bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development and validation of the provider assessed quality of consultations with language interpretation scale (PQC-LI)
Authors: Müller Frank , Ngo Julie , Arnetz Judith E. , Holman Harland T. 
Published: January 2024

Abstract
Objective
With the growing immigrant communities in the western world, there is an urgent need to address language barriers to care, and health disparities as a whole. Studies on limited English proficiency patients (LEP) have focused on patient perspectives of office visits, however little is known about health care provider perspectives of medical visits using interpretive services. We aimed to develop a pragmatic brief questionnaire for assessing providers’ views of the quality of communication in outpatient visits with patients with LEP. The questionnaire was validated in a cross-sectional study (n = 99) using principal component analyses (PCA) with oblimin rotation. Internal consistency was analyzed using Cronbach’s alpha.

Results
Based on theory and literature, a seven-item scale was developed that captures two relevant concepts: (1) Provider - patient interaction during the consultation and (2) perceived quality of translation. The questionnaire was used to assess 99 LEP consultations and demonstrated good feasibility in a clinical setting. PCA revealed the two theory-based components with good factor loadings and internal consistency of α = 0.77. These preliminary results indicate that the questionnaire provides medical professionals with a validated tool to evaluate LEP patient encounters. Further confirmatory validation of the Provider-assessed Quality of Consultations with Language Interpretation (PQC-LI) in larger samples is warranted.
Outcomes of patients with COVID-19 and coronary artery disease and heart failure: findings from the Philippine CORONA study
Authors: Espiritu Adrian I. , Pilapil John Christopher A. , Aherrera Jaime Alfonso M. , Sy Marie Charmaine C. , Anlacan Veeda Michelle M. , Villanueva Emilio Q. III , Jamora Roland Dominic G. 
Published: January 2024

Abstract
Background
Patients with coronavirus disease 2019 (COVID-19) and coronary artery disease (CAD) or heart failure (HF) are more likely to have poor outcomes. This study aimed to determine the characteristics and outcomes of COVID-19 patients with CAD/HF across various institutions in the Philippines.

Methods
We utilized the data from the Philippine CORONA Study and compared the outcomes of admitted COVID-19 patients with CAD/HF versus those without. The Student’s t test, Mann-Whitney U test, binary logistic regression and multivariate regression analysis were utilized. Odds ratios (OR) and Kaplan-Meier curves were generated.

Results
We included a total of 512 patients with COVID-19 had CAD/HF and 10,369 were without. CAD/HF was significantly associated with COVID severity, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization. After adjusting for confounders, the presence of CAD/HF was still associated with death from a cardiac cause (OR 2.22, 95% CI 1.49–3.3, p < 0.01).

Conclusions
The presence of CAD or HF was significantly associated with severity of COVID disease, all-cause mortality, death from cardiac causes, respiratory failure, and prolonged hospitalization.
The association between social camouflage and mental health among autistic people in Japan and the UK: a cross-cultural study
Authors: Oshima Fumiyo , Takahashi Toru , Tamura Masaki , Guan Siqing , Seto Mikuko , Hull Laura , Mandy William , Tsuchiya Kenji , Shimizu Eiji 
Published: January 2024

Abstract
Background
To examine the relationship between social camouflage and mental health in Japanese autistic adults and make an international comparison with a sample from the UK.

Methods
This study analysed secondary data of participants with a self-reported diagnosis of autism from Japan (N = 210; 123 men and 87 women) and the UK (N = 305; 181 women, 104, men, and 18 nonbinary). The relationships between the quadratic term of the Camouflaging Autistic Traits Questionnaire and mental health scales, including depression and anxiety, were assessed.

Results
The UK sample showed linear relationships, whereas the Japanese sample showed significant nonlinear relationships. The quadratic terms of the Camouflaging Autistic Traits Questionnaire slightly explained generalised anxiety (β = .168, p = .007), depression (β = .121, p = .045), and well-being (β = − .127, p = .028). However, they did not explain the association between social anxiety and the Camouflaging Autistic Traits Questionnaire.

