bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gantry-free cone-beam CT arthrography for diagnosis of scapholunate ligament injuries: accelerating the preoperative work-up in acute wrist trauma
Authors: Luetkens Karsten Sebastian , Kunz Andreas Steven , Paul Mila Marie , Hölscher-Doht Stefanie , Huflage Henner , Heidenreich Julius Frederik , Müller Lukas , Bley Thorsten Alexander , Schmitt Rainer , Grunz Jan-Peter 
Published: February 2025

Abstract

Objective
Combining fluoroscopy and high-resolution cone-beam CT (CBCT) in a multipurpose scanner without a conventional gantry holds the potential for time-saving in musculoskeletal interventions. This study investigated the performance of gantry-free CBCT arthrography in patients with suspected scapholunate ligament (SLL) tears.

Materials and methods
Fifty-five patients (29 men, 46.0 ± 15.3 years) who underwent preoperative gantry-free CBCT arthrography between June 2021 and March 2024 were analyzed retrospectively. Three radiologists assessed CBCT arthrograms for tears of the palmar and dorsal SLL segments. Surgical reports served as the reference standard for calculating indicators of diagnostic accuracy. Interreader agreement was tested by computing Krippendorff α. Radiation dose and examination time were recorded.

Results
Tears of the palmar and dorsal SLL segment were recorded in 25 (45%) and 6 patients (11%), respectively. CBCT arthrography facilitated good sensitivity (range for all readers: 84–92%) and excellent specificity (93–97%) in the assessment of the palmar SLL. For the dorsal SLL, sensitivity (83–100%) and specificity (96–98%) were even higher. Substantial agreement was determined for both the palmar (α = 0.83, 95% CI: 0.74–0.90) and dorsal SLL (0.84, 0.70–0.95). The mean volume CT dose index for CBCT arthrography was 3.2 ± 1.4 mGy. Not requiring patient repositioning, the median time between fluoroscopy-guided contrast injection and CBCT was 3:05 min (2:31–3:50 min).

Conclusion
Gantry-free CBCT arthrography allows for excellent accuracy in the preoperative diagnosis of SLL tears with low radiation dose. The ability to alternate between fluoroscopy and CBCT without repositioning facilitates a “one-stop-shop” approach with short examination time.

Key Points

Question

Performing fluoroscopy-guided arthrography and high-resolution cone-beam CT without patient repositioning appears advantageous for the preoperative work-up of distal radius fractures with concomitant scapholunate ligament injuries.

Findings

Gantry-free cone-beam CT arthrography allowed for short examination times and high diagnostic accuracy for either segment of the scapholunate ligament (89–98% versus surgery).

Clinical relevance

Preoperative assessment of scapholunate instability influences treatment since surgeons can reduce radius fractures and perform osteosynthesis via a dorsal portal to simultaneously stabilize the scapholunate compartment or use an additional dorsal access route for ligament suture and transfixation.
Vitamin and dietary supplements are not associated with total or cardiovascular mortality in Switzerland: the CoLaus|PsyCoLaus prospective study
Authors: Lourenço Rosa , Vidal Pedro-Marques 
Published: February 2025

Abstract

Purpose
Vitamin-mineral and dietary supplements (VMDS) are taken by a large fraction of the population. Whether their long-term consumption impacts mortality and cardiovascular disease (CVD) has seldom been studied.

Methods
Prospective study from a population-based cohort from Lausanne, Switzerland. Participants were categorized as non-users (no consumption at baseline and first follow-up), persistent users (consumption at baseline and follow-up), and occasional users (consumption either at baseline or follow-up). Incidence of CVD and of total mortality was assessed after the first follow-up.

Results
Data from 4261 participants (57.4 ± 10.4 years, 55% females) was used. Median follow-up was 9 years (interquartile range 7.0–9.2) After multivariable analysis, no association was found between VMDS use and total mortality: hazard ratio and (95% confidence interval) 0.95 (0.71–1.28) and 0.83 (0.55–1.26) for occasional and persistent consumers, respectively, CVD mortality: 1.00 (0.47–2.11) and 1.30 (0.53–3.18), or CVD events: 0.96 (0.72–1.27) and 0.95 (0.64–1.42). Similar findings were obtained after inverse probability weighting, using only vitamin-mineral supplement users, or considering only participants at baseline. When CVD events were split into coronary heart disease (CHD) or stroke, persistent use of VMDS was associated with a higher risk of CHD in females: 3.12 (1.52–6.41), p = 0.002, but not in males, 0.25 (0.03–1.82), p = 0.171, p for interaction < 0.05. No association was found between VMDS use and incidence of stroke in both sexes.

