bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global epidemiology of breast cancer based on risk factors: a systematic review
Authors: Roheel Amna , Khan Aslam , Anwar Fareeha , Akbar Zunaira , Akhtar Muhammad Furqan , Imran Khan Mohammad , Sohail Mohammad Farhan , Ahmad Rizwan 
Published: October 2023

BackgroundNumerous reviews of the epidemiology and risk factors for breast cancer have been published previously which heighted different directions of breast cancer.AimThe present review examined the likelihood that incidence, prevalence, and particular risk factors might vary by geographic region and possibly by food and cultural practices as well.MethodsA systematic review (2017-2022) was conducted following Preferred Reporting Items for Systematic Reviews and Meta-analyses (PRISMA) guidelines, reporting on epidemiological and risk factor reports from different world regions. Medical Subject Heading (MeSH) terms: “Breast neoplasm” “AND” country terms such as “Pakistan/epidemiology”, “India/epidemiology”, “North America/epidemiology”, “South Africa/epidemiology” were used to retrieve 2068 articles from PubMed. After applying inclusion and exclusion terms, 49 papers were selected for systematic review.ResultsResults of selected articles were summarized based on risk factors, world regions and study type. Risk factors were classified into five categories: demographic, genetic and lifestyle risk factors varied among countries. This review article covers a variety of topics, including regions, main findings, and associated risk factors such as genetic factors, and lifestyle. Several studies revealed that lifestyle choices including diet and exercise could affect a person’s chance of developing breast cancer. Breast cancer risk has also been linked to genetic variables, including DNA repair gene polymorphisms and mutations in the breast cancer gene (BRCA). It has been found that most of the genetic variability links to the population of Asia while the cause of breast cancer due to lifestyle modifications has been found in American and British people, indicating that demographic, genetic, and, lifestyle risk factors varied among countries.ConclusionThere are many risk factors for breast cancer, which vary in their importance depending on the world region. However, further investigation is required to better comprehend the particular causes of breast cancer in these areas as well as to create efficient prevention and treatment plans that cater to the local population.
How is music listening purpose related to stress recovery? – two preliminary studies in men and women
Authors: Song Yichen , Mewes Ricarda , Skoluda Nadine , Nater Urs M. 
Published: October 2023

IntroductionStudies have suggested that listening to music can reduce psychological and biological responses to a stressor. However, it is unclear whether music has the same effect on stress recovery. According to field studies, people commonly use music in daily life for the specific purpose of relaxation. We explored whether individuals who generally use music for relaxation purposes show improved recovery from an acute stressor.MethodsIn two independent studies, twenty-seven healthy female participants (Mage = 24.07) (Study 1) and twenty-one healthy male participants (Mage = 23.52) (Study 2) were separated into two groups based on their frequency of using music for relaxation purposes (low vs. high). All participants underwent a lab-based psychosocial stress test. Subjective stress levels were measured using visual analogue scales. Salivary cortisol and salivary alpha-amylase were measured to assess endocrine and autonomic stress responses, respectively. Subjective stress levels and saliva samples were measured nine times throughout the stress induction and recovery procedure. Chronic stress levels were assessed using the Perceived Stress Scale and the Screening Scale of Chronic Stress.ResultsNo significant differences were observed in subjective stress levels, salivary alpha-amylase activity, or cortisol concentration between the two groups in either of the two studies. Further analyses revealed that among male participants, increased use of music for relaxation purposes was related to more chronic stress levels (t (10.46) = 2.45, p = 0.03, r = 0.60), whereas female participants exhibited a trend in the opposite direction (t (13.94) = −1.92, p = 0.07, r = 0.46).DiscussionContrary to our expectations, the results indicate that habitual music listening for relaxation purposes is not associated with improved recovery from a stressor. However, due to the small sample size, future exploration is necessary to enhance the statistical power of the results of the study.
Associations of intrinsic capacity, fall risk and frailty in old inpatients
Authors: Shen Shanshan , Xie Yanhong , Zeng Xingkun , Chen Lingyan , Guan Huilan , Yang Yinghong , Wu Xiushao , Chen Xujiao 
Published: October 2023

