bluuebunny/crossref_metadata_2025_split huggingface dataset:
From Technology‐Challenged Teachers to Empowered Digitalized Citizens: Exploring the Profiles and Antecedents of Teacher AI Literacy in the Chinese EFL Context
Authors: Pan Ziwen , Wang Yongliang 
Published: January 2025

ABSTRACTArtificial Intelligence (AI) literacy has come to the spotlight, empowering individuals to adeptly navigate the modern digitalised world. However, studies on teacher AI literacy in the English as a Foreign Language (EFL) context remain limited. This study aims to identify intraindividual differences in AI literacy and examine its associations with age and years of teaching experience among 782 English teachers. Given the absence of a reliable instrument to measure teacher AI literacy, we first constructed and validated a scale encompassing five sub‐scales: AI Knowledge, AI Use, AI Assessment, AI Design, and AI Ethics. Subsequently, latent profile analysis (LPA) was conducted using Mplus 7.4, with the results revealing four distinct profiles: Poor AI literacy (C1: 12.1%), Moderate AI literacy (C2: 45.5%), Good AI literacy (C3: 28.4%), and Excellent AI literacy (C4: 14.1%). Multinomial logistic regression analyses indicated significant associations between teacher AI literacy and both age and years of teaching experience. Additionally, 32 respondents participated in semi‐structured interviews. The qualitative data analysed with MAXQDA 2022 triangulated the quantitative results and offered deeper insights into teachers’ perceptions of their AI literacy. This study provides both theoretical and practical implications for understanding teacher AI literacy in the Chinese EFL context.
A Brief Discussion of Research Philosophies for Higher Education Students
Authors: May Daniel E. 
Published: January 2025

ABSTRACTStudents developing their theses/dissertations can find it difficult to justify their methodologies from a philosophical perspective. The objective of this article was to provide guidance to higher education students and to help them to select the right philosophical framework for their chosen methodological approach. For this purpose, a simple and concise description of key research philosophies currently used for either qualitative, quantitative or mixed method research is provided.
Using High‐Resolution Fisheries Data to Identify Spatial Patterns in Retained Catch Compositions for Mixed Fisheries
Authors: Anastasi Gianfranco , Ball Johnathan , Martinez Roi L. , Dolder Paul J. 
Published: January 2025

ABSTRACTMixed fisheries exploit fish stocks that are heterogeneously distributed in space using gears that are not species selective. This poses a challenge for management as catch limits for less productive stocks constrain catches of more productive stocks leading to losses in yield and economic value. Decoupling catches of stocks caught together in mixed fisheries could increase potential yields and may be achieved through changes in spatial fishing patterns. This study identifies fine‐scale spatial patterns of retained catches for the UK otter trawlers in UK waters by combining vessel monitoring system positional information and logbook data on retained catches. Spatially contiguous units were identified through a combination of Principal Components Analysis and spatial clustering. Our results show a complex spatial structure in the fish assemblage which differs across UK sea areas, with greater similarity between the Northern North Sea and West of Scotland compared to other sea areas. Through simulation, we highlight how fine‐scale spatially resolved fisheries data can identify areas where choke risks from catches of low‐quota, low‐productivity species associated with target species can be reduced. This underscores the value of fine‐scale data for enhancing efficiency and sustainability in mixed fisheries. Wider benefits from the use of fine‐scale data include the ability to identify consistent spatial métier definitions for use in modelling technical interactions. Ultimately, our study informs strategies and approaches that decouple catches of low‐quota, low‐productivity species caught together in mixed fisheries, improving sustainability and the conservation of living resources under complex management challenges.
Engaging in transnational ways of teaching and building a community of practice: Preservice teachers’ experiences in an online after‐school program
Authors: Kwon Jungmin 
Published: January 2025

