bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical characteristics and prognosis of pediatric
Listeria monocytogenes
meningitis based on 10-year data from a large children’s hospital in China
Authors: Xia Xueqian , Zhang Lingyu , Zheng Hao , Peng Xiaoling , Jiang Li , Hu Yue 
Published: January 2024

ABSTRACT

This study aims to summarize the clinical characteristics and prognosis of
Listeria monocytogenes
(LM) meningitis in children in Chongqing, China. A retrospective analysis of the clinical data and follow-up results of 20 LM meningitis patients admitted to the Children’s Hospital of Chongqing Medical University (CHCMU) from January 2012 to December 2022 was performed. The LM meningitis incidence rate was between 0 and 14.3 per 100,000 persons. The median age at onset was 8.98 months. There were five neonate cases, which all had perinatal abnormalities. Seven non-neonatal cases (7/15, 46.7%) had a documented history of contaminated food intake. One case had primary immunodeficiency. The most common symptoms were fever (20/20), altered consciousness (19/20), and vomiting (15/20). Seven cases had seizures, eight cases had cranial nerve involvement, eight cases had positive Babinski sign, and 10 cases had positive meningeal signs. The most common complications were hyponatremia (6/20), hypokalemia (6/20), respiratory failure (5/20), subdural effusion (3/20), and hydrocephalus (2/20). Treatment primarily involved monotherapy or combination therapy with meropenem (15/20) and ampicillin (10/20). Fifteen cases were treated with monotherapy or combination therapy using vancomycin. Twelve cases were successfully followed up from 10 months to 9 years and 6 months, and all had favorable long-term outcomes. LM meningitis incidence in children is low and with nonspecific clinical manifestations. Strengthening food hygiene and safety education, and avoiding infections during pregnancy are important to prevent LM infection in neonates and high-risk individuals. Meropenem and ampicillin are the preferred treatments. Early diagnosis and treatment can improve prognosis.

IMPORTANCE
The incidence of LM meningitis is extremely low, and there is currently no standardized treatment. We conducted a retrospective analysis of ten years of data from CHCMU regarding diagnosed LM meningitis cases, aiming to provide clinical evidence for the diagnosis and treatment.
Comprehensive scrutinization of ternary hybrid Casson nanofluid flow in a conducting porous rotating disk with internal heating
Authors: Kumar Maddina Dinesh , Suneetha Sangapatnam , Ramasekhar Gunisetty , Ramesha M. , Raju C. S. K , Raju S. V. Sivarama 
Published: January 2024

The utilization of a ternary hybrid nanofluid, a recent development in the realm of nanofluids, can result in improved heat transfer. In the ongoing study, a ternary hybrid nanofluid flow is utilized, and it is carried out atop a porous spinning disc, which is exposed to a magnetic field, heat generation, thermal radiation, and Casson fluid. In this study, Blood/Water are taken as base fluids and (Ag–Au–Al2O3) are considered as a ternary hybrid nanoparticle. Nanoparticles made of gold and silver are put to use in a vast number of industries and fields, including nanotechnology and medicine. As a result of surface effects and quantum effects, these precious metals exhibit unique features in nanoform that play a vital role in with optical, magnetic, chemical, and mechanical behavior. Al2O3 unique optical, physical and biochemical qualities make it worthwhile for numerous uses, including nanophotonic, catalysis and the fabrication of high-energy composites. A set of relevant similarity transformations is used to generate non-dimensional forms of controlling paired nonlinear Partial Differential Equations (PDEs). MATLAB is used to perform a numerical solution with ODE45. In addition, the velocity outline decreases, and the temperature profile increases slightly before decreasing over a revolving disk when the values of magnetic parameters are increased. The distribution and radiant heat components heat up as the level gets higher. Aim and objectives of the study: The aim of this study is to analyze the Comprehensive Scrutinization of Ternary hybrid and Casson flow in a conducting porous rotating disk with internal heating. The primary objective of this analysis is to increase awareness of the impending energy crisis among those working in the industrial and technological sectors. Ternary nanoparticles (NPs) have a wide range of applications, which lends credence to the developed model. For example, Al2O3 can be used in a variety of ways that benefit society, it is used in water purification to remove water from the gas streams and extend people’s lives.
Landscapes as Multispecies Matters: the Mushing Landscape in the Making in Finnish Lapland
Authors: Äijälä Mikko 
Published: January 2024

