bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential Seismic Hazard in Seoul, South Korea: A Comprehensive Analysis of Geology, Seismic, and Geophysical Field Observations, Historical Earthquakes, and Strong Ground Motions
Authors: Kim Byeongwoo , Hong Tae-Kyung , Lee Junhyung , Park Seongjun , Lee Jeongin 
Published: October 2023

ABSTRACT
A series of moderate-size (Mw 4.0–6.0) earthquakes occurred in South Korea after the 2011 Mw 9.0 Tohoku–Oki megathrust earthquake, incurring public concern about possible occurrence of devastating earthquakes in Seoul—the capital city of South Korea, where historical seismic damage was reported. The seismicity is distributed in Seoul, being dominated by strike-slip earthquakes. The fault planes are oriented in north-northeast–south-southwest, which is a favorable direction to respond to the ambient stress field. Higher rates of seismicity are observed in the northwestern Seoul at depths of &lt;10 km. Micro-to-small earthquakes occur episodically in the central Seoul along the Chugaryeong fault system that traverses Seoul in north–south. Seismic, geophysical, and geological properties illuminate the fault structures. Stochastic modeling of ground motions reproduces the seismic damages of historical earthquakes reasonably, supporting the occurrence of devastating historical earthquakes in Seoul. The seismicity distribution, focal mechanism solutions, geological features, and seismic and geophysical properties suggest the possible presence of earthquake-spawning blind faults in Seoul. The peak ground motions are assessed for moderate-size scenario earthquakes (Mw 5.4 with focal depth of 7 km) at six representative subregions in Seoul. The upper bounds of peak ground accelerations reach ∼11  m/s2. The seismic damage potentials for moderate-size earthquakes are high in most areas of Seoul, particularly around river sides covered by alluvium.
Antagonism Pseudomonas diminuta on The Growth of Vibrio harveyi with Mix Culture Method
Authors: Hastuti Satyantini, Ir., M.Si Dr. Woro , Mubarak Ahmad Syahrul , Subekti Sri 
Published: October 2023

One of the obstacles often encountered in white shrimp farming is the presence of bacterial diseases caused by Vibrio group bacteria. One of the efforts to control Vibriosis is by using antagonistic bacteria as biocontrol agents, one of which is using Pseudomonas diminuta. In this study Pseudomonas diminuta and Vibrio harveyi were co-cultured with the aim of determining the optimal density and effective incubation time of P. diminuta which could provide the highest inhibition of V. harveyi growth. This study used a completely randomized design with six treatments P0 (P. diminuta 105 CFU/ml), P1 (V. harveyi 106 CFU/ml), P2 (P. diminuta 105 CFU/ml+V. harveyi 106 CFU/ml), P3 (P. diminuta 106 CFU/ml+V. harveyi 106 CFU/ml), P4 (P. diminuta 107 CFU/ml+V. harveyi 106 CFU/ml), P5 (P. diminuta 108 CFU/ml+V. harveyi 106 CFU/ml). The results of this study showed that P2, P3, P4 and P5 had decreased growth of V. harveyi when compared to control P1 (V.harveyi 106 CFU/ml). The decrease in the growth of V. harveyi occurred at the 8th to 48th hour. V. harveyi in P3 (2.72 × 108 CFU/ml), P2 (2.80 × 108 CFU/ml), P4 (2.96 × 108 CFU/ml) and P5 (2.90 × 108 CFU/ml) at the 48th hour of incubation was lower than P1 (3, 15×108 CFU/ml). Based on the results of the Duncan test showed that P2, P3, P4 and P5 were significantly different (p <0.05) from P1. From this study it was concluded that administration of P. diminuta at a density of 106 CFU/ml was able to reduce the growth of V. harveyi. The greatest decrease in the growth of V. harveyi occurred at the 48th hour.
Analysis of the Dynamics of Tick-Borne Encephalitis Incidence and the Number of People who Appealed to Medical Organizations about Tick Bites in the European North of Russia
Authors: Tronin A. A. , Tokarevich N. K. , Buzinov R. V. , Sokolova O. V. , Gnativ B. R. , Bubnova L. A. , Safonova O. S. 
Published: October 2023

