bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bringing the Politics of Climate Change Down to Earth: Student Descriptions of Dwelling Place and “Geo-Graphies” as Alternative Belongings
Authors: Jeong Sophia , Silverman Elena H. 
Published: November 2023

Purpose This study draws on Bruno Latour's work, Down to Earth: Politics in the New Climatic Regime, to re-imagine issues of climate change in K-12 science teaching and learning. “Re-turning” to a dwelling place can become an investigation, while issues of gender, race, education, food, technology, and religion can be elicited in relation to climate change issues. This allows students to be able to map a political “geo-graphy” that would be meaningful and matter to them. Design/Approach/Methods We apply Latour's concepts of dwelling place and geo-graphies in the teaching and learning of climate change in the secondary science classroom. Our Latourian inquiry questioned, “How do students’ up-close and local-level descriptions of their dwelling place create geo-graphies that foster their understanding of the shared, inhabitable Earth and imagine an alternative way of belonging to the Earth?” Findings By re-orienting students’ thinking to be more inclusive about who has the capacity to act, we aim to make the issues of climate change local and relevant in students’ everyday lives. Originality/Value We respond to Latour's call to conceive of alternative ways of belonging to and inhabiting this world that are more ethical and responsible.
Alternative Conceptions About Climate Change in a Group of Teachers in Chile: Are Science Teachers More Knowledgeable Than Non-Science Teachers?
Authors: Abasto Verónica , Larraín Antonia , Vergara Claudia , Cofré Hernán 
Published: November 2023

Purpose This study aimed to describe the knowledge and alternative conceptions of climate change in a group of Chilean science and non-science teachers with different teaching experiences. Design/Approach/Methods The study used a quantitative approach with an exploratory, descriptive, and transversal design, in which a Climate Change Questionnaire was applied to a group of 64 pre-service and in-service teachers. Findings The results demonstrated that the whole group of teachers had moderate knowledge about climate change, presenting some alternative conceptions, such as confusion about greenhouse gases, solar radiation, and the false relationship between ozone layer thinning and the greenhouse effect. There was no difference in climate change knowledge between science and non-science teachers or among teachers with different teaching experiences. Originality/Value This is the first research work published in an international journal on the knowledge of climate change by a group of teachers in Chile (and Latin America); therefore, it is an original contribution to the literature about climate change education. Furthermore, we tested hypotheses regarding the effects of experience and scientific background on teachers’ knowledge of climate change.
Clinical Utility of an AI-powered, Handheld Elastic Scattering Spectroscopy Device on the Diagnosis and Management of Skin Cancer by Primary Care Physicians
Authors: Jaklitsch Erik , Thames Todd , de Campos Silva Thomaz , Coll Patrick , Oliviero Margaret , Ferris Laura Korb 
Published: November 2023

Background: Patients with lesions suspicious for skin cancer often present to primary care physicians (PCPs), who may have limited training in skin cancer diagnosis. Objective: To measure the impact of an adjunctive handheld device for PCPs that employs elastic scattering spectroscopy (ESS) on the diagnosis and management of skin cancer. Methods: Fifty-seven PCPs evaluated 50 clinical images of skin lesions (25 malignant and 25 benign), first without and then with knowledge of the handheld ESS device output, and in each case indicated if a lesion was likely to be benign or malignant. Results: The diagnostic sensitivity of the PCPs with and without the use of the ESS device was 88% (95% CI, 84%-92%) and 67% (95% CI, 62%-72%), respectively ( P < .0001). In contrast, no significant difference was observed in the diagnostic specificity. The management sensitivity of the physicians with and without the use of the ESS device was 94% (95% CI, 91%-96%) and 81% (95% CI, 77%-85%), respectively ( P = .0009). Similarly, no significant difference was observed in the management specificity. Conclusion: The use of the ESS device may have the potential to help improve skin cancer diagnosis and confidence in management decision-making in a primary care setting.
Implementation of Antimicrobial Stewardship Interventions in Primary Care: Acute Bacterial Rhinosinusitis Treatment Strategies
Authors: Meier Mackenzi , Pierce Kristen , Musgrove Rachel , Holmes Zachary , Harris Akeia , Veronica Asuquo Ndifreke , Macias-Moriarity Lilia Z. , Woodhouse Ashley 
Published: November 2023

