bluuebunny/crossref_metadata_2025_split huggingface dataset:
EFFECTS OF A SINGLE EVENING VINYASA YOGA SESSION ON SLEEP IN ADULTS WITH INSOMNIA SYMPTOMS
Authors: Cheruka Caitlin A. , Sherman Sally A. , Quinn Tyler D. , Giordano Elizabeth G. , Lebegern Sophie M. , Lehrer H. Matthew , Buysse Daniel J. , Davis Kelliann K. , Kline Christopher E. 
Published: February 2024

https://youtu.be/1I7CENnICb4

BACKGROUND
Vinyasa yoga (VY), a form of yoga that links breath with movement and has higher energy expenditure perhaps than most other types of yoga, has been sparsely studied for its effects on sleep among adults with insomnia. It remains unknown whether and how an acute bout of VY performed in the evening impacts sleep and autonomic function. The purpose of this study it to examine the effects of an acute session of VY performed in the evening on sleep and nocturnal heart rate variability (HRV) in adults with insomnia symptoms.

METHODS
33 insufficiently active adults (84.8% female; 78.8% White; age=34.9±10.6 y; body mass index=28.9 kg/m2) with at least mild insomnia symptoms (Insomnia Severity Index ≥ 10) were randomized to either a single 60-min session of VY (n=17) or a quiet rest control condition (CON: n=16) occurring between 15:00 and 20:00 h. VY followed a pre-recorded practice and CON watched a nature documentary. On one night before and after the experimental session, participants wore a wrist accelerometer and a chest heart rate (HR) monitor overnight and completed a sleep diary. HRV was derived from the entire HR recording across the nocturnal period and standardized for sleep duration, with root mean square of successive differences (RMSSD) as the primary outcome. Analyses compared the changes from pre- to post-session between groups using linear mixed models and Cohen’s d effect sizes.

RESULTS
The change in actigraphy-assessed sleep efficiency (SE) and total sleep time (TST) did not differ from pre- to post-session for VY (SE: 88.9±1.4 to 88.9±1.5%; TST: 454.7±15.8 to 445.8±17.4 min) or CON (SE: 89.4±1.4 to 88.7±1.6%; TST: 401.3±16.3 vs. 407.3±17.3 min); group x time interactions were not statistically significant (each p &gt; 0.48). The change in nocturnal RMSSD did not differ from pre- to post-session for either VY (39.5±6.8 to 38.7±6.0 ms) or CON (37.6±7.0 to 35.8±6.2 ms) and the group x time interaction was not statistically significant (p=0.94).

CONCLUSION
An acute bout of VY performed in the early evening did not significantly change accelerometer- or diary-assessed sleep or impact parasympathetic tone during sleep. VY in the early evening is unlikely to benefit or impair sleep in adults with insomnia symptoms.
Between Ibsen and Dostoevsky: “Rewriting the Classics” in Z. N. Gippius’ Story “Mirrors”
Authors: Magomedova Dina М. 
Published: February 2024

Z.N. Gippius’ story “Mirrors” was repeatedly correlated with the plot of F.M. Dostoevsky’s novel Idiot in lifetime criticism and the latest literature. The paper discovers the second source text, which is H. Ibsen’s play “Hedda Gabler.” Comparing the plot details of Dostoevsky’s novel and Ibsen’s drama, we can reveal “male” and “female” love triangles (Myshkin – Nastasya Filippovna – Aglaya, Nastasya Filippovna – Myshkin – Rogozhin; Levborg – Gedda – Thea; Raisa – Jan – Samokhin, Jan – Raisa – Olga). The reinterpretation of plot collisions in “Mirrors” may be considered from the psychological and religious-philosophical point of view. The paper provides with nearly word-by-word textual overlaps in the story with the mentioned sources. The analysis shows that the fundamental difference between the love triangles in Z. Gippius’ story in comparison with the previous tradition is that Gippius is trying to destroy the situation of inevitable choice for her characters. She reinterpreted and rewrote anew the plots of Dostoevsky and Ibsen, while the main characters changing their roles and the triangles collapsing at the end. No Gippius neither Merezhkovsky have articulated the philosophy of a religiously meaningful “triple union” as a form of realization of the “Third Testament” at the time of writing the story. The story “Mirrors” rewrites of the classics and the latest literature destructing of the traditional plots, though not completing and rethinking: the story has an open ending, the ideas of a triple alliance are unfinished. The article conclusion offers the hypothesis that the title of the story itself is not only Plato’s idea of the human existence world as a multiple reflection of the true ideal world in crooked mirrors, which is repeatedly articulated by its characters. It is also the formulated metapoetic principle of creating the text of the story itself, which is built on multiple reflections of familiar literary images and plot situations.
Bioplaguicidas: un sustituto de los plaguicidas químicos
Authors: Carbajal Adriana , Sánchez Miriam , Romero Eric 
Published: February 2024

