bluuebunny/crossref_metadata_2025_split huggingface dataset:
Siklopiroks olamin topikal pada onikomikosis rekalsitran yang disebabkan Aspergillus spp.: sebuah laporan kasus
Authors: Mahariski Pande Agung , Karna Ni Luh Putu Ratih Vibriyanti , Winaya Ketut Kwartantaya , Wirya Andrew Yoshihiro 
Published: November 2023

Background: Aspergillus spp., Scopulariopsis spp., Alternaria spp., Acremonium spp. and Fusarium spp. is reported to be responsible as the causative agent of infection in 2-25% of all cases of onychomycosis. The resistance of three types of azole (triazole) antifungals has increased in cases of infection due to Aspergillus spp. This case report discusses combining ciclopirox olamine and fluconazole in recalcitrant onychomycosis due to Aspergillus spp. as an alternative therapy.
Case: A 26-year-old woman complained of yellow fingernails 1 year ago. Solitary geographic hyperpigmented macule, brownish yellow onychodyschromia, onycholysis and subungual debris were observed on the fourth digit of the left manus. On examination of 20% potassium hydroxide, long hyphae, and saboraoud dextrose agar (SDA) culture identified Aspergillus spp. Previous treatment was itraconazole 4 pulses and fluconazole 150 mg/week for 3 months showed no improvement. Ciclopirox olamine for 4 months combined with fluconazole 150 mg/week showed healthy nail matrix growth and negative fungal element on a 20% potassium hydroxide examination after 8 weeks of treatment.
Conclusion: Recalcitrant onychomycosis can occur due to resistance to azole antifungals. Administration of topical azoles and ciclopirox combination therapy showed clinical and immunological improvements.

Latar belakang: Aspergillus spp., Scopulariopsis spp., Alternaria spp., Acremonium spp. dan Fusarium spp. merupakan kapang nondermatofita tersering yang dilaporkan bertanggung jawab sebagai agen penyebab infeksi pada 2-25% dari semua kasus onikomikosis. Saat ini resistensi tiga jenis antijamur golongan azol (triazol) meningkat pada kasus infeksi akibat Aspergillus spp. dan terapi inadekuat dapat menyebabkan resistensi dan rekurensi. Laporan kasus ini membahas penggunaan kombinasi siklopiroks olamin dan flukonazol pada onikomikosis rekalsitran karena Aspergilus spp. sebagai terapi alternatif.
Kasus: Seorang perempuan 26 tahun mengeluh kuku jari tangan menguning sejak 1 tahun lalu. Pada digiti IV manus sinistra didapatkan makula hiperpigmentasi soliter bentuk geografika, onikodiskromia kuning kecoklatan, onikolisis dan subungual debris dengan pemeriksaan kalium hidroksida (KOH) 20% ditemukan hifa-hifa panjang dan kultur saboraoud dextrose agar (SDA) teridentifikasi Aspergillus spp. Riwayat terapi sebelumnya dengan itrakonazol 4 denyut dan flukonazol 150mg/minggu selama 3 bulan tidak menunjukkan perbaikan. Siklopiroks olamin selama 4 bulan dengan melanjutkan flukonazol diberikan dan menunjukkan perbaikan matriks kuku normal dan KOH negatif setelah 8 minggu perawatan.
Simpulan: Onikomikosis rekalsitran dapat terjadi karena adanya resistensi terhadap antijamur golongan azol. Pemberian terapi kombinasi golongan azol dan siklopiroks topikal menunjukkan perbaikan klinis serta imunologis.
The association between achieve of full feeding with mortality in children at sanglah hospital
Authors: Sihombing Rina Margareth , Sidiartha I Gusti Lanang , I Gusti Ayu Eka Pratiwi  
Published: November 2023

