bluuebunny/crossref_metadata_2025_split huggingface dataset:
ESG‐Firm Performance Nexus: Evidence From an Emerging Economy
Authors: Biju Ajithakumari Vijayappan Nair , Geetha Sreelekshmi , Prasad Salu , Sasidharan Aghila , Jayachandran Ambili 
Published: January 2025

ABSTRACTFirms worldwide are strengthening environmental, social and governance (ESG) factors, indicating a bidirectional association between financial and non‐financial performance. Understanding the ambiguity around the predictors of the firm's ESG performance, we attempt to reappraise the ESG‐ firm performance (FP) linkage using the firms indexed in the NIFTY 100 ESG index spanning 2014 to 2023. Our findings highlight that market forces significantly influence firms' ESG performance; however, in emerging economies, the direct relationship between ESG and FP appears to be insignificant. Surprisingly, corporate governance positively moderates the ESG–FP linkage, strengthening this association. Among the four proxies for market forces, the Volatility Index (VIX) shows a significant impact, where higher market volatility is associated with improved ESG performance, and lower volatility corresponds to weaker ESG performance. Conversely, the World Uncertainty Index (WUI) exhibits a negative significance, suggesting that higher WUI adversely affects the ESG performance of firms in emerging economies, while lower WUI has a favourable effect. Green bonds have a positive and significant effect on overall ESG performance and on social and governance dimensions; however, their influence on environmental performance is not significant, raising concerns about potential greenwashing trends. Strikingly, our findings indicate that emerging economy firms do not consider systematic risk, suggesting that investors' risk perceptions remain unchanged regardless of whether firms over‐ or under‐invest in ESG initiatives. Our research calls for greater attention to policymakers by providing accurate reasonings for the ESG performance of emerging economy firms.
Exploring the Impact of Supply Chain Digital Transformation on Supply Chain Performance: An Empirical Investigation
Authors: Rana Jeetu , Daultani Yash , Goswami Mohit , Kumar Sushil 
Published: January 2025

ABSTRACTIn an era characterized by rapid technological advancements and global supply chain complexities, Supply Chain Digital Transformation (SCDT) has emerged as a critical enabler of superior Supply Chain Performance (SCP). Grounded in Systems Theory and Digital Empowerment Theory, this study explores the mechanisms through which SCDT enhances SCP, emphasizing the mediating roles of Supply Chain Integration (SCI), Agility (SCA), and Resilience (SCRes). Employing a mixed‐methods approach, the research integrates insights from semi‐structured interviews with a survey‐based methodology, validated through Partial Least Squares Structural Equation Modeling (PLS‐SEM). The findings reveal that SCDT significantly enhances SCP, both directly and indirectly, by fostering integration, agility, and resilience within supply chains. The study also points to many novel findings, for instance, advanced digital adopters and larger firms experience more pronounced impacts of SCDT on SCP than recent adopters and smaller counterparts. This research offers theoretical contributions by integrating dual theoretical perspectives to provide a holistic understanding of SCDT's impact on SCP and practical implications for organizations operating in dynamic and uncertain environments. By situating its findings within the context of Indian manufacturing, the study extends the discourse on digital transformation to emerging economies, highlighting the transformative potential of digital technologies in building resilient and agile supply chains.
Horizontal platelet‐rich fibrin versus advanced platelet‐rich fibrin plus in gingival recession management
Authors: Sridhar Kavitha , Tadepalli Anupama , Parthasarathy Harinath , Cholan Priyanka K. , Ramachandran Lakshmi 
Published: January 2025

