bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prescription of anti-influenza drugs in Japan, 2014–2020: A retrospective study using open data from the national claims database
Authors: Sako Akahito , Gu Yoshiaki , Masui Yoshinori , Yoshimura Kensuke , Yanai Hidekatsu , Ohmagari Norio 
Published: October 2023

Background
Both physicians and patients are proactive towards managing seasonal influenza in Japan and six drugs are approved. Although many countries have national influenza surveillance systems, data on nationwide prescription practices of anti-influenza drugs are lacking. Therefore, we aimed to clarify the status of anti-influenza drug use in Japan by analyzing real-world data.

Methods
This retrospective study analyzed open data from the National Database of Health Insurance Claims and Specific Health Checkups, which covers most claims data from national health insurance. We estimated the annual number of patients prescribed anti-influenza drugs, which drugs they were prescribed, the patients’ age and sex distribution, drug costs, and regional disparities for the period 2014–2020.

Results
For 2014–2019, an estimated 6.7–13.4 million patients per year were prescribed anti-influenza drugs, with an annual cost of 22.3–48.0 billion JPY (Japanese Yen). In addition, 21.1–32.0 million rapid antigen tests were performed at a cost of 30.1–47.1 billion JPY. In 2017, laninamivir was the most frequently prescribed anti-influenza drug (48%), followed by oseltamivir (36%), while in 2018, the newly introduced baloxavir accounted for 40.8% of prescriptions. After the emergence of COVID-19, the estimated number of patients prescribed anti-influenza drugs in 2020 dropped to just 14,000. In 2018, 37.6% of prescriptions were for patients aged < 20 years compared with 12.2% for those aged ≥ 65 years. Prescriptions for inpatients accounted for 1.1%, and the proportion of prescriptions for inpatients increased with age, with men were more likely than women to be prescribed anti-influenza drugs while hospitalized.

Conclusions
Based on our clarification of how influenza is clinically managed in Japan, future work should evaluate the clinical and economic aspects of proactively prescribing anti-influenza drugs.
The effects of plant-based dietary patterns on the risk of developing gestational diabetes mellitus: A systematic review and meta-analysis
Authors: Zhu Yu , Zheng QingXiang , Huang Ling , Jiang XiuMin , Gao XiaoXia , Li JiaNing , Liu RuLin 
Published: October 2023

Background
The worldwide prevention of gestational diabetes mellitus (GDM) is a significant health challenge. Plant-based dietary patterns are a series dietary habits that emphasized foods derived from plant sources more and from animal foods less. Now, no consensus exists on the effects of plant-based dietary patterns on the incident of GDM.

Objective
This study aimed to estimate the effects of plant-based dietary patterns on the risk of developing GDM.

Methods
This systematic review was conducted following the checklist of PRISMA. Six electronic databases including PubMed, Embase, Web of Science, China National Knowledge Infrastructure, Wangfang, and Chinese Scientific Journals Database were searched from inception to November 20, 2022. A fixed or random effect model was used to synthesize results of included studies. Then, subgroup analysis, meta-regression and sensitivity analysis were performed to assure the reliability and stability of the results.

Results
Ten studies including 32,006 participants were identified. The results of this study showed that the better adherence to the plant-based dietary patterns was related to the lower risk of developing GDM (RR = 0.88[0.81 to 0.96], I2 = 14.8%). The slightly stronger association between plant-based diets and the risk of developing GDM was found when healthy plant-based dietary pattern index was included in pooled estimate (RR = 0.86[0.79 to 0.94], I2 = 8.3%), compared with that unhealthy one was included (RR = 0.90[0.82 to 0.98], I2 = 8.3%).

Conclusion
The plant-based dietary patterns are associated with a lower risk of developing GDM. Furthermore, healthy plant-based dietary patterns are more recommended than unhealthy one. It is significant to help medical staff to guide pregnant women to choose reasonable diets.
"Factors associated with provider unwillingness to perform induced abortion in Argentina: A cross-sectional study in four provinces following the legalization of abortion on request"
Authors: Vázquez Paula , Nigri Carolina , Pingray Verónica , Gibbons Luz , Formia Sandra , Messina Analía , Castro Claudia , Jacobi Cintia , Martiarena Adriana , Velazco Susana , Langer Ana , Gausman Jewel , Jolivet R. Rima , Williams Caitlin R. , Berrueta Mabel 
Published: October 2023

