bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Microcrystalline Cellulose on The Structure and Properties of PVDF/1-Allyl-3- methylimidazolium Chloride Composite Materials
Authors: Liu Kun , Wang Haijun , Zhao Mengen , Wu Yao , Yuan Chunlei , Yan Chao , Jiang Qinglong 
Published: October 2023

Abstract
In this study, the solution-casting method was utilized to prepare poly(allylidene fluoride)(PVDF)/1-allyl-3-methylimidazolium chloride ([AMIM]Cl)/microcrystalline cellulose (MCC) composite films at 100°C. Besides, investigations were conducted on the synergistic effect of [AMIM]Cl and MCC on the crystalline phase of PVDF and the dielectric property of the composites. The results show that the presence of [AMIM]Cl induced the formation of β-PVDF due to the ion-dipole interactions and increased the permittivity and dielectric loss. In the PVDF/[AMIM]Cl/MCC ternary composites, [AMIM]Cl significantly reduced the size of MCC and promoted its dispersion, which led to the further marked increase in permittivity and decrease in dielectric loss. With the addition of 7% [AMIM]Cl and 10% MCC, the permittivity rose to 135.15 while the loss decreased to only 0.71. Therefore, this work provides an efficient strategy to prepare PVDF-based composites with high permittivity and low dielectric loss, which holds sound promise for the development of high-performance materials in electronic devices and dielectric applications.
Indirect Organogenesis of Platycladus Orientalis L.
Authors: Lucena-Soriano Luis , Ocaña Ana María Fernández 
Published: October 2023

Abstract
In conifer species vegetative propagation has many limitations, from low germination rates to the difficulty of rooting explants. Plant in vitro culture has long been used for multiplication, genetic improvement and conservation of elite traits. In this work it has been determined the influence of several parameters on the in vitro culture of Platycladus orientalis L.: the culture media, the type of explant, light/dark growth conditions and vernalisation period, specifically, on three different phases of development: germination, callus induction and indirect organogenesis. The best explant for callus induction was the cotyledon and the ideal medium for its culture was Murashige-Skoog under lighting conditions. In the case of indirect organogenesis, the better-differentiated explants grew up with light and LePoivre medium. In germination, the vernalisation of seeds during two months subjected to 4ºC had a positive influence. The best medium, which produced the greatest number of roots and the greatest length, was Murashige-Skoog. Also, it has determined the important role of seed coats in germination.
Demand for Cardiopulmonary Resuscitation and Bleeding Control Skills Training in an Urban Region: A Feasibility Review of a Community Engagement Effort
Authors: Hoops Katherine , Bedner Ashley , Kemper Emily , Aksamit Deborah , O’Brien Caitlin , Johnson Marcie K. , Stewart Rosalyn W. , Maydan Daniella D. , Hailey-Fair Kimberly , Galiatsatos Panagis 
Published: October 2023

Abstract
In maintained, bi-directional medical-community collaborations, partnering social organizations may request teachings for health skills from their respective health system in an immediate moment-in-time due to certain contextual factors that demand it. One such health skill is cardiopulmonary resuscitation (CPR), a valuable competency that may allow a community member to save the life of their peer, and which is often requested due to personal experiences by members in the respective social network. Similarly, communities, especially those affected by violence, have sought out hemorrhage control skills training which can help to control life-threatening bleeding. In this community engagement feasibility review, we evaluate the infrastructure warranted to implement bystander CPR and bleeding control skills training to diverse social organizations in an urban region over a 9-month period. Further, we review the necessary variables to sustain such an effort, for both the health system as well as the partnering communities.
IMPeTUs parameters correlate with clinical features in newly diagnosed multiple myeloma
Authors: Xu Shuaishuai , Liu Songtao , Guo Huimin , Chen Wenkun , Yao Shuzhan 
Published: October 2023

