bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ascertaining the Effectiveness of Coordination Training Interventions in Enhancing Sports Performance: A Systematic Review and Meta-analysis
Authors: Saini Ashwani , Dubey Bipin Kumar , Vishwakarma Rakesh 
Published: January 2025

Objectives. The study aimed to analyze the effects of training programs that focused on various coordination exercises to improve the sports performance and coordination of athletes.
Materials and methods. An electronic review was conducted to compile the literature related to this issue, using Scopus, PubMed, Google Scholar and ProQuest databases. Following a systematic search, eleven studies carried out between 2014 to 2024 were considered appropriate for meta-analysis and were retrieved and analysed. The studies included were confined to different coordination interventions, such as balance, rhythm, agility, neuromuscular training, jump ropeladder exercises, spatial orientation, non-sports specific and proprioceptive training, ranging from 6 weeks to an annual macrocycle with participants (sub-junior and junior levels) from different sports.
Results. The meta-analysis revealed a small effect size improvement for balance training (E = 0.38; 95 % CI = -0.66-2.54; p = 0.25), a large effect size and significant enhancement for coordination and rhythm training (E = 2.2; 95 % CI= -0.98-1.45; p = 0.70). Additionally, it was noted a moderate effect size and substantial improvement for a specific coordinative ability training (E = 1.8; 95 % CI = -0.84-2.99; p = 0.00) when compared the experimental group with the control group. The results of 11 studies established a significant effect size of various coordination training interventions in improving motor coordination of athletes. However, the impact of these interventions on sports skills and performance remains limited and inadequate.
Conclusions. After a thorough analysis, it was concluded that various training regimens involving different stimuli, means and methods, comprising proprioceptive training, spatial training, motor rhythm training, neuromuscular training, balance training, coordination training drills using ladders, wobble board, bosu balls, trampoline and dynamic games, as well as non-specific sports training with basic exercises, have been found to be effective in enhancing motor coordination and sports skills.
Effect of sarcopenic obesity on treatment results in patients with malignant tumors of the gastrointestinal tract: systematic review
Authors: Boldyreva T. S. , Lyadov V. K. 
Published: January 2025

Background. Tumors of the gastrointestinal (GI) tract are characterized by high morbidity and poor prognosis. Over the past decade, sarcopenia (skeletal muscle depletion), myosteatosis, sarcopenic obesity were all shown to have negative prognostic effect in patients with various GI malignancies. However, the role of sarcopenic obesity (SO) in patients with GI tumors remains controversial. We have summarized clinical trial data on the effect of SO on treatment results in patients with malignant GI tumors who underwent surgical and/or drug antitumor treatment.Materials and methods. Thisstudy was conducted in comliance with the Preferred Reporting Itemsfor Systematic Review and Meta-Analyses (PRISMA) guidelines. PubMed and Cochrane Library databases were searched for relevant original studies published between January 2009 and December 2022 reporting postoperative complication rate and mortality, long-term survival and chemotherapy toxicity in SO patients with GI cancers.Results. Twenty four studies with 9,601 patients were included. The percentage of SO patients ranged from 2.6 to 51 %. Due to significant heterogeneity of SO determination methods and varying threshold values, the association between SO and outcomes of interest was inconsistent. SO was significantly associated with development of major postoperative complications in six studies. In contrast, three studies did not show any effect of SO on postoperative complications. Only two studies demonstrated that the mortality rate was significantly higher among patients with SO compared to those without SO. Four studies using multivariate analysis showed statistically significant effect of SO on long-term survival, one study – on disease-free survival. However, three trials contradicted this finding and reported that SO was not a negative prognostic factor of long-term survival in GI cancer patients. Three studies investigating SO effect on the outcomes of drug antitumor treatment showed negative effect of SO on chemotherapy toxicity.Conclusion. There is considerable heterogeneity in methods used to define SO in the literature, and current data is limited. Standardized terminology and deeper understanding of sarcopenic obesity pathophysiology is needed to further understand the effect of obesity and sarcopenia on clinical trajectory of patients with GI cancer.
Reseña de: Inmaculada Casas-Delgado, Carlos M. Collantes Sánchez (coord.), La literatura de cordel en la sociedad hispánica (siglos XVI-XX), Sevilla, Editorial Universidad de Sevilla (Colección Literatura), 2022, 349 pp., ISBN: 978-84-472-2316-9
Authors: Castillo Martínez Cristina 
Published: January 2025

