bluuebunny/crossref_metadata_2025_split huggingface dataset:
Statistical Field Theory
Authors: Mussardo Giuseppe 
Published: November 2023

Abstract
This book provides a thorough introduction to the fascinating world of phase transitions as well as many related topics, including random walks, combinatorial problems, quantum field theory and S-matrix. Fundamental concepts of phase transitions, such as order parameters, spontaneous symmetry breaking, scaling transformations, conformal symmetry, and anomalous dimensions, have deeply changed the modern vision of many areas of physics, leading to remarkable developments in statistical mechanics, elementary particle theory, condensed matter physics and string theory. This self-contained book provides an excellent introduction to frontier topics of exactly solved models in statistical mechanics and quantum field theory, renormalization group, conformal models, quantum integrable systems, duality, elastic S-matrix, thermodynamics Bethe ansatz and form factor theory. The clear discussion of physical principles is accompanied by a detailed analysis of several branches of mathematics, distinguished for their elegance and beauty, such as infinite dimensional algebras, conformal mappings, integral equations or modular functions. Besides advanced research themes, the book also covers many basic topics in statistical mechanics, quantum field theory and theoretical physics. Each argument is discussed in great detail, paying attention to an overall coherent understanding of physical phenomena. Mathematical background is provided in supplements at the end of each chapter, when appropriate. The chapters are also followed by problems of different levels of difficulty. Advanced undergraduate and graduate students will find a rich and challenging source for improving their skills and for accomplishing a comprehensive learning of the many facets of the subject.
Space groups
Authors: Bradley C J , Cracknell A P 
Published: November 2023

Abstract
In section 1.5 we gave a descriptive account of the space groups and their labels and we introduced the Seitz notation for the symmetry operations that constitute the space group. In the present chapter we shall be concerned with the details of the identification of the 230 space groups, with the construction of reciprocal lattices and Brillouin zones and with an introduction to the problem of determining the irreducible representations of the space groups.
Remedies for Constitutional Violations
Authors: Yap Po Jen 
Published: November 2023

Abstract
Where courts in Asia are empowered to review the constitutionality of legislation, the standard practice is for the judiciary to invalidate the law, or relevant section of the law, if the court deems it unconstitutional. In common law systems, such invalidation traditionally operates immediately and retrospectively. Tradition also dictates that courts leave it to the legislature to introduce corrective legislation post-invalidation. This practice stems from judicial commitment to the separation of powers principle—a general rule observed in both civil and common law Asia. Courts in Asia are, however, breaking with tradition. They have now devised novel constitutional remedies that complement their invalidation power, usually in the absence of explicit constitutional or statutory authorization. This chapter examines four such constitutional remedies: (i) prospective invalidation, (ii) suspension order, (iii) remedial interpretation, and (iv) judicial directive.
Training police to de-escalate mental health crisis situations: Comparing virtual reality and live-action scenario-based approaches
Authors: Lavoie Jennifer , Álvarez Natalie , Baker Victoria , Kohl Jacqueline 
Published: November 2023

Abstract
Virtual reality is an emerging frontier that offers immersive simulations with the capacity to revolutionize police training. This study evaluated a scenario-based training approach by comparing the delivery of simulations in Virtual Reality (VR) and Live Action (LA). Participation in this mental health crisis response training program in either format led to a significantly greater acquisition of de-escalation competencies compared to a control group. VR format showed comparable effectiveness to the LA format in bringing about improved de-escalation skills through scenario-based training. The training was equally effective across all officer experience levels. The VR group showed a greater reduction in bias towards mental illness compared to the control group. Further, the VR format was found to be no more cognitively demanding than live action. The article discusses the centrality of de-escalation skills in police practice and considers the larger implications of de-escalation training delivered through virtual reality applications for increased consistency, cost-efficiencies, and professionalization.
Do Montreal! A Review Article
Authors: Ruhl J B 
Published: November 2023

