bluuebunny/crossref_metadata_2025_split huggingface dataset:
Healthy Lifestyles and Primary Healthcare
Authors: Tracy Jane , Iacono Teresa 
Published: December 2023

AbstractGood health is important to everyone. Optimal health is central to being able to enjoy the best possible quality of life. No one can fully engage with, participate in, and contribute to their communities while in discomfort, pain, or distress in physical, oral, or mental health. For people with intellectual disabilities, however, sub-optimal health frequently occurs because of a combination of factors relating to their specific disabilities and external factors, such as where they live, who supports them, and challenges faced in accessing health systems.This chapter provides an overview of the implications of poor health and why poor health is often experienced by people with intellectual disabilities. It then focuses on the role of disability support services and individual support staff in contributing to their optimal health through the support provided to individuals and in interactions with health systems. In this chapter, health is discussed in terms of physical, oral, and mental health because of the strong connections between them.
Consistency of the Flat Flow Solution to the Volume Preserving Mean Curvature Flow
Authors: Julin Vesa , Niinikoski Joonas 
Published: December 2023

AbstractWe consider the flat flow solution, obtained via a discrete minimizing movement scheme, to the volume preserving mean curvature flow starting from $$C^{1,1}$$

C

1
,
1

-regular set. We prove the consistency principle, which states that (any) flat flow solution agrees with the classical solution as long as the latter exists. In particular the flat flow solution is unique and smooth up to the first singular time. We obtain the result by proving the full regularity for the discrete time approximation of the flat flow such that the regularity estimates are stable with respect to the time discretization. Our method can also be applied in the case of the mean curvature flow and thus it provides an alternative proof, not relying on comparison principle, for the consistency between the flat flow solution and the classical solution for $$C^{1,1}$$

C

1
,
1

-regular initial sets.
Stability and guaranteed error control of approximations to the Monge–Ampère equation
Authors: Gallistl Dietmar , Tran Ngoc Tien 
Published: December 2023

AbstractThis paper analyzes a regularization scheme of the Monge–Ampère equation by uniformly elliptic Hamilton–Jacobi–Bellman equations. The main tools are stability estimates in the $$L^\infty $$

L
∞

norm from the theory of viscosity solutions which are independent of the regularization parameter $$\varepsilon $$
ε
. They allow for the uniform convergence of the solution $$u_\varepsilon $$

u
ε

to the regularized problem towards the Alexandrov solution u to the Monge–Ampère equation for any nonnegative $$L^n$$

L
n

right-hand side and continuous Dirichlet data. The main application are guaranteed a posteriori error bounds in the $$L^\infty $$

L
∞

norm for continuously differentiable finite element approximations of u or $$u_\varepsilon $$

u
ε

.
Analytical interference of intravascular contrast agents with clinical laboratory tests: a joint guideline by the ESUR Contrast Media Safety Committee and the Preanalytical Phase Working Group of the EFLM Science Committee
Authors: van der Molen Aart J. , Krabbe Johannes G. , Dekkers Ilona A. , Geenen Remy W. F. , Bellin Marie-France , Bertolotto Michele , Brismar Torkel B. , Cadamuro Janne , Correas Jean-Michel , Heinz-Peer Gertraud , Langlois Michel R. , Mahnken Andreas H. , Ozben Tomris , Quattrocchi Carlo C. , Radbruch Alexander , Reimer Peter , Roditi Giles , Romanini Laura , Sebastià Carmen , Simundic Ana-Maria , Stacul Fulvio , Clement Olivier 
Published: December 2023

Abstract
The Contrast Media Safety Committee of the European Society of Urogenital Radiology has, together with the Preanalytical Phase Working Group of the EFLM Science Committee, reviewed the literature and updated its recommendations to increase awareness and provide insight into these interferences.

Clinical relevance statement
Contrast Media may interfere with clinical laboratory tests. Awareness of potential interference may prevent unwanted misdiagnosis.

