bluuebunny/crossref_metadata_2025_split huggingface dataset:
Asymptotics for the infinite Brownian loop on noncompact symmetric spaces
Authors: Papageorgiou Effie 
Published: October 2023

AbstractThe infinite Brownian loop on a Riemannian manifold is the limit in distribution of the Brownian bridge of length T around a fixed origin when $$T \rightarrow +\infty $$

T
→
+
∞

. The aim of this note is to study its long-time asymptotics on Riemannian symmetric spaces G/K of noncompact type and of general rank. This amounts to the behavior of solutions to the heat equation subject to the Doob transform induced by the ground spherical function. Unlike the standard Brownian motion, we observe in this case phenomena which are similar to the Euclidean setting, namely $$L^1$$

L
1

asymptotic convergence without requiring bi-K-invariance for initial data, and strong $$L^{\infty }$$

L
∞

convergence.
A Brief History of the History of Capitalism, and a New American Variety
Authors: Schakenbach Regele Lindsay 
Published: October 2023

Since the new history of capitalism (NHOC) trend received national publicity in 2013, American historians have enthusiastically pursued the complexities and varieties of capitalism, producing a body of scholarship that offers a plethora of capitalism-modifying adjectives yet leaves capitalism undefined. “A Brief History of the History of Capitalism, and a New American Variety” asks how historians developed these varieties and interpretations, and whether any gaps or limitations remain. To answer these questions, the essay begins with a survey of the many histories of capitalism, from the first use of the term, to America’s first business histories in the early twentieth century, to world systems theory, and up to the NHOC. It then makes the case for continued attempts at redefinition and specification by offering a new variety.This new variety, martial capitalism, has its roots in the early national and antebellum eras and influenced the evolution of capitalism in the United States. It is a system of political economy in which concealed military power, rather than abstract market forces, serves as an invisible (“invisible,” at least, to those not subjected to it) hand and bestows economic opportunity upon some individuals. Under this system, government officials and private citizens coercively acquired resources, knowledge, territory, and “free trade” agreements in the service of aggressive economic opportunism. Steady military conflict, along with scattered and localized violence, intersected with honor, a mainstay in early American politics and culture, to engender a set of masculinized economic relations that shaped both the what/where and the how of capitalism in the United States.
Comparative antimicrobial use in coronavirus disease 2019 (COVID-19) and non–COVID-19 inpatients from 2019 to 2020: A multicenter ecological study
Authors: Santos Carlos A.Q. , Tseng Marion , Martinez Ashley I. , Shankaran Shivanjali , Hodgson Hayley A. , Ahmad Faraz S. , Zhang Huiyuan , Sievert Dawn M. , Trick William E. 
Published: October 2023

AbstractObjective:We sought to determine whether increased antimicrobial use (AU) at the onset of the coronavirus disease 2019 (COVID-19) pandemic was driven by greater AU in COVID-19 patients only, or whether AU also increased in non–COVID-19 patients.Design:In this retrospective observational ecological study from 2019 to 2020, we stratified inpatients by COVID-19 status and determined relative percentage differences in median monthly AU in COVID-19 patients versus non–COVID-19 patients during the COVID-19 period (March–December 2020) and the pre–COVID-19 period (March–December 2019). We also determined relative percentage differences in median monthly AU in non–COVID-19 patients during the COVID-19 period versus the pre–COVID-19 period. Statistical significance was assessed using Wilcoxon signed-rank tests.Setting:The study was conducted in 3 acute-care hospitals in Chicago, Illinois.Patients:Hospitalized patients.Results:Facility-wide AU for broad-spectrum antibacterial agents predominantly used for hospital-onset infections was significantly greater in COVID-19 patients versus non–COVID-19 patients during the COVID-19 period (with relative increases of 73%, 66%, and 91% for hospitals A, B, and C, respectively), and during the pre–COVID-19 period (with relative increases of 52%, 64%, and 66% for hospitals A, B, and C, respectively). In contrast, facility-wide AU for all antibacterial agents was significantly lower in non–COVID-19 patients during the COVID-19 period versus the pre–COVID-19 period (with relative decreases of 8%, 7%, and 8% in hospitals A, B, and C, respectively).Conclusions:AU for broad-spectrum antimicrobials was greater in COVID-19 patients compared to non–COVID-19 patients at the onset of the pandemic. AU for all antibacterial agents in non–COVID-19 patients decreased in the COVID-19 period compared to the pre–COVID-19 period.
Regulating free speech in a democracy: Lysias 10Against Theomnestosand the law on slander
Authors: Livingstone Niall 
Published: October 2023

