bluuebunny/crossref_metadata_2025_split huggingface dataset:
REVITALISASI HOTEL TUGU SEBAGAI BUTIK HOTEL
Authors: Sugiantoro Revi , Utami Wahyu 
Published: November 2023

Setiap bangunan yang sudah ditetapkan sebagai cagar budaya sesuai dengan Undang-Undang RI No 11 Tahun 2010 tentang cagar budaya selalu mempunyai nilai penting sehingga perlu dilestarikan. Namun pada kenyataannya, tidak sedikit bangunan yang sudah ditetapkan sebagai cagar budaya terbengkalai tidak terlestari dengan optimal, salah satunya yaitu Bangunan eks Hotel Toegoe yang berada di Kota Yogyakarta, seberang Stasiun Tugu. Sementara di satu sisi, dalam perundang-undangan telah disebutkan adanya kewajiban pada bangunan cagar budaya memuat amanah untuk memanfaatkan dan mengembangkannya sesuai aturan yang berlaku. Oleh karena itu, dalam tulisan ini akan digambarkan metode alternatif pemanfaatan dan pengembangan Bangunan Eks Hotel Toegoe dengan tapak disisinya untuk dikembangkan sebagai hotel butik. Pemilihan fungsi tersebut tidak bisa dilepaskan dari posisi bangunan yang berdekatan dengan Stasiun Tugu, Kawasan Malioboro, berada di sumbu imajiner dan juga berada di pusat kota. Posisi strategis tersebut menjadi pertimbangan pengembangan desain butik dengan keistimewaan pada interior bangunan eks Hotel Toegoe dan bangunan barunya. Untuk mendukung fungsi tersebut, dalam tahapan desain yang menggunakan Metode lima langkahnya Mc Ginty dengan pendekatan Olah Desain Arsitektur Pusaka (ODAP) serta EBD (Evidence Based Design), maka tahapan yang dilakukan selain menjalani tahapan permulaan dengan memahami status cagar budaya dan fungsi saat ini, persiapan dengan mengeksplorasi data sejarah dan eksisting bangunan serta kawasannya, yang dilanjutkan dengan memberikan alternatif (pengajuan usul) solusi pemanfaatan dan pengembangan yang dilanjutkan dengan eksekusi alternatif desain, serta selalu mengevaluasi alternatif desain dengan berbagai teori dan peraturan cagar budaya dan diakhiri pada desain terpilih. Untuk menunjang tahapan tersebut, melalui pendekatan ODAP dan EBD yang mengkaji tentang alternatif olah desain atau pengembangan dengan berdasarkan bukti-bukti yang menyatakan bahwa bangunan tersebut layak untuk diolah untuk memperkuat dan minimal menjaga nilai-nilai penting bangunan yang terlihat dari bentuk/gaya arsitektur dan nilai penting lainnya. Sementara itu, pertimbangan POE (Post Ecupation Evaluation) digunakan untuk lebih menjelaskan fungsi yang tidak digunakan saat ini. Penerapan metode tersebut diharapkan mampu menjadi pertimbangan dalam pemanfaatan dan pengembangan bangunan cagar budaya sesuai peraturan perundang-undangan dan teori pelestarian. Olah Desain Arsitektur Pusaka (ODAP) dapat menjadi solusi untuk merancang dengan penerapannya metode adaptasi agar tidak merusak bangunan Eks Hotel Toegoe.
Relationship of Age and Parity with Preeclampsia in Pregnant Women at Regional Technical Implementation Unit Robatal Public Health Center in 2022
Authors: Bahtiar Ilham 
Published: November 2023

Background: Indonesia's maternal mortality rate is the second highest in Southeast Asia after Laos in 2015. Preeclampsy itself is a direct cause of maternal death with multisystem disorders that usually affect 2% - 5% of pregnant women in Indonesia. Objective: Determine the relationship between maternal age and parity on the incidence of preeclampsia. Method: What is used in this study is an observational study that is analytical in nature with a cross sectional design or approach. The population in this study is all pregnant women of more than 20 weeks gestation in the Regional Technical Implementation Unit of the Robatal Public Health Centerin 2022, with a total sample of 258 people. Sampling technique using Systematic Random Sampling. The statistical test used is the chi square test. Results: Based on analysis with chi-square test, it was concluded that there was a significant association between age and severe preeclampsia (p=0.031 <0.05) and no significant association between parity and severe preeclampsia (p=0.497>0.05). Conclusions: Based on analysis with chi-square test, it was concluded that there was a significant association between age and severe preeclampsia and no significant association between parity and severe preeclampsia.
The Relationship of Anxiety Level with Sugar Levels Blood in People with Diabetes Mellitus Type 2 at Technical Implementation Unit of Melak Public Health Center
Authors: Oktavianur Taufik 
Published: November 2023

