bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of socioeconomic status on enrollment in clinical trials for cancer: A systematic review
Authors: Donzo Maja Wichhart , Nguyen Grace , Nemeth John K. , Owoc Maryanna S. , Mady Leila J. , Chen Amy Y. , Schmitt Nicole C. 
Published: January 2024

AbstractBackgroundTo achieve equitable access to cancer clinical trials (CCTs), patients must overcome structural, clinical, and attitudinal barriers to trial enrollment. The goal of this systematic review was to study the relationship between socioeconomic status (SES), assessed either by direct or proxy measures, and CCT enrollment.MethodsThe review team and medical librarian developed search strategies for each database to identify studies for this systematic review, which was conducted according to PRISMA guidelines. Inclusion criteria were as follows: studies published in relevant scientific journals between January 2000 and July 2022, primary sources, English literature, and studies conducted in the US. Sixteen studies fulfilled the inclusion criteria and were reviewed. The risk of bias assessment was conducted independently by two reviewers using the Newcastle Ottawa scale.ResultsThe initial search yielded 4070 citations, and 16 studies were included in our review. Four of the studies included used patient reported annual income as a measure of SES, while the remaining 12 studies used patient zip code as a proxy measurement of SES. Consistent with our hypothesis, 13 studies showed a positive association between high SES (patient‐reported or proxy measurement) and CCT enrollment. Two studies showed a negative association, and one study showed no relationship.ConclusionsThe existing literature suggests that low SES is associated with lower participation in CCT. The small number of studies identified on this topic highlights the need for additional research on SES and other barriers to CCT participation.
Practitioner psychologists' perspectives on working with clients with psychosis in a South‐East Asian city‐state: A qualitative investigation
Authors: Wen Siying , Mankiewicz Pawel D. 
Published: January 2024

AbstractObjectivePrevious qualitative studies have investigated the experiences of undergoing an evidence‐based psychotherapy for psychosis among individuals affected by such condition. However, the literature investigating the perspectives, experiences and needs of psychological practitioners providing the treatment remains considerably underrepresented. In the context of Asian cultures, where pervasive stigma towards psychosis and mental health services exists and interferes with proactive help‐seeking, such research appears even more pertinent. To address the gap in the existing literature, this study utilised qualitative methodology to investigate the experiences of practitioner psychologists working with clients with psychosis in a South‐East Asian city‐state.MethodSix fully qualified participants were recruited from the local mental health services via convenience sampling. Semi‐structured qualitative interviews were conducted. Transcribed verbatim data were then subjected to inductive thematic analysis.ResultsFour superordinate themes emerged, as follows: therapeutic alliance, cognitive behavioural therapy for psychosis (CBTp) as primary approach, cultural influences and needs of practitioners.ConclusionsResults indicated that both practitioner psychologists and their clients contributed collaboratively to the establishment of therapeutic alliance. Although CBTp was utilised as a principal psychotherapeutic approach, acceptance and commitment therapy (ACT) was also valued. Necessary adaptations in the treatment were reflected on to address the specificity of local cultures, including the use of language and addressing pervasive public stigma. The necessity of multidisciplinary collaboration, localised training and supervision was also expressed.
Site‐Specific Anchoring a Luminescent Tag in a Protein with Non‐Emissive Iridium(III) Complex
Authors: Guo Shu‐Li , Xiao Yu‐Hao , Pan Bin‐Bin , Su Xun‐Cheng 
Published: January 2024

AbstractSite‐specific modification of proteins with synthetic fluorescent tag effectively improves the resolution of imaging, and such a labeling method with negligible three‐dimensional structural perturbations and minimal impact on the biological functions of proteins is of high interest to dissect the high‐resolution activities of biomolecules in complex systems. To this end, several non‐emissive iridium(III) complexes [Ir(C−N)2(H2O)2]+OTF− (C−N denotes various cyclometalated ligands) were designed and synthesized. These complexes were tested for attaching a protein by coordinating to H/X (HisMet, HisHis, and HisCys) that are separated by i and i+4 in α‐helix. Replacement of the two labile water ligands in the iridium(III) complex by a protein HisHis pair increases the luminescent intensity up to over 100 folds. This labeling approach has been demonstrated in a highly specific and efficient manner in a number of proteins, and it is also feasible for labeling target proteins in cell lysates.
Left atrial appendage occlusion in patients suffering from advanced chronic kidney disease (stage 4 and 5). Long‐term follow‐up
Authors: López‐Tejero Sergio , Antúnez‐Muiños Pablo , Fraile‐Gómez Pilar , Sousa Gilles Barreira‐de , Rodríguez‐Collado Javier , Herrero‐Garibi Jesús , Blanco‐Fernández Fabián , Diego‐Nieto Alejandro , Delgado‐Lapeira Gonzalo C. , del Villar‐Moro M. Candelas Pérez , Martín‐Moreiras Javier , Sánchez‐Fernández Pedro L. , Cruz‐González Ignacio 
Published: January 2024

