bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Rasio Keuangan Untuk Menilai Kinerja Keuangan Lembaga Perkreditan Desa (LPD) Desa Adat Ngis
Authors: Tiaswari Ni Made Tia Swari , Gede Adi Yuniarta  
Published: December 2023

Penelitian ini bertujuan untuk menilai kinerja keuangan pada LPD Desa Adat Ngis pada tahun 2018-2021. Penelitian ini adalah penelitian kuantitatif. Data yang digunakan adalah data sekunder, teknik pengumpulan data dilakukan dengan metode dokumentasi. Objek penelitian ini adalah analisis rasio keuangan untuk menilai kinerja keuangan.Data yang digunakan dalam penelitian ini yaitu laporan keuangan LPD Desa Adat Ngis tahun 2018-2021. Teknik analisis data yang digunakan adalah analisis deskriptif kuantitatif. Hasil penelitian menunjukkan current ratio LPD Desa Adat Ngis 4 tahun terakhir menggambarkan bahwa posisi kinerja keuangan LPD Desa Adat Ngis berada pada posisi kurang baik. Hasil debt to asset ratio 4 tahun terakhir menggambarkan bahwa posisi kinerja keuangan LPD Desa Adat Ngis berada pada kriteria sangat kurang baik. Hasil net profit margin LPD Desa Adat Ngis 4 tahun terakhir berada pada kriteria sangat baik. Hasil total assets turn over 4 tahun terakhir LPD Desa Adat Ngis berada pada kriteria sangat kurang baik.
PENGARUH KADAR D-DIMER, KREATININ SERUM, DAN JUMLAH LIMFOSIT ABSOLUT TERHADAP DERAJAT KEPARAHAN PASIEN COVID-19 KOMORBID CHRONIC KIDNEY DISEASE
Authors: Maharani Rahmi Annisa , Nurhyatun Evi , Harioputro Dhani Redhono 
Published: December 2023

ABSTRACT
COVID-19 is an infectious respiratory disease caused by infection SARS-CoV-2. Abnormal kidney function is associated with increased morbidity and mortality in COVID-19 patients. D-dimer levels, serum creatinine, and ALC can be used as markers of inflammation to determine the severity of COVID-19 comorbid chronic kidney disease (CKD). However, there are not many studies on this subject. This study aims to determine the impact of D-dimer, serum creatinine, and Absolute Lymphocyte Count (ALC) on the severity of COVID-19 comorbid CKD. This study uses an analytic observational method with a cross sectional approach from medical record data. The study population included COVID-19 patients with comorbid CKD at RS X Surakarta, who was examined for D-dimer levels, serum creatinine, and absolute lymphocyte counts, using purposive sampling and sample consisted of 53 patients. Bivariate analysis using Spearman’s Rank test obtained p value of D-dimer, serum creatinine, absolute lymphocyte counts 0,002; 0,042; 0,455. Multivariate analysis using multiple logistics regression showed that D-dimer OR=28,521 and serum creatinine OR=5,650, with a Nagelkerke R Square value of 0,338. There is an impact of D-dimer and serum creatinine levels on the severity of COVID-19 patients with CKD.

ABSTRAK
COVID-19 adalah penyakit pernapasan menular akibat infeksi virus SARS-CoV-2. Penyakit ginjal merupakan salah satu komorbid terbanyak pasien COVID-19, fungsi ginjal yang tidak normal berhubungan dengan peningkatan angka morbiditas dan mortalitas pasien COVID-19. Penelitian ini bertujuan untuk mengetahui pengaruh antara D-dimer, kreatinin serum, dan jumlah limfosit absolut terhadap derajat keparahan COVID-19 dengan komorbid chronic kidney disease (CKD). Penelitian ini menggunakan metode observasional analitik dengan pendekatan cross sectional dari data rekam medis. Populasi penelitian meliputi pasien COVID-19 dengan komorbid CKD di RS X Surakarta yang dilakukan pemeriksaan kadar D-dimer, kreatinin serum, dan jumlah limfosit absolut dengan teknik sampling purposive sampling didapatkan sebanyak 53 sampel. Analisis bivariat menggunakan uji korelasi Rank Spearman dan didapatkan nilai p D-dimer, kreatinin serum, jumlah limfosit absolut dengan keparahan COVID-19 masing-masing 0,002; 0,042; 0,455. Analisis multivariat menggunakan uji regresi logistik berganda dan didapatkan nilai OR D-dimer dan kreatinin serum masing-masing 28,521 dan 5,650 dengan nilai Nagelkerke R Square 0,338. Kesimpulan penelitian ini bahwa Kadar D-dimer dan kreatinin serum berpengaruh terhadap derajat keparahan pasien COVID-19 dengan komorbid CKD.
PERBEDAAN KARAKTERISTIK PEKERJA DAN BIOMARKER PAPARAN LINGKUNGAN KERJA PADA PEKERJA BENGKEL LAS DAN KANTOR
Authors: Roestijawati Nendyah , Prihatno MM Rudi , Hidayat M. Zaenuri Syamsu , Wibowo Yudhi , Krisnansari Diah 
Published: December 2023

