bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dual anti-CTLA-4 and anti-PD-1 blockade in metastatic basal cell carcinoma
Authors: Patel Sandip P. , Cano-Linson Eleanor , Chae Young Kwang , Schokrpur Shiruyeh , Lao Christopher D. , Powers Benjamin C. , Victor Adrienne I. , Onitilo Adedayo A. , Shin Sarah , Takebe Naoko , Threlkel Sara , McLeod Christine M. , Chen Helen X. , Sharon Elad , Othus Megan , Ryan Christopher W. , Blanke Charles D. , Kurzrock Razelle 
Published: January 2025

Abstract
We report the basal cell cancer (BCC) cohort of the SWOG/NCI 1609 Dual Anti-CTLA-4 & Anti-PD-1 blockade in Rare Tumors (DART), a phase II prospective, multicenter basket trial of nivolumab and ipilimumab. The primary endpoint was objective response rate (ORR) (RECIST v1.1). Overall survival (OS), progression-free survival (PFS), and toxicity were secondary endpoints. Sixteen patients with advanced/metastatic BCC were evaluable. The ORR was 31% (95% CI, 19–50%), and the 12-month OS, 75% (95% CI, 57–100%). Median PFS was 9.3 months (95% CI, 3.3–NA). Of 15 patients evaluable for clinical benefit, five partial responses (PRs) and five stable disease >6 months (total = 10/15 (66.7%)) were seen. The most common toxicities included fatigue (37.5%), pruritis (31.3%), and diarrhea (25%). In patients with advanced/metastatic BCC, ipilimumab and nivolumab produced an ORR of 31% and prolonged (>6 months) PFS in 73% of patients, with seven PFS/iPFS of >1 year, including one with prior anti-PD-1. ClinicalTrials.gov ID: NCT02834013 (Registered 7/15/2016; https://clinicaltrials.gov/ct2/show/NCT02834013).
Pluvial flood impacts and policyholder responses throughout the United States
Authors: Nelson-Mercer Benjamin , Kim Taeho , Tran Vinh Ngoc , Ivanov Valeriy 
Published: January 2025

Abstract
Pluvial floods pose a significant threat to properties, yet comprehensive impact analysis is hindered by data limitations on pluvial inundation. To assess pluvial flood impacts, we leveraged U.S. flood insurance claims and policy records for a subset of properties outside 100-year floodplains, streamflow records, and nationwide precipitation data, enabling us to distinguish damage claims caused by pluvial floods over 1978–2021. Strikingly, 87.1% of the claims analyzed from this subset were due to pluvial floods. Utilizing these pluvial flood claims unveiled distinct regional patterns of pluvial impacts across the contiguous U.S. These patterns are informed by the relationship between claim frequency and precipitation within each region. Remarkably, despite the pervasiveness of impacts, many states are seeing declining uptake in pluvial flood insurance coverage. Our study highlights regions facing heightened pluvial flood risks and underscores the critical need for enhanced consideration of pluvial inundation within risk management frameworks.
Life Impact of Cluttering: The Adult Perspective
Authors: Giuffre Lisa A. , Scaler Scott Kathleen 
Published: January 2025

Introduction:

Though the research on the quality of life of people who stutter is extensive, there is minimal research on cluttering's life impact. Anecdotal reports from people who clutter

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and their significant others have described some elements of cluttering's impact and advocated for these components to be addressed in treatment. Three formal studies have used semistructured interviews to document cluttering's impact. These non–peer-reviewed studies make important contributions; however, more research is needed to add to this existing information. The current study adds perspectives of adults who clutter related to cluttering's impact upon the specific contexts of work, school, and social situations.

Method:
In this phenomenological study, 10 adults who clutter participated in a semistructured interview. Through grand tour, mini tour, and example questions, participants were asked to provide their perspective on the life impact of cluttering. Each interview was orthographically transcribed, and transcripts were coded for themes. Triangulation and member checking were conducted to establish reliability and validity of themes.

