bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predatory impacts of invasive Blue Catfish in an Atlantic coast estuary
Authors: Hilling Corbin D. , Schmitt Joseph D. , Jiao Yan , Orth Donald J. 
Published: October 2023

Abstract

Objective
Predatory invasive fishes may consume species of management interest and alter food webs. Blue Catfish Ictalurus furcatus is a large-bodied, salinity-tolerant species that exhibits broad diet breadth and preys on species of both conservation concern and fisheries management interest. To better understand the ecological consequences of the establishment of Blue Catfish fisheries, estimates of predatory impacts are needed.

Methods
Using a Monte Carlo simulation, we integrated abundance estimates, diet information, and consumption-to-biomass ratios to estimate population-level Blue Catfish predation for a large Chesapeake Bay tributary along the mid-Atlantic coast of the United States, the James River.

Result
Population-level annual predation estimates by Blue Catfish exceeded 100 metric tons for several species or taxa of interest, including an estimated 400.7 metric tons (95% CI = 272.6–613.2) of blue crab Callinectes sapidus. Prey species abundances were unknown and thus limited opportunities to evaluate prey population responses. For instance, effects of Blue Catfish on blue crab populations remain unknown without tributary-specific estimates of blue crab abundance, but comparisons to landings data suggests that Blue Catfish predation on blue crab in the James River may be low compared with harvest.

Conclusion
Estimation of Blue Catfish predatory effects may inform development of management goals and objectives that balance diverse stakeholder interests. This work provides beneficial information to assess trade-offs of Blue Catfish fisheries and their effects on coastal aquatic resources.
Misfolded α‐Synuclein in Cerebrospinal Fluid of Contact Sport Athletes
Authors: Vasilevskaya Anna , Martinez‐Valbuena Ivan , Anastassiadis Chloe , Taghdiri Foad , Khodadadi Mozhgan , Tarazi Apameh , Green Robin , Colella Brenda , Wennberg Richard , Mikulis David , Davis Karen Deborah , Kovacs Gabor G. , Tator Charles , Tartaglia Maria Carmela 
Published: October 2023

AbstractBackgroundMisfolded α‐synuclein in Parkinson's disease (PD) and dementia with Lewy bodies (DLB) can be detected using the real‐time quaking‐induced conversion (RT‐QuIC) technique in cerebrospinal fluid (CSF).ObjectivesThe objectives are (1) to examine misfolded CSF α‐synuclein incidence, and (2) to compare clinical presentation, sports history, brain volumes, and RT‐QuIC α‐synuclein positivity in former athletes.MethodsThirty former athletes with magnetic resonance imaging, neuropsychological testing, and CSF analyzed for phosphorylated tau 181 (p‐tau), total tau (t‐tau), amyloid‐β 42 (Aβ42), and neurofilament light chain (NfL). CSF α‐synuclein was detected using RT‐QuIC.ResultsSix (20%) former athletes were α‐synuclein positive. α‐Synuclein positive athletes were similar to α‐synuclein negative athletes on demographics, sports history, clinical features, CSF p‐tau, t‐tau, Aβ42, and NfL; however, had lower grey matter volumes in the right inferior orbitofrontal, right anterior insula and right olfactory cortices.Conclusionsα‐Synuclein RT‐QuIC analysis of CSF may be useful as a prodromal biofluid marker of PD and DLB. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
RAF1 mutation leading to hypertrophic cardiomyopathy in a Chinese family with a history of sudden cardiac death: A diagnostic insight into Noonan syndrome
Authors: Zheng Jingjing , Peng Longyun , Cheng Ruofei , Li Zhiyan , Xie Jianjie , Huang Erwen , Cheng Jianding , Zhao Qianhao 
Published: October 2023

