bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advances in Additive Manufacturing Techniques for Electrochemical Energy Storage
Authors: De Adrija , Ramasubramian Brindha , Ramakrishna Seeram , Chellappan Vijila 
Published: December 2023

AbstractThe increasing adoption of additive manufacturing (AM), also known as 3D printing, is revolutionizing the production of wearable electronics and energy storage devices (ESD) such as batteries, supercapacitors, and fuel cells. This surge can be attributed to its outstanding process versatility, precise control over geometrical aspects, and potential to reduce costs and material waste. In this comprehensive review, major AM processes like inkjet printing, direct ink writing, fused deposition modeling, and selective laser sintering/melting along with possible configurations and architectures, are elaborately discussed for each bespoke ESD. The application of 3D‐printed energy storage devices in wearable electronics, Internet of Things (IoT)‐based devices, and electric vehicles are also mentioned in the review. The role of AM in facilitating the production of solid‐state batteries has also revolutionized the electric vehicle (EV) industry. Recent progress in the field of AM of energy systems with solid electrolytes and potential future directions such as 4D printing to incorporate stimuli‐responsive behavior in 3D‐printed materials, biomimetic design optimization, and additive manufacturing of ESD in a micro‐gravity environment have also been highlighted. Extensive research and continuous progress in this field are expected to enhance the longetivity, industrial scalability, and electrochemical performance of 3D‐printed energy storage devices in future.
Injectable Hydrogel Incorporated with Iron‐Doped Carbon Dots Exhibiting Peroxidase‐Like Activity for Antibacterial Therapy and Wound Healing
Authors: Li Tianliang , Lin Lixing , Wang Dong , Fang Haowen , Zhang Zhiwei , Wang Yitong , Chen Yingying , Feng Lingyan 
Published: December 2023

AbstractThe increasing bacterial resistance highlights the necessity of developing superior antibacterial materials. Metal‐doped carbon dots (CDs), a crucial branch of carbon‐based nanozymes, exhibit efficient antibacterial properties using the reactive oxygen species (ROS) effect. In this study, iron‐doped carbon dots (Fe‐CDs) are synthesized with high peroxidase‐like (POD‐like) activity using natural hemin as a precursor for the first time. The formation of Fe‐CDs remarkably improves the water solubility of hemin showing excellent biocompatibility. Additionally, iron is doped from hemin to the CDs surface, reducing the risk of trial‐and‐error associated with adding an external iron source. The Fe‐CDs‐hydrogel system is constructed via the incorporation of Fe‐CDs into a dual‐crosslinked injectable hydrogel, taking advantage of the synergistic effects. The system enhances the mechanical properties of hydrogel and serves as an excellent carrier for Fe‐CDs. It exhibits effective antibacterial activity at low hydrogen peroxide (H2O2) concentrations (10−4 m) via the activation of Fenton‐like reaction‐triggered POD‐like catalytic activity and the electrostatic interactions. The system further demonstrates excellent healing efficacy in a bacteria‐infected wound model by reducing inflammation levels and accelerating the regeneration of tissues. This study provides a novel approach for applying nanozymes in antibacterial therapy and wound healing.
Youth sociopolitical development: A conceptual framework by racial and gender minoritized youth organizers
Authors: Malorni Angie , Dolan Shae , Hong Andrew , Joseph Naima , Mohamed Khalid , Moore Liana , Phan Linda , Skoglund Ireland , Too Iris , Wittman Sidonie 
Published: December 2023

