bluuebunny/crossref_metadata_2025_split huggingface dataset:
Place and infrastructure in the energy transition: Planning with community ties and environmental social value
Authors: Moe Lina , Grubert Emily 
Published: February 2025

Abstract
The energy transition from predominantly fossil- to non-fossil resources will significantly reshape land use and the built environment, and with it, people’s relationships with place. Especially during the infrastructure-intensive “mid-transition” period during which fossil and non-fossil energy systems operate simultaneously with overlapping functions, understanding how people adapt to, value, or resent living with these infrastructures can enable value-informed design and planning efforts. Here, we use conventional qualitative coding methods with machine learning validation to investigate survey responses from people in the US and Australia who already share space with large-scale energy production regarding their natural and social environments. We focus on 1) how individuals use measures of environmental quality to describe not just their natural or physical environment, but also their community; and 2) how and whether shared natural and social spaces facilitate feelings of well-being and belonging, with the goal of informing consultation and planning for the peak infrastructure mid-transition period. We find a blended understanding of nature and culture, with respondents noting tradeoffs from hosting powerful local industry, but also the value of nature as an antidote to deteriorated or low-quality social spaces. We observe a resistance to change paired with a keen sense of loss of local control such that industry is perceived as an outside force, even when formative for local culture and landscapes. Green spaces and good quality air and water are not just measures of how well the environment is doing, but also a benchmark people use to describe how well their community is doing. Themes are notably consistent across the communities included in this analysis, diverse in their size, resource endowment, and industrial history. This work suggests attention to safeguarding and expanding the shared spaces, institutions, and economies that foster strong social ties could improve community outcomes during transition.
Khatag Zamyak’s Co-Seeing
Authors: Hartmann Catherine 
Published: February 2025

Abstract
This chapter considers an ordinary pilgrim’s practices of seeing and how they shape his experience of pilgrimage. It focuses on the pilgrim diary of Khatag Zamyak (1896–1961), a merchant who traveled across Tibet in the 1940s and, in particular, his experiences at Kailash. It shows how Khatag Zamyak employs a variety of practices of seeing, including close looking, visualizing, reading the landscape, recognizing particular sites, identifying signs, and reading narratives of particular masters who traveled to the site or histories of the site itself. Through these practices, Khatag Zamyak constantly draws his focus back and forth between ordinary perception and imaginative vision, a process described as “interweaving worlds.” These practices culminate in Khatag Zamyak reporting a visionary experience, where he claims to have seen the face of the legendary saint Milarepa.
Variations on Tyranny
Authors: Scribano Emanuela 
Published: February 2025

Abstract
This essay analyzes the definition of tyranny proposed by Pascal: ‘Tyranny is wanting to have by one means what can only be had by another.’ The definition of tyranny depends on a basic thesis of Pascalian philosophy, according to which there are different ‘orders’ that structure reality. The essay traces the evidence of Pascal’s legacy in Montesquieu’s use of tyranny. The components of the spirit of nations in Montesquieu’s Esprit des lois—laws, mores, and manners—have the characteristics of Pascalian orders; that is, they are systems governed by specific ends and means that are not transferable to another system. Like Pascal, Montesquieu employs the notion of tyranny to indicate the use in one system of tools specific to another system.
Investigation of trans-to-cis isomerization of cinnamic acid in Arabidopsis using stable-isotope-labeled cinnamic acid
Authors: Tsuzuki Kei , Suzuki Taiki , Nishiyama Kotaro , Seto Yoshiya 
Published: February 2025

Abstract
Cinnamic acid (CA) is a widely distributed metabolite in plant species and is a precursor of many important plant molecules such as lignin and flavonoids. CA exists as both trans and cis isomers; the trans isomer is more common in nature. Previous reports have revealed that the cis isomer of CA (cis-CA) has auxin-like activity when exogenously applied. Moreover, cis-CA was found as the endogenous compound in planta. Here, we report the chemical synthesis of stable-isotope-labeled trans- and cis-CA. Using these labeled compounds as internal standards, we developed a quantification method of CA using LC–MS/MS. We identified cis-CA in diverse plant species, including liverwort, moss, and lycophyte implying an important role of cis-CA in the terrestrial plant kingdom.
Biological and biochemical studies on cell surface functions in microorganisms used in brewing and fermentation industry
Authors: Abe Keietsu 
Published: February 2025

