bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formulation Development and Evaluation of Dry Adsorbed Nanoparticles of Curcumin and Piperine Dual Drug Loaded Nanostructured Lipid Carriers
Authors: Hirlekar Rajashree , Bhairy Srinivas , Momin Alfiha 
Published: November 2023

Purpose: The present study was aimed at preparing stable dry adsorbed nanoparticles (DANs) of curcumin (CUR) and piperine (PIP) loaded nanostructured lipid carriers (NLCs).
Methods: CUR and PIP-loaded NLCs (CP NLCs) were prepared by modified hot-melt emulsification using precirol ATO5 (PRE) as solid lipid, labrafac lipophile WL1349 (LAF) as liquid lipid, and a combination of tween 80 (T80) with gelucire 50/13 (G50/13) as surfactants. The NLCs system was subjected to physical stability, particle size, zeta potential, thermal behaviour, crystallinity study and in-vitro drug release. Further, an evaporative drying technique converted the NLC system into stable DANs by adsorbing onto mannitol (Pearlitol 200SD). The DANs were characterized for redispersion properties, particle size, flow properties and in-vitro drug release. The stability studies were carried out for 30 days.
Results: The optimized CP NLCs were of imperfect type and had a mean particle size of 248.5 ± 12.8 nm (size distribution of 0.216 ± 0.021), a zeta potential of -9.03 ± 0.53 mV, an entrapment efficiency (EE) of 99.80 ± 0.21% (CUR), 100.05 ± 0.07% (PIP) with a drug recovery of 99.70 ± 0.21% (CUR) and 100.36 ± 0.12% (PIP). The X-ray diffraction pattern and endothermic peaks confirmed the encapsulation of actives in lipid matrices. The in-vitro drug release showed controlled release for 24 h. The optimized DANs led to maximum redispersion and retained a particle size of 268.4 ± 23.1 nm (distribution 0.235 ± 0.037) with controlled release similar to CP NLCs. The CP NLCs DANs showed reasonable stability for 30 days.
Conclusions: The developed CP NLCs DANs showed a controlled release profile, and the adsorption technique can be used to improve the stability of NLC dispersion. The DANs can be offered in patient-friendly dosage forms such as sachets, capsules, and compressed tablets.
Imaginarios, Barreras y Creencias que Limitan la Adopción de Hábitos y Estilos de vida Saludable en la Población Adulto Joven de la Zona Urbana de Zipaquirá
Authors: Aguilera Rojas Sandra Elizabeth , Torres Reyes Patricia , García Peña Angela Rocío , Ruiz Garcia Luz Amparo 
Published: November 2023

Objetivo: Conocer cuáles son los imaginarios, barreras y creencias que limitan la adopción de Hábitos y Estilos de Vida Saludable en la población joven estudiante del municipio de Zipaquirá. Métodos: Estudio descriptivo de corte transversal, conto con la participación de estudiantes matriculados en instituciones educativas del Municipio de Zipaquirá Cundinamarca, en una muestra n=186 (18-28 años). Se realizó un análisis bivariado para determinar la asociación de categorías o variables con Chi- cuadrado y establecer la adherencia según barreras y adopción de hábitos por grupo etario, sexo y zona de residencia. Resultados, De acuerdo con las dimensiones analizadas referentes a estilos de vida saludables el 66.7% no realiza actividad física por falta de tiempo y un 40% por escasa motivación; en salud mental el 31.7% considera falta información referente a este ámbito y el 40.9% considera la salud mental está relacionada con condiciones familiares; respecto a las condiciones de salud e higiene el 26.9% considera estas están relacionadas con condiciones económicas; al indagar por hábitos alimentarios y alimentación saludable el 25.3% refiere la adopción de estos está ligada a las condiciones económicas y finalmente en la dimensión sexualidad el 32.3% considera se requiere mayor información al respecto. Conclusiones, la investigación demostró que los imaginarios, barreras y creencias que limitan la adopción de Hábitos y Estilos de Vida Saludable en la población objeto no presentan diferencias por genero ni edad, se reconoce la importancia en el mantenimiento de la salud y prevención de la enfermedad.
Acute Care Interprofessional Event Improved Knowledge, Attitudes, and Practices of Athletic Training and Nurse Practitioner Students
Authors: Doud Victoria , Allesee Taylor , Dikanda Muteba , Mangum L. Colby , Gual Carlos J. 
Published: November 2023

Objective
In this study, we sought to assess the changes in the knowledge, attitudes, and practices (KAP) of athletic training program (ATP) and nurse practitioner (NP) graduate students before and after an acute care interprofessional education (IPE) workshop.

