bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence of deep vein thrombosis and symptomatic pulmonary embolism in Taiwanese patients with pelvic and/or acetabular fractures: a retrospective study
Authors: Hsiao Po-Meng , Liao Shu-Chen , Chen I.-Jung , Chou Ying-Chao , Hsu Yung-Heng , Wang Shu-Mei , Yu Yi-Hsun 
Published: September 2023

AbstractVenous thromboembolism (VTE) is common in patients with trauma, and thromboprophylaxis has been advocated. However, conflicting results regarding VTE rates in the Asian population following orthopaedic procedures have been presented. We aimed to investigate the VTE incidence in Taiwanese patients with pelvic and/or acetabular fractures and identify the associated risk factors. We included 402 patients who underwent surgery for pelvic and/or acetabular fractures. All patients received mechanical thromboprophylaxis with graduated compression stockings. Duplex scanning was performed postoperatively or during follow-up when signs or symptoms of deep vein thrombosis (DVT) developed. Variables with a significance level of ≤ 0.1 in the univariate analyses were introduced into the multivariate logistic regression analysis to identify DVT risk factors. The overall DVT and symptomatic pulmonary embolism (PE) rate was 3.48% (14/402 patients). Among patients with DVT, 46.1% were asymptomatic. Patients with VTE were significantly older than those without. Multivariate logistic regression analysis revealed that age was a VTE risk factor. The incidence of DVT and symptomatic PE in our cohort was low. Advanced age was a risk factor for VTE. These findings could help clinicians develop appropriate prevention and treatment strategies for VTE in Taiwanese patients with pelvic and/or acetabular fractures.
Exploring the role of miR-200 family in regulating CX3CR1 and CXCR1 in lung adenocarcinoma tumor microenvironment: implications for therapeutic intervention
Authors: Sharma Archana , Singh Prithvi , Jha Rishabh , Almatroodi Saleh A. , Alrumaihi Faris , Rahmani Arshad Husain , Alharbi Hajed Obaid , Dohare Ravins , Syed Mansoor Ali 
Published: September 2023

AbstractLung adenocarcinoma (LUAD) is the most common malignant subtype of lung cancer (LC). miR-200 family is one of the prime miR regulators of epithelial-mesenchymal transition (EMT) and worst overall survival (OS) in LC patients. The study aimed to identify and validate the key differentially expressed immune-related genes (DEIRGs) regulated by miR-200 family which may serve for therapeutic aspects in LUAD tumor microenvironment (TME) by affecting cancer progression, invasion, and metastasis. The study identified differentially expressed miRNAs (DEMs) in LUAD, consisting of hsa-miR-200a-3p and hsa-miR-141-5p, respectively. Two highest-degree subnetwork motifs identified from 3-node miRNA FFL were: (i) miR-200a-3p-CX3CR1-SPIB and (ii) miR-141-5p-CXCR1-TBX21. TIMER analysis showed that the expression levels of CX3CR1 and CXCR1 were significantly positively correlated with infiltrating levels of M0-M2 macrophages and natural killer T (NKT) cells. The OS of LUAD patients was significantly affected by lower expression levels of hsa-miR-200a-3p, CX3CR1 and SPIB. These DEIRGs were validated using the human protein atlas (HPA) web server. Further, we validated the regulatory role of hsa-miR-200a-3p in an in-vitro indirect co-culture model using conditioned media from M0, M1 and M2 polarized macrophages (THP-1) and LUAD cell lines (A549 and H1299 cells). The results pointed out the essential role of hsa-miR-200a-3p regulated CX3CL1 and CX3CR1 expression in progression of LC TME. Thus, the study augments a comprehensive understanding and new strategies for LUAD treatment where miR-200 family regulated immune-related genes, especially chemokine receptors, which regulate the metastasis and invasion of LUAD, leading to the worst associated OS.
Calcium wastes as an additive for a low calcium fly ash geopolymer
Authors: Chindaprasirt Prinya , Rattanasak Ubolluk 
Published: September 2023

