bluuebunny/crossref_metadata_2025_split huggingface dataset:
The black-legged tick Ixodes scapularis detects CO2 without the Haller's organ
Authors: Städele Carola 
Published: February 2024

ABSTRACT
Both male and female ticks have a strong innate drive to find and blood-feed on hosts. Carbon dioxide (CO2) is considered a critical behavioral activator and attractant for ticks and an essential sensory cue to find hosts. Yet, how CO2 activates and promotes host seeking in ticks is poorly understood. CO2 responses were studied in the black-legged tick Ixodes scapularis, the primary vector for Lyme disease in North America. Adult males and females were exposed to 1%, 2%, 4% or 8% CO2, and changes in walking behavior and foreleg movement were analyzed. CO2 is a potent stimulant for adult I. scapularis, even at lower concentrations (1%). Behavioral reactions depended on the animal's state: walking ticks increased their walking speed, while stationary ticks started to wave their forelegs and began to quest – both behaviors resembling aspects of host seeking. Only in sporadic cases did stationary animals start to walk when exposed to CO2, supporting the hypothesis that CO2 acts as an activator rather than an attractant. Furthermore, I. scapularis did not show a clear concentration preference and was not tuned more robustly to breath-like CO2 concentrations (∼4%) than to the other concentrations tested. Moreover, convincing evidence is provided showing that the foreleg Haller's organ is not necessary for CO2 detection. Even with a disabled or amputated Haller's organ, I. scapularis responded robustly to CO2, signifying that there must be CO2-sensitive structures important for tick host seeking that have not yet been identified.
Fantastic beasts and how to study them: rethinking experimental animal behavior
Authors: Ding Siyu Serena , Fox Jessica L. , Gordus Andrew , Joshi Abhilasha , Liao James C. , Scholz Monika 
Published: February 2024

ABSTRACT
Humans have been trying to understand animal behavior at least since recorded history. Recent rapid development of new technologies has allowed us to make significant progress in understanding the physiological and molecular mechanisms underlying behavior, a key goal of neuroethology. However, there is a tradeoff when studying animal behavior and its underlying biological mechanisms: common behavior protocols in the laboratory are designed to be replicable and controlled, but they often fail to encompass the variability and breadth of natural behavior. This Commentary proposes a framework of 10 key questions that aim to guide researchers in incorporating a rich natural context into their experimental design or in choosing a new animal study system. The 10 questions cover overarching experimental considerations that can provide a template for interspecies comparisons, enable us to develop studies in new model organisms and unlock new experiments in our quest to understand behavior.
Impact of Metastatic Lymph Nodes on Survival of Patients with pN1-Category Esophageal Squamous Cell Carcinoma: A Long-Term Survival Analysis
Authors: Li Kexun , Du Kunyi , Li Changding , He Wenwu , Lu Simiao , Liu Kun , Wang Chenghao , Nie Xin , Han Yongtao , Huang Yunchao , Wang Qifeng , Peng Lin , Leng Xuefeng 
Published: February 2024

Abstract
Background
The morbidity and mortality rates of esophageal squamous cell carcinoma (ESCC) are high in China. The overall survival (OS) of patients with ESCC is related to lymph node (LN) metastasis (LNM). This study aimed to discuss the impact of metastasis in LN stations on the OS of patients with pathologic N1 (pN1) ESCC.

Methods
Data were obtained from the Esophageal Cancer Case Management database of Sichuan Cancer Hospital and Institute (SCCH-ECCM). Additionally, data of patients with pN1-category ESCC collected between January 2010 and December 2017 were retrospectively analyzed.

Results
Data from 807 patients were analyzed. The median OS of the patients with one metastatic LN (group 1) was 49.8 months (95 % confidence interval [CI], 30.8–68.9 months), whereas the OS of those with two metastatic LNs (group 2) was only 33.3 months (P = 0.0001). Moreover, group 1 did not show a significantly longer OS than group 2.1 (patients with 2 metastatic LNs in 1 LNM station; P = 0.5736), but did show a significantly longer OS than group 2.2 (patients with 2 metastatic LNs in 2 LNM stations; P < 0.0001). After propensity score-matching, the 5-year survival rate for group 1 was 28 %, whereas that for group 2 was 14 % (P = 0.0027).

