bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using Gut Microbiome as A Tool in Dietary Intervention for Prevention and Management of Obesity
Authors: Tamilvanan Janani , Kalpana Chinnappan. A. 
Published: November 2023

The gut microbiome has trillions of bacteria which play an important role in human health and disease. Several animal and human studies have shown that dysbiosis, microbial imbalance as the causative factor in obesity and metabolic syndrome. Significant research evidence demonstrates that changes in the proportion of Bacteroidetes and Firmicutes has been associated with obesity, but this has been recently challenged. Similar studies were carried out in several populations, however, there are no such studies, to date, among Asian Indians. We aimed to examine the usefulness of gut microbiome testing in developing personalized diet for managing obesity. In this study, we selected individuals, generally healthy, free- living adults, both men and women with BMI 25- 40 kg/m2 and with previous history of failures at weight loss who visited a Weight Loss Clinic, based in Coimbatore, India & were offered a gut microbiome test. We included 54 individuals in the intervention group who received personalized dietary advice for weight loss based on the gut microbiome test and another set of 52 individuals visiting the same clinic were included in the comparison group based on their age, height, weight and BMI who received generic diet. A statistically significant increase in the Bacteroidetes genus was observed in the personalized nutrition group (p = .04). The change (delta) values in gut microbiome composition in personalized nutrition group were significantly higher at the end of 120 days. Gut microbiome-based personalized microbiome modulation through diet significantly improves gut microbiome profiles among obese individuals. We would further need studies with larger sample size to validate these study findings and long-term follow-up are needed.
Clinical Characteristics and Glycaemic Control in Adults Living with Type 1 Diabetes: A 1-Year Retrospective Chart Review at Two South African Public Sector Tertiary Hospitals
Authors: Poobalan Naidoo , Bruno Pauly , Ebrahim Variava , Somasundram Pillay , Zaheer Bayat , Reyna Daya , Michelle Carrihill , Kiolan Naidoo , Lauren Sekhuthe , Sindeep Bhana 
Published: November 2023

Abstract

Background: An estimated 11.8% of the South African population are living with diabetes. There is a paucity of data related to the clinical characteristics and glycaemic control in people living with T1DM within the South African public healthcare sector.

Objective: To describe the clinical characteristics and glycaemic control of people living with T1DM in a public health care setting.

Methods: The study was an observational study conducted at two tertiary public sector hospitals in South Africa by means of a chart review. The study involved adults living with T1DM treated with human insulin for 12 months prior to the date of informed consent.

Results: A total of 224 patients with T1DM were enrolled, with 190 (84.8%) from Chris Hani Baragwanath Academic Hospital and 34 (15.2%) from Klerksdorp Tshepong Hospital Complex. One patient withdrew consent, leaving a total analysed population of 223. Of the 223 patients, 37 (16.6%) were controlled (most recent glycosylated haemoglobin (HbA1c) < 7%) while the remainder 186 (83.4%) were uncontrolled (most recent HbA1c ≥ 7%). The mean age of the study group was 33 ± 9 years. The majority of participants were female (122 [54.7%]) and of black ethnicity (215 [96.4%]). The mean number of hypoglycaemic events per patient-year was 151.4 (SD ± 213.9). Diabetic ketoacidosis occurred more frequently in the uncontrolled group.

Conclusion: The majority of patients in this study did not achieve target HbA1c, placing them at higher risk for long-term diabetes complications. Poor glycaemic control, leading to long term complications, as well as hypoglycaemia and diabetic ketoacidosis adds further strain to the resource constrained public healthcare in South Africa.
Comparison of Chronic Rheumatic Mitral Regurgitation Severity between Cardiac Magnetic Resonance Imaging and Echocardiography
Authors: Meel Ruchika , Peters Ferande , Libhaber Elena , Nethononda Richard 
Published: November 2023

Abstract

Background and Purpose

Traditionally, echocardiography has been used for assessing mitral regurgitation (MR) severity. However, existing qualitative, semi-quantitative and quantitative parameters suffer from several limitations. The shortcomings of the current echocardiographic methods for MR severity assessment are especially pronounced in the context of eccentric MR jets. Cardiac magnetic resonance (CMR) imaging is useful for assessing valvular lesions as it is now the gold standard for assessing left ventricular and left atrial volumes. Therefore, we sought to study and compare echocardiography with CMR for assessment of chronic rheumatic MR severity.

