bluuebunny/crossref_metadata_2025_split huggingface dataset:
The antifungal substance from Bacillus velezensis B‐3 improved the malt quality against premature yeast flocculation induced by Fusarium graminearum infection
Authors: Xie Ying , Zhang Ming , Wu Dianhui , Cai Guolin , Lu Jian 
Published: November 2023

AbstractMalt produced from barley contaminated with Fusarium graminearum can cause premature yeast flocculation (PYF) in beer fermentation, which ultimately affects the production efficiency and flavor quality of beer. In this study, a strain of Bacillus velezensis B‐3 that was isolated from soil displayed strong antifungal activity against F. graminearum. The antifungal substances were extracted and separated by ammonium sulfate fractional precipitation and semipreparative high‐performance liquid chromatography to obtain fraction VI with the strongest antifungal activity. Ultra‐performance liquid chromatography‐quadrupole‐time‐of‐flight‐mass spectrometry was used to identify that the fraction contained lipopeptides such as iturin A, surfactant B, and surfactant C. The minimum inhibitory concentration of the fraction was 0.2 mg/mL, and confocal laser scanning microscopy showed that the morphology of F. graminearum hyphae was obviously abnormal, with most of them were dead. Antifungal fraction VI could inhibit the growth of F. graminearum and avoid the production of PYF factor during malting but did not affect other qualities of malt. Therefore, the development of antimicrobial agents against Fusarium provides an effective potential strategy to control the production of PYF factors for malt‐manufacturing enterprises.Practical ApplicationAntifungal fraction VI could inhibit the growth of F. graminearum and the formation of DON during malting but did not affect other qualities of malt. The levels of soluble nitrogen, free amino nitrogen, and color experienced a substantial reduction compared to the malt infected by F. graminearum. The PYF phenomenon was significantly improved, the number of suspended yeast cells and the degree of fermentation were increased, and the level of residual extract in the wort was low, close to that of control malt.
Optimization of ultrasound‐assisted extraction of sorghum phenolics and effect on the stability of 3‐deoxyanthocyanins
Authors: Santos Paula Cristina Silva , Teixeira Bárbara Avancini , Queiroz Valéria Aparecida Vieira , Vidigal Márcia Cristina Teixeira Ribeiro , Stringheta Paulo César , de Barros Frederico Augusto Ribeiro 
Published: November 2023

AbstractSorghum 3‐deoxyanthocyanins (3‐DXAs) have greater stability when compared to other anthocyanins. However, the efficiency in extracting these phenolic compounds from cereals, using conventional methods, is low, because most of them are bound to the cell wall. Thus, the aim of this study was to optimize the ultrasound‐assisted extraction (UAE) of anthocyanins and total phenolics from sorghum flour, and evaluate the stability of the 3‐DXAs. Two frequencies (25 and 45 kHz) were applied in a Central Composite Rotational design to investigate the effect of the variables time (5–75 min) and temperature (30–65°C) using the UAE, with amplitude of the ultrasonic power set at 400 W. In addition, the stability of the 3‐DXAs present in the extracts was evaluated. It was possible to successfully optimize the extraction of total anthocyanins (both frequencies) and phenolics (at 45 kHz), and then to obtain equations, to predict their concentrations, with high R2. The efficiency of UAE was observed, increasing the yield of total anthocyanins, phenolics, and antioxidant capacity at the frequencies of 25 and 45 kHz by 30% and 27%, 10% and 5%, and 30% and 15%, respectively. The apigeninidin was the major 3‐DXA found in the extracts, and the luteolinidin was the most stable over storage time. Overall, there was no difference in the 3‐DXAs stability obtained by the UAE compared to the conventional method. Thus, ultrasound is an alternative to obtaining sorghum extracts rich in 3‐DXAs and other phenolic compounds.Practical ApplicationThe health benefits of sorghum 3‐deoxyanthocyanins coupled with the growing interest of the food industry in producing healthier food products have motivated this study, because it is important to find ways to optimize 3‐deoxyanthocyanins extraction. We have demonstrated that ultrasound‐assisted extraction was efficient in extracting high amounts of 3‐deoxyanthocyanins and other phenolics from sorghum flour. Moreover, some 3‐deoxyanthocyanins have shown to be more stable than others after extraction. Thus, the ultrasound has great potential to produce sorghum phenolic extracts rich in 3‐deoxyanthocyanins, which can be used as natural colorants and functional ingredients in foods.
Secular trends of morbidity and mortality of thyroid cancer in five Asian countries from 1990 to 2019 and their predictions to 2035
Authors: Tang Shi‐Di , Zi Hao , Tao Hua , Huang Qiao , Guo Xing‐Pei , Deng Tong , Li Fei 
Published: November 2023

