bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oceanimonas pelagia sp. nov., a novel biosurfactant producing and plastic-degrading potential bacterium isolated from marine coastal sediment
Authors: Yang Hsiao-Tsu , Huang Yi-Hsuan , Ho Ying-Ning 
Published: November 2023

Abstract
A marine bacterial strain, designated as NTOU-MSR1T, was isolated from the marine sediment of Taiwan's northern coast. This bacterium is Gram-stain-negative, aerobic, and motile. It possesses a single flagellum, and its cells are rod-shaped, with an approx­imate width of 0.5-0.6 µm and a length of 1.8-2.0 μm. Growth is observed at 10-45℃ with an optimum at 30℃. The pH range for growth is 7.0-10.0, with optimal growth at pH 7.0-8.0. The cells can grow with a concentration of NaCl up to 12%. In the cell membrane, the predominant fatty acids are C16:1ω7c, C18:1ω7c, and C16:0. The overall genome relatedness indices indicate that strain NTOU-MSR1T has an average nucleotide identity (ANI) of 87.88% and a digital DNA-DNA hybridization (dDDH) value of 35.40% with its closest related species, O. marisflavi 102-Na3ᵀ, both values failing below the 95% and 70% species threshold. This indicates that strain NTOU-MSR1T is a novel member belonging to the Oceanimonas genus. The genomic DNA G+C content is 61.0 mol%. Genomic analysis uncovers the presence of genes associated with the catechol branch of β- ketoadipate pathway for polycyclic aromatic hydrocarbons (PAH) degradation, heavy metal resistance, production of poly(hydroxybutyrate)(PHB). In addition, strain NTOU-MSR1T has been found to possess the ability to synthesize biosurfactants and have a potential ability of plastic degradation. A proposed name, Oceanimonas pelagia, was assigned to this novel species, and the type strain of this bacterium was designated as NTOU-MSR1T (=BCRC 81403ᵀ=JCM 36023ᵀ).
Evaluation of Circulating Levels of miR-135a and miR-193 in patients with sepsis
Authors: behroozizad Nazila ,   Ata Ata Mahmoodpoor1, Shadvar Kamran , Ardebil Roghayeh Asghari , Sohrabifar Nasim Nasim , Kazeminasab Somayeh 
Published: November 2023

Abstract

Background
Sepsis is a life-threatening condition that the early diagnosis and prognostic awareness provide direction for selecting the appropriate treatment strategies. A wide variety of biomarker-based studies in clinical medicine provide new insights into the personalized medicine in sepsis patients. MiRNAs are endogenous non-coding RNA molecules which have been acting as the great potential diagnostic, prognostic and therapeutic biomarkers in diseases.
Methods and Results
In present study, the expression levels of two selected miRNAs, including miR-135a and miR-193, were evaluated for their prognostic potential in patients with sepsis. The circulating levels of miRNAs were quantified by quantitative PCR (qPCR) in patients with sepsis (n = 100) and age- and sex-matched healthy controls (n = 100). Statistical findings confirmed the valuable prognostic potential of miR-135a in patients with sepsis, while no significant difference was found between the miR-193 expression level in the patients with sepsis and controls.
Conclusions
Circulating level of miRNA-135a can serve as the prognostic biomarker for patients with sepsis. These findings highlight the importance of miRNAs as signatures in the personalized managements of sepsis.
Effects of illness perception and coping on self-management in peritoneal dialysis patients: A cross-sectional study
Authors: Zhang Man , Hai Ziwei , Du Yixin , Jiang Menghan , Cai Chunfeng 
Published: November 2023

