bluuebunny/crossref_metadata_2025_split huggingface dataset:
Electroconvulsive therapy related anxiety in patients with depression: The influence of cognitive coping styles
Authors: Verledens Chelsea , Obbels Jasmien , Van den Eynde Liese , Pilato Eva , Verspecht Shauni , Hebbrecht Kaat , De Schuyteneer Emma , Vansteelandt Kristof , Sienaert Pascal 
Published: November 2023

AbstractIntroductionElectroconvulsive therapy (ECT) related anxiety (ERA) is a common phenomenon with high individual variability. The way patients cognitively cope with the prospects of receiving ECT could be a mechanism explaining individual differences in ERA. Cognitive coping like monitoring (information seeking, paying attention to consequences) and blunting (seeking distraction and reassurance) has been linked to anxiety in various medical settings, with monitoring leading to more and blunting to less anxiety. How cognitive coping is related to ERA, is unknown.MethodsThe sample consisted of 71 patients with unipolar or bipolar depression referred for ECT. Cognitive coping was assessed at baseline, while ERA was measured each morning before the ECT session. Using a Linear Mixed Model, the influence of cognitive coping styles on ERA was investigated.ResultsBlunting was associated with lower levels of ERA (p = 0.037) and monitoring tended to be associated with higher levels of ERA (p = 0.057) throughout the ECT course. Patients with a depression with psychotic features scored significantly higher on monitoring, but even after controlling for monitoring they showed a stronger decline in ERA during treatment compared to patients without psychotic features.ConclusionCognitive coping style contributes to individual differences in ERA. Blunting is a protective factor, leading to lower levels of ERA throughout the ECT course. On the contrary, patients with a higher monitoring style tend to experience higher levels of ERA. Further insights in these coping mechanisms may help to tailor future treatment to individual patients and reduce ERA before and during ECT treatment.
Anthropology's comparative value(s)
Authors: Lederman Rena 
Published: November 2023

AbstractAnthropologists often have to justify their research to ethics and funding committees composed mostly of mainstream social‐behavioral scientists. In making their case, anthropologists face a dilemma in representing their discipline's distinctive research practices. For many anthropologists, the value of ethnographic work derives from its global comparativism and socially embedded realism; for students especially, ethnographic fieldwork's value relative to alternatives is rooted in field‐workers’ sustained relationships with their interlocutors. But from a conventionally objectivist social‐behavioral science perspective, being with and learning from people on the latter's terms is incoherent as science. Socially embedded research methods are also devalued by ethics review protocols, which situate replicability as the social‐behavioral research norm. A comparative understanding of anthropology's disciplinary neighborhood may provide students with critical resources for reinventing anthropology's distinctively grounded research value(s) for future generations.
Alterations in testicular positioning after normal descent: acquired cryptorchidism
Authors: Grande‐Moreillo Carme , Fuentes‐Carretero Sara , Margarit‐Mallol Jaume , Pérez‐López Carlos , Rodríguez‐Molinero Alejandro 
Published: November 2023

AbstractBackgroundAcquired cryptorchidism or acquired undescended testis (UDT) is defined as the displacement of a testicle outside the scrotal sac after normal descent has been verified. There are still no clear guidelines on its management.ObjectivesTo analyze patients who underwent surgery for UDT in our setting to determine the prevalence of acquired cryptorchidism and to analyze the demographic and clinical characteristics of the population of children diagnosed with both acquired and congenital cryptorchidism, the age of presentation of both entities and the percentage of bilateral involvement.Materials and methodsThis was a retrospective descriptive study using data from the clinical history of patients who underwent surgery for cryptorchidism between 2011 and 2022. The type of cryptorchidism, acquired or congenital, was recorded. Demographic and clinical data were collected.ResultsA total of 367 patients and 442 testicular units were included in the study (75 patients had bilateral involvement).In 54.75% (95% CI: 50.09%–59.40%) of the cases analyzed, cryptorchidism was acquired, and the mean age at the time of surgery was 7.39 years (SD 2.95). Twenty percent (95% CI: 16.29%–24.58%) of the patients presented with bilateral cryptorchidism and 64% (95% CI: 52.88%–75.11%) out of them were acquired on both sides. The diagnosis was metachronous in 42.6% (95% CI: 31.21%–54.12%) of bilateral cryptorchidism cases.Discussion and conclusionAcquired cryptorchidism accounts for more than half of cryptorchidism cases requiring surgery in our setting, with a clearly different age of presentation than that for congenital cryptorchidism. Therefore, it is necessary to monitor the presence of the testes in the scrotal sac until adolescence. It is also important to monitor patients with a history of cryptorchidism, not only for the management of the operated testicle but also for the early identification of patients who will develop metachronous contralateral cryptorchidism.
Full robotic cholecystectomy: first worldwide experiences with HUGO RAS surgical platform
Authors: Caputo Damiano , Farolfi Tommaso , Molina Chiara , Coppola Roberto 
Published: November 2023

