bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of health belief model-based training and social support on the physical activity of overweight middle-aged women: a randomized controlled trial
Authors: Faghih Masoumeh , Kaveh Mohammad Hossein , Nazari Mahin , Khademi Khadijeh , Hasanzadeh Jafar 
Published: January 2024

IntroductionThe highest incidence of overweight among adults is found among women, predominantly middle-aged women. While it has been demonstrated that being overweight increases mortality by compromising physical and mental health, it also imposes substantial costs on the healthcare system. Lack of physical activity is a primary contributing factor to becoming overweight. The majority of inactive adults are women, particularly middle-aged women. Consequently, this study investigated the training program for overweight women based on the health belief model (HBM) and social support approach.MethodsA randomized, controlled trial involving 73 overweight middle-aged women (control group: 37, intervention group: 36) was conducted using simple random sampling. The intervention group participated in six 120-min sessions per week for 6 weeks of a training program based on HBM and social support through physical activity, group discussion, role play, and media. Data were collected using the Physical Activity Questionnaire (IPAQ), Bandura’s Exercise Self-Efficacy Scale (Bandura’s ESE), and a researcher-made questionnaire before and 4 weeks after the training. The collected data were analyzed using descriptive and inferential statistics via SPSS 27 software. p-values &lt;0.05 were considered statistically significant.ResultsA training program based on HBM and social support led to improved perceived benefits (p &lt; 0.001), cues to action (p = 0.03), and self-efficacy (p &lt; 0.001) of physical activity; decreased perceived barriers (p = 0.001); increased social support (p = 0.001); and increased physical activity (p &lt; 0.001). In addition, the BMI of the intervention group decreased after the training program (p = 0.01).ConclusionThe findings of the study demonstrate the efficacy of the training program based on HBM and the social support approach in improving social support and physical activity of women. In addition, the study evaluates the long-term outcome in populations with varying social, economic, and cultural standings.Clinical Trials Registrationhttps://clinicaltrials.gov/, (IRCT201706236261N17).
The role of the Field Epidemiology Training Program in the public health emergency response: Sudan armed conflict 2023
Authors: Khairy Amna , Bashier Haitham , Nuh Hatim , Ahmed Nagla , Ali Yousif , Izzoddeen Ahmad , Mohamed Sara , Osman Muntasir , Khader Yousef 
Published: January 2024

BackgroundOn April 15, 2023, the armed conflict between the Sudanese Armed Forces (SAF) and the Rapid Support Forces (RSF) started in Khartoum state, Sudan. This conflict was complicated by the preexisting complicated epidemiological situation and fragile health system in Sudan. This study endeavors to illuminate the pivotal role essayed by the Sudan FETP (SFETP) in enhancing the nation’s public health response, particularly amidst the tumultuous backdrop of armed conflicts that have left their indelible mark on the region.MethodsEmploying a blend of quantitative and qualitative methodologies, we investigated the SFETP’s contributions to the public health response during the initial 4 months of the conflict (April–July 2023). Sixty-four SFETP residents and graduates were invited to participate, and data were gathered through semi-structured questionnaires.ResultsA total of 44 (69%) SFETP residents and graduates were included in this study. Out of 38 SFETPs present in the states, 32 have considerably contributed to the crisis response at state and locality levels. Three-quarters of them have played key leadership, planning, and management roles. In essence, 38% (n = 12) of them have contributed to public health surveillance, particularly in data management, reports, Early Warning Alert and Response System (EWAR) establishment, and epidemic investigation. SFETPs have made special contributions to crisis response at the community level. The involved SFETPs supported WASH interventions (n = 4), and almost one-third of them strengthened risk communication and community engagement (n = 9). Despite their physical presence at the subnational level, 27% of graduates were not deployed to the crisis emergency response. Notably, throughout this time, half of the total SFETPs were formally retained during this response.ConclusionThe study highlighted the importance of FETP engagement and support during public health crises. SFETP residents and graduates played diverse roles in the various levels of public health emergency response to the crisis. However. Strategies to improve the deployment and retention of FETP residents are necessary to ensure their availability during crises. Overall, FETP has proven to be an asset in public health crisis management in Sudan.
Flourishing-Life-Of-Wish Virtual Reality Relaxation Therapy (FLOW-VRT-Relaxation) outperforms traditional relaxation therapy in palliative care: results from a randomized controlled trial
Authors: Woo Olive K. L. , Lee Antoinette M. , Ng Royce , Eckhoff Daniel , Lo Raymond , Cassinelli Alvaro 
Published: January 2024

