bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of screening colonoscopy frequency on colorectal cancer mortality in patients with a family history of colorectal cancer
Authors: Zheng Li , Li Bin , Lei Ling , Wang Li-Jia , Zeng Zhi-Ping , Yang Jian-Dong 
Published: February 2024

BACKGROUND
Colorectal cancer is a common malignant tumor in China, and its incidence in the elderly is increasing annually. Inflammatory bowel disease is a group of chronic non-specific intestinal inflammatory diseases, including ulcerative colitis and Crohn’s disease.
AIM
To assess the effect of screening colonoscopy frequency on colorectal cancer mortality.
METHODS
We included the clinicopathological and follow-up data of patients with colorectal cancer who underwent laparoscopic colectomy or open colectomy at our Gastrointestinal Department between January 2019 and December 2022. Surgical indicators, oncological indicators, and survival rates were compared between the groups. The results of 104 patients who met the above criteria were extracted from the database (laparoscopic colectomy group = 63, open colectomy group = 41), and there were no statistically significant differences in the baseline data or follow-up time between the two groups.
RESULTS
Intraoperative blood loss, time to first ambulation, and time to first fluid intake were significantly lower in the laparoscopic colectomy group than in the open colectomy group. The differences in overall mortality, tumor-related mortality, and recurrence rates between the two groups were not statistically significant, and survival analysis showed that the differences in the cumulative overall survival, tumor-related survival, and cumulative recurrence-free rates between the two groups were not statistically significant.
CONCLUSION
In elderly patients with colorectal cancer, laparoscopic colectomy has better short-term outcomes than open colectomy, and laparoscopic colectomy has superior long-term survival outcomes compared with open colectomy.
Comprehensive analysis of the protein phosphatase 2A regulatory subunit B56ε in pan-cancer and its role and mechanism in hepatocellular carcinoma
Authors: Wu Hong-Mei , Huang Yuan-Yuan , Xu Yu-Qiu , Xiang Wei-Lai , Yang Chang , Liu Ru-Yuan , Li Di , Guo Xue-Feng , Zhang Zheng-Bao , Bei Chun-Hua , Tan Sheng-Kui , Zhu Xiao-Nian 
Published: February 2024

BACKGROUND
B56ε is a regulatory subunit of the serine/threonine protein phosphatase 2A, which is abnormally expressed in tumors and regulates various tumor cell functions. At present, the application of B56ε in pan-cancer lacks a comprehensive analysis, and its role and mechanism in hepatocellular carcinoma (HCC) are still unclear.
AIM
To analyze B56ε in pan-cancer, and explore its role and mechanism in HCC.
METHODS
The Cancer Genome Atlas, Genotype-Tissue Expression, Gene Expression Profiling Interactive Analysis, and Tumor Immune Estimation Resource databases were used to analyze B56ε expression, prognostic mutations, somatic copy number alterations, and tumor immune characteristics in 33 tumors. The relationships between B56ε expression levels and drug sensitivity, immunotherapy, immune checkpoints, and human leukocyte antigen (HLA)-related genes were further analyzed. Gene Set Enrichment Analysis (GSEA) was performed to reveal the role of B56ε in HCC. The Cell Counting Kit-8, plate cloning, wound healing, and transwell assays were conducted to assess the effects of B56ε interference on the malignant behavior of HCC cells.
RESULTS
In most tumors, B56ε expression was upregulated, and high B56ε expression was a risk factor for adrenocortical cancer, HCC, pancreatic adenocarcinoma, and pheochromocytoma and paraganglioma (all P < 0.05). B56ε expression levels were correlated with a variety of immune cells, such as T helper 17 cells, B cells, and macrophages. There was a positive correlation between B56ε expression levels with immune checkpoint genes and HLA-related genes (all P < 0.05). The expression of B56ε was negatively correlated with the sensitivity of most chemotherapy drugs, but a small number showed a positive correlation (all P < 0.05). GSEA analysis showed that B56ε expression was related to the cancer pathway, p53 downstream pathway, and interleukin-mediated signaling in HCC. Knockdown of B56ε expression in HCC cells inhibited the proliferation, migration, and invasion capacity of tumor cells.
CONCLUSION
B56ε is associated with the microenvironment, immune evasion, and immune cell infiltration of multiple tumors. B56ε plays an important role in HCC progression, supporting it as a prognostic marker and potential therapeutic target for HCC.
Global research trends and prospects of cellular metabolism in colorectal cancer
Authors: Liu Yan-Chen , Gong Zhi-Cheng , Li Chao-Qun , Teng Peng , Chen Yan-Yan , Huang Zhao-Hui 
Published: February 2024