Background: The highest prescribing rates for antibiotics occur in primary care, therefore, ambulatory care pharmacist interventions could play a major role in preventing overuse and misuse of antibiotics. Delegated pharmacists in the SJC primary care setting guided 3 activities with a goal of positively impacting prescribing patterns: monthly webinars provided by Agency for Healthcare Research and Quality (AHRQ), quarterly reporting to physicians of antibiotic prescribing patterns, and development of a clinical decision-making support tool for antibiotic prescribing. Methods: Retrospective, observational data was collected to evaluate antibiotic prescribing patterns in patients diagnosed with acute sinusitis both before initiatives were implemented (July 1, 2019 through June 30, 2020) and after the initiatives were implemented (April 1, 2022 through June 30, 2022). Results: A total of 675 patients were diagnosed with acute bacterial sinusitis during the specified time frame. Of these, 138 patients were excluded. A total of 279 antibiotics were prescribed in the preintervention group out of 298 patient encounters (93.6%) and 225 antibiotics were prescribed in the post-intervention group out of 244 patient encounters (92.9%) ( p = .26). Although the primary outcome was not statistically significant, a significant reduction in patients treated with fluoroquinolones was noted, with 59/298 (20%) of those being prescribed in the pre-intervention group and 20/244 (8%) in the post intervention group ( P = .02). Conclusions: While pharmacist-led antimicrobial stewardship interventions in primary care did not result in a decrease in the overall prescription of antibiotics for acute sinusitis, our study did reveal a notable reduction in the use of fluoroquinolones. This finding highlights a promising avenue for expanding the role of ambulatory care pharmacists.
Associations between small-area sociodemographic characteristics and intimate partner violence in Montréal, Québec
Authors: Rodrigues Paul , Fernet Mylène , Cousineau Marie-Marthe , Philibert Mathieu 
Published: November 2023

Background: Intimate partner violence (IPV) affects many individuals and can have a significant impact on their health and well-being. In order to inform prevention strategies, several studies have focused on the determinants of IPV. However, knowledge on the association between neighbourhood characteristics and IPV remains scarce. The social disorganization theory posits that certain neighbourhood characteristics are associated with violent behaviours. This theory has been used to explain spatial variations in IPV, but most studies have been conducted in the United States. Little is known about the effect of neighbourhood factors in urban contexts outside of the United States. Design and methods: Using police data from 2016 and 2017, this study estimated the association between sociodemographic characteristics of neighbourhoods (socioeconomic status, single-parenthood, residential instability and ethnocultural heterogeneity) and IPV victimization in Montréal, Québec. Results: Results suggest a neighbourhood-level variation in IPV, and that neighbourhood-level characteristics are associated with IPV victimization. Specifically, the likelihood of IPV is higher in neighbourhoods with the lowest SES level (OR = 2.80, 95%CI: 2.47–3.17, p < 0.001) and the lowest level of residential instability (OR = 0.81, 95%CI: 0.70–0.93, p = 0.003) as well as the highest proportion of single-parent households (OR = 1.88, 95%CI: 1.65–2.15, p < 0.001). Conclusion: Although neighbourhood-level interventions to reduce IPV are rare, our results highlight the importance of developing such preventive strategies. Prevention programs targeting high-risk neighbourhoods may prove effective in reducing IPV.
Managing in Critical Care Settings: A Qualitative Study of South African Nurse Unit Managers and the Psychological Contract
Authors: Ronnie Linda 
Published: November 2023

