bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimalisasi Strategi Pemasaran Melalui Media Sosial bagi UMKM Kopi Dadaman Desa Citaman Banten
Authors: Fadhilah Fadhilah , Satyanegara Diqbal , Pertiwi Widya Nur Bhakti 
Published: December 2023

<p><em>UMKM (Usaha Mikro, Kecil, dan Menengah) merupakan salah satu pilar perekonomian Indonesia yang memiliki kontribusi besar terhadap PDB nasional. Kopi Dadaman merupakan</em> <em>salah satu UMKM yang memiliki potensi besar di Desa Citaman Kecamatan Ciomas, Kabupaten Serang, Provinsi Banten. Kopi Dadaman yaitu produk kopi robusta yang diproduksi menggunakan biji kopi yang langsung ditanam di desanya. Namun, banyak kendala yang dihadapi oleh para pelaku UMKM Kopi Dadaman, diantaranya yaitu produk yang dimiliki belum menjangkau pasar luas karena belum mengoptimalkan media sosial sebagai alat pemasarannya. Padahal, media sosial telah terbukti dapat mem</em><em>p</em><em>engaruhi konsumen dalam proses keputusan pembelian. Tujuan dari program pengabdian ini adalah untuk meningkatkan keterampilan para pelaku UMKM Kopi Citaman, khususnya yaitu dalam menggunakan media sosial Instagram dan WhatsApp Business sebagai alat pemasaran untuk menjangkau pasar lebih luas dan meningkatkan penjualan produk. Whatsapp dan In</em><em>s</em><em>tagram dipilih karena merupakan media sosial yang paling banyak digunakan oleh masyarakat Indonesia. Metode pelaksanaan kegiatan pengabdian ini adalah dengan memberikan pelatihan pengelolaan aplikasi WhatsApp Business</em><em> dan </em><em>pelatihan pengelolaan media sosial Instagram.</em><em> Luaran yang dihasilkan dalam program pengabdian ini adalah akun Instagram Business dan WhatsApp Business dari Kopi Dadaman serta keterampilan para pelaku usahanya dalam pengelolaan fitur-fitur pada kedua media sosial tersebut untuk meningkatkan penjualan.</em></p><p><strong>Kata kunci<em>:</em></strong><strong><em> </em></strong><strong><em>UMKM, Instagram, Whatsapp Business, Kopi</em></strong></p>
Enzymatic Indicators in Vaporized Hydrogen Peroxide Decontamination Cycles: Application-related Research focusing on Fractional Kill Time (FKT) and Reverse Fractional Kill Time (RFKT) Studies
Authors: Scharf Birte , Gole Marina , Kötter Marcel 
Published: December 2023

The accepted standard from a regulatory perspective for vaporized hydrogen peroxide (vH2O2) cycle validation is the use of biological indicators (BIs). Novel enzymatic indicators (EIs) are gaining more importance in this field, relying on specific enzymatic reactions for their functionality. The aim of this work is to determine how enzymatic indicators can contribute to the cycle development process. Emphasis was placed on the initial informative study, the fractional kill time study, which is a basis for future studies. The results indicate that enzymatic indicators have the potential to facilitate further development of the cycle. This requires an analysis of the determined data, measured in relative light units (RLU), and aligning it with the BI growth, resulting in Full Kill/ No Kill limits. The use of enzymatic indicators for decontamination cycle development opens new perspectives and holds considerable potential for practical use in the development and validation of decontamination processes.
Sexy tools: Individual differences in drumming tool shape
Authors: Klump Barbara C. 
Published: December 2023

SummaryHeinsohn et al. Proceedings of the Royal Society B, 290, 2023.1271, (2023) report that the choice of tool type (drumsticks or seed pods) and the shape of drumsticks manufactured by palm cockatoos differ among individuals. This variation does not seem to be culturally transmitted as no spatial correlation between proximity of display trees and tool shape was found.
Fulminant Myocarditis Mimicking Myocardial Infarction in a Young Woman: A Challenging Diagnosis and Treatment
Authors: Bahar Mokhamad Aswin , Karolina Wella , Rohman Mohammad Saifur , Anjarwani Setyasih , Prasetya Indra 
Published: December 2023

