bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oligoarthrite hémophilique acquise chez un adolescent togolais au CHU Kara
Authors: Diallo Mamadou Lamine , Oniankitan Sadat , Kamissoko Aly Badra , N’timon Bidamin , Lokou Poyodé , Ataké Awaki Esso , Baldé Mamadou Dian , Houzou Prénam , Oniankitan Owonayo 
Published: October 2023

Haemophilia is a congenital X-linked haemostasis disorder, the severity of the haemorrhagic manifestations of which is correlated with that of the coagulation factor deficiency (F VIII or F IX). Hemophilic arthropathy is the leading cause of morbidity in severe hemophilia patients. Hemophylic arthritis results from the repetition of a certain number of hemarthroses affecting a so called “target” joint, characterized by synovial hypertrophy, synovial deposits of hemosiderin, cartilage destruction and modification of the adjacent bone. We report a case of hemophilic arthritis in a 17-year-old Togolese patient.
L’hémophilie est une affection congénitale de l’hémostase liée au chromosome X, dont la sévérité des manifestations hémorragiques est corrélée à celle du déficit en facteur de coagulation (F VIII ou F IX). L’arthropathie hémophilique constitue la première cause de morbidité chez les patients hémophiles sévères. L’arthrite hémophilique résulte de la répétition d’un certain nombre d’hémarthroses touchant une articulation dite « cible », caractérisée par une hypertrophie synoviale, des dépôts synoviaux d’hémosidérine, une destruction cartilagineuse et une modification de l’os adjacent. Nous rapportons un cas d’arthrite hémophilique chez un patient togolais de 17 ans.
Mort in utero tardive : fréquence, facteurs associés et méthodes de déclenchement du travail à Kisangani, République Démocratique du Congo
Authors: Matega Teddy Habiragi , Labama Noel Otuli , Kanilame Frederic Yabila , Maindo Mike- Antoine Alongo , Juakali Jean-Jeannot Syhalikyolo , Katenga Gédéon Bosunga 
Published: October 2023

Context and objective. Late fetal death (LFD) refers to spontaneous in utero death (IUD) at 28 weeks of age or more, but before the onset of labor, which is a tragedy for the mother, her family members and caring staff. This study seeks to determine its frequency, associated factors, and methods of labor induction in Kisangani.
Methods. This was a cross-sectional, multicentric descriptive study conducted in 3 hospitals in Kisangani covering a 3-year period. Data collection of LFD cases from 28 weeks was retrospective. The collected data were encoded on an Excel 2013 sheet and analyzed using EPI-INFO 7.2.2.6 Software.
Results. The frequency of LFD was 6.48%. The main associated factors were upper urinary tract infection (35.4%), malaria (27.5%) and hypertension (27.5%). The rate of participation in prenatal consultations was only 63.5%. The methods of labor induction used were misoprostol (42.7 %), oxytocin solution (17.7 %) or both combined (25 %). Cesarean section was indicated at a rate of 26,4%.
Conclusion. The frequency of LFD in Kisangani is high. Pyelonephritis, malaria and hypertension are the main associated factors. Misoprostol and oxytocin are the most commonly used methods of labor induction. Regular follow-up of prenatal consultations would reduce the rate of LFD.
Contexte et objectif. La mort fœtale tardive fait référence à la mort in utéro (MIU) de survenue spontanée à partir de 22 semaines d’aménorrhée (SA), mais avant tout début du travail d’accouchement, ce qui constitue une tragédie pour la mère, les membres de la famille et du personnel soignant. La présente étude a déterminé l’ampleur, les facteurs associés et les méthodes de déclenchement artificiel du travail d’accouchement sur MIU.
Méthodes : Il s’est agi d’une étude transversale descriptive, multicentrique menée dans 3 hôpitaux de Kisangani, pendant une période de 3 ans. La collecte des données était rétrospective, des cas de MIU à partir de 28 SA.
Résultats : La fréquence de MIU tardive était de 6,48%. Les principaux facteurs associés étaient l’infection urinaire (35,4%), le paludisme sur grossesse (27,5%) et l’hypertension artérielle gravidique (27,5%). Le taux de participation aux consultations prénatales (CPN) n’était que de 63,5 %. Les méthodes de déclenchement artificiel du travail d’accouchement utilisées étaient le Misoprostol (42,7%), l’ocytocine (17,7%) soit les deux combinées (25%). La césarienne était indiquée à un taux de 26,4%.
Conclusion : la fréquence de MIU tardive est élevée à Kisangani. L’infection urinaire, le paludisme et l’hypertension artérielle en constituaient les principaux facteurs associés. Le Misoprostol était la méthode de déclenchement du travail les plus utilisées. Un suivi régulier des CPN pourrait réduire le taux de MIU.
Effect of SMEs (Cotton Ginnery Industry) on Social Living in Zamfara State, Nigeria
Authors: Abdullahi Mansur , Haruna Abdullahi Ibrahim 
Published: October 2023

