bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Primary Health Team in Promoting Mental Health of Adolescent Students: A Systematic Review
Authors: Silva Thiago Nogueira , Tavares Claudia Mara de Melo , Tavares Marilei de Melo , Moccellin Marcia Cristina , Rebello Marcelle Ignacio , Vargas Fabiana Ramos , Paiva Laís Mariano de , Silva Luciana Silverio Alleluia Higino da 
Published: November 2023

Aim: The purpose of this study is to identify, through an integrative review, the strategies implemented in partnership with the primary care team that contribute to promoting the mental health of adolescents at school.
Methods: 2,791 studies were identified, 389 in PubMed, 389 in Scopus, 320 in VHL, 04 in Scielo and 1,693 in GALE. After excluding duplicate studies and applying the eligibility criteria, 17 articles were selected.
Results: The analysis of the studies revealed that 18% of the articles addressed the relevance of the characteristics of promoting adolescent mental health in school in partnership with the primary care team, while another 18% were related to barriers faced in this promotion. Additionally, 41% of the articles dealt with the strategies used in this context and 24% discussed the associated challenges.
Discussion: Several strategies have been incorporated into the partnership between the education sector and Primary Health Care to promote the mental health of school adolescents.
Conclusions: Identifying the potential of actions and strategies carried out by education and primary health professionals reinforces the need for investments in spaces, materials and training of professionals aimed at promoting adolescent mental health.
Integrated Parylene‐Based Thin‐Film Microfluidic Device for Time‐Resolved Cryo‐Electron Microscopy
Authors: Hwang Haerang , Jung Bum‐Joon , Park Jiho , Jeong Yujin , Choi Yo‐han , Kang Jin Young , Lee Wonhee 
Published: January 2025

AbstractThe observation of transient protein complex structures facilitates a deeper understanding of the underlying biochemical reactions. However, conventional cryo‐electron microscopy (cryo‐EM) methods require tens of seconds for sample preparation, impeding the visualization of intermediate structures in short timescales. To address this limitation, time‐resolved cryo‐EM (TRCEM) is developed as a rapid sample preparation method that can mix and vitrify samples in a sub‐second timescale. However, polydimethylsiloxane (PDMS)‐based microfluidic devices, commonly employed in TRCEM methods, suffer from large sample consumption and high time heterogeneity, limiting their widespread implementation. Here, a parylene‐based microfluidic mixing‐spraying device is presented, which features a thin‐film structure containing a mixer and a spray nozzle in a single layer. The high bonding strength of the device enables it to withstand high channel pressure, facilitating rapid mixing at a wider range of flow rates. Furthermore, the spray nozzle, comprising an ultra‐thin parylene nozzle tip, generates a stable jet at low flow rates, thereby reducing sample consumption and time heterogeneity. The monolithic mixing‐spraying device design minimizes the internal volume, achieving an in‐chip reaction time of <1 ms. This setup will facilitate structural biology with reduced sample consumption and the capability of resolving faster dynamics of biochemical reactions.
Active Thermal Field Integration for Marangoni‐Driven Salt Rejection and Water Collection
Authors: Ge Can , Guo Shuai , Li Wei , Zhang Xunlong , Chen Bin , Feng Xiao , Yang Shichang , Xu Duo , Yu Zhen , Ravi Sai Kishore , Xu Weilin , Fang Jian , Tan Swee Ching 
Published: January 2025

