bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demografia e ciclo de vida de Daphnia Magna, submetida à toxicidade do óleo de andiroba utilizado como repelente natural
Authors: Da Silva Silvana Daniel , Souza Karissa Conceição , Pereira Mária de Fátima Marinho , Keppeler Erlei Cassiano 
Published: February 2024

A Daphnia magna é um organismo modelo comum usado em testes toxicológicos, pois é amplamente distribuída em ambientes aquáticos, e tem um ciclo de vida curto e é fácil de criar em laboratório. Para o cultivo de cladóceros e para experimentos foi usada água natural e algas da espécie Chlorella sorokiniana, como dieta. Para a cultura de Daphnias foi utilizado o meio EPA modificado. E as condições experimentais gerais foram: frascos transparentes de 50 mL, na proporção 1:1, de água do meio e substância teste, nos tratamentos e controle com água do meio, onde cada frasco de teste recebeu 10 neonatos (<24 h) do organismo teste, Daphnia magna. Foram determinados cálculos relacionados à análise demográfica, como duração média de vida, expectativa de vida, taxa bruta de reprodução, taxa liquida da de reprodução, tempo de geração e taxa intrínseca de crescimento populacional. Em geral, a toxicidade do óleo de andiroba promoveu em Daphnia magna, mortalidades em relação ao controle, independente de qualquer concentração testada. Os padrões de fertilidade de D. magna mostraram diminuição na produção de neonatos com o aumento da concentração do óleo de andiroba. Os resultados do experimento indicaram que o óleo de andiroba teve efeitos tóxicos em Daphnia magna, sendo importante para avaliar a segurança desse produto químico, contribuindo significativamente para a compreensão dos riscos associados ao seu uso.
Tecnologias e educação inclusiva: aplicabilidade de softwares para o processo de ensino e aprendizagem de alunos surdos
Authors: Lima Lucas Alves de Oliveira , Francisco Thiago José , Do Nascimento José Leônidas Alves , Peixoto André Alfonso , Gonçalves Gustavo Henrique , Botelho Lissandro , De Morais Sérgio David , Compagnon João Batista Rodrigues Cruz , De Souza Ana Rosa Braga , Fagundes Guilia Rivele Souza 
Published: February 2024

A presente pesquisa teve como objetivo analisar a aplicabilidade de softwares para o processo de ensino e aprendizagem de alunos surdos. A pesquisa adotou uma revisão sistemática de literatura, seguindo as diretrizes do PRISMA. A busca por artigos foi realizada nas plataformas Scielo e Google Acadêmico, utilizando palavras-chave e operadores booleanos "AND" e "OR". Os critérios de inclusão limitaram-se a artigos científicos em português e de nacionalidade brasileira, publicados entre 2020 e 2023, e associados à aplicabilidade de softwares na alfabetização de alunos surdos, com foco na inclusão escolar. A revisão sistemática dos estudos examinados sobre o papel dos softwares educacionais na inclusão de alunos surdos evidenciou a discrepância entre teoria e prática, evidenciando a necessidade de preencher lacunas de conhecimento, especialmente no registro de Libras. Os softwares são enfatizados como facilitadores na língua de sinais, otimizando serviços e desempenhando um papel essencial na promoção do conhecimento. Além de contribuírem para a compreensão do ambiente e suporte no letramento e na educação, essas ferramentas emergem como recursos para criar ambientes educacionais mais acessíveis e inclusivos para alunos surdos. No entanto, os estudos também destacam desafios, como a escassez de pesquisas específicas e a defasagem no desenvolvimento de soluções tecnológicas, ressaltando a necessidade contínua de aprimoramento. A chamada para uma abordagem interdisciplinar na criação de jogos educativos bilíngues sublinha a complexidade da inclusão digital, enfatizando a importância de considerar diversos aspectos para garantir eficácia e respeito às especificidades do público-alvo, integrando as potencialidades dos softwares em várias áreas do aprendizado e desenvolvimento.
Perfil das hospitalizações e óbitos por condições sensíveis à atenção primária no estado do Paraná em 2019
Authors: Rôas Yuri Alexander dos Santos , Costa Maria Antônia Ramos , Peruzzo Hellen Emília , Rôas Francilene Bernardo Cordeiro , De Oliveira Rosana Rosseto , De Melo Willian Augusto 
Published: February 2024

