bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meckel's diverticulum: analysis of 27 cases in an adult population
Authors: Hernández Juan David , Valencia Gustavo , Girón Felipe , García Sierra Andrés Mauricio , Núñez-Rocha Ricardo E. , Rodríguez Lina M. , Rey Chaves Carlos Eduardo , Londoño Eduardo Emilio , Nassar Ricardo 
Published: December 2023

BackgroundMeckel's diverticulum is a rare congenital pathology among newborns. Nevertheless, it is an uncommon abdominal pathology in the adult population. Therefore, we aim to provide a detailed account of our surgical approach in treating 27 cases of Meckel's diverticulum.MethodsThis study is a cross-sectional analysis that utilized a database with prospectively collected data from 2004 to 2022. All patients under the age of 18 were excluded from the population. We described the population’s demographic characteristics, symptoms, anatomopathological study, surgical technique, complications, morbidity, and mortality. A subgroup analysis was performed between the symptomatic and asymptomatic patients.ResultsA total of 27 patients who underwent surgical resection for a posteriorly diagnosed Meckel's diverticulum were included. The male population accounted for 81.4% (n = 22) of the sample size. The symptomatic group consisted of 18 male and four female patients. Abdominal pain was the predominant symptom in 85% of the patients. Out of the 22 symptomatic patients, only 9% had a positive perioperative diagnosis of Meckel's diverticulum. All 27 patients with diverticulum diagnosis received the resection through diverticulectomy (n = 6), small bowel resection with end-to-end anastomosis (n = 6), and small bowel resection with lateral to lateral anastomosis (n = 15). The mean distance between the diverticulum and the ileocecal valve was 63.4 cm. The symptomatic group had an average diverticulum length of 3.54 cm, with an average base width of 2.47 cm. In the other group, the values were 2.75 and 1.61 cm. The average length of hospital stay in the symptomatic group was 7.3 days.ConclusionsMeckel's diverticulum is a rare pathology in the adult population. Its presentation varies from asymptomatic to symptomatic patients, and surgery is the cornerstone treatment for this pathology.
Next Generation Therapeutic Strategy for Treatment and Prevention of Alzheimer’s Disease and Aging-Associated Cognitive Decline: Transient, Once-in-a-Lifetime-Only Depletion of Intraneuronal Aβ (iAβ) by Its Targeted Degradation via Augmentation of Intra-iAβ-Cleaving Activities of BACE1 and/or BACE2
Authors: Volloch Vladimir , Rits-Volloch Sophia 
Published: December 2023

Although the long-standing Amyloid Cascade Hypothesis (ACH) has been largely discredited, its main attribute, the centrality of amyloid-beta (Aβ) in Alzheimer’s disease (AD), remains the cornerstone of any potential interpretation of the disease: All known AD-causing mutations, without a single exception, affect, in one way or another, Aβ. The ACH2.0, a recently introduced theory of AD, preserves this attribute but otherwise differs fundamentally from the ACH. It posits that AD is a two-stage disorder where both stages are driven by intraneuronal (rather than extracellular) Aβ (iAβ) albeit of two distinctly different origins. The first asymptomatic stage is the decades-long accumulation of Aβ protein precursor (AβPP)-derived iAβ to the critical threshold. This triggers the activation of the self-sustaining AβPP-independent iAβ production pathway and the commencement of the second, symptomatic AD stage. Importantly, Aβ produced independently of AβPP is retained intraneuronally. It drives the AD pathology and perpetuates the operation of the pathway; continuous cycles of the iAβ-stimulated propagation of its own AβPP-independent production constitute an engine that drives AD, the AD Engine. It appears that the dynamics of AβPP-derived iAβ accumulation is the determining factor that either drives Aging-Associated Cognitive Decline (AACD) and triggers AD or confers the resistance to both. Within the ACH2.0 framework, the ACH-based drugs, designed to lower levels of extracellular Aβ, could be applicable in the prevention of AD and treatment of AACD because they reduce the rate of accumulation of AβPP-derived iAβ. The present study analyzes their utility and concludes that it is severely limited. Indeed, their short-term employment is ineffective, their long-term engagement is highly problematic, their implementation at the symptomatic stages of AD is futile, and their evaluation in conventional clinical trials for the prevention of AD is impractical at best, impossible at worst, and misleading in between. In contrast, the ACH2.0-guided Next Generation Therapeutic Strategy for the treatment and prevention of both AD and AACD, namely the depletion of iAβ via its transient, short-duration, targeted degradation by the novel ACH2.0-based drugs, has none of the shortcomings of the ACH-based drugs. It is potentially highly effective, easily evaluable in clinical trials, and opens up the possibility of once-in-a-lifetime-only therapeutic intervention for prevention and treatment of both conditions. It also identifies two plausible ACH2.0-based drugs: activators of physiologically occurring intra-iAβ-cleaving capabilities of BACE1 and/or BACE2.
THE EFFECTS OF SP6 AND LI4 ACUPRESSURE POINTS ON PAIN AND DURATION REDUCTION DURING THE FIRST STAGE OF LABOR: AN EVIDENCE-BASED CASE REPORT
Authors: Salsabila Farah , Hidayanti Desi 
Published: December 2023

