bluuebunny/crossref_metadata_2025_split huggingface dataset:
Broad‐Temperature Optical Thermometry via Dual Sensitivity of Self‐Trapped Excitons Lifetime and Higher‐Order Phonon Anharmonicity in Lead‐Free Perovskites
Authors: Niu Guangming , Jiang Jutao , Zeng Xiangyu , Liu Xin , Wang Xiaowei , Zhang Yutong , Che Li , Sui Laizhi , Wu Guorong , Yuan Kaijun , Yang Xueming 
Published: January 2025

AbstractBroad‐temperature optical thermometry necessitates materials with exceptional sensitivity and stability across varied thermal conditions, presenting challenges for conventional systems. Here, we report a lead‐free, vacancy‐ordered perovskite Cs2TeCl6, that achieves precise temperature sensing through a novel combination of self‐trapped excitons (STEs) photoluminescence (PL) lifetime modulation and unprecedented fifth‐order phonon anharmonicity. The STEs PL lifetime demonstrates a highly temperature‐sensitive response from 200 to 300 K, ideal for low‐to‐intermediate thermal sensing. In contrast, the Eg phonon mode undergoes significant linewidth broadening due to five‐phonon scattering processes, with a distinct nonlinear temperature dependence up to 500 K. This fifth‐order anharmonic effect enhances Raman‐based temperature sensitivity, yielding a specific sensitivity (Sr) of 0.577 % K–1 at 330 K and remaining above 0.5 % K–1 at elevated temperatures. This study presents the first evidence of fifth‐order anharmonic effects enhancing Raman‐based temperature sensitivity, establishing Cs2TeCl6 as a versatile candidate for broad‐temperature optical thermometry and opening new avenues for precise non‐contact temperature sensing in advanced technological applications.
Crystalline, Porous Figure‐Eight‐Noded Covalent Organic Frameworks
Authors: Li Yaling , Tao Shanshan , Chen Yongzhi , Ye Xingyao , Shao Haipei , Lin Ming , Zhi Yongfeng , Jiang Donglin 
Published: January 2025

AbstractFigure‐eight macrocycles represent a fascinating class of π‐conjugated units characterized by unique aesthetics and non‐contact molecular crossing at the center. Despite progress in synthesis over the past century, research into inorganic, organic, and polymeric figure‐eight materials remains in its infancy. Here we report the first examples of figure‐eight covalent organic frameworks by condensing figure‐eight knots to create extended porous figure‐eight π architectures. A distinct feature is that polymerization interweaves figure‐eight knots into double‐decker layers, which upon supramolecular polymerization organize well‐defined layer frameworks. The figure‐eight frameworks exhibit a band gap of 2.3 eV and emit bright orange florescence with benchmark quantum yields. Remarkably, the donor‐acceptor figure‐eight skeletons convert the figure‐eight knots into reduction centers and the linkers into oxidation sites upon light irradiation, enable charge transport and accumulation through π columns, while the built‐in hydrophilic micropores allow rapid water and oxygen delivery via capillary effect. With these distinct features, the figure‐eight frameworks function as a photocatalyst to produce hydrogen peroxide at high rate and efficiency with water/saltwater, oxygen/air, and light as sole inputs. This work paves a way to a new class of molecular frameworks, underpinning the study of well‐defined figure‐eight materials to explore unprecedented structures and functions so far we untouched.
Dual‐Asymmetric Solid Additive Enables Eco‐friendly All‐Polymer Solar Cells with Over 19 % Efficiency and Excellent Stability
Authors: Liang Qiming , Li Henan , Xu Wan , Lu Junyi , Ma Ruijie , Bai Qingqing , Sun Xiaokang , Chen Mingqing , Zhu Liangxiang , Liu Qian , Guo Yuting , Zhang Guangye , Xue Qifan , Iwan Agnieszka , Cheng Pei , Hu Hanlin , Wang Hua , Chen Junwu , Niu Li , Sun Huiliang 
Published: January 2025