Reseña de: Inmaculada Casas-Delgado y Carlos M. Collantes Sánchez (coord.), La literatura de cordel en la sociedad hispánica (siglos XVI-XX), Sevilla, Editorial Universidad de Sevilla, 2022
Os desafios da Atenção Primária à Saúde no acolhimento de crianças e adolescentes vítimas de violência sexual
Authors: Borges Ribeiro Everton , Pereira Stephanie , Terra Maria Fernanda 
Published: January 2025

Objective: to analyze the challenges and strategies of the Violence Prevention Centers (VPC) in supporting children and adolescents who are victims of sexual abuse, as well as their families, within Primary Health Care services. Method: qualitative study conducted using semi-structured interviews with eight professionals working in VPCs. The findings were interpreted through the Content Analysis method. The thematic categories identified were: The pact of silence; Family man and abuser: tensioning roles and imaginaries; Gender inequality and female vulnerability in family relationships; and Implications for professional practice. Results: the study identified challenges in providing care to children and adolescents who have experienced sexual abuse, highlighting the need for multidisciplinary and networked approaches as essential to ensuring comprehensive care. Conclusions: the research underscored the importance of humanized care that accounts for the unique characteristics of everyone, considering the social, moral, ethical, and psychological dimensions that shape their experiences.
Enhancing Morpho-physiological Characters and Productivity of Kharif Groundnut Through Application of Plant Growth Retardants under East and South Eastern Coastal Zone of Odisha
Authors: Lenka S. , Kumar G.S. , Swain S.K. , Dash R.R. , Pradhan K.C. , Sethy A.K. 
Published: January 2025

Background: Groundnut grown in kharif season incurs more vegetative growth with higher plant height which causes the upper aerial pegs not to reach the ground. So, less numbers of sound mature pods resulting in lower yield compared to other seasons. The aim of the following investigation was to examine the effect of different growth regulators on plant height including other morphological and physiological parameters of kharif groundnut. Methods: The experiment was conducted during kharif sesaons of 2021 and 2022, taking three growth regulators with different concentrations in main plot i.e. Cycocel (CCC) @ 500 and 1000 ppm, Brassinosteroides (BR) @ 10 and 15 ppm, Maleic hydrazide (MH) @ 100 and 200 ppm and scheduling of applications in sub plots i.e. 30 DAS, 50 DAS and 30 and 50 DAS with an additional control for observation with cv. Dharani (TCGS-1043) variety. Result: The application of cycocel @ 1000 ppm recorded lowest plant height with maximum no. of primary branches and leaves /plant compared to other growth regulators and control. All physiological parameters studied in the experiment were maximum under foliar spray with CCC @ 1000 ppm. The scheduled application of growth regulators at 30 and 50 DAS decreased plant height, increased branches and leaves/plant significantly at different growth stages and also all physiological parameters compared to single 30 DAS and 50 DAS.
Sosio-Religious Aspects of the Sasak Community in Reading a Puspakarma Manuscript: Islamic Community Development Perspective
Authors: Rahmawati Pudji , Muchammadun Muchammadun , A’yun Ariza Qurrata , Firdaus M. Zainul 
Published: January 2025

There has been intense debate over whether local practices and social engagement effectively contribute to da’wah and participatory community development. Referring to the study of a Puspakarma manuscript from Lombok, coded Gallery-50B Ciputat, the paper sheds light on the local socio-religious values that form the collective memory of Muslim Sasak communities on the island. It further argues that these values offer potential for participatory socio-religious development. The broader context of Sasak culture, as evident in the nineteenth-century Puspakarma text, provides a wider umbrella for the interpretation of elements of the manuscript’s content and message. Data analysis employs Mead’s Symbolic Interactionalism using a person-in-environment model from the perspective of Islamic Community Development. The main findings of the study are that the collective memory of ethnic Sasak Muslims recognizes the supreme being, God, and cooperative social interactions as key to community harmony, just as respect for the ancestors and nature also ensures happiness. All of these views influence community well-being. Furthermore, the author’s analysis demonstrates that each of these components found in the Sasak environment shapes the growth and development of the individual and their worldviews. This research offers fresh insight into how local development may contribute to closing the gap between cross-cultural policy and practice in Lombok and elsewhere.
State-Level Influenza Hospitalization Burden in the United States, 2022–2023
Authors: Couture Alexia , Iuliano A. Danielle , Chang Howard H. , Threlkel Ryan , Gilmer Matthew , O’Halloran Alissa , Ujamaa Dawud , Biggerstaff Matthew , Reed Carrie 
Published: January 2025