AbstractLysias 10Against Theomnestosis the only surviving example of a classical Greek speech on a charge of slander (dikē kakēgorias). The case turns on establishing communal consensus in evaluation of meta-discursive claims: assertions as to what the law says about what citizens can say about their fellow citizens. I adapt Marmor’s account of the pragmatics of legal discourse to illuminate the litigants’ strategies as they seek to control interpretation of the legal question in this much-discussed case from 380s BC Athens. We see how each party used different assumptions about the law’s implicatures as well as its declarative meaning and presented these assumptions as grounded in common sense. The persuasive methods used by Lysias’ client are illuminated by means of cognitive narratology’s application of Lewisian possible-world logic to the creation of story-worlds and the relationships they generate between narrator and reader/audience. So understood, Lysias’ speech helps answer questions about the role and limits of free/frank speech (parrhēsia) in democratic Athens and about the relationship between individual agency and the collective agency of thedēmos, questions crucial to an understanding of the place of legal discourse and legal conflict in the ideology and day-to-day praxis of the democratic city.
Application of Telemedicine in the Ambulance for Stroke Patients: A Systematic Review
Authors: Sarpourian Fatemeh , Ahmadi Marzaleh Milad , Fatemi Aghda Seyed Ali , Zare Zahra 
Published: October 2023

AbstractIntroduction:The use of telemedicine for the prehospital management of emergency conditions, especially stroke, is increasing day by day. Few studies have investigated the applications of telemedicine in Emergency Medical Services (EMS). A comprehensive study of the applications of this technology in stroke patients in ambulances can help to build a better understanding. Therefore, this systematic review was conducted to investigate the use of telemedicine in ambulances for stroke patients in 2023.Methods:A systematic search was conducted in PubMed, Cochrane, Scopus, ProQuest, Science Direct, and Web of Science from 2013 through March 1, 2023. The authors selected the articles based on keywords and criteria and reviewed them in terms of title, abstract, and full text. Finally, the articles that were related to the study aim were evaluated.Results:The initial search resulted in the extraction of 2,795 articles. After review of the articles, and applying the inclusion and exclusion criteria, seven articles were selected for the final analysis. Three (42.85%) studies were on the feasibility and intervention types. Also, randomized trials, feasibility, feasibility and prospective-observational, and feasibility and retrospective-interventional studies were each one (14.28%). Six (85.71%) of the studies were conducted in the United States. The National Institutes of Health Stroke Scale (NIHSS) and RP-Xpress were the most commonly used tools for neurological evaluations and teleconsultations.Conclusion:Remote prehospital consultations, triage, and sending patient data before they go to the emergency department can be provided through telemedicine in ambulances. Neurological evaluations via telemedicine are reliable and accurate, and they are almost equal to in-person evaluations by a neurologist.
9-1-1 Activations from Ambulatory Care Centers: A Sicker Pediatric Population
Authors: Heyming Theodore W. , Knudsen-Robbins Chloe , Shelton Shelby K. , Pham Phung K. , Brukman Shelley , Wickens Maxwell , Valdez Brooke , Bacon Kellie , Thorpe Jonathan , Kwon Kenneth T. , Schultz Carl 
Published: October 2023

