bluuebunny/crossref_metadata_2025_split huggingface dataset:
The co-construction and emotion management of hope within psychosis services
Authors: Brown Patrick , Scrivener Amanda , Calnan Michael 
Published: January 2024

IntroductionThere is a growing acknowledgement of the salience of hope for mental health service-users, in influencing care outcomes and recovery. Understandings of the processes through which hopes are co-constructed, alongside specific conceptualisations of experiences of hoping, remain limited however.MethodsThis qualitative study explored how a range of stakeholders experienced and dealt with uncertainty within three purposively selected psychosis services in southern England. In this article we focus particularly on the co-construction of hope within participants' narratives and how this emotion work shaped experiences of hoping. In-depth interviews (n = 23) with service-users, professionals, managers and other stakeholders were analysed following a phenomenological approach.FindingsHope was spontaneously identified by participants as a fundamental mechanism through which service-users and professionals managed uncertainty when vulnerable. Professionals were influential in shaping users' hopes, both intentionally and unwittingly, while some professionals also referred to managing their own hopes and those of colleagues. Such management of expectations and emotions enabled motivation and coping amidst uncertainty, for users and professionals, but also entailed difficulties where hope was undermined, exaggerated, or involved tensions between desires and expectations.DiscussionWhereas, hope is usually reflected in the caring studies literature as distinctly positive, our findings point to a more ambivalent understanding of hope, as reflected in the accounts of both service-users and professionals where elevated hopes were described as unrealistic and harmful, to the well-being of professionals as well as of service-users. It is concluded that a greater awareness within care contexts of how hopes are co-constructed by professionals and service-users, explicitly and implicitly, can assist in improving health care and healthcare outcomes.
Astrocyte DNA damage and response upon acute exposure to ethanol and corticosterone
Authors: Reyes-Ábalos Ana Laura , Álvarez-Zabaleta Magdalena , Olivera-Bravo Silvia , Di Tomaso María Vittoria 
Published: January 2024

Introduction: Astrocytes are the glial cells responsible for brain homeostasis, but if injured, they could damage neural cells even deadly. Genetic damage, DNA damage response (DDR), and its downstream cascades are dramatic events poorly studied in astrocytes.Hypothesis and methods: We propose that 1 h of 400 mmol/L ethanol and/or 1 μmol/L corticosterone exposure of cultured hippocampal astrocytes damages DNA, activating the DDR and eliciting functional changes. Immunolabeling against γH2AX (chromatin DNA damage sites), cyclin D1 (cell cycle control), nuclear (base excision repair, BER), and cytoplasmic (anti-inflammatory functions) APE1, ribosomal nucleolus proteins together with GFAP and S100β plus scanning electron microscopy studies of the astrocyte surface were carried out.Results: Data obtained indicate significant DNA damage, immediate cell cycle arrest, and BER activation. Changes in the cytoplasmic signals of cyclin D1 and APE1, nucleolus number, and membrane-attached vesicles strongly suggest a reactivity like astrocyte response without significant morphological changes.Discussion: Obtained results uncover astrocyte genome immediate vulnerability and DDR activation, plus a functional response that might in part, be signaled through extracellular vesicles, evidencing the complex influence that astrocytes may have on the CNS even upon short-term aggressions.
Feasibility of in-home electroencephalographic and actigraphy recordings in dogs
Authors: Folkard Emily , McKenna Charly , Monteith Gabrielle , Niel Lee , Gaitero Luis , James Fiona May Keir 
Published: January 2024

