bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social Capital is Positively Associated with Self-rated Health Among Chinese Adolescents
Authors: Wang Xueshuang , Qidi Zhou , Petrušič Tanja , Mieziene Brigita , Novak Dario 
Published: December 2023

Abstract

Background
This study examines the relationship between self-rated health and social capital among Chinese adolescents and aims to understand the influence of family, neighborhood, and school connections on adolescents' perceived health.
Methods
This cross-sectional study involved 501 secondary school students (217 males, 284 females, 15–19 years old). Self-perceived health was rated on a five-point scale divided into 'good health' and 'bad health'. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to assess the association between good self-rated health and social capital in family, neighborhood and school. Gender, self-perceived socioeconomic status, psychological distress and body mass index were considered in the analysis using multivariate logistic regression.
Results
The results indicate a robust correlation between good self-rated health and increased family social capital (OR 2.99; 95% CI: 1.78 to 5.00), increased neighborhood trust (OR 2.42; 95% CI: 1.56 to 3.76), and increased informal social control (OR 1.74; 95% CI: 1.07 to 2.83). Conversely, no statistically significant correlation was found between good self-rated health and school social capital.
Conclusions
These findings underscore the central role of family and neighborhood social capital in shaping the self-rated health of Chinese adolescents. The study highlights the need for a more comprehensive understanding of the specific influences of family and community connections on adolescents' well-being and thus contributes to the broader discourse on adolescent health in Chinese culture.
Proton pump inhibitor induced hypomagnesemia and mortality: mediation analyses in the Diabetes Care System cohort
Authors: Vermeulen E. A. , Rijnhart J. J.M. , Hoekstra T. , Oost L. J. , Baaij J. H.F. , Blom M. T. , Elders P. , Vervloet M. G. , Beulens J. W. 
Published: December 2023

Abstract

Background: Chronic proton pump inhibitor (PPI) use and hypomagnesemia are common in people with type 2 diabetes (T2D), and both are associated with increased mortality and cardiovascular disease (CVD). Since PPI use can cause hypomagnesemia, we investigated if magnesium is a mediator of the association between PPI use and mortality and CVD in people with T2D.
Methods: This study was performed in 4,037 participants of the Dutch prospective Diabetes Care System cohort. Serum magnesium was measured between 2008-2014 and PPI use was determined the year preceding magnesium measurement. The primary outcome was all-cause mortality with follow-up until 2020, and the secondary outcome was fatal and non-fatal CVD. We performed causal mediation analyses.
Results: Mean serum magnesium was 0.80 mmol/l (SD 0.08) and 1,079 (26.7%) participants received PPI treatment. Median follow-up was 7.0 years [IQR 6.4-11.1], 711 (17.6%) participants died, and 608 (15.6%) had a cardiovascular event. PPI use was associated with a low serum magnesium level and an increased incidence of CVD and mortality. The association between PPI use and all-cause mortality was not mediated by magnesium (natural indirect effect (NIE): survival time ratio (STR) 0.99[95%CI 0.98;1.00] and magnesium was only a minor mediator in the association of PPI use and CVD (NIE: STR 0.98[95%CI 0.97;<1.00].
Conclusion: Serum magnesium was not a mediator of the association between PPI use and all-cause mortality. Magnesium explains only a minor part of the total effect of PPI use on CVD. Additional mediators of the association between PPI and adverse outcomes should be explored.
Temporal Changes in Morphology of the Auditory and Vestibular Organs in C57BL/6J (Cdh23ahl/ahl) Mice
Authors: Yokota Shu , Yoshimura Hidekane , Takumi Yutaka 
Published: December 2023

