bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ethnic Disparities in COVID-19 Vaccine Mistrust and Receipt in British Columbia, Canada: Population Survey
Authors: Mahmood Bushra , Adu Prince , McKee Geoffrey , Bharmal Aamir , Wilton James , Janjua Naveed Zafar 
Published: December 2023

Background
Racialized populations in the United States, Canada, and the United Kingdom have been disproportionately affected by COVID-19. Higher vaccine hesitancy has been reported among racial and ethnic minorities in some of these countries. In the United Kingdom, for example, higher vaccine hesitancy has been observed among the South Asian population and Black compared with the White population, and this has been attributed to lack of trust in government due to historical and ongoing racism and discrimination.

Objective
This study aimed to assess vaccine receipt by ethnicity and its relationship with mistrust among ethnic groups in British Columbia (BC), Canada.

Methods
We included adults ≥18 years of age who participated in the BC COVID-19 Population Mixing Patterns Survey (BC-Mix) from March 8, 2021, to August 8, 2022. The survey included questions about vaccine receipt and beliefs based on a behavioral framework. Multivariable logistic regression was used to assess the association between mistrust in vaccines and vaccine receipt among ethnic groups.

Results
The analysis included 25,640 adults. Overall, 76.7% (22,010/28,696) of respondents reported having received at least 1 dose of COVID-19 vaccines (Chinese=86.1%, South Asian=79.6%, White=75.5%, and other ethnicity=73.2%). Overall, 13.7% (3513/25,640) of respondents reported mistrust of COVID-19 vaccines (Chinese=7.1%, South Asian=8.2%, White=15.4%, and other ethnicity=15.2%). In the multivariable model (adjusting for age, sex, ethnicity, educational attainment, and household size), mistrust was associated with a 93% reduced odds of vaccine receipt (adjusted odds ratio 0.07, 95% CI 0.06-0.08). In the models stratified by ethnicity, mistrust was associated with 81%, 92%, 94%, and 95% reduced odds of vaccine receipt among South Asian, Chinese, White, and other ethnicities, respectively. Indecision, whether to trust the vaccine or not, was significantly associated with a 70% and 78% reduced odds of vaccine receipt among those who identified as White and of other ethnic groups, respectively.

Conclusions
Vaccine receipt among those who identified as South Asian and Chinese in BC was higher than that among the White population. Vaccine mistrust was associated with a lower odds of vaccine receipt in all ethnicities, but it had a lower effect on vaccine receipt among the South Asian and Chinese populations. Future research needs to focus on sources of mistrust to better understand its potential influence on vaccine receipt among visible minorities in Canada.
Assessment of Heart Rate Monitoring During Exercise With Smart Wristbands and a Heart Rhythm Patch: Validation and Comparison Study
Authors: Wang Tse-Lun , Wu Hao-Yi , Wang Wei-Yun , Chen Chao-Wen , Chien Wu-Chien , Chu Chi-Ming , Wu Yi-Syuan 
Published: December 2023

Background
The integration of wearable devices into fitness routines, particularly in military settings, necessitates a rigorous assessment of their accuracy. This study evaluates the precision of heart rate measurements by locally manufactured wristbands, increasingly used in military academies, to inform future device selection for military training activities.

Objective
This research aims to assess the reliability of heart rate monitoring in chest straps versus wearable wristbands.

Methods
Data on heart rate and acceleration were collected using the Q-Band Q-69 smart wristband (Mobile Action Technology Inc) and compared against the Zephyr Bioharness standard measuring device. The Lin concordance correlation coefficient, Pearson product moment correlation coefficient, and intraclass correlation coefficient were used for reliability analysis.

Results
Participants from a Northern Taiwanese medical school were enrolled (January 1-June 31, 2021). The Q-Band Q-69 demonstrated that the mean absolute percentage error (MAPE) of women was observed to be 13.35 (SD 13.47). Comparatively, men exhibited a lower MAPE of 8.54 (SD 10.49). The walking state MAPE was 7.79 for women and 10.65 for men. The wristband’s accuracy generally remained below 10% MAPE in other activities. Pearson product moment correlation coefficient analysis indicated gender-based performance differences, with overall coefficients of 0.625 for women and 0.808 for men, varying across walking, running, and cooldown phases.

