bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tidal Dissipation in Stably Stratified and Semiconvective Regions of Rotating Giant Planets: Incorporating Coriolis Forces
Authors: Pontin Christina M. , Barker Adrian J. , Hollerbach Rainer 
Published: December 2023

Abstract
We study how stably stratified or semiconvective layers alter tidal dissipation rates associated with the generation of inertial, gravito-inertial, interfacial, and surface gravity waves in rotating giant planets. We explore scenarios in which stable (nonconvective) layers contribute to the high rates of tidal dissipation observed for Jupiter and Saturn in our solar system. Our model is an idealized spherical Boussinesq system incorporating Coriolis forces to study effects of stable stratification and semiconvective layers on tidal dissipation. Our detailed numerical calculations consider realistic tidal forcing and compute the resulting viscous and thermal dissipation rates. The presence of an extended stably stratified fluid core significantly enhances tidal wave excitation of both inertial waves (due to rotation) in the convective envelope and gravito-inertial waves in the dilute core. We show that a sufficiently strongly stratified fluid core enhances inertial wave dissipation in a convective envelope much like a solid core does. We demonstrate that efficient tidal dissipation rates (and associated tidal quality factors

Q
′

)—sufficient to explain the observed migration rates of Saturn's moons—are predicted at the frequencies of the orbiting moons due to the excitation of inertial or gravito-inertial waves in our models with stable layers (without requiring resonance locking). Stable layers could also be important for tidal evolution of hot and warm Jupiters and hot Neptunes, providing efficient tidal circularization rates. Future work should study more sophisticated planetary models that also account for magnetism and differential rotation, as well as the interaction of inertial waves with turbulent convection.
Speckle Tracking Analysis of Mitral Annular Calcification and Left Ventricular Mechanics
Authors: Allam Ahmed Mohammed Abd El Rahman , Mansy Ahmed Mahmoud Hasan , Fathy Asmaa Mohamed 
Published: December 2023

BACKGROUND: Clinical echocardiography often reveals mitral annular calcification (MAC), and this condition has been connected to atherosclerosis and cardiovascular risk factors. To this day, our knowledge of the left ventricle’s (LV) physiology is still somewhat restricted. Using 2D speckle tracking echocardiography, we analyzed the connection between MAC and LV mechanical functions (2DSTE).
AIM: The purpose of the current investigation is to assess how left ventricular mechanics are impacted by MAC.
MATERIALS AND METHODS: Between April 2020 and October 2021, this prospective and cross-sectional study was carried out in Islamic Center of Cardiology Al Azhar University and Cardiology Department of Al Hussien University Hospital. Eighty participants were utilized in the study. When necessary, patients were referred to the Cardiology Clinics at the Medical Schools of Al Azhar University for follow-up care. Sixty MAC patients were studied with 20 healthy controls of similar age and gender. All patients had a 2D echocardiogram. Sixty consecutive patients with a MAC diagnosis and 20 age- and sex-matched controls with normal cardiac evaluations made up the study population. The patients were all given a 2D echocardiogram.
RESULTS: The longitudinal strain significantly decreased as the MAC severity rose. The LV’s rotating mechanics varied greatly among MAC organizations. The E/A ratio, the global longitudinal speed (GLS), and the systolic tissue velocity were all shown to have a negative correlation with MAC thickness. Additional variables were found to have statistically significant connections. There were significant correlations between MAC severity and age, LV mass index, and t-LV UR. Age, LV mass index, and linear speed were significantly related to MAC severity.
CONCLUSION: The LV ability to contract systolically and diastolically is compromised when MAC is both present and severe. The LV ability to contract systolically and diastolically is likewise impacted by an increase in MAC severity.
À qui profite l’écrit ? Enquête sur le premier libelle contre Marie-Antoinette
Authors: Cossarutto Vincent 
Published: December 2023

À peine montée sur le trône, la jeune Marie-Antoinette est victime d’une brochure diffamatoire, Le Lever de l’aurore , qui marque vivement l’opinion. Généralement considéré comme le premier d’une liste qui ne cessera de s’allonger jusqu’à la Révolution, ce libelle demeure néanmoins enveloppé de mystères, au point que des contemporains doutent de son existence. Le scandale est suffisamment important pour alerter les autorités qui accusent vite le camp Maupeou, alors en passe de quitter Versailles. Toutefois, le jeu des rivalités ministérielles laisse également envisager une manœuvre de Maurepas contre le chancelier. En définitive, l’histoire du premier libelle contre Marie-Antoinette s’inscrit dans un écheveau d’intrigues politiques et révèle, à bien des égards, la force de la rumeur dans l’espace public.
An in-depth study of the biology, trophic ecology and catchability of the invasive pufferfish Lagocephalus sceleratus from southern Turkey, eastern Mediterranean Sea
Authors: Ersönmez Hasan , Enver Özyurt Caner , Mavruk Sinan , Yıldız Taner , Ulman Aylin 
Published: December 2023

