bluuebunny/crossref_metadata_2025_split huggingface dataset:
CAUSES OF DENTAL REMOVAL IN PSYCHIATRIC PATIENTS
Authors: Ilyina Roza , Muchamedzhanova Lubov 
Published: November 2023

According to the literature, in a mentally healthy population, the main cause of tooth extraction is complications of caries and periodontitis, mainly in elderly and senile patients. In patients with psychiatric pathology, many authors note the high prevalence of dental diseases and emphasize the need for tooth extraction.
The aim of the investigation was to study the structure of dental diseases requiring tooth extraction in psychiatric hospital patients.
Material and methods of research. Information was copied from 1812 dental records of patients who were on inpatient treatment at the V.N. Bekhterev RCPB in the period from 2014 to 2016 at the age of 16 to 82 years (879 men and 933 women). The main reason for hospitalization of most patients was the diagnosis of schizophrenia (59%). The statistical software package SPSS 13.0 (1999) was used for statistical processing of the results.
The results of the study. During the study period, the dental surgeons of the RCPB received 1812 patients who had 2187 teeth removed. Mostly, the tooth extraction operation was performed for chronic periodontitis (47.2%). The greatest number of removals for periodontitis was observed in elderly patients (57.1%). The smallest number of teeth removed due to periodontitis was observed in the group of middle-aged patients (45–59 years) and amounted to 36.3% of the total number of teeth removed. This is due to the predominance of chronic periodontitis in these patients, which is comparable to the indicators in patients without psychiatric pathology. In the group of elderly and senile patients, tooth extraction surgery for chronic periodontitis was performed in 49.3% of cases.
Conclusions. The main reason for tooth extraction in mentally ill patients was chronic periodontitis and its exacerbation – 47.2%. The average age of these patients was 59.16 ± 14.33 years in men and 52.91 ± 11.85 years in women. The predominance of chronic periodontitis in the structure of the causes of tooth extraction in patients of the middle age group indicates an early clinical manifestation of inflammatory and destructive changes in the periodontium.
The use of the video format as a teaching guide in university studies
Authors: Navarro-Ardoy Luis , Castro-Higueras Antonio , Monedero-Morales Carmen del Rocío 
Published: November 2023

This article presents a pilot experiment on subjects from three Social Sciences degrees at two public Andalusian universities. The aim is to analyze the teaching guides and their presentation to students as a means of communicating with them, primarily through the video format instead of the conventional written format. To this end, attractive, clear and relatable video teaching guides have been developed to present to students, aware of the success of short videos dominating digital social networks, especially among younger age groups. A knowledge test was given to 99 students on the subject contents, as well as a satisfaction test; the following information was processed through the SPSS program. The main conclusion is that students have a high degree of satisfaction and a better knowledge of the new video guide format than the conventional written model.
Received: 21 July 2022Accepted: 20 June 2023
Strategi Pengembangan Sumber Daya Manusia Bank BRI Melalui BRI Corporate University
Authors: NUR ELLYANAWATI ESTY RAHAYU  , DAMAR BUDI UTAMA  
Published: November 2023

Penelitian ini bertujuan untuk menjelaskan pengembangan pendidikan bagi SDM di industri perbankan yaitu Bank BRI melalui BRI Corporate University. Salah satu indutri perbankan yang telah memiliki Corporate University adalah Bank BRI. Pendekatan yang digunakan peneliti adalah dengan deskriptif-kualitatif melalui sumber data primer dan data sekunder. Sampel yang diambil adalah BRI Corporate University Regional Campus Yogyakarta yang membawahi wilayah DIY dan Jawa Tengah. Metode pengumpulan data di lokasi penelitian terhadap objek yang diteliti dengan cara : 1) Interview atau wawancara kepada pejabat Bank BRI Corporate University Regional Campus Yogyakarta 2). Observasi, yaitu dengan melakukan pengamatan langsung ke berbagai kegiatan yang menjadi objek penelitian di Bank BRI Corporate University Regional Campus Yogyakarta. Hasil penelitian menunjukkan bahwa pengembangan pendidikan SDM melalui BRI Corporate University memiliki keunggulan yaitu untuk 1) peningkatan pengetahuan dan teknologi, 2) memenangkan persaingan bisnis, 3) peningkatan karier pegawai, serta 4) mencapai efektifitas dan efisiensi biaya pendidikan. Strategi pengembangan SDM Bank BRI melalui BRI Corporate University dengan menggunakan 1) Platform pendidikan BRI Corporate University melalui self-learning dan in class learning 2) Metode pendidikan BRI Corporate University yaitu dengan metode on the job training, 3) klasifikasi program pendidikan BRI Corporate University melalui program enhancement dan development.
PENGARUH KOMPETENSI, MOTIVASI, KOMITMEN DAN KEDISIPLINAN TERHADAP KINERJA SUMBER DAYA MANUSIA DI PERUSAHAAN STARTUP
Authors: DINDA SUKMANINGRUM.,ST.,MM  , DR. DODI SETIAWAN RIATMAJA.,MBA  , DR. SUPARMONO.,M.SI  
Published: November 2023

