bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Metal‐Free Helical Covalent Inorganic Polymer: Preparation, Crystal Structure and Optical Properties
Authors: Xue Miaomiao , Zhang Lei , Wang Xiang , Dong Qiang , Zhu Zengkui , Wang Xin , Gu Qianfeng , Kang Fangyuan , Li Xin‐Xiong , Zhang Qichun 
Published: December 2023

AbstractHelical morphologies are widely observed in nature, however, it is very challenging to prepare artificial helical polymers. Especially, precisely understanding the structure information of artificial metal‐free helical covalent inorganic polymers via single‐crystal X‐ray diffraction (SCXRD) analysis is rarely explored. Here, we successfully prepare a novel metal‐free helical covalent inorganic polymer ({[Te(C6H5)2] [PO3(OH)]}n, named CityU‐10) by introducing angular anions (HOPO32−) into traditional tellurium‐oxygen chains. The dynamic reversibility of the reaction is realized through the introduction of organic tellurium precursor and the slow hydrolysis of polyphosphoric acid. High‐quality and large‐size single crystals of CityU‐10 have been successfully characterized via SCXRD, where the same‐handed helical inorganic polymer chains form a pseudo‐two‐dimensional layer via multiple hydrogen‐bonding interactions. The left‐handed layers and right‐handed layers alternatively stack together through weak hydrogen bonds to form a three‐dimensional supramolecular structure. The single crystals of CityU‐10 are found to display promising optical properties with a large birefringence. Our results would offer new guidelines for designing and preparing new crystalline covalent polymers through tellurium‐based chemistry.
Dynamic Ultra‐long Room Temperature Phosphorescence Enabled by Amorphous Molecular “Triplet Exciton Pump” for Encryption with Temporospatial Resolution
Authors: Deng Huangjun , Li Gaoyu , Xie Haozhi , Yang Zhan , Mao Zhu , Zhao Juan , Yang Zhiyong , Zhang Yi , Chi Zhenguo 
Published: December 2023

AbstractOrganic ultra‐long room‐temperature phosphorescence (RTP) materials in the amorphous state have attracted widespread attention due to their simple preparation and flexibility to adopt various forms in sensors, bioimaging, and encryption applications. However, the amorphous molecular host for the host–guest RTP systems is highly demanded but limited. Here, a universal molecular host (DPOBP−Br) has been designed by integration of an amorphous moiety of diphenylphosphine oxide (DPO) and an intersystem crossing (ISC) group of 4‐bromo‐benzophenone (BP−Br). Various commercial fluorescence dyes were doped into the tight and transparent DPOBP−Br film, respectively, resulting in amorphous host–guest systems with ultra‐long RTP colors from green to red. It was found that DPOBP−Br acted as a universal “triplet exciton pump” for promoting the generation of triplet excitons in the guest, through energy transfer processes and external heavy‐atom effect based on DPOBP−Br. Interestingly, dynamic RTP was achieved by controlling residual oxygen concentration in the amorphous matrix by UV irradiation. Therefore, multi‐dimensional anti‐counterfeiting coatings were realized even on curved surfaces, simultaneously exhibiting spatial and 2D‐time dependence. This work provides a strategy to design new amorphous molecular hosts for RTP systems and demonstrates the advanced information encryption with tempo‐spatial resolution based on the dynamic ultra‐long RTP of an amorphous system.
In conversation: transgenerational attachment trauma, the infant, and the family therapist
Authors: McIntosh Jennifer , Newman Louise , George Carol 
Published: December 2023

AbstractThis paper shares a far‐ranging set of conversations between professors Jennifer McIntosh, Louise Newman, and Carol George, all child and family practitioners, and infant mental health (IMH) and attachment specialists. They explore the domain of infant–family work with high‐risk populations experiencing complex relational and intergenerational trauma. George and McIntosh discuss the intersection between family therapy and IMH from an attachment perspective. They explore what family therapy can offer to supporting coherence in caregiving states of mind, beyond the offerings of traditional dyadic mother–baby models of intervention. They highlight the infant's contribution to family work, and the application of attachment theory in a family therapy context. Newman and McIntosh discuss a sensitive and graded approach to high‐risk family work with an infant. Newman reflects on when and whom to invite to a family session and the power of enabling the family to speak the unspeakable in the presence of the baby, supporting a future focused path for trauma integration and recovery. For family therapists who may be new to IMH work, there are some important offerings about integrating these fields, bringing into play the family therapist's deep grasp of curiosity, circularity, and capacity to reconceptualise with an IMH perspective on early relational trauma.
Comparative aspects on the epoxidation of soybean oil and high oleic soybean oil
Authors: de Quadros Jacyr Vianna , Ferreira Luiz Felipe Silva , Olivieri Gustavo Vieira , Karis Dylan , Giudici Reinaldo 
Published: December 2023

