bluuebunny/crossref_metadata_2025_split huggingface dataset:
Authentic leadership for creativity and innovation: The moderating role of motivating language
Authors: Siswanti Yuni , Muafi Muafi 
Published: January 2025

Orientation: Creativity and innovation are essential in coping with a complex business environment that becomes more complex and rapidly changing.Research purpose: To investigate the impact of an authentic leadership style on employee creativity and innovation behaviour in the workplace, using motivating language as a moderator.Motivation for the study: The study is carried out to fill the existing gaps on creativity and innovation by distinguishing both constructs, within the context of micro, small and medium enterprises (MSMEs) in Indonesia.Research approach/design and method: This study employed a quantitative approach, surveying 350 employees from creative MSMEs in West Java and Central Java, Indonesia. Smart partial least squares (PLS) software analysis was used to analyse the data using a structural equation model for validating the proposed model.Main findings: Authentic leadership positively influences employee creativity and innovative work behaviour in the workplace. In addition, innovative work behaviour is also positively influenced by employee creativity. These positive influences can be strengthened by motivating language from the leader.Practical/managerial implications: Organisations wanting to increase the innovative work behaviour of their employees should select leaders with authentic traits and put them into practice. Interventions to develop leaders’ use of motivating language are required to enable them to encourage the use of their creative ideas.Contribution/value-add: The present study considers how motivating language, which has rarely been examined within the field, can play a significant moderating role in innovative work behaviours.
Acute Poststreptococcal Glomerulonephritis at a Single Center Before and During the Pandemic
Authors: Reyes Lisha Alyanna Atienza , Cabansag Maria Rosario Florentino 
Published: January 2025

Background:
Acute poststreptococcal glomerulonephritis (APSGN) remains an important cause of hospitalization among pediatric patients in low- to middle-income countries. During the pandemic, healthcare delivery faced further challenges, delaying diagnosis and management of childhood illnesses, which may contribute to disease severity. Limited studies explore the state of diagnosis and treatment of APSGN before and during the pandemic.

Objective:
The objective of this study was to compare the demographic, clinical, and laboratory profiles of pediatric patients diagnosed with APSGN before the pandemic (2017–2019) versus during the pandemic (2020–2022) and to determine which factors are associated with length of hospital stay (LOS).

Methodology:
An analytic cross-sectional study was conducted in a local government hospital. Medical charts of 102 patients <18 years old clinically diagnosed with APSGN based on hematuria, edema, hypertension, and/or oliguria admitted from January 2017 to December 2022 were reviewed.

Results:
The mean age of patients was 7 years; 57 (56%) were female. Demographic, clinical manifestation, and laboratory profiles were not significantly different before and during the pandemic (all P > 0.05). The median LOS was 6 days. Elevated blood urea nitrogen (BUN) (adjusted odds ratio [OR] =1.04; P = 0.018) and low C3 level (adjusted OR = 0.97; P = 0.042) were significantly associated with LOS.

Conclusion:
The demographic, clinical, and laboratory profiles of APSGN patients before and during the pandemic were comparable. Elevated BUN and low C3 levels are significantly associated with LOS.
Association of maternal and fetal factors with quality parameters of umbilical cord blood collected from mothers undergoing cesarean section
Authors: Muthu Bharathi , Basavarajegowda Abhishekh , Subbaiah Murali , Manivannan Prabhu 
Published: January 2025

Abstract

INTRODUCTION:
Understanding the association between maternal and fetal factors and the quality parameters of umbilical cord blood (UCB) is essential for optimizing collection and improving outcomes in medical treatments. It helps us to improve the selection of mothers or prospective cord blood donors, thereby improving the quality of the cord blood stem cells. The study aimed to explore how the various fetal and maternal parameters affect the yield and viability of umbilical cord stem cell collection in mothers undergoing cesarean section.

METHODOLOGY:
This was a cross-sectional study wherein cord blood samples were collected from mothers who underwent lower segment cesarean section, and parameters such as CD34 count, viability, and mononuclear cell count were estimated by flow cytometry. The volume was measured. Relevant clinical details of the mothers were collected from the case records. The tests of association between categorical variables and outcome variables were assessed using the Chi-square test. Spearman rank association coefficient was calculated for univariate analyses to ascertain the relationship between continuous variables and outcomes.