Efisiensi seseorang daIam menyeIesaikan tugasnya memiIiki pengaruh yang signifikan terhadap kinerja keuangan suatu organisasi. Untuk menjadi sukses, seseorang harus memiIiki kuaIitas yang menunjukkan etos kerja yang kuat, seperti kompetensi, dorongan, disipIin diri, dan pengabdian. HaI ini memberikan tantangan bagi Perusahaan Startup di Yogyakarta daIam haI memotivasi tenaga kerjanya untuk menghasiIkan tenaga kerja yang memiIiki tingkat produktivitas internasionaI. Perusahaan Startup di Yogyakarta bertujuan untuk menghasiIkan karyawan yang memenuhi standar produktivitas internasionaI. Tujuan dari peneIitian ini adaIah untuk mendapatkan pemahaman yang Iebih baik tentang faktor-faktor yang berkontribusi terhadap tingkat dedikasi dan produktivitas SDM Perusahaan Startup di Yogyakarta sehingga kita dapat memperoIeh pemahaman yang Iebih baik tentang faktor-faktor yang berkontribusi terhadap keberhasiIan perusahaan dan peIatihan yang diberikan. karyawannya menerima. Besar sampeI peneIitian ini ditentukan dengan menggunakan seIuruh 250 orang karyawan Perusahaan Startup di Yogyakarta sebagai dasar perhitungan. PeneIitian ini mengumpuIkan data dari 132 partisipan dengan menggunakan metode yang disebut purposive random sampIing karena keterbatasan faktor seperti Iokasi dan waktu. Wawancara dengan responden diIakukan untuk mengumpuIkan informasi. Untuk mengatasi masaIah peneIitian dan pengujian hipotesis, digunakan anaIisis PartiaI Ieast Square (PIS) yang disertakan dengan program SmartPIS. Berdasarkan temuan sebuah badan peneIitian, adanya koreIasi antara 1) kompetensi dan komitmen, 2) motivasi dan komitmen, 3) disipIin diri dan komitmen, 4) kompetensi dan kinerja, 5) motivasi dan kinerja, 6) diri -disipIin dan kinerja, dan 7) kompetensi dan kepuasan kerja..
Kata Kunci: Kompetensi, Disiplin, Motivasi, Kinerja, Komitmen.
Physicochemical and Microbiological Quality and Safety of Brand Pasteurized Milk Produced and Sold in Bishoftu, Ethiopia
Authors: Alemu Tesfaye , Kebede Geda , Tadesse Yosef 
Published: November 2023

Abstract
The present study aimed to evaluate the physicochemical and microbiological quality and safety of pasteurized milk produced and sold in Bishoftu, Ethiopia. A total of 48 pasteurized milk samples were collected three brands of pasteurized milk. The overall mean of pasteurized milk were fat (3.08 ± 0.09%), protein (2.94 ± 0.06%), solid not fat (6.83 ± 0.17%), specific gravity (1.026 ± 0.00kg/l), add water (15.91 ± 1.85%), titratable acidity (0.16 ± 00%) and pH (6.64 ± 0.02). The overall mean of pasteurized milk were (log10 cfu/ml) aerobic mesophilic bacteria count (4.47 ± 0.10), total coliform count (2.05 ± 0.18), spore forming bacteria count (2.09 ± 0.10), yeast and mold count (2.00 ± 0.16) and E. coli (0.61 ± 0.06). The mean aerobic mesophilic bacteria count of pasteurized milk collected from Prime during non-fasting season (log10 cfu/ml 3.59 ± 0.23) was significantly lower than Mama and Holland dairy brands. The prevalence of salmonella in pasteurized milk the present study was nill. From this study it is possible to conclude that the physicochemical and microbiological quality and safety of raw milk collected B brand of pasteurized milk was substandard. Therefore, implementing strict milk quality control system and mandatory dairy product specification standard should be in place.
Assessment of extreme rainfall events for iFLOWS Mumbai in NCUM regional forecasting system
Authors: Thota Mohan S , Ashrit Raghavendra , Kondapalli Niranjan Kumar , Saha Upal , D Nagarjuna Rao , A Jayakumar , Mohandas Saji , V.S. Prasad 
Published: November 2023

