bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of Patients Admitted with and without COVID-19 and Gastrointestinal Bleeding During the Early Pandemic: A Retrospective Review
Authors: Jones-Pauley Michelle , Waghela Rajdeepsingh , Ordonez Adriana , Xu Jiaqiong , Mathur Neha 
Published: November 2023

Abstract

During the first wave of the pandemic (March 2020-July 2020), it was postulated that there may be an increased risk of gastrointestinal bleeding (GIB) due to COVID-related inflammatory effects on the intestinal mucosa, as well as microthrombi from the hypercoagulable state induced by COVID. We performed a retrospective, multi-center, 1:2 case-control study to review 122 COVID-positive patients and 269 patients without COVID. There were no significant differences between the COVID and non-COVID patients for increased risk of GI bleeding. We concluded that despite the altered pathophysiology of the culprit lesions due to COVID infection, the same standard medical and endoscopic management strategies should be employed.
Clinical characteristics and half-year outcomes of 53 children with severe adenovirus pneumonia complicated with encephalitis or encephalopathy
Authors: Zeng Lingjian , Wei Jianhua , Liu Enmei , Li Qubei , Zang Na 
Published: November 2023

Abstract
The clinical characteristics and prognosis of children with human adenovirus pneumonia complicated with encephalitis or encephalopathy remain unclear. We analyzed clinical datas of 53 children who were admitted to the Respiratory Department of Children's Hospital of Chongqing Medical University in 2019 with severe adenovirus pneumonia and complicated with viral encephalitis or encephalopathy retrospectively, and 78 cases diagnosed with severe adenovirus pneumonia but without encephalitis or encephalopathy were selected as controls. Among the 53 children, 32 (60.4%) were males with a median age of 18.0(7.5-37.0) months. All of them had fever and cough, and the median fever duration was 12.0(9.5-15.0) days, 90.6%(48/53) had listlessness, 62.3%(33/53) had dysphoria, 47.2%(25/53) had hypersomnia, 13.2%(7/53) had seizure, and 30.2%(16/53) had positive signs in nervous system physical examination. The median leukocyte count of children with encephalitis or encephalopathy was 7.39 (3.53-10.73) *10^9/L, the median procalcitonin was 1.885(0.390-4.555)ng/ml, and the median lactate dehydrogenase was 980.50 (516.40-1938.00) U/L, these were significant differences compared with the control group (P values were 0.011, 0.001, 0.000), but there was no difference in nasopharyngeal adenovirus load. Children with encephalitis or encephalopathy are more likely to be complicated with leukopenia, hypoproteinemia, liver function impairment, coagulopathy, anemia, pleural effusion, abdominal effusion, hemophagocytic lymphohistiocytosis. 75.47% (40/53) of the children needed mechanical ventilation, and the rate of tracheal intubation and mechanical ventilation time were significantly increased compared with the control group (P values were 0.039, 0.000). The rates of gamma globulin, albumin and blood transfusion were 92.45% (49/53), 52.83% (28/53) and 26.42% (14/53), which were significantly higher than those in the control group (P values were 0.004, 0.000, 0.028). At the follow-up of half a year later, 35.85% (19/53) showed obliterative bronchiolitis, which was significantly higher than 11.54% (9/78) in the control group ( c2=11.098, P=0.001), and there was no obvious sequelae in the nervous system.
Conclusion It is necessary to be aware of the possibility of encephalitis/encephalopathy in children with severe adenovirus pneumonia when the consciousness state changes such as listlessness. The clinical manifestations of these children are severe and the prognosis of the nervous system is not bad, but the incidence of bronchiolitis obliterans is high in the later stage.
An Empirical Study on the Effect of Sports Vision Training on Primary School Students’ Motor Coordination
Authors: Zhang Shiping , Hu Liangping , Luo Bingquan 
Published: November 2023