RESULTS:
The number of CD34+ cell counts in the UCB correlated positively with the age of the women (Ρ = 0.263; mild positive correlation), gestational age (GA) (Ρ = 0.477; moderate positive correlation), birth weight (Ρ = 0.556; moderate positive correlation), placental weight (Ρ = 0.305; weak positive correlation), and cord length (Ρ = 0.377; weak positive correlation).

CONCLUSION:
Maternal factors such as increased GA, maternal age, prolonged duration of labor, and placental weight have a significant positive effect on CD34+ and total nucleated cell count. Fetal factors that have a favorable effect on count were increased birth weight and meconium-stained liquor.
The effect of remineralization pretreatments on the enamel bond strength of demineralized and sound enamel: An in vitro study
Authors: Shirani Farzaneh , Malekipour Mohammad Reza , Azary Maryam , Manesh Vahid Sakhaei , Gilani Amirali , Mazdak Ali 
Published: January 2025

ABSTRACT

Background:
During tooth preparation, the clinician may face a hard remineralized enamel surrounding the cavity with unknown effects on the enamel bond strength. This study aims to assess the effect of remineralizing pretreatments with casein phosphopeptide-amorphous calcium phosphate (CPP-ACP) or CPP-amorphous calcium fluoride phosphate (CPP-ACFP) on the bond strength of composite resin and sound or demineralized enamel.

Materials and Methods:
This study employed an in vitro experimental factorial design. A total of 144 enamel surfaces were prepared and randomly divided into 12 groups (G1-G12). The surfaces of G7-12 were demineralized to create a lesion (L), while G1-6 were assigned to the sound (S) enamel group. The three pretreatment protocols were CPP-ACFP, CPP-ACP, or no pretreatment for a 10-day pH-cycling period. A composite rod was bonded to the surfaces using a self-etch or total-etch bonding system. Shear force was applied, and the bond strengths of the specimens were measured. The data were analyzed using the Kruskal–Wallis test, followed by pairwise comparisons using Dunn’s test. The significance level for all tests was set at 0.05.

Results:
The sound (S) groups (33.81 ± 8.48) showed a significantly higher bond strength than the lesion (L) groups (25.77 ± 6.69). Among the pretreatments, CPP-ACFP-pretreated groups had the highest bond strength (33.86 ± 8.87). Pairwise comparisons showed significant differences between CPP-ACFP-treated demineralized enamel and control demineralized enamel in both bonding systems (P = 0.019 and P = 0.025 for Clearfil SE and Optibond FL, respectively).

Conclusion:
Pretreatment of demineralized enamel with CPP-ACFP before using total-etch and self-etch systems results in a bond strength comparable to that of sound enamel, making it clinically acceptable.
Tannic Acid Modulates Voltage-gated K+ Channels to Promote Neuritogenesis in Neuronal N2A Cells
Authors: Tsai Tien-Yao , Chuang Chin-Min , Wu King-Chuen , Yang Zih-He , Leung Yuk-Man 
Published: January 2025

Abstract
In a previous report, we showed that voltage-gated K+ (Kv) Kv1 and Kv2 channels are involved in cAMP-induced neuritogenesis of mouse neuronal N2A cells. In this report, we examined the effects of tannic acid (TA) on Kv channels and neuritogenesis in N2A cells. TA (15 μM) mildly enhanced Kv currents at −30 to −20 mV but strongly inhibited Kv currents at higher voltages, causing a preferential activation of currents at low voltages. When enhancement and suppression of Kv currents (at −20 and +70 mV, respectively) by different concentrations of TA were analyzed, TA at 4 μM produced strong enhancement at −20 mV with relatively mild suppression at + 70 mV. TA (4 μM) also promoted neuritogenesis; such promotion was suppressed by a Kv channel blocker tetraethylammonium ion, or a combination of hongotoxin-1 (blocker of Kv1.1), UK 78282 (blocker of Kv1.4) and guangxitoxin 1E (blocker of Kv2.1). Our results demonstrate, for the first time, TA at low concentrations could modulate Kv channels and thereby promote neuritogenesis.
Staff nurses’ perception of authentic leadership behavior of first-line managers and its relation to their resilience
Authors: Mohamed Shimaa Awad , Seada Abeer Mohammed , Ali Shaimaa 
Published: January 2025

