bluuebunny/crossref_metadata_2025_split huggingface dataset:
Translating Emirati literature: exploring culture-specific items in Mohammed Al Murr’s Dubai Tales
Authors: Al Tenaijy Moza , Al-Batineh Mohammed 
Published: January 2024

AbstractThis study investigates the translation of Emirati culture-specific items (CSIs) into English, a rarely discussed topic in Arabic translation studies. It focuses on a collection of short stories, Dubai Tales, authored by renowned Emirati author Mohammed Al Murr and translated into English by Peter Clark. The short stories vividly portray Emirati daily life, relationships and cultural values, making it an ideal set of data for a case study of translation strategies. With the emergence of the United Arab Emirates as a global multicultural hub, the demand for effective translations of Emirati literature, including CSIs, is growing. Translating effectively will not only ensure linguistic accessibility but also facilitate better worldwide communication of the unique cultural nuances woven into Emirati narratives. The study conducts quantitative and qualitative analyses of Clark’s English translation by drawing on Newmark’s (1988) cultural categories and Davies’s (2003) framework for translation strategies. The analysis revealed that Clark used globalisation, a domestication strategy, to translate most CSIs into English as well as preservation, a foreignisation strategy, to infuse exotic texture. This strategy reflected a careful balancing act aimed at reaching a wide audience while maintaining cultural elements. This study thus offers invaluable insights highlighting the dynamic relationship between culture and language in literary translations, with a special focus on the Emirati context.
Spatially-indirect and hybrid exciton–exciton interaction in MoS2 homobilayers
Authors: Maslova Valeria A , Voronova Nina S 
Published: January 2024

Abstract
Interlayer excitons in transition-metal dichalcogenide (TMD) bilayers, alongside their interplay with direct excitonic species, are supposed to offer a pathway towards robust nonlinearity, enabling the exploration of many-body quantum effects. We present a theoretical investigation of interaction among various exciton species within these structures where Coulomb attraction and repulsion are subject to reduced screening. For a homobilayer MoS2, we examine both direct, spatially-indirect, and hybridised excitons, considering the effects of direct and exchange interaction of electrons and holes distributed across one or different layers. Similar physics arises in perfectly aligned twisted TMD heterobilayers which support the direct-to-indirect exciton hybridisation. Deriving the exciton–exciton interaction matrix elements, we unveil a distinct non-monotonic dependence of the interaction on transferred momentum, changing sign from repulsive to attractive even for ground-state excitons, and compare our results with existing calculations for monolayers. Our findings demonstrate that for large momenta involved in high-density effects (strongly correlated phases), the interaction is chiefly governed by the prevailing attractive exchange component. At the same time, at small momenta that are more relevant for rarefied systems, we find that the enhancement of the interaction constant for dipolar species compared to intralayer non-dipolar excitons may be hindered by the surrounding medium. We draw comparisons with existing experiments and discuss the implications of our findings on the collective effects in TMD-based systems of excitons and exciton-polaritons.
Surface roughness of pigmented and non-pigmented maxillofacial silicone elastomer before and after artificial aging
Authors: Abdalqadir Mohammed , Saeed Znar , Azhdar Bruska 
Published: January 2024

Abstract
Maxillofacial prostheses are frequently made from silicone elastomer. The silicone material’s rough surface can lead to the accumulation of microorganisms, irritation of the surrounding soft tissue, and the progression of some microsites into mechanical failure and color deterioration. This in vitro study aimed to compare the surface roughness of M511 heat-vulcanized maxillofacial silicone before and after artificial aging. Eighty disk-shaped specimens were prepared and divided equally among five experimental groups based on pigmentation, with 16 samples in each group. The colorless specimens were prepared without adding any pigment. The four study groups were prepared using distinct pigments (red, blue, yellow, and their mixture). Half of the specimens in each group were tested before aging, while the other half was tested after 750 h of artificial aging. Surface roughness was measured using atomic force microscopy (AFM), and the silicone bonds and pigments were observed using Fourier transform infrared spectroscopy-attenuated total reflectance (FTIR-ATR). Data were compared between groups using a two-way analysis of variance, independent sample t-test, and Tukey’s post hoc test, considering a p < 0.05 statistically significant. FTIR-ATR showed no differences between the pre-and post-aging groups, with similar peaks observed. The surface roughness significantly increased in the colorless, blue, and mixed pigment groups (p < 0.001), surface roughness increased by 155.66%, 14.83%, and 96.12% respectively for colorless, blue pigment, and the mixture of pigments after 750 h of artificial aging. In contrast, the surface roughness significantly decreased in the yellow pigment (90.98%) and red pigment (5.7%) (p ≤ 0.001) after aging. The yellow pigment showed the smoothest surface after aging, while colorless specimens showed the roughest surface. Two-way ANOVA showed that pigment type and aging time significantly affected surface roughness. Therefore, induced aging considerably impacted the surface topography of maxillofacial silicone. The pigment type and distribution in the silicone matrix affected its surface roughness. The AFM analysis is a simple and straightforward method for assessing surface roughness at the nanometer level.
Selective oxidation of metallic contacts for localized chemical vapor deposition growth of 2D-transition metal dichalcogenides
Authors: Bizhani M , Jensen G , Poston W , Aldosari N , Tariq M , Aleithan S , Stinaff E 
Published: January 2024

