bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating Ergonomic Awareness in Dentistry: A Survey of Dental Students’ Knowledge During Operative Procedures
Authors: Kalaiarasi Maniarasu , Shobhana Ramu , Prakash Venkatachalam , Mitthra Suresh , Shalini H , Venkatesh Alagarsamy 
Published: January 2025

ABSTRACT

Aim:
The research aimed to explore students’ self-perceptions of their clinical work and identify challenges affecting their performance in restorative and endodontic treatments.

Materials and Methods:
The research was conducted among 157 dental students utilizing a self-designed, validated, closed-ended questionnaire.

Results:
The questionnaire received responses from 157 participants, including 88 undergraduates (UGs) and 69 postgraduates (PGs). Of these, 64% reported experiencing pain during clinical procedures, while 36% (n = 72) did not report any pain. Although 71.5% of students were aware of ergonomic posture, 28.5% of students were not. Despite this awareness, 64.5% of students found it challenging to maintain proper ergonomic postures while performing clinical tasks.

Conclusion:
Although most students know ergonomic postures, many struggle to maintain them during clinical procedures. Incorporating dental ergonomics into the curriculum is crucial to improving students’ well-being and efficiency.
Oral Health Misinformation on Youtube – A Content Analysis
Authors: Riyaz Mohammed Meera , Gousalya V , Anu V , Prashanth S , Ram S Prabhu , Varshini VJ Keerthi , Rajsanjay R 
Published: January 2025

ABSTRACT

Introduction:
With the rise of social media and widespread smartphone use, information is now readily accessible worldwide. However, the credibility of this information often remains unchecked. Few studies have evaluated oral health content on online platforms. However, YouTube, despite its popularity, is frequently overlooked. This study aims to identify and analyze oral health misinformation on YouTube.

Methods:
A search was done on YouTube using common keywords related to oral health through Google chrome browser with incognito mode to limit the bias associated with Google accounts. The videos obtained were subjected to analysis using a coding framework and both auditory and visual content were examined together by two coders to ensure a comprehensive coding process. All the videos were classified either as accurate information (useful) or misleading information.

Results:
A total of 72 videos were included in the study, of which about 55% of them had misleading content. About 75% of the videos containing misleading information were created by non-professionals and only about 15% of the videos containing misleading information were created by medical professionals. It was surprising to note that the misleading information had more positive engagement metric (137429) than the useful information (71207).

Conclusion:
From the content analysis, it was found that there was a large amount of misleading information on oral health in YouTube. Therefore, it’s crucial to address the potential risks of misleading content and to increase public awareness about the impact of following such misleading information.
In Silico toxicity assessment of Euphorbia hirta
Authors: Subramani Prabhu , Murugappan Senthil , Ganeshi Gajalakshm , Jones Sumathi , Mani Devi 
Published: January 2025

ABSTRACT

Background:
Herbs have evolved as an alternative and safer option in deriving antibiotics to combat antimicrobial resistance. Euphorbia hirta is a tropical weed. It possesses many beneficial medicinal values; the present study was undertaken to determine in silico toxicity of Eurphorbia hirta.

Materials and Methods:

In silico toxicity estimation was carried out using The Toxicity Estimation Software Tool (TEST). LC50 threshold was calculated using TEST software based on predictions from each model and the consensus average of the component models.

Results:
The phytoconstituents 3, 7, 11, 15-tetramethyl-2-hexadecen-1-ol, 9, 12, 15-octadecatrienoic acid, 9-octadecenamide, henicosane, hentriacontane, hexadecanoic acid, hexadecanoic acid, methyl ester, phytol, squalene, tetracosane, and Urs - 12- 2n-24-oic acid, 3-oxo-, methyl ester are nontoxic.

Conclusion:
Phytochemical constituents of Euphorbia hirta exhibit an acceptable toxicity limit for drug production and preclinical and clinical appraisal.
Fatigue Syndrome among Medical Students in Saudi Arabia: A Cross-Sectional Study on Depression and Anxiety
Authors: Alkhamees Abdulmajeed A. , Algubllan Lamees Abdulaziz , Alsughier Naif , Alwashmi Ahmad H. , Alamr Deem Tariq , Alharbi Aeshah Menawer , Alturaif Norah Abdullah 
Published: January 2025

ABSTRACT

Objective:
This cross-sectional investigation aimed to determine fatigue syndrome (FS) prevalence and its association with depression and anxiety among medical students in Saudi Arabia.

