bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recent contributions of electronic circular dichroism to the investigation of oligopeptide conformations
Authors: Formaggio Fernando , Peggion Cristina , Crisma Marco , Kaptein Bernard , Broxterman Quirinus B. , Mazaleyrat Jean‐Paul , Wakselman Michel , Toniolo Claudio 
Published: June 2004

AbstractRecent applications in our laboratories of electronic circular dichroism to the study of peptide secondary structures and their changes under external stimuli are briefly reviewed. More specifically, this article deals with: 1) characterization of a novel peptide conformation; 2) origin of amino acid homo‐chirality on Earth; 3) bend and helical peptides as spacers; and 4) transfer and propagation of chirality in peptides. Chirality 16:388–397, 2004. © 2004 Wiley‐Liss, Inc.
Bioinversion of R‐flurbiprofen to S‐flurbiprofen at various dose levels in rat, mouse, and monkey
Authors: Leipold Douglas D. , Kantoci Darko , Murray E. David , Quiggle David D. , Wechter William J. 
Published: June 2004

AbstractInformation about the potential and extent of bioinversion of chiral drugs in laboratory animal species and humans is critical to the interpretation of preclinical pharm‐tox studies with these drugs. Unlike in the dog, guinea pig, and rabbit, in humans the 2‐arylpropionic acid (APA) R‐flurbiprofen (R‐FB) undergoes very little bioinversion to S‐flurbiprofen. The primary objective of this research was to identify laboratory animal species with an R‐ to S‐bioinversion profile similar to humans. Detailed evaluations of the pharmacokinetics parameters of R‐flurbiprofen in male and female rats and mice, and male nude rats and monkeys demonstrated R‐ to S‐bioinversion of 30% (average) in monkeys, 15–24% in mice, and ∼4% in rats. To date, no laboratory animal species has been identified with an R‐flurbiprofen bioinversion profile identical to humans. However, the rat has a bioinversion profile sufficiently similar to humans to be useful for preclinical pharm‐tox studies employing relatively short‐term dosing regimens. Chirality 16:379–387, 2004. © 2004 Wiley‐Liss, Inc.
Acute liver damage in anorexia nervosa
Authors: Di Pascoli Lorenza , Lion Alessia , Milazzo Daniela , Caregaro Lorenza 
Published: June 2004

AbstractWe report a case of a 26‐year‐old White woman with a history of anorexia nervosa who developed severe liver damage and multiorgan dysfunction. At admission to our medical unit, her body mass index (BMI) was 10.8. Biochemical evaluation showed a marked increase in serum levels of aspartate aminotransferases (AST = 9,980 IU/L), alanine aminotransferase (ALT = 3,930 IU/L), amylase (1,002 IU/L), lipase (1,437 IU/L), creatine phosphokinase (CPK; 783 IU/L), and lactate dehydrogenase (LDH = 6,830 IU/L). Glomerular filtration rate was reduced (35 ml/min), reflecting dehydration and prerenal azotemia. No other cause of acute liver damage except malnutrition was evidenced. Hydration and nutritional support were the unique medical treatment. A rapid recovery occurred in few days and all laboratory data were normal at discharge after a 37‐day hospitalization. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 114–117, 2004.
Beliefs of the public concerning the helpfulness of interventions for bulimia nervosa
Authors: Mond Jonathan M. , Hay Phillipa J. , Rodgers Bryan , Owen Cathy , Beumont Pierre J. V. 
Published: June 2004

AbstractObjectiveTo examine the beliefs of women concerning the helpfulness of various possible interventions for bulimia nervosa.MethodFace‐to‐face interviews were conducted with a community sample of 208 women aged 18–45 years. Respondents were presented with a vignette describing a fictional person meeting diagnostic criteria for bulimia nervosa and were asked to indicate whether various persons, treatments, medications, and self‐help activities would be helpful, harmful, or neither helpful nor harmful for the person described.ResultsRespondents indicated that seeing a general practitioner (GP), counselor, or dietitian was more likely to be helpful than seeing either a psychologist or a psychiatrist. GPs were perceived as the individuals likely to be most helpful for the problem described, and most likely to be approached first, whereas counseling was regarded as the most helpful treatment. Self‐help interventions, including the use of vitamins and minerals, were also highly regarded, while a minority of participants believed that anti‐depressant medication would be helpful.ConclusionsInformation concerning treatments that are effective for eating disorders should be included in prevention programs. Collaborations between mental health specialists and primary health providers are vital to ensure the optimal treatment of eating‐disordered behavior. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 62–68, 2004.
Reduction of food cravings through concurrent visuospatial processing
Authors: Kemps Eva , Tiggemann Marika , Woods Davinia , Soekov Belinda 
Published: June 2004