AbstractUsing solar energy to drive seawater desalination via solar steam generation (SSG) is a sustainable strategy for clean water supply. The weak efficiency and poor durability due to salt deposition severely restrict practical SSG operation. Traditional solar evaporators are difficult to simultaneously guarantee efficient evaporation and long‐term salt rejection due to increased salinity. Herein, to tackle this dilemma, a thermal gradient fabric (TGF) evaporator with an auxiliary active thermal field is constructed. Different from traditional works where additional energy resources with improved evaporation rate exacerbate salt accumulation, the auxiliary active thermal field is well integrated with external solar energy to boost ion circulation through moderate Marangoni flow, leading to a continuous salt rejection and superior energy utilization under high‐salinity desalination. The accelerated evaporation rate (2.42 kg m−2 h−1) and superior salt resistance (30 days of desalination in 10 wt.% brine) are simultaneously achieved through optimized thermal field construction. An outstanding water collection rate (5.84 kg m−2) is observed during high‐salinity outdoor desalination, which proves the practical purification ability. This study provides new insight into the construction of active thermal fields for efficient and sustainable clean water production, is believed.
Nonlinear Harmonics: A Gateway to Enhanced Image Contrast and Material Discrimination
Authors: Biglarbeigi Pardis , Bhattacharya Gourav , Finlay Dewar , Payam Amir Farokh 
Published: January 2025

AbstractRecent advancements in atomic force microscopy (AFM) have enabled detailed exploration of materials at the molecular and atomic levels. These developments, however, pose a challenge: the data generated by microscopic and spectroscopic experiments are increasing rapidly in both size and complexity. Extracting meaningful physical insights from these datasets is challenging, particularly for multilayer heterogeneous nanoscale structures. In this paper, an unsupervised approach is presented to enhance AFM image contrast by analyzing the nonlinear response of a cantilever interacting with a material's surface using a wavelet‐based AFM. This method simultaneously measures different frequencies and harmonics in a single scan, without the need for additional hardware and exciting multiple cantilevers' eigenmodes. This developed AFM image contrast enhancement (AFM‐ICE) approach employs unsupervised learning, image processing, and image fusion techniques. The method is applied to interpret complex multilayer structures consist of defects, deposited nanoparticles and heterogeneities. Its substantial capability is demonstrated to improve image contrast and differentiate between various components. This methodology can pave the way for rapid and precise determination of material properties with enhanced resolution.
Nutritional benefits of pancreas‐sparing total duodenectomy for severe duodenal polyposis in patients with familial adenomatous polyposis
Authors: Fujinuma Ibuki , Ogura Toshiro , Takahashi Ayano , Nomura Satoshi , Kitamura Kei , Takahashi Amane , Shiraishi Takehiro , Mori Yoshiko , Ishiguro Toru , Matsuyama Takatoshi , Kumagai Youichi , Ishida Hideyuki 
Published: January 2025

AbstractAimSevere duodenal polyposis associated with familial adenomatous polyposis considerably increases the risk of duodenal cancer. Pancreas‐sparing total duodenectomy is an alternative surgical approach for managing severe duodenal polyposis. This study evaluated the postoperative nutritional outcomes following pancreas‐sparing total duodenectomy in patients with severe duodenal polyposis associated with familial adenomatous polyposis.MethodsThis retrospective analysis compared 28 patients who underwent pancreas‐sparing total duodenectomy for Spigelman stage IV duodenal polyposis with 29 patients who underwent pancreatoduodenectomy for low‐malignancy duodenal neoplasms. Patient demographics, postoperative complications, and nutritional parameters were analyzed at 3, 6, 9, and 12 months postoperatively.ResultsCompared with patients in the pancreatoduodenectomy group, those in the pancreas‐sparing total duodenectomy group were younger and had a higher incidence of previous abdominal surgeries (p < 0.01). Postoperatively, the pancreas‐sparing total duodenectomy group showed significantly better preservation of total protein, albumin, and total cholesterol levels, body mass index, body weight, and psoas major muscle area compared to the pancreatoduodenectomy group (p < 0.05). Additionally, glucose tolerance was better maintained in the pancreas‐sparing total duodenectomy group than in the pancreatoduodenectomy group (p < 0.01), with no patients requiring the initiation of insulin therapy or experiencing the exacerbation of diabetes.ConclusionsPancreas‐sparing total duodenectomy effectively preserves the postoperative nutritional status in patients with duodenal polyposis associated with familial adenomatous polyposis. This surgical option maintains postoperative nutritional integrity and improves long‐term outcomes.
Magnetic particle capture in high‐gradient magnetic separation: A theoretical and experimental study
Authors: Tesanovic Marko , de Souza J. Pedro , Bazant Martin Z. , Berensmeier Sonja 
Published: January 2025