Design and Setting
This was a descriptive KAP survey to be taken by participants before and after the IPE event. This survey was administered using a QR code that participants scanned. The study occurred at the University of Central Florida College of Nursing before and after acute care skills were taught and practiced by each program’s students.

Patients or Other Participants
A total of 35 students from a professional master’s ATP and an adult gerontology acute care NP program were present at the workshop. Thirty-two students took the preworkshop survey, while 30 students completed the postworkshop survey.

Main Outcome Measure(s)
In this study, we aimed to measure the change in perceptions about the knowledge, skills, teaching, and IPE understanding of each respective program after the educational workshop. Surveys were distributed before the IPE workshop and then again after the workshop concluded. The survey responses were scored on a 5-point Likert scale. Scores for each section were averaged, and statistical analysis was done using repeated measures analyses of variance for total and subsection scores for both programs.

Results
A significant increase was found for each group in IPE understanding, knowledge, skills, and teaching scoring (P &lt; .05) with moderate to large effect sizes.

Conclusions
Participating in this acute care IPE workshop showed significant increases in perceptions of the KAP among ATP and NP students.
UMA ANÁLISE DA CIENTIFICIDADE DA TEORIA SOCIAL CRÍTICA DO GEÓGRAFO MARXISTA DAVID HARVEY
Authors: Ferreira da Silva Mariza , Lopes Diniz Filho Luis , Silvestre de Albuquerque Edu 
Published: November 2023

O texto apresenta os principais fundamentos teóricos do geógrafo crítico marxista David Harvey, que influenciou gerações de geógrafos pelo mundo desde a década de 1960. O objetivo é analisar a cientificidade da teoria social crítica, bem como fazer uma análise epistemológica das teorias econômicas elaboradas por esse geógrafo. As análises geográficas assentadas na filosofia da dialética histórica e materialista de David Harvey convergem para uma teoria crítica do capitalismo e da revolução social. Vale notar, que mesmo em suas obras consideradas próximas ao pensamento pós-modernista e à teoria da regulação, os pressupostos da determinação da infraestrutura econômica e da visão da luta de classes como motor da história, nunca foram abandonados. Em sua concepção, as contradições do capital devem ser explicadas porque são universais e perpassam as demais contradições sociais. De modo que é possível afirmar que em David Harvey, marxismo e pós-modernismo convergem enquanto campos analíticos da teoria social crítica e fazem parte do sistema crítico-filosófico da ciência racionalista moderna. Por essa razão, é possível questionar a cientificidade da geografia proposta por Harvey à luz do critério de falseabilidade e com base na análise do contexto de justificação tal como proposta por Karl Popper.

Palavras-chave: Teoria Social Crítica; Paradigmas Científicos; Filosofia da Ciência.
Ein polnischer Minorit als kaiserlicher Gesandtschaftspriester in Stockholm
Authors: Holzapfel Helmut 
Published: November 2023

Przedmiotem artykułu jest przedstawienie historii Kościoła katolickiego w Szwecji i wysiłków podejmowanych w celu zapewnienia duszpasterstwa katolikom w tym kraju. Autor zwrócił uwagę, że w XVIII wieku w Szwecji z powodu braku księży katolicy byli praktycznie pozbawieni sakramentów świętych i opieki duszpasterskiej. W tym czasie w Szwecji tylko przedstawiciele ambasad z krajów katolickich mogli korzystać z posługi kapelanów. Z wielkim trudem wspomniani kapelani starali się także sprawować sakramenty święte wśród zagranicznych katolików, którzy przebywali w Sztokholmie jako artyści, rzemieślnicy lub żołnierze. Próby nawracania rodowitych Szwedów na religię katolicką w każdym przypadku oznaczały śmierć lub wydalenie z kraju. W artykule opisano działalność Christopha Theodora Antivariego, austriackiego dyplomaty i wysłannika cesarskiego na dworze szwedzkim, który kontaktując się z różnymi zakonami podejmował próby zatrudnienia kapelana dla ambasady austriackiej w Sztokholmie. W tekście przypomniano szczególnie polskiego franciszkanina, który był jednym z kapelanów pracujących wśród katolików w Szwecji.
THE EFFECT OF PROBLEM BASED LEARNING MODEL THROUGH HOME VISITS AND LEARNING MOTIVATION ON Pipkin LEARNING OUTCOMES OF CLASS IV STUDENTS OF UPT SPF SDN 106828 SUMBERJO
Authors: Ade Candra Fadhlin Ade Candra , Setiawan Deny , Yus Anita 
Published: November 2023

