bluuebunny/crossref_metadata_2025_split huggingface dataset:
How Do First-Year Engineering Students’ Emotions Change while Working on Programming Problems?
Authors: Atiq Zahra , Batra Rakhi 
Published: February 2024

Emotions are a complex multi-faceted phenomenon. To assess the complexity of emotions from different facets, multi-modal approaches are necessary. However, multi-modal approaches are rarely used for assessing emotions, especially in the context of computer programming. This study adopts a multi-modal approach to understand the changes in students’ perception of emotions before and after working on programming problems. Understanding these changes in students’ perceptions may enable educators to devise interventions that help students adjust their perceptions and regulate their emotions as per their skills. We conducted a one-on-one programming session and retrospective think-aloud interview with 17 students from an introductory programming course. During the programming session, students filled surveys and performed four programming tasks. While working on these tasks, students’ eye gaze, video of face and screen, and electrodermal activity data were also collected using a non-invasive device. The data collection for this study was multi-modal, with a mix of both qualitative and quantitative data collection methods. Data analysis was primarily qualitative, with additional triangulation of qualitative and biometric data for select exemplars. The findings of this study suggest that students experience changes in emotions because of many reasons, for instance, they encountered repeated errors, they set high standards for their performance, or they could not manage time. For some students, negative emotions changed to positive emotions when they solved errors without any external help or achieved more than what they expected going into the task. Moreover, the triangulation of qualitative and biometric data of two participants provides a fine-grained analysis of their emotions and behaviors and confirmed the change in the perception of their emotions while performing the programming tasks.
Altered Oxidative Phosphorylation Confers Vulnerability on IDH1-Mutant Leukemia Cells: Is This Therapeutically Tractable?
Authors: Steensma David P. 
Published: February 2024

Summary:
Isocitrate dehydrogenase (IDH)–mutant acute myeloid leukemia (AML) is treatable with inhibitors of mutant IDH and also responds well to combination therapies including venetoclax, but most patients with IDH-mutant AML either never achieve complete remission or relapse because mutant hematopoietic stem cells persist despite treatment. An interesting new study in Blood Cancer Discovery characterizes a specific vulnerability in the mitochondrial oxidative phosphorylation system in preleukemic hematopoietic stem cells from patients with IDH1 mutations that is not present in those with IDH2 mutations; will this susceptibility prove amenable to therapy?
See related article by Landberg et al., p. 114 (10).
“I Don’t Feel Judged. I Just Feel Love”: Perceptions of Animals as Support for Grievers
Authors: Cacciatore Joanne , Gorman Richard , Thieleman Kara , Sullivan Mariah 
Published: February 2024

Abstract
This study explored the ways in which nonhuman animals were perceived to provide social support for grievers. A content analysis was conducted and four key qualities of nonhuman companion animals were identified: 1) presence, 2) continuity and purpose, 3) mutuality and connection, and 4) nature of response. Results suggest that people perceive animals to play an important role in providing emotional support through their presence and tactile experiences, to enhance a sense of purpose after loss, and perceived nonjudgmental acceptance of the griever is highly valued. Additionally, some respondents may feel closer to their loved one through contact with animals associated with them. The type of support perceived from animals overlaps in some ways with human support yet is unique in many ways. Animal support may be especially important for grieving people during pandemic isolation and in the absence of strong social networks.
Consumer Considerations of Carbon Paw Prints in Evaluations of Dog Food Products
Authors: van Prooijen Anne-Marie , Smeets Anne E. M. J. , Yang Kelly X. , Hoppezak Priscilla 
Published: February 2024

Abstract
Due to its reliance on meat, the companion animals’ food industry significantly contributes to environmental problems. Despite these environmental implications, little is known about the relative importance that caregivers attach to environmental concerns in their evaluation of companion animals’ food products. Study 1 (N = 317) showed that perceived nutritional value predicted whether caregivers were interested in plant-based dog food products, while pro-environmental identification did not impact the findings. In Studies 2 (N = 460) and 3 (N = 194), the promoted benefits of a fictitious dog food product were manipulated. Findings revealed that perceived health benefits rather than perceived environmental benefits were the main determinant of product interest. Together, these findings suggest that environmental concerns play a limited role in people’s views of companion animals’ food products. It is therefore important to address concerns about the health impacts of companion animals’ food products with plant-based content.
Mating sub-behaviours in Bursaphelenchus xylophilus on agar and evidence for female cooperation
Authors: Doi Kentaro , Shinya Ryoji 
Published: February 2024