IntroductionIdiopathic epilepsy is a prevalent neurological disease in dogs. Dogs with epilepsy often present with behavioral comorbidities such as aggression, anxiety, and fear. These behaviors are consistent with pre, post, or interictal behaviors, prodromal changes, seizure-precipitating factors, or absence and focal seizures. The overlap in behavior presentations and lack of objective research methods for quantifying and classifying canine behavior makes determining the cause difficult. Behavioral comorbidities in addition to the task of caring for an epileptic animal have a significant negative impact on dog and caregiver quality of life.MethodsThis pilot study aimed to assess the feasibility of a novel technology combination for behavior classification and epileptic seizure detection for a minimum 24-h recording in the dog's home environment. It was expected that combining electroencephalography (EEG), actigraphy, and questionnaires would be feasible in the majority of trials. A convenience sample of 10 community-owned dogs was instrumented with wireless video-EEG and actigraphy for up to 48 h of recording at their caregiver's home. Three questionnaires (maximum 137 questions) were completed over the recording period by caregivers to describe their dog's everyday behavior and habits.ResultsSix of the 10 included dogs had combined EEG and actigraphy recordings for a minimum of 24 h.DiscussionThis shows that in-home EEG and actigraphy recordings are possible in community-owned dogs and provides a basis for a prospective study examining the same technology combination in a larger sample size.
Clinical and pathological observation of conversion therapy for malignant peritoneal mesothelioma: a case report and literature review
Authors: Deng Minying , Zhang Xinyi , Xu Chen , Luo Rongkui , Chen Lingli , Zhou Yuhong , Hou Yingyong 
Published: January 2024

Background: Malignant mesothelioma (MM) is a tumor originating from the pleura, peritoneum, or pericardial cavity. It is divided into diffuse and localized malignant mesothelioma, with four subtypes in diffuse MM: epithelioid, sarcomatoid, desmoplastic, and biphasic, with biphasic being less common. The onset of this tumor is insidious, and the prognosis is extremely poor in some cases, with a median survival of 6–18 months and no standard treatment options in the past.Aims: We report a case of peritoneal malignant mesothelioma that was successfully treated with transformative therapy. We also review the literature in the hope of providing reference for the treatment and pathological diagnosis of such patients.Methods: The case of the peritoneal malignant mesothelioma was processed and reported in the routine manner for biopsy specimens at different stages.Results and conclusion: We report a case of a malignant tumor originating in the hepatorenal recess, which was diagnosed as biphasic malignant mesothelioma through a biopsy. Immunohistochemical testing showed PD-L1 expression. After multidisciplinary discussion, the patient received transformative treatment, including a trial of combined immunotherapy. The tumor significantly shrank, and the patient obtained a chance for curative surgical resection. Microscopic examination showed significant collagenization in the lesion area, with almost no residual tumor. After 19 months of comprehensive treatment, the patient developed multiple fluffy opacities under the pleura of both lungs. Transthoracic core needle biopsy under CT guidance, the pathology showed organizing pneumonia, considering it as delayed interstitial pneumonitis due to immunotherapy based on previous treatment history. Successful comprehensive treatment was achieved for this case of peritoneal malignant mesothelioma, and the patient has been alive without evidence of disease for 33 months, with long-term follow-up. In this process, the pathologist had three opportunities for pathological diagnosis, which required understanding the patient’s medical history, being attentive to the clinical purpose of the specimen, and providing accurate responses to morphological changes at different stages, along with corresponding descriptions and diagnoses to provide effective information for clinical treatment.
The Specificities of Lysophosphatidic Acid Acyltransferase and Fatty Acid Desaturase Determine the High Content of Myristic and Myristoleic Acids in Cyanobacterium sp. IPPAS B-1200
Authors: Starikov Alexander Y. , Sidorov Roman A. , Mironov Kirill S. , Los Dmitry A. 
Published: January 2024

