bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing pulmonary congestion in patients hospitalized with decompensated chronic heart failure according to lung ultrasound and remote dielectric sensing (ReDS)
Authors: Kobalava Zh. D. , Safarova A. F. , Tolkacheva V. V. , Zorya O. T. , Cabello Montoya F. E. , Nazarov I. S. , Lapshin A. A. , Smirnov I. P. , Khutsishvili N. I. , Galochkin S. A. , Vatsik-Gorodetskaya M. V. 
Published: January 2025

Aim. To conduct a comparative assessment of parameters and dynamics of pulmonary congestion according to lung ultrasound and remote dielectric sensing (ReDS) in patients hospitalized with decompensated chronic heart failure (CHF).Materials and methods. The pilot single-center study included patients hospitalized with decompensated CHF. Lung ultrasound and ReDS were simultaneously performed within 24 hours from the moment of hospitalization and at discharge. Eight-zone lung ultrasound was performed with the calculation of the sum of B-lines. Pulmonary congestion was confirmed with the sum of B-lines ≥ 5. ReDS was performed according to the manufacturer’s protocol. Congestion was confirmed at the value of more than 35%. To determine ReDS interoperator variability, each patient was examined by two operators who were blind to each other’s findings with a 20–30-minute interval.Results. Thirty-five patients were included in the study: 40% (n = 14) men, the average age was 71 (65.5; 78.5) years, the median NT-proBNP was 1,379 (470; 4,277) pg / l. Hydrothorax at admission was observed in 31,4% (n = 11) of patients. The incidence of pulmonary congestion according to lung ultrasound was 57.1% (n = 20): 31.4% (n = 11) of patients had mild congestion, 22.9% (n = 8) – moderate, and 2.9% (n = 1) – severe congestion. ReDS data revealed pulmonary congestion in 62.9% (n = 22) of cases, of which 37,1% (n = 13) of cases were characterized by mild, 22.9% (n = 8) – by moderate, and 2.9% (n = 1) – by severe congestion. A moderate correlation was found between ReDS (%) and lung ultrasound (sum of B-lines) findings at admission (Spearman’s rank correlation coefficient = 0.402; p = 0.017). No correlation between the two methods was found at discharge (p = 0.613). The frequency of agreement between lung ultrasound and ReDS on signs of congestion at admission was 77.1% (p = 0.004) with an average Cohen’s Kappa coefficient (κ = 0.53). The average interoperator variability in ReDS was 9.9%.Conclusion. A moderate correlation was revealed between ReDS (%) and lung ultrasound (sum of B-lines) in detecting pulmonary congestion (Spearman’s rank correlation coefficient = 0.402; p = 0.017). No correlation between the two methods was found at discharge (p = 0.613).
Pengembangan e-modul berbasis flip builder pada pokok bahasan larutan elektrolit dan non elektrolit kelas X
Authors: Tualena Lidya Kristina , Rombe Yunita Pare , Murtihapsari Murtihapsari 
Published: January 2025