Abstract
Background
To investigate the correlations between IMPeTUs-based 18F-FDG PET/CT parameters and clinical features in patients with newly diagnosed multiple myeloma (MM). 18F-FDG PET/CT in newly diagnosed MM patients were retrospectively analysed according to the IMPeTUs criteria. We correlated these PET/CT parameters with known clinically relevant features, bone marrow plasma cell infiltration rate (BMPC) and the presence of cytogenetic abnormalities.
Results
A total of 108 patients (64 males, 44 females; mean age, 59.7 ± 9.7 years; range, 34–83 years) with newly diagnosed MM who had undergone 18F-FDG PET/CT at our hospital were included in this study. Bone marrow metabolic state correlated with the most clinical features including FLC ratio (p = 0.036), involved FLC (p = 0.03), β2M (p = 0.001), calcium (p = 0.014), creatinine (p < 0.001), cytogenetic abnormalities (p = 0.033), and showed a positive correlation with ISS III (p = 0.002) and R-ISS III (p = 0.003). Importantly, there was no significant correlation between BM metabolic state and the level of BMPC (p = 0.102). Hypermetabolism in limbs and ribs conformed a positive correlation with the levels of β2M (p = 0.046), calcium (p = 0.044), and R-ISS (p = 0.01). Metabolic activity of the hottest lesion = 5 correlated with higher level of CRP (p = 0.038) and higher incidence of DS III (p = 0.006).
Conclusions
Several IMPeTUs-based PET/CT parameters showed significant correlations with clinical features reflecting disease burden and biology, suggesting that this new criteria can be used in the risk stratification in MM patients.
Tracking the long-term limnological impacts of silver mining near Keno City (Yukon, subarctic Canada)
Authors: Jones Evan A , Michelutti Neal , Would Jamie A , Pisaric Michael FJ , Smol John P 
Published: October 2023

Abstract

Mining in Northern Canada has been known to cause major environmental repercussions; however, monitoring data are scarce or non-existent. Here, we use a multi-proxy (metals, bioindicators, pigments) paleolimnological approach to track the impacts of mining activity near Keno City, on the traditional land of the First Nation of Na-Cho Nyäk Dun, in central Yukon (Canada). Silver was discovered in the early-1900s, primarily on or between two hills (Galena Hill and Keno Hill) and intensive mining has taken place ever since, with brief hiatuses dependent to ore prices and ownership of the claims. Christal Lake, a shallow site located in the valley between both hills, lies nearby many historical and current mines, and was once the site of a processing mill. Geochemical data show elevated background concentrations of many metals and faithfully track known mining activity. Interestingly, background (pre-mining) sediment concentrations of arsenic, cadmium, and zinc were all elevated above the Canadian Sediment Quality Guidelines for the Protection of Aquatic Life, reflecting the high concentrations of these elements in the local catchment. These, and other metal(loid)s, increased and peaked in sedimentary concentration after ca. 1920s, when intensive mining began. Sedimentary chlorophyll-a concentrations plummeted with the rise of metal concentrations, although increased again slightly in more recent sediments, perhaps reflecting the decline in recent metal inputs and reclamation of historic mine sites. Meanwhile, subfossil diatom assemblages were dominated by small benthic Fragilaria sensu lato taxa, whose assemblage composition only changed subtly with mining (similar to other shallow, non-acidified sites in Norilsk, Siberia). There was no biological evidence of acidification, likely due to the neutralizing effect of the carbonate-rich catchment. Cladoceran subfossils were only present in very low numbers throughout the core, reflecting both the shallow nature and high background metal concentrations in the lake. Collectively, these data show the long-term impacts of silver mining in this subarctic environment.
Haemoglobin, albumin, lymphocyte, and platelet (HALP) score is a useful predictor of prognosis after hepatectomy for hepatocellular carcinoma: a retrospective, propensity score matching cohort study
Authors: Hashimoto Kazuaki , Kanno Hiroki , Sakai Hisamune , Miyazaki Daiki , Fukutomi Shogo , Arai Shoichiro , Goto Yuichi , Akashi Masanori , Isobe Taro , Mori Naoki , Ishibashi Nobuya , Fujita Fumihiko , Hisaka Toru 
Published: October 2023

