bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of polymeric IPN hydrogels by free radical polymerization technique for extended release of letrozole: Characterization and toxicity evaluation
Authors: Yousaf Hammad , Khalid Ikrima , Barkat Kashif , Mehmood Yasir , Badshah Syed Faisal , Anjum Irfan , Nafidi Hiba-Allah , Bin Jardan Yousef A. , Bourhia Mohammed 
Published: November 2023

Abstract
This research study’s objective was to formulate interpenetrating pH-sensitive polymeric networks interpenetrating networks (IPNs) based on hydroxypropylmethylcellulose (HPMC)/Primojel for use in the treatment of various malignant conditions. For controlled release, letrozole (LTZ) was selected as a model drug in HPMC and Primojel-based IPN hydrogels. HPMC and Primojel based IPN hydrogels were fabricated through the free radical polymerization method by utilizing HPMC and Primojel as polymers, methacrylic acid as monomer, ammonium persulfate as initiator, and methylenebisacrylamide as cross-linker. For structural characterization, various techniques such as Fourier transform infrared spectroscopy, Scanning electron microscopy (SEM), DSC, TGA, and Powder x-ray diffraction (PXRD) were applied to IPN samples. In vitro and swelling studies were also employed to observe the response of these polymeric networks against 1.2 and 7.4 pH. TGA and DSC of an optimized loaded formulation possess better thermal stability as compared to individual drug. PXRD depicted minor crystallinity and a significant amorphous nature. SEM images show that polymeric networks possess an uneven and porous surface. Significant swelling and enhanced in-vitro outcomes at a high pH of 7.4 confirmed the IPN pH responsive properties. Toxicological studies performed on rabbits revealed no harm in the results. Thus, IPN based on HPMC/Primojel was successfully synthesized and can be used for LTZ’s controlled release.
Radial cracks in Castanopsis hystrix wood and its dimensional stability improvement by resin-impregnated modification
Authors: Meng Surong , Su Yingying , Huang Anmin , Sun Bailing 
Published: November 2023

Abstract
This study investigated the characteristics of radial cracks in Castanopsis hystrix wood and evaluated its dimensional stability after impregnation with low-molecular-weight polyacrylate (PA), melamine-urea-glyoxal (MUG), and melamine-urea-formaldehyde (MUF) resins. The physical properties were examined by dimensional stability measurements, dynamic vapor sorption (DVS) analysis, and scanning electron microscopy (SEM). The results showed that radial cracks were easily produced in the transverse section of untreated wood during drying. The surfaces of the radial cracks exhibited an even and clean structure without fluffs on the pair of surfaces, and cracks spanned 4–5 annual rings. The resin-impregnated wood showed no radial cracks on its transverse surface. C. hystrix wood modified with MUG and MUF exhibited a higher weight percentage gain (WPG) than wood modified with the same concentration of PA resin. The resin-impregnated C. hystrix wood also showed reduced anisotropy and improved dimensional stability. The SEM images of the modified wood showed that the wood pits and cells were filled with resin, while the cell wall surfaces were covered with a layer of resin.
Animals as Offerings: Faunal Remains from the Carthage tophet
Authors: Fulton Deirdre N. , Hesse Paula , Burns Peter 
Published: November 2023

Abstract
The non-human animal remains excavated in the Carthage tophet represent a substantial sample of animal bones from a single site. The urns contain partial or whole sheep or goat (ovicaprids) carcasses in abundant numbers, revealing a consistent offering of ovicaprids, some birds, and in a very few cases, fish. Overwhelmingly, the animals are whole-burnt offerings, sacrificed as an offering to the deity or deities. The consistency of the age of the cremated ovicaprids that were interred in the urns allows for a profile of relating animal remains to ritual behavior that took place at the Carthage tophet.
When the alienability contrast fails to surface in adnominal possession: bound nouns in Harakmbut
Authors: Van linden An 
Published: November 2023

Abstract
This article investigates the nature and behavior of independent, bound and deverbal nouns at various levels of linguistic organization in Harakmbut (isolate, Peru), and assesses the explanatory potential of the alienability contrast for the data observed. While the distinction between bound and independent nouns is to a great extent motivated by the conceptual distinction between inalienably and alienably possessed items, the behavior of bound and independent nouns in adnominal possession is not. Whereas independent (and deverbal) nouns use a genitive-marked two-word construction, bound nouns can use the same one, when keeping their noun prefix, or they can use a genitive-marked one-word construction, in which they drop their prefix. It is thus argued that there is no alienability split in adnominal possession, that is, there is no coding split according to which bound nouns behave fully differently from independent nouns. This is supported by the finding that bound nouns (unlike independent and deverbal ones) also show the same choice between a two-word and a one-word coding strategy in non-possessive adnominal modification. In noun-noun compounding, the data merely reveal different preferences of bound and independent nouns for the N1 versus N2 position; here deverbal nouns behave identically to bound nouns in dropping their prefix in N2. In noun incorporation, finally, the relevance of the alienability contrast is similar to that for the two-way noun class system. Inalienable semantics (and morphological boundness) could be argued to determine the incorporability of nouns, but there are also exceptions.
From Star Trek to The Hunger Games: emblem gestures in science fiction and their uptake in popular culture
Authors: Freestone Peta M. , Kruk Jessica , Gawne Lauren 
Published: November 2023

