bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of visual fidelity on screen-based virtual reality food choices: A randomized pilot study
Authors: Curi Braga Bianca , Sajjadi Pejman , Bagher Mahda , Klippel Alexander , Menold Jessica , Masterson Travis 
Published: January 2025

Objective
To understand the impact of fidelity and perceived realism on virtual reality food choices, and task motivation, engagement, and interest.

Design
Randomized controlled trial.

Setting
Online.

Participants
84 participants recruited from Amazon Mechanical Turk.

Intervention
Participants were randomly assigned to either a high- (n = 43) or a low- (n = 41) visual fidelity environment and were asked to select foods to have a meal with a friend.

Main outcome measures
Food choice, motivation of food choices, engagement, and interest.

Analysis
Simple linear regressions between visual fidelity and perceived realism, and log-linear regressions for visual fidelity or perceived realism on either motivation, interest, or engagement. Poisson models between visual fidelity or perceived realism, and food selections.

Results
Manipulating visual fidelity was not associated with perceived realism, motivation, interest, or engagement in the food selection task. Perceived realism increased motivation by 0.3% (SE 0.056; p = 0.022), interest by 1.4% (SE 0.002; p<0.001), and engagement by 0.9% (SE 0.001; p<0.001) in the food selection task. High visual fidelity decreased the total number of foods selected (B = 0.216; CI (-0.384; -0.047); p = 0.012).

Conclusion and implications
Perceived realism, but not visual fidelity, is important for task related factors like motivation, engagement, and interest. Visual fidelity may influence some food selections.
Computational analysis of the effect of a binding protein (RbpA) on the dynamics of Mycobacterium tuberculosis RNA polymerase assembly
Authors: Bheemireddy Sneha , Sowdhamini Ramanathan , Srinivasan Narayanaswamy 
Published: January 2025

Background
RNA polymerase-binding protein A (RbpA) is an actinomycetes-specific protein crucial for the growth and survival of the pathogen Mycobacterium tuberculosis. Its role is essential and influences the transcription and antibiotic responses. However, the regulatory mechanisms underlying RbpA-mediated transcription remain unknown. In this study, we employed various computational techniques to investigate the role of RbpA in the formation and dynamics of the RNA polymerase complex.

Results
Our analysis reveals significant structural rearrangements in RNA polymerase happen upon interaction with RbpA. Hotspot residues, crucial amino acids in the RbpA-mediated transcriptional regulation, were identified through our examination. The study elucidates the dynamic behavior within the complex, providing insights into the flexibility and functional dynamics of the RbpA-RNA polymerase interaction. Notably, potential allosteric mechanisms, involving the interface of subunits α1 and α2 were uncovered, shedding light on how RbpA modulates transcriptional activity.

Conclusions
Finally, potential ligands meant for the α1–α2 binding site were identified through virtual screening. The outcomes of our computational study serve as a foundation for experimental investigations into inhibitors targeting the RbpA-regulated dynamics in RNA polymerase. Overall, this research contributes valuable information for understanding the intricate regulatory networks of RbpA in the context of transcription and suggests potential avenues for the development of RbpA-targeted therapeutics.
Predicting the risk of bone metastases in patients with newly diagnosed prostate cancer – Development and validation of a nomogram model
Authors: Xu Wei , Zhu Guoyu , Wang Xiaoxiang , Yan Xuebing , Wang Fujun , Li Shanyi , Li Wenji 
Published: January 2025

Objectives
The aim of this study was to develop and validate a nomogram model that predicts the risk of bone metastasis (BM) in a prostate cancer (PCa) population.

Methods
We retrospectively collected and analyzed the clinical data of patients with pathologic diagnosis of PCa from January 1, 2013 to December 31, 2022 in two hospitals in Yangzhou, China. Patients from the Affiliated Hospital of Yangzhou University were divided into a training set and patients from the Affiliated Clinical College of Traditional Chinese Medicine of Yangzhou University were divided into a validation set. Chi-square test, independent sample t-test, and logistic regression were used to screen key risk factors. Receiver operating characteristic (ROC) curves, c-index, calibration curves, and decision curves analysis (DCA) were used for the validation, calibration, clinical benefit assessment, and external validation of nomogram models.

