bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Psychotropic Medications Taken by Pregnant Women on Newborn Medical Condition and Lactation Method
Authors: Yoshino Yuta , Yagi Toru , Tsubouchi Koichi , Takaishi Yusuke , Ozaki Yuki , Iga Jun‐ichi , Matsubara Keiichi , Matsubara Yuko , Uchikura Yuka , Sugiyama Takashi , Ueno Shu‐ichi 
Published: January 2025

ABSTRACTBackgroundMaternal psychiatric condition during the perinatal period is relevant to children's cognitive development and mental health. Psychotropic medications are necessary to maintain the mental health of pregnant women with psychiatric disorders, but they are often avoided due to concerns about adverse effects, such as congenital malformations and abnormal neurodevelopment. A retrospective study of pregnant women with psychiatric disorders using psychotropic medications was performed to clarify maternal and child demographic data and to investigate whether psychotropic medications affected the Apgar score and the decision to breastfeed.MethodsData of pregnant women with psychiatric disorders who were referred from the Department of Obstetrics and Gynecology to the Department of Neuropsychiatry at Ehime University Hospital from January 2014 to December 2022 were collected retrospectively. Pearson's chi‐squared test and multiple regression analysis were used for statistical analyses.ResultsA total of 226 women were included; 194 gave birth at our hospital, of whom 79 (40.7%) were taking psychotropic drugs at the time of delivery. None of the children had malformations. There was no relationship between the use of psychotropic medications and the choice to breastfeed. Multiple regression analysis showed that only the gestational weeks at birth were significantly associated with birth weight (p < 0.001) and Apgar score (1 min: p = 0.030; 5 min: p = 0.044).ConclusionsThe use of psychotropic medications during the perinatal period appears safe and beneficial for both pregnant women with psychiatric disorders and their children, and breastfeeding should be considered even if the mother continues to take the medication. To clarify these points, prospective studies using large samples from several countries are needed.
Exploring the Adsorption Features of Furan and 1,n‐Dioxane as Environmental Toxins on Two‐Dimensional RuC Nanosheet: A DFT Study
Authors: Mahmoud Amna H. M. , Aziz Muhrail E. S. , Rabee Abdallah I. M. , El‐Tayeb Mohamed A. , Mekhemer Gamal A. H. , Shoeib Tamer , Ibrahim Mahmoud A. A. 
Published: January 2025

AbstractThe potential of the two‐dimensional ruthenium carbide (RuC) nanosheet to detect highly toxic environmental compounds – namely, Furan (Fur) and 1,n‐Dioxane (1,n‐Diox) – was investigated utilizing the density functional theory (DFT) approach. The adsorption features of the Fur and 1,n‐Diox molecules on the RuC nanosheet were evaluated in parallel and vertical configurations. From energetic manifestations, Fur and 1,n‐Diox molecules preferred to be adsorbed in the parallel configuration rather than the vertical one on the RuC nanosheet with negative Eads values of −27.80 and −9.30 kcal/mol, respectively, for Fur⋅⋅⋅RuC complexes. Bader charge findings demonstrated an electron‐accepting property for the Fur and 1,n‐Diox molecules during the adsorption process over the RuC nanosheet, as indicated by positive Qt values. From the FMO findings, the EHOMO and ELUMO values of Fur/1,n‐Diox molecules, and the pure RuC nanosheet varied considerably after the adsorption process in both configurations. The band structure and TDOS/PDOS plots of Fur/1,n‐Diox⋅⋅⋅RuC complexes showed new bands and peaks for the RuC nanosheet after the adsorption process, proving the capability of the RuC nanosheet to detect the investigated small molecules. The outcomes of the current work can serve as a foundation for using the RuC nanosheets to detect highly toxic small molecules.
Improved starch adhesives for packaging and wood products
Authors: Lin Wei‐Shu , Catchmark Jeffrey M. 
Published: January 2025