Abstract
Aims
Chronic disease self-management is critical to disease prognosis and patient quality of life. Several psychological factors influence this process of self-management. In this background, the present study investigated the impact of illness perceptions and coping styles on self-management in people with peritoneal dialysis (PD).
Methods
The study is a cross-sectional study. From May 2022 to January 2023, a convenience sampling method was used to recruit 246 peritoneal dialysis patients. General information questionnaire, brief illness perception questionnaire, medical coping modes questionnaire and the self-management scale for peritoneal dialysis patients were used in this study. We used SPSS 24.0 to analyze the data, and the statistical methods included descriptive analysis, single factor analysis, Pearson correlation analysis and multiple linear regression analysis.
Results
A total of 246 patients were included in this study (93.89% response rate). Participants reported higher emotions and concerns about illness, while understanding of illness was low. Illness perceptions were negatively significantly correlated with self-management. With regard to coping styles, our patients were more likely to adopt avoidance and resignation coping styles. Confrontation and avoidance were positively related to self-management, while acceptance-resignation was negatively related.
Conclusions
Self-management of peritoneal dialysis patients needs to be improved. Age, female sex, monthly income, illness perceptions and coping styles were independently associated with self-management.
Impact:
These findings suggest that interventions that improve illness perceptions and coping styles should be explored to ultimately improve their self-management.
Patterns of Prevalence for Cardiovascular Diseases in Women of Childbearing Age, from 1990–2019 in Global, Regional and National: An Age-Period-Cohort Analysis
Authors: Hu Ben , Feng Jun , Wang Yuhui , Fan Yinguang , Hou Linlin 
Published: November 2023

Abstract
Background:Epidemiological studies on cardiovascular diseases (CVD) among women of childbearing age (WCBA) remain scarce. Our research aims to delineate the prevalence trends of CVD within this population over the past three decades, considering age, period, and birth cohort dynamics.
Methods:Estimates of CVD prevalence for WCBA, along with their 95% uncertainty intervals (UI), were extracted from the Global Burden of Diseases 2019 (GBD2019). An age-period-cohort (APC) model was utilized to assess the annual percentage change (net drifts) in overall prevalence, annual percentage changes in prevalence for individual age groups (local drifts), and fitted longitudinal age-specific rates adjusted for age effects and period/cohort relative risks (period/cohort effect).
Results:In 2019, the global prevalence of CVD among WCBA was 53.42 million (95% UI: 47.77 to 60.18). Eight countries recorded a prevalence exceeding one million, accounting for 54.17% of the global CVD prevalence in WCBA. Over the past 30 years, the annual net drift in CVD prevalence among the global WCBA was 0.27% (95% CI: 0.25 to 0.29). This value was 0.01% (95% CI: -0.04 to 0.06) in regions with a high sociodemographic index (SDI) and 0.21% (95% CI: 0.19 to 0.22) in those with a low SDI. Seventy-seven countries demonstrated an increasing trend in CVD prevalence, while 53 showed a decrease, and 74 remained relatively stable. Notably, as shown in local drift, there was a rise in CVD prevalence among adolescents aged 15-19 and adults aged 40-49 in regions categorized by five distinct SDI levels. This drift varied by SDI regions. Regions with a high SDI consistently had elevated period risks throughout the study duration, while other regions had lower period risks until 2000-2004 and displayed increased adverse period risks. The prevalence in low-middle and low SDI regions manifested detrimental trends, whereas other regions demonstrated an initial decline followed by a surge in successive birth cohorts.
Conclusions: Resources dedicated to CVD care for WCBA are largely insufficient, especially in low SDI regions. Thus, there is an urgent need to allocate cardiovascular healthcare resources variably across different SDI regions, aiming to diminish risks among successively younger birth cohorts. Throughout this endeavor, the formulation of targeted policies and the judicious distribution of resources are essential to reduce risks for women across all age groups.
The Effects of Contract Mechanisms between the Government and Private Hospitals on the Social Utility
Authors: Teymourifar Aydin , Kaya Onur , Ozturk Gurkan 
Published: November 2023

Abstract
In this work, we deal with a real healthcare system, in which public and private hospitals with different characteristics co-exist. While public hospitals have lower costs, they also suffer from long waiting times, diminishing the perceived quality of care for patients. Conversely, private hospitals, with their higher fees, offer shorter waiting periods, resulting in a more favorable perception of quality. A balanced healthcare system could offer societal benefits. Pricing strategies greatly influence a patient's hospital selection. For instance, reduced fees in private hospitals attract more patients, consequently reducing overcrowding in public facilities and elevating the overall quality of services provided. This study aims to develop pricing models to foster a balanced and socially advantageous healthcare system. Within this system, private hospital pricing is determined through contract mechanisms with the government. Thus, we delve into the ramifications of various contract models between the government and private hospitals on social utility. Our findings underscore the communal advantages of contract mechanisms. Furthermore, we generalize the proposed models to be applicable to similar systems.
Bifurcation analysis of delayed predator–prey system with fear effect, additional food for predator, prey refuge and predator age structure
Authors: Mo huazhou , Shao Yuanfu 
Published: November 2023