Results
A total of 204 cases were collected from the Affiliated Hospital of Yangzhou University, including 64 cases diagnosed as PCa BM and 50 cases collected from the Affiliated Clinical College of Traditional Chinese Medicine of Yangzhou University, including 12 cases diagnosed as PCa BM. Results showed that history of alcohol consumption, prostate stiffness on Digital rectal examination(DRE), prostate nodules on DRE, FIB, ALP, cTx, and Gleason score were high-risk factors for BM in PCa and nomogram was established. The c-index of the final model was 0.937 (95% CI: 0.899–0.975). And the model was validated by external validation set (c-index: 0.929). The ROC curves and calibration curves showed that the nomogram had good predictive accuracy, and DCA showed that the nomogram had good clinical applicability.

Conclusions
Our study identified seven high-risk factors for BM in PCa and these factors would provide a theoretical basis for early clinical prevention of PCa BM.
Prevalence and associated factors of diabetes among adult populations of Hawassa town, southern Ethiopia: A community based cross-sectional study
Authors: Belete Getu Kassa , Sithole Hlupheka Lawrence 
Published: January 2025

Introduction
Knowing the magnitude and preventable risk factors of diabetes has a significant contribution in targeted prevention intervention which ultimately ensures the existence of healthier and productive individuals in a country. Diabetes has untoward impact on health, social and economic consequences. Exploring preventable risk factors are extremely important because of their potential association and interaction with diabetes. Therefore, the aim of this study was to investigate the magnitude and modifiable risk factors of diabetes among adult populations in Hawassa town, southern Ethiopia.

Methods
A community based cross-sectional study was conducted from September, 2023 to November, 2023 among adult populations. A multi-stage sampling technique was employed to select 1,113 study participants between the ages of 20–69 years. An interviewer-administered questionnaire was used to collect data. Additionally, participants were also instructed to fast overnight, after which the standard fasting blood glucose test was conducted. A binary logistic regression model was fitted to identify independent predictors of diabetes.

Results
The overall prevalence of diabetes was 14.4% (95% Confidence Interval (CI): 12.4%, 16.4%). Being male (Adjusted Odds Ratio (AOR):2.10; 95% CI: 1.34, 3.29), being unable to read and write (AOR: 3.38; 95% CI: 1.09, 10.47), read and write (AOR: 3.38; 95% CI: 1.09, 10.47) and medium cycle (AOR 2.79; 95% CI: 1.02, 7.63) compared to college and above, consume less than 5 servings of fruits on daily base (AOR: 2.80; 95% CI: 1.18, 6.62), having ever chewed khat (AOR 6.50; 95% CI: 4.07, 10.39) and being overweight and obese (AOR: 2.43; 95% CI: 1.54, 3.83) were independently associated with diabetes mellitus (DM).

Conclusion
This study identified a high prevalence of diabetes among adults in Hawassa, driven by various risk factors. This presents an opportunity to mitigate diabetes risk through public health measures, including avoiding khat chewing, promoting healthy diets, managing overweight and obesity, implementing community-based screening, enhancing health literacy, and integrating health information into daily life.
The physical activity and sedentary behavior among pregnant women in Macao: A cross-sectional study
Authors: Mok Ka Chon , Liu Ming , Wang Xin 
Published: January 2025

Objective
The current investigation sought to elucidate the prevalence and contributing factors of sedentary behavior among pregnant women in Macao, a densely populated region characterized by a distinctive fusion of Eastern and Western cultures and a thriving global economy.

Methods
Through a cross-sectional study design, a total of 306 expectant mothers were recruited via various social media platforms and completed a sociodemographic questionnaire alongside the Chinese version of the Pregnancy Physical Activity Questionnaire.

Results
The findings revealed that sedentary activities accounted for a relatively small proportion (7.8%) of the participants’ total activity energy expenditure. Interestingly, employment status emerged as a significant determinant, with employed pregnant women exhibiting a 57.9% lower risk of being sedentary compared to their unemployed counterparts. Moreover, multiparous women (those with two or more children) were approximately 9 times more likely to meet moderate-intensity activity standards than nulliparous women.