AbstractBackgroundNewer generation platelet concentrates, such as advanced platelet‐rich fibrin plus (A‐PRF+) obtained following low‐speed centrifugation concept and horizontal platelet‐rich fibrin (H‐PRF) obtained from swing out and bucket system, showed increased platelet entrapment and growth factor release in the in‐vitro studies. This prospective study aimed to evaluate and compare the clinical outcomes of A‐PRF+ and H‐PRF membranes in the treatment of gingival recession defects. The objectives of this study were to compare the changes in the recession height (RH) and the mean root coverage percentage (MRC%) between and within the research groups.MethodsForty‐four systemically healthy patients diagnosed with 84 Cairo's RT 1 and RT 2 gingival recession defects in the maxillary anterior and premolars were randomly treated with a combination of the coronally advanced flap (CAF) and A‐PRF+ membrane (n = 22 subjects) or H‐PRF membrane (n = 22 subjects). Patients were reviewed at 3 and 6 months postoperatively. Parameters including RH, MRC%, complete root coverage (CRC), gingival thickness, keratinized tissue height, and root coverage esthetic scores were documented.ResultsBoth treatments resulted in a significant reduction in RH (p < 0.001). The CAF + A‐PRF+ group demonstrated a reduction in RH from 2.47 ± 1.00 mm to 0.59 ± 0.52 mm and the MRC% was 76.33 ± 22.54%, at 6 months. In the CAF+H‐PRF group, the mean RH decreased from 2.43 ± 1.01 mm to 0.38 ± 0.59 mm and the MRC% was 85.51 ± 19.87%. Three‐ and six‐month intergroup analysis revealed statistically insignificant differences in the observed clinical parameters between the groups (p > 0.05).ConclusionsThe study found that both CAF + H‐PRF and CAF + A‐PRF+ protocols resulted in similar clinical outcomes while treating maxillary gingival recession defects.Plain language summaryNumerous modifications have been proposed to improve the growth factor content in the platelet concentrates and thereby therapeutic potential. This study compared platelet‐derived membranes obtained by two different spin protocols in the treatment of gum recession. Forty‐four patients were treated with either platelet‐derived membrane obtained by horizontal spin protocol (test group) or low‐speed spin concept (control group). Both treatment methods resulted in satisfactory healing. At the end of 6 months, no differences were noted with regard to the changes in clinical measurements and root coverage percentage indicating similar clinical efficacy of both preparatory techniques.
Visual Expansion and Real‐Time Calibration for Pan‐Tilt‐Zoom Cameras Assisted by Panoramic Models
Authors: Cai Liangliang , Zhou Zhong 
Published: January 2025

ABSTRACTPan‐tilt‐zoom (PTZ) cameras, which dynamically adjust their field of view (FOV), are pervasive in large‐scale scenes, such as train stations, squares, and airports. In real scenarios, PTZ cameras are required to quickly judge their directions using contextual clues from the surrounding environment. To achieve this goal, some research projects camera videos into three‐dimensional (3D) models or panoramas and allows operators to establish spatial relationships. However, these works face several challenges in terms of real‐time processing, localization accuracy, and realistic reference. To address this problem, a visual expansion and real‐time calibration for PTZ cameras assisted by panoramic models is proposed. The calibration method consists of three parts: Providing a real environment background by building a panoramic model, meeting the needs of real‐time processing by establishing a PTZ camera motion estimation model and achieving high‐precision alignment between PTZ images and panoramic models using only two feature point pairs. Our methods were validated using both the public and our Scene dataset. The experimental results indicate that our method outperforms other state‐of‐the‐art methods in terms of real‐time processing, accuracy, and robustness.
Near‐Neutral pH Sensing by Azoheteroarene Dyes
Authors: Hashim P. K. , Ahmad Shifa , Madappuram Cheruthu Nusaiba , Sahu Saugata , Tamaoki Nobuyuki 
Published: January 2025

AbstractWe serendipitously discovered a novel series of azoheteroarene dyes capable of detecting pH variations in near‐neutral solutions. These dyes feature thiazole, thiadiazole, triazole, pyrazole, or benzothiazole heteroaryls linked to hydroxyphenyl azo groups. They exhibit distinctive light absorption properties in aqueous solutions and show notable color changes in a narrow pH range, visible to the naked eye. Both experimental data and quantum calculations suggest a plausible mechanism for their function as pH indicators. Additionally, these azoheteroarene dyes effectively monitor pH in complex environments, and we show their use for detecting the pH change of culture medium containing growing cancer cells.
Self‐Assembly of Antisense DNA‐Camptothecin Amphiphile into Glutathione‐Responsive Nanoparticles for Combination Cancer Therapy
Authors: Krishna Anusree , Babulal Anupama , Sajeev Mareena , Ravi Nidhin , Raj Gowtham , Antony Anitta , Dev Narendradev Nikhil , Murty Srinivasula Srinivasa , Varghese Reji 
Published: January 2025

