bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diverse alleles of Photoperiod-H1 directly and indirectly affect barley yield-related traits under contrasting photoperiods and PHYTOCHROME C backgrounds
Authors: Parrado Jorge D , Slafer Gustavo A , Savin Roxana 
Published: January 2025

Abstract
Barley traits that determine grain number are established between jointing and flowering. The timing of flowering is critical for adaptation and yield as it affects the fertility of both the main shoot and tiller spikes. The Photoperiod-H1 (PPD-H1) gene controls flowering time and impacts spike fertility and yield in barley; however, it is not known if these effects are truly pleiotropic or indirect. Recent findings indicated that under extremely long photoperiods, barley near-isogenic lines (NILs) with contrasting PPD-H1 alleles tend to flower simultaneously, allowing any genetic effects to be determined independently of flowering time. We examined the direct impact of PPD-H1 on barley spike fertility and yield in two PHYC genetic backgrounds. Experiments combined (i) two NILs for PPD-H1 alleles (ppd-H1 or Ppd-H1) under two contrasting PHYTOCHROME C genetic backgrounds (PhyC-l and PhyC-e), and (ii) two photoperiod conditions (12 h and 24 h). Under a 24 h photoperiod, the PPD-H1 gene had a minimal impact on flowering time. The ppd-H1 allele increased grain number by enhancing spike fertility, irrespective of the PHYC background, through better resource allocation to juvenile spikes and more efficient production of fertile florets. These findings support a pleiotropic effect of ppd-H1 in determining flowering time and establishment of yield component traits.
Predicting the Galactic population of free-floating planets from realistic initial conditions
Authors: Coleman Gavin A L , DeRocco William 
Published: January 2025

ABSTRACT
We present the first prediction for the mass distribution function of Galactic free-floating planets (FFPs) that aims to accurately include the relative contributions of multiple formation pathways and stellar populations. We derive our predicted distribution from dedicated simulations of planet birth, growth, migration, and ejection around circumbinary systems and extend these results to also include the contributions from single and wide binary systems. Our resulting FFP mass distribution shows several distinct features, including a strong peak at ${\sim} 8\, {\rm M}_{\oplus }$ arising from the transition between pebble and gas accretion regimes and a trough at ${\sim} 1\, {\rm M}_{\oplus }$ due to the shift in the dominant ejection process from planet–planet scattering to ejection through interactions with stars in circumbinary systems. We find that interactions with the central binary in close circumbinary systems are likely the dominant progenitor for FFPs more massive than Earth, leading to a steep power-law dependence in mass that agrees well with existing observations. In contrast, we find planet–planet scattering events in single and wide binary systems likely produce the majority of planets at Mars mass and below, resulting in a shallower power-law dependence. Our results suggest that existing extrapolations into the sub-terrestrial mass range may significantly overestimate the true FFP abundance. The features we predict in the mass distribution of FFPs will be detectable by upcoming space-based microlensing surveys and, if observed, will provide key insight into the origins of FFPs and the environments in which they form.
On Schemas in Tonal Jazz Repertoire
Authors: Salley Keith 
Published: January 2025

Abstract
Jazz practice involves negotiating schemas at various levels, from general formal types (twelve-bar blues, rhythm changes, 32-bar ABAC) to individual chord symbols. This article discusses a number of common schemas at the sub-phrase level—harmonically associated but further characterized by rhythm, hypermeter, formal function, and sometimes melody—encountered in tonal jazz repertoire.
Phase II Trial of Brain MRI Surveillance in Stage IV Breast Cancer
Authors: Ahmed Kamran A , Kim Youngchul , Armaghani Avan J , Arrington John A , Costa Ricardo L , Czerniecki Brian J , Diaz Roberto , Dowell Robin A , Extermann Martine , Forsyth Peter A , Lee Kimberley T , Loftus Loretta , Mills Matthew N , Phuoc Vania H , Rosa Marilin , Soliman Hatem H , Sam Christine S , Washington Iman R , Soyano Aixa E , Han Hyo S 
Published: January 2025

Abstract

Background
Screening of asymptomatic stage IV breast cancer with brain MRIs is currently not recommended by National Comprehensive Cancer Network (NCCN) Guidelines. The incidence of asymptomatic brain metastasis is not well documented.