AbstractHigh‐gradient magnetic separation (HGMS) has traditionally been used in mineral processing, with many effective models developed for typically employed rod‐wire shaped matrices. However, its potential in bioprocessing, especially for high‐value products, introduces new demands on plant and matrix design. This study presents a multi‐scale model for HGMS that simulates new complex geometries, which enhance particle recovery. We have developed microscopic models to accurately simulate the trajectories of magnetic particles within the fluid flow and magnetic fields of HGMS systems. A pivotal aspect of our work is the effective translation of microscopic relationships into macroscopic transport models. The model is validated experimentally using a rotor‐stator HGMS system tailored for bioprocessing, with magnetic particle concentration measurements showing strong alignment with the model's predictions. The model's flexibility enables its application across various matrix shapes, overcoming the limitations of traditional rod‐wire models, and providing a robust framework for improved HGMS in‐silico process understanding and optimization.
Phenotypic Expansion of Knobloch Syndrome Type 2 in an Individual With a De Novo PAK2 Variant
Authors: Werren Elizabeth A. , Kalsner Louisa , Ewald Jessica M. , Peracchio Michael , King Cameron , Vats Purva , Audano Peter A. , Robinson Peter N. , Adams Mark D. , Kelly Melissa A. , Matson Adam P. 
Published: January 2025

ABSTRACTP21‐activated kinase 2 (PAK2) is a serine/threonine kinase essential for a variety of cellular processes including signal transduction, cellular survival, proliferation, and migration. A recent report proposed monoallelic PAK2 variants cause Knobloch syndrome type 2 (KNO2)—a developmental disorder primarily characterized by ocular anomalies. Here, we identified a novel de novo heterozygous missense variant in PAK2, NM_002577.4:c.1273G>A, p.(D425N), by genome sequencing in an individual with features consistent with KNO2. Notable clinical phenotypes observed in this individual were global developmental delay, congenital retinal detachment, mild cerebral ventriculomegaly, hypotonia, failure to thrive, pyloric stenosis, feeding intolerance, patent ductus arteriosus, and mild facial dysmorphism. The p.(D425N) variant lies within the protein kinase domain and is predicted to be functionally damaging by in silico analysis. Previous clinical genetic testing did not report this variant due to unknown relevance of PAK2 variants at the time of testing, highlighting the importance of reanalysis. Our findings substantiate the candidacy of PAK2 variants in KNO2 and expand the KNO2 clinical phenotypic spectrum.
Sleep spindles and slow oscillations predict cognition and biomarkers of neurodegeneration in mild to moderate Alzheimer's disease
Authors: Páez Arsenio , Gillman Sam O. , Dogaheh Shahla Bakian , Carnes Anna , Dakterzada Faride , Barbé Ferran , Dang‐Vu Thien Thanh , Ripoll Gerard Piñol 
Published: January 2025

