bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cr5.7Si2.3P8N24—A Chromium(+IV) Nitridosilicate Phosphate with Amphibole‐Type Structure
Authors: Pointner Monika M. , Fisher Katherine R. , Weidemann Martin , Wolf Florian , Wright Jonathan P. , Bright Eleanor Lawrence , Giacobbe Carlotta , Oeckler Oliver , Schnick Wolfgang 
Published: February 2024

AbstractThe first nitridic analog of an amphibole mineral, the quaternary nitridosilicate phosphate Cr5.7Si2.3P8N24 was synthesized under high‐pressure high‐temperature conditions at 1400 °C and 12 GPa from the binary nitrides Cr2N, Si3N4 and P3N5, using NH4N3 and NH4F as additional nitrogen source and mineralizing agent, respectively. The crystal structure was elucidated by single‐crystal X‐ray diffraction with microfocused synchrotron radiation (C2/m, a=9.6002(19), b=17.107(3), c=4.8530(10) Å, β=109.65(3)°). The elemental composition was analyzed by energy dispersive X‐ray spectroscopy. The structure consists of vertex‐sharing PN4‐tetrahedra forming zweier double chains and edge‐sharing (Si,Cr)‐centered octahedra forming separated ribbons. Atomic resolution scanning transmission electron microscopy shows ordered Si and Cr sites next to a disordered Si/Cr site. Optical spectroscopy indicates a band gap of 2.1 eV. Susceptibility measurements show paramagnetic behavior and support the oxidation state Cr+IV, which is confirmed by EPR. The comprehensive analysis expands the field of Cr−N chemistry and provides access to a nitride analog of one of the most prevalent silicate structures.
Deciphering Oxygen‐Independent Augmented Photodynamic Oncotherapy by Facilitating the Separation of Electron‐Hole Pairs
Authors: Hu Xiaoming , Fang Zhuting , Sun Fengwei , Zhu Caijun , Jia Mingxuan , Miao Xiaofei , Huang Lingting , Hu Wenbo , Fan Quli , Yang Zhen , Huang Wei 
Published: February 2024

AbstractDeveloping Type‐I photosensitizers provides an attractive approach to solve the dilemma of inadequate efficacy of photodynamic therapy (PDT) caused by the inherent oxygen consumption of traditional Type‐II PDT and anoxic tumor microenvironment. The challenge for the exploration of Type‐I PSs is to facilitate the electron transfer ability of photosensitization molecules for transforming oxygen or H2O to reactive oxygen species (ROS). Herein, we propose an electronic acceptor‐triggered photoinduced electron transfer (a‐PET) strategy promoting the separation of electron‐hole pairs by marriage of two organic semiconducting molecules of a non‐fullerene scaffold‐based photosensitizer and a perylene diimide that significantly boost the Type‐I PDT pathway to produce plentiful ROS, especially, inducing 3.5‐fold and 2.5‐fold amplification of hydroxyl (OH⋅) and superoxide (O2−⋅) generation. Systematic mechanism exploration reveals that intermolecular electron transfer and intramolecular charge separation after photoirradiation generate a competent production of radical ion pairs that promote the Type‐I PDT process by theoretical calculation and ultrafast femtosecond transient absorption (fs‐TA) spectroscopy. By complementary tumor diagnosis with photoacoustic imaging and second near‐infrared fluorescence imaging, this as‐prepared nanoplatform exhibits fabulous photocytotoxicity in harsh hypoxic conditions and terrific cancer revoked abilities in living mice. We envision that this work will broaden the insight into high‐efficiency Type‐I PDT for cancer phototheranostics.
Surface functionalization of aramid fibers via constructing different zinc oxide nanostructures for improved UV resistance
Authors: Li Na , Zhou Xinyi , Cao Yutong , Yu Junrong , Wang Yan , Hu Zuming 
Published: February 2024

