bluuebunny/crossref_metadata_2025_split huggingface dataset:
A new perspective on trends in psychology
Authors: Zagaria Andrea , Lombardi Luigi 
Published: October 2023

Abstract

The current paper aimed to analyze the trends and prominence of four major schools of thought in scientific Psychology (neuroscience, cognitivism, behaviorism, psychoanalysis) and their intersections, covering the period from 1979 to 2020. We utilized an improved methodology across three distinct sources: mainstream psychology, highly influential journals, and non-English papers. Our findings align with previous research in several aspects: a) psychoanalysis and behaviorism have significantly declined, b) cognitivism remains a prominent trend. However, we deviate from prior studies in the following ways: c) neuroscience may be considered the most influential trend, d) trends exhibit more stability and dispersion than previously assumed, and e) relative stability is observed in psychological studies over the past four decades. We also acknowledge the significance of non-English papers (NEP), which manifest an independent pattern as compared to the other sources and that may reveal what happens in the “periphery” of Psychology. It is noteworthy NEP demonstrated a still lively contribution from psychoanalysis. Overall, our study supports the inference that scientific Psychology is a non-paradigmatic or pre-paradigmatic discipline. It also supports the dominance of applied psychology, confuting the notion of overarching "grand theories." It eventually highlights the insularity and lack of cross-fertilization among psychological subdisciplines, despite the widespread claims to the contrary.
Optimization of A Rapid Spinach Decellularization Technique using Tween-20 with Antibacterial and Wound Healing Properties
Authors: Ksouri Rihab , Aksel Hamide , Saghrouchni Hamza , Saygideger Yasemin 
Published: October 2023

Abstract
Creating acellular constructs with vascularized structure from animal and plant tissue is one of the well-known strategies for scaffold assembly. One of these approaches is decellularization, and the used process for this method varies according to the nature of the tissue and its composition. The most common method is the chemical decellularization of plants. This method employs various high doses of detergents, primarily Triton X-100, sodium dodecyl sulfate (SDS), and sodium hypochlorite (SH). In this study, detergents, which are available in most of the laboratories were compared to develop new methods of spinach decellularization. Tween-20, SDS and SH in minimal concentrations were used to decellularize spinach leaves as an acellular plant matrix for tissue engineering. The samples divided in two different temperature conditions, and decellularization was proven by different analyses such as DNA and protein extraction and quantification and hematoxylin and eosin staining. The antibacterial activity was assessed to choose the most potential group. Two groups with the lowest DNA and protein amounts and high vasculature were chosen for the in vitro experiment. MTT and Scratch assay were used to evaluate the biocompatibility and ability of the bioconstructs to promote wound healing on fibroblasts. The results show that the Tween-20 decellularized samples at concentrations of 1% at 21°C and 37°C had the best morphology and clear vascularization with a high biocompatibility. Also, all of the scaffold samples are very good at killing S. aureus bacteria, which means they can help keep wounds from getting infected while they heal. This indicates they could be used as a scaffold for tissue engineering purposes.
Oral health knowledge, attitudes, and practices of pregnant women in South China: a cross-sectional prenatal survey
Authors: Lin Xiaojie , Jiang Lanlan , Pang Zhenhua , Wang Sumei , Tao Renchuan , Zeng Qixin , Ya Zuke , Peng Yuanyuan , Huang Yuxiao , Su Juanxiu 
Published: October 2023