AbstractIntroduction and ObjectivesAdvanced chronic kidney disease (A‐CKD) combined with atrial fibrillation increases the risk of both thrombogenic and bleeding events. Left atrial appendage occlusion (LAAO) may be an alternative to oral anticoagulation to prevent thromboembolic events. We aimed to evaluate the outcomes of LAAO in patients with A‐CKD.MethodsComparison at long‐term follow‐up of patients diagnosed with and without A‐CKD (eGFR<30 mL/min/1.73 m2) who underwent LAAO between 2009 and May 2022.ResultsFive hundred seventy‐three patients were included. Eighty‐one (14%) were diagnosed with A‐CKD. There were no differences in sex, age, and cardiovascular risk factors, except for diabetes which was more frequent in patients with A‐CKD. The control group had higher rates of stroke, both ischemic and hemorrhagic. There were no differences in the CHA2DS2‐VASc score, although A‐CKD patients had a higher bleeding risk according to the HASBLED scale. Global procedural success was 99.1%. At follow‐up, there were no differences in stroke rate: at 1‐year (HR: 1.22, IC‐95%: 0.14–10.42, p = 0.861); at 5‐years (HR: 0.60, IC‐95%: 0.08–4.58, p = 0.594). Although bleeding events were higher in the A‐CKD group, no differences were found in major bleeding (defined BARC ≥ 3) at 1‐year (HR: 1.34, IC‐95%: 0.63–2.88, p = 0.464) or at 5‐years follow‐up (HR: 1.30, IC‐95%: 0.69–2.48, p = 0.434). Mortality rate at 5 years was higher in the A‐CKD patients (HR: 1.84, IC‐95%: 1.18–2.87, p = 0.012).ConclusionsLAAO is an effective and safe treatment in A‐CKD patients to prevent ischemic events and bleeding. This strategy could be an alternative to oral anticoagulation in this high‐risk group of patients.
Serratus anterior plane block and postoperative pain control in obese patients undergoing S‐ICD implantation: A case series and literature analysis
Authors: Coletta Francesco , Schettino Francesca , Tomasello Antonio , Sala Crescenzo , Pisanti Massimo , Villani Romolo 
Published: January 2024

Key Clinical MessageWe report five case series of obese patients with severe left ventricular ejection fraction impairment undergoing Serratus Anterior Plane Block during S‐ICD Implantation. This anesthesia approach has a reduced impact on the patient's hemodynamics and adequately manages postprocedural pain.AbstractSubcutaneous implantable cardioverter‐defibrillator (S‐ICD) procedures are frequently performed under analgosedation or general anesthesia, leading to prolonged postoperative hospital stays and increased costs. This anesthetic technique may also have a greater hemodynamic impact, particularly in obese and cardiac patients. However, an alternative anesthetic technique can be employed: ultrasound‐guided serratus anterior plane block (US‐SAPB). We analyzed the anesthetic clinical course in 5 patients, 3 males and 2 females, who were obese (BMI ≥ 30) and underwent S‐ICD implantation for primary prevention using a two‐incision intermuscular technique and ultrasound‐guided serratus anterior plane block. All patients had a left ventricular ejection fraction less than or equal to 35%. It significantly facilitated pain control during the procedure and, especially, in the postoperative phase. However, the data available in the literature are mostly derived from case reports and small comparative studies. Therefore, further studies with a larger sample size and direct comparison with general anesthesia or deep sedation are needed.
Manufacturing AAl2O4 (A=Cu, Co, Ni, Zn) Spinel Catalysts for Toluene Combustion: Elucidating the A‐site Replacement Effect on the Reactivity
Authors: Lv Yu , Yan Haiming , Liu Teng , Xu Junwei , Xu Xianglan , Fang Xiuzhong , Wang Xiang 
Published: January 2024

