bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effectiveness of hyaluronic acid in reducing adverse effects associated with inhaled hypertonic saline therapy in patients with cystic fibrosis: A systematic review and meta-analysis
Authors: Arshid Sana , Ullah Saad Ehsan , Imran Junaid , Syed Meeran Asher , Choradia Aakash , Gousy Nicole , Boparai Sukhman , Shoaib Mudassir , Shah Bidhan Bikram , Netha Aadarsh 
Published: October 2023

Background Inhaled hypertonic saline (HS) is an effective mucolytic agent in patients with cystic fibrosis (CF). However, adverse events can impair the clinical utility of hypertonic saline (HS) in this patient population. In this study, we aimed to investigate the effectiveness of hyaluronic acid (HA) in reducing these adverse events. Methods A literature search was conducted across three electronic databases (Medline, Cochrane Central, and EMBASE) from inception through February 2023. Randomized controlled trials (RCTs) assessing the impact of hyaluronic acid (HA) in reducing adverse events in patients taking hypertonic saline (HS) for CF were included in the analysis. Outcomes of interest included cough, throat irritation, unpleasant taste, and FEV1. Evaluations were reported as risk ratios (RRs) and mean differences (MDs) with 95% confidence intervals (CI). The Cochrane Risk of Bias Tool (CRBT) was employed to assess the quality of RCTs. The New Castle Ottawa Scale was used to assess the quality of observational studies. Results From the 1960 articles retrieved from the initial search, five relevant studies (n=236 patients) were included in the final analysis. Compared with patients only on HS, patients with HS and HA were significantly less likely to experience cough (RR: 0.45; 95% CI, 0.28–0.72, p=0.001), throat irritation (RR: 0.43; 95% CI, 0.22–0.81, p= 0.009), and unpleasant smell (RR: 0.43; 95% CI, 0.23 – 0.80, p=0.09). In addition, patients with HS with HA had significantly less forced expiratory volume (FEV1) (MD: -2.97; 95% CI, -3.79—2.15, p=0.52) compared to patients only on HS. Discussion The addition of HA to HS was linked to a better tolerability profile. When HS was coupled with HA, there was a reduction in all side effects. This may permit tolerance of the medication in otherwise difficult patients, improve adherence to patients receiving frequent inhalations, and improve therapeutic outcomes. Conclusion The addition of HA is advantageous in CF patients who require continuous HS therapy and have previously shown poor tolerance to therapy.
PELAKSANAAN TEKNIS PETERNAKAN DAN SITE PLANE UPTD PEMBIBITAN TERNAK UNGGUL DAN HIJAUAN PAKAN TERNAK DINAS PERKEBUNAN DAN PETERNAKAN KABUPATEN PELALAWAN
Authors: Siregar Hendri 
Published: October 2023

Livestock development is an integral part of agricultural and national development. Livestock development as an agricultural sub-sector has an important role in human life. This is related to the readiness of the livestock sub-sector in terms of providing animal food for the community. The aim of developing the livestock sub-sector is to increase income, expand employment opportunities, increase population and production as well as improve people's nutrition. In order to fulfill the community's nutrition sourced from animal protein, the priority for livestock development policies is directed to livestock business commodities that are supported by the potential of the region, so that its development will be supported by the availability of existing potential.
The research was carried out in 2022 at the UPTD of Superior Livestock Breeding (PTU) and Forage Animal Feed (HPT) of the Plantation and Livestock Service Office of Pelalawan Regency. Based on the results of the technical/research reports that have been carried out, it can be concluded as follows:
The condition of the technical implementation of animal husbandry in the existing (existing) UPTD of Superior Cattle Breeding and Forage Cattle Fodder of the Livestock Service Office of Pelalawan Regency: Viewed from the technical aspect of seed management. Livestock that has been developed has the potential to produce quality calves, Feeding using palm oil waste (cake and solid) and tofu dregs can reduce production costs, Rearing with semi-intensive and extensive term patterns can improve livestock health and reduce production costs, Services Reproductive techniques through Artificial Insemination (AI) will produce quality calves. Health services by implementing Biosecurity aspects will reduce livestock morbidity and mortality.
Analisis Elastisitas Permintaan Minyak Goreng Di kabupaten Rokan Hulu
Authors: Rini  , Laily Fitriana  , Sischa Febriani Yamesa Away  
Published: October 2023