The cyanobacterial strain Cyanobacterium sp. IPPAS B-1200 isolated from Lake Balkhash is characterized by high relative amounts of myristic (30%) and myristoleic (10%) acids. The remaining fatty acids (FAs) are represented mainly by palmitic (20%) and palmitoleic (40%) acids. We expressed the genes for lysophosphatidic acid acyltransferase (LPAAT; EC 2.3.1.51) and Δ9 fatty acid desaturase (FAD; EC 1.14.19.1) from Cyanobacterium sp. IPPAS B-1200 in Synechococcus elongatus PCC 7942, which synthesizes myristic and myristoleic acids at the level of 0.5–1% and produces mainly palmitic (~60%) and palmitoleic (35%) acids. S. elongatus cells that expressed foreign LPAAT synthesized myristic acid at 26%, but did not produce myristoleic acid, suggesting that Δ9-FAD of S. elongatus cannot desaturate FAs with chain lengths less than C16. Synechococcus cells that co-expressed LPAAT and Δ9-FAD of Cyanobacterium synthesized up to 45% palmitoleic and 9% myristoleic acid, suggesting that Δ9-FAD of Cyanobacterium is capable of desaturating saturated acyl chains of any length.
Conserving Marine Forests: Assessing the Effectiveness of a Marine Protected Area for Cystoseira sensu lato Populations in the Central Mediterranean Sea
Authors: Mancuso Francesco Paolo , Sarà Gianluca , Mannino Anna Maria 
Published: January 2024

Marine Protected Areas (MPAs) are vital for biodiversity conservation, yet their effectiveness in preserving foundation seaweeds remains understudied. This study investigates the diversity and distribution of Cystoseira sensu lato (including Cystoseira, Ericaria, and Gongolaria, hereafter referred to as Cystoseira s.l.) populations in an MPA located in the central Mediterranean Sea, comparing them with those in two unprotected sites. We hypothesized MPA Cystoseira s.l. populations would display higher diversity and structure compared to outside unprotected sites. Results revealed a total of 19 Cystoseira s.l. species at depths of 0–20 m, with the MPA exhibiting a higher diversity than unprotected sites. Thus, MPAs can play a crucial role in fostering the diversity of Cystoseira s.l. populations. However, no significant differences were observed among the MPA’s protection zones, raising questions about the zoning effectiveness. Additionally, our survey uncovered a substantial presence of non-indigenous seaweeds within the MPA. In conclusions, while MPAs improved Cystoseira s.l. diversity compared to unprotected sites, the varying efficacy of protection within MPA zones suggested a necessity for site-specific conservation strategies. The presence of non-indigenous seaweeds emphasizes ongoing challenges. This study provides a baseline for understanding Cystoseira s.l. population dynamics, crucial for future monitoring and conservation efforts in the face of global change.
Implementasi Model Evaluasi Context, Input, Process, and Product (CIPP) pada Program Pengenalan Lapangan Persekolahan (PLP) bagi Calon Guru Bahasa Inggris
Authors: Rima Rosmania , Anriani Nurul 
Published: January 2024

Program Pengenalan Lapangan Persekolahan (PLP) adalah kegiatan yang wajib diikuti oleh calon guru di Fakultas Keguruan dan Ilmu Pendidikan Universitas Sultan Ageng Tirtayasa, tidak terkecuali yang berasal dari Program Studi Pendidikan Bahasa Inggris, karena PLP ini merupakan salah satu aktivitas yang termasuk dalam mata kuliah wajib di kurikulum. PLP ini memiliki tujuan melatih mahasiswa calon guru untuk memiliki pengetahuan serta keterampilan dalam perencanaan, pelaksanaan dan evaluasi pembelajaran agar mahasiswa memiliki bekal awal untuk menjadi guru yang professional di masa mendatang. PLP ini telah menjadi agenda rutin pada semester geanjil di setiap tahun akademik dan pelaksanaannya direncanakan dan dipersiapkan dengan baik, namun masih saja terjadi hambatan dan tantangan bersifat teknis dan operasional. Hasil evaluasi pelaksanaan kegiatan PLP 2023 dilihat dari aspek konteks (konteks) terdapat permasalahan dalam mencapai tujuan yang ingin dicapai. Dalam hal input, ada beberapa faktor yang memengaruhi pelaksanaan PLP yaang berasal dari DPL, Kepala Sekolah, Guru Pamong dan Mahasiswa itu sendiri. Dari aspek proses, program PLP ini terdiri dari empat tahap yaitu kegiatan observasi, pelaksanaan, pengawasan, dan pelaporan. Dilihat dari aspek produk program ini menghasilkan luaran dalam bentuk peningkatan kemampuan kognitif, afektif, psikomotorik, dan sosial mahasiswa praktikan.
MODEL PROBLEM BASED LEARNING PADA MATA PELAJARAN FIKIH DI MADRASAH TSANAWIYAH
Authors: Sari Erni Anita , Wahidin Wahidin 
Published: January 2024

