bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trebizond Expeditions of F.I. Uspensky: a Brief Overview of Research
Authors: Цыпкина А.Г. 
Published: December 2023

Статья представляет собой краткий обзор исследований Трапезундских экспедиций Ф.И. Успенского 1916 и 1917 гг. с результатами описания рукописей и проведения археологических раскопок. Характеризуются особенности и трудности работы, а также организации экспедиции в прифронтовой полосе периода Первой мировой войны. В статье рассказано об основных задачах, которые ставили перед собой русские учёные, и результатах. Показывается роль экспедиций Ф.И. Успенского в исследовании Трапезунда и перечисляется потерянный экспедицией материал.
The article represents a brief overview of the Trebizond expeditions research carried out by the lead of Russian historian and byzantinist F.I. Uspensky in 1916 and 1917. The results of descriptions of manuscripts and archaeological excavations are listed. The difficulties of the work, as well as the organization of the expedition in the front line during the First World War, are characterized. The article describes the main tasks that Russian scholars set for themselves, their falls and success. The role of F.I. Uspensky’s expeditions in the context of Trebizond research is shown. The lists of the material lost by the expedition is presented.
“Science was his passion”: emotive code of memories about English botanist Joseph Banks (1743–1820)
Authors: Шипицына Ю.С. 
Published: December 2023

Английский ботаник Джозеф Бэнкс (1743–1820), по воспоминаниям современников и потомков, выделялся своим темпераментом на фоне других ученых. Оригинальные паттерны поведения позволили добиться признания и достичь вершины академической карьеры в Британии – занять пост президента Лондонского королевского общества. Статья представляет результаты исследования комплекса некрологов и воспоминаний, опубликованных в столетнюю годовщину смерти Бэнкса. Анализ текстов на предмет эмотивных категорий, описывающих характер Бэнкса, показывает, что особое внимание авторы обращают на энтузиазм ученого. Страстная увлеченность, душевный подъем, азарт, любовь и другие субъективные переживания, свойственные Бэнксу, встречают одобрение, а сам он становится примером для подражания. Случай Бэнкса показывает, что подобные проявления субъективности, порицаемые еще в XVII – начале XVIII века, в более позднее время становятся важнейшей составляющей образа ученого. Неординарная личность Бэнкса оказала влияние на формирование образа ученого в английской науке XIX века.
English botanist Joseph Banks, according to contemporaries’ and successions’ memoirs, had been distinguished by his temperament among other scientists. Original patterns led him gain recognition and pinnacle of academic career in Britain – the position of president of the Royal Society of London. The article submits the results of research of obituaries and memories, published in the 100-years death anniversary of J. Banks. The analysis of texts’ emotive categories, describing Banks’s character, shows that the special attention was paid to enthusiasm of scientist. Passion, inspiration, ardor, love and other subjective feelings, typical for Banks, met with approval and Banks became a role model in the end of 18th – beginning of 20th c. The case of Banks suggests such manifestation of subjectivity, blamed in the 17th -18thcс., in more late time emerge as one of the most important part of scientist’ image. Outstanding personality of Banks, as the author’s opinion, influenced on making an image of scientist in the English science.
«Freed from the Camp Did Not Mean Liberated from the Camp»: Artistic Creativity as a Method of Living Through Traumatic Events
Authors: Подледнов Д.Д. , Казанцева Е.Д. 
Published: December 2023

