bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of abdominal hot pack application on gastrointestinal motility recovery after comprehensive gynecologic staging surgery
Authors: Güngördük Kemal , Selimoğlu Berfin , Gülseren Varol , Yasar Eylem , Comba Cihan , Özdemir İsa Aykut 
Published: October 2023

AbstractObjectiveTo evaluate whether abdominal hot water pack application improves gastrointestinal motility following gynecological oncology surgery.MethodsThe study was registered at ClinicalTrials.gov (NCT04833699). (https://clinicaltrials.gov/ct2/show/NCT04833699?cond=NCT04833699&draw=2&rank=1). In this randomized controlled trial, participants were randomly assigned (1:1) to the hot water pack group (standardized enhanced recovery protocols plus rubber water bag with a fluffy cover filled with boiled tap water [80°C] and placed on the abdomen at 3, 6, 9, and 12 h postoperatively for 30 min each time) or the control group (standardized enhanced recovery protocols). A subumbilical or supraumbilical vertical midline incision was made to perform staging surgery procedures, including hysterectomy, salpingo‐oophorectomy with retroperitoneal lymphadenectomy. The primary outcome was the time to first passage of flatus from the end of the staging procedure.ResultsIn total, 121 women were randomized to the control (n = 62) or hot water pack (n = 59) group. The use of an abdominal hot water pack significantly reduced the mean time to passing first flatus (25.2 ± 3.6 vs. 30.6 ± 3.9 h; hazard ratio [HR] = 4.4; 95% confidence interval [CI]: 2.8–7.1; P < 0.0001), mean time to first bowel movements (28.4 ± 4.0 vs. 34.4 ± 4.5 h; HR = 4.9; 95% CI: 3.0–7.9; P < 0.0001), mean time to first defecation (33.4 ± 4.9 vs. 41.0 ± 7.6 h; HR = 4.3; 95% CI: 2.1–6.8; P < 0.0001), and mean time to tolerating solid diet (2.1 ± 0.6 vs. 2.8 ± 1.0 days; HR = 4.4; 95% CI: 2.2–8.7; P < 0.0001) compared to the control group. The postoperative ileus incidence was significantly lower in the hot water pack group (3.4%) than the control group (16.1%) (P = 0.01).ConclusionAbdominal hot water pack application improved gastrointestinal function recovery in women following surgical staging procedures for gynecological malignancy.
Fostering humanistic counseling via utilizing the Search Institute's Asset Checklist: An outcome study
Authors: Coll Kenneth M. , Stewart Roger A. , Sawyer Stephanie , Woodliff Tricia , Fear Clark , Scholl Stacey , Hauser Nicole 
Published: October 2023

AbstractThis study combined asset (i.e., strength) assessment, measured by the Search Institute's Asset Checklist, and humanistic counseling approaches to measure effects on self‐reported assets in two similar vulnerable adolescent populations in therapeutic residential treatment centers located in the rural Rocky Mountain West. Results indicated that seven of eight asset categories increased from baseline to follow‐up assessment, with four of those categories having statistically significant increases. Total Asset scores also indicated substantial overall asset building during treatment. Suggestions are included, especially for one concerning area, Constructive Use of Time.
A Temperature and pH Dual‐Sensitive Multifunctional Polyurethane with Bacteria‐Triggered Antibacterial Activity
Authors: Gao Qinwei , Chen Zhaobin , Yang Xiaoniu 
Published: October 2023

AbstractAn effective and practical antibacterial strategy is to design multifunctional and stimuli‐responsive materials that exhibit antibacterial activity in response to bacterial triggers. In this study, because the metabolism of Staphylococcus aureus (S. aureus) can acidify the surrounding environment and pH level can affect the lower critical solution temperature of temperature/pH dual‐sensitive polymers, a monomer containing a temperature‐sensitive N‐isopropyl amide derivative and pH‐sensitive tertiary amine groups is first synthesized. Then, the monomer is copolymerized with a polyurethane chain, and partial tertiary amine groups are quaternized to obtain bactericidal activity. The modified polyurethane exhibits temperature/pH sensitivity, antibacterial adhesion activity, bactericidal activity, and good cytocompatibility. An in situ investigation of bacterial behavior and pH changes in the bacterial suspension during the process confirms that the temperature/pH dual‐sensitive polyurethane successfully achieves antibacterial activity though the metabolic activity of S. aureus without external intervention. This design concept provides a new perspective for antibacterial material design.
Effectiveness of visual biofeedback–guided respiratory‐correlated 4D‐MRI for radiotherapy guidance on the MR‐linac
Authors: Keijnemans Katrinus , Borman Pim T. S. , Raaymakers Bas W. , Fast Martin F. 
Published: October 2023

