bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic efficacy of S-adenosylmethionine in chronic uranium intoxication in rats
Authors: Sivak K. V. , Stosman K. I. , Savateeva-Lyubimova T. N. , Kalinina E. Y. , Rassokha T. A. 
Published: December 2023

Introduction. Chronic exposure to uranium compounds causes adverse cytotoxic and immunopathological effects in the body. The aim of the work was to evaluate the therapeutic efficacy of S-adenosylmethionine when administered intragastrically with respect to hepato-, nephro- and immunotoxic effects in chronic intoxicationwith uranyl acetate dihydrate (UAD). Materials and methods. Chronic intoxication was modeled by injecting 85 male rats with UAD solution (5.0 mg/kg/day by element) for one month. S-adenosylmethionine was administered to animals at a dose of 72.7 mg/kg for 21 days. Results. In chronic poisoning with UAD, 65% lethality, decrease of liver mass ratios (MR) and increase of renal MR were observed. Decrease in alkaline phosphatase activity, glucose level, lactic acid, number of CD4+ T-lymphocytes, increase in lactate dehydrogenase activity and creatinine level, number of CD8+ T-lymphocytes and apoptotic cell death, formation of catabolic pool of low and medium molecular weight substances (LMSMS) of blood plasma were registered. The results of urine analysis revealed the development of hyposthenuria, signs of glucosuria, hematosuria, proteinuria and leukocyturia, appearance of bilirubin in the urine. S-adenosylmethionine contributed to the decrease in the degree of target organ damage (reduction of fibroplastic and dystrophic changes in the liver and kidneys), normalization of immune system parameters (increase in CD4+ T-cells, decrease in CD8+ T-cells and frequency of apoptotic death of lymphocytes in immunocompromised animals) and endotoxicosis (decrease in the level of LMSMS from the catabolic pool area). Discussion. According to the totality of all revealed pathological changes, UAD poisoning led to the development of tubulointerstitial nephritis, metabolic disorders of detoxification functions of the liver. The causes of animal death during the first week of the experiment were acute kidney damage or confluent pneumonia. The appearance of bilirubin in the urine was associated with porphyrin metabolism disorders. In the remote period of intoxication an imbalance of the T-cell link of the immune system developed, as well as, probably, a decrease in nonspecific resistance, which led to the development of pneumonia in rats. Conclusion. S-adenosylmethionine therapy of hepato-, nephro- and immunotoxic effects in chronic UAD intoxication contributed to a decrease in the degree of damage to target organs, normalization of immune system parameters and endogenous intoxication.
Avoiding Medication Errors Caused by Nurses in the Emergency Department in Saudi Arabia
Authors: Ahmed Yasir , Alhasson Alkhuzama Hasson , Mahrus Waladin Faiz , Asiri Talal Marui , Alsuwayed Sara ahmed , Alturki Alaa Turki , Alzoman Moneerah Mohammed , Alobaid Kassem Jawad 
Published: December 2023

Background: Medication errors are pervasive in healthcare, especially in emergency rooms, with diverse causes that warrant critical investigation due to the potential repercussions for both patients and healthcare providers.
Aim: This research explores nurses' perspectives on medication errors in the emergency department.
Methods: A descriptive cross-sectional design involved 96 nurses, using a questionnaire that covered demographic data and nurses' perceptions of error causes, reporting practices, and barriers.
Results: The average age of the nurses who participated in this study was 27.7 ± 3.4 years, with 7.3 ± 1.9 years of experience. Most nurses (87.2%) were women. The majority held bachelor's degrees (88.3%) and worked fixed shifts (54.2%), and 46.8% reported medication errors in the past year, primarily occurring once (69.04%). They reported no complications in 97.5% of errors.
Conclusion:
Common error types included infusion rate errors, double dosing, and medication omission. Although errors are widespread, adverse consequences are infrequent, mainly occurring during prescribing or administration stages. Encouraging disclosure by nurses and fostering positive responses from hospital management are crucial for enhancing patient safety. Awareness of recovery mechanisms informs potential interventions to minimise overall safety.
Key words: Medication Errors, Emergency Department, Nurses, Understanding, Perception
HUBUNGAN AKSES AIR MINUM DAN SANITASI PADA KELUARGA DENGAN KEJADIAN STUNTING: SCOPING REVIEW
Authors: Nur'aeni Nabyla 
Published: December 2023