AbstractThe optimization of morphology in all‐polymer solar cells (all‐PSCs) often relies on the use of solvent additives. However, their tendency to remain trapped in the device due to high boiling points leads to performance degradation over time. In this study, we introduce a novel approach involving the design and synthesis of one dual‐asymmetric solid additive featuring mono‐brominated‐asymmetric dithienothiophene (SL‐1). Leveraging the synergistic effects of asymmetric substitution and core structures, fine‐tuning the molecule dipole moment enhancing solid additive interactions with host materials, thereby regulating polymer aggregation and influencing blend morphology during device fabrication. This results in highly ordered π–π stacking and a favorable phase‐separated morphology within all‐polymer active layer. Our work achieved a record efficiency of 19.19 % in eco‐friendly all‐PSCs, significantly outperforming SL‐0 (18.37 %) and SL‐2 (16.60 %), both featuring an asymmetric core. Furthermore, SL‐1‐treated all‐PSCs retain over 90 % of their initial efficiency after 2140 hours of operation, with an extrapolated T80 lifetime reaching 12400 hours. This represents a significant improvement in stability compared to devices treated with solvent additive (1‐CN), which typically exhibits a T90 lifetime of 700 hours. Our findings underscore the efficacy of utilizing dual‐asymmetric solid additives as a straightforward and viable strategy for optimizing all‐polymer morphology. SL‐1 represents a promising advancement towards eco‐friendly fabrication and application of high‐efficiency and stable all‐PSCs.
Applications of Verdazyl Radicals in Energy Storage, Molecular Electronics and Magnetism: Teaching Old Molecules New Tricks
Authors: Duggin Margot , Bissember Alex C. , Fuller Rebecca O. 
Published: January 2025

AbstractVerdazyls are a fundamental class of stable organic radicals that have been traditionally overshadowed by the more synthetically accessible stable nitroxide radicals. With the advent of enhanced synthetic routes to verdazyls, particularly in recent years, these systems are now poised to realise their potential in a range of applications across emerging technologies that will be important to addressing challenges faced by modern society. This review discusses the enabling properties of a selection of verdazyl‐based systems that feature promising applications in energy storage, molecular electronics and magnetic molecules. Emphasis is placed on progress in these areas over the past ~5 years.
Waves of Change: African American Leaders Transforming the Water Sector
Authors: Parks Carita 
Published: January 2025

Key TakeawaysAWWA members and water utility leaders are paving the way for expanded diversity—and a focus on welcoming and belonging—in the water industry as envisioned in AWWA's 2030 Strategic Plan and Water 2050 initiative.With a growing number of African American water professionals setting the tone for the utilities they lead, their communities benefit from a heightened level of understanding.Being an African American leader in the water industry has unique challenges, but setting an example for underrepresented professionals and future generations is an integral driver of their work.The seven people interviewed for this article stressed common leadership principles: building relationships, aligning with customers’ needs; advocating for diversity, equity, inclusion, and belonging; removing barriers to professional growth; and inspiring newcomers to the world of water.
Impact of Co‐doping Eu3+ and Gd3+ in HMO‐Based Glasses for Structural and Optical Properties and Radiation Shielding Enhancement
Authors: D'Souza Ashwitha Nancy , Madivala Sumanth G. , Saraswathi A. Vidya , Sayyed M. I. , Rashad M. , Kamath Sudha D. 
Published: January 2025