Materials and Methods:
An online survey was performed using a pretested questionnaire comprising four sections: sociodemographic information, the 11-item Chalder Fatigue Questionnaire (CFQ), the 9-item Patient Health Questionnaire (PHQ-9), and the Generalized Anxiety Disorder 7-item (GAD-7) scale. A total of 740 medical students participated in the cross-sectional study.

Results:
The study found that 56.4% of the students met the diagnostic criteria for FS, with female students (69.7%) showing higher FS prevalence compared to male students (30.3%). FS was significantly associated with symptoms of depression (r = 0.68, P < 0.001) and anxiety (r = 0.54, P < 0.001). Other factors associated with higher FS scores included higher body mass index, lack of physical activity, and a history of substance use.

Conclusion:
FS is highly prevalent among medical students in Saudi Arabia, particularly among females. The association between FS and mental health symptoms underscores the need for targeted interventions to manage FS and its psychological impact in this population.
Clinical Outcomes and Stroke Recurrence in Moyamoya Disease Post-Revascularization: A Retrospective Analysis
Authors: Alhumaid Alanoud , Taher Nouran , Alanazi Rahmah , Bensaeed Nora Z. 
Published: January 2025

ABSTRACT

Objectives:
This study aimed to assess the clinical characteristics, treatment outcomes, and recurrence risks in moyamoya disease (MMD) patients, focusing on the impact of revascularization and antiplatelet therapy.

Materials and Methods:
Forty-six MMD patients were analyzed. Data on demographics, clinical characteristics, treatment outcomes, and recurrence rates of ischemic and hemorrhagic strokes were collected. The effectiveness of revascularization and the role of antiplatelet therapy in preventing recurrent strokes were statistically evaluated.

Results:
The mean age was 19.5 years. Right-side weakness (28.3%) and left-side weakness (21.7%) were common symptoms. Pre-revascularization, recurrent ischemic strokes affected 58.7% of patients; post-revascularization, the incidence dropped to 8.7%. However, a high recurrence rate (39.1%) persisted among those not undergoing surgery. Post-revascularization hemorrhagic strokes were rare (6.5%). Antiplatelet therapy significantly reduced ischemic stroke recurrence (P < 0.001) and hemorrhagic stroke risk.

Conclusion:
Early intervention and continuous antiplatelet therapy are crucial in managing MMD. Despite reduced ischemic stroke recurrence post-revascularization, functional outcomes often remained unimproved, indicating the need for optimized treatment strategies.
Comparative Analysis of Fluoride Removal Efficacy of Drinking Water with Moringa Oleifera Seeds, Leaves and its Barks as Economic and Cost-Effective Bioadsorbents
Authors: Manikandan Saranya , Ramesh Maya , Yoithapprabhunath Thuckanaickenpalayam R. , Kalidhas Priya , Sundaram Manikandan , Krishnan Ramesh 
Published: January 2025

ABSTRACT

Background:
Fluorides are the most important pollutants present in the effluents from various industrial and groundwater sources. These are very poisonous to living beings and have a dangerous effect on their health. Fluoride in drinking water within permissible limits of 0.5-1.0 mg/L is useful for the production and of maintenance healthy, teeth and bones as extreme intake of fluoride causes dental and skeletal fluorosis. Thus the removal of fluoride using adsorbents is a main step towards the protection of environment.

Methods:
The water samples are collected from wells of Salem district. Previous to sampling, the water is left to run from the source for few minutes. The study for presence of fluoride in groundwater samples is carried out as per APHA standard methods. Fluoride concentration be determined with SPADNS method spectrometric ally by use zirconyl-SPADNS (sodium 2-(parasulphophenylazo)-1, 8-dihydroxy-3, 6-naphthalene-disulphonate) reagents.

Results:
The significant difference in average score is tested through the analysis of variance after testing the normality test and it shows there is highly significant difference is found in the Fluoride Removal with respect to Moringaoleifera seeds, Moringaoleifera leaves, Moringaoleifera barks since the p value is less than 0.01.