Abstract
When brewing microorganisms, which include bacteria and fungi, act on solid cereal substrates, the microbial cell surface interacts with the substrate. When microorganisms use sugars and amino acids released by hydrolysis of the substrate, this occurs on the cell surface. Throughout my career, I have focused on functional studies of cell surface molecules such as solute transporters, cell wall components, and bio-surfactants and applied the knowledge obtained to the development of fermentation technologies. In this review, I describe (i) catabolite control by sugar transporters and energy generation coupled with amino acid decarboxylation in lactic acid bacteria; (ii) recruitment of a polyesterase by the fungal bio-surfactant proteins to polyesters and subsequent promotion of polyester hydrolysis; and (iii) hyphal aggregation via cell wall α-1,3-glucan and galactosaminogalactan in aspergilli and the development of a novel liquid culture method with hyphal dispersed mutants lacking these two polysaccharides.
What is the optimal timing for advising patients to wash the treatment areas after laser therapy? A prospective, assessor-blinded, randomized controlled trial
Authors: Han Yue , Chang Rui , Liu Lanjun , Zhu Jiafang , Yu Wenxin , Huang Linting , Fang Wei , Gao Wei , Ma Gang , Shang Ying , Lin Xiaoxi 
Published: February 2025

Abstract

Background
Despite ongoing advancements in medical aesthetics, there remains a lack of consensus regarding a standardized postoperative care protocol following laser treatment for skin pigmentation disorders.

Objectives
To evaluate the influence of postoperative facial cleansing practices on the efficacy and safety of laser therapy among patients diagnosed with pigmentary skin diseases.

Methods
Thirty patients diagnosed with pigmented lesions (freckles and/or solar lentigines) were randomly allocated to two distinct groups. Following treatment with a 755-nm alexandrite laser, patients in one group were instructed to perform water cleansing, while the other followed a water-avoidance care protocol. Follow-up visits were conducted on days 1, 3, 7 and 14 after treatment and 3 months postoperatively. These visits included taking standardized photographs, performing VISIA imaging assessments, collecting patient satisfaction questionnaires and recording any potential adverse events.

Results
No serious complications were reported in either group. Most patients demonstrated improvement in their lesions to varying degrees with a single treatment session. No statistically significant differences were identified between the two groups in terms of postoperative visual analogue scale scores (P = 0.17). VISIA analysis revealed a significant decrease in brown spot count in both groups at the 3-month follow-up compared with baseline, with no significant differences between groups (P = 0.99). The average score of patients’ satisfaction in the water-cleansing group was significantly higher than that in the water-avoidance group (P = 0.039).

Conclusions
Our studies have demonstrated that laser treatment of epidermal hyperpigmentation disorders without strict water avoidance can have equally good results with no added adverse effects.
Right Hemothorax Secondary to Pulmonary Vein Laceration Following Left-Sided Pacemaker Implantation: A Case Report
Authors: Fitouchi S , Faucher L , Labani A , Jesel L , Marzak H 
Published: February 2025

Abstract

Background
Lead perforation is a rare but potentially fatal complication of cardiac device implantation. Atrial lead perforations, though less common than ventricular ones, can have severe consequences, especially in elderly patients with underlying structural heart disease.

Case summary
An 83-year-old male with amyloid and valvular cardiomyopathy underwent dual-chamber pacemaker implantation for third-degree atrioventricular block following transcatheter aortic valve implantation. The active-fixation atrial lead was positioned on the right atrial free wall. Six hours post-implantation, the patient developed hemodynamic instability. Echocardiography revealed a small pericardial effusion, while pacemaker interrogation showed an increased atrial pacing threshold. Chest imaging demonstrated a moderate right hemothorax. Initially, conservative management was recommended. However, the patient's condition deteriorated, progressing to cardiac arrest requiring brief cardiopulmonary resuscitation. Emergency sternotomy revealed a large right hemothorax and laceration of the right upper pulmonary vein in contact with the atrial lead screw. The laceration was repaired, and the atrial lead was repositioned. The patient recovered well and was discharged 5 days after surgery.

