bluuebunny/crossref_metadata_2025_split huggingface dataset:
CLINICAL, ANGIOGRAPHIC AND FUNCTIONAL PARAMETERS DETERMINING DECISION TO PERFORM REVASCULARIZATION IN STABLE CORONARY ARTERY DISEASE PATIENTS WITH INTERMEDIATE CORONARY LESIONS
Authors: Stan Mykola V. , Mikhaliev Кyrylo О. , Zharinov Oleg J. , Khokhlov Andriy V. , Todurov Borys M. 
Published: December 2023

The aim: to study the clinical, angiographic and functional parameters, and their relation to the decision on percutaneous coronary intervention (PCI) in stable coronary artery disease (CAD) patients with intermediate coronary stenoses (ІСS) at patient and lesion levels.
Materials and methods. The cross-sectional study enrolled 123 patients (62±9 years; 73,2 % males) with stable CAD and angiographically ICS (50-90 %). Stable angina CCS class II (CCSII) was diagnosed in 70 (56,9 %) patients, class III (CCSIII) – 29 (23,6 %); 24 (19,5 %) patients were free from angina (Afree). Fractional flow reserve (FFR) was assessed in 74 (60,2 %) patients (min per patient). The hemodynamically significant lesion was considered if FFR ≤0,80 a.u. The decision to perform PCI was undertaken in 93 (76 %) patients. In addition, the functional data from 128 lesions were analyzed.
Results. The CCSIII group was characterized by less frequent previous PCI (21 % vs. 46 % in the pooled group [CCSII + Afree]; р=0,018); the predominance of cases with (max) severe [70-90 %] coronary stenosis (96 % vs. 78 % in CCSII and 54 % in Afree; ptrend<0,001); the lower (min) FFR ([median, quartiles] 0,70 (0,64-0,74) vs. 0,87 (0,81-0,90) in Afree; p˂0,002); and the decision to perform PCI in the vast majority of cases (93 % vs. 79 % in CCSII and 46 % in Afree; ptrend<0,001). The Afree/CCSII/CCSIII groups demonstrated a trend towards a decrease in frequency of cases with (max) [60-69 %] stenosis (38 %, 13 % and none, respectively; ptrend<0,001), and a tendency towards the cases with (max) [80-90 %] stenosis to be more prevalent (29 %, 39 % and 55 %, respectively; ptrend=0,051). The frequency of cases with (max) stenosis [70-79 %] was comparable in the studied groups (Afree/CCSII/CCSIII: 25 %/39 %/41 %, respectively [ptrend=0,240]). At lesion-level, all [80-90 %] lesions (n=28) appeared to be hemodynamically significant. In turn, the [60-69 %] lesions (n=24) included 5 (21 %) significant ones. Finally, the [70-79 %] lesions (n=44) included 28 (64 %) significant and 16 (36 %) non-significant ones.
Conclusions. Among the stable CAD patients with angiographically ICS, those with CCSIII were characterized by less frequent previous PCI, significant decrease in FFR and the decision to perform index PCI in the vast majority of cases. There is a need for more precise diagnosis and assessment of myocardial ischemia in patients with an intermediate pre-test obstructive CAD probability, including the cases of previously performed PCI.
THE PERSPECTIVE OF N-CHLOROTAURINE INFLUENCE ON MULTI-DRUF RESISTANT MICROORGANISMS ASSOCIATED WITH DENTAL IMPLANTATION FAILURE
Authors: Efimenko Anastasiia O. , Ishchenko Oksana V. , Koshova Iryna P. , Murashevych Bohdan V. , Stepanskyi Dmytro O. 
Published: December 2023