The silver-cheeked toadfish (Lagocephalus sceleratus) is an invasive species of highest concern. Its population must be controlled to mitigate its negative impacts on marine ecosystems, fishers, fisheries and human health. This study thoroughly investigates the biology, diet and catchability of the L. sceleratus stock from Finike, Turkey from March 2017 to February 2018 in order to better manage its invasion. A total of 751 specimens were sampled for this study with a M/F ratio of 1.25/1. The species becomes sexually mature at three and a half years of age, and Lm50 was 41.39 cm for males and 42.08 cm for females. Its spawning season in this region was from June to August, peaking in July. Its diet was mostly crustaceans in spring, fish in summer and both fish and crustaceans in winter. This species consumed a large amount of other pufferfish species, resulting in over a quarter of its fish diet. The trophic level of L. sceleratus was 4.41, demonstrating that it is indeed a top predator carnivore in the eastern Mediterranean Sea. Ingested fishing gear parts such as net pieces and hooks were found in about 10% of the fish. A slight modification of longlines using steel branch lines and a swivel hook resulted in double the catch per unit effort than standard longlines, so this technique can be used to target and control more of this invasive species, which is a national priority.
Pour un usage de l’entretien d’explicitation ou micro-phénoménologique avec une interprète de Mohini Attam. Retour sur une recherche en cours
Authors: Fratagnoli Federica 
Published: December 2023

L’article retrace les points clés d’une recherche en cours, soutenue par l’« Aide à la recherche et au patrimoine en danse » du Centre national de la danse (CN D) en 2022. Il interroge l’utilisation d’une technique d’entretien – l’entretien d’explicitation ou micro-phénoménologique – qui a été mobilisé au sein du projet avec une interprète française de Mohini Attam, Brigitte Chataignier. Après avoir situé méthodologiquement ce choix et présenté la technique d’entretien, l’article s’attardera sur la lecture d’un certain nombre d’extraits d’un entretien réalisé avec cette interprète. Ses paroles aideront à comprendre en quoi cette technique permet une verbalisation fine de l’expérience dansée et à avancer des hypothèses sur la place et l’importance de la figure du maître dans ce style de danse.
Analyse empirique de la relation entre le changement climatique et la sécurité alimentaire à la Dominique
Authors: Dupont Louis 
Published: December 2023

Cette étude a pour objectif d’explorer dans le cas de la Dominique, la relation entre la sécurité alimentaire et des variables climatiques et économiques telles que : les précipitations, la température, les émissions de CO2, la croissance économique, et le taux d’inflation. Un modèle autorégressif à retards échelonnés (ARDL) est utilisé à cet effet, pour évaluer l’impact de ces variables sur la sécurité alimentaire, avec des données couvrant la période 1995-2019. Les résultats issus de l’application de ce modèle révèlent qu’à court terme, la température a un impact négatif sur la sécurité alimentaire. Les émissions de CO2 par habitant ont comme attendu un effet négatif à court terme comme à long terme sur la sécurité alimentaire, tandis que la croissance économique exerce un effet positif à long terme sur la sécurité alimentaire. Les précipitations pour leur part affichent un coefficient significativement positif tant qu’à court terme qu’à long terme sur la sécurité alimentaire. Par ailleurs, le coefficient de l’inflation, paradoxalement, n’affiche pas le signe attendu, et n’exerce qu’un effet marginal sur la sécurité alimentaire. Enfin, les évènements climatiques extrêmes tels que les cyclones ont comme prévu des effets néfastes à court terme sur la sécurité alimentaire.
Altérité d’aliénation coloniale. Le drame de la rencontre impossible entre sujets colonisés haïtiens et dominicains
Authors: Renaud Stinfil Jacques 
Published: December 2023