Introduction: Water and soil have a role in the transmission of disease. Cases of malnourished children under five have the potential to increase due to inadequate latrine facilities and drinking water quality. This review aims to decide the relationship between family access to drinking water and sanitation and the incidence of stunting to analyze the next prevention.
Methods: The approach taken is a scoping review by identifying articles in PubMed, CINAHL, and Sage from 2012-2022. The keywords used were "family, clean water and sanitation, stunting" developed with the PICO framework.
Result: Five articles were included in the analysis. Three of the five studies concluded a significant association between family access to drinking water and sanitation and the incidence of stunting. This was also related to the management and storage of water for drinking and family hygiene behaviors.
Conclusion: Access to drinking water and sanitation is associated with stunting. Interventions are needed not only in infrastructure development to provide access to clean water and affordable latrines but also to increase public awareness.
HUBUNGAN STRES KERJA DENGAN KUALITAS KEHIDUPAN KERJA PERAWAT DI RSUD dr. R. GOETENG TAROENADIBRATA PURBALINGGA
Authors: Konitasari Rizky Rofiana , Sumarni Tri , Kurniawan Wahyu Eko 
Published: December 2023

Introduction: Quality of work life is something that a person achieves in his work. When workers' needs fulfilled, it will have a positive impact on increasing organizational productivity. Work stress, in this case, is an environmental change that causes tension that excessively affects physical and psychological conditions. The aim of this research is to understand the relationship between work pressure and the quality of work life that occurs among nurses who work at RSUD dr. R. Goeteng Taroenadibrata Purbalingga.
Methods: Quantitative method with a cross sectional approach. The respondents in this study were 96 nurses who met the inclusion criteria. This research uses a probability sampling method that has been adjusted proportionally with the stratified random sampling technique. The reference used in this research is the Expanded Nursing Stress Scale and Quality of Work Life. The statistical analysis used is the Spearman Rank test.
Result: The results obtained from data collection shown that the work stress experienced by nurses was mostly in the moderate category (62.5%), and the quality of work life of the nurses was mostly in the high category (53.1%). The result of the overall data analysis is that there is a relationship between work stress and the quality of work life for nurses with a p value of 0.026 (p<a).
Conclusion: There is a relationship between work stress and the quality of work life for nurses at RSUD dr. R. Goeteng Taroenadibrata Purbalingga.
HUBUNGAN KUALITAS TIDUR DENGAN DERAJAT HIPERTENSI DI POSBINDU DESA PANERUSAN WETAN BANJARNEGARA
Authors: Ardina Catur Putri , Haniyah Siti , Kurniawan Wasis Eko 
Published: December 2023

Introduction: The incidence of hypertension in Central Java, 8,700,512 persons, or 30.4% of the population, have hypertension by the time they are over 15 years old in 2021. Based on the results of measurements on residents aged 18 years and over according to characteristics in Central Java, the highest was in the female sex (40.17%) compared to the male sex (34.17%). Some of the risk factors that lead to hypertension include genetic factors, gender, age, diet, obesity, and lifestyle such as smoking and consuming alcohol. Sleep quality plays an important role for every individual in maintaining sleep conditions and achieving the right REM and NREM sleep stages. The aim of these findings is to identify the characteristics of respondents, characteristics of the degree of hypertension, sleep quality and analyze the relationship between sleep quality and degree of hypertension.
Methods: This research applies quantitative through a non-experimental design, data collected using a cross-sectional approach, the total population is 120 respondents with a sample size of 92 respondents.
Result: The results of this study indicate that 70 respondents (76,1%) experienced poor sleep quality. In mild hypertension, there were 43 respondents (46.7%).
PENGGUNAAN VIRTUAL REALITY PADA PASIEN DI RUANG INTENSIVE CARE UNIT (ICU) : SEBUAH TINJAUAN LITERATUR
Authors: Khairunisa Prima , Herawati Tuti 
Published: December 2023