AbstractBackgroundHypertrophic cardiomyopathy (HCM) is predominantly caused by mutations in sarcomeric genes. However, a subset of cases is attributed to genetic disorders unrelated to sarcomeric genes, such as Noonan syndrome (NS) and other RASopathies. In this study, we present a family with a history of sudden cardiac death (SCD) and focus on two adults with syndromic left ventricular hypertrophy (LVH).MethodsClinical evaluations, including echocardiography, were conducted to assess cardiac manifestations. Whole‐exome sequencing was performed to identify potential genetic variants underlying syndromic LVH in the study participants.ResultsWhole‐exome sequencing revealed a missense variant in the RAF1 gene, c.782C>T (p.Pro261Leu). This variant confirmed the diagnosis of NS in the affected individuals.ConclusionThe findings of this study underscore the importance of family history investigation and genetic testing in diagnosing syndromic LVH. By identifying the underlying genetic cause, clinicians can better understand the etiology of RAS‐HCM and its association with SCD in young adults.
Evaluation of modulation of immunity by lymph node transfer: A preliminary histological evidence in lymphedema patients
Authors: Elia Rossella , Chen Hung‐Chi , Cazzato Gerardo , Di Summa Pietro G. , Giudice Giuseppe , Maruccia Michele 
Published: October 2023

AbstractBackgroundThe exact knowledge of the local biological and immunological effects of vascularized lymph node transfer (VLNT) continues to be an emerging science but a positive control positive control over infectious and immune‐mediated processes is often advocated. Knowing the characterization of the inflammatory infiltrate associated with lymphedema, the aim of this paper is to verify the hypothesis that VLNT is able to modulate the inflammatory and immune microenvironment of lymphedematous tissue by evaluating any modification of the local inflammatory cell infiltrate.Patients and MethodsA prospectively database of patients who received VLN transfer for lower extremity lymphedema between January 2018 and December 2020 was reviewed. Nine patients diagnosed with extremities' stage II secondary lymphedema were included, with a mean age of 55.3 (range 39–66 years) years. Gastroepiploic lymph node transfer was performed in all patients and transferred heterotopically. Full thickness 6‐mm skin punch biopsies were obtained from all voluntary lymph node transfer patients at identical sites of the lymphedematous limb during the surgical procedure of VLNT (T0) and 1 year later (T1). Immunohistochemistry was performed using antibodies against the following markers: anti‐CD3; anti‐CD4; anti‐CD8; anti‐CD68. Data at T0 were compared to those at T1.ResultsPost‐operative course was uneventful in all cases experiencing a significant reduction (almost a third) in terms of cellulitis episodes: The median duration of follow‐up for patients was 28.3 months (range 12–40). The analysis of the density of the inflammatory cells as a whole revealed a significant reduction at T1 compared to T0. Specifically, CD3 expression levels turned from 16.36 ± 3.421 (cells/mm2) pre‐operatively to 7.6 ± 1.511 (cells/mm2) post‐operatively (p < .0001). CD4+ cells turned from 7.270 ± 3.421 (cells/mm2) at T0 to 4.815 ± 1.511 cells/mm2 at T1 (p = .0173). CD8 expression values decreased from 4.360 ± 3.421 (cells/mm2) to 2.753 ± 1.451 (cell/mm2) at T1 (p = .0003). Monocyte/macrophage marker CD68 varied from 8.208 ± 2.314 (cells/mm2) at T0 to 7.600 ± 1876 (cells/mm2) at T1 (p = .0003).ConclusionVLNT decreases skin and subcutaneous tissues' infiltration of inflammatory cells, providing one explanation for the positive control of lymph node transfer procedure over infectious and immune‐mediated processes.
An in silico investigation of Kv2.1 potassium channel: Model building and inhibitors binding sites analysis**
Authors: Wang Xiaoyu , Zhang Xinyuan , Zhou Jie , Wang Weiping , Wang Xiaoliang , Xu Bailing 
Published: October 2023

AbstractKv2.1 is widely expressed in brain, and inhibiting Kv2.1 is a potential strategy to prevent cell death and achieve neuroprotection in ischemic stroke. Herein, an in silico model of Kv2.1 tetramer structure was constructed by employing the AlphaFold‐Multimer deep learning method to facilitate the rational discovery of Kv2.1 inhibitors. GaMD was utilized to create an ion transporting trajectory, which was analyzed with HMM to generate multiple representative receptor conformations. The binding site of RY785 and RY796(S) under the P‐loop was defined with Fpocket program together with the competitive binding electrophysiology assay. The docking poses of the two inhibitors were predicted with the aid of the semi‐empirical quantum mechanical calculation, and the IGMH results suggested that Met375, Thr376, and Thr377 of the P‐helix and Ile405 of the S6 segment made significant contributions to the binding affinity. These results provided insights for rational molecular design to develop novel Kv2.1 inhibitors.
Blenderized tube feedings: Practice recommendations from the American Society for Parenteral and Enteral Nutrition
Authors: Epp Lisa , Blackmer Allison , Church April , Ford Ivy , Grenda Brandee , Larimer Cara , Lewis‐Ayalloore Joanna , Malone Ainsley , Pataki Linda , Rempel Gina , Washington Vita ,   The ASPEN Enteral Nutrition Committee
Published: October 2023

