bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concentration of Tetrabromobisphenol-A in fish: systematic review and meta-analysis and probabilistic health risk assessment
Authors: Mahmudiono Trias , Fakhri Yadolah , Ranaei Vahid , Pilevar Zahra , Limam Intissar , Sahlabadi Fatemeh , Rezaeiarshad Negin , Torabbeigi Marzieh , Jalali Samaneh 
Published: February 2024

Abstract
Tetrabromobisphenol A (TBBP-A) is an emerging pollutant that enters water resources and affects various marine organisms, such as fish. Consequently, numerous studies globally investigated TBBP-A concentrations in fish fillets of the current study were meta-analyze concentration of TBBP-A in fish fillets and estimate the associated health risks for consumers. The search encompassed international databases, including Science Direct, PubMed, Scopus, Embase, and Web of Science from January 1, 2005, to July 20, 2023. The ranking of countries based on the pooled (Mean) concentration of TBBP-A in fish was as follows: China (1.157 µg/kg-ww) > Czech Republic (1.027 µg/kg-ww) > France (0.500 µg/kg-ww) ∼ Switzerland (0.500 µg/kg-ww) > Netherlands (0.405 µg/kg-ww) > Germany (0.33 µg/kg-ww) > Sweden (0.165 µg/kg-ww)>UK (0.078 µg/kg-ww) > Belgium (0.065 µg/kg-ww) > South Korea (0.013 µg/kg-ww) ∼ Japan (0.013 µg/kg-ww) > Ireland (0.005 µg/kg-ww). The risk assessment showed that the carcinogenic and non-carcinogenic risks of TBBP-A in China and France are higher compared to other countries; however, within all countries, these risks were found to be within acceptable limits.
Biosensors and its diverse applications in healthcare systems
Authors: Paramasivam Selvakumar , Palanisamy Satheesh Kumar , Cinthaikinian Selvamurugan , Palanisamy Vigneshkumar , Mariappan Raja , Selvakumar Palani Kishore 
Published: February 2024

Abstract
This paper provides a thorough analysis of recent developments in radio frequency identification (RFID)-based biosensors and their uses in the medical industry. The most recent and cutting-edge technologies used in RFID sensors, as well as their operational procedures in the medical industry, are the main focus of this article. The most effective design methodology for RFID biosensors is determined by evaluating various design methodologies. The present state of the art technologies in this domain are also analyzed and discussed. This paper aims to support researchers in the development of inexpensive and widely available RFID-based biosensors that can improve medical and healthcare outcomes. The use of RFID biosensors in contemporary medical applications has demonstrated significant promise for enhancing patient care and facilitating the early diagnosis of a number of diseases. It is anticipated that RFID biosensor technology will maintain to play a significant role in the development of the medical field as it undergoes further development.
Analiza sytuacyjna w badaniach codzienności miejskiej
Authors: Pawlik Jacek Jan 
Published: February 2024

W niniejszym artykule zostanie przedstawione zastosowanie podejścia sytuacyjnego do badań społeczności miejskich. Podejście to jest szczególnie użyteczne w przypadku badań życia codziennego i ściśle łączy się z analizą sieci. Po przedstawieniu założeń teoretycznych tego podejścia, autor analizuje trzy przypadki sytuacji pochodzące z jego badań terenowych prowadzonych w Lomé, stolicy Togo. Okazuje się, że analiza sytuacyjna w połączeniu z analizą strukturalną pozwala na uzyskanie adekwatnego obrazu życia w mieście.
Wielokulturowa Łódź jako miejsce pamięci po 1945 roku – zmienność i różnorodność
Authors: Kucner Monika 
Published: February 2024