Abstract
International climate change diplomacy has tried a rigid top-down approach (the Kyoto Agreement) and a more flexible bottom-up approach (the Paris Agreement). Neither approach has gained sufficient traction on the climate change problem. The authors of Fixing the Climate: Strategies for an Uncertain World propose a new direction. Borrowing from the framework of the Montreal Protocol of 1987, which made great strides in eliminating use of ozone-depleting chemicals, they outline a framework for “experimentalist governance” that relies on public and private organizations to promote a problem-solving approach that is, at the same time, both bottom-up and top-down, market based and institution based, technocratic and democratic. Using case studies and examples across a wide array of contexts—from U.S. coal-fired power-plant sulfur dioxide emissions to dairy farm pollution in Ireland—they build the case for infusing climate change governance with innovation-driven institutions, processes, and instruments. The case studies and examples, however, share several common features that suggest experimentalist governance thrives under ideal conditions, including clearly defined technology challenges and ability to contain the impacts of innovation largely to the incumbent industry. Under the Montreal Protocol, for example, switching chemicals in products did not require consumers to change behavior or make substantial sacrifices. Many of the challenges of climate change policy fit these and the other ideal conditions, but many do not. The full extent of the necessary energy transition, as well as the demands of climate change adaptation, present complex socioeconomic policy issues fraught with political division. Experimentalist governance can go a long way toward fixing the climate, but ultimately, fixing the climate also will require fixing the climate politics.
NIR-switchable local hydrogen generation by tandem bimetallic MOFs nanocomposites for enhanced chemodynamic therapy
Authors: Zhong Jun , Zheng Xiang , Wen Yuan , Li Yuewei , Zhang Jianting , Kankala Ranjith Kumar , Wang Shibin , Chen Aizheng 
Published: November 2023

Abstract
The inadequate quantity of hydrogen peroxide (H2O2) in cancer cells promptly results in the constrained success of chemodynamic therapy (CDT). Significant efforts made throughout the years; nevertheless, researchers are still facing the great challenge of designing a CDT agent and securing H2O2 supply within the tumor cell. In this study, taking advantage of H2O2 level maintenance mechanism in cancer cells, a nanozyme-based bimetallic metal-organic frameworks (MOFs) tandem reactor is fabricated to elevate intracellular H2O2 levels, thereby enhancing CDT. In addition, under near-infrared excitation, the upconversion nanoparticles (UCNPs) loaded into the MOFs can perform photocatalysis and generate hydrogen, which increases cellular susceptibility to radicals induced from H2O2, inhibits cancer cell energy, causes DNA damages and induces tumor cell apoptosis, thus improving CDT therapeutic efficacy synergistically. The proposed nanozyme-based bimetallic MOFs-mediated CDT and UCNPs-mediated hydrogen therapy act as combined therapy with high efficacy and low toxicity.
A two-process model of Drosophila sleep reveals an inter-dependence between circadian clock speed and the rate of sleep pressure decay
Authors: Abhilash Lakshman , Shafer Orie Thomas 
Published: November 2023

Abstract
Sleep is controlled by two processes—a circadian clock that regulates its timing and a homeostat that regulates the drive to sleep. Drosophila has been an insightful model for understanding both processes. For four decades, Borbély and Daan’s two-process model has provided a powerful framework for understanding sleep regulation. However, the field of fly sleep has not employed such a model as a framework for the investigation of sleep. To this end, we have adapted the two-process model to the fly and established its utility by showing that it can provide empirically testable predictions regarding the circadian and homeostatic control of fly sleep. We show that the ultradian rhythms previously reported for loss-of-function clock mutants in the fly are robustly detectable and a predictable consequence of a functional sleep homeostat in the absence of a functioning circadian system. We find that a model in which the circadian clock speed and homeostatic rates act without influencing each other provides imprecise predictions regarding how clock speed influences the strength of sleep rhythms and the amount of daily sleep. We also find that quantitatively good fits between empirical values and model predictions were achieved only when clock speeds were positively correlated with rates of decay of sleep pressure. Our results indicate that longer sleep bouts better reflect the homeostatic process than the current definition of sleep as any inactivity lasting 5 minutes or more. This two-process model represents a powerful framework for work on the molecular and physiological regulation of fly sleep.
The organization of sleep–wake patterns around daily schedules in college students
Authors: Lu Sinh , Stone Julia E , Klerman Elizabeth B , McHill Andrew W , Barger Laura K , Robbins Rebecca , Fischer Dorothee , Sano Akane , Czeisler Charles A , Rajaratnam Shantha M W , Phillips Andrew J K 
Published: November 2023