AbstractThis study addresses the growing demand for sustainable and non‐toxic adhesives by developing a polysaccharide polyelectrolyte complex (PPC) adhesive using starch polyelectrolytes. A turbidity test was used to formulate the starch PPC, which demonstrated significant improvements in water and grease resistance through the complexation of anionic and cationic starches, with water resistance increasing by 93.2%. Applying 10 g/m2 of starch PPC provided adequate adhesion strength for paper substrates and achieved a joint strength of approximately 4.5 MPa on wood. However, no significant differences were observed between starch PPC and neat starch for wood adhesion, highlighting inadequate bonding. While starch PPC showed enhanced water resistance, bonded wood samples had superior wet strength with cationic starch due to ionic pairing between the starch and wood. Contact angle measurements revealed lower wettability of starch PPC on wood, indicating weaker surface attachment and adhesion strength. These results emphasize the need for further optimization of starch‐based adhesives to improve their performance while maintaining environmental sustainability.Highlights
UV–Vis light transmittance optimizes starch‐based PPC composition.
Shear‐thickening behavior was detected in starch both before and after complexation.
Starch PPC showed a 93.2% improvement in water resistance versus neat starch
Starch PPC demonstrates adequate strength as an effective paper adhesive.
Starch PPC adhesive achieved a shear strength of 4.5 MPa with wood substrates.
Computational and experimental mapping of the allosteric network of two manganese ABC transporters
Authors: Duman Ozge , Kuznetsova Anastasiya , Levanon Nurit Livnat , Grupper Moti , Ersoy Akarun Ayca , Acar Burcin , Kessel Amit , Ben‐Tal Nir , Lewinson Oded , Haliloglu Turkan 
Published: January 2025

AbstractTransition metals (e.g., Fe2/3+, Zn2+, Mn2+) are essential enzymatic cofactors in all organisms. Their environmental scarcity led to the evolution of high‐affinity uptake systems. Our research focuses on two bacterial manganese ABC importers, Streptococcus pneumoniae PsaBC and Bacillus anthracis MntBC, both critical for virulence. Both importers share a similar homodimeric structure, where each protomer comprises a transmembrane domain (TMD) linked to a cytoplasmic nucleotide‐binding domain (NBD). Due to their size and slow turnover rates, the utility of conventional molecular simulation approaches to reveal functional dynamics is limited. Thus, we employed a novel, computationally efficient method integrating Gaussian Network Models (GNM) with information theory Transfer Entropy (TE) calculations. Our calculations are in remarkable agreement with previous functional studies. Furthermore, based on the calculations, we generated 10 point‐mutations and experimentally tested their effects, finding excellent concordance between computational predictions and experimental results. We identified “allosteric hotspots” in both transporters, in the transmembrane translocation pathway, at the coupling helices linking the TMDs and NBDs, and in the ATP binding sites. In both PsaBC and MntBC, we observed bi‐directional information flow between the two TMDs, with minimal allosteric transmission to the NBDs. Conversely, the NBDs exhibited almost no NBD‐NBD allosteric crosstalk but showed pronounced information flow from the NBD of one protomer towards the TMD of the other protomer. This unique allosteric “footprint” distinguishes ABC importers of transition metals from other members of the ABC transporter superfamily establishing them as a distinct functional class. This study offers the first comprehensive insight into the conformational dynamics of these vital virulence determinants, providing potential avenues for developing urgently needed novel antibacterial agents.
From Saying to Communicating: The Generic Development of Classroom Academic Presentations by Chinese First‐Year College Students
Authors: Ma Junming , Liu Chengyu 
Published: January 2025

ABSTRACTClassroom academic presentation (CAP) has been perceived as an important academic genre integral to college learners' academic success. However, the schematic structure of CAP and learners' acquisition of it remain unclear. In this study, we identified its schematic structure with the method of metagenres and investigated L2 learners' generic progression in employing the genre by examining the generic structures of 39 CAPs delivered by a cohort of Chinese undergraduate learners over a semester. The results show that the learners manifest an unequal development in the CAP generic structure, and they weave the interpersonal meaning inappropriately later into the structure than the ideational one. Our findings offer a reference model for the schematic structure of CAP, help identify obstacles to learning the genre, and have important implications for teaching.
The Intersection of Gender and National Identity in History Textbooks in Kazakhstan
Authors: Bekzhanova Zhazira , Durrani Naureen 
Published: January 2025