AbstractPurposeRespiratory‐correlated 4D‐MRI may provide motion characteristics for radiotherapy but is susceptible to irregular breathing. This study investigated the effectiveness of visual biofeedback (VBF) guidance for breathing regularization during 4D‐MRI acquisitions on an MR‐linac.MethodsA simultaneous multislice‐accelerated 4D‐MRI sequence was interleaved with a one‐dimensional respiratory navigator (1D‐RNAV) in 10 healthy volunteers on a 1.5T Unity MR‐linac (Elekta AB, Stockholm, Sweden). Volunteer‐specific breathing amplitudes and periods were derived from the 1D‐RNAV signal obtained during unguided 4D‐MRI acquisitions. These were used for the guidance waveform, while the 1D‐RNAV positions were overlayed as VBF. VBF effectiveness was quantified by calculating the change in coefficient of variation () for the breathing amplitude and period, the position SD of end‐exhale, end‐inhale and midposition locations, and the agreement between the 1D‐RNAV signals and guidance waveforms. The 4D‐MRI quality was assessed by quantifying amounts of missing data.ResultsVBF had an average latency of 520 ± 2 ms. VBF reduced median breathing variations by 18% to 35% (amplitude) and 29% to 57% (period). Median position SD reductions ranged from −3% to 35% (end‐exhale), 29% to 38% (end‐inhale), and 25% to 37% (midposition). Average differences between guidance waveforms and 1D‐RNAV signals were 0.0 s (period) and +1.7 mm (amplitude). VBF also decreased the median amount of missing data by 11% and 29%.ConclusionA VBF system was successfully implemented, and all volunteers were able to adapt to the guidance waveform. VBF during 4D‐MRI acquisitions drastically reduced breathing variability but had limited effect on missing data in respiratory‐correlated 4D‐MRI.
Generalized Ng–Kundu–Chan model of adaptive progressive Type‐II censoring and related inference
Authors: Schmiedt Anja Bettina , Cramer Erhard 
Published: October 2023

AbstractThe model of adaptive progressive Type‐II censoring introduced by Ng et al. (2009) (referred to as Ng–Kundu–Chan model) is extended to allow switching from a given initial censoring plan to any arbitrary given plan of the same length. In this generalized model, the joint distribution of the failure times and the corresponding likelihood function is derived. It is illustrated that the computation of maximum likelihood and Bayesian estimates are along the same lines as for standard progressive Type‐II censoring. However, the distributional properties of the estimators will usually be different since the censoring plan actually applied in the (generalized) Ng–Kundu–Chan model is random. As already mentioned in Cramer and Iliopoulos (2010), we directly show that the normalized spacings are independent and identically exponentially distributed. However, it turns out that the spacings themselves are generally dependent with mixtures of exponential distributions as marginals. These results are used to study linear estimators. Finally, we propose an algorithm for generating random numbers in the generalized Ng–Kundu–Chan model and present some simulation results. The results obtained also provide new findings in the original Ng–Kundu–Chan model; the corresponding implications are highlighted.
Soil carbon mineralization, enzyme activities, and crop residue decomposition under varying soil moisture regimes
Authors: Chatterjee Amitava , Taylor Jason M. , Strauss Alana , Locke Martin A. 
Published: October 2023

