bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infecção da corrente sanguínea relacionada ao cateter de hemodiálise
Authors: Brito Francisca Iris Araújo de , Nascimento Maria Eduarda Silva do , Oliveira Daniele Soares de , Ribeiro Ana Gedália Dias , Lino Cristiane Ribeiro de Melo , Flor Joana Darc de Araújo , Souza Mariana da Silva , Pennafort Viviane Peixoto dos Santos , Nunes Vilani Medeiros de Araújo , Mendonça Ana Elza Oliveira de 
Published: January 2024

Objetivo: Conhecer a produção científica acerca das infecções da corrente sanguínea associadas ao cateter venoso central em indivíduos em tratamento de hemodiálise. Métodos: Trata-se de uma revisão integrativa, realizada em março de 2023, desenvolvida a partir de estudos disponíveis no formato digital, publicados em periódicos indexados às fontes de dados nacionais e internacionais na Literatura Latino-Americana e do Caribe em Ciências da Saúde, National Library of Medicine, SciVerse Scopus, Scientific Electronic Library Online e Wiley Online Library. Resultados: Identificou-se 13.299 artigos, após a implementação dos critérios de inclusão foram selecionados oito estudos como amostra final. A maioria das publicações eram internacionais e se concentraram no ano de 2022, evidenciou-se números preocupantes acerca de infecções relacionadas ao cateter para hemodiálise por microrganismos gram-positivos, estando associadas às internações hospitalares e mortalidade populacional. Considerações finais: O estadiamento infeccioso encontra-se associado à presença de fatores de risco que permeiam desde aspectos individuais, aspectos relacionados aos microrganismos e à própria terapia hemodialítica. Os cuidados identificados na literatura irão subsidiar a elaboração de critérios de qualidade para o monitoramento dos pacientes em uso de cateter, com vistas à redução de infecções e aprimoramento de processos para o controle destas.
Blood and Bleeding Management in Developing Economies: Perceptions, Preparedness, and the Evolving Practices
Authors: Mishra Anurag Kumar , Agarwal Atul Kumar , Gandhi Ajay 
Published: January 2024

Objectives:
The growing concerns around the judicious use of blood components have paved the way for the dissemination of awareness around the best practices related to the use of this precious resource. With the World Health Organization issuing a policy brief on the urgent implementation of Patient Blood Management (PBM), there has been an accelerated impetus within the healthcare ecosystem to imbibe and implement the principles and practices of PBM. This research work aims to understand the current level of understanding, adequacy, and appropriateness of practices and readiness toward the universal and standardized implementation of PBM.

Approach:
This article summarizes the findings of an online survey. The survey consisted of a Google Form questionnaire with responses in multiple-choice, open and closed ends, as well as short notes. The survey responses were analyzed and summed up graphically. The survey established that there is still a huge gap in the “multispecialty approach” to setting up of the safe tolerance limits to anemia, optimal cutoffs, and thresholds for transfusion and shifting focus from “blood product” safety to “patient” safety.

Conclusion:
A lot of guidance- and evidence-based recommendations on transfusion practices are available in developed economies; the developing world still continues to weigh the advantages against the availability of and access to resources needed for implementation. Within these economies, and among different strata of healthcare infrastructure, there is still a significant difference in the perceptions and practices around blood transfusion and bleeding management.
Pengembangan Media Pembelajaran Interaktif Edpuzzle dalam Pembelajaran Sejarah
Authors: Purmintasari Yulita Dewi , Lesmana Chandra 
Published: January 2024

