bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation on the accuracy of field widths and the quantitative relationship with energy variations for dynamic jaws helical tomotherapy
Authors: Poon Ho Ming , Chiu Tin Lok , Yu Siu Ki 
Published: December 2023

AbstractBackground and purposeTomoEDGE is an advanced technology for TomoTherapy treatment delivery by introducing a sliding‐window dynamic jaw motion. The front and back jaws move independently at the start and end of a target volume along the longitudinal couch direction to reduce the undesired dose to the normal tissues. The accuracy of field width is essential to treatment delivery in this regard. The purpose of this work was to analyze the performance of dynamic jaws on helical tomotherapy and investigate the relationship with energy variation.MethodsThe Tomotherapy‐Quality‐Assurance (TQA) Dynamic Field Width procedure was performed monthly across three tomotherapy machines. All field widths were analyzed, especially the FWHM of the 10 mm field width. Field width measurements were compared with the ratio of Percentage Depth Dose at 20 and 10 cm to render the value of correlation. Changes in beam FWHM and energy were further discussed. Two‐year data were collected for this purpose.ResultsOn average, measured field widths in each unit agreed within 1% tolerance recommendation stated. The average absolute difference between reference and measured FWs in each unit was approximately 0.07 mm. An increase of 1.5% in the FW of the 10 mm nominal beam width was correlated with a 1% increase in PDD20,10 ratio, implying a positive correlation between the two factors (p < 0.002).ConclusionsA positive correlation between nominal 10 mm FW and PDD20,10 was observed. In the case that the PDD20,10 marginally passes the QA tests, users are recommended to consider further verification on Dynamic Jaws to ensure the smallest field width to be within tolerance, which is essential to maintain effective treatment in TomoEDGE system. Since the regression of this study was a single‐factor model, other confounding factors such as the focal spot size of linear accelerator should also be considered when evaluating the machine status.
PenTag, a Versatile Platform for Synthesizing Protein‐Polymer Biohybrid Materials
Authors: Mohsenin Hasti , Pacheco Jennifer , Kemmer Svenja , Wagner Hanna J. , Höfflin Nico , Bergmann Toquinha , Baumann Tim , Jerez‐Longres Carolina , Ripp Alexander , Jork Nikolaus , Jessen Henning J. , Fussenegger Martin , Köhn Maja , Timmer Jens , Weber Wilfried 
Published: December 2023

AbstractThe site‐specific and covalent conjugation of proteins on solid supports and in hydrogels is the basis for the synthesis of biohybrid materials offering broad applications. Current methods for conjugating proteins to desired targets are often challenging due to unspecific binding, unstable (noncovalent) coupling, or expensive and difficult‐to‐synthesize ligand molecules. Here, is presented PenTag, an approach for the bioorthogonal, highly specific, and covalent conjugation of a protein to its ligand for various applications in materials sciences. Penicillin‐binding protein 3 (PBP3) is engineered and shows that this protein can be used for the stable and spontaneous conjugation of proteins to dyes, polymers, or solid supports. PenTag as a crosslinking tool is applied for synthesizing stimuli‐responsive hydrogels or for the development of a biohybrid material system performing computational operations emulating a 4:2 encoder. Based on this broad applicability and the use of a small, cheap, and easy‐to‐functionalize ligand and a stable, soluble recombinant protein, is seen PenTag as a versatile approach toward biohybrid material synthesis.
Metabolically Glycoengineered Neural Stem Cells Boost Neural Repair After Cardiac Arrest
Authors: Du Jian , Liu Xiao , Marasini Subash , Wang Zhuoran , Dammen‐Brower Kris , Yarema Kevin J. , Jia Xiaofeng 
Published: December 2023