Results:
Results revealed the following themes: Social impact of cluttering leads to avoidance, misunderstanding, and feelings of isolation; cluttering impacts natural tendencies; educational impact of cluttering results in misunderstanding and struggle; occupational impact of cluttering leads to role entrapment and difficulty maintaining employment.

Conclusions:
This study adds perspectives of adults who clutter regarding specific aspects of quality of life such as social isolation, frequent misunderstandings, and negative educational and occupational impact. As more voices are heard within the cluttering community, more support is presented for the importance of understanding the negative life impact cluttering can have. Further understanding of these perspectives adds to the information needed to inform holistic cluttering assessment and treatment.
The crime drop in South Africa: an exploratory research note
Authors: Breetzke Gregory D. , Girmay Luna Asefaw 
Published: January 2025

Abstract
Research examining the crime drop has become increasingly popular with a plethora of studies showing how crime has declined since the 1990s. The vast majority of this research has, however, emanated from the United States and other ‘Western’ countries. In this study, we undertook a national-level analysis of crime trends in South Africa from 2010 to 2019 using official police data. Results showed that crime did drop marginally in the country over the study period although there is substantial variability in crime decline by crime type and geography. Moreover, various socio-demographic characteristics, such as income inequality, were found to possibly influence the temporal trends of crime in the country observed. These findings underscore the importance of context-specific analyses in understanding decadal crime trends and highlight the need for targeted, geographically nuanced approaches to crime prevention in South Africa.
Scholarly authors as self-translators
Authors: Elsherif Garda 
Published: January 2025

Abstract
This paper examines traces of (self-)translation in the work of the Egyptian philosopher Hasan Hanafi (1935–2021),
whose academic career reflects the increasing globality of the academic field. The paper analyses Hanafi’s academic migration to
France to complete his doctorate, his self-translational efforts to adapt to the French academic tradition, and the influence of
his (physical and linguistic) migration on his later philosophical texts in Arabic. Hanafi was convinced that the ‘archaic’ Arabic
language alienated Muslims from their own heritage, and in his later philosophical texts he thus sought to renew the Arabic
language and to re-express fundamental concepts of the classical Islamic teachings. The concepts he aimed to re-express were
already translated into French in his doctoral thesis. This article addresses these terminological translations into French and
back into Arabic, and discusses the conceptual transformations that occurred on the way, inspired by Hanafi’s reading of Husserl
and the German Idealists.
Use of a mechanical roller-crimper as an alternative kill method for cover crops
Authors: Ashford Dana L. , Reeves D. Wayne 
Published: January 2025

AbstractCover crops have long been recognized as a beneficial component of many cropping systems; however, their use is still not commonplace. Usage may be increased by identifying more cost-effective and environment-friendly techniques for cover-crop management. This study was conducted to determine the effectiveness of using a mechanical roller-crimper as-an alternative method for killing cover crops. The study location was in east-central Alabama, using a split-split plot experimental design with four replications and 3 site-years during 1999–2000. Rye, wheat and black oat were evaluated in terms of ease of kill and optimum time of kill using a roller-crimper, two herbicides (paraquat and glyphosate) at their labeled rate, and two reduced chemical (half label rate) combinations of the same chemicals with the roller-crimper. Four Feekes' scale growth stages were used to determine optimum time of kill; 8.0 (flag leaf), 10.51 (anthesis), 10.54 (early milk) and 11.2 (soft dough). Plant growth stage was the main determining factor for effectiveness of the roller-crimper for killing the cover crops. At the flag leaf stage, the roller-crimper provided only 19% kill across all covers over the 3 site-years. After plants reached anthesis, the roller-crimper with half-rate herbicide combinations equaled the effectiveness of herbicides alone at their label rate, averaging 94% kill. By the soft dough growth stage, all kill methods were equally effective due to accelerating plant senescence (95% mean kill across kill methods). Use of the roller-crimper alone after anthesis can decrease costs by as much as $26.28 per ha, while providing a kill rate equivalent to that of herbicide treatment alone.
On the multi-q characteristics of magnetic ground states of honeycomb cobalt oxides
Authors: Gu Yuchen , Jin Xianghong , Li Yuan 
Published: January 2025

