bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Crohn’s Disease Exclusion Diet: A Comprehensive Review of Evidence, Implementation Strategies, Practical Guidance, and Future Directions
Authors: Sigall Boneh Rotem , Westoby Catherine , Oseran Ilan , Sarbagili-Shabat Chen , Albenberg Lindsey G , Lionetti Paolo , Manuel Navas-López Víctor , Martín-de-Carpi Javier , Yanai Henit , Maharshak Nitsan , Van Limbergen Johan , Wine Eytan 
Published: November 2023

Abstract
Dietary therapy is increasingly recognized for the management of Crohn’s disease (CD) over recent years, including the use of exclusive enteral nutrition (EEN) as first-line therapy for pediatric CD according to current guidelines. The Crohn’s disease exclusion diet (CDED) is a whole-food diet designed to reduce exposure to dietary components that are potentially pro-inflammatory, mediated by negative effects on the gut microbiota, immune response, and the intestinal barrier. The CDED has emerged as a valid alternative to EEN with cumulative evidence, including randomized controlled trials, supporting use for induction of remission and possibly maintenance in children and adults. We gathered a group of multidisciplinary experts, including pediatric and adult gastroenterologists, inflammatory bowel diseases (IBD) expert dietitians, and a psychologist to discuss the evidence, identify gaps, and provide insights into improving the use of CDED based on a comprehensive review of CDED literature and professional experience. This article reviews the management of CDED in both children and adults, long-term aspects of CDED, indications and contraindications, selecting the best candidates, identifying challenges with CDED, globalization, the role of the multidisciplinary team, especially of dietitian, and future directions. We concluded that CDED is an established dietary therapy that could serve as an alternative to EEN in many pediatric and adult cases, especially with mild to moderate disease. In severe disease, complicated phenotypes, or with extraintestinal involvement, CDED should be considered on a case-by-case basis, according to physician and dietitians’ discretion. More studies are warranted to assess the efficacy of CDED in different scenarios.
Does the Label Matter? Examining the Effects of “Vaccine Passport” Versus “Vaccine Verification” on Subsequent Audience Frames and Policy Attitudes
Authors: Hubner Austin Y , Dixon Graham 
Published: November 2023

Abstract
Using a nationally representative sample of Democrats and Republicans (n = 1,000), we conducted an online survey wording experiment to examine the presence of a labeling effect when a vaccine verification system is referred to as either “vaccine passports” or “vaccine verification.” Critically, we use both close-ended and open-ended responses in order to understand how the different labels influence the level of support as well as individual thoughts. While our findings show slightly higher public support when a vaccine program is labeled as “vaccine verification” as compared to “vaccine passport,” deep partisan divides still exist. Indeed, Republicans show less support for a vaccine program, regardless of the label used. We dig into these partisan differences using the open-ended thought listing exercise we provided to respondents. We discuss the benefits of supplementing open-ended responses as an enhancement to close-ended measures in experimental research.
Planktonic and biofilm states of Staphylococcus aureus isolated from bone and joint infections and the in vitro effect of orally available antibiotics
Authors: Perez-Alba Eduardo , Flores-Treviño Samantha , Villarreal-Salazar Verónica , Bocanegra-Ibarias Paola , Vilchez-Cavazos Félix , Camacho-Ortiz Adrián 
Published: November 2023

Abstract

Aims
To demonstrate the in vitro activity of orally available antibiotics against Staphylococcus aureus isolated from bone or orthopedic implant materials. The biofilm eradication of the combination of three antibiotics was also assessed.

Methods and results
Clinical isolates from orthopedic infection samples were collected, and S. aureus isolates were classified according to their biofilm production and composition. Almost all S. aureus isolates (n = 36, 97.3%) produced biofilm and the major biofilm components were polysaccharides. Antimicrobial susceptibility was determined in planktonic (minimal inhibitory concentration; MIC) and biofilm cells (minimal biofilm eradication concentration; MBEC) using the MBEC Calgary Device. Overall, the MBEC ranged higher than the MIC. When combined at borderline-susceptible concentrations, moxifloxacin–rifampin and doxycycline–rifampin were both able to eradicate biofilms in a third of the strains whereas the doxycycline–moxifloxacin combination proved ineffective at eradicating biofilm, inhibiting it only in three strains.