Methods
The study is designed as a single arm, phase II trial, with the goal of investigating surveillance brain MRIs in neurologically asymptomatic patients with metastatic breast cancer. Breast cancer patients were classified into triple negative (TN), HER2+, and hormone receptor (HR)+/HER2-. Patients underwent a surveillance brain MRI and a second brain MRI at 6 months if the baseline MRI was negative. Asymptomatic, stage IV breast cancer patients, ECOG ≤2, and life expectancy ≥6 months were eligible. The primary objective was to determine the frequency of asymptomatic brain metastasis in metastatic breast cancer. Clinical trial information: NCT05115474.

Results
A total of 101 patients completed the surveillance brain MRI including 40 HR+/HER2-, 33 HER2+, and 28 TN patients. The overall frequency of brain metastasis on initial surveillance brain MRI was 14% (n=14) with rates of 18%, 15%, and 10% in TN, HER2+, and HR+/HER2- patients, respectively. Following the 6-month MRI, the cumulative rates of brain metastasis increased to 25% in TN, 24% in HER2+, and 23% in HR+/HER2- patients.

Conclusions
The highest frequency of brain metastases at baseline was in TN and HER2+ breast cancer. Following the 6-month MRI, the cumulative frequency was approximately a quarter across all subtypes. These results warrant confirmatory trials to refine brain MRI surveillance recommendations for neurologically asymptomatic stage IV breast cancer.
BTZ Black Hole in the Nonextensive Generalizations of Gibbs Entropy
Authors: Bhattacharjee Amijit , Phukon Prabwal 
Published: January 2025

Abstract
We study the thermodynamics and thermodynamic geometry of the (2+1)D Banados–Teitelboim–Zanelli (BTZ) black hole within the framework of the nonextensive generalizations of Gibbs entropy. We investigate both the rotating (R-BTZ) and the charged (C-BTZ) BTZ black holes in these nonextensive entropy formalisms. We write down the Bekenstein–Hawking (BH) entropy of the black hole in terms of the nonextensive entropies, namely Kaniadakis entropy, Renyi entropy, and Barrow entropy. We investigate their impact on the thermodynamic phase structure and geometry of the BTZ black holes in both the ensembles, i.e. the fixed $(J)$ and fixed $(\Omega )$ ensembles for the R-BTZ black hole and the fixed $(Q)$ and fixed $(\Phi )$ ensembles for the C-BTZ black hole, where $J$, $\Omega$, $Q$, and $\Phi$ represent the angular momentum, angular velocity, charge, and the electric potential of the respective black holes. We investigate the Ruppeiner and geometrothermodynamic (GTD) geometries of the black hole for all the nonextensive entropy cases. We find that there are both Davies-type and Hawking–Page phase transitions in both the charged and rotating BTZ black holes for the Kaniadakis entropy case in all the above-mentioned thermodynamic ensembles. These phase transitions were not seen in the BH entropy case. We also find that the Ruppeiner and the GTD scalar for the Kaniadakis entropy show curvature singularities corresponding to Davies-type phase transitions in both the rotating and charged BTZ black holes.
How do corporate tax hikes affect investment allocation within multinationals?
Authors: De Vito Antonio , Jacob Martin , Schindler Dirk , Xu Guosong 
Published: January 2025

Abstract
This article studies how corporate tax hikes transmit across countries through multinationals’ internal networks of subsidiaries. We build a parsimonious multicountry model to highlight two opposing spillover effects: while tax competition between countries generates positive investment spillover, intra-firm production linkages predict negative spillover. Using subsidiary-level data and exogenous corporate tax hikes, we find that local business units cut investment by 0.5 percent for a 1 percent increase in foreign corporate tax. This result highlights the importance of production linkages in propagating foreign tax shocks, as the supply-chain-induced negative spillover dominates the positive spillover effect suggested by the conventional wisdom of tax competition.
The 2024 SSSP Presidential Address “Every Damn Day in America”: Racism and the Politics of Gun Violence
Authors: Bernstein Mary 
Published: January 2025

