bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quantitative Magnetic Resonance Imaging for Neurodevelopmental Outcome Prediction in Neonates Born Extremely Premature—An Exploratory Study
Authors: Schmidbauer Victor U. , Yildirim Mehmet S. , Dovjak Gregor O. , Goeral Katharina , Buchmayer Julia , Weber Michael , Kienast Patric , Diogo Mariana C. , Prayer Florian , Stuempflen Marlene , Kittinger Jakob , Malik Jakob , Nowak Nikolaus M. , Klebermass-Schrehof Katrin , Fuiko Renate , Berger Angelika , Prayer Daniela , Kasprian Gregor , Giordano Vito 
Published: January 2024

Abstract
Purpose
Neonates born at < 28 weeks of gestation are at risk for neurodevelopmental delay. The aim of this study was to identify quantitative MR-based metrics for the prediction of neurodevelopmental outcomes in extremely preterm neonates.

Methods
T1-/T2-relaxation times (T1R/T2R), ADC, and fractional anisotropy (FA) of the left/right posterior limb of the internal capsule (PLIC) and the brainstem were determined at term-equivalent ages in a sample of extremely preterm infants (n = 33). Scores for cognitive, language, and motor outcomes were collected at one year corrected-age. Pearson’s correlation analyses detected relationships between quantitative measures and outcome data. Stepwise regression procedures identified imaging metrics to estimate neurodevelopmental outcomes.

Results
Cognitive outcomes correlated significantly with T2R (r = 0.412; p = 0.017) and ADC (r = −0.401; p = 0.021) (medulla oblongata). Furthermore, there were significant correlations between motor outcomes and T1R (pontine tegmentum (r = 0.346; p = 0.049), midbrain (r = 0.415; p = 0.016), right PLIC (r = 0.513; p = 0.002), and left PLIC (r = 0.504; p = 0.003)); T2R (right PLIC (r = 0.405; p = 0.019)); ADC (medulla oblongata (r = −0.408; p = 0.018) and pontine tegmentum (r = −0.414; p = 0.017)); and FA (pontine tegmentum (r = −0.352; p = 0.045)).
T2R/ADC (medulla oblongata) (cognitive outcomes (R2 = 0.296; p = 0.037)) and T1R (right PLIC)/ADC (medulla oblongata) (motor outcomes (R2 = 0.405; p = 0.009)) revealed predictive potential for neurodevelopmental outcomes.

Conclusion
There are relationships between relaxometry‑/DTI-based metrics determined by neuroimaging near term and neurodevelopmental outcomes collected at one year of age. Both modalities bear prognostic potential for the prediction of cognitive and motor outcomes. Thus, quantitative MRI at term-equivalent ages represents a promising approach with which to estimate neurologic development in extremely preterm infants.
Influence of COVID-19 pandemic on hospitalisations at a paediatric traumatology department during 2020: a single-centre observational study and comprehensive literature review
Authors: Delbrück Heide , Lambertz Ellen , Migliorini Filippo , Berger Nina , Hildebrand Frank 
Published: January 2024

Abstract
Purpose
The study investigates changes in the injury characteristics of hospitalised children in a paediatric trauma centre during the COVID-19 pandemic.

Methods
Data from injured children from the pre-pandemic year 2019 were compared to the pandemic year 2020 using Pearson’s chi-squared test and the Mann–Whitney U test. The period of highly restrictive regulations (HRP) was evaluated separately. A comprehensive literature review with defined search terms resulted in a descriptive data synthesis.

Results
Data from 865 patients indicated reductions in admissions of 5.6% and 54.4% during the HRP. In 2020, the hospitalisation time was longer (2.2 ± 2.7 days in 2019 vs. 2.4 ± 2.6 in 2020, p = 0.045); the proportions of wounds requiring surgical therapy (p = 0.008) and of observational treatments, primarily for mild brain injuries (p = 0.046), were higher; and conservative treatments, primarily for contusions, were lower (p = 0.005). There were no significant changes in age, location of lesions, or frequency of surgical therapy; nor were there differences in the HRP, except for fewer injuries in school and kindergarten (p < 0.001). The literature review summarises the main results of 79 studies.

