bluuebunny/crossref_metadata_2025_split huggingface dataset:
La desprovincialización del conocimiento comentario del libro
Authors: Zarria Santiago M. 
Published: January 2024

El libro de Burke se sitúa entre «la historia de las diásporas y la historia del conocimiento».
El exiliado académico del que habla Burke es el portador de un conocimiento que ha debido desplazar, trasplantar y traducir en otro lugar y en este proceso de transterramiento, algunos han fracasado y otros han sido exitosos. La creación y la contribución del conocimiento surgen así de intelectuales que se ubicaron entre la asimilación y la auto-marginación.
Este comentario subraya, que, el autor, pese a que su abordaje pretende ser global, deja de lado un análisis apropiado al caso latinoamericano que permite dar cuenta de la desprovincialización e hibridación del conocimiento.
Responsabilidad penal del empresario
Authors: Ponce Gabriel 
Published: January 2024

El avance de la sociedad exige que el Derecho esté a la par de su desarrollo, y el Derecho Penal no puede ser una excepción. Por este motivo, ya no se limita al estudio de los delitos tradicionales, sino que se ha extendido a estudiar los delitos relacionados con la actividad empresarial y la responsabilidad de los empresarios.
Con la teoría de la imputación objetiva, la solución al problema de la criminalidad empresarial empieza a tomar forma bajo principios como el deber objetivo de cuidado o el de confianza, que justifican su aplicación contra el actuar ilícito del empresario, donde las tesis de la autoría y participación buscan un espacio fuera de las teorías clásicas para calar dentro de la estructura empresarial y sancionar a los responsables de los hechos ilícitos cometidos a través de la empresa.
Uno de los mecanismos para prevención de delitos, y que llega a ser una exigencia para la sociedad actual, es la aplicación de las normas de compliance, que buscan la auto regulación de la compañía, mediante la aplicación de sus propias sanciones contra quienes actúen fuera del marco legal; y/o, para facilitar la identificación de los responsables de conductas ilícitas realizadas a través de la empresa, un procedimiento que va de la mano con la teoría de la imputación objetiva.
Jorge Castellanos Claramunt: La participación ciudadana en el ámbito local. La integración democrática de lo local y de lo global en la era digital
Authors: Imormino De Haro María Guadalupe 
Published: January 2024

Recensión del libro de Jorge Castellanos Claramunt: La participación ciudadana en el ámbito local. La integración democrática de lo local y de lo global en la era digital, Valencia, Corts Valencianes, 2020.
Impact of Various Land Use Systems on Nitrogen Dynamics: A Review
Authors: Biradar Sayali , Thakare Ritu , Kamble B. M. 
Published: January 2024

Rapid and unregulated conversion of agricultural fields into non-agricultural lands is becoming a major concern in many countries. The shortage of cultivable lands will make it harder to achieve ever-increasing food demands in upcoming years. Assessing land use-induced changes in soil nitrogen is essential for addressing agroecosystem transformation and sustainable land productivity issues. Numerous studies have shown that land use pattern has a significant effect on nitrogen storage and turnover along with varied degrees of mineralization rate and nitrogen forms present. The content of nitrogen fraction can be used as an indicator of the rate of mineralization and eventually microbial richness of soils. As per the study, it is observed that inorganic nitrogen fractions constitute hardly 1-2% of total nitrogen, whereas organic nitrogen takes up almost 98-99% of total nitrogen that is majorly sourced from organic residues in soils. The exchangeable NO3-N and exchangeable NH3-N are majorly plant-utilizable, easily mineralized forms whereas only amino acid-N has been proved to be directly utilizable organic nitrogen form. Even today large number of producers are dependent on synthetic nitrogen sources for crop production. Improving nitrogen use efficiency by reducing the natural losses and improving the inherent mineralization rate of organic nitrogen might help lower fertilizer dependency and so the cost of production. In this paper, soil inorganic and organic nitrogen contents, types, and its contribution to plant production are reviewed to explore the exact role of nitrogen forms as influenced under different land use systems.
High Speed Dual‐Band Photodetector for Dual‐Channel Optical Communications in Wavelength Division Multiplexing and Security Enhancement
Authors: Wang Zhaoming , Gao Yu , Li Yibin , Yan Hao , Kang Feiyu , Shen Yang , Zhang Xiao‐Ping , Wei Guodan , Fu Hongyan 
Published: January 2024