La réalité dichotomique de la situation coloniale, ainsi que l’analyse Fanon, dichotomise également la catégorie de l’altérité. En contexte colonial, il y a l’Autre et l’autre, et entre les deux, une frontière à laquelle sont reliées des violences diverses. L’Autre constitue le pôle négatif de l’indésirable et l’autre, le pôle positif du désirable. En prenant comme cadre d’analyse la relation haïtiano-dominicaine, je montre que ce caractère dichotomique de l’altérité survit dans le monde post-colonial sous la forme pathologique d’une trichotomie altéritaire, en rendant impossible toute rencontre authentique entre sujets aliénés dominicains et haïtiens. Sous l’inspiration de Frantz Fanon, je fais dépendre la solution du problème d’abord d’une initiative d’autoabolition de soi de la part du sujet le plus « concerné », à savoir le sujet noir ou haïtien.
Cutting Edge: PDGF-DD Binding to NKp44 Costimulates TLR9 Signaling and Proinflammatory Cytokine Secretion in Human Plasmacytoid Dendritic Cells
Authors: Barrow Alexander David , Cella Marina , Edeling Melissa Anne , Khan Md. Abdullah-Al-Kamran , Cervantes-Barragan Luisa , Bugatti Mattia , Schmedt Christian , Vermi William , Colonna Marco 
Published: December 2023

Abstract
NKp44 is a human receptor originally found on activated NK cells, group 1 and group 3 innate lymphoid cells that binds dimers of platelet-derived growth factor D (PDGF-DD). NKp44 is also expressed on tissue plasmacytoid dendritic cells (PDCs), but NKp44-PDGF-DD interaction on PDCs remains unstudied. Engagement of NKp44 with PDGF-DD in vitro enhanced PDC secretion of IFN-α, TNF, and IL-6 in response to the TLR9 ligand CpG-ODN, but not TLR7/8 ligands. In tissues, PDCs were found in close contact with PDGF-DD–expressing cells in the high endothelial venules and epithelium of tonsils, melanomas, and skin lesions infected with Molluscum contagiosum. Recombinant PDGF-DD enhanced the serum IFN-α response to systemic HSV-1 infection in a humanized mouse model. We conclude that NKp44 integrates with TLR9 signaling to enhance PDC cytokine production. These findings may have bearings for immune responses to TLR9-based adjuvants, therapy for tumors expressing PDGF-DD, and infections with DNA viruses that induce PDGF-DD expression to enhance viral spread.
Single-Cell Transcriptomes and Immune Repertoires Reveal the Cell State and Molecular Changes in Pemphigus Vulgaris
Authors: Duan Shumin , Li Qionghua , Wang Fei , Kuang Wenjing , Dong Yunmei , Liu Dan , Wang Jiongke , Li Wei , Chen Qianming , Zeng Xin , Li Taiwen 
Published: December 2023

Abstract
The etiology and pathogenesis of pemphigus vulgaris (PV) entail intricate interactions between immune cells and epithelial cells. However, the specific subtypes of immune cells involved in PV, along with their respective roles, remain elusive. Likewise, the precise functions and mechanisms by which glucocorticoids affect cell types within the disease context require further elucidation. To address these knowledge gaps, we performed 5′ single-cell RNA sequencing, combined with V(D)J enrichment on buccal mucosal lesions and peripheral blood samples from treatment-naive patients with PV, in conjunction with post-treatment peripheral blood samples obtained after oral prednisone treatment. Our findings suggest that the IL-1α signaling pathway, myeloid APCs, inflammatory CD8+ resident memory T cells, and dysfunctional CD4+ regulatory T cells are involved in the pathogenesis of PV. Part of these findings were validated by immunohistochemical assays and multiplex immunofluorescence assays. Furthermore, our results highlight the significant impact of prednisone treatment on monocytes and mucosal-associated invariant T cells while revealing a limited effect on CD4+ regulatory T cells. Additionally, we present the CDR3 amino acid sequence of BCR related to PV disease and investigate the characteristics of TCR/BCR clonotypes. In conclusion, our study provides a comprehensive understanding of PV, particularly focusing on the mucosal-dominant type, and sheds light on the effects of glucocorticoids within the PV context. These insights hold promise for the development of new therapeutic strategies in this autoimmune disorder.
Alternatively Spliced Variants of Murine CD247 Influence T Cell Development and Activation, Revealing the Importance of the CD3ζ C-Terminal Region
Authors: Jin Ye , Yuan Huijuan , Mehta Isha , Ezenwa Ogechukwu , Morel Penelope A 
Published: December 2023