This study aims to determine (1) the learning outcomes of students' PPKn taught by the Problem Based Learning model through home visits are higher than the PPKn learning outcomes of students taught by the Problem Based Learning model through Google Classroom; (2) PPKn learning outcomes of students who have high learning motivation are higher than students who have low learning motivation; (3) The interaction between the Problem Based Learning model through home visits and learning motivation on the learning outcomes of fourth grade PPKn at UPT SPF SDN 106828 Sumberjo. This research is in the form of a quasi-experimental design with a 2 x 2 factorial design. The population of this research is all fourth-grade students of UPT SPF SDN 106828, which are 2 classes with a total of 54 students. The sample selection was taken by using a total sampling technique, namely from the two classes as a whole set as a sample. Thus, the sample was determined, namely class IVA as group A and class IVB as group B. Class determination for the application of the learning model was determined by group A consisting of 27 students for classes taught using the Problem Based Learning model through home visits, and group B consisting of 27 students for classes taught using the Problem Based Learning model through google classroom. The research instrument used a multiple-choice learning outcome test with 25 questions and a student learning motivation instrument in the form of a questionnaire consisting of 40 items that were declared valid and reliable. Data analysis using two-way Anova. The results showed that (1) the learning outcomes of PPKn Education students who were taught using the Problem Based Learning model through home visits were higher than the Problem Based Learning model through the Google Classroom; (2) PPKn learning outcomes of students who have high learning motivation are higher than students who have low learning motivation; (3) There is an interaction between the learning model and learning motivation in influencing student PPKn learning outcomes.
THE INFLUENCE OF GUIDED INQUIRY LEARNING MODELS ON SOCIAL SKILLS AND LEARNING OUTCOMES OF PPKN CLASS V STUDENTS SD NEGERI 091400 DOLOK SARIBU
Authors: Purba Novridah Reanti , Setiawan Deny , Saragi Daulat 
Published: November 2023

This research is motivated by PPKn learning activities still using conventional learning models so that learning is less than optimal. This study aims to determine: (1) how much influence the guided inquiry model has on students' social skills, (2) how much influence the guided inquiry model has on the learning outcomes of ppkn students in grade V of SD Negeri 091400 Dolok Saribu, (3) whether there is an interaction between social skills and ppkn learning outcomes of grade V students of SD Negeri 091400 Dolok Saribu. This research is a quasi-experimental research. The population in this study was all grade IV students of SD Negeri 091400 Dolok Saribu for the 2020/2021 School Year consisting of two classes. The research sample used was all grade IV students of SD Negeri 0901400 using the total sampling sample technique. The instruments used are social skills questionnaires and ppkn class IV learning outcomes tests. The data obtained were then analyzed using ANACOVA and ANAVA in the spss 2 2 program. The results showed that: 1) the magnitude of the influence of the guided inquiry model on the social skills of grade IV students was 0.9 31 or 9 3.1%, 2) the large influence of the guided inquiry model on the learning outcomes of ppkn grade IV students was 0.967 or 9.67%, 3) there was an interaction between the inquiry learning model is guided by social skills and learning outcomes of ppkn grade IV students with a calculated F score of 3,906 so that Ha is accepted and H0 is rejected.
Analisis Miskonsepsi Siswa XI MIA 1 SMA Negeri 1 Pangkajene pada Materi Pokok Hidrokarbon
Authors: Reny Reny , Astuti Sry , Rahayu Ayu 
Published: November 2023

