bluuebunny/crossref_metadata_2025_split huggingface dataset:
From Suspicion to Sincerity in Composition Pedagogy
Authors: Colton Aaron 
Published: October 2023

AbstractRecent advocates of postcritique urge scholars not to read texts suspiciously but instead to regard texts as capable of saying what they mean and, accordingly, to take those meanings seriously. While a suspicious disposition underlies much of introductory composition pedagogy, especially the teaching of argument, postcritique has made little entry into discourses of undergraduate instruction. Attending to the New Sincerity movement in American literature, film, and music after 1980, this essay examines how teaching texts that emphasize their own sincerity (and the difficulty of achieving sincere expression) can encourage students to regard argument and interpretation not as suspicious practices but as means for a generous mode of description that does not sacrifice the complexity of a given text.
Medical students’ knowledge about curriculum development and implementation in public and private medical institutes
Authors: Ehsan Sumera , Ayub Ayesha , Sadiq Ayesha 
Published: October 2023

Objective: To assess the knowledge of undergraduate medical students about curriculum development and implementation.
Methods: A quantitative descriptive study was conducted at a public sector institute and a private sector institute from September, 2022 to December, 2022. Simple random sampling was used and all the undergraduate MBBS students were included in study. Sample size was calculated using open epi and keeping confidence interval at 95% as 316 for FMU students and 218 for AFMDC students. Ethical approval was taken from FMU and permission to collect data was obtained from AFMDC. A Questionnaire was made and distributed among the students and data obtained was analyzed using SPSS 25.0.
Results: Two hundred and forty-seven (49.4%) participants responded that the students don’t have any say in their curriculum, 400 (80%) were of the view that the students must have their opinion in the curriculum and 397 (79.4%) said that students must be involved in the process of planning and implementation of curriculum. When asked about the areas of deficiencies in the current curriculum, 101 (20.2%) pointed new skill, 84 (16.8%) indicated New information, new skills, teaching Methodology and effective teachers, 68 (13.6%) said teaching methodology while 51 (10.2%) indicated new skills and teaching methodology both. Five main themes were identified from the comments of students regarding curriculum, its development and implementation including; 1. Content revision, 2. Teaching methodologies, 3. Assessment, 4. Guidance and orientation and 5. Teacher student relationship.
Conclusion: The undergraduate medical students are aware of the terms related to curriculum, its development and implementation but they are not being involved in any of this process. Content revision, clinical integration from initial years, quality assessment and faculty development are few areas that need improvement from students’ perspectives.
doi: https://doi.org/10.12669/pjms.40.1.7705
How to cite this: Ehsan S, Ayub A, Sadiq A. Medical students’ knowledge about curriculum development and implementation in public and private medical institutes. Pak J Med Sci. 2024;40(1):---------. doi: https://doi.org/10.12669/pjms.40.1.7705
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Association between intestinal microflora and renal function in patients with chronic renal failure: A case-control analysis
Authors: Chen Haixia , Xie Xiaoxiao , Tang Shuming 
Published: October 2023

Objective: To identify the association between the changes in intestinal microflora and renal function in patients with chronic renal failure (CRF).
Methods: This retrospective case-control study included 50 patients with CRF (study group), admitted to the Clinical Laboratory Department of Shenzhen People’s Hospital from March 2021 to May 2022, and 50 healthy individuals (control group). The association between the distribution of intestinal microflora and the glomerular filtration rate (GFR), levels of serum creatinine (SCr), blood urea nitrogen (BUN), and serum cystatin C (CysC) were analyzed.
Results: Intestinal microflora of CRF patients had significantly higher levels of Enterococci compared to the control group (p-Value <0.05), while the levels of Bifidobacterium spp. and Escherichia coli were lower in the study group (p-Value <0.05). GFR was lower, and the levels of BUN, SCr, and CysC were higher in the study group compared to the control group (all p-Value <0.05). GFR, BUN, SCr and CysC levels in the study group negatively correlated with the levels of Bifidobacterium spp. and Lactobacillus spp. (r<0, P<0.05), and positively correlated with the abundance of Enterococcus spp. and Escherichia coli (r>0, P<0.05) in the intestinal microflora.
Conclusions: Changes in intestinal microbiota are associated with a significant decrease in GFR and a marked increase in serum levels of renal function indicators, and alterations in the balance of intestinal microbiota may lead to further aggravation of the renal function damage in patients with CRF.
doi: https://doi.org/10.12669/pjms.40.1.8194
How to cite this: Chen H, Xie X, Tang S. Association between intestinal microflora and renal function in patients with chronic renal failure: A case-control analysis. Pak J Med Sci. 2024;40(1):---------. doi: https://doi.org/10.12669/pjms.40.1.8194
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
A Call-In for Allyship and Anti-Ableism in Intellectual Disability Research
Authors: McDonald Katherine E. , Schwartz Ariel E. , Feldman Micah Fialka , Nelis Tia , Raymaker Dora M. 
Published: October 2023

