bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of moisture deficiency on the apple stress-associated protein expression level .
Authors: Kuzmitskaya Р. V. , Karaleva К. S. , Urbanovich О. Yu. 
Published: February 2024

In plants, stress-associated proteins (SAP) are involved in response to adverse biotic and abiotic factors. In order to study the drought effect on changes in the SAP expression level in apple trees and their involvement in stress response, an expression level of fourteen genes belonging to this family was analyzed using qPCR. Their participation in a stress response to drought in the genome of the MM-106 apple tree rootstock was shown. At that, the genes demonstrated a tendency to increase their expression by the fourth hour of drought exposure followed by its decrease by the twenty-fourth hour.A comparison of the data obtained during the described experiment with the data obtained when modeling drought under milder conditions showed that under more severe drought conditions, an expression of a greater number of gene encoding stress-associated proteins increases, and a more pronounced response occurs. Evaluation of the effect of an identity degree of nucleotide sequences of gene encoding stress-associated proteins on the similarity of their expression profiles under drought exposure did not reveal any direct relationship between the primary structure of genes and the nature of their expression.In the structure of stress-associated proteins encoded by the genes most strongly response to drought in Malus, Solanum lycopersicum, Gossypium hirsutum, and Cucumis sativus, the A20-AN1 type domain occurs more frequently than other types of zinc finger domains. Analysis of the similarity of stress-associated protein sequences and the expression levels of genes encoding them under drought conditions in different plant species (apple, cotton, tomato, and cucumber) suggests that in each species, the evolution of adaptation mechanisms, including SAP encoding genes, occurred independently and, most likely, after separation of those species from their common ancestor. The results obtained will make it possible to clarify the role of individual genes, encoding SAP, in the formation of an apple stress response to the drought effect.
“Dehumanization of man” is a key problem of the modern era
Authors: Golovach A. A. 
Published: February 2024

The human problem, which originally belongs to the number of fundamental problems of philosophy and culture, does not lose its significance today, but also acquires a special acuteness and, accordingly, relevance.The phenomenon of dehumanization, the concept of alienation, globalization and globalization processes are considered from the standpoint of historical determinism, when solving the tasks set, they turned to the ideas of K. Marks, E. Fromm, D. Lukach, T. Adulo, etc. When writing the article, methods of analysis, synthesis, induction, deduction, comparison were used. Globalization processes, which are a distinctive feature of all states and societies, combine an infinite number of aspects of social life that vary in scope – from local to planetary, while having different dynamics and orientation. Globalization and globalization processes are not the end or the stop of social processes. Dehumanization presupposes the degradation of morality. The research is based on conceptual provisions, ideas, results of the problem of dehumanization and the problem of alienation in the context of globalization, the publications of Russian and foreign authors on the stated topic are analyzed. The object of study is the problem of “dehumanization of man” and the topic of alienation in modern globalizing conditions.As a result of the analysis, certain vectors of the spiritual development of modern society are outlined in the conditions of a systemic crisis of value orientations and lack of spirituality, inhumanity. The article presents the outlines of new ethical programs that are designed to counteract the process of modern man’s loss of a genuine humane essence and his purpose in society.
Pengaruh Model Problem Based Learning Terhadap Kemampuan Komunikasi Matematis Siswa Kelas V SDN Kuken
Authors: Abadi M. Jodi Faerus , Zain Moh Irawan , Turmuzi Muhammad 
Published: February 2024

