bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women’s Domestic Role Based on Islamic Teachings (Classical Fiqih) and Local Culture
Authors: Saiddaeni Saiddaeni 
Published: December 2023

Islam and Feminism, both are perceived as incompatible. However, this view is sadly only generated by the Western when they see Islam in the Middle Eastern. It even misleads when the Western has been only looking for particular countries which practice conservative and textual Islam. In reality, Islam put women in a respectful position, and though Islam has different points of view from some points in feminism, it does not mean they are against each other. Here in this paper, I tried to analyze a comparative study between how our Indonesian culture and how Islamic teachings perceive the role of women in their domestic reality. Here we make structure our paper starting with an introduction, later we talk about classical Fiqih. The reason why we choose classical Fiqih is that we want to understand the root of Islamic teachings on the blatant reality so we can understand how Islam sees a woman in reality. Later, we will discuss a comparison between our culture in general and Islamic Teaching so we will have insight into which one is part of our culture and which one is purely Islamic teachings. From our findings, we found that our culture and Islamic teaching have relatively similar points of view on women’s role in domestic reality. However, the conservative approach is coming from misunderstanding and, people's attitudes to mixing Islamic teachings with their Khawarij culture which is not a real Islam yet because people from outside of the Islamic world do not understand, they tend to think it is a real Islam which is giving Islam a bad reputation.
The biodiversity of helminths of domestic reindeer in the Murmansk region
Authors: Loginova O. A. , Plotnikova Iu. K. 
Published: December 2023

The Murmansk region is an important part of the Russian Arctic Zone, and reindeer husbandry there is one of the leading branches of agriculture, which employs the local population, including indigenous peoples of the North. The success of domestic reindeer husbandry largely depends on the health of the reindeer. Since the previous fundamental study of reindeer infestation with helminths was carried out by Soviet scientists in the mid-twentieth century, there is an urgent need to revise the helminth fauna. Therefore, the aim of our work was to study the biodiversity of helminths of domestic reindeer in the Murmansk region. The study of 31 fresh samples of domestic reindeer (Rangifer tarandus) feces was carried out using complex helminthoscopy methods in accordance with GOST R 54627-2011 “Agricultural ruminant animals. Methods of laboratory helminthology diagnostics”: examination, larvoscopy according to Vajda, flotation ovoscopy according to Darling, sedimentation ovoscopy using the method of successive washings, cultivation of parasitic nematode larvae from their eggs. The intensity of invasion was determined using a VIGIS camera from the “Diapar” kit. Helminths of two classes were discovered: trematodes – the genus Paramphistomum and nematodes – the order Strongylida (in particular, the genus Ostertagia), the genus Dictyocaulus and the species Elaphostrongylus rangiferi. Prevalence rates were: 26% for Paramphistomum, 19% for strongylids, 3% for Dictyocaulus and 52% for E. rangiferi. Helminths were found both on their own and in associations: dictyocaulus + strongylids + paramphistoms, elaphostrongylids + strongylids, elaphostrongylids + paramphistoms. Among the normal larvae of E. rangiferi, there were deformed individuals: with pathological swellings in different parts of their bodies. The intensity of invasion in all cases was low.
The effect of various drugs on the growth rate of sterlet larvae
Authors: Kuzmicheva S. V. , Mikryakov D. V. , Novikov D. A. , Salov S. R. 
Published: December 2023

An experimental study of the effect of various feed additives on the rate of mass accumulation, growth rate and survival of sterlet larvae was carried out. Four groups of fish were planted in flowthrough plastic pools with 150 fish each. The control group (I) was fed without additives, while the experimental group was fed with the addition of different preparations: II - preparation "AQUATAN" based on ellagotannins produced by the company "Tanin", Sevnica, Slovenia. Sevnica (Slovenia) at the rate of 2 g/kg of feed, III - antibacterial preparation based on ciprofloxacin "Antibak-100" (LLC "NVTs Agrovetzaschita"), at the rate of 0.5 g/kg live weight of fish, IV - probiotic based on Bacillus subtilis "SUB-PRO" (LLC "Vector-Euro") at the rate of 100 g/t feed. The preparations were added to the feed according to the instructions. The effect of preparations on fish was evaluated by fishery indicators: average daily growth rate, absolute growth, average daily gain and mass accumulation coefficient. During the experiment it was found that the values of fishery indicators in different groups of sterlet changed with different intensity depending on the time after the beginning of the experiment. The highest growth rate and mass accumulation rates were recorded in fish fed with SUB-PRO and Antibak-100, and the lowest with Aquatan. The results obtained indicate the expediency of further studies of the effect of various preparations on the fishery parameters of aquaculture objects aquaculture.
An immunochromatographic test for the detection of anti-tuberculosis antibodies
Authors: Khammadov N. I. , Khaertynov K. S. , Akhmadeev R. M. , Shangaraev R. I. , Usoltcev K. V. , Khamidullina A. I. , Galeeva A. G. 
Published: December 2023

