bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Deep Learning–Based Approach to Estimate Paneth Cell Granule Area in Celiac Disease
Authors: Alharbi Ebtihal , Rajaram Ajay , Côté Kevin , Farag Mina , Maleki Farhad , Gao Zu-Hua , Maedler-Kron Chelsea , Marcus Victoria , Fiset Pierre Olivier 
Published: October 2023

Context.—
Changes in Paneth cell numbers can be associated with chronic inflammatory diseases of the gastrointestinal tract. So far, no consensus has been achieved on the number of Paneth cells and their relevance to celiac disease (CD).

Objectives.—
To compare crypt and Paneth cell granule areas between patients with CD and those without CD (non-CD) using an artificial intelligence–based solution.

Design.—
Hematoxylin–eosin–stained sections of duodenal biopsies from 349 patients at the McGill University Health Centre were analyzed. Of these, 185 had a history of CD and 164 were controls. Slides were digitized, and NoCodeSeg, a code-free workflow using open-source software (QuPath, DeepMIB), was implemented to train deep learning models to segment crypts and Paneth cell granules. The total area of the entire analyzed tissue, epithelium, crypts, and Paneth cell granules was documented for all slides, and comparisons were performed.

Results.—
A mean intersection-over-union score of 88.76% and 91.30% was achieved for crypt areas and Paneth cell granule segmentations, respectively. On normalization to total tissue area, the crypt to total tissue area in CD was increased and the Paneth cell granule area to total tissue area decreased when compared to non-CD controls.

Conclusions.—
Crypt hyperplasia was confirmed in CD compared to non-CD controls. The area of Paneth cell granules, an indirect measure of Paneth cell function, decreased with increasing severity of CD. More importantly, our study analyzed complete hematoxylin-eosin slide sections using an efficient and easy to use coding-free artificial intelligence workflow.
Zkušenosti s realizací dětského příměstského sportovního tábora v době pandemie COVID - 19
Authors: Větrovská Renata , Větrovský Jan 
Published: October 2023

Příspěvek popisuje zkušenosti trenérů a instruktorů ze sportovních příměstských táborů během pandemie COVID - 19. Ze sledování dětí účastnících se táborů po roce zavřených sportovišť a domácí izolace jsme zaznamenali nárůst inaktivity a celkové pohodlnosti. S tím souvisí i větší výskyt dětské nadváhy a obezity, vadného držení těla a jiných fyzických i psychických poruch. Oproti táborům v minulých letech přibylo dětí, které bylo obtížnější motivovat k pohybu a kterým chyběl tolik na táboře potřebný „kolektivní duch“. Příspěvek je současně varováním a výzvou k akci pro všechny profesionály zabývající se problematikou zdravého vývoje dětí a dospívajících.
Stability of anisotropic parabolic equations without boundary conditions
Authors: Zhan Huashui , Feng Zhaosheng 
Published: October 2023

In this article, we consider the equation $$ u_t= \sum_{i=1}^N \big(a_i(x)|u_{x_i}|^{p_i(x)-2}u_{x_i}\big)_{x_i}, $$ with \(a_i(x), p_i(x)\in C^1(\overline{\Omega})\) and \(p_i(x)>1\). Where \(a_i(x)=0\) if \(x\in\partial \Omega\), and \(a_i(x)>0\) if \(x\in \Omega\), without any boundary conditions. We propose an analytical method for studying the stability of weak solutions. We also study the uniqueness of a weak solution, and establish its stability under certain conditions.
For more information see https://ejde.math.txstate.edu/Volumes/2020/74/abstr.html
Existence and concentration of positive ground states for Schrodinger-Poisson equations with competing potential functions
Authors: Wang Wenbo , Li Quanqing 
Published: October 2023

