bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERAN SUTRADARA DALAM PEMBUATAN KARYA FEATURE PERJALANAN BERJUDUL “PESONA ADAT DAN TRADISI DESA SADE”
Authors: Nabila Herdefa , Irawan Rahmat Edi 
Published: October 2023

Desa Sade merupakan salah satu desa yang berada di Kapupaten Lombok Tengah. Desa ini memiliki memegang teguh adat dan tradisinya secara turun temurun hingga saat ini sebagai daya tarik wisata budaya. Desa sade memiliki suku yang sangat dikenal dikalangan wisatawan, yaitu Suku Sasak. Kearifan lokal di Desa Sade yang memiliki daya tarik yaitu tarian Gendang Beleq, bangunan khas Suku Sasak, tarian Gendang Beleq, tenun, dan Peresean. Maka dari itu pencipta membuat sebuah feature perjalanan “Pesona Adat dan Tradisi Desa Sade”. Dalam penciptaan ini penulis sebagai Sutradara yang sangat bertanggung jawab terhadap produksi ini dari awal pembuatan ide konsep yaitu Pra Produksi, Produksi hingga Pasca Produksi. Dengan adanya feature perjalanan ini bertujuan untuk mengedukasi, menghibur, serta menjadi opsi destinasi bagi para wisatawan, bahwa aktivitas wisata di Lombok tidak hanya berupa pantai atau bukit saja namun ada juga wisata budaya. Alasan pencipta membuat program feature perjalanan, karena feature perjalanan menyajikan tayangan berupa artikel kreatif tentang suatu kejadian, keadaan atau aspek kehidupan secara fakta dan penonton dapat merasakan visual audio dengan nyata. Dengan harapan pencipta, program ini dapat memberikan hiburan, informasi dan edukasi serta memberikan hiburan alternatif bagi para wisatawan yang ingin berkunjung ke Lombok.
RANCANGAN PROGRAM LAYANAN BIMBINGAN DAN KONSELING UNTUK MENGATASI PROBLEMATIKA EKSTERNAL MAHASISWA FAKULTAS ILMU SOSIAL DAN HUMANIORA 2020
Authors: Hamidah Wardatul 
Published: October 2023

Penelitian ini dilator belakangi karena adanya suatu problematika yang dihadapi oleh mahasiswa selama masa perkuliahannya. Penelitian ini bertujuan untuk mengetahui: 1) Profil problematika eksternal dari mahasiswa Fakultas Ilmu Sosial dan Humaniora angkatan 2020. 2) Merancang program layanan Bimbingan dan Konseling untuk mengatasi problematika eksternal mahasiswa Fakultas Ilmu Sosial dan Humaniora angkatan 2020.Penelitian ini menggunakan jenis penelitian Research and Development (R&D). Populasi dari penelitian ini merupakan mahasiswa Fakultas Ilmu Sosial dan Humaniora angkatan 2020 dengan jumlah sebanyak 472 orang mahasiswa. Jumlah sampel pada penelitian ini sebanyak 82 orang mahasiswa. Teknik pengambilan sampel dalam penelitian ini menggunakan simple random sampling, dan instrument yang digunakan adalah angket.Berdasarkan hasil penelitian ini, mengungkapkan bahwa : 1) Profil problematika eksternal mahasiswa Fakultas ilmu Sosial dan Humaniora angkatan 2020 berada pada kategori tinggi. 2) Rancangan program yang telah divalidasi, berada pada kategori ”Diterima”. Berdasarkan hasil penelitian ini direkomendasikan kepada konselor Labor BK Universitas PGRI Sumatera Barat agar dapat menerapkan rancangan program layanan bimbingan dan konseling untuk mengatasi problematika eksternal mahasiswa Fakultas Ilmu Sosial dan Humaniora angkatan 2020 Universitas PGRI Sumatera Barat.
DAMPAK NEGATIF SOCIAL CLIMBER DI MEDIA SOSIAL PADA REMAJA
Authors: Waqiati Hasna Amania 
Published: October 2023

