bluuebunny/crossref_metadata_2025_split huggingface dataset:
Successful Rate of Glaucoma Surgery in Secondary Glaucoma after Vitrectomy in Kariadi General Hospital Semarang 2020-2022
Authors: Ismail Nur Azizah Intan Putri , Maharani  , Rahmi Fifin L. , Puspasari Denti 
Published: February 2024

Introduction & ObjectivesGlaucoma is one of the most frequent complications of vitrectomy surgery. It can cause a significantrise in intraocular pressure (IOP). Glaucoma surgery can be planned in medically uncontrolledglaucoma. Trabeculectomy and Glaucoma Drainage Device (GDD) implantation are the mostfrequent filtering surgeries used in these cases. This study aims to define the success rate ofglaucoma surgery in secondary glaucoma after vitrectomy.
MethodsThis study is an analytical observational study with retrospective data collection held from medicalrecords of patients with secondary glaucoma after vitrectomy who underwent glaucoma surgery inKariadi General Hospital Semarang from 2020-2022. Surgical success defined by postoperative IOPreduced by>20% from baseline, with or without anti-glaucoma medication.
ResultsThere were 16 eyes of trabeculectomy with 5-fluorouracil (5-FU), and 8 eyes of GDD implants. Themean preoperative IOP was 43.76+6.77 mmhg for trabeculectomy 5-FU, and 42.43+4.02 mmhg forGDD implant. IOP levels in both groups varied significantly after one day, one week, one month, andthree months after surgery (p<0.05). The success rate for the trabeculectomy 5-FU group was81.25% and the GDD implant group was 87.5% in 3 months. There was no statistically significantdifference in the success rate between the trabeculectomy 5-FU and GDD implant groups (p=0.839).The complication for the GDD implant group was 25%. No complications were found in thetrabeculectomy 5-FU group.
ConclusionThere was no significant difference in the success rate between trabeculectomy 5-FU and the GDDimplant group. Both groups are viable for glaucoma surgery in secondary glaucoma after vitrectomysurgery.
Management of Recurrent Entropion in Traumatic Proptosis
Authors: ANGGA KARTIWA  , George Raden Mas Said  , Niluh Putu Ayu Dewi Wardhani  , Shanti Fitrianti Boesoirie  , Mohamad Rinaldi Dahlan  
Published: February 2024

Introduction : Shortening of posterior lamella due to fibrotic tissue is the pathomechanism of cicactricial entropion. It may be complicated by proptosis in a post traumatic patient which may require repeated repair procedure.
Case Illustration : A 29-year-old woman came with complaints of protruding left eye since being hit by an iron tip 2 months prior. She also complained off double vision. Left eye presenting visual acuity was 0.08 with hipotropic position, proptosis, lid retraction, and entropion of the inferior lid. CT scan examination showed unremarkable results. The patient then underwent forced duction test, exploration, and muscle restriction release on the left eye, followed by inferior rectus recess and superior rectus resect procedures 3 months later. A month later the patient underwent entropion repair in the left eye using the tarsal fracture method. However, a week later the patient complained of a recurrent entropion, thus a grey line splitting procedure combined with retractor repositioning and tightening of the tarsus was performed. At the 7 days follow-up time, the eyelid margin was succesfully everted with an acceptable result.
Discussion : Skin graft procedure is one of the option for cicatricial entropion. However, its risk of recurrences and more difficult secondary repair can be harrowing. Thus, a grey line splitting procedure is an alternative that can be considered.
Conclusion : Combined procedure of grey line splitting, retractor repositioning, and posterior lamellar tightening showed a good cosmetic result in an uncommon case of entropion.
The Association between Atrial Fibrillation and Central Retinal Artery Occlusion: A Meta-Analysis and Systematic Review
Authors: Yufilia Suci Amelia  
Published: February 2024