Background: In addition to physical issues, the critical condition that the ICU patients experience also causes a psychological impact that lasts until they leave the ICU treatment. Virtual reality is one of the latest innovations utilized to support the treatment in the ICU. Virtual reality is one of the supporting tools in non-pharmacology interventions to reduce anxiety, stress, and sleep deprivation, as well as mitigate post-traumatic disorder syndrome or PTSD. The research aims to describe the framework for utilizing virtual reality to reduce anxiety, stress, and sleep deprivation, as well as mitigate post-traumatic disorder syndrome. As well as to see how feasible it is to utilize this technology from the security and usage tolerance perspective.
Method: The methode was a literature review. The author search the articles on Google Scholar by filtering search results based on the publication year, article title, and abstract. The research resulted in ten articles to be the literature review.
Result: The search result found ten articles discussing virtual reality on ICU patients as an intervention to reduce anxiety, pain, and sleep deprivation. The research also found that it is feasible to use Virtual reality as an intervention media. From the safety perspective, the technology is safe due to being regularly disinfected and not affecting other life-support tools that the patients need. It also has minimum side effects during usage.
Conclusion: Virtual reality is effective in reducing anxiety, pain, and sleep deprivation in ICU patients. From the safety viewpoint and usage tolerance, the technology is safe and feasible for ICU patients.
Recent advancements in laboratory automation technology and their impact on scientific research and laboratory procedures
Authors: Omair Abdullah Omar Mohammed , Jabbar Abeer Mohammed Abdul , Albulushi Mustafa Othman 
Published: December 2023

This article examines the latest developments in laboratory automation technologies and their influence on scientific research and laboratory protocols. The research examines the incorporation of robotic sample handling systems, artificial intelligence and machine learning algorithms, sophisticated software and hardware, and safety improvements in laboratory automation systems. The research emphasizes the advantages of laboratory automation technologies, such as improved efficiency, repeatability, and safety in the laboratory setting. The study also examines the ramifications of automation technology on scientific research, including the hastening of scientific advancements and the creation of innovative remedies and cures. Moreover, the study highlights the obstacles linked to the adoption of sophisticated automation systems, such as the financial and intricate nature of these systems, and the need for specialized education and proficiency. The review further outlines potential future developments in laboratory automation technology, including continued progress in robotics, artificial intelligence, and microfluidics. It also highlights the potential integration of automation technology with new disciplines like synthetic biology and precision medicine. In summary, the research emphasizes the significant impact of laboratory automation technologies in pushing the boundaries of scientific knowledge and innovation.
The Effects of Advertisements on Influencing Decisions to Invest in Riskier Financial Assets
Authors: Honadi Winston , Johan Jeremy Christo 
Published: December 2023

This research’s main purpose is to discover whether psychological and social factors have a significant effect on a person’s attitudes toward advertisement, ultimately affecting their investment decisions. This research utilized GOTO Stockbit’s advertisement and was distributed to the public Indonesian population who has an interest in investment. The research collected a total of 115 samples which were then filtered to only include those who had experience investing to test the possibility of investing in a riskier financial asset. The research results show that psychological factors had no significant effects on attitudes toward advertisements. However, social factor has a significant enough effect on attitudes toward advertisement, as do attitudes toward advertisement toward investment decision. The study results that social factors lead to a positive attitude toward advertisements from securities that motivate individuals to make an investment decision. However, this study’s results show that psychological factors do not lead to any investment decisions by individuals as it has little to no effect on their attitude toward advertisements. This research aims to measure the effectivity of security advertisements on the investment decisions of individuals by adding a new study goal by introducing new hypotheses involving psychological and social factors to add clarity to previous research covering investment decisions. This research hopes that security brokerage can make an effective and optimal advertisement suggested in the research.
جمالیات سے متعلق نصیر احمد ناصر کے نظریات :"حسنِ تفسیر" کا اختصاصی مطالعہ
Authors: Tahira Munawar  , Tooba Khalid Noori  , Saba Aorangzaib  
Published: December 2023