IntroductionThis study explored the associations of intrinsic capacity (IC), fall risk, and frailty in geriatric inpatients.MethodsA total of 703 hospitalized patients aged 75 years or older were recruited for this retrospective observational study from Zhejiang Hospital using a comprehensive geriatric assessment. The IC composite score was constructed from the scores of the Chinese version of the Mini-Mental State Examination, Short Physical Performance Battery, Short Form Mini Nutritional Assessment, 15-item Geriatric Depression Scale, and self-reported hearing and vision impairment. Adverse outcomes were recorded as the fall risk and frailty using the Morse Fall Scale and the Clinical Frailty Scale. Spearman’s correlation coefficient analyses and multivariate logistic regression models were used to explore the associations between IC, high fall risk, and frailty.ResultsDeclined IC composite scores were associated with increased risks of falls [odds ratio (OR) = 0.64, 95% confidence interval (CI): 0.57–0.72] and frailty (OR = 0.45, 95%CI: 0.37–0.54) among older hospitalized patients after adjusting for the related potential confounders. In addition, decreased cognitive, vitality, locomotion, and psychological scores were associated with increased adverse health conditions, with ORs ranging from 0.26 to 0.70. Vision impairment was observed to increase the risk of frailty (OR = 0.42, 95%CI: 0.23–0.76) after adjusting for the related potential confounders.DiscussionThis study indicated that declined IC was associated with fall risk and frailty in older inpatients. Further prospective studies are needed to explore the longitudinal associations between baseline IC and subsequent risk of falls and frailty.
Dynamic variations in and prediction of COVID-19 with omicron in the four first-tier cities of mainland China, Hong Kong, and Singapore
Authors: Ni Xiaohua , Sun Bo , Hu Zengyun , Cui Qianqian , Zhang Zhuo , Zhang Hua 
Published: October 2023

BackgroundThe COVID-19 pandemic, which began in late 2019, has resulted in the devastating collapse of the social economy and more than 10 million deaths worldwide. A recent study suggests that the pattern of COVID-19 cases will resemble a mini-wave rather than a seasonal surge. In general, COVID-19 has more severe impacts on cities than on rural areas, especially in cities with high population density.MethodsIn this study, the background situation of COVID-19 transmission is discussed, including the population number and population density. Moreover, a widely used time series autoregressive integrated moving average (ARIMA) model is applied to simulate and forecast the COVID-19 variations in the six cities. We comprehensively analyze the dynamic variations in COVID-19 in the four first-tier cities of mainland China (BJ: Beijing, SH: Shanghai, GZ: Guangzhou and SZ: Shenzhen), Hong Kong (HK), China and Singapore (SG) from 2020 to 2022.ResultsThe major results show that the six cities have their own temporal characteristics, which are determined by the different control and prevention measures. The four first-tier cities of mainland China (i.e., BJ, SH, GZ, and SZ) have similar variations with one wave because of their identical “Dynamic COVID-19 Zero” strategy and strict Non-Pharmaceutical Interventions (NPIs). HK and SG have multiple waves primarily caused by the input cases. The ARIMA model has the ability to provide an accurate forecast of the COVID-19 pandemic trend for the six cities, which could provide a useful approach for predicting the short-term variations in infectious diseases.Accurate forecasting has significant value for implementing reasonable control and prevention measures.ConclusionsOur main conclusions show that control and prevention measures should be dynamically adjusted and organically integrated for the COVID-19 pandemic. Moreover, the mathematical models are proven again to provide an important scientific basis for disease control.
Curcumin nanoparticles as a natural antioxidant and antimicrobial preservative against foodborne pathogens in processed chicken fingers
Authors: Morsy Mohamed K. , Al-Dalain Sati Y. , Haddad Moawiya A. , Diab Mohamed , Abd-Elaaty Elsayed M. , Abdeen Ahmed , Ibrahim Samah F. , Shukry Mustafa , Banatean-Dunea Ioan , Fericean Liana , Ghamry Heba I. , El-Sayed Amal , Abdelaziz Manal , Kadhim Noor , Elsabagh Rasha 
Published: October 2023

