bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fractal correlation properties of R‐R interval dynamics in asymptomatic relatives of patients with dilated cardiomyopathy☆
Authors: Mahon Niall G. , Hedman Antti E. , Padula Mina , Gang Yi , Savelieva Irina , Waktare Johan E.P. , Malik Marek M. , Huikuri Heikki V. , McKenna William J. 
Published: October 2002

AbstractBackground and aim:asymptomatic relatives of patients with familial dilated cardiomyopathy who have left ventricular enlargement [LVE] are at risk for progression to dilated cardiomyopathy. A novel index of the fractal correlation properties of heart rate variability (HRV), the short‐term scaling component (∝1) in detrended fluctuation analysis, is a promising prognostic tool in left ventricular dysfunction. The aim of this study was to compare values of ∝1 and conventional HRV indices in LVE relatives with dilated cardiomyopathy patients and normal controls.Methods:time‐domain and spectral HRV measures, and the short‐term scaling component (∝1) were assessed from 24‐h Holter recordings from 22 LVE relatives (left ventricular end‐diastolic dimension >112% predicted, normal fractional shortening), 24 dilated cardiomyopathy patients and 14 controls.Results:the time domain index SDNN was lower in dilated cardiomyopathy patients [101.8(±44.0)] than in LVE relatives [161.7(±53.9)] or controls [152.9(±51.4)], P ‐ 0.01. Similarly, triangular index and spectral measures were reduced in dilated cardiomyopathy patients but not in LVE relatives or controls. In contrast, the short term scaling component (∝1) in detrended fluctuation analysis was reduced in both dilated cardiomyopathy patients [1.06(±0.33)] and in LVE relatives [1.15 (±0.20)], compared with controls [1.32(±0.16)], P ‐ 0.01. Among DCM patients the short‐term scaling component (∝1) was significantly associated with echocardiographic deterioration during follow‐up (3.7±2.1 year) (P ‐ 0.004).Conclusion:the short‐term scaling component (∝1) is reduced in asymptomatic relatives of dilated cardiomyopathy patients who have LVE.
Synthesis and Characterization of a Tetrahedral and Octahedral Cobalt(II) Alternate Chain Complex
Authors: Kumagai Hitoshi , Ohba Masaaki , Inoue Katsuya , Okawa Hisashi 
Published: October 2002

Abstract
Reaction between Co(II) ion and 4-phenoxybenzoate (L) under hydrothermal conditions gives a one-dimensional coordination polymer, [Co2L4]. [Co2L4] consists of dinuclear motifs of pseudo octahedral {CoO6} and tetrahedral {CoO4} linked through μ-carboxylate ligands. The temperature dependence of magnetic susceptibility revealed the presence of ferromagnetic interaction between the adjacent tetrahedral Co(II) and octahedral Co(II) ions.
Supercritical Carbon Dioxide-Induced Epitaxy on the Surface of Nylon1212 Substrate
Authors: Chang Yuning , Xu Qun 
Published: October 2002

Abstract
In this study we focus on the influence of the absorbed supercritical (SC) CO2 on the surface aggregation structure of the substrate polymer, nylon1212. Both virgin and treated nylon1212 were measured or observed with wide-angle X-ray diffraction (WAXD), micropolariscope and SEM. A novel phenomenon, SC CO2-induced epitaxy (crystalline overgrowth) was discovered and the mechanism is deduced.
Mesoporous Zirconium Phosphate-phenylphosphonate and Its Functionalization
Authors: Ren N , Tang Y , Wang Y J , Hu S H , Dong A G , Hua W M , Yue Y H , Shen J Y 
Published: October 2002

Abstract
Mesoporous zirconium phosphate-phenylphosphonate has been prepared in the presence of cetyltrimethylammonium bromide as the template. The phenyl groups on the pore wall could be easily sulphonated or brominated to endow the sample with more functionalities.
Solvothermal Preparation of Sb2Se3 Nanowires
Authors: Wang Debao , Yu Dabin , Shao Mingwang , Yu Weichao , Qian Yitai 
Published: October 2002

