bluuebunny/crossref_metadata_2025_split huggingface dataset:
Remission of Cushing's syndrome during pregnancy
Authors: Margulies Paul L. , Imperato‐McGinley Julianne , Arthur Ann , Peterson Ralph E. 
Published: April 2004

AbstractWe present the first report of pregnancy with Cushing's syndrome due to an adrenal cortical adenoma, in which the hypercortisolemia disappeared during the third trimester of pregnancy, but recurred following the delivery of a normal male infant at 38 weeks by Cesarean section. The case is also unique because plasma ACTH levels were elevated during gestation and postpartum. Also, urinary estriol excretion was very low during the third trimester of pregnancy. The relationship of Cushing's syndrome and pregnancy are reviewed. This study points up some of the limitations of the routinely used dynamic tests of pituitary‐adrenal function in Cushing's syndrome, and emphasizes the importance of various radiologic procedures in evaluation of patients with Cushing's syndrome.
Trends in perinatal mortality at a Hong Kong hospital
Authors: Woo Joseph S.K. , Chan Pak‐Hang , Wong Vivian C.W. , Ma Ho‐Kei 
Published: April 2004

AbstractCauses of perinatal mortality at Tsan Yuk Hospital, Hong Kong, were classified into 14 categories from the “P” list of stillbirths and neonatal mortality in the International Statistical Classification of Diseases, Injuries and Causes of Death. Trends for each category over the period 1970–1979 were examined by regression analysis. Overall perinatal mortality fell from 17.80 in 1970 to 10.94 in 1979. A low incidence of deaths from congenital abnormality and medical complication in the mother was observed. Significant statistical correlations were obtained in the trends in mortality associated with placental hemorrhage, pre‐eclampsia, difficult labor, hemolytic disease of the newborn, and prematurity. Improvements in perinatal mortality in these areas as well as inadequacies in perinatal care in other areas, are discussed.
Effect of ethyl alcohol infusions on glucose and hormone status in ovine pregnancy
Authors: Cook P.S. , Head H.H. , Notelovitz M. , Abrams R.M. 
Published: April 2004

AbstractTerm pregnant ewes were given ethanol in dextrose water i.v. according to the usual 2‐h loading dose recommended for premature labor. Glucose, insulin, cortisol, progestins, estrone and estradiol in maternal and fetal plasma were measured for 5 h. In both treated animals and controls (dextrose water only) there was a reduction in maternal cortisol and a reduction followed by a rise in progesterone concentration. Mean concentration of insulin in maternal plasma across all sampling times was higher in ethanol treated animals.
Langerhans cells in human papillomavirus (HPV) lesions of the uterine cervix identified by the monoclonal antibody OKT‐6
Authors: Väyrynen M. , Syrjänen K. , Mäntyjärvi R. , Castrén O. , Saarikoski S. 
Published: April 2004

AbstractThe local inflammatory cell infiltrates in 263 cervical punch biopsies of the women followed‐up since 1981 (16 ± 14 months, mean ± S.D.) for an established human papillomavirus (HPV) lesion with or without concomitant cervical intraepithelial neoplasia (CIN) were analysed for occurrence of Langerhans cells, defined by the monoclonal antibody OKT‐6 using the avidin‐biotin peroxidase complex (ABC) technique, OKT‐6+ cells remained at the constant low level (1.5–1.9% of the inflammatory cells) in the different types of HPV lesions (flat, inverted or papillomatous condylomas), their percentages (range 0.8–2.1% of the cells) being slightly affected by the grade of HPV‐associated CIN, however (P < 0.05 between HPV‐CIN I and HPV‐CIS). Although cervical HPV lesions characteristically are a disease of young females, the relative levels of in situ Langerhans cells did not show any age‐dependence. Furthermore, the intensity of the inflammatory cell infiltrate did not correlate with the relative levels of OKT‐6+ cells in the biopsies. Practically identical (1.6%) levels of OKT‐6+ cells were found in the first biopsies of the HPV lesions shown to regress during the follow‐up period (28.8% of cases), when compared with those (1.7%) in the lesions persisted (52.1% of cases) or progressed (19.1% of lesions). The results are discussed in terms of the proposed immune surveillance function against viral infections, attributed to Langerhans cells in the SALT/MALT concept. The results confirm the presence of Langerhans cells as integral constituents of the local immunocompetent cell infiltrates in uterine cervix, and as such they may well contribute to the regulation of the clinical course of HPV lesions by the in situ immune reactions.
Postcoital recovery of sperm in Douglas pouch aspirates of infertile patients
Authors: Aref I. , Reda M. , Kandil O. , El Tagi A. 
Published: April 2004

