bluuebunny/crossref_metadata_2025_split huggingface dataset:
A case report of near-missed heat stroke
Authors: Yeoh Cheng Wooi , Law Wan Chung 
Published: December 2023

Rationale:
Heat-related illnesses have protean manifestations that can mimic other life-threatening conditions. The diagnosis of heat stroke requires a high index of suspicion if the patient has been exposed to a high-temperature environment. Central nervous system dysfunction is a cardinal feature. Strict adherence to temperature criteria can potentially lead to misdiagnosis.

Patient concerns:
A 37-year-old construction worker was brought in by his wife and coworker due to a sudden loss of consciousness while resting after completing his work.

Diagnoses:
Due to challenges faced during the coronavirus disease 2019 pandemic, as well as language barriers, a detailed history from the coworker who witnessed the patient’s altered sensorium was not available. He was initially suspected of having encephalitis and brainstem stroke. However, subsequent investigations revealed multiorgan dysfunction with a normal brain computed tomography and cerebral computed tomography angiogram. In view of the multiple risk factors for heat stroke, pupillary constriction, and urine color suggestive of rhabdomyolysis, a diagnosis of heat stroke was made.

Interventions:
Despite delayed diagnosis, the patient’s multiorgan dysfunction recovered within days with basic supportive care.

Outcomes:
There were no noticeable complications on follow-up 14 months later.

Lessons:
Heat stroke can be easily confused with other neurological pathologies, particularly if no history can be obtained from the patient or informant. When approaching a comatose patient, we propose that serum creatinine kinase should be considered as an initial biochemical screening test.
Upside-down stomach in paraesophageal hernia: A case report
Authors: Zhu Xiuliang , Hu Chengyu , Gong Weihua 
Published: December 2023

Rationale:
Paraesophageal hernias, accounting for a mere 5% to 10% of all hiatal hernias, occasionally present an exceedingly uncommon yet gravely consequential complication characterized by the inversion of the stomach. Delving into the clinical manifestations and optimal therapeutic approaches for patients afflicted by this condition merits substantial exploration.

Patient concerns:
A 60-year-old man was referred to our hospital with acute onset of severe epigastric pain, abdominal distension, and vomiting. A chest radiograph unveiled an elevated left diaphragmatic dome accompanied by a pronounced rightward shift of the mediastinum. Subsequent abdominal computed tomography imaging delineated the migration of the stomach, spleen, and colon into the left hemithorax, facilitated by a significant diaphragmatic defect.

Diagnoses:
The diagnosis of a giant paraesophageal hernia with complete gastric inversion was established through a comprehensive evaluation of the patient’s clinical manifestations and imaging findings.

Interventions:
Surgical intervention was performed on the patient. During the procedure, a left diaphragmatic defect measuring approximately 10 × 8 cm was identified and meticulously repositioned, followed by the repair of the diaphragmatic hernia. The herniated contents comprised the pancreas, stomach, spleen, a segment of the colon, and a portion of the greater omentum.

Outcomes:
The patient experienced a smooth postoperative recuperation and was discharged 12 days following the surgical procedure. Subsequently, during a 7-month follow-up period, the patient continued to exhibit favorable progress and recovery.

Lessons:
Paraesophageal hernias are rare, and the presence of an inverted stomach in a giant paraesophageal hernia is exceptionally uncommon. Clinical presentation lacks distinct features and can lead to misdiagnosis. This case emphasizes the importance of timely surgical intervention guided by imaging, offering valuable clinical insights.
Lateral Lymph Node Dissection for Locally Advanced Rectal Carcinoma: A Step-by-Step Description of Surgical Anatomical Planes During Cadaveric Dissection and Minimally Invasive Surgery
Authors: İsmail Erkin , Kutlu Burak , Acar Halil İbrahim , Yörübulut Mehmet , Akkoca Muzaffer , Kocaay Akin Firat , Elhan Atilla , Kuzu Mehmet Ayhan 
Published: December 2023

Purpose:
Total mesorectal excision (TME) is accepted as gold standard method in rectal cancer globally. But there is no standard for lateral lymph nodes. Combination of neoadjuvant treatment plus lateral lymph node dissection (LLND) in select patients might be a promising method. Our purpose is to describe the anatomic landmarks of LLND on cadavers and minimally invasive surgery.