The food needs of each region can be influenced by various factors, one of the products that has high demand is cooking oil, in the last five years, cooking oil is one of the staple foods needed by the people in Rokan Hulu district. The amount of demand for cooking oil can be measured based on the elasticity of demand for the product. This study aims to determine the factors that affect the elasticity of cooking oil demand in Rokan Hulu district and measure the value of cooking oil demand elasticity in Rokan Hulu. The research method uses the quantitative method with multiple linear regression analysis and elasticity analysis, the data used is secondary data.The results of this study show that 1) The factors that affect the demand for cooking oil in Rokan Hulu district are partially variable bulk oil prices, per capita income and population, while the variables of packaged oil prices and egg prices have no influence on cooking oil demand in Rokan Hulu district. Simultaneously, all variables have an influence on the demand for cooking oil in Rokan Hulu district. The value of determination shows that 99.6% of oil demand is influenced by all independent variables2) The elasticity of demand for cooking oil in Rokan Hulu district consists of price elasticity, namely the price of bulk cooking oil and packaged cooking oil is inelastic, income elasticity, namely per capita income is inelastic, cross elasticity, namely the population is inferior elastic and the price of chicken eggs is inelastic.
Keywords: Cooking Oil Price, Population, Income, Chicken Egg Price, Demand Elasticity
The photogrammetric approach in conical picks wear rate evaluation
Authors: Krauze Krzysztof , Mucha Kamil , Wydro Tomasz , Pawlik Jan , Wróblewska-Pawlik Aleksandra 
Published: October 2023

Abstract
The cutting tools in mining industry are especially prone to rapid wear, since most of the rocks exhibit aggressive abrasion attributes. A typical representative of fast wearing mining end-tools is a conical pick (also known as tangential-rotary cutter). In order to decrease the premature deterioration, the manufacturers and users tend to enhance the lifespan of the tool by wide range of approaches, namely heat treatment, chemical treatment, burnishing, hardfacing etc. In order to estimate the wear rate of a given pick one has to select appropriate procedure and method of evaluation. By this time, most commonly applied method is to estimate the wear rate basing on mass loss measurements of the tools being exploited with constant cutting parameters and fixed conditions. The Authors proposed also a new method of volumetric wear assessment, basing of three-dimensional photogrammetric scanning and compared the results with the outcome of traditional mass wear evaluation of the same sets of tools. Additionally, this paper contains recommendations regarding both approaches (volumetric and mass), especially focusing on the possibilities of the new method concerning measurements of the manufactured tool.
Analysis of the impact of the 5S tool and Standardization on the duration of the production process - case study
Authors: Pawlak Szymon , Nowacki Krzysztof , Kania Harald 
Published: October 2023

Abstract
The high level of competition in the manufacturing industry requires the creation of working conditions that allow for the efficient implementation of production processes. One of the solutions enabling the adaptation of production stations to improve the work performed by employees is the implementation of a management system based on the Lean Manufacturing (LM) philosophy. The purpose of this article was to determine the potential impact of the implemented LM tools, in the form of 5S and standardization, on the efficiency of the production process in specific production conditions. The methodology of the conducted research included: obtaining data before and after the implementation of LM tools (in total 12 months). The data was used to determine the effectiveness of individual operations, and then to conduct a comparative analysis using statistical tests. It was found, among others, that the implementation of LM tools resulted in an increase in the efficiency of the manufacturing process by about 11 percentage points. The obtained results confirm the thesis that a manufacturing company, in order to maintain its position on a competitive market, can improve the efficiency of processes by using tools such as LM. The selection of tools must be adequate to the implemented processes, so that they bring measurable increase in efficiency.
Hubungan pengetahuan ibu tentang MPASI dan Jenis kelamin balita dengan kejadian Stunting
Authors: Iin Setiawati  
Published: October 2023

