bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bringing abstract concepts to life: A health humanities–based approach to teaching social determinants of health
Authors: Balhara Kamna S. , Regan Linda , Chopra Eisha , Irvin Nathan 
Published: February 2024

AbstractBackgroundTo address health inequities, emergency physicians must understand the structural underpinnings of health disparities, including social determinants of health (SDoH), and must critically reflect on the integration of SDoH into clinical practice. SDoH education should include reflective knowledge acquisition, while incorporating systemic sociohistorical forces and individual factors, such as bias, which propagate inequities but are rarely emphasized in graduate medical education (GME). The health humanities (HH), an inclusive transdisciplinary field combining arts, humanities, and social justice, may represent a novel unexplored approach toward incorporating SDoH in GME.MethodsWe sought to implement and evaluate a GME HH‐based curriculum focused on SDoH. An interprofessional team applied Kern's framework to create a longitudinal HH curriculum integrating narrative medicine and visual thinking strategies with evidence‐based practices for addressing SDoH in clinical practice. This curriculum was implemented for 52 residents in an EM program in 2019–2020; sessions were initially held in the classroom and community and then virtually during the COVID‐19 pandemic. Objectives included encouraging (1) critical thinking about SDoH, (2) engagement with patients and communities, (3) self‐reflection, and (4) translation of SDoH to patient care. Descriptive statistics and a constructivist paradigm were applied to results of a postcurriculum survey and focus group, respectively.ResultsA curriculum evaluation survey completed by 32/52 residents (61.5%) revealed agreement (75%–90%) that objectives were met. 93.1% of respondents thought humanities were important in residency training. Qualitative analysis of a focus group with 10 participants revealed additional impacts on individual growth, transformation of departmental culture, and transformation of patient care. Curriculum implementation was inexpensive and relied on interprofessional collaboration.ConclusionsThe HH represent a promising collaborative framework for integrating SDoH in GME and may inspire transformation of learners’ attitudes and practices in EM, though clinical impacts still need to be established.
Evaluation of dredge fines material in manufactured soil blends on soil health parameters
Authors: Lake Loryssa M. , Benson Kaitlyn S. , Basta Nicholas T. 
Published: February 2024

AbstractSolutions are needed to address increasing concerns over degraded land and global food insecurity. One solution is to design soil blends that can restore soil quality and fertility. Dredge material has many soil‐like properties, which makes it a good candidate for the main component of manufactured soil blends. Questions have arisen over contaminants of concern (heavy metals and polyaromatic hydrocarbons [PAH]) in dredge fines precluding them from reuse. One approach is to remove the fine fraction of dredge to lower the contaminant concentration; however, it may result in a lower quality soil substitute for land reclamation. In this study, soil blends were designed to compare the use of whole dredge to dredge fines (e.g., dredge with silt and clay fraction) and to assess the benefits of compost material, clay, and fertilizer additions. Dredge fines blends led to increases in soil quality, dry matter growth, plant available water, total and active C, potentially mineralizable N, and micronutrients. The addition of compost material led to better soil quality for a vast majority of the tested parameters. Dredge fines were below regulatory standards for contaminants of concern (e.g., carinogenic polyaromatic hydrocarbon and heavy metals), allowing their reuse in soil blends. Removal of fines from dredge decreases the quality of soil blends and should not be removed from dredge material for use as topsoil or in topsoil blends. The 80% (v/v) dredge fines blend with 20% (v/v) additions of compost material resulted in the greatest improvements in the assessed soil health parameters.
State labeling's impact on geographic boundaries of local
Authors: Fife Kathryn , Secor William , Campbell Benjamin 
Published: February 2024

