bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review of Surgical Irrigation Solutions for Infection Prevention in Orthopaedic Surgery
Authors: Chambers MaKenzie M. , Namdari Surena 
Published: December 2023

» Intraoperative surgical irrigation is a common practice in orthopaedic procedures, although there is no universally established standard of care due to a lack of concrete data supporting an optimal irrigation agent.» Isotonic normal saline has long been considered a safe and cost effective solution for wound irrigation as compared with other antibiotic and antiseptic irrigation solutions.» Currently, the only adjunct to saline that is formally supported by American Academy of Orthopaedic Surgeons, the Centers for Disease Control and Prevention, and World Health Organization is povidone-iodine.» Further in vivo clinical studies are needed to identify the ideal irrigation solution that carries low cytotoxic effects while also exerting optimal antimicrobial properties.
Composition and Sources of Clastic Material of Terrigenous Rocks of the Khabarovsk Accretionary Complex (Sikhote-Alin)
Authors: Mednikov S.M. , Kudymov A.V. , Kruk N.N. , Demonterova E.I. , Didenko A.N. , Oto S. , Peskov A.Yu. 
Published: December 2023

Abstract
––The results of comprehensive studies of terrigenous rocks of the Khabarovsk Sikhote-Alin accretionary complex are presented. It is established that the fragments of Jurassic and Permian–Triassic sandstones are dominated by poorly rounded and poorly separated material mainly from local provenance areas. The detrital part of the rocks is mainly represented by quartz, in a smaller amount by feldspar and rock fragments. Sandstones are characterized by high silica content, moderate alumina content, low concentrations of femic elements and calcium, moderate alkali content with significant variations in the K/Na ratio. Both Jurassic and Permian–Triassic rocks are typically characterized by reduced contents of LILE, REE, to a lesser extent HFSE and negative values of the ɛNd(T) parameter – compared to PAAS. The model Nd age of Jurassic sandstones varies from 1.36 to 1.71 Ga, Permian–Triassic – from 1.14 to 1.35 Ga. Most of the detrital zircon population is of late Paleozoic–early Mesozoic age, approximately 25% are older (pre-Paleoproterozoic). The studied sandstones are mainly rocks of the first cycle of weathering (petrogenic), formed during the erosion of igneous rocks of felsic composition. The synthesis of the obtained data suggests that the main source of the cluster material for the Mesozoic sedimentary rocks was the geological formations of the northern part of the Bureya–Khanka superterrane (Bureya and Malokhingan blocks), as well as, possibly, the eastern part of the Mongol–Okhotsk belt. The Khabarovsk terrane has not drifted significantly along the Tan Lu stike-slip system and is an “autochthonous” block in the present-day structure of Sikhote-Alin.
Is evolutionary psychology a scientific revolution? A bibliometric analysis
Authors: Zagaria Andrea 
Published: December 2023

Abstract

In recent times, David Buss (2020) has claimed that Evolutionary Psychology (EP) represents a genuine "scientific revolution”. This paper aims to conduct a bibliometric analysis of the prevalence of the evolutionary approach in Psychology. EP (broadly defined) is juxtaposed with its classical counterpart, the Standard Social Science Model (SSSM). According to Kuhn's framework, a discipline undergoing a scientific revolution evolves into the dominant school of thought, eclipsing all other theories. The analysis uncovers that the SSSM enjoys significantly greater prominence than EP and is advancing at a swifter pace. The data also indicates a “cultural evolutionary” approach is somewhat lacking (i.e. cross-fertilization between EP and SSSM is not evident). Despite sharing the aspiration for an evolutionary revolution in psychology, it is contended that, for this purpose, a prudent approach involves recognizing the current status of affairs, envisioning realistic change, and building a more methodologically diverse research community.
Meckel's diverticulum with a mesodiverticular band causing massive bowel gangrene- A Case Report
Authors: Babu Basil , Nagaraj Satish Subbiah , Sharma Swastika 
Published: December 2023