Abstract
Animals are important players in tourism but their presence and agency in the formation of tourist landscapes has been largely disregarded. Landscapes are often considered to be unchanging material surfaces shaped through culture, thus leaving only a limited role for animals. Drawing on non-representational ideas of landscape, I focus on the (re)formation of a local tourist landscape that takes place in the unfolding atmospheric practices of mushing. I present two narratives that are based on mobile video ethnographic vignettes and accompanying short video clips to reflect on the role of the sled dogs in the making of the local mushing landscape. Finally, I develop the argument that nonhuman animals are a unique part of the fabric and sociality of landscapes, thus making landscapes unavoidably multispecies matters.
Measuring the Academic Aspects of Religious Literacy of Estonian Basic School Graduates
Authors: Sooniste Aleksandra 
Published: January 2024

Abstract
This paper reports on two domains of a survey to map the religious literacy of Estonian basic school graduates undertaken in 2022 to understand how well the respondents distinguish religion as a discursive category and how much they know about basic concepts of world religions and the Estonian religious landscape. The sample consisted of 392 respondents from schools all over Estonia, both from large urban and small rural schools. The survey was conducted with an original instrument designed according to the Estonian religious landscape, the content of the National Curriculum for basic schools, the educational model of religious literacy according to Francis and Dinham, and the characterization of religious literacy by Moore, Prothero, Francis and Dinham. The results reflect the reality of the Estonian situation. Being one of the least religious countries in the world and with almost no education about religions and worldviews in public education, the students do not have enough competencies in the examined areas to operate well in a religiously diverse world.
Children Born of War: The Recognition of Children Born of War as Victims in the Ongwen Case
Authors: Frisso Giovanna M 
Published: January 2024

Abstract
This article explores the challenges associated with recognizing children born of war as victims within the framework of international criminal law. Focusing on the case of Dominic Ongwen, a former child soldier and senior commander of the Lord’s Resistance Army (lra), it analyses how the criteria established in the definition of victim in the Rules of Procedure and Evidence of the International Criminal Court have been applied to children born of war. This analysis brings to the fore conceptual challenges to the recognition of children born of war as victims and highlights the risks that the binary victim-perpetrator that characterises the international criminal narrative presents to a comprehensive understanding of the experiences and needs of these children.
Constitutional Review as a Democratic Instrument
Authors: Kovács Kriszta , Tóth Gábor Attila 
Published: January 2024

Abstract
The article situates Rosalind Dixon’s Responsive Judicial Review in constitutional legal literature and engages with its central message by introducing the idea of constitutional courts as accessible democratic institutions. It compares constitutional review in a well-functioning and a declining democracy. After considering the relationship between democratic self-government and constitutional review, the article argues that a lawfully established, accessible, yet reasonably self-restraining constitutional court with the power of procedural and substantive review can be understood as a democratic institution. To support this claim, the article offers the example of Hungary, where democratization coincided with the birth of accessible constitutional review and where the decay of democracy has been accompanied by the decline of constitutional review. It concludes that constitutional justices can always have a choice. They can contribute to an autocratic transformation or resist the autocratic government by performing a Herculean task.
What Kind of Judicial Review for a Small, Post-Communist European Constitutional Democracy?
Authors: Bardutzky Samo 
Published: January 2024

