bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlation of lifestyle behaviors during pregnancy with postpartum depression status of puerpera in the rural areas of South China
Authors: Ding Ye , Li Genyuan , Shi Xi , Wang Mengyi , Peng Yanxia , Deng Huiqin , Yang Ziqi , Liang Qingfen , Wang Zhixu 
Published: December 2023

BackgroundPostpartum depression (PPD) is among the most common postpartum complications. Its prevalence is associated with strong regional variability. Women in rural areas of China have a high risk of PPD. The aim of this study was to investigate the PPD status of women in rural South China and explore the effects of modifiable lifestyle behaviors during pregnancy on their PPD status, thereby providing a scientific basis for the prevention and intervention of PPD in rural China.MethodsA cohort study was conducted on 261 women from four maternal health institutions situated in rural areas of Guangdong Province and the Guangxi Zhuang Autonomous Region from October 2021 to December 2022. The questionnaires were administered to these women to obtain data about sociodemographic characteristics, health literacy, physical activity during pregnancy, and sleep and dietary status during pregnancy, as well as depression status on the 42nd day after delivery. The lifestyle behaviors during pregnancy and the PPD status of the study population were analyzed. Multiple linear regression models were used to determine the correlation between lifestyle behaviors and PPD status. Path analysis was performed to explore the interaction between various lifestyle behaviors.ResultsA total of 14.6% of women had a PPD status. Women who continued to work during pregnancy had an Edinburgh Postpartum Depression Scale (EPDS) score of 1.386 points higher than that of women who did not (В = 1.386, β = 0.141, p = 0.029). For every 1-point increase in the infant feeding-related knowledge score and pregnancy diet diversity score, the EPDS score decreased by 0.188 and 0.484 points, respectively, and for every 1-point increase in the Pittsburgh sleep quality index score, the EPDS score increased by 0.288 points. Age was related to infant feeding-related knowledge (indirect path coefficient = 0.023). During pregnancy, sedentary time was correlated with sleep quality (indirect path coefficient = 0.031) and employment status (indirect path coefficient = 0.043).ConclusionEmployment status, infant feeding-related knowledge, sleep quality, and diet diversity during pregnancy directly influenced the PPD status, while age and sedentary time during pregnancy indirectly influenced the PPD status. Promoting healthy lifestyle behaviors, including reducing sedentary time, improving sleep quality, and increasing dietary diversity, may be effective in reducing PPD occurrence.
Factors influencing the 5-year survival rate of oral cancer patients in the Mongolian population: a retrospective cohort study
Authors: Davaatsend Oyuntsetseg , Altannamar Munkhdul , Batbayar Badral , Jagdagsuren Urjinlkham 
Published: December 2023

IntroductionThe high mortality rate of head and neck cancers, particularly oral cancer, poses a significant health challenge in developing nations such as Mongolia. This retrospective survival analysis study was conducted to identify factors influencing the 5-year survival rate of oral squamous cell carcinoma patients.MethodsThe study analyzed data from 173 patients diagnosed with oral squamous cell carcinoma, including multiple variables such as age, gender, residence, education, tobacco and alcohol consumption, oral health indicators, family history, precancerous conditions, cancer characteristics, treatment, rehabilitation, cancer recurrence, and 5-year survival. Survival analysis was conducted using the Kaplan–Meier method, and STATA was used for statistical analysis.ResultsThe study revealed a 5-year survival rate of 50.3% for oral cancer patients, with a survival rate of 38% for tongue cancer patients. Age, residence, cancer stage, and cancer recurrence were identified as significant survival predictors. Compared to those aged 60 or younger, the hazard ratio (HR) for patients aged 61 or older was 1.52. Survival was associated with female gender (HR = 0.47, CI = 0.29–0.77). Urban residence was associated with decreased survival (HR = 1.92, CI = 1.22–3.05). Significantly worse survival was associated with the presence of cancer recurrence (HR = 1.99, CI = 1.15–3.04). Oral cancer patients in stage IV had a fourfold higher risk of mortality compared to those in stage I (HR = 4.08, CI = 1.2–13.84).ConclusionThis research highlights the influence of age, urban habitation, and cancer recurrence on oral cancer survival. Age, urban residence, and cancer recurrence were all associated with decreased survival, whereas cancer at stage IV substantially increased the risk of death. The significance of early detection, treatment, and active surveillance to identify oral cancer at an early stage is highlighted by these findings. Compared to industrialized nations, Mongolia's lower oral cancer survival rates emphasize the need to increase public awareness and education. A comprehensive approach is required to improve oral cancer patient survival rates and quality of life, including emphasizing early detection through active surveillance, implementing preventive measures, and advancing cancer education initiatives.
Development and characterization of an immortalized swine respiratory cell line for influenza A virus research
Authors: Neasham Peter J. , Pliasas Vasilis C. , North J. Fletcher , Johnson Celeste , Tompkins S. Mark , Kyriakis Constantinos S. 
Published: December 2023