Abstract
Introduction
Meckel’s diverticulum is the most common congenital anomaly of the gastrointestinal tract. The anatomy of Meckel’s diverticulum varies and when it is attached to the abdominal wall or mesentery by means of fibrous cords it can cause obstruction including massive bowel gangrene which has not yet been reported in literature.
Case Presentation
A middle-aged man presented to the emergency wing with a history of obstipation and vomiting for 2 days. A CECT abdomen revealed dilated ileal bowel loops with multiple strictures, mesenteric lymph nodes, and mild ascites. With a provisional diagnosis of tuberculosis of the abdomen, he was taken for emergency laparotomy. Around 200 cm of distal ileum was found gangrenous due to the herniation of it beneath a mesodiverticular band which was connected to the apex of Meckel’s diverticulum found 50 cm from the ileocolic junction. The gangrenous bowel along with the gangrenous Meckel’s diverticulum was resected and an end ileostomy and distal mucosal fistula were made.
Conclusions
Meckel’s diverticulum must be kept as a differential in any young patients presenting with acute intestinal obstruction with no previous history of abdominal surgery, TB abdomen, or inflammatory bowel disease. While recommendations suggest resection of symptomatic Meckel’s diverticulum with a narrow base and wide body due to its propensity to rotate along its axis and cause gangrene of Meckel’s diverticulum, we believe Meckel’s diverticulum with a band attaching it to umbilicus or with ileal mesentery must be considered for resection to prevent grave complications.
Morphological insights into the 3-Dimensional Complexity of Rhodolith Beds
Authors: Rubau Andrea Cabrito , de Juan Silvia , Hinz Hilmar , Maynou Francesc 
Published: December 2023

Abstract

The ecological importance of rhodolith beds lies in the fact that they are a structurally complex three-dimensional habitat formed by free-living red calcareous algae. The habitat complexity increases the ecological niches for cryptofauna and provide refuge for a high number of organisms, which is why they are considered biodiversity hotspots. Their structural importance is due to their great variety of complex and branching morphologies that create interstitial spaces between the nodules and increase their surface area. In this work, we study a rhodolith bed located in the Menorca Channel, formed by several species of red calcareous algae, that exhibit a great variety of morphologies that form an extensive and heterogeneous habitat. This study further explores the morphological diversity of this rhodolith bed, comparing the ‘core habitat’ (the best -preserved area) with the boundaries or ‘adjacent area’ where rhodolith density is lower. Our results suggest that all growth forms of rhodoliths (branched, pralines and boxwork) in the core habitat have higher interstitial space and are larger than the ones from adjacent zones. Moreover, we explore three-dimensional techniques to study morphological metrics that have historically been studied in two dimensions. The results of this study reinforce the use of three-dimensional measurements to provide more realistic data of their forms and the use of the interstitial space (IS) of branched rhodoliths as a proxy for habitat complexity. This study contributes to the knowledge of morphological diversity in deep well preserved rhodoliths beds from the North-Western Mediterranean Sea.
Localized molecular chaperone synthesis maintains neuronal dendrite proteostasis
Authors: Ugalde Maria Vera , Alecki Célia , Rizwan Javeria , Le Phuong , Jacob-Tomas Suleima , Xu Jia Ming , Minotti Sandra , Wu Tad , Durham Heather , Yeo Gene 
Published: December 2023

Abstract

Proteostasis is maintained through regulated protein synthesis and degradation and chaperone-assisted protein folding. However, this is challenging in neuronal projections because of their polarized morphology and constant synaptic proteome remodeling. Using high-resolution fluorescence microscopy, we discovered that neurons localize a subset of chaperone mRNAs to their dendrites and use microtubule-based transport to increase this asymmetric localization following proteotoxic stress. The most abundant dendritic chaperone mRNA encodes a constitutive heat shock protein 70 family member (HSPA8). Proteotoxic stress also enhanced HSPA8 mRNA translation efficiency in dendrites. Stress-mediated HSPA8 mRNA localization to the dendrites was impaired by depleting fused in sarcoma—an amyotrophic lateral sclerosis-related protein—in cultured mouse motor neurons and expressing a pathogenic variant of heterogenous nuclear ribonucleoprotein A2/B1 in neurons derived from human induced pluripotent stem cells. These results reveal a crucial and unexpected neuronal stress response in which RNA-binding proteins increase the dendritic localization of HSPA8 mRNA to maintain proteostasis and prevent neurodegeneration.
Who claims the federal adoption tax credit? Those who know about it
Authors: Wallace Cullen 
Published: December 2023