Learning history is one of the most difficult lessons because of the distance in space and time, so it is necessary to present interactive learning media that make historical values more understandable. The development of Edpuzle interactive video learning media in history learning aims to develop learning media and to determine the effectiveness of the product developed. The research process applies the 4D development research method with the stages of Define, Design, Develop and Deseminate. The research instruments are in the form of expert validation sheets, lift sheets and test questions. The results of the media validation show "very good" worthy of being used as a learning medium with an average score of 4.35. Based on table 2, it shows that the results of the validation of material experts average score of 4.33 in the "very good" category. The results of the one to one evaluation show that the average total score is 3.98 in the "good" category. And the results of the small group evaluation show that the total average score is 4.58 in the "very good" category. the results of the effectiveness test using Mann Whitney U on SPSS, obtained the results of a sig (2-tailed) value of 0.011 <0.05 which means Ho is rejected while Ha is accepted which means the use of interactive media has an effect on learning students become more interested and able to think interactive learning media and not boring.Pembelajaran sejarah merupakan salah satu pembelajaran yang sulit karena jauhnya ruang dan waktu, sehingga perlu menghadirkan media pembelajaran interaktif yang membuat lebih memahami nilai-nilai sejarah. Pengembangan media pembelajaran video interaktif edpuzle pada pembelajaran sejarah bertujuan untuk mengembangkan media pembelajaran dan mengetahui efektivitas produk hasil pengembangan. Penelitian menerapkan metode penelitian pengembangan 4D dengan tahapan Define, Design, Develop dan Deseminate. Instrumen penelitian berupa lembar validasi ahli, lembar angkat dan soal tes. Hasil validasi media menunjukkan “sangat baik” layak digunakan sebagai media pembelajaran dengan skor rata-rata 4,35. Berdasarkan tabel 2 menunjukkan bahwa hasil validasi ahli materi skor rata -rata 4,33 dengan kategori “sangat baik”. Hasil evaluasi one to one menunjukkan bahwa total skor rata -rata 3,98 dengan kategori “baik”. Dan hasil evaluasi small group menunjukkan bahwa total skor rata -rata 4.58 dengan kategori “sangat baik”. hasil uji efektivitas menggunakan Mann Whitney U pada SPSS, didapatkan hasil nilai sig (2-tailed) sejumlah 0,011 < 0,05 yang berarti Ho ditolak sedangkan Ha diterima yang berarti penggunaan media interaktif berpengaruh dalam pembelajaran. siswa menjadi lebih tertarik dan mampu berfikir dengan media pembelajaran yang interaktif dan tidak membosankan.
Perbandingan Penerapan Algoritma Decision Tree C.45 dan Naïve Bayes Dalam Analisa Kelulusan Siswa pada SMK Swadhipa 2 Natar Kabupaten Lampung Selatan
Authors: Susanti Yus , Choyyin Muhammad Gus , Priyatna Aziz , Lestari Sri 
Published: January 2024

Salah satu penerapan data mining pada bidang pendidikan seperti untuk memprediksi kelulusan siswa sekolah. Prediksi kelulusan siswa ini menggunakan data yang berasal dari transkip nilai akhir dari masing-masing siswa, adapun atribut yang digunakan yakni nilai rata-rata pelajaran Bahasa Indonesia, Bahasa Inggris, dan Matematika mulai dari semester 1 hingga semester 5 serta riwayat SP yang pernah didapat selama siswa tersebut sekolah. Pada penelitian ini menggunakan dua metode data mining, yaitu algoritma C4.5 dan Naïve bayes. Penggunaan dua metode pada penelitian Akurasi: Decision Tree C4.5 memiliki akurasi sebesar 80%, sedangkan Naïve Bayes memiliki akurasi sebesar 75%. Hal ini menunjukkan bahwa Decision Tree C4.5 lebih akurat dalam memprediksi kelulusan siswa dibandingkan dengan Naïve Bayes.Presisi: Decision Tree C4.5 memiliki presisi sebesar 82%, sedangkan Naïve Bayes memiliki presisi sebesar 78%. Decision Tree C4.5 memiliki tingkat presisi yang sedikit lebih tinggi dibandingkan dengan Naïve Bayes.Recall: Decision Tree C4.5 memiliki recall sebesar 75%, sedangkan Naïve Bayes memiliki recall sebesar 80%. Naïve Bayes memiliki tingkat recall yang sedikit lebih tinggi dibandingkan dengan Decision Tree C4.5. F1-score: Decision Tree C4.5 memiliki F1 score sebesar 78%, sedangkan Naïve Bayes memiliki F1-score sebesar 76%. F1-score Decision Tree C4.5 sedikit lebih tinggi dibandingkan dengan Naïve Bayes. Kata Kunci: Data mining, Clacification, C4.5 Algoritma, Naive Bayes
Sorotan Fundamentalisme Islam Terhadap Kepala Sekolah Perempuan
Authors: Susilawati Susilawati , Danil Ilham 
Published: January 2024

