bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lower Intelligence Quotient and Larger Brain Volume in the Precuneus among Patients with Graves’ Disease
Authors: Lai Kuan-Yu , Lin Shih-Hsien , Tseng Huai-Hsuan , Lee I Hui , Chen Po See , Chen Kao Chin , Huang Shih-Ming , Yang Yen Kuang 
Published: December 2023

Abstract

Objectives:
Neuropsychiatric symptoms are related to hyperthyroidism. Whether global cognitive function is impaired is unclear. In this study, we intended to investigate whether patients with Graves’ disease (GD) are characterized by a lower intelligence quotient (IQ) and gray matter volume loss.

Methods:
We enrolled 36 patients with GD and 36 healthy controls. Intelligence quotient and other cognitive functions, such as memory and attention, were assessed. Magnetic resonance imaging (MRI) study was used to measure the gray matter volume for those study participants.

Results:
Significantly lower IQ scores (p < 0.001) and poor memory function (p < 0.05) were found among the patients with GD. We also found that patients with GD had a nonsignificant larger gray matter volume in the precuneus compared with that in healthy controls.

Conclusion:
The deficits on global and complex cognitive testing among patients with GD should be noted. We speculate that the larger gray matter volume in the precuneus might be due to compensation.
La estadística, una herramienta indispensable para la investigación en Ciencias de la Salud
Authors: Toledo Margarita Cortés , Álvarez Esteban Moraga , Espinoza Ivette Aguayo , Celis Paula Méndez , Jiménez Diego Silva 
Published: December 2023

Un sistema de salud eficiente y eficaz necesariamente debe estar apoyado por el ejercicio de la investigación en salud a través de una amplia gama de métodos que abarquen todas las dimensiones de la persona y su entorno, con la finalidad de fundamentar con la mejor evidencia disponible las decisiones en salud. Objetivo: Describir las herramientas de la Estadística a través de sus técnicas para dar cuenta de la importancia de esta en la investigación en ciencias de la salud. Metodología: Se realizó una investigación a través de la revisión narrativa, para aproximarse al conocimiento del tema principal, donde fue fundamental la experiencia previa de las y los autores en las áreas de Estadística, Matemática e Investigación en Ciencias de la Salud. Resultados: La Estadística está presente en todo el proceso de investigación desde el muestreo probabilístico, pasando por las medidas descriptivas y gráficos recomendados según la naturaleza de las variables en estudio, utilizando pruebas de hipótesis paramétricas y no paramétricas recomendadas para comparar muestras y relacionar variables. Conclusiones: La Estadística desempeña un papel esencial en la investigación en salud, junto con las herramientas tecnológicas, tienen un impacto significativo en la generación de conocimiento y la toma de decisiones en Ciencias de la Salud, basados en la evidencia científica.
DESAIN ALAT STERILISASI DENGAN SINAR UVC DI MASSA PANDEMI COVID-19
Authors: Sutiari Desak Ketut 
Published: December 2023

Sejak massa pandemi Covid-19 hingga sekarang kebutuhan masyarakat akan sterilisasi untuk menjaga kesehatan terutama untuk menghindari penyebaran virus Corona sangat dibutuhkan. Salah satu sterilisasi yang menjadi pilihan dimasa pandemi adalah sterilisasi kering dengan mengguanakan sinar UVC. Sinar UVC efektif membunuh kuman dan virus dengan pemaparan panjang gelombang tertentu dan waktu tertentu. Sterilisasi dengan menggunakan sinar UVC hanya dapat dilakukan pada benda mati. Dalam pengaplikasiannya perlu sistem timer dan pengaman pintu agar manusia tidak terpapar. Penelitian dilakukan dengan kegiatan perancangan alat dan uji coba alat. Pembuatan sistem terdiri atas sistem mekanik untuk pembuatan lemari dan dilanjutkan dengan pembuatan sistem rangkaian elektronika alat. Penelitian ini menghasilkan lemari sterilisasi dengan bahan dasar kayu berukuran (44 x 30 x 34) cm dilengkapi dua buah lampu UVC 8 Watt. Sebagai pengontrol timer dan limit switch pada pintu lemari digunakan Arduino promini. Hasil pengujian alat, sistem timer bekerja dengan baik dengan rata-rata error sebesar 0,03%.
Effect of Charcoal and Active Carbon as Filter Media on Electrokinetic Remediated Crude Oil-Contaminated Soil
Authors: Adebayo Kabiru , Sani Engbonye John , Musa Abdulrahman , George Moses , Olumide Oluwasanmi Ige 
Published: December 2023