Las consecuencias de la revolución verde han causado estragos en el equilibrio ecológico. El uso desmedido de plaguicidas para evitar la pérdida de millones de hectáreas de cultivo a la larga ha dado como resultado ciertos problemas como la resistencia a estas sustancias por parte de los organismos considerados como plagas y la bioacumulación en el medio ambiente y en la salud humana. Si bien las plagas representan una amenaza, también así lo son las sustancias comúnmente usadas para combatirlas. El uso alternativo de bioplaguicidas, que se refieren a todas aquellas sustancias de origen natural derivadas de microorganismos, plantas y animales utilizados para el combate de plagas, presenta ventajas sobre los plaguicidas químicos por su alta especificidad sobre las plagas blanco, la ausencia de riesgo para los trabajadores y el medio ambiente, así como el biocontrol como una alternativa para eliminar las poblaciones de insectos plaga.
Pengaruh terapi akupresur pada titik pericardium 6 dan stomach 36 terhadap penurunan intensitas emesis gravidarum trimester 1 di puskesmas Bojonegara
Authors: Ismawati Iis , Wirakusumah Firman F , Raksanagara Ardini Saptaningsih 
Published: February 2024

Emesis gravidarum adalah kondisi mual disertai muntah pada awal kehamilan. Mual muntah dialami sekitar 50%-90% wanita hamil dan mual muntah pada sebagian ibu hamil menyebabkan hilangnya nafsu makan dan mengganggu kegiatan sehari-hari serta dapat membahayakan kesehatan ibu dan janin. Terdapat dua cara dalam menangani emesis gravidarum yaitu dengan pemberian vitamin B6 dan akupresur. Tujuan penelitian: mengukur perbedaan intensitas mual serta muntah terhadap wanita hamil dengan emesis gravidarum sedang dan menganalisis pengaruh akupresur kombinasi vitamin B6 dalam menurunkan frekuensi mual muntah terhadap ibu hamil. Metode : Desain penelitian menggunakan quasy experiment two group pre-post test design. Penelitian dilaksanakan di Puskesmas Bojonegara Kota Serang pada bulan Juni sampai Juli 2019. Pengambilan sampel dilakukan dengan permutation blocked, jumlah sampel sebanyak 64 responden, 32 responden pada kelompok akupresur kombinasi vitamin B6 dan 32 responden pada kelompok vitamin B6 tanpa akupresur. Hasil penelitian dianalisis menggunakan uji T Test dan uji N Gain. Hasil: Hasil analisis didapatkan terjadi penurunan frekuensi mual muntah pada kedua kelompok dan selisih rata-rata skor intensitas mual muntah pada kelompok akupresur kombinasi vitamin B6 yaitu 6,06 sedangkan pada kelompok vitamin B6 yaitu 2,03 (p=0,000). Berdasar hasil analisis menggunakan uji N-Gain pada penggunaan akupresur kombinasi vitamin B6 didapatkan nilai N-Gain skor intensitas mual muntah yaitu 0,91 dalam kategori tinggi, sedangkan pada penggunaan vitamin B6 tanpa akupresur didapatkan hasil nilai N-Gain skor yaitu 0,56 dalam kategori sedang. Simpulan: terjadi penurunan frekuensi mual muntah pada kedua kelompok. Akupresur kombinasi vitamin B6 mempunyai pengaruh dalam menurunkan intensitas mual muntah pada wanita hamil TM 1
Evaluation of Prothrombin Time,International Normalized Ratio, and Activated Partial Thromboplastin Time in Hepatitis B Virus Patients, Sudan2020 -2021
Authors: Modawe GadAllah , Esra Awad Mohamed  , Ozaz Yagoup Mohamed  , AbdelrahmanEldaw Mohammed  , Hiba Awadelkareem Osman Fadl  , Abdelrahman Hamza Abdelmoneim  
Published: February 2024