Introduction: Microorganisms colonizing the surface of dental implants can form biofilms that protect their microcolonies from mechanical impact, antimicrobial compounds, and immune factors. Prophylactic use of antibiotics during dental implantation can exert selective pressure on the development of antimicrobial resistance. In this context, N-chlorotaurine (NCT) is a promising compound to combat resistant agents.
The aim is to investigate the efficacy of NCT against pathogens associated with dental implant complications.
Materials and methods. A buffered 1% NCT solution adjusted to pH 7.1 was used for the study. Multidrug-resistant cultures (MDR) were identified. Determination of NCT activity was carried out by the agar and suspension method.
The results. After standard antibiotic susceptibility testing, cultures classified as MDR were selected. 12 cultures were included in the MDR group, including seven S. aureus, three K. pneumoniae and three A. baumannii. MDR cultures of S. aureus had MRSA profile. Production of carbapenemases was confirmed in all MDR K. pneumoniae isolates, 2 of them showed production of metallo-β-lactamases. MDR isolates A. baumannii were also producers of metallo-β-lactamases. All 12 investigated MDR cultures were sensitive to NCT, the diameter of the zones of growth retardation was at least 15 mm. No significant difference was found between the effectiveness of 1% NCT solution against microorganisms with different mechanisms of drug resistance (t-test, p>0.05). When conducting studies in a liquid environment, a 1% NCT solution showed similar results, all MDR cultures were sensitive and showed a decrease in the microbial load (CFU/ml) by at least 2 log10 steps already 15 minutes after the start of the study. Notably, there was no significant difference in the efficacy of NCT against conditionally susceptible and MDR agents.
Conclusions. Reducing the threat and burden of MDR pathogens is one of the goals announced by WHO and the Centres for Disease Control. Our study clearly confirms that various antibiotic resistance mechanisms do not affect the bactericidal activity of NCT, making it promising for the treatment of resistant infections.
Problem Based Learning Terhadap Kemampuan Berpikir Kreatif Peserta Didik pada Materi Statistika
Authors: Puji Astuti Fitroh , Destiniar Destiniar , Ningsih Yunika Lestaria 
Published: December 2023

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran problem based learning terhadap kemampuan berpikir kreatif pada materi statistika kelas XI SMK Negeri 1 Palembang tahun ajaran 2022/2023. Metode yang digunakan dalam penelitian ini adalah eksperimen. Penelitian dilaksanakan mulai tanggal 23 Mei 2023 sampai dengan 3 Juni 2023. Subjek penelitian ini adalah kelas XI AKL 2 sebagai kelas eksperimen yang diajarkan dengan menggunakan model pembelajaran Problem Based Learning dengan jumlah peserta didik sebanyak 34 orang, dan kelas XI AKL 3 yang diajarkan menggunakan kelas kontrol dengan menggunakan pembelajaran konvensional dengan jumlah peserta didik sebanyak 31 orang. Bentuk desain metode eksperimen yang digunakan yaitu Posttest Only Control Design. Teknik pengumpulan data menggunakan tes essay tertulis yang mengacu pada indicator kemampuan berpikir kreatif. Teknik analisis data dalam penelitian ini menggunakan deskriptif kuantitatif, dengan melibatkan uji normalitas, uji homogenitas, dan uji hipotesis. Hasil analisis data menunjukkan bahwa data kemampuan berpikir kreatif peserta didik berdistribusi normal, memiliki varians yang homogen. Lalu hasil uji hipotesis dengan statistik uji-t menunjukkan bahwa terdapat perbedaan rata-rata antara dua kelas. Dengan demikian dapat disimpulkan bahwa terdapat pengaruh model pembelajaran Problem Based Learning terhadap kemampuan berpikir kreatif pada materi statistika kelas XI SMK Negeri 1 Palembang.
ЦИФРОВІЗАЦІЯ ТА ШТУЧНИЙ ІНТЕЛЕКТ ДЛЯ ОРГАНІЗУВАННЯ ПРАЦІ МЕНЕДЖЕРІВ ВИРОБНИЧОГО ПІДПРИЄМСТВА
Authors: СВАТЮК Оксана 
Published: December 2023