Abstract
Introduction & Objectives : Central retinal artery occlusion (CRAO) is a condition where the central retinal artery is blocked. Atrial Fibrillation (AF) is commonly associated with retinal embolism that originates anywhere between the heart and the ophthalmic artery. This study aims to explore the incidence of AF in CRAO.
Methods : A systematic search was performed in three databases: Pubmed, EBSCO host, and Proquest. Newcastle-Ottawa Scale was used to assess the risk of bias in the study included.
Results : Our systematic review comprises six studies, 4 studies included CRAO patients as the study population and AF as the endpoint, and the others 2 studies with CRAO as the endpoint. Meta- analysis of the first group resulted in a significantly favorable AF incident after CRAO with an odds ratio (OR) of 1.46 (95% CI 1.17-1.81, p=0.0007). The second meta-analysis supports CRAO with an OR of 4.86 (95% CI 2.30-10.28, p<0.0001).
Conclusion : It is crucial to identify AF in preventing ocular infarction. This study revealed that AF was identified as a risk factor in patients with CRAO and vice versa.
Detecting Keratoconus in Primary Healthcare: What general practitioners could do?
Authors: Akbar Muhammad Khalil , Samira Cut Putri 
Published: February 2024

Introduction : Keratoconus (KC) is a rare eye disorder that causes corneal thinning and visual disturbances. KC prevalence in the pediatric population is 0.16%. Children with keratoconus experience faster disease progression and significant visual impairment at diagnosis, impacting their quality of life. This case report aims to raise awareness and provide knowledge regarding KC for general practitioners.
Case Illustration : A 14-year-old male visited a primary healthcare facility complaining of difficulty seeing words on the classroom board for the past year. His best-corrected visual acuity was 6/15 (S-10.25 C-5.25x30) OD and 6/60 (S-25.00 C-2.75x150) OS. Upon examination, it was observed that the left cornea was more protruding than the right, with a positive Rizzuti and Munson sign. Based on the findings, the patient was suspected of having keratoconus with amblyopia and was referred to an ophthalmologist for further examination and management.
Discussion : Keratoconus is severe and burdensome to society, impacting children's education and quality of life. Early detection and intervention are crucial to prevent worsening. KC can be detected in primary healthcare by observing external signs such as Rizzuti and Munson. KC can lead to severe vision problems and even amblyopia if left untreated. Treating pediatric KC involves improving vision using contact lenses. In cases where contact lenses cannot be used, keratoplasty may be necessary.
Conclusion : Primary healthcare providers can identify and assess keratoconus in patients and make referrals to ophthalmologists for treatment to minimize the impact on vision and stop its progression.
Different Retinopathy of Prematurity Severity, Onset Therapy and Outcomes in Triplet Babies: A Case Report
Authors: PUTU ANINDYA AGRASIDI  , I WAYAN EKA SUTYAWAN  , NI MADE AYU SURASMIATI  
Published: February 2024

Introduction : Retinopathy of prematurity (ROP) is a vasoproliferative disease of the premature infants, characterized by abnormal vascularization at the junction of vascular and avascular retina. Intravitreal anti-VEGF injection is one of promising management of ROP. The aim is to present the therapy outcomes of triplet babies with different severity and onset therapy.
Case Illustration : This case shows ROP in triplets born at 25-26 weeks gestational age. First baby, weighed 630 g with Bilateral Stage 2 Zone II Posterior with Plus Disease treated with intravitreal ranibizumab injection at 11 weeks (PMA 36-37 weeks). Second baby, weighed 620 g and get bilateral intravitreal ranibizumab injection a week after first baby, left eye got worse on first week, but getting better on the last follow up. Third Baby, weighed 750 g with bilateral Stage 3 Zone I with Plus Disease (worst eye condition), but because he had worst general condition, so the latest got screening, got no intervention. Two babies were treated with anti-VEGF therapy – bevacizumab. All babies has outcome regression, no recurrence of ROP in those short term end point, and no adverse reactions were observed until the last follow up at 27 weeks old (PMA 52-53 weeks) recorded for all babies.
Discussion :
Conclusion : Primary prevention through well-managed screening programme for premature infants was the more effective way to manage the ROP. Intravitreal anti-VEGF treatment could be promising for management of ROP if it was given on the right time and early stadium.
Profile of Unilateral Cataract in Pediatric Patients: A 3 Year Retrospective Study
Authors: Lisana Himmatul Ulya  , Liana Ekowati  
Published: February 2024