AbstractTo decode the A‐site substitution effect on the reactivity of Al‐based spinel complex oxides, a series of AAl2O4 (A=Cu, Co, Ni, Zn) compounds were manufactured and tested by toluene combustion. It was confirmed that a pure spinel crystalline phase has been successfully synthesized for all the catalysts. The toluene and CO oxidation activity are sequenced as CuAl2O4>CoAl2O4>NiAl2O4>ZnAl2O4. As discovered, both active surface O2− and acid sites are the two critical factors to determine the reactivity, which can adsorb and activate the reactants effectively to form active intermediates, possibly following a Mars‐van‐Krevelen pathway. The activity improves positively with the amount increasing of these two kinds of active sites, thus showing an evident A‐site replacement effect. CuAl2O4 owns the biggest numbers of these two kinds of active sites, thereby exhibiting the optimal catalytic activity. Moreover, it also shows good stability in a dry feed, and considerable ability to resist water vapor and sulfur poisoning. In‐situ DRIFTS results have indicated that benzyl, benzoate, benzaldehyde and benzoquinone might be the major reaction intermediates.
Research Progress and Outlook on Photocatalytic Conversion of Methane to Methanol
Authors: Jia Taikang , Wang Wenzhong 
Published: January 2024

AbstractMethane, a main component of natural gas, shale gas, and combustible ice, is widely distributed in nature. The direct conversion and efficient utilization of methane have become crucial topics within the scientific community. However, two main challenges persist in this field: methane activation and overoxidation inhibition. Recently, research on this subject has reached its pinnacle stage. Herein, we present some works addressing these concerns, particularly employing photocatalytic approaches, and with a specific focus on strategies aimed at enhancing the selectivity towards methanol as the desired product. Finally, we discuss the existing challenges and propose potential solutions for advancing direct methane‐to‐methanol conversion technology.
Effect of Gas Environment on Metal‐Support Interactions of Supported Metal Catalysts
Authors: Jin Shiqing , Wang Zhen , Li Didi , Wang Yiming , Zhu Minghui 
Published: January 2024

AbstractSupported‐metal catalysts, pivotal for industrial applications, have their catalytic properties affected by metal‐support interactions (MSIs), which notably influence both their electronic and geometric characteristics. Therefore, understanding internal and external factors that influence MSIs is crucial for the rational design of catalysts. Our minireview focuses on the effects of the gas environment on the MSIs, particularly the morphological changes in metal nanoparticles, the migrating behavior of reducible supports (strong metal‐support interaction), and the compositional rearrangement of the catalysts (reactive metal‐support interaction). Future directions are suggested to elucidate the fundamental aspects of gas environment induced structural reconstruction of catalysts, including the quantitative analysis of dynamic behavior of both the surface and interface, atomic‐level insights into the structures of the metal, support, and interface under pertinent conditions through advanced in situ/operando characterization, and the in situ manipulation of structural reconstruction.
Temperature‐Dependent Electrochemical Performance of Ta‐Substituted SrCoO3 Perovskite for Supercapacitors
Authors: Liu Guanfu , Liu Liyuan , Li Gang , Wu Shibo , He Jiahao , Zhou Yang , Demir Muslum , Ma Pianpian 
Published: January 2024

AbstractDeveloping new electrode materials with good temperature‐dependent electrochemical performance has become a great issue for the deployment of hybrid supercapacitors with wide temperature tolerance. In this work, a series of Ta‐substituted SrCo1‐xTaxO3‐δ (x=0.05, 0.10, 0.15, 0.20) perovskites have been studied as positive electrodes for hybrid supercapacitors in terms of their structures, elemental valence states and electrochemical performances. Incorporating Ta into SrCoO3‐δ perovskite not only stabilizes the crystallite structure but also notably improves electrochemical activities. The SrCo0.95Ta0.05O3‐δ@CC delivers the highest specific capacity (Qsp) of 227.91 C g−1 at 1 A g−1, which is attributed to the highest oxygen vacancy content and the fastest oxygen diffusion kinetics. The hybrid supercapacitor SrCo0.95Ta0.05O3‐δ@CC//AC@CC exhibits a high energy density of 22.82 Wh kg−1@775.09 W kg−1 and a stable long‐term cycle life (5000 cycles) with 90.7 % capacity retention. As temperature increases from 25 to 85 °C, the capacitance properties are improved at elevated temperatures for both electrode and device due to the increased electrolyte conductivity. The outstanding electrochemical results present that SrCo1‐xTaxO3‐δ perovskite holds good prospects for hybrid supercapacitors with wide temperature tolerance.
Cu‐Catalyzed Coupling of Aliphatic Amines with Alkylboronic Esters
Authors: Dennis Francesca M. , Romero Arenas Antonio , Rodgers George , Shanmugam Muralidharan , Andrews Jonathan A. , Peralta‐Arriaga Samantha L. , Partridge Benjamin M. 
Published: January 2024

