bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERTUMBUHAN DAN PRODUKSI JAGUNG PULUT (Zea mays ceratina) DENGAN PEMUPUKAN ANORGANIK DAN PUPUK KANDANG DIPERKAYA N-ORGANIK DAN P-ALAM
Authors: Kartikasari Ratna Dwi , Lukiwati Dwi Retno , Widjajanto Didik Wisnu 
Published: October 2023

The growth and yield of waxy corn are determined by organic and inorganic fertilizers. The addition of organic-N (N-Leucaena leucocephala) and nature-P (P-rock phosphate) can be used as a substitute for inorganic fertilizers (urea and TSP). The present study investigated the effects of N-leucaena leucocephala and P-rock phosphate enriched manure (manure plus) on the growth and yield of waxy corn. The experiment was conducted in a randomized complete block design with seven treatments and four replicates: T0 (urea + TSP), T1 (urea+TSP + cattle manure), T2 (urea+TSP + goat manure), T3 (urea+TSP + poultry manure), T4 (N-L. leucocephala+ P-rock phosphate + goat manure), T6 (N-L. leucocephala+ rock phosphate + poultryobserved were plant height, chlorophyll content, cob weight with cornhusk and without cornhusk, and cob length with cornhusk and without cornhusk. The data was analyzed using analysis of variance, followed by Duncan's multiple range tests.The results showed that manure plus had a significant effect (P<0.05) on cob weight with cornhusk and without cornhusk and cob length without cornhusk. The parameters of plant height, leaf chlorophyll content, and cob length with cornhusk were similar in all treatments. Based on the research results, it may be concluded that the addition of Leucaena leucocephala and rock phosphate to manure can improve the quality of the organic fertilizer and can replace inorganic fertilizer.
ANALISIS INDEKS BAHAYA EROSI DAN ARAHAN PENGGUNAAN LAHAN PADA DAS MAREK DS BAGIAN HULU KABUPATEN BONE
Authors: Arifin Muhammad Zainal , Boceng Annas , Saida Saida 
Published: October 2023

This study aims to analyze the amount of erosion that occurs and the erosion that can be tolerated in the upstream Marek DS watershed, analyze the erosion hazard index in the upstream Marek DS watershed, and analyze land use in accordance with conservation patterns that can be applied to land due to erosion. This research was conducted using the Universal Soil Loss Equation (USLE) method to determine the level of erosion (A) that occurred at the research site. Make changes to the C and P values to find the right direction for land use. The results show that the average erosion rate that occurs in the upstream Marek DS watershed is the largest on open land, which is 1107,965 tons/ha/year, and the tolerable erosion is 17,832 tons/ha/year on dry land mixed with shrubs. It amounted to 652.297 tons/ha/year and the tolerable erosion was 20,592 tons/ha/year. The erosion in shrubs was 613.999 tons/ha/year and the tolerable erosion was 17.456 tons/ha/year. The tolerable erosion rate in secondary dryland forest was 11,372 tons/ha/year and the rate of erosion was 17,103 tons/ha/year. The smallest erosion on rice fields was 0.125 tons/ha/year and the tolerable erosion was 29,275 tons/ha/year. The average erosion hazard index in the upstream Marek DS watershed has a low value of 0.280% or 10,822 ha, namely in paddy fields; a moderate value of 5.671% or 219.079 ha, namely in secondary dryland forest, and a very high value, respectively, on dry land. Dry land agriculture mixed with shrubs accounts for 48.102% (or 1858.305 ha), open land accounts for 0.779% (or 30.083 ha), and dry land agriculture mixed with bushes accounts for 45.168% (or 1744.942 ha).Recommendations for land use directions in the upstream Marek DS watershed in the form of natural forest with lots of litter in secondary dryland forest and shrubs, then recommendations for medium density mixed gardens and making bench terraces on open land, and finally recommendations for high-density mixed gardens and making bench terraces for agriculture. If natural forest is mixed with shrubs and shrubs, then the recommendation for natural forest is less litter on open land.
How to manage symptoms in pediatric cancer patients enrolled in clinical trials? A review of principal patient-reported outcome screening tools
Authors: Zucchetti Giulia , Cagnazzo Celeste , Ciappina Sabrina , Bertorello Nicoletta , Resente Francesca , Spadea Manuela , Ceolin Valeria , Fagioli Franca 
Published: October 2023