Conclusions
The OS for the patients with one metastatic LN in one LNM was not significantly longer than for the patients with two metastatic LNs in one LNM station. Patients with one LNM station had a significantly longer OS than those with two LNM stations. Thus, the number of LNM stations is a significant determinant of OS in pN1 ESCC.
Long-Term Outcome of Proximal Gastrectomy for Upper-Third Advanced Gastric and Siewert Type II Esophagogastric Junction Cancer Compared With Total Gastrectomy: A Propensity Score-Matched Analysis
Authors: Lee Seungho , Chae Yoon Soo , Yun Won-Gun , Kim Jane Chungyoon , Park Jae Kyun , Kim Min Gyu , Kim Jeesun , Cho Yo-Seok , Kong Seong-Ho , Park Do Joong , Lee Hyuk-Joon , Yang Han-Kwang 
Published: February 2024

Abstract
Background
This study aimed to investigate the oncologic long-term safety of proximal gastrectomy for upper-third advanced gastric cancer (AGC) and Siewert type II esophagogastric junction (EGJ) cancer.

Methods
The study enrolled patients who underwent proximal gastrectomy (PG) or total gastrectomy (TG) with standard lymph node (LN) dissection for pathologically proven upper-third AGC and EGJ cancers between January 2007 and December 2018. Propensity score-matching with a 1:1 ratio was performed to reduce the influence of confounding variables such as age, sex, tumor size, T stage, N stage, and tumor-node-metastasis (TNM) stage. Kaplan-Meier survival analysis was performed to analyze oncologic outcome. The prognostic factors of recurrence-free survival (RFS) were analyzed using the Cox proportional hazard analysis.

Results
Of the 713 enrolled patients in this study, 60 received PG and 653 received TG. Propensity score-matching yielded 60 patients for each group. The overall survival rates were 61.7 % in the PG group and 68.3 % in the TG group (p = 0.676). The RFS was 86.7 % in the PG group and 83.3 % in the TG group (p = 0.634). The PG group showed eight recurrences (1 anastomosis site, 1 paraaortic LN, 1 liver, 1 spleen, 1 lung, 1 splenic hilar LN, and 2 remnant stomachs). In the multivariate analysis, the operation method was not identified as a prognostic factor of tumor recurrence.

Conclusion
The patients who underwent PG had a long-term oncologic outcome similar to that for the patients who underwent TG for upper-third AGC and EGJ cancer.
Mispricing and Algorithm Trading
Authors: Zhang Lihong , Zhang Xiaoquan (Michael) 
Published: February 2024

This study relaxes the efficient market hypothesis by introducing a model that accounts for initial mispricing and explores the effects of algorithmic trading. The research finds that algorithmic strategies can cause significant market volatility and affect financial stability, particularly when they amplify overpricing, leading to bubbles and crashes. Key insights include: Initial mispricing is crucial for algorithmic trading to impact market prices. Market reactions vary with the direction of the trading strategy relative to the asset’s true value. Informed traders can benefit from mispricing, whereas noise traders typically incur losses. Policy implications suggest that algorithmic trading is not universally harmful; its effects depend on the alignment of trading strategies with accurate pricing. The study advises regulators to differentiate between stabilizing and destabilizing trading practices. For traders, the research highlights the importance of adaptive strategies that help correct mispricing to ensure long-term profitability and market health. This research advances our understanding of algorithmic trading’s dual potential and informs the development of more nuanced financial regulations and trading strategies.
RANKL, OPG, and RUNX2 expression and epigenetic modifications in giant cell tumour of bone in 32 patients
Authors: Amri Raja , Chelly Ameni , Ayedi Mariem , Rebaii Mohammed A. , Aifa Sami , Masmoudi Sabeur , Keskes Hassib 
Published: February 2024

AimsThe present study investigated receptor activator of nuclear factor kappa-Β ligand (RANKL), osteoprotegerin (OPG), and Runt-related transcription factor 2 (RUNX2) gene expressions in giant cell tumour of bone (GCTB) patients in relationship with tumour recurrence. We also aimed to investigate the influence of CpG methylation on the transcriptional levels of RANKL and OPG.MethodsA total of 32 GCTB tissue samples were analyzed, and the expression of RANKL, OPG, and RUNX2 was evaluated by quantitative polymerase chain reaction (qPCR). The methylation status of RANKL and OPG was also evaluated by quantitative methylation-specific polymerase chain reaction (qMSP).ResultsWe found that RANKL and RUNX2 gene expression was upregulated more in recurrent than in non-recurrent GCTB tissues, while OPG gene expression was downregulated more in recurrent than in non-recurrent GCTB tissues. Additionally, we proved that changes in DNA methylation contribute to upregulating the expression of RANKL and downregulating the expression of OPG, which are critical for bone homeostasis and GCTB development.ConclusionOur results suggest that the overexpression of RANKL/RUNX2 and the lower expression of OPG are associated with recurrence in GCTB patients.Cite this article: Bone Joint Res 2024;13(2):84–91.
Pandemedia: How COVID Changed Journalism, Tracey Kirkland and Gavin Fang (eds) (2023)
Authors: Bonfiglioli Catriona 
Published: February 2024