Abstract
The amount of time available in a day is fixed, and consequently, sleep is often sacrificed for waking activities. For college students, daily activities, comprised of scheduled classes, work, study, social, and other extracurricular events, are major contributors to insufficient and poor-quality sleep. We investigated the impact of daily schedules on sleep–wake timing in 223 undergraduate students (age: 18–27 years, 37% females) from a United States university, who were monitored for ~30 days. Sleep–wake timing and daily recorded activities (attendance at academic, studying, exercise-based, and/or extracurricular activities) were captured by a twice-daily internet-based diary. Wrist-worn actigraphy was conducted to confirm sleep–wake timing. Linear mixed models were used to quantify associations between daily schedule and sleep–wake timing at between-person and within-person levels. Later scheduled start time predicted later sleep onset (between and within: p &lt; .001), longer sleep duration on the previous night (within: p &lt; .001), and later wake time (between and within: p &lt; .001). Later schedule end time predicted later sleep onset (within: p &lt; .001) and shorter sleep duration that night (within: p &lt; .001). For every 1 hour that activities extended beyond 10 pm, sleep onset was delayed by 15 minutes at the within-person level and 40 minutes at the between-person level, and sleep duration was shortened by 6 and 23 minutes, respectively. Increased daily documented total activity time predicted earlier wake (between and within: p &lt; .001), later sleep onset that night (within: p &lt; .05), and shorter sleep duration (within: p &lt; .001). These results indicate that daily schedules are an important factor in sleep timing and duration in college students.
Clinical Trial: Multi-scale Modeling of Sleep Behaviors in Social Networks; URL: https://clinicaltrials.gov/study/NCT02846077; Registration:NCT02846077.
U.S. Attending Anesthesiologist Burnout in the Postpandemic Era
Authors: Afonso Anoushka M. , Cadwell Joshua B. , Staffa Steven J. , Sinskey Jina L. , Vinson Amy E. 
Published: November 2023

Background
Anesthesiologists are experiencing unprecedented levels of workplace stress and staffing shortages. This analysis aims to assess how U.S. attending anesthesiologist burnout changed since the onset of the COVID-19 pandemic and target well-being efforts.

Methods
The authors surveyed the American Society of Anesthesiologists’ U.S. attending anesthesiologist members in November 2022. Burnout was assessed using the Maslach Burnout Inventory Human Services Survey with additional questions relating to workplace and demographic factors. Burnout was categorized as high risk for burnout (exhibiting emotional exhaustion and/or depersonalization) or burnout syndrome (demonstrating all three burnout dimensions concurrently). The association of burnout with U.S. attending anesthesiologist retention plans was analyzed, and associated factors were identified.

Results
Of 24,680 individuals contacted, 2,698 (10.9%) completed the survey, with 67.7% (1,827 of 2,698) at high risk for burnout and 18.9% (510 of 2,698) with burnout syndrome. Most (78.4%, n = 2,115) respondents have experienced recent staffing shortages, and many (36.0%, n = 970) were likely to leave their job within the next 2 yr. Those likely to leave their job in the next 2 yr had higher prevalence of high risk for burnout (78.5% [760 of 970] vs. 55.7% [651 of 1,169], P < 0.001) and burnout syndrome (24.3% [236 of 970] vs. 13.3% [156 of 1,169], P < 0.001) compared to those unlikely to leave. On multivariable analysis, perceived lack of support at work (odds ratio, 9.2; 95% CI, 7.0 to 12.1), and staffing shortages (odds ratio, 1.96; 95% CI, 1.57 to 2.43) were most strongly associated with high risk for burnout. Perceived lack of support at work (odds ratio, 6.3; 95% CI, 3.81 to 10.4) was the factor most strongly associated with burnout syndrome.

Conclusions
Burnout is more prevalent in anesthesiology since early 2020, with workplace factors of perceived support and staffing being the predominant associated variables. Interventions focused on the drivers of burnout are needed to improve well-being among U.S. attending anesthesiologists.

