bluuebunny/crossref_metadata_2025_split huggingface dataset:
How the first revolution affected the second: The setback of 1927 for the Chinese Communist Party Revolution in the 1920s
Authors: Zhou Luyang 
Published: October 2023

AbstractThe Bolsheviks’ world revolution encountered setbacks in the 1920s. Among the bloodiest of these was the massacre of 1927 when the Chinese Communist Party’s (CCP) entire central leadership was killed in the Chinese Nationalist Party’s (GMD) coup. Existing explanations highlight Moscow’s miscalculation, infighting within the Kremlin, Soviet advisers’ information dilemma, and the CCP leaders’ political inexperience. This article compares the opening stages of the Bolshevik (or Russian) and Chinese Communist Party revolutions to explain why the 1927 setback became a catastrophe. It argues that the Bolshevik Revolution of 1917 caused fundamental changes, which thwarted any attempt to replicate the 1917 victory in the post-1917 world. The CCP in 1927 faced three disadvantages that the Bolshevik Revolution had engendered: a misleading myth about the October Revolution, a Bolshevized system of repression created by Soviet advisers to the GMD, and the ‘red scare’ in Japan and British Southeast Asia, which blocked members of the CCP from escaping overseas. This article draws on leaders’ biographical materials to compare the two parties’ learning from foreign revolutions, records in suffering repression, and experiences as overseas refugees. The comparison shows that the Bolsheviks did not face these three disadvantages before 1917.
What do infants need an ownership concept for? Frugal possession concepts can adequately support early reasoning about distributive dilemmas
Authors: Tatone Denis 
Published: October 2023

Abstract
Boyer's model posits that ownership intuitions are delivered by combining input representations of resource conflict and cooperative value, necessary to solve coordination dilemmas over resource access. Here I evaluate the implications of this claim for early social cognition and argue that cognitively frugal possession concepts can be leveraged to the same inferential end, making the ascription of ownership proper unnecessary.
Development, history, and a minimalist model of ownership psychology
Authors: Noles Nicholaus Samuel 
Published: October 2023

Abstract
Boyer's minimalist model is a compelling account of ownership psychology that is more efficient than previous models. However, it is unclear whether the two simple systems that make up this model – acquisitiveness and cooperation – are sufficient to both explain the nuanced development of ownership concepts and to account for the prominent influence that history has on ownership psychology.
Beyond personal ownership: Examining the complexities of ownership in culture
Authors: Belk Russell W. , Atasoy Özgün 
Published: October 2023

Abstract
We argue that ownership is a highly flexible concept, shaped by both innate and learned aspects, and heavily influenced by culture. Boyer's model focuses solely on universal personal ownership, neglecting other forms such as shared ownership, fractionalized property rights, and the ownership of the meanings and memories attached to possessions. A comprehensive understanding requires considering diverse human relationships with objects.
Hold it! Where do we put the body?
Authors: Wispinski Nathan J. , Enns James T. , Chapman Craig S. 
Published: October 2023

Abstract
Boyer's formulation neglects that humans are embodied agents. It is a biological imperative to distinguish self from other. Ownership of ideas, bodies, objects, and locations is an inevitable extension of this. We argue that (1) the body's capability influences the inputs that guide future actions, and (2) bodies in action influence all of cognition, from perception to decision making.
Invested effort and our open-ended sense of ownership
Authors: Merker Bjorn 
Published: October 2023

Abstract
Pascal Boyer achieves a felicitous integration of what is known about human ownership psychology by deriving ownership intuitions from the interaction of resource acquisition and our cooperative sociality. By exploring the sense of ownership already present in the domain of resource acquisition, I sketch an evolutionary path to the open-ended nature of the specifically human version of that sense.
Ownership psychology as a “cognitive cell” adaptation: A minimalist model of microbial goods theory
Authors: Clark Kevin B. 
Published: October 2023