Research has shown that traditional electrokinetic remediation (EKR) technology has limited efficiency against different contaminants and soils. This has led to the use of several strategies to enhance the traditional EKR for higher contaminants removal efficiency. This paper separately uses charcoal and active carbon (AC) each 1 cm thick as filter media in EKR to enhance the removal of crude oil from crude oil-contaminated soil (COCS) containing 78,600 mg/kg of crude oil. The filters are placed very close to the anode compartment containing 0.01 M NaOH electrolytes. Graphite electrodes are used in a face-to-face configuration to pass 1 V DC/cm through the COCS. Crude oil removal efficiencies of 81.4% and 84.6%, respectively, are obtained from the EKR setups containing charcoal and AC filters after 18 and 14 days of remediation, respectively. This makes AC a better filter medium than charcoal for COCS. The results of the chemical oxides compositions show improvement from non-lateritic COCS to lateritic for the filter media-enhanced EKR soil, although AC has proven to be a better filter medium compared to charcoal for use in enhancing EKR technology for COCS. Nonetheless, with over 80% removal efficiency, charcoal or AC filters can be used to enhance EKR remediation of COCS.

Received: 3 November 2023 | Revised: 30 November 2023 | Accepted: 8 December 2023

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
The data that support the findings of this study are openly available at https://doi.org/10.4314/njt.v42i2.3.

Author Contribution Statement
Kabiru Adebayo: Conceptualization, Methodology, Validation, Formal analysis, Investigation, Resources, Data curation, Writing - original draft, Writing - review & editing, Visualization, Project administration, Funding acquisition; John Sani Engbonye: Conceptualization, Methodology, Investigation, Writing - review & editing, Supervision; Abdulrahman Musa: Resources; Moses George: Conceptualization, Methodology, Investigation, Writing - review & editing, Visualization, Supervision; Ige Olumide Oluwasanmi: Investigation, Supervision.
Leprosy spread in urban area: part I: epidemiological characteristics of an endemic urban area for leprosy: the county of São Gonçalo, Rio de Janeiro state, Brazil
Authors: ANDRADE Vera L.G. , SABROZA Paulo Chagastelles , CASTROS Antonia J. Werneck de , MOTTA Célio Paula 
Published: December 2023

Among the needs of deepening the epidemiological inquiry studies of leprosy diffusion in urban area, the evaluation of the Local Information System stands out as base instrument to carry out an epidemiological and operational analysis. The information system was utilized also as base to the populational planning studies. In the present paper, the achievement of the recorded cases mapping in three sanitary units in respective copyhold sectors, as well as the analysis of the specific epidemiological and operational indicators, permited the characterization of the São Gonçalo county as urban endemic area for leprosy, the delimitation of the foci and the inquiry planning. Starting with the specific indicators, according to age, sex, clinical form in the case register date, it was verified a higher detection rate in women than in men, as well as an increase of the tendency of the tuberculoid forms. In the epidemiological inquiry conducted during 85 days, 926 dwellings were visited with interview, physical examination, anthropometric measurings and soluble antigen (SA) application. Such inquiry was conducted by a staff of health professionals and specially trainned and standardized community members. The produced results confirmed that in the copyhold sectors without registered cases, no case, was found and that the domiciliary visits during the Sunday do not presented a superior productivity to the allover days of the week. The whole of the findings lead oneself to conclude that the Local Information System is a valuable instrument for the description of the endemic characteristics in this county and file a construction adequate to the planning of populational studies.
Pemberdayaan Ekonomi Perempuan di Majlis Ta’lim Yasin Fadhilah Karang Rejo Metro Utara Kota Metro
Authors: Ali Muhammad , Susilawati Ani , Binhas Qois Azizah , Eka Priyantoro Dian , Wahyudi Dedi , Khotijah Khotijah 
Published: December 2023

