bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effects of aerobic exercise on goal-directed attention and inhibitory control in individuals with high trait anxiety: an EEG study
Authors: He Mengyang , Guo Jinxia , Yu Shunyao , Lian Hao , Zhan Ruijie , Luo Rongrong , Shi Zhifei , Zhuang Zhidong , Cai Wenpeng 
Published: January 2025

Abstract
Anxiety is known to significantly impair cognitive function, particularly attentional control. While exercise has been demonstrated to alleviate these cognitive deficits, the precise neural mechanisms underlying these effects remain poorly understood. This study examines the effects of exercise on attentional control in individuals with high trait anxiety, based on attentional control theory, which suggests that such individuals have reduced top-down attention. Thirty-eight participants were randomly assigned to either an exercise group or a reading group. The exercise group engaged in 30 min of moderate-intensity cycling, while the reading group spent 30 min reading quietly. In Experiment 1, goal-directed attention was assessed using a cue-object paradigm, and in Experiment 2, inhibitory control was evaluated through a visual search task. EEG data indicated that the exercise group exhibited significantly larger Pd components in both experiments, suggesting enhanced attentional focus and improved inhibition of distractors. These findings suggest that aerobic exercise enhances top-down attentional processes, particularly goal-directed attention and distractor inhibition, offering potential as an intervention for individuals with high trait anxiety.
Enhanced high-energy proton radiation hardness of ZnO thin-film transistors with a passivation layer
Authors: Lee Yongsu , Lee Hae-Won , Kim Su Jin , Park Jeong Min , Lee Byoung Hun , Kang Chang Goo 
Published: January 2025

Abstract
Metal-oxide thin-film semiconductors have been highlighted as next-generation space semiconductors owing to their excellent radiation hardness based on their dimensional advantages of very low thickness and insensitivity to crystal structure. However, thin-film transistors (TFTs) do not exhibit intrinsic radiation hardness owing to the chemical reactions at the interface exposed to ambient air. In this study, significantly enhanced radiation hardness of Al2O3-passivated ZnO TFTs against high-energy protons with energies of up to 100 MeV is obtained owing to the passivation layer blocking interactions with external reactants, thereby maintaining the chemical stability of the thin-film semiconductor. These results highlight the potential of passivated metal-oxide thin films for developing reliable radiation-hardened semiconductor devices that can be used in harsh space environments. In addition, the relationship between low-frequency noise and defects due to oxygen vacancies was revealed, which can be utilized to improve device reliability.
Complexity of near-surface deformation and subsurface structure of the Chihshang creeping fault-line scarp, eastern Taiwan: insights from integration of geological and geophysical data
Authors: Huang W. J. , Fitrianto M. T. , Chen C. C. , Chang P. Y. , Yen I. C. , Le Béon M. , Lu S. T. 
Published: January 2025

Abstract
The precise position and geometry of a fault and the recognition of contemporary active strands are pivotal elements for formulating regulations for earthquake fault zones and fault setbacks. The western frontal escarpment toe of the Coastal Range in Tapo, eastern Taiwan is commonly considered as the plausible location of the N18°E-trending, east-dipping Chihshang creeping seismogenic fault. Frontal collapse and flattening of reverse faulting, in addition to fluviation and landslide have complicated the process for defining the Chihshang fault configuration. We used a multidisciplinary approach, combining site investigation, geological core analysis and correlation, resistivity prospecting, and inclinometer monitoring, to illuminate the subsurface structure and deformation of the leading edge of the Chihshang fault at Tapo Elementary School. We found that (1) the Chihshang main fault is a contact of alluvium deposits and the mudstone of Lichi mélange, and has a dip angle of approximately 77° within the resistivity gradation zone 55 m east of the toe of the geomorphic escarpment; (2) it has a 2-year cumulative horizontal displacement of 20.7 mm northwestward and continuously creeps without seasonal variation; and (3) the active deformation on the escarpment results from a combined effect of fault creeping and slow gravity sliding of the mass which is steadily supplied by the Chihshang reserve faulting. A mechanism of faulting-relay landsliding is proposed to understand the active deformation on the escarpment. Great caution is needed in the interpretation of the aseismic surface ruptures along the inferred trace of reverse creeping faults as fault branching.

