bluuebunny/crossref_metadata_2025_split huggingface dataset:
Increased flexibility of CA3 memory representations following environmental enrichment
Authors: Ventura Silvia , Duncan Stephen , Ainge James A. 
Published: October 2023

SummaryEnvironmental enrichment (EE) improves memory, particularly under conditions of high memory interference1–6. Here, we investigate the neural mechanisms facilitating improved memory following EE. Using associative recognition memory tasks that model the automatic and integrative nature of episodic memory, we find that EE-dependent improvements in difficult associative memory discriminations are related to increased adult hippocampal neurogenesis and sparser memory representations across the hippocampus. Additionally, by recording CA3 place cells as enriched and standard-housed rats explored the increasingly distinct shapes of a “morph” box, we report for the first time that EE changes the way CA3 place cells discriminate similar contexts. CA3 place cells of enriched rats show greater spatial tuning, increased firing rates, and enhanced remapping to contextual changes. These findings point to more precise and flexible CA3 memory representations in enriched rats. Increased spatial tuning and flexibility might support the well-established EE-dependent improvements in fine memory discrimination.HighlightsEE improves discrimination of similar associative memoriesEE-dependent memory improvements are related to increased adult neurogenesisEE results in sparser hippocampal activityEE increases spatial tuning, firing and remapping of CA3 place cells
TheListeria monocytogenespersistence factor ClpL is a potent stand-alone disaggregase
Authors: Bohl Valentin , Hollmann Nele Merret , Melzer Tobias , Katikaridis Panagiotis , Meins Lena , Simon Bernd , Flemming Dirk , Sinning Irmgard , Hennig Janosch , Mogk Axel 
Published: October 2023

AbstractHeat stress can cause cell death by triggering the aggregation of essential proteins. In bacteria, aggregated proteins are rescued by the canonical Hsp70/AAA+ (ClpB) bi-chaperone disaggregase. Man-made, severe stress conditions applied during e.g. food-processing represent a novel threat for bacteria by exceeding the capacity of the Hsp70/ClpB system. Here, we report on the potent autonomous AAA+ disaggregase ClpL fromListeria monocytogenesthat provides enhanced heat resistance to the food-borne pathogen enabling persistence in adverse environments. ClpL shows increased thermal stability and enhanced disaggregation power compared to Hsp70/ClpB, enabling it to withstand severe heat stress and to solubilize tight aggregates. ClpL binds to protein aggregates via aromatic residues present in its N-terminal domain (NTD) that adopts a partially folded and dynamic conformation. Target specificity is achieved by simultaneous interactions of multiple NTDs with the aggregate surface. ClpL shows remarkable structural plasticity by forming diverse higher assembly states through interacting ClpL rings. NTDs become largely sequestered upon ClpL ring interactions. Stabilizing ring assemblies by engineered disulfide bonds strongly reduces disaggregation activity, suggesting that they represent storage states.
Increasing green leafy vegetable consumption through street food dishes in Lagos, Nigeria
Authors: Raaijmakers Ireen , Dijkxhoorn Youri , Snoek Harriette , Amoreoluwa Kikelomo , Adeboye Adedola , Talabi Olufolajimi , Plaisir Christine , Okoruwa Augustine Ehimen , Toye Oluwole , van Wagenberg Coen 
Published: October 2023