Abstract
Background
The haemoglobin, albumin, lymphocyte, and platelet (HALP) score is an immune-nutritional assessment score that is a prognostic indicator for several malignant tumours. This study aimed to investigate its prognostic value in patients who underwent hepatectomy for hepatocellular carcinoma.
Methods
The data of 685 patients with hepatocellular carcinoma who underwent hepatectomy at Kurume University between 2006 and 2021 were retrospectively analysed. The patients were classified into high and low HALP score groups based on a cut-off HALP score determined using a receiver operating characteristic curve. To minimise bias, 1:1 propensity score matching was performed. Kaplan–Meier curves were used to estimate survival time, and data were evaluated using the log-rank test. Univariate and multivariate analyses were performed using Cox hazard or logistic regression models for assessing survival time and postoperative outcomes, respectively.
Results
Low HALP scores were significantly associated with poor overall survival (P = 0.0061). Univariate and multivariate analyses revealed that HALP score independently predicted overall survival (P = 0.005). However, the HALP score was not significantly related to recurrence-free survival or postoperative outcomes.
Conclusions
The HALP score is a simple, inexpensive tool for predicting prognosis after hepatectomy for hepatocellular carcinoma.
Effect of using Nano-particles of Magnesium Oxide and Titanium Dioxide to Enhance Properties of Hip Joint Bone Cement
Authors: Gamal Safaa , Mikhail Mina , Salem Nancy , EL-Wakaad Mohamed Tarek , Abdelbaset Reda 
Published: October 2023

Abstract
This paper studies the effect of adding Magnesium Oxide (MgO) and Titanium Dioxide (TiO2) nano particles to enhance the properties of hip joint bone cement. Related to previous work of enhanced bone cement properties by using MgO and TiO2, samples of composite bone cement using three different ratios (0.5%, 1% and 1.5%) w/w of MgO and TiO2 were prepared to calculate the best enhancement ratio. Hardness, compression and bending tests were calculated to check the mechanical properties of pure and composite bone cement. The surface structure was studied using Fourier transform infrared spectroscopy (FTIR) and Field emission scanning electron microscopy (FE-SEM). Setting temperature, porosity and degradation were calculated for each specimen ratio to check values match with standard range of bone cement. Results show remarkable improvement for mechanical and surface structure properties with acceptable changes in FTIR, setting temperature, degradation percentage and bending test relative to pure bone cement.
Endovascular treatment of delayed arterial hemorrhage following surgery for cholangiolithiasis
Authors: Wang Xiangdong , Zhou Jing , Ge Naijian , Yang Yefa 
Published: October 2023

Abstract
Objectives
To retrospectively evaluate the safety and efficacy of endovascular treatment (EVT) of delayed arterial hemorrhage (DAH) following surgery for cholangiolithiasis.
Methods
All patients who underwent EVT to manage DAH after surgery for cholangiolithiasiswere enrolled in this study. Demographic, laboratory, angiographic, and clinical follow-up data were collected and analyzed.
Results
15 patients were enrolled. The origins of bleeding were the right hepatic artery (RHA，n=6), the RHA branch (n=3), the gastroduodenal artery (GDA, n=2) and the GDA branch (n=4). Embolization and covered stents implantation were performed in 11 patients and 4 patients, respectively. The technical success rate was 100.0% (15/15) and the clinical success rate was 66.7% (10/15). For rebleeding patients, injured artery was identified and successfully occluded by a second angiography in 2. One patient had acute hepatic failure and recovered subsequently. The overall survival rate was 86.7% (13/15) during the follow-up of 90 days after EVT.
Conclusion
EVT of DAH after surgery for cholangiolithiasis is effective and safe. Angiography is also a valuable treatment alternative for rebleeding patients who have technical successfully been ceased the bleeding at the previous EVT.
Harnessing the Potential of Pigeonpea and Maize Feedstock Biochar for Carbon Sequestration, Energy Generation, and Environmental Sustainability
Authors: Kumar Nallagatla Vinod , Sawargaonkar Gajanan , Rani C. Sudha , Pasumarthi Rajesh , Kale Santhosh , Prakash T. Ram , Triveni S. , Singh Ajay , Davala Moses Shyam , Khopade Rohan , Karthik Rayapati , Venkatesh Bathula , chandra Mandapelli Sharath 
Published: October 2023

