bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research-based Analytical Procedures to Evaluate Diabetic Biomarkers
and Related Parameters: In Vitro and In Vivo Methods
Authors: Rais Nadeem , Ved Akash , Ahmad Rizwan , Parveen Aashna 
Published: October 2023

Background:
The degenerative tendency of diabetes leads to micro- and macrovascular complications due to abnormal levels of biochemicals, particularly in patients with poor
diabetic control. Diabetes is supposed to be treated by reducing blood glucose levels, scavenging
free radicals, and maintaining other relevant parameters close to normal ranges. In preclinical
studies, numerous in vivo trials on animals as well as in vitro tests are used to assess the
antidiabetic and antioxidant effects of the test substances. Since a substance that performs poorly
in vitro won't perform better in vivo, the outcomes of in vitro studies can be utilized as a direct
indicator of in vivo activities.

Objective:
The objective of the present study is to provide research scholars with a
comprehensive overview of laboratory methods and procedures for a few selected diabetic
biomarkers and related parameters.

Method:
The search was conducted on scientific database portals such as ScienceDirect,
PubMed, Google Scholar, BASE, DOAJ, etc.

Conclusion:
The development of new biomarkers is greatly facilitated by modern technology
such as cell culture research, lipidomics study, microRNA biomarkers, machine learning
techniques, and improved electron microscopies. These biomarkers do, however, have some
usage restrictions. There is a critical need to find more accurate and sensitive biomarkers. With a
few modifications, these biomarkers can be used with or even replace conventional markers of
diabetes.
A Review on Diabetic Retinopathy
Authors: Kour Vijender , Swain Jayshree , Singh Jaspreet , Singh Hershdeep , Kour Harvinder 
Published: October 2023

Abstract:
Diabetic retinopathy is a well-recognised microvascular complication of diabetes and
is among the leading cause of blindness all over the world. Over the last decade, there have been
advances in the diagnosis of diabetic retinopathy and diabetic macular edema. At the same time,
newer therapies for the management of diabetic retinopathy have evolved. As a result of these
advances, a decline in severe vision loss due to diabetes has been witnessed in some developing
countries. However, there is a steady increase in the number of people affected with diabetes,
and is expected to rise further in the coming years. Therefore, it is prudent to identify diabetic
retinopathy, and timely intervention is needed to decrease the burden of severe vision loss. An
effort has been made to review all the existing knowledge regarding diabetic retinopathy in this
article and summarize the present treatment options for diabetic retinopathy.
Hybrid CNN-LSTM for Predicting Diabetes: A Review
Authors: Soltanizadeh Soroush , Naghibi Seyedeh Somayeh 
Published: October 2023

Background:
Diabetes is a common and deadly chronic disease caused by high
blood glucose levels that can cause heart problems, neurological damage, and other illnesses.
Through the early detection of diabetes, patients can live healthier lives. Many machine learning and deep learning techniques have been applied for noninvasive diabetes prediction. The
results of some studies have shown that the CNN-LSTM method, a combination of CNN and
LSTM, has good performance for predicting diabetes compared to other deep learning methods.

Method:
This paper reviews CNN-LSTM-based studies for diabetes prediction. In the CNNLSTM model, the CNN includes convolution and max pooling layers and is applied for feature
extraction. The output of the max-pooling layer was fed into the LSTM layer for classification.

Discussion:
The CNN-LSTM model performed well in extracting hidden features and correlations between physiological variables. Thus, it can be used to predict diabetes. The CNNLSTM model, like other deep neural network architectures, faces challenges such as training on
large datasets and biological factors. Using large datasets can further improve the accuracy of
detection.

Conclusion:
The CNN-LSTM model is a promising method for diabetes prediction, and compared with other deep-learning models, it is a reliable method.
A Review on Nano/Microfluidic Devices for Cell Isolation Techniques:
Recent Progress and Advances
Authors: Garshasbi Hamid Reza , Naghib Seyed Morteza 
Published: October 2023

Abstract:
Micro/nanofluidic devices and systems have gained increasing interest in healthcare
applications over the last few decades because of their low cost and ease of customization, with
only a small volume of sample fluid required. Many biological queries are now being addressed
using various types of single-molecule research. With this rapid rise, the disadvantages of these
methods are also becoming obvious. Micro/nanofluidics-based biochemical analysis outperforms traditional approaches in terms of sample volume, turnaround time, ease of operation, and
processing efficiency. A complex and multifunctional micro/nanofluidic platform may be used
for single-cell manipulation, treatment, detection, and sequencing. We present an overview of
the current advances in micro/nanofluidic technology for single-cell research, focusing on cell
capture, treatment, and biochemical analyses. The promise of single-cell analysis using micro/nanofluidics is also highlighted.
A Review on Comparison of Allopathic Medicines to other Drug Therapies in the Management of Asthma
Authors: Garg Ruchika , Piplani Mona , Upadhayay Ashutosh , Singh Yogendra , Bhateja Pankaj 
Published: October 2023