AbstractThe forthcoming wireless networks must integrate to a high density of end‐user devices while ensuring a superior quality of service. It is imperative to devise solutions that reduce the density of wireless access points and associated costs, while simultaneously ensuring security and privacy throughout propagation. Herein, a novel dual‐band photodetector with high selective responsivities in distinct visible and near‐infrared (NIR) band is developed as an optical signal receiver. The receiver has an unprecedented fast switch speed > 500 kHz between different operation modes. Leveraging this fast switch speed, a high‐speed Multiple‐Input‐Single‐Output (MISO) system is developed, fusing spectrum resources from visible to infrared bands. The system achieves a data rate of 600 Kbps in the visible channel and 500 Kbps in the NIR channel, with a sum rate of 1.1 Mbps. This is the highest single‐channel data rate and sum rate among reported dual‐band photodetectors. Additionally, two previously overlooked mechanisms, the Subtraction and Addition modes, are studied in detail. The four operation modes are developed to establish a novel physical encryption method in terms of arithmetic relation. The dual‐channel coupled link can support a data rate of 200 Kbps, significantly enhancing communication security.
A Freeze‐Resistant, Highly Stretchable and Biocompatible Organohydrogel for Non‐Delayed Wearable Sensing at Ultralow‐Temperatures
Authors: Huang Xinxin , Zheng Zhihao , Wang Haiqi , Xu Weipeng , Wu Ming , Wang Minyan , Chen Canwen , Wan Lu , Du Ruichun , Zhu Tangsong , Huang Zhiyi , Wang Xiaoliang , Wang Xiaofeng , Zhang Qiuhong , Jia Xudong 
Published: January 2024

AbstractWearable electronics based on conductive hydrogels (CHs) easily suffer from prolonged response times, reduced wearing comfort, shortened service lives, and impaired signal accuracy in cold environments, because conventional CHs tend to freeze at subzero temperatures and lose their flexibility, adhesion, transparency, and conductivity, which will limit their applications in extreme environments. Inspired by the way psychrotolerant creatures and superabsorbent materials interfere with the hydrogen bonding networks of water, a freeze‐resistant conductive organohydrogel (COH) is facilely fabricated. The synergy effect between charged polar terminal groups and a binary solvent system of water–ethylene glycol weakens the hydrogen bonding between water molecules and endows the COH with remarkable freezing tolerance (−78 °C). Additionally, the obtained COH is ultra‐stretchable (≈6185%), tough (9.2 MJ m−3), highly transparent (≈99%), self‐adhesive (10.2–27.8 kPa), and biocompatible. This versatile COH is assembled into a strain sensor and a well‐designed bracelet electrocardiogram sensor. Benefiting from the exceptional low‐temperature tolerance of the prepared COH, these devices exhibit fast response with delay‐free signals even at −40 °C. Overall, this work proposes a strategy to develop multifunctional COHs for supporting human health in cold environments.
Asymmetric Charge Distribution of Active Centers in Small Molecule Quinone Cathode Boosts High‐Energy and High‐Rate Aqueous Zinc‐Organic Batteries
Authors: Li Cuicui , Hu Liang , Ren Xiuyun , Lin Lu , Zhan Changzhen , Weng Qingsong , Sun Xiaoqi , Yu Xiaoliang 
Published: January 2024

AbstractSmall molecule quinone compounds are attractive cathode materials for rechargeable aqueous zinc‐organic batteries (AZOBs) because of their structural diversity and low‐cost merits. Among them, nonpolar quinones are dominant given the relatively low solubilities in aqueous electrolytes. However, their poor electronic conductivity and accumulated Coulombic repulsion lead to underutilized active sites and sluggish redox kinetics. Here, polar 2,6‐dimethoxy‐1,4‐benzoquinone (m‐DMBQ) works as an advanced AZOB cathode with unexpectedly superior performance over the nonpolar isomer of 2,5‐dimethoxy‐1,4‐benzoquinone (p‐DMBQ). The asymmetric charge distribution of active centers in the p−π conjugated backbone of m‐DMBQ induces reduced bandgap with improved electronic conductivity and redox activity, thus achieving a high specific capacity of 312 mAh g−1 approaching the theoretical limit. Additionally, the lowest unoccupied molecular orbital energy level is lowered for an increased average discharge voltage of 0.88 V. Characterizations and computational studies revealed boosted competitiveness of H+ relative to Zn2+ for significantly enhanced charge transfer kinetics and reversibility. As a result, the as‐fabricated AZOB achieves a high energy density of 275 Wh kg−1 based on m‐DMBQ along with high‐rate capability and long‐term cycling stability. This work provides a new molecular engineering strategy through regulating charge distribution symmetry for boosting charge storage in organic cathodes.
Accelerating Hydrogen Desorption of Nickel Molybdenum Cathode via Copper Modulation for Pure‐Water‐Fed Hydroxide Exchange Membrane Electrolyzer
Authors: Yang Shengxiong , Zhang Zheye , Oliveira Alexandra M. , Xi Shibo , Zhiani Mohammad , Zhang Jian , Tu Zhengkai , Xiao Fei , Wang Shuai , Yan Yushan , Xiao Junwu 
Published: January 2024