Abstract
Chemical vapor deposition (CVD) is the most common fabrication method for transition metal dichalcogenides (TMDs) where direct chemical vapor phase reaction between an oxide transition metal and chalcogen powder results in formation of high-quality crystals of TMDs. However, in this method the nucleation is often random with incomplete nucleation and non-uniform thickness. In this work we studied the formation of a localized transition metal oxide which resulted in controllable growth of mono- to few-layer MoS2 around the formed oxide region. Bulk molybdenum patterns were irradiated with a 532 nm continuous wave laser creating a localized hot-spot which, under ambient conditions, resulted in the formation of molybdenum oxide. The characteristics of the subsequent MoS2 growth depended on the type and thickness of the MoOx which was determined by the power and duration of laser exposure. The resulting MoOx and MoS2 growth around the localized oxide regions were investigated by Raman and photoluminescence spectroscopy. Our studies have shown that exposing bulk molybdenum patterns to 10 mW of laser power for about 2s results in the minimal formation of MoO2 which coincides with high quality mono- to few-layer MoS2 growth.
Evolution of REperfusion Strategies and impact on mortality in Old and Very OLD STEMI patients. The RESOVOLD-e-MUST study
Authors: Lapostolle Frédéric , Petrovic Tomislav , Moiteaux Brice , Loyeau Aurélie , Boche Thévy , Kadji Kalabang Roger , Le Bail Gaëlle , Lamhaut Lionel , Lafay Marina , Dupas François , Scannavino Marine , Benamer Hakim , Bataille Sophie , Lambert Yves 
Published: January 2024

Abstract

Background
The use of myocardial reperfusion—mainly via angioplasty—has increased in our region to over 95%. We wondered whether old and very old patients have benefited from this development.

Methods
Setting: Greater Paris Area (Ile-de-France).

Data
Regional registry, prospective, including since 2003, data from 39 mobile intensive care units performing prehospital treatment of patients with ST segment elevation myocardial infarction (STEMI) (&lt;24 h).

Parameters
Demographic, decision to perform reperfusion and outcome (in-hospital mortality).

Primary endpoint
Reperfusion decision rate by decade over age 70.

Secondary endpoint
Outcome.

Results
We analysed the prehospital management of 27,294 patients. There were 21,311 (78%) men and 5,919 (22%) women with a median age of 61 (52–73 years). Among these patients, 8,138 (30%) were &gt; 70 years, 3,784 (14%) &gt; 80 years and 672 (2%) &gt; 90 years.
The reperfusion decision rate was 94%. It decreased significantly with age: 93, 90 and 76% in patients in their seventh, eighth and ninth decade, respectively. The reperfusion decision rate increased significantly over time. It increased in all age groups, especially the higher ones. Mortality was 6%. It increased significantly with age: 8, 16 and 25% in patients in their seventh, eighth and ninth decade, respectively. It significantly decreased over time in all age groups. The odds ratio of the impact of reperfusion decision on mortality reached 0.42 (0.26–0.68) in patients over 90 years.

