bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genetic and phenotypic trends for female fertility traits derived from service records of South African Holstein cattle
Authors: Kgari R.D. , Muller C.J.C. , Dzama K. , Makgahlela M.L. 
Published: February 2024

The objective of this study was to estimate breeding values (EBV) and genetic and phenotypic trends for female fertility traits derived from artificial insemination (AI) records. Data were collected from automated milk recording systems: 64464 records from 18 South African (SA) Holstein herds. Breeding values were estimated for heifer traits, i.e., age at first service (AFS), age at first calving (AFC), number of services per conception (SPCh); and for cow traits, i.e., calving to first service (CFS), number of days open (DO), number of services per conception (SPC), first service within 80 days post-partum (FS80d), and whether cows were confirmed pregnant within 100 days post-partum (PD100d) or within 200 days post-partum (PD200d) using THRGIBBSF90. Trends were estimated for the period 1984 to 2011. There was no clear trend on average breeding values for heifer traits. However, phenotypic trends for heifer traits showed a desirable downward trend, with a decrease of 0.14 and 0.13 months/year for AFS and AFC, respectively. Phenotypic trends for cow fertility traits appeared to increase at the rate 0.16 and 0.83 days/year for CFS and DO, respectively, with animals requiring 0.02 more services per year for SPC. The average EBV for binary traits FS80d, PD100d, and PD200d, showed no distinct trend. In general, there was no clear genetic and phenotypic trend for all traits defined. The trends that appeared to follow trait improvement could have been coincidental. Thus, efforts have to be made towards the improvement of heifer and cow fertility traits explored in this study
STRATEGI SCAFFOLDING DALAM KEMAMPUAN PEMECAHAN MASALAH SISWA SMP: A QUASI-EXPERIMENTAL STUDY
Authors: Srimuliati Srimuliati , Ulya Khairatul , Faisal Faisal , Anggraini Ria , Natasya Arsyifa Dian 
Published: February 2024

Menjadi problem solver adalah tujuan dari proses pembelajaran. Kemampuan ini dapat tercapai jika dilatihkan secara terus-menerus kepada siswa dengan menjadikan siswa menguasai berbagai kemampuan matematika. Salah satunya menguasai kemampuan pemecahan masalah matematis. Penelitian ini bertujuan untuk mengetahui apakah kemampuan pemecahan masalah matematis siswa yang diajarkan menggunakan strategi scaffolding lebih baik dari kemampuan pemecahan masalah siswa yang diajarkan secara konvensional. Quasi-experimental design digunakan sebagai rancangan dalam penelitian ini. Populasi dalam penelitian ini berjumlah 182 siswa dari SMPN 1 Tamiang Hulu, Aceh, Indonesia. Sedangkan sampel berjumlah 52 orang yang terdiri atas kelas eksperimen yaitu kelas VIII3 dan kelas kontrol, kelas VIII4. Teknik pengumpulan data menggunakan tes. Instumen yang digunakan yaitu soal tes kemampuan pemecahan masalah pada materi sistem persamaan linear dua variable berjumlah 5 soal dan berbentuk uraian. Hasil analisis data menunjukkan bahwa kemampuan pemecahan masalah siswa yang diajarkan dengan menggunakan strategi scaffolding lebih baik dibandingkan dengan kemampuan pemecahan masalah siswa yang diajarkan secara konvensial.AbstractTo be a problem solver is a learning instruction goal. This ability will achieve if students will be trained and learnt continuously to comprehend any mathematical skills. One of them is to have ability in problem solving skills. The aim of this study was to determine whether students’ problem-solving ability learnt by using the scaffolding strategy was better than students’ problem-solving ability learnt by using a conventional model or not. The quasi-experimental design was used as research design in this study. The population was a total 182 students of grade VIII of SMPN 1 Tamiang Hulu, Aceh Tamiang, Aceh, Indonesia. while the sample was 52 students which consist of two groups, namely class VIII3 as an experiment group and class VIII4 as a control group. The data was collected by using technique test. There were 5 questions about system of two linear equation was tested to measure the problem-solving ability of students. The results showed that students’ problem-solving ability learnt by using the scaffolding strategy is better than students’ problem-solving ability learnt by using a conventional model.
Pengaruh Content Marketing, Live Streaming dan Flash Sale terhadap Impulse Buying pada Pengguna Aplikasi Tiktok Shop di Surabaya: Studi pada Pengguna Tahun 2022-2023
Authors: Kurniawan Rafika Athiyah , Nugroho Rusdi Hidayat 
Published: February 2024

