bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arusuvai and the taste receptor pharmacology in relation to clinical Siddha medicine
Authors: Veeraputhiran Balasubramaniyan , Arumugam Swaminathan , Venkatachalam Balamurugan 
Published: January 2025

Abstract

Background:
Taste is a chemoreception process and constitutes one of the five special senses in humans, and our reliance on taste for food consumption and habits can change over time. On a molecular level, the taste sensation is the process of chemoreception. This review aims to summarize and discuss the current knowledge of taste receptor pharmacology in relation to clinical Siddha medicine. Identification and confirmation of taste are purely initiated by interactions between tastants found in food and receptors located in taste buds. Even single-celled organisms possess sweet and salt receptors on their membranes. After crossing the tongue, the taste organ, chemoreceptive activity travels from the brain to the dermis. Although primitive times lacked concepts or theories of molecular identification, people relied solely on taste to understand the common content and effects of substances. This same concept was applied to the practice of medicine. Before understanding the specific medicinal effects of plants, ancient medical practitioners employed existing taste concepts for treating illnesses.

Conclusion:
According to the traditional Tamil medicine concept, in addition to four basic tastes accepted by modern science such as sweet, sour, salt, and bitter, pungent and astringent are also mentioned as primary taste sensations.
Management of Mulai Mookadaipu (nasal polyp) with Manjal Kara applications: A case study
Authors: Ganesan Sabaratnam , Sritharan Anpuchelvy , Sritharan Ganesh 
Published: January 2025

Abstract
The Siddha system of medicine, one of the oldest and most spiritually rooted healing traditions, integrates external therapies and internal medicines for managing health and disease. Nasal polyps, which commonly affect young and older adults, are closely associated with Mulai Mookadaipu in Siddha medicine. This condition is characterized by the abnormal growth of Oon (muscle) and kozhuppu (fatty tissue) within the nasal passages. This case study focuses on a 50-year-old female patient who presented with symptoms of nasal blockage, difficulties in breathing, and anosmia. Clinical examination revealed left maxillary sinus tenderness and nasal polyps in the left nostril, confirmed by a computerized tomography scan. The patient, who had a history of nasal blockage, had previously undergone allopathic treatment but declined the recommended surgical intervention, Instead, she opted for Siddha medicine, where her condition was treated as a chronic nasal polyp using a combination of nasal applications (Nasiyam and Karam Therapy) and internal medicines. The holistic Siddha treatment approach effectively managed the patient’s symptoms, leading to significant improvement in nasal blockage and breathing.
Educational Series: Hydroxyurea Use in Children with Sickle Cell Disease, Congestive Cardiac Failure in Children, Management of Coma in Children and Oesophageal Atresia
Authors: Adegoke Samuel A , Anah Maxwell U , Sadoh Wilson E , Ahmad Murtala M , Anarado Chika , Ayuk Adaeze C 
Published: January 2025

Sickle Cell Disease (SCD) is a global health problem, although about 90% of the burden occurs in Low-and Middle-Income Countries (LMICs). Globally, about 300,000 babies are born with the disease annually, with about 150,000 of them in Nigeria alone. The Nigeria 2018 Demographic Health Survey estimated the average birth prevalence of homozygous sickle cell disease (HbSS) as 1·21% and 0·24% for the heterozygous state HbSC.1,2 SCD is a single gene mutation characterized by GAG to GTG transversion resulting in the replacement of soluble glutamic acid by insoluble valine at the sixth position of the β-globin chain (β6 Glu →Val, GAG>GTG).3 Clinically, it typically manifests as episodic ischaemia and hypoxia, resulting in recurrent pains (the disease hallmark), chronic haemolysis and increased predisposition to infections.
Vol. 6, N.º 1, Jan-Jun 2025 - "Promoção e Divulgação da Radiologia"
Authors: Editorial Conselho 
Published: January 2025

Décima publicação da ROENTGEN - Revista Científica das Técnicas Radiológicas, com especial destaque para a temática "Promoção e Divulgação da Radiologia".
Este número da ROENTGEN visa promover e divulgar a Radiologia e reconhecer e valorizar o papel dos vários profissionais de saúde desta área, incluindo os Técnicos de Radiologia, enquanto verdadeiros protagonistas da imagem em saúde.
A Comparative Study On The Effectiveness Of Mouthwash Using Intelligent System and Its Effect to COVID-19
Authors: Gelisen Mehmet Ilker , Ozsahin Dilber Uzun , Agachan Yasemin , Duwa Basil , Gumusoglu Miray , Onkol Ozgun , Uzun Berna 
Published: January 2025