This article concerns the Schrodinger-Poisson equation $$\displaylines{ -\varepsilon^2\Delta u+V(x)u+K(x)\phi u=P(x)|u|^{p-1}u+Q(x) |u|^{q-1}u,\quad x\in\mathbb{R}^3,\cr -\varepsilon^2\Delta \phi=K(x)u^2,\quad x\in\mathbb{R}^3, }$$ where \(3<q<p<5=2^{\ast}-1\). We prove that for all \(\varepsilon>0\), the equation has a ground state solution. The methods used here are based on the Nehari manifold and the concentration-compactness principle. Furthermore, for \varepsilon>0 small, these ground states concentrate at a global minimum point of the least energy function.
For more information see https://ejde.math.txstate.edu/Volumes/2020/78/abstr.html
Implementação da Telemedicina na Atenção Primária à Saúde
Authors: Pampolha Clevia da Silva , Nunes Jônatas Lima de Bem , Cunha Ernani Pereira da , Bellot Rogério Gentil , Soares Marcos Rafael Rodrigues 
Published: October 2023

Apresentamos a experiência da participação do Centro de Estudos e Pesquisas Dr. João Amorim (CEJAM) na implementação da telemedicina nas unidades de saúde do território de Capão Redondo e Jardim Ângela, região sul do Município de São Paulo -SP.
DİASPORADA BİR UYANIŞ VE VAR OLMA HAMLESİ OLARAK: ALEVİLERİN SESİ DERGİSİ
Authors: ÇEVİK Selman 
Published: October 2023

DİASPORADA BİR UYANIŞ VE VAR OLMA HAMLESİ OLARAK
ALEVİLERİN SESİ DERGİSİ
Selman Çevik
Selçuk Üniversitesi Sosyoloji Anabilim Dalı Yüksek Lisans Öğrencisi, selmancevik.06@gmail.com
0000-0002-3046-563X
Özet
1960 yılında Türkiye’den Avrupa’ya başlayan işgücü göçü ve sonrasında ortaya çıkan anlamlar bütünü bugün 60 yıllık bir geçmişi içerisinde barındırmaktadır. Türkiye’nin yurt dışındaki varlığı ve ona yönelik politikalar ile Türk toplumunun Avrupa’daki varlığı farklı dinamikler göz önüne alındığında önemli bir konumda bulunmaktadır. Türk diasporasının sivil toplum kuruluşları ve kamusal alanda varlıklarının da bu dinamikler içerisinde dikkat çekici bir noktada bulunduğu değerlendirildiğinde konunun hem Türkiye hem de Avrupa sathında önemli olduğu görülmektedir. Türk diasporasının önemli ve öne çıkan sivil toplum kuruluşları mevcuttur. Bu kuruluşlar belirli siyasi, dini, ideolojik ya da farklı gerekçelerle bir araya gelebilmektedir. Bu çalışmada Avrupa’da yaşayan Alevi Toplumu’nun oluşturduğu ve ön plana çıkan bir sivil toplum kuruluşu olan Avrupa Alevi Birlikleri Federasyonu bünyesinde 1990’lı yıllardan beri çıkarılmakta olan Alevilerin Sesi Dergisi üzerinden Alevi Toplumu’nun yaşadığı süreçlerin bu dergide nasıl yansıdığına dair bir analiz gerçekleştirilmiştir. Alevilerin Avrupa özelinde “var olma” süreçleri, bu süreç içerisinde meydana gelen ve bunları oluşturan dinamikler ele alınmaya çalışılmıştır. Konunun Türkiye’nin dinamiklerinden ayrı değerlendirilemeyeceği göz önüne alındığında Aleviliğin veya Alevi Toplumu’nun buna bağlı olarak bugün geldiği süreç ve sonrası için bir perspektif sunulmuştur.
Anahtar Kelimeler: Aleviler, Alevilik, Alevilerin Sesi Dergisi, Yurt Dışı Türkler, Diaspora
การมีส่วนร่วมทางการเมืองในประเทศไทย: การทำให้เป็นประชาธิปไตยด้วยการงบประมาณแบบมีส่วนร่วม
Authors: วังกานนท์ รัฐศิรินทร์ 
Published: October 2023