Conclusion
We found no association between vitamin and dietary supplement use and total or CVD mortality, or CVD events. The higher risk of CHD for persistent use in females should be further explored.
Traumatic lumbosacral instability: part 2—indications and techniques for surgical management
Authors: Lindtner Richard A. , Krappinger Dietmar , Lindahl Jan , Bellabarba Carlo 
Published: February 2025

Abstract
Traumatic lumbosacral instability (TLSI) refers to a traumatic disruption of the axial skeleton at the level of the lumbosacral motion segment and/or sacrum, resulting in mechanical separation of the caudal spinal column from the posterior pelvic ring. Managing TLSI and its four underlying conditions poses unique challenges among spinal and pelvic injuries. This second part of a two-part series focuses on treatment strategies and decision making in TLSI, with an emphasis on surgical stabilization techniques. The primary objectives of this article are to: (1) elucidate factors influencing clinical decision-making, (2) synthesize current treatment options for the injury patterns underlying TLSI, and (3) briefly outline expected outcomes and complications.
Sex-specific differences in recurrence and progression following cytostatic intravesical chemotherapy for non-muscle invasive urothelial bladder cancer (NMIBC)
Authors: Schneidewind Laila , Kiss Bernhard , Neumann Thomas , Kranz Jennifer , Zengerling Friedemann , Graf Sebastian , Graser Annabel , Uhlig Annemarie 
Published: February 2025

Abstract

Purpose
To systematically analyze gender-specific differences in recurrence-free survival (RFS), progression-free survival (PFS), cancer-specific survival (CSS), and overall survival (OS) as well as adverse events and quality of Life (QoL) as secondary aims in NMIBC patients undergoing cytostatic intravesical chemotherapy.

Methods
A systematic review and meta-analysis were conducted on studies published between 1976 and 2024, following PRISMA guidelines. MEDLINE, Embase and Cochrane Library were used as literature sources. No restrictions were made concerning language, study region or publication type. Data from 12 studies encompassing 1,527 patients were analyzed. Outcomes were assessed using random-effects models, with gender as a primary variable of interest. A risk of bias assessment was done using the ROBINS-I tool or RoB2 as appropriate.

Results
The pooled analysis demonstrated no statistically significant gender-specific differences in RFS (HR = 1.0625, 95% CI 0.8094–1.0526) or PFS (HR = 1.0861, 95% CI 0.7038–1.6760). Data on CSS and OS were insufficient for meaningful conclusions. Two included studies analyzed in univariate or multivariate regression gender as risk factor for recurrence or progression, but gender was not a significant risk factor. Adverse events and QoL outcomes were notably underreported, with no gender-specific data available.

Conclusions
While this study found no significant gender-based differences in NMIBC outcomes following intravesical chemotherapy, the findings are limited by the small number of studies, underrepresentation of women, and inconsistent reporting of critical outcomes. Future research should prioritize gender-focused analyses and explore the molecular and genetic basis of potential differences to inform precision medicine and equitable care.
Adaptafood: an intelligent system to adapt recipes to specialised diets and healthy lifestyles
Authors: Morales-Garzón Andrea , Gutiérrez-Batista Karel , Martin-Bautista Maria J. 
Published: February 2025