Introduction Little is written about the management of psychological contracts by nurse unit managers (NUMs) in critical care settings and how this perspective contributes to the performance, experiences, and views of nurses and nursing teams. Psychological contracts are important regulators of the employer–employee relationship, with managers (NUMs) being the embodiment of the employer in managing the contract. Objectives This qualitative study answers a call for research on the NUM perspective of the psychological contract given the role they play in the wellbeing of critical care nurses and quality of care provided. The study aims to understand the expectations and obligations that constitute the psychological contract NUMs have with their nursing teams, the nature of the contract, and how NUMs practically manage these aspects on their teams. Methods Using an interpretive qualitative research design and a purposive sampling technique, semi-structured interviews were conducted with 10 of the 14 NUMs from a public health facility about critical incidents relating to their obligations and expectations of managing critical care nurses. Results A thematic analysis of their responses revealed five main themes that represent the contents of their psychological contracts with critical care nurses: professional commitment and obligation; leading by example; trust and support; teamwork; and on-the-job training and further development. In their discussion of these components, the NUMs also revealed how they manage the psychological contract with nurses. Conclusion Based on the expectations and obligations NUMs hold with their staff, their psychological contracts were found to be largely relational, with elements of the balanced type, suggesting that they rely on interpersonal connection and coordination, as well as knowledge dissemination, to uphold the contract. This contract appears to be effective in inculcating the commitment of nurses to their profession and professional standards through the building of trust and offering of support. However, recommendations are offered to ensure NUMs are best prepared to sustain these psychological contracts and continue to support nurse wellbeing and related patient care.
The Epidemiology of Facial Injury on the Far Side of the COVID-19 Pandemic Curve: What Happened After the Repeal of Social Distancing Laws?
Authors: Hoffman Gary R. , Kelly Sophie K. M. , (Mark) Tsai Hao-Hsuan 
Published: November 2023

Background: In response to the COVID-19 outbreak, the widespread imposition of social distancing and lockdown orders had an unintended secondary effect on reducing and changing the characteristics of facial injury presentations to tertiary referral hospitals. As the pandemic curve plateaued and indeed fell, these restrictions were periodically repealed, engendering an anticipated rise in the frequency facial injuries. Objective: The purpose of this study was to determine whether the frequency and characteristics of facial injury presentations to our tertiary referral hospital returned to pre-COVID levels following the repeal of COVID-19 social distancing and lockdown laws on the far side of the pandemic curve. Methods: The authors designed and implemented a retrospective study of patients who sustained a facial injury over 3 comparable 8-week periods in 2019 (pre-COVID), 2020 (COVID lockdown) and 2023 (post-repeal of COVID lockdown laws). The study was conducted in the Department of Maxillofacial Surgery at a level 1 tertiary referral regional trauma hospital in Newcastle, Australia. Results: The principal finding was an increase in facial injury frequency in the post-COVID cohort (n = 149), compared to the COVID lockdown (n = 37) and pre-COVID groups (n = 103). Across all 3 periods, males consistently outnumbered females, with a common peak in the 20 to 30 age group. Bony injuries predominated in all cohorts, with no difference in management approach. The leading cause of injury pre-COVID was interpersonal violence, which shifted to falls during lockdown and post-COVID. There was also an increase in workplace and animal-related injuries post-COVID. Conclusion: The frequency and characteristics of facial injury presentation finally stabilized and returned to pre-COVID levels following the repeal of social distancing laws. This was most notable as communities entered the far side of the pandemic curve. The findings are in keeping with a very small number of comparable studies sourced from literature.
Success and Challenges of Community Bicycle Advocacy Organizations in Reaching Underserved Populations
Authors: Elliott Lucas D. , Bopp Melissa 
Published: November 2023