Conclusions
This study highlights significant gender and activity-dependent variations in the accuracy of the MobileAction Q-Band Q-69 smart wristband. Reduced accuracy was notably observed during running. Occasional extreme errors point to the necessity of caution in relying on such devices for exercise monitoring. The findings emphasize the limitations and potential inaccuracies of wearable technology, especially in high-intensity physical activities.
<i>In silico</i> Screening of Potential Antidiabetic Phenolic Compounds from Banana (<i>Musa</i> spp.) Peel Against PTP1B Protein
Authors: Pratama Rico Alexander , Astina Junaida , Parikesit Arli Aditya 
Published: December 2023

Type 2 diabetes mellitus (T2DM) is a global problem with increasing prevalence. The current treatments have made an immense progress with some side effects, such as drug resistance, acute kidney toxicity, and increased risk of heart attack. Banana (Musa spp.) peel comprises 40% of banana fruit contains high phenolic compounds whilst some studies have suggested a correlation between phenolic compounds and antidiabetic activity. One of the novel protein targets that has been identified as a potential anti-diabetic treatment is PTP1B (PDB ID:2NT7). Therefore, this study aimed to screen the potential PTP1B inhibitor for antidiabetic treatment from phenolic compounds in banana peel. QSAR, molecular docking, ADME-Tox, and molecular dynamics analysis were deployed to examine forty-three phenolic compounds in banana peel. Eighteen ligands were screened by QSAR analysis and eight of them had a lower binding energy than the standard (ertiprotafib) in molecular docking, with urolithin A and chrysin were the lowest. Both passed Lipinski’s rule of five, had a good intestinal absorption, and no blood-brain barrier penetration, however, their mutagenicity, carcinogenicity, and irritation to the skin and eyes were still in questions. Molecular dynamics analysis found both of them were in a stable conformation with PTP1B. This study suggested a potential of urolithin A and chrysin as PTP1B inhibitor for antidiabetic treatment. Additionally, further experimentation is required to validate this finding.
Associations of Angiopoietin 2 and Vascular Endothelial Growth Factor-A Concentrations with Clinical End Points
Authors: Mohebi Reza , Liu Yuxi , Hansen Michael K. , Yavin Yshai , Sattar Naveed , Pollock Carol A. , Butler Javed , Jardine Meg , Masson Serge , Heerspink Hiddo J.L. , Januzzi James L. 
Published: December 2023

Background
Angiopoietin 2 regulates endothelial function partially mediated by vascular endothelial growth factor-A (VEGF-A) and may play a role in diabetic kidney disease (DKD). We assessed the association of angiopoietin 2 and VEGF-A with cardiorenal outcomes and investigated the effect of canagliflozin on angiopoietin 2 and VEGF-A concentrations.

Methods
Two thousand five hundred sixty-five study participants with DKD and available plasma samples treated with canagliflozin or placebo in the Canagliflozin and Kidney Events in Diabetes with Established Nephropathy Clinical Evaluation (CREDENCE) trial were included. Angiopoietin 2 and VEGF-A concentrations were measured at baseline, year 1, and year 3. The primary composite end point of the trial was a composite of kidney failure, doubling of the serum creatinine level, and kidney or cardiovascular death.

Results
Patients with the highest baseline quartile of angiopoietin 2, but not VEGF-A, concentration had the highest risk clinical profile. Treatment with canagliflozin significantly lowered concentrations of angiopoietin 2 (adjusted geometric mean ratio: 0.94; 95% confidence interval, 0.92 to 0.95; P < 0.001), but not VEGF-A. In multivariable-adjusted modeling, each 50% increment in log baseline angiopoietin 2 concentrations was associated with a higher risk of primary composite outcome (hazard ratio, 1.27; 95% confidence interval, 1.13 to 1.43). Angiopoietin 2 change at year 1 compared with baseline explained 10% of the effect of canagliflozin on the primary composite outcome. VEGF-A concentrations were not associated with outcomes, alone or in combination with angiopoietin 2.