BACKGROUND
An increasing number of studies have focused on the role of cellular metabolism in the development of colorectal cancer (CRC). However, no work is currently available to synthesize the field through bibliometrics.
AIM
To analyze the development in the field of “glucose metabolism” (GM), “amino acid metabolism” (AM), “lipid metabolism” (LM), and “nucleotide metabolism” (NM) in CRC by visualization.
METHODS
Articles within the abovementioned areas of GM, AM, LM and NM in CRC, which were published from January 1, 1991, to December 31, 2022, are retrieved from the Web of Science Core Collection and analyzed by CiteSpace 6.2.R4 and VOSviewer 1.6.19.
RESULTS
The field of LM in CRC presented the largest number of annual publications and the fastest increase in the last decade compared with the other three fields. Meanwhile, China and the United States were two of the most prominent contributors in these four areas. In addition, Gang Wang, Wei Jia, Maria Notarnicola, and Cornelia Ulrich ranked first in publication numbers, while Jing-Yuan Fang, Senji Hirasawa, Wei Jia, and Charles Fuchs were the most cited authors on average in these four fields, respectively. “Gut microbiota” and “epithelial-mesenchymal transition” emerged as the newest burst words in GM, “gut microbiota” was the latest outburst word in AM, “metastasis”, “tumor microenvironment”, “fatty acid metabolism”, and “metabolic reprogramming” were the up-to-date outbreaking words in LM, while “epithelial-mesenchymal transition” and “apoptosis” were the most recently occurring words in NM.
CONCLUSION
Research in “cellular metabolism in CRC” is all the rage at the moment, and researchers are particularly interested in exploring the mechanism to explain the metabolic alterations in CRC. Targeting metabolic vulnerability appears to be a promising direction in CRC therapy.
Poročila
Authors: Špes Metka , Komac Blaž , Cigale Dejan , Bobovnik Nejc , Rebernik Lea , Sitar Jasna , Ogrin Darko , Gregorčič Tim , Grad Jaka , Kropivšek Lena , Stefanovski Sašo , Stopar Job , Štaut Lenart , Repe Blaž , Tomić Dominik 
Published: February 2024

Uvod v študij geografije
Dolina Baruna pod Makalujem: znanstvene raziskave v okviru alpinističnih himalajskih odprav leta 1972 in 2014
Ekosistemska družbena ureditev
Akademija ob 90-letnici zaslužnega profesorja dr. Jurija Kunaverja in 20. Ilešičevi dnevi
Gamsova zbirka diapozitivov – ob 100-letnici rojstva geografa in krasoslovca akademika prof. dr. Ivana Gamsa (1923–2014)
Zaključek drugega ažuriranja funkcionalno razvrednotenih območij v Sloveniji
In the name of Soil – poročilo fizičnega dela mobilnosti Erasmus+
Kraško poletje v Ljubljani – historičnogeografska poletna šola
O hospital como lugar de pertencimento, possibilidades e ampliação do repertório ocupacional
Authors: Gurjão da Silva Viviany Letícia , Alves Malcher Allya Ariadne , Vieira Gomes Nathalia Sarmento 
Published: February 2024