Objectives. To develop a method leveraging hospital-based surveillance to estimate influenza-related hospitalizations by state, age, and month as a means of enhancing current US influenza burden estimation efforts. Methods. Using data from the Influenza Hospitalization Surveillance Network (FluSurv-NET), we extrapolated monthly FluSurv-NET hospitalization rates after adjusting for testing practices and diagnostic test sensitivities to non-FluSurv-NET states. We used a Poisson zero-inflated model with an overdispersion parameter within the Bayesian hierarchical framework and accounted for uncertainty and variability between states and across time. Model validation included checking the sensitivity of results to input data, as well as model convergence diagnostics and comparing the results with independent data sources. Results. We estimated 379 300 (90% credible interval [CrI] = 305 400, 479 300) influenza-related hospitalizations in the United States for the 2022–2023 season. Median cumulative state rates ranged widely from 23.2 to 249.0 per 100 000 people. Conclusions. Our estimates were comparable to national burden estimates incorporating other approaches while accounting for variations in the timing and geography of disease activity and changes in detection and reporting. Our results provide a complementary framework to calculate estimates at finer geographic scales. ( Am J Public Health. Published online ahead of print January 30, 2025:e1–e9. https://doi.org/10.2105/AJPH.2024.307928 )
Syndromic Surveillance and Case Identification for Varicella Among Recent Immigrants: New York City, 2023
Authors: Askari Melanie S. , Arciuolo Robert J. , Matalka Olivia , Graham Krishika A. , Isaac Beth M. , Lall Ramona , Jean Antonine , Rosen Jennifer B. 
Published: January 2025

Objectives. To determine utility of syndromic surveillance in improving varicella case detection during an outbreak among recent immigrants to New York City (NYC). Methods. During March through August 2023, the NYC Health Department received varicella reports from routine sources and syndromic surveillance from emergency department visits with varicella as a chief complaint or discharge diagnosis. Reports were reviewed to determine if individuals met criteria for confirmed or probable varicella cases and if cases were outbreak-associated. We calculated positive predictive value (PPV) and timeliness of syndromic surveillance reports and compared them with routine surveillance reports. Results. The health department received 639 unique varicella reports. Of 513 varicella cases, 247 (48.1%) were from syndromic surveillance alone, 194 (37.8%) from routine sources alone, and 72 (14.0%) from both sources. PPV was higher for syndromic surveillance (89.1%) versus routine surveillance (74.7%). Among 310 outbreak-associated cases, 139 were identified through syndromic surveillance (44.8%); syndromic surveillance was the only reporting source for 75 (24.2%). Syndromic surveillance was more timely than routine reporting (median = 3 days; range = 1–27 vs 5 days; range = 0–52). Conclusions. NYC syndromic surveillance improved varicella case detection during this outbreak. ( Am J Public Health. Published online ahead of print January 30, 2025:e1–e4. https://doi.org/10.2105/AJPH.2024.307961 )
Study of Sodium Benzoat, Cyclamate , Dissolved solids and Water Content on Commercial Product of Jam in Surabaya Region
Authors: Aprilianto Richardus , Rahmiati Retnani , Handarini Kejora 
Published: January 2025