Background: Based on the Indonesian Toddler Nutrition Status Survey (SSGBI), the number of stunting is 38%, this figure is second highest number in East Java. This survey was conducted at 33 special locations (locuses) in Bangkalan, involving 300 samples and the results were 38% experienced stunting.
Objective: This study aims to analyze the relationship between mother's knowledge about complementary foods and the sex of toddlers with the incidence of stunting.
Methods: analytic research method with a cross-sectional approach, independent variable is mother's knowledge of complementary foods and the sex of toddlers, dependent variable is stunting. The research sample was 30 toddlers. Univariate test using frequency distribution table and bivariate test with regression 0.05
Results: Most of the knowledge of mothers about complementary foods is 66.7%, statistical test shows 0.141 > 0.05 (ρ>α) meaning that there is no relationship between mother's knowledge about complementary foods and the incidence of stunting. Most of the sexes of toddlers are male, namely 60%, statistical test shows 0.014<0.05 (ρ<α) meaning that there is a relationship between the sex of toddlers and the incidence of stunting.
Conclusion: Mother's knowledge about complementary foods has no relationship with stunting, the gender of toddlers has a relationship with stunting.
FACTORS INFLUENCING THE PROCESS OF MANAGING ECONOMIC SECURITY OF ENTERPRISES IN CONDITIONS OF MILITARY CONDITION
Authors: Yepifanova Iryna , Dzhedzhula Viacheslav , Shevchuk Yevhenii 
Published: October 2023

In the conditions of martial law, ensuring economic security is highly relevant for domestic enterprises. The issue of economic security is defined by the fact that a significant number of companies located in the Eastern part of the country are forced to relocate to areas where active combat operations are not taking place. Issues related to economic security are the subject of extensive research. At the same time, it is important to assess the factors influencing the process of managing economic security in the context of martial law.
The purpose of this work is to develop a model that will enable the evaluation of factors influencing the management of economic security in conditions of martial law. Economic security of an enterprise is a comprehensive characteristic that encompasses the level of protection of all types of the enterprise's potential from internal and external threats, ensuring its stable functioning and effective development, and requires management by the enterprise's leadership. This paper analyzes the factors influencing the process of managing economic security of enterprises in conditions of martial law.
Given that economic security significantly depends on sources of funding for the enterprise, the intellectual component, the availability of an adequate workforce, and the volume of information, these factors are taken into account in the research. The distribution of factors influencing the evaluation of the efficiency indicator of economic security management is presented. The paper proposes hierarchical relationships of factors influencing the system of economic security management of an enterprise, which, unlike existing approaches, allows for a more comprehensive consideration of the factors determining the effectiveness of economic security management and the development of a mathematical model for intelligent decision support in managing economic security.
Pelatihan Budidaya Lebah Kelulut (Heterotrigona itama) Bagi DKM Masjid Ash-Shiddiq Rumbai Pekanbaru
Authors: Eni Suhesti  , Hadinoto* Hadino , Sri Utami Lestari  
Published: October 2023

Abstract
Breeding the kelulut honey bee (Heterotrigona itama) is relatively easy, not difficult to breed and care for, and produces quite a lot of honey. Breeding kelulut can be done on land that is not large, as long as the feed source in the form of sufficient nectar, pollen and resin. The Ash-Shiddiq Mosque in Umban Sari Village, Rumbai District, Pekanbaru City fulfills these requirements. The problem is that mosque DKM members do not have the knowledge and skills to do this business. The service team provides counseling, training and evaluation of activities and results. The results of partner activities have knowledge, skills in kelulut beekeeping and have obtained results in the form of honey which is one of the sources of income for the mosque. This activity has succeeded in empowering the mosque's DKM, so that it is expected to contribute to the smooth operation of the mosque.

Keywords: Beekeeping, kelulut bees (Heterotrigona itama), mosque's DKM empowerment

