bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Kimia dan Mikrobiologi Dadiah yang diperkaya Ekstrak Kulit Manggis (Garcinia mangostana L.): Peluang Produk Fermentasi Sehat
Authors: Jannah Hidayatul , Endra Pratama Yudha , Refi Anggraini Okta , Fatdillah Haezah , Sarly Riani Uci , Febi Febi , Putri Kharisma 
Published: February 2025

Dadiah merupakan sumber daya lokal yang berasal dari daerah Sumatera Barat, terbuat dari susu kerbau yang difermentasi selama 24-48 jam di dalam tabung bambu secara anaerob. Pada penelitian ini dilakukan penambahan ekstrak kulit manggis ke dalam dadiah yang diharapkan dapat meningkatkan kualitas dari dadiah sebagai pangan fungsional sumber probiotik dan juga antioksidan. Penelitian ini menggunakan Rancangan Acak Lengkap dengan 3 kali ulangan berupa penambahan ekstrak kulit manggis sebanyak 0%, 1%, 2%, dan 3%. Hasil penelitian menunjukkan bahwa penambahan ekstrak kulit manggis ke dalam dadiah berpengaruh nyata (P<0.05) terhadap kadar air 83,87-85,04%, kadar lemak 4,68-7,34%, TPC 16,20-23,90 x 105 CFU/ml, dan tidak berpengaruh nyata (P>0.05) terhadap kadar protein 4,85-6,21% serta total BAL 3,75-8,95 x 109 CFU/ml. Dari hasil penelitian dapat disimpulkan bahwa penambahan ekstrak kulit manggis ke dalam dadiah sebanyak 2% mempertahan dan meningkatkan kualitas dadiah.
Enkapsulasi dengan Metode Ioniglasik dalam Additive Pakan ditinjau dari Produktivitas Ayam Broiler
Authors: Ambarwati Lilis , Marsudi Marsudi , Ina T Nur , Novianti Novianti , Basri Basri 
Published: February 2025

Enkapsulasi merupakan salah satu metode untuk melindungi zat aktif dalam suatu bahan pakan agar tidak mengalami kerusakan akibat perubahan temperatur dan pH pada organ pencernaan, sehingga akan meningkatkan performa dan kesehatan ternak. Metode ioniglasik merupakan teknik enkapsulasi untuk melindungi zat aktif dapat sampai target sasaran pada usus halus sehingga dapat dicerna secara efisien. Buah buni dan soppeng memiliki antioksidan yang tinggi dan mengandung flavonoid dapat menjadi additive alami dalam pakan. Tujuan penelitian ini adalah mengevaluasi penggunaan teknik enkapsulasi dengan penambahan citosan udang dan STTP pada pakan. Bahan yang digunakan adalah 120 DOC umur 1 hari dari PT. Charoen Pokphand dengan strain cobs, berat 48 g, buah buni, buah soppeng, citosan, trypholypsopat, asam sitrat, peralatan seperti kandang metabolis 120 unit, tempat pakan, tempat minum, termohigrometer dan recording. Percobaan terdiri dari 4 perlakuan dan 6 ulangan dengan masing-masing ulangan terdiri dari 5 ekor. Perlakuan terdiri atas P0= pakan komersil (kontrol), P1= pakan komersil + 1% enkapsulasi buni, P1 = pakan komersil + 1% enkapsulasi soppeng, dan P3 = pakan komersil + 1% enkapsulasi buni dan soppeng. Parameter yang diamati tampilan terdiri atas konsumsi ransum, efisiensi ransum, pertambahan berat badan harian, berat karkas serta berat lemak abdominal ayam broiler. Hasil percobaan menunjukan bahwa penambahan enkapsulasi buni dan soppeng berpengaruh signifikan (P<0,05) terhadap efisiensi ransum, PBBH, berat karkas serta lemak abdominal namun belum berpengaruh signifikan terhadap konsumsi ayam broiler. Teknik enkapsulasi buah buni dan soppeng dengan level 1% pada perlakuan P3 memiliki produktivitas terbaik dan dapat digunakan sebagai feed additive dalam ransum ayam broiler.
Nilai Pertumbuhan dan Produksi Turi (Sesbania glandiflora) Fase Awal pada Aplikasi Bahan Organik dari Feces Ternak yang Telah diperkaya
Authors: Neonnub Jefrianus 
Published: February 2025