Background: Hepatitis B virus is a growing problem worldwide leading to increasing incidences of life-threatening complications of which liver diseases play a major part of it.
Materials and Methods: To evaluate these effects in Sudanese patients, a cross-sectional study was carried out in Wad Medani teaching hospital from October 2020 to February 2021 for assessing the effect of the disease on the coagulation profile. Patients were randomly selected according to inclusion and exclusion criteria. 2.5ml of blood samples were collected from each patient in tri-sodium citrate containers, and then semi-automated Coatron M4 was used to estimate Prothrombin Time (PT) and Activated Partial Thromboplastin Time (APTT) after calibrated and controlled setting according to the manufacturer’s instructions. SPSS (version 25) was used to analysed data.
Results: A total of 100 hepatitis B virus patients were included in the study, with males representing (79%) and females were (21%), their age were between 18 to 60 years. The study results showed PT prolonged in (98%) of the study population and only (2%) were normal. regarding the APTT (99%) of them had prolonged results (more than the upper normal), and the remaining (1%) was normal. Also, the study results showed there were slight statistically insignificant differences in coagulation profile in hepatitis B virus patients according to gender, age group, family history, and duration of the disease.
Conclusion: hepatitis B infection had a great effect on Coagulation profiles. Therefore, it is recommended on the basis of these results to request PT, INR, and APTT as routine works up for hepatitis B virus patients.
KONTRIBUSI INTELIJEN TNI AU DALAM MENCEGAH AKSI TERORISME DI LANUD HALIM PERDANAKUSUMA
Authors: Syarief Ahmad , Kemalsyah M. , Abu Supri 
Published: February 2024

One of the task of the TNI AU Intelligence at Halim Perdanakusuma Air Base is to support the implementation of air operations carried out by the Indonesian Air Force so that intelligence must be able to carry out early prevention and early detection of every form of threat that can interfere with air operation, especially in preventing acts of terrorism at Halim Perdanakusuma Air Base. The problems encountered when carrying out these task and looking for applicable solutions in the form of policies and efforts that can be made by policies and efforts that can be made by policu makers as problems solving by considering the strategic environment and predictions of the threat of terrorism at Halim Perdanakusuma Air Base in the future. This artikel uses descriptive analysis method through several literature studies on intelligence, air base security system, and terrorism as well as looking for data in the field that is needed by coordinating with Halim Perdanakusuma Air Base and Dispamsanau. The contribution of Indonesian Air Force Intelligence to prevent acts of terrorism at Halim Perdanakusuma Air Base in the context of supporting air operations can certainly be realized if there is an understanding and “political will” from all parties who have the authority. Synergy of all relevant parties is needed to increase human resources (Indonesian Air Force Intelligence personnel) and the need for special Intelligence material infrastructure related to the threat of terrorism in order to make Halim Perdanakusuma Air Base safe from acts of terrorism and the success of air operations carried out by the Air Force
MetaWin 3: open-source software for meta-analysis
Authors: Rosenberg Michael S. 
Published: February 2024

The rise of research synthesis and systematic reviews over the last 25 years has been aided by a series of software packages providing simple and accessible GUI interfaces which are intuitively easy to use by novice analysts and users. Development of many of these packages has been abandoned over time due to a variety of factors, leaving a gap in the software infrastructure available for meta-analysis. To fulfill the continued demand for a GUI-based meta-analytic system, we have now released MetaWin 3 as free, open-source, multi-platform software. MetaWin3 is written in Python and developed from scratch relative to earlier versions. The codebase is available on Github, with pre-compiled executables for both Windows and macOS available from the MetaWin website. MetaWin includes standardized effect size calculations, exploratory and publication bias analyses, and allows for both simple and complex explanatory models of variation within a meta-analytic framework, including meta-regression, using traditional least-squares/moments estimation.
Kinetics of extracting valuable components from Ti-bearing blast furnace slag by acidolysis with sulphuric acid
Authors: Wang Yan , Gao Xin , He Siqi , Guo Jun 
Published: February 2024

Ti-bearing blast furnace slag is a kind of solid waste produced by Pangang Group Company through the blast furnace smelting method. A variety of valuable components can be extracted from the Ti-bearing blast furnace slag after acidolysis with concentrated sulphuric acid. In order to study the kinetics of acidolysis, this paper investigated the effects of the acidolysis temperature, acid-slag ratio and raw material particle size on the overall extraction rate of Ti4+, Mg2+ and Al3+ components at different reaction times, and simulated the acidolysis process by using the unreacted shrinking core model. The results showed that the acidolysis process was controlled by internal diffusion with an apparent activation energy of 19.05 kJ mol–1 and the semi-empirical kinetic equation of the acidolysis process was obtained.
Metabolomic profiling reveals key metabolites associated with hypertension progression
Authors: Al Ashmar Sarah , Anwardeen Najeha Rizwana , Anlar Gulsen Guliz , Pedersen Shona , Elrayess Mohamed A. , Zeidan Asad 
Published: February 2024