Abstract
In this paper, we construct a predator-prey model that includes fear, prey refuge, anti-predator behavior, predator age structure, and additional food. We examine certain basic properties of the system, such as positivity and uniformboundedness. Additionally, we study the conditions for the existence and stability of all equilibrium points, and obtainthe conditions and threshold values for local bifurcations triggered by various parameters through computations (fear, refuge coefficient, food quantity, juvenile predator coefficient and natural mortality rate of predator). Following that, we investigate the influence of all combinations of delay factors (fear on the prey's growth rate and gestation period of the predator population) on the stability of the proposed system. Finally, we performed numerical simulations to validate our theoretical research results and provide a detailed understanding of the influences of these parameters on the dynamics of the system. The results indicate that fear, prey refuge, additional food, and age structure distribution all play a key role in population stability.
Mathematics Subject Classification (2010). 34C23; 92D25.
Fiscal Rules and Green Investments in Developing Countries
Authors: CREPIN HISGUIMA DASSIDI 
Published: November 2023

Abstract
This study highlights the effect of Fiscal Rules(FR) on Green Investments(GI) in developing countries. We analyze the causal effect of adopting rules on green financing using the entropy balancing method in 78 countries. Two hypotheses are tested in this study. The first one states that adopting Fiscal Rules increases green financing, and the second one is related to the ability of different types of rules to attract more investments to fight climate change. First, the results are robust and show that adopting Fiscal Rules increases climate finance. Unlike expenditure rules, deficit, debt, and revenue rules positively affect green financing. The effect of Fiscal Rules on green finance is amplified in countries with strong economic performance, high levels of democracy, good- quality institutions, and a well-functioning state apparatus. On the other hand, the effect of the rules is mitigated in the presence of high natural resource rents.
JEL Classification : E60 ; E62 ; Q5
Translation and validation of the “Moral Injury Symptom Scale-Healthcare Professionals” in Greek
Authors: Moisoglou Ioannis , Katsiroumpa Aglaia , Konstantakopoulou Olympia , Karatza Athena , Gallos Parisis , Galanis Petros 
Published: November 2023

Abstract
Background
Stressful events occur several times during work among healthcare professionals. Especially, during the COVID-19 pandemic, healthcare professionals have had to deal with a variety of ethical dilemmas causing high levels of moral injury.
Aim
To translate and validate the “Moral Injury Symptom Scale-Healthcare Professionals” (MISS-HP) in Greek.
Methods
We conducted our study with 345 nurses in Greece during August 2023. We employed the forward-backward method to translate the MISS-HP in Greek. We examined the construct validity of the MISS-HP by performing confirmatory factor analysis. We estimated concurrent validity of the MISS-HP by comparing it with the “Moral Distress Thermometer” (MDT), the “Quiet Quitting Scale” (QQS), and single item burnout measure.
Results
We found that the MISS-HP had exceptional reliability since all intraclass correlation coefficients in test-rest reliability analysis were higher than 0.990. Moreover, all correlations were statistically significant (p < 0.001 in all cases). Additionally Cronbach’s coefficient alpha for the MISS-HP was 0.636. Our CFA confirmed the three-factors structure of the Greek version of the MISS-HP: guilt/shame factor, spiritual troubles factor, and condemnation factor. All model fit indices in CFA were excellent. In particular, x2/df was 1.316, RMSEA was 0.030, GFI was 0.979, AGFI was 0.959, TLI was 0.975, IFI was 0.985, NFI was 0.939, and CFI was 0.984. We found that the concurrent validity of the Greek version of the MISS-HP was very good. In particular, we found statistically significant correlations between the MISS-HP and MDT (r = 0.46, p < 0.001), QQS (r = 0.41, p < 0.001), and the single item burnout measure (r = 0.11, p < 0.04).
Conclusions
The “Moral Injury Symptom Scale-Healthcare Professionals” is a reliable and valid tool to measure moral injury among healthcare professionals.
The immunometabolic gene N-Acetylglucosamine Kinase (NAGK) is uniquely involved in the heritability of multiple sclerosis severity
Authors: Nataf Serge 
Published: November 2023