Abstract
Research on emblems to date has not drawn on corpus methods that use public data. In this paper, we use corpus methods to explore the use of original fictional gestures in the real world. We look at two examples from popular science fiction, the Vulcan salute from Star Trek and the three-finger salute from The Hunger Games. First, a Twitter corpus of the Vulcan salute emoji shows that it is used to represent Star Trek fandom and wider nerd culture, alongside its use as a greeting. Second, a global news corpus shows the three-finger salute has come to be used as a pro-democracy protest gesture across political and cultural boundaries in South East Asia. These corpus studies show different trajectories for the two gestures, with the three-finger salute escaping the confines of its fictional world, while the Vulcan salute has come to stand in as a reference to the media it originated from. We conclude with a reflection on the opportunities, challenges, and limitations of bringing corpus methods to gesture studies.
Rote Rosen, rote Lippen, roter Wein revisited
Authors: Forell Marina 
Published: November 2023

Abstract
The relationship between Germany and Italy is a special one, as Italy was already a place of longing in Goetheʼs time and became so even more in the 1950s post-war period, with the first travel abroad, interest in the new guest workers and the general desire for everything non-German. Italy thus became a very important place of the imagination in the Schlager-songs of West Germany: in addition to specifically German and Alpine themes, Italian subjects in particular can be found at this time and in this genre. The foundation for these attitudes, as this essay will show, lie in the approaches to Italy developed in the 19th century, based in part on escapism and exoticism. Even today, alongside pop and rock artists whose production functions differently, one German-Italian showmaster in particular still plays heavily with clichés but also with irony, as this essay will demonstrate. Through his staging, he implies that these patterns and paradigms are not yet completely obsolete.
Strukturbrüche
Authors: Döpking Lars 
Published: November 2023

Abstract
Since the end of the 1980s, Italian capitalism has been struggling. Low growth rates, increasing inequalities and relative impoverishment are compromising the pursuit of happiness and fuelling political discontent. Against this background of crumbling economic and social structures, the article explores historical and sociological perspectives on Italian capitalism’s contemporary dynamics. To this end, it first summarises some central lines of development and then maps existing explanatory approaches onto them. Third, it discusses what a historical contribution to these debates might look like. Finally, it recalls the promise of the Italian case within theoretical debates centred on the political economy of modernity.
Cloning andin silicoinvestigation of a putative voltage-gated calcium channel gene and protein inAstacus leptodactylus
Authors: Saglam Berk , Ergin Bora , Beyatli Nazlı Coskun , Arslan Kaan , Bastug Turgut , Purali Nuhan 
Published: November 2023

AbstractObjectivesVoltage-gated calcium channels are essential elements in development of many cellular processes like electrical signaling, contraction secretion and gene expression. There has been a fair amount of information about the functional and structural properties of the calcium channels in mammalian species. Crayfish serves as a model animal for many types of experiments. However, there has been no information related to the molecular and genetic properties of the calcium channels in the crayfish.MethodsConventional cloning methods, three-dimensional structural calculations, docking experiments have been conducted.ResultsAn mRNA 7,791 bp in size has been cloned. The coding region has been translated into an alpha peptide with 1,942 residues. The cloned protein sequence has similarity to other L-type voltage-gated calcium channel sequences from the neighboring species. Three-dimensional structure, in reference to human L-type voltage-gated calcium channel, has been calculated. Known calcium channel blockers, nifedipine, verapamil and diltiazem have been successfully docked on the calculated three-dimensional model.ConclusionsConsidering the similarity assay in the National Center for Biotechnology Information (NCBI) platform, the three-dimensional structural calculations and the docking experiments it was concluded that the cloned mRNA codes an alpha peptide for a putative voltage-gated calcium channel protein in the crayfish. In the present work by using the conventional molecular biology methods a complete mRNA coding a putative calcium channel has beende novocloned. Three-dimensional structure of the related protein has been calculated and several pharmacological agents blocking the channel have been docked to the identified receptor sites.
Types and Contributors to Occupational Fatigue
Authors: Marvin Graham , Schram Ben , Orr Robin , Canetti Elisa F. D. 
Published: November 2023

