bluuebunny/crossref_metadata_2025_split huggingface dataset:
Agreeableness modulates mental state decoding: Electrophysiological evidence
Authors: Pisanu Elisabetta , Arbula Sandra , Rumiati Raffaella Ida 
Published: January 2024

AbstractAgreeableness is one of the five personality traits which is associated with theory of mind (ToM) abilities. One of the critical processes involved in ToM is the decoding of emotional cues. In the present study, we investigated whether this process is modulated by agreeableness using electroencephalography (EEG) while taking into account task complexity and sex differences that are expected to moderate the relationship between emotional decoding and agreeableness. This approach allowed us to identify at which stage of the neural processing agreeableness kicks in, in order to distinguish the impact on early, perceptual processes from slower, inferential processing. Two tasks were employed and submitted to 62 participants during EEG recording: the reading the mind in the eyes (RME) task, requiring the decoding of complex mental states from eye expressions, and the biological (e)motion task, involving the perception of basic emotional actions through point‐light body stimuli. Event‐related potential (ERP) results showed a significant correlation between agreeableness and the contrast for emotional and non‐emotional trials in a late time window only during the RME task. Specifically, higher levels of agreeableness were associated with a deeper neural processing of emotional versus non‐emotional trials within the whole and male samples. In contrast, the modulation in females was negligible. The source analysis highlighted that this ERP‐agreeableness association engages the ventromedial prefrontal cortex. Our findings expand previous research on personality and social processing and confirm that sex modulates this relationship.
Spatiotemporal signal space separation for regions of interest: Application for extracting neuromagnetic responses evoked by deep brain stimulation
Authors: Oswal Ashwini , Abdi‐Sargezeh Bahman , Sharma Abhinav , Özkurt Tolga Esat , Taulu Samu , Sarangmat Nagaraja , Green Alexander L. , Litvak Vladimir 
Published: January 2024

AbstractMagnetoencephalography (MEG) recordings are often contaminated by interference that can exceed the amplitude of physiological brain activity by several orders of magnitude. Furthermore, the activity of interference sources may spatially extend (known as source leakage) into the activity of brain signals of interest, resulting in source estimation inaccuracies. This problem is particularly apparent when using MEG to interrogate the effects of brain stimulation on large‐scale cortical networks. In this technical report, we develop a novel denoising approach for suppressing the leakage of interference source activity into the activity representing a brain region of interest. This approach leverages spatial and temporal domain projectors for signal arising from prespecified anatomical regions of interest. We apply this denoising approach to reconstruct simulated evoked response topographies to deep brain stimulation (DBS) in a phantom recording. We highlight the advantages of our approach compared to the benchmark—spatiotemporal signal space separation—and show that it can more accurately reveal brain stimulation‐evoked response topographies. Finally, we apply our method to MEG recordings from a single patient with Parkinson's disease, to reveal early cortical‐evoked responses to DBS of the subthalamic nucleus.
Psychosocial factors, health behaviors and risk of cancer incidence: Testing interaction and effect modification in an individual participant data meta‐analysis
Authors: Basten Maartje , Pan Kuan‐Yu , van Tuijl Lonneke A. , de Graeff Alexander , Dekker Joost , Hoogendoorn Adriaan W. , Lamers Femke , Ranchor Adelita V. , Vermeulen Roel , Portengen Lützen , Voogd Adri C. , Abell Jessica , Awadalla Philip , Beekman Aartjan T. F. , Bjerkeset Ottar , Boyd Andy , Cui Yunsong , Frank Philipp , Galenkamp Henrike , Garssen Bert , Hellingman Sean , Huisman Martijn , Huss Anke , Keats Melanie R. , Kok Almar A. L. , Krokstad Steinar , van Leeuwen Flora E. , Luik Annemarie I. , Noisel Nolwenn , Payette Yves , Penninx Brenda W. J. H. , Rissanen Ina , Roest Annelieke M. , Rosmalen Judith G. M. , Ruiter Rikje , Schoevers Robert A. , Soave David , Spaan Mandy , Steptoe Andrew , Stronks Karien , Sund Erik R. , Sweeney Ellen , Twait Emma L. , Teyhan Alison , Verschuren W. M. Monique , van der Willik Kimberly D. , Geerlings Mirjam I. 
Published: January 2024

