bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gradient porous structures of mycelium: a quantitative structure–mechanical property analysis
Authors: Olivero Eric , Gawronska Elzbieta , Manimuda Praveena , Jivani Devyani , Chaggan Faemia Zullfikar , Corey Zachary , de Almeida Thaicia Stona , Kaplan-Bie Jessica , McIntyre Gavin , Wodo Olga , Nalam Prathima C. 
Published: November 2023

AbstractGradient porous structures (GPS) are characterized by structural variations along a specific direction, leading to enhanced mechanical and functional properties compared to homogeneous structures. This study explores the potential of mycelium, the root part of a fungus, as a biomaterial for generating GPS. During the intentional growth of mycelium, the filamentous network undergoes structural changes as the hyphae grow away from the feed substrate. Through microstructural analysis of sections obtained from the mycelium tissue, systematic variations in fiber characteristics (such as fiber radii distribution, crosslink density, network density, segment length) and pore characteristics (including pore size, number, porosity) are observed. Furthermore, the mesoscale mechanical moduli of the mycelium networks exhibit a gradual variation in local elastic modulus, with a significant change of approximately 50% across a 30 mm thick mycelium tissue. The structure-property analysis reveals a direct correlation between the local mechanical moduli and the network crosslink density of the mycelium. This study presents the potential of controlling growth conditions to generate mycelium-based GPS with desired functional properties. This approach, which is both sustainable and economically viable, expands the applications of mycelium-based GPS to include filtration membranes, bio-scaffolds, tissue regeneration platforms, and more.
Heat sink effects in thyroid bipolar radiofrequency ablation: an ex vivo study
Authors: Klimek Konrad , Mader Nicolai , Happel Christian , Sabet Amir , Grünwald Frank , Groener Daniel 
Published: November 2023

AbstractThe study aimed to investigate heat sink effects in radiofrequency ablation (RFA) under thyroid-specific conditions. In an ex vivo model, bovine thyroid lobes were ablated using bipolar RFA with 2.0 kJ energy input at a power level set to 10 W (n = 35) and 25 W (n = 35). Glass vessels (3.0 mm outer diameter) placed within the ablation zone were used to deliver tissue perfusion at various flow rates (0, 0.25, 0.5, 1, 5, 10, 20 ml/min). Temperature was measured in the proximity of the vessel (Tv) and in the non-perfused contralateral region of the ablation zone (Tc), at equal distances to the ablation electrode (d = 8 mm). Maximum temperature within the perfused zone was significantly lowered with Tv ranging from 54.1 ± 1.5 °C (20 ml/min) to 56.9 ± 1.5 °C (0.25 ml/min), compared to Tc from 63.2 ± 3.5 °C (20 ml/min) to 63.2 ± 2.6 °C (0.25 ml/min) (10 W group). The cross-sectional ablation zone area decreased with increasing flow rates from 184 ± 12 mm2 (0 ml/min) to 141 ± 20 mm2 (20 ml/min) at 10 W, and from 207 ± 22 mm2 (0 ml/min) to 158 ± 31 mm2 (20 ml/min) in the 25 W group. Significant heat sink effects were observed under thyroid-specific conditions even at flow rates ≤ 1 ml/min. In thyroid nodules with prominent vasculature, heat dissipation through perfusion may therefore result in clinically relevant limitations to ablation efficacy.
Addition of fibers derived from paper mill sludge in paper coatings: impact on microstructure, surface and optical properties
Authors: Altay Bilge Nazli , Aksoy Burak , Huq Anamika , Hailstone Richard , Klass Charles P. , Demir Muslum , Williams Scott 
Published: November 2023

