bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of conservative treatment on greater trochanteric pain syndrome: a systematic review and network meta-analysis of randomized controlled trials
Authors: Wang Si-Qi , Guo Ning-Yi , Liu Wei , Huang Hong-jie , Xu Bing-bing , Wang Jian-quan 
Published: January 2025

Abstract

Objective
Numerous studies have investigated conservative treatments for GTPS. However, there remains a lack of comparative analyses among treatment modalities, making it challenging to formulate the optimal conservative treatment strategy. This study aimed to compare conservative treatments for greater trochanteric pain syndrome (GTPS) in terms of their effectiveness in relieving pain and improving functional outcomes.

Methods
In accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, the PubMed, Embase, Cochrane Library and ClinicalTrials.gov along with other databases were searched to identify relevant studies. The quality of the selected studies was evaluated using risk of bias assessments, and the data were extracted. Network meta-analysis was performed using random effects models to evaluate the effects of treatment modalities on pain reduction and functional improvement. The evidence of the included studies was evaluated using the Grading of Recommendations, Assessment, Development, and Evaluations framework.

Results
Nineteen RCTs involving 1701 participants were included. The risk of bias was assessed using Cochrane ROB2. The results of network meta-analysis revealed that exercise therapy yielded the most significant improvement on reducing pain scores measured using the NRS and enhancing functional outcomes measured using the VISA-G. Additionally, injection therapy showed significant advantages in improving functional outcomes measured by using the Harris Hip Scale.

Discussion
This study confirmed the significant efficacy of exercise programs on pain reduction and functional improvement in GTPS patients. Additionally, we identified the positive effects of injection therapy and physical modalities on managing pain and enhancing functional outcomes among GTPS patients. Owing to the limited number of included studies, comparing the effects of different conservative treatments remains challenging. Future studies should expand the quantity of RCTs to identify the optimal conservative treatment strategy for GTPS.

Conclusion
This study reaffirmed the superiority of exercise therapy in the treatment of GTPS and revealed the effectiveness of injection and physical modalities. As the number of studies increase, we anticipate more reliable conclusions to further optimize conservative treatment strategies for GTPS. Ultimately, our study can help clinicians determine the optimal conservative treatment for GTPS and may spur future research on conservative treatments for tendinopathy.
Automated and code-free development of a risk calculator using ChatGPT-4 for predicting diabetic retinopathy and macular edema without retinal imaging
Authors: Choi Eun Young , Choi Joon Yul , Yoo Tae Keun 
Published: January 2025

Abstract

Background
Diabetic retinopathy (DR) and macular edema (DME) are critical causes of vision loss in patients with diabetes. In many communities, access to ophthalmologists and retinal imaging equipment is limited, making screening for diabetic retinal complications difficult in primary health care centers. We investigated whether ChatGPT-4, an advanced large-language-model chatbot, can develop risk calculators for DR and DME using health check-up tabular data without the need for retinal imaging or coding experience.

Methods
Data-driven prediction models were developed using medical history and laboratory blood test data from diabetic patients in the Korea National Health and Nutrition Examination Surveys (KNHANES). The dataset was divided into training (KNHANES 2017–2020) and validation (KNHANES 2021) datasets. ChatGPT-4 was used to build prediction formulas for DR and DME and developed a web-based risk calculator tool. Logistic regression analysis was performed by ChatGPT-4 to predict DR and DME, followed by the automatic generation of Hypertext Markup Language (HTML) code for the web-based tool. The performance of the models was evaluated using areas under the curves of receiver operating characteristic curve (ROC-AUCs).

Results
ChatGPT-4 successfully developed a risk calculator for DR and DME, operational on a web browser without any coding experience. The validation set showed ROC-AUCs of 0.786 and 0.835 for predicting DR and DME, respectively. The performance of the ChatGPT-4 developed models was comparable to those created using various machine-learning tools.