Abstract
Crystalline Sb2Se3 nanowires with a typical width of 30 nm and length up to 8 μm were synthesized through the reaction between SbCl3 and elemental selenium with sodium sulfite as reducing reagent in diethylene glycol solution. The composition of the products was identified using EDX and XPS. The possible reaction mechanism was also discussed.
Preparation of Ordered Supermicroporous Niobium Oxide
Authors: Lee Byongjin , Lu Daling , Kondo Junko N , Domen Kazunari 
Published: October 2002

Abstract
Ordered supermicroporous (1.0–2.0 nm) niobium oxide was prepared by sol-gel method using neutral templating route, where the template was removed by water washing after 2-step aging.
Continuous Preparation of CdSe Nanocrystals by a Microreactor
Authors: Nakamura Hiroyuki , Yamaguchi Yoshiko , Miyazaki Masaya , Uehara Masato , Maeda Hideaki , Mulvaney Paul 
Published: October 2002

Abstract
In order to provide a continuous preparation method of CdSe nanocrystals, a microreactor was utilized. Particle size of a CdSe was controlled easily by a second order controlling of reaction time. The fluorescence color was also possible to be controlled by the reaction time.
Magnetic Alignment of Polypyrrole Layered Structures by Repeated Redox Cycles
Authors: Morioka Hiroyuki , Kimura Tsunehisa , Aogaki Ryoichi 
Published: October 2002

Abstract
A perchlorate-doped polypyrrole was processed by repeated redox cycles in a 0.1 M NaClO4 aqueous solution under a magnetic field applied parallel to the faradic current. The film that was initially isotropic underwent magnetic alignment. X-ray measurement revealed that the polypyrrole layered structures were aligned perpendicular to the electrode surface.
Photocatalytic Activity of Phthalocyaninatozinc(II) Bearing Dendritic Subsituents at α Positions in Aerated Dimethyl Sulfoxide
Authors: Kasuga Kuninobu , Akita Tadaaki , Matsuura Noriyuki , Handa Makoto , Sugimori Tamotsu 
Published: October 2002

Abstract
The title complexes acted as sensitizers for photooxidation in irradiation with visible light in aerated dimethyl sulfoxide. The reaction proceeded via a singlet-oxygen pathway. The oxidation rate decreased with increasing the number of dendrimer generation.
Phase Transformation from Lamellar to Hexagonal in Mesostructured Silica Thin Films by a Water Vapor Hydrothermal Method
Authors: Wu Chia-Wen , Pang Jie-Bin , Kuwabara Makoto 
Published: October 2002

Abstract
The phase transformation from lamellar to 2-dimensional (2D) hexagonal structure has been observed in mesostructured silica thin films, synthesized using a self-assembly triblock copolymer (EO20PO70EO20, P123) as a template, during heat treatment under water vapor hydrothermal conditions.
Formation of Amino Acids from Possible Interstellar Media by γ-rays and UV Irradiation
Authors: Takano Yoshinori , Masuda Hitomi , Kaneko Takeo , Kobayashi Kensei 
Published: October 2002

Abstract
Formation of amino acids from mixtures of methanol, ammonia and water in various phases by γ-rays and UV irradiation were quantitatively verified. A wide variety of amino acids were detected in every hydrosate of the product. Each G-value (the number of formed molecules per deposit energy of 100 eV) was around 10−2 order, which was independent from the phase of the starting materials and kind of the energy.
Self‐Assembled Monolayer Assisted Biphasic Heterojunction Organic Photodiode for Panel‐Level Manufacturing of Active‐Matrix Optical Imager
Authors: Shan Tong , Li Jun , Bai Qing , Zhang Ming , Shi Rongrong , Zhong Hongliang , He Bin , Li Shunpu , Guo Xiaojun 
Published: January 2025