ABSTRACTEu‐Gd co‐doped glasses composed of 15B2O3–12SiO2–(40‐x)TeO2–3Eu2O3–xGd2O3–12Bi2O3–8BaO–10ZnO with x = 0–4 mol% (coded as EuGd‐x) were fabricated using melt quench approach to develop transparent radiation shielding system. Their structural, optical and mechanical properties were examined. 5.3663, 5.4264, 5.7405, 5.4683 and 5.6756 g/cm3 were the densities of EuGd‐0, EuGd‐1, EuGd‐2, EuGd‐3 and EuGd‐4, respectively. Gamma shielding ability of EuGd system was simulated using the Photon Shielding and Dosimetry software in energy spectrum 0.015–15 MeV. On co‐doping Gd3+ with Eu3+, clear advancement in gamma and neutron shielding ability was perceived; EuGd‐2 dominates because of the highest density. At 0.662 MeV, the uppermost and lowermost (0.501 and 0.468 cm−1) linear attenuation coefficients (LAC) were demonstrated by EuGd‐2 and EuGd‐0, respectively. EuGd‐2 distinguished itself with least half value layer (HVL) = 1.383 cm at 0.662 MeV, compared to EuGd‐0 (1.483 cm). Photon build‐up inside the glasses declined with Gd concentration at low gamma energies (< 2 MeV). EuGd‐2 also showcased maximum fast neutron removal (FNR) cross‐sectional value (0.10935 cm−1). Comparison between singly doped Eu2O3, Gd2O3 glasses and the current co‐doped glasses established that EuGd‐2 is the superior gamma shield in terms of LAC, HVL and effective atomic number.
A Comparison of the Optical Properties of Fibre‐Based Luminescent Solar Concentrators and Transparent Wood Towards Sustainable Waveguides
Authors: Mohan Brindha V. G. , Shobhana V. G. , Boopathi N. Manikanda 
Published: January 2025

ABSTRACTAiming at net‐zero emissions, most international and national policies focus on sustainable development goals. Hence, there is an immediate need for replacing carbon‐intensive materials with biomaterials. In this respect, this article presents a road‐map for moving from polymeric to sustainable waveguides in optical devices. Previous reports indicate that luminescent fibres exhibit better photon concentrations of nearly 30%–33% higher than flat‐plate polymeric waveguides. It is also verified that the photon in‐out ratio increases by 3.44 times when the waveguide geometry is changed from planar to an equivalent area of fibre bundle with the same luminophore. Meanwhile, transparent wood (Twood) is gaining attention as a green alternative to acrylic sheets. The structure and function of transparent wood conforms well with the fibre‐based waveguides of luminescent solar concentrators (LSCs). Therefore, it is intriguing to compare Twood with intrinsic micro fibrillary interior with fibre‐based LSC as a natural alternative. This review provides an in‐depth analysis, emphasizing the benefits and associated challenges in using cylindrical concentrators over planar LSCs. The paper collects and compares the phenomenon of light guiding of cylindrical and fibre‐based LSCs with that of Twood. It is important to consider the key points discussed here while making a transition towards sustainable waveguides.
Fluorometric Turn Off Detection of Cu2+ and Pd2+ Ions Using 1‐(Imidazo[5,1‐a]isoquinolin‐3‐yl)naphthalen‐2‐ol
Authors: Kumar Sandeep , Phogat Hitesh , Manivannan Vadivelu 
Published: January 2025

ABSTRACTThe fused heterocycle 1‐(imidazo[5,1‐a]isoquinolin‐3‐yl)naphthalen‐2‐ol (LH) has been synthesized and characterized by spectroscopic methods. Probe LH upon irradiation with λex = 336 nm exhibited strong fluorescence with λem = 437 nm in MeOH/HEPES buffer (5 mM, pH = 7.4, 2:8, v/v). Upon adding several metal ions, the fluorescence intensity was quenched only by Cu2+ and Pd2+ ions. This fluorescence turn‐off response by Cu2+ and Pd2+ ions was observed even in the coexistence of other metal ions and anions. From the Job's plot and mass spectra analysis, a 2:1 ratio of LH:M2+ was obtained, and the composition [Cu(L)2H2O] and [Pd(L)2] has been assigned. The detection limit for Cu2+ and Pd2+ ions was determined to be 0.24 and 0.35 μM, respectively, and workable pH window to be 4–10. The binding of LH to Cu2+ and Pd2+ resulted in red‐shift in the UV–visible spectrum, which was supported by DFT/TDDFT calculations.
Characterization of large transgene integrations in Chinese hamster ovary cells using a bioengineered mammalian transposase
Authors: Marx Nicolas , Otte Anna‐Maria , Leitner Klaus , Sitepu Rehmadanta , Berger Thomas , Schäpertöns Veronika , Huber Christian G. , Zhu Quan , Nema Sandeep , Higgins Joseph J. , Borth Nicole 
Published: January 2025

