bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studi Review dalam Meningkatkan Hasil Belajar di Sekolah Dasar dalam Sebuah Penelitian Tindakan Kelas
Authors: Lailatuz Zahroh  , Indryani  , Hadiyanyo  
Published: February 2025

This research aims to review the influence of Classroom Action Research (PTK) on student learning outcomes at elementary school (SD) level. The method used in this research is a literature review study, by collecting and analyzing scientific articles related to the implementation of PTK in elementary schools. The data collection technique used is analysis, which will later function to collect relevant data and sources in this research. The type of data used is qualitative, chosen because the method applied is a literature study. From analysis of various sources, it was found that the implementation of CAR had a significant impact in improving student learning outcomes. This method allows teachers to identify learning problems, plan improvements, and evaluate the effectiveness of teaching strategies implemented on an ongoing basis. This study combines six literature studies with a Systematic Literature Review (SLR) approach to examine the influence of the Card Sort, Problem-Based Learning (PBL), Jigsaw, Course Review Horay, and Guided Discovery learning methods on achieving learning outcomes. The results of the analysis show that interactive and collaborative methods, such as Card Sort, Jigsaw, and PBL, are able to increase student participation, understanding, and learning motivation. Meanwhile, the influence of social media on learning outcomes emphasizes the important role of parents and teachers in guiding the use of social media to remain productive. Overall, active and collaborative learning methods and improvements to improve the quality of learning at the basic level.
Implementasi Technological Pedagogical and Content Knowledge (TPACK) dalam Penelitian Tindakan Kelas: Sebuah Studi Review
Authors: Ditami Ayu  , Hadiyanyo  , Indryani  
Published: February 2025

This study reviews the application of various innovative learning models in the context of 21st century education in Indonesia, with a focus on the application of Technological Pedagogical Content Knowledge (TPACK) and other cooperative learning methods. This study refers to the latest research (2020-2024) which examines the effectiveness of implementing TPACK in the Teacher Professional Education (PPG) program, Classroom Action Research (PTK) training oriented towards 21st century learning, as well as the use of creative digital learning media. like a webtoon comic. The method used in this research is a literature review study, by collecting and analyzing scientific articles related to the implementation of PTK in elementary schools. The data collection technique used is analysis, which will later function to collect relevant data and sources in this research. The type of data used is qualitative, chosen because the method applied is a literature study. The results of this study show that the application of TPACK and other innovative learning methods has a positive impact in increasing teacher competence, student interest and involvement, as well as student learning outcomes. Technology-based learning models such as TPACK and Problem Based Learning (PBL) strategies combined with the Talking Stick method, have been proven to be able to improve students' critical thinking skills and activity in learning. This study concludes that collaboration between technology and pedagogy in learning has an important role in building an education system that is responsive to the demands and challenges of the digital era.
Implementasi Model Make A Match untuk Meningkatkan Hasil Belajar IPA Siswa Kelas V SD Eka Tjipta Mandang Seruyan
Authors: Muryanto Deddy , Anjarwani Ratih 
Published: February 2025

This research aims to determine the learning outcomes of the make a match type cooperative learning model on student learning outcomes on temperature and heat material in class V semester II of SD Eka Tjipta Mandang Seruyan. This research is classroom action research (PTK) with the research subjects being class V students at SD Eka Tjipta. Data collection techniques through science learning tests. The test consists of 10 multiple choice questions and 5 essay questions. Analysis is obtained through observation and tests. Based on the results of observations, it shows that out of 41 students, 24 students were still below the KKM in Class V SD Eka Tjipta Mandang Seruyan, 24 students were below the KKM with a class average score of 59.27. The results of the research show that the make a match type cooperative learning model is effective in improving cycle 1 science learning outcomes, showing a student learning completion level of 68% with an average score of 70.61. In cycle 2, the level of completeness of student learning outcomes was 95% with an average score of 87.88. This research proves that the application of the make a match type cooperative learning model can improve science learning outcomes in class V at SD II Eka Tjipta Mandang Seruyan.
Komunikasi Pemasaran Word of Mouth Kelompok Belajar Harapan Bunda Kedungwuluh Purwokerto dalam Membangun Kepercayaan Klien
Authors: Purwanto Niken Meinica , Turistiati Ade Tuti , Perwita Adinna Islah 
Published: February 2025

