bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electrophysiological and behavioral responses of elongated solifuge sensilla to mechanical stimuli
Authors: Kundu Pallabi , Oviedo-Diego Mariela , Cargnelutti Franco , Jones R. Ryan , Garcia Erika , Hebets Eileen A. , Gaffin Douglas D. 
Published: February 2025

Abstract
A fundamental understanding of animal sensory systems is crucial for comprehending their interactions with the environment and with other conspecifics. However, knowledge gaps persist, particularly in arachnids like the order Solifugae. While certain solifuge setae and palpal papillae have been studied structurally and electrophysiologically, providing evidence of chemoreception and mechanoreception, the sensilla on their walking legs remain unexplored. Notably, elongated sensilla on the femur and tibia of the 4th walking legs resemble trichobothria in other arachnid orders yet their function remains unknown. Thus, this study investigates whether these sensilla serve a mechanosensory function. Using electrophysiological and behavioral assays on Eremobates pallipes (Eremobatidae), we assessed the response of the elongated 4th leg sensilla to– (i) air particle movement and– (ii) air pressure changes. Air particle movement stimuli were generated using a speaker placed in the near field of the elongated sensilla that emitted low-frequency pure tones (10–1000 Hz). Air pressure stimuli involved forceful blowing on the sensilla. No response to air particle movement was observed, but a mechanosensory response to air pressure stimuli was detected. Electrophysiological data identified a fast-adapting and fast-recovering cell, and behavioral observations revealed a startle response. Our electrophysiology results suggest a mechanosensory role of elongated sensilla on the 4th walking legs of solifuge, indicating that although they are not sensitive enough to detect air particle movement stimuli, they can receive and respond to air pressure stimuli. Our behavioral experiments similarly show that these sensilla are not sensitive enough to detect air particle movement but respond to more forceful mechanosensory stimuli.
In renal proximal tubular epithelial cells of the hibernator Syrian hamster, anoxia-reoxygenation-induced reactive oxygen species bursts do not trigger a DNA damage response and cellular senescence
Authors: Pissas Georgios , Divani Maria , Tziastoudi Maria , Poulianiti Christina , Polyzou-Konsta Maria-Anna , Lykotsetas Evangelos , Stefanidis Ioannis , Eleftheriadis Theodoros 
Published: February 2025

Abstract
Ischemia-reperfusion (I-R) injury represents a predominant etiology of acute kidney injury (AKI), for which effective treatments remain unavailable. In contrast, hibernating mammals exhibit notable resistance to cell death induced by I-R injury. However, the impact of I-R injury on cellular senescence—an important factor in AKI—has not been extensively studied in these species. Comparative biology may offer novel therapeutic insights. Renal proximal tubular epithelial cells (RPTECs) from the native hibernator Syrian hamster or mouse RPTECs were subjected to anoxia-reoxygenation. Proteins involved in DNA damage response (DDR) and cellular senescence were assessed using western blotting, reactive oxygen species (ROS) levels and cell death were quantified colorimetrically, and IL-6 with ELISA. Anoxia-reoxygenation induced oxidative stress in both mouse and hamster RPTECs; however, cell death was observed exclusively in mouse cells. While anoxia-reoxygenation elicited a DDR and subsequent senescence in mouse RPTECs, such responses were not detected in hamster RPTECs. Thus, RPTECs from the Syrian hamster exhibited increased ROS production upon reoxygenation but did not show DDR or cellular senescence. Further research is required to elucidate the specific protective molecular mechanisms in hibernators, which could potentially lead to the development of novel therapeutic approaches for I-R injury in non-hibernating species, including humans.
Great ape infants’ face touching and its role in social engagement
Authors: Felicio Beatriz , Bard Kim A. 
Published: February 2025