IntroductionSwine serve as an important intermediate host species for generating novel influenza A viruses (IAVs) with pandemic potential because of the host’s susceptibility to IAVs of swine, human and avian origin. Primary respiratory cell lines are used in IAV research to model the host’s upper respiratory tract in vitro. However, primary cell lines are limited by their passaging capacity and are time-consuming for use in industry and research pipelines. We were interested in developing and characterizing a biologically relevant immortalized swine respiratory cell line that could be used for efficient propagation and characterization of swine IAV isolates.MethodsLung tissue for the generation of primary swine respiratory cells were isolated from the bronchi of an 8-week-old Yorkshire/Hampshire pig, which were immortalized by transduction of the SV40 T antigen using a lentivirus vector. The transduction of the SV40 T antigen was confirmed by Real Time RT-PCR in cells passaged greater than twenty times.ResultsImmortalized swine respiratory cells expressed primarily α2,6 sialic acid receptors and were susceptible to both swine and human IAVs, with swine viruses exhibiting higher replication rates. Notably, infection with a swine H3N2 isolate prompted increased IL-6 and IL-1α protein secretion compared to a seasonal human H3N2 virus. Even after 20 passages, the immortalized cells maintained the primary respiratory cell phenotype and remained permissive to IAV infection without exogenous trypsin.DiscussionIn summary, our developed immortalized swine respiratory cell line offers an alternative in vitro substrate for studying IAV replication and transmission dynamics in pigs, overcoming the limitations of primary respiratory cells in terms of low passage survivability and cost.
Preclinical research in paclitaxel-induced neuropathic pain: a systematic review
Authors: Bacalhau Carolina , Costa-Pereira José Tiago , Tavares Isaura 
Published: December 2023

IntroductionChemotherapy-induced peripheral neuropathy (CIPN) is a common consequence of cancer treatment and pain is a frequent complaint of the patients. Paclitaxel, a cytostatic drug, generates a well-described peripheral nerve injury and neuroinflammation, which may be experimentally mimicked in animal models. We conducted a systematic review analyzing the experimental design, reporting and mechanisms underlying paclitaxel-induced neuropathy in the included studies to establish the perspectives of translation of the current literature in models of CIPN.MethodsWe elected studies published in Pubmed and Scopus between 1 January 2018 and 3 December 2022.ResultsAccording to a defined mesh of keywords searched, and after applying exclusion and inclusion criteria, 70 original studies were included and analyzed in detail. Most studies used male Sprague-Dawley rats to induce paclitaxel-induced neuropathy, used low doses of paclitaxel, and the analyzed studies mainly focused at 14-28 days of CIPN. Mechanical nociceptive tests were preferred in the behavioral evaluation. The mechanisms under study were mainly neuroinflammation of peripheral nerves. The overall methodological quality was considered moderate, and the risk of bias was unclear.DiscussionDespite the ample preclinical research in paclitaxel-induced neuropathy, this systematic review alerts to some flaws in the experimental design along with limitations in reporting, e.g., lack of representation of both sexes in experimental work and the lack of reporting of the ARRIVE guidelines. This may limit the reproducibility of preclinical studies in CIPN. In addition, the clinical features of CIPN should be considered when designing animal experiments, such as sex and age of the CIPN patients. In this way the experimental studies aiming to establish the mechanisms of CIPN may allow the development of new drugs to treat CIPN and translation in the research of CIPN could be improved.
Gender and Age Influence on Emergency Department Visits for Non-Suicidal Self-Injuries in School Aged Children in Italy: An 11 Years Retrospective Cross-Sectional Study
Authors: Paladini Giovanni , Sciurpa Elena , Onorati Roberta , Elhadidy Heba Safwat Mhmoued Abdo , Giacomini Gianmarco , Mamo Carlo , Borraccino Alberto 
Published: December 2023