AbstractRecent years have witnessed the rapid growth of combination therapy for the treatment of cancer. Chemo and antisense DNA therapies are two clinically proven and efficient treatment modalities for cancer. However, direct delivery of both chemo and antisense oligonucleotides into the cancerous cells is challenging and hence there is a high demand for the development of new strategies that permit the direct delivery of chemo and antisense therapeutic agents in a targeted fashion. Herein, we show a supramolecular approach for the direct delivery of hydrophobic chemo drug and cell impermeable antisense oligonucleotide into a cancer cell in a targeted fashion. Synthesis of an amphiphile (DNA1‐CPT) consist of hydrophobic camptothecin (CPT) conjugated to an antisense oligonucleotide (DNA1) via glutathione‐responsive disulphide linker is reported. Self‐assembly of DNA1‐CPT results in the formation of GSH‐responsive NPs with CPT as the hydrophobic core and DNA1 as the hydrophilic shell. Self‐assembled NPs exhibits excellent cellular internalization via endocytosis pathway, and the high concentration of glutathione inside the cancer cells causes the cleavage of disulphide bond of the NPs and trigger the simultaneous release of CPT and DNA1a. Enhanced cytotoxicity is observed for the NPs due to the synergetic combination of chemo and antisense DNA therapies.
Half‐Sandwich Organometallic Ir(III) and Ru(II) Compounds and their Interactions with Biomolecules
Authors: Kozieł Sandra , Wojtala Daria , Szmitka Magdalena , Lesiów Monika , Ziółkowska Aleksandra , Sawka Jacek , Del Carpio Edgar , Crans Debbie C. , Komarnicka Urszula K. 
Published: January 2025

AbstractThis review highlights how a Ir(III) and Ru(II) coordination complexes can change theirs cytotoxic activity by interacting with a biomolecules such as deoxyribonucleic acid (DNA), human albumins (HSA), nicotinamide adenine dinucleotide (NADH), and glutathione (GSH). We have selected biomolecules (DNA, NADH, GSH, and HSA) based on their significant biological roles and importance in cellular processes. Moreover, this review may provide useful information for the development of new half‐sandwich Ir(III) and Ru(II) complexes with desired properties and relevant biological activities. Additionally, the examples discussed here may help us better understand what happens to a metal‐based drug once it enters the body.
Exploring Supramolecular Frustrated Lewis Pairs
Authors: Hawkins Paige R. , Hawes Chris S. , Matthews Peter D. 
Published: January 2025

AbstractFrustrated Lewis pairs (FLPs) have rapidly become one of the key metal‐free catalysts for a variety of chemical transformations. Embedding these catalysts within a supramolecular assembly can offer improvements to factors such as recyclability and selectivity. In this review we discuss advances in this area, covering key supramolecular assemblies such as metal organic frameworks (MOFs), covalent organic frameworks (COFs), polymers and macrocycles.
Highly Efficient Recovery of Cobalt‐Ion Containing Waste Deep Eutectic Electrolytes: A Sustainable Solvent Extraction Approach
Authors: Wang Jie , Wang Chaowu , Zhang Qibo 
Published: January 2025

AbstractEfficient recovery of metals from secondary resources is essential to address resource shortages and environmental crises. The development of a cheap, environmentally friendly, and highly efficient recovery pathway is essential for resource retrieval. In this study, we propose a high‐efficiency extraction approach utilizing bis(2,4,4‐trimethylpentyl) phosphonic acid (Cyanex272) to recover cobalt from waste choline chloride/ethylene glycol (Ethaline) electrolyte containing Co(II) ions. By adjusting the water content of the system to modify the ligand of Co(II) ions, combined with pH adjustment, we achieved an extraction efficiency exceeding 99.9 % for Co(II) ions. Subsequently, oxalic acid (OA) was added as a stripping agent to achieve a recovery efficiency of over 99.4 % for cobalt. The extractant can be recycled more than 15 times after stripping. Impressively, more than 98.3 % of the water‐diluted Ethaline extraction raffinate was recovered through reduced pressure distillation while maintaining the structure of recovered Ethaline unchanged. This work provides an economical, efficient, and sustainable pathway for treating waste Ethaline electrolyte‐containing metal ions.
Anionic Ring‐Opening Polymerization of 2‐oxabicyclo[2.1.1]hexan‐3‐One: Manipulating Topology and Conformation for Circular Polymer Design
Authors: Weng Chaoqun , Tan Yanghaoyu , Tang Xiaoyan 
Published: January 2025