Abstract
Background
The physiological changes that occur during pregnancy make women more susceptible to oral diseases. The oral health of pregnant women is closely associated with the health of their new-borns. This cross-sectional survey aimed to evaluate the oral health knowledge, attitudes, and practices (KAP) of pregnant women in South China.
Methods
From June 2016 to June 2017, pregnant women visiting the First Affiliated Hospital of Guangxi Medical University and Hospital of Stomatology, Guangxi Medical University were administered a cross-sectional survey on oral health.
Results
In the survey, more than 90% acknowledged the importance of brushing and gargling, while approximately half were aware of the benefits of fluoride (48.36%) and pit and fissure sealant (50.29%). Older women residing in local towns, who had higher levels of education and income, and who possessed medical insurance covering dental care, demonstrated better oral health knowledge in various areas (all P < 0.05). Only 9.28% underwent regular oral check-ups before pregnancy. The primary reason cited for refusing oral check-ups before pregnancy were the lack of dental issues (51.84%) and insufficient time (30.56%). In addition, a large proportion (87.23%) of pregnant women brushed their teeth at least twice a day, while some also flossed (17.79%) and gargled (43.71%) to maintain their oral hygiene.Most pregnant women obtained oral health information from books and newspapers (50.10%), online media (48.55%), and medical professionals (45.65%).
Conclusions
In conclusion, most pregnant women demonstrated good KAP in regard to general oral health. However, several influencing factors, such as age, residency, education level, household income, and medical insurance might affect the KAP of pregnant women concerning their oral health.
Nitrogen-doped carbon dots@COFBTH-TT composite for high-performance lithium ions battery anode
Authors: Li Yuan , Chen Kaixiang , Yu Hao , Song Yonghai , Du Yan 
Published: October 2023

Abstract
Herein, a novel hollow rod-like composite was obtained by doping nitrogen-doped carbon quantum dots (NCDs) into covalent organic frameworks (COFs) (NCDs@COFBTH−TT) by a one-pot hydrothermal method. Such a hollow structure not only facilitates the transport of Li+, but also exposes a large number of active sites. The doped NCDs improves the electrical conductivity of NCDs@COFBTH−TT. When NCDs@COFBTH−TT was applied as the anode materials of lithium-ion batteries (LIBs), it showed excellent Li-storage performance. At a current density of 0.2 A g− 1, the NCDs@COFBTH−TT exhibited an initial capacity of 336.8 mAh g− 1 and then stabilized at 210.7 mAh g− 1 after 226 charge/discharge cycles. This work combines zero-dimensional NCDs with two-dimensional COFs to improve the electrical conductivity and π-π stacking interaction of COFs, which is of great significance for the construction of COFs-based LIBs with high storage capacity and ultra-long cycle life.
Functional investigation and two-sample Mendelian randomization study of non-alcoholic fatty liver disease hub genes obtained by WGCNA
Authors: Yang Yunchuan , Ma Xiang , Zhou Chi , Xu Nan , Ding Ding , Ma Zhongzheng , Zhou Lei , Cui Peiyuan , Liu Mulin 
Published: October 2023

Abstract
Objective: Non-alcoholic fatty liver disease (NAFLD) poses significant health risks, including the potential progression to more severe liver conditions such as liver fibrosis, cirrhosis, and even hepatocellular carcinoma, but its underlying mechanisms are not well understood. This study aimed to identify potential hub genes for NAFLD and evaluate their clinical application in predicting the condition.
Methods: We conducted differential expression analysis and weighted gene co-expression network analysis (WGCNA) to identify NAFLD susceptibility modules and hub genes. We performed KEGG and GO analyses to explore the potential roles of these hub genes. We developed a nomogram model and ROC curves to assess the diagnostic efficacy of the hub genes. Additionally, we investigated the correlation between FOS and immune infiltration. Finally, we conducted a Mendelian randomization study based on genome-wide association studies to determine the causal effect of FOS on NAFLD.
Results: WGCNA analysis was conducted to construct gene co-expression networks, identify the most significant module, and identify 115 key genes derived from the overlapping results of WGCNA and differential expression analysis. GO and KEGG pathway enrichment analyses revealed that these key genes were associated with fat cell differentiation, ameboidal−type cell migration, response to lipopolysaccharide, TNF signaling pathway, MAPK signaling pathway, and AGE−RAGE signaling pathway in diabetic complications. Using Cytoscape software, we identified the top ten up-regulated genes with high scores: FOS, JUN, NR4A1, JUNB, EGR1, MYC, IL1B, CCL2, CXCL8, and PTGS2. Furthermore, our nomogram model demonstrated good performance in predicting NAFLD, and the ROC curve confirmed its diagnostic effectiveness. Finally, we focused on FOS and observed a causal association between FOS and immune cell infiltrates in NAFLD. In the inverse variance weighting analysis, we found that FOS was not associated with the risk of NAFLD, with an odds ratio of 0.997 (95% CI = 0.947-1.049, p = 0.898).
Conclusion: We identified hub genes related to NAFLD, which may provide insights into early diagnostic approaches and contribute to the understanding of molecular mechanisms underlying NAFLD risk genes.
Percutaneous Closure of Patent Ductus Arteriosus with Amplatzer Piccolo Occluder device in infants &lt;2 kg
Authors: Ece İbrahim , Kavurt Ahmet Vedat , Bağrul Denizhan , Dinçel Gökçe Kaya , Torun Gülşah , Çıplak Gökçe , Koca Serhat , Kurt Abdullah , Gül Ayşe esin Kibar , Çetin İbrahim İlker 
Published: October 2023

