bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interventional treatment of giant tracheal lymphoma under rigid bronchoscopy: A case report and literature review
Authors: Zhang Longju , Yang Jiao , Wang Ju , Wu Jiahao , Shen Sulu , Deng Chuwei 
Published: January 2024

Introduction:
Lymphoma can appear in all parts of the body and present with different symptoms. However, bronchial lymphoma is rare and can be misdiagnosed as airway malignancy or lung disease.
Patient: An older adult woman with tracheal lymphoma experienced severe breathing difficulties, and chest computed tomography indicated severe narrowing of the airway. She did not respond to repeated antibiotic treatment, and she was eventually diagnosed with lymphoma based on pathology after surgical removal of the tumor.

Diagnosis:
The patient received a diagnosis of thoracic tracheal stenosis due to intratracheal inflammatory granulomatous lesions or a tumor.

Interventions:
Treatment involved the use of a high-frequency electrotome, freezing, and argon plasma coagulation.

Outcomes:
The patient reported improvements in dyspnea, cough, and other symptoms after the operation. The pathological results confirmed follicular lymphoma. Reexamination by fiberbronchoscopy indicated that the degree of stenosis in the middle and upper tracheal segments was significantly reduced following interventional therapy.

Conclusion:
Endoscopic interventional therapy can be an effective treatment for tracheal lymphoma.
Nasal spindle cell tumor: A case report and literature review
Authors: Feng Yu , Yu Yunbei , Meng Kai , Li Maocai , Jia Guotao , Du Yongya , Liu Siyu , Gong Lili , Li Lianqing 
Published: January 2024

Background:Spindle cell tumors are rare and can occur in any organ or tissue. Due to their rarity the clinicopathological features and diagnostic protocols have not been adequately studied. However, it has become necessary to develop differential diagnosis of spindle cell tumors. Here, we report a case of a nasal spindle cell tumor diagnosed at our hospital in attempt to contribute to this gap in literature.Key points from the case:A male in his 30s was admitted to our hospital with nasal obstruction that had persisted for several years. Electronic fibrolaryngoscopy revealed a smooth neoplasm within the nasal cavity.Main lessons to be learned from this case report:The results of this case emphasize that spindle cell tumors have large morphological variations, and it is difficult to determine the origin of tumor cells using hematoxylin and eosin staining alone. Therefore, it is necessary to improve the immunohistochemistry and combine it with clinical symptoms to diagnose the disease.
Effects of cervical stabilization with visual feedback on craniovertebral angle and proprioception for the subjects with forward head posture
Authors: Goo Bon Wook , Oh Jin Hee , Kim Ju Sang , Lee Mi Young 
Published: January 2024

Background:
This study aimed to identify the effect of cervical stabilization exercise with visual feedback on the craniovertebral angle and proprioception in subjects with forward head posture.

Methods:
Thirty healthy adults were recruited in the study. Participants were randomly assigned to the stabilization exercise with visual feedback (SE-VF) group (N = 15) or stabilization exercise group (N = 15). The SE-VF group performed cervical stabilization exercise while sitting on a chair without a backrest and checking their side profile in real-time via a monitor 3-m away. The stabilization exercise group performed the same cervical stabilization exercise as the SE-VF group but without visual feedback. Craniovertebral angle (CVA) was measured to quantify forward head posture, and the proprioception of the subjects was evaluated.

Results:
There was a significant interaction between group and time in CVA and proprioception (P < .05). Additionally, there was no significant difference pre-intervention between the groups (P > .05); however, there was a significant difference post-intervention (P < .05) in CVA and proprioception.

Conclusion:
The findings of this study showed that the cervical stabilization exercise with visual feedback was effective for the proprioception of subjects. Moreover, the results suggest that visual feedback is effective in cervical stabilization exercise.
Pain relief effect of angiopuncture therapy on patients with postoperative pain: A clinical trial
Authors: Han Rong , Feng Wenxian , Guo Chunxia , Ding Zhiwei , Hu Jinlian 
Published: January 2024

Background:
The objective of this study is to study the pain relief effects of angiopuncture therapy in patients with postoperative pain.

Methods:
Forty-one patients were randomly selected based on the inclusion and exclusion criteria. Doppler imaging was performed to locate the cutaneous perforator. Angiopuncture was performed on the first postoperative day. A Numerical Rating Scale was used to evaluate the degree of pain before and after angiopuncture. Utilizing the paired t test or Wilcoxon signed rank test, all pre- and post-data were examined, and further subgroup analysis based on time was performed.

