bluuebunny/crossref_metadata_2025_split huggingface dataset:
Abstract A013: Advancing colorectal cancer outreach & screening strategies: Tailoring approaches for two-spirit and urban Native LGBTQIA2S+ populations
Authors: Abrams Corinne E. 
Published: December 2023

Abstract
Background: The focus of this one-year collaborative initiative between the Center for Indigenous Cancer Research at Roswell Park and Northwestern University’s Institute of Sexual and Gender Minority Health and Wellbeing is to refine and customize an existing colorectal cancer (CRC) screening program to suit the unique needs of Two-Spirit and Native American LGBTQ+ urban populations. This undertaking, grounded in exploratory and explanatory qualitative methodologies, is not intended to test a predefined hypothesis, but rather aims to learn, understand, and adapt based on community input and participation. Methods: The project's methodology incorporates two main objectives: (Objective 1) Conducting virtual roundtables with representatives from the Two-Spirit and Native LGBTQ+ community in NYC, with the goal of understanding indigenous perspectives on CRC outreach and screening, and to garner insights on how to tailor these interventions for Native sexual and gender minority populations in urban settings; (Objective 2) Applying qualitative data gleaned from Objective 1 to modify NCI-endorsed materials, with the aim of more effectively conveying outreach and screening information to Two-Spirit and Native LGBTQ+ urban communities. Results: The initiative has engaged a Two-Spirit artist and educator to assist in the organization and co-facilitation of six virtual roundtable conversations, involving a total of 14 participants. Each 90-minute dialogue aimed to solicit input on current education materials, as well as suggestions for their adaptation. A team of five Northwestern University medical students collaborated on the project, contributing to the analysis of the collected qualitative data. Next Steps: Findings from this initiative will offer crucial insights into how the visuals, messaging, and information contained in the S2S colorectal cancer education materials can be revised to better engage Two-Spirit and Native LGBTQ+ individuals. By the project's conclusion, partners will possess clear, community-informed directives on how to adapt CRC outreach and screening resources, paving the way for future testing and implementation.
Citation Format: Corinne E. Abrams. Advancing colorectal cancer outreach & screening strategies: Tailoring approaches for two-spirit and urban Native LGBTQIA2S+ populations [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr A013.
Abstract A027: Creating partnerships to deliver community-based interventions for cancer prevention in a historically African American community
Authors: Rechis Ruth , Gardiner Haley , Oestman Katy , Nutt Stephanie , Walsh Michael T. 
Published: December 2023

Abstract
Be Well Communities™ is MD Anderson’s signature place-based approach for cancer prevention and control, working with communities to promote wellness and address modifiable risk factors for cancer. In this project, the planning phase of the Be Well Communities’ model was implemented in Acres Homes, a neighborhood in northwest Houston with more than 57,000 residents. While the changing demographics show increasing numbers of residents of Hispanic descent (43% of the population), Acres Homes still experiences effects of a legacy of Blacks experiencing poverty; more than half of the population of Acres Homes resides in census tracts that are considered areas of persistent poverty. Further, it is a medically underserved area with relatively high rates of unhealthy behaviors, as compared to Healthy People 2030 goals. To work toward addressing the disparities in health outcomes experienced by community residents, a community advisory group (Steering Committee) including residents, non-profit organizations, health care partners, city and county agencies, plus other stakeholders, was convened and aligned through a structured process to develop shared goals, foster multisector collaboration (as measured by a stakeholder survey administered twice), and enhance community capacity to improve health outcomes through development of a Community Action Plan. Clear, achievable goals were developed, multisector collaboration was enhanced, and more than 400 hours of capacity building support led to a Community Action Plan focused on healthy eating and active living, including 15 evidence-based interventions led by 18 organizations. The majority (93%) of the Steering Committee reports that this plan reflects community priorities and will reach the residents most in need. In the first 2 years of implementation nearly 40% of the residents of the community have been reached by programs including more than 5,000 residents participating in physical activity opportunities, classes and over 1000 individuals receiving outreach from a Community Health Worker within the safety-net hospital system to receive access to healthy food access and nutrition education programming. By listening and developing trust, the Be Well Communities team successfully worked with Acres Homes residents and organizations to enhance community capacity to address health inequities in one of Houston’s most historic communities.
Citation Format: Ruth Rechis, Haley Gardiner, Katy Oestman, Stephanie Nutt, Michael T. Walsh Jr.. Creating partnerships to deliver community-based interventions for cancer prevention in a historically African American community [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr A027.
Abstract A047: Increasing cancer-related community-engagement strategies among Historically Black Colleges and Universities and Minority Serving Institutions
Authors: Jeremiah Rohan D. , Murray Marcus , Standifer Maisha , Kendall LeChaun , Wright Carrie , Savonen Candace , Leeks Jeff 
Published: December 2023

