bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social support among English learners with disabilities and other adolescents
Authors: Pham Yen K. , Murray Christopher , Wang Qing , Bromley Katherine W. , Knowles Christen , Sinclair James , Petcu Stefania , Coleman Erin 
Published: January 2024

AbstractIntroductionSocial support is important for many youth but may be particularly important for English learners (ELs) with disabilities, a population that has historically faced barriers accessing resources to meet their educational needs. The current study investigates social support from parents, peers, teachers, and schools in a nationally representative sample of adolescents.MethodData from the National Longitudinal Transition Study 2012 was used to evaluate potential group differences in social support among participants that included ELs with (n = 440) and without disabilities (n = 100) and non‐ELs with (n = 4890) and without disabilities (n = 1090). A multivariate analysis of covariance was conducted to evaluate potential between‐group variations in social support among these student groups after controlling for variations in background demographic characteristics.Results and ConclusionsResults showed between group differences in parental support and peer connectedness but not in teacher or school support. Parents of students with disabilities reported the highest levels of support, whereas parents of ELs without disabilities reported the lowest levels of support. Students with disabilities reported the lowest levels of peer connectedness among the four groups. Overall, levels of teacher and school supports were high across all four groups of students. These patterns contribute to our understanding of the social support network of ELs with disabilities in comparison to other students. Further investigation is needed to examine the mechanisms that contribute to these differences.
Seeing is believing: The effect of subtle communication in social media on viewers' beliefs about depression and anxiety symptom trajectories
Authors: Whitted Whitney M. , Southward Matthew W. , Howard Kristen P. , Wick Samantha B. , Strunk Daniel R. , Cheavens Jennifer S. 
Published: January 2024

AbstractObjectiveOne barrier to treatment seeking, uptake, and engagement is the belief that nothing can be done to reduce symptoms. Given the widespread use of social media to disseminate information about important issues, including psychological health, we sought to understand how the influence of social media communication regarding mental health impacts viewers' beliefs about psychopathology recovery.MethodUndergraduate participants from a large Midwestern university (N = 322) were randomized to view a series of Tweets characterizing psychopathology from a fixed mindset perspective, a growth mindset perspective, or, in the control condition, Tweets unrelated to psychopathology. Afterward, they completed a series of questionnaires designed to assess beliefs about recovery from depression and anxiety.ResultsParticipants in the growth mindset condition endorsed less pessimistic beliefs about their ability (i.e., self‐efficacy) to alleviate symptoms of depression and anxiety, and they believed these symptoms to be less stable and innate relative to those in the fixed mindset condition.ConclusionSocial media communication that characterizes psychopathology from a growth mindset perspective may be a viable intervention for improving beliefs around mental health self‐efficacy and the malleable nature of mental illness, particularly depression and anxiety. Clinicians may be able to use social media platforms to promote functional beliefs around mental illness.
Uncovering an undisclosed diagnosis: a glucose‐6‐phosphate dehydrogenase deficiency diagnosis in a critically ill adult
Authors: Kasturiarachi Brittany M. , Robinson David , Karkoska Kristine , Gollamudi Jahnavi 
Published: January 2024

AbstractGlucose‐6‐phosphate dehydrogenase (G6PD) deficiency affects over 400 million people worldwide. The most common variant of G6PD deficiency in the United States is the A‐variant, which is present amongst African‐Americans. Most people with this variant, however, do not experience severe hemolysis unless under extreme circumstances. Here, we present the case of a 44‐year‐old African‐American male who under circumstances of multiple admissions for critical illness eventually presented with a masked diagnosis of G6PD deficiency.
Vendor selection in the wake of data breaches: A longitudinal study
Authors: Wang Qian , Jiang Shenyang , Ngai Eric W. T. , Huo Baofeng 
Published: January 2024