Contextualização: Trata-se de uma análise prática sobre as possibilidades de ampliação do repertório ocupacional no hospital. Processo de Intervenção: Utilizou-se entrevista semiestruturada baseada na ciência da ocupação. Durante as intervenções, constatou-se que os pacientes se encontravam com suas ocupações modificadas em decorrência do adoecimento e da hospitalização. Análise crítica da prática: O terapeuta ocupacional, no ambiente hospitalar, por meio de uso de diferentes atividades, explora e resgata habilidades e capacidades do sujeito, com vistas a possibilitar vivências saudáveis. Síntese das considerações: O hospital pode permitir o resgate de ocupações e ampliação do repertório ocupacional.
Palavras-chaves: Hospitalização. Serviço Hospitalar de Terapia Ocupacional. Terapia Ocupacional.
Abstract
Contextualization: This is a practical analysis of the possibilities of expanding the occupational repertoire in the hospital. Intervention Process: A semi-structured interview based on the science of occupation was used. During the interventions, it was found that the patients found their occupations changed as a result of illness and hospitalization. Critical analysis of the practice: The occupational therapist in the hospital environment, through the use of different activities, explores and rescues the subject's skills and abilities, with a view to enabling healthy experiences. Summary of considerations: The hospital can allow the rescue of occupations and expansion of the occupational repertoire.
Key words: Hospitalization. Occupational Therapy Department, Hospital. Occupational Therapy.
Resumen
Contextualización: Se trata de un análisis práctico de las posibilidades de ampliación del repertorio ocupacional en el hospital. Proceso de Intervención: Se utilizó una entrevista semiestructurada basada en la ciencia de la ocupación. Durante las intervenciones, se constató que los pacientes cambiaron sus ocupaciones como consecuencia de la enfermedad y la hospitalización. Análisis crítico de la práctica: El terapeuta ocupacional en el ambiente hospitalario, a través del uso de diferentes actividades, explora y rescata las habilidades y destrezas del sujeto, con miras a posibilitar experiencias saludables. Resumen de consideraciones: El hospital puede permitir el rescate de ocupaciones y ampliación del repertorio ocupacional.
Palabras clave: Hospitalización. Servicio de Terapia Ocupacional en Hospital. Terapia Ocupacional.
Phenotyping and Genotyping of Saprolegnia parasitica isolated from Diwaniyah River-Iraq
Authors: Al-Ameri Kadhim H.A 
Published: February 2024

The current study included a study of the spread of Saprolegnia parasitica in the water of the Diwaniyah River, water samples were collected for three months from the Al-Furat Bridge area for three months August, September, and October, isolation was done by bait method. After that, diagnosis was made by the traditional method adopted to explain the appearance and was supported by molecular diagnosis by PCR. The results showed that the fungus S.parasitica was present in varying numbers and percentages according to the months of the study, the numbers increased with decreasing temperatures, as they were month of October was the highest month in terms of the number of isolates, as it reached 10, representing a percentage of 46%, while the month of September had 8 isolates, a percentage of 36%, and the month of August. It was the lowest, as it was 4, with a rate of 18%. The molecular study appeared that the diagnosis of all isolates was identical to the traditional diagnosis, which relies on the appearance of the fungus in plates and under an optical microscope, where the bands were at 568 bp.
Mehr Gender Balance schaffen
Authors: Tietze Iris 
Published: February 2024

Der Konsumgüterhersteller Reckitt hat das Ziel, ein ausgewogenes Geschlechterverhältnis auf allen Führungsebenen zu erreichen. Günter Bernhard, der neue HR-Direktor für Deutschland, Österreich, die Schweiz und die skandinavischen Länder, spricht mit der LZ über seine Strategie, über Effizienzinitiativen im HR-Bereich und die positiven Impulse, die die Gen Z ins Business bringt.
PENGARUH PROFITABILITAS, NILAI PASAR, LIKUIDITAS DAN LEVERAGE TERHADAP HARGA SAHAM
Authors: Setiawan Sandrika Widya Putri , Kalsum Ummi , Kosim Belliwati 
Published: February 2024

ABSTRACT
This study aims to determine the effect of profitability, market value, liquidity, and leverage on stock prices in companies in the consumer goods industry sector which are listed on the IDX simultaneously and partially. The samples used in this study were 6 companies in the cosmetics and household goods sub-sector on the IDX for the 2017-2021 period using a purposive sampling method. This type of research uses quantitative research. The results of the study simultaneously show that profitability, market value, liquidity and leverage have a significant effect on stock prices. Partially, it shows that profitability (ROA) has a significant effect on stock prices, market value (EPS) has a significant effect on stock prices, liquidity (CR) has a significant effect on stock prices, and leverage (DAR) has no significant effect on stock prices.
Keywords : Profitability, Market Value, Liquidity, Leverage, Stock Price
PENGARUH TRANSFORMATIONAL LEADERSHIP TERHADAP READINESS FOR CHANGE: DIMEDIASI OLEH ORGANIZATIONAL TRUST
Authors: Husna Radiatul , Zaitul Zaitul , Nofriadi Rizki , Stevany Stevany , Stevany Stevany , Khalil Idham , Razaq Al-Lya , Yurizal Yurizal , Putra Sandi Cokes , Buana Genta 
Published: February 2024