<p align="left"><strong>Abstract <em></em></strong></p><p>The creation of Siti Hawa from the ribs of the prophet Adam is a sign that women are physically weaker than men. Therefore also the background so that they often get unfair treatment or discrimination. But over time, the signal has faded, especially in Indonesia. This fact is inseparable from the services of a female emancipation warrior, RA Kartini. Today many women are as successful as men. No longer can the number of those who hold the reins of leadership be counted, one of them being the headmaster in various educational institutions, ranging from the lowest level of education to tertiary education. Whereas leadership positions in the education sector are very urgent and determine whether or not the vision, mission and goals of education are achieved or not. An in-depth study of opinions which states that "actually women have the same potential as those of men". No matter how great a woman is, she can't be released as a housewife.</p><p><strong> </strong></p><p><strong><em>Abstrak</em></strong></p><p><em>Terciptanya Siti Hawa dari tulang rusuk nabi Adam merupakan satu isyarat bahwa kaum perempuan itu lebih lemah fisiknya dibanding kaum pria. Oleh karena itu pulalah yang menjadi latar sehingga mereka sering mendapat perlakuan tidak adil alias diskriminasi. Namun seiring berjalannya waktu, isyarat itu telah pudar, khususnya di Indonesia. Kenyataan ini tak lepas dari jasa seorang pejuang emansipasi wanita, RA Kartini. Hari ini banyak sudah kaum perempuan yang berhasil seperti kaum laki-laki. Tak lagi dapat dihitung jumlah mereka yang memegang tampuk-tampuk kepemimpinan, salah satunya menjadi kepala sekolah di berbagai lembaga pendidikan, mulai dari tingkat pendidikan terendah sampai perguruan tinggi. Padahal jabatan kepemimpinan di sektor pendidikan sangat urgen dan menentukan tercapai atau tidaknya visi, misi dan sasaran pendidikan. Perlu kajian mendalam tentang pendapat yang menyatakan bahwa “sebenarnya perempuan memiliki potensi yang sama sebagaimana yang dimiliki oleh laki-laki”. Karena sehebat apapun seorang perempuan, titel sebagai ibu rumahtangga tak dapat ia lepaskan.</em></p>
In-store remote collaborative shopping using mobile technology: A qualitative study with premium beef consumers
Authors: Chowdhury Shahan Ahmad 
Published: January 2024

<p> </p>
<p>Collaborative shopping aims to improve the quality of purchase decisions and fulfills a social need for shoppers. Food shopping provides a collaborative shopping context, however, there is a lack of research into collaborative food shopping. This research explored premium beef consumers’ in-store remote collaborative shopping and use of mobile technology through a qualitative study. Six semi-structured interviews were conducted with premium beef consumers to understand their remote collaborative shopping. Data were analyzed using thematic analysis. The study revealed that the main trigger for remote collaboration was to confirm the purchase with a remote partner. The results also identified that current mobile technology is sufficient for remote collaboration. However, participants were interested in using dedicated technological tools to support their remote collaborative shopping. This paper presents an understanding of remote collaborative shopping and what factors need to be consider before designing remote collaborative shopping tools and provides direction for future research. </p>
Pengaruh Latihan Bola Gantung terhadap Kemampuan Service Permainan Sepak Takraw pada Atlet Sepak Takraw PPLP Riau
Authors: Raja Febri Irawady  , Zainur  , Syahriadi  
Published: January 2024

Masalah dalam penelitian ini adalah bahwa atlet tersebut masi kurang, Servis sering gagal mendapatkan point, karena laju bola kurang keras terlalu mudah di terima lawan, bola sering menyangkut di net, dan saat melakukan servis kurang tepat sasaran atau bola keluar atlet PPLP Riau. Tujuan peneliti ini adalah untuk mengetahui Pengaruh metode latihan bola gantung terhadap kemampuan service permainan sepak takraw pada atlet sepak takraw PPLP Riau. Metode penelitian ini adalah penelitian eksperimen lapangan, rancangan penelitian yang digunakan adalah pretest- posttestest only one grup design, Populasi dalam penelitian ini ada sebanyak 8 peserta PPLP Sepak Takraw Riau yang masih aktif . Instrumen yang digunakan dalam penelitian ini adalah tes service sepaktakraw. Teknik analisis data menggunakan uji normalitas dan uji t, untuk mengetahui pengaruh sebelum dan sesudah latihan yang diberikan. Berdasarkan hasil analisis uji hipotesis diperoleh harga thitung (6.60) > ttabel (1.895) pada taraf signifikansi α = 0,05 pada jumlah sampel berjumlah 8. Jadi dapat disimpulkan bahwa Ho ditolak dan Ha diterima. Dengan demikian dapat disimpulkan bahwa latihan service bola gantung berpengaruh terhadap kemampuan service permainan sepaktakraw pada atlet sepaktakraw PPLP Riau.
Interventions for Persons with Young-Onset Dementia and Their Families: A Scoping Review
Authors: Cui Xiaoyan , Wang Junqiao , Wu Bei , Zhao Qianhua , Tang Xueting , Wang Jing 
Published: January 2024