ABSTRACTAlthough fatigue is commonly experienced in many highly demanding occupations (e.g., military, first responders, etc.), it is poorly defined. Fatigue can strongly affect occupational performance by negatively influencing the ability to interact with the world by altering the capacity to think, move, feel, see, and speak. The first step in fatigue risk management strategies is to establish a context. The context of this narrative review is to specifically describe and discuss the 6 overarching types of occupational fatigue: cognitive, physical, burnout, emotional, visual, and vocal fatigue, and how each affects varying occupations. Furthermore, fatigue type can be influenced by several intrinsic factors, such as sleep deprivation, circadian alignment, ultradian process, sleep homeostasis, and health factors. Similarly, extrinsic factors influence fatigue, such as workload, shift work, and environmental issues. Understanding the types and contributors to occupational fatigue may help clarify the context of occupational fatigue and serve to guide future occupational fatigue management.
Assortative mating in Gastropoda: A meta-analysis
Authors: Kramarenko S. S. , Kramarenko A. S. 
Published: November 2023

The term ‘assortative mating’ denotes situations when the choice of a mating partner is nonrandom and the phenotypes across mate pairs are correlated, either positively or negatively. Assortative mating has been registered as a particular type of behaviour in many taxa of animals, including various vertebrate and invertebrate species. The aim of this study is to conduct a meta-analysis of published data concerning assortative mating in various taxa of Gastropoda. In total, we found 36 published peer-reviewed papers that consider the size-assortative mating in Gastropoda. 32 species belonging to different taxonomic groups of this class were studied, which provided 58 cases for further analysis. The range of estimates of the strength of assortment between individuals for species included into our meta-analysis (46 cases) is very wide: from –0.155 (Brephulopsis cylindrica) to +0.966 (Veronicella sloanii). Integrally, for the studied species of Gastropoda, the average weighted estimate of the strength of assortment between the sizes of copulating individuals was 0.381 ± 0.014. It revealed that virtually all the points representing individual studies form a funnel-shaped dispersion on a scatterplot that lies along the line representing the estimate of the generalized mean rgen = 0.343 and uniformly fill the funnel-shaped space between the lines of 95% confidence interval of the correlation coefficient for a given sample size adjusted for the overall mean. The distribution of the estimates of the correlation coefficient between copulating individuals among the various gastropod species has a shape close to the normal distribution (Kolmogorov-Smirnov's d = 0.061; P > 0.20). Moreover, most estimates are concentrated within a range from 0.2 to 0.6. We found that the probability of obtaining reliable estimates of the correlation coefficient between the sizes of copulating individuals is dependent upon the number of pairs used in the analysis (binary logistic regression: χ2 = 8.92; df = 1; P = 0.0028). It can be argued that the existence of the negative size-assortative mating in Gastropoda has not yet been proved. On the other hand, if only statistically significant cases of size-assortative mating are considered (37 cases out of 58, or 63.7%), the average weighted estimate of the strength of assortment between sizes of copulating mollusks is 0.439 ± 0.015 (95% confidence interval: 0.409–0.468). If we consider the mating system and the environment simultaneously, the positive size-assortativity is most pronounced among the gonochoristic snails living in the aquatic environment (0.448 ± 0.021) while among the aquatic hermaphroditic species it is the weakest (0.315 ± 0.028). Terrestrial hermaphrodites (land snails and slugs) take the middle position. The numerous examples of the assortative mating with respect to different morphological traits, either quantitative or qualitative, have been described in various species of aquatic and land snails.
The effect on the organism of rats of adding Helichrysum arenarium inflorescences to a hypercaloric diet, high in sugar and fat
Authors: Lieshchova M. A. , Brygadyrenko V. V. 
Published: November 2023

