bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical effect of virtual reality combined with drug therapy on patients with schizophrenia in convalescence
Authors: Guo Liang , Zhang Jingqi 
Published: October 2023

BackgroundSchizophrenia is a complex mental illness. At present, traditional drug therapy is the main method of schizophrenia management, but the treatment of many patients is not effective. Virtual reality (VR), a technology that simulates real environments, has begun to gain traction in the treatment of mental illness in recent years. The purpose of this study is to enhance the clinical therapeutic effect of patients in the recovery period through virtual reality technology combined with drug use.Subjects and MethodsThe study adopted a randomized controlled trial design and selected a group of patients with schizophrenia in a certain hospital as subjects. The experimental group received virtual reality combined with drug treatment, while the control group received only traditional drug therapy. After the experiment, the patients were evaluated for psychological symptoms, quality of life, and cognitive function. The results were statistically analyzed by SPSS23.0.ResultsThe results showed that the experimental group had significant advantages in improving psychological symptoms and life quality and restoring cognitive function. Compared to the traditional treatment group, patients in the experimental group were able to better control the production of hallucinations and delusions in the virtual reality environment and showed better adaptability in daily life.ConclusionsIn the recovery period of schizophrenia patients, virtual reality combined with drug therapy has shown remarkable clinical effects, providing an innovative auxiliary treatment for schizophrenia treatment。AcknowledgementJilin Provincial Department of Education Science and Technology Research Project; “Development and application of VR virtual roaming system in the ancient city of Neuin, Paektu Mountain” (No. JJKH20221304KJ); Changchun Guanghua College Youth Research Fund Project; Jilin Province Cultural Relics Restoration and Roaming System Based on VR Technology (No. QNJJZD2019004).
New sports rules combined with sertraline on Posttraumatic Stress of volleyball players
Authors: Wang Zhen 
Published: October 2023

BackgroundIn competitive sports, trauma and stress reactions are common problems faced by athletes. In order to explore methods to alleviate post-traumatic stress, research focuses on the effectiveness of combining new sports rules with medication treatment.Subjects and MethodsThe study selected 66 volleyball athletes with post-traumatic stress as the research subjects and divided them into an experimental group and a control group. The athletes in the research group received training on new sports rules and personalized sertraline therapy. The control group of athletes continued to receive traditional sports rules training and received placebo treatment at the same dose and time. During the research process, a standardized post-traumatic stress scale was used to evaluate the two groups. Collected data were processed and analyzed by the statistical method SPSS22.0.ResultsAfter a period of experimentation, the volleyball players in the research group showed a decrease in their PTSD scores from the initial score of 80 to 55 after being treated with the new sports rules combined with sertraline. The players in the control group, after receiving traditional sports rules and placebo treatment, experienced a decrease in their PTSD scores from an initial score of 90 to 75.ConclusionsThe research results indicate that the combination of new sports rules and personalized drug therapy has a significant positive impact on post-traumatic stress athletes. New rules and drug therapy can effectively alleviate athletes’ post-traumatic stress response.
Aesthetic ability cultivation on autistic college students in music education psychology
Authors: Liu Jinji 
Published: October 2023