AbstractOrganic photodiodes (OPDs) have shown great promises for large‐area optical imagers attributed to ease of processing and tunable performance in a wide wavelength range. A biphasic heterojunction (BPHJ) OPD design, having a bulky heterojunction structure on top of a monophasic donor layer, is proposed in this work. The BPHJ structure is spontaneously formed on a self‐assembled monolayer (SAM) treated indium tin oxide surface by depositing the donor and acceptor layers sequentially. The fabricated OPDs present significantly reduced dark current and meanwhile improved specific detectivity with a larger linear dynamic range and faster response compared to the conventional devices. This strategy is proved to be universal to various donor/acceptor combinations, covering a wide range of wavelength from visible to near‐infrared. Such a BPHJ structure is well compatible for the back‐end‐of‐line integration processes on top of the TFT backplane from the semiconductor display fab. An active‐matrix imager with an ultralow detection limit can reproduce ideal image quality under an ultra‐low light intensity of nW cm−2 level.
Optical Hydrogen Sensing Materials for Applications at Sub‐Zero Temperatures
Authors: Yuan Ziqing , Schreuders Herman , Dankelman Robert , Dam Bernard , Bannenberg Lars J. 
Published: January 2025

AbstractOptical hydrogen sensors have the power to reliably detect hydrogen in an inherently safe way, which is crucial to ensure safe operation and prevent emissions of hydrogen as an indirect greenhouse gas. These sensors rely on metal hydride material that can reversibly absorb hydrogen when it is present in the environment, and as a result, change their optical properties. To apply this technology along hydrogen infrastructure, in hydrogen‐powered planes and other vehicles, it is crucial that these sensors can operate down to −60 °C, a challenge so far unaddressed. Here, it is showed that metal hydride hydrogen sensing materials can be used to detect hydrogen optically down to −60 °C in just a couple of seconds and across a hydrogen concentration range of 0.02–100% with a 1% change in transmission per order of magnitude change in hydrogen concentration. The in‐situ X‐ray diffraction and optical transmission measurements show that Ta, Ta88Pd12, Ta88Ru12, and Pd60Au40 can gradually, reversibly and hysteresis‐free absorb hydrogen while providing sufficient optical contrast. Specifically, Ta88Ru12 possesses the largest optical contrast and the swiftest response down to 6 s at −60 °C. These results confirm the operational viability and foretell new applications of metal hydride hydrogen sensing in cold conditions.
Seawater Interfacial Evaporation in Composite Gel Enables Photovoltaic Cooling, Simultaneous Seawater Desalination, and Enhanced Uranium Extraction
Authors: Su Yuqing , Gu Ruonan , Li Yangxi , Wu Wei , Yu Zhen , Cheng Shaoan 
Published: January 2025

AbstractOverheating of photovoltaic (PV) panels poses a huge challenge to their practical operation. Herein, a novel design is proposed that uses seawater interfacial evaporation to integrate PV cooling, seawater desalination, and uranium extraction. The sodium alginate (SA) gel with uranium adsorbent filled is utilized to verify the efficacy of this design. As light intensity increases from 0.5 to 1.5 suns, the evaporation rate of doped SA gel rises from 0.98 to 2.62 kg m−2 h−1, and the output gain of the PV panel increases from 4.9 to 13.1% owing to the cooling effect of this gel. Additionally, a high uranium adsorption ratio exceeding 90% in 50 mg L−1 uranium solution or seawater is obtained under 1 sun (in‐lab). The outdoor experiments imply that the composite gel can lower the surface temperature of the PV panel by up to 12 °C, with a maximum output gain of 8%. Meanwhile, a high uranium capacity of 6 mg g−1 over 10 days is also obtained. In summary, our work shows a meaningful solution for multiple uses of seawater resources and energy through offshore PV platforms.
Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges
Authors: Wilson John Nikita , Dang Caitlyn , Reddy Nidhi , Chao Calvin , Ho Karen J. , Jiang Bin 
Published: January 2025

