bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Cretaceous deposits of the Paris Basin
Authors: Amédro Francis , Deconinck Jean-François , Robaszynski Francis 
Published: November 2023

Abstract
Since the creation of the Cretaceous system by Jean-Baptiste d'Omalius d'Halloy, numerous analyses have provided details about the Cretaceous sedimentary successions of the Paris Basin, where many boreholes have been drilled. We present a synthesis of the Cretaceous deposits using data from recent drilling carried out in the central and eastern parts of the basin which, during the early Cretaceous, corresponded to a continental environment represented by Wealden facies. However, from the Berriasian to the Barremian, the southeastern part of the basin was occasionally invaded by a shallow sea during transgressions originating from the Tethys Ocean. The sedimentary successions of this age presented in this article have been studied thanks to drilling carried out by Andra (French Agency for Nuclear Waste Disposal). Several new results are presented here: a discussion on the age of the Argiles ostréennes, the identification of an equivalent of oceanic anoxic event (OAE)1a, and the construction of a continuous section of the Albian clays in their type area. Regarding the Upper Cretaceous chalk, the Cenomanian to Maastrichtian stages are represented over the entire basin and correlations are proposed based on biostratigraphic data and various marker beds including marly levels, bentonites, hardgrounds and eco-events.
New approaches to an old problem: addressing spatial gaps in the World Stress Map
Authors: Coblentz D. , van Wijk J. , Carmichael J. , Johnson C. , Delorey A. , Chai C. , Maceira M. , Richardson R. M. 
Published: November 2023

Abstract

A well-recognized characteristic of the World Stress Map (WSM) database is the continued presence of large spatial gaps in the distribution of the data records despite the more than 40-year development history of the database. The current release has more than 30 000 high-quality (A–C) data records (often referred to as ‘stress indicators’), but while some continental areas (such as Australia) have seen a significant increase in spatial converge with the latest release, other continental regions (Africa, central Asia, most of South America) remain markedly sparse. In this contribution we (1) review the current state of the spatial distribution of stress indicators in the continental regions (above sea-level); (2) quantify the clustering of the stress indicators in the latest WSM release using the Hopkins statistic as a way to explore the current spatial distribution of the indicators and assess future WSM releases; and (3) present three approaches (joint inversion, seismic anisotropy and InSAR) that provide a way to fill in the gaps (both in the S
Hmax
orientation and principal stress magnitudes) in regions that lack active seismicity and where borehole drilling is cost prohibitive. These three approaches have the potential to guide procedures for improving
a priori
estimates of the ambient stress field in the Earth's crust and reduce the uncertainty in predicting both the magnitude and orientation of the principal tectonic stresses.
Variations in the Urinary Iodine Concentration and Urinary Iodine/Creatinine Ratio among Preschool Children
Authors: An Dong , Yang Rui , Du Yuping , Wang Xuan , Yang Ying , Guo Wenxing , Yang Junhong , Meng Dongmei , Gao Weiwei , Zhang Jiayi , Chen Wen , Zhang Wanqi 
Published: November 2023

Variations in different urinary measurements for evaluating iodine status are concerning to clinicians and researchers. The present study aimed to analyze the interindividual and intraindividual variations in the urinary iodine concentration (UIC) and urinary iodine/creatinine (UI/Cr) ratio and evaluate their application in assessing the iodine nutrition of preschool children. Four repeated spot urine samples were collected from 163 children at different times within one day. The urinary iodine concentration (UIC) and urinary creatinine concentration (UCr) were measured, and the UI/Cr ratio was calculated. The UIC (

P

< 0.001) and urinary iodine/creatinine ratio (

P

= 0.019) of multiple measurements were significantly different. The UIC of morning urine was highest (99.83 μg/L) and then gradually decreased with collection time (