Key Points
• Contrast Media may interfere with clinical laboratory tests; therefore awareness of potential interference may prevent unwanted misdiagnosis.
• Clinical Laboratory tests should be performed prior to radiological imaging with contrast media or alternatively, blood or urine collection should be delayed, depending on kidney function.
Willingness to participate in combination screening for lung cancer, chronic obstructive pulmonary disease and cardiovascular disease in four European countries
Authors: Behr Carina , Koffijberg Hendrik , IJzerman Maarten , Kauczor Hans-Ulrich , Revel Marie-Pierre , Silva Mario , von Stackelberg Oyunbileg , van Til Janine , Vliegenthart Rozemarijn 
Published: December 2023

Abstract
Objectives
Lung cancer screening (LCS), using low-dose computed tomography (LDCT), can be more efficient by simultaneously screening for chronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD), the Big-3 diseases. This study aimed to determine the willingness to participate in (combinations of) Big-3 screening in four European countries and the relative importance of amendable participation barriers.

Methods
An online cross-sectional survey aimed at (former) smokers aged 50–75 years elicited the willingness of individuals to participate in Big-3 screening and used analytical hierarchy processing (AHP) to determine the importance of participation barriers.

Results
Respondents were from France (n = 391), Germany (n = 338), Italy (n = 399), and the Netherlands (n = 342), and consisted of 51.2% men. The willingness to participate in screening was marginally influenced by the diseases screened for (maximum difference of 3.1%, for Big-3 screening (73.4%) vs. lung cancer and COPD screening (70.3%)) and by country (maximum difference of 3.7%, between France (68.5%) and the Netherlands (72.3%)). The largest effect on willingness to participate was personal perceived risk of lung cancer. The most important barriers were the missed cases during screening (weight 0.19) and frequency of screening (weight 0.14), while diseases screened for (weight 0.11) ranked low.

Conclusions
The difference in willingness to participate in LCS showed marginal increase with inclusion of more diseases and limited variation between countries. A marginal increase in participation might result in a marginal additional benefit of Big-3 screening. The amendable participation barriers are similar to previous studies, and the new criterion, diseases screened for, is relatively unimportant.

Clinical relevance statement
Adding diseases to combination screening modestly improves participation, driven by personal perceived risk. These findings guide program design and campaigns for lung cancer and Big-3 screening. Benefits of Big-3 screening lie in long-term health and economic impact, not participation increase.

Key Points
• It is unknown whether or how combination screening might affect participation.
• The addition of chronic obstructive pulmonary disease and cardiovascular disease to lung cancer screening resulted in a marginal increase in willingness to participate.
• The primary determinant influencing individuals' engagement in such programs is their personal perceived risk of the disease.
Zur Publikationsaktivität der akademischen Chirurgie und Anästhesiologie in Deutschland
Authors: Debus E. Sebastian , Khesrewi-Elshinnawi Nabila , Ghalib Jonas , Grundmann Reinhart T. 
Published: December 2023

Zusammenfassung
Fragestellung
Die publikatorischen Aktivitäten von Chef- und Oberärzten verschiedener operativer Fächer in deutschen Universitätskliniken sollen in einer Literaturübersicht vergleichend dargestellt werden. Die Leistung in der Gefäßchirurgie wird hinterfragt.

Methodik
Ermittelt wurde die Publikationsleistung der Führungsmannschaften von 38 Universitätskliniken für Allgemein- und Viszeralchirurgie, 39 unfallchirurgischen Universitätskliniken, 33 herzchirurgischen Universitätskliniken, 40 neurochirurgischen Universitätskliniken, 39 anästhesiologischen Universitätskliniken sowie der Gefäßchirurgie in 37 Universitätskliniken. Der Beobachtungszeitraum erstreckte sich über 10 Jahre. Erfasst wurden insgesamt 226 Kliniken mit 2849 Chef- und Oberärzten. Die Gesamtsumme der Publikationen betrug 19.461.