Abstract
This presidential address disrupts common misperceptions about what gun violence in the United States looks like, who is most affected, and how we should think about reducing the scourge of gun violence. I draw on seven years of ethnographic and interview-based research on gun violence prevention activism in Connecticut and nationally. Focusing on community gun violence and mass shootings, I demonstrate that structural racism and racist discourse distort what we know about gun violence, the experience of gun violence, and how we respond to and organize to reduce gun violence. Theoretically, I take a multi-institutional politics approach to understanding gun violence, examining how racist meaning systems as well as structural and institutional power shape discussions of gun violence. I conclude with a call for policy approaches that support intervention and prevention organizations, while simultaneously addressing the underlying causes of community gun violence that stem from the legacy of systemic racism: disenfranchisement, segregation, crumbling infrastructure, despair, warrior policing, lack of well-paying jobs and affordable housing, and lack of activities for youth.
Resolvin D2 restores monocyte anisocytosis and mediates a shift toward classical monocytes ex vivo in blood samples from patients after major burns
Authors: Nazemidashtarjandi Saeed , Supple Matthew D. , Yonker Lael M. , Sheridan Robert L. , Ryan Colleen M. , Karabacak Murat N. , Goverman Jeremy , Yarmush Martin L. , Irimia Daniel 
Published: January 2025

AbstractCirculating monocytes contribute to the defense against pathogens and play a crucial role in maintaining immune homeostasis. While there is substantial evidence regarding the triggers of monocyte activation, our understanding of how monocyte function is restored toward homeostasis after activation remains limited. Here, we assessed the changes in monocyte anisocytosis upon activation in blood, measured by monocyte distribution width (MDW), a biomarker for sepsis. We determined that the increase in MDW post‐lipopolysaccharide (LPS) stimulation in the blood can be reversed promptly by adding resolvin D2 (RvD2), and we measured a decrease in interleukin‐1 beta (IL‐1β) in blood, and a decrease in the size of the population of intermediate monocyte subsets. Moreover, the ex vivo addition of RvD2 to blood samples from burn patients with high MDW restored normal MDW values. Further studies are needed to probe the potential therapeutic role of RvD2 in the context of burn injuries.
Using the Experience of Novice Reviewers to Inform Journal Peer Reviewer Development
Authors: Gazza Elizabeth A. , Matthias April D. , Atkins Megan 
Published: January 2025

Abstract

AIM
The aim of this study was to uncover what it is like to be a novice peer reviewer for journals that publish articles that can influence nursing education and/or practice.

BACKGROUND
Comprehensive and effective approaches to reviewer development, based on reviewer experience, were not reported in the literature.

METHOD
The study followed a hermeneutic phenomenological approach. Data were collected via personal interviews and a demographic questionnaire.

RESULTS
Eleven novice reviewers, who had reviewed no more than five journal manuscripts, participated in the study. Thematic analysis uncovered five themes: sitting at the grown-up’s table, building and using the toolbox, putting in the human factor, assuming this is what you’re looking for, and appreciating the experience.

CONCLUSION
This study is the first to uncover the experience of being a novice journal peer reviewer. Findings can inform the creation of comprehensive development programs to support new and continuing journal peer reviewers.
Competency Development for E-Mentors of Undergraduate Nursing Students Using E-Delphi Method
Authors: Villarante Delwin Millan , Schuler Ethan , Rincon Teresa , O’Donoghue Sharon C. 
Published: January 2025

Background
The supply of future registered nurses successfully matriculating from undergraduate nursing programs is critical to address the national nursing shortage. Mentoring in higher education increases recruitment and retention within nursing programs. E-mentoring is an innovative approach to mentorship within nursing education that can optimize undergraduate nursing graduation rates. Establishing E-Mentor Competencies (EMCs) for nurses may ultimately address the nursing shortage gap.

Objectives
The purpose of this study is to develop EMCs for mentors of undergraduate nursing students through expert group consensus via e-Delphi methodology.

Methodology
The EMC survey was developed by a subject matter expert group and electronically distributed to an expert participant group. Items were ranked using a 5-point Likert scale for importance and relevance during iterative survey rounds to reach consensus.

Results
Sixteen EMCs were identified and categorized as knowledge, skill, or attitude. This research study identified 16 competencies required of an e-mentor for undergraduate nursing students. The 3 most important competencies identified were relationship building (4.71), cultural competence (4.88), and empathy and support (4.55).

