bluuebunny/crossref_metadata_2025_split huggingface dataset:
Digital Pathology in the Detection of Infectious Microorganisms: An Evaluation of Its Strengths and Weaknesses Across a Panel of Immunohistochemical and Histochemical Stains Routinely Used in Diagnostic Surgical Pathology
Authors: Haghighi Mehrvash , Bryce Clare , Paulsen John D. , Hussein Shafinaz , Veremis Brandon , Salib Christian , Alialy Roshanak , Lahori Mega , Hao Yansheng , Liang Yuanxin , Szporn Arnold , Westra William 
Published: February 2024

Context.—
The diagnosis of some infectious diseases requires their identification in tissue specimens. As institutions adopt digital pathology for primary diagnosis, the limits of microorganism detection from digital images must be delineated.

Objective.—
To assess the reliability of microorganism detection from digitized images of histochemical and immunohistochemical stains commonly used in pathology.

Design.—
Original glass slides from 620 surgical pathology cases evaluated for the presence of infectious microorganisms were digitized. Immunohistochemical stains included those for herpes simplex virus (n = 100), cytomegalovirus (n = 100), Helicobacter pylori (n = 100), and spirochetes (n = 80). Histochemical stains included mucicarmine for Cryptococcus spp (n = 20), Grocott methenamine silver for fungi (n = 100), Giemsa for H pylori (n = 100), and Ziehl-Neelsen for acid-fast bacilli (n = 20). The original diagnosis based on the glass slides was regarded as the reference standard. Six pathologists reviewed the digital images.

Results.—
Digital review was generally associated with high (ie, ≥90%) specificity and positive predictive value owing to a low percentage of false-positive reads, whereas a high percentage of false negatives contributed to low sensitivity and negative predictive value for many stains. Fleiss κ showed substantial interobserver agreement in the interpretation of Grocott methenamine silver and immunostains for herpes simplex virus, H pylori, and cytomegalovirus; moderate agreement for spirochete, Ziehl-Neelsen, and mucicarmine; and poor agreement for Giemsa.

Conclusions.—
Digital immunohistochemistry generally outperforms histochemical stains for microorganism detection. Digital interpretation of Ziehl-Neelsen and mucicarmine stains is associated with low scores for interrater reliability, accuracy, sensitivity, and negative predictive value such that it should not substitute for conventional review of glass slides.
ENGELLİLİK PERSPEKTİFİNDE İSKANDİNAV ÜLKELERİ: DANİMARKA VE İSVEÇ'TE ENGELLİLERE YÖNELİK YASAL DÜZENLEMELERİN KARŞILAŞTIRILMASI
Authors: SÖZEN Hilmi 
Published: February 2024

Engelli kişilerin esenliği, kişisel ve toplumsal önemi olan bir konudur. Bu kişilerin yaşam kalitesinin yükseltilmesi için, ülkelerin yasal düzenlemeler yapması ve engelli haklarını güvence altına alması büyük önem taşımaktadır. Bu araştırma, farklı refah rejimlerine sahip iki İskandinav ülkesine, Danimarka ve İsveç'e odaklanmaktadır. Her iki ülke çerçevesinde; ayrımcılık ve eşitlik, erişilebilirlik, istihdam, eğitim, sağlık hizmetleri, bakım hizmetleri, barınma/konut desteği, sosyal hizmetler vb. konulara ilişkin yasal düzenlemeler gözden geçirilmiştir.
Çalışmanın temel amacı, Danimarka ve İsveç'te yaşayan engelli bireylerin yaşam kaliteleri/standartları ile sosyal hayata aktif katılımlarına yönelik yasal düzenlemelerin benzerliklerini ve farklılıklarını ortaya koymaktır. Araştırma yönteminde, nitel araştırma alanında literatür taraması yaklaşımı kullanılmıştır. Veriler, ilgili kanunlar, politika belgeleri ve resmi kaynaklar kullanılarak, söz konusu ülkelerde engellilere ilişkin yasal düzenlemeler ayrıntılı bir şekilde incelenmiş ve karşılaştırılmıştır. Çalışma sonucunda, her iki ülkenin de engelli bireylerin refah düzeyinin yükseltilmesine yönelik yasal düzenlemelerin içeriği konusunda benzer yaklaşımlar izlediği, ancak bazı farklılıkların da olduğu tespit edilmiştir Bu iki ülkenin karşılaştırılması, diğer İskandinav ülkeleri için engellilik politikasının geliştirilmesine ışık tutmaktadır.
Formación docente e inclusión educativa: un estudio comparado en Italia y España
Authors: Nistal Anta Verónica , López-Aguado Mercedes , Gutiérrez-Provecho. Lourdes 
Published: February 2024