Background
The 2020 Law on Access to the Voluntary Interruption of Pregnancy is a landmark piece of legislation regarding access to abortion in Argentina. Under the new law, abortion is legal up to 14 weeks and 6 days gestation, with exceptions made to the gestational age limit to save a woman´s life, to preserve a woman´s health, and in case of rape. However, widespread refusal to provide care by authorized health providers (due to conscientious objection or lack of awareness of the new law) could hinder access to legal abortion. This study aimed to assess knowledge of the current legal framework and willingness to perform abortions by authorized professionals in Argentina, to compare perceptions about any requirements necessary to perform abortions on legal grounds between willing and unwilling providers and to explore factors associated with refusal to provide care.

Methods
We conducted a cross-sectional study based on a self-administered, anonymous survey to authorized abortion providers in public health facilities in four provinces of Argentina.

Findings
Most authorized providers knew the grounds upon which it is currently legal to perform abortions; however, almost half reported being unwilling to perform abortions, mainly due to conscientious objection. Both willing and unwilling providers believed there were additional requirements not actually stipulated by law. Using logistic regression, we found that province where providers serve, working in a tertiary level facility, and older age were factors associated with unwillingness to provide care.

Conclusions
The results of our study indicate that, even in a favorable legal context, barriers at the provider level may hinder access to abortion in Argentina. They help to demonstrate the need for specific actions that can improve access such as training, further research and public policies that guarantee facilities have sufficient professionals willing to provide abortion care.
Older adults’ suggestions of research topics on ageing well in urban environments – A participatory study
Authors: Oeser Philip , Bruckmann Nora , Gellert Paul , Herrmann Wolfram J. 
Published: October 2023

Background
Ageing societies and urbanization are global phenomena that pose new challenges for care delivery. It is important to create a scientific evidence base to prepare for these changes. Hence, the aim of our study was to assess which research agenda older adults living in an urban environment in Germany suggest.

Methods
A total of 1000 participants aged 65 years or older from five different neighborhoods of Berlin were randomly chosen and were sent a single item questionnaire allowing them to freely propose research topics regarding ageing well in the city. Codes were developed inductively and clustered into categories. In a second stage, these results were discussed with the participants and local stakeholders in a workshop and video calls.

Results
102 persons suggested 18 research topics in 6 categories: health, living environment, social issues, mobility, and accessibility to information and communication. Proposed research topics ranged from accessibility of health care, green spaces and recreational means to social involvement and loneliness.

Conclusion
There is a substantial interest of older adults for research regarding their living situation. Research projects and local urban planning committees are encouraged to invite older adults to participate and integrate their perspectives suggested by older adults.
Lymphatic filariasis in Zambia: A scoping review protocol
Authors: Shirley Hugh , Orriols Adrienne , Hogan Dylan , Chimfwembe Kingford , Balya Alinaswe , Sibbuku Kaala , Lardizabal Janelle , Tillotson Sophie , Coombs Philip Espinola , Wamai Richard 
Published: October 2023

Background
Zambia is among the countries making major progress in limiting cases of the neglected tropical disease lymphatic filariasis on the path to reaching global elimination targets. For this trend to continue, it is essential for strategies and policies targeting the disease in Zambia to be based on the most recent and relevant literature. The scope of research on lymphatic filariasis in the Zambian context is currently poorly understood. Therefore, this study describes a scoping review protocol which will be used to analyze the body of literature on lymphatic filariasis in Zambia.

Methods
The scoping review protocol was developed following the PRISMA reporting guidelines for Scoping Reviews (PRISMA-ScR) and the JBI Scoping Review Methodology Group’s guidance on conducting scoping reviews. In consultation with a research librarian, these guidelines will be applied to a literature search of articles from peer-reviewed journals, or government and international regulatory bodies using PubMed, Embase, Web of Science, Cochrane CENTRAL, WHO ICTRP, Pan African Clinical Trials Registry, and ClinicalTrials.gov. Each record will be screened at the abstract and full-text level by two independent reviewers, and results reported via summary statistics.