AbstractLocal labeling is an important issue within the horticultural industry as many producers have devoted considerable resources to advertising their products as local. Further, all states have implemented some form of local labeling program to increase local purchasing. As states expand the reach of these programs, the programs begin to compete as awareness and perception move across state lines. Using an online survey to study consumers in the Southeastern United States, we look to identify how state labeling programs are viewed in nearby states. Notably, we assess awareness, perception, and its impact on the local definition of these programs in their “home” state as well as nearby states. Specifically, we evaluate the impact of nine Southeastern state‐level branding programs. Our results indicate that consumers are more aware of their home state's local label, but awareness does exist for other states' labels. We also find that a home state label moves some consumers to a more state‐level local boundary, while seeing another state's label increases the boundary for what is perceived as local [EconLit Citation: Q13].
INviting Veterans InTo Enrollment in Alzheimer's Disease Research Centers (INVITE‐ADRC): An NIA and VA–sponsored initiative to increase veteran participation in aging and dementia research
Authors: Padula Claudia B. , Ball Sherry , Wyman Mary F. , Evans Kirsten , Grant Harli , Periyakoil Vyjeyanthi S. , Zhu Carolyn W. , Yaffe Kristine , Huang Grant D. 
Published: February 2024

AbstractINTRODUCTIONOlder military veterans often present with unique and complex risk factors for Alzheimer's disease (AD) and related dementias. Increasing veteran participation in research studies offers one avenue to advance the field and improve health outcomes.METHODSTo this end, the National Institute on Aging (NIA) and Department of Veterans Affairs (VA) partnered to build infrastructure, improve collaboration, and intensify targeted recruitment of veterans. This initiative, INviting Veterans InTo Enrollment in Alzheimer's Disease Research Centers (INVITE‐ADRC), provided funding for five sites and cross‐site organizing structure. Diverse and innovative recruitment strategies were used.RESULTSAcross five sites, 172 veterans entered registries, and 99 were enrolled into ADRC studies. Of the enrolled, 39 were veterans from historically underrepresented racial and ethnic groups.CONCLUSIONSThis initiative laid the groundwork to establish sustainable relationships between the VA and ADRCs. The partnership between both federal agencies demonstrates how mutual interests can accelerate progress. In turn, efforts can help our aging veterans.
Polar Aromatic Two‐dimensional Dion‐Jacobson Halide Perovskites for Efficient Photocatalytic H2 Evolution
Authors: Peng Yu , Zhang Yang , Wang Xing , Sui Xin Yuan , Lin Miao Yu , Zhu Yan , Jing Changfei , Yuan Hai Yang , Yang Shuang , Liu Peng Fei , Dai Sheng , Zheng Zhaoke , Yang Hua Gui , Hou Yu 
Published: February 2024

AbstractPolar materials with spontaneous polarization (Ps) have emerged as highly promising photocatalysts for efficient photocatalytic H2 evolution owing to the Ps‐enhanced photogenerated carrier separation. However, traditional inorganic polar materials often suffer from limitations such as wide band gaps and poor carrier transport, which hinders their photocatalytic H2 evolution efficiency. Here, we rationally synthesized a series of isostructural two‐dimensional (2D) aromatic Dion–Jacobson (DJ) perovskites, namely (2‐(2‐Aminoethyl)pyridinium)PbI4 (2‐APDPI), (3‐(2‐Aminoethyl)pyridinium)PbI4 (3‐APDPI), and (4‐(2‐Aminoethyl)pyridinium)PbI4 (4‐APDPI), where 2‐APDPI and 4‐APDPI crystalize in polar space groups with piezoelectric constants (d33) of approximately 40 pm V−1 and 3‐APDPI adopts a centrosymmetric structure. Strikingly, owing to the Ps‐facilitated separation of photogenerated carriers, polar 2‐APDPI and 4‐APDPI exhibit a 3.9‐ and 2.8‐fold increase, respectively, in photocatalytic H2 evolution compared to the centrosymmetric 3‐APDPI. As a pioneering study, this work provides an efficient approach for exploring new polar photocatalysts and highlights their potential in promoting photocatalytic H2 evolution.
Improving the proton conductivity of HKUST‐1 by hole expansion and ionic liquid introduction
Authors: Liu Yu‐Hang , Liu Yeping , Zheng Xiaofeng , Wang Qinghui , Tang Huan , Liu Jie , Ma Yingying , Jing Zhihong , Liu Zhe 
Published: February 2024

