bluuebunny/crossref_metadata_2025_split huggingface dataset:
Do patients experience decisional regret after sacral neuromodulation for refractory overactive bladder?
Authors: Kessler Leia , Illinsky Daniel , Laudano Melissa , Abraham Nitya E. 
Published: October 2023

AbstractObjectiveSuccess following urological procedures is traditionally defined through objective endpoints. This approach may not capture the impact on patient satisfaction. There is a paucity of literature evaluating patient‐centered metrics such as satisfaction and decisional regret in the field of urology. This study investigates long‐term satisfaction and decisional regret amongst patients who underwent sacral neuromodulation (SNM) for the treatment of refractory overactive bladder (OAB).Materials and MethodsThis study retrospectively reviewed patients who underwent SNM for refractory OAB from 2015 to 2022 at a single institution serving an ethnically diverse and underrepresented community. Demographic data were collected through chart review and surveys conducted via telephone calls. Patient satisfaction and decisional regret was measured with the validated modified SDS‐DRS scale (satisfaction with decision scale‐decision regret scale). Descriptive statistics, Wilcoxan rank sum, and median regression analyses were performed using STATA 15.0 with p < 0.05 as significant.ResultsOut of 191 patients who underwent SNM, 63 were unreachable (wrong number in chart, number not in service, patient did not answer, deceased). Eighty‐nine out of 128 patients reached agreed to participate (70% response rate). The mean time since surgery was 37.3 ±25.2 months. The median satisfaction with decision score was 4.0 (IQR: 3.7−4.7) with a score of 1 correlating with low satisfaction and a score of 5 correlating with high satisfaction. The median decisional regret score was 2.0 (IQR: 1.2−2.9) with a score of 1 correlating with low decisional regret and a score of 5 correlating with strong decisional regret. Ten patients reported complications after surgery, which was significantly associated with lower SDS and higher DRS scores (p < 0.01), and persisted after adjusting for age, body mass index, sex, and comorbidities (SDS β coef: −0.84, 95% CI: −1.5 to 0.15, p = 0.02; DRS β coef: 1.48, 95% CI: 0.55−2.41, p < 0.01).ConclusionsPatients who underwent SNM for refractory OAB overall had low regret and high satisfaction with their decision at an average 3 years of follow‐up. As expected, those who developed postoperative complications had worse scores. The inclusion of patient‐centric outcomes is imperative when determining the success of a surgical procedure and is useful for shared decision‐making when advancing to third‐line therapy for OAB. Longer‐term follow‐up is necessary to assess durability of high satisfaction and low regret over time.
The impact of COVID‐19 on Australian clinicians' decision making in line with the principles of Choosing Wisely
Authors: Giles Megan , Terblanche Morne , Wang Liang , Hirani Shashivadan P. , Wu Chiung‐Jung (Jo) 
Published: October 2023

AbstractAimTo explore the perspectives of clinicians' decision‐making processes and considerations in line with the Choosing Wisely principles during the first wave of the COVID‐19 pandemic.DesignAn exploratory qualitative approach was used.MethodsData were collected via semi‐structured interviews to encourage participants to discuss their own experience in making clinical decisions during the COVID‐19 pandemic. A total of 12 clinicians from across disciplines were interviewed to reach data saturation. Interview data were analysed considering the Choosing Wisely principles.ResultsFive main themes as they relate to clinician decision‐making emerged and included; prioritizing care and treatment, uncertainty regarding best practice as a result of rapidly changing guidelines, organizational challenges to clinical decision‐making, the use of telehealth and enabling consumer engagement with health services.ConclusionDespite the disruption caused by COVID‐19, clinicians were mindful of necessary care and worked to ensure that core care was not compromised during the first wave of the pandemic. The need for clinicians to protect both their own safety and that of their colleagues arose as an additional factor that influenced clinicians' decision‐making process during the COVID‐19 pandemic.
Quality of interaction between the nursing personnel and the informal caregivers of people with memory disorders: A systematic review and metasummary of qualitative studies
Authors: Rannikko Johanna , Paananen Jenny , Stolt Minna , Suhonen Riitta 
Published: October 2023

