bluuebunny/crossref_metadata_2025_split huggingface dataset:
A high urinary urobilinogen/serum total bilirubin ratio indicates acute hepatic porphyria in patients with abdominal pain
Authors: Song Chengyuan , Liu Yuan 
Published: December 2023

AbstractAcute hepatic porphyria (AHP) has always been a diagnostic dilemma for physicians due to its variable symptoms. Correct diagnosis mainly depends on the detection of an elevated urinary porphobilinogen (PBG), which is not a routine test and highly relies on the physician’s awareness of AHP. In the present study, we identified a more convenient indicator during routine examinations to improve the diagnosis of AHP. We found that AHP patients showed a significant higher “FALSE” urinary urobilinogen level caused by urinary PBG during the urinalysis when detected by strips impregnated with Ehrlich reagent (P < 0.05). And a remarkable increase in the urinary urobilinogen/serum total bilirubin ratio was observed in AHP patients. The area under the ROC curve of this ratio for AHP was 1.000 (95% confidence interval 1.000–1.000, P < 0.01). A cutoff value of 3.22 for this ratio yielded a sensitivity of 100% and a specificity of 100% to distinguish AHP patients from the controls. Thus, we proved that a “falsely” high urinary urobilinogen level that was adjusted by the serum total bilirubin level (urinary urobilinogen/serum total bilirubin ratio) could be used as a sensitive and specific screening marker for AHP in patients with abdominal pain.
A novel surgical strategy of three column osteotomy at non-lesioned area for correcting severe angular kyphosis due to Pott’s disease: a retrospectively study
Authors: Zhao Deng , Wang Fei , Hu Zhengjun , Zhong Rui , Huang Huaqiang , Zhang Zhong , Jiang Dengxu , Liang Yan , Liang Yijian 
Published: December 2023

AbstractSevere sharp angular kyphosis resulting from Pott’s disease typically necessitates surgical intervention. The deployment of three-column osteotomy within the lesion and apical regions has been validated as an effective modality for the amelioration of angular kyphosis. Nonetheless, a propensity for residual kyphosis persists, accompanied by a significant perioperative risk profile. In pursuit of optimizing correctional outcomes and diminishing complication rates, we proposed an innovative surgical approach, utilizing osteotomy in the non-lesioned zones for the rectification of severe angular kyphosis associated with Pott’s disease. This retrospective investigation encompasses 16 subjects who underwent this novel surgical tactic, involving osteotomies in non-lesioned vertebral segments, at our institution from 2016 to 2018. Radiographic measures, encompassing kyphotic angle and sagittal vertical axis (SVA), were documented at baseline and during terminal follow-up. Neurological status was evaluated via the American Spinal Injury Association (ASIA) grading system. Operative duration, volume of hemorrhage, and perioperative complications were systematically recorded. The cohort included 6 males and 10 females with an average age of 30.7 ± 11.41 years. Follow-up intervals spanned 24 to 42 months. Mean operative time and blood loss were 492 ± 127.3 min and 1791 ± 788.8 ml, respectively. The kyphotic angle improved from 97.6 ± 14.6° to 28.8 ± 18.70°. In cases with lumbar afflictions, vertebral restoration was achieved (L1–L5 and L2–S1). Initial mean SVA of 6.7 ± 3.58 cm was reduced to 3.3 ± 1.57 cm at follow-up. Neurological function enhancement was observed in six patients, while ten maintained baseline status. Complication rates, including wound infection and rod fracture at 12 months, were observed in approximately 11.8% of cases. Our findings suggest that the surgical strategy is both effective and safe for addressing severe angular kyphosis due to Pott’s disease, contingent upon the expertise of the surgical unit.
Dual‐polarised end‐fire antenna based on the high‐order mode of spoof surface plasmon polaritons
Authors: Liang Zheng , Qi Shi‐Shan , Wu Wen 
Published: December 2023

AbstractA planar antenna with dual‐linearly polarised end‐fire radiation is proposed. A tapered double‐sided symmetrical spoof surface plasmon polariton (SSPP) transmission line (TL) with tilted unit cells is proposed. The SSPP TL can operate in two types of first high‐order modes: the first high‐order even mode and the first high‐order odd mode. A two‐port feeding structure is designed to feed the SSPP TL. When the signal is fed from port 1, the energy travels through the substrate integrated waveguide and eventually excites the even mode on the SSPP TL, leading to vertically polarised radiation. Conversely, when the signal is input from port 2, the energy travels through the stripline‐to‐slotline transition and eventually excites the odd mode on the SSPP TL, generating horizontally polarised radiation. According to the measured results, a 54.6% overlapping bandwidth is obtained. The horizontal and the vertical polarisations achieve a maximum gain of 14.7 and 12.2 dBi, respectively.
Relevanz der Vitamin D-Messung in der
Patientenbetreuung
Authors: Scharla Stephan 
Published: December 2023