Abstract

Background Motor coordination plays a crucial role in the overall physical development of primary school students. However, targeted training for motor coordination skills in this age group is often lacking in physical education programs. This study aims to investigate the impact of sports vision training on primary school students' motor coordination. Methods The study involved primary school students at three different grade levels. Sports vision training was implemented in the experimental group during their physical education classes, while the control group received standard physical education instruction. Various aspects of sports vision, including static visual acuity, dynamic visual acuity, visual focus, visual tracking, peripheral vision, image fusion flexibility, depth perception, visualisation, hand (foot) eye coordination, instant vision, and visual concentration, were assessed before and after the training period. Motor coordination skills, spatial orientation ability, balance ability, and cognitive ability were also measured. Results The results indicate that scientific sports vision training methods effectively improved key motor visual abilities in primary school students. These improvements were closely linked to body movement-related nerves. Specifically, students showed enhancements in static and dynamic visual acuity, visual focus, peripheral vision, hand (foot) eye coordination, and other sports vision skills. These improvements positively impacted their spatial orientation ability, balance ability, and cognitive ability, contributing to the development of motor coordination. Conclusions Sports vision training can be an effective method to enhance primary school students' motor coordination. By improving their visual skills and coordination, students can better navigate physical activities and develop a strong foundation for their overall physical development. This study highlights the importance of integrating sports vision training into primary school physical education programs to promote healthier and more coordinated young athletes.
Potential analysis of residential composite energy storage system application based on double-layer optimization model
Authors: Zhao Xueyuan , Ying Xiaoyu , Gao Weijun , Qian Fanyue , Tan Yang , Xie Jing 
Published: November 2023

Abstract
Along with the further integration of demand management and renewable energy technology, it is the key to make optimal use of energy storage facilities and coordinate operation with other facilities. On the basis of the present study, the author takes into account the current situation of the power storage equipment. Based on the measured data for one year, four cases are designed for the compound energy storage system. In this paper, a two-tiered optimization model is proposed, which is used to optimizing the capacity of the power storage facilities and yearly production of the system. Furthermore, the paper makes a comparative analysis on the performance of the four cases from energy, environmental and economic aspects. It is concluded that this kind of energy-storing equipment can enhance the economy and environment of residence energy system. Thermal energy storage system has the shortest payback period of 7.84 years, but the CO2 emissions are the least. Coupled with future price volatility and carbon tax, the hybrid electric energy storage system has a good development potential. However, the current cost of investment is very high, and it will not be possible to recover it in 10 years. Finally, it is recommended that the cost of equipment should be reduced in combination with subsidies and incentives to promote further. The research results not only fill the blank of the study area, at the same time, it provides some suggestions for further development of research and industry on user-side energy storage.
Atmospheric destabilization dominates Arctic Ocean winter surface wind intensification
Authors: Zapponini Martina , Goessling Helge 
Published: November 2023

Abstract

The surface-amplified winter warming over the Arctic Ocean, simulated by CMIP6 climate models and emerging from ERA5 reanalysis, is accompanied by a pronounced intensification of near-surface winds. Here, the influences of sea-ice decline, wind changes aloft, and atmospheric stability are revisited. Spatial trend patterns suggest that near-surface wind intensification over the inner Arctic Ocean in winter is largely driven by an increasing downward momentum transfer due to a weakening atmospheric stratification. In contrast, a near-surface wind intensification in summer appears to be largely driven by accelerating winds aloft, amplified in a high-emission future by decreasing surface roughness due to sea-ice decline. In both seasons, differences in near-surface wind-speed trends are closely linked to atmospheric stability trends. Models suggest that by 2100 the lower troposphere may become as unstable in winter as in summer, implying a fundamental regime shift of the Arctic winter boundary layer, with major potential repercussions on sea ice, ocean waves, marine navigation, and coastal erosion.
Comparison of Millimeter Wave Power Amplifiers with Different Power Combining Techniques
Authors: Bagger Reza , Sjöland Henrik 
Published: November 2023