Tujuan mempelajari Fiqih adalah untuk memberikan pemahaman kepada siswa tentang berbagai hukum Syariah atau Islam dan berbagai aturan kehidupan manusia. Memahami permasalahan tersebut bukanlah hal yang mudah, apalagi bagi siswa Madrasah Tsanawiyah yang notabene harus selalu diberikan contoh dan permasalahan spesifik yang dapat meningkatkan pemahaman siswa. Tujuan penelitian ini adalah untuk mengetahui penerapan model pembelajaran berbasis masalah pada mata pelajaran fiqh di Madrasah Tsanawiyah Pancasila. Penelitian ini merupakan penelitian kualitatif yang berlokasi di Madrasah Tsanawiyah Pancasila Salatiga. Sumber data penelitian diperoleh dari data primer dan data sekunder. Metode pengumpulan data menggunakan wawancara, dokumentasi dan observasi, sedangkan metode analisis data menggunakan metode analisis deskriptif. Berdasarkan hasil penelitian yang dilakukan peneliti dapat disimpulkan bahwa penerapan pembelajaran fiqh dengan model pembelajaran berbasis masalah membantu meningkatkan pemahaman anak terhadap materi fiqh, karena pembelajaran selalu bertujuan untuk menyajikan permasalahan sederhana. , tapi mampu untuk memberikan pemahaman yang cukup spesifik terhadap siswa. Selain itu dengan dimunculkannya masalah-masalah ternyata dapat merangsang siswa lebih semangat dalam mengikuti proses pembelajaran.
Ocena stanu technicznego zabytkowych dworów – propozycja standaryzacji dokumentacji
Authors: Kendzierawska Weronika , Trochonowicz Maciej 
Published: January 2024

W przeciwieństwie do założeń pałacowych, które w większości przypadków na Lubelszczyźnie znajdują się w stanie technicznym co najmniej dobrym, znaczna część dworów jest w stanie co najwyżej dostatecznym. Obiekty dworskie ze względu na dużo mniejszą wartość historyczną i zabytkową, wyraźnie gorszą jakość materiałów oraz skomplikowany stan własnościowy, w dużej części popadły i nadal popadają w ruinę. Przeprowadzone analizy wykazały, że na stosunkowo niewielkim obszarze województwa lubelskiego znajduje się szereg obiektów wymagających szeroko zakrojonych prac projektowych i remontowych. Wszystkie te prace poprzedzone muszą być szczegółową analizą stanu technicznego. Dokumentacja taka powinna zawierać: aktualne inwentaryzacje, opisy techniczne, oceny stanu technicznego, podstawowe badania in situ oraz laboratoryjne. Artykuł niniejszy jest próbą standaryzacji wymienionej dokumentacji. Propozycja ta została przedstawiona na przykładzie XX-wiecznego dworu w miejscowości Zamieście, dla którego opracowana została dokumentacja rysunkowa i fotograficzna, wykonane zostały badania wilgotnościowe i mykologiczne oraz sporządzona szczegółowa ocena stanu technicznego.
Pengaruh Technology Acceptance Model (TAM) terhadap Customer Satisfaction dalam Bertransaksi menggunakan Layanan Mobile Payment Dana (Studi Kasus: Seluruh Pengguna Dana di Kota Pekanbaru)
Authors: Ramadan Citra Sari , Efnita Yul 
Published: January 2024

