bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidence of Different Characters of Neuropathic Pain in Cancer Patients Coming to Tertiary Care Centre in North India Over A Period of 1 Year – An Observational Study
Authors: Singh Shipra , Dhiraaj Sanjay , Shamshery Chetna , Singh Shalini , Singh Anjali , Kumar Rajput Abhishek , Mishra Prabhaker 
Published: February 2024

Objectives:
Pain is classified as nociceptive, neuropathic, or nociplastic. Neuropathic pain presents as variable phenotypes (characters) based on specific aetiology and pathophysiology. This study aimed to find out among cancer patients the incidence of different phenotypes of neuropathic pain and form specific phenotypic clusters based on the underlying neurophysiology and association of sensory profile with various organ systems – A prospective observational study.

Materials and methods:
The Institutional Ethical Committee clearance (IEC code: 2020-49-MD-EXP-15) https://ctri.nic.in/Clinicaltrials/showallp.php?mid1=44886&EncHid=88651.15716&userName=CTRI/2020/09/027964 approval was obtained. After written and informed consent, patients of age group 18–80 years, registering in the pain and palliative outpatient department or radiotherapy department with complaints of pain and not taking any anti-neuropathic pain medications, were enrolled. They were assessed using Leeds assessment of neuropathic symptoms and signs (LANSS) pain score, and a score of >12 was eligible for assessment of neuropathic pain phenotypes.

Results:
Out of 210 cancer patients complaining of pain, a neuropathic component with LANSS >12 was found in 73 (34.76%). The most predominant phenotypes, allodynia> tingling> pricking = burning, were found in 72.60%, 56.16%, and 43.84% of patients, respectively. Phenotypes were clustered into Nodes 1 and 2 based on clinically significant separation of phenotypes. Node 1 had neuropathic pain of spontaneous origin found predominantly in gastrointestinal tract (GIT) and genitourinary tract (GUT) cancers. Node 2 had stimulus-evoked negative and positive characters which occurred in head and neck, thoracic, and spinal metastatic cancers.

Conclusion:
Careful patient assessment reveals the incidence of neuropathic pain in 34.76%; allodynia and tingling astable the most prominent phenotypes. Broadly, sensory characters were clustered into spontaneous and stimulus-evoked sensations with GIT and GUT cancers presenting with Node 1 symptoms.
A Study of Blood Viscosity and Inflammatory Biomarkers’ Levels in Bilateral Primary Varicose Veins/Reticular Veins as Predictive Markers
Authors: Urvendra Dahiya Mukul , Singh Sanjay , Singh Saurabh , Kumar Singh Santosh , Kumar Varsha 
Published: February 2024

Objectives
Cross-sectional data was collected for a period of 1 year to assess the biomarkers of inflammation, and blood viscosity as predictive markers in patients with primary bilateral varicose veins or reticular veins that might progress to varicose veins.

Material and Methods
A sample of 40 participants, 20 controls and 20 patients aged 18–65 years falling under the reticular veins and symptomatic varicose veins (C1, 2s), primary etiology (Ep), superficial veins (As), reflux pathology (Pr) categories of Clinical, etiologic, anatomic, Pathophysiologic (CEAP) classification with the exception of telangiectatic veins, were included in the study. Blood viscosity was measured using a Capillary Viscometer. Evaluated inflammatory markers were tissue Plasminogen Activator (tPA), Plasminogen Activator Inhibitor-1 (PAI-1), and fibrinogen. Analysis was done using Statistical Package for the Social Sciences (SPSS) software and Chi-square, Fisher’s, Bonferroni, and Analysis of Variance (ANOVA) tests were applied.

Results
There was a statistically insignificant relationship between occupation and different study groups. Standing hours and serum fibrinogen levels had a significant difference in different study groups. Serum tPA, Serum PAI-1, and blood viscosity had an insignificant difference between different study groups. It was revealed that the pairwise group comparisons of study group C2 vs. control group C0, study group C1 vs. control group C0 and study group C2 vs. study group C1, and study group C2 vs. control group C0 each were significantly different pairwise.