W XIX i XX w. Łódź była miejscem, w którym spotkały się różne kultury, religie, języki i narodowości. Impulsem dla powstania tego wielonarodowego tygla był przemysł tekstylny, który przyciągnął osadników z różnych części Europy. W przeciągu kilku dziesięcioleci z małego miasta Łódź rozwinęła się w wielką metropolię, której wyróżnikiem stała się wielokulturowość, i była miastem wielokulturowym aż do zakończenia II wojny światowej. W wyniku etnicznej segregacji duża część ludności niemieckiej i żydowskiej opuściła miasto. Swoją pamięć o Łodzi pielęgnowała w nowych warunkach społeczno-politycznych, poza Polską, często w rozproszeniu, w niewielkich skupiskach często skoncentrowanych wokół tzw. ziomkostw. Artykuł opisuje, w jaki sposób różne grupy narodowościowe (Polacy, Niemcy, Żydzi) pamiętały o wielokulturowym mieście po 1945 r., opierając się głównie na wspomnieniach i artykułach prasowych. Autorka zwraca również uwagę na fakt, że wszystkie te grupy funkcjonowały w odmiennej rzeczywistości społeczno-politycznej, która determinowała ich pamięć o wielokulturowym mieście.
KEBERADAAN PERUSAHAAN PERKERETAAPIAN NEDERLANDSCH-INDISCHE SPOORWEG MAATSCHAPPIJ DI SEMARANG TAHUN 1863-1873
Authors: Ningtyas Endah Mustika 
Published: February 2024

This study examines the Nederlandsch-Indische Spoorweg Maatschappij (NISM) Company in 1863-1873 which was founded in Semarang. Transportation in the Dutch East Indies before 1863, especially the Semarang Residency area, still used simple transportation to deliver goods and people. The main issues studied in this article are the development of the NISM Company from its construction to the completion of the railway line, and the impact of the railway operation on the government and society. The transportation company first used an engine-powered train by making the Semarang Residency the starting point for the railway line as well as the main office of the NISM Company. The research method used as a form of historical study is the historical method. The results of the study explained that the establishment of the NISM Company in the Residency of Semarang was due to the need for a mode of transportation to transport Cultivation products from the interior to the port.
Keywords: Semarang Residency; NISM Company; rail transportation
A host-microbial metabolite interaction gut-on-a-chip model of the adult human intestine demonstrates beneficial effects upon inulin treatment of gut microbiome
Authors: Donkers Joanne M. , Wiese Maria , van den Broek Tim J. , Wierenga Esmée , Agamennone Valeria , Schuren Frank , van de Steeg Evita 
Published: February 2024

Background: The gut and its microbiome have a major impact on many aspects of health and are therefore also an attractive target for drug- or food-based therapies. Here, we report on the added value of combining a microbiome screening model, the i-screen, with fresh intestinal tissue explants in a microfluidic gut-on-a-chip model, the Intestinal Explant Barrier Chip (IEBC).
Methods: Adult human gut microbiome (fecal pool of 6 healthy donors) was cultured anaerobically in the i-screen platform for 24 h, without and with exposure to 4 mg/mL inulin. The i-screen cell-free culture supernatant was subsequently applied to the luminal side of adult human colon tissue explants (n = 3 donors), fixed in the IEBC, for 24 h and effects were evaluated.
Results: The supplementation of the media with inulin promoted the growth of Anaerostipes , Bifidobacterium , Blautia , and Collinsella in the in vitro i-screen, and triggered an elevated production of butyrate by the microbiota. Human colon tissue exposed to inulin-treated i-screen cell-free culture supernatant or control i-screen cell-free culture supernatant with added short-chain fatty acids (SCFAs) showed improved tissue barrier integrity measured by a 28.2%-34.2% reduction in FITC-dextran 4000 (FD4) leakage and 1.3 times lower transport of antipyrine. Furthermore, the release of pro-inflammatory cytokines IL-1β, IL-6, IL-8, and TNF-α was reduced under these circumstances. Gene expression profiles confirmed these findings, but showed more profound effects for inulin-treated supernatant compared to SCFA-supplemented supernatant.
Conclusion: The combination of i-screen and IEBC facilitates the study of complex intestinal processes such as host-microbial metabolite interaction and gut health.
Primary Care Physician Preferences Regarding Communication from Orthopaedic Surgeons
Authors: Chiodo Christopher P. , Striano Brendan M. , Parker Emily , Smith Jeremy T. , Bluman Eric M. , Martin Elizabeth A. , Greco Julia M. , Healey Michael J. 
Published: February 2024

Background:
Musculoskeletal consultations constitute a growing portion of primary care physician (PCP) referrals. Optimizing communication between PCPs and orthopaedists can potentially reduce time spent in the electronic medical record (EMR) as well as physician burnout. Little is known about the preferences of PCPs regarding communication from orthopaedic surgeons. Hence, the present study investigated, across a large health network, the preferences of PCPs regarding communication from orthopaedists.

