bluuebunny/crossref_metadata_2025_split huggingface dataset:
Continuous or interrupted pledgeted suture technique in stented bioprosthetic aortic valve replacement: A comparison of in-hospital outcomes
Authors: Arabkhani Bardia , Gonthier Sebastien , Deschamps Samuel , Jahanyar Jama , Boute Marin , Vancrayenest David , Mastrobuoni Stefano , Khoury Gebrine El , de Kerchove Laurent 
Published: November 2023

Abstract
Background
There is ambiguity in the literature regarding the continuous suture technique (CST) for aortic valve replacement (AVR). At our center, there has been a gradual shift towards CST over the interrupted pledgeted technique (IPT). This study aims at comparing outcomes for both techniques.
Methods
We performed a retrospective analysis of a single-center study of patients undergoing AVR between January 2011 and July 2020. Patients were divided into two groups: Continuous suture technique and interrupted pledget-reinforced sutures. The pre-operative and In-hospital clinical characteristics and echocardiographic hemodynamics (i.e. transvalvular gradients and paravalvular leakage) were compared between CST and IPT.
Results
We compared 791 patients with CST to 568 patients with IPT (median age: 73 and 74 years, respectively, p = 0.02). In CST there were 35% concomitant procedure vs 31% in IPT (p = 0.16). Early mortality was 3.2% in CST versus 4.8% in IPT (p = 0.15), and a second cross-clamp due to a paravalvular-leak in 0.5% vs. 1.2%, respectively (p = 0.22). The CST was not associated with new-onset conduction-blocks mandating pacemaker implants(OR 1.07, 95% CI 0.54–2.14; P = 0.85). The postoperative gradients on echocardiography were lower in CST compared to IPT, especially in smaller annuli (peak gradients: 15.7mmHg vs 20.5mmHg, in valve size < 23mm, p < 0.001)
Conclusions
The continuous suture technique was associated with lower postoperative gradients and shorter cross-clamp time compared to interrupted pledgeted technique. Differences in paravalvular leaks were non-significant, although slightly less in the continuous suture technique. There were no further differences in valve-related complications. Hence, continues suture technique is safe, with better hemodynamics compared to the interrupted pledgeted technique. This may be of clinical importance, especially in smaller size annular size.
Causal association total bilirubin and albumin levels with lung cancer risk: a mendelian randomization study
Authors: Li Qian 
Published: November 2023

AbstractOur study aim was to examine the causal effect between levels of Total Bilirubin and Albumin and the risk of developing lung cancer (LC). Previous observational studies have suggested that these two biomarkers may have anti-oxidative properties that could potentially inhibit cancer development. However, the existing evidence regarding the association between Total Bilirubin and Albumin levels and LC risk has been inconsistent. To address this, we conducted a two sample Mendelian randomization(TSMR) study to further investigate this association and assess causality. As the exposure, we utilized the publicly accessible summary statistics datasets of genome-wide association studies (GWAS) for bilirubin and albumin. The outcome, in this case, was a GWAS for lung cancer.Our results indicate that bilirubin and albumin levels may be causally associated with an increased risk of LC.[bilirubin:odds ratio (OR) = 1.341%, confidence interval (CI): 1.076–1.672, P= 0.009;albumin: OR=1.582%, CI:1.077-2.323,P = 0.019].
ATI-driven SAR Remote Collaboration Platform for Manufacturing in a Training Task
Authors: Li Xiuling , Zhang Ruikun , Li Fusheng , Yue Limin , Wang Peng , Yang Huan 
Published: November 2023