Background: In adult oncology, the practice of tracking symptoms and toxicities using patient-reported outcomes (PROs) has increased and correlates with increased survival. In contrast, symptom monitoring using PROs is not common in pediatric oncology. Only in the last couple of years attention has also been paid to the patient’s perception in pediatrics and listening to the voice of children and to making them participate in the treatment.
Methods: A comprehensive literature search was conducted in MEDLINE/PubMed and PsycINFO to identify relevant articles published through December 2022.
Results: From 58 non-duplicate articles, 33 met our eligibility criteria. Of these, 17 were used in clinical trials.
Conclusions: The dissemination and use of these tools will therefore have surprising repercussions on the control of pain and physical symptoms of small patients as well as on physical and psychological aspects. The administration and use of the PROs ensures optimal use of the drugs currently present in clinical trials by researcher and nurse and aims at a safer and more controlled approval of new drugs.
Avaliação dos níveis de ansiedade e depressão em mães de crianças com TEA (Transtorno do Espectro Autista) e seus fatores associados
Authors: Moreira Ana Lídia Corrêa da Silva , Lopes Karla Zengo Santana , Paulo Renata Ferreira Araujo Nogueira de 
Published: October 2023

Introdução: O Transtorno do Espectro Autista (TEA) é uma condição que afeta o neurodesenvolvimento, causando déficits das habilidades de comunicação, socialização e adaptação ao ambiente externo. O cuidado de crianças com TEA exige mudanças na vida de toda família, gerando ao cuidador uma sobrecarga física e emocional. As mães são as principais responsáveis pelo filho, logo são as que mais sofrem de transtornos de ansiedade, depressão e estresse crônico. Objetivo: Avaliar ansiedade e depressão em mães de filhos com TEA e fatores associados a essa prevalência. Métodos: contará com mães de crianças autistas que participarão da pesquisa, por Google Forms dos questionários Patient Health Questionnaire-9 (PHQ-9) e Transtorno Geral de Ansiedade (GAD-7). Resultados: O PHQ-9 identificou que a média padrão entre as participantes foi de 13,83 pontos, em que a pontuação máxima foi 27 e mínima 0 pontos. Já no GAD-7 a média da somatória dos pontos entre as participantes foi de 12,63, sendo a maior pontuação 21 pontos e a menor 2 pontos. Conclusão: Os resultados mostram que mães de crianças com TEA apresentam alta incidência de Transtornos Depressivos e de Ansiedade. Além de, estresse, esgotamento físico e emocional, devido a centralização do cuidado nas mães. Ademais, a dependência financeira expõe essas mulheres a situações de vulnerabilidade e violência. Por fim, ressaltamos a necessidade de formulações de ações para esse público-alvo, a fim de melhorar a qualidade de vida dessas mães.
Atlas Identifikasi Tumbuhan Sebagai Media Wisata Edukasi di Taman Botani Kecamatan Sukorambi Kabupaten Jember
Authors: Sudiarti Diah , Hasbiyati Haning 
Published: October 2023

This atlas was compiled based on the result of research on plant identification in the Sukorambi Botanical Garden, Jember Regency. The research results obtained can be developed into a form that is ready to be implemented and utilized by the community. Sukorambi Botanical Garden is a nature tourism park with the concept of recreation while learning. In the Sukorambi Botanical Garden, there are various types of plants and are scattered throughout the area. The Sukorambi Botanical Garden has great potential if it can be used as an educational tour, however, to make it an educational tour, the botanical tourist park is still not equipped with media for education, namely what types of plants are there, so there is a need for a plant identification atlas to make it easier for visitors, especially students, to go on educational tours. Based on the results of this development activity, it was concluded that the plant identification atlas could be used as an educational tourism medium at the Botanical Park, Sukorambi sub-district, Jember district.
Penguatan Ketahanan Pangan di Era Modern
Authors: Rentor Aknes , Rahmawati Rena , Amah Anisa Mbali , Hartatik Sri Fatmaning , Saffanah Winin Maulidya 
Published: October 2023