AbstractNeointimal hyperplasia, a pathological response to arterial interventions or injury, often leads to restenosis and recurrent narrowing or occlusion, particularly in the peripheral vasculature. Its prevalence and negative impact on the long‐term success of vascular interventions have driven extensive research aimed at better understanding the condition and developing effective therapies. This review provides a comprehensive overview of emerging bioengineering strategies for treating neointimal hyperplasia in peripheral vessels. These approaches include novel therapeutics and cell‐based technologies designed to promote re‐endothelialization, modulate vascular smooth muscle cell (VSMC) phenotype, reduce inflammation, scavenge reactive oxygen species (ROS), and enhance biomechanical compatibility between grafts and native vessels. Furthermore, advanced therapeutic delivery modalities are highlighted for their potential to achieve targeted, localized treatment at injury sites. This review also explores underrepresented therapeutic targets beyond traditional approaches, offering new opportunities for intervention. The multifaceted examination underscores the challenge of neointimal hyperplasia and presents a promising roadmap toward more effective treatments, ultimately aiming to improve patient outcomes after vascular interventions.
Tissue Mimetic Membranes for Healing Augmentation of Tendon–Bone Interface in Rotator Cuff Repair
Authors: Zhu Yuwei , Dai Bingyang , Zhang Shian , Liu Jun , Xu Shunxiang , Liu Weiyang , Chen Xin , Zhang Haozhi , Li Quan , Pang Florence Ou‐Suet , Li Weiguo , Wen Chunyi , Qin Ling , Xu Jiankun , Ngai To 
Published: January 2025

AbstractThe globally prevalent rotator cuff tear has a high re‐rupture rate, attributing to the failure to reproduce the interfacial fibrocartilaginous enthesis. Herein, a hierarchically organized membrane is developed that mimics the heterogeneous anatomy and properties of the natural enthesis and finely facilitates the reconstruction of tendon–bone interface. A biphasic membrane consisting of a microporous layer and a mineralized fibrous layer is constructed through the non‐solvent induced phase separation (NIPS) strategy followed by a co‐axial electrospinning procedure. Cationic kartogenin (KGN)‐conjugated nanogel (nGel‐KGN) and osteo‐promotive struvite are incorporated within the membranes in a region‐specific manner. During in vivo repair, the nGel‐KGN‐functionalized microporous layer is adjacent to the tendon which intends to suppress scar tissue formation at the lesion and simultaneously heightens chondrogenesis. Meanwhile, the struvite‐containing fibrous layer covers the tubercula minus to enhance stem cell aggregation and bony ingrowth. Such tissue‐specific features and spatiotemporal release behaviors contribute to effective guidance of specific defect‐healing events at the transitional region, further leading to the remarkably promoted regenerative outcome in terms of the fibrocartilaginous tissue formation, collagen fiber alignment, and optimized functional motion of rotator cuff. These findings render a novel biomimetic membrane as a promising material for clinical rotator cuff repair.
A Bifunctional Lysosome‐Targeting Chimera Nanoplatform for Tumor‐Selective Protein Degradation and Enhanced Cancer Immunotherapy
Authors: Xing Yumeng , Li Jingjing , Wang Leyuan , Zhu Zhihui , Yan Jian , Liu Yang , Liu Qi 
Published: January 2025