Abstract
Global events such as pandemics and wars have prompted many individuals to reassess the significance of remote collaboration for training, providing assistance, maintenance, and education. While video conferencing has gained popularity, numerous opportunities still exist for more sophisticated methods of Augmented Reality (AR) remote interaction. Hand-drawn AR sketches/annotations (AAS) are commonly used for expressing visual instructions. However, these freehand drawings are not enough to communicate the specific instructions required for industrial applications. Therefore, oral communication always serves as a critical supplement for addressing misinterpretations and language barriers. In such cases, our work is dedicated to sharing clear instructions based on AAS by the adaptive transformation of instructions (ATI) method. As a result, we present a Spatial AR(SAR) remote collaborative platform that can support converting AAS into standard symbols which provides clear guidance and has been widely accepted by the public. We conduct a formal user study to evaluate the prototype platform concerning performance time, general collaborative experience, usability based on ranking, and users’ preferences. The results indicated that ATI-based cues have a positive rule on remote collaborative training tasks in terms of user experience. More significantly, our work provides valuable implications on the way for further study of gesture-based interaction in AR remote collaboration on training tasks.
Methyl jasmonate application downregulates red drupelet reversion by modulating the antioxidant potential and maintains fruit quality of ‘Elvira’ blackberries
Authors: Shah Hafiz Muhammad Shoaib , Singh Zora , Hasan Mahmood Ul , Kaur Jashanpreet , Afrifa-Yamoah Eben , Woodward Andrew 
Published: November 2023

Abstract
Red drupelet reversion (RDR) shortens the marketing window for blackberries by reducing cosmetic appearance of the fruit. Blackberry plants were sprayed with methyl jasmonate (MJ 0, 1, 2 or 3 mM), two weeks before tentative harvest maturity, to evaluate effects on RDR, antioxidant capacity and fruit quality in cold stored blackberry fruit for up to 12 days. MJ significantly reduced RDR while maintaining higher anthocyanins, phenolics and flavonoids during cold storage for 12 days. Fruit treated with 1 mM MJ showed higher total antioxidants, ascorbic acid, and glutathione content. Additionally, MJ treated raspberries displayed higher activities of superoxide dismutase, catalase, ascorbate oxidase, monodehydroascorbate reductase, dehydroascorbate reductase and glutathione reductase enzymes, than controls for 12 days. In conclusion, the preharvest spray application of MJ (1 mM) has the potential to reduce RDR, improve antioxidant capacity and maintain fruit quality of cold stored blackberries.
Role of conventional dynamic contrast-enhanced MRI and ultrafast MRI in breast cancer patients receiving neoadjuvant chemotherapy: prediction of pathologic complete response and radiopathologic correlation using microvessel density
Authors: Choi Sung-Eun , PARK Ah Young , Kim Gwang Il , Jung Hae Kyoung , Ko Kyung Hee , Kim Yunju 
Published: November 2023

Abstract
Background
We investigated the potential of ultrafast MRI and conventional dynamic contrast-enhanced MRI (DCE-MRI) in predicting pathologic complete response (pCR) after neoadjuvant chemotherapy (NAC) in breast cancer patients and correlated the kinetic MRI parameters with histologic microvessel density (MVD).
Methods
We retrospectively analyzed 61 breast cancer patients who underwent NAC and surgery between August 2020 and August 2022. Ultrafast and conventional DCE-MRI features and pathologic results were compared between pCR and non-pCR group. Logistic regression analysis was performed to identify predictive factors for pCR. MRI kinetic parameters were correlated with histologic MVD.
Results
Seventeen out of 61 patients achieved pCR (27.9%). Significant differences were observed in tumor size, axillary lymph node metastasis, delayed washout component, angiovolume, and molecular subtype between pCR and non-pCR groups. Tumor size (odds ratio [OR] = .875, p = .02), axillary lymph node metastasis (OR = .032, p = .01), and HER2-enriched or triple-negative cancer types (OR = 47.530 or 751.991, p = .003 or .006) were independent predictive factors for pCR. In HER2-enriched cancer, low initial enhancement value and angiovolume were associated with pCR (p = .04). Ultrafast MRI parameters were not predictive of pCR, but maximum slope was higher in high MVD group compared to low MVD group (68.6%/sec ± 50.3 vs 40.4%/sec ± 39.3, p = .049).
Conclusion
Tumor size, axillary lymph node status, molecular subtypes were predictive factors for pCR in breast cancer, but ultrafast MRI parameters were not. Maximum slope on ultrafast MRI can reflect histologic MVD.
mbDecoda: A debiased approach to compositional data analysis for microbiome surveys
Authors: Zong Yuxuan , Zhao Hongyu , Wang Tao 
Published: November 2023