AbstractSoybean oil (SO) epoxidation is an extensively studied method to generate a sustainable plasticizer for polyvinyl chloride (PVC). Standard soybean oil is composed of triglycerides whose fatty acids are primarily unsaturated linoleic, oleic, and linolenic acids. High oleic soybean oil (HOSO) is collected from a soybean variety higher in oleic acid than other acids. The present study focused on a preliminary comparison of the epoxidation reaction behavior between SO and HOSO, conducted isoperibolically and without catalysts. The experimental data were modeled by a kinetic model. Considerable differences in the temperature and oxirane index profiles suggest that the epoxidation of HOSO tends to be faster and with a more intense heat release rate than the epoxidation of SO, which was confirmed by the results of estimated kinetic constants. The data collected and shared herein suggest that a first epoxy group generated may cause steric hindrance to slow the epoxidation in the second and third double bonds of the oil.
Rare earth element stripping from kaolin sands via mild acid treatment
Authors: Koch Max , Paper Michael , Brück Thomas B. , Nilges Tom 
Published: December 2023

AbstractDue to their chemical and physical properties, rare earth elements (REEs) are essential in modern applications such as energy conversion or IT technology. The increasing demand for these elements leads to strong incentives for REE recovery and induces the exploration of new, alternative sources for REEs. Accessing REEs from clay minerals, in our case kaolinite, by an elution process is a promising method. The present study investigates the potential application of REE recovery through elution with different mineral acids (HNO3, H2SO4, and HCl) in a microwave process. The material used in this study—residues from an industrial kaolin production process—contained 2.47 g/kg REEs which is a significant amount for REE recovery. The ability of various mineral acids to solubilize metals was studied to assess the REE content of this residual resource. Around 1.87 g/kg of REEs was eluted from industrial kaolinite residues in hydrochloric acid, 1.71 g/kg in sulfuric acid, and 1.13 g/kg in nitric acid.
Stability assessment of a commercial polypropylene copolymer and Irgafos 168 under repeated injection molding and γ‐irradiation cycles
Authors: Zerhusen Nele , Herrmann Susanna , Susoff Markus Lothar , Petersen Svea 
Published: December 2023

AbstractDespite the increasing importance of recycling, the medical sector is hardy engaged at this time due to regulatory issues. The aim of this study was to evaluate the influence of γ‐radiation sterilization (48–52 kGy) on the repetitive injection molding of a polypropylene copolymer for medical applications. For this purpose, the material was analyzed after injection molding and irradiation. To evaluate the irradiation and reprocessing influence, optical, rheological, and mechanical properties were investigated in addition to chromatography. The latter comprised the quantitative determination of Irgafos 168 and the qualitative comparison of volatile degradation products formed, including the radiolysis product 1,3‐di‐tert‐butylbenzene. The influence of irradiation on the content of Irgafos 168, volatile organic compounds, and 1,3‐di‐tert‐butylbenzene was greatest after the first irradiation, with a decrease of Irgafos 168 content by 40%. The yellowness index and melting enthalpy were influenced by irradiation and processing, but showed no direct relationship to the individual process steps. The zero viscosity correlated directly with gas chromatography–mass spectrometry results and decreased by 80% after the first irradiation. In addition, the elongation at break was reduced by 95% after the second irradiation. The influence of irradiation on the studied characteristics was high, whereas the influence of repetitive processing did not show any measurable differences
Human dissection for anesthesiology resident training augments anatomical knowledge and clinical skills
Authors: Maffucci Patrick , Park Chang H. , Shirur Mo , Hyers Benjamin , Levine Adam I. , Katz Daniel , Burnett Garrett W. , Laitman Jeffrey T. 
Published: December 2023