Abstract
The history curriculum and textbooks are central to nation-building projects, as school history aims to transmit historical knowledge and create a shared desired national identity particularly in newer nation-states. Although the nation is imagined as a community of equals, national identity is constructed through power relations since it structures the representations of the nation around conceptions of masculinityand femininity. The analysis of school history textbooks is important, as they are a key cultural resource that pupils use to learn about “doing gender” and to develop their national consciousness. This chapter analyzes the construction of gender and national identities in the history textbooks, a compulsory subject taught across all secondary schools. Data sources include seven textbooks recommended by Kazakhstan’s Ministry of Education and Science, covering 7th to 11th grades used in Kazakh medium schools. The history textbooks for 9th and 11th grades consist of two volumes each. The study employs quantitative and qualitative methods to analyze the interrelated constructs of gender as category, construction, and deconstruction. The findings reveal four key observations: the prevalence of male dominance and the invisibility of female icons in national historiography, the perpetuation of hegemonic masculinities, the normalization of idealized femininities, and instances of gender transgression.
Challenges of Arbitration in the Western Balkans
Authors: Meskic Zlatan 
Published: January 2025

Abstract
The Western Balkan States have enormous potential to further develop arbitration as the most attractive method of alternative dispute resolution. The courts in this region are overburdened. The litigation in commercial cases takes too long. Arbitration should benefit from the lack of efficiency in litigation, but it does not. This paper aims to determine the challenges for arbitration in the Western Balkans to reach its full potential. Besides some legislative restrictions, the paper identifies gaps in legal education as one of the important reasons behind the small number of cases before local arbitration institutions. While it is true that arbitration institutions should do more to keep their arbitration rules attractive, this is usually not the reason for parties not to choose arbitration. The stakeholders simply lack awareness of all the benefits of arbitration. The expertise is present only in small circles of professionals, making it difficult to promote the use of arbitration for a broader audience.
Expanding the Dispute Resolution Toolbox for Investment Disputes: Opportunities for Dispute Prevention and Mediation in the Western Balkans
Authors: Brodlija Fahira 
Published: January 2025

Abstract
The multiple ongoing reform processes of investment law and investor-State dispute settlement (ISDS) opened the space to reconsider the default reliance on investment arbitration and to reimagine the role of dispute prevention and amicable settlement mechanisms in this space. Such mechanisms entail several benefits for States, including cost and time efficiency, more leverage and control in the course and outcome of disputes, and the restoration of trust in ISDS more broadly. Dispute prevention mechanisms and mediation have emerged as viable reform options, gaining growing support from States (including the EU and its Member States), investors, and international organizations (UNCITRAL, the World Bank Group, etc.) alike. While dispute prevention mechanisms take different shapes and forms in different countries, amicable settlement (including negotiations, conciliation and mediation) has been available in international investment treaties for decades, in the so-called “cooling-off” period. Nevertheless, it has not been effectively used in ISDS, due to a variety of factors, ranging from the preference for third-party adjudication, motivated by the desire of the competent authorities to avoid personal liability resulting from settlements with foreign investors, and/or a lack of capacities. The Western Balkans governments, navigating the ISDS reform process, while progressing on their path to EU accession, are a good case study for the challenges and opportunities of integrating dispute prevention and mediation into the State toolbox for investment dispute resolution. This chapter will address the regional and international, as well as legal and institutional frameworks for dispute prevention and mediation, the obstacles and challenges in the Western Balkans, and the emerging new structures and best practices, which establish a promising model for the region, with tailored solutions for each State. The chapter will offer perspectives for dispute prevention and mediation as staples of the investment protection frameworks in the Western Balkans on their path to the EU, and as future EU Member States.
Plea Bargaining and Guilty Plea as Negotiated Justice Instruments in Macedonian Criminal Trials
Authors: Lažetić Gordana , Misoski Boban 
Published: January 2025