The presence of the internet is necessary for businesses, which makes it an important platform for modern sales and marketing. TikTok is often an efficient social media platform for online marketing. The purpose of this study is to determine the effect of content marketing, live streaming, flash sales on impulse buying in TikTok Shop application users in Surabaya. The type of research used is quantitative research. The population in this study were all TikTok Shop application users in 2022 to 2023 who live in Surabaya using a sample of 200 respondents. The sampling method used is non probability sampling and the sampling technique is purposive sampling. Multiple linear regression analysis was applied to analyze the data tested with SPSS version 25. The results of this study state that content marketing, live streaming, and flash sales have a significant effect on impulse buying. Content marketing, live streaming, and flash sale variables are valid and reliable variables. Simultaneously, the variables of content marketing, live streaming and flash have a positive and significant effect on impulse buying. Partially, content marketing and flash variables have a positive and significant effect on impulse buying. While the flash sale variable has no effect on impulse buying
Membangun Spiritualitas Kristiani Posmodern melalui Analogi Pembebasan Israel dari Mesir
Authors: Waoma Ken Jacks Gunawan , Rusmiyanto Andreas Danang 
Published: February 2024

This article examines the event of Israel's liberation from Egypt as a typology of the work of the Messiah and reflects it for Christian spirituality in the current post-postmodern era. This research investigates the parallels between the story of Israel's liberation and the teachings about the Messiah, highlighting symbolic meanings that can be applied analogically in the context of postmodern Christian life. This research uses descriptive and interpretative analysis methods with a hermeneutic approach. The typology of messianic work shown by the narrative of Israel's liberation from Egypt can become the foundation of Christian spirituality in the postmodern era.

Abstrak
Artikel ini mengkaji peristiwa pembebasan Israel dari Mesir sebagai tipologi karya Mesias dan merefleksikannya bagi spiritualitas kristiani di era posposmodern saat ini. Penelitian ini menyelidiki paralel antara kisah pembebasan Israel dan ajaran tentang Mesias, menyoroti makna simbolis yang dapat diaplikasikan secara analogis dalam konteks kehidupan Kristen posposmodern. Penelitian ini menggunakan metode analisis deskriptif dan interpretatif dengan pendekataan hermeneutik. Tipologi karya mesias yang ditunjukkan oleh narasi pembebasan Israel dari Mesir dapat menjadi fondasi spiritualitas kekristenan di era posmodern.
A Study of Agni, its Impact on Kostha Vaddhata (Constipation) and its Management With “Saghrita Lavanei Yukta Narau Annavagraham Peebet”
Authors: Sandh Krisan Kumar , Sahoo Manoj Kumar 
Published: February 2024

Background: Kostha vaddhata (constipation) is one of the common problems of human beings on society which is mainly based on the state of Agni. Because the vikrita agni is responsible for creating different types of Ajirna which is the initial or earlier symptom of Grahani Dosha. The aim of the study was to explain the principle of application of Gavya–ghrita mixed with saindhav lavana to treat the Kostha vaddhata. Materials and Methods: Based on the signs and symptoms of Kostha vaddhata (constipation), Saindhava Lavana mixed with Ghrita described in Charaka Samhita was taken for clinical trial. Thirty number of patients, satisfying the inclusion criteria, were taken for the present study and all patients were divided into two equal groups, that is, Group A and Group B. The assessment was made before and after treatment. Results: The better result was obtained when Gavya Ghrita mixed with Saindhava Lavana. Discussion and Conclusion: Finally, it can be said that the formulation, that is, Gavya Ghrita mixed with Saindhava Lavana could be the best tool for the management of Kostha Vaddhata and it also justifies the Siddhanta of Maharshi Charaka. Hence, the research needs further studies with larger samples, and increased duration of medicine could be more informative.
Management of Indralupta (Alopecia areata) by Jaluka Avacharana and Shamana Aoushadhi: A Case Report
Authors: Rani Pooja , Rathi Mini , Chandrakar Vinita , Tanwar Vipin 
Published: February 2024