AbstractBackgroundThe Hugo RAS™ system (Medtronic, Minneapolis, MN, USA), approved for gynaecological and urological procedures, has been recently certified for the use in few general surgeries. Only bariatric and colorectal procedures have been described so far.MethodsHere, we report the first worldwide experience with three cases of full‐robotic cholecystectomies with the Hugo RAS™ system.ResultsA description of the operative room setup, of the docking angles and details of the procedures is reported. Docking time was 12, 10, and 6 min, respectively. The total operative time was 105 min in the first case, 100 min in the second and 88 in the third case. Intra‐ and post‐operative courses were uneventful.ConclusionsWith this pre‐defined set up, the innovative conformation of Hugo RAS™ system can safely allow performing full robotic cholecystectomy avoiding the need for additional ports.
Are there gender differences in promotion–prevention self‐regulatory focus?
Authors: Gutermuth Dinah , Hamstra Melvyn R. W. 
Published: November 2023

AbstractThe purpose of this research is to examine gender differences in promotion/prevention self‐regulatory focus, a dispositional motivational orientation with major implications for human functioning. First, a review of literature using social cognitive theory as a framework suggests that, driven by socialization processes, (1) women may on average be more prevention focused than men – meaning more vigilant to maintain a secure status quo, whereas (2) men may on average be more promotion focused than women – meaning more eager to advance to a better situation than their status quo. Second, we provide data to examine these possible gender differences in self‐regulatory focus with secondary analyses of (a) our own existing data on dispositional regulatory focus and of (b) a large scale, representative panel study (LISS Survey). The data suggest a highly consistent difference with women being more prevention focused than men, while the difference in promotion focus is much smaller and is only found in European samples. Auxiliary data suggest promotion‐focused women hold less traditional gender role beliefs as well as showing that regulatory focus partially explains examples of behavioural differences between men and women. The analysis of gender difference in regulatory focus sheds new light on gender differences and biases already known, and on regulatory focus, and as such opens up many new and important areas of future inquiry.
Evaluation of ocular surface following PreserFlo Microshunt implantation: Functional outcomes and quality of life
Authors: Gambini Gloria , Carlà Matteo Mario , Giannuzzi Federico , Savastano Alfonso , Caporossi Tomaso , Baldascino Antonio , Iannetta Danilo , Vielmo Lorenzo , Rizzo Stanislao 
Published: November 2023

AbstractBackgroundThis study aimed to evaluate the impact of PreserFlo Microshunt on the ocular surface, focusing on both objective and subjective parameters.MethodsProspective‐observational study on 48 eyes undergoing PreserFlo Microshunt implantation, standalone or combined with phacoemulsification. At baseline, 1‐month, 6‐months and 12‐months post‐operative follow‐ups, we performed Ocular Surface Disease Index (OSDI) questionnaire, Schirmer's test (ST), Tear‐film break‐up time (TBUT), fluoresceine staining (FS), tear osmolarity and minimum corneal epithelial thickness (Epi‐ThkMIN.) measurements.ResultsOSDI score improved from 37.43 ± 17.49 at baseline, to 24.13 ± 12.55 at 1‐month (p = 0.003) and to 12.89 ± 8.54 and 13.09 ± 10.22 at 6‐months and 12‐months (p < 0.0001). TBUT and ST, in a similar way, non‐significantly increased at 1‐month, but then improved at 6‐months and 12‐months (p < 0.05 for both). Tear osmolarity significantly decreased from 308.2 ± 7.3 mOsm/L at baseline, to 303.3 ± 8.2 mOsm/L, 295.6.2 ± 7.0 mOsm/L and 297.6 ± 6.8 mOsm/L at 1‐month, 6‐months and 12‐months (p < 0.05 for all). Epi‐ThkMIN was stable when comparing baseline (44.9 ± 5.7 μm) and 1‐month (p = 0.28), and successively increased in 6‐months (47.8 ± 5.5 μm, p = 0.02) and 12‐months (48.0 ± 3.6 μm, p = 0.01). In subgroup analysis, OSDI score and tear osmolarity were significantly higher at 1‐month in combined group compared to standalone group (p = 0.03 and p = 0.02, respectively), but reaching comparable values in successive follow‐ups. Further, Oxford scale grades for FS were significantly improved when comparing baseline–6‐months and baseline–12‐months.ConclusionPreserFlo implantation improved ocular surface subjective symptoms, increased TBUT and ST, and reduced FS, highlighting the potential benefits of this surgical intervention. Moreover, we reported significant improvements of tear osmolarity and corneal epithelium.
A novel RNF125 variant associated with Tenorio syndrome alters ubiquitin chain binding
Authors: Barzak Fareeda M. , Lu Anita , Geltzeiler Alexa R. , Ledgerwood Elizabeth C. , Chung Wendy K. , Day Catherine L. 
Published: November 2023

