bluuebunny/crossref_metadata_2025_split huggingface dataset:
Developing a Business Maturity Framework (BMF) in the Oil and Gas Industry
Authors: Panduru Dan Andrei , Scarlat Cezar , Ioanid Alexandra 
Published: February 2024

This study explores the utility of business maturity models in navigating dynamic business landscapes. It assesses existing models, develops an industry-specific Business Maturity Framework (BMF), and emphasizes foundational considerations for effective implementation aligned with organizational goals. The study concludes by highlighting the perpetual nature of business maturity and the BMF's efficacy in enhancing operational excellence, competitiveness, and sustainable growth in the oil and gas sector. The paper contributes to specialized literature by introducing a novel dimension that evaluates market and customer readiness for future digitalization levels, thereby providing a comprehensive approach to business maturity.
Keywords: business transformation, digital process maturity, business maturity framework (BMF), incremental changes, maturity assessment, disruptive changes, oil and gas industry
Integrated Reporting and Group Decision-Making for Sustainable Development: A Bibliometric Review
Authors: Cunha Carlos , Duncan Luis 
Published: February 2024

The demands of society are constantly evolving, imposing significant pressures on business organizations within the context of sustainable development policy. As a result, organizations have begun to move towards promoting information disclosure through integrated reporting, transitioning from sustainability reports to financial reports. Simultaneously, decisions made to address specific problems are no longer the sole responsibility of a single individual. Challenges now revolve around group decision-making with the aim of achieving a consensus solution. To comprehend the landscape of integrated reporting and group decision-making in the scientific literature concerning sustainable development, a bibliometric review was conducted across major scientific databases from 2008 to 2023. The analysis utilized Bibliometrix, based on the R language, and Biblioshiny for graphic generation. The results indicate a quantitative increase in publications addressing integrated reporting and group decision-making in the context of sustainable development. However, a thematic isolation among existing studies was evident, pointing to an opportunity for future research to bridge the gap and establish more robust connections between the subjects.
Keywords: integrated reporting, group decision-making, sustainable development, bibliometric review
Wymieranie dinozaurów czeskiej sceny politycznej? Komunistyczna Partia Czech i Moraw w świetle wyborów z 2021 i 2022 roku
Authors: Koźbiał Krzysztof 
Published: February 2024

Komunistyczna Partia Czech i Moraw jest w zasadzie jedynym przykładem ugrupowania komunistycznego, które po transformacji ustrojowej przełomu lat 80. i 90. XX wieku przetrwało w systemie politycznym państwa w Europie Środkowej pod niezmienioną nazwą i tylko lekko zmodyfikowanym programie. Przez prawie 30 lat ugrupowanie odgrywało istotną rolę w czeskim systemie partyjnym, choć nie wchodziło w skład żadnego rządu czeskiego, wspierało jedynie od 2018 r. rząd premiera Babiša podczas poszczególnych głosowań.
W wyniku wyborów parlamentarnych z 2021 r. komuniści po raz pierwszy nie znaleźli się w Izbie Poselskiej, rok później uzyskali słaby wynik podczas wyborów samorządowych. W opinii autora wydarzenia te są prawdopodobnie początkiem znikania tej partii z krajobrazu politycznego Republiki Czeskiej. W 2023 r. KSČM nie była w stanie wystawić własnego kandydata w wyborach prezydenckich, co dodatkowo pogłębia kryzys.
Spadek poparcia jest spowodowany strukturą wyborczą głosujących na tę partię (są to z reguły ludzie starsi), brakiem interesującej oferty dla pozostałych wyborców, jak i kierowaniem swego przekazu głównie do niezadowolonych z transformacji. Znaczna część wyborców tej partii wybiera podczas głosowań inne ugrupowania, także prawicowe – jak SPD T. Okamury.
Exploring the role of sex in the association of late chronotype on cardiorespiratory fitness
Authors: Thomas J. Matthew , Kern Philip A. , Bush Heather M. , Robbins Sarah J. , Black W. Scott , Pendergast Julie S. , Clasey Jody L. 
Published: February 2024