While COVID-19 is no longer the main public health challenge, we should still exercise caution. The rapid spread of the virus in the past presented a significant threat to public health, highlighting the need for continued vigilance and effective preventive measures. Over the years, science-related groups, institutions, healthcare services, schools and companies have collaborated in finding a common remedy to contain the virus. Therefore, there is a need of using safer products to disinfect or prevent the presence of the virus in our environs.
Hemispheric asymmetry in recent stratospheric age of air changes
Authors: Dubé Kimberlee , Tegtmeier Susann , Ploeger Felix , Walker Kaley A. 
Published: January 2025

Abstract. Many stratospheric trace gases, including O3, HCl, and NOy, have had opposing trends in the Southern Hemisphere (SH) compared to the Northern Hemisphere (NH) during the last 2 decades. Some of this difference is due to hemispherically asymmetric changes in the rate of transport by the Brewer–Dobson circulation (BDC), and some is due to ozone depletion and recovery. The mean age of air (AoA) is a common proxy for the transport rate by the BDC in models; however it cannot be directly measured. We use observations from the Atmospheric Chemistry Experiment Fourier transform spectrometer (ACE-FTS) along with results from the Chemical Lagrangian Model of the Stratosphere (CLaMS) to derive AoA anomalies and AoA trends. The AoA is derived using observations of N2O, CH4, and CFC-12, all long-lived trace gases with tropospheric sources. We also consider CLaMS simulations driven with four different reanalyses (ERA5, ERA-Interim, JRA-55, MERRA-2). We find that, irrespective of which trace gas or reanalysis is used, air in the NH aged by up to 0.3 years per decade relative to the SH over 2004–2017. The maximum hemispheric difference in aging occurs in the middle stratosphere, near 30 hPa (∼ 24 km). We also show that the aging rate in the NH becomes smaller when the analysis is extended to 2021. The observed aging in the NH middle stratosphere contradicts model predictions of a decrease in stratospheric AoA in response to rising atmospheric greenhouse gas levels. However, the smaller aging rate during 2004–2021 compared to 2004–2017 provides some evidence that the NH aging is impacted by decadal variability and the limited length of the observation period.
IMPLEMENTASI PEMBELAJARAN PKN DALAM MENANAMKAN NILAI-NILAI KARAKTER BERBASIS KEARIFAN LOKAL BUDAYA BIMA
Authors: Wahyuningsih Nurul , Mahmudah Husnatul , Kusumawati Yayuk , Maulana Ikhsan 
Published: January 2025

Pendidikan Pancasila merupakan aspek penting dalam pembentukan karakter dan nilai-nilai yang kuat dalam diri individu. Salah satu pendekatan yang efektif dalam mengintegrasikan nilai-nilai karakter ke dalam pembelajaran Pancasila adalah dengan memanfaatkan kearifan lokal budaya. Sebagai kearifan lokal yang kaya, budaya Bima memiliki nilai-nilai yang relevan dan dapat menjadi sumber inspirasi untuk pembentukan karakter. Penelitian ini bertujuan untuk menjelaskan implementasi pembelajaran Pendidikan Pancasila dengan memanfaatkan kearifan lokal budaya Bima dalam menanamkan nilai-nilai karakter. Pendekatan yang digunakan dalam penelitian ini adalah studi literatur dan analisis konten. Berdasarkan penelitian ini, ditemukan bahwa pendekatan yang mengintegrasikan pembelajaran Pancasila dengan kearifan lokal budaya Bima dapat secara efektif meningkatkan pemahaman dan penerapan nilai-nilai karakter pada siswa. Hasil penelitian menunjukkan bahwa implementasi pembelajaran Pendidikan Pancasila dengan pendekatan kearifan lokal budaya Bima memungkinkan siswa untuk menginternalisasi nilai-nilai seperti gotong royong, kejujuran, tanggung jawab, rasa menghargai, dan toleransi. Melalui kegiatan pembelajaran, pembiasaan-pembasaan dan nilai-nilai yang karakter yang terdapat pada budaya Bima, siswa dapat memahami dan mengaplikasikan nilai-nilai tersebut dalam kehidupan sehari-hari.
Identification of Actionable Insights from Online Data Sources by using the Hashed Coherence Frequency Calculator (HCFC) Algorithm
Authors: B. Srinivasan  
Published: January 2025