AbstractA key signalling pathway required for clearance of viruses from host cells relies on the receptor protein, retinoic acid‐inducible gene I (RIG‐I). The activity of RIG‐I is tightly controlled, and once bound to viral dsRNA, addition of lysine 63‐linked ubiquitin chains activates signalling. Meanwhile, the addition of lysine 48‐linked ubiquitin chains to RIG‐I is required to terminate signalling when the infection has been resolved. Really interesting new gene (RING) finger protein 125 (RNF125) is the E3 ligase responsible for addition of the ubiquitin chains that terminate signalling, with disruption of its function associated with Tenorio syndrome. Here we describe a novel RNF125 gene variant in an individual with clinical symptoms including intellectual disability, macrocephaly and congenital heart disease, consistent with Tenorio syndrome. The newly identified Tenorio syndrome‐associated variant [(NM_017831.4):c.670G>C p.Glu224Gln] is the first to be found in the ubiquitin interaction motif (UIM) of RNF125. While the E3 ligase activity of this RNF125 variant is retained, it has an impaired ability to interact with lysine 63‐linked ubiquitin chains. The function of the UIM in RNF125 is uncertain; however, this study suggests that the UIM binds lysine 63‐linked ubiquitin chains, and that this interaction is required for the normal function of RNF125.
Jawbone measurements of edentulous sites related to implant planning using magnetic resonance imaging compared to cone beam computed tomography: An ex vivo study
Authors: Fuglsig Joao Marcus de Carvalho e Silva , Schropp Lars , Hansen Brian , Wenzel Ann , Spin‐Neto Rubens 
Published: November 2023

AbstractAimTo compare measurements on images obtained by magnetic resonance imaging (MRI) and cone beam CT (CBCT) for height, width, and area in alveolar bone sites in human jaw specimens.Material and MethodsForty edentulous alveolar posterior sites in human cadaver specimens were imaged using CBCT scanners, and with zero‐echo‐time MRI (ZTE‐MRI). Semi‐automatic volume registration was performed to generate representative coronal sections of the sites related to implant planning. ZTE‐MRI sections were also presented after grayscale inversion (INV MRI). Three observers measured bone height, bone width 5 mm from the alveolar crest, and bone area stretching from the width measurement to the top of the alveolar crest in the images. Interobserver agreement was assessed by intra‐class correlation coefficients (ICC). The measurements were analyzed using two‐way repeated measures ANOVA factoring observer and image type.ResultsICC was >0.95 for bone height, width, and bone area. No significant differences among observers (p = 0.14) or image type (p = 0.60) were found for bone height. For bone width, observer (p = 0.14) was not a significant factor, while ZTE‐MRI produced width estimates that were significantly different and systematically smaller than CBCT‐based estimates (p ≤ 0.001). Observer (p = 0.06) was not a significant factor regarding the bone area measurements, contrary to the imaging type where ZTE‐MRI led to significantly smaller area estimates than CBCT (p ≤ 0.001).ConclusionBone height measurements were essentially equivalent using CBCT and MRI. This was found regardless of grayscale choice for the MRI. However, ZTE‐MRI resulted in smaller estimates of bone width and area.
Comparison of the effectiveness, safety, and costs of anti‐Parkinson drugs: A multiple‐center retrospective study
Authors: Li Wenting , Zhang Hua , Zhang Yuan , Wang Ke , Hui Jiaojiao , Yi Zhanmiao 
Published: November 2023