This study examined the effect of one of the SMEs; cotton ginnery industry on social living in Zamfara State. The study used primary data, obtained from 272 respondents, who were randomly selected. Consequently, descriptive statistics and multiple regressions were employed. The results revealed that, cotton ginnery industry has positive effect on social living. Finally, the study recommended among others that, government should improve its financial and policy support to ginnery industry, so that they could create more income and employment opportunities both directly and indirectly to the citizenry in the state, hence enhance social living of millions of people in Zamfara State in particular, and Nigeria in general.
Foreign Debt, Institutional Quality and Economic Performance in Nigeria: An Experimental Evaluation
Authors: Ekpe John Polycarp , Ogbuabor Jonathan E. 
Published: October 2023

Nigeria is the largest economy in Africa and the largest exporter of crude oil in Africa, yet Nigeria has a huge foreign debt portfolio and weak institutions. It is against this backdrop that this study examines the impact of foreign debt and institutional quality on economic performance in Nigeria. Data used for the analysis were quarterly data that ranges from 1996Q1 to 2019Q1. Foreign debt service was used as a measure of foreign debt while corruption control and government effectiveness were used as measures of institutional quality. Economic performance which is the dependent variable was measured using Gross Domestic Product. The study also examines how institutional quality influences the relationship between foreign debt and economic performance in Nigeria. Autoregressive Distributed Lag Model was used to specify and estimate the relationship between the variables. The result of the analysis indicates that foreign debt has an insignificant negative effect on economic performance in the short run and also negative insignificant effect in the long run too, corruption control has a significant positive effect on economic performance only in the short run, Government effectiveness does not have a significant effect in the economy, being the two; the short run and the long run, on that account corruption control influences the relationship between foreign debt and economic performance significantly and negatively only in the short run but also positively and insignificantly in long run. Mechanism should be put in place to ensure that foreign debts are properly utilized on the projects they were meant for.
Work Engagement as the Mediator of the Relationship between Workplace Civility and Workplace Deviant Behaviour among Employees of Tertiary Institutions in Zamfara State
Authors: Kareem Rafiu Falola , Ojeleye Chioma Ifeoma , Sodamade Issa Olaniyi 
Published: October 2023

This study explores the relationship between workplace civility, work engagement and workplace deviant behaviour, as well as the mediating role of work engagement in the relationship between workplace civility and workplace deviant behaviour. To this end, a survey was developed and administered to 424 employees across the selected tertiary institutions in Zamfara State, Nigeria. Structural equation modeling (SEM) was used to analyse the data collected. Results show that workplace civility has negative and significant effect on workplace deviant behaviour. Additionally, work engagement is also found to significantly mediate the relationship between workplace civility and workplace deviant behaviour. The study concluded that employers should promote a culture of workplace civility in order to maintain employee engagement and reduce workplace deviance. Furthermore, employers should also strive to foster an atmosphere of respect and appreciation among employees. The implications for further research on the topic are discussed.
An Evaluation of Happiness Status of Academic personnel in Nigerian University Community: Work Environ Perspective
Authors: Agboluaje Ayodele Abraham , Ewugi Musa Salihu , Mohammed Aliyu Bello 
Published: October 2023

