bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prospective analysis of sleep characteristics, chronotype, and risk of breast cancer in the california teachers study
Authors: Von Behren Julie , Goldberg Debbie , Hurley Susan , Clague DeHart Jessica , Wang Sophia S. , Reynolds Peggy 
Published: November 2023

Abstract
Purpose
Poor sleep quality and evening chronotype were associated with increased risk of breast cancer in a previous retrospective study in the California Teachers Study (CTS). The present analysis examines these sleep factors prospectively in the same cohort of women.

Methods
From the CTS, we included 1,085 incident breast cancer cases and 38,470 cancer-free participants from 2012 through 2019. We calculated time at risk and used Cox proportional hazards regression models to estimate the hazard ratios (HRs) and control for risk factors such as age, race, body mass index, family history of breast cancer, and reproductive history. The sleep factors examined were quality, latency, duration, disturbance, and sleep medication use, based on a shortened version of the Pittsburgh Sleep Quality Index, as well as chronotype (preference for morning or evening activity). This analysis was limited to women who were post-menopausal at the time they answered these sleep-related questions.

Results
Measures of sleep quality did not appear to be associated with subsequent breast cancer risk. The HR for evening chronotypes compared to morning chronotypes was somewhat elevated (HR 1.19, 95% CI 1.04, 1.36).

Conclusion
While the measures of sleep quality and duration were not associated with post-menopausal breast cancer risk in this prospective analysis, the modestly elevated risk observed for evening chronotypes was consistent with the prior retrospective analysis.
Localize surface plasmon resonance of silver nanoparticles using Mie theory
Authors: Alzoubi F. Y. , Ahmad Ahmad A. , Aljarrah Ihsan A. , Migdadi A. B. , Al-Bataineh Qais M. 
Published: November 2023

AbstractIn this work, the optical properties of silver nanoparticles (AgNPs) were explored using Mie theory compared with the experimental AgNPs using the chemical reduction method. Mie’s theory is suited for accurately evaluating the scattering, absorption, and extinction cross-sections of spherical AgNPs. Therefore, the wavelength of localized surface plasmon resonance (LSPR) in the optical spectra of the spherical AgNPs was calculated. The experimental AgNPs have a spherical shape with an average particle size of 30 nm. In addition, the crystalline structure of AgNPs was found to be cubic with fcc structure with lattice constant $$a=$$

a
=

4.155 Å. Moreover, the excitation of the LSPR of the AgNPs was simulated using the finite-difference time-domain (FDTD) method at different wavelengths to explore the LSPR phenomena. The results show that spherical AgNPs are the most widely used materials in biosensors, biomedicine, optoelectronic devices, and solar cells due to their surface plasmon resonances in the visible spectrum region.
A novel self-gripping long-term resorbable mesh providing temporary support for open primary ventral and incisional hernia
Authors: Vestberg Robert , Lecuivre Julie , Radlovic Amandine , Payet Emilie , Bayon Yves , Bouré Ludovic 
Published: November 2023

AbstractA novel synthetic fully long-term resorbable self-gripping mesh has been recently developed to reinforce soft tissue where weakness exists during ventral hernia repair open procedures. This resorbable mesh is a macroporous, knitted, poly-L-lactide, poly-trimethylene carbonate copolymer monofilament mesh with the ProGrip™ technology, providing grips on one side of the mesh. A new poly-L-lactide, poly-trimethylene copolymer was developed to provide the required features for mechanical support during at least 20 weeks covering the critical healing period, including resistance to fatigue under cyclic loading conditions, as it occurs in patients. The yarns and mesh initial physical and biomechanical properties were characterized. Then, the mesh mechanical strength was evaluated over time. The mechanical properties of the proposed mesh were found to be above the generally recognized threshold value to mechanically support the repair site of a hernia over a 20-week period during in-vitro cyclic loading test. The mesh performance was evaluated in vivo using a published preclinical porcine model of hernia repair at 4-, 12- and 20-weeks post implantation. The burst strength of the hernia repair sites reinforced with the new mesh were higher at 4 & 12 weeks and comparable at 20 weeks to the one of the native abdominal walls. At all time points, the mesh was well tolerated with moderate inflammation and was fast integrated in the abdominal wall at 4 weeks. Particularly, the grips were nicely engulfed in the newly formed connective tissue. They must facilitate the anchoring of the mesh by their extension from the mesh and their mushroom shape. The preclinical data of the self-gripping resorbable mesh suggests that it has all the favorable characteristics for future clinical use during ventral hernia repair open procedures.
Graphical Abstract
Growth mindset as a protective factor for middle schoolers at academic risk
Authors: Younger Jessica Wise , D’Esposito Zoe , Geng Irene S. , Haft Stephanie L. ,   Project iLEAD Consortium, O’Laughlin Kristine D. , Anguera Joaquin A. , Bunge Silvia A. , Ferrer Emilio E. , Hoeft Fumiko , McCandliss Bruce D. , Mishra Jyoti , Rosenberg-Lee Miriam , Gazzaley Adam , Uncapher Melina R. 
Published: November 2023