AbstractAramid fibers (AFs) with high strength and modulus have a vital application in harsh outdoor bulletproof protection and ship ropes; however, solar radiation, especially ultraviolet (UV) radiation, is one of the main factors for affecting their service life. Herein, different zinc oxide (ZnO) nanostructures were constructed on the surface of AFs by the growth of ZnO nanowires (AF‐ZnO NW) and coating of waterborne polyurethane/ZnO nanoparticles composite emulsion (AF/ZnO), respectively. The surface functionalized AFs exhibited enhanced mechanical properties retention after UV radiation. Nevertheless, the tensile strength of AF‐ZnO NW before UV aging was already lower than the tensile strength of original AFs due to the surface structure damage from chemical grafting modification. The tensile strength and elongation retention rates of AF/ZnO‐5% reached 74.4% and 84.4% after UV exposure for 168 h, respectively, which were much higher than the value of 48.3% and 60.5% of the neat AFs. These results provide an effective and low‐cost strategy for improving the UV‐resistance of advanced high‐performance fibers.
Effects of two antioxidants with different degrees of steric hindrance on the thermal‐oxidative aging properties of ABS resin
Authors: Yao Feng‐Hang , Wang Xiao‐Peng , Chen Jie 
Published: February 2024

AbstractABS resin is easily oxidized and deteriorated during use or processing. The addition of antioxidants is an effective method for improving ABS oxidation. The hindered phenol antioxidant DBHMIE and the asymmetrically hindered 245 were added separately or together to ABS; the oxidation induction temperature of ABS increased by 10.6, 12.1 and 14°C, with the addition of DBHMIE, 245 and their combination, respectively, and the initial decomposition temperature T3% increased by 29.7, 16.2 and 51.3°C, respectively. The addition of these two antioxidants to ABS did not greatly affect the mechanical properties of the material, but the impact strength increased by 2.24 kJ/m2 when both antioxidants were added together. During the thermal aging test, the decomposition temperature of the ABS splines prepared with the combined antioxidants increased during the first few cycles. The impact strength of the splines prepared with the combined antioxidants was the highest, with the smallest decrease of only 5.18%. The yellow index of the spline prepared with the combined antioxidants was between those of splines prepared with the antioxidants added alone. The combination of DBHMIE and 245 induced synergistic effects, improved thermal‐oxidative aging resistance, and improved and protected the toughness of ABS resin.
First Nations pre‐LGM ochre processing in Parramatta, NSW, Australia
Authors: Owen Timothy , Munt Simon , Player Sam , Toms Phillip , Wood Jamie 
Published: February 2024

ABSTRACTPrevious archaeological evidence and published analysis has suggested that ochre was first used in the Sydney Basin around 9000 years ago, and that the Parramatta region may not have been occupied by First Nations peoples before ∼14 ka. We present new evidence which firmly places both events before the Last Glacial Maximum (LGM). Multiple ochre fragments, two with microscopically visible evidence of anthropogenic grinding, were recovered from the George Street Gatehouse site within the Parramatta Sand Body (PSB) at Parramatta. The ground ochre was associated with a pit feature buried within the PSB and dated by optically stimulated luminescence (OSL) between ∼35 and 30 ka. This find is the earliest evidence for ochre processing in the Sydney Basin by some 25000 years. A previous model for the region had proposed that occupation prior to and during the LGM was focussed on the Hawkesbury‐Nepean River corridor as a refugium, with only equivocal evidence of occupation prior to ∼14 ka at Parramatta (Williams et al., 2021). We propose that the Parramatta River could also have acted as a refugium for people moving through and occupying the now‐drowned Pleistocene coastal zone; and that those people used ochre in their symbolic expressions.
A Novel Human Interleukin‐23A Overexpressing Mouse Model of Systemic Lupus Erythematosus
Authors: Christodoulou‐Vafeiadou Eleni , Geka Christina , Iliopoulou Lida , Ntari Lydia , Denis Maria C. , Karagianni Niki , Kollias George 
Published: February 2024