Tuberculosis is a dangerous socially significant disease of various animal species. According to Rosselkhoznadzor data for 2022, the situation with bovine tuberculosis is endemic, stable, long-term trends are decreasing, epidemic thresholds for ill health and incidence have not been overcome. It should be noted that in 2022, bovine tuberculosis was not officially detected, but this infection was registered in several pigs and wild boars. Take a point that the reduction in the number of cases of tuberculosis in cattle is decreased (to zero), the overall strategy for combating this disease is successful, but this does not mean that the need to develop new tests for the accelerated diagnosis of this infection has completely disappeared. The safety of service personnel directly depends on minimizing the risk of infection with pathogens common to humans and animals, one of which is tuberculosis. The fastest way to indicate infectious agents is by immunochromatographic analysis. This publication is devoted to the details that it is desirable to focus on when developing a diagnostic test based on immunochromatographic analysis, using the example of bovine tuberculosis. As an antigen in the presented study, native antigens of Mycobacterium bovis grown on a nutrient medium Levenshtein-Jensen with proven antigenic activity were used. Conjugation of antispecies antibodies was carried out with a colloidal solution of gold, (diameter of particle is 25±0,9 nm). In the course of the work, the optimal conditions for the manufacture of a diagnostic test for the detection of anti-tuberculosis antibodies by immunochromatographic analysis were shown.
To study the bioequivalence of the drugs Doxitron chewable tablets and Ronaxan when used in dogs
Authors: Komarov A. A. , Engashev S. V. , Selimov R. N. , Mironenko A. V. , Goncharova E. N. , Gabidullina D. E. 
Published: December 2023

A study was carried out to investigate the bioequivalence of the drugs "Doxitron chewable tablets" and "Ronaxan" when administered to dogs. Two groups of animals were formed with 4 dogs in each group. A cross-sectional study design was used for the experiment. Biological material (blood) was sampled before drug administration, and 15, 30, 45 min, 1, 1.5, 2, 3, 4, 6, 8, 8, 10, 24, 30, 48, 72 h after drug administration. In the course of the study the following parameters were controlled: concentrations of the active substance of the preparations in the blood plasma of dogs. The article describes in detail the scheme of the experiment, reagents and standard samples, the process of sample preparation of blood plasma samples and HPLC-MS/MS analysis. The bioequivalence of the preparations "Doxitron chewable tablets" and "Ronaxan" is evaluated. The time to reach the maximum plasma concentration (Tmax) averaged 3.0 h for the investigational drug "Doxitron chewable tablets" and 3.0 h for the reference drug "Ronaxan". The maximum plasma concentration (Cmax) was 4007.4±964.4 ng/ml for the study drug Doxitron Chewable Tablets and 3794.9±1121.5 ng/ml for the reference drug Ronaxan. The 90% confidence intervals of CmaxT/CmaxR and AUC0-tT/AUC0-tR ratios of doxycycline were within the range of 80-125%. The preparations "Doxitron chewable tablets" and "Ronaxan" are bioequivalent.
Architectonics of parenchymal organs of white rats under conditions of induced immunosuppression and the use of Interferon lambda
Authors: Vostroilova G. A. , Khokhlova N. A. , Mikhailov E. V. , Shabanov D. I. , Korchagina A. A. , Nekrasov A. V. , Shabunin B. V. 
Published: December 2023