Abstract
Crop residues in agriculture pose disposal challenges and contribute to air pollution when burned. This study aims to use pigeonpea stalks and maize biomass to produce biochar. Biochar can serve as a soil amendment for carbon sequestration and as an alternative fuel source. Pyrolysis were conducted at different temperatures (i.e., 400, 500, and 600°C) to examine the effects on physicochemical properties, fuel characteristics, and energy consumption. Higher temperatures resulted in decreased biochar yield, volatile matter, and O/C and H/C atomic ratios, while ash content and essential nutrients increased. The composition of the biomass significantly affected the yield, with PPS yielding more biochar than maize biomass at the same pyrolysis temperature. The biochar derived from both PPS and maize biomass met the essential quality criteria for carbon sequestration in soil, as established by the European Biochar Certificate (EBC) and the International Biochar Initiative (IBC). The biochar obtained through pyrolysis at 400°C demonstrated superior characteristics compared to biochar produced at other temperatures. It exhibited a higher biochar yield, with approximately 84.60% for pigeonpea and 64.85% for maize fixed carbon content. Additionally, the energy retention efficiency was higher, reaching 67.33% for pigeonpea and 42.70% for maize-derived biochar at a pyrolysis temperature of 400°C. The fixed carbon recovery efficiency was also notable at around 200.44% for PPS and 142.37% for maize biochar. Furthermore, the higher heating value (HHV) was approximately 30.75 MJ kg-1 for both, indicating their suitability as alternative solid fuels. A significant CO2 reduction potential of 84 CO2 eq kg−1 and 55 CO2 eq kg-1 was observed for pigeonpea and maize biochar, respectively. Hence, biochar is a promising and effective option for carbon sequestration, offering environmental benefits.
Effect of ABCB1C1236T gene polymorphism on analgesic effects of sufentanil and morphine in patients with femoral fracture after surgery
Authors: Qin xiaofeng , huang qiurui , An Jianzhong , wang chen , Xu Fuqi , Qiao Shigang 
Published: October 2023

Abstract
Objective This study was aimed to investigate the impact of the ABCB1C1236T gene polymorphism on the analgesic efficacy of morphine combined with sufentanil in patients undergoing surgery for femoral fracture.
Methods A total of 400 patients with femoral fracture (FF) were assigned to either the morphine group or the non-morphine group by random number table method.. Prior to surgery, 2ml of venous blood was collected from all patients for genetic testing. Intravenous analgesia pumps were used after surgery.. In the morphine group, patients received an epidural injection of morphine hydrochloride (1.5ml) at the end of surgery, while patients in the non-morphine group received 0.9% normal saline (NS) solution (1.5ml). The C1236T gene polymorphism, as well as pain, nausea, and vomiting levels on days 1, 2, 3, and 7 after surgery, were assessed in both groups. Pain duration, the number of patient-controlled analgesia (PCA) compressions, and PCA pump fluid volume were also observed. Multiple linear regression analysis was employed to identify risk factors influencing pain levels on day 1 after surgery, using numerical rating scale (NRS) as the dependent variable.
Results A total of 369 patients were included, with 185 in the morphine group and 184 in the non-morphine group. In the morphine group, there were 90 cases of C/C genotype, 90 cases of C/T genotype, and 5 cases of T/T genotype. In the non-morphine group, there were 84 cases of C/C genotype, 76 cases of C/T genotype, and 24 cases of T/T genotype. The genotype frequencies in both groups conformed to the Hardy-Weinberg genetic equilibrium law. In the non-morphine group, patients with the CC genotype had lower NRS scores on day 1 compared to those with C/T and T/T genotypes (P < 0.05). No significant difference was found in NRS scores among the three genotypes in the morphine group (P > 0.05). Multiple linear regression analysis revealed that postoperative 1-day NRS scores were associated with the onset of postoperative pain and the ABCB1C1236T genotype (P < 0.05).
Conclusion The ABCB1C1236T gene polymorphism is a genetic factor influencing early postoperative pain in Han patients with FF. However, epidural administration of morphine can mitigate the impact of gene mutation on early analgesia caused by sufentanil.
Trial registration number：ChiCTR2300070098，the date of registration：2023-04-02
Graphical estimation of genetic characteristics for maize inbred lines and selection of superior hybrids by genotype by yield*trait (GYT) biplot
Authors: Hosseini Seyyed Mohammad Sadegh , Shiri Mohammadreza , Mostafavi Khodadad , Mohammadi Abdollah , Miri Seied Mehdi 
Published: October 2023