This research examines about women's economic empowerment at majlis ta'lim Yasin Fadhilah Karang Rejo Metro Utara Metro city. Community empowerment efforts can be done in three ways, namely by strengthening their human resources, protecting the community, and defending weak communities. The purpose of this empowerment is carried out for assistance as well as guidance to the community especially in majlis talim Yasin Fadhilah Karang Rejo North Metro Metro City related to women's economic development. women's economic development. Through home industry small business units have been developed such as making tempeh chips, making cakes, and geribik. In running a business, of course, there are many obstacles faced such as declining selling power due to difficulties in marketing products in the market. in the market. The method used in this research is Participatory Action Research PAR. The results showed that the decline in competitiveness due to weakness in marketing products.
Keywords: Economic Empowerment of Women, Economic Empowerment, Assistance Economic Empowerment
PENERAPAN MODEL PEMBELAJARAN PROBLEM BASED LEARNING (PBL) DALAM UPAYA MENINGKATKAN KEMAMPUAN BERPIKIR KREATIF SISWA MAN 3 JOMBANG
Authors: DHANI ARINI RAHMA 
Published: December 2023

Weak ability of students' creative thinking skills towards learning in Biology Education is shown by the lack of interactive learning and lack of creativity in giving examples of solutions to learning materials learning material. Students' creative thinking skills can be improved through application of problem-based learning model learning (PBL) model. This research aims to determine the existence of an increase in the creative thinking ability of students in class X MAN 3 Jombang through the problem-based learning model. based learning (PBL) learning model. Method method used in this research is class action research (PTK) with 2 cycles. cycle. The sample in this study were students of class X-7 MAN 3 Jombang City with a total of 40 people. The research instruments used were observation sheets, questionnaire sheets, written tests, and documentation. This research procedure uses quantitative descriptive data analysis. Based on the results of the study showed that creative thinking skills in cycle I amounted to 77.25% and cycle II amounted to 85.87%, an increase of 8.62%. This shows that the creative thinking skills of students in class X-7 MAN 3 Jombang City increased due to the application of the problem-based learning (PBL) model.
ABSTRAKLemahnya kemampuan berpikir kreatif mahasiswa terhadap pembelajaran pada mata pelajaran Biologi ditunjukan dengan kurangnya interaktif saat pembelajaran serta kurangnya kreatif dalam memberi contoh-contoh penyelesaian terhadap materi pembelajaran. Kemampuan berpikir kreatif mahasiswa dapat ditingkatkan melalui penerapan model pembelajaran problem based learning (PBL). Penelitian ini bertujuan untuk mengetahui adanya peningkatan kemampuan berpikir kreatif siswa kelas X MAN 3 Jombang melalui model pembelajaran problem based learning (PBL). Metode penelitian yang digunakan dalam penelitian ini adalah penelitian tindakan kelas (PTK) dengan 2 siklus. Sampel pada penelitian ini adalah siswa kelas X-7 MAN 3 Kota Jombang dengan jumlah 40 orang. Instrumen penelitian yang digunakan berupa lembar observasi, lembar kuisioner, tes tertulis, dan dokumentasi. Prosedur penelitian ini menggunakan analisis data deskriptif kuantitatif. Berdasarkan Hasil penelitian menunjukkan bahwa keterampilan berpikir kreatif pada siklus I sebesar 77.25% dan siklus II sebesar 85.87% maka peningkatan sebesar 8,62%. Hal ini menunjukkan bahwa kemampuan berpikir kreatif mahasiswa siswa kelas X-7 MAN 3 Kota Jombang meningkat karena penerapan model pembelajaran problem based learning (PBL).
A INCLUSÃO DE MULHERES NO CAMPO DE ESTÁGIO: PROTAGONISMO FEMININO EM FOCO
Authors: Silva Joelma Paz da , Aride Paulo Henrique Rocha 
Published: December 2023