AbstractAimTo explore the factors that affect the quality of interactions between nursing personnel and the informal caregivers of people with memory disorders.DesignSystematic review and metasummary of qualitative empirical research.MethodsThe literature search targeted studies concerning the professional care interactions between nursing personnel and the informal caregivers of people with progressive memory disorders. The search in PubMed, CINAHL, PsycINFO and Scopus covered records from the earliest possible date up to December 2020. The data were summarised using a qualitative metasummary method. Preferred Reporting Items for Systematic reviews and Meta‐Analyses (PRISMA) checklist was used to validate the reporting process.ResultsTen articles were included. As presented in 33 statements, the factors affecting the quality of interactions were related to (1) expectations, (2) memory disorders, (3) interaction strategies, (4) time and place of interactions and (5) organisational aspects. Meeting the individual interactional needs of informal caregivers is recommended. The results provide guidance for improving the quality of interactions between nursing personnel and informal caregivers.
Peridynamic framework to model additive manufacturing processes
Authors: Hesse Jan‐Timo , Willberg Christian , Hein Robert , Winkelmann Felix 
Published: October 2023

AbstractThis paper introduces a novel framework for analyzing additive manufacturing processes. By employing a peridynamic mesh‐free implementation, it overcomes certain limitations encountered with finite element‐based approaches in regard to defects and fractures. The framework includes the implementation of thermodynamical material behavior and a novel boundary detection algorithm, as the outer surface area will undergo changes during the manufacturing process. The proposed methods are thoroughly validated, and a comprehensive example is provided as a demonstration.
Biodegradable nanocomposites prepared from poly(butylene adipate terephthalate) and silver nanoparticles for applications as disposable medical equipments
Authors: Zhao Xinshuang , Kang Le , Zhang Baogang , Liu Li , Sun Haozhi , Shen Xin , Su Feng , Li Suming 
Published: October 2023

AbstractSilver nanoparticles (AgNPs) were prepared using polyvinylpyrrolidone (PVP) as reducing and stabilizing agent. AgNPs were then embedded in a biodegradable poly(butylene adipate terephthalate) (PBAT) matrix by solution casting. The resulted PBAT/AgNPs nanocomposite films were characterized using various analytical techniques such as scanning electron microscopy (SEM), colorimeter, Ultraviolet–visible (UV–vis) spectroscopy, Fourier transform infrared (FT‐IR) spectroscopy, X‐ray diffraction (XRD), thermogravimetric analysis (TGA), mechanical tests and water vapor permeability measurements. The composite films appeared smooth on surface with some agglomeration of AgNPs. The addition of AgNPs led to color changes, and strongly improved the thermal stability, UV barrier performance, mechanical properties and water vapor barrier performance of composite films. Importantly, PBAT/AgNPs films present outstanding antibacterial activity against gram‐positive bacteria (Escherichia coli) and gram‐negative bacteria (Staphylococcus aureus). Moreover, composite films exhibit good stability under accelerated aging conditions and during high‐pressure sterilization. Therefore, biodegradable PBAT/AgNPs nanocomposite materials could present great potential for applications as disposable medical equipments.
Vibrational behavior of a 3D printed biomimetic dual‐core composite sandwich beam: An experimental and numerical study
Authors: Thanikasalam Narayanan , Ramamoorthy Manoharan 
Published: October 2023