BackgroundAutistic patients often exhibit social impairments and have a longer recovery period. The cultivation of musical aesthetic ability will expand the interests and hobbies of the trainees and alleviate social pressure. Therefore, the cultivation of musical aesthetic ability can be used in research on treating students with autism.Subjects and MethodsIn order to analyze the effectiveness of cultivating musical aesthetic ability in the treatment of autism among college students, the study randomly selected 60 college students with autism and divided them into two groups. One group is a blank group, which only receives conventional treatment. The other group is the experimental group, where patients in the experimental group receive routine treatment while also developing their musical aesthetic abilities. Two groups of experimental personnel were evaluated using the Children’s Autism Rating Scale (CARS) and the Kirschner Autism Behavior Scale (CABS) before and after the experiment.Results
Before the experiment, the CARS scores of the blank group and the experimental group were 34.83 ± 1.25 and 33.46 ± 2.06, respectively. After the experiment, the scores changed to 30.26 ± 2.81 and 28.16 ± 2.05, respectively. In the evaluation of the CABS scale, the scores of the blank group and the experimental group before the experiment were 16.26 ± 2.06 and 16.59 ± 1.75, respectively. After the experiment, the scores of the two groups were 15.73 ± 1.74 and 13.71 ± 2.05, respectively.ConclusionsThe cultivation of musical aesthetic ability in vocal music teaching in universities has an excellent therapeutic effect on autism among college students.
Art appreciation teaching reform in higher education on college students’ anxiety disorders
Authors: Feng Dakang 
Published: October 2023

BackgroundAt present, the problem of anxiety disorders among college students is becoming increasingly serious. The study aims to analyze the therapeutic effect of the reform of art appreciation teaching in colleges and universities on the anxiety disorder of college students.Subjects and MethodsThis study selected college students of a university as research subjects and divided them into an experimental group and a control group. The experimental group received the reform of art appreciation teaching in colleges and universities, and the control group continued traditional teaching. Data were processed using the statistical data analysis software SAS, and the t-test was used to assess the treatment effect.ResultsThe experimental group was significantly lower than the control group in the degree of anxiety (M=2.68 in the experimental group, M=3.92 in the control group, P<0.001). After the treatment, the anxiety level of students in the experimental group was significantly reduced, which indicates that the reform of art appreciation teaching has a positive effect on the treatment of anxiety disorders.ConclusionsThe results of the study show that the reform of art appreciation teaching in colleges and universities has a significant effect in treating anxiety disorders in college students. This provides useful information for colleges and universities to promote the development of relevant teaching reforms and psychological support measures to alleviate college students’ anxiety disorders and promote their mental health and personal development.
Positive effect analysis of combining five education concepts on mixed depression among college students
Authors: Ma Qiong 
Published: October 2023

BackgroundMixed-type depression among college students is a common mental health problem. The concept of simultaneous development of the five educations emphasizes comprehensive quality education and has been widely applied in higher education.Subjects and MethodsStudents selected from a university are the research subjects and are divided into an experimental group and a control group. The experimental group received comprehensive quality education that conforms to the concept of simultaneous development of the five educations, including academic education, physical exercise, moral cultivation, artistic cultivation, and social practice; The control group continued to receive traditional academic education. The study collected students’ depression scores and mental health questionnaire survey data as research indicators and used Stata statistical software for data processing and analysis.ResultsThe depression scores of the experimental group students significantly decreased. The specific numerical change data shows that the depression score of the experimental group students decreased from the initial 24.5 to 16.3, while the depression score of the control group students decreased from the initial 25.2 to 20.1.ConclusionsThe research results indicate that the concept of combining five educations has a positive effect on college students. The implementation of comprehensive quality education, including academic education, physical exercise, moral cultivation, artistic cultivation, and social practice, can effectively reduce the occurrence and degree of mixed depression among college students.AcknowledgementThe graduate education research project of Southwest Jiaotong University in 2020 (No. yjg4-2020-tz03-1).
Psychological and emotional communication practices towards schizophrenic patients in the mainstream media under big data
Authors: Liu Zhu 
Published: October 2023