ObjectiveInterleukin‐23 (IL‐23) is a crucial cytokine implicated in chronic inflammation and autoimmunity, associated with various diseases such as psoriasis, psoriatic arthritis, and systemic lupus erythematosus (SLE). This study aimed to create and characterize a transgenic mouse model overexpressing human IL‐23A (TghIL‐23A), providing a valuable tool for investigating the pathogenic role of human IL‐23A and evaluating the efficacy of anti–human IL‐23A therapeutics.MethodsTghIL‐23A mice were generated via microinjection of CBA × C57BL/6 zygotes with a fragment of the human IL23A gene, flanked by its 5′‐regulatory sequences and the 3′ untranslated region of human β‐globin. The TghIL‐23A pathology was assessed through hematologic and biochemic analyses, cytokine and antinuclear antibody detection, and histopathologic examination of skin and renal tissues. The response to the anti–human IL‐23A therapeutic agent guselkumab was evaluated in groups of eight mixed‐sex mice receiving subcutaneous treatment twice weekly for 10 weeks using clinical, biomarker, and histopathologic readouts.ResultsTghIL‐23A mice exhibited interactions between human IL‐23A and mouse IL‐23/IL‐12p40 and developed a chronic multiorgan autoimmune disease marked by proteinuria, anti–double‐stranded DNA antibodies, severe inflammatory lesions in the skin, and milder phenotypes in the kidneys and lungs. The TghIL‐23A pathologic features exhibited significant similarities to those observed in human patients with SLE, and they were reversed following guselkumab treatment.ConclusionWe have generated and characterized a novel genetic mouse model of SLE, providing proof‐of‐concept for the etiopathogenic role of human IL‐23A. This new model has a normal life span and integrates several characteristics of the human disease's complexity and chronicity, making it an attractive preclinical tool for studying IL‐23–dependent pathogenic mechanisms and assessing the efficacy of anti–human IL‐23A or modeled disease‐related therapeutics.image
How much freedom does an effectiveness metric really have?
Authors: Moffat Alistair , Mackenzie Joel 
Published: February 2024

AbstractIt is tempting to assume that because effectiveness metrics have free choice to assign scores to search engine result pages (SERPs) there must thus be a similar degree of freedom as to the relative order that SERP pairs can be put into. In fact that second freedom is, to a considerable degree, illusory. That is because if one SERP in a pair has been given a certain score by a metric, fundamental ordering constraints in many cases then dictate that the score for the second SERP must be either not less than, or not greater than, the score assigned to the first SERP. We refer to these fixed relationships as innate pairwise SERP orderings. Our first goal in this work is to describe and defend those pairwise SERP relationship constraints, and tabulate their relative occurrence via both exhaustive and empirical experimentation. We then consider how to employ such innate pairwise relationships in IR experiments, leading to a proposal for a new measurement paradigm. Specifically, we argue that tables of results in which many different metrics are listed for champion versus challenger system comparisons should be avoided; and that instead a single metric be argued for in principled terms, with any relationships identified by that metric then reinforced via an assessment of the innate relationship as to whether other metrics are likely to yield the same system‐versus‐system outcome.
Imperfect and worse than old maintenances for a gamma degradation process
Authors: Corset Franck , Fouladirad Mitra , Paroissin Christian 
Published: February 2024

AbstractThis article considers a condition‐based maintenance for a system subject to deterioration. The deterioration is modeled by a non‐homogeneous gamma process, more precisely the gamma process and the preventive maintenance are imperfect or worse than old. The corrective maintenance actions are as good as new. The maintenance efficiency or non‐efficiency parameters as well as the deterioration parameters are considered to be unknown. The monitoring data under consideration give indirect information on the maintenance parameters. Therefore, an expected maximum algorithm is applied for parameter estimation.
On the Origin of Anode and Cathode Contributions to the Impedance of All‐Solid‐State Batteries
Authors: König Christoph , Ramanayagam Asvitha , Kraus Jennifer , Roling Bernhard 
Published: February 2024

AbstractAll‐solid‐state‐batteries (ASSBs) are considered as promising next‐generation batteries in order to achieve improvements in both energy density and safety. The complex electrochemical processes in ASSBs taking place on different time scales can be probed by means of electrochemical impedance spectroscopy. However, the separation of anode and cathode contributions to the impedance and the understanding of the underlying electrochemical processes in both electrodes is a challenging task. Here, we compare the impedance spectrum of a prototypical full ASSB to those of symmetric cells anode | separator | anode and cathode | separator | cathode. We use Ni‐rich polycrystalline LiNi0.85Co0.10Mn0.05O2 particles as active material inside the composite cathode and an indium‐lithium alloy as anode. Based on the comparison, we show that the charge transfer process inside the cathode is remarkably fast, i. e., even faster than observed for cathodes of batteries with liquid electrolyte. Our results give indication that the differences in the time scales of cathode and anode processes are related to the distinct transport properties of interphases inside the cathode and at the anode | separator interface, respectively.
Monochorionic triplet pregnancy complicated by conjoined twins and early twin–twin transfusion syndrome
Authors: Bustos Juan Carlos , Vera Helga , Ahumada Paz , Martin Daniel 
Published: February 2024