Tujuan dari penelitian ini adalah untuk mengetahui nilai pertumbuhan dan produksi awal tanaman turi yang diberi perlakuan bokashi berbahan dasar feses ternak berbeda. Penelitian ini dilaksanakan selama 2 bulan, dimulai dari September sampai November 2021 bertempat di kebun percobaan Fakultas Pertanian Universitas Timor, Kelurahan Sasi, Kecamatan Kota Kefamenanu, Kabupaten Timor Tengah Utara. Metode yang digunakan dalam penelitian ini Metode Eksperimen menggunakan Rancangan Acak Lengkap (RAL) yang terdiri dari 4 perlakuan dan 4 ulangan sehingga terdapat 16 unit satuan percobaan. Perlakuan yang diuji terdiri dari R0: tanpa bokashi (Kontrol); R1: Bokashi feses ayam; R2: Bokashi feses sapi; R3: Bokashi feses kambing. Variabel yang diamati terdiri dari Tinggi tanaman (cm), Diameter batang (cm), Jumlah tangkai daun dan Berat segar Tanaman (gr) Hasil penelitian menunjukan pemberian pupuk Bokashi padat berbahan dasar Feses berbeda berpengaruh nyata (P<0.05) terhadap pertumbuhan dan produksi awal turi dimana aplikasi bokashi berbahan dasar feces kambing menghasilkan tinggi tanaman (18,21 cm), Diameter batang (0,44 mm), jumlah tangkai daun (9,04 tangkai) dan Berat segar tanaman (36,37gram). Disimpulkan bahwa penggunaan bokashi berbahan dasar feces berbeda dapat meningkatkan pertumbuhan dan produksi awal turi.
Vitamin D Levels in Chronic Kidney Disease: A Cross-Sectional Study Conducted in Community Based Medical College, Bangladesh (CBMC,B) Hospital
Authors: Hasan Mahmud Javed , Ray Nitai Chandra , Morshed Syed Mahbub , Helal ASM Julfekar , Ahmed Faruque , Afrin Nahid , Shahrin Sabrina , Alam Md Iftakharul 
Published: February 2025

Patients with chronic kidney disease (CKD) have a high prevalence of vitamin D deficiency; such a deficiency can exacerbate the CKD and related complications. The population in Bangladesh gets exposure to sunlight radiation; however, levels of vitamin D levels could be affected due to factors like skin color, dressing etiquette, etc. This cross-sectional study was done in Community Based Medical College, Bangladesh (CBMC,B) Hospital, from January 2021 to January 2022, to determine the prevalence vitamin D deficiency among of CKD patients and to examine association between vitamin D and CKD classification. A total of 120 patients who had been diagnosed with CKD (stages 3-5) were included in this study. Data on age, gender, past medical history, and blood samples for serum creatinine and 25-hydroxyvitamin D levels were obtained. The eGFR was estimated from the CKD-EPI formula. Serum (>30 ng/mL) levels were classified into a normal range, which was greater than 30 ng/mL, insufficient, between 10 and 30 ng/mL, and deficient if lower than 10 ng/mL. The mean age of the study participants was 53.25±7.6 years, with 66.7% male. Vitamin D deficiency was found in 25% of patients, while 35.8% had insufficiency. A significant inverse relationship was observed between CKD stages and mean vitamin D levels (p<0.00001). Mean vitamin D levels decreased from 33.53±6.24 ng/mL in stage 3a to 12.36 ± 3.43 ng/mL in stage 5. Our study gives an indication that vitamin D deficiency and insufficiency are considerable among the CKD patients in Bangladesh, and it correlates significantly with the severity of kidney disease. Hence, we recommend vitamin D monitoring and possibly supplementation in the context of CKD, especially in the late stages.
CBMJ 2025 January: Vol. 14 No. 01 P: 4-10
Adoption of Contraceptive Methods among Eligible Couples in a Rural Area of Mymensingh District, Bangladesh
Authors: Hasan AHM , Begum Maksuda , Dipu Sultana Sobnum , Saha Kamana Rani , Islam Md Shahidul , Ali Md Yunus 
Published: February 2025

