bluuebunny/crossref_metadata_2025_split huggingface dataset:
Industrial‐Level Paired Electrosynthesis of Valuable Chemicals over a High‐Performance Heterostructural Electrode
Authors: Zhou Guorong , Cheng Han , Wu Yilin , Tong Yun , Dai Ruihao , Zhu Jiaye , Zheng Xiaonan , Lin Cong , Chen Pengzuo , Wu Changzheng 
Published: February 2025

AbstractPaired electrosynthetic technology is of significance to realize the co‐production of high‐added value chemicals. However, exploiting efficient bifunctional electrocatalyst of the concurrent electrocatalysis to achieve the industrial‐level performance is still challenging. Herein, an amorphous Co2P@MoOx heterostructure is rationally designed by in situ electrodeposition strategy, which is acted as excellent bifunctional catalysts for the electrocatalytic nitrite reduction reaction (NO2RR) and glycerol oxidation reaction (GOR). The membrane‐electrode assembly (MEA) electrolyzer realizes a low voltage of 1.30 V, robust stability over 200 h at 100 mA cm−2, high Faraday efficiencies and yield of NH3 (above 95 %, 49.7 mg h−1 cm−2) and formate (above 95 %, 304.4 mg h−1 cm−2) at industrial‐level current density of 500 mA cm−2. In situ spectroscopy studies have shown that high‐valence CoOOH is the main active material of GOR, and the main catalytic conversion pathway of NO2RR involves key *NH2OH reaction intermediates. In addition, theoretical calculations confirm that the Co2P@MoOx heterostructure has strong interfacial electronic interaction and optimized reaction energy barriers, which endows its intrinsically high electrocatalytic activity for the co‐electrosynthesis of NH3 and formate.
Biochar from crop residues mitigates N2O emissions and increases carbon content in tropical soils
Authors: Gabetto Fernanda Palmeira , Tenelli Sarah , Netto‐Ferreira Julia Barra , Martins Junior Joaquim , Almeida Octávio Augusto Costa , Cosenza Marcela Lamas , Strauss Mathias , Carvalho João Luis Nunes 
Published: February 2025

AbstractThe application of biochar may offer a cost‐effective solution to decrease nitrous oxide (N2O) emissions in agriculture soils while having the potential to enhance soil carbon (C) accumulation. Biochar can be produced primarily from a range of agricultural and woody residual biomass, potentially resulting in biochar types with distinct properties. This study evaluated the effects of four different biochar types on soil N2O emissions, C storage, and diversity of the soil microbial community in a tropical environment. A greenhouse experiment with sugarcane plants was conducted with six treatments: soil only (CTR); soil + N fertilizer (NF); NF + sugarcane straw biochar (NF+SB); NF + sugarcane bagasse biochar (NF+BB); NF + Pinus residue biochar (NF+PB); and NF + eucalyptus residue biochar (NF+EB). Regardless of the origin of the feedstock, all biochar reduced the cumulative N2O emissions by 25% to 50% in comparison with the nitrogen‐fertilized treatment. Only NF+EB registered higher N2O emissions than NF+SB. The feedstock material also influenced the chemical properties of biochar, showing a negative correlation between oxidized functional groups and N2O emissions. Variations in the physicochemical properties of biochar did not affect soil C levels or microbial diversity, as all treatments with biochar presented similar results. All biochar types increased soil C levels, but only those derived from wood residues showed higher C content than CTR and NF. Despite biochar having no effects on overall soil microbiome diversity, the amendment tended to increase the abundance of Bacteroidetes and Proteobacteria, while suppressing the ammonia‐oxidizing phylum Thaumarchaeota. Biochar application had no significant effect on ammonium availability; however, it exhibited the capacity to retain nitrate. The application of biochar in tropical soils can therefore be considered a nature‐based solution to decrease N2O emissions and increase C levels without changing microbial diversity.
Recent Advances in Achieving High Energy/Power Density of Lithium–Sulfur Batteries for Current and Near‐Future Applications
Authors: Heo Junyoung , Gu Hawon , Lee Changhee , Sung Junghwan , Kim Dong‐Hee , Han Jiye , Oh Yeong‐Seok , Ahn Seongki , Jeon Il , Park Jun‐Woo 
Published: February 2025

