bluuebunny/crossref_metadata_2025_split huggingface dataset:
Robert Wight names and types in Pouzolzia (Urticaceae) published in Icones plantarum Indiae orientalis
Authors: Jeomol K.K. , Sunojkumar P. 
Published: October 2023

AbstractLectotypes are designated for 34 previously untypified names in the genus Pouzolzia belonging to the family Urticaceae published by Robert Wight in Icones plantarum Indiae orientalis, as a part of taxonomic studies of the family Urticaceae in India. Lectotypes are designated for the following names: Pouzolzia acuta, P. ambigua, P. angustifolia, P. aspera, P. auriculata, P. bennettiana, P. bicuspidata, P. concinna, P. courtallensis, P. cymosa, P. elliptica, P. gardneriana, P. glabra, P. heterocarpa, P. johnsoniana, P. longifolia, P. neilgherrensis, P. oblongifolia, P. ovalifolia, P. ovata, P. parvifolia, P. pilosa, P. procumbens, P. pyramidata, P. rheedei, P. rostrata, P. rotundifolia, P. scabra, P. scabrida, P. stocksii, P. tetraptera, P. tomentosa, P. walkeriana, and P. wallichiana. Pouzolzia microphylla is reassigned as a synonym of P. zeylanica. In addition, two names of Roxburgh (Urtica tuberosa, U. vesicaria) published in Flora Indica that are basionyms of Wight's combinations are also lectotypified.
Ecologies of Conflict and Coexistence in the Mediterranean: Seeking Refuge in post-war Lebanon
Authors: Fakhoury Tamirace , Aitken Miriam 
Published: October 2023

AbstractThis chapter draws on the example of refugee displacement in Lebanon to derive broader conceptions on how notions of national identity and otherness materialize, interlace, and collide in the Mediterranean. We argue that Lebanon’s political system has constructed the figure of the refugee as a disrupter to Lebanon’s national identity, framed in the political rhetoric as a static bond structuring relationships between already existing sectarian communities. This bond revolves around a century-old sectarian power-sharing formula in which eighteen confessions are supposed to divide political offices and resources. At the same time, refugee-centric spaces have contested such ossified conceptions of identity. Civic and humanitarian actors have curated alternative spaces of hospitality. Moreover, contentious episodes including Lebanon’s 2019 iconic protest movement as well as smaller-scale refugee-led protests have called for debunking the conception of a closed, exclusionary, and sectarian-tied citizenship. In broader perspective, we draw attention to how the politics of refuge unlocks a heterotopic space where conflict and coexistence as well as exclusion and inclusion co-constitute each other, and where static and dynamic conceptions of citizenship interlace.
The Institutional Channeling of Transnational Economic Mobilization in Three Moroccan Regions
Authors: Bousetta Hassan , Jamid Hicham , Oubad Ismaïl 
Published: October 2023

AbstractThis chapter analyses the interaction between transnational economic mobilization between Europe and Morocco, on the one hand, and diaspora policies deployed in Morocco on the other hand. The objective is to better understand how transnational economic exchanges contribute to redefining the links between home societies and emigrant communities while at the same time redefining the latter as diasporas. These processes lie at the crossroads of new migration dynamics, new modes of economic action among emigrant communities and new State responses to these demands. Dwelling on the authors’ previous research on Moroccans in Europe and on a new project conducted in three Moroccan administrative regions (Oriental, Beni-Mellal-Khenifra and Souss Massa), the paper looks more particularly at how diaspora policies are being formulated at sub-state level and thus providing insights into how the transnational economic mobilization of Moroccan diasporic entrepreneurs is institutionally channeled.
Transnational Migrant Entrepreneurship Policies in the Maghreb Countries: Tunisia, Algeria, and Morocco
Authors: Djelti Samir , Zapata-Barrero Ricard 
Published: October 2023