Abstract
C57BL/6J (Cdh23ahl/ahl) mice present with progressive hearing loss (HL) and are homozygous for the Cdh23 gene variant (c.753A), which is responsible for HL in C57BL/6J (Cdh23ahl/ahl) mice. In humans, the CDH23 gene is responsible for syndromic HL, such as congenital severe HL and bilateral vestibular dysfunction in Usher syndrome type 1D (USH1D), and non-syndromic HL, such as DFNB12, which is progressively impaired hearing at high frequencies. However, few reports have simultaneously evaluated temporal hearing function and temporal changes in the morphology of the auditory and vestibular organs. Therefore, we evaluated the transition of hearing and changes in the number of hair cells (HCs) in the cochlea and vestibule over time. Hearing thresholds gradually increased in the high-frequency range from 32 kHz to 16 kHz. At 36 weeks of age, there was also an increase in clicks and 8 kHz thresholds, which reflects the low-frequency threshold. In the cochlea, the number of inner and outer HCs (IHCs and OHCs, respectively) decreased from the basal turn to the apical turn. The number of OHCs decreased prior to that of the IHCs. The number of HCs in the utricles remained unchanged until 60 weeks of age. Our results demonstrate that C57BL/6J (Cdh23ahl/ahl) mice present with DFNB12 features rather than USH1D features.
LAMEE: A Light All-MLP Framework for TimeSeries Prediction Empowering Recommendations
Authors: Xie Yi , Xiong Yun , Gao Xiaofeng , Chen Jiadong , Zhang Yao , Wu Xian , Chen Chao 
Published: December 2023

Abstract
Exogenous variables, unrelated to the recommendation system itself, can significantly enhance its performance. Therefore, integrating these time-evolving exogenous variables into a time series and conducting time series predictions can maximize the potential of recommendation systems. We refer to this task as Time Series Prediction Empowering Recommendations (TSPER). However, as a sub-task within the recommendation system, TSPER faces unique challenges such as computational and data constraints, system evolution, and the need for performance and interpretability. To meet these unique needs, we propose a lightweight Multi-Layer Perceptron architecture with joint Time-Frequency information,named Light All-MLP with joint TimE-frEquency information (LAMEE).LAMEE utilizes a lightweight MLP architecture to achieve computing efficiency and adaptive online learning. Moreover, various strategies have been employed to improve the model, ensuring stable performance and model interpretability. Across multiple time series datasets potentially related to recommendation systems, LAMEE balances performance, efficiency, and interpretability, overall surpassing existing complex methods.
Perspectives of Family Caregivers and Nurses on Hospital Discharge Transitional Care for Muslim Older Adults Living with COPD: A Qualitative Study
Authors: Songwathana Praneed , Jehloh Latifah , Kitrungrote Luppana , Bourbonnais Anne 
Published: December 2023

Abstract

Background The increased number of emergency department visits among older adults with chronic obstructive pulmonary disease reflects the challenges of hospital discharge transition, especially when they are from a cultural minority. The barriers and facilitators of this discharge from the perspective of formal and informal care providers, such as nurses and family caregivers, are important to identify to provide effective symptom management and quality of care. The purpose of this study was to describe the barriers and facilitators in caring for older adults with chronic obstructive pulmonary disease (COPD) during hospital discharge transitional care. Methods A descriptive qualitative study was conducted in a hospital of Thailand where Muslim people are a cultural minority. Thirteen family caregivers of Muslim older adults living with COPD and seven nurses were purposive recruited and participated in semi-structured interviews and focus group discussions. Content analysis was used to analyze the data. Results Five barriers and three facilitating factors of symptom management in the discharge transition for Muslim older adults living with COPD were outlined. Barriers included: (1) lack of knowledge about the causes and management of dyspnea, (2) inadequate discharge preparation, (3) language barrier, (4) discontinuity of care, and (5) COVID-19 epidermic. Facilitators included: (1) the ability to understand Malayu language, (2) the presence of healthcare professionals of the same gender, and (3) the presence of Muslim healthcare providers. Conclusion Family caregivers require more supportive care to meet the care needs of Muslim older adults living with COPD. Alternative nurse-based transitional care programs for these older adult caregivers should be developed.
Development of a Mobile GIS Application (LandInfo) for Land Use and Land Cover Field Data Collection
Authors: Sarbazvatan Amirhossein , Karimi Neamat 
Published: December 2023