Summary
The pine wood nematode, Bursaphelenchus xylophilus, is the cause of pine wilt disease and reproduces by copulation within host pine trees. Female mate selection in B. xylophilus mating behaviour has been reported but definitive evidence is lacking. Furthermore, while the mating behaviour of the free-living nematode Caenorhabditis elegans on agar has been well understood, the mating behaviour of B. xylophilus on agar has not been studied in detail, and the differences in their characteristics remain unclear. Here, we addressed these knowledge gaps by observing B. xylophilus mating behaviour on agar. We identified six primary mating sub-behaviours in B. xylophilus males. Comparative analysis with C. elegans revealed distinct differences in the sequence of mating stages. Notably, B. xylophilus males actively searched for the female’s vulva during the wrapping stage, whereas females exhibited back-and-forth locomotion to align the male spicule with the vulva location. Additionally, we conducted mating assays using anaesthetised female nematodes to evaluate the female’s role in the mating behaviours of B. xylophilus. The mating duration increased significantly when females were anaesthetised, and the probabilities of reaching the wrapping and vulva location stages were reduced. Therefore, B. xylophilus females actively cooperate in mating behaviours. Our findings highlight unique aspects of mating behaviours in B. xylophilus and provide insights concerning differences in mating behaviours between B. xylophilus and C. elegans.
Monitoring Erosion of a Submerged Stone Age Site and Its Implications for Managing Underwater Cultural Heritage. A Case Study at Tybrind Vig, Denmark
Authors: Bohr Sigurd Arve Baslund , Uldum Otto , Gregory David 
Published: February 2024

Abstract
Known locations with submerged and well-preserved Stone Age sites in Denmark are, in most cases, under constant threat of erosion. The results presented here have been gathered at Tybrind Vig by surveying a 165 m-long transect at 5-metre intervals from the shore, by measurements taken with a total station. To supplement this, the surrounding area was surveyed with an echo sounder/sonar unit that yielded 3D coordinates post-processed in GIS to investigate volumetric changes in the seabed over time. The transect data was used to calibrate the elevation data from the echo sounder, following the correction of sea level change with data gathered from the Danish Coastal Authority. It was established that sediment transport – both erosion and accumulation – has occurred, but from the methods used, it cannot be determined how much of the archaeologically rich gyttja layers have been eroded at Tybrind Vig.
Storytelling about Shipwrecks and Scuttled Ships from the 17–19th Century in the UNESCO World Heritage Site ‘Naval Port of Karlskrona’ in Sweden
Authors: Stråkendal Petra 
Published: February 2024

Abstract
Shipwrecks obviously have stories to tell. Combined with a UNESCO World Heritage site and its Outstanding Universal Value, storytelling becomes a powerful tool for discussions about the preservation, usage, and development of cultural heritages. Within or near the World Heritage the Naval Port of Karlskrona, there is a large number of wrecks and scuttled ships (deliberately sunken ships). The article aims to share examples of how mainly scuttled ships can be used to arouse interest and how their stories can be displayed with different methods. For a long time, scuttled ships have been dismissed with arguments that there are no artefacts left and therefore of less archaeological value. In the Naval Port of Karlskrona, these ships have instead been shown to have an important role in understanding and strengthening the Outstanding Universal Value.
Machine Learning–Based Lightning Parameterizations for the CONUS
Authors: Cheng Wei-Yi , Kim Daehyun , Henderson Scott , Ham Yoo-Geun , Kim Jeong-Hwan , Holzworth Rober H. 
Published: February 2024