AbstractBackground:Pediatric patients transferred by Emergency Medical Services (EMS) from urgent care (UC) and office-based physician practices to the emergency department (ED) following activation of the 9-1-1 EMS system are an under-studied population with scarce literature regarding outcomes for these children. The objectives of this study were to describe this population, explore EMS level-of-care transport decisions, and examine ED outcomes.Methods:This was a retrospective review of patients zero to <15 years of age transported by EMS from UC and office-based physician practices to the ED of two pediatric receiving centers from January 2017 through December 2019. Variables included reason for transfer, level of transport, EMS interventions and medications, ED medications/labs/imaging ordered in the first hour, ED procedures, ED disposition, and demographics. Data were analyzed with descriptive statistics, X2 test, point biserial correlation, two-sample z test, Mann-Whitney U test, and 2-way ANOVA.Results:A total of 450 EMS transports were included in this study: 382 Advanced Life Support (ALS) runs and 68 Basic Life Support (BLS) runs. The median patient age was 2.66 years, 60.9% were male, and 60.7% had private insurance. Overall, 48.9% of patients were transported from an office-based physician practice and 25.1% were transported from UC. Almost one-half (48.7%) of ALS patients received an EMS intervention or medication, as did 4.41% of BLS patients. Respiratory distress was the most common reason for transport (46.9%). Supplemental oxygen was the most common EMS intervention and albuterol was the most administered EMS medication. There was no significant association between level of transport and ED disposition (P = .23). The in-patient admission rate for transported patients was significantly higher than the general ED admission rate (P <.001).Conclusion:This study demonstrates that pediatric patients transferred via EMS after activation of the 9-1-1 system from UC and medical offices are more acutely ill than the general pediatric ED population and are likely sicker than the general pediatric EMS population. Paramedics appear to be making appropriate level-of-care transport decisions.
Feasibility, acceptability and clinical benefit of a trauma-focused stabilisation group for post-traumatic stress disorder patients with complex presentations on primary care waitlists
Authors: Wells Michelle , Karl Anke , Handley Rachel 
Published: October 2023

AbstractBackground:Large numbers of people showing complex presentations of post-traumatic stress disorder (PTSD) in the NHS Talking Therapies services routinely require multi-faceted and extended one-to-one National Institute of Clinical Excellence (NICE) recommended treatment approaches. This can lead to longer waits for therapy and prolong patient suffering. We therefore evaluated whether a group stabilisation intervention delivered to patients on the waitlist for individual trauma-focused psychological treatment could help address this burden.Aims:The study aimed to ascertain a trauma-focused stabilisation group’s acceptability, feasibility, and preliminary clinical benefit.Method and results:Fifty-eight patients with PTSD waiting for trauma-focused individual treatment were included in the study. Two therapists delivered six 5-session groups. The stabilisation group was found to be feasible and acceptable. Overall, PTSD symptom reduction was medium to large, with a Cohen’s d of .77 for intent-to-treat and 1.05 for per protocol analyses. Additionally, for depression and anxiety, there was minimal symptom deterioration.Conclusions:The study provided preliminary evidence for the acceptability, feasibility and clinical benefit of attending a psychoeducational group therapy whilst waiting for one-to-one trauma therapy.
Timing the Hegenshan Suture in the Central Asian Orogenic Belt: New Paleomagnetic and Geochronological Constraints From Southeastern Mongolia
Authors: Ren Qiang , Zhang Shihong , Sukhbaatar Turbold , Hou Mingcai , Wu Huaichun , Yang Tianshui , Li Haiyan , Chen Anqing 
Published: October 2023

AbstractThe timing of formation of the Hegenshan suture is crucial to understanding the evolution of the Central Asian Orogenic Belt (CAOB). Here we present a well‐dated paleomagnetic pole (103 samples from 15 sites, 36.7°N/29.2°E, A95 = 3.3°) that passed a positive fold test, a reversal test, and a conglomerate test from the ∼250 Ma upper Gunbayn Formation andesites in the southeastern Mongolia Block (MOB). The high‐quality paleomagnetic database may demonstrate that the MOB drifted rapidly southward and collided with the Xilinhot–Songliao Block between 256 and 250 Ma, resulting in the closure of the Hegenshan Ocean at ∼250 Ma. The Hegenshan suture and the Solonker suture were formed almost simultaneously and marked the final closure of the Paleo‐Asian Ocean.
A novel evolutionary method for parameter-free MEMS structural design and its application in piezoresistive pressure sensors
Authors: Meng Qinggang , Wang Junbo , Chen Deyong , Chen Jian , Xie Bo , Lu Yulan 
Published: October 2023