AbstractCardiac arrest (CA)‐induced cerebral ischemia remains challenging with high mortality and disability. Neural stem cell (NSC) engrafting is an emerging therapeutic strategy with considerable promise that, unfortunately, is severely compromised by limited cell functionality after in vivo transplantation. This groundbreaking report demonstrates that metabolic glycoengineering (MGE) using the “Ac5ManNTProp (TProp)” monosaccharide analog stimulates the Wnt/β‐catenin pathway, improves cell adhesion, and enhances neuronal differentiation in human NSCs in vitro thereby substantially increasing the therapeutic potential of these cells. For the first time, MGE significantly enhances NSC efficacy for treating ischemic brain injury after asphyxia CA in rats. In particular, neurological deficit scores and neurobehavioral tests experience greater improvements when the therapeutic cells are pretreated with TProp than with “stand‐alone” NSC therapy. Notably, the TProp‐NSC group exhibits significantly stronger neuroprotective functions including enhanced differentiation, synaptic plasticity, and reduced microglia recruitment; furthermore, Wnt pathway agonists and inhibitors demonstrate a pivotal role for Wnt signaling in the process. These findings help establish MGE as a promising avenue for addressing current limitations associated with NSC transplantation via beneficially influencing neural regeneration and synaptic plasticity, thereby offering enhanced therapeutic options to boost brain recovery following global ischemia.
Integrated High Voltage, Large Capacity, and Long‐Time Cyclic Stability of Lithium Organic Battery Based on a Bipolar‐Type Cathode of Triphenylamine‐Hydrazone COF Material
Authors: Li Weijun , Huang Qidi , Shi Hongliang , Gong Wei , Zeng Liang , Wang Haiyang , Kuai Yu , Chen Zhangxin , Fu Haichang , Dong Yujie , Zhang Cheng 
Published: December 2023

AbstractCovalent organic frameworks (COFs) are a promising class of electrode materials for lithium‐ion batteries. However, the reported cathodes of COFs typically exhibit low potential and voltage plateaus, which limits their further applications. In this work, a new hydrazone three‐dimensional (3D) COF material with bipolar characteristics, PTB‐DHZ‐COF, is constructed by Schiff base condensation of monomeric PTB with DHZ. The cell with PTB‐DHZ‐COF as the cathode exhibits a wide potential range of 1.2–4.2 V and a discharge voltage plateau of over 3.6 V. PTB‐DHZ‐COFX composites are successfully prepared by compounding PTB‐DHZ‐COF with carbon nanotubes. PTB‐DHZ‐COF40 cells show high specific capacity (114.24 mAh·g−1 at 1000 mA·g−1), excellent cycling capability (86.3% capacity retention after 5000 cycles), and ultra‐high energy density (489 Wh·kg−1 at 50 mA·g−1). This work provides a new strategy for the design of new COF materials and the development of high‐performance organic energy storage electrodes.
All 3D‐Printed Soft High‐Density Surface Electromyography Electrode Arrays for Accurate Muscle Activation Mapping and Decomposition
Authors: Zhao Yi , Chen Chen , Lu Baoyang , Zhu Xiangyang , Gu Guoying 
Published: December 2023

AbstractHigh‐density surface electromyography (sEMG) electrode arrays enable the recording of tens to hundreds of channels of electromyographic signals, which have found wide applications in clinics and human‐machine interfaces. However, current manufacturing technologies of high‐density sEMG electrode arrays generally involve high‐cost equipments, complicated procedures, and insufficient programmability, severely hampering the rational design and practical applications of customized yet cost‐effective high‐density electrode arrays. Herein, the facile and efficient fabrication of novel 32‐channel soft high‐density sEMG electrode arrays by an all‐printed technique based on multimaterial direct ink writing 3D printing is presented. By employing rational four‐layer stacked structure designs with systematic ink printability evaluation, it can successfully realize seamless interfacial integration during the multimaterial printing, achieving reproducible, programmable, continuous fabrication of soft high‐density sEMG electrode arrays. The all 3D‐printed soft electrode arrays exhibit excellent stability, low impedance, and high signal‐to‐noise ratio superior to commercial products with an increase of 32.2%. Such intriguing properties enable this all 3D‐printed electrode arrays the unique capability of mapping muscle activation of the forearm, and the motor unit action potential trains can be precisely identified for varying hand gestures to effectively explore the innovative human‐machine interface toward diverse applications such as teleoperation and prosthetic control.
Achieving 21.4% Efficient CdSeTe/CdTe Solar Cells Using Highly Resistive Intrinsic ZnO Buffer Layers
Authors: Kujovic Luksa , Liu Xiaolei , Abbas Ali , Jones Luke O. , Law Adam M. , Togay Mustafa , Curson Kieran M. , Barth Kurt L. , Bowers Jake W. , Walls John M. , Oklobia Ochai , Lamb Dan A. , Irvine Stuart J. C. , Zhang Wei , Lee Chungho , Nagle Timothy , Lu Dingyuan , Xiong Gang 
Published: December 2023