BACKGROUND: Fulminant myocarditis is a rare and serious condition with high mortality. It poses diagnostic challenges due to myocardial infarction-like symptoms and rapid deterioration. Timely diagnosis and access to advanced interventions are vital for optimal management and improved outcomes.
CASE PRESENTATION: A 34-year-old woman presented with typical chest pain, ST changes, positive cardiac biomarkers, and impaired left ventricle function. The presumptive diagnosis was fulminant myocarditis complicated with cardiogenic shock, respiratory failure, and acute kidney injury. Leukocytosis and high anti-streptolysin O (ASO) titer suggested a recent streptococcal infection as a possible cause. Advanced intervention limitations hindered patient management. On the second day, the patient had a cardiac arrest.
CONCLUSION: The diagnosis can be challenging due to the similarity of symptoms and signs to myocardial infarction, combined with the rapid deterioration of the patient’s condition. Prompt initiation of mechanical circulatory support is vital. However, its limited availability in developing countries hinders routine implementation, leading to unfavorable outcomes when life support measures are unavailable.
Leçons d’agilité de la part d’un spécialiste de l’urgence
Authors: Gallet Jean-Claude 
Published: December 2023

Afin de rendre les sapeurs-pompiers de Paris plus agiles face à l’imprévu, Jean-Claude Gallet a participé à l’élaboration de nouvelles doctrines et pratiques. Il témoigne de l’effet de ces dernières dans la gestion de crises majeures : les attentats de 2015 et l’incendie de Notre-Dame de Paris .
Diagnosis and management of Wilson’s disease: Current perspectives
Authors: Pachipala Sudheer , Agarwal Ayush , Garg Divyani , Garg Ajay , Srivastava Achal K 
Published: December 2023

AbstractWilson’s disease (WD) is an autosomal recessive disease caused by mutations in theATP7Bgene on chromosome 13q. The clinical manifestations of WD are varied and occur due to copper accumulation in organs such as the liver and brain. Although there are various laboratory findings and radiological signs suggestive of WD, they are non-specific and can be abnormal in various clinical conditions. If left untreated, the disease is fatal; therefore, early diagnosis and treatment is of utmost importance. Although several guidelines have been formulated, a clear management consensus is lacking. We performed a comprehensive literature search using the PubMed database before November 1, 2022, to extract relevant information for this narrative review with the aim of providing updates on the diagnosis and management of WD.
Three-dimensional Assessment of Temporomandibular Joint Volume, and Condylar and Glenoid-fossa Morphology: A Cone-beam Computed Tomography Study
Authors: Mehta Shivam , Gandhi Vaibhav , Patel Apexa , Chen Po-Jung , Lin Meng-Hsuan , Kuo Chia-Ling , Tadinada Aditya , Yadav Sumit 
Published: December 2023

Background:
The condylar and glenoid fossa morphology can alter in patients with temporomandibular disorders (TMD), which can lead to changes in the temporomandibular joint (TMJ) space volume. Volumetric evaluation of TMJ can represent the entire three-dimensional (3D)-joint space between the condyle and glenoid fossa.

Aims:
To perform 3D assessment of TMJ volume, condylar, and glenoid-fossa morphology using cone-beam computed tomography and evaluate the correlation between these parameters.

Settings and Design:
Thirty-four patients (age: 13.50 years) who had no previous history of TMD were included.

Materials and Methods:
The volume of TMJ space was measured and divided into anterior, posterior, medial, and lateral TMJ volume. The antero-posterior (AP) and medio-lateral (ML) condylar width, AP and ML glenoid-fossa width, and glenoid-fossa depth were evaluated.

Statistical Analysis Used:
Statistical analyses were performed with R software at a 0.05 significance level. Each parameter was compared between the left and right sides using a paired-t test. The correlations between the parameters were obtained by the Pearson correlation coefficient.

Results:
There was no significant difference between lateral and medial TMJ volume; however, posterior TMJ volume was significantly greater than anterior TMJ volume. A significant correlation was observed between AP glenoid-fossa width and TMJ volume, glenoid-fossa depth and TMJ volume, AP position of the condyle and anterior TMJ volume, ML position of the condyle and medial TMJ volume, glenoid-fossa width and condyle width in AP and ML dimension, glenoid-fossa depth and AP glenoid-fossa width.