Objectives: Non-suicidal self-injury (NSSI) poses a threat in developmental ages, yet there is a scarcity of studies on NSSI trends, especially those in emergency departments (ED).Methods: The aim of this cross-sectional study is to describe trends in ED visits for NSSI among young people aged between 5 and 19 years in Italy from 2011 to 2021 in Piedmont. From the ministerial ED discharge information system, all occurring NSSIs were identified by medical report and/or ICD9CM code and reported as a population rate and a visit rate on all ED requests.Results: The general rate of ED visits remained stable, with around 210,000 (55% males) visits each year, along the whole period from 2011 to 2019, then halved during 2020 and 2021. The NSSI population and visits rates increased from 2013, peaking in 2019 at a rate of around 25 and 23 NSSI visits (girls) and 76 and 69 NSSI (boys) per 100,000 ED visits. In 2020 and 2021, the rate of NSSI visits increased, particularly in girls and among older adolescents.Conclusion: The gradual increase of NSSI over the last decade is a rising public health issue, which deserves wider attention to ensure early detection and prevention.
Síndrome Coronariana em pacientes pós-transplante cardíaco: uma análise de literatura
Authors: Vilhena Danilo Vilela , Pedrosa Daniel Faria , Machado Altielly Montes , Castro Isabella Netto de Almeida , Ferreira Leonardo Jorge Monteiro , De Almeida Amanda Costa , Itagiba Iury Pacheco , Freitas Pedro Henrique de Oliveira Langoni Ribeiro , Benedeti Rafaela Reusing , Rocha Manuella Correa Barrias Nara , Milão Marttina Rossi , Do Prado Fellype Matos , Almeida Arthur Barbosa Silva 
Published: December 2023

O transplante cardíaco ortotópico segue como o tratamento de escolha para pacientes com insuficiência cardíaca refratária às alternativas de tratamento convencionais farmacológicas. Todavia, por conta do recebimento de um órgão geneticamente diferente, necessitando de medicações imunossupressoras e, em alguns casos, indivíduos que já possuem fatores de riscos para desenvolvimento de doenças cardiovasculares, surge o questionamento sobre a probabilidade desses pacientes transplantados sofrerem de Síndrome Coronariana Aguda (SCA), além de avaliar sua morbimortalidade quando comparado aos pacientes não transplantados. Objetivo: Investigar, interpretar e revisar os achados sobre Síndrome Coronariana Aguda em pacientes pós-transplante cardíaco, quanto também aos sinais e sintomas que podem aparecer nessas situações. Metodologia: Utilizou-se a base Medical Literature Analysis And Retrieval System Online (MEDLINE/PubMed), sob os descritos heart transplant & acute coronary syndrome, com seleção de artigos de revisão e artigos originais, seguidos critérios de elegibilidade. Foram encontrados 388 textos, com seleção inicial de 171, dos quais restaram 32 elegíveis. Resultados: Os artigos redigidos em língua inglesa, contemplavam publicações de autores e periódicos de diferentes nacionalidades. A maioria dos artigos abrangia o ano de 2021 (11), sendo grande parte publicada entre os anos de 2020 e 2022. Considerações finais: Os estudos demonstraram que não houve correlação do transplante cardíaco com aumento direto da incidência de síndrome coronariana aguda, no entanto, uma das complicações tardias mais observadas do transplante cardíaco é a Doença Vascular do Enxerto (DVE), cursando com estenose dos vasos coronarianos, sendo assim, um grande risco à SCA, logo, entende-se que o risco à essa cardiovasculopatia aumenta indiretamente.
Perfil epidemiológico de pacientes com Sepse em Alagoas: uma análise de 2016-2020
Authors: Calixto Gabriel Ferreira de Oliveira , De Oliveira Arlete Bulhões Cavalcanti Madeiro , Da Costa Renata Nobre , Oliveira Bruna Tavares , Eugênio Igor Guedes , Pascoal David Balbino , De Araújo Isabela Macêdo , De Almeida Ana Carolina Medeiros 
Published: December 2023