AbstractObjectiveTwo experiments adopted a working memory approach to evaluate the effectiveness of visuospatial tasks as a technique for reducing food cravings.MethodDieting and nondieting women were asked to form images of both food‐related and nonfood items, induced by either pictures (Experiment 1) or verbal cues (Experiment 2). They were required to concurrently perform one of three tasks that load on the visuospatial sketch pad of working memory: saccadic eye movements, dynamic visual noise, or spatial tapping.ResultsIn support of the working memory model of limited visuospatial capacity, concurrent visuospatial activity reduced the vividness of food‐related images which, in turn, reduced the intensity of the associated craving. The same pattern of results was observed across dieters and nondieters and for all stimulus types.DiscussionVisuospatial tasks may provide a useful technique for the treatment of food craving episodes in both nonclinical and clinical populations. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 31–40, 2004.
Evaluation of a school‐based program designed to improve body image satisfaction, global self‐esteem, and eating attitudes and behaviors: A replication study
Authors: McVey Gail L. , Davis Ron , Tweed Stacey , Shaw Brian F. 
Published: June 2004

AbstractObjectiveThe purpose of the current study was to evaluate the effectiveness of a life‐skills promotion program designed to improve body image satisfaction and global self‐esteem, while reducing negative eating attitudes and behaviors and feelings of perfectionism, all of which have been identified as predisposing factors to disordered eating.MethodA total of 258 girls with a mean age of 11.8 years (intervention group = 182 and control group = 76) completed questionnaires before, and 1 week after, the six‐session school‐based program, and again 6 and 12 months later.ResultsThe intervention was successful in improving body image satisfaction and global self‐esteem and in reducing dieting attitude scores at postintervention only. The gains were not maintained at the 12‐month follow‐up.DiscussionThe need to assess the influence of health promotion programs on predisposing risk factors, compared with problem‐based outcome measures, is discussed. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 1–11, 2004.
Nonresponse bias in a general population survey of eating‐disordered behavior
Authors: Mond Jonathan M. , Rodgers Bryan , Hay Phillipa J. , Owen Cathy , Beumont Pierre J. V. 
Published: June 2004

AbstractObjectiveTo investigate nonresponse bias in a two‐phase epidemiologic study of eating‐disordered behavior.MethodSelf‐report questionnaires were delivered to a community sample of women aged 18–45 drawn from the electoral roll. Follow‐up interviews were completed with a subgroup of respondents. Eating disorder psychopathology, general physical and mental health, and sociodemographic characteristics were compared among early (n = 259) and late (n = 71) respondents at the first phase of the study and among individuals with whom interviews were completed (n = 208) and individuals declining to be interviewed (n = 63) at the second phase.ResultsWith respect to levels of eating disorder psychopathology, and on all other measures, individuals who responded at the first phase of the study only after repeated reminders did not differ from those who responded to the initial mailout, and individuals who declined to be interviewed did not differ from individuals with whom interviews were completed.ConclusionsNonresponse bias among individuals declining to be interviewed is unlikely to pose a problem in two‐phase epidemiologic studies of eating disorders. Further research is needed to examine the characteristics of nonrespondents at the first phase of such studies. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 89–98, 2004.
Comparing two measures of eating restraint in bulimic women treated with cognitive‐behavioral therapy
Authors: Safer Debra L. , Agras W. Stewart , Lowe Michael R. , Bryson Susan 
Published: June 2004