AbstractDepression, anxiety and other psychosocial factors are hypothesized to be involved in cancer development. We examined whether psychosocial factors interact with or modify the effects of health behaviors, such as smoking and alcohol use, in relation to cancer incidence. Two‐stage individual participant data meta‐analyses were performed based on 22 cohorts of the PSYchosocial factors and CAncer (PSY‐CA) study. We examined nine psychosocial factors (depression diagnosis, depression symptoms, anxiety diagnosis, anxiety symptoms, perceived social support, loss events, general distress, neuroticism, relationship status), seven health behaviors/behavior‐related factors (smoking, alcohol use, physical activity, body mass index, sedentary behavior, sleep quality, sleep duration) and seven cancer outcomes (overall cancer, smoking‐related, alcohol‐related, breast, lung, prostate, colorectal). Effects of the psychosocial factor, health behavior and their product term on cancer incidence were estimated using Cox regression. We pooled cohort‐specific estimates using multivariate random‐effects meta‐analyses. Additive and multiplicative interaction/effect modification was examined. This study involved 437,827 participants, 36,961 incident cancer diagnoses, and 4,749,481 person years of follow‐up. Out of 744 combinations of psychosocial factors, health behaviors, and cancer outcomes, we found no evidence of interaction. Effect modification was found for some combinations, but there were no clear patterns for any particular factors or outcomes involved. In this first large study to systematically examine potential interaction and effect modification, we found no evidence for psychosocial factors to interact with or modify health behaviors in relation to cancer incidence. The behavioral risk profile for cancer incidence is similar in people with and without psychosocial stress.
New definitions, old complications: The association between duration of transition from latent to active labor and adverse obstetrical outcomes
Authors: Zangen Noa R. , Shoham Vardi Ilana , Weintraub Adi Y. , Yaniv Salem Shimrit 
Published: January 2024

AbstractObjectiveTo explore the relationship between the duration of transition from latent to active labor and various obstetric, maternal, fetal, and neonatal outcomes.MethodsA retrospective cohort study was conducted on term, singleton deliveries at Soroka University Medical Center from 2013 to 2018. Data were extracted from electronic medical records. The exposure variable was defined as prolonged transition, which was itself defined as the upper 10th centile of dilation duration from 4 to 6 cm. Clinical and demographic characteristics were compared using χ2 test. Multivariate logistic regression was used to estimate the contribution of a prolonged transition with each adverse outcome adjusting for potential confounders.ResultsIn all, 12 104 deliveries met the inclusion criteria. The mean ± standard deviation of duration of dilation from 4 to 6 cm was 03:07:58 ± 03:03:42 (hours:minutes:seconds). Progress curves varied significantly among patients with different obstetrical and demographic characteristics. Prolonged transition was significantly linked to an increased risk of cesarean delivery (adjusted odds raito 2.607, 95% confidence interval 2.171–3.130, area under the curve 0.689) and higher rates of maternal and neonatal morbidity.ConclusionsPatients experiencing transition phases exceeding the 90th centile faced an elevated risk of cesarean delivery and postpartum complications. Future studies should focus on interventions during the transition phase to improve pregnancy outcomes and enhance patient safety.
Which fetal growth charts should be used in France? Position of the French College of Obstetricians and Gynecologists (CNGOF)
Authors: Verspyck Eric , Senat Marie‐Victoire , Monier Isabelle , Ego Anne , Zeitlin Jennifer , Subtil Damien , Visser Gerard H. A. , Vayssiere Christophe 
Published: January 2024

