bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid nursing redeployment from a specialist ward to a COVID-19 high-dependency setting
Authors: Robinson Rachel , Madge Susan 
Published: February 2024

Background: Redeployment in health care can have a negative impact on the mental wellbeing of staff. Advanced planning and provisions for wellbeing support for health professionals has been recommended following previous pandemics. At the authors' institution nurses were redeployed overnight from a specialist cystic fibrosis ward to a COVID-19 high-dependency unit. Aim: To evaluate nurses' wellbeing following this redeployment during the first wave of the COVID-19 pandemic. Method: A mixed online survey, consisting of both open and closed questions, based on literature, preliminary results of the Impact of COVID-19 on the Nursing and Midwifery Workforce (ICON) study and staff feedback. This was sent to 28 nurses to explore their feelings and experiences of redeployment to a COVID-19 environment. Purposive sampling was used to select study participants while thematic analysis and descriptive statistics were used to analyse the data. Findings: The survey had an 86% response rate. Using thematic analysis three key themes emerged: redeployment anxiety, lack of organisational preparedness and newfound teamworking. More than half (57%) of respondents expressed anxiety and concern when told of their redeployment; 52% reported that they did not receive adequate support from senior staff and management. However, 74% reported that they felt their nursing was positively influenced by support and teamwork from those in patient-facing roles. Twenty-five percent reported that they were looking for a new job or leaving their current role. Conclusion: This study examines the effects that redeployment to a COVID-19 environment has had on nurses. It highlights the need for further improvement to ensure redeployed staff are supported to safeguard their mental wellbeing.
Experimental optimization design synthesis for up-conversion luminescence performance in SrBi4Ti4O15: Er3+/Yb3+ red-green phosphors
Authors: Liu Shengyi , Gao Duan , Wang Li , Song Wenbin , Zhang Zhiliang , Wang Shitao , Zhu Ying , Zhang Qi 
Published: February 2024

Er3+/Yb3+ co-doped SrBi4Ti4O15 crystalline powders were synthesized using the high-temperature solid-phase method. The crystal structure of the obtained phosphors was analyzed through x-ray diffraction (XRD), confirming the purity of all products such as SrBi4Ti4O15. Employing experimental design optimization theory, regression equations were established to correlate the Er3+/Yb3+ doping concentrations with the luminescent intensities. The genetic algorithm was utilized to compute the optimal solutions of the equations, resulting in Er3+ and Yb3+ doping concentrations of 3 mol% (molar fraction) and 20 mol% under 980 nm laser excitation and 3 mol% and 29.79 mol% under 1550 nm laser excitation. The up-conversion fluorescence emission spectra of the samples were measured under 980 nm excitation, revealing intense green emissions at 525 nm, 550 nm, and 662 nm, corresponding to the 2H11/2→4I15/2, 4S3/2→4I15/2, and 4F9/2→4I15/2 energy levels, respectively. Under 1550 nm excitation, peaks corresponding to the same energy levels were observed at 523 nm, 548 nm, and 661 nm. The relationship between the up-conversion fluorescence and the laser operating current for the optimal samples under 980 nm and 1550 nm excitations was explored, indicating two-photon and three-photon processes, respectively. Detailed analysis and discussion of the up-conversion fluorescence mechanisms were conducted. Additionally, the relationship between the up-conversion fluorescence and the temperature for the optimal samples was investigated, revealing excellent temperature sensing characteristics under 980 and 1550 nm laser excitations. The CIE coordinates for the optimal samples were calculated as (0.3111, 0.6747) and (0.5254, 0.4671) under 980 nm and 1550 nm excitations, respectively.
Tumor necrosis factor inhibitors and janus kinase inhibitors in the treatment of cicatricial alopecia: A systematic review
Authors: Hajizadeh Nima , Heidari Amirhossein , Sadeghi Sara , Goodarzi Azadeh 
Published: February 2024