AbstractObjectiveTo examine changes in dietary restraint patterns revealed by the Eating Disorders Examination Restraint subscale (EDE‐R) and the Three‐Factor Eating Questionnaire Cognitive Restraint scale (TFEQ‐CR) in a large sample of women with bulimia nervosa (BN) who completed 18 weeks of cognitive‐behavioral therapy (CBT).MethodData from 134 subjects were obtained from a larger study and analyzed using repeated‐measures analysis of variance (ANOVA).ResultsThe EDE‐R showed statistically and clinically significant decreases post‐CBT, whereas the TFEQ‐CR did not change significantly.DiscussionThis is the first study to directly compare the EDE‐R and TFEQ‐CR before and after CBT in the same population. The contrasting results suggest the two measures tap different aspects of the dietary restraint construct. The EDE‐R may primarily reflect dieting to lose weight whereas the TFEQ‐CR may reflect dieting to avoid weight gain. In assessing changes in dietary restraint targeted by CBT for BN, the TFEQ‐CR appears less useful. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 83–88, 2004.
Predictors of rehospitalization after total weight recovery in adolescents with anorexia nervosa
Authors: Castro Josefina , Gila Araceli , Puig Josefa , Rodriguez Sonia , Toro Josep 
Published: June 2004

AbstractObjectiveThe current study analyzed the variables related to rehospitalization after total weight recovery in adolescents with anorexia nervosa.MethodOne hundred and one patients first admitted for inpatient treatment, aged 11–19 years, were followed up for 12 months after discharge.ResultsTwenty‐five subjects (24.8%) required readmission after complete weight recovery and 76 (75.2%) did not. Duration of disorder, weight loss, body mass index at first admission, and global body image distortion were similar in the two groups. Patients needing readmission had a lower rate of weight gain (p < .001), a lower mean age (p = .007), a higher mean score on the Eating Attitudes Test (EAT; p = .009), and a higher percentage of hips overestimation (p = .049). In a stepwise logistic regression analysis, these three variables predicted readmission and correctly classified 77.6% of patients. Taken as discrete variables, age younger than 15 years old, EAT score above 55, and a rate of weight gain lower than 150 grams per day were associated with a higher percentage of readmissions.DiscussionThe variables most clearly related to readmission were young age, abnormal eating attitudes, and a low rate of weight gain. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 22–30, 2004.
Osteoporosis in Chinese patients with anorexia nervosa
Authors: Wong Samuel , Au Betty , Lau Edith , Lee Yvonne , Sham Aprille , Lee Sing 
Published: June 2004

AbstractObjectiveA case‐control study was conducted to determine whether bone mass is reduced in Chinese patients with anorexia nervosa (AN) and to study the risk factors for low bone mass in the same population.MethodBone mineral density (BMD) of the lumbar spine and hip was measured by dual‐energy X‐ray absorptiometry in 42 AN patients and 221 controls.ResultsPatients with AN had a significantly lower BMD in the total hip and spine compared with controls (p < .001). In AN patients, linear regression showed that lowest body mass index (BMI) was positively associated with BMD in the hip (p = .04) whereas duration of illness was negatively associated with BMD in the hip (p = .05).DiscussionChinese patients with AN are at risk of low BMD. Duration of illness and lowest BMI were significant predictors of reduced BMD in Chinese patients with AN. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 104–108, 2004.
Suicide in anorexia nervosa: A meta‐analysis
Authors: Pompili Maurizio , Mancinelli Iginia , Girardi Paolo , Ruberto Amedeo , Tatarelli Roberto 
Published: June 2004

AbstractObjectiveSuicide is a major cause of death among subjects with anorexia nervosa, but the rate of suicide among this population is very often underestimated. We conducted a meta‐analysis to compare data reported in representative studies of suicide in anorexia nervosa with data for the general population.MethodWe searched the Index Medicus until 2002 through MedLine. We also searched the World Health Statistics Annual to ascertain the suicide rate in the age group 14–25 for specific years and country.ResultsWe selected nine studies comprising 1,536 patients. Of these patients, 36 committed suicide. Results obtained for each study were processed together to calculate the mean figure for each year of suicides for 100,000 individuals suffering from anorexia nervosa.DiscussionOur meta‐analysis shows that suicide among patients with anorexia nervosa is more frequent when compared with the general population. All study analyses, except one, reported that the patients with anorexia nervosa committed suicide more often than their counterparts in the general population. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 99–103, 2004.
Anorexia nervosa and gender identity disorder in biologic males: A report of two cases
Authors: Winston Anthony P. , Acharya Sudha , Chaudhuri Shreemantee , Fellowes Lynette 
Published: June 2004