Abstract
Microbes perfect social interactions with intuitive logics and goal-directed reciprocity. These multilevel, cognition-resembling adaptations in Dictyostelid cellular molds enable individual-to-group viability through public/private bacterial farming and dynamic marketspaces. Like humans and animals, Dictyostelid livestock-ownership depends on environmental sensing, cooperation, and competition. Moreover, social-norm policing of cosmopolitan colonies coordinates farmer decisions, phenotypes, and ownership identities with bacteria herding, privatization, and consumption.
STING activation in TET2-mutated hematopoietic stem/progenitor cells contributes to the increased self-renewal and neoplastic transformation
Authors: Xie Jiaying , Sheng Mengyao , Rong Shaoqin , Zhou Dan , Wang Chao , Wu Wanling , Huang Jingru , Sun Yue , Wang Yin , Chen Pingyue , Wu Yushuang , Wang Yuanxian , Wang Lan , Zhou Bo O. , Huang Xinxin , Walsh Colum P. , Bohlander Stefan K. , Huang Jian , Wang Xiaoqin , Xu Guo-Liang , Gao Hai , Shi Yuheng 
Published: October 2023

AbstractSomatic loss-of-function mutations of the dioxygenase Ten-eleven translocation-2 (TET2) occur frequently in individuals with clonal hematopoiesis (CH) and acute myeloid leukemia (AML). These common hematopoietic disorders can be recapitulated in mouse models. However, the underlying mechanisms by which the deficiency in TET2 promotes these disorders remain unclear. Here we show that the cyclic guanosine monophosphate-adenosine monophosphate synthase (cGAS)-stimulator of interferon genes (STING) pathway is activated to mediate the effect of TET2 deficiency in dysregulated hematopoiesis in mouse models. DNA damage arising in Tet2-deficient hematopoietic stem/progenitor cells (HSPCs) leads to activation of the cGAS-STING pathway which in turn promotes the enhanced self-renewal and development of CH. Notably, both pharmacological inhibition and genetic deletion of STING suppresses Tet2 mutation-induced aberrant hematopoiesis. In patient-derived xenograft (PDX) models, STING inhibition specifically attenuates the proliferation of leukemia cells from TET2-mutated individuals. These observations suggest that the development of CH associated with TET2 mutations is powered through chronic inflammation dependent on the activated cGAS-STING pathway and that STING may represent a potential target for intervention of relevant hematopoietic diseases.
Human milk oligosaccharides modify the strength of priority effects in the Bifidobacterium community assembly during infancy
Authors: Laursen Martin F , Roager Henrik M 
Published: October 2023

Abstract
Despite the significant role of the gut microbiota in infant health and development, little is known about the ecological processes determining gut microbial community assembly. According to ecology theory, the timing and order of arrival of microbial species into an ecosystem affect microbial community assembly, a phenomenon termed priority effects. Bifidobacterium species are recognized as highly abundant early colonizers of the infant’s gut, partly due to their ability to selectively utilize human milk oligosaccharides (HMOs) from breast milk. However, the role of priority effects in Bifidobacterium community assembly remains unclear. Here, we investigated the Bifidobacterium community assembly in the gut of 25 breastfed Danish infants longitudinally sampled throughout the first 6 months of life. Our results showed that the breastfed infants were often initially, but temporarily, dominated by suboptimal HMO-utilizing Bifidobacterium taxa, such as B. longum subsp. longum, before more efficient HMO-utilizers such as B. longum subsp. infantis, replaced the first colonizer as the dominant Bifidobacterium taxon. Subsequently, we validated this observation using gnotobiotic mice sequentially colonized with B. longum subsp. longum and B. longum subsp. infantis or vice versa, with or without supplementation of HMOs in the drinking water. The results showed that in the absence of HMOs, order of arrival determined dominance. Yet, when mice were supplemented with HMOs the strength of priority effects diminished, and B. longum subsp. infantis dominated regardless of colonization order. Our data demonstrate that the arrival order of Bifidobacterium taxa and the deterministic force of breast milk-derived HMOs, dictate Bifidobacterium community assembly in the infant’s gut.
Coalescence of Al0.3CoCrFeNi polycrystalline high-entropy alloy in hot-pressed sintering: a molecular dynamics and phase-field study
Authors: Guo Qingwei , Hou Hua , Wang Kaile , Li Muxi , Liaw Peter K. , Zhao Yuhong 
Published: October 2023

