bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effectiveness of Interventions to Improve Coping and Resilience of Frontline Mental Healthcare Professionals Towards Workplace Violence on Psychiatric Wards—A Systematic Review
Authors: Doedens Paul , Kiel‐Clayton Laura M. , Daams Joost G. , de Haan Lieuwe 
Published: February 2025

ABSTRACTWorkplace violence (WPV) is a harmful phenomenon happening in psychiatric wards. Despite preventive efforts, mental health services cannot eliminate WPV. If mental health services can increase the coping and resilience of frontline mental healthcare professionals (FMHPs) towards WPV, it could contribute to their mental health and well‐being. To perform a systematic review of comparative studies on interventions to improve coping and resilience towards WPV aimed at FMHPs working in psychiatric wards. Systematic review on comparative intervention studies, with electronic searches in MEDLINE, Embase, Cochrane CENTRAL, PsycINFO and CINAHL. We registered our protocol in PROSPERO (CRD42022373757). Performing a meta‐analysis seemed not to be feasible, so we provided a narrative summary of the included studies, methodological quality and results. We included nine studies, with interventions focused on positive behavioural support, resilience enhancement and aggression management training. Most studies reported positive effects, though with a moderate to high risk of bias. Positive behavioural support, biofeedback and aggression management training are promising interventions in our review. Biofeedback interventions and positive behavioural support could be valuable additions to existing training programmes to improve coping and resilience. Future studies should focus on demonstrating the robustness of effects, the mechanism of increasing coping and resilience regarding WPV and the development and implementation of effective interventions.
Effectiveness of Physical Activity Interventions on Acute Inpatient Mental Health Units on Health Outcomes: A Systematic Review
Authors: Graham Michael , Hodgson Philip , Fleming Laura , Innerd Alison , Clibbens Nicola , Hope Wendy , Aston Luke , Glascott Michelle 
Published: February 2025

ABSTRACTPhysical activity has been shown to improve outcomes across a range of physical and mental health conditions as an adjunct or standalone intervention for many mental disorders. The outcome and effectiveness of physical activity in acute mental health units are less well understood. Systematic searches were completed in three databases (CINAHL, MEDLINE, and PsycINFO). Eligible studies were published between March 2013 and February 2024, included a physical activity intervention for inpatients on acute mental health units, and reported primary quantitative, qualitative, or mixed methods data for patients between 18 and 65 years of age. Participants must have had a primary diagnosis of a mental health condition with or without physical comorbidities. Data extracted included reported components of the interventions and individual health outcomes. Methodological quality and risk of bias was assessed using the mixed methods appraisal tool and cochrane risk of bias tools for randomised and non‐randomised controlled trials. Twelve studies were identified for review (combined sample size of 560). Seven studies reported improvements in mental health outcomes, and two reported improvements in physical health outcomes in favour of the intervention group. There was a large variation between intervention characteristics and clarity in reporting. Assessment and measurement of outcomes contributed to a high risk of bias among included studies due largely to self‐assessment. Physical activity interventions on AMHUs have the potential to contribute to improvements in mental and physical wellbeing beyond that experienced from usual treatment practices (e.g., medication). However, further work is needed in the specific context of acute mental health units regarding the development and evaluation of physical activity interventions.
Perceptions, Contagion, and Civil Unrest
Authors: Abi‐Nassif Christophe , Islam Asif Mohammed , Lederman Daniel 
Published: February 2025

ABSTRACTThis paper investigates the impact of citizens' perceptions of economic and political conditions on nonviolent uprisings. For a global sample of high‐income (Europe) and developing economies (Sub‐Saharan Africa, South Asia, East Asia and the Pacific, Latin America, and Middle East and North Africa), on average, negative perceptions of political conditions have a significant positive effect on the number of anti‐government protests and general strikes while negative perceptions of economic conditions do not, even after accounting for actual economic conditions and the quality of governance. This holds for European and high‐income countries but not for developing economies where both economic and political perceptions matter. The international contagion of protests attenuates this regional heterogeneity, possibly implying that in Europe, the incidence of uprisings in nearby countries tends to generate protests at home through its effect on political perceptions. This invites the possibility of countries perennially facing vicious cycles of protests. Overall, the effects of political perceptions and protest contagion are robust to the inclusion of numerous control variables, seemingly valid instrumental variables, alternative count‐data estimators, and sample composition.
Improving neurodiversity awareness in school students: a scoping review protocol
Authors: Hiremath Mandira , Freeman Nerelie , Al-Shawsh Mohammed , Ure Alexandra 
Published: February 2025