Conclusions:
In addition to the evaluation of condylar and glenoid-fossa morphology, assessment of TMJ space volume is important for comprehensive evaluation of the joint.
Subclinical hypothyroidism and anti-thyroid peroxidase antibodies in primary open-angle glaucoma: A case–control study
Authors: Unnikrishnan Suma , Anilakumari VP , Mohammed Ferzana 
Published: December 2023

Purpose:
To evaluate the association among subclinical hypothyroidism, anti-thyroid peroxidase (anti-TPO) antibody, and primary open-angle glaucoma (POAG).

Study design:
Case–control study.

Methods:
The cases consisted of patients with POAG and controls were age- and sex-matched patients from the general eye clinic with no history of glaucoma. Blood samples were taken from the participants’ antecubital veins and sent for measurement of thyroid stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), and anti-thyroid peroxidase (anti-TPO) antibody. Data was analyzed using the Mann–Whitney U test and the Chi-square test. Odds ratio with 95% confidence interval (CI) was calculated. A two-tailed P value less than 0.05 was considered for statistical significance.

Results:
There were a total of 63 cases and 63 controls. Subclinical hypothyroidism was present in 20.6% of patients in the glaucoma group and 4.8% of patients in the control group (P < 0.01). The odds of subclinical hypothyroidism in patients with POAG compared to controls was 5.2 (95% CI 1.7–22). Anti-TPO antibody positivity was higher in the glaucoma group (22.2%) than in the control group (14.3%), but this did not reach statistical significance (P = 0.25).

Conclusion:
This study suggests an association between POAG and subclinical hypothyroidism. Further research is needed to establish the cause-and-effect relationship between these two conditions.
Newborn screening for congenital hypothyroidism, congenital adrenal hyperplasia and glucose-6-phosphate dehydrogenase deficiency in Bihar: A pressing priority in today's time
Authors: Kumari Bandana , Raj Khushboo , Sharma Sadhana , Kumar Sushil , Chowdhry Bhabesh K. , Kumar Amit 
Published: December 2023

Background and Objective:Newborn screening (NBS) aims towards early detection of congenital disorders or prevention of intellectual and physical defects and life-threatening illness. Three disorders namely congenital hypothyroidism (CH), congenital adrenal hyperplasia (CAH) and glucose-6-phosphate dehydrogenase deficiency (G-6-PDD) were selected for a preliminary study for NBS. The study aimed to establish NBS in the Indian scenario that could lay a framework for future such initiatives.Methods:A screening programme was conducted at a tertiary care hospital for 1 year. All the neonates born at All India Institute of Medical Sciences (AIIMS), Patna, were screened for their blood levels of glucose-6-phosphate dehydrogenase (G-6-PD), 17-hydroxyprogesterone (17-OHP) and thyroid-stimulating hormone (TSH). Heel-prick blood samples were collected within 48–72 h of birth, and the level of these parameters was accessed by enzyme immunoassay (EIA).Results:A total of 492 neonates were born from January 2020 to December 2020, of which 369 newborns were screened for CAH, CH and G-6-PDD. Of 369 neonates, one case (male) had an increased level of TSH, six cases (all males) had an increased level of 17-OHP and no case was found with G-6-PDD.Interpretation and Conclusions:Preliminary data on the prevalence of various genetic disorders revealed that CAH is the most prevalent disorder followed by CH in the population of Bihar. More efforts need to be undertaken to create awareness and to make screening a successful programme in India. A cost-effective nationwide screening programme is highly recommended for the detection of such cases at the earliest to avoid their future complication.
Phenotypic characterization and antifungal susceptibility profile of Candida isolates from women with vulvovaginal candidiasis at a community health center linked to a teaching institution in the Sub-Himalayan region of North India
Authors: Rawat Sangeeta , Singh Rajender , Mittal Garima 
Published: December 2023

Introduction:
Vulvovaginal candidiasis (VVC) is considered a common gynecological problem among females of reproductive age group. 70–75% of women report having had candidal vulvovaginitis at some point in their lifetimes and 40–50% suffer recurrent candidal vulvovaginitis.

Objectives:
This study aims to identify the Candida species involved in VVC and to determine their antifungal susceptibility pattern.