Remaja ingin mendapatkan pengakuan sosial dari teman sebayanya. Sehingga mereka berupaya agar media sosial mereka mampu mengikuti trend yang sedang muncul di kelompoknya. Namun, hal tersebut tidak selamanya sesuai dengan kondisi mereka yang sebenarnya. Sehingga mereka berperilaku social climber agar bisa diterima oleh kalangannya. Sayangnya, perilaku demikian membawa dampak negatif bagi para remaja. Tujuan dari penelitian ini untuk mengetahui bagaimana dampak negatif social climber di media sosial bagi remaja. Penelitian ini menggunakan metode penelitian studi kepustakaan yakni dengan mengumpulkan buku-buku, artikel dari internet, maupun artikel dari jurnal penelitian. Hasil dari penelitian ini menunjukan bahwa terdapat beberapa dampak negatif yang ditimbulkan karena perilaku social climber di media sosial pada remaja antara lain harga diri dan kepercayaan diri yang menurun, memunculkan kecemasan dan depresi, serta memunculkan perilaku flexing yang dapat berujung ke gaya hidup konsumtif.. Diharapkan melalui penelitian ini para remaja mampu memilih lingkungan pertemanan yg baik sehingga tidak memunculkan dampak negatif perilaku social climber. Selain itu diharapkan para orang tua memberikan lingkungan tempat tinggal maupun sekolah yang baik sehingga anak dapat memiliki teman yang membawa dampak positif bagi perkembangannya.
PENGARUH PERMAINAN PUZZLE TERHADAP KETERAMPILAN KOGNITIF ANAK PADA USIA 5-6 TAHUN DI RAUDHATUL ATHFAL
Authors: Aspini Aspini , Mujiburrahman Mujiburrahman , Muzanni Ahmad 
Published: October 2023

Tujuan dalam penelitian ini adalah ingin mengetahui pengaruh permainan puzzle terhadap keterampilan kognitif anak usia 5-6 tahun di RA Terampil Dasan Sari tahun pelajaran 2019/2020. Penelitian ini menggunakan metode eksperimen dan yang menjadi populasi adalah seluruh siswa kelompok B di RA Terampil Dasan Sari yang berjumlah 10 orang. Metode untuk mengumpulkan data yaitu observasi pre tes dan post test sebagai metode utama, sedangkan metode dokumentasi dan wawancara sebagai metode pelengkap. Untuk menganalisis data menggunakan rumus t-tes. Dari hasil uji t tes menunjukkan bahwa nilai hitung sebesar 24,17, t tabel dengan taraf signifikan 5% pada db 10, ternyata besarnya angka batas penolakan Hipotesis Nol (Ho) yang dinyatakan dalam tabel distribusi t adalah 1,833, kenyataan ini menunjukkan bahwa nilai t hitung lebih besar dari pada nilai t tabel (24,17 1,833). Hal ini berarti bahwa Hipotesis Nol (Ho) ditolak dan Hipotesis Alternatif (Ha) diterima, maka dapat ditarik kesimpulan bahwa: Ada pengaruh permainan puzzle terhadap keterampilan kognitif anak pada usia 5-6 tahun di RA Terampil Dasan Sari tahun pelajaran 2019/2020, artinya hasil penelitian ini adalah “signifikan”.
Students’ Perception Towards Teachers Strategies in Teaching Reading Skill
Authors: Zahro Fatimatuz , Wahab Abdul Aziz , Ferdiyanto Fery 
Published: October 2023

Students' perceptions towards teachers strategies in teaching reading skills are also important to know by teachers, so that they can be used as reflections to improving their strategies in teaching reading. This research different between some previous study because the focus in the some previous is more generally because analyze about students’ perception towards teachers attitude, teaching style and attitude in learning English. Meanwhile, in this research is more specifically because analyze about students’ perception towards teachers strategies and only focus in reading skill. In previous study use a quantitative method but in this study use a qualitative method. The aim of this study was to find out how students' perceptions towards teachers strategies in teaching reading skills.The participants in this study were eleventh grade students at SMAI MU Jatiurip. This study used interviews, observation and documentation to obtain data.The result showed that students’ perception towards teacher’s strategies in teaching reading at SMAI MU Jatiurip is give had positive percepatan with all of the teaching strategies in teaching reading. They are predicting, question and generating and answering, role plays and think pair share except summarizing strategy because they feel boring about learning reading material when the teacher used summarizing strategy. The most of students prefer to predicting strategy because students understand lessons more quickly when using predicting strategies.
An ovulatory menstrual health literacy program within a Health Promoting School framework: reflections from school staff
Authors: Roux Felicity , Hendriks Jacqueline , Burns Sharyn , Chih HuiJun 
Published: October 2023

