bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrative taxonomic analyses reveal first country records of Occidozyga shiwandashanensis Chen, Peng, Liu, Huang, Liao &amp; Mo, 2022 and Hylarana latouchii (Boulenger, 1899) (Anura, Dicroglossidae, Ranidae) from Vietnam
Authors: Tran Tung , Hoang Chung , Luong Anh , Nguyen Truong , Ziegler Thomas , Pham Cuong 
Published: October 2023

Occidozyga shiwandashaensis was recently discovered from Guangxi Province of China. Hylarana latouchii is a widespread species in southern China, including Hong Kong and Taiwan. Both species are expected to be found in the border areas between Vietnam and China; however, no records of these frogs have been documented from Vietnam so far.
We record two species of amphibians for the first time from Vietnam, namely Occidozyga shiwandashaensis from Bac Giang Province and Hylarana latouchii from Hai Phong City and Quang Ninh Province in northern Vietnam. Morphologically, the Vietnamese representatives of O. shiwandashanensis resemble the type series from China. The specimens of H. latouchii from Vietnam slightly differ from the type series from China by having a larger size (SVL 48.6–51.7 mm in males, SVL 58.4 mm in the females vs. 36.0–40.0 mm in males, 42.0–53.0 mm in females). Genetic distances between the Vietnamese records and the type specimens of O. shiwandashanensis from China varied from 0 to 1.5% (16S gene). Genetic divergences between the Vietnamese records and H. latouchii from the type locality were 2.0–2.6% (16S gene). In addition, morphological data and natural history notes of the aforementioned species are provided, based on the new records from Vietnam. ­­
Myocardial Perfusion Scan Study before and after On-Pump Coronary Artery Bypass Grafting Surgery – A Single-Center Study
Authors: Chellasamy Rajeev Thilak , Sai Chandran B V , Halanaik Dhanapathi , Rath Durga Prasad 
Published: October 2023

Aim:
Ischemic cardiac disease is the most common adult heart disease. The primary aim of the study was to analyze the myocardial perfusion status of the patients undergoing coronary artery bypass graft using sestamibi scan and assess the improvement in perfusion status of the myocardium after the surgery.

Materials and Methods:
This study was a descriptive study consisting of a single group of patients undergoing elective surgery for coronary artery disease. The patients underwent myocardial perfusion scan before surgery. Another myocardial perfusion scan was performed 3 months after the surgery. The change in myocardial perfusion status was analyzed.

Results:
Totally, 49 patients were initially included in this study. Seven patients lost their follow-up. Among the 17 patients who had severely reduced tracer uptake preoperatively, 3 (7.1%) had a good outcome, while 14 (33.3%) had a poor outcome, which was statistically significant (P < 0.001). Eighteen cases who belonged to the category of moderately reduced tracer uptake while analyzed, it was found that 16 (38.1%) had a good outcome while only 2 (4.8%) had a poor outcome; the difference in proportion among these two groups was statistically significant (P < 0.001). The patients who had mildly reduced tracer uptake preoperatively, all 3 (7.1%) had a good outcome, but it was not statistically significant (P = 0.23). Four patients had adequate tracer uptake preoperatively, out of which 3 (7.1%) had a good outcome, while the other 1 (2.4%) had a poor outcome and was not statistically significant (P = 0.63).

Conclusion:
Surgical revascularization improves perfusion in a selective group of patients.
‘Coming out’/self-disclosure in LGBTQ+ adolescents and youth: International and Indian scenario - A narrative review of published studies in the last decade (2012-2022)
Authors: Sahoo Swapnajeet , Venkatesan Velprashanth , Chakravarty Rahul 
Published: October 2023

Background:
People who identify themselves as Lesbian, Gay, Bisexual, Transgender, Queer, and others (LGBTQ+) go through a process of self-exploration and self-identification during adolescence, and the process resolves when one decides to self-disclosure. The experience of ‘Coming Out’ (CO) can be positive, leading to acceptance and a feeling of liberation, or it can be harmful, leading to stigma, humiliation, and discrimination, subsequently leading to significant psychological distress.

Aim:
This study was to do a narrative review on the studies published in the area/topic of CO in youth in the last decade (2012-2022) and to look for factors that act as barriers and facilitators of CO. Additionally, we have tried to look for differences in CO in LGBTQ+ adolescents and youth in the Western world vis-a-vis Indian/Eastern societies.

