bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clogging nets-Didemnum vexillum (Tunicata: Ascidiacea) is in action in the eastern Mediterranean
Authors: Çinar Melih Ertan , Özgül Aytaç 
Published: November 2023

Abstract
Didemnum vexillum is an aggressive, rapidly growing colonial ascidian and regarded as a global alien invasive species in temperate waters. It has recently become established in the western Mediterranean and the vectors of its introduction were assumed to be shipping or oyster trade. A dense settlement of it was encountered on nets of the bluefin tuna (Thunnus thynnus) cages placed at 60–65 m depths off the İzmir Peninsula (eastern Aegean Sea, eastern Mediterranean) in December 2022. It had considerably clogged net's eye openings, hindering water circulations inside cages. It had a vertical distributional pattern on 35 m long-nets, occurring solely on depths from surface down to 15 m, around where a summer thermocline develops. It has entirely replaced the native black mussel Mytilus galloprovincialis on nets. This colonial ascidian changed the routine cleaning procedure of nets in the farming. Three possible ways of its introduction to the eastern Mediterranean were proposed, but the most reasonable one is its secondary transfer via nets or ships from Malta. Mechanisms of its invasion biology and behaviour should be studied and monitored in the region.
A study on the development and trend of COLREGs – A broader perspective
Authors: Dong Wenhai , Li Jie , Tu Xinghua 
Published: November 2023

AbstractWith the rapid development of the maritime industry and the emergence of unmanned ships, it is necessary to continuously review the International Regulations for Preventing Collisions at Sea (1972, COLREGs). This paper provides an overview of the developing history of the COLREGs and summarises the interpretations made by the International Maritime Organization official and academic scholars. Additionally, the paper discusses the application of the COLREGs in collision avoidance geometry and autonomous collision avoidance systems. Furthermore, the necessity and key points of revisions to adapt to industry advancements are discussed, along with an analysis of the main challenges faced. Finally, in light of the continuous progress and implementation of the outcome of the Regulatory Scoping Exercise for the Use of Maritime Autonomous Surface Ships (MASS), the paper points out that achieving consistency between manned and unmanned vessels, as well as developing COLREGs-based autonomous collision avoidance systems for more complex scenarios, is expected to be a significant trend in the future.
120 GHz microstrip power amplifier MMICs in a commercial GaAs process
Authors: Mahon Simon J. , McCulloch MacCrae G. , Mihaljevic Jakov , Gorman Melissa C. , Parker Anthony E. , Heimlich Michael C. 
Published: November 2023

AbstractSingle-ended and balanced 90–120 GHz microstrip power amplifier MMICs have been designed for cost-sensitive 5G and 6G backhaul in a commercial 6-inch, 0.1-µm GaAs process. At 108 GHz, measured output power is 20.4 and 22.5 dBm, respectively. At 120 GHz, measured output is 12.6 and 17.4 dBm, respectively. This is the highest reported for GaAs, among the highest reported to date for microstrip MMIC amplifiers at these frequencies and competitive with more expensive InP and GaN processes. Measurement is compared with simulation.
Geophysical and Geochemical Constraints on Magma Storage Depths Along the Cascade Arc: Knowns and Unknowns
Authors: Wieser Penny E. , Kent Adam J. R. , Till Christy B. , Abers Geoff A. 
Published: November 2023