Methods:
A total of 175 PCPs across 15 practices within our health network were surveyed. These providers universally utilized Epic as their EMR platform. Five-point, labeled Likert scales were utilized to assess the PCP-perceived importance of communication from orthopaedists in specific clinical scenarios. PCPs were further asked to report their preferred method of communication in each scenario and their overall interest in communication from orthopaedists. Logistic regression analyses were performed to determine whether any PCP characteristics were associated with the preferred method of communication and the overall PCP interest in communication from orthopaedists.

Results:
A total of 107 PCPs (61.1%) responded to the survey. PCPs most commonly rated communication from orthopaedists as highly important in the scenario of an orthopaedist needing information from the PCP. In this scenario, PCPs preferred to receive an Epic Staff Message. Scenarios involving a recommendation for surgery, hospitalization, or a major clinical change were also rated as highly important. In these scenarios, an Epic CC’d Chart rather than a Staff Message was preferred. Increased after-hours EMR use was associated with diminished odds of having a high interest in communication from orthopaedists (odds ratio, 0.65; 95% confidence interval, 0.48 to 0.88; p = 0.005). Ninety-three PCPs (86.9%) reported spending 1 to 1.5 hours or more per day in Epic after normal clinical hours, and 27 (25.2%) spent >3 hours per day. Forty-six PCPs (43.0%) reported experiencing ≥1 symptom of burnout.

Conclusions:
There were distinct preferences among PCPs regarding clinical communication from orthopaedic surgeons. There was also evidence of substantial burnout and after-hours work effort by PCPs. These results may help to optimize communication between PCPs and orthopaedists while reducing the amount of time that PCPs spend in the EMR.
Natural History of Quantitative Fatty Infiltration and 3D Muscle Volume After Nonoperative Treatment of Symptomatic Rotator Cuff Tears
Authors: Hochreiter Bettina , Germann Christoph , Feuerriegel Georg C. , Sutter Reto , Selman Farah , Gressl Maximilian , Ek Eugene T. , Wieser Karl 
Published: February 2024

Background:
The severity of fatty infiltration (FI) predicts the treatment outcome of rotator cuff tears. The purpose of this investigation was to quantitatively analyze supraspinatus (SSP) muscle FI and volume at the initial presentation and after a 3-month minimum of conservative management. We hypothesized that progression of FI could be predicted with initial tear size, FI, and muscle volume.

Methods:
Seventy-nine shoulders with rotator cuff tears were prospectively enrolled, and 2 magnetic resonance imaging (MRI) scans with 6-point Dixon sequences were acquired. The fat fraction within the SSP muscle was measured on 3 sagittal slices, and the arithmetic mean was calculated (FISSP). Advanced FISSP was defined as ≥8%, pathological FISSP was defined as ≥13.5%, and relevant progression was defined as a ≥4.5% increase in FISSP. Furthermore, muscle volume, tear location, size, and Goutallier grade were evaluated.

Results:
Fifty-seven shoulders (72.2%) had normal FISSP, 13 (16.5%) had advanced FISSP, and 9 (11.4%) had pathological FISSP at the initial MRI scan. Eleven shoulders (13.9%) showed a ≥4.5% increase in FISSP at 19.5 ± 14.7 months, and 17 shoulders (21.5%) showed a ≥5-mm3 loss of volume at 17.8 ± 15.3 months. Five tears (7.1%) with initially normal or advanced FISSP turned pathological. These tears, compared with tears that were not pathological, had significantly higher initial mediolateral tear size (24.8 compared with 14.3 mm; p = 0.05), less volume (23.5 compared with 34.2 mm3; p = 0.024), more FISSP (9.6% compared with 5.6%; p = 0.026), and increased progression of FISSP (8.6% compared with 0.5%; p < 0.001). An initial mediolateral tear size of ≥20 mm yielded a relevant FISSP progression rate of 81.8% (odds ratio [OR], 19.0; p < 0.001). Progression rates of 72.7% were found for both initial FISSP of ≥9.9% (OR, 17.5; p < 0.001) and an initial anteroposterior tear size of ≥17 mm (OR, 8.0; p = 0.003). Combining these parameters in a logistic regression analysis led to an area under the receiver operating characteristic curve (AUC) of 0.913. The correlation between FISSP progression and the time between MRI scans was weak positive (ρ = 0.31).