AbstractA geopolymer is a low-carbon cement based on the utilization of waste ash in alkali-activated conditions. Coal fly ash is widely used as a source material for geopolymer synthesis since it contains a sufficient amount of reactive alumina and silica for geopolymerization. Geopolymer products are known to have beneficial fire resistance and mechanical properties. Class F or low-calcium fly ash (LCFA) is generally used as a primary aluminosilicate source; however, heat curing is required to complete the reaction and hardening process and achieve a strong composite. Furthermore, calcium additives are often required to improve the strength of LCFA geopolymers. This paper presents the potential of reusing calcium waste for this purpose. Three calcium wastes, namely calcium carbide residue (CCR), limestone waste, and waste cement (WC) slurry in powder form were used as additives and compared with the use of ordinary Portland cement (OPC). LCFA was replaced with the calcium additives at 20%. However, 20% CCR resulted in flash setting, hence 5% CCR was used instead. A durability test using 3% HCl solution was also performed. The results showed that the reactivity of calcium additives played an important role in strength development. In the calcium–aluminosilicate–alkali system, calcium silicate hydrate (CSH) and calcium aluminosilicate hydrate (CASH) were formed. The maximum strength of 21.9 MPa was obtained from the OPC/LCFA geopolymer, and 3% HCl solution had a deleterious effect on the strength. OPC and CCR were favorable reactive sources of calcium compounds to blend with LCFA. From the thermogravimetric results, lower thermal weight changes with higher strength gains were achieved. Low CaCO3decomposition at 750 °C according to the TGA curves indicated the more formation of thermally stable CSH and high compressive strength of Ca/LCFA geopolymers.
Dynamic full-field optical coherence tomography module adapted to commercial microscopes allows longitudinal in vitro cell culture study
Authors: Monfort Tual , Azzollini Salvatore , Brogard Jérémy , Clémençon Marilou , Slembrouck-Brec Amélie , Forster Valerie , Picaud Serge , Goureau Olivier , Reichman Sacha , Thouvenin Olivier , Grieve Kate 
Published: September 2023

AbstractDynamic full-field optical coherence tomography (D-FFOCT) has recently emerged as a label-free imaging tool, capable of resolving cell types and organelles within 3D live samples, whilst monitoring their activity at tens of milliseconds resolution. Here, a D-FFOCT module design is presented which can be coupled to a commercial microscope with a stage top incubator, allowing non-invasive label-free longitudinal imaging over periods of minutes to weeks on the same sample. Long term volumetric imaging on human induced pluripotent stem cell-derived retinal organoids is demonstrated, highlighting tissue and cell organization processes such as rosette formation and mitosis as well as cell shape and motility. Imaging on retinal explants highlights single 3D cone and rod structures. An optimal workflow for data acquisition, postprocessing and saving is demonstrated, resulting in a time gain factor of 10 compared to prior state of the art. Finally, a method to increase D-FFOCT signal-to-noise ratio is demonstrated, allowing rapid organoid screening.
Emission pathways and mitigation options for achieving consumption-based climate targets in Sweden
Authors: Morfeldt Johannes , Larsson Jörgen , Andersson David , Johansson Daniel J. A. , Rootzén Johan , Hult Cecilia , Karlsson Ida 
Published: September 2023

AbstractNational emission reduction targets under the Paris Agreement have a territorial focus, incentivizing mitigation actions domestically. Here we examine the theoretical basis for adopting complementary consumption-based net-zero emission targets and assess the consequences of adopting such proposed targets for Sweden. We apply scenario analyses based on a prospective lifecycle assessment framework. The framework is a hybrid of bottom-up simulations for passenger travel, construction and housing, and food, and top-down analyses for remaining consumption. In this work, we show how consumption-based climate targets may accentuate the need for new demand-side climate policies that contribute to reducing emissions along supply chains of products and services. Our scenario analysis suggests that combining advanced mitigation technologies with behavioral changes could reduce emissions from 9.8 tons of carbon dioxide equivalents per capita in 2019 to between 2.7 and 4.8 tons by 2045 for Swedish residents, depending on global decarbonization pathways.
Transcriptional profiling unveils molecular subgroups of adaptive and maladaptive right ventricular remodeling in pulmonary hypertension
Authors: Khassafi Fatemeh , Chelladurai Prakash , Valasarajan Chanil , Nayakanti Sreenath Reddy , Martineau Sandra , Sommer Natascha , Yokokawa Tetsuro , Boucherat Olivier , Kamal Aryan , Kiely David G. , Swift Andrew J. , Alabed Samer , Omura Junichi , Breuils-Bonnet Sandra , Kuenne Carsten , Potus Francois , Günther Stefan , Savai Rajkumar , Seeger Werner , Looso Mario , Lawrie Allan , Zaugg Judith B. , Tello Khodr , Provencher Steeve , Bonnet Sébastien , Pullamsetti Soni Savai 
Published: September 2023

