bluuebunny/crossref_metadata_2025_split huggingface dataset:
STRUCTURAL ANALYSIS OF ACUTE CHEMICAL POISONING IN PERSONS OVER 60 YEARS OF AGE
Authors: Симонова А.Ю. , Ильяшенко К.К. , Белова М.В. , Поцхверия М.М. , Карева М.В. , Асанова Л.Р. , Клюев А.Е. 
Published: November 2023

Население развитых стран стареет. Наряду с увеличением доли лиц старше 60 лет, возрастает и их количество среди пациентов с острыми отравлениями химической этиологии. Цель работы — анализ структуры острых отравлений у лиц пожилого и старческого возраста за период 2020–2022 гг. В рамках ретроспективного когортного исследования проведен анализ данных пациентов 60 лет и старше с острыми отравлениями химической этиологии в период 2020–2022 гг. Установлено, что удельный вес пациентов пожилого и старческого возраста в общей структуре острых отравлений составляет в среднем 3,5 %, из них самую многочисленную группу — лица 60–74 лет (60,2 %), из них женщины — 64,5 %, мужчины — 35,5 %. Выявлено, что в 61,5 % случаев причиной отравления являлся суицид, 38,5 % отравлений носили случайный характер. В структуре острых отравлений у пациентов пожилого и старческого возраста лидируют психофармакологические препараты — 34,1 %, разъедающие вещества — 15,9 %, средства, действующие на сердечно-сосудистую систему, — 12,7 %. Эти же токсиканты являются основной этиологической причиной летального исхода. У пациентов старше 60 лет отмечается высокая летальность — 13,2–22,3 %. Острые химические отравления у пациентов старше 60 лет представляют актуальную медицинскую проблему на современном этапе в связи со значительной частотой возникновения и высокой летальностью и требуют детального изучения для повышения эффективности лечения.
The population of developed countries is aging. Along with an increase in the proportion of people over 60 years of age among the population, their number is also increasing among patients with acute poisoning of chemical etiology. Analysis of the structure of acute poisoning in elderly and senile people for the period 2020–2022. It has been established that the proportion of patients of gerontological age in the overall structure of acute poisonings averages 13,5 %, of which the largest group is persons aged 60–74 years (60,2 %), women — 64,5 %, men — 35,5 %. It was found that in 61,5 % of cases the cause of poisoning was suicide, 38,5 % of poisonings were random. In the structure of acute poisoning in geriatric patients, psychopharmacological drugs are in the lead — 34,1 %, corrosive substances — 15,9 %, drugs acting on the cardiovascular system — 12,7 %. These same toxicants are the main etiological cause of death. Patients over 60 years of age have a high mortality rate from 13,2 to 22,3 %. Acute chemical poisoning in patients over 60 years of age is an urgent medical problem at the present stage, due to a significant incidence and high mortality, and require detailed study in order to improve the effectiveness of their treatment.
BIOELEMENT STATUS OF OLDER AGE RESIDENTS OF MAGADAN
Authors: Луговая Е.А. , Агеенко К.И. 
Published: November 2023

Цель работы — выявление типов биоэлементного статуса на основе выбора дискриминантных переменных в виде концентраций эссенциальных химических элементов у лиц старших возрастных групп. Методами атомно-эмиссионной спектрометрии и масс-спектрометрии в волосах 237 жителей 36–94 лет Магадана определяли содержание Ca, Cu, Fe, K, Mg, Mn, Na, P и Zn. С помощью кластерного и дискриминантного анализа достоверно (p=0,001) в качестве классифицирующих параметров установили концентрации Ca, Mg, Mn и Zn, которые позволили сегментировать массив обследованных по трем вариантам биоэлементного профиля — региональная норма (81,97 % обследованных), избыток (16,87 % обследованных) и гиперизбыток (0,84 % обследованных). Биоэлементный профиль «региональная норма» преобладает во всех исследованных возрастных периодах независимо от пола, и его частота встречаемости увеличивается к старческому возрасту, что характеризует процессы изменения элементного статуса как «нормальное биоэлементное старение». Гиперизбыток встречается только у женщин 2-го зрелого возраста. Профиль «избыток» в большей степени характерен для женщин, у которых его частота встречаемости уменьшается с 33,9 до 4,8 % при переходе от 2-го зрелого к старческому возрасту.
By choosing discriminant variables as concentrations of significant chemicals, this study identified types of mature people bioelement pictures. The inductively coupled plasma atomic emission spectrometry/mass spectrometry method was used to measure Ca, Cu, Fe, K, Mg, Mn, Na, P and Zn concentrations in hair samples of 237 residents of Magadan aged 36–94. By cluster and discriminant analysis the concentrations of Ca, Mg, Mn and Zn were reliably (p=0,001) set as classifying parameters, which made it possible to divide the examinees into three groups based on the following types of bioelement status: regional norm (81,97 % of the surveyed subjects), excess (16,87 %) and hyper excess (0,84 %). The status of regional norm proved to be mostly common in all the studied ages, regardless of gender. We could see the incidence of this bioelement type is growing to the extreme old age being characteristic of the changing element status as normal bioelement ageing. The status of hyper excess was only exhibited by women at their second adulthood. The status of bioelement excess is more common in women who reduce the chance of developing this condition from 33,9 to 4,8 % as they move from second adulthood to senile age.
THIOREDOXIN-REDUCTASE IN FIBROBLASTS OF HUMAN DERMIS IN THE PROCESS OF AGING
Authors: Тасакова О.С. , Голубцова Н.Н. , Гунин А.Г. 
Published: November 2023