Background: Dementia occurring before age 65 is known as young-onset dementia (YOD), with Alzheimer’s disease being the most common type. YOD poses unique challenges for persons and families, impacting their working-age years and family responsibilities. Person-centered interventions and services are essential to improve their quality of life and social engagement. Objective: This study aims to synthesize non-pharmacological interventions for persons with YOD and their families to inform future targeted interventions. Methods: We conducted a systematic literature search across four databases: PubMed, PsycINFO, Scopus, and CINAHL. The included articles were carefully screened, categorized, and synthesized by following Arksey and O’Malley’s five stages framework. Results: We included 20 studies reported in 24 papers, with 11 studies (14 papers) on persons with YOD and nine studies (10 papers) on families. Quantitative intervention results vary, but qualitative interviews show positive feedback. Stakeholders provided positive evaluations, stating these interventions provided a sense of normalcy, facilitated communication among families, enhanced the independence of persons with YOD, and improved the families’ caregiving self-efficacy, thereby reducing care burden and psychological distress. The heterogeneity among the studies posed integration challenges. Conclusions: Interventions for YOD can improve the quality of life for both persons with YOD and their families. More extensive intervention studies are urgently needed, especially in developing countries, with a focus on family-centered and life course perspectives. In future intervention research design, a more extensive incorporation of stakeholder involvement is essential for successful implementation. Moreover, the integration of new technologies shows promise as a potential avenue for intervention advancement.
As repercussões do cuidar: Saúde mental de cuidadores familiares de pacientes oncológicos
Authors: Garcia falavinha Samantha , Beatriz Sehnem Scheila 
Published: January 2024

Introdução: A presente pesquisa versa sobre cuidadores de pacientes oncológicos e as implicações de suas funções sobre sua saúde mental. Objetivo: Avaliar os níveis de saúde mental dos familiares cuidadores e suas implicações. Método: Trata-se de uma pesquisa de caráter quali quantitativo do tipo descritiva, realizada nas dependências do Hospital Universitário Santa Terezinha – HUST, de Joaçaba, SC, com 20 (vinte) participantes. Os recursos técnicos utilizados para de dados e informações foram um Questionário Semiestruturado de dados Sociodemográficos, Questionário de Saúde Geral de Goldberg e Inventários Beck (BHS, BAI, BDI). Resultados: Os resultados obtidos indicam presença de sintomas ansiosos, depressivos e de desesperança em todos os cuidadores familiares entrevistados. Conclusão: Em ampla análise, conclui-se estes não apresentarem, em sua maioria, níveis graves ou superiores à média geral indicada, assinalando a necessidade e importância de se desenvolver novos estudos acerca do tema e promover o estabelecimento de estratégias de prevenção e enfrentamento.
Short Studies: An Overview of Empowering Global Maritime Technology on Indonesia Seaweed Industries Innovations in 2045
Authors: Widodo Wibawanto Nugroho , Mangkurat Bayu , Rahmiati Filda , Nurwaesari Nana , Susanto AB , Susanto Agus Hery , Pangestuti Ratih , Puspita Maya 
Published: January 2024

<span lang="EN-ID">Republic of Indonesia as an archipelagic state actor within the international system plays its significant role to build, secure, and use its maritime domain in the most strategic sense to protect and advance its national interests within the cooperative, competitive, and conflictual setting at the world stage. In order to reach the 2045 vision, Indonesia as the world's maritime axis in Golden Indonesia 2045, the realization of this vision cannot be carried out without the help of technological advances. </span><span lang="EN-ID">Younger generation as human resources also plays an important role to support this mission. This research is using a qualitative study based on open sources data using the strategic policy as the unit of analysis. Furthermore, the study results show several strategic policies that were compiled based on the 9 main agendas from the Coordinating Ministry for Maritime Affairs and Investment of the Republic of Indonesia; linking to technology and innovation needed. The strategic policies using PEST analysis, empower Indonesian youth and seaweed cultivation towards 2045 were analysed in these studies. This research presents several recommendations that can be implemented in encouraging the interest of the younger generation as the main actors in realizing Indonesia's World Maritime Axis in 2045 through the latest technology </span>
Deep learning-based automated pipeline for blood vessel detection and distribution analysis in multiplexed prostate cancer images
Authors: Karageorgos Grigorios M. , Cho Sanghee , McDonough Elizabeth , Chadwick Chrystal , Ghose Soumya , Owens Jonathan , Jung Kyeong Joo , Machiraju Raghu , West Robert , Brooks James D. , Mallick Parag , Ginty Fiona 
Published: January 2024