BackgroundCicatricial alopecia (CA) refers to various conditions that result in permanent hair loss. Treatment of CA has always been challenging. Regarding immune-mediated pathophysiology for many CA subtypes, the administration of Janus kinase (JAK) and tumor necrosis factor (TNF) inhibitors have potentiated the treatments of CA.MethodsAfter a thorough systematic search in PubMed/Medline, Embase, Web of Science, Scopus, Google Scholar, ClinicalTrials.gov, and WHO ICTRP, a total of 3,532 relevant records were retrieved and screened. Accordingly, 56 studies met the eligibility criteria and entered the review.ResultsAmong JAK inhibitors, oral tofacitinib was the most frequently reported and the most effective treatment in improving signs and symptoms of CA with minimal adverse effects (AEs). Baricitinib was another JAK inhibitor with sustained improvement while causing mild AEs. As a TNF inhibitor, adalimumab induced a rapid and stable improvement in signs and symptoms in most patients with rare, tolerable AEs. Thalidomide was the other frequently reported yet controversial TNF inhibitor, which caused a rapid and significant improvement in the condition. However, it may result in mild to severe AEs, particularly neuropathies. Infliximab is a TNF inhibitor with mostly favorable results, albeit in a few patients caused treatable dermatological AEs. Apremilast and certolizumab pegol caused an incomplete amelioration of signs and symptoms with no AEs. Lenalidomide is another TNF inhibitor that can induce temporary improvement in CA with probable AEs. It is noteworthy that utilizing adalimumab, infliximab, etanercept, golimumab, and an anonymous TNF inhibitor has induced paradoxical CA and other A.E.s in some patients.ConclusionRecent studies have recommended JAK and TNF inhibitors, especially oral tofacitinib and adalimumab, as a new modality or adjuvant therapy to previous medications for primary CA. Nonetheless, monitoring AEs on a regular basis is suggested, and further extensive studies are required before definitive recommendations.
COVID-19 in patients presenting with malaria-like symptoms at a primary healthcare facility in Accra, Ghana
Authors: Asamoah Issabella , Adusei-Poku Mildred , Vandyck-Sey Priscilla , Steele-Dadzie Allen , Kuffour Atta Senior , Turkson Albert , Asante Ivy Asantewaa , Addo-Osafo Kantanka , Mohktar Quaneeta , Adu Bright , Afrane Yaw A. , Sagoe Kwamena W. C. 
Published: February 2024

Background
Malaria is a common and severe public health problem in Ghana and largely responsible for febrile symptoms presented at health facilities in the country. Other infectious diseases, including COVID-19, may mimic malaria due to their shared non-specific symptoms such as fever and headache thus leading to misdiagnosis. This study therefore investigated COVID-19 among patients presenting with malaria-like symptoms at Korle-Bu Polyclinic, Accra, Ghana.

Methods
This study enrolled 300 patients presenting with malaria-like symptoms aged ≥18yrs. After consent was obtained from study patients, two to three millilitres of whole blood, nasopharyngeal and oropharyngeal swab samples, were collected for screening of Plasmodium falciparum using malaria rapid diagnostic test, microscopy and nested PCR, and SARS-CoV-2 using SARS-CoV-2 antigen test and Real-time PCR, respectively. The plasma and whole blood were also used for COVID-19 antibody testing and full blood counts using hematological analyser. SARS-CoV-2 whole genome sequencing was performed using MinIon sequencing.

Results
The prevalence of malaria by microscopy, RDT and nested PCR were 2.3%, 2.3% and 2.7% respectively. The detection of SARS-CoV-2 by COVID-19 Rapid Antigen Test and Real-time PCR were 8.7% and 20% respectively. The Delta variant was reported in 23 of 25 SARS-CoV-2 positives with CT values below 30. Headache was the most common symptom presented by study participants (95%). Comorbidities reported were hypertension, asthma and diabetes. One hundred and thirteen (37.8%) of the study participants had prior exposure to SARS CoV-2 and (34/51) 66.7% of Astrazeneca vaccinated patients had no IgG antibody.

Conclusion
It may be difficult to use clinical characteristics to distinguish between patients with COVID-19 having malaria-like symptoms. Detection of IgM using RDTs may be useful in predicting CT values for SARS-CoV-2 real-time PCR and therefore transmission.
Generációs olvasmányok? Irodalmi pedofília?
Authors: Urbanik Tímea 
Published: February 2024