Matematika adalah ilmu pengetahuan memiliki kekayaan ide, diantaranya tidak membutuhkan pembuktian, hal tersebut yang menimbulkan konsep-konsep baru dalam matematika Penelitian ini bertujuan untuk mengetahui ada atau tidak adanya pengaruh model problem based learning terhadap kemampuan komunikasi matematis siswa Kelas V SDN Kuken. Penelitian ini menggunakan Metode penelitian kuantitatif eksperimen, jenis Quasi Eksperimental Design tipe one group pre-test post-test Design. Subjek dalam penelitian ini adalah seluruh siswa kelas V SDN Kuken. Teknik pengumpulan data yang digunakan adalah tes komunikasi matematis tertulis. Instrumen pengumpulan data dalam penelitian ini menggunakan tes komunikasi matematis tertulis dalam bentuk uraian sebanyak 5 butir soal yang telah memenuhi validitas. Uji hipotesis dalam penelitian ini menggunakan paired sampel t-test. Sebelum melakukan uji hipotesis data yang diperoleh di uji terlebih dahulu dengan uji normalitas data. Berdasarkan perhitungan pengujian hipotesis dengan uji t diperoleh (Sig) 0,00000001 pada taraf signifikansi 5%. Sehingga dapat disimpulkan bahwa diterima dan ditolak, dikarenakan nilai (Sig) dari uji t lebih kecil dari 0,05 atau bisa disebut 0,00000001 < 0,05 yang artinya terdapat perbedaan kemampuan komnikasi matematis tertulis antara sebelum dan setelah mendpat perlakuan model problem based learning. Berdasarkan hasil penelitian tersebut maka dapat disimpulkan bahwa model problem based learning berpengaruh terhadap kemampuan komunikasi matematis Siswa Kelas V SDN Kuken.
Hydrocarbon-Impacted Soils Supported Mn for Organic Pollutant Oxidation
Authors: Saputra Edy , Fadli Ahmad , Prawiranegara Barata Aditya , Amri Amun , Heltina Desi , Bahri Syaiful , Sandhyavitri Ari , Restuhadi Fajar , Abid Hussein Rasool , Azhar Muhammad Rizwan , Utama Panca Setia 
Published: February 2024

Hydrocarbon-impeded soil (HIS) is solid waste from spills or leaks during industrial activities that negatively impact the environment. This study aims to utilize HIS as catalyst support on MnO2 to degrade RhB (RhB) solution using Peroxymonosulfate (PMS) and to determine the optimum conditions for the catalyst to degrade RhB. The catalyst was synthesized by reacting HIS, calcined with KMnO4 with various catalyst supports with high and low Total contain Petroleum Hydrocarbon (TPH). The process degradation of Rhodamine Solution was carried out with various catalysts, PMS, and RhB concentrations. The catalyst was characterized using X-ray diffraction (XRD), Nitrogen gas adsorption-desorption (BET), and Scanning Electron Microscope-Energy Disperse Spectroscope (SEM-EDX). In this study, the best catalyst performance was MnO2@H-TPH, which could activate PMS to degrade RhB with dye removal of 98% in about 180 min, at conditions 10 g/L RhB, 0.1 g/L catalyst, and 3 g/L PMS with the activation energy of 16.3 kJ/mol.
Pelatihan Pembuatan Eco Enzym dengan Memanfaatkan Sampah Organik pada Kelompok Masyarakat Desa Samirono Kecamatan Getasan Kabupaten Semarang
Authors: Rifandi Raditya Ahmad , Haksasi Banun Sri , Marliyah Lili , Harini Harini 
Published: February 2024

Permasalahan persampahan menjadi masalah serius baik di kota maupun desa khususnya sampah organik termasuk di desa Samirono kecamatan Getasan kabupaten Semarang. Pengolahan sampah harus dilkukan secara komprehensif baik di hulu maupun di hilir. Pelibatan masyarakat dalam penanganan sampah menjadi salah satu kunci keberhasilan, Eco-Enzyme merupakan metode yang dapat digunakan dalam penanganan sampah organik menjadi memiliki nilai manfaat. Kegiatan pengabdian kepada masyarakat ini bertujuan mengeduksi masyarakat untuk dapat menangani sampah organik rumah tangga menjadi produk alami mulfifungsi baik sebagai cairan pembersih, desinfektan hingga pupuk organik dengan teknologi yang ramah lingkungan. Pembuatan Eco-Enzyme dengan memanfaatkan sampah organik dapat membantu masyarakat mengurangi pengeluaran, serta dapat berkontribusi dalam mengurangi pencemaran lingkungan dari zat kimia akibat penggunaan cairan pembersih dan desinfektan berbahan kimia sintesis. Metode pengabdian dilaksanakan dengan cara melakukan sosialisasi, pelatihan dan pendampingan membuat Eco-Enzyme. Kegiatan pengabdian ini dilakukan secara tatap muka langsung kepada masyarakat. Hasil dari kegiatan ini adalah masyarakat mampu secara mandiri membuat Eco-Enzyme dari sampah organik rumah tangga.
Ongoing History Writing in History Textbooks
Authors: Nyström Daniel 
Published: February 2024