Abstract
Four-millimetre wave power amplifiers, three-stage differential cascode with inductively coupled impedance transformers, were designed and fabricated in a 130 nm SiGe HBT BiCMOS process with fMAX = 330 GHz. The PAs, where the signal splitting/combining, number of differential pairs and transistor size in the final stage differ, are used in power/efficiency benchmarking. Balun as output impedance transformer was used in two of PAs with different transistor sizes in their third stage, 120 µm respective 160 µm. The power combiners in two other PA embodiments were realized by Parallel Combining Transformer, PCT, and Series Combining Transformer, SCT. The PAs with balun combiner achieve a PSAT of 19.3 dBm with 10.5% third stage PAE at 8.5 dB backoff from PSAT, PAE3rd BO. For the PA with SCT combiner, PSAT was 18.3 dBm with 7% PAE3rd BO, and the PA using PCT achieved a PSAT of 18 dBm and 6.5% PAE3rd BO, measured at 39 GHz. The fractional bandwidths exceeded 36% for balun and SCT and 32% for PCT, respectively. The implemented SCT and PCT with their lower input impedance show lower voltage swing at collector of final stage for equivalent output power level compared with one-way combiner (balun). Also the PAs with PCT and SCT show a lower sensitivity to load impedance variations.
Determinants of preterm delivery among mothers who gave birth in hospitals of Wolaita zone, southern Ethiopia, 2023: Unmatched case-control study
Authors: Tilahun Cherinet , Getie Asmare , Tadesse Hiwot , Geta Temesgen , Ashiko Adisu 
Published: November 2023

Abstract

Background: Preterm delivery refers to childbirth that occurs before 37 full weeks’ gestation. Globally, around 13.4 million babies are born preterm annually, a million died due to its complications. Identifying its determinants is mandatory to decrease preterm birth and thereby neonatal deaths. Therefore, this study aimed to identify the determinants of preterm delivery among mothers who gave birth in hospitals in the Wolaita zone, southern Ethiopia.
Methods: An Institutional-based unmatched case-control study design was conducted from March 29 to May 20, 2023, in the Wolaita zone, southern Ethiopia. Cases were women who gave birth after 28 weeks and before 37 completed weeks, and controls were women who gave birth at and after 37 and before 42 weeks of gestation from the first day of the last normal menstrual period. A consecutive sampling method was used. Data were collected by a structured interviewer-administered questionnaire. Data were coded and entered into Epi data 3.1 and analyzed by using SPSS version 25. Variables that had a P-value < 0.25 in the bivariate logistic regression analysis were entered into a multivariable logistic regression model. Finally, p-value < 0.05 was used to claim statistical significance.
Result: From a total of 405 eligible participants, 399 respondents (133 cases and 266 controls) participated in this study with a response rate of 98.52%. The result of the multivariable analysis shows that mothers who resided in rural areas [AOR=2.777:95% CI (1.507-5.118)], not receiving support from their partner [AOR=2.368:95% CI (1.243-4.514)], less than four antenatal care visits [AOR=4.520:95%CI (2.384-8.569)], developed pregnancy-induced hypertension [AOR=5.248:95%CI (2.270-12.135)] and exposed for intimate partner violence [AOR=2.945:95%CI (1.105-7.848)], had statistically significant association with experiencing preterm delivery.
Conclusion and Recommendation: Most of the determinants for preterm delivery have been proven modifiable. Thus, designing new strategies, providing policy for partner support during pregnancy and Health care providers should give due attention to mothers with pregnancy-induced hypertension and exposure to intimate partner violence and increase the awareness of antenatal care follow-up and support during pregnancy to reduce preterm delivery.
Mesenchymal stem cells derived exosomes ameliorate D-galN/LPS induced acute liver injury via PTEN-mediated macrophage polarization
Authors: Zhang Zhi , Fu Yu , Wei Shuyi , Liang Liwei , Li Ting , Feng Lei , Cai Lei , Fu Shunjun , Li Yang , Li Shao , Pan Mingxin , He Guolin 
Published: November 2023