AbstractBackgroundThe rising burden of thyroid cancer (TC) is a public health problem in Asia. Predicting the future burden of TC in Asian countries is essential for disease prevention.MethodsData were obtained from the Global Burden of Disease 2019 for five Asian countries. We applied Bayesian age‐period‐cohort models to predict morbidity and mortality to 2035 and calculated age‐standardized incidence rate (ASIR) and age‐standardized mortality rate (ASMR). Furthermore, the estimated annual percentage change was calculated to evaluate the variation of ASIR and ASMR.ResultsBy 2035, predictions suggest that cases of TC will reach 75.56 × 103 in China, 70.22 × 103 in India, 15.78 × 103 in the Republic of Korea, 9.01 × 103 in Japan and 5.55 × 103 in Thailand, respectively. Except Japan, a significant upward trend of ASIR of TC will be observed in five Asian countries. The deaths from TC will increase in five countries and India will become the highest reaching 14.07 × 103. The ASMR will rise to 0.83/100 000 in India and 1.06/100 000 in the Republic of Korea, while it will drop to 0.35/100 000 in China, 0.43/100 000 in Japan and 0.50/100 000 in Thailand. In further predictions projected by sex, the growth rate of ASIR is reported higher in males than in females among most countries. ASMR of male will exceed that of females in China and Thailand by 2035.ConclusionThe disease burden caused by TC will further increase in five Asian countries, especially for men. It is necessary to develop more rational and timely disease prevention and manage strategies facing this disease trend.
The buzzOmeter system: In situ audio recordings of pollinators in flight
Authors: Volponi Paolo , Dapporto Leonardo , Skowron Volponi Marta 
Published: November 2023

Abstract

The role of sounds produced by free‐flying insects is challenging to research due to technical difficulties in obtaining audio recordings suitable for playback experiments. Experimental studies using flight sounds are needed to understand if buzzes carry information and by whom it is perceived.

We developed the ‘buzzOmeter system’ for recording untethered, flying insects in their habitat, followed by file processing that allows precise measurements of acoustic parameters, including those dependent on the distance of the sound source from the microphone, that is signal magnitude measurements. The system consists of commercially available elements and open source software.

We provide a practical guide for the assembly and use of two alternative setups of the buzzOmeter system, followed by a video tutorial on file processing and an R script for the assignment of audio recordings to the corresponding species based on mixture discriminant analysis. Recordings of nine insect species (bees, wasps and lepidopterans) obtained with the use of our system in various habitats demonstrate its feasibility for field studies.

Diverse species interactions are based on sound, and our new tool can aid researchers studying acoustical signalling in predator–prey, pollinator‐plant and mimic‐model complexes, among others.
How do big customers influence bank loans in China? The role of state ownership and political connections
Authors: Deng Li , Huang Peng , Lu Yue , Weng Hongjie 
Published: November 2023

AbstractFirms with big customers are associated with not only high operational efficiency but also high operational risks. We study the effect of big customers on various aspects of bank loan contracts using a manually collected contract‐level dataset from China over the period of 2001–2016. We find that, big customers help firms obtain lower borrowing interest rates, longer loan duration, and larger loan amounts, though this is accompanied by more restrictive borrowing conditions. We further find that state ownership and political connections are important considerations when banks make loan decisions to firms with big customers. Overall, our results show how benefits and costs of big customers are evaluated by banks and priced into bank loan contract terms.
The prevalence and linkage disequilibrium of 21 genetic variations related to thrombophilia, folate cycle, and hypertension in reproductive age women of Rostov region (Russia)
Authors: Bordaeva Oksana Yurievna , Derevyanchuk Ekaterina Grigorievna , Alset Dema , Amelina Maria Aleksandrovna , Shkurat Tatiana Pavlovna 
Published: November 2023

