bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Pelvic Floor Muscle and Education-based Therapies on Bladder, Bowel, Vaginal, Sexual, Psychological Function, Quality of Life, and Pelvic Floor Muscle Function in Females Treated for Breast Cancer: A Systematic Review
Authors: Cyr Marie-Pierre , Jones Tamara , Colombage Udari N. , Frawley Helena C. 
Published: January 2025

Abstract

Purpose of review
Breast malignancy is the most common cancer in females. Symptoms of pelvic floor disorders and sexual dysfunction secondary to systemic cancer treatment may occur. Non-surgical, non-pharmaceutical conservative therapies, namely pelvic floor muscle (PFM) and education-based therapies, could be beneficial to reduce these symptoms in this population. This systematic review aimed to examine the evidence regarding their effectiveness on bladder, bowel, vaginal, sexual, psychological function, quality of life, and PFM function in breast cancer populations.

Recent findings
Six databases were searched to identify interventional studies on the effect of PFM therapies, education-based therapies, or combined (multimodal) therapies on any outcome of interest. The search yielded 603 results, from which 12 studies were included. Of these, six (50%) were RCTs, one (8%) was a non-RCT with two groups, and five (42%) were non-RCTs with a single group. Findings suggest that PFM therapies (active) may be beneficial, and education in the format of CBT may improve bladder function. No data were found for bowel function and results from two RCTs were inconclusive to draw conclusions for vaginal function. Sexual function was the most frequently reported outcome. PFM therapies (active > passive) may be beneficial, and education is more likely than not to improve sexual function. For psychological function, PFM therapies (active + passive) may be beneficial, and education is more unlikely than likely to improve psychological function. For quality of life, PFM therapies (active + passive) may be beneficial, and education is more unlikely than likely to improve quality of life, although CBT combined with physical exercise may provide further improvement. PFM therapies (active ± passive) may improve PFM function. Given the limited number of studies and their methodological limitations, caution should be exercised when interpreting these study results. More research is needed to confirm findings and to investigate the clinical value of PFM therapies and combined, multimodal therapies for breast cancer populations.

Summary
Non-surgical, non-pharmaceutical conservative therapies may be helpful for breast cancer populations. Clinicians should consider the highest level of available evidence to guide their practice and use their clinical judgement to select the treatment components and appropriate dosages.
A turn of tide in the fight against corruption in Romania: the CJEU between systemic risk of impunity and fundamental rights
Authors: Tănăsescu Elena-Simina , Selejan-Guţan Bianca 
Published: January 2025

Abstract
In the last decade, the interaction between the European Court of Justice and the Romanian Constitutional Court followed a sinusoidal pattern: after the direct dialogue initiated by a preliminary question on the freedom of movement for same-sex couples, parallel monologues on the relationship between the national Constitution and EU law have become the rule. This article examines the recent CJEU Case C-107/23 PPU ‘Lin’, which represents a turn of tide in the interaction between the CJEU and the Romanian Constitutional Court, but also a confirmation of the loss of interest of the CJEU in the topic of the fight against corruption in Romania.
Creating a well-functioning internal market for biofuels
Authors: Talus Kim 
Published: January 2025

Abstract
State aid for renewable energy is a crucial element in the transition to a carbon-neutral energy system. However, various State aid schemes in different Member States can also lead to undesirable market distortions and hinder cross-border trade. This is particularly so when one Member State provides production aid, and another Member State has a demand side aid scheme or can result from some Member State providing both State aid and GOs for the same commodity. This undermines the level playing field for all actors within the biomethane markets and leads to subsidy competition, instead of product competition. The article addresses these questions and provides for solutions.
Effects of Tasimelteon Treatment on Traumatic Brain Injury Through NRF-2/HO-1 and RIPK1/RIPK3/MLKL Pathways in Rats
Authors: Özden Eyyüp Sabri , Özcan Mustafa Soner , Savran Mehtap , Ilhan Ilter , Tepebası Muhammet Yusuf , Sevuk Mehmet Abdulkadir , Özmen Özlem 
Published: January 2025