Discussion
The EMCs identified by expert participant group consensus will provide a standard level of knowledge, skills, and attitudes for e-mentorship of undergraduate nursing students. Results may lead to an enhanced e-mentorship experience for both mentee and mentor and support existing and future e-mentor programs.
Health and Health Care Utilization Outcomes for Individuals With Traumatic Brain Injury: A 1-Year Longitudinal Study
Authors: Waltzman Dana , Miller Gabrielle F. , Xu Likang , Haarbauer-Krupa Juliet , Hammond Flora M. 
Published: January 2025

Objective: Traumatic brain injury (TBI) can result in new onset of comorbidities and limited studies suggest health care utilization following TBI may be high. Setting, Participants, Mean Measures, and Design: This study used 2018 and 2019 MarketScan Commercial Claims and Encounters data to examine differences in longitudinal health outcomes (health care utilization and new diagnoses) by various demographic factors (age, sex, U.S. region, intent/mechanism of injury, urbanicity, and insurance status) among individuals with and without a TBI in the year following an index health care encounter. Results: Results show that within 1 year of the initial encounter, a higher percentage of patients with TBI versus without TBI had at least one outpatient visit (96.7% vs 86.1%), emergency department (ED) visit (28.5% vs 13.1%), or hospital admission (6.4% vs 2.6%). Both children (33.8% vs 23.4%) and adults (43.8% vs 31.4%) who sustained a TBI had a higher percentage of new diagnoses within 1 year compared to the non-TBI group. Additionally, individuals with a TBI had greater health care utilization across all types of health care settings (outpatient and inpatient), visits (ED visits and hospital admissions), and across all demographic factors (P < .001). Conclusion: These results may inform future research around the development of systems of care to improve longer-term outcomes in individuals with TBI.
The Effect of Cataract Surgery on Stereoacuity, Balance, and Falls in Patients With Senile Cataract
Authors: Özer Ömer , Dursun Özer , Eroz Pınar , Guclu Emin Serbülent 
Published: January 2025

Objectives:
To investigate the effect of cataract surgery on visual acuity, stereoacuity, balance, and falls in patients with senile cataract.

Methods:
Prospective, cross-sectional study. The patients were divided into group 1 if the first surgery was performed on the dominant eye and group 2 on the nondominant eye. After a complete ophthalmologic examination, all patients underwent stereoacuity tests (Titmus and TNO test); Berg Balance Scale and the number of falls in the last 36 months were recorded. All assessments were performed at three time points: the preoperative period, 6 months after the first surgery (primary endpoint), and 24 months after the second surgery (secondary endpoint).

Results:
The mean number of falls was 4.95±2.6/year in the preoperative period and 1.43±0.59/year in the postoperative period. The incidence of falls after the second surgery decreased by 53.15% compared with the preoperative period. The number of falls and preoperative stereoacuity were negatively and moderately correlated (r=−0.546) (P=0.033). In univariate and multivariate analysis, only low preoperative corrected distance visual acuity in the dominant eye was associated with poor stereoacuity (P=0.001) and a high number of falls (P<0.001) in the preoperative period.

Conclusion:
Cataract surgery in patients with senile cataracts not only improves visual acuity but also increases stereoacuity level, improves balance, and decreases falls. These effects should be further studied in multicenter, large-participant studies.
Growth and Survival of a Cohort of Congenital Zika Virus Syndrome Children Born With Microcephaly and Children Who Developed With Microcephaly After Birth
Authors: Arrais Nivia M. R. , Maia Claudia R. S. , Jerômino Selma M. B. , Neri João I. C. F. , Melo Áurea N. , Bezerra Mylena T. A. L. , de Moraes-Pinto Maria Isabel 
Published: January 2025

Background and objectives:
Little is known about the clinical course of children born with congenital Zika virus syndrome (CZS). This article aimed to analyze the growth and survival of children with CZS born with microcephaly and children who developed with microcephaly after birth in the 36-month period.

Methods:
This is a cohort of children diagnosed with CZS who were monitored in a series of outpatient appointments, with clinical and demographic information and anthropometric measurements collected. The Mann-Kendall test evaluated the trend of the mean Z-score of head circumference (HC) for age and the Kaplan-Meier model described the time to low weight and short length according to the classification of HC at birth.