Conclusion
These insights highlight the importance of tailoring physical activity interventions to address the specific needs and challenges faced by primiparous women and those who are unemployed during pregnancy, with a view to enhancing education on the potential hazards associated with sedentary habits and promoting active lifestyles within this unique sociocultural context.
Construction on training course and training quality evaluation index system of chronic disease medication therapy management service (MTMs) in China: A Delphi study
Authors: Cai Wenting , Yao Yao , Lei Wenpu , Li Huixin , Yan Simin , Wu Qiuhui , Wang Jian , Ge Weihong , Zhang Jinping 
Published: January 2025

Objective
This study aims to construct a training course and quality evaluation index system for chronic disease Medication Therapy Management service (MTMs) that is suitable for China’s national conditions. It seeks to provide tools and a scientific foundation for assessing the quality of MTMs training.

Methods
Drawing from domestic and international literature and combining with the practice of chronic disease medication management by Chinese pharmacists, a preliminary framework for the evaluation index system was established. The Delphi method was used to solicit expert opinions, evaluate and improve the evaluation index system. Indicator weights were determined by using the Analytic Hierarchy Process (AHP).

Results
Both rounds of expert inquiry achieved a positive degree of 100% (18/18 experts). The authority coefficients (Cr) were 0.90 and 0.91 respectively. The Kendall coordination coefficients (Kendall’s W) of the second and third-level indicators for the first round of inquiry were 0.230 and 0.189, while those for the second round were 0.326 and 0.213. Finally, an MTMs training course and training quality evaluation index system was structured, comprising 3 first-level indicators, 11 second-level indicators, and 39 third-level indicators.

Conclusion
The evaluation index system constructed in this study is scientifically robust and rational, offering a foundation to standardize MTMs training practices effectively.
Voicing experiences of language surveillance to challenge social inequality
Authors: Martín Rojo Luisa , Moustaoui Adil , Ortega Ane 
Published: January 2025

Abstract
While the role of language in inequality is often acknowledged, much remains unknown about how language-mediated inequality occurs. This paper seeks to move the field forward by developing a comprehensive approach to language inequality. The multi-site EquiLing project applied participatory action research (PAR) from a Freirian perspective, focusing on the Madrid region and the Basque Country. In both settings, researchers and participants co-constructed spaces to express and analyze experiences of language inequality. Participants reported the repeated exercise of a power technique – language surveillance – which operated on specific language features of the speakers. Participants’ accounts of their experiences together with shared analyses brought to light, in the first place, the pervasive, ubiquitous, and all-encompassing nature of language surveillance – the continuous observation and assessment of language practices and repertoires that permeate people’s behaviours, bodies, and minds. The article focuses, therefore, on how surveillance, a technique of power, is exercised not only by institutions and their representatives, but also in a myriad of everyday encounters. Secondly, this article highlights the importance of often implicit “speakerhood models” in the exercise of surveillance and, consequently, in the construction of language-based inequality. The research participants’ analysis reveals how speakers who conform to these speakerhood models perceive their social position as superior and authorized to impose negative sanctions on speakers with diverse and multilingual repertoires who deviate from these models. At the same time, speakers subjected to surveillance often contribute it, by internalizing norms and spekearhood models, and performing self-evaluation, that subalternize them. Furthermore, the connection of these models to cultural and linguistic citizenship has a direct impact on community membership and access to resources. Thus, these models perpetuate inequality by constraining participants’ access to social domains, recognition, and active social participation. Finally, this article reflects on how we addressed the challenges of participatory and transformative research. We navigated institutional constraints and hierarchical dynamics by creating spaces of conscientization, fostering collaborative knowledge building, and encouraging participants to critically reflect on their experiences through narrative accounts. In addition, we employed a process of accompaniment to support participants as agents of change in addressing linguistic injustices. These procedures laid the groundwork for the transformative goals of the research.
Development of bone mineral density and content in children with cerebral palsy: a retrospective, longitudinal study
Authors: Koebke Philipp , Schafmeyer Leonie , Lentzen Bruno , Keller Titus , Schoenau Eckhard , Duran Ibrahim 
Published: January 2025

Abstract

Objectives
The aim of this study was to investigate long-term bone development in children with cerebral palsy (CP) using longitudinal measurements of total body less head bone mineral content (TBLH-BMC) and bone mineral density (TBLH-BMD).