Abstract
This article addresses the ways in which Swedish history textbooks for upper secondary schools published between 1994 and 2011 deal with the most recent past. The textbooks are chronologically organized and follow history into the textbook authors’ time, and each new edition of the textbooks includes the latest developments. The article inquires as to whether this gradual addition of events is to be regarded as historiography at all, or what the possible difference is between contemporary commentary and historiography. It examines which events and developments are selected, how they are presented, and how they can be interpreted with regard to periodization and the use of history.
Intracranial solitary fibrous tumor in a 15-year-old girl: illustrative case
Authors: Lu Kuan , Qu Xiaoqing , Jiang Jingcheng , Zheng Quanjun , Ao Yongsheng , Qiu Lihua 
Published: February 2024

BACKGROUND
Solitary fibrous tumor (SFT) is an infrequent spindle cell tumor derived from mesenchymal tissue, which can manifest in diverse anatomical locations, primarily in the pleural cavity and infrequently in the central nervous system. SFT is predominantly observed in individuals aged between 40 and 50 years old, with a slightly higher occurrence in males than in females.

OBSERVATIONS
This case report describes a female, age 15, who had migraines for 2 months prior to the diagnosis of an intracranial tumor. Computed tomography and magnetic resonance imaging showed a mass located in the right parietooccipital region with surrounding edema and a compressed right lateral ventricle. Neurosurgery was utilized to successfully remove the mass, and single intracranial fibrous tumor (grade I) was identified by postoperative pathological analysis. During an 8-month follow-up period, the patient did not experience any recurrences.

LESSONS
SFT is often misdiagnosed as meningioma because of their similar imaging characteristics. However, identifying the distinctive features of SFT on magnetic resonance imaging can distinguish it from meningioma and help to select appropriate treatment. The complete preoperative imaging data for this case indicated a highly vascularized tumor. Preoperative vascular embolization treatment reduced any difficulties during the subsequent tumor resection and minimized intraoperative bleeding.
Misplaced intraspinal venous stent causing cauda equina syndrome: illustrative case
Authors: Shah Vaibhavi , Johnstone Thomas , Haider Ghani , Marianayagam Neelan J , Stienen Martin N , Chandra Venita , Veeravagu Anand 
Published: February 2024

BACKGROUND
Endovenous stents for deep venous thrombosis treatment can be unintentionally placed in the spinal canal, resulting in neurological deficit.

OBSERVATIONS
The authors report the case of a patient presenting to our institution with intraspinal misplacement of an endovenous stent, resulting in cauda equina syndrome. The authors also performed a systematic literature review, evaluating the few previously reported cases. This review was performed according to the updated Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. In four of five cases describing stent misplacement into the spinal canal, the authors report that only anteroposterior monoplanar imaging modalities were utilized for venous localization and stent deployment. The anteroposterior plane cannot assess the relative depth of structures, nor can it distinguish between superimposed structures well. Therefore, the use of biplanar imaging should at least be considered before stent deployment, as intraspinal stent placement can lead to disastrous consequences.

