bluuebunny/crossref_metadata_2025_split huggingface dataset:
Simultaneous secondary electron microscopy in the scanning transmission electron microscope with applications for in situ studies
Authors: San Gabriel Mia L , Qiu Chenyue , Yu Dian , Yaguchi Toshie , Howe Jane Y 
Published: February 2024

Abstract
Scanning/transmission electron microscopy (STEM) is a powerful characterization tool for a wide range of materials. Over the years, STEMs have been extensively used for in situ studies of structural evolution and dynamic processes. A limited number of STEM instruments are equipped with a secondary electron (SE) detector in addition to the conventional transmitted electron detectors, i.e. the bright-field (BF) and annular dark-field (ADF) detectors. Such instruments are capable of simultaneous BF-STEM, ADF-STEM and SE-STEM imaging. These methods can reveal the ‘bulk’ information from BF and ADF signals and the surface information from SE signals for materials &lt;200 nm thick. This review first summarizes the field of in situ STEM research, followed by the generation of SE signals, SE-STEM instrumentation and applications of SE-STEM analysis. Combining with various in situ heating, gas reaction and mechanical testing stages based on microelectromechanical systems (MEMS), we show that simultaneous SE-STEM imaging has found applications in studying the dynamics and transient phenomena of surface reconstructions, exsolution of catalysts, lunar and planetary materials and mechanical properties of 2D thin films. Finally, we provide an outlook on the potential advancements in SE-STEM from the perspective of sample-related factors, instrument-related factors and data acquisition and processing.
Effect of bolus materials on dose deposition in deep tissues during electron beam radiotherapy
Authors: Kong Dong , Wu Jia , Kong Xudong , Huang Jianfeng , Zhao Yutian , Yang Bo , Zhao Qing , Gu Ke 
Published: February 2024

Abstract
Several materials are utilized in the production of bolus, which is essential for superficial tumor radiotherapy. This research aimed to compare the variations in dose deposition in deep tissues during electron beam radiotherapy when employing different bolus materials. Specifically, the study developed general superficial tumor models (S-T models) and postoperative breast cancer models (P-B models). Each model comprised a bolus made of water, polylactic acid (PLA), polystyrene, silica-gel or glycerol. Geant4 was employed to simulate the transportation of electron beams within the studied models, enabling the acquisition of dose distributions along the central axis of the field. A comparison was conducted to assess the dose distributions in deep tissues. In regions where the percentage depth dose (PDD) decreases rapidly, the relative doses (RDs) in the S-T models with silica-gel bolus exhibited the highest values. Subsequently, RDs for PLA, glycerol and polystyrene boluses followed in descending order. Notably, the RDs for glycerol and polystyrene boluses were consistently below 1. Within the P-B models, RDs for all four bolus materials are consistently below 1. Among them, the smallest RDs are observed with the glycerol bolus, followed by silica-gel, PLA and polystyrene bolus in ascending order. As PDDs are ~1–3% or smaller, the differences in RDs diminish rapidly until are only around 10%. For the S-T and P-B models, polystyrene and glycerol are the most suitable bolus materials, respectively. The choice of appropriate bolus materials, tailored to the specific treatment scenario, holds significant importance in safeguarding deep tissues during radiotherapy.
Endoscopic reversal of the modified Long vertical gastroplasty
Authors: Abelman Talia , Skidmore Adam 
Published: February 2024

Abstract
Endoscopic techniques are revolutionizing bariatric surgery because of the significant risks that obesity places on both anaesthesia and surgery. Due to the high number of long-term complications that may be associated with bariatric surgery, and the relative safety of endoscopy compared to operative management, endoscopic methods for reversal of previous bariatric techniques are becoming the favoured approach. We describe the use of an endoscopic stent to assist with endoscopic reversal of a modified Long vertical gastroplasty. The modified Long vertical gastroplasty was a restrictive bariatric procedure that was effective to promote weight loss, but had adverse effects including dysphagia, reflux, indigestion and weight regain. The use of an adjunct stent not only treated the patient’s reflux by dilating the stricture but allowed for erosion of the sutures intra-luminally to be removed endoscopically. The endoscopic reversal of this technique is safe and helped to relieve the patient’s symptoms of reflux and dysphagia.
Travel health practices, behaviours and experiences of people living with type 1 diabetes
Authors: Tarlton Chloe , James Steven , Dixson Barnaby , Craft Judy 
Published: February 2024

Abstract

Introduction
There are limited data regarding the international travel history and preparation, as well as glycaemic control practices, risk behaviours and experiences of people with type 1 diabetes during travel. Our review aimed to address the research question: ‘What are the health practices, behaviours and experiences of people with type 1 diabetes when travelling?’