Keberadaan Kelompok Belajar (KB) semakin meningkat baik di kota besar maupun kota kecil seperti Purwokerto. Perlu adanya strategi pemasaran yang tepat bagi KB untuk dapat bersaing dengan kompetitor lainnya dalam memikat calon klien. Salah satunya, strategi komunikasi pemasaran word of mouth yang dilakukan oleh Kelompok Belajar Harapan Bunda Kedungwuluh Purwokerto Barat atau yang dikenal dengan sebutan KB Harbund. Penelitian ini bertujuan untuk memahami dan mendeskripsikan komunikasi pemasaran word of mouth KB Harbund dalam membangun kepercayaan klien dari aspek harmony, acceptance dan participation simplicity. Penelitian ini menggunakan metode penelitian kualitatif deskriptif dengan teknik pengumpulan data secara snowball sampling, observasi, wawancara serta dokumentasi. Penelitian ini dikaji dengan teori kepercayaan klien dari Manfred Bruhn. Hasil penelitian menunjukkan bahwa word of mouth di KB Harbund berasal dari pihak internal dan eksternal KB Harbund. Dari pihak internal yaitu kepala sekolah dan guru-guru KB Harbund dengan KB Harbund menyosialisasikan kepada masyarakat akan pentingnya pendidikan anak usia dini dan menawarkan biaya sekolah yang murah, sementara dari pihak eksternal yaitu wali murid dan stakeholder dari KB Harbund dengan menceritakan dan merekomendasikan KB Harbund kepada calon klien. Word of mouth yang dilakukan ini berhasil membangun kepercayaan klien melalui program-program yang ada di KB Harbund, diantaranya program subsidi silang, program parenting, program outing class, program kesehatan, dan program konsultasi.
Kata kunci: Komunikasi Pemasaran Word of mouth; Teori Kepercayaan Klien Manfred Bruhn; Kelompok Belajar; KB Harbund Purwokerto
Towards a Socio-Cultural History of Experience: A Theoretical-Methodological Framework
Authors: Kokko Heikki , Harjula Minna 
Published: February 2025

This article focuses on two basic issues: how experiences are social and cultural, and how we can use experiences as an analytical lens in historical research. Kokko and Harjula develop their earlier social history-based approach to experiences by making cultural legitimation an explicit component of theoretical conceptualisation. They theorise how experiences construct socio-cultural reality by pointing out institutionalisation and legitimation as the processes that make experiences societally circulated, taken-for-granted socio-cultural structures. The dynamics of change are conceptualised as an interplay between cultural tradition, present experiences, and future expectations. The article presents methodological tools for historical research. The ‘layer of experience’ and ‘scene of experience’ are conceptualisations for contextual temporal and spatial analysis. By combining the analysis of expressions of experiences – ‘sediments’ – with the study of ‘scripts’ and ‘narratives’, Kokko and Harjula contribute to the recent discussion on the normative and narrative features of experience. They conclude by reflecting on the role of historical research in cultural legitimation.
Comparative analysis of retinal vascular structural parameters in populations with different glucose metabolism status based on color fundus photography and artificial intelligence
Authors: Chen Naimei , Zhu Zhentao , Gong Di , Xu Xinrong , Hu Xinya , Yang Weihua 
Published: February 2025

