bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Lab Streaming Layer for Synchronized Multimodal Recording
Authors: Kothe Christian , Shirazi Seyed Yahya , Stenner Tristan , Medine David , Boulay Chadwick , Grivich Matthew I. , Mullen Tim , Delorme Arnaud , Makeig Scott 
Published: February 2024

AbstractAccurately recording the interactions of humans or other organisms with their environment or other agents requires synchronized data access via multiple instruments, often running independently using different clocks. Active, hardware-mediated solutions are often infeasible or prohibitively costly to build and run across arbitrary collections of input systems. The Lab Streaming Layer (LSL) offers a software-based approach to synchronizing data streams based on per-sample time stamps and time synchronization across a common LAN. Built from the ground up for neurophysiological applications and designed for reliability, LSL offers zero-configuration functionality and accounts for network delays and jitters, making connection recovery, offset correction, and jitter compensation possible. These features ensure precise, continuous data recording, even in the face of interruptions. The LSL ecosystem has grown to support over 150 data acquisition device classes as of Feb 2024, and establishes interoperability with and among client software written in several programming languages, including C/C++, Python, MATLAB, Java, C#, JavaScript, Rust, and Julia. The resilience and versatility of LSL have made it a major data synchronization platform for multimodal human neurobehavioral recording and it is now supported by a wide range of software packages, including major stimulus presentation tools, real-time analysis packages, and brain-computer interfaces. Outside of basic science, research, and development, LSL has been used as a resilient and transparent backend in scenarios ranging from art installations to stage performances, interactive experiences, and commercial deployments. In neurobehavioral studies and other neuroscience applications, LSL facilitates the complex task of capturing organismal dynamics and environmental changes using multiple data streams at a common timebase while capturing time details for every data frame.
Developmental emergence of quiescent-like neural progenitor cells in the zebrafish embryonic brain
Authors: Liu Yuanyuan , Lembke Carla-Sophie , Paridaen Judith TML 
Published: February 2024

AbstractThe mature brain is made up of differentiated neurons and glial cells that are produced by embryonic neural stem and progenitor cells (collectively called neural stem cells (NSCs)) during brain development. In contrast, adult NSCs generate only a limited number of neuronal and glial cell types. Moreover, in contrast to embryonic NSCs, adult NSCs spend most of their time in a non-dividing resting phase called quiescence. In the adult brain, the quiescent NSCs are activated at a low frequency to divide and produce new cells to replace lost or damaged mature cells.Previous studies have demonstrated that about halfway through mammalian brain development, a subset of the embryonic NSCs population slows down their division rate and slowly transition into adult quiescent NSCs (qNSCs). However, the molecular mechanisms that underlie the emergence of the pre-adult SCs remain largely unknown.Here, we explored single-cell transcriptomes from several embryonic stages of zebrafish development in order to determine at what developmental stage transcriptional signatures typical of adult quiescent NSCs first emerge. We identified a subpopulation of embryonic NSCs with a distinct transcriptional profile from other embryonic NSCs. This population shares transcriptional similarities with adult qNSCs including genes known to maintain quiescence. We propose that this population constitute slower cycling embryonic NSCs that may transition into the adult qNSCs of the adult zebrafish brain.
Individual differences in the boldness of female zebrafish are associated with alterations in serotonin function
Authors: Beigloo Fatemeh , Davidson Cameron J. , Gjonaj Joseph , Perrine Shane A. , Kenney Justin W. 
Published: February 2024

AbstractOne of the most prevalent axes of behavioral variation in both humans and animals is risk taking, where individuals that are more willing to take risk are characterized as bold while those that are more reserved as shy. Brain monoamines (i.e., serotonin, dopamine, and norepinephrine) have been found to play a role in a variety of behaviors related to risk taking. Genetic variation related to monoamine function have also been linked to personality in both humans and animals. Using zebrafish, we investigated the relationship between monoamine function and boldness behavior during exploration of a novel tank. We found a sex-specific correlation between serotonin metabolism (5-HIAA:5-HT ratio) and boldness that was limited to female animals; there were no relationships between boldness and dopamine or norepinephrine. To probe differences in serotonergic function, we administered a serotonin reuptake inhibitor, escitalopram, to bold and shy fish, and assessed their exploratory behavior. We found that escitalopram had opposing effects on thigmotaxis in female animals with bold fish spending more time near the center of the tank and shy fish spent more time near the periphery. Taken together, our findings suggest that variation in serotonergic function makes sex-specific contributions to individual differences in risk taking behavior.
Dissecting the contribution of vagal subcircuits in sepsis-induced brain dysfunctions
Authors: Bourhy Lena , Moigneu Carine , Dupin Alice , Hecquet Estéban , Levy Jarod , Sharshar Tarek , Lledo Pierre-Marie , Lepousez Gabriel 
Published: February 2024