Violation of the functioning of the organs of the immune system, both in humans and in animals, is due to the influence of unfavorable factors of natural and anthropogenic origin on the body, as well as infectious diseases of various etiologies. The article discusses changes in the architectonics of parenchymal organs of white laboratory rats after exposure to the drug interferon lambda on the background of cyclophosphamide (CF). It was found that modeling of immunosuppression through the use of CF led to a decrease in the number of lymphoid cells and the appearance of foci of accumulation of blast cells and megakaryocytes, which indicates a lesion of lymphoid and hematopoietic tissues. In addition, an immunosuppressive effect on the spleen was revealed, the mass coefficient of which in the group with the use of CF was increased 3.53 times, in the group with the simultaneous use of CF and the drug interferon lambda – 2.75 times relative to the control group. There was also a decrease in the mass coefficient of the thymus by 47.6-50.0% in the same groups, which can be regarded as damage to the organs of the immune system. The negative effect of CF on the spleen was confirmed by histological examination. Thus, when inducing immunosuppression, the loss of white pulp was 73.0-77.5% relative to the group of control animals, which is 20.0% higher than in rats treated with interferon lambda, which may indicate a positive immunotropic effect of the drug under study. In addition, no significant morphological changes were detected when the body of healthy rats was exposed to interferon lambda in the studied organs, the morphological picture is similar to that of intact animals, which may indicate the safety of its use to animals.
Indicators of uterine contractile activity in highly productive sows using supraphysiological doses of oxytocin
Authors: Filatov A. V. , Minin A. V. 
Published: December 2023

The use of large doses of oxytocin to sows in the early postpartum period is indicated to normalize lactogenesis, increase immune proteins in colostrum and transitional milk, prevent postpartum complications, and increase the viability of the offspring. However, the effect of these doses of myotropic drug on the contractile activity of the uterus is not shown. The aim of the work was to study the contractile function of the uterus of highly productive sows in the early postpartum period and the peculiarities of its reaction to supraphysiological doses of oxytocin. Scientific and production experience was carried out on the basis of a large pig breeding complex. The object of the study was highly productive sows 16 hours after the completion of normal labor. The hormonal drug oxytocin was administered intra-muscularly to animals at a supraphysiological dose of 75 units. Hysterograms of uterine contractions were recorded by internal hysterography before and immediately after administration of the myotropic drug, as well as one hour after injection. On hysterograms, spontaneous contractile activity of the uterus in highly productive sows was characterized by regular, short-term contractions of the optimal amplitude. Activation of the contractile function of the myometrium occurs 5-7 minutes after injection of the drug. After administration of oxytocin, an increase in the amplitude of contraction of uterine smooth muscle cells was noted by 39.17% (p<0.05), while a longer period of contractions was recorded by 31.64%. The frequency of uterine contractions increased 2.0 times (p<0.01). The contract index was significantly 3.66 times (p<0.05) higher than that in relation to the initial level. After 1 hour after oxytocin administration, an increase in the contraction period by 5.42% was noted, with a decrease in amplitude by 37.87% (p<0.01) and the number of contractions by 49.91% (p<0.01), the contractional index decreased by 3.05 times (p<0.01) relative to the previous level. In relation to the initial level, the contract index was 20.0% higher. At the same time, an increase in the duration of contractions by 38.78% and a decrease in their amplitude by 13.53% were noted. Consequently, oxytocin at a dose of 75 ME not violate the contractile ability of the myometrium. The response of the smooth muscle cells of the uterus to the supraphysiological dose of oxytocin is maximally manifested in the first hour after the administration of the myotropic drug.
Elimination of 1,3,7-trimethylxanthine in laboratory animals during the induction of fatty hepatosis
Authors: Popova O. S. , Ponamarev V. S. , Kostrova A. V. , Agafonova L. A. 
Published: December 2023