AbstractSeveral maternal genetic variations are known to play an important role during pregnancy since they can affect mother health and/or fetal growth. The frequency of these variants is variable among different populations. This study aimed to investigate thrombophilia, folate metabolism and hypertension genetic variants in reproductive age women of Rostov region (Russia) and then assess their linkage disequilibrium (LD) and heterogeneity among populations. A total of 3108 reproductive age women were included (33.75 ± 5.13 years). Twenty‐one genetic variants were detected with RT‐PCR. LD was tested according to (D′) coefficient and p value. The highest frequency of mutant allele in studied population was as follows: PAI‐1 rs1799768, MTRR rs1801394, AGT rs699, and AGTR2 rs1403543. We showed a high possibility of coinheritance of MTHFR rs1801133 with rs1801131 and AGT rs699 with rs4762 (D′=0.992 and 0.999, respectively). In addition, comparative analysis showed F7 rs6046, FGB rs1800790, MTR rs1805087, and AGT rs699 significantly more frequent among Rostov females by 1.3–1.5 times than European. MTHFR rs1801133, ADD1 rs4961, AGTR2 rs1403543, NOS3 rs2070744, and rs1799983 were with higher frequencies in Europeans than those in the studied group. Our data could be used as a reference for further associative studies of targeted genetic variations in different pregnancy complications specifically in this population.
Bending Possession: How Detroiters Care for Land by Remediating Settler Property
Authors: Caverly Nicholas L. 
Published: November 2023

AbstractThis article examines how people reconfigure the social, legal, and material claims that settler property relations make to place. It does so through ethnographic and historical attention to small‐scale gardens in Detroit, Michigan. When present‐day Detroiters transform grassy lots into gardens and places of shared enjoyment, they frequently encounter how antiblack environmental conditions are grafted with property claims created through settler‐colonial dispossession of Indigenous lands. Gardeners document encounters with the simultaneity of settler plotlines and contaminated soils as part of efforts to secure gardens from encroachment by real estate developers. As gardeners leverage legal conventions of settler property regimes like adverse possession manoeuvres, they also refuse the sociomaterial status quo of colonial land relations. In conversation with Detroiters and their gardens, this article offers bending possession as a handle for methods people develop that begin to provisionally redirect the violence of private property that sustains colonial racial capitalism.
Imager—A mobile health mental imagery‐based ecological momentary intervention targeting reward sensitivity: A randomized controlled trial
Authors: Marciniak Marta Anna , Shanahan Lilly , Myin‐Germeys Inez , Veer Ilya Milos , Yuen Kenneth S. L. , Binder Harald , Walter Henrik , Hermans Erno J. , Kalisch Raffael , Kleim Birgit 
Published: November 2023

AbstractRobust reward sensitivity may help preserve mental well‐being in the face of adversity and has been proposed as a key stress resilience factor. Here, we present a mobile health application, “Imager,” which targets reward sensitivity by training individuals to create mental images of future rewarding experiences. We conducted a two‐arm randomized controlled trial with 95 participants screened for reward sensitivity. Participants in the intervention group received an ecological momentary intervention—Imager, which encouraged participants to create mental images of rewarding events for 1 week. The control group participants received only ecological momentary assessment, without the instruction to generate mental images. Adherence to Imager was high; participants in the intervention group engaged in 88% of the planned activities. In the follow‐up assessment, the intervention group reported less mental health symptoms, mainly in depression (β = −0.34, df = 93, p = .004) and less perceived stress (β = −0.18, df = 93, p = .035), than control group participants and compared with the baseline assessment. Our results show the positive effects of Imager on mental health symptoms. The encouraging effects of the app on mental health outcomes may lead to greater use of ecological momentary interventions in the clinical preventive practice of affective disorders.
Percutaneous nephrolithotomy vs retrograde intrarenal surgery for renal stones: a Cochrane Review
Authors: Soderberg Leah , Ergun Onuralp , Ding Maylynn , Parker Robin , Borofsky Michael , Pais Vernon , Dahm Philipp 
Published: November 2023