Abstract
CD247, also known as CD3ζ, is a crucial signaling molecule that transduces signals delivered by TCR through its three ITAMs. CD3ζ is required for successful thymocyte development. Three additional alternatively spliced variants of murine CD247 have been described, that is, CD3ι, CD3θ, and CD3η, that differ from CD3ζ in the C terminus such that the third ITAM is lost. Previous studies demonstrated defects in T cell development in mice expressing CD3η, but the TCR signaling pathways affected by CD3η and the impacts of the CD3ι and CD3θ on T cell development were not explored. In this study, we used a retrovirus-mediated gene transfer technique to express these three isoforms individually and examined the roles of them on T cell development and activation. Rag1−/− mice reconstituted with CD3θ-expressing bone marrow failed to develop mature T cells. CD3ι-expressing T cells exhibited similar development and activation as cells expressing CD3ζ. In contrast, thymic development was severely impaired in CD3η-reconstituted mice. Single-positive but not double-positive CD3η-expressing thymocytes had reduced TCR expression, and CD5 expression was decreased at the double-positive stage, suggesting a defect in positive selection. Peripheral CD3η-expressing T cells had expanded CD44hi populations and upregulation of exhaustion markers seen by flow cytometry and RNA sequencing analysis. Analysis of early signaling events demonstrated significantly reduced activation of both the PLCγ1 and Akt/mTOR signaling pathways. There was also a reduction in the frequency of activation of CD3η-expressing T cells. These studies reveal the importance of the CD3ζ C-terminal region in T cell development and activation.
Oral Rehydration Beverages for Treating Exercise-Associated Dehydration: A Systematic Review, Part II. The Effectiveness of Alternatives to Carbohydrate-Electrolyte Drinks
Authors: De Brier Niels , Borra Vere , Berry David C. , Zideman David , Singletary Eunice , De Buck Emmy ,   International Liaison Committee on Resuscitation First Aid Task Force
Published: December 2023

Objective
Dehydration associated with exertion is a commonly encountered condition in the first aid setting, particularly at outdoor sporting events. Part I of this systematic review demonstrated that commercial sports drinks can be suggested for effective restoration of fluid balance in dehydrated people. In part II, we perform a systematic review to compare alternative liquids, such as cow’s milk, beer, and coconut water, with water for effective oral rehydration after prolonged exercise.

Data Sources
Cochrane Library, MEDLINE via the PubMed interface, and Embase databases were searched up until June 1, 2022.

Study Selection
Controlled experimental and observational studies involving adults and children were included when dehydration was induced by physical exercise and oral rehydration fluids were administered and compared with regular water. No additional food intake accompanied the rehydration drinks or water. Articles in all languages were included if an English abstract was available.

Data Extraction
Study design, study population, intervention, outcome measures, and study limitations were extracted from each included article.

Data Synthesis
Of 3485 articles screened, 11 articles in which authors compared skim or low-fat cow’s milk, coconut water, or beer (0%–5% alcohol) with water were included. Authors of 4 studies showed that drinking skim or low-fat milk, without additional food intake, led to improved volume/hydration status compared with drinking water. Authors of 3 trials showed no differences at multiple times for outcomes related to volume/hydration status after rehydration with fresh coconut water compared with water. Evidence to recommend beer (0%–5% alcohol) for rehydration is insufficient.

Conclusions
Consuming skim or low-fat cow’s milk without additional food intake as compared with water appears to improve volume/hydration status in people with exercise-induced dehydration. However, evidence is of very low certainty and should be interpreted with caution.
Interest of Oral and Maxillofacial Surgeons Towards Specialised Training in Facial Aesthetic and Plastic Surgery in India - An Evaluative Study
Authors: Kumar Vaibhav , Shome Debraj , Mhatre Pranjal , Khot Atrey J. Pai , Gaunkar Ridhima Birmani , Mhamunkar Priyanka 
Published: December 2023

Abstract

Introduction:
The Dental Council of India has included facial plastic surgery in the scope of practice of Oral and Maxillofacial Surgeons (OMFSs) in India. However, the knowledge and interests of these specialists towards facial plastic surgery are unexplored.

Materials and Methods:
A descriptive cross-sectional study consisting of a structured questionnaire tool with six domains and 46 questions was circulated amongst registered OMFSs in India. The study consisted of 950 participants. The data obtained from this questionnaire were coded and entered into Statistical Package for Social Sciences (SPSS) and a descriptive analysis was conducted.

Results:
The study yielded that only 33% of the participants were completely aware of facial fillers and 30.5% were aware of Botox procedure. However, there was complete awareness of blepharoplasty in 42%, cheiloplasty/palatoplasty in 65.8%, laser facial resurfacing in 23.7% and facial rejuvenation in 23.5% of the participants.