AbstractTraditionally, cellulose nanofiber (CNF) production has primarily relied on virgin cellulose sources. Yet, the shift to using paper mill sludge (PMS) as a source for CNF underscores the significance of reusing and recycling industrial byproducts. PMS contains significant amounts of cellulose that can be extracted as a raw material. The purpose of present study is to provide a sustainable approach to PMS utilization as a paper coating additive in the cellulose nanofibrils (CNFPMS) form via simply scalable wire-wound rod coating method. The effect of CNFPMS additive amounts at two coating layers on microstructure and surface properties of coatings such as porosity, air permeability surface roughness and optical properties such as brightness, gloss and CIE L*a*b* is studied, which they can also provide insight for the eventual print performance. Results indicated that the obtained CNFPMS in paper coating shows 52% decrease in porosity, presenting significant improvement in the coating microstructure. The marginal increase in permeability coefficient and surface roughness, 54% and 10%, respectively, suggests improving color reproduction and preventing color density losses. Optical analysis showed slight decrease in brightness and gloss, as was expected. Notably, the lightness was improved, which also indicates increasing color gamut volume in printing applications. As a result, the current work offers a sustainable approach to manage PMS for use in paper coatings as a high-value-added material.
Surface settlement law of double-hole pipe-jacking tunnel undercrossing expressway
Authors: Deng Meilong , Ding Fei , Liu Yang , Huang Xin , He Yu , Zhao Jinpeng 
Published: November 2023

AbstractWith the rapid urbanization process in China, there has been a significant development of urban underground spaces. The pipe-jacking method has gained popularity in various projects due to its advantages such as short construction period, adaptability to different soil conditions, and minimal excavation disturbance. This study focuses on a tunnel project involving double-hole rectangular pipe-jacking under an expressway. Utilizing FLAC software, a three-dimensional numerical model was created to analyze the impact of double-hole pipe-jacking construction on surface settlement and deformation of the expressway. The simulation results were validated by comparing them with field monitoring data. The study also investigated the impact of different construction parameters, such as excavation sequence and the angle of underpassing the expressway, on surface settlement. Additionally, the surface settlement curve at the slope bottom of the expressway exhibits asymmetric distribution and an offset center in the settlement trough. It is recommended to carry out the construction of double-hole pipe-jacking in the sequence of "big first and then small". Furthermore, when the included angle between the expressway and the jacking axis is 90°, the impact on surface settlement is minimized. This research provides valuable insights for the construction of double-hole pipe-jacking underpass structures in tunnel engineering.
Robot occupations affect the categorization border between human and robot faces
Authors: Shen Junyi , Tang Guyue , Koyama Shinichi 
Published: November 2023

AbstractThe Uncanny Valley hypothesis implies that people perceive a subjective border between human and robot faces. The robot–human border refers to the level of human-like features that distinguishes humans from robots. However, whether people’s perceived anthropomorphism and robot–human borders are consistent across different robot occupations remains to be explored. This study examined the robot–human border by analyzing the human photo proportion represented by the point of subjective equality in three image classification tasks. Stimulus images were generated by morphing a robot face photo and one each of four human photos in systematically changed proportions. Participants classified these morphed images in three different robot occupational conditions to explore the effect of changing robot jobs on the robot–human border. The results indicated that robot occupation and participant age and gender influenced people’s perceived anthropomorphism of robots. These can be explained by the implicit link between robot job and appearance, especially in a stereotyped context. The study suggests that giving an expected appearance to a robot may reproduce and strengthen a stereotype that associates a certain appearance with a certain job.
Analysis of drilling vibration characteristics of anchoring system in coal mine
Authors: Xie Miao , Li Yuqi , Zhang Hongyu , Yang Zhiyong , Ren Ze , Nie Rendong 
Published: November 2023