PurposeDespite its health benefits, vegetable consumption is low in urban Nigeria. Interventions have been successful in increasing urban Nigerians' vegetable intake in the home environment, but interventions doing so for popular out-of-home consumption are lacking. This study aimed to design, implement and assess an intervention to increase the vegetable intake of urban Nigerians through street foods.Design/methodology/approachA quasi-experimental design was applied in Lagos, Nigeria. During the intervention, 12 trained street food vendors (SFVs) actively promoted the health benefits of vegetables to their customers (using marketing statements and posters) and provided the option to buy an additional green leafy vegetables (GLVs) side dish to their meal. Purchases were observed, and a survey was conducted before and during the intervention to measure perceived meal quality and satisfaction. Six to eight weeks after the intervention, a mystery shopper visited the vendor to assess if they were still selling additional GLVs.FindingsAlmost half (46%) of the 1,506 observed customers bought additional GLVs during the intervention. Both at baseline (N = 452) and during intervention (N = 564), meal satisfaction was high. Users were on average more educated and older than non-users. Most vendors did not perceive the sale of additional GLVs as additional work. Six to eight weeks after the intervention, nine vendors (75%) were still selling additional GLVs.Originality/valueThis study showed that SFVs informing consumers on the potential health benefits of vegetables and offering these vegetables in street food dishes at a commercially viable price is an interesting option to increase vegetable intake.
Sustainability communication: how to communicate an inconvenient truth in the era of scientific mistrust
Authors: Voci Denise , Karmasin Matthias 
Published: October 2023

PurposeThis conceptual paper aims to explore the current state of sustainability communication research, focusing on the challenges of communicating inconvenient truths in an era of scientific mistrust. Therefore, this study aims to (1) examine the existing research landscape in sustainability communication, (2) identify unresolved problems and challenges, and (3) propose strategies for counteract misinformation through targeted communication.Design/methodology/approachFor this, the authors conducted a critical literature review and analyzed the resulting sample (n = 473 journal articles) by means of qualitative content analysis to (1) evaluate existing communication approaches dealing with the communication of sustainability's inconvenient truth, (2) identify stakeholder groups involved in sustainability communication, (3) discuss limitations of current communication approaches and (4) present recommendations on (more) effective communication strategies to address the unresolved issues in sustainability communication.FindingsThe analysis reveals that when it comes to sustainability communication and its unresolved problems, literature refers to four key stakeholder groups: (1) science deniers; (2) adaptation skeptics; (3) whitewashers and (4) world saviors. Furthermore, the analysis provides valuable insights into the complex dynamics involved in communicating sustainability, emphasizes the need for tailored approaches to engage and address the concerns of each stakeholder group, and exposes limitations in current communication methods and approaches. Accordingly, the analysis highlights the necessity of developing new theories, models and methods specific to sustainability communication to tackle its unique challenges effectively.Research limitations/implicationsLike our society, communication sciences need a fundamental transformation to meet sustainability communication's new challenges induced by the necessary shift toward sustainable development.Originality/valueThis paper provides a comprehensive overview of the current state of sustainability communication in research, specifically addressing the challenges of effectively communicating unpleasant news in the context of scientific mistrust. It fills a gap in existing literature by examining the progress made in addressing these issues and identifying the emerging challenges that need to be addressed.
Do entrepreneurs mistreat probationary employees? The mediating role of perceived ethical climate and moderating roles of core job characteristics
Authors: Jang Yongseok , Zhang Jing , Zheng Dianhan 
Published: October 2023

Purpose
Recent high-profile ethical scandals in start-up organizations have made people wonder whether entrepreneurship may cultivate a work environment with less emphasis on ethics. This study examined a psychological process about how an organization’s entrepreneurial orientation (EO) can affect its treatment of probationary employees, a vulnerable yet understudied group of workers.

Design/methodology/approach
The authors recruited 241 participants through Amazon Mechanical Turk. They answered an online survey about their experiences as probationary employees.

Findings
This study found that job feedback and meaning moderated the relationship between EO and ethical climate, such that this relationship was statistically significant and positive only among participants who reported high levels of feedback and job meaning. Ethical climate, in turn, was found to be related to a reduction in workplace incivility experienced by probationary employees. The indirect effect of EO on incivility via ethical climate was contingent on job feedback and meaning.

Research limitations/implications
This study extends the discussion on the entrepreneurial context, adds to EO literature with findings on its indirect effect on nonfinancial performance and reinforces institutional theory through job characteristics’ moderating roles. However, a methodological limitation is conducting a cross-sectional single-source survey due to limited access to firms and probationary employees, considering the hidden population involved.