Methods
A retrospective longitudinal analysis was performed on 109 children with CP who participated in a rehabilitation programme from 2006 to 2018. Dual-energy X-ray absorptiometry (DXA) scans were performed at the beginning of the programme and repeated as clinically indicated. The study used SITAR growth curve analysis and the LMS method within the GAMLSS model to generate developmental trajectories for TBLH-BMC and TBLH-BMD.

Results
The findings suggest that the expected developmental trajectories of TBLH-BMC and TBLH-BMD in children with CP approximately follow the third percentile of healthy children. The median annual increase in bone mineral density was similar between GMFCS I-II and III-V groups at 5.12 and 5.79 %, respectively. Girls with CP reached age at peak velocity (APV) earlier than boys. The intensive exercise programme may have contributed to greater annual bone growth in children with more severe CP.

Conclusions
Children with CP have bone growth trajectories close to the third percentile of their healthy peers, suggesting that age-adjusted z-scores for TBLH-BMC and BMD remain relatively stable throughout childhood and adolescence. Early and targeted interventions, including improving muscle strength and mobility and optimising nutritional and hormonal status, are essential to promote better bone health and quality of life in children with CP.
Making Sense of Simultaneity: A Reply to Wahlberg
Authors: Silva Caio Cézar 
Published: January 2025

Abstract
In this paper I object some of the criticisms Wahlberg (2017. “Meso-Level Objects, Powers, and Simultaneous Causation.” Metaphysica 18 (1): 107–25) wages against Mumford and Anjum's (2011. Getting Causes from Powers. Oxford: Oxford University Press) account of simultaneous causation. A brief outlook on Wahlberg’s argument in favour of sequential causation is introduced. A first objection is presented and it is shown that sequential causation cannot deal with one of Mumford and Anjum’s argument: the possibility of prevention. When sequential and simultaneous causation are put side by side and how the causal process in each of them interact with a subtractive preventer is analysed, sequential causation becomes visibly flawed while simultaneous causation accommodates the prevention. Then, a second objection argues that the solution Wahlberg puts forward is defective and the time intervals marking the beginning of the cause or effect merely change where the problem appears. Finally, I retort a series of concerns Wahlberg stresses about the structure of simultaneous causation: temporal directedness, causal configuration and non-negligible change and time.
Enhancing Employee Performance Using Workgroup Effectiveness: Role of Member Trust
Authors: Wanuri  , Khayatun Siti , Hartarini Yovita Mumpuni 
Published: January 2025

Research aims to offer comprehensive understanding of the factors influencing organizational performance, particularly in the context of member trust, thereby contributing to broader discourse on human capital management and cooperative development. Utilizing multidimensional framework of human capital and grounded in prevailing challenges faced by cooperative businesses, research elucidates pivotal role of human capital as organizational performance. Approach research was based on descriptive research techniques, in cross-sectional survey, is to observe (collect data about) specific occurrence, often at single point in time. To address research questions, this study adopts descriptive research technique and survey measures to capture objective and social reality of employee performance. Sample included 140 respondents of Flower Market Traders Association in Kopeng, Semarang district, Central Java Province. Data gathering period lasted from January until October 2023. Researcher created questionnaire and collected data using Google Forms. Data analysis was conducted using Structural Equation Modeling (SEM) with Smart-PLS (Partial Least Square) software. Based on study's results, workgroup effectiveness directly influences employee performance and contributes to its success. Moreover, member trust as moderator in correlation between workgroup effectiveness and employee performance. Research offers theoretical and practical implications for implementing workgroup effectiveness to enhance employee performance and member trust as moderator.
СТАНОВЛЕНИЕ ИНСТИТУТА ТОЧНОЙ МЕХАНИКИ И ВЫЧИСЛИТЕЛЬНОЙ ТЕХНИКИ АН СССР В КОНТЕКСТЕ КАМПАНИИ ПО БОРЬБЕ С КОСМОПОЛИТИЗМОМ (1948-1953 ГГ.)
Authors: КРАЙНЕВА И.А. 
Published: January 2025

