bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global and regional quality of care index (QCI) by gender and age in oesophageal cancer: A systematic analysis of the Global Burden of Disease Study 1990–2019
Authors: Iezadi Shabnam , Ebrahimi Narges , Ghamari Seyyed-Hadi , Esfahani Zahra , Rezaei Negar , Ghasemi Erfan , Moghaddam Sahar Saeedi , Azadnajafabad Sina , Abdi Zhaleh , Varniab Zahra Shokri , Golestani Ali , Langroudi Ashkan Pourabhari , Dilmaghani-Marand Arezou , Farzi Yosef , Pourasghari Hamid 
Published: October 2023

BackgroundThe aim of this study was to examine the quality of care by age and gender in oesophageal cancer using Global Burden of Disease (GBD) database.MethodsPatients aged 20 and over with oesophageal cancer were included in this longitudinal study using GBD 1990–2019 data. We used the Socio-Demographic Index (SDI) to classify the regions. We used Principal Component Analysis (PCA) method to calculate the Quality of Care Index (QCI). The QCI was rescaled into a 0–100 single index, demonstrating that the higher the score, the better the QC.ResultsThe age-standardized QCI for oesophageal cancer dramatically increased from 23.5 in 1990 to 41.1 in 2019 for both sexes, globally. The high SDI regions showed higher QCI than the rest of the regions (45.1 in 1990 and 65.7 in 2019) whereas the low SDI regions had the lowest QCI, which showed a 4.5% decrease through the years (from 13.3 in 1990 to 12.7 in 2019). Globally, in 2019, the QCI showed the highest scores for patients aged 80–84, reported 48.2, and the lowest score for patients aged 25–29 reported 31.5, for both sexes. Globally, in 2019, age-standardized Gender Disparity Ratio (GDR) was 1.2, showing higher QCI in females than males.ConclusionThere were fundamental differences in the QCI both globally and regionally between different age groups as well as between males and females. To achieve the goal of providing high-quality services equally to people in need in all over the world, health systems need to invest in effective diagnostic services, treatments, facilities, and equipment and to plan for screening and surveillance of high-risk individuals.
Abraçando a criança abandonada no Atendimento Psicoterápico Online: sob a perspectiva da Análise Bioenergética / Embracing the abandoned child in Online Psychotherapeutic Care: from the perspective of Bioenergetic Analysis
Authors: Alcocer Solange Andrea Díaz 
Published: October 2023

Resumo: Sabe-se que os primeiros meses de vida do bebê são fundamentais para cimentar as bases dos relacionamentos saudáveis da criança. Disso vai depender o tipo de vínculo e a forma com que se lida ante as exigências do meio ambiente. Qualquer conflito que aconteça neste período inicial, dará origem a uma tendência oral. O presente trabalho é um estudo de caso que objetivou abraçar a criança abandonada de uma paciente com 28 anos de idade, através do atendimento psicoterápico on-line, ao longo de 5 meses. Os resultados refletem as possibilidades de atuação e intervenções psicoterápicas, a partir da promoção das necessidades básicas que lhe foram negadas, e os diversos recursos que a Análise Bioenergética proporciona para além do consultório presencial. Palavras-chave: caráter oral, criança abandonada, Análise Bioenergética, atendimento psicoterápico on-line. Abstract:It is known that the first few months of a baby's life are essential for laying the foundations for a child's healthy relationships. This will depend on the type of bond and the way in which the demands of the environment are dealt with. Any conflict that happens in this initial period will give rise to an oral tendency. The present work is a case study that aimed to hug the abandoned child of a 28-year-old patient, through online psychotherapeutic care, over 5 months. The results reflect the possibilities of psychotherapeutic action and interventions, based on the promotion of the basic needs that were denied, and the various resources that Bioenergetic Analysis provides in addition to the face-to-face consultation.Keywords: oral character, abandoned child, Bioenergetic Analysis, Online Psychotherapeutic care.
Optimizing Timing of Follow-Up Colonoscopy: A Pilot Cluster Randomized Trial of a Knowledge Translation Tool
Authors: Shaffer Seth R. , Lambert Pascal , Unruh Claire , Harland Elizabeth , Helewa Ramzi M. , Decker Kathleen , Singh Harminder 
Published: October 2023