Results:
Variance analysis revealed a significant difference before and after angiopuncture (P < .05). The results of the subgroup analysis showed the pain-relieving effect of angiopuncture for postoperative pain patients at the time points of 6 hours, 12 hours, 24 hours, 48 hours, and 72 hours was apparent (P < .05).

Conclusion:
The angiopuncture therapy approach may assist in pain relief in patients with postoperative pain.
Efficacy of magnetic therapy for osteoporotic patients: A meta-analysis of randomized controlled studies
Authors: Jiang Feng , Xie Xianping , Pang Xianlun , Zheng Li 
Published: January 2024

Background:
Magnetic therapy may have some potential in treating osteoporosis, and this meta-analysis aims to study the efficacy of magnetic therapy for osteoporotic patients.

Methods:
We have searched several databases including PubMed, EMbase, Web of Science, EBSCO and Cochrane library databases, and selected the randomized controlled trials comparing the efficacy of magnetic therapy for osteoporotic patients. This meta-analysis was conducted using the random-effect or fixed-effect model based on the heterogeneity.

Results:
Five randomized controlled trials were included in this meta-analysis. Compared with sham procedure in osteoporotic patients, magnetic therapy was associated with significantly increased bone mineral density (standard mean difference [SMD] = 2.39; 95% confidence interval [CI] = 0.27–4.51; P = .03), decreased pain scores (mean difference [MD] = −0.86; 95% CI = −1.04 to −0.67; P < .00001), and calcium (MD = −0.61; 95% CI = −0.92 to −0.29; P = .0002), but revealed no influence on phosphate (MD = 0.07; 95% CI = −0.30 to 0.44; P = .71), osteocalcin (SMD = 0.65; 95% CI = −2.87 to 4.17; P = .72), or ALP (SMD = −0.43; 95% CI = −0.92 to 0.07; P = .09).

Conclusions:
Magnetic therapy may be effective for the treatment of osteoporotic patients.
A case report of integrating Chinese and Western medicine: A new era in the treatment of stiff person syndrome
Authors: Lu Xiaohui , Hong Du , Wu Wenshuo , Zhang Liping , Qiu Changlin 
Published: January 2024

Rationale:
At present, there are limitations to the treatment of stiff person syndrome (SPS). Current treatments are still ineffective or financially burdensome for some patients, so it is imperative to explore more appropriate treatments for patients. This is a case report of a SPS with a more significant effect of combined Chinese and Western medicine, which may provide new treatment ideas for other patients.

Patient concerns:
This patient presented with episodes of stiffness and pain in the lower back and lower extremities. His electromyography shows continued activation of normal motor units in the paraspinal and abdominal muscles. However, relevant laboratory tests including glutamic acid decarboxylase antibody and Amphiphysin antibody were negative. After a period of treatment including clonazepam, baclofen, prednisone and intravenous immunoglobulin, this patient experiences a shortened maintenance period of medication, accompanied by symptoms such as emotional anxiety and cognitive decline, which severely affects his life.

Diagnoses:
This patient was diagnosed with SPS.

Interventions:
In May 2022 the patient decided to combine Chinese medicine for simultaneous treatment.

Outcomes:
During the period of simultaneous treatment with Chinese and Western medicine, the patient experienced remission of clinical symptoms, reduction of concomitant symptoms and improved quality of life.

conclusion:
A combination of Western and Chinese medicine was effective in relieving this patient pain and stiffness and reducing the patient anxiety. Combined Chinese and Western medicine treatment may be able to bring better results to more patients with stiff person syndrome.
Sudden diffuse spasm of multiple coronary arteries: A case report
Authors: Cai Hui , Chen Shuxia , Wang Dongxiao 
Published: January 2024

Rationale:
Diffuse multivessel coronary artery spasm (DMV-CAS) was defined as a severe and reversible diffuse spasm occurring in more than 2 major coronary arteries, which is rare in clinical practice. Due to a wide lesion scope, DMV-CAS often occurs in the form of complications. It is not easy to be clinically diagnosed because it is too brief to be caught. Here, we report a rare case of spontaneous subtotal occlusion of 3 major coronary arteries induced by Vasalva action, which was confirmed in real-time by CAG.