Abstract
The authors elaborate on the practical implementation of the two newly enacted elements for negotiated justice within the Macedonian criminal procedure. In this occasion, the authors perform research of the practical implementation of the sentence bargaining and guilty plea in front of the courts for the period of seven years. Authors conclude that instead of having a wider use of these negotiated instruments in practice and by that improving the efficiency and efficacy of the Macedonian courts, the contrary situation can be observed, as the number of cases resolved through these instruments are declining. The chapter analyses the reasons for such situation and provides theoretical and practical possible solutions for improvement of the observed trend in the use of these negotiated justice instruments.
Some Peculiarities of the Legal Framework on Commercial Arbitration in Bosnia and Herzegovina
Authors: Grbo Zinka , Halilović Sevleta 
Published: January 2025

Abstract
In Bosnia and Herzegovina, arbitration emerges as a promising mechanism for resolving disputes, especially those involving foreign parties. Nevertheless, an overview of the legal framework shows several obstacles that impede this from becoming a reality. Upon examination of the legal framework, a patchwork of laws governing arbitration, dispersed across B&H’s territorial units, is revealed. However, even fragmented, this framework provides a solid ground for arbitration proceedings to be conducted. This is shown by analyzing certain aspects of arbitration, including arbitrability, arbitrator appointments, arbitration agreements, and awards, shedding light on both strengths and weaknesses. Although there is room for improvement in the legal framework, its current deficiencies cannot be the sole reason why arbitration proceedings rarely occur in B&H. The paper also explores the current state of play of institutional arbitration, through the analysis of the Court of Arbitration attached to the Foreign Trade Chamber of Bosnia and Herzegovina, identifying areas for improvement. Ultimately, the authors advocate for a human-centered approach to arbitration reforms, emphasizing clarity, efficiency, and accessibility. By addressing the system’s challenges with empathy and pragmatism, B&H can unlock the full potential of arbitration as a cornerstone of dispute resolution.
Challenges in the Process of Recognition and Enforcement of Foreign Arbitral Awards in the Republic of North Macedonia
Authors: Kocev Ljuben 
Published: January 2025

Abstract
Arbitration is increasingly becoming the preferred method for the resolving of international cross-border disputes among business persons. One of the main advantages of arbitration is that arbitral awards are more easily recognized and enforced than judicial awards, mainly due to the New York Convention. Consequently, the process of recognition and enforcement of foreign arbitral awards has a pivotal role in facilitating international trade and investment by providing a mechanism that enables the parties to easily enforce awards rendered in arbitration proceedings. In the Republic of North Macedonia, as in many countries of the Western Balkans, arbitration is still in its early stages, and arbitration practice remains relatively low. As a result, arbitration-related issues pose challenges to national courts and all relevant stakeholders. While national courts have a pro-arbitration attitude, there were some instances in the past where the courts, and the legal system at large, have failed to adhere to international standards to the detriment of the parties involved in the arbitration process. The chapter aims to provide an analysis of the challenges that have arisen in the past concerning the recognition and enforcement of arbitral awards, through the analysis of the laws and procedures related to the process, as well as an analysis of relevant case law.
Decentral Implementation of EU International Investment Protection Policy and Its Implications for Countries in the Western Balkans
Authors: Böhme Bianca 
Published: January 2025

Abstract
This chapter examines the decentralized implementation of EU international investment protection policy and its implications for Western Balkan countries. With the Treaty of Lisbon granting the EU exclusive competence over foreign direct investment, a new centralized approach was adopted. However, due to the stagnation of EU-level agreements, investment protection increasingly relies on Member States’ BITs, overseen by the European Commission. The chapter explores how this shift affects Western Balkan countries, especially those aspiring EU accession. It discusses the necessary alignment of BITs with evolving EU standards, including substantive and procedural changes, and the broader implications for investment treaty practices in the region. The analysis highlights the challenges faced by these countries in harmonizing their agreements with EU policies and the potential impact on their accession processes.
Unitarity and Strong Graded Locality of Holomorphic Vertex Operator Superalgebras with Central Charge at Most 24
Authors: Gaudio Tiziano 
Published: January 2025