Methods

Twenty-two patients with chronic rheumatic MR who underwent both CMR and echocardiography were studied. For the echocardiography part of the study, the MR severity was assessed as per current guidelines. The CMR measurements were performed per standard guidelines by a single operator experienced in this technique.

Results

The mean age of the study population was 36.3±13.9 years and 81% were females. There was overall poor agreement for the assessment of MR severity using the quantitative parameters for MR assessment between echocardiography and CMR. Although the measurements for end diastolic volume index (EDVi), end systolic volume index (ESVi), regurgitant volume (RV) and regurgitant fraction (RF) showed moderate correlation, these parameters displayed poor agreement between the two tests. We noted discrepant findings in terms of classification of valve lesion severity in seven patients. Six patients were reclassified after CMR to severe MR and one to moderate MR based on quantitative parameters of regurgitant volume (RV) and regurgitant fraction (RF).

Conclusion

In patients with severe chronic rheumatic MR with eccentric jets, when MR quantification by echocardiography is inadequate, CMR derived quantitative volumetric parameters may be useful for accurate classification of the severity of mitral regurgitation.
Prosedur Perolehan Hak Pakai di atas Tanah Hak Milik Menurut Hukum Tanah Nasional untuk Menjamin Kepastian Hukum bagi Orang Asing [Procedure to Obtain Right of Use of Freehold Land According to National Land Law to Guarantee Legal Certainty for Foreigners]
Authors: Christie Gracia , Merlim Valerie , Widjojo Anne Gunadi Martono 
Published: November 2023

<p><em>Indonesia has a prohibition on ownership of freehold land by foreigners. Foreign citizens who are domiciled in Indonesia and want to obtain land rights can obtain a right of use with a period of time. This research's purpose is to analyze procedure for foreigners to obtain Right of Use of freehold land with time limitation in Indonesia, and the role of Land Deed Official (PPAT) in the making of the deed of Right of Use of freehold land with time limitation. This research is empirical normative research with data from literature study and interviews. Type of approach that used in this research is systematic of law. Foreign citizens domiciled in Indonesia can have a Right of Use with a period of time on freehold land must fulfill the requirements and procedures in accordance with Indonesian laws and regulations. This is to ensure the achievement of legal certainty. In the acquisition of the right of use on freehold land, the role of the land deed official as a public official authorized to make deeds for the acquisition of the right of use on freehold land is necessary. Unfortunately, in practice there are still land deed officials who do not follow the procedures of Right of Use in accordance with the laws and regulations.</em></p><p><strong><br /></strong></p><p><strong>Bahasa Indonesia Abstrak: </strong>Di Indonesia terdapat larangan kepemilikan tanah Hak Milik oleh orang asing. Warga Negara Asing yang berkedudukan di Indonesia dan ingin memperoleh Hak Atas Tanah dapat memperoleh Hak Pakai dengan jangka waktu. Penelitian ini bertujuan untuk menganalisis prosedur bagi WNA untuk memperoleh Hak Pakai di atas tanah Hak Milik dengan jangka waktu di Indonesia, serta peran Pejabat Pembuat Akta Tanah (PPAT) dalam pembuatan Akta atas Hak Pakai di atas tanah hak milik dengan jangka waktu tertentu. Penelitian ini adalah penelitian normatif empiris dengan data yang diperoleh dari studi kepustakaan dan wawancara. Jenis pendekatan dalam penelitian ini adalah pendekatan sistematika hukum. Warga Negara Asing yang berkedudukan di Indonesia dapat mempunyai hak pakai dengan jangka waktu di atas tanah hak milik harus memenuhi syarat dan prosedur sesuai peraturan perundang-undangan Indonesia. Hal itu dilakukan agar tercapainya kepastian hukum. Dalam perolehan hak pakai di atas tanah hak milik perlu adanya peran Pejabat Pembuat Akta Tanah sebagai pejabat umum yang diberikan kewenangan untuk membuat akta guna perolehan hak pakai di atas tanah hak milik. Tetapi sangat disayangkan, dalam praktik masih ada Pejabat Pembuat Akta Tanah yang tidak mengikuti prosedur hak pakai sesuai peraturan perundang-undangan.</p>
Tanggung Jawab Notaris Terhadap Akta Autentik yang Dibuat Tanpa Dihadiri Pihak Penghadap [Notary’s Responsibilities of Authentic Deed not Made in the Presence of the Party]
Authors: Thomas Thomas 
Published: November 2023