Aesthetic is concerned with beauty or the appreciation of beauty. It is used to talk about beauty or art and people’s appreciation of beautiful things. Its value can be defined as sensation or feeling of enjoying beauty. Every human will have the value of aesthetics or aesthetic sense that one get to enjoy whatever he sees in his daily life. As a study it aims at the understanding of beauty that is prescribed in front of us. It is not just expressing, enjoying beauty our inner emotions are connected to pursuit of beauty in all its means. In this article Dr. Naseer Ahmad Nasir view on Aestheticism are described who is a notable Islamic Scholar & philosopher from Pakistan. He wrote numerous books on aesthetics including Husn- e -Tafseer in three volumes. His important contribution to philosophy was research on Aesthetics. He tries to explore the Holy Quran with reference of Philosophy of Aesthetics. He claims that it is a unique effort because his work is matchless throughout the Muslim World. Actually, aesthetic is successful attempt to view and to discover the beauty of universe. Human being is part of its beauty and Holy Quran invites this creature to create a very beautiful society to live in. He tries to put before the world this aspect of Holy Quran.
An Introductory Study of Modern Interpretations of the Quran
Authors: Dr. Abdul Hameed  , Mian Saadat Ali Nadeem  , Mr. Nawazish Ali Nadeem  
Published: December 2023

The twentieth century A.D was a very important period for Muslims in Pakistan and India. In the Western world, that universal revolution had reached its culmination, as a result of which modern man, instead of Allah himself, reorganized the whole world of thought and action based on inductive science. The tenets of religion that seemed to contradict the new conception of life were abandoned, and with this state of mind, the Western nations gained political supremacy over the Eastern countries. Doubt, atheism and secularism began to take shape here as well. This was due to the attacks on Islam by Western Christianity and Western-nurtured Orientalism. These attacks on Western thought and Christianity were taking place under the auspices of the imperialist powers. At the same time, these nations were teaching civilization to the eastern nations. Muslim subcontinent was undergoing a process of political and cultural influence. In the field of knowledge, these things affected his intellectual perseverance and resilience in the field of knowledge. A trend of liberalism and reconciliation emerged in the religious literature of the time, represented by Sir Syed Ahmad Khan. After the establishment of Pakistan, some people with the same mindset came forward who expressed their commitment and deep connection with the Qur’ān, He wrote many books and published journals to popularize Qur’ānic teachings. He taught Qur’ānic discourses and wrote commentaries, but through the maneuvering, and misinterpretation of the Qur’ānic verses, he developed the structure of an Islam whose features were radically different from the real Islam.
"رواج نامۂ سوات" میں موجود مویشیوں کی زکوۃ کے متعلق والئی سوات کے قوانین کا شرعی و تحقیقی جائزہ
Authors: Saifullah  , Dr. Lutfullah Saqib  , Dr. Saeed ur Rahman  
Published: December 2023

Zakāt is a financial liability imposed by Sharī’ah (Islamic law) on believers. The legality of such obligation, of course, is derived from several verses of the Holy Qurān and Ḥadīth of the Holy Prophet (SM). Such obligation, in terms of its substance, can be divided, mainly, in currencies and animals. The latter kind, being a complex one, has been elaborated by Islamic law with minute details. Additionally, head of the state has the responsibility to make necessary arrangements for the management of such financial obligation- ranging from the collection to the division. Wālī Swat (a famous ruler of Swat), being a head of the Swat State, fulfilled this responsibility in the best possible way. At his time, a very unique system was introduced for the collection of Zakāt (from those individual having Nisāb for the same). The contemporary Sharī’ah scholars have a difference of opinion whether such mechanism, introduced for the collection of Zakat, was entirely based on Sharī’ah or not. The present work, following this question, aims to find out the best possible answer to it. While doing so, all verdicts, related to the issue under consideration, have been analyzed for the perspective of Islamic law. The work of the classical Muslim jurists (fuqahā) has been citied extensively; while analyzing a verdict. The Hanfī school of thought, however, has been offered more comparatively to other school of thought- owing to the fact that the legal system, prevailing in the regime of Wālī Swat, was, predominantly, based on the principles of the same school. Further, content analysis technique, a kind of qualitative research has been adopted for the investigation of the issue.
EFEITOS DA CORREÇÃO ATMOSFÉRICA EM IMAGENS MULTIESPECTRAIS ORBITAIS PARA ESTUDOS EM CORPOS D’ÁGUA INTERIORES
Authors: Segedi Gabriella Correa , Cicerelli Rejane Ennes , Almeida Tati , Roig Henrique Llacer , Olivetti Diogo , Bernardi José Vicente Elias , Castreghini Adriana 
Published: December 2023