ABSTRAK
The purpose of this study was to determine the effect of transformational leadership on readiness for change which was intervened by organizational trust among the employee in the Class II Navigation District Office of Type A Teluk Bayur, Padang, Indonesia. The method used is quantitative techniques by distributing surveys to employees of the Navigation District Office Type A Class II Teluk Bayur. The final sample of research is 52 respondents. The primary data is applied using questioner. The variable is measured by five Likert scales starting from very much disagree (1) to very much agree (5). Data is analysed using the structural equation model (SEM)PLS. in this case, we use the smart pls 3. The finding show that organizational trust mediates the relationship between transformational leadership and readiness for change. In addition, this study also documented two significant direct relationships: (i) the relationship between transformational leadership and organizational trust, and (ii) the relationship between organizational trust and readiness for change. This study has a theoretical and practical implications, and they are discussed detail in paper.
Keywords: transformational leadership, organisational trust, readiness for change
PENGARUH LINGKUNGAN KERJA, DISIPLIN DAN MOTIVASI TERHADAP KINERJA DAN PRODUKTIVITAS KERJA
Authors: Mindari Ellisyah , Marsih Yeni 
Published: February 2024

Abstract
The development of excellent human resources that are well directed, well coordinated, and supported by other elements like the work environment, discipline, and motivation in reaching organizational goals optimally through the management of work performance and productivity by employees can lead to organizational success. This research involved a simultaneous or partial investigation of the effects of the work environment (x1), discipline (x2), and motivation (x3) on performance (y1) and work productivity (y2). Survey research is the methodology (quantitative). The problem formulation is associative in the sense of a causal relationship, depending on the level of explanation. 61 samples from a population of 157 with a 10% confidence level with the Slovin formula. With the aid of IBM SPSS Statistics 26, the data were examined for validity, reliability, multiple regression analysis, coefficient of determination, simultaneous and individual tests. We found the multiple regression equations y1=-8,466+0,539x1+0,302x2+0,124x3 and y2=-7,514+0,493x1+0,326x2+0,137x3.. The R Square value was found to indicate that whereas other models affect 22,6% of employee performance, independent factors simultaneously influence 77,4% of it. The independent variable is read as accounting for 75,3% of work productivity, with other factors accounting for the remaining 24,7%, based on the determinant coefficient value of 0,753. The statistical regression test findings show that the independent variables have a positive and substantial combined influence on the dependent variable, with x1 having the greatest and most dominant effect, the consequent variable are significantly and positively impacted by motivation and discipline.
Keywords: Work Environment, Discipline, Motivation, Performance, Work Productivity
PENGARUH DISIPLIN KERJA DAN KEMAMPUAN KERJA TERHADAP KINERJA PEGAWAI BADAN KEPEGAWAIAN DAN PENGEMBANGAN SDM (BKPSDM) KABUPATEN MUSI BANYUASIN
Authors: Erlina Neti , Calista Avissa 
Published: February 2024

Abstract

The Personnel and HR Development Agency (BKPSDM) of Musi Banyuasin Regency was formed through Regional Regulation Number 22 of 2010 as a Government Implementing Element that is directly familiar with all matters of the Musi Banyuasin Regency Government in the Field of Personnel and Training as per the Regional Regulation. The data processing technique for this research used the SPSS version 19 computer. The research method used was a quantitative descriptive method. Data collection techniques used are questionnaires, observation and documentation. Data analysis was performed using validity test, reliability test, classical assumption test, multiple linear regression, correlation coefficient and hypothesis testing (t test and F test). The results of this study indicate that work discipline and work ability have an effect on performance. the variables of work discipline and work ability affect performance by 64.3 percent, while the remaining 35.7 percent are influenced by variables not examined in this study.
Keywords: Discipline, Ability, Performance
PENGARUH LINGKUNGAN KERJA TERHADAP KINERJA KARYAWAN PADA LEMBAGA AMIL ZAKAT NASIONAL YATIM MANDIRI PALEMBANG
Authors: Haqiqi Teuku Muhammad , Hanifa Riri , Anggara Bayu 
Published: February 2024

ABSTRACT
This study aims to determine whether there is an influence between the work environment on employee performance at the Palembang Yatim Mandiri National Amil Zakat Institute. The sampling technique used is the saturated sampling technique. The research sample is 45 employees. The data analysis used was descriptive analysis, quantitative analysis, simple regression analysis, hypothesis testing (t), and the coefficient of determination using SPSS version 25. The results showed that the work environment (X) had a significant positive effect on employee performance (Y). In the test results of the coefficient of determination (R2) a value of 0.847 is obtained. This means that the influence of the work environment on employee performance is 84.7%, while the remaining 15.3% is influenced by other factors not examined in this study.
Keywords: Work Environment, Employee Performance
THE PRACTICE OF MASTERING THE TECHNOLOGY OF COKING RAMMED COAL BY THE CHEREPOVETS METALLURGICAL PLANT USING ITS OWN TECHNOLOGICAL AND TECHNICAL SOLUTIONS
Authors: Калько А.А. , Чикинов С.В. , Карунова Е.В. , Калько О.А. 
Published: February 2024