La inclusión educativa está incluida en las políticas de muchos países europeos, entre ellos, Italia y España. Este estudio tiene como objetivo
conocer y comparar los sistemas educativos de ambos países
en relación a la educación inclusiva. Asimismo, se pretende analizar la organización escolar para la atención del alumnado con necesidades educativas especiales y la formación inicial del profesorado en inclusión educativa en la educación superior universitaria. Para ello, se siguen las fases propias del método de Educación Comparada. Se emplea el análisis documental como herramienta para la extracción de datos. Se examinan diversas categorías organizadas de manera jerárquica. Los resultados indican diferencias significativas en la atención al alumnado con necesidades educativas especiales en ambos países destacando como indicador comparativo la modalidad de escolarización. Asimismo, se observa que el concepto de necesidades educativas especiales no es el mismo, lo que puede suponer una atención diferente para el alumnado y, por lo tanto, una intervención educativa más inclusiva en un país que en otro. Se resalta la importancia de la formación inicial y permanente del profesorado para la atención de este tipo de alumnado priorizando contenidos inclusivos dentro de los planes de estudio de las universidades. Esta investigación sugiere la eliminación del tradicional modelo dual de separación entre el docente curricular y el docente especializado de apoyo ya que parece ser inadecuado para representar una realidad educativa inclusiva
EVALUACIÓN DEL DESEMPEÑO DOCENTE A TRAVÉS DE LA HETEROEVALUACIÓN EN EL ISU CARLOS CISNEROS
Authors: Guaño Alvarez Ana Cristina , Montalvo Armijos Renny Geovanny , Zabala Barragan Leticia Aurelina , Alvarado Cadena Jorge Roberto 
Published: February 2024

Heteroevaluación es una estrategia que busca evaluar el desempeño de los docentes por parte de colegas, autoridades y estudiantes de manera objetiva y sistemática. Los resultados obtenidos en la presente investigación, se destaca que, en promedio, la evaluación docente se sitúa en torno al 94.81%, indicando una tendencia general positiva en el desempeño docente. Sin embargo, se observan fluctuaciones a lo largo de los diferentes períodos académicos, con picos de excelencia que alcanzan el 96.85% y niveles más bajos alrededor del 88.72%, tomando como valoración una nota equivalente a muy buena, aun estando en el nivel más bajo.

El estudio se enfoca en tres áreas principales de la heteroevaluación: "Evaluación," "Pedagogía y Conocimiento," y "Relaciones Humanas y Atención al Estudiante." En "Evaluación," se observa que, a pesar de un rendimiento positivo, este aspecto tiende a tener calificaciones más bajas en comparación con los otros dos ámbitos evaluados. No obstante, se destaca un aumento significativo durante el período de diciembre de 2021 a abril de 2022. En "Pedagogía y Conocimiento," se registra una valoración del 95%, con fluctuaciones a lo largo de los períodos académicos. Por último, en "Relaciones Humanas y Atención al Estudiante," se valora con el 95.47%, con máximos y mínimos en diferentes momentos, por lo tanto, nos indica que, las labores realizadas por los docentes están muy bien valorada por quienes realizaron la evaluación.
ANÁLISIS DEL DISEÑO DE LAS OREJAS DE IZAJE DE UN AUTOTANQUE DE 8000 GALONES, APLICANDO ELEMENTOS FINITOS MEDIANTE SOFTWARE CAE
Authors: Villa Orozco Mariana Elizabeth , Bermeo Jiménez Byron Hernán , Bermeo Jiménez Verónica Vanessa , Chimborazo Aucanshela Ángel Antonio 
Published: February 2024