Graphical Abstract
Flexible and wireless metasurface coils for knee and elbow MRI
Authors: Düx Daniel M. , Kowal Robert , Knull Lucas , Schröer Simon , Belker Othmar , Horstmann Dominik , Gutt Moritz , Maune Holger , Speck Oliver , Wacker Frank , Hensen Bennet , Gutberlet Marcel 
Published: January 2025

Abstract

Background
Metasurface coils (MCs) are a promising magnetic resonance imaging (MRI) technology. Aiming to evaluate the image quality of MCs for knee and elbow imaging, we compared signal-to-noise ratio (SNRs) obtained in standard clinical setups.

Methods
Knee and elbow MRI routine sequences were applied at 1.5 T, implementing four coil scenarios: (1) 15-channel transmit/receive knee coil; (2) four-channel multipurpose coil (flex coil); (3) MC + spine coil; and (4) MC + multipurpose coil. Three regions of interest (ROIs) at different anatomical depths were compared.

Results
Seven participants (aged 28 ± 2 years; 6 males) were enrolled. In elbow MRI, the MC + spine coil demonstrated the highest SNR across all ROIs (superficial-anterior: +114%, p = 0.008; middle: +147%, p = 0.008; deep-posterior: +24%, p = 0.039) compared to the flex coil and all ROIs, except the deepest from the MC, compared to the knee coil (superficial-anterior: +28%, p = 0.016; middle: +104%, p = 0.008; deep-posterior: −1%, p = 0.531). In knee MRI, the MC + spine coil provided higher SNR compared to the flex coil, except posterior (superficial-anterior: +69%, p = 0.008; middle: +288%, p = 0.008; deep-posterior: −12%, p = 0.148) versus the knee coil, the MC + spine coil was superior in the middle but non-different in superficial pre-patellar areas and less in deep-posterior areas (superficial-anterior: −8%, p = 0.188; middle: +44%, p = 0.008; deep-posterior: −36%, p = 0.016).

Conclusion
Wireless MCs exhibited great potential for knee and elbow MRI outperforming the flex coil. Future developments will improve the posterior illumination to increase its clinical value.

Relevance statement
MCs offer enhanced versatility, flexibility, and patient comfort. If universal MC designs can achieve image quality comparable to those of standard coils and simultaneously be utilized across multiple body areas, the technology may revolutionize future musculoskeletal MRIs.

Key Points

MCs are promising in MRI, but homogeneity is challenging depending on the design.

Signal-to-noise-ratio was improved for knee and elbow imaging with slight inhomogeneous illumination.

MCs could match the image quality of standard coils in both knee and elbow imaging.

Graphical Abstract
Short-term outcome of endovascular stenting for symptomatic vertebrobasilar stenosis
Authors: Tolba Mohamed Abdel moneim Abdo , Alaswad Mohammed , Tawfik Mohamed Mohamed , Akl Ahmed Zaki , Eissa Mona Ali , El-khawas Hala , Eldin Hani Mahmoud Zaki , Elewa Mohamed Khaled Ahmed 
Published: January 2025

Abstract

Background
Stroke is a global health concern, causing blood supply interruption to the brain. Vertebrobasilar stenosis (VBS) is the main concern, causing stroke or ischemic attacks. Treatment includes antithrombotic therapy and lifestyle modifications, but invasive intervention like endovascular angioplasty is needed in indicated patients. This study aims to investigate the short-term outcome of endovascular stenting, especially, drug-eluting stents (DES) for symptomatic vertebrobasilar stenosis. In this prospective cohort study, we selected patients with ischemic events, including transient ischemic attack (TIA) or non-disabling stroke, diagnosed by CT or MRI brain, MRA, and over 70% diameter stenosis of the basilar or vertebral artery suggested by angiography. Patients with previous stent at the target lesion, acute stroke, heavily calcified lesion, complete artery occlusion, massive infarction with marked neurological deficit, intracranial hemorrhage, intracranial brain tumors, contraindicated to antithrombotic and/or anticoagulant, pregnant women, and patients susceptible to follow-up loss were excluded.

Results
This study involved 17 patients evaluated for ischemic events in the vertebrobasilar system, with a mean age of 58.47 ± 9.41 years. The most prevalent comorbidity was a previous transient ischemic attack (TIA) in 15 patients (88.2%), followed by hypertension in 12 patients (70.6%), diabetes and hyperlipidemia in 10 patients each (58.8% for both). Ischemic heart disease was present in 6 patients (35.3%), and smoking was reported by 5 patients (29.4%). The predominant stenosis location was intracranial in 11 patients (64.7%), with extracranial being the second most prevalent site in 6 patients (35.3%). The most prevalent kind of stenosis observed was atherosclerosis, affecting 11 patients (64.7%), followed by dissection in 6 patients (35.2%). The peri-procedural outcomes were good in 15 patients (88.2%) and bad in 2 patients (11.8%). The modified Rankin score (MRS) score was significantly decreased after 5-month follow-up than pre-operative. There was no statistically significant difference between extracranial and intracranial stenosis regarding the final outcome, residual stenosis, or peri-procedural complications.