Results:
Children born without microcephaly had a reduction in HC growth velocity (P = 0.019) and took longer to reach low weight (P = 0.036) and short length (P = 0.034) when compared with those born with microcephaly. Seven (10%) deaths were reported, and the probability of survival after 36 months of age was 88%. In children with arthrogryposis, the risk of death was 7 times as high as in those without this condition (adjusted hazard ratio: 6.49; 95% confidence interval: 1.31–32.20; P = 0.022).

Conclusions:
In this cohort of children with CZS, 20% were born without microcephaly and all of them presented a reduction in HC growth velocity, which led to microcephaly. Progression to low weight and short length occurred in the first years of life, and that was faster in those born with microcephaly. Healthcare providers should be aware of these conditions that pose a risk of unfavorable anthropometric measurements and death.
Maternal-Newborn ABO Blood Group Congruence Among Consecutive Births and Risk of Serious Neonatal Infection: Retrospective Cohort Study
Authors: Ray Joel G. , Butler Emily Ana , Grandi Sonia M. , Cohen Eyal 
Published: January 2025

Background:
Differing ABO blood groups between a mother and her fetus may confer a lower risk of serious neonatal infection. How sensitization in the first pregnancy influences this phenomenon in a subsequent pregnancy is unclear. Accordingly, this study determined whether maternal-newborn ABO blood group incongruence in a first pregnancy further modifies the risk of serious infection in a subsequent pregnancy marked by ABO incongruency.

Methods:
This population-based retrospective cohort study used linked patient-level datasets in Ontario, Canada, from 2008 to 2022. Included were mothers with 2 consecutive live births, with recorded maternal and newborn ABO blood group data. The exposure considered both first- and second-born siblings’ ABO blood group congruency with their mother. The outcome was a serious neonatal infection within 27 days after birth. Logistic regression models generated adjusted odds ratios (aORs) and 95% confidence intervals (CIs), adjusted for gestational age at birth.

Results:
Included were 14,739 mother-infant triads. Relative to maternal-newborn congruency in the second pregnancy, incongruent ABO blood groups in the second pregnancy were associated with an aOR of 0.72 (95% CI, 0.53–0.97) for a serious neonatal infection arising in the second-born infant. However, if the first and second siblings each had incongruent ABO blood groups with their mother, the aOR of serious infection in the second-born infant was not significantly lower [0.74 (95% CI, 0.52–1.06)].

Conclusions:
Second-born infants whose ABO blood group was incongruent with that of their mother had a lower risk of serious neonatal infection. However, ABO incongruence from a prior birth did not modify that relation.
Early Predictive Value of Laboratory Inflammatory Markers in Evaluating Both Lung Involvement and Progression in Hospitalized Patients With COVID-19
Authors: Barzegari Atefeh , Kamyab Amirhossein , Halvani Abdolhasan , Poor Seyed Mostafa Baghaei 
Published: January 2025

Background
The new coronavirus known as SARS-CoV-2, first discovered in Wuhan, China, in December 2019, rapidly spread over the globe. It has created many challenges for the world's health and treatment systems. Due to the outspread of this virus and the limited treatment facilities, one of the important issues is the early diagnosis of patients who may continue to suffer from a severe type of disease. This study aims to determine the relationship between hospitalized COVID-19 patients' computed tomography (CT) scan results and laboratory results such as neutrophil-to-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR).

Methods
We created this retrospective study to investigate the relationship between the CT scan results of COVID-19 patients and laboratory results such as NLR and PLR ratios. We randomly sampled individuals whose hospitalization records from Shahada Kargar Hospital in Yazd in 2021 showed a positive COVID-19 test diagnosis.

Results
During this investigation, 17% of patients were hospitalized in the intensive care unit, and around 7% of patients passed away. These prognostic values have had a significant relationship with the mean NLR and (P = 0.004). In addition, this NLR laboratory index indicated a considerable positive correlation coefficient with the CT scan score (P = 0.014).

Conclusions
Our results reflect the significant predictive ability of NLR and PLR ratios regarding the prognosis of hospitalized patients with COVID-19. Imaging findings use the CT scan score as an indicator to predict the amount of NLR. In this way, the results of preliminary laboratory tests and imaging can determine the affected patient's progress to a large extent.