งานวิจัยเชิงคุณภาพนี้มีวัตถุประสงค์สามประการ คือ 1) เพื่อศึกษาสภาพการมีส่วนร่วมในกระบวนการงบประมาณขององค์กรปกครองส่วนท้องถิ่นในประเทศไทย 2)เพื่อวิเคราะห์บทบาทของการงบประมาณแบบมีส่วนร่วมต่อการทำให้เป็นประชาธิปไตย 3) เพื่อนำเสนอรูปแบบที่เหมาะสมของการนำงบประมาณแบบมีส่วนร่วมมาใช้ในประเทศไทย ด้วยการศึกษาจากกรณีศึกษา 3 แห่ง ผลการศึกษาพบว่า แม้ว่าองค์กรปกครองส่วนท้องถิ่นได้ส่งเสริมให้เกิดการมีส่วนร่วมในการบริหารงานแล้วก็ตาม แต่กระบวนการจัดทำงบประมาณยังไม่เป็นไปตามหลักการของการงบประมาณแบบมีส่วนร่วมตามที่ได้ดำเนินการในประเทศต้นแบบหลายประเทศ โดยเฉพาะอย่างยิ่งคือไม่ได้ใช้กระบวนการปรึกษาหารือในการตัดสินใจกำหนดงบประมาณ อย่างไรก็ตามการงบประมาณแบบมีส่วนร่วมมีโอกาสนำมาซึ่งผลลัพธ์ที่พึงปรารถนาซึ่งสอดคล้องกับหลักการทำให้เป็นประชาธิปไตย และเพื่อให้บรรลุเป้าประสงค์จำเป็นต้องอาศัยความร่วมมือจากทุกฝ่าย ปรับทัศนคติของผู้เกี่ยวข้อง ตลอดจนการพัฒนากลไกทางกฎหมายที่เหมาะสม
TINGKAT STRES MAHASISWA DALAM PEMBELAJARAN MELALUI MEDIA ZOOM DI STIK BUDI KEMULIAAN PADA MASA PANDEMI COVID-19
Authors: Handayani Lili , Hastuti Sri , Endah Fitria 
Published: October 2023

Latar belakang: Pada awal tahun 2020, COVID-19 menjadi masalah Kesehatan dunia. Kasus ini diawali dengan informasi dari (Badan Kesehatan Dunia/World Health Organization (WHO)
Penyebaran wabah yang sangat cepat sehingga setiap negara harus bertindak cepat untuk menekan angka penyebaran dan kejadian COVID-19. Semua kegiatan pembelajaran beralih ke pembelajaran daring tidak terkecuali pembelajaran di perguruan tinggi. Pembelajaran tetapi dengan berjalannya proses pembelajaran, mahasiswa mengalami beberapa kesulitan, seperti sinyal yang kurang mendukung,, banyak gangguan belajar ketika dirumah, materi yang disampaikan sulit untuk dipahami, Hal tersebut dapat menimbulkan stress yang dialami oleh mahasiswa
Metode Penelitian: Jenis penelitian yang digunakan bersifat deskriptif. Sampel dipilih secara purprosive sampling menggunakan data primer yaitu menggunakan kusioner sebagai pedoman wawancara atau google form dan disebarkan melalui WhatsApp Group.
Hasil Penelitian: Hasil penelitian dari 88 responden didapatkan distribusi pengetahuan tentang gejala stres adalah kategori Baik yaitu 86 mahasiswa (97,7%), distribusi tingkat stres berdasarkan efektifitas didapatkan bahwa kategori Tidak Efektif yaitu 72 mahasiswa (81,8%), distribusi tingkat stres berdasarkan lingkungan didapatkan hasil Kategori Setuju yaitu 42 mahasiswa ( 47,7%) dan untuk distribusi perilaku didapatkan hasil Hampir Selalu yaitu sebanyak 53 mahasiswa ( 60,2%)
Kata Kunci: Pembelajaran Via Zoom, Tingkat Stres, Pandemi Covid-19
Development of Nutririch Brown Rice Kichidi Mix for Geriatric Subjects Residing in Oldage Institutions of Bangalore District, India
Authors: Bhavana, A.  , Jamuna, K. V.  , Lakshminarayan, M. T.  
Published: October 2023