Contraceptive prevalence influences fertility which in turn influences socioeconomic growth, health care especially maternal and child health (MCH) care and quality of life. This cross-sectional, descriptive study was conducted in Churkhai village under Mymensingh district, Bangladesh, between December 2021 and April 2022, to estimate the prevalence of adoption of different contraceptive methods among eligible couples. Study population was eligible couples of a rural area. Purposively selected sample size was 180. Data were collected on a predesigned questionnaire by direct interviewing women of reproductive age group. Data entry was done in an MS-Excel sheet and analysis was done by SPSS version 20.0. Age of respondents ranged from 17 years to 49 years. The mean age was 28.90±7.70 years. The majority of respondents (96.67%) were housewives and 21.11% respondents were illiterate. We found that contraceptive prevalence among eligible couples was 85%, while total fertility rate (TFR) was 2.2. Contraceptive prevalence was more (63.33%) among female respondents in comparison to male (21.67%). Contraceptive prevalence was influenced by participants’ age (highest between 25 and 34 years), religion and caste (100 percent among Hindus), occupation (100 percent among service holders and business professionals), socioeconomic condition and female literacy. Adoption of different methods included oral contraceptive pill (OCP) (50%), hormone injection (8.89%), intrauterine contraceptive device (IUCD) (1.11%), hormonal implant (1.11%), tubal ligation (2.22%), male condom (21.11%) and non-scalpel vasectomy (NSV) (0.56%). Temporary methods (82.22%) were much more accepted than that of permanent methods (2.78%). Our data suggests that using contraceptives for spacing method is much more popular than that of long acting and permanent methods among eligible couples. Contraceptive and reproductive education and better socio-economic condition can play an important role in use of contraceptive methods.
CBMJ 2025 January: Vol. 14 No. 01 P: 28-33
Menopausal Symptoms and Coping Strategies among Women of 40-60 Years Age-Group: A Tertiary Care Hospital Experience from Bangladesh
Authors: Zahan Akter , Sharma Netay Kumer , Islam Md Nazrul , Sen Shila , Bhowmik Kingkon Rani 
Published: February 2025

A cross-sectional, descriptive study was conducted, in the Department of Obstetrics & Gynaecology, of Community Based Medical College, Bangladesh (CBMC,B) Hospital, Mymensingh, Bangladesh, on 120 women aged between 40 and 60 years to assess their menopausal symptoms and coping strategies. Exclusion criteria included pregnancy, breastfeeding, or any other significant medical conditions. A semi-structured, pre-tested questionnaire based on modification of Menopausal Rating Scale (MRS) was used to assess their demographic characteristics, menopausal symptoms, and coping strategies, e.g., exercise and dietary adjustments. We also examined BMI of the participants. Participants were categorized based on menopausal status: 46.67% premenopausal, 31.67% perimenopausal, and 21.66% postmenopausal. Graduates represent the most significant education group (34%). Marriage (46.67%), widowhood (29.16%), and divorce (15.83%) are common marital statuses. Economic status varies, with the middle category prevalent (30.70%) and lower status at 14.70%. In BMI, most of the participants were found overweight (42%) or obese (27%). Menopausal symptoms include joint/muscle discomfort (70.60%), exhaustion (61.30%), and sleeping problems (59.30%). Coping strategies include self-calming (76%), exercise, diet awareness (69%), social relationships (63%), sense of achievement (38%), and creative activities (46%). Significant p-values were observed among the groups in self-calming skill, social relationship, and sense of achievement (p<0.05), but not in awareness about diet and weight and doing creative activities (p>0.05). Our data suggests that some women may start experiencing symptoms earlier during perimenopause, while others may notice those later. It is essential to employ different coping strategies, such as building strong social support networks, to improve the wellness of women across such crucial phases of their lives.
CBMJ 2025 January: Vol. 14 No. 01 P: 54-60
Relationship between Life Events and the Onset of Psychiatric Disorders in Childhood and Adolescence
Authors: Pathan Mohammad Asraful Siddike , Ullah Mohammad Shahid , Hossain Md Jahangir , Kamruzzaman Md , Rahman Wasima 
Published: February 2025

