bluuebunny/crossref_metadata_2025_split huggingface dataset:
In the periphery of an indefinite pronoun. Forms and functions of conceptual agreement with jemand
Authors: Ellsäßer Sophie 
Published: September 2023

Abstract
In German, the social gender of the human referent matches the grammatical gender of the noun and pronoun in many cases. Nevertheless, those categories can also differ from each other. The indefinite pronoun jemand ‘someone’ prototypically exhibits masculine grammatical gender irrespective of its concrete referents. This paper addresses a special phenomenon that can occur with jemand, namely, the conceptual agreement of relative pronouns, i.e., the occurrence of feminine target forms that refer to the masculine indefinite pronoun jemand (Sie ist jemand, die gerne Kaffee trinkt ‘She is someone
m
, who
f
likes to drink coffee’). Based on two empirical analyses that examine the phenomenon from different methodological perspectives, this article will demonstrate that the marked phenomenon is comparatively rare, but does occur nevertheless. The phenomenon cannot be fully explained by the loss of the genericity of indefinite pronouns. In fact, either semantic or pragmatic explanations can be applied. This phenomenon can especially be observed in specific types of contexts (or constructions) that lack the prototypical feature of indefinite pronouns: indefinite reference. Jemand increasingly seems to be emerging in non-prototypical contexts for indefinite pronouns, which to some extent override the morphosyntactic features of the (relevant) part of speech. This occurrence is a semantic explanation for conceptual agreement forms. Pragmatic explanations for variation in agreement forms can be applied in prototypical contexts of indefinite pronouns, for example when an effort to use gender-sensitive language is made. Based on the phenomenon of conceptual agreement, this article thus explores the functions and properties in the periphery of indefinite pronouns as a part of speech.
Diz-me o que aprendes, dir-te-ei que professor podes ser... a formação dos professores de História em Portugal
Authors: Pereira Henriques Raquel , Pinto Ribeiro Cláudia 
Published: September 2023

Este artigo parte do pressuposto de que é possível conhecer a formação de professores de História a partir da análise do que aprendem e do modo como aprendem, na sua formação inicial, no âmbito do Mestrado em Ensino de História no 3.º Ciclo do Ensino Básico e no Ensino Secundário. Assim, a partir da análise dos programas das unidades curriculares da área da didática específica e dos documentos relativos ao processo de avaliação e acreditação dos ciclos de estudos, procurámos traçar perfis e desenhar percursos de formação para a docência em todos os estabelecimentos de ensino superior que asseguram a profissionalização em História.
A consulta de documentação diferenciada quanto à sua natureza permitiu a utilização de distintas metodologias. A análise dos programas das unidades curriculares recorreu à identificação de palavras-chave ou conceitos estruturantes que permitissem a definição de categorias que organizassem as principais conclusões. A leitura dos diversos relatórios que resultam do processo de avaliação e acreditação dos ciclos de estudos admitiu uma abordagem diferente: optámos por analisar o processo individual de cada estabelecimento de ensino, desde o “grau zero” até ao momento da segunda acreditação.
As principais conclusões apontam para a) a preocupação em formar professores de história flexíveis, capazes de se adaptarem às necessidades atuais e futuras, comprometidos com a construção do conhecimento e com a articulação da investigação com a prática; b) a necessidade de investimento, por parte das instituições universitárias, na contratação de pessoal docente especializado; c) a importância de se diluir a subjetividade que decorre da constituição de equipas diferentes na avaliação dos ciclos de estudos, através da discussão prévia dos contextos e das medidas a aplicar, antes da divulgação do relatório preliminar da Comissão de Avaliação Externa.
Contribution to Taxonomic Knowledge of Crepis dioritica (Asteraceae): A Threatened Endemic Species in Türkiye
Authors: İNCEER Hüseyin 
Published: September 2023

Aim of study: Crepis dioritica Schott & Kotschy ex Boiss. (=Crepis albiflora Babcock) is a threatened endemic species in Türkiye. The aim of this study is to contribute taxonomic knowledge of this species, and to reasses of its IUCN Red List category.
Area of study: Bolkar Mountains (Niğde) and Irano-Turanian region.
Material and methods: The comprehensive floristic studies in type locality of C. dioritica in Bolkar Mountains were carried out. Besides, the specimens previously collected from the type locality and Irano-Turanian region of the species were examined in detail.
Main results: The typification of the name Crepis dioritica erronously cited as holotype was corrected to lectotype herein. Besides, the IUCN category of the species was reassesed as VU (vulnerable), and its distribution pattern was given in detail for the first time.
Highlights: The data obtained from this study can be used for nomenclature and taxonomy of C. dioritica.
Intersectoral Flows in the Economies of the Visegrad Group Countries
Authors: Przybyliński Michał , Trębska Joanna 
Published: September 2023