Discussion
Understanding the current state of research on lymphatic filariasis in Zambia will identify major knowledge and intervention gaps in this context, and serve as a source of information for surrounding countries in the region. As the disease prevalence drops, efforts for elimination will require carefully targeted strategies which can be informed from the literature identified in this protocol.
Prognostic factors influencing HIV-free survival among infants enrolled for HIV early infant diagnosis services in selected hospitals in Nairobi County, Kenya
Authors: Kiilu Elizabeth Mueke , Karanja Simon , Kikuvi Gideon , Wanzala Peter 
Published: October 2023

BackgroundDespite being a preventable disease, pediatric HIV infection continues to be a public health concern due to the morbidity and mortality associated with the disease. Vertical transmission of HIV occurs when a mother living with HIV passes the virus to her baby during pregnancy, childbirth, or breastfeeding. Globally, the vertical transmission rate of HIV is 9% with sub-Saharan Africa accounting for 90% of these infections. In Kenya, the national vertical transmission rates of HIV stood at 11.5% by the end of 2018, with a target to reduce vertical transmission rates to below 5% and 2% in breastfeeding and non-breastfeeding infants respectively, by the end of 2021.ObjectiveTo determine the prognostic factors influencing HIV-free survival among infants enrolled for HIV early infant diagnosis (EID) services in selected hospitals in Nairobi County, Kenya.MethodsA prospective cohort study design was adopted. HIV exposed infants were recruited at six weeks to determine HIV-free survival over 12 months follow up. Simple random sampling was used to select 166 infants and data were collected from the mothers using semi-structured interviewer-administered questionnaires. Log-rank tests were used to test for associations at the bi-variable level while Cox-proportional regression was used to analyze data at the multi-variable level, with the aid of STATA 14 software. Ethical approval was obtained from Kenya Medical Research Institute, Scientific Ethics Review Unit.ResultsThe overall infant HIV incidence rate over one-year follow-up was 9 cases per 100 person-years (95% CI: 5.465–16.290). The failure event was defined as an infant with a positive PCR test during the study period with total failures being 13 (9.41%) over 12 months. Prognostic factors associated with poor infant HIV-free survival were young maternal age (18–24 years) and mothers with a recent HIV diagnosis of ≤ 2 years since a positive HIV diagnosis (HR 5.97 CI: 1.20, 29.58) and (HR 6.97 CI: 1.96, 24.76), respectively.ConclusionMaternal prognostic factors associated with poor infant HIV-free survival were young maternal age (18–24 years) and recent maternal HIV diagnosis of ≤ 2 years since positive HIV diagnosis. The study recommended the development of an intervention package with more rigorous adherence counseling and close monitoring for young mothers, and mothers with recent HIV diagnoses.
Tinjauan Terhadap Kebijakan Presidential Threshold dalam Sistem Pemilu di Indonesia
Authors: Khoiriyah Nurul Kimalatul 
Published: October 2023

Pemilihan umum yakni kontestasi terbesar dalam skala nasional yang dilaksanakan lima tahun sekali. Beberapa fakta d temukan bahwa regulasi khusus pemilihan umum dianggap tidak adil. Salah satunya adalah aturan tingkatan yang diterima menominasikan presiden. Konstitusi mengatur bahwasannya partai politik mampu menominasikan presiden dan wakil presiden apabila mereka mempunyai 20% kursi di DPR maupun 25% suara nasional. Peraturan tersebut dianggap tidak relevan apabila dilaksanakan dalam konteks pemilu serentak, karena yang menjadi acuan suara adalah pemilu yang dilaksanakan empat tahun yang lalu. Presidential Threshold beberapakali diajukan oleh para praktisi untuk dilakukan hak uji materi ke Mahkamah Konstitusi. Namun Mahkamah Konstitusi tidak menerima petisi yang diajukan. Mahkamah Konstitusi menganggap Presidential Threshold sebagai salah satu cara untuk memperbaiki system presidensial yang ada di Indonesia.
Sustainability of GUINÉ-BISSAU-Application of the action of Standards ISO 9001, 14001, 26000 and 45001
Authors: Baía Amândio Pereira , Silva Carla Correia 
Published: October 2023

