bluuebunny/crossref_metadata_2025_split huggingface dataset:
Importance of radio-histo-cytopathological correlation, A retrospective study of cyto-histological and radiological correlation of salivary gland lesions using Milan System for Reporting Salivary Gland Cytopathology
Authors: Vijayakumar Gopikrishnan , Narayanan Anand Vijaya , Srikiran T. K , Aravind Sithara , Sandeep Vijay P 
Published: December 2023

ABSTRACT

Background:
Fine-needle aspiration cytology (FNAC) for salivary gland tumors can be challenging to due to the diversity of lesions and cytomorphological convergence between the tumors. The Milan System for Reporting Salivary Gland Cytopathology (MSRSGC) was hence developed and introduced to provide enhanced communication in salivary gland cytopathology. To evaluate the diagnostic utility and validity of MSRSGC in combination with ancillary radiological investigations, we aim to find correlation between Milan system and the radiological impression comparing with final histopathological diagnosis.

Aims and Objective:
Correlate the Milan category with the radiological and final histopathological diagnosis of salivary gland lesions. Review the FNAC diagnosis of salivary gland lesions and identify cytomorphological predictors of malignancy. Correlate the FNAC and the radiological diagnosis with final diagnosis in histopathology.

Material and Methods:
A five year retrospective study, comprising fifty four cases of salivary gland FNAC were included in the study.

Results:
Majority of the cases belong to Milan VI—Malignant followed by Milan IVa—Benign and rest of cases were among other categories. The sensitivity, specificity, positive predictive value, and negative predictive value of adjuvant radiological diagnosis in differentiating benign and malignant salivary gland lesions was found to be 80%, 62.5%, 72.7%, and 71.4%, respectively. We could observe that the concurrent radiological assessment along with Milan system of reporting in salivary gland FNAC especially under suspicious categories (Milan Category IVb as well as Milan Category V) is a useful and sensitive predictor of malignancy.

Conclusion:
A correlation with any form of ancillary radiological assessment is a helpful adjuvant with Milan system to derive a relatable diagnosis in salivary gland neoplasm especially those in categories describing the suspicious entities.
Development and validation of a densitometric high performance thin layer chromatography method for simultaneous analysis of three constituents in Chyavanprash
Authors: Ganguly Partha , Sarkar Rajashree , Saha Sourabh , Chowdhury Subhadeep , Paul Nirankush , Singh Rahul , Katiyar Chandra Kant 
Published: December 2023

Abstract

BACKGROUND:
A densitometric High Performance Thin Layer Chromatography (HPTLC) method has been established for simultaneous quantification of Gallic acid, Piperine, and Withaferin A in Chyavanprash. Chyavanprash possesses multiple health benefits including immunity boosting and has been widely used since ancient times. The surge of COVID-19 has further increased its demand resulting lack of monitoring on raw materials to ensure its efficacy.

METHODS:
Aluminum plates coated with silica gel 60F254 as stationary phase was used with Toluene:Ethyl acetate:Formic acid:Methanol [30:30:8:2] (v/v/v/v) as mobile phase. The plates were developed to a distance of 60 mm at 25 ± 2°C in a chamber previously saturated for 30 min. Densitometric analysis was performed at 254 nm in absorbance mode.

RESULTS:
Amounts of Gallic acid, Piperine, and Withaferin A are 0.75% (w/w), 0.28 % (w/w), and 0.14% (w/w), respectively, in the formulation. The method was validated for specificity, linearity, precision, repeatability, and accuracy. Calibration plots were linear in the concentration range 0.5–6.0 µg per band for Gallic acid; 0.20–1.00 µg per band for Piperine, and 2.0–8.0 µg per band Withaferin A. The correlation coefficients were 0.990, 0.994, and 0.997 for Gallic acid, Piperine, and Withaferin A, respectively.