A pesquisa analisa aspectos que caracterizam as dificuldades na inclusão ao mundo do trabalho no campo da formação profissional, no qual destacamos a importância por meio do estágio. Sendo em alguns casos os primeiros contatos com a experiência profissional, iniciando os desafios em ingressar em uma área técnica. Assim, a pesquisa vem na desconstrução dessas desigualdades que tomam proporção quando o assunto se refere ao acesso de mulheres na área técnica, nos levando a pensar e sustentar um estudo que integrasse a formação técnica, o gênero, o estágio e o mundo do trabalho como uma construção ontológica-histórica ao longo do tempo. Desta forma, lançamos o seguinte problema científico: Existe influência do fator gênero na inclusão para o estágio curricular do curso de Mecânica da Educação Profissional Técnica de Nível Médio na modalidade subsequente do CMC? Explicamos que os cursos subsequentes são cursos com a modalidade oferecidos a estudantes que concluíram o ensino médio. Tem como objetivo geral: Compreender os processos de inclusão e participação de mulheres no curso de Mecânica da Educação Profissional Técnica de Nível Médio na modalidade subsequente. Traçamos três objetivos específicos: 1) Compreender as relações e processos que envolvem discussões sobre o gênero na inclusão ao estágio profissional; 2) Identificar as dificuldades enfrentadas pelas estudantes finalistas no processo de inclusão ao mundo trabalho; 3) Descrever as barreiras sociais que dificultam a participação no ingresso das estudantes no mundo do trabalho por meio do estágio profissional. O método usado na pesquisa foi o estudo de caso único. Realizamos uma abordagem qualitativa, envolvendo as mulheres, egressos, professores, técnicos administrativos e agente de integração de estágios, que possibilitou entrevistas prolongadas e rodas de conversas com as turmas finalistas, que aplicamos como instrumento na coleta dos dados com a análise dos resultados, conduzida por meio da Análise de Conteúdo.
Espacio, cuerpo y afecto en Casas vacías de Brenda Navarro
Authors: Gaffurri Oldano Cesare 
Published: December 2023

El siguiente artículo propone un entramado teórico-crítico a partir las nociones de espacio, cuerpo y afecto para analizar la novela Casas vacías de la escritora mexicana Brenda Navarro, respecto a las reflexiones que se dan al interior de la historia tales como la maternidad, la extranjería, la identidad y la memoria. Tal entramado podrá servir para proponer la noción del locus affectus para comprender de qué manera el cuerpo puede ser entendido como un espacio, una superficie intensiva.
Tales consideraciones tienen como punto de partida comprender la relación del cuerpo y el afecto desde la forma de la novela, para comenzar a poner en discusión algunas teorías sobre el espacio, el cuerpo y los afectos, principalmente a través de pensadores como Mabel Moraña, Meri Torras, Paul Ricoeur y José Valles Calatrava. De esta manera, se podrán identificar tales nociones de la novela, principalmente en cuestiones relacionadas a la maternidad y el maternar, y la forma en cómo el cuerpo femenino se vincula con el otro.
The Effect of Body Mass Index on the KYN/TRP Pathway in the Pathogenesis of Periodontitis
Authors: GÜNEY Zeliha , ALTINGÖZ Sema Merve 
Published: December 2023

