bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modifiable Lifestyle Factors, Genetic Risk, and Incident Peripheral Artery Disease Among Individuals With Type 2 Diabetes: A Prospective Study
Authors: Zhu Kai , Qian Frank , Lu Qi , Li Rui , Qiu Zixin , Li Lin , Li Ruyi , Yu Hancheng , Deng Yulei , Yang Kun , Pan An , Liu Gang 
Published: January 2024

OBJECTIVE
To prospectively evaluate the association between modifiable lifestyle factors and peripheral artery disease (PAD) among individuals with type 2 diabetes (T2D).

RESEARCH DESIGN AND METHODS
We included 14,543 individuals with T2D from the UK Biobank. We defined a weighted healthy lifestyle score using nonsmoking, regular physical activity, high-quality diet, moderate alcohol consumption, optimal waist-to-hip ratio, and adequate sleep duration, and categorized into unfavorable, intermediate, and favorable lifestyles. We created a genetic risk score (GRS) using 19 single nucleotide polymorphisms previously found to be associated with PAD. We modeled the association between lifestyle score and PAD, overall and stratified by PAD genetic susceptibility.

RESULTS
After a median 13.5 years of follow-up, 628 incident cases of PAD were documented. A linear inverse association between the weighted lifestyle score and PAD was observed, with a hazard ratio (HR) (95% CI) of 0.27 (0.19, 0.38) for favorable compared with unfavorable lifestyle (Ptrend &lt; 0.0001). An estimated 58.3% (45.0%, 69.1%) of PAD in this population could be potentially avoidable if all participants attained a favorable lifestyle. Moreover, the PAD GRS was associated with increased PAD risk (HR [95% CI] per SD increment: 1.13 [1.03, 1.23]). A favorable lifestyle was able to partially mitigate the excess risk of PAD associated with higher GRS, albeit as a nonsignificant interaction. Several biomarkers in the lipid metabolism, hepatic/renal function, and systemic inflammation pathways collectively explained 13.3% (8.5%, 20.1%) of the association between weighted lifestyle score and PAD.

CONCLUSIONS
A favorable lifestyle was associated with lower risk of PAD among individuals with T2D, independent of genetic predisposition to PAD.
Leisure-Time Physical Activity May Attenuate the Impact of Diabetes on Cognitive Decline in Middle-Aged and Older Adults: Findings From the ELSA-Brasil Study
Authors: Feter Natan , de Paula Danilo , dos Reis Rodrigo Citton P. , Raichlen David , Patrão Ana Luísa , Barreto Sandhi Maria , Suemoto Claudia Kimie , Duncan Bruce B. , Schmidt Maria Inês 
Published: January 2024

OBJECTIVE
To assess leisure-time physical activity (LTPA) as a modifier of the diabetes/cognitive decline association in middle-aged and older participants in the Estudo Longitudinal de Saude do Adulto (ELSA-Brasil) study.

RESEARCH DESIGN AND METHODS
ELSA-Brasil is a cohort of 15,105 participants (age 35–74 years) enrolled between 2008 and 2010. We evaluated global cognitive function, summing the scores of six standardized tests evaluating memory and verbal fluency, including the Trail-Making Test, at baseline and follow-up. Incident cognitive impairment was defined as a global cognitive function score at follow-up lower than −1 SD from baseline mean. Participants reporting ≥150 min/week of moderate to vigorous LTPA at baseline were classified as physically active. We assessed the association of LTPA with global cognition change in those with diabetes in the context of our overall sample through multivariable regression models.

RESULTS
Participants’ (N = 12,214) mean age at baseline was 51.4 (SD 8.8) years, and 55.5% were women. During a mean follow-up of 8.1 (SD 0.6) years, 9,345 (76.5%) inactive participants and 1,731 (14.1%) participants with diabetes at baseline experienced faster declines in global cognition than those who were active (β = −0.003, −0.004, and −0.002) and those without diabetes (β = −0.004, −0.005, and −0.003), respectively. Diabetes increased the risk of cognitive impairment (hazard ratio [HR] 1.71; 95% Cl 1.22, 2.39) in inactive but not in active adults (HR 1.18; 95% CI 0.73, 1.90). Among participants with diabetes, those who were active showed a delay of 2.73 (95% CI 0.94, 4.51) years in the onset of cognitive impairment.