Practical implications
This study found no evidence of probationary employee exploitation in high EO organizations. Job seekers should embrace probationary work at start-ups. Entrepreneurial leaders should balance being proactive, innovative and caring toward employees.

Originality/value
It is debatable whether entrepreneurship leads to unethical organizational conduct. By studying a vulnerable group of employees, the authors discovered that EO, when paired with favorable job design factors, can create a more ethical workplace where temporary talents are treated with dignity and respect.
Achieving biodiversity net gain by addressing governance gaps underpinning ecological compensation policies
Authors: Rampling Emily E. , zu Ermgassen Sophus O. S. E. , Hawkins Isobel , Bull Joseph W. 
Published: October 2023

AbstractBiodiversity compensation policies have emerged around the world to address the ecological harms of infrastructure expansion, but historically compliance is weak. The Westminster government is introducing a requirement that new infrastructure developments in England demonstrate they achieve a biodiversity net gain (BNG). We sought to determine the magnitude of the effects of governance gaps and regulator capacity constraints on the policy's potential biodiversity impacts. We collated BNG information from all new major developments across six early‐adopter councils from 2020 to 2022. We quantified the proportion of the biodiversity outcomes promised under BNG at risk of noncompliance, explored the variation in strategies used to meet developers’ biodiversity liabilities, and quantified the occurrence of simple errors in the biodiversity metric calculations. For large developments and energy infrastructure, biodiversity liabilities frequently met within the projects’ development footprint. For small developments, the purchase of offsets was most common. We estimated that 27% of all biodiversity units fell into governance gaps that exposed them to a high risk of noncompliance because they were associated with better‐condition habitats delivered on‐site that were unlikely to be monitored or enforced. More robust governance mechanisms (e.g., practical mechanisms for monitoring and enforcement) would help ensure the delivery of this biodiversity on‐site. Alternatively, more biodiversity gains could be delivered through off‐site biodiversity offsetting. For the latter case, we estimated that the demand for offsets could rise by a factor of 4; this would substantially increase the financial contributions from developers for conservation activities on private land. Twenty‐one percent of development applications contained a simple recurring error in their BNG calculations. One‐half of these applications were approved by councils, which may indicate under‐resourcing in council development assessments. Our findings demonstrate that resourcing and governance shortfalls risk undermining the policy's effectiveness.
The Puzzle of Belief Requires an Evolutionary Key to be Solved
Authors: Blancke Stefaan 
Published: October 2023

AbstractThe puzzle of belief arises as currently no definition captures the various ways in which people believe. As a solution to this puzzle and to make the study of belief empirically tractable, Van Leeuwen and Lombrozo suggest acknowledging the plurality of beliefs and organizing beliefs according to their shared functions and traits. However, their proposal does not make yet the distinction between proper and derived functions of belief‐generating cognitive systems. For that, we need a theoretical perspective anchored in evolutionary thinking. Such a perspective allows us to recognize the adaptive problems belief‐generating cognitive systems solve and what sorts of beliefs they will tend to produce. By analyzing beliefs based on evolutionary considerations, we not only make the puzzle of belief empirically tractable, but also take an important step toward solving it.
Evidence for a Weak but Reliable Processing Advantage for False Beliefs Over Similar Nonmental States in Adults
Authors: Samuel Steven , Cole Geoff G. , Eacott Madeline J. , Edwardson Rebecca , Course Hattie 
Published: October 2023

