bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of Critical Stack Pressure and Temperature in Li‐Garnet Batteries
Authors: Klimpel Matthias , Zhang Huanyu , Paggiaro Giulia , Dubey Romain , Okur Faruk , Jeurgens Lars P.H. , Kravchyk Kostiantyn V. , Kovalenko Maksym V. 
Published: January 2024

AbstractStack pressure and temperature serve as effective means to induce deformation of the lithium metal anode toward the Li/solid‐state‐electrolyte interface, thereby mitigating the well‐known issue of void formation during high‐current‐density stripping. In this study, a compelling methodology is systematically assessed for determining the critical stack pressure and temperature of Li metal anode in conjunction with Li7La3Zr2O12 (LLZO) solid‐state electrolyte, which is the minimum set of values required to maintain conformal contact between Li and LLZO at a given current density. The methodology is based on the analysis of the second derivatives of the voltage profiles of identical Li/LLZO/Li symmetric cells measured during one half‐cycle (3 mAh cm‐2) at the same current density but different stack pressures. The effectiveness of the presented approach in assessing conditions for mitigating void formation during Li stripping is evaluated through cycle stability tests performed on Li/LLZO/Li symmetric cells.
Toward Printing the Brain: A Microstructural Ground Truth Phantom for MRI
Authors: Woletz Michael , Chalupa‐Gantner Franziska , Hager Benedikt , Ricke Alexander , Mohammadi Siawoosh , Binder Stefan , Baudis Stefan , Ovsianikov Aleksandr , Windischberger Christian , Nagy Zoltan 
Published: January 2024

AbstractMagnetic resonance imaging (MRI) has become the prime imaging technique for in vivo examination of the brain. In addition to anatomical and functional MRI, diffusion MRI (dMRI) is widely used in both clinics and research to assess tissue structure and fiber directions, particularly in the nervous system. While diffusion tensor imaging is the most widespread approach for assessing orientation measures, other, more sophisticated models have also been proposed. Validation of dMRI is, however, a challenging endeavor that requires specialized test samples. Here it is shown that two‐photon polymerization (2PP) 3D printing allows for manufacturing such test objects, a.k.a. phantoms. After upscaling the 2PP fabrication process, 3D structures at high spatial resolution and sufficient size to image in a human 7T MRI scanner are created. These phantoms reliably mimic human white matter and thus enable the systematic validation and verification of dMRI data and their analyses. The 3D‐printed structures include up to 51 000 microchannels that mimic the diffusion behavior of larger axons, with a cross‐section of 12 × 12 µm2 each, in parallel and crossing arrangements. The acquired dMRI data demonstrates and verifies the utility of these novel brain phantoms.
In Situ Transmission Electron Microscopy Observation of Electrochemical Process Between Li–C Nanocomposites and Multilayer Graphene
Authors: Lin Wei Ming , Suresh Giri , Gupta Vikaskumar Pradeepkumar , Tomida Shota , Oyama Kento , Yaakob Yazid , Asaka Toru , Sonoyama Noriyuki , Yusop Mohd Zamri Mohd , Tanemura Masaki 
Published: January 2024

AbstractPortable power supplies, particularly lithium‐ion batteries (LIBs), will play a key role in achieving sustainable development goals, and electrode active materials for the next generation of LIBs with higher energy density and longer life time is highly demanded. For this, in situ visualization of Li behavior during the charge/discharge process is essential, and transmission electron microscopy (TEM) will be promising for this purpose. Here, a quite simple experimental setup consisting of a newly developed Li–C nanocomposite film sputter‐deposited onto Au nanoprotrusions at room temperature and graphene synthesized on a W probe at 500 °C for the in situ TEM observation of the battery reaction is proposed. The preservation of the metallic Li in the Li–C film that is transferred to TEM without using any transfer vessels under atmospheric conditions is confirmed by high resolution TEM before the in situ electrochemical process in TEM. After the one cycle of the in situ electrochemical process, the intercalation of Li ions into graphene (lithiation) is clearly observed. Thus, it is concluded that the metallic Li stored in the Li–C film works well as the anode active material in the electrochemical process for solid state LIBs, implying the developed in situ experimental system is promising.
Piezoelectric Nanocomposite‐Based Multifunctional Wearable Bioelectronics for Mental Stress Analysis Utilizing Physiological Signals
Authors: Kim Mookyum , Joe Daniel J. , Doh Il , Cho Young‐Ho 
Published: January 2024

