bluuebunny/crossref_metadata_2025_split huggingface dataset:
The behavioral origins of phylogenic responses and ontogenic habits
Authors: Stahlman W. David , Leising Kenneth J. 
Published: November 2023

AbstractAn examination of innate behavior and its possible origins suggests parallels with the formation of habitual behavior. Inflexible but adaptive responses—innate reflexive behavior, Pavlovian conditioned responses, and operant habits—may have evolved from variable behavior in phylogeny and ontogeny. This form of “plasticity‐first” scientific narrative was unpopular post‐Darwin but has recently gained credibility in evolutionary biology. The present article seeks to identify originating events and contingencies contributing to such inflexible but adaptive behavior at both phylogenic and ontogenic levels of selection. In ontogeny, the development of inflexible performance (i.e., habit) from variable operant behavior is reminiscent of the genetic accommodation of initially variable phylogenic traits. The effects characteristic of habit (e.g., unresponsiveness to reinforcer devaluation) are explicable as the result of a conflict between behaviors at distinct levels of selection. The present interpretation validates the practice of seeking hard analogies between evolutionary biology and operant behavior. Finding such parallels implies the validity of a claim that organismal behavior, both innate and learned, is a product of selection by consequences. A complete and coherent account of organismal behavior may ultimately focus on functional selective histories in much the same way evolutionary biology does with its subject matter.
Outcomes among patients with hepatorenal syndrome based on hospital teaching and transplant status: Analysis of 159 845 hospitalizations
Authors: Sohal Aalam , Chaudhry Hunza , Dukovic Dino , Kowdley Kris V. 
Published: November 2023

AbstractBackground and AimHepatorenal syndrome (HRS) is a life‐threatening complication of advanced liver disease. This study aimed to examine the impact of hospital teaching/transplant status and availability of liver transplantation on survival among hospitalized patients with HRS in the United States.MethodsPatients with HRS were identified from the national inpatient sample 2016–2019. Information was collected regarding patient demographics, hospital characteristics, liver disease etiology, presence of liver disease decompensations, Elixhauser comorbidities, and interventions. Patients were classified as being treated at three hospital groups: non‐teaching hospitals (NTHs), teaching non‐transplant centers (TNTCs), and teaching transplant centers (TTCs). The relationship between hospital teaching/transplant status and in‐hospital mortality and transplant‐free mortality was examined using multivariable linear and logistic regression analysis.ResultsA total of 159,845 patients met the criteria for HRS. Of these, 24% were admitted to NTHs, 50.8% to TNTCs, and 25.2% to TTCs. Admission to a TTC was independently associated with a lower mortality risk compared to admission to non‐TTCs (aOR = 0.75, 95% CI: 0.68–0.83, P <0.001). Patients at TTCs had a lower transplant‐free mortality risk than those at NTHs (aOR = 0.75, 95% CI: 0.67–0.83, P < 0.001). There was no significant difference in all‐cause or transplant‐free mortality between TNTCs and NTHs.ConclusionPatients with HRS admitted to TTCs have higher disease severity, but significantly improved outcomes compared to those admitted to NTHs. These data suggest opportunities for increased disease awareness and education among NTHs and support early referral for liver transplant evaluation among hospitalized patients with HRS.
Endoscopic papillectomy could be rewarding to patients with early stage duodenal ampullary carcinoma?
Authors: Suzuki Ko , Kurita Yusuke , Kubota Kensuke , Fujita Yuji , Tsujino Seitaro , Koyama Yuji , Tsujikawa Shintaro , Tamura Shigeki , Yagi Shin , Hasegawa Sho , Sato Takamitsu , Hosono Kunihiro , Kobayashi Noritoshi , Iwashita Hiromichi , Yamanaka Shoji , Fujii Satoshi , Endo Itaru , Nakajima Atsushi 
Published: November 2023