ObjectivesTo assess the effects of percutaneous nephrolithotomy (PCNL) vs retrograde intrarenal surgery (RIRS) for the treatment of renal stones in adults.MethodsWe performed a comprehensive search of the Cochrane Library, MEDLINE, Embase, three other databases, trials registries, other sources of the grey literature, and conference proceedings up to 23 March 2023. We applied no restrictions on publication language or status. Screening, data extraction, risk‐of‐bias assessment, and certainty of evidence (CoE) rating using the Grading of Recommendations Assessment, Development and Evaluations (GRADE) approach were done in duplicate by two independent reviewers. This co‐publication focuses on the primary outcomes of this review only.ResultsWe included 42 trials that met the inclusion criteria. Stone‐free rate (SFR): PCNL may improve SFRs (risk ratio [RR] 1.13, 95% confidence interval [CI] 1.08–1.18; I2 = 71%; 39 studies, 4088 participants; low CoE). Major complications: PCNL probably has little to no effect on major complications (RR 0.86, 95% CI 0.59–1.25; I2 = 15%; 34 studies, 3649; participants; moderate CoE) compared to RIRS. Need for secondary interventions: PCNL may reduce the need for secondary interventions (RR 0.31, 95% CI 0.17–0.55; I2 = 61%; 21 studies, 2005 participants; low CoE) compared to RIRS.ConclusionDespite shortcomings in most studies that lowered our certainty in the estimates of effect to mostly very low or low, we found that PCNL may improve SFRs and reduce the need for secondary interventions while not impacting major complications. Ureteric stricture rates may be similar compared to RIRS. We expect the findings of this review to be helpful for shared decision‐making about management choices for individuals with renal stones.
One ant's trash is another ant's treasure: Army ant middens provide resources for diverse ant assemblages
Authors: Robles López Karen Y. , Sosa‐Calvo Jeffrey , Calixto Juliana M. , Zoppas de Albuquerque Emilia , Baudier Kaitlin M. 
Published: November 2023

AbstractThe army ant Eciton burchellii boasts more animal associates than any other animal species yet described, but the relationship between army ants and other ant species has only been studied in the context of predation. The waste deposits (middens) of army ant colonies are nitrogen‐rich, a potentially high‐value nutrient source for leaflitter arthropods. We explored this bottom‐up role of army ant middens in the context of tropical ant communities. Our three main questions were the followings: (1) Which ant species forage on army‐ant middens? (2) How does the bi‐phasic life cycle of army ant colonies (affecting midden size, persistence, and abundance) affect which and how many ant species a midden boasts? (3) How do the ants that forage on army ant middens differ across elevations? Across 39 bivouacs, we found 36 species of ants foraging on army ant middens. These included highly predatory ants, nitrogen‐limited arboreal ants, and fungus‐farming ants. Per‐midden richness was significantly lower for the usually smaller middens deposited during the nomadic phase and was higher for the typically larger middens deposited during the statary phase. Per‐midden richness was not significantly different across elevations, but there was far greater species turnover across elevations than across phases within the same elevational site. Our results suggest that army ant middens are an important resource for a wide variety of tropical ants, informing a better understanding of the complex network of associations revolving around this keystone species.Abstract in Spanish is available with online material
CircBRD7 attenuates tumor growth and metastasis in nasopharyngeal carcinoma via epigenetic activation of its host gene
Authors: Wei Jianxia , Li Mengna , Chen Shipeng , Xue Changning , Zheng Lemei , Duan Yumei , Deng Hongyu , Fan Songqing , Xiong Wei , Zhou Ming 
Published: November 2023

AbstractBRD7 was identified as a tumor suppressor in nasopharyngeal carcinoma (NPC). Circular RNAs (CircRNAs) are involved in the occurrence and development of NPC as oncogenes or tumor suppressors. However, the function and mechanism of the circular RNA forms derived from BRD7 in NPC are not well understood. In this study, we first identified that circBRD7 was a novel circRNA derived from BRD7 that inhibited cell proliferation, migration, invasion of NPC cells, as well as the xenograft tumor growth and metastasis in vivo. Mechanistically, circBRD7 promoted the transcriptional activation and expression of BRD7 by enhancing the enrichment of histone 3 lysine 27 acetylation (H3K27ac) in the promoter region of its host gene BRD7, and BRD7 promoted the formation of circBRD7. Therefore, circBRD7 formed a positive feedback loop with BRD7 to inhibit NPC development and progression. Moreover, restoration of BRD7 expression rescued the inhibitory effect of circBRD7 on the malignant progression of NPC. In addition, circBRD7 demonstrated low expression in NPC tissues, which was positively correlated with BRD7 expression and negatively correlated with the clinical stage of NPC patients. Taken together, circBRD7 attenuates the tumor growth and metastasis of NPC by forming a positive feedback loop with its host gene BRD7, and targeting the circBRD7/BRD7 axis is a promising strategy for the clinical diagnosis and treatment of NPC.
Family math engagement with young Latine children in the United States
Authors: Swirbul Mackenzie , Melzi Gigliana 
Published: November 2023