ObjectiveMeasure and analyze retinal vascular parameters in individuals with varying glucose metabolism, explore preclinical retinal microstructure changes related to diabetic retinopathy (DR), and assess glucose metabolism’s impact on retinal structure.MethodsThe study employed a cross-sectional design encompassing a 4-year period from 2020 to 2024. Fundus photographs from 320 individuals (2020–2024) were categorized into non-diabetes, pre-diabetes, type 2 diabetes mellitus (T2DM) without DR, and T2DM with mild-to-moderate non-proliferative DR (NPDR) groups. An artificial intelligence (AI)-based automatic measurement system was used to quantify retinal blood vessels in the fundus color photographic images, enabling inter-group parameter comparison and analysis of significant differences.ResultsBetween January 2020 and June 2024, fundus color photographs were collected from 320 individuals and categorized into four groups: non-diabetes (n = 54), pre-diabetes (n = 71), T2DM without overt DR (n = 144), and T2DM with mild-to-moderate NPDR (n = 51). In pairwise comparisons among individuals with pre-diabetes, T2DM without DR, and T2DM with mild-to-moderate NPDR. Fasting blood glucose (FBG), glycated hemoglobin (HbA1c), systolic blood pressure (SBP), and diastolic blood pressure (DBP) were significantly different (P &lt; 0.05). Within the T2DM population, FBG, HbA1c, age, SBP, and DBP were significant predictors for mild-to-moderate NPDR (P &lt; 0.05). Average venous branching number (branch_avg_v) was significantly different among pre-diabetes, T2DM without DR, and T2DM with mild-to-moderate NPDR groups. In patients with T2DM with mild-to-moderate NPDR, Average length of arteries (length_avg_a) and average length of veins (length_avg_v) increased, whereas branch_avg_v, average venous branching angle (angle_avg_v), average venous branching asymmetry (asymmetry_avg_v),overall length density (vessel_length_density), and vessel area density (vessel_density) decreased significantly (P &lt; 0.05). Logistic regression analysis identified length_avg_a, branch_avg_v, angle_avg_v, asymmetry_avg_v, vessel_length_density, and vessel_density as independent predictors of mild-to-moderate NPDR in patients with T2DM. Receiver Operating Characteristic (ROC) curve analysis demonstrated that length_avg_a, length_avg_v, branch_avg_v, angle_avg_v, asymmetry_avg_v, vessel_length_density, and vessel_density had diagnostic value for mild-to-moderate NPDR (P &lt; 0.05).ConclusionIn individuals diagnosed with T2DM, specific retinal vascular parameters, such as branch_avg_v and vessel_density, demonstrate a significant correlation with mild-to-moderate NPDR. These parameters hold promise as preclinical biomarkers for detecting vascular abnormalities associated with DR.
Genotype 3 is linked to worse liver disease progression in hepatitis C patients even after SVR following DAA therapy
Authors: Ran Xiping , Xu Yang , Wang Ying , Zeng Cheng , Gong Chen , Wang Ni , Cai Dachuan 
Published: February 2025

Background and aimsHCV genotype (GT) 3 is associated with rapid liver disease progression. However, the liver disease progression and its risk factors in patients with HCV GT 3 infection after sustained virological response (SVR) following direct-acting antivirals (DAAs) remain unclear. Therefore, we aimed to investigate the liver disease progression of patients with GT 3 after SVR.MethodsThis was a retrospective cohort study of patients with HCV infection who achieved SVR by DAAs. The clinical outcome was overall liver disease progression (OLDP), defined as newly diagnosed compensated liver cirrhosis, decompensated liver cirrhosis, or hepatocellular carcinoma. The incidence of OLDP was evaluated by Kaplan−Meier analysis. Cox regression analysis identified the risk factors for OLDP.ResultsA total of 409 patients (46.9% GT3) were followed for 43.7 (32.9, 58.7) months. The incidence of OLDP was higher in patients with GT 3 (4.63/100PY) than non-GT 3 (0.60/100PY; P &lt; 0.001). According to Cox multivariate analysis, GT 3 was significantly associated with OLDP (HR 6.41, 95% CI 1.82 - 22.56; P=0.004). The predictors of OLDP in patients with GT 3 were HCV recurrence (HR 12.15, 95% CI 3.18 - 46.46; P &lt; 0.001) and FIB-4 &gt; 3.25 (HR 16.40, 95% CI 1.03 - 39.81; P = 0.046) at baseline.ConclusionHCV GT 3-infected patients remain at a higher risk of OLDP even after achieving SVR by DAAs, especially patients with advanced liver fibrosis and at high risk for reinfection or virological late relapse.
Correlation between uterine microbiota and pregnancy outcomes of embryo transfer in overweight and obese women
Authors: Yan Ying , Li Ying , Wu Lingling , Zhang Yuxuan , Guo Hong , Ji Yazhong 
Published: February 2025