BACKGROUND:
Endoscopists have low adherence to guideline-recommended colonoscopy surveillance intervals. We performed a cluster-randomized single-blind pilot trial in Winnipeg, Canada, to assess the effectiveness of a newly developed digital application tool that computes guideline-recommended follow-up intervals.

METHODS:
Participant endoscopists were randomized to either receive access to the digital application (intervention group) or not receive access (control group). Pathology reports and final recommendations for colonoscopies performed in the 1–4 months before randomization and 3–7 months postrandomization were extracted. Generalized estimating equation models were used to determine whether the access to the digital application predicted guideline congruence.

RESULTS:
We included 15 endoscopists in the intervention group and 14 in the control group (of 42 eligible endoscopists in the city), with 343 patients undergoing colonoscopy before randomization and 311 postrandomization. Endoscopists who received the application made guideline-congruent recommendations 67.6% of the time before randomization and 76.1% of the time after randomization. Endoscopists in the control group made guideline-congruent recommendations 72.4% and 72.9% of the time before and after randomization, respectively. Endoscopists in the intervention group trended to have an increase in guideline adherence comparing postintervention with preintervention (odds ratio [OR]: 1.50, 95% confidence interval [CI] 0.82–2.74). By contrast, the control group had no change in guideline adherence (OR: 1.07, 95% CI 0.50–2.29). Endoscopists in the intervention group with less than median guideline congruence prerandomization had a significant increase in guideline-congruent recommendations postrandomization.

DISCUSSION:
An application that provides colonoscopy surveillance intervals may help endoscopists with guideline congruence, especially those with a lower preintervention congruence with guideline recommendations (ClincialTrials.gov number, NCT04889352).
Transcutaneous Auricular Vagal Nerve Stimulation Is Effective for the Treatment of Functional Dyspepsia: A Multicenter, Randomized Controlled Study
Authors: Shi Xin , Zhao Lina , Luo Hui , Deng Hui , Wang Xiangping , Ren Gui , Zhang Linhui , Tao Qin , Liang Shuhui , Liu Na , Huang Xiaojun , Zhang Xiaoyin , Yang Xuejuan , Sun Jinbo , Qin Wei , Kang Xiaoyu , Han Ying , Pan Yanglin , Fan Daiming 
Published: October 2023

INTRODUCTION:Vagal nerve stimulation (VNS) can be used to modulate gastrointestinal motility, inflammation, and nociception. However, it remains unclear whether VNS is effective in adult patients with functional dyspepsia (FD). We investigated the effectiveness of transcutaneous auricular VNS (taVNS) in patients with FD.METHODS:Consecutive patients with FD meeting Rome IV criteria with modified FD Symptom Diary score ≥10 were enrolled. Patients were randomly allocated to 10-Hz taVNS (V10 group), 25-Hz taVNS (V25 group), or sham group, with 30 minutes of treatment twice a day for 4 weeks. The primary outcome was the response rate at week 4, defined as the proportion of patients whose modified FD Symptom Diary score was reduced ≥5 when compared with the baseline. Secondary outcomes included adequate relief rate and adverse events.RESULTS:A total of 300 patients were randomized to V10 (n = 101), V25 (n = 99), and sham groups (n = 100). After 4 weeks of treatment, V10 and V25 groups had a higher response rate (81.2% vs 75.9% vs 47%, bothP< 0.001) and adequate relief rate (85.1% vs 80.8% vs 67%, bothP< 0.05) compared with the sham group. There was no significant difference between V10 and V25 in response rate and adequate relief rate (bothP> 0.05). The efficacy of taVNS (both 10 and 25 Hz) lasted at week 8 and week 12 during follow-up period. Adverse events were all mild and comparable among the 3 groups (1%–3%).DISCUSSION:Our study firstly showed that 4-week taVNS (both 10 and 25 Hz) was effective and safe for the treatment of adult FD (clinicaltrials.gov number: NCT04668534).
Adalimumab vs Infliximab in Luminal Pediatric Crohn's Disease: Comparable Outcomes in a Prospective Multicenter Cohort Study
Authors: deBruyn Jennifer C. , Huynh Hien Q. , Griffiths Anne M. , Jacobson Kevan , Mack David , Deslandres Colette , El-Matary Wael , Otley Anthony R. , Church Peter C. , Lawrence Sally , Wine Eytan , Sherlock Mary , Critch Jeffrey , Benchimol Eric I. , Jantchou Prévost , Rashid Mohsin , Carroll Matthew W. , Bax Kevin , Ricciuto Amanda , Carman Nicholas , Walters Thomas D. ,   and the Canadian Children IBD Network
Published: October 2023