Conclusions:
Three risk factors for relevant FI progression, quantifiable on the initial MRI, were identified: ≥20-mm mediolateral tear size, ≥9.9% FISSP, and ≥17-mm anteroposterior tear size. These thresholds were associated with a higher risk of tear progression: 19 times higher for ≥20-mm mediolateral tear size, 17.5 times higher for ≥9.9% FISSP, and 8 times higher for ≥17-mm anteroposterior tear size. The presence of all 3 yielded a 91% chance of ≥4.5% progression of FISSP within a mean of 19.5 months.

Level of Evidence:
Diagnostic Level II. See Instructions for Authors for a complete description of levels of evidence.
Housing and Inequalities in US Life Expectancy, Child and Youth Mortality, and All-Cause and Cause-Specific Mortality, 1979-2020: Results from the National Longitudinal Mortality Study and the National Vital Statistics System
Authors: Singh Gopal K. , Lee Hyunjung , Kim Lyoung Hee 
Published: February 2024

Background:
Limited research exists on the association between housing, life expectancy, and mortality disparities in the United States (US). Using longitudinal individual-level and pooled county-level mortality data from 1979 to 2020, we examine disparities in life expectancy, child and youth mortality, and all-cause and cause-specific mortality in the US by several housing variables.

Methods:
Using the 1979-2011 National Longitudinal Mortality Study (N=1,313,627) and the 2011-2020 linked county-level National Mortality Database and American Community Survey, we analyzed disparities in life expectancy and all-cause and cause-specific disparities by housing tenure, household crowding, and housing stability. Multivariate Cox proportional hazards regression was used to analyze individual-level mortality differentials by housing tenure. Age-adjusted mortality rates and rate ratios were used to analyze area-level disparities in mortality by housing variables.

Results:
US homeowners had, on average, a 3.5-year longer life expectancy at birth than renters (74.22 vs. 70.76 years), with advantages in longevity associated with homeownership being greater for males than for females; for American Indians/Alaska Natives, non-Hispanic Whites, and non-Hispanic Blacks than for Asian/Pacific islanders and Hispanics; and for the US-born than for immigrants. Compared with renters, homeowners had 22% lower risks of all-cause mortality, 15% lower child mortality, 17% lower youth mortality, and significantly lower mortality from cardiovascular diseases, all cancers combined, stomach, liver, esophageal and cervical cancer, diabetes, influenza and pneumonia, COPD, cirrhosis, kidney disease, HIV/AIDS, infectious diseases, unintentional injuries, suicide, and homicide.

Conclusion and Global Health Implications:
Several aspects of housing are strongly associated with life expectancy, child and youth mortality, and all-cause and cause-specific mortality in the US. Policies that aim to provide well-designed, accessible, and affordable housing to residents of both developed and developing countries are important policy options for addressing one of the most fundamental determinants of health for disadvantaged individuals and communities and for reducing health inequities globally.
Optimizing the Value of a CO2 Water-Alternating-Gas Injection Project under Geological and Economic Uncertainties
Authors: Ogbeiwi Precious , Stephen Karl D. 
Published: February 2024

Summary
The numerical simulations required for the robust optimization (RO) of the alternating injection of water and CO2 in hydrocarbon reservoirs are computationally expensive due to engineering, geological, and economic uncertainties. Using approximation models of the desired objective function(s) can significantly decrease the cost associated with the optimization routines while providing an adequate sampling of the input variables or uncertainties. In this study, we optimized the value of a water-alternating-gas (WAG) injection project in a Niger-Delta oil reservoir by applying the Markowitz classical theory to a suitable approximation model of the objective function. Our RO methodology incorporated significant geological and economic uncertainties—such as uncertainties due to the upscaling of the coarse-scale reservoir model and those due to the lack of other relevant geological and economic data—to the optimization routine to create better operating strategies for the projects that are risk-quantified. To compute the objective function, a novel economic model for the CO2 sequestration processes in the Niger-Delta hydrocarbon basin was applied. The result obtained in the presented case showed that a net present value (NPV) of at least USD 65.98 million was derived from the project depending on the engineer’s or user’s confidence level. Overall, the applicability of proxy models to RO routines was demonstrated. As a result, investment decisions that accounted for uncertainties and any potential variation in the field’s operation and development were made.
Analysis of Labour Movement Based on Island Model
Authors: Qi Tiange , Gao Yuning 
Published: February 2024