Abstract
This paper presents AdaptaFood, a system to adapt recipes to specific dietary constraints. This is a common societal issue due to various dietary needs arising from medical conditions, allergies, or nutritional preferences. AdaptaFood provides recipe adaptations from two inputs: a recipe image (a fine-tuned image-captioning model allows us to extract the ingredients) or a recipe object (we extract the ingredients from the recipe features). For the adaptation, we propose to use an attention-based language sentence model based on BERT to learn the semantics of the ingredients and, therefore, discover the hidden relations among them. Specifically, we use them to perform two tasks: (1) align the food items from several sources to expand recipe information; (2) use the semantic features embedded in the representation vector to detect potential food substitutes for the ingredients. The results show that the model successfully learns domain-specific knowledge after re-training it to the food computing domain. Combining this acquired knowledge with the adopted strategy for sentence representation and food replacement enables the generation of high-quality recipe versions and dealing with the heterogeneity of different-origin food data.
Perioperative complications in spinal trauma patients: does timing matter?
Authors: Adegeest Charlotte Y. , Hilke Cas J. , de Ruiter Godard C. W. , Arts Mark P. , Vleggeert-Lankamp Carmen L. , Martin Raoul D. , Peul Wilco C. , ter Wengel Paula Valerie 
Published: February 2025

Abstract

Background
Early surgery in traumatic spinal fracture treatment may facilitate prompt mobilization, encountering affiliated complications. However, the safety and the benefits of early surgery are being questioned in spinal trauma patients. Therefore, the objective of this retrospective study is to investigate the effect of surgical timing on perioperative complications in these patients.

Methods
Spinal trauma patients who underwent surgery between 2010 and 2020 in two Dutch Level-I trauma centers were included retrospectively and divided into an early (< 24 h), late (between 24 and 72 h) and delayed (> 72 h) surgical cohort. The primary outcome was the occurrence of peri-operative complications. Besides surgical timing, trauma and patient-specific factors were also analyzed as potential risk factors for the occurrence of complications.

Results
A total of 394 patients were included, of whom 149 received early, 159 late and 86 delayed surgical treatment. The occurrence of perioperative complications was significantly associated with age, body mass index, comorbidities, ASA grade 3 and 4, spinal cord injury (SCI), AO Spine type C injury, additional chest injury, and surgical delay. A multivariable analysis showed that age, ASA category, AO Spine classification and SCI were significantly associated with perioperative complications. Moreover, a subsequent analysis in non-SCI patients demonstrated an association between perioperative complications and delayed surgery.

Conclusions
In this study, delayed surgical treatment is potentially associated with more perioperative complications compared to early surgery in non-SCI patients. Other possible risk factors for the occurrence of perioperative complications may be older age, ASA 3 and 4, AO spine C injury and SCI.
Modeling commodity price co-movement: building on traditional time series models and exploring applications of machine learning algorithms
Authors: Kozian Luca L. , Machado Marcos R. , Osterrieder Joerg R. 
Published: February 2025

Abstract
In this study, we explore the efficacy of various methodologies and co-movement measures for modeling the co-movement of cross-commodity prices, using macroeconomic variables. Applying Vector Autoregression (VAR), VAR with exogenous variables (VARX), multiple regressions, and Random Forest regressions, alongside Pearson correlations and Gerber statistics, we analyze the price co-movement of 20 key commodities over the period from mid-2003 to early 2023. Our results reveal that VAR and VARX models notably outperform Random Forests and multiple regressions, achieving

$$R^2$$

R
2

values of up to 89%. Although Random Forests marginally outperform multiple regressions, they are still inferior to VAR-based approaches. Furthermore, we observe that the inclusion of Gerber statistics (differently from the Pearson correlation metric) enhances the effectiveness of VAR and VARX models, while their influence on Random Forests and multiple regression models remains indeterminate. This research contextualizes and contributes to the existing literature on commodity price dynamics, providing insights into the relative strengths of various modeling approaches and setting the stage for future methodological advancements, especially in the applications of Machine Learning (ML) in the field.
How sea ice affects edge waves in the Sea of Okhotsk
Authors: Kovalev Peter D. , Kovalev Dmitry P. , Zarochintsev Vitaly S. , Squire Vernon A. 
Published: February 2025