As a new type of proton conductor, metal–organic frameworks (MOFs) have attracted much attention because of their superior properties over conventional materials, such as the modifiability of framework, reversibility of coordination bond, high specific surface area, and porosity. It is predicted that the proton conductivities of MOFs can be improved by hole expansion and ionic liquid introduction. In this work, HKUST‐1 and LP‐HKUST‐1 were prepared, which were filled with different proportions of N‐methylimidazole triflate (MIM‐CF3SO3) to prepare composite materials MIM‐CF3SO3@HKUST‐1‐100% and MIM‐CF3SO3@LP‐HKUST‐1‐x (x = 25%, 50%, 75% and 100%). A total of seven kinds of materials were synthesized. The proton conductivities of all the materials at 75% RH were tested from 303 to 353 K. In this environment, MIM‐CF3SO3@LP‐HKUST‐1‐100% shows excellent proton conductivity (σ = 0.341 S·cm−1 at 353 K, 75% relatively humidity [RH]), being 7060 times that of HKUST‐1, and reaches the peak value of MOF family in recent years. Then, the conductivities of parts of the materials were tested in extreme environments, such as in high‐humidity environment (303–353 K, 100% RH), high‐temperature environment (373–423 K, N2 atmosphere), and low‐temperature environment (253–283 K, 75% RH). The results show that under all conditions above, the proton conductivity of MIM‐CF3SO3@LP‐HKUST‐1‐100% is the best, up to 0.341 S·cm−1 at 353 K and 75% RH, 0.179 S·cm−1 at 353 K and 100% RH, 1.31 × 10−3 S·cm−1 at 283 K and 75% RH, and 2.31 × 10−4 S·cm−1 at 423 K and N2 atmosphere, indicating that proton conductivity of HKUST‐1 is improved by hole expansion and ionic liquid introduction. Finally, the stability test showed that MIM‐CF3SO3@LP‐HKUST‐1‐100% was stable in all environments above. Moreover, the conductive mechanism of HKUST‐1 before and after introduction of ionic liquids was also discussed, providing a theoretical basis for the enhancement of proton conductivities of MOFs using ionic liquid introduction and hole expansion.
Current Development of Lanthanide Complexes for Biomedical Applications
Authors: Wang Mengfei , Kitagawa Yuichi , Hasegawa Yasuchika 
Published: February 2024

AbstractLuminescent molecule–based bioimaging system is widely used for precise localization and distinction of cancer/tumor cells. Luminescent lanthanide (Ln(III)) complexes offer long–lived (sub–millisecond time scale) and sharp (FWHM <10 nm) emission, arising from the forbidden 4f–4f electronic transitions. Luminescent Ln(III) complex–based bioimaging has emerged as a promising option for both in vitro and in vivo visualizations. In this mini–review, the historical development and recent significant progress of luminescent Ln(III) probes for bioapplications are introduced. The recent studies are mainly focused on three points: (i) the structural modifications of Ln(III) complexes in both macrocyclic and small ligands, (ii) the acquirement of high resolution luminescence images of cancer/tumor cells and (iii) the constructions of ratiometric biosensors. Furthermore, our recent study is explained as a new Cancer GPS (cancer grade probing for determining tumor grade through photophysical property analyses of intracellular Eu(III) complex.
Behcet disease: A case report on the utilization of T1‐weighted black blood fat‐suppressed sequences for the detection of venous vasculitis
Authors: Weiss Daniel , Appel Elisabeth , Turowski Bernd 
Published: February 2024

Key Clinical MessageT1‐weighted black blood FS sequences may provide a useful addition to imaging protocols in detection of subtle changes in venous vasculitides and, therefore, may have an impact on treatment options.
Addressing elements of white supremacy in counselor education: The path forward for racial justice in the counseling field
Authors: Gorritz Frank 
Published: February 2024

AbstractDespite a perceived post‐racist era prevalent in various forms of social discourse, racial injustice is still perpetuated throughout the United States. This conceptual article explores the ways white supremacy is still prevalent in counselor education as well as ways to disrupt white supremacy in counselor education.
Recent Advances in Palladium‐Catalyzed Asymmetric Heck/Tsuji–Trost Reactions of 1,n‐Dienes
Authors: Zhao Guofeng , Li Wenbo , Zhang Junliang 
Published: February 2024