Nutrition awareness was carried on in the old age institutions, which was one of the study area of the research. Brown rice is not only better for us, but it's better for the environment than white rice too. brown rice production is relatively sustainable, there is no known significant damage to air, water, land, soil, forests, etc. The study aimed at development of nutri-rich brown rice kichidi mix for geriatric subjects living in old age institutions located in Bangalore. The mean sensory score of the brown rice kichadi mix where BKM 3 variation having 60g of brown rice and 20g of green gram dhal had the best overall acceptability (8.31) in all the parameters: appearance (8.28), colour (8.03), texture (8.12), aroma (8.12) and taste (8.18). Extremely significant difference was observed in taste and overall acceptability and significant distinction was observed in texture. Nutrients composition of the brown rice kichadi mix consisted of energy 293. kcal, carbohydrates 73.29 g, protein 12.31 g and fat of 4.07 g and met the ¼th of RDA requirement of the geriatric subjects followed by moisture 6.35 per cent, and negligible quantity of crude fibre 3.96 g and ash 1.17 g. The kichadi mix contained fair amount of minerals: calcium 7.94 mg, magnesium 5.93 mg, iron 0.87 mg and zinc of 0.65 mg. Nutritional education using charts prepared based on practice of fine daily activities and importance of nutrients and nutrition taught to the 91 geriatric subjects (31 males and 60 females respectively). The ready to cook brown rice kichadi mix contained most of the food groups and provided for taste by the subjects. Majority of the geriatric subjects participated in the intervention had extremely accepted the product based on taste and consistency.
Spotting the Culprit: A Rare Case of Hematometra in a Menstruating Female with Fraser Syndrome
Authors: Khan Sameer , Macalintal Nevine , Davitt Katlin , McEachron Jennifer , Muntean Cornelia 
Published: October 2023

Background: Fraser syndrome is a rare autosomal disorder that is associated with multiple genetic abnormalities. Discussed here is one abnormality associated with the genital tract.
Case Description: A 19-year-old female with Fraser syndrome presented to the pediatric emergency department for abdominal distention and pain for two days, noted to have hematometra on CT guided imaging. Decision was made to proceed with total abdominal hysterectomy bilateral salpingoophorectomy.
Conclusion: This case highlights the rarity of Fraser syndrome with associated hematometra secondary to both internal and external genital abnormalities post-menarche. Hematometra should be a differential diagnosis in patients with syndromes that are associated with genital abnormalities as failure to drain the retained blood and tissue products, can act as a foci for infection.
Quantifying the Influence of Enriched Urban Compost and Wastes on Soil Physico-chemical and Biological Parameters of Bettahalli Village, Bangalore North Taluk: A Quantitative Analysis
Authors: Shantha Murthy B.  , Sathish A.  , Saralakumari J.  , Umashankar N.  , Seenappa C.  
Published: October 2023

Enriched urban compost enhances soil for sustainable agriculture, improving structure, water dynamics, nutrient release, microbial life, and contributing to climate change mitigation. The present study was carried out in 2022 late winter to assess the impact of enriched urban compost and wastes on soil properties. Collected Soil samples were analyzed for physical, chemical, and biological properties pre and post-maize harvest. Enriched urban compost treatments showed a slight reduction in bulk density. Increased Moisture holding capacity, pH, electrical conductivity, organic carbon, and magnesium remained mostly unchanged.
Nitrogen, phosphorus, and potassium increased significantly with enriched compost, promoting sustained nutrient release. Available sulfur rose with compost addition. DTPA-extractable Cu, Zn, Fe, Mn, and B were significantly higher with enriched compost. Chromium, nickel, lead, and cadmium remained below critical limits. Dehydrogenase and urease activities were significantly higher with enriched compost, indicating enhanced microbial action. Acid phosphatase activity increased, likely due to elevated phosphorus levels in organics, supporting P solubilizers.
Enriched urban compost enhances soil properties, promoting agricultural sustainability through climate change mitigation, improved structure, and enhanced nutrient release. Advisably, incorporating enriched urban compost into agricultural practices optimizes soil health, fosters sustainable nutrient management, and supports microbial activities, thereby enhancing agricultural productivity.
Integrated Nutrient Management Practices and their Effect on Soil Health in Relation of Enzyme Dynamics and Biota in a Long-Term Diverse Cropping System in Vertisols of Central India
Authors: Dixit Mahima , Tripathi Awadhesh Kumar 
Published: October 2023