Conclusion
the increase in the reperfusion decision rate was the greatest in the oldest patients. It reduced mortality even in patients over 90 years of age.
O07 CHILD syndrome and ILVEN: disorders on the same spectrum?
Authors: Paudel Pratima , Salimi Maryam , Igbokwe Rebecca , Taibjee Saleem , Ogboli Malobi , Moss Celia , Ibbs Samantha 
Published: January 2024

Abstract
Congenital Hemidysplasia with Ichthyosiform Erythroderma and Limb Defects (CHILD syndrome) is a rare X-linked dominant disorder caused by hemizygous variants in the NSDHL gene. Typically, affected girls are born with unilateral skin lesions in a Blaschkoid distribution due to random X-inactivation, and ipsilateral limb reductions. We report a genetically confirmed case without significant limb reductions and consider the relationship of CHILD syndrome to inflammatory linear verrucous epidermal naevus (ILVEN) also sometimes caused by mosaic variants in NSDHL.
A 9-month-old girl presented with extensive congenital red, scaly lesions in a Blaschkoid distribution confined to the right side of her body. Examination was otherwise normal apart from sensorineural deafness in the right ear and overlapping right 4th and 5th toes. Histology showed the characteristic foamy histiocytes of CHILD syndrome and genetic testing revealed a heterozygous pathogenic variant of NSDHL, c.262C&gt;T p.(Arg88*) previously reported in CHILD syndrome.
Patients clinically diagnosed with ILVEN but with NSDHL mutations have sometimes been reclassified as CHILD syndrome (König A et al. ILVEN encompasses a spectrum of inflammatory mosaic disorders. Am. J.Med.Genet. 2000;90:339-46). The histology of ILVEN is less specific than CHILD syndrome, without the characteristic foamy histiocytes. Nonetheless these conditions could be on a spectrum, with limb defects arising if mutant skin cells overlie the primitive limb bud (Moss C, Burn J. Hypothesis: CHILD+ILVEN=PEN or PENCIL J.Med.Genet. 1990;27:390-391).
NSDHL controls cholesterol synthesis and the topical treatment with statins plus cholesterol effective in CHILD syndrome could be considered in some cases of ILVEN.
O09 Targeted genetic therapy for congenital melanocytic naevi
Authors: Bryant Dale , Barberan-Martin Sara , Maeshima Ruhina , Del Valle Torres Ignacio , Rabii Mohammad , Sauvadet Aimie , Demetriou Charalambos , Knöpfel Nicole , Michailides Fanis , Riachi Melissa , Zecchin Davide , Pittman Alan , Polubothu Satyamaanasa , Hart Steve , Kinsler Veronica 
Published: January 2024

Abstract
Severe cases of congenital melanocytic naevi (CMN) are associated with substantial cutaneous and neurological morbidity and an excess childhood mortality from melanoma. Effective treatments are lacking. This mosaic disorder is caused most commonly by a heterozygous oncogenic variant NRAS c.181C&gt;A, p.(Q61K). As NRAS has multiple downstream effectors we have sought to treat this disease by precision genetic therapy rather than downstream pathway inhibition, hypothesising that silencing of the oncogenic allele may remove cellular protection from RAS induced apoptosis. Using a lead siRNA selected for allele specificity and fewest off-target effects on RNAseq (siNRASQ61K) we show here significant selective knockdown of variant mRNA expression and knockdown of NRAS protein levels. A single treatment to primary naevus cell cultures leads to normalisation of MAPK pathway activation, reduction in proliferation rate, and importantly, triggering of apoptosis. We go on to demonstrate that receptor-targeted lipid nanoparticles (RTNPs) successfully protect siRNA from degradation, deliver cargo to naevus cells in patient skin explants and improve naevus cell targeting. A single intradermal injection of siNRASQ61K-RTNPs into transgenic mice harbouring humanised NRASQ61K(Tyr::NRASQ61K) confirms significant selective knockdown of the variant NRAS allele in vivo.Successful targeting of variant NRAS and triggering of naevus cell apoptosis now paves the way for clinical trials of this genetic therapy for CMN.
P18 Giant Periocular Juvenile Xanthogranulomas Treated with Trametinib
Authors: Poudel Pratima , Millen Gerard , Ogboli Malobi 
Published: January 2024

