bluuebunny/crossref_metadata_2025_split huggingface dataset:
Peripheral magnetic stimulation for chronic peripheral neuropathic pain: A systematic review and meta‐analysis
Authors: Dana Elad , Tran Cody , Osokin Evgeny , Westwood Duncan , Moayedi Massieh , Sabhaya Priyancee , Khan James S. 
Published: December 2023

AbstractObjectivesTo provide a systematic review of the literature on the effects of peripheral magnetic stimulation (PMS) in the treatment of chronic peripheral neuropathic pain.MethodsA systematic search of MEDLINE, EMBASE, CENTRAL, CINHAL, Web of Science, and ProQuest was conducted from inception to July 2023 to identify studies of any design published in English language that enrolled adult patients (≥18 years) that received PMS for treatment of a chronic peripheral neuropathic pain disorder (pain > 3 months).ResultsTwenty‐three studies were identified which included 15 randomized controlled trials (RCTs), five case series, two case reports, and one non‐randomized trial. PMS regimens varied across studies and ranged from 5 to 240 min per session over 1 day to 1 year of treatment. Results across included studies were mixed, with some studies suggesting benefits while others showing no significant differences. Of nine placebo‐controlled RCTs, four reported statistically significant findings in favor of PMS use. In the meta‐analysis, PMS significantly reduced pain scores compared to control within 0–1 month of use (mean difference −1.64 on a 0–10 numeric rating scale, 95% confidence interval −2.73 to −0.56, p = 0.003, I2 = 94%, 7 studies [264 participants], very low quality of evidence), but not at the 1–3 months and >3 months of PMS use (very low and low quality of evidence, respectively). Minimal to no adverse effects were reported with PMS use.DiscussionThere is limited and low‐quality evidence to make definitive recommendations on PMS usage, however, the available data is encouraging, especially for short‐term applications of this novel modality. Large high‐quality randomized controlled trials are required to establish definitive efficacy and safety effects of PMS.
Case report: Dorsal root ganglion stimulator lead fracture
Authors: Kochat Suhas , Byers Jacob , Yi Peter K. 
Published: December 2023

AbstractBackgroundOne of the unique advances in neuromodulation for chronic pain has been spinal cord stimulators (SCS) and dorsal root ganglion stimulators (DRG‐S). These devices have aided in conditions such as neuropathic pain, complex regional pain syndromes, failed back surgery, and peripheral neuropathies. With these benefits, however, complications from implantable stimulators have included lead fractures and migration. The authors reviewed a lead migration, kinking, and subsequent fracture event involving a patient with complex regional pain syndrome (CRPS) II, who was treated with a DRG‐S.Case PresentationThe case report follows this patient, from their past medical history to assessment of appropriate qualifications for neuromodulation, to successful surgical placement, to follow‐up care. The authors further monitored assessment of inefficacy of pain relief, and identification of lead migration and kinking through imaging. In the process of removal, due to lead stress, lead fracturing occurred. After lead removal, the leads were fully replaced, and the patient was followed up and experienced improved pain relief.ConclusionThe case report assesses probable mechanisms of lead fracture and considerations for physicians for future assessment and triage of neuromodulation efficacy.
Live two‐way video versus face‐to‐face treatment for depression, anxiety, and obsessive‐compulsive disorder: A 24‐week randomized controlled trial
Authors: Kishimoto Taishiro , Kinoshita Shotaro , Kitazawa Momoko , Hishimoto Akitoyo , Asami Takeshi , Suda Akira , Bun Shogyoku , Kikuchi Toshiaki , Sado Mitsuhiro , Takamiya Akihiro , Mimura Masaru , Sato Yasunori , Takemura Ryo , Nagashima Kengo , Nakamae Takashi , Abe Yoshinari , Kanazawa Tetsufumi , Kawabata Yasuo , Tomita Hiroaki , Abe Koichi , Hongo Seiji , Kimura Hiroshi , Sato Aiko , Kida Hisashi , Sakuma Kei , Funayama Michitaka , Sugiyama Naoya , Hino Kousuke , Amagai Toru , Takamiya Maki , Kodama Hideyuki , Goto Kenichi , Fujiwara Shuichiro , Kaiya Hisanobu , Nagao Kiichiro ,   the J‐PROTECT collaborators
Published: December 2023