IntroductionCurcumin has highly antimicrobial and antioxidant activities but has poor bioavailability and low solubility in water. The current study aimed to assess curcumin nanoparticles (Curcumin-NPs) antibacterial and antioxidant efficacy against some pathogens in chicken fingers at 4 °C/27 days.MethodsCurcumin-NPs with particle sizes of 80 ± 2 nm were synthesized using a planetary ball-mill and chitosan-gelatin nanoparticle (CS-G-NPs) solution and then placed into chicken fingers at three concentrations, (2, 5, and 10 μg g−1). The physicochemical properties, antioxidant activity, and antibacterial capacity were evaluated.Results and discussionCurcumin-NPs showed high phenolic content (67.48 mg GAE g−1) and antioxidant activity (22.47 μg ml−1) at 10 μg g−1 compared to other concentrations and curcumin bulk. Curcumin-NPs showed noticeably greater antibacterial ability (in vitro) against S. aureus (18 mm), E. coli (15 mm), and B. cereus (13 mm). In challenge studies, Curcumin-NPs effectively inhibited the three inoculated pathogens ~3–4 log CFU g−1; in vivo; in chicken fingers kept for up to 27 days, compared to the control. In curcumin-NPs chicken samples, the contents of thiobarbituric acid reactive substances (TBARS) and total volatile base nitrogen (TVB-N) compared to the control were substantially lower (27 days). TEM analysis provided an estimate of the antibacterial mechanism of Curcumin-NPs. The findings demonstrated that Curcumin-NPs at 10 μg g−1 were more successful in reducing microbial load in chicken fingers as well as improving quality parameters, enhancing shelf life, and reducing lipid oxidation in poultry meat products.
Health and Economic Benefits of Air Pollution Reductions in Vietnam During 2020–2021
Authors: Hoang Le Tu , Duc Vu Tri , Ngoc Vo Van Duc , Truong Ngo Xuan , Thanh Nguyen Thi Nhat , Trang Phan Thi Thu , Saksena Sumeet , Nhung Nguyen Thi Trang 
Published: October 2023

Objectives: This paper explores the potential reduction in the number of deaths and the corresponding economic benefits in Vietnam that could have arisen from the decreased in concentrations of particulate matter with a diameter of 2.5 μm or less (PM2.5) and nitrogen dioxide (NO2).Methods: Using Global Exposure Mortality Models, we estimated the potential health and economic benefits on people aged 25 and above across Vietnam’s 63 provinces. The counterfactual scenario assumed reducing PM2.5 and NO2 concentrations to levels observed during the two COVID-19 epidemic waves in 2021 with national lockdowns and activity restrictions.Results: In 2019, PM2.5 concentrations ranged from 12.8 to 40.8 μg/m3 while NO2 concentrations ranged between 2.9 and 36.98 μg/m3. The reduced levels of PM2.5 and NO2 resulted in 3,807 (95% CI: 2,845–4,730) and 2,451 (95% CI: 2,845–4,730) avoided deaths of adults aged 25 and above due to non-injury-related causes, respectively. Considering that every prevented death represents potential tangible and intangible cost savings, reduced levels of PM2.5 and NO2 concentrations during COVID-19 restrictions would have resulted in economic benefits of $793.0 million (95% CI: 592.7–985.4) and $510.6 million (95% CI: 381.3–634.9), respectively.Conclusion: The COVID-19 lockdown led to decreased PM2.5 and NO2 concentrations, benefiting health and economy in Vietnam. Our findings highlight the potential advantages of implementing air quality control policies in the country.
Which Biomarker(s) Augment the Diagnostic Value of the Positive Exercise Electrocardiography Test: Systemic Inflammatory Index, Plasma Atherogenic Index, or Monocyte/HDL-C Ratio?
Authors: Ergun Gokhan , Demirelli Selami 
Published: October 2023

