bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the effect of input parameters on tool wear in incremental sheet metal forming
Authors: Oraon Manish , Prasad Ranjeet , Sharma Vinay 
Published: October 2023

Abstract
Over the years incremental sheet metal forming (ISMF) has developed as a futuristic technique in which the metal sheets are transformed into the final product with the use of a solid metallic rod having a designed end, rather than a dedicated die. The production lead time is quite high in this process as compared to the conventional sheet forming methods. ISMF is most suitable for developing model for the purpose of research and development, manufacturing of the customized part and for low-volume production. Tool life is an important criterion for determining feasibility of any manufacturing process. The sliding of the forming tool over the clamped metal worksheet during the ISMF is another important aspect for understanding the tool-wearing behaviour. The present study has investigated the wearing of the 440C grade steel forming tool during the ISMF of aluminum grade AA3003-O. It has examined the process statistically to establish that the step downsize (P = 0.021) and sheet metal thickness (P = 0.005) significantly influence the wearing of 440C steel tool. The coefficient of performance, i.e., R
2 has been reported as 92.0 % with an adjusted R
2 of 81.9 %.
Umbilical cord blood hematological parameters in predicting early onset neonatal sepsis (EOS) – a prospective cohort study
Authors: Samson Smrithi Marie , Anandhi Chandramohan , Sharmila Ramar Rathi 
Published: October 2023

Abstract

Objectives
In low and middle income countries, there is a need for affordable and accurate biomarkers to identify neonates at risk of early onset neonatal sepsis (EOS). Cord blood hematological parameters if reliable and accurate for the detection of EOS are cost effective and can reduce the need for repeated venipuncture in the neonate.

Methods
In this prospective cohort study, the umbilical cord parameters of newborns with gestational age >34 weeks were collected. These neonates were followed up for 72 h and septic screen was employed in those babies who had risk factors or developed clinical features of sepsis. The cord blood parameters of the normal newborn and those who had sepsis were analyzed.

Results
A total of 513 neonates were enrolled for the study, 32 required septic screening of whom 13 neonates were found to meet the criteria for sepsis: either blood culture positive or sepsis screen positive with clinical features. Cord blood parameters were analyzed using independent t test. Red cell distribution width (RDW) and band cells were statistically significant (p 0.007 and 0.009 respectively) between the septic and normal neonates. Increased RDW had a sensitivity of 61.54 %, specificity of 54.60 %. Increased band cells with a cut off of >15 cells had a sensitivity of 7.7 % with specificity of 100 % with higher numbers in septic neonates. Increased RDW and band cells in combination had sensitivity of 61.54 % and specificity of 54.6 %.

Conclusions
RDW and band cell can be potential markers of EOS in cord blood but require further study in a larger population.
Zerstörungsfreie Prüfung von Nahtabdichtungen im Automobilbau
Authors: Birk Alexander , Klaus Fabian , Altin Alan , Margies Lennard , Müller Rainer 
Published: October 2023

Abstract
Die Nahtabdichtung ist im Automobilbau elementar für eine dichte Fahrzeugkarosserie. Während die Applikationsprozesse zu größten Teilen automatisiert sind, ist die Qualitätsprüfung der Nahtabdichtung ein aufwändiger Prozess. Um in Zukunft Aufwände und Kosten für Prüfprozesse zu reduzieren, beschäftigt sich diese Untersuchung mit einer Möglichkeit der zerstörungsfreien und berührungslosen Qualitätsprüfung von Nahtabdichtungen an Fahrzeugen. In diesem Projekt erfolgt eine Untersuchung der Möglichkeiten zur Qualitätsprüfung von Nahtabdichtungen mittels aktiver Thermografie. Dieses Verfahren dient zur Detektion von strukturellen Defekten im Bauwesen, aber auch zur Prüfung von dünnwandigen Verbundbauteilen. Die Ergebnisse der Messreihe zeigen eine Fähigkeit des Verfahrens für bestimmte Fehlerbilder, die durch messbare lokale Temperaturdifferenzen identifizierbar sind.
Wasserstoffeinsatz im Industriesektor
Authors: Jelschow Vladimir , Schabernack Nils , Mais Franziska , Gramberg Till , Gross Erwin , Sauer Alexander 
Published: October 2023