Conclusion
Blood viscosity, tPA and PAI-1 cannot be used as predictive markers in patients with bilateral (B/L) primary varicose veins/reticular veins. Serum fibrinogen levels can be used as predictive markers for the development of B/L primary varicose veins and in our particular study with a predictive range of 189.4–327.9 mg/dL but not for B/L reticular veins. Prolonged standing, irrespective of the occupation of the patient, is associated with the development of B/L reticular veins and B/L varicose veins.
The start-up of a neurosurgical service in an East Indonesian archipelagic province: The first 2-year experience of North Maluku Database in Neurosurgery (NOMADEN)
Authors: Nugroho Aryandhito Widhi 
Published: February 2024

Background:
Despite encouraging developments after its initial founding in Indonesia more than seven decades ago, inequity in access and availability of neurosurgical services throughout the country continues to pose a challenge. We aimed to elaborate on the start-up of a previously inactive neurosurgical service in North Maluku, an archipelagic province in East Indonesia, and describe cases managed within the first two years of service.

Methods:
In the North Maluku Database in the Neurosurgery register, demographic and clinical information of neurosurgical patients admitted to Chasan Boesoirie General Hospital, Ternate, from January 2021 to December 2022, were analyzed. Surgically managed patients were rendered visually according to their decades of life and districts of events.

Results:
There were 998 new patients (mean age ± standard deviation [SD]: 34.7 ± 19.6 years, 60.3% male) managed and 216 neurosurgical procedures (mean age ± SD: 33 ± 20.4 years, 67.1% male) performed. The majority of patients operated were within the 1st decade of life (18.5%), presented to the emergency room (56.5%), covered by national health insurance (69.4%), from outside Ternate (62.5%), diagnosed with neurotrauma (40.7%), and discharged alive (80.1%). Ternate was the only district where all seven types of neurological diseases were encountered. No surgeries were performed for patients from Taliabu, the farthest district from Ternate.

Conclusion:
A large portion of neurosurgical patients in North Maluku were those young and at productive age who were transported from outside Ternate with acute neurological disease (particularly neurotrauma). Distance and geographical circumstances may have a profound effect on access to neurosurgical services.
FUNÇÃO SOCIAL E SOLIDÁRIA DA EMPRESA: UM OLHAR NA PERSPECTIVA DA OBSOLESCÊNCIA PROGRAMADA COMO INSTRUMENTO DE BIOPODER
Authors: Duarte Pereira Murai Ana Cristina , Tamer Sergio Victor 
Published: February 2024

Neste artigo, investigou-se o estudo da função social e solidária da empresa, correlacionando-a com a obsolescência programada como mecanismo de biopoder. A empresa deve pautar-se em suas atividades de acordo com a função social e solidária, visando ao desenvolvimento da sociedade. Contemporaneamente, empresas têm praticado a obsolescência programada em busca do crescimento econômico. Nesse sentido, lançou-se, neste estudo, o seguinte problema de pesquisa: a utilização da obsolescência programada como mecanismo de biopoder ofende o Princípio da Função Social e Solidária da empresa, consagrados na Constituição Federal? Para responder o problema proposto, estabeleceu-se como objetivo geral analisar a obsolescência programada praticada pelas empresas como instrumento de biopoder. Utilizaram-se, para a pesquisa proposta neste trabalho, o método dedutivo e a técnica de pesquisa bibliográfica. E essa pesquisa justifica-se em virtude de a utilização da obsolescência programada pelas empresas trazer impactos negativos à sociedade, principalmente ao consumidor e ao meio ambiente. Concluiu-se que a prática da obsolescência, nas relações de consumo pelas empresas, como mecanismo de biopoder, fere os princípios da função social e solidária da empresa.
Optimasi Kinerja Panel Surya Monocrystalline dan Polycrystalline dengan Pengendali MPPT pada Berbagai Tingkat Iradiasi dan Temperatur: Studi Simulasi dengan Matlab
Authors: Fikri Hafidz Saeful , Nugroho Dedi , Jati Budi Pranomo 
Published: February 2024