In recent decades, a significant increase in the incidence of tick-borne viral encephalitis (TBVE) and the number of people attacked by ticks has been recorded in the European North of Russia.The aim of the study was to analyze the dynamics of the TBVE incidence and the number of people who appealed to medical organizations regarding tick bites in the European North of Russia.Materials and methods. We used the Form No. 2 “Information on infectious and parasitic diseases”, the results of operational seasonal monitoring of TBVE, presented by the Rospotrebnadzor Administrations of the respective territories for our study. Statistical data processing was performed using the Microsoft Excel program. Display of the results on the map was carried out in the geographic information system ESRI ArcMap.Results and discussion. Combined analysis of the data on the number of cases and TBVE incidence, the number of people who appealed to medical organizations about tick bites and the number of people seeking advice about tick bites per 100 thousand population for the Arkhangelsk Region, the Republics of Karelia and Komi and their municipal districts has been performed. The mean values and gradients of the number of cases, incidence (2010–2020), the number of people who appealed to medical organizations regarding tick bites, and the number of people seeking treatment for tick bites per 100 000 population (2002–2020) have been calculated; maps of average values and gradients constructed. The incidence and the number of cases remain at the high level, exceeding the national average, but have been declining in the last decade. The number of people who appealed to medical organizations and the appealability of the population about tick bites per 100 000 of the population remain at a consistently high level and show no downward trend. The incidence and appealability of the population due to tick bites per 100 thousand of the population is spreading in a northerly direction, covering new territories in the Arctic zone. The main driving force behind the observed epidemic situation in the European North of Russia is the natural processes of climate change.
Prevalence of Markers of Certain Blood-Borne Viral Infections in Pregnant Women and Their Partners in the Republic of Guinea
Authors: Balde T.A. L. , Ostankova Yu. V. , Boumbaly S. , Valutite D. E. , Davydenko V. S. , Shchemelev A. N. , Shchemelev E. N. , Zueva E. B. , Anufrieva E. V. , Astapchik E. V. , Arbuzova O. V. , Skvoroda V. V. , Vasil’eva D. A. , Esaulenko E. V. , Semenov A. V. , Totolian Areg A. 
Published: October 2023

The aim of the work was to estimate the prevalence of HIV, HBV and HCV markers among pregnant women and their male partners in the Republic of Guinea.Materials and methods. The material of the study was blood plasma samples from 140 pregnant women living in Kindia prefecture and N’Zerekore prefecture, as well as 60 male partners who reported sexual contact with HIV-infected persons. The samples were examined for the presence of serological (HBsAg, HBeAg, antibodies anti-HBs IgG, anti-HBcore IgG, anti-HBe IgG, anti-HCV IgG, Ag/Ab-HIV) and molecular (HBV DNA, HCV RNA, HIV RNA) markers.Results and discussion. The age of the examined pregnant women ranged from 13 to 55 years and was on average (26.29±9.67) years. The age of men varied from 15 to 60 years, on average – (29.05±11.99) years. When assessing the prevalence of serological markers, antibodies to HCV were detected in 2.14 % cases in women and in 3.33 % cases in men. Antibodies to HIV were found in 6.43 % and 6.67 % women and men, respectively. Serological markers associated with HBV were detected in 80.71 % (HBsAg – 13.57 %) of women and 81.67 % (15 %) of men. In the pregnant women, HCV RNA was not detected, HIV RNA was revealed in 1 case, HBV DNA was identified in 26 cases (18.57 %), including 5 % HBsAg-negative hepatitis B cases. In the men group, HCV RNA and HIV RNA were detected in 3.33 % and 6.67 % cases, respectively. HBV DNA was determined in 16.67 % of men, including latent hepatitis B in one person. A significantly higher incidence of HIV in men compared to women is shown (χ2=3.907 at p<0.05). The relative risk of HIV infection in men is nine times higher than in women: RR=9.333; p=0.0291; 95 % CI: 1.065–81.815 %. Four out of five identified HIV infection cases were co-infected with HBV and/or HCV. There is an obvious need to introduce screening for HIV, HCV, HBV, including latent hepatitis B, into routine laboratory diagnostics during examination of pregnant women and their partners, followed by couples counseling and vaccination against hepatitis B virus.
Serum Ferritin as a Novel Predictive Marker for Breast Cancer Metastasis and Correlation with Metastasis-Associated Burden
Authors: Yao Xufeng , Sha Hezhang , He Xiang , Gan Lu , Wang Xiaoyi , CHENG Qiao 
Published: October 2023

