bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does minimally invasive anatomical hepatectomy reduce surgical site infections?
Authors: Maeda Tetsuya , Ito Yuko , Hosaka Hiroka , Yamazaki Seiko , Kajiwara Yoji , Onishi Ken , Okada Rei , Matsumoto Yu , Kimura Kazutaka , Ishii Jun , Tsuchiya Masaru , Otsuka Yuichiro 
Published: January 2025

Aim: This study aims to clarify the effectiveness of laparoscopic anatomical liver resections (ALRs) in surgical site infections (SSIs).
Methods: We included 95 cases (44.0%) of laparoscopic ALRs (LALRs) and 121 (56.0%) of open ALRs (OALRs). Retrospective comparisons were performed between the two groups.
Results: In preoperative factors, tumor size was significantly smaller in LALRs than in OALRs (34.4 ± 23.0 mm vs . 45.9 ± 35.7 mm, P = 0.007). The operative duration was longer in LALRs than in OALRs (523.0 ± 186.5 min vs . 356.3 ± 100.5 min, P < 0.001). However, the blood loss and the blood transfusion were fewer in LALRs than in OALRs (592.1 ± 911.7 mL vs . 1,240.6 ± 1,131.8 mL, P < 0.001, 26.3% vs . 48.8%, P = 0.001, respectively). Postoperative complications above the Clavien-Dindo grade IIIb were one case (1.1%) in LALRs and two in OALRs (P = 1.000). The postoperative hospital stay was shorter in LALRs than in OALRs (14.8 ± 16.5 days vs . 20.7 ± 18.9 days, P = 0.017). There was one (0.8%) postoperative death within 90 days in OALRs and none (0.0%) in LALRs (P = 1.000). Incisional SSIs (ISSIs) were significantly reduced in LALRs than in OALRs (1.1% vs . 7.4%, P = 0.045). Organ/space SSIs (OSSIs) were observed in five cases (5.3%) in LALRs and seven cases (5.8%) in OALRs (P = 1.000). A strong correlation between bile leakage and OSSIs was found. Although OSSIs (Odds ratio 31.200, P = 0.009) were the significant predictive factors for developing ISSIs in OALRs, no risk factors predicting ISSIs were found in LALRs using Multivariate logistic regression analyses.
Conclusion: Although this is a limited study at a single institution, minimally invasive anatomical hepatectomy can reduce ISSIs.
Quality of Life and Bank Investments of the Population in the Regions of the Russian Federation
Authors: Arshakyan R. A. , Kurbatsky A. N. , Mironenkova M. V. 
Published: January 2025

Improving the living standards of citizens and improving the investment climate are the key benchmarks of any state.The purpose of this study is to analyze the relationship between quality of life and the growth of bank deposits in the regions of Russia.Materials and methods. The integral index of the quality of life of the population of the Russian regions from 2011 to 2021 was assessed using the method of principal components based on blocks of variables reflecting not only material but also spiritual and moral spheres of society. The authors analyzed the presence of correlation between the integral index of the quality of life and the volume of bank deposits. Assuming that the integral index of the quality of life can have a significant impact on the growth of bank deposits, panel data models with fixed and random effects were constructed and analyzed. The data from the Federal State Statistics Service (Rosstat) and from open Russian Internet resources on banking analytics were used in the paper.Results. The paper shows that despite the presence of a stable correlation between the value of the integral index of the quality of life and the estimate of the volume of deposits, the quality of life does not have a significant impact on the growth of bank investments. Regional inflation is expected to have a negative impact on deposit growth.Conclusion. The increase in free cash stimulates the population to choose the most reliable ways of their preservation and multiplication, for example, bank deposits. However, improving the quality of their lives, the population may begin to consider other, albeit less reliable, but perhaps more profitable areas of investment, such as real estate or mutual funds. In addition, today the compensation for deposits in a bank, in respect of which an insured event has occurred, is paid to the depositor in the amount not exceeding 1.4 million rubles, which encourages agents to consider other investment instruments, if the available free cash exceeds the above amount. In conditions when the growth rates of consumer prices exceed the return on deposits, their real return becomes negative, which means that the population will look for alternative ways of investment. Analysis that takes into account different types of investment by regions of the country is currently a difficult task due to the aggregation and non-transparency of this type of data. We also note that the turbulent period starting from 2022, characterized by a sharp increase in interest rates, requires separate consideration.
Role of growth factors (transforming growth factor β1 and connective tissue growth factor) in the progression of diabetic retinopathy
Authors: Hudz A.S. , Kudryl I.V. 
Published: January 2025