A Kapocs Kutatócsoport 2022-es szegedi olvasáskutatásának felső tagozatosai mind digitális bennszülöttek, a Z generáció utolsó éveiben születtek. Válaszaik összevetése a 11 évvel korábbi szegedi olvasáskutatás adataival (Bozsó et al. 2011), s a 2017-es és 2019-es országos reprezentatív olvasáskutatás adataival (Tóth 2020) generációs sajátosságok és trendszerű változások megfigyelését segíti.
Mit mutat a kedvenc olvasmányok listája, milyen kapcsolatban áll a kötelező olvasmányokkal, s az életkori sajátosságokkal? Milyen műfajok, szerzők, sorozatok, brandek irányába fogékony a felsős korosztály. Vannak-e jelenleg generációs olvasmányok? S mindennek vannak-e szegedi, lokális vonatkozásai? Ezekre a kérdésekre keresi a válaszokat a tanulmány a szegedi 2022-es kutatás 421 felső tagozatos adatközlőjének válaszait összevetve a 2011-es szegedi kutatás 343 adatközlőjével és a 2017-es és 2019-es országos reprezentatív kutatás adataival.
Increased Intestinal Permeability and Decreased Resiliency of the Intestinal Barrier in Alcoholic Liver Disease
Authors: Swanson Garth R. , Garg Kanika , Shaikh Maliha , Keshavarzian Ali 
Published: February 2024

Objectives:
Only 20- 30% of individuals with Alcohol Use Disorder (AUD) develop Alcoholic Liver Disease (ALD). While the development of gut-derived endotoxemia is understood to be a required co-factor, increased intestinal permeability in ALD is not completely understood.

Methods:
We recruited 178 subjects – 58 healthy controls (HC), 32 with ALD, 53 with AUD but no liver disease (ALC), and 35 with nonalcoholic fatty liver disease (NAFLD). Intestinal permeability was assessed by a sugar cocktail as a percentage of oral dose. The permeability test was repeated after an aspirin challenge in a subset.

Results:
5 hour urinary Lactulose/Mannitol (L/M) Ratio (primarily representing small intestinal permeability) was not statistically different in HC, ALC, ALD, and NAFLD (p=0.40). 24 hour urinary Sucralose (representing whole gut permeability) was increased in ALD (F= 5.3, p < 0.01) and distinguished ALD from ALC; 24 hour sucralose/lactulose (S/L) ratio (primarily representing colon permeability) separated the ALD group (F= 10.2, p<0.01) from NAFLD. After aspirin challenge, intestinal permeability increased in all groups and ALD had the largest increase.

Conclusions:
In a cohort of patients, we confirmed that (1) ALD has increased intestinal permeability compared to HC, ALC, or NAFLD. In addition, since small bowel permeability (L/M ratio) is normal, the disruption of intestinal barrier appears to be primarily in the large intestine.; (2) Decreased resiliency of intestinal barrier to injurious agents (like NSAID) might be the mechanism for gut leak in subset of AUD who develop ALD.
Vanishing and blow-up solutions to a class of nonlinear complex differential equations near the singular point
Authors: Diblík Josef , Růžičková Miroslava 
Published: February 2024

Abstract
A singular nonlinear differential equation

z

σ

d
w

d
z

=
a
w
+
z
w
f

(

z
,
w

)

,

{z}^{\sigma }\frac{{\rm{d}}w}{{\rm{d}}z}=aw+zwf\left(z,w),

where

σ
>
1

\sigma \gt 1

, is considered in a neighbourhood of the point

z
=
0

z=0

located either in the complex plane

C

{\mathbb{C}}

if

σ

\sigma

is a natural number, in a Riemann surface of a rational function if

σ

\sigma

is a rational number, or in the Riemann surface of logarithmic function if

σ

\sigma

is an irrational number. It is assumed that

w
=
w

(

z

)

w=w\left(z)

,

a
∈
C
⧹

{

0

}

a\in {\mathbb{C}}\setminus \left\{0\right\}

, and that the function

f

f

is analytic in a neighbourhood of the origin in

C
×
C

{\mathbb{C}}\times {\mathbb{C}}

. Considering

σ

\sigma

to be an integer, a rational, or an irrational number, for each of the above-mentioned cases, the existence is proved of analytic solutions

w
=
w

(

z

)

w=w\left(z)

in a domain that is part of a neighbourhood of the point

z
=
0

z=0

in

C

{\mathbb{C}}

or in the Riemann surface of either a rational or a logarithmic function. Within this domain, the property

lim

z
→
0

w

(

z

)