ZusammenfassungVitamin D und seine Metaboliten sind für den Knochen- und
Mineralstoffwechsel, aber auch für andere Organsysteme, von
großer Bedeutung. Zur Diagnostik eines Vitamin D Mangels wird die
Bestimmung des 25-hydroxyvitamin D im Serum oder Plasma verwendet. Allerdings
sind die Messmethoden (Assays) nicht sehr gut standardisiert und
anfällig für Störfaktoren. Überdies wird von
vielen Methoden nicht nur das 25-hydroxyvitamin D erfasst, sondern auch andere
Vitamin D-Metaboliten. Ein generelles Screening auf Vitamin D-Mangel wird
für die allgemeine Bevölkerung nicht empfohlen, sondern nur
für Risikogruppen und für ältere Menschen. Auch
für Patienten mit Osteoporose wird die Messung von 25-hydroxyvitamin D
nur bei V.a. Vitamin-D-Mangel und Osteomalazie empfohlen. Im Verlauf einer
medikamentösen Behandlung mit Vitamin D kann bei V.a. Malabsorption oder
anderen Problemen ein Monitoring von 25-hydroxyvitamin D im Therapieverlauf
sinnvoll sein. Bei speziellen Fragestellung (z. B.
Hypercalciämie) kann auch die Bestimmung von 1,25-dihydroxyvitamin D und
24,25-dihydroxyvitamin D notwendig sein.
MnFe2O4/polyaniline/diatomite composite with multiple loss mechanisms towards broadband absorption
Authors: Ge Yao , Guo Wanmi , Huang Qinglin , Tao Shanjun , Ji Haixia , Ren Qifang , Chen Yue’e , Chen Jing , Jia Xinyu , Ding Yi 
Published: December 2023

The research and development of absorbing materials with high absorbing capacity, wide effective absorption bandwidth, and lightweight has always been interesting. In this research, a facile hydrothermal method was used to prepare MnFe2O4, and the grain size of MnFe2O4 decreased with increasing hydrothermal temperature. When the size of MnFe2O4 nanoparticles is less than 10 nm, its quantum size effect and surface effect make its electromagnetic microwave absorption performance greatly optimized. When the thickness of MnFe2O4-110 °C is 2.57 mm, the minimum reflection loss (RLmin) is −35.28 dB. Based on this, light porous diatomite and a three-dimensional polyaniline network are introduced. Diatomite is used as the base material to effectively reduce the agglomeration of MnFe2O4 quantum dots. The relatively high surface area introduced by a three-dimensional network of polyaniline promotes the orientation, interfacial polarization, multiple relaxation, and impedance matching, thereby generating further dielectric loss. Additionally, the magnetic properties of manganese ferrite and the strong electrical conductivity of polyaniline play an appropriate complementary role in electromagnetic wave absorption. The RLmin of MnFe2O4/PANI/diatomite is −56.70 dB at 11.12 GHz with an absorber layer thickness of 2.57 mm. The effective frequency bandwidth (RL &lt; −10 dB) ranges from 9.21 to 18.00 GHz. The absorption mechanism indicates that the high absorption intensity is the result of the synergistic effect of impedance matching, conduction losses, polarization losses, and magnetic losses.
Greening vegetation cools mean and extreme near-surface air temperature in China
Authors: Cao Yipeng , Guo Weidong , Ge Jun , Liu Yu , Chen Chaorong , Luo Xing , Yang Limei 
Published: December 2023

Abstract
Satellite observations have shown evident vegetation greening in China during the last two decades. The biophysical effects of vegetation changes on near-surface air temperature (SAT) remain elusive because prior studies focused on the effects on land surface temperature (LST). SAT is more relevant to climate mitigation and adaptation, as this temperature is experienced by humans. Here, we provide the first observational evidence of the greening effects on SAT and SAT extremes in China during 2001–2018 using the ‘space-for-time’ method. The results show a negative SAT sensitivity to greening (–0.35 °C m2 m–2) over China and a cooling effect of −0.08 °C on SAT driven by vegetation greening during the study period. Such a cooling effect is stronger on high SAT extremes, particularly over arid/semiarid areas, where greening could bring an additional cooling of −0.04 °C on the hottest days. An attribution analysis suggests that the main driving factor for the cooling effect of greening is the evapotranspiration change for arid/semiarid regions and the aerodynamic resistance change for humid regions. This study reveals a considerable climate benefit of greening on SAT, which is more concerned with natural and human system health than the greening effects on LST.
VIGA: a one-stop tool for eukaryotic virus identification and genome assembly from next-generation-sequencing data
Authors: Fu Ping , Wu Yifan , Zhang Zhiyuan , Qiu Ye , Wang Yirong , Peng Yousong 
Published: December 2023