Background: Alopecia areata is an autoimmune disorder that can lead to unpredictable hair loss. Alopecia areata is a common autoimmune disorder that often results in unpredictable hair loss. In most cases, hair falls out in small patches around the size of a quarter. There may be only a few patches, but alopecia areata can affect wider areas of the scalp. In Ayurveda texts, a similar condition is mentioned in Kshudrarogas known as Indralupta. Aims: This study sets out to evaluate the effectiveness of Shamana Aoushadhi and Jalaukavacharana in curing Alopecia areata. Materials and Methods: It is a single-case study of a 24-year-old female patient with a complaint of asymptomatic loss of hair at a single site over the scalp with itching and dandruff for 1.5 years. This case of Alopecia areata (Indralupta) was successfully treated with seven sittings of Jalaukavacharana (leech therapy) and Ayurveda medication. Result: The patch was immensely filled with lustrous black hairs at the end of the follow-up period. Conclusion: Thus, it can be said that Jaloukavacharana and Shamana Aushadh, two Ayurvedic treatments, offer a favorable outcome for Indralupta patients.
Management of Renal Calculus through Ayurveda: A Case Report
Authors: Dev Kapil , Gill Gurpreet Kaur , Yadav C R , Singh Bhanu Pratap 
Published: February 2024

Introduction: Renal calculus is one of the most common and prevalent diseases of urinary system. It affects all countries of the world with an approximate global lifetime prevalence of 15–20%. The etiology of renal calculus is multifactorial. It bears closest resemblance to Vrikkashmari in Ayurveda. Existing non-invasive treatment modalities available in contemporary medical science have limitations in terms of efficacy and cause various adverse effects. Hence, this study is aimed to explore effective alternate in the traditional systems for satisfactory management of this disease condition. Materials and Methods: A 50-year-old female patient visited the OPD of an Ayurveda hospital with complaints of pain in the right and left flanks radiating to the lower back, burning micturition, and nausea and vomiting for 20 days. The USG report revealed about two renal calculi measuring 6 mm and 8 mm in the right and left kidneys, respectively. Ayurvedic medicines such as Shweta Parpati, Hazrulyahud Bhasma, Gokshuradi Guggulu, Chandraprabha Vati, and Varunadi Kwatha were given to the patient for 1 month. Results: A significant remission was reported in clinical symptoms as well as in imaging findings after the use of this Ayurvedic treatment protocol.
Dispersal and persistence of cup plant seeds (Silphium perfoliatum): do they contribute to potential invasiveness?
Authors: Ende L. Marie , Hummel Lukas , Lauerer Marianne 
Published: February 2024

Background and aims – The cup plant (Silphium perfoliatum) is being grown in Germany as a promising new bioenergy crop with an increasing area under cultivation in the last years. Its alien status, its high productivity, and high reproductive potential could carry the risk of this species becoming invasive. The present study investigates the dispersal and persistence of cup plant seeds, to contribute to the assessment of its invasive potential.
Material and methods – For this purpose, four experimental studies were conducted in Germany, Central Europe: wind dispersal distance was measured in a field experiment for wind speeds up to 7 m.s-1. The seeds were offered to rodents in different habitats near to a cup plant field. We observed seed persistence and germination over 4 weeks storing in water and over 4 years storing in different soil depths.
Key results – Cup plant seeds are dispersed by wind only over a few meters. In the forest, rodents removed 100% of the offered seeds, in open habitats none. Independent of the duration of storage in water, germination rate of the cup plant seeds was constantly high. Most of the seeds already germinated in water in the first two weeks. Stored on the soil surface and at 10 cm soil depth, the seeds germinated already in the first two years. Stored at 30 cm depth, one third of the seeds retained their germination ability over four years.
Conclusion – Wind serves as short-distance dispersal vector for cup plant seeds. Rodents remove the seeds, but it is unknown whether they disperse them or just eat them. Water could disperse the seeds, which retain their germination ability, over long distances. The cup plant could therefore spread and possibly become invasive in Central Europe, and therefore measures are suggested to prevent its dispersal and spontaneous settlement.
lncRNA GAPLINC regulates vascular endothelial cell apoptosis in atherosclerosis
Authors: Pan Jun , Wang Bing , Pu Xibin , Qiu Chenyang , Li Donglin , Wu Ziheng , Zhang Hongkun , He Yangyan 
Published: February 2024