Abstract
The diversity in the lightning parameterizations for numerical weather and climate models causes considerable uncertainty in lightning prediction. In this study, we take a data-driven approach to address the lightning parameterization problem, by combining machine learning (ML) techniques with the rich lightning observations from the World Wide Lightning Location Network. Three ML algorithms are trained over the contiguous United States (CONUS) to predict lightning stroke density in a 1° box based on the information about the atmospheric variables in the same grid (local) or over the entire CONUS (nonlocal). The performance of the ML-based lightning schemes is examined and compared with that of a simple, conventional lightning parameterization scheme of Romps et al. We find that all ML-based lightning schemes exhibit a performance that is superior to that of the conventional scheme in the regions and in the seasons with climatologically higher lightning stroke density. To the west of the Rocky Mountains, the nonlocal ML lightning scheme achieves the best overall performance, with lightning stroke density predictions being 70% more accurate than the conventional scheme. Our results suggest that the ML-based approaches have the potential to improve the representation of lightning and other types of extreme weather events in the weather and climate models.
An Unexpected Decline in Spring Atmospheric Humidity in the Interior Southwestern United States and Implications for Forest Fires
Authors: Jacobson Tess W. P. , Seager Richard , Williams A. Park , Simpson Isla R. , McKinnon Karen A. , Liu Haibo 
Published: February 2024

Abstract
On seasonal time scales, vapor pressure deficit (VPD) is a known predictor of burned area in the southwestern United States (“the Southwest”). VPD increases with atmospheric warming due to the exponential relationship between temperature and saturation vapor pressure. Another control on VPD is specific humidity, such that increases in specific humidity can counteract temperature-driven increases in VPD. Unexpectedly, despite the increased capacity of a warmer atmosphere to hold water vapor, near-surface specific humidity decreased from 1970 to 2019 in much of the Southwest, particularly in spring, summer, and fall. Here, we identify declining near-surface humidity from 1970 to 2019 in the southwestern United States with both reanalysis and in situ station data. Focusing on the interior Southwest in the months preceding the summer forest fire season, we explain the decline in terms of changes in atmospheric circulation and moisture fluxes between the surface and the atmosphere. We find that an early spring decline in precipitation in the interior region induced a decline in soil moisture and evapotranspiration, drying the lower troposphere in summer. This prior season precipitation decline is in turn related to a trend toward a Northern Hemisphere stationary wave pattern. Finally, using fixed humidity scenarios and the observed exponential relationship between VPD and burned forest area, we estimate that with no increase in temperature at all, the humidity decline alone would still lead to nearly one-quarter of the observed VPD-induced increase in burned area over 1984–2019.

Significance Statement
Burned forest area has increased significantly in the southwestern United States in recent decades, driven in part by an increase in atmospheric aridity [vapor pressure deficit (VPD)]. Increases in VPD can be caused by a combination of increasing temperature and decreasing specific humidity. As the atmosphere warms with climate change, its capacity to hold moisture increases. Despite this, there is a decrease in near-surface air humidity in the interior southwestern United States over 1970–2019, which during the summer is likely caused by a decline in early spring precipitation leading to limited soil moisture and evaporation in spring and summer. We estimate that this declining humidity alone, without an increase in temperature, would cause about one-quarter of the VPD-induced increase in burned forest area in this region over 1984–2019.
The Delphi of ORACLE: An Expert Consensus Survey for the Development of the Observational Risk Assessment of Contractures (Longitudinal Evaluation)
Authors: Tariq Hina , Collins Kathryn , Dunn Joel , Tait Desiree , Porter Sam 
Published: February 2024