CONCLUSIONS
In adults living with diabetes, LTPA attenuated the deleterious association between diabetes and cognitive function.
Low-Dose Colchicine in Patients With Type 2 Diabetes and Recent Myocardial Infarction in the Colchicine Cardiovascular Outcomes Trial (COLCOT)
Authors: Roubille François , Bouabdallaoui Nadia , Kouz Simon , Waters David D. , Diaz Rafael , Maggioni Aldo P. , Pinto Fausto J. , Grégoire Jean C. , Gamra Habib , Kiwan Ghassan S. , Berry Colin , López-Sendón José , Koenig Wolfgang , Delorme Laurent , Elbaz Meyer , Coste Pierre , Provencher Mylène , Bassevitch Zohar , Blondeau Lucie , L’Allier Philippe L. , Guertin Marie-Claude , Tardif Jean-Claude 
Published: January 2024

OBJECTIVE
The cardiovascular benefits of low-dose colchicine have been demonstrated in patients with coronary disease. Its effects were evaluated in this prespecified analysis in patients with type 2 diabetes (T2D) from the Colchicine Cardiovascular Outcomes Trial (COLCOT).

RESEARCH DESIGN AND METHODS
COLCOT was a randomized, double-blinded trial of colchicine, 0.5 mg daily, versus placebo initiated within 30 days after a myocardial infarction.

RESULTS
There were 959 patients with T2D enrolled and monitored for a median of 22.6 months. A primary end point event occurred in 8.7% of patients in the colchicine group and in 13.1% in the placebo group (hazard ratio 0.65; 95% CI 0.44–0.96; P = 0.03). Nausea was reported in 2.7% and 0.8% in the study groups (P = 0.03), and pneumonia occurred in 2.4% and 0.4% (P = 0.008).

CONCLUSIONS
Among patients with T2D and a recent myocardial infarction, colchicine, 0.5 mg daily, leads to a large reduction of cardiovascular events. These results support the conduct of the COLCOT-T2D trial in primary prevention.
Short-term Results of the Masking Effect of an Infiltrant Resin on Mild Molar Incisor Hypomineralization Lesions in Anterior Teeth
Authors: Sanfelice EB , Heck AB da Silva , Bittencourt HR , Weber JBB , Burnett LH , Spohr AM 
Published: January 2024

SUMMARY
This non-controlled clinical study evaluated the masking effect of an infiltrant resin on mild molar incisor hypomineralization (MIH) lesions. Thirty MIH-affected anterior teeth with creamy/ white opacities from 12 children aged 6-15 years received the application of an infiltrant resin (Icon- DMG). Standard photographs were taken before (T1), immediately after (T2), and 1 week after (T3) resin infiltration. Two calibrated examiners qualitatively analyzed the color match using the Fédération Dentaire Internationale (FDI) scale. The binomial distribution test analyzed the scores of the color match at T1 with T2 and T3, and McNemar’s test analyzed the scores of the color match between T2 and T3 (α=0.05). There was a significant increase in color match between T1 and T2 (p=0.0005), between T1 and T3 (p=0.0005), and between T2 and T3 (p=0.0019). It was concluded that infiltrant resin was effective in improving the esthetic appearance of creamy/white opacities on MIH-affected anterior teeth.
Meningkatkan Ekonomi Masyarakat Gapoktan Pujo Makmur Melalui Pemanfaatan Daun Tanaman MPTS Menjadi Produk Ecoprint
Authors: Surnayanti Surnayanti , Tsani Machya Kartika , Harianto Sugeng Prayitno , Santoso Trio , Dewi Bainah Sari , Rusita Rusita , Rachmah Widya Anisa , Rofi Muhammad , Maharani Danti , Jaya Nuril Atma , Prasetyo Mohamad Arif , Permana Muhammad Agung , Wistary Mirza , Maharany Octavia Widya , Daud Nabila , Nasution Siska Dewi Mauly , Sulindri Sulindri , Amal Muhammad Ikhlasul , Arioen Refi 
Published: January 2024

Membatik saat ini tidak hanya menggunakan media kain putih dan canting saja, namun saat ini membatik bisa menggunakan tanaman yang ada di sekitar kita. Biasanya bagian tanaman yang dimanfaatkan seperti dedaunan, bunga dan buah. Salah satu tanaman yang dapat digunakan yaitu tanaman MPTS (Multi Purpose Tree Species). Pengabdian ini bertujuan untuk meningkatkan ekonomi masyarakat dalam pemanfaatan dedaunan menjadi sebuah produk yang memiliki nilai ekonomi serta diharapkan dapat menjadi peluang usaha Pengabdian kepada masyarakat ini dilakukan di Gapoktan Pujo Makmur Desa Banjaran Kecamatan Padang Cermin Kabupaten Pesawaran. Metode yang digunakan yaitu metode pounding atau dengan teknik pukul yang dilakukan secara manual. Kegiatan ini diawali dengan prestest yang diikuti masyarakat dan demonstrasi yang dilakukan oleh perwakilan mahasiswa, kemudian dilanjutkan dengan pelatihan dan ditutup dengan kegiatan postest yang dilakukan oleh peserta secara berkelompok. Kegiatan pengabdian telah dihadiri oleh 30 peserta. Hasil pengabdian ini mampu menghasilkan berbagai jenis produk seperti jilbab dan baju yang telah diterapkan dan dipakai produk tersebut oleh ibu-ibu Gapoktan Pujo Makmur.
Students vs Lecturers: How Should Writing be Taught and Learned?
Authors: Rozimela Yenni , Anwar Desvalini , Ovilia Ririn , Addinna Ainul 
Published: January 2024