AbstractThis chapter explores how the economic context shapes the Transnational Migrant Entrepreneurship’s (TME) Policies in three different migratory regimes: Tunisia, Algeria, and Morocco. First, the theoretical background, linking the traditional migration and development debate with a more recent discussion linking migration, transnationalism, and entrepreneurship is reviewed. Second, the influence of the economic context on governments’ to adopt TME’s policies is analyzed. Findings have shown that Tunisia has adopted a step-by-step entrepreneurship migration policy building, Algeria has taken a two-in-one entrepreneurship policy for nationals and bi-nationals, and Morocco has chosen to trigger two parallel entrepreneurship policies for both nationals and their migrants living abroad. The discussion of these outcomes has concluded that the interrelation between the economic context and the political realm drive new patterns of TME’s policies in the three Maghreb countries. These findings open a theoretical debate on how the traditional migration/development discussion draws new understandings on the Global South and Global North relations.
The Migration Initiatives encouraged by the Local and Regional Networks and their effects in the Euromed Cooperation
Authors: Solduga Gemma Aubarell 
Published: October 2023

AbstractSince the migration and refugee crisis of 2015, local and regional authorities (LRA) are networking to increase their incidence in the migratory policy-making. Still, it is not clear if these collaborative platforms are having a concrete impact in terms of external migratory policies with a Mediterranean regional view. To contribute to this analysis, this study presents a policy framework, based on six outstanding migration initiatives led by selected local regional networks (LRN). The objective is to identify the effects of this cooperative relation in terms of transnational policies in the euro-Mediterranean context for the period 2015–2021. The first part of the article displays the European migratory priorities in the region involving LRA. The second identifies the outstanding initiatives led by some LRN and develops a frame policy analysis accordingly. This section outlines the challenge of sustainability; the limits of multilevel governance and the absence of southern Mediterranean engagement. The multi-sectoral approach, which makes use of decentralized institutions and programs, has become a new tool for these emerging lobbies. The third part addresses the narrative of these networks when it comes to migration confirming the existence of a building Mediterranean focus of interest of the LRN.
Results
Authors: Pedersen Mette 
Published: October 2023

AbstractKnowledge about the changes of the vocal folds during puberty in children has been focused upon in many cases. Döllinger et al. write that children demonstrate greater cycle-to-cycle variability in oscillations compared to adults [1]. Based on videokymography and high-speed videos, Cavalli et al. suggest changes of treatment of pediatric voice disorders because there are important differences between the developmental approach and disorders for surgical and therapeutic management [2]. As late as 2012, an evaluation of pathology was made by Martins et al. of 304 children from 4 to 18 years where the findings related to normal pubertal development were not commented on [3].
Cyclic Shuffle-Compatibility Via Cyclic Shuffle Algebras
Authors: Liang Jinting , Sagan Bruce E. , Zhuang Yan 
Published: October 2023

AbstractA permutation statistic $${{\,\textrm{st}\,}}$$

st

is said to be shuffle-compatible if the distribution of $${{\,\textrm{st}\,}}$$

st

over the set of shuffles of two disjoint permutations $$\pi $$
π
and $$\sigma $$
σ
depends only on $${{\,\textrm{st}\,}}\pi $$

st

π

, $${{\,\textrm{st}\,}}\sigma $$

st

σ

, and the lengths of $$\pi $$
π
and $$\sigma $$
σ
. Shuffle-compatibility is implicit in Stanley’s early work on P-partitions, and was first explicitly studied by Gessel and Zhuang, who developed an algebraic framework for shuffle-compatibility centered around their notion of the shuffle algebra of a shuffle-compatible statistic. For a family of statistics called descent statistics, these shuffle algebras are isomorphic to quotients of the algebra of quasisymmetric functions. Recently, Domagalski, Liang, Minnich, Sagan, Schmidt, and Sietsema defined a version of shuffle-compatibility for statistics on cyclic permutations, and studied cyclic shuffle-compatibility through purely combinatorial means. In this paper, we define the cyclic shuffle algebra of a cyclic shuffle-compatible statistic, and develop an algebraic framework for cyclic shuffle-compatibility in which the role of quasisymmetric functions is replaced by the cyclic quasisymmetric functions recently introduced by Adin, Gessel, Reiner, and Roichman. We use our theory to provide explicit descriptions for the cyclic shuffle algebras of various cyclic permutation statistics, which in turn gives algebraic proofs for their cyclic shuffle-compatibility.
Effects of a dissociative drug on fronto-limbic resting-state functional connectivity in individuals with posttraumatic stress disorder: a randomized controlled pilot study
Authors: Danböck Sarah K. , Duek Or , Ben-Zion Ziv , Korem Nachshon , Amen Shelley L. , Kelmendi Ben , Wilhelm Frank H. , Levy Ifat , Harpaz-Rotem Ilan 
Published: October 2023

