bluuebunny/crossref_metadata_2025_split huggingface dataset:
Crystal Engineering Through Face Interactions Between Tetrahedral and Octahedral Building Blocks: Crystal Structure of [ε‐Al13O4(OH)24 (H2O)12]2 [V2W4O19] 3(OH)2×27H2O.
Authors: Son Jung‐Ho , Kwon Young‐Uk 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Novel 3‐D Heterobimetallic Cyano‐Bridged Coordination Polymer Incorporating Ag×××Ag Interaction: [Cu(dien)Ag(CN)2]2[Ag2(CN)3] [Ag(CN)2].
Authors: Zhou Hui‐Bo , Dong Wen , Liang Mao , Liao Dai‐Zheng , Jiang Zong‐Hui , Yan Shi‐Ping , Cheng Peng 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
The Crystal Structure of the Compound Ce3Ru4Al12 with Gd3Ru4Al12 Type
Authors: Bukhan'ko N. G. , Tursina A. I. , Malyshev S. V. , Gribanov A. V. , Seropegin Yu. D. , Bodak O. I. 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Pd/CaCO3 in Liquid Poly(ethylene glycol) (PEG): An Easy and Efficient Recycle System for Partial Reduction of Alkynes to cis‐Olefins under a Hydrogen Atmosphere.
Authors: Chandrasekhar S. , Narsihmulu Ch. , Chandrashekar G. , Shyamsunder T. 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Novel Route to Functionalized PFP Esters via Rapid Intermolecular Radical Addition to PFP Acrylate Mediated by Ethylpiperidinium Hypophosphite (EPHP).
Authors: Caddick Stephen , Hamza Daniel , Judd Duncan B. , Reich Melanie T. , Wadman Sjoerd N. , Wilden Jonathan D. 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Facile Preparation of β‐Fluoro Amines by the Reaction of Aziridines with Potassium Fluoride Dihydrate in the Presence of Bu4NHSO4.
Authors: Fan Ren‐Hua , Zhou Yong‐Gui , Zhang Wan‐Xuan , Hou Xue‐Long , Dai Li‐Xin 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Formation of P‐Ylide under Neutral and Metal‐Free Conditions: Transformation of Aziridines and Epoxides to Conjugated Dienes in the Presence of Phosphine.
Authors: Fan Ren‐Hua , Hou Xue‐Long , Dai Li‐Xin 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Free Radical‐Mediated Tandem Reaction of Dehydroamino Acid Derivative with π‐Allyl Palladium Complex: Synthesis of α,α‐Disubstituted Amino Acids.
Authors: Miyabe Hideto , Asada Ryuta , Yoshida Kazumasa , Takemoto Yoshiji 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Platinum(II)‐Catalyzed Reaction of 2‐Alkynylbenzoates or Benzothioates with Vinyl Ethers: A Concise Method for Synthesis of 1‐Acyl‐4‐alkoxy‐ or 1‐Acyl‐4‐alkylsulfanylnaphthalene Derivatives.
Authors: Kusama Hiroyuki , Funami Hideaki , Takaya Jun , Iwasawa Nobuharu 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Cu(acac)2 Immobilized in Ionic Liquids: A Novel and Recyclable Catalytic System for Aziridination of Olefins Using PhI=NTs as Nitrene Donor.
Authors: Kantam M. Lakshmi , Neeraja V. , Kavita B. , Haritha Y. 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Tin‐Complexation Strategy for Use with Diverse Acylation Methods in the Preparation of 1,9‐Diacyldipyrromethanes.
Authors: Tamaru Shun‐ichi , Yu Lianhe , Youngblood W. Justin , Muthukumaran Kannan , Taniguchi Masahiko , Lindsey Jonathan S. 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Potent Imidazole and Triazole CB1 Receptor Antagonists Related to SR141716.
Authors: Dyck Brian , Goodfellow Val S. , Phillips Teresa , Grey Jonathan , Haddach Mustapha , Rowbottom Martin , Naeve Gregory S. , Brown Brock , Sauders John 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New Biginelli Reaction Procedure Using Potassium Hydrogen Sulfate as the Promoter for an Efficient Synthesis of 3,4‐Dihydropyrimidin‐2(1H)‐one.
