bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing the incorporation of battery degradation in vehicle-to-grid optimization models
Authors: Preis Valentin , Biedenbach Florian 
Published: October 2023

AbstractBidirectional charging allows energy from the electric vehicles (EV) to be fed back into the grid, offering the possibility of price-optimized charging. However, such strategies cause higher charging cycles, which affect the cyclic aging of the battery and reduce its service life, resulting in additional costs for the user. Various approaches are used to account for battery degradation in optimizations models of bidirectional charging use-cases. In this paper, a systematic literature review is carried out to identify existing battery degradation models and to determine the most suitable one. In the models under review, degradation is integrated into the optimization’s objective function. The review shows that there are mainly two strategies suitable for vehicle-to-grid (V2G) optimization problems: A weighted Ah-throughput model (wAh-model) with a constant degradation cost factor and a performance based model (pb-model) linking the degradation to measurable parameters such as capacity loss. Both models were implemented and analyzed. The results show that the wAh-model is the better optimization option, as in the pb-model the current state of health of the battery has an excessively large impact on the calculated degradation cost. It leads to excess costs due to a higher aging rate at the beginning of life which proves to be not ideal in the optimization. The sensitivity analysis reveals that altering the initial State of Health (SoH) from 95 % in the base scenario to 100 % leads to an increase in average degradation costs by factor 9.71 in the pb-model. From the evaluated base scenario the average degradation costs for the pb-model are 0.45 cent/kWh and for the wAh-model 0.23 cent/kWh.
RETRACTED ARTICLE: Analyzing the impacts of node density and speed on routing protocol performance in firefighting applications
Authors: Ullah Inam , Hussain Tariq , Khan Aamir , Ali Iqtidar , Ali Farhad , Choi Chang 
Published: October 2023

Abstract
Background
Mobile ad hoc networks have piqued researchers’ interest in various applications, including forest fire detection. Because of the massive losses caused by this disaster, forest fires necessitate regular monitoring, good communication, and technology. As a result, disaster response and rescue applications are mobile ad hoc network’s primary applications. However, quality of service becomes a significant and difficult issue, and the capabilities of the basic routing protocol limit mobile ad hoc network’s ability to deliver reasonable quality of service.

Results
The proposed research is for disaster-related scenarios, with nodes representing firefighters and vehicles (ambulances). Mobile nodes moving at 10 m/s are thought to be firefighters, while nodes moving at 20 m/s are thought to be vehicles (ambulances) delivering emergency healthcare. The NS-2 simulator is used in this research for the performance assessment of the two routing protocols, such as Optimized Link State Routing (OLSR) and Temporally Order Routing Algorithm (TORA), in terms of average latency, average throughput, and average packet drop. The simulation was run with varying node velocities and network densities to examine the impact of scalability on the two mobile ad hoc network routing protocols.

Conclusions
This work presents two main protocols: TORA (for reactive networks) and OLSR (for proactive networks). The proposed methods had no impact on the end-to-end bandwidth delay or the packet delivery delay. The performance is evaluated in terms of varying network density and node speed (firefighter speed), i.e., varying network density and mobility speed. The simulation revealed that in a highly mobile network with varying network densities, OLSR outperforms TORA in terms of overall performance. TORA’s speed may have been enhanced by adding more nodes to the 20 nodes that used a significant amount of transmission control protocol traffic.
Abolition Infrastructures
Authors: Ansfield Bench , Herzing Rachel , Spade Dean 
Published: October 2023

Abstract
Over the past two decades, transformative justice has gained momentum as an organized effort to answer contemporary abolitionism’s thorniest question: How can a society handle the problem of harm without resorting to punishment? The movement has sought to develop responses to harm and violence that reject retribution and instead emphasize accountability, repair, care, and attention to the systemic roots of violence. In large part because the movement took form in explicit rejection of the state’s administration of justice, the work of transformative justice has most frequently been done on an unpaid basis of mutual aid. Here’s a movement that has germinated in collective homes, borrowed office spaces, online forums, activist convenings, parks—in other words, in the abolitionist commons. As transformative justice has gained currency over the course of the pandemic, its ideas have been taken up in new realms, including the university, the nonprofit, the prison, and the courts. The current moment is ripe for taking stock of where the movement is right now, and where it is going. What does it look like to build toward abolition infrastructures or infrastructures of collective care? How might an abolitionist theory of the state guide this work?
Escritas performativas: três estudos de caso brasileiros
Authors: Caputo Irma 
Published: October 2023