Abstract
We prove that all nice holomorphic vertex operator superalgebras (VOSAs) with central charge at most 24 and with non-trivial odd part are unitary, apart from the hypothetical ones arising as fake copies of the shorter moonshine VOSA or of the latter tensorized with a real free fermion VOSA. Furthermore, excluding the ones with central charge 24 of glueing type III and with no real free fermion, we show that they are all strongly graded-local. In particular, they naturally give rise to holomorphic graded-local conformal nets. In total, we are able to prove that 910 of the 969 nice holomorphic VOSAs with central charge 24 and with non-trivial odd part are strongly graded-local, without counting hypothetical fake copies of the shorter moonshine VOSA tensorized with a real free fermion VOSA.
Predictors and Implications of Myocardial Injury in Intracerebral Hemorrhage
Authors: Hess Felix , McGinnis Julian , Baki Enayatullah , Wiltgen Tun , Müller Arne , Maegerlein Christian , Kirschke Jan , Zimmer Claus , Hemmer Bernhard , Wunderlich Silke , Mühlau Mark 
Published: January 2025

Abstract

Purpose
Myocardial injury, indicated by an elevation of high-sensitive cardiac Troponin (hs-cTnT), is a frequent stroke-related complication. Most studies investigated patients with ischemic stroke, but only little is known about its occurrence in patients with intracerebral hemorrhage (ICH). This study aimed to assess the frequency, predictors, and implications of myocardial injury in ICH patients.

Methods
Our retrospective analysis included 322 ICH patients. We defined myocardial injury as an elevation of hs-cTnT above the 99th percentile (i.e. 14 ng/L). Acute myocardial injury was defined as either a changing pattern of > 50% within 24 h or an excessive elevation of initial hs-cTnT (> 52 ng/L). 3D brain scans were assessed for ICH visually and quantitatively by a deep learning algorithm. Multiple regression models and Voxel-based Lesion-Symptom Mapping (VLSM) were applied.

Results
63.0% (203/322) of patients presented with myocardial injury, which was associated with more severe strokes and worse outcomes during the in-hospital phase (P < 0.01). Acute myocardial injury occurred in 24.5% (79/322) of patients. The only imaging finding associated with acute myocardial injury was midline shift (69.8% vs. 44.6% for normal or stable hs-cTnT, P < 0.01), which also independently predicted it (odds ratio 3.29, confidence interval 1.38–7.87, P < 0.01). In contrast, VLSM did not identify any specific brain region significantly associated with acute myocardial injury. Acute myocardial injury did not correlate with preexisting cardiac diseases; however, the frequency of adverse cardiac events was higher in the acute myocardial injury group (11.4% vs. 4.1% in patients with normal and/or stable patterns of hs-cTnT, P < 0.05).

Conclusion
Myocardial injury occurs frequently in ICH and is linked to poor outcomes. Acute myocardial injury primarily correlates to space-occupying effects of ICH but is less dependent on premorbid cardiac status. Nonetheless, it is associated with a higher rate of adverse cardiac events.
Aktuelles zu chirurgischen Therapieoptionen bei chronisch-entzündlichen Darmerkrankungen
Authors: Kneist Werner 
Published: January 2025

Zusammenfassung
Im Bereich der chirurgischen Behandlung chronisch-entzündlicher Darmerkrankungen (CED) gibt es national und international Leitlinien und Entwicklungen, die zu einer besseren Versorgung der Patienten beitragen. Die wichtigen Empfehlungen beziehen sich zunehmend auf individualisierte und minimal-invasive Ansätze mit Integration neuer Techniken. Die Indikation zur abdominellen Operation bleibt an eine Spezialisierung gebunden, nicht zuletzt um Sequenztherapie und Multimodalität in ihrer Bedeutung für die Risikominimierung und Ergebnisverbesserung auch weiterhin einschätzen zu können. In der vorliegenden Arbeit sollen zentrale chirurgische Aspekte der CED Therapie kurz vorgestellt und aktuell eingeordnet werden.