Цель работы — исследование содержания тиоредоксин-редуктазы в фибробластах дермы человека от 20 нед беременности до 85 лет, а также выяснение роли тиоредоксин-редуктазы в возрастном изменении численности фибробластов в дерме человека. Тиоредоксин-редуктазу, ядерный антиген пролиферирующих клеток (PCNA), маркер фибробластов виментин выявляли в срезах кожи непрямым иммуногистохимическим методом. Показано, что доля фибробластов с положительной окраской на тиоредоксин-редуктазу в дерме человека увеличивается в диапазоне от 20 нед беременности до 20 лет, не изменяется — с 21 года до 60 лет, снова возрастает — с 61 года до 85 лет. Наибольший прирост доли фибробластов с позитивной окраской на тиоредоксин-редуктазу в дерме происходит в возрастном интервале от рождения до 20 лет. Общая численность и доля PCNA-положительных фибробластов в дерме уменьшались возрастом, наиболее значительно начиная с антенатального периода до 40 лет. Корреляционный анализ показал, что возрастное снижение числа фибробластов и их пролиферативной активности достоверно связано с увеличением процентного содержания фибробластов с положительной окраской на тиоредоксин-редуктазу. Полученные результаты позволяют предположить, что тиоредоксин-редуктазу можно рассматривать в качестве маркера возрастного уменьшения численности и пролиферации фибробластов в дерме человека.
The aim of this work was to examine the content of thioredoxin-reductase in fibroblasts of human dermis from the development until deep aging (from 20 weeks of pregnancy until 85 years old), and defi ning of a role of thioredoxin-reductase in age-dependent changes in the number of fibroblasts in the dermis. Thioredoxin-reductase, proliferating cells nuclear antigen (PCNA), marker of fibroblasts vimentin were detected with indirect immunohistochemical technique. Results showed that portion of fibroblasts with positive staining for thioredoxin-reductase in the dermis is increased from 20 weeks of pregnancy until 20 years old, is not changed from 21 to 60 years old, and is increased again from 61 to 85 years old. Most expressed age related increase in portion of thioredoxin-reductase positive dermal fibroblasts is present form birth until 20 years as compared to antenatal period. General number and percent of PCNA positive fibroblasts in dermis are decreased with age with more expressed changes until 40 years old. Correlation analysis showed that age dependent decrease in the number of fibroblasts and their proliferative activity is significantly associated with increase in thioredoxin-reductase positive fibroblasts in dermis. Results obtained allow to suggest that thioredoxin-reductase plays a role in age dependent decrease in the number of fibroblasts and their proliferation in human dermis.
Realization of cathodoluminescence in the 180 nm spectral range by suppressing thermal stress in mist chemical vapor deposition of rocksalt-structured MgZnO films
Authors: Ogawa Kotaro , Kosaka Wataru , Kusaka Hiroya , Kudo Kanta , Ohno Soichiro , Serizawa Izumi , Ota Yuichi , Yamaguchi Tomohiro , Honda Tohru , Kaneko Kentaro , Fujita Shizuo , Onuma Takeyoshi 
Published: November 2023