AbstractExisting hot sintering models based on molecular dynamics focus on single-crystal alloys. This work proposes a new multiparticle model based on molecular dynamics to investigate coalescence kinetics during the hot-pressed sintering of a polycrystalline Al0.3CoCrFeNi high-entropy alloy. The accuracy and effectiveness of the multiparticle model are verified by a phase-field model. Using this model, it is found that when the particle contact zones undergo pressure-induced evolution into exponential power creep zones, the occurrences of phenomena, such as necking, pore formation/filling, dislocation accumulation/decomposition, and particle rotation/rearrangement are accelerated. Based on tensile test results, Young’s modulus of the as-sintered Al0.3CoCrFeNi high-entropy alloy is calculated to be 214.11 ± 1.03 GPa, which deviates only 0.82% from the experimental value, thus further validating the feasibility and accuracy of the multiparticle model.
Proteomic meta-study harmonization, mechanotyping and drug repurposing candidate prediction with ProHarMeD
Authors: Adamowicz Klaudia , Arend Lis , Maier Andreas , Schmidt Johannes R. , Kuster Bernhard , Tsoy Olga , Zolotareva Olga , Baumbach Jan , Laske Tanja 
Published: October 2023

AbstractProteomics technologies, which include a diverse range of approaches such as mass spectrometry-based, array-based, and others, are key technologies for the identification of biomarkers and disease mechanisms, referred to as mechanotyping. Despite over 15,000 published studies in 2022 alone, leveraging publicly available proteomics data for biomarker identification, mechanotyping and drug target identification is not readily possible. Proteomic data addressing similar biological/biomedical questions are made available by multiple research groups in different locations using different model organisms. Furthermore, not only various organisms are employed but different assay systems, such as in vitro and in vivo systems, are used. Finally, even though proteomics data are deposited in public databases, such as ProteomeXchange, they are provided at different levels of detail. Thus, data integration is hampered by non-harmonized usage of identifiers when reviewing the literature or performing meta-analyses to consolidate existing publications into a joint picture. To address this problem, we present ProHarMeD, a tool for harmonizing and comparing proteomics data gathered in multiple studies and for the extraction of disease mechanisms and putative drug repurposing candidates. It is available as a website, Python library and R package. ProHarMeD facilitates ID and name conversions between protein and gene levels, or organisms via ortholog mapping, and provides detailed logs on the loss and gain of IDs after each step. The web tool further determines IDs shared by different studies, proposes potential disease mechanisms as well as drug repurposing candidates automatically, and visualizes these results interactively. We apply ProHarMeD to a set of four studies on bone regeneration. First, we demonstrate the benefit of ID harmonization which increases the number of shared genes between studies by 50%. Second, we identify a potential disease mechanism, with five corresponding drug targets, and the top 20 putative drug repurposing candidates, of which Fondaparinux, the candidate with the highest score, and multiple others are known to have an impact on bone regeneration. Hence, ProHarMeD allows users to harmonize multi-centric proteomics research data in meta-analyses, evaluates the success of the ID conversions and remappings, and finally, it closes the gaps between proteomics, disease mechanism mining and drug repurposing. It is publicly available at https://apps.cosy.bio/proharmed/.
Realization of circular polarized multiple band multi-mode OAM antenna using a ring patch for IoT applications
Authors: Fayyaz Umar , Niazi Shahab Ahmad , AlJaloud Khaled , Aziz Abdul , Malik Waqar Ahmad , Hussain Rifaqat 
Published: October 2023