The prevalence of psychiatric problems among children and adolescents is rising in Bangladesh. Children with acute and chronic pediatric diseases have a higher likelihood of developing psychiatric problems, as their physical health challenges can lead to emotional and psychological stress, affecting their overall well-being. Our study aims to explore the relationship between life events and the onset of psychiatric disorders in children and adolescents. This observational study was conducted in the Department of Psychiatry of Community Based Medical College, Bangladesh (CBMC,B) Hospital, Mymensingh, Bangladesh, between January 2022 and February 2023. A total of 110 patients of both sexes were included in the study. The mean age of patients was 10±3.32 years. Among them, 60% were found to have emotional disorders and the life events and psychiatric disorders show that a majority life events of parent financial crisis with higher rates of (22.73%) emotional disorders. Our study indicates the relation between life events and psychiatric conditions among the paediatric population.
CBMJ 2025 January: Vol. 14 No. 01 P: 70-75
Outcome of Management of Central Serous Chorioretinopathy
Authors: Ahmed Tanvir , Begum Anjuman Ara , Kadir Syeed Mehbub Ul , Rain Md Zinnu , Chowdhury ANM Ahsanul Huda , Gupta Rishav 
Published: February 2025

This case series study on central serous chorioretinopathy (CSCR) was conducted, from April 2022 to October 2022, to assess the efficacy of laser photocoagulation and AntiVEGF in central serous chorioretinopathy. This study included all patients presented with CSCR in Bangladesh Eye Hospital, Uttara, Dhaka, a tertiary specialized private eye hospital in Bangladesh. These cases were diagnosed clinically and confirmed by fundus fluorescence angiogram and optical coherence tomography. The main features evaluated were corrected visual acuity, associated findings and complications after laser or AntiVEGF injection, if any. Other data included were age, gender, laterality of eyes, risk factors, and types of leaking. Twenty-eight cases were selected after thorough evaluation; focal laser was performed in 16 indicated cases, and intravitreal AntiVEGF (Bevacizumab) were given 4 cases of subfoveal leak central serous chorioretinopathy after 4-month observation. Post-intervention follow-up schedules were one week, one month and three months. Out of 28 cases, 7 were central serous chorioretinopathy with a sub-foveal leak in the angiogram. Among those, 10 cases were presented with central serous chorioretinopathy with pigment epithelial detachment. After three months of follow-up, subretinal fluid disappeared in 14 cases out of 16 cases of laser. Spontaneous resolution occurred in 7 cases. One patient was presented with RPE tracking. Age limits were extended from 22 to 48 years, and most were in the third decade. Central serous chorioretinopathy is most commonly present without any specific cause. Due to professional demand, most causes need intervention, which will result in fruitful visual acuity improvement with reduced subjective contrast.
CBMJ 2025 January: Vol. 14 No. 01 P:76-80
Prevalence of Polycystic Ovarian Syndrome in Women of Reproductive Age in Mymensingh Region of Bangladesh – A Sonographic Evaluation
Authors: Sharma Netay Kumer , Zahan Akter , Islam Mahzabeen , Bhowmik Kingkon Rani , Muktadira  
Published: February 2025