Conclusions
Higher angiopoietin 2 levels were associated with cardiorenal risk among individuals with DKD independent of VEGF-A. Canagliflozin lowered angiopoietin 2 concentrations.

Clinical Trial registry name and registration number
Evaluation of the Effects of Canagliflozin on Renal and Cardiovascular Outcomes in Participants With Diabetic Nephropathy, NCT02065791.
Modelo de cuidados crónicos sustentado en la salud digital: un análisis para investigación en enfermedad cardiovascular
Authors: Aranda-Sánchez D. , Sanhueza-Alvarado O. , Tíscar-González V. , Gutiérrez-Valverde J.M. 
Published: December 2023

Introducción: Las enfermedades cardiovasculares se encuentran entre las principales causas de morbimortalidad en los adultos a nivel mundial. Los últimos años evidencian los factores que obstaculizan el cuidado presencial de enfermería dirigido a estas personas, por tal motivo es necesario realizar investigaciones basadas en marcos teóricos que incluyan conceptos de enfermería y herramientas de salud digital para sustentar el cuidado en línea.
Objetivo: Analizar el modelo mejorado de cuidados crónicos de la eSalud y evaluar su efectividad en la investigación en enfermedad cardiovascular.
Metodología: Se usó el análisis de la Teoría de Walker y Avant para analizar el origen, significado, congruencia lógica, utilidad, parsimonia y transferibilidad del modelo.
Desarrollo del análisis teórico del modelo: Dicha herramienta es descriptiva, sus componentes son de nivel de abstracción alto, adecuados para explorar contextos y patrones de cuidado de los pacientes con enfermedad cardiovascular. Su estructura teórica permite establecer proposiciones factibles de ser probadas y aplicadas a la práctica de enfermería. La eEducación, la eComunidad, el circuito de retroalimentación completa y el apoyo al automanejo sustentan significativamente la investigación de enfermería con un enfoque desde la salud digital.
Conclusión: El modelo fundamentaría el cuidado de enfermería que se brinda al paciente con enfermedad cardiovascular vía digital, ya sea como un modo único o como complemento al cuidado presencial. Esto permitirá crear e implementar diseños informáticos para la entrega del cuidado y así contribuir al desarrollo del conocimiento de enfermería. El uso del modelo en investigación en enfermería fortalecerá el liderazgo innovador-tecnológico de la disciplina.
KONTAMINASI SOIL TRANSMITTED HELMINTHS PADA SAYURAN KUBIS DAN SELADA DI PASAR TRADISIONAL KOTA JAMBI
Authors: Putri Ulfadiya , Hanina Hanina , Fitri Amelia Dwi 
Published: December 2023

ABSTRACT
The transmission of Soil Transmited Helminths (STH) can occur by contaminated food of infective egg. The types of food most often contaminated such as cabbage and lettuce. This study aimed to find the contamination of STH eggs and identified the eggs type which contaminated in the traditional market of Jambi city. This study was a descriptive research which were done at Biomedical Laboratory of the Faculty of Medicine and Health Sciences of the University of Jambi on July-August 2018. Samples taken from three traditional market in the Jambi city that is Talang Banjar, Angso Duo, and Simpang Pulai market. Vegetable samples consisted of 9 cabbage and 9 lettuce from each market. Fifty gram samples were examined by the sedimentation method. There were STH eggs on 16 (29.6%) vegetable samples. The type of STH eggs which contaminated lettuce were Ascaris lumbricoides 6 (37.50%) samples, Ascaris lumbricoides and Trichuris trichiura 3 (18.75%) samples, Hookworm 2 samples (12.50%), and Trichuris trichiura 1 sample (6.25%). The type of STH eggs which contaminated cabbage were Ascaris lumbricoides 2 (12.50%) samples, Trichuris trichiura 1 (6.25%) sample, and Hookworm 1 (6.25%) sample. There were STH contamination on cabbage and lattuce in the traditional market in Jambi city.
Key word: Soil Transmitted Helminths, contamination, infection