Abstract

This paper describes and
derives a Lucas-Prescott style island model, to model the location
choices of the heterogeneous agents by utilising endogenous
technology growth, which in turn influences personal human capital
growth. It leads to the U-shape curve of the inequality of wage
income with the technology of these islands but not in terms of
total income. In the extended two-goods model, the magnitude of the
implications is lessened by the impact the price of non-tradable
goods has as an automatic stabiliser. We found that skilled labours
with less endowed wealth tend to live in large cities for its high
salary. On the other hand, those less-skilled labours but with more
endowed wealth tend to live in cities with better environment,
which drives up the price level of non-tradable goods in these
cities. This explains the population concentration in the super
cities and the high housing price-wage ratio in some beautiful
cities.
Evaluation of different transport media for survival of H5N1 highly pathogenic avian influenza virus.
Authors: Dixit Baleshwari , Murugkar Harshad , Nagarajan Shanmugasundaram , Dixit Manu , Shrivastav Arpita , Kumar Anjay , Jha Amit K. , Mishra Anjani K. , Singh R V , Kumar Manoj 
Published: February 2024

Abstract
In the case of the H5N1 avian influenza outbreak, specific detection is critical for the timely implementation of control and preventive measures to limit the spread of the disease. Sample collection, storage, and transportation are critical for the accurate detection of the virus as its isolation and identification can only be done in a designated laboratory. In this study, we have compared 5 transport media out of which three are laboratory-based media named Phosphate-buffered Saline (PBS), 50% Glycerol + PBS, and Normal Saline (NS) and two are commercially available media including Viral Transport Medium (VTM), Charcoal based Viral Transport Medium (CVTM) to assess their effect on the survivability of virus in fecal swabs kept under field simulation conditions. Swabs from fecal samples spiked with known 50% embryo infectious dose (EID50) H5N1 virus were collected in each of these transport media, sealed, and stored with ice packs in thermocol boxes similar to the field samples that are being sent to the laboratory. Detection of the virus was done by isolation and reverse transcription-PCR. The results of our study suggested that the most effective transport media for H5N1 avian influenza virus was NS, PBS, and CVTM as the virus could be isolated for up to six days in comparison to VTM and PBS + 50% Glycerol.
USP20 mediates bladder cancer progression via altering the activity of Hippo-YAP axis through directly stabilizing YAP1 protein
Authors: Chen Wensun , Wu Siqi , Chen Yifan , Li Weijian , Liang Yingchun , Dai Xiyu , Chen Xi nan , Chen Yiling , Chen Tian , Liu Shenghua , Yang Chen , Jiang Hao wen 
Published: February 2024

Abstract

Yes-associated protein 1 (YAP1) mediated hippo pathway has attracted several research importance in various types of malignancies. The hampered Hippo-YAP1 axis in bladder cancer (BC) was identified as a major driver of BC progression and oncogenesis. The activity of Hippo pathway is controlled via regulation of phosphorylation cascade of MST1/2-LATS1/2-YAP1, while other modification as ubiquitination of hippo pathway protein also mediated the activity of Hippo pathway through the co-regulation of E3 ligases and deubiquitinases. In this study, we identified USP20 as a Hippo/YAP1 pathway activity related deubiquitinase through combined analysis of siRNA screening and deubiquitinase over-expression. Further analysis identified that USP20 directed regulated the YAP1 expression and target gene of YAP1, connective tissue growth factor (CTGF) as well as cysteine-rich angiogenic inducer 61 (CYR61). Tissue microarray assay confirmed that USP20 was elevated in tumor tissue and correlated with YAP1 expression. Mechanism study identified that USP20 directly interacted with YAP1 protein and promoted the stability of YAP1 protein through hampering the K48-linked poly-ubiquitination. Our findings in this study revealed that USP20 as a novel deubiquitinase in regulating the Hippo-YAP1 pathway in BC.