IntroductionPoor ovulatory menstrual (OM) health experiences and low levels of OM health literacy compromise the future adult health and wellbeing of female adolescents.MethodsThis qualitative study sought reflections from secondary school staff on an intervention adopting the Health Promoting School (HPS) approach which aimed to enhance wellbeing through improving OM health literacy.ResultsTwenty female school staff from ten schools participated: three deans, 11 Health and Science teachers and six healthcare professionals. Five interviews and three focus groups were conducted, and 12 anonymously notated booklets of the program were returned. Reflective thematic analysis identified six themes: a need for OM health literacy; curricular challenges; teaching perspectives; school socio-emotional environment; community engagement; and resourcing needs.DiscussionAlignment with a HPS-framework may resolve some barriers to future program implementation, such as curricular restrictions, interprofessional co-ordination and community engagement. Additional barriers, relating to menstrual disdain, knowledge gaps and an absence of professional development, may be addressed with training to ensure that OM health education is framed positively and addresses student wellbeing.
Assessment of threat of concurrent SARS-CoV-2 and DENV infection in the COVID-19 pandemic in Brazil in 2020: diagnostic and immunological findings
Authors: Rodrigues Joyce Carnevale , Familiar-Macedo Débora , Medeiros Thalia , Carvalho Fabiana Rabe , Almeida Jorge Reis , Silva Andrea Alice , dos Santos Flávia Barreto , de Souza Luiz José , Damasco Paulo Vieira , Azeredo Elzinandes Leal , de-Oliveira-Pinto Luzia Maria 
Published: October 2023

IntroductionThe first peak of COVID-19 in Brazil was between April and May 2020, at a time of the year when outbreaks of other tropical diseases, such as dengue, would be expected. COVID-19 and dengue have similar pathogenesis. In general, both may lead to mild symptoms but may also cause severe and even fatal symptoms, especially in patients with comorbidities and probably in cases of overlapping infections. The general objective of this study was to assess whether, during the 2020 pandemic, there were cases of concomitant infection between SARS-CoV-2 and DENV.MethodsFor this, we evaluated the specificity and sensitivity of commercial serological anti-SARS-CoV-2 kits using plasma samples from patients with dengue and healthy donors recruited before COVID-19. In the case of confirmed cases of COVID-19/dengue, we evaluated the clinical evolution of these coinfected patients, compared with mono-infected patients; and quantified chemokines CCL2 and CXCL8 by ELISA in COVID-19 patients in order to correlate them with COVID-19/dengue severity and cases.Results and DiscussionOur results showed that commercial IgA and IgG anti-SARS-CoV-2 kits presented high sensitivity and specificity. This allowed us to see a low rate of co-detection or coinfection between SARS-CoV-2 and DENV in Rio de Janeiro. Among the 57 COVID-19 patients, anti-DENV IgM was detected in five (8.8%). COVID-19/dengue coinfected patients showed no clinical worsening of COVID-19 and cases in which COVID-19 patients had previous exposure to DENV did not influence the clinical severity of COVID-19. Lastly, CCL2 and CXCL8 appeared to be good markers of COVID-19 severity and did not show increased levels in COVID-19/dengue cases.
Systematic analysis of cuproptosis-related genes in immunological characterization and predictive drugs in Alzheimer’s disease
Authors: Nie Bin , Duan Yefen , Xie Xuelong , Qiu Lihua , Shi Shaorui , Fan Zhili , Zheng Xuxiang , Jiang Ling 
Published: October 2023

ObjectivesThis study aimed to make a systematic analysis of cuproptosis-related genes (CRGs) in immunological characterization and predictive drugs in Alzheimer’s disease (AD) through bioinformatics and biological experiments.MethodsThe molecular clusters related to CRGs and associated immune cell infiltrations in AD were investigated. The diagnostic models were constructed for AD and different AD subtypes. Moreover, drug prediction and molecular docking were also performed. Subsequently, a molecular dynamics (MD) simulation was conducted to further verify the findings. Finally, RT-qPCR validation was performed.ResultsThe characterization of 12 AD-related CRGs was evaluated in AD, and a diagnostic model for AD showed a satisfying discrimination power based on five CRGs by LASSO regression analysis. The dysregulated CRGs and activated immune responses partially differed between patients with AD and healthy subjects. Furthermore, two molecular subtypes (clusters A and B) with different immune infiltration characteristics in AD were identified. Similarly, a diagnostic model for different AD subtypes was built with nine CRGs, which achieved a good performance. Molecular docking revealed the optimum conformation of CHEMBL261454 and its target gene CSNK1D, which was further validated by MD simulation. The RT-qPCR results were consistent with those of the comprehensive analysis.ConclusionThis study systematically elucidated the complex relationship between cuproptosis and AD, providing novel molecular targets for treatment and diagnosis biomarkers of AD.
The treatment of persistent spinal pain syndrome with epidural pulsed radiofrequency: improvement of the technique
Authors: Dario Alessandro , Capelli Sergio 
Published: October 2023