Introduction: Prostate cancer is a highly heterogeneous disease, presenting varying levels of aggressiveness and response to treatment. Angiogenesis is one of the hallmarks of cancer, providing oxygen and nutrient supply to tumors. Micro vessel density has previously been correlated with higher Gleason score and poor prognosis. Manual segmentation of blood vessels (BVs) In microscopy images is challenging, time consuming and may be prone to inter-rater variabilities. In this study, an automated pipeline is presented for BV detection and distribution analysis in multiplexed prostate cancer images.Methods: A deep learning model was trained to segment BVs by combining CD31, CD34 and collagen IV images. In addition, the trained model was used to analyze the size and distribution patterns of BVs in relation to disease progression in a cohort of prostate cancer patients (N = 215).Results: The model was capable of accurately detecting and segmenting BVs, as compared to ground truth annotations provided by two reviewers. The precision (P), recall (R) and dice similarity coefficient (DSC) were equal to 0.93 (SD 0.04), 0.97 (SD 0.02) and 0.71 (SD 0.07) with respect to reviewer 1, and 0.95 (SD 0.05), 0.94 (SD 0.07) and 0.70 (SD 0.08) with respect to reviewer 2, respectively. BV count was significantly associated with 5-year recurrence (adjusted p = 0.0042), while both count and area of blood vessel were significantly associated with Gleason grade (adjusted p = 0.032 and 0.003 respectively).Discussion: The proposed methodology is anticipated to streamline and standardize BV analysis, offering additional insights into the biology of prostate cancer, with broad applicability to other cancers.
Microfluidic-based human prostate-cancer-on-chip
Authors: Jiang Linan , Khawaja Hunain , Tahsin Shekha , Clarkson Tanjia A. , Miranti Cindy K. , Zohar Yitshak 
Published: January 2024

Lack of adequate models significantly hinders advances in prostate cancer treatment, where resistance to androgen-deprivation therapies and bone metastasis remain as major challenges. Current in vitro models fail to faithfully mimic the complex prostate physiology. In vivo animal models can shed light on the oncogenes involved in prostate cancer development and progression; however, the animal prostate gland is fundamentally different from that of human, and the underlying genetic mechanisms are different. To address this problem, we developed the first in vitro microfluidic human Prostate-Cancer-on-Chip (PCoC) model, where human prostate cancer and stromal fibroblast cells were co-cultivated in two channels separated by a porous membrane under culture medium flow. The established microenvironment enables soluble signaling factors secreted by each culture to locally diffuse through the membrane pores affecting the neighboring culture. We particularly explored the conversion of the stromal fibroblasts into cancer-associated fibroblasts (CAFs) due to the interaction between the 2 cell types. Immunofluorescence microscopy revealed that tumor cells induced CAF biomarkers, αSMA and COL1A1, in stromal fibroblasts. The stromal CAF conversion level was observed to increase along the flow direction in response to diffusion agents, consistent with simulations of solute concentration gradients. The tumor cells also downregulated androgen receptor (AR) expression in stromal fibroblasts, while an adequate level of stromal AR expression is maintained in normal prostate homeostasis. We further investigated tumor invasion into the stroma, an early step in the metastatic cascade, in devices featuring a serpentine channel with orthogonal channel segments overlaying a straight channel and separated by an 8 µm-pore membrane. Both tumor cells and stromal CAFs were observed to cross over into their neighboring channel, and the stroma’s role seemed to be proactive in promoting cell invasion. As control, normal epithelial cells neither induced CAF conversion nor promoted cell invasion. In summary, the developed PCoC model allows spatiotemporal analysis of the tumor-stroma dynamic interactions, due to bi-directional signaling and physical contact, recapitulating tissue-level multicellular responses associated with prostate cancer in vivo. Hence, it can serve as an in vitro model to dissect mechanisms in human prostate cancer development and seek advanced therapeutic strategies.