Abstract
Identification of viruses and further assembly of viral genomes from the next-generation-sequencing data are essential steps in virome studies. This study presented a one-stop tool named VIGA (available at https://github.com/viralInformatics/VIGA) for eukaryotic virus identification and genome assembly from NGS data. It was composed of four modules, namely, identification, taxonomic annotation, assembly and novel virus discovery, which integrated several third-party tools such as BLAST, Trinity, MetaCompass and RagTag. Evaluation on multiple simulated and real virome datasets showed that VIGA assembled more complete virus genomes than its competitors on both the metatranscriptomic and metagenomic data and performed well in assembling virus genomes at the strain level. Finally, VIGA was used to investigate the virome in metatranscriptomic data from the Human Microbiome Project and revealed different composition and positive rate of viromes in diseases of prediabetes, Crohn’s disease and ulcerative colitis. Overall, VIGA would help much in identification and characterization of viromes, especially the known viruses, in future studies.
Burden of atopic dermatitis in paediatric patients: an international cross-sectional study
Authors: Weidinger Stephan , Simpson Eric L , Silverberg Jonathan I , Barbarot Sebastien , Eckert Laurent , Mina-Osorio Paola , Rossi Ana B , Brignoli Lysel , Mnif Tarek , Guillemin Isabelle , Fenton Miriam C , Delevry Dimittri , Chuang Chien-chia , Pellan Marine , Gadkari Abhijit 
Published: December 2023

Abstract

Background
Few large-scale international studies have broadly characterized the burden of atopic dermatitis (AD) across age groups among children and adolescents.

Objectives
To better characterize the AD burden in paediatric patients by disease severity.

Methods
This cross-sectional, web-based survey of paediatric patients (6 months to &lt; 18 years old) was conducted in 18 countries representing North America, Latin America, Europe, Middle East/Eurasia and East Asia. Patients with diagnosed AD were identified based on the International Study of Asthma and Allergies in Childhood criteria and self-/parent-report of ever being told by a physician that they or their child had eczema. AD severity was assessed using the Patient-Oriented Eczema Measure and Patient Global Assessment. Outcomes included measures of itch, skin pain, sleep, health-related quality of life (HRQoL), missed school days and atopic comorbidities.

Results
The survey included 1489 children aged 6 months to &lt; 6 years; 2898 children aged 6 to &lt; 12 years; and 3078 adolescents aged 12 to &lt; 18 years diagnosed with AD. Although the burden of mild AD was substantial, paediatric patients with moderate or severe AD had more itch, skin pain, sleep problems and impaired HRQoL, and missed more school days relative to those with mild AD; greater burden was observed among those with severe relative to moderate AD. At least one atopic comorbidity was present in 92.5% of all respondents.

Conclusions
These results highlight the burden of AD in paediatric patients, especially those with moderate-to-severe disease, and suggest the need for assessments that include the impact of AD on function and daily life.
Brain connectivity and academic skills in English learners
Authors: Nugiel Tehila , Demeter Damion V , Mitchell Mackenzie E , Garza AnnaCarolina , Hernandez Arturo E , Juranek Jenifer , Church Jessica A 
Published: December 2023

AbstractEnglish learners (ELs) are a rapidly growing population in schools in the United States with limited experience and proficiency in English. To better understand the path for EL’s academic success in school, it is important to understand how EL’s brain systems are used for academic learning in English. We studied, in a cohort of Hispanic middle-schoolers (n = 45, 22F) with limited English proficiency and a wide range of reading and math abilities, brain network properties related to academic abilities. We applied a method for localizing brain regions of interest (ROIs) that are group-constrained, yet individually specific, to test how resting state functional connectivity between regions that are important for academic learning (reading, math, and cognitive control regions) are related to academic abilities. ROIs were selected from task localizers probing reading and math skills in the same participants. We found that connectivity across all ROIs, as well as connectivity of just the cognitive control ROIs, were positively related to measures of reading skills but not math skills. This work suggests that cognitive control brain systems have a central role for reading in ELs. Our results also indicate that an individualized approach for localizing brain function may clarify brain-behavior relationships.
Transcranial ultrasound stimulation selectively affects cortical neurovascular coupling across neuronal types and LFP frequency bands
Authors: Su Zhaocheng , Liu Mengyang , Yuan Yi , Jiao Honglei 
Published: December 2023

