bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radiographic assessment of endodontic accidents at a Nigerian tertiary health institution: A one-year retrospective study
Authors: Ibhawoh LO  , Enyinnaya NS  , Enabulele JE  
Published: October 2023

Introduction: Dental treatment can produce iatrogenic injury to the tooth with endodontic procedural errors occurring during the various stages of endodontic treatment. This study determined the prevalence and pattern of endodontic accidents in clinical practice at a tertiary health center in Nigeria.
Methodology: This was a retrospective study of teeth treated with conventional hand-held file systems. Digital peri-apical working length, pre-obturation and post obturation radiographic images of teeth which received root canal treatment, were assessed for the presence or absence of errors. All errors present were recorded and data analysis was done using IBM SPSS version 22.0.
Results: The prevalence of procedural errors was 31.3% with ledges being the most prevalent error followed by transportation while gouging was the least encountered error. Majority (83.8%) of the errors occurred during root canal instrumentation. A higher proportion of molars had errors compared to the other types of teeth with the prevalence of errors increasing from incisors to premolars and then to molar teeth. The mandibular molars were found to be most frequently involved in procedural errors.
Conclusion: The prevalence of procedural errors seems high. Practitioners should show greater care during the canal preparation stage and to maintain the accuracy of the working length throughout the procedure, as errors which occur during canal preparation accounted for the vast majority of errors seen in this study. Special care should be taken when working on molars, which had a significantly higher error rate when compared to anterior teeth or premolars.
Penerapan Pencatatan Keuangan pada Usaha Mikro Kecil dan Menengah pada Perusahaan Jasa Advertising Berbasis SAK ETAP
Authors: Sundari Siti 
Published: October 2023

This research aimed to find out (1) how the implementation of the recording of financial reports based on SAK ETAP and (2) how the financial reporting on Advertising Service Company. Advertising Service Company is a UMKM which is involved in advertising services sectors and was still not able to implement financial reports based on SAK ETAP properly. This research uses qualitative case study methods. The sampling technique that is used is purposive sampling. This research was carried out in five steps, such as; 1) data collection, 2) data reduction, 3) data display, 4) data analysis, and 5) verification. The result of this research shows that; 1) In recording transaction, the owner not perform the recording based on SAK ETAP. The owner didn’t record a transaction rountinely, 2) the recording and reporting its still in manual way, 3) documents that found in the company is only a memorandum sale and the amount is limited, 4) the owner didn’t do the seperation of accounts between personal accounts and company’s accounts, 5) the owner doesn’t record all of the financial components of financial statements such as , income statement, statement of changes of equity, balance sheet, cash flow statement, and notes of the financial statements.
Implementation of Audit Procedures for Inventory Accounts at the Melati Putih Health Center
Authors: Listalia Dyta , Suryaningrum Diah Hari 
Published: October 2023

Health development in an area is the responsibility of the Community Health Center (Puskesmas) under the district or city health office. Providing health services is the main mission of puskesmas, this goal cannot be achieved without optimal inventory management. Supplies have an important role, namely, proper and sufficient supplies will ensure the availability of goods and medicines needed in health services. This study aims to describe the audit procedures carried out by the XYZ Public Accounting Firm (KAP) on inventory accounts at the Puskesmas Melati Putih, as well as how to overcome problems when conducting audit procedures. It is important to carry out inventory audit procedures at the Puskesmas Melati Putih to ensure the existence, accuracy, and completeness of supplies, as well as the fairness of reports owned by Puskesmas Melati Putih. In this study information collection through observation methods, documentation, and interviews with related staff. Based on these findings, the practice of recording and assessing the inventory of Puskesmas Melati Putih is in accordance with Financial Accounting Standards (SAK) and Government Accounting Standards (SAP). It's just that there are errors in recording inventory that cause differences between the balance sheet and inventory details arising from the difference in the inventory stock card with physical calculations, and the management and neatness of placing goods must be further improved to make it easier to find out inventory in the warehouse. Therefore, the recommendations given by KAP XYZ include improving records through correction journals, improving internal control, and improving inventory records.

DOI: https://doi.org/10.5281/zenodo.8415627
Engineering Mesoscopic 3D Tumor Models with a Self‐Organizing Vascularized Matrix
Authors: De Lorenzi Federica , Hansen Nadja , Theek Benjamin , Daware Rasika , Motta Alessandro , Breuel Saskia , Nasehi Ramin , Baumeister Julian , Schöneberg Jan , Stojanović Natalija , von Stillfried Saskia , Vogt Michael , Müller‐Newen Gerhard , Maurer Jochen , Sofias Alexandros Marios , Lammers Twan , Fischer Horst , Kiessling Fabian 
Published: October 2023