Abstract
Rationale
A subanesthetic dose of ketamine, a non-competitive N-methyl-D-aspartate glutamate receptor (NMDAR) antagonist, elicits dissociation in individuals with posttraumatic stress disorder (PTSD), who also often suffer from chronic dissociative symptoms in daily life. These debilitating symptoms have not only been linked to worse PTSD trajectories, but also to increased resting-state functional connectivity (RSFC) between medial prefrontal cortex (mPFC) and amygdala, supporting the conceptualization of dissociation as emotion overmodulation. Yet, as studies were observational, causal evidence is lacking.

Objectives
The present randomized controlled pilot study examines the effect of ketamine, a dissociative drug, on RSFC between mPFC subregions and amygdala in individuals with PTSD.

Methods
Twenty-six individuals with PTSD received either ketamine (0.5mg/kg; n = 12) or the control drug midazolam (0.045mg/kg; n = 14) during functional magnetic resonance imaging (fMRI). RSFC between amygdala and mPFC subregions, i.e., ventromedial PFC (vmPFC), dorsomedial PFC (dmPFC) and anterior-medial PFC (amPFC), was assessed at baseline and during intravenous drug infusion.

Results
Contrary to pre-registered predictions, ketamine did not promote a greater increase in RSFC between amygdala and mPFC subregions from baseline to infusion compared to midazolam. Instead, ketamine elicited a stronger transient decrease in vmPFC-amygdala RSFC compared to midazolam.

Conclusions
A dissociative drug did not increase fronto-limbic RSFC in individuals with PTSD. These preliminary experimental findings contrast with prior correlative findings and call for further exploration and, potentially, a more differentiated view on the neurobiological underpinning of dissociative phenomena in PTSD.
Purebred dogs show higher levels of genomic damage compared to mixed breed dogs
Authors: Santovito Alfredo , Saracco Martina , Scarfo’ Manuel , Nota Alessandro , Bertolino Sandro 
Published: October 2023

AbstractInbreeding is a common phenomenon in small, fragmented or isolated populations, typical conditions of many threatened species. In the present paper, we used a new non-invasive approach based on the buccal micronucleus assay to evaluate the possible relationships between inbreeding and genomic damage using the dog as model species. In particular, we assessed the frequencies of micronuclei and other nuclear aberrations in a group of purebred dogs (n = 77), comparing the obtained data with those from a control group represented by mixed breed dogs (n = 75). We found a significant increase of micronuclei, nuclear buds and total nuclear aberrations frequencies in purebred dogs compared to mixed-bred dogs. The absence of significant differences in the frequency of micronuclei and other nuclear aberrations amongst different breeds reinforces the hypothesis that the observed increased genomic damage amongst purebred dogs may not be due to a different genomic instability typical of a particular breed, but to inbreeding itself. This hypothesis is further confirmed by the fact that other endogen confounding factors, such as sex, age and weight, do not contribute significantly to the increase of genomic damage observed amongst purebred dogs. In conclusion, results presented in this study showed that, in purebred dogs, inbreeding may increase the levels of genomic damage. Considering that genomic damage is associated with increased physiological problems affecting animal health, the results we obtained may represent a stimulus to discourage the use of intensive inbreeding practices in captive populations and to reduce the fragmentation of wild populations.
Trends in ocean waves climate within the Mediterranean Sea: a review
Authors: De Leo Francesco , Briganti Riccardo , Besio Giovanni 
Published: October 2023