Abstract
Addressing cultural beliefs and barriers is imperative to successfully designing and implementing behavior change interventions to increase cancer screening and treatment among underserved communities. Community-based participatory research (CBPR) fosters proven strategies that reduce barriers to cancer screening in several diverse population groups. Citizen scientists are laypersons who do not have formal science training but receive training to engage in research efforts responsive to community needs. Project Brotherhood, a community-based health organization on Chicago’s southside, has developed a community engagement model known as the Murray Model. It specifically engages black men in improving their health status. One aspect is engaging black men as citizen scientists to address cancer disparities within their communities. Evidence shows that citizen scientists were better equipped to understand lung cancer risks and increased their advocacy for better health within their communities. In partnership with Project Brotherhood and the University of Illinois Cancer Center, the National Cancer Institute, Informatics Technology for Cancer Research (ITCR) Training Network (ITN) Program is scaling up the citizen scientist Train-the-Trainer program at historically black colleges and universities and minority-serving universities. The Train-the-Trainer ITCR citizen scientist program is partnering with the Morehouse School of Medicine to increase its community and academic capacities in the Atlanta metro area to address cancer disparities.
Citation Format: Rohan D. Jeremiah, Marcus Murray, Maisha Standifer, LeChaun Kendall, Carrie Wright, Candace Savonen, Jeff Leeks. Increasing cancer-related community-engagement strategies among Historically Black Colleges and Universities and Minority Serving Institutions [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr A047.
Abstract A070: The influence of cultural factors on health-seeking behaviors regarding prostate cancer among African immigrant men in the United States
Authors: Kaninjing Ernest , Ogunsanya Motolani , Van Voorhis Kaitlin , Asiedu Gladys , Kokayi Assata , Brennan Rae Walker , Young Mary Ellen , Odedina Folake 
Published: December 2023

Abstract
Background: The increasing number of African immigrants in the United States has contributed to the diversity of the country's Black population. However, there is limited research on the impact of immigration, particularly regarding chronic diseases like cancer, within the sub-Saharan African immigrant (SSAI) community. To address this gap, this study aimed to explore cultural factors among SSAIs to better understand the drivers of health disparities in prostate cancer outcomes. Methods: A qualitative approach using grounded theory was employed for this study. Participants were purposefully recruited to reflect the cultural diversity among SSAIs. Recruitment occurred at health fairs, community events and by snowball approach. In-depth interviews were conducted with 16 participants, including prostate cancer survivors. Nine participants have lived in the US for at least 10 years. The average age of participants was 51 years. Country of birth for study participants include, Nigeria, Ghana, Cameroon, Kenya, and Ethiopia. Interviews were transcribed, verified, and de-identified then imported into NVivo 12 software. Four research team members, three of them African immigrants, performed open and axial coding, with consensus on the emerging findings. Results: This study identified several key cultural factors influencing SSAI men’s health behaviors. These factors include the perception of cancer in their country of birth, the low priority given to preventative care in their country of origin, and reluctance to embrace a Westernized diet, the perception of cancer in their country of origin as a death sentence, viewing cancer as a spiritual/religious attack, and associating cancer with affluence. In addition, these cultural factors made participants hesitant to discuss cancer, relying on religion for healing instead of medical care, and seeking healthcare only for cure. Conclusion: This study illuminates key cultural factors among SSAI men that influence their health-seeking behaviors. These findings highlight the need for culturally tailored behavioral interventions to address these factors and improve health outcomes within this understudied population.
Citation Format: Ernest Kaninjing, Motolani Ogunsanya, Kaitlin Van Voorhis, Gladys Asiedu, Assata Kokayi, Rae Walker Brennan, Mary Ellen Young, Folake Odedina. The influence of cultural factors on health-seeking behaviors regarding prostate cancer among African immigrant men in the United States [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr A070.
Abstract A118: Prevalence and risk factors of breast cancer diagnoses among Native Hawaiian & Pacific Islander women
Authors: McNally Sarah A. , Salas-Escabillas Daniel J. , Sowizral Nicholas A. , Panapasa Sela V. 
Published: December 2023