<p>Tujuan dari penelitian ini adalah menganalisis tingkat kevalidan, kepraktisan, dan respon siswa terhadap penggunaan E-Modul larutan elektrolit dan non-elektrolit yang dikembangkan dengan aplikasi <em>Flip Builder</em>. Metode penelitian adalah <em>Research &amp; Development</em> (R&amp;D) pendekatan model ADDIE, yang mencakup lima tahapan: <em>Analysis</em>, <em>Design</em>, <em>Develop</em>, <em>Implementation</em>, dan <em>Evaluation</em>. Teknik analisis data yaitu observasi, wawancara, lembar validasi, dan angket yang diisi oleh peserta didik. Berdasarkan penelitian diperoleh hasil bahwa <em>E-Modul </em>yang dikembangkan memiliki tingkat validitas sebesar 91.96%. Hasil angket respon siswa tingkat kepraktisan diperoleh hasil sebesar 76.10% sehingga E-Modul larutan elektrolit dan Non Elektrolit valid dan praktis. Sehingga aktivitas dalam belajar mengajar dapat lebih jelas, efektif, efesien dan interaktif dalam mencapai tujuan pembelajaran.</p><p> </p><p><strong><em>Development of e-modules based on flip builder on the subject of electrolyte and non-electrolyte solutions class X</em></strong><strong><em></em></strong></p><p> </p><p><strong><em>Abstra</em></strong><strong><em>ct</em></strong><strong><em>: </em></strong><em>This study aims to find out how to develop and determine the level of validity and practicality of the flip builder-based E-Module, as well as to find out the students' responses to the E-Module developed. This research method is Research &amp; Development (R&amp;D) using the ADDIE model which includes the Analysis, Design, Development, Implementation, and Evaluation stages. Data collection tools in this study are observation, interviews, validation sheets, and student questionnaire sheets. Based on the results of the study the E-Module developed through the analysis stage (problem determination analysis and needs analysis), the design stage (designing the needs, objectives, content, and structure, visual design of the E-Module), the development stage (developing, and validating the E-Module in accordance with the suggestions of the validator) implementation (conducting trials of products that have been developed) and evaluation (E-Module in the final revision evaluation of the developed product). The research results from the assessment of the E-Modul validator developed have a validity level of 91.96%. Based on the results of the student response questionnaire, the practicality level was 76.10% so the electrolyte and non-electrolyte solution E-Modules were valid and practical to use.</em><em></em></p>
Analisis Kesalahan Siswa pada Tes Kemampuan Dasar Matematika Siswa Kelas III SD Negeri 1 Kedawung Tahun Ajaran 2019/2020
Authors: Wati Monalisa Darma , Wahyudi Wahyudi , Susiani Tri Saptuti 
Published: January 2025

<p>Tujuan penelitian ini adalah untuk menganalisis jenis, faktor penyebab dan alternatif solusi mengatasi kesalahan siswa dalam menyelesaikan soal Tes Kemampuan Dasar Matematika. Penelitian ini merupakan penelitian kualitatif dengan pendekatan studi kasus. Teknik pengumpulan data pada penelitian ini yaitu, tes, wawancara dan studi dokumen. Alat pengumpulan data yang digunakan adalah tes kemampuan dasar matematika dan pedoman wawancara. Subjek penelitian ini berjumlah 19 siswa dan 1 guru kelas III SD Negeri 1 Kedawung. Hasil penelitian menunjukkan: (1) jenis kesalahan siswa yaitu <em>reading error</em> sebesar 10,98%, <em>comprehension error</em> sebesar 11,53% , <em>transformation error</em> sebesar 16,48%, <em>process skill error</em> 48,90 %, dan <em>encoding error</em> sebesar 12,08%; (2) faktor penyebab yaitu (a) <em>Reading error</em> yaitu siswa kurang teliti dalam membaca soal (b) <em>Comprehension error </em>yaitu siswa tidak memahami apa yang diketahui dalam soal. (c) <em>Tran</em><em>s</em><em>formation error </em>yaitu siswa salah dalam menggunakan rumus, siswa salah merubah satuan. (d) <em>Process skill error </em>yaitu siswa salah mengoperasikan perhitungan. (e) <em>Encoding error </em>yaitu siswa salah menuliskan jawaban akhir.</p>
Pengaruh Model Problem Based Learning (PBL) Berbantuan Video Pembelajaran Terhadap Kemampuan Literasi Sains Pada Pembelajaran Ipas Siswa Kelas IV SDN Gugus XIV Kota Bengkulu
Authors: Sari Lidia Puspita , Dalifa Dalifa , Agusdianita Neza , Noperman Feri , Yusnia Yusnia 
Published: January 2025