CONCLUSION:
The method is simple, precise, specific, accurate, and economical. It can be used for routine analysis in formulations containing Amalaki, Pippali, and Ashwagandha.
Pharmacognostical and phytochemical studies of Crotalaria retusa L. (Shanapuspi) dried roots
Authors: Das Debajyoti , Bolleddu Rajesh , Das Manosi , Sahu Dipsundar , Mangal Anupam K. , Babu Gajji , Prasad Peyyala Venkata Vara 
Published: December 2023

Abstract

BACKGROUND:

Crotalaria retusa L. belongs to the Fabaceae family and is found in tropical and subtropical regions of the globe. In Ayurveda, its roots are used against hemoptysis. The roots of C. retusa are used in folklore medicine in many countries for the treatment of numerous diseases. Roots are used against fever, cough, dyspepsia, cardiac disorders, stomatitis, diarrhea, scabies, impetigo, and several other disorders. But so far, the pharmacognostical and phytochemical standardization of root has not been reported for proper identification. Hence, the present study was carried out for the establishment of quality parameters of the root of this plant.

METHODS:
Macroscopy, anatomical studies, powder analysis, physiochemical properties like ash values, extractive values, and high-performance thin layer chromatography profile of roots were done as per Ayurvedic Pharmacopoeia of India guidelines.

RESULTS:
In powder microscopy, acicular crystals, elongated tracheids were observed. Water-soluble and alcohol-soluble extractive values were found to be 4.78% and 7.63%, respectively.

CONCLUSIONS:
The qualitative and quantitative standards established in this study can serve as a valuable authentication source of C. retusa L. roots.
Translation and Validation of the Kannada Version of the Psychosocial Impact of Dental Aesthetics Questionnaire
Authors: Ancy R. J. , Shenoy Rekha P. , Sonde Laxminarayan , Mohammed Imran Pasha 
Published: December 2023

Background:
The Psychosocial Impact of Dental Aesthetics Questionnaire (PIDAQ) is used to evaluate the self-reported impact of dental esthetics on quality of life of adolescents.

Aim:
PIDAQ was not available in Kannada. Prompted by the importance that this type of questionnaire has acquired, this study aimed to translate the original English version of PIDAQ into Kannada and to assess the validity and reliability of the translated Kannada version in order to provide a theoretical basis for further application in Kannada-speaking adolescents.

Materials and Methods:
A school-based descriptive cross-sectional study was conducted among 13–19-year-old adolescents. The study was conducted on a pilot sample (n = 20), and a final study sample (n = 92) was selected conveniently from five different higher secondary schools in Mangalore. PIDAQ was given. Dental esthetics was assessed using the Aesthetic Component of Index of Orthodontic Treatment Need and the Dental Aesthetic Index. Internal consistency was measured using Cronbach’s alpha coefficient. Construct validity was studied by carrying out factor analysis. Test–retest reliability was tested using intra-class correlation coefficient.

Results:
The Kannada PIDAQ showed good reliability with Cronbach’s alpha of 0.832 and overall test–retest reliability ranging from 0.723 to 0.980. The construct validity was good with formation of two new domains “Self-consciousness” and “Aspiration.”

Conclusion:
The good validity and reliability of Kannada PIDAQ make it a suitable tool for assessment of the psychosocial impact of dental esthetics among adolescents who are fluent in reading, writing, and understanding Kannada.
Know Your Adjuncts
Authors: Palliyani Jiti Bhuvandas , Dharmadhikari Suyog , Shetty Devanand , Shetty Arvind , Wadkar Pooja 
Published: December 2023

Introduction:
Knowledge of oral health is a prerequisite for psychological and physical health. The two most prevalent oral diseases, dental caries and periodontal diseases, are largely preventable through professional and self-care activities. With a boom in over-the-counter self-care products available for better oral health, it is imperative to know the awareness with regard to them, among the general population. The objective of this study was to survey the awareness regarding the use of interdental aids and chemical plaque control among the general population.

Materials and Methods:
A questionnaire comprising 17 close-ended questions was handed down to the 473 patients at the outpatient department of DY Patil School of Dentistry, Navi Mumbai, to gather information regarding their awareness and technique of using interdental aids and chemical plaque control. The collected data were statistically analyzed using the SAS software.

Results:
According to the analysis done using the SAS software, 58% lacked awareness of inter dental aids whereas 14% were not aware of mouth rinses. At the same time, 98% had no knowledge about water irrigation devices or the side effects of mouth rinses.