Abstract

Multiple record-breaking rainfall events were observed along the Western Ghats (WG) during the recent monsoon seasons from 2019-2021. Rainfall amounts of up to >200 mm/day (Extreme rainfall, ER) were recorded especially over the Mumbai region (19.07N, 72.8E) causing flooding, landslides, damage to infrastructure and loss of life. Thus, to enhance the resilience of this region by providing early warning for flooding, the National Center for Medium-Range Weather Forecasting Unified model’s regional forecasting system (NCUM-reg) provides rainfall forecasts up to days (72-hour), which are utilized in the iFLOWS hydrological model. This study focuses on evaluating the performance of NCUM-reg forecasts during ER events. For this purpose, we have systematically performed model verification/assessment for 24 and 72-hour operational forecasts using the suite of observations (rain gauge, satellite) and newly generated NCMRWF’s regional reanalysis IMDAA. Key findings indicate the performance of a 4km regional model with explicit convection performing reasonably well in representing the key synoptic and dynamic features of the ER events. Quantitative assessment of the model forecasts shows the strength of in-situ observations. Taken together, results summarize the limitations of observations and stress the need for collective efforts of observations and systematic processbased verification methods to enhance the model's ability to forecast such extreme events.
Effects of narrow-wide row planting pattern on canopy photosynthetic characteristics, bending resistance and yield of soybean in maize-soybean intercropping
Authors: Gu Yan , Zheng Haoyuan , Li Shuang , Wang Wantong , Guan Zheyun , Li Jizhu , Mei Nan , Hu Wenhe 
Published: November 2023

Abstract

The shading of soybeans in the traditional intercropping mode is an essential factor affecting the lignin content and stem-bending resistance of soybeans. A reasonable strip of intercropping crops is becoming more crucial as mechanization levels improve. In this study, we aimed to investigate the effects of different row ratios and planting patterns on canopy photosynthesis, stem bending resistance, cellulose, hemicellulose, lignin, and related enzyme activities of soybean in a maize-soybean intercropping system that uses two patterns and four intercropping ratios. Compared with the uniform-ridge planting pattern of soybeans, the narrow-wide-row spacing pattern significantly improved the leaf area index (LAI), photosynthetic active radiation (PAR), and light transmittance ratio. On the other hand, the values of stem bending resistance, the content of cellulose, hemicellulose, lignin, phenylalanine ammonia-lyase (PAL), tyrosine ammonia-lyase (TAL), and cinnamyl alcohol dehydrogenase (CAD) activities also significantly increased, and the effect of D-M4S6 was the most significant of these treatments. The D-M6S6 treatment produced the highest yield among the different treatments. Therefore, based on the planting pattern of narrow-wide-row maize-soybean intercropping, four rows of maize and six rows of soybean were more effective in improving the lodging resistance of soybean in the semi-arid region of western China.
Analysis of Horizontal Gas-liquid Intermittent Flow Sub-Regimes Transitions: Physical Mechanisms and Flow Maps
Authors: Arabi Abderraouf , salhi Yacine , Zenati Youcef , Si-Ahmed El-Khider , Legrand Jack 
Published: November 2023

Abstract
These recent years, several experimental investigations were carried out on horizontal gas-liquid two-phase sub-regimes including plug, Less Aerated Slug (LAS) and Highly Aerated Slug (HAS) flows. Such classification is based on the shape of the elongated bubble/liquid slug interface as well as the aeration in the liquid slugs.
In this paper, an extensive experimental visualization was performed using air-water mixture in a 30 mm ID horizontal pipe covering a total of 189 operating conditions. It was reported, for the first time, that each sub-regime had a specific mechanism of aeration of the liquid slug flow. For instance, the presence of gas bubbles within liquid slugs, in case of plug flow, is due to the interfacial shear induced waves mechanism. The transitions to LAS and HAS flows are accompanied by the appearance of shearing-off and scooping mechanisms of bubbles, in the liquid film, into the liquid slug, respectively. In addition, the reported flow transition lines, as well as those existing in the literature, were analyzed using different existing coordinate systems. This analysis showed that the X-T system is the most suitable for predicting the three flow sub-regimes.
Moving from Transaction to Transformation to Address Non-Medical Drivers of Health: A thematic analysis of case notes from Community Health Workers
Authors: Poulos Natalie S. , Price Daniel , Paz Cindy , Mandell Dorothy J. 
Published: November 2023