Materials and Methods:
An extensive literature search in electronic databases, PUBMED, Web of Science, EMBASE, Medline, Scopus, and search engine ‘Google Scholar’ using specific search terms and assessment of all published articles until 20th May 2023 was done.

Results:
Twenty-three studies were found eligible for data extraction, which discussed the problems faced during the CO process. Most of the studies are from developed countries, and only one is from India. Eleven were qualitative studies, 11 were cross-sectional studies, and one was a case study. The qualitative studies focused on generating themes of CO along with various issues/problems faced by the participants. The cross-sectional studies mainly explored parental reactions, stigma, parental support, psychological distress, and perceived stress in the participants. Major themes emerging from the qualitative studies were the experience of prejudice from various strata of society, such as parental, societal, racial, cultural, and religious factors that lead to problems of hiding, internalized homophobia, and anticipatory rejections that put this population under extreme conditions. Limited research is available from Eastern societies. More recently, the new generation of adolescents has taken the help of social media platforms for self-disclosure.

Conclusions:
CO is an elaborate multi-step process that considers the presence of parental/family and societal support, cultural/traditional values, and several psychosocial factors that determine the degree of positive outcomes. Emerging data indicated an improved trend of adolescents deciding to come out to families or in online platforms, both of which are associated with challenges, more in eastern collectivistic societies and developing countries.
EKSTRAKSI PEKTIN KULIT KAKAO (Theobroma cacao L.) MENGGUNAKAN METODE MICROWAVE ASSISTED EXTRACTION DENGAN ASAM KLORIDA
Authors: Prasetyo Adji , Nadir Mardhiyah , Sari Wanda Erwinda , Rahmaniar Zhafirah Zanetti 
Published: October 2023

Produksi buah kakao perkebunan rakyat di Indonesia mencapai 703.600 ton/tahun. Kulit buah kakao mengandung senyawa pektin sebesar 25-29% pada buah kakao muda (mengkal) sedangkan pada buah kakao matang sebesar 8-11%. Pektin digunakan dalam industri pangan, kosmetik, maupun farmasi. Pemisahan pektin dari jaringan buah dapat dilakukan dengan metode ekstraksi. Tujuan dari penelitian ini untuk mengetahui pengaruh rasio bahan terhadap pelarut (b/v) pada ekstraksi pektin dari kulit buah kakao menggunakan metode Microwave Assisted Extraction (MAE). Kulit buah kakao diekstraksi sebanyak 20 gram dengan pelarut HCl 0,25% pada daya 300 watt selama 30 menit menggunakan variasi rasio bahan terhadap pelarut ( 1:15, 1:20, 1:25, 1:30, 1:35, dan 1:40). Hasil ekstraksi dianalisa dengan uji kualitatif FTIR serta uji kuantitatif (rendemen, kadar air, kadar abu, berat ekivalen, kadar metoksil, kadar galakturonat dan derajat esterifikasi). Hasil Analisa uji FTIR pada pektin menunjukkan panjang gelombang gugus fungsi hidroksil (3356,36 cm-1), alkil (2921,99 cm-1), eter (1229,74 cm-1) dan karbonil (1732,82 cm-1). Rendemen terbaik dihasilkan pada variasi rasio 1:20 sebesar 5,74% dengan karakteristik pektin yaitu kadar air sebesar 11,45%, kadar abu sebesar 0,96%, berat ekivalen sebesar 621,30 mg, kadar metoksil 15,17% (metoksil rendah), kadar asam galakturonat sebesar 48,09%, dan derajat esterifikasi sebesar 61,09% (ester tinggi). Hasil analisa karakteristik sudah memenuhi standar IPPA.
Efficacy of Ayurveda Polyherbal Medicine in Polycystic Ovarian Syndrome
Authors: Akanksha Mishra  , Lowkesh Chandravanshi  , Lalit Mohan Bhatt  
Published: October 2023

The most prevalent rising health risk for women of reproductive age is polycystic ovarian syndrome, a heterogeneous endocrine condition. The polycystic ovarian syndrome (PCOS) is a prevalent endocrinopathy that is multifactorial and polygenic and is characterized by several tiny ovarian cysts, oligo-ovulation or anovulation, and indicators of hyperandrogenism, differ from person to person throughout time. Here is a case report of a 15-year-old girl who presented with hirsutism, irregular menstruation and constipation, her USG report showed bilateral PCO pattern. Based on the clinical features, treatment principles adopted are Aam paachana, use of Arthava janana Dravya, Vata anulomana and Granthi nashak chikitsa. Initially, after 2 months of treatment menstruation became normal and marked reduction in the symptoms was found. Moreover, the hormonal level became normal after 6 months of treatment. This case study is an example that PCOS can be effectively managed by adhering to Ayurvedic principles.
Ayurveda Perspective on Visarpa Vyadhi and its Management
Authors: Yogesh T. Kotangale  , Anuja S. Bhojane  , Sumedha Y. Kotangale  
Published: October 2023