AbstractAnatomy is an essential component of clinical anesthesiology. The use of simulated patients and alternative materials, including embalmed human bodies, have become increasingly common during resident physician training due to the deemphasis on anatomical education during undergraduate medical training. In this report, the need for a more extensive review of relevant anatomy for the practice of anesthesiology was addressed by the design, evaluation, and dissemination of a human dissection course for procedural training of anesthesiology residents. The course utilized “freedom art” embalmed human bodies that allowed trainees to perform ultrasound‐based regional and neuraxial techniques followed by detailed dissections of critical anatomy. One hundred and four residents participated in workshops and small group discussions and were evaluated using pre‐ and post‐course assessments. A variety of clinical techniques were performed on the bodies, including regional blocks and neuraxial catheter placement. Insertion of peripheral/neuraxial catheters was successful, with dissections demonstrating the expected placement. Assessment scores improved following the course (pre‐course mean 52.7%, standard deviation (σ) 13.1%; post‐course mean 72.2%, σ 11.6%; t‐test p < 0.0001) and feedback highlighted the usefulness and clinical relevance of course content. The ability to correlate ultrasound imaging with subsequent dissections of the “blocked” area and visualization of dye staining was extremely relevant for spatial understanding of the anatomy relevant for the clinical practice of these techniques. This manuscript demonstrates successful implementation of a comprehensive course for anesthesiology resident physicians to address gaps in undergraduate anatomical education and suggests that broader adoption of dissection courses may be beneficial for training anesthesiologists.
Das γ‐Verfahren zur Berechnung nachgiebig verbundener Biegeträger: allgemeine Methode
Authors: Zhu Jianzhong 
Published: December 2023

AbstractVon grundlegender Bedeutung für die Berechnung nachgiebig verbundener Biegeträger ist das sog. γ‐Verfahren. In diesem Beitrag werden die Grundlagen und die exakten Lösungen für das γ‐Verfahren ausgearbeitet. Das in der deutschen und europäischen Holzbau‐Normung zur Berechnung nachgiebig verbundener Biegeträger mit maximal drei Einzelquerschnitten verankerte Verfahren wird auf Biegeträger mit beliebig vielen Einzelquerschnitten erweitert.
Ökobilanzierung im Bauwesen
Authors: Hauke Bernhard , Hein Helen Luisa 
Published: December 2023

AbstractSeit mindestens 15 Jahren gibt es in Deutschland praktische Erfahrungen mit der Ökobilanzierung im Bauwesen, zuerst im Kontext von Nachhaltigkeitszertifizierungen, inzwischen zunehmend auch als Wettbewerbs‐ und Fördergrundlage. Nur was messbar ist, kann auch gemanagt werden: Mit der Ökobilanzierung werden die im Lebenszyklus auftretenden Energie‐ und Stoffströme sowie unerwünschte Wirkungen auf die Umwelt erfasst. Ziele sind u. a. die Schonung primärer Rohstoffe sowie der Schutz des Ökosystems und des Klimas. Aktuell nimmt das Interesse an der Ökobilanzierung zu. Im Fokus steht dabei insbesondere das Treibhauspotenzial. So ist eine Ökobilanz Grundlage für den Nachweis der Begrenzung der nicht erneuerbaren Primärenergie und des Treibhauspotenzials für das Qualitätssiegel Nachhaltiges Gebäude (QNG) als Fördervoraussetzung. Die Einführung von Grenzwerten ins Ordnungsrecht wird diskutiert.
Fertigteilüberbauten für Brücken aus Hochfestem Beton – schneller, schlanker und nachhaltiger
Authors: Haveresch Karlheinz , Maurer Reinhard , Breitenbücher Rolf 
Published: December 2023

