bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERAN DAN KEBERADAAN ENZIM METALLOTHIONEIN SEBAGAI PENGIKAT LOGAM BERAT Pb PADA PANGKAL DAN UJUNG RUMPUT LAUT GRACILARIA sp.
Authors: Tega Yatris Rambu , Herawati Endang Yuli , Kilawati Yuni 
Published: November 2023

Produksi limbah Industri dan juga buangan limbah rumah tangga yang semakin meningkat dan terjadi terus-menerus, menjadikan sungai tempat pembuangan terakhir sehingga dapat mencemari biota yang berada disekitaran sungai tersebut. Masyarakat di Desa Kupang memanfaatkan aliran sungai tersebut sebagai sumber air untuk budidaya rumput laut Gracilaria sp. Salah satu untuk mengetahui cemaran logam berat pada perairan tersebut dengan mengecek keberadaan kadar Metallothionein pada rumput laut, karena sifat Metallothionein adalah protein yang dapat mengikat logam esensial maupun non esensial. Penelitian ini bertujuan untuk mengetahui kadar Metallothionein pada Gracilaria sp. yang terekspresi pada bagian pangkal dan ujung rumput laut Gracilaria sp. Metode yang digunakan adalah metode deskriptif. Analisis pengujian kadar Metallothionein menggunakan Eliza rider. Hasil penelitian ini bahwa kondisi perairan budidaya tambak Gracilaria sp. untuk parameter suhu, pH, DO sesuai dengan kondisi perairan tambak, tetapi pada parameter salinitas tidak sesuai yaitu melebihi SNI 40 ppt, karena penguapan yang tinggi pada saat musim kemarau, sehingga kadar garamnya tinggi. Kualitas perairan sangat berpengaruh dengan keberadaan Enzim Metallothionein pada pangkal dan ujung rumput laut, Kadar enzim Metallothionein tertinggi terdapat pada bagian ujung Gracilaria sp. yaitu berkisar antara 2.026-2.734 mg/mL. Terjadinya penyerapan yang tinggi karena pada bagian ujung terdapat banyak percabangan kecil dan masih muda sehingga proses penyerapannya masih kuat, sedangkan pada bagian pangkal terdiri dari sel-sel yang sudah tua dengan percabangan yang sedikit dan jumlahnya juga sedikit.
KARAKTERISTIK DAN UJI ORGANOLEPTIK BAKSO IKAN GABUS (Channa striata) DENGAN PENAMBAHAN TEPUNG PORANG (Amorphophallus oncophyllus)
Authors: Arlin Wijayanti  , Emilyasari Desy , Rahmawati Suci H. , Qulubi M. Hadziq 
Published: November 2023

Ikan gabus (Channa striata) merupakan salah satu jenis ikan yang dimanfaatkan dalam bidang kesehatan (medicinal freshwater fish). Sebagian masyarakat tidak menyukai ikan gabus karena bentuknya yang mirip seperti kepala ular sehingga perlu dilakukan pengolahan lebih lanjut agar dapat dinikmati masyarakat luas. Salah pengolahannya melalui pembuatan bakso ikan. Penambahan tepung porang (Amorphophallus oncophyllus) dilakukan sebagai bahan alami untuk mengurangi penggunaan bahan pengenyal yang berasal dari bahan kimia sehingga lebih aman dan berasal dari bahan non kimia. Tujuan penelitian ini adalah untuk mengetahui karakteristik bakso ikan gabus dengan penambahan tepung porang (Amorphophallus oncophyllus) berdasarkan nilai kadar air, rendemen, daya ikat air, tingkat kesukaan, dan hasil uji organoleptik. Rancangan percobaan yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 4 ulangan tepung porang 0% (T0), 1% (T2), 1,5 persen (T3), 2% (T4), dan 2,5 % (T5). ). Menurut temuan penelitian ini, penambahan tepung porang dapat menghasilkan bakso ikan gabus dengan rendemen, kadar air, dan daya ikat air (WHC) yang tinggi, serta tekstur yang kenyal. Panelis dapat menerima dan sangat mengapresiasi bakso ikan gabus dengan tambahan tepung porang sebagai pengenyal alami.
Tratamentos atuais na gestão da dor crônica: uma abordagem abrangente
Authors: Alves Guimarães Maryane Karollyne , Da Silva Amaro Natália , Mendes de Souza Fontes Gomes Caroline , do Val Gonzaga Priscila , Almeida Ramos Jaegge Nicole 
Published: November 2023