Abstract
Background: Breast cancer became the most common cancer worldwide, Early detection of metastatic events is vital for improving survival. Currently, the serum tumor markers for monitoring metastatic breast cancer in clinic practice are carbohydrate antinegen (CA15-3) and carcinoembryonic antigen (CEA) based on the 2007 edition of American Society of Clinical Oncology (ASCO) guidelines. More specific, sensitive, and cost-effective tumor markers need to be identified to improve the accuracy of predicting distant metastasis of breast cancer.
Methods: A total of 468 breast cancer patients including 170 patients with distant metastasis and 298 without metastasis were retrospectively reviewed. The levels of the serum tumor markers ferritin, CA15-3, and CEA in both the metastasis and non-metastasis groups, in subgroups of different pathologic types, different metastatic sites and different tumor burden were analyzed via One-way analysis of variance and the receiver operating characteristics (ROC) curve. compare the differences between ROC curves using paired comparison method.
Results: High levels of serum ferritin predict distant metastasis of breast cancer with the highest specificity and sensitivity among all the three markers, especially in HR−/HER2+ and HR−/HER2− molecular subtypes. The prediction accuracy for metastasis increased when a combination of two or all three markers, and the combination of ferritin and CA15-3 could be the optimal choice to maximize the efficiency and predictive ability for metastasis. The baseline levels of all the three markers were associated with metastasis tumor burden and could be more sensitive in predicting patients with liver metastasis than patients with lung and bone metastases.
Conclusions: the findings obtained from this study suggest that serum ferritin is a putative candidate to be a non-invasive biomarker for monitoring breast cancer metastasis which is even more sensitive and specific than the traditional breast tumor markers CA153 and CEA. However, further studies including a larger set of patient data are needed to validate the conclusions
Viral activation and ecological restructuring characterize a microbiome axis of spaceflight-associated immune activation
Authors: Mason Christopher , Tierney Braden , Kim JangKeun , Overbey Eliah , Ryon Krista , Foox Jonathan , Sierra Maria , Bhattacharya Chandrima , Damle Namita , Najjar Deena , Park Jiwoon , Medina J. Sebastian Garcia , Houerbi Nadia , Meydan Cem , Hirschberg Jeremy , Qiu Jake , Kleinman Ashley , Al-Ghalith Gabriel , MacKay Matthew , Afshin Evan , Dhir Raja , Borg Joseph , Gatt Christine , Brereton Nicholas , Readhead Ben , Beyaz Semir , Venkateswaran Kasthuri , Blease Kelly , Moreno Juan , Boddicker Andrew , Zhao Junhua , Lajoie Bryan , Scott Ryan , Altomare Andrew , Kruglyak Semyon , Levy Shawn , Church George 
Published: October 2023