There have been a number of studies investigating the hindrances that students face and their preferences in writing activities. Yet, there raises questions whether all the students’ preferences should be implemented and whether lecturers should comply with all the preferences in order to create an ideal model of teaching and learning writing. Using R & D method, this present study aimed to develop Reading-Based Model of Teaching Academic Writing. This article reports the result of the first stage of the study- the needs analysis. The data were collected through questionnaires distributed to 127 university students and in-depth interview with four writing lecturers. The students’ voice of their preferences in writing activities with the lecturers’ views on an ideal writing class based on their experiences and knowledge of teaching writing were examined and compared. The results revealed that there were agreements and discrepancy between students’ and lecturers’ perception about stages in writing process, students’ ability to develop ideas, knowledge of text genres, the implementation of writing strategies, and the practice of corrective feedback. This study was expected to shed a light on how writing should be better taught and learned.
Examining the Legal Standing of IKN Authority Regulations within Indonesian’s Legislation System
Authors: Harry Setya Nugraha  , Al Arif M. Yasin , Fikri Mhd Zakiul 
Published: January 2024

This study scrutinizes the status of the regulations enacted by the Nusantara Capital City Authority (IKN Authority) within the Indonesian legislative hierarchy, based on Law Number 3 of 2022, also known as the IKN Law. A normative research approach underpins this analysis, utilizing legislative and conceptual methodologies. The investigation concludes that the IKN Law’s Article 5 paragraph 6, was drafted to accommodate all regulations formulated by the IKN Authority. These regulations, born out of the authority's attribution, hold an equivalent standing to those issued by a minister, institution, or agency at the central level given that the IKN Authority is an institution at the ministerial level. Consequently, the formulation of these regulations adheres to the rules governing central-level regulations, with the Supreme Court conducting their review. The unique aspect is the subject matter, which relates to the governance structure of the IKN Authority. Moreover, the formulation of regulations by the IKN Authority should: 1) Define the IKN entity’s position as a unique regional government entity; 2) Outline the types of regulations to be enacted; 3) Clarify the source of authority, which is attribution-based; 4) Specify its position in the hierarchy, equivalent to Regional Regulations; 5) Detail the formulation process and treatment, aligning it with the creation of regional legal products; 6) Elucidate the subject matter of the Regulatory Authority; and 7) Highlight the review process, which can be escalated to the Supreme Court.
Effectiveness of Fermented Coffee Cherry Liquid Extract on Preference of Coffee Berry Borer (Hypothenemus hampei Ferrari) at Coffee Plantation
Authors: Rasiska Siska , Widiantini Fitri , Nadhira Nadhira 
Published: January 2024

Coffee Berry Borer (Hypothenemus hampei Ferrari) are the major pest of coffee crops that can cause damage up to 40 percent. One attempt to control CBB was to use an attractant from the coffee cherry, whose potential can be enhance by fermentation. Fermented coffee will produce metabolites, such as lactic acid, ethanol, and ethyl acetate, which can increase the complexity of the aroma. The study aims to determine the effect of the fermented coffee cherry liquid extract on CBB attractiveness, assess the intensity of the CBB attack, and other insects trapped. The method used in this research is an experiment designed in groups at the site of people’s coffee plantations, Sindangsari Village, Sukasari-Sumedang District. The treatment in this study was a fermented coffee cherry liquid extract, with a volume of aquadest (150ml), 90ml, 120ml, and 150ml, thus obtaining 9 treatments, and each repeated 3 times. Other insects trapped was identified in Pest Laboratory-Universitas Padjadjaran. The results showed that the treatment of wet fermented coffee cherry liquid extract and the volume of 120ml and 150ml could trap CBB better than the other treatments, but did not affect the intensity of CBB attack on coffee plants. Other trapped insects were dominanted by the Coleoptera order of the Staphillinidae family that acted as predators and Diptera of the Drosophillidae family wich acted like herbivores. Thus, fermented coffee fruit liquid extract can be used as a CBB attractant, but its use for the purpose of controlling CBB needs to be well designed so that it does not have a negative impact on natural enemies or other non-target insects.
The CO2 Capture System with a Swing Temperature Moving Bed
Authors: Kozak-Jagieła Ewa , Rerak Monika , Zima Wiesław , Cebula Artur , Grądziel Sławomir , Mondino Giorgia , Blom Richard , Nord Lars O. , Skjervold Vidar T. 
Published: January 2024