Abstract
Provoked by decades of grassroots activism, anti-ableist work is underway to advance disability rights. Intellectual disability (ID) researchers can integrate these social changes into their work by interrogating and transforming the beliefs and practices that underpin ID research. We share actionable ideas to foster anti-ableism and allyship in ID research. These include: (1) Learn from and nurture long-term, mutual relationships with people with ID; (2) Amplify the voices of people with ID in institutional structures that influence research; (3) Infuse anti-ableist frameworks into our own research; and (4) Embody a career-long commitment to disability rights, reflexive practice, and growth.
Haplotypic analysis of cox1 from Toxocara canis demonstrates five distinct clades that are not geographically defined
Authors: Martin Katy A. , Jesudoss Chelladurai Jeba R. J. , Bsrat Abrha , Pulaski Cassan , Lee Alice C. Y. , Starkey Lindsay A. , Brewer Matthew T. 
Published: October 2023

BackgroundToxocara canisis a cosmopolitan parasite of dogs that is transmitted transplacentally to puppies resulting in widespread shedding of eggs in the environment. However, it is not clear if there are dominant parasite genotypes that are more common, pathogenic, or likely to be zoonotic.Methods/principle findingsSequences of mitochondrialcox1gene from adult worms were used to compare parasites from the United States with submitted sequences from parasites isolated from dogs in different countries. Our analysis revealed at least 55 haplotypes. While we expected the North American worms to form a distinct cluster, we found haplotypes ofT.canisreported elsewhere existing in this population. Interestingly, combining the sequence data from our study with the available GenBank data, analysis ofcox1sequences results in five distinct clades that are not geographically defined.ConclusionsThe five clades ofT.canisrevealed in this study potentially have unique life histories, traits, or host preferences. Additional investigation is needed to see if these distinct clades represent cryptic species with clinically useful attributes or genotypes with taxonomic value. Evaluation of common mitochondrial genes may reveal distinct populations of zoonoticT.canis.
Evaluation of the efficacy of using indocyanine green associated with fluorescence in sentinel lymph node biopsy
Authors: da Silva Sá Rafael , Von Ah Rodrigues Raquel Fujinohara , Bugalho Luiz Antônio , da Silva Suelen Umbelino , Pinto Nazário Afonso Celso 
Published: October 2023

Introduction
Sentinel lymph node biopsy is the technique recommended for the axillary staging of patients with breast cancer in the initial stages without clinical axillary involvement. Three techniques are widely used globally to detect sentinel lymph nodes: patent blue, the radiopharmaceutical technetium 99 with gamma probe, and the combination of these two.

Objectives
To evaluate the sentinel lymph node detection rate with an innovative technique: indocyanine green (ICG) associated with fluorescence in breast cancer patients, and compare it with patent blue and a combination of patent blue and indocyanine green.

Methods
99 patients were sequentially (not randomly) allocated into 3 arms with 33 patients submitted to sentinel lymph node techniques. One arm underwent patent blue dying, the other indocyanine green, and the third received a combination of both. The detection rates between arms were compared.