Objective:
This scoping review aims to map and characterize existing programs present in mainstream schools internationally that are targeted at improving children’s awareness about neurodiversity.

Introduction:

Neurodiversity is a term used to describe human neurocognitive heterogeneity. Increased understanding and awareness about neurodiversity among school students has the potential to improve general student health and well-being. However, there is currently no standardized approach to raising children’s awareness about neurodiversity in schools and the associated literature is diffuse.

Inclusion criteria:
Literature will be included if it describes and/or evaluates programs designed to be delivered in mainstream schools aimed at increasing awareness of neurodiversity among students aged 5 to 18 years, regardless of geographical location. Published, unpublished, and gray literature from 2013 to the present will be considered.

Methods:
An academic literature search will be conducted across 5 databases: MEDLINE, CINAHL, PsycINFO, Embase, and ERIC. A gray literature search will also be performed across sources including ProQuest and Google Scholar, as well as targeted websites, expert opinion, and reference lists of relevant peer-reviewed literature. Articles will be selected based on eligibility criteria. Data extraction will be conducted independently by 2 extractors using a pre-determined form documenting study methods, population, interventions, and outcomes. Analysis and presentation of results will be reported according to the study objectives.

Review registration:
Open Science Framework https://osf.io/6b378
Microscopic Spray Characteristics of Dimethyl Ether and Diesel in Ambient Conditions
Authors: Agarwal Avinash Kumar , Kumar Vikram , Mehra Shanti , Valera Hardikk 
Published: February 2025

Abstract
A spray study is essential to understand the combustion and emissions from internal combustion engines (ICEs). It supports engine performance optimization and tailpipe emission reduction. The characteristics of the fuel spray determine the fuel–air mixing and essential requirements for efficient combustion. Thus, fuel spray characterization is necessary to understand the spray atomization and droplet velocity. Fuel properties, ambient conditions, fuel injection pressure, and injector nozzle design influence the spray characteristics. This experimental study used a mechanical injector to perform a comparative analysis of the microscopic spray characterization for dimethyl ether (DME) and diesel at fixed injection pressure and ambient conditions. Spray characterization was performed inside a constant volume spray chamber (CVSC) to assess spray droplet velocity and size distributions using a phase Doppler interferometer (PDI). Results showed that the DME spray droplet sizes were smaller than diesel due to differences in test fuel properties such as surface tension and viscosity. The number of smaller droplets in DME spray surpassed the numbers for diesel. This study showed that DME spray has exceptional evaporation/atomization properties, enhancing the fuel–air mixture's homogeneity, which improves the combustion, performance, and emissions of DME-fueled engines.
Multi-objective prediction of energy consumption of steam turbine system based on 660MW ultra-supercritical coal-fired unit
Authors: Wang Qiwei , Ma Xiaojing , Yu Kaifeng , Kari Tusongjiang 
Published: February 2025