AimLive two‐way video, easily accessible from home via smartphones and other devices, is becoming a new way of providing psychiatric treatment. However, lack of evidence for real‐world clinical setting effectiveness hampers its approval by medical insurance in some countries. Here, we conducted the first large‐scale pragmatic, randomized controlled trial to determine the effectiveness of long‐term treatment for multiple psychiatric disorders via two‐way video using smartphones and other devices, which are currently the primary means of telecommunication.MethodsThis randomized controlled trial compared two‐way video versus face‐to‐face treatment for depressive disorder, anxiety disorder, and obsessive‐compulsive disorder in the subacute/maintenance phase during a 24‐week period. Adult patients with the above‐mentioned disorders were allocated to either a two‐way video group (≥50% video sessions) or a face‐to‐face group (100% in‐person sessions) and received standard treatment covered by public medical insurance. The primary outcome was the 36‐Item Short‐Form Health Survey Mental Component Summary (SF‐36 MCS) score. Secondary outcomes included all‐cause discontinuation, working alliance, adverse events, and the severity rating scales for each disorder.ResultsA total of 199 patients participated in this study. After 24 weeks of treatment, two‐way video treatment was found to be noninferior to face‐to‐face treatment regarding SF‐36 MCS score (48.50 vs 46.68, respectively; p < 0.001). There were no significant differences between the groups regarding most secondary end points, including all‐cause discontinuation, treatment efficacy, and satisfaction.ConclusionTwo‐way video treatment using smartphones and other devices, was noninferior to face‐to‐face treatment in real‐world clinical settings. Modern telemedicine, easily accessible from home, can be used as a form of health care.
Athletic competition between the states: The rapid spread of Name, Image, Likeness laws and why it matters for understanding policy diffusion
Authors: Colvin Roshaun , Jansa Joshua M. 
Published: December 2023

AbstractIn the study of the policy diffusion process, scholars have found that states adopt policies to remain competitive with one another over economic resources. But the rapid spread of Name, Image, and Likeness (NIL) policies, which treat college athletes as professionals, is not readily explained by economic competition nor other diffusion mechanisms. The NIL phenomenon points to a new dimension of competition between the states, which is more closely tied to states protecting or enhancing their reputations than it is to directly accruing economic resources. To test if NIL spread as the result of athletic reputation competition, we model the adoption of NIL legislation as a function of internal characteristics (i.e. number, value, and ranking of college football programs) and interstate dynamics (i.e. actions of football, conference, and Power 5 competitors). We test the effect of these measures alongside traditional diffusion indicators, finding that both internal and interstate indicators of athletic competition drive states to adopt and implement NIL. NIL is important to study as it has changed the landscape of amateur sports, as well as our scholarly understanding of policy diffusion in the American federal system, specifically broadening our conceptualization of the competition mechanism and developing customized measures of it.
NnSnRK1‐NnATG1‐mediated autophagic cell death governs flower bud abortion in shaded lotus
Authors: Li Xiehongsheng , Xu Yingchun , Wei Zongyao , Kuang Jiaying , She Mingzhao , Wang Yanjie , Jin Qijiang 
Published: December 2023

SUMMARYMany plants can terminate their flowering process in response to unfavourable environments, but the mechanisms underlying this response are poorly understood. In this study, we observed that the lotus flower buds were susceptible to abortion under shaded conditions. The primary cause of abortion was excessive autophagic cell death (ACD) in flower buds. Blockade of autophagic flux in lotus flower buds consistently resulted in low levels of ACD and improved flowering ability under shaded conditions. Further evidence highlights the importance of the NnSnRK1‐NnATG1 signalling axis in inducing ACD in lotus flower buds and culminating in their timely abortion. Under shaded conditions, elevated levels of NnSnRK1 activated NnATG1, which subsequently led to the formation of numerous autophagosome structures in lotus flower bud cells. Excessive autophagy levels led to the bulk degradation of cellular material, which triggered ACD and the abortion of flower buds. NnSnRK1 does not act directly on NnATG1. Other components, including TOR (target of rapamycin), PI3K (phosphatidylinositol 3‐kinase) and three previously unidentified genes, appeared to be pivotal for the interaction between NnSnRK1 and NnATG1. This study reveals the role of autophagy in regulating the abortion of lotus flower buds, which could improve reproductive success and act as an energy‐efficient measure in plants.
Statistical Approaches for the Reduction of Measurement Errors in Metrology
Authors: Gille Marc , Beaurepaire Pierre , Gayton Nicolas , Dumas Antoine , Yalamas Thierry 
Published: December 2023