AbstractFür mehr Tempo bei der dringenden Brückenmodernisierung im deutschen Straßen‐ und Schienennetz ist es erforderlich, auch die Bautechnik für Brücken zu modernisieren. Die neuen Brücken sollen möglichst schnell gebaut werden können und schön, nachhaltig und robust sein. Es zeigt sich, dass Fertigteilbauweisen für dieses Anforderungsprofil besonders vorteilhaft sein können. Die Chancen, die diese Bauweise bietet, sollen daher zukünftig verstärkt genutzt werden. Als besonders leistungsfähige Innovation erweist sich die neue Option, Fertigteile mit Hochfestem Beton einzusetzen. Damit kann der Anwendungsbereich für Brückenüberbauten aus Betonfertigteilen erheblich ausgeweitet und den Anforderungen der Brückenmodernisierung angepasst werden. Die vorliegenden Langzeiterfahrungen mit Brücken aus Hochfestem Beton lassen außerdem eine hervorragende Dauerhaftigkeit und Nachhaltigkeit dieser Tragwerke erwarten.
Integration of lipidomics and metabolomics reveals plasma and urinary profiles associated with pediatric Mycoplasma pneumoniae infections and its severity
Authors: Chen Hui , Chen Jia‐bin , Du Li‐na , Yuan Hai‐xia , Shan Jin‐jun , Wang Shou‐chuan , Ye Jin , Lin Li‐li 
Published: December 2023

AbstractMycoplasma pneumoniae is a significant contributor to lower respiratory infections in children. However, the lipidomics and metabolics bases of childhood M. pneumoniae infections remain unclear. In this study, lipidomics and metabolomics analyses were conducted using UHPLC‐LTQ‐Orbitrap XL mass spectrometry and gas chromatography‐triple quadrupole mass spectrometry on plasma (n = 65) and urine (n = 65) samples. MS‐DIAL software, in combination with LipidBlast and Fiehn BinBase DB, identified 163 lipids and 104 metabolites in plasma samples, as well as 208 metabolites in urine samples. Perturbed lipid species (adjusted p < 0.05) were observed, including lysophosphatidylethanolamines, phosphatidylinositols, phosphatidylcholines, phosphatidylethanol amines, and triglycerides. Additionally, differential metabolites (adjusted p < 0.05) exhibited associations with amino acid metabolism, nucleotide metabolism, and energy metabolism. Thirteen plasma metabolites, namely l‐hydroxyproline, 3‐phosphoglycerate, citric acid, creatine, inosine, ribitol, α tocopherol, cholesterol, cystine, serine, uric acid, tagatose, and glycine, showed significant associations with disease severity (p < 0.05) and exhibited distinct separation patterns in M. pneumoniae–infected bronchitis and pneumonia, with an area under the curve of 0.927. Nine of them exhibited either positive or negative correlations with neutrophil or lymphocyte percentages. These findings indicated significant systemic metabolic shifts in childhood M. pneumoniae infections, offering valuable insights into the associated metabolic alterations and their relationship with disease severity.
Hospital‐ and county‐level characteristics explain geographic variability in prices of cancer‐related procedures: Implications for policy and interventions
Authors: Moss Jennifer L. , Ledford Savanna G. , Bernacchi Veronica , Shen Chan 
Published: December 2023

AbstractBackgroundHealthcare costs in the U.S. are high and variable, which can hinder access and impact health outcomes across communities. This study examined hospital‐ and county‐level characteristics to identify factors that explain geographic variation in prices for four cancer‐related procedures.MethodsData sources included Turquoise Health, which compiles publicly‐available price data from U.S. hospitals. We examined list prices for four procedures: abdominal ultrasound, diagnostic colonoscopy, brain MRI, and pelvis CT scan, which we linked to characteristics of hospitals (e.g., number of beds) and counties (e.g., metropolitan status). We used multilevel linear regression models to assess multivariable relationships between prices and hospital‐ and county‐level characteristics. Supplementary analyses repeated these models using procedures prices for commercial insurance plans.ResultsFor each procedure, list prices varied across counties (intraclass correlation: abdominal ultrasound = 23.2%; colonoscopy = 17.1%; brain MRI = 37.2%; pelvis CT = 50.9%). List prices for each procedure were associated with hospital ownership (all p < 0.001) and percent of population without health insurance (all p < 0.05). For example, list prices for abdominal ultrasound were higher for proprietary versus Government‐owned hospitals (β = 539.10, 95% confidence interval [CI]: 256.12, 822.08, p < 0.001) and for hospitals in counties with more uninsured residents (β = 23.44, 95% CI: 2.55, 44.33, p = 0.03). Commercial insurance prices were negatively associated with metropolitan status.ConclusionsPrices for cancer‐related healthcare procedures varied substantially, with considerable heterogeneity associated with county location as well as county‐level social determinants of health (e.g., health insurance coverage). Interventions and policy changes are needed to alleviate the financial burden of cancer care among patients, including geographic variation in prices for cancer‐related procedures.
Update on the outcome of M‐protein screening program of multiple myeloma in China: A 7‐year cohort study
Authors: Wang Wenjing , Li Jing , Yang Yang , Chen Feifei , Xu Tianhong , Wang Pu , Wang Yawen , Maihemaiti Aziguli , Ren Liang , Lan Tianwei , Li Panpan , Zhou Chi , Liu Peng 
Published: December 2023

