bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Iowa Health Data Resource (IHDR): an innovative framework for transforming the clinical health data ecosystem
Authors: Davis Heath A , Santillan Donna A , Ortman Chris E , Hoberg Asher A , Hetrick Joseph P , McBrearty Charles W , Zeng Erliang , Vaughan Sarrazin Mary S , Dunn Lopez Karen , Chapman Cole G , Carnahan Ryan M , Michaelson Jacob J , Knosp Boyd M 
Published: December 2023

Abstract

Importance
This manuscript will be of interest to most Clinical and Translational Science Awards (CTSA) as they retool for the increasing emphasis on translational science from translational research. This effort is an extension of the EDW4R work that most CTSAs have done to deploy infrastructure and tools for researchers to access clinical data.

Objectives
The Iowa Health Data Resource (IHDR) is a strategic investment made by the University of Iowa to improve access to real-world health data. The goals of IHDR are to improve the speed of translational health research, to boost interdisciplinary collaboration, and to improve literacy about health data. The first objective toward this larger goal was to address gaps in data access, data literacy, lack of computational environments for processing Personal Health Information (PHI) and the lack of processes and expertise for creating transformative datasets.

Methods
A three-pronged approach was taken to address the objective. The approach involves integration of an intercollegiate team of non-informatics faculty and staff, a data enclave for secure patient data analyses, and novel comprehensive datasets.

Results
To date, all five of the health science colleges (dentistry, medicine, nursing, pharmacy, and public health) have had at least one staff and one faculty member complete the two-month experiential learning curriculum. Over the first two years of this project, nine cohorts totaling 36 data liaisons have been trained, including 18 faculty and 18 staff. IHDR data enclave eliminated the need to duplicate computational infrastructure inside the hospital firewall which reduced infrastructure, hardware and human resource costs while leveraging the existing expertise embedded in the university research computing team. The creation of a process to develop and implement transformative datasets has resulted in the creation of seven domain specific datasets to date.

Conclusion
The combination of people, process, and technology facilitates collaboration and interdisciplinary research in a secure environment using curated data sets. While other organizations have implemented individual components to address EDW4R operational demands, the IHDR combines multiple resources into a novel, comprehensive ecosystem IHDR enables scientists to use analysis tools with electronic patient data to accelerate time to science.
Transmission of Xanthomonas albilineans by the spittlebug, Mahanarva fimbriolata (Hemiptera: Cercopidae), in Brazil: first report of an insect vector for the causal agent of sugarcane leaf scald
Authors: Bini Andressa Peres , Serra Marina Carnaz Duarte , Pastore Izadora Farina , Brondi Carolina Veluci , Camargo Luis Eduardo Aranha , Monteiro-Vitorello Claudia Barros , van Sluys Marie-Anne , Rossi Guilherme Duarte , Creste Silvana 
Published: December 2023

Abstract
Leaf scald is a destructive sugarcane disease caused by the bacterium Xanthomonas albilineans (Ashby) Dowson. This pathogen presents the gene cluster SPI-1 T3SS, a conserved feature in pathogens vectored by animals. In this study, the competence of Mahanarva fimbriolata (Stål), a spittlebug commonly found in sugarcane fields in Brazil, was evaluated for the transmission of X. albilineans. Artificial probing assays were conducted to investigate the ability of M. fimbriolata adults to acquire X. albilineans from artificial diets containing the pathogen with subsequent inoculation of X. albilineans into pathogen-free diets. Plant probing assays with M. fimbriolata adults were conducted to evaluate the acquisition of X. albilineans from diseased source plants and subsequent inoculation of healthy recipient sugarcane plants. The presence of X. albilineans DNA in saliva/diet mixtures of the artificial probing assays and both insects and plants of the plant probing assays were checked using TaqMan assays. The artificial probing assays showed that M. fimbriolata adults were able to acquire and inoculate X. albilineans in diets. Plant probing assays confirmed the competence of M. fimbriolata to transmit X. albilineans to sugarcane. Over the entire experiment, 42% of the insects had acquired the pathogen and successful inoculation of the pathogen occurred in 18% of the recipient-susceptible sugarcane plants at 72 or 96 h of inoculation access period. Assays evidenced the vector competence of M. fimbriolata for transmission of X. albilineans, opening new pathways for investigating the biology and the economic impacts of the interaction between X. albilineans and M. fimbriolata.
In situ TEM studies on hydrogen-related issues: hydrogen storage, hydrogen embrittlement, fuel cells and electrolysis
Authors: Matsuda Junko 
Published: December 2023