ABSTRACT
Occupational diseases are caused by the interaction of workers, workload, and work environment factors. This study aims to determine the correlation of worker factors with biomarkers of occupational exposure MT1a, GSTp1, and PSA. The research design used was comparative cross-sectional. The research subjects were 30 welding workers and 30 administrative office employees who were taken by purposive sampling. The variables studied were worker factors such as age and BMI, levels of the enzyme GSTp1, MT1a and PSA. Measurement of GSTp1, MT1a, and PSA in blood was performed using the sandwich ELISA method. Data analysis was performed using the Mann-Whitney test. The results of the study found that there were significant differences in age, BMI, and PSA levels in the two groups. There is no differences in GSTp1 and MT1a level between groups. We concluded that the PSA levels of the group of office workers were higher than those of the group of welding workshop workers, perhaps because the average age was older.

ABSTRAK
Penyakit akibat kerja disebabkan oleh adanya interaksi faktor pekerja, pekerjaan dan lingkungan kerja. Penelitian bertujuan mengetahui perbedaan karakteristik dan biomarker paparan lingkungan kerja seperti: MT1a, GSTp1 dan PSA antara pekerja bengkel las dan pekerja kantor administrasi. Desain penelitian yang digunakan adalah cross sectional. Subyek penelitian adalah 30 orang pekerja bengkel las dan 30 orang pekerja kantor administrasi yang diambil secara purposive sampling. Variabel yang diteliti adalah factor pekerja berupa usia dan IMT, kadar enzim GSTp1, MT1a dan PSA. Pengukuran GSTp1, MT1a dan PSA dalam darah dilakukan menggunakan metode ELISA sandwich. Analisis data dilakukan dengan uji Mann-Whitney. Hasil penelitian menunjukkan adanya perbedaan signifikan usia, IMT dan kadar PSA pada kedua kelompok, dan tidak ada perbedaan signifikan kadar GSTp1 dan MT1a antara kelompok. Kesimpulannya bahwa kadar PSA kelompok pekerja kantor lebih tinggi dibandingkan kelompok pekerja bengkel las, dimungkinkan karena rerata usia yang lebih tua.
Exercising sheep as a preclinical model for musculoskeletal research
Authors: Vergara-Hernandez Fernando B. , Nielsen Brian D. , Panek Char L. , Robison Cara I. , Colbath Aimee C. 
Published: December 2023

Abstract

OBJECTIVE
To establish an orthopedic, preclinical, ovine model of controlled exercise using an equine walker.

ANIMALS
20 Dorset-Polypay sheep.

PROCEDURES
Sheep underwent 11 weeks of exercise, 4 days per week. Exercise duration and intensity increased until sheep performed 25 minutes at 1.3 m/s and 5 min at 2.0 m/s. Physical/lameness examinations were conducted every 14 days. Blood was collected every 28 days for analysis of serum bone biomarkers (SBB): bone alkaline phosphatase (BALP), procollagen type I amino-terminal propeptide (PINP), carboxy-telopeptide of type I collagen cross-links (CTX-I), tartrate-resistant acid phosphatase 5b (TRAP5b), and receptor activator of nuclear factor-kβ ligand (RANKL).

RESULTS
Sheep adapted easily to group exercise. Animals grew taller (P = .006) but had a 4% weight loss (P = .003). RANKL was reduced on days 28 and 84 compared to day 56 (P < .05), CTX-1 was reduced on days 28 and 84 compared to days 0 and 56 (P < .05), and TRAP5b was greater on day 28 compared to day 0 (P = .009). BALP and PINP did not change.