Skin is the largest organ of the body which acts as a first line of defense in providing resistance to the body. The aggravation of various Dhatus and Doshas result in skin diseases. More than one-fifty skin related diseases are mentioned in various Ayurvedic texts. They are categorized as Visarpa, Kustha, Shotha, Upadansh etc. Visarpa is a very common disease mentioned in Ayurvedic texts which spreads in body in various directions. It is said to be caused by Varicella zoster virus as per modern concept. It manifests as Daha, Jwara, Anunnatashopha and Vedana. Around 20-30% sufferers of various skin ailments are demonstrated through large community prevalence study. A 40-year-male presented along with the vesicular lesions on his neck region associated with mild fever, itching, and pain on the local lesion. He was administered with 250mg of Kamadudha rasa (plain) twice a day before meals with milk, Chandrakala rasa 250mg twice a day, Paripathadi kwatha 2 tsp twice a day and Shatadhauta ghrita for local application on the lesions. The patient reported on the 5th day with significant relief in the size and shape of the facial lesions and other symptoms. The scars limited to minimal without any inflammatory signs by the 7th day of follow-up. Above medications are two readily available and cost-effective compound Ayurvedic formulations, which can be used in the management of herpes zoster infection, especially in low-resource settings.
Efficacy and safety of Vicia faba L. extract compared with levodopa in management of Parkinson’s disease and an in‐silico phytomedicine analysis
Authors: Nikkhah Karim , Shoeibi Ali , Rezaeitalab Fariborz , Aminzadeh Samira , Sharara Hussein , Abbas-Mohammadi Mahdi , Al-attar Mohammad , Akbari Mohammadeza , Moradi Fereydun , Rakhshandeh Hasan , Saeidi Morteza 
Published: October 2023

Background: Parkinson’s disease is a chronic degenerative disease of the central nervous system, presently lacks an effective therapy for its complex pathogenesis. Agents containing Levodopa can alleviate its symptoms. Hypothesis Vicia faba L. (Fava bean) extract may prove a useful antiparkinsonian agent similar to Levodopa. Methods: Thirty patients with Parkinson’s disease, entered into this cross over clinical study. In the first step, each participant received V. faba L. extract containing 106.5 mg of Levodopa. After a wash out period of 7 days, the patients entered the second step during which they received conventional treatment with Levodopa-C tablets. Blood Levodopa were measured 4 hours and 8 hours after each administration. The Movement Disorder Society-Unified Parkinson’s Disease Rating Scale was employed to measure the therapeutic effects in each step. Additionally, a docking analysis was performed to distinguish the chemical constituents of the plant and six key mediators actively involved in Parkinson disease. Results: The fava bean extract significantly alleviate all studied end points except for tremor at rest and freezing. Wilcoxon Signed Ranks Test showed that there was not a significant difference between rigidity, rising chair, gait and bradykinesia. Docking results of the herb components and standard ligands, indicating that the antiparkinsonian activity of V. faba could presumably be related to many phytochemicals. Conclusion: This study showed a beneficial effect of V. faba L. similar to Levodopa-C. and better compliance due to lower adverse events.
Vatsanabha (Aconitum ferox Wall. ex Seringe): A known Visha but potent medicine W.S.R. Rasa Ratna Samuchchaya
Authors: Gajanan Masal Aishwarya , Abhay Shinde Arati 
Published: October 2023