Background
With the advent of the era of big data, the financial media space has become an important platform for mainstream media to carry out information dissemination. Schizophrenia is a serious mental illness, and sufferers often face social discrimination and psychological distress. For mainstream media, how to effectively disseminate information about schizophrenia in the era of big data, and how to guide the public to have a correct understanding and compassion for patients, is an urgent problem to be solved.Subjects and Methods
Based on big data, this study selects reports, comments and user comments about schizophrenia from mainstream media, and collates and analyzes these data through SPSS23.0, so as to explore the psychological and emotional communication mode and effect of mainstream media on schizophrenia patients.ResultsIt can be seen from the analysis that there are exaggerations and distortions in some mainstream media reports on patients with schizophrenia, leading to misunderstandings and fears of the public. Moreover, the report on schizophrenic patients lacks in-depth understanding and care, and only focuses on the news value of cases, ignoring the humanistic care and social integration of patients.ConclusionsIn the era of big data, popular science and education on mental diseases should be strengthened to reduce discrimination and exclusion of patients. At the same time, mainstream media should enhance their sense of social responsibility, avoid misleading and discriminatory reports, and provide more support and help for patients with schizophrenia.
Correlation between criminal responsibility ability and mental health status of offenders with deficient schizophrenia
Authors: Tan Junhua 
Published: October 2023

BackgroundThere are many clinical symptoms in patients with schizophrenia, among which the most common positive psychiatric symptoms are hallucinations and delusions. When clinical doctors diagnose patients with schizophrenia, they usually rely on the emotional or behavioral disorders they experience, which cannot be diagnosed through internal medicine. Due to the lack of standardized neuropathological standards for schizophrenia, it is necessary to diagnose schizophrenia patients through multiple behavioral approaches. The Positive and Negative Syndrome Scale (PANSS) can be used to analyze the mental health status and attack risk of offenders with schizophrenia in determining their criminal responsibility.Subjects and MethodsThis study selected 40 offenders with defective schizophrenia as the research subjects. According to the PANSS evaluation criteria, two psychiatrists trained in PANSS were used to evaluate patients with schizophrenia.ResultsThe research results show that the PANSS score of criminal patients with schizophrenia is significantly lower than the national norm score (P<0.05). The above research results show that mandatory supervision of criminals with schizophrenia can greatly control the speed of their disease development and effectively alleviate the delay of their condition.ConclusionsIn summary, PANSS can effectively identify criminals with schizophrenia, help regulators effectively identify criminals with schizophrenia, and provide a reliable basis for clinical diagnosis and judicial appraisal.
Assessment of emotional distress in palliative care: Edmonton Symptom Assessment System-revised (ESAS-r) vs Distress Thermometer
Authors: Ascencio Huertas Leticia , Allende Pérez Silvia Rosa , Peña Nieves Adriana 
Published: October 2023

AbstractObjectivesTo evaluate the sensitivity and specificity of the Distress Thermometer (DT) as a screening tool for emotional distress in oncological palliative care patients and to compare the DT with the Edmonton Symptom Assessment System-revised (ESAS-r) and the gold standard to determine the most appropriate assessment method in palliative psychological care.MethodsData were collected from psychological screening tests (ESAS-r and DT), and clinical interviews (gold standard) were conducted by a clinical psychologist specialist in palliative oncology from January 2021 to January 2022 in an oncology palliative care service.ResultsThe sample consisted of 356 first-time patients with a diagnosis of advanced cancer in palliative care. The most frequently reported oncological diagnoses were gastrointestinal tract (49.3%) and breast (18.3%). Most patients were female (n = 206; 57.9%), 60.4% were married/with a partner, 55.4% had between 6 and 9 years of schooling, and a median age of 57 (range, 46–65) years. The cutoff of the DT was 5, with a sensitivity of 75.88% and specificity of 54.3%. Emotional problems (sadness and nervousness) had a greater area under the curve (AUC) when measured using the DT than the ESAS-r; however, only in the case of the comparative sadness and discouragement was the difference between the AUC marginally significant.Significance of resultsThe use of the DT as a screening tool in oncological palliative care is more effective in the evaluation of psychological needs than the ESAS-r. The DT, in addition to evaluation by an expert psychologist, allows for a more comprehensive identification of signs and symptoms to yield an accurate mental health diagnosis based on the International Classification of Diseases-11th Revision and/or Diagnostic and Statistical Manual of Mental Disorders-Fifth Edition.
Development of nuclear microsatellite markers in Yerba mate (Ilex paraguariensis A. St. Hil.) from whole-genome sequence data
Authors: Tassano Carolina , Olano Rodrigo A. , Gaiero Paola , Vaio Magdalena , Speranza Pablo R. 
Published: October 2023

