bluuebunny/crossref_metadata_2025_split huggingface dataset:
Federalism A Way to Govern Globalization
Authors: Levi Lucio 
Published: February 2024

Globalization is a social and economic integration process, which has a significant political meaning, i.e. the erosion of state sovereignty. Thenature of globalization is not a mere quantitative increase of social relations and exchanges at world level, but it is a qualitative change rooted in the scientific revolution of material production, and it creates, alongside national societies and markets, a global market and a global civil society. It is a process that is changing the form and size of economic and social life and imposes on all sectors of social life a much wider dimension than that of sovereign states, even the biggest ones. The changes that have occurred in the sovereign state and the international system of states are by now recognized as the central political fact of our times. The construction of a general theory of politics that unifies political science and international relations is a long term task that may be performed by an entire generation of scholars. Multitudes of scholars are working to reconstruct a theory of politics that adheres more to the evolution of contemporary history. Federalism is one of these theories: it is an unfinished project, not a static political vision nor a timeless political theory. It is an unaccomplished project, which is constantly evolving in response to the new problems which history is raising relentlessly. Flexibility – which is the specific character of federal institutions – is particularly adapted to answering the need of combining unity with diversity that is required by the globalization era. Therefore, federalism is a political tool suitable for governing the social transformations under way in the contemporary world. It appears to be a very efficient institutional device for political integration, for ensuring the functioning of pluralistic societies, for protecting minorities, for solving ethnic, religious and national conflicts, and for answering the need for peace and international solidarity.
Remote assessment and monitoring with advanced wound therapy to optimise clinical outcomes, access and resources
Authors: Lee Aliza , Woodmansey Emma , Klopfenstein Benjamin , O'Leary Jessica L , Cole Windy 
Published: February 2024

Objective: Patients in rural communities may have limited access to wound care; however, this may be mitigated by using a shared care approach. This study assessed the impact of a remote assessment and monitoring tool in combination with adjunctive continuous topical oxygen therapy (cTOT) in patients with diabetes and hard-to-heal wounds. Method: Patients with hard-to-heal wounds (defined as no visible improvement in the previous four weeks) were enrolled to this 12-week pilot study to validate a shared care approach using an Advanced Digital Wound Care Platform-telehealth (ADWCPt) system (eKare Inc., US) coupled with cTOT. Patient and wound assessments were reviewed by the clinician either remotely, via telehealth calls, or at the clinic, and the number of face-to-face clinic visits was recorded. Patient health status scores were captured before and after the study, along with feedback on usability of the remote platform and cTOT device. Results: The wounds in all eight patients studied reduced in size over 12 weeks (mean percentage area reduction 92.0%), and two wounds were completely re-epithelialised. Another wound almost healed (99.2% wound area reduction). Clinical interactions consisted of self-assessments (n=80, 50.0%), video assessments with the clinician (n=27, 16.9%), and face-to-face interactions in clinic (n=53, 33.1%). Operational efficiencies encompassed a 54.0% increase in the number of clinical interactions, whereas clinical time was reduced by 25.8%. Health status scores improved across all eight patients and feedback on the shared approach and cTOT device was favourable. Conclusion: A shared care model with ADWCPt coupled with an innovative cTOT device saved time and resources, improving patient access and engagement, along with a marked improvement in the wound healing trajectory.
Angularly stable terahertz multiband LiNbO3-polymer hybrid metamaterial for microfluidic refractive index sensing
Authors: Ma Tao , Su Linxing , Fan Yabo , Wang Wenqian , Liu Heng 
Published: February 2024

A terahertz (THz) LiNbO3-polymer hybrid metamaterial (LPHM) consisting of three-layer Au patterns and two medium interval layers is demonstrated, and the bulk refractive index (RI) sensing performance is also studied. The parameter optimizations and sensing performances of the LPHM are simulated by the finite-element method (FEM). The results show that the reflection or absorption spectrum of the LPHM has four peaks in the 1–10 THz band, and the peaks move toward the lower frequency when the period (P) of the LPHM or the side length (a) of the notched square frame increases but shift to the higher frequency when w1 or w2 increases. Moreover, the LPHM has a wide angular stability and good structural stability. The sensing performance shows that the LPHM can achieve an RI sensitivity of 11.5 µm/RIU with a detection limit (DL) of 2.9×10−4RIU. The LPHM has potential applications in pharmacological biodevices, THz immunosensing, modern medical and clinical practices, and detection of thin films and biochemical substances, and it can be expected to realize multiphysical parameter measurements.
Current approaches addressing oral health practitioners’ responsiveness to child abuse and neglect: A scoping review protocol
Authors: Han Heuiwon , Koziol-McLain Jane , Morse Zac , Lees Amanda B. 
Published: February 2024