Jam is a processed food in a gel or semi solid food from fruit pulp with sugar, acid and food additives. Use of food additives with maximum threshold will effect in our body health. Beside of food additives, physical quality characteristics are also important to making the jam. The purpose of this study was to determine value of sodium benzoat, cyclamate, dossolved solids and water content based on merk and various commersial product of jam in Surabaya region. The research method was a descriptive observations with a total of 21 sample tested. The data in this study were analyzed descriptively and inferential statistics. From the research results, were obtained that 14,8% sample exceeds the threshold of sodium benzoat regulation, 61.9% had a little high water content, all of sample followed the regulation in cyclamate threshold and dissolved solids. The result show value of cyclamate was inversely proportional to dissolved solids. Differences in different brands and variants was not significant in the test results of sodium benzoat, cyclamate and water content. While in dissolved solids the brands provided significant different.
Comparison of sperm activity indices in the experimental model of healthy male BALB/C mice and subacute bisphenol A (Bpa) poisoning
Authors: Ganjavar Homayoun , Mohammadsadegh Majid , Almousavi Saber 
Published: January 2025

Abstract

Endocrine disrupting chemicals or xenoestrogens are natural or synthetic compounds that have the ability to disrupt the endocrine system by mimicking or blocking endogenous hormones. Therefore, the aim of the present study was to compare sperm activity indices in the experimental model of healthy male BALB/C mice and subacute bisphenol A (Bpa) poisoning. For this purpose, 30 mice were purchased and divided into 5 groups of 6 for testing. The rats in the first group were negative control , second group received propylene glycol as vehicle control and in the following groups received different doses of bisphenol A (from 50 mg/kg/daily to 600 mg/kg/daily) . Then, the sperms were sampled and the quality indicators of the sperms such as percentage of motility, viability, etc. were evaluated. Finally, using statistical methods, the results obtained in the present study were statistically analyzed. The average indices of concentration (p=0.001), motility and amount of progressive sperm (p=0.003), amount of motile sperm (p=0.001), live sperm (p=0.0001) and sperm with normal morphology (p=0.003) in the receiving groups Bisphenol A was significantly reduced. The study shows that , the chemical bisphenol A has a very destructive effect on sperm and effectively causes infertility.
Pharmacological Activation of SIRT6 Suppresses Progression of Head and Neck and Esophagus Squamous Cell Carcinoma by Modulation of Cellular Metabolism and Protein Translation
Authors: Elkabets Moshe , Lulu Talal Ben , Pevzner Yaniv , Sklarz Menachem , Mathukkada Sooraj , Marripati Divyasree , Shimshilashvili-Kleiner Liana , Ohana Ehud , Cohen Idan , Zhang Jian , Rotblat Barak , Hai Wang , Kong Dexin , Cohen Ofir , Toiber Debra 
Published: January 2025

Abstract

Sirtuin 6 (SIRT6), a NAD+ -dependent histone deacetylase, has been shown to function as a tumor suppressor gene in several cancer types, including in squamous cell carcinoma of the head and neck and esophagus (HNSCC and ESCC). However, the potential of therapies involving the activation of SIRT6 in HNSCC and ESCC remains unexplored. In this work, we investigated the therapeutic potential and mechanisms of action of the allosteric SIRT6 activator MDL-800 in HNSCC and ESCC cell lines both in vitro and in vivo. First, we showed that MDL-800 treatment exhibited extensive anti-tumor activity in vitro by inhibiting the proliferation and migration of HNSCC and ESCC cell lines. In cell-derived xenograft mouse models, MDL-800 treatment effectively delayed tumor growth in two cancer models. Mechanistically, using global H3K9ac acetylation profiling, and protein arrays, we demonstrated that MDL-800 treatment potently inhibits glucose metabolism, and protein translation induced by impeded mTOR, E2F-related G1/S transcription, ribosomal protein S6 (S6) and, 4E-BP1 activity. This inhibition of mTOR induces a feedback loop involving IGF-1R/INSR activation, which subsequently enables glucose uptake into the cell. IGF1R activation limited the anti-tumor activity of MDL-800 as the PI3K/AKT pathway became hyperactive. Preventing this feedback loop using alpha-specific PI3K inhibitor (BYL719/Alpelisib) resulted in a synergistic anti-tumor effect when MDL-800 and BYL719 were combined. In vivo, the combined treatment of MDL-800 and BYL719 resulted in a prolonged response, with minimal progression observed even 30 days post-initial treatment. Overall, our study identified the molecular mechanisms underlying SIRT6 activation in HNSCC and ESCC. Our findings indicate that SIRT6 activators may have therapeutic potential, either alone or in combination with PI3K inhibition in cancers where SIRT6 is downregulated and serves as a tumor suppressor.
Unlocking Foreign Language Enjoyment in GenAI-Assisted English Learning: A Q-Methodology Perspective from Chinese EFL Students
Authors: Gao Yang , Quan Quan 
Published: January 2025