AbstractAimsThis study aimed to systematically compare the effectiveness, safety, and costs of different anti‐Parkinson drugs (APDs).MethodsThis is a multi‐center study that retrospectively analyzed the data of 8420 outpatients with PD from 2014 to 2019 across 30 tertiary hospitals in China. The effectiveness was evaluated by changes in total dosages of APDs, normalized by levodopa equivalent dose (LED) and presented as ΔLEDs; levodopa equivalent dose cost (LEDc) represented the daily cost of APDs; and newly added diagnostics were represented as APDs‐related adverse events.ResultsA total of 384 patients with eligible medical records for three consecutive years were enrolled. Patients treated with carbidopa/levodopa or levodopa/benserazide had significantly lower mean ΔLEDs than other groups (p < 0.01), followed by pramipexole and selegiline. The piribedil group had the highest ΔLEDs, with mean differences of 112.56–355.04 mg compared to other groups (p < 0.01). Meanwhile, LEDc in the levodopa/benserazide, carbidopa/levodopa, and piribedil groups were significantly lower than those in pramipexole or selegiline groups ($0.088–0.135/day for levodopa/benserazide; $0.070–0.126/day for carbidopa/levodopa; $0.112–0.138/day for piribedil; $0.290–0.332/day for pramipexole; $0.229–0.544/day for selegiline; p < 0.01). Patients with piribedil had more adverse events, with an incidence rate of 35.7%, followed by levodopa/benserazide (25.6%), selegiline (23.5%), carbidopa/levodopa (23.3%), and pramipexole (16.4%). Pramipexole showed a lower incidence rate of adverse events than piribedil, including neuropsychiatric symptoms (p = 0.006), headache/dizziness (p = 0.016), and gastrointestinal symptoms (p = 0.031).ConclusionsCarbidopa/levodopa or levodopa/benserazide might exhibit better clinical improvement with less medical cost, while piribedil presented less clinical improvement but a higher risk of headache/dizziness, gastrointestinal, and neuropsychiatric symptoms.
Academic seminars as tool for clinical and translational science education and dissemination: Perceptions and priorities in the COVID‐19 era
Authors: Chen Katherine L. , Oronce Carlos Irwin A. , Calderón Nancy E. , Kahn Katherine L. 
Published: November 2023

AbstractAcademic seminars are an important venue through which investigators in health services research (HSR) and other clinical and translational science disciplines can share their work, gather feedback, and connect with colleagues. However, the format and focus of these seminars shifted abruptly when the coronavirus disease 2019 (COVID‐19) pandemic necessitated social distancing and underscored the salience of health equity. Little is known about how contemporary academic seminars are meeting the evolving needs of the HSR community. We surveyed 2021–2022 participants in a virtual HSR seminar series to understand experiences of and priorities for the seminars. We also compared results stratified by self‐reported under‐represented minority (URM) status. Of 45 respondents (including 26 faculty members, 8 trainees, 9 staff members, and 2 community partners), 38% self‐identified as URM. Participants reported high satisfaction with seminar quality, diversity of topics, and audience participation (median ≥4 for all outcomes in Likert‐scaled items where 5 = very satisfied). Knowledge acquisition, understanding of research methods, and collaboration were commonly cited as benefits of seminar attendance. Implementation science content and external collaboration were most often endorsed as priorities for future seminars. URM participants were over three times more likely than non‐URM participants to cite learning about engaging community stakeholders and historically excluded populations as a benefit of seminar participation. Virtual academic seminars can be an effective modality for knowledge sharing and collaboration worth continuing after COVID‐19 restrictions are lifted. Emphasizing equity, diversity, and inclusion (EDI) values in these seminars may hold potential for advancing academic departments' own EDI goals.
One nodule–one punction–one slide: Optimizing thyroid fine‐needle aspiration for a digital workflow
Authors: Maia Ariana , Carvalho Bárbara , Vale João , Curado Mónica , Ryan Carmel , Polónia António , Eloy Catarina 
Published: November 2023