AbstractObjectiveTo assess which fetal growth charts best describe intrauterine growth in France defined as the ability to classify 10% of fetuses below the 10th percentile (small for gestational age [SGA]) and above the 90th percentile (large for gestational age [LGA]) in the second and third trimesters.MethodsWe analyzed five studies on fetal ultrasound measurements using three French data sources. Two studies used second and third trimester ultrasound data from a nationwide birth cohort in 2011 (the ELFE study, N = 13 197 and N = 7747); one study used third trimester ultrasound data from on a nationwide cross‐sectional study (the 2016 French National Perinatal Survey, N = 9940); and the last two studies were from the “Flash study” 2014 which prospectively collected ultrasound data from routine visits in the second and third trimesters (N = 4858 and N = 3522). For each study, we reported the percentage of measurements below the 10th percentile or above the 90th percentile, using French, Hadlock's, WHO and Intergrowth (IG) charts.ResultsWHO classified 4.7% and 16.3% of fetuses as having an estimated fetal weight (EFW) <10th and >90th percentiles in the second trimester compared to 3.3% and 34.7% with IG. The percentage of fetuses in the third trimester with an EFW <10th and >90th percentiles, ranged from 9.1% to 9.4% and from 8.0% to 11.1%, respectively, for WHO, and from 3.9% to 4.1% and from 17.3% to 21.6%, respectively, for IG. The WHO and IG charts for head circumference were very similar and performed well. Compared to the WHO charts, the French and Hadlock's charts deviated more frequently from the target percentiles values for EFW and biometric measures.ConclusionIt is recommended to use the WHO charts for the assessment of EFW and ultrasound biometric measurements in France (strong recommendation; low quality of evidence).
A patient with oligometastatic hormone‐sensitive prostate cancer who achieved long‐term progression‐free survival following cytoreductive radical prostatectomy and metastasectomy
Authors: Mamiya Daisuke , Kijima Toshiki , Takada‐Owada Atsuko , Kokubun Hidetoshi , Uematsu Toshitaka , Takei Kohei , Kambara Tsunehito , Ishida Kazuyuki , Taneichi Hiroshi , Kamai Takao 
Published: January 2024

IntroductionOligometastatic prostate cancer can be well‐controlled through combined local and metastasis‐directed therapies. However, the effects of cytoreductive radical prostatectomy and metastasectomy remain unclear.Case presentationA 52‐year‐old man presented with prostate cancer and isolated bone metastasis to the thoracic spine. Six months after neoadjuvant hormonal therapy, the patient underwent cytoreductive radical prostatectomy and total en bloc spondylectomy. The postoperative course was uneventful. Hormonal therapy was terminated 5 years after surgery, and no biochemical or radiological progression was observed at 7 years postoperatively.ConclusionAlthough careful patient selection is necessary, cytoreductive radical prostatectomy and metastasectomy are effective treatments for well‐selected patients with oligometastatic prostate cancer.
Increased expression of ATP‐binding cassette transporters in enfortumab vedotin‐resistant urothelial cancer
Authors: Kotono Mariko , Kijima Toshiki , Takada‐Owada Atsuko , Okubo Naoya , Kurashina Ryo , Kokubun Hidetoshi , Uematsu Toshitaka , Takei Kohei , Ishida Kazuyuki , Kamai Takao 
Published: January 2024

IntroductionIn addition to reduced nectin‐4 expression, the upregulation of ATP‐binding cassette transporters has been suggested as a potential mechanism of resistance to enfortumab vedotin.Case presentationA 76‐year‐old man previously treated with platinum‐containing chemotherapy and pembrolizumab for metastatic bladder cancer was administered enfortumab vedotin because of disease progression. Subsequently, metastasectomy was performed for oligometastatic lesions (in the lung and adrenal gland) that exhibited growth during enfortumab vedotin therapy. Immunostaining analysis revealed decreased nectin‐4 expression and elevated MDR1, MRP1, and BCRP expression in the metastatic lesions.ConclusionDecreased nectin‐4 expression and increased ATP‐binding cassette transporter expression are potential factors in the development of enfortumab vedotin resistance in urothelial carcinoma. Immunohistochemical evaluation of these proteins may aid in predicting treatment efficacy.
“Spilling tea”: A critical feminist reclamation of gossip in literature and media
Authors: Batchelor Katherine , Rushek Kelli , Beaumont Julia 
Published: January 2024