Background. The study on the mechanisms of progression of diabetic retinopathy (DR) and growth factors that directly participate in this process is relevant, as it will allow substantia­ting a new possible direction of treatment and diagnosis. Aim is to establish the role of transforming growth factor β1 (TGF-β1) and connective tissue growth factor (CTGF) in the development and progression of DR. Materials and methods. The study involved the results of the examination of 102 people with type 2 diabetes mellitus who were divided into 3 groups according to the stages of DR: first one — non-proliferative DR (NPDR, 35 people), second one — pre-proliferative (PPDR, 34 people) and third one — proli­ferative (PDR, 33 people). The control group consisted of 61 individuals. The patients underwent standard ophthalmic examinations. TGF-β1 in serum and intraocular fluid (IOF) and CTGF in IOF were evaluated by enzyme-linked immunosorbent assay (Invitrogen Thermo Fisher Sci., USA). Statistical analysis of the results was performed using the MedCalc Software package (MedCalc Software bvba, 1993–2013). Results. The blood TGF-β1 content was increased in patients with DR by 1.4–1.55 times compared to controls (p < 0.001). The difference in terms of DR stages was not statistically significant. The TGF-β1 content in IOF increased significantly depending on DR stages and was higher in NPDR by 1.2 times, in PPDR by 2.2 times, and in PDR by 5.0 times (p < 0.001) compared to controls. At the same time, the difference between all groups was statistically significant (p < 0.05). The CTGF content in the IOF also increased significantly and was 1.6 times higher in NPDR, 2.2 times higher in PPDR, and 3.2 times higher in PDR compared to controls (p < 0.001). Comparison of TGF-β1 and CTGF levels in the IOF showed that an increase was characteristic of both markers, but it was more pronounced for TGF-β1 in PDR. Conclusions. In our study, we found a significant increase in TGF-β1 and CTGF content in the IOF, which corresponded to the stage of DR. This suggests that both cytokines may be biomarkers of DR and are potential targets of its therapy.
Prognostic model for improving the quality of vision after phacoemulsification
Authors: Zhaboyedov D.G. , Kochuhur I.V. 
Published: January 2025

Background. Phacoemulsification is one of the most common and effective methods of cataract surgery, which allows patients to restore their vision and improve quality of life. Given the significant variability in outcomes, there is a growing need to develop prognostic models that help predict the quality of vision after surgery. Such models consider clinical, demographic, and biometric data of patients, which allows doctors to personalize approach to treatment and optimize outcomes. However, even with such effective technologies, the result may not always meet the expectations of patients, as it depends on many factors. The purpose of the study was to create a prognostic model to determine the treatment algorithm for a patient with age-related cataract. Materials and methods. A study was conducted of 160 patients (160 eyes), 80 women and 80 men aged 45–75 years who were diagnosed with age-related cataract. They were divided into two groups: experimental one (80 patients) — initial visual acuity 0.8–1.0; control group (80 patients) — initial visual acuity < 0.8. The assessment was performed in two stages: 1 day before surgery and 1 month after surgery. MedStat and EZR programs were used for statistical processing. Results. To calculate the ROC curve of the multivariate model for visual quality improvement in patients after phacoemulsification, the following factors were taken into account: visual acuity, spherical aberrations, contrast sensitivity using the Pelly-Robson chart and the Clinic CSF Contrast Sensitivity test. According to the calculations, the AUC was found to be 0.89 (95% CI 0.79–0.99), which is statistically significantly (p < 0.05) different from 0.5 and is evidence of the model adequacy. Calculation of the model by the formula showed a better result in the experimental group (87.8 %) than in controls (76.2 %). Thus, with surgical intervention, the prognosis for improving the quality of vision is more favorable in the experimental group. Therefore, it is necessary to carry out surgeries at early stages, when the patient’s visual acuity is 0.8–1.0, in order to achieve the maximum quality of vision, unlike the control group. Conclusions. The proposed prognostic model for predicting the improvement of visual quality after phacoemulsification showed high accuracy and practical value. It was found that phacoemulsification with intraocular lens implantation in patients from the experimental group is more effective in achieving higher quality of vision than in controls. Thus, to achieve the best visual quality, surgical intervention should be performed at early stages.
Improving the technique of antiglaucomatous surgery by using absorbable suture material in patients with primary open-angle glaucoma
Authors: Zavgorodnia N.G. , Didenko L.G. 
Published: January 2025