Conclusions
Our findings emphasize the potential advantages of stenting for carefully chosen individuals with symptomatic vertebrobasilar stenosis and simple lesion morphologies (Mori types A and B). However, further research is needed for patient selection and therapy optimization.
Effect of growing season fire timing on oak regeneration
Authors: Turner Mark A. , Bones Jacob T. , Marshall Spencer G. , Harper Craig A. 
Published: January 2025

Abstract

Background
Oaks (Quercus spp.) are an important component of eastern hardwood forests, and compositional shifts away from oak are well-documented. Shelterwood harvests often are paired with prescribed fire to promote oak regeneration, as oaks may gain a competitive advantage following fire. However, we are unaware of any studies comparing the effects of multiple fires during the early-growing season (EGS) and late-growing season (LGS) following a shelterwood harvest with reserves on oak regeneration. Additionally, relatively little is known about the response of the red oak group (Erythrobalanus) versus the white oak group (Leucobalanus) regeneration to fire during different seasons.

Results
We initiated a study in east Tennessee, USA in 2010 by implementing a shelterwood with reserves in four upland oak-hickory stands. Each stand contained an EGS treatment, a LGS treatment, a shelterwood treatment with no fire (SW), and an unharvested, unburned control (CON). From 2012 to 2023, we burned the EGS and LGS treatment units six times each. By 2023, the unburned SW treatment was dominated by mesophytes with almost no oaks present in the midstory. Red oak and total understory oak regeneration was promoted by LGS relative to EGS, SW, and CON. White oak regeneration was promoted by EGS compared to CON but did not differ between fire seasonality treatments. Both burn seasons decreased the number and proportion of mesophytes, but the response of other species varied by treatment. The proportion of sassafras was increased by EGS and LGS relative to SW, but did not differ from CON. The proportion of sumac was greatest in EGS, followed by LGS, and was similarly low in CON and SW. Thus, fire increased oak abundance, but also promoted other fire-tolerant upland species.

Conclusions
Our results indicate timing of fire during the growing season can positively influence oak regeneration but does not eliminate competition. Additional management practices may be necessary as the stand develops to release oaks after burning is stopped or the fire-return interval is lengthened.
Persistent postural-perceptual dizziness: a review of current knowledge on vestibular rehabilitation
Authors: Azeez Samer Sami , Nada Ebtessam H. 
Published: January 2025

Abstract
Persistent postural-perceptual dizziness disrupts daily life, causing chronic dizziness, unsteadiness, and imbalance. Often triggered by seemingly innocuous factors like movement or visual stimuli, the underlying cause of PPPD remains elusive. This intricate interplay between physical and psychological factors presents a significant diagnostic and treatment challenge for clinicians. This review explores the recent literature focusing on complexities of PPPD management, highlighting the limitations of current approaches and advocating for a multidisciplinary perspective. PPPD diagnosis can be arduous due to the absence of a definitive test. Additionally, the lack of established treatment protocols necessitates a multifaceted approach that may include pharmacotherapy, vestibular rehabilitation therapy (VRT), and psychological interventions. Collaborative research across disciplines, including neurotology, otolaryngology, psychiatry, and psychology, is crucial for advancing our understanding of PPPD and developing more effective treatment strategies. PPPD presents a multifaceted challenge, requiring a patient-centered approach that integrates various treatment modalities. By fostering collaboration across disciplines and prioritizing patient support networks, we can illuminate a path towards improved diagnosis, management, and, ultimately, a better quality of life for those affected by PPPD.
Landscape of Global Pediatric Oncology Publications: A Cross-Sectional Analysis
Authors: García Garza María Fernanda , Gutiérrez Treviño Oscar , Hashmi Saman K. , Rodríguez-Galindo Carlos , Moreira Daniel C. 
Published: January 2025

PURPOSE
The academic field of global pediatric oncology is expanding as cancer becomes increasingly recognized as a global health priority for children and adolescents. Here, we aimed to explore the representation of authors, the geographic distribution of research, and the research approaches being used in global pediatric oncology.

METHODS

Articles published in
JCO Global Oncology
(
JCO GO
) and
Pediatric Blood and Cancer
on the topic of global pediatric oncology were analyzed. For each article, data were collected on the study design, the research location, and the authorship demographics. Descriptive frequencies were reported for all items.