O presente artigo investiga o conceito de escritas performativas a partir de três casos literários brasileiros que apresentam graus diferenciados de performatividade no tipo de hibridização de práticas de linguagens propostas e no tipo de coação aplicada às regras prescritivas e normativas do código verbal. A partir dos casos selecionados O peso do pássaro morto (2017) de Aline Bei, Ó (2008) de Nuno Ramos, Corpografia (1992) de Josely Vianna Baptista e Francisco Farias serão investigadas as operações de linguagem que permitem definir essas escritas performativas, analisando tanto a forma como a linguagem verbal tenta sair da sua semioticidade intrínseca quanto às práticas estéticas incorporadas advindas de outras artes. Cada exemplo tratado estabelece uma relação mais íntima com áreas diversas, tais como teatro, artes plásticas e fotografia. Serão enfim avaliados quais os resultados comuns alcançados na recepção, independentemente do tipo de procedimentos estéticos utilizados e de que maneira novas formas sensíveis da literatura podem acarretar novos cortes epistemológicos.
Energy-scaling of a diode-pumped Alexandrite laser and prototype development for a compact general-purpose Doppler lidar
Authors: Munk Alexander , Scheuer Sarah , Strotkamp Michael , Jungbluth Bernd , Froh Jan , Mense Thorben , Mauer Alsu , Höffner Josef 
Published: October 2023

We present design and performance data of an energy-scaled diode-pumped Alexandrite laser in single longitudinal mode operation developed as a beam source in a mobile general-purpose Doppler lidar. A maximum pulse energy in Q-switched operation of 4.6 mJ and a maximum average power of 2.7 W were achieved for a repetition rate range from 500 to 750 Hz with excellent beam quality of M2=1.1. Two rugged and compact demonstrator lasers were built and integrated into mobile lidar systems, where a bandwidth of approximately 3 MHz is measured. Measurements of atmospheric winds and temperatures were conducted during several field campaigns from summer 2022 to spring 2023.
Wnt10b protects cardiomyocytes against doxorubicin-induced cell death via MAPK modulation
Authors: Chen Lei , Byer Stefano H. , Holder Rachel , Wu Lingyuan , Burkey Kyley , Shah Zubair 
Published: October 2023

Background
Doxorubicin, an anthracycline chemotherapeutic known to incur heart damage, decreases heart function in up to 11% of patients. Recent investigations have implicated the Wnt signaling cascade as a key modulator of cardiac tissue repair after myocardial infarction. Wnt upregulation in murine models resulted in stimulation of angiogenesis and suppression of fibrosis after ischemic insult. However, the molecular mechanisms of Wnt in mitigating doxorubicin-induced cardiac insult require further investigation. Identifying cardioprotective mechanisms of Wnt is imperative to reducing debilitating cardiovascular adverse events in oncologic patients undergoing treatment.

Methods
Exposing human cardiomyocyte AC16 cells to varying concentrations of Wnt10b and DOX, we observed key metrics of cell viability. To assess the viability and apoptotic rates, we utilized MTT and TUNEL assays. We quantified cell and mitochondrial membrane stability via LDH release and JC-1 staining. To investigate how Wnt10b mitigates doxorubicin-induced apoptosis, we introduced pharmacologic inhibitors of key enzymes involved in apoptosis: FR180204 and SB203580, ERK1/2 and p38 inhibitors. Further, we quantified apoptotic executor enzymes, caspase 3/7, via immunofluorescence.

Results
AC16 cells exposed solely to doxorubicin were shrunken with distorted morphology. Cardioprotective effects of Wnt10b were demonstrated via a reduction in apoptosis, from 70.1% to 50.1%. LDH release was also reduced between doxorubicin and combination groups from 2.27-fold to 1.56-fold relative to the healthy AC16 control group. Mitochondrial membrane stability was increased from 0.67-fold in the doxorubicin group to 5.73 in co-treated groups relative to control. Apoptotic protein expression was stifled by Wnt10b, with caspase3/7 expression reduced from 2.4- to 1.3-fold, and both a 20% decrease in p38 and 40% increase in ERK1/2 activity.

Conclusion
Our data with the AC16 cell model demonstrates that Wnt10b provides defense mechanisms against doxorubicin-induced cardiotoxicity and apoptosis. Further, we explain a mechanism of this beneficial effect involving the mitochondria through simultaneous suppression of pro-apoptotic p38 and anti-apoptotic ERK1/2 activities.
DNMT3A-mediated epigenetic silencing of SOX17 contributes to endothelial cell migration and fibroblast activation in wound healing
Authors: Yu Xiaoping , Ma Xiaoting , Zhou Junli 
Published: October 2023

Background
Wound healing, especially impaired chronic wound healing, poses a tremendous challenge for modern medicine. Understanding the molecular mechanisms underlying wound healing is essential to the development of novel therapeutic strategies.