We present a comparative study of flows between institutional sectors in the economies of Czechia, Hungary, Poland and Slovakia, with particular emphasis on the role of the foreign sector. The purpose of our study is to determine the strength and nature of inter‑sectoral ties in the analyzed countries and point out the similarities and differences between them. The research method is based on the sequence of all transactions included in the System of National Accounts (SNA): product transactions, primary income generation and allocation, income distribution, and financial instrument transactions. The study is distinguished by its consistency and balance within the SNA. The method used to transform data into a payer‑payee matrix guarantees the preservation of these properties. It creates a new perspective for assessing the sensitivity of economies to external processes.
It is the first such comprehensive comparative study, providing unambiguous and replicable results based on a standardized accounting system that operates in all European countries. The period covered by the study (2000–2020) allows us to draw interesting conclusions about the processes that took place during and after the accession to the European Union. The results indicate, inter alia, an increase in the involvement of the foreign sector, primarily in production processes (import, export) and investment. Particularly noteworthy is the high degree of financialization of the Hungarian economy.
ANALYSIS OF THE CLIMATIC DEFLATION INDICATOR DYNAMICS ON THE EXAMPLE OF ERZIN WEATHER STATION DATA
Authors: Kozlova Inga V. , Zenkova Zhanna N. , Kvasnikova Zoya N. 
Published: September 2023

Link for citation: Kozlova I.V., Zenkova Zh.N., Kvasnikova Z.N. Analysis of the climatic deflation indicator dynamics on the example of Erzin weather station data. Bulletin of the Tomsk Polytechnic University. Geo Аssets Engineering, 2023, vol. 334, no. 9, рр. 154-162. In Rus.
The relevance of the research is caused by the need to identify factors affecting the development of deflationary processes of arid geosystems of the Tuva Republic. This will allow us to propose further measures to reduce the degradation of agricultural land and minimize the development of land desertification. Objective: assessment of climatic conditions and identification of anthropogenic factors of the potential danger of deflation to monitor changes in vulnerable geosystems and natural and anthropogenic processes. Objects: a section of the north-eastern (Russian) part of the Ubsunur basin within the Erzinsky district of the Tuva Republic. Methods: statistical analysis, regressions, moving average, comparative geographical method, interpretation of satellite images. Results. The dynamics of the climatic index of deflation based on the data of the Erzin weather station for 1966–2020 is analyzed; graphs of changes in the temperature regime, the amount of precipitation, wind speed are plotted; a linear trend of the distribution of the average annual temperature is revealed; coefficients of the climatic index of deflation and aridity indices are determined, graphs of their dynamics for the period under study are plotted; a tendency to weaken deflation is revealed; the studied landscapes are subarid on average, and according to the index fluctuation – from weakly arid (0,6–0,8) to arid (0,3) and subarid (0,5 –0,6).
Combining SIRI and AFR to predict early serious complications and recurrent or metastases after respectable gastric cancer
Authors: Ren Jingyao , Wang Da , Zhu Lihui , Liu Shuo , Yu Miao , Cai Hui 
Published: September 2023

Abstract
Aims. The aim of this study was to assess the clinical importance and prognostic significance of systemic inflammatory response index (SIRI) and the albumin fibrinogen ratio (AFR) on early postoperative outcomes in patients undergoing radical gastric cancer surgery.
Methods. We conducted a retrospective analysis of the clinicopathological characteristics and relevant laboratory indices of 568 patients with gastric cancer. We examined the diagnostic ability of the combination of SIRI and AFR for early postoperative serious complications. We compared three groups of patients to evaluate the prognostic value of various preoperative SIRI-AFR scores for early postoperative recurrence or metastasis.
Results. The results demonstrated that the SIRI-AFR score was an independent risk factor for early postoperative recurrence or metastasis and had the highest diagnostic power for early serious complications in patients with gastric cancer.
Conclusion. Preoperative SIRI and AFR were significantly associated with early postoperative recurrence or metastasis and the occurrence of severe complications in patients with gastric cancer.
Harnessing the Potential of Exosomal miRNAs: A Breakthrough in Rheumatoid Arthritis Diagnosis and Monitoring
Authors: Gong Jianmin , Zhang Xiaoshan , Khan Adeel , Liang Jun , Xiong Tao , Yang Ping , Li Zhiyang 
Published: September 2023