IntroductionIn this study, we investigated the role of the long non-coding RNA GAPLINC in atherosclerosis under oxidized low-density lipoprotein (ox-LDL) treatment.Material and methodsWe utilized ox-LDL exposed human aortic endothelial cells as an in-vitro model. The expression level of GAPLINC was quantified by qPCR in different times and concentrations of ox-LDL treatment conditions. Cell apoptosis rate and cell cycle profiles were assessed by flow cytometry and TUNEL assay. The target association was confirmed using a luciferase reporter assay and Western blot.ResultsWe found that GAPLINC expression was induced by ox-LDL treatment, but cell proliferation ability was significantly inhibited. We further confirmed that overexpressing of lncRNA GAPLINC in ox-LDL-exposed HAECs decreased cell proliferation by increasing cell apoptosis and arresting cell cycle in G2/M and S phase. Importantly, the detailed mechanistic analysis elucidated that LncRNA GAPLINC acts as a decoy to sequester miR-183-5p to prevent it from binding to target PDCD4. MiR-183-5p targets GAPLINC, and PDCD4 is a downstream target of miR-183-5p, and the cellular effects of this direct interaction were confirmed by a rescue assay experiment.ConclusionsThe present study demonstrates that upregulation of lncRNA GAPLINC represses the binding of miR-183-5p to the PDCD4 promoter region and then promotes PDCD4 expression, thereby inducing cell apoptosis and suppressing endothelial cell proliferation.
Global burden and epidemic trends of gout attributable to high body mass index from 1990 to 2019
Authors: Jin Zhaokai , Wang Zhengming , Wang Rui , Xiang Sicheng , Zhang Weiqing , Tang Yi , Tong Peijian , Gu Yong , Lv Shuaijie 
Published: February 2024

IntroductionGout is an inflammatory and metabolic disease characterized by arthritis and elevation of the serum uric acid (SUA) level. More and more studies have shown that high body mass index (BMI) has become one of the most important risk factors for gout.Material and MethodsWe used the data of gout burden attributed to high body mass index (BMI) from global burden of disease (GBD) study 2019 to provide insights for reducing the global burden of gout.ResultsFrom 1990 to 2019, the prevalence and DALYs of gout caused by high BMI worldwide has been increasing. The burden of gout caused by high BMI is heavier in the elderly male group and regions with high SDI worldwide.ConclusionsOur findings provide evidence for the burden of gout caused by high BMI. Developing a weight management plan and lifestyle habits for groups severely affected by gout will effectively reduce the global disease and economic burden.
Obesity and lung cancer – is programmed death ligand-1 (PD-1L) expression a connection?
Authors: Gałązka Jakub Krzysztof , Czeczelewski Marcin , Kucharczyk Tomasz , Szklener Katarzyna , Mańdziuk Sławomir 
Published: February 2024

IntroductionIn this retrospective study, the authors evaluated whether obesity-induced immunomodulation impacts the expression of programmed death ligand-1 (PD-1L) in lung cancer cells.MethodsA retrospective cross-sectional study was performed. The study included 67 patients. The data did not have a normal distribution.ResultsFor women, using ANOVA test (p = 0.050) with post-hoc analysis, a statistically significant difference in expression was found between women with overweight and women with normal weight (p = 0.040).ConclusionsApart from the above, the authors did not find any statistically significant correlation between PD-1L expression on lung cancer cells and body mass index, either in the whole group or in histological subgroups.
Level of basic hope and symptoms of anxiety and depression in women after miscarriage
Authors: Białek Katarzyna , Sadowski Marcin , Adamczyk-Gruszka Olga , Młodawski Jakub , Świercz Grzegorz 
Published: February 2024