Methods
We conducted a mixed-methods narrative review using adapted review methods from the Centre for Reviews and Dissemination and standards developed by the Preferred Reporting Items for Systematic Reviews and Meta-Analysis. MEDLINE, Scopus, PubMed and CINAHL, and the reference lists of all eligible studies were searched.

Results
Nine records comprising of 11 studies were included, with data heralding from various countries, published between 1990 and 2022. We identified three main themes: travel preparation (type of travel, planning and advice seeking); issues related to air travel (airports and airport security, hypoglycaemia and hyperglycaemia, and insulin) and general travel-related issues (illness and medical treatment, type 1 diabetes management, and major concerns and barriers).

Conclusions
Our findings highlighted the lack of quality data regarding type 1 diabetes and travel within the extant literature, as well a pressing need for empirical studies to be undertaken and consensus guidelines developed to improve the travel experiences of people with type 1 diabetes. Unless change is made, people with type 1 diabetes will continue to experience preventable risk and harm while travelling.
Cervical Disc Displacement in Military Pilots
Authors: Tansey Patrick J , Janney Cory F , Jupiter Daniel C , Henriques Matthew , Alijanipour Pouya , Morrissey Patrick B 
Published: February 2024

ABSTRACT

Introduction
Cervical disc displacement (CDD) may disqualify pilots from flying and have a profound impact on military unit capability. The objective of this retrospective database review is to characterize the incidence and demographic predictors of symptomatic cervical spine disc displacement in pilots of fixed- and rotary-wing aircraft and ground-based controls.

Materials and Methods
The Defense Military Epidemiology Database was queried for first-occurrence ICD-9 code 722.0: CDD cases from 2007 to 2015. Injury count rates among aircraft groups and overall incidence per 1,000 person-years were calculated and standardized for age, gender, and military rank, and 95% confidence intervals (CIs) were compared to determine significance.

Results
There were 934 new cases of CDD among active duty U.S. Military pilots during the study period. The overall incidence of CDD in all pilots during this time frame was 2.715 per 1,000 person-years (95% CI, 2.603-2.830). Helicopter pilots had a significantly higher incidence compared to all other aircraft pilots and crew at 3.79 per 1,000 person-years (95% CI, 3.48-4.13). This finding remained statistically significant after standardizing for age, gender, and rank. Among all military officers, increasing age was a risk factor for CDD.

Conclusions
The U.S. Military helicopter pilots have an increased risk compared to fixed-wing pilots and non-pilot controls. CDD remains a rare, though career-threatening, condition. Increased education and awareness training are warranted for both helicopter pilots and flight physicians to recognize signs and symptoms of cervical pathology. Continued investigations into preventive measures to minimize injury and time unfit for flight are warranted.
The Holocaust as an (UN)Exceptional Phenomenon: Development and Change in the Lubavitcher Rebbe’s Outlook
Authors: Reiser Daniel 
Published: February 2024

Abstract
This article examines the evolution and transformation in the Lubavitcher Rebbe’s perspective concerning the Holocaust. It traces the Rebbe’s viewpoint on the Holocaust by analyzing his various insights and observations in his sermons and writings over the years, and highlights a significant shift in his stance whereby he reached the conclusion that the Holocaust is exceptional and does not fall into the terms of sin, punishment, or even Tikkun (metaphysical rectification)—concepts which he himself previously utilized in earlier stages of his life. In his most recent phase, the Lubavitcher Rebbe posited that the Holocaust is an unprecedented and exceptional occurrence, both on historical and theological grounds. This assertion is not commonly espoused by traditional Jewish theologians and orthodox rabbis, thus rendering the Lubavitcher Rebbe relatively distinctive.
The intestinal commensal fungus Wallemia mellicola enhances asthma in mice through Dectin-2
Authors: Kanj Amjad N , Guiance Irene Riestra , Kottom Theodore J , Schaefbauer Kyle J , Choudhury Malay , Limper Andrew H , Skalski Joseph H 
Published: February 2024