Adopsi dan adaptasi para peneliti terhadap gagasan Technology Acceptance Capital berkembang seiring dengan pertumbuhan teknologi informasi. Technology Acceptance Capital memainkan peran penting dalam membantu para pelaku bisnis di pasar e-commerce dengan mengembangkan teknologi digitalisasi. Pelanggan masih belum memanfaatkan teknologi modern yaitu pembayaran mobile. Persepsi utilitas dan kenyamanan diperiksa oleh model penerimaan teknologi sebagai jenis niat pengguna. Selain semakin banyaknya masyarakat Indonesia yang menggunakan smartphone dan internet, pemerintah juga berharap dapat mendorong lebih banyak orang untuk memanfaatkan pembayaran mobile karena merupakan cara yang sangat baik bagi Indonesia untuk melakukan pembayaran. Saat ini, Dana merupakan metode pembayaran e-wallet yang relatif baru di masyarakat. Karena aplikasi Dana masih dalam tahap pengembangan, dibutuhkan lebih banyak penelitian untuk membuatnya menarik bagi kaum milenial. Partisipan dalam penelitian ini adalah penduduk Pekanbaru, Indonesia yang menggunakan Dana. Penelitian ini menggunakan smartPLS versi 3 untuk analisis data.
Answering High-precision Problems for LLMs by Combining Text2code
Authors: Guo Tong 
Published: January 2024

The current large language models (LLMs) mainly lacks this capability:
answering high-precision questions/prompts. LLMs is actually a powerful
fuzzy memory system that makes it difficult to answer high-precision
questions. The results of code execution is a kind of high-precision
answer. And expert system applications need to answer these kinds of
questions. In this paper, to solve the above problem, We propose a
design of LLMs combined with the text2code approach.
The Role of Mothers in Building the Great Historical Islamic Personalities
Authors: Khushi Muhammad Tahira Jabeen , Hassan Syeda Muneeba , Al-Azhari Abdul Wahab Jan 
Published: January 2024

Islamic history has immortalized immortal mothers who were symbols of Islam. Their concern was the support of Islam, and the biography presented shining examples of mothers who were generous sources and whose children were the fruits of their cultivation. They were mothers who knew the status of motherhood, the role of the mother in sacrifice and Jihad, and the importance of working on the formation of the Muslim home and raising children armed with the light of knowledge working on the advancement of their religion. Where are the pioneers of the renaissance of motherhood among these models today…? Was the status of the mother - which many people neglected due to the weakness of religious faith - to be restricted to celebrating her one day a year? In this article, we will learn about some shining models from mothers of scholars and venerable preachers who greatly served Islam and spread beneficial knowledge…Perhaps these models will be a shining beacon for mothers today so that these models will guide today‘s mothers in how to raise their children in the light of important Islamic values and meanings.
Geografías artificiales y funcionales de la sostenibilidad: producción de problemas y soluciones
Authors: Jiménez Corrales Andrés 
Published: January 2024

La sostenibilidad es un concepto globalizado que ha constituido un recurso activado por diversos actores con el propósito de diseñar y adecuar proyectos y acciones para fines particulares. Este artículo propone, a partir de un profundo análisis documental, un acercamiento a las geografías artificiales y funcionales que la sostenibilidad permite gestar para la reproducción del capitalismo. Para ello se utilizará el caso del Banco Interamericano de Desarrollo (BID), específicamente lo que fue articulado dentro de la Iniciativa de Ciudades Emergentes y Sostenibles (ICES), para comprender los usos políticos de la sostenibilidad y sus posibles impactos en las transformaciones territoriales. Se concluye que el BID es un actor que, haciendo uso del discurso de la sostenibilidad, diseñó y puso en marcha una iniciativa que busca materializar una ciudad competitiva para los negocios empresariales y para el mercado instrumentalizando un proceso de neoliberalización urbana en América Central.
Latihan Relaksasi Nafas Dalam Terhadap Penurunan Skala Nyeri Pada Ibu Post Sectio Caesarea
Authors: - Rina Mariani 
Published: January 2024