Abstract
Secondary brain damageafter traumatic brain injury (TBI) involves oxidative stress, neuroinflammation, apoptosis, and necroptosis and can be reversed by understanding these molecular pathways. The objective of this study was to examine the impact of tasimelteon (Tasi) administration on brain injury through the nuclear factor erythroid 2-related factor 2 (NRF-2)/heme oxygenase-1 (HO-1) and receptor-interacting protein kinase 1 (RIPK1)/receptor-interacting protein kinase 3 (RIPK3)/mixed lineage kinase domain-like (MLKL) pathways in rats with TBI. Thirty-two male Wistar albino rats weighing 300–350 g were randomly divided into four groups: the control group, trauma group, Tasi-1 group (trauma + 1 mg/kg Tasi intraperitoneally), and Tasi-10 group (trauma + 10 mg/kg Tasi intraperitoneally). At the end of the experimental phase, after sacrifice, blood samples and brain tissue were collected for biochemical, histopathological, immunohistochemical, and genetic analyses. Tasi increased the total antioxidant status and decreased the total oxidant status and oxidative stress index. In addition, Tasi caused histopathological changes characterized by a markedly reduced hemorrhage area in the Tasi-1 group. Normal brain and meningeal structure was observed in rats in the Tasi-10 group. Immunohistochemical analysis indicated that Tasi also decreased the expression of interferon-gamma, caspase-3, and tumor necrosis factor-alpha in the brain tissue. Although NRF-2 and HO-1 expression decreased, RIPK1/RIPK3/MLKL gene expression increased due to trauma. However, Tasi treatment reversed all these findings. Tasi protected against brain injury through the NRF-2/HO-1 and RIPK1/RIPK3/MLKL pathways in rats with TBI.
From Sexting to Sexpreading: Trivialization of Digital Violence, Gender Differences and Collective Responsibilities
Authors: Fernández Laura , Alvarez-Cueva Priscila , Masanet Maria-Jose 
Published: January 2025

Abstract
This article starts from a pedagogical disambiguation around sexting elaborated from the socio-educational cooperatives edPAC and CANDELA. This nuanced definition understands sexting as the practice of voluntarily and consensually sharing intimate and sexual content through different platforms and devices. In contrast, sexpreading is understood as the practice of disseminating sexual content without consent. We conducted short-term ethnographic research with adolescents in Barcelona with the objective of understanding how they perceive sexting and sexpreading based on their own experiences and social context. The research was carried out in three education centers in Barcelona and its metropolitan area and involved 59 diverse young people from 14 to 18 years old with different gender identifications. Our results point to three main dimensions: 1) the trivialization of violence and the creation of men spaces; 2) the gender differences involved in practicing sexting and preventing sexpreading; and 3) the consequences of sexpreading experienced by young people, including roles of intermediaries and responsibilities associated with them. We provide empirical and ethnographical support for the idea that merging sexting and sexpreading is problematic, especially for educational interventions, as it can detrimentally generalize issues and negatively impact adolescent sexualities, in particular those of girls and women. We believe that it is very important to incorporate discussions about sexting and sexpreading practices into educational contexts and to consider the high degree of media skills young women already have for a pedagogy of sexting and a community intervention against sexpreading.
Stair-descent phenotypes in community-dwelling older adults determined using high-level balance tasks
Authors: Tanaka Takahiro , Hase Kimitaka , Mori Kimihiko , Wakida Masanori , Arima Yasuaki , Kubo Takanari , Taguchi Meguru 
Published: January 2025

Abstract

Background
Falls on stairs are a major cause of severe injuries among older adults, with stair descent posing significantly greater risks than ascent. Variations in stair descent phenotypes may reflect differences in physical function and biomechanical stability, and their identification may prevent falls.

Aims
This study aims to classify stair descent phenotypes in older adults and investigate the biomechanical and physical functional differences between these phenotypes using hierarchical cluster analysis.

Methods
Eighty-two older adults participated in this study. Stair descent was measured using a three-dimensional motion analysis system. Physical function was assessed using measures of muscle strength, walking speed, the Timed Up and Go Test (TUG), and the Community Balance and Mobility Scale (CB&M).