Educationists, in recent times have accepted the importance of happiness in human life. They have acknowledged that teaching and learning goals and objectives are consistent with happiness. Quality and equity education lead to the enhancement of capabilities and functioning, which facilitates positive life that brings about happiness and development. The ideal university system generally enhances happiness of the university community which overflows in the society. It is in line with these assertions that this work aimed to ascertain the happiness status of academic personnel in Nigerian University community with emphasis on their working environment. Linear Regression Model method was employed and the work discovered that the academic personals of the Nigerian university community are not happy. The work therefore, concludes that university teachers/lecturers are key when it comes to building society’s happiness and recommends that university academic community be taken more seriously in terms of provisions that will enhance their happiness.
Development of a Mobile-Based Convolution Neural Network Framework for Rapid Malaria Detection from Blood Smears
Authors: Oladele Matthias O. , Adepoju Temilola M. , Badrudeen Abdulahi A. 
Published: October 2023

Malaria, a vector-borne parasitic disease caused by Plasmodium parasites, continues to pose a substantial threat to global public health. Despite considerable progress in its control and treatment, malaria remains a significant cause of morbidity and mortality, particularly in resource-limited regions. The ability to diagnose malaria infections accurately and swiftly is paramount for effective disease management. Traditional methods of malaria diagnosis, relying on microscopic examination of blood smears, have proven to be accurate but are often hindered by limitations in infrastructure and expertise, particularly in remote and underserved areas. This research focuses on the development of a mobile-based Convolution Neural Network (CNN) framework for rapid malaria parasite detection from blood smear images using Android mobile phones. Blood smear images provide a reasonable and clinically relevant representation of malaria disease which makes it a preferred choice for malaria detection from mobile phones. By leveraging smartphone technology and state-of-the-art deep learning algorithms, this pioneering endeavour aims to normalize malaria diagnostics, providing healthcare workers with a powerful tool for early detection and treatment, irrespective of their location or access to advanced laboratory facilities. The dataset for infected and non-infected parasites was acquired online from Kaggle. The dataset was preprocessed and partitioned into training, testing, and validation sets. The developed model was converted to tflite and was used for the mobile application. A validation accuracy of 94.88% was obtained from the validation set while an accuracy of 95.81% was obtained from the testing set.
Beauty Body (Body Composition) among Fat Loss Program Participants A Case Study Longitudinal Primary Study
Authors: Putri Dewi Atika , Handayani Dwi Ratna Sari , Rosyita Hafna , Waluyo Imam , Subu Muhamad Arsyad , Koniasari Koniasari 
Published: October 2023

Overweight and obesity can be risk factors for various diseases. The increasing prevalence of overweight and obesity is a public health problem and a challenge that needs to be addressed urgently. The purpose of this study is to periodically monitor body beauty (body composition) in clients running a fat loss program package. This type of research is a case study with a longitudinal design. The subjects in this study were clients who followed the fat loss program of 4 people who followed the program in June 2023 as determined by all subjects who followed the program in June 2023. Test instruments using meters and a Bioelectrical Impedance Analyzer (BIA-Omron) Data analysis using descriptive analysis of changes in body beauty indicators ( body composition ) The results show that: the fat loss program gives a decreased change in fat percentage before and after the program also reduces weight as well as increases muscle percentage thus giving a more proportional beautiful body appearance Based on the results, it can be concluded that the fat loss program descriptively gives good results for the improvement of body composition and fat percentage and weight loss.
Evaluation of Aflatoxin Contamination in Zea mays (Maize) Sold in Katsina Central Market, Nigeria
Authors: Shamsuddeen, U.  , Ahmad, M. A.  , Abdulkadir, R. S.  
Published: October 2023

This study was carried out to isolate moulds and detect Aflatoxin in maize sold in Katsina Central Market. A total of ten (10) samples of maize were collected from five different vendors in the market and subjected to mould isolation, Aflatoxin extraction and characterization of the toxin type using Thin Layer Chromatography (TLC). Four fungal genera namely Aspergillus, Penicillium, Fusarium and Rhizopus species were isolated from 7(70%), 1(10%), 3(30%) and 7(70%) of the samples respectively. Aspergillus species were the predominant species isolated with Aspergillus flavus occurring in 7(70) and Aspergillus niger 6(60) of the total samples. Extraction of the toxin was carried out using methanol and water while type of the toxin was determined using thin layer chromatography (TLC), in which blue fluorescence on the TLC plates in 7(70%) indicated the presence of aflatoxin B in the samples. Retention factor (RF) value with a range of 0.40-0.60 was calculated using the standard formulae. The research suggest proper harvesting, drying, storage and public enlightenment to avoid contamination and consumption of maize grains infested by the number one carcinogenic toxin.
Molecular Diagnostic Techniques for Malaria Infection - A Review
Authors: Yangora, Y.M.  , Usman, A.D.  
Published: October 2023

