bluuebunny/crossref_metadata_2025_split huggingface dataset:
Splenic stromal sarcomas in dogs: Outcome and clinicopathological prognostic factors in 32 cases
Authors: Ferrari Roberta , Marconato Laura , Boracchi Patrizia , Stefanello Damiano , Godizzi Francesco , Murgia Daniela , Schievenin Valentina , Amati Maria , Faroni Eugenio , Roccabianca Paola 
Published: November 2023

AbstractDue to the low frequency and the changes in diagnostic techniques and terminology during the last few years, only little clinical information is available on splenic stromal sarcoma (SSS). This multi‐institutional study aimed at gathering clinical cases of SSS in dogs and investigates their clinical behaviour, as well as analyse possible clinicopathological prognostic factors, including the use of adjuvant therapy. Dogs with a histologically confirmed SSS that underwent splenectomy were retrospectively included. To be included in the study, either FFPE tissue blocks or multiple tissue sections had to be available for histopathologic and immunohistochemical revision. Clinical and pathological variables, along with adjuvant therapy data, were collected. Cumulative incidence of metastatic disease was analysed through univariate and bivariate analyses. The impact of adjuvant chemotherapy on metastasis incidence and survival was assessed, considering an estimated propensity score. A total of 32 dogs were included. Among them, 22 developed metastases with an incidence of 37.5%, 59.38%, and 65.94% at 6, 12, and 24 months, respectively. Univariate analysis identified mitotic count, total scoring, and necrosis as prognostic factors. In bivariate analysis, mitotic count remained prognostic. The administration of adjuvant chemotherapy did not have an impact on metastasis incidence or survival time. The study found that dogs with SSSs are at high risk of metastasis, although a small subgroup may experience longer survival after splenectomy. Mitotic count was the only variable having a reliable prognostic impact. Adjuvant chemotherapy did not appear to decrease the incidence of metastasis or prolong survival in these dogs.
Theoretical and Experimental Investigation of Material Removal Rate in Magnetorheological Shear Thickening Polishing of Ti–6Al–4V Alloy
Authors: Tian Yebing , Ma Zhen , Ahmad Shadab , Qian Cheng , Ma Xifeng , Yuan Xiangyu , Fan Zenghua 
Published: November 2023

Abstract
Magnetorheological shear thickening polishing (MRSTP) is a novel hybrid polishing method that combines the magnetorheological effect and the shear thickening effect. It has great potential for ultra-precision machining of complex surfaces. However, the absence of a correlation between material removal and the rheological properties of the polishing media has posed difficulties for further improvements in polishing efficiency and quality in MRSTP. In this work, a material removal model for MRSTP was established based on the principles of magneto-hydrodynamics, non-Newtonian fluid kinematics, and microscopic contact mechanics. This model combines the material removal model for a single abrasive particle with a statistical model of active grits. When comparing the experimental and theoretical results, it became evident that the developed material removal model can accurately predict the material removal depth of the workpiece under different processing parameters such as rotational speed of the rotary table and magnetic field strength. The average prediction error was found to be less than 5.0%. Furthermore, the analysis of the rheological behavior and fluid dynamic pressure of the polishing media reveals the coupling effects between the magnetic, stress, and flow fields. This provides theoretical guidance for the actual processing of MRSTP. Finally, the maximum material removal rate of 3.3 μm/h was achieved on the cylindrical surface of the Ti–6Al–4V workpiece using the MRSTP method. These results demonstrate that the MRSTP method holds great potential in the field of ultra-precision machining of difficult-to-machine materials.
Paediatric intensive care admissions of preterm children born <32 weeks gestation: a national retrospective cohort study using data linkage
Authors: van Hasselt Tim J , Gale Chris , Battersby Cheryl , Davis Peter J , Draper Elizabeth , Seaton Sarah E 
Published: November 2023