Conclusion
Limited resources did not alter the indications for surgical therapy. Further studies should examine whether the more common injuries sustained at home were caused by excessive work/childcare demands on parents. Reduced inpatient conservative treatment implies that hospital resources possibly were overused previously. The literature offers answers to many detailed questions regarding childhood injuries during a pandemic and more efficient safe treatment.
Registration Ethical committee of RWTH Aachen University EK 22-320; Center for Translational & Clinical Research RWTH Aachen University (CTC-A) 21-430.
Robust Channels: Handling Unreliable Networks in the Record Layers of QUIC and DTLS 1.3
Authors: Fischlin Marc , Günther Felix , Janson Christian 
Published: January 2024

AbstractThe common approach in secure communication channel protocols is to rely on ciphertexts arriving in-order and to close the connection upon any rogue ciphertext. Cryptographic security models for channels generally reflect such design. This is reasonable when running atop lower-level transport protocols like TCP ensuring in-order delivery, as for example, is the case with TLS or SSH. However, protocols like QUIC or DTLS which run over a non-reliable transport such as UDP, do not—and in fact cannot—close the connection if packets are lost or arrive in a different order. Those protocols instead have to carefully catch effects arising naturally in unreliable networks, usually by using a sliding-window technique where ciphertexts can be decrypted correctly as long as they are not misplaced too far. In order to be able to capture QUIC and the newest DTLS version 1.3, we introduce a generalized notion of robustness of cryptographic channels. This property can capture unreliable network behavior and guarantees that adversarial tampering cannot hinder ciphertexts that can be decrypted correctly from being accepted. We show that robustness is orthogonal to the common notion of integrity for channels, but together with integrity and chosen-plaintext security it provides a robust analog of chosen-ciphertext security of channels. In contrast to prior work, robustness allows us to study packet encryption in the record layer protocols of QUIC and of DTLS 1.3 and the novel sliding-window techniques both protocols employ. We show that both protocols achieve robust chosen-ciphertext security based on certain properties of their sliding-window techniques and the underlying AEAD schemes. Notably, the robustness needed in handling unreliable network messages requires both record layer protocols to tolerate repeated adversarial forgery attempts. This means we can only establish non-tight security bounds (in terms of AEAD integrity), a security degradation that was missed in earlier protocol drafts. Our bounds led the responsible IETF working groups to introduce concrete forgery limits for both protocols and the IRTF CFRG to consider AEAD usage limits more broadly.
The Compressible Euler and Acoustic Limits from Quantum Boltzmann Equation with Fermi–Dirac Statistics
Authors: Jiang Ning , Zhou Kai 
Published: January 2024

AbstractThis paper justifies the compressible Euler and acoustic limits from quantum Boltzmann equation with Fermi–Dirac statistics rigorously. By employing Hilbert expansion, in particular analyzing the nonlinear implicit transformation between the classical form of compressible Euler equations and the one obtained directly from BFD, and some new type of Grad–Caflisch type decay estimate of the linearized collision operator, we establish the compressible Euler limit from scaled BFD equation, which was formally derived by Zakrevskiy in (Kinetic models in the near-equilibrium regime. Thesis at Polytechnique, 2015) by moment method. Consequently, the acoustic limit is obtained in optimal scaling with respect to Knudsen number.
Machine learning-based radiomic analysis and growth visualization for ablation site recurrence diagnosis in follow-up CT
Authors: Yin Yunchao , de Haas Robbert J. , Alves Natalia , Pennings Jan Pieter , Ruiter Simeon J. S. , Kwee Thomas C. , Yakar Derya 
Published: January 2024

Abstract
Objectives
Detecting ablation site recurrence (ASR) after thermal ablation remains a challenge for radiologists due to the similarity between tumor recurrence and post-ablative changes. Radiomic analysis and machine learning methods may show additional value in addressing this challenge. The present study primarily sought to determine the efficacy of radiomic analysis in detecting ASR on follow-up computed tomography (CT) scans. The second aim was to develop a visualization tool capable of emphasizing regions of ASR between follow-up scans in individual patients.