AbstractIn the Lower Mississippi River Basin, farmlands are flooded in late fall and winter by impeding drainage to provide a habitat for migratory birds stopover. A laboratory incubation study was conducted to study the influence of temporary wetting of these soils on carbon (C) and nitrogen (N) mineralization from residue decomposition. Surface soils (0–15 cm) were collected from fields with clay and silty clay loam soils. Both soils were incubated with five crop residues—corn (Zea mays), soybean (Glycine max), cotton (Gossypium hirsutum), sorghum (Sorghum bicolor), and sweet potato (Ipomea batatus)—at 50% and 100% water holding capacity (WHC). Soil carbon dioxide (CO2) efflux was measured during 74 days of incubation. Soil moisture had the largest effect on soil CO2efflux and most of the enzyme activities followed by residue and soil type. Cumulative soil CO2efflux was reduced by 46% at 100% WHC compared to 50% WHC. Clay soil had higher cumulative CO2efflux, aryl sulfatase, aryl phosphatase, and β‐N‐acetyl glucose aminidase activities than silty clay loam soil. Residue type had the largest effect on post‐incubation soil inorganic‐N, remaining biomass, and residue C and residue N. Sweet potato residue had the lowest remaining biomass, significantly lower than cotton, corn, and sorghum, but statistically similar to soybean. After incubation, residue N concentration had a positive association with cumulative CO2efflux and a negative association with remaining residue biomass percentage. Winter flooding might limit the loss of soil C as CO2depending on the crops grown and soil type.
Bone‐Targeted Nanoparticle Drug Delivery System‐Mediated Macrophage Modulation for Enhanced Fracture Healing
Authors: Xiao Baixue , Liu Yuxuan , Chandrasiri Indika , Adjei‐Sowah Emmanuela , Mereness Jared , Yan Ming , Benoit Danielle S. W. 
Published: October 2023

AbstractDespite decades of progress, developing minimally invasive bone‐specific drug delivery systems (DDS) to improve fracture healing remains a significant clinical challenge. To address this critical therapeutic need, nanoparticle (NP) DDS comprised of poly(styrene‐alt‐maleic anhydride)‐b‐poly(styrene) (PSMA‐b‐PS) functionalized with a peptide that targets tartrate‐resistant acid phosphatase (TRAP) and achieves preferential fracture accumulation has been developed. The delivery of AR28, a glycogen synthase kinase‐3 beta (GSK3β) inhibitor, via the TRAP binding peptide‐NP (TBP‐NP) expedites fracture healing. Interestingly, however, NPs are predominantly taken up by fracture‐associated macrophages rather than cells typically associated with fracture healing. Therefore, the underlying mechanism of healing via TBP‐NP is comprehensively investigated herein. TBP‐NPAR28 promotes M2 macrophage polarization and enhances osteogenesis in preosteoblast‐macrophage co‐cultures in vitro. Longitudinal analysis of TBP‐NPAR28‐mediated fracture healing reveals distinct spatial distributions of M2 macrophages, an increased M2/M1 ratio, and upregulation of anti‐inflammatory and downregulated pro‐inflammatory genes compared to controls. This work demonstrates the underlying therapeutic mechanism of bone‐targeted NP DDS, which leverages macrophages as druggable targets and modulates M2 macrophage polarization to enhance fracture healing, highlighting the therapeutic benefit of this approach for fractures and bone‐associated diseases.
Microphysiological Constructs and Systems: Biofabrication Tactics, Biomimetic Evaluation Approaches, and Biomedical Applications
Authors: Zhang Shuyu , Xu Guoshi , Wu Juan , Liu Xiao , Fan Yong , Chen Jun , Wallace Gordon , Gu Qi 
Published: October 2023

AbstractIn recent decades, microphysiological constructs and systems (MPCs and MPSs) have undergone significant development, ranging from self‐organized organoids to high‐throughput organ‐on‐a‐chip platforms. Advances in biomaterials, bioinks, 3D bioprinting, micro/nanofabrication, and sensor technologies have contributed to diverse and innovative biofabrication tactics. MPCs and MPSs, particularly tissue chips relevant to absorption, distribution, metabolism, excretion, and toxicity, have demonstrated potential as precise, efficient, and economical alternatives to animal models for drug discovery and personalized medicine. However, current approaches mainly focus on the in vitro recapitulation of the human anatomical structure and physiological‐biochemical indices at a single or a few simple levels. This review highlights the recent remarkable progress in MPC and MPS models and their applications. The challenges that must be addressed to assess the reliability, quantify the techniques, and utilize the fidelity of the models are also discussed.
A Long‐Life and Excellent Rate‐Capability Aqueous Zn‐Benzoquinone Battery Enabled by Iodine‐Catalyzed Cathode
Authors: Song Chunlai , Wang Qiang , Wen Ruihang , Tang Qiben , Luo Zhiqiang , Yuan Zhihao 
Published: October 2023