Abstract
The Kitaev honeycomb model has received significant attention for its exactly solvable quantum spin liquid ground states and fractionalized excitations. For realizing the model, layered cobalt oxides have been considered a promising platform. Yet, in contrast to the conventional wisdom about single-q zigzag magnetic order inferred from previous studies of the Na2IrO3 and α RuCl3 candidate materials, recent experiments on two of the representative honeycomb cobalt oxides, hexagonal Na2Co2TeO6 and monoclinic Na3Co2SbO6, have uncovered evidence for more complex multi-q variants of the zigzag order. This review surveys on experimental strategies to distinguish between single- and multi-q orders, along with the crystallographic symmetries of the cobalt oxides in comparison to the previously studied systems. General formation mechanism of multi-q order is also briefly discussed. The goal is to provide some rationales for examining the relevance of multi-q order in the honeycomb cobalt oxides, along with its implications on the microscopic model of these intriguing quantum magnets.
Signatures of the speed of sound on the gravitational wave power spectrum from sound waves
Authors: Giombi Lorenzo , Dahl Jani , Hindmarsh Mark 
Published: January 2025

Abstract
Future space-based interferometers offer an unprecedented opportunity to detect signals from the stochastic gravitational wave background originating from a first-order phase transition at the electroweak scale. The phase transition is accompanied by a change of the equation of state from that of pure radiation. In this work we study the effect of this change on the power spectrum of gravitational waves generated by the sound waves in the plasma during the acoustic phase of the transition. We carry out an analytic calculation assuming that the sound speed and the fluid shear-stress that sources tensor perturbations remain approximately constant during the acoustic phase. The effect of a softer equation of state is twofold:
(i) a scale-independent suppression of the power spectrum at all scales, due to the modified propagation of both sound and gravitational waves and
(ii) the peak of the spectrum moves to smaller frequencies as the equation of state becomes softer.
The power-law indices of the spectrum at small and large scales are unaffected by the softening of the equation of state. Our work improves the current estimation of the gravitational waves power spectrum from first order phase transitions and expands the possible scenarios of transitions that can be tested by gravitational wave detectors.
Axi-Higgs portal dark matter via Wess-Zumino mechanism
Authors: Anilkumar Akshay , Arun Mathew Thomas , Nair Arjun S. 
Published: January 2025

Abstract
We study the axion portal between the visible and the dark sector, where the dark matter is charged under an abelian extension of the Standard Model. In general, such models are anomalous and are rendered gauge invariant by a Stückelberg axion through Wess-Zumino/Green-Schwarz mechanism. Scenarios such as this naturally exist in TeV scale string theory completions of Standard Model. This axion mixes with other Goldstone bosons in the model to give a physical axi-Higgs which becomes massive upon breaking the anomalous gauge group. Such axi-Higgs fields charged under the anomalous symmetry act as mediators for the dark matter annihilation to Standard Model particles and can lead to an efficient freeze-out mechanism. Here, we show that the Stückelberg axion, and the resultant axi-Higgs, with its appropriate shift symmetry cancels the quantum anomalies and also generates the observed relic density for the dark matter. Moreover, we show that the relevant parameter space in our model, where photon production dominates, is safe from FermiLAT, Cherenkov Telescope Array, and H.E.S.S. indirect detection experiments.
Computational microscopy with the PERCIVAL detector system at TwinMic beamline
Authors: Guzzi Francesco , Gianoncelli Alessandra , Stebel Luigi , Giuressi Dario , Cautero Giuseppe , Borghes Roberto , Gregori Iztok , Billè Fulvio , Scarcia Martin , Bonanni Valentina , Žižić Milan , Hyun HyoJung , Nichols William , Correa Jonathan , Marras Alessandro , Wunderer Cornelia B. , Graafsma Heinz , Menk Ralf Hendrik , Kourousias George 
Published: January 2025