The exercise electrocardiography test (EET) is still used before coronary angiography in the diagnosis of chronic coronary syndromes. This study aimed to demonstrate the value of the combination of a positive EET with the systemic inflammatory index (SII), the plasma atherogenic index (PAI), and the monocyte/HDL-C ratio (MHR) in the determination of obstructive coronary artery disease (CAD). This single-center, retrospective study included 540 patients who underwent coronary angiography after ETT. The patients were separated into Group 1, comprising 434 patients with normal coronary arteries and non-obstructive CAD, and Group 2, including 106 with obstructive CAD. In Group 2, the patients were separated into SYNTAX ≤ 22 or ≥23. Glucose, low-density lipoprotein, white blood cells, and MHR were determined to be significantly higher in Group 2 (p < 0.05). According to the multivariate logistic regression analysis, age, gender, diabetes mellitus, and low-density lipoprotein were determined to be independent predictors of CAD. In the ROC curve analysis, a cut-off value of 12 for the MHR in the determination of obstructive CAD had a sensitivity of 60.4% and a specificity of 53.0%. The main result of this study was that a high MHR is an indicator of obstructive CAD in patients with positive EET and suspected CAD.
Microbiological Mechanisms for Nitrogen Removal Using Anaerobic Fermentation Liquid from Spent Mushroom Substrates as a Carbon Source
Authors: Chen Ruihuan , Zhang Weihong , Bi Xiaohui , Jin Yan , Yang Yunlong 
Published: October 2023

In wastewater treatment, a low C/N ratio highly inhibits the bioremoval of nitrogen, and commercial external carbon sources are widely used. In order to obtain an economical substitute, fermentation broth of spent mushroom substrates (SMS) was employed here as a carbon source for denitrification in a sequencing batch reactor (SBR). During the domestication process, the SMS fermentation broth-feeding treatment presented comparable nitrogen removal ability (74.44%) with a commercial carbon source group (77.99%). Rhodobacter, Lactobacillus and Pseudomonas were the dominant bacteria in the fermentation broth, and Saccharomycetales Gymnopilus dilepis was the dominant fungi. At the early domestication stage, the relatively high concentration of fermentation broth led to a much lower abundance of typical nitrate reductase genes than the control group. Furthermore, extracellular polymeric substance (EPS) formation was observed in the broth-feeding sample. The microbial structure dynamic was investigated, which showed a high influent effect when 20% fermentation broth was added. As domestication proceeded, similar dominant species in the control and broth-feeding treatments were observed. Overall, SMS fermentation broth can be used as a promising substitute to replace a costly commercial carbon source.
La Mediación Penal: Una propuesta restaurativa para mitigar la violencia de género y pareja en Chile
Authors: González Ramírez Isabel , Vargas Ugalde Johanna 
Published: October 2023

El presente artículo pretende analizar bajo qué condiciones la justicia restaurativa, a través de su mecanismo más usado -la mediación penal-, es una opción válida para mitigar y prevenir las consecuencias de los delitos de violencia de género y pareja en Chile, mejorando la seguridad futura de las víctimas, para lo que se ha usado una metodología cualitativa, exploratoria-descriptiva, que permite identificar los factores que posibilitan u obstaculizan la incorporación de mecanismos restaurativos en el tratamiento de estos delitos, dentro del sistema penal acusatorio y de corte continental chileno, concluyendo que, conforme a la oferta que realiza dicho sistema de orientación punitiva y a los resultados obtenidos respecto a dichos delitos, no se ha logrado obtener los fines preventivos esperados y tampoco se han brindado soluciones reparadoras conforme a las expectativas de las víctimas. Por el contrario, se evidencia un aumento sostenido del índice de delitos de amenazas, lesiones y femicidios, por lo cual parece necesario ofrecer un abordaje integral y sistémico, que prevenga la escalada de violencia y considere los aspectos íntimos y relacionales entre hombres y mujeres. Así, los mecanismos restaurativos, como la mediación penal, emergen como una opción intra-judicial y sustitutiva al proceso penal, sirviendo como complemento y alternativa plausible de reparación.
PRINSIP-PRINSIP DAN KAIDAH TRANSAKSI DALAM EKONOMI SYARI’AH
Authors: Syaripudin Enceng Iip , Konkon Furkony Deni , Maulin Merry , Bisri Hasan 
Published: October 2023