Materials and methods
Lasso regression and Extreme Gradient Boosting (XGBoost) classifiers were employed for modeling radiomic features extracted from regions of interest delineated by two radiologists. A leave-one-out test (LOOT) was utilized for performance evaluation. A visualization method, creating difference heatmaps (diff-maps) between two follow-up scans, was developed to emphasize regions of growth and thereby highlighting potential ASR.

Results
A total of 55 patients, including 20 with and 35 without ASR, were included in the radiomic analysis. The best performing model was achieved by Lasso regression tested with the LOOT approach, reaching an area under the curve (AUC) of 0.97 and an accuracy of 92.73%. The XGBoost classifier demonstrated better performance when trained with all extracted radiomic features than without feature selection, achieving an AUC of 0.93 and an accuracy of 89.09%. The diff-maps correctly highlighted post-ablative liver tumor recurrence in all patients.

Conclusions
Machine learning-based radiomic analysis and growth visualization proved effective in detecting ablation site recurrence on follow-up CT scans.
Type 1 and type 2 torpedo maculopathy
Authors: Rickmann Annekatrin , Bodenbender Jan-Philipp , Gelisken Faik , Kühlewein Laura 
Published: January 2024

Abstract
Purpose
To analyze torpedo maculopathy (TM) and to report the characteristics of the disease.

Methods
Retrospective study. The review of a database for clinical diagnosis identified eight patients with TM lesions in the retina between 2016 and 2022. Multimodal imaging was used to analyze the cases.

Results
All cases were unilateral, asymptomatic, and hypopigmented. They were associated by surrounding hyperpigmented retinal pigment epithelium changes to varying degrees. All lesions were located in the temporal retina on the horizontal axis, pointing towards the fovea, except for one patient with a lesion inferior to the fovea. Optical coherence tomography imaging revealed a normal inner retina in all eyes. In the area of the TM lesion, attenuation of the interdigitation zone was seen in mild cases (three cases). All other five patients had thinning of the outer nuclear layer and loss of ellipsoid zone and interdigitation zone of the TM lesion. Four of these cases had a subretinal cavitation/cleft, and two of them additionally an inner choroidal excavation. No patient had any sign of choroidal neovascularization. The average age for patients with type 1 TM was 18 years and for type 2 TM 16.5 years.

Conclusion
In this large case series, we could not detect an age difference between the different types of the TM. Contrary to previous discussions, type 2 TM can also occur in young patients.
Grenzregionen in der COVID-19-Pandemie: Wie der „Grenzschock“ die Oberrheinregion veränderte
Authors: Friedlaender Tobias , Müller Anna-Lisa 
Published: January 2024

ZusammenfassungAm Beispiel der trinationalen Oberrheinregion geht dieser Artikel der Frage nach, auf welche Weise sich die im Zuge der COVID-19-Pandemie im Jahr 2020 vollzogenen Grenzschließungen und die damit verbundenen Grenzerfahrungen auf die grenzüberschreitenden Beziehungen von lokalen Akteur*innen in Politik, Wirtschaft und Gesellschaft ausgewirkt haben. Anhand qualitativer Interviewdaten zeigen wir, wie dieser pandemiebedingte „Grenzschock“ aufgenommen und der grenzüberschreitende politische und soziale Zusammenhalt auf die Probe gestellt wurde, wie aber auch die Zusammenarbeit nach einer Zeit der Irritation an die neue Situation angepasst werden konnte. Dabei befand sich die grenzüberschreitende Zusammenarbeit in dieser Zeit in einem Spannungsfeld zwischen politisch-administrativen Vorgaben der jeweiligen nationalen Zentren und den lokal spezifischen Anforderungen einer peripher gelegenen Grenzregion. Die Daten zeigen, dass die Akteur*innen in der Oberrheinregion bei der Überwindung dieses „Grenzschocks“ auf langjährig etablierte Strukturen und Erfahrungen in der grenzüberschreitenden Zusammenarbeit zurückgreifen konnten. Die Erfahrungen während der Pandemie sorgten dabei zudem für neue Impulse für die grenzüberschreitende Zusammenarbeit in der Oberrheinregion und stärkten den politischen Willen dafür auf verschiedenen Ebenen. Damit leistet der Artikel einen explorativen Beitrag zu den Auswirkungen der COVID-19-Pandemie auf Grenzregionen.
Burden of osteoarthritis in China, 1990–2019: findings from the Global Burden of Disease Study 2019
Authors: Li Hongying , Kong Weisi , Liang Yan , Sun Huixin 
Published: January 2024