Introduction: Indonesia is ranked 7th in the world with 10.7 million people with diabetes. If this disease is not controlled properly, it will result in an increase in blood glucose levels (hyperglycemia) which can cause various complications, namely metabolic complications, microvascular complications, neuropathy complications and macrovascular complications. Objective: To determine the relationship between anxiety levels and blood sugar levels in patients with Type 2 Diabetes Mellitus at Technical Implementation Unit of Melak Public Health Center. Methods: The research design in this study was descriptive correlation using a cross-sectional approach. Determination of the sample using purposive sampling, with a sample of 56 respondents. Result and Discussion: The level of anxiety in the Technical Implementation Unit of Melak Public Health Center is in the high category (51.8%). Fasting blood sugar levels at Technical Implementation Unit of Melak Public Health Center in the high category (57.1%). The relationship between anxiety levels and blood sugar levels obtained p-value = 0.01 smaller than 0.05 then Ha is accepted and H0 is rejected, meaning that there is a relationship between anxiety levels and blood sugar levels in patients with Type 2 Diabetes Mellitus. Conclusion: There is a relationship between anxiety levels and blood sugar levels in patients with Type 2 Diabetes Mellitus at Technical Implementation Unit of Melak Public Health Center.
Factors Influencing UCI (Universal Child Immunization) Achievement in the Working Area of Technical Implementation Unit Melak Public Health Center
Authors: Trisnawaty Mira 
Published: November 2023

Introduction: The immunization program is part of the ways for the government in prevention and breaking the spread of diseases. The target of UCI (Universal Child Immunization) at Technical Implementation Unit of Melak Public Health Center has not reached it, which is 50% in comparison to the target, 90%. Objectives: This research aims to describe the factors that contributed to the target of UCI (Universal Child Immunization) at the work area of Technical Implementation Unit of Melak Public Health Center. Method: This research was done by using an analytical observational approach of cross sectional. The sampling was non probability sampling, which was a technique that did not give the same equal chance or opportunity to the population that became a sample. Result and Discussion: There was no cause on education (?=0,76) and occupation (?=0,58) to the target of UCI (Universal Child Immunization). But there were causes on knowledge (?=0,001), behavior (?=0,02), family support (?=0,001) and medical workers support (?=0,027) for the target of UCI (Universal Child Immunization) in the work area of Technical Implementation Unit of Melak Public Health Center. Conclusion: Based on the result, it is highly recommended for Technical Implementation Unit of Melak Public Health Center to increase their communication with people about immunization, side effects, kinds of immunizations that are conducted and the contents of immunizations
Symmetric Fano Profiles of Two-photon Electronic Transitions Observed in an Ultracold Rydberg Gas
Authors: Han Jianing , Provencher Brianna , Mitchell Juliet , Steade Chandler , Gong Na , Wang Jinhui 
Published: November 2023

Fano profiles are caused by the interference between the discrete states and continuum. It is a very common phenomenon
in multi-electron Rydberg states, such as the Rydberg states of group II elements in the periodic table. It often leads to
autoionization due to the fact that a discrete state couples with an autoionizing state. Unlike the typical asymmetric line
shape, here we report a symmetric unusual Fano line shape that has been predicted. In addition, this profile is caused
by molecular states or polymer states instead of multi-electron atomic states. Moreover, it is shown that the fano profile
caused by the multi-electron polymer states does not necessarily lead to autoionization. We propose that the Fano profile
studied is caused by the interference between discrete levels and the multipole-multipole coupled continuum, or energy
band.
Gaya Belajar Siswa Kelas XI IPA SMA N 1 Dramaga Bogor Sebelum Pandemi dan Saat Pandemi
Authors: Widyasari Fitri 
Published: November 2023