Conclusion:
The study indicated that as compared to oral rinses, the awareness among the masses regarding the use of interdental aids and their helpfulness in prevention of dental caries and periodontal diseases is lacking. There is a need for a dentist to take the front seat in patient education in terms of mechanical and chemical plaque control adjuncts.
Evaluation of Micronuclei in Buccal Smears of Mobile Phone Users: A Comparative Study
Authors: Sangle Varsha , Male Vijayalaxmi P. , Sanap Sneha , Maniyar Anuja , Ugale Gauri , Gundre Dipali 
Published: December 2023

Background:
The mobile uses have been increased drastically, creating increased health concern about radiation effects emitted from mobile phone. Hence, this study aimed to evaluate the micronuclei (MN) frequency in exfoliated oral mucosal cells in high and low mobile users.

Materials and Methods:
The total of 50 subjects was divided into two major groups: low mobile phone users and high mobile phone users. Further, subjects who use mobile phone for more than 10 h a week were considered high talk time users and <4–5 h a week was low talk time users. The buccal mucosa cells are extracted by scraping the oral cavity with a wooden spatula. MN was evaluated in 1000 cells per individual at the microscope.

Results:
There was a significantly increase in MN count in high mobile users compared to low mobile users. There was a highly significant difference in the mean MN count of participants using code division multiple access than global system for mobiles mobile phones. The MN mean count was found to be significantly increased in nonheadphone users in comparison to headphone users. Furthermore, the MN count on the frequently used side of mobile phone was found to be statistically significantly elevated compared to the opposite side.

Conclusions:
Mobile phone radiation, even in the permissible range when used for a longer duration, can cause significant genotoxicity. The genotoxicity is noted when the mobile phone is used more frequently on the same side, which may be due to more amount of radiation and increase in the temperature. Headphone usage reduces the genotoxicity of mobile phone radiation to some extent.
An In vitro, Nonexperimental, Exploratory Research for the Development of a Guidance System to Identify Dental Implant System Used in India Based on Their Radiographic Appearance
Authors: Kute Sayali Ulhas , Agrawal Amit Arvind , Prakash Nilima , Gulve Meenal N. 
Published: December 2023

Introduction:
Identifying an osseointegrated dental implant could become vitally important in case some other clinician tries to restore it and plays a vital role in forensic odontology. However, existing ways to identify them are very crude and nonspecific. In addition, they are not focusing on implants used frequently in India.

Aims:
The aim of this study was to design a guidance system to identify different implant systems and their subtypes used in India and to evaluate the efficiency of this guidance system to identify an unknown dental implant.

Materials and Methods:
Radiographs of the 15 most common dental implant systems used in India were analyzed and categorized based on their morphological appearance under the headings. Nontapered or tapered/threaded or not, neck design, thread length, shape, etc., were observed on intraoral periapical radiographs, and a guidance system in the form of a flow chart was made. Based on the flow chart, 15 randomized assessor-blinded radiographs were tested for the accuracy of the guidance system that was developed. The Chi-square test was used at a 95% confidence interval to determine the accuracy of the guidance system used for the identification of assessor-blinded radiographs.

Results:
The newly designed dental implant identification guidance system effectively identified 14 out of 15 unknown implant radiographs among implant systems and subtypes used in this study. Nonparametric Chi-square test was applied and the results were highly significant (P < 0.05).

Conclusions:
The guidance system developed has the potential to identify the implant system mentioned in this study based on its radiographic appearance.
Clinical Presentation, Management, and Outcomes of Coronavirus Disease 2019 Infection in Children on Active Therapy for Cancer and Posthematopoietic Stem Cell Transplantation: Experience from a Tertiary Care Center
Authors: Kamal Mohammed , Jastaniah Wasil , Abosoudah Ibraheem , Bayoumy Mohammed , Aldajani M. Nawaf , Bahasan Mona , Alseraihy Amal , Elfadul Tahani , Al-Trabolsi Hassan 
Published: December 2023

Abstract

BACKGROUND:
Coronavirus disease 2019 (COVID-19), is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2). Limited data on presentation, management and outcomes of COVID-19 in children with cancer and post-hematopoietic stem cell transplantation (HSCT) from Saudi Arabia is available.

AIM:
The primary aim of the study is to evaluate and describe presenting signs, symptoms, and severity of COVID 19 infection in pediatric patients with cancer and post HSCT, whereas the secondary aims are to assess COVID-19 management strategies and to assess outcomes in terms of treatment delays and mortality.