<p><em>An authentic deed is a perfect piece of evidence, which means that an authentic deed has physical, formal and material evidentiary power in accordance with the provisions based on Article 1886 of the Civil Code. Notaries play an important role in the process of making an authentic deed, the provisions of which are regulated in general law as well as the code of ethics attached to Notaries. However, sometimes when making an authentic deed, various problems are often found in the preparation process, one of which is the carrying out of the authentic deed without the presence of the party present. This research intends to examine the responsibilities and legal consequences of this problem. This research is normative juridical research using secondary data through statue approach</em> <em>case approach</em><em>. It was found that the Notary violated the Law of Notary Position, has a number of responsibilities, and authentic deeds made under such conditions also have legal consequences that are detrimental to the parties to the deed.</em></p><p><strong><em> </em></strong></p><p><strong>Bahasa Indonesia Abstrak: </strong>Akta autentik merupakan suatu alat bukti yang sempurna yang artinya akta autentik memiliki kekuatan pembuktian secara lahiriah, formal dan materiil sesuai ketentuan berdasarkan Pasal 1886 KUH Perdata. Notaris berperan penting dalam proses pembuatan suatu akta autentik yang mana ketentuannya diatur dalam undang-undang secara umum begitu juga dengan kode etik yang melekat terhadap Notaris. Namun terkadang dalam pembuatan akta autentik sering ditemukan berbagai masalah dalam proses penyusunannya, salah satunya adalah dengan dilaksanakannya pembuatan akta autentik tanpa dihadiri pihak penghadap. Penelitian ini bermaksud untuk menelaah mengenai tanggung jawab dan akibat hukum atas masalah tersebut. Penelitian ini adalah penelitian yuridis normatif dengan menggunakan data sekunder melalui pendekatan undang-undang dan pendekatan kasus. Ditemukan bahwa Notaris melanggar UUJN, memiliki sejumlah tanggung jawab, dan terhadap akta autentik yang dibuat dengan kondisi demikian juga memiliki akibat hukum yang merugikan para pihak dalam akta tersebut.</p>
Excesso de óbitos classificados com códigos garbage na pandemia de Covid-19, no estado da Paraíba
Authors: Araújo da Silva Everlane Suane , Antonio Alves de Araujo Matheus 
Published: November 2023

No cenário de calamidade assistido durante a pandemia de Covid-19, o ato de definir a causa básica de um óbito não foi trivial e o aumento da utilização dos códigos garbage (códigos mal definidos ou pouco específicos) traz preocupação em relação à qualidade da informação sobre as causas de morte nos estados do Brasil. Constatou-se um aumento significativo do número de óbitos no período pandêmico no estado da Paraíba, localizado na região Nordeste do Brasil, situação que se assemelhou ao contexto nacional. Em 2020 ocorreram 31.107 óbitos na Paraíba, enquanto no período de 2015 a 2019 foi identificada uma média de 27.000 óbitos. O objetivo do presente estudo é identificar e mensurar o excesso de óbitos classificados com códigos garbage em 2020, no estado da Paraíba, durante a pandemia de Covid-19. As séries temporais de óbitos foram obtidas do Painel de Monitoramento da Mortalidade por Causas Básicas Inespecíficas ou Incompletas (garbage codes) do Ministério da Saúde, para todos os meses de 2015 a 2020. Foram calculadas as projeções de óbitos totais e dos óbitos por códigos garbage (CG). O cálculo do excesso da proporção de óbitos classificados por códigos garbage no estado da Paraíba, em 2020, resultou em 8,58%, destacando-se o mês de junho com o maior valor (19,42%). Espera-se contribuir para avanços no conhecimento da realidade da qualidade da informação da notificação dos óbitos em uma área do país que almeja avanços nesse sentido e evidenciar a necessidade da investigação em outras localidades do Brasil.
Efektivitas Pelatihan Menggunakan Moodle Sinkronus Asinkronus Untuk Meningkatkan Pemahaman Implementasi Kurikulum Merdeka Pada Guru SD
Authors: Khairiyah Ummu , Retnaningsih Lina Eka , Masruroh Masruroh , Haryono Heny Ekawati 
Published: November 2023