Introduction
Child abuse and neglect (CAN) poses significant risks, causing severe and long-lasting effects on a child’s well-being, including physical and mental health and learning and socializing capabilities. Oral health practitioners (OHPs) uniquely position themselves to identify signs of maltreatment in the orofacial area, offer appropriate support, and collaborate with a multidisciplinary team. The literature has shown that OHPs under-report child protection concerns to a statutory child protection agency. Responding to CAN is often hindered by various factors, such as the fear of making false accusations and insufficient knowledge to detect and report potential cases. However, the literature lacks a comprehensive understanding of the strategies and interventions that can address the responsiveness of OHPs and other professionals to child protection issues. This scoping review aims to provide a broad overview and map the literature on the existing approaches to enhance the responsiveness of OHPs in child protection.

Materials and methods
The proposed scoping review will be conducted following the JBI methodology for scoping reviews guideline and reported using the PRISMA-ScR guideline. The first exploratory search is conducted to refine the search strategy and inclusion and exclusion criteria. The second search will include MEDLINE (EBSCO), CINAHL (EBSCO), Dentistry & Oral Science Source (EBSCO), Cochrane Library, and Scopus, with a date range from January 2000 to March 2023. The third search will involve reference list searching and gray literature searching in Google and Google Scholar. Government and international health organizations’ websites will be searched for policies and guidelines. The review will consider studies that report the current approaches to address OHPs’ responsiveness to CAN in any setting. Two reviewers will independently select sources and extract data. Any disagreements will be resolved by consensus of the research team. The extracted data will be presented in a tabulated chart with a narrative summary.
Impact of two endotracheal tube fixation on the incidence of peri-oral lesions: Elastic adhesive strips versus cord in a protective sheath. Study protocol for a cluster cross-over randomized trial
Authors: Zinzoni Vanessa , Planche Lucie , Le Potier Sophie , Robin Laurence , Le Parco Cécile , Terrat Philippe , Leroyer Marie-Hélène , Atger Romain , Dauvergne Jérôme E. , Muller Lucie , Fontaine Laetitia , Morand Célina , Dennemont Pascaline , Paillard Ophélie , Vastral Servane , Dardaine Baptiste , Le Guillou Sylvie , Maquigneau Natacha , Martin Stéphanie , Lachérade Jean-Claude 
Published: February 2024

Background
Endotracheal tube fixation in ventilated patients must be appropriate to ensure security during mechanical ventilation and prevent skin lesions. The incidence of endotracheal tube‐caused pressure ulcers ranges from 7% to 45%. Various endotracheal tube fixations are used in intensive care units (ICUs) worldwide. By pressure exercised on the skin, these systems could lead to mucosal and skin peri-oral lesions. The main objective of this study is to evaluate the impact of the two fixation systems most commonly used in French ICUs (adhesive elastic band versus fixation cord with PolyVinyl Chloride (PVC) sheath) on the incidence of these peri-oral skin lesions.

Methods
This studyis a multicenter, open-label, controlled, superiority, cluster cross-over randomized trial. 768 patients will be recruited in the 16 ICUs involved. The inclusion of patients will be carried out over two 12-month periods. Each site begins with one of the evaluated fixation systems: elastic adhesive tape or cord associated with a protective sheath. After a 4-month break, each site switches to the other fixation system. The primary outcome is the development of at least one peri-oral lesion during the first ten days of maintaining an orally inserted endotracheal tube. The presence of lesions is assessed by a blinded adjudication committee using photographs taken daily.

Discussion
This study is the first multicenter, randomized trial designed to evaluate the impact of elastic adhesive tape versus fixation cord with PVC sheath on the incidence of peri-oral lesions. The results will provide data which could change and standardize care practices.