METHOD:
Retrospective study in children ≤ 14 years of age, who are on-active therapy for cancer or post-HSCT during the period March 2020 to July 2022.

RESULTS:
A total 45 cases with confirmed COVID-19 infection reported in children with cancer and post-HSCT. There were 29 male (64%) and 16 female (36%) cases, and median age of 7 years (1–14 yrs.) at the time of COVID-19 confirmed diagnosis was observed. Acute lymphoblastic leukemia, is the major diagnosis in 18 cases (40%) and all patients on active treatment course with majority of the cases being symptomatic, 78% (n = 35), with fever being the most common reason in 28 cases (80%). Main management was through home isolation in 78%, while hospitalization required in 12 % (10). Primary disease treatment remained uninterrupted in 56% (26), while treatment delays observed in 19 patients (42%). All patients in our study had smooth and complete recovery form COVID-19 infection. At a mean follow-up of 12.0 months (2.0–25.7 months), no morbidities or mortality to report.

CONCLUSION:
Our experience shows mild clinical symptoms and less severe disease course, which is comparable to international experience. Cancer treatment delays emerged as the only major impact, with no impact on the primary cancer progression or relapse at a two-year follow-up seen. Multi-institutional observational studies may enable evaluation of disease-free survival in larger cohort and could address long COVID symptoms in children.
Trends, Topics, and Visualization Analysis of Global Scientific Production on Maternal Mortality from Postpartum Hemorrhage: A 5-year Bibliometric Analysis
Authors: Barja-Ore John , Chavesta Jhonny Jesus Chafloque , Pastuso Pamela Leon , Espinoza-Carhuancho Fran , Mayta-Tovalino Frank 
Published: December 2023

Abstract

BACKGROUND:
Maternal death generates a great impact on public health, and it is recognized that its main cause is postpartum hemorrhage (PPH). Therefore, the objective was to analyze the bibliometric profile of the world scientific production on maternal mortality due to PPH.

MATERIALS AND METHODS:
Bibliometric study that included original articles indexed in Scopus, identified by means of a search strategy that included MESH terms and logical operators. Bibliometric indicators were estimated with the SciVal tool, and the VOSwiever program was used for co-occurrence networks by key terms and co-authorship by country.

RESULTS:
There has been an increase in the number of publications in the past 5 years. Regarding co-occurrence, the most frequent terms were “postpartum hemorrhage” and “maternal mortality.” The United States and the United Kingdom are positioned as those with the highest density of publications; in addition, Australia evidences collaboration with Canada and South Korea. Publications with national collaboration were more frequent (36%). BMC Pregnancy and Childbirth is the most productive journal, although BJOG: An International Journal of Obstetrics and Gynecology has a higher normalized impact. The authors with the highest scientific output belong to an institution in the Netherlands. Vrije Universiteit Amsterdam and Leiden University are the most productive.

CONCLUSION:
Scientific activity on maternal mortality due to PPH is increasing and its main means of dissemination are high-impact journals. National collaboration was more frequent, with the active participation of authors and institutions from the Netherlands and the United States.
Cytotoxicity of Dimethyl Sulfoxide on Human Hematopoietic Stem Cells at Different Temperatures
Authors: Hristova Svetlana H. , Zhivkov Alexandar M. 
Published: December 2023

Abstract

BACKGROUND:
Dimethyl sulphoxide (DMSO, a small strongly polarized amphiphilic molecule) is used as a cryoprotector due to its possibility to easily penetrate cell membranes and to form strong H-bonds with water molecules, preventing by that arising of aqueous crystals.

AIMS:
We have investigated the vitality of hematopoietic stem cells after incubation at +4°C, +20°C and +37°C for 30 min, 60 min and 24 h in cryoprotective solution with 5% DMSO, and also after deep-freezing at –80°C and subsequent storage for 24 hours at –20°C and +4°C.

MATERIALS AND METHODS:
The vitality was evaluated counting the number of alive (uncoloured) and dead stem cells (blue coloured) using a staining test with Trypan blue dye.

RESULTS:
The obtained results disclose that DMSO has a cytotoxic effect which depends on the temperature and the time of cultivation: the cytotoxicity is insignificant at +4°C even for 24 hours; at +37°C about 90% cells remain vital for 1 hour, however after 24 hours they completely die out.