P

< 0.001). In contrast, the UI/Cr ratio of morning urine samples increased with collection time. By computing the mean intraindividual and interindividual coefficients of variance (CV), the intraindividual variation of the UI/Cr ratio (68%) was significantly lower than that of the UIC (86%). Nevertheless, the interindividual variation was lowest in the UIC (78.62%) of morning urine. In addition, the UIC and UI/Cr ratio showed moderate correlations (r = 0.52,

P

< 0.001), with kappa values of 0.42 in assessing iodine nutrition. The UIC of morning urine samples taken at 8:00–10:00 am was perhaps more stable and reliable in evaluating the iodine nutrition of preschool children at the population level. The UI/Cr ratio showed lower intraindividual variation and may be more suitable for assessing individual iodine nutrition.
PUMA/RIP3 Mediates Chemotherapy Response via Necroptosis and Local Immune Activation in Colorectal Cancer
Authors: Chen Dongshi , Ermine Kaylee , Wang Yi-Jun , Chen Xiaojun , Lu Xinyan , Wang Peng , Beer-Stolz Donna , Yu Jian , Zhang Lin 
Published: November 2023

Abstract
Induction of programmed cell death (PCD) is a key cytotoxic effect of anticancer therapies. PCD is not confined to caspase-dependent apoptosis, but includes necroptosis, a regulated form of necrotic cell death controlled by receptor-interacting protein (RIP) kinases 1 and 3, and mixed lineage kinase domain-like (MLKL) pseudokinase. Necroptosis functions as a defense mechanism against oncogenic mutations and pathogens and can be induced by a variety of anticancer agents. However, the functional role and regulatory mechanisms of necroptosis in anticancer therapy are poorly understood. In this study, we found that RIP3-dependent but RIP1-independent necroptosis is engaged by 5-fluorouracil (5-FU) and other widely used antimetabolite drugs, and functions as a major mode of cell death in a subset of colorectal cancer cells that express RIP3. We identified a novel 5-FU–induced necroptosis pathway involving p53-mediated induction of the BH3-only Bcl-2 family protein, p53 upregulated modulator of apoptosis (PUMA), which promotes cytosolic release of mitochondrial DNA and stimulates its sensor z-DNA-binding protein 1 (ZBP1) to activate RIP3. PUMA/RIP3-dependent necroptosis mediates the in vitro and in vivo antitumor effects of 5-FU and promotes a robust antitumor immune response. Our findings provide a rationale for stimulating necroptosis to enhance tumor cell killing and antitumor immune response leading to improved colorectal cancer treatments.
Validation of the CLARA-A3 Top-of-Atmosphere Radiative Fluxes Climate Data Record
Authors: Akkermans Tom , Clerbaux Nicolas 
Published: November 2023

Abstract
The third edition of the CM SAF Cloud, Albedo and Surface Radiation dataset from AVHRR data (CLARA-A3) contains for the first time the top-of-atmosphere products reflected solar flux (RSF) and outgoing longwave radiation (OLR), which are presented and validated using CERES, HIRS, and ERA5 reference data. The products feature an unprecedented resolution (0.25°) and time span (4 decades) and offer synergy and compatibility with other CLARA-A3 products. The RSF is relatively stable; its bias with respect to (w.r.t.) ERA5 remains mostly within ±2 W m−2. Deviations are predominantly caused by absence of either morning or afternoon satellite, mostly during the first decade. The radiative impact of the Pinatubo volcanic eruption is estimated at 3 W m−2. The OLR is stable w.r.t. ERA5 and HIRS, except during 1979–80. OLR regional uncertainty w.r.t. HIRS is quantified by the mean absolute bias (MAB) and correlates with observation density and time (satellite orbital configuration), which is optimal during 2002–16, with monthly and daily MAB of approximately 1.5 and 3.5 W m−2, respectively. Daily OLR uncertainty is higher (MAB +40%) during periods with only morning or only afternoon observations (1979–87). During the CERES era (2000–20), the OLR uncertainties w.r.t. CERES-EBAF, CERES-SYN, and HIRS are very similar. The RSF uncertainty achieves optimal results during 2002–16 with a monthly MAB w.r.t. CERES-EBAF of ∼2 W m−2 and a daily MAB w.r.t. CERES-SYN of ∼5 W m−2, and it is more sensitive to orbital configuration than is OLR. Overall, validation results are satisfactory for this first release of TOA flux products in the CLARA-A3 portfolio.
Differences Between Consistent and Inconsistent Handedness Remain Consistently Interesting: Ten Years of Research on the Consistency of Handedness With the Edinburgh Handedness Inventory
Authors: Prichard Eric C. , Clarkson Evan M. , Christman Stephen D. 
Published: November 2023