Abstract
Hydrogen is attracting attention as an energy carrier for realizing a low-carbon society, because it can directly convert the energy obtained from chemical reactions into electrical energy without carbon dioxide emissions. This paper presents in situ transmission electron microscopy (TEM) observations related to hydrogen storage in metal and metal hydrides, hydrogen embrittlement of metallic materials used for storing and transporting hydrogen in containers and pipes, and fuel cells and water electrolysis using metal catalysts and oxides as electrode materials. All of these processes are important for practical applications of hydrogen. Numerous in situ TEM studies have revealed the microscopic structural changes when hydrogen reacts with the materials, when hydrogen is solidly dissolved in the materials and during the operation of the material. This review is expected to facilitate further development of TEM operando observations of hydrogen-related materials.
Boiled watchdogs? The declining professional autonomy of precarious millennial generation journalists
Authors: Čehovin Zajc Jožica , Lukan Tinca 
Published: December 2023

Abstract
Professional autonomy, the latitude practitioners have in carrying out their occupational duties, is essential to journalism. This study, which examines how precariously employed journalists of the millennial generation in Slovenia perceive their professional roles, how professional autonomy plays out in practice, and how they advocate for better working conditions over time, draws on in-depth interviews conducted in 2017 and 2021. The findings reveal that journalists initially viewed their role as context-specific watchdogs helping the weak. However, journalists faced challenges to their autonomy that limited their ability to translate this role into practice. Most journalists did not consider it worthwhile to unite collectively to improve working conditions, leading to a gradual deterioration of professional autonomy. We propose the term ‘boiled watchdogs’ likening their situation to a frog slowly boiling over time. This article contributes to the international literature on precarity and professionalism in journalism in a post-socialist context.
Large biloma as the initial presentation of gallbladder perforation: a case report and literature review
Authors: Limani Nimetula , Misimi Shqipe , Nikolovski Andrej 
Published: December 2023

Abstract
Biloma is an encapsulated intra or extra-hepatic collection of bile after biliary tree trauma. Post-procedural and traumatic biliary damage are the most common etiologic causes. Gallbladder perforation due to acute cholecystitis rarely presents with biloma occurrence. We present a case of large extrahepatic biloma formation as a consequence of a perforated gallbladder.
Surgical treatment of Hahn–Steinthal fracture using Herbert screws
Authors: Saadi Yassine , Neqrachi Alae , Boufettal Moncif , Bassir Rida-Allah , Kharmaz Mohamed , Berrada Mohamed Saleh 
Published: December 2023

Abstract
Hahn–Steinthal fractures are rare and often neglected. Their initial management should be early, given the relatively high complication rate. We report eight cases of type I capitellum fractures treated by Herbert screw fixation. Between 2019 and 2022, we selected eight patients (six men and two women) with a mean age of 25 years (18–40 years). The mean follow-up was 2 years (1–3 years). Clinical results were assessed using the Mayo Clinic Elbow Performance Score (MEPS). The mean arc of mobilitý was 135° (105°–150°) for flexion/extension and 161° (150°–175°) for pronosupination. The mean MEPS was 90.6 points, with seven excellent results and one good result. The aim of this study was to highlight the good results of Herbert screw fixation technique in the management of Hahn–Steinthal fractures.
Successful management of primary sarcoma of the breast with complete pathological response: a case report
Authors: Arafat Hasan , Abulaban-Awar Ola , Fatayer Mohammad , Abufara Marwan 
Published: December 2023