AbstractTubal dysfunction is certainly involved in some cases of infertility. Clinical diagnostic procedures for tubal patency are occasionally misleading and contradictory. Moreover, they provide no information on tubal function. The recovery of viable sperm in Douglas pouch aspirates (DPA) was used to evaluate tubal function in 94 infertile patients with different tubal findings at hysterosalpingography (HS) and laparoscopy. Sperm recovery in DPA of ten infertile patients with poor or negative postcoital Sims‐Huhner test results demonstrated the limitation of this test for evaluation of sperm transport in the female genital tract. Laparoscopic aspiration of DP may be performed in infertile patients under‐going chromosalpingoscopy as a part of their infertility investigation. The procedure should be supplementary to other available diagnostic parameters.
Vaginal versus cesarean section oriented approaches in the management of breech delivery
Authors: Confino Edmond , Ismajovich Bernardo , Sherzer Anat , Peyser Reuben M. , David Menachem P. 
Published: April 2004

AbstractIn a 5‐year retrospective study, 543 singleton breech presented infants weighing more than 1000 g were reviewed in two obstetric departments. Department “A” actively conducted the labor with lower cesarean section rate (26%). Department “B” attempted a trial of labor with less invasive procedures and performed more cesarean sections (38% P < 0.05 S). The management of labor, fetal and maternal outcome were compared between the two departments. Both vaginal and abdominal routes of delivery in fetuses weighing more than 1500 g resulted in the same fetal and maternal outcome. For fetuses weighing 1000–1500 g cesarean section is probably the recommended delivery route.
Plasma arginine vasopressin response to water load during labor
Authors: Singhi Sunit , Parshad Omkar 
Published: April 2004

AbstractTo find out whether plasma vasopressin (PAVP) response to a water load during pregnancy is inappropriately high, as had been speculated, we measured PAVP by radioimmunoassay in 30 women at the time of delivery. Ten women had received infusion of aqueous glucose solution during labor for hydration (GW group); another ten received infusion of glucose solution as a vehicle for oxytocin (OT group), and ten women did not receive any intrapartum intravenous fluid therapy (controls). Serum sodium and osmolality were also determined in all the subjects. PAVP levels were significantly lower in GW (0.70 ± 0.4 pg/ml) and OT groups (0.7 ± 0.6 pg/ml) (P < 0.05). Significant negative correlation was seen between the amount of glucose solution infused and levels of PAVP (r = −0.66; P < 0.01), while a significant positive correlation was seen between PAVP and serum sodium (r = 0.61; P < 0.01). These findings suggest that during labor, the physiological relationship between serum osmolality and PAVP is intact, and that infusion of a water load in the form of aqueous glucose solution is attended by an expected lowering of PAVP. We infer that inappropriate ADH response is not the cause of water retention and hyponatremia often seen in women receiving aqueous glucose solution during labor.
Ectopic pregnancy in a distal tubal remnant
Authors: Molloy B.G. , Beck I. , Glass M.R. 
Published: April 2004

AbstractEctopic pregnancy is a well‐recognized complication of tubal reanastomosis (Young PE, Egan JE, Barlow JJ: Reconstructive surgery for infertility at the Boston Hospital for Women. Am J Obstet Gynecol 108: 1092. 1970 and Hodari AA, Vibhasiri A, Isaac AY: Reconstructive tubal surgery for midtubal obstruction. Fertil Steril 28: 620, 1977). We describe here, however, a case of tubal pregnancy occurring in a tubal remnant on the opposite side to a successful tubocornual reanastomosis.
Congenital adrenal hyperlasia and luteal dysfunction
Authors: Villanueva A.L. , Rebar R.W. 
Published: April 2004