Discussion
Lead perforation is an uncommon but potentially severe complication of pacemaker implantation, with an incidence of 0.5-1% of cases. Several risk factors have been identified, including advanced age, low body mass index (BMI), atrial remodeling, and lateral lead placement. In this case, the atrial lead perforation extended from the atrial wall to the right superior pulmonary vein. This case underscores the potential risks associated with lateral lead positioning in geriatric patients and emphasizes the necessity for meticulous lead placement and vigilant post-implantation monitoring to mitigate complications.
Pulmonary Vein Stenosis Requiring Angioplasty or Surgical Treatment Following Pulmonary Vein Isolation: Case Series
Authors: Iwama Haruka , Kamioka Masashi , Watanabe Hiroaki , Ogoyama Yukako , Watanabe Tomonori , Kario Kazuomi 
Published: February 2025

Abstract

Background
Pulmonary vein stenosis (PVS) after pulmonary vein isolation (PVI) is a rare but severe complication. Its severity depends on the cause, number of stenosed veins, and symptoms. For symptomatic patients, angioplasty is the first choice, while surgery is not recommended due to its high invasiveness.

Case Summary
Patient 1: A 60-year-old male developed symptomatic left superior and inferior PVS after two procedures of PVI using radiofrequency energy. 8-mm stent in left-superior and 7-mm stent in left-inferior PV were placed. Patient 2: A 64-year-old male underwent PVI using radiofrequency energy with a high-power short-duration (HP-SD) setting. Although the patient was asymptomatic, CT revealed left-inferior PVS along with infiltrative shadow of the same area. Considering the risk of pulmonary infarction and with the patient’s informed consent, a 7-mm diameter stent was placed. Patient 3: A 56-year-old male underwent PVI with a 28mm-cryoballoon, followed by radiofrequency ablation for bilateral inferior PV reconductions. Subsequently, he developed severe left-inferior PVS, uncontrollable hemoptysis, and pulmonary infarction, necessitating lower lung-lobe resection.

Discussion
Classical PVS often results from multiple radiofrequency ablations, as seen in Patients 1 and 3. HP-SD ablation, as a novel technique associated with specific risks, should also be acknowledged. While PVS treatment is typically for symptomatic cases, it may be justified in high-risk asymptomatic patients, as in Patient 2. Although not first-line, surgery should be considered in cases with refractory symptoms, as in Patient 3.
A rare case of intracardiac thymoma
Authors: Jiang Xiaoqing , Zhi Zheng , Gu Xinru , Liu Kefu 
Published: February 2025

Abstract
Thymoma is one of the most common tumors in the anterior mediastinum, it may invade the cardiovascular directly through surrounding tissues when grows large enough. However, it’s rare for thymomas to invade the heart in an early stage. We report a case of a tiny thymoma invading the cardiovascular.
Economic burden of cardiovascular disease in the United Kingdom (UK)
Authors: Shih Kingsley , Herz Naomi , Sheikh Aziz , O'Neil Ciaran , Carter Paul , Anderson Michael 
Published: February 2025

Abstract

Background and aims
Direct (medical and non-medical) and indirect (production losses and informal care) costs of cardiovascular disease (CVD) have been captured in two previous United Kingdom (UK) cost-of-illness studies, but the areas of long-term care and medical device costs were neglected. We aimed to quantify the economic burden of CVD in the UK from a societal perspective between fiscal years 2019/20 to 2021/22.

Methods
Mixed-methods study in a prevalence-based retrospective review of economic costs focused on the public sector. Top-down costing was applied to the following areas: inpatient hospital care, outpatient specialist care, emergency care, primary care, medications, medical devices, long-term care, production losses to morbidity, and production losses to mortality. Bottom-up costing was used by applying the marginal effects of having a cardiovascular disease on several parameters using survey data from the Survey on Health, Aging, and Retirement in Europe to estimate informal care costs.