Introduction Bicycling, as forms of recreation and travel, offers many positive physical and mental health benefits, though there are still many disparities in bicycling rates among underserved populations in the United States. Community bicycling advocacy organizations/coalitions promote and advocate for increased bicycling; however, have been shown to have a lack of organizational capacity for equitable programming to diverse populations (racial/ethnic minorities, women, low-income, LGBTQ+ communities, youth). The purpose of this study was to understand the current practices for providing underserved populations bicycling programming among advocacy organizations and to find major barriers and helpful tools for equitable programming. Methods This was conducted in a volunteer sample of U.S. bicycle advocacy organizations. An interview ( n = 23) assessed organizational function, successful programs, and barriers to reaching underserved populations. Results Several themes emerged from the interviews. Participants stated that the lack of organizational leadership and member diversity, along with a lack of trust with underserved communities, presented major barriers to providing equitable programming. Partnering with other community organizations that place an emphasis on serving diverse populations was noted to have potential for increasing successful programming by allocating resources and connections. Conclusion Although barriers exist for bicycle advocacy organizations when attempting to reach underserved and diverse populations, groups should focus on creating successful and diverse partnerships to increase the capacity for providing equitable programming.
Exploring Leadership Communication Competencies, Within Health Care, That May Have Been Exacerbated by the Pandemic
Authors: Kallstrom Eric 
Published: November 2023

Objective: The aim was to explore the existence of health care leadership gaps in communication, which occurred during the COVID-19 pandemic, by utilizing a qualitative research approach. Materials and Methods: Participants were recruited from a single professional organization. The volunteer leadership group was the frame for recruiting study participation. This work was conducted with a flexible research design method. A demographic survey, interview guide, and data triangulation survey were used to collect data from 21 participants over a four-week period. The participant responses were then analyzed through a process of coding and thematic analysis. Results: Five themes were generated from this cohort’s data, which alluded to gaps in leadership communication. These gaps occurred in the leader/employee relationship, at their respective institutions. Triangulation of the data from surveys underscored the presence of these communication gaps. Conclusion: The findings of this study may suggest the importance of a set of communication competencies for those in health care leadership, regardless of the complexities of a pandemic.
Hybrid Bt cotton is failing in India: cautions for Africa
Authors: Gutierrez Andrew Paul , Kenmore Peter E. , Ponti Luigi 
Published: November 2023

AbstractThis paper reviews the ongoing failure of hybrid transgenic Bt (Bacillus thuringiensis) cotton unique to India. The underlying cause for this failure is the high cost of hybrid seed that imposes a suboptimal long-season low plant density system that limits yield potential and has associated elevated levels of late-season pests. Indian hybrid Bt cotton production is further complicated by the development of resistance to Bt toxins in the key pest, the native pink bollworm (Pectinophora gossypiella Saunders, PBW), resulting in increased insecticide use that induces ecological disruption and outbreaks of highly destructive secondary pests. Rainfed cotton production uncertainty is further exacerbated by the variable monsoon rains. While hybrid cotton produces fertile seed, the resulting plant phenotypes are highly variable preventing farmers from replanting saved seed, forcing them to buy seed yearly (i.e., market capture), and effectively protecting industry Intellectual Property Rights (IPRs). The lessons gained from the ongoing market failure of hybrid Bt cotton in India are of utmost importance to its proposed introduction to Africa where, similar to India, cotton is grown mainly in poor rainfed smallholder family farms, and hence similar private–corporate conflicts of interest will occur. Holistic field agroecological studies and weather-driven mechanistic analyses are suggested to help foresee ecological and economic challenges in cotton production in Africa.High-density short-season (HD-SS) non-hybrid non-genetically modified irrigated and rainfed cottons are viable alternatives for India that can potentially produce double the yields of the current low-density hybrid system.
Broodstock nutritional programming differentially affects the hepatic transcriptome and genome-wide DNA methylome of farmed gilthead sea bream (Sparus aurata) depending on genetic background
Authors: Naya-Català F. , Belenguer A. , Montero D. , Torrecillas S. , Soriano B. , Calduch-Giner J. , Llorens C. , Fontanillas R. , Sarih S. , Zamorano M. J. , Izquierdo M. , Pérez-Sánchez J. 
Published: November 2023

Abstract
Background
Broodstock nutritional programming improves the offspring utilization of plant-based diets in gilthead sea bream through changes in hepatic metabolism. Attention was initially focused on fatty acid desaturases, but it can involve a wide range of processes that remain largely unexplored. How all this can be driven by a different genetic background is hardly underlined, and the present study aimed to assess how broodstock nutrition affects differentially the transcriptome and genome-wide DNA methylome of reference and genetically selected fish within the PROGENSA® selection program.