Abstract
Metrology is extensively used in the manufacturing industry to determine whether the dimensions of parts are within their tolerance interval. However, measurement errors cannot be avoided. Metrology experts are of course aware of it and they are able to identify the different sources that contribute to making errors. In this paper, the probability density function of the measurement error is considered as a given input. As it is rare to have access to this distribution, there are very few methods in the literature that aim to use this knowledge directly to improve the measurements obtained in metrology. A first method is proposed to correct the effects of the measurement errors on the distribution that characterizes a set of measurements. Then a second method is proposed to estimate the true value that is hidden behind each single measurement, by removing the measurement error statistically. The second method is based on the output knowledge of the first, which is integrated with Bayesian statistics. The relevance of these two methods is shown through two examples applied on simulated data.
Acute myositis secondary to Epstein-Barr virus in the absence of infectious mononucleosis with severe rhabdomyolysis
Authors: Tuchinsky Adam , Montalvo Angela , Lent Dale , Goldman John 
Published: December 2023

SummaryRhabdomyolysis is characterised by muscle breakdown which causes myoglobin light chain release and can result in renal injury. While some of the most common causes of rhabdomyolysis are trauma related, others include toxins, autoimmune processes or viral aetiologies. We present the case of a 20s-year-old man, with no significant medical history, who presented to the emergency department with a 1-week history of weakness, myalgias, nausea, vomiting and subjective fevers. A review of systems and physical exam were otherwise unremarkable, including being negative for sore throat, dysphagia and lymphadenopathy. On presentation, the patient was noted to have dark urine with a creatine kinase value of 452 458 U/L and an elevated creatinine at 7.23 mg/dL. The patient denied any trauma or increased physical activity. His toxin screen and autoimmune workup were negative. The patient’s serological workup was significant for acute Epstein-Barr virus (EBV) infection, without additional viral coinfection or mononucleosis. During his hospitalisation course, the patient was managed with supportive care including haemodialysis. The patient made a full renal recovery and was discharged with scheduled outpatient follow-up. This case highlights the recognition of an acute EBV infection causing rhabdomyolysis in the absence of mononucleosis or concomitant infection.
Efficacy of cola ingestion for oesophageal food bolus impaction: open label, multicentre, randomised controlled trial
Authors: Tiebie E G , Baerends E P , Boeije T , Frankenmolen P G , Lameijer H , van den Berg W , van Stralen K J , Ridderikhof M L , Bredenoord A J 
Published: December 2023