Abstract

This research investigates which individuals are aware of and claim the federal adoption tax credit. Using a probit model, I find that the probability that one claims the credit increases with one’s income and is lower for Black adoptive parents compared to White ones. These discrepancies in usage stem from different probabilities of knowing about the credit. However, conditional on awareness, I find that the probability of claiming the credit is no different among members of differing income or racial groups, implying that a direct way to increase takeup of the tax credit could simply be increasing awareness of it.
JEL codes: H24; J13; J15
The Analysis of Peripheral Pulse Analyzer (PPA) Waveforms
Authors: Deshmukh Manjusha 
Published: December 2023

Abstract

Background
Peripheral Pulse Analyser (PPA) is developed by Bhabha Atomic Research Centre (BARC) Mumbai. The recording of peripheral pulses is a highly important and necessary non-invasive technology used by clinicians to diagnose numerous disorders. Nonexperts may struggle to estimate waveforms accurately; motion artefacts may emerge during tonometry measurements if the skin-sensor contact pressure is insufficient. The aim of waveform analysis was to study differentiating parameters of PPA waveforms for early disease detection.
Methods
We used 70 subjects in two groups as healthy and unhealthy subjects. The pulse morphology is seen to be different in healthy and unhealthy subject. Each PPA signal repeats two or three pulse morphologies. Study was performed at Saraswati College of Engineering (SCOE), Kharghar in collaboration with Board of Research in Nuclear Sciences (BRNS).
Findings: With peaks and valleys different parameters were introduced for eight pulse morphologies (P1 to P8). Polarity, amplitude and intervals are key parameters for waveform analysis of P1 to P8.
Novelty: Automatically analysed blood flow variation of datasets can be used to classify the patterns into various classes to detect diseases. Each PPA signal repeats two or three pulse morphology for the duration of 300 seconds. These pulse morphologies differ in healthy and unhealthy subject. The percentage of pulse morphologies in each PPA signal decides diseases like hypertension, diabetes, and coronary artery diseases (CAD) etc. The waveforms are analysed and tested and are used for disease detection. we have obtained satisfactory results with 96% accuracy.
Assessment of bacterial communities and residual chlorine dynamics within underground and overhead water storage tanks
Authors: Javed Aiza , Amjad Hira , Hashmi Imran 
Published: December 2023

Abstract
Biofilms are primary reservoirs for microbial communities within drinking water distribution systems (DWDSs) and exert considerable influence on the overall safety and quality of potable water. The current study centered on investigating the development of biofilms within water storage tanks of National University of Sciences and Technology (NUST) Islamabad, Pakistan. Two types of tank materials, Polyvinyl Chloride (PVC) and Reinforced Cement Concrete (RCC), were selected to study the impact of the material and residual chlorine on biofilm formation. This study analyzed biofilm development on these materials over 15 and 30 days, demonstrating the evolving biofilm dynamics over time. The findings revealed that water samples showed a high degree of bacterial contamination, with biofilm formation on both PVC and RCC surfaces attributed to low residual chlorine levels. The study also scrutinized the differences between PVC and RCC surfaces, highlighting their varied biofilm growth potentials. Bacterial quantity through Heterotrophic Plate Count (HPC) and images obtained from Scanning Electron Microscopy (SEM) showed that RCC surfaces promote denser biofilm growth owing to their roughness. Moreover, most biofilm samples showed more growth over 30 days time period compared at 15 days. Elemental analysis using Energy Dispersive X-ray Spectroscopy (EDX) revealed increased carbon content in biofilms, suggesting the role of organic compounds in microbial nourishment. This study underscores the significance of material selection for water distribution systems with rough surfaces, such as RCC, potentially promote enhanced bacterial attachment and proliferation. Moreover, current findings highlighted the significance of maintaining adequate residual chlorine levels to inhibit biofilm formation.
Assault related traumatic brain injury hospitalizations in Canada from 2010 to 2021: rates, trends and comorbidity
Authors: Saxena Shikha , Zutrauen Sarah , McFaull Steven R. 
Published: December 2023