ObjectiveSurvival of babies born very preterm (<32 weeks gestational age) has increased, although preterm-born children may have ongoing morbidity. We aimed to investigate the risk of admission to paediatric intensive care units (PICUs) of children born very preterm following discharge home from neonatal care.DesignRetrospective cohort study, using data linkage of National Neonatal Research Database and the Paediatric Intensive Care Audit Network datasets.SettingAll neonatal units and PICUs in England and Wales.PatientsChildren born very preterm between 1 January 2013 and 31 December 2018 and admitted to neonatal units.Main outcome measuresAdmission to PICU after discharge home from neonatal care, before 2 years of age.ResultsOf the 40 690 children discharged home from neonatal care, there were 2308 children (5.7%) with at least one admission to PICU after discharge. Of these children, there were 1901 whose first PICU admission after discharge was unplanned.The percentage of children with unplanned PICU admission varied by gestation, from 10.2% of children born <24 weeks to 3.3% born at 31 weeks.Following adjustment, unplanned PICU admission was associated with lower gestation, male sex (adjusted OR (aOR) 0.79), bronchopulmonary dysplasia (aOR 1.37), necrotising enterocolitis requiring surgery (aOR 1.39) and brain injury (aOR 1.42). For each week of increased gestation, the aOR was 0.90.ConclusionsMost babies born <32 weeks and discharged home from neonatal care do not require PICU admission in the first 2 years. The odds of unplanned admissions to PICU were greater in the most preterm and those with significant neonatal morbidity.
Deep-learning-based prediction of glaucoma conversion in normotensive glaucoma suspects
Authors: Ha Ahnul , Sun Sukkyu , Kim Young Kook , Jeoung Jin Wook , Kim Hee Chan , Park Ki Ho 
Published: November 2023

Background/aims
To assess the performance of deep-learning (DL) models for prediction of conversion to normal-tension glaucoma (NTG) in normotensive glaucoma suspect (GS) patients.

Methods
Datasets of 12 458 GS eyes were reviewed. Two hundred and ten eyes (105 eyes showing NTG conversion and 105 without conversion), followed up for a minimum of 7 years during which intraocular pressure (IOP) was lower than 21 mm Hg, were included. The features of two fundus images (optic disc photography and red-free retinal nerve fibre layer (RNFL) photography) were extracted by convolutional auto encoder. The extracted features as well as 15 clinical features including age, sex, IOP, spherical equivalent, central corneal thickness, axial length, average circumpapillary RNFL thickness, systolic/diastolic blood pressure and body mass index were used to predict NTG conversion. Prediction was performed using three machine-learning classifiers (ie, XGBoost, Random Forest, Gradient Boosting) with different feature combinations.

Results
All three algorithms achieved high diagnostic accuracy for NTG conversion prediction. The AUCs ranged from 0.987 (95% CI 0.978 to 1.000; Random Forest trained with both fundus images and clinical features) and 0.994 (95% CI 0.984 to 1.000; XGBoost trained with both fundus images and clinical features). XGBoost showed the best prediction performance for time to NTG conversion (mean squared error, 2.24). The top three important clinical features for time-to-conversion prediction were baseline IOP, diastolic blood pressure and average circumpapillary RNFL thickness.

Conclusion
DL models, trained with both fundus images and clinical data, showed the potential to predict whether and when normotensive GS patients will show conversion to NTG.
Association between intraprocedural drops in blood pressure and infarct growth rate patterns after acute large-vessel occlusions
Authors: Galecio-Castillo Milagros , Quispe-Orozco Darko , Farooqui Mudassir , Dajles Andres , Vivanco-Suarez Juan , Rodriguez-Calienes Aaron , Prasad Ayush , Begunova Liza , Petersen Nils H , Ortega-Gutierrez Santiago 
Published: November 2023

Background
Infarct growth rate (IGR) differs among patients with acute ischemic stroke due to large vessel occlusion (LVO-AIS), and this variability has critical clinical repercussions. We explored IGR patterns and their association with blood pressure during endovascular therapy (EVT).

Methods

This is a two-center cohort observational study that included consecutive anterior circulation LVO-AIS patients who underwent EVT and achieved modified Thrombolysis in Cerebral Infarction (mTICI) 2 c-3. Initial and final infarct volumes (FIV) were defined using admission computed tomography perfusion (CTP) defined as relative cerebral blood flow (rCBF) <30%, and diffusion-weighted imaging-magnetic resonance imaging (DWI-MRI) at 24 hours post-EVT. We categorized IGR patterns as exponential (ExpIGR) and Non-exponential (NonExp) based on their growth curves. We then dichotomized ExpIGR clinical significance based on the association of infarct growth with 90-day Modified Rankin Score (mRS) as ExpIGR-A (
>
13 mL) and ExpIGR-B (<13 mL). Intraprocedural blood pressure (BP) drops were calculated as the difference between median arterial pressure (MAP) at admission and the lowest intraprocedural MAP reading before recanalization, and the area between admission MAP threshold and all lower measurements of intraprocedural MAP. Logistic and linear regression were used to investigate associations between variables of interest.