ABSTRACTAlthough lithium–sulfur batteries (LSBs) are promising next‐generation secondary batteries, their mass commercialization has not yet been achieved primarily owing to critical issues such as the “shuttle effect” of soluble lithium polysulfides (LiPSs) and uncontrollable Li dendrite growth. Thus, most reviews on LSBs are focused on strategies for inhibiting shuttle behavior and achieving dendrite‐free LSBs to improve the cycle life and Coulombic efficiency of LSBs. However, LSBs have various promising advantages, including an ultrahigh energy density (2600 Wh kg−1), cost‐effectiveness, environmental friendliness, low weight, and flexible attributes, which suggest the feasibility of their current and near‐future practical applications in fields that require these characteristics, irrespective of their moderate lifespan. Here, for the first time, challenges impeding the current and near‐future applications of LSBs are comprehensively addressed. In particular, the latest progress and novel materials based on their electrochemical characteristics are summarized, with a focus on the gravimetric/volumetric energy density (capacity), loading mass and sulfur content in cathodes, electrolyte‐to‐sulfur ratios, rate capability, and maximization of these advantageous characteristics for applications in specific areas. Additionally, potential areas for practical applications of LSBs are suggested, with insights for improving LSB performances from a different standpoint and facilitating their integration into various application domains.
Citrus Flavonoids as Antimicrobials
Authors: Ciriminna Rosaria , Petri Giovanna Li , Angellotti Giuseppe , Luque Rafael , Fabiano-Tixier Anne-Sylvie , Meneguzzo Francesco , Pagliaro Mario 
Published: February 2025

Citrus flavonoids are highly bioactive compounds exerting numerous health benefits including anticancer, antioxidant, antimicrobial, anti‐inflammatory, mitoprotective and neuroprotective activity. Research on their broad‐scope bioactivity experienced a renaissance in the early 2000s and further accelerated after COVID‐19, including research on their antimicrobial properties. Summarizing selected research achievements on the antimicrobial activity of the main Citrus flavonoids, this study aims to provide a unified picture on the antimicrobial properties of these valued compounds that will hopefully assist in the development of flavonoid‐based antimicrobials, including antibacterial treatments suitable for clinical use minimizing antimicrobial resistance.
Serial Change and Clinical Impact of Irregular Protrusion in Lesions With Chronic Coronary Syndrome
Authors: Okamoto Naotaka , Mizote Isamu , Ishihara Takayuki , Nakamura Daisuke , Shiraki Tatsusya , Itaya Naoki , Tsujimura Takuya , Takahara Mitsuyoshi , Hikosou Shungo , Mano Toshiaki , Ueno Takahumi , Nishino Masami , Nanto Shinsuke , Sakata Yasushi 
Published: February 2025

ABSTRACTBackgroundThe changes over time and effects on long‐term clinical outcomes beyond 1 year of irregular protrusion (IP) in chronic coronary syndrome (CCS) remains unclear.AimsThis study aimed to assess the time‐dependent change and long‐term clinical impact of IP in CCS lesions.MethodsThis study was a post hoc analysis of COLLABORATION study, which was a multicenter, prospective, observational study conducted from July 2018 to February 2020, assessing 1‐ and 12‐month serial vessel responses after stent implantation using OCT and coronary angioscopy. Time‐dependent change in the presence of IP was evaluated using the serial OCT examinations. The cumulative 3‐year incidence of TLR was compared between the lesions with and without IP, as well as between those with and without residual IP at 1 month.ResultsAmong 107 lesions, IP was detected in post‐OCT pullbacks in 38 (35.5%) lesions. Out of the 38 lesions, IP remained in 9 (23.7%) lesions at 1 month and existed in 2 (5.3%) lesions at 12 months. The cumulative 3‐year incidence of TLR was significantly higher in IP group than in non‐IP group (13.6% vs. 3.0%, p = 0.04). Similarly, it was significantly higher in lesions with residual IP at 1 month than those without (33.3% vs. 4.3%, p < 0.01). All residual IP at 1 month were composed of angioscopic yellow plaques and red thrombi.ConclusionsThe presence of IP decreased over time, but approximately one‐fourth of IP remained at 1 month. IP and residual IP at 1 month were important post‐stent OCT findings leading to long‐term TLR in patients with CCS.
Long‐Term Impact of Early Subclinical Leaflet Thrombosis After Transcatheter Aortic Valve Implantation
Authors: Iwata Juri , Hayashida Kentaro , Arita Ryo , Moriizumi Tomonari , Kajino Akiyoshi , Sakata Shingo , Ryuzaki Toshinobu , Shinada Keitaro , Tsuruta Hikaru , Yamada Yoshitake , Kato Jungo , Takahashi Tatsuo , Yamazaki Masataka , Jinzaki Masahiro , Shimizu Hideyuki , Ieda Masaki 
Published: February 2025