AbstractGrowth mindset has been shown to predict academic achievement in a variety of student populations, though the strength of the relationship can vary depending on the characteristics of the students examined. Using a large-scale sample of middle school students from a diverse district in the United States, we examine how multiple facets of students’ experiences and background characteristics may interact to impact the relation between mindset and academic achievement. We consider whether the risk factors of socioeconomic status (including a student’s daily experience of that status) and recent school transition interacted with mindset in predicting academic achievement. We show that mindset is most predictive of academic achievement in students with two academic risk factors. These results highlight the importance of context when considering how mindset might be used to improve academic achievement for students at the greatest academic risk.
Potentially toxic elements in different tissues of great cormorant (Phalacrocorax carbo) at a wetland area
Authors: Lehel József , Grúz Adrienn , Bartha András , Menyhárt László , Szabó Rita , Tibor Kocsner , Budai Péter 
Published: November 2023

AbstractConcentrations of 4 potentially toxic elements (As, Cd, Hg, Pb) were investigated in the feather, liver, kidney, and bone of great cormorants (Phalacrocorax carbo). The tissue samples were taken at the Central Tisza - Jászság Nature Conservation Area in Hungary. They were analysed by inductively coupled plasma optical emission spectroscopy (ICP-OES). The goal of the investigation was to analyse the metal burden of the above-mentioned elements in the various tissues of these wild birds and to provide important information for monitoring the environmental pollution.Amongst the examined potentially toxic elements no statistical gender difference was observed, so the data were not separated based on them during the statistical analysis. The concentration of mercury was the highest in the feather, followed by the liver, kidney, and bone. The lead was detected in the feather with the highest level followed by the kidney, liver, and bone. The cadmium was determined in all investigated tissues with the next descending order: kidney > bone > liver > feather. Highest arsenic concentration was measured in the feather, followed by liver, kidney, and bone with the same concentration.The detected concentrations of the investigated potentially toxic elements in different tissues of great cormorants (feathers, liver, kidney, bone) means that the living area of this birds is not highly contaminated to induce health problems or toxic signs, or even other undesirable effect in the animals.
Unpacking the complexities of crisis innovation: a comprehensive review of ecosystem-level responses to exogenous shocks
Authors: Brem Alexander , Nylund Petra A. , Roshani Saeed 
Published: November 2023

AbstractInnovation in times of crisis has experienced a flood of research in the wake of recent events. These studies are dispersed over a broad range of fields and do not adequately reflect earlier research or prior crises. To encourage the convergence of related literature streams, we define crisis innovation as an ecosystem-level process to meet the needs of—and overcome the resource constraints derived from—an exogenous shock. We then conduct a systematic literature review aided by machine learning techniques, specifically utilizing topic modeling. We derive a taxonomy of crisis innovation, which represents innovation as a response to societal crisis, funding crisis, financial crisis, economic crisis, digitalization, transformation, political crisis, strategy crisis, and organizational crisis. We find that crisis innovation drives digitalization through increased motivation for open and ecosystem innovation, but also that the dynamic network structures required for lasting digital transformation are often not implemented during crisis.
Teaching for statistical and data literacy in K-12 STEM education: a systematic review on teacher variables, teacher education, and impacts on classroom practice
Authors: Schreiter Saskia , Friedrich Anja , Fuhr Hannah , Malone Sarah , Brünken Roland , Kuhn Jochen , Vogel Markus 
Published: November 2023

AbstractStatistical and data literacy have emerged as key competencies in the 21st-century. Science, technology, engineering, and mathematics (STEM) curricula have been adapted in various countries to place increased emphasis on proficient data use and statistical comprehension. Consequently, there is a need for an adequate education and professional training of STEM teachers. This systematic review analyzes and synthesizes research on teachers’ statistical and data literacy in K-12 STEM education. A total of 42 articles were analyzed, with a specific focus on teacher variables, teacher education, and their impact on classroom practice. The findings emphasize the recent emergence of research in this domain, particularly focusing on statistical literacy, with mathematics being the dominant STEM domain explored. Most studies examined cognitive variables of both pre-service and in-service teachers, revealing relevant gaps in knowledge and skills related to statistical and data literacy. Limited attention was given to teachers’ affective variables. Research on the complex relationships between teacher variables, their teaching practices, and their students’ learning is scarce, necessitating further investigation. Several pedagogical approaches to prepare STEM teachers for promoting statistical and data literacy in their classrooms were identified. Positive impacts on teachers’ cognitive and affective variables were observed, but longitudinal effects and transfer to classroom practice require further inquiry. As curricula worldwide increasingly emphasize statistical and data literacy, this review underscores the necessity of enhancing teachers' competencies, advocates for tailored pedagogical approaches, and emphasizes the need for further research to shape effective instruction in K-12 STEM education.
A Clinician’s Guide to the Changing Aortic Stenosis Landscape: Updates in Aortic Stenosis Diagnosis, Surveillance and Management
Authors: Meredith Thomas , Roy David , Muller David , Namasivayam Mayooran 
Published: November 2023

Abstract
Purpose of review
This review aims to update healthcare providers on contemporary diagnostic and treatment information pertaining to aortic stenosis.