AbstractIn this study, the use of intrinsic and highly insulating ZnO buffer layers to achieve high conversion efficiencies in CdSeTe/CdTe solar cells is reported. The buffer layers are deposited on commercial SnO2:F coated soda‐lime glass substrates and then fabricated into arsenic‐doped CdSeTe/CdTe devices using an absorber and back contact deposited by First Solar. The ZnO thickness is varied from 30 to 200 nm. The devices incorporating a 50 nm ZnO buffer layer achieved an efficiency of 21.23% without an anti‐reflection coating. An improved efficiency of 21.44% is obtained on a substrate with a multilayer anti‐reflection coating deposited prior to device fabrication. The highly efficient ZnO based devices are stable and do not develop anomalousJ‐Vbehavior following environmental tests. High resolution microstructural analysis reveals the formation of a high‐quality ZnO/CdSeTe interface. Unusually, chlorine is not detected as a discrete layer at the interface, these observations point to a high‐quality interface. The extrapolation ofVocto 0 K indicates that interface recombination dominates, suggesting that further improvement is possible. Using device modeling, an attempt is made to understand how this type of device performs so well.
Surface Functional Modification for Boosting Power Density of Hydrovoltaic Devices
Authors: Liu Yanhui , Li Zihao , Wang, Liying , Yang Xijia , Yang Yue , Li Xuesong , Jiang Yi , Gao Yang , Lü Wei 
Published: December 2023

AbstractGenerating electricity based on the interaction between water and materials is a new green energy harvesting technology. However, the performance based on streaming potential generation is not sufficient to drive microelectronic devices with high power supply demands. In this work, an asymmetric sandwich structure is designed with adjustable performance of hydrovoltaic devices as a power system for micro‐electronic devices. The flexible hydrovoltaic device structure that only consumes renewable energy is low‐cost, non‐polluting, and highly sustainable, achieving a satisfied output power density exceeding 124.5 µW·cm−2 (2075 µW·cm−3). Both experimental results and theoretical calculations reveal that the working principle of the device depends on the evaporation potential rather than the streaming potential. In addition, the integration of multiple devices makes it easy to drive electronic devices for correct operation and energy storage. For the first time, this integrated hydroelectric photovoltaic device has demonstrated the ability to charge commercial button‐type lithium batteries with great success. The current work combines asymmetric structure and tunable performance, providing an alternative method for high‐efficiency hydrovoltaic devices with high power density.
β‐Ketoenamine and Benzoxazole‐Linked Covalent Organic Frameworks Tailored with Phosphorylation for Efficient Uranium Removal from Contaminated Water Systems
Authors: Mei Douchao , Yan Bing 
Published: December 2023