Dalam upaya mengatasi kelemahan energi konvensional dan mengatasi kekhawatiran global mengenai perubahan iklim, penggunaan sumber energi terbarukan, seperti energi surya, menjadi semakin penting. Tujuan dari penelitian ini adalah untuk menjelaskan seberapa baik kinerja panel surya saat terkena fluktuasi radiasi dan suhu. Pemodelan matematika simulink Matlab akan dimanfaatkan bersama dengan maximum power point tracking (MPPT) untuk menghasilkan daya keluaran yang optimal. Saat mengukur panel surya dengan kapasitas 100 watt, keluaran daya untuk sistem monocrystalline dan polycrystalline masing-masing adalah 85 watt dan 78,2 watt; ketika MPPT diterapkan, angka tersebut meningkat menjadi 103,3 watt dan 94,4 watt. Dengan kapasitas 250 watt, daya yang dihasilkan sebesar 168 Watt untuk monocrystalline dan 126,1 watt untuk polycrystalline. Setelah diterapkan MPPT, dayanya naik menjadi 205,3 watt dan 155,3 watt. Oleh karena itu, diketahui bahwa perangkat monocrystalline memiliki daya keluaran yang lebih tinggi dan radiasi matahari memengaruhi seberapa besar daya yang dihasilkannya. Berdasarkan hasil penelitian, integrasi MPPT dengan algoritma P&O bertujuan untuk meningkatkan efisiensi sistem PV dengan memastikan bahwa daya yang dihasilkan selalu berada pada titik maksimal dengan meningkatkan daya rata-rata sebesar 11 % pada kapasitas 100 watt dan 20 % pada kapasitas 250 watt.
Análise do Regime Internacional de Controle sobre Drogas a partir da perspectiva da Teoria Crítica das Relações Internacionais
Authors: Gonçalves Higor de Souza , Martinez Elias David Morales 
Published: February 2024

O regime internacional de controle sobre drogas vigente desde 1961 a partir das convenções sobre drogas da ONU tem se mostrado ineficaz em concretizar seus objetivos e gerado inúmeros impactos sociais, econômicos e ambientais. Através de um breve levantamento histórico é possível perceber o contexto e os interesses adjacentes sob os quais esse regime se construiu, sendo a política externa dos EUA permeada pelo moralismo de suas elites internas uma das principais razões que levou o regime a adotar uma abordagem criminalizante. Analisando-se o tema a partir da Teoria Crítica das Relações Internacionais é possível perceber que as Ideias possuem um papel central na definição do papel social das drogas e que as Instituições e Capacidades Materiais representam importantes instrumentos para enraizar Ideias no sistema que sejam compatíveis com os interesses do poder hegemônico. Novas Ideias sobre o papel social das drogas, conflitantes com o regime criminalizante, têm ganhado força atualmente e colaborado para a construção de um regime mais coeso, contudo, para gerarem mudanças mais efetivas precisam se inserir com mais força nas Instituições internacionais.
The Brazilian Mathematics Educator Ubiratan D’Ambrosio in vídeos
Authors: Neves Fraz Joeanne , Barbosa de Moura Ellen Michelle , Gomes dos Santos Karla Vanessa , Moreira Geraldo Eustáquio 
Published: February 2024

The aim of this article, of a qualitative approach and descriptive-exploratory nature, was to analyze the contribution of audiovisual material made available on the YouTube platform with the participation of Ubiratan D'Ambrosio on Ethnomathematics. The procedure was a survey and selection of audiovisual material on YouTube with a speech by D'Ambrosio that included the subject of Ethnomathematics and with more than 5,000 views. Six videos, which were made available between 2013 and 2020, were selected. They have a duration varying between five minutes and two hours. The audiovisual material available contains conceptualization and discussion of Ethnomathematics, in addition to the possibility of access and comprehension in a distinctive manner utilizing digital media. According to the theorist, and based on the video analysis, Ethnomathematics is a cultural construction carried out by different groups in their daily lives in the search for survival and transcendence. The importance of digital media as a means of access to information and democratization of knowledge is also emphasized.
Health in All Policies and intersectorality in Latin America and the Caribbean, 2011 - 2021: a scoping review
Authors: Escobar Díaz Fabio Alberto , Rodriguez Corredor Zuly Andrea 
Published: February 2024

Introduction: Intersectoriality, since the Alma Ata Conference in 1978, has become a fundamental part of the political discourse on public health, social determinants, and health promotion to address health problems in society. Following the above, it is important to identify the research carried out in Latin America and the Caribbean on this topic in the last decade.
Metodology: A scoping review was carried out on the scientific evidence published between 2011 and 2021 in countries of the Latin American region on experiences and intersectoral actions between health and other sectors to address joint public health problems.
Results: 15 studies were included; mostly from Brazil, with predominantly qualitative designs and local character. In addition, some analyses highlight the hegemony of the biomedical model, as well as the conflicts and tensions at the ideological level in certain health issues and traditional practices that limit effective intersectoral collaboration. Conclusions: Intersectoriality is not a strictly technical issue, but ideological elements converge that determine its scope and limitations. Studies in countries such as Colombia should be expanded to have evidence that allows an understanding of the barriers and facilitating aspects of intersectorality.
Dostępność wydarzeń naukowych organizowanych przez polskie uczelnie w perspektywie udziału osób niepełnosprawnych oraz innych osób ze szczególnymi potrzebami
Authors: Paluszek Karolina 
Published: February 2024