Authors: Tu Shujiang , Fang Fang , Zhu Songlei , Li Tuanjie , Zhang Xiaojing , Zhuang Qiya 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Biological Evaluation of Pyrrolo[2,1‐c][1,4]benzodiazepine (PBD) C8 Cyclic Amine Conjugates.
Authors: Masterson Luke A. , Croker Stephen J. , Jenkins Terence C. , Howard Philip W. , Thurston David E. 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Novel Functionalized Trisubstituted Allylboronates via Hosomi—Miyaura Borylation of Functionalized Allyl Acetates.
Authors: Ramachandran P. Veeraraghavan , Pratihar Debarshi , Biswas Debanjan , Srivastava Amit , Reddy M. Venkat Ram 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Fascicularones C and D, Tricyclo[5.4.0.02,5]undecane Sesquiterpenoids from the Liquid Culture of Naematoloma fasciculare.
Authors: Shiono Yoshihito , Wakamatsu Hiroko , Murayama Tetsuya , Ikeda Michimasa 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 4‐Amino‐5H‐2,3‐dihydroisothiazole‐1,1‐dioxide Ring Systems on Sugar Templates via Carbanion‐Mediated Sulfonamide Intramolecular Cyclization Reactions (CSIC Protocols) of Glyco‐α‐sulfonamidonitriles.
Authors: Dominguez Laura , Nguyen Van Nhien Albert , Tomassi Cyrille , Len Christophe , Postel Denis , Marco‐Contelles Jose 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Novel α‐Pyrones Produced by a Marine Pseudomonas sp. F92S91: Taxonomy and Biological Activities.
Authors: Singh Maya P. , Kong Fangming , Janso Jeffrey E. , Arias Daniel A. , Suarez Paola A. , Bernan Valerie S. , Petersen Peter J. , Weiss William J. , Carter Guy , Greenstein Michael 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
The Synthesis and Anticonvulsant Activity of Some ω‐Phthalimido‐N‐phenylacetamide and Propionamide Derivatives.
Authors: Soyer Zeynep , Kilic Fatma Sultan , Erol Kevser , Pabuccuoglu Varol 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Diastereoselective Synthesis and Configuration‐Dependent Activity of (3‐Substituted‐cycloalkyl)glycine Pyrrolidides and Thiazolidides as Dipeptidyl Peptidase IV Inhibitors.
Authors: Ashton Wallace T. , Dong Hong , Sisco Rosemary M. , Doss George A. , Leiting Barbara , Patel Reshma A. , Wu Joseph K. , Marsilio Frank , Thornberry Nancy A. , Weber Ann E. 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Copper and Silver Derivatives of Scorpionates and Related Ligands
Authors: Pettinari Claudio , Cingolani Augusto , Lobbia Giancarlo Gioia , Marchetti Fabio , Martini Domenico , Pellei Maura , Pettinari Riccardo , Santini Carlo 
Published: June 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Aberrant expression of CARM1, a transcriptional coactivator of androgen receptor, in the development of prostate carcinoma and androgen‐independent status
Authors: Hong Heng , Kao Chinghai , Jeng Meei‐Huey , Eble John N. , Koch Michael O. , Gardner Thomas A. , Zhang Shaobo , Li Lang , Pan Chong‐Xian , Hu Zhiqiang , MacLennan Gregory T. , Cheng Liang 
Published: May 2004

AbstractBACKGROUNDCoactivator‐associated arginine methyltransferase 1 (CARM1) is a transcriptional coactivator of the androgen receptor (AR). It is involved in the regulation of the biologic functions of the AR. It remains to be determined whether CARM1 is involved in prostatic carcinogenesis.METHODSThe expression of CARM1 in normal prostate epithelium, high‐grade prostatic intraepithelial neoplasia (PIN), and prostate carcinoma tissue was examined in 66 previously untreated patients with prostate carcinomas, as well as 12 patients with hormone‐independent prostate carcinoma, using immunohistochemical methods.RESULTSCell staining was observed in the cytoplasm and the nucleus. In 66 patients without previous hormonal treatment, the percentage of cells