Abstract

Maintenance of astronaut health during spaceflight will require monitoring and potentially modulating their microbiomes, which play a role in some space-derived health disorders. However, documenting the response of microbiota to spaceflight has been difficult thus far due to mission constraints that lead to limited sampling. Here, we executed a six-month longitudinal study centered on a three-day flight to quantify the high-resolution microbiome response to spaceflight. Via paired metagenomics and metatranscriptomics alongside single immune profiling, we resolved a microbiome “architecture” of spaceflight characterized by time-dependent and taxonomically divergent microbiome alterations across 750 samples and ten body sites. We observed pan-phyletic viral activation and signs of persistent changes that, in the oral microbiome, yielded plaque-associated pathobionts with strong associations to immune cell gene expression. Further, we found enrichments of microbial genes associated with antibiotic production, toxin-antitoxin systems, and stress response enriched universally across the body sites. We also used strain-level tracking to measure the potential propagation of microbial species from the crew members to each other and the environment, identifying microbes that were prone to seed the capsule surface and move between the crew. Finally, we identified associations between microbiome and host immune cell shifts, proposing both a microbiome axis of immune changes during flight as well as the sources of some of those changes. In summary, these datasets and methods reveal connections between crew immunology, the microbiome, and their likely drivers and lay the groundwork for future microbiome studies of spaceflight.
Effects of Emotional and Cognitive Changes on Aesthetic Evaluation of Poetry Based on Subjective and Physiological Continuous Responses with Pupil Diameter Measurement
Authors: Hitsuwari Jimpei , Nomura Michio 
Published: October 2023

Abstract

Haiku poetry, a short poem with a clear form, has the potential to elucidate many unknown aspects of linguistic art. Previous studies on haiku appreciation have shown that negative emotion and cognitive ambiguity reduce aesthetic evaluation. Considering the importance of negative emotions and ambiguity in art, it is beneficial to clarify the process of emotional and cognitive changes during aesthetic evaluation. This study examined the temporal effects of emotional and cognitive changes on aesthetic evaluation from multiple perspectives by measuring the ratings of each section of haiku, continuous emotional reports, and physiological changes in pupil diameter. The 112 students first rated the haiku at three time points on items such as beauty, valence, and ambiguity. Next, they rated the same haiku continuously for 20 seconds using a joystick for valence and arousal during which the pupil diameter was measured. The results showed that a decrease in negative emotions and ambiguity explained the beauty of the haiku. In the continuous emotion reports, positive emotions gradually increased for positive haiku and negative emotions gradually increased for negative haiku, while arousal decreased once and then gradually increased for both forms of haiku. Additionally, an increase in pupil diameter also explained the beauty. The roles of negative emotions and ambiguity were revealed by focusing on both subjective and physiological indicators of emotional and cognitive changes during haiku appreciation. This study has contributed to the advancement of our understanding of linguistic art forms by empirically exploring conscious and unconscious emotional and cognitive responses to haiku.
Genetic changes influence behavioral shifts of brown bears in response to human-dominated landscapes in Eastern Türkiye
Authors: Aytekin Mübeccel Çisel Kemahlı , Kusak Josip , Chynoweth Mark , Çoban Emrah , Çoban Ayşegül , Naderi Morteza , Kavaklı İbrahim Halil , Şekercioğlu Çağan Hakkı , Sağlam İsmail Kudret 
Published: October 2023

Abstract

Large carnivores are known for altering their life-history strategies in response to environmental change. One such shift was recently discovered in Eurasian brown bears (Ursus arctos arctos) in Sarıkamış, Eastern Türkiye where an open city garbage dump has led to the emergence of two distinct life strategists: sedentary bears that use the city dump as a primary food source and migratory bears that avoid the dump and migrate in search of food. Understanding the genetic processes that have led to the establishment of these strategies is vital for predicting the overall impact of anthropogenic pressures on brown bears forced to live in human-dominated landscapes. To this end, we determined the amounts of genetic and adaptive variation associated with these two life-history strategies using genome-wide data obtained from 31 bears fitted with satellite collars and tracked for an average of one year. We found that the Eastern Türkiye brown bear population is genetically highly differentiated and isolated from other world populations but nevertheless contains high genetic diversity and mixed ancestry. We identified genomic regions and distinct genotypes associated with sedentary and migratory behavior and high differentiation between behavioral groups at these loci. Outlier loci were associated with several genes related to transcriptional modification, including a key SNP within the first exon of CCRL2 that regulates immune response. Collectively, our results present the first test of the genetic basis of behavioral shifts that may be playing an important role in the ongoing adaptation of Eastern Türkiye brown bears to human-dominated landscapes, emphasizing the importance of evolutionary genomics for understanding how species survive and adapt to global change.
Association between social support and short-term cardiac readmission: a double-center study
Authors: Sabri Mahshad , Emami Sepideh , Eskandari Ramin , Fakher Mahsa 
Published: October 2023