Череповецкий металлургический комбинат ПАО «Северсталь» ввел в эксплуатацию коксовую батарею № 11 (КБ № 11) с технологией производства высококачественного кокса из трамбованных слабоспекающихся углей. В статье рассмотрены конструктивные особенности коксовой батареи, изложены собственные технические и технологические способы решения проблем, возникших при внедрении уникальной для России технологии коксования трамбованных шихт.
Cherepovets Stell mill of PJSC «Severstal» put into operation coke oven battery № 11 (CB № 11) with a technology for the production of high-quality coke from compacted low-caking charges. The article discusses the design features of the coke oven battery, sets out its own technical and technological solutions to the problems that arose during the implementation of the unique technology for coking rammed charges in Russia.
EFFECT OF HIGH-TEMPERATURE EXPOSURE ON THE FRACTURE TOUGHNESS OF THE WELD METAL OF LOW-CARBON STEEL WELDED JOINT
Authors: Никулин С.А. , Рогачев С.О. , Белов В.А. , Шплис Н.В. , Турилина В.Ю. , Федоренко Л.В. , Моляров А.В. , Ожерелков Д.Ю. 
Published: February 2024

Проведено сравнительное испытание на вязкость разрушения (трещиностойкость) образцов металла шва сварного соединения из низкоуглеродистой стали в состоянии поставки и после высокотемпературного воздействия при температуре 1200 °С в течение 3,7 ч. Сварное соединение получали методом автоматической аргонодуговой сварки плавящимся электродом на горячекатаном листе толщиной 60 мм из стали 22К, используя сварочную проволоку марки СВ-08Г2С. Испытания на статическую трещиностойкость образцов с концентратором напряжений проводили по схеме трехточечного изгиба. В качестве характеристики трещиностойкости использовали один из энергетических критериев нелинейной механики разрушения – критический J-интеграл [Дж/м2], учитывающий пластическую деформацию в вершине трещины. Показано, что высокотемпературное воздействие приводит к повышению трещиностойкости (значение J-интеграла увеличивается в два раза) в результате фазовой перекристаллизации и исправления крупнозернистой перегретой структуры сварного шва.
A comparative test for crack resistance (fracture toughness) of the samples of the weld metal of a low-carbon steel welded joint in the asdelivered condition and after high-temperature exposure at a temperature of 1200 °C for 3.7 hours was carried out. The welded joint was obtained by automatic argon-arc welding with a consumable electrode on a hot-rolled 22K-type steel sheet of 60 mm thick using welding wire grade SV-08G2S. The tests for static crack resistance of the samples with a stress concentrator were carried out according to the three-point bending scheme. One of the energy criteria of nonlinear fracture mechanics, the critical J-integral [J/m2], which takes into account plastic deformation at the crack tip, was used as a crack resistance characteristic. It is shown that the high-temperature exposure leads to an increase in crack resistance (the J-integral value increases by 2 times) as a result of phase recrystallization and improving the coarse-grained overheated structure of the weld.
Adoption of Mobile Phone Based Mutual Fund Investment Applications Among Retail Investors: Empirical Evidence from UTAUT Model
Authors: Dr. Ajay Pratap Yadav Ratnesh Kumar Yadav, 
Published: February 2024

Objective- This study aims to analyse acceptance of mobile phone based mutual fund applications. The objective, in other way examines how mutual fund mobile apps affect retail investors' investment decisions.
Methodology- Under the Unified Theory of Acceptance and Use of Technology (UTAUT), the paper observed retail investor’s adoption behaviour prediction. The data was collected during April–September, 2023 using structured questionnaire. Based on total 258 viable replies, the study used multiple regression and regression coefficient analysis.
Results– The study found that effort expectancy (EE), performance expectancy (PE), social influence (SI), facilitating condition (FC), and habit (H) influenced retail investors' mutual fund mobile app use. Hedonic motivation did not affect retail investors' mutual fund mobile application behavioural intention.