Ayurveda is an ancient science dominantly focuses on healthy living and mindful life in contrary to other medical sciences. Ayurveda specifically uses herbs and herbo-mineral combinations for the treatment. The herbs described in the classics also include some Vishadravya (poisonous plants) as potent medicine. Anything that results in "Vishannatva" (stress) or "Vishada" (sadness) in the body is "Visha" (poisonous material). Depending on the intensity of toxicity, Ayurvedic classics have classified all poisons into two categories: Mahavisha and Upavisha (less potent toxin). Vatsanabha (Aconitum ferox Wall. ex Seringe) is classified under the Sthavara Visha (poison of plant origin) and Mahavisha. It is the only Mahavisha that is still recognised and available. All Vishadravya should be used after some specific Shodhana (purification). While administering Vatsanabha in the form of Ayurvedic medicines, Shodhana (purification) is an effective technique for minimising its hazardous effects. Although it is Vishadravya, the compounds containing Vatsanabha (Aconitum ferox Wall. ex Seringe) are listed in ‘Essential Ayurveda Medication for Ayurvedic dispensaries, operated under centrally supported programmes of the Government of India. This enlistment affirms its significance in other ways. Nearly 17 percentage of the formulations mentioned in RRS have Vatsanabha as their constituent. Modern research has already proven the analgesic, antipyretic, antioxidant, antimicrobial and many other activities of Vatsanabha. Thus, the present review is designed to extensively discuss and understand the safety profile of Vatsanabha and utility in various diseases, along with its probable mode of action.
Evaluation of acute toxicity of Rasaparpati - An Ayurvedic mercurial compound in Albino rats
Authors: Meher Lily , Ratha Kshirod Kumar , Das Arun Kumar 
Published: October 2023

Background
This study aimed to investigate the preparation process of Rasaparpati, an Ayurvedic medicine containing Mercury that is commonly used to treat various ailments. The dangers of using Mercury as a therapeutic agent are acknowledged, and Ayurveda emphasizes purifying heavy metals before human use. The present study assessed the acute toxicity of Rasaparpati in albino rats to ensure its safe consumption.
Methodology
Following ethical guidelines and O.E.C.D. (423) protocol, Rasaparpati was prepared traditionally, and an acute toxicity study was conducted. Two groups of female Wistar rats were administered 300mg/kg and 2000mg/kg of Rasaparpati, and their behavioral changes, signs of toxicity, and mortality were closely monitored. Hematological, biochemical, and histopathological parameters were also examined for any changes. The data obtained were analyzed and evaluated using an unpaired t-test, with p < 0.05 considered significant.
Results
No deaths were observed following the administration of Rasaparpati in an acute toxicity study. There were no hematological or biochemical toxicity indications, even at ten time the therapeutic dose. However, the histopathological analysis revealed mild changes likely to heal and repair. These non-specific and reversible changes in rat cells suggest similar outcomes in human cells.
Conclusions
The acute toxicity study of Rasaparpati suggests its safety for animal use, indicating potential safety for human consumption. No adverse effects or mortality were observed, even at a dosage ten times higher than the therapeutic dose. However, more extensive research with larger sample sizes and control groups is recommended.
Clinical study of add on effect of Triphaladaruadi Kwatha (Vangsenokta) along with antidiabetic drug in management of Prameha (Non-Insulin Dependent Diabetes mellitus- NIDDM)
Authors: Lagad Abhilasha C , E Gogate Vishwas , Khan Almas Y , Kombe Pooja S , N Mane Pallavi , Abhijit Shekhar  
Published: October 2023

Prameha (Diabetes mellitus) is an age long disease known from vedic period and now it is a leading lifestyle disorder. Diabetes mellitus is a group of metabolic syndromes of fat, protein and carbohydrate which is due to absolute or relative deficiency of insulin. The prevalence of diabetes in India has risen from 7.1% in 2009 to 8.9% in 2019.1 The estimates in 2019 showed that 77 million individuals had diabetes in India, which is expected to rise to over 134 million by 2045.2 In India, it is also 3rd leading cause of death (After heart disease and cancer). The number is projected to be twice by 2030. Type 2 diabetes makes up about 85-90% of all cases. Increase in the overall diabetes prevalence rates largely reflect an increase in risk factors for type 2, notably greater longevity and being overweight or obese. Hence preventive measures are essential and an ideal therapy is still obscure. It remains one of the baffling enigmas for clinical research. This is a randomized single blind standard controlled clinical trial conducted on 66 patients of Prameha (Type II DM & who are on antidiabetic treatment) to rule out Add on effect of Triphaladaruadi kwath of either gender between age group of 40-60 years and grouped into Group A & Group B. 33 patients in group A were on Antidiabetic drug (Metformin 500mg OD/BD and 33 patients in Group B are on same antidiabetic drug (Metformin 500mg OD/BD) with additional Triphaladaruadi kwath (Decoction) for 3 months. Results obtained in subjective and objective parameters were analyzed for the statistical significance by adapting paired ‘t’ test in the groups, Two-way ANOVA test between the groups, and Wilcoxon rank sum test. The study revealed that Group B was found to be more effective in bringing symptomatic relief and improving biochemical markers in the patients of Prameha.
Role of Panchakarma in the Management of Spinal Canal Stenosis - A Case Study
Authors: G Anjali , T Sangeeta , M Parappagoudra , G Dash 
Published: October 2023