Abstract
The proposal for a new approach to judicial review in Rosalind Dixon’s book Responsive Judicial Review: Democracy and Dysfunction in the Modern Age builds on the ideas of John Hart Ely presented in his seminal work Democracy and Distrust. The purpose of this article is to engage with the idea of the responsive approach to judicial review being embraced by the Slovenian constitutional court. The article purports to contribute to a larger effort – to a comparative and sociologically informed discussion on judicial review in different jurisdictions that aims to predict the potential of responsive judicial review in Central and Eastern European courts.
Enhancing the nutritional value of bread by the addition of insect powder: a novel class of food protein additives
Authors: Guan Q.H. , Qian S. , Chen L. , Feng X.C. 
Published: January 2024

Abstract
The shortage of protein resources has become an urgent issue, and insects have been identified as a promising source of animal protein. The present study aimed to investigate the potential of insect powder as a novel class of food protein additives in bread. In this study, three species of insect powder were compared to traditional protein sources to conduct a preliminary analysis of their nutritional value. These insect powders were then added to flour and baked to produce a high-protein bread. The results indicated that the insects used in this experiment were rich in protein and amino acids. Additionally, insect proteins extracted via the alkali extraction method exhibited a lower molecular weight than common proteins. The addition of insect powder did not affect the rheological properties of the bread but increased the protein content of the product while giving the bread a darker colour and a unique insect flavour.
Vacuum assisted and gravitational venous drainage in aortic valve surgery: A propensity-match study
Authors: Silvano Raffaele , Malvindi Pietro Giorgio , Mazzocca Francesca , Genova Stefania , Di Campli Emanuele , Paterna Francesca , D’Este Jacopo M. , Alfonsi Jacopo , Berretta Paolo , Munch Christopher , Di Eusanio Marco 
Published: January 2024

Introduction Vacuum assisted venous drainage (VAVD) is widely adopted in minimally invasive cardiac surgery. VAVD enables the advantage of using smaller cannulae in a reduced surgical field while allowing satisfactory drainage and pump flow. The production of gaseous micro-emboli is a recognized risk associated with VAVD, however no difference in clinical endpoints have been reported between patients operated on with gravity venous drainage (GVD) or with VAVD. Due to the paucity of data on selected surgical populations, we sought to evaluate the early outcomes of patients undergoing isolated aortic valve replacement using VAVD or GVD. Methods Data on 521 patients between 09/2016 and 09/2022 were retrieved from our internal database. Patients were divided into two groups according to use VAVD or GVD. A propensity match analysis was performed to account for difference between the two groups. Results The propensity match provided two well balanced cohorts with 129 patients each. A minimally invasive access was used in 97% of the cases in VAVD group vs 98% in GVD group ( p = .68). Mean cardiopulmonary by-pass (CPB) time was 71 vs 73 min ( p = .74), respectively. There was no difference in lactates peak ( p = .19) and urine output during CPB ( p = .74). We registered two in-hospital deaths in VAVD cohort (1.6%) vs. no mortality in GVD group ( p = .5). Postoperative cerebral stroke occurred in 1 patient in GVD cohort vs. 0 in VAVD ( p = 1). Severe postoperative acute kidney injury complicated the course in 16 patients in GVD group and in 5 patients who had VAVD ( p = .012). VAVD was associated with a higher number of patients with elevated postoperative AST ( p = .07) and Troponin I ( p = .01) values. Conclusions The use of VAVD during isolated aortic valve replacement was not associated with increased risks of postoperative complications and in-hospital mortality with results that were at least similar to those registered in a matched cohort of patients operated on with GVD.
Novel AI-Based Algorithm for the Automated Measurement of Cervical Sagittal Balance Parameters. A Validation Study on Pre- and Postoperative Radiographs of 129 Patients
Authors: Vogt Sophia , Scholl Carolin , Grover Priyanka , Marks Julian , Dreischarf Marcel , Braumann Ulf-Dietrich , Strube Patrick , Hölzl Alexander , Böhle Sabrina 
Published: January 2024