<p>Penelitian ini bertujuan untuk mengetahui pengaruh model <em>Problem Based Learning</em> (PBL) berbantuan video pembelajaran terhadap kemampuan literasi sains pada pembelajaran IPAS siswa kelas IV SD Negeri gugus XIV Kota Bengkulu. Jenis penelitian ini adalah penelitian kuantitatif dengan metode eksperimen semu. Desain penelitian yang digunakan adalah <em>The Matching Only Pretest-Posttest Control Group Design</em>. Populasi pada penelitian ini adalah SDN Gugus XIV Kota Bengkulu, dengan sampel penelitian siswa kelas IV A SDN 42 Kota Bengkulu dan siswa kelas IV B SDN 45 Kota Bengkulu. Instrumen penelitian menggunakan tes berupa <em>pretest </em>dan <em>posttest</em> dalam bentuk soal uraian sebanyak 6 soal. Teknik analisis data yang digunakan adalah analisis kuantitatif dengan statistik deskriptif, analisis uji prasyarat dan uji hipotesis. Berdasarkan hasil penelitian ini diperoleh nilai thitung &gt; ttabel yaitu (4,097 &gt; 1,680) dan nilai sig. (2-tailed) adalah 0,000 &lt; 0,05 , artinya Ha diterima. Nilai signifikansi uji-t tersebut membuktikan hipotesis penelitian bahwa terdapat pengaruh yang signifikan penggunaan model PBL Berbantuan Video Pembelajaran terhadap Kemampuan Literasi Sains pada pembelajaran IPAS siswa kelas IV SDN Gugus XIV Kota Bengkulu.</p>
Pengaruh Metode Samiyah Syafawiyah terhadap Keterampilan Menulis Insya’ Bahasa Arab di Pondok Pesantren Baitul Qur’an Darussalam Sidoarjo.
Authors: Jihady Muhammad Ihsan , Anwar Najih 
Published: January 2025

<p>Penelitian ini menginvestigasi pengaruh Metode Samiyah Syafawiyah terhadap kemampuan menulis Insya' Bahasa Arab di Pondok Pesantren Baitul Qur’an Darussalam Sidoarjo. Dengan menggunakan pendekatan kuantitatif dan rancangan Pre-Eksperimental One Group Pretest-Posttest Design, data dikumpulkan dari 21 santri sebelum dan setelah perlakuan. Hasil analisis menunjukkan bahwa metode tersebut memiliki pengaruh yang signifikan terhadap peningkatan kemampuan menulis Insya', dengan rata-rata posttest yang lebih tinggi dari pretest (69.76 vs 59.05). Uji statistik Paired Sample T Test menunjukkan nilai signifikansi yang rendah (0.000 &lt; 0.05), mengindikasikan adanya hubungan antara penggunaan metode tersebut dan peningkatan kemampuan menulis. Kesimpulannya, Metode Samiyah Syafawiyah efektif dalam meningkatkan keterampilan menulis Insya' Bahasa Arab di lingkungan pendidikan Pondok Pesantren.</p><p> </p>
The Risk of Postoperative Periprosthetic Femoral Fracture After Total Hip Arthroplasty Depends More on Stem Design Than Cement Use
Authors: Lamb J.N. , West R.M. , Relton S.D. , Wilkinson J.M. , Pandit H.G. 
Published: January 2025

Background:
In this study, we estimated the risk of surgically treated postoperative periprosthetic femoral fractures (POPFFs) associated with femoral implants frequently used for total hip arthroplasty (THA).

Methods:
In this cohort study of patients who underwent primary THA in England between January 1, 2004, and December 31, 2020, POPFFs were identified from prospectively collected revision records and national hospital records. POPFF incidence rates, adjusting for potential confounders, were estimated for common stems. Subgroup analyses were performed for patients >70 years of age, with non-osteoarthritic indications, and with femoral neck fracture.

Results:
POPFFs occurred in 0.6% (5,100) of 809,832 cases during a median follow-up of 6.5 years (interquartile range [IQR], 3.9 to 9.6 years). After cemented stem implantation, the majority of POPFFs were treated with fixation. Adjusted prosthesis time incidence rates (PTIRs) for POPFFs varied by stem design, regardless of cement fixation. Cemented composite beam (CB) stems demonstrated the lowest risk of POPFF. Collared cementless stems had an equivalent or lower rate of POPFF compared with the current gold standard of a polished taper slip cemented stem.