AbstractLysosome‐targeting chimeras (LYTACs) have recently emerged as a promising therapeutic strategy for degrading extracellular and membrane‐associated pathogenic proteins by hijacking lysosome‐targeting receptors. However, the antitumor performance of LYTAC is limited by its insufficient tumor accumulation and nonspecific activation. Additionally, the synergistic effects of LYTACs and other therapeutic modalities are crucial. To address these issues, a bifunctional LYTAC nanoplatform (NLTC) is developed for tumor‐selective protein degradation and enhanced cancer immunotherapy. By rationally controlling the surface composition, the NLTC can effectively transport extracellular or membrane proteins into lysosomes for degradation via cation‐independent mannose 6‐phosphate receptors. With removable surface modification, an NLTC is obtained that efficiently accumulated in tumor tissues and avoided on‐target off‐tumor toxicity. Moreover, the synthesis method of NLTC is generally applicable to various enzymes. Thus, catalase (CAT) is encapsulated with NLTC to synergistically degrade cancer cell surface programmed death ligand‐1 (PD‐L1), relieve the immunosuppressive tumor microenvironment for effective cancer immunotherapy, and significantly inhibit tumor growth, recurrence, and metastasis in B16F10‐bearing mice. This work presents a bifunctional LYTAC nanoplatform that can not only perform tissue‐selective protein degradation but also integrate other therapeutic modalities, providing insights into the design of advanced LYTAC technologies for clinical applications.
Ultrafast Li‐Rich Transport in Composite Solid‐State Electrolytes
Authors: Liao Yu‐Long , Wang Xi‐Long , Yuan Hong , Li Yong‐Jian , Xu Chun‐Ming , Li Shuai , Hu Jiang‐Kui , Yang Shi‐Jie , Deng Fang , Liu Jia , Huang Jia‐Qi 
Published: January 2025

AbstractSolid‐state lithium (Li) metal batteries (SSLMBs) have garnered considerable attention due to their potential for high energy density and intrinsic safety. However, their widespread development has been hindered by the low ionic conductivity of solid‐state electrolytes. In this contribution, a novel Li‐rich transport mechanism is proposed to achieve ultrafast Li‐ion conduction in composite solid‐state electrolytes. By incorporating cation‐deficient dielectric nanofillers into polymer matrices, it is found that negatively charged cation defects effectively intensify the adsorption of Li ions, resulting in a high Li‐ion concentration enrichment on the surface of fillers. More importantly, these formed Li‐rich layers are interconnected to establish continuous ultrafast Li‐ion transport networks. The composite electrolyte exhibited a remarkably low ion transport activation energy (0.17 eV) and achieved an unprecedented ionic conductivity of approaching 1 × 10⁻3 S cm⁻1 at room temperature. The Li||LiNi0.8Co0.1Mo0.1O2 full cells demonstrated an extended cycling life of over 200 cycles with a capacity retention of 70.7%. This work provides a fresh insight into improving Li‐ion transport by constructing interconnected Li‐rich transport networks, paving the way for the development of high‐performance SSLMBs.
DNA Polymerase IV dinB Favors the Adaptive Fitness of mcr‐carrying Bacteria Through a Negative Feedback Regulatory Mechanism
Authors: Zhang Haijie , Xiao Xia , Wang Chenlong , Zhao Yurong , Chen Bo , Ji Xinyuan , Gu Lina , Wang Jie , Wang Zhiqiang , Liu Yuan 
Published: January 2025

AbstractThe plasmid‐borne resistance gene mcr drastically undermines the effectiveness of colistin, posing a substantial threat to public health. Although several key plasmid elements that balance mcr‐1 persistence and bacterial growth are identified, the regulatory interactions between mcr‐1 and host bacteria remain poorly understood. Using a genome‐wide CRISPRi crRNA library, it is identified that DNA polymerase IV, dinB, is essential for controlling the fitness cost associated with mcr‐1 in Escherichia coli. The absence of dinB operon enhances mcr‐1‐mediated colistin resistance but simultaneously compromises bacterial growth and competitiveness. Meanwhile, dinB deficiency mitigates inflammatory response in RAW267.4 cells and enhances bacterial colonization in murine tissues. Further investigation reveals that mcr‐1 actively upregulates dinB expression, with the increased reactive oxygen species induced by mcr‐1 being crucial for this activation. These findings suggest that dinB modulates mcr expression and bacterial fitness via a negative feedback regulatory mechanism. Leveraging this regulatory relationship, a Toxin‐Intein is engineered under the control of dinB promoter to selectively target and kill mcr‐positive E. coli both in vitro and in vivo. Overall, the work uncovers a novel adaptive mechanism underlying mcr persistence and provides a precise antimicrobial strategy to combat antibiotic‐resistant pathogens.
Highly Efficient and Durable Ammonia Electrolysis Cell Using Zirfon Separator
Authors: Shin Haeyong , Jung Sang‐Mun , Lim Young Jin , Yim O‐Jung , Lee Byung‐Jo , Kim Kyu‐Su , Baek In‐Ho , Baek Jinwoo , Lee Jinhyeon , Kim Yong‐Tae 
Published: January 2025