Статья посвящена взаимосвязи биографии и творчества Евфросинии Керсновской – писательницы, художницы–аутсайдера, заключенной ГУЛАГа. Согласно концепции постпамяти (М. Хирш), Е. Керсновская принадлежит к числу «первого» поколения – тех лиц, при жизни которых происходили травмирующие события истории: в данном случае, кардинальное ужесточение политического фона, а также создание системы ГУЛАГа. После освобождения Керсновская написала мемуары, сопроводив их визуальным нарративным рядом. Авторы статьи с помощью формально–стилистического и семиотических методов предприняли попытку проанализировать визуальный язык художницы и выявить особенности сюжетной линии мемуаров, раскрывающие специфику культуры ГУЛАГа. Хронологически выстроенный рассказ и авторское деление мемуаров на тетради и главы позволяет последующим поколениям («второе» и «третье» поколение после очевидцев) «пройти» путь Евфросинии Керсновской – от помещицы до заключенной ГУЛАГа. В случае Керсновской и некоторых других художников-заключенных, художественное творчество и создание мемуаров оказывало терапевтический эффект и способствовало безопасному «повторению», проживанию и преодолению индивидуальной психотравмирующей ситуации.
The article is devoted to the relationship between the biography and work of Euphrosyne Kersnovskaya who was a writer, an outsider artist, and a prisoner of the Gulag. In accordance with the concept of post-memory proposed by Marianne Hirsch, the figure of Kers-novskaya belongs to the "first" generation – the individuals and traumatic events of history and social catastrophes took place during the lifetime (a radical tightening of the political background in the USSR, as well as the creation and development of the Gulag system). After her release Kersnovskaya wrote her memoirs, accompanied by a visual narrative series. The authors, using formal-stylistic and semiotic methods, attempted to analyze the visual language of the artist, as well as to identify the key features of the storyline of the memoirs, which reveal the specifics of the GULAG culture. The chronologically structured story and the author's division of memoirs into notebooks and chapters allows subsequent generations (the "second" and "third" generation after eyewitnesses) to "pass" the path of Kersnovskaya – from a landowner to a prisoner of the Gulag. According to the case of Euphrosyne Kersnovskaya, as well as some other imprisoned artists, it can be argued that artistic creation and the creation of memoirs had a therapeutic effect and contributed to the safe “repetition”, living, and overcoming an individual psychotraumatic situation.
On the Background of the Marble Palace: Portraits of the First Soviet Cultural Historians
Authors: Сыченкова Л.А. 
Published: December 2023

В рецензии анализируется коллективная монография «Отцы-основатели РАИМК: их жизненный путь и вклад в науку» (Науч. ред.-сост. В.А. Горончаровский. СПб.: ИИМК РАН. 2022. 872 с.). Собранные в одной книге творческие портреты 48 советских историков культуры, археологов, искусствоведов, музеологов позволяют преодолеть, закрепившиеся за десятилетия в историографии наслоения легенд, вымыслов, необоснованных обвинений и преувеличенной канонизации, по-новому оценить уникальный опыт институционального центра гуманитарного знания в контексте сложного социокультурного пространства 1920–1930-х гг.
The review analyses the collective monograph "The Founding Fathers of the RAIMK: Their Life and Contribution to Science" (Editor-in-Chief. V.A. Goroncharovsky. SPb: IIMC RAS. 2022. 872 p.). The creative portraits of 48 brilliant Soviet cultural historians, archaeologists, art historians and museologists collected in one book allow us to overcome the legends, fabrications, unfounded accusations, and exaggerated canonisation which became entrenched in historiography over decades, to evaluate anew the unique experience of institutional centre of humanitarian knowledge in the context of complex socio-cultural space of 1920–1930s.
The Apology for the Forgotten Emperor
Authors: Ведешкин М.А. 
Published: December 2023

В статье представлена рецензия на монографию Я.В. Драйверса The Forgotten Reign of the Emperor Jovian (363–364): History and Fiction. Отмечается методологическая новизна подхода автора и противоречивость некоторых суждений и выводов.
This article presents a review of The Forgotten Reign of the Emperor Jovian(363–364): History and Fiction by J.W. Drijvers. It emphasizes both the methodological novelty of his approaches and the controversial nature of some of his judgments and conclusions.
Human and Animals in the High Middle Ages Culture: about "The Animal Turn of the Thirteenth Century..." by N. Harris
Authors: Грозов С.С. 
Published: December 2023

Рецензия посвящена монографии Н. Харриса, который предложил концепцию «анималистического поворота» XIII в., выразившегося в изменении взглядов на животный мир, практик изучения и взаимодействия с животными. На основе широкого круга разножанровых источников Харрис исследовал влияние трудов Аристотеля на последующую энциклопедическую традицию, роль образов животных для конструирования аристократической идентичности и подвижность границы между животным и человеком в представлениях разных групп средневекового общества.
This review discusses N. Harris's monograph, exploring the concept of the "animal turn" in the 13th c., expressed in the changing views of the animal world, practices of studying and interacting with animals. Based on a wide range of sources, the author examines the influence of Aristotle's works on subsequent encyclopaedic traditions, the role of animal imagery in constructing aristocratic identity, and the fluidity of the boundary between animal and human in the perceptions of different groups in medieval society. The critical analysis of Harris' work involves aт examination of the main propositions of the monograph by chapter, a demonstration of the strengths and fragilities of the author's concept.
Epoch-Makers in Intellectual History: Pyotr Tchaadaev and the Bengal Renaissance Thinkers
Authors: Скороходова Т.Г. 
Published: December 2023