AbstractThe ability to understand the mental states of others has sometimes been attributed to a domain‐specific mechanism which privileges the processing of these states over similar but nonmental representations. If correct, then others’ beliefs should be processed more efficiently than similar information contained within nonmental states. We tested this by examining whether adults would be faster to process others’ false beliefs than equivalent “false” photos. Additionally, we tested whether they would be faster to process others’ true beliefs about something than their own (matched) personal knowledge about the same event. Across four experiments, we found a small but reliable effect in favor of the first prediction, but no evidence for the second. Results are consistent with accounts positing specialized processes for (false) mental states. The size of the effect does, however, suggest that alternative explanations such as practice effects cannot be ruled out.
Therapy of necrobiotic xanthogranuloma – case series and review of the literature
Authors: Hansen Inga , Ghandili Susanne , Abeck Finn , Booken Nina , Schneider Stefan W. 
Published: October 2023

SummaryNecrobiotic xanthogranuloma is a rare disease that is part of the non‐Langerhans cell histiocytoses. It is characterized by yellowish skin lesions, which are typically periorbitally localized. Extracutaneous manifestations of all organs are possible and can cause potentially life‐threatening complications. The disease also belongs to the facultative paraneoplasias and is often associated with paraproteinemia. These aspects should be considered regarding further diagnostics. Due to the rarity of the disease, there are no standardized guidelines for therapy so far. The combination of prednisolone and chlorambucil as well as intravenous immunoglobulins seem to be effective therapeutic options. We present four cases from our clinic as well as the current results of the literature in this mini‐review and would like to highlight the therapeutic challenge as well as the need for the development of guidelines.
Simulating the Spatial Extent of Thermally Enhanced Reaction Zones for Low Temperature Thermal Treatment
Authors: Xie Qianli , Mumford Kevin G. , Kueper Bernard H. 
Published: October 2023

AbstractLow temperature thermal treatment (LTTT) is a technology that can enhance aqueous‐phase degradation reactions for organic constituents in groundwater. Understanding heat transfer in groundwater is important for the design of LTTT applications. In this study, the effect of permeability heterogeneity on temperature distributions during and after the application of heat was investigated by numerical modeling. An enhanced reaction zone was determined for the hydrolysis of 1,1,1‐trichloroethane (1,1,1‐TCA) using an average half‐life considering the temperature history during and after heating. For hydrolysis reactions, the average half‐life could be reduced substantially by reaching a high temperature for a short period of time because their reaction rates increase exponentially with increased temperatures. Results showed that the enhanced reaction zone was shifted downstream of the heater well zone at high groundwater velocities. This suggests that heaters should be shifted upstream of the target treatment zone to fully utilize the applied heat. In addition, permeability heterogeneity leads to greater macroscopic dispersion at higher velocities. This resulted in higher spreading of heat and faster heat dissipation in the simulations with a heterogeneous permeability condition compared with a homogenous permeability condition. As a result, the enhanced reaction zone was smaller in simulations with higher levels of permeability heterogeneity at a mean velocity of 0.3 m/day.
An evaluation of the customized nasal clip protocol for bilateral cleft lip and palate presurgical infant orthopaedics
Authors: Hendricks Heather , Lypka Michael , Jiang Shao 
Published: October 2023

AbstractObjectivesNasoalveolar moulding (NAM) has resulted in profound outcomes in the treatment of bilateral cleft lip and palate patients, including non‐surgical columellar lengthening and nasal moulding. We examine an innovative alternative that is less invasive, yet provides similar results.In this study, we describe a novel approach using the Customized Nasal Clip Protocol (CNCP™) and compare the treatment outcomes of a small cohort of infants with bilateral cleft lip ± palate with published results of the Grayson nasoalveolar moulding protocol.Materials and MethodsA cohort of six bilateral‐cleft‐affected patients was evaluated for this study. Standardized frontal and worm's eye view photographs were obtained, and clinical measurements were utilized to garner columellar length measurements and nostril height comparisons. The initial and post‐surgical results were statistically compared with a student's t‐test (p < .05). Inclusion and exclusion criteria were applied to the cohort, which will be described.ResultsThe resulting columellar length and nostril height increases of the CNCP™ group were comparable to a published cohort of subjects that have undergone nasoalveolar moulding. The nasal changes were found to be significant with a p‐value <.01. The CNCP™ cohort also had fewer clinic visits, no complications that led to complete pauses of active treatment, and the benefit of receiving comprehensive treatment that was initiated at their first clinical presentation, in comparison to traditional NAM patients.ConclusionThe increase of columellar length and nostril height that resulted from utilizing the CNCP™ in bilateral cleft patients met the treatment goals of presurgical infant orthopaedics, with results on par with published results of NAM. These results, paired with the reduction in patient, family, and provider burden, further support the continued use and development of the CNCP™ for appropriate patient populations.
Memory lapses during a pandemic: Differential associations between COVID‐stress and daily memory lapses?
Authors: Jeong Mijin , Turner Jennifer , Greaney Jody , Darling Ashley , Ferguson Giselle , Scott Stacey , Jang Heejung , Mogle Jacqueline 
Published: October 2023