Наукові дослідження відбуваються за трьома напрямами: 1) цифрова трансформація та управління підприємством; 2) штучний інтелект у виробництві; 3) оптимізація виробництва та інтелектуальний менеджмент.
Ефективність цифровізації кооперації та поділу праці полягає в забезпеченні: раціонального використання робочої сили, оцифрованих засобів праці, безперервності виробничих процесів, ритмічного виконання робіт, підвищення продуктивності праці, встановлення раціональних соціально-трудових взаємовідносин між учасниками виробництва чи збуту, узгодження інтересів персоналу, підвищення якості трудового життя на основі ISO.
Останнім узагальнюючим напрямом щодо праці та її удосконалення є впровадження штучного інтелекту. Важливе місце для цифровізації праці займає організаційна структура та зміни функцій у кожному підрозділі управління ТОВ «СЕ Борднетце-Україна». Раціональність цифровізації визначає успішність діяльності менеджерів підрозділів, функції у поєднанні з штучним інтелектом, повноваження та відповідальність управлінського персоналу, що окреслено у таблиці1.
Штучний інтелект вносить значні зміни в основні напрямки цифровізації та організації праці підрозділів та кооперації праці в управлінні персоналом. Нами наведено три пропозиції: 1.Автоматизація кваліфікаційного підрозділу праці. 2. Цифрова (електронна) кооперація та виробничі системи. 3. Аналіз та оптимізація соціально-трудових взаємовідносин.
Fire and biological protection of paper and corrugated board with an impregnating composition
Authors: Tsapko Yuriy , Bondarenko Olga , Tsapko Аleksey , Zherebchuk Diana 
Published: December 2023

The issue of fire protection of cellulosic materials has been studied in the works of domestic and foreign scientists. However, there are still a number of unresolved problems in this area: modern means are not effective enough, the treated products are unaesthetic, do not meet performance indicators, and do not resist biodegradation. It has been established that volatile mixtures of pyrolysis products differ significantly in the content of combustible gases. Thus, for the treated samples, the amount of methane decreases by 30 times, hydrogen – by 25...30 times, carbon monoxide – by 35...40 times, and the amount of non-combustible gases increases: carbon dioxide - by 1.2...2 times, nitrogen – by 1.4...5 times. Studies on determining the smoke-forming capacity of untreated and treated paper samples showed an 8-fold decrease in the smoke-forming coefficient for treated paper samples and their transition from the group of materials with high smoke-forming capacity (untreated samples) to the group of materials with moderate smoke-forming capacity. Tests were conducted to determine the flammability of corrugated cardboard samples used for packaging various materials, including combustibles: untreated samples are classified as flammable materials, and treated samples are classified as flammable materials with a 42.38 kg/m3 absorption of the impregnating composition in terms of anhydrous substance.
Studies have been conducted on the fire and biological protection of paper and products made of it with an impregnating composition that can effectively protect against fire and biological degradation without compromising the aesthetic and operational characteristics of these materials, taking into account modern environmental requirements. To determine the flame retardant effect of the impregnating composition, thermal destruction of untreated and treated paper samples was performed. In the course of the study, volatile products of thermal degradation were collected and their gas chromatographic analysis was carried out.
Modelling of soil destruction process by bulldozer using a spatially oriented working unit
Authors: Rashkivskyi Volodymyr , Fedyshyn Bogdan 
Published: December 2023