Ergebnisse
Die höchste Anzahl an Publikationen pro Mitarbeiter wurde in der Viszeralchirurgie registriert (10,6), die geringste in der Anästhesiologie (3,5). Gravierende Unterschiede zwischen publikationsstarken und -schwachen Kliniken wurden in allen Fachgebieten gesehen. Die Gefäßchirurgie schnitt mit 59,6 % publizierenden Mitarbeitern deutlich ungünstiger ab als z. B. die Neuro- (83,5 %) oder Viszeralchirurgie (79,4 %). Die kumulierten Impact-Faktoren (CIF) pro Mitarbeiter machten diese Fächerunterschiede noch deutlicher.

Folgerung
Die vorliegende Untersuchung demonstriert ein erhebliches Gefälle in der Publikationsaktivität der analysierten Kliniken, dies galt für alle Fächer gleichermaßen, und kann nur mit einer unterschiedlichen Forschungsmotivation erklärt werden. Die Gefäßchirurgie findet sich hinsichtlich der publikatorischen Aktivität in der unteren Hälfte der analysierten Fachgebiete, was aber allein auf der geringen Publikationsaktivität der untergeordneten Organisationsstrukturen beruht.
Implementation of Parenting Programs in Real-World Community Settings: A Scoping Review
Authors: Pinto Rita , Canário Catarina , Leijten Patty , Rodrigo Maria José , Cruz Orlanda 
Published: December 2023

AbstractImplementing parenting programs in real-world community settings is fundamental to making effective programs widely available and consequently improving the lives of children and their families. Despite the literature acknowledging that the high-quality implementation of parenting programs is particularly challenging in real-world community settings, little is known about how the programs are implemented in these settings. This scoping review followed the methodological framework described by the Joanna Briggs Institute to map evidence on how evidence-based parenting programs have been implemented under real-world conditions. A systematic search of 12 scientific databases, gray literature, and the reference lists of the included studies identified 1918 records, of which 145 were included in the review. Fifty-three parenting programs were identified in studies documenting implementation in real-world community settings worldwide. Most studies included families in psychosocial risk engaged with family-support agencies. The qualitative synthesis identified several implementation outcomes, adaptations, barriers, and facilitators. Most studies reported a maximum of two implementation outcomes, mainly fidelity and acceptability. Providers frequently made adaptations, mainly to bring down barriers and to tailor the program to improve its fit. Findings highlight the need for a more detailed description of the implementation of programs, with greater consistency in terminology, operationalization, and measurement of implementation outcomes across studies. This will promote a more transparent, consistent, and accurate evaluation and reporting of implementation and increase the public health impact of parenting programs. Future studies should also assess the impact of adaptations and the cost-effectiveness and sustainability of programs in real-world community settings.
Unlocking potential: Systematic review the use of gamification in leadership curriculum
Authors: Hao Tianshi , Winn Jade G. , Qiang Qiang 
Published: December 2023

AbstractThis systematic review examines the role and efficacy of gamification in leadership education, addressing a significant void in contemporary literature. Recognizing the universally acknowledged significance of leadership in diverse sectors, this study highlights the pervasive challenges in post-secondary leadership curricula, such as unclear objectives, student motivation, lack of access and practical applications. This review dissects gamification's effectiveness, identifies key outcome determinants, and discusses the hurdles to classroom implementation, suggesting potential solutions or interventions by examining 23 peer-reviewed journal articles that are published in various locations and disciplines from 2012–2022. The results cover the roles of digital tools in facilitating gamification, recurring obstacles such as resource limitations, evaluation difficulties, and identifies the challenges in formulating a consensus of an operational definition between scholars. The paper suggests the need for future research focusing on refining gamification's definition, extending its scope, and crafting robust evaluation strategies, thereby catalyzing a transformation in pedagogical practices and should prioritize the development and implementation of robust evaluation strategies for gamified leadership training programs.
Biochemical characterisation of a PL24 ulvan lyase from seaweed-associated Vibrio sp. FNV38
Authors: Rodrigues Valerie J. , Jouanneau Diane , Fernandez-Fuentes Narcis , Onime Lucy A. , Huws Sharon A. , Odaneth Annamma A. , Adams Jessica M. M. 
Published: December 2023