Os reservatórios hídricos além de serem importantes para a produção de energia elétrica, são recursos para outras necessidades da população. Imagens de sensores orbitais são aplicadas para complementar o monitoramento desses ambientes e assim suprir a deficiência de cobertura espacial e temporal das técnicas tradicionais. No entanto estudos envolvendo análises volumétricas de corpos d’água ainda são um grande desafio devido ao baixo sinal proveniente do corpo d’água e a interferência de fatores externos (ou fatores ambientais). Procedimentos de correção/melhoramento das imagens são propostos com frequencia, principalmente para a redução da interferencia atmosférica. Nesse estudo foram avaliadas as melhores técnicas de correção atmosférica disponíveis comercialmente no intuito de indicar aquela técnica que mais se aproxima da resposta espectral de sensoriamento remoto obtida em campo (referência). No decorrer do estudo foram aplicados seis algoritmos de correção atmosférica (FLAASH, Second simulation of a Satellite Signal in the Solar Spectrum (6S), L8SR, Aquatic Reflectance (USGS), ACOLITE e Sen2Cor) que, a partir das análises estatísticas de análise discriminante e covariância apontaram os aplicativos 6S para imagens Landsat e Sentinel e o Acolite para imagens Landsat como os mais acurados. Embora o 6S tenha apresentado resposta próxima dos dados de referencia, observou-se baixa variabilidade na resposta espectral. Para séries temporais, o Acolite apresentou maior capacidade de correção dos dados. O tipo de aplicação também é um fator preponderante, pois ficou evidente que o uso de series temporais indicou uma técnica de correção atmosférica diferente quando comparado com a análise das cenas de forma individual.
Does Reflexology Reduce Birth Pain? A Systematic Review
Authors: AY Fatma , AGHIL DIZAJ Pooneh 
Published: December 2023

Objectives: In this systematic review, we aim to evaluate the efficacy of foot reflexology method on pain intensity of labor.
Material-Method: The study was done in the second half of 2019 PubMed (MEDLINE), CINAHL (EBSCO), Scopus, Science Citation Index, Science Direct, ULAKBIM (Turkish National Databases) databases were searched using terms and keywords including ‘labor pain’ ‘vaginal delivery’ ‘normal delivery’ ‘pregnancy and delivery’ ‘reflexology’ ‘foot massage’ ‘pain and reflexology’ in three languages.
Results: Out of a total of 3292 articles found from databases, 9 articles that had inclusion criteria were included in the study. Studies have shown that foot reflexology during labor reduces the severity of labor pain.
Conclusions: Performing foot reflexology as one of the low-risk and low-cost methods of pain relief can be an effective method in reducing pain and duration of labor. It is recommended that more adequately powered studies be done in this area.
Determination of Nurses' Attitudes Towards the Use of Traditional and Complementary Medicine in Children: A Comparative Study
Authors: SARMAN Abdullah , TUNCAY Suat 
Published: December 2023

Objective: In this study, it was aimed to determine the attitudes of nurses towards the use of T&CM practices in children.
Material-Method: This study was designed in a cross-sectional-comparative descriptive design. The study fieldwork was conducted between May and August 2023. Nurses working in a hospital providing secondary health care in eastern Turkey were included in the study. Demographic data of nurses and their attitudes towards holistic complementary and alternative medicine were analysed.
Results: It was determined that the mean age of the participants was 33.92 years and 69% of them worked in a state hospital. It was also found that 25.4% of the nurses had used T&CM before, and the most used T&CM method was cupping or leeching with 38.5%. Of those who participated in the study and had previously used T&CM practices, 63.5% reported that they recovered with these practices and 84.6% reported that they recommended the method they used to others. It was determined that 51% of the nurses thought that T&CM practices could be used in children and the most common T&CM method that was thought to be used in children was homeopathy with 50.7%.
Conclusion: It was determined that pediatric nurses had a more positive attitude towards T&CM. It was observed that nurses thought that T&CM interventions could be used safely in the treatment of children. Since information about T&CM is obtained from newspapers, magazines, or media programmes, it is thought that integrating T&CM into nursing education curricula may be effective in raising awareness.