AbstractThis study aimed to report the most current data on the incidence and disability-adjusted life years (DALY) associated with osteoarthritis in China from 1990 to 2019. Publicly available modelled data from Global Burden of Disease Study (GBD) 2019 were used. The incidence and DALY, due to osteoarthritis in China, stratified by sex, trends of associated risk factors, assess the age, period, and cohort effects on the long-term trends of osteoarthritis incidence and DALY in China from 1990 to 2019. We found that the age-standardized incidence and DALY rates of osteoarthritis in China are higher than the average levels in Asia, Africa, and Oceania. In 2019, the number of cases of osteoarthritis in China was 10,681,311, an increase of 132.66% compared with 1990. the DALY of osteoarthritis in China was 4,724,885 person-years, which was 159.70% higher than that in 1990. In 2019, the incidence and DALY rates of osteoarthritis in China was 750.96/100,000,332.19/100,000. High body-mass as risk factors for osteoarthritis DALY with the population attributable proportion (PAF) increasing steadily from 1990 to 2019. The incidence and DALY rates of three types of osteoarthritis from high to low are osteoarthritis knee, osteoarthritis hand, and osteoarthritis hip. Age–period–cohort model showed that the incidence rate of osteoarthritis in China shows a trend of increasing first and then decreasing with age; concurrently, the DALY rate of osteoarthritis in China increased with age. For the period effect, we found that the period rate ratio (RR) of osteoarthritis incidence and DALY rates kept increasing in the cohort born before 2005–2009, and then, it was gradually reduced by year of birth in the cohort born after 2005–2009. As for cohort effect, the cohort RR of incidence rate of osteoarthritis almost has no change, while the cohort RR of DALY rate of osteoarthritis kept increasing from 1990 to 2019. The burden and impact of osteoarthritis in China are substantial and are increasing. Adopting suitable control and preventive community measures to reduce modifiable risk factors is needed to reduce the current and future burden of osteoarthritis in China.

Key Points• This paper analyzes the disease burden of osteoarthritis in China for the first time and discusses the influence on the disease burden of osteoarthritis from the perspectives of age, period, and cohort.
Mapping the spatiotemporal variability in global storm surge water levels using satellite radar altimetry
Authors: Bij de Vaate Inger , Slobbe Dirk Cornelis , Verlaan Martin 
Published: January 2024

AbstractMulti-mission satellite altimetry data have been used to study the spatial and temporal variability in global storm surge water levels. This was done by means of a time-dependent extreme value analysis applied to the monthly maximum detided water levels. To account for the limited temporal resolution of the satellite data, the data were first stacked on a $$\varvec{5}^{\varvec{\circ }} \times \varvec{5}^{\varvec{\circ }}$$

5

∘

×

5

∘

grid. Moreover, additional scaling was applied to the extreme value analysis for which the scaling factors were determined by means of a resampling method using reanalysis data. In addition to the conventional analysis using data from tide gauges, this study provides an insight in the ocean-wide storm surge properties. Nonetheless, where possible, results were compared to similar information derived from tide gauge data. Except for secular changes, the satellite-derived results are comparable to the information derived from tide gauges (correlation $$> \varvec{0.5}$$

>

0.5

), although the tide gauges show more local variability. Where limited correlation was observed for the secular change, it was suggested that the satellites may not be able to fully capture the temporal variability in the short-lived, tropical storms, as opposed to extra-tropical storms.
Preference learning and multiple criteria decision aiding: differences, commonalities, and synergies—part II
Authors: Hüllermeier Eyke , Słowiński Roman 
Published: January 2024

AbstractThis article elaborates on the connection between multiple criteria decision aiding (MCDA) and preference learning (PL), two research fields with different roots and developed in different communities. It complements the first part of the paper, in which we started with a review of MCDA. In this part, a similar review will be given for PL, followed by a systematic comparison of both methodologies, as well as an overview of existing work on combining PL and MCDA. Our main goal is to stimulate further research at the junction of these two methodologies.
The effects of European fiscal discipline measures on current account balances
Authors: Glebocki Keefe Helena , Hepp Ralf 
Published: January 2024