AbstractA new type of parallel operation unit for excavating and supporting anchors is proposed to address the issue of imbalanced excavation anchor ratio in coal mines. By equipping a straddle type anchoring drilling rig group, the synchronous parallel and fast operation mode for excavating and supporting anchors is achieved; Consider the problem of poor drilling stability of drill pipes in coal mines due to the coupling vibration between surrounding rock and anchoring equipment. Firstly, taking the multi drilling rig anchoring system as the research object, considering the influence of the equipment itself as an influencing factor on the vibration of the drill pipe, a dynamic model of the system is constructed using Lagrangian equations, and analytical solutions for the vibration displacement of each mass block are obtained; In order to more intuitively represent the vibration process of the drill pipe, Ansys is used to conduct modal analysis on the key components of the anchoring drilling rig system, and obtain the natural frequencies and vibration modes of each order of the key components; Using Adams to solve the rigid flexible coupling dynamic model of the anchoring drilling rig system, the vibration response laws of the drill pipe under different operating states were obtained. Secondly, Abaqus was used to simulate the drilling process of the drill pipe and obtain the vibration response law generated by the interaction between the drill pipe and the surrounding rock; The results indicate that the anchoring equipment has a greater impact on the vibration of the drill pipe, and the surrounding rock has a more stable impact on the vibration of the drill pipe. Due to the short body and large span structure of the anchoring system crossbeam expansion frame, the vibration response of the drill pipe is significantly greater than that of the retracted state of the drilling rig due to being in an unstable cantilever state when the drilling rig is extended. The theoretical reliability of the vibration response law of the drill pipe under different states has been further verified through drilling experiments of the anchoring system prototype. The relevant theories can provide a theoretical basis for the implementation of automatic anchoring technology in the anchoring system.
Cube-shaped Cobalt-doped zinc oxide nanoparticles with increased visible-light-driven photocatalytic activity achieved by green co-precipitation synthesis
Authors: Meky Asmaa I. , Hassaan Mohamed A. , Fetouh Howida A. , Ismail Amel M. , El Nemr Ahmed 
Published: November 2023

AbstractFrom the perspective of environmental protection, the highly efficient degradation of antibiotics and organic dyes in wastewater needs to be tackled as soon as possible. In this study, an ecofriendly and green cube-shaped cobalt-doped zinc oxide nanoparticles (Co–ZnO NPs) photocatalyst using Pterocladia Capillacea (P. Capillacea) water extract loaded with 5, 10, and 15% cobalt ions were formed via co-precipitation process to degrade antibiotics. The prepared Co–ZnO NPs were tested as a photocatalyst for the photodegradation of ciprofloxacin (CIPF) in the presence of a visible LED-light source. Co–ZnO NPs have been obtained through the co-precipitation method in the presence of P. Capillacea extract as a green capping agent and reducing agent, for the first time. Several characterization techniques including FTIR, XRD, BET, XPS, TEM, EDX, SEM, TGA and DRS UV–Vis spectroscopy were applied to study the prepared Co–ZnO NPs. XRD results suggested that the average size of these NPs ranged between 42.82 and 46.02 nm with a hexagonal wurtzite structure. Tauc plot shows that the optical energy bandgap of ZnO NPs (3.19 eV) gradually decreases to 2.92 eV by Co doping. Examinations showed that 5% Co–ZnO NPs was the highest efficient catalyst for the CIPF photodegradation when compared with ZnO NPs and other 10 and 15% Co–ZnO NPs. A 10 mg/L solution of CIPF was photo-degraded (100%) within the first 15 min irradiation. The kinetics showed that the first-order model is suitable for displaying the rate of reaction and amount of CIPF elimination with R2 = 0.952. Moreover, central composite design optimization of the 5% Co-doped ZnO NPs was also investigated.
Effects of comorbid chronic kidney disease on mortality in idiopathic pulmonary fibrosis patients and influence of pirfenidone
Authors: Jo Yong Suk , Kim Kyung Joo , Rhee Chin Kook , Kim Yong Hyun 
Published: November 2023