Berdasarkan penelitian diatas dapat peneliti simpulkan bahwa siswa/i kelas XI IPA 1 SMAN 1 DRAMAGA cenderung memiliki gaya belajar audio pada proses pembelajaran, baik sebelum pandemi dan saat pandemi dikarenakan mereka lebih memahami materi ketika mendengarkan penjelasan dari guru. Namun, proses pembelajaran saat pandemi dengan memberikan penjelasan saja tidak cukup efektif. Hal ini disebabkan oleh situasi dan kondisi masing-masing siswa/i ketika mengikuti proses pembelajaran dari rumah, sehingga dibutuhkan metode dan media pembelajaran yang tepat untuk mendukung proses pembelajaran, baik secara visual, audio visual, dan kinestetik agar siswa/i memiliki minat dalam belajar dan tidak merasa bosan walaupun hanya belajar secara online. Perpindahan proses pembelajaran dari offline ke online ini sangat berpengaruh pada gaya belajar siswa/i. Pada penelitian kami di kelas XI IPA 1 SMAN 1 DRAMAGA sebagian besar dari mereka tidak cocok dengan proses pembelajaran secara online. Dengan demikian, penting sekali guru memahami gaya belajar masing-masing siswa/i dan metode serta media pembelajaran yang tepat agar materi pelajaran dapat tersampaikan dan dipahami oleh siswa/i dengan baik.
Status Unsur Hara Mikro Tanah dan Produksi Berat Kering Alfalfa (Medicago sativa L.) Yang Diberikan Pupuk Bokashi Feses Ayam
Authors: Hambakodu Marselinus , Retang Nikodemus Tunga 
Published: November 2023

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pupuk bokashi feses ayam dengan level yang berbeda terhadap status unsur hara mikro tanah dan produksi berat kering pada tanaman alfalfa (Medicago sativa L.). Penelitian dilaksanakan di Laboratorium Lapangan, Uviversitas Kristen Wira Wacana Sumba, Desa Kuta, Kecamatan Kanatang, Kabupaten Sumba Timur. Penelitian menggunakan metode eksperimental dengan rancangan acak lengkap (RAL) 5 perlakuan dan 4 ulangan yakni P0: tanpa pupuk bokashi, P1: pupuk bokashi feses ayam 250 gram/polybag, P2: pupuk bokashi feses ayam 500 gram/polybag, P3: pupuk bokashi feses ayam 750 gram/polybag, P4: pupuk bokashi feses ayam 1.000 gram/polybag. Variabel penelitian yang diamati adalah tembaga (Cu), seng (Zn), besi (Fe), mangan (Mn) dan produksi berat kering tanaman alfalfa (Medicago sativa L.). Hasil penelitian ini menunjukan bahwa pemberian pupuk bokashi kotoran ayam berpengaruh nyata (p<0,05) terhadap produksi berat kering, sedangkan status hara mikro tanah masih dalam kondisi normal dan lebih tinggi pada perlakuan pupuk 1.000 gram/polybag.
POLA KONSUMSI PRODUK HASIL PERIKANAN OLEH MASYARAKAT KABUPATEN LAMONGAN [Consumption Pattern of Fishery Products by Lamongan Regency Communities]
Authors: Munarko Hadi , Sanjaya Yushinta Aristina , Safa Aidha , Wahfi Ahmad , Tri Novian , Wahyu Okky , Qurota Untsa 
Published: November 2023

Penelitian ini bertujuan untuk menganalisis pola konsumsi hasil perikanan masyarakat Kabupaten Lamongan pasca pandemi. Pengumpulan data dilakukan melalui kuesioner secara daring melalui google form. Kabupaten Lamongan dipilih karena secara geografis letaknya berada dekat dengan pesisir pantai utara Laut Jawa. Hasil survei jawaban responden menunjukan bahwa masyarakat Kabupaten Lamongan sudah banyak mengetahui manfaat dari produk perikanan. Namun, tingkat konsumsi ikan di Kabupaten Lamongan terbilang masih cukup rendah, karena ekonomi dan pengetahuan yang masih kurang. Ikan mujair adalah ikan paling banyak diminati di daerah Kabupaten Lamongan. Responden lebih banyak memilih mengkonsumsi produk ikan segar karena alasan higienitas dan menganggap lebih sehat. Namun, ada juga yang memilih produk ikan olahan karena praktis, mudah penyajiannya, harga terjangkau, dan daya simpannya lebih lama
EKSPLORASI KEANEKARAGAMAN MAKROALGA DAN ANALISIS KOMPOSISI KIMIA BERDASARKAN KELIMPAHANNYA DI PERAIRAN WARAMBADI, SUMBA TIMUR [Exploration of Macroalgae Diversity and Analysis of Chemical Composition Based on Abundance in Warambadi Waters, East Sumba]
Authors: Takanjanji Umbu Domu , Meiyasa Firat 
Published: November 2023