Conclusions:
Cemented CB stems were associated with the lowest POPFF risk, and some cementless stem designs outperformed modern cemented stem designs. Stem design was strongly associated with POPFF risk, regardless of the presence of cement. Surgeons, policymakers, and patients should consider these findings when considering femoral implants in those most at risk for POPFF.

Level of Evidence:
Prognostic Level III. See Instructions for Authors for a complete description of levels of evidence.
CO2 Mobility Control by Foam at Bati Raman Heavy Oilfield - Laboratory Tests on Mobility Reduction and Oil Recovery
Authors: Topgüder N.N. Senol 
Published: January 2025

Abstract
A series of laboratory tests were performed to investigate the applicability of foam as a mobility control process at the ongoing Ban Raman CO2 injection project. The tests consisted of the following steps : selection of the suitable surfactant by preliminary screening and foam texture tests, adsorption, mobility reduction and oil recovery. The suitable surfactant, Gafoam AD, was tested in mobility reduction by pre generated foam and in-situ foam generation by either alternating slugs or simultaneous injection. In alternating slugs injection mode, the mobility reduction effect of foam was not very distinguished. However, with pregenerated foam injection and especially in simultaneous injection case, significant reduction in mobility was observed. Regardless of foam quality or injection rate; simultaneous injection of surfactant solution and CO2 gas, showed good performance in CO2 mobility reduction. Therefore, in oil recovery tests, only simultaneous injection mode was employed. Oil recovery with foam was about 53-60 per cent of OIP where by plain CO2 injection only 25-30 per cent of OIP was recovered.
Evolution of livestock production systems and impact on infectious disease resilience: the Swiss example
Authors: Galli Francesco , Perret-Gentil Saskia , Champetier Antoine , Lüchinger Rita , Harisberger Myriam , Kuntzer Thibault , Rieder Stefan , Nathues Christina , Vidondo Beatriz , Lentz Hartmut , Belik Vitaly , Dürr Salome 
Published: January 2025

Abstract

Livestock production systems are complex and evolve over time, affecting their adaptability to economic, political, and disease-related changes. In Europe, disease resilience is crucial due to threats like the African swine fever virus, which jeopardizes pork production stability. The European Union identifies farm production type as a key risk factor for disease spread, making it important to track changes in farm production types to assess disease risk. However, detailed production type data is often lacking in national databases. For Swiss pig farms, we used prediction and clustering algorithms to classify 9’687 − 11’247 trading farms between 2014 and 2019 by one of eleven production types. We then analyzed the pig trade network and stratified farm centrality measures (ICC and OCC) by production type. We found that 145 farms belonging to three production types have substantially higher ICC and OCC than other farms, suggesting that they could be the target of disease surveillance programs. Our predictions until 2025 show an increase both in overall pig trade network connectivity and in proportion of production types with high ICC and OCC, indicating that the structural changes in the Swiss pig production system may increase infectious disease exposure over time.
Nuclei-specific abnormalities of amygdala functional connectivity and their changes after multiple types of treatments for depression: a multicenter MRI study
Authors: Oishi Naoya , Ishikawa Yuzuki , Kyuragi Yusuke , Hatakoshi Momoko , Hirano Jinichi , Noda Takamasa , Yoshihara Yujiro , Igarashi Hiroyuki , Takahashi Kento , Murakami Shingo , Kanno Hiroyuki , Takamiya Akihiro , Matsumoto Junya , Kodaka Fumitoshi , Nakagome Kazuyuki , Mimura Masaru , Murai Toshiya , Suwa Taro 
Published: January 2025