AbstractSepsis, a life-threatening syndrome caused by a dysregulated host response to infection, induces a range of acute effects on the brain, including sickness behaviour and sepsis-associated encephalopathy. In addition, sepsis can lead to durable changes in neuronal circuits, resulting in long-term impairments such as post-traumatic stress disorder (PTSD). These brain dysfunctions are not directly caused by brain infection but result from peripheral inflammatory signals relayed to the brain via neural and humoral pathways. The vagal complex in the brainstem, composed of the nucleus of the solitary tract (NTS) and the area postrema, plays a crucial role in sensing and relaying these signals. Notably, the activation of the vagal complex triggers neurovegetative, neuroendocrine, and behavioural responses to infection. Chronic electrical vagus nerve stimulation has been used clinically to treat various brain disorders and is being investigated for its potential to alleviate inflammation and immune diseases through the anti-inflammatory reflex. However, a deeper understanding of the involvement of the vagus nerve and downstream brain circuits in sepsis-induced brain activation and dysfunction is needed to optimize therapeutic strategies.To investigate the role of the vagal complex in sepsis-induced brain dysfunction, various techniques were employed to manipulate vagus nerve activity and downstream circuits in a rodent model of sepsis by caecal ligation and puncture. Subdiaphragmatic vagotomy and pharmacogenetic manipulation of NTS and nodose (i.e. vagus sensory neurons) were implemented, revealing that vagotomy effectively reduced acute brain activation, inflammatory responses, and sickness behaviour triggered by sepsis. Additionally, transient activation of NTS neurons had a significant impact on inflammatory responses, sickness behaviour, and long-term PTSD-like consequences. This study underscores the complex interplay among the vagus nerve, brain circuits, and systemic inflammation during sepsis, emphasizing the critical importance of understanding these interactions in the development of targeted therapeutic interventions.
TheDrosophilahistone methyl-transferase SET1 coordinates multiple signaling pathways in regulating male germline stem cell maintenance and differentiation
Authors: Vidaurre Velinda , Song Annabelle , Li Taibo , Ku Wai Lim , Zhao Keji , Qian Jiang , Chen Xin 
Published: February 2024

AbstractMany cell types come from tissue-specific adult stem cells that maintain the balance between proliferation and differentiation. Here, we study how the H3K4me3 methyltransferase, Set1, regulates early-stage male germ cell proliferation and differentiation inDrosophila. Early-stage germline-specific knockdown ofset1results in a temporally progressed defects, arising as germ cell loss and developing to overpopulated early-stage germ cells. These germline defects also impact the niche architecture and cyst stem cell lineage in a non-cell-autonomous manner. Additionally, wild-type Set1, but not the catalytically inactive Set1, could rescue theset1knockdown phenotypes, highlighting the functional importance of the methyl-transferase activity of the Set1 enzyme. Further, RNA-seq experiments reveal key signaling pathway components, such as the JAK-STAT pathway genestat92Eand the BMP pathway genemad, that are upregulated uponset1knockdown. Genetic interaction assays support the functional relationships betweenset1and JAK-STAT or BMP pathways, as mutations of both thestat92Eandmadgenes suppress theset1knockdown phenotypes. These findings enhance our understanding of the balance between proliferation and differentiation in an adult stem cell lineage. The germ cell loss followed by over-proliferation phenotypes when inhibiting a histone methyl-transferase raise concerns about using their inhibitors in cancer therapy.
Shifting ethical priorities and the architectural profession: a systematic review of recent research and its alignment with contemporary professional codes of conduct
Authors: Gillon Charles , Ostwald Michael J. , Easthope Hazel 
Published: February 2024

PurposeThe architectural profession faces an increasingly complex ethical landscape. In recent decades, the ethical foundations for architecture – formally defined in professional codes of conduct and reflected in regulatory frameworks – have expanded to incorporate imperatives derived from environmental and social responsibilities. The present research examines how these expanding ethical expectations are reflected in, and supported by, recent research about architectural ethics.Design/methodology/approachAnalysis is based on a systematic review of recent research (2002–2023) focussing on ethical values and associated behaviours in the architectural profession. The review identifies 37 research articles (from a starting set of 2,483 articles), which are analysed empirically and then qualitatively to draw out views around three types of ethical behaviour. The paper then discusses how these findings align thematically with the evolving ethical needs of architectural practitioners (as defined in the professional codes of ethics and conduct of the RIBA in the UK, AIA in Australia and the AIA in the USA).FindingsWhile business ethics remains the focus of past research, there has been a rise in research about ethics and social and environmental factors. The content of professional codes reflects this shift, setting the conditions for architects to aspire to increased expectations of environmental and social responsibility.Originality/valueThis article undertakes the first systematic review of recent research about architectural ethics and its alignment with the content of contemporary professional codes. Organised thematically, recent research about ethical values and associated behaviours can offer guidance for the evolving ethical needs of architects.
Toward unique electrical ladder network model synthesis of a transformer winding high-frequency modeling using K-means and metaheuristic-based method
Authors: Chanane Abdallah , Houassine Hamza 
Published: February 2024