AbstractComposite sandwich structures have been used in various applications like aerospace, automotive, and maritime sectors. The process of identifying the core design and the selection of a prominent core is crucially important in sandwich structures. In this study, biomimetic core development and vibration responses of composite sandwich beams with a dual biomimetic honeycomb core are investigated. The composite face layers are fabricated by the hand lay‐up method, and the fused deposition modeling is used to 3D print the PLA honeycomb cores. Based on ASTM‐E1876 and the alternative dynamic approach, the face layer elastic properties and rigidity modulus of the cores are evaluated, respectively. The numerical simulation is used to predict the sandwich panels' natural frequencies and mode shapes and verified with experimental results. There was an excellent agreement between the calculated and experimental natural frequencies. Due to the presence of the core and enhanced rigidity modulus, the dual lamellar honeycomb core sandwich beam produces the highest natural frequencies among all‐composite sandwich beams, followed by the dual regular honeycomb, single lamellar honeycomb, and single regular honeycomb cores. The geometric parametric studies, including core thickness, length‐to‐breadth ratio, lamination schemes, support conditions, and transverse vibration responses were also analyzed for different sandwich patterns. As a result of this work, thick composite sandwich panels in aeronautical and marine structures can be replaced with dual biomimetic core structures. The study highlights the fact that the dual‐core sandwich beam provided greater modal frequency than the single‐core beam with the same weight proportions.Highlights
Pistachio nut shell‐based biomimetic honeycomb core has been developed.
Alternative dynamic approach is used to find sandwich‐core shear properties.
Lamellar‐infused biomimetic model yields higher shear modulus and stiffness.
Dual‐core beam having high flexural stiffness enhances the natural frequency.
Various parametric studies were analyzed for different sandwich patterns.
Pain interference, pain type, and quality of life among adults with spina bifida
Authors: Smith Alexis V. , Richardson Elizabeth J. , Cowan Rachel 
Published: October 2023

AbstractIntroductionIndividuals with spina bifida (SB) experience nociceptive and neuropathic pain, and women with SB report more pain. However, the relationship between pain type and gender on pain interference and quality of life (QoL) among individuals with SB is less understood.ObjectiveTo assess relationships among pain interference, pain quality, participation‐related QoL, and gender among adults with SB.DesignFifty‐one adults with SB completed a self‐report survey assessing SB characteristics, pain severity, pain type, pain interference, and QoL.SettingHospital outpatient adult SB clinic.InterventionsNot applicable.Main Outcome MeasuresMeasures of nociceptive pain quality, neuropathic pain quality, participation‐related QoL, as well as pain interference with general activities, mood, and sleep were selected a priori as study measures.ResultsFifty‐eight percent (N = 30) reported pain and more women than men reported pain (69% vs. 38%, p = .003). Higher general pain interference was associated with lower QoL (r = 0.444, p = .042), but not mood or sleep pain interference (both p's ≥ .451). There was no statistically significant difference in pain interference between genders (p = .138). Nociceptive pain was more common. Levels of nociceptive pain were positively associated with general pain interference, sleep pain interference, and mood pain inference. Neither pain type was associated with QoL (both p's > .082).ConclusionsThe results from this study reveal key differences/similarities among four interrelated factors: pain, pain interference, QoL, and gender. Pertinent information gathered on pain type and QoL, like increased prevalence of nociceptive pain, can be utilized to formulate proactive and effective treatment plans for individuals with SB that may benefit their sleep pain interference and mood pain interference.
Hydrophilic cryogels as potential 3D cell culture materials: Synthesis and characterization of 2‐(methacrylamido) glucopyranose‐based polymer scaffolds
Authors: Behrendt Florian , Pretzel David , Cseresnyés Zoltán , Kleinsteuber Maximilian , Wloka Thomas , Radosa Lukáš , Figge Marc Thilo , Gottschaldt Michael , Brakhage Axel , Schubert Ulrich S. 
Published: October 2023

AbstractCell cultures are important techniques to investigate cellular processes in a simplified manner. The most commonly applied 2D models do not simulate most of the in vivo conditions whereas cryogels as promising 3D cell culture materials are able to provide both a structured microenvironment and tailored surface properties, similar to the natural extracellular matrix (ECM). Herein, we present the synthesis and characterization of hydrophilic cryogels with different 2‐(methacrylamido) glucopyranose amounts followed by 3D cell culture experiments with L929 cells. Selected samples are additionally functionalized with fibronectin‐FITC for improved cellular adhesion. The incorporation of different 2‐(methacrylamido) glucopyranose amounts into the cryogels is demonstrated by Fourier‐transform IR (FTIR) and solid‐state NMR (ssNMR). The gels are able to withstand harsh autoclaving conditions as shown by thermogravimetric analysis (TGA) and ssNMR measurements. Pore size measurements by automated scanning electron microscopy (SEM) image analysis reveal similar pore sizes among the entire cryogel series. Confocal laser scanning microscopy (CLSM) images suggest the presence of healthy cells due to the absence of morphological abnormalities among the entire cryogel series. L929 cells settled deeper into the cryogels with increasing MAG content. With additional fibronectin functionalization, the cells are retained much stronger and stay in the upper gel layers.
Alkoxy substitution on simple non‐fused electron acceptors for tuning the photoelectric properties of organic solar cells
Authors: Wang Lei , Cao Mingwei , Wang Miao , Gao Huanhuan , Shi Qiong 
Published: October 2023