Results
Of 159 modified Thrombolysis in Cerebral Infarction (mTICI) 2 c-3 patients, we found that 36% demonstrated ExpIGR-A, 31% ExpIGR-B, and 32.7% NonExp patterns. The Exp-A and Exp-B groups differed significantly in National Institutes of Health Stroke Scale (NIHSS) score, Alberta Stroke Program Early CT Score (ASPECTS), glucose, and FIV. The Exp-A and NonExp groups differed in rCBF <30% vol, and time of stroke onset (SO) to admission CTP; and the Exp-B and NonExp groups in NIHSS, rCBF <30%, Tmax <6 s volume, collateral flow measured by hypoperfusion intensity ratio (HIR), and FIV. Hypotensive MAP area (HMA) was independently associated with an ExpIGR-A pattern. Infarct volume increased by 1 mL per 100 units of hypotensive area and 4.2 mL per 0.1 units of HIR, with a significant interaction between both variables.

Conclusion
After an LVO-AIS, the IGR can be differentiated into two distinct exponential and non-exponential patterns. A subgroup of patients with the exponential pattern experienced clinically meaningful infarct growth rates between CTP acquisition and reperfusion and seem to be highly vulnerable to episodes of sustained intraprocedural BP drops during EVT.
Measurement of the $$\gamma n\rightarrow K^0\Sigma ^0$$ differential cross section over the $$K^*$$ threshold
Authors:   BGOOD Collaboration, Kohl K. , Jude T. C. , Alef S. , Beck R. , Braghieri A. , Cole P. L. , Elsner D. , Di Salvo R. , Fantini A. , Freyermuth O. , Frommberger F. , Ghio F. , Gridnev A. , Hammann D. , Hannappel J. , Kozlenko N. , Lapik A. , Sandri P. Levi , Lisin V. , Mandaglio G. , Messi R. , Moricciani D. , Nedorezov V. , Nikonov V. A. , Novinskiy D. , Pedroni P. , Polonskiy A. , Reitz B.-E. , Romaniuk M. , Scheluchin G. , Schmieden H. , Stuglev A. , Sumachev V. , Tarakanov V. 
Published: November 2023

AbstractThe differential cross section for the quasi-free photoproduction reaction $$\gamma n\rightarrow K^0\Sigma ^0$$

γ
n
→

K
0

Σ
0

was measured at BGOOD at ELSA from threshold to a centre-of-mass energy of $$2400\,\hbox {MeV}$$

2400

MeV

. Close to threshold the results are consistent with existing data and are in agreement with partial wave analysis solutions over the full measured energy range, with a large coupling to the $$\Delta (1900)1/2^-$$

Δ

(
1900
)

1
/

2
-

evident. This is the first dataset covering the $$K^*$$

K
∗

threshold region, where there are model predictions of dynamically generated vector meson-baryon resonance contributions.
No Effect of Continued Antiarrhythmic Drug Treatment on Top of Optimized Pulmonary Vein Isolation in Patients With Persistent Atrial Fibrillation: Results From the POWDER-AF2 Trial
Authors: Demolder Anthony , O’Neill Louisa , El Haddad Milad , Scherr Daniel , Vijgen Johan , Wolf Michael , Berte Benjamin , Bisbal Felipe , Johannessen Arne , Rivero-Ayerza Maximo , De Potter Tom , De Becker Benjamin , Polain de Waroux Jean-Benoît le , Knecht Sebastien , Tavernier Rene , Duytschaever Mattias 
Published: November 2023

BACKGROUND:
In patients with persistent atrial fibrillation (PersAF), catheter ablation aiming for pulmonary vein isolation (PVI) is associated with moderate clinical effectiveness. We investigated the benefit of continuing previously ineffective class 1C or 3 antiarrhythmic drug therapy (ADT) in the setting of a standardized PVI-only ablation strategy.