Purpose
Although, numerous optimization algorithms have been devoted to construct an electrical ladder network model (ELNM), they suffer from some frail points such as insufficient accuracy as well as the majority of them are unconstrained, which result in optimal solutions that violate certain security operational constraints. For this purpose, this paper aims to propose a flexible-constraint coyote optimization algorithm; the novelty lies in these points: penalty function is introduced in the objective function to discard any unfeasible solution, an advanced constraint handling technique and empirical relationship between the physical estimated parameters and their natural frequencies.

Design/methodology/approach
Frequency response analysis (FRA) is very significant for transformer winding diagnosis. Interpreting results of a transformer winding FRA is quite challenging. This paper proposes a new methodology to synthesize a nearly unique ELNM physically and electrically coupled for power transformer winding, basing on K-means and metaheuristic algorithm. To this end, the K-means method is used to cluster the setting of control variables, including the self-mutual inductances/capacitances, and the resistances parameters. Afterward, metaheuristic algorithm is applied to determine the cluster centers with high precision and efficiency.

Findings
FRA is performed on a power transformer winding model. Basing on the proposed methodology, the prior knowledge in selecting the initial guess and search space is avoided and the global solution is ensured. The performance of the abovementioned methodology is compared using evaluation expressions to verify its feasibility and accuracy.

Originality/value
The proposed method could be generalized for diagnosis of faults in power transformer winding.
The quest for an optimal capital structure: an empirical analysis of European firms using GMM regression analysis
Authors: Demiraj Rezart , Labadze Lasha , Dsouza Suzan , Demiraj Enida , Grigolia Maya 
Published: February 2024

Purpose This paper explores the connection between capital structure and financial performance within European listed firms. The primary objective is to demonstrate an inverse U-shaped relationship between these two variables and pinpoint an optimal debt-equity mix.Design/methodology/approach In this study, we adopt a dynamic modeling approach to investigate the relationship between a firm’s capital structure and financial performance. Drawing on well-established theories and prior empirical studies, our model examines 3,121 dividend-paying firms from 41 European countries over 14 years, from 2008 to 2021. To enhance the reliability of our findings, we employ two distinct estimation techniques: the fixed effect model (FE) and the system generalized method of moments (System-GMM).Findings This study reveals an inverse U-shaped relationship between the firm’s financial performance, measured by the return on equity (ROE) and its capital structure (total liability to total assets ratio). Furthermore, an optimal capital structure of about 29% is determined for all firms in the sample, and about 21%, 28% and 41% industry-specific capital structure for manufacturing, real estate and wholesale trade, respectively.Originality/value This paper contributes to existing knowledge by empirically determining an optimal capital structure for listed firms across various industries in Europe, which very few studies have attempted to do in the past. An optimal capital structure is an invaluable benchmark for managers and other stakeholders, informing their decision-making.
Does the market value energy efficiency within EPC-labels? An analysis of the residential real estate market in Flanders
Authors: Gerassimenko Alesia , De Moor Lieven , Defau Laurens 
Published: February 2024

Purpose
The current literature has not investigated the perceived value of energy efficiency by households, regardless of financial benefits. Furthermore, there is a severe lack of research that investigates the effectiveness of the current format of EPC-labels. Therefore, the purpose of this paper is twofold: to study how households value energy efficiency in the housing market, regardless of price effects.

Design/methodology/approach
This study uses multiple hedonic regression models to analyse 706,778 Flemish properties for sale or rent between 2019 and 2023. The data is provided by Immoweb – the largest online real estate platform in Belgium. Given that the selling market is driven by different mechanisms than the rental market, the data set was divided in sold (522,164 listings) and rented properties (184,614 listings).

Findings
The ambiguous results of the A-label in the selling market indicate that the “class evaluation effect” found in related markets which use labels (e.g. household appliances) is also present in the housing market. However, the results of the other (lower) labels clearly show that owners do value energy improvements within labels, and this effect becomes stronger as the EPC-label becomes better. The rental market shows the opposite results. Energy improvements are only valued if they translate into a financial benefit. Taking these findings into account, the second part of this research shows that rescaling the EPC-label creates an incentive for improvements within labels.