Background: For pediatric patients who are hospitalized, full feeding nutritional needs is not only to improve BMI but also very useful for accelerating the healing process, shortening the treatment period, reducing complications, reducing morbidity and mortality, and preventing malnutrition due to treatment or medical action. This study aimed to describe the association between the achievement of full feeding with mortality in children.
Method: The retrospective study was conducted in Pediatric Ward at Sanglah General Hospital, Denpasar Bali period January to December 2021. The inclusion criteria in this study were all pediatric patients who were hospitalized at pediatric wards Sanglah Hospital Denpasar. Inclusion criteria were children aged 1 month-18 years old. Samples were taken by total sampling. Quantitative variables were tested using variables that scale categorical data will be displayed in the form of absolute numbers and percent. The results of the descriptive analysis are presented using a chi-square test used to analyze all indirect variables (depending on whether the assumptions were met). The results of multivariate analysis were with logistic regression. The results were considered statistically significant at p < 0.05.
Result: Total 258 subjects who met the inclusion criteria. Multivariate analysis with logistic regression shows full feeding (Exp B 0.24; 95% CI 0.032-0.27; P 0.006), nutritional status (Exp B 0.23; 95% CI 0.31-1.55; P 0,004) was statistically significant for mortality.
Conclusion: Full feeding and nutritional status were associated with an increase in child mortality.
Perbandingan penanganan operatif dengan non operatif pada tatalaksana dislokasi bahu anterior terhadap rekurensi: systematic review
Authors: Ardhaswari Made Sabrina Prativa Prasaditya , Astawa Putu , Asmara Anak Agung Gde Yuda 
Published: November 2023

Background: Shoulder dislocations are very prone to recurrent shoulder dislocations, the best treatment for reducing recurrence is controversial in several studies. Thus, the aim of this study was to compare operative and nonoperative management of anterior dislocation of the shoulder against recurrence.
Method: The literature search used PubMed and Google Scholar databases and met the inclusion criteria from 2010-2020 regarding the comparison of operative and non-operative treatment on anterior shoulder dislocation on recurrence. This systematic review was prepared by using the PRISMA protocol (Preferred Reporting Items for Systematic Reviews and Meta-Analyzes).
Result: Five studies were reviewed with a total sample size of 635 samples. Three studies stated that the recurrence rate for operative was 10-13% and non-operative was 41-71% and there was a significant difference. Meanwhile, two other studies stated that there was no significant difference between operative and non-operative on recurrence rates.
Conclusion: Studies suggest that non-operative management recurs more frequently in shoulder dislocation than operative management.

Pendahuluan: Dislokasi bahu sangat rentan untuk terjadi dislokasi bahu berulang (recurrent). Hingga saat ini, penanganan yang terbaik dalam menurunkan rekurensi masih bersifat kontroversial dalam beberapa studi. Untuk itu, tujuan dari studi ini adalah untuk membandingan penanganan operatif dengan non operatif pada tatalaksana dislokasi bahu anterior terhadap rekurensi
Metode: Pencarian literatur menggunakan database PubMed dan Google Scholar, serta memenuhi kriteria inklusi dari tahun 2010-2020 mengenai perbandingan operatif dan non operatif pada dislokasi bahu anterior terhadap rekurensi. Penulian systematic review ini disusun menggunakan protocol PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses).
Hasil: Lima studi yang diulas dengan jumlah sampel sebanyak 635 sampel. Tiga studi menyebutkan recurrence rate pada operatif sebesar 10-13% dan non operatif sebesar 41-71% dan terjadi perbedaan yang signifikan. Sedangkan, dua studi lainnya menyebutkan recurrence rate pada operatif dan non operatif menunjukkan tidak ada perbedaan yang signifikan.
Kesimpulan: Keseluruhan studi menyebutkan bahwa penanganan non operatif lebih sering mengalami rekurensi pada dislokasi bahu dibandingkan dengan penanganan operatif.
Materials come around and go around: Adapting to nature’s circularity
Authors: Schüpfer Dominique , Wagner-Wenz Ronja , Hendrich Katharina , Weidenkaff Anke 
Published: November 2023