Abstract

Background: Microbiome research aims to identify microbes that play crucial roles in both health and disease, with the potential of these microbes to serve as biomarkers for preventing, diagnosing, and treating diseases. However, the presence of compositionality, sparsity, and over-dispersion presents formidable challenges for absolute abundance analysis, leading to potentially misleading results when classical data analysis methods are applied.
Results: To address these challenges, we introduced mbDecoda, a model-based approach for debiased analysis of sparse compositions of microbiomes. mbDecoda employs a zero-inflated negative binomial model, linking mean abundance to the variable of interest through a log link function, and it accommodates the adjustment for confounding factors. Through extensive simulation studies and analysis of real-world microbiome datasets, we demonstrated that mbDecoda compared favorably to state-of-the-art methods in terms of effectiveness, robustness, and reproducibility.
Conclusions: mbDecoda is an accurate and reliable method for absolute abundance analysis. It is expected to be a valuable contribution to the statistical toolbox for for analyzing and interpreting microbiome data.
Understanding the Relationship Between Neutrophil Function and Demographic Variables
Authors: Hickman Elise , Rebuli Meghan E. , Robinette Carole , Jaspers Ilona 
Published: November 2023

Abstract

Neutrophils play a crucial role in the body's defense against respiratory pathogens, and dysregulation is linked to airway diseases. The study presented here explores the association between demographic factors (age, BMI, and sex) and functional phenotypes (oxidative burst and bioenergetics) of neutrophils. We measured PMA-stimulated oxidative burst (Seahorse XF) and phagocytosis (pHrodo red S. aureus) of human peripheral blood neutrophils and determined whether there were significant demographic associations with cellular function. There were no significant associations between neutrophil oxidative burst bioenergetic parameters or phagocytosis and BMI or age. However, our data revealed sexual dimorphism in neutrophil phagocytosis, with males exhibiting significantly higher phagocytic capacity than females. Additionally, phagocytic capacity and bioenergetic parameters were correlated in males but not in females. The study indicates potential variations in neutrophil activation pathways between males and female and emphasizes the importance of considering sex as a biological variable in respiratory host defense research.
Emergent collective motion of self-propelled condensate droplets
Authors: Lin Marcus , Kim Philseok , Arunachalam Sankara , Hardian Rifan , Adera Solomon , Aizenberg Joanna , Yao Xi , Daniel Dan 
Published: November 2023

Abstract
Recently, there is much interest in droplet condensation on soft or liquid/liquid-like substrates. Droplets can deform soft and liquid interfaces resulting in a wealth of phenomena not observed on hard, solid surfaces (e.g., increased nucleation, inter-droplet attraction). Here, we describe a unique complex collective motion of condensate water droplets that emerges spontaneously when a solid substrate is covered with a thin oil film. Droplets move first in a serpentine, self-avoiding fashion before transitioning to circular motions. We show that this self-propulsion (with speeds in the 0.1–1 mm s−1 range) is fuelled by the interfacial energy release upon merging with newly condensed but much smaller droplets. The resultant collective motion spans multiple length scales from submillimetre to several centimetres, with potentially important heat-transfer and water-harvesting applications.
The vegetation characteristics of Pinus taiwanensis drive the changes in different components of soil respiration in Wuyi Mountain, Southeast China
Authors: Sun Jun , Li Jilong , Penuelas Josep , Sardans Jordi , Hu Dandan , Zhong Quanlin , Cheng Dongliang 
Published: November 2023