ABSTRACTBackgroundHypoattenuated leaflet thickening (HALT) after transcatheter aortic valve implantation (TAVI) detected on multidetector computed tomography (MDCT) is considered leaflet thrombosis. However, its impact on long‐term clinical outcomes remains unclear. This study aimed to investigate the impact of early HALT detection after TAVI on long‐term clinical outcomes and structural valve deterioration beyond 6 years.MethodsOf the 672 consecutive patients who underwent TAVI between 2013 and 2018, 448 were treated with either SAPIEN XT or SAPIEN 3 and underwent MDCT analysis within 30 days after TAVI. MDCT results and echocardiographic data were analyzed annually.ResultsHALT was detected in 68 (15.2%) of 448 eligible patients within 30 days after TAVI. No significant difference in effective orifice area was observed by echocardiography within 30 days after TAVI between the HALT and the non‐HALT groups in SAPIEN XT (HALT vs. non‐HALT: 1.62 ± 0.66 cm2 vs. 1.72 ± 0.43 cm2; p = 0.26) and in SAPIEN 3 (1.42 ± 0.35 cm2 vs. 1.45 ± 0.34 cm2; p = 0.63). No significant differences in all‐cause mortality (52.9% vs. 60.0%; hazard ratio (HR): 1.19; 95% confidence interval (CI): 0.83−1.70; p = 0.3), stroke incidence (5.9% vs. 7.1%; HR: 1.06; 95% CI: 0.08−13.7; p = 0.97), heart failure rehospitalization (10.3% vs. 15.0%; HR: 2.3; 95% CI: 0.89−5.99; p = 0.09), and structural valve deterioration (14.7% vs. 17.9%; HR: 0.89; 95% CI: 0.45−1.73; p = 0.73) were observed between the HALT and the non‐HALT groups during the median follow‐up of 1872 (interquartile range; 1203−2468) days.ConclusionsHALT within 30 days was not associated with clinical outcomes or hemodynamic performance during long‐term follow‐up.
Impact of Side Branch Occlusion on Patient Outcomes After Bifurcation Percutaneous Coronary Intervention
Authors: Strepkos Dimitrios , Alexandrou Michaella , Mutlu Deniz , Carvalho Pedro E. P. , Ser Ozgur S. , Jalli Sandeep , Voudris Konstantinos , Burke M. Nicholas , Sandoval Yader , Brilakis Emmanouil S. 
Published: February 2025