Abstract
The clinical severity of multiple sclerosis (MS), an autoimmune disorder of the central nervous system, is thought to be determined by environmental and genetic factors. In their genome wide association study (GWAS), Harroud et al.1 identified a single nucleotide polymorphism (SNP), rs10191329, which is associated with MS severity in two large independent cohorts of MS patients. Different approaches were followed by the authors to prioritize the targeted genes which are transcriptionally regulated by such a SNP. It was concluded that the identified SNP regulate a group of proximal genes involved in brain resilience and cognitive abilities rather than immunity. Here, by conducting an alternative strategy for gene prioritization, we reached the opposite conclusion. According to our re-analysis, the main target of rs10191329 is N-Acetylglucosamine Kinase (NAGK), a metabolic gene recently shown to exert major immune functions.
Runoff time series prediction based on hybrid models of two-stage signal decomposition methods and LSTM for the Pearl River in China
Authors: Guo Zhao , Zhang Qian-Qian , Li Nan , Zhai Yun-Qiu , Teng Wen-Tao , Liu Shuang-Shuang , Ying Guang-Guo 
Published: November 2023

Abstract

Hydrological runoff prediction is vital for water resource management. The non-linear and non-stationary runoff series and the complex hydrological features for large-scale basins make it difficult to predict. Long short-term memory (LSTM) is effective for runoff prediction but unstable for large-scale basins. This study develops three hybrid models combined with two-stage decomposition and LSTM, including wavelet transformation (WT) combined with complete ensemble empirical mode decomposition with adaptive noise (CEEMDAN), variational mode decomposition (VMD), and local mean decomposition (LMD), to predict the daily runoff of the Pearl River in China. The results indicate CEEMDAN's broader signal decomposition applicability for runoff series preprocessing, while VMD is simpler to extract high-runoff characteristics. VMD–WT–LSTM is appropriate for predicting high and median runoff, whereas CEEMDAN–WT–LSTM is better for low-runoff and high and median runoffs with low-violent fluctuations. These hybrid models provide satisfactory predictions for NSE and R2 indicators, and 97.2% of indicators fall within the acceptable range for high-runoff predictions. The hybrid models outperform traditional and standalone models in high-runoff but none of the decomposition methods in this research can identify low-runoff sub-sequence. This study provided runoff prediction methods requiring fewer data and processing time, and these methods are promising alternatives for daily runoff prediction in large-scale basins.
Removal of methyl orange textile dye using magnetic chitosan microspheres adsorbent
Authors: Estefan Erik , Elystia Shinta , Kuan Wen-Hui , Sasmita Aryo 
Published: November 2023

Abstract
Industrial textile wastewater contains high levels of dyes, which are potentially harmful to aquatic ecosystems by inhibiting sunlight penetration for photosynthesis activities. Adsorption is a simple method for pollutant removal for water treatment. Magnetic Chitosan Microspheres (MCM) has been developed as a natural adsorbent for dye removal. This study aimed to compare the properties of the raw adsorbent and after adsorption by FT-IR, BET, DLS, and SQUID Magnetometry. The adsorption behaviours were investigated by the influence of pH, contact time, and initial concentration on Methyl Orange removal. The result was MCM could eliminate MO until 93.60% at pH 7 with C0 100 mg L−1 in 5 min with an adsorption capacity of 187.21 mg g−1. Adsorption processes were also studied through the isotherm and kinetic. The isotherm showed a closer fit to the Langmuir model than the Freundlich model. The kinetic result showed the PSO model was more suitable than PFO. The research data using MCM for adsorption demonstrated excellent adsorption capability in terms of dye removal percentage and high adsorption capacity. Therefore, this material could be an effective adsorbent for the treatment of dye-containing wastewater.
Genetic parameters for lifetime productivity in Holstein and Brown Swiss dairy cows in Honduras
Authors: Copas-Medina Karen Alessa , Valladares-Rodas Manuel , Baeza-Rodríguez Juan José , Segura-Correa José Candelario , Magaña-Monforte Juan 
Published: November 2023