AbstractGender identity disorder is a rare disorder of uncertain etiology. The emphasis on body shape in this disorder suggests that there may be an association with anorexia nervosa.MethodWe report two cases of anorexia nervosa and gender identity disorder in biologic males who presented to an eating disorders service.ResultsOne was treated successfully as an outpatient and subsequently underwent gender reassignment surgery. The other patient required admission and prolonged psychotherapy.DiscussionDifferences between the two cases are discussed. Issues of gender identity should be considered in the assessment of male patients presenting with anorexia nervosa. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 109–113, 2004.
Accuracy in the estimation of body weight: An alternate test of the motivated‐distortion hypothesis
Authors: Vartanian Lenny R. , Herman C. Peter , Polivy Janet 
Published: June 2004

AbstractObjectiveInaccuracies in self‐reported weight are believed to represent a motivated distortion, but cognitive or perceptual biases have not been excluded. We examined the ability of participants to estimate the weight of a target person as a means of distinguishing between motivated distortions and perceptual biases.MethodParticipants (restrained eaters and unrestrained eaters; women and men) estimated the weight of a target individual, which was compared with the actual weight of the target individual.ResultsRestrained and unrestrained eaters did not differ in their estimates of the target's weight, and men underestimated the target's weight to a greater extent than did women.DiscussionThe pattern of inaccuracies observed does not parallel those found in research on self‐reported weight. This observation suggests that perceptual biases do not explain inaccuracies in self‐reported weight and that such inaccuracies may be the result of motivated distortions. Issues regarding data analysis and presentation are also discussed. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 69–75, 2004.
Predictors of the accuracy of self‐reported height and weight in adolescent female school students
Authors: Abraham Suzanne , Luscombe Georgina , Boyd Catherine , Olesen Inger 
Published: June 2004

AbstractObjectiveThe authors investigated predictors of the accuracy of self‐reported values of body weight and height in adolescent females.MethodSelf‐reported and measured weight and height values were obtained for 683 school students aged 11–18 years. Predictors of accuracy were determined for self‐reported weight, height, and body mass index (BMI; based on self‐reported values).ResultsSelf‐reported weight was underestimated. This was most likely for students with higher BMI values and actual weight. Younger, early pubertal and premenarcheal students were most likely to underestimate their height whereas older, postmenarcheal (more than 3 years) students were most likely to overestimate their height. The more exercise reported, the more accurate the height estimation. This translates to a greater underestimation of BMI as adolescents become older, have a longer duration since menarche, and exercise more.DiscussionWhen accurate information is required, clinicians should measure height and weight, particularly if the adolescent female is perimenarcheal or appears to differ from population averages for height and weight. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 76–82, 2004.
Perfectionism, body dissatisfaction, and self‐esteem in predicting bulimic symptomatology: Lack of replication
Authors: Shaw Heather E. , Stice Eric , Springer David W. 
Published: June 2004

AbstractObjectiveFew prospective studies have tested multivariate models of bulimic pathology development, but two studies have found support for a Perfectionism × Body Dissatisfaction × Self‐Esteem etiologic model (Vohs, K.D., Bardone, A.M., Joiner, T.E., Abramson, L.Y., & Heatherton, T.F., 1999;108:695–700; Vohs et al., 2001;20:476–497). The current study sought to provide an independent replication of these promising findings.MethodData from 496 adolescent girls that were followed prospectively over a 1‐year period were used to test this predictive model.ResultsAlthough our study should have provided a more sensitive test of this model because we used a sample at higher risk for bulimic symptom increases, more sensitive diagnostic interviews, a longer follow‐up period, and a larger sample, the three‐way interaction did not predict subsequent increases in bulimic symptoms.DiscussionResults suggest that the predictive power of this interactive model may not be as robust as previously believed. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 41–47, 2004.
Efficacy of sertraline for bulimia nervosa
Authors: Sloan Denise M. , Mizes J. Scott , Helbok Craig , Muck Rebekah 
Published: June 2004

AbstractObjectiveThe current study examined the efficacy of sertraline in the treatment of individuals diagnosed with bulimia nervosa.MethodEighteen women enrolled in an 8‐week open trial of sertaline. Eating disorder psychopathology and depressive symptoms were assessed at baseline and at the end of the trial using both semistructured interviews and self‐report questionnaires.ResultsFindings indicated significant reductions in eating disorder psychopathology, including the number of binges and purges per week, as well as significant reductions in depressive symptoms. In addition, participants did not experience significant weight gain or any other sertraline side effect assessed at the end of the trial compared with baseline.DiscussionFindings from the current study indicate that sertraline is efficacious in the treatment of bulimia nervosa. A double‐blind controlled trial of sertraline is recommended for future research. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 48–54, 2004.
Is major depressive disorder or dysthymia more strongly associated with bulimia nervosa?
Authors: Perez Marisol , Joiner Thomas E. , Lewinsohn Peter M. 
Published: June 2004