AbstractA case of 21‐hydroxylase deficiency diagnosed and first treated at the age of 3 years is presented. Although pubertal development was delayed, full reproductive function was attained, with menses occurring at 14–33‐day intervals. Infertility evaluation at age 20 revealed elevated 17‐hydroxyprogesterone (17Po) and androgen concentrations and reduced luteal phase progesterone levels consistent with inadequate luteal function. This was corrected with additional cortico‐steroid replacement. Normal pregnancy and delivery followed.
The accuracy of hysterosalpingography versus laparoscopy in evaluation of infertile women
Authors: Ismajovich Bernardo , Wexler Shraga , Golan Abraham , Langer Lea , David Menachem P. 
Published: April 2004

AbstractTwo hundred fifteen infertile women underwent hysterosalpingography (HSG) and laparoscopy. One hundred twenty‐eight patients had bilaterally patent tubes on hysterosalpingography. Thirty‐one percent of these women had pelvic adhesions diagnosed by laparoscopy. Eighty‐seven women had either occluded tubes or suspected pelvic adhesions on hysterosalpingography. Thirty‐nine percent of these women had patent tubes without any pelvic pathology on laparoscopy. Inaccurate diagnoses limit the value of hysterosalpingography in evaluation of tubal and peritubal pathology.
Chlamydia trachomatis: A practical obstetric/gynecologic management approach
Authors: Meriwether C.D. , Evans M.I. , Sokol R.J. 
Published: April 2004

AbstractChlamydia trachomatis has assumed a critically important role in the pathogenesis of gynecologic/perinata/neonatal infectious morbibidity. C. trachomatis is responsible for several infectious syndromes in the non‐pregnant woman, the mother and her offspring. Detection and treatment of chlamydia infections are as important as that of other sexually transmitted diseases (STDs) such as GC, syphilis, trichomoniasis, etc. An appreciation of the seriousness of the resulting disorders and a high index of suspicion are absolute prerequisites for successful management.
Congenital adrenal hyperplasia: The surgical treatment of vaginal stenosis
Authors: Rock J.A. , Schlaff W.D. 
Published: April 2004

AbstractTen postpubertal women with congenital adrenal hyperplasia (CAH) had significant vaginal stenosis after at least one previous attempt at vaginal reconstruction. Two women had had two unsuccessful surgical attempts to obtain a vagina of adequate size to allow sexual relations. This report describes a surgical procedure to exteriorize the vagina. With post‐operative vaginal dilatation and proper patient counseling, this combined approach has resulted in a vagina of adequate size to allow comfortable intercourse.
Non‐vascular transplantation of the rabbit uterus
Authors: Confino E. , Vermesh M. , Thomas W. , Gleicher N. 
Published: April 2004

AbstractTransplantation of the uterus may be an optimal solution in young hysterectomized patients, in women with agenesis of the uterus or in severe uterine anomalies. In the human model, attempted tubal and ovarian homografts have usually failed. Eighteen rabbits underwent unilateral non‐vascular uterine transplantation. Four rabbits underwent total unilateral uterine autograft. Three uteri showed severe inflammation and necrosis 72, 1 week and 1 month postoperatively. Thereafter, the operative technique was modified to avoid contamination from the vagina and four rabbits underwent supravaginal unilateral non‐vascular autograft. Three uteri had preserved endometrial and myometrial structure on relaparotomy. The following four rabbits underwent homotransplantation of the uterus and showed acute rejection of the transplant. Under cyclosporine therapy three homotransplanted rabbits developed pelvic abscesses while three other rabbits showed preserved myometrial and endometrial structures.
Determination of trace and bulk elements in plasma and erythrocytes of diabetic pregnant women by pixe method
Authors: Gödény Sándor , Borbély‐Kiss Ildikó , Koltay Ede , László Sándor , Szabó Gyula 
Published: April 2004

AbstractProton‐Induced X‐ray Emission (PIXE) analysis of blood samples from diabetic pregnant women was carried out. Elements S, Ca, P, K, Cl, Fe, Zn, Cu, Rb and Br were detected in red blood cells, while S, Ca, P, K, Cl, Fe, Zn, Cu, Ni, Br in the plasma. The concentrations of P, S, Ni, Cu were found to be higher, while those of K, Fe, and Zn were lower in diabetic plasma than in controls. Significantly higher concentrations were measured for P, S, Cl, Fe, Zn and Rb in diabetic erythrocytes compared to normals. Statistical evaluation of the results also indicated significant alteration in the changes of concentrations throughout the pregnancy. Diabetes also resulted in changes in most of the correlations observed in normal pregnancy between the concentrations of elements.
Rapid regression through bromocriptine therapy of a suprasellar extending prolactinoma during pregnancy
Authors: Tan Seang Lin , Jacobs Howard S. 
Published: April 2004