CLINICAL RELEVANCE
The described preclinical model of exercising sheep has distinct advantages including ease of handling, an established lameness scale, commercially available ovine SBB assays, and the ability to alter footing characteristics and complete circular exercise. Decreasing CTX-I and RANKL with no change in BALP and PINP suggests reduced bone resorption over the study period. Future studies may include a sedentary group or utilize adult animals to alleviate any influence of growth on SBB.
What Does a Modern Coach Need to Become a Master in Dialogue with a Player?
Authors: Kuk Anna , Derbich Jolanta 
Published: December 2023

Abstract
The aim of the research was to discover students’ opinions on the characteristics and qualities of a coach that, in their opinion, determine the structure of a relationship based on dialogue in the process of sports training. A diagnostic survey was used for the research by asking the respondents an open-ended question: „What do you expect from a coach who you would consider to be a master in dialogue with an athlete?”. The study involved 103 students of the Józef Piłsudski University of Physical Education in Warsaw studying in the first year of full-time studies, majoring in sport. There were 80 men (77.7%) and 23 women (22.3%) in the study group. The average age of the respondents was 19.3 years. 76.3% of the students surveyed stated that they do sports. An analysis of the students’ statements was conducted in relation to the normative model of the personality of a physical culture specialist (Hodan & Żukowska 1996), which distinguishes three dimensions of this profession: specialist, pedagogue and human being. The analysis of the statements clearly indicates that, in their opinion, in order for a coach to become a master in dialogue with an athlete, he or she must strive to develop his or her competences, which are defined by all three dimensions indicated above.
Understanding the roles of the microbiome in autoimmune rheumatic diseases
Authors: Amarnani Abhimanyu , Silverman Gregg J. 
Published: December 2023

Abstract
The gut microbiome represents a potential promising therapeutic target for autoimmune diseases. This review summarizes the current knowledge on the links between the gut microbiome and several autoimmune rheumatic diseases including rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) spondyloarthropathies (SpA), Sjogren’s syndrome (SS), and systemic sclerosis (SSc). Evidence from studies of RA and SLE patients suggests that alterations in the gut microbiome composition and function contribute to disease development and progression through increased gut permeability, with microbes and microbial metabolites driving an excessive systemic activation of the immune system. Also, there is growing evidence that gut dysbiosis and subsequent immune cell activation may contribute to disease pathogenesis in SpA and SS. For SSc, there are fewer, but these are still informative, reports on alterations in the gut microbiome. In general, the complex interplay between the microbiome and the immune system is still not fully understood. Here we discuss the current knowledge of the link between the gut microbiome and autoimmune rheumatic diseases, highlighting potentially fertile areas for future research and make considerations on the potential benefits of strategies that restore gut microbiome homeostasis.
Identification and functional prediction of long non-coding RNA and mRNA related to connective tissue disease-associated interstitial lung diseases
Authors: Dai Fei , He Yixi , Lei Tianyi , Jiang Yi , Zhang Quanbo , Qing Yufeng 
Published: December 2023

Abstract

Objective
Recently, the role of long non-coding RNA (lncRNA) in rheumatic immune diseases has attracted widespread attention. However, knowledge of lncRNA in connective tissue disease-associated interstitial lung disease (CTD-ILD) is limited. This study explored the expression profile and possible mechanisms of lncRNA and mRNA in peripheral blood mononuclear cells (PBMCs) of CTD-ILD patients, especially systemic sclerosis (SSc)-ILD and rheumatoid arthritis (RA)-ILD.

Methods
LncRNA microarray analysis identified 240 diferentially expressed lncRNAs and 218 diferentially expressed mRNA in the CTD-ILD group and the connective tissue disease without associated interstitial lung disease (CTD-NILD) group. The bioinformatics analysis of diferential genes has identified several important biological processes and signal pathways, including nuclear factor kappa B (NF-kappa B) signaling pathway, interleukin 17 (IL-17) signaling pathway, B cell receptor signaling pathway. Relative expression levels of five diferentially expressed lncRNAs and one mRNA in 120 SSc and RA patients with or without ILD were detected by quantitative reverse-transcription (PCR).

Results
The ENST00000604692 expression level was significantly higher in the ILD than the without interstitial lung disease (NILD) group; T311354 and arginase-1 were significantly higher in SSc than RA group.