Abstract
Background
Rheumatoid arthritis (RA) is an autoimmune disorder characterized by the inflammation-induced joint damage. Timely diagnosis and treatment are crucial to prevent lasting disability. Here, we aim to evaluate whether exosomal miRNAs could serve as promising biomarkers for expeditious RA diagnosis and effective therapy.
Methods
First, we performed small RNA sequencing to determine the miRNA profiles of serum exosomes within a screening cohort comprising 18 untreated active RA patients, along with 18 age and gender-matched healthy controls. Subsequently, the miRNA profiles were then validated in a training cohort consisting of 24 RA patients and 24 healthy controls, using RT-qPCR methodology. Finally, the selected exosomal miRNAs were subjected to validation in a larger cohort comprising 108 RA patients and 103 healthy controls. The diagnostic efficacy of the exosomal miRNAs was evaluated by receiver operating characteristic (ROC) curve analysis. The biological functions of the miRNAs were determined by gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) analyses.
Results
Our results first demonstrated a noteworthy upregulation of three specific miRNAs (miR-885-5p, miR-6894-3p, and miR-1268a) in the serum exosomes of patients of RA patients as compared with healthy controls. The combination of three miRNAs along with Anti-Cyclic Citrullinated Peptide Antibodies (ACPA) exhibited excellent diagnostic accuracy, yielding an area under the curve (AUC) of 0.963 (95% confidence interval = 0.941–0.984), a sensitivity of 87.96%, and a specificity of 93.20%. Notably, miR-885-5p exhibited remarkable discriminatory capacity by itself indistinguishing ACPA- negative RA patients from healthy controls, with an AUC of 0.993 (95% CI = 0.978-1), a sensitivity of 96.67%, and a specificity of 100%. Moreover, in the assessment of therapeutic effectiveness, the expression of miR-1268a displayed a significant reduction on the 29th day of MTX treatment in RA patients. This decline in expression paralleled the trends observed in TJC28 (28-joint tender count), SJC28 (28-joint swollen count), and DAS28-CRP (Disease Activity Score with 28-joint count using C-Reactive Protein), all of which are indicative of RA disease activity. Finally, predictive analysis indicated that all three exosomal miRNAs target pivotal signaling molecules involved in inflammatory pathways, thereby demonstrating effective modulation of the immune system.
Conclusions
In this study, we have successfully demonstrated the promising potential of serum exosomal miRNAs, particularly miR-885-5p, miR-6894-3p and miR-1268a, hold promising potential as biomarkers for the early diagnosis and prediction of RA for the first time. These findings highlight the importance of exosomal miRNAs in the realm of RA diagnosis and disease monitoring.
Medicinal Plant-based Biologically Active Substances and Extracts Inhibit Intestinal Autofluorescence Accumulation in Caenorhabditis elegans
Authors: Salimon Saoban Sunkanmi , Marusich Elena Ivanovna , Leonov Sergey Victorovich 
Published: September 2023

Abstract
Aging is a complex process related with the gradual diminution in cellular and physiological functions. The geroprotective effect of 10 biologically active substances (BAC – rutin, squalene, kaempferol, biohanin A, urosolic acid, chlorogenic acid, baicalin, mangiferin, quercetin and trans-cinnamic acid) and 5 crude extracts (Ginkgo biloba, Pulmonaria officinalis, Scutellaria baicalensis, Hedysarum neglectum and Panax ginseng) isolated from medicinal plants of Altai Region of Russia were evaluated for their influence on the accumulation of intestinal autofluorescence material (IAM) using Caenorhabditis elegans model. Gravid nematodes were synchronized, and then seeded in 96-well plates to develop to L4-stage. Each BAC in 200 µmol, 100 µmol, 50 µmol and 10 µmol concentrations and extracts with a tenth, hundredth and thousandth times-dilution were administered to each well in 6 replicates for each treatment group. On incubation days 1, 5, and 15, adult L4 nematodes underwent spectrofluorometric analysis to determine the effect of the BACs and extracts on IAM accumulation. It was found that quercetin, kaempferol, baicalin, mangiferin, Ginkgo biloba and Panax ginseng extracts exhibited the most profound inhibition of IAM accumulation compared to the control. Thus, they can be considered as important precursors or active ingredients for the pharmacosynthesis of geroprotective drugs in future research.
Efficacy of Supervised Self-Reduction vs Physician-Assisted Techniques for Anterior Shoulder Dislocations: A Systematic Review and Meta-Analysis
Authors: Hoveidaei Amir Human , Dankoub Mahdi , Nasab Mohammad Mehdi Mousavi , Ansari Amin Nakhostin , Pouramini Alireza , Eghdami Shayan , behbahani Fatemeh Mashaknejadian , Zangiabadian Moein , Forogh Bijan 
Published: September 2023