AbstractTransition–metal catalyzed tandem asymmetric reactions were powerful tools to access various chiral compounds. Many strategies have been developed for the coupling of 1,n‐dienes with aryl halides via a tandem Heck/Tsuji–Trost process. However, the control of regio‐ and stereo‐chemistry remains a challenging task. This minireview details the recent advances in the field of asymmetric Heck/Tsuji–Trost reactions catalyzed by palladium complex, which have opened new opportunities and expanded our understanding in this area of research in recent years.
Pyrrolidium‐ and Imidazolium‐Based Ionic Liquids and Electrolytes with Flexible Oligoether Anions
Authors: Ahmed Mukhtiar , Filippov Andrei , Johansson Patrik , Shah Faiz Ullah 
Published: February 2024

AbstractA new class of fluorine‐free ionic liquids (ILs) and electrolytes based on aliphatic flexible oligoether anions, 2‐(2‐methoxyethoxy)acetate (MEA) and 2‐[2‐(2‐methoxyethoxy)ethoxy]acetate (MEEA), coupled with pyrrolidinium and imidazolium cations is introduced. For the ILs with MEEA anions, Li+ conducting electrolytes are created by doping the ILs with 30 mol % of LiMEEA. The structural flexibility of the oligoether functionality in the anion results in glass transition temperatures (Tg) as low as −60 °C for the neat ILs and the electrolytes. The imidazolium‐based ILs and electrolytes reveal better thermal stabilities but higher Tg and lower electrochemical stabilities than the corresponding pyrrolidinium‐based analogues. All neat ILs show comparable transport properties for the cations and these decrease by the addition of lithium salt – the pyrrolidinium‐based electrolyte being affected the most.
INTEGRAL‐ILCCO cohort data analysis revealed the association of clonal haematopoiesis with an increased risk of lung cancer
Authors: Cheng Chao , Hong Wei , Amos Christopher I 
Published: February 2024

AbstractTo investigate the association between clonal haematopoiesis (CH) and lung cancer risk, we identified CH mutations in 1 059 lung cancer cases and 899 controls using the blood whole‐exome sequencing data generated from the Integrative Analysis of Lung Cancer Etiology and Risk project of the International Lung Cancer Consortium (INTEGRAL‐ILCCO). Based on the variant allele frequency (VAF) of these mutations, we stratified CH carriers into two groups, low VAF (1%–10%) and high VAF (â‰¥10%), respectively. We observed a significant association between the presence of CH mutations and the risk of lung cancer after adjusting for known risk factors (odd ratio, OR = 1.37, 95% confidence interval, CI = 1.02–1.85). Such an association was largely driven by CH mutations with high‐VAF, the OR for high‐VAF CH and low‐VAF CH were 2.54 (1.38–4.93) and 1.14 (0.82–1.6), respectively. Trend analysis indicated a significant dose–response relationship (P trend = 0.004). This association between high‐VAF CH and lung cancer risk remained consistent when subjects were stratified by risk factors or lung cancer histological subtypes. A combination of results from INTEGRAL‐ILCCO, UKBB, and MGBB cohorts resulted in a meta‐analysed OR of 1.36 (95% CI = 1.14–1.62) for all CH carriers and of 1.76 (95% CI = 1.34–2.31) for high‐VAF CH carriers, respectively. In conclusion, our analysis revealed a significant association between CH and increased risk of lung cancer as supported by three independent cohorts.
Cold storage and cryopreservation methods for spermatozoa of the sea urchins Lytechinus pictus and Strongylocentrotus purpuratus
Authors: Vacquier Victor D. , Hamdoun Amro 
Published: February 2024

AbstractBackgroundSea urchins have contributed greatly to knowledge of fertilization, embryogenesis, and cell biology. However, until now, they have not been genetic model organisms because of their long generation times and lack of tools for husbandry and gene manipulation. We recently established the sea urchin Lytechinus pictus, as a multigenerational model Echinoderm, because of its relatively short generation time of 4–6 months and ease of laboratory culture. To take full advantage of this new multigenerational species, methods are needed to biobank and share genetically modified L. pictus sperm.ResultsHere, we describe a method, based on sperm ion physiology that maintains L. pictus and Strongylocentrotus purpuratus sperm fertilizable for at least 5–10 weeks when stored at 0°C. We also describe a new method to cryopreserve sperm of both species. Sperm of both species can be frozen and thawed at least twice and still give rise to larvae that undergo metamorphosis.ConclusionsThe simple methods we describe work well for both species, achieving >90% embryo development and producing larvae that undergo metamorphosis to juvenile adults. We hope that these methods will be useful to others working on marine invertebrate sperm.
The evolution of entomopathogeny in nematodes
Authors: Trejo‐Meléndez V. J. , Ibarra‐Rendón J. , Contreras‐Garduño J. 
Published: February 2024