AbstractPrimary sarcomas of the breast are extremely rare and heterogenous malignancies; they should be differentiated from phyllodes tumors. They are characterized by their high rate of recurrence, rapid growth and aggressive coarse. We present a case of a 41-year-old Palestinian female who presented with a recurrent breast mass. Biopsy showed primary sarcoma and imaging confirmed metastasis to axillary lymph nodes. The patient received six cycles of ifosfamide–adriamycin protocol resulting in complete pathological response. She underwent left sided modified radical mastectomy followed by radiation and six more cycles of the same protocol as adjuvant. Primary breast sarcomas are rare neoplasms that require multidisciplinary discussion to guide treatment. The approach to these tumors is chemotherapy followed by surgical resection when operable, in addition to local control via radiotherapy and adjuvant chemotherapy.
Three Years of the Coronavirus Disease 2019 Pandemic in a European Region: A Population-Based Longitudinal Assessment in Madrid Between 2020 and 2022
Authors: Berenguer Juan , Calvo-Alcántara María J , Alvaro-Meca Alejandro , Estévez José C , Basanta Miguel , Ruiz Sergio , Matáix Ángel L , Bienzóbas César , Cosano Lourdes , Silva Aura P , Salas Pilar , Gullón Pedro , Franco Manuel , Arribas José R , Molero José M , Hernán Miguel A 
Published: December 2023

Abstract

Background
Our objective was to assess the health impact of coronavirus disease 2019 (COVID-19) during 2020–2022 in the Madrid region.

Methods
We included all individuals registered in the Madrid Health System Registry as of 31 December 2019, and followed them until 31 December 2022. Using a unique personal identifier, we linked the databases of primary care, hospitals, pharmacies, certified laboratories performing diagnostic tests, vaccines, and mortality.

Results
Of 6 833 423 individuals, 21.4% had a confirmed COVID-19 diagnosis, and 1.5% had a COVID-19 hospitalization (primary diagnosis). Thirty-day mortality was 1.6% for confirmed COVID-19 (from 11.4% in first semester 2020 to 0.4% in first semester 2022). Thirty-day mortality was 10.8% for COVID-19 hospitalizations (from 14.0% in first semester 2020 to 6.0% in second semester 2022). There were 24 073 deaths within 30 days of a confirmed COVID-19 diagnosis. Advanced age, male sex, higher socioeconomic deprivation, and comorbidities were associated with higher mortality.

Conclusions
By linking administrative and clinical databases, we characterized the burden of the COVID-19 pandemic in Madrid over 3 years. Our analysis proposes a high-level framework for comparisons of the burden of COVID-19 across areas worldwide.
Scale-up of Direct-Acting Antiviral Treatment in Prisons Is Both Cost-effective and Key to Hepatitis C Virus Elimination
Authors: Shih Sophy T F , Stone Jack , Martin Natasha K , Hajarizadeh Behzad , Cunningham Evan B , Kwon Jisoo A , McGrath Colette , Grant Luke , Grebely Jason , Dore Gregory J , Lloyd Andrew R , Vickerman Peter , Chambers Georgina M 
Published: December 2023

Abstract

Background
The Surveillance and Treatment of Prisoners With Hepatitis C (SToP-C) study demonstrated that scaling up of direct-acting antiviral (DAA) treatment reduced hepatitis C virus (HCV) transmission. We evaluated the cost-effectiveness of scaling up HCV treatment in statewide prison services incorporating long-term outcomes across custodial and community settings.

Methods
A dynamic model of incarceration and HCV transmission among people who inject drugs (PWID) in New South Wales, Australia, was extended to include former PWID and those with long-term HCV progression. Using Australian costing data, we estimated the cost-effectiveness of scaling up HCV treatment in prisons by 44% (as achieved by the SToP-C study) for 10 years (2021–2030) before reducing to baseline levels, compared to a status quo scenario. The mean incremental cost-effectiveness ratio (ICER) was estimated by comparing the differences in costs and quality-adjusted life-years (QALYs) between the scale-up and status quo scenarios over 40 years (2021–2060) discounted at 5% per annum. Univariate and probabilistic sensitivity analyses were performed.

Results
Scaling up HCV treatment in the statewide prison service is projected to be cost-effective with a mean ICER of A$12 968/QALY gained. The base-case scenario gains 275 QALYs over 40 years at a net incremental cost of A$3.6 million. Excluding DAA pharmaceutical costs, the mean ICER is reduced to A$6 054/QALY. At the willingness-to-pay threshold of A$50 000/QALY, 100% of simulations are cost-effective at various discount rates, time horizons, and changes of treatment levels in prison and community.