Patient concerns:
A 68-year-old man had sudden chest pain after forced defecation during hospitalization. The electrocardiogram showed transient ST segment elevation of the inferior wall lead, inversion of the anterior wall, and lateral wall leads T waves. Emergency CAG revealed elongated vessel beds in 3 coronary arteries and multiple diffuse stenosis, but none of the coronary arteries were completely occlusive.

Diagnoses:
Diagnoses of DMV-CAS were made based on CAG findings and postmedication response.

Interventions:
Nitroglycerin was administered in the coronary arteries. The anti-vasospasm, antiplatelet aggregation and lipid-regulating drugs were administered orally.

Outcomes:
The patient was discharged on the 7th day with complete resolution of symptoms and normalization of the electrocardiography findings. No ischemic events occurred during a follow-up for 5 months.

Lessons:
This case highlights the identification of multivessel diffuse coronary spasm and acute myocardial infarction, and the prevention of CAS triggers, which requires the attention of clinicians.
Case report: A case of high virulence and multidrug resistant Klebsiella pneumoniae liver abscess in Ningxia, China
Authors: Wang Liangfang , Li Gang , Hou Xiaohui , Feng Lijun , Shi Zhiyun 
Published: January 2024

Rationale:
Highly virulent multidrug-resistant Klebsiella pneumoniae (KP) is becoming more and more common in clinical practice, especially the rise of carbapenem-resistant KP in clinical practice, resulting in the emergence of KP liver abscess in Ningxia, China. For the prognosis of liver abscess patients, it is particularly important to identify the types of pathogens and identify antibiotics that are sensitive to the pathogens.

Patient concerns:
A 73-year-old man from China presents to our hospital with abdominal pain, jaundice and fever. Patients have no obvious cause of abdominal pain, abdominal distension, and abdominal pain is persistent. Abdominal examination showed hepatomegaly, no tenderness 2 cm from the right costal margin, abdominal distension and other general examinations did not have obvious abnormalities. He had no history of hypertension and diabetes, ERCP was performed for cholangiocarcinoma 1 year before the current visit, and no significant complications occurred.

Diagnoses:
His initial diagnosis was obstructive cholangitis, and computed tomographic images and liver drainage fluid bacterial culture and genetic polymerase chain reaction tests later determined that the patient had KP liver abscess.

Interventions:
Drainage by liver catheter and antibiotic treatment for 7 weeks.

Outcomes:
The patient liver abscess is basically gone.

Lession:
It is particularly important to optimize the diagnosis of liver abscess pathogens for timely and effective treatment of patients.
Case report: Blood pressure variation during cardiopulmonary bypass in a patient with multiple sclerosis
Authors: Helms Florian , Rümke Stefan , Schill Bettina , Kühn Christian 
Published: January 2024

Introduction and importance:
Multiple sclerosis is known to be associated with both sympathetic and parasympathetic cardiovascular autonomic dysregulation. Thus, patients with multiple sclerosis comorbidity represent a potentially challenging patient population in cardiac surgery, especially in on-pump operations. Despite this, very little is known about the hemodynamics during cardiopulmonary bypass and the optimal perfusion strategy for patients with multiple sclerosis undergoing cardiac operations.

Case presentation:
In this report, the authors describe a patient with relapsing-remitting multiple sclerosis, who underwent successful triple valve operation for aortic and mitral stenosis and tricuspid valve insufficiency. Distinct blood pressure variations in form of temporary pressure dips were noted during total cardiopulmonary bypass time as well as during the reperfusion period.

Clinical discussion:
Pressure variations were not attributable to surgical, pharmacological or perfusion-related manoeuvres. Thus, they most likely represent symptoms of cardiovascular autonomic dysregulation manifesting during cardiopulmonary bypass. In this patient, blood pressure variations terminated spontaneously and remained within an acceptable range without external correction.

Conclusions:
When treating patients with multiple sclerosis comorbidity, the potential pressure variability due to cardiovascular autonomic dysregulation should be taken into consideration to avoid increased blood pressure volatility due to overcorrection or undercorrection during cardiopulmonary bypass.
Three-dimensional imaging evaluation of facial swelling after orthognathic surgery with compression and Kinesio taping therapy: a randomized clinical trial
Authors: Nakao Hiroaki , Hasegawa Shogo , Tomimatsu Mai , Sasaki Jun , Yamamoto Satoshi , Watanabe Satoshi , Miyabe Satoru , Terasawa Fumitaka , Miyachi Hitoshi , Goto Mitsuo 
Published: January 2024

Background
Postoperative swelling is a common complication of orthognathic surgery. The authors used three-dimensional (3D) image analysis and body surface temperature to determine the effects of compression taping (CT) and Kinesio taping (KT) by the epidermis, dermis, and fascia method (EDF-KT) on postoperative swelling.