Abstak
Budidaya lebah madu kelulut (Heterotrigona itama) tidak asing lagi bagi sebagian masyarakat Indonesia, relatif lebih mudah dibudidayakan karena tidak menyengat dan jinak, tidak sulit perbanyakan dan perawatannya, serta dapat menghasilkan madu yang cukup banyak. Kegiatan budidaya kelulut dapat dilakukan pada lahan yang tidak terlalu luas, asalkan sumber pakan mencukupi berupa tanaman sumber nektar, pollen dan resin. Masjid Ash-Shiddiq di Kelurahan Umban Sari, Kecamatan Rumbai, Kota Pekanbaru Riau memenuhi persyaratan tersebut. Permasalahannya adalah anggota DKM masjid belum memiliki pengetahuan dan keterampilan untuk melakukan usaha budidaya lebah madu kelulut. Tim pengabdian memberikan pelatihan dan pendampingan dengan melakukan 3 tahapan kegiatan, yaitu: penyuluhan, pelatihan dan evaluasi kegiatan dan hasilnya. Hasil kegiatan pengabdian ini, mitra telah memiliki pengetahuan, keterampilan dalam budidaya lebah kelulut dan telah memperoleh hasil berupa madu yang menjadi salah satu sumber pamasukan masjid. Kegiatan ini telah berhasil memberdayakan DKM masjid, sehingga diharapkan dapat berkontribusi untuk kelancaran operasional masjid.

Kata kunci: Budidaya lebah, Lebah kelulut (Heterotrigona itama), pemberdayaan DKM Masjid.
Vladimir Ivanov’s “Jewish Manuscripts”. Part 1. The Collection And The Archive
Authors: Belkina Ekaterina 
Published: October 2023

The “Bukharian Collection” of Vladimir A. Ivanov included dozens of Jewish manuscripts. They came to the Asian Museum in St. Petersburg in 1915, and Alexander A. Freiman systematized some of them – in Judeo-Persian only – by 1918. Over the past century, there have been several (re-)inventories, so nowadays one cannot rely on those obsolete publications, working with these monuments. Part of the provenance has been lost. Basing on Ivanov’s archive and the inventory books of different years, this article is an attempt to update the information on all Jewish manuscripts acquired in Bukhara. The Aramaic and Hebrew manuscripts are new to the scientific circulation, the provenance of the Judeo-Persian manuscripts is clarified.
Ivanov’s personal notes for each manuscript are scarce. Nevertheless, they are the primary source about the manuscripts, and today his “notebook” on the “Collection” is kept in the Archive of Orientalists of the Institute of Oriental Studies RAS. Using Ivanov’s list of manuscripts and their description by Freiman, as well as the current inventory, I managed to restore the provenance of almost all monuments. Some last Hebrew manuscripts in this list are particularly difficult to identify, while other monuments within the Jewish fund have been erroneously attributed to the “Collection” for a long time. Only one manuscript from Bukhara has remained unidentified. Checking the rest of the manuscripts for Ivanov’s notes at the margins in his “notebook” helped to match and connect the archival data with the source data of the manuscripts.
TERBENTUKNYA BUDAYA POLITIK PAROKIAL DALAM TATANAN KEHIDUPAN BERNEGARA YANG DEMOKRATIS
Authors: Syuhada Otong 
Published: October 2023

Budaya politik parokial adalah budaya politik yang dapat merusak tatanan demokrasi, sebab penganut budaya politik ini tidak mau terlibat dalam proses demokrasi. Adapun tujuan dari penelitian ini adalah untuk menganalisis factor yang menjadi penyebab terbentunya budaya politik parokial. Metode yang digunakan dalam penelitian ini adalah yuridis sosiologis dengan pendekatan undang-undang dan pendekatan konseptual, Sedangkan data yang digunakan adalah data sekunder. Dari hasil penelitian ditemukan beberapa faktor yang menjadi penyebab terbentuknya budaya politik parokial seperti diantaranya adalah : Tingkat Pendidikan yang rendah, menganggap sistem politik itu tidak penting dan tidak berpengaruh kepada kehidupannya, politik dianggap sesuatu yang tabu untuk di bicarakan sebab mereka merasa bukan kapasitasnya dan merasa tidak memiliki kapabilitas, maka perlu diberikan pemahaman dan pendidikan politik agar paham pentingnya partisipasi seluruh warga masyarakat dalam berdemokrasi sehingga hak-hak individu sebagai warga negara dapat terlindungi. Oleh karena itu kedepan pemerintah harus segera membuat sebuah regulasi yang tegas untuk mengatasi beberapa faktor yang menjadi penyebab terbentuknya budaya politik parokial.
Health-Related Quality of Life in FKRP-Related Limb-Girdle Muscular Dystrophy R9
Authors: Jensen Synnøve M. , Friborg Oddgeir , Mellgren Svein Ivar , Müller Kai Ivar , Bergvik Svein , Arntzen Kjell Arne 
Published: October 2023