AbstractBenzoquinone (BQ) is considered to be a desirable cathode material for aqueous zinc‐based batteries. The major limitations of BQ electrode are the severe sublimation and poor electrical conductivity, which results in serious mass loss during electrode preparation and inferior rate performance. In this study, iodine (I2) species are utilized as an efficient catalyst for the highly reversible conversion of BQ/BQ2− couple in the Zn‐BQ battery system, wherein N‐doped porous carbon is employed as a host material for anchoring the BQ molecule. In the combination electrode (denoted as BQ‐I@NPC) with 1wt% I2 additive where I2 can serve as a carrier to accelerates the Zn2+ transmission, and reduce the voltage hysteresis of the electrode. As a result, the BQ‐I@NPC cathode delivers a high specific capacity of ≈482 mAh g−1 at 0.25 A g−1, realizing a high energy density of 545 Wh kg−1 (based on BQ), which is the highest values among reported organic cathode materials for aqueous Zn‐based batteries. Also, a high BQ loading (8 mg cm−2) can be attained, and achieving a superior cycling stability with a capacity retention of ≈80% after 20,000 times at 10 C. The work proposes an effective approach toward high performance organic electrode materials.
CDTC: Automatically establishing the trace links between class diagrams in design phase and source code
Authors: Chen Fangwei , Zhang Li , Lian Xiaoli 
Published: October 2023

AbstractContextThe UML class diagram is commonly used to model functional structures and software code structures in both the preliminary and detailed design stages. And the abstraction level of UML class diagrams is usually higher than that of source code. Usually, there is a lack of trace links between these class diagrams and the source code, which may cause difficulties in understanding the source code, and affect the software evolution and maintenance.ObjectiveThe main goal of this article is to establish the trace links between highly abstracted UML class diagrams in the design phase and source code, and eventually help practitioners better understand source code.MethodWe propose an approach for the automated trace link establishment between UML class diagrams in the design phase and source code. To address the problem of abstraction level gap between them, we extend the UML class diagram by mining the synonymous phrases of class names and deducing the latent missing relationships between classes from multiple design documents. Then we build the trace links with a two‐phase approach including initial construction with fuzzy matching and further optimization by class relationship inference.ResultsExperiments on five open‐source projects show that the recalls of our approach are over 94%, and the F2‐scores are over 88%, with the gains of 30% to 60% than the four baselines.ConclusionOur work can be a reference for establishing the initial trace links between highly‐abstracted UML class diagrams and source code. Towards the higher abstraction of design diagrams, we extend UML class diagrams with the statistical analysis on multiple design documents. To guarantee the quality of trace links, we design a two‐phase approach by obtaining the “full but not good enough” trace links and filtering the “probably wrong” links. Experiments show that the main techniques of our approach behave as important role for tracing between high‐level class diagrams and source code.
Challenges and Reflections for Developing Leadership in Educational Contexts
Authors: Ahtiainen Raisa , Hanhimäki Eija , Leinonen Jaana , Risku Mika , Smeds-Nylund Ann-Sofie 
Published: October 2023

AbstractThis volume was inspired by the observation that over the past 20 years, the educational system and public administration in general have changed enormously due to ideological, political and structural transformation. In practice, the mode of operation in educational organisations is characterised by a complex interplay between political and administrative objectives, negotiations and promotion of various perspectives, cultural features, professional sights and aims to adapt to external and internal pressures and influences. This has affected educational leadership that should also be seen from a complex perspective that includes relationships and active social interaction in various networks. However, there have been very few publications of the specifics of leadership in educational contexts with a wide-ranging perspective for the radically evolving operational environments and written by researchers in educational leadership and governance. Therefore, this volume has presented a joint effort for positioning, conceptualising and describing the nature and future of Finnish educational leadership for both the international and Finnish readers.
Exploring Social Representations of Nature-Based Tourism, Development Conflict, and Sustainable Development Futures in Chilean Patagonia
Authors: Inostroza Villanueva Gabriel , Bourlon Fabien , Gale-Detrich Trace , Blair Heidi 
Published: October 2023