Conclusion
By utilizing ChatGPT-4 with code-free prompts, we overcame the technical barriers associated with using coding skills for developing prediction models, making it feasible to build a risk calculator for DR and DME prediction. Our approach offers an easily accessible tool for the risk prediction of DM and DME in diabetic patients during health check-ups, without the need for retinal imaging. Based on this automatically developed risk calculator using ChatGPT-4, health care workers will be able to effectively screen patients who require retinal examinations using only medical history and laboratory data. Future research should focus on validating this approach in diverse populations and exploring the integration of more comprehensive clinical data to enhance predictive performance.

Graphical Abstract
Surgical management options for childhood intracranial arachnoid cysts: a comparative study
Authors: Elmesallamy Wael Abd Elrahman Ali , Elbana Mohamed , Abaza Hassan , Fahmy Mohammed , Taha Mahmoud M. 
Published: January 2025

Abstract

Background
The symptomatic and incidentally discovered childhood intracranial arachnoid cysts may make it challenging to define the best management option, which may be surgical or observational. The best surgical option is still in debate, either regarding the type or the indication of surgery. This study aims to evaluate cysto-peritoneal shunts, endoscopic fenestration, and our technique of microsurgical partial excision of the cyst wall with maintenance of subarachnoid patency as surgical treatment options for childhood intracranial arachnoid cysts.

Results
This retrospective study was performed to compare three surgical options for treatment of childhood intracranial arachnoid cysts during the period from January 2015 to October 2022, with a follow-up of at least one year. These options included a cysto-peritoneal shunt, endoscopic fenestration, and microsurgical patency of the subarachnoid space without basal fenestration. Clinical improvement rating and operative complications showed insignificant differences between the three surgical options; however, total disappearance of the arachnoid cysts was significantly associated with the microsurgical option (p = 0.0312).

Conclusion
Surgical management of childhood arachnoid cysts either by cysto-peritoneal shunt, endoscopic fenestration, or microsurgical techniques was efficient according to the accessibility of the cysts, and the microsurgical patency of the subarachnoid space had the most significant effect on the disappearance of the cysts.
Prognostic Models From Transcriptomic Signatures of the Tumor Microenvironment and Cell Cycle in Stage III Colon Cancer From PETACC-8 and IDEA-France Trials
Authors: Gallois Claire , Sroussi Marine , André Thierry , Mouillet-Richard Sophie , Agueeff Natacha , Mulot Claire , Vernerey Dewi , Louvet Christophe , Bachet Jean-Baptiste , Dourthe Louis-Marie , Mazard Thibault , Jary Marine , Coutzac Clélia , Lecaille Cédric , Tabernero Josep , Van Laethem Jean-Luc , Lepage Côme , Emile Jean-François , de Reyniès Aurélien , Taieb Julien , Laurent-Puig Pierre 
Published: January 2025

PURPOSE
The objective of this work was to establish prognostic models in stage III colon cancer (CC) on the basis of transcriptomic signatures of the tumor microenvironment (TME) and cell cycle from the PETACC-8 (training set) and IDEA-France (validation set) trials.

PATIENTS AND METHODS
3'RNA sequencing was performed in 1,733 patients from the PETACC-8 trial and 1,248 patients from the IDEA-France trial. Four transcriptomic signatures were analyzed: T-cell and macrophage M2 signatures, the expression of CXCL13, and a score on the basis of the Oncotype DX CC Recurrence Score using the same formula from the stromal score and the cell cycle score. The Immune Proliferative Stromal (IPS) score was defined as the number of dichotomized signatures that fall under the category of a dismal prognosis (from 0 to 4). Time to recurrence (TTR) was defined as the time from the date of random assignment to local and/or metastatic relapse and/or death because of CC, whichever occurs first.

RESULTS

High Oncotype-like and M2 scores and low CXCL13 expression and T-cell score were associated with a shorter TTR. A multivariable model including these signatures and all known prognostic factors applied to the IDEA-France cohort by obtaining a value of this model for each patient showed TTR significantly different depending on the quartile of this value and a 3-year rate of patients without recurrence ranging from 56% for the lowest quartile to 89% for the highest quartile (
P
< .0001). The IPS score was significantly associated with TTR in multivariable analysis.