AbstractEmploying the concepts of transnational funds of knowledge and community practice, this ethnographic case study examines the experiences of preservice world language teachers in a year‐long teaching methods course. It focuses on an online after‐school program where preservice teachers taught languages and cultures to children from linguistically and culturally diverse backgrounds. The findings illustrate how a teacher candidate from a multilingual and immigrant background drew on her transnational lived experiences and encouraged students to think beyond the boundaries of languages, cultures, and countries. Findings also show how preservice teachers in the program learned from fellow teachers’ practices and built a shared repertoire of resources to engage in transnational ways of teaching language and culture. This study underscores the importance of providing clinical opportunities where preservice teachers can put theory into practice, incorporate transnational funds of knowledge that learners possess, and challenge linguistic, cultural, and geographic boundaries.
Haemophilia Infants Gross Motor Development: Comparisons With Full‐Term and Preterm Infants of the Same Nationality
Authors: Syrengelas Dimitrios , Dettoraki Athina , Michalopoulou Aikaterini , Kleisiouni Paraskevi , Siahanidou Tania , Moschou Christina T. , Kyprianou Miltiades A. , Peristeris Platon , Pergantou Helen 
Published: January 2025

ABSTRACTIntroductionInfants with haemophilia, due to parental overprotection, have difficulty developing their full motor repertoire of typical gross motor development. It is of great clinical importance to evaluate the motor development of these infants with a standardized assessment tool.AimTo study the gross motor development in infants with haemophilia, using the Alberta Infant Motor Scale (AIMS) and compare it with full‐term (FT) and preterm infants (PT).MethodsFifteen FT infants with severe or moderate haemophilia A and B were assessed with the AIMS (Group D). The scale is already standardized in FT Greek infants (Group A). Two groups of PT infants were also included, with gestational age >32 weeks and ≤32 weeks, Groups B and C, respectively. The mean Z‐scores were tested with the ANOVA procedure, followed by post hoc pairwise comparisons with Bonferroni correction.ResultsThe four groups had significantly different mean Z‐scores. Infants in Group A had a mean Z‐score of 0 ± 1. Infants in Group B lagged significantly behind by one standard deviation. Preterm infants in Group C had a mean Z‐score significantly lower than Group B. Infants in Group D had a mean Z‐score significantly lower than Group C.ConclusionsMotor development in infants with haemophilia significantly lags behind both FT and PT infants. Differences in AIMS scores could be attributed to the reduction of movement activity, since infants with haemophilia are often deprived of certain positions, being held and carried in the parents' arms, as well as from free play time on the floor.
Operationalising a Haemophilia Gene Editing Lexicon for Practical Use
Authors: McKeown William , Hermans Cedric , Unzu Carmen , Kay Mark A. , Peyvandi Flora , Smith Penni , Miesbach Wolfgang , Pierce Glenn F. , Khair Kate , Valentino Leonard A. , Pipe Steven W. , Pillai Monisha , Jones Micheala , Delwart Virginie , Sindhurakar Anil , Gutstein David E. , Kessler Craig M. 
Published: January 2025

ABSTRACTIntroductionGene editing therapies offer the possibility of substantial improvement in treatment and quality of life for people with haemophilia (PWH) in a landscape of dynamic therapeutic advancement. Developing a common and understandable language to discuss gene editing will be essential to ensure these treatments can be deployed in a safe and effective manner with fully informed and shared decision‐making between healthcare professionals (HCPs) and PWH. A lexicon explaining and clarifying key concepts is one potential tool to address these aims. Here we evaluate how a gene editing lexicon could be deployed to maximise impact and improve patient outcomes.AimTo operationalise the gene editing lexicon for successful adoption by the haemophilia community.MethodsThrough an innovative, iterative process, representatives from the haemophilia community, including multidisciplinary HCPs, PWH, and caregivers, with support from language strategy experts, developed a gene editing lexicon and evaluated operational aspects for real‐world adoption of this resource.ResultsA gene editing lexicon was developed, including infographics illustrating key concepts. Infographics were adapted from the lexicon to further clarify and communicate these concepts. Infographics were found to be a potentially vital tool for enhancing the practical use of the lexicon to promote shared decision‐making and attain informed consent for gene editing therapies.ConclusionA gene editing lexicon shows promise for improving the understanding of gene editing for all stakeholders in the haemophilia community. Ensuring the lexicon remains up to date with current therapies and appropriate strategies for adoption such as infographics will enable this resource to have maximum impact.
Should Metronidazole Be Included in Second‐Line Treatment After Standard Triple Therapy for Helicobacter pylori?: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials
Authors: Mori Hideki , Nishizawa Toshihiro , Morioka Kohei , Kato Motohiko , Kanai Takanori 
Published: January 2025