A gestão eficaz da dor crônica representa um desafio significativo no campo da saúde, exigindo uma abordagem abrangente que leve em consideração diversas modalidades de tratamento. Os tratamentos atuais disponíveis para a gestão da dor crônica, destacando a importância de uma abordagem holística que integre intervenções farmacológicas e não farmacológicas são de suma importância no acompanhamento do paciente com essa patologia. Com base em uma revisão abrangente da literatura atualizada, são abordadas terapias farmacológicas como analgésicos, anti-inflamatórios e agentes adjuvantes, enquanto também se discutem terapias não farmacológicas, incluindo fisioterapia, acupuntura, terapia cognitivo-comportamental e intervenções psicossociais.
A análise crítica dos tratamentos atuais revela a necessidade de uma abordagem personalizada na gestão da dor crônica, reconhecendo a variabilidade na resposta do paciente a diferentes modalidades terapêuticas. Além disso, é explorado o papel crescente das intervenções multidisciplinares, enfatizando a colaboração entre profissionais de saúde, como médicos, fisioterapeutas, psicólogos e terapeutas ocupacionais. Esta abordagem colaborativa visa proporcionar aos pacientes uma gama diversificada de opções terapêuticas, atendendo às complexidades individuais da dor crônica
Por fim, a presente pesquisa destaca as implicações futuras e as áreas promissoras de pesquisa na gestão da dor crônica, incluindo o desenvolvimento de terapias inovadoras, avanços em medicina regenerativa e a crescente compreensão das bases neurobiológicas da dor. Ao fornecer uma visão abrangente dos tratamentos atuais e perspectivas futuras, este artigo busca contribuir para a melhoria contínua na qualidade de vida dos pacientes que enfrentam desafios associados à dor crônica.
Acceleration and Spectral Redistribution of Cosmic Rays in Radio-jet Shear Flows
Authors: Webb G. M. , Xu Y. , Biermann P. L. , Al-Nussirat S. , Mostafavi P. , Li G. , Barghouty A. F. , Zank G. P. 
Published: November 2023

Abstract
A steady-state, semi-analytical model of energetic particle acceleration in radio-jet shear flows due to cosmic-ray viscosity obtained by Webb et al. is generalized to take into account more general cosmic-ray boundary spectra. This involves solving a mixed Dirichlet–Von Neumann boundary value problem at the edge of the jet. The energetic particle distribution function f
0(r, p) at cylindrical radius r from the jet axis (assumed to lie along the z-axis) is given by convolving the particle momentum spectrum

f

0

(
∞
,
p
′
)

with the Green’s function

G
(
r
,
p
;
p
′
)

, which describes the monoenergetic spectrum solution in which

f

0

→
δ
(
p
−
p
′
)

as r → ∞ . Previous work by Webb et al. studied only the Green’s function solution for

G
(
r
,
p
;
p
′
)

. In this paper, we explore for the first time, solutions for more general and realistic forms for

f

0

(
∞
,
p
′
)

. The flow velocity
u
= u(r)
e

z
is along the axis of the jet (the z-axis).
u
is independent of z, and u(r) is a monotonic decreasing function of r. The scattering time

τ

(
r
,
p
)
=

τ

0

(
p

/

p

0

)

α

in the shear flow region 0 < r < r
2, and

τ

(
r
,
p
)
=

τ

0

(
p

/

p

0

)