Background
Authentic leadership is a suitable leadership model that results directly or indirectly in more positive workplace behaviors and attitudes, including staff nurses’ resilience. When staff nurses are susceptible to workplace stress, a manager has to create workplace that is optimal for the provision of nursing care by motivating, resilience, and empowering their nurses.

Aim
The study aimed to investigate staff nurses’ perception of authentic leadership behavior of first-line managers and its relation to their resilience.

Design
A descriptive correlational design was utilized to carry out the study.

Setting
This study was conducted in a new emergency hospital (185) at El-Kasr El-Aini Teaching Hospital, which is affiliated with Cairo University Hospital.

Patients
A convenient sample of 200 staff nurses constituted the study sample.

Tools
Three tools were used: (a) personal characteristics and work-related datasheet, (b) authentic leadership questionnaire, and (c) resilience scale.

Results
The study results revealed that the total mean percentage of staff nurses’ perception of authentic leadership behavior of first-line managers was 68%. Also, 63.5 and 31% of staff nurses had high to moderate levels of resilience, while 5.5% of them had low resilience levels. Moreover, there was a highly statistically significant positive correlation between all dimensions of staff nurses’ perception of authentic leadership behavior of first-line managers and all dimensions of staff nurses’ resilience (P˂0.05).

Conclusions
The study concluded that there is a positive correlation between staff nurses’ perception of authentic leadership behavior and their resilience as r=0.61 and P=0.0.

Recommendations
The study recommended that the staff nurses’ resilience levels be evaluated, and guidelines should be developed to ensure that staff nurses are encouraged to foster good work participation attitudes.
Perception of the health team regarding the expected role of informatics nurse in a selected automated unit at Cairo University Hospital
Authors: Abed Fatma A. , Etway Eman A.E. , Ali Marwa A.E. 
Published: January 2025

Background
In clinical practice, nursing informatics is crucial. In order to increase the quality of care, it is important to focus on the awareness needs of nurses in relation to nursing informatics roles.

Aim
To identify the perception of the health team regarding the expected role of the informatics nurse in a selected automated unit at Cairo University Hospital.

Design
A descriptive exploratory design was utilized in this study.

Patients
Convenient sample of nursing staff (n=70) and medical staff (n=30).

Setting
The study was carried out in two critical care units at New El-Kasr ElAiny Teaching Hospital, Cairo University.

Tool
One tool was used for data collection, consisting of three parts: the first part was personal characteristics data of nursing staff. The second part is personal characteristics data related to medical staff. The third part is related to the informatics nurse role questionnaire.

Results
There were statistically significant differences between nursing staff and medical staff regarding informatics privacy and informatics knowledge system.

Conclusion
The findings of the present study concluded that both nursing and medical staff highly perceived the role of informatics nurse.

Recommendations
Hospital administrators need to conduct training programs, workshops, and seminar to increase awareness and engagement of nurses about nursing informatics. Develop strategies to improve nurses’s informatics practice.
Orbital and adnexal sarcoidosis: Clinical presentations and management outcomes
Authors: Salim Shebin , Alam Md Shahid , Ahuja Sonam , Koka Kirthi , Pauly Marian , Krishnakumar Subramanian , Mukherjee Bipasha 
Published: January 2025

Purpose:
To present the clinical features and management outcomes in a series of patients with orbital and adnexal sarcoidosis.

Methods:
This was a retrospective analysis of 19 histopathologically proven cases of orbital and adnexal sarcoidosis over the past ten years. The data analyzed included demographic details, clinical and imaging features, and management outcomes. The response to treatment was categorized based on clinical improvement at the last follow-up as complete resolution, partial resolution, or no resolution.