Results
Hierarchical cluster analysis was performed on kinematic data obtained during stair descent. Three phenotypes were identified: neutral (N-type; 24%), extension (E-type; 52%), and rotation (R-type; 23%). There were no significant differences in lower limb muscle strength or walking speed among the different types, and TUG scores showed no differences in terms of mobility or balance abilities. However, CB&M scores were significantly lower for E-type and R-type compared to N-type. Sub-analyses revealed that while there were no differences in the mobility factor of CB&M between E-type and R-type, the strength factors were significantly lower compared to those for N-type.

Discussion
These results suggest that E-type and R-type stair-descent patterns may be influenced by declines in standing balance ability and muscle strength.

Conclusions
These findings may inform fall-prevention training programs related to stair descent among older adults.
Real-World Applications of Analytic Travelling Wave Solutions of a (3+1)-Dimensional Hirota–Satsuma–Ito-Like System Via Polynomial Complete Discriminant System and Elementary Integral Technique
Authors: Adeyemo Oke Davies 
Published: January 2025

Abstract
Models reveal the dynamic character of wave motion, delineated in shallow waters alongside fluid dynamics; an example is the Hirota–Satsuma–Ito model equation. Therefore, this paper showcases the detailed analytical investigations of a (3+1)-dimensional Hirota–Satsuma–Ito-like system. In order to reduce the equation to a nonlinear ordinary differential system of equations, a traveling plane wave transformation is engaged. Thereafter, the direct integration technique is adopted to solve the model, thus culminating in obtaining Jacobi elliptic integral function solutions. Moreover, to attain more various solitonic solutions of diverse structures, a standard approach called the polynomial complete discriminant system and elementary integral technique is engaged. This provides exact traveling wave solutions of diverse known functions in the form of periodic, trigonometric, dark, mixed bright, and topological kink, as well as singular soliton solutions. These are found to appear in the form of Jacobi elliptic, trigonometric, as well as hyperbolic functions. Furthermore, some of these solutions are further examined by investigating their wave nature via numerical simulations.
Mesoscopic homogenization method of mechanical properties of fused filament fabrication structures considering void shapes and filament interfaces
Authors: Springmann Marlies , Middendorf Peter 
Published: January 2025

Abstract
The Fused Filament Fabrication process (FFF) is an additive manufacturing process for thermoplastic polymers based on material extrusion. It offers a large range of material options and high potential for manufacturing parts with complex geometry. Mechanical properties of parts produced with this method are, however, highly anisotropic and depend on process parameters and resulting inner mesostructures. The relationships between process parameters, mesostructures and mechanical properties are complex. Characteristics of the FFF mesostructures, such as voids and the interfaces between filaments, cannot yet be sufficiently taken into account in macroscopic design methods. In this work, a method for homogenising mechanical properties is developed. This is based on the inner FFF mesostructure: shape and size of the voids are determined using micrographs and the size of the coalescence areas between the filaments is also estimated. Representative volume elements with periodic boundary conditions are then created in a finite element environment and homogenised mechanical properties are derived. These are compared with analytical and experimental values, and the results are discussed. The method presented here provides an approach on how different characteristics of FFF mesostructures can be transferred to macroscopic simulations. Results of the numerical approach are in good agreement with the experimental data.
Comparative assessment of pollutant emissions between biofuel briquettes and charcoal: implications for domestic cooking fuel selection
Authors: Nganko Junior Maimou , Koffi Ekoun Paul Magloire , Toure Alpha Ousmane , Gbaha Prosper , Tiogue Claudine Tekounegning , Ndiaye Babacar , Ba Kalidou , Benjamin Yao Kouassi 
Published: January 2025