Conclusions
We propose rifampin in combination with moxifloxacin or doxycycline for the design of clinical trials of bone and/or orthopedic device infection without proper debridement or material retention.
Methoxetamine and its metabolites: Postmortem determination in body fluids of human cadaver
Authors: Bursová Miroslava , Hložek Tomáš , Sokol Miloš , Židková Monika , Čabala Radomír 
Published: November 2023

Abstract
We report the forensic case of a 42-year-old man, a known drug user, who died at home and whose body was only discovered 2 months later. Autopsy was performed on a corpse in the late postmortem stage where no apparent cause of death was found. A toxicological screening of biological materials (blood, urine and gastric content) using liquid chromatography with different types of mass detection (ion trap and high-resolution) revealed the presence of methoxetamine (MXE), a ketamine analog, and its metabolites. MXE and a number of its metabolites (e.g., O-desmethyl, N-desethyl, hydroxy, glucuronides and sulfates) were identified in urine. Based on the results, a method using liquid chromatography with tandem mass spectrometry was developed and validated for the determination of MXE concentration in biological materials. The following values of MXE concentration were found: blood—3.6 ng/mL, urine—70.5 ng/mL and gastric content—18.0 ng/mL. Given the absence of other drugs, medications and poisons, it can be inferred that despite relatively low blood concentrations, MXE contributed to the victim’s death. The present case demonstrates that even after 2 months, MXE and its several metabolites can be detected and determined in the human cadaver at a relatively advanced stage of decomposition.
Burn Injury-related Growth Factor Expressions and Their Potential Roles in Burn-related Neuropathies
Authors: Chaker Sara C , Saad Mariam , Mayes Taylor , Lineaweaver William C 
Published: November 2023

Abstract
In the context of burn injury, growth factors (GFs) play a significant role in mediating the complex local and systematic processes that occur. Among the many systemic complications that arise following a burn injury, peripheral neuropathy remains one of the most common. Despite the broad understanding of the effects GFs have on multiple tissues, their potential implications in both wound healing and neuropathy remain largely unexplored. Therefore, this review aims to investigate the expression patterns of GFs prominent during the burn wound healing process and explore the potential contributions these GFs have on the development of burn-related peripheral neuropathy.
Testing the heat treatment dose for Agrilus planipennis (Coleoptera: Buprestidae) prepupae using the Humble water bath
Authors: Noseworthy Meghan K , Souque Tyranna J , MacQuarrie Chris J K , John Esme P , Gray Meghan , Roberts Josie , Allen Eric A 
Published: November 2023

Abstract
The lethal heat treatment dose (time and temperature) for the prepupal life stage of Agrilus planipennis Fairmaire (Coleoptera: Buprestidae), emerald ash borer (EAB), was determined through an in vitro application using a carefully calibrated heat treatment apparatus. The lethal and sublethal effects of heat on A. planipennis prepupae were assessed through a ramped heat delivery application, simulating industrial kilns and conventional heat chamber operations, for treatments combining target temperatures of 54 °C, 55 °C, and 56 °C, and exposure durations of 0 min (i.e., kiln temperature ramp only), 15 min, or 30 min. Prepupal EAB larvae did not survive exposure to 56 °C for 15 min or longer, or to 55 °C for 30 min. Sublethal effects were observed for all other treatments. Sublethal effects included delayed development and failure to complete the pupal and adult life stages.
Pressure and rate distribution performance of a multiple-fractured well with multi-wing fracture in low-permeability gas reservoirs
Authors: Zhang Chengwei , Zhang Yunjun , Zhang Haotian , Bai Wenpeng 
Published: November 2023