Abstract
Dieser Beitrag präsentiert das Ergebnis der Studienanalyse zur Ermittlung des künftigen Wasserstoffbedarfs im Industriesektor der Region Schwarzwald. Zur Identifikation der für einen positiven Hochlauf der Wasserstoffwirtschaft erforderlichen Maßnahmen führten die Autor:innen Interviews mit Expert:innen aus der Industrie, der Forschung und dem Dienstleistungsbereich. Eine Roadmap fasst den identifizierten Wasserstoffbedarf und die erforderlichen Maßnahmen zusammen.
Sensorik zur Maßfehlerkompensation beim Schlichtfräsen
Authors: Evers Lasse , Müller Matthias , Möller Carsten , Hendrik Dege Jan 
Published: October 2023

Abstract
Dem Schlichtfräsen dünnwandiger Strukturbauteilen aus der Luftfahrt ist eine Produktivitätsgrenze gesetzt. Größere Eingriffsbedingungen führen zur Deformation des Werkstücks und damit zu einem bleibenden Maßfehler, der die engen Toleranzanforderungen nicht erfüllt. In dieser Arbeit werden mithilfe ausgewählter Sensorik die Werkstückdeformation im Prozess aufgenommen und daraus Werkzeugbahnen abgeleitet, die den Maßfehler kompensieren.
Propaganda, Social Media, and Political Participation: Quantitative Analysis of The Influence of Propaganda #2019gantipresiden on Outcomes and Levels of Political Participation of National Voters in The 2019 Presidential Elections
Authors: Rosyidin Iding , Ruswandi Bambang 
Published: October 2023

In politics, propaganda is often used, for example, during general elections. Among the propaganda media that can be used is social media such as Twitter. During the 2019 Indonesian presidential election, one of the supporters of the presidential candidate pair carried out propaganda, namely the #2019gantipresiden tweet. From a propaganda perspective, this hashtag can be categorized as the bandwagon type of propaganda (Shabo, 2008), a technique that asks audiences to follow propagandist ideas. This study aims to determine the influence of #2019gantipresiden tweets on the results and participation rates in the 2019 Presidential Election. The data used in this study are tweets with the hashtag #2019gantipresiden spread across 34 provinces in Indonesia. Data was collected over three months, namely May, June, and July 2018, when this hashtag was first launched. In addition, data from the results of the 2019 Presidential Election were obtained from the KPU. The data analysis results show a significant relationship between the number of #2019gantipresiden tweets and the Jokowi-Ma'ruf vote. However, this relationship becomes insignificant when including Prabowo-Sandi's vote acquisition as a control variable and has the opportunity to reduce the vote gain obtained by the Jokowi-Ma'ruf pair. This result is inversely proportional to the relationship between the number of #2019gantipresiden tweets and Prabowo-Sandi's vote gain, where the relationship between the two remains significant whether controlled by Jokowo-Ma'ruf vote gain or not. The appearance of the #2019gantipresiden tweet also triggered public participation in the 2019 presidential election by giving it an influence of 31.4%.
Arithmetic textbooks panorama of the decade after the lifting of the ban on Lithuanian publications
Authors: Banionis Juozas 
Published: October 2023

In 1904 with the lifting of the ban on Lithuanian publications by Russian czar government and in 1906 with giving the permit to teach arithmetics in mother tongue at primary schools the legal publishing of Lithuanian arithmetic textbooks started. Already in 1906 even three arithmetic textbooks were published. These were two parts of ``Arithmetic Taskbook“ by Pranas Mašiotas, the first part of ``Collection of Arithmetic Tasks and Examples“ by Petras Bendorius and Pranas Daugirda and two parts of translated from Polish ``Arithmetic Tasks and Examples“ by Stanislaw Thom. All the books step by step explained in the Lithuanian language four arithmetic operations up to ten, later a hundred and finally up to a thousand.In 1909 two important books were published: the second part of the textbook by Petras Bendorius and Pranas Daugirda and ``Elementary Arithmetics“ by Petras Mikolainis. The latter textbook could be distinguished for methodical instructions.In 1909–1916 Juozas Damijonaitis prepared and published two parts of ``Arithmetic Textbook“. The book was recompiled into three parts during the period of the Republic of Lithuania (in 1918–1940). It became popular and was constantly republished.When forming of arithmetic basics was coming to end in 1916 ``The Short Science of Arithmetics“ by S. Thom (1916) appeared in the Lithuanian language, where the theory of arithmetics was presented.
Upper-bound estimates for weighted sums satisfying Cramer’s condition
Authors: Čekanavičius Vydas , Elijio Aistė 
Published: October 2023