Background. Surgical treatment of glaucoma is aimed at achieving target intraocular pressure and obtaining a sustained hypotensive effect. Fibrosis of the filtering bleb in the early and late postoperative period leads to the search for new techniques to improve surgeries. The purpose was to assess the effectiveness of an improved surgical technique using absorbable suture material in patients with primary open-angle glaucoma. Materials and methods. Work with patients was carried out in compliance with the general requirements and provisions of bioethics, which were approved by the First National Congress on Bioethics (Kyiv, 2001). Informed consent was obtained from each patient. Forty-nine individuals (47 eyes) with primary open-angle glaucoma took part in the study. The main group included 25 patients (27 eyes) with uncompensated open-angle glaucoma who underwent antiglaucomatous surgery using absorbable suture material. Control group consisted of 24 patients (20 eyes), in whom antiglaucomatous surgery was performed in a classical way without using of polyglycolide. Examinations were performed before surgery, each week after it for a month and then at 3, 6, 12, 18 and 24 weeks. In addition to standard methods, ophthalmic examination included tonography on an electronic Model 30 Pneumatonometr (Reichert, USA), control of the morphological state of the filtering bleb was carried out by computer tomography using DRI OCT Triton (Topcon, Japan) and Visante OCT (Carl Zeiss, Germany). Results. In the main group in the postoperative period, the intraocular pressure stabilized, its level did not exceed 22 mm Hg, while in the control group, there was an increase in the average indicator to 28.1 mm Hg six months after surgery. The coefficient of the outflow facility in the postoperative period in the main group was more stable and amounted to 0.26 ± 0.06 mm3/min/mm Hg, and in the control group, there was a decrease to 0.19 ± 0.08 mm3/min/mm Hg, which indicated destabilization of hydrodynamic processes. Conclusions. The technique of antiglaucomatous surgeries improved by using absorbable suture material is more effective in patients with primary open-angle glaucoma compared to classic antiglaucomatous surgery.
Risk of ineffective treatment for diabetic retinopathy of different stages and prognostic factors that determine it
Authors: Serdiuk A.V. , Mogilevskyy S.Yu. 
Published: January 2025

Background. The purpose was to study the effectiveness of diabetic retinopathy (DR) treatment with different methods and to establish prognostic indicators of its failure. Materials and me­thods. A total of 358 patients (358 eyes) with type 2 diabetes were examined and divided into groups: 1 — with non-proliferative DR (NPDR; 189 eyes), 2 — with preproliferative DR (PPDR; 96 eyes) and 3 — with proliferative DR (PDR; 73 eyes). The central retinal thickness and central retinal volume were determined by optical coherence tomography; serum fasting glucose, glycated hemoglobin, cholesterol, high-, low- and very-low-density lipoproteins, triglycerides, fibrinogen — by colorimetric method; coagulation hemostasis parameters were evaluated as well. Patients were followed for 2 years with conservative, laser, surgical treatment and anti-VEGF therapy. The study results were analyzed using the EZR v. 1.54 package (Austria). Results. Conservative treatment was effective in 54.5 % of patients with NPDR. In PPDR and PDR, 98.8 % of patients showed slow or rapid progression of retinopathy after treatment. The independent factors that determined the failure of treatment for NPDR were the patient’s age, diabetes duration, blood cholesterol and glycated hemoglobin levels, as well as activated plasma recalcification time and thrombin time. The independent factors that determined the ineffectiveness of treatment for PPDR and PDR were blood triglycerides, prothrombin time and activated partial thromboplastin time. Conclusions. Lipid metabolism disorders and coagulation homeostasis were powerful factors in the progression of DR and treatment failure. The ineffectiveness of NPDR treatment increased with age and duration of diabetes.
A novel two-stage and combined treatment of primary open-angle glaucoma and cataract: comparative efficacy and complications
Authors: Romaniuk A.V. 
Published: January 2025