AbstractBackgroundTo improve the early detection rate of multiple myeloma (MM), the M‐protein screening system has been performed in the hospital population at Zhongshan Hospital Fudan University since 2014, with electrophoretic‐based monoclonal immunoglobulin (M‐protein) screening integrated into the blood biochemistry panel. This study updated 7‐year follow‐up findings of MM patients diagnosed by screening‐driven and symptom‐driven approaches.MethodsThe retrospective study compared the characteristics and outcomes of patients diagnosed through two patterns by reviewing the plasma cell disease database from January 2014 to October 2021. The screening‐driven group included patients diagnosed through the screening system during workups of unrelated medical conditions or routine checkups. In contrast, patients who visited or were referred to the hematological department due to myeloma‐related end‐organ damage were categorized into the symptom‐driven group.ResultsThere were 3,110,218 serum protein electrophoresis (SPEP) tests performed during 7 years, with 1.95% (60,609) patients yielding positive SPEP results. Of 911 confirmed MM cases (excluding concurrent amyloidosis), 366 were assigned to the screening‐driven group, while 545 were to the symptom‐driven group. Compared to the symptom‐driven group, the screening group had more IgG subtypes, earlier International Stage System stages, fewer disease‐related symptoms, lower ECOG scores, less extramedullary disease, a lower percentage of bone marrow plasma cells, and a lower level of lactate dehydrogenase. Frontline response results of two groups were similar. Patients detected through screening had a significantly improved median progression‐free survival (PFS) than the symptom‐driven group (62.2 vs. 24.9 months, p < 0.001, HR: 2.12, 95% CIs: 1.69–2.65), with median follow‐ups of 32.6 and 27.4 months. Furthermore, the median overall survival (OS) was significantly longer in patients of the screening group (not reached vs. 62.3 months, p < 0.001, HR: 2.49, 95% CIs: 1.81–3.41). After being adjusted for well‐acknowledged myeloma prognostic factors, the screening‐driven diagnostic pattern remained an independent prognostic factor indicating improved PFS and OS in MM patients.ConclusionRoutine M‐protein screening for MM in the hospital population results in an earlier diagnosis and better patient outcomes.
Recent Studies of Nitrogen and Sulfur Containing Heterocyclic Analogues as Novel Antidiabetic Agents: A Review
Authors: Gharge S. , Alegaon S. G. 
Published: December 2023

AbstractThe prevalence of diabetes mellitus is on the rise, which demands the identification of novel antidiabetic drugs. There is a need for safer and more effective alternatives because the therapy methods now available to manage diabetes have limits. Due to their diverse pharmacological characteristics, heterocyclic molecules with nitrogen and Sulfur atoms have become intriguing candidates in medicinal chemistry. These substances have a wide variety of structures that can be customized to target different pathways associated with diabetes and can affect important biological targets involved in glucose homeostasis. This review provides a thorough summary of the most recent studies on heterocyclic analogues of nitrogen and Sulfur as prospective antidiabetic agents. This review examines the variety of their structural forms, their methods of action, and assesses the results of preclinical and clinical investigations on their effectiveness and safety. Additionally, further optimization and development of innovative antidiabetic medications are highlighted, as well as the difficulties and prospects for the future in utilizing the therapeutic potential of these analogues. This study seeks to stimulate additional investigation and cooperation between researchers and medicinal chemists, promoting improvements in the creation of efficient and secure antidiabetic medicines to fulfill the needs in the management of diabetes.
Successful re‐implantation of eroded penile prostheses: Report of two cases and review of the literature
Authors: Basiri Abbas , Zahir Mazyar 
Published: December 2023

Key Clinical MessagePrompt removal of eroded penile prostheses is recommended in most cases. However, saving and reimplanting eroded implants may be considered in patients without signs of sepsis, local infection or necrosis during preoperative evaluations and surgical exploration. Notably, close postoperative surveillance is crucial in this setting.