Abstract
Touch has a key role in the social development of infant primates and in the regulation of social interactions, even so, there’s a rarity of studies on infants’ use of social touch. In this work, we document chimpanzee infants and human infants’ touching of other’s faces, a behavior already described in wild capuchin monkey infants, and investigate possible functions of infants’ social touch. A strength of this study is that we sampled chimpanzee and human infants from three different social ecologies each. Each infant was observed naturalistically, in their everyday environments. In 36 h of observation, we found 269 touch events, specifically 222 face touches and 47 head touches. We found significant differences between groups, within species. Face touching occurred preferentially with adult females in all groups, and preferentially in prosocial contexts, although the most preferred contexts differed across groups. A unifying concept was that almost all infant face touching occurred during joint attention events. We interpret this as the ability of 1-year-olds to use face touching as a behavioral marker of mutual engagement during bouts of triadic connectedness, that is when they engage together with a social partner about an object or an event. In this study, we document an understudied behavior of young chimpanzees and humans, one that is not only part of prosocial interactions, but one that may function to highlight infants’ active role in engagement with another, while they together engage in triadic connectedness.
Surgical treatment for hepatocellular carcinoma in era of multidisciplinary strategies
Authors: Takamoto Takeshi , Mihara Yuichirou , Nishioka Yujirou , Ichida Akihiko , Kawaguchi Yoshikuni , Akamatsu Nobuhisa , Hasegawa Kiyoshi 
Published: February 2025

Abstract
Hepatocellular carcinoma (HCC) remains a significant global health challenge, with over 800,000 new cases diagnosed annually. This comprehensive review examines current surgical approaches and emerging multidisciplinary strategies in HCC treatment. While traditional surgical criteria, such as the Barcelona Clinic Liver Cancer (BCLC) staging system, have been relatively conservative, recent evidence from high-volume Asian centers supports more aggressive surgical approaches in carefully selected patients. The review discusses the evolution of selection criteria, including the new “Borderline Resectable HCC” classification system, which provides more explicit guidance for surgical decision-making. Technical innovations have significantly enhanced surgical precision, including three-dimensional simulation, intraoperative navigation systems, and the advancement of minimally invasive approaches. The review evaluates the ongoing debate between anatomical versus non-anatomical resection and examines the emerging role of robotic surgery. In liver transplantation, expanded criteria beyond the Milan criteria show promising outcomes, while the integration of novel biomarkers and imaging techniques improves patient selection. The role of preoperative and adjuvant therapies is increasingly important, with recent trials demonstrating the potential of immune checkpoint inhibitors combined with anti-VEGF agents in both settings. Despite these advances, postoperative recurrence remains a significant challenge. The review concludes that successful HCC treatment requires a personalized approach, integrating surgical expertise with emerging technologies and systemic therapies while considering individual patient factors and regional variations in practice patterns.
Exploring climate-driven phenological mismatches in pears, pests and natural enemies: a multi-model approach
Authors: Reeves Laura A. , Belien Tim , Senapathi Deepa , Garratt Michael P. D. , Fountain Michelle T. 
Published: February 2025

Abstract
Pear psyllid (Cacopsylla pyri) is the dominant pest of UK pear orchards, with an estimated cost of £5 million per annum. Insecticide withdrawal and increased pesticide resistance of C. pyri have led many growers to depend more on natural enemies for pest management, including earwigs. However, there is concern how phenological events may shift with future climate change, which may result in phenological mismatches. This study aimed to determine shifts in timing of phenological events within an agroecosystem and predict phenological mismatches or synchronies between trophic levels. We evaluated three models: the C. pyri phenology model, the earwig degree day model and the PhenoFlex model (flowering time). Phenological events predicted by models included: first, full and last flowering time for Pyrus communis; peak psyllid abundance date for first-generation (G1) C. pyri nymphs and second-generation (G2) eggs, nymphs and adults; and peak abundance date for stage 4 Forficula auricularia and adults. Findings indicated that the timing of phenological events was advancing for all trophic levels, becoming significantly earlier under the current time period. Furthermore, predictions indicated that timing events would continue to advance under the RCP8.5 scenario. However, not all phenological events advanced at the same rate; the date of peak C. pyri G1 nymph abundance advanced at a higher rate than full flowering time, which could result in a phenological mismatch by 2071. Conversely, C. pyri and F. auricularia showed phenological synchrony, with peak abundance dates advancing at a similar rate, which could be beneficial for future biological control.
Choking/Strangulation During Sex: Understanding and Negotiating “Safety” Among 18-35 Year Old Australians
Authors: Conte Isabella , Sharman Leah S. , Douglas Heather 
Published: February 2025