Abstract
Land use and Land cover (LULC) is considered one of the most basic data for any country. LULC information is used in many cases such as agricultural management, water resource management, urban planning, environmental management, etc. One of the optimal ways to generate low-cost and fast LULC maps is to use remote sensing and satellite imageries. Generation and accuracy assessment of maps requires accurate and reliable field data. The manual method of collecting field data is a traditional and reliable method that has been widely utilized since the past. Despite the advantages, this method has various limitations such as slow speed and time-consuming, limited forms, lack of control over the information of field users, difficult editing, difficulty entering data into the system and things like that. With the introduction of Global Positioning System (GPS) to mobile phones and the development of location-based applications, the concept of mobile Geographic Information System (GIS) was formed. Using mobile GIS as a tool to collect field data can overcome many limitations of the manual method. Therefore, this study has developed a GIS mobile application called "LandInfo" in order to obtain optimal and appropriate land information for the preparation and evaluation of LULC maps. The development of LandInfo application was accomplished through a process with four stages including needs assessment, application design, application implementation, and application testing. LandInfo is a native application based on the Android operating system, developed with Android and Java. The results of the study with the LandInfo application have increased the speed of the field data collection operation and resolve the limitations of the manual method. Our results demonstrate 22.97% reduction in data collection time and entering the software in a sample survey between the manual method and using LandInfo application.
Productivity and nutritive value of Urochloa brizantha cultivar Piatã, Megathyrsus maximus cultivar Zuri and cultivar Tamani in Silvipastoral Systems in the Central Region of Minas Gerais1
Authors: Teixeira Elaine Cristina , Pereira Walther Malta Coutinho Rezende , de Souza Fernando Antônio , Neto Miguel Marques Gontijo , Silva Edilane Aparecida da , Borges Iran Dias , Lana Ângela Maria Quintão 
Published: December 2023

Abstract

To evaluate the forage yield Urochloa brizantha cultivar Piatã, Megathyrsus maximus cultivar Zuri and the Tamani cultivar, in silvopastoral systems (SSP) with different tree densities and in pasture in full sun (FS), an experiment was carried out in the municipality of Sete Lagoas located in the Cerrado biome in the central region of Minas Gerais. The experimental design was completely randomized, with split-plots in spaceand six replications. The plots corresponded to four spatial arrangements: three silvopastoral system arrangements (SSP) with Eucalyptus grandis GG100 (15×2, 15×4 and 15×8 m) and one grass monoculture. The subplots were composed of three grasses: U. brizantha cv. Piatã, M. maximus cv. Zuri and cv. Tamani. In the subplots, three cuts were made at 20 cm height from the soil surface, with six replications in each. The forage biomass yield and the proportion of leaf and stem components in the forage biomass were evaluated. At tree densities of 166 and 333 trees/ha in the SSPs, pastures suffered significant reductions in whole-plant biomass production, and in the leaves-to-stems ratio in forage when compared to full pasture. On the other hand, at the density of 84 plants per hectare, the production was similar to that in full sun.
A single-valued neutrosophic credibility numbers multi-attribute group decision-making method based on CPT-EDAS and consensus model
Authors: Liu Pingqing , Shen Junxin , Zhang Peng , Ning Baoaquan 
Published: December 2023

Abstract
Purpose –In this paper, we investigate the multi-attribute group decision-making (MAGDM) method for single-valued neutrosophic credibility numbers (SvNCNs), consider a consensus model for group decision-making (GDM) in SvNCN environments, and construct a decision-support system for the evaluation of suppliers of data analysis tools (DAT).
Design/methodology/approach –First, the concept of SvNCNs and the related theory are given, and several dice distance measures for SvNCNs are proposed. Secondly, a consensus model in the SvNCN environment is proposed. At the same time, the subjective and objective weights of attributes are determined by using the AHP method and MEREC method, and the combined weights are calculated based on the Uninorm operator. Then, considering the “limited rationality” behavior of decision makers (DMs), the CPT is integrated into the EDAS method. Finally, an example analysis and comparative analysis are conducted to verify the effectiveness and feasibility of the technique.
Findings –This method enriches the MAGDM theory of SvNCNs by considering group consensus, CPT, and the Uninorm operator to determine the combination weights.
Research limitations/implications –This study contributes to the literature on fuzzy set theory and MAGDM methods, enriching the theoretical and application scenarios of SvNCNs.
Practical implications –This research informs decision information for decision theory for SvNCNs, which applies to several domains, such as MAGDM, large-scale group decision-making, mathematical statistics, and artificial intelligence.
Originality/value –This technique combined the consensus model, CPT-EDAS, and Uninorm operator to enrich the decision theory of SvNCNs.
Understanding wildfire communication: a risk assessment through a new socio-ecological index
Authors: Calvani Silvia , Foderi Cristiano , Paoloni Riccardo , Frassinelli Niccolò , Neri Francesco , Marchi Enrico 
Published: December 2023