LESSONS
This report should serve as an impetus for the use of biplanar or three-dimensional imaging modalities for iliac venous stent placement. Additionally, this work should increase spine surgeons’ awareness about management and operative techniques when faced with this complication.
Operative planning for a functional precision medicine assay of recurrent high-grade glioma: illustrative case
Authors: Mathews Andrew P , Shelton William J , Horta Erika Santos , Reddy Damalcheruvu Prashanth , Nix J. Stephen , Gokden Murat , Rodriguez Analiz 
Published: February 2024

BACKGROUND
Functional precision medicine (FPM) represents a personalized and efficacious modality for treating malignant neoplasms. However, acquiring sufficient live tissue to perform FPM analyses is complicated by both difficult identification on imaging and radiation necrosis, particularly in cases of recurrence. The authors describe a case of planning biopsy trajectories for an FPM assay in a patient with recurrent high-grade glioma.

OBSERVATIONS
A 25-year-old male with a history of recurrent high-grade glioma was scheduled for laser ablation and biopsy with ChemoID assaying after regions of potential recurrence were identified on follow-up imaging. Preoperative magnetic resonance (MR) spectroscopy of the regions showed areas of high choline/creatine ratios within lesions of radiation necrosis, which helped in planning the biopsy trajectories to selectively target malignancies for FPM analysis. ChemoID results showed high tumor susceptibility to lomustine, which was implemented as adjuvant therapy.

LESSONS
FPM therapy in the setting of recurrence is complicated by radiation necrosis, which can present as malignancy on imaging and interfere with tissue acquisition during biopsy or resection. Thus, operative approaches should be carefully planned with the assistance of imaging modalities such as MR spectroscopy to better ensure effective tissue acquisition for accurate FPM analysis and to promote more definitive treatment of recurrence.
Spontaneous sphenoid sinus meningocele with associated amenorrhea and headache: illustrative case
Authors: Franklin Deveney , Yamani Ali S , Boyke Andre E , Menaker Simon A , Tang Dennis , Mamelak Adam N 
Published: February 2024

BACKGROUND
Developmental meningoceles of the sphenoid sinus are uncommon. When encountered, they are often associated with cerebrospinal fluid (CSF) rhinorrhea.

OBSERVATIONS
The authors present the case of a 27-year-old female with a large meningocele eroding through the sella turcica and sphenoid sinus into the nasopharynx. The patient presented with intractable headaches and amenorrhea without CSF rhinorrhea.

LESSONS
The patient underwent an endoscopic endonasal transsphenoidal reduction of the meningocele with reelevation of the pituitary gland and skull base reconstruction with abdominal fat graft and nasoseptal flap.
The Effect of Mol of Rice Water Waste and Kepok Banana Peel to The Growth of Brassica rapa chinensis
Authors: Yuliana Meta , Dewi Belia Murni , Teristiandi Novin 
Published: February 2024

MOL merupakan larutan fermentasi oleh mikroba dan bersumber dari bahan organik seperti kulit pisang. MOL berguna dalam mendorong penguraian bahan organik dan dapat digunakan sebagai pupuk organik cair karena mengandung NPK. Penelitian ini bertujuan untuk pengaruh fermentasi campuran air cucian beras putih dan kulit pisang kepok terhadap pertumbuhan tanaman pakcoy (Brassica rapa chinensis) dan untuk mengetahui konsentrasi terbaik MOL dari kulit pisang kepok yang diberikan. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan 5 perlakuan dan 5 ulangan. Perlakuan pada penelitian ini adalah P0 (kontrol), P1 (10%), P2 (20%), P3 (30%), dan P4 (40%). Data dianalisis menggunakan analisis varians (ANOVA) yang dilanjutkan dengan Uji Duncan pada taraf signifikansi 5%. Hasil penelitian menunjukkan bahwa MOL kulit pisang kepok berpengaruh terhadap pertumbuhan tanaman pakcoy pada beberapa parameter yaitu berat basah, berat kering dan panjang akar tanaman namun tidak terhadap tinggi dan jumlah daun tanaman pakcoy. Perlakuan P2 (20%) menunjukkan hasil terbaik.
السلوك الجازم وعلاقته بمستوى الطموح لدى لاعبات كرة القدم صالات نادي فتاة اربيل الرياضي
Authors: Teacher .Dr. Bekhal is forgiving and honorable  
Published: February 2024