Abstract
Introduction & Objectives : Unilateral cataract presents from 19.6% to 55.5% of pediatric cataract in children by many previous reported studies. This condition is treatable, but delayed treatment may cause visual impairment. This study aims to understand characteristic and treatment of unilateral cataract in children.
Methods : The study involved a retrospective review of medical records of patients aged 0-17 years with unilateral cataract who presented to Dr. Kariadi Hospital Semarang from 2019 to 2022. Cases of cataract secondary to causes such as trauma or uveitis were excluded.
Results : Thirty-five patient was included in this study, 51% of whom were male and 49% female. The mean age at presentation is 60.49  48.23 months and mean age of onset is 36.77  45.94 months. The most common presenting complaint was whitish eye (81%) while others presented with blurred vision. All the patients had leukocoria, 28% have microcornea, 3% have persistent pupillary membrane. Half of patient (51%) have strabismus, with exotropia being the most common type (34.17%). Eight patients had congenital rubella syndrome, one patient had cytomegalovirus infection while others did not have any systemic condition related to cataract. Majority of patient (17%) treated with phacoaspiration, primary posterior capsulotomy, anterior vitrectomy and intraocular lens implantation. Intraocular lens was implanted in 71% patient and 54% patients given spectacles.
Conclusion : Unilateral cataract is disease with isolated and sporadic incident. The majority of patients did not have systemic condition related to unilateral cataract. The most common treatment is phacoaspiration, primary posterior capsulotomy, anterior vitrectomy and intraocular lens implantation.
Management of Full-Thickness Lower Eyelid Defect After MOHS Procedure and Mustard Flap
Authors: SRI IRMANDHA KUSUMAWADHANI  , HISAR DANIEL  , YUNIA IRAWATI  
Published: February 2024

Introduction : Large full-thickness eyelid defects are considered a challenging case. This study reports how to manage the reconstruction of eyelid defect in a case with a history of carcinoma cell basal of the eyelid, which is removed with MOHS procedure and mustard flap reconstruction but full-thickness of more than 50% defect of the lower eyelid remains.
Case Illustration : A 67 years old woman was referred from the dermatology and venereology clinic with a history of eyelid cancer operation, 13 days prior. The patient's chief complaint was the left lower eyelid felt pulled down. Examination revealed a left lower eyelid full-thickness defect of more than 50% and ectropion at the lateral side. An 8 mm lagophthalmos without corneal exposure was present. The reconstruction was done with a lips mucosa graft to form posterior lamella, at the medial side anterior lamella was formed by the glabellar flap, and at the lateral side was formed by a skin graft due to lack of the anterior lamella from the mustard flap previously.
Discussion : Eyelid reconstruction aims to provide adequate globe protection. The principle management of reconstruction in full-thickness eyelid defects horizontally of more than 50% can’t be done by an anterior flap (mustard) only because it's unstable and the eyelid can be retracted. The reconstruction must consist of the anterior and posterior lamella which have to be tight to the periosteum.
Conclusion : One step procedure for large defects of the lower eyelid after cancer removal can be done with considering the proper plan of reconstruction technique.
Phacoemulsification in an unable-lying supine patient: why not?
Authors: Damayanti Yulia 
Published: February 2024

Introduction : This case report describes the author's experiences in performing phacoemulsification on two patients with heart diseases causing them unable to lie flat during surgery.
Case Illustration : The first patient, 60 years old woman, with an age-related cataract in her left eye, who's had hypertensive heart disease. The second patient, 73 years old man, with an age-related cataract in his right eye, who's had congestive heart failure and chronic obstructive pulmonary disease. The above conditions have caused them unable to lie flat on the operating table. The surgeon performed both surgeries in a standing position while the patients were lying in a semi-upright position at an angle of 45 degrees (Fowler's position) with legs straight.
Discussion : The presence of systemic diseases has caused the patients to be unable to lie flat. This condition can be predicted during the pre-operative examination from the history of comorbid diseases by asking whether the patients can lie comfortably in a supine position. Several things that should be considered are the preparation of patients, beds, and surgeons' positions. Other things that must be properly arranged are the height of the irrigation bottle and the magnification and the position of the microscope. The surgeon's standing position during surgery requires higher concentration, apart from the possible fatigue due to relying heavily on one leg.
Conclusion : Cardiovascular, pulmonary, neurologic, and orthopedic conditions can affect positioning during the phacoemulsification phase. Those conditions can be quite a challenge for many surgeons in practice. Ophthalmologists must be prepared when they are confronted with such a case.
Imaging Mismatch of Nail in the Eyeball: What’s next?
Authors: Christella Caroline  , Gladys Kusumowidagdo  , Burhana Mawarasti  , Michael Hartono  , Julie Dewi Barliana  , Rio Rhendy  , Yunia Irawati  , Ari Djatikusumo  
Published: February 2024