AbstractYouth sociopolitical development (SPD) is a powerful protective and promotive factor for marginalized adolescents' social, emotional, physical, and academic well‐being. Despite having unique insight and experiential knowledge about SPD processes, youth have been excluded from conceptual framework and model development. As part of a Youth Participatory Action Research project, 11 adolescents (ages 14–19) and one adult ask “How do adolescent community organizers with varying social and political experiences conceptualize youth SPD?” We used a multiple case study design, with a grounded theory analytic approach. The YPAR collective identified four interrelated, experiential domains of youth SPD: thinking, feeling, doing and relating. Within each domain, we identified and defined key constructs and practices. The YPAR collective's qualitative inquiry resulted in more nuance for existing frameworks of critical consciousness and critical action, and the collective pushes the SPD field to better integrate social and emotional aspects of SPD practice. They offer a conceptual framework that is rooted in their experiential, sensory, learned, and social knowledge, from a multiple‐marginalized positionality. These insights enrich the fields of SPD research and practice.
Jahn–Teller Distortions Induced by in situ Li Migration in λ‐MnO2 for Boosting Electrocatalytic Nitrogen Fixation
Authors: Gao Zijian , Zhao Zhi‐hao , Wang Haifan , Bai Yiling , Zhang Xuehua , Zhang Zeyu , Mei Hui , Yuan Menglei , Zhang Guangjin 
Published: December 2023

AbstractLithium‐mediated electrochemical nitrogen reduction reaction (Li‐NRR) completely eschews the competitive hydrogen evolution reaction (HER) occurred in aqueous system, whereas the continuous deposition of lithium readily blocks the active sites and further reduces the reaction kinetics. Herein, we propose an innovative in situ Li migration strategy to realize that Li substitutes Mn sites in λ‐MnO2 instead of evolving into the dead Li. Comprehensive characterizations corroborate that the intercalation of Li+ at high voltage breaks the structural integrity of MnO6 octahedron and further triggers unique Jahn–Teller distortions, which promotes the spin state regulation of Mn sites to generate the ameliorative eg orbital configuration and accelerates N≡N bond cleavage via eg‐σ and eg‐π* interaction. To this end, the resulted cationic disordered LiMnO4 delivers the recorded highest NH3 yield rate of 220 μg h−1 cm−2 and a Faradaic efficiency (FE) 83.80 % in organic electrolyte.
Sterically Controlled Synthesis of Amine‐Free CsPbBr3 Nanoplatelets for Stable, Pure‐Blue Light Emission
Authors: Chen Dezhang , Wang Tyler , Kei Ko Pui , Shi Jinquan , Liu Mengxia , Halpert Jonathan E. 
Published: December 2023

AbstractMetal halide perovskite nanoplatelets (NPLs) have demonstrated excellent optical properties for light‐emitting applications and achieved tunable blue luminescence through thickness control. However, their translation into electronic devices has lagged behind due to poor colloidal and film stability. The main reason for this is the deprotonation of their surface‐capped ammonium passivating ligands, resulting in NPL aggregation. Here we report the first facile synthesis of amine‐free pure‐blue CsPbBr3 NPLs with outstanding thermal and light stability. This is achieved by utilizing an amine‐free phosphine oxide route with a surface capping molecule exhibiting large steric hindrance to prevent NPL aggregation. Two‐dimensional nuclear magnetic resonance (2D NMR) spectroscopy suggests slower ligand exchange in amine‐free NPLs compared to the conventional NPLs, which can be attributed to the strong binding strength of the designated ligand. Consequently, the amine‐free NPLs exhibited superior stability against radiation, heat and moisture. We further demonstrate the importance of acid‐base equilibrium in this amine‐free synthesis route. Through solvent neutralization and passivation with various alkali carbonates, the resulting NPLs attained near‐unity photoluminescence quantum yield (PLQY) and pure blue emission.
Development of a simultaneous quantification method of imatinib and sunitinib and their main metabolites and its application in patients with gastrointestinal stromal tumor
Authors: Chen Hefen , Lyu Jianbo , Gong Zhujun , Han Yong , Tao Kaixiong , Zhou Hong 
Published: December 2023