Study Design Retrospective, mono-centric cohort research study. Objectives The analysis of cervical sagittal balance parameters is essential for preoperative planning and dependent on the physician’s experience. A fully automated artificial intelligence-based algorithm could contribute to an objective analysis and save time. Therefore, this algorithm should be validated in this study. Methods Two surgeons measured C2-C7 lordosis, C1-C7 Sagittal Vertical Axis (SVA), C2-C7-SVA, C7-slope and T1-slope in pre- and postoperative lateral cervical X-rays of 129 patients undergoing anterior cervical surgery. All parameters were measured twice by surgeons and compared to the measurements by the AI algorithm consisting of 4 deep convolutional neural networks. Agreement between raters was quantified, among other metrics, by mean errors and single measure intraclass correlation coefficients for absolute agreement. Results ICC-values for intra- (range: .92-1.0) and inter-rater (.91-1.0) reliability reflect excellent agreement between human raters. The AI-algorithm could determine all parameters with excellent ICC-values (preop:0.80-1.0; postop:0.86-.99). For a comparison between the AI algorithm and 1 surgeon, mean errors were smallest for C1-C7 SVA (preop: −.3 mm (95% CI:-.6 to −.1 mm), post: .3 mm (.0-.7 mm)) and largest for C2-C7 lordosis (preop:-2.2° (−2.9 to −1.6°), postop: 2.3°(-3.0 to −1.7°)). The automatic measurement was possible in 99% and 98% of pre- and postoperative images for all parameters except T1 slope, which had a detection rate of 48% and 51% in pre- and postoperative images. Conclusion This study validates that an AI-algorithm can reliably measure cervical sagittal balance parameters automatically in patients suffering from degenerative spinal diseases. It may simplify manual measurements and autonomously analyze large-scale datasets. Further studies are required to validate the algorithm on a larger and more diverse patient cohort.
Successfully conservative management of the uterus in acute pulmonary embolism during cesarean section for placenta previa: a case report from Tu Du Hospital, Vietnam and literature review
Authors: Vuong Anh Dinh Bao , Pham Thanh Hai , Bui Van Hoang , Nguyen Xuan Trang , Trinh Ngoc Bich , Nguyen Yen Oanh Ngoc , Le Dang Khoa Tran , Nguyen Phuc Nhon 
Published: January 2024

Abstract
Background
Cardiopulmonary collapse is a catastrophic event in cesarean section, which leads to adverse outcomes for both the mother and the fetus. Pulmonary embolism is one of the rare etiologies of this entity. We herein reported the successful management of acute embolism pulmonary associated with cesarean delivery on a healthy pregnant woman at our tertiary referral hospital.

Case presentation
A full-term pregnant woman hospitalized for planned cesarean delivery due to placenta previa without cardiorespiratory diseases. She was scheduled uneventfully for a planned cesarean section. After placental delivery, the patient spontaneously fell into cardiopulmonary collapse and her vital signs deteriorated rapidly. The obstetricians promptly completed the cesarean section and performed all procedures to prevent the PPH and preserve the uterus. At the same time, the anesthesiologists continued to carry out advanced heart-lung resuscitation in order to control her vital signs. After surgery, the multidisciplinary team assessed the patient and found a thrombus in her pulmonary circulation. Therefore, the patient was managed with therapeutic anticoagulation. The patient recovered in good clinical condition and was discharged after 2 weeks without any complications.