Abstract
Purpose: Breast cancer is the most common type of cancer for women nationally with evidence indicating clear racial and ethnic disparities in risk and occurrence. Yet our understanding of the distinct, population-level impacts among Native Hawaiian and Pacific Islander (NHPI) women is limited. NHPIs show elevated levels of multiple comorbidities and emerging evidence from local community studies suggests NHPIs suffer disproportionately from higher incidence, advanced stage of diagnoses, and lower survivability rates from breast cancer. The purpose of this study was to investigate the prevalence, sociodemographic characteristics, and risk factors associated with NHPI women diagnosed with breast cancer. Methods/Data: We utilized the 2014 Native Hawaiian and Pacific Islander National Health Interview Survey (NHPI NHIS), a nationally representative survey conducted by the CDC-NCHS to collect high-quality data on health conditions, health risk behaviors, and healthcare utilization among NHPI populations. Among 2,588 participants, 4% reported having ever been diagnosed with cancer, and among those breast cancer was the most common. Descriptive and regression analysis of socio-demographic characteristics, risk behaviors, and comorbidities to evaluate disparities in the incidence of breast cancer among NHPI women compared to other racial or ethnic populations. Findings/Conclusion: Population-based estimates of breast cancer prevalence among a diverse NHPI population show breast cancer inequities persist. Ongoing research is needed to better understand the underlying conditions and risks, prevention, and treatment of breast cancer in the population.
Citation Format: Sarah A. McNally, Daniel J. Salas-Escabillas, Nicholas A. Sowizral, Sela V. Panapasa. Prevalence and risk factors of breast cancer diagnoses among Native Hawaiian & Pacific Islander women [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr A118.
Abstract B043: Challenges in managing cancer patients with congenital coronary artery anomalies: A case report
Authors: Khan Aliya M. , Urisote Sophia Navajas , Sheikh Danish A. 
Published: December 2023

Abstract
Introduction: Congenital coronary artery anomalies are rare cardiac abnormalities that can increase the risk of sudden cardiac death, particularly during exercise. Patients with cancer and concurrent coronary artery disease face higher mortality risks, as they often receive delayed percutaneous coronary intervention. Additionally, anthracycline chemotherapy, commonly used in cancer treatment, can cause cardiotoxicity and worsen pre-existing cardiac abnormalities. Despite the complexity of managing cancer patients with coronary artery anomalies, there is a lack of clear guidelines and consensus on optimal approaches. This report presents a unique case of a patient with a malignant inter-arterial course of the right coronary artery and newly diagnosed Human T-lymphotropic virus type I-associated adult T-cell leukemia/lymphoma, discussing the challenges and implications of chemotherapy in such cases. Case Presentation: A 38-year-old male presented with weakness and palpitations, exhibiting abnormal laboratory findings. CT angiography revealed a malignant inter-arterial course of the right coronary artery with severe narrowing. Electrocardiograms showed ST elevations and subsequent T-wave inversions. Despite the increased risk of cardiomyopathy due to the coronary anomaly, the patient required chemotherapy for life-threatening tumor lysis syndrome and refractory lactic acidosis. Anthracycline-based chemotherapy was initiated, and a follow-up echocardiogram after six months showed no acute changes. Conclusion: Managing cancer patients receiving anthracycline chemotherapy remains challenging due to limited guidelines. Anthracycline-induced cardiotoxicity is a concern, especially in patients with pre-existing cardiac anomalies like the malignant inter-arterial course of the right coronary artery. This case emphasizes the importance of recognizing and managing such anomalies in cancer patients to reduce the risk of sudden cardiac death. The higher mortality risk in cancer patients with coronary artery disease highlights the need for guidelines in managing anomalous coronary vessels in cancer patients. Further research is necessary to develop evidence-based strategies for managing cardiac complications in cancer patients, particularly those with pre-existing cardiac anomalies.
Citation Format: Aliya M. Khan, Sophia Navajas Urisote, Danish A. Sheikh. Challenges in managing cancer patients with congenital coronary artery anomalies: A case report [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr B043.
Abstract B050: Effectiveness of biologic agents among Hispanic patients with metastatic colorectal cancer
Authors: Patel Riya , Negassa Abdissa , Tolu Seda , Acuna-Villaorduna Ana , Goel Sanjay 
Published: December 2023