Materials and Methods:
Local advanced rectal cancer and lateral lymph node (LLN) metastasis are accepted as an indication of neoadjuvant treatment. LLND was performed according to preoperative imaging after radiochemotherapy.

Results:
Twenty-eight (10.5%) of 267 patients with rectal cancer who had suspected lateral lymph node metastasis (LLNM) with magnetic resonance imaging (MRI) underwent LLND in addition to TME after neoadjuvant chemoradiotherapy. Eight of them had LLNM. Three patients had bilateral LLND and only 1 had LLNM. The median number of harvested lymph nodes was 6. The rates of LLNM increased with the presence of poor prognosis markers. One regional and 1 distant recurrence were detected in patients who had no LLN metastasis compared with2 regional and 4 distant recurrences in the LLN-positive group.

Conclusions:
Local advanced rectal cancer cases may benefit from LLND, but it does not appear to have an effect on overall survival. There is no consensus whether size and/or morphologic criteria in MRI are the ideal guide for LLND.
Thalamic nuclei in patients with chronic facial pain: gray matter volume patterns before and after surgery
Authors: Anton Pashkov , Elena Filimonova , Boris Zaitsev , Azniv Martirosyan , Galina Moysak , Jamil Rzaev 
Published: December 2023

AbstractTrigeminal neuralgia is a prevalent chronic pain disorder characterized by recurring episodes of intense facial pain, which significantly impairs patients’ quality of life. MRI-based biomarkers have consistently demonstrated their ability to predict pain intensity and treatment outcomes. However, most studies have primarily focused on the trigeminal system, paying less attention to the extensive neural reorganization that occurs throughout the brain in response to chronic pain. In this study, we aimed to examine the thalamus, a key brain structure involved in information processing, and provide a detailed perspective on thalamic remodeling in response to chronic pain at the level of individual thalamic nuclei. We analyzed a sample of 62 patients with primary trigeminal neuralgia undergoing surgical treatment, along with 28 healthy participants. Our results revealed significant gray matter volume changes in thalamic nuclei among patients with trigeminal neuralgia. Notably, the intralaminar nuclei (centromedian/parafascicular) and nuclei associated with visual and auditory signal processing (lateral and medial geniculate bodies) exhibited significant alterations, contrasting with the ventral group nuclei involved in nociceptive processing. Additionally, we found no substantial volume increase in any of the studied nuclei following successful surgical intervention 6 months later. The volumes of thalamic nuclei were negatively correlated with pain intensity and disease duration. The findings obtained in this study, albeit preliminary, have promising clinical implications as they unveil previously unknown facets of chronic pain development.PerspectiveThe study examined alterations in gray matter volume within the thalamus of patients diagnosed with trigeminal neuralgia at the level of specific nuclei. The most significant changes were observed in the lateral and medial geniculate bodies, along with the pulvinar nuclei.HighlightsA detailed investigation of the thalamic nuclei in patients suffering from primary trigeminal neuralgia (TN) has been carried out for the first time.Patients with TN showed a significant gray matter volume decrease in intralaminar, sensory and associative nuclei.Following successful surgery, there was no observed increase in the volume of the investigated nuclei.
Status epilepticusduring neurodevelopment increases seizure susceptibility: a model study in zebrafish (Danio rerio)
Authors: Mazon Samara Cristina , Mendes Ellen Jaqueline , Sachett Adrieli , Bertoncello Kanandra Taisa , Marsaro Isabella Bodanese , Daniel Carla Fatima , de Miranda Fernanda Barros , Hort Mariana Appel , Oliveira J. Vladimir , Piato Angelo , Alves Lima-Rezende Cássia , Herrmann Ana Paula , Müller Liz Girardi , Siebel Anna Maria 
Published: December 2023