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Predicting hepatic encephalopathy in patients with cirrhosis: A UK population–based study and validation of risk scores
Authors: Jones Bethan I. , Jenkins Cerys A. , Murphy Daniel , Orr James , Yeoman Andrew , Hubbuck Ellen R. , Heywood Ben R. , Currie Craig J. 
Published: November 2023

Background:
HE is a common neurologic complication in cirrhosis associated with substantial disease and economic burden. HE symptoms are nonspecific and there are limited ways of identifying patients with cirrhosis at high risk of later developing HE. A risk score was previously developed to identify patients at risk of developing HE in a predominately male US cohort. Here, we evaluated the performance of the HE risk scores in a UK cohort study.

Methods:
Health care records from Clinical Practice Research Datalink and linked Hospital Episode Statistics were used to select patients with cirrhosis who were diagnosed with HE, confirmed by a diagnosis code for HE or a rifaximin-α prescription. The index date was the date of incident cirrhosis. The study period was from January 2003 to June 2019.

Results:
A total of 40,809 patients with cirrhosis were selected in the UK cohort, of whom 59% were male. A total of 1561 patients were diagnosed with HE. Applying the UK cohort to the baseline sensitivity risk cutoff (≥−11) from the US cohort provided a sensitivity of 92% and a negative predictive value of 99%. Within a longitudinal model, applying a sensitivity cutoff of ≥−3 to this cohort gave a sensitivity of 89% and a negative predictive value of 99%.

Conclusions:
Using data from the UK, the previously developed HE risk scores were found to be reliable for selecting those most likely to progress to HE in patients with liver cirrhosis. Despite the HE risk scores originally being estimated using the data from a predominately male US cohort, the scores were validated and found to be generalizable to female patients.
Anesthetic considerations in interventional pulmonology
Authors: Sikachi Rutuja R. , Mishra Kelly Louise , Anders Megan 
Published: November 2023

Purpose of review
In this review, we highlight the important anesthetic consideration that relate to interventional bronchoscopic procedures for the management of central airway obstruction due to anterior mediastinal masses, endoluminal endobronchial obstruction, peripheral bronchoscopy for diagnosis and treatment of lung nodules, bronchoscopic lung volume reduction and medical pleuroscopy for diagnosis and management of pleural diseases.

Recent findings
The advent of the field of Interventional Pulmonology has allowed for minimally invasive options for patients with a wide range of lung diseases which at times have replaced more invasive surgical procedures. Ongoing research has shed light on advancement in anesthetic techniques and management strategies that have increased the safety during peri-operative management during these complex procedures. Current evidence focusing on the anesthetic techniques is presented here.

Summary
The field of Interventional Pulmonology requires a tailored anesthetic approach. Recent advancements and ongoing research have focused on expanding the partnership between the anesthesiologist and interventional pulmonologists which has led to improved outcomes for patients undergoing these procedures.
Laparoscopic transabdominal preperitoneal (TAPP) groin hernia repair using n-butyl-2-cyanoacrylate (LiquiBandFIX8) for mesh fixation and peritoneal closure: case report about extraperitoneal hematoma
Authors: Raab Sandra , Huber Livia , Fortelny René , Shamiyeh Andreas 
Published: November 2023

Introduction:
A symptomatic inguinal hernia is a prevalent condition that typically requires surgical intervention. Various surgical approaches have been established for hernia repair, including several techniques for peritoneal closure and mesh fixation in laparoscopic surgery. N-butyl-2-cyanoacrylate, such as LiquiBandFIX8, offers a time-saving alternative to invasive methods for both mesh fixation and peritoneal closure. While n-butyl-2-cyanoacrylate is employed in various closure procedures, LiquiBandFIX8 is specifically designed for mesh fixation in inguinal hernia repair.

Case presentation:
We present a case of a 68-year old man undergoing transabdominal preperitoneal inguinal hernia repair under full heparinization. LiquiBandFIX8 was employed for mesh fixation and peritoneal closure. Upon conducting a revision laparoscopy due to a significant postoperative hematoma, we found that the mesh and peritoneum remained undamaged and fully sealed, indicating an effective fixing technique. Both the initial repair and the subsequent revision surgery were documented and the videos were subsequently analyzed.