Abstract
Rocksalt-structured (RS) Mg
x
Zn1−x
O films with x = 0.65–1.0 were grown on MgO (100) substrate using the mist CVD method. A comparative study of the RS-Mg0.92Zn0.08O films grown under slow and rapid-cooling rates apparently showed simultaneous reductions in the surface pit density, FWHM values for the X-ray diffraction peak, and defect-related cathodoluminescence (CL) for the film grown under the slow-cooling rate. CL spectra for the RS-Mg
x
Zn1−x
O films grown under the slow-cooling rate eventually showed near-band-edge emission peaks in the 180–190 nm spectral range for MgO molar fraction x ≥ 0.92 at RT.
Endocardite Infecciosa Por Hacek: Relato De Caso
Authors: Domingues Anna Luiza Guagliardi , Rostirola Laís Sette 
Published: November 2023

Introdução: A endocardite infecciosa (EI) é uma infecção do endotélio cardíaco que pode ser provocada usualmente por bactérias e fungos. O crescimento superficial destes microrganismos (MOs) pode causar embolia em vários órgãos, como rins, pulmões, pele, cérebro e sistema nervoso central, levando a morte se não tratada adequadamente. A EI provocada por bactérias HACEK (Haemophilus spp., Aggregatibacter actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens e Kingella kingae) afeta principalmente pacientes com doença cardíaca prévia ou válvulas artificiais, e é caracterizada por um curso insidioso, com atraso médio no diagnóstico de um mês (quando provocada por Haemophilus spp.) a 3 meses (quando causada por Aggregatibacter ou Cardiobacterium spp.).
Objetivo: Relatar um caso de EI provocada por MOs do grupo HACEK. Método: Trata-se do relato de um paciente atendido no Hospital Universitário São Francisco na Providência de Deus – HUSF, localizado na cidade de Bragança Paulista - SP.
Relato do Caso: Este relato descreve o caso de um paciente do sexo masculino, 50 anos, com histórico de febre persistente, sudorese, calafrios, fadiga e perda ponderal. Após avaliação clínica, o paciente foi diagnosticado com EI, com base nos achados clínicos, laboratoriais e de imagem, incluindo anemia microcítica, leucocitose com desvio à esquerda, PCR e VHS elevadas, presença de sopro diastólico, além de evidências de comprometimento valvar cardíaco no ecocardiograma transtorácico. Hemoculturas identificaram a bactéria A. aphrophilus como a causa da EI, e o tratamento com ceftriaxona foi iniciado. Devido à disfunção valvar significativa, o paciente foi submetido à cirurgia cardíaca com troca da valva tricúspide por uma prótese mitral, seguido por acompanhamento ambulatorial/cardiológico e avaliação odontológica.
Conclusão: Os MOs HACEK podem provocar EI em pacientes de diversas faixas etárias, incluindo crianças, e sua capacidade de afetar tanto válvulas nativas quanto protéticas ressalta a importância de uma abordagem clínica ampla e de alto índice de suspeita para o diagnóstico preciso. Além disso, a manutenção da saúde bucal e o controle de cáries são fatores importantes para a prevenção dessas infecções, e o uso de exames de imagem, como tomografias e ecocardiogramas, e a realização de culturas sanguíneas desempenham um papel fundamental na identificação e tratamento adequado dos pacientes com EI provocada por este grupo de bactérias. Portanto, a compreensão desses aspectos é essencial para melhorar o diagnóstico e a gestão clínica dessas infecções, que podem levar a morbidade substancial e mortalidade se não detectadas e tratadas a tempo.
Development of an adaptive test of musical scene analysis abilities for normal-hearing and hearing-impaired listeners
Authors: Hake Robin , Bürgel Michel , Nguyen Ninh K. , Greasley Alinka , Müllensiefen Daniel , Siedenburg Kai 
Published: November 2023