Recent findings
The prevalence of aortic stenosis continues to increase, and so does the burden of treatable disease. This has important implications for healthcare systems and the economy. Accurate classification of aortic stenosis severity and determining optimal treatment timing remains a prime challenge to treating physicians. Furthermore, the drastic uptake of transcatheter aortic valve replacement has generated novel issues pertaining to younger patients whose post-intervention survival now exceeds device durability.

Summary
The keys to optimizing patient outcomes are delivering accuracy in disease classification, treatment selection and timing and procedural planning.
P2X7 Receptor: an Emerging Target in Alzheimer’s Disease
Authors: Huang Qiang , Ying Jun , Yu Wen , Dong Yao , Xiong Hao , Zhang Yiping , Liu Jie , Wang Xifeng , Hua Fuzhou 
Published: November 2023

AbstractAlzheimer’s disease (AD) is a major cause of age-related dementia, which is becoming a global health crisis. However, the pathogenesis and etiology of AD are still not fully understood. And there are no valid treatment methods or precise diagnostic tools for AD. There is increasing evidence that P2X7R expression is upregulated in AD and is involved in multiple related pathological processes such as Aβ plaques, neurogenic fiber tangles, oxidative stress, and chronic neuroinflammation. This suggests that P2X7R may be a key player in the development of AD. P2X7R is a member of the ligand-gated purinergic receptor (P2X) family. It has received attention in neuroscience due to its role in a wide range of aging and age-related neurological disorders. In this review, we summarize current information on the roles of P2X7R in AD and suggest potential pharmacological interventions to slow down AD progression.
Corpses, diehards and clubs: Ultras and organized crime in Italy
Authors: Scalia Vincenzo 
Published: November 2023

AbstractThis work will be dealing with the relation between football and organized crime in Italy. It will attempt to critically analyse the relations between football and organized crime. Its focus will be on the relation between ultras, that is a relevant part of organized supporters, and organized crime. The paper devotes particular attention to a 2017 Report of the Italian Parliamentary Anti-Mafia Commission which deals with the relationship between football and mafia. The analysis of the Anti-mafia Committee Report will help the purpose of de-constructing the assumptions that, firstly, there exists an organic alliance between ultras and organized crime, and, secondly, that this connection provides the ground for an infiltration of football as a business “from below”. Deconstruction will work by analysing the most relevant cases outlined by the Report of the Committee and relating them with the main theories of organised crime. It will thus become evident that there is no such thing as an organic alliance between criminal organisations and the ultras. Moreover, it will be evident that there is not a uniform pattern, but, rather, a difference between various local situations, according to the context.
The threat of ransomware in the food supply chain: a challenge for food defence
Authors: Manning Louise , Kowalska Aleksandra 
Published: November 2023

AbstractIn the food industry, the level of awareness of the need for food defence strategies has accelerated in recent years, in particular, mitigating the threat of ransomware. During the Covid-19 pandemic there were a number of high-profile organised food defence attacks on the food industry using ransomware, leading to imperative questions over the extent of the sector’s vulnerability to cyber-attack. This paper explores food defence through the lens of contemporary ransomware attacks in order to frame the need for an effective ransomware defence strategy at organisational and industry level. Food defence strategies have historically focused on extortion and sabotage as threats, but often in terms of physical rather than cyber-related attacks. The globalisation, digitalisation and integration of food supply chains can increase the level of vulnerability to ransomware. Ransomware is an example of an organised food defence threat that can operationalise both extortion and sabotage, but the perpetrators are remote, non-visible and often anonymous. Organisations need to adopt an effective food defence strategy that reduces the risk of a ransomware attack and can enable targeted and swift action in the event an incident occurs. Further collaboration between government and the private sector is needed for the development of effective governance structures addressing the risk of ransomware attacks. The novelty of this article lies in analysing the issue of ransomware attacks from the perspective of the food sector and food defence strategy. This study is of potential interest to academics, policy makers and those working in the industry.
Feeling uncomfortable in your own skin: a qualitative study of problematic skin picking in Italian women
Authors: Montali Lorenzo , Garnieri Sara 
Published: November 2023