ABSTRACTBackground and AimAlthough standard triple therapy remains the first‐line eradication treatment for H. pylori worldwide, it is unclear whether metronidazole should be included empirically in second‐line eradication treatments. The aim of this study was to compare the efficacy of metronidazole‐containing regimens with that of metronidazole‐free regimens after failure of first‐line eradication using standard triple therapy.MethodsPubMed, the Cochrane Library, and the Igaku‐Chuo‐Zasshi database were searched to identify RCTs eligible for inclusion in this systematic review and meta‐analysis. Odds ratios (ORs) with 95% confidence intervals (CIs) were calculated.ResultsThirteen eligible RCTs were included, with a total of 2039 patients assigned to metronidazole‐containing (975 patients) or metronidazole‐free (1064 patients) regimens. Metronidazole‐containing regimens had significantly lower eradication failure rates than regimens without metronidazole (OR 0.55; 95% CI, 0.39–0.78). Subgroup analysis based on the regional risk of metronidazole resistance demonstrated that metronidazole‐containing regimens had lower eradication failure rates not only in low‐risk regions but also in high‐risk regions (OR, 0.29; 95% CI, 0.11–0.74 and OR, 0.66; 95% CI, 0.49–0.91, respectively).ConclusionAfter failure of standard triple therapy, secondary eradication treatment regimens containing metronidazole demonstrate higher eradication rates than those without metronidazole.
Acute Nonsustained Mitral Isthmus Block Obtained With Sphere‐9 Lattice‐Tip Catheter Completed With Vein of Marshall Ethanol Infusion
Authors: Kneizeh Kinan , Vlachos Konstantinos , Monaco Cinzia , Jaïs Pierre , Pambrun Thomas , Derval Nicolas 
Published: January 2025

ABSTRACTBackgroundAchieving a durable mitral line block using radiofrequency as a part of an anatomical approach for ablation in patients with persistent atrial fibrillation or for treating peri‐mitral flutter has always been challenging due to the complex anatomy of the mitral isthmus. Epicardial ablation via the coronary sinus and the vein of Marshall has been proposed to help create durable lesions. Recently, a novel lattice‐tip catheter using pulsed field ablation has shown promising results for creating mitral lines, despite limited data.Methods and ResultsWe present a case demonstrating the recovery of connection through the mitral isthmus after a waiting period, despite initial clear isolation achieved by creating an endocardial linear lesion. This necessitated further epicardial lesions, performed via ethanol infusion into the vein of Marshall, due to the presence of a coronary sinus CRT lead in this patient.ConclusionDespite the high rates of acute mitral line block with PFA the rate of recurrence might be significant. Considering its novelty, our experience with point‐by‐point PFA is more limited. The present case report highlights the risk of delayed reconnection treated with EI‐VOM. Further studies are warranted to explore additional outcomes and recurrence patterns among these patients.
The long reach of adversity: Intermediary pathways from maternal adverse childhood experiences to child socio‐emotional and cognitive outcomes
Authors: Madigan Sheri , Plamondon André , Jenkins Jennifer M. 
Published: January 2025