Objective. To estimate the heritability (h2) of age at first parturition (AFP), longevity (L), useful life (UL), and productivity (P), as well as the genetic (rg) and phenotypic correlations between those traits in Brown Swiss and Holstein cows in Northwestern Honduras. Materials and methods. Cattle were raised under tropical conditions and intensive management. The model for AFP assessed the effect of contemporary group (herd, year and birth season combination) as fixed. The model used for L, UL and P included the contemporary group, age group at first calving and their interaction. Data were analyzed using restricted maximum likelihood procedure, adjusted to a univariate and to a bivariate animal model. Results. The h2 estimated for AFP, L, UL and P were 0.16, 0.18, 0.25 and 0.09, respectively, in Brown Swiss cows, and 0.53, 0.49, 0.7 and 0.22, respectively in Holstein. Negative but favorable rg among Brown Swiss cow traits ranged from 0.31 to 0.46 between AFP and the other traits. However, for Holsteins cows, positive rg among AFP and the other traits here studied varied from 0.49 to 0.96. In both cattle breeds, rg among L, UL and P, traits were positive. Conclusions. For all traits evaluated low to medium heritability’s for BS suggest that a slow genetic improvement could be achieved if independent selection of traits is applied, and better response could be expected for H breed. For both breeds the positive rg among L, UL and P suggest thar similar selection criteria could be used.
Association of eGFR and Albuminuria with Venous Thromboembolism
Authors: Zheng Zhong , Pandit Krutika , Chang Alex R. , Shin Jung-Im , Charytan David M. , Grams Morgan E. , Surapaneni Aditya 
Published: November 2023

Background
CKD has been implicated as a risk factor of venous thromboembolism, but the evidence is limited to relatively healthy populations. The objective of this study was to discern whether parameters of kidney function and damage are associated with the occurrence of venous thromboembolism after hospitalization.

Methods
We conducted a retrospective study including 23,899 and 11,552 adult individuals hospitalized within Geisinger Health System and New York University (NYU) Langone Health from 2004 to 2019 and 2012 to 2022, respectively. A Poisson model was used to evaluate adjusted incidence rates of venous thromboembolism according to eGFR and albuminuria categories in each cohort. Cox proportional hazards models were used to analyze associations of eGFR and urinary albumin-to-creatinine ratio (UACR) with venous thromboembolism, and hazard ratios (HRs) were meta-analyzed across cohorts.

Results
Both lower eGFR and higher UACR were associated with higher risks of venous thromboembolism. In the Geisinger cohort, the incidence of venous thromboembolism after hospital discharge ranged from 10.7 (95% confidence interval [CI], 9.2 to 12.6) events per 1000 person-years in individuals in G1A1 (eGFR >90 ml/min per 1.73 m2 and UACR <30 mg/g) to 27.7 (95% CI, 20.6 to 37.2) events per 1000 person-years in individuals with G4-5A3 (eGFR <30 ml/min per 1.73 m2 and UACR >300 mg/g). A similar pattern was observed in the NYU cohort. Meta-analyses of the two cohorts showed that every 10 ml/min per 1.73 m2 reduction in eGFR below 60 ml/min per 1.73 m2 was associated with a 6% higher risk of venous thromboembolism (HR 1.06 [95% CI, 1.02 to 1.11], P = 0.01), and each two-fold higher UACR was associated with a 5% higher risk of venous thromboembolism (HR 1.05 [95% CI, 1.03 to 1.07], P < 0.001).

Conclusions
Both eGFR and UACR were independently associated with higher risk of venous thromboembolism after hospitalization. The incidence rate was higher with greater severity of CKD.

Podcast
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Aplicación de la Jurisprudencia que establece la Improcedencia del Juicio de Amparo en contra del nombramiento del cargo de Rector en las Universidades Públicas Autónomas
Authors: Vázquez Acuña Félix 
Published: November 2023

En este estudio se analizan las cinco ejecutorias con las que se estableció la jurisprudencia que nos lleva a afirmar que su correcto alcance debe ser el de considerar improcedente el juicio de amparo contra el nombramiento del cargo de Rector, cuando la ley de creación de la universidad contemple la facultad de un órgano interno para efectuar dicha designación y, por tanto, no se deberá establecer la causal de improcedencia si la facultad no sólo no se contempla, sino que se prevea al voto libre, secreto y directo de la comunidad universitaria como fuente para la elección de la referida autoridad.