AbstractA multiband and multi-mode antenna with circular polarized conical patterns is suitable for achieving desired spectral efficiency, increased capacity, and spatial diversity for IoT applications. However, simultaneous excitation of such circular polarized multiple Orbital Angular Momentum (OAM) modes through a single patch antenna is challenging due to the complexity of simultaneously fulfilling distinct requirements of each mode. In this paper, a ring patch antenna is designed to excite different OAM states at different frequencies simultaneously. First, characteristic mode analysis is used to analyze the possibility of simultaneous excitation of multiple OAM modes at corresponding frequencies through a simple ring patch antenna. Then, a dual port ring patch antenna is designed and fabricated to verify the capability of generating multiple OAM states at corresponding frequencies. Furthermore, it also presents the guidance to suppress unwanted OAM modes.
Blockchain-based privacy and security model for transactional data in large private networks
Authors: Yakubu Bello Musa , Sabi’u Jamilu , Bhattarakosol Pattarasinee 
Published: October 2023

AbstractCyberphysical systems connect physical devices and large private network environments in modern communication systems. A fundamental worry in the establishment of large private networks is mitigating the danger of transactional data privacy breaches caused by adversaries using a variety of exploitation techniques. This study presents a privacy-preserving architecture for ensuring the privacy and security of transaction data in large private networks. The proposed model employs digital certificates, RSA-based public key infrastructure, and the blockchain to address user transactional data privacy concerns. The model also guarantees that data in transit remains secure and unaltered and that its provenance remains authentic and secure during node-to-node interactions within a large private network. The proposed model has increased the encryption speed by about 17 times, while the decryption process is expedited by 4 times. Therefore, the average overall acceleration obtained was 16.5. Both the findings of the security analysis and the performance analysis demonstrate that the proposed model can safeguard transactional data during communications on large private networks more effectively and securely than the existing solutions.
Changes of cerebral functional connectivity induced by foot reflexology in a RCT
Authors: Descamps Emeline , Boussac Mathilde , Joineau Karel , Payoux Pierre 
Published: October 2023

AbstractNon-Pharmacological Interventions (NPIs) are increasingly being introduced into healthcare, but their mechanisms are unclear. In this study, 30 healthy participants received foot reflexology (FR) and sham massage, and went through a resting-state functional magnetic resonance imaging (rs-fMRI) to evaluate NPIs effect on brain. Rs-fMRI revealed an effect of both NPIs on functional connectivity with changes occurring in the default-mode network, the sensorimotor network and a Neural Network Correlates of Pain (NNCP—a newly discovered network showing great robustness). Even if no differences were found between FR and SM, this study allowed to report brain biomarkers of well-being as well as the safety of NPIs. In further research, it could be relevant to study it in patients to look for a true reflexology induced-effect dependent of patient reported outcomes. Overall, these findings enrich the understanding of the neural correlates of well-being experienced with NPIs and provided insight into the basis of the mechanisms of NPIs.
Antcin-B, a phytosterol-like compound from Taiwanofungus camphoratus inhibits SARS-CoV-2 3-chymotrypsin-like protease (3CLPro) activity in silico and in vitro
Authors: Dakpa Gyaltsen , Kumar K. J. Senthil , Nelen Jochem , Pérez-Sánchez Horacio , Wang Sheng-Yang 
Published: October 2023

AbstractDespite the remarkable development of highly effective vaccines, including mRNA-based vaccines, within a limited timeframe, coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is not been entirely eradicated. Thus, it is crucial to identify new effective anti-3CLPro compounds, pivotal for the replication of SARS-CoV-2. Here, we identified an antcin-B phytosterol-like compound from Taiwanofungus camphoratus that targets 3CLPro activity. MTT assay and ADMET prediction are employed for assessing potential cytotoxicity. Computational molecular modeling was used to screen various antcins and non-antcins for binding affinity and interaction type with 3CLPro. Further, these compounds were subjected to study their inhibitory effects on 3CLPro activity in vitro. Our results indicate that antcin-B has the best binding affinity by contacting residues like Leu141, Asn142, Glu166, and His163 via hydrogen bond and salt bridge and significantly inhibits 3CLPro activity, surpassing the positive control compound (GC376). The 100 ns molecular dynamics simulation studies showed that antcin-B formed consistent, long-lasting water bridges with Glu166 for their inhibitory activity. In summary, antcin-B could be useful to develop therapeutically viable drugs to inhibit SARS-CoV-2 replication alone or in combination with medications specific to other SARS-CoV-2 viral targets.
Risk factor analysis for cisplatin-induced nephrotoxicity with the short hydration method in diabetic patients
Authors: Saito Yoshitaka , Kobayashi Masaki , Tamaki Shinya , Nakamura Katsuyuki , Hirate Daisuke , Takahashi Kenta , Takekuma Yoh , Sakakibara-Konishi Jun , Shimizu Yasushi , Kinoshita Ichiro , Sugawara Mitsuru 
Published: October 2023