Review of: Pandemedia: How COVID Changed Journalism, Tracey Kirkland and Gavin Fang (eds) (2023)
Clayton: Monash University Publishing, 320 pp.,
ISBN 978-1-92263-381-1, p/bk, USD 34.99
The Ten Rules of Reporting, Alan Sunderland (2022)
Authors: Murray Richard 
Published: February 2024

Review of: The Ten Rules of Reporting, Alan Sunderland (2022)
Cammeray: Simon & Schuster Australia, 160 pp.,
ISBN 978-1-76110-823-5, p/bk, AUD 24.99
ISBN 978-1-76110-824-2, e-book, AUD 14.99
Who Needs the ABC? Why Taking It for Granted Is No Longer an Option (2022), Matthew Ricketson and Patrick Mullins
Authors: Murray Richard 
Published: February 2024

Review of: Who Needs the ABC? Why Taking It for Granted Is No Longer an Option (2022), Matthew Ricketson and Patrick Mullins
Brunswick: Scribe Books, 256 pp.,
ISBN 978-1-92231-092-7, p/bk, AUD 29.99
ISBN 978-1-92258-649-0, e-book, AUD 16.43
Seeking Truth in International TV News: China, CGTN and the BBC, Vivien Marsh (2023)
Authors: Josephi Beate 
Published: February 2024

Review of: Seeking Truth in International TV News: China, CGTN and the BBC, Vivien Marsh (2023)
Abingdon: Routledge, 232 pp.,
ISBN 978-0-36755-852-9, h/bk, USD 226.80
ISBN 978-1-00309-543-9, e-book, USD 63.90
Challenges in Connecting The Elements of Sectoral System of Innovation for Developing Electric Vehicle Industry in Indonesia
Authors: Ariyani Luthfina , Dinaseviani Anggini , Rosadi Asep Husni Yasin , Febrianda Rendi , Hermawati Wati , Aminullah Erman 
Published: February 2024

<p>This article discusses industrial development on EV di Indonesia, viewed from<strong> </strong>Sectoral system of innovation (SSI) perspective. The objective of this study is to map challenges in connecting the elements of SSI for developing EV industry. The method of study is a desk research, where the information input relies on secondary sources, consisting of statistical data, official documents and scientific references. This study found eight challenges to develop EV industry. The institutional challenges include: i. fiscal programs are still less effective to promote industrial collaboration on EV innovation with universities and R&amp;D institutions; ii. Local content target is still difficult to fulfill; iii. unreadiness of local industry to be involved in the EV supply chain; and iv. Slow consumer response towards EV program incentives. On the knowledge and technology challenges are: i) the quality and standards of EVs from domestic R&amp;D are still inadequate for commercial scale; and ii. potential investors have not shown adequate interest in local EV development. The demand challenges are: i. the plan to make Indonesia as EV hub in ASEAN region is far from reality due to lack of investors; and ii. the lack of ECS accessibility is a barrier to the domestic EV market.</p><p> </p>Keywords: electric vehicle, sectoral system of innovation, institutions, knowledge and technology, demand
A Mapping Outcome Method Using Social Return on Investment (SROI) to Assess the Impacts of Program: A Case Study in Setunak Island
Authors: Suryani Retno , Budi Susilo Nugroho , Desta Ode Arinal , Silfiana Andriani , Wulansari Rina , Sila Puspita Annisa 
Published: February 2024

Climate change as a global phenomenon is inevitable, including in Indonesia. Its impacts include rising sea levels, expanding coral bleaching, and declining coastal ecosystems, particularly mangrove forests and coral reefs. Many research explores the characteristics of vulnerability to climate change in coastal cities and seeks feasible adaptation options for these cities with method used involved surveys of residents, interviews with experts, and statistical analysis and modeling. Although efforts have been made to prevent climate change, there is still a lack of research that explores the broader impacts of these efforts. In this regard, few studies have measured the social, economic, or environmental value that arises from these efforts. This study aims to evaluate, measure, and assess the impacts that have occurred as a result of the implementation of the program from environmental, economic, welfare, and social perspectives comprehensively. The result show that the SROI study results indicate that the Pulau Tahan program has positive economic, social, and environmental impacts. However, the on-field study also found a less positive fact regarding the availability of crab seedlings.
Stakeholder Pressure and Its Effect on Sustainability Report
Authors: Wahyuningrum Indah Fajarini Sri , Ihlashul’amal Muhammad , Hidayah Retnoningrum , Widhi Rizkyana Fitrarena 
Published: February 2024