هدف البحث هو التعرف على العلاقة بين السلوك الجازم ومستوى الطموح لدى لاعبات كرة القدم صالات نادي فتاة اربيل الرياضي ،حيث استخدمت الباحثة المنهج الوصفي باسلوب العلاقات المتبادلة لكونه يسعى الى جمع البيانات من أفراد المجتمع ومحاولة تحديد الحالة الراهنة للمجتمع في متغيرات معينة من خلال استخدام كل من مقاييس السلوك الجازم ومستوى الطموح لدى لاعبات كرة القدم صالات نادي فتاة اربيل ، ﺘﻡ ﺍﺴﺘﺨﺩﺍﻡ المقاييس كأدوات للبحث ، واستخدمت الباحثة عدد من الوسائل الاحصائية لمعالجة النتائج التي حصلت عليها مثل الوسط الحسابي والانحراف المعياري ومعامل الارتباط البسيط (بيرسون). وتم إختيار عينة البحث من مجتمع البحث المكون من لاعبات كرة القدم للصالات والبالغ عددهن ( 20 ) لاعبة ،وبعد عرض النتائج ومناقشتها توصلت الباحثة الى وجود علاقة معنوية طردية قوية بين السوك الجازم ومستوى الطموح الرياضي للاعبات كرة القدم صالات نادي أربيل . وفي ضوء ما تم التوصل إليه من الإستنتاجات الإستفادة وضرورة الاهتمام بالنساء في كل جوانب الحياة وفي جميع الالعاب ، وخاصة الجانب النفسي ، حيث اصبح إدراج أخصائي نفسي في فرق كرة القدم النسوي اكثر من ضروري . كما يجب على المدرب والادارية الاهتمام والتركيز بالجهد المبذولة من قبل اللاعبة وليس النتيجة ، والعمل على زيادة الثقة لدى لاعبة القدم في المواقف التنافسية والتدريبية .وإجراء دراسات لوضع برامج تدريبية لتعزيز السلوك الجازم في مختلف الرياضات التنافسية .وتنمية سمة مستوى الطموح لدى اللاعبات مما يتفق مع الواقع الرياضي والاجتماعي بما يخدم نجاحاتهم المستقبلية والعمل على الحيلولة دون وقوعهم في اليأس والإحباط .
Perlindungan Terhadap Pengetahuan Tradisional Makanan Khas “Gulai Ikan Mungkus” Sebagai Kekayaan Intelektual Komunal Kabupaten Kaur
Authors: Winata Nugraha Pandu , Susetyanto Joko , Ganefi  , Hamdani  
Published: February 2024