Liver pathologies play a significant role in changing the metabolism and clearance of a number of pharmacologically active substances, including 1,3,7-trimethylxanthine, which is explained by their influence on enzyme systems that regulate the biotransformation of exogenous biologically active substances. Currently, changes in caffeine clearance are being actively studied in various hepatobiliary disorders, especially those that are chronic, since it is precisely such pathologies, according to a number of researchers, that are characterized by the most predictable and stable change in the trimethylxanthine pharmacokinetic profile. The purpose of the study was to determine changes in serum caffeine levels when inducing fatty liver disease in laboratory animals (rats). The studies were carried out in the vivarium of the Department of Pharmacology and Toxicology of the Federal State Budgetary Educational Institution of Higher Education of St. Petersburg State University of Medicine. Laboratory animals from a previous series of experiments were selected for the study in order to further compare the “caffeine curves.” Fatty hepatosis was modeled using strontium sulfate according to the methodology developed at the Department of Pharmacology and Toxicology. Upon completion of induction, fatty hepatosis was confirmed based on clinical and biochemical signs. Based on the studies conducted, we can conclude that there are certain correlations. For example, in fatty hepatosis, the elimination of caffeine is not significantly slowed down with a characteristic long plateau (up to 8 hours after administration), turning into a smooth decrease in concentration. Experimental data can be used to create a database to assess the relationship between pharmacokinetics and the physiological state of animals. Similar experiments need to be carried out on other animal species, which will create a holistic picture and help in assessing pathologies for veterinary specialists.
The effect of liposomal feed additives on the provision of vitamin A and carotene in cows
Authors: Khomenko R. M. , Alexandrov V. V. , Safronov S. L. 
Published: December 2023

In conditions of industrial milk production, it is important to provide livestock with complete feed, including all the necessary nutrients to meet the needs of a lactating cow. Active metabolic processes and intense activity of the cow’s entire body during lactation are a prerequisite for increasing its need for vitamins. Currently, various feed additives and premixes are used in feeding dairy cows, enriching the animals’ diet with essential vitamins, but their productive effect is contradictory. The conducted studies established the positive effect of the liposomal additive “LipoCar” on meeting the need for β-carotene and vitamin A in the body of cows during lactation. Introduction of the feed additive “LipoCar” into the main diet in the amount of 6 g/cow/day. helps normalize the vitamin nutrition of cows, especially during the transit period. This is confirmed by the results of studies of the blood serum of cows before and after the use of the LipoCar feed additive. In the control group, the content of vitamin A in the blood serum of cows was 2.4 times higher and corresponded to the physiological norm, compared to the control group, where this indicator did not correspond to the norm. There was a positive trend in the content of β-carotene in the blood serum of cows in the experimental group, with an increase of 4.4 times by the end of the study compared to the control group. The results obtained allow us to recommend the use of the LipoCar feed additive in the diets of cows from the first day after calving in an amount of 6 g/head. 1 time per day for 30 days to normalize metabolism and increase resistance in lactating cow.
Morphological examination of the isthmus of the oviduct in the cross Hysex white chicken
Authors: Dikikh A. A. , Fomenko L. B. , Pervenetskaya M. V. 
Published: December 2023

The reproductive function of birds and the hatchability of eggs are one of the most important and determining factors in raising poultry, and depend on a number of not only genetic, physiological, environmental, but also morphological factors. The main goal of this article is to identify the features of the macro- and microscopic structure of the isthmus of the oviduct in a Highsex white cross chicken. The object of the study is the oviduct of a Highsex white cross chicken at the age of 180 days. For histological examination, the material was fixed in a 10% aqueous solution of neutral formaldehyde, followed by embedding in paraffin. The research materials were subjected to statistical processing using the STATISTICA 6.1 program. As a result of our research, we noted that the isthmus of the oviduct is located between the albumen section and the bird's uterus and has a small diameter, representing a narrow strip of tissue (translucent zone) with the presence of tubular glands. The mucous membrane of the isthmus is lined with multirow ciliated epithelium. Between the primary folds there are deep crypts, which with their base are embedded deep into the lamina propria; they contain many branched glands that open into ducts onto the surface of the mucous membrane. In the subepithelial layer of the lamina propria, fibers of loose connective tissue are located, tightly surrounding the branched tubular glands. The mucous membrane of the isthmus occupies 59.74% of the total thickness of the isthmus. Muscular membrane – 29.16%. While the serous membrane accounts for 11.1% of the total thickness of the isthmus wall. The mucous membrane of the isthmus, due to the active secretory function of the glands, is 2 times the thickness of the muscular layer.
Lipid composition of plasma membranes of rooster sperm (Gallus gallus domesticus) and its dynamics during cryopreservation
Authors: Stanishevskaya O. I. , Silyukova Y. L. 
Published: December 2023