The present contemporary world is propelled by data. Everyone in society makes decisions based on the existing data and proceeds accordingly. Furthermore, all machinery is automated using advanced technologies such as Artificial Intelligence (AI), Internet of Things (IoT), Machine Learning (ML), and Data Science (DL), which predominantly harness data-driven insights for daily operations. Business organizations, social media, healthcare, big data analytics, and locality mapping are just a few modern industries that rely heavily on data-driven strategies. These areas utilize Cloud Computing (CC) to store the data in the cloud and allow access to data on any device. The primary consideration in data-driven terminology is that not all available data is utilized for decision-making. Hence, before adopting a data-driven process, it is essential to identify a collection of trustworthy and actionable insights that will enable better decision-making. This paper proposes a novel algorithm, the Hashed Coherence Frequency Calculator (HCF), for segregating actionable and non-actionable insights from the given dataset and enabling better decision-making. The algorithm is applied over two case studies containing Amazon product reviews and Google Play Store Apps review datasets. The coherent frequency count statistical measure is mainly applied to identify actionable insights, and the outcomes will also be compared with the existing approaches.
Reversed Degree-Based Topological Indices of Alkane Line Graphs
Authors: Divya L  
Published: January 2025

This paper investigates the topological indices based on reversed degree of the alkane line graph. The least reactive and most basic hydrocarbons found in organic compounds are alkanes, which are made up only of carbon and hydrogen atoms and lack any additional functional groups. In this work, the topological indices listed below were computed, specifically, the Reverse Randic index , Reverse atom bond connectivity index , Reverse geometric arithmetic index , Reverse first and Reverse second Zagreb indices , Reverse first and Reverse second Zagreb co-indices ,Reverse hyper Zagreb index , Reverse forgotten index , Reverse Balaban index ,Reverse first multiplicative-Zagreb indices , Reverse second multiplicative-Zagreb index and Reverse redefined first, second, and third Zagreb indices for the alkane line graph . The comparison of the topological indices has also been shown graphically. The results show that the Zagreb index with reverse first multiple has the highest value. It is demonstrated that the reverse first multiple Zagreb index has the best prediction performance among all the computed molecular descriptors. Additionally, a numerical and graphical comparison of these topological indices is included in this investigation.
Factores de riesgo asociados al síndrome de burnout en docentes de la provincia del Carchi
Authors: Velasco-Benavides Juan , Herrera Erick 
Published: January 2025

Resumen. El síndrome de burnout es ampliamente conocido como un motivo de problema laboral que aqueja al personal docente a nivel mundial. Este problema relacionado con factores de riesgo que generan estrés surge debido al entorno laboral y diversas situaciones ligadas al trato con personas que demandan un alto nivel de dedicación e involucramiento. El presente estudio se centró en identificar factores de riesgo asociados al síndrome de burnout en docentes de la provincia del Carchi. El objetivo principal fue validar la adaptación del Inventario de Burnout de Maslach (MBI) al contexto educativo específico, y proponer un modelo de análisis de resultados basado en inteligencia artificial. Al validar el instrumento se identificó que este no se adaptaba completamente al contexto local por lo que el instrumento fue modificando, teniendo que removerse 5 preguntas que fueron identificadas como no relevantes mediante el Análisis Factorial Confirmatorio, y se incorporó información demográfica de los participantes considerada de interés para las instituciones participantes. De esta manera, para la extracción de resultados a partir del test, se diseñó un nuevo modelo de procesamiento de resultados basado en técnicas multivariantes, contemplando 37 variables de entrada. Para esto se consideraron múltiples alternativas, incluidos clasificadores binarios, redes neuronales poco profundas y cinco modelos de aprendizaje profundo, encontrando que el aprendizaje profundo, especialmente un modelo de cinco capas desarrollado con TensorFlow y Keras, ofrecía las predicciones más precisas sobre el agotamiento emocional, una dimensión clave del síndrome de burnout. Este modelo alcanzó una precisión del 86% y un MSE de 0.1193604, demostrando su fiabilidad para la detección automática del síndrome sin necesidad de diagnóstico profesional. La investigación valida la adaptación del instrumento al contexto objetivo y resalta la importancia de establecer nuevos modelos de análisis cuando se emplean instrumentos modificados a partir del MBI, asegurando su relevancia y aplicabilidad en contextos específicos.