AbstractUnderstanding how parasites evolved is crucial to understand the host and parasite interaction. The evolution of entomopathogenesis in rhabditid nematodes has traditionally been thought to have occurred twice within the phylum Nematoda: in Steinernematidae and Heterorhabditidae families, which are associated with the entomopathogenic bacteria Xenorhabdus and Photorhabdus, respectively. However, nematodes from other families that are associated with entomopathogenic bacteria have not been considered to meet the criteria for “entomopathogenic nematodes.” The evolution of parasitism in nematodes suggests that ecological and evolutionary properties shared by families in the order Rhabditida favor the convergent evolution of the entomopathogenic trait in lineages with diverse lifestyles, such as saprotrophs, phoretic, and necromenic nematodes. For this reason, this paper proposes expanding the term “entomopathogenic nematode” considering the diverse modes of this attribute within Rhabditida. Despite studies are required to test the authenticity of the entomopathogenic trait in the reported species, they are valuable links that represent the early stages of specialized lineages to entomopathogenic lifestyle. An ecological and evolutionary exploration of these nematodes has the potential to deepen our comprehension of the evolution of entomopathogenesis as a convergent trait spanning across the Nematoda.
Are sub‐alpine species' seedling emergence and establishment in the alpine limited by climate or biotic interactions?
Authors: Dahle Ingrid J. , Gya Ragnhild , Töpper Joachim P. , Vandvik Vigdis 
Published: February 2024

AbstractOne of the ways in which plants are responding to climate change is by shifting their ranges to higher elevations. Early life‐history stages are major bottlenecks for species' range shifts, and variation in seedling emergence and establishment success can therefore be important determinants of species' ability to establish at higher elevations. Previous studies have found that warming per se tends to not only increase seedling establishment in alpine climates but it also increases plant productivity, which could limit establishment success through increased competition for light. Here we disentangle the relative importance of several climate‐related abiotic and biotic factors on sub‐alpine species' seedling emergence and survival in the alpine. Specifically, we test how temperature, precipitation and competition from neighbouring vegetation impacts establishment, and also whether species' functional traits, or strategies impact their ability to colonise alpine locations. We found that our six sub‐alpine study species were all able to recruit from seed in alpine locations under the extant alpine climate, but their emergence was limited by competition from neighbouring vegetation. This indicates that biotic interactions can hinder the range shifts expected as a result of climate warming. Species with a resource conservative strategy had higher emergence in the extant alpine climate than species with a resource acquisitive strategy, and they were largely unaffected by changes in temperature. The resource acquisitive species, in contrast, had faster emergence under warming, especially when they were released from competition from neighbouring vegetation. Our results indicate that competition from the established vegetation is limiting the spread of lowland species into the alpine, and as the climate continues to warm, species with resource acquisitive traits might gain an advantage.
Digitalization concepts in academic bioprocess development
Authors: Habich Tessa , Beutel Sascha 
Published: February 2024

AbstractDigitalization with integrated devices, digital and physical assistants, automation, and simulation is setting a new direction for laboratory work. Even with complex research workflows, high staff turnover, and a limited budget some laboratories have already shown that digitalization is indeed possible. However, academic bioprocess laboratories often struggle to follow the trend of digitalization. Due to their diverse research circumstances, high variety of team composition, goals, and limitations the concepts are substantially different. Here, we will provide an overview on different aspects of digitalization and describe how academic laboratories successfully digitalized their working environment. The key aspect is the collaboration and communication between IT‐experts and scientific staff. The developed digital infrastructure is only useful if it supports the laboratory worker and does not complicate their work. Thereby, laboratory researchers have to collaborate closely with IT‐experts in order for a well‐developed and maintainable digitalization concept that fits their individual needs and level of complexity. This review may serve as a starting point or a collection of ideas for the transformation toward a digitalized laboratory.