Results
The detection rate in identifying the sentinel lymph node was 78.8% with patent blue, 93.9% with indocyanine green, and 100% with the combination. Indocyanine green identified two sentinel nodes in 48.5% of patients; the other groups more commonly had only one node identified. The mean time to sentinel lymph node identification was 20.6 ± 10.7 SD (standard deviation) minutes among patients submitted to the patent blue dye, 8.6 ± 6.6 minutes in the indocyanine green arm, and 10 ± 8.9 minutes in the combined group (P<0.001; Student’s test). The mean surgery time was 69.4 ± 16.9; 55.1 ± 13.9; and 69.4 ± 19.3 minutes respectively (P<0.001; Student’s test).

Conclusions
The sentinel lymph node detection rate by fluorescence using indocyanine green was 93.9%, considered adequate. The rates using patent blue, indocyanine green, and patent blue plus indocyanine green (combined) were significantly different, and the indocyanine green alone is also acceptable, since it has a good performance in sentinel lymph node identification and it can avoid tattooing, with a 100% sentinel lymph node detection rate when combined with patent blue.
Retention of zirconia crown to oxidized titanium base abutment: Experimental research
Authors: Krongvanitchayakul Rawikorn , Kunavisarut Chatchai 
Published: October 2023

Statement of problem
To separate the crown from the titanium base abutment, by using heat, caused oxidization of the titanium base abutment. The effect of this procedure on the retention of a crown is unclear.

Purpose
To compare the resin bond strength and failure type between zirconia crowns and titanium base abutments utilizing four different surface treatments. Surface roughness and morphology of each surface treatment were also investigated.

Material and methods
Forty titanium base abutments (Variobase®) were divided into four groups, 1. Control, 2. Air abraded, 3. Oxidized, and 4. Oxidized-air abraded. Oxidized and oxidized-air abraded groups were debonded from zirconia crowns using constant dry heat at 500 ˚C. For air abraded and oxidized-air abraded groups (after oxidization), the titanium base abutments were air abraded with Al3O2. After cleaning, one specimen of each group was investigated under a non-contact profilometer (50x), then the same samples were investigated under SEM at 25,300,500,1000 magnification and EDS at 30kV of accelerated voltage. All specimens were then cemented (RelyX Ultimate). After aging, with thermocycling under 5C° to 55C°,120 seconds dwell time for 5,000 cycles, bond strength was tested and statistical differences were calculated with One-way ANOVA (p-value <0.05) follow by Tukey test. All separated crowns and titanium base abutments were investigated under a light microscope (20x), using fisher’s exact test for correlation of the failure types.

Results
There was a significant difference in the mean value of tensile bond strength among the control and test groups. Comparisons between control(237.6±46.3N) and oxidized(241.7±46.3N) showed statistically different values from air abraded(372.9±113.2N) when assembled using different surface treatments of the titanium-based abutments. (p-value<0.005) As for failure type, there were statistically significant differences between control versus air abraded, control versus oxidized-air abraded, oxidized versus air abraded, and oxidized versus oxidized-air abraded. (p-value<0.001) The titanium surface morphology shown from the profilometer and SEM was coordinated. Control (Ra 333.8nm) and oxidized (Ra 321.0nm) groups surfaces showed smooth, corrugated surfaces, meanwhile air abraded (Ra 476.0nm) and oxidized-air abraded (Ra 423.8nm) groups showed rough, rugged surfaces.

Conclusion
Heat oxidization of titanium-based abutments did not adversely affect tensile bond strength or the failure mode and surface roughness between titanium base abutments and zirconia crowns. However, air abrasion of the titanium surface increased surface roughness and retentive strength.