Abstract
Despite its potentially fatal consequences, sexual choking/strangulation is an increasingly common sexual practice. Existing research suggests that its growing prevalence is partly a consequence of its popular construction as “risky yet safe.” Few studies have directly examined how people frame and engage in choking/strangulation in terms of “safety”—what people think it means for strangulation to be (or not be) “safe” and how people think safety during strangulation can be achieved. Drawing on qualitative text responses from a survey collected in 2023, this paper examined whether and how Australian adults aged between 18–35 perceived choking/strangulation in terms of “safety.” We identified and discussed four main themes arising from the data: choking/strangulation during sex can be safe; pressure/intensity is a safety mechanism; consent is a safety mechanism; and trust and communication are necessary. In consideration of these themes, we suggest that many Australian young people are not aware of the risks of choking/strangulation during sex and frequently equate pressure/intensity and consent, within a trusting relationship, with safety. Given the significant risks and harms associated with any sexual choking/strangulation and the resultant difficulty in achieving safe use, we concluded that appropriate education and information should be provided to young people.
Solar orbiter: a short review of the mission and early science results
Authors: Harra Louise , Müller Daniel 
Published: February 2025

Abstract
On 9 February 2020 at 11:03 pm EST, an Atlas V 411 rocket launched the ESA/ NASA Solar Orbiter mission. This mission was the culmination of decades of work across many countries to achieve the goal of getting close to the Sun and measuring how the Sun creates and maintains the heliosphere. The mission’s goal is to understand how the inner heliosphere works and how solar activity impacts it. The spacecraft achieves this with a specially designed highly elliptical orbit that gets close to the Sun twice a year. It reaches as close as 0.28 au requiring a novel heat shield to protect the instruments from the intense heat (the front side of the heat shield reaches around 500 ∘C at this location). There are ten scientific instruments onboard: Six remote-sensing instruments observe solar activity across the electromagnetic spectrum on small and large scales, including imaging the source regions of the solar wind. They are accompanied by four in-situ instruments to probe the properties of the solar wind as it flows past the spacecraft. This review paper describes a selection of results from Solar Orbiter during its cruise phase and the beginning of its nominal scientific operations phase, and looks towards the next phases of the mission, when the spacecraft leaves the ecliptic plane to observe the solar poles for the first time.
Associations between lifestyle factors, physiological conditions, and epigenetic age acceleration in an Asian population
Authors: Wu Yu-Ru , Lin Wan-Yu 
Published: February 2025

Abstract
Epigenetic clocks use DNA methylation (DNAm) levels to predict an individual’s biological age. However, relationships between lifestyle/biomarkers and epigenetic age acceleration (EAA) in Asian populations remain unknown. We here explored associations between lifestyle factors, physiological conditions, and epigenetic markers, including HannumEAA, IEAA, PhenoEAA, GrimEAA, DunedinPACE, DNAm-based smoking pack-years (DNAmPACKYRS), and DNAm plasminogen activator inhibitor 1 level (DNAmPAI1). A total of 2474 Taiwan Biobank (TWB) individuals aged between 30 and 70 provided physical health examinations, lifestyle questionnaire surveys, and blood and urine samples. Partial correlation analysis (while adjusting for chronological age, smoking, and drinking status) demonstrated that 29 factors were significantly correlated with at least one epigenetic marker (Pearson’s correlation coefficient |r|> 0.15). Subsequently, by exploring the model with the smallest Akaike information criterion (AIC), we identified the best model for each epigenetic marker. As a DNAm-based marker demonstrated to predict healthspan and lifespan with greater accuracy, GrimEAA was also found to be better explained by lifestyle factors and physiological conditions. Totally 15 factors explained 44.7% variability in GrimEAA, including sex, body mass index (BMI), waist-hip ratio (WHR), smoking, hemoglobin A1c (HbA1c), high-density lipoprotein cholesterol (HDL-C), creatinine, uric acid, gamma-glutamyl transferase (GGT), hemoglobin, and five cell-type proportions. In summary, smoking, elevated HbA1c, BMI, WHR, GGT, and uric acid were associated with more than one kind of EAA. At the same time, higher HDL-C and hemoglobin were related to epigenetic age deceleration (EAD). These findings offer valuable insights into biological aging.
Risk management, digital technology literacy, and modern learning environments in enhancing learning innovation performance: A framework for higher education
Authors: Setyadi Antonius , Pawirosumarto Suharno , Damaris Alana , Dharma Robby 
Published: February 2025