AbstractEpilepsy is among the most common neurological diseases, affecting more than 50 million people worldwide. Unfortunately, one-third of people with epilepsy fail to respond to any current treatment and present a decreased quality of life. Nevertheless, different studies suggest that epilepsies acquired from an initial insult asstatus epilepticus(SE) followed byepileptogenesiscan be prevented. Therefore, it is necessary to establish animal models ofepileptogenesisinduced by SE. Thus, here we proposed an animal model ofepileptogenesistriggered by SE that occurred during the neurodevelopment of zebrafish (Danio rerio). Zebrafish larvae at the 7thday post-fertilization (dpf) were randomly assigned to two experimental groups. One group was exposed to embryo medium. The other group was exposed to pentylenetetrazol (15 mM PTZ) to induce SE. At the 8thdpf, each larva was subjected to the open tank test (OTT) to analyze locomotion and behavioral parameters. After the OTT, each initial group was divided into two groups: animals maintained in embryo medium and animals exposed to PTZ (3 mM), and the susceptibility to PTZ-induced seizure-like behavior was analyzed. Data showed that animals submitted to SE on the 7thdpf showed altered locomotion and behavior 24 hours later. Interestingly, zebrafish larvae submitted to SE on the 7thdpf showed decreased latency to reach seizure-like behavioral stages when exposed to a low concentration of PTZ on the 8thdpf. Concluding, our results show that SE during neurodevelopment increases the susceptibility of zebrafish larvae to present PTZ-induced seizure-like behavior. Our study contributes to the establishment of a model ofepileptogenesisin developing zebrafish. Finally, the next step is to improve this model by characterizing molecular, biochemical and physiological markers.
Accounting and neoliberal responsibilisation: a case study on the Australian National Disability Insurance Scheme
Authors: Nikidehaghani Mona 
Published: December 2023

PurposeThis paper aims to explore how accounting is fostering neoliberal citizenship through the participants of Australia’s National Disability Insurance Scheme (NDIS). More specifically, this paper aims to understand how accounting discourse and the management accounting technique of budgeting, when intertwined with automated administrative processes of the NDIS, are giving rise to a pastoral form of power that directs people’s behaviour toward certain ends.Design/methodology/approachPublicly available data has been crafted into an autoethnographic case study of one fictitious person’s experiences with the NDIS – Mina. Mina is an amalgam created from material submitted to the Joint Parliamentary Standing Committee on the NDIS. Mina’s experiences are then analysed through the lens of Foucault’s concept of pastoral power to explore how accounting has contributed to marketising and digitising public disability services.FindingsAccounting rhetoric appears to be a central part of rationalising the decision to shift to individualised disability funding. Those receiving payments are treated as self-governable, financially responsible subjects and are therefore expected to have knowledge of management accounting techniques and budgeting. However, NDIS’s strong reliance on the accounting concepts of funds, budgets, cost and price is limiting people’s autonomy and subjecting them to intervention and control.Originality/valueThis paper addresses calls to explore the interplay between accounting and current disability policies. The analysis shows that incorporating accounting into the NDIS’s algorithms serves to conceal the underlying ideology of the programs, subtly driving behaviours towards neoliberal objectives. Further, this research extends the Foucauldian accounting literature by revealing the contribution of accounting to reinforcing the authority of digital pastors in contemporary times.
Digitalization of operations and supply chains: Insights from survey and case studies
Authors: Baycik N. Orkun , Gowda Shimon 
Published: December 2023