α

(
r

/

r

2

)

s

, where s > 0 in the region r > r
2 is outside the jet. Other original aspects of the analysis are (i) the use of cosmic ray flow lines in (r, p) space to clarify the particle spatial transport and momentum changes and (ii) the determination of the probability distribution

ψ

p

(
r
,
p
;
p
′
)

that particles observed at (r, p) originated from r → ∞ with momentum

p
′

. The acceleration of ultrahigh-energy cosmic rays in active galactic nuclei jet sources is discussed. Leaky box models for electron acceleration are described.
Inferring the Magnetic Field from the Rayleigh–Taylor Instability
Authors: Gréa Benoît-Joseph , Briard Antoine 
Published: November 2023

Abstract
By extending the potential approach of Layzer and Goncharov to the magnetohydrodynamics equations, we find the nonlinear solutions to the single-mode Rayleigh–Taylor instability subjected to uniform magnetic fields at various inclinations. This allows us to derive the analytical prediction of the terminal bubble and spike velocities at arbitrary Atwood numbers, which are assessed against various 2D and 3D direct numerical simulations. Contrary to the linear phase, where the magnetic field inhibits or delays the instability, the growth rate may be enhanced in the nonlinear regime, exhibiting velocities faster than the Alfvén speed. This sheds light on the importance of the nondimensional number expressing the competition between the magnetic and buoyancy effects. Conversely, we show how the orientation and the intensity of the magnetic field can be simply inferred from these solutions.
L’économie sociale et solidaire
Authors: Demurger Pascal , Saddier Jérôme , Cazeneuve Nathan 
Published: November 2023

Comment démocratiser les entreprises ? Historiquement, les entreprises mutualistes ont constitué une alternative à la propriété et à la gestion privée du capital. De quelles dynamiques de transformation du capitalisme sont-elles aujourd’hui porteuses ? Pascal Demurger, directeur général de la Maif, et Jérôme Saddier, président du Crédit Coopératif et d’ESS France, éclairent ici les évolutions et les ambitions contemporaines de l’économie sociale et solidaire et leur portée pour l’ensemble de l’économie.
Les femmes du lien
Authors: Jarousseau Vincent , Duval-Cos Tristan 
Published: November 2023

Photographe, Vincent Jarousseau, a suivi pendant plusieurs mois le quotidien de travailleuses des professions du soin. Il revient ici sur l’expérience de travail, les difficultés et la politisation de ces « femmes du lien ».
Les puffs, révélateurs de l’indécision gouvernementale
Authors: Basset Bernard , Daimé Patrick 
Published: November 2023

Alors que l’intérêt de la cigarette électronique fait l’objet de débats scientifiques, l’arrivée sur le marché d’un produit marketing, les puffs, destiné aux adolescents est un nouveau défi pour les autorités sanitaires. Comment prévenir l’entrée des jeunes dans la dépendance à la nicotine, sans interdire le recours au vapotage par les fumeurs qui souhaitent arrêter la cigarette ?
Éradiquer sans prohiber ? Évolutions internationales des politiques publiques de contrôle du tabac au xxi e siècle
Authors: Taiclet Anne-France 
Published: November 2023

Cet article propose une synthèse analytique des tendances ­internationales observables dans les politiques publiques de régulation du tabac dans ce premier quart du xxi	e siècle. Il revient d’abord sur la densification du répertoire d’actions publiques et l’affirmation d’une stratégie consistant à encercler le tabac (désigné comme un ennemi) et à l’attaquer par le biais de différentes tactiques matérielles et symboliques. La régulation du tabac est un processus en mouvement permanent, du fait de l’intensité des échanges de coups entre protagonistes : ces interactions agonistiques se traduisent dans des luttes de cadrage qui entraînent une diversification des qualifications du tabac, comme problème sanitaire mais aussi environnemental et social. Enfin, l’article montre comment, à l’issue de ce quart de siècle de mobilisations diverses, s’esquisse la formulation progressive d’un changement de paradigme, où l’objectif de l’action publique ne serait plus seulement le contrôle du tabac mais sa disparition comme bien courant.
Effects of clove essential oil on eggshell bacterial load, antibacterial sensitivity, and hatchability
Authors: Hassan Abdallah S. I. , Morsy Eman A. , El. Moustafa Kout-Elkloub M. , Ibrahim Faten A. , Elmenawey Mohamed A. 
Published: November 2023