Abstract
PERCIVAL is a novel soft X-ray detection system designed for the needs of modern microscopy. By integrating it into the TwinMic end-station at Elettra Sincrotrone Trieste, we conducted an exploratory computational microscopy experiment on biological samples, aiming at evaluating the entire system in a real use-case scenario. We present the methodology to convert the RAW data and our high-resolution image reconstructions.
An intra-pulse feedforward algorithm for improving pulsed microwave and beam stability
Authors: Zhu Jinfu , Ding Hongli , Han Jiawei , Li Haokui , Yang Jiayue , Zhang Weiqing 
Published: January 2025

Abstract
During the pulsed operation of the linear accelerator in
Dalian Coherent Light Source (DCLS), we observe a strong correlation
between the klystron modulator's high voltage and the klystron
output microwave, with noticeable stratification among
microwaves. Therefore, we propose an intra-pulse feedforward
algorithm and implement it in Low-Level Radiofrequency (LLRF)
systems. This algorithm assumes that the transfer model of the
microwave system is linear within a small range of work points and
measures the transfer coefficient of the microwave between the LLRF
and klystron. For each pulsed microwave of the klystron output, the
LLRF system first calculates the vector deviation between the
initial measurement within its pulse and the target. The deviation
will be compensated in the LLRF excitation so that the
stratification in the later part of the pulsed microwave is
suppressed. Experiments have shown that this algorithm can
effectively suppress the stratification among microwaves. The
microwave amplitude and phase stability (RMS) are improved from
0.10%/0.19∘ to 0.07%/0.06∘ (klystron 4, for
example), and the beam energy stability is significantly enhanced
from 0.14% to 0.08%. This algorithm can also be applied to other
FEL accelerators operating in pulsed modes.
Enhanced interannual variability of the terrestrial carbon sink in China under high emissions
Authors: Wu Han , Zhang Li , He Honglin , Ren Xiaoli , Zhang Mengyu , Chu Dingjin , Zheng Yuanhao 
Published: January 2025

Abstract
Interannual variability (IAV) of terrestrial carbon uptake is a major contributor to the variation of atmospheric CO2. With the influence of the East Asian monsoon, future climate variability would significantly increase in China. However, how these future changes will modulate the IAV of China’s terrestrial carbon sinks remains unclear. Here, we analyzed the IAV of China’s terrestrial net ecosystem productivity (NEPIAV) and investigated the potential impacts of climate change under various scenarios during the 21st century using the outputs from nine Coupled Model Intercomparison Project Phase 6 models. The results reveal that China’s terrestrial NEPIAV would be enhanced under higher emissions scenarios from 2015 to 2100. The standard deviation of national NEPIAV under the SSP585 scenario rises by 12% compared with SSP126. The most prominent contribution to this enhancement in the total NEPIAV comes from a larger NEP IAV in summer (10%), particularly in the subtropical–tropical monsoonal climate zone in China. Moreover, the enhancement is largely attributed to the intensified IAV in temperature and precipitation in the monsoonal climate zones as well as the heightened sensitivity to them, especially in the ecosystems of the subtropical–tropical monsoonal zone. Compared with monsoonal precipitation, IAV of temperature in the subtropical–tropical monsoonal climate zone also plays an important role in NEPIAV under higher emissions scenarios. Our results highlight the crucial influence of future fluctuations in monsoon climate systems on terrestrial carbon sink IAV and the urgency of reducing the uncertainties of Earth system models in predicting both climate in monsoon regions and the responses of carbon cycling processes to temperature.
Assessing mangrove forest changes using vegetation index algorithm in southern west Lombok
Authors: Sukuryadi  , Johari H I , Ibrahim  , Adiansyah J S , Nurhayati  
Published: January 2025

Abstract
The availability of multi-temporal remote sensing data, particularly satellite imagery combined with Geographic Information Systems (GIS), enables effective monitoring of changes in the condition and extent of mangrove forests. This study aims to analyze temporal changes in mangrove forests and evaluate their condition through a vegetation index analysis in southern West Lombok. The research methodology involves field observations and remote sensing data analysis, employing the Normalized Difference Vegetation Index (NDVI) as the primary vegetation index algorithm. The multi-temporal analysis focuses on three key years: 2001, 2008, and 2022, revealing significant changes in the mangrove ecosystem based on the classification of vegetation index values derived from Landsat satellite imagery. The findings indicate that by 2008, the mangrove ecosystem had experienced severe degradation, primarily due to land conversion for activities such as aquaculture and settlement development, as well as extensive logging by local communities for firewood and other uses.
The influence of social reference on the green social movement among youth in Indonesia
Authors: Kabbaro H , Mashabi N A , Arlianty L S , Zulfa V , Anesti F , Oktaviani A 
Published: January 2025