Abstrak

Islam sebagai suatu sistem hidup (Way Of Live), manusia adalah khalifah di muka bumi dan Islam memandang bahwa bumi dengan segala isinya merupakan amanah dari Allah SWT kepada sang khalifah agar dipergunakan sebaik-baiknya bagi kesejahteraan bersama.

Dalam beraktivitas ibadah yang Goer Mahdoh (muamalah), manusia diberi hak untuk berkreasi, kreatif dan melakukan kegiatan apapun yang bisa memberikan kebaikan untuk dirinya dan masyarakat luas, selama tidak melanggar larangan, dan sesuai dengan Prinsip-prinsip ekonomi Syari’ah demi mendapatkan kesejahteraan dunia dan akhirat.

Adapun tujuan yang hendak dicapai dalam penelitian ini adalah: 1) Apa yang dimaksud dengan Prinsip-prinsip dan Kaidah Transaksi dalam Ekonomi Syari’ah . 3). Untuk mengetahui Bagaimana Prinsip-prinsip dan Kaidah Transaksi dalam Ekonomi Syari’ah.

Metode penelitian yang digunakan dalam penelitian ini adalah metode library research atau book survey. Metode library research adalah metode penelitian yang tekhnik pengumpulan datanya dilakukan di lapangan (perpustakaan) dengan didasarkan atas pembacaaan-pembacaan terhadap beberapa literartur yang memiliki informasi serta memiliki relevansi dengan topik penelitian.
Berdasarkan hasil penelitian disimpulkan bahwa peran pemerintah dalam sistem keuangan islam masih kurang dan setengah hati, ini dibuktikan dengan peningkatan dan perkembangan Perbankan Syariah Indonesia yang berdiri sudah 20 tahun, market share hanya bertengger di 3,8 persen saja, Bandingkan dengan negara jiran, Malaysia, market share-nya 25 persen, sebab peran pemerintah didaerah jiran sangat berperan sekali.

Kata Kunci: Prinsif, kaidah, Transaksi, ekonomi syariah
Lise Öğrencilerinin Bilişsel Esneklik ve Problem Çözme Beceri Düzeyleri: Tanımlayıcı ve İlişkisel Bir Çalışma
Authors: BAHADIR YILMAZ Emel , YÜKSEL Arzu 
Published: October 2023