AbstractWith the increasing digitization and networking of medical data and personal health information, information security has become a critical factor in vendor selection. However, limited understanding exists regarding how information security influences vendor selection. Drawing from the attention‐based view (ABV), this study examines the potential impact of data breaches on hospitals' selection of electronic medical record system (EMRS) vendors. To test our hypotheses, we compile a unique dataset spanning 12 years of observations from US hospitals. Utilizing a coarsened exact matching (CEM) technique combined with a difference‐in‐differences (DiD) approach, our study shows that hospitals tend to replace their EMRS vendors after experiencing data breaches. Moreover, breached hospitals tend to prioritize information security in such a vendor replacement process by switching to star vendors and migrating towards a single‐sourcing configuration. Further post‐hoc analyses reveal that these impacts of data breaches are mitigated as the relationship between breached hospitals and vendors matures or when hospitals belong to large healthcare systems. Additionally, we find that the effects of data breaches are contingent on the scale of the breach and are short‐term in nature. This research underscores the significance of information security as a crucial consideration in vendor selection for both academia and practitioners.
Effect of amniotic membrane/collagen scaffolds on laryngeal cartilage repair
Authors: Iravani Kamyar , Mousavi Simin , Owji Seyed Mohammad , Sani Mahsa , Owji Seyed Hossein 
Published: January 2024

AbstractObjectivesLaryngeal cartilage defects are a major problem that greatly impacts structural integrity and function. Cartilage repair is also a challenging issue. This study evaluated the efficacy of a collagen scaffold enveloped by amniotic membrane (AM/C) on laryngeal cartilage repair.Study DesignExperimental animal study.MethodsFourteen Dutch rabbits were enrolled in the study. A 5 mm cartilage defect was created in the right and left thyroid lamina. The animals were divided into two groups randomly. Group 1 collagen scaffolds and group 2 AM/C were applied to the right side defects. Left side defects were not repaired, serving as control. Histologic evaluation was done 45 and 90 days following collagen and AM/C application with criteria of tissue and cell morphology, lacuna formation, vascularization, and inflammation.ResultsSignificant improvement in cartilage repair was observed in the AM/C side compared to the control side in all histologic criteria after 45 days (p<.05). After 90 days, cartilage repair improved in cell morphology, lacuna formation, and inflammation significantly (p<.05).ConclusionThe combination of amniotic membrane and collagen scaffolds provides a promising treatment modality for improving the repair of laryngeal cartilage defects.Level of EvidenceNA.
Role of dietary intake of specific polyunsaturated fatty acids (PUFAs) on colorectal cancer risk in Iran
Authors: Seyyedsalehi Monireh Sadat , Hadji Maryam , Collatuzzo Giulia , Rashidian Hamideh , Sasanfar Bahareh , Huybrechts Inge , Chajes Veronique , Boffetta Paolo , Zendehdel Kazem 
Published: January 2024

AbstractHigh‐fat diets have been associated with colorectal cancer (CRC) risk, and the role of polyunsaturated fatty acids (PUFAs) has been reported to vary based on the length of PUFAs. We explored the association between dietary omega‐6 and omega‐3 PUFAs intake and CRC. We analyzed 865 CRC patients and 3206 controls from a case–control study of Iran (IROPICAN study). We used multivariate logistic regression models to calculate the odds ratios (OR) and 95% confidence intervals (CI) for the association between PUFAs intake and CRC risk. Our results showed that gamma‐linolenic acid (18:3 n‐6, GLA), arachidonic acid (20:4n‐6, ARA), a‐linolenic acid (Cis‐18:3n‐3, ALA), eicosapentaenoic acid (20:5n‐3, EPA), docosahexaenoic acid (22:6n‐3, DHA) consumption was not associated with the risk of CRC. However, the OR of linoleic acid (18: 2n‐6, LA) intake was 1.47 (95% CI 1.01–2.14, p = 0.04) for proximal colon and that of docosapentaenoic acid (22:5n‐3, DPA) intake was 1.33 (95% CI 1.05–1.69, p = 0.01) for rectum. This study indicates a high level of LA is associated with an increased risk of proximal colon cancer, and DPA intake was positively associated with rectum cancer risk. Furthermore, our study noted a high intake of n‐6 (from vegetable oils) compared to n‐3 PUFAs (from fish and seafood) in this population. Public awareness and government support is needed to increase fish and seafood production and consumption in Iran.
Liensinine inhibits progression of intrahepatic cholangiocarcinoma by regulating TGF‐β1 /P‐smad3 signaling through HIF‐1a
Authors: Zhu Xuewen , Bao Wenming , Xie Xiaozai , Chen Bo , Li Rizhao , Zhao Jungang , Wu Lijun , Yu Zhengping , Li Shi , Zhu Qiandong , Chen Gang , Li Jiacheng 
Published: January 2024