Trial registration
https://www.clinicaltrials.gov. Reference number: NCT04819425.
Auto-Brewery Syndrome After COVID-19 Infection
Authors: Yates Sarah R. , Saito Akira 
Published: February 2024

ABSTRACT
Auto-brewery syndrome (ABS) is a rare medical condition, wherein gut microbiota ferment carbohydrates to alcohol. Risk factors for ABS include diets high in carbohydrates and sugars, diabetes mellitus, prior gastrointestinal surgery, nonalcoholic fatty liver disease, and certain genetic mutations, among others. We provide a case of ABS that developed after known COVID-19 infection, which may be one of the contributing factors to its development.
Nintedanib-Induced Colitis Can Mimic Inflammatory Bowel Disease
Authors: Odah Tarek , Karime Christian , Hashash Jana G. , Farraye Francis A. 
Published: February 2024

ABSTRACT
Nintedanib is a medication that has been increasingly used for treatment of idiopathic and progressive pulmonary fibrosis. In this case series, we describe 3 patients with colitis symptoms associated with nintedanib use. Nintedanib discontinuation resulted in symptomatic resolution in all patients. Budesonide decreased symptoms in 1 patient. Clinicians should be vigilant in taking a thorough medication history and include nintedanib as a cause for gastrointestinal symptoms including colitis.
Subjetividades encontradas
Authors: Alonso Luciano 
Published: February 2024

En el presente texto se argumenta que las resistencias, negaciones o impugnaciones a las memorias que condenan en Argentina el terror de Estado de 1975-1983, pueden referenciarse por un lado a los componentes autoritarios de la sociedad, exacerbados en un proceso de polarización política, y por el otro a una más amplia subjetividad neoliberal.
Tras un largo proceso de luchas iniciado en la etapa de la transición a la democracia, las memorias propuestas por el movimiento por los derechos humanos llegaron a ser hegemónicas en Argentina. Pero en la última década ese predominio fue puesto en cuestión. Recurriendo a diversas fuentes de información, se destaca la emergencia cada vez más frecuente de memorias antidemocráticas y a favor de la represión. El texto concluye con consideraciones acerca de la interpretación que puede darse a ese proceso en atención a variables complejas, incluyendo la producción social de las subjetividades.
Filme für die Zukunft
Authors: Boelens Marlo , Förstner Dirk , Hänger Christian 
Published: February 2024

Zusammenfassung
Technische Entwicklungen haben das Bundesarchiv veranlasst, die Sicherung von Filmen durch Umkopieren auf neue Filmrollen zu beenden. Zukünftig erfolgt die langfristige Sicherung ausschließlich in digitaler Form, auch wenn die Filmrollen weiterhin unter klimatisierten Bedingungen aufbewahrt werden. Am Standort Hoppegarten werden alle Arbeitsschritte der digitalen Postproduktion vom Audio- und Filmscannen über die Lichtbestimmung bis zum Mastering angeboten.
PTTG1 induces pancreatic cancer cell proliferation and promotes aerobic glycolysis by regulating c-myc
Authors: Wang Yong , Hu Jianping , Chen Chen , Li Yongbo 
Published: February 2024

Abstract
This study aimed to clarify the role of pituitary tumor-transforming gene 1 (PTTG1) in proliferation, migration, invasion, and aerobic glycolysis of pancreatic cancer cells, and evaluate the potential of PTTG1 as a therapeutic target. PTTG1 expression in pancreatic cancers was analyzed using the GEPIA databank. In the Panc1 cell with the PTTG1 knockdown or Mia-PaCa2 cells with PTTG1 overexpression, the cell proliferation was evaluated using cell viability curves and colony formation, and wound heal assay and transwell assay were performed to evaluate the migration and invasion, respectively. Furthermore, a western blot was performed to evaluate the expressions of PTTG1, proliferating cell nuclear antigen, E-cadherin, N-cadherin, and c-myc. Meanwhile, the glucose uptake, extracellular acidification rates (ECAR), and oxygen consumption rates (OCR) were analyzed. Our results showed that PTTG1 expression is upregulated in pancreatic cancer, which promoted cell proliferation. Low PTTG1 contributed to higher disease-free survival and overall survival. In Panc1 cell, PTTG1 knockdown resulted in reduced cell viability and colony formation. The migration and invasion abilities of the cells were also reduced in Panc1 with PTTG1 knockdown. Correspondingly, PTTG1 knockdown decreased c-myc expression, glucose uptake, ECAR, and OCR in Panc1 cells. In Mia-PaCa2 cells, PTTG1 overexpression promoted cell proliferation, aerobic glycolysis, and translocation of β-catenin to the nucleus by regulating c-myc. In conclusion, PTTG1 induces proliferation, migration, and invasion, and promotes aerobic glycolysis in pancreatic cancer cells via regulating c-myc, demonstrating the potential of PTTG1 as a therapeutic target.
Role of serum B-cell-activating factor and interleukin-17 as biomarkers in the classification of interstitial pneumonia with autoimmune features
Authors: Zhao Lihong , Liu Li , Liu Yehua , Zheng Hong , Jiang Ping 
Published: February 2024