AbstractPrior to the 1970s, blending food and liquids and putting them through an enteral access device (EAD) was the most common form of enteral nutrition (EN). However, in the 1970s, blenderized tube feedings (BTFs) became less popular due to the emergence of modern commercial enteral formulas (CEFs). Recently, a cultural shift toward consuming a natural diet, consisting of whole foods, has led to a resurgence in the use of BTF. The increasing use of BTF in a variety of patient care settings identifies a need for practice recommendations that provide guidance for nutrition professionals and patients. Members of the American Society for Parental and Enteral Nutrition (ASPEN) Enteral Nutrition Committee identified salient clinical questions concerning BTF, conducted a comprehensive literature search, and subsequently developed practice recommendations pertaining to the use of BTF. This paper was approved by the ASPEN 2022–2023 Board of Directors.
Last‐mile delivery with drone and lockers
Authors: Boschetti Marco Antonio , Novellani Stefano 
Published: October 2023

AbstractIn this article, we define a new routing problem that arises in the last‐mile delivery of parcels, in which customers can be served either directly at home by a capacitated truck, or possibly with a drone carried on the truck, or in a self‐service mode using one of the available lockers. We investigate four different formulations, and for one of them, we propose a branch‐and‐cut approach. We also discuss some possible variants of the original problem. In the computational experiments, we analyze and compare the performance of the four formulations for the problem and its variants, and we provide some useful managerial insights.
An enhanced arithmetic optimization algorithm for optimal control of reactive power
Authors: Sahay Shuvam , Upputuri Ramanaiah , Kumari Pooja , Kumar Niranjan 
Published: October 2023

AbstractIn this article, an enhanced arithmetic optimization algorithm (EAOA) is utilized to resolve the optimal reactive power dispatch problem (ORPD) of power plants, which is a non‐linear, non‐smooth, complex optimization problem. Typically, it is formulated as a constrained optimal power flow problem. This paper utilizes the gamma distribution to generate initial random solutions, which improves the accuracy of the arithmetic optimization algorithm (AOA). The original mode of deviation of math optimizer accelerated (MOA) is replaced with the improved pattern of change in the prey's energy in Harris Hawk Optimization (HHO), which creates a superior balance between the exploration and exploitation of AOA. This paper implements logarithmic and exponential operators in place of division and multiplication operators, which improves the exploration ability of AOA and also utilizes the gamma distribution in the generation of random numbers, which are essential for the selection of operators in both search phase which enlarges the search area and improves the global optimum solution. A parametric analysis is performed on 10 benchmark functions for nine possible values before selecting the algorithm's initial parameters. A comparative statistical analysis along with Friedman's test is carried out on 23 benchmark functions to test the overall performance as compared to Sine‐Cosine Algorithm (SCA), Swarm‐Salp Algorithm, Grey Wolf Optimization (GWO), and basic Arithmetic Optimization Algorithm (AOA). EAOA is applied to the IEEE 57 bus system for optimal reactive power control. EAOA reports a significant reduction in a power loss of 23.2 MW, which is 18.596% smaller than the system's base case power loss of 28.5 MW as compared to Artificial Bee Colony (ABC), Firefly Algorithm (FA), Bat‐inspired Algorithm (BAT), Cuckoo Search Algorithm (CSA), and Modified Ant Lion Algorithm (MALO) which reports a reduction in a power loss of 14.73%, 15.43%, 15.43%, 16.14%, and 16.14% respectively. EAOA reduces the TVD to 0.76 pu, compared to ABC, FA, BAT, CSA, and MALO, which minimizes the TVD to 0.84, 0.82, 0.88, 0.82, and 0.79, respectively. This proves that EAOA performs better in resolving ORCP problems regarding the quality of solutions and convergence. A detailed comparative statistical analysis of EAOA with CSA, BAT, and WOA (Whale Optimization Algorithm) is conducted in terms of Probability Distribution Functions (PDF) and Cumulative Distribution Functions (CDF), along with the Wilcoxson sign rank test, which proves that EAOA gives the solution with a higher degree of precision.
Differential privacy optimal control with asymmetric information structure
Authors: Zhang Di , Ni Yuan‐Hua 
Published: October 2023