AbstractPolyesters featuring a linear topology and in‐chain 1,3‐cyclobutane rings, synthesized via ring‐opening polymerization (ROP) of 2‐oxabicyclo[2.1.1]hexan‐3‐one (4R‐BL, R=Bu, Ph) through a coordination‐insertion mechanism, display excellent thermal and hydrolytic stability, making them promising candidates for sustainable circular materials. However, achieving diverse topological and stereochemical structures remains challenging. Herein, we demonstrate precise control over linear and cyclic topologies of these polyesters and the conformation of in‐chain cyclobutane rings through anionic ROP of 4R‐BL with appropriate catalysts or initiators. Using tert‐butoxide (tBuOK) as the catalyst, low loading (0.05–0.1 mol %) produces high‐molar‐mass cyclic polyester P(4R‐BL) (up to 571 kg/mol), whereas high loading (2 mol %) promotes transesterification and isomerization, ultimately yielding cyclic oligomers. Remarkably, the tetramer (4Ph‐BL)4 undergoes conformational turnover of the puckered cyclobutane rings and can be repolymerized into polymer P(4Ph‐BL). This establishes a “monomer ⇄ polymer ⇄ tetramer” dual closed‐loop life cycle, enhancing the potential for a circular material economy.
Antileishmanial and Antitrypanosomal Trends of Synthetic Tetralone Derivatives
Authors: Alkhaldi Abdulsalam A. M. , de Koning Harry P. , Bukhari Syed Nasir Abbas 
Published: January 2025

ABSTRACTLeishmaniasis and trypanosomiasis are parasitic diseases that are closely linked to poverty, pose significant local burdens, and are common in tropical and subtropical regions. Various synthetic tetralone derivatives were studied as potential scaffolds for antileishmanial and antitrypanosomal activities. The compounds were studied for their effectiveness against multiple kinetoplastid protozoan pathogens: Leishmania major, Leishmania mexicana, and bloodstream trypomastigotes of Trypanosoma brucei brucei. Two different strains of T. b. brucei were used. The first strain was the wild‐type Trypanosoma brucei (s427‐WT), and the second strain was the multidrug resistant (MDR) strain B48, which was produced by deleting the TbAT1 gene from s427WT and subsequent adaptation to high levels of resistance to diamidines and organo‐arsenical drugs. Compounds 4c, 7c, 9b, and 11b showed activity against two strains of Trypanosoma and two different Leishmania species, establishing them as versatile leads with broad anti‐kinetoplastid activity. Compound 4c, a tetralone derivative with a bromo‐containing trimethoxybenzylidene moiety and methyl‐substituted cyclohexanone ring, was identified as the most potent inhibitor for both T. b. brucei strains, with EC50 values of 0.19 and 0.22 µM for WT and B48, respectively, showing the absence of cross‐resistance with the diamidine and arsenical trypanocide classes. In addition, compound 4c exhibited more potency than both controls, eflornithine and pentamidine, against the MDR strain. We conclude that tetralone derivates could be a valuable starting point for the discovery of new antiparasitic drugs.
Reopenable clip over‐the‐line method in endoscopic full‐thickness resection of gastric submucosal tumors: A historical control study
Authors: Shichijo Satoki , Uedo Noriya , Mori Hitoshi , Kawakami Yushi , Tani Yasuhiro , Iwagami Hiroyoshi , Kato Minoru , Yoshii Shunsuke , Kanesaka Takashi , Higashino Koji , Michida Tomoki , Ishihara Ryu , Shinno Naoki , Hara Hisashi , Yanagimoto Yoshitomo , Yamamoto Kazuyoshi , Omori Takeshi 
Published: January 2025