AbstractCorrelations between plasma concentrations of imatinib and sunitinib with efficacy and toxicity have been established. It is crucial to develop a sensitive and precise method for determining the plasma concentrations of imatinib and sunitinib, along with their active metabolites, to facilitate therapeutic drug monitoring and individualized therapy. Plasma samples were separated on an Agilent ZORBAX SB‐C18 chromatographic column using gradient elution. Quantification was performed using a mass spectrometer equipped with electrospray ionization in multiple reaction monitoring. The analysis time was 18 min per run, with all analytes and internal standards eluting within 8 min. The calibration range was 25–4000 ng/mL for imatinib, 5–800 ng/mL for N‐desmethyl imatinib (CGP74588), and 2.5–400 ng/mL for sunitinib and N‐desethyl sunitinib (SU12662). Intra‐ and inter‐assay precision were both below 15%, and accuracy ranged between 90.0% and 101.9%. The method was successfully applied to determine blood samples from 120 patients with gastrointestinal stromal tumors who received imatinib (n = 115) and sunitinib (n = 5). It has been validated as linear, accurate, precise, and robust, making it suitable for therapeutic drug monitoring of imatinib and sunitinib in routine clinical practice.
Atypical hemolytic uremic syndrome in a child: A rare case report
Authors: Kunwor Bishal , Sharma Bishal , Chhetri Suchit Thapa , Joshi Prerana , Pradhan Dipendra 
Published: December 2023

Key Clinical MessageAtypical hemolytic uremic syndrome, a rare thrombotic microangiopathy, necessitates early diagnosis and comprehensive care due to its potential severity, emphasizing the importance of a multidisciplinary approach to improve outcomes.
Trauma and chorioretinal shockwave injury from intra‐orbital foreign body
Authors: Motamed Shariati Mehrdad , Sahraei Naser , Sadeghi Kakhki Mahshid 
Published: December 2023

Key Clinical MessageHigh‐velocity projectile trauma could lead to intra‐orbital foreign body and concomitant chorioretinal shockwave injury in the absence of open‐globe injury. Management depends on the types, size, and location of foreign bodies.
Spontaneous resolution of proximal humerus sessile osteochondroma: A report of case and literature review
Authors: De Siqueira André Luis , Abd‐Elmaged Hozifa Mohammed Ali , Salih Dafaalla , Mustafa Mustafa Elghazali Abuelgassim E. 
Published: December 2023

Key Clinical MessageIn managing a child with a solitary osteochondroma, the most advisable course of action involves vigilant observation and regular follow‐up, given the potential for spontaneous resolution.AbstractThe most frequent benign cartilage tumors in children are osteochondromas, which develop when the growth plate herniates during bone development. Treatment depends on the symptoms, with asymptomatic cases requiring monitoring and symptomatic patients requiring surgical intervention. Rarely, an asymptomatic osteochondroma may spontaneously disappear. We report the case of a 3‐year‐old male who presented with left arm swelling and pain due to trauma while playing football. X‐rays revealed a proximal humerus posterolateral sessile osteochondroma. After 6 months of observation, the boy tolerated activity and had no pain. Five years later, the osteochondroma was resolved spontaneously both clinically and radiologically. Our study suggests that annual observation of child patients with osteochondroma is more effective than surgical intervention due to the possibility of spontaneous resolution.
Eccrine spiradenoma on the anterior forearm in a pediatric patient: A rare case report
Authors: Habib Zeina M. , Al‐janabi Moatasem Hussein , Ahmad Azhar Sayed , Baddour Roula , Issa Rana 
Published: December 2023

Key Clinical MessageSpiradenoma is a rare benign adnexal tumor arising from eccrine sweat glands. It presents as a painful bluish nodular lesion which occurs rarely over the arms. This case report adds to a case where a recurrent spiradenoma occurred over the arm. The majority of reported cases involve young adults, making our pediatric case particularly unusual. Early diagnosis through excisional biopsy is crucial for optimal management and prevention of recurrence or malignant transformation. Eccrine spiradenoma is an uncommon tumor that should be kept in mind in case of a patient with a painful nodule. More genetic studies are needed for the best understanding of this rare tumor entity.
Conservative management of an advanced external cervical resorption with internal approach using bio‐ceramic materials: A case report
Authors: Ghabraei Sholeh , Bolhari Behnam , Hashemi Nasim , Gharehchahi Hamidreza 
Published: December 2023