BackgroundIn Persistent Spinal Pain Syndrome (PSPS), Pulsed Radiofrequency (PRF) is a used procedure. The results of PRF in PSPS performed with an electrode placed through the sacral hiatus were reported to be successful on pain in only 32% of patients. We have tried to improve the results by applying a new system to PRF.MethodsTen patients were treated with PRF application through a steerable epidural catheter with a reference electrode outside the foramen. This method was named “Optimization Current Flow” (OCF). The duty cycle of PRF was 2 × 10 msec and total exposure time was 150 s. Follow up was planned for 1, 3, and 6 months. The NRS score was considered to be the primary outcome.ResultsIn the first 10 patients treatment was successful (69% of the patients) at 6 months follow-up.ConclusionThis new modality of PRF in patients with PSPS seems to be superior to procedures done with a needle. Further prospective double-blind randomized long-term studies with a significant number of patients are required to validate this technique as there is a need to improve PRF results in PSPS.
Optimized miR-124 reporters uncover differences in miR-124 expression among neuronal populations in vitro
Authors: Lepolard Catherine , Rombaut Cynthia , Jaouen Florence , Borges Ana , Caccomo-Garcia Elodie , Popa Natalia , Gascon Eduardo 
Published: October 2023

IntroductionAlthough intensively studied in the last decades, how microRNAs (miRNAs) are expressed across different cell types in the brain remains largely unknown.MaterialsTo address this issue, we sought to develop optimized fluorescence reporters that could be expressed in precise cellular subsets and used to accurately quantify miR contents in vivo.ResultsFocusing on miR-124, we tested different reporter designs whose efficiency was confirmed in different in vitro settings including cell lines and primary neuronal cultures from different brain structures. Unlike previous reporters, we provide experimental evidence that our optimized designs can faithfully translate miR levels in vitro.DiscussionTools developed here would enable assessing miRNA expression at the single cell resolution and are expected to significantly contribute to future miRNA research in vivo.
Clinical study of renal artery cold perfusion combined with laparoscopic nephron retention in the treatment of complex renal angiomyolipoma
Authors: Zhu ChaoShuai , Yin HuaQi , Zhao ShiMing , Ma YongKang , Sun ZhengHui , Zhu MingKai , Du Zheng , Yang Tiejun 
Published: October 2023

ObjectiveThe aim of this study is to summarize the surgical experience of renal artery cold perfusion combined with laparoscopic nephron preserving surgery for the treatment of complex renal angiomyolipoma and to evaluate the safety and feasibility of this surgical protocol.Materials and methodsClinical data of nine patients who received renal artery cold perfusion combined with laparoscopic nephron preserving surgery for complex renal angiomyolipoma in our hospital from February 2017 to August 2020 were retrospectively analyzed. The study parameters included imaging findings, total renal function before and after surgery, glomerular filtration rate (GFR) of affected kidney before and after surgery, and related complications.ResultsEight of the nine patients successfully completed the operation, one patient was intolerant to renal artery balloon implantation, and the success rate of the operation was 88.89%. The mean maximum tumor diameter was 6.8 cm, and RENAL score was 7 points. Postoperative total renal function and GFR of the affected kidney had no significant changes compared with that before surgery, and imaging examination showed no tumor residue or recurrenceConclusionThis surgical procedure is safe and feasible for complex renal angiomyolipoma and can be used as a surgical option for renal hamartoma. The long-term effect needs to be confirmed by further studies.
Cause of death during nasopharyngeal carcinoma survivorship: a population-based analysis
Authors: Zhou Jie , Jiang Zhenyu , Li Yunhao , Shao Xuwen , Liao Haihong 
Published: October 2023