Abstract
Abstract Food is a source of human energy, with enough food, humans can do many things. Unfortunately, in this modern era in which where farm is limited food security become a problem. Therefore, there should be ways out to solve this problem. One simple thing to improve food security is by functioning the availability of limited land. However not all citizens know how to make use their limited land for food security. To this, our team decide to provide workshop and supervision to maximize limited land to support food security in this modern life. This activity aims to increase the awareness of citizens regarding the importance of utilizing limited land to support food security. This activity was carried out in several stages and with continuous supervision. As a result, residents can utilize their own limited of land. From this workshop. Each house has grown vegetables and fruit to support their daily nutrition. In addition of being economical, citizens find out that their homes feel freshers as they are surrounded by plants
PENGUKURAN KINERJA KARYAWAN PADA PT HT MANUFACTURING
Authors: Anjani Restu , Sugianto Welly 
Published: October 2023

This research focuses on measuring the performance of employees at PT HT Manufacturing, a company producing fishing bait and equipment. The study aims to assess employee performance in the Painting department and identify potential areas for improvement. The current performance measurement system is found to be subjective, emphasizing financial targets only. The theoretical framework discusses the concept of performance, performance measurement, human resources management, and the Human Resource Scorecard (HRSC). The HRSC is an important tool for measuring and managing the strategic contributions of human resources to achieve the company's objectives. The research methodology used is a survey, employing questionnaires and interviews to collect data from 24 employees in the Painting department. Data validity and reliability are tested using statistical analyses like correlation and Cronbach's alpha.
The findings reveal that most indicators used to measure employee performance are valid and reliable. However, one indicator related to measuring performance between employees and their superiors is found to be invalid. The research concludes that the company's performance measurement needs improvement, and employee training plays a crucial role in enhancing job satisfaction and overall performance.Overall, this study provides valuable insights into the performance measurement process at PT HT Manufacturing and offers recommendations for enhancing employee performance and job satisfaction through effective training programs.
ANALISIS PENGENDALIAN KUALITAS PRODUK TLS PADA PT HO WAH GENTING
Authors: Hanyel Hendra , Fajrah Nofriani 
Published: October 2023

ABSTRACT
One of the keys to success in winning industry competition in the future or in the era globalization is to pay attention to quality issue. For that reason, if a company wants to survive, particularly in facing the future, so are required to pay attention to the quality.PT Ho Wah Genting is company operating in manufacturing sector that produces cable wire, by which one product is TLS. According to observation, there were three problems during the printing procces. Malformed product is being, and less product defects. The research on p’s control maps show that there’s data that’s out of control. Based on the analysis of the defect using the fishbone diagram for every flaw there are some factor which are human being. Machines, method, material, and also the neigborhood. Based on the analysis in the field, the product defects cannot be eliminated because when the machine is set up, it will also defect product. Based on the three alternative design tools obtained, the third design alternative was chosen because it is effective in helping operators maintain product quality and in accordance white the constraints faced by operators during the production process.
Effect of whole body vibration therapy in the rat model of steroid-induced osteonecrosis of the femoral head
Authors: Tian Jia-Qing , Wei Teng-Fei , Wei Yu-Rou , Xiao Fang-Jun , He Xian-Shun , Lin Kun , Lu Shun , He Xiao-Ming , He Wei , Wei Qiu-Shi , Xiang Xiao-Wei , He Min-Cong 
Published: October 2023

Background: Steroid-induced Osteonecrosis of the Femoral Head (SIONFH) is a skeletal disease with a high incidence and a poor prognosis. Whole body vibration therapy (WBVT), a new type of physical training, is known to promote bone formation. However, it remains unclear whether WBVT has a therapeutic effect on SIONFH.Materials and methods: Thirty adult male and female Sprague-Dawley (SD) rats were selected and randomly assigned to three experimental groups: the control group, the model group, and the mechanical vibration group, respectively. SIONFH induction was achieved through the combined administration of lipopolysaccharides (LPS) and methylprednisolone sodium succinate for injection (MPS). The femoral head samples underwent hematoxylin and eosin (H&amp;E) staining to visualize tissue structures. Structural parameters of the region of interest (ROI) were compared using Micro-CT analysis. Immunohistochemistry was employed to assess the expression levels of Piezo1, BMP2, RUNX2, HIF-1, VEGF, CD31, while immunofluorescence was used to examine CD31 and Emcn expression levels.Results: The H&amp;E staining results revealed a notable improvement in the ratio of empty lacuna in various groups following WBVT intervention. Immunohistochemical analysis showed that the expression levels of Piezo1, BMP2, RUNX2, HIF-1, VEGF, and CD31 in the WBVT group exhibited significant differences when compared to the Model group (p &lt; 0.05). Additionally, immunofluorescence analysis demonstrated statistically significant differences in CD31 and Emcn expression levels between the WBVT group and the Model group (p &lt; 0.05).Conclusion: WBVT upregulates Piezo1 to promote osteogenic differentiation, potentially by enhancing the HIF-1α/VEGF axis and regulating H-vessel angiogenesis through the activation of the Piezo1 ion channel. This mechanism may lead to improved blood flow supply and enhanced osteogenic differentiation within the femoral head.
Efficacy of prognostic nutrition index in combination with D-dimer in predicting postoperative clinical adverse events after acute type A aortic dissection: a single center retrospective study
Authors: Xie Linfeng , He Jian , Lin Xinfan , Zhang Zhaofeng , Zhuang Xinghui , Jiang Debin 
Published: October 2023