Results
The modelling performed shows that the total costs of CVD in the UK in 2021/22 were £29.021 billion (bn), with direct costs of £16.620 bn and indirect costs of £12.402 bn. The breakdown of direct costs for the UK were inpatient care (£6.732 bn), long-term care (£4.649 bn), medications (£1.940 bn), primary care (£1.556 bn), outpatient care (£1.011 bn), emergency care (£327.6 million (mn)), and medical devices (£404.4 mn). The breakdown of indirect costs for the UK were informal care costs (£6.377 bn), production losses to mortality (£4.544 bn), and production losses to morbidity (£1.481 bn).

Conclusion
There is a significant economic burden of CVD in the UK, with the highest direct cost resulting from inpatient care and the highest indirect cost resulting from informal care.
A hidden artefact: how surfactants can distort the results of springtail reproduction tests
Authors: Fischer Jonas , Szabó Borbála , Manikhin Leonid , Filser Juliane 
Published: February 2025

Abstract
Soils are exposed to multiple substance groups, including surfactants, which directly enter soils when they are used as additives in fire-fighting liquids or pesticide mixtures due to their surface tension-lowering properties. The impact of chemicals on soil health is often tested with the springtail reproduction test. We tested the effects of the trisiloxane Break-Thru® S 301 on the reproduction of Folsomia candida in three soils according to Organisation for Economic Co-operation and Development (OECD) guideline 232. Juveniles were extracted either by heat or flotation. In the latter method, recommended by OECD 232, test soil is flooded with water and stirred so that springtails float and swim on the water surface. Additionally, we tested the impact of Break-Thru® S 301 on other life-history endpoints linked with reproduction, namely reproduction investment and hatching success. We found a significant decline of recovered springtails at soil concentrations of Break-Thru® S 301 down to 2 mg/kg in sandy soils when using flotation. However, using heat extraction no effects were found at the same concentrations. Also, reproduction investment and hatching success did not indicate any toxicity of Break-Thru® S 301 to springtails at all. In conclusion, Break-Thru® S 301 reduced the water surface tension in the flotation process so that springtail juveniles just sank and disappeared from the water surface. This artefact potentially can occur for all surfactants tested this way. We propose testing surfactant’s impact on springtail flotation by adding a few drops of surfactant and observing springtails’ sinking behaviour, before testing toxicity. Alternatively, heat extraction or surfactant controls can be applied. Most importantly, these options should be mentioned in the respective guidelines, which are highly relevant for chemical risk assessment.
Plipastatin is a shared good by Bacillus subtilis during combating Fusarium spp.
Authors: Stannius Rune Overlund , Kovács Ákos T 
Published: February 2025

Abstract
Bacillus subtilis a Gram-positive soil dwelling bacterium known for its wide range of bioactive secondary metabolites. The lipopeptide plipastatin produced by most B. subtilis isolates have been shown to exhibit potent anti-fungal activity against plant pathogenic fungi. While the effect of these anti-fungal compounds are well studied in the context of biocontrol, much less is known of their role in the environment, which also harbor non-producing strains of these compounds. Fusarium species produce multiple antibacterial compounds resulting in dysbiosis of the plant-associated microbiome and inhibiting plant beneficial bacteria like B. subtilis. While plipastatin is expected to be important for survival of B. subtilis, not all isolates carry the biosynthetic gene cluster for plipastatin suggesting that the protective effect of plipastatin might be shared. In this study, we investigated the protective effect of plipastatin against Fusarium oxysporum in a co-culture using a producer and a non-producer isolate of plipastatin. We tested the survival of single and co-cultured strains under Fusarium challenge in liquid media and solid agar plates to dissect the influence of spatial structure. Our results highlights that plipastatin protects the non-producer strain in a density dependent manner.
A case report of fatal splenic rupture caused by multiple organ infection following foreign body ingestion in a detainee
Authors: Chen Ke , Li Yingmin , Zhang Guozhong , Zuo Min , Bi Haitao , Shi Weibo , Cong Bin 
Published: February 2025