IntroductionPre-hypertension is a prevalent condition among the adult population worldwide. It is characterized by asymptomatic elevations in blood pressure beyond normal levels but not yet reaching the threshold for hypertension. If left uncontrolled, pre-hypertension can progress to hypertension, thereby increasing the risk of serious complications such as heart disease, stroke, kidney damage, and others.ObjectiveThe precise mechanisms driving the progression of hypertension remain unknown. Thus, identifying the metabolic changes associated with this condition can provide valuable insights into potential markers or pathways implicated in the development of hypertension.MethodsIn this study, we utilized untargeted metabolomics profiling, which examines over 1,000 metabolites to identify novel metabolites contributing to the progression from pre-hypertension to hypertension. Data were collected from 323 participants through Qatar Biobank.ResultsBy comparing metabolic profiles between pre-hypertensive, hypertensive and normotensive individuals, six metabolites including stearidonate, hexadecadienoate, N6-carbamoylthreonyladenosine, 9 and 13-S-hydroxyoctadecadienoic acid (HODE), 2,3-dihydroxy-5-methylthio- 4-pentenoate (DMTPA), and linolenate were found to be associated with increased risk of hypertension, in both discovery and validation cohorts. Moreover, these metabolites showed a significant diagnostic performance with area under curve &gt;0.7.ConclusionThese findings suggest possible biomarkers that can predict the risk of progression from pre-hypertension to hypertension. This will aid in early detection, diagnosis, and management of this disease as well as its associated complications.
Dietary antioxidant intake increases ankle brachial pressure index in men but not in women: a cross-sectional study
Authors: Wang Yuting , Wang Jianfeng 
Published: February 2024

ObjectiveAtherosclerosis is a significant cause of cardiovascular and cerebrovascular diseases, with a greater impact on men than women. Dietary antioxidant intake is inversely related to the risk of atherosclerosis development. We aimed to investigate the association between dietary composite antioxidant intake and the ankle brachial pressure index (ABPI). The ABPI is not only used for assessing the progression of arterial lesions but also for stratifying the risk of atherosclerotic disease.MethodsWe conducted a cross-sectional analysis involving 1,049 participants from the National Health and Nutrition Examination Survey (NHANES). We examined six antioxidants (zinc, selenium, carotenoids, and vitamins A, C, and E) and a composite dietary antioxidant index (CDAI) derived from these antioxidants as exposure variables. The primary outcomes encompassed cardio-metabolic parameters, including body mass index (BMI), body fat mass (BFM), systolic and diastolic blood pressure, triglycerides, HDL and LDL cholesterol, C-reactive protein, and the Ankle-Brachial Pressure Index (ABPI). Associations and interactions between variables were assessed using linear regression analyses. Moreover, mediation and moderation analysis is employed.ResultsHierarchical multiple regression analysis revealed that among men, dietary intake of zinc, selenium, and vitamin A remained positively associated with a higher ABPI even after adjusting for covariates. Conversely, in the stratified regression analysis based on CDAI quartiles, a U-shaped association between CDAI and ABPI was suggested. Notably, no significant association between dietary antioxidant intake and ABPI was observed among women. CDAI, intake of Vitamin A, Vitamin C, and Vitamin E do not influence all-cause death through mediation by abpi, but rather have a direct effect on all-cause death. Moreover, there is a significant interaction between the intake of Vitamin A and gender, where a daily intake of Vitamin A more than 776 ug is especially beneficial for women.ConclusionThe combined intake of nutrients with antioxidant properties may prevent the initiation and progression of atherosclerosis and influence the outcome in a sex-specific manner.
Redox and melting characteristics of Mn-based ores for high-temperature thermochemical energy storage
Authors: Liu Lei , Xu Wenting , Liu Hanzi 
Published: February 2024