AbstractA linear‐quadratic optimal control is investigated in this article under the differential privacy (DP) philosophy to trade off the performance and privacy of sensitive information, where the two controllers have asymmetric information structure and some prescribed signal needs to be tracked. Note that the system output and tracking signal are always sensitive and easy to be filched by adversaries; thus the DP methodology is explored to protect them. Under DP Gaussian mechanism, the optimal linear controllers are first studied for finite‐horizon and infinite‐horizon problems. Then, the bounds of mean‐square error of steady‐state Kalman filter estimator is provided, and the DP parameter design will be guided that characterizes the privacy of sensitive information. As the DP Gaussian noise will degrade the controlled performance, the degraded performance is quantitatively calculated. Finally, a numerical example is given that shows the efficiency of obtained results.
Cellular senescence in kidney biopsies is associated with tubular dysfunction and predicts CKD progression in childhood cancer patients with karyomegalic interstitial nephropathy
Authors: Knoppert Sebastiaan N , Keijzer‐Veen Mandy G , Valentijn Floris A , van den Heuvel‐Eibrink Marry M , Lilien Marc R , van den Berg Gerrit , Haveman Lianne M , Stokman Marijn F , Janssens Geert O , van Kempen Sven , Broekhuizen Roel , Goldschmeding Roel , Nguyen Tri Q 
Published: October 2023

AbstractKaryomegalic interstitial nephropathy (KIN) has been reported as an incidental finding in patients with childhood cancer treated with ifosfamide. It is defined by the presence of tubular epithelial cells (TECs) with enlarged, irregular, and hyperchromatic nuclei. Cellular senescence has been proposed to be involved in kidney fibrosis in hereditary KIN patients. We report that KIN could be diagnosed 7–32 months after childhood cancer diagnosis in 6/6 consecutive patients biopsied for progressive chronic kidney disease (CKD) of unknown cause between 2018 and 2021. The morphometry of nuclear size distribution and markers for DNA damage (γH2AX), cell‐cycle arrest (p21+, Ki67−), and nuclear lamina decay (loss of lamin B1), identified karyomegaly and senescence features in TECs. Polyploidy was assessed by chromosome fluorescence in situ hybridization (FISH). In all six patients the number of p21‐positive TECs far exceeded the typically small numbers of truly karyomegalic cells, and p21‐positive TECs contained less lysozyme, testifying to defective resorption, which explains the consistently observed low‐molecular‐weight (LMW) proteinuria. In addition, polyploidy of TEC was observed to correlate with loss of lysozyme staining. Importantly, in the five patients with the largest nuclei, the percentage of p21‐positive TECs tightly correlated with estimated glomerular filtration rate loss between biopsy and last follow‐up (R2 = 0.93, p < 0.01). We conclude that cellular senescence is associated with tubular dysfunction and predicts CKD progression in childhood cancer patients with KIN and appears to be a prevalent cause of otherwise unexplained CKD and LMW proteinuria in children treated with DNA‐damaging and cell stress‐inducing therapy including ifosfamide. © 2023 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.
A simple and effective method to adjust the size of micropores on the inner surface of Polyvinylidene fluoride hollow fiber membranes
Authors: Xiang Li , Yuanyuan Mei , Zhonglin Cao , Shuhao Qin 
Published: October 2023

AbstractPore‐forming agents affect phase thermodynamics of solution‐case membranes, hence influencing the structure and properties of the membrane. Polyvinylidene fluoride (PVDF) membrane has many advantages, but more in‐depth research is needed regarding directional control of membrane pore size. To solve this problem, a simple and efficient method is proposed. By adjusting the percentage of polyvinylpyrrolidone (PVP) in the casting solution, pore diameter is controlled between 0.01 and 10 μm. The number density and diameter of the inner surface increased significantly with increasing PVP content. The relevance of this study lies in the modulation of the inner surface micropore size of PVDF hollow fiber membranes in a simple and efficient procedure.Highlights
Adjusting the size of micropores on the inner surface.
The size range of the inner surface is controlled between 0.01 and 10 μm.
It is possible to regulate the pore structure by limiting PVP concentration.
Significant increase in the number and size of pore on the inner surface.
A simple method for regulating the size of micropores.
Partnership with a school system to implement an Africentric rites of passage program for middle school Black boys
Authors: Williams Otis , Davis Julius , Cox Mark 
Published: October 2023