Introduction : A retained foreign body (FB) can lead to severe complications, the most devastating of which is eye loss. We present a discrepancy of imaging that resulted in a dilemma in the approach management of a mixed global-adnexal FB case.
Case Illustration : A 31-year-old man came to the emergency room with blurry vision for 1.5 hours after a nail hit his right eye (RE). The visual acuity of RE is light perception. Ophthalmological examination revealed a central Y-shaped full-thickness corneal laceration with iris and vitreous prolapse. The lens appeared cloudy, and the posterior segment was difficult to assess. Imaging showed a foreign metal object asa nail in the oculi to intraconal without penetration to the orbital wall. He was planned to undergo FB extraction with corneal laceration repair and aspiration of lens mass irrigation. However, the nail was hard to find intraoperatively because the vitreous and choroid kept coming out. Hence evisceration with DFG was performed. The nail was found more posteriorly and attached to the bone.
Discussion : While primary repair is the standard practice for open globe injury, managing retained intraocular metallic foreign bodies is controversial. Imaging such as CT scans can help determine the location of FB and approach management. In this case, imaging showed the FB was in the iris plane and not penetrating the orbital wall, so primary repair and FB extraction were planned.
Conclusion : The imaging may not always be accurate in determining the exact location of FB, and the surgical approach may need to be adjusted accordingly.
DIFFERENT APPROACHES IN MANAGING LENS-INDUCED ANGLE CLOSURE GLAUCOMA: A SERIAL CASE
Authors: Wardani Sabrina Indri , Rifada R. Maula , Prahasta Andhika , Gustianty Elsa , Umbara Sonie 
Published: February 2024

Introduction : Lens-induced angle-closure glaucoma can be caused by phacomorphic lens and ectopia lentis. Several factors affect the disease progression. Early diagnosis and appropriate management are important.
Case Illustration : Case 1. A 67-year-old woman presented with acute redness and blurred vision in her left eye with visual acuity (VA) of 1/300 and intraocular pressure (IOP) of 60 mmHg. Axial length showed 23.66 mm and anterior chamber depth (ACD) was 1.61mm (Figure1). She was diagnosed with phacomorphic glaucoma. Phacoemulsification combined with trabeculectomy was performed (Figure2&3). Her VA was improved to 0.08 and her IOP was reduced to 19mmHg after surgery. Case2. A 67-year-old man came with painful blurred vision in his right eye. His VA was a perception of light with an IOP of 40 mmHg. He had axial length of 22.7 mm and ACD of 2.07 mm (Figure4). The lens was anteriorly subluxated and showed zonular laxity. Intracapsular cataract extraction combined with trabeculectomy was performed (Figure5&6). His VA was unchanged while his IOP was reduced to 18 mmHg after surgery.
Discussion : Age older than 60 years old, female gender, short axial length (<23.7 mm), shallow ACD, and zonular laxity are factors for progressivity of lens-induced glaucoma. Cataract removal was a definitive treatment along with IOP-lowering medications. The choice of lens extraction technique varies among individuals.
Conclusion : Removal of cataractous lens is a definitive treatment in conjunction with intraocular pressure and inflammatory regulations for managing lens-induced angle-closure glaucoma. Comprehensive clinical assessments in patients are necessary for managing the symptoms and preventing complications.
The effect of topical atropine 0.05% compared to atropine 0.01% for Myopia control in Children : A Meta-analysis
Authors: DEWI INGGRIANA SUKMA , SAVITA SALMA 
Published: February 2024