Abstract
This study is aimed at the issue of energy waste resulting from significant fluctuations in the energy consumption of steam turbine system under the flexible peaking demands of coal-fired units. To accurately predict the energy consumption of these units across a wide range of load conditions, the energy consumption prediction model of eXtreme Gradient Boosting (XGBoost) steam turbine system is established. Firstly, the model variables are chosen based on the existing measurements and an analysis of the power plant. Meanwhile, the energy consumption dataset and its distribution are calculated by the Consumption Rate Analysis (CRA). Secondly, the model feature variables are screened by the Maximum Information Coefficient (MIC) and Kendall rank correlation coefficient, and the energy consumption prediction model of 660 MW steam turbine system based on XGBoost is established. Finally, the Bayesian Optimization (BO) algorithm is employed to determine the best hyperparameters of XGBoost model. Moreover, three energy consumption prediction models of MIC-BO-XGBoost are built for multi-objective prediction: independent modeling, chain modeling 1, and chain modeling 2. Chain modeling 2 is capable of forecasting the energy consumption of the steam turbine system in ultra-supercritical coal-fired units with greater precision under wide variations of load. It can provide the basis for the operation optimization of steam turbine system of subsequent coal-fired units.
Amplicon sequencing and culture-dependent approaches reveal core bacterial endophytes aiding freezing stress tolerance in alpine Rosaceae plants
Authors: Marian Malek , Antonielli Livio , Pertot Ilaria , Perazzolli Michele 
Published: February 2025

ABSTRACT

Wild plants growing in alpine regions are associated with endophytic microbial communities that may support plant growth and survival under cold conditions. The structure and function of endophytic bacterial communities were characterized in flowers, leaves, and roots of three alpine Rosaceae plants in Alpine areas using a combined amplicon sequencing and culture-dependent approaches to determine the role of core taxa on plant freezing stress tolerance. Amplicon sequencing analysis revealed that plant tissue, collection site, and host plant are the main factors affecting the richness, diversity, and taxonomic structure of endophytic bacterial communities in alpine Rosaceae plants. Core endophytic bacterial taxa were identified as 31 amplicon sequence variants highly prevalent across all plant tissues. Psychrotolerant bacterial endophytes belonging to the core taxa of
Duganella
,
Erwinia
,
Pseudomonas
, and
Rhizobium
genera mitigated freezing stress in strawberry plants, demonstrating the beneficial role of endophytic bacterial communities and their potential use for cold stress mitigation in agriculture.

IMPORTANCE

Freezing stress is one of the major abiotic stresses affecting fruit production in Rosaceae crops. Current strategies to reduce freezing damage include physical and chemical methods, which have several limitations in terms of costs, efficacy, feasibility, and environmental impacts. The use or manipulation of plant-associated microbial communities was proposed as a promising sustainable approach to alleviate cold stress in crops, but no information is available on the possible mitigation of freezing stress in Rosaceae plants. A combination of amplicon sequencing, culture-dependent, and plant bioassay approaches revealed the beneficial role of the endophytic bacterial communities in alpine Rosaceae plants. In particular, we showed that culturable psychrotolerant bacterial endophytes belonging to the core taxa of
Duganella
,
Erwinia
,
Pseudomonas
, and
Rhizobium
genera can mitigate freezing stress on strawberry seedlings. Overall, this study demonstrates the potential use of psychrotolerant bacterial endophytes for the development of biostimulants for cold stress mitigation in agriculture.
Amplicon microbiome sequencing of compost from conventional and redesigned compost buckets
Authors: Klosko Elizabeth , Hutchison Elizabeth , Almomani Ahmad 
Published: February 2025

ABSTRACT

Here, we report using amplicon sequencing to assess microbial growth in both conventional and pyramid-shaped compost buckets. Proteobacteria and Firmicutes were the primary bacterial phyla present, and Ascomycota the primary fungal phylum present. Bucket shape did not significantly affect microbial community composition.
Complete genome sequence of chicken anemia virus from a field outbreak in Bangladesh
Authors: Akter Marjana , Hasan S. M. Nazmul , Jeba Nurejunnati , Mozumder Anandha , Mou Moslema Jahan , Araf Yusha , Mia Roni , Akter Sharmin , Salauddin Md. , Rahman Md Zaminur , Hossain Muhammad Shahdat , Saha Sukumar , Islam Tofazzal , Hossain Md. Golzar 
Published: February 2025