AbstractIntrahepatic cholangiocarcinoma (ICC) is a high‐grade malignant digestive system tumor with an insidious onset and unfavorable prognosis. Liensinine, a small molecule derived from plants, has been proven to have significant tumor suppressor activity in other cancers. However, there are no reports on whether liensinine can inhibit the proliferation or metastasis of ICC. This study aimed to explore the tumor‐suppressive activity of liensinine in ICC and its underlying mechanisms. The phenotypic changes in ICC cells were monitored in vitro using cell function tests. Western blot and immunofluorescence analyses verified the efficacy of liensinine. Tumor‐bearing nude mice were used to explore the effect of liensinine on tumors and its toxicity and side effects in vivo. Liensinine suppressed ICC cell proliferation and arrested the cell cycle at the G1 phase. The epithelial‐mesenchymal transition (EMT) of ICC cells was also inhibited, thereby restraining their invasion and migration of tumor cells. In addition, this study found that the potential mechanism of liensinine inhibiting EMT may be via suppression of the TGF‐β1/P‐smad3 signaling pathway through hypoxia‐inducible factor 1 alpha (HIF‐1a). In vivo experiments showed that liensinine inhibited the growth of Hucc‐T1 transplanted tumors in nude mice. Liensinine restrained the proliferation of ICC cells and suppressed EMT in ICC via the HIF‐1a‐mediated TGF‐β1/P‐smad3 signaling pathway.
Multicomponent gas sensors based on photoacoustic spectroscopy technology: A review
Authors: Sun Jialiang , Liu Bing , Liu Lixian , Huan Huiting , Zhang Le , Zhang Xueshi , Yang Junchao , Shao Xiaopeng 
Published: January 2024

AbstractPhotoacoustic spectroscopy (PAS), with the advantages of high sensitivity, extensive dynamic range, high selectivity, and nondestructive, has become one of the research hotspots in multigas detection. This review aims to discuss the latest advancements in PAS for multicomponent gas detection. The key elements of the PAS technique available to support multigas detection, namely as the optical source, and the recent developments in detection methods are presented. The different optical source‐based experimental systems such as broadband light sources and various lasers are reported, and related multigas modulation methods and the performances are analyzed. Finally, in terms of the characteristics of selectivity, sensitivity, and miniaturization, we discuss the advantages and limitations of these different multicomponent trace gas PAS techniques towards practical application.
What should be next in lifelong posterior hypospadias: Conclusions from the 2023 ERN eUROGEN and EJP‐RD networking meeting
Authors: Lammers Rianne J. M. , Tsachouridis George , Andersson Marie K. , Dormeus Sarah , Ekerhult Teresa O. , Frankiewicz Mikołaj , Gunn Callum J. , Matuszewski Marcin , de Mooij Keetje L. , Schroeder Rogier P. J. , Wyndaele Michel I. A. , Xing Zhentao , De Kort Laetitia M. O. , de Graaf Petra 
Published: January 2024

AbstractBackgroundA congenital disease is for life. Posterior hypospadias, the severe form of hypospadias with a penoscrotal, scrotal, or perineal meatus, is a challenging condition with a major impact on lifelong quality of life.AimOur network meeting is aimed to identify what is currently missing in the lifelong treatment of posterior hypospadias, to improve care, quality of life, and awareness for these patients.MethodsThe network meeting “Lifelong Posterior Hypospadias” in Utrecht, The Netherlands was granted by the European Joint Programme on Rare Diseases–Networking Support Scheme. There was a combination of interactive sessions (hackathons) and lectures. This paper can be regarded as the last phase of the hackathon.ResultsSurgery for hypospadias remains challenging and complications may occur until adulthood. Posterior hypospadias affects sexual function, fertility, and hormonal status. Transitional care from childhood into adulthood is currently insufficiently established. Patients should be more involved in defining desired treatment approach and outcome measures. For optimal outcome evaluation standardization of data collection and registration at European level is necessary. Tissue engineering may provide a solution to the shortage of healthy tissue in posterior hypospadias. For optimal results, cooperation between basic researchers from different centers, as well as involving clinicians and patients is necessary.ConclusionsTo improve outcomes for patients with posterior hypospadias, patient voices should be included and lifelong care by dedicated healthcare professionals guaranteed. Other requirements are joining forces at European level in uniform registration of outcome data and cooperation in basic research.
Exploring lifelong overactive bladder: Transitions, evidence, and clinical implications; A modified Delphi process
Authors: Bou Kheir George , Verbakel Irina , Vande Walle Johan , Wyndaele Michel , Sinha Sanjay , Arlandis Salvador , Raes Ann , Abrams Paul , Wein Alan , Hervé François , Everaert Karel 
Published: January 2024