PurposeThis article aims to understand where industry is in terms of digitalizing their operations, what features of this transformation are essential for practitioners, and what barriers they are facing during their journey. In addition, the authors aim to provide recommendations for organization to start their digital transformation.Design/methodology/approachThrough literature review, the authors summarize the emerging tools and technologies in operations and supply chains to inform the practitioners. Then, the authors use surveys conducted on 183 operations and supply chain professionals, and use statistical tools to examine the association between variables of the data set. The authors present real-life case studies to explain important steps of a digital transformation project.FindingsThe survey results indicate that real-time monitoring and data analytics are viewed as the most important and needed tools for organizations. High cost, lack of stakeholder buy-in and lack of successful business use cases are major barriers for companies when starting a digital transformation.Practical implicationsThe authors provide recommendations for practitioners based on the survey responses, and outline that starting small, focusing on stakeholder buy-in and implementation of software are the three key steps for a successful transformation journey.Originality/valueMain contributions of this article are to understand practitioner perspectives in digitalization and provide guidelines for organizations to follow when transforming their operations. This research closes the gap between academic research and practice by collaborating with operations and supply chain professionals.
“What is a wave but 1000 drops working together?”: The role of public libraries in addressing LGBTQIA+ health information disparities
Authors: Kitzie Vanessa , Vera A. Nick , Lookingbill Valerie , Wagner Travis L. 
Published: December 2023

PurposeThis paper presents results from a participatory action research study with 46 LGBTQIA+ community leaders and 60 library workers who participated in four community forums at public libraries across the US. The forums identified barriers to LGBTQIA+ communities addressing their health questions and concerns and explored strategies for public libraries to tackle them.Design/methodology/approachForums followed the World Café format to facilitate collaborative knowledge development and promote participant-led change. Data sources included collaborative notes taken by participants and observational researcher notes. Data analysis consisted of emic/etic qualitative coding.FindingsResults revealed that barriers experienced by LGBTQIA+ communities are structurally and socially entrenched and require systematic changes. Public libraries must expand their strategies beyond collection development and one-off programming to meet these requirements. Suggested strategies include outreach and community engagement and mutual aid initiatives characterized by explicit advocacy for LGBTQIA+ communities and community organizing approaches.Research limitations/implicationsLimitations include the sample's lack of racial diversity and the gap in the data collection period between forums due to COVID-19. Public libraries can readily adopt strategies overviewed in this paper for LGBTQIA+ health promotion.Originality/valueThis research used a unique methodology within the Library and Information Science (LIS) field to engage LGBTQIA+ community leaders and library workers in conversations about how public libraries can contribute to LGBTQIA+ health promotion. Prior research has often captured these perspectives separately. Uniting the groups facilitated understanding of each other's strengths and challenges, identifying strategies more relevant than asking either group alone.
Generative AI and generative libraries and beyond –conference report on IFLA and IFA
Authors: Kesselman Martin A. , Esquivel Wilson 
Published: December 2023

Purpose
This study aims to provide insight of how conference sessions and poster sessions are relevant to libraries.

Design/methodology/approach
Recently attended IFLA and Internationale Funkaussteilung (IFA) and focused the conference report on generative artificial intelligence (AI).

Findings
Disappointed in the IFLA and IFA conferences and instead find that the email newsletter from Shelly Palmer is much better in keeping up with exponential growth in ChatGPT and other generative AI tools.

Research limitations/implications
This study may provide ideas for libraries to experiment with generative AI tools.

Originality Value
This study is an original report by the authors. All photos were taken by the authors except for a table from the email newsletter of Shelly Palmer, which was included by him from another source.
TPI1 promotes MAPK/ERK‐induced EMT, cell migration and invasion in lung adenocarcinoma
Authors: Li Yu , Pan Bin , Zhang Feiyang , Jia Xinyu , Zhu Xinyu , Tong Xin , Zhao Jun , Li Chang 
Published: December 2023

AbstractBackgroundTriosephosphate isomerase 1 (TPI1), as a widely involved glycolytic enzyme, plays a significant role in glucose metabolism and is highly expressed in various tumors. However, its role in lung adenocarcinoma (LUAD) remains incompletely understood.MethodsThrough bioinformatic analysis, we identified a positive association between high expression of TPI1 and metastasis in LUAD. Western blot, RT‐qPCR, wound healing assays and transwell experiments, were employed to investigate potential mechanisms.ResultsIn this study, bioinformatic analysis showed that high expression of TPI1 was associated with poor prognosis in LUAD patients. We examined the expression of TPI1 in 29 paired LUAD tissues and found that TPI1 expression was higher in LUAD tissues than in paired adjacent noncancerous tissues. Meanwhile, overexpression of TPI1 promoted the epithelial‐mesenchymal transition (EMT) process in LUAD cells, while silencing TPI1 weakened the EMT process. Furthermore, TPI1 was shown to regulate EMT through the MAPK/ERK signaling pathway.ConclusionTPI1 promotes LUAD metastasis by activating the MAPK/ERK signaling pathway.
Genetic context drives age‐related disparities in synaptic maintenance and structure across cortical and hippocampal neuronal circuits
Authors: Heuer Sarah E. , Nickerson Emily W. , Howell Gareth R. , Bloss Erik B. 
Published: December 2023