Dostępność uczelni w Polsce wzrasta w ostatnich latach. Liczne projekty w zakresie dostępności architektonicznej, cyfrowej oraz komunikacyjno-informacyjnej są realizowane w wielu ośrodkach akademickich. Niemniej, z reguły dotyczą one zapewnienia dostępności odbiorcom kształcenia (a więc studentom, słuchaczom studiów podyplomowych, doktorantom), natomiast potrzeby nauczycieli akademickich oraz badaczy są w nich marginalizowane bądź pomijane.
Uczestnictwo w wydarzeniach naukowych stanowi jedną z podstawowych aktywności podejmowanych w ramach działalności naukowej. Czynny udział podejmowany już przez studentów, ale przede wszystkim przez pracowników naukowych, daje możliwość konfrontacji poglądów z innymi osobami, wymiany doświadczeń oraz dyskusji o pomysłach, a tym samym umożliwia rozwój nauki.
W niniejszym artykule omówiono wyzwania związane z uczestnictwem w wydarzeniach naukowych osób ze szczególnymi potrzebami. Autorka analizuje prawne aspekty zagadnienia oraz przedstawia wyniki przeprowadzonego badania dostępności wydarzeń organizowanych przez polskie uczelnie. W pracy zawarto ponadto praktyczne wskazówki dla ich organizatorów, zainteresowanych spełnieniem wymagań dostępności.
Dynamics of Odonata in an Agroecosystem: Effects of Paddy Cultivation Phases on the Diversity of Dragonflies and Damselflies
Authors: Priyadarshana P.H.M.G.C.  , Ranaweera S.R.D.  , Shafa S.M.R.  , Gunawardena M.P.  
Published: February 2024

Wetlands represent a major part of biodiversity and provide habitat to many species which cannot succeed in other ecosystems. Man-made wetlands like Paddy fields represent a greater percentage of wetland ecosystems in Sri Lanka. However, there are only a few studies that observed the Odonata diversity in man-made wetland ecosystems in Sri Lanka. Therefore, this study was conducted to observe the effect of cultivation phases of a paddy-field ecosystem on the diversity of Odonata. The paddy culture period chosen for the study was started in June 2022 and ended in September 2022 and the study covered the Seeding, Tillering, Booting, Flowering, and Harvesting phases. Fixed-radius point count method was used for the data collection purpose and ten circular plots of 5m radius were laid maintaining a 50 m distance between two plots in the study area which had a total area of 785m2. At all five successive stages of the cultivation cycle, the number of Odonata species and their abundance were recorded once a week in each plot. Data was recorded each day from 8.00 am to 10.00 am and from 3.00 pm to 5.00 pm. Odonata diversity was calculated separately at each of the stages of the paddy cultivation cycle using Simpson‘s index (D) and Shannon- wiener index (H‘). According to results, 592 individuals were recorded belonging to 14 species of Odonata in 02 families. Among the total recorded species, 64% of species belonged to the family Libellulidae. Sri Lankan Orange-faced Sprite (Pseudagrion rubriceps ceylonicum) was the only endemic Odonata species that were recorded during the study. The overall H‘ and D diversity indexes were 1.71 and 0.75, respectively. Values of H‘ and D diversity indexes for these five stages (Seeding, Tillering, Booting, Flowering, and Harvesting) were 1.36 & 0.65, 1.59 & 0.72, 1.72 & 0.76, 1.81 & 0.79 and 1.59 & 0.78, respectively. The study revealed that among the index values of each cultivation phase, the flowering stage had the highest diversity, while the seeding phase showed the lowest diversity. Therefore, it is evident that the transformation of land use/habitat in different stages plays a major role in the diversity of Odonata. and this study can be used to depict the impacts on biodiversity due to the degradation of wetlands.
Keywords: Odonata, Paddy cultivation phases, Biodiversity, Man-made wetland
Life Cycle Assessment of Conventionally and Organically Grown Pineapple in Gampaha District
Authors: Gunawardena M.A.  , Lokupitiya E.Y.K  
Published: February 2024