Abstract

Background
Wildfires, primarily human-induced phenomena, given the causally relation with the land use and climate conditions, have seen an increase in intensity and frequency since the beginning of the last century, driven precisely by climatic and socio-economic changes. This shift made suppression an insufficient approach, warranting further investigation into the human component of forest fire prevention. Social and environmental factor analysis is useful for weighing the impacts of the factors that influence fire prevention. In this study, we assess communication impacts by analyzing information flows about wildfires and local risk in Italy and Tuscany. Additionally, direct wildfire impacts are evaluated through the examination of the number of wildfires and burned surfaces. The study employs quantitative, qualitative, and statistical methods to analyze the quality and quantity of information dissemination and investigates the relationship between wildfires and media communication to determine wildfire risk. A comparative methodology between the two factors is applied for selecting critical areas.
Results
Results from the communication analysis reveal that 2017 marked the highest peak of reported wildfires in Italy (450), with Tuscany showing the greatest amount of news (233). Wildfire-related news is spread throughout the year, peaking in the dry season (June to September). Statistical analyses, including single-variable, combination, and interaction models, indicate the strongest correlation is between chronicle articles from local newspapers and wildfire events (adjusted R2 ≈ 0.63, p-value ≈ 0.53). While highlighting the limits of considered media types, a common trend is identified, culminating in a risk map highlighting vulnerable areas.
Conclusions
In conclusion, the wildfire risk is intricately determined by both ecological and social parameters. Our results point out communication as a social parameter to gauge regional fire awareness levels. The wildfire vs. communication index facilitates the comparison of ecological and social parameters, identifying critical areas in Tuscany. These findings lay the foundation for future community involvement in a risk perception study, described in a follow-up paper. A paradigm shift that places centrality on social aspects and influences changes in the decision-making process, is needed to face environmental issues. Future studies should expand the consideration of media sources to enhance the comprehensiveness of the analysis.
A synthetic microbiome to promote sulfur utilization: Based on dominant microbes in wild rice rhizosphere
Authors: Wang Changji , Chang Jingjing , Tian Lei , Sun Yu , Wang Enze , Yao Zongmu , Ye Libo , Zhang Hengfei , Pang Yingnan , Tian Chunjie 
Published: December 2023

Abstract
Sulfur (S) is one of the main components of important biomolecules, which has been paid more attention in the anaerobic environment of rice cultivation. In this study, 12 accessions of rice materials, belonging to two Asian rice domestication systems and one African rice domestication system, were used by shotgun metagenomics sequencing to compare the structure and function of rhizosphere microbiome between wild and cultivated rice. Compared with cultivated rice, S-cycling microbial community in wild rice rhizosphere showed higher diversity, closer correlation and lower evenness. Furthermore, the sulfur cycle functional genes were significantly different between wild and cultivated rice rhizosphere in the processes of sulfate reduction and other sulfur compounds conversion, implicating that wild rice had a stronger mutually-beneficial relationship with rhizosphere microbiome. To assess the effects of synthetic microbiomes, the dissimilatory sulfate reduction dominated in wild rice was selected as the direction to improve sulfur utilization in cultivated rice. Comamonadaceae and Rhodospirillaceae, two families containing the genes of two key steps in the dissimilatory sulfate reduction, aprA and dsrA respectively, were isolated to construct the synthetic microbiome. Compared with the control group and the inoculated with different proportions groups, the dissimilatory sulfate reduction in cultivated rice rhizosphere was significantly improved in the inoculated with equal proportions group. It confirmed that the synthetic microbiome can promote the S-cycling in rice, and suggested that may be feasible to construct the synthetic microbiome step by step based on functional genes to achieve the target functional pathway. In summary, this study reveals the response of rice rhizosphere microbial community structure and function to domestication, and provides a new idea for the construction of synthetic microbiome.
Nanonoscapine: A Promising Treatment for Prostate Cancer Through Targeting GLI1 and BAX Expression
Authors: Nazari Mohammad Hossein Derakhshan , Heidarian Ronak , Masoudnia Mina , Dastjerdi Rana Askari , Talkhounche Parnian Ghaedi , Taleahmad Sara 
Published: December 2023