Abstract

background: The purpose of this study is to compare the efficacy of supervised self-reduction procedures versus physician-assisted techniques for treating anterior shoulder dislocations.
Method: We conducted a comprehensive search on PubMed, Scopus, Web of Science, and Cochrane up to March 22, 2023, using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) checklist. Relevant articles were reviewed, with a focus on studies comparing supervised self-reduction techniques to physician-assisted techniques in cases of anterior shoulder dislocation.
Results: The meta-analysis included four studies, with 283 patients in the physician-assisted group and 180 patients in the supervised self-reduction group participating. The success rate of supervised self-reduction techniques was significantly higher, with an odds ratio of 2.71 (95% CI 1.25-5.58, p-value = 0.01). Based on the Visual Analog Scale (VAS) score, the physician-assisted group reported significantly higher maximum pain, with a mean difference of 1.98 (95% CI 1.24-2.72, p-value < 0.01).
Conclusion: Supervised self-assisted techniques outperform in terms of success rate and reduction-related maximum pain. These techniques could be used as an effective first-line treatment for anterior shoulder dislocation, potentially reducing the need for analgesics and emergency room visits.
Pingchan Granule for objective and subjective insomnia in Parkinson's Disease: a multicentre, randomized, controlled, double-blind trial
Authors: Gu Sichun , Yin Ping , Cao Yang , Shi Rong , Li Qiang , Liu Jun , Wu Yun-Cheng , Zhang Yu , Wang Chang-De , Zhang Yun-Yun , Gu Min-Jue , Xu Li-Min , Gao Chen , Yuan Xiao-Lei , Wu You , Hu Yu-Qing , Yuan Canxing , Ye Qing 
Published: September 2023

Abstract
Background
Insomnia is a common and disabling nonmotor manifestation of Parkinson’s disease (PD). Drugs improving both parkinsonism and sleep would be of great benefit to patients with PD-related insomnia. Pingchan granule (PCG) is a traditional Chinese medicine for PD. The objective of this study was to test the efficacy and safety of PCG for insomnia associated with PD.
Methods
In this multicenter, randomized, double-blind, placebo-controlled trial, 100 participants were included and followed for 16 weeks (12-week treatment, 4-week follow-up after intervention), randomly assigned to receive PCG or placebo at a 1:1 ratio. The primary outcome was subjective PD-related insomnia evaluated by Parkinson’s disease sleep scale 2 (PDSS-2) score. Secondary outcomes included objective parameters of nighttime sleep by polysomnography and serum biomarker. As secondary outcomes, we also evaluated Insomnia Severity Index (ISI) score, Epworth Sleepiness Scale (ESS) score, rapid eye movement sleep behaviour disorder screening questionnaire (RBDSQ) score, Movement Disorder Society Unified Parkinson’s Rating Scale (MDS-UPDRS) I, II,and III scores, and Parkinson's disease questionnaire (PDQ-39) score. Assessments were conducted at baseline (T0), week 4 (T1), week 8 (T2), week 12 (T3) and week 16 (T4).
Results
The PCG group had significantly greater amelioration in PDSS-2 score than placebo group, as well as its domain scores of overall quality of night’s sleep, sleep onset and maintenance insomnia, nocturnal restlessness, nocturnal psychosis, nocturnal motor symptoms, and daytime dozing. PCG was associated with significant improvement in sleep efficiency, N3 sleep time, total sleep time, and interleukin (IL)-2/IL-4 ratio. Improvements of ISI, ESS, RBDSQ, MDS-UPDRS I, II, III, and PDQ-39 scores were also observed in PCG group compared with the placebo group
Conclusions
This trial provided class I evidence for the efficacy of PCG in treating insomnia in PD according to a wide range of subjective and objective sleep parameters with good tolerance, supporting that PCG might be a viable alternative in the management insomnia in PD.
Trial registration:
Chinese Clinical Trial Register, ChiCTR-INR-17011949 (11/07/2017).
The Effect of Formal Education on Ovarian Cancer and Clinical Trial Awareness Among Black and Latino US Women: The Promising Role of Annual Women’s Wellness Visits to Improve Health Literacy
Authors: Bakaj Amonda , Bakaj Angela , Lekaj Klaudi , Nwokeleme Treasure , Onigbinge Victoria , Gonzalez Indiara , Muyah Cynthia , Muyah Fanesse , Rocheburn Brianna , Ureta Elsie , Equils Ozlem 
Published: September 2023