AbstractFollowing the European Debt Crisis, there was a significant push for greater fiscal discipline across the EU member states. This began with the revitalization of the Stability and Growth Pact in 2011 and continued with the adoption of the Fiscal Stability Treaty of 2013. The measures were designed to maintain or achieve both government debt-to-GDP ratios of below 60% and government budget deficits of below 3%. This paper investigates whether the fiscal discipline measures had an impact on the relationship between fiscal and current account balances. Using the synthetic control method, we examine current account balances in each EU member state that implemented the fiscal provisions in the treaty (Title III), compared to a synthetic counterfactual economy. We find that countries most impacted by the European Debt Crisis experienced the greatest improvement in their current account deficits from the fiscal discipline measures. Several other EU member states also experienced stabilization in their current account balances compared to their synthetic counterfactuals.
Exploring the trend of recognizing apple leaf disease detection through machine learning: a comprehensive analysis using bibliometric techniques
Authors: Bonkra Anupam , Pathak Sunil , Kaur Amandeep , Shah Mohd Asif 
Published: January 2024

AbstractThis study’s foremost objectives were to scrutinize how unexpected weather affects agricultural output and to assess how well AI-based machine learning and deep leaning algorithms work for spotting apple leaf diseases. The researchers carried out a bibliometric study to obtain understanding of the current research trends, citation patterns, ownership and partnership arrangements, publishing patterns, and other parameters related to early identification of apple illnesses. Comprehensive interdisciplinary scientific maps are limited because syndrome recognition is not restricted to any solitary arena of research, despite the fact that there have been many studies on the identification of apple diseases. By employing a scientometric technique and 109 publications from the Scopus database published between 2011 and 2022, this study attempted to assess the condition of the research area and combine knowledge frameworks. To find important journals, authors, nations, articles, and topics, the study used the automated processes of VOSviewer and Biblioshiny software. Patterns and trends were discovered using citation counts, social network analysis, and citation and co-citation studies.
Synthesis of high-performance biocompatible polymeric membranes incorporated with zirconium-based MOF for an enhanced brackish water RO desalination
Authors: Koriem Omneya A. , Showman Marwa S. , El-Shazly Ahmed H. , Elkady Marwa 
Published: January 2024

AbstractA nanosized zirconium 1,4- dicarboxybenzene metal-organic framework (UiO-66-MOF) was synthesized and impregnated into cellulose acetate (CA) polymeric matrix to enhance the membrane characteristics for brackish water desalination. Phase inversion was used for the fabrication of CA/UiO-66 hybrid membranes (CAU-X), where X is the concentration of immobilized UiO-66 nanoparticles (UiO-66-NPs) into CA polymeric matrix. Morphological structure and functional groups were investigated through different characterization techniques to prove the successful synthesis of the prepared UiO-66-NPs, the blank CA membrane, and hybrid CAU-X membranes. For more CAU-X characteristics, porosity, contact angle, and tensile strength were measured. The obtained data demonstrated that the impregnation of zirconium-based-NPs had a positive influence on the blank CA membrane properties. Additionally, the performance of the fabricated membranes was investigated in reverse osmosis (RO) bench-scale unit. The performance results for the pristine CAU-0 membrane showed a high salt rejection (SR) of 99.8% and a permeate water flux (PWF) of 1.14 L/m2.h. In comparison to pristine CA membrane, CAU-X hybrid membranes have a slightly lower SR and a higher PWF. It was found that the hybrid CAU-0.02 membrane had almost a doubled PWF of 2.8 L/m2.h with only 2% sacrificed SR of 97.6% compared with CAU-0 membrane. Moreover, a much better PWF of 3.4 L/m2h and a sufficient SR of approximetly 92% were obtained by CAU-0.05 membrane. Thus, CAU-0.05 was selected to further test its performance under different operating parameters. Results revealed that the optimum parameters were recorded for a sodium chloride feed stock of 5000 ppm operating at 25 °C temperature and pressure up to 15 bar.
Graphical Abstract