This descriptive research aims to analyze the student’s misconceptions on hydrocarbon subject that have been learned by STAD Type of Cooperative Learning Model. The subjects in research are 31 students of SMA Negeri 1 Pangkajene class XI MIA 1. The data was collected by 7 items essay test and intensified by interviews. The data was analyzed by descriptive statistic method to obtain percentage of the misconseption. The result of this research shows that student’s misconception is low category, 17% in determining C atom of primary, secondary, tertiary, and quaternary. In naming of alkanes, alkenes, and alkyne’s structure, is low category, average 24,5%. In understanding addition and subtitusi reaction of hydrocarbon is low category, 22,4%. And low category, average 21,3% on misconception of hydrocarbon in generallydisciplining teachers and motivating them to comply with the foundation's policies is a problem that must be immediately found a solution. This research uses a qualitative approach, data sources obtained through interviews through zoom applications, documentation, and observation. This article found that PAUD al Ashriyyah Principal Nurul Iman in improving teacher discipline used autocratic style to be the dominant style, not seen other styles played by principals in the leadership model. The principal in improving the work discipline of his teachers does not always run smoothly, the obstacles and obstacles
Impact of technological practices on the photosynthetic productivity of spring barley in Northern Forest-Steppe conditions
Authors: Porod’ko M. A. 
Published: November 2023

Aim. To determine the features of the formation of the photosynthetic apparatus in spring barley plants depending on the influence of individual elements of cultivation technology and to identify the most effective combinations for maximizing the genetic potential of the crop under the conditions of the northern part of the Right-Bank Forest-Steppe of Ukraine. Methods. During the research, a field study method, visual observation, weighing, the «cutting» method, calculations, and statistical analysis were applied. Results. The research conducted during 2018–2020 has shown that the fertilization system, the use of growth stimulants, and the preceding crop significantly influence the photosynthetic activity of spring barley plants at different stages of organogenesis. The leaf surface index values increased and reached their maximum at the VII and IX stages of organogenesis, after which they gradually decreased. The maximum leaf surface area of 5.03 to 5.24 m2/m2 was achieved in crops with the application of N60P80K80+N60(IV) in the presence of the preceding crop’s by-product. The photosynthetic potential of crops during the period from the II to XI stages of organogenesis was at the level of 1.02–2.42 million m2/ha·day when grown after soybeans and 0.92–2.39 million m2/ha·day when grown after corn for grain. The period from the IV to VIІІ stages of plant organogenesis was characterized by the most active accumulation of dry matter and the most significant influence of all studied agronomic practices on the formation of this indicator. Conclusions. Optimal indicators of photosynthetic activity of spring barley crops (leaf area index of 4.65 m²/m² at the VIII stage of organogenesis, net photosynthesis productivity of 6.71 g/m² per day, dry matter accumulation of 9.51 t/ha at the XI stage of organogenesis) are ensured by the cultivation technology that involves the application of mineral fertilizers at a rate of N45P90K90+N45(IV) against the background of the predecessor’s (corn for grain) byproduct and the use of growth stimulants for pre-sowing seed treatment and foliar application at the IV stage of organogenesis. Such parameters of plant photosynthetic apparatus operation contribute to obtaining a barley grain yield at the level of 4.88–5.27 t/ha.
Efektivitas Pembelajaran Dengan Model Seven Jumps Berbantuan Wag Di Masa Pandemi Covid-19
Authors: Hartutik Hartutik  , Prabandari C.D  , Astuti Andarweni  , Epilia F  
Published: November 2023

Seeing the root of the problem of student independence during the Covid-19 pandemic, implementing the effectiveness of learning with the Seven Jumps model assisted by the whatsapp group during the Covid-19 Pandemic is the aim of this research. This type of research approach is a qualitative and quantitative experiment carried out online with the Seven Jumps learning model assisted by WhatsApp groups. Data was collected by questionnaires, observation sheets and tests. Valid device tests come from expert perceptions, test the effectiveness of learning with statistical tests of the effect of regression and comparative t tests.
The results showed that the root problems and constraints for student independence in utilizing information technology to achieve the expected competencies were: low self-motivation to learn, self-assessment ability, self-discipline, self-control, responsibility, pattern-learning ability, self-reliance in designing appropriate learning objectives, design implementation strategies, monitoring the progress of learning outcomes, coordination of learning methods, and the need for guidance in finding learning resources, implementing independent learning with the Seven Jumps model assisted by the whatsapp group is effective. This is indicated by: a) there is a positive influence of independent learning on problem solving ability of 60.8%, b) The gain test to measure the effectiveness of the pretest and posttest is 0.52 in the medium category and the effectiveness is sufficient. The Seven Jumps method can be implemented boldly during the Covid-19 Pandemic.
ANALYSIS THE ABILITY UNDERSTANDING THE CONCEPT STUDENTS IN CLASS VIII OF SMP ORAHILI FONDRAKO QUADRATIC
Authors: Ronal Raigen Giawa  
Published: November 2023