AbstractUlvan is a green macroalgal cell wall polysaccharide that has tremendous potential for valorisation due to its unique composition of sulphated rhamnose, glucuronic acid, iduronic acid and xylose. Several potential applications such as production of biofuels, bioplastics and other value-added products necessitate the breakdown of the polysaccharide to oligomers or monomers. Research on ulvan saccharifying enzymes has been continually increasing over the last decade, with the increasing focus on valorisation of seaweed biomass for a biobased economy. Lyases are the first of several enzymes that are involved in saccharifying the polysaccharide and several ulvan lyases have been structurally and biochemically characterised to enable their effective use in the valorisation processes. This study investigates the whole genome of Vibrio sp. FNV38, an ulvan metabolising organism and biochemical characteristics of a PL24 ulvan lyase that it possesses. The genome of Vibrio sp. FNV38 has a diverse CAZy profile with several genes involved in the metabolism of ulvan, cellulose, agar, and alginate. The enzyme exhibits optimal activity at pH 8.5 in 100 mM Tris–HCl buffer and 30 °C. However, its thermal stability is poor with significant loss of activity after 2 h of incubation at temperatures above 25 °C. Breakdown product analysis reveals that the enzyme depolymerised the polysaccharide predominantly to disaccharides and tetrasaccharides.
Cell wall digestion of the dinoflagellate Breviolum minutum
Authors: Pairs Pranee I. , Dundon Morgan L. , Narváez-Vásquez Javier , Orozco-Cárdenas Martha L. , Xiang Tingting , Jinkerson Robert E. , Rao Masaru P. 
Published: December 2023

AbstractThe mitigation of coral bleaching requires adaptation of its endosymbionts to rising ocean temperatures, acidity, and ultra-violet radiation. While genetic transformation may offer a means for enhancing endosymbiont resilience to these environmental stressors, the opportunity for doing so in dinoflagellates is likely hampered, in part, by their armored cortex, which may present a formidable barrier to intracellular delivery. Here, using Breviolum minutum (Clade B Symbiodiniaceae) as a model, we show that this barrier may be moderated by first disrupting the outer plasma membrane with the detergent octyl β-D-glucopyranoside, followed by enzymatic digestion of the underlying cellulose with Cellulase RS and Macerozyme R-10. Treatment using this new protocol results in 61% reduction in calcofluor-based cell wall staining (i.e., 25% staining for protocol vs. 64% for control), thus demonstrating the ability for considerable cell wall digestion. Furthermore, protoplasts isolated thereby exhibit rapid cell wall recovery, as well as comparable PSII activity and cell growth as the control, thus suggesting that the protocol minimally affects acute- and long-term cellular function. Finally, the isolated protoplasts also show a potentially slight increase in permeability to a model exogenous cargo after electroporation with a non-optimized protocol. Collectively, this constitutes the first known successful generation of viable B. minutum protoplasts, and thus, serves as a foundation for future studies seeking to lower the barrier for transformation of these and possibly other Symbiodiniaceae.
Look in to look out: strategy and family business identity during COVID-19
Authors: Alguera Kleine Rebecca , Ge Bingbing , De Massis Alfredo 
Published: December 2023

AbstractCOVID-19 challenges the value systems of family firms and urges them to adapt their behaviors, affecting their identities. This study aims to explore how and why family businesses strategically respond to challenges to their identity during COVID-19. Based on a qualitative case study of six German family firms, we propose a process model of family business identity variations during COVID-19 with three propositions, highlighting the interplay between strategy and identity. Counterintuitively, we found that an exogenous shock like COVID-19 can have a positive effect on family business identity, leading to identity clarification or consolidation. We contribute to the growing stream of research investigating the impact of COVID-19 on SMEs, as well as research on family business identity heterogeneity and organizational identity literature by illustrating the interplay between strategy and identity.
Statistical inference for discretely sampled stochastic functional differential equations with small noise
Authors: Nemoto Hiroki , Shimizu Yasutaka 
Published: December 2023

AbstractEstimating parameters of drift and diffusion coefficients for multidimensional stochastic delay equations with small noise are considered. The delay structure is written as an integral form with respect to a delay measure. Our contrast function is based on a local-Gauss approximation to the transition probability density of the process. We show consistency and asymptotic normality of the minimum-contrast estimator when a small dispersion coefficient $$\varepsilon \rightarrow 0$$

