bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of the immunoassay method with the commercial and in-house LC-MS/MS methods for substance abuse in urine
Authors: Avcioglu Gamze , Yilmaz Gulsen , Yalcin Sahiner Safak , Kozaci L. Didem , Bal Ceylan , Yilmaz Fatma Meric 
Published: October 2023

Abstract

Objectives
The aim of this study was to compare the analytical performance of the KIMS (kinetic interaction of microparticles in solution) immunochemical method with a validated in-house and a commercial LC-MS/MS method.

Methods
The urine samples of the 100 subjects were included in the present study. The urine samples were analysed with Roche DAT immunochemical method based on KIMS method. In-house LC-MS/MS method was validated for 58 parameters according to the CLSI C62-A recommendations with the following parameters: matrix effect, lower limit of quantification (LLOQ), linearity, intra-day and inter-day precision and accuracy. Eureka Lab Division Drugs of Abuse kit was used as the commercial LC-MS/MS method.

Results
The immunochemical method had a satisfactory performance with specificity, sensitivity and accuracy values above 80 % and met the DRUID recommendation except benzodiazepines. The sensitivity and specificity of the immunochemical method were between 97–100 % and 84–100 %, respectively (except for benzodiazepines). The bias obtained for THC-COOH, morphine and codeine parameters were −17.5, 24.6 and 43.6 between two LC-MS/MS methods. The commercial method had a tendency to have a negative bias except for cannabinoids.

Conclusions
The analytical performance of the KIMS-based urine immunochemical method was found to be satisfactory for the intended use, except for benzodiazepines. The validated urine in-house LC-MS/MS method was found to be a good alternative for confirmation of substance abuse.
Mensch-Roboter-Kollaboration
Authors: Bunk Justus , Schell Klemens 
Published: October 2023

Abstract
Die Mensch-Roboter-Kollaboration (MRK) bietet eine Reihe von Optimierungsmöglichkeiten entlang der Produktionskette. Die Einführung von MRK gilt als vielversprechender Ansatz für die Steigerung der Wettbewerbsfähigkeit. Produzierende Unternehmen sind jedoch mit der Implementierungsplanung der kollaborativen Robotik häufig überfordert. Die Ergebnisse dieser Arbeit bieten ein methodengestütztes Prozessmodell für die Planung der Implementierung von kollaborativen Robotern in Produktionssystemen.
Time series aggregation, disaggregation and long memory
Authors: Celov Dmitrij , Leipus Remigijus 
Published: October 2023

Large-scale aggregation and its inverse, disaggregation, problems are important in many fields of studies like macroeconomics, astronomy, hydrology and sociology. It was shown in Granger (1980) that a certain aggregation of random coefficient AR(1) models can lead to long memory output. Dacunha-Castelle and Oppenheim (2001) explored the topic further, answering when and if a predefined long memory process could be obtained as the result of aggregation of a specific class of individual processes. In this paper, the disaggregation scheme of Leipus et al. (2006) is briefly discussed. Then disaggregation into AR(1) is analyzed further, resulting in a theorem that helps, under corresponding assumptions, to construct a mixture density for a given aggregated by AR(1) scheme process. Finally the theorem is illustrated by FARUMA mixture densityÆs example.
Neurodevelopmental Disorders and the Impact of Racism
Authors: Spinks-Franklin Adiaha , Mittal Shruti , Pereira-Smith Silvia , Beers Nathaniel 
Published: October 2023

The impact of racism has led to significant disparities in the diagnosis and management of neurodevelopmental disorders (NDDs) in Black, Indigenous, and People of Color (BIPOC) youth. Many NDD diagnoses, such as attention-deficit/hyperactivity disorder, learning disorders, and autism spectrum disorder, are overdiagnosed, misdiagnosed, or under-identified in BIPOC youth compared with other medical conditions (eg, asthma, diabetes). These disparities influence the types and quality of services received, leading to long-term adverse effects.
Keywords: neurodevelopmental disorders, overdiagnosis, under-identification
The Impact of Racism On Education
Authors: Dooley Danielle G. , de la Torre Desiree M. , Kinlow Tonya Vidal , Dixon Gabrina L. 
Published: October 2023