Clinical implications
The titanium base abutments that were oxidized under heat treatment did not have an effect on crown retention. Thoroughly air abraded the titanium abutment prior to cementation can increase cement bond strength.
Development of a research mentorship guide and consensus statement for low- and middle-income countries: Results of a modified Delphi process
Authors: Kennedy Fiona , Steiner Annabel , Tucker Joseph D. , Kaba Mirgissa , Abdissa Alemseged , Fongwen Noah , Kpokiri Eneyi E. 
Published: October 2023

Background
Institutional research mentorship is a form of mentorship whereby institutions foster mentor-mentee relationships. Research mentorship improves research effectiveness and supports relationships. However, resources are needed in order to institutionalize research mentorship tailored to low- and middle- income countries (LMICs). The aim of this study was to develop a consensus document on institutionalizing research mentorship through a modified Delphi process as part of the practical guide development process.

Methods
This study used a two-round modified Delphi process, which is an iterative, structured approach of consensus decision making. Each participant was asked about a series of items related to research mentorship using Likert scale questions. Agreement for each item was pre-defined as ≥80% of participants rating the item as “agree” or “strongly agree.” The items that reached agreement, were then discussed during round two at an in-person conference in Ethiopia. A separate group of individuals only participated virtually. For the final consensus survey, response rates and commenting rates (participants who wrote two or more comments) were compared among conference and non-conference participants.

Results
The Delphi process led to the inception of three main themes in terms of developing research mentorship: leveraging existing resources, measuring and evaluating institutional mentorship, and encouraging a research mentorship life cycle. During the virtual first round, 59% (36/61) participants who were emailed completed the survey. In the second round, conference participants had a response rate of 79% (11/14) compared to non-conference participants with a response rate of 45% (21/47). Conference participants had a 100% (11/11) commenting rate whereas non-conference participants had a 38% (8/21) commenting rate. This study achieved consensus in both survey rounds for all 35 items on the consensus document.

Conclusions
The data suggest that an in-person conference may increase participant engagement. The consensus developed through a modified Delphi method directly informed a practical guide on institutionalizing research mentorship in LMICs.
Identification of the genetic basis of pediatric neurogenetic disorders at a tertiary referral hospital in Indonesia: Contribution of whole exome sequencing
Authors: Triono Agung , Iskandar Kristy , Hadiyanto Marissa Leviani , Nugrahanto Andika Priamas , Diantika Kania , Wijayanti Veronica Wulan , Herini Elisabeth Siti 
Published: October 2023

Background
Neurogenetic disorders (NGDs) are complex Mendelian disorders that affect the neurological system. A molecular diagnosis will provide more information about pathophysiology, prognosis, and therapy, including future genetic therapy options. Whole-Exome Sequencing (WES) can rapidly discover the genetic basis in NGDs.

Objective
The purpose of this study was to assess the WES results and its value in diagnosing pediatric NGDs, especially those with unspecified clinical features.

Methods
A retrospective chart review was performed from May 2021- February 2023 in Dr. Sardjito General Hospital, a tertiary referral hospital in Yogyakarta, Indonesia. WES proband only was conducted on children aged 0 to 17 years old who met one or more of the following criteria: (1) epileptic encephalopathy and familial epilepsy; (2) complex neurodevelopmental phenotypes; (3) leukodystrophy; (4) movement disorders; and (5) neurocutaneous disorder. The WES was conducted in the certified laboratory, 3Billion, in Seoul, Korea.

Results
The diagnosis yield of WES in our study was 45% (9/20). We identified nine positive results, including eight pathogenic single nucleotide variants (SNVs) in 8 genes (KCNQ2, ARSA, UBE3A, IRF2BPL, ATM, MECP2, TSC2, and NF1), and one variant with uncertain significance (VUS) in the ADK gene that has not been able to explain the observed clinical features. Of the nine patients with positive WES results, five had missense mutations, three frameshift mutations, and one nonsense mutation. Additionally, we identified two suggestive copy number variants (CNVs) in 15q11.2q13.1 and 1p31.3.