Abstract
Overgrowth of the fungus Wallemia mellicola in the intestines of mice enhances the severity of asthma. Wallemia mellicola interacts with the immune system through Dectin-2 expressed on the surface of myeloid and intestinal epithelial cells. Using Dectin-2-deficient mice, we show that the interaction of W. mellicola with Dectin-2 is essential for the gut-lung pathways, enhancing the severity of asthma in mice with W. mellicola intestinal dysbiosis. These findings offer better insight into dysbiosis-associated inflammation and highlight the role pattern recognition receptors have in immune recognition of commensal fungi in the gut, leading to alterations in immune function in the lungs.
Little evolution of dust emissivity in bright infrared galaxies from 2 &lt; z &lt; 6
Authors: Ward B A , Eales S A , Ivison R J , Arumugam V 
Published: February 2024

ABSTRACT
Variations in the dust emissivity index, $\beta$, within and between galaxies, are evidence that the chemistry and physics of dust must vary on large scales, although the nature of the physical and/or chemical variations is still unknown. In this paper, we estimate values of $\beta$ and dust temperature for a sample of 109 dusty star-forming galaxies (DSFGs) over the range, $2 \ \lt\ z \ \lt\ 6$. We compare the results obtained with both an optically thin model and a general opacity model, finding that our estimates of $\beta$ are similar between the models but our estimates of dust temperature are not. We find no evidence of a change in $\beta$ with redshift, with a median value of $\beta = 1.96$ for the optically thin model with a confidence interval (16–84 per cent) of 1.67 to 2.35 for the population. Using simulations, we estimate the measurement errors from our procedure and show that the variation of $\beta$ in the population results from intrinsic variations in the properties of the dust in DSFGs. At a fixed far-infrared luminosity, we find no evidence for a change in dust temperature, $T_{\textrm {dust}}$, with redshift. After allowing for the effects of correlated measurement errors, we find an inverse correlation between $\beta$ and $T_{\textrm {dust}}$ in DSFGs, for which there is also evidence in low-redshift galaxies.
Transient quasi-periodic oscillations in the gamma-ray light curves of bright blazars
Authors: Chen Junping , Yu Jinjie , Huang Weitian , Ding Nan 
Published: February 2024

ABSTRACT
Transient quasi-periodic oscillations (QPOs) are extremely interesting observational phenomena. However, the precise physical mechanisms leading to their generation are still hotly debated. We performed a systematic search for transient QPO signals using Weighted Wavelet Z-transforms on the gamma-ray light curves of 134 bright blazars with peak flux exceeding 1 × 10−6 ph cm−2 s−1 as monitored by Fermi-LAT. Artificial light curves were generated from the power spectral density and probability distribution functions of the original light curves to assess the significance level of transient QPO. We discuss several physical mechanisms that produce transient QPOs, with the helical jet model providing the best explanation. This study identified four new transient QPO events. Interestingly, repetitive transient QPOs are observed in PKS 0537-441, and nested transient QPOs are detected in PKS 1424−41. Additionally, we find that transient QPOs tend to occur in the flare state of the blazar. Finally, we estimate the incidence of transient QPO events to be only about 3 per cent.
The radio-loud fraction of quasars at z &gt; 6
Authors: Keller Pascal M , Thyagarajan Nithyanandan , Kumar Ajay , Kanekar Nissim , Bernardi Gianni 
Published: February 2024