AbstractThe complexity of nuclear wastewater treatment motivates the design and synthesis of highly selective and stable uranium adsorbents to provide environmental remediation. Herein, a post‐synthetic modification method is adopted to synthesize two β‐ketoenamine and benzoxazole‐linked COFs decorated with abundant phosphonic groups for the uranium removal, which overcome the disadvantage of amidoxime groups with stronger affinity for vanadium than uranium. The U‐uptake capacity of β‐ketoenamine‐based TpPa‐2OH‐PHos reaches 410.9 mg g−1 (pH 5, C0 = 100 mg L−1 and m/V = 1/10 g L−1). Notably, U‐uptake capacity of TpDBD‐PHos reaches 633.3 mg g−1 at the same conditions. More abundant phosphonic groups and the synergistic effect between the benzoxazole rings and phosphonic groups may be responsible for the good uranium adsorption performance for TpDBD‐PHos. Moreover, TpDBD‐PHos exhibits a satisfactory uranium removal rate of 87.71% in actual rainwater samples. The X‐ray pHotoelectron spectroscopy (XPS) analysis suggests that the strong interaction between U(VI) and oxygen/nitrogen atoms in the frameworks plays a vital role for the adsorption of TpPa‐2OH‐PHos and TpDBD‐PHos, which agrees well with the results of density functional theory (DFT) calculations. The good chemostability and excellent selectivity demonstrate that TpDBD‐PHos is an outstanding candidate for the removal of uranium from contaminated water systems.
Structure‐Based Machine Learning Enables Discovery of Mn4+‐Activated Red‐Light Fluorides for Ultrawide‐Gamut Mini‐Light‐Emitting Diodes
Authors: Wang Yuanjing , Tang Wenyu , Zhang Chuang , Molokeev Maxim S. , Ming Hong , Zhou Yayun , Peng Shuai , Song Enhai , Zhang Qinyuan 
Published: December 2023

AbstractMn4+‐activated fluorides with a saturated red color and sharp line emission are ideal for applications in the light‐emitting diodes (LEDs) backlight for displays. However, the emissions attributed to 2E→4A2 parity and spin‐forbidden transitions limit the design and adjustments of emission wavelength and chromaticity coordinates. Herein, machine learning algorithms are used to build a wavelength‐prediction model for Mn4+‐activated fluorides. The model precisely identifies the key structural features that affect wavelengths and discovers target materials. The predicted candidate Cs2NaAlF6:Mn4+ (CNAF) with a long‐wavelength zero‐phonon‐line emission at 628 nm exhibits a redshift in comparison with other reported Mn4+‐activated fluorides and commercial K2SiF6:Mn4+, but maintains narrow spectral emission with full‐width half maximum (FWHM) of 11.2 nm. The redshift and narrow spectra result in a color purity of 99.7% and Commission Internationale de L'Eclairage (CIE) chromaticity coordinate of (0.7032,0.2967) that is close to the pure red‐light point of Recommendation BT. 2020 (Rec. 2020). Moreover, CNAF is prepared as a transparent red‐light film, and the device fabricated using the blue‐light mini‐LEDs, green quantum‐dot film, and CNAF film exhibits a wide color‐gamut of 121.5% National Television Standards Committee (NTSC) or 90.6% Rec. 2020, suggesting that CNAF has potential for wide‐color‐gamut displays.
Achieving Complete Tumor Clearance: A Minimalist Manganese Hydrogel for Magnetic Resonance Imaging‐Guided Synergetic Microwave Ablation and Chemodynamic Therapy
Authors: Zhou Yan , Shu Gang , Luo Ying , Wang Fengmei , Jing Xiang , Pan Jinbin , Sun Shao‐Kai 
Published: December 2023