ABSTRACT

Chicken anemia virus (CAV) causes immunosuppression and increased mortality in chickens globally, including Bangladesh. This report provides the complete genome sequence of a CAV strain from a recent outbreak on a Bangladeshi layer farm, contributing to the limited availability of published data on the CAV genome in the country.
Refining the genome of alkylbenzene-degrading
Rhodococcus
sp. DK17 and comparative analysis with genomes of its deletion mutants
Authors: Jeon Jehyun , Kim Dockyu , Kim Eungbin , Lee Yung Mi 
Published: February 2025

ABSTRACT

Rhodococcus
sp. strain DK17 degrades various alkylbenzenes, including
o
-xylene, making it a potential biocatalyst for the production of fine chemicals. DK17 carries the degradative genes on linear mega-plasmids. Here, we present the refined DK17 genome and analyze the genetic variations in UV-induced mutants DK176 and DK180.
Complete genome sequences of 14 lytic bacteriophages against
Acinetobacter baumannii
from Kenya belonging to the genera
Obolenskvirus
and
Friunavirus
Authors: Mwai Felix , Kigen Collins , Makobe Celestine , Mutai Ivy , Georges Martin , Odoyo Erick , Gachoya Moses , Musila Lillian 
Published: February 2025

ABSTRACT

We report the genome sequences of 14
Acinetobacter
phages isolated in Kenya, belonging to the genera
Friunavirus
and
Obolenskvirus
. They have double-stranded DNA with genome sizes between 39 and 45 kb and G + C content from 38% to 39%. The genomes contain 56 to 93 predicted coding sequences.
Coexistence of
tmexCD-toprJ
,
bla
NDM-1
, and
bla
PME-1
in multi-drug-resistant
Pseudomonas juntendi
isolates recovered from stool samples
Authors: Liu Wugao , Liu Yi , Jin Jing , Wu Ningjun , Wu Weiping , Qu Chunsheng 
Published: February 2025

ABSTRACT

Pseudomonas juntendi
has received limited research attention, yet strains carrying multi-drug resistance genes pose a threat to global public health. We aimed to characterize the genome of two fecal-derived strains of
Pseudomonas juntendi
, both harboring
tmexCD-toprJ
,
bla
NDM-1
, and
bla
PME-1
on the chromosome, recovered from two patients. Average nucleotide identity (ANI) analysis showed that L4008hy and L4046hy were remarkably similar. They showed high levels of resistance to aztreonam, imipenem, ciprofloxacin, amikacin, piperacillin–tazobactam, ceftazidime–avibactam, and polymyxin B in antimicrobial susceptibility testing using agar dilution method and broth microdilution methods. Additionally, an integrative and conjugative element (ICE) similar to ICE
6660
was detected on the chromosome, which contains all resistance genes and has a relatively complete transfer module, and potential transfer mechanisms were identified. Phylogenetic analysis of
P. juntendi
reveals the genomic diversity of the species and sheds light on environmental–human transmission.

IMPORTANCE

Up to now, research on
Pseudomonas juntendi
is still very limited. Our findings suggest that
P. juntendi
commonly carries diversity resistance genes on chromosomes and is stably inherited, highlighting the need for further studies on the antimicrobial properties of this bacterium. The coexistence of
tmexCD-toprJ
,
bla
NDM-1
, and
bla
PME-1
on the chromosome in
P. juntendi
was reported for the first time. The identified integrative and conjugative element (ICE) contains all the identified resistance genes and serves as a vector for resistance gene transfer between bacteria.
P. juntendi
, which harbors multi-drug resistance genes, particularly those encoding carbapenemases, acts as a reservoir of resistance genes. Its spread in clinical settings poses additional challenges to treatment.
Immune-mediated TTP secondary to checkpoint inhibitor use in a patient with stage IV melanoma
Authors: Parekh Deevyashali , Liu Michelle , Subedi Yadu Nanda , Basnet Alina 
Published: February 2025