Abstract
Juvenile Xanthogranuloma (JXG), the commonest type of non-Langerhans cell histiocytosis, is regarded as a benign self-limiting condition of infancy, characterised by asymptomatic yellow brown papulonodular lesions, usually confined to the skin but occasionally affecting the eyes or internal organs. Skin lesions characteristically regress spontaneously within 3-6 years. We describe an unusually aggressive cutaneous presentation requiring input from paediatric oncology.
A 6 year old boy presented with extensive soft yellowish papules, plaques and nodules particularly around the eyes but also over the chest and leg. Biopsy confirmed the clinical diagnosis of JXG. The lesions enlarged progressively with new lesions appearing, causing significant distortion of the upper and lower eyelids with reduced ability to open the eyes, discomfort and distress.
Treatment was started with topical steroids, progressing to intralesional and systemic steroids, but with minimal effect. In view of the severity, vinblastine and subsequently cytarabine were added, again with limited benefit. The periocular lesions were surgically debulked and he was commenced on Trametinib (a MEK inhibitor) with a good response. Now aged 9 years, and the patient displayed a favourable clinical response after 3 months of being on Trametinib.
JXG rarely requires treatment, but there is no recognised therapy for the occasional problematic lesions. In this case trametinib was effective and well-tolerated. The efficacy of trametinib in histiocytosis has been attributed to the presence of activating BRAF and MAP2K1 mutations. Genetic analysis of JXG may guide future therapies.
Five paediatric patients with mycosis fungoides and our approach to provide age-appropriate information and psychological support
Authors: Melchionda Veronica , Ieremia Eleni , Matin Rubeta , McPherson Tess 
Published: January 2024

Abstract
Cutaneous lymphoproliferative diseases in childhood are rare and they are clinically and pathologically heterogeneous, which makes their diagnosis challenging. Although there is limited long-term data and guidance on management, evidence suggests these to be different conditions from cutaneous lymphoma in adults, highlighting the need for age-appropriate patient information. We present clinical outcomes for our paediatric cohort of five patients with mycosis fungoides, emphasizing that despite diagnostic delays, mycosis fungoides in this age group tends to yield a good prognosis. It remains uncommon to provide clinical expertise together with psychological support in a dermatology paediatric service. Here, we provide our experience in offering this combined service. In conjunction with these patients, we have co-produced an accessible patient information leaflet targeted at a younger audience for support and to clarify potential misconceptions from a diagnosis of cutaneous lymphoma.
Evaluation of the 2023 Duke-ISCVID and 2023 Duke-ESC Clinical Criteria for the Diagnosis of Infective Endocarditis in a Multicenter Cohort of Patients With Staphylococcus aureus Bacteremia
Authors: Papadimitriou-Olivgeris Matthaios , Monney Pierre , Frank Michelle , Tzimas Georgios , Tozzi Piergiorgio , Kirsch Matthias , Van Hemelrijck Mathias , Bauernschmitt Robert , Epprecht Jana , Guery Benoit , Hasse Barbara 
Published: January 2024

Abstract

Background
The Duke criteria for infective endocarditis (IE) diagnosis underwent revisions in 2023 by the European Society of Cardiology (ESC) and the International Society for Cardiovascular Infectious Diseases (ISCVID). This study aims to assess the diagnostic accuracy of these criteria, focusing on patients with Staphylococcus aureus bacteremia (SAB).

Methods
This Swiss multicenter study conducted between 2014 and 2023 pooled data from three cohorts. It evaluated the performance of each iteration of the Duke criteria by assessing the degree of concordance between definite S. aureus IE (SAIE) and the diagnoses made by the Endocarditis Team (2018–23) or IE expert clinicians (2014–17).

Results
Among 1344 SAB episodes analyzed, 486 (36%) were identified as cases of SAIE. The 2023 Duke-ISCVID and 2023 Duke-ESC criteria demonstrated improved sensitivity for SAIE diagnosis (81% and 82%, respectively) compared to the 2015 Duke-ESC criteria (75%). However, the new criteria exhibited reduced specificity for SAIE (96% for both) compared to the 2015 criteria (99%). Spondylodiscitis was more prevalent among patients with SAIE compared to those with SAB alone (10% vs 7%, P = .026). However, when patients meeting the minor 2015 Duke-ESC vascular criterion were excluded, the incidence of spondylodiscitis was similar between SAIE and SAB patients (6% vs 5%, P = .461).

Conclusions
The 2023 Duke-ISCVID and 2023 Duke-ESC clinical criteria show improved sensitivity for SAIE diagnosis compared to 2015 Duke-ESC criteria. However, this increase in sensitivity comes at the expense of reduced specificity. Future research should aim at evaluating the impact of each component introduced within these criteria.
Deaf patients’ preferred communication in clinical settings: implications for healthcare providers
Authors: Hall Sarah , Ballard Michael 
Published: December 2023