The article uses approaches to creating a model for calculating soil cutting forces by spatially oriented working units of construction machines used on construction sites. The use of such a model is due to the need for continuous improvement of existing equipment and the creation of new ones, taking into account the existing needs. Today, there is a need for efficient performance of construction works related to the operation of construction equipment with dumping equipment. This, in turn, poses the task of determining the performance of mechanised earthworks in various working environments, one of the most common in Ukraine being marl clay, loam and argillaceous clay.
The main method of mechanical soil development is cutting. The main geometric conditions are the position of the cutting wedge edge relative to the cutting direction and the surface of the massif, the outline of the cutting edge, the outline and number of working surfaces of the cutting wedge, the number of so-called side cut surfaces and the so-called blocked cut surfaces. The peculiarity of the digging process is that its power and energy indicators depend on the kinematic conditions and geometric parameters – thickness, width and area of the cut, as well as on the angles of orientation of the working unit in space.
The computational model was created in accordance with the working hypothesis, where the movement of spatially oriented knives moves perpendicular to the blade equipment, at different ratios of the blade movement speed and knife movement, which creates spatial interaction with the working environment, and the deviation of the application of the full cutting force by an angle α.
In accordance with the working hypothesis, we obtained five plans for the movement of the spatially oriented blade of the blade. Depending on the plan of movement of the spatially oriented knife, its geometric interaction with the working environment changes and the cutting force changes accordingly.
The need to create more productive and efficient earthmoving equipment requires the use of modern design solutions. In the course of the study, a model for calculating the cutting of soils by spatially oriented earthmoving tools in the form of a dihedral knife of dump equipment was created. A comparison of soil cutting forces at different depths during the operation of a spatially oriented working body is also proposed. The results are summarised in the form of tabular data and graphs.
Fracture Resistance of Premolars Restored with Inlay/Onlay Composite and Lithium Disilicate CAD/CAM Block Restorations (An In Vitro Study)
Authors: Jamal Mohammed , Hassan Jasim Haider 
Published: December 2023

Aim: To assess the fracture resistance of Premolars restored with inlay and onlay composite and E-max CAD/CAM block restoration.
Material and method: Randomly, fifty maxillary premolar teeth were separated into three major groups: The first group was left unaltered (control group), while the other two groups were prepared with inlay and onlay cavities and restored with lithium disilicate blocks (IPS E.max CAD) and ceramic blocks (Cerasmart). Restorations were bonded using adhesive resin cement (RelyX Ultimate). All samples were thermocycling 500 cycles, between 5 to 55°C, and the cycle time was set at the 30s. The specimen was undergone compressive axial loading in a universal testing machine till the fracture occurred. The result was analyzed using one-way ANOVA, and LSD tests with a significance level set at 0.05.
Result: There were no significant differences in means between the control group and the inlay groups that were restored with Emax and Cerasmart (P >.05).but, the control group has significantly higher means than onlay groups restored with Emax and Cerasmart (P< .05). The two materials show comparable results in both designs.
Conclusion: The fracture resistance of inlay-prepared teeth showed comparable strength to the intact teeth. Conversely, the fracture resistance of onlay-prepared teeth is comparatively lower than intact teeth. The two materials show comparable results irrespective of cavity design.
The Influence of NiTi File Design Features on the Apically Extruded Debris During Endodontic Treatment A concise reviews
Authors: B. Al-Saffar Farah , A. Al-Gharrawi Hikmet 
Published: December 2023

Expelling debris and irrigating solution during cleaning and shaping is an inevitable incidence during endodontic treatment. Any irritation of the periapical area can initiate a flareup situation which can affect the prognosis of endodontic treatment. Thus, Controlling the amount of apically extruded debris increases the success rate of endodontic treatment. Furthermore, the incidence of flare-ups during endodontic treatment can be reduced by selecting the NiTi file system with the lowest apically extruded debris. Despite the advances in endodontic file design that aims to conservatively prepare the apical third of root canals, extruding debris toward the apex is still a non-eliminated issue with all instrumentation systems. The purpose of this review is to identify the effect of each design characteristic on the amount of debris expelled beyond the apical foramen. The strategy of this review focused on reviewing specific electronic databases, time, keywords, and standardized methods. Literature reviewing included studies from almost 20 years ago and up to 2022. In conclusion, the design of the NiTi endodontic file has a significant impact on the amount of apically extruded debris.
The Impact of Strategic Cohesion on Administrative Excellence
Authors: Hussein Jassem Thuraya , Abdel-Wadoud Taher Adel 
Published: December 2023