=
0

{\mathrm{lim}}_{z\to 0}w\left(z)=0

is proved and an asymptotic behaviour of

w

(

z

)

w\left(z)

is established. Several examples and figures illustrate the results derived. The blow-up phenomenon is discussed as well.
Learning about Confucian ecological ethics to promote education for sustainable development in Chinese secondary chemistry education
Authors: Li Baoyu , Eilks Ingo 
Published: February 2024

Abstract
Incorporating cultural aspects into science education has recently been stressed in many non-Western societies. However, Chinese traditional cultures are rarely discussed in Chinese science classrooms. Hence, a teaching intervention integrating Confucian ecological ethics and education for sustainable development in secondary chemistry classrooms was designed, implemented online due to the COVID-19 pandemic, and analyzed. It focuses on discussing aspects of Confucian ecological ethics in the context of a lesson plan on the socio-scientific issue of plastic use. Sixty-five 10th-grade students from an urban key public high school in Beijing voluntarily attended this research. Based on the analysis of their feedback it is suggested that Confucian ecological ethics can improve students’ environmental awareness. Most students acknowledged that Confucian ecological ethics could promote Chinese sustainability-oriented chemistry education with a value-oriented approach.
The acceptability of Songs of Love for youth living with chronic pain
Authors: Donovan Elizabeth , Green Vanya , Feldman Greg , Tachdjian Raffi , Curry Caitlin , Rice Charlotte , Zeltzer Lonnie K. 
Published: February 2024

Abstract

Objectives
Music is helpful to young people in healthcare contexts, but less is known about the acceptability of music-based interventions for youth living at home with chronic pain who may be struggling to attend school and participate in social activities. The Songs of Love (SOL) foundation is a national nonprofit organization that creates free, personalized, original songs for youth facing health challenges. The aims of this study were (1) to assess acceptability of SOL from the perspective of youth with chronic pain receiving a song and singer-songwriters who created the songs, and (2) to explore the role of music more generally in the lives of young people living with pain.

Methods
Twenty-three people participated. Fifteen youth (mean age 16.8) were interviewed and received a song, and six singer-songwriters were interviewed about creating the songs. (Two additional people participated in pilot interviews.) Acceptability was assessed by (1) proportion of youth who participated in a second interview about their song and (2) results of reflexive thematic analysis (RTA) to determine acceptability. Themes addressing the role of music in the lives of youth with pain were also explored using RTA.

Results
The program was acceptable as 12 of 15 youth (80 %) participated in second interviews and themes met the definition of acceptability. Three themes addressing the role of music in the lives of youth living with pain were identified.

Conclusions
This is the first report of the acceptability and experience of SOL and contributes to research on the benefits of music for pain management.
Predictive factors for lung metastasis in pediatric differentiated thyroid cancer: a clinical prediction study
Authors: Kuang Hou-fang , Lu Wen-liang 
Published: February 2024

Abstract

Objectives
The objective of this study was to develop and evaluate the efficacy of a nomogram for predicting lung metastasis in pediatric differentiated thyroid cancer.

Methods
The SEER database was utilized to collect a dataset consisting of 1,590 patients who were diagnosed between January 2000 and December 2019. This dataset was subsequently utilized for the purpose of constructing a predictive model. The model was constructed utilizing a multivariate logistic regression analysis, incorporating a combination of least absolute shrinkage feature selection and selection operator regression models. The differentiation and calibration of the model were assessed using the C-index, calibration plot, and ROC curve analysis, respectively. Internal validation was performed using a bootstrap validation technique.

Results
The results of the study revealed that the nomogram incorporated several predictive variables, namely age, T staging, and positive nodes. The C-index had an excellent calibration value of 0.911 (95 % confidence interval: 0.876–0.946), and a notable C-index value of 0.884 was achieved during interval validation. The area under the ROC curve was determined to be 0.890, indicating its practicality and usefulness in this context.