We describe the case of a middle-aged man with stage IV metastatic melanoma receiving ipilimumab/nivolumab combination therapy. Two weeks after receiving his third cycle of treatment, he presented to the emergency department with altered mental status, acute kidney injury, fever, anaemia with labs suggestive of haemolysis and a platelet count of 10. He had a calculated plasmic score of 6. A review of the peripheral smear confirmed the presence of schistocytes. He was treated with emergent plasma exchange, high-dose steroids, rituximab and caplacizumab throughout his hospitalisation. He had a good response to this treatment and was ultimately discharged to home 15 days later with a platelet count of greater than 200 and a high ADAMTS13 level in plasma (undetectable on admission).A growing body of literature suggests the possibility of thrombotic thrombocytopenic purpura (TTP) secondary to immunotherapy use, and thus a high index of suspicion is needed in these patients for timely, life-saving treatment initiation.
The persistence of failure in water, sanitation and hygiene programming: a qualitative study
Authors: Barrington Dani J , Sindall Rebecca C , Chinyama Annatoria , Morse Tracy , Sule May N , Beale Joanne , Kativhu Tendai , Krishnan Sneha , Luwe Kondwani , Daudi Malolo Rossanie , Mcharo Onike , Odili Anthony C , Ravndal Kristin T , Rose Jo , Shaylor Esther , Wozei Eleanor , Chikwezga Faida , Evans Barbara E 
Published: February 2025

IntroductionUnsafe water, sanitation and hygiene (WASH) causes millions of deaths and disability-adjusted life-years annually. Despite global progress towards universal WASH, much of WASH programming continues to fail to improve health outcomes or be sustainable in the longer term, consistently falling short of internal performance indicators and sometimes negatively impacting the well-being of local stakeholders. Although sector experts in high-income countries have often provided explanations for such failures, the opinions of those implementing WASH programming at the ground level are rarely published.MethodsIn 2020, we purposively recruited 108 front-line WASH professionals in Malawi, South Africa, Tanzania and Zimbabwe to participate in 96 in-depth interviews, explaining why they believe WASH failure persists. Through participatory analysis, including framework analysis with additional axial coding and member-checking of our findings, we determined the core reasons for WASH failure as perceived by participants.ResultsInterviewees reported poor engagement and commitment of intended users, unrealistic and idealistic expectations held by funders and implementers, and a general lack of workforce and financial capacity as significant contributors to WASH failure. Our analysis shows that these issues stem from WASH programming being implemented as time and budget-constrained projects. This projectisation has led to reduced accountability of funders and implementers to intended users and a focus on measuring inputs and outputs rather than outcomes and impacts. It has also placed high expectations on intended users to sustain WASH services and behaviour change after projects officially end.ConclusionsOur findings imply that WASH programming needs to move away from projectisation towards long-term investments with associated accountability to local governments and longitudinal measurements of WASH access, as well as realistic considerations of the needs, abilities and priorities of intended users. Funders need to reconsider the status quo and how adjusting their systems could support sustainable WASH services.
Insights from the NHS England Clinical Entrepreneur Programme
Authors: Holland Brown Tamsin Mary , Sullivan Polly , Sullivan Poppy 
Published: February 2025

The clinical entrepreneur programme (CEP) plays a role in supporting, reatining and empowering NHS staff by fostering innovation within the healthcare system. Established to address systemic barriers that often lead clinicans to leave the NHS to pursue entrepreneurial endeavours, the CEP enables staff to develop and implement transformative healthcare solutions while remaining within the NHS workforce. This not only benefits the innovators but strengthens the NHS by promoting a culture of continuous improvement and adaptation to emerging medical technologies.A strength of the CEP is its inclusivity of a diverse range of clinical and non-clinical staff and students. Student Selected Component (SSC) projects have also been supported cultivating digital health competencies, quality improvement awareness, research skills and translational capabilities.Beyond individual development, the CEP contributes to broader NHS transformation through initiatives such as NHS InSites and collaboration with Health Innovation Networks (HINs) and NHS Trusts, aiming to contribute to real-world adoption of solutions.With over 1000 alumni and growing, the CEP has retained and reintegrated healthcare professionals within the NHS, while supporting new innovations to reach patients. This reinforces a progressive NHS ecosystem that values and integrates clinical innovation and entrepreneurship.