Discussion:
It was found that a high number of OMFSs felt that their exposure to plastic surgery during their post-graduation years was not sufficient.
Rare case of primary neurofibroma involving urinary bladder without signs of neurofibromatosis: An "Oddball" to urologist
Authors: Tadha Ajaykumar Dhirubhai , Gupta Sandeep , Guha Mallick Sinha Mamata 
Published: December 2023

Abstract
Literature related to neurofibroma involving the genitourinary system in a patient with systemic neurofibromatosis-1 (NF-1) is very few. The reported cases further decline in number when it comes to primary neurofibroma of the urinary bladder without signs of NF-1. Here, we report one such case of a 41-year-old gentleman with large bladder mass, presented to us with complaints of obstructive and voiding urinary symptoms with an episode of hematuria. Related imagines were done, and the patient underwent trans-urethral resection of bladder tumor. Histopathology and immunohistochemistry examinations were suggestive of neurofibroma. No recurrence in 6 months of follow-up.
Ambu® aScope™ as a Gastroscope in Emergency Situations: A Report of Two Cases
Authors: Dammalapati Pavan Kumar 
Published: December 2023

Abstract
The working principles of the bronchoscope and gastroscope differ in the fact that the anatomical structures which they interrogate have different collapsibility. The trachea and bronchi are supported by cartilage which make then non-collapsible, hence no external support is needed to visualise their lumen. The oesophagus on the other hand is a collapsible structure which requires air insufflation to investigate the lumen. The modern anaesthesiologist is well versed with the bronchoscopy equipment but is not accustomed to using a gastroscope even though transoesophageal echocardiography is also a modified gastroscope. The proper gastroscopy done by the gastroenterologists or the rigid oesophagoscope needs time and logistical support, which might not be possible every time in the perioperative period. Here, the author tries to demonstrate the use of a flexible bronchoscope (Ambu® aScope™) as a gastroscope in emergencies in the perioperative period.
A successful outcome in a case of nonobstructive azoospermia with repeat surgical sperm retrieval (SSR)-testicular sperm aspiration followed by microsurgical testicular sperm extraction
Authors: Ahuja Meenu Vashisht , Talwar Pankaj 
Published: December 2023

Azoospermia is a major cause of male infertility, either obstructive or nonobstructive azoospermia (NOA). However, such couples should be offered surgical sperm retrieval to enable them to become parents with their own gametes. Cases of NOA will have higher retrieval rate with microsurgical testicular sperm extraction (micro-TESE), even though, in some cases, it may be a repeat procedure.
Presenting here a case of successful twin gestation after intracytoplasmic sperm injection with sperms retrieved successfully by micro-TESE after a previous failed frozen embryo transfer with a very poor retrieval by a testicular sperm aspiration in a case of NOA.
Evaluation of salivary endothelin-1 as a biomarker for oral cancer and precancer
Authors: Irfan Sumaiya , Zaidi Noorin , Tiwari Kshama , Lal Nirupma , Srivastava Anand Narayan , Singh Shivangi 
Published: December 2023

ABSTRACT

Context:
Oral cancer is highly prevalent in India. Lack of awareness and delay in diagnosis and treatment of patients with oral cancer leads to high mortality and poor survival of patients. Salivary endothelin-1 is proposed as a prospective biomarker for oral squamous cell carcinoma.

Aims:
Aim of the study was to evaluate salivary level of endothelin-1 in oral cancer and precancer as a biomarker.

Settings and Design:
We planned a case control study to evaluate salivary level of Endothelin-1 in oral cancer and precancer as a biomarker.

Materials and Methods:
A total of 72 subjects were taken in study out of which 24 cases were of histopathologically confirmed premalignat oral lesion (oral leukoplakia and oral submucous fibrosis), 24 cases were of histopathologically confirmed oral squamous cell carcinoma, and 24 cases of healthy age and gender matched controls without any addiction to tobacco in any form from a tertiary care hospital were taken. Saliva was collected from all following standard guidelines and estimation of salivary endothelin-1 was done by ELISA.

Statistical Analysis Used:
SPSS software version 15.

Results:
Salivary endothelin-1 values of controls ranged between 0.09 and 1.88 pg/ml while that of premalignant cases ranged between 1.16 and 16.135 pg/ml and of SCC cases ranged between 2.567 and 22.98 pg/ml.

Conclusions:
Salivary endothelin-1 is raised in oral squamous cell carcinoma compared to premalignant and controls therefore, shows capability to differentiate between premalignant lesion and oral cancer. So, it could be used as a biomarker for early diagnosis.