Background: Painless delivery and effective labor pain management are among the strategies to encourage vaginal delivery and reduce the rate of cesarean section. Several non-pharmacological methods, such as acupressure, can be performed to reduce labor pain and shorten the duration of delivery.
Method: Advanced search for literatures in ProQuest, Willey, and Scopus was conducted in April, 2022.
Objectives: To observe the effect of acupressure on relieving pain and reducing time during the first stage of labor.
Result: There were three articles relevant with the eligibility criteria. Three studies of randomized controlled trials showed that acupressure on SP6 point could relieve pain and acupressure on LI4 point could reduce time during the first stage of labor. A systematic review and meta-analysis found that acupressure on SP6 and LI4 points could manage length and pain severity of labor.
Conclusion: Application of combining acupressure on SP6 and LI4 was found to have an effect on relieving labor pain and reducing labor time during the first stage
Orta Çağ'ın Kristolojik Sembollerinden Biri Olarak Unikorn
Authors: ÖNER Yasin 
Published: December 2023

Öz
Çalışmanın konusu Hıristiyan sanat ve düşünce tarihinde İsa Mesih için kullanılmış sembollerden biri olan unikorn adlı mitik varlıkla ilgili aktarılan bilgilerin değerlendirilmesidir. Bu anlamda İsa Mesih’in misyonu ve özellikleri bağlamında kullanılan ve Orta Çağ’dan başlamak üzere gerek İsa’nın Bakire Meryem’e müjdelenmesi gerekse çarmıhta insanlığın günahları adına kendini feda etmesini konu edinen sanat eserlerinde ön plana çıkan unikorn, alnının ortasında yer alan ve onu diğer hayvanlardan farklı kılan tek boynuzuyla bu üne kavuşmuştur. Ancak bahsi geçen tek boynuz sadece unikornla özdeşleştirilmemiş, ondan asırlar önce çeşitli kültürlerde de bu özelliğe sahip olan hayvanlardan bahsedilmiştir. Bu anlamda çalışmanın amacı Hindistan’dan Çin’e, İran’dan Yunan’a kadar, hatta günümüzde edindiği anlam da dahil olmak üzere farklı kültürlerde varlığı kabul edilen tek boynuzlu atlarla ilgili anlatıları ortaya koyarak unicornun Hıristiyanlıktaki karşılığını, yani İsa Mesih’in bir sembolü olarak kullanılmasıyla ilgili arka planı ortaya koymaktır. Bu amaca hizmet edecek şekilde öncelikle bu sembolün çeşitli kültürlerdeki özellikleri ile Hıristiyanlıktaki anlamları arasında karşılaştırma yöntemi kullanılarak benzerlikler ve farklılıklar ortaya konulmuştur. Ayrıca bu sembol özelinde Hıristiyan inanç ve öğretilerini merkeze alan metinler analiz edilerek konunun sınırları dahilinde deskriptif/tasvir edici yöntemle bilgiler elde edilmiştir. İnancın açığa çıkmasında farklı sembolik ögelerden faydalanan Hıristiyanlık, özellikle İsa Mesih’in yaşamına dair oldukça karmaşık olan hususları bu tür sembollerden faydalanarak açıklamaya ve buna benzer somut varlıklar üzerinden örneklendirme yoluyla insan zihnine kabul ettirmeye çalışmıştır. Avcıların yakalamaktan aciz kaldığı son derece hızlı ve güçlü bir hayvan olarak tasvir edilen unikornun, bir bakire tarafından kandırılması ve avcılar tarafından esaret altına alınması yönündeki hikâyeyi İsa Mesih’in tutkusu çerçevesinde yorumlayan Hıristiyan teologlar, Orta Çağ boyunca sanatın farklı varyasyonlarında bu hayvanın kristolojik bir sembol olarak anılmasına katkıda bulunmuşlardır. Böylece “gerçek mi, efsane mi?” tartışmalarına gerek kalmaksızın Mesih’in görsel bir sembolü haline gelen unikornun Hıristiyanlığı ilgilendiren boyutu, çağları aşacak düzeye ulaşmıştır.
Takva Ölçeği: Geçerlik Güvenirlik Çalışması
Authors: YİĞİT Yasin , ACAR Tuba 
Published: December 2023