Background and objective
Clove essential oil’s (CEO) physical and chemical properties allow for its potent antibacterial action. This study sought to determine the impact of various CEO disinfectant concentrations on the eggshell bacterial load, embryonic mortality, hatchability, and chick quality.

Materials and methods
A total of 1500 fertile chicken eggs were randomly divided into five treatment groups. Group one was sprayed with a commercial disinfectant (BioSentry 904), the second group was sprayed with ethyl alcohol 70%, and the last three groups were sprayed with 0.5, 1, or 2% of CEO. After spraying, eggs in each group were used for the determination of total bacterial load on the eggshell, hatchability, embryonic mortality, and chick quality.

Results and conclusion
Results showed that the bacterial load on the eggshell declined with the increase in the concentration of CEO. The use of CEO at 1, 2%, or BioSentry 904 resulted in the lowest bacterial load. However, hatchability of set and fertile eggs for the group treated with CEO at 0.5% was numerically greater than other groups, while chick quality grade (A) was numerically greater by CEO at 1% concentration. The chick yield of the egg group treated with CEO at 1% was significantly higher than in the control group. Embryonic mortalities for all groups were statistically similar. In conclusion, using CEO at different concentrations 1, 2%, or BioSentry 904 in disinfecting broiler breeder eggs can effectively reduce the bacterial load on eggshells. In addition, using CEO improved chick quality and chick yield without any adverse effect on hatchability. Consequently, it is considered a strong competitor to BioSentry 904 and a less hazardous disinfectant for hatching egg disinfection on a commercial scale.
A Study on Assessment and Correlations between Eating Attitudes, Body Image Perception and Self-esteem in Medical Students of Mumbai
Authors: Shah Priyanshi Vikas , Somaiya Mansi P. , Subramanyam Alka Anand 
Published: November 2023

Introduction:
Adolescents and young adults place significant value to appearance. Medical students are likely to be vulnerable to dissatisfaction with appearance and maladaptive eating attitudes.

Aims and Objectives:
This study was designed to study the eating attitudes, body image perception, and self-esteem in MBBS students and their correlations with each other and with body mass index (BMI), to identify students at risk and possibly plan measures for intervention.

Methodology:
A study was conducted on 700 medical students (including interns), with electronic questionnaires assessing sociodemographic data, eating attitudes, body image perception, and self-esteem. Using the Chi-square tests and t-tests, the parameters were studied and correlations using Spearman’s rank correlation were established.

Results:
Students with a higher BMI were at a greater risk of eating disorder (ED), higher concerns with body perception, and lowered self-esteem. Those with a higher risk of ED were associated with body dissatisfaction and lower self-esteem. Body image distortions were associated with low self-esteem.

Conclusions:
ED risk is associated with body dissatisfaction and lower self-esteem in medical students. Future studies are required to establish this relation.
Translucency characteristics of permanent maxillary central incisor in Indian population: An analytical cross-sectional study
Authors: Mishra Siddharth , Murthy Pranav , Ahuja Dhruv , Thomas Manuel S. , Natarajan Srikant , Pai Umesh 
Published: November 2023

Abstract

Background:
Understanding the optical characteristics, especially the translucency patterns (TPs) in teeth can assist clinicians in creating biomimetic restorations.

Aim:
This study assessed the differences in enamel TPs and the area of translucency (AOT) in the most dominant teeth of an individual’s smile according to their age and gender.

Materials and Methods:
This cross-sectional study was conducted on 140 consented individuals. Based on the age, there were four groups with 35 subjects in each. The digital imaging method is used to classify and differentiate different TPs. The AOT was measured with the assistance of ImageJ 1.51j8 software.