Masalah pasien post operasi section caesaria (SC) yang sering muncul adalah nyeri. Nyeri terutama dirasakan pada hari pertama dan kedua, sehingga pasien membutuhkan bantuan pemenuhan kebutuhan sehari-hari. Penelitian ini bertujuan mengetahui pengaruh relaksasi nafas dalam terhadap nyeri pasien post sc. Penelitian dilaksanakan di RSUD Ryacudu pada Juli-Oktober 2018. Desain penelitian quasy experiment dengan rancangan pre-post test design with control group. Sampel penelitian 78 responden yang dibagi menjadi dua, yaitu kelompok intervensi dan kelompok kontrol. Variable independen yang diteliti adalah relaksasi nafas dalam sebagai variabel independent dan nyeri sebagai variabel dependent. Analisis yang digunakan adalah uji t test independen. Hasil penelitian, 70,5% umur responden 20-35 tahun, 55,1% pendidikan menengah, 66,7% paritas pertama, dan 73,1% pengalaman operasi pertama. Adanya penurunan rata-rata skor nyeri pada kelompok intervensi dari 6,23 menjadi 3,41dan pada kelompok kontrol dari 5,64 menjadi 4,59. Hasilnya ada pengaruh signifikan latihan relaksasi nafas dalam terhadap penurunan skala nyeri pasien post operasi SC, p=0,000. Pemberian relaksasi nafas dalam sangat tepat untuk pasien post operasi SC.
Hubungan Riwayat Stroke terhadap Kemandirian Pasien
Authors: Widakdo Giri , Naryati  , Nuraenah  , Aisyah  , Kusumo Waluyo Ineke , Dian Rusdiana  , Fathia Inasya Ayuningtyas  
Published: January 2024

Penelitian bertujuan mengetahui hubungan riwayat stroke terhadap kemandirian pasien di Rumah Sakit Islam Jakarta. Metode yang digunakan adalah deskiptif analitik dengan pendekatan crossectional. Analisis regresi logistik ganda (multivariat) menunjukkan bahwa pasien dengan serangan stroke berulang berresiko mengalami penurunan kemandirian sebesar 3,95 kali dibanding pada pasien dengan serangan stroke pertama kali. Kesimpulan: terdapat hubungan riwayat stroke dengan kemandirian setelah dikontrol oleh umur, jenis kelamin dan masalah kognitif pasien. Pasien stroke dengan riwayat serangan pertama kali dapat mengantisipasi dan mencegah kejadian serangan stroke berulang dari berbagai faktor yang menyebabkannya guna mengurangi penurunan kemandiriannya.
Infecciones asociadas a catéter venoso central en adultos en proceso de hemodiálisis
Authors: Silva-Cázares Macrina Beatriz , Escamilla-Reta Zobeida América , Lozano-Zúñiga María Magdalena , Hernandez Nava Nereyda 
Published: January 2024

Introducción: El catéter venoso central utilizado para hemodiálisis es la alternativa para los pacientes que se encuentran padeciendo insuficiencia renal crónica, en donde intervienen los profesionales de enfermería. Objetivo: Identificar la prevalencia de infecciones relacionada al catéter venoso central en pacientes con hemodiálisis de una clínica en México. Metodología: Estudio cuantitativo retrospectivo y descriptivo. La fuente de información fueron expedientes de la población total de pacientes atendidos en el año 2018 que correspondió a 29 usuarios y acciones epidemiológicas realizadas en el periodo de estudio y resultados reportadas en la bitácora de jefe de enfermería del área de hemodiálisis Resultados: Se encontró con un 43% staphylococcus epidermidis, el 14% de los casos de bacteriemia relacionada a catéter fue relacionada a bacteriemias nosocomiales; Se realizó cultivo de manos de todo el personal de enfermería en los diferentes turnos reportando la presencia de staphylococcus epidermidis en 60% del personal y staphylococcus coagulasa negativa en 60% del mobiliario del área de hemodiálisis. Conclusión: Se evidenció la necesidad de reforzar las medidas la prevención de infecciones relacionadas al catéter venoso central en los procedimientos de manipulación, incluyendo la unificación de los protocolos de asepsia y manejo de accesos vasculares permanentes por el personal de la salud.