Limitations
Participants had self-reported diagnoses, and while the autism-spectrum quotient provides a cut-off value for screening, it does not enable confirming diagnoses. Mean scores of the Japanese version of the Camouflaging Autistic Traits Questionnaire were lower as compared to the original CAT-Q, which implies that the social camouflage strategy types used by autistic people in Japan and the UK could differ. The cross-sectional design limits causal inferences.

Conclusion
In the UK, more social camouflage was associated with poorer mental health scores, whereas too little or too much social camouflage was associated with a low mental health score in Japan. The Japanese population is seemingly less aware of and educated on autistic characteristics and considers ‘average’ behaviour a good thing. This could influence Japanese autistic people’s social camouflage use, differing from that of autistic people in the UK. The differences in the relationship between social camouflage and mental health between Japan and the UK could be associated with national-level divergence regarding the culture of autism.
ABYOLOv4: improved YOLOv4 human object detection based on enhanced multi-scale feature fusion
Authors: Li Rui , Zeng Xin , Yang Shiqiang , Li Qi , Yan An , Li Dexin 
Published: January 2024

AbstractThe purpose of human object detection is to obtain the number of people and their position in images, which is one of the core problems in the field of machine vision. However, the high missing detection rate from small- and medium-sized human bodies due to the large variety of human scale in human object detection tasks still influences the performance of human object detection. To solve the above problem, this paper proposed an improved ASPP_BiFPN_YOLOv4 (ABYOLOv4) method to detect human object detection. In detail, Atrous Spatial Pyramid Pooling (ASPP) module was used to replace the original Spatial Pyramid Pooling module to increase the receptive field level of the network and improve the perception ability of multi-scale targets. Then, the original Path Aggregation Network (PANet) multi-scale fusion module was replaced by the self-built bi-layer bidirectional feature pyramid network (Bi-FPN). Meanwhile, a new feature was imported into the proposed model to reuse the mid- and low-level features, which could enhance the ability of the network to express the characteristics of small- and medium-sized targets. Finally, the standard convolution in Bi-FPN was replaced by depth-separable convolution to make the network achieve the balance of accuracy and the number of parameters. To identify the performance of the proposed ABYOLOv4 model, the human object detection experiment is carried out by using the public data set of VOC2007 and VOC2012, the improved YOLOv4 algorithm is 0.5% higher than the original AP algorithm, and the weight file size of the model is reduced by 45.3 M. The experimental results demonstrated that the proposed ABYOLOv4 network has higher accuracy and lower computational cost for human target detection.
Implementation of highly isolation OLR: based microstrip full-duplex Tx/Rx antenna systems with low insertion loss for contemporary wireless system applications
Authors: Elabd Rania H. , Hussein Amr H. , Mousa Marwa E. , A.Kabeel Ahmed 
Published: January 2024

AbstractThis paper presents a Highly Isolation open-loop resonators (OLR)—based microstrip full-duplex Tx/Rx antenna systems with low insertion loss for contemporary wireless system applications. Through a T-junction combiner, the proposed diplexer is accomplished by combining two OLR—based band-pass filters tuned at two distinct frequencies. The system is implemented on a Rogers TMM4 substrate with a loss tangent of 0.002, a dielectric constant of 4.7, and a thickness of 1.52 mm. The suggested full duplex has dimensions of (90 × 70) mm2. It achieves a modest frequency space ratio ofR = 0.1646 in both transmit and receive modes by having two resonance frequencies of$${f}_{t}$$ft= 2.191 GHz and$${f}_{r}$$fr= 2.584 GHz, respectively. The simulated structure displays good insertion losses (IL) of approximately 1.2 dB and 1.79 dB for the two channels, respectively, at fractional bandwidths of 1.24% at 2.191 GHz and 0.636% at 2.584 GHz. The simulated isolation values for 2.191 GHz and 2.584 GHz are 53.3 dB and 66.5 dB, respectively.
Barriers and facilitators to the HPV vaccine: a multicenter qualitative study of French general practitioners
Authors: Tron Arthur , Schlegel Vincent , Pinot Juliette , BRUEL Sébastien , Ecollan Marie , Bel Josselin Le , Rossignol Louise , Gauchet Aurélie , Gagneux-Brunon Amandine , Mueller Judith , Banaszuk Anne-Sophie , Thilly Nathalie , Gilberg Serge , Partouche Henri 
Published: January 2024

Abstract
Background
In France, human papillomavirus (HPV) vaccination coverage is low, with 30.7% of 17-year-old girls having received a complete HPV vaccination schedule in 2020.