Abstract
Long-term observations, which were collected in the Sea of Okhotsk coastal zone under open-water conditions and at times when the sea was ice-covered from mid-January to mid-March 2022, are interpreted. The project augments preceding work using three synchronously-recording, seafloor-mounted, pressure transducers sampling at 1 Hz to acquire time series of inshore wave oscillations. Units are deployed nearer to the shore and closer together than was done during the previous studies. Spectral analyses of open-water sea level oscillations perpendicular to the coast reveal a wide band of energy, suggestive of a propagating edge wave at about 5-min period with an offshore-to-inshore gain up to 1.5. Similar wave characteristics occur alongshore. Intriguingly, the peak edge wave period at 5 min migrates to 6–7 min when the sea becomes covered with ice, and narrower bands at periods from 0.5 to about 3 min emerge. Other period ranges also appear to be affected by the onset, presence and eventual disintegration of sea ice. Whilst a shift of the dominant edge wave period can be attributed to changes in spectral refraction arising from the incoming swells being low-pass filtered by sea ice, because of the observed tidal signal it is speculated in this case that the observed period adjustment and attendant expansion of bandwidth may also be associated with instability around the fundamental frequency. The potential for edge wave solitons to exist is explored.
Deep learning initialized compressed sensing (Deli-CS) in volumetric spatio-temporal subspace reconstruction
Authors: Schauman S. Sophie , Iyer Siddharth S. , Sandino Christopher M. , Yurt Mahmut , Cao Xiaozhi , Liao Congyu , Ruengchaijatuporn Natthanan , Chatnuntawech Itthi , Tong Elizabeth , Setsompop Kawin 
Published: February 2025

Abstract

Object
Spatio-temporal MRI methods offer rapid whole-brain multi-parametric mapping, yet they are often hindered by prolonged reconstruction times or prohibitively burdensome hardware requirements. The aim of this project is to reduce reconstruction time using deep learning.

Materials and methods
This study focuses on accelerating the reconstruction of volumetric multi-axis spiral projection MRF, aiming for whole-brain T1 and T2 mapping, while ensuring a streamlined approach compatible with clinical requirements. To optimize reconstruction time, the traditional method is first revamped with a memory-efficient GPU implementation. Deep Learning Initialized Compressed Sensing (Deli-CS) is then introduced, which initiates iterative reconstruction with a DL-generated seed point, reducing the number of iterations needed for convergence.

Results
The full reconstruction process for volumetric multi-axis spiral projection MRF is completed in just 20 min compared to over 2 h for the previously published implementation. Comparative analysis demonstrates Deli-CS’s efficiency in expediting iterative reconstruction while maintaining high-quality results.

Discussion
By offering a rapid warm start to the iterative reconstruction algorithm, this method substantially reduces processing time while preserving reconstruction quality. Its successful implementation paves the way for advanced spatio-temporal MRI techniques, addressing the challenge of extensive reconstruction times and ensuring efficient, high-quality imaging in a streamlined manner.
HIV Testing and PrEP Use Among Trans and/or Non-binary Participants in the TASG Study, a Participatory Study in Germany
Authors: Koppe Uwe , Hamm Jonas A. , Spurgat Chris , Hahne Alexander , Saalfeld Robin K. , Garcia Manuel Ricardo , Bremer Viviane , Pöge Kathleen ,   for the TASG study group, Schlögl Teo , Appenroth Max Nicolai , Fink Né , Voß Heinz-Jürgen , Schuler Christoph , Plaßmann Kuem-Song , Rentzsch Silvia 
Published: February 2025

Abstract
HIV testing and pre-exposure prophylaxis (PrEP) are recommended in Germany for individuals at increased HIV risk. However, data on HIV testing, PrEP use, and PrEP knowledge among trans and non-binary people are limited. We analysed data from the ‘Sexuelle Gesundheit in trans und nicht-binären Communitys’ (TASG) study, a participatory study on HIV/STI and sexual health among trans and non-binary people in Germany. The study was designed, promoted, and analysed with active involvement of community members. Participants were invited to complete an anonymous online survey between 1 March and 1 July 2022. The outcomes included HIV testing within the last 5 years, PrEP use, and PrEP-specific knowledge. Predictors for HIV testing were identified using a bootstrap stepwise selection procedure. Among 2468 HIV-negative participants with information on potential HIV risks, 21.5% had potential needs for HIV testing and PrEP. Of these, only 44.3% (208/470, missing: 60) reported testing for HIV within the last 5 years. Older participants, those living in larger cities, and those with higher education levels were more likely to have tested for HIV. Additionally, only 8.3% (38/459, missing: 71) reported ever using PrEP. Among 451 participants with potential PrEP needs (missing: 79), only 57.4% knew at least one of three key PrEP-related facts at the time of the survey. Our findings highlight substantial gaps in HIV testing and prevention among trans and non-binary individuals in Germany with potential needs for these services. Reducing barriers to testing and prevention is essential to enable broader access to these critical services.
GenomicSEM Modelling of Diverse Executive Function GWAS Improves Gene Discovery
Authors: Perry Lucas C. , Chevalier Nicolas , Luciano Michelle ,   CHARGE Consortium
Published: February 2025