В статье рассмотрены малоизвестные страницы истории Института точной механики и вычислительной техники АН СССР (ИТМиВТ, Москва) - будущего советского флагмана по созданию ЭВМ - в первые годы его организации и деятельности (1948-1953). На персональном уровне затронут процесс назначения академика М.А. Лаврентьева директором ИТМиВТ, на институциональном - анализируются события, связанные с политико-идеологической кампанией по борьбе с космополитизмом, а также с «засорением кадров» этого академического института специалистами, «не внушающими политического доверия». Роль политических и идеологических кампаний в жизни научно-исследовательских институтов и отдельных ученых не раз становилась предметом исследования. Влияние антикосмополитической кампании на формирование коллектива и деятельность Института точной механики и вычислительной техники АН СССР рассмотрено впервые. Отмечено, что разработчики ЭВМ из ИТМиВТ столкнулись с жесткой конкуренцией со стороны Министерства машиностроения и приборостроения СССР, что привело к задержке выпуска ЭВМ БЭСМ. В исследовании использованы ранее неизвестные документы из Архива Российской академии наук, Российского государственного архива новейшей истории и Российского государственного архива социально-политической истории.
The article considers little known pages in the history of Institute of Precision Mechanics and Computer Engineering of the Academy of Sciences of the USSR (IPMCE, Moscow) - the future Soviet leader in creation of electronic computing machines (ECM), during the first years of its organization and activities (1948-1953). At the personal level, it addresses the process of appointing Academician M.A. Lavrentyev Director of IPMCE. At the institutional level it analyzes events associated with the political and ideological anti-cosmopolitan campaign, as well as measures against “contaminating the personnel” of this academic institution with people lacking political credibility. The role of political and ideological campaigns in the life of research institutions and individual scientists has been recurrently chosen as a subject of study. However, for the first time in historiography the author analyzes the ideological campaign impact on the team building and activities of the Institute of Precision Mechanics and Computer Engineering of the Academy of Sciences of the USSR. At the same time the creators of ECM from IPMCE faced a tough competition from the Ministry of Machine Building and Instrument Engineering of the USSR, which led to the delay in production of ECM BESM. The research is based on the previously unknown documents from the Archive of the Russian Academy of Sciences, the Russian State Archive of the Contemporary History and the Russian State Archive of Socio-Political History.
ОЦЕНКА ЭЛЕМЕНТОВ ВОДНОГО БАЛАНСА ОЗЕРА НИВАЛЬНО-ГЛЯЦИАЛЬНОЙ ЗОНЫ АЛТАЯ
Authors: ПРЯХИНА Г.В. , РАСПУТИНА В.А. , ЗЕЛЕПУКИНА Е.С. , ЗЫРЯНОВА Д.С. , БАНЦЕВ Д.В. , СЫРОМЯТИНА М.В. 
Published: January 2025

Расчет водного баланса для водоемов, находящихся в горах, сложен ввиду недостаточности данных наблюдений и слабой изученности ряда процессов стокоформирования. Гидрологический режим высокогорных озер определяется, с одной стороны, климатическими факторами, а с другой - особенностями подстилающей поверхности водосборных бассейнов с различным соотношением ледниковых и неледниковых частей. В статье на основе данных полевых гидрологических, метеорологических и гляциологических наблюдений выполнен расчет водного баланса с суточным шагом для перигляциального озера, расположенного на территории Южно-Чуйского хребта (Центральный Алтай). Выполненный расчет позволил оценить вклад объемов талых ледниковых вод, таяния снежников и осадков в суммарный приток воды к водоему и выявить особенности поступления талых ледниковых вод в чашу озера. Выявлена преобладающая роль подповерхностного стока в приходной части водного баланса озера.
Calculating the water balance for lakes in the mountains is difficult due to insufficient observation data and poor knowledge of a number of runoff formation processes. The hydrological regime of high-mountain lakes is determined, on the one hand, by climatic factors, and on the other hand, by the characteristics of the underlying surface of catchments with different ratios of glacial and non-glacial parts. In this article, based on data from field hydrological, meteorological, and glaciological observations, the water balance was calculated with a daily step for a periglacial lake located in the Southern Chuya Ridge (Central Altai). Calculating the water balance made it possible to estimate the contribution of meltwater from glaciers and snowfields and of precipitation to the total inflow of water to the lake and to identify the features of the meltwater inflow from glaciers into the lake. The predominant role of subsurface runoff in the incoming part of the lake water balance has been revealed.