BackgroundThis longitudinal study with multi‐informant (maternal, paternal, and experimenter) and multimethod (questionnaires, behavioral observations, and standardized assessments) data tests an intergenerational model from mothers' adverse childhood experiences (ACEs) to their children's socio‐emotional and cognitive outcomes.MethodsParticipants were 501 children (50.7% male) and caregivers (56.5% white) followed from child age 2 months to 5 years. Mothers reported on their ACEs, as well as their postnatal socio‐economic status (SES), marital conflict, and depressive symptoms. Observers rated maternal sensitivity using validated coding systems. Partners' history of childhood conduct problems and children's emotional and conduct problems were rated by mothers and fathers, and cognition was assessed by experimenters using standardized assessments.ResultsMaternal ACEs score was associated with children's socio‐emotional and cognitive outcomes through unique intermediary pathways. Specifically, maternal ACEs were related to child emotion problems through SES, paternal history of conduct problems, and maternal depression. Maternal ACEs to child conduct problems operated via SES, paternal history of conduct problems, and marital conflict. Maternal ACEs to child cognitive skills operated through SES and maternal sensitivity.ConclusionsMaternal ACEs, economic stress, and paternal history of conduct problems may collectively strain families, diverting caregiver attention and resources, which may impact childrearing and children's development. To effectively address root causes of intergenerational risks, it is critical to advocate for resources and supports that mitigate these hardship conditions. In addition, interventions that target modifiable individual and family factors may hold the greatest promise for breaking cycles of generational risk and promoting healthier outcomes for children and families.
Improving Patient Reported Outcome Measure Collection Through Increased Patient Outreaches: Utilization of a Return‐to‐Work Program
Authors: Schmitt Stacy L. , Ford Sasha R. , Pisati Tejaswini , Springsted Martha L. , Mauck William D. , Hardesty Kevin G. , Tiegs‐Heiden Christin A. 
Published: January 2025

ABSTRACTRationalePatient reported outcome (PRO) measures are a critical tool to understand the patient's experience of their illness. Our institution collects PRO measures for patients receiving spine care through several modalities, including direct patient outreaches.Aims and ObjectivesWe designed a quality project to increase the total number of patient outreaches within 1 year, without increasing program resources or costs, by utilizing a return‐to‐work program.MethodSpine PRO collection rate data was extracted from the electronic health record by a data science analyst. This data included how many direct patient outreaches were completed each month and the average number of patient outreaches being completed by the patient outreach representative. For the balancing measure, full‐time equivalent costs were monitored throughout the baseline and pilot periods.ResultsDuring the 6‐month baseline period, 3477 patient outreaches were made, representing 14.5% of possible outreaches. During the first 3‐month post‐intervention remeasure period, 6272 patient outreaches were made, an increase of 55.44%. During the second 3‐month post‐intervention period, 9099 outreaches were made, an increase of 38.21% from the first remeasure. There was no increase in cost to the program related to the project.ConclusionThis increase in patient outreaches by return‐to‐work employees will translate to improvement in overall PRO collection rates, which may ultimately improve individual and population health care delivery.
Current Landscape of Adoptive Cell Therapy and Challenge to Develop “Off‐The‐Shelf” Therapy for Hepatocellular Carcinoma
Authors: Shin Seung Kak , Mishima Yuta , Lee Yoonseok , Kwon Oh Sang , Kim Ju Hyun , Kim Yun Soo , Kaneko Shin 
Published: January 2025

ABSTRACTAdoptive cell therapy (ACT) is a type of immunotherapy in which autologous or allogeneic immune cells, such as tumor‐infiltrating lymphocytes or engineered lymphocytes, are infused into patients with cancer to eliminate malignant cells. Recently, autologous T cells modified to express a chimeric antigen receptor (CAR) targeting CD19 showed a positive response in clinical studies for hematologic malignancies and have begun to be used in clinical practice. This article discusses the current status and promise of ACT research in hepatocellular carcinoma (HCC), focusing on challenges in off‐the‐shelf ACT using primary cells or induced pluripotent stem cells (iPSCs) with or without genetic engineering. Early clinical trials of autologous GPC‐3‐, MUC1‐, or CEA‐targeted CAR‐T cell therapies are underway for HCC. There is a growing demand for the development of off‐the‐shelf therapies due to the high cost and manufacturing issues associated with autologous CAR‐T. The development of ACT from various cell sources, such as NK cells, NKT cells, macrophages, and γδ T cells without MHC restriction other than T cells has been proposed. Advances in genome editing, including HLA gene knockout to avoid GvHD, and strategies to enhance efficacy in overcoming the suppressive tumor microenvironment, are used to create universal ‘off‐the‐shelf’ CAR‐T cells which can be used immediately as therapeutic products from healthy donors or iPSC‐derived immune cells. Despite several limitations, cell‐based immunotherapy is expected to become a key cancer treatment modality for both hematologic malignancies and solid tumors including HCC, thanks to technological advancements overcoming these challenges.
Triple bottom line analysis of the decline in foreign tourist demand in Japan due to the COVID‐19 pandemic: Counterfactual structural decomposition approach
Authors: Oga Yusuke , Kagawa Shigemi 
Published: January 2025