Spinal canal stenosis is a painful, degenerative condition, and is localized to facets, joints, and ligamentum flavum of the vertebra which is often referred to for surgical correction. The main cause of stenosis is herniated vertebral disc. If there is no compression, the spinal canal can be referred to as narrow, but not stenotic. Certain studies have defined lumbar spinal stenosis as the narrowing of the osteo-ligamentous vertebral canal or the intervertebral foramina, which causes compression of the thecal sac or the caudal nerve roots. The narrowing may impact the entire canal or just a portion of it, but it occurs at a single vertebral level. In this condition, it may, drastically affect the quality of life due to severe pain in doing daily routine activities. In contemporary science, there is no treatment except surgical intervention which is having a high chance of complication and the chances of recurrence. Surgery is necessary when there are clinically significant motor deficiencies or symptoms of cauda equina syndrome. Based on the manifestation of clinical signs and symptoms it can be correlated with Gridhrasi, according to Ayurveda. Gridhrasi can be treated successfully by the intervention of Panchakarma procedures along with Shamana Chikitsa. Here is a case study of a patient suffering from low back pain radiating to bilateral lower limbs, stiffness, numbness, burning sensation in the bilateral sole region, and unable to walk without support, who was previously diagnosed as a case of Spinal Canal Stenosis. He was treated with a Panchakarma procedure, Shamana Chikitsa along with Physiotherapy Exercises. The patient showed marked improvement and could do daily routine activities properly.
КЕЙІНГІ ҰРПАҚ ЖЕЛІЛЕРІНДЕ ШАҒЫН ҰЯШЫҚТЫ ОРНАЛАСТЫРУДЫ ЗЕРТТЕУ
Authors: К. Н. Тайсариева  , Г. С. Джобалаева  , А. А. Абдыкадыров  , А.Хабай  , Ж.Ш.  Тәуірбек  
Published: October 2023

"Қазіргі уақытта орналастырылған 4G сыртқы жылжымалы желілерінің көпшілігі макростарға негізделген. Алайда, макростатистика кең географиялық аймақтарды қамтитын тығыз қамтуды қамтамасыз ету қиын қысқа кідіріс уақыты және жоғары өткізу қабілеттілігі кейбір 5G қосымшалары үшін қажет етеді [1]. Бұл мақалада кең ауқымды MIMO жүйелерінің спектрлік тиімділікті жақсаруы және шағын ұяшықтарды тығыз орналастыру және орналастыру кезінде туындайтын мәселелер, сонымен қоса 5G технологиясының өткізу қабілеттілігінің талаптарын қанағаттандыру қарастырылды. Шағын ұяшықтар қосымша спектрді бөлуді қажет етпестен желінің өткізу қабілетін арттырады, бұл оларды жиілік спектрі аз операторлар үшін немесе спектр жеткіліксіз болған жағдайда тартымды етеді[3]. Сонымен қатар, салада қолданыстағы 4G желілерінің сапасын жақсарту мақсатында тығыз дамыған қалалық жерлерде шағын ұяшықтарды орналастыру 5G технологиясы мен eMBB алғашқы қызметтерінің өткізу қабілеттілігіне қойылатын жоғары талаптарды қанағаттандыру зерттелді. Бұл мақалада nrDLCarrierConfig функциясын қолдана отырып, жаңа NR радиотолқынның 5G төмен түсетін арнасының толқын пішінін қалай параметрлеу және модельдеу керектігі көрсетілген. MATLAB модельдеу ортасында 5G желісінде HDL-кодты генерациялау үшін бейімделген модель құрылды. Бірінші кезекте бұл 5G New Radio (NR) сигналдарын генерациялау, нәтижесінде төмен жиіліктегі қалыптасқан сигналдың есептеулері алынды. Бұл жағдайда F-OFDM сигналдарын генерациялау бойынша осы құралдың мүмкіндіктері қарастырылды. Кілтті сөздер: 5G, шағын ұяшықтар, MIMO, New Radio (NR) антенна, өткізу қабілеті. "