AbstractIlex paraguariensis A. St.-Hil. (yerba mate) (Aquifoliaceae Bercht. & J. Presl) is a plant species with great economic and cultural importance because its leaves are processed and ground to make infusions like mate or tereré. The species is distributed in a continuous area that includes Southern Brazil and part of Paraguay and Argentina. Uruguay represents the Southern distribution limit of the species, where small populations can be found as part of ravine forests. Although there are previous reports of molecular markers for this and other species in the genus, the available markers were not informative enough to represent the intra- and interpopulation genetic diversity in marginal Uruguayan populations. In this study, we developed highly informative polymorphic microsatellite markers to be used in genetic studies in I. paraguariensis. Markers were identified in contigs from the genome sequence of two individuals and then tested for amplification and polymorphism content in a diverse panel. Markers which passed these filters were tested on populations from Uruguay. They detected higher diversity within populations (in terms of number of alleles and heterozygosity) than previously reported, and levels of heterozygosity similar to those reported for two Brazilian populations. This subset of seven markers were successfully multiplexed, substantially reducing the costs of the analysis. Combined with previously reported nuclear and plastid markers, they can be used to evaluate the genetic diversity of rear-edge populations, identify genotypes for paternity studies and provide relevant information for the conservation and management of germplasm.
The Constructor’s Approach to the Problem
Authors: Marsh H A 
Published: October 2023

LADIES AND GENTLEMEN,Before calling on the first lecturer this afternoon, I would like to take this opportunity, on behalf of the Helicopter Association, of thanking the President and Council of the Royal Aeronautical Society for their courtesy, in inviting us to share to-day’s proceedings The idea of a full day’s discussion on helicopters originated with the R Ae S, but it can hardly be a coincidence that all those invited to read papers are members—I should say Founder Members—of the Helicopter Association, three of them being Council Members and one an ex-Council Member You are no doubt all aware that the Helicopter Association is of comparatively recent formation and owes a big debt of gratitude to the Royal Aeronautical Society, and other bodies for all the help and guidance they have given in the three years since the Association was incorporated
Some Speculations on the Aeroelastic Problems of Rotary Wing Systems
Authors: Collar A R 
Published: October 2023

This afternoon we are about to hear a lecture entitled ‘Some Speculations on the Aeroelastic Problems of Rotary Wing Systems’ This sounds a terrifying title—rather like the sub-titles of Victorian novels—but I suggest the short title, ‘Collar on Blade Flutter’ I have the pleasant task of introducing to you the lecturer In view of Professor COLLAR’S reputation, I am really not sure whether I should introduce the lecturer to the Association or the Association to the lecturer I shall therefore do both without, I hope, imposing upon your patienceProfessor COLLAR is easily introduced, because he is one of those people who hold their jobs After taking his degree in Cambridge, he served for 12 years on the staff of the N P L, and for 4 years at the R A E, before being invited to become the Sir George White Professor of Aeronautical Engineering in the University of Bristol
General Principles of the Structural Design of Helicopter Blades
Authors: Owen J B B 
Published: October 2023