CONCLUSION
Using transcriptomic data of patients with stage III CC from two large-scale adjuvant trials, a prognostic model on the basis of signatures of the TME and the cell cycle provides important information in addition to known prognostic factors for patient stratification on risk of recurrence.
Tο αναπηρικό κίνημα και ο αγώνας για αναγνώριση: Συνθήκη για μετασχηματίζουσα μάθηση ατόμων με αναπηρία
Authors: Χατζηπέτρου Ανθή 
Published: January 2025

Η διδακτορική διατριβή που παρουσιάζεται εκπονήθηκε στη Σχολή Ανθρωπιστικών Επιστημών του Ελληνικού Ανοικτού Πανεπιστημίου και υποστηρίχθηκε τον Ιούνιο του 2023. Η τριμελής συμβουλευτική επιτροπή συγκροτήθηκε από τον Επίκουρο Καθηγητή του Ελληνικού Ανοικτού Πανεπιστημίου Ζαχαρία Παληό (επιβλέπων), τον Καθηγητή του Πανεπιστημίου Κρήτης Γιώργο Τσιώλη και τον Ομότιμο Καθηγητή του Πανεπιστημίου Αθηνών Γεράσιμο Κουζέλη. Στη διατριβή εξετάζεται η σύνθετη σχέση μεταξύ βιογραφίας, μάθησης και (δια)μόρφωσης.
Managing Channel Profits with Positive Demand Externalities
Authors: Gao Long , Jian Dawei , Gumus Mehmet , Mishra Birendra K. 
Published: January 2025

Demand externalities arise when past sales stimulate future demand. They pervade many consumer markets. To penetrate such markets, how should manufacturers contract with retailers? We formulate the problem as a dynamic game, wherein the retailer can privately observe and control evolving market conditions, and consumers can act either myopically or strategically. Our contribution is threefold. (i) We characterize the optimal contract: It resolves a dynamic tradeoff between exploiting demand externalities, screening new information, and optimizing channel efficiency; moreover, it has a simple implementation of quantity discount. (ii) We characterize the dual role of demand externalities. Although demand externalities can improve channel surplus by expanding market size, they can also exacerbate information friction by enhancing the retailer’s ability to manipulate the market. Ignoring the dark side of the agency cost, previous studies may have overestimated the benefit of demand externalities. (iii) We provide new practical guidance. We show private information per se need not hurt channel efficiency: The manufacturer can use recursive advance selling to extract new information for free. Our results also shed light on when and why manufacturers should moderate demand externalities and prefer long-term contracts. By highlighting the dual role of demand externalities in long-run channel performance, this study sharpens our understanding of channel theory and practice. This paper was accepted by Dmitri Kuksov, marketing. Funding: L. Gao was partly supported by Academic Senate COR Grants of UCR. Supplemental Material: The online appendices are available at https://doi.org/10.1287/mnsc.2021.00008 .
Social and Individual Influences on ATV and UTV Operating Practices of Young Adult Agricultural Workers
Authors: Barnett Kaleigh , Rudolphi Josie , Rohlman Diane 
Published: January 2025