AbstractA 29‐year‐old woman is described who presented with amennorrhea and galactorrhea with a large prolactinoma which regressed on bromocriptine therapy. Treatment with bromocriptine was stopped when pregnancy was diagnosed but 6 weeks later the prolactinoma had regrown with suprasellar extension and lateral invasion of the cavernous sinus. When treatment with bromocriptine was reinstituted symptoms subsided within 24 h and serum prolactin concentrations fell from 54,000 mM/l to 2800 mU/l within 5 days and 500 mU/l 2 days after that. Pregnancy proceeded without complications and she entered spontaneous labor at term and delivered a healthy baby. One year after delivery, on treatment with bromocriptine, her serum prolactin concentration remains within the normal range and the CT scan shows persistence of a small prolactinoma, confined to the pituitary fossa. Bromocriptine should be the primary treatment for prolactinomas regardless of tumor size and may be safely stopped when pregnancy is desired. If pituitary tumor complications occur during pregnancy, reintroduction of treatment with bromocriptine should again be the treatment of choice.
Time to conception after IUD removal: Importance of duration of use, IUD type, pelvic inflammatory disease and age
Authors: Andolsek Lidja , Teeter Rebecca A. , Kozuh‐Novak Mateja , Wheeler Robert , Fortney Judith A. , Rosenberg Michael J. 
Published: April 2004

AbstractSome investigations of IUD use have demonstrated impaired ability to become pregnant after removal, while others have not. None of these studies, however, have adequately considered such potentially influencing variables as age and a history of pelvic inflammatory disease (PID). To study the effect of length of IUD use, IUD type and the modifying influences of age and PID history on time required to conceive, we followed women trying to become pregnant after removal of their IUD. Five hundred forty women in Ljubljana, Yugoslavia who were first fitted with an IUD between 1964 and 1972 and had their IUD removed in order to become pregnant were followed through 1980. We found no relationship between the duration of IUD use or type of IUD used, but increasing age and a history of PID each decreased the montly probability of conception. These findings, along with other recent work, indicate that IUDs are a safe and efficacious contraceptive for women at low risk for sexually transmitted diseases.
Twin birth weight discordancy in Nigeria
Authors: Fakeye Olurotimi 
Published: April 2004

AbstractThe perinatal outcomes for 56 birth‐weight discordant twin pairs among 622 total twin deliveries that occurred over an 18‐month period at the University of Ilorin Teaching Hospital are analyzed. The incidence of twin birth‐size discordancy was 9%. Mean birth‐weight (kg) was 2.78 ± 0.5 for the heavier twin and 1.90 ± 0.5 for the smaller twin, with a mean intra‐pair birth‐weight difference of 0.88 kg (31.7% of the heavier twin). Perinatal mortality in the smaller infants was increased above the mean for all twin births. There were no perinatal deaths among the heavier infants. Discordant twinning was associated with high parity and a disproportionate increase of unlike‐sex pairs. These observations suggest the preponderance of discordancy in dizygotic twinning. Increased awareness and surveillance for discrepant twin pairs are suggested in order to improve perinatal outcome.
Ovarian function immediately after the menarche
Authors: Borsos A. , Lampé L.G. , Balogh A. , Csoknyay J. , Ditroi F. 
Published: April 2004

AbstractEstrone and pregnanediol‐glucuronide values of early morning urine samples collected from young girls in the perimenarche were determined by radioimmunological technique. A total of 58 teenage girls started collecting urine samples after their menarche at various times. Of these, 9 completed collection within 100 days of the onset of the first menstrual period. In 3 cases, insignificant changes in estrone and pregnanediol levels were noted. Normal estrone values were found in 3 cases together with pregnanediol levels suggestive of ovulation. In 2 further cases the possibility of ovulation without follicular release was suggested. The results indicate that ovarian activity is unpredictable immediately following the menarche. Between very low levels of sexual steroid hormone production and those normally observed in adult females, all transitional values could be found.
Peridural morphine analgesia by means of a subcutaneously tunnelled cannula
Authors: Hamar O. , Csömör S. , Kazy Z. , Vigváry Z. 
Published: April 2004