AbstractRight ventricular (RV) function is critical to prognosis in all forms of pulmonary hypertension. Here we perform molecular phenotyping of RV remodeling by transcriptome analysis of RV tissue obtained from 40 individuals, and two animal models of RV dysfunction of both sexes. Our unsupervised clustering analysis identified ‘early’ and ‘late’ subgroups within compensated and decompensated states, characterized by the expression of distinct signaling pathways, while fatty acid metabolism and estrogen response appeared to underlie sex-specific differences in RV adaptation. The circulating levels of several extracellular matrix proteins deregulated in decompensated RV subgroups were assessed in two independent cohorts of individuals with pulmonary arterial hypertension, revealing that NID1, C1QTNF1 and CRTAC1 predicted the development of a maladaptive RV state, as defined by magnetic resonance imaging parameters, and were associated with worse clinical outcomes. Our study provides a resource for subphenotyping RV states, identifying state-specific biomarkers, and potential therapeutic targets for RV dysfunction.
Electrowetting limits electrochemical CO2 reduction in carbon-free gas diffusion electrodes
Authors: Baumgartner Lorenz M. , Goryachev Andrey , Koopman Christel I. , Franzen David , Ellendorff Barbara , Turek Thomas , Vermaas David A. 
Published: September 2023

Electrowetting leads to flooding of silver-based, carbon-free gas diffusion electrodes for CO2 electrolysis.
A method for superfine pavement crack continuity detection based on topological loss
Authors: Jia Guohui , Lu Yang , Song Weidong , He Huan , Ma Rongchen 
Published: September 2023

AbstractDeep convolutional neural networks have become a popular tool for the automatic detection of pavement cracks. Despite their widespread use, the models currently available tend to emphasize pixel‐level classification accuracy for cracks, often overlooking the critical aspect of crack continuity. Addressing this gap, the authors’ research introduces a new method for the continuous detection of ultrafine pavement cracks, centred around the concept of topological loss. The authors’ novel approach hinges on expressing the disconnectivity between the background areas in an image through the connectivity of the cracks themselves. The proposed loss function accomplishes this by penalizing the unnecessary disconnection of the background areas, thereby minimizing the risk of false‐positive crack predictions. In this study, the authors trained and tested a crack‐detection network using the Crack500 dataset, as well as a new dataset specifically compiled for ultrafine crack analysis. The experimental outcomes indicate that the amalgamation of the mean squared error and the authors’ novel spatial topological loss function leads to a substantial improvement in the topological structure of ultrafine crack detection.
Value of [18F]FDG PET/CT in Diagnosis and Management of Spondylodiscitis
Authors: Lapa Constantin , Rischpler Christoph , Bundschuh Ralph Alexander , Dierks Alexander , Lang Sigmund , Wassilew Georgi , Alt Volker 
Published: September 2023

AbstractVertebral osteomyelitis is the third most common form of osteomyelitis in patients over 50 years of age.Whereas prompt (pathogen-directed) therapy is crucially associated with better outcomes, the heterogeneous clinical presentation of disease with unspecific symptoms often delays adequate
treatment initiation. Diagnosis requires a careful investigation of medical history, clinical findings and diagnostic imaging, including magnetic resonance imaging and nuclear medicine
techniques.Due to its high sensitivity, [18F]FDG PET/CT is becoming increasingly important in diagnosis and management of spondylodiscitis, especially in the postoperative setting with
presence of spinal hardware or other implantable devices in which MRI is limited.
Inequity in palliative care: class and active ageing when dying
Authors: Aamann Iben Charlotte , Dybbroe Betina 
Published: September 2023