AbstractIn this paper, a novel simulation-based evolutionary method is presented for designing parameter-free MEMS structures with maximum degrees of freedom. This novel design method enabled semiautomatic structure evolution by weighing the attributes of each segment of the structure and yielded an optimal design after multiple iterations. The proposed method was utilized to optimize the pressure-sensitive diaphragm of a piezoresistive pressure sensor (PPS). Finite element method (FEM) simulations revealed that, in comparison to conventional diaphragms without islands and with square islands, the optimized diaphragm increased the stress by 10% and 16% and reduced the nonlinearity by 57% and 77%, respectively. These improvements demonstrate the value of this method. Characterization of the fabricated PPS revealed a high sensitivity of 8.8 mV V−1 MPa−1 and a low nonlinearity of 0.058% FS at 20 °C, indicating excellent sensor performance.
Decoding the metastatic potential and optimal postoperative adjuvant therapy of melanoma based on metastasis score
Authors: Shen Kangjie , Song Wenyu , Wang Hongye , Wang Lu , Yang Yang , Hu Qianrong , Ren Min , Gao Zixu , Wang Qiangcheng , Zheng Shaoluan , Zhu Ming , Yang Yanwen , Zhang Yong , Wei Chuanyuan , Gu Jianying 
Published: October 2023

AbstractMetastasis is a formidable challenge in the prognosis of melanoma. Accurately predicting the metastatic potential of non-metastatic melanoma (NMM) and determining effective postoperative adjuvant treatments for inhibiting metastasis remain uncertain. In this study, we conducted comprehensive analyses of melanoma metastases using bulk and single-cell RNA sequencing data, enabling the construction of a metastasis score (MET score) through diverse machine-learning algorithms. The reliability and robustness of the MET score were validated using various in vitro assays and in vivo models. Our findings revealed a distinct molecular landscape in metastatic melanoma characterized by the enrichment of metastasis-related pathways, intricate cell–cell communication, and heightened infiltration of pro-angiogenic tumor-associated macrophages compared to NMM. Importantly, patients in the high MET score group exhibited poorer prognoses and an immunosuppressive microenvironment, featuring increased infiltration of regulatory T cells and decreased infiltration of CD8+ T cells, compared to the low MET score patient group. Expression of PD-1 was markedly higher in patients with low MET scores. Anti-PD-1 (aPD-1) therapy profoundly affected antitumor immunity activation and metastasis inhibition in these patients. In summary, our study demonstrates the effectiveness of the MET score in predicting melanoma metastatic potential. For patients with low MET scores, aPD-1 therapy may be a potential treatment strategy to inhibit metastasis. Patients with high MET scores may benefit from combination therapies.
The monosialoganglioside GM1a protects against complement attack
Authors: Wedekind Henri , Beimdiek Julia , Rossdam Charlotte , Kats Elina , Wittek Vanessa , Schumann Lisa , Sörensen-Zender Inga , Fenske Arno , Weinhold Birgit , Schmitt Roland , Tiede Andreas , Büttner Falk F. R. , Münster-Kühnel Anja , Abeln Markus 
Published: October 2023

AbstractThe complement system is a part of the innate immune system in the fluid phase and efficiently eliminates pathogens. However, its activation requires tight regulation on the host cell surface in order not to compromise cellular viability. Previously, we showed that loss of placental cell surface sialylation in mice in vivo leads to a maternal complement attack at the fetal-maternal interface, ultimately resulting in loss of pregnancy. To gain insight into the regulatory function of sialylation in complement activation, we here generated trophoblast stem cells (TSC) devoid of sialylation, which also revealed complement sensitivity and cell death in vitro. Glycolipid-analysis by multiplexed capillary gel electrophoresis coupled to laser-induced fluorescence detection (xCGE-LIF) allowed us to identify the monosialoganglioside GM1a as a key element of cell surface complement regulation. Exogenously administered GM1a integrated into the plasma membrane of trophoblasts, substantially increased binding of complement factor H (FH) and was sufficient to protect the cells from complement attack and cell death. GM1a treatment also rescued human endothelial cells and erythrocytes from complement attack in a concentration dependent manner. Furthermore, GM1a significantly reduced complement mediated hemolysis of erythrocytes from a patient with Paroxysmal nocturnal hemoglobinuria (PNH). This study demonstrates the complement regulatory potential of exogenously administered gangliosides and paves the way for sialoglycotherapeutics as a novel substance class for membrane-targeted complement regulators.
PADAPT 1.0 – the Pannonian Dataset of Plant Traits
Authors: Sonkoly Judit , Tóth Edina , Balogh Nóra , Balogh Lajos , Bartha Dénes , Csendesné Bata Kinga , Bátori Zoltán , Békefi Nóra , Botta-Dukát Zoltán , Bölöni János , Csecserits Anikó , Csiky János , Csontos Péter , Dancza István , Deák Balázs , Dobolyi Zoltán Konstantin , E-Vojtkó Anna , Gyulai Ferenc , Hábenczyus Alida Anna , Henn Tamás , Horváth Ferenc , Höhn Mária , Jakab Gusztáv , Kelemen András , Király Gergely , Kis Szabolcs , Kovacsics-Vári Gergely , Kun András , Lehoczky Éva , Lengyel Attila , Lhotsky Barbara , Löki Viktor , Lukács Balázs András , Matus Gábor , McIntosh-Buday Andrea , Mesterházy Attila , Miglécz Tamás , Molnár V Attila , Molnár Zsolt , Morschhauser Tamás , Papp László , Pósa Patrícia , Rédei Tamás , Schmidt Dávid , Szmorad Ferenc , Takács Attila , Tamás Júlia , Tiborcz Viktor , Tölgyesi Csaba , Tóth Katalin , Tóthmérész Béla , Valkó Orsolya , Virók Viktor , Wirth Tamás , Török Péter 
Published: October 2023

