bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Comprehensive review of Nigella sativa (kalonji) from the Unani perspective
Authors: Alam Mahboob , Bhat Shabir Ahmad , Rather Shameem Ahmad , Hakeem Naseer Ahmad , Khalique Abdul , Mobin Sana , Azmi Fauzia , Mariyam Zamal 
Published: October 2023

The remarkable therapeutic properties of Nigella sativa, often known as black seed or kalonji are well recognized. The use of N. sativa seeds and its oil has a long history in various traditional food and medical systems. As stated by the holy prophet of Islam (PBUH), Shoneez is important since it can cure all diseases with the exception of death. It is widely used in several conventional medical systems, including Unani Tibb, Chinese medicine, Ayurveda, and Siddha.
The goal of the current review is to provide a thorough overview of the literature on scientific studies of the pharmacognostical properties, chemical makeup, and pharmacological activity of the seeds of this plant.
The data was collected from various reputed data bases like PubMed, Science direct, Web of Saciences, Google Scholar and Research Gate. The traditional and Unani literature was also searched from the classical books of Greco-Arab medicine in addition to other digital sources.
According to traditional Unani literature, N. sativa exhibits a variety of pharmacological properties, including those that are carminative, anti-inflammatory, analgesic, diuretic, emmenagogue, galactagogue, and expectorant. Numerous phytochemical, pharmaceutical, and clinical studies have been conducted on N. sativa, revealing its potential anti-diabetic, anti-cancer, immunomodulator, analgesic, antimicrobial, anti-inflammatory, bronchodilator, renal protective, gastro-protective, antioxidant, and other properties. N. sativa is among the top-ranked evidence-based herbal medications because of its remarkable healing ability. The main bioactive component of the essential oil, thymoquinone, is responsible for the majority of its medicinal capabilities.
Nigella sativa is a potent herb which exhibits wide range of pharmaceutical properties, most of which have been confirmed via preclinical and clinical studies. This review may thus be useful for the research community in particular and common people in general to avail the benefits of N. sativa.
Keywords: Anti-cancer, Kalonji, Habat-ul-Sauda, Shoneez, Thymoquinone, Nigella sativa, Unani
The Utilization of Secang Wood (Caesalpinia sappan L.) Extract Nanoemulsion as Natural Pigment in Lip Cream Preparations
Authors: Agustin Eriska , Pratiwi Aknes 
Published: October 2023

Lip cream is a semi-solid lipstick preparation. One of the important ingredients in lipcream preparations is a variety of colorants. Secang wood contains the active compound brazilin which gives it a yellow to purple color which can be used as a natural dye. The conventional lip cream preparations from extracts have low homogeneity and unstable, so it is necessary to increase the stability of the preparation by making a nanoemulsion of secang wood extract which is incorporated into the lip cream preparation. The preparation of 10% secang wood extract nanoemulsion preparation using Tween 80, Virgin Coconut Oil (VCO), and PEG 400 with particle size reduction using a bath sonicator. The concentration of the nanoemulsion preparation was 1% (F3) and 3% (F4) incorporated into the lip cream base and conventional lip cream preparations with the same concentration (F1 and F2). The test results for the size of the 10% secang wood extract nanoemulsion globules were 127.54 ± 0.45 nm (PI: 0.3 ± 0.013). The test results for the F3 and F4 nanoemulsion lipcream preparations had a pink to purple color, pH 6-6.4, spreadability of 5.9-6.8 cm, adhesion of 5.5-6 seconds, the preparation was homogeneous and non-irritating, compared with conventional lip cream preparations F1 and F2 are not homogeneous, the color of the lip cream is paler, and the irritating properties are very mild in both formulas. The conclusion of this research is that secang wood extract can be formulated into a nanoemulsion preparation and incorporated into a lip cream preparation.
Keywords: Brazilin, Color, Dye, Sonicator Bath
Overview of Analytical Methods for the Determination of H2 Receptor Blockers: A Review
Authors: Adhikari Rudra Prasad , Rahman Samima Nasrin , Lamichhane Suman , Bora Aditya 
Published: October 2023