Polycystic ovarian syndrome (PCOS) is a common hormonal disorder affecting 5-15% of women of reproductive age. This cross-sectional study aims to provide a comprehensive understanding of the prevalence of PCOS in women of reproductive age leveraging sonographic evaluation. The study was conducted in the Department of Radiology & Imaging at Community-Based Medical College, Bangladesh (CBMC,B) Hospital, Mymensingh, Bangladesh, between January and December of 2022. Inclusion criteria were women aged between 15 and 45 years with suspected signs and symptoms of PCOS. Those with menstrual irregularities, hirsutism, severe acne, or abnormal hormone levels were excluded. Finally, a total of 120 women were included in the study. Pelvic ultrasounds were performed using a Samsung Sonoace X7 machine with a 3.5 MHz transabdominal transducer. 15(12.5%) were diagnosed with PCOS, while 105(87.5%) were negative. The age distribution shows the most significant group is 21-25 years (46.67%), followed by 15-20 years (24.17%). BMI data reveals the majority are overweight (40.83%), with an average BMI of 31.67%, and fewer in underweight (11.67%), obese (14.17%), and morbidly obese categories (1.67%). Clinical presentations include primary infertility (24.17%), secondary infertility (20.83%), chronic anovulation (15.00%), and no cases of hirsutism. Follicular diameters and ovarian volume were measured using Sono-AVC and VOCAL (3D) methods, with two identified cystic patterns: peripheral and general. Based on sonographic evaluation, our study revealed 12.5% prevalence of PCOS, with higher prevalence in the 21-25 age groups in women of reproductive age in Mymensingh region of Bangladesh.
CBMJ 2025 January: Vol. 14 No. 01 P: 89-95
Recurrent Urinary Tract Infection in Pregnancy Clinical Presentation and Feto-Maternal Outcome
Authors: Hasi Husne Har , Arefin Mohammad Shakib Uz Zaman , Rashid Harun Ur , Naher Sharfin 
Published: February 2025

There is a gap in substantial evidence regarding the increased likelihood of adverse outcomes associated with frequency of urinary tract infections (UTI) in pregnancy in our country. A cross-sectional study was conducted in the Department of Obstetrics & Gynaecology, BGB Hospital, Satkania, Chattogram, Bangladesh, from February 2023 to January 2024, to observe the maternal and fetal outcomes between respondents with single and recurrent episode of UTIs during their pregnancies. A total of 100 randomly selected women aged between 18 and 38 years having UTI during their pregnancy were enrolled in this study. Recurrent episode of UTI was observed in 38% cases. Urban women were more prevalent with the recurrence. Gestational diabetes (GDM), anaemia, cystitis were more commonly observed in recurrent UTI group. Higher proportions of preterm labor, preterm birth, low birth weight (LBW), neonatal sepsis, prematurity, intrauterine growth restriction (IUGR), and neonatal intensive care unit (NICU) admissions were evident more in recurrent UTI group compared to single episode of UTI group. Recurrence of UTI in pregnancy requires further evaluation for its risk factors during antenatal visits.
CBMJ 2025 January: Vol. 14 No. 01 P: 101-107
Comparative Efficacy of Dexmedetomidine and Fentanyl for Extubation in Post-Neurosurgical Intensive Care Unit
Authors: Bhowmick Lipon Kanti , Mahabubuzzaman Mohammad , Matin Mastura Binte , Rahim Md Abdur , Babu Md Ishaq 
Published: February 2025