Abstract

Background
Community Health Workers (CHWs) are frontline public health workers who are trusted community members and vital connectors to services that can address the major non-medical drivers of health. This study aims to examine the experiences of CHWs who are providing immediate and critical support to clients with health and social service needs to better understand how CHWs are supporting clients' development of strategies to address non-medical drivers of health.
Methods
Case notes from 95 high-risk clients who were seen by six community-based CHWs were included in the sample. All clients seen by these CHWs between March 2021 to July 2022 are included. Reflexive thematic analysis was used to identify themes that connected the experiences of CHWs.
Results
Two themes were identified. The first theme highlights the importance of trust between the CHW and the client to support change in non-medical social drivers of health. Case notes suggest trust is built in multiple ways including maintaining existing relationships within the community, approaching clients with compassion, and having a deep knowledge of the community. Trust between the CHW and the client allowed the CHW to better support the client to receive or enroll in services that could provide long-term change. The second theme focuses on the need for CHWs to move from a focus on crisis intervention to long-term behavior change among clients. Instances of long-term change are present in the data, yet it does not happen as frequently as it could or as frequently as CHWs hope that it would.
Conclusions
CHWs are providing instrumental support, while still struggling to function as agents of behavior change for clients. To improve the ability of CHWs to facilitate clients’ long-term behavior change, CHWs need to feel supported and encouraged to take time for trust building. Trust allowed CHWs to make the greatest impact and transformation of non-medical drivers of health.
Global profiling of protein S-palmitoylation in the second-generation merozoites of Eimeria tenella
Authors: Qu Zigang , Li Yuqiong , Li Wenhui , Zhang Nianzhang , Olajide Joshua Seun , Mi Xiaoyun , Fu Baoquan 
Published: November 2023

Abstract

The intracellular protozoan Eimeria tenella is responsible for avian coccidiosis which is characterized by host intestinal damage and death. During developmental cycle, E. tenella undergoes versatile transitional stages such as oocyst, sporozoites, merozoites as well as gametocytes. These developmental transitions involved changes in cell shape and cell size requiring cytoskeletal remodeling and changes in membrane proteins, which may require transcriptional and translational regulations as well as post-translational modification of proteins. Palmitoylation is a post-translational modification (PTM) of protein that orchestrates protein targeting, folding, stability, regulated enzymatic activity and even epigenetic regulation of gene expression. Previous research revealed that protein palmitoylation play essential role in Toxoplasma gondii, Trypanosoma cruzi, Trichomonas vaginalis and several Plasmodium parasites. Until now, there is little information on the enzymes related to palmitoylation and role of protein palmitoylation in E. tenella. Therefore, a palmitome of the second-generation merozoite of E. tenella was investigated. We identified a total of 2569 palmitoyl-sites that were assigned to 2145 palmitoyl-peptides belonging to 1561 protein-groups that participated in biological processes including parasite morphology, motility and host cell invasion. In addition, RNA biosynthesis, protein biosynthesis, folding, proteasome-ubiquitin degradation and enzymes involved in PTMs, carbohydrate metabolism, glycan biosynthesis and mitochondrial respiratory chain as well as vesicle trafficking were identified. The study allowed us to decipher the broad influence of palmitoylation in E. tenella biology, and thus lay a solid foundation to interpret its roles in the pathobiology of E. tenella infection. Raw data are publicly available at iProX with the dataset identifier PXD045061.
Factors affecting sweet potato (Ipomoea batatas (L.) Lam.) production practices in Northern and Southern Ethiopia
Authors: Aldow Ahmed , Feyissa Getachew Sime 
Published: November 2023