AbstractThe iconic volcanoes of the Cascade arc stretch from Lassen Volcanic Center in northern California, through Oregon and Washington, to the Garibaldi Volcanic Belt in British Columbia. Recent studies have reviewed differences in the distribution and eruptive volumes of vents, as well as variations in geochemical compositions and heat flux along strike (amongst other characteristics). We investigate whether these along‐arc trends manifest as variations in magma storage conditions. We compile available constraints on magma storage depths from InSAR, geodetics, seismic inversions, and magnetotellurics for each major edifice and compare these to melt inclusion saturation pressures, pressures calculated using mineral‐only barometers, and constraints from experimental petrology. The availability of magma storage depth estimates varies greatly along the arc, with abundant geochemical and geophysical data available for some systems (e.g., Lassen Volcanic Center, Mount St. Helens) and very limited data available for other volcanoes, including many which are classified as “very high threat” by the USGS (e.g., Glacier Peak, Mount Baker, Mount Hood, Three Sisters). Acknowledging the limitations of data availability and the large uncertainties associated with certain methods, available data are indicative of magma storage within the upper 15 km of the crust (∼2 ± 2 kbar) beneath the main edifices. These findings are consistent with previous work recognizing barometric estimates cluster within the upper crust in many arcs worldwide. There are no clear offsets in magma storage between arc segments that are in extension, transtension or compression, although substantially more petrological work is needed for fine scale evaluation of storage pressures.
Observed and Projected Changes in North Atlantic Seasonal Temperature Reduction and Their Drivers
Authors: Grist Jeremy P. , Josey Simon A. , Sinha Bablu 
Published: November 2023

AbstractThe autumn‐winter seasonal temperature reduction (STR) of the surface North Atlantic Ocean is investigated with control and climate change simulations of a coupled model and an observation‐based sea surface temperature (SST) data set. In the climate change simulation, an increase in the magnitude of the STR is found over much of the North Atlantic, and this change is particularly marked in sea‐ice affected regions and the subpolar gyre. Similar results for the mid‐high latitude North Atlantic are obtained in the observational analysis. In particular, both the observation and climate model based results show that the STR has increased in magnitude by up to 0.3°C per decade in the subpolar gyre over the period 1951–2020. Drivers for the stronger STR are explored with a focus on potential contributions from increases in either ocean heat loss or the sensitivity of SST to heat loss. Over a large part of the mid‐high latitude North Atlantic surface heat loss is found to have weakened in recent decades and is therefore not responsible for the stronger STR (exceptions to this are the near‐coastal areas where sea‐ice loss is important). In contrast, analysis of daily sensible and latent heat flux data reveals that the sensitivity of SST to heat loss has increased indicating that this term has played a major role in the stronger STR. Areas of greater SST sensitivity (and greater STR) are associated with increased surface stratification brought about predominantly by warming of the northern ocean regions.
A New Approach to Soil Initialization for Studying Subseasonal Land‐Atmosphere Interactions
Authors: Jiang Yelin , Wang Guiling 
Published: November 2023

AbstractNumerical experiments on sensitivity to land surface initializations are frequently conducted to investigate the predictability and uncertainties of hydrometeorological extremes. However, the conventional approaches to soil initialization often assume synchronized extremes over the target region, creating initial conditions that violate the intrinsic spatial pattern of hydrometeorological variability. Here we propose a “Slope” approach to accommodate unsynchronized anomalies, which creates initial conditions of a variable (soil temperature or soil moisture) across a large domain based on the slopes of linear regression between the variable averaged over a small target region and at each grid point in the surrounding regions. Within the target region, the “Slope” approach produces spatial patterns and temporal evolutions of hydrometeorological responses similar to the conventional approach, but generates stronger signals probably due to the nonlocal impact (excluded from the conventional approach). In the surrounding regions, the hydrometeorological responses in the “Slope” approach are consistent with the spatiotemporal variability of the model climate. Slope‐based experiments targeting different adjacent regions produce similar results, suggesting that one ensemble of experiments targeting one region may be sufficient to represent the responses from multiple ensembles each targeting a different region and thus providing the basis for increasing the computational efficiency of some land‐atmosphere interaction studies. While South America is used to demonstrate the concept in this study, the new approach offers the most advantages in regions with spatially unsynchronized or even anti‐phased hydrometeorological extremes.
Impacts of Channel‐Spanning Log Jams on Hyporheic Flow
Authors: Huang S. H. , Yang J. Q. 
Published: November 2023