El objetivo del presente estudio es analizar el diseño de las orejas de izaje de un autotanque de 8000 galones para transporte de GLP, aplicando normas ASME, y elementos finitos mediante dos softwares CAE (Computer-Aided Engineering) PrePoMax y Ansys Student, para evaluar la resistencia, la rigidez y el factor de seguridad y realizar una comparación con investigaciones precedentes.
Se determina la masa del autotanque en vacío con sus accesorios igual a m = 11598.95 kg, que soportará las orejas durante las operaciones de izaje. Con este valor se diseña determinando sus dimensiones y posteriormente se modela utilizando un software CAD. Esto incluye definir las dimensiones, geometría y detalles de construcción. Se procede a validar el diseño mediante los softwares CAE. Se establece: la geometría, el material SA516-70, mallado, las cargas a un ángulo máximo de α = 45° recomendado por la norma ASME, W1x = 40229.32 N, W1y = 40229.32 N y condiciones de borde. Se refina la malla para obtener buenos resultados considerando que el gasto computacional es directamente proporcional a la calidad de resultados.
En los dos programas se obtuvieron: desplazamientos máximos aproximadamente de ∂max = 0.02mm, esfuerzos equivalentes máximos según Von Misses de σmax = 56.24 MPa, y factor de seguridad mínimo de nmin = 4.41. La diferencia de los resultados obtenidos en los programas de simulación es mínima en 0.57%. Los resultados obtenidos según la colorimetría coinciden que la zona critica es la superficie interna de la oreja. Según el factor de seguridad obtenido da un margen de seguridad de más del 300% garantizando el funcionamiento adecuado.
Al realizar la comparación de los resultados obtenidos con otra investigación la diferencia más relevante está en el factor de seguridad aproximadamente del 58%; esto se debe a las consideraciones establecidas en cada estudio.
Sacral Art of the Roman Catholic Church in Ukraine under Scientific Research (1993-2021)
Authors: Demianchuk Andrii , Hrymskyy Vladyslav , Tsyhanyk Myroslava , Tymkiv Bohdan , Pidkova Ihor 
Published: February 2024

The aim of this study is to review the multi-volume scientific publications and monographs (single and collective) from 1993-2021 that examine the sacred art of the Roman Catholic Church in Ukrainian territories. The methodology and specifics of the main works are clarified, and problematic issues and difficulties encountered by researchers during their work are identified. Methodology. The study employs an integrated approach that utilises scientific analysis methods such as systematisation and generalisation. It also combines historical, cultural, art historical, and theological methods. This approach is appropriate, considering the liturgical purpose of sacred art and the requirements set by the Catholic Church based on the Holy Scriptures. Research results. A review of scientific works in multi-volume publications, as well as individual monographs, suggests that the sacred art of the Roman Catholic Church in Western Ukraine was formed over many centuries. Researchers have studied over 500 shrines and tens of thousands of liturgical items of significant historical, cultural, and artistic value. Renowned scholars, including Jan K. Ostrowski, A. Betlej, T. Zaucha, K. Brzezina, P. Krasny, R. Quirini-Poplawski, J. Petrus, S. Lenartowicz, M. Biernat, M. Walczak, J. Skrabski, M. Kurzej, R. Nesteruw, T. Kukiz, and others (Polish edition), M. Buchek, I. Sedelnyk (Polish, Ukrainian edition), D. Antoniuk (Ukrainian edition), and others, conducted a comprehensive study, inventory, and attribution of these monuments. Scientific novelty. The obtained results highlight the challenges of studying sacred art monuments in Ukraine during the specified period. The specifics and methodology used by Ukrainian and foreign scholars in scientific research are identified through multi-volume scientific publications and monographs (individual and collective). Recommendations. Further historical, cultural, and art historical research is required to complement previous publications and enhance our understanding of the specifics of sacred art, particularly painting. This research will also reveal the methodology and technology used in creating these monuments. It is crucial to preserve these sacred monuments from destruction, especially during the period of military invasion by the Russian Federation since 24 February 2022.
MANAGING CHALLENGES AT MLNG SATU DISTILLATION COLUMNS
Authors: A Kaher Izyan Farhana , Che Din Nazatul Sheema 
Published: February 2024

To realise the ultimate operating potential of distillation columns via maximising the yield throughput without compromising product quality at lower operating costs has always been an aspiration for Malaysia LNG Sdn Bhd (MLNG Satu). Existing Advanced Process Control (APC) has been helping the plant to deliver better process stability at the Fractionation Unit. Operating high-purity distillation columns in MLNG Satu imposes a challenge to APC control because of its non-linear and intensely interactive dynamics. In addition, frequent changes in feed compositions and feed flow must be dealt in a continuous basis, which failed to do so will results in a significant upset in the product compositions. The distillation process is also known to utilise a large amount of energy, which can significantly influence the overall plant profitability. Realising energy optimisation has a significant contribution towards overall operational costs in distillation columns’ operation. Therefore this has become a prime target when performing APC revamp that recently took place at MLNG Satu (De-ethaniser, De-propaniser, De-butaniser column). This abstract describes the challenges and implementing control strategies to establish a disturbance feedforward model, minimise energy consumption and maintain optimum product impurity. Although distillation processes are inherently non-linear, a process control system based on linear input-output model can be acquired if operated over a sufficiently small region. Hence, a linear multivariable predictive control is developed, provides multiobjective control handling based on objective hierarchy. The applied control strategy has successfully improvised the dynamic control performance, resulting in a reduction in product quality variability, increment in product yield, and minimisation of the unit operating cost. It is expected to bring more value as the APC controller uptime increases over time. Intangibly, the competency of plant operators in dealing with advanced technology, i.e., APC, to optimise plant operation, has been enhanced from control to supervisory role, allowing for overall plant optimisation to be done in minute intervals.
Keywords: Advanced Process Control (APC), Non-Linear, Distillation Columns
REALISING OPTIMAL ENERGY CONSUMPTION VIA ENHANCED iCON® UTILITY OPTIMISER (iUO 2.0)
Authors: Mohd Khairil Hing Azleen Azna , Muhd Ali Fadzrul Izwan 
Published: February 2024