BackgroundThe aim of this study was to identify the predictive factors for adverse clinical events after surgery in patients with acute type A aortic dissection (AAAD), and to explore the predictive value of preoperative prognostic nutritional index (PNI) combined with D-dimer for these events.MethodsThis study was a retrospective analysis of clinical data of 153 patients with AAAD who underwent emergency surgery at our center from January 2019 to January 2022. Patients were divided into adverse event group and non-adverse event group based on whether they experienced adverse clinical events after surgery. Univariate and multivariable logistic regression analyses were performed to identify the risk factors for adverse events, and the predictive efficacy was evaluated by the area under the receiver operating characteristic curve (ROC-AUC).ResultsA total of 153 AAAD patients were included in the study, and were divided into the adverse event group (n = 46) and the non-adverse events group (n = 107) based on whether or not they experienced clinical adverse events after surgery. The optimal cutoff value was determined using ROC curves, and multivariate logistic regression analysis was performed. Ultimately, it was found that preoperative PNI &lt; 42.45 and D-dimer &gt; 15.05 were independent predictors of postoperative clinical adverse events in AAAD patients. The odd ratios (OR) value for preoperative PNI &lt; 42.45 is 3.596 [95% Confidence Interval (CI): 1.508–8.923, p = 0.004], while the OR value for D-dimer &gt; 15.05 is 7.572 [95% CI: 3.094–20.220, p &lt; 0.001]. The combination of these two indicators has a high predictive value (AUC = 0.843, 95% CI: 0.774–0.912, p &lt; 0.001) and is superior to using either variable alone.ConclusionPreoperative PNI &lt; 42.45 and D-dimer &gt; 15.05 are independent predictive factors for postoperative adverse events during hospitalization in patients with AAAD. The combination of these two indicators can improve the predictive accuracy, which is superior to using either variable alone.
Tailored pharmacist-led intervention to improve adherence to Iron supplementation in premature infants: a randomized controlled trial in China
Authors: Yu Beimeng , Ni Ming , Li Haijing , Xu Renjie , Wang Aiping 
Published: October 2023

IntroductionPrematurity is due to a number of factors, especially genetics. This study was designed to evaluate the impact of a pharmacist-led patient-centered medication therapy management trial on iron deficiency and medication adherence among premature infants receiving iron supplementation at a tertiary hospital in Shaoxing, China.MethodsIn this randomised controlled trial, eighty-one premature infants, with or without genetic factors, born at 26 to 30 weeks and 6 days gestational age, will be recruited and randomised to an intervention group or a control group. The intervention group will receive a pharmacist-driven discharge counseling on iron supplements from recruitment, until 12 months. The control group will receive care as usual. The main outcomes were haemoglobin (g/L), serum iron (μg/L), medication adherence estimation and differentiation scale, the satisfaction with information about medicines scale, beliefs about medicines questionnaire and the Bayley scales for infant development.ResultsA total of 81 patients were enrolled in the study. After intervention, results for the haemoglobin and serum iron differed significantly between the control group and the intervention group (101.36 vs. 113.55, P &lt; 0.0001 and 51.13 vs. 101.36, P = 0.004). Additionally, there was a substantial difference between the intervention group and the control group in terms of patient medication adherence estimation and differentiation scale (27 vs. 34, P = 0.0002). the intervention group had better mental development index and psychomotor development index, compared with the control group (91.03 vs. 87.29, P = 0.035 and 95.05 vs. 90.00, P = 0.022).DiscussionIn premature infants with iron deficiency, our pharmacist-led team significantly improved clinical outcomes and medication adherence.
Loss of NOD2 in macrophages improves colitis and tumorigenesis in a lysozyme-dependent manner
Authors: Chauvin Camille , Radulovic Katarina , Boulard Olivier , Delacre Myriam , Waldschmitt Nadine , Régnier Paul , Legris Gauthier , Bouchez Clément , Sleimi Mohamed-Yassine , Rosenstiel Philip , Darrasse-Jèze Guillaume , Chamaillard Mathias , Poulin Lionel F. 
Published: October 2023