Objective Despite rising prevalence rates, no standard tool is available to identify individuals at risk of developing contractures. This study aimed to gain expert consensus on items for the development of the Observational Risk Assessment Tool for Contractures: Longitudinal Evaluation (ORACLE) for care home residents. Design A two-round, online modified Delphi study. Participants Panellists were qualified healthcare professionals with a background in physiotherapy, occupational therapy, nursing, and rehabilitation medicine. Main outcome measures In the first round, the experts were asked to rate the predesigned list of items on a Likert scale while in the second round, consensus was sought in the areas of disagreement identified in the previous round. Results The two rounds of the Delphi survey included 30 and 25 panellists, respectively. The average clinical and academic experience of the panellists was 22.2 years and 10.5 years, respectively. The panel demonstrated a high level of consensus regarding the clinical factors (10 out of 15 items); preventive care approaches (9 out of 10 items), and contextual factors (12 out of 13 items) ranging from 70% to 100%. Conclusion This Delphi study determined expert consensus on items to be included in a contracture risk assessment tool (ORACLE). The items were related to factors associated with joint contractures, appropriate preventive care interventions, and potentially relevant contextual factors associated with care home settings. The promise of a risk assessment tool that includes these items has the capacity to reduce the risk of contracture development or progression and to trigger timely and appropriate referrals to help prevent further loss of function and independence.
A semi-naturalistic open-label study examining the effect of prescribed medical cannabis use on simulated driving performance
Authors: Manning Brooke , Arkell Thomas R , Hayley Amie C , Downey Luke A 
Published: February 2024

Background: Despite increasing medical cannabis use, research has yet to establish whether and to what extent products containing delta-9-tetrahydrocannabinol (THC) impact driving performance among patients. Stable doses of prescribed cannabinoid products during long-term treatment may alleviate clinical symptoms affecting cognitive and psychomotor performance. Aim: To examine the effects of open-label prescribed medical cannabis use on simulated driving performance among patients. Methods: In a semi-naturalistic laboratory study, 40 adults (55% male) aged between 23 and 80 years, consumed their own prescribed medical cannabis product. Driving performance outcomes including standard deviation of lateral position (SDLP), the standard deviation of speed (SDS), mean speed and steering variability were evaluated using the Forum8 driving simulator at baseline (pre-dosing), 2.5 h and 5 -h (post-dosing). Perceived driving effort (PDE) was self-reported after each drive. Oral fluid and whole blood samples were collected at multiple timepoints and analysed for THC via liquid chromatography-mass spectrometry. Results: A significant main effect of time was observed for mean speed (p = 0.014) and PDE (p = 0.020), with patients displaying modest stabilisation of vehicle control, increased adherence to speed limits and reductions in PDE post-dosing, relative to baseline. SDLP (p = 0.015) and PDE (p = 0.043) were elevated for those who consumed oil relative to flower-based products. Detectable THC concentrations were observed in oral fluid at 6-h post-dosing (range = 0–24 ng/mL). Conclusions: This semi-naturalistic study suggests that the consumption of medical cannabis containing THC (1.13–39.18 mg/dose) has a negligible impact on driving performance when used as prescribed.
Mifepristone decreases nicotine intake in dependent and non-dependent adult rats
Authors: Chellian Ranjithkumar , Behnood-Rod Azin , Bruijnzeel Adriaan W 
Published: February 2024

Background: Addiction to tobacco and nicotine products has adverse health effects and afflicts more than a billion people worldwide. Therefore, there is an urgent need for new treatments to reduce tobacco and nicotine use. Glucocorticoid receptor blockade shows promise as a novel treatment for drug abuse and stress-related disorders. Aim: These studies aim to investigate whether glucocorticoid receptor blockade with mifepristone diminishes the reinforcing properties of nicotine in rats with intermittent or daily long access to nicotine. Methods: The rats self-administered 0.06 mg/kg/inf of nicotine for 6 h per day, with either intermittent or daily access for 4 weeks before treatment with mifepristone. Daily nicotine self-administration models regular smoking, while intermittent nicotine self-administration models occasional smoking. To determine whether the rats were dependent, they were treated with the nicotinic acetylcholine receptor antagonist mecamylamine, and somatic signs were recorded. Results: The rats with intermittent access to nicotine had a higher level of nicotine intake per session than those with daily access but only the rats with daily access to nicotine showed signs of physical dependence. Furthermore, mecamylamine increased nicotine intake during the first hour of access in rats with daily access but not in those with intermittent access. Mifepristone decreased total nicotine intake in rats with intermittent and daily access to nicotine. Moreover, mifepristone decreased the distance traveled and rearing in the open field test and operant responding for food pellets. Conclusion: These findings indicate that mifepristone decreases nicotine intake but this effect may be partially attributed to the sedative effects of mifepristone.
Primary Hip Arthroscopy in Patients With Acetabular Dysplasia: A Systematic Review of Published Clinical Outcomes at Minimum 5-Year Follow-up
Authors: Boos Alexander M. , Nagelli Christopher V. , Okoroha Kelechi R. , Sierra Rafael J. , Krych Aaron J. , Hevesi Mario 
Published: February 2024