Background: Limb-girdle muscular dystrophy R9 (LGMDR9) is a chronic progressive hereditary muscle disease, related to the Fukutin Related Protein (FKRP) gene, that may cause major disabilities, cardiomyopathy, and ventilatory failure. Knowledge of how LGMDR9 affects health-related quality of life (HRQoL) is relevant in treatment and care. Objective: To investigate HRQoL in the Norwegian LGMDR9 population over 14 months and relation to fatigue and sleep quality. Methods: Participants (16+ years) of the Norwegian LGMDR9 cohort study completed two HRQoL measures, i.e., Individualized Neuromuscular Quality of Life questionnaire (INQoL) and the 36-item Short Form (SF-36) at baseline, 8, and 14 months and measures of fatigue and sleep quality at 9 months. Results: HRQoL response rate was 84/90 (75 c.826 C > A homozygotes and nine c.826 C > A compound heterozygotes). Compared to Norwegian normative data, all SF-36 domain scores were impaired ( p≤0.006) except mental health in males ( p = 0.05) and pain scores. During 14 months, perceived muscle weakness and the INQoL index (disease burden) worsened in c.826 C > A homozygotes. Compound heterozygotes reported more dysphagia and physical difficulties than homozygotes and showed a tendency towards worsening in weakness over time but some improvement on the INQoL index. Homozygous females reported generally poorer HRQoL and a higher burden than males. The INQoL index was related to perceived muscle weakness and fatigue, and fatigue to myalgia and mental distress. The prevalence of fatigue and poor sleep was 40% and 49%, respectively. Conclusions: The 14-month follow-up period shows a worsening of perceived weakness and burden in c.826 C > A homozygotes, which can then be expected. The prevalence and impact of fatigue indicate a need for awareness and treatment of fatigue. Myalgia and mental distress are potential targets in the treatment of fatigue, which future studies need to establish. Sleep issues and gender-specific care needs also require attention in LGMDR9.
Anticancer Potential of Ferns from Uttarakhand Region
Authors: Gupta Akhil , Sharma Rakesh , Kumar Neeraj , Bansal Mayank , Dudhe Rupesh , Gupta Shiv Kumar 
Published: October 2023

The current study deals with the anticancer potential of ferns in Uttarakhand region. The ferns are widely used by the local people of the Uttarakhand Himalaya. The present study documents anticancer and antioxidant activity of some fern plants, which are prevalent in study area along with botanical name, family, chemical constituents and their activity for medicinal use. Among all the pteridophytes examined taxa from the Pteridaceae, Polypodiaceae, and Adiantaceae exhibited significant medicinal activity. Based on our review, many pteridophytes have properties that could be used in alternative medicine for treatment of cancer.
Keywords: Anti-cancer, Anti-oxidants, Ferns, Uttarakhand.
Refractory Axillary Web Syndrome Successfully Treated with Steroid Injections: A Case Report
Authors: Munayco Maldonado Gloria , Adepoju Omotinuwe 
Published: October 2023

Background: Axillary Web Syndrome (AWS) manifests after breast cancer surgery as 1mm wide, singular, or multiple cords that can extend from the ipsilateral axilla to the antecubital fossa and further into the forearm and wrist. These cords can be painful and cause diminished range of motion. Even though there is no current standard treatment for AWS, physical therapy is recommended as the first approach in management. In refractory cases, no management has been proposed.
Case Presentation: We present a case of a 59-year-old female with right-sided breast pain and a palpable cord, refractory to one year of physical therapy, which began at the inframammary fold up towards the lumpectomy scar and further towards the axilla. Cord developed post-lumpectomy and post-radiation for a right-sided stage I invasive ductal carcinoma with negative sentinel lymph node biopsy. Based on the refractory nature of the cord, the patient underwent three treatments of steroid injections which made the cord less palpable and improved the pain. Due to persistent diminished range of motion and tenderness, the patient underwent a percutaneous needle cord disruption procedure with a last round of corticosteroid injection to prevent adherence of the cord pieces. At a 7-month follow up post-procedure, the breast cord was no longer present, and range of motion had been restored.
Conclusion: We found that percutaneous cord disruption with concurrent steroid injections can be an effective treatment for AWS refractory to physical therapy.