ABSTRACT
Quasars at redshifts z &gt; 6 are an excellent probe of the formation and evolution of supermassive black holes in the early Universe. The population of radio-luminous quasars is of particular interest, as such quasars could potentially be used to study the neutral intergalactic medium during cosmic reionization via H i 21 cm absorption studies. However, the lack of deep radio observations of z &gt; 6 quasars leaves the population poorly constrained, and suitable candidates for an H i 21 cm absorption study have yet to be found. In this work, we present Jansky Very Large Array (VLA) 1–2 GHz radio continuum observations of 138 quasars at redshifts 6.0 ≤ z &lt; 7.6. We detect the radio continuum emission of the z = 6.1 quasar J1034−1425, with a 1.6 GHz flux density of $170\pm 36\, \mu$Jy. This quasar is radio-quiet with radio-loudness, R ≡ f5 GHz/fν, 4400 Å = 2.4 ± 0.5. In addition, we detect seven other quasars at z &gt; 6, which have previously been characterized in the literature at these frequencies. Using the full sample, we estimate the radio-loud fraction to be $3.8^{+6.2}_{-2.4}\ \hbox{per cent}$, where the uncertainties are 95 per cent confidence intervals. This is lower than recent estimates of the radio-loud fraction in the literature, but is still marginally consistent with no redshift evolution of the radio-loud fraction. We explore the undetected quasar population by stacking their continuum images at their optical positions and obtain a median stacked flux density of 13.8 ± 3.9 µJy and luminosity of log L5 GHz/(W Hz−1) = 24.2 ± 0.1.
Amalgame: cosmological constraints from the first combined photometric supernova sample
Authors: Popovic Brodie , Scolnic Daniel , Vincenzi Maria , Sullivan Mark , Brout Dillon , Chen Rebecca , Patel Utsav , Peterson Erik R , Kessler Richard , Kelsey Lisa , Sanchez Bruno O , Bailey Ava Claire , Wiseman Phil , Toy Marcus 
Published: February 2024

ABSTRACT
Future constraints of cosmological parameters from Type Ia supernovae (SNe Ia) will depend on the use of photometric samples, those samples without spectroscopic measurements of the SNe Ia. There is a growing number of analyses that show that photometric samples can be utilized for precision cosmological studies with minimal systematic uncertainties. To investigate this claim, we perform the first analysis that combines two separate photometric samples, SDSS and Pan-STARRS, without including a low-redshift anchor. We evaluate the consistency of the cosmological parameters from these two samples and find they are consistent with each other to under 1σ. From the combined sample, named Amalgame, we measure ΩM = 0.328 ± 0.024 with SN alone in a flat ΛCDM model, and ΩM = 0.330 ± 0.018 and w = $-1.016^{+0.055}_{-0.058}$ when combining with a Planck data prior and a flat wCDM model. These results are consistent with constraints from the Pantheon+ analysis of only spectroscopically confirmed SNe Ia, and show that there are no significant impediments to analyses of purely photometric samples of SNe Ia. The data and results are made available at https://github.com/bap37/AmalgameDR.
Understanding the association between fatigue and neurocognitive functioning in patients with glioma: A cross-sectional multinational study
Authors: Röttgering Jantine G , Taylor Jennie W , Brie Melissa , Luks Tracy , Hervey-Jumper Shawn L , Phan Stephanie , Bracci Paige M , Smith Ellen , De Witt Hamer Philip C , Douw Linda , Weyer-Jamora Christina , Klein Martin 
Published: February 2024

Abstract

Background
Fatigue and neurocognitive impairment are highly prevalent in patients with glioma, significantly impacting health-related quality of life. Despite the presumed association between these two factors, evidence remains sparse. Therefore, we aimed to investigate this relationship using multinational data.

Methods
We analyzed data on self-reported fatigue and neurocognitive outcomes from postoperative patients with glioma from the University of California San Francisco (n = 100, UCSF) and Amsterdam University Medical Center (n = 127, Amsterdam UMC). We used multiple linear regression models to assess associations between fatigue and seven (sub)domains of neurocognitive functioning and latent profile analysis to identify distinct patterns of fatigue and neurocognitive functioning.

Results
UCSF patients were older (median age 49 vs. 43 years, P = .002), had a higher proportion of grade 4 tumors (32% vs. 18%, P = .03), and had more neurocognitive deficits (P = .01). While the number of clinically fatigued patients was similar between sites (64% vs. 58%, P = .12), fatigue and the number of impaired neurocognitive domains were not correlated (P = .16–.72). At UCSF, neurocognitive domains were not related to fatigue, and at Amsterdam UMC attention and semantic fluency explained only 4–7% of variance in fatigue. Across institutions, we identified four distinct patterns of neurocognitive functioning, which were not consistently associated with fatigue.