AbstractThe disconnection of neuronal circuitry through synaptic loss is presumed to be a major driver of age‐related cognitive decline. Age‐related cognitive decline is heterogeneous, yet whether genetic mechanisms differentiate successful from unsuccessful cognitive decline through maintenance or vulnerability of synaptic connections remains unknown. Previous work using rodent and primate models leveraged various techniques to imply that age‐related synaptic loss is widespread on pyramidal cells in prefrontal cortex (PFC) circuits but absent on those in area CA1 of the hippocampus. Here, we examined the effect of aging on synapses on projection neurons forming a hippocampal‐cortico‐thalamic circuit important for spatial working memory tasks from two genetically distinct mouse strains that exhibit susceptibility (C57BL/6J) or resistance (PWK/PhJ) to cognitive decline during aging. Across both strains, synapse density on CA1‐to‐PFC projection neurons appeared completely intact with age. In contrast, we found synapse loss on PFC‐to‐nucleus reuniens (RE) projection neurons from aged C57BL/6J but not PWK/PhJ mice. Moreover, synapses from aged PWK/PhJ mice but not from C57BL/6J exhibited altered morphologies that suggest increased efficiency to drive depolarization in the parent dendrite. Our findings suggest resistance to age‐related cognitive decline results in part by age‐related synaptic adaptations, and identification of these mechanisms in PWK/PhJ mice could uncover new therapeutic targets for promoting successful cognitive aging and extending human health span.
A multi‐scale synthesis of mousedeer habitat associations in Southeast Asia reveals declining abundance but few extirpations in fragments and edges
Authors: Mendes Calebe P. , Liu Xiaohan , Amir Zachary , Moore Jonathan H. , Luskin Matthew Scott 
Published: December 2023

AbstractHabitat loss and fragmentation profoundly impact Southeast Asian rainforest biodiversity and ecosystem functioning. While many larger herbivores are hunted and area‐demanding apex predators are lost from degraded forests (logged forests, forest fragments and forest edges), smaller herbivore species may be comparatively resilient or even benefit from a release from competition and predation in degraded forests. Mousedeer (or chevrotains) in the Tragulus genus are some of the world's smallest ungulates (1.5–4.5 kg) and are widespread in Southeast Asia. We evaluated mousedeer habitat associations at three spatial scales. At the regional scale, presence‐only species distribution modelling suggested mousedeer are negatively associated with aridity and elevation. At the landscape scale, variation capture rates among 186 published camera trapping studies suggested mousedeer are negatively associated with forest degradation and elevation. At the local scale (within landscapes), mousedeer abundance sampled with 1218 cameras at 10 landscapes and analysed with hierarchical abundance modelling suggested mousedeer are negatively associated with humans and elevation. Mousedeer diel activity patterns shifted towards increased nocturnality in degraded forests, possibly to avoid interactions with diurnal humans. Taken together, mousedeer prefer wet lowland forests and they persist – but decline – in degraded habitats and near humans. One exception was degraded forest fragments of Singapore where mousedeer are very abundant, likely due to the absence of hunting and predators. Our results emphasize that small herbivores persisting in fragmented rainforests decline relative to intact forests and thus are unlikely to be experiencing significant release from competition or predation. They also differ from small omnivorous generalists who experience beneficial foraging opportunities at edges. In degraded forests where larger wildlife has been lost, even low densities of small herbivores may perpetuate important ecological interactions such as herbivory, seed dispersal, or as prey for remaining predators.