Amaç: Bu çalışmada, lise öğrencilerinin bilişsel esneklik ile problem çözme becerilerinin ve aralarındaki ilişkinin belirlenmesi amaçlanmıştır.
Yöntem: Tanımlayıcı türdeki araştırmanın örneklemini İç Anadolu Bölgesinde bulunan bir Sosyal Bilimler Lisesi'nde öğrenim gören 382 öğrenci oluşturmuştur. Verilerin toplanmasında, Öğrenci Bilgi Formu, Bilişsel Esneklik Ölçeği ve Problem Çözme Envanteri kullanılmıştır. Mann Whitney U ve Kruskal Wallis testleri ile karşılaştırmalar yapılmıştır. Spearman Korelasyon testi ile değişkenler arasındaki ilişki araştırılmıştır.
Bulgular: Öğrencilerin bilişsel esneklik ölçeği puan ortalaması 51.45±8.51’dir. Problem çözme envanteri toplam puan ortalaması 96.43±19.92 olup problem çözme yeteneğine güven boyutu puan ortalaması 31.28±8.84, yaklaşma kaçınma boyutu puan ortalaması 48.29±11.37 ve kişisel kontrol boyutu puan ortalaması 16.85±3.51’dir. Bilişsel esneklik ile problem çözme arasında orta düzeyde ve negatif yönde bir ilişki vardır (r = -0.490, p < 0.01).
Sonuç: Öğrencilerin bilişsel esneklik düzeyleri arttıkça problem çözme becerileri de artmıştır. Bu nedenle lise öğrencilerinin hem bilişsel esneklik düzeylerini hem de problem çözme becerilerini geliştirmek için müdahale programları planlanmalı ve uygulanmalıdır.
Father-Baby Attachment Levels and Influencing Factors
Authors: KOBYA BULUT Hacer , YEŞİLÇİÇEK ÇALIK Kıymet , KORKMAZ YILDIZ Nazende 
Published: October 2023

Objective: The aim of the study was to determine father-infant attachment levels and the affecting factors.
Methods: Descriptive study included 118 fathers of infants between the ages of 6-12 months. Data were collected using the Descriptive Information Form and the Paternal-Infant Attachment Scale (PIAS). Descriptive statistics, independent sample t-tests, Mann-Whitney U test, the Kruskal Wallis test, and Backward Stepwise Regression were used.
Results: The PIAS score average of fathers was 75.22. Fathers with social security and good marital relationships had significantly higher PIAS scores. Changed diapers, bathed, and messaged obtained significantly higher attachment scores than those who did not (p
Ürodinami İşlemine Yönelik Hastaların Anksiyete, Ağrı ve Utanma Düzeylerinin Belirlenmesi
Authors: SEYHAN AK Ezgi , ÇULHA Yeliz , AKAY Seyhan , ÇULHA Mehmet Gökhan , ÖZBAŞ Ayfer 
Published: October 2023

Amaç: Araştırma, hastaların ürodinami işlemine yönelik anksiyete, ağrı ve utanma düzeylerini belirlemek amacıyla planlandı.
Yöntem: Tanımlayıcı-kesitsel türde planlanan araştırmanın örneklemini, bir şehir hastanesinin Üroloji Polikliniği’ne, Mayıs 2022-Ağustos 2022 tarihleri arasında başvuran, ürodinami işlemi planlanan 90 hasta oluşturdu. Veriler, hasta bilgi formu, ağrı, anksiyete ve utanma düzeylerinin değerlendirildiği Visual Analog Scale (VAS) ve Durumluk Kaygı Ölçeği (DKÖ) ile toplandı. Verilerin analizinde tanımlayıcı istatistiksel yöntemler, ağrı, anksiyete, utanma düzeyleri ve DKÖ puan ortalamalarına göre demografik verilerin karşılaştırılmasında Bağımsız Örneklem t Testi, Kruskal-Wallis ve anlamlı sonuçların post-hoc analizi için Mann Whitney-U testi kullanıldı. Araştırmaya başlamadan önce etik kurul ve kurum izni alındı.
Bulgular: Hastaların anksiyete düzeyi puan ortalamasının 4.50±3.42 ağrı düzeyi puan ortalamasının 3.87±3.01, utanma düzeyi puan ortalamalarının 5.40±3.71 olduğu; DKÖ puan ortalamasının 49.80±6.70 olduğu saptandı. Hastaların cinsiyet, medeni durum, çalışma durumu, sigara kullanma durumu, tanı, daha önce ürolojik girişim uygulanma durumu ve ürodinami işlemi ile ilgili bilgi aldığı kaynak ile anksiyete, ağrı, utanma düzeyleri ve DKÖ puan ortalamaları arasında istatistiksel olarak anlamlı farklılık olduğu belirlendi (p