AbstractThis study multifunctional wearable bioelectronics (MWBs) integrated with a piezoelectric sensor and a micropatterned temperature sensor for accurate detection of human physiological signals. Piezoelectric nanocomposite uniformity, stretchability, and adhesion is improved through the functionalization of nanoparticles with glycidyl silane and nonionic surfactants dispersion in the organic polymer matrix. Additionally, crack‐free nanometal layers are deposited on the nanocomposite interface with high adhesion by thiol silane functionalization and oxygen plasma treatment. The MWBs exhibit a temperature sensitivity of 7.1 Ω °C−1 (R2 of 0.999) between 30 °C to 40 °C, a pressure sensitivity of 72 mV kPa−1 (R2 of 0.998) within 0.5 kPa to 10 kPa, and a stable mechanical durability. MWBs have demonstrated to detect subtle pulse waveforms at an arm‐mimicking phantom and human skin, respectively. Furthermore, MWBs are applied to analyze physiological signal characteristics caused by human stress, demonstrating its potential for use in healthcare electronics in various medical applications.
An Enzyme‐Encapsulated Metal‐Organic Frameworks Nanomesh Biosensor for Salivary Glucose Detection
Authors: Wang Muxue , Wang Han , Cheng Jing 
Published: January 2024

AbstractDiabetes mellitus has become a serious public health problem worldwide. Current home‐based glucose testing, including fingerstick blood testing and continuous glucose monitoring, suffers from low compliance and potential infection. Non‐invasive glucose detection, with the advantages of pain‐free, easy‐to‐operate, and low‐cost, is expected to significantly improve the experience of glucose testing at home for diabetic patients. Here, an enzymatic biosensing platform with high sensitivity and high stability is developed based on a conductive nanomesh composed of interconnected metal‐organic frameworks (MOF). The as‐prepared enzyme‐encapsulated MOF nanomesh exhibits uniform morphology, regular structure, superior catalytic performance, and outstanding electrical conductivity. The glucose sensor modified by enzyme‐encapsulated MOF nanomesh demonstrates a considerably high sensitivity of 86.86 µA mm−1 cm−2 with a limit of detection of 16.57 µm, and remains stable for 16 days of usage. Detection of real saliva samples matches well with the commercial salivary glucose assay kit with an accuracy >93%, and a high correlation with blood glucose with Pearson's r > 0.7. Therefore, the presented enzyme‐encapsulated MOF nanomesh biosensor holds great potential in salivary glucose testing and provides a novel strategy for noan‐invasive glucose detection.
AAV‐Mediated Gene Therapy Restores Hearing in Patients with DFNB9 Deafness
Authors: Qi Jieyu , Tan Fangzhi , Zhang Liyan , Lu Ling , Zhang Shanzhong , Zhai Yabo , Lu Yicheng , Qian Xiaoyun , Dong WenXiu , Zhou Yinyi , Zhang Ziyu , Yang Xuehan , Jiang Lulu , Yu Chaorong , Liu Jiancheng , Chen Tian , Wu Lianqiu , Tan Chang , Sun Sijie , Song Huaien , Shu Yilai , Xu Lei , Gao Xia , Li Huawei , Chai Renjie 
Published: January 2024

AbstractMutations in OTOFERLIN (OTOF) lead to the autosomal recessive deafness 9 (DFNB9). The efficacy of adeno‐associated virus (AAV)‐mediated OTOF gene replacement therapy is extensively validated in Otof‐deficient mice. However, the clinical safety and efficacy of AAV‐OTOF is not reported. Here, AAV‐OTOF is generated using good manufacturing practice and validated its efficacy and safety in mouse and non‐human primates in order to determine the optimal injection dose, volume, and administration route for clinical trials. Subsequently, AAV‐OTOF is delivered into one cochlea of a 5‐year‐old deaf patient and into the bilateral cochleae of an 8‐year‐old deaf patient with OTOF mutations. Obvious hearing improvement is detected by the auditory brainstem response (ABR) and the pure‐tone audiometry (PTA) in these two patients. Hearing in the injected ear of the 5‐year‐old patient can be restored to the normal range at 1 month after AAV‐OTOF injection, while the 8‐year‐old patient can hear the conversational sounds. Most importantly, the 5‐year‐old patient can hear and recognize speech only through the AAV‐OTOF‐injected ear. This study is the first to demonstrate the safety and efficacy of AAV‐OTOF in patients, expands and optimizes current OTOF‐related gene therapy and provides valuable information for further application of gene therapies for deafness.
In Situ Probing the Crystallization Kinetics in Gas‐Quenching‐Assisted Coating of Perovskite Films
Authors: Qiu Shudi , Majewski Martin , Dong Lirong , Jang Dongju , Corre Vincent M. Le , Cerrillo José Garcia , Ronsin Olivier J. J. , Yang Fu , Guo Fei , Zhang Kaicheng , Lüer Larry , Harting Jens , Du Tian , Brabec Christoph J. , Egelhaaf Hans‐Joachim 
Published: January 2024