The quality of corporate sustainability reports in Indonesia is unfortunately found to be lacking, with a rating of only 53.6%. This is significantly lower compared to the average of other Southeast Asian countries. However, stakeholders are becoming more aware of their role in encouraging public companies to disclose sustainability information. This study intends to look at the quality of sustainability reports released by Indonesian public firms, as well as the impact of stakeholder pressure on these reports' quality. Data from annual and sustainability reports of businesses listed on the Indonesia Stock Exchange between 2016 and 2020 are used in the research, which is based on GRI's G4 guidelines and the GRI Standards 2016. The study looks at numerous stakeholder pressures, including pressure from creditors, media exposure, the Big Four accounting firms, employees, consumers, environmentally sensitive industries, and shareholders. The results show that companies with significant media coverage typically produce sustainability reports of high quality. However, pressure from other stakeholders has not been found to have a significant impact on the quality of these reports. This study provides valuable insights into the state of sustainability reporting in Indonesia and aims to encourage stakeholders to actively participate in promoting a sustainable industry.
Variations in tumor growth, intra-individual biological variability, and the interpretation of changes
Authors: Trapé Jaume , Bérgamo Silvia , González-Fernández Carolina , Rives José , González-García Laura 
Published: February 2024

Abstract

Objectives
The identification of changes in tumor markers (TMs) in cancer patients that indicate response to treatment, stabilization or disease progression is a challenge for laboratory medicine. Several approaches have been proposed: assessing percentage increases, applying discriminant values, and estimating half-life (t1/2) or doubling time (DT). In all of them it is assumed that the TM is a surrogate of the variation in tumor size. In general this variation is time-dependent, but this is not the case of intraindividual biological variability (CVi), which can range from 6 % in CA15-3 to 22 % in CA125. When decisions are made on the basis of DT or t1/2, these values can be affected by the CVi; if it is very large, the growth rate very slow and the period of time between determinations very short, the result obtained for DT may be due mainly to the CVi. The aim of this study is to establish the relationship between the CVi and temporal variables.

Methods
We related equations for calculating DT and t1/2 to the reference change values in tumor markers.

Results
The application of the formula obtained allows the calculation of the optimal time between measurements to ensure that the influence of the CVi is minimal in different types of tumors and different scenarios.

Conclusions
Intraindividual variation affects the calculation of DT and t1/2. It is necessary to establish the minimum time between two measurements to ensure that the CVi does not affect their calculation or lead to misinterpretation.
Hybrid optimization strategy for water cooling system: enhancement of photovoltaic panels performance
Authors: Singh Vijay Pal , Arya Sandeep Kumar , Shankar Ajay 
Published: February 2024

Abstract
Solar energy is the most effective substitute for fossil fuels when it comes to Produce electricity among the numerous renewable energy sources. The efficiency may drop as a result of overheating, and the PV cell may also be harmed. Therefore, increasing the output of a solar PV system at a lower cost is essential to improving its efficiency. Additionally, by using cooling methods, the PV cells’ lifetime is extended. By lowering the working temperature of a PV panel’s surface, you may increase efficiency and slow the thermal deterioration rate. This may be done by module cooling and lowering the heat that the PV cells generate while operating. Hence, an active cooling technology known as optimization-aided water spraying technique is employed to increase efficiency. This method enables the PV panels to provide their maximum output power while taking less time to drop down to a lower surface temperature. Beluga Whale assisted Jellyfish Optimization (BWJO) model is suggested as a means of achieving these goals. Finally, Simulink/MATLAB is used to implement the suggested method and optimize the PV system cooling. The performances of the two components were compared using a variety of metrics.
The (Vi)Kings’ Saga: Mixed Modality as the Key to the Construction of Meaning in Jómsvíkinga saga
Authors: Korecká Lucie 
Published: February 2024