AbstractCircadian rhythms differ between young adult males and females. For example, males tend to be later chronotypes, preferring later timing of sleep and activity, than females. Likewise, there are sex differences in body composition and cardiorespiratory fitness. Few studies have investigated the association between circadian rhythms, cardiorespiratory fitness, and body composition. We sought to determine whether chronotype and circadian phase were associated with cardiorespiratory fitness, body composition, and anthropometric measures in sedentary males and females. Fifty‐nine adults participated in the study. Circadian phase and chronotype were measured using dim light melatonin onset (DLMO) and the Morningness–Eveningness Questionnaire (MEQ) score. We used peak oxygen uptake (VO2peak) results from a maximal graded exercise test to assess cardiorespiratory fitness. Body composition, BMI, and circumferences were collected as markers of adiposity. We observed a sex difference in the association between DLMO and VO2peak. For males, a later DLMO was associated with a lower VO2peak. VO2peak did not vary based on DLMO in females. Later circadian phase was also associated with increased body fat percentage, fat mass index, and abdominal circumference in males, but not females. Collectively, these results suggest that males who are later chronotypes may be at risk of obesity and low cardiorespiratory fitness.
Tissue‐specific expression differences in Ras‐related GTP‐binding proteins in male rats
Authors: Kincheloe Gregory N. , Roberson Paul A. , Jefferson Leonard S. , Kimball Scot R. 
Published: February 2024

AbstractThe protein kinase Mechanistic Target of Rapamycin (mTOR) in Complex 1 (mTORC1) is regulated in part by the Ras‐related GTP‐binding proteins (Rag GTPases). Rag GTPases form a heterodimeric complex consisting of either RagA or RagB associated with either RagC or RagD and act to localize mTORC1 to the lysosomal membrane. Until recently, RagA and RagB were thought to be functionally redundant, as were RagC and RagD. However, recent research suggests that the various isoforms differentially activate mTORC1. Here, the mRNA expression and protein abundance of the Rag GTPases was compared across male rat skeletal muscle, heart, liver, kidney, and brain. Whereas mRNA expression of RagA was higher than RagB in nearly all tissues studied, RagB protein abundance was higher than RagA in all tissues besides skeletal muscle. RagC mRNA expression was more abundant or equal to RagD mRNA, and RagD protein was more abundant than RagC protein in all tissues. Moreover, the proportion of RagB in the short isoform was greater than the long in liver, whereas the opposite was true in brain. These results serve to further elucidate Rag GTPase expression and offer potential explanations for the differential responses to amino acids that are observed in different tissues.
Renal Tubular Acidosis in the Neonate
Authors: Lee Brian R. 
Published: February 2024

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Metabolic acidosis can manifest in the neonatal period and cause significant morbidity and mortality in neonates. Preterm infants are at an even higher risk of developing metabolic acidosis. If the acidosis results from a dysfunction of acid-base homeostasis by the renal system, the disorder is known as renal tubular acidosis (RTA). In this review, we will describe renal development and normal acid-base homeostasis by the renal system. We will also discuss the pathophysiology of the different types of RTA, laboratory findings to aid in diagnosis, and treatment considerations. Understanding RTA will help neonatal clinicians recognize and diagnose an infant affected by RTA and initiate treatment in a timely manner.
“Die Natur ist hier … zu Musik geworden”: György Ligeti and (Musical) Nature
Authors: Schreiber Ewa 
Published: February 2024

AbstractThis article traces references to nature and naturalism (understood as an attempt to ground and legitimize art in natural phenomena) in Ligeti's writings, but also in selected aspects of his oeuvre. The references to nature recur here in various manifestations, with romantic depictions of nature appearing alongside more recent, modernist approaches. The concept of nature is associated with the romantic setting for human emotions, with the discovery of scientific laws, with listening to soundscape, with phenomena of auditory perception and with the spectral explorations of sound. Although nature is not a central, strategic concept for Ligeti, it remains a constant, even if hidden, context for his work, a point of reference.
Patient and Public Perceptions in Canada about Decentralized and Hybrid Clinical Trials: “It’s about time we bring trials to people”
Authors: Richards Dawn P. , Queenan John , Aasen-Johnston Linnea , Douglas Heather , Hawrysh Terry , Lapenna Michael , Lillie Donna , McIntosh Emily , Shea Jenna , Smith Maureen , Marlin Susan 
Published: February 2024