AbstractThe combination of microwave ablation (MWA) and chemodynamic therapy (CDT) presents a promising strategy for complete eradication of residual tumor after MWA. However, it remains challenging and urgent to develop a facile, biocompatible, and imaging‐guided platform for the achievement of this goal. Herein, a minimalist manganese hydrogel (ALG‐Mn hydrogel) is proposed for synergistic MWA and CDT to completely eradicate tumor in vivo. The ALG‐Mn hydrogel is prepared using a simple mixing method and exhibits excellent syringeability, remarkable microwave sensitivity, and potent Fenton‐like activity. By assisting in MWA procedures, the ALG‐Mn hydrogel enables both elimination of primary tumor mass through enhanced MWA efficacy and eradication of potential residual tumor tissues via robust CDT. This approach achieves complete tumor clearance without additional drug loading. Furthermore, the paramagnetic Mn2+ component allows real‐time dynamic visualization of the ALG‐Mn hydrogel at the tumor site via magnetic resonance imaging. To the best of knowledge, the proposed ALG‐Mn hydrogel represents the minimalist biocompatible platform for imaging‐guided synergistic MWA and CDT toward achieving complete tumor clearance.
Sr‐Stabilized IrMnO2 Solid Solution Nano‐Electrocatalysts with Superior Activity and Excellent Durability for Oxygen Evolution Reaction in Acid Media
Authors: Kuang Jianren , Deng Binglu , Jiang Zhongqing , Wang Yongjie , Jiang Zhong‐Jie 
Published: December 2023

AbstractThe development of cost‐effective catalysts for oxygen evolution reaction (OER) in acidic media is of paramount importance. This work reports that Sr‐doped solid solution structural ultrafine IrMnO2 nanoparticles (NPs) (≈1.56 nm) on the carbon nanotubes (Sr‐IrMnO2/CNTs) are efficient catalysts for the acidic OER. Even with the Ir use dosage 3.5 times lower than that of the commercial IrO2, the Sr‐IrMnO2/CNTs only need an overpotential of 236.0 mV to drive 10.0 mA cm−2 and show outstanding stability for >400.0 h. Its Ir mass activity is 39.6 times higher than that of the IrO2 at 1.53 V. The solid solution and Sr‐doping structure of Sr‐IrMnO2 are the main origin of the high catalytic activity and excellent stability of the Sr‐IrMnO2/CNTs. The density function theory calculations indicate that the solid solution structure can promote strong electronic coupling between Ir and Mn, lowering the energy barrier of the OER rate‐determining step. The Sr‐doping can enhance the stability of Ir against the chemical corrosion and demetallation. Water electrolyzers and proton exchange membrane water electrolyzers assembled with the Sr‐IrMnO2/CNTs show superb performance and excellent durability in the acid media.
Tetrazine‐Linked Covalent Organic Frameworks With Acid Sensing and Photocatalytic Activity
Authors: Zadehnazari Amin , Khosropour Ahmadreza , Altaf Ataf Ali , Rosen Andrew S. , Abbaspourrad Alireza 
Published: December 2023

AbstractThe first synthesis and comprehensive characterization of two vinyl tetrazine‐linked covalent organic frameworks (COF), TA‐COF‐1 and TA‐COF‐2, are reported. These materials exhibit high crystallinity and high specific surface areas of 1323 and 1114 m2 g−1. The COFs demonstrate favorable band positions and narrow band gaps suitable for light‐driven applications. These advantages enable TA‐COFs to act as reusable metal‐free photocatalysts in the arylboronic acids oxidation and light‐induced coupling of benzylamines. In addition, these TA‐COFs show acid sensing capabilities, exhibiting visible and reversible color changes upon exposure to HCl solution, HCl vapor, and NH3 vapor. Further, the TA‐COFs outperform a wide range of previously reported COF photocathodes. The tetrazine linker in the COF skeleton represents a significant advancement in the field of COF synthesis, enhancing the separation efficiency of charge carriers during the photoreaction and contributing to their photocathodic properties. TA‐COFs can also degrade 5‐nitro‐1,2,4‐triazol‐3‐one (NTO), an insensitive explosive present in industrial wastewater, in 20 min in a sunlight‐driven photocatalytic process; thus, revealing dual functionality of the protonated TA‐COFs as both photodegradation and Brønsted acid catalysts. This pioneering work opens new avenues for harnessing the potential of the tetrazine linker in COF‐based materials, facilitating advances in catalysis, sensing, and other related fields.
Leveraging the Snap Buckling of Bistable Magnetic Shells to Design a Refreshable Braille Dot
Authors: Abbasi Arefeh , Chen Tian , Aymon Bastien F.G. , Reis Pedro M. 
Published: December 2023