Background. The approach to the treatment of patients with primary open-angle glaucoma and cataract is still a subject of debate, because when choosing a particular type of procedure, as well as determining the timing of its performance, it is necessary to consider a significant number of factors that may affect success of treatment. There are limited data on the outcomes of combined treatment of patients with primary open-angle glaucoma and complicated cataract, which includes phacoemulsification with intraocular lens (IOL) implantation and micropulse transscleral cyclophotocoagulation (MP-TSCPC). The purpose is to compare efficacy and to study the nature and frequency of complications when using novel, two-stage and combined surgical and laser methods for treating primary open-angle glaucoma with cataract. Materials and methods. The study includes 112 patients (112 eyes) with primary open-angle glaucoma stage I–IV and complicated cataract. There were 3 observation groups. In the first one (n = 34), phacoemulsification with IOL implantation was performed 1 month prior to MP-TSCPC. The second group (n = 36) included patients who underwent phacoemulsification with IOL implantation a month after MP-TSCPC. In the third group (n = 42), phacoemulsification with IOL implantation and MP-TSCPC were performed in one procedure. These groups did not statistically differ in terms of age, gender, baseline intraocular pressure, stage of primary open-angle glaucoma and nuclear lens density. The primary outcome measure was the normalization of intraocular pressure with or without the use of antiglaucoma medications and without need for repeated laser and incisional procedures after 1, 3 and 6 months. The secondary outcome measure was stabilization or expansion of visual fields 1, 3, and 6 months after treatment. The complication nature and rates were evaluated. Results. In the third group, where combined treatment was performed, the incidence of transient hypertension and inflammatory complications was statistically higher. There was a tendency to a higher incidence of corneal edema, cystoid macular edema, and hypotony as well; 7.1 % of patients required repeated MP-TSCPC, but this was statistically insignificant. According to the survival analysis, a statistically significant difference was found between the three groups in functional (p = 0.036) and hypotensive outcomes (p = 0.046), with the best result in the second group at 6 months of follow-up. Conclusions. The efficacy assessed by hypotensive and functional outcomes at a follow-up period of 6 months appeared to be statistically lower in the group of combined treatment compared to the groups in which two-stage treatment was conducted.
KONSEP JIZYAH DALAM PANDANGAN IBN RUSYD AL-QURṬUBĪ (Analisis Perspektif Siyāsah Māliyah)
Authors: Juliani  , Safira Mustaqilla  
Published: January 2025

Konsep jizyah dalam kajian hukum Islam termasuk dalam hukum pemerintahan, yaitu kewajiban kafir żimmi untuk mengeluarkan sebagian hartanya pada negara sebagai jaminan keamanan dan keselamatan. Para ulama masih belum padu dalam menetapkan hukum jizyah. Pada penelitian ini secara khusus membahas pendapatIbn Rusyd Al-Qurṭubī. Adapun permasalahan yang diajukan ialah bagaimanakah pandangan Ibn Rusyd Al-Qurṭubī tentang konsep jizyah, dan bagaimana tinjauan siyāsah māliyah terhadap pelaksanaan jizyah dilihat dari pandangan Ibn Rusyd Al-Qurṭubī? Penelitian ini menggunakan metode penelitian kualitatif, dengan jenis penelitian kepustakaan dan pendekatan normatif, data dikumpulkan melalui studi kepustakaan, kemudian dianalisis dengan menggunakan Deskriptif analisis. Hasil penelitian ini bahwa di dalam pandangan Ibn Rusyd Al-Qurṭubī, konsep jizyah termasuk perkara yang wajib dilaksanakan oleh pemerintah. Kewajiban jizyah diberlakukan pada orang kafir, baik ahl al-kitab (Yahudi dan Nasrani) dan musyrik (politeisme), termasuk kepada orang Majusi. Syarat-syaratnya adalah status mereka adalah kafir zimmi (ahlu żimmah), bukan kafir harbi, laki-laki yang merdeka dan baligh. Adapun jenis jizyah menurut Ibn Rusyd ada dua, yaitu jizyah ṣhulhiyyah dan jizyah ‘unwiyyah. Pelaksanaan jizyah menurut pandangan Ibn Rusyd Al-Qurṭubī sesuai dengan tinjauan siyāsah al-māliyah. Kebijakan pemerintah yang mewajibkan kafir żimmi mengeluarkan jizyah adalah bagian dari jenis kebijakan yang sifatnya politis menyangkut harta (maliyah), harta jizyah menjadi khas negara untuk kepentingan kemaslahatan rakyat, baik muslim maupun non-Muslim (kafir).
Impact of physical climate risks on agricultural firms’ bankruptcy: evidence from France, Italy, Portugal and Spain from 2016 to 2019
Authors: Pastor-Sanz Ivan , Tascón María T. , Castro Paula , Amor-Tapia Borja 
Published: January 2025