AbstractThe occurrence of cisplatin (CDDP)-induced nephrotoxicity (CIN) has decreased with advancements in supportive care. In contrast, we reported that baseline diabetes mellitus (DM) complications significantly worsen CIN. This study aimed to determine further risk factors associated with CIN development in DM patients. Patients with thoracic cancer requiring DM pharmacotherapy, who received CDDP (≥ 60 mg/m2)-containing regimens using the short hydration method (n = 140), were enrolled in this retrospective multicenter observational study. The primary endpoint of the present study was the elucidation of risk factors (patient factors, DM medication influence, and treatment-related factors) associated with CIN development in patients with DM. Cisplatin-induced nephrotoxicity occurred in 22.1% of patients with DM. The median worst variation of serum creatinine levels and creatinine clearance (worst level − baseline level) was 0.16 mg/dL (range: − 0.12–1.41 mg/dL) and − 15.9 mL/min (− 85.5–24.3 mL/min), respectively. Multivariate logistic regression analyses identified female sex as the singular risk factor for CIN development in the DM population (adjusted odds ratio; 2.87, 95% confidence interval; 1.08–7.67, P = 0.04). Diabetes mellitus medication and treatment-related factors did not affect CIN development. In conclusion, our study revealed that female sex is significantly associated with CIN development in patients with DM and thoracic cancer.
Homöopathie und Haut
Authors: Grunow Karl 
Published: October 2023

ZusammenfassungSeit mehr als 200 Jahren hat sich die homöopathische Heilmethode weltweit bei der Behandlung von Krankheiten bewährt. Vor allem bei chronischen sowie therapieresistenten Hautkrankheiten zeigt die homöopathische Behandlung Erfolge, was im Beitrag gezeigt wird. Die Fallbeispiele chronischer Hauterkrankungen stellen die praktische Umsetzung der homöopathischen Arbeitsweise vor. Zu Beginn und nach Abschluss der Therapie fanden Videodokumentationen sämtlicher Kasuistiken statt. Den Fällen gemeinsam sind hoher Leidensdruck, geringe Neigung zur Spontanheilung sowie jahrelange schulmedizinische Vorbehandlung. Durch die homöopathische Therapie konnte in allen Fällen ein nicht mehr behandlungsbedürftiger Hautbefund erzielt werden.
Evidenz- und erfahrungsbasierte Phytotherapie bei Erkrankungen der Haut
Authors: Gündling Peter W. 
Published: October 2023

ZusammenfassungIm Gegensatz zu chemisch definierten Substanzen und Arzneimitteln sind Phytotherapeutika und Phytopharmaka Vielstoffgemische, die von der Natur über Jahrmillionen im Einklang mit ihrer Umwelt hervorgebracht wurden. Ihre Inhaltsstoffe dienen somit nicht nur dem Schutz und Gedeihen der Pflanzen selbst, sondern auch dem anderer Lebewesen und Lebensbereiche. Menschen und Tiere haben diese Eigenschaften schon früh wahrgenommen und seit Tausenden von Jahren genutzt. Wesentlicher Vorteil – bei richtiger Anwendung – dieser Vielstoffgemische ist ihre milde und breite Wirksamkeit und dadurch auch gute Verträglichkeit. Als Grenz- und Multifunktionsorgan bedarf die Haut – vielleicht mehr noch als andere Organe – einer ganzheitlichen Betrachtung. Somit sind bei deren Funktionsstörungen und Erkrankung alle Säulen der klassischen Naturheilverfahren von Bedeutung, insbesondere auch die Phytotherapie. Einige neuere und bewährte Erkenntnisse dazu werden nachfolgend anhand dreier klassischer Hautkrankheiten vorgestellt.