Автор сопоставляет П.Я. Чаадаева и мыслителей Бенгальского Возрождения в свете особой роли, сыгранной ими в интеллектуальной истории их стран в контексте модернизационных трансформаций России и Индии XIX века. Их сходство определяется в терминах М. Бубера как родство «проблематичных мыслителей» и их «философий кризиса». Мыслители ощутили трансформирующийся характер своего времени, осмыслили его как кризис в социальной, культурной и моральной областях и стали основателями философии кризиса. Последняя понимается как условный комплекс вопросов и ответов, обозначающих векторы мысли и её проблемные поля. Как П. Ча-адаев, так и бенгальские интеллектуалы поднимали вопросы о духовном, моральном и социальном состоянии обществ, о подлинной сути религии, о традициях, истории, социальном устройстве и цивилизационном облике своих стран, о путях и методах возрождения народа в сложившейся ситуации. Появление философий кризиса проблематизирует сознание российского и индийского обществ и порождает эпохи. П. Чаадаев положил начало эпохе религиозной и социальной мысли, решающей фун-даментальные проблемы бытия народа и российского общества в мире. Бенгальские мыслители от Раммохана Рая до Рабиндраната Тагора, анализируя проблемы бытия Индии в мире и в истории, создали эпоху национально-культурного ренессанса.
The article compares P.Y. Tchaadaev and the thinkers of the Bengal Renaissance in the light of the role they played in the intellectual history of their countries in the context of the modernizing transformations of Nineteenth-century Russia and India. The typological similarities are defined in terms of M. Buber's "problematic thinkers" and "philosophy of crisis". The thinkers perceived the transforming nature of their time, conceived it as a social, cultural, and moral crisis, and became the founders of a philosophy of crisis. The latter is understood as a conventional complex of questions and answers denoting the vectors of thought and its problematic fields. Both Pyotr Tchaadaev and Bengal intellectuals raised questions about the spiritual, moral, and social state of society, the true essence of religion, about traditions, history, social structure and civilizational image of their countries, about the ways and methods of revival of the people in their present situation. The emergence of the philosophy of crisis problematized the consciousness of Russian and Indian societies and gave rise to epochs in intellectual history. P. Tchaadaev ushered in the epoch of religious and social thought that addressed the fundamental problems of existence of the people and Russian society in the world. Bengal thinkers from Rammohun Roy to Rabindranath Tagore, analyzing the many problems of India’s being in the world and in history, created the epoch of national-cultural renaissance.
Treatment of Metastatic Renal Cell Carcinoma with Checkpoint Inhibitors in
Clinical Practice in the Volga-Ural Region of the Eurasian Continent
Authors: Rakhimov Radmir R. , Sultanbaev Aleksandr V. , Izmailov Adel A. , Menshikov Konstantin V. , Zabelin Vadim M. , Izmailov Albert A. , Gilyazova Gulshat R. , Izmailova Svetlana M. , Bakhtiyarova Ksenia S. , Izmailova Angelina A. , Gilyazova Irina R. 
Published: December 2023

Introduction:
Renal cancer ranks 10th in the mortality structure of the Russian Federation. The introduction
of checkpoint inhibitors has changed the paradigm of treatment of patients with malignant neoplasms.

Method:
Data from clinical trials have shown good progression-free median and median overall survival.
Each cancer center has been accumulating its own experience in treating patients with renal cell cancer by applying
modern target drugs and immunotherapy.

Result:
In routine clinical practice, oncologists do not get the results that have been demonstrated in clinical
trials when evaluating the effectiveness of the therapy.

Conclusion:
In this single-center clinical study, we discuss the results of using nivolumab as mono-therapy
and the combination of nivolumab with ipilimumab in metastatic renal parenchyma cancer patients.
Flavonoids as G Protein-coupled Receptors Ligands: New Potential
Therapeutic Natural Drugs
Authors: Chda Alae , Bencheikh Rachid 
Published: December 2023

Abstract:
G protein coupled receptors (GPCRs) are among the largest family of cell surface re-ceptors found in the human genome. They govern a wide range of physiological responses in both health and diseases, making them one of the potential targeted surface receptors for pharmaceuti-cals. Flavonoids can modulate GPCRs activity by acting as allosteric ligands. They can either en-hance or reduce the GPCR's effect. Emerging research shows that individual flavonoids or mix-tures of flavonoids from plant extracts can have relevant pharmacological effects against a num-ber of diseases, particularly by influencing GPCRs. In the present review, we are considering to give a comprehensive overview of flavonoids and related compounds that exhibit GPCRs activity and to further explore which beneficial structural features. Molecular docking was used to strengthen experimental evidence and describe flavonoid-GPCRs interactions at molecular level.
Deciphering the Function of New Therapeutic Targets and Prospective Biomarkers in the Management of Psoriasis
Authors: Purewal Japneet Singh , Doshi Gaurav Mahesh 
Published: December 2023