Conclusions
Although individual patients might experience both fatigue and neurocognitive impairment, the relationship between the two is weak. Consequently, both fatigue and neurocognitive functioning should be independently assessed and treated with targeted therapies.
Legislative Intent and Agency: A Rational Unity Account
Authors: Collins Stephanie , Tan David 
Published: February 2024

Abstract
Realist theories of legislative intent can be divided between aggregative theories (on which legislative intent is what some proportion of legislators intend) and common intent theories (on which legislative intent is a unanimous intent among legislators). In this article, we advance and defend an alternative realist conception of legislative intent: the rational unity account. On this account, the legislature is an agent with a distinctive ‘rational point of view’—a concept we adopt from social ontology. The legislature’s rational point of view is shaped by its procedures and structures, in ways not determined by either a common intention held by legislators or an aggregation of the intentions of legislators. We explain how our view improves on existing accounts. We then apply it to three cases to demonstrate its implications for legal interpretation. Importantly, on the proposed account, legislative intent can depart from what individual legislators think or know.
Effects of Group Exercise on Motor Function and Mobility for Parkinson Disease: A Systematic Review and Meta-Analysis
Authors: Palm Diana , Swarowsky Alessandra , Gullickson Mackenzie , Shilling Holly , Wolden Mitch 
Published: February 2024

Abstract

Objective
Parkinson disease (PD) is associated with a predictable decline in motor function and mobility that is commonly managed with exercise. There is a limited understanding of the effects of group exercise compared to individual exercise (IE) and usual care (UC) on motor function and mobility. Our purpose was to investigate the effects of group exercise compared to IE and UC on motor function and mobility for people with PD.

Methods
A systematic review and meta-analysis was performed with randomized control trials that investigated the effects of group compared with IE and UC on motor function and mobility for people with PD. A systematic search was performed in PubMed, EBSCO, and Science Direct databases. Methodological quality was assessed using the Cochrane Grading of Recommendations Assessment, Development, and Evaluation approach.

Results
Twenty-three studies assessed at least 1 mobility-related outcome measure, met our inclusion criteria, and were included in quantitative analysis. There was no significant difference on motor function and mobility between group exercise and IE for all standardized outcome assessment meta-analyses. Motor function and mobility were significantly improved with group exercise compared to UC in 9 of 11 standardized outcome assessment meta-analyses. Results were based upon low to moderate quality of evidence.

Conclusion
Based upon low to moderate quality of evidence, group exercise has a similar to larger effect as IE and UC on improving motor function and mobility for people with PD. When used in combination with skilled physical therapy, group exercise may be an appropriate adjunct to individualized physical therapy to maximize mobility and function.

Impact
Long-term adherence to exercise is essential to maintain mobility and motor function for people with PD. Our study suggests group exercise is as effective as IE and may be an appropriate option to encourage long-term adherence related to increased access, socialization, and accountability.
Differences in management approaches for lupus nephritis within the UK
Authors: Ibrahim Sara T , Edwards Christopher J , Ehrenstein Michael R , Griffiths Bridget , Gordon Caroline , Hewins Peter , Jayne David , Lightstone Liz , McLaren Zoe , Rhodes Benjamin , Vital Edward M , Reynolds John A 
Published: February 2024

Abstract

Objectives
Outcomes of therapy for LN are often suboptimal. Guidelines offer varied options for treatment of LN and treatment strategies may differ between clinicians and regions. We aimed to assess variations in the usual practice of UK physicians who treat LN.

Methods
We conducted an online survey of simulated LN cases for UK rheumatologists and nephrologists to identify treatment preferences for class IV and class V LN.

Results
Of 77 respondents, 48 (62.3%) were rheumatologists and 29 (37.7%) were nephrologists. A total of 37 (48.0%) reported having a joint clinic between nephrologists and rheumatologists, 54 (70.0%) reported having a multidisciplinary team meeting for LN and 26 (33.7%) reported having a specialized lupus nurse. Of the respondents, 58 (75%) reported arranging a renal biopsy before starting the treatment. A total of 20 (69%) of the nephrologists, but only 13 (27%) rheumatologists, reported having a formal departmental protocol for treating patients with LN (P &lt; 0.001). The first-choice treatment of class IV LN in pre-menopausal patients was MMF [41 (53.2%)], followed by CYC [15 (19.6%)], rituximab [RTX; 12 (12.5%)] or a combination of immunosuppressive drugs [9 (11.7%)] with differences between nephrologists’ and rheumatologists’ choices (P = 0.026). For class V LN, MMF was the preferred initial treatment, irrespective of whether proteinuria was in the nephrotic range or not. RTX was the preferred second-line therapy for non-responders.

Conclusion
There was variation in the use of protocols, specialist clinic service provision, biopsies and primary and secondary treatment choices for LN reported by nephrologists and rheumatologists in the UK.