Let S = ω1S1 + ω2S2 + ⋯ + ωNSN. Here Sj is the sum of identically distributed random variables and ωj > 0 denotes weight. We consider the case, when Sj is the sum of independent random variables satisfying Cramer’s condition. Upper-bounds for the accuracy of compound Poisson first and second order approximations in uniformmetric are established.
Global transcriptomic analysis of breast cancer and normal mammary epithelial cells infected with Borrelia burgdorferi
Authors: Khatri Vishwa A. , Paul Sambuddha , Patel Niraj Jatin , Thippani Sahaja , Sawant Janhavi Y. , Durkee Katie L. , Murphy Cassandra L. , Aleman Geneve Ortiz , Valentino Justine A. , Jathan Jasmine , Melillo Anthony , Sapi Eva 
Published: October 2023

AbstractThe bacterial spirochete Borrelia burgdorferi, the causative agent of Lyme Disease, can disseminate and colonize various tissues and organs, orchestrating severe clinical symptoms including arthritis, carditis, and neuroborreliosis. Previous research has demonstrated that breast cancer tissues could provide an ideal habitat for diverse populations of bacteria, including B. burgdorferi, which is associated with a poor prognosis. Recently, we demonstrated that infection with B. burgdorferi enhances the invasion and migration of triple-negative MDA-MB-231 cells which represent a type of breast tumor with more aggressive cancer traits. In this study, we hypothesized that infection by B. burgdorferi affects the expression of cancer-associated genes to effectuate breast cancer phenotypes. We applied the high-throughput technique of RNA-sequencing on B. burgdorferi-infected MDA-MB-231 breast cancer and normal-like MCF10A cells to determine the most differentially expressed genes (DEG) upon infection. Overall, 142 DEGs were identified between uninfected and infected samples in MDA-MB-231 while 95 DEGs were found in MCF10A cells. A major trend of the upregulation of C-X-C and C-C motif chemokine family members as well as genes and pathways was associated with infection, inflammation, and cancer. These genes could serve as potential biomarkers for pathogen-related tumorigenesis and cancer progression which could lead to new therapeutic opportunities.
Análise comparada da mortalidade materna e seus determinantes distais no Brasil e no México
Authors: BARROS SIMONE REGINA ALVES DE FREITAS , LIMA ANACÁSSIA FONSECA , CAVALCANTE JESIMIEL PINHEIRO , SILVA ADRIANA THIARA DE OLIVEIRA , RODRIGUES DIEGO DE FREITAS 
Published: October 2023

Introdução: A Mortalidade Materna é definida como um fenômeno de saúde pública, é um indicador direto do desenvolvimento de um país, dado que reflete o estado de saúde da população e é um indicador de justiça, equidade e desenvolvimento social, além de ter um caráter trágico e evitável. O presente trabalho visa comparar a Mortalidade Materna no Brasil e México. Materiais e Métodos: Utilizou o método comparativo tendo como finalidade principal a descrição das relações entre variáveis a partir de hipóteses especulativas. Resultados: Os resultados demonstram que a variável Índice de Desenvolvido Humano tem uma forte correlação com a variável dependente Mortalidade Materna, demonstrando que 82,2% da variabilidade da mortalidade pode ser descrita (ou explicada) pela variabilidade do Índice de Desenvolvimento Humano. Já a variável Gini apresentou uma moderada correlação com a Mortalidade Materna, porém não apresentou significância ao modelo. Discussão: Embora perceba-se o progresso na redução da Mortalidade Materna no Brasil e México no período estudado (2006-2016), ainda há elevada carga contínua para os padrões de desenvolvimento socioeconômico, sendo necessários maiores investimentos em políticas públicas que favoreçam a atividade econômica para o gênero.
Análise da estratégia adotada pelo Ministério da Saúde do Brasil na avaliação da qualidade metodológica dos estudos científicos sobre a COVID-19.
Authors: Ferreira Dos Santos Martins Aiane Hirraela , Peduti Graziela Parente , Silva Iasmin de Souza , Diniz Michely Correia 
Published: October 2023