Materials and methods:
The authors conducted a prospective, parallel-group, randomized controlled trial. Among the 162 patients diagnosed with jaw deformity and who underwent orthognathic surgery from August 2020 to October 2022, 105 patients (men: 36, women: 69, mean age: 28.27±8.92) underwent Le Fort type I + sagittal split ramus osteotomy (SSRO) or SSRO and were included in this study. Patients were randomly divided into three groups: EDF-KT group (n=31), CT group (n=41), and no tape group (control group, n=30). All taping was performed immediately postoperatively and removed on postoperative day (POD) 5. Three-dimensional images of the participants’ faces were obtained preoperatively and at PODs 3, 7, 30, and 90 using a hand-held 3D imaging system and infrared thermography.

Results:
No significant difference was observed in postoperative swelling and postoperative body surface temperature between the groups at each time point. The CT group showed a trend towards reduced swelling on PODs 3 and 7 and a trend toward residual swelling on POD 90. The EDF-KT group showed a trend towards an increase in postoperative body surface temperature.

Conclusion:
CT taping may not be appropriate for postoperative swelling control, suggesting that EDF-KT may affect body surface temperature. Further validation of the efficacy of KT for jaw deformities is needed.
Current use of intraoperative ultrasound in modern liver surgery
Authors: Chu Kai-Jian , Kawaguchi Yoshikuni , Hasegawa Kiyoshi 
Published: January 2024

Abstract
Ultrasound plays an important role not only in preoperative diagnosis but also in intraoperative guidance for liver surgery. Intraoperative ultrasound (IOUS) has become an indispensable tool for modern liver surgeons, especially for minimally invasive surgeries, partially substituting for the surgeon's hands. In fundamental mode, Doppler mode, contrast enhancement, elastography, and real-time virtual sonography, IOUS can provide additional real-time information regarding the intrahepatic anatomy, tumor site and characteristics, macrovascular invasion, resection margin, transection plane, perfusion and outflow of the remnant liver, and local ablation efficacy for both open and minimally invasive liver resections. Identification and localization of intrahepatic lesions and surrounding structures are crucial for performing liver resection, preserving the adjacent vital vascular and bile ducts, and sparing the functional liver parenchyma. Intraoperative ultrasound can provide critical information for intraoperative decision-making and navigation. Therefore, all liver surgeons must master IOUS techniques, and IOUS should be included in the training of modern liver surgeons. Further investigation of the potential benefits and advances in these techniques will increase the use of IOUS in modern liver surgeries worldwide. This study comprehensively reviews the current use of IOUS in modern liver surgeries.
The health equity implications of the Health Resources and Services Administration's Ryan White HIV/AIDS Program
Authors: Goyal Ravi , Hotchkiss John , Gilman Boyd , Klein Pamela W. , Mills Robert J. , Starling Jennifer , Martin Natasha K. , Patton Thomas , Cohen Stacy M. , Cheever Laura 
Published: January 2024

Objective:
Investigate the role of the Ryan White HIV/AIDS Program (RWHAP) – which funds services for vulnerable and historically disadvantaged populations with HIV – in reducing health inequities among people with HIV over a 10-year horizon.

Design:
We use an agent-based microsimulation model to incorporate the complexity of the program and long-time horizon.

Methods:
We use a composite measure (the Theil index) to evaluate the health equity implications of the RWHAP for each of four subgroups (based on race and ethnicity, age, gender, and HIV transmission category) and two outcomes (probability of being in care and treatment and probability of being virally suppressed). We compare results with the RWHAP fully funded versus a counterfactual scenario, in which the medical and support services funded by the RWHAP are not available.

Results:
The model indicates the RWHAP will improve health equity across all demographic subgroups and outcomes over a 10-year horizon. In Year 10, the Theil index for race and ethnicity is 99% lower for both outcomes under the RWHAP compared to the non-RWHAP scenario; 71–93% lower across HIV transmission categories; 31–44% lower for age; and 73–75% lower for gender.

