bluuebunny/crossref_metadata_2025_split huggingface dataset:
Panic at the ISCO: Time-varying Double-peaked Broad Lines from Evolving Accretion Disks Are Common among Optically Variable AGNs
Authors: Ward Charlotte , Gezari Suvi , Nugent Peter , Kerr Matthew , Eracleous Michael , Frederick Sara , Hammerstein Erica , Graham Matthew J. , van Velzen Sjoert , Kasliwal Mansi M. , Laher Russ R. , Masci Frank J. , Purdum Josiah , Racine Benjamin , Smith Roger 
Published: January 2024

Abstract
About 3%–10% of Type I active galactic nuclei (AGNs) have double-peaked broad Balmer lines in their optical spectra originating from the motion of gas in their accretion disk. Double-peaked profiles arise not only in AGNs, but occasionally appear during optical flares from tidal disruption events and changing-state AGNs. In this paper, we identify 250 double-peaked emitters (DPEs) among a parent sample of optically variable broad-line AGNs in the Zwicky Transient Facility (ZTF) survey, corresponding to a DPE fraction of 19%. We model spectra of the broad Hα emission-line regions and provide a catalog of the fitted accretion disk properties for the 250 DPEs. Analysis of power spectra derived from the 5 yr ZTF light curves finds that DPE light curves have similar amplitudes and power-law indices to other broad-line AGNs. Follow-up spectroscopy of 12 DPEs reveals that ∼50% display significant changes in the relative strengths of their red and blue peaks over long 10–20 yr timescales, indicating that broad-line profile changes arising from spiral arm or hotspot rotation are common among optically variable DPEs. Analysis of the accretion disk parameters derived from spectroscopic modeling provides evidence that DPEs are not in a special accretion state, but are simply normal broad-line AGNs viewed under the right conditions for the accretion disk to be easily visible. We include inspiraling supermassive black hole binary candidate SDSSJ1430+2303 in our analysis, and discuss how its photometric and spectroscopic variability is consistent with the disk-emitting AGN population in the ZTF survey.
The therapeutic value of thiazole and thiazolidine derivatives in Alzheimer's disease: a systematic literature review
Authors: Abdollahi Zahra , Nejabat Mojgan , Abnous Khalil , Hadizadeh Farzin 
Published: January 2024

Background and purpose:
Alzheimer's disease (AD) is a common neurodegenerative disease and the fifth leading cause of death among the elderly. The development of drugs for AD treatment is based on inhibiting cholinesterase (ChE) activity and inhibiting amyloid-beta peptide and tau protein aggregations. Many in vitro findings have demonstrated that thiazole-and thiazolidine-based compounds have a good inhibitory effect on ChE and other elements involved in the AD pathogenicity cascade.

Experimental approach:
In the present review, we collected available documents to verify whether these synthetic compounds can be a step forward in developing new medications for AD. A systematic literature search was performed in major electronic databases in April 2021. Twenty-eight relevant in vitro and in vivo studies were found and used for data extraction.

Findings/Results:
Findings demonstrated that thiazole-and thiazolidine-based compounds could ameliorate AD's pathologic condition by affecting various targets, including inhibition of ChE activity, amyloid-beta, and tau aggregation in addition to cyclin-dependent kinase 5/p25, beta-secretase-1, cyclooxygenase, and glycogen synthase kinase-3β.

Conclusion and implications:
Due to multitarget effects at micromolar concentration, this review demonstrated that these synthetic compounds could be considered promising candidates for developing anti-Alzheimer drugs.
PI3K/AKT and STAT3 pathways mediate the neuroprotective effect of dasatinib from acute cerebral injury in endotoxemic mice
Authors: Mohammad Ammar Rasoul , Hassan Ekhlas Sabah , Majeed Sahar Abdulrudha 
Published: January 2024

Background and purpose:
Sepsis induces brain dysfunction and there is still a requirement for an unemployed viable restorative approach. This study aimed to investigate the role of dasatinib in the modulation of proinflammatory mediators, attenuating neuroinflammatory response, and it's signaling pathway during endotoxemia.