ABSTRACT
Purpose: The tryptophan–kynurenine (TRP-KYN) pathway is associated with inflammation and kynurenine pathway (KP) dysregulation is present in overweight and obesity. Meanwhile, obesity and periodontitis are two of the most frequent noncommunicable illnesses, and epidemiological studies show that obesity has a role in the initiation and progression of periodontitis. However, the association between elevated body mass index and KP on periodontal disease etiology is unknown. As a result, our study is aimed to investigate the possible relationship within TRP/KYN ratio and BMI relationship in periodontitis.
Materials & Method: The study comprised 20 periodontitis patients (P, Generalized Stage III Grade B, n=20) and 20 healthy persons (C, n=20). Clinical parameters (Bleeding index on probing (BOP), clinical attachment loss (CAL) and pocket depth (PD)), and BMI were recorded at the beginning of the study. Salivary and serum KYN/TRP ratios were analyzed by using mass spectrometry–liquid chromatography (LC-MS/MS).
Results: Clinical periodontal parameters were statistically significantly higher in P group than in C group (p
Doppler transcraneal y su impacto en el pronóstico de la lesión cerebral traumática, Hospital Clínico Viedma, Cochabamba-Bolivia.
Authors: Huanca Cristhian , Espinoza Marquéz Alejandra Natalia , Ortega Martinez Rommer Alex 
Published: December 2023

Introducción: La lesión cerebral traumática (LCT) es una causa importante de muerte y discapacidad; predecir el resultado, es de utilidad en la toma de decisiones. El doppler transcraneal (DTC), es una herramienta diagnóstica y monitorización del flujo sanguineo cerebral; podría establecer un pronóstico confiable y temprano. El objetivo es evaluar sí las características del DTC es eficaz como indicador pronóstico. Material y métodos: Se realizó un estudio prospectivo de pacientes con LCT. Se efectuaron mediciones con DTC al ingreso y su estadía; el índice de pulsatilidad se calculó́ mediante la fórmula de velocidad sistólica y diastólica, dividida con la velocidad media (VS-VD/VM); se consideró hipertensión endocraneana si el índice de pulsatilidad (IP>1,2); el resultado se evaluó por el puntaje GOSE (Glasgow Outcome Scale Extended) a los 3 meses (información obtenida vía telefónica), dicotomizada: Favorable (4-5) y desfavorable (1-3). Resultados: Fueron incluidos 49 pacientes; el resultado desfavorable a los 3 meses fue del 63,2 %; el análisis del grupo con DTC anormal tiene la probabilidad de presentar 54 veces más de una evolución desfavorable (RR: 54; IC 95 % (8,8-32,8); p<0.0005); Sensibilidad 78 %; especificidad 81%; AUC 0,850, y menor probabilidad de sobrevida a los 14 días (p=0,021); variables independientes asociadas: Escala de coma Glasgow (ECG) cercano a 3 puntos RR: 33; IC 95 % (1,31-10,6); hipotensión RR: 9,28; IC 95 % (1,49-5,7); craniectomía RR: 1,96; IC 95 % (1,01-4,41); pupilas fijas RR: 3,4; IC 95 % (1,15-9,9); Escala de Marshall en conjunción con la ECG mayor sensibilidad y especificidad. Conclusión: Estos datos mostraron una posible eficacia del DTC como herramienta diagnóstica y además pronóstica en la lesión cerebral traumática.
Palabras Clave: Lesiones traumáticas del encéfalo, pronóstico, presión intracraneal, ultrasinografia doppler trasncraneal.
ŞİZOFRENİ TANILI HASTALARDA D VİTAMİNİ DÜZEYLERİNİN PSİKOTİK VE DEPRESİF BELİRTİLERLE İLİŞKİSİNİN İNCELENMESİ
Authors: BALTACIOĞLU Mehmet , PUŞUROĞLU Meltem , BAHCECİ Bulent , HOCAOGLU Cicek , HELVACI ÇELİK Fatma Gül 
Published: December 2023