Abstract
Previous studies have affirmed that transcranial ultrasound stimulation (TUS) can influence cortical neurovascular coupling across low-frequency (0–2 Hz)/high-frequency (160–200 Hz) neural oscillations and hemodynamics. Nevertheless, the selectivity of this coupling triggered by transcranial ultrasound stimulation for spike activity (&gt; 300 Hz) and additional frequency bands (4–150 Hz) remains elusive. We applied transcranial ultrasound stimulation to mice visual cortex while simultaneously recording total hemoglobin concentration, spike activity, and local field potentials. Our findings include (1) a significant increase in coupling strength between spike firing rates of putative inhibitory neurons/putative excitatory neurons and total hemoglobin concentration post-transcranial ultrasound stimulation; (2) an ~ 2.1-fold higher Pearson correlation coefficient between putative inhibitory neurons and total hemoglobin concentration compared with putative excitatory neurons and total hemoglobin concentration (*P &lt; 0.05); (3) a notably greater cross-correlation between putative inhibitory neurons and total hemoglobin concentration than that between putative excitatory neurons and total hemoglobin concentration (*P &lt; 0.05); (4) an enhancement of Pearson correlation coefficient between the relative power of γ frequency band (30–80 Hz), hγ frequency band (80–150 Hz) and total hemoglobin concentration following transcranial ultrasound stimulation (*P &lt; 0.05); and (5) strongest cross-correlation observed at negative delay for θ frequency band, and positive delay for α, β, γ, hγ frequency bands. Collectively, these results demonstrate that cortical neurovascular coupling evoked by transcranial ultrasound stimulation exhibits selectivity concerning neuronal types and local field potential frequency bands.
Reducing working hours: shorter days or fewer days per week? Insights from a 30-hour workweek experiment
Authors: Mullens Francisca , Glorieux Ignace 
Published: December 2023

Abstract
Recently, more and more experiments with a reduction in working time are taking place. Most experiments and introductions of shorter workweeks do not leave the choice of the type/form of reduction up to employees, but to employers. An experiment with a 30-hour workweek in a women’s organisation in Belgium was rather unique in the sense that employees were free to choose how to reduce their working hours on a weekly basis. Based on longitudinal survey and time-diary data as well as in-depth interviews and focus groups, this article investigates what form of working time reduction was preferred by the female employees and what factors influenced these preferences. The life course perspective is taken as a lens through which we analyse women’s preferences and choices. Results show that there was a clear preference for having one day off per week instead of shorter daily hours. This choice was mostly related to meso-factors concerning work and private circumstances and is not fixed but rather dynamic.
Making Holocaust Memory in Finland: The Jewish Community and Conflicting Loyalties, 1944–1950s
Authors: Muir Simo 
Published: December 2023

Abstract
This article analyzes how Finnish Jews defined their position during the Second World War when Finland fought against the Soviet Union as a co-belligerent of Nazi Germany. After the Moscow Armistice in September 1944, the Jewish community’s leadership created an official narrative that transformed the community’s travails into a positive experience. They wanted to signal to the Allied forces and Jewish communities worldwide that their rights had not been violated during the war, even though Finland had been de facto allied with Nazi Germany. By doing so, they suppressed knowledge of the treatment of Jewish refugees and their deportations, as well as of their own volatile positions during the war. By inviting Marshal Mannerheim to the Helsinki synagogue in December 1944, the community helped forge Mannerheim into a national hero by honoring him for saving the Finnish Jewish community from the Holocaust. In addition, this article examines how Finnish Jews commemorated Holocaust victims vis-à-vis the commemoration of fallen Jewish soldiers in the transnational Jewish (survivor) community in the immediate postwar years.
‘Follow the cattle’: a joint cross-border trachoma MDA perspective
Authors: Baayenda Gilbert , Opon Raphael , Waititu Titus , Kabona George 
Published: December 2023