IntroductionThe study aimed to determine the level of basic hope and symptoms of anxiety and depression in women after miscarriage.MethodsTo evaluate the symptoms of anxiety and depression, and basic hope, the standardized questionnaires the Hospital Anxiety and Depression Scale (HADS) and the Basic Hope Inventory (BHI-12), respectively, were used. Patients hospitalized at the Department of Obstetrics and Gynaecology of the Provincial Combined Hospital in Kielce due to miscarriage in the period from September 2019 to August 2021 were included in the study.ResultsThe sense of basic hope increased after 3 months (p < 0.001). The intensity of symptoms of anxiety and depression decreased (p < 0.001). The BHI-12 correlated significantly and negatively with the level of anxiety (r = –0.438, p < 0.001) and depression symptoms (r = –0.456, p < 0.001) during and after hospitalization (anxiety r = –0.649, p < 0.001; depression r = –0.643, p < 0.001).ConclusionsIt was found that the level of hope significantly increased after 3 months compared to this level during hospitalization. Hope was associated with lower levels of anxiety and depression symptoms.
A simple program to improve the appropriateness of red blood cell transfusions in non-bleeding hospital patients: a before-and-after study
Authors: Herzyk Jan , Wilczek Dawid , Kopczyńska Renata , Czempik Piotr F. 
Published: February 2024

IntroductionTransfusion of red blood cells (RBCs) is not devoid of risks; nor is anemia. The aim of the study was to assess the usefulness of a program designed to improve the appropriateness of RBC transfusions in hospital patients.MethodsWe retrospectively analyzed time periods before and after program implementation.
Results: Before program implementation 415 out of 23492 (1.8%) patients received at least 1 RBC, whereas after implementation 162 out of 25062 (0.6%) did so. The percentage of appropriate RBC transfusions increased from 23.6 to 37.1%.ResultsBefore program implementation 415 out of 23492 (1.8%) patients received at least 1 RBC, whereas after implementation 162 out of 25062 (0.6%) did so. The percentage of appropriate RBC transfusions increased from 23.6 to 37.1%.ConclusionsA simple program may lead to a 3-fold decrease in transfusion rate and a significant increase in the percentage of appropriate RBC transfusions.
ĐÁNH GIÁ KẾT QUẢ PHẪU THUẬT U SỌ HẦU QUA ĐƯỜNG MỔ THÓP BÊN TRƯỚC
Authors: Lê Tường Kha , Nguyễn Kim Chung , Trần Minh Huy , Võ Thành Toàn , Lê Bá Tùng 
Published: February 2024

Mục tiêu: Đánh giá kết quả phẫu thuật u sọ hầu qua đường mổ thóp bên trước. Đối tượng và phương pháp nghiên cứu: Nghiên cứu hồi cứu mô tả hàng loạt ca các BN được chẩn đoán là u sọ hầu, được điều trị tại khoa Ngoại thần kinh bệnh viện Chợ Rẫy từ 01/2019 đến 06/2023, được phẫu thuật bằng đường mở sọ thóp bên trước và chúng tôi thu thập được 35 bệnh nhân thỏa mãn các điều kiện đã nêu. Kết quả: Trong 35 ca u sọ hầu được phẫu thuật qua đường mổ thóp bên trước, có 25,8% ca lấy toàn bộ u, 51,4% ca lấy ≥ 90% u. Chủ yếu tính chất u thường gặp là dạng hỗn hợp vừa có nang, vừa có mô đặc và kèm theo vôi hóa (80%). Phần lớn các ca sau phẫu thuật đều tỉnh táo GCS 14-15 điểm (74,3%). Biến chứng sau mổ có 6,4% ca động kinh, 2,9% ca yếu chi. Có 68,6% ca sau phẫu thuật ngày đầu có đái tháo nhạt. Trong đó ghi nhận có 35,3% là đái tháo nhạt vĩnh viễn, 29,4% đái tháo nhạt thoáng qua và 11,8% đái tháo nhạt ba pha. Về giải phẫu bệnh học, ghi nhận có 62,8% ca u sọ hầu dạng men bào, 34,3% ca u sọ hầu dạng nhú gai và 2,9% ca không phân loại được u. Trong 35 bệnh nhân u sọ hầu được phẫu thuật và điều trị, có 54,3% ca xuất viện với GOS5, 37,1% ca GOS4, 5,7% ca GOS2. Tỉ lệ tử vong sau điều trị là 8,6%. Tỉ lệ tái phát trong khi theo dõi và điều trị là 18%. Kết luận: Phẫu thuật u sọ hầu bằng đường mổ thóp bên trước không những có hiệu quả trong việc điều trị ngoại khoa u sọ hầu, mà còn góp phần đem lại tính thẩm mỹ và ít xâm lấn trong các phẫu thuật sọ não.
PHÂN TÍCH ẢNH HƯỞNG CỦA THỨC ĂN GIÀU CHẤT BÉO TỪ MỠ LỢN ĐẾN CHỈ SỐ ĐƯỜNG HUYẾT CỦA CHUỘT THÍ NGHIỆM
Authors: Chu Đình Thiện , Vũ Thị Huệ , Hoàng Đức Anh , Dương Thị Anh Đào 
Published: February 2024