Abstract
Background
Traumatic brain injury (TBI) is a major cause of morbidity and mortality globally, and is often associated with complex physical or psychological symptoms resulting in high hospitalization costs. However, TBI epidemiology varies significantly by external cause. TBI related to assault is a distinct clinical group with greater comorbidities and caregiver burden. Current evidence on assault related TBI needs is limited in Canada. This study examined the annual rate, comorbidity, and length of stay associated with assault related TBI hospitalizations and compared it with other external causes, by age and sex in Canada from 2010 to 2021.
Methods
The Discharge Abstract Database (DAD) was used to extract cases of TBI (2010 to 2021). ICD-10-CA codes were used to classify all cases with TBI as per assault and other external causes (falls; transport; sport, physical activity and recreation; struck by). Additional variables, including age, sex, comorbidity and length of stay were examined. Time trends were quantified using Joinpoint regression.
Results
The average annual percent increase for all TBI hospitalizations from 2010 to 2021 was not significant at 0.1%. Females accounted for 35.8% of total TBI hospitalizations. From 2010 to 2021, assault related TBI hospitalizations showed a significant annual decline of 3.6% for males and a significant increase of 1.7% for females. TBI hospitalizations related to falls showed an average annual percent increase of 1.4% for males and 2.2% for females. A significant decrease was observed for TBI hospitalizations related to the other three (transport, SPAR and struck by) external causes for both sexes from 2010 to 2021. Infants and children under 10 years of age had higher percentages of cases with comorbidities and higher length of stay for assault related TBI hospitalizations.
Conclusions
Assault related TBI hospitalization rates decreased overall and among males, rates among females increased from 2010 to 2021. These results underscore the importance of targeted prevention efforts for TBI related to different external causes, age and sex, and continued surveillance to monitor the epidemiology of assault related TBI.
Metformin Alleviates CCl 4 -Induced Acute Liver Injury in IL-33-Overexpressing Mice by Targeting Mitochondrial Pathway-Dependent Oxidative Stress and Inflammation
Authors: Wu Ying , sun Liankun , Gao Weinan , Zhang Wenda , Shen Luyan , Li Yang , Yu Huimei , Dong Delu 
Published: December 2023

Abstract
Background：The liver is the main organ that coordinates metabolic flexibility and participates in nutrient metabolism; and liver injury caused by alcoholic hepatitis, viral hepatitis or fatty liver has become increasingly more prevalent. Thus, it is urgent to explore the specific mechanisms that underlie the pathology of liver injury. Current research focuses on oxidative stress and inflammation as the major causes of acute liver injury, and interleukin-33 (IL-33) is thought to have an integral role, though its contributing mechanisms remain unclear.
Methods：In the present study, we evaluated the coordinated roles of stress and inflammation in CCl4-induced acute liver injury in IL-33-overexpressing mice.
Results：Our results demonstrate for the first time that concurrent treatment with the mitochondrial respiratory chain complex 1 inhibitor metformin enhances mitochondrial biosynthesis and alleviates acute liver injury in IL-33-overexpressing mice with CCl4-induced injury.These results were supported by the ability of metformin to reverse changes in liver tissue pathology, AST/ALT levels, inflammatory and stress related signaling pathways, oxidative response markers, and mitochondrial respiratory chain complex subunits.
Conclusion： These results provide a mechanistic basis for the activity of metformin in alleviating acute liver injury. Metformin alleviates CCl4-Induced acute liver injury in IL-33-Overexpressing mice by targeting mitochondrial pathway-dependent oxidative stress and inflammation. When CCl4 was used as a strong stressor of liver injury, IL-33+ mice were more adaptive to the stress response, resulting in better effectiveness of metformin in ameliorating liver injury.
Reducing Yearly Variation In Potato Tuber Yield Using Supplemental Irrigation
Authors: Jiang Yefang , Stetson Tobin , Philips John , Kostic Ana 
Published: December 2023