that stained positively for CARM1 in benign prostate tissue specimens (mean values: cytoplasm, 23%; nucleus, 16%) was statistically significantly less than the percentage of positively stained cells in PIN (mean values: cytoplasm, 56%; nucleus, 30%; P < 0.001) and in prostatic adenocarcinoma specimens (mean values: cytoplasm, 79%; nucleus, 53%; P < 0.001). The difference between adenocarcinoma and PIN also was statistically significant (P < 0.001). The staining intensity for CARM1 was significantly lower in benign prostate tissue specimens compared with PIN and prostatic adenocarcinoma specimens (P < 0.001). In the 12 patients with androgen‐independent prostatic adenocarcinoma, the expression of CARM1 was significantly increased when compared with patients without previous hormonal treatment. Expression of CARM1 was not correlated with age, Gleason score sum, pathologic stage, lymph node metastasis, extraprostatic extension, surgical margin status, vascular invasion, or perineural invasion.CONCLUSIONSThe authors found that overexpression of CARM1 was involved in the development of prostate carcinoma as well as androgen‐independent prostate carcinoma. Since CARM1 is functionally different from most other transcriptional coactivators of the AR, it may serve as a new target for the treatment of hormone‐independent prostate carcinoma. Cancer 2004. © 2004 American Cancer Society.
Circulating D‐dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma
Authors: Blackwell Kimberly , Hurẃitz Herbert , Liebérman Grazyna , Novotny William , Snyder Stacey , Dewhirst Mark , Greenberg Charles 
Published: May 2004

AbstractBACKGROUNDFibrin formation is required for tumor angiogenesis, metastasis, and invasion. D‐dimer, a fibrin degradation product, is produced when crosslinked fibrin is degraded by plasmin. The current study prospectively examined D‐dimer levels in patients with metastatic colorectal carcinoma treated in a Phase II randomized trial comparing bevacizumab (Avastin, Genentech, South San Francisco, CA) plus 5‐fluorouracil/leucovorin (5‐FU/LV) with 5‐FU/LV alone.METHODSAt least one circulating D‐dimer level was evaluable in 98 of the 104 previously untreated patients with metastatic colorectal carcinoma in the current trial. Plasma D‐dimer levels were determined using a quantitative immunoassay kit at enrollment, before each treatment, and at the time of trial completion or disease progression.RESULTSAt trial enrollment, 86 of 104 patients (88%) had elevated D‐dimer levels (> 20 ng/mL), and 86 of 102 patients (84%) had elevated carcinoembryonic antigen (CEA) levels (> 3 ng/mL). Baseline D‐dimer levels were correlated with the following baseline characteristics: CEA (Pearson coefficient, 0.31; P = 0.002), albumin levels (Pearson coefficient, −0.32; P = 0.002), tumor burden (Pearson coefficient, 0.30; P = 0.003), and number of metastatic sites (Pearson coefficient, 0.21; P = 0.04). At the time of progression, plasma D‐dimer levels reached a maximum postbaseline value in 51 of 61 patients (84%), whereas the CEA level was at its maximum postbaseline value in 39 of 55 patients (71%). Baseline D‐dimer levels were a strong predictor of overall survival on univariate analysis (P = 0.008) and multivariate analysis (P = 0.03). Overall, treatment with bevacizumab (5 mg/kg) and baseline D‐dimer levels were the only predictors of overall survival (P < 0.05).CONCLUSIONSThe current study indicates that fibrin remodeling is an important prognostic feature in metastatic colorectal carcinoma. D‐dimer levels should be incorporated into prognostic models, and D‐dimer may represent a useful biomarker for patients treated with antiangiogenic agents. Cancer 2004. © 2004 American Cancer Society.