Conclusions
Scaling up HCV testing and treatment in prisons is highly cost-effective and should be considered a priority in the national elimination strategy.

Clinical Trials Registration
NCT02064049.
Epidemiology, Risk Factors, and Prophylaxis Use for Pneumocystis jirovecii Pneumonia in the Non-HIV Population: A Retrospective Study in Québec, Canada
Authors: Quigley Nicholas , d’Amours Laurence , Gervais Philippe , Dion Geneviève 
Published: December 2023

Abstract

Background
Pneumocystis jirovecii pneumonia (PJP) remains a significant threat in immunocompromised cases. Recent data on epidemiology and risk factors for PJP in non-HIV cases are scarce, and guidelines on appropriate prophylaxis are lacking.

Methods
In this multicenter retrospective trial, all non-HIV adult cases admitted to hospitals in Québec City, Canada, between January 2011 and January 2021 with a diagnosis of PJP were assessed for eligibility.

Results
An overall 129 cases of PJP were included. More than two-thirds had an underlying hematologic disease or an autoimmune/inflammatory condition. Prior to diagnosis, 83.7% were taking corticosteroids, 71.3% immunosuppressive agents (alone or in combination with corticosteroids), and 62% both. A diagnosis of PJP was noted in 22 patients receiving corticosteroids for treatment &lt;28 days. Two patients developed PJP while undergoing corticosteroid monotherapy at a mean daily prednisone-equivalent dose &lt;20 mg/d; 4.7% of our cohort received a PJP prophylaxis. Current recommendations or accepted clinical practices for PJP prophylaxis would not have applied to 48.8% of our patients.

Conclusions
The use of corticosteroids—in monotherapy or in coadministration with other immunosuppressive agents—remains the principal risk factor for PJP in the non-HIV population. Current prophylaxis guidelines and accepted practices are insufficient to adequately prevent PJP and need to be broadened and updated.
Deuteronomy in the New Testament
Authors: Labahn Michael 
Published: December 2023

Abstract
The New Testament (NT) and its literary sources correspond to contemporary Judaism in the appreciation of the Deuteronomy. In nearly every NT writing, it is not only the explicit use of Deuteronomy in quotations that is important. Parallels between the Old and New Testaments show that Deuteronomy was mostly used next to the prophets, especially Isaiah, and the Psalms, shaped by the distinct understanding of Christ, worship of the one God, love for God and neighbor, the law as God’s life-enhancing will, and the figure of Moses and his liberation song. Moreover, NT’s use of Deuteronomy witnesses developments of the (Greek) text of Deuteronomy at that time, whereby influence of the NT on the text transmission of Septuagint is recognizable.
Modern Representations of the Wives of the Prophet Muḥammad
Authors: Khan Ruqayya Y. 
Published: December 2023

Abstract
The Wives of the Prophet Muḥammad (azwāj al-nabī), also known as the Mothers of the Believers (ummahāt al-mu’minīn), loom large in the traditional biography of Muḥammad ibn ʿAbd Allāh, and these female figures occupy an important role in the foundational phase of Islam. They also continued to hold importance for subsequent debates and polemics in early Islamic history, society and politics—even if through contested, refracted, and fragmented lenses. This chapter analyzes these women as Wives, and less as the Mothers of the Believers, since undoubtedly these two different sobriquets, though they refer to the same subset of women, entail different associations and modes of assessments. The chapter furthermore provides a review of relevant modern literature that discusses the Wives and exhumes in the process the various construals of the continuing significance of their lives in the modern period.
Muslim Women’s Religious and Social Activism in South Africa
Authors: Hoel Nina 
Published: December 2023

Abstract
The chapter examines the rich and composite terrain of Muslim women’s activism in South Africa. Presenting a selection of cases to illustrate topical research endeavors and central academic debates, the chapter considers theoretical issues and strategies prevalent in the South African context. The chapter presents three cases: (1) women in the mosque, (2) the struggle for Muslim personal law, and (3) queer Muslim lives in South Africa. Overall, the chapter argues that the analytical categories of experience and intersectionality, together with South African scholar Sa’diyya Shaikh’s useful concept of “tafsīr of praxis,” constitute central theoretical tenets that importantly mark Muslim women’s activism in South Africa.
Women’s Religious and Social Activism in South Asia
Authors: Shehabuddin Elora 
Published: December 2023