Conclusion:
Drinking water is an essential basic need. The use of adsorbents is simple, cheap, non-toxic and environmentally friendly, its adoption for the defluoridation of drinking water. Based on the results of this study, it can be concluded that the low-cost adsorbents are effective in removal of fluoride from water.
Smoking Behaviors and Health Risk Awareness Among Healthcare Students in Alkharj, Saudi Arabia
Authors: Almalki Sultan A. , Gowdar Inderjit M. , Alanazi Bashar A. , Alqahtani Osama A. , Alanazi Fahad R. , Al-Harbi Khalid F. 
Published: January 2025

ABSTRACT

Objective:
This study examines smoking behaviors, including the age of initiation, daily consumption, cessation attempts, and awareness of smoking-related health risks among male healthcare professional students in Alkharj, Saudi Arabia.

Methods:
A cross-sectional survey was conducted with 308 male students across four healthcare disciplines: Medicine, Dentistry, Nursing, and Pharmacy. A structured questionnaire collected data on smoking status, initiation age, daily cigarette consumption, reasons for smoking, cessation attempts, and awareness of systemic and oral diseases caused by smoking. Descriptive statistics and Chi-Square tests were used to identify significant differences among disciplines.

Results:
The prevalence of smoking varied significantly among the different disciplines, with Pharmacy students having the lowest smoking rate (16.2%) and Dental students the highest (38.5%) (P = 0.005). Most smokers began smoking between the ages of 18-21. The majority of smokers consumed 3-5 cigarettes per day. Awareness of smoking-related systemic diseases, such as lung cancer, was high across all groups, though knowledge of smoking-related oral diseases varied. Attempts to quit smoking were most prevalent among Dental students (66.7%), indicating a significant difference in cessation efforts across disciplines (P = 0.04).

Conclusion:
The study highlights significant differences in smoking behaviors and awareness across healthcare disciplines. These findings underscore the critical need for targeted educational interventions to address smoking behaviors and improve health literacy among healthcare professional students. By focusing on discipline-specific approaches, it is possible to enhance the effectiveness of tobacco control programs and promote healthier lifestyles among future healthcare providers.
Computational Studies on Recent Congeners of Fluoroquinolones and Nitroimidazoles for Their Use in Periodontal Therapy
Authors: Natarajan Prabhu Manickam 
Published: January 2025

ABSTRACT

Background:
Periodontitis is a slow progressing infection and has profound systemic implications. The influence of various therapeutic drugs to inhibit inflammation and promote bone regeneration has been studied. Introduction of newer congeners of older drugs necessitates testing the efficacy of newer drugs for the said use.

Aim:
The aim was to determine the effectiveness of newer nitroimidazoles and fluoroquinolones for controlling and eliminating periodontal pathology by binding to the targets.

Methods and Material:
A total of 12 drugs were selected, and the chemical structure drugs used were retrieved form PubChem and development of 2d and 3d structures was done using chem draw software. Targets used were Gingipain K, FimA, Interleukin-1β, and Estrogen Receptor β. AutoDock version 4 software was used for in silico docking simulations. The binding free energy, inhibition constant, electrostatic energy, intermolecular energy, and total interaction surface are all provided by the docking tool. In this paper, the optimal docking pose for each target is chosen and presented.

Results:
From the results of the study, it can be observed that gatifloxacin and ciprofloxacin have more affinity and interactions with all four targets were analyzed.

Conclusions:
This study has effectively tested nitroimidazoles and fluoroquinolones comparatively and proposed that fluoroquinolones are more effective for blocking periodontitis.
Decoding Mandibular Angle Fracture Management: Biomechanical Analysis of Different Plating Techniques – An In Vitro Study
Authors: Subramanian Adalarasan , Sambanthan Thiruneelakandan , Punithan Akash , Petchiammal S Meera , Laxmi R. Bhuvana , Srikanth Vishal , Eswar E 
Published: January 2025

ABSTRACT

Objective:
The primary rationale of the study is to assess the biomechanical aspects of Champy’s, monoplanar, biplanar, and 3D strut plating systems using an in vitro model in the management of the angle of mandible fracture.

Methods:
Thirty-two hemi-sectioned mandibles (N = 32) were obtained from adult goats and divided into four groups (N = 8) for different plating techniques: monoplanar, biplanar, Champy’s, and three-dimensional curved angle strut plating. A customized biomechanical test machine simulated masticatory loads by applying compressive forces. Force versus displacement data were recorded using an Instron Lloyd LRX machine.