Makroalga merupakan sumber hayati yang cukup melimpah di Indonesia termasuk di Kabupaten Sumba Timur. Eksplorasi makroalga telah dilakukan misalnya di perairan Moudolung, Londalima, dan Waijelu, sedangkan di perairan Warambadi belum dilaporkan. Berdasarkan hal tersebut, maka perlu dikaji spesies makroalga yang tersebar di perairan Warambadi dan analisis komposisi kimianya. Metode yang digunakan dalam identifikasi spesies makroalga yang tersebar di perairan Warambadi menggunakan metode transek garis. Selanjutnya, sampel tersebut diuji komposisi kimianya. Data yang dihasilkan kemudian diuji secara deskriptif menggunakan Microsoft excel. Hasil penelitian menunjukkan bahwa spesies yang tersebar di perairan Warambadi menggunakan metode transek adalah Codium sp., Euchema spinossum, Caulerpa lentillifera. Selanjutnya, komposisi kimia Codium sp., Euchema spinossum, Caulerpa lentillifera masing-masing adalah sebagai berikut kadar air sebesar 14,69-20,48%, abu sebesar 14,67-51,90%, lemak sebesar 0,43-5,15%, protein sebesar 12,64-16,06%, karbohidrat sebesar 35,02-66,95%, dan serat kasar sebesar 3,62-6,61%.
Identifikasi Mikroplastik Polyethylene (PE) Menggunakan Digesting Wet Peroxide Oxidation (WPO)
Authors: Fitriandoni Adisty , Dewata Indang 
Published: November 2023

The extraction method using Wet Peroxide Oxidation (WPO) is a digestion method for separating microplastic particles and other organic/inorganic precipitation, with a liquid oxidation process using peroxide and iron salts as catalysts. Polyethylene (PE) is a type of plastic that pollutes the environment due to its high level of use in the packaging sector. The aim of this research is to determine the optimum conditions for the Wet Peroxide Oxidation (WPO) extraction method and obtain an effective method for identifying microplastics. Variations in oven temperature are 70⁰C, 80⁰C, 90⁰C, 100⁰C, and 110⁰C; variations in Fe(II) concentrsation 0.025 M, 0.05 M, 0.075 M, 0.1 M, and 0.125 M; heating temperature variations 30⁰C, 45⁰C, 60⁰C, 75⁰C, and 90⁰C. The research results showed that the optimum oven conditions occurred at a temperature of 90⁰C producing a microplastic mass of 0.5943 grams, the optimum Fe(II) concentration of 0.1M produced a mass of 1.2966 grams, the optimum heating temperature occurred at 60⁰C producing a mass of 0.7128 grams. For samples, characterization using FTIR showed that no new groups were formed after being treated under optimal conditions. Meanwhile, for XRF, no impurity elements were identified after the sample was treated with optimum conditions.
Pelatihan Komputer Dalam Rangka Peningkatan Kompetensi Guru TK Islam Pelita Insan
Authors: Nugroho Agung , Wiyanto Wiyanto , Romli Ikhsan 
Published: November 2023

Kewajiban bagi dosen dalam melaksanakan tridharma perguruan tinggi salah satunya adalah kegiatan pengabdian pada masyarakat. Salah satu bentuk pengabdian pada masyarakat adalah melaksanakan pelatihan kepada elemen masyarakat yaitu guru sekolah pada tingkat dasar. Pelatihan yang dilaksanakan adalah dalam rangka meningkatkan kompetensi Guru TK di sekolah TK Islam Pelita Insan dalam hal penggunaan Teknologi Informasi dan Komputer (TIK) berupa pengoperasian software pengelolaan data perkantoran yaitu Microsoft office.
Kata kunci: Pelatihan komputer, kompetensi guru, Pembelajaran
Pendampingan SMK Merah Putih Menuju SMK BISA-HEBAT
Authors: Zy Ahmad Turmudi , Ekhsan Muhamad , Sasongko Ananto Tri , Nugroho Agung 
Published: November 2023