Abstract

Noscapine as an opium-derived phthalide isoquinoline alkaloid has been revealed with anti-turmeric impacts by various mechanisms. Attending to the lower side effects of nano-drugs and their delivery benefits, nanonoscapine is expected to disclose better features. In this study, MTT assay and flow cytometry were performed and revealed that the 50 µg/ml concentration during 48h treats prostate cancer cells appropriately, causing the G2/M arrest and apoptosis. Gene expression analysis using RNA sequencing illustrated a correlation between cancer cell progression and GLI1 and BAX suppression. Also, using qRT-PCR, it was observed that nanonoscapine upregulates GLI1 and BAX in cancer cells. Through computational and Bioinformatics analysis, GLI1 overexpression by nanonoscapine was revealed to disrupt nuclear division during mitosis and arrest cells at the G2/M phase by suppressing the expression of CDK1 and inducing the expression of IRAK3. Besides, BAX upregulation by nanonoscapine was detected to enhance GSK3A and BID expressions which foster BAX function in permeabilizing mitochondrial outer membrane and releasing cytochrome c which leads to apoptosis. Moreover, the Kaplan Meier plot for GLI1, BAX, IRAK3, CDK1, GSK3A, and BID indicated that nanonoscapine can improve prostate cancer patients’ survival times. Nanonoscapine can be used instead of noscapine besides chemotherapy to treat prostate cancer since it targets cancer cells and improve patients’ overall survival.
Prognostic impact of the conditioning intensity on outcomes after allogeneic transplantation for MDS with low blasts: A nationwide retrospective study by the adult MDS working group of the Japan Society for Transplantation and Cellular Therapy
Authors: Itonaga Hidehiro , Miyazaki Yasushi , Fujioka Machiko , Aoki Jun , Doki Noriko , nishida tetsuya , Fukuda Takahiro , Uchida Naoyuki , Ueda Yasunori , Uehara Yasufumi , Katayama Yuta , Ota Shuichi , Kawakita Toshiro , Kato Jun , Matsuoka Ken-ichi , Eto Tetsuya , Onizuka Makoto , Ichinohe Tatsuo , Atsuta Yoshiko , Ishiyama Ken 
Published: December 2023

Abstract

Poor prognostic factors, such as transfusion dependency and chromosomal risk, need to be considered in the indication of allogeneic hematopoietic stem cell transplantation (allo-HSCT) for patients harboring myelodysplastic syndromes with less than 5% marrow blasts (MDS-Lo). We conducted a nationwide retrospective study to clarify the optimal conditioning intensity for MDS-Lo. Among 1,229 patients, 651, 397, and 181 with MDS-Lo received myeloablative (MAC), reduced-intensity (RIC), and non-myeloablative conditioning (NMAC) regimens, respectively. The multivariate analysis revealed that the RIC group had better graft-versus-host disease (GVHD) and relapse-free survival (GRFS) than the MAC group (HR 0.75, 95% CI 0.63–0.89, P = 0.001), while no significant differences were observed between the NMAC and MAC groups. Furthermore, overall survival, chronic GVHD- and relapse-free survival, and the incidence of relapse and non-relapse mortality did not significantly differ among three groups. The RIC group had a lower incidence of acute (HR 0.81, 95% CI 0.68–0.97, P = 0.019) and chronic GVHD (HR 0.79, 95% CI 0.63–0.99, P = 0.045) than the MAC group. In conclusion, the RIC and NMAC regimens are promising options for MDS-Lo patients in addition to the MAC regimen. The careful management of GVHD in MDS-Lo patients receiving the MAC regimen needs to be considered.