Abstract
Deaf patients who communicate in American Sign Language (ASL) experience communication challenges leading to medical errors, treatment delays, and health disparities. Research on Deaf patient communication preferences is sparse. Researchers conducted focus groups based on the Health Belief Model with culturally Deaf patients and interpreters. The ASL focus groups were interpreted and transcribed into written English, verified by a third-party interpreting agency, and uploaded into NVivo. Deductive coding was used to identify communication methods and inductive coding was used to identify themes within each. Writing back-and-forth introduced challenges related to English proficiency, medical terminology, poor penmanship, and tendencies of providers to abbreviate. Participants had various speechreading abilities and described challenges with mask mandates. Multiple issues were identified with family and friends as proxy interpreters, including a lack of training, confidentiality issues, emotional support, and patient autonomy. Video remote interpreter challenges included technical, environmental, and interpreter qualification concerns. Participants overwhelmingly preferred on-site interpreters for communication clarity. While there was a preference for direct care, many acknowledged this is not always feasible due to lack of providers fluent in ASL. Access to on-site interpreters is vital for many Deaf patients to provide full access to critical medical information. Budget allocation for on-call interpreters is important in emergency settings.
Methionol as an aggregation-sex pheromone of the desert-dwelling beetleEustromula valida(Coleoptera: Cerambycidae)
Authors: Halloran Sean , Zou Yunfan , Arriola Kyle , Roepke René , Hanks Lawrence M , Millar Jocelyn G 
Published: December 2023

AbstractAs part of a long-term project on unraveling the use of pheromones in the large beetle family Cerambycidae, field trials were conducted with generic blends of known cerambycid pheromones at a desert site in southern California. In the first year of testing (2022), the species Eustromula valida (LeConte) (subfamily Cerambycinae, tribe Elaphidiini) and Aethecerinus latecinctus (Horn) (Cerambycinae, Trachyderini) were weakly attracted to one of the lure blends. In follow-up trials in 2023, only E. valida were caught, and collection of volatiles from both sexes of E. valida determined that males sex-specifically produced 3-methylthiopropan-1-ol (methionol), a compound that was not in the tested lure blends. Beetles of both sexes were strongly and specifically attracted to this compound in field bioassays, verifying that it is an aggregation-sex pheromone. No sympatric species were attracted to methionol while it was deployed in the field. Several recent studies have identified methionol as a pheromone component for other cerambycid species in both North and South America, suggesting it may represent another common pheromone component within the Cerambycidae.
Sex differences in the nutritional status and its association with long-term prognosis in patients with heart failure with reduced ejection fraction: a prospective cohort study
Authors: Kałużna-Oleksy Marta , Krysztofiak Helena , Sawczak Filip , Kukfisz Agata , Szczechla Magdalena , Soloch Aleksandra , Cierzniak Maria , Szubarga Alicja , Przytarska Katarzyna , Dudek Magdalena , Uchmanowicz Izabella , Straburzyńska-Migaj Ewa 
Published: January 2024

Abstract

Aims
Many studies show the association between malnutrition and poor prognosis in heart failure (HF) patients. Our research aimed to analyse sex differences in patients with HF with reduced ejection fraction (HFrEF), emphasizing nutritional status and the influence of selected parameters on the prognosis.

Methods and results
We enrolled 276 consecutive patients diagnosed with HFrEF. Nutritional status was assessed using Mini Nutritional Assessment (MNA), geriatric nutritional risk index (GNRI), and body mass index (BMI). The mean follow-up period was 564.4 ± 346.3 days. The analysed group included 81.2% of men. The median age was 58, interquartile range (IQR) 49–64 years. Among all patients, almost 60% were classified as NYHA III or IV. Half of the participants were at risk of malnutrition, and 2.9% were malnourished. During follow-up, 72 (26.1%) patients died. The female sex was not associated with a higher occurrence of malnutrition (P = 0.99) or nutritional risk (P = 0.85), according to MNA. Coherently, GNRI scores did not differ significantly between the sexes (P = 0.29). In contrast, BMI was significantly higher in males (29.4 ± 5.3 vs. 25.9 ± 4.7; P &lt; 0.001). Impaired nutritional status assessed with any method (MNA, GNRI, BMI) was not significantly associated with a worse prognosis. In multivariable analysis, NYHA class, lower estimated glomerular filtration rate, higher B-type natriuretic peptide (BNP), higher N-terminal fragment of proBNP, and higher uric acid were independent of sex and age predictors of all-cause mortality.

Conclusion
There were no sex differences in the nutritional status in the HFrEF patients, apart from lower BMI in females. Impaired nutritional status was not associated with mortality in both men and women.