Abstract
We present our experience of transcatheter patent ductus arteriosus (PDA) closure with AmplatzerTM Piccolo Occluder in infants weighing less than 2 kg.
The data of 19 infants <2 kg who underwent transcatheter PDA closure (TCPC) between December 2019 and October 2022 were evaluated retrospectively. The transvenous antegrade approach was performed in 15 patients, guided by fluoroscopy, venous angiography, and transthoracic echocardiography (TTE) with the placement of the entire device within an intraductal position. The retrograde approach via the femoral artery was performed in 4 patients.
Transcatheter closure was attempted in 19 babies with a median gestational age of 27 weeks {interquartile range (IQR) 25-28 weeks}, median birth weight 905 g (IQR 770-1180 g) and was successfully performed in 16 (84%). The median procedural age was 28 days (IQR 36-47 days), and the median procedural weight was 1480 g (IQR 1155-1800 g). The median procedure and fluoroscopic time were 35 min (IQR 30-60 min) and 12 min (IQR 7-19 min) respectively. After the unsuccessful procedure, PDA closed spontaneously in three patients in short-term follow-up. Three procedural complications were device embolization, pericardial effusion/cardiac tamponade, and femoral artery thrombosis.
In our hospital, TCPC was performed with a high degree of success and an acceptable complication rate in infants <2 kg. Based on our initial experience, early and short-term follow-up is encouraging. Even with less invasive different techniques, the retrograde transarterial approach must be avoided. Mechanical stimulation can effectively promote the closure of the PDA after a failed procedural closure.
Effect of lactic acid concentration in microenvironment of cervical cancer on PD-L1 on the surface of cervical cancer cell in fractionated radiotherapy
Authors: Li Zilin , Chen Xi , Liang Xiaoliang , Li Fang , Liu Hong 
Published: October 2023

Abstract
Objective To explore the correlation between lactic acid level and PD-L1 expression of cervical cancer cells in the microenvironment, and to analyze the impact of radiotherapy on PD-L1 expression of cervical cancer cells.Methods The study is divided into two parts. Firstly, the radiotherapy-resistant Siha cell line was established by the method of multiple fractionation irradiation, and compared to the survival rate with the ordinary medium and the cells in the medium with different concentration of lactic acid following high dose irradiation. The Siha cells were cultured in ordinary medium and medium containing different concentrations of lactic acid, and the expression of PD-L1 was identified by Western blot after the cells were irradiated with small doses of multiple fractions. Secondly, 50 clinical samples were selected, the lactic acid concentration was identified by lactic acid kit, and the PD-L1 expression were identified by immunohistochemical before and after radiotherapy of 9Gy and 18Gy.Results The expression of PD-L1 in cervical cancer tissues will change with the increase of the irradiation dose. Results indicated that the incidence of increased PD-L1 in patients with low PD-L1 expression during radiotherapy was considerably higher than that in patients with high PD-L1 expression. In cervical cancer tissue samples, we found that patients with high lactate concentration in cervical cancer tissues were more likely to have distant lymph node metastasis, and higher expression of PD-L1.Conclusions Radiation therapy and Lactic acid in the tumor microenvironment can alter the PD-L1 expression in tumor cells, making them more resistant to radiotherapy. For patients with locally advanced, metastasis or recurrent cervical cancer, our research hints that the immune checkpoint inhibitors should be administrated at the early stage of radiotherapy for this combination treatment regimen.
The Effect of Hopelessness and Its Improvisation Through Skill Acquisition Among Gap Year Students
Authors: Shahzad Ruhaba 
Published: October 2023