Abstract
This chapter focuses on different faith-based movements, that is, movements in which women’s identity as Muslim women, their personal piety, or their reliance on an Islamic framework to understand and seek to resolve a problem were paramount. It argues that although these different forms of activism have proven personally empowering to individual women or even small groups of women—for example, by enhancing their social networks and engagement, improving their access to religious texts, or allowing them to engage more deeply with their faith through adherence to strict dress codes and engagement in charitable deeds—in the end, these movements have not fought for women in an inclusive and progressive manner. Indeed, they have often supported policies and laws that discriminate against women, especially Muslim women who do not dress or pray like them.
Classical Exegeses on Key Qur’ānic Verses Concerning Women
Authors: Mubarak Hadia 
Published: December 2023

Abstract
Despite sweeping generalizations about the classical exegetical tradition’s perspectives on women and gender, few scholarly works have closely engaged classical exegetical texts on women and gender. This chapter explores primary sources of premodern Qurʾānic exegesis (tafsīr) of four verses that are critical to conceptualizations of gendered identities, hierarchies, and roles in the Muslim tradition: Qur’ān 4:1 on the origin of human creation; Qur’ān 2:228 on the reciprocal rights of husbands and wives, including men’s “degree” over women; Qur’ān 4:34 on the consequences of women’s nushūz; and Qur’ān 4:128 on the consequences of men’s nushūz. By illustrating the pluralism that is inherent to the genre of tafsīr, this chapter argues for a more nuanced engagement with classical exegesis that disrupts binary views of this tradition as either patriarchal or egalitarian.
Status of Muslim Women in Modern Family and Personal Law
Authors: Siddiqui Sohaira 
Published: December 2023

Abstract
The reform of Islamic family law in Organization of Islamic Cooperation countries over the last century has been fraught with tension and division. Beginning in the colonial period, and influenced by the wholesale legislative changes in Muslim countries, a series of dichotomies frame legal and policy debates on Islamic family law: traditional versus modern, religious versus secular, state versus civil society, and tradition versus reform. Scholars have differed in the construction of a theoretical framework to analyze the changes over the last century largely due to the differing responses of various actors. Consistent among these debates is the desire for reform of Islamic family law. This chapter explores the theoretical debates on reform and connects it to legislative changes and civil society organizations. The contemporary case studies of Morocco and Malaysia are used as examples.
Women’s Religious and Social Activism in Turkey
Authors: Maritato Chiara 
Published: December 2023

Abstract
In the past three decades, the multifaceted relationship between Islamist activists and secular feminists has shaped women’s religious and social activism in Turkey. A fascinating literature has assessed the significance of these bridges and influences that have created forms of cooperation since the 1980s. Stemming from this scholarship, the chapter problematizes how the incorporation of Muslim women in the Turkish state bureaucracy has affected women’s religious and social activism. Drawing on extensive ethnographic research on women employed as religious officers at the Presidency of Religious Affairs (Diyanet), it casts light on how Muslim women’s activism has been affected by the conservative gender regime which accompanied the current AKP’s authoritarian turn.
Women’s Religious and Social Activism in Egypt and North Africa
Authors: Allam Nermin 
Published: December 2023

Abstract
The chapter surveys some of the common themes that marked women’s social and religious activism and shaped its trajectory specifically in Egypt, and, more broadly, in North Africa. It highlights the nature of their early efforts, the shift in their activism, the overlap between secular and Islamic discourses in their intellectual grounding, and their international orientation and recent NGO-ization. It is particularly interested in analyzing how the literature approached and theorized these social and religious forms of participation and how the latter refashioned scholars’ thinking of agency and activism. Women’s engagement either in social welfare activities or Islamic inspired volunteerism, it argues, often blurred the dichotomy between the social, the political, and the religious, since it took place against complex backgrounds and grounded itself in overlapping discourses.