Conclusion:
LiquiBandFIX8 provides a reliable adhesive strength and appropriate application for peritoneal closure and mesh fixation. When encountering extraperitoneal fluid collection, there is no anticipation of intraabdominal complications.
Double aneuploidy in a 2-month-old male with Edward syndrome and Klinefelter syndrome: a case report
Authors: Mansour Marah , AlZoubi Ahmed , Zoukar Sham , Aljammal Ghina , Makki Raghad , Khaled Noor Al Huda , Aletesh Yara , Aljundi Rama , Mohammad Deeb Ahmad , Ajlouni Mohammad Obada 
Published: November 2023

Introduction and importance:
Edward syndrome is a severe chromosomal defect that occurs as a result of non-disjunction through meiosis. It presents with cardiac septal defects, horseshoe kidneys, patent ductus arteriosus, central nervous system dysgenesis, distinctive craniofacial deformities, and overriding or overlapping fingers. Klinefelter syndrome (47, XXY) is found in 1 in 660 newborn males. It is considered to be one of the most common genetic causes of infertility. It manifests with small firm testes, androgen insufficiency, and azoospermia.

Case presentation:
A 2-month-old male infant with a history of weakness in feeding, frequent convulsions, and an increase in cyanosis two days ago. There were multiple skeletal deformities and a tendency to spasm in the extremities, left ventricular atrophy, mitral atresia, atrial septal defect, ventricular septal defect with dilated right cavities, tricuspid valve regurgitation, pulmonary valve stenosis; and the aorta exits in the right ventricle. There is a widening of the subdural space, which was observed in the left frontal-parietal side with cortical atrophy in that area and a widening of the Sylvian fissure. A karyotype test confirmed the presence of Edward and Klinefelter syndromes.

Clinical discussion:
Aneuploidy is a chromosomal issue characterized by an abnormal number of a chromosome copies. The coexistence of two aneuploidies is called “double aneuploidy” which is a rare occurrence. Herein, we report a case of a 2-month-old male with Edward syndrome and Klinefelter syndrome.

Conclusion:
This publication aims to highlight the challenges in diagnosing and treating a complicated genetic disease.
MDR/XDR/PDR or DTR? Which definition best fits the resistance profile of Pseudomonas aeruginosa?
Authors: Cosentino Federica , Viale Pierluigi , Giannella Maddalena 
Published: November 2023

Purpose of review
The aim of this narrative review is to compare the prognostic utility of the new definition of difficult-to-treat resistance (DTR) vs. established definitions in patients with Pseudomonas aeruginosa infection to understand the therapeutic implications of resistance classification and its impact on clinical outcome.

Recent findings
Among Gram-negative bacteria (GNB), P. aeruginosa (PA) is associated with high rates of morbidity and mortality, mostly related to its intrinsic capacity of developing antibiotic resistance. Several classifications of antibiotic resistance have been proposed in the last 15 years. The most common used is that from Magiorakos et al. including multidrug resistance (MDR), extensively drug-resistant (XDR) and pan drug resistance (PDR) according to the number of antibiotic classes showing in vitro activity. A further classification based on the resistance to specific antibiotic classes (i.e. fluoroquinolones, cephalosporins, carbapenem resistance) was also proposed. However, both of them have been criticized because of limited usefulness in clinical practice and for poor correlation with patient outcome, mainly in infections due to PA. More recently the new definition of difficult-to-treat resistance (DTR) has been proposed referring to nonsusceptibility to all first-line agents showing high-efficacy and low-toxicity (i.e. carbapenems, β-lactam-β-lactamase inhibitor combinations, and fluoroquinolones). Studies including large cohorts of patients with GNB bloodstream infections have confirmed the prognostic value of DTR classification and its clinical usefulness mainly in infections due to PA. Indeed, in the recent documents from the Infectious Diseases Society of America (IDSA) on the management of antibiotic resistant GNB infections, the DTR classification was applied to PA.

Summary
DTR definition seems to identify better than MDR/XDR/PDR and single class resistant categories the cases of PA with limited treatment options. It requires periodic revision in order to remain up-to-date with the introduction of new antibiotics and the evolving pattern of resistance.