Abstract
Fuels influence indoor air quality and occupants' health. This study aims to evaluate and compare the emissions of carbon monoxide (CO), carbon dioxide (CO2), and aerodynamic size less than or equal to 2.5 µm (PM2.5) from biofuel briquettes to those from household charcoal. This approach allows for selecting a fuel based on its pollutant emissions. CO emissions ranged between 0.79 ± 0.014 and 7.430 ± 0.063 g/MJ delivered for biofuels and charcoal, respectively. The emitted CO2 ranged between 2 ± 0.212 and 129 ± 1.41 g/MJ delivered for biofuels and charcoal, respectively. The PM2.5 emissions from biofuels and charcoal were 507.5 ± 61.5 and 256.50 ± 13.44 mg/MJ delivered, respectively. The specific fuel consumption varied between 4.16 ± 0.056 and 1.35 ± 0.120 kg/L for biofuels and charcoal, respectively. The Bravais-Pearson statistical tests revealed a strong correlation between pollutant emissions and certain fuel properties. The analysis of variance (ANOVA) revealed a significance in the data, with a p-value of 0.05. The results obtained provide scientific evidence to support the promotion of biofuels for cleaner, affordable, and sustainable energy from sawdust, aiming to reduce deforestation.

Graphical Abstract
Scientific Definitions and Measurements of Second-Growth, Mature, and Old-Growth Forests
Authors: Frye Ethan A. , Copenheaver Carolyn A. , Gallagher Ann M. , Wiseman P. Eric 
Published: January 2025

Abstract
We examined US scientists’ (1) use of second-growth, mature, and old-growth forest in scientific publication titles, (2) definitions of second-growth, mature, and old-growth forest, and (3) sampling methods in second-growth, mature, and old-growth forest. “Second-growth forest” (55 titles) and “mature forest” (40) experienced the most frequent use in the 2010s. “Old-growth forest” (247) had the most use in the 1990s. Definitions of second-growth forest originated from successional theory and were consistent across scientists. Definitions of mature forest lacked consensus. Definitions of old-growth forest increased in complexity as scientists integrated biological, social, and political factors. Soil was the most frequent abiotic factor measured in mature and old-growth forests. In second-growth forests it was dead organic matter. Trees were the most common life form measured in all forests. The results show that researchers would benefit from a clearer differentiation between second-growth and mature forest and a formal definition for mature forest.
Twenty-Two-Year Study of the Spread and Impact of Hemlock Woody Adelgid and Elongate Hemlock Scale in Southwest Virginia
Authors: McAvoy Thomas J. , Mays Ryan , Salem Mohamed , Chamberlin Lori , Rhea Rusty , Asaro Christopher , Salom Scott M. 
Published: January 2025

Abstract
This 22-year study examined the impact and dispersal of the hemlock woolly adelgid (HWA) and the elongate hemlock scale at 67 sites in southwest Virginia. A hemlock stand health index was based on percent foliage density, live crown ratio, live branches, live tips, new foliage, and live trees at each site. At the beginning of the study, hemlock health at all sites was good. After 22 years hemlock health had declined to a poor condition and mortality averaged 30%. Differences in health decline were found among the three physiographic mountain regions. Analysis of the variables measured indicated that hemlock stand health decline was positively correlated with the percentage of branches infested with HWA, hemlock diameter at breast height (dbh), and total tree basal area per hectare and negatively correlated with latitude. Crown density, the inverse of Forest Inventory and Analysis (FIA) canopy foliage transparency could be used as a standalone hemlock health measurement.
Loblolly pine growth and competition response to varied chemical site preparation and release treatments 14 years after establishment in the Piedmont of Virginia
Authors: Byers Alexander , Carter David R. , Cook Rachel L. , Strahm Brian , Creighton Jerre 
Published: January 2025

Abstract
We examined the 14-year effects of experimentally varied chemical site preparation and release treatments in a Pinus taeda L. plantation in Dillwyn, Virginia, US. The study examined the effects of timing (July, September, or October) for imazapyr site preparation, with or without the addition of sulfometuron methyl (SFM), year-one release from herbaceous weeds using SFM plus imazapyr, and year-two release treatment using imazapyr at a rate to control hardwoods. Chemical site preparation treatment applications exhibited a reduction in competition basal area ha-1 and an increase in pine volume compared to the check, however, application timing was the most influential factor in determining the effectiveness of the treatments. September 3rd and October 1st applications averaged less competing vegetation basal area than the year-two release and the check plots. At age 14-years, competing vegetation reduced individual pine tree volumes by 5.6% for every one m2 of competing vegetation basal area.
Risk Factors for Hydrocephalus After Decompressive Craniectomy
Authors: Knorovsky Kamil , Katuch Vladimir , Banoci Jan , Grega Rastislav , Magocova Veronika , Sabo Vladimir , Orlicky Michal , Gajdos Miroslav , Kolarcik Peter 
Published: January 2025

Abstract

Background
Decompressive craniectomy is a life-saving neurosurgical procedure that is performed to interrupt the pathophysiological processes associated with intracranial hypertension. This retrospective study aims to identify risk factors related to the development of hydrocephalus after decompressive craniectomy.