High-quality education is a critical factor for success in children and adolescents. Because of ongoing systemic racism, youth in the United States experience unequal educational opportunities depending on the schools they attend, the neighborhoods they live in, their skin color, and their families’ financial resources. Pediatric health teams and institutions can address the effects of racism in the educational system by becoming school friendly. A School-Friendly Health System is a health system actively working to ensure all children and adolescents achieve optimal health and reach their full academic potential.
Keywords: education, racism, School-Friendly Health System
Talking with White Children and Adolescents About Racism
Authors: Hagerman Margaret A. , Underhill Megan R. 
Published: October 2023

White children and adolescents form ideas about race based on their everyday experiences, interactions with others, and observations of patterns in their social environments. Although white children certainly have opinions about race and racism, many white parents and caregivers do not speak with their children about race. This chapter provides insights from current social science research about how white children learn about race and discusses best practices for communicating with white children about race in ways that promote color-conscious thought and action.
Keywords: whiteness, racism, children
Racial Trauma and Trauma-Informed Practice
Authors: Broussard Camille , Bodrick Nia Imani 
Published: October 2023

Since the seminal 1998 study linking adverse childhood experiences (ACEs) and lifelong health, ACEs have included racism. Racial or race-based traumatic stress includes overt, covert, violent, threatening, interpersonal, community-level, onetime, periodic, or daily experiences. This chapter provides examples of historical and contemporary racial trauma in the United States to ground an understanding of the need to provide culturally and racially responsive care, illustrates how to recognize trauma symptoms associated with race-based stress, and concludes with practice recommendations.
Keywords: trauma-informed practice, racial trauma, resiliency
Positive Youth Development As an Anti-Racist Strategy
Authors: Brooks Merrian J. , Brissett Daniela , Ginsburg Kenneth R. 
Published: October 2023

Adolescence, including preadolescence, is a time of profound opportunity when youth (aged 10–18 years) must have positive experiences that will shape them into contributing young adults. Yet too many people associate adolescence with problems or risk-taking behaviors. Positive youth development provides pediatric health professionals with guiding principles to create an environment where all youth can maximize adolescence to develop to their full potential. It supports all youth to develop into thriving natural explorers, a task as meaningful as when an infant learns to move or a toddler learns to communicate.
Keywords: positive youth development, resilience, strength-based programming
Achieving Equity for Opportunity Youth
Authors: Mmari Kristin , Jones Vanya 
Published: October 2023

The term opportunity youth references young people between 16 and 24 years who are neither enrolled in school nor participating in the labor force. They are among the most challenging youth to serve for pediatric health professionals, as they live and operate outside the boundaries of the usual social structures meant to protect them. This chapter explores how to meet the needs of opportunity youth, focusing on equity concerns that often disadvantage Black, Indigenous, and People of Color; institutional systems that contribute to youth becoming disconnected; and opportunities for the health care system to engage with opportunity youth.
Keywords: opportunity youth, equity, health care sector
Child Health Advocacy and Anti-Racism
Authors: Raphael Jean L. , Beers Lee Savio 
Published: October 2023

Increasing recognition of racism as a public health crisis has brought a new understanding of the historical context of marginalized communities and the policies (eg, redlining, gentrification, mass incarceration) implemented that have led to racial injustice. As pediatric health professionals embrace the necessary work of dismantling racism in medical education, clinical care, and research, they must adopt new principles and strategies in child health advocacy. This chapter provides an overview of child health advocacy, discusses advocacy as a professional standard, and outlines how to engage in advocacy centered on anti-racism.
Keywords: pediatrics, advocacy, anti-racism
The Model Minority Myth
Authors: Wong Y. Joel , Kang Jonathan 
Published: October 2023