AbstractIn order to identify high‐performance non‐fused ring electron acceptors for bulk heterojunction (BHJ) solar cells, six structurally diverse molecules are designed and categorized into two series. The first series is anchored by R1 as the reference molecule, featured fixed BDT, IC‐2F end groups and modified π bridges. The second series is anchored by R2 as the reference molecule, incorporated a terminal IC‐2F and a central core modified with EDOT bridge. The electronic structure and photoelectric properties of all acceptor molecules were investigated using density functional theory (DFT) and time‐dependent density functional theory (TD‐DFT). Charge transfer matrix (CTM), Density of states (DOS) and Reorganization energy (RE) etc. were analyzed to provide fundamental knowledge on charge transport and electronic excitation. Among the studied molecules, W2 exhibited a smaller energy gap (1.74 eV) compared to the other molecules, effectively transferring its electron from HOMO to LUMO. At the same time, the W2 molecule has excellent Voc and FF. Furthermore, W2 displayed the largest λmax redshift compared to R1. Although W3 had a smaller value of λh, the comprehensive photovoltaic parameters of W2 were more excellent. The research results not only demonstrated the feasibility of introducing different alkoxy groups to alter the structure of the π bridge and central core is a feasible method for constructing high‐performance NFREAs, but also highlighted that BDT cores combined with EDOT bridges are among the most promising small molecule acceptors (SMAs) that could be considered as reasonable candidates for synthesis and incorporation into organic solar cells. The results of this study are expected to provide seminal ideas for the design of high‐performance non‐fullerene acceptors.
Cutaneous Adverse Effects Associated with Lag-3 Inhibitor Use in Cancer Treatment: A Systematic Review
Authors: Ghani Hira , Khan Samavia , Jamgochian Marielle , Richards Beth , DeCecco Erica , Fliorent Rebecca , Cheendalla Nithisha , Khatri Khalil , Rao Babar 
Published: October 2023

Abstract
Immunotherapy has become a mainstay of treatment for many cancers. Multiple immune checkpoint inhibitors have been used to treat malignancies, including anti-programed death-1 (PD1) and anti-cytotoxic T-lymphocyte-associated protein (anti-CTLA4). However, a significant percentage of patients develop resistance to these immunotherapy drugs. Therefore, novel strategies were developed to target other aspects of the immune response. Lymphocyte activation gene-3 (LAG-3) is a cell-surface molecule found on natural killer cells and activated T-cells which negatively regulates T-cell proliferation and function. LAG-3 inhibitors interact with LAG-3 ligands on the surface of T-cells to block T-regulatory (Treg) cell activity, suppress cytokine secretion and restore dysfunctional effector T-cells which subsequently attack and destroy cancer cells. This review reports the dermatologic side effects associated with LAG-3 inhibitors used in the treatment of melanomas. Using PRISMA 2022 guidelines, a comprehensive literature review of PubMed, Google Scholar, Embase, Cochrane, and Web of Science databases was conducted. Three studies were identified that demonstrated that the use of LAG-3 inhibitors, whether as a single agent or in combination with other immune checkpoint inhibitors, resulted in stomatitis, pruritus, rash, dry skin, erythema, and vitiligo. Further research is warranted to assess the cutaneous adverse events observed with LAG-3 inhibitors in treating melanoma and to identify populations most vulnerable to such side effects.
Long‐term effects of experiencing childhood parental death on mental and physical health: A NESDA study
Authors: van Heijningen Carline J. M. , van Berkel Sheila R. , Rosinda Selena J. , Penninx Brenda W. J. H. , Alink Lenneke R. A. , Elzinga Bernet M. 
Published: October 2023