AbstractThe purpose of this article is to explore social inequity in palliative care in Denmark, a country that is seen as a stronghold of universal health care. Using data stemming from 2 years of research, we have selected two cases for analysis. They consist of palliative conversations with two quite different patients. Drawing on sociocultural class theory, we find that the conversations involve social exclusion processes due to discourses of active ageing. We find that one privileged patient performs in line with an entrepreneurial self and is supported by the nurse. The other, disadvantaged patient performs in a passive way, and the conversation mainly alleviates the disrespect he has experienced in healthcare encounters. We conclude that palliative care reinforces classifying practices and distinctions between “good” and “bad” patients, when active ageing becomes a dominant factor. We suggest improving the quality and sensitivity of medical training and call for increased reflexivity among professionals on the unequal situation of patients in order to reduce inequity in access to health care when close to death.
Fostering transdisciplinary research for sustainability in the Global South: Pathways to impact for funding programmes
Authors: Schneider Flurina , Patel Zarina , Paulavets Katsia , Buser Tobias , Kado Jacqueline , Burkhart Stefanie 
Published: September 2023

AbstractAdvancing global sustainable development hinges on strengthening the connections between science, society, and policy, as well as addressing existing science inequalities. Research funding programmes play a pivotal role in this context, but little is known about how they can actively nurture required transformations of the science systems. In this paper, we investigate how science funders can actively promote science-society-policy interactions through transdisciplinary research (TDR) as a means to advance sustainable development in the Global South. Our primary focus is on the research funding programme “LIRA 2030 Africa”. Our research has revealed three closely intertwined pathways for cultivating TDR in this context: (1) Enabling African scientists to lead high-quality TDR projects, (2) empowering African scientists to pursue a career as TDR researchers, and 3) enhancing the context conditions for doing TDR in Africa. By scrutinising the advantages and challenges associated with these pathways and their associated activities, we conclude that fostering TDR in Africa necessitates a multifaceted approach. This approach entails a combination of measures, such as providing research grants, offering TDR and leadership training, fostering networks, developing institutions, and facilitating collaboration across various funders.
Modularized and scalable compilation for double quantum dot quantum computing
Authors: He Run-Hong , Xu Xu-Sheng , Byrd Mark S , Wang Zhao-Ming 
Published: September 2023

Abstract
Any quantum program on a realistic quantum device must be compiled into an executable form while taking into account the underlying hardware constraints. Stringent restrictions on architecture and control imposed by physical platforms make this very challenging. In this paper, based on the quantum variational algorithm, we propose a novel scheme to train an Ansatz circuit and realize high-fidelity compilation of a set of universal quantum gates for singlet-triplet qubits in semiconductor double quantum dots, a fairly heavily constrained system. Furthermore, we propose a scalable architecture for a modular implementation of quantum programs in this constrained systems and validate its performance with two representative demonstrations, the Grover’s algorithm for the database searching (static compilation) and a variant of variational quantum eigensolver for the Max-Cut optimization (dynamic compilation). Our methods are potentially applicable to a wide range of physical devices. This work constitutes an important stepping-stone for exploiting the potential for advanced and complicated quantum algorithms on near-term devices.
A novel approach to the green synthesis of zinc oxide nanorods using Thymus kotschyanus plant extract: effect of ammonium hydroxide and precursor concentration
Authors: Aspoukeh Peyman K , Barzinjy Azeez A , Hamad Samir M 
Published: September 2023