Abstract
Background and Aims
Many driving variables have been used to model different soil respiration components. However, large uncertainty exists in the annual fluxes of soil respiration related to vegetation characteristics and soil properties.
Methods
Here, five Pinus taiwanensis forests along different elevations in the Wuyi Mountain were used to explore how the annual fluxes of total soil respiration (RS), autotrophic respiration (RA), and heterotrophic respiration (RH) were regulated by vegetation characteristics, including vegetation carbon sequestration (Vco2), 0-20 cm root biomass (WR), litter production (PL), leaf area index (LAI), and also soil properties, including soil temperature (ST), soil moisture (SM), fungal PLFAs and bacterial PLFAs.
Results
The results indicate that (1) the RH was positively correlated with ST, PL, WR, and LAI, and negatively correlated with SM; and the RA was positively related to the Vco2 and LAI, and inversely correlated with fungal and bacterial PLFAs. (2) RH is mainly determined by WR, while RA can be comprehensively predicted through the Vco2, and LAI; besides, the redundancy analysis indicated that WR, Vco2, and LAI together explained 83.06% of RS, RH, and RA changes in different elevations.
Conclusion
Overall, our results suggested that vegetation characteristics attributes such as WR, Vco2, and LAI rather than soil properties and microbial community composition, were more important for explaining the annual fluxes of soil respiration components variance in five P. taiwanensis forests. Thus, soil respiration depends more on the plant capacity to fix organic carbon as an initial source of organic matter sustaining overall soil respiration.
Estimation of Spatio-Temporal Near Surface Air Temperature from Land Surface Temperature (LST) Generated by Landsat 8 Satellite Data
Authors: KARAKUŞ Nihat , SELİM Serdar , DÖNMEZ Burçin , KILÇIK Ali 
Published: November 2023

Abstract
Predicting air temperature with high accuracy is useful for many agricultural, environmental, hydrological, and ecological applications, especially for global climate change studies. Air temperature is traditionally obtained from measurements at mobile or stationary meteorological stations and their distribution is determined by applying various interpolation methods. However, using of these data is limited and insufficient in regions such as Türkiye where the spatial distribution of stations is limited, containing many micro-climatic regions, and where the air temperature is very important, especially for agricultural applications. In this respect, being able to predict the near-surface air temperature with high accuracy with satellite-based observations constitutes the motivation of this study. Many studies tried to estimate air temperature using surface temperature data. However, the obtained accuracies were limited as medium or low-resolution satellite data were used and varied according to the regions. The aim of this study is to predict the land surface temperature and air temperature with high accuracy to be produced from high spatial resolution Landsat 8 images. For this purpose, two data sets were used, namely the LST data obtained from Landsat 8 and the air temperature data measured with the meteorological station. Linear regression models were created by comparing these two data sets and Pearson correlation was applied to determine the correlation between them. The results showed that there was a significant relationship between the produced LST and the predicted air temperature for all stations, this relationship was estimated in the 95% standard deviation range, and the difference between the two values was mostly below 1°C. This result showed that the applied method is suitable for estimating the air temperature near the surface. It has been observed that this method can be used with high accuracy, especially in regions with insufficient number of meteorological stations, variable air temperatures in short distances, and different altitudes.
Galangin cooperates with oxaliplatin to inhibit the proliferation and invasion of colorectal cancer cells by targeting CBX3
Authors: Chu Bowei , Lou Yuanmei , Yu Qifeng 
Published: November 2023

Abstract
Objective
Examining the potential mechanism underlying the effect of galangin combined with oxaliplatin on the invasion and proliferation of colorectal cancer.
Methods
The effects of galangin combined with oxaliplatin on colorectal cancer (CRC) cell invasion and proliferation were assessed using CCK8 and Transwell assays. Using WB and qPCR, the expression of CBX3 in several CRC cell lines was identified. The levels of CBX3 in normal colorectal tissues and CRC tissues were compared using HPA and GEPIA, and the impact of CBX3 on the prognosis of CRC patients was investigated using GEPIA. To determine whether galangin targets CBX3 to influence the growth and invasion of CRC cells, cell assays were employed. The levels of ROS in HCT116 were measured by immunofluorescence following galangin treatment. The impact of CBX3 on immune cell infiltration in CRC was examined using TIMER. GEPIA produced a list of CBX3-related genes, and R was utilized to perform GO/KEGG enrichment analysis.
Results
We found that galangin combined with oxaliplatin inhibited the proliferation and invasion of CRC cells and down-regulated the expression of CBX3, which was rescued by overexpression of CBX3. DFS was shorter in those with elevated CBX3 expression. The level of ROS in HCT116 was significantly increased after galangin treatment. The invasion of CD8 + T cells and macrophages in the immunological microenvironment of CRC is favorably linked with increased expression of CBX3. Nuclear chromatin, histone binding, and covalent chromatin modification are enriched regions in CBX3 and related genes.
Conclusion
Galangin combine with oxaliplatin can inhibit the proliferation and invasion of colorectal cancer cells by down-regulating the expression of CBX3, and CBX3 is highly expressed in colorectal cancer and is related to short DFS.
Effect of cereal-legume intercropping on advance soil nutriments under semi-arid climate
Authors: Attallah Amal , hamdi wissem , Souid Amira , Farissi Mohamed , l'taif boulbaba , Zagrarni Mohamed Faouazi 
Published: November 2023