Sustainability represents one of the greatest challenges of the millennium. Many countries have already implemented ISO standards on Management, Quality, Environment and Occupational Safety and Health systems. In Guinea-Bissau, the poor quality of management, forest deforestation, the extinction of several species of fauna and flora, the difficulties of collecting and treating waste, the non-compliance by companies with occupational safety and health standards, and the lack of business ethics in the process of operationalizing the activities of companies, aroused the interest in showing the relevance of the implementation of ISO standards - Quality Management (9001), Environment (14001), Safety and Health at Work (45001) and Social Responsibility (26000) in this country. The implementation of ISO standards in Guinea-Bissau will oblige organizations to comply with quality standards that will contribute to the improvement of the quality of life of Guineans and the sustainability of the planet.
Being Wholly Here and Partially There: John Buridan vs Nicole Oresme on the Soul’s Presence in the Body
Authors: Roudaut Sylvain 
Published: October 2023

Abstract
This paper studies the theories defended by John Buridan and Nicole Oresme on the presence of the soul in the body, with a special focus on the interpretation of the Augustinian principle – or ‘holenmeric’ principle – according to which the soul is in the whole body and is wholly present in every part of it. The first part of the paper introduces the different types of composition involved in the medieval discussions over the soul and its parts and shows how different psychological theories prior to 1350 employed this typology of part/whole relations to clarify the soul’s presence in the body. The next part of the paper presents how the theories designed by John Buridan and Nicole Oresme were motivated by problems raised by these earlier accounts of the soul’s presence and undertook to solve them from the perspective of a reductionist conception of parthood. It is argued that, despite their common commitment to a reductionist stance, the solutions endorsed by Buridan and Oresme represent two opposite ways of applying a nominalist metaphysics of parts to psychological matters.
Mündlichkeitsphänomene in der gesprochenen Wissenschaftssprache: Korpuslinguistische Befunde und didaktische Perspektiven
Authors: Schwendemann Matthias , Wallner Franziska 
Published: October 2023

Zusammenfassung
Der Beitrag untersucht Mündlichkeit in wissenschaftlichen Vorträgen von Sprecherinnen und Sprechern mit Deutsch als L1 aus dem GeWiss-Korpus und vergleicht diese mit Interaktionsdomänen aus dem Forschungs- und Lehrkorpus Gesprochenes Deutsch (FOLK). Zudem werden ausgewählte Mündlichkeitsphänomene (Abweichungen von der Standardlautung und die Verwendung von Modalpartikeln) in wissenschaftlichen Vorträgen analysiert.
Gendersensible Grammatik: Vorschläge zur Vermittlung von Genus und Personenbezeichnungen
Authors: Lipsky Angela 
Published: October 2023

Zusammenfassung
Die Autorin möchte zeigen, wie verschiedene für die Personenreferenz relevante Grammatikthemen im DaF/DaZ-Unterricht so dargestellt und vermittelt werden können, dass die Rolle von Genus beim Verweis auf Geschlecht (Sexus) und auf Gendervorstellungen deutlich wird. Ziel einer hier als gendersensibel bezeichneten Grammatikvermittlung soll es sein, Deutschlernende an aktuell diskutierte Aspekte gendergerechter Sprache heranzuführen und sie in die Lage zu versetzen, eigene Formulierungsstrategien zu entwickeln.
Strengthening Food Systems Resilience Before, During and After Disasters and Other Crises
Authors: Ryan Benjamin J. , Telford Victoria , Brickhouse Mark , Acosta Jose , Allen Cara , Bhatia Sanjaya , Campbell Jacqueline , Crowe Connor , Everrett Jeremy , Fendt Matthew , Fink Rok , Hatch Kristy , Hatch Tim , Johnson Aaron , Jones Reiley , Kanitz Lori A. , Knapp Landon , Krey Kathy , Larson Grant , McKone Joshua , Santa Cruz Andrea , Sandifer Paul A. , Brooks Bryan W. 
Published: October 2023