AbstractWe present the first use of a bioengineered mammalian transposase system derived from Myotis lucifugus (bMLT) for integration of expression vectors into the CHO genome, focusing on GFP and trastuzumab production. Initially, CHO‐K1 cells are transfected with a GFP reporter and varying amounts of bMLT DNA or mRNA. GFP expression is monitored over 17 weeks without selective pressure. Transfection efficiency shows around 90% GFP‐positive cells, but in control cultures GFP expression disappears after 10 days. In contrast, bMLT‐treated cultures maintain stable GFP expression, with a dose‐dependent integration efficiency of up to 60%. The highest GFP expression per cell is observed with lower bMLT amounts. Next‐generation sequencing analysis reveals multiple integration sites, with 85% correctly integrated sequences. Next, CHO‐GS−/− cells are transfected with trastuzumab and bMLT DNA or mRNA. Cells are selected in glutamine‐free medium with varying methionine sulfoximine (MSX) concentrations. Recovery is faster without MSX, and no difference is observed between bMLT DNA and mRNA transfections. bMLT‐treated cultures show a higher percentage of trastuzumab‐secreting cells (40%–55%) compared with random integration (0.3%–0.5%). The absence of insulators in the trastuzumab plasmid likely affects selection behavior, as integration in heterochromatic regions results in gene repression. Overall, bMLT‐mediated integration proves efficient, generating stable cell pools with high expression profiles without selective pressure. The integration sites' genomic location significantly impacts productivity, with favorable regions supporting higher expression. This method shows promise for the rapid and efficient generation of high‐producing cell lines and for rapid evaluation of long‐term effects of different cell engineering approaches.
Deciphering the Differences Between Epstein–Barr Virus‐Associated and Negative Gastric Cancer in the Prospect of CDKN2A Genomic Alterations and Lymphoid Infiltration
Authors: Xie Fuda , Chen Bonan , Lyu Yang , Yu Peiyao , Fang Canbin , Leung Kam Tong , Wang Shouyu , Xu Dazhi , Yu Jun , Lo Kwok Wai , To Ka Fai , Kang Wei 
Published: January 2025

ABSTRACTBackgroundGastric cancer (GC) is a major health concern worldwide. One important contributing factor is the presence of the Epstein‐Barr virus (EBV). However, the molecular pattern of how EBV participates in the malignant transition process remains unclear.MethodsGC samples were stained by immunohistochemistry, fluorescent and EBV‐encoded small RNA in situ hybridization to identify CD8 expression, CDKN2A genomic alteration, and EBV existence. Functional potentials of EBV infection were predicted by bioinformatic enrichment analysis.ResultsCDKN2A genestayed intact in all EBV‐associated GC cases. Meanwhile, CDKN2A deletion (8.43% cases) was exclusive to EBV‐negative GC cases. Furthermore, EBV infection was positively correlated with CD8+T cell infiltration, and both of them predicted better prognosis.ConclusionThis study highlighted the comprehensive impact of EBV infection in GC formation and proposed a thought‐provoking observation for further investigation into the roles of CDKN2A and EBV infection in gastric tumorigenesis.
Characterization and Detection Strategy Exploration in Cryptogenic Hepatocellular Carcinoma: Insights From a Super‐Aged Region in Japan
Authors: Sugihara Takaaki , Nagahara Takakazu , Kihara Takuya , Ikeda Suguru , Hoshino Yoshiki , Matsuki Yukako , Sakaguchi Takuki , Kurumi Hiroki , Onoyama Takumi , Takata Tomoaki , Matono Tomomitsu , Isomoto Hajime 
Published: January 2025