Materials and Methods:
The present study was a cross-sectional study conducted on 257 females (18–55 yr) with complaints of abnormal vaginal discharge. For detection of Candida, the swab samples were subjected to Gram stain, 10% KOH mount, and culture on Sabouraud dextrose agar (SDA). Candida species identification was done by subculturing Candida isolates onto CHROMagar, corn meal agar (Himedia), and further confirmation was done by MALDI-TOF MS. Antifungal testing was done using the disk diffusion method.

Results:
A total of 257 females with complaints of abnormal discharge were enrolled in this study. Out of 257, C. albicans 37 (58.7%) and 26 (41.3%) isolates were identified as non-albicans Candida. Out of 63 positive cases, a maximum number of study subject belongs to the age group 26–35 years (50.8%). Along with vaginal discharge, itching (65.37%) is the most common complaint. VVC was found to be most predominant in patients with prolonged antibiotic therapy (38.1%), and in pregnant females (15.9%).

Conclusion:
Understanding the emerging fungal pathogens and their drug susceptibility patterns is essential for the effective management of infections. Drug resistance can lead to treatment failure and highlights the need for alternative treatment options or strategies.
Examining corporate support issues with health literacy as a key factor: The Case of a Hiroshima corporation
Authors: Li Yuan , Kawasaki Hiromi , Yamasaki Satoko , Nakaoka Sae , Shiraishi Misa , Cui Zhengai 
Published: December 2023

Context:Given the dramatic decline in Japan's labor force, promoting women's participation in the workforce is essential.Aims:We aimed to take a Hiroshima company as an example and analyze the influencing factors of health literacy (HL) to clarify the issues of the active participation of female employees.Methods and Materials:From February to March 2023, a cross-sectional study was conducted by a company in Hiroshima prefecture that contained many male employees. A total of 1,114 valid respondents were received. Employees' demographics, menstrual-related concerns, women's activity promotion support, and HL were investigated in this study.Statistical Analysis Used:The Chi-square test and logistic regression using SPSS statistical software version 25 were used.Results:There were significant differences between high and low HL with age, women's menstrual problems, and women's activity promotion support. The participants who were unaware of women's menstrual-related problems and their company's implementation of women's activity promotion support were more likely to have high HL. In addition, female employees (including female management) and male management have significantly different cognitions about women's activity promotion support.Conclusions:This study found that overall HL among employees in male-dominated companies is low, even among participants who were aware of women's menstruation-related health issues and the company's women's activity promotion support. Increased women's representation in management can bridge policy perception gaps. Male-dominated companies should enhance HL via career programs, health education, and improved communication for active female engagement.
Gap identification for improvement in maternal and early infant health care practices among tribal pregnant women in an aspirational tribal district Sirohi, Rajasthan
Authors: Dwivedi Rakhi , Goel Akhil D. , Vyas Varuna , Yadav Suraj S. , Sharma Prem P. , Bhardwaj Pankaj , Singh Pratibha , Singh Kuldeep 
Published: December 2023

Background:Sirohi is one of the aspirational districts of Rajasthan which is also tribal-dominated. The maternal and early infant health indicators are worrisome compared to regional or national statistics. First-trimester registration of pregnant women is 54% in district Sirohi, which is much less as compared to registration in the state of Rajasthan (63%) and India (59%). Four antenatal care (ANC) visits of pregnant women are 32% in district Sirohi, which is also much less as compared to ANC visits in the state of Rajasthan (39%) and India (51%). However, there was no tribal-specific data regarding maternal and early infant health.Objective:The study aims to identify gaps for improvement in maternal and early infant health care practices among tribal pregnant women in an aspirational tribal district of Sirohi, Rajasthan.Materials and Methods:It was a cross-sectional study conducted among 560 tribal pregnant women to assess the existing maternal, and early infant health care knowledge and practices through a pre-validated questionnaire in the tribal population of district Sirohi Rajasthan.Result:Nineteen per cent (19.5%,n= 109) of tribal pregnant women got married between the age of 10 and 17 (less than the legal age of marriage of 18 years). There is a significant relationship between early age at marriage and low educational statusP< 0.001,r= 0.241 among participants. Measurement of weight, blood pressure and urine examination was done in 32.5% (n= 181), 19.5% (n= 109) and 7.1% (n= 39), respectively, among tribal pregnant women. The majority (94.6%) of the pregnant tribal women (385/407) were anaemic. Approximately 60% (n= 337) of mothers were unaware of thermal protection (skin-to-skin care). Sixty per cent (n= 334) of tribal pregnant women preferred to seek consultation regarding antenatal and infant health care from doctors, while 40.1% (n= 224) were more comfortable seeking advice from traditional birth attendants (TBAs).Conclusion:The study finds inadequate knowledge and practice towards maternal and early infant care among tribal pregnant women. As TBAs influence tribal pregnant women, systematic training and involvement of TBAs in maternal and child health are indispensable.
Comparison of the efficacy of intravenous labetalol versus oral nifedipine in patients with severe pregnancy-induced hypertension beyond 30 weeks of gestation
Authors: Agarwal Manika , Rukshana Makakmayum , Basu Ritisha , Shullai Wansalan K. , Singh Santa A. 
Published: December 2023