Obesity increases the risk of developing various pathological conditions such as metabolic syndrome, type 2 diabetes, non-alcoholic fatty liver disease, and cardiovascular disease. For mild correction and even treatment of obesity, drugs based on medicinal plants are increasingly being used. This work aims to determine the overall effect of Helichrysum arenarium inflorescences on physiological activity and metabolic processes in model animals fed a diet rich in fat and carbohydrates. In a 27-day experiment on 18 laboratory rats fed a diet with high-fat content and 20% fructose solution, we determined the effect of 0.4% and 4.0% dry inflorescences of H. arenarium from the feed mass on the animals' physiological activity and metabolic processes. The body weight of rats in the control group reached 121.7% of the initial body weight; when consuming 0.4% and 4.0% H. arenarium in the diet, this indicator was lower – 109.6% and 111.2%, respectively. Dry inflorescences of H. arenarium in the rats’ diet at a dose of 0.4% caused a decrease in the relative mass of the heart and thymus and an increase in the relative mass of the caecum and colon. A diet with the addition of H. arenarium caused a change in blood biochemical parameters: an increase in the urea concentration and urea nitrogen, and a decrease in the glucose concentration and protein coefficient. Helichrysum arenarium at both concentrations significantly increased the gamma-glutamyltransferase and alkaline phosphatase activity with a decrease in alpha-amylase activity in the blood. A 0.4% dose of inflorescences of the food mass caused a decrease in AST activity, and 200 g sharply increased blood ALT activity. The consumption of dried H. arenarium inflorescences decreased hematocrit, haemoglobin concentration, erythrocyte and platelet counts, and increased the percentage of eosinophils and monocytes. A decrease in physical activity and an intensification of emotional state were found in the animals after eating dry inflorescences of H. arenarium, regardless of the dose compared with the control group of animals. Significant changes in the orientation activity of the animals were not observed. The obtained results show that adding dry H. arenarium inflorescences as a food supplement to a high-calorie diet is safe, does not cause pathological changes and side effects, and significantly affects metabolic processes. This provides theoretical support for the use of dried H. arenarium inflorescences for the production of nutraceutical and pharmacological products for the correction of metabolic disorders in humans and animals. The doses and duration of their use require further research.
Elm (Ulmus) leaf miners in North-East Kazakhstan
Authors: Zhussip M. , Akhmetov K. , Burkitbaeva U. 
Published: November 2023

Leaf miners are increasingly causing damage to plants, often causing their death. There are about 10 thousand species of leaf miners in the world. The purpose of this study is to establish the location, species diversity, as well as the degree of damage caused by leaf miners to the leaves of Ulmus L. genus trees in the Pavlodar Region. In the course of the study, a visual inspection of the affected areas was used, as well as the selection, drying of damaged foliage and, subsequently, the removal of larvae and adult insects from it, followed by their study. During the vegetation seasons in 2019–2022, in Pavlodar, Ekibastuz and Aksu cities, as well as in Zhelezinka and Koktobe villages, elm leaves were studied for the presence of leaf miners, a visual inspection of the damage locations was conducted, and samples were taken, which later became the material for growing and detailed study of insects at different development stages. The article considers phyllophagous insects mining elm leaves in the North-East of Kazakhstan (Pavlodar Region) in 2019–2022. In the course of the conducted studies on the territory of the Pavlodar Region, 8 species belonging to 5 genera were identified: Stigmella Schrank, 1802, Orchestes Illiger, 1798, Fenusa Leach, 1817, Bucculatrix Zeller, 1839 and Phyllonorycter Hubner, 1822. Leaf miners that belong to the Agromyza genus of the Agromyzidae family were also identified. All representatives are obligate leaf miners, developing at the larval stage in the mesophyll of elm leaves. Most of the leaf-mining insects are represented by Agromyza and Stigmella species. They are among the most dangerous for the biocoenosis of the Pavlodar Region. Moreover, Agromyza insects have high plasticity and may become a problem in other regions. The obtained data will help to contribute to further studies in this direction, and also show the development degree of an understudied problem: the influence of leaf miners on the nature of Kazakhstan.
In operando neutron imaging characterizations of all-solid-state batteries
Authors: Cao Daxian , Zhang Yuxuan , Ji Tongtai , Zhu Hongli 
Published: November 2023

AbstractThe surge in electric vehicle demand has propagated the extensive application of lithium-ion batteries (LIBs) in recent years. Gaining significant traction due to their promising high-energy density and elevated safety over traditional LIBs, all-solid-state Li batteries (ASLBs) have nonetheless been faced with hurdles relating to battery performance. These include concerns with interfacial compatibility, structural stability, Li dendrite inhibition, and large-scale manufacturing. To tackle these issues, it is necessary to employ advanced characterization methods to comprehend the intrinsic mechanisms within ASLBs. In this article, we advocate for the use of neutron imaging as a nondestructive approach for the operando visualization of ASLBs. We draw comparisons with other operando visualization strategies, underline the benefits of neutron imaging, and discuss its potential applicability in the scrutiny of all-solid-state Li metal batteries and all-solid-state Li-sulfur batteries. Neutron imaging provides valuable insights into the dynamics of Li concentration, reaction mechanisms, and transport constraints in ASLBs. These insights are pivotal in contributing to the evolution of high-performance all-solid-state batteries.
Graphical abstract
This article discusses the application of neutron imaging for operando characterization of all-solid-state batteries. It compares neutron imaging to other techniques and highlights its advantages in visualizing light elements such as lithium. It also covers recent progress in using neutron imaging to investigate reaction mechanisms, lithium dynamics, and failure modes in all-solid-state lithium metal and lithium sulfur batteries. It also analyzes the future outlook for neutron imaging as a powerful nondestructive tool to gain insights into interfacial phenomena in all-solid-state batteries.