Abstract
Background
Little is known about patient and the public perspectives on decentralized and hybrid clinical trials in Canada.
Methods
We conducted an online survey (English and French) promoted on social media to understand perspectives of people in Canada about decentralized and hybrid clinical trials. The survey had two sections. We co-produced this project entirely with patient, caregiver, and family partners.
Results
The survey had 284 (14 French) individuals who started or completed section 1, and 180 (16 French) individuals who started or completed section 2. People prefer to have options to participate in clinical trials where aspects are decentralized or hybridized. Seventy-nine percent of respondents preferred to have options related to study visits. There were concerns about handling adverse events or potential complications in decentralized trials, however, communication options such as a dedicated contact person for participants was deemed helpful. Most respondents were amenable to informed consent being done at a satellite site closer to home or via technology and were split on privacy concerns about this. Most preferred travel to a site within an hour, depending on what the trial was for or its impact on quality of life. Due to the response rate, we were unable to explore associations with gender, age, health status, geography, ethnicity, and prior clinical trial participation.
Conclusion
Our findings indicate an openness in Canada to participating in trials that decentralize or hybridize some aspects. These trials are perceived to provide benefits to participants and ways to increase equity and accessibility for participants.
REG1A may be a new biological marker for diagnosing sepsis
Authors: Li Yang , Guo Wentao , Chen Wenhao , Wang Chenglin , Li Shilin , Shen Yuzhou , Chen Muhu 
Published: February 2024

Abstract
Objective
The aim of this study was to analyze the proteomic mass spectrometry of sepsis patients as well as normal subjects, and then to explore the characteristic proteins related to the pathogenesis of sepsis, and then to provide the basis for the clinical diagnosis and treatment of sepsis.
METHODS
Peripheral blood specimens from sepsis patients (n = 17) and normal subjects (n = 8) were analyzed by proteomic mass spectrometry sequencing, and the R-based Integrated Differential Expression and Pathway Analysis (iDEP) (http://bioinformatics.sdstate.edu/idep/) web tool was used to screen and analyze differentially expressed genes (iDEPs) and low-expressed genes (iDEPs). Screening analysis finalized the differentially expressed genes (DEGs, log2FC ≥ 1, P value ≤ 0.05). Differential proteins were screened for potential core proteins by enrichment analysis and combined with the subjects' work characterization curves (ROC curves), and finally the analysis results were verified by ELISA experiments.
RESULTS
Differential proteins were finally screened by the analysis, and the results were validated by ELISA to clarify that REG1A has a guiding significance in the diagnosis, differential diagnosis, and prognosis of sepsis disease.
CONCLUSION
Bioinformatics analysis of protein expression profiles in this study identified that the protein REG1A may represent a molecular mechanism for the onset, progression, and risk prediction of sepsis.
Effect of dietary supplementation of wild leek (Allium tricoccum) and garlic ( Allium sativum) leaves on production, egg quality, serum lipid profile, intestinal morphology and digestibility of laying quails
Authors: Abdulkareem Zana Azeez 
Published: February 2024

Abstract

In this study, the effects of adding dried wild leek and garlic leaves to the diet of laying quails on egg quality, production performance, intestinal histomorphology, digestibility, and serum biochemical traits were evaluated. 168 − 30 weeks aged- laying quails were randomly arranged into 7 treatments (control group and three different levels (0.5%, 1%, and 1.5%) of wild leek or garlic leaves), 6 replicates, and 4 quails per pen. According to the study, the highest hen-day production was achieved by adding 0.5% garlic leaves, and the egg weight was higher with 1% garlic leaves and 0.5% wild leek compared to the control group (P < 0.05). In addition, adding garlic leaves decreased the average daily feed intake and increased high-density lipoprotein concentration. However, adding both herbs did not influence yolk height, albumin height, shell thickness, and Haugh unit (P > 0.05). All supplemented treatments significantly increased the Rouch index compared to the control. Quails fed with 1% garlic leaves experienced serum cholesterol, very low-density lipoprotein, low-density lipoprotein, and uric acid. Moreover, three levels of garlic leaves decreased Triglyceride concentration. Adding 0.5% and 1% garlic leaves to the diet could increase the digestibility of ash, crude protein, jejunal, and ileal villus height-to-crypt depth ratio. Furthermore, 1% and 1.5% garlic leaves supplementation elevated organic matter digestibility. In conclusion, supplementing 1% garlic leaves to the quail's diet could improve egg weight, intestinal morphology, and nutrient digestibility, improving lipid profiles and reducing uric acid concentration in the serum. However, both plants were rich pigment sources, increasing the rouch index.
Absence of platelet overactivation and thrombosis formation among patients with coronary atherosclerosis disease after vaccination against SARS-CoV-2
Authors: Xu Huajie , Zhao Xin , Zhang Peng , Zhou Qi , Fan Bing , Zhang Si , Wu Hongyi 
Published: February 2024