Introdução: O Ministério da Saúde (MS) do Brasil analisou a qualidade metodológica de artigos científicos relacionados à COVID-19. Objetivo: Este trabalho teve como objetivo apresentar e discutir a qualidade metodológica dos estudos selecionados pelo MS baseados em índices já validados na literatura científica internacional. Material e Métodos: Foram analisados quanti-qualitativamente 100 informes, de abril a agosto de 2020, que tinham 08 categorias de trabalhos: Estudos de revisão, coorte, Ensaios clínicos, casos controle, estudos transversais, relatos/série de casos, opinião e protocolos. Resultados: Os resultados mostraram 2.621 estudos publicados no Informe diário de evidência/COVID-19, com 1.497 (57,1%) trabalhos qualificados de acordo com as ferramentas internacionais sendo elas: JBI, AMSTAR e Cochrane. A qualidade metodológica foi analisada como 41% não identificável, 24% boa, 16% moderada, 14% baixa, 5% alta e 1% ruim. Discussão: São necessárias novas ferramentas para análises de outros tipos de trabalhos, como por exemplo, os in silico, in vitro ou trabalhos narrativos, que facilitem o conhecimento e a abordagem investigativa. Conclusão: O uso de ferramentas de avaliação crítica de qualidade metodológica mostrou ser uma estratégia fundamental para indicar a confiabilidade de cada estudo.
El nacimiento de la Biblioteca Histórica “Roger Guerra García”
Authors: Aponte Castro Rocío Del Pilar , Ochoa Álvarez Wendy 
Published: October 2023

El presente artículo expone un recuento del proceso de adecuación de un espacio que resguarda la historia de la Universidad Peruana Cayetano Heredia (UPCH) a través de un importante acervo bibliográfico y documental: la Biblioteca Histórica. El objetivo de este artículo es narrar las acciones que llevaron a la construcción de este espacio y su proceso de transformación en un centro de información y de promoción cultural. De igual forma, se describen los últimos hallazgos de relevancia histórica que se han realizado, y los servicios que se están implementando con el fin de visibilizar el patrimonio y legado cultural de la UPCH.
Investigation into the Multistage Mechanical Damage Behavior of Columnar Jointed Basalts with Different Meso-Constitutive Relations and Model Sizes
Authors: Wang Yongyi , Gong Bin , Yang Xiaoyu , Tang Chun’an 
Published: October 2023

AbstractThe mechanical characteristics of columnar jointed basalts (CJBs) are generally considered to be subject to size effects. They display complex mechanical behaviors under lateral pressure, which may be related to the variation in the rock's mesoproperties. In this study, many nonuniform CJB models with various rock meso-constitutive relations and model sizes were established, and their influences on the strength and deformation properties, multistage mechanical damage behavior, and acoustic emission characteristics of CJBs were investigated. The results show that, as the residual strength coefficient increases, the compressive strength of CJBs rises, and the equivalent deformation modulus of CJBs decreases or increases slightly; with an increase in the model size, the compressive strength slightly decreases at first and then varies moderately, and the equivalent deformation modulus shows a fluctuating trend. Furthermore, the macro stress–strain relationships can be divided into different stages according to the corresponding damage behaviors. The strains and energy accumulations before peak stress was reached were further analyzed. The results greatly improve our understanding of the collapse process of CJBs and the instability precursors of related structures.
Biostratigraphy, Lithology and Geochemistry of the Lower and Middle Cambrian Rocks in the Kyulenke River Basin: First Results of Borehole Core Study
Authors: Korovnikov I.V. , Varaksina I.V. , Kontorovich A.E. , Parfenova T.M. 
Published: October 2023

Abstract
—We have studied biostratigraphy, lithology and geochemistry of drill cores from the Kyulenke River basin. The study of fossil remains and rock compositions, the analysis of trilobite distributions and changes in the lithological and geochemical characteristics of the sediments made it possible to identify structural features of the marker horizons, to correlate borehole sections and outcrops, to compare individual Cambrian intervals and the regional zones of the Yudoma–Olenek facies region of the Siberian Platform. The study has shown rocks of the Kuonamka Fomation to be enriched in uranium (U) and revealed a direct relationship between the contents of U and organic carbon (Corg) in the analyzed rocks, typical for the lower and middle Cambrian black shale deposits sampled from the outcrops in the eastern parts of the Siberian Platform. For the first time, a relationship of rock radioactivity by gamma-ray logging with the contents of U and Corg in Cambrian rocks was established.
Insights from a 3-Year Genomic Evolution of SARS-CoV-2 Shows a Predominance of Variants from Developing Countries
Authors: Abdelmounim ESSABBAR , Safae EL MAZOURI , Azeddine IBRAHIMI 
Published: October 2023