Organic farming is gaining popularity as it maintains food yields and soil health without harming the environment. However, there is a dearth of global data on enzymes involved in the carbon, nitrogen, phosphorus, and sulphur cycles; microbial elemental stoichiometry; and soil functional diversity. On the other hand, organic farming lacks the most sensitive biological components and enzyme activity based on soil quality indices. It all started in 2004 when four of India's largest soybean-based cropping systems participated in a trial to examine the viability of nutrient management in soybean-based cropping systems (soybean-wheat, soyabean-mustard, soybean-chickpea, and soybean-linseed). Herein, we report the findings of a soybean-wheat cropping system studied for Vertisol under six nutrient management practises. Chemical characteristics of the soil were studied before and after seeding. Enzyme activity, soil microbial biomass carbon (SMBC), and microbial count were studied in biological parameters. The chemical, biological and agronomic parameters of the soybean crop were statistically examined using the Randomized Block Design. The analysis of the various parameters from the surface soils (0–15 cm). The biological activity varied significantly between treatments. The agronomical indicators also exhibited significant values in the organically treated plot. Organic treatments improved agronomic conditions, stabilised soil, and improved its nutrient content, quality, and biological activity over time. The inorganically treated plot and the state recommended dose plot had the lowest nutritional content, as suggested by the lowest biological activity parameters. Soil fertility and nutrient availability were studied in this experiment in order to comprehend why switching from chemical to integrated nutrient application practises will be helpful towards the inception of a sustainable future.
Video Turing Test: A first step towards human‐level AI
Authors: Lee Minsu , Heo Yu‐Jung , Choi Seongho , Choi Woo Suk , Zhang Byoung‐Tak 
Published: October 2023

AbstractThe development of artificial intelligence (AI) agents capable of human‐level understanding of video content and conducting conversations with humans on this basis is a promising application that people expect. However, this is a challenging task that requires the holistic integration of multimodal information with temporal dependencies and reasoning, as well as social and physical commonsense. In addition, the development of appropriate systematic evaluation methods is essential. In this context, we introduce the Video Turing Test (VTT), a blind test used to evaluate human‐likeness in terms of video comprehension ability. Moreover, we propose Vincent as a video understanding AI. We explain the configuration of VTT, the architecture of Vincent to prepare for VTT and the proposed evaluation methods for video comprehension. We also estimate the current intelligence level of AI based on our results and discuss future research directions.
Fully Recyclable Cured Polymers for Sustainable 3D Printing
Authors: Jarach Natanel , Dodiuk Hanna , Kenig Samuel , Magdassi Shlomo 
Published: October 2023

AbstractThe most prevalent materials used in the Additive Manufacturing era are polymers and plastics. Unfortunately, these materials are recognized for their negative environmental impact as they are primarily nonrecyclable, resulting in environmental pollution. In recent years, a new sustainable alternative to these materials has been emerging: Reversible Covalent Bond‐Containing Polymers (RCBPs). These materials can be recycled, reprocessed, and reused multiple times without losing their properties. Nonetheless, they have two significant drawbacks when used in 3D printing. First, some require adding new materials every reprinting cycle, and second, others require high temperatures for (re)printing, limiting recyclability, and increasing energy consumption. This study, thus, introduces fully recyclable RCBPs as a sustainable approach for radiation‐based printing technologies. This approach enables multiple (re)printing cycles at low temperatures (50 °C lower than the lowest reported) without adding new materials. It involves purposefully synthesized polymers that undergo reversible photopolymerization, composed of a tin‐based catalyst. An everyday microwave oven quickly depolymerized these polymers, obtaining complete reversibility.
“Three‐in‐One” Nanozyme Composite for Augmented Cascade Catalytic Tumor Therapy
Authors: Cheng Yue , Xia Yue‐Dang , Sun Yi‐Qing , Wang Yong , Yin Xue‐Bo 
Published: October 2023