AbstractThis chapter explored howModernization,Transformation, andControlSustainable Development (SD) imaginaries and trajectories interacted, nuanced, and mediated the approaches of neoliberaldevelopment initiatives and the conflicts which surrounded them. A collective case study approach was employed to better understand actors, their strategies, and perceptions about three large-scale development proposals, the Patagonia National Parks network, the HidroAysén hydroelectric project, and the Río Cuervo hydroelectric project. We identified six themes that characterized participants’ preferences related to processes: a desire for greater proactiveness aroundtransparency, abindingparticipationprocess of governance,bottom-updecision making,re-empowermentof local groups,decentralization, andimproved oversightpractices. Further, directed content analysis revealed numerous manifestations of the three SD futures trajectories and several examples of interactions and overlap between the SD imaginaries. Seemingly, some development actors navigated between SD imaginaries and tactics to maneuver between local and national actors, agendas, and decision-making processes. We have termed these tactics asSD agility, which are initially defined as: “the strategic ability to maneuver between SD imaginaries and trajectories to achieve strategic SD outcomes.” SD agility tactics merit additional study as we believe they may represent an important capacity for SD futures trajectories.
Territorializing Capital: Moreno’s Gift and the Political Economy of Nature in Argentine Patagonia
Authors: Mendoza Marcos 
Published: October 2023

AbstractThis chapter examines the political economy of nature and the legacy of Francisco Moreno, scientist and explorer, within ArgentinePatagonia. Moreno is institutionally recognized for a land donation he made to the federalgovernment in 1903, which is celebrated for inaugurating the national park conservation movement. This Moreno-centric official history, however, has rendered invisible state violence and Indigenous dispossession as preconditions of national conservation. Moving beyond this official history of conservation, the discussion highlights two histories of capitalist territorialization. The first focuses on the clearing-out strategy pursued by the Argentine government to open Patagonia for colonization and agrarian capitalism. The second attends to the re-territorialization of space through the creation of national parks and the promotion of leisure capitalism. Using the concept of “the gift” to assess Moreno’s legacy, this chapter shows that the “spirit of the gift”—heralded by the Argentine federal government—is chained to these two projects of capitalist territorialization. These territorialization histories challenge the halcyon representation of Moreno’s gift promoted by the state. Drawing upon scholarship in politicalecology, this study is a contribution to an emerging critical assessment of “the gift” within Patagonian conservation.
Entanglement of harmonic systems in squeezed states
Authors: Katsinis D. , Pastras G. , Tetradis N. 
Published: October 2023

Abstract
The entanglement entropy of a free scalar field in its ground state is dominated by an area law term. It is noteworthy, however, that the study of entanglement in scalar field theory has not advanced far beyond the ground state. In this paper, we extend the study of entanglement of harmonic systems, which include free scalar field theory as a continuum limit, to the case of the most general Gaussian states, namely the squeezed states. We find the eigenstates and the spectrum of the reduced density matrix and we calculate the entanglement entropy. We show that our method is equivalent to the correlation matrix method. Finally, we apply our method to free scalar field theory in 1+1 dimensions and show that, for very squeezed states, the entanglement entropy is dominated by a volume term, unlike the ground-state case. Even though the state of the system is time-dependent in a non-trivial manner, this volume term is time-independent. We expect this behaviour to hold in higher dimensions as well, as it emerges in a large-squeezing expansion of the entanglement entropy for a general harmonic system.
The impact of usage on the performance of lubricating emulsions in micro-forming
Authors: Arinbjarnar Úlfar , Rahemipoor Sahand , Christiansen Rune J. , Bissacco Giuliano , Nielsen Chris V. 
Published: October 2023

AbstractLubricants are known to change over time, both in terms of aging of the oil and additives, and additive depletion through use. Samples were extracted at intervals from an industrial micro-deep drawing process line to evaluate how the lubricant changes over time. Four-ball testing showed that the tribological performance degraded quickly but stabilised after one million strokes. Measuring of the pH-level and correlation with the oil concentration showed that the emulsion initially becomes more acidic but stabilises after one million strokes, despite changes in oil concentration. Elemental analysis using water inductively coupled plasma (ICP) analysis standard showed that particles in the lubricant could be related to an increasing formation of wear debris. Fourier-transform infrared (FT-IR) analysis was used to evaluate changes in chemical composition of the base oil. Lubricant properties were found to degrade in samples obtained from the onset of the production, while they stabilised for samples that had been in use for a period of more than 1 week. The performance of the used lubricant is therefore different from that of the fresh lubricant, with four-ball wear scars increasing by approximately 30%. These results show that when tribological tests are tailored to industrial tribo-systems, the lubricant that is used in the test should be the steady state lubricant found in the real system rather than fresh lubricant.