Almost 10 years ago Prichard et al. (2013) published a literature review on consistency of handedness. They described how consistency of handedness, typically measured by the Edinburgh Handedness Inventory (EHI), predicted outcomes in memory and decision-making paradigms better than direction of handedness. In the last 10 years, new research has extended these findings and added new theoretical perspectives. The goal of this short form review is to highlight and summarize some of these more intriguing findings and to encourage researchers in the fields of memory and decision making to incorporate handedness as a variable in future research.
A Machine Learning Workflow to Support the Identification of Subsurface Resource Analogs
Authors: Mabadeje Ademide O. , Salazar Jose J. , Ochoa Jesus , Garland Lean , Pyrcz Michael J. 
Published: November 2023

Identifying subsurface resource analogs from mature subsurface datasets is vital for developing new prospects due to often initial limited or absent information. Traditional methods for selecting these analogs, executed by domain experts, face challenges due to subsurface dataset's high complexity, noise, and dimensionality. This article aims to simplify this process by introducing an objective geostatistics-based machine learning workflow for analog selection. Our innovative workflow offers a systematic and unbiased solution, incorporating a new dissimilarity metric and scoring metrics, group consistency, and pairwise similarity scores. These elements effectively account for spatial and multivariate data relationships, measuring similarities within and between groups in reduced dimensional spaces. Our workflow begins with multidimensional scaling from inferential machine learning, utilizing our dissimilarity metric to obtain data representations in a reduced dimensional space. Following this, density-based spatial clustering of applications with noise identifies analog clusters and spatial analogs in the reduced space. Then, our scoring metrics assist in quantifying and identifying analogous data samples, while providing useful diagnostics for resource exploration. We demonstrate the efficacy of this workflow with wells from the Duvernay Formation and a test scenario incorporating various well types common in unconventional reservoirs, including infill, outlier, sparse, and centered wells. Through this application, we successfully identified and grouped analog clusters of test well samples based on geological properties and cumulative gas production, showcasing the potential of our proposed workflow for practical use in the field.
Differential diagnosis of acute intracranial hemorrhage and calcification by cranial dual-energy computed tomography
Authors: Song Fang , Zhang Faping 
Published: November 2023

Objective To evaluate the application value of dual-energy computed tomography (DECT) in the differential diagnosis of acute intracranial hemorrhage and calcification. Methods This retrospective study involved patients who underwent non-contrast-enhanced cranial DECT in Anhui Wannan Rehabilitation Hospital from January 2015 to November 2022. The processed mixed images obtained after DECT were used as the conventional CT images. Each hyperdense lesion was analyzed based on virtual non-calcium and calcium overlay and classified as calcification or hemorrhage. The sensitivity, specificity, and accuracy of conventional CT and DECT were calculated by the chi-square test according to the unified reference standard. Results Sixty-six hyperdense intracranial lesions of 60 patients were analyzed; of these lesions, 41 (62.12%) were calcifications and 25 (37.88%) were hemorrhages. The sensitivity, specificity, and accuracy of DECT in identifying hemorrhage were 96.00%, 100%, and 98.48%, respectively, while those of conventional CT were 72.00%, 97.56%, and 87.88%, respectively. Of the 66 lesions, 4 (6.06%) could not be qualitatively identified and 3 (4.55%) were misdiagnosed by conventional CT but correctly identified by DECT. Conclusions DECT can accurately distinguish acute intracranial hemorrhage from calcification, especially in cases that are difficult to diagnose by conventional CT.
Suffering for/against the nation: Gharbzadegi and the tensions of anticolonialism in Iran
Authors: Borges Mateus Schneider 
Published: November 2023