INTRODUCTION:
This study compared real-world effectiveness between adalimumab (ADA) and infliximab (IFX) in children with Crohn's disease (CD).

METHODS:
Children enrolled into the prospective Canadian Children Inflammatory Bowel Disease Network National Inception Cohort between 2014 and 2020 who commenced ADA or IFX as first antitumor necrosis factor (anti-TNF) agent for luminal CD were included. Multivariate logistic regression modeled the propensity of commencing ADA; propensity score matching was used to match IFX-treated children to ADA-treated children. The primary outcome at 1 year was steroid-free clinical remission (SFCR). Secondary outcomes at 1 year were (i) combined SFCR and C-reactive protein remission, (ii) treatment intensification, and (iii) anti-TNF durability. Odds ratios (ORs) and hazard ratio adjusted for concomitant immunomodulator use with 95% confidence interval (CI) are reported.

RESULTS:
In the propensity score-matched cohort of 147 ADA-treated and 147 IFX-treated children, 92 (63%) ADA-treated and 87 (59%) IFX-treated children achieved SFCR at 1 year (adjusted OR 1.4, 95% CI 0.9–2.4); 75 of 140 (54%) ADA-treated and 85 of 144 (59%) IFX-treated children achieved combined SFCR and C-reactive protein remission (adjusted OR 1.0, 95% CI 0.6–1.6). ADA-treated children less frequently underwent treatment intensification (21 [14%]) compared with IFX-treated children (69 [47%]) (P < 0.0001). Discontinuation of anti-TNF occurred in 18 (12%) ADA-treated and 15 (10%) IFX-treated children (adjusted hazard ratio 1.2, 95% CI 0.6–2.2).

DISCUSSION:
Children with CD achieved favorable outcomes at 1 year with either ADA or IFX as first anti-TNF agents. Those receiving IFX did not have significantly superior outcomes compared with clinically similar children receiving ADA.
Potensi Karbon Biru Pesisir Kalimantan Barat
Authors: Putri Ayunda Annisa , Akbar Aji Ali , Romiyanto Romiyanto , Jati Dian Rahayu , Saziati Ochih 
Published: October 2023