BackgroundRecently, the survival rate of nasopharyngeal carcinoma (NPC) patients has improved greatly due to developments in NPC treatments. But cause-specific mortality in NPC patients remains unclear. This study aims to investigate the common causes of death in NPC patients.MethodsEligible patients with NPC were included from the Surveillance, Epidemiology, and End Results (SEER) database. Standardized mortality ratios(SMRs) were calculated to compare death rates in NPC patients with those in the general population.ResultsA total of 3475 patients with NPC were included, of whom 1696 patients died during the follow-up period. 52.83% of deaths were caused by NPC, followed by other cancers (28.13%) and non-cancer causes (18.46%). The proportion of patients who died of NPC decreased over survival time. Moreover, non-cancer causes of death increase from 12.94% to 51.22% over time after 10 years of diagnosis. Heart diseases was the most common non-cancer cause of death in NPC patients.ConclusionsAlthough NPC remains the leading cause of death after NPC diagnosis, other non-NPC causes of death represent an increased number of death in NPC patients. These findings support the involvement of multidisciplinary care for follow-up strategy in NPC patients.
Protocol for a 20-year follow-up after a randomized controlled trial of a Mediterranean diet in pregnancy: maternal and offspring risk factors for cardiovascular disease
Authors: Troensegaard Hannibal , Khoury Janette , Westerberg Ane C. , Tonstad Serena , Roeters van Lennep Jeanine , Veierød Marit B. , Iversen Per Ole , Holven Kirsten B. , Retterstøl Kjetil 
Published: October 2023

BackgroundAn inadequate maternal diet during pregnancy can impair offspring health and may increase the risk of cardiovascular disease later in life. The purpose of the proposed study is to assess the risk factors associated with cardiovascular disease in both mothers and their offspring 20 years following their participation in a Mediterranean diet intervention trial during pregnancy.MethodsThe “Cardiovascular Risk Reduction Diet In Pregnancy” (CARRDIP) study was a randomized controlled trial performed between 1999 and 2001. The participants were randomized to adhere to either a Mediterranean diet or their regular diet during pregnancy. An extensive amount of data such as diet information, ultrasound measurements, anthropometry, and biomarkers from these mothers during pregnancy and their offspring in the neonatal period were collected. The mother–offspring pairs (n = 269) from the CARRDIP study will be invited to participate in a clinical examination and blood sample collection. This follow-up study, conducted 20 years after the original CARRDIP study, will investigate cardiovascular risk factors in mothers and offspring. The primary outcome will be the blood pressure of the offspring. In addition, the study will explore various aspects of cardiovascular health, including metabolic and inflammatory status, clinical history, and body composition of the participants.DiscussionPrevious studies investigating the effects of nutrition during pregnancy on maternal and offspring health have been either observational studies, animal studies, or randomized controlled trials with a follow-up period of less than 5 years. This project aims to study the long-term effects of dietary intervention during pregnancy on maternal and offspring cardiovascular risk markers.Clinical Trial RegistrationClinicaltrials.gov, identifier (NCT05030922).
Psychological impact of COVID-19 and determinants among Spanish university students
Authors: Cebrino Jesús , Portero de la Cruz Silvia 
Published: October 2023

BackgroundUniversity students are a vulnerable population and faced a significant psychological impact from the COVID-19 pandemic. Therefore, this study aimed to determine the level of fear of COVID-19 among university students and to evaluate the possible relationship between fear of COVID-19 and socio-demographic, health-related determinants, variables related to the COVID-19 and variables related to the psychological impact of the COVID-19 pandemic.MethodsWe conducted a cross-sectional study between December 2020 and December 2021 on a sample of 950 university students from two universities in southern Spain. Participants completed a form that collected socio-demographic, health-related and COVID-related variables, a validated questionnaire related to the psychological impact of the COVID-19 pandemic and the fear of COVID Scale (FCV-19S). Descriptive, inferential, and multivariable linear regression analyzes were conducted.ResultsThe mean FCV-19S score was 14.86 ± 5.16 points. The factors identified as predictors of FCV-19S were being female (p &lt; 0.001), holding religious beliefs (p = 0.04), living in towns with over 10,000 inhabitants (p &lt; 0.01), living with someone vulnerable to COVID-19 (p = 0.02), watching TV to keep informed about COVID-19 (p &lt; 0.01), believing in a low probability of surviving if infected with COVID-19 (p &lt; 0.001), having a higher level of death anxiety (p &lt; 0.001) and suffering from insomnia (p &lt; 0.001).ConclusionAn average fear of COVID-19 score of 14.86 ± 5.16 points has been found among university students in Spain. These findings can aid in identifying specific factors contributing to fear of COVID-19 and in developing coping strategies to alleviate the stress of the pandemic.