Redox and melting characteristics of Mn-based ores were investigated to test their potential use in thermochemical energy storage (TCES). Two Mn-based materials (FJ and LY) were natural ores with the Mn content higher than 35 wt%, and one Mn-based material was prepared by adding an MgO–kaolin inert support into LY ores to increase its melting temperature. Cyclic reduction and oxidation reactivity of these Mn-based materials was studied via thermogravimetric analysis (TGA), and the melting behaviors of these materials were investigated by using a melting test setup with an optical camera–image system. It was found that the oxygen capacity of the FJ Mn ore can approach ∼1.50 wt%, while the LY Mn ore had only 0.42 wt%–0.69 wt% oxygen capacity The deformation temperature of the FJ Mn ore is higher than that of the LY Mn ore, and the melting temperatures of the LY Mn ore can be significantly improved with the addition of an MgO–kaolin inert support, while the reactivity is decreased due to the addition of the MgO–kaolin inert material. This study proves that manganese ores with high oxygen capacity and deformation temperature have potential as TCES materials. For some manganese ores with low deformation temperatures, it is necessary to improve their melting temperatures and ensure oxygen capacity for high-temperature TCES applications.
In silico identification of human microRNAs pointing centrin genes in Leishmania donovani: Considering the RNAi-mediated gene control
Authors: Aljedaie Manei M. , Alam Pravej 
Published: February 2024

Leishmaniasis, a parasitic disease caused by different species of the protozoa parasite Leishmania, is a neglected tropical human disease that is endemic in about a hundred countries worldwide. According to the World Health Organization (WHO), the annual incidence of cutaneous leishmaniasis (CL) is estimated to be 0.7–1.2 million cases globally, whereas the annual incidence of visceral leishmaniasis is estimated to be 0.2–0.4 million cases. In many eukaryotic organisms, including human beings and protozoan parasites, centrin genes encode proteins that play essential roles within the centrosome or basal body. Human microRNAs (miRNAs) have been linked to several infectious and non-infectious diseases associated with pathogen–host interactions, and they play the emphatic roles as gene expression regulators. In this study, we used the MirTarget bioinformatics tool, which is a machine learning-based approach implemented in miRDB, to predict the target of human miRNAs in Leishmania donovani centrin genes. For cross-validation, we utilized additional prediction algorithms, namely, RNA22 and RNAhybrid, targeting all five centrin isotypes. The centrin-3 (LDBPK_342160) and putative centrin-5 (NC_018236.1) genes in L. donovani were targeted by eight and twelve human miRNAs, respectively, among 2,635 known miRNAs (miRBase). hsa-miR-5193 consistently targeted both genes. Using TargetScan, TarBase, miRecords, and miRTarBase, we identified miRNA targets and off-targets in human homologs of centrin, inflammation, and immune-responsive genes. Significant targets were screened based on GO terminologies and KEGG pathway-enrichment analysis (Log10 p-value &gt;0.0001). In silico tools that predict the biological roles of human miRNAs as primary gene regulators in pathogen–host interactions help unravel the regulatory patterns of these miRNAs, particularly in the early stages of inflammatory responses. It is also noted that these miRNAs played an important role in the late phase of adaptive immune response, inclusively their impacts on the immune system’s response to L. donovani.
Conditional survival analysis and dynamic prediction of long-term survival in Merkel cell carcinoma patients
Authors: Zhang Jin , Xiang Yang , Chen Jiqiu , Liu Lei , Jin Jian , Zhu Shihui 
Published: February 2024

BackgroundMerkel cell carcinoma (MCC) is a rare type of invasive neuroendocrine skin malignancy with high mortality. However, with years of follow-up, what is the actual survival rate and how can we continually assess an individual’s prognosis? The purpose of this study was to estimate conditional survival (CS) for MCC patients and establish a novel CS-based nomogram model.MethodsThis study collected MCC patients from the Surveillance, Epidemiology, and End Results (SEER) database and divided these patients into training and validation groups at the ratio of 7:3. CS refers to the probability of survival for a specific timeframe (y years), based on the patient’s survival after the initial diagnosis (x years). Then, we attempted to describe the CS pattern of MCCs. The Least absolute shrinkage and selection operator (LASSO) regression was employed to screen predictive factors. The Multivariate Cox regression analysis was applied to demonstrate these predictors’ effect on overall survival and establish a novel CS-based nomogram.ResultsA total of 3,843 MCC patients were extracted from the SEER database. Analysis of the CS revealed that the 7-year survival rate of MCC patients progressively increased with each subsequent year of survival. The rates progressed from an initial 41–50%, 61, 70, 78, 85%, and finally to 93%. And the improvement of survival rate was nonlinear. The LASSO regression identified five predictors including patient age, sex, AJCC stage, surgery and radiotherapy as predictors for CS-nomogram development. And this novel survival prediction model was successfully validated with good predictive performance.ConclusionCS of MCC patients was dynamic and increased with time since the initial diagnosis. Our newly established CS-based nomogram can provide a dynamic estimate of survival, which has implications for follow-up guidelines and survivorship planning, enabling clinicians to guide treatment for these patients better.