Pineapple is one of the major commercial fruits grown in Gampaha and Kurunegala districts of Sri Lanka. Most cultivations are under conventional practices which generate significant environmental impacts while there are few organic cultivations (~1%). There is lack of published on the environmental impacts related to cultivation of pineapple in Sri Lanka. This study therefore aimed to quantify and compare environmental impacts of conventionally and organically grown pineapple in Gampaha District. Environmental impacts were compared using Life Cycle Assessment (LCA) tool which evaluates the potential environmental impacts throughout the life cycle of a product or a process. According to ISO 14040:2006 and ISO 14044:2006 guidelines, LCA methodology has four main phases such as goal and scope definition, life cycle inventory analysis (LCI), life cycle impact assessment (LCIA), and life cycle interpretation. The system boundary for the study was from cradle to farm gate. All the environmental impacts were estimated for a functional unit of one tonne of pineapple. Primary data for the LCA was gathered using a pre-tested structured questionnaire conducted among twenty conventional- and six organic farms. Input and output inventories were prepared during LCI phase. Under LCIA phase, impact categories such as global warming potential (GWP), eutrophication, human toxicity, terrestrial ecotoxicity, and freshwater ecotoxicity were considered. Results indicated that conventional cultivation system has significantly higher impacts compared to the organic cultivation system. Global warming potential of conventionally cultivated one tonne of pineapple was 182.23 kg CO2 eq. It was 26.72 kg CO2 eq for organic cultivation indicating 7 times lower impact. Eutrophication potential was 6.63 kg PO43- eq for conventional cultivation while that for organic cultivation was 0.81 kg PO43- eq (8 times lower). Pesticide use has resulted in 2,279.12 kg 1,4 DB eq of human toxicity, 18,331.71 kg 1,4 DB eq of freshwater ecotoxicity and 1,624,494.37 kg 1,4 DB eq terrestrial ecotoxicity for conventional cultivation while organic cultivations have resulted in no toxicity. The results highlight significant contribution of synthetic fertilizers and pesticides towards all five impact categories of the LCA. The results could provide implications for promoting organic cultivation in order to reduce the impacts on the environment in the long run.
Keywords: Life cycle assessment, Pineapple, Conventional cultivation, Organic cultivation, Environmental impacts
Comparative Study of Bisphenol-A and its Analogue Bisphenol-S on Growth and Condition Factor of Juvenile Zebrafish (Danio rerio)
Authors: Dulanthi M.L.Y.  , Rajapaksa R.P.G.K.  
Published: February 2024

Bisphenol-A is a synthetic estrogen highly used in the production of polycarbonate plastics and epoxy resins in plastic industry world-wide. Bisphenol-A presents as a ubiquitous environmental contaminant in all ecosystems. Bisphenol-A is an endocrine disruptor which affects the growth, development and physiology of living organisms. Therefore, bisphenol-S has been introduced as a safe alternative to bisphenol-A and it has become the widely used bisphenol-A substitute. Bisphenol-S has also been identified as an endocrine disruptor and emerging environmental contaminant. Therefore the safety of bisphenol-S substitution has become questionable. Thus, this study was carried out to comparatively assess the impacts of bisphenol-A and bisphenol-S exposure on growth and condition factor of zebrafish (Danio rerio). After 7-days acclimatization period, twenty juvenile zebrafish of 67 dpf (days post fertilization) of age were treated 35 days with 10 μg/L and 100 μg/L of bisphenol-A, bisphenol-S and with treatment control in triplicate tanks. Mean body length, weight, specific growth rate and condition factor of fish were evaluated. Mean body weight increment of zebrafish under 100 μg/L of bisphenol-S and bisphenol-A were significantly different from the treatment control (p<0.05, One way ANOVA, Tukeys pairwise Comparison). The mean body length increment and specific growth rate were not significant under both concentrations of bisphenol-S and bisphenol-A with treatment control (p>0.05). However, the condition factor of fish under both concentrations of bisphenols were significantly less than control (p<0.05). The condition factor of fish under comparable concentrations of bisphenol-S and bisphenol-A were not statistically significant. Therefore, it can be concluded that exposure to environmental concentrations of both types of bisphenols could affect the wellbeing of juvenile zebrafish. Based on the findings, bisphenol-S cannot be recommended as a safe substitution to bisphenol-A. Yet, more comprehensive studies are recommended to evaluate relative effect of bisphenol-S on freshwater ecosystem health.
Keywords: Body length, Body weight, Condition factor, Bisphenol-A, Bisphenol-S, Zebrafish, (Danio rerio)