Abstract

Exploring the neurobiological effects of various treatments for depression is pivotal in elucidating shared and unique mechanisms of action that may explain commonalities and differences in treatment outcomes. The amygdala, consisting of subdivisions with distinct roles in emotional processing, is thought to be implicated in the pathophysiology of depression. However, how various treatments alter nuclei-specific resting-state functional connectivity (rs-FC) of the amygdala remains unclear. Here, we hypothesized that treatments restore nuclei-specific rs-FC abnormalities of the amygdala, with shared and unique changes. To test this hypothesis, this multicenter observational study analyzed functional MRI data of patients with depression (N = 187) and healthy controls (N = 113). Patients were scheduled to undergo either cognitive behavioral therapy (CBT; N = 63), medication therapy (N = 43), electroconvulsive therapy (ECT; N = 32), or transcranial magnetic stimulation (TMS; N = 26). Nine amygdala subregions were delineated using the FreeSurfer segmentation module. To enhance interpretability and reliability, these subregions were further clustered by applying k-means + + clustering to resting-state functional MRI time courses, resulting in three clusters referred to as the basolateral (BL), basomedial (BM), and centromedial (CM) subdivisions based on their anatomical locations. At baseline, the BL and BM subdivisions of patients with depression exhibited hyperconnectivity with the mediodorsal thalamus (MDTH), periaqueductal gray, perigenual anterior cingulate cortex, dorsal raphe nucleus, and dorsomedial prefrontal cortex. Following treatment, there were no shared rs-FC changes across treatment types; however, BL-MDTH connectivity decreased to the level of healthy controls following ECT. These results demonstrate that ECT-specific restoration of rs-FC exists while multiple treatments do not share common rs-FC changes in the amygdala.
Machine Learning Modeling for Multi-order Human Visual Motion Processing
Authors: Nishida Shin'ya , Sun Zitang , Chen Yen-Ju , Yang Yung-hao , Li Yuan 
Published: January 2025

Abstract

Our research aims to develop machines that learn to perceive visual motion as do humans. While recent advances in computer vision (CV) have enabled DNN-based models to accurately estimate optical flow in naturalistic images, a significant disparity remains between CV models and the biological visual system in both architecture and behavior. This disparity includes humans' ability to perceive the motion of higher-order image features (second-order motion), which many CV models fail to capture because of their reliance on the intensity conservation law. Our model architecture mimics the cortical V1-MT motion processing pathway, utilizing a trainable motion energy sensor bank and a recurrent graph network. Supervised learning employing diverse naturalistic videos allows the model to replicate psychophysical and physiological findings about first-order (luminance-based) motion perception. For second-order motion, inspired by neuroscientific findings, the model includes an additional sensing pathway with nonlinear preprocessing before motion energy sensing, implemented using a simple multilayer 3D CNN block. When exploring how the brain acquired the ability to perceive second-order motion in natural environments, in which pure second-order signals are rare, we hypothesized that second-order mechanisms were critical when estimating robust object motion amidst optical fluctuations, such as highlights on glossy surfaces. We trained our dual-pathway model on novel motion datasets with varying material properties of moving objects. We found that training to estimate object motion from non-Lambertian materials naturally endowed the model with the capacity to perceive second-order motion, as can humans. The resulting model effectively aligns with biological systems while generalizing to both first- and second-order motion phenomena in natural scenes.
Southern Ocean CO2 outgassing and nutrient load reduced by a well-ventilated glacial North Pacific
Authors: Shankle Madison , MacGilchrist Graeme , Gray William , de Lavergne Casimir , Menviel Laurie , Burke Andrea , Rae James 
Published: January 2025