AbstractExperiencing parental death during childhood is an adverse, potentially traumatic experience that may have substantial long‐term effects on mental and physical well‐being. The current study was based on data of the Netherlands Study of Depression and Anxiety to investigate mental health (i.e., depressive symptoms, anxiety symptoms, and suicidal ideation) and physical health outcomes (i.e., metabolic syndrome, telomere length, and perceived physical health) as well as health behaviour (i.e., smoking status, alcohol use, and physical activity) to provide more insight into the long‐term outcomes after experiencing childhood parental death (CPD). For individuals who experienced CPD, we also investigated the role of loss‐related factors in these associations, namely the age of the child when their parent passed away and gender of the deceased parent. Interviews and questionnaires were completed by adults between 18 and 65 years; 177 participants experienced CPD (mean age = 45.19, 61.6% female) and 2463 did not (mean age = 41.38, 66.6% female). Results showed no overall association between the experience of CPD and mental and physical health indices and health behaviour. Within the CPD group, experiencing CPD at a younger age was related to a higher likelihood of suicidal ideation. These findings seem to illustrate a general positive adjustment with regard to long‐term health functioning after experiencing such an impactful life event. Future research should focus on individual differences in terms of adaptation, especially elucidating on contextual factors after the loss, such as the kind of support that is or is not provided by the surviving parent and/or other important individuals.
Recent Advances in the 3D Chiral Plasmonic Nanomaterials
Authors: Liu Wenliang , Han Han , Wang Jiqian 
Published: October 2023

AbstractFrom the view of geometry, chirality is that an object cannot overlap with its mirror image, which has been a fundamental scientific problem in biology and chemistry since the 19th century. Chiral inorganic nanomaterials serve as ideal templates for investigating chiral transfer and amplification mechanisms between molecule and bulk materials, garnering widespread attentions. The chiroptical property of chiral plasmonic nanomaterials is enhanced through localized surface plasmon resonance effects, which exhibits distinctive circular dichroism (CD) response across a wide wavelength range. Recently, 3D chiral plasmonic nanomaterials are becoming a focal research point due to their unique characteristics and planar‐independence. This review provides an overview of recent progresses in 3D chiral plasmonic nanomaterials studies. It begins by discussing the mechanisms of plasmonic enhancement of molecular CD response, following by a detailed presentation of novel classifications of 3D chiral plasmonic nanomaterials. Finally, the applications of 3D chiral nanomaterials such as biology, sensing, chiral catalysis, photology, and other fields have been discussed and prospected. It is hoped that this review will contribute to the flourishing development of 3D chiral nanomaterials.
What Do We Talk About When We Talk About Neuro? A Response to Suzanne Egan
Authors: Wood Julian 
Published: October 2023

AbstractThe following piece addresses some of the issues raised by Suzanne Egan about the growth of neurologically influenced understandings of trauma and trauma-informed practice. The growth of this phenomenon perhaps reflects an increased tendency to see biological understandings (especially brain chemistry and functioning) as primary. Whilst the piece (and Egan’s discussion) does not dismiss this biological element, it nonetheless seeks to interrogate exactly how neurological understandings can dovetail with other disciplines such as those provided by the social sciences. Both pieces address the ideas of discourse and the discursive constructions of problems as explored in the work of both Michel Foucault and Nikolas Rose.
The Power, Passions, and Perils of Identity: On Chantal Mouffe
Authors: Low Remy Y. S. 
Published: October 2023

AbstractIn this chapter, I engage with the work of political theorist Chantal Mouffe that puts forward a malleable and relational understanding of identity beyond simple demographic categories—specifically her account of how political identities are contingently formed through processes of ‘identification’ and ‘antagonism’. Bringing in illustrative vignettes from discussions in a teacher education classroom, as well as some recent neuroscience research, I gesture towards the power of identification and antagonism in fomenting confidence and collective resolve. I also draw from those discussions and sources to raise questions about the potential hazards with such collective identification and antagonism, especially those of us who are committed to education—even of ‘them’ whom ‘we’ are utterly opposed.