AbstractBackground/PurposeThere is currently no consensus on the use of endoscopic papillectomy (EP) for early stage duodenal ampullary adenocarcinoma. This study aimed to evaluate the feasibility of EP for patients with early stage duodenal ampullary adenocarcinoma.MethodsPatients who underwent EP for ampullary adenocarcinomas were investigated. Complete and clinical complete resection rates were evaluated. Clinical complete resection was defined as either complete resection or resection with positive or unknown margins but no cancer in the surgically resected specimen, or no recurrence on endoscopy after at least a 1‐year follow‐up.ResultsAdenocarcinoma developed in 30 patients (carcinoma in situ [Tis]: 21, mucosal tumors [T1a(M)]: 4, tumors in the sphincter of Oddi [T1a(OD)]: 5). The complete resection rate was 60.0% (18/30) (Tis: 66.7% [14/21], T1a[M]: 50.0% [2/4], and T1a[OD]: 40.0% [2/5]). The mean follow‐up period was 46.8 months. The recurrence rate for all patients was 6.7% (2/30). The clinical complete resection rates of adenocarcinoma were 89.2% (25/28); rates for Tis, T1a(M), and T1a(OD) were 89.4% (17/19), 100% (4/4), and 80% (4/5), respectively.ConclusionsEP may potentially achieve clinical complete resection of early stage (Tis and T1a) duodenal ampullary adenocarcinomas.
Advances in Neuroimaging and Multiple Post‐Processing Techniques for Epileptogenic Zone Detection of Drug‐Resistant Epilepsy
Authors: Yao Lei , Cheng Nan , Chen An‐qiang , Wang Xun , Gao Ming , Kong Qing‐xia , Kong Yu 
Published: November 2023

Among the approximately 20 million patients with drug‐resistant epilepsy (DRE) worldwide, the vast majority can benefit from surgery to minimize seizure reduction and neurological impairment. Precise preoperative localization of epileptogenic zone (EZ) and complete resection of the lesions can influence the postoperative prognosis. However, precise localization of EZ is difficult, and the structural and functional alterations in the brain caused by DRE vary by etiology. Neuroimaging has emerged as an approach to identify the seizure‐inducing structural and functional changes in the brain, and magnetic resonance imaging (MRI) and positron emission tomography (PET) have become routine noninvasive imaging tools for preoperative evaluation of DRE in many epilepsy treatment centers. Multimodal neuroimaging offers unique advantages in detecting EZ, especially in improving the detection rate of patients with negative MRI or PET findings. This approach can characterize the brain imaging characteristics of patients with DRE caused by different etiologies, serving as a bridge between clinical and pathological findings and providing a basis for individualized clinical treatment plans. In addition to the integration of multimodal imaging modalities and the development of special scanning sequences and image post‐processing techniques for early and precise localization of EZ, the application of deep machine learning for extracting image features and deep learning‐based artificial intelligence have gradually improved diagnostic efficiency and accuracy. These improvements can provide clinical assistance for precisely outlining the scope of EZ and indicating the relationship between EZ and functional brain areas, thereby enabling standardized and precise surgery and ensuring good prognosis. However, most existing studies have limitations imposed by factors such as their small sample sizes or hypothesis‐based study designs. Therefore, we believe that the application of neuroimaging and post‐processing techniques in DRE requires further development and that more efficient and accurate imaging techniques are urgently needed in clinical practice.Level of Evidence5Technical EfficacyStage 2
Effects of inhibition of Nav1.3, Nav1.7, and Nav1.8 channels on pain‐related behavior in Speke's hinge‐back tortoise (Kinixys spekii)
Authors: Makau Christopher M. , Towett Philemon K. , Kanui Titus I. , Abelson Klas S. P. 
Published: November 2023

AbstractComparative studies using reptiles as experimental animals in pain research could expand our knowledge on the evolution and adaptation of pain mechanisms. Currently, there are no data reported on the involvement of voltage‐gated sodium ion channels on nociception in reptiles. The aim of this study was to investigate the involvement of Nav1.3, Nav1.7, and Nav1.8 ion channels in nociception in Speke's hinge‐back tortoise. ICA 121341 (selective blocker for Nav1.1/Nav1.3), NAV 26 (selective blocker for Nav1.7), and A803467 (selective blocker for Nav1.8) were used to investigate the involvement of Nav1.3, Nav1.7, and Nav1.8, respectively. The chemicals were administered intracoelomically thirty minutes before the start of nociceptive tests. ICA 121341 did not cause a significant decrease in the time spent in pain‐related behavior in all the nociceptive tests. NAV 26 and A8034667 caused a statistically significant decrease in the mean time spent in pain‐related behavior in the formalin and capsaicin tests. Only A803467 caused a statistically significant increase in the mean latency to pain‐related behavior in the hot plate test. NAV 26 and A803467 had no observable side effects. In conclusion, Nav1.7 and Nav1.8 are involved in the processing of chemically induced inflammatory pain in Speke's hinge back tortoise. In addition, Nav1.8 are also significantly involved in the development of thermal‐induced pain‐related behavior in this species of reptile. However, our results do not support the involvement of Nav1.3 on the development of chemical or thermal induced pain‐related behavior in the Speke's hinge back tortoise.
Subacute postoperative atrial fibrillation after heart surgery: Incidence and predictive factors in cardiac rehabilitation
Authors: Rizza Vincenzo , Maranta Francesco , Cianfanelli Lorenzo , Cartella Iside , Maisano Francesco , Alfieri Ottavio , Cianflone Domenico 
Published: November 2023