AbstractINTRODUCTIONChanges in sleep physiology can predate cognitive symptoms by decades in persons with Alzheimer's disease (AD), but it remains unclear which sleep characteristics predict cognitive and neurodegenerative changes after AD onset.METHODSUsing data from a prospective cohort of mild to moderate AD (n = 60), we analyzed non‐rapid eye movement sleep spindles and slow oscillations (SOs) at baseline and their associations with baseline amyloid beta (Aβ) and tau and with cognition from baseline to 3‐year follow‐up.RESULTSHigher spindle and SO activity predicted significant changes in Aβ and tau at baseline, lower Alzheimer's Disease Assessment Scale Cognitive Subscale (better cognitive performance) score, and higher Mini‐Mental State Examination score from baseline to 36 months. Spindles and SOs mediated the effect of phosphorylated tau 181 (pTau181)/Aβ42 on cognition, while pTau181/aβ42 moderated the effect of spindles and SOs on cognition.DISCUSSIONOur findings demonstrate that spindle and SO activity during sleep constitute predictive and non‐invasive biomarkers of neurodegeneration and cognition in AD patients.Highlights
Sleep spindles predict long‐term cognitive performance in AD.
Sleep spindle and SOs can be predictive, non‐invasive biomarkers for AD.
Sleep may be one of the most important modifiable risk factors for AD progression.
Sleep microarchitecture is a novel therapeutic target for preserving brain heath.
Sleep physiology can provide novel therapeutic targets to slow AD progression.
Niedertemperatur‐Atomlagenabscheidung von (00l)‐Orientiertem Elementarem Bismut
Authors: Vazquez‐Arce Jorge Luis , Amoroso Alessio , Perez Nicolas , Charvot Jaroslav , Naglav‐Hansen Dominik , Zhao Panpan , Yang Jun , Lehmann Sebastian , Wrzesińska‐Lashkova Angelika , Pieck Fabian , Tonner‐Zech Ralf , Bureš Filip , Acquesta Annalisa , Vaynzof Yana , Devi Anjana , Nielsch Kornelius , Bahrami Amin 
Published: January 2025

AbstractDiese Studie präsentiert den ersten erfolgreichen Nachweis der Herstellung von elementaren Bismut (Bi)‐Dünnfilmen mittels thermischer Atomlagenabscheidung (ALD) unter Verwendung von Bi(NMe2)3 als Präkursor und Sb(SiMe3)3 als Co‐Reaktant. Die Filme wurden bei einer relativ niedrigen Temperatur von 100 °C abgeschieden, mit einer Wachstumsrate pro Zyklus (GPC) von 0,31–0,34 Å/Zyklus. Die Anfangsstadien des Wachstums wurden durch Inselbildung geprägt, wobei die Oberflächenabdeckung nach etwa 1000 Zyklen 80 % erreichte und zwischen 2000 und 2500 Zyklen eine vollständige Abdeckung erzielt wurde. Morphologische Analysen zeigten, dass sich die Bi‐Körner mit zunehmender Anzahl von ALD‐Zyklen ausdehnten und klarer definiert wurden. Diese Koaleszenz wird durch Röntgenbeugungsmuster (XRD) weiter untermauert, die mit zunehmender Filmdicke eine präferenzielle Verschiebung der Wachstumsorientierung von der (012)‐Ebene zur (003)‐Ebene zeigen. Die Röntgen‐Photoelektronenspektroskopie (XPS) bestätigte das Vorhandensein von metallischem Bi mit minimaler Oberflächenoxidation. Temperaturabhängige Messungen des Flächenwiderstands unterstreichen die halbmetallischen Eigenschaften von Bi mit einem Raumtemperaturwiderstand von ≈200 μΩcm für die Filme mit 2500 Zyklen. Der temperaturabhängige Flächenwiderstand wurde auch mit einem Übergang in der Dominanz des Ladungsträgertyps von Löchern bei höheren Temperaturen zu Elektronen bei niedrigeren Temperaturen in Verbindung gebracht.
Imine‐Based Polymeric Mixed Ionic–Electronic Conductors Featuring Degradability and Biocompatibility for Transient Bioinspired Electronics
Authors: Chen Junxin , Cong Shengyu , Liu Riping , Duan Jiayao , Chen Chaoyue , Yu Dongsheng , Zhu Xiuyuan , Ran Chong , Cheng Du , Li Zhengke , McCulloch Iain , Yue Wan 
Published: January 2025