ObjectiveCurrently, it has been reported that uterine microbiota affected pregnancy outcomes in assisted reproductive technology, but little was known in obese women. Thus, this study aims to explore how body weight affects pregnancy outcomes by comparing the differences in uterine microbiota between women of normal weight and those with obesity or overweight.MethodsThe study included 45 embryo transfer cycles. Patients were divided into two groups based on body mass index (BMI): normal-weight group, BMI ≤23.9 kg/m² (Con group, n=31) and obesity/overweight group, BMI &gt;23.9 kg/m² (OwOb group, n=14). Microbial samples were collected from the catheter tips and analyzed using RNA Ribosomal 16S.ResultsIn 45 women, the β-human chorionic gonadotropin (β-hCG) positivity rate and clinical pregnancy rate 10-12 days after embryo transfer were higher in the Con group. At the genus level, the relative abundance of Lactobacillus in the Con group was 2.2 times higher than that in the OwOb group. The Alpha diversity in the OwOb group was significantly higher than in the Con group (p=0.028). After regrouping based on β-hCG results 10-12 days post-transfer, in the Con-negative group (the group with negative β-hCG in the Con group, n=16) the relative abundances of pathogenic bacteria such as Klebsiella (p&lt;0.001), Parasutterella (p=0.004), Dialister (p=0.01), and Gardnerella (p=0.029) were significantly higher than in the Con-positive group (the group with positive β-hCG in the Con group, n=15).ConclusionOverweight and obese women possess a distinct uterine microbiota, characterized by a lower relative abundance of Lactobacillus and an increased relative abundance of pathogenic bacteria, along with specific genera strongly associated with obesity. In individuals with higher BMI, pathogenic bacteria are more likely to impair endometrial receptivity, ultimately leading to adverse pregnancy outcomes. Therefore, modulating the uterine microbiota in overweight/obese women may improve assisted reproductive technology success rates.
Gut-brain axis mediated by intestinal content microbiota was associated with Zhishi Daozhi decoction on constipation
Authors: Fang Leyao , Yi Xin , Shen Junxi , Deng Na , Peng Xinxin 
Published: February 2025

BackgroundConstipation is a common digestive system disorder, which is closely related to the intestinal flora. Zhishi Daozhi decoction (ZDD) is a traditional Chinese medicine prescription used to treat constipation caused by indigestion. This study is to evaluate the efficacy of ZDD in treating constipation and to elucidate the underlying mechanism.MethodsIn this study, Kunming mice were administered a high-protein diet (HFHPD) and loperamide hydrochloride injections to induce constipation. The mice then received varying doses (2.4, 4.7, and 9.4 mg/kg) of ZDD for seven days. Following the sampling process, we measured fecal microbial activity. The levels of 5-hydroxytryptamine (5-HT), vasoactive intestinal peptide (VIP), and aquaporin-3 (AQP3) were quantified using enzyme-linked immunosorbent assay. Changes in the gut microbiota were evaluated through 16S rRNA gene sequencing. Additionally, we investigated the correlation between specific microbiota features and the levels of 5-HT, VIP, and AQP3.ResultsThe fecal surface of the mice in the model group (CMM) was rough and dry. The stool of mice in the low-dose ZDD group (CLD), medium-dose ZDD group (CMD), and high-dose ZDD group (CHD) exhibited a smoother texture, closely resembling that of the normal group (CNM). 5-HT levels in the CMM group were significantly lower than in the CNM, CLD, and CHD. VIP levels in the CMD were lower than in the other four groups, and AQP3 levels in CMM showed a decreasing trend. The fecal microbial activity of the CMM group was significantly higher than that of the other groups. Diversity analysis indicated that CMD and CHD treatments were more effective in restoring the intestinal microbiota structure. Potential pathogenic bacteria, including Clostridium, Aerococcus, Jeotgalicoccus, and Staphylococcus were enriched in CMM. In contrast, beneficial bacteria such as Faecalibacterium, Bacillaceae, and Bacillus were more prevalent in the CLD, CMD, and CHD. Correlation analysis revealed that Streptococcus and Enterococcus were positively correlated with VIP, while Succinivibrio showed a negative correlation with 5-HT.ConclusionsConstipation induced by HFHPD and loperamide hydrochloride disrupts the structure of the intestinal microbiota. ZDD appears to alleviate constipation, potentially through mechanisms linked to the brain-gut axis and its interaction with the intestinal microbiota. Among the treatment groups, the medium dose of ZDD demonstrated the most effective results.
A case series of patients with cardiac amyloidosis evaluated at a Colombian university hospital
Authors: López-Ponce de León Juan David , Granados-Álvarez Santiago , Arango-Ibanez Juan Pablo , Montero Echeverri Juan Manuel , Arteaga Tobar Andrea Alejandra , Garcia Andrea Facio-Lince , Rodas Cortes Yorlany , Gómez-Mesa Juan Esteban 
Published: February 2025