AbstractChronic kidney disease (CKD) is a comorbidity in idiopathic pulmonary fibrosis (IPF), and managing IPF with CKD is challenging due to limited options for antifibrotic therapy. The aim of this study was to examine the prevalence of CKD and prescription status of pirfenidone in IPF patients and to analyze its impact on mortality. Data from the Korean National Health Insurance Service (NHIS) database between October 2015 and September 2021 were used. IPF and CKD were defined based on both International Classification of Diseases 10th Revision (ICD-10) codes and Rare Intractable Disease (RID) codes. The risk of mortality was assessed based on accompanying CKD with or without antifibrotic therapy. Among 5038 patients with IPF, 8.4% had comorbid CKD and 83.3% with CKD did not receive renal replacement therapy (RRT). Patients with IPF and CKD were older, predominantly male, and had more frequent comorbidities such as cardiovascular disease and diabetes mellitus than subjects without CKD. Pirfenidone was prescribed to 105 (24.6%) of 426 CKD patients, and 89.5% of them did not receive RRT. Pirfenidone was also prescribed to 775 (16.8%) of 4612 IPF patients without CKD. Significant difference was not found in all-cause mortality between the IPF patients with or without CKD regardless of pirfenidone treatment. The use of antifibrotics in IPF patients with CKD is limited due to CKD severity; however, evidence is lacking. Mortality did not increase with accompanying CKD regardless of antifibrotic use. Further research on IPF and CKD is needed.
Sustainable extraction of bioactive compound from apple pomace through lactic acid bacteria (LAB) fermentation
Authors: Kalinowska Monika , Gołebiewska Ewelina , Zawadzka Małgorzata , Choińska Renata , Koronkiewicz Kamila , Piasecka-Jóźwiak Katarzyna , Bujak Marzena 
Published: November 2023

AbstractApple pomace (AP), a by-product of the juice industry, is a rich and inexpensive source of natural bioactive substances, including phenolic compounds, that exhibit health–promoting effects. The recovery of these compounds from plant material using only classical extraction techniques and environmentally friendly solvents is often ineffective due to the entrapment of some compounds in the complex structures of plant cell walls. Lactic Acid Bacteria (LAB) fermentation can be a simple technology to increase the content of phenolic compounds, as well as the antioxidant activity of plant material. In this study, pomace from conventionally grown apples (Malus Domestica) of the Ligol cultivar were fermented with selected LAB strains (Lpb. plantarum KKP 3182, Lpb. plantarum KKP 1527, Lpb. plantarum ZFB 200), commercial starter cultures of Lpb. plantarum, and spontaneously. The fermented material was then subjected to ultrasound-assisted extraction, and the resulting extracts were analysed for their composition (phenolic compounds, triterpenoids, simple organic acids), and antioxidant activity. We found that: (1) the total phenolic content of AP extracts fermented with Lpb. plantarum KKP 1527 was about 30% higher than that of non-fermented AP extracts, (2) extracts of AP fermented with Lpb. plantarum KKP 1527 characterized a higher value of the antioxidant activity, (3) an increase in gallic acid procyanidin A2, protocatechuic acid, and procyanidin B2, while a decrease in rutin and quercetin was observed. The results indicated that AP fermented with Lpb. plantarum KKP 1527 may be a powerful and low–cost source of natural antioxidants which have applications in many industries.
Assessment of retinal and choroidal microcirculation after unilateral recession–resection surgery for horizontal strabismus by swept-source optical coherence tomography angiography
Authors: Meng Yang , Xu Yishuang , Xiao Di , Chen Changzheng , Hua Dihao , Xu Yonghong 
Published: November 2023

AbstractThis study explored the possible hemodynamic changes of the retina and choroid after horizontal strabismus surgery using swept-source optical coherence tomography angiography (SS-OCTA). 32 eyes of 32 patients who underwent unilateral horizontal rectus muscle recession–resection surgery were included. SS-OCTA examinations were performed preoperatively and one week postoperatively. Several OCTA measurements were used, including vessel density (VD) of the superficial vascular complex (SVC), VD of the deep vascular complex (DVC), VD of the choriocapillaris (CC), choroidal vascular index (CVI) and choroidal thickness (CT). No significant change in VD of SVC, DVC, and CC was observed whereas CT increased significantly with CVI unchanged. Recession–resection surgery for horizontal strabismus seemed not to significantly influence the microcirculation of the retina and CC in the early postoperative period. However, choroidal thickening happened with a constant CVI probably due to the postoperative inflammation. Further studies are needed to investigate the long-term effects of unilateral recession–resection surgery for horizontal strabismus on the microcirculation of the retina and choroid.
Perception, experience and resilience to risks: a global analysis
Authors: Kieu Minh , Senanayake Gayani 
Published: November 2023