Methods
A wound-healing mouse model was established to analyze histopathological alterations during wound healing, and the expression of SRY-box transcription factor 17 (SOX17), DNA methyltransferase 3 alpha (DNMT3A), and a specific fibroblast marker S100 calcium-binding protein A4 (S100A4) in wound skin tissues was tested by immunofluorescence (IF) assay. Cell proliferation and migration were evaluated using 5-ethynyl-2′-deoxyuridine (EdU) and Transwell migration assays. RT-qPCR and western blotting were used to measure RNA and protein expression. Enzyme-linked immunosorbent assay (ELISA) was performed to detect the secretion of transforming growth factor-beta (TGF-β). Chromatin immunoprecipitation followed by qPCR (ChIP-qPCR) and DNA pull-down assays were performed to confirm the interaction between DNMT3A and the CpG island of the SOX17 promoter. Promoter methylation was examined by pyrosequencing.

Results
SOX17 and DNMT3A expression were regularly regulated during the different phases of wound healing. SOX17 knockdown promoted HUVEC migration and the production and release of TGF-β. Through establishing an endothelial cells-fibroblasts co-culture model, we found that SOX17 knockdown in HUVECs activated HFF-1 fibroblasts, which expressed α-smooth muscle actin (α-SMA) and type I collagen (COL1). DNMT3A overexpression reduces SOX17 mRNA levels. ChIP-qPCR and DNA pull-down assays verified the interaction between DNMT3A and CpG island in the SOX17 promoter region. Pyrosequencing confirmed that DNMT3A overexpression increased the methylation level of the SOX17 promoter.

Conclusion
DNMT3A-mediated downregulation of SOX17 facilitates wound healing by promoting endothelial cell migration and fibroblast activation.
Willingness to use long-acting injectable PrEP among HIV-negative/unknown men who have sex with men in mainland China: A cross-sectional online survey
Authors: Fu Jiaqi , Dai Zhenwei , Wang Hao , Si Mingyu , Chen Xu , Wu Yijin , Xiao Weijun , Huang Yiman , Yu Fei , Mi Guodong , Su Xiaoyou 
Published: October 2023

Background
Men who have sex with men (MSM) are at high risk of HIV acquisition. Long-acting injectable-pre-exposure prophylaxis (LAI-PrEP), requiring less frequent dosing, is being studied as an alternative method to daily oral HIV PrEP. With the addition of this potential new prevention method, it expands the scope for a wider user choice and is expected to increase the acceptability and uptake of HIV prevention measures. The aim of our study was to explore the willingness to use LAI-PrEP and associated influential factors.

Methods
Participants were recruited from December 2020 to March 2021 through banner advertisements on web- and mobile app-based platforms on Blued, a large gay Chinese social media platform. MSM in our cross-sectional study was HIV-negative and currently lived in mainland China. Participants were asked about their willingness to use LAI-PrEP and reasons why they might be or not be willing to use LAI-PrEP. Multivariable logistic regression was used to analyze the factors associated with the willingness to use LAI-PrEP.

Results
In total, 969 participants met the inclusion criteria and finished the survey. Nearly twenty percent (19.5%) of participants had never tested for HIV; 66.8% of MSM had multiple male partners; and 51.6% of MSM engaged in condomless sex with their partner. About three-fifths (66.3%) of MSM were aware of PrEP, and only 3.9% of MSM had used PrEP before. The willingness to use LAI-PrEP among MSM was 74.0% (95% CI: 71.4%-76.6%). MSM with higher education levels were less likely to show a willingness to use LAI-PrEP (AOR = 0.56, 95%CI: 0.38–0.84). Participants who had a history of HIV test (AOR = 1.68, 95%CI: 1.11–2.55), were willing to use daily oral PrEP (AOR = 10.64, 95%CI:7.43–15.21), had multiple male sexual partners (AOR = 1.33, 95%CI:0.93–1.90), who used rush popper(AOR = 1.49, 95%CI:1.05–2.13), and who were aware of PEP (AOR = 1.66, 95%CI: 1.02–2.70) were more likely to show willingness to use LAI-PrEP.