AbstractThe present multiple crises, such as climate change, war, and the recent pandemic, highlight the need for a stable and secure resource supply chain to overcome resource scarcity and shortages in manufacturing as well as in goods for everyday needs. Today’s linear production chains and waste management systems contribute to disruptions in resource availability as well as to greenhouse gas emissions. The concept of a holistic circular economy, inspired by natural processes, could help to mitigate these challenges. With a primary goal of maintaining resources, as much as possible, in “closed loops,” the following three challenges should be addressed: (1) Dissipation of resources, (2) Irreversibility of some processes, and (3) Logistical, technological, and information. These challenges can be addressed, in part, by implementing computational technology and cascading mechanical and chemical recycling processes in waste and resource management. This article emphasizes the interconnection between resource scarcity and pollution and climate change, and proposes a holistic circular economy as an important contribution to addressing this challenge. This holistic circular economy can be inspired, in part, by nature’s self-healing, self-transformation, and self-disintegration capabilities. Another crucial part is a comprehensive understanding of the limited resources of the planet and the impact on the planet of using up these resources and, thereby, leading to a shift toward sustainable material use and waste management. The transition to a circular economy requires changes at many levels, encompassing materials research, technical engineering, industrial implementation, and societal adaptation. In both product and process development, regardless of the technological readiness level, life-cycle analyses must be performed that consider the impact on the planet. With the help of a “product passport,” a suitable legal framework can be created and implemented. Radical changes in the way we carry out research into technologically relevant materials can pave the way to a holistic circular economy.
Refining Methodological Reflection: Exploring the Interviewing Experience of Oocyte Donors
Authors: Gramatchikova Natalya B. , Polyakova Irina G. 
Published: November 2023

The article reflects on the collaborative experience between a practicing psychologist actively involved in the oocyte donation protocol (participating in guide development, conducting interviews, and drawing conclusions for the clinic) and a philologist who interprets the interview transcripts using narrative and communicative situation analyses. The article begins by describing the interviewing process, the structure of the oocyte-donor guide, and the profile of a “stable donor,” drawing from Russian-language materials. Through narrative analysis of 21 transcripts, the roles of the interviewer and informant at each stage of the interview process are identified, along with their contributions to the discussion and testing of the communicative situation. The paper investigates both the instances of cooperation and discrepancies observed among the participants as they strive to construct a credible and value-consistent autobiographical narrative that comprehensively encompasses their donation experience. The article analyzes both explicit and hidden narrative motives placed by informants in a conversation unfolding from the respondent’s past into a projected future. The authors aim to situate this experience within a broader personal value context, which includes compensatory aspects related to the pressing concerns of potential donors.
Correlation of axial length with minimal effective volume of peribulbar block
Authors: Gupta Kanav , Kritika  , Gupta B.K. , Soni Tarun 
Published: November 2023

Cataract remains the most common cause of blindness worldwide and surgery is the only option to get rid of a cataract. Good anaesthesia is an essential requirement for performing safe cataract surgery. Peribulbar block using regional anaesthetic is the most common technique of administrating anaesthesia for cataract extraction. The study aimed to know the relationship between the axial length and the minimal effective volume of the peribulbar block. The study was done in a hospital based in the rural area of Panipat. It was a cross-sectional study done on patients who underwent cataract surgery and met the inclusion and exclusion criteria of the study. The patients were divided into two groups based on axial length and were given peribulbar block using 2% lignocaine with 1500 IU of hyaluronidase of 6 ml and 8 ml. The subsequent doses of the block were given in those in which adequate response was not present. The study includes 100 patients divided into two groups. The patients in group 1 had axial lengths between 21-23.99 mm and the second group included patients with axial lengths of 24-26.99 mm. In group 1 the volume of peribulbar block given was higher than that in group 2. The maximum number of patients in group 1 (34) were given an 8 ml block and those in group 2 were given a 6 ml of block. The study had a p-value of 0.02. In our study, we found that axial length has a negative correlation with the volume of the peribulbar block. It was also seen that there was an increase in IOP with more amount of local anaesthetic used in the peribulbar block.
The Frequency of Fabry Disease in Acute Stroke Patients with Renal Insufficiency in Sakarya Province
Authors: SAYAN Saadet , KOTAN Dilcan , ÇİÇEKLİ Esen , ALEMDAR Murat 
Published: November 2023

Aim: This study aimed to investigate the frequency, clinical and genetic characteristics, and therapeutic options associated with Fabry disease (FD) in individuals with acute stroke and concomitant renal insufficiency.
Material and Methods: An FD screening was performed on adult patients with renal dysfunction who were admitted to the neurology clinic due to acute stroke between 2015 and 2021. Screening was performed by a leukocyte α-galactosidase A (α-Gal A) enzyme activity assay using dried blood spot (DBS) samples from male patients. In cases where the enzyme activity was less than 2.5 nmol/ml/h, genetic analysis was performed. Female patients underwent direct genetic analysis.
Results: Renal dysfunction was detected in 39 ischemic stroke patients and 5 hemorrhagic stroke patients out of a total of 401 cases. The enzyme level was found low in only one of the male patients. The c.680G>A (p.R227Q) mutation was observed in this male patient and a female patient. In the later stages of the study, it was realized with the help of pedigree analysis that these two cases were first-degree relatives. The same mutation was also detected in 13 first-degree and 2 second-degree relatives. The frequency of FD in our study group, which included patients with cerebral and renal involvement regardless of consanguinity, was 4.54%.
Conclusion: Rapid detection of FD cases can be achieved by screening individuals presenting with multiple end-organ damages. To the best of our knowledge, this study highlights the underemphasized association between renal involvement and stroke in FD.
Disertaciones
Authors: Izaquita Torres Julio Cesar 
Published: November 2023