يهدف هذا البحث الى لاختبار تأثير التماسك الاستراتيجي و أبعاده (الإثارة التنظيمية ، السبك التنظيمي ، التظافر التنظيمي) كمتغير مستقل في التميز الإداري كمتغير تابع في وزارة التخطيط من خلال استطلاع آراء عدد من الموظفين (المدراء العامين ، ورؤساء الأقسام ، ومسؤولي الوحدات الادارية) كمجتمع للدراسة . اعتمد الباحثان المنهج الوصفي التحليلي في إجراء هذا البحث باستطلاع رأي عينة البحث وكان عددهم (155) بعد حصرهم الكامل ، وزعت عليهم (155) استبانة ، تم استرجاع (114) منها ، تم استبعاد (4) منها ، لتكون (110) صالحة للتحليل الإحصائي ، بحيث كانت العينة مقصودة ونسبية. تم توزيع استبيان كأداة رئيسية في جمع البيانات ، بالإضافة إلى المقابلات الشخصية التي أجريت كأداة ثانية تساعد في جمع البيانات ، واستخدم الباحثان عددًا من الأساليب الإحصائية ضمن البرنامج SPSS في تحليل البيانات ، منها على سبيل المثال (تحليل العامل التأكيدي والاستكشافي ، والمتوسط الحسابي ، والانحراف المعياري ، ومعامل ارتباط بيرسون ، والانحدار الخطي البسيط والمتعدد) ، وواحد من أبرز النتائج التي تم التوصل إليها وجود تأثير للتماسك الاستراتيجي وأبعاده في التميز الإداري ، ومن أهم التوصيات ضرورة أن تتبنى وزارة التخطيط التماسك الاستراتيجي والتركيز عليه للوصول إلى التميز الذي تسعى إليه الوزارة للوصول إلى أهدافها ورؤيتها ورسالتها.
Financial Variables and Their Effects on The Development of Bank Credit and Productive Sectors in Iraq Using a Path Analysis Model
Authors: Ali Yahya Hassan Saif , Mahdi Abbas Al-Birmani Salah 
Published: December 2023

هدفت الدراسة إلى قياس وتحليل الآثار المباشرة وغير المباشرة للمتغيرات المالية (الإنفاق العام ، الإيرادات العامة، الدين الداخلي، الدين الخارجي) على القطاعات الإنتاجية غير النفطية مع الائتمان المصرفي وبدونه كمتغير وسيط، وذلك باستخدام بيانات ربع سنوية للمدة (2021Q4-2004Q1)، وتم تحويلها باستخدام Eviews12، ومن أجل قياس هدف الدراسة، تم استخدام أسلوب نموذج تحليل المسار باستخدام IBM SPSS-AMOS، وخلصت الدراسة إلى أن الآثار المباشرة وغير المباشرة للمتغيرات المالية لها دور ضعيف في توجيه الائتمان المصرفي نحو القطاعات الإنتاجية في العراق والتي بلغت (0.18) نتيجة لمخاطر السوق أو عدم استقرار التوقعات في الاقتصاد، بالإضافة إلى ضعف التصنيف الائتماني للمقترضين هذا من جانب، ومن جانب آخر فإن غالبية الائتمان الممنوح من الجهاز المصرفي العراقي قد وجه صوب قطاع التشييد والبناء نتيجة الضمانات التي يستطيع هذا القطاع توفيرها مقارنةً بالقطاعات الانتاجية الأخرى. كما أن المتغيرات المالية من ناحية أخرى لم تكن داعمة في توجيه الائتمان المصرفي نحو تنمية هذه القطاعات في الناتج المحلي الإجمالي للدولة، لأن النتائج التي عكستها الآثار المباشرة وغير المباشرة للمتغيرات المالية ضعيفة في دعم القطاعات الإنتاجية مع أو بدون الائتمان المصرفي. (لا سيما وأن الدين المحلي كان ينافس القطاع الخاص في الحصول على الائتمان المصرفي وهذا ما يسمى بأثر المزاحمة).