The structural features of the plasma membranes of avian sperm make them more sensitive, compared to those of mammals, to low-temperature stress. The qualitative and quantitative composition of membrane lipids can become a determining factor in the development of new effective compositions of cryoprotective media. The purpose of the study was to determine the lipid composition of the plasma membranes of native rooster sperm, the content of carbohydrates and polyols in their cytosol, as well as dynamic changes in the membrane lipidome and cytosol composition under the influence of the cryopreservation protocol, depending on the composition of the cryoprotective medium. The studies were carried out on Rhode Island roosters (n=10), the total and progressive sperm motility and membrane damage were determined. Semen freezing and thawing was carried out using fast protocols. To determine the lipid composition of the plasma membranes of sperm and the composition of their cytosol, a chromatographic analysis method was used. The following were identified in the membranes of native spermatozoa: phospholipids, glycolyllipids and neutral lipids, represented by phosphatidylethalamine, phosphatidylserine, phosphatidylcholine, sphingomyelin and sterol. A change in the ratio between membrane lipids of the inner and outer layers of the plasma membrane of rooster spermatozoa under the influence of the cryopreservation protocol was shown. In native spermftozoa this ratio was 41.2% and 39.4%, respectively, in thawed sperm when using the LCM-control medium – 38.3% and 47.2%, respectively, when using the LCM-T20 medium - 40.7% and 44.5%, respectively. There was a significant decrease, more than 3 times, in the total amount of carbohydrates (fructose, glucose, trehalose) and polyols (glycerol, mannitol, inositol) in the cytosol of frozen/thawed spermatozoa when using the cryoprotective medium LCM-control compared with the values of the native spermatozoa - 0 .1145 mg/ml and 0.0360 mg/ml, respectively. When using the LCM-T20 medium, the change was insignificant and the delta was 5.2%. The effectiveness of using cryoprotective medium LCM-T20 containing trehalose has been proven to maintain the lipid membrane architecture of rooster spermatozoa, the carbohydratepolyol composition of their cytosol and, as a consequence, the morphofunctional usefulness of gametes during the freezing/thawing process.
Evaluation of the possibility of using indicators of the blood coagulation system of cows to predict late toxicosis of pregnant women
Authors: Mikhalev V. I. , Chusova G. G. 
Published: December 2023

Indicators of the blood coagulation system (thrombin time, prothrombin time, activated partial thromboplastin time - aPTT) were studied on 42 pregnant cows at 60-75, 135-150 and 210-230 days of pregnancy, divided according to the principle of analogues into three groups: physiological course, fetal growth restriction syndrome without late toxicosis of pregnancy, fetal growth restriction syndrome complicated by gestosis. Pregnancy was diagnosed using transrectal and ultrasound examinations. Fetal growth restriction syndrome was diagnosed at 60-75 days of pregnancy using an ultrasound scanner with a linear sensor with a frequency of 7.5 MHz. Late toxicosis of pregnant animals was diagnosed at 210-230 days of pregnancy by the presence of hypertension, proteinuria and edema. Blood samples were taken from the animals included in the experiment to determine the platelet content, thrombin and prothrombin time and aPTT. It has been established that platelet content is an informative indicator for predicting gestosis in the first five months of pregnancy with a sensitivity of 80.0% and specificity of 87.5%. The sensitivity of thrombin time at 60-150 days of pregnancy is 77.8%, specificity - 90.0%, prothrombin time - 70.0 and 88.9%, aPTT at 135-150 days of pregnancy - 77.8 and 85.7%, respectively. Prognostic markers for early diagnosis of late toxicosis in pregnant animals, determined at 2 months of pregnancy are: platelet level - 451.2 x 109/L and higher; thrombin time – 87.3 seconds and below; prothrombin time – 35.1 seconds and below. Indicators for early diagnosis of gestosis, determined at 5 months of pregnancy, are: platelet level - 437.5 x 109/L and higher; thrombin time – 78.6 seconds and below; prothrombin time – 30.3 seconds and below; aPTT – 41.8 sec and below.