Overview of various analytical methods for estimating anti-histaminic (H2 Receptor blockers) drugs, particularly for determining their concentration percentage (assay) by analytical methods developed on analytical instruments i.e., UV visible Spectrophotometer, High-Performance Liquid Chromatography, and Hyphenated techniques. The review includes a literature survey of H2 receptor blocker drugs namely cimetidine (Tagamet), ranitidine (Zantac), famotidine (Pepcid, Pepcid AC), and nizatidine (Axid). The examined literature survey addressed chromatographic (HPLC) and UV visible spectrophotometric methods with LC-MS/MS methods used in pure forms, pharmaceutical formulations, human plasma, and other biological fluids for their estimation. In the case of validation parameters, mostly Linearity, Recovery study, LOD, and LOQ were considered and mentioned. This review helps researchers to get detailed information regarding various analytical methods of development and validation for H2 receptor antagonists.
Keywords: H2 Receptor blockers, HPLC, Analytical methods, ranitidine, famotidine, nizatidine.
Formulation and Evaluation of Buccal Patches of Diclofenac Sodium as a Model Drug
Authors: Das Debjani , Sur Pallabi , Das Sudipta 
Published: October 2023

The present study was concerned with the formulation and evaluation of buccal patches of Diclofenac Sodium. Here, Diclofenac sodium is used as a model drug. Buccal patches of Diclofenac Sodium were preparedby solvent casting method using PEG 400, Glutaraldehyde, Glycerin, HPMC, Gelatin and required quantity of distilled water. Weight variation, thickness, drug content and release studies were assessed.
Keywords: Buccal patch, Diclofenac sodium, oral mucosa, HPMC, PEG-400, Glutaraldehyde.
Investigation of the Protective Effect of Terebinth (Pistacia terebinthus L.) against Ovarian Ischemia-Reperfusion Damage in Rat
Authors: Şengül Gülsüm Pektanç , Deveci Engin , Şengül Seydi Ahmet , Tekelioğlu Yavuz 
Published: October 2023

The aim of this study is to investigate the therapeutic and protective effects of Pistacia terebinthus L. (terebinth) oil treatment on experimental ovarian ischemia and reperfusion injury in rats. In the study, 32 Sprague-Dawley female rats; They were divided into 4 groups: control, ischemia, ischemia/reperfusion (I/R), ischemia/reperfusion + terebinth oil (I/R + terebinth oil), 8 in each group. Terebinth oil was applied via oral gavage at a daily dose of 2 ml/kg for 4 weeks. In histopathological examination of ovarian sections, the control group showed a regular histological appearance. In the ischemia and I/R groups, degenerations in the epithelium, inflammatory cell infiltration in the lamina propria region, and bleeding due to thrombosis in the enlarged vessels were observed. It was determined that terebinth oil protected the epithelial tissue after ovarian I/R injury, reduced inflammation in the connective tissue, and brought the artery-vein contours to a regular appearance. In the ovarian sections where immunohistochemistry analysis was performed, it was observed that radixin protein expression showed a positive reaction in the granulosa cells and a negative reaction in the stromal areas in the terebinth oil applied group compared to the I/R group. As a result, it was revealed that terebinth oil has a healing and protective effect in the treatment of ovarian ischemia/reperfusion injury.
Keywords: Terebinth (Pistacia terebinthus L), Ovary, Ischemia, Reperfusion
SEXUAL HARASSMENT BY CHILDREN IN THE ACEH PROVINCE: A CASE STUDY ON THE JINAYAT BYLAW
Authors: Nur Muhammad , Harun Harun , Bakry Nurdin 
Published: October 2023