Abstract
Frequent and long-lasting extreme climate events can impact business-related natural capital, severely affecting production and resulting in losses for agricultural firms. Physical climate effects are material dependencies for agricultural businesses and may severely affect their performance and compromise their survival. This study’s aim is to analyze the comprehensive effect of climate change factors on agricultural firm bankruptcies in a European geographical area that is especially susceptible to climate change. Employing a panel of 15 036 agricultural firms, we analyze the effects of adverse climatic conditions in the firm’s headquarters area using logit regressions, an instrumental variable ordinary least squares model, and the gradient-boosting ensemble method. We find that bankruptcy is conditioned upon extreme weather events, indicating that climate change’s physical impacts on firm resources already materially affect the agricultural sector’s resilience and survival. Specifically, abnormally high temperatures, precipitation, and the incidence of fires are significant factors that contribute to bankruptcy or insolvency. Furthermore, a “fire weather” index comprising high temperatures, drought, and wind, combined with fire occurrence, intensifies the bankruptcy risk of agricultural businesses.
Effectiveness of Organic Fertilizer Enriched with Humic Acid on Soil Chemical Quality, Nutrient Uptake, and Shallot Yield in Calcareous Soils
Authors: Matheus Rupa , Kantur Donatus 
Published: January 2025

Calcareous soils have great potential for the development of food crops and horticulture, but they are constrained by high pH, low organic matter content, and less than optimal cation exchange capacity, thus affecting the availability of nutrients. This study aims to evaluate the effectiveness of organic fertilizer enriched with humic acid on soil chemical quality, nutrient uptake, and yield of shallots on calcareous soils. The study was designed with two factors, namely type of organic fertilizer (manure and bokashi) and concentration of humic acid (0%, 10%, and 20%) added to the organic fertilizer. The results of the study showed that the application of organic fertilizers, both manure and bokasih, had a similar effect on soil quality and shallot yields. However, the addition of humic acid at a concentration of 20% significantly improved the chemical properties of the soil, nutrient uptake (especially nitrogen and potassium), as well as the yield component of shallots when compared to the concentration of 10% and control. The addition of humic acid has been proven to be effective in improving nutrient availability and supporting plant growth. This innovation can be an effective solution to improve the quality of calcareous soils and agricultural products, especially shallots, which supports sustainable and environmentally friendly agriculture. Keywords: Calcareous soil, Humic acid, Nutrient uptake, Organic fertilizer, Shallots.
Resolução 2.173/2017: análise do impacto no diagnóstico de morte encefálica
Authors: Rulim Isabelita de Luna Batista , Moretti Miguel Antônio , Santos Antonia Thamara Ferreira dos , Rulim Marco Antonio Bezerra , Rulim Ana Laís Lacerda , Chagas Antonio Carlos Palandri 
Published: January 2025

Objetivo: Analisar o impacto da resolução 2.173/2017 do Conselho Federal de Medicina no diagnóstico de morte encefálica e no tempo de diagnóstico. Métodos: Estudo descritivo, com abordagem quantitativa. Amostra obtida a partir da análise retrospectiva dos prontuários de pacientes com diagnóstico clínico de morte encefálica nos anos de 2017 e 2018, 31 em cada ano, período antecessor e sucessor a mudança da lei que define os critérios de morte encefálica. Resultados: Dos 62 prontuários avaliados, 76% pertenciam a pacientes do sexo masculino; com a idade média de 40 anos. 52% pertenciam a Unidade de Terapia Intensiva. Das entrevistas realizadas para doação de órgãos, o procedimento foi negado em 52%. Houve um aumento no número de doações em relação aos anos avaliados, 7 em 2017 e 12 em 2018. Observou-se uma redução no tempo das avaliações clínicas e um aumento no número dos profissionais aptos a fazer as avaliações de morte encefálica. Conclusão: A resolução está diretamente ligada a celeridade no processo de diagnóstico de morte encefálica, com impacto na redução do tempo de confirmação do diagnóstico, no aumento do número dos profissionais habilitados e aumento no número de doações de órgãos.