Positron emission tomography for unexplained elevation of serum squamous cell carcinoma antigen levels during follow‐up for patients with cervical malignancies
Authors: Chang Ting‐Chang , Law Kim‐Seng , Hong Ji‐Hong , Lai Chyong‐Huey , Ng Koon‐Kwan , Hsueh Suei , See Lai‐Chu , Chang Yu‐Chen , Tsai Chien‐Sheng , Chou Hung‐Hsueh , Huang Kuan‐Gen , Liou Jui‐Der , Lin Cheng‐Tao , Chao Angel , Chen Min‐Yu , Wu Tzu‐I , Ma Shih‐Ya , Yen Tzu‐Chen 
Published: May 2004

AbstractBACKGROUNDDuring follow‐up for patients with cervical carcinoma, elevation of serum squamous cell carcinoma antigen (SCC‐Ag) levels in the absence of detectable recurrent lesions presents a diagnostic and therapeutic challenge. In the current prospective study, the authors evaluated the use of fluorine‐18‐labeled fluoro‐2‐deoxy‐D‐glucose (FDG) positron emission tomography (PET) to detect disease recurrence in this setting.METHODSWomen with cervical carcinoma who experienced complete responses to primary treatment or salvage therapy and who had no evidence of recurrent disease as detected by conventional methods but had serum SCC‐Ag levels ≥ 2.0 ng/mL on 2 consecutive occasions were eligible for the study. PET was performed within 2 weeks after the completion of conventional studies for the assessment of recurrence.RESULTSTwenty‐seven consecutive patients were registered for the current study. PET findings were positive for 19 patients: 14 who had a distant lesion or lesions, 2 who had a local lesion or lesions, and 3 who had both local and distant lesions. Of these 19 patients, 17 were confirmed to have recurrent disease; the remaining two were found to be free of disease but had severe anthracosis in the PET‐positive mediastinal lymph nodes. Seven of the eight patients with negative PET findings were not found to have recurrent disease on follow‐up. Overall, PET detected FDG‐avid lesions in 17 (94%; P < 0.001) of the 18 patients with recurrent disease. Seven of these 18 patients received therapy with curative intent; complete control was achieved in 6, four of whom currently are alive and free of disease. The addition of PET in the current setting curbed the use of futile curative therapy and significantly increased overall survival for patients in the current cohort compared with a historical group of 30 consecutive patients who had elevated SCC‐Ag levels as a first sign of recurrence.CONCLUSIONSPET expedited the detection of recurrent cervical carcinoma in patients with unexplained elevation of SCC‐Ag levels. Such expedited detection may have positive effects on patient survival. Cancer 2004. © 2004 American Cancer Society.
The utility of computed tomography scans in predicting suboptimal cytoreductive surgery in women with advanced ovarian carcinoma
Authors: Dowdy Sean C. , Mullany Sally A. , Brandt Kathy R. , Huppert Bonnie J. , Cliby William A. 
Published: June 2004

AbstractBACKGROUNDComputed tomography (CT) scans of the abdomen and pelvis may predict which patients with ovarian carcinoma can undergo optimal cytoreduction at primary surgery. Previous studies have demonstrated that patients with ovarian carcinoma had optimal cytoreduction rates ranging from 50–60%. The authors sought to determine whether these findings applied to a surgical practice with a higher rate of optimal debulking. A predictive model using CT scanning and CA 125 values would allow the authors to determine which patients would be more appropriately treated with neoadjuvant chemotherapy.METHODSPreoperative CT scans for patients with Stage III/IV ovarian carcinoma (according to the staging system of the International Federation of Gynecology and Obstetrics) who were treated between 1996 and 2001 were evaluated retrospectively by 2 radiologists for 17 criteria evaluating the extent of disease. Clinical data were extracted from medical records. Residual tumors measuring ≥ 1 cm were considered suboptimal. Logistic regression was used to evaluate which criteria correlated with optimal cytoreduction.RESULTSEighty‐seven patients were identified retrospectively who met entry criteria and had preoperative CT scans of sufficient diagnostic quality. Sixty‐two patients (71%) received optimal cytoreductive surgery and 45 (52%) required aggressive surgical procedures. In a multivariate model, only diffuse peritoneal thickening (DPT) independently predicted suboptimal surgical resection (P = 0.016). However, a model using both DPT and ascites on most CT scans had a positive predictive value of 68% and a sensitivity of 52% for predicting suboptimal cytoreduction.CONCLUSIONSThe presence of DPT and large‐volume ascites was associated with a very low rate of optimal cytoreduction (32%) in a surgical practice. These patients may be more appropriately treated with neoadjuvant chemotherapy followed by surgical cytoreduction. Cancer 2004. © 2004 American Cancer Society.