The process of extubation in post-neurosurgical patients in the intensive care unit (ICU) requires careful management to ensure patient safety and comfort. Dexmedetomidine and fentanyl are two commonly used medications for sedation and analgesia during extubation. This prospective, randomized, single blind trial was conducted in the Department of Anaesthesiology, Community Based Medical College, Mymensingh, Bangladesh, between January and December of 2023, to compare the efficacy and safety of dexmedetomidine and fentanyl in post-neurosurgical ICU. The study was carried out among 50 post-neurosurgical patients requiring extubation after elective ventilation in neurosurgical ICU in a tertiary care hospital in Bangladesh. A total of 50 patients were included in this study. Inclusion criteria involved patients aged between 18 and 40 years, fairly classified as ASA (American Society of Anesthesiologists) physical status I or II, and undergone elective mechanical ventilation for less than 24 hours following any neurosurgical procedure. However, we excluded patients if they had unstable hemodynamic conditions, a Glasgow Coma Score (GCS) of <10 on the day of extubation, no swallowing attempts or visual pursuit, no cough or negative gag reflex, or if they did not meet the weaning criteria for mechanical ventilation. Patients were randomized and before extubation group-I received dexmedetomidine 0.1μg/kg, while group-II received fentanyl 1μg/kg. The degree of sedation, coughing after extubation and haemodynamic parameters were assessed and compared between the groups at the time of extubation. This study observed that single dose of 0.1μg/kg dexmedetomidine given before extubation provides better and smooth extubation as compared to fentanyl (1μg/kg).
CBMJ 2025 January: Vol. 14 No. 01 P: 108-114
Study of Glycated Hemoglobin and Lipid Profile in Normotensive Type 2 Diabetic Patients
Authors: Paul Arup Ratan , Shahidullah ASM , Tumpa Manisha Paul , Saha Kamana Rani , Farzana Shahnur , Suny Nayem Sultana , Biswas Suttam Kumar 
Published: February 2025

A cross-sectional study was conducted in the outpatient departments (OPD) of Community Based Medical College, Bangladesh (CBMC,B) Hospital, Mymensingh, Bangladesh, between January and June of 2022, to evaluate the diagnostic value of glycated hemoglobin (HbA1c) in predicting diabetic dyslipidemia. A total of 206 normotensive type 2 Diabetes Mellitus patients were selected for the study (141 females and 65 males) and the data were collected through interview in our hospital. Patients’ blood samples were sent for biochemical tests: HbA1c, fasting blood glucose (FBG) and lipid profile. Dyslipidemia was defined according to the National Cholesterol Education Programme (NCEP) Adult Treatment Panel (ATP) III guidelines. The mean age of male and female patients was 64.66±10.99 and 58.53±14.19 years respectively (p<0.001), while BMI was observed 29.08±4.58 and 31.59±6.56 kg/m2 respectively (p<0.05). The mean values of HbA1c and FBG were found slightly higher in females (p>0.05). In lipid profile, the mean values of total cholesterol (TC) and low-density lipoprotein-cholesterol (LDL-C) were significantly higher in females (p<0.05). Besides, the mean levels of triglycerides (TG) were observed slightly lower and high-density lipoprotein-cholesterol (HDL-C) slightly higher in females (p>0.05). HbA1c demonstrated significant correlations with FBG, TC, TG, LDL-C, LDL-C/HDL-C ratio and risk ratio i.e., TC/HDL-C, as compared to the patients with HbA1c value ≤7.0%, as patients with HbA1c value>7.0% had significantly higher values compared to the patients with HbAlc≤7.0% (p<0.05). However, we found no difference in values of HDL-C between two groups (p>0.05). HbA1c can be utilized as a potential biomarker for anticipating dyslipidemia in type 2 diabetic patients in addition to ensuring glycemic control.
CBMJ 2025 January: Vol. 14 No. 01 P: 122-127
Lupus Vulgaris in Gluteal Region: A Rare Presentation in a Female Patient
Authors: Sarker Susthir , Jahan Shahanaz , Paul Anindita , Islam Nahida , Nila Sadia Rubana 
Published: February 2025

Lupus vulgaris is the most common type of cutaneous tuberculosis in adults with most varied manifestation. A characteristic feature of lupus vulgaris is its extremely chronic course with slow but steady growth of the lesions over a period of many years, even decades. Head and neck are the sites commonly affected in European countries. However, in Indian subcontinent, the buttocks, thighs, and legs are the common sites of involvement. A 36-year-old woman presented with large single plaque of 5 weeks duration over left buttock. The lesion was asymptomatic except for mild pain. Histopathologic examination revealed well defined epithelioid granulomas, some multinucleated giant cells including Langhans type of giant cells. Mantoux test was strongly positive with well-defined induration. This case is being reported because of its rarity and acute presentation.
CBMJ 2025 January: Vol. 14 No. 01 P: 156-159