What accounts for the nation’s persistence as a central object of identification in anticolonial movements during the 1960s? How can we understand the appeal of nationalism when it simultaneously could signify one path to and a pitfall of decolonisation, as Frantz Fanon warned? This article addresses some of these questions concerning anticolonialism, its political possibilities, decolonial fantasies and desires in Iran. I discuss how Jalal Al-e Ahmad articulated a diagnosis of cultural imperialism, gharbzadegi, that expressed tensions between the translocality to which his framework aspired and the rigid confines of the nation-state model. This imbroglio, I claim, reverberated through the pathologisation of the national group, with the wounds of colonial violence unsettling and reforming different national attachments in Iran. To support this argument, I read the specific conditions, dynamics and sociohistorical processes in which Al-e Ahmad was immersed alongside the transnational structures to which they were related. Juxtaposing this pathological discourse with his travelogues, we can grasp a specific articulation of the translocal-national dyad that informed Al-e Ahmad’s life and found expression in his limited theorisation of gharbzadegi. Analysing this particular context, I argue that this entanglement exposes the limits and pitfalls of anticolonialism in Iran. Souffrir pour/contre la nation : gharbzadegi et les tensions de l’anticolonialisme en Iran
Lowered social motivation is associated with adolescent attention deficit hyperactivity disorder and social anxiety symptoms
Authors: Martin Rachael , McKay Erin , Kirk Hannah 
Published: November 2023

Background Difficulties in social skills are highly prevalent in children and adolescents with attention deficit hyperactivity disorder (ADHD), however, the reasons for these social difficulties are poorly understood. This study aimed to understand social motivation in children (aged 5–8) and adolescents (aged 13–17) with and without ADHD, and the relationship between social anxiety and social motivation in youth with ADHD. Method 204 parents of children and adolescents with and without ADHD completed online questionnaires on social motivation, social anxiety, and ADHD symptoms. Results Adolescents with ADHD had significantly lower social motivation than typically developing adolescents, and children with ADHD. Higher social anxiety significantly predicted lowered social motivation in participants with ADHD. Conclusions These findings indicate a unique pattern of social motivation in ADHD, specifically a reduction during adolescence, reflecting social intervention inefficacy. Additionally, these findings establish a link between social motivation and social anxiety, suggesting that they may act as barriers to social intervention.
A Novel Surgical Technique for Gynecomastia: Air-Assisted Minimally Invasive Surgery With Single Axillary Incision
Authors: Tukenmez Mustafa , Mollavelioglu Baran , Kozanoglu Erol , Emiroglu Selman , Cabioglu Neslihan , Muslumanoglu Mahmut 
Published: November 2023

Background Gynecomastia is a benign condition that develops due to the proliferation of breast tissue in men. Surgical excision is the most effective treatment method. Minimally invasive techniques can be used to avoid visible scarring. We evaluated the efficacy and safety of air-assisted subcutaneous mastectomy in the treatment of gynecomastia. Patient and Methods 10 patients with gynecomastia underwent air-assisted subcutaneous mastectomy and liposuction through a single axillary incision, between June 2022 and February 2023. Demographic and clinical data of the patients, duration of surgery, and complications were recorded. The satisfaction levels of the patients regarding physical appearance, mental status, and social environment were measured. The body Q questionnaire was performed preoperatively and in the postoperative third month. Results The median age was 26 (range, 18-54). Surgical excision was measured as a median of 69 gr (range, 41-177), and liposuction volume was measured as a median of 210 ccs (range, 63-400). The median operation time was 50 minutes (range, 21-60) for excision and 21 minutes (range, 20-75) for liposuction. Body, chest, and nipples related appearance satisfaction levels were measured preoperatively as a median of 44 (range, 36.5-52), 31 (range, 27.5-39), and 51.5 (range, 21-69.8) points vs postoperatively as 92 (range, 92-100), 93 (range, 93-94.8) and 90 (range, 90-100) points, respectively. The patients had a median follow-up of 6 months (range, 3-11). No complications were observed during the follow-up period. Conclusion Air-assisted subcutaneous mastectomy and liposuction is a feasible technique that may provide good cosmetic outcomes by avoiding anterior chest wall scarring.
Associations between menopause and body image: A systematic review
Authors: Vincent Coralie , Bodnaruc Alexandra M , Prud’homme Denis , Olson Viviane , Giroux Isabelle 
Published: November 2023