Abstract
This research analyzes social references’ influence on the youth green social movement. The sample in this research was selected using a survey sampling technique and involved 798 youth. Data was obtained using a questionnaire. The instrument used to measure social references consists of 12 statement items based on the dimensions of informational influence, utilitarian influence, and value-expressive influence. The instrument used to calculate the green social movement consists of 28 statement items based on actual commitment, verbal commitment, influence, and knowledge. The data was processed and analyzed using descriptive and inferential statistics. Based on the regression equation results, it can be seen that if the social reference variable is increased by one unit, the green social movement will increase by 0,658 at a constant of 66,237. This research shows a coefficient of determination with a value of R Square= 0.244. The Social Reference variable can explain 24.4% of the green social movement variant. Meanwhile, 75.6% is explained by other variables not determined in this research. These results show that the higher the social reference, the higher the green social movement.
Contribution of coffee farming and goat livestock based integration in Karo regency, north Sumatra province
Authors: Ginting A , Purba E , Chalil D , Diana N 
Published: January 2025

Abstract
This research evaluated the contribution of coffee farming and goat farming to farm income. It was conducted in Karo Regency, North Sumatra Province, where the Starbucks Farmer Support Center (SFSC) supported the area, which empowered farmers to develop an integrated farming system for coffee and goat farming. The sample size was determined using the census method, a sampling technique based on the Population size. The data analysis was performed descriptively, analyzing the income from coffee farming and goat farming and the contributions of each business to farmer income. The results indicated that the average income from coffee farming after integration was Rp 14,262,639.20, while goat farming generated an income of Rp 4,063,601.19. The efficiency of coffee farming was reflected in the R/C value of 4.92, compared to goat farming, which had an R/C value of 1.72. Coffee farming contributed 77.83% to farm income, whereas goat farming contributed 22.17%. Based on these findings, it was recommended that farmers increase the number of goats they raised to enhance both income and efficiency.
Secondary metabolite profile and free-radical scavenging activity of ethyl acetate extract of bidara fruit and leaves (ziziphus mauritiana)
Authors: Sugara T H , Fitriana Y , Koswara I , Fahrurrozi  , Chasanah E , Adam M A , Nurbaety B , Dewi E S , Hati M P , Furqani N 
Published: January 2025

Abstract

Ziziphus Mauritiana has high economic value but is still considered a nuisance plant for most people. Not only are the fruit and some parts of the Z. Mauritiana plant rich in nutrients, but they also contain bioactive compounds that can benefit health. This study aimed to provide information on the profile of secondary metabolites and free-radical scavenging activity of Z. Mauritiana fruit and leaf extracts. The study consisted of four stages: sample powder preparation, extraction process, phytochemical screening, and free-radical scavenging activity assay by DPPH (2,2-Diphenyl-1-picrylhdrazyl) method. The yield of ethyl acetate extract of Z. Mauritiana fruit and leaves obtained from the maceration process was 9.86 g (3.28%) and 12.92 g (4.30%), respectively. Phytochemical screening showed that ethyl acetate extract of Z. Mauritiana fruit and leaves contained flavonoids, tannins, terpenoids, and steroids. Both extracts showed free-radical scavenging activity in the strong category (IC50 = 50-100 ppm). The ethyl acetate extract of Z. Mauritiana leaves has better free-radical scavenging activity (IC50 = 66.09 ppm) than the fruit (IC50 = 73.39 ppm). The results showed that the fruit and leaves of Z. Mauritiana contain flavonoids, tannins, and terpenoids, which act as free radical scavengers and can be used as alternative food sources with potential antioxidant properties.