AbstractAdvanced in vitro systems such as multicellular spheroids and lab‐on‐a‐chip devices have been developed, but often fall short in reproducing the tissue scale and self‐organization of human diseases. A bioprinted artificial tumor model is introduced with endothelial and stromal cells self‐organizing into perfusable and functional vascular structures. This model uses 3D hydrogel matrices to embed multicellular tumor spheroids, allowing them to grow to mesoscopic scales and to interact with endothelial cells. It is shown that angiogenic multicellular tumor spheroids promote the growth of a vascular network, which in turn further enhances the growth of cocultivated tumor spheroids. The self‐developed vascular structure infiltrates the tumor spheroids, forms functional connections with the bioprinted endothelium, and can be perfused by erythrocytes and polystyrene microspheres. Moreover, cancer cells migrate spontaneously from the tumor spheroid through the self‐assembled vascular network into the fluid flow. Additionally, tumor type specific characteristics of desmoplasia, angiogenesis, and metastatic propensity are preserved between patient‐derived samples and tumors derived from this same material growing in the bioreactors. Overall, this modular approach opens up new avenues for studying tumor pathophysiology and cellular interactions in vitro, providing a platform for advanced drug testing while reducing the need for in vivo experimentation.
Direct Operando Visualization of Metal Support Interactions Induced by Hydrogen Spillover During CO2 Hydrogenation
Authors: Jenkinson Kellie , Spadaro Maria Chiara , Golovanova Viktoria , Andreu Teresa , Morante Joan Ramon , Arbiol Jordi , Bals Sara 
Published: October 2023

AbstractThe understanding of catalyst active sites is a fundamental challenge for the future rational design of optimized and bespoke catalysts. For instance, the partial reduction of Ce4+ surface sites to Ce3+ and the formation of oxygen vacancies are critical for CO2 hydrogenation, CO oxidation, and the water gas shift reaction. Furthermore, metal nanoparticles, the reducible support, and metal support interactions are prone to evolve under reaction conditions; therefore a catalyst structure must be characterized under operando conditions to identify active states and deduce structure‐activity relationships. In the present work, temperature‐induced morphological and chemical changes in Ni nanoparticle‐decorated mesoporous CeO2 by means of in situ quantitative multimode electron tomography and in situ heating electron energy loss spectroscopy, respectively, are investigated. Moreover, operando electron energy loss spectroscopy is employed using a windowed gas cell and reveals the role of Ni‐induced hydrogen spillover on active Ce3+ site formation and enhancement of the overall catalytic performance.
A Tunable Soft Silicone Bioadhesive for Secure Anchoring of Diverse Medical Devices to Wet Biological Tissue
Authors: Singh Manisha , Teodorescu Debbie L. , Rowlett Meagan , Wang Sophie X. , Balcells Mercedes , Park Clara , Bernardo Bruno , McGarel Sian , Reeves Charlotte , Mehra Mandeep R. , Zhao Xuanhe , Yuk Hyunwoo , Roche Ellen T. 
Published: October 2023

AbstractSilicone is utilized widely in medical devices for its compatibility with tissues and bodily fluids, making it a versatile material for implants and wearables. To effectively bond silicone devices to biological tissues, a reliable adhesive is required to create a long‐lasting interface. BioAdheSil, a silicone‐based bioadhesive designed to provide robust adhesion on both sides of the interface is introduced here, facilitating bonding between dissimilar substrates, namely silicone devices and tissues. The adhesive's design focuses on two key aspects: wet tissue adhesion capability and tissue‐infiltration‐based long‐term integration. BioAdheSil is formulated by mixing soft silicone oligomers with siloxane coupling agents and absorbents for bonding the hydrophobic silicone device to hydrophilic tissues. Incorporation of biodegradable absorbents eliminates surface water and controls porosity, while silane crosslinkers provide interfacial strength. Over time, BioAdheSil transitions from nonpermeable to permeable through enzyme degradation, creating a porous structure that facilitates cell migration and tissue integration, potentially enabling long‐lasting adhesion. Experimental results demonstrate that BioAdheSil outperforms commercial adhesives and elicits no adverse response in rats. BioAdheSil offers practical utility for adhering silicone devices to wet tissues, including long‐term implants and transcutaneous devices. Here, its functionality is demonstrated through applications such as tracheal stents and left ventricular assist device lines.
Scalable Printing of Metal Nanostructures through Superluminescent Light Projection
Authors: Choi Jungho , Saha Sourabh K. 
Published: October 2023