Abstract
Among forensic and clinical cases, infections caused by the ingestion of foreign bodies are common. In general, timely removal of the foreign body and appropriate treatment prevent serious consequences. We herein report a rare case of death due to massive bleeding caused by splenic rupture following foreign body ingestion. To our knowledge, no similar cases have been reported in the Chinese or international literature, making this case particularly noteworthy. In this instance, the decedent was in a detention centre for a criminal offence and swallowed a wire unnoticed. The wire remained in his stomach for more than 50 days, leading to a severe suppurative infection in the gastric tissue. This resulted in suppurative inflammation affecting multiple organs, including the liver, pancreas, and spleen. The condition ultimately led to the rupture of splenic vessels and the formation of a rare, massive haematoma beneath the splenic capsule. Based on medical records and histopathological findings, we infer that the wire had remained in the stomach for approximately 50 days, triggering severe suppurative infections in multiple organs. The spleen eventually ruptured, and the victim died of massive haemorrhage.
Life-stage dependent behavior mimics chemosensory repertoire diversity in a belowground, specialist herbivore
Authors: Paddock Kyle J , Corcoran Jacob A 
Published: February 2025

Abstract
Insects rely on the translation of environmental chemical cues into behaviors necessary for survival and reproduction. Specific chemosensory receptors belonging to the odorant and gustatory receptor groups detect odorant and gustatory cues, respectively, making them crucial to these processes. How odorant (OR) and gustatory (GR) receptor expression profiles change in combination with changing life strategies is not well understood. Using genomic and transcriptomic resources we annotated the OR and GR expression profiles across all life stages of the western corn rootworm (WCR), Diabrotica virgifera virgifera LeConte, a major pest of corn in the US and Europe. Genomic analyses identified 193 ORs and 189 GRs, of which 125 and 116 were found to be expressed, respectively, in one or more WCR life stages. WCR larvae are subterranean and feed on roots before emerging as adults aboveground. Expression profile analyses revealed first instar larvae possess a unique OR and GR repertoire distinct from other instars and adults, suggesting a role in host plant finding. Similarly, a subset of ORs and GRs differed in their expression levels between adult male and female antennae. By comparing the phylogenetic relationship of ORs and GRs, we identified several receptors with potentially important roles in WCR foraging and reproductive behavior. Together, this study provides support for future investigations into the ecology and evolution of chemoreception in insects.
Who’s On Your Team? Classifying Dementia Caregiving Networks and Associations with the Well-being of Caregivers and Care Recipients with Dementia
Authors: Leggett Amanda N , Haldar Srabani , Tsuker Sophia , Lai Wenhua , Nemmers Natasha , Choi Hwa Jung , Freedman Vicki 
Published: February 2025

Abstract

Objectives
While caregivers are typically enmeshed in broad networks of family and friends assisting with care, this network has been neglected in favor of examining a “primary” caregiver. This study examines types of family and unpaid friend networks for individuals with dementia and how one’s network type relates to the well-being of care recipients with dementia and their caregivers.

Methods
Data are drawn from the nationally representative 2017 National Health and Aging Trends Study and associated National Study of Caregiving. The sample includes 336 dementia care networks (Network size mean=2.9). We first identified network types using Latent Class Analysis and then examined the extent to which network type is associated with the well-being of care recipients with dementia (sleep, depressive symptoms) and their caregivers (emotional difficulty, overload, social support from family and friends) using ANOVA and linear regressions adjusting for demographics.

Results
Three network types were identified: “Siloed”- small networks, limited task sharing (29.8% of networks); “Small but mighty”- small networks, high task sharing (23.0% of networks); and “Complex”- large networks, diverse membership, members who share and specialize in task assistance (47.2%). Individuals with dementia with a “Siloed” network had significantly poorer sleep quality and caregivers in “Siloed” networks reported receiving less social support from family and friends than those in “Small but mighty” and “Complex” networks.

Discussion
Caregiver networks that are less collaborative may need supports to reduce isolation amongst caregivers and improve health outcomes for individuals with dementia.