Pendampingan SMK Merah Putih Menuju SMK BISA-HEBAT adalah sebuah program yang bertujuan untuk meningkatkan kualitas SMK Merah Putih menjadi SMK yang bisa bersaing dan memiliki keunggulan di bidangnya, yaitu SMK BISA-HEBAT. Program ini akan memberikan pendampingan dan bimbingan kepada SMK Merah Putih untuk melakukan perubahan yang diperlukan agar bisa mencapai standar kualitas SMK BISA-HEBAT. Program ini terdiri dari beberapa tahap, antara lain evaluasi awal, identifikasi masalah, penyusunan rencana aksi, pelaksanaan rencana aksi, dan evaluasi akhir. Evaluasi awal bertujuan untuk menilai kondisi SMK Merah Putih saat ini, sedangkan identifikasi masalah akan membantu dalam mengidentifikasi masalah utama yang harus diatasi. Setelah masalah diidentifikasi, dilakukan penyusunan rencana aksi yang akan dijalankan oleh SMK Merah Putih untuk mencapai standar SMK BISA-HEBAT. Pelaksanaan rencana aksi akan dilakukan dengan pendampingan dan bimbingan dari tim pendamping, yang akan membantu SMK Merah Putih dalam mengatasi kendala-kendala yang muncul selama pelaksanaan. Terakhir, evaluasi akhir akan dilakukan untuk mengevaluasi hasil dari program ini dan memberikan rekomendasi untuk perbaikan lebih lanjut. Dalam program ini, SMK Merah Putih akan dibimbing dan didampingi oleh tim pendamping yang terdiri dari ahli-ahli di bidangnya, seperti ahli pendidikan, ahli manajemen sekolah, dan ahli bidang industri. Diharapkan dengan adanya program ini, SMK Merah Putih dapat meningkatkan kualitasnya dan menjadi SMK BISA-HEBAT yang dapat bersaing di dunia industry
Kata kunci: Pendampingan, SMK, SMKBISA-HEBAT
Effect on Yield, Attribute Character and Economics of Various Treatment in Wheat (Triticum aestivum L.) Crop
Authors: Kumar Anil , Dwarka  , Nayak Kratika , Kumar Kailash , Kumhare Alpana , Tekam Yagini 
Published: November 2023

A field experiment was conducted at Agronomy Research Farm of Narendra Deva University of Agriculture & Technology, Narendra Nagar (Kumarganj), Faizabad (U.P.) during Rabi season of 2014-15 to study the response of late sown wheat varieties to doses of nitrogen application. Eighteen treatment consisted of six doses of nitrogen (0, 40, 80, 120, 160 and 200 kg N ha-1) and three varieties of wheat (PBW-373, HD-2327, and NW-1014). The experiment was carried out in Randomized Block Design R.B.D. (factorial) with three replications on silt loam having low organic carbon (0.37%), nitrogen (194.25 kg ha-1), medium in phosphorus (15.25 kg ha-1) and potassium (250.25 kg ha-1). All the growth and yield parameters increased significantly with increasing nitrogen doses up to 200 kg ha-1. The maximum net return (Rs. 40712ha-1) was obtained at 160 kg N ha-1 with NW-1014 and B:C ratio 1.19 followed by same variety at 120 kg N ha-1. Thus it may be concluded that application of 160 kg N ha-1 proved appropriate levels of nitrogen for exploration of the yield potential of the late sown wheat varieties. Among the varieties NW-1014 was found the most suitable for cultivation under late sown condition for Northern East Plain zone.
Effect of Bio-Agents and Organics Against Fusarium Wilt of Ashwagandha
Authors: Mishra R. S. , Bahadur Raj 
Published: November 2023