Abstract

Background
Ovarian Cancer (OC) is ranked as one of the deadliest women’s cancers in the United States. Due to non-specific symptoms, it is often misdiagnosed and detected late. The mortality rate is higher and increasing among Black women. In addition, Black women have poor rates of participation in clinical trials.
Methods
We conducted a survey study among Black and Latino US women to understand the factors influencing their understanding of genetic risks of OC, clinical trial awareness and ability to access a clinical trial. MiOra health educators developed a SurveyMonkey-based survey and administered it to 226 women between the ages of 18 and 65 anonymously in their communities in three large US cities: Houston, TX, Atlanta, GA and Los Angeles, CA. The data was analyzed using two-sided Fisher’s exact and Chi-square tests.
Results
Out of the 226 respondents 63.4% were 30 years of age or younger and 22.9% had lower education (defined as having completed high school education or less. Out of 109 respondents, 93 (85.3%) self-identified as Black or Latino. Age did not influence self-reported awareness of genetic risk for OC, clinical trials or how to locate a clinical trial (Table 1). Lower education women were significantly less likely to report being knowledgeable about the genetic risk factors of OC, clinical trials or locating clinical trials (Table 1). Thirty out of 48 (62.5%) responding lower education women and 118 out of 173 (68.2%) responding higher education women reported to have an annual provider visit (p > 0.05). Self-reported awareness on how to locate a clinical trial was low in both the lower education (3 out of 48, 6.2%) and higher education groups (34 out of 171, 19.9%, p <0.05, Table 1).
Conclusions
These results suggest that the level of formal education influences the Black and Latino women’s awareness of OC genetic risk factors, OC clinical trials and clinical trial access. However, even among college educated Black and Latino women only a small portion reported to know how to locate a clinical trial. Interestingly, both high and lower education Black and Latino women reported to comply with annual provider visits. These visits may be an opportunity to close the health-literacy disparities in OC and clinical trials for Black and Latino women.
Clinical characteristics and managment of patient with portal hypertension at tertial level hospital in Tanzania
Authors: Itule Paul william , Mwanga Ally , Ramadhani Khamis , Byomuganyizi Moses , lutege william , Kagaruki Tryphone Buchard 
Published: September 2023

Abstract

Background
Portal hypertension is a common diagnosis in Sub-Saharan African countries, with the majority of patients presenting late. This study aimed to understand Clinical characteristics, etiology, the treatment offered in our setting, and factors associated with portal hypertension at a tertiary level hospital, in Tanzania.
Methodology:
A prospective cross-sectional observational single hospital-based study was conducted at MNH, from May 2021 to April 2022. A minimum of 152 subjects were required with an error of less than 5% and a study power of 80% at a 95% confidence interval. A structured questionnaire was used to collect data. Ethical clearance was obtained from the MUHAS/MNH IRB.
Results
A total of 154 eligible participants consented and participated in this study. The mean age of participants was 42 ± 15.8 years (range 2–87). The majority of the study participants were males 64.9% with a male to female (M: F) ratio of 1.8:1. Vomiting blood was the common symptom among the study participants 51.3%. Schistosomiasis 53.9% and viral infection 26.6% were the common etiologies followed by alcohol abuse 7.8%. Most were medically treated at 89.61% followed by radiological treatment at 8.44% while only 1.95% of patients received surgical treatment. There was a significant association between the grade of esophageal varices and bleeding consequences (p-value < 0.01).
Conclusion
The majority of patients were medically treated while patients who require surgical care are unable to assess it. We recommend the establishment of a transplant services program to counteract the unmet need and more retrospective research toward policy establishment.