Analisar as Internações e óbitos por Condições Sensíveis a Atenção Primária (ICSAP) no estado do Paraná no período de 2019. Estudo ecológico transversal, retrospectivo, analítico, realizado por meio de dados secundários do Sistema de Informações Hospitalares. Para análise estatística foi utilizado o teste qui-quadrado de Pearson. As hospitalizações por CSAP foi considerada como variável dependente. Calculou-se a odds ratio ajustada para estimar as medidas de associação entre as variáveis Foram registradas 895.905 hospitalizações, sendo 158.773 por CSAP. Os pacientes hospitalizados por CSAP apresentaram maiores riscos de óbito (OR=1,1; IC95%=1,11-1,18) e maior tempo de internamento (OR=2,0; IC95%=1,97-2,02). Custos de internamentos mais elevados apresentaram maior risco de óbito (OR=2,9; IC:2,38-3,42). Um quinto das hospitalizações no Paraná foram por CSAP, o que sugerem maior investimento em ações de promoção da saúde e prevenção na atenção primária, visando a redução de hospitalizações por CSAP.
Percepções de usuárias sobre a assistência à saúde prestada por profissionais do gênero masculino
Authors: Vargas Júnior Gilson André de Sá , Bagé Isabela Teixeira , Mesquita Isadora da Silva , Dos Santos Elitiele Ortiz , Gomes Bruna Cristiane Furtado , Stumm Lilian Konageski , De Siqueira Monalisa Dias , Prates Lisie Alende 
Published: February 2024

Objetivou-se compreender as percepções de usuárias da Atenção Primária à Saúde acerca da assistência à saúde da mulher prestada por profissionais da saúde do gênero masculino. Pesquisa qualitativa, descritiva e exploratória, desenvolvida no contexto da Atenção Primária à Saúde de um município da Fronteira Oeste do Rio Grande do Sul. Participaram da pesquisa 12 mulheres, por meio de uma entrevista semiestruturada individual. Os dados foram submetidos à análise temática de conteúdo. Os achados revelaram vivências de desconforto, vergonha e estranhamento por usuárias ao serem atendidas por uma profissional de saúde do gênero oposto ao seu. Identificou-se que o diálogo, o respeito e a individualidade são estratégias para a usuárias se sentirem mais confortáveis com o profissional. As percepções das usuárias são influenciadas por diversos aspectos, como a habilidade de estabelecer um vínculo de confiança, o respeito às individualidades, a comunicação adequada e o conhecimento demonstrado pelo profissional ou acadêmico. É essencial que aquele que está à frente da assistência esteja atento a essas urgências e proporcione um ambiente acolhedor e seguro para as mulheres.
La collection « Petite Planète » (Seuil) sous la direction de Chris Marker (1954-1958)
Authors: Nerinckx Quentin 
Published: February 2024

À l’instar de toute une série de portraits phototextuels de pays, la collection « Petite Planète » commence à être éditée par les Éditions du Seuil dans une période que Jean Fourastié a nommée les Trente Glorieuses, dans un contexte de développement du tourisme de masse et d’apparition du livre de poche moderne. La personnalité de son directeur — le jeune Chris Marker qui fait alors ses premiers pas dans le monde du livre, de la photographie et du cinéma —, son format de poche, l’originalité de ses couvertures, son accent sur le présent des pays étudiés et leur population, ou encore la recherche et l’expérimentation dans l’utilisation d’une illustration riche et abondante sont autant d’aspects qui font que « Petite Planète » va se démarquer, dès son lancement, des séries concurrentes et affirmer sa singularité dans le paysage éditorial francophone de l’époque.
The Great Forgetting
Authors: diZerega Gus 
Published: February 2024

Why did the modern world enter into a “great forgetting” about the more-than-human world so many indigenous peoples took for granted? Second, how can this previous knowledge be reacquired without rejecting the very real accomplishments of the modern mentality? Many deep ecological writers have done extraordinary work on this second question. I will focus on the first, and use its analysis to add some insights regarding the second.Central to the argument I will make is how language both empowers us and to some degree separates us from direct experience of the other-than-human world. Western languages are particularly prone to reinforcing this separation. Equally central will be a discussion of how media of communication rooted in language further distances us from direct encounter. Also important will be work in contemporary biology and ecology exploring how deeply interconnected all life forms are. The traditional Western idea of individuals, be they plants and animals or human beings, are ultimately irreducibly distinct from their environment has been shown to be mistaken. Individuals have been shown to be made up of simpler individuals who, in relationship with one another, enable emergent qualities to arise at ever greater levels of complexity. Further, while genuinely individual, they cannot be understood without reference to relationships outside what are normally considered individual boundaries.By seeking the foundations of morality and other values in theology, reason, or will, many moderns are blinded to the fact values supporting morality and beauty exist immanently within the natural world. There is no need to import them from elsewhere. By way of conclusion, I reverse direction and describe one method available to the reader how a ‘remembering’ can come about experientially. This remembering will reconnect with an indigenous and sometimes shamanic perception of the world as alive and connected.
Universal Basic Income
Authors: Widerquist Karl 
Published: February 2024