AbstractBackgroundPostoperative atrial fibrillation (POAF) is the most common arrhythmia following cardiac surgery (CS). It may occur between the 1st and the 4th postoperative day as acute POAF or between the 5th and the 30th as subacute (sPOAF). sPOAF is associated with higher thromboembolic risk, which consistently increase patients' morbidity. Neutrophil‐to‐lymphocyte ratio (NLR) is a low‐cost inflammatory index proposed as possible POAF predictor. Identification of patients' risk categories might lead to improved postoperative outcomes.MethodsThe aim was to assess the incidence of sPOAF and to identify possible predictors in patients performing cardiovascular rehabilitation (CR) after CS. A single‐center cohort study was performed on 737 post‐surgical patients admitted to CR on sinus rhythm. Continuous monitoring with 12‐lead ECG telemetry was performed. We evaluated the predictive role of anamnestic, clinical, and laboratory data, including baseline NLR.ResultsSubacute POAF was documented in 170 cases (23.1%). At the multivariate analysis, age (OR 1.03; p = .001), mitral valve surgery (OR 1.77; p = .012), acute POAF (OR 2.97; p < .001), and NLR at baseline (OR 1.13; p = .042) were found to be independent predictive factors of sPOAF following heart surgery.ConclusionssPOAF is common after CS. Age, mitral valve procedures, acute POAF, and preoperative NLR were proved to increase sPOAF occurrence in CR. NLR is an affordable and reliable parameter which might be used to qualify the risk of arrhythmias at CR admission. Identification of new predictors of postoperative atrial fibrillation may allow to improve patients' prognosis.
The influence of dynamic resources and stable isotope incorporation rates on aquatic consumer trophic position estimation
Authors: Feddern Megan L. , Nielsen Jens M. , Essington Timothy E. , Holtgrieve Gordon W. 
Published: November 2023

AbstractA key assumption in trophic position (TP) estimation using stable isotope analysis is that consumers are in isotopic equilibrium with their resources. Here, we assess the degree to which time‐varying resource dynamics and isotope incorporation rates of consumers influence consumer TP estimates across multiple trophic levels and aquatic ecosystems. We constructed a first‐order kinetics model to explore consumer stable isotope incorporation rates and modeled the effect on TP calculations using bulk and compound‐specific stable isotope data from previous experimental and observational studies. We found TP estimates of higher trophic level consumers are less accurate than lower trophic level consumers when applying bulk stable isotope analysis (BSIA) and using particulate organic matter as the stable isotope baseline. The accuracy of TP estimates depended on the time‐varying dynamics of the stable isotope baseline. Tertiary consumers had the highest TP estimation error, and this error was not eliminated by sampling tissues with fast incorporation rates (i.e., blood) in the tertiary consumer. Compound‐specific stable isotope analysis (CSIA) of individual amino acids was more accurate in estimating TP for all consumers and ecosystems compared to BSIA. Our analysis confirms that consideration for the dynamic nature of stable isotope ratios is necessary for accurate TP estimates. Finally, we show how first‐order kinetics models can provide a useful framework for integrating prey and consumer incorporation rates in stable isotope studies to improve TP estimates.
Intra‐Cavity Laser Manipulation of High‐Dimensional Non‐Separable States
Authors: Hai Lan , Zhang Zhichao , Liu Shilong , Li Lang , Zhou Zhiyuan , Wang Qing , Gao Yanze , Gao Chunqing , Shen Yijie , Fu Shiyao 
Published: November 2023