Statistical Analysis Used:
One-way ANOVA with a post hoc test was used to test the statistical significance difference among the various age groups, and an independent t-test was used to test the variations between genders.

Results:
The outcome of this study showed that the AOT was the highest for the 50 and above age group as compared to other age groups (P = 0.003). Although there were variations in the TPs between the two genders, the AOT showed no significant difference.

Conclusion:
The area of incisal third translucency in the upper central incisors varied between different age groups. However, gender had no influence in the area of incisal translucency. Wide variations in the TPs were seen based on age and gender.
The prevalence of COVID-19 infection among gynecologic oncology patients receiving cancer treatment in a COVID-19 referral hospital
Authors: Medalla Renee Riza Cartago , Luna Jericho Thaddeus P. 
Published: November 2023

INTRODUCTION:
Cancer patients are more susceptible to coronavirus disease-19 (COVID-19) infection because they are immunosuppressed by their disease or therapy, most of them have coexisting medical conditions, and they frequently visit hospitals for treatment and surveillance.

OBJECTIVE:
The objective of this study was to determine the prevalence of COVID-19 infection among gynecologic oncology patients receiving treatment in a COVID-19 referral hospital.

MATERIALS AND METHODS:
A descriptive, cross-sectional study involving 47 gynecologic cancer patients receiving treatment from June 2020 to December 2020 was performed. All patients underwent SARS-CoV-2 reverse transcription-polymerase chain reaction (RT-PCR) swab test and symptom and exposure assessment before the start of cancer treatment. Patients with negative SARS-CoV-2 RT-PCR swab test results received their planned treatment, and a repeat swab test and triage assessment were done midtreatment and after treatment.

RESULTS:
Five (10.6%) patients had positive baseline SARS-CoV-2 RT-PCR swab results, but all proceeded with treatment after negative results were obtained. Only 1 (2.13%) patient had a positive SARS-CoV-2 RT-PCR swab test result at midtreatment. All patients had no COVID-19-associated symptoms and none of them tested positive for COVID-19 infection posttreatment.

CONCLUSION:
The prevalence of COVID-19 infection among gynecologic cancer patients receiving cancer treatment is 2.13%. All patients who had positive SARS-CoV-2 RT-PCR swab test results at baseline or midtreatment were able to continue and complete treatment. There were no severe clinical events or mortalities among those affected with COVID-19 infection.
Cardiovascular implications of inflammatory bowel disease: An updated review
Authors: Bhardwaj Arshia , Singh Arshdeep , Midha Vandana , Sood Ajit , Wander Gurpreet Singh , Mohan Bishav , Batta Akash 
Published: November 2023

Emerging data highlights the heightened risk of atherosclerotic cardiovascular diseases (ASCVD) in patients with chronic inflammatory disorders, particularly those afflicted with inflammatory bowel disease (IBD). This review delves into the epidemiological connections between IBD and ASCVD, elucidating potential underlying mechanisms. Furthermore, it discusses the impact of current IBD treatments on cardiovascular risk. Additionally, the cardiovascular adverse effects of novel small molecule drugs used in moderate-to-severe IBD are investigated, drawing parallels with observations in patients with rheumatoid arthritis. This article aims to comprehensively evaluate the existing evidence supporting these associations.
To achieve this, we conducted a meticulous search of PubMed, spanning from inception to August 2023, using a carefully selected set of keywords. The search encompassed topics related to IBD, such as Crohn’s disease and ulcerative colitis, as well as ASCVD, including coronary artery disease, cardiovascular disease, atrial fibrillation, heart failure, conduction abnormalities, heart blocks, and premature coronary artery disease. This review encompasses various types of literature, including retrospective and prospective cohort studies, clinical trials, meta-analyses, and relevant guidelines, with the objective of providing a comprehensive overview of this critical intersection of inflammatory bowel disease and cardiovascular health.
Hypertrophic cardiomyopathy secondary to deficiency in lysosome-associated membrane protein-2: A case report
Authors: Zhao Ye-Tong , Cao Xiu-Qun , Mu Xiao-Lin 
Published: November 2023