AbstractThe pursuit of commercializing perovskite photovoltaics is driving the development of various scalable perovskite crystallization techniques. Among them, gas quenching is a promising crystallization approach for high‐throughput deposition of perovskite films. However, the perovskite films prepared by gas‐quenching assisted blade coating are susceptible to the formation of pinholes and frequently show inferior crystallinity if the interplay between film coating, film drying, and crystallization kinetics is not fully optimized. That arguably requires a thorough understanding of how single processing steps influence the crystallization kinetics of printed perovskite films. Here, in situ optical spectroscopies are integrated into a doctor‐blading setup that allows to real‐time monitor film formation during the gas‐quenching process. It is found that the essential role of gas quenching treatment is in achieving a smooth and compact perovskite film by controlling the nucleation rate. Moreover, with the assistance of phase‐field simulations, the role of excessive methylammonium iodide is revealed to increase grain size by accelerating the crystal growth rate. These results show a tailored control of crystal growth rate is critical to achieving optimal film quality, leading to fully printed solar cells with a champion power conversion efficiency of 19.50% and mini solar modules with 15.28% efficiency are achieved.
Soil texture and organic matter prediction using Mehlich‐3 extractable nutrients
Authors: Drescher Gerson L. , Slaton Nathan A. , Roberts Trenton L. , Smartt Alden D. 
Published: January 2024

AbstractSoil organic matter (SOM) and texture are key properties influencing soil nutrient and water dynamics but are time‐consuming procedures for analytical laboratories. Our objective was to evaluate SOM and soil texture predictions using Mehlich‐3 nutrients and pH in Arkansas soils. Particle size was determined by the hydrometer method (2‐ and 8‐h readings) and SOM by loss on ignition. Two datasets were used to calibrate clay and sand (n = 409) and SOM (n = 1019) prediction models using simple and multiple regression. Estimated cation exchange capacity was highly correlated with clay, resulting in significant prediction models alone or combined with phosphorus (P); pH and copper (Cu); or pH, sodium (Na), and Cu (R2 = 0.84, 0.88, 0.89, and 0.90; p < 0.0001, respectively). Soil nutrients were weakly correlated with sand, resulting in a prediction model with moderate accuracy when using Mehlich‐3 P, calcium (Ca), Na, iron (Fe), and manganese (Mn) (R2 = 0.49; p < 0.0001). Clay and sand prediction models presented comparable accuracy when validated on a new dataset (n = 103). Predicted sand and clay showed good accuracy in grouping soils into medium (65%) and fine (96%) textural categories but had limited ability to define the coarse‐textural group (9%). SOM had moderate goodness‐of‐fit statistics for calibration and validation datasets using pH, P, Ca, Na, Mn, and zinc (R2 = 0.65 and 0.70, respectively; p < 0.0001). Mehlich‐3 nutrients can be used to estimate soil texture and assist with crop management decisions, but further research is needed to improve SOM prediction.
The first Turkish family with a novel biallelic missense variant of the ALKBH8 gene: A study on the clinical and variant spectrum of ALKBH8‐related intellectual developmental disorders
Authors: Yılmaz Mustafa , Kamaşak Tülay , Teralı Kerem , Çebi Alper Han , Türkyılmaz Ayberk 
Published: January 2024