Takva Ölçeği: Geçerlik Güvenirlik Çalışması
Taqwa Scale: Validity and Reliability Study

Yasin Yiğit
Doç. Dr. Iğdır Üniversitesi, İlahiyat Fakültesi, Din Eğitimi Anabilim Dalı
Assoc. Dr. Iğdır University Faculty of Theology, Department of Religious Education
Iğdır/Türkiye
yasnyigit@gmail.com
orcid.org/0000-0002-3254-5350

Tuba Acar
Yüksek Lisans Öğrencisi, Iğdır Üniversitesi, Lisansüstü Eğitim Enstitüsü, Felsefe ve Din Bilimleri Anabilim Dalı
Graduate Student, Iğdır University, Graduate School of Education, Department of Philosophy and Religious Studies
Iğdır/Türkiye
tubaacar1453@gmail.com
orcid.org/0000-0001-7490-9549

Öz
Takvanın İslam’da Allah’a karşı duyulan derin saygıdan ötürü onun rızasına uygun davranışlar gösterme hususunda hassas davranmak anlamında kullanıldığı ifade edilebilir. Kur’an-ı Kerim’de geçen ayetlerden anlaşılabileceği üzere takva sahibi olan Müslümanlar İslam dininin inanç, ibadet ve ahlak esaslarını kişilik haline getirmiş, haram olduğundan şüphe duyduğu davranışlardan bile kaçınmaya çalışan kişilerdir. İslam’ın yetiştirmek istediği insan modelinde takvalı olma özelliği öne çıkmaktadır. Bu nedenle İslam eğitiminin yapıldığı örgün ve yaygın öğretim kurumlarında takvalı bireylerin yetişmesinin önemli olduğu düşünülebilir. Günümüzde Türkiye şartlarında bilhassa imam hatip ortaokulları ve liselerinde, İlahiyat/İslâmî ilimler fakültelerinde ve Diyanet İşleri Başkanlığına bağlı yaygın din öğretimi kapsamında takva bir amaç olarak benimsenebilir. Takvanın amaç olarak benimsenmesi bilimsel çalışmalarda bu hedefe ne düzeyde ulaşıldığının araştırılmasını gerektirir. Bu çalışmada takva düzeyini ölçen geçerli ve güvenilir bir ölçme aracının geliştirilmesi amaçlanmıştır. Çalışma, keşfedici sıralı desene göre tasarlanmıştır. Araştırmanın çalışma grubu Atatürk Üniversitesi İlahiyat Fakültesi öğrencileridir. Çalışma sürecinde ilk olarak madde analizi yapmak amacı ile 81 kişiye ulaşılmıştır. Bunun akabinde açımlayıcı faktör analizi ve güvenilirlik analizi için 309, doğrulayıcı faktör analizi için 550 kişiye ulaşılmıştır. Daha sonra ölçek geliştirme aşamaları sistemli bir şekilde takip edilerek katılımcılardan elde edilen veriler SPSS 23 ve AMOS 23 istatistik paket programları aracılığıyla incelenmiştir. Bu süreçte yapılan açımlayıcı faktör analizi sonucunda toplam varyansın %48.198’ini açıklayan 14 madde ve 3 boyuttan oluşan bir yapı oluşmuş, doğrulayıcı faktör analizi bu yapıyı desteklemiştir. Modelin uyum indeksleri x2/sd=2.800, RMSEA=.057, RMR=.029, SRMR=.052, AGFI=.923, CFI=.904, TLI=.918, IFI=.904, NFI=.902, GFI=.946 şeklindedir. Ölçeğin Cronbach Alfa değeri .83’tür. Bu sonuçlara göre tüm parametreler istatistiksel olarak anlamlı bulunmuş, ölçeğin geçerli ve güvenilir olduğu anlaşılmıştır. Takva Ölçeği’nin birinci faktörünün ismi Günlük Yaşamda Takvalı Olma, ikinci faktörünün ismi İbadetlerde Takvalı Olma, üçüncü faktörünün ismi Takvayı Kişilik Haline getirmedir. Bu ölçekten meseleyle ilgili nicel araştırmalarda yararlanılabilir.
Anahtar Kelimeler: Din Eğitimi, İslam Öğretimi, Ölçek Geliştirme, Takva, Takva Ölçeği
Improvement of optic nerve head perfusion and reversible visual field defect following XEN Gel Stent implant
Authors: Birapadian Shiivaa Manjare , Tang Seng Fai , Lam Chenshen , Md Din Norshamsiah 
Published: December 2023