Malaria is the most threatening disease protozoal and a major health problem worldwide especially in developing countries. WHO recommended that for every case of suspected malaria, diagnostic test must be done to confirm the disease. A more advanced Diagnostic Techniques were developed to overcome the problem of conventional microscopy. These techniques are known as Molecular diagnostic techniques, and they detect specific sequence in DNA, RNA and proteins to provide clinical information for human pathogens including malaria parasites. There are several techniques involve in molecular diagnostics, some are however discussed in this review. They include Polymerase Chain Reaction (PCR), Loop-mediated isothermal amplification (LAMP), Flow Cytometric technique (FCM), Nucleic acid based sequence amplification (NASBA), and Luminex xMax technology. Among these techniques; LAMP technique is the best techniques that can be deployed in the field settings (clinical and rural settings) because of its simplicity, reliability, stability, detection method as well as point-of- care and confirmatory ability. On the other hand, PCR-based technique is more suitable for research purposes because it can be used to identify drug resistance, follow-up therapeutic response, and detect asymptomatic malaria carriers who may be targeted for treatment. Hence, molecular diagnostic techniques are most innovative science and technical implementations that can be used to diagnose malaria infection and to overcome the limitations.
Disparity of Biofilm Formation in Salmonella typhimurium on Glass and Wood Surfaces at Diverse Incubation Temperatures
Authors: Sani Aliyu  , Bello Usman  
Published: October 2023

Salmonella Typhimurium is a pathogenic gram-negative bacterium that commonly causes food- borne diseases known as gastroenteritis. Biofilm can exist on many surfaces in food preparation
e.g glass, wood, plastic, metal and other food items. The aim of this study was to evaluate and quantify the biofilm formation of S. typhimurium on food contact surfaces (glass and wood) at different intervals (24, 48 and 72 hours) and different incubation temperatures (10, 28 and 37 oC). The inoculum used was 108 CFU ml-1 of S. typhimurium. Formation of biofilm was quantified using beads vortex and agar plate count method. Biofilm of S. typhimurium was formed on both surfaces with preference more to glass surfaces, but all the densities of biofilm formed can cause infections. On Glass surfaces a total of 1.62x109 CFU ml-1 S. typhimurium was achieved as the highest biofilm density. Thirty seven degree was the most preferred incubation temperature of S. typhimurium cells, through which the highest biofilm cells were formed and 10oC incubation temperature supported the least biofilm densities. The result showed that, the biofilm formation of S. typhimurium was influenced by incubation temperatures and increases with time.
Crispr Cas System in Plant Genome Editing a New Opportunity in Agriculture to Boost Crop Yield
Authors: Sunusi, M.  , Lurwanu, Y.  , Halidu, J.  , Musa, H.  
Published: October 2023