Abstract

The biogeochemistry of Southern Ocean surface waters has global impacts on nutrient distributions, the carbon cycle, and climate, motivating study of its underlying controls and changes under altered climate states. Today, poorly-ventilated North Pacific waters supply the majority of carbon and nutrients upwelling in the Southern Ocean, outpacing the rate of biological carbon assimilation and fueling CO2 outgassing. A means of reducing this carbon/nutrient supply is central to explaining the improved biological pump efficiency evidenced in paleo-proxy reconstructions and invoked in theories for glacial CO2 change. Past studies predominantly attribute reduced glacial carbon/nutrient load of Southern Ocean surface waters to local physical processes (e.g., reduced wind-driven upwelling or enhanced stratification). Here we propose a complementary mechanism in which the carbon/nutrient load of the source waters feeding the Southern Ocean surface is reduced remotely, prior to being upwelled. Comparing glacial North Pacific and Southern Ocean proxy records, alongside results from 3 different Earth System Models, we show that improved ventilation of the glacial North Pacific directly reduces carbon/nutrient-delivery to and CO2 outgassing in the Southern Ocean surface. This highlights a novel interhemispheric influence on the biogeochemical state of the Southern Ocean, which may play a key role in glacial CO2 change.
The Utility of Serum Neuropilin 1 as a Diagnostic Marker for Hepatocellular Carcinoma in Egyptian Cirrhotic Patients Running Title: Serum Neuropilin 1 as a Diagnostic Marker for Hepatocellular Carcinoma in Egyptian Cirrhotic Patients
Authors: Assem Nourhan , Ahmed Osama Ashraf , Mohamed Nada Mohamed Hassan , Mahmoud Kareem Ahmed 
Published: January 2025

Abstract

Background: Incidence of Hepatocellular carcinoma (HCC) has increased over the past few decades to become the most common primary hepatic malignancy. Most patients with HCC have advanced unresectable disease, resulting in limited treatment options with curative intent and poor survival outlooks.
Results: In this study on Egyptian patients, hepatocellular carcinoma (HCC) primarily occurred in the sixth decade of life, often alongside liver cirrhosis. No significant gender or smoking differences were found between HCC and cirrhotic groups, suggesting smoking isn't a major HCC risk factor. Diabetes mellitus (DM) and hypertension (HTN) were more common in HCC patients, reflecting their roles in cirrhosis and HCC development. Serum alpha-fetoprotein (AFP) levels were significantly higher in HCC patients. Neuropilin-1, a novel marker, showed a significant increase in HCC patients compared to cirrhotic ones, with a strong correlation to liver function markers (AST, ALT, AFP, albumin) and Barcelona and Child scores. Neuropilin-1 demonstrated higher sensitivity (96.67%) and specificity (80%) for HCC detection compared to AFP, highlighting its potential as a superior biomarker for diagnosing HCC.
Conclusion: Serum neuropilin 1 level was significantly higher in patients with HCC regardless presence of combined conditions as DM and HTN or viral markers and mildly elevated in patients with liver cirrhosis compared to HCC group. Neuropilin 1 is more sensitive and more specific than AFP. Using neuropilin 1 will improve the diagnostic field and can help in early detection of HCC in surveillance programs together with AFP.
Potential for expanding sorghum production in Europe in the face of climate change
Authors: Davoudkhani Mohsen , Guilpart Nicolas , Makowski David , Viovy Nicolas , Ciais Philippe , Lauerwald Ronny 
Published: January 2025

Abstract

Today, sorghum is a minor crop in Europe cultivated on only ~0.1% of the cropland area. Nonetheless, sorghum is of growing interest due to its high heat tolerance compared to other crops and better adaptation to future hot and dry summers. In this study, we investigated the feasibility of expanding sorghum cultivation in Europe under current and future climatic conditions. We also explored the possibility of replacing maize with locally-produced sorghum for feeding livestock. To this end, we developed a machine-learning model that predicts sorghum yields from high-resolution climate data. The model was trained on historical sorghum yield data collected at the county level in France, Italy, Spain, and the USA. Then, we used the model to predict sorghum yields for current and future climate conditions, following different climate change scenarios. In almost all scenarios, sorghum yields decreased by up to -1.5 t ha-1 in the southern part of Europe but increased substantially by up to + 3 t ha-1 in the northern part of Europe by end-of-century. We found that at least 90% of maize currently used to feed livestock could be replaced by sorghum in Europe if grown in one out of three years. These results provide valuable information for improving feed security in Europe in the face of climate change.