Abstract
The reduction in CO2 emissions is now a very popular topic. According to the International Energy Agency, CO2 emitted in 2021 was 6% more than that emitted in 2020. Carbon capture and storage (CCS) is gaining popularity as a possible solution to climate change. Experts estimate that industry and power plants will be responsible for 19% of total CO2 emissions by 2050. This paper presents the design of a semi-industrial-scale system for CO2 capture based on the moving bed temperature swing adsorption technology. According to the results of laboratory tests conducted by the SINTEF industry, this technology demonstrates high capture efficiency (>85%). The CO2 capture medium involved in adsorption is activated carbon passing through individual sections (cooling, heating, adsorption), where CO2 is bonded and then released. The heat and mass transfer processes are realised on the developed stand. The heat exchangers use steam and water as the heating/cooling medium. The paper reviews the existing solutions and describes the developed in-house design of heat exchangers that will ensure heat transfer conditions being a trade-off between economic and efficiency-related issues of the CO2 capture process. The designed test stand will be installed in a Polish power plant and is expected to meet the method energy intensity target, set at ≤ 2.7 MJ/kg CO2, with a capture efficiency exceeding 85%. The aim of the work was to develop and solve technical problems that would lead to the construction of a CO2 capture station with parameters mentioned above. This stand uses an innovative method where CO2 is captured by contacting the fluid (gases) with solid particles. The heat exchange associated with the heating and cooling of the adsorbent had to be solved. For this purpose, heat exchangers were designed with high thermal efficiency and to prevent the formation of mounds.
Elementary Number Theory Problems. Part XII – Primes in Arithmetic Progression
Authors: Grabowski Adam 
Published: January 2024

Summary
In this paper another twelve problems from W. Sierpiński’s book “250 Problems in Elementary Number Theory” are formalized, using the Mizar formalism, namely: 42, 43, 51, 51a, 57, 59, 72, 135, 136, and 153–155. Significant amount of the work is devoted to arithmetic progressions.
Tarski Geometry Axioms. Part V – Half-planes and Planes
Authors: Coghetto Roland , Grabowski Adam 
Published: January 2024

Summary
In the article, we continue the formalization of the work devoted to Tarski’s geometry – the book “Metamathematische Methoden in der Geometrie” by W. Schwabhäuser, W. Szmielew, and A. Tarski. We use the Mizar system to formalize Chapter 9 of this book. We deal with half-planes and planes proving their properties as well as the theory of intersecting lines.
Evaluation of solid-phase panreactivity with negative direct antiglobulin testing
Authors: Little J.T. , Blackall D.P. 
Published: January 2024

Abstract
Solid-phase red cell adherence (SPRCA) is a sensitive platform for antibody detection, but nonspecific reactions may occur. One pattern of apparent nonspecific reactivity is a panagglutinin with a negative direct antiglobulin test (DAT). The purpose of this study was to define the clinical characteristics of patients with these nonspecific reactions and their associated serologic findings. Twenty patients with panreactive SPRCA testing results were identified between November 2022 and May 2023. In addition to panagglutinins, these patients had (1) a negative polyethylene glycol (PEG) antibody detection test, (2) a negative PEG autocontrol, and (3) a negative DAT. The strength of SPRCA panreactivity and the results of eluate testing (by tube and SPRCA) were studied. Clinical characteristics of patients included age, sex, and primary diagnosis. Each patient was also assessed for evidence of hemolysis. Fourteen female and six male patients were evaluated (average age 44 years). Primary diagnoses included pregnancy (n = 10), acute bleeding (n = 4), orthopedic (n = 3), and other (n = 3). There was no clinical or laboratory evidence of hemolysis. The predominant strength of SPRCA panreactivity was evenly distributed across reaction grades (1+ to 3+). Fifty-five percent of the eluates tested in PEG showed panreactivity, consistent with warm-reactive autoantibodies, while 85 percent of eluates tested by SPRCA were panreactive. Six discrepant cases, in which PEG eluate testing was negative and solid-phase eluate testing showed panreactivity, were associated with weak solid-phase plasma panreactivity (1+). In addition, the reactivity strengths of the eluates tested by SPRCA were invariably more strongly reactive than those eluates tested in PEG. Panagglutination is a distinct SPRCA-only plasma reactivity pattern. Despite a negative PEG tube and DAT, most panagglutinins are warm-reactive autoantibodies. Fortunately, these “interfering” panagglutinins do not appear to be clinically significant and are easily managed by an alternative testing method such as PEG.
Response of Fresh-Cut Iceberg Lettuce to Fumigation with Botanical Essential Oils
Authors: Grzegorzewska Maria , Szczech Magdalena , Kowalska Beata , Wrzodak Anna 
Published: January 2024