Abstract
Background
Association of Coronavirus disease 2019 vaccines with thrombosis has raised concerns among patients with coronary atherosclerosis disease (CAD).
Objectives
After vaccination against SARS-CoV-2, to detect thrombosis formation in atherosclerosis ApoE−/− mice, and platelet activation, coagulation, the profile of prothrombotic antibodies, and the production of platelet factor 4 (PF4) antibodies in patients with CAD.
Methods
Atherosclerotic ApoE−/− mice were immunized with saline or inactivated SARS-CoV vaccines. We investigated FeCl3-induced thrombus formation in vivo, and thrombus formation under flow conditions ex vivo. Inpatients undergoing percutaneous coronary intervention (PCI) were consecutively enrolled and defined according to vaccination status. We evaluated coagulation by thrombelastograph (TEG), platelet activation makers by flow cytometry, PF4 antibody and antiphospholipid antibodies by ELISA, and SARS-CoV-2 neutralizing antibody.
Results
In atherosclerotic ApoE−/− mice, FeCl3-induced thrombus formation and thrombus formation under flow conditions were similar between saline-treated and inactivated SARS-CoV-2 vaccines-treated groups. A total of 182 patients undergoing PCI were included in the final analysis, of whom 92 had been vaccinated. Baseline characteristics were well balanced between unvaccinated and vaccinated groups. The expression of PAC-1 and P-selectin, the prevalence of positivity for PF4 antibodies and antiphospholipid antibodies were similar between these two groups.
Conclusions
Inactivated SARS-CoV-2 vaccines did not potentiate thrombosis formation in atherosclerotic mice. Inactivated SARS-CoV-2 vaccines did not enhance platelet activation, or trigger the production of PF4 and antiphospholipid antibodies in patients with CAD. Our data adds evidence to the safety profile of the inactivated SARS-CoV-2 vaccines.
Separation and Cultivation of Calcified Nanoparticles in Gallstones: A Related Study
Authors: Wang Meiyan , Su Xuanli , Yang Jian , Shi Haojie , Niu Sanqiang , He Yufan , Li Zhenhao 
Published: February 2024

Abstract

This study aims to explore effective and feasible methods for the separation and cultivation of calcified nanoparticles using obtained gallstones as an example. It also investigates the relationship between calcified nanoparticles and the formation of gallstones. These findings provide a fundamental basis for further research on the characteristics and applications of calcified nanoparticles.
Methods:
1. Twenty gallstone samples were surgically collected from patients at the First Affiliated Hospital of Shihezi University between March and May 2023.
Informed consent: Informed consent has been obtained from all individuals included in this study.
Ethical approval:The research related to human use complies with all relevant national regulations and institutional policies, adhering to the principles of the Helsinki Declaration. All methods are conducted in accordance with relevant guidelines and regulations. It has also been approved by the Institutional Review Board of the First Affiliated Hospital of Shihezi Medical University.(approval number: KJX2022-107-01, date: 2022/1/10).
2. Gallstone specimens underwent hydrochloric acid demineralization and bacterial filtration methods to isolate calcified nanoparticles.
3. The isolated calcified nanoparticles were cultured in a cell culture incubator for four weeks. A comparison was made with a blank control group to observe the presence of white precipitates at the bottom of the tube.
4. Purified calcified nanoparticles were collected and analyzed using electron microscopy.
Results:
1. Calcified nanoparticles were successfully isolated and extracted from gallstone specimens.
2. The presence of calcified nanoparticles suggests their potential contribution to gallstone formation.
3. Elemental analysis of calcified nanoparticles revealed the predominance of inorganic components such as calcium, phosphorus, and silicon.
Conclusion: Calcified nanoparticles have been identified in gallstones and may play a significant role in the formation of gallstones. However, the exact nature and mechanism of calcified nanoparticles in stone-related diseases are yet to be fully understood. Therefore, further research is required to explore and elucidate the role of calcified nanoparticles in gallstone formation.
Placental and Cleft Palate: Preliminary Insights from Integrated Metabolomic and Transcriptomic Analyses
Authors: Lin Lanling , Wei Mianxing , Luo Xiao , Zhang Chong , Jing Bingshuai , Wang Jue , Shi Bing , Gong Meng , Li Chenghao 
Published: February 2024