AbstractThe existing plant trait databases’ applicability is limited for studies dealing with the flora and vegetation of the eastern and central part of Europe and for large-scale comparisons across regions, mostly because their geographical data coverage is limited and they incorporate records from several different sources, often from regions with markedly different climatic conditions. These problems motivated the compilation of a regional dataset for the flora of the Pannonian region (Eastern Central Europe). PADAPT, the Pannonian Dataset of Plant Traits relies on regional data sources and collates data on 54 traits and attributes of the plant species of the Pannonian region. The current version covers approximately 90% of the species of the region and consists of 126,337 records on 2745 taxa. By including species of the eastern part of Europe not covered by other databases, PADAPT can facilitate studying the flora and vegetation of the eastern part of the continent. Although data coverage is far from complete, PADAPT meets the longstanding need for a regional database of the Pannonian flora.
How are exclusively data journals indexed in major scholarly databases? An examination of four databases
Authors: Jiao Chenyue , Li Kai , Fang Zhichao 
Published: October 2023

AbstractThe data paper is becoming a popular way for researchers to publish their research data. The growing numbers of data papers and journals hosting them have made them an important data source for understanding how research data is published and reused. One barrier to this research agenda is a lack of knowledge as to how data journals and their publications are indexed in the scholarly databases used for quantitative analysis. To address this gap, this study examines how a list of 18 exclusively data journals (i.e., journals that primarily accept data papers) are indexed in four popular scholarly databases: the Web of Science, Scopus, Dimensions, and OpenAlex. We investigate how comprehensively these databases cover the selected data journals and, in particular, how they present the document type information of data papers. We find that the coverage of data papers, as well as their document type information, is highly inconsistent across databases, which creates major challenges for future efforts to study them quantitatively, which should be addressed in the future.
LESO: A ten-year ensemble of satellite-derived intercontinental hourly surface ozone concentrations
Authors: Zhu Songyan , Xu Jian , Zeng Jingya , Yu Chao , Wang Yapeng , Wang Haolin , Shi Jiancheng 
Published: October 2023

AbstractThis study presents a novel ensemble of surface ozone (O3) generated by the LEarning Surface Ozone (LESO) framework. The aim of this study is to investigate the spatial and temporal variation of surface O3. The LESO ensemble provides unique and accurate hourly (daily/monthly/yearly as needed) O3 surface concentrations on a fine spatial resolution of 0.1◦ × 0.1◦ across China, Europe, and the United States over a period of 10 years (2012–2021). The LESO ensemble was generated by establishing the relationship between surface O3 and satellite-derived O3 total columns together with high-resolution meteorological reanalysis data. This breakthrough overcomes the challenge of retrieving O3 in the lower atmosphere from satellite signals. A comprehensive validation indicated that the LESO datasets explained approximately 80% of the hourly variability of O3, with a root mean squared error of 19.63 μg/m3. The datasets convincingly captured the diurnal cycles, weekend effects, seasonality, and interannual variability, which can be valuable for research and applications related to atmospheric and climate sciences.