AbstractMost studies on ammonia electrolysis have focused on anion exchange membranes (AEMs), which face limitations in operating conditions, such as pH and ammonia concentration. This study introduces a novel concept of an ammonia electrolysis cell (AEC) utilizing a Zirfon separator capable of operating under high pH and ammonia concentrations. The Zirfon‐based AECs achieve a peak current density of 915 mA cm−2, representing the highest reported value in AEC literature. Additionally, the Zirfon separator exhibits less conductivity degradation than AEMs during cycling tests (Zirfon 14.1%, AEMs 30.2%), demonstrating superior durability of the Zirfon‐based AEC.
In Operando Visualization of Charge Transfer Dynamics in Transition Metal Compounds on Water Splitting Photoanodes
Authors: Ning Xingming , Zhang Shengya , Yin Dan , Du Peiyao , Lu Xiaoquan 
Published: January 2025

AbstractSolar‐driven photoelectrochemical (PEC) water splitting provides a highly promising solution for converting solar energy to chemical fuels. The semiconductor (SC) based photoanode often exhibits enhanced PEC performance when coated with a transition metal compound (TMC) overlayer that is merely regarded as a cocatalyst for the oxygen evolution reaction (OER). However, the origin of this improvement and the distinct roles of TMCs remain controversial topics. This is mainly due to a lack of advanced characterization techniques that can in operando capture the photogenerated charge transfer dynamics in such multicomponent SC/TMC systems. Herein, how the aforementioned issue can be addressed using in situ visualization characterization is presented, i.e., scanning photoelectrochemical microscopy (SPECM), and ultraviolet/visible‐spectroelectrochemistry (UV/vis‐SEC). By employing these techniques to BiVO4 (BV) combined with various TMCs (e.g., CoPi, Ni(OH)x, and Fe(OH)x), it is found that in addition to the superior OER activity of TMC overlayers, special attention should be paid to the fast hole transfer dynamics, especially for achieving the desirable PEC performance. As expected, further loading iron‐nickel oxyhydroxide (FeNi‐H) layer onto the BV/Fe(OH)x photoanodes (relatively fast hole transfer ability), the BV/Fe(OH)x/FeNi‐H achieves the highest photocurrent density among all counterparts.
Reconfiguring Terminal Species of Bituminous Coal to Steer Hard Carbon toward High‐Capacity and Fast Sodium Storage
Authors: Huang Yaxin , Hou Zhidong , Wang Jianfang , Li Yongli , Ma Ting , Nan Ding , Wei Chunguang , Wang Jian‐Gan 
Published: January 2025

AbstractHard carbons derived from coal precursors have shown bright industrial prospect as the low cost anode materials of sodium‐ion batteries. However, it is of extreme necessity yet challenge to regulate carbon microstructure toward superior sodium energy storage. In this study, we propose a powerful chemical reconfiguration tactic to steer hard carbons toward high‐capacity and fast sodium storage. The functional species on the edge/plane terminals of bituminous coal are finely reconfigured by nitri‐oxidation treatment for effectively inhibiting the reordering of carbon layers under high temperature, thereby creating rich ultramicropores/closed pores and expanded interlayer spacing. These structural merits enable the hard carbon to garner an enhanced capacity of 356 mAh g−1 along with a high initial Coulombic efficiency of 88.1 % and long lifespan. More impressively, the sodium storage kinetics is substantially sped up with a large capacity of 215 mAh g−1 retained at a high‐rate of 2 A g−1. This work will afford a fresh methodology for precursor modulation to accelerate the real‐world practice of hard carbons toward advanced sodium‐ion batteries.