Abstract:Asthma, is a chronic disease of the airways and is characterized by exacerbations of bronchospasm and noticeable airway inflammation. Current asthma therapy has emerged from naturally occurring compounds through rational pharmaceutical advancements, and it is very beneficial. In this review, we have discussed the different drug therapies i.e., Ayurvedic, Homeopathic, Unani, and Allopathic affecting asthma treatment. Allopathic medicines are used as a controller medication for regular maintenance of asthma i.e., long-acting β-agonists, inhaled corticosteroids, anti-leukotriene medicines, and novel biologic agents. Pharmacological research is more important in generating effective, long-lasting, and safe asthma treatments, but it has been difficult to produce new classes of anti-asthmatic therapies. A combination inhaler that contains a long-acting β2-agonist and a corticosteroid is currently the "gold standard" for treating asthma. Allopathic treatments for asthma have been proven effective in reducing the probability of asthma attacks and for improving symptoms along with lung functions as compared to other therapies. The level of asthma management and the possible risk of future worsening are used to determine the treatment's strategies. This review article describes the comparison of allopathic therapy of asthma with homeopathy, ayurvedic and Unani system and gives justification supported by a number of case studies for being allopathic, a better therapy when compared with others.
Insights on the Correlation between Mitochondrial Dysfunction and the
Progression of Parkinson's Disease
Authors: Chauhan Prashant , Pandey Pratibha , Khan Fahad , Maqsood Ramish 
Published: October 2023

Abstract:
The aetiology of a progressive neuronal Parkinson's disease has been discussed in
several studies. However, due to the multiple risk factors involved in its development, such as
environmental toxicity, parental inheritance, misfolding of protein, ageing, generation of reactive
oxygen species, degradation of dopaminergic neurons, formation of neurotoxins, mitochondria
dysfunction, and genetic mutations, its mechanism of involvement is still discernible.
Therefore, this study aimed to review the processes or systems that are crucially implicated in
the conversion of MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) into its lethal form,
which directly blockades the performance of mitochondria, leading to the formation of oxidative
stress in the dopaminergic neurons of substantia nigra pars compacta (SNpc) and resulting in the
progression of an incurable Parkinson’s disease. This review also comprises an overview of the
mutated genes that are frequently associated with mitochondrial dysfunction and the progression
of Parkinson’s disease. Altogether, this review would help future researchers to develop an efficient
therapeutic approach for the management of Parkinson's disease via identifying potent
prognostic and diagnostic biomarkers.
Woodfordia fruticosa (L. Kurz): An Evidence-based Study of Its
Phytochemical and Pharmacological Activity
Authors: Singh Kuldeep , Gupta Jeetendra Kumar , Pathak Devender , Kumar Shivendra , Srivastava Ateet , Mishra Avinash Kumar , Patel Aman , Prajapati Harshit 
Published: October 2023

Abstract:
Woodfordia fruticosa (L.) Kurz, a member of the 'Lythraceae' family, has been used
in traditional medicine to cure common diseases since ancient times. It is traditionally used to
treat a variety of maladies such as the common cold, toothache, blood infection, leprosy, dysentery, wounds, rheumatic pain, fever, urinary issues, inflammation, antifertility, and menstrual
problems. The huge potential and impacts of this plant have been thoroughly confirmed in in
vitro and in vivo studies. The most current research on the plant Woodfordia fruticosa is critical
for identifying the bioactive components responsible for its medicinal efficacy. Phytochemical
studies reveal the existence of several chemicals extracted from various components of the plant,
including glycosides, terpenes, flavonoids, tannins, sterols, phenolics, and essential oils. According to pharmacological studies, the plant has many medicinal properties, such as hypoglycemic,
antioxidant, analgesic, hepatoprotective, antibacterial, gastric protective, and wound healing.
Most of the pharmacological effects of raw extracts of this plant have been described. Only a
few researchers have reported the activity of chemicals isolated from this plant. Therefore, this
research will help to discover the many different medicinal properties of the plant as well as its
pharmacological effects on various diseases and will show that further research is needed to explore its practical applications.
Decrypting the Pathological Pathways in IgA Nephropathy
Authors: Jash Rajiv , Maparu Kousik , Seksaria Sanket , Das Saptarshi 
Published: October 2023