The model minority myth (MMM) is a cluster of oppressive ideologies and stereotypes that frame certain racially minoritized groups in the United States, especially Asian Americans, as more successful and hardworking than other minoritized groups. This chapter examines the dimensions and consequences of the MMM, critiques its validity, and elucidates its implications in pediatric health care. We primarily focus on Asian Americans while acknowledging that the model minority myth, as a term, has also been applied to other minoritized groups.
Keywords: model minority, Asian Americans, Black immigrants
Chemical and mechanical analysis of VAPro-aged asphalt binders from different crude oil sources
Authors: Maschauer Daniel , Steiner Daniel , Mirwald Johannes , Hofko Bernhard 
Published: October 2023

AbstractAsphalt binders change their properties over time under natural and anthropogenic influences since they are of organic origin. This leads to a deterioration of the mechanical behavior and, thus to higher stiffness and brittleness of the binder. This phenomenon is commonly known as “aging.” As a consequence, these changes have a negative impact on the low temperature and fatigue behavior of asphalt mix layers. The standardized RTFOT for STA and PAV for LTA are used to simulate aging in the laboratory on the bitumen scale. On the asphalt mix scale, various methods have been developed for either loose material or compacted specimens. This paper presents a recently developed conditioning method called the “Viennese Aging Procedure” (VAPro) for long-term aging of compacted HMA specimens at close-to-field conditions (T = 60°C and p ≤ 1 bar). Air enriched with traces of highly oxidizing gases (ozone and nitrogen oxides) is passed through the specimens to enhance the oxidation reaction. The chemical reactions triggered by VAPro are expected to be similar to field aging. The applicability of the method is demonstrated. Mixtures containing four binders of the same grade were aged. Significant differences in aging behavior can be observed. The VAPro-aging is about 1.2 to 2.6 times stronger than that of PAV in terms of stiffness increase on the binder level. The mechanical analysis is extended with FTIR measurements. It is shown that this method is of great use in evaluating aging behavior and detecting poorly performing binders.
Expert Judgment in the 2022 Aotearoa New Zealand National Seismic Hazard Model
Authors: Christophersen Annemarie , Gerstenberger Matthew C. 
Published: October 2023

Abstract
The 2022 revision of the New Zealand National Seismic Hazard Model—Te Tauira Matapae Pūmate Rū i Aotearoa (NZ NSHM 2022) is, like other regional and national seismic hazard models, a collection of many component models that are combined via logic trees to calculate various parameters of seismic hazard. Developing, selecting, and combining component models for the NZ NSHM 2022 requires expert judgment. Informal and unstructured use of expert judgment can lead to biases. Drawing on a broad body of literature on potential biases in expert judgment and how to mitigate them, we used three approaches to incorporate expert judgment with the aim to minimize biases and understand uncertainty in seismic hazard results. The first approach applied two closely aligned group structures—the Science Team Working Groups and the Technical Advisory Group (TAG). The groups between them defined the project and made the scientific decisions necessary to produce the final model. Second, the TAG provided the function of a participatory review panel, in which the reviewers of the NSHM were actively engaged throughout the project. The third approach was performance-based weighting of expert assessments, which was applied to the weighting of the logic trees. It involved asking experts so-called calibration questions with known answers, which were relevant to the questions of interest, that is, the logic-tree weights. Each expert provided their best estimates with uncertainty, from which calibration and information scores were calculated. The scores were used to weight the experts’ assessments. The combined approach to incorporating expert judgment was intended to provide a robust and well-reviewed application of seismic hazard analysis for Aotearoa, New Zealand. Robust expert judgment processes are critical to any large science project, and our approach may provide learnings and insights for others.
Erdheim-Chester Disease Presenting as Bilateral Facial Masses
Authors: Qureshi Asim , Bakathir Abdulaziz , Qureshi Fizza , Beg Amanullah , Shalaby Asem 
Published: October 2023

Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis with unknown etiology. It is recently recognized to be neoplastic with genetic mutations affecting the mitogen-activating protein kinase (MAPK) pathway. We here present a case of a 49-year-old female who initially presented in 2012 with bilateral facial masses to a tertiary care center. These were removed but later recurred over a period of ten years. She then presented with xanthelasmas, bone lesions, secondary infertility due to hypothalamic hypogonadism, diabetes insipidus, and Hashimoto’s hypothyroidism. The facial masses were biopsied, and they showed classic morphological features in the form of diffuse infiltration by foamy histiocytes, with scattered Touton type of giant cells, patchy lymphocytic infiltrates, and dense fibrosis. The presented ECD case is particularly interesting due to the recurrent bilateral facial masses. To the best of our knowledge, this is the first documented case in Oman. The patient is stable and is being followed up in the clinic.
Keywords: Erdheim-Chester disease, Langerhans cell histiocytosis.
Special Issue on Bio-MEMS
Authors: Fujisawa Shoichiro , Sato Katsuya , Minami Kazuyuki , Nagayama Kazuaki , Sudo Ryo , Miyoshi Hiromi , Nakashima Yuta , Okeyo Kennedy Omondi , Nakahara Tasuku 
Published: October 2023

A Micro Electro-Mechanical System (MEMS) is a micro-sized mechatronic device based on semiconductor integrated-circuit manufacturing technology. MEMS technology is inherently a very powerful tool for researchers to manipulate and measure the microscopic biological components of biological tissues since their basic constituent units, cells and intracellular microstructures, are also micron or even submicron in size.
MEMS technology applied to medicine and life sciences is called Bio-MEMS. Many Bio-MEMS devices and technologies have been developed in recent years, including microfluidic devices for cell culture, manipulation, and measurement, as well as lab-on-a-chip devices for chemical reactions and analyses on MEMS devices.
This special issue consists of 13 papers: 1 review article, 1 letter, and 11 research papers. These papers include studies on mechanical stress on cells using MEMS devices, the control of cell functions through microfabrication techniques, cell measurement and in vivo microenvironment simulation using microfluidic devices, and basic research on wearable devices and self-assembling microstructures using MEMS technologies. The editorial committee members are confident that this special issue will make a significant contribution to the further development of Bio-MEMS.
We sincerely appreciate the excellent contributions of the authors and the time and effort of the reviewers. We would also like to thank the editorial board of the Journal of Robotics and Mechatronics for their support of this special issue.
Nutrition in Surgery: An Orthopaedic Perspective
Authors: Zink Thomas M. , Kent Suzanne E. , Choudhary Arjun N. , Kavolus Joseph J. 
Published: October 2023

➤ Malnutrition is common among subsets of patients undergoing orthopaedic surgery and is associated with an increased risk of postoperative complications.➤ Serum proteins, in particular, albumin, may be used in the evaluation of nutritional status.➤ Anthropometric measurements and surveys also play a role in the evaluation of nutritional status.➤ Increased energy and nutrient requirements due to surgical procedures necessitate increased caloric and protein intake in the perioperative period, which may be achieved through diet or supplementation.➤ Evidence supports the use of protein-calorie, amino acid, and immunonutrition supplements. Vitamin D supplementation is an area of further consideration.➤ Diet restriction, activity alterations, pharmacotherapy, and bariatric surgery are all safe, effective approaches to weight loss, although the optimal timing and magnitude of preoperative weight loss require further investigation.
Disseminated Erysipelothrix rhusiopathiae with Secondary Prosthetic Hip Joint Infection
Authors: McCall Matthew , Arnold Brendan , Ussher James , Sandiford N. Amir 
Published: October 2023

Case:
This article reports a case of a 72-year-old man with bilateral total hip joint replacements who suffered cuts to his hands while butchering a wild boar. He presented to the emergency department with fevers and unilateral hip pain. Erysipelothrix rhusiopathiae (E. rhusiopathiae) was isolated on hip aspirate and blood cultures. E. rhusiopathiae is a well-recognized zoonotic infection in humans, particularly in at-risk hosts, most commonly infecting swine. Infection is spread by ingestion or through skin abrasion.