AbstractABH8, the protein encoded by the ALKBH8 gene, modifies tRNAs by methylating their anticodon wobble uridine residues. The variations in the ALKBH8 gene are associated with the “intellectual developmental disorder, autosomal recessive type 71” (MIM: 618504) phenotype in the OMIM database. This phenotype is characterized by global developmental delay, facial dysmorphic features, and psychiatric problems. To date, 12 patients from five distinct families carrying variants of the ALKBH8 gene have been reported in the literature. In the present study, we report the first Turkish family harboring a novel homozygous missense variant, NM_138775.3:c.1874G > C (p.Arg625Pro), in the last exon of the ALKBH8 gene. Two affected siblings in this family showed signs of global developmental delay and intellectual disability. Based on the dysmorphological assessment of the cases, fifth finger clinodactyly and fetal fingertip pads were prominent, in addition to the dysmorphic findings similar to those reported in previous studies. Minor dysmorphic limb anomalies in relation to this phenotype have not yet been previously reported in the literature. Our computational studies revealed the potential deleterious effects of the Arg‐to‐Pro substitution on the structure and stability of the ABH8 methyltransferase domain. In the present report, the first Turkish family with an ultrarare disease associated with the ALKBH8 gene was reported, and a novel deleterious variant in the ALKBH8 gene and additional clinical features that were not reported with this condition have been reported.
Synthesis of 2‐(β‐Trifluoromethyl‐β‐arylethylthio)pyridine through DBU‐Mediated Regioselective Addition of Pyridine‐2(1H)‐thione Onto α‐(Trifluoromethyl)styrenes
Authors: Zheng Pai , Deng Yupian , He Jingjing , Sun Zhudi , Liu Ying , Fan Xutong , Cao Song 
Published: January 2024

AbstractAn efficient and practical method for the synthesis of (β‐trifluoromethyl‐β‐aryl)ethyl 2‐pyridyl thioethers via hydrothiolation of α‐(trifluoromethyl)styrenes with pyridine‐2(1H)‐thione was reported. The reaction proceeded smoothly and regioselectively in an anti‐Markovnikov manner with the assistance of DBU and afforded a variety of trifluoromethyl‐containing 2‐pyridyl thioethers in moderate to good yields.
Intramolecular Carboamination of Aminodienes to N‐Heterocycles via C−N Bond Activation
Authors: Yan Xuyang , Yu Bangkui , Liu Hongchi , Huang Hanmin 
Published: January 2024

AbstractThe catalytic transformation of ubiquitous but inert C−N bonds is highly appealing in synthetic chemistry, but the efficient cleaving inert C−N bond and simultaneous incorporation of both the cleaved C‐moiety and N‐moiety into the desired products has been a long‐standing formidable challenge so far. Here, we developed a radical‐addition triggered cyclization and C−N bond cleavage process enabled by the unique I2/Ni or benzyl halide/Ni‐catalytic system, allowing the formal insertion of diene into the inert C−N bond. This reaction features high atom economy and enables an expedient annulative carboamination of aminodienes to diverse pyrrolidines, piperidines, and tetrahydroisoquinolines. Mechanistic studies have revealed that the reaction is initiated via the generation of a benzyl radical and the formation of quaternary ammonium salt is key for the C−N bond cleavage.
Stabilizing *CO2 Intermediates at the Acidic Interface using Molecularly Dispersed Cobalt Phthalocyanine as Catalysts for CO2 Reduction
Authors: Feng Shijia , Wang Xiaojun , Cheng Dongfang , Luo Yao , Shen Mengxin , Wang Jingyang , Zhao Wei , Fang Susu , Zheng Hongzhi , Ji Liyao , Zhang Xing , Xu Weigao , Liang Yongye , Sautet Philippe , Zhu Jia 
Published: January 2024

AbstractCO2 electroreduction (CO2R) operating in acidic media circumvents the problems of carbonate formation and CO2 crossover in neutral/alkaline electrolyzers. Alkali cations have been universally recognized as indispensable components for acidic CO2R, while they cause the inevitable issue of salt precipitation. It is therefore desirable to realize alkali‐cation‐free CO2R in pure acid. However, without alkali cations, stabilizing *CO2 intermediates by catalyst itself at the acidic interface poses as a challenge. Herein, we first demonstrate that a carbon nanotube‐supported molecularly dispersed cobalt phthalocyanine (CoPc@CNT) catalyst provides the Co single‐atom active site with energetically localized d states to strengthen the adsorbate‐surface interactions, which stabilizes *CO2 intermediates at the acidic interface (pH=1). As a result, we realize CO2 conversion to CO in pure acid with a faradaic efficiency of 60 % at pH=2 in flow cell. Furthermore, CO2 is successfully converted in cation exchanged membrane‐based electrode assembly with a faradaic efficiency of 73 %. For CoPc@CNT, acidic conditions also promote the intrinsic activity of CO2R compared to alkaline conditions, since the potential‐limiting step, *CO2 to *COOH, is pH‐dependent. This work provides a new understanding for the stabilization of reaction intermediates and facilitates the designs of catalysts and devices for acidic CO2R.
Competitive Coordination Structure Regulation in Deep Eutectic Electrolyte for Stable Zinc Batteries
Authors: Deng Wenjing , Deng Zhiping , Chen Yimei , Feng Renfei , Wang Xiaolei 
Published: January 2024