Abstract:
IgAN is the most common form of glomerulonephritis affecting 2000000 people annually.
The disease ultimately progresses to chronic renal failure and ESRD. In this article, we
focused on a comprehensive understanding of the pathogenesis of the disease and thus identifying
different target proteins that could be essential in therapeutic approaches in the management
of the disease. Aberrantly glycosylated IgA1 produced by the suppression of the enzyme β-1, 3
galactosyltransferase ultimately triggered the formation of IgG autoantibodies which form complexes
with Gd-IgA1. The complex gets circulated through the blood vessels through monocytes
and ultimately gets deposited in the glomerular mesangial cells via CD71 receptors present locally.
This complex triggers the inflammatory pathways activating the alternate complement
system, various types of T Cells, toll-like receptors, cytokines, and chemokines ultimately recruiting
the phagocytic cells to eliminate the Gd-IgA complex. The inflammatory proteins cause
severe mesangial and podocyte damage in the kidney which ultimately initiates the repair process
following chronic inflammation by an important protein named TGFβ1. TGF β1 is an important
protein produced during chronic inflammation mediating the repair process via various
downstream transduction proteins and ultimately producing fibrotic proteins which help in the
repair process but permanently damage the glomerular cells.
Analisis Register Bahasa Pengrajin Batu-Bata di Desa Kampung Selamat, Kecamatan Rao Selatan, Kabupaten Pasaman Timur, Sumatera Barat (Kajian Sosiolinguistik)
Authors: Mulyadi Rahman , Kusmana Ade , Izar Julisah 
Published: October 2023

Penelitian ini bertujuan untuk mendiskripsikankan register bahasa Pengrajin Batu-bata di desa Kampung Selamat, Kecamatan Rao Selatan, Kabupaten Pasaman timur, Sumatera Barat. Register ini ditelaah dari aspek bentuk dan fungsinya yang tampak dalam ujaran para pengrajin batu-bata. Metode analisis data yang digunakan pada analisis data ini adalah metode deskriptif kualitatif yaitu memaparkan secara rinci bentuk dan fungsi register yang ada dalam ujaran pengrajin batu-bata. Penghimpunan data dibuat dengan metode terencana yakni orang yang ingin diwawancara terlebih dahulu izin atau diberi tahu bahwa akan direkam dan diteliti agar orang yang ingin kita harapkan datanya dapat menyampaikan data sesuai fakta. Teknik Pengumpulan data dilakukan dengan teknik tidak terencana, teknik simak, sadap dan teknik lanjutan sedangkan teknik analisis datanya adalah analisis deskriptif dengan memakai model analisis interaktif Miles dan Huberman yang meliputi reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian ini menunjukkakn terdapat 32 register dari bentuk register casual dengan fungsi yaitu fungsi emotif dan konatif.
Ungkapan Pujian Bahasa Melayu Jambi di Masyarakat Melayu Kota Jambi
Authors: Ramadhea Lerisa , Kusmana Ade , Izar Julisah 
Published: October 2023

Penelitian ini bertujuan untuk mengklasifikasikan dan mendeskripsikan jenis-jenis ungkapan pujian dan responnya, sekaligus fungsi dari pujian. Penelitian ini merupakan penelitian deskriptif kualitatif. Data dalam penelitian ini adalah ungkapan pujian pujian dan responnya dalam bahasa melayu Jambi. Sumber data dalam penelitian ini adalah masyarakat melayu kota Jambi. Pengumpulan data dalam penelitian ini menggunakan teknik observasi dan dokumentasi. Hasil dari penelitian ini adalah jenis ungkapan pujian yang tergolong dalam Kemampuan (Ability) ditemukan ada sebanyak 18 ungkapan pujian dan respon pujian sebanyak 9 jenis, Kepemilikan (Possession) ditemukan ada sebanyak 19 ungkapan pujian dan respon pujian sebanyak 8 jenis, Penampilan Fisik (Physical Appearance) ditemukan ada sebanyak 20 ungkapan pujian dan respon pujian sebanyak 5 jenis, Kepribadian (Personality) ditemukan ada sebanyak 20 ungkapan pujian dan respon pujian sebanyak 5 jenis, dan Kualitas (Quality) ditemukan ada sebanyak 10 ungkapan pujian dan respon pujian sebanyak 6 jenis. Adapun fungsi dari memberikan pujian pada orang lain yakni untuk mengekspresikan rasa kagum maupun rasa takjub yang disampaikan secara tulus atas pencapaian orang lain, penghargaan orang lain, untuk menjaga agar komunikasi verbal antara penutur dan mitra tutur dapat berjalan harmonis, untuk mengekspresikan rasa cemburu ataupun rasa iri terhadap pencapaian seseorang, penampilan seseorang, dan terhadap barang yang miliki orang lain. Dari hasil penelitian disimpulkan bahwa ungkapan pujian masih sering digunakan oleh masyarakat melayu Jambi, dari kelima jenis pujian tersebut yang paling sering digunakan adalah jenis pujian Penampilan Fisik (Physical Appearance), hal ini menujukkan masyarakat melayu Jambi sering memperhatikan penampilan fisik satu sama lainnya
Variasi Leksikal Bahasa Melayu Jambi di Kecamatan Taman Rajo dan Kecamatan Sekernan Kabupaten Muaro Jambi
Authors: Imansari Tarah , Ernanda Ernanda , Afria Rengki 
Published: October 2023