Methods
We retrospectively analyzed the data of 184 patients who underwent decompressive craniectomy between January 1, 2018, and December 31, 2022. The analysis included various risk factors, including initial diagnostic parameters, technical aspects of the operation, and postoperative complications.

Results
From the analysis, we found that the incidence of subdural hygroma, blood contamination of the ventricular system, and postoperative infectious complications are associated with an increased risk of developing hydrocephalus. At the same time, we found that some technical parameters of the operation, such as the size of the decompressive craniectomy, do not significantly affect the development of hydrocephalus.

Conclusions
Identification of risk factors associated with the development of hydrocephalus after decompressive craniectomy helps intensively monitor such patients. The result is a reduction in the incidence of hydrocephalus and better management of its eventual occurrence.
Could Urinary Amino Acids be as New Biomarkers for Detection of Sarcopenia?
Authors: Sivritepe Rıdvan , Basat Sema Uçak , Gökmen Neslihan , Duygu Aydın , Siyer Özge Kıran , Tiril Serhat Mert 
Published: January 2025

Abstract

Background
Sarcopenia is a syndrome that cause falls, fractures, and morbidity in geriatric patients. Early diagnosis of sarcopenia is important as it is known that muscle functions can improve with early intervention. We aimed to investigate whether urinary amino acid levels could serve as biomarkers of sarcopenia.

Methods
The study included ninety-one patients aged 45–65 who visited to our outpatient clinic. The patients underwent physical examinations, blood tests and sixteen distinct urinary amino acid levels were analyzed. Anthropometric measurements were performed. Physical performances were evaluated. Muscle strengths were measured. Muscle masses were analyzed. Patients were divided into 4 groups: pre-sarcopenic, sarcopenic, severe sarcopenic and non-sarcopenic. Statistical significance level was determined as p < 0.05.

Results
A total of ninety-one patients, 53 females and 38 males, were included in the study. Three patients had pre-sarcopenia, eleven had sarcopenia, and two met the criteria for severe sarcopenia, while seventy-five patients were non sarcopenic. A significant difference was found between the sarcopenia and non-sarcopenia groups in terms of glutamine and valine levels (p < 0.001 for both). In the ROC analysis, the cut-off value of glutamine and valine levels in detecting sarcopenia was determined as 492 µmol/L and 209 µmol/L (AUC: 0.875 and 0.968). Correlation analysis revealed a negative relationship between urinary leucine levels and both muscle strength and muscle mass

Conclusions
We found that patients with sarcopenia had high urinary glutamine and valine levels and that urinary leucine levels were associated with both muscle strength and muscle mass.
SINFONIA AND BERIO'S PIONEERING POETICS
Authors: Crayton Stephane 
Published: January 2025

AbstractLuciano Berio's name appears once in the 1,134-page Oxford Handbook of Western Music and Philosophy (2021), yet his poetics sits among the most profound and expansive of the twentieth century. By the mid-1960s Berio was writing lucidly about tensions between synchronic and diachronic meaning. Such works as Sinfonia, the Sequenze and the electroacoustic output are radical applications of these ideas, yet they have been claimed by the proponents of the very structures they challenge and their meanings effectively reduced, notwithstanding Berio's insistence and clarity across his substantial writings. This article characterises Berio's work according to his poetics, demonstrating the ways in which Sinfonia actively stages the mechanisms of musical meaning, before situating Berio's writing in a context of contemporary theories of meaning. Particular comparison is made to the work of Harold Bloom, whose words transformed poetic discourse in the 1970s.