Abstract
The study was conducted on iceberg lettuce ‘Ice Wave F1’. The effect of prestorage treatment with seven essential oils (EOs) of rosemary, peppermint, basil, thyme, marjoram, lemon, and oregano on the quality of cut lettuce was evaluated. The lettuce was fumigated with EOs for two hours in airtight containers. Two concentrations of EOs were used: 16.7 μL·L−1 and 33.3 μL·L−1. Fumigation with rosemary and thyme EOs lowered the browning of fresh-cut iceberg lettuce and thus the deterioration of its appearance during six days of storage. Lettuce fumigated with thyme EO scored relatively high in sensory quality and consumer acceptability. Lettuce fumigated with rosemary EO was characterized by high intensity of aroma and herbal flavor, significantly lowering its sensory rating. Marjoram EO at a dose of 16.7 μL·L−1 resulted in the fastest browning of lettuce cut surface and relatively reduced the market value during storage. Other EOs had no significant effect on the quality of cut lettuce during shelf life. It was also found that fumigation did not change bacteria, fungi, and mold populations on fresh-cut iceberg lettuce during short-term storage. The results obtained in the study showed that fumigation with thyme oil at a concentration of 33.3 μL·L−1 is most recommended for use in the storage of fresh-cut iceberg lettuce, but implementing these results into practice requires further research.
Detection and Molecular Characterization of Peach Latent Mosaic Viroid Isolates Infecting Stone Fruit Trees in Poland
Authors: Cieślińska Mirosława 
Published: January 2024

Abstract
Field surveys were carried out to assess the incidence of peach latent mosaic viroid in nine orchards of stone fruit trees in four growing regions of Poland. Forty of 119 peaches, six of 37 apricots, five of eight nectarines and one of four plums trees tested positive by RT-PCR for this viroid. Most of the infected stone fruit trees did not show any symptoms. Leaf yellow mosaic was only noticed on ‘Maycrest’ peach and ‘Saturn’ nectarine trees, and additional symptoms of cracked fruits with corky sutures and enlarged pits were observed on one ‘Maycrest’ tree. One or two isolates from each orchard and each species of infected tree were selected, and together, 11 isolates of peach latent mosaic viroid were used for genetic analyses. The nucleotide sequence similarity of selected isolates found in Poland was 93.6–100%. They shared 82.0–98.8% similarity with the viroid strains from different hosts and geographical regions. The phylogenetic analysis led to the clustering of all isolates detected during this study in the most numerous represented subgroup II-A, composed of peach latent mosaic viroid strains originating from different geographic regions and host plants. Although Polish isolates were clustered in the same subgroup, some differed in length and nucleotide sequences. It was shown that the genetic variability of isolates found in Poland was unrelated to the regions of their origin. A positive signal was obtained in dot-blot hybridization of all analyzed 11 isolates.
The Use of Hydrogen Peroxide and Silver Nanoparticles in Horticulture
Authors: Orlikowski Leszek , Sas-Paszt Lidia , Wojdyła Adam , Orlikowska Teresa 
Published: January 2024

Abstract
Both hydrogen peroxide and silver can oxidize organic and inorganic molecules, and this causes them to affect the metabolism of living organisms in many ways. The paper presents examples of the impact of H2O2 and silver on stimulating plant growth and development and increasing plants’ resistance to biotic and abiotic stresses. The most underlined proposal for application in horticulture is the control of microorganisms during cultivating and storing vegetables, fruits, and flowers, aiming to replace synthetic pesticides. Preparations containing H2O2, silver, or both components can be widely used in horticulture for plant protection, in the form of spraying and soaking seedlings, to protect them during the time of storage, for disinfecting tubers, bulbs, and rhizomes before planting, for fogging potatoes and root vegetables during storage, for quick healing of wounds on the roots and aboveground parts of plants, after cutting and in the case of frost damage and injuries caused by winds, for disinfecting seeds, and, as stimulants of plant development and inducers of resistance to biotic and abiotic stresses. However, their practical use depends on obtaining the legislator’s consent for their broader use in horticultural production.