AbstractRechargeable zinc‐based batteries are finding their niche in energy storage applications where cost, safety, scalability matter, yet they are plagued by rapid performance degradation due to the lack of suitable electrolytes to stabilize Zn anode. Herein, we report a competitive coordination structure to form unique quaternary hydrated eutectic electrolyte with ligand‐cation‐anion cluster. Unraveled by experiment and calculation results, the competing component can enter initial primary coordination shell of Zn2+ ion, partially substituting Lewis basic eutectic ligands and reinforcing cation‐anion interaction. The hydration‐deficient complexes induced between competing eutectic as hydrogen bond donor‐accepter and water also broaden the electrochemical window and confine free water activity. The altered coordination further leads to robust hybrid organic‐inorganic enriched solid electrolyte interphase, enabling passivated surface and suppressed dendrite growth. Noticeably, stable Zn plating/stripping for 8000 cycles with high Coulombic efficiencies of 99.6 % and long cycling life of 10000 cycles for Zn‐organic batteries are obtained. Even under harsh conditions (small N/P ratio, low temperature), the profits brought by the competitive eutectic electrolyte are still very prominent. This design principle leveraged by eutectic electrolytes with competitive coordination offers a new approach to improve battery performance.
Influence of ionomer concentration and membrane thickness on membrane electrode assembly in alkaline fuel cell performance
Authors: Saidin Nur Ubaidah , Jehan Omar Syah , Leong Kok Seng , Choo Thye Foo , Wong Wai Yin , Loh Kee Shyuan , Yunus Rozan Mohamad 
Published: January 2024

AbstractThe alkaline fuel cell is subject to extensive research owing to its fast kinetic response relative to acidic media. However, the efficiency of the catalytic layer at the electrodes depends on the amount and distribution of ionomers present there. It is crucial to have the right ionomer concentration to have the best cell performance. Additionally, the membrane thickness is a significant parameter that affects the system performance in alkaline fuel cells. This research studies the best alkaline fuel cell performance using the membrane electrode assembly preparation parameters. The prepared membrane electrode assembly consists of catalyst layers containing Fumion, a commercial anion exchange ionomer, as a binding agent, sandwiched a Fumasep, a well‐known commercial anion exchange membrane. This work elucidates the single‐cell alkaline fuel cell performance by quantifying the influence of Fumion concentrations (~20–60 wt.%) within the catalytic layer and Fumasep thicknesses (30, 75 and 130 μm). The best concentration of Fumion was found to be 50 wt.%, culminating in the maximum peak power density of 67 mW cm−2 achieved by the FAA‐3‐PK‐75. Meanwhile, FAA‐3‐PK‐130 exhibited the highest open‐circuit potential with lowest power density at 53 mW cm−2. These findings may serve as a valuable guide for membrane electrode assembly preparation in alkaline fuel cells.
Socio‐technical issues in the platform‐mediated gig economy: A systematic literature review: An Annual Review of Information Science and Technology (ARIST) paper
Authors: Dedema Meredith , Rosenbaum Howard 
Published: January 2024

AbstractThe gig economy and gig work have grown quickly in recent years and have drawn much attention from researchers in different fields. Because the platform mediated gig economy is a relatively new phenomenon, studies have produced a range of interesting findings; of interest here are the socio‐technical issues that this work has surfaced. This systematic literature review (SLR) provides a snapshot of a range of socio‐technical issues raised in the last 12 years of literature focused on the platform mediated gig economy. Based on a sample of 515 papers gathered from nine databases in multiple disciplines, 132 were coded that specifically studied the gig economy, gig work, and gig workers. Three main socio‐technical themes were identified: (1) the digital workplace, which includes information infrastructure and digital labor that are related to the nature of gig work and the user agency; (2) algorithmic management, which includes platform governance, performance management, information asymmetry, power asymmetry, and system manipulation, relying on a diverse set of technological tools including algorithms and big data analytics; (3) ethical design, as a relevant value set that gig workers expect from the platform, which includes trust, fairness, equality, privacy, and transparency. A social informatics perspective is used to rethink the relationship between gig workers and platforms, extract the socio‐technical issues noted in prior research, and discuss the underexplored aspects of the platform mediated gig economy. The results draw attention to understudied yet critically important socio‐technical issues in the gig economy that suggest short‐ and long‐term opportunities for future research directions.