Experimental approach:
Twenty-four adult male Swiss-albino mice were randomized into four groups: sham (undergo laparotomy without cecal ligation and puncture, sepsis (laparotomy with cecal ligation and puncture), vehicle-dimethyl sulfoxide, dasatinib (20 mg/kg/day) intraperitoneally. Brain tissue used for assessment of interleukin (IL)-6, IL-1β, tumor necrosis factor-alpha (TNF-α), IL-10, Toll-like receptor 4 (TLR4), protein kinase B (AKT), phosphoinositide 3-kinases (PI3K), signal transducer and activator of transcription 3 (STAT3), and histopathological examination.

Findings/Results:
Brain tissue levels of TNF-α, IL-6, and IL1 β were higher in the sepsis group than in the sham and vehicle groups. The dasatinib group had considerably lower tissue levels of these markers and significantly higher tissue values of IL-10 than the sepsis and vehicle groups. The sham group had much lower tissue values of TLR4, AKT, STAT3, and PI3k than in sepsis and vehicle groups. Furthermore, tissue levels of these markers in the dasatinib group were considerably lower than those in the sepsis and vehicle groups. Histopathology demonstrated that dasatinib might considerably reduce brain damage and the intensity of neuroinflammation when compared to sepsis and vehicle groups that showed extensive brain inflammation and damage.

Conclusion and implication:
Dasatinib attenuated endotoxemia-induced acute brain damage in mice via modulating effects on TLR4, PI3K, AKT, and STAT3 downstream signaling pathways.
A comparative study to find the effectiveness of Iyengar Yoga versus Pilates on the anterior pelvic tilt of young females with mechanical low back pain
Authors: Dabhi Palak Suresh 
Published: January 2024

Abstract:

CONTEXT:
Pelvic tilt is one of the root causes behind low back pain (LBP). There are many causes behind LBP and anterior pelvic tilt is one of the leading causes which results in LBP, especially in young females. Interventions activating the core musculature can aid in decreasing the tilting, thereby alleviating the LBP. Iyengar Yoga and Pilates have been proved to be effective in the activation of core musculature in many researches. But no research has been done to prove the effect of both interventions on pelvic tilt, which in turn helps to alleviate LBP.

AIMS:
The aim of this study was to compare the effect of Iyengar Yoga versus Pilates on the anterior pelvic tilt of females with LBP.

SETTINGS AND DESIGN:
college, PG, randomized controlled trial.

SUBJECTS AND METHODS
Questionnaire, digital inclinometer, and clamps. Forty LBP subjects were selected based on inclusion criteria and randomly divided into two groups. Group A (n = 20) Iyengar Yoga and Group B (n = 20) Pilates. Protocol lasted for 45–60 min 3 days/week for 4 weeks. Angulation of tilt (using digital inclinometer, inclinometer was placed on the clamps) and Modified Oswestry LBP Disability Questionnaire-outcome measures.

STATISTICAL ANALYSIS:
SPSS version 2.0 (software used for statistical analysis). Paired, unpaired t-test-outcome 1 and Wilcoxon, Mann–Whitney U-test-outcome 2.

RESULTS:
Pre-and posttest difference for outcome 1 in Group A was 1.34 ± 0.23 and for Group B was 1.55 ± 0.2. For outcome 2, prepost difference in Group A was 3 ± 0.33, Group B was 3.8 ± 0.49.

CONCLUSIONS:
The study concluded that there is no significant difference between both groups on anterior pelvic tilt.
Stabilizers of irreducible components of affine Deligne–Lusztig varieties
Authors: He Xuhua , Zhou Rong , Zhu Yihang 
Published: January 2024

We study the

J_{b}(F)

-action on the set of top-dimensional irreducible components of affine Deligne–Lusztig varieties in the affine Grassmannian. We show that the stabilizer of any such component is a parahoric subgroup of

J_{b}(F)

of maximal volume, verifying a conjecture of X. Zhu. As an application, we give a description of the set of top-dimensional irreducible components in the basic locus of Shimura varieties.
Improving the Quality and Use of Malaria Surveillance Data: Results from Evaluating an Integrated Malaria Information Storage System at the Health Facility Level in Selected Districts in Mozambique
Authors: Stratil Ann-Sophie , Canana Neide , Rodrigues Maria , Armando Sarmento , Gomane Sergio , Zandamela Edson , Baker Kevin , Roca-Feltrer Arantxa , Candrinho Baltazar 
Published: January 2024