AbstractBackgroundThe condition of monozygotic, monochorionic triplet fetuses with a pair of conjoined twins is extremely rare (close to one in a million births), presents challenges in its management, and with poor prognosis.Case reportWe report a case of monochorionic diamniotic triplet pregnancy, ultrasound at 14 weeks shows a pair of conjoined thoracopagus fetuses, sharing heart, liver, and umbilical cord, in addition to omphalocele. The third fetus, without malformations, presents signs of early heart failure compatible with twin‐to‐twin transfusion syndrome. It was decided to carry out expectant management where at 18 weeks, intrauterine death of the three fetuses occurs. An abortion is performed by hysterotomy.ConclusionsThe treatment in these cases is discussed, three management options have been proposed: expectant management, selective reduction of the conjoined fetuses, or termination of the pregnancy. A review of the literature found only 12 cases with this combination of pathologies, in which only 3 normal fetuses (25%) survived and none of the conjoined twins survived. To our knowledge, this case is the first of a monochorionic triplet pregnancy with conjoined fetuses complicated with early twin‐to‐twin transfusion.
Environmental restoration as a reinforcer in ritualistic contexts
Authors: Anderson Jesse , Kenaston‐Manasseh Lisa 
Published: February 2024

AbstractWe conducted a functional analysis of severe problem behavior (aggression, disruption, and self‐injury). The analysis examined four potential socially mediated functions: attention, escape, receipt of tangible items, and restoration of environmental items. Restoration involved the experimenter replacing missing puzzle pieces, ring stacker rings, and shape sorter blocks without giving the items to the participant. An initial multielement functional analysis, followed by a brief pairwise comparison identified restoration of environmental items as the variable maintaining the participant's problem behavior. Subsequently, we conducted brief functional communication training to teach the participant to mand for restoration of disturbed items in the absence of problem behavior.
Emission enhancement in the luminescence performance of warm red light‐emitting LiSrVO4:Pr3+ phosphors
Authors: Mala V. Rathina , Albert Kavia J. , Princy A. , Kennedy S. Masilla Moses 
Published: February 2024

AbstractWarm red‐emitting praseodymium‐doped LiSrVO4 phosphors were synthesized via solid‐state reaction. The phase formation was verified using an X‐ray diffraction study and the morphology was investigated using a scanning electron microscope study. The LiSrVO4:Pr3+ phosphors emitted red light when exposed to ultraviolet light, indicating their possibility for use in warm white light‐emitting diodes (WLEDs). Furthermore, the effect of charge compensators on the luminescence characteristics was addressed. The decay time was investigated using time‐resolved photoluminescence. Furthermore, thermal quenching was analyzed through temperature‐dependent photoluminescence spectra. Their sensitivity was calculated using temperature‐dependent decay time analysis. The colour purity of the emitted light could be measured by photometric analysis. This comprehensive investigation provides a thorough understanding of the luminescence properties of phosphors for WLED applications.
SLC6A4 gene variants moderate associations between childhood food insecurity and adolescent mental health
Authors: Pilkay S. , Nolasco M. , Nunes S. , Riffer A. , Femia D. , Halevy D. , Veerman T. , Heiland S. , Suwannimit N. , Trexler N. , Gump B. 
Published: February 2024