ABSTRAK
Penularan infeksi Soil Transmited Helminths (STH) dapat terjadi melalui makanan yang terkontaminasi telur cacing. Jenis makanan yang paling sering terkontaminasi diantaranya adalah kubis dan selada. Penelitian ini bertujuan menemukan kontaminasi telur STH dan mengidentifikasi jenis telur cacing yang mengontaminasi sayur kubis dan selada di pasar tradisional Kota Jambi. Penelitian ini adalah penelitian deskriptif yang dilakukan di Laboratorium Biomedik Fakultas Kedokteran dan Ilmu Kesehatan Universitas Jambi pada bulan Juli–Agustus 2018. Sampel sayuran diambil dari tiga pasar tradisional di Kota Jambi yaitu, pasar Talang Banjar, Angso Duo dan Simpang Pulai. Sampel sayuran terdiri atas 9 kubis dan 9 selada dari setiap pasar. Sebanyak 50 gram sampel diperiksa dengan metode sedimentasi. Hasilnya ditemukan telur STH pada 16 (29,6%) sampel sayuran. Pada sayur selada jenis telur yang mengkontaminasi yaitu Ascaris lumbricoides pada 6 (37,50%) sampel, campuran Ascaris lumbricoides dan Trichuris trichiura pada 3 (18,75%) sampel, cacing tambang pada 2 (12,50%) sampel, dan Trichuris trichiura pada 1 (6,25%) sampel. Sedangkan pada sayur kubis jenis telur yang mengkontaminasi yaitu Ascaris lumbricoides pada 2 (12,50%) sampel, Trichuris trichiura pada 1 (6,25%) sampel, dan Cacing tambang pada 1 (6,25%) sampel. Terdapat kontaminasi STH pada sayur kubis dan selada di pasar tradisional kota Jambi.
Kata kunci: Soil Transmitted Helminths, kontaminasi, infeksi
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN GEJALA DERMATITIS KONTAK PADA PEMULUNG DI TPA TALANG GULO KOTA JAMBI TAHUN 2021
Authors: Sholeha Maratus , Ena Sari Rumita , Hidayati Fajrina 
Published: December 2023

The skin disease produced by the workers is 80% of dermatitis contact. Contact dermatitis can occur in various kinds of work, one is a scavengers. Preliminary studies conducted at Talang Gulo Landfill Jambi City in 2020, it was found that 7 of the 10 scavengers experienced symptoms of contact dermatitis. The purpose of this research was to determine the Factors associated with symptomps of conctact cermatitis among ccavengers at the Talang Gulo Landfill Jambi City.This was an analytic observational study using cross sectional design. The research sample was 62 respondents, sampling was done by accidental sampling. Data analysis was performed by univariate test and chi-square test (95% CI (p-value= 0.05). Based on the results of the univariate analysis showed that 67,7% of scavengers had complaints of contact dermatitis symptoms. For bivariate analysis through chi square test, it had a significant relationship with the symptoms of contact dermatitis is the age variable (pvalue=0.019), gender (pvalue=0.000), personal hygiene (pvalue=0.000) and the use of personal protective equipment (PPE) (pvalue=0.015), contact duration (pvalue0,000), and frequency of contact (pvalue=0,010). While there is no relationship between years (pvalue=0.083), education level (pvalue=0,151). There is a relationship between age, gender, personal hygiene, use of PPE, contact time, contact frequency with the incidence of contact dermatitis symptoms. There is no relationship between years of service and level of education variable to the incidence of contact dermatitis symptoms.
INOVASI PEMBELAJARAN PENGGUNAAN INSTRUMEN STROBE (Strengthening The Reporting Of Observasional Studies In Epidemiology) DAN PRISMA (Prefered Reporting Items For Systematic Reviews And Meta-Analyses) PADA MATERI AJAR JURNAL READING PROGRAM STUDI PROFESI DO
Authors: Darmawan Armaidi , Aurora Wahyu Indah Dewi , Nuriyah Nuriyah 
Published: December 2023