<em>Program Sekolah Penggerak (PSP) is one of the effort made by the government to realize the vision on Indonesian education to become advanced, sovereign, independent, have a personality and create a profile of Pancasila students. Through the driving school program, several activities were carried out, one of which was an online Learning Committee Training (PKP) which was attended by principals and teachers for 10 days using a moodle with an asynchronous synchronous approach. In this study, it will be emphasized whether using a synchronous asynchronous approach is effective in understanding the implementation of an independent curriculum as indicated by the results of the pre-test and post-test. The research subjects used were 18 people consisting of 6 principals and 12 elemetary school teacher from 6 different schools. The result obtained, it was found that the training using the asynchronous synchronous approach was effective in increasing understanding about the implementation of the independent curriculum in elementary schools.</em>
Implementation of Project-based Learning Model to Increase Creativity of Fifth Grade Students at 1st Ledok Salatiga Elementary School
Authors: Wibowo Luth Prasandi Eko , Winanto Adi 
Published: November 2023

<p><em>Creativity is needed to face challenges in the digital era and industrial revolution 4.0. This research aims to increase the creativity of students through the Project-based Learning (PjBL) model. The type of research is classroom action research. This study consisted of pre-cycle and two cycles. Each cycle carried out the stages of action planning, action implementation, observation, and reflection. The subjects of this study were 21 students in fifth grade at 1<sup>st</sup> Ledok Salatiga Elementary School. Instruments used in data collection by observation sheets and creativity tests. Data analysis uses an interactive model consisting of data condensation, data presentation, and drawing conclusions. The indicator of this research is an increase in the average value of creativity of at least 85%. The results showed that the acquisition of a creativity score in pre-cycle was 41% (low category), creativity in cycle I obtained 61.5% (moderate category) and in cycle II increased creativity obtained 85% (high category). It can be concluded that the implementation of the PjBL model can increase the creativity of fifth grade students at 1<sup>st</sup> Ledok Salatiga Elementary School.</em></p>
Pengaruh Bahan Ajar Ragam Tulis Terintegrasi Berbasis Multiliterasi Terhadap Kemampuan Kemampuan Berpikir Tingkat Tinggi
Authors: Adiredja Rajji K. , Hartati Tatat , Riyana Cepi 
Published: November 2023

Kemampuan literasi dan multiliterasi yang rendah serta tujuan pembelajaran di sekolah untuk melatihkan kemampuan KBTT, sehingga perlu untuk menerapkan bahan ajar berbasis kemampuan kemampuan tersebut. Penelitian ini bertujuan untuk menganalisis dan mendeskripsikan Pengaruh Bahan Ajar Ragam Tulis Terintegrasi Berbasis Keterampilan Berfikir Tingkat Tinggi dan Multiliterasi Terhadap Kemampuan Berpikir Tingkat Tinggi. Peneliti menggunakan pendekatan kuantitatif dengan metode penelitian eksperimen dan Desain penelitian yang digunakan adalah One Group Pretest-Posttest Design (desain kelompok tunggal dengan pretest dan posttest). Subjek penelitian adalah siswa kelas V SDN 5 Regol, SDN 2 Karangmulya, dan SDN 2 Pameungpeuk. Teknik pengumpulan data yang digunakan adalah tes. Hasil penelitian menunjukan ada pengaruh bahan ajar ragam tulis terintegrasi berbasis keterampilan berfikir tingkat tinggi dan multiliterasi terhadap kemampuan kemampuan berpikir tingkat tinggi yang dibuktikan dengan adanya peningkatan skor pada hasil posttest siswa. Berdasarkan hasil perhitungan dengan rumus statistic uji t menggunakan SPSS menunjukkan bahwa Sig. (2 tailed) = 0,000 &lt; 0,05 ,maka Ho ditolak dan Ha diterima hipotesis menyatakan bahwa ada perbedaan hasil KBTT antara sebelum dan sesudah diberikan bahan ajar. Berdasarkan analisis data tersebut dapat dikatakan bahwa ada perbedaan yang signifikan KBTT anak antara sebelum dan sesudah diberi bahan ajar. Sehingga dapat disimpulkan ada pengaruh bahan ajar terhadap KBTT.
Analisis Implementasi Manajemen Kelas Dalam Pembelajaran Siswa Kelas V di MIN 4 Sragen Tahun Ajaran 2021/2022
Authors: Maharani Melisa Anggun , Chamdani Muhamad , Wahyudi Wahyudi 
Published: November 2023