Divertor modelling of septum assessment experiments in JET MkIIGB
Authors: Tsitrone E. , Andrew P. , Bonnin X. , Coad P. , Coster D. , Fundamenski W. , Ghendrih P. , Huber A. , Jachmich S. , Kukushkin A. , Loarte A. , Matthews G. , Pitts R. , Rapp J. , Reiter D. , Stamp M. , Wischmeier M. , contributors to the JET EFDA work programme  
Published: June 2004

AbstractWe present results obtained from modeling the septum assessment experiments of the JET MkIIGB divertor with the B2‐Eirene code package. Similar L‐mode discharges have been performed with and without septum, varying density and gas puffing location. High and low inner wall clearance simulations are also compared, as this parameter has been shown experimentally to play an important role in the final density limit. According to the simulations, the neutrals ionization pattern is not affected by the septum, consistent with experiment. The septum does improve the pumped particle flux in the outer divertor, the inner divertor results depending on plasma‐wall clearance, but this only concerns a small fraction of the recycling flux at the targets (less than 2%) and does not influence the overall divertor plasma very much. Comparison between inner and outer gas fuelling with a moderate gas puff rate shows no difference in the simulations without septum, while a slight asymmetry is observed in the simulations with septum, showing that the septum allows acting separately on the inner and outer divertor. We conclude that a neutral flow exists linking outer and inner divertors with particles travelling around the plasma in the main chamber. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Mammary myofibroblastoma: Report of two cases with fine‐needle aspiration cytology and review of the cytology literature
Authors: Odashiro Alexandre N. , Odashiro Miiji Luciana N. , Odashiro Danilo N. , Nguyen Gia‐Khanh 
Published: May 2004

AbstractFine‐needle aspirates from two histologically, immunohistochemically, and ultrastructurally confirmed mammary myofibroblastomas (MM) of two elderly women revealed abundant, randomly arranged single and clustered benign spindle‐shaped mesenchymal cells with scant cytoplasm and elongated or oval nuclei displaying a finely granular chromatin pattern and inconspicuous nucleoli. In one case a few cells showed inconspicuous nuclear grooves. The aspirated tumor cells from the other case stained positively with desmin and CD34 antibodies and negatively with cytokeratin and S‐100 protein antibodies, in keeping with an MM. A review of the literature was briefly presented. Diagn. Cytopathol. 2004;30:406–410. © 2004 Wiley‐Liss, Inc.
Identification of cytomegalovirus in a liquid‐based gynecologic sample using morphology, immunohistochemistry, and DNA real‐time PCR detection
Authors: Sekhon Harmanjatinder S. , Press Richard D. , Schmidt Waldemar A. , Hawley Mary , Rader Anne 
Published: May 2004

AbstractThe viral cytopathic effects of cytomegalovirus (CMV) are rarely encountered in conventional cervical vaginal smears and have never been reported in a liquid‐based gynecologic sample (SurePath). We present results of a liquid‐based gynecologic sample (SurePath) from an asymptomatic patient with classic CMV‐associated granular or dense cyanophilic intracytoplasmic and intranuclear inclusion bodies with a clear surrounding zone. These inclusions were immunohistochemically positive for CMV. The patient also had human papilloma virus (HPV)‐associated koilocytes that showed a unique perinuclear immunostaining pattern suggesting coinfection with both CMV and HPV. CMV amplification using real‐time polymerase chain reaction (PCR) of DNA extracted from the liquid‐based sample confirmed the morphologic and immunohistochemical findings of CMV infection. These observations suggest that a liquid‐based preparation can be used to assess CMV infection morphologically, immunohistochemically, and by real‐time PCR. Diagn. Cytopathol. 2004;30:411–417. © 2004 Wiley‐Liss, Inc.