The Aceh province is a special autonomous region with the authority to carry out Islamic Sharia. Article 125 of Law Number 11 of 2006 concerning the Aceh Government emphasizes that the Sharia implemented in Aceh includes aqidah (creed), syar'iyah, and akhlaq (disposition). However, Sharia implementation in Aceh has not fully affected the social conditions of its people, especially since child crimes, such as sexual harassment, still happen. Acehnese people are religious and view the relationship between men and women as sacred and can only happen through marriage. Hence, sexual harassment is against the Acehnese people's Islamic life views and beliefs. This study aims to explain the factors that cause children to commit sexual harassment in Aceh Province. This study is empirical legal research that collects primary and secondary data. Data analysis employed a descriptive-analytical approach. The study shows that children commit sexual harassment in Aceh due to two factors, namely internal factors, i.e., children's lack of religious knowledge and sexual desire, and external factors, i.e., lack of parental supervision as well as influence from communication and social media.
Abstrak: Propinsi Aceh sebagai Daerah Otonomi khusus mempunyai kewenangan untuk menjalankan syari’at Islam, dalam Undang-Undang Nomor 11 Tahun 2006 tentang pemerintah Aceh, pada Pasal 125 ditegaskan bahwa Syari’at Islam yang dilaksanakan di Aceh meliputi aqidah, syar’iyah dan akhlak. Namun kebijakan penerapan syari’at Islam di Provinsi Aceh belum sepenuhnya berpengaruh terhadap kondisi social masyarakatnya, terutama masih terjadi tindak criminal yang dilakukan oleh anak yaitu Pelecehan seksual. Pada dasarnya masyarakat Aceh adalah masyarakat yang religius, dan memandang hubungan antara laki-laki dan perempuan sebagai hubungan yang sakral. Hubungan tersebut hanya dapat dilakukan melalui lembaga perkawinan. Sehingga tindak pidana pelecehan seksual sangat bertentangan dengan pandangan hidup dan keyakinan masyarakat Aceh yang Islami. Penelitian ini bertujuan untuk menjelaskan bagaimanakah faktor penyebab anak melakukan pelecehan seksual di Propinsi Aceh. Penelitian ini menggunakan penelitian hukum empiris, pengumpulan data dilakukan melalui data primer dan data sekunder. Analisis data menggunakan pendekatan deskriptif-analitik. Berdasarkan hasil penelitian dapat diketahui bahwa anak melakukan pelecehan seksual di Propinsi Aceh disebabkan oleh dua factor yaitu factor internal, berupa; anak kekurangan ilmu pengetahuan agama dan dorongan nafsu birahi. Adapun faktor eksternal, anak melakukan pelecehan seksual karena kurang mendapatkan pengawasan orang tua dan pengaruh media komunikasi dan media social.
Kata Kunci: Pelecehan Seksual, Anak Sebagai Pelaku, Hukum Jinayat
LEGISLATIVE ELECTIONS: AN OVERVIEW OF CLOSED PROPORTIONAL SYSTEM
Authors: Mutawalli Muhammad , Maskun  , Ayub Zainal Amin , Tajuddin Muhammad Saleh , Wahab Harlida Abdul 
Published: October 2023