Conclusion
These data suggest that the specific profile of lncRNA in PBMCs of CTD-ILD patients and the potential signal pathways related to the pathogenesis of CTD-ILD, which may provide newfound insights for the diagnosis and treatment of CTD-ILD patients.
Implementation and Analysis of a Digital Twin for Propylene Glycol Production: Dynamic Simulation and Process Statistical Control
Authors: Do Rêgo Gabriela Gonçalves Monteiro , Carneiro Francisco Lucas de Lima , Pereira Juliana Rosa Leite Araújo , Pereira Micael , Pereria Neto Antonio Tavernard , Da Silva Júnior Heleno Bispo 
Published: December 2023

Purpose: Development of a dynamic simulation and analysis system for Propylene Glycol production through the hydrolysis of Propylene Oxide, utilizing market-available tools including a Digital Twin developed in the Unisim/Honeywell Simulation integrated to the PI System AVEVA/OSIsoft. This system aims to provide a realistic industrial environment for subsequent analysis and statical quality control.

Theoretical framework: The manufacturing of Propylene Glycol involves complex reactive systems that require precise control and optimization. The integration of advanced simulation tools and statistical control charts, such as Shewhart Control Charts, is pivotal in monitoring and enhancing the quality of the process. This approach addresses the need for efficient process management in the chemical industry.

Method/design/approach: The project employs a decoupled simulation structure, where the reactive system and the statistical control system operate simultaneously, exchanging information through the PI System supervisory software (AVEVA/OSIsoft) and a Python programming environment. The implementation of Shewhart Control Charts within the simulation provides real-time process quality monitoring.

Results and conclusion: The outcomes demonstrate the feasibility of using a combination of software tools for daily industrial event simulation, as well as for training and acclimatizing engineers and operators. The analysis of statistical control charts allows for the detection of special cause variations, offering valuable insights for efficient process intervention, thereby enhancing the quality of both the process and the final product.

Research implications: This study contributes to a deeper understanding of reactive systems in chemical engineering and the effective integration of simulation and statistical process control techniques.

Originality/value: The development of a simulation framework that combines Digital Twin technology with statistical process control for the efficient and reliable production of Propylene Glycol.
Entrepreneurial Possibilities for Women Residing in the Senador Nilo Coelho Irrigation Project
Authors: Guedes Albertina Marília Alves , Lins Neto Ernani Machado de Freitas , De Melo Rosemary Barbosa 
Published: December 2023

Objective: This study’s main objective is to describe the rural contexto of the Senador Nilo Coelho Irrigation Project (PISNC), located in the municipality of Petrolina/PE and to presente entrepreneurial activities that can be deve loped by women who reside in the aforementioned irrigation Project aiming to generate income.

Method: Considering that this study concerns a theoretical review research with a descriptive bias na based on a qualitative approach, scientific articles, course completion works, master’s dissertations, doctoral theses and books related to the topic in question available on SciELO were consulted; Scopus, and Science Direct. Technical na statistical reports provided by research institutions and entities involved in the implementation and management of the aforementioned irrigation Project were also consulted.

Results and conclusion: The results obtained in the study indicate that some of the types of enterprises that can be carried out by women residing in PISNC are: growing vegetables; cultivation of medicinal, spicy, and/or aromatic plants; production of bread, cakes and sweets; among other activities. Finally, it can be concluded that there are diverse possibilities for women residing in PISNC to plan and develop strategies for entrepreneurial activities aimed at generating income for their families and with low-cost initiatives.

Research implications: The research on the development of entrepreneurial activities that can be carried out by women who reside in the Senador Nolo Coelho Irrigation Project concerns a pioneering study in the region that aims to problematize issues related to women with entre pre neurial potential who reside in a rural contexto.

Originality/value: It is hoped that this study can contribute to the social, economic and academic spheres regarding the entrepreneurial potential of women residing in rural areas.
Distribusi asupan makanan padat energi pada mahasiswa kedokteran Universitas Tarumanagara
Authors: Jonathan  , Rumawas Marcella Erwina 
Published: December 2023