AbstractNon‐separable states of structured light have the analogous mathematical forms with quantum entanglement, which offer an effective way to simulate quantum process. However, the classical multi‐partite non‐separable states analogue to multi‐particle entanglements can only be controlled by bulky free‐space modulation of light through coupling multiple degrees of freedom (DoFs) with orbital angular momentum (OAM) to achieve high dimensionality and other DoFs to emulate multi‐parties. In this paper, a scheme is proposed to directly emit multi‐partite non‐separable states from a simple laser cavity to mimic multi‐particle quantum entanglement. Through manipulating three DoFs as OAM, polarization, and wavevector inside a laser cavity, the eight‐dimensional (8D) tripartite states and all Greenberger‐Horne‐Zeilinger (GHZ)‐like states can be generated and controlled on demand. In addition, an effective method is proposed to perform state tomography employing convolutional neural network (CNN), for measuring the generated GHZ‐like states with highest fidelity up to 95.11%. This work reveals a feasibility of intra‐cavity manipulation of high‐dimensional multipartite non‐separable states, opening a compact device for quantum‐classical analogy and paving the path for advanced quantum scenarios.
Manipulating the Exciton Dynamics in a MoS2/WS2 Heterobilayer with a Si/Au Nanocavity
Authors: Liu Shimei , Li Shulei , Mao Yuheng , Lin Zhenxu , Panmai Mingcheng , Li Guang‐Can , Zhou Lidan , Lan Sheng 
Published: November 2023

AbstractManipulating the exciton dynamics in a heterobilayer (HB) composed of two transition metal dichalcogenides (TMDCs) is important in the development of photonic/plasmonic devices based on TMDC HBs. Here, the realization of such a manipulation in a MoS2/WS2 HB is reported by using a Si/Au hybrid nanocavity composed of a Si nanoparticle and an Au film, which is manifested in the modification in the photoluminescence (PL) of the embedded MoS2/WS2 HB. It is shown that a transition from PL quenching to PL enhancement can be achieved by adjusting the diameter of the Si nanoparticle, which modifies the plasmon resonance supported by the Si/Au nanocavity. More interestingly, it is demonstrated that the enhancement factor can be manipulated by shifting the exciton/trion resonance close to or far away from the plasmon resonance by simply increasing the laser power. It is revealed that the manipulation is realized by effectively controlling the strain and Purcell effects induced by the Si/Au nanocavity. A PL enhancement factor as large as ≈187 in the MoS2/WS2 HB at a high laser power is observed. The findings suggest the potential applications of dielectric‐metal hybrid nanocavities in the manipulation of the exciton dynamics in TMDC HBs and the development of novel plasmonic devices.
Suspension Photopolymerization of Methyl Methacrylate and ATRP Grafting of Thermo‐Responsive Polymers Using a Perylediimide Derivative Photoinitiator
Authors: Diacon Aurel , Rizea Florica , Mocanu Alexandra , Dinescu Adrian , Stavarache Cristina , Jinga Luiza Izabela , Mihăilescu Cristian N. , Rusen Edina 
Published: November 2023

AbstractThe first aim of this study is to develop a photo‐ATRP process using methyl methacrylate (MMA) by employing a novel perylenediimide derivative (PDI) as photoinitiator. The analysis of the MMA photopolymerization process kinetics is performed in solution and in bulk, demonstrating control over the reaction progress even if the polymerizations display a slow initiation step. The photo‐ATRP process for MMA in suspension is also developed and the obtained PMMA particles are further used to reinitiate the ATRP polymerization of thermoresponsive polymers (different molecular weights poly(ethylene glycol) methyl ether methacrylate and poly(N‐isopropylacrylamide)) (PNIPAM) in solution and surface‐initiated processes. The synthesized polymers by surface‐initiated process display a bimodal molecular weight distribution with a clear modification of the signal areas ratio depending on the grafted monomer and on the reaction conditions. The grafting process can take place on the surface of the polymer particles (Mn2), or it can also involve polymer chains located further at the interior of the polymer particles (Mn1). The lower critical solution temperature (LCST) transition is demonstrated for the PNIPAM functionalized polymer particles.
Mechanical Recycling of Waste PLA Generated From 3D Printing Activities: Filament Production and Thermomechanical Analysis
Authors: Agbakoba Victor Chike , Webb Nicholas , Jegede Emmanuel , Phillips Russell , Hlangothi Shanganyane Percy , John Maya Jacob 
Published: November 2023