Abstract

This study aims to investigate (i) the genetic characteristics of nine maize inbred lines for the three traits namely grain moisture percent (GMP) at harvest time, days to physiological maturity (DPM), and grain yield (GY), (ii) the selection of superior hybrids based on the simultaneous selection of traits, and (iii) the ability of inbred lines to transfer genetic characteristics to the selected hybrids. Therefore, thirty-six hybrids resulting from their one-way diallel crosses were planted during the two crop years of 2020 and 2021 in a randomized complete block design with three replications. The genetic characteristics estimation and multiple trait selection were made by GGE biplot and GYT biplot procedure, respectively. Based on the results parents a, b, and h showed a negative general combining ability (GCA) and parent a showed the negative GCA. Moreover, parents a, b, and h exhibited a negative GCA positive could improve GMP, DPM, and GY, respectively, (ii) in the GYT biplot, yield-trait combinations indicated the most stable cultivars so that the crosses g×e and c×a were ranked as the best combination of GMP and DPM traits with grain yield, respectively and (iii) among the studied inbred lines, parent a had been able to transfer its desired characteristics such as earliness and high grain yield to its progeny. Applying biplot analyses to the multiple trait data revealed that The GYT biplot combines traits with yield and can facilitate the visual identification of the best genotypes.
Hyperglycemia does not explain the loss of function of apolipoproteinC1 on CETP activity in people with type 1 diabetes
Authors: Rouland Alexia , Gautier Thomas , Denimal Damien , Duvillard Laurence , Simoneau Isabelle , Rageot David , Vergès Bruno , Bouillet Benjamin 
Published: October 2023

Abstract
Background
HDL-associated apolipoproteinC1 (apoC1) has been demonstrated to be the main physiological cholesterol ester transfer protein (CETP) inhibitor. CETP promotes cholesterol ester and triglyceride exchanges between HDL and apolipoprotein-B containing lipoproteins, and augmented CETP activity has been shown to be associated with macrovascular complications in patients with type 1 diabetes (T1D). In a previous study, apoC1 lost its ability to inhibit CETP in patients with T1D and in vitro glycation of apoC1 impaired its ability to inhibit CETP. Thus, we hypothesize that hyperglycemia could be a factor implicated in the loss of the inhibitory effect of apoC1 on CETP in people with T1D.
We performed a prospective study in patients with uncontrolled T1D aiming to determine whether significant improvement of glycemic control could restore the inhibitory effect of apoC1 on CETP.
Methods
We studied 98 patients with uncontrolled T1D (HbA1c>9%) and no treatment that could influence lipoproteins metabolism at baseline, and 3 months after improvement of glycemic control by optimization of T1D therapy, and 92 normoglycemic normolipidemic control subjects. CETP activity was assessed by a radioactive method and plasma apoC1 levels were measured by ELISA in every participant. In addition, the different isoforms of apoC1 were determined by mass spectrometry in 20 patients with T1D and in 20 controls.
Results
After 3 months of treatment intensification, mean HbA1c was significantly reduced in patients with T1D (8.7±1.7 vs. 10.8±2, p<0.0001). CETP activity was not significantly modified after improvement of glycemic control. A significant negative association between plasma apoC1 and CETP activity was observed in controls (r=-0.0006, p= 0.013) but not in uncontrolled patients with T1D, at baseline and at 3 months. We did not find any glycated form of apoC1 using mass spectrometry in people with T1D (at baseline and at 3 months) compared with controls.
Conclusion
Hyperglycemia, in vivo, does not seem to be a major factor implicated in the loss of apoC1 ability to inhibit CETP activity observed in T1D. Other factors, such as qualitative abnormalities of lipoproteins, could be involved. Further studies are needed to better understand apoC1 dysfunction in T1D.
The effect of an active break intervention on nonspecific low back pain and musculoskeletal discomfort during prolonged sitting among young people - Protocol for a Randomized Controlled Trial
Authors: Plandowska Magdalena , Labecka Marta Kinga , Truszczyńska-Baszak Aleksandra , Płaszewski Maciej , Rajabi Reza , Makaruk Beata , Różańska Dorota 
Published: October 2023

Abstract
The study aims to evaluate the effectiveness of the active break program in reducing LBP and perceived musculoskeletal discomfort during prolonged sitting in young people with LBP. This will be a randomized controlled study. The participants will be recruited from students of a Bachelor’s course in Physical Education. The participants will be assigned to an experimental group (with an active break) and a control group. The primary outcomes will be average pain intensity (Visual Analogue Scale), functional disability (Oswestry Disability Index), and perceived musculoskeletal discomfort during prolonged sitting (Borg scale), and the Global Perceived Effect. The secondary outcome will be a Post-Intervention Questionnaire (5-item self-completed questionnaire). Our main research outcome – exercise protocols and interventions – will help to develop ergonomic recommendations for young people with LBP. Exercises and recommendations will be the basis for developing a proprietary preventive and therapeutic program, which will be implemented in selected educational institutions.