Introduction: As the global population continues to age, the demand for palliative care is progressively increasing. This growing trend highlights the pressing need for groundbreaking interventions that can effectively manage palliative symptoms and improve the quality of end-of-life care. We present a brief, structured, personalized, and innovative psychological intervention named Flourishing-Life-Of-Wish Virtual Reality Therapy (FLOW-VRT)®, which capitalizes on the distinctiveness of virtual reality (VR) as an advanced technology for symptom management. FLOW-VRT is theoretically based on self-determination theory, stress coping theory, flow theory, and attention restoration theory. With a special focus on relaxation, “FLOW-VRT-Relaxation” is designed to enhance end-of-life coping through personalized VR relaxation. As most studies on the use of VR in palliative care have been feasibility or pilot studies with small sample sizes, there is a need for a randomized controlled trial with sufficient statistical power.Methods: The current study used a randomized controlled trial (n = 128) to test the efficacy of FLOW-VRT-Relaxation by comparing it to traditional relaxation practice in palliative care.Results: Our results showed that following a FLOW-VRT-Relaxation session, the symptoms of distress that patients in palliative care have to endure significantly reduced, whether physical or emotional in nature.Discussions: The current findings provide promising results regarding the therapeutic potential of using FLOW-VRT-Relaxation as a cost-effective, scalable, and personalized VR relaxation for patients in palliative care.
Effect of Combined High-Pressure Homogenization and Biotechnological Processes on Chitin, Protein, and Antioxidant Activity of Cricket Powder-Based Ingredients
Authors: Rossi Samantha , Gottardi Davide , Barbiroli Alberto , Di Nunzio Mattia , Siroli Lorenzo , Braschi Giacomo , Schlüter Oliver , Patrignani Francesca , Lanciotti Rosalba 
Published: January 2024

The main objective of this work was to evaluate the combined effect of a biotechnology process, based on selected yeast strains, and a high-pressure homogenization (HPH) treatment on the microbiological quality, structural organization of proteins, chitin content, and antioxidant activity of a mixture of cricket powder (Acheta domesticus) and water. Compared to untreated samples, the cricket matrix treated with HPH four times at 180 MPa promoted the growth of the inoculated Yarrowia lipolytica and Debaryomyces hansenii strains. HPH did not affect the concentration of chitin; however, the combination with microorganisms tended to reduce the content. Although the antioxidant activity increased from 0.52 to 0.68 TAC mM/TE after a 48 h incubation in the control, it was further improved by the combination of HPH and D. hansenii metabolism, reaching a value of 0.77 TAC mM/TE. The combination of the two approaches also promoted a reduction in the intensity of bands with molecular weights between 31 and 21.5 kDa in favor of bands with a lower molecular weight. In addition, HPH treatment reduced the number of accessible thiols, suggesting protein structure changes that may further impact the technological properties of cricket powder.
Immune Indicators in Children with Limited Scleroderma at Different Stages of the Disease
Authors: Мун А.В. , Дин П.Р. 
Published: January 2024

Введение. На основании проведенных исследований дана оценка клеточного и гуморального иммунитета в крови у детей с ограниченной склеродермией (ОС) в зависимости от стадии заболевания. Установлены некоторые иммунные звенья патогенеза заболевания, выявлены диагностические маркеры, характеризующие остроту процесса и позволяющие корректировать терапию в зависимости от стадии процесса. Цель. Изучить показатели иммунитета при ограниченной склеродермии у детей на разных стадиях заболевания. Материалы и методы. Проведен клинический и иммунологический анализ у 68 детей с ограниченной склеродермией. Результаты. Выявлен иммунодефицит в Т-клеточном звене иммунитета, проявляющийся подавлением активности CD3+, CD4+, CD8+, повышением активности СD20+. Выявлено достоверное повышение числа активированных В-лимфоцитов – СD20+. На стадии эритемы и отека наблюдается повышение числа В-лимфоцитов в 2,8 раза, а на стадии склерозирования и атрофии – в 1,8 раза. Выводы. В-лимфоциты играют важную роль в патогенезе аутоиммунных заболеваний, что также явилось важным диагностическим и прогностическим маркером ОС у детей.
Introduction. Based on the studies conducted, an assessment of cellular and humoral immunity in the blood of children with limited scleroderma, depending on the stage of the disease, was given. Some immune links in the pathogenesis of the disease have been established, diagnostic markers have been identified that characterize the severity of the process and make it possible to adjust therapy depending on the stage of the process. Purpose. To study immunity indicators in limited scleroderma in children at different stages of the disease. Materials and methods. A clinical and immunological analysis of 68 sick children with limited scleroderma was carried out. Results. Immunodeficiency in the T-cell immunity was revealed, manifested by suppression of the activity of CD3+, CD4+, CD8+, and increased activity of CD20+. A significant increase in the number of activated B-lymphocytes – CD20+ was revealed. At the stage of erythema and edema, an increase in the number of B-lymphocytes is observed by 2.8 times, and at the stage of sclerosis and atrophy – by 1.8 times. Conclusion. B-lymphocytes play an important role in the pathogenesis of autoimmune diseases, which has also become an important diagnostic and prognostic marker of LS in children.
Cutaneous Larva Migrans with Atypical Localization: Case Report
Authors: Тихоновская И.В. , Лесничая О.В. , Окулич Н.Ф. 
Published: January 2024