AbstractIn‐stream wood structures, such as single logs, river steps, and debris dams, are known to drive hyporheic flow, defined as the flow that goes into the subsurface region and then back to the free‐flowing surface water. The hyporheic flow plays an important role in regulating water quality and biogeochemical cycles in rivers. Here, we investigated the impact of a channel‐spanning porous log jam, representing piles of wood logs, on hyporheic flow through a combination of direct visualization and theories. Specifically, we developed a method using refractive index‐matched sediment to directly visualize the hyporheic flow around and below a porous log jam, formed by piles of cylindrical rods, in a laboratory flume. We tracked the velocity of a fluorescent dye moving through the transparent sediment underneath the log jam. In addition, we measured the water surface profile and the spatially varying flow velocity near the log jam. Our results show that the normalized log jam‐induced hyporheic flux remained smaller than 10% at Froude numbers () below 0.06 and increased by a factor of five with increasing at . We combined the mass and momentum conservation equations of surface flow with Darcy's equation to explain the dependency of the log jam‐induced hyporheic flux on . Further, we observed that at , the water surface dropped noticeably and the turbulent kinetic energy increased immediately on the downstream side of the log jam. These findings will facilitate future quantification of hyporheic flow caused by channel‐spanning porous log jams.
Estimating the impact of transmitted and non-transmitted psychiatric and neurodevelopmental polygenic scores on youth emotional problems
Authors: Shakeshaft Amy , Martin Joanna , Dennison Charlotte A. , Riglin Lucy , Lewis Cathryn M. , O’Donovan Michael C. , Thapar Anita 
Published: November 2023

AbstractAnxiety and depression (emotional disorders) are familial and heritable, especially when onset is early. However, other cross-generational studies suggest transmission of youth emotional problems is explained by mainly environmental risks. We set out to test the contribution of parental non-transmitted genetic liability, as indexed by psychiatric/neurodevelopmental common polygenic liability, to youth emotional problems using a UK population-based cohort: the Millennium Cohort Study. European (N = 6328) and South Asian (N = 814) ancestries were included, as well as a subset with genomic data from both parents (European: N = 2809; South Asian: N = 254). We examined the association of transmitted (PGST) and non-transmitted polygenic scores (PGSNT) for anxiety, depression, bipolar disorder and neurodevelopmental disorders (attention-deficit/hyperactivity disorder [ADHD], autism spectrum disorder [ASD], schizophrenia) with youth emotional disorder and symptom scores, measured using the parent- and self-reported Strengths and Difficulties Questionnaire emotional subscale at 6 timepoints between ages 3–17 years. In the European sample, PGST for anxiety and depression, but not bipolar disorder, were associated with emotional disorder and symptom scores across all ages, except age 3, with strongest association in adolescence. ADHD and ASD PGST also showed association across ages 11–17 years. In the South Asian sample, evidence for associations between all PGST and outcome measures were weaker. There was weak evidence of association between PGSNT for anxiety and depression and age 17 symptom scores in the South Asian sample, but not in the European sample for any outcome. Overall, PGST for depression, anxiety, ADHD and ASD contributed to youth emotional problems, with stronger associations in adolescence. There was limited support for non-transmitted genetic effects: these findings do not support the hypothesis that parental polygenic psychiatric/neurodevelopmental liability confer risk to offspring emotional problems through non-transmitted rearing/nurture effects.
Vasotocin receptor gene genotypes moderate the relationship between cortical thickness and sensory processing
Authors: Lee Seonkyoung , Cheong Yongjeon , Ryu Yeseul , Kosaka Hirotaka , Jung Minyoung 
Published: November 2023