AbstractCascade catalytic reaction exhibits simple procedure and high efficiency, such as that from the orderly assembly of different enzymes in biological systems. Mimicking of the natural cascade procedure becomes critical, but the orderly assembly of different enzymes is still challenging. Herein, single Au–Pt nanozyme is reported with “three‐in‐one” functions to initiate cascade conversions for O2 supply as mimic catalase, H2O2 production with its glucose oxidase‐like property, and •OH generation as mimic peroxidase for chemodynamic therapy (CDT). Thus, the complex assembly and cross‐talk among the different enzymes are avoided. To this end, metastable Cu2O NPs, as scaffolds, are used to anchor ultrasmall Au–Pt nanozyme, while metal–organic framework (MOF) is used to encapsulate the nanozyme for tumor microenvironment response and shielding protein adsorption. Pluronic F127 is then modified on the surface to improve hydrophilicity and biocompatibility of the composite. The endogenous acidity and glutathione in tumor degrade MOF to expose nanozyme for cascade catalytic CDT. The high photothermal conversion ability also enhances the CDT, while Cu2+ ions consume GSH to further improve CDT efficiency as augmented cascade catalytic tumor therapy. Thus, a new paradigm is provided with drug‐free single nanozyme for improving tumor therapeutic efficacy and minimizing side effects.
An All‐Silicon Metalens Integrated with a Mid‐Wave Infrared Black Phosphorus Photodiode
Authors: Lien Max R. , Wang Nan , Wenger Tobias , Wang Han , Gunapala Sarath D. , Povinelli Michelle L. 
Published: October 2023

AbstractBlack phosphorus (BP) is a promising material for mid‐wave infrared (MWIR) photodetection because of its direct tunable bandgap and compatibility with a wide range of substrates, particularly silicon. However, optical signal collection in BP devices can be limited by its absorber thickness or active area. Dielectric metasurface lenses, which can be directly integrated into a device's substrate, are a scalable approach to increase the signal collected by BP photodetectors. This work presents the design, fabrication, and characterization of an all‐silicon metasurface lens for focusing MWIR light through its substrate. Then, a BP‐MoS2heterojunction photodetector is integrated with the metalens, and MWIR photodetection increases at room temperature. These results demonstrate that integrated metasurface lenses are an excellent approach for boosting the performance of MWIR BP photodetectors.
Rh(III)‐Catalyzed Cascade Cyclization of 2‐Aryl‐3H‐indoles and CF3‐Imidoyl Sulfoxonium Ylides Toward Trifluoroacetimidoyl‐Substituted 11H‐Isoindolo[2,1‐a]indoles
Authors: Yang Zuguang , Li Pinyi , Chen Zhengkai , Wu Xiao‐Feng 
Published: October 2023

AbstractA rhodium(III)‐catalyzed C−H activation/[4+1] annulation of 2‐aryl‐3H‐indoles and CF3‐substituted imidoyl sulfoxonium ylides (TFISYs) has been achieved, producing a wide variety of trifluoroacetimidoyl‐substituted 11H‐isoindolo[2,1‐a]indoles in 51–86% yields. The cascade reaction involves C−H imidoylmethylation, tautomerization and AgOAc‐mediated C−N bond formation sequence. The reaction could be scaled up to 2 mmol scale.
Hydrogel‐Sheathed hiPSC‐Derived Heart Microtissue Enables Anchor‐Free Contractile Force Measurement
Authors: Kurashina Yuta , Fukada Keisuke , Itai Shun , Akizuki Shuichi , Sato Ryo , Masuda Akari , Tani Hidenori , Fujita Jun , Fukuda Keiichi , Tohyama Shugo , Onoe Hiroaki 
Published: October 2023

AbstractIn vitro reconstruction of highly mature engineered heart tissues (EHTs) is attempted for the selection of cardiotoxic drugs suitable for individual patients before administration. Mechanical contractile force generated in the EHTs is known to be a critical indicator for evaluating the EHT response. However, measuring contractile force requires anchoring the EHT in a tailored force‐sensing cell culture chamber, causing technical difficulties in the stable evaluation of contractile force in long‐term culture. This paper proposes a hydrogel‐sheathed human induced pluripotent stem cell (hiPSC)‐derived heart microtissue (H3M) that can provide an anchor‐free contractile force measurement platform in commonly used multi‐well plates. The contractile force associated with tissue formation and drug response is calculated by motion tracking and finite element analysis on the bending angle of the hydrogel sheath. From the experiment of the drug response, H3M is an excellent drug screening platform with high sensitivity and early testing capability compared to conventionally anchored EHT. This unique platform would be useful and versatile for regenerative therapy and drug discovery research in EHT.