ε
→
0

and sample size $$n\rightarrow \infty $$

n
→
∞

simultaneously.
Claiming ecological grief: Why are we not mourning (more and more publicly) for ecological destruction?
Authors: Varutti Marzia 
Published: December 2023

AbstractEco-anxiety, grief and despair are increasing, yet these emotions tend to remain private, rarely expressed in public. Why is it important and necessary to grieve for ecological loss? Why are we not—as individuals and societies—coming together to express and share our grief for ecological destruction? I address these questions from three angles. Firstly, I draw on recent literature on ecological grief and prior work on grief for human lives, to argue for the importance and urgency of grieving publicly for ecological loss. Building on this, I identify perceptual, cognitive, affective, ritual and political obstacles to ecological mourning; these obstacles point at critical intersections between emotions, practices, disciplines, public and private realms, which can turn into fruitful venues for further research, debate and action on ecological grief (and its absence). In closing, I propose a set of ‘ecological skills’ that might help us overcome these obstacles, and lead us to embrace ecological grief and mourning as acts of ethical responsibility and care for the planet.
Intraoperative bacterial cultures fail to reliably predict the bacterial spectrum encountered during infectious complications after appendicitis
Authors: Strohäker Jens K. H. , Brüschke Martin J. , Bachmann Robert , Mihaljevic André L. , Ladurner Ruth , Beltzer Christian R. 
Published: December 2023

AbstractAcute appendicitis is a common surgical emergency. Complicated appendicitis usually warrants perioperative antibiotic treatment in order to prevent infectious complications. Whether routine microbiological testing benefits the individual patient is a topic of debate. The goal of our study was to assess perioperative antibiotic prescriptions as well as the benefit of microbiological testing during the appendectomy as a predictor for bacteria encountered in infectious complications. This is a retrospective analysis of 1218 consecutive patients that underwent appendectomy at a tertiary referral center between 2014 and 2021. The patient charts were systematically analyzed regarding intraoperative outcome, microbiologic results, and postoperative infectious complications. 1218 patients were included in this study of which 768 were uncomplicated appendicitis (UA) and 450 were complicated appendicitis (CA). Microbiological testing was performed in 39.2% of UA cases (33.6% of which grew bacteria) compared to 74.9% of CA cases (78.6% positive cultures). The strongest individual predictors for SSI were gangrenous and perforated appendicitis. A total of 58 surgical-site infections developed, of which 49 were intra-abdominal fluid collections or abscesses. Thirty-two patients had revision surgery or CT-guided drainage for SSI. In the cases where microbiological testing was done both during the appendectomy and the SSI, 13/18 showed different bacteria on culture testing. The infectious outcome was favorable in 98.3%. While microbiological testing offers insights into resistance patterns, it is of little benefit for the individual patient, given the low predictive value for bacteria found during SSI. Achieving source control combined with empiric antibiotic coverage leads to favorable outcomes independent of culture results.
Enhancing the Chinese identity of young people in Hong Kong and Macao based on the creation of cinematic virtual reality art, taking the cinematic virtual reality work I love being me: in my place, my home as an example
Authors: Lei Zhiyun , Zhou Wen , Yang Xifan , Zhou Jiongsheng 
Published: December 2023

AbstractThe subject of this paper is the use of cinematic virtual reality (CVR) to study the issue of Chinese identity. Guided by theories of immersion and presence, taking a cultural perspective (collective memory) on the context of the relationship between mainland China, Hong Kong, and Macao, we created a CVR work titled I Love Being Me: in my Place, my Home. We used CVR as a stimulus for an experiment with the aim of proving that CVR has a significant effect on enhancing the sense of Chinese identity in young people in Hong Kong and Macao. Based on the results of the experiment, we draw the following two conclusions: (1) CVR provides participants with a greater sense of immersion and presence compared to traditional 2D films; (2) CVR should be tailored to local culture—identity, history, language and politics—to maximize participants’ sense of identity and immersion.