An accessible introduction to the simple (yet radical) premise that a small cash income, sufficient for basic needs, ought to be provided regularly and unconditionally to every citizen.
The growing movement for universal basic income (UBI) has been gaining attention from politics and the media with the audacious idea of a regular, unconditional cash grant for everyone as a right of citizenship. This volume in the Essential Knowledge series presents the first short, solid UBI introduction that is neither academic nor polemic. It takes a position in favor of UBI, but its primary goal remains the provision of essential knowledge by answering the fundamental questions about it: What is UBI? How does it work? What are the arguments for and against it? What is the evidence?
Karl Widerquist discusses how UBI functions, showing how it differs from other redistributional approaches. He summarizes the common arguments for and against UBI and presents the reasons for believing it is a tremendously important reform. The book briefly discusses the likely cost of UBI; options for paying for it; the existing evidence on the probable effects of UBI; and the history of UBI from its inception more than two hundred years ago through the two waves of support it received in the twentieth century to the third and largest wave of support it is experiencing now. Now more than ever, conditions in much of the world are ripe for such enthusiasm to keep growing, and there are good reasons to believe that this current wave of support will eventually lead to the adoption of UBI in several countries around the world—making this volume an especially timely and necessary read.
The effects of selected sedatives on basal and stimulated serum cortisol concentrations in healthy dogs
Authors: Hunt Adam , Olin Shelly , Whittemore Jacqueline C. , Esteller-Vico Alejandro , Springer Cary , Giori Luca 
Published: February 2024

Background
Hormone assessment is typically recommended for awake, unsedated dogs. However, one of the most commonly asked questions from veterinary practitioners to the endocrinology laboratory is how sedation impacts cortisol concentrations and the adrenocorticotropic hormone (ACTH) stimulation test. Butorphanol, dexmedetomidine, and trazodone are common sedatives for dogs, but their impact on the hypothalamic-pituitary-adrenal axis (HPA) is unknown. The objective of this study was to evaluate the effects of butorphanol, dexmedetomidine, and trazodone on serum cortisol concentrations.

Methods
Twelve healthy beagles were included in a prospective, randomized, four-period crossover design study with a 7-day washout. ACTH stimulation test results were determined after saline (0.5 mL IV), butorphanol (0.3 mg/kg IV), dexmedetomidine (4 µg/kg IV), and trazodone (3–5 mg/kg PO) administration.

Results
Compared to saline, butorphanol increased basal (median 11.75 µg/dL (range 2.50–23.00) (324.13 nmol/L; range 68.97–634.48) vs 1.27 µg/dL (0.74–2.10) (35.03 nmol/L; 20.41–57.93); P < 0.0001) and post-ACTH cortisol concentrations (17.05 µg/dL (12.40–26.00) (470.34 nmol/L; 342.07–717.24) vs 13.75 µg/dL (10.00–18.90) (379.31 nmol/L; 275.96–521.38); P ≤ 0.0001). Dexmedetomidine and trazodone did not significantly affect basal (1.55 µg/dL (range 0.75–1.55) (42.76 nmol/L; 20.69–42.76); P = 0.33 and 0.79 µg/dL (range 0.69–1.89) (21.79 nmol/L; 19.03–52.14); P = 0.13, respectively, vs saline 1.27 (0.74–2.10) (35.03 nmol/L; 20.41–57.93)) or post-ACTH cortisol concentrations (14.35 µg/dL (range 10.70–18.00) (395.86 nmol/L; 295.17–496.55); (P = 0.98 and 12.90 µg/dL (range 8.94–17.40) (355.86 nmol/L; 246.62–480); P = 0.65), respectively, vs saline 13.75 µg/dL (10.00–18.60) (379.31 nmol/L; 275.86–513.10).