AbstractBackgroundFood insecurity is a persistent concern in the United States and has been shown to affect child mental health and behavior. The SLC6A4 gene has been indicated as a moderator of the effects of chronic stress on anxiety in adolescents aged 14–21. However, it is unclear if SLC6A4 may also play a role in the effects of childhood food insecurity, a form of chronic stress, on adolescent mental health. This study aimed to identify effects of food insecurity on adolescents’ mental health and delinquent behavior when both mom and child go hungry in the child's early years, and the potential interaction with SLC6A4 variants (SS/LL).MethodsThe data and sample for this research are from the Future of Families and Child Wellbeing Study. The cohort consists of 4898 children (age 1–15 years, male = 47%, African American = 50%) and their respective caregivers sampled from large cities in the United States from 1998 to 2000.ResultsThe SLC6A4 serotonin transporter short/short allele emerged statistically significant as a moderator of childhood food insecurity and adolescent mental health. Specifically, the presence of the short/short allele increased anxiety symptoms in adolescents with exposure to food insecurity in childhood.ConclusionThe SLC6A4 short/short allele amplifies risk of anxiety‐related mental illness when children experience food insecurity. The gene–environment interaction provides insight into the mechanistic pathway of the effects of poverty‐related adversity, such as food insecurity, on developmental trajectories of mental health.
Alterations of amygdala volume and functional connectivity in migraine patients comorbid with and without depression
Authors: Chen Xin , Gui Wei , Li Han‐Li , Deng Zi‐Ru , Wang Yu 
Published: February 2024

AbstractObjectiveThe comorbid relationship between migraine and depression has been well recognized, but its underlying pathophysiology is unclear. Here, we aimed to explore the structural changes of the amygdala and the abnormal functional connectivity of the centromedial amygdala (CMA) in migraineurs with depression.MethodsHigh‐resolution T1‐weighted and functional magnetic resonance images were acquired from 22 episodic migraineurs with comorbid depression (EMwD), 21 episodic migraineurs without depression (EM), and 17 healthy controls (HC). Voxel‐based morphometry and resting‐state functional connectivity (rsFC) were applied to examine the intergroup differences in amygdala volume.ResultsThe bilateral amygdala volume was increased in the EMwD and EM groups compared with the HC group, but there were no differences between the EMwD and EM groups. The right CMA exhibited decreased rsFC in the left dorsolateral prefrontal cortex (DLPFC) in the EMwD group compared with the EM group, while rsFC increased between the CMA and the contralateral DLPFC in the EM group compared with the HC group. In addition, the EM group showed decreased rsFC between the left CMA and the left pallidum compared with the HC group.ConclusionsEnlarged amygdala is an imaging feature of EM and EMwD. The inconsistency of rsFC between CMA and DLPFC between migraineurs with and without depression might indicate that decreased rsFC between CMA and DLPFC is a neuropathologic marker for the comorbidity of migraine and depression. The core regions might be a potential intervention target for the treatment of EMwD in the future.
Penalized canonical correlation analysis reveals a relationship between temperament traits and brain oscillations during mind wandering
Authors: Heinilä Erkka , Hyvärinen Aapo , Parkkonen Lauri , Parviainen Tiina 
Published: February 2024

AbstractIntroductionThere has been a growing interest in studying brain activity under naturalistic conditions. However, the relationship between individual differences in ongoing brain activity and psychological characteristics is not well understood. We investigated this connection, focusing on the association between oscillatory activity in the brain and individually characteristic dispositional traits. Given the variability of unconstrained resting states among individuals, we devised a paradigm that could harmonize the state of mind across all participants.MethodsWe constructed task contrasts that included focused attention (FA), self‐centered future planning, and rumination on anxious thoughts triggered by visual imagery. Magnetoencephalography was recorded from 28 participants under these 3 conditions for a duration of 16 min. The oscillatory power in the alpha and beta bands was converted into spatial contrast maps, representing the difference in brain oscillation power between the two conditions. We performed permutation cluster tests on these spatial contrast maps. Additionally, we applied penalized canonical correlation analysis (CCA) to study the relationship between brain oscillation patterns and behavioral traits.ResultsThe data revealed that the FA condition, as compared to the other conditions, was associated with higher alpha and beta power in the temporal areas of the left hemisphere and lower alpha and beta power in the parietal areas of the right hemisphere. Interestingly, the penalized CCA indicated that behavioral inhibition was positively correlated, whereas anxiety was negatively correlated, with a pattern of high oscillatory power in the bilateral precuneus and low power in the bilateral temporal regions. This unique association was found in the anxious‐thoughts condition when contrasted with the focused‐attention condition.ConclusionOur findings suggest individual temperament traits significantly affect brain engagement in naturalistic conditions. This research underscores the importance of considering individual traits in neuroscience and offers an effective method for analyzing brain activity and psychological differences.