ABSTRACT.
Mozambique addressed critical malaria surveillance system challenges by rolling out an integrated malaria information storage system (iMISS) at the district level in February 2021. The iMISS integrates malaria data from existing systems across thematic program areas to improve data availability and use. In seven districts, the platform was extended to health facilities (HFs), allowing HFs to access iMISS and use tablets to submit monthly malaria reports to a central database, eliminating the need for paper-based reporting to districts. A structured evaluation of the iMISS rollout to HFs was carried out in February–July 2021. The four evaluation areas were data quality (reporting rate, timeliness, and fidelity) of monthly malaria reports electronically submitted to the iMISS, adoption of the iMISS for data-informed decision-making, system maintenance, and acceptability of the iMISS among target users. All 94 HFs in the seven targeted districts were assessed. Over the 6-month period, 86.1% of reported cases on the iMISS were consistent with cases recorded in paper-based reports, allowing for up to 10% discrepancy. In addition, 69.0% of expected monthly district meetings were held, and information from iMISS was discussed during 58.6% of these meetings. Maintenance issues, mostly related to tablet access and internet connectivity, were experienced by 74.5% of HFs; 33.7% of issues were resolved within 1 month. The iMISS and electronic submission of malaria reports were well accepted by HF- and district-level users. Continued political commitment and timely execution of issue management workflows are crucial to ensure trust in the new platform and facilitate higher levels of data use.
The long-term results of using 3-patch technique for supravalvular aortic stenosis
Authors: Do Anh Tien , Nguyen Tran Thuy 
Published: January 2024

The objective of this study evaluated the results of using 3-patch technique for supravalvular aortic stenosis [1]
Methods: This was a review of seri cases: using 3-path technique for supravalvular aortic stenosis from 1/2012 to 12/2018
Results: There were 8 patients who underwent using 3-patch technique, include 5 males and 3 females. The mean of age was 12,4 years (range 4 to 32 year), 7 childrents and 1 adult. The left ventricular outflow tract gradient was 62 mmHg. The time of cardiopulmonary bypass, aortic clamping and ventilator were: 104 minutes; 72 minutes. 7 patients were used pericardium path and 1 patient was another graft. There was not intrahospital mortality. Echocardiography post -operation: left ventricular outflow tract gradient was 11,8 mmHg. During follow-up time 7,8 years after surgery, there was no late death; there were 3 patients who had to reoperation include 2 patient with stenotic distal anastomosis postoperation 5 years and 1 patient with severe aortic valve stenosis postoperation 8 years Conclusion: The long-term of using 3-patch technique for supravalvular aortic stenosis were satisfaction and longer follow-up was essential to find-out about risks of reoperation.
The Craft of Screen Acting
Authors: Brennan Amanda 
Published: January 2024

Have you been working as an actor, but want to refine your craft and take your performance to the next level? Or do you want to transition from stage to screen acting, and secure a role on Netflix?
In this essential book for young working actors, Amanda Brennan offers a specifically psychophysical approach to acting, which provides an understanding of the body as the springboard for creative exploration. Starting with understanding your own instrument, you will learn how to prepare and tune the body for creative work. This is followed by strategies for the refinement of craft, including exercises on voice, movement, character development and rehearsal processes for screen.
Experienced young actors, casting directors and agents such as Asa Butterfield (The Boy in the Striped Pajamas, Hugo, Sex Education), Hannah Rae (City of Tiny Lights), Maisie Williams (Game of Thrones), Daniel Edwards and Christina Shepherd offer their comments and share invaluable advice in interviews throughout the book. With this guide, you will develop a receptive and expressive instrument and be able to build a multi-dimensional character, throughout your career.
A Philosophical History of Police Power
Authors: Lamb Melayna Kay 
Published: January 2024