Abstract
School closures during the COVID-19 pandemic compromised access to essential meals for many children. In response, a public/private partnership known as the Emergency Meals-to-You program was established to deliver meals in affected rural areas of the United States. This study builds on this using a scorecard approach adapted from the United Nations Ten Essentials for Making Cities Resilient to identify and prioritize actions for strengthening food system resilience. A pilot food system resilience scorecard facilitated data collection from five workshops with professionals familiar with the program, emergency management, public health, or food systems. Data analysis and interpretation identified nine priority actions. These included integrating the food sector and schools within emergency management, mapping local food sector capacities, working with schools to receive de-identified data about nutritional, allergy and other health needs, developing disaster plans for sustaining food access at the school district level, and protecting ecosystem services and agricultural areas. There is an urgent need to embed the food sector and schools within emergency management. These systems are local, designed to coordinate complicated tasks in crises, multidisciplinary, and are used in many countries. Providing a ready-made framework for locally driven initiatives to strengthen food systems now and into the future.
Manipulation on radiation angles via spatially organized multipoles with vertical split-ring resonators
Authors: Tsai Hao-Yuan , Chen Che-Chin , Chen Chun-Yen , Lin Yi-Jie , Chen Wei-Chun , Chen Hung-Pin , Lin Yu-Wei , Tanaka Takuo , Yen Ta-Jen 
Published: October 2023

Abstract
Herein, the radiation patterns of single-split ring resonators (SSRRs) and double-split ring resonators (DSRRs) in the vertical direction are tailored by reconfiguring the resonator geometries. To design unequal arm lengths for controlling the floating split angle of the resonators and changing their electromagnetic multipole compositions, vertical metamaterials were fabricated using the metal-stress-driven self-folding method. The simulation results well agree with the experimental transmittance and reflectance results and demonstrate the geometry-dependent angle variation of the far-field radiation. Symmetric SSRRs and DSRRs radiate in the vertical and horizontal directions, respectively. With increasing pad shift, the radiation angle of the asymmetric SSRR completely rotates toward the horizontal direction along the ring plane, but the DSRRs can rotate only from 0° to 45° to the horizontal plane. Furthermore, by decomposing the multipoles into their constituents, we show that the directional scattering performance can be verified by manipulating the horizontal and vertical components of the electric dipoles. This novel combination of SSRRs and DSRRs can effectively and efficiently reconfigure the radiation direction in the infrared (IR) region, paving the way for color routers, metasurfaces, and directive IR emitters in compact optical metadevices.
Portfolio selection based on Extended Gini Shortfall risk measures
Authors: Ben Hssain Lhoucine , Berkhouch Mohammed , Lakhnati Ghizlane 
Published: October 2023

Abstract
In this paper, we conducted a comprehensive examination of the Extended Gini Shortfall (EGS) as a flexible risk measure for portfolio selection, employing various approaches.
The EGS measure possesses desirable properties, such as coherence, risk and variability measurement, and risk aversion.
Additionally, we introduced the Reward Risk Ratio induced from EGS and explored its associated properties.
Our main focus centered on a convex optimization problem, where the objective was to minimize portfolio risk while adhering to reward and budget constraints.
We demonstrated the effectiveness of the obtained theoretical results through a practical application.
Midkine can not be accepted as a new biomarker for unexplained female infertility
Authors: Ergüven Mine , Kahraman Semra , Pirkevi Caroline , İrez Tülay 
Published: October 2023

Abstract

Objectives
This study aimed to investigate whether a growth factor and a cytokine midkine (MK) can be a new biomarker for the diagnosis and treatment of unexplained female infertility (UFI) cases.

Methods
Serum (S), follicle fluid (FF), and cumulus cells (CCs) of the patients aged 20–42 years, diagnosed with male factor (MF) and UFI were used. Patients underwent Intracytoplasmic Sperm Injection (ICSI). The anti-Müllerian hormone (AMH) and MK levels with other hormone levels (FSH, LH, E2, PRL, INHB, TSH), the oocyte and embryo qualities, the fertilization and pregnancy rates, and cumulus cells (Cell number and ultrastructure, apoptosis rate) were evaluated. Student-T-test was performed and p<0.05 was considered statistically significant.

Results
The lowest numbers of CCs were found at UFI (p<0.05). The lowest apoptosis rate with the highest CC viability rate was evaluated at MF (p<0.05). The lowest AMH and MK levels (S, FF) were detected at UFI in comparison to MF (p<0.05). MK and AMH levels of non-pregnant subjects were much lower than pregnant subjects (p<0.05). In addition, these levels were lower in the subjects above 35 age (p<0.05). Structural analysis of CCs showed that the number of lytic cells with cell remnants and apoptotic bodies was higher in non-pregnant subjects. It seems that MK did not show any resistance to both AMH and apoptosis.

Conclusions
MK can not be accepted as a new biomarker for the diagnosis and treatment monitoring of UFI cases.