HighlightsOver 50% of the young adult agricultural workers surveyed reported never wearing a helmet, seatbelt, or hearing protection when operating an ATV or UTV.Young adult agricultural workers’ mean ATV and UTV safety scores ranged from 1 to 4.44 on a scale of 1 to 5.Gender, supervisor influence, and risk-taking behaviors significantly influenced young agricultural workers ATV and UTV safety scores.Abstract. ATV and UTV crashes are a leading cause of agricultural-related injury and death in the United States. Young adult agricultural workers (under the age of 25) contribute substantially to the agricultural workforce and often utilize ATVs and UTVs in their work. However, it is unknown if they have adopted recommended safe operating behaviors that could reduce the potential for injury or death. As such, we evaluated young adult agricultural workers’ reported ATV and UTV operating practices and safety influences. Agricultural students from four Midwestern colleges and universities responded to an online survey about ATV and UTV operating behaviors, social influences (supervisor, peer, and parental risk-taking behaviors), and individual risk-taking orientation and tendencies. An ATV/UTV safety score was calculated from participants’ responses, and linear regression methods were used to examine associations between scores and other aspects of risk-taking. Out of 193 respondents, a large proportion of participants reported never wearing hearing protection (68.6%), a seatbelt (59.2%), or a helmet (58.1%) while operating an ATV or UTV. The analysis identified gender (p &lt; 0.001), global risk-taking (p = 0.001), risk-taking orientation at work (p = 0.012), and supervisor influence (p = 0.015) as significant factors influencing young adult agricultural workers’ safety scores. The findings suggest that gender, individual risk-taking tendencies, and supervisor influence play crucial roles in safety behavior, indicating that risk management initiatives for young adult agricultural workers should not only focus on individual behavior change but also consider the broader social and workplace influences on safety. Keywords: Agriculture, Behaviors, Health, Occupational, Safety, Young adults.
Using a Farm Safety Checklist to Assess Learner Performance Following a Safety Education Training
Authors: Toole Ruth D. , Vincent Stacy K. , Byrd Alex Preston , Namkoong Kang , Song Yongwook , Sprayberry Sarah R. 
Published: January 2025

HighlightsPercent agreement score showed moderate acceptability in preparing participants to complete the SFS application.Using self-directed learning to guide the training provided evidence for successful SFS application completion.Researchers plan to modify the self-directed learning approach to increase future SFS training success rates.Abstract. This study evaluates the use of Self-Directed Learning (SDL) and Performance-Based Assessment (PBA) to improve the accuracy of adult educators' completion of the Safe Farm Steward (SFS) application. PBA is a form of assessment commonly utilized in youth education, but there is limited evidence of its implementation among adults. Through implementing SDL, the researchers introduced a farm safety model to extension agents, agriculture teachers, and college professors to improve their performance assessment. The cohort attended a three-day professional development training followed by farm visitations; the training and visitations employed materials that incorporated SDL techniques. This study’s findings indicate that the professional development training was moderately acceptable in preparing the cohort to accurately complete the SFS application. Though the cohort did not meet the expected score on each individual construct, the overall PBA demonstrated moderate acceptability compared to the expected score. The researchers highlight gaps in professional development where recommendations for improvement could be made. Keywords: Agricultural education, Extension, Faculty, Farm safety, Performance-based assessment, Self-directed learning.
Late initiation of antenatal care visit amid implementation of new antenatal care model in Sub-Saharan African countries: A multilevel analysis of multination population survey data
Authors: Mare Kusse Urmale , Andargie Gashaye Gobena , Moloro Abdulkerim Hassen , Mohammed Ahmed Adem , Mohammed Osman Ahmed , Wengoro Beriso Furo , Lahole Begetayinoral Kussia , Hadaro Tesfahun Simon , Leyto Simeon Meskele , Mamo Petros Orkaido , Hedato Abdulhakim Hora , Seifu Beminate Lemma , Wondmeneh Temesgen Gebeyehu , Ebrahim Oumer Abdulkadir , Sabo Kebede Gemeda 
Published: January 2025

Introduction
Although late initiation of antenatal care has been linked with adverse pregnancy outcomes, a significant number of pregnant women in resource-limited regions are seeking this care late. There has been a lack of information on the extent and factors influencing late initiation of antenatal care in the African context following the implementation of the new antenatal care model in 2016. Thus, we aimed to determine the pooled prevalence of late antenatal care visit and its determinants among women in Sub-Saharan Africa (SSA) using national surveys conducted after the implementation of new guidelines.

Methods
We analyzed data from the recent demographic and health survey (DHS) conducted in 16 SSA between 2018 and 2022 using a weighted sample of 101,983 women who had antenatal care follow-up during their index pregnancy. A multilevel logistic regression models were fitted and likelihood and deviance values were used for model selection. In the regression model, we used adjusted odds ratios along with their corresponding 95% confidence intervals to determine the factors associated with late antenatal care visit.