Abstract
In this work, a new mathematical model of a fractured well considering multiple factors (permeability stress sensitivity, multiple well interference, and multiple fracture interference) is established to simulate wellbore pressure performance and rate distribution in tight gas reservoirs. The new fracture discrete coupling mathematical model is established. The wellbore pressure solution can be obtained by pressure drop superposition and Stehfest numerical inversion. Seven flow stages are observed according to the characteristics of the pressure derivative curve. The influence of several significant parameters, including rate ratio, fracture half-length, well spacing, and stress sensitivity are discussed. Based on the developed model, we demonstrated a field case to verify model accuracy. This work provides new supplementary knowledge to improve pressure data interpretation for multi-well groups in tight gas reservoirs.
Systematic Review of Biological, Chemical, Ergonomic, Physical, and Psychosocial Hazards Impacting Occupational Health of United States Forestry Workers
Authors: Knecht Heidi , Balanay Jo Anne G , Langley Ricky , Tutor Marcom Robin , Richards Stephanie L 
Published: November 2023

Abstract
Forestry is one of the most hazardous occupations, due in part to the biological, chemical, ergonomic, physical, and psychosocial aspects of the job. Here, we review health risks in forestry occupations, including those in professional and technical forestry, logging, and forestry support, from the standpoint of biological (e.g., insects/arachnids, plants), chemical (e.g., diesel exhaust), ergonomic (e.g., awkward postures, forceful motions), physical (temperature, noise, vibrations, radiation), and psychosocial (e.g., workplace factors that cause stress, strain, or interpersonal problems for the worker) issues. We conducted a systematic review over a 10-year period (2011–2021) to assess health hazards identified in studies conducted on these occupations and reveal knowledge gaps for future studies to address. This study focuses on occupational health rather than occupational safety. Other forestry worker occupational health and safety studies have focused on analyzing injuries and deaths directly relating to transportation and/or contact with objects such as trees or logs and equipment; however, the areas of occupational health highlighted here have been understudied. Future work should focus on these areas, with an emphasis on intervention strategies that eliminate or mitigate the deleterious health effects of occupational exposures.
Study Implications: Forestry workers are exposed to occupational health hazards in their outdoor workplace. This review analyzes published work for a 10-year period (2011–2021) with broader implications such as (1) greater understanding of gaps in the literature for key occupational health hazards facing United States forestry workers and (2) better information on the need for more in-depth studies to collect information about exposure assessments to improve worker protection. This literature review can help forestry workers, managers, and scientists mitigate exposures and protect health.
Assessing Public Attitudes toward Random versus Symbolic Terrorist Targets: Survey Experimental Evidence
Authors: Gift Thomas , Norman Julie M , Davidson Rob 
Published: November 2023

Abstract
Do citizens react more adversely to terrorism that strikes random or symbolic targets? Despite the relative neglect of this question by conflict scholars, few attributes of terrorist attacks are more scrutinized by the public. In this article, we field a pair of preregistered, national survey experiments in the United Kingdom that measure the impact of random and symbolic targeting on public demands for armed retaliation. We find that results appear to vary depending on the level of stylization with which the attack is presented. In the abstract, citizens support more retaliation for terrorism directed at random targets. Yet when more concrete details are presented, citizens become similarly defensive of national symbols. We attempt to reconcile this apparent discrepancy by drawing on insights from political psychology, which lead us to propose that changes to the stylization of stimuli may induce citizens to emphasize different cognitive and emotional responses related to random and symbolic targeting. Our results call for more study into how the presentation of terrorist attacks affects public reactions.
Tensile and compressive mechanical properties of nanocrystalline calcite with grain size effect
Authors: Luo Chaocai , Yang Xinhua , Li Jie 
Published: November 2023