AbstractObjectiveTo determine the efficacy and safety of cola in resolving complete oesophageal food bolus impaction.DesignOpen label, multicentre, randomised controlled trial.SettingEmergency departments of five Dutch hospitals at the secondary and tertiary level, between 22 December 2019 and 16 June 2022.Participants51 adults presenting with complete oesophageal food bolus impaction, defined as a sudden inability to pass saliva after consumption of foods. Patients who ingested meat that contained bones, and patients with an American Society of Anesthesiologists (ASA) physical status classification of IV or higher were excluded.Interventions28 patients in the intervention group were instructed to consume 25 mL cups of cola at intervals up to a maximum total volume of 200 mL. 23 patients in the control group awaited spontaneous passage. In either group, if complete resolution of symptoms did not occur, endoscopic removal was performed following current guidelines: within 6 hours for patients with complete obstruction, and within 24 hours for partial obstruction. In case of complete resolution of symptoms, elective diagnostic endoscopy was required.Main outcome measuresImprovement of oesophageal food bolus obstruction as reported by patients (ie, aggregate of complete and partial passage), and evaluation of complete passage. The secondary outcome was any intervention related adverse event.ResultsCola did not have a meaningful effect on the improvement of food bolus obstruction (17/28 (61%) interventionv14/23 (61%) control; odds ratio 1.00, 95% confidence interval 0.33 to 3.1; relative risk reduction 0.0, 95% confidence interval −0.55 to 0.36; P>0.99). Complete passage was reported more often in the intervention group but this difference was not significant (12/28 (43%) interventionv8/23 (35%) control; odds ratio 1.4 (0.45 to 4.4); relative risk reduction −0.23 (−1.5 to 0.39); P=0.58). No severe adverse events occurred. However, six (21%) patients in the intervention group experienced temporary discomfort after drinking cola.ConclusionsIn this study, cola consumption did not lead to a higher rate of improvement of complete oesophageal food bolus impaction. Given the lack of adverse events in the treatment group and some events of resolution after treatment, cola might be considered as a first line treatment, but should not delay any planning of endoscopic management.Trial registrationNetherlands Trial Register (currently International Clinical Trial Registry Platform) NL8312.
Social determinants of health among people working on informal gold mines in French Guiana: a multicentre cross-sectional survey
Authors: Douine Maylis , Lambert Yann , Plessis Lorraine , Jimeno Irène , Galindo Muriel , Bardon Teddy , Le Tourneau François-Michel , Molinié Perrine , Vié Alexandre , Adenis Antoine , Nacher Mathieu , Figueira da Silva Amanda , Vreden Stephen , Suarez-Mutis Martha Cécilia , Sanna Alice 
Published: December 2023

IntroductionSocial determinants of health, such as living and working conditions, economical and environmental context and access to care, combine to impact the health of individuals and communities. In French Guiana (FG), the persons working in informal artisanal and small-scale gold mining in the rainforest are a particularly vulnerable population which lives in precarious conditions and far from the health system. Previous studies have demonstrated their high morbidity due to infectious diseases. This study aims to describe the social determinants of health in this specific population.MethodsThis international multicentre cross-sectional survey included people working on the informal FG gold mines at the crossing points located at both borders with Suriname and Brazil. After collecting written informed consent, a structured questionnaire was administered.ResultsFrom September to December 2022, 539 gold miners were included. These poorly educated migrants, mainly from Brazil (99.1%) did not have access to drinkable water (95.4%), lived in close contact with wild fauna by hunting, eating bushmeat or being bitten and were exposed to mercury by inhalation (58.8%) or ingestion (80.5%). They report frequent accidents (13.5%) and chronic treatment interruptions (26.6% of the 11.9% reporting chronic treatment). Half of them considered themselves in good health (56.4%).ConclusionThis study shows a singular combination of adverse exposures of gold miners working in FG such as zoonoses, heavy metal poisoning, aggression of wild fauna. For ethical as well as public health reasons, actions towards health equity must be considered at different levels: individual, community, environmental, systemic and global level. As end users of minerals, we must assume our responsibilities for the well-being of the extractors by including health in political decisions to engage together in global health.Trial registration numberNCT05540470.
Lifting all boats: strategies to promote equitable bidirectional research training opportunities to enhance global health reciprocal innovation
Authors: Muddu Martin , Jaffari Adiya , Brant Luisa C C , Kiplagat Jepchirchir , Okello Emmy , Masyuko Sarah , Su Yanfang , Longenecker Chris Todd 
Published: December 2023

Inequities in global health research are well documented. For example, training opportunities for US investigators to conduct research in low-income and middle-income countries (LMIC) have exceeded opportunities for LMIC investigators to train and conduct research in high-income countries. Reciprocal innovation addresses these inequities through collaborative research across diverse global settings.The Fogarty International Center of the US National Institutes of Health (NIH) promotes research capacity building in LMICs. Fogarty K-grants for mentored career development in global health are available for both US and LMIC investigators, whereas the D43 is the standard grant to support institutional training programmes in LMIC. Other NIH institutes fund T32 training grants to support biomedical research training in the USA, but very few have any global health component. Most global health training partnerships have historically focused on research conducted solely in LMIC, with few examples of bidirectional training partnerships. Opportunities may exist to promote global health reciprocal innovation (GHRI) research by twinning K-awardees in the USA with those from LMIC or by intentionally creating partnerships between T32 and D43 training programmes.To sustain independent careers in GHRI research, trainees must be supported through the path to independence known as the K (mentored grantee)-to-R (independent grantee) transition. Opportunities to support this transition include comentorship, research training at both LMIC and US institutions and protected time and resources for research. Other opportunities for sustainability include postdoctoral training before and after the K-award period, absorption of trained researchers into home institutions, South-South training initiatives and innovations to mitigate brain drain.
Authorship inequalities in global health research: the IeDEA Southern Africa collaboration
Authors: Skrivankova Veronika W , Hossmann Stefanie , Cornell Morna , Ballif Marie , Dupont Carole , Huwa Jacqueline , Seintaridis Konstantinos , Kalua Thokozani , Wandeler Gilles , Kassanjee Reshma , Haas Andreas D , Technau Karl-Gunter , Fenner Lukas , Low Nicola , Davies Mary-Ann , Egger Matthias 
Published: December 2023