Abstract
This study aims to describe the forms of lexical variations and proportions found in Jambi Malay in Taman Rajo District and Sekernan District, Muaro Jambi Regency. This type of research uses qualitative and quantitative with a descriptive approach. The data used are from isolect informants with 200 Swadesh vocabularies. Data collection techniques in this study used observation techniques, interview techniques, fishing techniques, note-taking techniques, and recording techniques. The results of data analysis found 55 lexical variations from 200 Swadesh vocabularies and a percentage of 27.5% with 55 lexical variations vocabularies. The percentage shows the linguistic status, namely the difference in speech.
Abstrak
Penelitian ini bertujuan untuk mendeskripsikan bentuk variasi leksikal dan persentase yang terdapat dalam bahasa Melayu Jambi di Kecamatan Taman Rajo dan Kecamatan Sekernan Kabupaten Muaro Jambi. Jenis penelitian ini menggunakan kualitatif dan kuantitatif dengan pendekatan deskriptif. Data yang digunakan berasal dari isolek informan dengan 200 kosakata Swadesh. Teknik pengumpulan data dalam penelitian ini menggunakan teknik observasi, teknik wawancara, teknik pancing, teknik catat, dan teknik rekam. Hasil analisis data ditemukan 55 kosakata variasi leksikal dari 200 kosakata Swadesh dan persentase 27,5 % dengan 55 kosakata variasi leksikal. Persentase menunjukkan status kebahasaan yaitu perbedaan wicara.
Makna Leksikal dan Makna Kultural pada Ornamen-Ornamen dan Peninggalan-Peninggalan Sejarah di Rumah Tuo Rantau Panjang:Kajian Etnolinguistik
Authors: Rizkia Intan , Ernanda Ernanda , Izar Julisah 
Published: October 2023

This study aims to determine the lexical and cultural meanings of ornaments and historical relics at the Rumah Tuo Rantau Panjang in Merangin Regency, Jambi Province. The research method is descriptive with a qualitative approach. The data in this study are in the form of terms on ornaments and historical relics at the Rumah Tuo Rantau Panjang, which were obtained from two informants. The techniques used in collecting data are observation, documentation, interviews, and recording. Then the data obtained will be analyzed using several data analysis techniques, namely transcription, data codification, data classification, data description, and finally drawing conclusions. The results of this study are the description and documentation of the lexical and cultural meanings of the ornaments and historical relics at Rumah Tuo Rantau Panjang
Abstrak
Penelitian ini bertujuan untuk mengetahui makna leksikal dan makna kultural pada ornamen-ornamen dan peninggalan-peninggalan sejarah di Rumah Tuo Rantau Panjang yang berada di Kabupaten Merangin, Provinsi Jambi. Metode penelitian bersifat deskriptif dengan pendekatan kualitatif. Data dalam penelitian ini yaitu berupa istilah kata pada ornamen dan peninggalan-peninggalan sejarah di Rumah Tuo Rantau Panjang, yang diperoleh dari dua informan. Adapun teknik yang digunakan dalam mengumpulkan data yaitu, observasi, dokumentasi, wawancara, dan rekam. Kemudian data yang diperoleh akan dianalisis menggunakan beberapa teknik analisis data yaitu, transkripsi, kodifikasi data, klasifikasi data, deskripsi data, dan terakhir menarik kesimpulan. Hasil penelitian ini yaitu deskripsi dan dokumentasi makna leksikal dan makna kultural pada ornamen-ornamen dan peninggalan-peninggalan sejarah di Rumah Tuo Rantau Panjang.
Analisa Mimetik dan Ekspresif pada Album Musik "Be Life Goes on" milik Bangtan Sonyeondan
Authors: Amukti Dyah Ayu Sekar , Sabarun Sabarun , Qamariah Zaitun 
Published: October 2023