El corpus documental aquí reunido constituye un hallazgo de archivo inédito en la historia de le educación colombiana del siglo xix, se trata de una serie de "composiciones" que fueron redactadas por los aspirantes a maestros de escuela elemental y secundaria en sus exámenes de graduación de la Escuela Normal de Cundinamarca, la más sobresaliente de las que se abrieron en Colombia desde 1871. A través de estos discursos entusiastas y cargados con el optimismo propio de los primeros graduados en las escuelas de formación de maestros de una época que quiso ser de renovación republicana, leemos a la vez las expectativas de quienes promovieron este programa educativo de alcance nacional, la distancia creciente que nos separa de ellos y la herencia posible que se formula en estas letras vibrantes, lucidas e ilustradas, como las quisieron los pedagogos formadores de esta generación de maestros.
Formas y expresiones metodológicas en el último Foucault
Authors: Pulido Cortés Óscar , Espinel Bernal Óscar Orlando 
Published: November 2023

Un libro sobre Foucault y su incidencia en la investigación y la pedagogía, es una apuesta por pensar la actualidad, el presente y las resonancias de un pensamiento, actualizar es utilizar su pensamiento para construir problemas o situaciones de problemas. Lo importante de trabajar con Foucault hoy es saber qué se puede hacer con su pensamiento y de su pensamiento, es estar inmersos en una actitud, la actitud crítica y ser fieles a ella. La invitación de Foucault siempre fue usar sus libros como cajas de herramientas, que todos puedan emprenderlos de acuerdo con sus necesidades, opciones, reparos y reflejos, ellos pueden ser utilizados para la comprensión de los fenómenos, la conceptualización y las batallas de orden político. Por esta razón no existe un único y universal Foucault, existen varias y múltiples formas de utilizarlo, es un pensamiento 'metodológico', estratégico que posibilita combatir la sumisión y dominación y permite asumir líneas de fuga, formas de contraconductas y prácticas de libertad, en un movimiento continuo de descentramiento y nueva ubicación conceptual y teórica.
Paipa, imágenes y testimonios: matices del pasado. Una revisión desde 1870-1970. Aspectos del territorio
Authors: Díaz Márquez Francisco Benicio , Hernández Plazas Ligia , Andrade Lee Juan Pablo 
Published: November 2023

Este libro ha sido el resultado del proyecto financiado por la Vicerrectoría de Investigaciones de la Universidad Pedagógica y Tecnológica de Colombia, con el apoyo del grupo Ires y la Fundación Paipa Bicentenario; con el fin de reflexionar sobre lo que comprende a la identidad Paipana, se realizan visitas a familias tradicionales paipanas que tuvieren en su acervo material fotográfico y las personas que se destacaron durante su labor en múltiples oficios y profesiones para su aporte y conocimiento de actividades importantes en Paipa. Se recalcan nombres como los de Cecilia Rodríguez de Lee, Jonás Espejo, Genara Vásquez de González, Gustavo Sandoval, Pedro Guatibonza, Rosa Elvira Larotta de Fonseca, Sofía Escobar de Joya, Gerardo Alfonso Alvarado, Carlos Arturo Vásquez Higuera. Personas que partieron a la eternidad en el proceso de realización de esta investigación y durante la edición de este libro.
Caracterización y aplicación del emprendedor y la innovación
Authors: Blanco Mesa Fabio 
Published: November 2023