BackgroundIn Colombia, the characteristics of cardiac amyloidosis (CA)—including wild-type transthyretin amyloidosis (ATTRwt), immunoglobulin light chain amyloidosis (AL), and genetic variant transthyretin amyloidosis (ATTRv)—are underexplored.MethodsThis case series at a Colombian university hospital analyzed demographic, clinical, laboratory, radiological, and genetic data of CA patients diagnosed between 2018 and 2022. Patients with incomplete data underwent further testing.ResultsOf 24 identified patients, 14 were included after exclusions. The majority were male (73.3%), with an average age of 70.6 years. ATTRv and AL were equally prevalent (42.8%), followed by ATTRwt (14.2%). The p.Val142Ile TTR mutation was found among all ATTRv patients. Most presented with functional capacity NYHA I-II and common electrocardiographic findings included low voltage, atrial fibrillation, and first-degree AV block. Echocardiography and cardiac magnetic resonance imaging revealed ventricular hypertrophy, diastolic dysfunction, reduced longitudinal strain, and late myocardial enhancement.ConclusionsAL and ATTRv were the most common causes of CA followed by ATTRwt. This distribution, along with the clinical, and radiological characterization is consistent with previous reports of other regions. The p.Val142Ile mutation was the only one found in patients with ATTRv, suggesting a strong African genetic influence. These findings enhance our understanding of CA in the region.
Comparative analysis of ChatGPT and Gemini (Bard) in medical inquiry: a scoping review
Authors: Fattah Fattah H. , Salih Abdulwahid M. , Salih Ameer M. , Asaad Saywan K. , Ghafour Abdullah K. , Bapir Rawa , Abdalla Berun A. , Othman Snur , Ahmed Sasan M. , Hasan Sabah Jalal , Mahmood Yousif M. , Kakamad Fahmi H. 
Published: February 2025

IntroductionArtificial intelligence and machine learning are popular interconnected technologies. AI chatbots like ChatGPT and Gemini show considerable promise in medical inquiries. This scoping review aims to assess the accuracy and response length (in characters) of ChatGPT and Gemini in medical applications.MethodsThe eligible databases were searched to find studies published in English from January 1 to October 20, 2023. The inclusion criteria consisted of studies that focused on using AI in medicine and assessed outcomes based on the accuracy and character count (length) of ChatGPT and Gemini. Data collected from the studies included the first author's name, the country where the study was conducted, the type of study design, publication year, sample size, medical speciality, and the accuracy and response length.ResultsThe initial search identified 64 papers, with 11 meeting the inclusion criteria, involving 1,177 samples. ChatGPT showed higher accuracy in radiology (87.43% vs. Gemini's 71%) and shorter responses (907 vs. 1,428 characters). Similar trends were noted in other specialties. However, Gemini outperformed ChatGPT in emergency scenarios (87% vs. 77%) and in renal diets with low potassium and high phosphorus (79% vs. 60% and 100% vs. 77%). Statistical analysis confirms that ChatGPT has greater accuracy and shorter responses than Gemini in medical studies, with a p-value of &lt;.001 for both metrics.ConclusionThis Scoping review suggests that ChatGPT may demonstrate higher accuracy and provide shorter responses than Gemini in medical studies.