Abstract
Trachoma, a disease caused by Chlamydia trachomatis, is the leading infectious cause of blindness. To fight it, endemic East African countries adopted the World Health Organization’s SAFE Strategy, targeting surgery, antibiotics through mass drug administration (MDA), facial cleanliness and environmental improvement. Trachoma persists among nomadic communities along the Kenya–Uganda and Kenya–Tanzania borders. To address this, Kenya, Tanzania and Uganda launched synchronized MDA campaigns, simultaneously treating populations across borders. Successes included joint planning, community involvement and intergovernmental cooperation, although challenges remained in resourcing MDA cross-border focal points and in addressing coverage and funding. Novel strategies like synchronized joint cross-border MDA with community engagement are vital for sustainable trachoma elimination in these nomadic settings.
Amino acid standardized ileal digestibility together with concentrations of digestible and metabolizable energy in Saccharomyces cerevisiae yeast and soybean meal for gestating sows
Authors: Zhao Yang , Lin Yan , Xu Shengyu , Hua Lun , Feng Bin , Fang Zhengfeng , Jiang Xuemei , Che Lianqiang , Zhuo Yong , Wu De 
Published: December 2023

Abstract
The standardized ileal digestibility (SID) of amino acids (AAs) plus crude protein (CP), in addition to digestible energy (DE) and metabolizable energy (ME) concentrations, was assessed through two experiments on Saccharomyces cerevisiae yeast (SCY) combined with soybean meal (SBM) for gestating sows. SCY and SBM were subjected to experiment 1 for the determination of CP and AAs in terms of SID. Under a randomized complete block design, three dietary treatments were provided for a total of 24 Landrace × Yorkshire gestating sows (parity 2), with the distal ileum clipped by a T-cannula at gestational day 33 based on body weight (BW) (194.1 ± 7.1, 195.3 ± 8.5, and 195.3 ± 8.6 kg). SCY and SBM were used as the only source of nitrogen to prepare two semi-purified diets and a nitrogen-free diet was also utilized to examine CP plus AAs for basal ileal endogenous losses. The gestating sows were initially fed these diets for 5 d to allow for adaptation, and ileal digesta was collected 2 d later for analysis. CP and all AAs in SCY, except for Trp and Gly, showed significantly lower SID than those in SBM (P &lt; 0.05). Among the essential AAs, the range of SID was 68.8% for Thr to 92.2% for Arg in dried yeast, and from 79.9% for Thr to 98.6% for Met in SBM. DE plus ME were measured via experiment 2 with a randomized complete block design on SCY and SBM. Eighteen day-35 Landrace × Yorkshire pregnant sows (parity 3) were allocated to three diets based on BW (233.3 ± 16.0, 233.4 ± 9.6, and 233.4 ± 10.3 kg). Three diets were adopted for the experiment, namely, a corn-based diet as well as two diets containing 20.2% SCY and 20.0% SBM samples. The full fecal collection method, comprising a 5-day adaptation period before a 5- to 6-d experimental period for quantitative urine and feces collection, was employed for metabolic trials. The DE and ME for SCY were remarkably decreased compared with those for SBM (3812 kcal/kg DM vs. 4264 kcal/kg DM and 3714 kcal/kg DM vs. 4157 kcal/kg DM), respectively (P &lt; 0.05). No differences were observed in the apparent total tract digestibility (ATTD) of organic matter, CP, and gross energy between SCY and SBM, but ATTD was significantly reduced in SCY for acid detergent fiber, dry matter, and neutral detergent fiber by contrast with SBM (P &lt; 0.05). In conclusion, most AAs and CP in SCY had lower SID, DE, and ME than SBM in this study. These findings can be applied to diet formulation with the aforementioned ingredients for sows.
Revision of the Strodei Subgroup of Nyssorhynchus (Diptera: Culicidae), with descriptions of 2 new species
Authors: Sant’Ana Denise Cristina , Sallum Maria Anice Mureb 
Published: December 2023

Abstract
Nyssorhynchus (Nyssorhynchus) ibiapabaensis (Sant'Ana & Sallum n. sp.) and Ny. (Nys.) untii (Sant'Ana & Sallum n. sp.) are new species of the Arthuri Complex of the Strodei Subgroup. The new species are described and validated using morphological characters of the male, female, and immature stages. The description of the male, female, fourth-instar larva and pupa of Ny. arthuri (Unti, 1941) and Ny. albertoi (Unti, 1941) are provided for the first time. To avoid nomenclature instability, neotypes are designated for both species. All life stages of Ny. strodei (Root, 1926) employing specimens collected in the Agua Limpa District, Juiz de Fora, Minas Gerais, Brazil are redescribed.