This study aims to analyze the constitutionality of legislative general elections with a review of the closed proportional system in the 1945 Constitution. The legislative election system is an important tool for maintaining democratic principles and fair representation in a country. The constitutionality of the closed proportional system has been the subject of ongoing debate. This study uses a qualitative approach with normative juridical methods to analyze the constitutionality of general legislative elections that use a closed proportional system. This approach involved collecting data from legal documents, literature studies, and court decisions that were relevant to this topic. The results of the study showed that the application of a closed proportional system in legislative general elections has several constitutional implications, such as the limitation of political access for individuals outside of political parties, which can be considered as a violation of the individual's constitutional right to participate in the political process. This research also showed that a closed proportional system can provide greater political stability and strengthen the role of political parties in the political system. This study also analyzed the implications of implementing an open proportional system in legislative general elections.
Abstrak: Penelitian ini bertujuan untuk mengkaji konstitusionalitas pemilihan umum legislatif dengan tinjauan terhadap sistem proporsional tertutup dalam UUD 1945. Sistem pemilihan umum legislatif adalah aspek penting dalam menjaga prinsip demokrasi dan keterwakilan yang adil dalam sebuah negara. Sistem proporsional tertutup telah menjadi subjek perdebatan yang berkelanjutan mengenai konstitusionalitasnya dalam konteks UUD 1945. Penelitian ini menggunakan pendekatan kualitatif dengan metode yuridis normatif untuk menganalisis konstitusionalitas pemilihan umum legislatif dengan menggunakan sistem proporsional tertutup. Pendekatan ini melibatkan pengumpulan data dari dokumen hukum, studi literatur, dan putusan pengadilan yang relevan dengan topik ini. Hasil penelitian menunjukkan bahwa penerapan sistem proporsional tertutup dalam pemilihan umum legislatif memiliki beberapa implikasi konstitusional. Pertama, sistem ini dapat membatasi akses politik bagi individu di luar partai politik, yang dapat dianggap sebagai pelanggaran terhadap hak konstitusional individu untuk berpartisipasi dalam proses politik. Penelitian ini juga menganalisis implikasi penerapan sistem proporsional terbuka dalam pemilihan umum legislatif. Penelitian ini juga menunjukkan bahwa sistem proporsional tertutup dapat memberikan stabilitas politik yang lebih besar dan memperkuat peran partai politik dalam sistem politik.
Kata Kunci: Konstitusionalitas, Pemilihan Umum Legislatif, Sistem Proporsional Tertutup, UUD 1945, Kebebasan Politik
ROBOTICS AND AUTOMATION: THEIR IMPACT ON THE SOCIAL SECURITY OF CRITICAL INFRASTRUCTURE WORKERS
Authors: Kaylo Ivan , Lubinets Dmytro , Kryvenko Dmytro , Mykolaiets Dmytro , Platonova Hanna 
Published: October 2023

Automated robotics is significantly changing the way we live and work. The use of automation technologies is becoming more and more common either in manufacturing or in healthcare. This technology improves workplace safety significantly since robots can perform dangerous or repetitive tasks. It also reduces the risk of injury to workers. The topic of robotics and automation is relevant in Ukraine, given the war and the frequent shelling of critical infrastructure facilities. Currently, robotics and automation have great potential to improve the social security of critical infrastructure workers in conditions of war and frequent shelling of objects. They can ensure safety, productivity, and operational stability and improve emergency response capabilities. The purpose of the article is to study the issue of robotics and automation in the modern world and their impact on the social security of critical infrastructure workers in particular.
Abstrak: Robotika otomatis secara signifikan mengubah cara kita hidup dan bekerja. Penggunaan teknologi otomasi menjadi semakin umum baik di bidang manufaktur maupun di bidang kesehatan. Teknologi ini meningkatkan keamanan tempat kerja secara signifikan karena robot dapat melakukan tugas berbahaya atau berulang. Ini juga mengurangi risiko cedera pada pekerja. Topik robotika dan otomasi relevan di Ukraina, mengingat perang dan seringnya penembakan fasilitas infrastruktur penting. Saat ini, robotika dan otomasi memiliki potensi besar untuk meningkatkan jaminan sosial pekerja infrastruktur kritis dalam kondisi perang dan seringnya penembakan objek. Mereka dapat memastikan keselamatan, produktivitas, dan stabilitas operasional serta meningkatkan kemampuan tanggap darurat. Tujuan artikel ini adalah untuk mempelajari masalah robotika dan otomasi di dunia modern dan dampaknya terhadap jaminan sosial pekerja infrastruktur kritis pada khususnya.
Kata Kunci: Otomatisasi, Infrastruktur Kritis, Robotika, Jaminan Sosial Pekerja, Perlindungan Pekerja
PSEUDO-ENVIRONMENTAL VALUES VERSUS ETHICAL SPIRITUALITY: A STUDY ON INDONESIAN GREEN SUKUK
Authors: Bin-Armia Muhammad Syauqi 
Published: October 2023