ABSTRACTBackgroundThe outcomes and characteristics of patients with side branch occlusion (SBO) after bifurcation percutaneous coronary intervention (PCI) have received limited study.MethodsWe compared the procedural characteristics and outcomes of patients with and without SBO among 933 provisional bifurcation PCIs performed in 803 patients at six centers between 2014 and 2024.ResultsThe prevalence of SBO was 13% (n = 121). SBO patients had lower rates of hypertension, prior coronary artery bypass graft surgery (CABG), and prior PCI but higher angiographic complexity, with higher prevalence of left anterior descending artery stenoses, smaller side branch diameter and more severe side branch diameter stenoses. SBO patients were more likely to convert from provisional to two‐stent strategies (24.8% vs 6.0%, p < 0.001), and to require plaque modification (39.7% vs 17.5%, p < 0.001) and side branch percutaneous transluminal coronary angioplasty (PTCA) (25.6% vs 12.9%, p < 0.001). SBO patients had lower technical (78.5% vs 96.2%, p < 0.001) and procedural (73.5% vs 92.2%, p < 0.001) success and similar in‐hospital major adverse cardiovascular events (MACE), but higher dissection rates (7.1% vs 2.0%, p = 0.007). Patients with untreated SBO had similar in‐hospital MACE with untreated SBO patients. During a median follow‐up of 1,095 days patients with treated SBO (83.9%, n = 94) had lower follow‐up MACE (hazard ratio [HR]: 0.29, 95% confidence intervals [CI]: 0.10, 0.84, p = 0.023) and mortality (HR: 0.22, CI: 0.065, 0.755, p = 0.016) compared with patients with untreated SBO.ConclusionsSBO occurs in 13% of provisional PCIs. SBO patients had more complex coronary lesions and worse follow‐up clinical outcomes if the SBO was left untreated.
Unified Protocol vs Mentalization‐Based Therapy for Adolescents With Borderline Personality Disorder: A Randomized Controlled Trial
Authors: Mohajerin Banafsheh , Gallagher Matthew W. , Howard Richard 
Published: February 2025

ABSTRACTBackgroundDespite several treatments, e.g., mentalization‐based therapy (MBT) and Unified Protocol (UP), being adapted to treat adolescents with borderline personality disorder (BPD), there exists a dearth of literature regarding their relative efficacy. In this study modified forms of MBT and UP – MBT‐A and UP‐A respectively—were compared in their ability to reduce borderline symptoms in a sample of 91 Iranian adolescents (two‐thirds female) with a BPD diagnosis.MethodsIndividuals randomly allocated to one of two treatment groups, MBT‐A (N = 45) or UP‐A (N = 46) were followed up across 36 months following treatment. A MIXED ANCOVA was applied to compare the effectiveness of these interventions in reducing severity of borderline symptoms (the primary outcome), impulsivity, self‐harm, emotion dysregulation and anger (secondary outcomes). The trial was retrospectively registered at IRCT20231106059970N1.ResultsBoth primary outcomes and secondary outcomes decreased significantly following both MBT‐A and UP‐A. In comparison with MBT‐A, UP‐A was more effective in reducing emotional dysregulation, but levels of remission declined progressively up to 36 months of follow‐up following both treatments.ConclusionsUP‐A appears to be more effective than MBT‐A in reducing emotional dysregulation in adolescents with BPD, despite being a shorter and less intensive treatment. An important caveat is that the treatment induced changes were largely limited to the emotion dysregulation aspect of BPD; other aspects (interpersonal and identity disturbances) were largely unchanged by either treatment.
Single‐Phase Single‐Stage Integrated Ćuk Inverter Operating in Discontinuous Conduction Mode for Autonomous Operation
Authors: Inoue Rafael Takeshi , Dionizio Anderson Aparecido , Sampaio Leonardo Poltronieri , da Silva Sérgio Augusto Oliveira , de Brito Moacyr Aureliano Gomes 
Published: February 2025

ABSTRACTDC microgrids are required to supply energy to AC local loads in many applications. To address this need, integrated inverters have been rising as an excellent solution for interfacing AC loads with the microgrid due to their good conversion efficiency, lower costs, and enhanced reliability. Thus, this paper explores and analyzes the single‐phase single‐stage integrated Ćuk inverter (ICI). The ICI is designed to operate in discontinuous conduction mode with an improved switching strategy. The inverter's output voltage is regulated by a single‐loop control system employing a proportional integral multiresonant controller. This paper presents a comprehensive qualitative and quantitative mathematical analysis of the ICI, such as the main system equations, component sizing, and the converter modeling using the state‐space technique associated with the small‐signal analysis. The ICI distinguishes itself by (i) reduced number of electrical/electrical components; (ii) operation with a single high‐frequency switch, while the remaining bridge switches operate at low frequency; and (iii) ability to step up the input voltage while supplying an AC voltage in its output. The feasibility and functionality of the ICI are demonstrated from computational simulation and experimental results. The ICI provides an AC output voltage with low harmonic distortion and presents an efficiency greater than 96%.
Analysis and Design of Constant Current/Constant Voltage Output of Array Multitransmitter Inductive Power Transfer System
Authors: Li Da , Sun Pan , Lu Jianghua , Rong Enguo , Li Yuan , Wu Xusheng , Deng Qijun 
Published: February 2025