Abstract
Interstitial pneumonia with autoimmune features (IPAF) is a type of interstitial lung disease (ILD) with immune features that do not meet the diagnostic criteria for specific connective tissue diseases (CTDs). This retrospective case–control study investigated the role of serum B-cell-activating factor of the tumor necrosis factor family (BAFF) and interleukin (IL)-17 as biomarkers for IPAF. The differences in serum BAFF, IL-17, and IL-10 were compared among patients with idiopathic pulmonary fibrosis (IPF), IPAF, ILD associated with CTD (CTD-ILD), and healthy controls. The patients were treatment naïve. The correlations of BAFF with IL-10, IL-17, and pulmonary function were analyzed. The classifiable value of BAFF for IPAF was examined. The results showed that the serum levels of BAFF and IL-17 in the IPAF and CTD-ILD groups were higher than in the IPF group. High BAFF levels and high predicted diffusion capacity of the lungs for carbon monoxide (DLCO) were independent predictive factors for IPAF vs IPF. In the IPAF and CTD-ILD groups, serum BAFF levels were negatively correlated with predicted values of forced vital capacity (FVC%) and diffusing capacity of the lungs for carbon monoxide (DLCO%) and positively correlated with serum IL-17 and IL-10 levels. The cutoff value of combined BAFF and IL-17 was 0.704, and the sensitivity and specificity for classifying IPAF were 78.9 and 95.7%, respectively. In conclusion, combining serum BAFF and IL-17 as a biomarker may have classifiable value in differentiating IPAF from other forms of ILD.
A case of Trousseau syndrome: Screening, detection and complication
Authors: Liu Hui , Jiang Meng , Wu Nan , Liu Qingxin , Fan Xueli 
Published: February 2024

Abstract
Trousseau syndrome (TS) is a malignant tumor-mediated complication of the hypercoagulable state with an unknown etiology. Laboratory testing results in patients with TS have indicated elevated D-dimer levels. The imaging analysis in patients who had undergone stroke has shown the presence of several cerebral infarction lesions in multiple regions. Since patients have had malignant tumors for a long time when they suffer from a secondary stroke, the optimum time for radical tumor treatment is usually missed. This study reports a case to improve the early screening and detection of TS and reduce the risk of recurrence of cerebral infarction.
Preparation of Cu2+/TA/HAP composite coating with anti-bacterial and osteogenic potential on 3D-printed porous Ti alloy scaffolds for orthopedic applications
Authors: Haitao Xu , Siyuan Li , Sutong Guo , Yu Guo , Peirong Xu , Ling Wang , Yujian Ding , Dehong Feng 
Published: February 2024

Abstract
Because of stress shielding effects, traditional titanium (Ti) alloy scaffolds have a high elastic modulus, which might promote looseness and bone disintegration surrounding the implant, increasing the likelihood of a second surgery. In contrast, 3D-printed porous Ti alloy scaffolds can reduce the scaffold weight while enhancing biocompatibility. Further, these scaffolds’ porous nature allows bone tissue ingrowth as well as strong pore connectivity, which can improve nutrient absorption. Nevertheless, bare Ti alloy implants may fail because of inadequate bone integration; hence, adding a coating on the implant surface is an effective technique for improving implant stability. In this study, a composite coating comprising hydroxyapatite (HAP), chitosan (CS), tannic acid (TA) and copper ions (Cu2+) (Cu2+/TA/HAP composite coating) was prepared on the surface of 3D printed porous Ti alloy scaffolds using electrophoretic deposition. Using the standard plate count method, Live/Dead bacteria staining assay, FITC Phalloidin and 4′,6-diamidino-2-phenylindole staining assay, and live/dead staining of cells we determined that the composite coating has better antibacterial properties and cytocompatibility as well as lower cytotoxicity. The Alkaline Phosphatase assay revealed that the coating results showed good osteogenesis potential. Overall, the composite coatings produced in this investigation give new potential for the application of Ti alloys in clinics.
On the correspondence between periodic solutions of differential and dynamic equations on periodic time scales
Authors: Tsan Viktoriia , Stanzhytskyi Oleksandr , Martynyuk Olha 
Published: February 2024