Abstract

The correlation between glucocorticoids and cleft palate, a prevalent congenital abnormality, remains controversial, particularly concerning the uncertain status of placenta-palate formation. Utilizing a dexamethasone-induced cleft palate model in New Zealand rabbits, an integrated analysis of untargeted metabolomics and transcriptomics was conducted to explore the correlation between placental pathology and cleft palate. After dexamethasone treatment, approximately 60% of rabbit embryos developed cleft palates. Obvious pathologic change were observed on placenta including fibrosis, calcification, and necrosis. Transcriptomic analysis identified 4,744 differentially expressed genes in the placenta, involving pathways related to hormonal responses, vascular development, and inflammatory reactions. Metabolomic data revealed significant metabolic differences in both the placenta and amniotic fluid, with notable increases in urea levels in the placenta, while urea and arginine levels were markedly reduced in the amniotic fluid. Furthermore, metabolic disruptions in urea cycle, particularly an increase in arginase activity, may related to placental pathological changes. Overall, there is a correlation between placental pathology and cleft palate. Disruption of the urea cycle may contribute to placental lesions associated with the development of cleft palate. This offers a novel direction for understanding the mechanism of cleft palate formation, suggesting a potential significant role of placental metabolic disorders.
A Middle Tithonian ammonite faunula from the historical outcrop ofMonte Acuto (Cantiano, Umbro-Marchean Apennine, Italy)
Authors: Nannarone Carlo , Bilotta Massimiliano 
Published: February 2024

Abstract
The Middle Tihonian ammonite assemblage found in a single bank (with a total thickness of about 30 cm and subdivided in two beds), from the classic Monte Acuto outcrop originarily quoted in the second half of the nineteenth century, is here described. From the micritic matrix 20 ammonite specimens were extracted, belonging to 13 species, among which one, here dubitatively ascribed to Cordubiceras, was previously devoid of a formal designation and represents the first possible record of such a genus in central Italy. The fauna is dated to the Volanense Zone of the standard Mediterranean scheme.
Factors Associated with Breastfeeding Exclusivity in Akure, Nigeria
Authors: Adesanoye Joy K. , Isiugo-Abanihe Uche C. 
Published: February 2024

Abstract
Malnutrition and mortality persistently affect the health and survival of Nigerian children, despite government efforts through policies and program interventions. In response to this, this study examined how the socio-economic characteristics of mothers impact the attainment of breastfeeding exclusivity. The goal is to trace the problem of non-adoption of interventions back to its roots. "The study employed the triangulation of quantitative and qualitative methods of data collection from a sample of 406 women found at the immunization and antenatal clinics of two key hospitals in Akure. These women had their last birth in the three years before the survey. Qualitative data were analyzed using content analysis, while descriptive and inferential statistics were obtained for the quantitative data, using simple percentages, chi-square statistic to test relationships, and logistic regression to evaluate the influence of socio-economic and maternal factors on attainment of exclusivity. A total of 396 eligible women were included in the final sample. Nearly all women (99.5%) ever breastfed their infants and 60% have high knowledge of breastfeeding though less than half (42%) of women achieved early initiation. More than half of women (53%) achieved exclusive breastfeeding as against the generally low rate found in Nigeria as a whole. The study found an association between place of delivery and attainment of early breastfeeding initiation and exclusivity. Maternal and socio-economic factors like mother’s age, income, and breastfeeding knowledge influence attainment of exclusivity at 95% confidence level. Akure and Nigeria at large have not yet hit their target at promoting the health and survival of infants and young children as the findings still fall below the 90% WHO/UNICEF recommendation in children less than 6 months in developing countries