Conclusion
Butorphanol administration should be avoided prior to ACTH stimulation testing in dogs. Further evaluation of dexmedetomidine and trazodone’s effects on adrenocortical hormone testing in dogs suspected of HPA derangements is warranted to confirm they do not impact clinical diagnosis.
Mathematical Modeling of Bird Harvesting in Intensive Poultry System
Authors: Sunday Udofia, Ekere , Dominic Akpan, Ubong , Ijeoma Uwakwe, Joy , Sylvester Thomas, Henry 
Published: February 2024

This work, presents a formulation of mathematical model of bird harvesting in an intensive poultry system, under the assumption that under a favourable environmental atmosphere and good management system, the birds have logistic growth. The model is analysed using methods from dynamical system theory and theory of calculus. It was established that the system has two steady state, the two equilibrium state are both locally asymptotically stable. The first one is stable if there is a bound on the harvest rate of the birds, which is proportional to the growth rate of the birds. The second equilibrium state is locally asymptotically stable (LAS) if k < \(\frac{r(C+y)}{p}\) that is if the carrying capacity is less than the ratio of the sum of and Per unit tax on the bird to that of Per unit price of the birds. Further analysis indicates that the limiting population of bird, that is the maximum population of birds that the available resources in the system can sustain and also ensures harvesting profitability is given as
How Pedagogues Support Inclusion in Denmark: Experiences, Barriers, and Recommendations
Authors: Gulløv Cristina , Murawski Wendy W. 
Published: February 2024

Abstract
Danish school reform around inclusive practices became more prevalent in 2014, and efforts to address the needs of children with disabilities increased. One of the primary ways to meet students' needs in an inclusive setting was to move pedagogues out of their traditionally after-school social settings into the general education classroom to co-teach with content teachers. This qualitative study followed groups of pedagogues and classroom teachers in Denmark for two years, using interviews and observations to ascertain the challenges and successes of co-teaching between pedagogues and teachers. The results mirror in many ways the current research on co-teaching in other countries and with other collaborating professionals. The challenges, barriers, and successes experienced by pedagogues and teachers who were expected to co-teach due to Danish school reform on inclusion are shared. Recommendations build on existing literature and address the unique role that Danish pedagogues can play in moving inclusive practices forward and how their experiences can be applied to co-teachers in other countries and settings.
Stochastic Sensing of TNT with a Genetically Engineered Pore
Authors: Guan Xiyun , Gu Li‐Qun , Cheley Stephen , Braha Orit , Bayley Hagan 
Published: August 2005

AbstractEngineered versions of the transmembrane protein pore α‐hemolysin (αHL) can be used as stochastic sensing elements for the identification and quantification of a wide variety of analytes at the single‐molecule level. Until now, nitroaromatic analytes have eluded detection by this approach. We now report that binding sites for nitroaromatics can be built within the lumen of the αHL pore from simple rings of seven aromatic amino acid side chains (Phe, Tyr or Trp). By monitoring the ionic current that passes through a single pore at a fixed applied potential, various nitroaromatics can be distinguished from TNT on the basis of the amplitude and duration of individual current‐blocking events. Rings of less than seven aromatics bind the analytes more weakly; this suggests that direct aromatic–aromatic interactions are involved. The engineered pores should be useful for the detection of explosives and, in combination with computational approaches and structural analysis, they could further our understanding of noncovalent interactions between aromatic molecules.
Psychological responses to cancer recurrence
Authors: Andersen Barbara L. , Shapiro Charles L. , Farrar William B. , Crespin Timothy , Wells‐DiGregorio Sharla 
Published: August 2005

AbstractBACKGROUNDThere is a dearth of knowledge regarding the psychological responses to a diagnosis of cancer recurrence.METHODSAn ongoing randomized clinical trial provided the context for prospective study. Women with Stage II/III breast carcinoma (N = 227) were initially assessed after their diagnosis/surgery and before adjuvant therapy and then reassessed every 6 months. Eight years into the trial, 30 patients had recurred (R) and were assessed shortly after receiving their second diagnosis. Their data were compared with a sample of trial patients who had no evidence of disease (disease free [DF]; n = 90). The groups were matched on study arm, disease stage, estrogen receptor status, menopausal status, and time since initial diagnosis.RESULTSAs hypothesized, patients' cancer‐specific stress at recurrence in the R group was higher (P < 0.05) than stress levels for the DF group at the equivalent point in time. Importantly, the R group reported stress for their recurrent diagnosis equivalent to that reported for their initial diagnosis. Identical results were found for measures of health status and symptomatology. In contrast, analyses for emotional distress and social functioning showed no pattern of disruption for the R group at cancer recurrence and levels equivalent to that of the DF group.CONCLUSIONSTo the authors' knowledge, this was the first controlled, prospective psychological analysis of patients' responses to cancer recurrence. The findings were consistent with a learning theory conceptualization of the cancer stressor. Patients' stress was “compartmentalized” and did not, at least in the early weeks, result in diffuse emotional distress and quality of life disruption, underscoring the resilience of patients when confronted with cancer recurrence. Cancer 2005. © 2005 American Cancer Society.
Impact of brachytherapy on regional, racial, marital status, and age‐related patterns of definitive treatment for clinically localized prostate carcinoma
Authors: Copeland Laurel A. , Elshaikh Mohamed A. , Jackson James , Penner Louis A. , Underwood Willie 
Published: August 2005