Aim
To determine the perspective and behaviors of general practitioners (GPs) regarding HPV vaccination with their patients and if a reluctance is observed.

Design and setting
A qualitative study based on semi-directed individual interviews was conducted between December 2019 and December 2020. A representative sample of GPs with various profiles were included in 4 French regions.

Method
A purposive sampling was used and interviews were continued until data saturation was reached. The analysis was based on the grounded theory.

Results
Twenty-six GPs aged 29–66 years were interviewed. The measures taken by the French health authorities (lowering the target age, reimbursing the vaccine, extending the target population to boys) were perceived as facilitators. The reported barriers were organizational, due to low attendance of adolescents, and relational, mainly due to parental vaccine hesitancy. Physicians had to deal with fears about the perceived risks and concerns about sexuality conveyed by HPV vaccination and linked to the socio-cultural characteristics of the families. Physicians developed strategies, including scientific knowledge mobilization, empowerment of families by promoting health through prevention, repetition of the vaccination proposals, personal experience and relationship. Different practices were identified according to three GP typologies: effective, convinced but unpersuasive, and reluctant physicians.

Conclusion
Based on these results, specific interventions, including communication techniques, especially for hesitant or unpersuasive physicians, are needed to enable GPs to become more effective.
The relationship between loneliness and problematic social media usage in Chinese university students: a longitudinal study
Authors: Wu Peibo , Feng Rong , Zhang Jindan 
Published: January 2024

Abstract
Background
A significant number of cross-sectional studies have explored the correlation between loneliness and problematic social media use. However, the causal relationship between these two key variables remains controversial, and the developmental relationship over time is unclear.

Methods
We conducted a one-year longitudinal study with 538 Chinese college students using questionnaires and employing cross-lagged and latent growth models to investigate the causal relationship and developmental dynamics between loneliness and problematic social media use.

Results
The results indicate that (a) loneliness and problematic social media use mutually and positively influence each other, establishing a bidirectional causal relationship; (b) Chinese college students experience a gradual increase in levels of loneliness and problematic social media use during their time in college; and (c) the intercept and slope of loneliness significantly and positively affect the intercept and slope of problematic social media use, and conversely, the intercept and slope of problematic social media use significantly and positively influence the intercept and slope of loneliness.

Conclusion
These findings reveal the longitudinal relationship between loneliness and problematic social media use among Chinese college students and offer insights for researchers and educators to intervene in college students' loneliness and problematic social media use from a developmental perspective.
Anther-derived microspore embryogenesis in pepper hybrids orobelle and Bomby
Authors: Sahana K. P. , Srivastava Arpita , Khar Anil , Jain Neelu , Jain P. K. , Bharti Hemlata , Harun Mohd , Mangal Manisha 
Published: January 2024

Abstract
Background
Traditional breeding methods have long been employed worldwide for the evaluation and development of pepper cultivars. However, these methods necessitate multiple generations of screening, line development, evaluation, recognition, and crossing to obtain highly homozygous lines. In contrast, in vitro anther-derived microspore culture represents a rapid method to generate homozygous lines within a single generation. In the present study, we have optimized a protocol for microspore embryogenesis from anther cultures of pepper hybrids Orobelle and Bomby.

Results
We achieved early and successful embryo formation from both genotypes by subjecting the buds to a cold pretreatment at 4 °C for 4 days. Our optimized culture medium, comprised of MS medium supplemented with 4 mg/L NAA, 1 mg/L BAP, 0.25% activated charcoal, 2.6 g/L gelrite, 30 g/L sucrose, and 15 mg/L silver nitrate, exhibited the highest efficiency in embryo formation (1.85% and 1.46%) for Orobelle and Bomby, respectively. Furthermore, successful plant regeneration from the anther derived microspore embryos was accomplished using half-strength MS medium fortified with 2% sucrose and 0.1 mg/L 6-benzylaminopurine (BA), solidified with 2.6 g/L gelrite. The ploidy status of the microspore-derived plantlets was analyzed using flow cytometry technique. Notably, the haploid plants exhibited distinct characteristics such as reduced plant height, leaf length, leaf width, and shorter internode length when compared to their diploid counterparts derived from seeds.