Results:
There were 15 (78.9%) females and four (21%) males. The mean age at presentation was 51.05 ± 14.35 years. Upper lid swelling was the most common sign (n = 6), followed by lacrimal gland enlargement (n = 5). The specific locations of involvement were orbital soft tissues (n = 8), lid (n = 5), lacrimal gland alone (n = 3), lacrimal sac (n = 1), extra ocular muscles (n = 1), and conjunctiva (n = 1). An incisional biopsy was performed on 16 patients, and an excisional biopsy on three. Of those undergoing excisional biopsy, the lesion was located in the superonasal extraconal space in one and in the superotemporal lid in two. Twelve patients (63.2%) had systemic involvement at presentation. No further treatment was necessary for patients who underwent excisional biopsy. Additional treatments included oral steroids (n = 10) and systemic immunosuppressants (n = 5). Six patients were lost to follow-up. Complete resolution of signs and symptoms was noted in 11 patients (84.6%), while partial resolution was seen in two patients. The mean duration of follow-up was 7.56 ± 12.63 months.

Conclusion:
Sarcoidosis can affect any part of the orbit or adnexa, with varied presentations depending on the involvement. Excisional or incisional biopsies, along with systemic steroids and immunosuppressants in select cases, remain the mainstay of treatment.
Evaluating the combination of amoxicillin, gemifloxacin and rabeprazole therapy for Helicobacter pylori eradication in young and older adult patients
Authors: Kilic Guner , Kilic Gulce , Kayar Nuket  , Durmaz Ozan , Ozkahraman Adnan , Konur Sevki , Dertli Ramazan , Kayar Yusuf 
Published: January 2025

Purpose: To assess the effectiveness, safety and adverse effects of treatment regimen combining amoxicillin, gemifloxacin and rabeprazole for eradicating Helicobacter pylori in adult population.Methods: A total of 211 patients comprising 33 patients (15.6 %) from the older adult group and 178 patients (84.4 %) from the younger adult group who visited Van Training and Research Hospital, Turkey were included in this study. Treatment, made up of amoxicillin (1000 mg) and rabeprazole (20 mg), was administered 12 hourly and gemifloxacin (320 mg) once daily to all patients for 7 days. Thereafter, patients were evaluated for H. pylori eradication by examining antigens in feces (immunochromatographically based, qualitatively), drug compliance and treatment tolerance.Results: Post-treatment investigations showed that H. pylori was completely eradicated in 187 patients (88.6 %), while eradication was not achieved in 24 patients (11.4 %). In the older adult group, H. pylori was successfully eradicated in 27 of 33 patients (81.8 %). Excluding a total of 9 patients who did not complete treatment due to side effects, H. pylori eradication was achieved in 184 of 202 patients (91 %). Conclusion: This combination of three antibiotics exhibits a high rate of eradication of H. pylori among adult patients, even when administered for a short period (one week). This investigation should be carried out using a larger and more diverse patient population to validate the outcomes reported in this study.
Multidisciplinary telehealth interventions for autistic children in sub-Saharan Africa: challenges and recommendations
Authors: Agbamu Emmanuel , Balogun Kabeerat , Jasseh Mamat , Igwebuike Oluchukwu , Amoye Odunayo , Ahmed Aisha , Chernet Meskerm 
Published: January 2025