AbstractDirect printing of metallic nanostructures is highly desirable but current techniques cannot achieve nanoscale resolutions or are too expensive and slow. Photoreduction of solvated metal ions into metallic nanoparticles is an attractive strategy because it is faster than deposition‐based techniques. However, it is still limited by the resolution versus cost tradeoff because sub‐diffraction printing of nanostructures requires high‐intensity light from expensive femtosecond lasers. Here, this tradeoff is overcome by leveraging the spatial and temporal coherence properties of low‐intensity diode‐based superluminescent light. The superluminescent light projection (SLP) technique is presented to rapidly print sub‐diffraction nanostructures, as small as 210 nm and at periods as small as 300 nm, with light that is a billion times less intense than femtosecond lasers. Printing of arbitrarily complex 2D nanostructured silver patterns over 30 µm × 80 µm areas in 500 ms time scales is demonstrated. The post‐annealed nanostructures exhibit an electrical conductivity up to 1/12th that of bulk silver. SLP is up to 480 times faster and 35 times less expensive than printing with femtosecond lasers. Therefore, it transforms nanoscale metal printing into a scalable format, thereby significantly enhancing the transition of nano‐enabled devices from research laboratories into real‐world applications.
Critical levels and nitrogen fertilizer equivalencies for grain protein in winter wheat
Authors: Long Dan S. , Reardon Catherine L. , Adams Curtis B. 
Published: October 2023

AbstractPrecision nitrogen (N) application methods have been developed for dryland wheat that utilize site‐specific measurements of grain protein concentration (GPC) to determine N fertilizer recommendations for the next season. The objectives of this study were to determine the critical protein level and N equivalent to a unit change in GPC from relationships between GPC, and grain yield or plant‐available N in soft white winter wheat (SWW, Triticum aestivum L.), and assess the consistency of these relationships across SWW cultivars grown under a wide range of precipitation. A 3‐year study was undertaken near two sites: Lexington (225 mm of mean annual precipitation) and Adams (450 mm) in Oregon. Differences in precipitation and N fertilization rates between sites were used to induce variability in grain yield and GPC of four cultivars. A critical protein concentration of 117.5 g kg−1 was defined by Cate–Nelson analysis of scatter plots of relative yield versus GPC. Critical protein among cultivars ranged between 105 and 118 g kg−1 suggesting that 117.5 g kg−1 might be used as a general indicator of N sufficiency. Slopes of the regression of available N on GPC were consistent across cultivars and revealed that 4.2–8.4 kg N ha−1 is equivalent to a unit change protein (1 g kg−1) in lower precipitation areas of the region where SWW is under water stress during grain filling. This information is useful in calculating the N to apply from the GPC in the previous season to meet crop requirements in the next season.
The sulfur species in hot rocky exoplanet atmospheres
Authors: Janssen L. J. , Woitke P. , Herbort O. , Min M. , Chubb K. L. , Helling Ch. , Carone L. 
Published: October 2023

AbstractThe first JWST observations of hot Jupiters showed an unexpected detection of SO in their hydrogen‐rich atmospheres. We investigate how much sulfur can be expected in the atmospheres of rocky exoplanets and which sulfur molecules can be expected to be most abundant and detectable by transmission spectroscopy. We run thermochemical equilibrium models at the crust–atmosphere interface, considering surface temperatures 500–5000 K, surface pressures 1–100 bar, and various sets of element abundances based on common rock compositions. Between 1000 and 2000 K, we find gaseous sulfur concentrations of up to 25% above the rock in our models. SO, SO, HS, and S are by far the most abundant sulfur molecules. SO
shows potentially detectable features in transmission spectra at about 4 m, between 7 and 8 m, and beyond 15 m. In contrast, the sometimes abundant HS molecule is difficult to detect in these spectra, which are mostly dominated by HO and CO. Although the molecule PS only occurs with concentrations  ppm, it can cause a strong absorption feature between 0.3 and 0.65 m in some of our models for high surface pressures. The detection of sulfur molecules would enable a better characterization of the planetary surface.
The novel technique of drainage stenting using a tapered sheath dilator in endoscopic ultrasound‐guided biliary drainage
Authors: Kato Akihisa , Yoshida Michihiro , Hori Yasuki , Kachi Kenta , Sahashi Hidenori , Toyohara Tadashi , Adachi Akihisa , Kuno Kayoko , Kito Yusuke , Kataoka Hiromi 
Published: October 2023

AbstractDuring endoscopic ultrasound‐guided biliary drainage (EUS‐BD), there is a risk for bile leakage until stent deployment, which can result in severe peritonitis, particularly when passing a drainage stent becomes challenging despite tract dilation. There is no established method or dedicated device to optimize EUS‐BD. Therefore, we have developed a novel stent deployment technique using the tapered sheath dilator. To address the safety and technical aspects of the EUS‐BD technique, we retrospectively analyzed 11 consecutive patients who underwent EUS‐BD using the tapered sheath dilator. The procedure involved the insertion of a guidewire, followed by mechanical dilation using the tapered sheath dilator. Subsequently, the inner catheter was removed and drainage stents (up to 6 Fr in diameter) were deployed through the outer sheath. We found a 100% technical success rate for tract dilation and stent deployment; moreover, all patients achieved clinical success. The median time for dilation was 40 s (range, 8–198), whereas the median time from dilation to stent deployment was 10 min (range, 6–19). Notably, no cases of bile leakage or peritonitis were observed. In conclusion, the use of the integrated device for tract dilation and stent delivery system might provide a safe and straightforward technique for drainage stenting during EUS‐BD.
Evaluation of collaborative mental health services in Latin America: Theoretical and methodological basis
Authors: Sapag Jaime C. , Rush Brian 
Published: October 2023