Conclusion
Our findings highlight the potential of anther culture and microspore embryogenesis as an advanced method for accelerating pepper breeding programs, enabling the rapid production of superior homozygous lines.
Comparative effectiveness of pelvic floor muscle training, mirabegron, and trospium among older women with urgency urinary incontinence and high fall risk: a feasibility randomized clinical study
Authors: Fisher Steve R. , Villasante-Tezanos Alejandro , Allen Lindsay M. , Pappadis Monique R. , Kilic Gokhan 
Published: January 2024

Abstract
Background
Untreated, urgency urinary incontinence (UUI) and overactive bladder (OAB) can precipitate a vicious cycle of decreasing physical activity, social isolation, fear of falling, and falls. Structured behavioral interventions and medications are common initial treatment options, but they elicit their effects through very different mechanisms of action that may influence fall-related outcomes differently. This study will determine the feasibility of conducting a comparative effectiveness, three-arm, mixed methods, randomized clinical trial of a behaviorally based pelvic floor muscle training (PFMT) intervention versus two recent drug options in older women with UUI or OAB who are also at increased risk of falling.

Methods
Forty-eight women 60 years and older with UUI or OAB who screen positive for increased fall risk will be recruited through the urogynacology and pelvic health clinics of our university health system. Participants will be randomly assigned to one of three 12-week treatment arms: (1) a course of behavioral and pelvic floor muscle training (PFMT) provided by physical therapists; (2) the beta-3 agonist, mirabegron; and (3) the antimuscarinic, trospium chloride. Study feasibility will be established through objective metrics of evaluability, adherence to the interventions, and attrition. We will also assess relevant measures of OAB symptom severity, quality of life, physical activity, incident falls, and concern about falling.

Discussion
The proposed research seeks to ultimately determine if linkages between reduction in UI symptoms through treatment also reduce the risk of falling in this patient population.

Trial registration
NCT05880862. Registered on 30 May 2023.
Optimizing juice extraction in sugar mills: application of time delay compensation with intelligent controllers
Authors: Saidahmed Mohamed T. F. , Attiya Ibrahim Ahmed M. , Elkilany Basma Gh. 
Published: January 2024

AbstractThe juice extraction process plays a crucial role in the sugar production industry, but it often faces challenges due to time delays that can negatively impact efficiency and quality. This paper introduces a Time Delay Compensation (TDC) technique aimed at mitigating this issue. The TDC technique is specifically designed to minimize the adverse effects of time delays, thereby improving control performance. The primary objective of this research is to enhance the efficiency and quality of the juice extraction process, ultimately leading to increased productivity and profitability for sugar mills. To achieve this goal, we conducted an extensive review of existing solutions, highlighting their limitations and associated challenges. In response, we propose a unique and practical solution that can be implemented using MATLAB Processes. Through simulation results, we demonstrate the effectiveness of the TDC technique in suppressing time delay and enhancing control performance, resulting in a significant improvement in extraction efficiency. This work contributes to the field of sugar production by introducing a specialized TDC technique tailored for the juice extraction process in sugar mills.
Study of serum calprotectin level in rheumatoid arthritis: unexpected low level and possible explanations
Authors: El-Tawab Sarah Sayed , Moharram Lamya Mohamed , Younis Gihan Abdellatif , EL Dabah Nermeen Ahmed , Adel-Naby Hoda Mohamed 
Published: January 2024

Abstract
Background
Assessment of disease activity in rheumatoid arthritis (RA) is crucial to optimize the response to treatment and prevent radiographic progression. DAS28 is the most commonly used disease activity index, which incorporates either erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP). Several studies showed that using ESR and/or CRP in assessing disease activity falls short of detecting a significant portion of patients with active disease. Calprotectin (CLP) is an interesting protein that was found to be a promising biomarker of disease activity in RA patients’ sera when CRP is normal. This study aimed to measure serum CLP level in 50 RA patients with different grades of disease activity and compare its level with age- and sex-matched control.