Abstract
The present study aimed to explore the factors behind the level of hopelessness among students in Pakistan. It was hypothesized that skill acquisition affects the level of hopelessness among students going through an academic gap year. The participants of this study comprised 300 (m = 44, f = 256) aged 15–30 years from Karachi, Pakistan. They were approached through a purposive convenient sampling technique. Adult Hope Scale was assessed on the participants to assess their level of hopelessness where the duration of gap years, type of gap years, number of skills, and type of skills were noticed through the demographic form. The statistical analysis showed a significant interaction effect between skill acquisition and hopelessness of the students going through gap year(s). Therefore, the results of the study put forth skill acquisition as the positive factor that can be used to reduce the level of hopelessness among gap year students.
Springing up like mushrooms: established populations of invasive red swamp crayfish in Slovakia
Authors: Lipták Boris , Prati Sebastian , Oficialdegui Francisco J. , Apfelová Mária , Pekárová Stanislava , Kautman Ján , Janský Vladimír , Kouba Antonín 
Published: October 2023

Abstract
The invasive red swamp crayfish Procambarus clarkii is recorded for the first time in Slovakia from two natural localities fed by local thermal springs. The first locality is near Turčianske Teplice in Central Slovakia, just downstream of a commercial culturing facility for aquatic ornamentals, while the other is located approximately 150 km southwards, close to Komárno. Both P. clarkii populations are well-established, with numerous individuals of both sexes, size classes, and ovigerous females. Although none out of 32 screened adult crayfish of both populations tested positive for Aphanomyces astaci, the causative agent of the crayfish plague, its presence cannot be entirely excluded. So far, P. clarkii is confined to small stream stretches in both sites, however, its independent expansion into nearby watercourses can be expected, potentially further facilitated through human translocations. Given the supposedly limited territory conquered, it is strongly advised to implement urgent eradication and control measures. As thermal springs and thermally polluted waters are known hotspots of non-native and potentially invasive species; monitoring of these sites is advised.
Study of thoracic diseases and their relationship to genetics
Authors: Albazna Sara , Almasri Nour , Bardan Housam 
Published: October 2023

Abstract

Background
The importance of the research lies in that it sheds light on an important medical issue, which is the relationship between lung diseases and heredity. It is a new renaissance in the world of medicine that takes us to search for the genetic origin of lung diseases so that we can combat them and modify their patterns before they occur in the first place.
Materials and methods
A cohort study was conducted in Damascus Hospital in the Syrian Arab Republic in the city of Damascus from April 2023 to September 2023.
Results
The study included 100 individuals on whom research and statistics were conducted. Four chest diseases were investigated (asthma - chronic obstructive pulmonary disease - bronchiectasis - idiopathic pulmonary fibrosis). The aim was to shed light on the genetic relationship with these diseases and understand their mechanisms in detail in order to reach an era. New treatment and prevention of its occurrence. The percentage of males in our sample was 57%, and with regard to age, the dominant group was 51–70 years, representing 40%, and the average was 56 years. When asked about habits, the percentage of smokers was 68% of the total sample. Then we looked for chest symptoms, and the most common symptom was shortness of breath at a rate of 98%, followed by coughing at 72%, phlegm at 56%, and finally temperature. When examining chest diseases, asthma was dominant in 56% of the total sample Followed by bronchiectasis at a rate of 27%, then idiopathic pulmonary fibrosis at 9%, and finally chronic obstructive pulmonary disease at 8%. Then we asked about the severity of the infection, with moderate being the dominant factor at 44%, then mild at 33%, and finally severe at 23%.
Conclusion
Genetics is one of the very important sciences in the world of medicine and treatment and one of the least discovered sciences so far. Therefore, shedding light on it in the field of chest diseases and decoding it will reveal to us many means and methods for prevention and treatment at the same time
Urtica Dioica Leaf Extract Attenuates Oxidative Stress Induced by Environment Pollutant Benzo[a] Pyrene in Mouse Testicular Tissues
Authors: Albogami Sarah 
Published: October 2023