AbstractAuditory scene analysis (ASA) is the process through which the auditory system makes sense of complex acoustic environments by organising sound mixtures into meaningful events and streams. Although music psychology has acknowledged the fundamental role of ASA in shaping music perception, no efficient test to quantify listeners’ ASA abilities in realistic musical scenarios has yet been published. This study presents a new tool for testing ASA abilities in the context of music, suitable for both normal-hearing (NH) and hearing-impaired (HI) individuals: the adaptive Musical Scene Analysis (MSA) test. The test uses a simple ‘yes–no’ task paradigm to determine whether the sound from a single target instrument is heard in a mixture of popular music. During the online calibration phase, 525 NH and 131 HI listeners were recruited. The level ratio between the target instrument and the mixture, choice of target instrument, and number of instruments in the mixture were found to be important factors affecting item difficulty, whereas the influence of the stereo width (induced by inter-aural level differences) only had a minor effect. Based on a Bayesian logistic mixed-effects model, an adaptive version of the MSA test was developed. In a subsequent validation experiment with 74 listeners (20 HI), MSA scores showed acceptable test–retest reliability and moderate correlations with other music-related tests, pure-tone-average audiograms, age, musical sophistication, and working memory capacities. The MSA test is a user-friendly and efficient open-source tool for evaluating musical ASA abilities and is suitable for profiling the effects of hearing impairment on music perception.
KESIAPSIAGAAN BENCANA DAN KECEMASAN MASYARAKAT PASKA BANJIR DI DAERAH RAWAN BENCANA
Authors: Sembung Christasya Laurensia , Purnawinadi I Gede 
Published: November 2023

Kesiapsiagaan bencana sebagai suatu proses manajemen bencana berupa kegiatan pencegahan bertujuan untuk mengurangi risiko dan dampak bencana, termasuk dampak psikologis seperti kecemasan pada masyarakat. Penelitian ini bertujuan untuk menganalisis hubungan antara kesiapsiagaan bencana dengan kecemasan pada masyarakat di daerah rawan bencana. Penelitian ini merupakan jenis kuantitatif dengan desain survei analitik melalui pendekatan cross-sectional, data dianalisis melalui uji statistik menggunakan rumus Spearman correlation. Sampel diambil menggunakan teknik total sampling dengan jumlah 72 responden. Instrumen yang digunakan adalah kuesioner Kesiapsiagaan Bencana Banjir dan kuesioner General Anxiety Disorder (GAD-7). Secara deskriptif hasil penelitian menunjukkan bahwa dari 72 partisipan didapati dominan kesiapsiagaan bencana banjir dalam kategori tinggi (36,1%), sedangkan kategori kecemasan dominan sedang (33,3%). Berdasarkan hasil analisis didapati bahwa tidak terdapat hubungan yang bermakna antara kesiapsiagaan bencana dengan kecemasan masyarakat paska banjir (p-value 0,119 > 0,05). Bagi peneliti selanjutnya direkomendasikan melakukan penelitian bukan hanya pada masyarakat atau keluarga yang terdampak banjir, tetapi juga pada masyarakat di sekitar lokasi terjadinya bencana dan penelitian akan lebih baik dilakukan dalam kurun waktu yang tidak terlalu lama paska bencana.

KATA KUNCI: Banjir, Kecemasan, Kesiapsiagaan Bencana

ABSTRACT
Disaster preparedness as a process of disaster management in the form of prevention activities aims to reduce the risks and impacts of disasters, including psychological impacts such as anxiety on the community. This study aimed to analyze the relationship between disaster preparedness and anxiety in people in disaster-prone areas. This research was a quantitative type with an analytic survey design through a cross-sectional approach, data were analyzed through statistical tests using the Spearman correlation formula. Samples were taken using total sampling technique with a total of 72 respondents. The instruments used are the Flood Disaster Preparedness questionnaire and the General Anxiety Disorder questionnaire (GAD-7). Descriptively, the results of the study showed that of the 72 participants, flood disaster preparedness was dominant in the high category (36.1%), while the anxiety category was dominant (33.3%). Based on the results of the analysis, it was found that there was no significant relationship between disaster preparedness and post-flood community anxiety (p-value 0,119 > 0,05). For future researchers, it is recommended to conduct research not only on the community or family affected by the flood, but also on the community around the location of the disaster and research will be better carried out not too long after the disaster.