BackgroundCrohn’s disease (CD) is a complex and poorly understood myeloid-mediated disorder. Genetic variants with loss of function in the NOD2 gene confer an increased susceptibility to ileal CD. While Nod2 in myeloid cells may confer protection against T-cell mediated ileopathy, it remains unclear whether it may promote resolution of the inflamed colon. In this study, we evaluated the function of Nod2 in myeloid cells in a model of acute colitis and colitis-associated colon cancer (CAC).MethodsTo ablate Nod2 specifically within the myeloid compartment, we generated LysMCre/+;Nod2fl/fl mice. The role of NOD2 was studied in a setting of Dextran Sodium Sulfate (DSS)-induced colitis and in azoxymethane (AOM)/DSS model. Clinical parameters were quantified by colonoscopy, histological, flow cytometry, and qRT-PCR analysis.ResultsUpon DSS colitis model, LysMCre/+;Nod2fl/fl mice lost less weight than control littermates and had less severe damage to the colonic epithelium. In the AOM/DSS model, endoscopic monitoring of tumor progression revealed a lowered number of adenomas within the colon of LysMCre/+;Nod2fl/fl mice, associated with less expression of Tgfb. Mechanistically, lysozyme M was required for the improved disease severity in mice with a defect of NOD2 in myeloid cells.ConclusionOur results indicate that loss of Nod2 signaling in myeloid cells aids in the tissue repair of the inflamed large intestine through lysozyme secretion by myeloid cells. These results may pave the way to design new therapeutics to limit the inflammatory and tumorigenic functions of NOD2.
Reported adverse events during out-of-hospital mechanical ventilation and ventilatory support in emergency medical services and critical care transport crews: a systematic review
Authors: Pinto-Villalba Ricardo Sabastian , Leon-Rojas Jose E. 
Published: October 2023

BackgroundEmergency medical services (EMS) and critical care transport crews constantly face critically-ill patients who need ventilatory support in scenarios where correct interventions can be the difference between life and death; furthermore, challenges like limited staff working on the patient and restricted spaces are often present. Due to these, mechanical ventilation (MV) can be a support by liberating staff from managing the airway and allowing them to focus on other areas; however, these patients face many complications that personnel must be aware of.AimsTo establish the main complications related to out-of-hospital MV and ventilatory support through a systematic review.MethodologyPubMed, BVS and Scopus were searched from inception to July 2021, following the PRISMA guidelines; search strategy and protocol were registered in PROSPERO. Two authors carried out an independent analysis of the articles; any disagreement was solved by mutual consensus, and data was extracted on a pre-determined spreadsheet. Only original articles were included, and risk of bias was assessed with quality assessment tools from the National Institutes of Health.ResultsThe literature search yielded a total of 2,260 articles, of which 26 were included in the systematic review, with a total of 9,418 patients with out-of-hospital MV; 56.1% were male, and the age ranged from 18 to 82 years. In general terms of aetiology, 12.2% of ventilatory problems were traumatic in origin, and 64.8% were non-traumatic, with slight changes between out-of-hospital settings. Mechanical ventilation was performed 49.2% of the time in prehospital settings and 50.8% of the time in interfacility transport settings (IFTS). Invasive mechanical ventilation was used 98.8% of the time in IFTS while non-invasive ventilation was used 96.7% of the time in prehospital settings. Reporting of adverse events occurred in 9.1% of cases, of which 94.4% were critical events, mainly pneumothorax in 33.1% of cases and hypotension in 27.6% of cases, with important considerations between type of out-of-hospital setting and ventilatory mode; total mortality was 8.4%.ConclusionReported adverse events of out-of-hospital mechanical ventilation vary between settings and ventilatory modes; this knowledge could aid EMS providers in promptly recognizing and resolving such clinical situations, depending on the type of scenario being faced.