Abstract

This study employs Q methodology to investigate Chinese EFL students' foreign language enjoyment in GenAI-assisted English learning environments. Through Q-sorting and follow-up written responses from university students, this research identified three distinct patterns: (1) Instrumental Support Orientation, characterized by enjoyment derived from GenAI's immediate assistance and error correction features, but showing limited engagement with deeper learning processes; (2) Independent Learning Achievement, reflecting high satisfaction from autonomous goal attainment and learning efficiency while demonstrating resistance to peer interaction and collaborative learning; and (3) Learning Feature Exploration, emphasizing enjoyment through experimenting with various GenAI functionalities but expressing significant skepticism about language learning outcomes and anxiety reduction. These findings extend our understanding of FLE in technology-enhanced language learning by revealing how learners experience enjoyment through different pathways of GenAI interaction.
Predictability of Obesity and Metabolic Syndrome by Neck Circumference in Nigerian Adolescents with Obesity.
Authors: Bamigboye-Taiwo Olukemi T. , Afolabi Samson , Ajose Olabamiji Abiodun , Ogunlade O 
Published: January 2025

Abstract

Background
Metabolic syndrome is a rapidly emerging global health challenge characterized cardiometabolic risk factors that increase the likelihood of developing cardiovascular disease and type 2 diabetes. While manifesting majorly in adults, evidence suggests these risk factors emerge in childhood. Neck circumference, has shown promise as a simple, inexpensive, and non-invasive screening tool for obesity and related risks in adolescents, though its relationship with metabolic syndrome risk factors remains unclear.
Objectives
To evaluate the association of neck circumference (NC) with obesity and cardio-metabolic risk factors in Nigerian adolescents with and without obesity.
Methods
A study was conducted among 250 adolescents aged 10 to 19 years (125 with obesity and 125 without). Anthropometric parameters, blood pressure and pulse rate were measured. Venous samples were obtained for fasting plasma lipids [Total cholesterol (TC), high density lipoprotein – cholesterol (HDL-C), low density lipoprotein – cholesterol (LDL-C), Triglycerides (TG)] and fasting plasma glucose (FPG) estimation.
Results
There were 24 (19.2%) males and 101 (80.8%) females in each group, giving a male to female ratio of 1: 4.2. Median (SD) age for the adolescents with and without obesity was 15.69 (2.24) and 15.74 (2.25) years respectively. Neck circumference correlated positively with weight (r = 0.265, p = 0.003), height (r = 0.222, p = 0.013), and BMI (r = 0.209, p = 0.019) but not with waist circumference (r = 0.167, p = 0.063) in adolescents with obesity. There was no relationship between neck circumference and TC, HDL-C, LDL-C, TG, or FPG in either of the two groups of adolescents.
Conclusions
From this study, neck circumference can predict obesity but not central obesity and other cardiometabolic risks in Nigerian adolescents.
Kinetic Analysis of Reduction Reaction of MnO from High Carbon Ferromanganese Slag using Fractional Differential Equations (FDE)
Authors: UnDok Kim , MyongJae Kim , IlChol Ju 
Published: January 2025

Abstract

In this paper, a kinetic model for the reduction process by solid carbon of MnO in high-carbon ferromanganese slags using fractional differential equations(FDE) was developed, the relationship between fractional order, fractional rate constant and temperature was determined, and the accuracy of the fractional order model was verified. The fractional order q is 0.892, 0.808, and 0.522, at 1,450 ℃, 1,500 ℃, and 1,600 ℃respectively, and the fractional rate constant kq 1.176E-03, 2.856E-03, and 3.477E-02. A linear relationship exists between the fractional order and the temperature, and an exponential relationship exists with the fractional rate constant. Comparing the conversion factors calculated from the FDE and previous model with the experimental values, the RMSE were 0.005 and 0.029, respectively, and the r2 0.999 and 0.980. This means the FDE model is more accurate. The apparent activation energy of the MnO reduction process calculated using the model was 181.1 kJ/mol.