RESULTS
Overall, 296 studies met the inclusion criteria to be considered relevant for global pediatric oncology. Of these, 259 (87.5%) were research articles. Of the research articles, 228 (88.0%) were observational and 117 (51.3%) were retrospective cohort analyses. Thirty-eight studies (12.8%) had a global focus or were unrelated to a geographic context, 54 (18.2%) were regional, and 204 (68.9%) were specific to a single country. Females represented 163 (55.8%) of first authors, 138 (46.6%) of senior authors, and 159 (53.7%) of corresponding authors. Furthermore, 121 (41.4%) first authors, 163 (55.1%) last authors, and 142 (48.0%) senior authors were from high-income countries (HICs). The United States (n = 81) and India (n = 40) had the most corresponding authors. Thirty-six (17.6%) articles had research conducted in low- and middle-income countries (LMICs), and the first, senior, and corresponding authors were from HICs.

CONCLUSION
Our analysis shows that researchers from LMICs are under-represented as authors of global pediatric oncology publications. Further studies are needed to evaluate the factors that contribute to inequalities in global pediatric oncology research.
Forecasting Asparaginase Need and Cost for Childhood Cancer Using ACCESS FORxECAST
Authors: Hughes Terence M. , Shrivastava Nitin , Silverman Lewis B. , Frazier A. Lindsay , Gupta Sumit , Denburg Avram 
Published: January 2025

PURPOSE
Asparaginase (ASN) is a critical component of pediatric ALL protocols. Until recently, ASN was available in three formulations: native Escherichia coli, PEGylated E. coli (PEG), and Erwinase, with native E. coli typically more accessible in low- and middle-income countries (LMICs). Short shelf lives, intermittent availability, and concern for substandard formulations in LMICs have created a need for proactive ASN demand estimates.

METHODS
We adapted FORxECAST, a pediatric cancer drug forecasting model, to focus on ASN for pediatric ALL. The model is adaptable to user data and defaults to best available public data where local data are unavailable. We forecast ASN quantity and cost in three case study countries for four scenarios using two regimens—base regimen (BR) and intensified regimen (IR)—outlining how quantity and costs vary on the basis of ASN formulation, dose, and second-line availability.

RESULTS
Native E. coli is cheaper than PEG for first-line treatment across all scenarios. Regimen intensification from BR to IR requires a substantially higher cost when PEG is used relative to native E. coli. The cost of treating ASN hypersensitivity with Erwinase for BR in Burundi, Ghana, and Turkmenistan is $19,660 in US dollars (USD), $24,800 USD, and $15,246 USD, respectively.

CONCLUSION
Treatment intensification requires a cost increase that should be accessible for most LMICs, but PEG utilization is substantially more costly, suggesting that prioritizing investment in intensifying treatment using native E. coli is the least costly approach to maximize treatment availability. Cost savings associated with native E. coli utilization may liberate funds for Erwinase procurement for patients with ASN hypersensitivity. Future analyses needed include an evaluation of costs associated with preventing abandonment due to compliance complexity with native E. coli given increased administration frequency compared with PEG.
Treatment and Outcomes of Pancreatic Cancer in Armenia: A Retrospective Study From Resource-Limited Settings
Authors: Baloyan Elen , Zohrabyan Davit , Safaryan Liana , Avagyan Armen , Harutyunyan Lilit , Bardakhchyan Vardan , Arakelyan Jemma , Sargsyan Amalya , Harutyunyan Martin , Mailyan Mariam , Tamamyan Gevorg , Bardakhchyan Samvel 
Published: January 2025

PURPOSE
Pancreatic cancer is one of the deadliest cancers in the world. In Armenia, it is 12th by incidence. The aim of this study is to evaluate treatment and outcomes of pancreatic cancer in Armenia during the past 12 years.

METHODS
This is a retrospective study with data from three oncology centers in Armenia: “Muratsan” Hospital of Yerevan State Medical University, Mikaelyan institute of surgery, and Yeolyan Hematology and Oncology Center. The information was obtained from the medical records of the patients with pancreatic cancer treated at these centers during January 1, 2010-January 1, 2022. Log-rank test and Kaplan-Meier curves were used for survival analysis. Cox regression analysis was performed for identification of main prognostic factors.