AbstractIn this discussion, we argue for those who are literacy educators to reframe gossip as a dialogic, feminist act in their teaching and interpretation of gossip as framed in the literature they teach in secondary English language arts (ELA) classrooms. Reframing gossip as a feminist act invites meaning‐makers to view those conversations and generative dialogues discursively gendered in deficit ways (or gossip) as proactive, productive, and powerful tools of connection between and within societies and communities. We share how we centered and created through a critical feminist lens, an ELA curriculum that supports gossip as a literary tool that drives narratives in plot formation, as well as a means to enhance characters' positions, personalities, allies, and enemies within a story. Most importantly, we use gossip as an analytical tool to reframe and promote gender equity, guiding preservice teachers and adolescents in critical analysis of the innumerable ways systems and institutions of power and privilege—such as race, ethnicity, religion, and sexuality—intersect in the fight for gender equality. First, we will discuss our guiding theoretical framework of critical feminist pedagogy to examine the ELA curriculum. Next, we share how the development of a curricular unit on reframing gossip in literature unfolded organically through a monthly Saturday workshop called “Writing Us In: Developing Critical Literacy Curriculum for ELA Classrooms.” Then, we showcase how one preservice ELA teacher applied the critical feminist lenses examined within the workshop space to develop a linked text set and subsequent ELA curricular unit with the aims of her future students to critically analyze, from a feminist lens, how gossip is portrayed in society and how it is framed in literature. We end with a discussion of how our spotlight student reflects on this project and her key takeaways.
PTCH1 gene variants rs357564, rs2236405, rs2297086 and rs41313327, mRNA and tissue expression in basal cell carcinoma patients from Western Mexico
Authors: Zambrano‐Román Marianela , Padilla‐Gutiérrez Jorge R. , Valle Yeminia , Muñoz‐Valle José F. , Guevara‐Gutiérrez Elizabeth , Martínez‐Fernández Diana Emilia , Valdés‐Alvarado Emmanuel 
Published: January 2024

AbstractBackgroundBasal cell carcinoma (BCC) represents about 80% of all cases of skin cancer. The PTCH1 is a transmembrane protein of the Sonic Hedgehog signaling pathway that regulates cell proliferation. Genetic variants in PTCH1 gene have been previously described in association with BCC development. In addition, PTCH1 mRNA and protein expression analysis are also significant to understand its role in skin cancer physiopathology.MethodsAn analytical cross‐sectional study was performed, and a total of 250 BCC patients and 290 subjects from the control group (CG) were included, all born in western Mexico. The genotypes and relative expression of the mRNA were determined by TaqMan® assay. The protein expression was investigated in 70 BCC paraffin‐embedded samples with PTCH1 antibodies. Semi‐quantitative analysis was performed to determine the expression level in the immunostained cells.ResultsWe did not find evidence of an association between PTCH1 rs357564, rs2297086, rs2236405, and rs41313327 genetic variants and susceptibility to BCC. Likewise, no statistically significant differences were found in the comparison of the mRNA level expression between BCC and CG (p > 0.05). The PTCH1 protein showed a low expression in 6 of the analyzed samples and moderate expression in 1 sample. No association was found between genetic variants, protein expression, and demographic‐clinical characteristics (p > 0.05).ConclusionThe studied PTCH1 variants may not be associated with BCC development in the Western Mexico population. The PTCH1 mRNA levels were lower in patients with BCC compared to the control group, but its protein was underexpressed in the tissue samples.
Granulomatous orchitis: A case report of misdiagnosis and review of the literature
Authors: Song Xinrong , Niu Huimin , Yang Ming , Wang Xiaona 
Published: January 2024

AbstractGranulomatous orchitis is a relatively rare clinical testicular lesion. The imaging manifestations and clinical symptoms are similar to those of testicular tumors. In order to improve the understanding of this disease, this article reports the ultrasonographic manifestations of a case of granulomatous orchitis and reviews the relevant literature with.
Opuntioideae cactus stem Bioimaging analysis: Bridging taxonomy and antimicrobial research
Authors: Almalki Waleed Hassan 
Published: January 2024