Objetivo: Este estudo teve como objetivo traçar o perfil epidemiológico de pacientes com sepse entre os anos de 2016 a 2020 em Maceió, Alagoas. Metodologia: Estudo descritivo epidemiológico, realizado em Maceió, a partir do Sistema de Informações Hospitalares do Sistema Único de Saúde (SIH/SUS), no período de 2016 a 2020, e das seguintes variáveis: Cor/raça, sexo e idade. Resultados: Foram realizadas tabelas para facilitar a análise e comparação dos dados. Infere-se que a maioria das internações por sepse em Alagoas foram realizadas em Maceió, sendo majoritariamente em indivíduos de idade inferior a cinco anos, pardos e homens; com exceção de 2020, em que a população feminina internada superou a masculina. Conclusão: Tendo em mente que a maioria dos casos tanto em Alagoas como na sua capital são de crianças e idosos do sexo masculino e pardos, medidas poderão ser tomadas para prevenção de novos casos e para o direcionamento da conduta intra-hospitalar.
Revisão de literatura: os benefícios da educação sexual nas escolas
Authors: Firme Laura Santos , Rezende Matheus Ennes de Faria , Villela Pedro Almeida Santos , Neves Rillari Tawana Silveira , Quintão Crislian Silveira Reis 
Published: December 2023

A educação sexual nas escolas, aborda tópicos como anatomia, fisiologia, orientação sexual e relacionamentos e a legislação brasileira influencia diretamente nessa dinâmica, tornando-a mandatória para os currículos. O atual estudo revisa a literatura existente a respeito dos efeitos pessoais e sociais da Educação Sexual e sua relevância, por meio da revisão de 9 artigos das bases de dados Scielo, PubMed e LILACS. E as pesquisas bibliográficas revelam evidências de que a educação sexual reduz taxas de gravidez na adolescência e ISTs, promove a aceitação da diversidade sexual e também previne abuso sexual infantil e atua na melhora inclusividade da comunidade LGBTQIA+. Entretanto existem desafios para a plena aplicação desse ensino, como o preconceito em relação a ele e o despreparo das redes de ensino. Apontando-se a necessidade de fortalecer a Educação Sexual no Brasil, visto dados alarmantes sobre violência sexual e de gênero, violências essas com severos impactos psicológicos, sexuais e sociais.
ANALISIS RASIO KEUANGAN SEBAGAI ALAT UNTUK MENILAI KINERJA KEUANGAN PADA BUMDESA DHARMA KARYA
Authors: Sari Dewi Mertyani , Ratih Komang Ayu Maryuni , Kasih Ni Luh Sri 
Published: December 2023

Penelitian ini dilakukan untuk melihat dan menilai kinerja keuangan melalui rasio likuiditas, rasio leverage, dan rasio rentabilitas pada BUMDes Dharma Karya. Subjek penelitian ini adalah laporan keuangan BUMDes Dharma Karya periode 2017-2021. Data sekunder merupakan data yang digunakan dalam penelitian ini. Analisis penelitian ini menggunakan analisis deskriptif kuantitatif berupa analisis rasio keuangan berdasarkan Peraturan Menteri Negara Koperasi dan Usaha Kecil dan Menengah Republik Indonesia nomor 06/Per/M.KUKM/V/2006. Hasil penelitian memuat (1) berpedoman pada rasio likuiditas memperoleh skor 156,554% termasuk dalam kriteria cukup baik yang berarti BUMDes dapat dikatakan cukup mampu memenuhi utang lancarnya (2) berpedoman pada rasio leverage, rasio total hutang terhadap total aset, yaitu 47,91%, memiliki kategori keduanya, yang berarti bahwa total aset/aset di BUMDes mampu berkontribusi terhadap total utang BUMDes serta bertanggung jawab atas kewajiban (3) berdasarkan rasio rentabilitas dilihat dari pengembalian aktiva sebesar 4,12% termasuk dalam kriteria cukup baik artinya BUMDes sudah mampu produktif dalam menghasilkan laba.
ANALISIS KINERJA KEUANGAN PEMERINTAH PADA BADAN KEUANGAN KABUPATEN LIMA PULUH KOTA
Authors: Safitri Annisa Desi , Putri Lodia Dwika , Zaharman Zaharman 
Published: December 2023