Results
After the stimulus phase with a low fish oil diet, two offspring subsets of each genetic background received a control or a FUTURE-based diet. This highlighted a different hepatic transcriptome (RNA-seq) and genome-wide DNA methylation (MBD-seq) pattern depending on the genetic background. The number of differentially expressed transcripts following the challenge phase varied from 323 in reference fish to 2,009 in genetically selected fish. The number of discriminant transcripts, and associated enriched functions, were also markedly higher in selected fish. Moreover, correlation analysis depicted a hyper-methylated and down-regulated gene expression state in selected fish with the FUTURE diet, whereas the opposite pattern appeared in reference fish. After filtering for highly represented functions in selected fish, 115 epigenetic markers were retrieved in this group. Among them, lipid metabolism genes (23) were the most reactive following ordering by fold-change in expression, rendering a final list of 10 top markers with a key role on hepatic lipogenesis and fatty acid metabolism (cd36, pitpna, cidea, fasn, g6pd, lipt1, scd1a, acsbg2, acsl14, acsbg2).

Conclusions
Gene expression profiles and methylation signatures were dependent on genetic background in our experimental model. Such assumption affected the magnitude, but also the type and direction of change. Thus, the resulting epigenetic clock of reference fish might depict an older phenotype with a lower methylation for the epigenetically responsive genes with a negative methylation-expression pattern. Therefore, epigenetic markers will be specific of each genetic lineage, serving the broodstock programming in our selected fish to prevent and mitigate later in life the risk of hepatic steatosis through changes in hepatic lipogenesis and fatty acid metabolism.
Isolation of a novel multiple-heavy metal resistant Lampropedia aestuarii GYF-1 and investigation of its bioremediation potential
Authors: Yu Lan , Zhang Tao , Yang Jiacheng , Zhang Rongfei , Zhou Junbo , Ding Fan , Shao Chaogang , Guo Rongkai 
Published: November 2023

Abstract
Background
Heavy metal contamination has been a severe worldwide environmental issue. For industrial pollutions, heavy metals rarely exist as singular entities. Hence, researches have increasingly focused on the detrimental effect of mixed heavy metal pollution. Genome analysis of Lampropedia strains predicted a repertoire of heavy metal resistance genes. However, we are still lack of experimental evidence regarding to heavy metal resistance of Lampropedia, and their potential in mixed heavy metal removal remain elusive.

Results
In this study, a Lampropedia aestuarii strain GYF-1 was isolated from soil samples near steel factory. Heavy metal tolerance assay indicated L. aestuarii GYF-1 possessed minimal inhibition values of 2 mM, 10 mM, 6 mM, 4 mM, 6 mM, 0.8 mM, and 4 mM for CdCl2, K2CrO4, CuCl2, NiCl2, Pb(CH3COO)2, ZnSO4, and FeCl2, respectively. The biosorption assay demonstrated its potential in soil remediation from mixed heavy metal pollution. Next the draft genome of L. aestuarii GYF-1 was obtained and annotated, which revealed strain GYF-1 are abundant in heavy metal resistance genes. Further evaluations on differential gene expressions suggested adaptive mechanisms including increased lipopolysaccharides level and enhanced biofilm formation.

Conclusion
In this study, we demonstrated a newly isolated L. aestuarii GYF-1 exhibited mixed heavy metal resistance, which proven its capability of being a potential candidate strain for industrial biosorption application. Further genome analysis and differential gene expression assay suggest enhanced LPS and biofilm formation contributed to the adaptation of mixed heavy metals.