AbstractThis study presents a comprehensive scanning electron microscopy (SEM) analysis of Opuntioideae cactus stems indigenous to the arid regions of Saudi Arabia, elucidating their intricate microstructural features. The findings not only advance taxonomic understanding by aiding in species differentiation but also reveal the antimicrobial potential of these cacti, highlighting their significance as valuable natural resources for both ecological and pharmaceutical applications. The present study is aimed to present the stem epidermal anatomical description of Opuntioideae (Cactaceae) belonging to genus Opuntia (five Species), Cylindropuntia (two Species), and Austrocylindropuntia (one Species) as tool for systematic identification. Stem epidermal anatomical features represent here are epidermal cells, stomatal complex, subsidiary cells, and trichomes findings was observed using light microscope and SEM. The stem epidermal sections were made by heating in test tube containing lactic acid and nitric acid protocol. In anatomical findings, irregular, zigzag, wavy, and polygonal epidermal cells with sinuate, sinuous, and straight anticlinal walls were observed. Quantitatively minimum length (28.05 ± 2.05 μm) and width (23.15 ± 3.41 μm) of epidermal cells were noted in Cylindropuntia kleiniae. Paracytic type of stomata present was observed in all species with kidney‐shaped guard cell present in six species, and in Opuntia macrocentra and Austrocylindropuntia subulata, dumbbell‐shaped guard cells were observed. The largest length of stomata (53.25 ± 2.05 μm) and width of stomata (35.10 ± 5.19 μm) were observed in Opuntia monacantha. In present research work, stem anatomical features show many diverse characters are of special attention for plant taxonomist for the correct identification and provide baseline for further study in subfamily Opuntiodeae.Research Highlights
The intricate microstructures of Opuntioideae cactus stems.
Investigating the antimicrobial potential of compounds found within Opuntioideae cactus stems.
Correlations between the unique structural features observed through SEM and the antimicrobial activity of Opuntioideae cactus stem extracts.
Changes in regional daily precipitation intensity and spatial structure from global reanalyses
Authors: Lussana Cristian , Benestad Rasmus , Dobler Andreas 
Published: January 2024

AbstractWe conducted an analysis of hydrological cycle variations across 13 regions of varying sizes distributed across different continents. The analysis is based on five reanalysis datasets of daily precipitation, all produced by the European Centre on Medium‐Range Weather Forecasts (ECMWF): ERA5 high‐resolution, ERA5 ensemble, CERA‐20C, ERA20‐C and ERA20‐CM. We examined several climate indicators, including the daily mean precipitation, the 75th and 99th percentiles, the precipitation area fraction and the area fractions with precipitations exceeding 10 and 20 mm. We evaluated the ability of the reanalyses to capture precipitation at specific spatial scales using scale‐separation diagnostics based on 2D wavelet decomposition. The climatological energy spectra of precipitation derived from the analysis describe the scales that each reanalysis can accurately reproduce, serving as a unique signature for each dataset. We compared the spatial scales that were comparable across the different reanalyses and examined the temporal trends of energy on those scales. The results indicate that the hydrological cycle is undergoing changes in all regions, with some variations observed across different regions. Common features include an increase in intense precipitation events and a decrease in the corresponding spatial extent. The ensemble of ERA5 reanalyses exhibited the smallest effective resolution, as determined by the scale‐separation method, and displayed more pronounced trends compared to other reanalyses. Notably, an acceleration of changes is evident in the last 20 years. However, Central Asia may be an exception, showing relatively less noticeable changes in the hydrological cycle.
Language inclusion in ecological systematic reviews and maps: Barriers and perspectives
Authors: Hannah Kelsey , Haddaway Neal R. , Fuller Richard A. , Amano Tatsuya 
Published: January 2024

AbstractSystematic reviews and maps are considered a reliable form of research evidence, but often neglect non‐English‐language literature, which can be a source of important evidence. To understand the barriers that might limit authors' ability or intent to find and include non‐English‐language literature, we assessed factors that may predict the inclusion of non‐English‐language literature in ecological systematic reviews and maps, as well as the review authors' perspectives. We assessed systematic reviews and maps published in Environmental Evidence (n = 72). We also surveyed authors from each paper (n = 32 responses), gathering information on the barriers to the inclusion of non‐English language literature. 44% of the reviewed papers (32/72) excluded non‐English literature from their searches and inclusions. Commonly cited reasons included constraints related to resources and time. Regression analysis revealed that reviews with larger author teams, authors from diverse countries, especially those with non‐English primary languages, and teams with multilingual capabilities searched in a significantly greater number of non‐English languages. Our survey exposed limited language diversity within the review teams and inadequate funding as the principal barriers to incorporating non‐English language literature. To improve language inclusion and reduce bias in systematic reviews and maps, our study suggests increasing language diversity within review teams. Combining machine translation with language skills can alleviate the financial and resource burdens of translation. Funding applications could also include translation costs. Additionally, establishing language exchange systems would enable access to information in more languages. Further studies investigating language inclusion in other journals would strengthen these conclusions.