Tujuan penelitian ini bertujuan untuk mendeskripsikan (1) pelaksanaan pembelajaran, (2) implementasi manajemen kelas, dan (3) menganalisis faktor yang mempengaruhi manajemen kelas dalam pembelajaran. Penelitian ini merupakan penelitian kualitatif dan kuantitatif dengan metode <em>mixed methods</em>. Subjek penelitian adalah kepala sekolah, guru dan siswa kelas V MIN 4 Sragen. Data yang digunakan berupa data kualitatif dan kuantitatif. Teknik pengumpulan data menggunakan observasi dan wawancara. Validitas data menggunakan triangulasi sumber dan teknik. Analisis data dilaksanakan melalui reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan bahwa: (1) pelaksanaan pembelajaran yang telah dilaksanakan berada pada kategori sangat layak (81%-100%) sesuai dengan indikator RPP dan pelaksanaan pembelajaran , (2) Implementasi Manajemen Kelas yang telah dilaksnakan berada pada kategori sangat layak layak (81%-100%) sesuai dengan indikator manajemen kelas. dan (3) Implementasi manajemen kelas dalam pembelajaran berdampak pada siswa yaitu dapat memahami materi pembelajaran dengan baik dan memiliki sikap positif. Namun, terdapat kendala dalam implementasi manajemen kelas dalam pembelajaran di MIN 4 Sragen dan dioptimalkan dengan upaya yang sesuai dengan permasalahan tersebut. Implementasi manajemen kelas dalam pembelajaran dengan baik maka akan berdampak positif terhadap pembelajaran.
Penerapan Pendekatan Blended Learning untuk Meningkatkan Hasil Belajar IPA Tentang Kalor dan Perpindahannya Pada Siswa Kelas V SD Negeri 5 Kutosari Tahun Ajaran 2021/2022
Authors: Arrifa'i Khasanudin , Rokhmaniyah Rokhmaniyah , Hidayah Ratna 
Published: November 2023

Tujuan penelitian ini adalah meningkatkan hasil belajar IPA tentang kalor dan Perpindahannya pada siswa kelas V melalui penerapan pendekatan <em>Blended Learning</em>. Penelitian tindakan kelas ini dilaksanakan dalam tiga siklus. Subjek penelitian ialah guru dan siswa kelas V SD Negeri 5 Kutosari. Data yang digunakan berupa data kualitatif dan kuantitatif. Teknik pengumpulan data menggunakan observasi, wawancara, dan tes. Validitas data menggunakan triangulasi sumber dan teknik. Analisis data dilaksanakan melalui reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan terjadi peningkatan pembelajaran IPA tentang kalor dan perpindahannya dengan pendekatan <em>Blended Laerning</em>, persentase ketuntasan hasil belajar siswa siklus I sebesar 90%, pada siklus II sebesar 91,66%, dan pada siklus III sebesar 93,33%. Dapat disimpulkan bahwa penerapan pendekatan <em>Blended Learning</em> dapat meningkatkan hasil belajar IPA tentang kalor dan perpindahannya pada siswa kelas V SD Negeri 5 Kutosari tahun ajaran 2021/2022.
Peningkatan Keaktifan dan Hasil Belajar IPAS Menggunakan Model Problem Based Learning Kelas IV SD Muhammadiyah Kleco 2 Tahun Ajaran 2022/2023
Authors: Hastiwi Fina , Khasanah Uswatun , Wahyuningsih Sri 
Published: November 2023

Penelitian ini didasarkan untuk mengembangkan model pembelajaran yang mendorong partisipasi aktif peserta didik dan meningkatkan pemahaman konsep materi IPAS. Keaktifan peserta didik merupakan faktor penting yang berpengaruh pada peningkatan hasil belajar. Penelitian ini bertujuan untuk meningkatkan keaktifan dan hasil belajar menggunakan model <em>Problem Based Learning</em>. Jenis penelitian tindakan kelas dilakukan dua siklus masing-masing siklus dua kali pertemuan. Analisis data melalui tahapan reduksi data, penyajian, kesimpulan. Metode penelitian melalui observasi, wawancara, dan analisis hasil belajar. Keaktifan dinilai berdasarkan partisipasi dalam diskusi, kemampuan berpikir kritis, dan kerjasama dalam kelompok. Hasil belajar diukur melalui tes. Hasil penelitian menunjukkan tahap prasiklus persentase keaktifan yaitu 50%, siklus I sebesar 63% dan meningkat pada siklus II mencapai 83%. Peningkatan hasil belajar tahap prasiklus 40,74%, siklus I sebesar 53,69% dan siklus II mencapai 81,33%. Hasil yang diperoleh menunjukkan ketercapaian indikator keberhasilan dengan kategori sangat baik. Kesimpulannya bahwa penggunaan model PBL dapat meningkatkan keaktifan dan hasil belajar IPAS.