AbstractWe report a Cu‐catalyzed oxidative coupling of aliphatic amines with benzylic and aliphatic boronic esters to give high value alkyl amines, products found widely in applications from medicinal chemistry to materials science. This operationally simple reaction, which can be performed on gram scale, runs under mild conditions and exhibits broad functional group tolerance. The terminal oxidant of the reaction is O2 from the air, avoiding the need for additional chemical oxidants. Investigation into the reaction mechanism suggests that the boronic ester is activated by an aminyl radical, formed through oxidation of the amine by the Cu catalyst, to give a key alkyl radical intermediate. To demonstrate its utility and potential for late‐stage functionalization, we showcase the method as the final step in the total synthesis of a TRPV1 antagonist.
Insights into the hydrodynamics in the annular pipe of industrial‐scale top‐blown smelting furnace
Authors: Wan Zhanghao , Yang Shiliang , Tang Duzuo , Yuan Haibin , Hu Jianhang , Wang Hua 
Published: January 2024

AbstractThe coaxial jet consisting of swirl jet and axial jet plays a critical role in the industrial processes but is rarely investigated; therefore, it is numerically explored by means of the computational fluid dynamics (CFD) approach in the present work. The force on the swirler, axial and tangential velocity at the annular pipe outlet, and the spatial distribution of swirl number (SN) are selected to evaluate the effect of geometrical parameters on the swirling performance. The results clarify that the velocity and their azimuthal components in the transverse cross‐section can be categorized into six segments based on high/low velocity values. The coaxial jets form a weak swirl with high axial, certain tangential, and low radial velocities. x‐ and y‐vorticity vary within −200 to 200 s−1. Coaxial jet mixing decays the SN. Based on the multi‐objective matrix analysis, swirler height has the largest effect on swirl performance followed by diameter, angle, and number based on analysis. Optimal parameters are 130° vane angle, 240 mm diameter, 10 vanes, and 250 mm height of the swirler.
HeteroPP: A directive‐based heterogeneous cooperative parallel programming framework
Authors: Wan Lanjun , Cui Xueyan , Li Yuanyuan , Zheng Weihua , Yuan Xinpan 
Published: January 2024

AbstractHeterogeneous platforms composed of multiple different types of computing devices (such as CPUs, GPUs, and Intel MICs) have been widely used recently. However, most of parallel applications developed in such a heterogeneous platform usually only utilize a certain kind of computing device due to the lack of easy‐to‐use heterogeneous cooperative parallel programming models. To reduce the difficulty of heterogeneous cooperative parallel programming, a directive‐based heterogeneous cooperative parallel programming framework called HeteroPP is proposed. HeteroPP provides an easier way for programmers to fully exploit multiple different types of computing devices to concurrently and cooperatively perform data‐parallel applications on heterogeneous platforms. An extension to OpenMP directives and clauses is proposed to make it possible for programmers to easily offload a data‐parallel compute kernel to multiple different types of computing devices. A source‐to‐source compiler is designed to help programmers to automatically generate multiple device‐specific compute kernels that can be concurrently and cooperatively performed on heterogeneous platforms. Many experiments are conducted with 12 typical data‐parallel applications implemented with HeteroPP on a heterogeneous CPU‐GPU‐MIC platform. The results show that HeteroPP not only greatly simplifies the heterogeneous cooperative parallel programming, but also can fully utilize the CPUs, GPU, and MIC to efficiently perform these applications.
An examination of adults with atypical anorexia nervosa at admission to treatment at higher levels of care: An attempt to increase diagnostic clarity
Authors: Manwaring Jamie L. , Blalock Dan V. , Duffy Alan , Le Grange Daniel , Mehler Philip S. , Riddle Megan , Rienecke Renee D. 
Published: January 2024