The purpose of this research is to find out and analyze the government's financial performance in the Fifty Cities Regency Finance Agency in 2017-2021 by using the ratio of degrees of fiscal decentralization, the ratio of independence, the ratio of PAD effectiveness, the ratio of efficiency, and the ratio of activity.The object of this research is the Budget Realization Report obtained from the Fifty Cities District Finance Agency, the type of data used is quantitative data in the form of a report on the realization of the Fifty Cities District budget for 2017-2021. Data sources are primary data and secondary data. Data collection techniques are observation, documentation, literature studies and interviews.The results of the study show that based on data analysis and discussion that has been carried out the government's financial performance at the Lima Puluh Kota Regency Financial Board seen from the Ratio of the Degree of Fiscal Decentralization and the Ratio of Regional Financial Independence are still in the "very less" category, the Effectiveness Ratio is in the "effective" category, the Ratio Efficiency in the "less efficient" category was only "efficient" with a percentage of 70% in 2018, the Activity Ratio in operating expenditures was in the "good" category, and in capital expenditures it was in the "bad" category.

Keywords: Analysis, Financial Performance, and Government
PENGARUH HYGIENE MAKANAN TERHADAP KUALITAS MAKANAN BREAKFAST PADA RESTORAN THE AXANA HOTEL PADANG
Authors: Fitri Denisa , Asnur Lise 
Published: December 2023

The purpose of this study was to analyze the effect of food hygiene on food quality at The Axana Hotel Padang. This type of quantitative research with a causal relationship approach. The sampling method is non-probability sampling using saturated sampling. The research instrument is a questionnaire equipped with Likert scale. From the results of the study it was concluded that food hygiene (X) showed a percentage of 41% in the range ≥ 69 - < 70 included in the good category. food quality (Y) shows a percentage of 53% in the range ≥ 40 - < 41 included in the good category. Simple linear regression test with the T test on the food hygiene variable affects the food quality variable at The Axana Hotel Padang. The F test value of the food hygiene variable (X) has a significant effect on the quality of food at The Axana Hotel Padang. Adjustment value. R square of 0.284 means that the food hygiene variable has an effect of 28.4% on the quality of food at The Axana Hotel Padang and 71.6% is influenced by other variables.

Keywords: food hygiene, food quality, The Axana Hotel Padang
PENGARUH HARGA DAN KUALITAS PELAYANAN TERHADAP LOYALITAS DI MEDIASI OLEH KEPUASAN PELANGGAN PADA JASA TRANSPORTASI PT. FAJAR RIAU WISATA DUMAI-PEKANBARU
Authors: Nisyah Habibah Tun , Isyandi B. , Wijayanto Gatot 
Published: December 2023

This study aims to see and determine the direct and indirect effects of price and service quality on loyalty mediated by customer satisfaction. The population in this study are customers (passengers) of PT. Fajar Riau Tourism, totaling 19,876 by using a questionnaire. This research is a quantitative research with a descriptive design. The method used in this study aims to see the relationship between variables by using probability sampling which gives equal opportunities for each element of the population to be selected as members of the sample. With the criteria for passengers who are over 17 years old and have used transportation services more than once. Determination of the sample in this study using the tables of Isaac and Michael from certain populations with a level of 10%. Price has a significant positive effect on customer satisfaction and customer loyalty. Service quality has a significant positive effect on customer satisfaction and customer loyalty. Customer satisfaction has a significant positive effect on loyalty. Customer satisfaction is able to mediate the effect of price on loyalty. Customer satisfaction is able to mediate the effect of service quality on loyalty.
Keywords: Price, Service Quality, Customer Satisfaction and Loyalty
Le Roi Lear comme objet de médiation culturelle : une pièce accessible ?
Authors: Dumot Méline 
Published: December 2023

Cet article a pour objet deux mises en scène du Roi Lear, jouées en 2023. Toutes deux sont des versions considérablement abrégées de la pièce de Shakespeare. L’une est une version amatrice jouée en quarante minutes et intitulée King Lear (approximately), par le théâtre du Sycomore de Tournon-sur-Rhône (Ardèche). L’autre, One Shot Shakespeare: King Lear! d’une durée d’une heure quarante a été montée en quatre jours par Irina Brook et sa compagnie dans le théâtre élisabéthain du château d’Hardelot (Nord-Pas-de-Calais). Ces deux adaptations, considérées sous l’angle de l’intermédialité, nous invitent à réfléchir à la rencontre entre publics et acteurs dans une dynamique de médiation culturelle, en nous concentrant notamment sur le passage du texte shakespearien sur scène au moyen de la réécriture, de la traduction, de la mise en espace et de l’interaction avec les spectateurs.