METHODS:
In this multicenter, randomized controlled study, patients with PersAF (≥7 days and <12 months) despite ADT were prospectively randomized 1:1 to PVI with ADT continued versus discontinued beyond the blanking period (ADT ON versus ADT OFF). Standardized catheter ablation was performed aiming for durable isolation with stable, contiguous, and optimized radio frequency applications encircling the pulmonary veins (CLOSE protocol). Clinical visits and 1-to-7-day Holter were performed at 3, 6, and 12 months. The primary end point was any documented atrial tachyarrhythmia lasting >30 seconds beyond 3 months. Prospectively defined secondary end points included repeat ablations, unscheduled arrhythmia-related visits, and quality of life among groups.

RESULTS:
Of 200 PersAF patients, 98 were assigned to ADT OFF and 102 to ADT ON. The longest atrial fibrillation episode qualifying for PersAF was 28 (10–90) versus 30 (11–90) days. Clinical characteristics and procedural characteristics were similar. Recurrence of atrial tachyarrhythmia was comparable in both groups (20% OFF versus 21.2% ON). No differences were observed in repeat ablations and unscheduled arrhythmia-related visits. Marked improvement in quality of life was observed in both groups.

CONCLUSIONS:
In patients with PersAF, there is no benefit in continuing previously ineffective ADT beyond the blanking period after catheter ablation. The high success rate of PVI-only might be explained by the high rate of durable isolation after optimized PVI and the early stage of PersAF (POWDER-AF2).

REGISTRATION:

URL:
https://www.clinicaltrials.gov
; Unique identifier: NCT03437356.
At What Cost? Is Technical Education Worth the Investment?
Authors: Dougherty Shaun M. , Smith Mary M. 
Published: November 2023

Abstract
Career and technical education (CTE) has existed in the United States for over a century, and only in recent years have there been opportunities to assess the causal impact of participating in these programs while in high school. To date, no work has assessed whether the relative costs of these programs meet or exceed the benefits as described in recent evaluations. In this paper, we use available cost data to compare average costs per pupil in standalone high school CTE programs in Connecticut and Massachusetts to the most likely counterfactual schools. Under a variety of conservative assumptions about the monetary value of known educational and social benefits, we find that programs in Massachusetts offer clear positive returns on investment, whereas programs in Connecticut offer smaller, though mostly non-negative expected returns. We also consider the potential cost effectiveness of CTE programs offered in other contexts to address questions of generalizability.
Money, Morality, and Modernity: A Javanese Remake of a 1930 American Whodunnit in 1960s Indonesia
Authors: Wieringa E.P. 
Published: November 2023

Abstract
Suparto Brata (1932–2015) belongs to the pioneers of the Western model of the whodunnit in modern Javanese literature. His early (1962) work Pethité Njai Blorong (The Tail of Nyai Blorong) is a remake of the 1930 whodunnit While the Patient Slept by the US crime novelist Mignon G. Eberhart (1899–1996), which is a murder mystery in true Agatha Christie fashion. This article shows how Suparto Brata did not simply reproduce Eberhart’s detective story in a postcolonial Indonesian setting but thoroughly and successfully reworked it until it hardly resembled its prototype anymore, turning a foreign example into a veritable modernist Javanese kind of Bildungsroman that mirrored 1960s Indonesian societal issues under the shadow of Sukarno’s nationalist policies and catastrophic economic conditions.
Proxy Observations of Surface Wind from a Globally Distributed Network of Wave Buoys
Authors: Dorsay Ciara , Egan Galen , Houghton Isabel , Hegermiller Christie , Smit Pieter B. 
Published: November 2023

Abstract
In the equilibrium range of the wave spectrum’s high-frequency tail, energy levels are proportional to the wind friction velocity. As a consequence of this intrinsic coupling, spectral tail energy levels can be used as proxy observations of surface stress and wind speed when direct observations are unavailable. Proxy observations from drifting wave-buoy networks can therefore augment existing remote sensing capabilities by providing long dwell observations of surface winds. Here we consider the skill of proxy wind estimates obtained from observations recorded by the globally distributed Sofar Spotter network (observations from 2021 to 2022) when compared with collocated observations derived from satellites (yielding over 20 000 collocations) and reanalysis data. We consider physics-motivated parameterizations (based on frequency−4 universal tail assumption), inverse modeling (estimate wind speed from spectral energy balance), and a data-driven approach (artificial neural network) as potential methods. Evaluation of trained/calibrated models on unseen test data reveals comparable performance across methods with generally of order 1 m s−1 root-mean-square difference with satellite observations.
Extracorporeal Membrane Oxygenation During Surgical Stabilization of Rib Fractures in Successful Management of Severe Blunt Chest Trauma
Authors: Jensen Stephanie , Dabagian Hannah Olson , Porter Kierstin , Thomas Bradley , Dieffenbaugher Sean , Cunningham Kyle , Green John , Ross Samuel W. , Sachdev Gaurav 
Published: November 2023