Abstract
The objective of this article is to analyse the narrative functions of mixed modality in Jómsvíkinga saga, a text that combines elements of different saga genres, primarily the kings’ sagas and the legendary sagas. It is argued here that the mixed modality is not a sign of the early saga’s imperfection, but it serves as a narrative device that contributes to the saga’s capacity to indirectly express commentary on social issues that were current at the time of the saga’s composition.
Crash performance of a novel bio-inspired energy absorber produced by additive manufacturing using PLA and ABS materials
Authors: Erdaş Mehmet Umut , Yildiz Betül Sultan , Yildiz Ali Rıza 
Published: February 2024

Abstract
Thin-walled structures are one of the important safety components used in vehicles. They are placed in the front parts of the vehicles to minimize the impacts that occur in the event of a collision, and they absorb the impact force by changing shape in the event of a collision. Crash boxes have high-impact absorption, low weight, and low-cost expectations. In the design of crash boxes, thin-walled structures are preferred due to their high deformation capability. In this study, the additive manufacturing method was used to produce thin-walled structures. Thin-walled structures were produced by additive manufacturing methods using PLA and ABS materials. The manufactured crash boxes were tested using an impact test. In the experimental results, the energy absorption ability of the crash boxes produced from PLA and ABS materials was examined, and high fragility was observed. The experimental results were verified by finite element analysis of the crash boxes made using PLA and ABS materials.
The crystal structure of [hexaaquamagnesium(II)] 4-[(pyridine-4-carbonyl)-amino]-phthalate trihydrate, C14H26N2O14Mg
Authors: Fan-Yuan Kong , Xiang-Yan Kong , Xiao-Ru Pan , Xi-Shi Tai 
Published: February 2024

Abstract
C14H26N2O14Mg, triclinic, P

1
‾

$\overline{1}$

(no. 2), a = 7.0646(2) Å, b = 8.5008(2) Å, c = 17.2402(2) Å, α = 86.230(2)°, β = 81.415(2)°, γ = 82.768(2)°, V = 1014.45(4) Å3, Z = 2, Rgt
(F) = 0.0340, wRref
(F
2) = 0.0904, T = 216(40) K.
Crystal structure of 1-(p-tolylphenyl)-4-(2-furoyl)-3-methyl-1H-pyrazol-5-ol, C16H14N2O3
Authors: Wu Qiong , Huang Zhen-Yu , Liu Yun-Xin , Zhang Heng-Qiang , Jin Tong-Yin , Xue Yu-Na , Liu Chang 
Published: February 2024

Abstract
C16H14N2O3, monoclinic, P21/n (no. 14), a = 4.9621(10) Å, b = 11.828(2) Å, c = 23.727(5) Å, β = 94.527(4)°, V = 1388.2(5) Å3, Z = 4, R

gt
(F) = 0.0551, wR

ref
(F
2) = 0.1847, T = 296(2) K.
The crystal structure of tris(tetra-n-butylammonium) hexanitrato-κ2O,O′-lanthanium(III) C48H108N9O18La
Authors: Xi-Shi Tai 
Published: February 2024

Abstract
C48H108N9O18La, monoclinic, P21/n (no. 14), a = 16.5000(10) Å, b = 22.5924(14) Å, c = 17.4287(10) Å, β = 90.875(5)°, V = 6496.2(7) Å3, Z = 4, Rgt
(F) = 0.0716, wRref
(F
2) = 0.1706, T = 100 K.
The effects of synthetic and physical factors on the properties of poly(acrylic acid)-based hydrogels synthesized by precipitation polymerization technique: a review
Authors: Farqarazi Sahar , Khorasani Manouchehr 
Published: February 2024

Abstract
The polymer obtained from hydrophilic monomers can be transformed into a hydrogel via cross-linking by different cross-linkers. Hydrogels are three-dimensional networks that can absorb several times their weight and swell in water/swelling media, improving the media’s viscosity as a thickener. The cross-linked poly(acrylic acid) microparticles prepared via precipitation polymerization technique are often synthesized by radical polymerization and have carboxylic functional groups in their structure, which make the hydrogel properties such as swelling capacity, particle morphology, and viscosity be controlled by physical factors such as solvent, neutralizer, pH, pK

a
, zeta potential, and ionic strength of the swelling media, as well as synthetic factors including comonomer, cross-linker, and network type. In this paper, the effects of crucial factors on the synthetic and swelling steps are elaborated to facilitate the achievement of poly(acrylic acid)-based xerogels having desirable rheological properties, such as swelling/viscosity optimization, which is the primary purpose of a thickener in any swelling media.