Background: Patients with juvenile onset ocular hypertension (OHT) have high intraocular pressure (IOP) and may develop early glaucomatous disc damage.
Case presentation: A 26-year-old woman with family history of glaucoma was diagnosed with OHT at age 18. Her vision was 6/6, with a bilateral cup-to-disc ratio of 0.5, normal visual field (VF), and IOP in the mid-teens on 2 topical antiglaucoma medications. The patient started having IOP spikes (20–48 mmHg) in her left eye despite maximum tolerable medical therapy, associated with intermittent headache and nasal step defect on VF test. XEN Gel Stent was implanted and IOP reduced to 10–14 mmHg without medical therapy. Optical coherence tomography angiography showed improvement in optic nerve head (ONH) perfusion density and flux, while the VF defect disappeared.
Conclusion: Improvement in ONH perfusion and reversibility of early glaucomatous VF defect is feasible with prompt XEN Gel Stent implant in juvenile OHT.
Perhitungan Laju Aliran Massa Air Pada Unit Cooling Tower di Area Utility A-1 PT.XYZ
Authors: Nugraha M. Alfi 
Published: December 2023

Unit utility mengelola dan menyediakan sarana untuk menunjang unit-unit lain dan berfungsi juga untuk mengawasi kelancaran proses produksi dari suatu pabrik terutama unit cooling tower atau pendinginan air. Pada Mechanical Cooling Tower terlihat bahwa pendinginan air dibantu oleh kipas / van yang terletak di atas tower. Jadi udara panas yang menguap dalam cooling tower akan dihisap oleh van / kipas dan dikeluarkan ke atas.Cooling tower memanfaatkan air dan udara pada proses perpindahan panas yang dibuang ke atmosfer. Kinerja cooling tower dievaluasi untuk mencari kinerja yang optimal dalam mensirkulasikan system pendinginan pada cooling tower dengan membandingkan data teori dengan data aktual berdasarkan perhitungan-perhitungan. Pada penelitian ini, akan diteliti hasil nilai laju aliran massa air. Dari beberapa parameter data seperti suhu aliran masuk dan keluar, kelembaban udara, kecepatan udara yang keluar blower, akan dicari laju aliran massa air yang ada pada cooling tower.setelah dilakukan penelitian dapat disimpulkan bahwa Laju aliran massa pada hari pertama adalah sebesar 12,70 Kg/s, hari ke-2 sebesar 13,2 Kg/s, hari ke-3 sebesar 10,78 Kg/s, dan hari ke-4 sebesar 10,55 Kg/s.
«Speak in the language that is appropriate for Russia»: the election of the Armenian Catholicos in 1866 in the travel journal of M.E. Chilyaeva
Authors: Урушадзе А.Т. 
Published: December 2023