Early surgical stabilization of rib fracture (SSRF) improves outcomes in patients with flail physiology and severely displaced fractures. We present two cases of patients with severe chest injury and large flail segment who underwent SSRF while on veno-venous extracorporeal membrane oxygenation (VV-ECMO). The patients developed respiratory failure within 24 hours of admission requiring VV-ECMO. The extent of their chest wall injury limited pulmonary mechanics prohibiting transition off VV-ECMO. Therefore, SSRF was performed on hospital days 2 and 3 and while on VV-ECMO support. Stabilizing the chest wall allowed for improved ventilation and successful decannulation from VV-ECMO on postoperative days 3 and 4. Ultimately, both achieved a functional recovery and were discharged home. These cases demonstrate a unique thoracic damage control strategy wherein SSRF is performed while on VV-ECMO. Improving chest stability and pulmonary mechanics with SSRF allowed for safe transition off VV-ECMO and achieved a favorable long-term outcome.
The effects of authoritative source cue and argument strength of correction tweets on MMR vaccine-related misinformation credibility
Authors: Lee Jiyoung , Kang Dayoung , Lee Hee Yun , Kim Ji Won 
Published: November 2023

Objectives: This study aimed to examine the joint effect of two core message elements – authoritative source and argument strength – in correction tweets to counter conspiratorial misinformation about the measles, mumps and rubella (MMR) vaccine. Design/Method: An online experiment with US residents ( N = 404) was conducted in a 2 (authoritative correction sources: layperson vs US Centres for Disease Prevention and Control [CDC]) × 2 (correction argument strength: weak vs strong) design. Results: The results indicate that the correction employing strong arguments and a correction provided by the CDC heightened heuristic processing of the corrective information, which in turn increased the perceived credibility of the conspiratorial misinformation. The effect of the CDC correction on heuristic processing was heightened when it contained weak arguments. Notably, user-generated corrections with weak arguments reduced heuristic processing of the information and contributed to reducing the perceived credibility of the misinformation. Conclusion: Based on the findings, we argue that both communicator- and content-related cues jointly influence how audiences process corrective information. The current study discusses the potency of user-generated social media corrections to counter vaccine misinformation and provides practical implications for how user-generated social media correction can be utilised by health practitioners. Public health organisations should prioritise presenting corrective information in an easily understandable manner, using user-generated content that fosters a sense of connection and engagement with individuals.
Occupational therapy practice to support executive function impairment after acquired brain injury: A UK clinical survey
Authors: de Charentenay Sarah , Whitney Julie , Logan Philippa A 
Published: November 2023

Introduction: This study explored treatment of executive functioning impairment in adults after acquired brain injury (ABI), clinician’s confidence and support received, in a sample of occupational therapists in the United Kingdom. Methods: A 24-item online questionnaire was sent to 750 members of the Royal College of Occupational Therapists Specialist-Section in Neurological Practice. Data was collected at a nominal and ordinal level and included yes/no Likert-type scale and free field comments. Descriptive statistical analysis was completed. Results: Seventy-six occupational therapists working in a range of neurological settings completed the survey. Frequently used interventions included education ( n = 57, 75%), task modification ( n = 56, 73%), instrumental activities of daily living (ADL) ( n = 54, 71%), personal ADL ( n = 53, 70%) and goal setting ( n = 53, 70%). Seventy-one percent used metacognitive strategies. Occupation-based metacognitive approaches were rarely used. Thirty-one (41%) participants reported being fairly confident and 28 (37%) were very confident. Support for clinical practice was accessed most frequently through joint clinical sessions ( n = 30, 39%). Findings: Participants used various clinical interventions to treat service users with executive dysfunction after ABI. Meta-cognitive strategies were employed; however, occupation-based metacognitive approaches were infrequently utilised, suggesting uncertainty in adopting these in practice. The need for further training on evidence-based interventions and knowledge translation support was highlighted.