AbstractObjectiveResearch on adult samples has found that the comorbidity between depression and eating disorders exceeds the comorbidity of any other Axis I disorder and eating disorders. Few studies have investigated the specific associations of major depression versus dysthymia with eating disorders.MethodThis sample consisted of 937 adolescents who were repeatedly assessed until the age of 24.ResultsAnalyses revealed that dysthymia was a stronger correlate with bulimia than major depression, even while controlling for other mood disorders and a history of depression and dysthymia.ConclusionsThe presence of dysthymia in adolescence might be a possible risk factor for the development of bulimia nervosa. © 2004 by Wiley Periodicals, Inc., Int J Eat Disord 36: 55–61, 2004.
Patterns of weight change after treatment for bulimia nervosa
Authors: Carter Frances A. , McIntosh Virginia V.W. , Joyce Peter R. , Gendall Kelly A. , Frampton Christopher M.A. , Bulik Cynthia M. 
Published: June 2004

AbstractObjectiveThe current study examined changes in weight and body mass index (BMI) at 5‐year follow‐up among women treated for bulimia nervosa.MethodThe study comprised 80 women who had participated in a randomized clinical trial evaluating cognitive‐behavior therapy for bulimia nervosa. The women had attended assessments at posttreatment and at 5‐year follow‐up while not pregnant.ResultsChanges in mean weight and BMI between posttreatment and 5‐year follow‐up were small in absolute terms and were not statistically significant. However, by the 5‐year follow‐up, approximately one half of the participants had either lost (31%) or gained (18%) 5 or more kilograms or were underweight (31%) or overweight (24%) as defined by BMI. Univariate analyses suggest that it is the patients who gain weight over the follow‐up that are distinctive. Patients who gained weight over the follow‐up were more likely to have commenced menstruation at a younger age, to have a lifetime history of being heavier, and to have been heavier and more dissatisfied with their body at pretreatment, posttreatment, and at 5‐year follow‐up.ConclusionFive years after treatment for bulimia nervosa, approximately one half of the participants had changed substantially in weight. For those who had changed, weight loss was more common than weight gain. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 12–21, 2004.
Gabriella Milos, Anja Spindler, Ulrich Schnyder, et al. Incidence of severe anorexia nervosa in switzerland: 40 years of development. International Journal of Eating Disorders. 2004; 35(3):250–258
Authors: Milos Gabriella , Spindler Anja , Schnyder Ulrich , Martz Jan , Hoek Hans Wijbrand , Willi Jürg 
Published: June 2004

AbstractThe original article to which this Erratum refers was published in International Journal of Eating Disorders (2004) 35(3):250–258
Mechanistic Tuning of Hydrocarbon Oxidations with H2O2, Catalyzed by Hexacoordinate Ferrous Complexes
Authors: Mekmouche Yasmina , Ménage Stéphane , Pécaut Jacques , Lebrun Colette , Reilly Lee , Schuenemann Volker , Trautwein Alfred , Fontecave Marc 
Published: June 2004

AbstractA comparison of the catalytic properties of a series of FeIILXY complexes on oxidation reactions with H2O2, [L = N,N′‐bis(pyridin‐2‐yl‐methyl)‐N,N′‐bis(3,4,5‐trimethoxybenzyl)ethane‐1,2‐diamine] indicates that the lability of the X and Y ligands (Cl− or CH3CN) determines the nature of the oxidation pathway. The absence of a labile site in the complex, i.e. when X = Y = Cl−, causes the reaction to proceed via a Fenton pathway (generation of hydroxyl radicals, exclusively). The presence of two labile CH3CN ligands (X = Y = CH3CN) allows the catalysis to proceed through a metal‐based mechanism, whereas in the case of a complex with only one labile ligand (X = Cl− and Y = CH3CN), the reaction is less controlled by the metal. We wish to emphasize that the cleavage of the O−O bond in the Fe−OOH moeity, a key intermediate in the reaction, is different in the last two cases. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)