Makanan yang memiliki densitas energi tinggi disebut sebagai makanan padat energi, biasanya merupakan makanan dengan kandungan gula dan lemak yang tinggi. Data Badan Pusat Statistik (BPS) mengindikasikan masyarakat Indonesia cenderung mengonsumsi makanan padat energi dalam jumlah besar. Tujuan studi ini ialah untuk mengetahui distribusi asupan makanan padat energi pada mahasiswa Fakultas Kedokteran Universitas Tarumanagara. Studi bersifat deskriptif potong lintang ini meliputi sampel mahasiswa Fakultas Kedokteran Universitas Tarumanagara yang dipilih secara non-random konsekutif dan bersedia ikut serta dalam studi ini. Data pola konsumsi makanan selama 1 bulan terakhir dikumpulkan dengan mengisi kuisioner Semi-Quantitative Food Frequency Questionnaire, selanjutnya diolah dengan Nutrisurvey untuk menghitung densitas energi makanan. Hasil studi pada total 92 responden didapatkan rerata (SD) densitas energi makanan sebesar 143,8 (20,75) kcal/100g. Densitas energi makanan lebih besar didapatkan pada responden dengan kebiasaan merokok dan berolahraga maupun responden tanpa riwayat diabetes atau hipertensi dibandingkan responden dengan keadaan sebaliknya. Distribusi densitas energi makanan pada kelompok makanan pokok dan olahannya tertinggi pada tertil 2, kelompok sayur, buah, dan produk susu tertinggi pada tertil 1, kelompok protein hewani, kacang, jajanan, dan minuman manis tertinggi pada tertil 3. Berdasarkan hasil studi, disarankan mahasiswa kedokteran Universitas Tarumanagara dapat membatasi jumlah konsumsi makanan padat energi.
Gambaran variasi uji kapasitas antioksidan DPPH, FRAP dan ABTS pada ekstrak biji jengkol (Archidenfron sp.)
Authors: Ezra Pasuarja Jeranding , Limanan David , Ferdinal Frans , Yulianti Eny 
Published: December 2023

Antioksidan adalah substansi yang dapat menyumbangkan elektron ke radikal bebas. Antioksidan sintetik dan antioksidan alami adalah dua kategori utama asal antioksidan. Tanaman jengkol (Archidendron sp), misalnya, merupakan sumber antioksidan alami. Keadaan alam, kesuburan tanah, perawatan tanaman, dan spesies semuanya berperan dalam kemampuan antioksidan jengkol. Studi ini berangkat untuk meninjau tiga tes yang biasa digunakan untuk mengukur aktivitas antioksidan, dalam hal ini ekstrak biji jengkol (Archidendron sp) diukur kapasitasnya. Mekanisme kerja dari ketiga metode ini dibedakan berdasarkan pada mekanisme reaksinya dalam mereduksi suatu oksidan. Hasil dari masing masing ujii kapasitas antioksidan ekstrak biji jengkol, pada metode ABTS didapatkan nilai IC50 sebesar 36,389 µg/mL. Pada metode DPPH nilai IC50 yang diperoleh sebesar 174,645 µg/mL. Adapun pada metode FRAP besaran IC50 yang didapatkan yaitu 48,275 µg/mL. Korelasi semua uji antioksidan pada ekstrak dapat dipercaya (R2 > 0,95).
Probability of Inappropriate Complementary Feeding Practices on Children Aged 6-23 Months in Indonesia: Results of Indonesian Demographic Health Survey in 2017
Authors: Demsa Simbolon  , Indah Vita Anggraini  
Published: December 2023

Background: One of the causes of the double burden of nutrition problems in Indonesia is the early feeding of complementary feeding. The practice of providing complementary feeding in several countries, including Indonesia, has not reached the target and it is not yet known the magnitude of the probability of complementary feeding not following the recommendations in Indonesia based on national survey data.
Objective. To identify the risk factors for the failure of Infant and Young Child Feeding (IYCF) practice in urban and rural NTT.
Objectives: This study aims to determine the Probability of inappropriate complementary feeding practices in Children aged 6-23 Months in Indonesia and the factors that influence it.
Methods: The research design uses cross-sectional studies. The data is sourced from the 2017 Indonesian Health Demographic Survey (IDHS) results. The sample was selected from women of childbearing age in IDHS 2017, namely women of childbearing age aged 15-49 years who had children aged 6-23 months who met the inclusion and exclusion criteria of 4,985 children. The data were analysed using multivariate logistic regression.
Results: The practice of giving complementary feeding according to recommendations in children aged 6-23 months in Indonesia is only 55.53%. Socio-economic status is very poor (p= 0.000; OR=1.785; 95% CI 1.44-2.213), rural residence (p= 0.000; OR=1.168; 95% CI 1.025-1.33), lower education (p= 0.002; OR=1.398; 95% CI 1.149-1.702), and grande multipara parity (p= 0.001; OR=1.57; 95% CI 1.238-1.992) is significantly associated with the practice of giving complementary feeding not by the recommendations.
Conclusions: The probability of the practice of giving complementary feeding is not by the recommendation of 86% due to the socio-economic status of very poor families living in rural areas, low maternal education levels, and mothers with grande-multipara parity. It is necessary to improve the socio-economics of the family through the empowerment of mothers and families, increase access to health services in rural areas, improve maternal education through various programs, and intensify family planning programs to limit the number of children in the family.