В статье представлена публикация путевого журнала статского советника М.Е. Чиляева, который в сентябре 1866 г. принимал участие в выборах армянского католикоса в качестве российского наблюдателя. Журнал М.Е. Чиляева содержит ценные сведения о российской правительственной политике в отношении Армянской церкви, политических настроениях армянского духовенства. Отдельного внимания заслуживают оценки и мнения М.Е. Чиляева, в том числе его убежденность в необходимости более жесткой линии по отношению к турецким армянам. Журнал М.Е. Чиляева был известен в правительственных кругах, а некоторые его положения продолжали обсуждаться в дискуссиях по «армянскому вопросу» во второй половине XIX – начале XX в.
The article presents the publication of the travel journal of State Councilor M.E. Chilyaev, who in September 1866 took part in the elections of the Armenian Catholicos as a Russian observer. Journal M.E. Chilyaev contains valuable information about the Russian government policy towards the Armenian Church, the political sentiments of the Armenian clergy. The assessments and opinions of M.E. deserve special attention. Chilyaev, including his conviction in the need for a tougher line towards the Turkish Armenians. Journal M.E. Chilyaev was known in government circles, and some of his provisions continued to be discussed in discussions on the “Armenian question” in the second half of the 19th – early 20th centuries.
Consul General in Jerusalem Alexander Yakovlev. Biographical materials
Authors: Георги Ф.В. 
Published: December 2023

В статье комплексно рассматривается биография выдающегося дипломата, драгомана и востоковеда Александра Гавриловича Яковлева (1854–1909), посвятившего свою профессиональную жизнь укреплению русского присутствия и влияния в Святой земле. В 1879-1897 гг. он служил на разных должностях в российском консульстве в Иерусалиме и посольстве в Константинополе. В 1897-1907 гг. - генеральным консулом в Иерусалиме. На этом посту он сыграл значимую роль в деле защиты российских интересов и расширении материальной основы российского присутствия в Палестине. Заключительный этап своей жизни (1908-1909) провёл на посту министра–резидента (главы миссии) в Сиаме. Наследие А.Г. Яковлева актуально и сегодня. Впервые в русскоязычном издании публикуются и описываются фотоматериалы, связанные с А.Г. Яковлевым, его семьёй и коллегами, из альбома сотрудников консульства Российской империи в Иерусалиме, который вёлся в 1858–1914 гг., а с 1949 г. хранится в Национальной библиотеке Израиля. Кроме того, в статье рассматривается «бангкокский период» дипломата. В качестве источников изучения деятельности А.Г. Яковлева использованы документы, хранящиеся в Архиве внешней политики Российской империи Министерства иностранных дел Российской Федерации, Государственном архиве Российской Федерации, Национальной библиотеке Израиля.
The article comprehensively examines the biography of the outstanding diplomat, dragoman, and orientalist Alexander Gavrilovich Yakovlev (1854–1909), who devoted his professional life to strengthening the Russian presence and influence in the Holy Land. In 1879-1897 he served in various positions at the Russian Consulate in Jerusalem and the Embassy in Constantinople. In 1897–1907 worked as Consul General in Jerusalem. During his tenure Alexander Yakovlev played a significant role in protecting Russian interests and expanding the material basis of the Russian presence in Palestine. He spent the final stage of his life (1908–1909) as Resident Minister (head of mission) in Siam. The legacy of Alexander Yakovlev is still relevant today. For the first time in a Russian-language edition, photographic materials related to Alexander Yakovlev, his family, and colleagues, from the Album of employees of the Consulate of the Russian Empire in Jerusalem, which was managed in 1858–1914, and since 1949 has been kept in the National Library of Israel. In addition, the article describes the "Bangkok period" of the diplomat. As historical sources for studying the activities of Alexander Yakovlev, documents stored in the Archive of the Foreign Policy of the Russian Empire of the Ministry of Foreign Affairs of the Russian Federation, the State Archive of the Russian Federation, the National Library of Israel have been used.
Representasi Pria Metroseksual pada Iklan OVO-Tokopedia Edisi Playcoy
Authors: Sitti Nurhaliza Wa Ode , Puspita Ratna , Dwi Lestari Pipit 
Published: December 2023