AbstractA design concept is proposed for the building block, adot, of programmable braille readers utilizing bistable shell buckling, magnetic actuation, and pneumatic loading. The design process is guided by Finite Element simulations, which are initially validated through precision experiments conducted on a scaled‐up, single‐shell model system. Then, the simulations are leveraged to systematically explore the design space, adhering to the standardized geometric and physical specifications of braille systems. The findings demonstrate the feasibility of selecting design parameters that satisfy both geometric requirements and blocking forces under moderate magnetic fields, facilitated by pneumatic loading to switch between the two stable states. While the study is focused on experimentally validated numerical simulations, it is also identify several manufacturing challenges that need to be resolved for future physical implementations .
Biocompatible 3D Printed MXene Microlattices for Tissue‐Integrated Antibiotic Sensing
Authors: Tiwari Anand P. , Panicker Sreejith S. , Huddy Julia E. , Rahman Md Saifur , Hixon Katherine R. , Scheideler William J. 
Published: December 2023

Abstract3D continuous mesoscale architectures of nanomaterials possess the potential to revolutionize real‐time electrochemical biosensing through higher active site density and improved accessibility for cell proliferation. Herein, 3D microporous Ti3C2TX MXene biosensors are fabricated to monitor antibiotic release in tissue engineering scaffolds. The Ti3C2TX‐coated 3D electrodes are prepared by conformal MXene deposition on 3D‐printed polymer microlattices. The Ti3C2TX MXene coating facilitates direct electron transfer, leading to the efficient detection of common antibiotics such as gentamicin and vancomycin. The 3D microporous architecture exposes greater electrochemically active MXene surface area, resulting in remarkable sensitivity for detecting gentamicin (10–1 mM) and vancomycin (100–1 mM), 1000 times more sensitive than control electrodes composed of 2D planar films of Ti3C2TX MXene. To characterize the suitability of 3D microporous Ti3C2TX MXene sensors for monitoring drug elution in bone tissue regeneration applications, osteoblast‐like (MG‐63) cells are seeded on the 3D MXene microlattices for 3, 5, and 7 days. Cell proliferation on the 3D microporous MXene is tracked over 7 days, demonstrating its promising biocompatibility and its clinical translation potential. Thus, 3D microporous Ti3C2TX MXene can provide a platform for mediator‐free biosensing, enabling new applications for in vivo monitoring of drug elution.
Tunable Multifunctional Metamaterial Sandwich Panel with Quasi‐Zero Stiffness Lattice Cores: Load‐Bearing, Energy Absorption, and Vibration Isolation
Authors: Liu Wenlong , Wu Lingling , Sun Jingbo , Zhou Ji 
Published: December 2023

AbstractThe interest in novel mechanical metamaterials that offer advanced functionalities and mechanical tunability for highly compatible multifunctional performance in state‐of‐the‐art engineering applications is growing. Here, a novel tunable multifunctional mechanical metamaterial, also known as a metamaterial sandwich panel, which can achieve load‐bearing, energy absorption, and low‐frequency vibration isolation properties simultaneously, is reported. The designed metamaterial sandwich panel is composed of a quasi‐zero stiffness (QZS) lattice core and two kirigami‐style surfaces, which endow the metamaterial sandwich panel with multi‐function performance and tunable properties. As a proof‐of‐concept, the mechanical properties and tunable multifunctional performance of the proposed metamaterial sandwich panel are demonstrated both in simulations and experiments. This work provides a new alternative for designing novel mechanical metamaterials with tunable multifunctional performance and may have potential applications in a variety of engineering applications, such as medical transportation, marine systems, and aerospace applications.