Conclusion:
Given the large number of people served by the RWHAP and our findings on its impact on equity, the RWHAP represents an important vehicle for achieving the health equity goals of the National HIV/AIDS Strategy (2022–2025) and the Ending the HIV Epidemic Initiative goal of reducing new infections by 90% by 2030.
Prospective Sensory Outcomes for Targeted Nipple Areola Complex Reinnervation (TNR) in Gender-Affirming Double Incision Mastectomy with Free Nipple Grafting
Authors: Remy Katya , Packowski Kathryn , Alston Chase , Kozanno Liana N. , Carruthers Katherine H. , Tomczyk Eleanor G. , Winograd Jonathan M. , Austen William G. , Valerio Ian L. , Gfrerer Lisa 
Published: January 2024

Objective:
This study analyses the anatomy and sensory outcomes of targeted nipple areola complex reinnervation (TNR) in gender-affirming double incision mastectomy with free nipple grafting (FNG).

Background:
TNR is a novel technique to preserve and reconstruct intercostal nerves (ICN) to improve postoperative sensation. There is little evidence on relevant anatomy and outcomes.

Methods:
25 patients were prospectively enrolled. Data included demographics, surgical technique, and axon/fascicle counts. Quantitative sensory evaluation using monofilaments and qualitative patient reported questionnaires were completed preoperatively, and at one, three, six, nine and twelve months postoperatively.

Results:
50 mastectomies were performed. Per mastectomy, the median number of ICN found and used was 2 (1-5). Axon and fascicle counts were not significantly different between ICN branches (P>0.05). BMI ≥30 kg/m2 and mastectomy weight ≥800 g were associated with significantly worse preoperative sensation (P<0.05). Compared to preoperative values, NAC sensation was worse at 1 month (P<0.01), comparable at 3 months (P>0.05), and significantly better at 12 months (P<0.05) postoperatively. Chest sensation was comparable to the preoperative measurements at 1 and 3 months (P>0.05), and significantly better at 12 months (P<0.05) postoperatively. NAC sensation was significantly better when direct coaptation was performed compared to use of allograft only (P<0.05), and with direct coaptation of ≥2 branches compared to direct coaptation of a single branch (P<0.05). All patients reported return of nipple and chest sensation at one year postoperatively and 88% reported return of some degree of erogenous sensation.

Conclusion:
TNR allows for restoration of NAC and chest sensation within 3 months postoperatively. Use of multiple ICN branches and direct coaptation led to the best sensory outcomes.
Artificial Intelligence to Predict Quality-of-Life Outcomes for Vascular Intervention of the Leg
Authors: Brothers Thomas E , Baliga Prabhakar 
Published: January 2024

BACKGROUND:
Artificial intelligence (AI) tools created to enhance decision-making may have a significant impact on treatment algorithms for peripheral arterial disease (PAD). A Markov-based AI model was developed to predict optimal therapy based on maximization of calculated quality of life (cQoL), a patient-centered system of assessment designed to report outcomes directly linked to health-related quality of life.

STUDY DESIGN:
The AI model was prospectively interrogated immediately after individual interventions for PAD over a 12-year period to test predictive performance. Patient cQoL was determined at each patient follow-up visit.

RESULTS:
A total of 1,143 consecutive patients were evaluated, with a median follow-up of 18 months. Observed mean annualized cQoL was higher than predicted by the model (0.85 ± 0.38 vs 0.79 ± 0.18, p < 0.0001). Of 5 potential clinical outcomes, the AI model correctly predicted final status in 71.3% of patients, with insignificant model performance deterioration over time (−0.15% per month, r = −0.49, p = 0.063). The chance of having the condition predicted by the model was 0.57 ± 0.32, compared with a theoretical maximum of 0.70 ± 0.19 (p < 0.0001, mean ratio 0.79). The AI model performed better in patients with claudication than limb-threatening ischemia (75.5% vs 63.6%, p = 0.014) but equally well for open or endovascular intervention (69.8% vs 70.5%, p = 0.70). Graft or artery patency and amputation-free survival were better for patients with claudication and those treated with endovascular techniques.

CONCLUSIONS:
AI can successfully predict treatment for PAD that maximizes patient quality of life in most cases. Future application of AI incorporating better estimates of patient anatomic and physiological risk factors and refinement of model structure should further enhance performance.