Potensi karbon biru (blue carbon) di pesisir Kalimantan Barat terdapat pada ekosistem mangrove, padang lamun, dan terumbu karang. Ketiga ekosistem ini tersebar di Kabupaten Sambas, Bengkayang, Mempawah, Kubu Raya, Ketapang dan Kota Singkawang. Penelitian ini bertujuan mengetahui luas dan keanekaragaman jenis ekosistem pesisir terkait dengan potensi karbon biru. Metode non-destruktif digunakan untuk mengkaji kemampuan ekosistem pesisir dalam menyerap karbon. Mangrove didominasi jenis didominasi oleh Rhizophora spp., Avicennia spp. Bruguiera spp., Sonneratia alba, Excoeacaria agallocha, dan Nypa fruticans. Padang lamun didominasi jenis Thalassia hemprichii dan Enhalus acoroides, sementara terumbu karang didominasi jenis Porites spp. dan Montipora spp. Estimasi serapan karbon terbesar berada di Kubu Raya sebesar 0,026 PgC (0,095 PgCO2e) dan yang terkecil berada di Kota Singkawang sebesar 0,000032 PgC (0,00012 PgCO2e). Penelitian ini mengungkap bahwa kemampuan serapan karbon berbanding lurus dengan luas ekosistem pesisir. Ekosistem mangrove merupakan ekosistem yang memiliki kemampuan dalam menyerap karbon, daripada ekosistem lamun dan terumbu karang. Upaya antropegenik memperparah degradasi ekosistem di pesisir Kalimantan Barat. The potency of blue carbon in the West Kalimantan is found in mangroves, seagrass beds, and coral reefs ecosystem. Sambas, Bengkayang, Mempawah, Kubu Raya, Ketapang, and Singkawang regencies coastal had a big potential blue carbon. This study aims to estimate the potential of blue carbon on coastal ecosystems diversity. This research was applying a non-destructive method to quantify the carbon sequestration of the ecosystems. Rhizophora spp., Avicennia spp, dominates mangrove, in Kalimantan Barat. Bruguiera spp., Sonneratia alba, Excoeacaria agallocha, dan Nypa fruticans, for mangroves, Thalassia hemprichii and Enhalus acoroides for seagrass and Porites spp. and Montipora spp, for coral reefs. The most extensive estimated carbon sequestration is in Kubu Raya regency with 0.026 PgC (0.095 PgCO2e), and the smallest one is in the Singkawang regency with 0.000032 PgC/ha (0.00012 PgCO2e/ha). Based on this research, it is observed that the ability of carbon sequestration is directly influenced by the coverage area of the coastal ecosystem, especially the mangrove forest which are dynamic due to anthropogenic activities.
Pandemic and Cultural Industries in a Regional Context
Authors: Bérubé Julie 
Published: October 2023

The COVID-19 pandemic has greatly shaken the cultural industries. Researchers report significant financial and job losses worldwide for these industries. Much of the research on the pandemic and the cultural industries has focused on large cities. The objective of this research is to understand the impact of the pandemic on regional cultural industries. We studied the Outaouais region in Canada by conducting focus groups and semi-structured interviews with artists and cultural workers. Our results report on the problems caused by the pandemic, the spin-offs it has generated, the initiatives that have emerged and the role of cultural organizations during the pandemic. This research contributes to the advancement of knowledge by describing the situation of cultural industries in a regional context during the pandemic. The results of this research encourage the maintenance of certain activities in virtual or hybrid mode, the development of grant programs to attract artists to the region, and the development of events or platforms to promote networking between artists andcultural organizations.
ErbB4 promotes M2 activation of macrophages in idiopathic pulmonary fibrosis
Authors: Jiang Yu , Shi Jialin , Zhou Junhao , He Chunxiao , Gu Ruinan 
Published: October 2023

Abstract
Idiopathic pulmonary fibrosis (IPF) is the most common and fatal diffuse fibrotic lung disease accompanied by macrophage M2 activation. ErbB4 is involved in and affects the process of inflammation. In this study, we determined that the mRNA level and protein expression of ErbB4 and M2 cytokine members were increased in the serum of IPF patients. In mouse alveolar macrophage MH-S cells, after knocking down ErbB4 by siRNA, the mRNA level and protein expression of M2 activator induced by interleukin (IL)-4 were decreased compared with the control group. Activating by ErbB4 agonist neuromodulatory protein (NRG)-1, IL-4-induced M2 program was promoted. Mechanistically, treated with NRG-1 in MH-S cells, the phosphorylation level of Akt did not change, while the phosphorylation level of ERK increased. Using SCH772984 to inhibit ERK pathway, the increasing IL-4-induced M2 activation by NRG-1 was inhibited, and the high level of M2 activator protein expression and mRNA expression was restored. Collectively, our data support that ErbB4 and M2 programs are implicated in IPF, and ErbB4 participates in the regulation of M2 activation induced by IL-4 through the ERK pathway.
Establishment of reference intervals for free light chains and immunoglobulins in Saudi population
Authors: Borai Anwar , Ichihara Kiyoshi , Tamimi Waleed , Masaud Abdulaziz , Sobki Samia 
Published: October 2023