Conclusions
In our study, MSM had quite high awareness but low uptake of PrEP. As LAI-PrEP is expected to be approved for use in China in the future, our study of MSM highlights the need for key population-focused education programs about PrEP and healthy sexual behavior. This study also provides some evidence for LAI-PrEP use among the Chinese MSM population in the future.
A Percutaneous Endoscopic Colostomy Tube to the Rescue
Authors: Numan Laith , Brotherton Tim , Baliss Michelle , Ghosh Soumojit , Lamm Vladimir , Klos Coen , Sayuk Gregory , Presti Michael , Elwing Jill 
Published: October 2023

ABSTRACT
Percutaneous endoscopic colostomy (PEC) tube placement is a minimally invasive procedure used to treat recurrent colonic pseudo-obstruction, sigmoid volvulus, chronic intractable constipation, and neurogenic bowel. PEC is a viable treatment alternative for patients who have failed conservative therapies and are deemed high risk for surgical management. We present a case of acute colonic pseudo-obstruction after Clostridioides difficile infection that was unresponsive to medical treatment or endoscopic decompression. A PEC tube was placed into the transverse colon with successful resolution of the colonic distension.
Association between serum 25-hydroxyvitamin D and prostate-specific antigen: a retrospective study in men without prostate pathology
Authors: Laguna Javier , Wijngaard Robin , Hidalgo Susana , González-Escribano Cristina , Ortiz Victoria , Bedini José Luis , Filella Xavier 
Published: October 2023

Abstract

Objectives
Recently, vitamin D status has been associated with prostate cancer risk. However, some studies argue that there is no association of vitamin D with prostate cancer risk and serum prostate-specific antigen (PSA) concentrations. No clear conclusions can be drawn from the studies found in the literature. Our aim was to assess the relationship between PSA and 25-hydroxyvitamin D [25(OH)D].

Methods
We selected 415 individuals without prostate pathologies and subgroups were generated according to age and 25(OH)D. Statistical analyses were performed using Shapiro–Wilk test, Student’s t and ANOVA tests, and Pearson’s correlation. Besides, the minimum sample size needed to obtain statistically significant results between groups according to 25(OH)D concentration was calculated and a Student’s t-test for paired samples was performed to study individuals with two PSA measurements over time, where 25(OH)D concentration increased or decreased more than 25 %.

Results
We observed a slight correlation between age and PSA concentration (r=0.379, p<0.001). However, we found no significant differences when we compared PSA concentrations between groups according to 25(OH)D concentrations (p=0.891): 1.25 ± 1.32 μg/L (group with 25(OH)D<50 nmol/L) and 1.17 ± 0.90 (group with 25(OH)D≥50 nmol/L). Pearson’s correlation coefficient was close to 0. The minimum samples size to obtain statistically significant results was 815,346 men, and we observed no differences in PSA concentrations in individuals with two measurements.

Conclusions
Our findings show no association in men without prostate pathologies, based on 25(OH)D levels.
Association of low pregnancy associated plasma protein-A with increased umbilical artery pulsatility index in cases of fetal weight between the 3rd and 10th percentiles: a retrospective cohort study
Authors: Dias da Silva Carolina , Sarmento Gonçalves Inês , Ramalho Carla 
Published: October 2023

Abstract

Objectives
This study aims to evaluate if low levels of serum maternal pregnancy associated plasma protein-A (PAPP-A) during the first trimester are related to increased umbilical artery pulsatility index (UA PI) later in pregnancy, in cases of estimated fetal weight between the 3rd and 10th percentiles, in order to establish PAPP-A as a predictor of this particular cases of fetal growth restriction (FGR).

Methods
An observational, retrospective cohort study, conducted at a tertiary University Hospital located in Oporto, Portugal. Pregnant women who did the first trimester combined screening, between May 2013 and June 2020 and gave birth in the same hospital, with an estimated fetal weight (EFW) between the 3rd and 10th percentiles were included. The primary outcome is the difference in increased UA PI prevalence between two groups: PAPP-A<0.45 MoM and PAPP-A≥0.45 MoM. As secondary outcomes were evaluated differences in neonatal weight, gestational age at delivery, cesarean delivery, neonatal intensive care unit hospitalization, 5-min Apgar score below 7 and live birth rate between the same two groups.

Results
We included 664 pregnancies: 110 cases of PAPP-A<0.45 MoM and 554 cases with PAPP-A≥0.45 MoM. Increased UA PI prevalence, which was the primary outcome of this study, was significantly different between the two groups (p=0.005), as the PAPP-A<0.45 MoM group presents a higher prevalence (12.7 %) when compared to the PAPP-A≥0.45 MoM group (5.4 %). The secondary outcome cesarean delivery rate was significantly different between the groups (p=0.014), as the PAPP-A<0.45 MoM group presents a higher prevalence (42.7 %) than the PAPP-A≥0.45 MoM group (30.1 %). No other secondary outcomes showed differences between the two groups.