Abstract
This study investigated the influence of supplemental irrigation (SI) on yearly variation in potato yield in a humid climate. On-farm trials were conducted in four to five fields annually in Prince Edward Island, Canada from 2019 to 2022. The research involved four different treatments: rainfed production (DA) as the control group, irrigation following conventional practices (FA), irrigation guided by soil moisture monitoring (Y100N), and irrigation guided by soil moisture monitoring coupled with a 20% reduction in fertilizer input (Y80N). While a range of russet potato cultivars were used, local standard cultural practices were followed at all sites. In 2019 SI significantly increased the marketable yields (MY). This was primarily attributed to a drought period that extended from July to early August. Similarly, in 2020 SI led to a substantial rise in MY across sites due to growing season (GS) rainfall being significantly lower than the optimal water demand for the potato plant. Conversely, in 2021 and 2022 when GS rainfall surpassed the potato water demand and was evenly distributed, farmers either refrained from irrigating or employed minimal irrigation rates, resulting in negligible MY responses. Yearly comparisons of tuber yield reveal that implementing SI during excessively dry years or years with sufficient but unevenly distributed rainfall can result in tuber yields comparable to those achieved through rainfed cultivation during years characterized by adequate and evenly distributed rainfall. This suggests that SI can effectively reduce the annual variation in tuber yield in a traditionally rainfed production area.
The molecular dissection of TRIM25‘s RNA-binding mechanism provides key insights into its antiviral activity
Authors: Álvarez Lucía , Haubrich Kevin , Iselin Louisa , Gillioz Laurent , Ruscica Vincenzo , Lapouge Karine , Augsten Sandra , Huppertz Ina , Choudhury Nila Roy , Simon Bernd , Masiewicz Pawel , Lethier Mathilde , Cusack Stephen , Rittinger Katrin , Gabel Frank , Leitner Alexander , Michlewski Gracjan , Hentze Matthias W. , Allain Frédéric H. T. , Castello Alfredo , Hennig Janosch 
Published: December 2023

Abstract

TRIM25 is an RNA-binding ubiquitin E3 ligase with central but poorly understood roles in the innate immune response to RNA viruses. The link between TRIM25’s RNA binding and its role in innate immunity has not been established. Thus, we utilized a multitude of biophysical techniques to identify key RNA-binding residues of TRIM25 and developed an RNA-binding deficient mutant (TRIM25-m9). Using iCLIP2 in virus-infected and uninfected cells, we identified TRIM25’s RNA sequence and structure specificity and showed that its binding to specific viral RNA regions is critical for its antiviral activity.
E-Health’s Influence on Cancer Survivors’ Support for Junk-Food Policy: A Moderated-Mediation Analysis
Authors: Li Milano Ming 
Published: December 2023

Abstract

Background Understanding how factors such as e-health use influences junk-food restrictions is crucial for advancing cancer preventive interventions. This study focuses on cancer survivors, examining the role of increased e-health usage in shaping their support for junk-food control policies. It particularly investigates the perceived cancer risk associated with diet and the impact of calorie information awareness.Methods Data for this study were derived from the Health Information National Trends Survey (HINTS 5 Cycle 4), focusing on a sample of 523 cancer survivors (average age: 67.6 years). The study explored: (1) the impact of e-health use (EHU) on support for junk-food control policy (SJCP); (2) the mediation effect of perceived cancer risk of eating (PCRE) on this relationship; and (3) the moderating role of notice calorie information (NCI) on the PCRE-SJCP pathway.Results The study revealed a positive correlation between e-health use and support for junk-food control policy, with each percentage increase in e-health use raising support by 8.1 percentage points. The perceived cancer risk of eating was identified as a pivotal mediator, accounting for 13.6% of the relationship between e-health use and policy support. Notably, the notice calorie information negatively moderated this mediating effect (bp = -0.159).Conclusion E-health use indirectly influences support for junk-food control policy through the perceived cancer risk from diet. This indirect influence is substantial, although notice calorie information tends to weaken this relationship, highlighting the nuanced ways in which cancer survivors form attitudes towards food-related policies.
Understanding the stability behavior of colloidal silica in different alkali environments
Authors: Xing Yi , Wu Zhenyu , Li Yaowen , Gong Juntao , Liu Weili , Song Zhitang 
Published: December 2023

Abstract

In this paper, three different alkalis namely ammonia (NH4OH), ethylenediamine (EDA), and tetrabutylammonium hydroxide (TBAOH) are introduced in the colloidal silica to study the stability and pH is controlled in the range of 8–11. As a result, NH4OH greatly promotes the stability of silica sol at first due to the strong solvation ability of NH4+ and then the stability begins to decrease because the electric double layer of silica is compressed. The introduction of EDA leads to reducing the stability of silica system evidently followed by a slight increase, which can be explained by the cationic bridging effect of ethylenediammonium cations. Meanwhile, the effect of TBAOH on silica dispersion is analogous to EDA, mainly caused by the hydrophobic and steric effects. The abovementioned relevant stability mechanisms are involved in non-DLVO theory.