AbstractThis study developed a consumption‐endogenous input–output analysis framework and a novel counterfactual structural decomposition analysis (SDA) framework to assess the economic, social, and environmental effects of the 2020 decline in foreign tourists due to the COVID‐19 pandemic. The results show a pandemic‐induced loss of 33 million tourists, resulting in 3.44 trillion JPY in value‐added losses, employment declines for 868,976 people, and environmental benefits of an 11.6 Mt‐CO2 emissions reduction. Sectors hit the hardest include hotels, eating and drinking services, and wholesale and retail trade. The deterioration revealed a 100% reduction in value added from foreign visitors, whereas shifts in production contributed to a 3.6% increase in CO2 emissions. This study recommends government intervention, focusing on stipends for sectors with the highest value‐added losses and employment declines, as well as support funds for sectors that reduce environmental impact.
Fiscal Policy Instruments for Inclusive Labor Markets: A Review
Authors: Ernst Ekkehard , Merola Rossana , Reljic Jelena 
Published: January 2025

ABSTRACTThis paper critically reviews fiscal policy instruments—including active labor market policies, social protection measures, care policies, and tax reforms—focusing on their differentiated impacts on underrepresented groups and their potential to foster labor market inclusivity. Our review reveals that empirical studies often overemphasize the capacity of individual policies to mitigate inequalities, neglecting the complex interdependencies among various mechanisms and policies. Instead, we argue for a systematic approach to ensure equitable access to good jobs and address disparities across labor market groups. Although sector‐specific training and reskilling are essential, their effects often take time to materialize, highlighting the necessity of complementary labor demand measures, such as public works schemes, and employment subsidies, to address immediate challenges and promote inclusive growth. Care policies remain central to improving female labor market participation by alleviating their unpaid care burdens. The review also identifies critical research gaps, including the need for longitudinal studies on long‐term policy impacts, an exploration of regional disparities in labor market inequalities, and sector‐specific effects of fiscal measures.
Cryptic diversity and evolutionary history of the fish species Xenotoca variata (Cyprinodontiformes: Goodeidae) in the Mexican Plateau: Implications for taxonomy and conservation
Authors: Beltrán‐López Rosa Gabriela , Domínguez‐Domínguez Omar , Pérez‐Ponce de León Gerardo , Mar‐Silva Adan Fernando , Perea Silvia , Pérez‐Rodríguez Rodolfo , Piller Kyle R. , Mejía‐Mojica Humberto , Doadrio Ignacio 
Published: January 2025

AbstractGeological and climatic events frequently represent the primary explanations to describe evolutionary processes among species. Freshwater fishes have been used previously as models to uncover evolutionary and historical biogeographic patterns in central Mexico, hydrologic systems and biotas. Xenotoca variata (Cyprinodontiformes: Goodeidae) is one of the most widely distributed species across central Mexico. The species represents a highly dimorphic and sexually selective species. In this study, the phylogenetic and phylogeographic patterns of populations of X. variata, using one mitochondrial locus (cytb) and three nuclear loci (S7, RHO, and RAG1), were described in order to understand the evolutionary history of the species throughout its distributional range. Two well‐defined and highly supported clades were recovered with all analyses and genes studied, with an estimated divergence time of ca. 2.42 Mya, corroborating the existence of an independent evolutionary unit in Cuitzeo Lake and its recognition as a putative new species. Also, a phylogeographic structure in two genes was found within the widely distributed clades. The role played by climate change events and geological history as well as the possible influence of reproductive traits in the phylogeographic pattern of the species are discussed.