El emprendimiento es considerado uno de los impulsores fundamentales de la evolución económica y la prosperidad, las cuales dependen de los lugares donde se genera ya que se encuentra influenciado por la trayectoria de la estructura industrial, las instituciones y la cultura. En ese sentido, esta obra nos da a conocer desde diversos enfoques sobre la actividad e las Pymes, el emprendimiento y la innovación en Boyacá. Así, podemos encontrar las diversas estrategias institucionales que fomentan el emprendimiento desde el programa de administración de empresas de la UPTC. También se presenta una descripción del tejido empresarial de las Pymes del corredor industrial de Boyacá. ..
Cultura política y subalternidad en América Latina
Authors: Sanders James , Banerjee Ishita , Dube Saurabh , Conde Calderón Jorge , Prado Arellano Luis Ervin , Murray Pamela S. , Dotor Robayo María Victoria 
Published: November 2023

Cómo escribir una historia que incluya a la gran mayoría de personas que vivieron en el pasado? Por medo siglo esta pregunta ha tenido una cierta urgencia, no sólo por razones historiográficas sino también porque la respuesta ha sido considerada central en los proyectos que buscan ganar la inclusión en la sociedad de grupos sociales previamente excluidos. En la década de 1960 la historia social creció rápidamente y tuvo bastante éxito en ayudar a nuestra comprensión de muchos grupos sociales, como los esclavos, las mujeres y los obreros, especialmente en lo tocante a su vida cotidiana y sus labores. Sin embargo, estas personas que entraron en la historia social raramente aparecieron en la historia política, salvo en resistencia a la política dominante.
Pengaruh Kualitas Layanan, M-Banking dan Nilai-Nilai Islam terhadap Loyalitas Nasabah dengan Kepuasan Sebagai Variabel Intervening (Studi pada Bank Tabungan Negara Syariah KC Solo)
Authors: Muhamad Thoriq Vasluki  , Trishananto Yudha 
Published: November 2023

Penelitian ini bertujuan untuk mengetahui pengaruh Pengaruh Kualitas Layanan M-Banking, Dan Nilai-Nilai Islam Terhadap Loyalitas Nasabah Dengan Kepuasan Sebagai Variabel Intervening (Studi pada Bank Tabungan Negara Syariah KC Solo). Penelitian ini adalah jenis penelitian kuantitatif data primer. Metode pengumpulan data dilakukan dengan menyebar kuisoner pada Bank Tabungan Negara Syariah KC Solo sebanyak 100 responden. Data yang diperoleh menggunakan alat analisis SPSS 25. Analisis yang digunakan atau dipakai dalam penelitian ini meliputi uji instrument penelitian, uji statistic, uji asumsi klasik, analysis path, hasil penelitian ini menunjukan kualitas layanan M-Banking tidak signifikan terhadap loyalitas nasabah,Nilai-nilai Islam tidak berpengaruh signifikan terhadap loyalitas,kualitas layanan M-Banking berpengaruh signifikan terhadap kepuasan,Nilai-Nilai Islam berpengaruh signifikan terhadap kepuasan.
Kata Kunci: Kualitas Layanan M-Banking, Nilai-Nilai Islam, Kepuasan, Loyalitas.
Un format de cours structuré améliore la performance globale en biologie cellulaire mais ne réduit pas l’échec à l’examen final
Authors: Kramer IJsbrand , Pellerin Frédérique , Noguès Xavier 
Published: November 2023

Le passage de l'enseignement secondaire à l'enseignement supérieur reste problématique, étant donné les faibles taux de réussite dans les matières scientifiques, en particulier dans les universités non sélectives. L'adaptation à une nouvelle façon d'enseigner et le fait de se perdre dans la foule sont des facteurs qui entrent en jeu. Nous avons essayé de faciliter la transition vers l'enseignement supérieur en créant un module de biologie cellulaire à structure modérée. Ce module se caractérise par des activités de groupe, un contrôle continu important et une pondération réduite de la note de l'examen final. Dans ce format, le contrôle de l'apprentissage passe progressivement de l'enseignant à l'étudiant. Une comparaison entre quatre années de cours conventionnels et quatre années de cours à structure modérée a montré que ces derniers ont permis d'obtenir des notes supérieures de 8 % et un taux de réussite supérieur de 5 %. Cependant, l'amélioration globale des performances dépend largement des notes obtenues lors du contrôle continu ; nous n'avons pratiquement pas constaté d'amélioration lors de l'examen final. Nous y voyons le signe qu'en dépit de résultats initiaux encourageants, un nombre important d'étudiants ne réussissent pas à passer à l'apprentissage autorégulé.