One of the problem which obtained by the researcher was the lack of ability in understanding mathematical concepts at the VIII grade students at orahili fondako on quadratic equation material. This research is aimed to describe the ability of mathematical concept understanding of students at the VIII grade at orahili fondako village on quadratic equation material and to know what are the students' difficulty at the VIII grade of orahili fondako village in finishing the concept comprehending ability especially on quadratic equation material. This research used qualitative descriptive research. The subject of the research was students at VIII grade in orahili fondako village which consists of 15 persons. The technique of collecting data was done by observation and test to the subject of the research. Data was analyzed by the steps as follow, data reduction, data display and verifing conclusion. As the result of the research shows that the mathematical concepts understanding at the VIII grade on quadratic equation material takes place under category by the percentage was 33%. The difficulties which got by the students in finising a test of mathematical concept understanding ability on quadratic equation material which students was lack to comprehend the test of the test given where, the students did not know what is the meaning and the purpose was asked of the case, then the students also still lack to elaborate that concept in a test, so the students were not able to answer the case of the test given and the students still lacked in understanding the steps in describing quadratic equation graphic. Furthermore, students still not able to apply the concept of quadratic equation in the case of problem solving. The researcher suggesting that the teacher and parent be collaborated on online learning proces which is applying nowdays so that the students' mathematical concept understanding be improved.
Bioética Recobrada. Un regreso a los límites
Authors: Pichardo Hortencia Cuellar Luz Ma 
Published: November 2023

En el 2020, celebraremos el cincuentenario de la aparición formal de la bioética en el escenario científico global. El afortunado neologismo usado por Potter en 1970 para vincular las ciencias experimentales con las ciencias humanísticas, creando un enfoque interdisciplinar indispensabel -esencia de la bioética- , el cual pretende recuperar el liderazgo de la filosofía -particularmente de la ética- a fin de orientar a propiadamente los desarrollos de las ciencias prácticas en boga, como la biología, la ecología, la química, la cibernética, las nuevas biotecnologías, siempre con respeto de la dignidad del ser humano y su entorno. Es necesario estar alerta a ciertas tendencias actuales guiadas principalmente por intereses económicos y posverdad, corrientes transhumanistas que parecieran dar un nuevo giro copernicano en la reflexión científico-filosófica, en donde la esencia del ser humano pareciera esfumarse y quedar al libre arbitrio de las ciencias cibernéticas. ¿Qué hacer entonces? El reto que se vislumbra en el horizonte es volver a descubrir una racionalidad que la sustente, o como Potter decía en 1970: "El conocimiento de cómo utilizar el conocimiento" ¿Qué tan cerca está esta nueva ciencia de alcanzar las metas que su fundador Van Rensselaer Potter propuso para unir las ciencias experimentales con las ciencias humanísticas? ¿La biología con la Filosofía, y a su vez destacar la urdimbre jurídica que de manera natural brota ante problemáticas y retos tan relevantes en el ámbito clínico, como sonlos que aborda y atiende la boética como ciencia? De ahí el interés en aportar un conjunto de escritos científicos acerca de sus fundamentos y principales aplicaciones, tanto para el personal de salud, alumnos de pregrado y posgrado, docentes, como a quienes pertenecen a comités hospitalarios: abogados, filósofos, representantes religiosos, así como profesionales de otros ámbitos, incluidas la investigación de la práctica clínica, que les permita tomar las decisiones correctas, dentro del marco del derecho sanitario vigente de nuestro país y conforme a los tratados internacinales de los que México es parte. El libro tiene como objetivo presentar a los estudiantes, docentes, investigadores y profesionales de distintas carreras, interesados en este ámbito, los fundamentos antropológicos y humanísticos de la novedosa y polémica ciencia de la bioética, sus campos de aplicación, los dilemas que suelen presentarse, asi como algunas propuestas de solución de casos clínicos concretos por un grupo interdisciplinar de académicos deprestigiadas instituciones educativas de nuestro país.