iCON® utility optimiser (iUO) was first introduced in PETRONAS in 2010, and it has been extensively utilised in energy review studies across PETRONAS’ downstream processing plants. The tool is the first in PETRONAS to use the first principal steady-state simulation with customised unit operations to perform mass and energy balance of a steam plant. An enhanced version of the optimiser, iUO 2.0, was released in 2019, offering much-improved robustness, accuracy, and flexibility. The software enhancements focused on three objectives: increased robustness, improved accuracy, and enhanced applications. Greater robustness and speed are achieved by auto-generating the property package and the migration from source original point (SOP) objects to script-based unit operations. Accuracy is enhanced by offering more specification handles for the user to benchmark against the actual operation. These include specifications for efficiency, energy loss, heat rate with a correction factor, compression/expansion ratio, vendor performance customisation for GTG, and a sectionalised section for boiler and HRSG. Enhanced applications of the unit operations include linking to historian data and plant monitoring of the specific equipment for modelled variables such as equipment efficiency. Efficient and timely utility equipment monitoring will allow improved productivity and operational efficiencies at the site. Plantwide steam network modelling allows a structured review of optimisation opportunities of the steam network system as a whole. The enhancements in iUO 2.0 promise a better realisation of the targeted benefit from desktop modelling to site implementation; and improve its readiness for future digital transformation and implementations. This paper showcases 3 example applications of iUO 2.0 using a gas turbine, HRSG, and a plantwide example case to demonstrate the robustness and opportunity evaluation for a utility plant optimisation.
Keywords: Simulation, modelling, steam system, industrial application, energy
Finite Element Simulation of Forward Extrusion of Copper produced by Equal Channel Angular Pressing
Authors:   University of Zawiya, Agena Ahmed.S.M 
Published: February 2024

In this paper, a simulation study of the forward extrusion process of three types of copper metal produced from the ECAP process was studied. A rolling operation was conducted on two of them, and they are as follows: 1-	A commercial high purity Cu (99.99%) rod of 10 mm in diameter was processed using the equal channel angular pressing (ECAP) method. This metal was named as (ECAP – Cu). 2-	ECAP Cu subjected to a 1180 % cold rolling at the liquid nitrogen temperature (LNT). This metal was named as (ECAP Cu + 1200-LNT). 3-	ECAP Cu subjected to a 1340 % cold rolling at the liquid nitrogen temperature (LNT), and this metal was named as (ECAP Cu + 1350-LNT). The true stress true strain of the three metals were calculated and entered into the simulation program to calculate: extrusion load, flow stress and equivalent strain for the three metals when extruded into dies with extrusion channels having lengths of 3 mm, 6 mm, and 9 mm. With a proven percentage of reducing in the extrusion process from a diameter of 16 mm to a diameter of 10 mm. From practical experiments conducted on copper metal, it was noted that: •	Its mechanical properties have changed and it has a high strength, as well as the amount of yield stress has increased •	The greater the percentage of shortening in the rolling process, the greater the yield stress. •	From the simulation process, it was found that the values of the extrusion load, the equivalent strain, and the flow stress have changed and increased
MENGATASI KESULITAN BELAJAR DENGAN MODEL DESAIN PEMBELAJARAN ASSURE BERBASIS MULTIMEDIA
Authors: Sein Lau Han , Nurul Atik Hamida  , Andy Litehua  
Published: February 2024