Amaç: Şizofreni pozitif, negatif, afektif ve bilişsel belirtilerle karakterize nörogelişimsel bir bozukluktur. Şizofrenide etiyolojiyi aydınlatmaya yönelik çok sayıda çalışma yapılmıştır. Son dönem çalışmalar D vitamini [(25(OH)D] düzeyleri ve şizofreni ilişkisine odaklanmıştır. Bu çalışmada D vitamini düzeyleri ile şizofreni hastalarındaki semptom şiddeti ilişkisinin araştırılması amaçlandı.
Gereç ve Yöntem: Çalışmaya Rize Devlet Hastanesi Toplum Ruh Sağlığı Merkezine kayıtlı toplam 93 hasta dahil edildi. Katılımcıların D vitamini düzeylerini tespit etmek için dolaşımda en yüksek konsantrasyonda bulunan 25(OH)D vitamini formu kullanıldı. Tespit edilen D vitamini değerleri Negatif Belirtileri Değerlendirme Ölçeği (SANS), Pozitif Belirtileri Değerlendirme Ölçeği (SAPS), Calgary Depresyon Ölçeği (CDÖ) ortalama puanları ve sosyodemografik verilerle karşılaştırıldı.
Bulgular: Çalışmamızda şizofreni hastalarının yaklaşık %61,3’ünde optimal seviyelerin altında D vitamin düzeyleri saptandı. Katılımcıların % 23,7’ sinde D vitamini eksikliği, %37,6’ sında D vitamini yetersizliği vardı. Ortalama ölçek puanlarının D vitamini düzeyleri ile ilişkisine bakıldığında SANS ve SAPS ölçek puanları ile D vitamini düzeyleri arasında anlamlı ilişki tespit edilmedi. CDÖ ölçeği puanları ile D vitamini düzeyleri arasında ise istatistiksel açıdan anlamlı ilişki saptandı. D vitamini eksikliği olan grupta CDÖ puanları diğer gruplara göre anlamlı derecede yüksekti (p: 0.001).
Sonuç: Çalışmamızda şizofreni hastalarının büyük bir çoğunluğunda optimal seviyelerin altında D vitamini düzeyleri saptandı. Tespit edilen düşük D vitamini düzeylerinin de depresif belirtilerle ilişkili olduğu gözlendi.
Dynamic Scheduling for Large-Scale Flexible Job Shop Based on Noisy DDQN
Authors: Zheng Tingjuan , Zhou Yongbing , Hu Mingzhu , Zhang Jian 
Published: December 2023

Article
Dynamic Scheduling for Large-Scale Flexible Job Shop Based on Noisy DDQN

Tingjuan Zheng 1,2, Yongbing Zhou 1, Mingzhu Hu 1, and Jian Zhang 1,*

1 Institute of Advanced Design and Manufacturing, School of Mechanical Engineering Southwest Jiaotong University, Chengdu 610031, China
2 Guizhou Aerospace Electric Co., Ltd., Guiyang 550009, China
* Correspondence: Jerrysmail@263.net

Received: 3 July 2023
Accepted: 8 October 2023
Published: 21 December 2023

Abstract: The large-scale flexible job shop dynamic scheduling problem (LSFJSDSP) has a more complex solution space than the original job shop problem because of the increase in the number of jobs and machines, which makes the traditional solution algorithm unable to meet the actual production requirements in terms of the solution quality and time. To address this problem, we develop a dynamic scheduling model of a large-scale flexible job shop based on noisynet-double deep Q-networks (N-DDQNs), which takes the minimum expected completion time as the optimization objective and thoroughly takes into account the two dynamic factors (the new job arrival and the stochastic processing time). Firstly, a Markov decision process model is constructed for dynamic scheduling of a large-scale flexible workshop, and the corresponding reasonable state space, action space and reward function are designed. To address the problems (of solution stability and unsatisfactory scheduling strategy selection) in the conventional exploration method of DDQNs, learnable noise parameters are added to the DDQNs to create the N-DDQN algorithm framework, where the uncertainty weight is added. Secondly, the learnable noise parameters are added to the DDQNs to form the N-DDQN algorithm framework, and the uncertainty weight is added to realize automatic exploration. Hence, the issue is solved that the traditional DDQN exploration method may result in unsatisfactory solution stability and scheduling strategy selection. The proposed method, which has significant flexibility and efficacy, is demonstrated (by experimental findings) to be superior to the conventional method based on compound scheduling rules in tackling large-scale flexible job shop dynamic scheduling problems.