Abstract
Background: It is widely acknowledged that Mesenchymal Stem Cells (MSCs) exert their effects through paracrine mechanisms by releasing bioactive components, such as exosomes, while previous studies have confirmed the critical role of macrophage polarization in acute liver injury, the impact of exosome-mediated liver repair on macrophage polarization requires further clarification.
Methods: Human placental mesenchymal stem cell-derived exosomes (hPMSC-Exo) were intravenously administered to the mice 2 hours before exposure to LPS/GalN. The effects of hPMSC-Exo were evaluated using serum biochemical analysis, TUNEL assay, and H&E staining. In order to elucidate the mechanisms underlying acute liver injury therapy, the expression levels of relevant genes were evaluated using qPCR and WB analysis, respectively. The exosome transfected miR-26-5p were used for further determine the mTOR signaling in hPMSC-Exo based threapy.
Results: hPMSC-Exo alleviated liver inflammation and promoted liver repair in a mouse model of D-galN/LPS-induced DILI (drug-induced liver injury). Subsequent investigations revealed that hPMSC-Exo induced the polarization of M1 macrophages towards an M2 phenotype, both in vivo and in vitro. Bioinformatics analysis identified miR-26-5p as a potential mediator of macrophage polarization and PTEN as its downstream target. Attenuation of macrophage polarization modulation was observed when miR-26-5p levels were reduced in hPMSC-Exo. Similarly, knockdown of PTEN also demonstrated hepatoprotective efficacy and reduced inflammation levels in a mouse model of DILI.
Conclusion: Our findings suggest the involvement of the PTEN/mTOR/TGF-β1 signaling pathway in regulating macrophage activation through hPMSC exosomal miR-26-5p, highlighting its therapeutic potential in the treatment of liver injury.
Surgical Outcomes of Adults with Spinal Tuberculosis from 1992 to 2019: A Single-Center Study
Authors: Furukawa Mitsuru , Fujiyoshi Kanehiro , Yanai Yoshihide , Kato Takashi , Kobayashi Yoshiomi , Konomi Tsunehiko , Yato Yoshiyuki 
Published: November 2023

Abstract
Objectives: This study aims to investigate the postoperative fusion rate and risk factors for kyphosis progression in adults affected with spinal tuberculosis.
Methods: Overall, 134 patients with spinal tuberculosis from the thoracic to lumbar spine from 1992 to 2021 were included in this study. The patients were divided into Group A, comprising those who underwent only anterior spinal fusion (ASF); Group B, comprising those who underwent ASF and revision surgery; and Group C, comprising those who underwent planned ASF plus posterior instrumentation. Data concerning the affected level, bone fusion rate, and progression of the postoperative local kyphosis angle were collected. The risk factors for the progression of local kyphosis angle after ASF were determined using linear regression analysis.
Results: The overall bone fusion rate was 83.2%. No significant differences in the bone fusion rate were detected between the three groups. Postoperative kyphosis did not progress in the thoracic and lumbar spine in the combined Group A+B; however, the kyphosis angle in the combined Group A+B progressed when the affected level occurred in the thoracolumbar region compared with the kyphosis progressive angle in Group C.
Conclusion: In spinal tuberculosis, the fusion rate of ASF with only grafted bone was good; however, in patients affected in the thoracolumbar spine region, posterior instrumentation is desirable because of local kyphosis progression risk after surgery.
Association between healthy lifestyle combinations and periodontitis in NHANES
Authors: Xu Jiani , Huang Yanqiu , Wang Jie , Wang Huilin , Sun Chen , Shi Wentao , Jiang Xinquan 
Published: November 2023

Abstract
Background
Periodontitis is closely associated with systemic diseases. Healthy lifestyle interventions have health-enhancing effects on systemic disorders and periodontitis, but the extent to which healthy lifestyle combinations are associated with periodontitis is unclear. Therefore, this study aimed to investigate the association between periodontitis and different healthy lifestyle combinations.
Methods
5611 participants were included from the National Health and Nutrition Examination Survey (NHANES, 2009–2014). Six healthy lifestyles factors were defined as fulfilling either: non-smoking, moderate drinking, moderate body mass index (BMI), physical activity, healthy sleep and appropriate total energy intake. Then, the adjusted logistic regression models were performed to identify the association between the periodontitis risk and the scoring system composed of six lifestyles (0–6 scale). Finally, different scenarios were dynamically and randomly combined to identify the optimal and personalized combination mode.
Results
Higher healthy lifestyle scores were significantly associated with lower periodontitis risk (p < 0.05). Four lifestyle factors (smoking, drinking, BMI, and sleep) significantly varied between the periodontitis and healthy groups (p < 0.05). Smoking was considered as a strong independent risk factor for periodontitis in both former and current smokers. Results further indicated that the combination of these four lifestyles played the most essential role in determining the magnitude of periodontitis risk (odds ratio [OR]: 0.33; 95% confidence interval [CI]: 0.21 to 0.50). In the total population, the majority of three lifestyle combinations outperformed the two combination models, whereas the two-combination of nonsmoking-drinking (OR: 0.39; 95% CI: 0.27 to 0.58) had relatively lower risk than the three-combination of healthy drinking-BMI-sleep (OR: 0.42; 95% CI: 0.26 to 0.66).
Conclusion
This cross-sectional study suggests that smoking, drinking, BMI, and sleep are significantly related with periodontitis and smoking is the principal risk factor related among them. This study provides various customized lifestyle combinations for periodontitis prevention.
Comparative study of the mouthparts of different feeding crab species in the waters adjacent to the Yangtze River Estuary
Authors: Ding Yue , Yuan Lin , Wu Huixian , Deng Yazhuo , Liu Jingyu , Xue Junzeng 
Published: November 2023