ABSTRAK
Implementasi Model Desain Pembelajaran ASSURE Berbasis Multimedia Pada Materi Fiqh Sebagai Upaya Mengatasi Kesulitan Belajar Peserta didik. Tujuan dari penelitian ini adalah untuk mengetahui penerapan model desain pembelajaran ASSURE berbasis multimedia pada materi Fiqh sebagai upaya dalam mengatasi kesulitan belajar peserta didik di MI Darul Ulum Madiun. Penelitian ini merupakan jenis penelitian kualitatif dengan menggunakan analisis deskriptif, teknik pengumpulan data dalam penelitian ini menggunakan observasi, wawancara dan juga dokumentasi. Hasil penelitian ini menunjukkan bahwa penggunaan model Assure berbasis multimedia pada materi fiqh ini dapat menjadi alternative pembelajaran dan sebagai upaya dalam mengatasi kesulitan belajar peserta didik, dengan menganalisis karakteristik peserta didik, gaya belajar, pemilihan metode, media dan bahan ajar yang sesuai, serta melibatkan peserta didik secara aktif dalam pembelajaran sehingga dapat mengurangi kesulitan belajar peserta didik.
Early Blood Gas Analysis in SARS-COV-2 Infected Patients Admitted to SMHS Hospital: A Tertiary Care Hospital in Kashmir
Authors: Farooq Iqra , Eachkoti Rafiqa , Mohiuddin Amir , Majid Sabhiya 
Published: February 2024

Inroduction: Blood gases are a measurement of how much oxygen and carbon dioxide is in blood. These determine the acidity of blood. The blood gas testing is generally used for detecting and monitoring lung and kidney problems. The blood gas testing measures partial pressure of oxygen (o2), partial pressure of carbon dioxide (CO2),oxygen saturation(O2Sat), bicarbonate(HCO3) concentration .
Materials and Methods: Here in study Patients aged more than 18 years confirmed Covid 19 positive by reverse transcription, PCR (RT-PCR). Patients suffering from moderate to severe Covid 19 as per WHO diagnostic guidelines and underwent at least one ABG were included in the analysis. The ABG test was done on ABG analyzer in department of Biochemistry, SMHS hospital. All the data which was related to study was gathered and recorded in case record forms using files. As well as reports of patients from medical record section.
Results: Alkaline pH was found in 57.33% individuals.36% individuals were having normal pH and the percentage of individuals having acidic pH was 6.66%. Low PaO2 was found in 45.33% individuals. Normal PaO2 levels were found in 21.33% and high PaO2 levels were found in 33.33% individuals .Low PaCO2 (<35 mmHg) were found in 56%, normal (35-45mmHg) levels were found in 37.33% and high levels (>45mmHg) were found in 6.66%. Low HCO3- (<22mmol/L) were found in 16%, normal (22-26mmol/L) in 38.66% individuals and high (>26mmol/L) were found in 45.33% individuals would be expected in the case of respiratory alkalosis.
Conclusion: Regular ABG monitoring can aid in the early detection of silent hypoxia, and respiratory injury. With early management start-up, many lives can be spared with early diagnosis.
Effects of Climate and Weeds on the Establishment of Thyme-Based Living Mulch Systems in Drylands of Cyprus
Authors: Matsi Sofia , Sarris Dimitrios , Konstantinou Maria 
Published: February 2024

Backround: Mulching systems are at the spotlight of sustainable soil management as nature-based solutions for combating desertification.
Aims: We tested how living mulch systems based on rainfed Thymbra capitata [(L.) Cav.], can be established under different pressure from drought and weeds in dryland carob plantations.
Study design: 10 thyme plots in semi-arid climate (SKR); 11 plots in arid climate (VRY); different weed competition intensity (60 thymes per plot).
Place and Duration of the Study: South-eastern Cyprus, between December 2019 and 2022.
Methodology: Survival and soil cover for 1260 T. capitata seedlings (3-5 cm tall, 16 seedlings per m2) was assessed at the end of 3 dry seasons (d.s.) together with weed community composition, weed abundance (w.a.) and biomass. Climate data and De Martone’s Aridity Index (DMAI) were used to assess drought severity.
Results: Around 80% of the thymes survived at the end of the first d.s, that followed a very rainy year (ca. 600 mm annual precipitation; P; ca. +50% than normal; ca. 19 DMAI). Thyme survival appeared unaffected by w.a. in both sites. After a severe drought that occurred the second year (ca. 300 mm P; ca. -22% than normal; ca. 9.5 DMAI) thyme survival rates dropped at the end of the d.s. to ca. 20% at the site with 3 times higher w.a./ biomass (mostly from Avena sp.). However, they were unaffected under low w.a. creating a 29% soil cover (vs.7% in VRY). These results remained till the end of the third d.s.
Conclusions: To combat desertification and drought intensification under climatic change, rainfed T. capitata as living mulch appears unaffected by weeds during wet years, or in very dry years under low w.a. However, under high w.a., a weed management system is required if climate is arid.