AbstractSensory processing is the process by which the central nervous system gathers, interprets, and regulates sensory stimuli in response to environmental cues. However, our understanding of the genetic factors and neuroanatomical correlations that influence sensory processing is limited. The vasotocin system modulates sensory input responsiveness, making it a potential candidate for further investigation. Additionally, human neuroimaging studies have demonstrated that the ability to modulate sensory stimuli is related to neuroanatomical features such as cortical thickness. Therefore, this study aimed to examine the relationship between functional polymorphisms in vasotocin receptor (VTR) genes, sensory profiles, and neuroanatomical correlations. We used structural magnetic resonance imaging (MRI) and the Adolescent/Adult Sensory Profile (AASP) questionnaire in 98 healthy adult participants to assess sensory processing and identified seven single nucleotide polymorphisms. We found that A-allele carriers of rs1042615 in VTR had higher scores for “sensory sensitivity” and “sensation avoiding”. Moreover, higher scores for three AASP subscales were associated with decreased cortical thickness in various regions, including the right precentral, paracentral, and fusiform gyri, as well as bilateral inferior temporal gyri. This study sheds light on the potential role of genetic variations in the VTR in modulating sensory processing and correlation with cortical thickness which has future implications for better understanding sensory abnormalities in neurodevelopmental disorders.
Unifying the design space and optimizing linear and nonlinear truss metamaterials by generative modeling
Authors: Zheng Li , Karapiperis Konstantinos , Kumar Siddhant , Kochmann Dennis M. 
Published: November 2023

AbstractThe rise of machine learning has fueled the discovery of new materials and, especially, metamaterials—truss lattices being their most prominent class. While their tailorable properties have been explored extensively, the design of truss-based metamaterials has remained highly limited and often heuristic, due to the vast, discrete design space and the lack of a comprehensive parameterization. We here present a graph-based deep learning generative framework, which combines a variational autoencoder and a property predictor, to construct a reduced, continuous latent representation covering an enormous range of trusses. This unified latent space allows for the fast generation of new designs through simple operations (e.g., traversing the latent space or interpolating between structures). We further demonstrate an optimization framework for the inverse design of trusses with customized mechanical properties in both the linear and nonlinear regimes, including designs exhibiting exceptionally stiff, auxetic, pentamode-like, and tailored nonlinear behaviors. This generative model can predict manufacturable (and counter-intuitive) designs with extreme target properties beyond the training domain.
Isolation may select for earlier and higher peak viral load but shorter duration in SARS-CoV-2 evolution
Authors: Sunagawa Junya , Park Hyeongki , Kim Kwang Su , Komorizono Ryo , Choi Sooyoun , Ramirez Torres Lucia , Woo Joohyeon , Jeong Yong Dam , Hart William S. , Thompson Robin N. , Aihara Kazuyuki , Iwami Shingo , Yamaguchi Ryo 
Published: November 2023

AbstractDuring the COVID-19 pandemic, human behavior change as a result of nonpharmaceutical interventions such as isolation may have induced directional selection for viral evolution. By combining previously published empirical clinical data analysis and multi-level mathematical modeling, we find that the SARS-CoV-2 variants selected for as the virus evolved from the pre-Alpha to the Delta variant had earlier and higher peak in viral load dynamics but a shorter duration of infection. Selection for increased transmissibility shapes the viral load dynamics, and the isolation measure is likely to be a driver of these evolutionary transitions. In addition, we show that a decreased incubation period and an increased proportion of asymptomatic infection are also positively selected for as SARS-CoV-2 mutated to adapt to human behavior (i.e., Omicron variants). The quantitative information and predictions we present here can guide future responses in the potential arms race between pandemic interventions and viral evolution.
Woven organic crystals
Authors: Lan Linfeng , Li Liang , Qi Jianqun , Pan Xiuhong , Di Qi , Naumov Panče , Zhang Hongyu 
Published: November 2023