This paper investigates and inspects the application of green sukuk as an Islamic environmentally accepted bond and its impacts on the global market. Law No.19 of 2008 on Shariah Government Securities, governs the exercise of green sukuk that accepts two basic norms, Shariah compliance and ecosystem friendly. Philosophically speaking, environmental preservations are embedded in Shariah as a core principle. Shariah persuaded unharmed human beings as well as other creatures. The amalgamation between the sharia principle and environmental values out to be sufficient to manifest the objective. The research aims to examine the worthiness of new emerging sukuk while carrying the same basic principle on moral, ethical and environmental embeddedness within the sukuk itself. The research methodology conducted in this research will implement mixed-methods through qualitative and quantitative approaches. The research indicates that green sukuk issuance has no contribution toward global sukuk performances signaled by selected sukuk indices on the issuance date. In addition, there are no sufficient assessment mechanism indicators to ensure the application of environmental distinctive values and shariah compliance implimentations.
Abstrak: Tulisan ini menyelidiki penerapan green sukuk sebagai obligasi Islam yang ramah lingkungan dan dampaknya terhadap pasar global. Undang-Undang Nomor 19 Tahun 2008 tentang Surat Berharga Syariah Negara (SBSN) mengatur pelaksanaan green sukuk yang menganut dua norma dasar, yaitu kepatuhan syariah dan ramah ekosistem. Secara filosofis, pelestarian lingkungan hidup tertanam dalam syariah sebagai prinsip inti. Syariah mengatur prinsip untuk tidak merugikan manusia dan juga makhluk lainnya. Penggabungan antara prinsip syariah dan nilai-nilai lingkungan sudah cukup untuk mewujudkan tujuan tersebut. Penelitian ini bertujuan untuk menguji kelayakan jenis sukuk yang baru ini dengan tetap mengusung prinsip dasar yang sama mengenai keterikatan moral, etika, dan lingkungan dalam sukuk itu sendiri. Metodologi penelitian yang dilakukan dalam penelitian ini akan menerapkan mix-methods melalui pendekatan kualitatif dan kuantitatif. Hasil penelitian menunjukkan penerbitan green sukuk tidak memberikan kontribusi terhadap kinerja sukuk global yang ditunjukkan oleh indeks sukuk pada tanggal penerbitan. Selain itu, tidak ada indikator mekanisme penilaian yang memadai untuk memastikan penerapan nilai-nilai keistimewaan lingkungan dan kesuksekan dampak syariah pada sukuk tersebut.
Kata kunci: Sukuk Hijau, Lingkungan, Benturan Nilai, Pasar Modal.
PENGEMBANGAN BAHAN AJAR TEMATIK BERBASIS WEB MENGGUNAKAN WEEBLY PADA TEMA 8 SUBTEMA 1 KELAS IV SEKOLAH DASAR
Authors: Hasanah Zidni Ulfi , Simanungkalit Erlinda , Sembiring Masta Marselina , Handayani Dilla 
Published: October 2023

Tujuan dari penelitian ini adalah untuk mengetahui apakah penggunaan bahan ajar web berbasis Weebly pada tema 8 subtema 1 kelas IV SD Negeri 065000 Medan Marelan layak dan efektif. Hasil penelitian dan pengembangan ini, yang mengacu pada model penelitian dan pengembangan ADDIE, menunjukkan bahwa bahan ajar berbasis web yang dikembangkan menggunakan Weebly memperoleh presentase kelayakan dari ahli media sebesar 75% dan dinyatakan "layak", presentase kelayakan dari ahli materi sebesar 85,71% dan dinyatakan "sangat layak", dan presentase kelayakan dari praktisi pendidikan sebesar 97,3% dan dinyatakan "sangat layak". Hasil dari tahap uji coba lapangan menunjukkan bahwa bahan ajar berbasis web weebly memenuhi kriteria keefektifan dengan nilai sekitar 85,71% pada post-test dari 21 peserta didik. Dengan demikian, bahan ajar berbasis web ini dianggap layak digunakan dalam proses belajar dan mengajar.
PENGARUH MODEL PEMBELAJARAN KOOPERATIF TIPE MURDER TERHADAP HASIL BELAJAR SISWA KELAS V SD NEGERI 1 TEGALYOSO KLATEN TAHUN PELAJARAN 2022/2023
Authors: Hidayah Elviyani Nur , Susatya Jajang , Rofsina Nela 
Published: October 2023