Abstract

Introduction:
Coronary artery disease is among the most common causes of mortality worldwide. Prior studies in the field have mostly focused on biological risk factors, and the effects of psychosocial risk factors and their mechanisms of action are not yet well- known; studies in women-only patient populations are also scant. Therefore, in this study, we aimed to assess psychosocial risk factors in a patient population of women to better clarify the roles of these factors in coronary artery disease.
Methods
One hundred seventeen women with coronary artery disease were included in this cross-sectional study and were asked to complete the social support questionnaire and interviewed for their baseline characteristics (including age, level of education, occupational status, marital status, previous cardiac admission, history of hypertension, diabetes and smoking) between 2022 and 2023. Their total social support scores and their scores in each of the social support fields were calculated, and their correlations with other factors were analyzed statistically.
Results
The mean age of the participants was 61,37 ± 10 years. The mean social support score was 76.83 ± 13.31. There was a significant correlation between tangible support scores and being married (P = 0.012). We also found a significant association between readmission rates and affectionate support (P = 0.037), with scores being slightly higher in patients who were readmitted during follow-up. Associations between previous history of cardiac hospitalization, hypertension, diabetes, past or current smoking, age, level of education, occupational status and BMI were not significant.
Conclusions
Being married significantly increases perceived tangible social support. We also found slightly higher but significant affectionate social support scores in patients who were readmitted during follow-up. Given the differences in outcomes between cross-sectional and cohort studies, more cohort studies with longitudinal designs and extensive follow-up periods are needed to clarify the effects and mechanisms of action of social support in the incidence and prognosis of coronary artery disease.
Molecular Testing for Gastrointestinal Pathogens in Intestinal Tissue of Infants with Necrotizing Enterocolitis or Spontaneous Intestinal Perforation
Authors: Talavera-Barber Maria , Sanchez Pablo , Conces Miriam , Kaptsan Irina , Everhart Kathy , Leber Amy , Malleske Daniel , Moallem Mohannad , Panesso-Gomez Santiago , Shimamura Masako 
Published: October 2023

Abstract

Objective
The objective of this study was to determine the frequency of common gastrointestinal bacterial, parasitic, and viral pathogens in necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP) -associated intestinal tissue.
Study Design:
Retrospective cohort study examined formalin fixed, paraffin embedded (FFPE) surgical or autopsy intestinal tissue from NEC or SIP specimens. DNA and RNA were extracted and analyzed by multiplex PCR panel (GIFA Biofire). DNA or RNA from stool samples containing each pathogen were extracted for positive controls.
Results
193 intestinal tissue samples were available from 310 infants (156 NEC, 37 SIP). Six (3%) infants with stage III NEC tested positive for a target pathogen; 2, C. difficile; 3, Enteroaggregtive E. coli; and 1, Giardia. No gastrointestinal viral pathogens were detected.
Conclusion
Molecular testing yielded few GI pathogens suggesting that these organisms are likely not major causes of NEC or SIP.
Boundary violations and well-being on teleworkers: recovery’s role and gender differences
Authors: Mascarenhas Madalena , Carvalho Vânia Sofia , Moretto Cleide Fátima , Chambel Maria José 
Published: October 2023

Abstract
Background
This study aimed to explore the role of psychological detachment from work in the relationship of boundary violations and flourishing, as well as gender differences. We developed and tested a moderate mediation model where psychological detachment was the explanatory mechanism of the relationship between boundary violations with flourishing and using gender as the moderating variable.
Methods
A cross-sectional study was conducted with a sample of 921 teleworking university professors (mean age 44 years) in Brazil in June 2020. Multigroup analysis and moderate mediation were performed using Mplus 7.2.
Results
Psychological detachment mediates the effects of boundary violations (in both direction) in flourishing and that work-to-family violations are more harmful to women’s recovery instead as family-to-work violations are more harmful to men’s recovery.
Conclusion
The main contributions of this study are the importance of recovery in the subjective well-being of teleworkers and the relationship between boundary violations and gender.