Results:
Plating techniques with two plates exhibited higher resistance to displacement than single-plate techniques. The three-dimensional curved angle strut plate group had the highest mean compressive strength (184.7913 N), followed by biplanar plating (170.29 N), monoplanar plating (159.3419 N), and Champy’s plating (55.48375 N). Statistical analysis showed significant differences between the three-dimensional curved angle strut plating technique and Champy’s plating technique (P value ≤ 0.0016*), as well as between the biplanar plating technique and Champy’s plating technique (P value ≤ 0.0010*).

Conclusion:
The three-dimensional curved angle strut plate and biplanar plating techniques exhibited superior biomechanical performance compared to monoplanar and Champy’s plating techniques.
A Review of Contributing Factors to Heart Failure: Genetic, Lifestyle, and Environmental Influences
Authors: Thotakura Balaji , Vidya S , Sheena K. S , Roy D Dinesh , Prabhu K , Jones Sumathi 
Published: January 2025

ABSTRACT

Background:
: Heart failure (HF) is a multifaceted syndrome influenced by genetic, environmental, lifestyle, and comorbid factors. Understanding these diverse aspects is crucial for effective management and treatment. This systematic review aims to synthesize current evidence on the multifactorial aspects of HF, providing insights for comprehensive care strategies.

Methods:
This review involved a thorough literature search across databases such as PubMed, MEDLINE, and EMBASE, focusing on studies published up to January 2024. It included research examining the role of genetic predispositions, lifestyle factors, and comorbid conditions in HF. Studies were evaluated for quality by using standardized assessment tools, and a meta-analysis was conducted where applicable.

Results:
The review included 30 studies, covering diverse research designs and sample sizes. Key findings included the identification of genetic loci associated with HF, the impact of hypertension and lifestyle factors on HF progression, and the interplay of comorbid conditions such as diabetes in HF management. The studies collectively emphasized the complexity of HF, highlighting its multifactorial nature.

Conclusions:
The findings of this systematic review underscore the multifaceted nature of HF and the need for a comprehensive approach in its management. It points toward the importance of personalized medicine in HF, considering the interplay of various factors. Future research should focus on longitudinal studies with diverse populations to further understand the mechanisms underlying HF and develop targeted interventions.
Spectrum of Brain Imaging with 3T MRI for Infants with History of Perinatal Hypoxia and their Comparison with 128 Slice NCCT Images
Authors: Dwivedi Abhishek , Dakua Anita , Agarwal Mayank , Singh Satyender N. , Choudhury Binoy Kumar , Chaubey Deepika , Chaubey Abhishek 
Published: January 2025

ABSTRACT

Background:
Neonates with a history of perinatal hypoxia often require meticulous neuroimaging to detect brain injuries promptly. This study investigates the utility of 3T magnetic resonance imaging (MRI) in assessing neonates with perinatal hypoxia and compares it with the conventional 128-slice NCCT imaging modality.

Materials and Methods:
A retrospective study was conducted, encompassing 67 cases over 1 year from October 2022 to October 2023. We assessed the performance of 3T MRI using the Achieva 3T TX MRI scanner (Philips, The Netherlands) and compared it to the 128-slice GE 660 Optima CT scan.

Results:
We found that 3T MRI demonstrated remarkable sensitivity in detecting brain injuries in this population. Notably, it excelled in identifying subtle lesions, with white matter changes observed in 76.1% of cases, corpus callosum thinning in 64.2%, restriction of diffusion on DWI in 28.4%, signal loss on GRE in 14.9%, and cerebral venous thrombosis in 9% of the study participants.

Conclusion:
The integration of 3T MRI into neonatal neuroimaging protocols is crucial. It offers enhanced diagnostic accuracy and safety, supporting its inclusion as a fundamental component in neonatal care.
A Prospective Study Comparing the Use of Radiometric Measurements in CBCT and DEXA Scans of the Spine to Measure Bone Mineral Density in Postmenopausal Women
Authors: Mallick Sriram Chandra , Bhuvaneshwari S , Sangamesh N.C. , Mishra Silpiranjan , Bajoria Atul Anand , Singh Dhirendra Kumar 
Published: January 2025

ABSTRACT

Introduction:
This study evaluated BMD using radiomorphometric indices from conebeam computed tomography (CBCT) scans of the mandible, comparing them with dualenergy Xray absorptiometry (DEXA) scans of the spine.