Abstract
Calcite is one of the most main components of microbially induced calcium carbonate precipitation (MICP). With the in-depth research of MICP, the mechanical properties of nanocrystalline calcite attract much attention. In this paper, the deformation and failure behaviors of nanocrystalline calcite under a uniaxial tensile or compressive condition are studied by molecular dynamics simulation, and then the dominant deformation and failure mechanisms, as well as their grain size effect, are analyzed. The results show that the grain boundary densification dominates the elastic deformation, while the intragranular phase transition dominates the plastic deformation. Compared with single-crystal calcite, the elastic modulus of nanocrystalline calcite is significantly reduced and its ultimate strength is decreased by more than 50%. Nanocrystalline calcite has stronger plastic deformation ability in compression than in tension. Its tensile and compressive elastic moduli and peak stresses all increase with the average grain size. The effects of grain size on the limit stresses can be described by the inverse Hall–Petch equation. This study is helpful for tailoring the mechanical properties of MICP by the morphology of nanocrystalline calcite.
Real-World Adoption of Mental Health Support Among Adolescents: Cross-Sectional Analysis of the California Health Interview Survey
Authors: Zhao Xin , Schueller Stephen M , Kim Jeongmi , Stadnick Nicole A , Eikey Elizabeth , Schneider Margaret , Zheng Kai , Mukamel Dana B , Sorkin Dara H 
Published: November 2023

Abstract

Objective
We aim to examine: (a) the extent to which patterns of adoption of counseling services and digital mental health interventions (DMHIs) shifted in recent years (2019–2021); (b) the impact of distress on adoption of mental health support; and (c) reasons related to adolescents’ low adoption of DMHIs when experiencing distress.

Methods
Data were from three cohorts of adolescents aged 12–17 years (n = 847 in 2019; n = 1,365 in 2020; n = 1,169 in 2021) recruited as part of the California Health Interview Survey. We estimated logistic regression models to examine the likelihood of using mental health support as a function of psychological distress, sociodemographic characteristics, and cohorts. We also analyzed adolescents’ self-reported reasons for not trying DMHIs as a function of distress.

Results
The proportion of adolescents reporting elevated psychological distress (∼50%) was higher than those adopting counseling services (&lt;20%) or DMHIs (&lt;10%). A higher level of distress was associated with a greater likelihood of receiving counseling (OR = 1.15), and using DMHIs to connect with a professional (Odds ratio (OR) = 1.11) and for self-help (OR = 1.17). Among those experiencing high distress, adolescents’ top reason for not adopting an online tool was a lack of perceived need (19.2%).

Conclusion
Adolescents’ main barriers to DMHI adoption included a lack of perceived need, which may be explained by a lack of mental health literacy. Thoughtful marketing and dissemination efforts are needed to increase mental health awareness and normalize adoption of counseling services and DMHIs.
Invasive Group A Streptococcus in Infants Less Than 1-year of Age From 2012 to 2022: A Single-Center Experience
Authors: Nack Taylor , Vallejo Jesus G , Dunn James , Flores Anthony R , McNeil J Chase 
Published: November 2023

Abstract
The incidence of invasive Group A Streptococcus (iGAS) has varied throughout the COVID-19 pandemic. We reviewed iGAS infections in infants ≤1 year from 2012 to 2022. Twenty-five percent of cases occurred in the last quarter of 2022. Pneumonia (21.8%) was the most common presentation. Twenty-one patients (65.6%) were successfully transitioned to oral antibiotics.
Improving Donor Imputation Using the Prediction Power of Random Forests: a Combination of SwissCheese and missForest
Authors: Tripet Arnaud , Eustache Esther , Tillé Yves 
Published: November 2023

Abstract
Imputation procedures are frequently used to treat nonresponse. With random hot deck imputation, missing values are replaced by valid observed values from other units in the same dataset. The recently developed balanced nearest neighbor imputation method, implemented in the SwissCheese R package, generates random hot deck imputation under certain balancing constraints to decrease the variance of the total estimator, in the presence of multivariate nonresponse. The method relies on a notion of neighborhood between units, utilizing a distance measure that becomes difficult to define in high dimensions. In contrast to hot deck imputation methods, many imputation procedures obtain replacement values from prediction models fit from observed data. The missForest method, which uses random forests as prediction models, is an example of this approach. In this article, we propose a new approach that uses the two methods in a complementary manner. We refine the distance measure in the SwissCheese method using missForest predictions. Through a simulation study on empirical data from the Swiss Survey on Income and Living Conditions, we demonstrate reductions in Monte Carlo variance, bias, and mean squared error of the totals obtained by our proposed imputed estimator compared to those obtained using SwissCheese alone.
Compact stars with dark matter induced anisotropy in complexity-free background and effect of dark matter on GW echoes
Authors: Maurya S K , Singh Ksh Newton , Aziz Abdul , Ray Saibal , Mustafa Ghulam 
Published: November 2023