Кожная Larva migrans (LM) самая частая инфекция у туристов, возвращающихся из тропических стран. Причиной LM является внедрение в кожу личинки (третья стадия развития) анкилостомоза животных: Ancylostoma Brasiliense, A. caninum, A. ceylonicum, Uncineria stenocephala и Bubostomum phlebotomum. Человек для этих возбудителей является тупиковым хозяином. Чаще всего LM вызывает A. Brasiliense (анкилостома собак). Типичная локализация для инфекции – кожа стопы. В статье описан случай Larva migrans у белорусской туристки после отдыха в Шри-Ланке с необычной локализацией на коже спины.
Cutaneous Larva migrans (LM) is the most common infection among tourist returning from tropical countries. The cause of LM is inoculation into the skin of the larva of the animal hookworm (Ancylostoma Brasiliense, A. caninum, A. ceylonicum, Uncineria stenocephala, Bubostomum phlebotomum). For LM human is a dead – end host. Ancylostoma Brasiliense is the most cause agent of LM. The typical localization of infection is foots. In this article case of LM in a Belarusian tourist with unusual localization on back skin was described.
EDUKASI PUZZLE-8 MENGGUNAKAN
Authors: Afdhal Muhammad , Rita  , Saputra Dhio 
Published: January 2024

Susunan Puzzle-8 merupakan game edukasi yang paling pertama dipelajari oleh anak anak khususnya TK Paud dalam mengenal angka 1- 10. Game ini sangat di sukai oleh anak anak yang baru mengenal angka dan digabungkan dengan sistem game agar anak anak tertarik untuk mempelajari susunan hitungan angka tersebut. Tujuan penelitian ini yaitu untuk membantu anak anak TK Paud untuk mempelajari hitungan angka serta manfaat lain dalam game ini adalah mengasa perkembangan daya otak, game ini sangat bermanfaat untuk meningkatkan daya ingat dan disertai dengan konsep belajar sambil bermain. Algoritma Ascent Hill Climbing memiliki ketentuan dalam melakukan proses penyelesaian diantarnya 1. Mulai dari keadaan awal lakukan pengujian , jika merupakan tujuan , maka berhenti, jika tidak, lanjutkan dengan keadaan sekarang sebagai keadaan awal. 2. Kerjakan hingga tujuan tercapai atau iterasi tidak memberikan perubahan pada keadaan sekarang. 3.Jika posisi lebih baik daripada nilai heuristik keadaan sekarang , ubah nilai dengan keadaan Sekarang. 3 masalah yang harus diperhatikan dalam algoritma Stepest Ascent Hill Climbing diantaranya Local Optimum, keadaan semua tetangga lebih buruk atau sama dengan keadaan dirinya, Plateur, keadaan semua tetangga sama dengan keadaan dirinya, Ridge lokal optimum yang lebih disebabkan karena ketidakmampuan untuk menggunakan operator 2 sekaligus. Hasil penelitian data ini posisi puzzle sudah sama dengan keadaan awal dengan nilai posisi 1-8 sudah berapa pada posisi Goal Terakhir, sehingga pencarian diberhentikan
Strategi Peningkatan Kebutuhan Sistem Jaringan Air Bersih Di Desa Ledu-Ledu, Kecamatan Wasuponda
Authors: Yoriyelsa Yoriyelsa , Arief Rimba , Azis Fuad 
Published: January 2024

Abstract. This study aimed to determine the factors causing the availability of clean water in Ledu-Ledu Village, which is still limited, and what are the strategic directions for increasing the need for a clean water system in Ledu-Ledu Village. The data obtained will then be analyzed using scoring analysis dan SWOT analysis. From the results of the scoring analysis, it can be concluded that 2 (two) factors cause the availability of clean water in Ledu-Ledu Village to be still limited, namely the relatively low rainfall factor of between 2500-3000 mm, and the technological factor which is still lacking in quantity. So the strategy used is the WO strategy which minimizes weaknesses by taking advantage of opportunities.