Abstract
Previous research has supported the use of latent variables as the gold-standard in measuring executive function. However, for logistical reasons genome-wide association studies (GWAS) of executive function have largely eschewed latent variables in favour of singular task measures. As low correlations have traditionally been found between individual executive function (EF) tests, it is unclear whether these GWAS have truly been measuring the same construct. In this study, we addressed this question by performing a factor analysis on summary statistics from eleven GWAS of EF taken from five studies, using GenomicSEM. Models demonstrated a bifactor structure consistent with previous research, with factors capturing common EF and working memory- specific variance. Furthermore, the GWAS performed on this model identified 20 new genomic risk loci for common EF and 4 for working memory reaching genome-wide significance beyond what was found in the constituent GWAS, together resulting in 29 newly mapped EF genes. These results help to clarify the underlying genetic structure of EF and support the idea that EF GWAS are capable of measuring genetic variance related to latent EF constructs even when not using factor scores. Furthermore, they demonstrate that GenomicSEM can combine GWAS with divergent and non-ideal measures of the same phenotype to improve statistical power.
Where Is the Parent’s Voice? A Meta-Synthesis of Parental Experiences of Video Feedback Parenting Interventions
Authors: Wan Ming Wai , Johal Tarendeep. K. , Wittkowski Anja 
Published: February 2025

Abstract
Video-aided feedback (VF) is a well-evidenced intervention technique to enhance the relationship between a parent and their young child. While parental acceptability is foundational to engagement and intervention efficacy, the parent’s perspective is only now emerging as a valued consideration when evaluating VF-based interventions. This systematic review metasynthesised qualitative research on the experiences of primary caregivers with a young child (primarily 0–30 months) of participating in a VF parenting intervention. A search of nine databases yielded 17 studies (10 published since 2020) involving parents who had participated in range of VF-focussed programmes. Thematic synthesis identified six themes: (1) Getting past the fear and discomfort: Being ‘good enough’ and ‘doing the right thing’; (2) The power of video: “I had never really noticed that before‟ (with two subthemes: video as validation and for seeing child behavioural intentionality; video as an agent for change); (3) The practitioner’s skill and role in creating a safe space; (4) The approach was too intangible, inflexible, positive, unclear; (5) When the intervention is over: Positive change and generalisation; (6) Parental engagement and involvement: Barriers and enhancements. While most parents reported experiencing a range of interpersonal and intrapersonal benefits from taking part in a VF parenting intervention, having to overcome initial strong negative and uncomfortable feelings were an important part of the journey. Some parents could not see the value of the approach or did not perceive the intervention to meet their needs. Insights into parental experience are complementary to outcome-based evaluations. However, biased design (e.g., only one study included intervention non-completers) and variable study quality need addressing in future studies. Implications for practice are discussed.
Do Foreign Service Providers Simply Ignore the EU Consumer Law? An Empirical Study of 100 Online Terms of Service
Authors: Pałka P. , Porębski A. , Pałosz R. , Wiśniewska K. 
Published: February 2025

Abstract
This article reports the results of an empirical study conducted on 100 online terms of services offered in the EU. It documents the prevalence of (potentially) unfair clauses in these contracts and discusses the outcomes of the inferential statistical analysis performed to discover any patterns of this widespread incompliance. It shows that contracts accompanying services with the main headquarters outside of the EU are significantly more likely to contain unfair terms than those originating from the EU. The article offers several possible explanations of this phenomenon, including the features of the corporations and the particularities of the European consumer law enforcement structure. Based on these findings, we offer several possible policy interventions. These include closer scrutiny of corporations from outside the Union, operationalisation of the tools for automated detection of unfair clauses, and potential legal reform, including the possibility of leveraging the enforcement structure put in place by the Digital Services Act.