Hypertensive disorders of pregnancy affect 5% to 10% of all pregnancies globally. The aim of treatment is to bring down blood pressure (BP) quickly and smoothly, which is safe for the mother and baby. The aim of our study was to study the efficacy and safety of intravenous labetalol and oral nifedipine in severe pregnancy-induced hypertension.

Materials and Methods:
It is a retrospective observational study, intravenous labetalol 20 mg was given initially in escalating doses of 40 mg, 80 mg, 80 mg, and 80 mg every 15 mins up to a maximum dose of 5 or until the goal BP ≤150/100 mmHg was reached. Some women with severe pregnancy-induced hypertension were given oral nifedipine to control their BP according to the choice of the attending consultant. Nifedipine 10 mg tablet was given initially in repeated doses of 10 mg every 15 mins up to a maximum of five doses or until the goal of BP ≤150/100 mmHg was reached.

Results:
In our study, we found that there was a strong statistical significance in stabilizing the BP with oral nifedipine than with intravenous labetalol drug used. The majority of the patients in the oral nifedipine group got to normal BP quicker when compared to intravenous labetalol group patients.

Conclusion:
From this study, both drugs were found to be safe and effective in the reduction in BP. The use of nifedipine may be recommended in low-resource settings since it has an oral regimen and dosage is simple when compared to incremental intravenous dosing of labetalol.
Assessment of health-related quality of life and its determinants among COVID-19 intensive care unit survivors
Authors: Neelima Mariyala , Chivukula Satya K. 
Published: December 2023

Background:Health-related quality of life (HRQoL) is a multidimensional concept encompassing the physical, functional, emotional, and social/family well-being of an individual. Recent reports suggest that Covid-19 may lead to poorer HRQoL of the patients infected both in the short and long term. The present study aimed to assess the health-related quality of life and their determinants among COVID-19 intensive care unit (ICU) survivors.Materials and Methods:In the study, 107 COVID-19 (RTPCR positive) patients admitted to the (ICU) of a tertiary care centre from August 2021-January 2022 were taken from the hospital records. Line listing of all the patients was done, and the study population was selected using the lottery method under a simple random sampling method. The study population was contacted by telephone and requested their willingness to participate in the study. EQ-5D-5L was used to assess quality of life, which is a standard instrument to assess HRQoL (developed by the EuroQol group in 2011). The EQ-5D-5L essentially consists of the EQ-5D descriptive system and the EQ visual analogue scale (EQ-VAS). Data entry was done using Microsoft excel 2019 version and data analysis using MedCalc version 20.015.Results:The mean EQ-5D-5L utility score was 0.51 ± 0.43. The mean EQ-VAS score was 68.97 ± 22.27. A significant association between co-morbidities and EQ-5D-5L utility score where those with co-morbidities had a lesser EQ-5D-5L score compared to those without co-morbidities. The mean duration of ICU stay in days was 12.29 ± 12.17. A significant negative correlation between the duration of ICU stay and EQ-5D-5L. (r = −0.26,P= 0.0006*).Conclusion:COVID-19 patients with comorbidities had a significantly poor quality of life. These findings may help healthcare professionals and decision-makers to better understand the consequences of COVID-19 on the HRQoL.