AbstractThis article shares how three African‐centered Black men partnered with a school system to develop and implement an Africentric rites of passage program for seventh‐ and eighth‐grade Black male students. The proposed school‐based intervention aimed to socialize, educate, and cultivate Black boys in preparation for manhood. Theoretically, the conceptual framework was anchored in African paradigms from Afrocentricity, Kawaida, and Pan‐Africanism. The authors provided an overview of the program, which included the program structure, activities, and events. We concluded with a discussion of program challenges and recommendations for future research and program implementation.
Relationship between the principal's restrictive behavior and preschool teachers' turnover intention: A serial mediation model
Authors: Guo Liping , Yang Enze , Gao Xiaoqiang , Ma Derui 
Published: October 2023

AbstractImproving the management of principals has been proven to be an effective strategy to reduce preschool teachers' turnover. However, relevant empirical evidence for preschool teachers is still insufficient. A total of 3623 preschool teachers from the Chinese mainland participated in the current study through random cluster sampling and were administered self‐report questionnaires to measure their principal's restrictive behavior, work–family conflict, effort–reward imbalance (ERI), and turnover intention. This study used serial mediation models to examine the direct relationship between the principal's restrictive behavior and preschool teachers' turnover intention, as well as the indirect relationship between the two variables through the independent and serial mediating roles of ERI and work–family conflict (including work‐to‐family conflict [WFC] and family‐to‐work conflict [FWC]). Results showed that among Chinese preschool teachers, (1) the direct relationship between the principal's restrictive behavior and turnover intention was significant; (2) ERI mediated the relationship between the principal's restrictive behavior and turnover intention; (3) WFC and FWC both mediated the relationship between the principal's restrictive behavior and turnover intention; and (4) a serial mediating effect of ERI and WFC/FWC was observed. The findings have theoretical and practical significance for interventions to reduce preschool teachers' turnover.
Synthesis of well‐defined methacrylate copolymers and their use for stabilizing membrane proteins
Authors: Monjal Valentin , Moreno Alexis , Glueck David , Keller Sandro , Guillet Pierre , Durand Grégory 
Published: October 2023

AbstractWe describe the synthesis of a novel series of amphiphilic methacrylate copolymers composed of one hydrophobic monomer carrying a cyclohexyl group and one hydrophilic monomer carrying a short poly(ethylene glycol) chain comprising 6, 9, or 19 units. RAFT polymerization was used to yield well‐defined polymers. First, we studied the kinetic of this copolymerization and calculated the reactivity ratios according to different linear least‐squares (LLS) methods. We thus could demonstrate the statistical copolymerization of the two monomers. Then, by varying the ratio of each monomer in the copolymerization, we developed a series of polymers that were tested for their abilities to extract membrane proteins from Escherichia coli cells overexpressing the Bacillus subtilis multidrug resistance ABC transporter (BmrA) and to stabilize the light‐driven proton transporter bacteriorhodopsin (bR). While our copolymers failed to directly extract significant amounts of proteins, they were found to provide stabilizing environments for extracted membrane proteins, suggesting they could be used as non‐ionic stabilizing polymers.
Entropic barrier theory of polymer melting
Authors: Muthukumar Murugappan 
Published: October 2023

AbstractWe present a theory of melting kinetics of semicrystalline polymers at temperatures above the equilibrium melting temperature, by accounting for conformational entropy of chains during melting. We have derived free energy landscapes for escape of individual chains from a lamella into the amorphous phase as a function of the characteristics of the initial lamella, such as the lamellar thickness, number of chain folds, fold‐ and lateral‐surface free energies, and mean energy of a monomer inside the lamella. We show that melting of lamellae is always accompanied by a free energy barrier which is entirely entropic in origin. In terms of the parameters characterizing the lamellae and the extent of superheating, closed‐form formulas are presented for the equilibrium melting temperature, driving force for crystallization, free energy barrier height, average expulsion time of a single chain from a lamella, and the melting velocity of lamellae. The present entropic barrier theory predicts that the dependence of melting velocity on superheating is nonlinear and non‐Arrhenius, in qualitative agreement with experimental observations reported in the literature. The derived formulas open an opportunity to further explore the role of various molecular features of semicrystalline polymers on their melting kinetics.