Abstrak. Penelitian ini bertujuan untuk mengetahui faktor penyebab ketersediaan air bersih di Desa Ledu-Ledu masih terbatas dan bagaimana arahan strategi peningkatan kebutuhan sistem jaringan air bersih di Desa Ledu-Ledu. Data yang diperoleh selanjutnya akan dianalisis dengan menggunakan analisis skoring dan analisis SWOT. Dari hasil analisis skoring dapat disimpulkan bahwa terdapat 2 (dua) faktor yang menyebabkan ketersediaan air bersih di Desa Ledu-Ledu masih terbatas, yaitu faktor curah hujan yang relative rendah antara 2500-3000 mm, dan faktor teknologi yang secara kuantitas masih kurang. Sehingga strategi yang dilakukan adalah strategi WO meminimalisir kelemahan dengan memanfaatkan peluang.
Intermarriage-born Millennials in the Whirlwind of the 1990s Yugoslav Wars
Authors: Lendák-Kabók Karolina 
Published: January 2024

Abstract
The goal of this paper is to investigate the role of family choices regarding the language of education in self-representations in the adult life of millennials, who grew up during the 1990s Yugoslav wars in Vojvodina. Although the armed conflicts of the 1990s Yugoslav wars avoided Vojvodina, the war had a profound effect on the region. For intermarriage-born millennials, one of the milestone events in their lives is their parents’ choice of language of instruction when enrolling them in elementary school. The paper is based on an in-depth analysis of interviews conducted with millennials born in Serb-Hungarian intermarriage. The findings show the influence the choice of language of school instruction has on the millennials’ identity and sense of belonging. Those who attended minority language tuition endured more ethnicity-based, nationalism-fuelled incidents during their schooling. This topic is important, since the experiences of intermarriage-born millennials in Vojvodina had previously been neglected because of the focus on Serb-Croatian-Bosnian relationships in conflict literature.
Antibacterial effect of Cappariloside (C22H28N2O11) and Vitexlactam (C22H35NO4) alkaloids compounds isolation from Capparis spinosa roots & Vitex agnus-castus fruits.
Authors: Abies Ahmad , Basim Abdul hameed Diana , Farahan Mayada 
Published: January 2024

The isolation of alkaloids compounds from Capparis spinosa roots and Vitex agnus-castus fruits as crystal yellowish white powder. The chemical and physical properties of isolated alkaloids compounds were studied by using thin layer chromatography (TLC), melting point (MP), ultraviolet spectrum (UV) and FTIR spectrum. The isolated alkaloids compounds are shown high antibacterial activity against pathogenic bacteria (S. aureus, P. aeruginosa, P. stutzeri, E. aeruginosa, S. viridans, and S. pneuomonia). The results explained broad spectrum antibacterial property of alkaloids compounds against all pathogenic bacteria.
Assessment of Thrombospondin-1 Level in Type II Diabetic Patients
Authors: Al-Kraity Wijdan Rajh Hamza , Al-Dugaili Arshad Noori Ghani 
Published: January 2024

The study is intended to asses serum levels of Thrombospondin-1, fasting blood glucose in type 2 diabetic patients, also correlation between Thrombospondin-1 in both males and females. The study was conducted on randomly selected 65 type 2 diabetic patients (34 males and 31 females) attending the diabetes mellitus center in Al-Sadder Teaching City in Al- Najaf province , Iraqi and a group of 24 apparently healthy subjects (12 Males and 12 Females) were included as a control group . The Study was carried out from August 2013 to February 2014.The patients' age was ranging from 35 to 64 years old. The results indicated a significant increase (p<0.05) in serum FBG and TSP-1 levels in diabetic patients in comparing with healthy groups. The results also revealed no significant differences (p> 0.05) in serum TSP-1 levels between males and females in both patients and healthy groups, while the results of FBG levels significantly (p<0.05) increase in females than males in both patients and healthy groups. The results have been shown significant positive correlation (P<0.05) between TSP-1 and FBG in (males and females), males, females DM patients. The present study concluded that Thrombospondin-1 were marker for detection and diagnosis of diabetic patients type 2.
Assessment of Some Trace Elements , (MDA) and Protein Levels in Infertile Men
Authors: Falah A. Annooz Zahraa , S. M. AL Sallami Alaauldeen 
Published: January 2024