AbstractIntroductionOveractive bladder (OAB) is a prevalent urological condition characterized by urinary urgency, with or without urgency urinary incontinence, accompanied by increased daytime frequency and nocturia. However, the current definition of OAB lacks a specified time frame, hindering our understanding of the temporal aspects and transitions that occur within the OAB spectrum.MethodsA modified Delphi study was conducted in three rounds, involving a panel of international experts in functional urology, urogynaecology, geriatrics, transitional medicine, and pediatric urology. The study took place between February 2023 and June 2023 and employed two sequential rounds of online surveys, followed by a final hybrid group discussion session in June 2023.ResultsThe Delphi process resulted in a consensus definition of lifelong OAB as a persistent and continuous condition that may manifest differently from birth and evolve over time, with varying levels of clinical perception. The course of its progression is influenced by transition periods and modifying factors, mainly anatomical, hormonal, and psychosocial/stressors. Three main transition periods were identified: achievement of daytime continence, adulthood to elderly, and transition to frail elderly. The panel also considered the therapeutic and diagnostic implications of lifelong OAB, as well as future research prospects in terms of importance and feasibility.ConclusionsFuture longitudinal research is needed to develop this concept and further identify transitions and temporal dynamics.
Selective O‐Acylation of Enol Silyl Ethers with Acyl Fluorides Catalyzed by Fluoride Ions Derived from Potassium Fluoride and 18‐Crown‐6
Authors: Sakai Norio , Watanabe Kota , Mori Haruka , Maegawa Yuki , Takeuchi Ryuki , Ogiwara Yohei , Ishida Kento 
Published: January 2024

AbstractThe fluoride ion‐catalyzed selective O‐acylation of enol silyl ethers with acyl fluorides using KF and 18‐Crown‐6 is described herein. This catalytic system facilitated the practical and facile reaction of a variety of enol silyl ethers derived from aromatic/aliphatic ketones and aldehydes with acyl fluorides to afford useful and valuable enol esters.
Synthesis and performance evaluation of a novel zwitterionic quaternary copolymer for enhanced oil‐recovery application
Authors: Qin Xiaoping , Xie Zhaolin , Tang Peng , Yang Hui , Li Cuixia , Yang Xiaoliang , Peng Tong 
Published: January 2024