Tujuan penelitian ini adalah untuk mengetahui pengaruh yang signifikan pada penerapan model pembelajaran kooperatif tipe MURDER terhadap hasil belajar siswa kelas V SD Negeri 1 Tegalyoso Klaten Tahun Pelajaran 2022/2023. Jenis penelitian ini adalah Quasi Eksperimen dengan desain penelitian control group pretest-posttest design. Populasi penelitian berjumlah 38 siswa. Teknik pengambilan sampel yang digunakan adalah sampel jenuh. Pengumpulan data menggunakan tes. Teknik analisis data dilakukan uji normalitas, uji homogenitas, dan uji hipotesis. Dari hasil perhitungan uji-t didapat thitung sebesar 5,254 dengan tabel df = 36 adalah 2,028 artinya thitung 5,254 > ttabel 2,028, maka dapat ditarik kesimpulan bahwa H0 ditolak dan Ha diterima. Dengan hasil uji N-Gain Score dalam persen untuk kelas eksperimen adalah sebesar 69,7% termasuk dalam kategori tafsiran Cukup efektif. Penelitian ini menyimpulkan bahwa terdapat pengaruh yang signifikan pada penerapan pembelajaran dengan model pembelajaran kooperatif tipe MURDER terhadap hasil belajar siswa kelas V, yaitu hasil belajar siswa mengalami peningkatan, keterlibatan yang aktif dan penuh semangat dalam proses belajar, serta terjalinnya kerjasama yang baik antara siswa dalam kegiatan kelompok dan diskusi.
DESAIN OUTCOME BASED EDUCATION MELALUI PENGEMBANGAN BUKU BERBASIS SMART PADA MATA KULIAH ATLETIK
Authors: Sihombing Hardodi , Usman Khairul , Naufal Achdan Ahmad , Al Aini Sela , Riandra Muhammad Naoval 
Published: October 2023

Tujuan pada penelitian ini adalah untuk menghasilkan buku berbasis smart pada mata kuliah atletik berdasarkan desain outcome based education. Desain outcome based education (OBE) melalui pengembangan buku berbasis smart pada mata kuliah atletik menggunakan desain penelitian research and development (RnD). Kegiatan penelitian yang dimaksud adalah mengembangkan produk pembelajaran berupa sebagai pendukung terlaksananya OBE secara maksimal. Pengembangan produk dilakukan dengan upaya validasi untuk memberikan pembuktian terhadap produk yang akan digeneralisasi. Prosedur pengembangan buku berbasis smart pada mata kuliah atletik sebagai optimalisasi pelaksanaan OBE dilakukan dengan pendekatan ADDIE, yang merupakan perpanjangan dari analysis, design, development, implementation, dan evaluation. Hasil akhir pada media menunjukkan penilaian 91 yang memiliki terjemahan bahwa buku berbasis smart sudah memiliki kesesuaian dan sangat baik untuk penerapannya pada perkuliahan atletik berbasis OBE. hasil penilaian ahli materi menunjukkan bahwa pada tahap 1 penilaian isi materi buku berbasis smart memiliki penilaian 43 yang memiliki makna kategori sangat tidak baik. Hasil evaluasi atau penilaian produk memperoleh keterangan bahwa konsep desain OBE melalui pengembangan buku berbasis smart pada mata kuliah atletik menggambarkan konsep tampilan buku yang mendukung proses pelaksanaan sesuai dengan CPL dan CPMK perkuliahan dan dapat dilaksanakan pada konsep case method dan team based project.