Key clinical messageA successful management of an advanced external cervical resorption using a conservative approach with CBCT, dental operating microscope, and a new bio‐ceramic material.AbstractExternal cervical resorption (ECR) is a pathologic condition that is initiated on the external aspect of the root, below the epithelial attachment in the cervical position. This article will report a case of external cervical resorption (ESR) in an advanced stage, which was asymptomatic and was incidentally detected in a follow‐up radiograph after the end of orthodontic treatment. Cone‐beam computed tomography (CBCT) was prescribed to accurately diagnose the resorptive lesion and differentiate it from internal root resorption (IRR), and the final diagnosis was Heithersay's class IV ECR. Considering the health of the periodontium and the absence of attachment loss, it was decided to use a conservative internal approach to the management of this case. After the treatment, the patient was asymptomatic and the radiographic examinations showed no signs of peri‐radicular pathology during the follow‐up period. With the correct case selection and the availability of the appropriate materials and equipment such as a dental operating microscope (DOM) and bio‐ceramic materials, the internal approach can be a successful and minimally invasive treatment, even for the management of advanced ECR cases.
Primary hepatic functional neuroendocrine tumor in an elderly female: Case report
Authors: Kushwaha Naveen Kumar , Jaiswal Pradeep , Gupta Prashant , Mishra Niharika , Kulkarni Shrirang Vasant 
Published: December 2023

Key Clinical MessagePrimary hepatic neuroendocrine tumor, an exceptionally rare subtype, poses a diagnostic challenge. Oncological resections should be considered, even in elderly patients after following protocolized pre‐operative optimizations.AbstractNeuroendocrine tumors (NETs) are rare tumors that primarily develop in the gastrointestinal and respiratory tracts. While the liver is commonly affected by NET metastases, primary hepatic neuroendocrine tumors (PHNETs) are an exceptionally rare subtype. The characteristic slow growth and nonfunctional nature of PHNETs pose challenges in their diagnosis. Furthermore, PHNETs often exhibit a lack of unique radiological characteristics that differentiate them from other liver tumors, leading to frequent misdiagnosis as hepatocellular carcinoma. We performed left hepatectomy for PHNET in an elderly lady with prolonged stormy postoperative course. This case report of a PHNET highlights the importance of histopathology and immunohistochemistry in the diagnosis and emphasizes that oncological resection, if feasible, is the preferred treatment even in the elderly population.
The effects of shear deformation and rotary inertia on the electrical analogs of beams and plates for multimodal piezoelectric damping
Authors: Luo Alan , Lossouarn Boris , Erturk Alper 
Published: December 2023

AbstractAnalogous electrical networks were previously derived from the Euler–Bernoulli and Kirchhoff–Love theories to represent beams and plates, respectively, for use in multimodal structural vibration damping. However, these networks do not account for shear deformations or rotary inertia, which can result in suboptimal vibration damping performance when used on moderately thick beams and plates. In this paper, we investigate the incorporation of shear deformation and rotary inertia using Timoshenko–Ehrenfest beam theory and Mindlin–Reissner plate theory to develop improved electrical networks that can more accurately represent thick beams and plates. Our findings suggest that the inclusion of shear deformation and rotary inertia can significantly improve the frequency coherence of the electrical networks and multimodal vibration damping for thicker structures. The electrical analogs presented here are of use for various applications, especially to conveniently design complex circuit topologies in fields spanning from vibration attenuation to energy harvesting.
Synthesis of Cryptophanes: Recent Advances
Authors: Kancherla Sindhu , Hansen Jørn H. 
Published: December 2023

AbstractThis review covers the latest developments in the synthesis of cryptophane host molecules since the publication of the last extensive review by Brotin and Dutasta in 2009. The literature has been categorized according to the synthetic method for generating the cryptophane core and we also emphasize emerging late‐stage functionalization approaches. The synthetic strategies towards cryptophanes can be broadly categorized into the well‐established direct‐ (two‐step), template‐ and coupling (or capping) methods. The examples covered in this review mainly highlight template‐based synthesis, coupling approaches and late‐stage functionalization.
Preferential flow in the shallow vadose zone: Effect of rainfall intensity, soil moisture, connectivity, and agricultural management
Authors: Williams Mark R. , Ford William I. , Mumbi Rose C. K. 
Published: December 2023