AbstractObjectivesApproaches to collaborative mental health care (CMHC) have been implemented in many countries to strengthen the accessibility and delivery of mental health services in primary care. However, there are not well‐defined frameworks to evaluate CMHC models. The purpose of this article is to identify, contextualize and discuss relevant health services research approaches, theory, and evaluation models for the development of an appropriate evaluation framework in order to foster effective CMHC in Latin America.MethodsA comprehensive literature review informed a critical analysis of relevant theories and alternative methods to be considered in the development of the framework.ResultsSpecific health services research frameworks are discussed in the context of evaluating CMHC. Two theoretical perspectives ‐ collaboration theory and systems theory – and three evaluation models‐ realistic, developmental and collaborative ‐ are analyzed in terms of their relevance. Methodological implications are identified.ConclusionAn appropriate evaluation framework for CMHC in Latin America needs to reflect theoretical and contextual considerations and relevant evaluation approaches and methods, including key dimensions and attributes/variables, core indicators, and recommendations for implementation.
Efficacy and Safety of Single Doses of Intramuscular Ketorolac Tromethamine Compared with Meperidine for Postoperative Pain
Authors: Stanski Donald R. , Cherry Carter , Bradley Rita , Sarnquist Frank H. , Yee James P. 
Published: October 2023

Ketorolac tromethamine, a potent nonnarcotic prostaglandin synthetase‐inhibiting analgesic, was compared with meperidine for relief of moderate to severe postoperative pain. In a double‐blind, randomized study, 125 patients received single intramuscular doses of ketorolac 30 or 90 mg or meperidine 50 or 100 mg. The degree of pain and pain relief were quantified verbally and with visual analog scales at baseline and 30 minutes, then hourly for 6 hours. Ketorolac 30 and 90 mg were significantly superior to meperidine 50 mg in six of nine efficacy measures.The onset of and peak analgesic effect of both doses of ketorolac and of meperidine were equivalent. Compared with both doses of meperidine, the two doses of ketorolac exhibited significantly longer duration of analgesic effect, as measured by the percentage of patients who terminated the study because of inadequate pain relief. The frequency of side effects was not significantly different between the drugs. The prolonged efficacy of intramuscular ketorolac combined with the reduced risk of respiratory depression suggest an important use of this drug for the relief of postoperative pain.
Hemodynamic Effects of Two Intravenous Doses of Ketorolac Tromethamine Compared with Morphine
Authors: Camu Frederic , Van Overberge Luc , Bullingham Roy , Lloyd Julia 
Published: October 2023

The cardiovascular effects of intravenous administration of ketorolac tromethamine 10 and 90 mg were measured and compared with those of morphine sulfate 10 mg in 18 anesthetized patients after major vascular surgery. Morphine caused a significant reduction in mean arterial pressure, left cardiac work index, and left ventricular stroke work index. Stroke volume index, cardiac output, and pulmonary artery pressures decreased to a lesser extent. Ketorolac at either dose was not associated with any significant change in cardiac and hemodynamic parameters.The data suggest that even high doses of the drug may be safely administered in clinical situations where hypotension is disadvantageous or where reduction in afterload is not a specific therapeutic aim.
Functional Aspects of Human Sperm Binding to the Zona Pellucida Using the Hemizona Assay
Authors: CODDINGTON CHARLES C. , FRANKEN DANIEL R. , BURKMAN LANI J. , OOSTHUIZEN W. T. , KRUGER THINUS , HODGEN GARY D. 
Published: October 2023

AbstractThe hemizona assay (HZA) has facilitated investigations of sperm function in relation to zona pellucida binding. In this study, the authors examined: 1) the association between hyperactivated sperm motility and HZA binding; 2) the binding kinetics and efficiency of sperm from subfertile men; and 3) the influence of sperm freezing and thawing on binding capacity. For each HZA, a nonviable human oocyte was cut into equal zona hemispheres. The mean number of bound sperm and the incidence of hyperactivation were significantly greater for samples of sperm from fertile men compared with sperm from subfertile men (P < 0.05). Subfertile sperm had a binding curve that paralleled the curve for fertile sperm, although the magnitude of binding was markedly reduced. Freezing and thawing of sperm from fertile samples impaired their capacity to bind to the zona pellucida. The HZA binding efficiency was reduced by 30%, although the binding curves for fresh versus frozen samples remained parallel.