SummaryIn designing rotor blades their strength on the ground, their torsional stiffness, their aerodynamic shape and smoothness, etc, have all to be considered, but the primary purpose of rotor blades is to sustain helicopters in controlled flight in the air, and one of the most difficult problems arising is that of assessing the bending stresses to which rotor blades are then subjected The present treatment is, therefore, largely concerned with the estimation of the bending stresses to which rotor blades are subject in flightThe loads tending to bend blades are first taken as being identical with those to which an idealised inflexible blade is subjected These loads are analysed along and perpendicular to the blade length, and equations for the bending equilibrium of flexible blades in the lift and drag planes are developed Difficulties associated with the solution of these equations are overcome by the construction of special solutions, called “Type Solutions,” which satisfy these equations and the end support conditions of the blade These type solutions give a physical picture of the problem and help in the calculation of blade stressesThe differences between the loads on an idealised inflexible blade and flexible blades are discussed In the lift plane it is demonstrated that they are, in general, small, but the possibility of dynamic amplification of higher harmonics in the loading system is brought out, and it is suggested that there may be a need for further work on this aspect of the problem, particularly for high speed helicopters
The Construction of Resin-Bonded Composite Type Rotor Blades, etc
Authors: King E P 
Published: October 2023

The advantages of constructing resin-bonded composite metal/wood or metal/fibrous helicopter blades, according to the design and by the “cold” assembly process developed by the author, may be summarised as followsIt is easy to demonstrate from first principles and also from the results of many tests that metal-clad sandwiches, suitable for helicopter rotor blade faces, fuselage shells, and many other aircraft components, may be designed with a bending stiffness from 10 to 40 times the stiffness of a simple sheet of metal of the same specification, size and weight This means, of course, that for an aerodynamically loaded surface, the spacing of ribs, stringers or other substructural members may be up to about three times that for the simple sheet with equal flexural deformation A simple calculation will give the weight-saving which can be effected by the elimination of such supporting members—and this saving would be available for further stiffening of the surface if desired
Ram-Jet Motors for Helicopters
Authors: Spalding D. B. 
Published: October 2023

SummaryThis paper examines the problems involved in designing the combustion system of a ram-jet motor for mounting on the tips of helicopter blades. Although sufficient knowledge is not yet available for such a motor to be completely designed on the drawing-board, a principle of construction is suggested which should require the minimum of experiment and development. The principle is illustrated by consideration of a 60 h.p. motor for a tip-speed of 650 ft./sec.
microRNA profilings identify plasma biomarkers and targets associated with pediatric epilepsy patients
Authors: Wang Qi , Shi Xulai , Li Ping-Ping , Gao Li , Zhou Yueyuan , Li Luyao , Ye Hao , Fu Xiaoqin , Li Peijun 
Published: October 2023

Abstract
Background
Although previous studies show that microRNAs (miRNAs) can potentially be used as diagnostic markers for epilepsy, there are very few analyses of pediatric epilepsy patients.

Methods
miRNA profiles using miRNA-seq was performed on plasma samples from 14 pediatric epileptic patients and 14 healthy children. miRNA miR-27a-3p that were significantly changed between two groups were further evaluated. The potential target genes of miR-27a-3p were screened through unbiased mRNA-seq and further validated using Western blot and immunohistochemistry in HEK-293T cells and in the brains of mice with epilepsy induced by lithium chloride–pilocarpine.

Results
We found 82 upregulated and 76 downregulated miRNAs in the plasma from pediatric patients compared with controls (p < 0.01), of which miR-27a-3p exhibited a very low p value (p < 0.0001) and validated in additional plasma samples. Two genes, GOLM1 and LIMK1, whose mRNA levels were decreased (p < 0.001) with the increase of miR-27a-3p were further validated in both HEK-293T cells and in epileptic mice.

Conclusions
MiR-27a-3p exhibits potential as a diagnostic and therapeutic marker for epilepsy. We postulate that additional studies on the downstream targets of miR-27a-3p will unravel its roles in epileptogenesis or disease progression.

Impact

A total of 158 differentially expressed miRNAs were detected in plasma between epileptic and control children.

Plasma miR-27a-3p was one of the miRNAs with a low p value.

GOLM1 and LIMK1 were validated as downstream target genes of miR-27a-3p.

miR-27a-3p has potential as a diagnostic and therapeutic marker for epilepsy.