History of autism is plagued by misconceptions and distortions and it is mostly attributed to spiritual causes. A comprehensive literature search was conducted to identify studies of telehealth interventions in the management of autism in various countries, and related challenges in Sub-Saharan Africa. There were several obstacles in adopting multidisciplinary telehealth interventions (MTI) which include poor internet, epileptic power supply, cultural beliefs, and lack of political will. This commentary compiles historical misconceptions, MTI which could be scaled up to meet the health-care needs of autistic children in Sub-Saharan Africa and the challenges that follow. Furthermore, it presents some recommendations for integrating telemedicine into the healthcare system. This commentary advocates the need for incorporating telehealth in autism spectrum disorder (ASD) management to improve care accessibility in sub-Saharan Africa through a multidisciplinary telehealth approach involving health practitioners, caregivers, teachers, psychologists, behavioural therapists, policy-makers, information technology (IT) specialists, web and applications developers, and government officials. User- friendly, low-cost telehealth models such as Applied behavior analysis (ABA), Face your fears (FYF) model, Collaborative model for promoting competence and success (COMPASS), ImPACT program, Joint attention, symbolic play, engagement, and regulation (JASPER), and Early start Denver model (ESDM) improve health outcomes in various countries and may be reworked for implementation in Sub- Saharan Africa. Development of appropriate telehealth infrastructure, increasing education and training of healthcare professionals and patients, and the need for government support and funding would improve accessibility and practice of telehealth interventions.
Allicin-mediated renal protection in mitigating streptozotocin-induced diabetic nephropathy in rats through comprehensive restoration of kidney function and morphology
Authors: Dhanarasusa Sasikumar , Almuqati Afaf 
Published: January 2025

Purpose: To evaluate the benefits of allicin, a vital garlic component, against streptozotocin-induced diabetic kidney damage in rats.
Methods: A total of thirty male albino Wistar rats were divided into five groups of six rats each, with groups II – IV induced with diabetes using a single intraperitoneal administration of streptozotocin (55 mg/kg). Group I served as normal control while Group II was untreated diabetic control, receiving vehicle injections. Diabetic rats in Groups III and IV were treated with allicin (diallyl thiosulfinate, DATS, 20 mg/kg/day orally for 15 days) and aminoguanidine (AG, 100 mg/kg/day orally for 15 days), respectively, while Group V rats served as normal control rats receiving DATS only. Various biochemical, and kidney marker assessments and histological examinations were conducted at the end of treatment.
Results: Streptozotocin-induced diabetic rats exhibited significant (p < 0.05) alterations in body weight, kidney metrics, kidney markers and renal histopathology compared to normal control (Group I). Treatment with DATS showed significant improvements in body weight, kidney metrics and biochemical markers (p < 0.05) indicating potential nephroprotective effect against diabetic nephropathy by significantly restoring kidney weight, protein levels, albumin, potassium, sodium and other urinary markers (p < 0.05). Furthermore, DATS effectively reversed STZ-induced renal damage with outcomes comparable to standard drug (aminoguanidine).
Conclusion: Administration of DATS in rats with nephropathy from diabetes may have kidney protective benefits. The study highlights allicin’s potential as a therapeutic agent in managing diabetic complications, particularly diabetic nephropathy, prompting further exploration prior to future use.
Anti-hyperglycemic activities of Lepisanthes rubiginosa (Roxb.) Leenh. leaf and pericarp extracts in streptozotocininduced diabetic rats
Authors: Konsue Ampa , Butiman Chirapha , Luang-In Vijitra , Maneechai Suthira , Katisart Teeraporn 
Published: January 2025

Purpose: To evaluate the anti-hyperglycemic activities of Lepisanthes rubiginosa (Roxb.) Leenh. Leaf and pericarp extracts in streptozotocin-induced diabetic rats.Methods: Doses of 500 mg/kg of the leaf and pericarp extracts were administered orally once daily to both control and streptozotocin (65 mg/kg)-induced diabetic rats for 28 days. Changes in body weight, blood glucose, triglycerides, liver and kidney function tests as well as histopathological examination of the liver cells post-administration of the extracts were evaluated and compared.Results: Administration of 500 mg/kg of these two extracts to diabetic rats resulted in a significant increase (p < 0.05) in body weight, a significant reduction (p < 0.05) in fasting blood glucose, and a decrease in triglycerides after 4 weeks of treatment compared to diabetic controls, without affecting other hematological values. Liver function tests showed a decrease (p < 0.05) in aspartate aminotransferase levels, while kidney function tests indicated a significant reduction (p < 0.05) in blood urea nitrogen levels.Conclusion: Lepisanthes rubiginosa (Roxb.) Leenh. Leaf and pericarp extract effectively lower blood glucose levels in diabetic rats by restoring pancreatic histopathology, resulting in an increase in the size of islets of Langerhans and promoting the cells thereby leading to increased insulin secretion.