AbstractObjectiveAnorexia nervosa (AN) is a serious illness with a high mortality rate and multiple physiological complications. The vague definition of atypical AN allows for subjective interpretation. This retrospective study aimed to focus future research on the operational definition of atypical AN by examining four factors associated with atypical AN at admission to higher level of care treatment.MethodsAdults with atypical AN (n = 69) were examined within sample analyses among four groups: (1) >10% versus ≤10% weight loss; (2) weight loss within the previous 3 months versus >3 months; (3) engaging in purging behaviors versus absence of purging behaviors; and (4) endorsing versus not endorsing significant cognitive aspects of AN.ResultsPatients with atypical AN endorsed elevated ED cognitions on the Eating Disorder Examination‐Questionnaire and depressive symptoms; a lack of association was found between weight loss severity and weight loss time frame with depressive symptoms, eating concern, and restraint. Purging behavior was associated with a higher expected body weight percentage (%EBW) and dietary restraint, while greater AN cognitions were associated with a higher EBW and weight loss percentage. Few patients demonstrated bradycardia, hypophosphatemia, or amenorrhea.DiscussionThis study demonstrated the severity of ED cognitions and depressive symptoms in this atypical AN sample and provided directions for future studies in the nosology of atypical AN. It may be important to distinguish between individuals with atypical AN who are purging and those who are not. Atypical AN was associated with a low frequency of physiological disturbances.Public SignificanceThis study provides further clarification regarding the operational definition of atypical AN; currently, a constellation of symptoms under Other Specified Feeding or Eating Disorders. This study was consistent with previous research in reporting severe eating disorder cognitions in adults with atypical AN, and noted the potential importance of distinguishing a purging distinction. A minority of patients in this study had physiological impairments.
A policy portfolio approach to plastics throughout their life cycle: Supranational and national regulation in the European Union
Authors: Eckert Sandra , Karassin Orr , Steinebach Yves 
Published: January 2024

AbstractThe environmental and health problems caused by plastics throughout their life cycle have attracted considerable public attention over the past decade, triggering policy responses in many constituencies. Similarly, interdisciplinary research on plastics has been burgeoning in the past few years, and political science contributions have covered the manifold root causes and consequences of this shift in public policy including media coverage, evolving discourses and policy agendas. In view of this policy relevance that drives scholarly inquiry, it is surprising that we lack a systematic assessment of the actual policy outputs. This article fills this lacuna by developing a policy portfolio approach to plastic regulation. To illustrate and substantiate our approach, we provide an exploratory analysis of EU plastics regulation over the last twenty years, complementing this with Denmark, Germany, and Poland as diverse cases of member state regulation. Overall, our research shows that the number of policy measures targeting plastics has massively increased both at the supranational and national level. This policy growth, however, varies across policy targets and instruments. Our findings highlight first, that the policy targets addressed are mainly located at the end of the plastics life cycle; and second, that the instrument choice is privileging the use of hierarchical forms of intervention over the use of market‐ or information‐based instruments. We discuss these features of the policy portfolio approach in light of existing research on plastics and life‐cycle‐oriented policy approaches such as the Circular Economy.
Multi‐Color Magnetic Circularly Polarized Luminescence from Achiral Perovskite (Cs+Pb2+X3) Quantum Dots
Authors: Amasaki Ryo , Kitahara Maho , Tanaka Senku , Imai Yoshitane 
Published: January 2024

AbstractHigh‐performance optoelectronic materials require luminescent materials capable of intense photoluminescence (PL). However, controlling the optical properties of luminescent materials requires complex synthesis and purification procedures. Herein, we propose a simple method for obtaining circularly polarized luminescence from achiral inorganic quantum dots. This method involves applying north‐up and south‐up 1.7 T magnetic fields at 25 °C to five types of achiral antimagnetic perovskite‐Pb‐quantum dots in a solution state. The wavelengths of magnetic circularly polarized luminescence (MCPL) and PL of achiral perovskite‐Pb quantum dots were successfully controlled according to the type and composition ratio of halogen ions. The magnitude of MCPL, gMCPL, was on the order of |gMCPL|=10−3 in a wavelength range of 406–697 nm. Although the perovskite‐Pb‐quantum dots were achiral, the rotation direction of the MCPL could be controlled by varying the direction of the applied magnetic field.