AbstractWoven architectures are prepared by physical entanglement of fibrous components to expand one-dimensional material into two-dimensional sheets with enhanced strength and resilience to wear. Here, we capitalize on the elastic properties of long organic crystals with a high aspect ratio to prepare an array of centimeter-size woven network structures. While being robust to mechanical impact, the woven patches are also elastic due to effective stress dissipation by the elasticity of the individual warp and weft crystals. The thermal stability of component crystals translates into favorable thermoelastic properties of the porous woven structures, where the network remains elastic over a range of 300 K. By providing means for physical entanglement of organic crystals, the weaving circumvents the natural limitation of the small size of slender organic crystals that is determined by their natural growth, thereby expanding the prospects for applications of organic crystals from one-dimensional entities to expandable, two-dimensional robust structures.
Heterogeneous encoding of temporal stimuli in the cerebellar cortex
Authors: De Zeeuw Chris. I. , Koppen Julius , Bregman George. G. , Runge Marit , Narain Devika 
Published: November 2023

AbstractLocal feedforward and recurrent connectivity are rife in the frontal areas of the cerebral cortex, which gives rise to rich heterogeneous dynamics observed in such areas. Recently, similar local connectivity motifs have been discovered among Purkinje and molecular layer interneurons of the cerebellar cortex, however, task-related activity in these neurons has often been associated with relatively simple facilitation and suppression dynamics. Here, we show that the rodent cerebellar cortex supports heterogeneity in task-related neuronal activity at a scale similar to the cerebral cortex. We provide a computational model that inculcates recent anatomical insights into local microcircuit motifs to show the putative basis for such heterogeneity. We also use cell-type specific chronic viral lesions to establish the involvement of cerebellar lobules in associative learning behaviors. Functional heterogeneity in neuronal profiles may not merely be the remit of the associative cerebral cortex, similar principles may be at play in subcortical areas, even those with seemingly crystalline and homogenous cytoarchitectures like the cerebellum.
The structure of the teleost Immunoglobulin M core provides insights on polymeric antibody evolution, assembly, and function
Authors: Lyu Mengfan , Malyutin Andrey G. , Stadtmueller Beth M. 
Published: November 2023

AbstractPolymeric (p) immunoglobulins (Igs) serve broad functions during vertebrate immune responses. Typically, pIgs contain between two and six Ig monomers, each with two antigen binding fragments and one fragment crystallization (Fc). In addition, many pIgs assemble with a joining-chain (JC); however, the number of monomers and potential to include JC vary with species and heavy chain class. Here, we report the cryo-electron microscopy structure of IgM from a teleost (t) species, which does not encode JC. The structure reveals four tIgM Fcs linked through eight C-terminal tailpieces (Tps), which adopt a single β-sandwich-like domain (Tp assembly) located between two Fcs. Specifically, two of eight heavy chains fold uniquely, resulting in a structure distinct from mammalian IgM, which typically contains five IgM monomers, one JC and a centrally-located Tp assembly. Together with mutational analysis, structural data indicate that pIgs have evolved a range of assembly mechanisms and structures, each likely to support unique antibody effector functions.
Distinct value computations support rapid sequential decisions
Authors: Mah Andrew , Schiereck Shannon S. , Bossio Veronica , Constantinople Christine M. 
Published: November 2023

AbstractThe value of the environment determines animals’ motivational states and sets expectations for error-based learning1–3. How are values computed? Reinforcement learning systems can store or cache values of states or actions that are learned from experience, or they can compute values using a model of the environment to simulate possible futures3. These value computations have distinct trade-offs, and a central question is how neural systems decide which computations to use or whether/how to combine them4–8. Here we show that rats use distinct value computations for sequential decisions within single trials. We used high-throughput training to collect statistically powerful datasets from 291 rats performing a temporal wagering task with hidden reward states. Rats adjusted how quickly they initiated trials and how long they waited for rewards across states, balancing effort and time costs against expected rewards. Statistical modeling revealed that animals computed the value of the environment differently when initiating trials versus when deciding how long to wait for rewards, even though these decisions were only seconds apart. Moreover, value estimates interacted via a dynamic learning rate. Our results reveal how distinct value computations interact on rapid timescales, and demonstrate the power of using high-throughput training to understand rich, cognitive behaviors.