AbstractThe more sluggish kinetics of hydrogen evolution catalysts in base as compare to that in acid to some degree restricts hydrogen production performance of hydroxide exchange membrane electrolyzers, especially when using earth‐abundant catalysts. Here a ternary nickel–copper–molybdenum hydrogen evolution catalyst is reported that exhibits ≈5 times higher turnover frequency than without copper doping. The X‐ray absorption near‐edge structure and valence band spectrum demonstrate that the light doping of copper into nickel–molybdenum alloy modulates the electronic structure and downshifts the d‐band center, resulting in accelerated hydrogen desorption, as consolidated by H2 temperature programmed desorption and theoretical calculation. An electrolyzer employing this cathode catalyst and a nickel–iron anode, gives a current density of 1.7 A cm−2 at 2.0 V with a pure‐water feed through the anode, which outperforms the 2025 target proposed by the United States Department of Energy, and even is operated continuously for over 1000 h with a decay rate of as low as 0.5 mV h−1. Post‐mortem analysis discloses that hydroxide exchange ionomer migration is one of the key factors affecting long‐term durability. This work demonstrates the feasibility of a low‐cost, water‐fed hydroxide exchange membrane electrolyzer achieving industrial‐level performance and lifetime.
Memristor‐Based Neuromorphic Chips
Authors: Duan Xuegang , Cao Zelin , Gao Kaikai , Yan Wentao , Sun Siyu , Zhou Guangdong , Wu Zhenhua , Ren Fenggang , Sun Bai 
Published: January 2024

AbstractIn the era of information, characterized by an exponential growth in data volume and an escalating level of data abstraction, there has been a substantial focus on brain‐like chips, which are known for their robust processing power and energy‐efficient operation. Memristors are widely acknowledged as the optimal electronic devices for the realization of neuromorphic computing, due to their innate ability to emulate the interconnection and information transfer processes witnessed among neurons. This review paper focuses on memristor‐based neuromorphic chips, which provide an extensive description of the working principle and characteristic features of memristors, along with their applications in the realm of neuromorphic chips. Subsequently, a thorough discussion of the memristor array, which serves as the pivotal component of the neuromorphic chip, as well as an examination of the present mainstream neural networks, is delved. Furthermore, the design of the neuromorphic chip is categorized into three crucial sections, including synapse‐neuron cores, networks on chip (NoC), and neural network design. Finally, the key performance metrics of the chip is highlighted, as well as the key metrics related to the memristor devices are employed to realize both the synaptic and neuronal components.
Wearable Sensors for Breath Monitoring Based on Water‐Based Hexagonal Boron Nitride Inks Made with Supramolecular Functionalization
Authors: Chen Liming , Hu Kui , Lu Mingyang , Chen Ziqi , Chen Xiwen , Zhou Tianqi , Liu Xuqing , Yin Wuliang , Casiraghi Cinzia , Song Xiuju 
Published: January 2024

AbstractWearable humidity sensors are attracting strong attention as they allow for real‐time and continuous monitoring of important physiological information by enabling activity tracking as well as air quality assessment. Amongst 2Dimensional (2D) materials, graphene oxide (GO) is very attractive for humidity sensing due to its tuneable surface chemistry, high surface area, processability in water, and easy integration onto flexible substrates. However, strong hysteresis, low sensitivity, and cross‐sensitivity issues limit the use of GO in practical applications, where continuous monitoring is preferred. Herein, a wearable and wireless impedance‐based humidity sensor made with pyrene‐functionalized hexagonal boron nitride (h‐BN) nanosheets is demonstrated. The device shows enhanced sensitivity towards relative humidity (RH) (>1010 Ohms/%RH in the range from 5% to 100% RH), fast response (0.1 ms), no appreciable hysteresis, and no cross‐sensitivity with temperature in the range of 25–60 °C. The h‐BN‐based sensor is able to monitor the whole breathing cycle process of exhaling and inhaling, hence enabling to record in real‐time the subtlest changes of respiratory signals associated with different daily activities as well as various symptoms of flu, without requiring any direct contact with the individual.
Molecular Engineering of a Spider Silk and Mussel Foot Hybrid Protein Gives a Strong and Tough Biomimetic Adhesive
Authors: Yin Yin , Roas‐Escalona Nelmary , Linder Markus B. 
Published: January 2024