Abstract
This research introduces a pioneering green method for synthesizing zinc oxide nanorods (ZnO NRs) on a glass substrate using Thymus kotschyanus plant extract. The study delves into the intricate effects of ammonium hydroxide and precursor concentrations on the morphology, size, alignment, and crystalline structure of ZnO NRs. Through systematic experimentation, it was found that specific concentrations of these substances play vital roles in the formation and properties of the nanorods. Notably, a low concentration of the precursor coupled with a high concentration of ammonium hydroxide led to well-aligned hexagonal ZnO NRs with a remarkable aspect ratio. Variations in these concentrations were also found to influence the length, diameter, and alignment of the nanorods. The findings were corroborated using a diverse array of analytical techniques, including transmission and scanning electron microscopy, x-ray diffraction, UV–vis spectroscopy, and energy-dispersive x-ray analysis. The UV–vis spectra provided further insights into the optical properties and band gap energy of the ZnO NPs, while EDX analysis confirmed the elemental composition. This work represents a significant advancement in eco-friendly nanomaterial synthesis, providing detailed insights into the controlled fabrication of aligned ZnO NRs. Its innovative approach and extensive investigation into influencing factors make it a valuable contribution to the field of nanoscience.
A history of film music II
Authors: Kalinak Kathryn 
Published: September 2023

Abstract
Synchronization of music and image was achieved as early as 1894, and the quest for synchronization and its realization had long preceded the conversion to sound. “A history of film music II: 1927–70” looks at what happened after technologies in Europe and the United States allowed for a sound cinema and the response to sound cinema in global film industries around the world, including French, German, Soviet, Mexican, Brazilian, Chinese, Arab, Japanese, Turkish, and Hindi cinemas. A number of developments are covered, such as the rise of popular song and the bricolage score, the development of the background score, the genesis of the Hollywood film score, and the influence of jazz, serialism, and modernism. New developments since the publication of the first edition in 2010 include film music in Mongolia, Portugal, Cuba, and Spain.
A history of film music III
Authors: Kalinak Kathryn 
Published: September 2023

Abstract
The second half of the 20th century saw a transformation in film music. Popular song and background music began to converge in the compilation score. World music became more audible, and globalization influenced the funding, production, and distribution of films. “A history of film music III: 1970–present” looks at the new challenges and practices that confronted film music in the second half of the 20th century, which include the rise of auteurist directors, the development of an international film audience, the impact of experimental film, repressive political regimes, diminishing audiences and changing demographics, and evolving technologies. New material in this chapter covers minimalism, electronic scoring, the integration of sound design into the musical score, and numerous films and film scores since 2010, including Under the Skin, Baby Driver, Marie Antoinette, Roma, Crazy Rich Asians, and Dune.
Conclusion
Authors: Kalinak Kathryn 
Published: September 2023

Abstract
Film music continues to be an important part of film production in the early twenty-first century. In fact, its practice has become indispensable to the marketability of films in the United States and globally. Soundtracks often precede a film’s release and may bring in higher profits than the film itself. It is hard to imagine a film without any music whatsoever. The conclusion speculates on the future of film music as it ponders its connections to television, music videos, gaming, and the Internet. To what extent do these new media forms depend on music? What functions that music affords film might also apply to these new media?
The Court at work (2)
Authors: Greenhouse Linda 
Published: September 2023

Abstract
“The Court at work (2)” looks at the significance of the marble building the justices moved into in 1935. This permanent home had both practical and symbolic weight, communicating the Court’s role at the head of a coequal branch of government. The Court has been criticized for the choices it makes in constructing its docket as well as for its focus on the “litigated Constitution” rather than structural problems that may be beyond any court’s reach. While much of the work happens behind closed doors rather than in the open sessions, the Internet has brought the Court closer to the public, with audio files and transcripts available almost in real time.
The Court and the other branches
Authors: Greenhouse Linda 
Published: September 2023

Abstract
Is the phrase separation of powers misleading? “The Court and the other branches” looks at the Court in relation to the president and Congress. A more accurate description of the relationship among the branches might be “dynamic interaction,” with tensions arising inevitably among them. Sometimes these tensions cause limited disagreements. Some developments are more substantial, such as Congress’s attempts to limit the Supreme Court’s power or the power of federal courts in general. This ingrained and constitutionally based struggle about law-making authority is expressed in a cycle of interaction and reaction that shows no sign of ending and may be hard-wired into the system.