Abstract
Background: Randomized clinical trials have demonstrated the survival benefit provided by the addition of biologic drugs to chemotherapy (biochemotherapy) inpatients with metastatic colorectal cancer (mCRC). However, Hispanic patients are underrepresented in trial populations with limited data on treatment efficacy in them. We aim to ascertain effectiveness of biochemotherapy among Hispanic population in the US with mCRC using a comparitive effectiveness approach. Methods: This study includes two cohorts of patients: (a) age &gt; 65 years mCRCdiagnosed from 2004 to 2011 who had received at least 1 dose of chemotherapyand had complete Medicare claims data using the Surveillance, Epidemiology, andEnd Result (SEER)–Medicare linked database, and (b) local Hispanic population from two hospitals in Bronx, New York, from 2006- 2020. Patient data were classified according to whether they received chemotherapy (oxaliplatin, irinotecan,and 5-fluorouracil or capecitabine) or biochemotherapy (bevacizumab, cetuximab,panitumumab, ramucirumab, or aflibercept, started within 3 months ofchemotherapy). Overall survival (OS) was defined as the time from starting chemotherapy to death or last follow-up. A weighted Cox regression model was used to assess differences in survival. Results: A total of 182 patients with mCRC were identified. Fifty one (28%) received chemotherapy and 131 (72%) received biochemotherapy. Median age was 69 and 68 years, respectively. There were no differences based on median income, marital status, primary site or sidedness, tumor differentiation grades or Charlson Comorbidity Score between both groups. Among patients who received only chemotherapy, 9% received second or greater lines of chemotherapy when compared to 51% in the biochemotherapy group (p &lt; 0.001). The median overall survival was 11.3 (95% CI:6.3 - 19.4) months (mo) and 17 ( 95% CI: 13.0 -25.8) mo, respectively. Biochemotherapy conferred an OS benefit of 39% with average HR = 0.61 (0.40-0.94; p = 0.047). This was 45% in the first two years (HR 0.55). Beyond 2 years, there was an apparent reversal with HR 1.7, suggesting 70% deteriment in OS. Conclusions: In this comparative effectiveness study of a cohort of Medicare recipients and the Bronx population, with mCRC, biochemotherapy was associated with an improvement in OS, especially in the first 2 years. Disclosure: Funded by R21: 1R21AG058027-01 to Sanjay Goel and Abdissa Negassa
Citation Format: Riya Patel, Abdissa Negassa, Seda Tolu, Ana Acuna-Villaorduna, Sanjay Goel. Effectiveness of biologic agents among Hispanic patients with metastatic colorectal cancer [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr B050.
Abstract B056: Inflammatory dietary pattern and risk of multiple myeloma in US Black women
Authors: Patel Anisha V. , Palmer Julie R. , Petrick Jessica L. , Bertrand Kimberly A. 
Published: December 2023

Abstract
Background: Multiple myeloma (MM) takes a disproportionate toll on Black Americans compared to non-Hispanic whites, yet factors related to these disparities remain poorly understood. In a prior analysis of two prospective cohort studies examining diet and MM, a dietary inflammatory pattern was significantly associated with MM risk. Here, we investigate the association between dietary inflammatory index (DII) score and MM incidence in a cohort of US Black women. Methods: The Black Women’s Health Study (BWHS) is a prospective cohort study that enrolled 59,000 US self-identified Black women age 21-69 at entry in 1995. Incident cases of MM, identified among BWHS participants followed by biennial questionnaires, were confirmed via medical record review or linkage with cancer registries. We analyzed food frequency questionnaire (FFQ) data collected in 1995, excluding participants with implausible or missing FFQ data. We also excluded women diagnosed with cancer (other than non-melanoma skin cancer) prior to baseline. FFQ data were used to create a dietary inflammatory index (DII) for each person. The DII score includes total fat and cholesterol as pro-inflammatory dietary contributors, and n-3 PUFAs, selenium, and vitamin D as anti-inflammatory contributors. The DII has been previously associated with six inflammatory markers (CRP, IL-1b, IL-4, IL-6, IL-10, TNF-a). We evaluated associations of DII score quintile with MM incidence using Cox proportional hazards regression, adjusted for age, body mass index (BMI), and total energy intake (kcal/day). Results: Among 55,276 BWHS participants eligible for this analysis, we confirmed 313 incident cases of MM over 26 years of follow-up. Median age at baseline was 38 years old and median BMI was 26.6 kg/m2. The multivariable hazard ratio for women in the top quintile of DII (most pro-inflammatory diet) relative to the lowest quintile (most anti-inflammatory diet) was 0.71 (95% confidence interval: 0.43, 1.16). Conclusions: Overall, DII score was not associated with MM incidence in this cohort of US Black women. Ongoing analyses of markers of dietary inflammation and specific food groups may clarify the possible role of dietary components in MM pathogenesis. Cumulative time-varying models of DII score may also offer more robust conclusions in future analyses.
Citation Format: Anisha V. Patel, Julie R. Palmer, Jessica L. Petrick, Kimberly A. Bertrand. Inflammatory dietary pattern and risk of multiple myeloma in US Black women [abstract]. In: Proceedings of the 16th AACR Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved; 2023 Sep 29-Oct 2;Orlando, FL. Philadelphia (PA): AACR; Cancer Epidemiol Biomarkers Prev 2023;32(12 Suppl):Abstract nr B056.