AbstractHigh performance bio‐based materials are an important part of future sustainable technology, and engineered proteins provide excellent possibilities as functional polymers. Adhesives are widely needed for composite materials and biomimetic structures. In biological adhesives, two features have emerged as especially interesting—the role of coacervation and the presence of 3,4‐dihydroxyphenylalanine (DOPA). To study these, protein engineering is used to construct a hybrid silk‐mussel foot protein (mfp) adhesive. Tyr residues in the purified mfp are oxidized to DOPA and an encoded SpyCatcher‐Tag system allowed easy click‐chemistry to couple silk and mfp and to study the parts separately. The combined silk‐mfp protein have a strong tendency to coacervate. DOPA affected the properties of coacervates and increased adhesion by several ways of measuring. In lap shear testing, the combined mfp‐silk protein is superior to any of the components studied separately. Coacervation is suggested to contribute to the adhesion of silk‐mfp, and shows several features suggested to lead to the strength and toughness of natural adhesives. In the lap shear system, coacervation have a stronger overall effect on adhesion than the presence of DOPA. The results show that protein design provides a route toward high performance biosynthetic polymers and future sustainable materials.
Self‐Destructible Electromagnetic Interference Shielding Films
Authors: Zhou Yang , Pan Yamin , Liu Chuntai , Shen Changyu , Liu Xianhu 
Published: January 2024

AbstractIn response to the increasing utilization of communication technology, there is a growing need for electromagnetic interference (EMI) shielding materials to adapt to diverse application scenarios. In this study, the self‐destructible EMI shielding films (SEFs) that possess the unique capability to reduce conductivity and shielding efficiency through temperature elevation are introduced. The SEFs effectively fulfill the requirement of triggering EMI shielding failure under specific conditions, which can be achieved by simply spraying a mixture of thermally expandable microspheres (TEMs), conductive fillers, and resin substrates. The segregated structures resulting from the incorporation of TEMs confer exceptional electrical conductivity and superior EMI shielding performance at low conductive filler content. When the ambient temperature surpasses the glass transition temperature of the TEM shell, the thermally expandable characteristics cause a disruption in the conductive path of the SEFs, leading to a significant decline in shielding effectiveness. Additionally, the SEFs exhibit outstanding Joule heating effects (90 °C) at low voltage (1.5 V) within a brief time frame (10 s). Importantly, when employed as Joule heaters, the SEFs possess an intrinsic safety mechanism that automatically ceases operation in the event of circuit overload, thus minimizing any potential risks.
Antioxidant Activity via Free Radical Scavenging of Pitavastatin and Its Hydroxylated Derivatives: A Quantum Chemical Attempt Aiming to Assist Drug Development
Authors: Bâldea Ioan 
Published: January 2024

AbstractAlthough experiments have long provided empirical evidence that statins can suppress various oxidation pathways, theoretical attempts to quantify the antioxidant activity of statins (read, atorvastatin ATV, the only one studied so far) are not published until last year. Extensive results reported here for pitavastatin (PVT) and derivatives include the thermodynamic antioxidant descriptors (bond dissociation enthalpy [BDE], adiabatic ionization potential [IP], proton dissociation enthalpy [PDE], proton affinity [PA], and electron transfer enthalpy [ETE]) related to the three antioxidant mechanisms (hydrogen atom transfer [HAT], stepwise electron transfer proton transfer [SETPT], sequential proton loss electron transfer [SPLET]). The particular emphasis is on the PVT's hydroxylated derivatives wherein a hydroxy group replaces a hydrogen atom either on the quinoline core (Q‐hydroxylated metabolites) or on the fluorophenyl ring (F‐hydroxylated metabolites). The calculations indicate that both the Q‐ and F‐hydroxylated derivatives possess antioxidant properties superior to the parent PVT molecule. Given the fact that, to the best of the knowledge, no experimental data for the antioxidant potency of PVT and its hydroxylated derivatives exist, this is a theoretical prediction for the validation of which it is aimed hereby to stimulate companion experimental in vivo and in vitro investigations and inspire pharmacologists in further drug developments.
OR11H1 Missense Variant Confers the Susceptibility to Vogt‒Koyanagi‒Harada Disease by Mediating Gadd45g Expression
Authors: Li Xingran , Wang Guoqing , Wang Xiaotang , Li Wanqian , Li Na , Liu Xianyang , Fan Wei , He Siyuan , Han Yue , Su Guannan , Cao Qingfeng , Yang Peizeng , Hou Shengping 
Published: January 2024