ABSTRACT
In this work, we consider the vanishing complexity factor scenario which has opened up a whole new way of generating solutions to the Einstein field equations for the spherically symmetric structure of celestial bodies. By using this very rare condition on the system of two metric potentials, viz. gtt and grr, we make reduce it to a uni-metric potential system satisfying all physical conditions. Along with this, we further have considered that the space–time is deformed by dark matter (DM) content in DM haloes resulting into perturbations in the gtt and grr metric potentials. This DM deformation is mathematically done by the complete geometric decoupling method where the decoupling parameter β decides the amount of DM content. In connection to the claimed post-merger object in the GW170817 event we have argued that if these compact stars were in galactic DM haloes with the assumption that the radius remains the same, the compactness factor can grow within the range 1/3 to 4/9 and therefore can generate gravitational waves (GW) echoes. Additionally, we have presented effect of β on the generation of GW echoes in accordance with the observational constraints related to the compact stars GW190814, PSR J0740+6620, PSR J1614−2230, Cen X-3, and LMC X-4.
Exploring the multiband gravitational wave background with a semi-analytic galaxy formation model
Authors: Li Zhencheng , Jiang Zhen , Fan Xi-Long , Chen Yun , Gao Liang , Guo Qi , Yu Shenghua 
Published: November 2023

ABSTRACT
An enormous number of compact binary systems, spanning from stellar to supermassive levels, emit substantial gravitational waves during their final evolutionary stages, thereby creating a stochastic gravitational wave background (SGWB). We calculate the merger rates of stellar compact binaries and massive black hole binaries using a semi-analytic galaxy formation model – Galaxy Assembly with Binary Evolution (GABE) – in a unified and self-consistent approach, followed by an estimation of the multiband SGWB contributed by those systems. We find that the amplitudes of the principal peaks of the SGWB energy density are within one order of magnitude ΩGW ∼ 10−9–10−8. This SGWB could easily be detected by the Square Kilometre Array (SKA), as well as by the planned interferometric detectors, such as the Einstein Telescope and the Laser Interferometer Space Antenna (LISA). The energy density of this background varies as ΩGW ∝ f2/3 in the SKA band. The shape of the SGWB spectrum in the frequency range ∼[10−4,1] Hz could allow the LISA to distinguish the black hole seed models. The amplitude of the SGWB from merging stellar binary black holes at ∼100 Hz is approximately 10 and 100 times greater than those from merging binary neutron stars and neutron-star–black-hole mergers, respectively. Note that, since the cosmic star formation rate density predicted by GABE is somewhat lower than the observational results by ∼0.2 dex at z &lt; ∼2, the amplitude of the SGWB in the frequency range ∼[1, 104] Hz may be underestimated by a similar factor at most.
Mergers of black hole binaries driven by misaligned circumbinary discs
Authors: Martin Rebecca G , Lepp Stephen , Zhang Bing , Nixon C J , Childs Anna C 
Published: November 2023

ABSTRACT
With hydrodynamical simulations we examine the evolution of a highly misaligned circumbinary disc around a black hole binary including the effects of general relativity. We show that a disc mass of just a few per cent of the binary mass can significantly increase the binary eccentricity through von-Zeipel–Kozai–Lidov (ZKL) like oscillations provided that the disc lifetime is longer than the ZKL oscillation time-scale. The disc begins as a relatively narrow ring of material far from the binary and spreads radially. When the binary becomes highly eccentric, disc breaking forms an inner disc ring that quickly aligns to polar. The polar ring drives fast retrograde apsidal precession of the binary that weakens the ZKL effect. This allows the binary eccentricity to remain at a high level and may significantly shorten the black hole merger time. The mechanism requires the initial disc inclination relative to the binary to be closer to retrograde than to prograde.