Conclusions
Whole-Exome Sequencing is an essential diagnostic tool for pediatric NGDs, especially those with unspecified clinical features. It ends multi-year diagnostic odysseys, provides personalized medicine therapy, and optimizes genetic counselling for these families.
Substance use and pre-hospital crash injury severity among U.S. older adults: A five-year national cross-sectional study
Authors: Adeyemi Oluwaseun , Bukur Marko , Berry Cherisse , DiMaggio Charles , Grudzen Corita R. , Konda Sanjit , Adenikinju Abidemi , Cuthel Allison , Bouillon-Minois Jean-Baptiste , Akinsola Omotola , Moore Alison , McCormack Ryan , Chodosh Joshua 
Published: October 2023

Background
Alcohol and drug use (substance use) is a risk factor for crash involvement.

Objectives
To assess the association between substance use and crash injury severity among older adults and how the relationship differs by rurality/urbanicity.

Methods
We pooled 2017–2021 cross-sectional data from the United States National Emergency Medical Service (EMS) Information System. We measured injury severity (low acuity, emergent, critical, and fatal) predicted by substance use, defined as self-reported or officer-reported alcohol and/or drug use. We controlled for age, sex, race/ethnicity, road user type, anatomical injured region, roadway crash, rurality/urbanicity, time of the day, and EMS response time. We performed a partial proportional ordinal logistic regression and reported the odds of worse injury outcomes (emergent, critical, and fatal injuries) compared to low acuity injuries, and the predicted probabilities by rurality/urbanicity.

Results
Our sample consisted of 252,790 older adults (65 years and older) road users. Approximately 67%, 25%, 6%, and 1% sustained low acuity, emergent, critical, and fatal injuries, respectively. Substance use was reported in approximately 3% of the population, and this proportion did not significantly differ by rurality/urbanicity. After controlling for patient, crash, and injury characteristics, substance use was associated with 36% increased odds of worse injury severity. Compared to urban areas, the predicted probabilities of emergent, critical, and fatal injuries were higher in rural and suburban areas.

Conclusion
Substance use is associated with worse older adult crash injury severity and the injury severity is higher in rural and suburban areas compared to urban areas.
Unfinished Women Cry in No Man’s Land While a Bird Dies in a Gilded Cage, Aishah Rahman, directed by Chyna Michele
Authors: Garner Sloan Elle 
Published: October 2023

Review of: Unfinished Women Cry in No Man’s Land While a Bird Dies in a Gilded Cage, Aishah Rahman, directed by Chyna Michele
Camden Repertory Theater, Camden, NJ, 25 February 2023
Facing Disaster: Ordinary Fictions, Resilience, and the Demand for Recognition in Eastern DR Congo
Authors: Le Lay Maëline 
Published: October 2023

AbstractIn DR Congo, there is a proliferation of fictions and spoken word texts that addresses aspects of the on-going conflict. Fiction in Congo does not concern itself with the rules of literary orthodoxy (verisimilitude, linguistic correctness, references), nor does it rely on the existence of a literary and editorial system that is structured and operating to guarantee a predetermined readership. Its main objective is to express emotions in an aesthetic way that touches the hearts of readers and spectators. However, the primary motivation for these proliferating literary initiatives is to resonate in the social space of the place from which they originate. In this respect, the productions examined here are ordinary aesthetic creations distilled through the alembic of everyday existence. Beginning with the observation of a profusion of love stories in the literature produced in the Congo during the last quarter-century, I demonstrate how the particular orientation of these contemporary love fictions responds to societal objectives regarding social cohesion and crisis management, particularly the call for resilience. I then analyse how the issues involved in this injunction are related tocare, which is presented as the only possible, acceptable, and even desirable path in this context of violence.
The State of Sport Science Around the World: A Roundtable Discussion
Authors: Suchomel Timothy J. , McMahon Eric L. 
Published: October 2023

ABSTRACTAlthough sport science as a profession has advanced in some countries, there are other countries where it is still in its infancy. This roundtable was designed to identify the perceived state of sport science in different countries around the world, including common themes that may be used to help further advance an emerging profession. Several international panelists discussed the sports that most commonly use sport science services, their opinions about the sport scientist job task and responsibilities, the role of education in preparing sport scientists for the field, and sport science career opportunities around the world. Furthermore, the panelists shared their opinions about the current state of sport science, and their hopes for a brighter future of sport science.