Conclusions
There is an association of low serum maternal PAPP-A (<0.45 MoM) during the first trimester and increased UA PI (>95th percentile) later in pregnancy, in cases of EFW between the 3rd and 10th percentiles. However, this association is not strong enough alone for low PAPP-A to be a reliable predictor of increased UA PI in this population.
Study and prediction analysis on road performance of basalt fiber permeable concrete
Authors: Wang Wenhua , Zhu Jinzhong , Cheng Xiaojun , Jiang Da , Shi Guoqin , Chen Xinghan 
Published: October 2023

Abstract
To analyze the influence of basalt fiber on the performance of permeable concrete for road applications, this study focuses on two key performance indicators: compressive strength and permeability coefficient of basalt fiber permeable concrete. Based on orthogonal experimental data, regression prediction equations were established using SPSS software to assess the effects of different fiber parameters on the compressive strength and permeability coefficient. The predicted results were then compared with experimental data. The findings indicate that the average relative error of the predicted values for both performance indicators is within a manageable range of 5%, demonstrating a high prediction accuracy. Using these regression equations, we can examine the variations in the road performance of basalt fiber permeable concrete under different fiber parameter conditions, thereby overcoming the limitations of conducting numerous parameter analysis experiments.
Rahmenwerk für die vier Phasen der digitalisierten Wertstrommethode
Authors: Erlach Klaus , Böhm Markus , Böttcher Lena , Gessert Stephan , Kegler Sarah , Teriete Tim , Ungern-Sternberg Roman 
Published: October 2023

Abstract
In seinem Ursprung ist der Wertstrom eine zutiefst analoge Methode zur zielorientierten Produktionsoptimierung. Bei der Digitalisierung der Wertstrommethode sind bisher zahlreiche Insellösungen entwickelt worden, die sich auf spezifische Phasen und Anwendungsfälle beziehen. Erforderlich ist jedoch ein Gesamtkonzept von Datenmodell und Methodik, um eine durchgängige und fehlerfreie Digitalisierung zu ermöglichen. Als Grundlage zukünftiger Forschungsaktivitäten beschreibt dieser Artikel ein Rahmenwerk für die gesamte digitalisierte Wertstrommethode, das auf den bewährten PDCA-Zyklus zurückgreift und die vier Phasen der Wertstrommethode darin einordnet: Von Wertstromkartierung über Wertstromanalyse und Wertstromdesign bis hin zum Wertstrommanagement.
Menschzentrierte Digitalisierung im Sondermaschinenbau
Authors: Schmidt Daniela , Kuhn Dominik , Becker Daniel , Müller Rainer , Bierwirth Kathrin , Hielscher Volker 
Published: October 2023

Abstract
Der zunehmende Trend zur Digitalisierung im produzierenden Gewerbe zwingt kleine und mittlere Unternehmen (KMU) dazu, einen komplexen Transformationsprozess zu durchlaufen und innovative Lösungen zu implementieren, um wettbewerbsfähig zu bleiben. Am Beispiel eines stahlverarbeitenden KMUs wird in dieser Studie der Digitalisierungsprozess von Teilen des Fertigungsworkflows unter Anwendung eines meProjektmanagementansatzes zur Verbesserung der Usability und Akzeptanz dargestellt. Zum Ende der Projektlaufzeit soll ein Verbreitungs- und Transferkonzept für branchenähnlichen KMU zur Verfügung stehen.
Einsatz von grünem Wasserstoff im Verkehrssektor
Authors: Mais Franziska , Gümbel Till , Gramberg Till , Jelschow Vladimir , Gross Erwin , Sauer Alexander 
Published: October 2023

Abstract
Das Potenzial von grünem Wasserstoff (folglich als H2) im Verkehrssek-tor wurde für die Region Schwarzwald untersucht und eine Roadmap mit Maßnahmen für einen erfolgreichen Markthochlauf entwickelt. Durch eine Metastudienanalyse wurde der Bedarf für H2 ermittelt. Über eine qualitative und quantitative Datenerhebung wurden Perspektiven von Expert:innen für die Aufstellung von Szenarioannahmen für den H2-Bedarf generiert. Basierend auf den Ergebnissen wurde eine Roadmap erstellt, die die notwendigen Schritte in den Bereichen Infrastruktur, Politik, Markt sowie Forschung und Entwicklung aufzeigt.