AbstractObjectivesEndoscopic full‐thickness resection for gastric submucosal tumors is gradually gaining popularity, and secure and amenable closure is key to its success. This study aimed to compare the reopenable clip over‐the‐line method with the purse‐string method for defect closure after endoscopic full‐thickness resection for gastric submucosal tumors.MethodsThis historical control trial included 37 consecutive patients with 37 gastric submucosal tumors, who underwent endoscopic full‐thickness resection between January 2021 and July 2024. All lesions were resected en bloc. After excluding three patients who underwent non‐full‐thickness resection, 34 patients were analyzed. Post‐endoscopic full‐thickness resection defects were closed using the purse‐string method (n = 18) until 2022 and the reopenable clip over‐the‐line method (n = 16) from 2023.ResultsThe median (interquartile range) time for defect closure was longer in the reopenable clip over‐the‐line method group of 33 (31–57) min than in the purse‐string method group of 26 (24–35) min (p = 0.013). The visual analog scale pain score at the umbilical region was lower (p = 0.048) after the reopenable clip over‐the‐line method than after the purse‐string method. In the reopenable clip over‐the‐line method group, post‐procedural abdominal pain was confined to the epigastrium, whereas it extended to the umbilical or left lateral regions in the purse‐string method group. The reopenable clip over‐the‐line method group commenced the diet (p = 0.001) and discharged (p = 0.024) earlier than the purse‐string method group.ConclusionsReopenable clip over‐the‐line method facilitated secure post‐endoscopic full‐thickness resection defect closure, reduced post‐procedural abdominal pain, and shortened the fasting and hospitalization periods after endoscopic full‐thickness resection in gastric submucosal tumors.
Soil Decomposer Can Regulate the Legacy Effect of Photodegradation on Forest Marcescent Litter Decomposition, but Emerging Microplastics Disrupt This
Authors: Tian Kai , Wang Xin , Ye Rumeng , Wang Yingqi , Chen Zhicheng , Liu Xiaojing , Wang Wenxia , Yao Lunguang 
Published: January 2025

ABSTRACTPhotodegradation—photochemical mineralization of standing litters—often exerts a legacy effect aiding biodegradation in soil (PLE), which is overlooked in deciduous forests containing marcescent leaves. Meanwhile, increasing anthropogenic microplastics have deposited in forests, how they would affect the PLE on subsequent litter bio‐decomposition is currently unknown. Here, we employed an ultraviolet‐accelerated aging chamber to replicate the abiotic photodegradation process of a naturally marcescent tree, Lindera glauca, then manipulated mesocosm bio‐incubations to quantify how decomposers (microbial alone or with soil animals) and microplastic contamination would interactively affect the PLE. We found abiotic photodegradation significantly decreased litter lignin content before and after the bio‐incubation. During an early phase decomposition, lignin lost greatly and displayed a crucial role in determining the ways that soil animal and photodegradation affect the bio‐decomposition. Microbial decomposer alone led to a positive PLE universally. Soil animals depressed microbial biomass and inhibited the microbial‐mediated PLE in unpolluted mesocosms but intensified the PLE in contaminated soils. We conclude that decomposer interactions can attenuate PLE, but microplastics will disrupt the established equilibrium, making contaminated soil more susceptible to photodegradation‐induced litter chemical changes. This promotes integration of radiation and emerging pollution to further our understanding of biogeochemical cycle in forest ecology.
Frontopolar Cortex Interacts With Dorsolateral Prefrontal Cortex to Causally Guide Metacognition
Authors: Kapetaniou Georgia E. , Moisa Marius , Ruff Christian C. , Tobler Philippe N. , Soutschek Alexander 
Published: January 2025

ABSTRACTAccurate metacognitive judgments about an individual's performance in a mental task require the brain to have access to representations of the quality and difficulty of first‐order cognitive processes. However, little is known about how accurate metacognitive judgments are implemented in the brain. Here, we combine brain stimulation with functional neuroimaging to determine the neural and psychological mechanisms underlying the frontopolar cortex's (FPC) role in metacognition. Specifically, we evaluate two‐layer neural architectures positing that FPC enables metacognitive judgments by communicating with brain regions encoding first‐order decision difficulty. In support of two‐layer architectures of metacognition, we found that high‐intensity transcranial alternating current stimulation (tACS; 4 mA peak‐to‐peak) over FPC impaired metacognitive accuracy; at the neural level, this impairment was reflected by reduced coupling between FPC and dorsolateral prefrontal cortex (DLPFC), particularly during difficult metacognitive judgments. We also evaluated conceptual accounts assuming that metacognition relies on self‐directed mentalizing. However, we observed no influence of FPC tACS on mentalizing performance and only a weak overlap of the networks underlying metacognition and mentalizing. Together, our findings put the FPC at the center of a two‐layer architecture that enables accurate evaluations of cognitive processes, mainly via the FPC's connectivity with regions encoding first‐level task difficulty, with little contributions from mentalizing‐related processes.