AbstractThere is a growing need to address waste generated from Fused Filament Fabrication (FFF) 3D printing activities. This study explores the mechanical recycling of waste polylactic acid (PLA) accumulated from failed 3D printing operations and PLA biocomposite filaments containing nanocellulose fibres. FFF 3D printable filaments were produced via melt mixing and extrusion of virgin PLA containing varying amounts of waste PLA. The chemical, thermal and thermomechanical characterisation of each specimen was evaluated using Fourier‐transform infrared spectroscopy (FTIR), simultaneous thermal analysis (SDT), dynamic mechanical analysis (DMA), and uniaxial tensile analysis (UTA). A desktop FFF 3D printer was used to fabricate UTA and DMA test specimens. The thermal stability of the filament specimens containing waste derived from the failed 3D prints were comparable with that of the commercial filaments. However, a 11% decrease in the onset of thermal degradation is observed for the filament containing waste biocomposites. The specimens containing waste PLA exhibited higher crystallinity and storage modulus. UTA results revealed similar tensile strength and % elongation, except for the specimen containing 50% waste PLA which exhibited a 29% decrease in tensile strength. This work successfully demonstrates mechanical recycling as a viable waste management strategy for waste materials generated during FFF 3D printing.
N, S‐Codoped Carbon Dots‐Based Reusable Solvatochromic Organogel Sensors for Detecting Organic Solvents
Authors: Jeong Gwajeong , Kim Taewook , Park Seong Dae , Yoo Myong Jae , Park Chan Ho , Yang Hyunseung 
Published: November 2023

AbstractThe visualization and analysis of organic solvents using fluorescent sensors are crucial, given their association with environmental safety and human health. Conventional fluorescent sensors are typically single‐use sensors and they often require sophisticated measurement instruments, which limits their practical and diverse applications. Herein, we develop solvatochromic nitrogen and sulfur codoped carbon dots (NS‐CDs)‐based organogel sensors that display color changes in response to different solvents. NS‐CDs are synthesized using a solvothermal method to produce monodispersed particles with exceptional solubility in various organic solvents. NS‐CDs exhibit distinct photoluminescent emission spectra that correlate with the solvent polarity, and the solvent‐dependent photoluminescent mechanism is investigated in detail. To highlight the potential application of solvatochromic NS‐CDs, portable and low‐cost NS‐CDs‐embedded organogel sensors are fabricated. These sensors exhibit highly robust solvatochromic performance despite repeated solvent switches, thus ensuring consistent and reliable measurements in practical applications. This study provides valuable insights into the solvatochromism of carbon dots and opens up new avenues for designing real‐time organic solvent sensing platforms.
Application of a structured decision‐making process in cryospheric hazard planning: Case study of Bering Glacier surges on local state planning in Alaska
Authors: Abdel‐Fattah Dina , Danielson Mats , Ekenberg Love , Hock Regine , Trainor Sarah 
Published: November 2023

AbstractSurging glaciers are glaciers that experience rapidly accelerated glacier flow over a comparatively short period of time. Though relatively rare worldwide, Alaska is home to the largest number of surge‐type glaciers globally. However, their impact on the broader socioecological system in the state is both poorly understood and under‐researched, which poses a challenge in developing appropriate sustainability decisions in Alaska. We investigated how the surge patterns of the Bering Glacier in Alaska have potentially devastating effects on the local ecological biodiversity of its watershed via a structured decision‐making analysis of the different possible consequences. Specifically, this analysis was conducted to explore the various outcomes of a Bering Glacier surge particularly if humans have an increased presence near the glacier due to the area potentially becoming a state park. This work explored the benefits of applying a risk and decision analytical framework in a cryosphere context, to better understand the socioeconomic impact of glacier surges. This is a novel approach in which a decision analysis tool was used to better understand an environmental sustainability challenge, offering an innovative method to support the achievement of the United Nations Sustainability Development Goals in Alaska. We therefore emphasise the need for integrated biophysical and socioeconomic analyses when it comes to understanding glacier hazards. Our research highlights the importance of understanding and researching biophysical changes as well as using a structured decision‐making process for complicated hazard planning scenarios, exemplified via glaciated regions in Alaska, in order to create adaptation strategies that are sustainable and encompass the range of possible outcomes.