Abstract
This study aims to explore the influence of risk management and digital technology literacy on learning innovation performance, with a particular focus on the moderating role of modern learning environments. The research employs a quantitative approach using data collected from 385 Indonesian university students, analyzed through Structural Equation Modeling-Partial Least Squares (SEM-PLS) to validate the proposed framework. The results demonstrate that effective risk management significantly enhances institutional adaptability and fosters success in implementing innovative learning strategies. Moreover, higher levels of digital technology literacy empower students to engage more effectively with modern learning technologies, leading to improved performance outcomes. The findings also highlight that the moderating effect of modern learning environments strengthens these relationships, underscoring the importance of robust digital infrastructure and adaptive pedagogy. This study provides theoretical contributions by integrating risk management, digital literacy, and innovation within the context of education. Practical implications include recommendations to optimize risk management frameworks, enhance digital literacy programs, and invest in modern learning ecosystems to support academic success and institutional resilience.
Discovery and Field Evaluation of Sex Pheromone Components for the Click Beetle Melanotus verberans (LeConte) (Coleoptera: Elateridae)
Authors: Williams III Livy , Halloran Sean T. , Baker Paul D. , Etzler Frank E. , Lawrence Lance L. , Millar Jocelyn G. 
Published: February 2025

Abstract
Wireworms, the larval stage of elaterid beetles, are among the most serious soil-borne insect pests in the world. Wireworms feed on a variety of key crops, including small grains, maize, vegetables, fruits, sugar cane, sugar beets, potatoes, and sweet potatoes. Management of these pests is becoming increasingly problematic, in part due to knowledge gaps in their basic biology, which hinders development of effective crop protection strategies. In particular, little is known about the semiochemicals that mediate the reproductive behavior of these pests. Research over the past two decades has begun to fill this need, with: (1) the discovery of sex attractants for several key pest species, and (2) subsequent studies toward development of semiochemically-based pest management approaches. We used chemical and behavioral studies to identify, synthesize, and field test the sex attractant pheromone of adult Melanotus verberans, the larvae of which are important crop pests. In coupled gas chromatography-mass spectrometry analyses of extracts of ovipositors of females, five possible pheromone components were identified. Subsequent coupled gas chromatography-electroantennogram detection analyses indicated that male antennae were responsive to only two of these compounds, 13-tetradecenyl acetate and 13-tetradecenyl hexanoate. In field trials, neither compound alone was attractive, but a blend of the two was strongly attractive to conspecific male beetles, and did not attract other species. A two-year field study showed that most male beetle flight activity occurred from April through May. Because the sex pheromone of M. verberans consists of two compounds that can be readily synthesized, its development for integrated pest management should be economically feasible.
Synthesis, Characterization, and Electrical Properties of CdO-Doped Polyaniline for Enhanced Hole Extraction and Performance in Inverted Perovskite Solar Cells
Authors: Abozid Ashraf , Elseman Ahmed Mourtada , Elnaggar Elsayed M. , Hassan Ali M. 
Published: February 2025