Background: The menopausal transition involves multiple biological and psychosocial challenges that may render middle-aged women vulnerable to body image concerns. Objective: The aim of this study was to summarize evidence on the associations between menopause and body image perception in healthy middle-aged women. Design: This study is a systematic review of observational studies. Data sources and methods: Menopause-related exposure measures included menopausal stages, menopausal symptoms, and reproductive hormone levels during the menopausal transition. Studies investigating body image as an outcome, including through a positive (e.g. body self-esteem) or negative (e.g. body dissatisfaction) lens, were considered eligible. Articles published before March 2023 were identified through MEDLINE, PsycINFO, and Embase and underwent double screening, extraction, and quality assessment by two independent investigators. Characteristics and results were summarized using narrative synthesis. Results: A total of 820 non-duplicate records were identified, with 18 observational studies deemed eligible for inclusion after full-text screening. All studies investigating menopausal symptoms and body image ( n = 6) found some significant association between them, with a higher frequency, intensity, or number of symptoms being associated with greater body image concern. Differences in body image perception between menopausal stages were inconsistent across studies ( n = 12), while evidence of potential associations between reproductive hormones and body image was minimal ( n = 2). Findings should be interpreted with caution as 17 of the included studies used a cross-sectional design, and not all studies adjusted their analyses for relevant confounders. Conclusion: Overall, menopausal symptoms showed relatively consistent associations with a more negative body image perception. Additional research is required to understand the potential role of menopausal stages and reproductive hormone levels in the body image perception of middle-aged women and to confirm the direction of reported associations. Registration: PROSPERO—CRD42021241637
Treatment of unstable pelvic fractures in children with an external fixator: Retrospective study of 56 patients
Authors: Wen Yuwei , Zhu Danjiang , Wang Qiang , Song Baojian , Feng Wei 
Published: November 2023

Purpose: We retrospectively analyzed the data of patients who underwent external fixation treatment for unstable pelvic fractures and evaluated the clinical effects of this treatment and factors influencing pelvic function recovery. Methods: The data of patients with unstable pelvic fractures treated with an external fixator between January 2006 and December 2018 were retrospectively analyzed. The analyzed parameters included demographic data, fracture healing, pelvic asymmetry, deformity index, and complications. Fractures were categorized using the Tiles classification. Pelvic function was evaluated using the Cole score. Pelvic risk factors were identified using univariate and multivariate logistic regression analyses. Results: Fifty-six patients (29 and 27 with type B and C fractures, respectively) were included. All fractures were healed at the time of the final follow-up. Nine and three patients had pin tract infections and loosened external fixators postoperatively, respectively. Pelvic asymmetry was reduced from 1.34 ± 0.15 cm to 0.70 ± 0.19 cm (p < 0.01), and the deformity index decreased from 0.13 ± 0.03 to 0.07 ± 0.02 (p < 0.01). The Cole score was excellent and good in 41 and 15 patients, respectively. Risk factors for pelvic function recovery included injury severity score > 25.5, age > 11.3 years, and lower-extremity fractures. Conclusions: External fixation is an effective method for treating unstable pelvic fractures in children, with the advantages of a simple operation, short surgical time, no interference with treatments for associated injuries, and avoidance of re-trauma caused by open reduction. An ISS > 25.5, patient age > 11.3 years, and associated lower-extremity fractures are predictors of pelvic function recovery. Level of evidence: Level IV.