Results
In this case–control study, the mean serum CLP level was significantly lower in RA patients (25.94 ± 25.87 ng/ml) compared to the control group values (53.02 ± 77.93 ng/ml), p < 0.001. The measured serum CLP in RA patients was lower than its level in other published studies. No significant difference was found between patients with different disease activity grades in the serum CLP level (H = 4.28, p = 0.23). Serum samples were collected and stored from RA patients over 4 months and from the control subjects over 1.5 months and were stored at –80 °C until analysis was performed according to the manufacturer’s instruction.

Conclusion
The low level of serum CLP among RA patients is most probably due to proteolysis related to storage conditions. Pre-analytic factors like the type of blood sample, whether the sample is fresh or frozen, and duration of storage exert an effect on serum CLP level when measured by enzyme-linked immunosorbent assay.
Positive thinking about negative studies
Authors: Petkova Eva , Ciarleglio Adam , Casey Patricia , Poole Norman , Kaufman Kenneth , Lawrie Stephen M. , Malhi Gin , Siddiqi Najma , Bhui Kamaldeep , Lee William 
Published: January 2024

SummaryThe non-reporting of negative studies results in a scientific record that is incomplete, one-sided and misleading. The consequences of this range from inappropriate initiation of further studies that might put participants at unnecessary risk to treatment guidelines that may be in error, thus compromising day-to-day clinical practice.
Antiviral Therapy Utilization and 10-Year Outcomes in Resected Hepatitis B Virus– and Hepatitis C Virus–Related Hepatocellular Carcinoma
Authors: Huang Daniel Q. , Hoang Joseph K. , Kamal Rubayet , Tsai Pei-Chien , Toyoda Hidenori , Yeh Ming-Lun , Yasuda Satoshi , Leong Jennifer , Maeda Mayumi , Huang Chung-Feng , Won Jun Dae , Ishigami Masatoshi , Tanaka Yasuhito , Uojima Haruki , Ogawa Eiichi , Abe Hiroshi , Hsu Yao-Chun , Tseng Cheng-Hao , Alsudaney Manaf , Yang Ju Dong , Yoshimaru Yoko , Suzuki Takanori , Liu Joanne K. , Landis Charles , Dai Chia-Yen , Huang Jee-Fu , Chuang Wan-Long , Schwartz Myron , Dan Yock Young , Esquivel Carlos , Bonham Andrew , Yu Ming-Lung , Nguyen Mindie H. 
Published: January 2024

PURPOSE There are limited data on antiviral treatment utilization and its impact on long-term outcomes of hepatitis B virus (HBV)– and hepatitis C virus (HCV)–related hepatocellular carcinoma (HCC) after hepatic resection. We aimed to determine the utilization and impact of antivirals in HBV- and HCV-related HCC. METHODS This cohort study included 1,906 participants (1,054 HBV-related HCC and 852 HCV-related HCC) from 12 international sites. All participants had HBV- or HCV-related HCC and underwent curative surgical resection. The primary outcome was the utilization of antiviral therapy, and the secondary outcome was long-term overall survival (OS). RESULTS The mean (±standard deviation [SD]) age was 62.1 (±11.3) years, 74% were male, and 84% were Asian. A total of 47% of the total cohort received antiviral therapy during a mean (±SD) follow-up of 5.0 (±4.3) years. The overall antiviral utilization for participants with HBV-related HCC was 57% and declined over time, from 65% before 2010, to 60% from 2010 to 2015, to 47% beyond 2015, P < .0001. The overall utilization of antivirals for HCV-related HCC was 35% and increased over time, from 24% before 2015 to 74% from 2015 and beyond, P < .0001. The 10-year OS was lower in untreated participants for both HBV (58% v 61%) and HCV participants (38% v 82%; both P < .0001). On multivariable Cox regression analysis adjusted for relevant confounders, antiviral therapy initiated before or within 6 months of HCC diagnosis was independently associated with lower mortality in both HBV- (adjusted hazard ratio [aHR], 0.60 [95% CI, 0.43 to 0.83]; P = .002) and HCV-related HCC (aHR, 0.18 [95% CI, 0.11 to 0.31]; P < .0001). CONCLUSION Antiviral therapy is associated with long-term survival in people with HBV- or HCV-related HCC who undergo curative resection but is severely underutilized.