Conclusion:
This illustrates an example of successful operative and perioperative management of prosthetic joint infection secondary to E. rhusiopathiae, particularly microbiological identification, within a multispecialty team of physicians and surgeons.
Ankle Skin Defects with Vascular Ehlers-Danlos Syndromes Treated by Posterior Tibial Artery Perforator Flap
Authors: Hasegawa Hideo , Kawamura Kenji , Kawai Akihito , Miyamoto Takuma , Nakayama Syunsuke , Minami Naoki , Okada Hiroshi , Tanaka Yasuhito 
Published: October 2023

Case:
A 46-year-old man with vascular Ehlers-Danlos syndrome (EDS) had an open ankle fracture with a 10 × 5-cm skin defect on the medial side of the ankle. The patient underwent open reduction and internal fixation, as well as coverage of the skin defect with a posterior tibial artery perforator flap, which led to successful outcomes.

Conclusion:
We present the successful implementation of a posterior tibial artery perforator flap for the reconstruction of skin defects in a patient with vascular EDS. Despite the fragility of soft tissues, favorable surgical outcomes were observed.
Performance Benchmarking of Different Methods to Solve Gauss-Newton Trust Region Subproblems
Authors: Gao Guohua , Florez Horacio , Vink Jeroen , Blom Carl , Wells Terence J. , Saaf Jan Fredrik Edvard 
Published: October 2023

Summary
The Gauss-Newton (GN) trust region optimization methods perform robustly but may introduce significant overhead cost when using the conventional matrix factorization method to solve the associated GN trust region subproblem (GNTRS). Solving a GNTRS involves solving a nonlinear equation using an iterative Newton-Raphson (NR) method. In each NR iteration, a symmetric linear system can be solved by different matrix factorization methods, including Cholesky decomposition (CD), eigenvalue decomposition (EVD), and singular value decomposition (SVD). Because CD fails to factorize a singular symmetric matrix, we propose solving a GNTRS using the robust EVD method.
In this paper, we analyze the performances of different methods to solve a GNTRS using different matrix factorization subroutines in LAPACK with different options and settings. The cost of solving a GNTRS mainly depends on the number of observed data (m) and the number of uncertainty parameters (n). When n≤m, we recommend directly solving the original GNTRS with n variables. When n&gt;m, we propose an indirect method that transforms the original GNTRS with n variables to a new problem with m unknowns. The proposed indirect method can significantly reduce the computational cost by dimension reduction. However, dimension reduction may introduce numerical errors, which, in turn, may result in accuracy degradation and cause failure of convergence using the popular iterative NR method. To further improve the overall performance, we introduce a numerical error indicator to terminate the iterative NR process when numerical errors become dominant.
Finally, we benchmarked the performances of different approaches on a set of testing problems with different settings. Our results confirm that the GNTRS solver using the EVD method together with the modified NR method performs the best, being both robust (no failure for all testing problems) and efficient (consuming comparable CPU time to other methods).
The role of cities in Turkish relations with China
Authors: Kamiński Tomasz , Turan Ishak , Aral Neşe , Doğan Merve 
Published: October 2023

Abstract
State-level development of relations with China is usually accompanied by an increased number of contacts on the sub-state level, but the academic literature on Sino-Turkish relations has mainly been reticent on this phenomenon. This paper examines the sub-state level and attempts to characterise city-to-city contacts with China from the Turkish perspective. Based on data gleaned from a survey of 81 Turkish cities, we answer questions about the scope and the patterns of cooperation between Turkish and Chinese cities; we identify the main factors influencing this cooperation; and we argue that the Turkish government might use city-to-city relations to reach its policy goals towards China. Our findings show that Turkey's city-to-city relations with China are less developed than are the EU member states', and Sino-Turkish cooperation is currently far below its potential – particularly in business. However, city diplomacy is a hidden capacity in Turkish foreign policy, and the development of subnational links with China might be instrumental to Turkey in reaching its foreign policy goals.