Background:
Epidemiological studies have shown that elevated levels of air pollutants are associated with various adverse health effects, including infertility.

Objective:
We aimed to assess the protective effects of aqueous Urtica dioica leaf extract against benzo[a]pyrene -induced oxidative damage in mouse testis.

Methods:
Mice exposed to benzo[a]pyrene were treated with or without aqueous Urtica dioica extract for five weeks, and changes in body and testes weights, messenger RNA levels and activities of antioxidant enzymes, plasma testosterone levels, sperm characteristics, and testicular tissue histology were determined.

Results:
Exposure to benzo[a]pyrene remarkably reduced testis and body weights, the expression and activity of antioxidant enzymes, increased lipid peroxidation, decreased plasma testosterone levels and sperm count and motility, affected sperm morphology and viability, and damaged the seminiferous tubules. Treatment with aqueous Urtica dioica leaf extract attenuated benzo[a]pyrene -induced oxidative stress in the testicular tissue by increasing the expression of antioxidant genes. Further, Urtica dioica leaf extract reduced lipid peroxidation, increased antioxidative enzyme activity, enhanced sperm characteristics, increased plasma testosterone levels, and improved the morphology of the seminiferous tubules.

Conclusion:
Aqueous Urtica dioica leaf extract protects testicular tissue from benzo[a]pyrene -induced oxidative damage and could potentially reverse benzo[a]pyrene -induced infertility.
Cuspal Deflection and Marginal Integrity of Class II Cavities Restored with Bulk-fill Resin Composites
Authors: Duarte Renata Webster , Somacal Deise Caren , Braga Lauanda Rodrigues , Borges Gilberto Antonio , Spohr Ana Maria 
Published: October 2023

Objective:
This laboratory study aims to assess the cuspal deflection, adaptation, and marginal sealing of premolars restored with bulk-fill resin composites.

Methods:
Fourty-four premolars received class II preparations (distal and mesial boxes located 1 mm above and 1 mm below the cementoenamel junction, respectively). The teeth were distributed into four groups according to the resin composite used for restoration (n=11): G1 (control): Filtek Z250 XT; G2: Filtek Bulk-Fill; G3: Tetric N-Ceram Bulk-Fill; G4: Aura Bulk-Fill. A digital micrometer was used to measure the cuspal deflection before and after the restorative procedures. Replicas in epoxy resin of the restored teeth were achieved before and after thermal cycles. The cervical margins were observed by SEM at 200x magnification to obtain the percentage of continuous margins (%CM). After thermal cycles, the samples were immersed in a silver nitrate solution, and the microleakage was analyzed in the cervical margins.

Results:
ANOVA showed no significant differences in the cuspal deflection and %CM among the resin composites. Student’s t-test showed a significant decrease in the %CM after thermal cycles for all resin composites at the cervical margin in dentin. There was higher microleakage at the dentin margin for all the resin composites.

Conclusion:
Bulk-fill resin composites had comparable behavior to conventional composites in regard to the cuspal deflection, adaptation, and marginal sealing parameters.