Rethinking the philosophical grounds of police power, Melayna Lamb argues that traditional ideas of sovereignty and the law need to be radically re-evaluated. In placing police at the centre of analysis this book demonstrates the manner in which police power exists in a complex and overlapping relationship with sovereignty and law in a form which is not reducible to implementation. In doing this it argues for the centrality of order in any consideration of police and challenging a common narrative whereby a dynamic, interventionist sovereign power that follows from a belief of order as ‘artificial’ is replaced by a liberal, limited non-interventionist sovereign power that proceeds from a ‘natural’ order. Moving through thinkers such as Hobbes, Hegel and Adam Smith the book argues that police power is in fact an-archic in form, in a manner that makes it impossible to hold accountable through the law.
Lamb adopts an interdisciplinary approach that turns to philosophy to make sense of global events that see police power at their centre. This includes the history of police brutality in the US, the structural injustices made more apparent by COVID-19 and the growing calls to abolish the police.
Licence to Thrill
Authors: Chapman James 
Published: January 2024

Licence To Thrill is the definitive scholarly study of the full history of the James Bond film series from the first picture, Dr No (1962), to the present. It considers the origins of the films in the spy thrillers of Ian Fleming and examines the production histories of the films in the contexts of the British and international film industries. James Chapman explores how the films have changed over time in response to developments in the wider film culture and society at large. He charts the ever-evolving Bond formula, analysing the films’ representations of nationhood, class and gender in a constantly shifting cinematic and ideological landscape.
Licence To Thrill has been described as an ‘indispensable’ work for film historians and Bond fans alike. For this third edition, Chapman has thoroughly updated the existing content, written a new Introduction and added new chapters on the most recent films – Quantum of Solace, Skyfall, Spectre and No Time to Die - which star Daniel Craig as Bond.
Why We (Still) Need Russian Literature
Authors: Brintlinger Angela 
Published: January 2024

For nearly two centuries readers all over the world have turned to the great canon of Russian literature. Love and death, war and peace, yes, even crime and punishment; readers across the globe have found in Russian writing a substantial measure of intellectual provocation, aesthetic pleasure, emotional resonance, and personal solace. Why We (Still) Need Russian Literature uses a number of Russian authors, from the familiar names of Tolstoy, Dostoevsky and Chekhov to less widely known writers like Goncharov, Bunin and Erofeev, to connect readers with these experiences.
With a lively, jargon-free style and insightful analyses of thought-provoking texts, this concise volume helps you to understand more fully the pleasure to be found in reading by putting you in conversation with some of the Russian masters. Though Russian novels often seem to be as big and potentially dangerous as a brick, this book argues that ‘big’ is in the eye of the beholder; the very definition of a Big Book, as is argued here, being a work of literature that bears reading and rereading, contemplating and discussing. Indeed by demonstrating how to identify what readers seek, and find-from aesthetically pleasing descriptions to apt psychological renderings-in Russian books, Angela Brintlinger seeks to enhance the gratification of reading, giving armchair travelers an excuse to embark on a series of fascinating journeys.
Drawing on Brintlinger’s experiences as a scholar, teacher, and reader of literature, the book is informed by a deep cultural understanding of Russia and Russians. It reveals this through engaging literary meditations that connect Russian literature to those losses, ironies, and ambiguities that define the human condition. More specifically, it will serve as a guide or a prompt to give the Big Books of Russian literature a(nother) chance.
Shirts, Shifts and Sheets of Fine Linen
Authors: Inder Pam 
Published: January 2024

Shirts, Shifts and Sheets of Fine Linen explores how the jobs of the ‘seamstress’ evolved in scope, and status, between 1600-1900.
In the 17th and early 18th centuries, seamstressing was a trade for women who worked in linen and cotton, making men’s shirts, women’s chemises, underwear and baby linen; some of these seamstresses were consummate craftswomen, able to sew with stitches almost invisible to the naked eye. Few examples of their work survive, but those that do attest their skill. They took apprentices and generally made a good living by the standards of their time. However, as the ready-to-wear trade expanded in the 18th century, women who assembled these garments were also known as seamstresses, as were women employed by families to keep the household linen and in good order. By the 1840s, most seamstresses were outworkers for companies or entrepreneurs, paid unbelievably low rates per dozen for the garments they produced, notorious examples of downtrodden, exploited womenfolk.
This book explores the seamstress’s change of status and the reasons for it, and hints at the resurgence of the trade today because so few 21st century women are now individually skilled at repairing and altering clothes. Illustrated with 60 images, the book brings seamstresses into focus as real people, granting new insights into working class life in 18th- and 19th-century Britain.
The Renaissance of Feeling
Authors: Essary Kirk 
Published: January 2024