KEYWORDS: Anxiety, Disaster Preparedness, Flood
A Comparison of Void-finding Algorithms Using Crossing Numbers
Authors: Veyrat Dahlia , Douglass Kelly A. , BenZvi Segev 
Published: November 2023

Abstract
We study how well void-finding algorithms identify cosmic void regions and whether we can quantitatively and qualitatively compare the voids they find with dynamical information from the underlying matter distribution. Using the ORIGAMI algorithm to determine the number of dimensions along which dark matter particles have undergone shell crossing (crossing number) in N-body simulations from the AbacusSummit simulation suite, we identify dark matter particles that have undergone no shell crossing as belonging to voids. We then find voids in the corresponding halo distribution using two different void-finding algorithms: VoidFinder and V2, a ZOBOV-based algorithm. The resulting void catalogs are compared to the distribution of dark matter particles to examine how their crossing numbers depend on void proximity. While both algorithms’ voids have a similar distribution of crossing numbers near their centers, we find that beyond 0.25 times the effective void radius, voids found by VoidFinder exhibit a stronger preference for particles with low crossing numbers than those found by V2. We examine two possible methods of mitigating this difference in efficacy between the algorithms. While we are able to partially mitigate the ineffectiveness of V2 by using the distance from the void edge as a measure of centrality, we conclude that VoidFinder more reliably identifies dynamically distinct regions of low crossing number.
Stellar Outbursts and Chondrite Composition
Authors: Li Min , Zhu Zhaohuan , Huang Shichun , Sui Ning , Petaev Michail I. , Steffen Jason H. 
Published: November 2023

Abstract
The temperatures of observed protoplanetary disks are not sufficiently high to produce the accretion rate needed to form stars, nor are they sufficient to explain the volatile depletion patterns in CM, CO, and CV chondrites and terrestrial planets. We revisit the role that stellar outbursts, caused by high-accretion episodes, play in resolving these two issues. These outbursts provide the necessary mass to form the star during the disk lifetime and provide enough heat to vaporize planet-forming materials. We show that these outbursts can reproduce the observed chondrite abundances at distances near 1 au. These outbursts would also affect the growth of calcium-aluminum-rich inclusions and the isotopic compositions of carbonaceous and noncarbonaceous chondrites.
Inferring Coupling Strengths of Mixed-mode Oscillations in Red Giant Stars Using Deep Learning
Authors: Dhanpal Siddharth , Benomar Othman , Hanasoge Shravan , Takata Masao , Panda Subrata Kumar , Kundu Abhisek 
Published: November 2023

Abstract
Asteroseismology is a powerful tool that may be applied to shed light on stellar interiors and stellar evolution. Mixed modes, behaving like acoustic waves in the envelope and buoyancy modes in the core, are remarkable because they allow for probing the radiative cores and evanescent zones of red giant stars. Here, we have developed a neural network that can accurately infer the coupling strength, a parameter related to the size of the evanescent zone, of solar-like stars in ∼5 ms. In comparison with existing methods, we found that only ∼43% of inferences were in agreement with a difference less than 0.03 in a sample of ∼1700 Kepler red giants. To understand the origin of these differences, we analyzed a few of these stars using independent techniques such as the Monte Carlo Markov Chain method and echelle diagrams. Through our analysis, we discovered that these alternate techniques are supportive of the neural-net inferences. We also demonstrate that the network can be used to yield estimates of coupling strength and period spacing in stars with structural discontinuities. Our findings suggest that the rate of decline in the coupling strength in the red giant branch is greater than previously believed. These results are in closer agreement with calculations of stellar-evolution models than prior estimates, further underscoring the remarkable success of stellar evolution theory and computation. Additionally, we show that the uncertainty in measuring period spacing increases rapidly with diminishing coupling strength.
Toward Machine-learning-based Metastudies: Applications to Cosmological Parameters
Authors: Crossland Tom , Stenetorp Pontus , Kawata Daisuke , Riedel Sebastian , Kitching Thomas D. , Deshpande Anurag , Kimpson Tom , Liew-Cain Choong Ling , Pedersen Christian , Piras Davide , Sharma Monu 
Published: November 2023

Abstract
We develop a new model for automatic extraction of reported measurement values from the astrophysical literature, utilizing modern natural language processing techniques. We use this model to extract measurements present in the abstracts of the approximately 248,000 astrophysics articles from the arXiv repository, yielding a database containing over 231,000 astrophysical numerical measurements. Furthermore, we present an online interface (Numerical Atlas) to allow users to query and explore this database, based on parameter names and symbolic representations, and download the resulting data sets for their own research uses. To illustrate potential use cases, we then collect values for nine different cosmological parameters using this tool. From these results, we can clearly observe the historical trends in the reported values of these quantities over the past two decades and see the impacts of landmark publications on our understanding of cosmology.