Conclusions
The diagnosis of acute pulmonary embolism is extremely difficult due to uncommon occurrence, sudden onset, and non-specific presentation. Awareness of this life-threatening pathology during cesarean delivery should be raised. Interdisciplinary assessment must be essentially established in this life-threatening condition. After the whole conventional management, uterine conservation may be acceptable where applicable. Further data is required to encourage this finding.
ZIF-8 Nanoparticle: A Valuable Tool for Improving Gene Delivery in Sperm-Mediated Gene Transfer
Authors: Sameni Marzieh , Moradbeigi Parisa , Hosseini Sara , Ghaderian Sayyed Mohammad Hossein , Jajarmi Vahid , Miladipour Amir Hossein , Basati Hojat , Abbasi Maryam , Salehi Mohammad 
Published: January 2024

AbstractMetal–organic frameworks (MOFs) are porous materials with unique characteristics that make them well-suited for drug delivery and gene therapy applications. Among the MOFs, zeolitic imidazolate framework-8 (ZIF-8) has emerged as a promising candidate for delivering exogenous DNA into cells. However, the potential of ZIF-8 as a vector for sperm-mediated gene transfer (SMGT) has not yet been thoroughly explored.This investigation aimed to explore the potential of ZIF-8 as a vector for enhancing genetic transfer and transgenesis rates by delivering exogenous DNA into sperm cells. To test this hypothesis, we employed ZIF-8 to deliver a plasmid expressing green fluorescent protein (GFP) into mouse sperm cells and evaluated the efficiency of DNA uptake. Our findings demonstrate that ZIF-8 can efficiently load and deliver exogenous DNA into mouse sperm cells, increasing GFP expression in vitro. These results suggest that ZIF-8 is a valuable tool for enhancing genetic transfer in SMGT, with important implications for developing genetically modified animals for research and commercial purposes. Additionally, our study highlights the potential of ZIF-8 as a novel class of vectors for gene delivery in reproductive biology.Overall, our study provides a foundation for further research into using ZIF-8 and other MOFs as gene delivery systems in reproductive biology and underscores the potential of these materials as promising vectors for gene therapy and drug delivery.
Characterization and analysis of multi-organ full-length transcriptomes in Sphaeropteris brunoniana and Alsophila latebrosa highlight secondary metabolism and chloroplast RNA editing pattern of tree ferns
Authors: Peng Yang , Wang Zhen , Li Minghui , Wang Ting , Su Yingjuan 
Published: January 2024

Abstract
Background
Sphaeropteris brunoniana and Alsophila latebrosa are both old relict and rare tree ferns, which have experienced the constant changes of climate and environment. However, little is known about their high-quality genetic information and related research on environmental adaptation mechanisms of them. In this study, combined with PacBio and Illumina platforms, transcriptomic analysis was conducted on the roots, rachis, and pinna of S. brunoniana and A. latebrosa to identify genes and pathways involved in environmental adaptation. Additionally, based on the transcriptomic data of tree ferns, chloroplast genes were mined to analyze their gene expression levels and RNA editing events.

Results
In the study, we obtained 11,625, 14,391 and 10,099 unigenes of S. brunoniana root, rachis, and pinna, respectively. Similarly, a total of 13,028, 11,431 and 12,144 unigenes were obtained of A. latebrosa root, rachis, and pinna, respectively. According to the enrichment results of differentially expressed genes, a large number of differentially expressed genes were enriched in photosynthesis and secondary metabolic pathways of S. brunoniana and A. latebrosa. Based on gene annotation results and phenylpropanoid synthesis pathways, two lignin synthesis pathways (H-lignin and G-lignin) were characterized of S. brunoniana. Among secondary metabolic pathways of A. latebrosa, three types of WRKY transcription factors were identified. Additionally, based on transcriptome data obtained in this study, reported transcriptome data, and laboratory available transcriptome data, positive selection sites were identified from 18 chloroplast protein-coding genes of four tree ferns. Among them, RNA editing was found in positive selection sites of four tree ferns. RNA editing affected the protein secondary structure of the rbcL gene. Furthermore, the expression level of chloroplast genes indicated high expression of genes related to the chloroplast photosynthetic system in all four species.

Conclusions
Overall, this work provides a comprehensive transcriptome resource of S. brunoniana and A. latebrosa, laying the foundation for future tree fern research.