This study was performed on human semen specimens obtained from Asthenospermic patients (35 specimens) Normospermic males (40 specimens) , and (20 specimens ) Fertile Control group, who were attending to the laboratories of Fertility center in ALSader medical city of AL-Najaf AL-Ashraf city during the period extended from 1-9-2013 to 30-1 - 2014 . The aim of present study was to estimate the levels of some Trace element (Lead, Copper, Cobalt, Chromium, , and Cademium) concentrations in Asthenospermia and Normospermia. by atomic absorption method , and compersion with control (Fertile) .Estimate concentration of (MDA) Malondialdehyde ,Total protein concentration in semen specimens .Also relationships between mentioned components and some semen parameters . The results revealed significant increase (P <0.05) in the concentration of examined trace elements in Asthenospermia and Normozoospermia when compersion with control , and the study was appeared significant increase (P <0.05) in total protein concentration , also in MDA concentration in semen specimens. It was concluded that found increase in concentration of trace elements and it influence on blance and parameter of seminal fluid , also the Correlation between trace element and Protein in semen . All of this lead to arise of cases of Asthenospermia and Normospermia infertile patients .
RT-PCR detection of SAP1 gene in Candida albicans isolated from Meningitis cases
Authors: A. Hmood Baheeja 
Published: January 2024

Objective : The main objective of the sampling is to isolate fungi associated with cases of meningitis ,study of some Virulence factors of fungi and sensitivity to antifungal agents.Methods: 100 CSF sample were suspected of meningitis culture ,biochemical test and API-System for diagnosis of fungi in sample ,Real-time PCR based on SYBR Green I fluorescent dye for detection of sap gene in Candida albicans.Results: Depending on agricultures characteristics ,Biochemical tests and Api System the results showed that 32 samples, 32% were given the positive result for yeast growth, Candida albicans found in these samples by 87.5% and Cryptococcus neoformans 12.5% and 25(89.28%) of C.albicans isolates had Sap gene. C. albicans showed the lowest MICs (1 μg/ml) for amphotericin B. and higher MICs for fluconazole (4 - 32 μg/ml) and Nystatin (8-32 μg/ml) While C.neoformans showed low MICs for all antifungal agents used in this study ranged from (0.06-0.5 μg/ml) for amphotericin B and ( 0.25 - 1 μg/ml) for fluconazole and ( 1-4 μg/ml) for nystatinConclusion: Fungal Meningitis which caused by Candida albicans which have SAP gene that consider as virulence factors and Resistant to antifungal agents and Cryptococcus neoformans is a debilitating and potentially deadly disease that affects patients with both intact and impaired immune systems. early diagnosis and treatment is essential for optimal outcomes. Patients with Fungal Meningitis have multisystem disturbances and require a well-organized and executed plan of care.
IMMUNOLOGICAL PROFILE IN DIFFERENT GROUPS OF END STAGE RENAL DISEASE
Authors: Mohammed Sheet Saleh Madha , Ali Ahmed Zahraa 
Published: January 2024

Background and aim of study: End Stage Renal Disease (ESRD) is a worldwide problem in which patients are in hemo-dialysis and/or awaiting for kidney transplantation. However, the actual mechanism (s) of ESRD pathogenesis is ill-defined. The aim of this study is to investigate the role of certain immunological markers in the pathogenesis of ESRD. Materials and methods: Sixty eight blood samples were collected from hospitalized ESRD patients with different etiology (hypertensive, diabetics, hypertensive + diabetics, and small size kidney). Twenty healthy volunteers as control group was enrolled in the study. Serum IL-10, IL-17, MCP-1 and TGF-β were estimated in all subjects. Result: A significant elevation in the serum IL-10, MCP-1 and IL-17 mean concentration in all ESRD patients groups. TGF-β mean concentration exhibited decreasing level in the hypertensive, hypertensive + diabetes and small size kidney groups and a slight elevation in the diabetes group. The IL-10: IL-17 ratio expressed elevation in all ESRD patients groups.Conclusion: There is a progress of inflammatory reactions in all ESRD patients groups in which IL-17 and MCP-1 are playing major roles. TGF-β1 is not played its anticipated pro-fibrotic role and anti-inflammatory function in the studied group. The ratio of IL-10: IL-17 point out a slight shifting of the immunosuppressive reaction over the inflammatory reaction in all ESRD patients groups.