Offering a re-reading of Erasmus's works, this book shows that emotion and affectivity were central to his writings. It argues that Erasmus's conception of emotion was highly complex and richly diverse by tracing how the Dutch humanist writes about emotion not only from different perspectives—theological, philosophical, literary, rhetorical, medical—but also in different genres. In doing so, this book suggests, Erasmus provided a distinctive, if not unique, Christian humanist emotional style.
Demonstrating that Erasmus consulted multiple intellectual traditions and previous works in his thoughts on affectivity, The Renaissance of Feeling sheds light on how understanding emotions in late medieval and early modern Europe was a multi-disciplinary affair for humanist scholars. It argues that the rediscovery and proliferation ancient texts during the so-called renaissance resulted in shifting perspectives on how emotions were described and understood, and on their significance for Christian thought and practice. The book shows how the very availability of source material, coupled with humanists’ eagerness to engage with multiple intellectual traditions gave rise to new understandings of feeling in the 16th century.
Essary shows how Erasmus provides the clearest example of such an intellectual inheritance by examining his writings about emotion across much of his vast corpus, including literary and rhetorical works, theological treatises, textual commentaries, religious disputations, and letters. Considering the rich and diverse ways that Erasmus wrote about emotions and affectivity, this book provides a new lens to study his works and sheds light on how emotions were understood in early modern Europe.
Multiliteracy Play
Authors: Warner Chantelle 
Published: January 2024

This book proposes to expand multiliteracies frameworks in second language education, by recognizing that learning a new language and culture involves both designs and desires, the affects and emotions that feed our responses to particular ways of making meaning.
Over the past two decades, multiliteracies approaches to second language education have brought attention to the diversity of modes, media, language varieties, and discourses involved in what we often shorthand as language learning. A core concept in these discussions is the idea of meaning design, the idea that languages are dynamic, culturally-shaped systems of resources for engaging with and making sense of the world.
Building on these discussions and drawing inspiration and practical examples from a variety of modern language classes in higher education in the USA, the book demonstrates how poetic and playful language can be embedded in multiliteracies pedagogy in ways that foster learners’ and teachers’ awareness of designs, while also making space for desires that are harder to script or plan for. In addition to building a conceptual map around poetics and play for researchers and teachers in language education, the book offers concrete examples of what a multiliteracies approach emphasizing designs and desires can look like in classrooms and curricula.
The Body Collected in Australia
Authors: Pacitti Eugenia 
Published: January 2024

Offering an insight into 19th- and early 20th-century medical school dissecting rooms and anatomy museums, this book explores how collected human remains have shaped western biomedical knowledge and attitudes towards the body over the past 200 years.
Focusing on specimens collected in Australia, Pacitti asks how and why anatomists and medical students obtained human body parts, and explores the role Australia played in the global narrative of western medical development. Interrogating the relationship between colony and metropole in the circulation of knowledge, it shows how Australia formed a distinct identity as a nation; wanting to conform to established norms in Britain and overseas, but simultaneously pushing against them. Pacitti sheds new light on our understanding of western medical networks, fresh insights into the ongoing challenges historic specimen collections pose, and reveals how these collections remain active pedagogical tools in the present day.
The Body Collected in Colonial Australia is a cultural history of collectors and the collected that deepens our understanding of the ways the living have used the dead to comprehend the intricacies of the human body in illness and health.
Principles of the Law of Agency
Authors: Bennett Howard 
Published: January 2024

The second edition of this successful book provides a fully updated, succinct examination of the principles of agency law.
The book explores the rules of attribution, the rights and obligations arising within the agency relationship, the impact of agency in the fields of contract and tort, and the termination of an agent’s authority. Throughout the book, full consideration is given to the issues arising under the Commercial Agents (Council Directive) Regulations 1993. The discussion is informed not only by common law authority that constantly nourishes the development of agency law principle, but also by international soft law instruments and the Restatement of the Law, Third: Agency.