ABSTRACTWireless power transfer has been widely used in unmanned aerial vehicle (UAV) charging due to its convenient and flexible noncontact charging characteristics. The working area of the uncoupler inductive power transfer (IPT) system is limited, and ZVS is easily lost in phase‐shift modulation. This paper proposes a method for constant current (CC) /constant voltage (CV) output in an array multitransmitter IPT system based on HFP modulation in a wide working area. The HFP modulation method easily realizes the current phase synchronization of multiple transmitter coils, and the size can be adjusted. At the same time, an efficient optimization model for a multitransmitter IPT system based on HFP modulation is proposed. Finally, an experimental platform for the array multitransmitter IPT system is built to verify the effectiveness of the CC/CV output realization method and the efficiency optimization model for the multitransmitter IPT system. The maximum errors in charging current and voltage are less than 2.52% and 2.1%, respectively, and the peak efficiency of the IPT system reaches 87.3%.
Clinical Outcomes Among Adolescents Diagnosed With Anorexia Nervosa During the COVID‐19 Pandemic
Authors: Coret Alon , Burstein Brett , Agostino Holly 
Published: February 2025

ABSTRACTObjectiveThe COVID‐19 pandemic was associated with a significant rise in the incidence of anorexia nervosa (AN) and atypical anorexia nervosa (AAN), longer wait times and reduced opportunities for in‐person medical services. How these changes affected clinical outcomes among adolescents newly diagnosed with AN/AAN remains largely unknown.MethodsWe performed a retrospective analysis of standardized intake and follow‐up data from a pediatric eating disorder program to compare clinical outcomes among adolescents newly diagnosed with AN/AAN during pre‐pandemic (July/2017–December/2018) and pandemic (July/2020–December/2021) periods. Clinical data were collected at the time of diagnosis and at 1‐, 3‐, 6‐, and 12‐month intervals. The primary outcomes were unscheduled AN/AAN‐related emergency department visits and need for medical hospitalization.ResultsOverall, 253 patients were included (pre‐pandemic = 77; pandemic = 176). By 12‐months following diagnosis, 18.8% (95% CI 13.3%–25.3%) of patients diagnosed during the pandemic had unscheduled AN/AAN‐related emergency department visits, compared to 7.8% (95% CI 2.9%–16.2%, p = 0.03) of those diagnosed pre‐pandemic. Medical hospitalization was required more frequently in the pandemic group (35.8%; 95% CI 28.7%–43.4%) compared to pre‐pandemic (15.6%; 95% CI 8.3%–25.6%, p = 0.001). Mean weight gain at 12‐months did not differ between groups (8.1 kg pre‐pandemic vs. 8.8 kg pandemic; p = 0.35) however the mean time to target weight was longer in the pandemic group (2.7 vs. 4.4 months; p = 0.002).ConclusionPatients newly diagnosed with AN/AAN during the pandemic had significantly more AN/AAN‐related emergency department visits and hospitalizations and took longer to achieve target weight than those diagnosed pre‐pandemic. These findings suggest a more complicated treatment course among adolescents diagnosed with AN/AAN during the pandemic.
Growth differentiation factor‐15 and N‐terminal pro‐BNP in acute heart failure with preserved ejection fraction
Authors: Otaki Yoichiro , Watanabe Tetsu , Shimizu Mari , Tachibana Shingo , Sato Junya , Kobayashi Yuta , Tamura Harutoshi , Kato Shigehiko , Nishiyama Satoshi , Takahashi Hiroki , Arimoto Takanori , Watanabe Masafumi 
Published: February 2025