Abstract:Psoriasis is an immune-mediated skin condition affecting people worldwide, presenting at any age, and leading to a substantial burden physically and mentally. The innate and adaptive immune systems interact intricately with the pathomechanisms that underlie disease. T cells can interact with keratinocytes, macrophages, and dendritic cells through the cytokines they secrete. According to recent research, psoriasis flare-ups can cause systemic inflammation and various other co-morbidities, including depression, psoriatic arthritis, and cardio-metabolic syndrome. Additionally, several auto-inflammatory and auto-immune illnesses may be linked to psoriasis. Although psoriasis has no proven treatment, care must strive by treating patients as soon as the disease surfaces, finding and preventing concurrent multimorbidity, recognising and reducing bodily and psychological distress, requiring behavioural modifications, and treating each patient individually. Biomarkers are traits that are assessed at any time along the clinical continuum, from the early stages of a disease through the beginning of treatment (the foundation of precision medicine) to the late stages of treatment (outcomes and endpoints). Systemic therapies that are frequently used to treat psoriasis provide a variety of outcomes. Targeted therapy selection, better patient outcomes, and more cost-effective healthcare would be made possible by biomarkers that reliably predict effectiveness and safety. This review is an attempt to understand the role of Antimicrobial peptides (AMP), Interleukin-38 (IL-38), autophagy 5 (ATG5) protein and squamous cell carcinoma antigen (SCCA) as biomarkers of psoriasis.
The Effect of Selenium, Zinc, and their Combined Supplementation
on Cardiometabolic Biomarkers-comparing their Effects in the
Energy Restriction and High-fat Diet Methods in Obese Rats
Authors: Hasani Motahareh , Monfared Vahid , Aleebrahim-Dehkordi Elahe , Jafari Ali , Agh Fahimeh , Khazdouz Maryam , Vahid Farhad , Vafa Mohammadreza 
Published: December 2023

Introduction:
The fat distribution in the body determines the risk of cardiometabolic
problems such as heart disease and diabetes. Some dietary supplements,
such as selenium and zinc, possess lipolytic and anti-angiogenic functions, which may
be a useful strategy in reducing the risk of cardiometabolic complications. This study
evaluated the effect of zinc (Zn), selenium (Se), and their combined supplementation
on cardiometabolic risk factors in male Wistar rats in two nutritional models, including
caloric restriction (CR) and high-fat diet (HFD).

Methods and Materials:
The 48 male Wistar rats were divided into three diet groups
(HFD and CR and normal diet (ND)). The HFD group was subdivided into four
groups (N=8 rats in each group) that received (HFD+Se), (HFD+Zn), (HFD+Zn+Se),
and HFD alone as the control group, respectively. After 8 weeks of intervention,
biochemical tests were performed on serum levels, including measurement of lipid
profile (triglyceride, Cholesterol, LDL and HDL) and glycemic indices (fasting blood
sugar, insulin and insulin sensitivity markers).

Results:
The results showed that supplementation significantly improved the lipid
profile (P <0.001). A comparison of glucose homeostasis indices in the study groups
also showed a significant difference. The serum level of glucose was higher in the HFD
group than in the intervention groups (P <0.001). Also, the rate of improvement of lipid
profile and glycemic indexes in the group receiving the combination of two
supplements showed a better trend than those receiving zinc and selenium alone.
However, the values were statistically significant only for glucose homeostasis indices
(P <0.001).

Conclusion:
Although obesity is a multifactorial condition, controlling other risk factors,
zinc and selenium and their combined supplementation can lead to promising solutions
for the treatment of obesity-induced glucose and lipid homeostasis disorders.
Recent Trends in Nanoparticulate Delivery System for Amygdalin as Potential Therapeutic Herbal Bioactive Agent for Cancer Treatment
Authors: Prajapati Mahendra , Deshmukh Rohitas , Harwansh Ranjit K. 
Published: December 2023