Abstract

Objectives
Testing of serum-free light chains kappa (κ) and lambda (λ), along with ratio (FLCR) is essential for the diagnosis and management of monoclonal gammopathies. Accurate clinical diagnosis depends upon appropriate local population reference intervals (RIs). This study examined the Saudi population for serum-free light chains and other immunoglobulins to establish RIs and to explore variations in the test results by using the International Federation for Clinical Chemistry and Laboratory Medicine’s global protocol for harmonized implementation of RI study.

Methods
A total of 180 healthy Saudi adults were recruited. All serum samples were assayed using the Freelite reagents from the Binding Site. The variation in reference values attributable to sex, age, BMI, and region was calculated by ANOVA as a standard deviation ratio (SDR). The RIs for the FLCR were derived by the parametric method and validated by using samples from patients with hypo- and hypergammaglobulinemia.

Results
The new RIs for free κ and FLCR were shifted to a higher side from the manufacturer-adapted RIs. Based on the SDR cutoff value (>0.4), between-sex partition RIs were not required for all analytes except IgM. Validation using patients with hypo- or hypergammaglobulinemia and without multiple myeloma, was all within the new RI. BMI, smoking, and exercise were not relevant sources of variation for any analyte.

Conclusions
Locally derived RIs for free light chains and immunoglobulins analytes specific for Saudis were established after careful consideration of various factors. These RIs were more reliable than those provided as guidance by the manufacturer, or from other countries, for appropriate classification and prediction of disease progression for Saudi patients.
On the Iwasawa invariants of BDP Selmer groups and BDPp-adicL-functions
Authors: Lei Antonio , Müller Katharina , Xia Jiacheng 
Published: October 2023

AbstractLetpbe an odd prime. Letf1{f_{1}}andf2{f_{2}}be weight 2 cuspidal Hecke eigenforms with isomorphic residual Galois representations atp. Greenberg–Vatsal and Emerton–Pollack–Weston showed that ifpis a good ordinary prime for the two forms, the Iwasawa invariants of theirp-primary Selmer groups andp-adicL-functions over the cyclotomicℤp{\mathbb{Z}_{p}}-extension ofℚ{\mathbb{Q}}are closely related. The goal of this article is to generalize these results to the anticyclotomic setting. More precisely, letKbe an imaginary quadratic field wherepsplits. Suppose that the generalized Heegner hypothesis holds with respect to both(f1,K){(f_{1},K)}and(f2,K){(f_{2},K)}. We study relations between the Iwasawa invariants of the BDP Selmer groups and the BDPp-adicL-functions off1{f_{1}}andf2{f_{2}}.
Double lacunary statistical convergence of Δ-measurable functions on product time scales
Authors: Dutta Hemen , Bhattarai Pallav 
Published: October 2023

Abstract
We first present a notion of a double lacunary sequence on product time scales. Using this notion, we define the notions of the double lacunary statistical convergence and double lacunary strongly p-Cesàro summability of 2-multiple functions on product time scales and we study some fundamental properties of both notions. We also present a theorem that connects the above-mentioned two concepts. Furthermore, we define a refinement of a double lacunary sequence on product time scales and provide some fundamental properties as well as inclusion theorems for a refined and a non-refined double lacunary sequence on product time scales.
The commuting conjugacy class graphs of finite groups with a given property
Authors: Rezaei Mehdi , Foruzanfar Zeinab 
Published: October 2023

Abstract
Let G be a finite non-abelian group. The commuting conjugacy class graph