This study aimed to find out the relation between mimetic and expressive analysis on “BE: LIFE GOES ON” by Bangtan Sonyeondan and the educational implication of these analyses on “BE: LIFE GOES ON” by Bangtan Sonyeondan. The researcher used qualitative research. The researcher used the mimetic and expressive approach in the study. The data collection method was library research in which researchers collected data sources from books, journals, and other supporting sources related to the topic of this research. Therefore, the data of this study appears in the form of words, phrases, and sentences contained in the song lyrics on the album BE: Life Goes on. The researcher found there were meaning and educational values in several poems included in the six songs that had been analyzed. These values are the educational character values promoted by the government to develop virtuous character in the students.
Abstrak
Penelitian ini bertujuan untuk mengetahui hubungan antara analisis ekspresif mimetik a nd pada "BE: LIFE GOES ON" oleh Bangtan Sonyeondan dan implikasi pendidikan dari analisis th ese pada "BE: LIFE GOES ON" oleh Bangtan Sonyeondan. Penelitimenggunakan penelitian kualitatif. Peneliti menggunakan pendekatan mimetik dan ekspresif dalam penelitian ini. Metode pengumpulan data adalah penelitian kepustakaan dimana peneliti mengumpulkan sumber data dari buku, jurnal, dan sumber pendukung lainnya yang berkaitan dengan topik penelitian ini. Oleh karena itu, data penelitian ini muncul dalam bentuk kata, frasa, dan kalimat yang terdapat dalam lirik lagu pada album BE: Life Goes on. Peneliti menemukan ada makna dan nilai-nilai pendidikan dalam beberapa puisi yang termasuk dalam enam lagu yang telah dianalisis. Nilai-nilai tersebut merupakan nilai-nilai karakter pendidikan yang diusung oleh pemerintah untuk menumbuhkan karakter berbudi luhur pada peserta didik.
Kredo Puisi dan Mitos, Sebuah Ideologi Sastra Lisan dalam Karya Sutardji Calzoum Bachri
Authors: Maghfiroh Ahyatun , Karim Maizar , Rahariyoso Dwi 
Published: October 2023

Abstract
This research aims to find out how the ideology of oral literature in the kredo puisi becomes a model for creating poetry which is mythicalized in Sutardji Calzoum Bachri's poetry. The method that will be used in this research is a qualitative research method. The research data is in the form of kredo puisi with the data source being the poetry anthology book O Amuk Kapak by Sutardji Calzoum Bachri. The data collection technique used is the documentation technique. The analysis technique used is narrative analysis technique. This research will describe kredo puisi in the Roland Barthes mythical marking system, the aesthetic genealogy of Sutardji's poetry, typography as a style of Sutardji's orality, and a comparison between mantra and Sutardji's mantra poetry. Sutardji's deviance in presenting myths in the creation of poetry through kredo puisi is based on three aspects, namely freeing words from being occupied by meaning, freeing words from being occupied by grammar, and returning words to mantras. These three aspects direct the ideological form of writing Sutardji's poetry to the ideological form of orality.

Abstrak
Penelitian ini bertujuan untuk mengetahui bagaimana ideologi sastra lisan dalam kredo puisi menjadi model penciptaan puisi yang dimitoskan dalam karya Sutardji Calzoum Bachri. Metode yang akan digunakan dalam penelitian ini, yaitu metode penelitian kualitatif. Data penelitian ini berupa kredo puisi dengan sumber data berupa buku antologi puisi O Amuk Kapak karya Sutardji Calzoum Bachri. Teknik pengumpulan data yang digunakan, yaitu teknik dokumentasi. Adapun teknik analisis yang digunakan, yaitu teknik analisis naratif. Penelitian ini akan menguraikan kredo puisi dalam sistem penandaan mitos Roland Barthes, genealogi estetika berpuisi Sutardji, tipografi sebagai corak kelisanan Sutardji, serta perbandingan antara mantra dengan puisi mantra Sutardji. Penyimpangan yang dilakukan Sutardji untuk menghadirkan mitos dalam penciptaan puisi melalui kredo puisi didasarkan pada tiga aspek, yaitu membebaskan kata dari jajahan makna, membebaskan kata dari jajahan gramatika, dan mengembalikan kata kepada mantra. Ketiga aspek tersebut yang mengarahkan bentuk ideologi menulis puisi Sutardji kepada bentuk ideologi oralitas (kelisanan)