Ashwagandha (Withania somnifera) roots are the major source of alkaloids including tropine, pseudotropine and somniferine. Production of Ashwagandha root is less as compared to other medicinal plants because of wilt disease caused by Fusarium solani. The wilt infected plant has fully disturbed and finally whole plant is wilted. Therefore bio-agents and bio-fumigants (crusiferea plants) were evaluated. All treatments were significantly reduced the disease infection from 13.79 % - 90.8 %, 11.08 % - 72.44 %, 15.36 % - 68.48 % and 14.04 % - 61.44 % at 30, 60, 90 and 120 days after sowing. The per cent disease control was maximum 90.86 % in Trichoderma harzianum @ 2.0 %. The highest plant growth was observed in Trichoderma harzianum such as plant height (42.87 cm), stem length, (39.52 cm) and root length (12.07 cm). Highest seed yield per pot was recorded in T1- Trichoderma harzianum (1.95 g) which was statistically at par with T5 (1.87 g) and T2 (1.65 g).
Serological Evaluation of a Cohort of Patients with Chronic Chagas Disease Treated with Benznidazole in a Low Endemic Area of Central Brazil
Authors: Casé-Leite Alinne R. , Camarço Willian R. , Carvalho-Campos Samuel N. M. , Hofmeister Georges B. , Fontes Cor J. F. , Gomes Luciano T. 
Published: November 2023

Background: The most widely accepted criterion for assessing the cure of chronic Chagas disease after etiological therapy is the negativization of anti-Trypanosoma cruzi antibodies long after the completion of treatment.
Materials and Methods: We employed various serological antibody detection techniques to ascertain whether benznidazole treatment successfully cured chronic Chagas disease in a retrospective cohort of patients in a low-endemic area in central Brazil. Antibodies were assessed using indirect immunofluorescence (IIF) and enzyme immunoassay (ELISA) before treatment and 1-18 years post-treatment. A reevaluation of 89 patients was conducted in 2018, which included indirect hemagglutination (IHA), chemiluminescence (CL), and polymerase chain reaction (PCR) analyses.
Results: Seventeen patients were monitored for 15 years or more, seven for 10-15 years, 50 for 6-10 years, and 17 for 1-5 years. Only two patients who received treatment tested PCR-positive at reevaluation, indicating treatment failure. Both patients discontinued treatment early due to benznidazole's side effects. The incidence of serological test negativization was 10.1%. However, antibody levels determined by ELISA decreased with the increased duration of follow-up (p=0.002). Similarly, antibody titers of IIF-positive sera were lower in post-treatment reevaluations than those in pre-treatment titers, indicating reduced levels of anti-T. cruzi antibodies. These levels decreased in a duration-dependent manner during follow-up.
Conclusion: The results reveal a low cure rate based on antibody negativization, but antibody titers significantly decreased in all conventional serological tests. These findings suggest that decreased antibody levels may be associated with parasitological cure in patients with chronic Chagas disease after etiological treatment with benznidazole. Further prospective studies should be conducted to confirm and validate these findings.
Association between Estrogen Receptors Alpha and Beta and Developmental Defects of Enamel: Cross-Sectional Study
Authors: Vasconcelos Katia Regina Felizardo , Fonseca-Souza Gabriela , Madalena Isabela Ribeiro , Nelson-Filho Paulo , Feltrin-Souza Juliana , Torres Carolina Paes , Matsumoto Mírian Aiko Nakane , Lepri Cesar Penazzo , Kirschneck Christian , Küchler Erika Calvano , Menezes-Oliveira Maria Angelica Hueb de 
Published: November 2023

Background: The genes encoding estrogen receptors alpha and beta (ESR1 and ESR2) are expressed during odontogenesis and may be involved in developmental defects of enamel (DDEs).
Aims: To investigate the association between DDE and genetic polymorphisms ESR1 and ESR2.
Study Design: Cross-sectional.
Place: Department of Orthodontics at School of Dentistry of Ribeirão Preto, University of São Paulo (FORP/USP).
Methodology: Ninety-one (91) patients of both sexes were included in this study (mean age 14.1 ± 5.8 years). DDEs were evaluated by a calibrated examiner using the criteria proposed by Ghanim et al. (2015) (Kappa >0.80). Genomic DNA from saliva was used to evaluate four genetic polymorphisms in ESR1 (rs2234693 and rs9340799) and ESR2 (rs1256049 and rs4986938). Genotyping was performed through Real-Time PCR. The data were analyzed using the PLINK software. Associations were tested by Chi-square or Fisher exact tests. The established alpha was 5%.
Results: A total of 38.5% of the sample presented some DDE (excluding dental fluorosis). DDE was not associated with the polymorphisms rs2234693 and rs9340799 in ESR1 and rs1256049 and rs4986938 in ERS2 (p>0.05).
Conclusion: Genetic polymorphisms in ESR1 and ESR2 were not associated with DDE.