Results:
The study emphasizes the robustness of DEXAderived T scores for assessing bone health and guiding treatment in postmenopausal women.
Change in the Morphology of Cell Pattern in Oral Mucosa Following Radiation Exposures to Various Radiographic Techniques
Authors: Jena Amrit , Kaur Awneet , Soundarya S , Mahay Pooja , Manohar Balaji , Bhuvaneshwari S. 
Published: January 2025

ABSTRACT

Introduction:
Ionizing radiation is extensively utilized in dental imaging research, with radiography serving as the primary diagnostic technique in dentistry.

Materials and methods:
The cytotoxic effects of Xrays are wellestablished, the genotoxic consequences remain debated.

Results:
This study aims to evaluate the impact of dental Xrays on cellular morphological patterns in the oral mucosa.
Assessment of Knowledge, Attitude, and Practice about “SADE” Among Dentists – A Cross-Sectional Study
Authors: Rajendran Madhumathy , Anandhan Vasanthakumari , Arumugam Selvabalaji , Archana S Preethi , Pandiyan Ramanandvignesh , Ramesh Archana 
Published: January 2025

ABSTRACT

Background:
Intellectual and developmental disabilities (IDDs), including autism spectrum disorder (ASD), often lead to sensory challenges and dental anxiety, complicating oral healthcare. Sensory adapted dental environment (SADE) can alleviate anxiety and enhance cooperation during dental procedures, but awareness and implementation among dentists remain limited.

Objective:
To assess general dentists’ knowledge, attitudes, and practices regarding SADE and identify gaps for targeted educational programs.

Methods:
A survey of 500 dentists in Tamil Nadu, India, collected data on demographics, SADE knowledge, attitudes, and practices. Analysis included descriptive statistics and significance tests.

Results:
Most respondents were female (68.6%), aged 21–30 (90.9%), with a BDS degree (76.0%), and having 1–10 years of experience (94.8%). Primary fears for children in dental settings were injections (45.7%) and white coats (41.8%). Nonpharmacologic techniques were preferred by 86.8% of dentists. While 49.5% were aware of SADE, only 30.3% had implemented it. Most recognized its benefits (78.7%) and believed it reduces anxiety (81.9%). Despite interest (84.7%), concerns about costs (53.0%) hindered implementation.

Conclusion:
Strong interest and perceived benefits of SADE exist among dentists, but cost concerns and limited understanding hinder its implementation. Enhanced education and resources are vital for broader SADE adoption, potentially improving dental care for individuals with IDDs.
Evaluation of the Transverse Strength and UV Spectrophotometric Analysis of the Residual Monomer Content of Autoclave Polymerized Conventional and High-Impact Heat-Cure Denture Base Resins—An In-Vitro Study
Authors: Roseline Savarimuthu Paulraj , Mathew Chalakuzhiyil Abraham , Gnanavel S Sakthi , Vengatachalam Vishnuvardhan , Kittuchami Dheepika , Gopalakrishnan Priyanka 
Published: January 2025

ABSTRACT

Background and Objective:
Inspite of advancements in material properties of heat cure acrylic resin, fracture of denture base and allergic reactions due to release of residual monomer is encountered frequently. To improve strength and to reduce residual monomer, different polymerization methods need to be investigated. The objective is to evaluate and compare transverse strength and residual monomer content of two different heat cured denture base resins polymerized by conventional water bath and by autoclave.

Materials and Methods:
Samples were prepared with Acralyn-H conventional heat cure resin and Acralyn-H super hi-impact resin using metal dies. Samples undergoing water bath polymerization were polymerized in water bath at 74°C for 2 hours followed by 100°C for 1 hour and samples undergoing autoclave polymerization were cured in an autoclave at 121°C and 210 kPa for 30 minutes as holding temperature. Transverse strength specimens were processed and then tested for transverse strength in a Universal testing machine. Specimens for residual monomer content estimation were weighed and each specimen’s residual monomer was extracted in methanol using Soxhlet extractor and then read at 230nm in Ultraviolet-Visible spectrophotometer. Concentrations of residual monomer were evaluated and weight fractions were calculated.

Results:
The results of this study showed a statistically significant difference in transverse strength of Acralyn-H conventional heat cure resin polymerized by autoclave, whereas all other groups showed a non-significant result.

Conclusion:
Autoclave can be used as an alternative polymerization technique as it has shown similar results when compared with water bath polymerization and the time required for polymerization was also reduced.