AbstractIndividual resilience is crucial amid rising global threats, yet risk perceptions and resilience worldwide remain inadequately elucidated. This research pioneers a global-scale analysis of individual risk perspectives and perceived resilience capacities. Leveraging survey data encompassing over 120 countries, we develop novel indices quantifying subjective risk perceptions, experiences, impacts, and resilience across diverse populations. Causal analysis techniques shed light on the complex dynamics shaping individual confidence in their resilience. We unveil vast disparities in risk impacts arising from differential adaptation rates. Income perception emerges as an outsized driver of resilience globally, though its influence varies contextually. Ultimately, this study challenges universal narratives of homogeneous risk experiences and perceived resilience worldwide. The globally-representative indices and causal insights provide vital evidence to inform context-specific, demographically-attuned interventions for strengthening resilience equitably. This research underscores the urgent need for inclusive policies tailored to localised risk landscapes.
UV-C irradiation as an effective tool for sterilization of porcine chimeric VP1-PCV2bCap recombinant vaccine
Authors: Vrablikova Alena , Fojtikova Martina , Hezova Renata , Simeckova Pavlina , Brezani Veronika , Strakova Nicol , Fraiberk Martin , Kotoucek Jan , Masek Josef , Psikal Ivan 
Published: November 2023

AbstractUltraviolet irradiation is an effective method of virus and bacteria inactivation. The dose of UV-C light necessary for baculovirus inactivation by measurement of fluorescent GFP protein produced by baculovirus expression system after the irradiation of baculovirus culture in doses ranging from 3.5 to 42 J/m2 was determined. At a dose of 36.8 J/m2, only 0.5% of GFP-expressing cells were detected by flow cytometry and confocal microscopy. The stability of purified VP1-PCV2bCap protein produced by baculovirus expression system was analyzed after the irradiation at doses ranging from 3.5 to 19.3 J/m2. Up to the dose of 11 J/m2, no significant effect of UV-C light on the stability of VP1-PCV2bCap was detected. We observed a dose-dependent increase in VP1-PCV2bCap-specific immune response in BALB/c mice immunized by recombinant protein sterilized by irradiation in dose 11 J/m2 with no significant difference between vaccines sterilized by UV-C light and filtration. A substantial difference in the production of VP1-PCV2bCap specific IgG was observed in piglets immunized with VP1-PCV2bCap sterilized by UV-C in comparison with protein sterilized by filtration in combination with the inactivation of baculovirus by binary ethylenimine. UV-C irradiation represents an effective method for vaccine sterilization, where commonly used methods of sterilization are not possible.
Prevalence and transmission risk of colistin and multidrug resistance in long-distance coastal aquaculture
Authors: An Taicheng , Cai Yiwei , Li Guiying , Li Shaoting , Wong Po Keung , Guo Jianhua , Zhao Huijun 
Published: November 2023

Abstract
Due to the wide use of antibiotics, intensive aquaculture farms have been recognized as a significant reservoir of antibiotic resistomes. Although the prevalence of colistin resistance genes and multidrug-resistant bacteria (MDRB) has been documented, empirical evidence for the transmission of colistin and multidrug resistance between bacterial communities in aquaculture farms through horizontal gene transfer (HGT) is lacking. Here, we report the prevalence and transmission risk of colistin and multidrug resistance in 27 aquaculture water samples from 9 aquaculture zones from over 5000 km of subtropical coastlines in southern China. The colistin resistance gene mcr−1, mobile genetic element (MGE) intl1 and 13 typical antibiotic resistance genes (ARGs) were prevalent in all the aquaculture water samples. Most types of antibiotic (especially colistin) resistance are transmissible in bacterial communities based on evidence from laboratory conjugation and transformation experiments. Diverse MDRB were detected in most of the aquaculture water samples, and a strain with high-level colistin resistance, named Ralstonia pickettii MCR, was isolated. The risk of horizontal transfer of the colistin resistance of R. pickettii MCR through conjugation and transformation was low, but the colistin resistance could be steadily transmitted to offspring through vertical transfer. The findings have important implications for the future regulation of antibiotic use in aquaculture farms globally to address the growing threat posed by antibiotic resistance to human health.