CONCLUSION:
Comparing the non-frozen cells with the deep-frozen at –80°C and subsequently defrozen cells in identical conditions (24 hours storage at +4°C) reveals that the freezing process causes an additional delayed damaging effect, which leads to death of half of the stem cells..
Causes and Management of Tongue Bite in Primary Care
Authors: Chowdhary Tina , Kumar Raman 
Published: December 2023

Abstract
Tongue bite typically refers to an injury to the tongue caused by accidental biting. While it may not be a severe medical emergency, it can cause discomfort and pain. Tongue biting can occur for various reasons, and it is often an accidental and involuntary action. While many tongue bites are minor and can be managed at home, severe or recurrent cases may require a visit to a healthcare professional or dentist for further evaluation. Depending upon the severity of injury, treatment may require first aid to hospital care. In family practice, primary care providers may encounter patients who present with complaints related to tongue bites. Majority of the tongue bite cases can be managed in the community setting itself, however few may require referrals those with severe injury and associated comorbidities such as seizure. Taking preventive measures can help reduce the likelihood of future incidents. Paying attention to situations or habits that may contribute to tongue biting, such as stress, nervous habits, or certain dental issues may be advised to the patients.
To identify the incidence and risk factors of emergence agitation following nasal surgery under general anesthesia: A prospective observational study
Authors: Bhiwal Anil Kumar , Chhabra Alka , Meena Reena , Mandot Purva , Rathore Neha , Chahar Sheetal 
Published: December 2023

Abstract

Background and Aims:
Emergence agitation (EA) is a common condition that occurs during early phase of general anesthesia (GA) recovery. Increased risk of EA is found among ear, nose, and throat procedures and it has been an independent risk factor. The aim of the study is to identify the incidence and risk factors of EA following nasal surgeries.

Methods:
This prospective observational study was performed on 68 patients aged 18–70 years of either sex and American Society of Anesthesiologists (ASA) physical status Grade I-III who underwent GA for elective nasal surgery. The data were collected including age, gender, ASA physical status, pain, duration of surgery, preoperative anxiety level, extubation time, smoking, associated comorbidity, and preoperative use of benzodiazepine. Postoperatively, patients were assessed for emergence delirium by Richmond Agitation Sedation Scale, complications, and pharmacological treatment for EA. The data were analyzed by Student’s t-test, Chi-square test, and binary logistic regression test.

Results:
The incidence of EA was found to be 27.5% (19 patients). EA was found to be significantly associated with preoperative Visual Anxiety Score (P = 0.001), postoperative pain (P = 0.046), male gender (P = 0.015), premedication with benzodiazepine (P = 0.022), ASA physical status (P = 0.0002), and hypertension (P = 0.022). Immediate postoperative complications such as cough, desaturation, laryngospasm, breath holding, and nasal bleeding were found to be statistically significant (P = 0.01) in patients with EA.

Conclusion:
EA is common after nasal surgery under GA and better understanding of potential risks and precipitating factors along with sufficient postoperative pain management may be useful to reduce EA occurrence and consequent postoperative complications.
Fault Diagnosis Algorithm Based on Power Outage Data in Power Grid
Authors: Wang Haiyan , Yuan Xinping , Gao Shanfei , Gao Shoushan 
Published: December 2023

INTRODUCTION: With the rapid development of the power industry, the power system has become more and more complex and prone to failures, which seriously impacts power supply and safety.
OBJECTIVES: Development of efficient and accurate fault diagnosis algorithms for power systems.
METHODS:Proposes a fault diagnosis algorithm based on outage data to construct an outage fault prediction model using accurate data. First, the outage data are collected, pre-processed, feature extracted and reduced to obtain a more efficient data set. Then, an optimized fault diagnosis algorithm is designed based on logit, support vector machine (SVM) and decision tree (DT) to improve the accuracy and efficiency of fault diagnosis.
RESULTS: The method is applied to the natural power system, and the results show that the optimization algorithm outperforms the traditional methods. Specifically, the accuracy of the optimization algorithm can reach 100%, while the accuracy of the traditional logit algorithm and SVM algorithm is only 84% and 93%, which is a significant improvement in the model prediction performance.
CONCLUSION: The author can significantly optimize the performance of its model and construct an outage data mining algorithm with a good predictive ability to achieve grid fault research and judgment, which has a specific application value in the practical field.