AbstractThe interest for the impact of climate change on ocean waves within the Mediterranean Sea has motivated a number of studies aimed at identifying trends in sea states parameters from historical multi-decadal wave records. In the last two decades progress in computing and the availability of suitable time series from observations further supported research on this topic. With the aim of identifying consensus among previous research on the Mediterranean Sea and its sub-basins, this review analysed the results presented in peer reviewed articles researching historical ocean waves trends published after the year 2000. Most studies focused on the significant wave height trends, while direction and wave period appear to be under-studied in this context. We analysed trends in mean wave climate and extreme sea states. We divided the Mediterranean basin in 12 sub-basins and analysed the results available in the literature from a wide range of data sources, such as satellite altimetry and numerical models, among others. The consensus on the significant wave height mean climate trends is limited, while statistically significant trends in extreme values are detected in the western Mediterranean Sea, in particular in the Gulf of Lion and in the Tyrrhenian Sea, with complex spatial distributions. Negative extreme sea state trends in the sub-basins, although frequently identified, are mostly not significant. We discuss the sources of uncertainty in results introduced by the data used, statistics employed to characterise mean or extreme conditions, length of the time period used for the analysis, and thresholds used to prove trends statistical significance. The reduction of such uncertainties, and the relationship between trends in sea states and weather processes are identified as priority for future research.
Expanding the scope of methylation-sensitive restriction enzyme (MSRE) PCR for forensic identification of body fluids through the novel use of methylation-dependent restriction enzymes (MDRE) and the combination of autosomal and Y-chromosomal markers
Authors: Rothe Jessica , Becker Jessica Maria , Charchinezhadamouei Maral , Mähr Sophia , Lembeck Felizitas , Dannemann Nora , Nagy Marion 
Published: October 2023

AbstractMethylation-sensitive/-dependent restriction enzyme (MSRE/MDRE) PCR can be performed to detect hypomethylated or hypermethylated CpG sites. With the combined use of different tissue-specific CpG markers, MSRE/MDRE-PCR leads to tissue-specific methylation patterns (TSMPs), enabling the correlation of DNA samples to their source tissue. MSRE/MDRE assays can use the same platform as forensic STR typing and offer many advantages in the field of forensic body fluid detection. In the present study, we aimed to establish MSRE assays for the detection of blood, saliva, vaginal secretion, and semen, using markers from literature and from our own database search. We designed two different MSRE test-sets, which include two novel Y-chromosomal non-semen markers, and enable differentiation between female and male non-semen samples. Furthermore, we established an MSRE/MDRE semen approach, which includes only Y-chromosomal non-semen and semen markers. This Y-semen multiplex PCR utilizes the novel combination of the methylation-sensitive enzyme SmaI and the methylation-dependent enzyme GlaI, which enables more sensitive detection of male body fluids within male/female DNA mixtures. Our validation tests confirmed that MSRE/MDRE assays exhibit high sensitivity, similar to that of STR typing.
Identification and management of subclinical disease activity in early multiple sclerosis: a review
Authors: Ontaneda Daniel , Chitnis Tanuja , Rammohan Kottil , Obeidat Ahmed Z. 
Published: October 2023

Abstract
Importance
Early treatment initiation in multiple sclerosis (MS) is crucial in preventing irreversible neurological damage and disability progression. The current assessment of disease activity relies on relapse rates and magnetic resonance imaging (MRI) lesion activity, but inclusion of other early, often “hidden,” indicators of disease activity may describe a more comprehensive picture of MS.

Observations
Early indicators of MS disease activity other than relapses and MRI activity, such as cognitive impairment, brain atrophy, and fatigue, are not typically captured by routine disease monitoring. Furthermore, silent progression (neurological decline not clearly captured by standard methods) may occur undetected by relapse and MRI lesion activity monitoring. Consequently, patients considered to have no disease activity actually may have worsening disease, suggesting a need to revise MS management strategies with respect to timely initiation and escalation of disease-modifying therapy (DMT). Traditionally, first-line MS treatment starts with low- or moderate-efficacy therapies, before escalating to high-efficacy therapies (HETs) after evidence of breakthrough disease activity. However, multiple observational studies have shown that early initiation of HETs can prevent or reduce disability progression. Ongoing randomized clinical trials are comparing escalation and early HET approaches.