Clustered regularly interspaced short palindromic repeats CRISPR/Cas9 technology evolved from a type II bacterial immune system develop in 2013 This system employs RNA-guided nuclease, CRISPR associated (Cas9) to induce double-strand breaks. The Cas9-mediated breaks are repaired by cellular DNA repair mechanisms and mediate gene/genome modifications. The system has the ability to detect specific sequences of letters within the genetic code and to cut DNA at a specific point. Simultaneously with other sequence-specific nucleases, CRISPR/ Cas9 have already breach the boundaries and made genetic engineering much more versatile, efficient and easy also it has been reported to have increased rice grain yield up to 25-30 %, and increased tomato fruits size, branching architecture, and overall plant shape. CRISPR/ Cas also mediated virus resistance in many agricultural crops. In this article, we reviewed the history of the CRISPR/Cas9 system invention and its genome-editing mechanism. We also described the most recent innovation of the CRISPR/Cas9 technology, particularly the broad applications of modified Cas9 variants, and discuss the potential of this system for targeted genome editing and modification for crop improvement.
Abbreviations: CRISPR, clustered regularly interspaced short palindromic repeats; Cas, CRISPR associated; crRNA, CRISPR RNA; tracrRNA, trans-activating crRNA; PAM, protospacer adjacent motif; sgRNA, single guide RNA; gRNA, guide RNA; ssODN, single-stranded DNA oligonucleotide; DSB, double-strand break; NHEJ, non-homologous end joining; HDR, homology directed repair, CRISPRi ,CRISPR interference
Effects of Malaria Infection on Haematological Parameters among Patients in Kano State, Nigeria
Authors: Adamu, A. Y.  , Olonitola, O. S.  , Inabo, H. I.  , Suleiman, A. B.  
Published: October 2023

Destruction and alteration of blood cells especially erythrocytes are the common devastating effects of malaria infection. This leads to haematological changes often characterised by anaemia, thrombocytopaenia and leucocytosis or leucopaenia. The aim of this study is to assess the effects of malaria infection on erythrocytes and leucocytes with associated risk factors.
200 malaria positive patients were enrolled in this study. The patients’ haematological parameters and parasitemia level were assessed. Plasmodium falciparum was detected in 197 (98.5%) patients as the most predominant specie while 3 patients had mixed infection. A mean parasite density of 11,496 parasites/µL was observed with majority of the patients showing parasitaemia of <10,000 parasites/µL. Age groups 1-5yrs, 6-15yrs and 26-35yrs had patients that recorded parasitaemia of >50,000 parasites/µL. The mean white blood cells count, neutrophils and eosinophils count in malaria infected patients were seen to be increased compared to the malaria negative control group. Haemoglobin concentration, haematocrit level and mean cell haemoglobin were however seen to be lower in the malaria positive patients than the control group. Majority of the patients had hypochromia indicated by lower mean cell haemoglobin which increases with severity of malaria infection. Haematological changes can be used to depict severity of malaria infection among all age groups.
Seroprevalence of Anti HSV-2 IgG among Women of Reproductive Age attending General Hospital Dutse
Authors: Sani, N. M.,  , Rukayya, H.M.,  , Ubandoma, M.S.,  , Mujahid, N.S.  , Oni, M.A.  , Isaka, I.  
Published: October 2023

Herpes simplex virus type 2 (HSV-2) remains one of the widespread and chronic sexually transmitted infections (STI) globally with highest disease burden in African females. A study to determine the humoral immune response to HSV-2 was carried out with a view to “x- raying” the magnitude of the infection among females of reproductive age in Dutse. A total of 94 clients were recruited for the study and Samples were randomly collected after obtaining their consent. A structured questionnaire was administered to capture demographic information in addition to knowledge, attitude and practices of each respondent. Samples were tested for the presence of IgG antibodies against HSV-2 using enzyme linked immunosorbent assay (ELISA). Results were further subjected to Chi-square test using SPSS version 22.0 where p-values of ≤ 0.05 were considered statistically significant. Out of the 94 samples tested, 29 (30.9%) were positive for anti HSV-2 IgG with high Seroprevalence rates among all age groups. However, age group 15-19 recorded the highest Seroprevalence of 46.2%. Similarly, age groups 20-29, 30-39 and ≥ 40 recorded 28.8%, 26.3% and 33.3% respectively. Chi- square test showed that Seroprevalence of HSV-2 was not significantly associated with age, marital status or level of education. However, it was strongly associated with number of sexual partners (p= 0.048). Higher Seroprevalence was also recorded among women with no educational exposure than those with at least primary or higher level of education. However, Seroprevalence of infection was not statistically associated with level of education p= (0.059). Married women recorded a higher Seroprevalence than the singles. The findings of this research indicates a high Seroprevalence of Herpes Simplex - 2 Virus among women of reproductive age which implies a public health problem to the populace of Dutse and Jigawa state at large making it necessary for the government and other stakeholders to properly curtail the situation through public enlightenment, and implementation of other health policies.