Originality/value
This paper provides novel insights by studying the perceived value of energy efficiency in the absence of financial benefits and critically studying the effectiveness of the EPC-labels in their current shape. By investigating both the sales and rental market, the authors are able to make a comparison which creates valuable insights for academia, governments and real estate professionals.
Drama and organisational culture: an exploration of Aristotle’s “Poetics” as a conceptual dramatic framework in the design of organisational culture
Authors: D’souza Anil 
Published: February 2024

Purpose
The paper draws extensively from Aristotle’s Poetics, a classical work on the aesthetics of drama. Drawing from symbolic and thematic elements from folklore and mythology, this paper aims to illustrate how the Poetics can be referenced as an allegorical device in the design of culture-building strategies and interventions.

Design/methodology/approach
This exploratory paper examines Aristotle’s “Poetics” and the range of creative expression this literature provides as a conceptual design framework for the development of a culture map in creating a distinctive organisational mythology. The Poetics articulates an Aristotelian perspective on theatre which infuses itself as a new language in offering structural and archetypical plot devices in the development of an organisational narrative.

Findings
Findings from this explorative study can provide a creative roadmap to culture practitioners and leaders, to be used as a determining reference point in developing culture maps and change management interventions.

Practical implications
Poetics has its detractors, notably Bertolt Brecht and Augusto Boal. Boal examines how Poetics promotes a narrative that suppresses free thinking and encourages a cult of feudal personality, therefore encouraging industrial and cultural oppression, which he rebelled against through the development of his “Theatre of the Oppressed”. This new kind of theatre discarded the Aristotelian model of thinking. Ideas proposed in the Poetics may also lend verisimilitude to the propagation of obsessive consumerism through the definitive symbolism it offers in the development of institutionalised personality cults.

Originality/value
The Poetics as a creatively driven reflexive study provides a forward movement in the study of culture design templates. Its definitive allegorical devices and metaphors act as action principles through which an enterprise culture and its value system can be examined and developed.
Why should we trust our public leaders in Africa? A comparative analysis between 2019 and 2021
Authors: Dzordzormenyoh Michael K. 
Published: February 2024

PurposeThis study investigates the factors that influence citizens trust in public leaders [i.e. presidents, members of parliament (MPs) and local government leaders (LGs)] in 34 countries in Africa between 2019 and 2021.Design/methodology/approachIndividual-level data with a sample size of 48,084 was obtained from the Afro-Barometer round 8 survey only and analyzed using multivariate binary logistic regression.FindingsSeveral important and intriguing observations were made from this analysis: (1) the performance of public leaders influences citizens trust in their leaders; (2) the perceived corruption of public leaders and civil servants and the level of corruption influence citizens trust in public leaders; (3) perceived neighborhood problems (i.e. fear of violence, fear of terrorism and service delivery) influence citizens trust in their public leaders and (4) the socio-demographic characteristics of citizens (i.e. age, religion, education, location, employment and political party affiliation) influence citizens trust in their public leaders.Originality/valueThis study is exceptional in two ways: (1) it examines and compares citizens trust in public leaders across different levels, i.e. presidents, MPs and LGs in Africa and (2) it examines and compares the factors influencing citizens trust in public leaders in Africa comparatively.
Testing the effects of moral intensity news frames on consumer boycott intention
Authors: Bravo Olivia Stacie-Ann Cleopatra , Chapa Sindy 
Published: February 2024

Purpose
This exploratory research examined how emphasizing a brand’s unethical behaviour through high moral intensity news framing influences consumer boycott intention.

Design/methodology/approach
The hypotheses were tested and validated using two experimental studies that expose customers of real retail and personal care product brands to news articles that have high and low moral intensity news frames.

Findings
The results showed high moral intensity news framing’s positive effect on consumer boycott intention. The frame’s influence is moderated by moral awareness and partially mediated by perceived moral intensity and moral judgement. The findings suggest that consumers’ perception of the frame and their attitude towards the brand will have a substantial role in boycott intention.

Practical implications
These research outcomes aid in the understanding of news framing effects on boycott intention, providing both insights for consumer activists and managerial implications for stewards of brands.

Originality/value
While previous research have examined the impact of news frames on the typical audience, there has been relatively little focus on news framing’s impact on consumers and their decision to boycott brands. This study addresses this gap by applying the work on emphasis framing to a consumer decision-making context. It also introduces moral intensity framing to the news frame classification. In addition, this study expands current conceptualizations of individual ethical decision-making to help explain consumer boycott intent.