Tujuan penelitian ini adalah untuk mengetahui : 1). Bagaimana bentuk upaya perlindungan Pengetahuan Tradisional makanan khas Gulai Ikan Mungkus yang dilakukan oleh pemerintah Daerah Kabupaten Kaur, Pelaku usaha rumah Makan tradisional Kabupaten Kaur dan Masyarakat Kabupaten Kaur, dan 2). Bagaimana Peran Pemerintah Kabupaten Kaur Untuk Melakukan Pendaftaran Makanan Khas Gulai Ikan Mungkus Sebagai Pengetahuan Tradisional Kabupaten Kaur, Penelitian ini merupakan penelitian hukum empiris, dengan menggunakan pendekatan yuridis sosiologis. Pengumpulan Data dilakukan dengan wawancara kepada respoden / sample yang terpilih, observasi, dan studi dokumen. Pengolahan data dimulai dari coding dan dan dilanjutkan dengan editing data. Setelah semua data yang relevan lengkap dan tidak ada kesalahan, dilanjutkan dengan analisis data dengan menggunakan analisis kualitatif. Untuk selanjutnya dideskripsikan dalam rangka menjawab tujuan penelitian. Hasil penelitian menunjukkan bahwa : 1). bentuk upaya perlindungan Pengetahuan Tradisional makanan khas Gulai Ikan Mungkus yang dilakukan oleh Pemerintah Daerah Kabupaten Kaur adalah dengan cara : melakukan pendataan para pelaku rumah makan yang menjual makanan khas Gulai Ikan Mungkus untuk selanjutnya diikut sertakan dalam acara festival yang diadakan oleh Pemerintah Kabupaten Kaur, menghimbau kepada semua elemen masyarakat untuk melakukan pendaftaran makanan khas Gulai Ikan Mungkus ke Dinas Pendidikan dan Kebudayaan, pembudidayaan ikan Mungkus, serta memperkenalkan makanan khas Gulai Ikan Mungkus ini kepada wisatawan luar yang datang berkunjung ke Kabupaten Kaur. Bentuk upaya perlindungan pelaku usaha rumah makan tradisional dengan tetap menjaga nilai luhur dan cita rasa makanan tradisional Gulai Ikan Mungkus, 2). Pemerintah Kabupaten Kaur belum berperan dalam melakukan pendaftaran makanan khas Gulai Ikan Mungkus.
One-step stromal vascular fraction therapy in osteoarthritis with tropoelastin-enhanced autologous stromal vascular fraction gel
Authors: Yang Junjun , Wang Xin , Zeng XueBao , Wang Rong , Ma Yanming , Fu Zhenlan , Wan Zu , Wang Zhi , Yang Liu , Chen Guangxing , Gong Xiaoyuan 
Published: February 2024

Background: Osteoarthritis (OA) is a debilitating degenerative joint disease, leading to significant pain and disability. Despite advancements, current regenerative therapies, such as mesenchymal stem cells (MSCs), face challenges in clinical efficacy and ethical considerations. This study aimed to evaluate the therapeutic potential of stromal vascular fraction gel (SVF-gel) in comparison to available treatments like hyaluronic acid (HA) and adipose-derived stem cells (ADSCs) and to assess the enhancement of this potential by incorporating tropoelastin (TE).Methods: We conducted a comparative laboratory study, establishing an indirect co-culture system using a Transwell assay to test the effects of HA, ADSCs, SVF-gel, and TE-SVF-gel on osteoarthritic articular chondrocytes (OACs). Chondrogenic and hypertrophic markers were assessed after a 72-hour co-culture. SVF-gel was harvested from rat subcutaneous abdominal adipose tissue, with its mechanical properties characterized. Cell viability was specifically analyzed for SVF-gel and TE-SVF-gel. The in vivo therapeutic effectiveness was further investigated in a rat model of OA, examining MSCs tracking, effects on cartilage matrix synthesis, osteophyte formation, and muscle weight changes.Results: Cell viability assays revealed that TE-SVF-gel maintained higher cell survival rates than SVF-gel. In comparison to the control, HA, and ADSCs groups, SVF-gel and TE-SVF-gel significantly upregulated the expression of chondrogenic markers COL 2, SOX-9, and ACAN and downregulated the hypertrophic marker COL 10 in OACs. The TE-SVF-gel showed further improved expression of chondrogenic markers and a greater decrease in COL 10 expression compared to SVF-gel alone. Notably, the TE-SVF-gel treated group in the in vivo OA model exhibited the most MSCs on the synovial surface, superior cartilage matrix synthesis, increased COL 2 expression, and better muscle weight recovery, despite the presence of fewer stem cells than other treatments.Discussion: The findings suggest that SVF-gel, particularly when combined with TE, provides a more effective regenerative treatment for OA by enhancing the therapeutic potential of MSCs. This combination could represent an innovative strategy that overcomes limitations of current therapies, offering a new avenue for patient treatment. Further research is warranted to explore the long-term benefits and potential clinical applications of this combined approach.