ABSTRACTBackground and AimIn recent years, there has been a rise in cryptogenic hepatocellular carcinoma (c‐HCC) cases in Japan, posing a detection challenge due to an unknown etiology. This study aims to enhance diagnostic strategies for c‐HCC by analyzing its characteristics and exploring current opportunities for detection.MethodsA retrospective study was conducted from April 2012 to March 2022, enrolling 372 newly diagnosed hepatocellular carcinoma (HCC) patients. Excluding cases associated with hepatitis viral infection, alcoholic liver disease, non‐alcoholic fatty liver disease/steatohepatitis, autoimmune hepatitis, primary biliary cholangitis, and congestive hepatopathy, the study specifically focused on genuine c‐HCC. The analysis delved into the characteristics, detection opportunities, and survival outcomes associated with c‐HCC.ResultsAmong the non‐viral HCC cases, 55 patients (29.3%) (34 men and 21 women) were diagnosed with c‐HCC, making it the second‐highest etiology. Notably, individuals with c‐HCC, typically aged 60 and above (median age 76.0), exhibited a women predominance and presented with larger tumors (4.5 cm vs. 2.5 cm), correlating with a poorer prognosis. Cirrhosis was notably absent in most c‐HCC cases (72.7%), and more than half (56.4%) did not have diabetes mellitus (DM). Diagnostic pathways for c‐HCC primarily involved incidental imaging (47%) and symptoms (24%). Within the cohort of c‐HCC, the prognosis for symptomatic cases is notably unfavorable compared to other cases [median survival time 19.0 (7.0–45.0) months vs. 47.0 (29.0–76.0) months, p = 0.029]. In the multivariate regression analysis, age and women emerged as independent factors associated with c‐HCC. Rather than a significant increase in women, there is a narrowing gender gap.ConclusionPatients with c‐HCC were predominantly elderly, without cirrhosis or diabetes, and exhibited minimal gender differences. Detection often occurred incidentally through abdominal imaging. Considering the limitations of conventional surveillance, it seems reasonable to propose that abdominal imaging be included in cancer screening, particularly for individuals aged 60 and older.Trial Registration1610A127
Unveiling Cannabinoids and Terpenes Diversity in Cannabis sativa L. From Northern India for Future Breeding Strategies
Authors: Ghosh Dipayan , Kundu Anitika , Chaudhary Neha , Gupta Darshan , Dwivedi Mridula , Verma Ram Swaroop , Shanker Karuna , Kumar Birendra , Kumar Narendra 
Published: January 2025

ABSTRACTCannabis sativa L. is an important medicinal plant with high commercial value. In recent years, the research interest in cannabidiol (CBD) and terpene‐rich cannabis has been rapidly expanding due to their high therapeutic potential. The present study aims to explore the phytocannabinoids and terpenes diversity in C. sativa collected from different parts of northern India. Our findings revealed that the cannabinoids and terpenes synthesize together in capitate stalked and capitate sessile glandular trichomes, whereas bulbous glands synthesize only terpenes. The North Indian C. sativa is mainly dominated by tetrahydrocannabinol. The CBD‐rich plant diversity is nominal (1.11%) in studied north Indian C. sativa. The essential oil profiling reveals (E)‐caryophyllene (10.30%–36.80%) as the major constituent, followed by α‐humulene (0.50%–15.29%) and α‐bisabolol (0.00%–16.40%) in the North Indian population. The cannabinoids and terpenes content showed significant diversity among and within the five studied populations. The correlation analysis between cannabinoids and terpenes indicates that α‐pinene, β‐pinene and limonene positively correlated with CBD content. Similarly, α‐ and β‐selinene correlate positively with tetrahydrocannabinolic acid content. This study could help to identify the key cultivars from India and establish a consistent chemotype for future breeding programs.
Synthesis, Characterization, Anti‐Nematicidal, and Computational Study of Copper(II) Complex Derived From Fluoro‐substituted Schiff Base Ligand
Authors: Lawan Salisu Y. , Ndahi Naomi P. , Galadima Ibrahim B. , Wahab Olaide O. , Yusuf Tunde L. , Coetzee Louis‐Charl C. , El‐Maksoud Mostafa S. Abd , Waziri Ibrahim 
Published: January 2025