Conclusions
This study has successfully developed a novel nomogram for predicting lung metastasis in children and adolescent patients diagnosed with thyroid cancer. Clinical decision-making can be enhanced by assessing clinicopathological variables that have a significant predictive value for the probability of lung metastasis in this particular population.
Structural and morphological properties of CdSe1-xSx thin films obtained by the method of high-frequency magnetron sputtering
Authors: Kashuba A.I. , Semkiv I.V. , Andriyevsky B. , Ilchuk H.A. , Pokladok N.T. 
Published: February 2024

CdSe1-xSx (x= 0.3, 0.4 and 0.6) thin films were deposited on quartz and silicon substrates by the method of high-frequency magnetron sputtering. The chemical composition analysis and crystal structure refinement was examined with using X-ray fluorescence spectroscopy and X-ray diffraction data. CdSe1-xSx thin films crystallizes in hexagonal structure (structure type – ZnO, space group P63mc (No. 186)). The lattice parameters (a, c and V), crystallite size (D), strain (ε), dislocation density (δ) and the texture coefficient TC(hkl) was estimated from X-ray diffraction analysis. Units-cell parameters decrease with increasing S content in CdSe1-xSx thin film.
Strategies to overcome electron-beam issues in liquid phase TEM: Study of chemical processes
Authors: Zheng Wenjing , Lee Daewon , Zheng Haimei 
Published: February 2024

AbstractLiquid phase (or liquid cell) transmission electron microscopy (TEM) has become a powerful platform for in situ investigation of various chemical processes at the nanometer or atomic level. The electron beam for imaging can also induce perturbation to the chemical processes. Thus, it has been a concern that the observed phenomena in a liquid cell could deviate from the real-world processes. Strategies have been developed to overcome the electron-beam-induced issues. This article provides an overview of the electron-beam effects, and discusses various strategies in liquid cell TEM study of nucleation, growth, and self-assembly of nanoscale materials, where an electron beam is often used to initiate the reactions, and highly electron-beam-sensitive electrochemical reactions.
Graphical abstract
Determination of hydrolyzing and ethanolic potential of cellulolytic bacteria isolated from fruit waste
Authors: Shehzadi Areeba , Chaudhary Asma , Aihetasham Ayesha , Hussain Nageen , Naz Sumaira , Aziz Tariq , Alasmari Abdullah F. 
Published: February 2024

Fruit wastes containing cellulose can be made valuable by cellulolytic bacteria in biofuel production. This study aimed to assess the potential of isolated cellulolytic bacteria to produce bioethanol and its fermentation efficiency. Seven out of 16 bacterial isolates were selected on the basis of their cellulose-degrading potential by providing cellulose as the only carbon source. Their potential to degrade cellulose was determined by different biochemical tests. All strains produced bubbles as indicators of carbon dioxide production in Durham tubes. The maximum hallow on Congo red staining was shown by CA2, CG2, as 54, 40 mm with cellulolytic index 16.3 and 19. Cellulose degradation was evaluated as light pink to maroon color in triphenyl tetrazolium in all strains except CA4 and CB1. Cellulose (2%) added medium was provided to the isolated strains for the period of 10 days to allow fermentation. CG2 and CA2 yielded maximum ethanol as 0.42±0.005 and 0.43±0.011 (g of ethanol/ g of reducing sugar consumed), respectively. Their percent fermentation efficiency was observed as 79.71±0.059% and 75.58±0.011% correspondingly. All strains showed cellulose activity, and the maximum was seen in CA2 and CG2 as 0.265±0.05, 0.27±0.011 μmol/min/L. Molecular characterization suggested that the CA2 and CG2 strains were Bacillus manliponesis CA2 and Bacillus sp. CG2 (Accession Nos. ON324120 and OM974175). This study elaborates on the capability of bacteria to produce bioethanol by degrading cellulose.
Awake surgery in neurooncology. Part 1. Anesthesia features, selection of patients, method’s advantages and drawbacks
Authors: Dmitriev A. Yu. , Sinkin M. V. , Solodov A. A. , Dashyan V. G. 
Published: February 2024

To reduce patient’s discomfort during awake surgery convenient patient’s position on operation table is applied, comfort temperature and close contact to psychologist are supported. Anesthesiologic features of awake surgery include regional and conduction anesthesia of scalp nerves, light sedation, attentive control over air ways and dural infiltration with anesthetics. Keeping patient’s consciousness during surgical approach increases reliability of intraoperative tests but demands more thorough anesthesia and control over patient’s condition.Neuromonitoring in awake patient increases extent of gliomas’ resection and decreases risk of permanent neurological disorders.Risks of awake surgery are devided into respiratory, neurological, cardiological and psychological. Intraoperative seizures arise in 3–12 % of cases.Most of the patients rate awake surgery positively and agree to repeated similar operations.