BackgroundThe International epidemiology Databases to Evaluate AIDS conducts research in several regions, including in Southern Africa. We assessed authorship inequalities for the Southern African region, which is led by South African and Swiss investigators.MethodsWe analysed authorships of publications from 2007 to 2020 by gender, country income group, time and citation impact. We used 2020 World Bank categories to define income groups and the relative citation ratio (RCR) to assess citation impact. Authorship parasitism was defined as articles without authors from the countries where the study was conducted. A regression model examined the probability of different authorship positions.ResultsWe included 313 articles. Of the 1064 contributing authors, 547 (51.4%) were women, and 223 (21.0%) were from 32 low-income/lower middle-income countries (LLMICs), 269 (25.3%) were from 13 upper middle-income countries and 572 (53.8%) were from 25 high-income countries (HICs). Most articles (150/157, 95.5%) reporting data from Southern Africa included authors from all participating countries. Women were more likely to be the first author than men (OR 1.74; 95% CI 1.06 to 2.83) but less likely to be last authors (OR 0.63; 95% CI 0.40 to 0.99). Compared with HIC, LLMIC authors were less likely to publish as first (OR 0.21; 95% CI 0.11 to 0.41) or last author (OR 0.20; 95% CI 0.09 to 0.42). The proportion of women and LLMIC first and last authors increased over time. The RCR tended to be higher, indicating greater impact, if first or last authors were from HIC (p=0.06).ConclusionsThis analysis of a global health collaboration co-led by South African and Swiss investigators showed little evidence of authorship parasitism. There were stark inequalities in authorship position, with women occupying more first and men more last author positions and researchers from LLMIC being ‘stuck in the middle’ on the byline. Global health research collaborations should monitor, analyse and address authorship inequalities.
Creation of an institutional preoperative checklist to support clinical risk assessment in patients with ulcerative colitis (UC) considering ileoanal pouch surgery
Authors: Alves Martins Bruno Augusto , Shamsiddinova Amira , Alquaimi Manal Mubarak , Worley Guy , Tozer Phil , Sahnan Kapil , Perry-Woodford Zarah , Hart Ailsa , Arebi Naila , Matharoo Manmeet , Warusavitarne Janindra , Faiz Omar 
Published: December 2023

BackgroundTotal proctocolectomy with ileal pouch–anal anastomosis (IPAA) is the most established restorative operative approach for patients with ulcerative colitis. It has associated morbidity and the potential for major repercussions on quality of life. As such, patient selection is crucial to its success. The main aim of this paper is to present an institutional preoperative checklist to support clinical risk assessment and patient selection in those considering IPAA.MethodsA literature review was performed to identify the risk factors associated with surgical complications, decreased functional outcomes/quality of life, and pouch failure after IPAA. Based on this, a preliminary checklist was devised and modified through an iterative process. This was then evaluated by a consensus group comprising the pouch multidisciplinary team (MDT) core members.ResultsThe final preoperative checklist includes assessment for risk factors such as gender, advanced age, obesity, comorbidities, sphincteric impairment, Crohn’s disease and pelvic radiation therapy. In addition, essential steps in the decision-making process, such as pouch nurse counselling and discussion regarding surgical alternatives, are also included. The last step of the checklist is discussion at a dedicated pouch-MDT.DiscussionA preoperative checklist may support clinicians with the selection of patients that are suitable for pouch surgery. It also serves as a useful tool to inform the discussion of cases at the MDT meeting.