Penelitian ini bertujuan untuk menganalisis representasi pria metroseksual dalam iklan OVO-Tokopedia edisi Playcuy. Tujuan penelitian ini untuk mengeatahui level realitas, level representasi dana level ideologi pria metroseksual direpresentasikan dalam video iklan OVO-Tokopedia Edisi Playcoy. Dengan menggunakan analisis semiotika John Fiske, peneliti ini mengungkapkan apa yang ingin disampaikan iklan OVO-Tokopedia sedisi Playcuy melalaui tokoh pria metroseksual. Hasil yang diperoleh menunjukkan Level realitas pada representasi pria metroseksual pada iklan OVO-Tokopedia edisi Playcuy. Dalam iklan ini pria metroseksual menonjolkan cara berpakaian trendi yang digambarkan melalui aksesoris yang melengkap di tokoh pria. Realitas yang ditampilkan dalam iklan OVO-Tokopedia edisi Playcoy menggambarkan pria pekerja, sukses, narsis dan percaya diri. Hal ini teridentifikasi dari penampilan, kostum, perilaku hingga gesture serta ekspresi tokoh pria. Selanjutnya, level representasi terdapat dua bagian yakni kode teknis dan representasi konvensional. Kode teknis seperti pengambilan gambar dan lighting. Pengambilan gambar menggunakan teknis close up, medium long shoot dan long shoot. Terkahir, level ideologi dalam iklan OVO-Tokopedia edisi Playcuy merepresntasikan pria metroseksual. Hal ini ditunjukan melalui tampilan yang dibaluti kdoe verbal dan nonverba. Secara iklan ini merepresentasikan pria metroseksual yang konsumnerime, kapitalisme dan narsisme. Ketiga hal tersebut muncul dalam iklan OVO-Tokopedia edisi Playcuy.
The Failed Alliance: Oliver Cromwell and the Great Conde
Authors: Ivonina Ludmila 
Published: December 2023

The bloody Thirty Years' War turned into a «European civil war», which part were the «parallel» civil upheavals in England and the Fronde in France. This period’s diplomacy was distinguished by particular complexity, inconsistency and a bizarre interweaving of state, social and personal interests.The relationship between
the head of the English Republic, Oliver Cromwell, and the French prince, Louis de Condé, organically fits into it.The article examines the course and results of the indirect dialogue between the two political leaders.Negotiations between them took place along several lines: the conclusion of a marriage between the heir to Condé and the daughter of Cromwell, about the possibility for the rebellious prince to become the French king, about obtaining mutual support, and even about the new religious and political state of Europe.The nature of the negotiations was determined by
the timing and balance of power in Britain, France and on the Continent.With regard to the Fronde of Princes and the Spanish Fronde, the English leader adopted a waiting tactic, skillfully intervening in relations between the French government and the
opposition.The interests of the state required an alliance with a stable France to fight against Spain.At that time,Condé, waiting for help from England, was guided, first of all, by personal interests and did not want to compromise.As a prince of the blood, he, while admiring Cromwell, still put him below himself.
Study of interface-trap and near-interface-state distribution in a 4H-SiC MOS capacitor with the full-distributed circuit model
Authors: Van Cuong Vuong , Koyanagi Kaho , Meguro Tatsuya , Ishikawa Seiji , Maeda Tomonori , Sezaki Hiroshi , Kuroki Shin-Ichiro 
Published: December 2023

Abstract
In this research, the full-distributed circuit model was used to classify the contribution of interface traps (ITs) and near-interface states to the electrical characteristics of a 4H-SiC MOS capacitor over a wide range of operation. By fitting the measured capacitance and conductance at a certain value of applied gate voltage when the frequency varied from 1 kHz to 1 MHz, the density of both near-interface states and ITs was determined. The results reveal that, at RT, the frequency dispersion of capacitance in the depletion condition is mainly caused by the contribution of ITs. Nevertheless, in the strong accumulation condition, near-interface states become dominant for the frequency dispersion of the capacitance. Furthermore, the full-distributed circuit model also successfully explained the electrical characteristics of a 4H-SiC MOS capacitor when operating at 500 °C.