AbstractObjectiveInterventional pathologists have expanded their expertise by acquiring proficiency in ultrasound‐guided thyroid fine‐needle aspiration biopsy (FNAB) and are now required to optimize punction procedures due to low resources and digital workflows. The aim of this study is to compare FNAB sample adequacy in two series with one versus two slides available for cytopathological analysis and its influence on diagnosis categorization, time taken to reach a final diagnosis, scanning time and size of the digital files produced.MethodsPatients were retrospectively selected based on the sampling of thyroid nodules using either two glass slides (two‐slide group) or one slide only (one‐slide group) and cytological diagnosis was performed using the second edition of the Bethesda system. For each group, the initial 15 cases were sorted to be scanned.ResultsFrom a total of 713 procedures, 328 were sampled into two slides and 385 on one slide only. No significant differences were found regarding nodule size, location or EU‐TIRADS classification between the two groups. The one‐slide group did not exhibit a higher prevalence of non‐diagnostic or atypia of undetermined significance (AUS) categories. As expected, the mean time taken to finalize diagnoses in cases where only one slide was prepared was 1.2 days faster. Scanning time and total file size were also significantly smaller in the one‐slide group.ConclusionsAdopting the ‘one nodule–one puncture–one slide’ strategy for thyroid FNAB optimization enhances procedural efficiency in digital workflows, leading to cost savings without compromising diagnostic accuracy.
Short‐term outcomes of endoscopic resection for colorectal neuroendocrine tumors: Japanese multicenter prospective C‐NET STUDY
Authors: Ito Sayo , Hotta Kinichi , Sekiguchi Masau , Takeuchi Yoji , Oka Shiro , Yamamoto Hironori , Shinmura Kensuke , Harada Keita , Uraoka Toshio , Hisabe Takashi , Sano Yasushi , Kondo Hitoshi , Horimatsu Takahiro , Kikuchi Hidezumi , Kawamura Takuji , Nagata Shinji , Yamamoto Katsumi , Tajika Masahiro , Tsuji Shigetsugu , Kusaka Toshihiro , Okuyama Yusuke , Yoshida Naohisa , Moriyama Tomohiko , Hasebe Aki , So Suketo , Saito Yutaka , Nakahira Hiroko , Ishikawa Hideki , Matsuda Takahisa ,   the C‐NET STUDY Group
Published: November 2023

ObjectivesThe incidence of colorectal neuroendocrine tumors (NETs) has increased with colorectal cancer screening programs and increased colonoscopies. The management of colorectal NETs has recently shifted from radical surgery to endoscopic resection. We aimed to evaluate the short‐term outcomes of various methods of endoscopic resection for colorectal NETs.MethodsAmong those registered in the C‐NET STUDY, patients with colorectal NETs who underwent endoscopic treatment as the initial therapy were included. Short‐term outcomes, such as the en bloc resection rate and R0 resection (en bloc resection with tumor‐free margin) rate, were analyzed based on treatment modalities.ResultsA total of 472 patients with 477 colorectal NETs received endoscopic treatment. Of these, 418 patients with 421 lesions who met the eligibility criteria were included in the analysis. The median age of the patients was 55 years, and 56.9% of them were men. The lower rectum was the most commonly affected site (88.6%), and lesions <10 mm accounted for 87% of the cases. Endoscopic submucosal resection with a ligation device (ESMR‐L, 56.5%) was the most common method, followed by endoscopic submucosal dissection (ESD, 31.4%) and endoscopic mucosal resection using a cap (EMR‐C, 8.5%). R0 resection rates <10 mm were 95.5%, 94.8%, and 94.3% for ESMR‐L, ESD, and EMR‐C, respectively. All 16 (3.8%) patients who developed treatment‐related complications could be treated conservatively. Overall, 23 (5.5%) patients had incomplete resection without independent clinicopathological risk factors.ConclusionESMR‐L, ESD, and EMR‐C were equally effective and safe for colorectal NETs with a diameter <10 mm.
“I Can't Read This”: Plagiarism, Biopolitics, and The Production of The Trans‐Dividual Student
Authors: Iantosca Tony 
Published: November 2023

AbstractIn this paper, Tony Iantosca situates the academic integrity policies of US colleges and universities, as well as student plagiarism, in biopolitical frameworks. By examining the aporias that result from student plagiarism in the context of neoliberal knowledge production, which produces and depends upon individualized, skills‐bearing students, Iantosca interrogates what educators can learn philosophically and pedagogically from the mutual misrecognition that occurs between institutional policy and the transgressing student. He frames this discussion with Michel Foucault's classic work on biopolitics as well as Roberto Esposito's immunitary paradigm in order to examine the implications of student illegibility for what Bernard Stiegler has called education's trans‐individuating potential. The argument that emerges is that student plagiarism has multiple, contradictory significances that can nonetheless teach educators important lessons about property and individualism, and these lessons must be retained as we reinitiate, rather than punish, plagiarizing students. Iantosca then closes the paper with a brief consideration of the pedagogical implications of this argument.