Abstract
Intercropping is known to improve the available resource usage and increase yield compared to sole cropping. Field experiments were carried out in 2020-2021 (EXP-A) and 2021-2022 (EXP-B) in Medenine, Tunisia, to compare at the flowering stage of plant growth, the agronomic performance of cereals (durum wheat) intercropped with a legume (chickpea) to their monoculture and to the soil bulk such as microbial mass C and N, nitrogen nutrition, and carbon availability. In this study, we found no significant differences between the proportions of Ntot for sole or intercropped Chickpea, with a difference of 4 and 6% for two seasons of culture (2020-2021 and 2021-2022). On the other hand, durum wheat grown in intercrops (DuWh-IR) significantly (p<0.05) acquired more Ntot than durum wheat grown in mono-crops (DuWh-MC) with an augmentation of 20% in 2020-2021 and 18% in 2021-2022. At the same time, the N concentration of durum wheat roots increases significantly under the effect of intercropping with 20% in 2020-2021 and 28% in 2021-2022. However, it is noted that the N content for chickpeas was comparatively lower for the intercrops as compared to sales crops i.e., eight percent in the years 2020 to 2021 and seven percent in the year 2021 to 2022, for both the shoots. In semi-arid regions of Southern Tunisia, cereals-legumes (Chickpea-Durum wheat) intercropping can influence the N and C soil fertility, which improves crop production while respecting the environment by reducing the use of nitrogen fertilizers.
Effect of the cereal-legume intercropping on Phosphatases and Phytase activity under alkaline soil.
Authors: Souid Amira , hamdi wissem , Attallah Amal , Farissi Mohamed , l'taif boulbaba , Zagrarni Mohamed Faouazi 
Published: November 2023

Abstract

The purpose of the study is to evaluate the effectiveness of intercropping systems cereals (Durum/hard Wheat)-legume (Cicer arietinum) on phosphorus (P) acquisition, pH soil variation, and the variation in enzymatic activity, through root-induced processes in semi-arid soil of South Tunisia. Split plot experiments with triplicate repetitions were carried out in southern Tunisia during two years of field (2020–2021 and 2021–2022). These comprise mono-crop chickpea (CK) and mono-crop durum wheat/ wheat durum (DW/WD), durum wheat intercropping (DW-C), and chickpea intercropping (CK-C). At the complete vegetation stage of durum wheat and chickpea, three soil samples were carried in layer surface for each experimental plot. For the analyses of soil, the P total, Olsen-P, phytase, acid phosphatases, and pH were carried out in the experiment. The obtained findings show a significant amelioration in P total contents in DW-C by 28% and 26% to DW, and 94% and 93% than BS during the two years of field experiment (2020–2021 and 2021–2022) respectively. Furthermore, the Study reported an increase of Olsen-P in the rhizosphere of DW-C by around 5%, 42% than DW, and 36%, 65% to bulk soil (BS) during the two-year experiment. Likewise, these results revealed an increase in A-Phase rates in the DW-C rhizosphere during the two agricultural seasons (2020–2021 and 2021–2021), of approximately 26%, 8% than DW and 33%, 67% than BS respectively. As well as the phytase activity indicated an increase in the DW-C rhizosphere by 67% and 69% than in BS and only by 8% and 7% than in DW for the two seasons (2020–2021 and 2021–2021). Indeed, the rhizosphere acidification of rhizosphere was found very much high in CK-C (0.63 pH units and 0.55 units lower than in the BS).