Abstract
The intertidal zone of the Yangtze River estuary is highly heterogeneous and suitable for crabs of various feeding habits. The ability of decapod crabs to occupy various ecological niches is closely related to the structure of their oral appendages during the feeding process. In this study, we investigated the morphological and structural characteristics of the oral appendages of crabs and their relationship with feeding habits, and selected three crab species with different feeding habits in the Yangtze River estuary, namely, Macrophthalmus abbreviatus (detritivorous), Portunus trituberculatus (carnivorous), and Chinomantes haematocheir (phytophagous). Their mouthparts were dissected and placed under a stereomicroscope to observe and photograph the morphological structure of their oral appendages. The results showed that all three crab species had six pairs of oral appendages, which were distributed in the same position in the oral cavity, and the structure of each pair of oral appendages was the same. In terms of appearance and morphological structure, the main differences were in the mandible and the third maxilliped. In terms of setal types, M. abbreviatus existed two obvious special setal structures, spoon-tipped setae, anchor setae and the single row of semi-anchor setae; P. trituberculatus had special unilateral serrated setae; and C. haematocheir did not have peculiar setae. In this paper, we discuss the adaptation of crab oral organ structure and feeding habits, and reveal the influence of estuarine environmental changes on crab distribution, with a view to providing a theoretical basis for the conservation of crab biodiversity in the Yangtze River Estuary.
Efficacy of Combined Exercise and Nutrition Intervention Study for Possible Sarcopenia in Community-Based Primary Care Clinics (ENdSarC): study protocol for a multicenter single-blinded randomized controlled trial
Authors: Ji Woohyuk , Lee Daehyun , Kim Minjin , Lim Nahyun , Lim Jae-Young , Baek Jae Uk , Kim Sungwouk , Lee Choong Hyung , Kim Miji , Won Chang Won 
Published: November 2023

Abstract

Background
Sarcopenia is a geriatric disease characterized by loss of muscle mass and strength. Although combined exercise and nutrition intervention is known to be effective for sarcopenia, clinical trials involving patients with sarcopenia in primary care are scarce. We describe a protocol for a trial to examine the effects of a 12-week combined exercise and nutrition intervention in older Korean adults with possible sarcopenia in community-based primary care.
Methods
This multicenter, randomized, controlled trial will include 94 community-dwelling older participants aged 65–85 years with possible sarcopenia (47 participants in the intervention and control groups each). Resistance exercises, which incorporate concentric and eccentric exercises, will consist of an introductory phase (3 weeks: twice-weekly supervised exercise sessions and once-weekly home exercises; contraction exercises), an expanded phase (3 weeks: twice-weekly supervised exercise sessions and once-weekly home exercises; eccentric exercises), and a maintenance phase (6 weeks: once-weekly supervised exercise sessions and twice-weekly home exercises; power/eccentric exercises). Nutritional supplementation will be provided according to the nutritional status of the participants using a Mini-Nutritional Assessment. Participants will be assessed at baseline, 12 and 24 weeks, and the primary outcome will be the 5-times chair stand test results.
Discussion
To the best of our knowledge, this will be the first clinical trial to evaluate the efficacy of a combined exercise and nutritional supplementation intervention in older patients with possible sarcopenia in community-based primary care clinics. These findings will provide new insights to clinicians regarding the long-term usability for doctors and patients with possible sarcopenia in community-based primary care.
Trial registration:
This trial was prospectively registered at ClinicalTrials.gov on September 16, 2023 (registration number: NCT06049914).