Palabras Clave: Síndrome de Burnout, Factores de Riesgo, Red Neuronal Artificial
Margaritasita: Un mineral exclusivamente Chihuahuense
Authors: Faudoa Gómez Fabián Guadalupe , Montero Cabrera María Elena , Esparza Ponce Hilda Esperanza , Fuentes Cobas Luis Edmundo , Canche Tello Jesús Gonzalo 
Published: January 2025

La margaritasita [Cs2(UO2)2(VO4)2·nH2O] es un uranovanadato descrito hasta el día de hoy únicamente en la Sierra Peña Blanca, Chihuahua. En este trabajo se comparten los resultados obtenidos de la caracterización de margaritasita, empleando las técnicas de difracción de rayos X de alta resolución (DRX-AR) y espectroscopía de estructura fina por la absorción de rayos X (EXAFS), las cuales utilizan luz sincrotrón. Para este trabajo se realizó la caracterización en el sincrotrón de Diamond Light Source estación B18 (en Reino Unido) y en el difractómetro de alta precisión de Elettra en Triestre (Italia).
La margaritasita, con hábito tabular micrométrico entre 1 y 3 μm, presenta las fases margaritasita pura y carnotita en solución sólida desordenada con una relación de potasio (K) y cesio (Cs) de 1:1, acompañadas de cuarzo, montmorillonita, feldespato potásico y calcita. Mediante estructura de los rayos X cerca del borde de absorción (por sus siglas en inglés XANES) y EXAFS se comprobó la asociación de vanadio y cesio con uranio en la fase margaritasita. En el estudio se caracterizó la estructura del prisma pentagonal uranilo determinando las distancias de unión entre el uranio y el oxígeno U-O, característica de los uranovanadatos.
DOI: https://doi.org/10.54167/tch.v19i1.1675
PELATIHAN PENANAMAN TANAMAN OBAT KELUARGA (TOGA) UNTUK MENINGKATKAN PENGETAHUAN MASYARAKAT DESA PLAOSAN SIDOARJO
Authors: Wahyu Budi Pratama Muhamad Dion , Claresta Nathania Resty , Hakim Luqmanul , Khusna Asmaul , Yeyen Tua Mariana Anjali , Arditiya Rheyna Putri , Nasrullah Rachmad , Alfarisi Muhammad Salman , Safitri Avida Nurisa , Prajitno Sunyoto Hadi 
Published: January 2025