Results
The pooled prevalence of late antenatal care visit among pregnant women in SSA was 53.8% [95% CI: 46.2% - 61.3%], ranging from 27.8% in Liberia to 75.8% in Nigeria. Women’s age and education, working status, partner’s education, health insurance coverage, birth order, household wealth, age at marriage, decision on health care, residence, and community-level women’s illiteracy were the factors associated with late antenatal care visit.

Conclusion
More than half of pregnant women in SSA initiated attending antenatal care during late pregnancy, with significant differences seen among countries. These results underscore the necessity for focused interventions to tackle these issues and enhance prompt access to antenatal services for better maternal and child health outcomes in the area. Moreover, creating tailored interventions for younger women, those with multiple previous births, employed women, and those who experienced early marriage to address their specific challenges and obstacles in seeking care is crucial.
Development of a mental health-related structural stigma measurement framework in the healthcare system setting: A modified Delphi study
Authors: Gurung Dristy , Subedi Bhawana , Kohrt Brandon A. , Wahid Syed Shabab , Rai Sauharda , Thornicroft Graham , Gronholm Petra C. 
Published: January 2025

Introduction
There is a worldwide dearth in literature on the nature, causes, and consequences of structural stigma in mental healthcare. This study aimed to address this gap by exploring key components for measuring structural stigma in healthcare system settings.

Methods
We used a modified Delphi method consisting of 3 rounds with global experts (stigma researchers, persons with lived experiences of mental health conditions (PWLEs), and policymakers). In the first round, indicators identified through a literature review (n = 39 studies) were appraised through expert consultation workshops with 22 panellists, including 54.5% women, 41% PWLEs, and 68.2% from low-and-middle income countries (LMICs). Round 2 (n = 53 panellists; 51% women, 8.3% PWLEs, and 56.6% from LMICs) involved ranking indicators through an online survey, and Round 3 (n = 58 panellists; 46% women, 21.7% PWLEs, and 60.4% from LMICs) involved re-ranking the results from Round 2. Smith’s salience index was calculated to measure consensus and Kendall’s coefficient of concordance to determine the degree of agreement. Narrative opinions and feedback from panellists during all three Delphi rounds were also sought.

Results
A list of indicators within five core measurement domains was identified in Round 1. Round 2 results were heterogeneous as indicated by the low to moderate salience of most indicators. Round 3 resulted in 4–5 indicators in each domain, that were ranked as highly salient by the expert panellists. Experts also provided narrative feedback on the definition of structural stigma, barriers to its measurement, domain-specific comments, and indicators-specific comments.

Conclusion
The framework aids in defining mental health-related structural stigma in healthcare and framing it in terms of inequities within healthcare system structures. These structures result in negative experiences of PWLEs and limit their access to quality healthcare. This conceptualization, informed by PWLE and stakeholders in LMICs, makes it easier to measure structural stigma and monitor changes in diverse healthcare settings around the world.
War at the Margins: Indigenous Experiences in World War II, Lin Poyer (2022)
Authors: Mückler Hermann 
Published: January 2025

Review of: War at the Margins: Indigenous Experiences in World War II, Lin Poyer (2022)
Honolulu, HI: University of Hawai‘i Press, 330 pp.,
ISBN 978 0 82489 182 4 (pbk), $28.00
ISBN 978 0 82489 181 7 (hbk), $68.00
Grasping structural racism from the field
Authors: Carlos Rita 
Published: January 2025

Based on a review of literature and field studies in penal institutions, this article proposes ways of analyzing the effects of racializing (di)visions (re)produced by justice actors in France today as in the past. While structural racism leads non-White youth to be over-incarcerated, they become the scapegoat of dysfunctions and failures of the (para)carceral system as the motor of its extension andhardening. Linking the criminal justice system to the national slavery and colonial enterprise helps us see the historical role of the State in this racially selective violence and seize the trickledown racism at play on the field, from higher-level officials to subordinate employees, targeting young poor afro-descendants and defining their trajectories.