ABSTRACTIn this study, a novel fluoro‐substituted Schiff base ligand (HL) was synthesized through a condensation reaction between 2‐bromo‐4‐(trifluoromethoxy)aniline and 2‐hydroxybenzaldehyde in methanol solvent at room temperature. The ligand was subsequently reacted with copper(II) acetate to produce the corresponding Cu(II) complex (CuL2). Both the ligand and its complex underwent characterization using various techniques including nuclear magnetic resonance, ultraviolet‐visible, Fourier‐transform infrared, thermogravimetric analysis, elemental analysis, and mass spectroscopy. In addition, the solid‐state structure of the complex was determined through single crystal X‐ray diffraction analysis, confirming the successful isolation of the compounds. Subsequently, the nematicidal activities of the ligand and its complex were assessed through in vitro egg hatching inhibition and mortality rate assays, in comparison to the control, carbofuran (Crf), at concentrations of 50 and 100 µM over a 24–72‐h period. The results indicated the ligand's superiority over the complex in both assays at lower concentrations. At a concentration of 50 µM, the ligand HL demonstrated 100% egg‐hatching inhibition at 24, 48, and 72 h, whereas the complex CuL2 showed egg‐hatching inhibition rates of 93.86 ± 0.22%, 98.76 ± 0.14%, and 99.33 ± 0.52% at the same time intervals. The control, Crf, exhibited inhibition rates of 56.33 ± 0.33%, 69.94 ± 0.6%, and 67.00 ± 0.34% over the same time period. Similarly, at a concentration of 100 µM, both the ligand and complex demonstrated 100% egg‐hatching inhibition at 24, 48, and 72 h, while the control showed egg‐hatching rates of 88.16 ± 0.84%, 89.9 ± 0.55%, and 90.8 ± 0.50%. Regarding the mortality rate, at 50 and 100 µM, the ligand HL exhibited a 100% mortality rate within 24 to 72 h, whereas the complex CuL2 displayed mortality rates of 56.66 ± 0.33%, 63.3 ± 0.23%, and 86.66 ± 0.13% at 24, 48, and 72 h, respectively, with a mortality rate of 100% at 100 µM within the same time intervals. The control, Crf, demonstrated mortality rates of 54%–67% at 50 µM and 62%–78% at 100 µM within 24–72 h. Additionally, the density‐functional theory study revealed the electronic properties of the compounds, reinforcing the experimental findings.
Enhanced Carbon Dioxide Capture: Adsorption and Physicochemical Properties of SBA‐15 Mesoporous Silica
Authors: Mahendran Shalini , Yahaya Noorfatimah , Hameed Bassim H. , Vo Dai Viet N. , Ouakouak Abdelkader , Nishiyama Norikazu , Mohd Din Azam Taufik 
Published: January 2025

AbstractGlobal warming is widely recognized as one of humanity's most urgent challenges, making CO2 capture from the environment crucial to mitigating problems associated with climate change. In this study, ordered mesoporous silica SBA‐15 was synthesized using the sol–gel process with Pluronic P123, a nonionic surfactant, and tetraethyl orthosilicate as the silica source, with hydrochloric acid serving as the catalyst. The results indicated that the CO2 adsorption capacity of SBA‐15 was improved with higher CO2 feed concentration but decreased with increasing flowrate, temperature, and adsorbent loading. The Avrami model provided the best fit for the experimental kinetic data. The Thomas and Yoon–Nelson models were successful in predicting the CO2 adsorption performance of SBA‐15 in the fixed‐bed column system. The synthesized SBA‐15 demonstrated its significant potential as a cost‐effective CO2 adsorbent by maintaining a high adsorption capacity, even after multiple regeneration cycles.