AbstractBACKGROUNDThe impact of the increased use of permanent prostate brachytherapy compared with other treatment modalities (such as radical prostatectomy and external‐beam radiation therapy [EBRT]) for the treatment of clinically localized prostate carcinoma, and the previously reported regional, racial, and age‐related variations in prostate carcinoma treatment, have not been well characterized to date. Therefore, the authors evaluated the impact of permanent prostate brachytherapy on the relative rates of the use of specific prostate carcinoma treatment modalities over time.METHODSSurveillance, Epidemiology, and End Results (SEER) cancer registry data from 1995 to 2000 were analyzed in a longitudinal, observational study utilizing bivariate and multivariate techniques.RESULTSDifferential changes in the use of specific definitive treatment modalities were noted by region, age group, racial/ethnic group, and marital status. Increasing use of permanent prostate brachytherapy, with and without concomitant EBRT, was proportional to the decreasing use of radical prostatectomy alone and EBRT alone over time.CONCLUSIONSThe current study revealed that permanent prostate brachytherapy appears to be replacing other treatment modalities in increasing numbers of clinically localized prostate carcinoma cases. Persistent regional, racial/ethnic, marital status, and age‐related differences in the use of permanent prostate brachytherapy merit further investigation. Cancer 2005. © 2005 American Cancer Society.
Nasopharyngeal intracavitary brachytherapy
Authors: Leung To‐Wai , Tung Stewart Y. , Wong Victy Y. W. , Sze Wing‐Kin , Lui Collin M. M. , Wong Frank C. S. , Lee Ann‐Shing , O Sai‐Ki 
Published: August 2005

AbstractBACKGROUNDLocally persistent nasopharyngeal carcinoma (NPC) carries an increased risk of local failure if additional treatment is not given. It has been shown that intracavitary brachytherapy is effective in the treatment of patients with T1 and T2a NPC, although its role in the treatment of T2b disease had remained uncertain. The objectives of the current study were to evaluate the outcomes of patients with T2b, locally persistent NPC who were treated with high‐dose‐rate (HDR) intracavitary brachytherapy and to explore whether routine brachytherapy boost could improve the local control of patients who had T2b NPC at initial diagnosis.METHODSThirty‐four patients with locally persistent NPC who were treated during 1992–2000 with HDR intracavitary brachytherapy were analyzed retrospectively. All patients had T2b disease at initial diagnosis. They were treated with HDR intracavitary brachytherapy at doses of 22.5–24.0 grays (Gy) in 3 weekly sessions. To compare the efficacy of brachytherapy, another 403 consecutive patients with nonmetastatic T2b NPC who were treated with curative intent by external radiotherapy (ERT) during the same period were evaluated.RESULTSAn improvement in the 5‐year actuarial local failure‐free survival rate (brachytherapy group vs. ERT group: 96.9% vs. 81.5%; P = 0.024), the disease‐specific survival rate (84.5% vs. 68.1%; P = 0.021), and the overall survival rate (78.3% vs. 63.1%; P = 0.034) was demonstrated in the group that had locally persistent NPC who were salvaged with brachytherapy. In assessing local control, the addition of brachytherapy was just short of statistical significance on multivariate analysis (P = 0.054). The complication rates were comparable between the brachytherapy group and the ERT group.CONCLUSIONSThe results suggested that patients with T2b NPC who have locally persistent disease can be salvaged effectively with brachytherapy. Their local control was even better than that achieved by patients who had clinical remission of local disease at the completion of ERT. Furthermore, it is possible that routine brachytherapy boost, after the completion of ERT, may improve local control in patients who have T2b disease at initial diagnosis. However, its exact benefit can be elucidated only by prospective, randomized studies. Cancer 2005. © 2005 American Cancer Society.