نوع البحث: ورقة بحثية.
Vesicular-digestive fistulas in cholelithiasis with concomitant pancreatitis
Authors: Podoluzhny V. I. , Pelts V. A. , Radionov I. A. , Startsev A. B. , Pavlenko V. V. 
Published: December 2023

Aim — evaluation of the incidence of pressure ulcers and vesicular-digestive fistulas in cholecystolithiasis, concomitant chronic pancreatitis, as well as the incidence and effectiveness of basic diagnostic studies of gallstone small bowel obstruction in these patients.
Materials and methods. Over the past 10 years, we have analyzed 5055 cholecystectomies in the surgical department No 2 of the Kuzbass Clinical Emergency Hospital n. a. M. A. Podgorbunsky. In terms of anamnesis, 509 people in this group were treated for chronic pancreatitis, 116 had diabetes mellitus. We have analyzed the surgical treatment of 1086 patients with acute mechanical intestinal obstruction in the surgical department No 1 from 1997 to 2020, gallstone ileus was in 4 operated.
Results. At 5055 cholecystectomies, 10 (0.19%) cases of biliodigestive fistulas were found, including 4 (0.08%) vesicular-duodenal and 6 (0.12%) vesicular-colonic fistulas. In 3 cases, patients underwent long-term treatment for chronic pancreatitis, one patient suffered from diabetes mellitus. Cholecystectomy was successfully combined with bowel suturing. Among 1086 patients, urgently operated on with mechanical intestinal obstruction, gallstone ileus was detected in 4 patients (0.37%). Convincing indications for surgical treatment were vomiting and paretic expansion of the initial sections of the small intestine with a delay in the advancement of barium suspension during its contrasting. Enterotomy and lithoextraction were performed in elderly patients.
Conclusion. Vesicular-duodenal fistulas are formed in 0.08% of cases upon long-term cholecystolithiasis, surgeons detect vesicular-colonic fistulas in 0.12% during cholecystectomy. 30% of these patients received treatment for chronic pancreatitis. Cholelithiasis small bowel obstruction occurs in 0.37% of those operated on with mechanical intestinal obstruction. Diagnostic difficulties do not arise upon using radiation methods of examination.
Cholesterosis: is it related to pancreatology?
Authors: Gubergrits N. B. , Byelyayeva N. V. , Lukashevich G. M. , Borodiy K. N. 
Published: December 2023

Gallbladder (GB) cholesterosis is a disease characterized by impaired cholesterol metabolism with its predominant deposition in the GB wall. GB cholesterosis is considered as a component of lipid distress syndrome, i. e. a combination of a range of pathological conditions caused by lipid metabolism disorders (atherosclerosis, lipogenic pancreatitis, GB cholesterosis, fatty hepatosis). Indeed, GB cholesterosis is often detected in patients with coronary atherosclerosis, hypertension, obesity, and non-alcoholic steatohepatitis. This allows us to consider the GB as a target organ in atherogenic dyslipidemia and point out that its lesion is not as an independent disease, but a systemic manifestation of impaired cholesterol metabolism in the liver.
Considering the general pathogenetic factors of the development of gallstone disease and GB cholesterosis, as well as its frequent combination with cholecystolithiasis, some authors consider GB cholesterosis a specific option of gallstone disease or the pre-stage of cholecystolithiasis, justifying this by the decrease in nucleation time of GB bile upon the absence of stones in patients with GB cholesterosis, as well as with gallstone disease.
Clinical manifestations of GB cholesterosis have not been sufficiently studied. They are nonspecific and do not allow differentiating it from other chronic GB diseases. The relevant symptoms in GB cholesterosis are due to the addition of cholecystitis, cholecystolithiasis or dysfunction of the biliary tract.
Sonography is considered the most informative technique for diagnosing GB cholesterosis. This study is especially informative in case of polypous form of GB cholesterosis. According to the results of sonography, reticular, polypous (pseudopolypous), calculous and mixed forms of GB cholesterosis are distinguished.
The use of ursodeoxycholic acid preparations in GB cholesterosis is pathogenetically substantiated. Ursonost (Organosyn LTD) is one of the best drugs.