AbstractYoung children's early math experiences are culturally situated, occurring in the context of everyday family interactions and routines. Yet, we know little about the math experiences in culturally and linguistically minoritized families, including those from Latine communities. In this article, we provide the first review of research on family math in the homes of young Latine children in the United States. We identify shared patterns and inconsistencies across studies on family math cognitions and math practices, and their relations with children's outcomes. We argue for the need to use a sociocultural lens to examine and understand family math, and offer recommendations that center families' experiences to generate foundational knowledge, capture within‐group variation, and use more flexible and culturally relevant measures.
Staging the New City: Urban spectacles and the ecological origins of Nayib Bukele's authoritarian populism
Authors: Gutiérrez Julio 
Published: November 2023

AbstractThis paper analyzes the connections between real estate speculation and authoritarian populism in El Salvador. Focusing on president Nayib Bukele's term as mayor of Nuevo Cuscatlán (2012–2015), I examine the role speculative urbanism played in the crafting of his profile as a promising politician in the early years of his career. I trace how Bukele instrumentalized the ecosystem of Nuevo Cuscatlán's coffee forest as a means to fund a personalistic populist strategy whose main project called for the construction of a “New City.” This project involved the lifting of barriers to real estate investment to raise funds for social programs and municipal infrastructure. Its flipside was an aggressive process of deforestation and displacement of rural populations. Drawing on urban political ecology and critical agrarian studies, I argue that Bukele's New City project constituted a type ofurban spectacle. This urban spectacle was rooted in two socio‐ecological dynamics: (1) The use of land as a revenue‐raising token of exchange; and (2) The fetishization of urban water infrastructure in the context of water scarcity. The paper concludes with various considerations about the destructive force of the link between authoritarian populism and urban extractivism in rural environments.
Weight change in patients with new‐onset type 2 diabetes mellitus and its association with remission: Comprehensive real‐world data
Authors: Kim Jinyoung , Kim Bongseong , Kim Mee Kyoung , Baek Ki‐Hyun , Song Ki‐Ho , Han Kyungdo , Kwon Hyuk‐Sang 
Published: November 2023

AbstractAimsWe aimed to investigate weight change in patients with new‐onset type 2 diabetes mellitus and the association of weight loss on diabetes remission in Korean adults.Materials and MethodsWe used the health examination database of the Korean National Health Insurance Service. Patients diagnosed with type 2 diabetes mellitus from 2009 to 2012 were enrolled and followed to 2017. The baseline body weight was measured at the health examination closest to the time the patient was enrolled, and the change was calculated by examining the weight measured at the subsequent examination within 2 years. Remission was defined as fasting blood glucose less than 126 mg/dl at two or more consecutive health examinations after stopping medication.ResultsIn total, 114, 874 patients with new‐onset type 2 diabetes mellitus were analysed. Of these, 23 156 (20.2%) lost more than 5% of their body weight, and 2429 (2.1%) achieved remission. The adjusted odds ratio for remission in the weight loss group was 2.56 (95% confidence interval 2.35‐2.79) compared with the group with stable body weight. Sensitivity analysis according to the degree of weight change showed that the greater weight loss, the higher the likelihood of remission. In the subgroup analysis, the effects of weight loss on remission were significantly greater in subgroups of age <65 years, male sex and body mass index >25.ConclusionWeight loss within the first 2 years of treating type 2 diabetes mellitus was associated with diabetes remission. Physicians should pay more attention to weight management in new‐onset type 2 diabetes mellitus, particularly for young and obese individuals.