AbstractA novel quaternary copolymer of AA/AM/AOS/C16‐DMAAC was synthesized with acrylic acid (AA), acrylamide (AM), sodium α‐alkenyl‐sulfonate (AOS), and dimethyl‐hexadecyl‐allyl‐ammonium chloride (C16‐DMAAC), using ammonium persulfate and sodium bisulfate (NH4)2S2O8‐NaHSO3) as initiators. The structure of AA/AM/AOS/C16‐DMAAC was characterized using Fourier transform infrared spectroscopy and nuclear magnetic resonance hydrogen spectroscopy. It can be found that the thickening capacity, shearing resistance, temperature‐resistance, salt‐resistance, and emulsification properties of AA/AM/AOS/C16‐DMAAC were superior to those of most widely and cost‐effective partially hydrolyzed polyacrylamide (HPAM) solution at the same concentration. Specifically, the viscosity retention rate of AA/AM/AOS/C16‐DMAAC (3000 mg/L) solution was 86%, which was better than that of HPAM solution (52%) after 30 s of mechanical shearing at 28000 r/min. In addition, the enhanced oil recovery of AA/AM/AOS/C16‐DMAAC solution was 16% at 65 °C, which was about 1.5 times higher than that of HPAM solution (11%). Significantly, successful synthesis of zwitterionic quaternary copolymer emphasizes the importance of a systematic approach to designing appropriate copolymers for enhanced oil recovery.HighlightsA novel zwitterionic quaternary copolymer of AA/AM/AOS/C16‐DMAAC was successfully synthesized.The performance on thickening capacity, shearing resistance, temperature‐resistance, salt‐resistance, and emulsification properties of AA/AM/AOS/C16‐DMAAC was superior to that of the most widely used partially hydrolyzed polyacrylamide (HPAM).The enhanced oil recovery of AA/AM/AOS/C16‐DMAAC (16%) was about 1.5 times higher than that of HPAM (11%).
Preferences and perspectives regarding telehealth exercise interventions for adults with cystic fibrosis: A qualitative study
Authors: Poulsen Megan , Holland Anne E. , Button Brenda , Jones Arwel W. 
Published: January 2024

AbstractObjectivePhysical activity and exercise are key components in the management of cystic fibrosis (CF). Completing exercise programs online may minimize the risk of cross‐infection and increase access for people with CF. This study aimed to understand the perspectives of people with CF regarding intervention content for a telehealth exercise program.MethodsIndividual semistructured qualitative interviews were conducted in adults with CF purposefully sampled for age, disease severity, and social demographics. Interviews were recorded, transcribed verbatim, and analyzed thematically by two researchers independently.ResultsParticipants were 23 adults with CF (14 females) aged from 21 to 60 years. Three major themes (subthemes) were generated: “Personalizing components to an exercise program” (customizing an exercise program to the individual person and their unique health and exercise needs, enjoyment and variety of exercise activities, accessibility and exercise fitting around competing demands or commitments), “The importance of maintaining connections” (challenges regarding face‐to‐face interactions for people with CF, accountability of scheduled exercise sessions with others, shared experiences between people with CF and specialist support from the CF care team), and “Monitoring health and exercise” (perception of health status and monitoring and recording exercise participation and health).ConclusionThis study provides important information regarding the preferences of adults with CF for telehealth exercise interventions. Interventions should be tailored to the individual person with CF, include an opportunity to maintain connections with peers and the CF multidisciplinary team, and provide a method to monitor progress over time.
The increase of bronchiolitis severity in the 2022–2023 season in an Italian tertiary children's hospital: An isolated phenomenon or a warning sign?
Authors: Brisca Giacomo , Strati Marina Francesca , Buratti Silvia , Mariani Marcello , Ferretti Marta , Pirlo Daniela , Meleca Vincenzo , Piccotti Emanuela , Castagnola Elio , Moscatelli Andrea 
Published: January 2024

AbstractAimRecent literature has shown epidemiological changes in bronchiolitis with an increased incidence in the post‐SARS‐CoV‐2 pandemic period but reports regarding disease severity are conflicting. We aimed to describe the epidemiology, disease severity, and microbiology of bronchiolitis during the 2022–2023 cold season compared to the previous 5 years.MethodsThis single‐center retrospective observational study at IRCCS Gaslini, Italy, included all children aged 0–2 years hospitalized for bronchiolitis from 1 September 2017 to 31 August 2023. Findings from the 2022–2023 season were compared to the previous 5 years.ResultsWe observed a statistically significant increase in the 2022–2023 season in the absolute number of bronchiolitis admissions. Children who required mechanical ventilation (MV) dramatically increased from a total of seven patients in the previous five seasons to 17 in the 2022–2023 season alone (p = .001). All other severity parameters significantly increased: the need for respiratory support (p = .002), the median length of stay (5 days vs. 4 days, p = .001), and the median duration of respiratory support (4 days vs. 3 days, p = .016).ConclusionsWe report a substantial increase in the severity of bronchiolitis in the season 2022–2023 with a remarkable number of previously healthy infants requiring MV. Further studies are needed to confirm whether our findings are an isolated phenomenon or part of a true global trend. Health systems need to be prepared and protective preventive measures should be implemented for all newborns.