RESULTS

Of 70 patients involved in the final analysis, 45.7% was female. The median age at diagnosis was 63 years. The median follow-up time was 11 months (range, 2-146). A total of 11.4% of patients had stage I-II, 27.1% had stage III, and 60% had stage IV disease. The main independent prognostic factor for overall survival (OS) was the TNM stage, whereas grade of the tumor was not significant. The median OS was 11 months (range, 2-169 months): In stages I-III, patients who had surgery (44.4%) lived significantly longer than those who did not (20
v
11 months;
P
= .008). Main chemotherapy regimens were 5-fluorouracil, oxaliplatin, folinic acid and irinotecan (41.4%) and gemcitabine plus capecitabine (38.6%). No significant survival difference was found between these groups (13
v
11 months;
P
= .162).

CONCLUSION
Survival of patients with pancreatic cancer in Armenia is dismal, not exceeding 1 year. Hopefully, further research in the field and new treatment modalities will improve the situation.
Compreendendo o instagram no contexto do inbound marketing
Authors: Toledo Luciano Augusto , Assis Evange Elias 
Published: January 2025

o Inbound marketing é uma ferramenta do marketing focada em atrair, converter e encantar clientes e, atualmente, é uma das mais utilizadas pelas empresas que buscam manter relacionamento de longo prazo com seus consumidores. O objetivo geral deste estudo foi analisar o uso do Instagram no contexto do Inbound marketing da empresa varejista de calçados Artwalk. Os procedimentos metodológicos adotados caracterizaram o estudo como exploratório e qualitativo, utilizando-se do método do estudo de caso. Observou-se que a produção de conteúdo e o trabalho com influenciadores digitais no Instagram possibilitaram atrair maior público para a empresa. Além disso, o Instagram impulsionou o Inbound marketing, ao favorecer as vendas, melhorando a comunicação e o entendimento do comportamento do consumidor. Foram apresentadas sugestões para pesquisas futuras nesta área em expansão.
Perspektywy badań kopernikańskich a odmienne tradycje metodologiczne w 550. rocznicę urodzin Mikołaja Kopernika.
Authors: Kokowski Michał 
Published: January 2025

W artykule przedstawiamy perspektywy badań kopernikańskich jakie rysują się w 550. rocznicę urodzin Mikołaja Kopernika.
Perspektywy te zależne są od odmiennych tradycji metodologicznych, jakie przyjmują badacze. Wyróżnione zostały cztery takie tradycje: „historia jest dyskursem władzy”; „historia / badania historyczne”, „historia pamięci / badania historii pamięci”, „krytyka historyczna historii pamięci / badań historii pamięci”.
Ważną rolę w tych badaniach pełni poszukiwanie nowych źródeł historycznych, pogłębienia interpretacji dzięki zastosowaniu bogatszych hermeneutyk badawczych oraz usuwanie mitów historiograficznych.
High pulse pressure is associated with an increased risk of prediabetes in hypertensive individuals: A retrospective study based on an adult Chinese population
Authors: Wu Zhanxing , Chen Zhongqing , Zeng Wenfei , Peng Ganggang , Huang Zhenhua 
Published: January 2025

Objectives
The pulse pressure (PP) is an important factor influencing the outcomes of diabetes. However, the relationship between the PP and prediabetes has been rarely studied and how this association might be impacted by hypertension is not clear.

Methods
In this study, we retrospectively included 184,252 adults from 32 regions in China, spanning from 2010 to 2016. Cox regression and sensitivity analysis were used to examine the relationship between PP and prediabetes. For the hypertensive population, Cox proportional hazards regression and smooth curve fitting were performed to explore the non-linear relationship between PP and prediabetes. A two-stage Cox proportional hazards regression model was used to determine the inflection point of PP in relation to the risk of prediabetes.

Results
After adjusting for confounding factors, we found a positive association between PP and prediabetes (HR: 1.11, 95% CI: 1.03–1.19, P = 0.0045). However, we observed that this relationship was not significant in the normal blood pressure group (HR: 1.06, 95% CI: 0.94–1.18, P = 0.3529). We also found a non-linear relationship between PP and the risk of prediabetes in hypertensive individuals. The inflection point of PP was 31 mmHg. When PP ≥ 31 mmHg, there was a positive association with the risk of prediabetes (HR: 1.22, 95% CI: 1.04–2.08, P <0.0001). Conversely, when PP < 31 mmHg, this association was not significant (HR: 0.83, 95% CI: 0.59–1.15, P = 0.2646).

Conclusions
This study suggests a non-linear relationship between PP and the risk of prediabetes in hypertensive individuals. Maintaining PP within 31 mmHg is crucial for preventing the occurrence of prediabetes.