Introduction & Objectives : Myopia is the most common ocular anomaly manifesting during primary school and progresses until a mean age of 16, but rarely beyond age of 25. Atropine, a nonselective muscarinic antagonist, has been studied widely in recent years as an option for myopia control. To analyse the efficacy of Atropine 0,05% compared with Atropine 0,01 % for myopia control in children aged 4-16 years toward the axial length examination through a meta-analysis.
Methods : A systematic search was performed using Medline and Cochrane database up to December 2022. Review was performed according to the PRISMA Statement. The eligible studies were RCTs which comparing Atropine concentration 0.05% with 0.01%.
Results : From 101 retrieved articles, 5 trials involving total 1035 patients were included. The follow-up period of the studies was 1-2 year. The analysis shows Atropine 0,05% significantly decrease axial length (Mean Difference [MD]: -0.11, 95%CI [-0.15-0.07], p<0.00001, I2= 99 %) comparing to Atropine 0,01%.
Conclusion : In myopia control in children, atropine 0,05 % was more effective to reduce myopia progression in controlling axial length elongation over a period of 1-2 year comparing to atropine 0,01%.
EFFECT OF “SENAM PERMATA-KU” COMPARED WITH WARM COMPRESS ON THE AMPLITUDE OF ACCOMMODATION IN COMPUTER VISION SYNDROME PATIENTS
Authors: Setiawan Teguh , Nugroho Trilaksana , Dharma Andhika Guna , Rahmi Fifin L. , Sadasih Wisnu 
Published: February 2024

Introduction and Objective: The COVID-19 pandemic has virtually made many work activities, resulting in increased use of Visual Display Terminals (VDT) at work and home. Excessive close-range activities due to the use of VDT causes Computer Vision Syndrome (CVS). Various therapies, such as ocular yoga and warm compress, have been created to reduce CVS-related complaints. Diponegoro University developed “Senam PERMATA-KU” as an alternative therapy to reduce complaints related to CVS. This study compares the effect of “Senam PERMATA-KU” and periocular warm compress on the amplitude of accommodation (AA) value in patients with CVS.
Methods: The study subjects were divided into “Senam PERMATA-KU” group (22 people) and periocular warm compress group (20 people) with each treatment for two weeks. CVS score was measured using CVS-Questionnaire and AA using Prince’s rule. Both variables were assessed before and after treatment. Data were collected and analyzed using a statistical computer program.
Result: “Senam PERMATA-KU” group experienced a significant increase in monocular and binocular AA (p<0.001 and p=0.006), while periocular warm compress did not show a significant difference (p=0.982 and p=0.483). The mean delta of monocular and binocular AA between groups differed significantly (p=0.001 and p=0.034). The mean CVS scores in both groups have significant improvement (p<0.001), while the mean delta CVS scores between groups was not significant (p=0.522).
Conclusion: “Senam PERMATA-KU” for two weeks significantly increased monocular and binocular AA, while periocular warm compress showed no significant difference. “Senam PERMATA-KU” and periocular warm compress can significantly reduce CVS score, whereas the difference between the two is insignificant.
THERMAL IMAGING ACCURACY ON CLINICAL ACTIVITY SCORE (CAS) THYROID EYE DISEASE PATIENTS
Authors: MUHAMMAD REZA ARLAS  , Dr. Devi Azri Wahyuni, Sp.M, Sub.Sp NO, MARS  
Published: February 2024

Abstract
Introduction & Objectives : Thyroid Eye Disease (TED) also known as Graves' ophthalmopathy, thyroid-associated orbitopathy, and other terms is an autoimmune inflammatory disorder with the most common extra-thyroid manifestations of Graves' Disease (GD). The disease phase is usually assessed clinically, by assessing the presence or absence of cardinal signs and symptoms of inflammation which are assessed in the form of a clinical activity score (CAS). In addition, the use of Thermal Imaging (IT) as a passive measurement technique that does not require contact with the patient (non-invasive and non- contact) and does not use ionizing radiation or contrast agents is another option. The use of TI in patients with TED still has minimal data and does not have more specific results. This study aims to determine the accuracy of TI and CAS images in TED patients.
Methods : This study design is accuracy test at the Ophthalmology Polyclinic of RSUP Dr. Mohamad Hoesin Palembang in July 2021 until the sample is filled with 24 people. Thermal Imaging (TI) accuracy test was performed to establish active and inactive TED compared to CAS (Clinical Activity Score) in TED patients. Analysis of research results with SPSS version 22.0.
Results : The result shown that the proportion of research subjects who were female was 17 people (70.8%) and male research subjects were 7 people (29.2%). At 7 locations the Thermal Imaging examination was found to have varying sensitivity
Conclusion : Thermal Imaging can be used to help diagnose active and inactive TED.