AbstractPeridural morphine analgesia is a well tested method of pain relief for patients with gynecological tumors which are in an advanced stage. Traditional methods of fixation can slightly inconvenience the patient when cleaning and dressing procedures are being carried out, and the cannula can be displaced or damaged.Fifty patients were treated with subcutaneously tunnelled peridural cannula. The procedure and its favorable results are described.
Antenatal iron supplementation in sickle cell disease
Authors: Akinyanju O.O. , Nnatu S.N.N. , Ogedengbe O.K. 
Published: April 2004

AbstractFourteen pregnant women with sickle cell disease (11 SS and 3 SC) were randomized into two groups to receive routine antenatal supplementation either with ferrous gluconate or with placebo tablets. Their hemoglobin levels and bone marrow iron content were determined prenatally and 6 weeks post partum. The fetal weights and the incidence of pain crisis in both groups were recorded. Using an iron content grading from 0 to 5, no marrow of any subject showed iron depletion. The placebo group showed an aggregate postnatal loss of 4 grades of iron repletion while the iron supplemented group showed an aggregate gain of 2 grades. There were no significant differences between the birth weight or the incidence of pain crises in both groups.We conclude that routine iron supplementation is not justified in pregnant women with sickle cell disease, as it would tend to increase already adequate or excessive iron body stores. We recommend that a clear need for iron should be established before iron supplementation is prescribed to them.
Childbirth following primary cesarean section — evaluation of a scoring system
Authors: Dhall K. , Mittal S.C. , Grover V. , Dhall G.I. 
Published: April 2004

AbstractOf 1184 cases with previous cesarean section, 590 were selected for trial of vaginal delivery and 594 for repeat cesarean section. Of the former group, 76.6% had successful vaginal delivery. Incidence of uterine wound dehiscence and of perinatal mortality was highest in cases with primary classical cesarean section. Factors like indications for previous cesarean section, history of intercurrent vaginal delivery, weight of baby and period of gestation had positive correlation with delivery outcome.
Factors associated with clinical reactions to rubella vaccination in women
Authors: Nakazono N. , Fujimoto S. , Wakisaka A. , Ishii K. , Ichinoe K. , Aizawa M. 
Published: April 2004

AbstractTwo types of rubella vaccine were given to 272 seronegative healthy Japanese adult women. Clinical and laboratory studies on clinical reaction after vaccination were carried out on HI antibody response, HLA types, basal body temperature (BBT), menstrual cycles and serum progesterone levels of vaccinees. Clinical reactions were not associated with HLA types of vaccinees, but arthropathy occured significantly more often in women vaccinated at the progestational stage than in women vaccinated at the estrogenic stage.
The correlation of serum estrogens and androgens with bone density in the late postmenopause
Authors: Deutsch S. , Benjamin F. , Seltzer V. , Tafreshi M. , Kocheril G. , Frank A. 
Published: April 2004

AbstractA pilot group of 16 women in the late postmenopause were evaluated for bone density by computerized axial tomography (CT) scanning and for hormonal milieu. A highly statistically significant positive correlation between lumbar‐3 spongiosum density and both dehydroepiandrosterone‐sulfate (DHEA‐S), r = 0.67; P < 0.005 and androstenedione (A), r = 0.56; P < 0.03 was found. No such correlations were observed with estradiol (E2), estrone (E1) or an array of other hormones. The results of this preliminary report indicate a clear association of weak androgens with bone density in the late postmenopause.
Effect of mode of delivery on incidence of respiratory distress syndrome
Authors: Curet L.B. , Zachman R.D. , Rao A.V. , Poole W.K. , Morrison J. , Burkett G. 
Published: April 2004

AbstractThe effect of route of delivery on incidence of respiratory distress syndrome (RDS) has been controversial. While some investigators have reported no difference in RDS rates in infants born by cesarean section as compared to vaginal delivery, others have shown a significant increase in risk for RDS among infants born by cesarean section. Data from the 297 patients comprising the placebo group in the recently completed collaborative study of antenatal steroid therapy in the prevention of neonatal RDS, were analyzed to determine the effect of mode of delivery on RDS. The results indicate that infants born by cesarean section without labor have a higher risk for neonatal RDS than infants born vaginally or by cesarean section after a trial of labor.