Γ
⁢

(
G
)

{\Gamma(G)}

is defined as a graph whose vertices are non-central conjugacy classes of G and two distinct vertices X and Y in

Γ
⁢

(
G
)

{\Gamma(G)}

are connected by an edge if there exist elements

x
∈
X

{x\in X}

and

y
∈
Y

{y\in Y}

such that

x
⁢
y

=

y
⁢
x

{xy=yx}

. In this paper, the structure of the commuting conjugacy class graph of group G with the property that

G

Z
⁢

(
G
)

{\frac{G}{Z(G)}}

is isomorphic to a Frobenius group of order pq or

p
2

⁢
q

{p^{2}q}

, is determined.
New analytical technique to solve fractional-order Sharma–Tasso–Olver differential equation using Caputo and Atangana–Baleanu derivative operators
Authors: Chauhan Jignesh P. , Khirsariya Sagar R. , Hathiwala Gautam S. , Biswas Hathiwala Minakshi 
Published: October 2023

Abstract
The present work introduces a novel approach, the Adomian Decomposition Formable Transform Method (ADFTM), and its application to solve the fractional order Sharma-Tasso-Olver problem. The method’s distinctive outcomes are highlighted through a comparative analysis with established non-local Caputo fractional derivatives and the non-singular Atangana–Baleanu (ABC) fractional derivatives. To provide a comprehensive understanding, the proposed ADFTM’s approximate solution is compared with the homotopy perturbation method (HPM) and residual power series method (RPSM). Further, numerical and graphical results demonstrate the reliability and accuracy of the ADFTM approach. The novel outcomes presented in this work emphasize its capability to address complex engineering problems effectively. By demonstrating its efficacy in solving the fractional order problems, the new ADFTM proves to be a valuable tool in solving scientific problems.
On theX-ray transform of planar symmetric tensors
Authors: Omogbhe David , Sadiq Kamran 
Published: October 2023

AbstractIn this article we characterize the range of the attenuated and non-attenuatedX-ray transform of compactly supported symmetric tensor fields in the Euclidean plane. The characterization is in terms of a Hilbert-transform associated withA-analytic maps in the sense of Bukhgeim.
Mitochondrial DNA and karyotype data reveal new records of Alouatta sara Elliot, 1910 (Atelidae, Alouattinae) in the Western Amazon, Brazil
Authors: Povill Cintia , Ribeiro Maria Clara Santos , do Carmo Elaine Christina Oliveira , D’Andrea Paulo Sérgio , Bonvicino Cibele Rodrigues 
Published: October 2023

Abstract

Alouatta is composed of groups of species of which the Amazonian Alouatta seniculus group is part. The number of species in this group is not consensus, some authors considered as species some taxa previously considered as subspecies of A. seniculus: A. seniculus, Alouatta sara, Alouatta s. puruensis, Alouatta s. juara, and Alouatta arctoidea. In order to investigate the genetic diversity of Alouatta in the Purus River basin, we examined the karyotypes of individuals from this region and conducted analyses using Cytochrome b sequences, which yielded valuable information on species diversity and revealed the presence of A. sara in western Brazil, expanding its known distribution range.
Mean ergodic theorems for a sequence of nonexpansive mappings in complete CAT(0) spaces and its applications
Authors: Termkaew Sakan , Chaipunya Parin , Kohsaka Fumiaki 
Published: October 2023

Abstract
In this article, we prove ergodic convergence for a sequence of nonexpansive mappings in Hadamard (complete

CAT

(

0

)

{\rm{CAT}}\left(0)

) spaces. Our result extends the nonlinear ergodic theorem by Baillon for nonexpansive mappings from Hilbert spaces to Hadamard spaces. We further establish the standard nonlinear ergodic theorem and apply our results to the problem of finding a common fixed point of a countable family of nonexpansive mappings. Finally, we propose some applications of our results to solve convex optimization problems in Hadamard spaces.