AbstractDegradable features are highly desirable to advance next‐generation organic mixed ionic–electronic conductors (OMIECs) for transient bioinspired artificial intelligence devices. It is highly challenging that OMIECs exhibit excellent mixed ionic‐electronic behavior and show degradability simultaneously. Specially, in OMIECs, doping is often a tradeoff between structural disorder and charge carrier mobilities. Here, we describe a regiochemistry‐driven backbone curvature approach to prepare OMIECs, enabling doped state ordered within efficient ionic‐electronic conduction in organic electrochemical transistors (OECTs) and presenting degradable characteristics. Significantly, i‐3gTIT shows an outstanding mobility (1.99 cm2 V−1 s−1) and μC* (302 F V−1 cm−1 s−1), and presents higher disorder‐tolerance upon doping and faster degradation behavior than its regioisomer, o‐3gTIT. Especially, the resulting OECT‐based inverter shows a high voltage gain of 31.6 V V−1 at a low driving voltage of 0.6 V. Moreover, we demonstrate an application of transient OECT, i. e., biodegradable solid‐state electrolyte of OECT‐based artificial synapses. Remarkably, the regiochemistry‐driven film crystallinity modulation enables the conversion from volatile to non‐volatile operation in such synapses. The transient synapse based on i‐3gTIT achieves over 90 % recognition accuracy for small digit handwritten images, showing potential in security neuromorphic computing. Our work is the first presentation enabling excellent mixed conduction of OMIECs with degradable features for transient bioinspired electronics.
Cationic Polyhedral Chalcogenaboranes: Activation without breaking Wade's Rules
Authors: Holub Josef , Náhlík Šimon‐Petr , Růžičková Zdeňka , Samsonov Maksim A. , Hnyk Drahomír , Cvačka Josef , Fanfrlík Jindřich , Vrána Jan , Růžička Aleš 
Published: January 2025

AbstractWade's rules are a well‐established tool for the description of the geometry of inorganic clusters. Among others, they state that a decrease or increase in charge is always accompanied by a change in the number of skeletal electron pairs (SEPs). This work reports the synthesis of the first cationic chalcogenaboranes closo‐[12‐X‐2‐IPr‐1‐EB11H10]BF4 (IPr=1,3‐(2,6‐iPr2C6H3)‐imidazole‐2‐ylidene; X=H, I; E=S, Se 3 a/b, 4 a/b) featuring the same SEP count as their neutral precursors, EB11H11, but bearing a positive charge. This ionisation significantly enhances the activity towards the electrophiles. It unlocks reactivity with very weak bases and offers the control of the regioselectivity towards hard/soft bases by the modulation of LUMO. The localisation of the positive charge within the borane cluster has been confirmed experimentally, spectroscopically and theoretically.
Low Temperature Atomic Layer Deposition of (00l)‐Oriented Elemental Bismuth
Authors: Vazquez‐Arce Jorge Luis , Amoroso Alessio , Perez Nicolas , Charvot Jaroslav , Naglav‐Hansen Dominik , Zhao Panpan , Yang Jun , Lehmann Sebastian , Wrzesińska‐Lashkova Angelika , Pieck Fabian , Tonner‐Zech Ralf , Bureš Filip , Acquesta Annalisa , Vaynzof Yana , Devi Anjana , Nielsch Kornelius , Bahrami Amin 
Published: January 2025