Abstract
Introduction: In nearly 3 years of circulation among the human population, SARS-CoV-2 underwent a complex evolution, shaping its genetics and adaptation to humans. Our study highlights varying prevalence, distribution across regions, and pandemic timeline.
Methodology: In this study we used a dataset of 14,759 SARS-CoV-2 genomes collected between December 2019 and January 2023 from 214 countries. The sequences were analyzed comparatively to explore how SARS-CoV-2 variant mutation patterns varied across time and geographic locations.
Results: We identified a total of 801 lineages harboring 17,360 nucleic mutations, with an average annual evolution rate of 26.07 substitutions per sample. The lifespan of these variants significantly shortened over time, as dominant virus strains were successively replaced by more adapted variants. SARS-CoV-2 variants' lifespan notably decreased as the pandemic progressed. Dominant virus strains were replaced by more fit variants carrying mutations associated with neutralizing antibodies and potential immune escape. Importantly, we identified a significant proportion of new SARS-CoV-2 variants emerging from developing countries, particularly in sub-Saharan Africa, South America, and South Asia, in spite of the overall homogenization of the SARS-CoV-2 genomic landscape since January 2021.
Conclusions: Our analysis underscores the dynamic evolution of SARS-CoV-2, with variants rapidly emerging, adapting, and spreading globally, particularly from specific geographic regions of the world which shaped the course of the pandemic.
Direct regeneration and morpho-histological study of de novo shoot development from leaf explants of Rhododendron mucronulatum Turcz.
Authors: Zaytseva Yulianna 
Published: October 2023

Abstract

Rhododendron mucronulatum Turcz., a rare medicinal and ornamental deciduous multi-branched shrub native to northern parts of East Asia, is a valuable genetic resource for breeding and biotechnological producing bioactive metabolites. To create propagation system of R. mucronulatum, an efficient method of direct shoot regeneration from leaf explants based on thidiazuron (TDZ) and dark treatment was developed, and detailed histological analysis for revealing localization of cell competent to morphogenesis was carried out for the first time. The highest regeneration rate (75%) and number of shoots per explant (an average of 51.7) were achieved under 0.5 µM TDZ and dark treatment. The dark treatment was found to increase the regeneration rate more than two-fold compared to culturing under light conditions. The histological analysis showed direct organogenesis pathway. The competent to morphogenesis cells were located in epidermal tissue of leaf explants on adaxial side of petiole next to main vein. Two sites of beginning of TDZ-induced adventitious shoot formation were revealed: the shoot formation directly from epidermal tissues and shoot formation from de novoepidermis-derived protrusions. The formation of embryo-like structures was observed on the late morphogenesis stages. It was discovered that parenchymal and epidermal tissues of embryo-like structures were separated from explant tissue but its vascular bundle was connected with vascular bundle of explant. These structures gave rise to development of adventitious shoots. The result obtained can promote further establishment of efficient and stable systems for genetic transformation and biomass production of R. mucronulatum.
Field evaluation of a simple and rapid diagnostic test, RLDT to detect Shigella and enterotoxigenic E. coli in Indian children
Authors: Chowdhury Goutam , Ghosh Debjani , Zhou YiYi , Deb Alok K. , Mukhopadhyay Asish Kumar , Dutta Shanta , Chakraborty Subhra 
Published: October 2023

Abstract
The diagnostic assays currently used to detect Shigella spp. (Shigella) and enterotoxigenic Escherichia coli (ETEC) are complex or elaborate which make them difficult to apply in resource poor settings where these diseases are endemic. The simple and rapid nucleic acid amplification-based assay "Rapid LAMP-based Diagnostic Test (RLDT)" was evaluated to detect Shigella spp (Shigella) and enterotoxigenic Escherichia coli (ETEC) and determine the epidemiology of these pathogens in Kolkata, India. Stool samples (n = 405) from children under five years old with diarrhea seeking care at the hospitals were tested, and 85(21%) and 68(17%) by RLDT, 91(23%) and 58(14%) by quantitative PCR (qPCR) and 35(9%) and 15(4%) by culture, were positive for Shigella and ETEC, respectively. The RLDT showed almost perfect agreement with qPCR, Kappa 0.96 and 0.89; sensitivity 93% and 98%; specificity 100% and 97% for Shigella and ETEC, respectively. While RLDT detected 12% more Shigella and 13% more ETEC than culture, all culture positives for Shigella and ETEC except one each were also positive by the RLDT, sensitivity 97% and 93% respectively. RLDT is a simple, sensitive, and rapid assay that could be implemented with minimum training in the endemic regions to strengthen the disease surveillance system and rapid outbreak detection.