Abstract
PEDOT: PSS is recognized as one of the most conductive polymers used as an organic hole transport layer (HTL) in inverted perovskite solar cell (PSC) structures. However, its acidic nature and valence band mismatch with the adjacent perovskite layer often led to reduced efficiency and lower open-circuit voltage (VOC) in PSCs. To address these limitations, we incorporated polyaniline (PANI) doped with varying amounts of CdO (x = 0, 1, 5, and 10%), referred to as PANI-CdO (x%). The synthesized CdO samples were thoroughly characterized using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Fourier transform infrared spectroscopy (FTIR), Raman spectroscopy, scanning electron microscopy (SEM), and transmission electron microscopy (TEM). Electrical measurements demonstrated that the addition of CdO enhanced the conductivity and mobility of PANI, contributing to the improved performance of the PSCs. Specifically, the device incorporating the CdO (5%)-doped PANI exhibited superior power conversion efficiency (PCE) of 14.71%, compared to 13.38% for the pristine PEDOT: PSS device. Additionally, VOC increased from 1.02 V (pristine PEDOT: PSS) to 1.11 V (CdO 5% doped PANI), reflecting better energy band alignment and reduced recombination losses. Furthermore, the short-circuit current density (JSC) also improved from 17.01 mA/cm2 to 17.67 mA/cm2, indicating enhanced charge extraction and transport efficiency.

Graphical Abstract
Can camera traps predict habitat-species associations? A comparison with GPS-based habitat selection in red deer
Authors: Donini Valerio , Pedrotti Luca , Ferretti Francesco , Iacona Elisa , Lorenzetti Lucrezia , Nelli Luca , Cozzi Francesca , Corlatti Luca 
Published: February 2025

Abstract

Context
Camera traps are widely used in ecological studies, including analyses of habitat use. However, the relationships between animal spatial behavior and landscape features obtained with camera traps have seldom been compared to those obtained with more established methods.

Objectives
We evaluated the use of camera trap data to predict habitat use in red deer Cervus elaphus by comparing them to GPS telemetry data, used as a benchmark.

Methods
Within a 100 km2 study area in the Stelvio National Park (Italy), we collected red deer presence data from 50 camera traps from 2019 to 2023. In addition, 23 deer (15 females and 8 males) were equipped with global positioning system collars. For both types of data, we modeled presence/absence as a function of environmental variables using a generalized linear mixed modeling approach. Model estimates were compared in terms of directionality of the effects and of predicted habitat suitability.

Results
We found a higher concordance of effect directionality and predicted suitability for females than for males, possibly due to limited sample size in the latter. Discrepancies were found in specific habitat relationships and may be due to inherent differences between telemetry-based and camera trap-based data.

Conclusions
Our results suggest that camera trap data can capture coarse-scale patterns of habitat use, whereas telemetry data are more suitable for finer-scale analyses. The choice of which method to use depends on the research objectives.
The haloing effect of fast-rotating space tethers
Authors: Lara Martin 
Published: February 2025

Abstract
The dynamics of classical mass-point orbits is changed when using cable-connected satellites. If long enough, tethers in fast rotation have stabilizing characteristics that make them appealing for satellite missions involving unstable dynamics. Using Hamiltonian formulation and with the help of perturbation methods, we reduce the dynamics about the collinear points of the Hill problem approximation to the restricted three-body problem to just one degree of freedom. The integrable dynamics maps orbits of the tether’s center of mass onto points on the sphere, and demonstrates the haloing effect stemming from the orbit-attitude coupling of the fast-rotating configuration. Indeed, it is shown that halo orbits are generated in regions in which the natural dynamics would prevent them to exist, by modifying the tether’s length.
Interpolation Properties for the Bimodal Provability Logic $$\textbf{GR}$$
Authors: Kogure Haruka , Kurahashi Taishi 
Published: February 2025

Abstract
We study interpolation properties for Shavrukov’s bimodal logic

$$\textbf{GR}$$

GR

of usual and Rosser provability predicates. For this purpose, we introduce a new sublogic

$$\textbf{GR}^\circ $$

GR
∘

of

$$\textbf{GR}$$

GR

and its relational semantics. Based on our new semantics, we prove that

$$\textbf{GR}^\circ $$

GR
∘

and

$$\textbf{GR}$$

GR

enjoy Lyndon interpolation property and uniform interpolation property. As a consequence of our proofs, we obtain the completeness and the finite frame property of

$$\textbf{GR}^\circ $$

GR
∘

and

$$\textbf{GR}$$

GR

with respect to our new semantics.