Abstract

Sweet potato (Ipomoea batatas (L.) Lam.) is a potential food security crop in the crop–livestock production systems for subsistence smallholder farmers in sub-Saharan Africa. This study assessed the social, ecological, and economic factors that influence sweet potato production in selected districts in Northern and Southern Ethiopia. The research site was stratified into low, middle, and high altitudes. A mixed method, consisting of quantitative and qualitative approaches, was used for data collection. A quantitative questionnaire was prepared and distributed to randomly selected farmer households, followed by qualitative in-depth interviews of key informants from research institutions, local agricultural offices, and researchers working in the study areas. In addition, informal interviews, transect walks, participation in planting, and discussions were used. In both sites, pests, diseases, drought, and lack of adaptable cultivars for different agro-ecological conditions influenced sweet potato production. In Northern Ethiopia, lack of adequate sweet potato knowledge of production practices and planting materials limited farmers from planting the crop widely. In Southern Ethiopia, farmers lost their sweet potato landraces because of the adoption and shifting to cultivating new high-yielding cultivars of sweet potato. This study suggests that farmers’ awareness and knowledge on the available cultivars and landraces as well as the relevant agronomical practices and performances should be improved. Moreover, participatory breeding programs for droughts, pests, and diseases tolerant, and nutrient rich and high - yielding cultivars are commendable.
MUC3A promotes the progression of Cholangiocarcinoma through the MAPK/ERK pathway
Authors: 冯 白洁 , 苏 伟 , Hu Lina , yu minghua 
Published: November 2023

Abstract
Aim
Cholangiocarcinoma (CCA) is the most common malignant tumor of the bile ducts. Due to its anatomical location, growth pattern, and lack of clear diagnostic criteria, it presents diagnostic challenges. Exploring its occurrence and development to find early markers and treatment targets is of great significance.
Methods
To determine whether Mucin 3A (MUC3A) can regulate the occurrence and development of cholangiocarcinoma cells and its mechanism, we constructed stable transfections of KONC (transfection negative control group) and MUC3A-KO1 and KO2 (transfection MUC3A knockout vectors) lentivirus in RBE cell lines. We investigated the effect of MUC3A on the proliferative capacity of cholangiocarcinoma cells using the CCK-8 assay and colony formation assay. The regulatory effect of MUC3A on the cell cycle of cholangiocarcinoma cells was examined using flow cytometry. The impact of MUC3A on the invasion and migration of cholangiocarcinoma cells was observed through scratch and Transwell assays. Additionally, the mechanism by which MUC3A regulates proliferation and metastasis of cholangiocarcinoma was explored using Western blot.
Results
MUC3A promotes the proliferation of cholangiocarcinoma cells by regulating the cell cycle. Additionally, MUC3A enhances the invasion and migration of cholangiocarcinoma cells by regulating the epithelial-mesenchymal transition(EMT). Furthermore, MUC3A regulates the proliferation and metastasis of cholangiocarcinoma cells through the ERK signaling pathway.
Conclusions
This study demonstrates that MUC3A regulates the proliferation and metastasis of cholangiocarcinoma cells through the ERK signaling pathway.
Long term results of a prospective multicenter obervational study on the use of anti-human T-lymphocyte immunoglobulin (ATLG) in unrelated donor transplantation (ATOS study)
Authors: Finke Jürgen , Schmoor Claudia , Ayuk Francis , Hasenkamp Justin , Verbeek Mareike , Wagner-Drouet Eva , Biersack Harald , Schäfer-Eckart Kerstin , Wolf Dominik , Stuhler Gernot , Reibke Roland , Schmid Christoph , Kaufmann Martin , Eder Matthias , Bertz Hartmut , Grichina Olga 
Published: November 2023

Abstract
ATOS is a prospective observational study evaluating the outcome of patients receiving anti-human T-lymphocyte immunoglobulin (ATLG) in unrelated donor transplantation. Primary endpoint was severe GvHD and relapse-free survival (SGRFS). GvHD prophylaxis consisted of ATLG and CSA/ MTX or MMF. Outcome was compared to the ATLG arm of our prospective randomized phase III multicenter trial trial (RCT).1, 2 165 patients with haematological malignancies were included. ATLG dose differed between centers (median total ATLG dose of 46 (IQR 32–60, range 15–91) mg/kg). Median follow-up was 70 months. As compared to the ATLG arm of our RCT, patients in ATOS were older, had a more advanced disease status, reduced intensity conditioning, HLA 10/10 match and PBSC transplantation were more frequent, given median ATLG dose was lower, and incidences of acute GvHD °III-IV (0.13), relapse (0.34), non-relapse mortality (0.23), and overall survival rates (0.52) were similar after 5 years. After adjusting for baseline differences, the largest difference in outcome was seen with respect to severe chronic GvHD (ATOS vs ATLG arm RCT: hazard ratio 2.79 [1.20, 6.51], p = 0.017). This long-term, multicenter, experience in routine clinical practice confirms the GvHD-protective effect of ATLG without compromising relapse and non-relapse mortality rates. Clinical Trial Registry: German clinical trials register DRKS00004581