Background: Hip arthroscopy in patients with borderline hip dysplasia has satisfactory outcomes at short-term follow-up; however, the data on midterm outcomes are inconsistent, and failure rates are high in some studies, limiting understanding of the role and utility of hip arthroscopy in this patient cohort. Purpose: To provide an up-to-date, evidence-based review of the clinical outcomes of primary hip arthroscopy in patients with frank or borderline hip dysplasia at ≥5-year follow-up and report the failure rate and progression to total hip arthroplasty in this cohort. Study Design: Systematic review; Level of evidence, 4. Methods: A comprehensive literature search was performed according to the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Studies were included if they evaluated outcomes of primary hip arthroscopy in patients with lateral center-edge angle (LCEA) <25° at ≥5-year follow-up. Risk of bias assessment was performed using the methodological index for non-randomized studies scoring system. Level of evidence was determined using criteria from the Oxford Centre for Evidence-Based Medicine. Results: Nine studies were included in this review. Patients with LCEA <25° demonstrated satisfactory clinical outcomes, high patient satisfaction, and significant postoperative improvements in patient-reported outcomes (PROs) at follow-up ranging from a ≥5 to 10 years. Studies comparing patients with dysplasia to those without did not demonstrate significant differences in preoperative, postoperative, or delta PROs or in failure, reoperation, or revision rates. There was no overall significant correlation between outcomes and LCEA stratification. Conclusion: Hip arthroscopy in carefully selected patients with LCEA <25° can be successful at mid- to long-term follow-up and may provide clinical outcomes and failure rates comparable with patients with normal LCEA, understanding that this is a singular, 2-dimensional radiographic measure that does not differentiate instability from impingement or combinations thereof, warranting future studies delineating these differences. These findings suggest that hip dysplasia may not be an absolute contraindication for isolated hip arthroscopy and may serve as a viable intervention with consideration of staged future periacetabular osteotomy (PAO). Importantly, this review does not suggest that hip arthroscopy alters the natural history of dysplasia; therefore, patients with dysplasia should be counseled on the potential utility of PAO by appropriate hip preservation specialists.
Local Health Service Response to COVID-19 in Mexico: Notes From an Exploratory Qualitative Study
Authors: Gutiérrez-Alba Gaudencio , Muños Hernández José Alberto , Juárez-Ramírez Clara , Reartes-Peñafiel Diana L. , Reyes-Morales Hortensia 
Published: February 2024

Background The main goal of a health system is to maintain or improve people’s health. The COVID-19 pandemic showed the fragility of health systems worldwide. In Mexico, the pandemic affected the performance of the health system, along with the presence of contextual conditions such as its segmentation and high prevalence of chronic diseases. Aims To analyze from an approach to the functions of the health system, the service delivery, human resources, financing, and stewardship/governance in the local health services of five states of Mexico, from the perspective of the staff working in health centers. Methods This is an exploratory qualitative study conducted from November 2020 to August 2021, involving 124 health professionals from 39 health facilities (18 rural and 21 urban). The technique used was the semi-structured interview. Interview guides were developed according to core topics. Subsequently, the thematic analysis method was used. Results The lack of financial resources delayed prevention efforts and made it difficult for health centers to adapt to the crisis. Inequity was found in the distributive efficiency of staff between rural and urban areas and levels of care. In addition, there was evidence of capacity for coordination, capacity sharing, and joint participation between health institutions, civil authorities, and the population to face the emergency. Conclusions We identified relevant public health actions that showed the capacity of local health services to organize a response to the pandemic at the level of the actors responsible for these services.