AbstractAimsHeart failure with preserved ejection fraction (HFpEF) continues to be an increasingly common health problem associated with a high mortality rate. Elevated levels of Growth differentiation factor‐15 (GDF15) and N‐terminal pro‐brain natriuretic peptide (NT‐proBNP) are reportedly associated with poor clinical outcomes in a broad range of cardiovascular diseases. The aim of the present study was to examine the effect of the combined assessment of these markers on clinical outcomes in patients with HFpEF.MethodsThis study is the prospective observational study. We measured the serum levels of GDF15 and NT‐proBNP in 643 patients (mean age 73 ± 12, 42% females). All patients were prospectively followed up for a median period of 1998 days. Total 132 HF‐related events and 88 all‐cause deaths occurred during the follow‐up period.ResultsMultivariate Cox proportional hazards regression analysis demonstrated that both serum GDF15 and NT‐proBNP levels were independently associated with HF‐related events after adjustment for confounding risk factors (GDF15: hazard ratio, 1.72; 95% confidence interval, 1.35–2.19; P < 0.0001 and NT‐proBNP: hazard ratio, 1.63; 95% confidence interval, 1.25–2.13; P = 0.0003). Serum GDF15 levels improved the prediction capacity for HF‐related events (0.7405 vs. 0.7190; P = 0.0422), with a significant net reclassification index (0.2724) and integrated discrimination improvement (0.0246). The C indices of GDF15 for HF‐related events and all‐cause deaths were significantly larger than those of NT‐proBNP in men (HF‐related events: 0.7389 vs. 0.6721; P = 0.0393, and all‐cause deaths: 0.6922 vs.0.6109; P = 0.0262) but not in women. The combination of GDF15 and NT‐proBNP levels stratified patients with HFpEF, identifying those at a high risk for HF‐related events and all‐cause deaths.ConclusionsSerum GDF15 could be an additional prognostic information to NT‐proBNP in patients with HFpEF. The prognostic abilities of serum GDF15 and NT‐proBNP differed according to sex. These markers were the feasible markers for patients with HFpEF, identifying those at a high risk for HF‐related events and all‐cause deaths.
Searching for New Four‐membered Palladacycles Derived from Anilines: Influence of the N‐Substituents in the Reaction Outcome
Authors: Chicote María‐Teresa , Bautista Delia , Vicente José , Saura‐Llamas Isabel 
Published: February 2025

AbstractThe reactions of iodoanilines IC6H4NRR′‐2 with [Pd(PPh3)4] gave complexes [Pd(C6H4NRR′‐2}I(PPh3)2] [R=H, R’=H (1 a), Me (1 b); R=R’=Me (1 c)] while a mixture of 1 a, and the dimeric [Pd{μ‐C,N‐C6H4NH2‐2)I(PPh3)]2 (2 a) was obtained when the appropriate iodoaniline was reacted with [Pd(dba)2] (dba=dibenzylideneacetone) and 1 equiv. of PPh3. The phosphonium salts [Ph3PC6H4NRMe‐2]OTf [R=H (3 b), Me (3 c)] formed upon reacting complexes 1 b,c with TlOTf (OTf=CF3SO3). Complexes of the type [Pd(C6H4NRR′‐2}I(N N)] (4) were obtained from the reaction of [Pd(dba)2] with the appropriate iodoaniline and a N N bidentate ligand (N N=4,4′‐di‐tert‐butyl‐2,2′‐bipyridine or N,N,N′,N′‐tetramethylethylenediamine). Complexes 4 reacted with TlOTf and PPh3 or XyNC (Xy=C4H4Me2‐2,6) to give [Pd(C6H4NRR′‐2)(N N)(PPh3)]OTf (5) or [Pd{C,N‐C(=NHXy)C6H4NRR′‐2)(N N)]OTf (6), respectively. In the absence of any added ligand, the reactions of complexes 4 with TlOTf produced the dimeric complexes [Pd{μ‐C,N‐C6H4NHR‐2)(N N)]2(OTf)2 (7) or the four‐membered palladacycles [Pd(κ2‐C6H4NMe2‐2)(N N)]OTf (8), depending on the substitution degree of the aniline reagent.