Conclusions and relevance
There is an urgent need to reassess how MS disease activity and worsening are measured. A greater awareness of “hidden” indicators, potentially combined with biomarkers to reveal silent disease activity and neurodegeneration underlying MS, would provide a more complete picture of MS and allow for timely therapeutic intervention with HET or switching DMTs to address suboptimal treatment responses.
Validation of Modaplex POLE mutation assay in endometrial carcinoma
Authors: Dorca Eduard , Velasco Ana , Varela Mar , Gatius Sonia , Villatoro Sergio , Fullana Neus , Cuevas Dolors , Vaquero Marta , Birnbaum Astrid , Neumann Karsten , Matias-Guiu Xavier 
Published: October 2023

AbstractThe TCGA-based molecular classification of endometrial cancer has emerged as an important tool to stratify patients according to prognosis. A simplified scheme has been proposed, by using immunohistochemistry for p53, MSH6, and PMS2 and a molecular test for POLE mutations (NGS or Sanger sequencing, techniques that are not available in many centers worldwide). In this study, we validate a novel method that allows simultaneous analysis of multiple pathogenic POLE mutations. The Modaplex technology integrates polymerase chain reaction and capillary electrophoresis. The design of this study encompassed 4 different steps: (1) a retrospective-pilot phase, with 80 tumors, balancing the four molecular subgroups. (2) A retrospective phase of 25 tumors obtained between 2016 and 2020, and 30 tumors obtained between 2000 and 2015. (3) An inter-laboratory corssavalidation step with 19 cases (belonging to phases 1 and 2). (4) A prospective cohort of 123 tumors, of unknown POLE status, with simultaneous validation by Sanger sequencing. A total of 258 samples were analyzed. In the first and second phases, the test showed positive/negative predictive values of 100%, by correctly identifying POLE mutation status in 79/79 and 55/55 cases. Phase 3 showed 100% of inter-laboratory consistency. Phase 4 showed 16 positive samples out of the 123 prospective cases. Overall, the test has revealed sensitivity and specificity of 100%, identifying a total of 47 POLE-mutated tumors. We have shown that this technique allows faster and easier identification of multiple pathogenic POLE mutations with high robustness and confidence when comparing to other tests such as Sanger sequencing.
Near-infrared fluorescence tattooing: a new approach for endoscopic marking of tumors in minimally invasive colorectal surgery using a persistent near-infrared marker
Authors: Thomaschewski Michael , Lipp Michael , Engelke Carsten , Harder Jonas , Labod Isabell , Keck Tobias , Mittmann Karin 
Published: October 2023

Abstract
Introduction
Intraoperative accurate localization of tumors in the lower gastrointestinal tract is essential to ensure oncologic radicality. In minimally invasive colon surgery, tactile identification of tumors is challenging due to diminished or absent haptics. In clinical practice, preoperative endoscopic application of a blue dye (ink) to the tumor site has become the standard for marking and identification of tumors in the colon. However, this method has the major limitation that accidental intraperitoneal spillage of the dye can significantly complicate the identification of anatomical structures and surgical planes. In this work, we describe a new approach of NIR fluorescent tattooing using a near-infrared (NIR) fluorescent marker instead of a blue dye (ink) for endoscopic tattooing.

Methods
AFS81x is a newly developed NIR fluorescent marker. In an experimental study with four domestic pigs, the newly developed NIR fluorescent marker (AFS81x) was used for endoscopic tattooing of the colon. 7–12 endoscopic submucosal injections of AFS81x were placed per animal in the colon. On day 0, day 1, and day 10 after endoscopic tattooing with AFS81x, the visualization of the fluorescent markings in the colon was evaluated during laparoscopic surgery by two surgeons and photographically documented.

Results
The detection rate of the NIR fluorescent tattoos at day 0, day 1, and day 10 after endoscopic tattooing was 100%. Recognizability of anatomical structures during laparoscopy was not affected in any of the markings, as the markings were not visible in the white light channel of the laparoscope, but only in the NIR channel or in the overlay of the white light and the NIR channel of the laparoscope. The brightness, the sharpness, and size of the endoscopic tattoos did not change significantly on day 1 and day 10, but remained almost identical compared to day 0.

Conclusion
The new approach of endoscopic NIR fluorescence tattooing using the newly developed NIR fluorescence marker AFS81x enables stable marking of colonic sites over a long period of at least 10 days without compromising the recognizability of anatomical structures and surgical planes in any way.