:
Cancer is the deadliest and most serious health problem. The mortality rate of cancer patients
has increased significantly worldwide in recent years. There are several treatments available,
but these treatments have many limitations, such as non-specific targeting, toxicity, bioavailability,
solubility, permeability problems, serious side effects, and a higher dose. Many people prefer phytomedicine
because it has fewer side effects. However, amygdalin is a naturally occurring phytoconstituent.
It has many harmful effects due to the cyanide group present in the chemical structure.
Many scientists and researchers have given their thoughts associated with amygdalin and its toxicities.
However, there is a need for a more advanced, effective, and newer delivery system with reduced
toxicity effects of amygdalin. Nanotechnology has become a more refined and emerging medical
approach, offering innovative research areas to treat cancer. This review focuses on the use of
amygdaline as herbal medicine encapsulating into several nanoparticulate delivery systems such as
silver nanoparticles, graphene oxide nanoparticles, gold nanoparticles, nanofibers, nanocomposites,
niosomes, and magnetic nanoparticles in the treatment of cancer. In addition, this article provides
information on amygdalin structure and physical properties, pharmacokinetics, toxicity, and challenges
with amygdalin.
Insights into the Molecular Mechanisms of Bushen Huoxue Decoction in Breast Cancer via Network Pharmacology and in vitro experiments
Authors: Liang Hongyi , Yin Guoliang , Shi Guangxi , Liu Xiaofei , Liu Zhiyong , Li Jingwei 
Published: December 2023

Aim:
Breast cancer (BC) is by far seen as the most common malignancy globally,
with 2.261 million patients newly diagnosed, accounting for 11.7% of all cancer patients, according
to the Global Cancer Statistics Report (2020). The luminal A subtype accounts for at
least half of all BC diagnoses. According to TCM theory, Bushen Huoxue Decoction (BSHXD)
is a prescription used for cancer treatment that may influence luminal A subtype breast cancer
(LASBC).

Objectives:
To analyze the clinical efficacy and underlying mechanisms of BSHXD in LASBC.

Materials and Methods:
Network pharmacology and in vitro experiments were utilized to foresee
the underlying mechanism of BSHXD for LASBC.

Results:
According to the bioinformatics analysis, BSHXD induced several proliferation and
apoptosis processes against LASBC, and the presumed targets of active components in BSHXD
were mainly enriched in the HIF-1 and PI3K/AKT pathways. Flow cytometry assay and western
blotting results revealed that the rate of apoptosis enhanced in a dose-dependent manner with
BSHXD concentration increasing, respectively. BSHXD notably downregulated the expressions
of HIF-1α, P-PI3K, PI3K, P-AKT and AKT proteins. However, adding an HIF-1α agonist restored
those protein levels.

Conclusion:
The study proved that the mechanism of BSHXD in LASBC may be connected to
suppressing proliferation by inhibiting the activity of the HIF-1α/PI3K/AKT signaling pathway
and promoting apoptosis via the Caspase cascade in LASBC cells.
Recycling the Spent Lithium-ion Battery into Nanocubes Cobalt Oxide
Supercapacitor Electrode
Authors: Bakr Zinab Hassanien , Abdelaziz Aboelazm Eslam Atef , Khe Cheng Seong , Mohammed Ali Gomaa Abdelgawad , Chong Kwok Feng 
Published: December 2023

Background::
Cobalt oxide nanocubes have garnered significant attention as potential
supercapacitor electrodes due to their unique structural and electrochemical properties. The
spent lithium-ion batteries (LiBs) are considered as zero-cost source for cobalt oxide production.

Objective::
The aim of this work is to recover cobalt oxide from spent LiBs and study its
electrochemical performance as a supercapacitor electrode material.

Method::
This study uses an electrodeposition method to obtain cobalt oxide honeycomb-like
anodes coated on Ni foam substrates from spent Li-ion batteries for supercapacitors applications.
The effect of annealing temperature on the cobalt oxide anode has been carefully investigated;
450 ºC annealing temperature results in nanocubes on the surface of the cobalt oxide electrode.
X-ray diffraction confirmed the formation of the Co3O4-NiO electrode.

Results::
The Co3O4-NiO nanocubes electrode has shown a high specific capacitance of 1400 F
g-1 at 1 A g-1 and high capacitance retention of ~96 % after 2250 cycles at a constant current
density of 10 A g-1 compared to 900 F g-1 at 1 A g-1 as for prepared Co3O4 honeycomb.

Conclusion::
This strategy proves that the paramount importance of Co3O4-NiO nanocubes, meticulously
synthesized at elevated temperatures, as a supremely effective active material upon
deposition onto transition metal foam current collectors, establishing their indispensability for
supercapacitor applications.