AbstractSkin picking disorder (SPD) is a body-focused repetitive behavior recently added to the DSM-V. It mainly affects women, with a prevalence ranging from 1.5 to 5.4%. Picking causes skin lesions that can lead to serious infections and permanent skin problems, usually on the face, scalp, arms, and legs. The behavior impairs quality of life and is associated with psychological distress and difficulties in managing emotions. The disorder causes social embarrassment, leading to avoidance and social withdrawal. As the literature on the perspectives of people with SPD is limited, our research aimed to analyze the meanings they attribute to the behavior and its consequences. A second aim was to explore how interacting with an online community can affect the management of the condition. Using a qualitative descriptive approach, we interviewed twenty-one Italian women (aged 18–50) who self-identified as having SPD and were recruited through an online forum dedicated to the disorder. Three themes framed our analysis: “A stick in the wheel of everyday life,” “Other people’s eyes make you realize what you are doing is wrong,” and “The struggling search for control.” These themes highlight the impact of SPD on different areas of life, the difficulties in accessing competent healthcare providers, the stigma experienced by participants, and the usefulness of the online group on an informative, emotional, and social level. A better understanding of these patients’ perspectives can be useful for those providing professional care and those planning services for them in a Health Co-Inquiry approach that values patients’ activation.
Caregivers of ALS Patients: Their Experiences and Needs
Authors: Yang Kun , Xue Hongxia , Li Li , Tang Shan 
Published: November 2023

AbstractWe explored the care experiences and needs of the home caregivers of patients with amyotrophic lateral sclerosis (ALS) to improve their quality of life. We interviewed home caregivers in-depth and analyzed the data using Colaizzi's descriptive phenomenological method. We interviewed 11 home caregivers of patients with ALS with a disease duration between 1.5 and 4 years. Primary caregivers were predominantly female and were the patients' spouses. Daily caregiving time averaged 4–14 h for 0.5–3.5 years. Interview themes included helplessness and adaptation to life changes, hopelessness, compassion for the patient’s prognosis, and expectation for diverse support. The study sample size was limited, as all participants were from a single tertiary hospital, and all patients had severe functional impairment. Caregivers of patients with ALS experience a considerable burden. Patients and their caregivers can benefit from diversified support channels, and assistive communication systems can be applied to home care. Future research will focus on in-home public long-term care services in China.
Bending behavior of structured steel sheets with undercuts for interlocking with Al die-cast metal
Authors: Ringel Aron , Hirt Gerhard 
Published: November 2023

AbstractDue to the current changes in mobility, lightweight design concepts continue to be of particular interest to the automotive industry. One form is the multi-material design, in which the advantageous properties of different materials are combined in one component. In this work, a component made of a steel sheet with stiffening structures of cast aluminum is considered. The joint is created by channel structures with undercuts on the surface of the steel sheet, into which the molten aluminum can flow. After solidification, an interlocking connection is created. The aim of this work is to investigate the influence of a bending operation on the surface structure before the die casting process. Numerical simulations and experimental validations were performed with different bending angles and radii as well as orientations between the channel structure and the punch. The results show that the undercuts on the outer radius are reduced by up to 75% by the bending operation, thus weakening the resulting joint. On the inner radius, the channel opening width narrows by up to 73% and can thus impede the filling with the melt.
Cultivar-dependent and drought-induced modulation of secondary metabolites, adaptative defense in Fagopyrum esculentum L
Authors: Oksana Sytar , Marek Kovar , Marian Brestic , Marek Zivcak 
Published: November 2023

AbstractThe present study investigates the biochemical responses of buckwheat to drought stress, particularly focusing on phenolic acids and flavonoids, abundant in this crop. We hypothesize that distinct genotypic responses to drought stress will lead to variations in phenolic acid accumulation. Two common buckwheat cultivars, Panda (East European origin) and PI 482597 (originating from Zimbabwe), were subjected to drought treatment, with biochemical traits, relative water content, and photosynthetic pigments regularly assessed. While chlorophyll content remained unaffected by dehydration, total carotenoid content decreased. The unique increase in the chlorophyll to carotenoid ratio suggests a specific role of carotenoids in buckwheat's metabolic stress response. While most phenolic acids and flavonoids exhibited increasing trends during progressive dehydration, their dynamics differed. Notably, rutin content increased early in drought stress, while chlorogenic acid and kaempferol showed enhanced levels only under severe dehydration. Genotypic differences were observed in chlorogenic acid, neochlorogenic acid, cryptochlorogenic acid, 4-hydroxybenzoic acid, and quercetin. Conversely, trans-p-coumaric acid, trans-ferulic acid, vanillic acid, rutin, and kaempferol showed similar trends in both cultivars. By aligning observed drought-induced changes in phenolic compound contents with biosynthesis pathways, trade-offs between individual compounds were identified, contributing to the mechanistic understanding of varied stress responses.