Mục tiêu: Nghiên cứu được thực hiện nhằm phân tích ảnh hưởng của thức ăn giàu chất béo từ mỡ lợn đến chỉ số đường huyết của chuột thí nghiệm. Phương pháp: Chuột đực 8 tuần tuổi được chia thành 02 lô và tiến hành can thiệp dinh dưỡng trong 66 ngày. Một lô ăn giàu chất béo từ mỡ lợn và lô đối chứng ăn thức ăn bình thường. Chuột được theo dõi cân nặng thường xuyên 2 ngày/lần và kiểm tra đường huyết tại thời điểm kết thúc thí nghiệm bằng phản ứng dung nạp glucose (GTT) và insulin (ITT). Kết quả: Cân nặng của lô chuột ăn giàu chất béo từ mỡ lợn tăng đáng kể so với lô đối chứng với p<0.001. Chỉ số đường huyết của lô chuột ăn thức ăn giàu chất béo cao hơn so với lô đối chứng, tuy nhiên sự khác biệt không có ý nghĩa thông kê. Lô được ăn thức ăn giàu chất béo từ mỡ lợn đã gây ra rối loạn dung nạp glucose, khả năng dung nạp đường huyết của chuột đã bị suy giảm so với lô đối chứng. Mặc dù cơ thể chuột ăn nhiều mỡ lợn có thể bắt đầu rối loạn khả năng dung nạp đường huyết nhưng khả năng dung nạp insuline vẫn ổn định. Kết luận: Kết quả là cơ sở để tiến hành các nghiên cứu trong tương lại về việc đánh giá sự tác động của ăn giàu chất béo từ mỡ lợn đến quá trình hình thành và tiến triển của các bệnh rối loạn chuyển hóa như thừa cân, béo phì và tiểu đường type 2 do khẩu phần ăn giàu chất béo có nguồn gốc từ động vật gây ra.
Desarrollo económico territorial e inteligencia artificial (IA)
Authors: Villatoro Hernández Fernando 
Published: February 2024

En las últimas décadas, en América Latina han surgido diversas iniciativas de Desarrollo Económico Territorial (DET), impulsadas a partir de enfoques de instituciones supranacionales y autores que consideran el DET como un proceso de crecimiento multidimensional y cambio estructural en un territorio. Esto ha establecido un marco epistemológico para el desarrollo territorial endógeno y sistémico, que actualmente provee una valiosa herramienta para interpretar la realidad. Sin embargo, el futuro plantea nuevos desafíos para el DET. En este artículo, a manera de ensayo, se realizará una revisión bibliográfica que tienen por objetivo plantear una reflexión que evidencie la importancia y pertinencia de los algoritmos y de los Sistemas de Inteligencia Artificial en la construcción epistemológica del Desarrollo Económico Territorial (DET) actual.
ECA Estudios Centroamericanos, Vol. 78, No. 773, 2023: 99-114.