AbstractThe policies related to COVID‐19 pandemic such as stay at home orders and social distancing increased daily stress and associated impairments in mental health. This study examines the association between COVID‐related stress and cognitive functioning by examining two different types of daily memory lapses, those related to prospective memory (i.e., memory for future plans) and retrospective memory (i.e., memory for past information) as well as the perceived emotional and functional consequences of daily memory problems. As part of a larger study, 58 adults (18 men; 22 ± 3 years) completed a web‐based version of the daily inventory of stressful events including stress related to COVID‐19 and positive/negative affect for eight consecutive days between 8 September 2020 and 11 November 2020. Findings showed that prospective lapses were positively correlated with COVID‐19 stressors (r = 0.41, p = 0.002). At the within‐person level, daily COVID‐19 stressors were significantly associated with the number of prospective lapses (b = 0.088, SE = 0.040). COVID‐19‐related stressors were not significantly related to retrospective lapses (all ps > 0.05). Our findings suggested that more daily COVID‐19 stressors were related to greater numbers of prospective lapses in daily life even among healthy younger adults. Thus, future research should address long term relations of COVID‐19 stress and cognitive functioning in addition to the specific cognitive impairments related to COVID‐19 infection.
A Novel Framework for Accelerated Characterization of Pyrolysis Kinetics of High-Temperature Composites Using Theory-Guided Probabilistic Machine Learning
Authors: Portales Picazo Paulina , Gray Alexander , Zobeiry Navid 
Published: October 2023

Abstract
Establishing a relationship between processing conditions during the manufacturing process and end-part properties is essential for the efficient fabrication of advanced composites. For fiber-reinforced polymer composites, this manufacturing process typically includes multiple complex stages such as lay-up, curing, high-temperature pyrolysis, several resin backfill steps followed by pyrolytic process repeats, and graphitization. In particular, the high-temperature pyrolysis step is critical, because the process temperature cycle significantly affects the degradation reactions and phase transformations undergone by the polymer resin. Therefore, it is crucial to identify the ideal parameters for optimal performance. Characterizing pyrolysis kinetics to achieve this commonly requires an exhaustive testing campaign to study the effect of different temperature cycles on final properties. This involves thousands of possible combinations of multi-heating ramps and holds, resulting in an intractable search space. Additionally, established literature succeeds in characterizing the pyrolysis kinetics for simple dynamic temperature cycles, but fails to account for the effect of more complex cycles. This paper aims to address the above challenges by introducing a novel probabilistic machine learning-based framework for accelerated characterization of pyrolysis kinetics using theory-based transformations of limited and noisy experimental data. The degradation reactions and fraction of volatile components of a polymer-based composite are studied using thermogravimetric analysis techniques, and results are analyzed using theory-guided Gaussian Processes (GPs) to accurately characterize the pyrolysis kinetics of complex temperature cycles. The framework is then used to identify optimal parameters for achieving the desired yield. Using this approach, the experimental effort is considerably reduced while developing an accurate pyrolysis kinetics model for the material and establishing optimal processing parameters.