AbstractVogt‒Koyanagi‒Harada (VKH) disease is a severe autoimmune disease. Herein, whole‐exome sequencing (WES) study are performed on 2,573 controls and 229 VKH patients with follow‐up next‐generation sequencing (NGS) in a collection of 2,380 controls and 2,278 VKH patients. A rare c.188T>C (p Val63Ala) variant in the olfactory receptor 11H1 (OR11H1) gene is found to be significantly associated with VKH disease (rs71235604, Pcombined = 7.83 × 10−30, odds ratio = 3.12). Functional study showes that OR11H1‐A63 significantly increased inflammatory factors production and exacerbated barrier function damage. Further studies using RNA‐sequencing find that OR11H1‐A63 markedly increased growth arrest and DNA‐damage‐inducible gamma (GADD45G) expression. Moreover, OR11H1‐A63 activates the MAPK and NF‐κB pathways, and accelerates inflammatory cascades. In addition, inhibiting GADD45G alleviates inflammatory factor secretion, likely due to the regulatory effect of GADD45G on the MAPK and NF‐κB pathways. Collectively, this study suggests that the OR11H1‐A63 missense mutation may increase susceptibility to VKH disease in a GADD45G‐dependent manner.
Novel molecular mechanism in Malan syndrome uncovered through genome sequencing reanalysis, exon‐level Array, and RNA sequencing
Authors: Zhao Jian , Longo Nicola , Lewis Robert G. , Nicholas Thomas J. , Boyden Steven E. , Andrews Ashley , Larson Austin ,   Undiagnosed Diseases Network, Bayrak‐Toydemir Pinar , Botto Lorenzo D. , Mao Rong 
Published: January 2024

AbstractThe NFIX gene encodes a DNA‐binding protein belonging to the nuclear factor one (NFI) family of transcription factors. Pathogenic variants of NFIX are associated with two autosomal dominant Mendelian disorders, Malan syndrome (MIM 614753) and Marshall–Smith syndrome (MIM 602535), which are clinically distinct due to different disease‐causing mechanisms. NFIX variants associated with Malan syndrome are missense variants mostly located in exon 2 encoding the N‐terminal DNA binding and dimerization domain or are protein‐truncating variants that trigger nonsense‐mediated mRNA decay (NMD) resulting in NFIX haploinsufficiency. NFIX variants associated with Marshall–Smith syndrome are protein‐truncating and are clustered between exons 6 and 10, including a recurrent Alu‐mediated deletion of exons 6 and 7, which can escape NMD. The more severe phenotype of Marshall–Smith syndrome is likely due to a dominant‐negative effect of these protein‐truncating variants that escape NMD. Here, we report a child with clinical features of Malan syndrome who has a de novo NFIX intragenic duplication. Using genome sequencing, exon‐level microarray analysis, and RNA sequencing, we show that this duplication encompasses exons 6 and 7 and leads to NFIX haploinsufficiency. To our knowledge, this is the first reported case of Malan Syndrome caused by an intragenic NFIX duplication.
Accessing Functionalized Furans from Reacting Enynones and Enynals through Furyl Metal Carbenes
Authors: Cho Ho‐Jun , Kim Ju Hyun 
Published: January 2024

AbstractEnynones and enynals represent donor‐type carbene precursors that efficiently form furyl metal carbenes via a catalytic intramolecular 5‐exo‐dig cyclization and rearrangement cascade, in a 100 % atom‐economical manner, using various metals. These furyl metal carbenes have been successfully utilized in numerous carbene reactions, including metal carbene X−H insertion, cyclopropanations, metathesis, and cross‐coupling, demonstrating a broad reaction scope and efficiency in constructing highly functionalized furans. Recent years have witnessed significant advancements in transformations involving furyl metal carbenes, especially in asymmetric carbene insertion reactions, domino reactions involving zwitterionic intermediates, various rearrangement strategies, and their application in synthesizing functional materials and drug candidates. In this review, we summarize recent progress in furyl metal carbene reactions generated from enynones and enynals, focusing on the synthesis of highly functionalized furans.