Abstract
This paper studies the relationship between the existence of periodic solutions of systems of dynamic equations on time scales and their corresponding systems of differential equations.
We have established that, for a sufficiently small graininess function, if a dynamic equation on a time scale has an asymptotically stable periodic solution, then the corresponding differential equation will also have a periodic solution.
A converse result has also been obtained, where the existence of a periodic solution of a differential equation implies the existence of a corresponding solution on time scales, provided that the graininess function is sufficiently small.
Fully automated chemiluminescence microarray immunoassay for detection of antinuclear antibodies in systemic autoimmune rheumatic diseases
Authors: Yuan Dandan , Yang Xue , Ji Chen , Sun Guo , Xu Yang , Cao Ye , Ye Yan , Wang Tingting , Hu Zhigang 
Published: February 2024

Abstract

Objectives
Detection of specific antinuclear antibodies is very important in term of diagnosis, prognosis and management of patients with systemic autoimmune rheumatic diseases. Chemiluminescence microarray immunoassay (CLMIA) is a microdot array-based method that allows simultaneous detection of multiple antinuclear antibodies, which received increasing attention.

Methods
A CLMIA method that can detect 14 kinds of antinuclear antibodies was established and optimized. Basic performance and diagnostic performance of CLMIA was evaluated by comparing it with line immunoassay (LIA) and indirect immunofluorescence (IIF).

Results
Through conditional exploration, the optimal blocking time and blocking temperature were determined to be 18 h and 25 °C, respectively. The enzyme-labeled secondary antibody reaction concentration was 0.1 μg/mL, the incubation temperature of serum and enzyme-labeled secondary antibody were 30 °C, and the incubation time of serum and enzyme-labeled secondary antibody were 40 min. After parameter optimization, CLMIA demonstrated high accuracy with a relative bias <15 %; high sensitivity with detection limits below 3 IU/mL for dsDNA and below 1 RU/mL for other ANAs; and high reproducibility with both intra-assay and inter-assay coefficients of variation (CV) <15 %.The CLMIA detection method established in this study was also demonstrated to have good clinical diagnostic performance, showing the highest area under curve (AUC=0.87, p=0.042 and p=0.03). The CLMIA and LIA revealed substantial to good agreements on specific antinuclear antibodies except anti-dsDNA, with the Cohen’s kappa from 0.72 to 0.89. Samples that produced discrepant results between the CLMIA and LIA methods were further analyzed. Upon additional testing, most of these samples were ultimately determined to have been correctly detected by the CLMIA assay rather than the LIA assay, suggesting that CLMIA also shows some superiority in diagnosing dsDNA.

Conclusions
The CLMIA could become a potential routine method for detecting ANAs with the advantages of good detection performance.
Multifunctional hydrogels for wound healing
Authors: Yang Xinyu , Li Jinyan , Chen Xi , Wang Tao , Li Guifei , Zhang Kunxi , Yin Jingbo , Cui Haiyan 
Published: February 2024

Abstract
The process of wound healing is complex and dynamic. Given the unique nature of the skin, wound healing requires dressings that meet a wide range of functional requirements. Due to their unique structure and properties, hydrogel dressings provide ideal conditions for supporting the process of wound healing and can be enhanced with additional functions to meet the specific requirements of different types of wounds. Compared to traditional wound dressings, the newly developed hydrogel wound dressing offers several advantages, including its soft texture, ability to retain moisture, oxygen permeability, and comfort. With the advancement of medical technology, higher demands are being placed on the functionality of hydrogel dressings. Therefore, this paper offers a comprehensive overview of hydrogel wound dressings with various functions. These functions primarily include hemostatic hydrogel dressings, antibacterial hydrogel dressings, angiogenesis-promoting hydrogel dressings, and other functional hydrogel dressings. The paper also reviews the research and application of these dressings in recent years.