AbstractPreferential flow is ubiquitous in soils, and it affects water infiltration, runoff, and contaminant transport. Undisturbed soil lysimeters (n = 10; 900 cm2) were collected from an agricultural field to quantify the effect of climate, soil moisture, connectivity, and agricultural practices on water transport through the shallow vadose zone. A series of 10 rainfall simulations was conducted on each lysimeter (n = 100 events) and data were analysed within a framework of five case studies where we assessed the impact of rainfall intensity (n = 30 events), soil moisture (n = 28), and tillage (n = 21). Three lysimeters that had near‐zero flow initially were modified to investigate dynamics of direct surface connectivity through an artificial macropore in which we assessed the impacts of soil moisture (n = 12) and subsequent disruption via tillage (n = 9). Stable water isotopes were used to separate leachate into event (Qe) and pre‐event water (Qpe). Results showed that event water transport in leachate was not affected by rainfall intensity (Qe/Q = 49% ± 21% to 50% ± 24%); however, event water decreased from 65% ± 5% to 23% ± 28% with increasing soil moisture. Lysimeters with artificial macropores resulted in leachate that was nearly all event water (85% ± 12% to 92% ± 4%) irrespective of soil moisture. Tillage decreased event water transport for both lysimeters with and without an artificial macropore by ~30%. Findings show how varying initial and boundary conditions produce a continuum of preferential flow. Water and tracer flux data collected in the current study are therefore essential for predicting conditions with high relevance of preferential flow and contaminant transport when assessing or modelling long‐term hydrographs where these conditions are only met during a small proportion of the flow time.
Extracellular vesicles from organoid‐derived human retinal progenitor cells prevent lipid overload‐induced retinal pigment epithelium injury by regulating fatty acid metabolism
Authors: Gao Hui , Zeng Yuxiao , Huang Xiaona , A Luodan , Liang Qingle , Xie Jing , Lin Xi , Gong Jing , Fan Xiaotang , Zou Ting , Xu Haiwei 
Published: December 2023

AbstractRetinal degeneration (RD), a group of diseases leading to irreversible vision loss, is characterised by retinal pigment epithelium (RPE) or retinal neuron damage and loss. With fewer risks of immune rejection and tumorigenesis, stem cell‐secreted extracellular vesicles (EVs) offer a new cell‐free therapeutic paradigm for RD, which remains to be investigated. Human retinal organoid‐derived retinal progenitor cells (hERO‐RPCs) are an easily accessible and advanced cell source for RD treatment. However, hERO‐RPCs‐derived EVs require further characterisation. Here, we compared the characteristics of EVs from hERO‐RPCs (hRPC‐EVs) with those of human embryonic stem cell (hESC)‐derived EVs (hESC‐EVs) as controls. Based on in‐depth proteomic analysis, we revealed remarkable differences between hRPC‐EVs and hESC‐EVs. A comparison between EVs and their respective cells of origin demonstrated that the protein loading of hRPC‐EVs was more selective than that of hESC‐EVs. In particular, hESC‐EVs were enriched with proteins related to angiogenesis and cell cycle, whereas hRPC‐EVs were enriched with proteins associated with immune modulation and retinal development. More importantly, compared with that of hESC‐EVs, hRPC‐EVs exhibited a lower correlation with cell proliferation and a unique capacity to regulate lipid metabolism. It was further confirmed that hRPC‐EVs potentially eliminated lipid deposits, inhibited lipotoxicity and oxidative stress, and enhanced phagocytosis and survival of oleic acid‐treated ARPE‐19 cells. Mechanistically, hRPC‐EVs are integrated into the mitochondrial network of oleic acid‐treated ARPE‐19 cells, and increased the level of mitochondrial fatty acid β‐oxidation‐related proteins. Thus, organoid‐derived hRPC‐EVs represent a promising source of cell‐free therapy for RD, especially for blinding diseases related to abnormal lipid metabolism in RPE cells.