p27Kip1 Expression and grading of breast cancer diagnosed on cytological samples
Authors: Troncone Giancarlo , Migliaccio Ilenia , Caleo Alessia , Palmieri Emiliano A. , Iaccarino Antonino , Sparano Lucianna , Vetrani Antonio , Palombini Lucio 
Published: May 2004

AbstractThe progressive reduction in p27Kip1 (p27) protein immunohistochemical staining with increasing histological grading is a well‐established finding occurring in breast cancer, and its role as diagnostic complement and prognostic marker has been thoroughly evaluated. To clarify whether this test may be applied to breast cytopathology, we performed p27 immunostaining on fresh fine‐needle cytology (FNC) samples from 10 benign and 40 malignant breast lesions. On average, p27 immunostaining was significantly lower in carcinomas than in benign lesions (P < 0.005). In particular, among carcinomas, p27 immunostaining progressively reduced from well‐to poorly differentiated lesions (G1 vs. G2, P < 0.05; G1 vs. G3, P < 0.001; G2 vs. G3; P < 0.001). A similar trend was noted in a subgroup of 20 matched FNCs and histological samples of breast carcinomas, when p27 immunostaining on FNCs was stratified according to the histological grading (G1 vs. G2, P = 0.18; G1 vs. G3, P < 0.05; G2 vs. G3, P < 0.05). In addition, p27 immunostaining on FNCs showed a good positive correlation with that on histology (Spearman R = 0.58; P < 0.01), with a diagnostic concordance between samples of 85%, by using the standard 50% positive cell cutoff. Taken in concert, our data suggest that p27 immunostaining is a reliable marker of tumor cell differentiation in breast cytopathology as well as in histopathology. Accordingly, staining FNCs for p27 may be an useful complement in addition to cytological grading in the preoperative assessment of breast cancer. Diagn. Cytopathol. 2004;30:375–380. © 2004 Wiley‐Liss, Inc.
Papillary thyroid carcinoma with an adenoid cystic pattern: Report of a case with fine‐needle aspiration cytology and immunocytochemistry
Authors: Haji Bahiyah E. , Ahmed Mahmoud S. , Prasad Asha , Omar Moh'd S. , Das Dilip K. 
Published: May 2004

AbstractAlthough fine‐needle aspiration (FNA) cytologic features of conventional papillary thyroid carcinoma (PTC) and some of its variants have been documented in the literature, PTC with an adenoid cystic pattern has not so far been described. A 35‐year‐old woman presented with solitary cold nodule in the right lobe of thyroid. FNA smears from the nodule showed features of PTC such as papilliform clusters, monolayered sheets, psammoma bodies, increased frequency of nuclear grooves, and intranuclear cytoplasmic inclusions. In addition, there were areas of follicular formation and light‐pink to deep‐purple hyaline globules with a laminated appearance and surrounded by neoplastic cells, reminiscent of adenoid cystic carcinoma. These globules were present in 53% of the follicles. Immunocytochemical staining for thyroglobulin yielded positive cytoplasmic reaction in the neoplastic cells. Histopathology of the thyroidectomy specimen confirmed the cytodiagnosis of PTC. The hyaline globules were present focally and were light pink to deep purple with a laminated appearance resembling psamomma bodies. The colloid and follicular cells were positive for thyroglobulin but the hyaline globules were negative. Von Kossa staining for calcium revealed positive reaction in the psamomma bodies and some of the hyaline globules, indicating that the globules may be the beginning of psammoma bodies. Thus, FNA cytology was useful in diagnosing an unusual variant of PTC. Diagn. Cytopathol. 2004;30:418–421. © 2004 Wiley‐Liss, Inc.