BACKGROUND
Danon disease (DD), in which mutations in the X-linked lysosome-associated membrane protein-2 (LAMP-2) gene result in hypertrophic cardiomyopathy, is a rare disease, reported primarily in small samples or cases. However, with the development of cardiac magnetic resonance imaging and genetic technology in recent years, the number of reports has increased.
CASE SUMMARY
We report a case of DD in an adolescent male patient, confirmed by genetic testing. The patient was admitted to our hospital with complaints of a three-year history of chest tightness and shortness of breath. His preliminary clinical diagnosis is hypertrophic cardiomyopathy. Our report includes the patient’s clinical course from hospital admission to death, step-by-step diagnosis, treatment course, and noninvasive imaging features. We highlight how a noninvasive diagnostic approach, based solely on clinical and imaging “red flags” for DD, can be used to achieve a diagnosis of DD with a high degree of confidence.
CONCLUSION
DD is a very dangerous cardiomyopathy, and it is necessary to achieve early diagnosis and treatment.
Down syndrome child with multiple heart diseases: A case report
Authors: Kong Mo-Wei , Li Yi-Jing , Li Jun , Pei Zhen-Ying , Xie Yu-Yu , He Guo-Xiang 
Published: November 2023

BACKGROUND
Down syndrome, also known as trisomy 21 syndrome, is commonly associated with congenital heart disease, and can often result in early formation of pulmonary hypertension. The development of pulmonary hypertension can result from factors such as intracardiac and macrovascular shunts, and upper airway obstruction or hypoplasia of lung tissue. Individuals with Down syndrome and congenital heart disease have a significantly lower average life expectancy, with surgical intervention being the most viable treatment option to improve longevity.
CASE SUMMARY
We report the case of a 13-year-old boy with Down syndrome presenting with atrial septal defect and patent ductus arteriosus along with severe pulmonary hypertension. The electrocardiogram shows sinus rhythm and right ventricular hypertrophy. The echocardiogram shows an atrial septal defect with interrupted echo in the interatrial septum, measuring 0.813 cm in length. The patient was initially refused to be offered surgical treatment by many hospitals due to the high surgical risk and pulmonary artery resistance. After discussing the patient’s diagnosis and treatment options, we ultimately recommended surgical treatment. However, the patient and their family declined this recommendation and chose to be discharged. During the follow-up period of 6 mo, there were no significant improvements or deteriorations in the patient’s condition.
CONCLUSION
In conclusion, this case highlights the challenges faced by individuals with Down syndrome and congenital heart disease complicated by severe pulmonary hypertension. Timely intervention and a multidisciplinary approach are crucial for improving prognosis and life expectancy. Further research is needed to enhance our understanding and develop effective interventions for this population.
Astrobiologia no ensino médio
Authors: Chefer Claudiane , Oliveira André Luis de 
Published: November 2023

Buscou-se por meio de uma pesquisa qualitativa de cunho documental, identificar na Base Nacional Comum Curricular e no Referencial Curricular para o Ensino Médio do Paraná-PR, componente curricular Biologia, habilidades, temáticas e conteúdos que podem ser associados a ciência Astrobiologia. Foi possível por meio da análise, inferir que tanto no currículo proposto pela base, quanto nos referenciais paranaenses, são postos vários conteúdos que, a partir de um olhar abrangente e contextualizado, contemplam os conceitos e conhecimentos científicos que embasam a pesquisa astrobiológica. Inclusive nas orientações paranaenses, a Astrobiologia é comtemplada como conteúdo escolar. Partindo deste contexto, a identificação de conceitos e relações diretas representam marcos conceituais da inserção da Astrobiologia no currículo brasileiro e paranaense para o EM.