AbstractThis study presents the first successful demonstration of growing elemental bismuth (Bi) thin films via thermal atomic layer deposition (ALD) using Bi(NMe2)3 as the precursor and Sb(SiMe3)3 as the co‐reactant. The films were deposited at a relatively low temperature of 100 °C, with a growth per cycle (GPC) of 0.31–0.34 Å/cycle. Island formation marked the initial growth stages, with surface coverage reaching around 80 % after 1000 cycles and full coverage between 2000 and 2500 cycles. Morphological analysis revealed that the Bi grains expanded and became more defined as the number of ALD cycles increased. This coalescence is further supported by X‐ray diffraction (XRD) patterns, which show a preferential shift in growth orientation from the (012) plane to the (003) plane as the film thickness increases. X‐ray photoemission spectroscopy (XPS) confirmed the presence of metallic Bi with minimal surface oxidation. Temperature‐dependent sheet resistance measurements highlight the semimetallic nature of Bi, with a room temperature resistivity of ≈200 μΩcm for the 2500 cycles Bi. Temperature‐dependent sheet resistance was also associated with a transition in carrier‐type dominance from holes at higher temperatures to electrones at lower temperatures.
Regulating Interphase Chemistry by Targeted Functionalization of Hard Carbon Anode in Ester‐Based Electrolytes for High‐Performance Sodium‐Ion Batteries
Authors: Zhang Guangxiang , Fu Chuankai , Gao Shuyang , Zhao Haoquan , Ma Chi , Liu Ziwei , Li Shuai , Ju Zhijin , Huo Hua , Zuo Pengjian , Yin Geping , Liu Tiefeng , Ma Yulin 
Published: January 2025

AbstractCommercial hard carbon (HC) anode suffers from unexpected interphase chemistry rooted in the parasitic reactions between surface oxygen‐functional groups and ester‐based electrolytes. Herein, an innovative strategy is proposed to regulate interphase chemistry by tailoring targeted functional groups on the HC surface, where highly active undesirable oxygen‐functional groups are skillfully converted into a Si−O−Si molecular layer favorable for anchoring anions. Then, an inorganic/organic hybrid solid electrolyte interphase with low interfacial charge transfer resistance and enhanced cycling durability is constructed successfully. Consequently, the modified HC anode delivers an excellent rate capability of 206.2 mAh g−1 at 0.5 A g−1 and a remarkable capacity retention of 92.5 % after 1000 cycles at 1.0 A g−1. Moreover, the coin‐type full‐cell equipped with Na2Fe[Fe(CN)6] cathode exhibits an exceptional capacity retention ratio of 80.9 % after 800 cycles at 1C. The present simple and effective interfacial modification strategy offers a promising and alternative avenue for promoting the development and practicability of HC anode in ester‐based electrolytes for sodium‐ion batteries.
Exploring family dynamics in living funerals: Rituals to relationships
Authors: Tang Yuen‐Ki 
Published: January 2025

AbstractThis study aims to analyse how internal family relationships and dynamics are manifested during funeral ceremonies in Chinese society. As an emerging farewell practice, living funerals in Chinese societies depart from traditional death rituals, challenging established funeral paradigms and providing a platform to scrutinise the inner family dynamic and experiences. The study utilises a multidimensional data collection approach, including interviews with the living funeral holders and attending family members, detailed field notes during the living funeral and whole video recordings of the event. Employing narrative analysis, it delves into the family's life experiences as narrated during the funeral, providing insight into the emotional and relational shifts that occur. The findings suggest that while living funerals allow for exploring family roles and emotional landscapes, they also highlight the complex interplay of cultural practices and familial relationships. The study contributes to understanding how traditional taboos around death may be navigated through contemporary practices. Findings underscore the profound exploration of living funerals on family dynamics within Chinese culture. The practice provides a vital lens for examining the interconnectedness and emotional underpinnings of family relationships. Participation engages families in a process of navigating collective and individual histories, aiding reconciliation and affirming familial identities. Research highlights how living funerals powerfully express love, regrets and unspoken words, fostering deeper understanding and continuing bonds before death. Living funerals represent a meaningful contemporary practice, challenging traditional death taboos and offering therapeutic benefits for family therapy and end‐of‐life care. The paper contributes to the literature by addressing a crucial gap regarding living funerals within Chinese culture and expanding family perspectives on death. By examining how these ceremonies influence familial interactions, the study offers new insights into emotional and cultural dynamics, enhancing understanding of the practice and broader death‐related family issues.