Abstract: The program implemented by KKN students Family medicinal plants (TOGA) are being planted and used in an attempt to enhance family health, particularly in the food industry. program. In this program students use methods including (1) preparation, preparing what will be done and what items will be used. (2) debriefing, providing debriefing through socialization at one of the RW village halls. And (3) implementing the KKN program, planting each RW with 10 TOGA plant seeds consisting of three tomato seeds, three eggplant seeds and 4 chili seeds. The benefits and properties of TOGA that are cultivated are not yet known, therefore outreach is needed to the local community to better understand and know the benefits of the TOGA plant for our body's health, although the benefits of TOGA have been known for a long time, its use is limited to a concoction that has been prepared as a family medicine for many years. But few individuals are aware of the advantages. of the TOGA plant, therefore this outreach can help people become more familiar with the TOGA plant and its benefits for the body to maintain health. Keywords: Plants; TOGA; Plaosan Village Abstrak: Inisiatif penanaman dan konsumsi Tanaman Obat Keluarga (TOGA) mahasiswa KKN bertujuan untuk meningkatkan kesehatan keluarga, khususnya di sektor pangan. Dalam program ini mahasiswa menggunakan metode yang dilakukan antara lain (1) persiapan, mempersiapkan apasaja yang akan dilakukan dan apasaja barang yang digunakan. (2) pembekalan, memberikan pembekalan melalui sosialisasi di salah satu balai desa RW. Dan (3) pelaksanaan program KKN, melakukan penanaman per RW dengan masing-masing terdapat 10 bibit tanaman TOGA yang terdiri dari tiga bibit tomat, tiga bibit terong dan 4 bibit cabai. Meskipun manfaat TOGA bagi kesehatan telah lama diketahui, penggunaannya terbatas pada ramuan yang dibuat sebagai obat keluarga yang diwariskan secara turun-temurun. Oleh karena itu, perlu dilakukan edukasi kepada masyarakat setempat tentang manfaat tanaman TOGA karena khasiat dan manfaatnya belum diketahui. Namun, belum banyak masyarakat yang mengetahui khasiat tanaman TOGA, oleh karena itu melalui sosialisasi ini, masyarakat akan lebih mampu memahami tanaman TOGA dan bagaimana tanaman tersebut dapat membantu menjaga kesehatan tubuh. Kata kunci: Tanaman; TOGA; Desa Plaosan
BERKEBUN DAN BUDIDAYA IKAN DI KAWASAN PERKOTAAN: APLIKASI BUDIKDAMBER SEBAGAI SOLUSI PENINGKATAN KEMANDIRIAN PANGAN UPAYA MENDUKUNG GREEN ECONOMY
Authors: Karina Indira , Ikhlas Boni , Desmiati Ira , Aisyah Siti , Munzir Abdullah 
Published: January 2025

Abstract: The Lubuk Tempurung Indah Fish Farming Group mainly cultivates tilapia. Since the last 5 years, agricultural land and fish farms in Kuranji Village have been disappearing and replaced by housing complexes. This has caused production from farmers and fish farmers to decline. To overcome this problem, the solution designed is skills training on the technical aspects of BUDIKDAMBER or fish farming in a bucket with a hydroponic system at the top. Assistance in BUDIKDAMBER and hydroponic business management starting from planning, organizing, directing to supervising the products produced and assistance in product marketing through improving marketing strategies by utilizing internet networks or websites (e-commerce). The result of this activity is the emergence of new products resulting from the diversification of the application of Budikdamber science and technology, namely live stalls (vegetables and fruits) and growing TOGA (family medicinal plants) and catfish from Budikdamber. The formation of business management ranging from planning, organizing, directing to supervising the products produced. Partners are able to make well-organized financial and administrative bookkeeping, and are able to market products utilizing the internet network or website (e-commerce).Keywords: BUDIKDAMBER, Hydroponics, Marketing, Business Development. Abstrak: Kelompok Budidaya Ikan Lubuk Tempurung Indah sebagian besar hanya membudidayakan ikan nila. Sejak 5 tahun terakhir lahan pertanian dan budidaya ikan di Kelurahan Kuranji semakin menghilang dan berganti dengan komplek perumahan. Ini menyebabkan produksi dari petani dan pembudidaya ikan semakin menurun. Untuk mengatasi masalah tersebut solusi yang dirancang adalah pelatihan keterampilan pada aspek teknis BUDIKDAMBER atau budidaya ikan dalam ember dengan sistem hidroponik di bagian atasnya. Pendampingan dalam manajemen usaha BUDIKDAMBER dan hydroponic mulai dari perencanaan, pengorganisasian, pengarahan hingga pengawasan terhadap produk yang dihasilkan dan pendampingan pada pemasaran produk melalui peningkatan stategi pemasaran dengan memanfaatkan jaringan internet atau website (e-commerce). Hasil dari kegiatan ini adalah munculnya produk baru hasil diversifikasi penerapan IPTEK Budikdamber yaitu warung hidup (sayur dan buah-buahan) dan menanam TOGA (tanaman obat keluarga) serta lele hasil Budikdamber. Terbentuknya manajemen usaha mulai dari perencanaan, pengorganisasian, pengarahan hingga pengawasan terhadap produk yang dihasilkan. Mitra mampu membuat pembukuan keuangan dan administrasi yang tertata baik, dan mampu memasarkan produk memanfaatkan jaringan internet atau website (e-commerce).Kata kunci: Budikdamber, Hidroponik, Pemasaran, Pengembangan Usaha.