ABSTRAK
Pendahuluan: Dalam dunia Pendidikan kedokteran, membaca dan mencari literasi adalah satu hal yang wajib dan penting untuk dilakukan oleh mahasiswa, karena seperti diketahui bahwa bidang kedokteran adalah ilmu yang selalu berubah-ubah dan selalu update sesuai dengan perkembangan zaman. Kemampuan peserta didik dalam menelaah sebuah jurnal menjadi keharusan untuk meningkatkan kemampuan literasi. Tujuan dari penelitian ini adalah meningkatkan keahlian mahasiswa dalam membaca, memahami, menganalisis dan mengkritisi jurnal atau penelitian terdahulu menggunakan instrument STROBE dan PRISMA.
Metode: Penelitian ini adalah jenis penelitan Research and Development yaitu metode penelitian yang digunakan untuk menghasilkan produk tertentu dan menguji keefektifan produk tersebut. Subjek dalam penelitian ini adalah mahasiswa mahasiswa profesi dokter stase IKM KK, Instrument yang digunakan adalah STROBE dan PRISMA. Adapun lembar observasi mencakup kesesuaian hasil telaah dan isi jurnal, pemahaman terhadap metodologi, pemahamaan terhadap analisis data, pemahaman terhadap hasil penelitian, pemahaman terhadap konten dan diskusi jurnal dan ketepatan mengambil kesimpulan dari jurnal
Hasil: Hasil penelitian memperlihatkan bahwa kelompok mahasiswa yang menggunakan instrument STROBE dalam menelaah jurnal memiliki score 89, instrument PRISMA 87 dan istrumen lainnya score 78.
Kesimpulan: dari hasil terlihat bahwa dari 3 kelompok perlakuan kelompok yang menggunakan instrument STROBE dan PRISMA lebih baik dalam kemampuan menganalisis sebuah jurnal dibandingkan dengan instrument dibandingkan dengan kelompok yag tidak memakai kedua instrument tersebut.

Katakunci: Inovasi Pembelajaran, Journal Reading, STROBE, PRISMA
Analisis Faktor Risiko Terhadap Kejadian Hipertensi Pada Dewasa Muda Di Kota Jambi
Authors: Kendariah Andini , Quzwain Fairuz 
Published: December 2023

ABSTRAK

Latar Belakang: Salah satu kategori Penyakit Tidak Menular (PTM) adalah hipertensi. Beberapa faktor yang dapat mengakibatkan terjadinya hipertensi pada usia dewasa muda adalah riwayat keluarga, kelebihan berat badan, kebiasaan merokok , dan faktor stress.
Metode: Penelitian ini merupakan penelitian deskriptif analitik dengan metode pendekatan unmatching case-control. Jumlah sampel penelitian sebanyak 162 responden dengan 81 responden kasus dan 81 responden control. Sampel yang diambil menggunakan teknik accidental sampling.
Hasil: Analisis data menggunakan uji Chi Square dan uji spearman. Hasil penelitian didapatkan bahwa faktor yang berhubungan dengan kejadian hipertensi pada dewasa muda adalah genetic atau riwayat keluarga (p= 0,004), indeks massa tubuh (0,001) dan tingkat stress (p=0,000). Sedangkan faktor yang tidak berhubungan adalah jenis kelamin (p=0,174) dan kebiasaan merokok (p= 0,274). Dengan variabel paling dominan adalah Indeks Massa Tubuh.
Kesimpulan: Genetik atau riwayat keluarga, indeks massa tubuh dan tingkat stress berhubungan dengan kejadian hipertensi pada dewasa muda di Kota Jambi.

Kata Kunci: Faktor risiko, kejadian hipertensi, dewasa muda
Gambaran Citra Tubuh Pada Ibu Pasca Persalinan Di Kota Jambi Tahun 2022
Authors: Yomiga Fajar Fadlan , Eliezer Victor 
Published: December 2023

ABSTRAK

Latar Belakang: Seorang Ibu Pasca Persalinan akan mengalami fase transisi yang dapat menyebabkan beberapa perubahan fisik dan juga psikologis. Salah satunya adalah terjadinya perubahan berat badan dan bentuk tubuh. Perubahan tubuh yang terjadi dari pra-kehamilan dapat meningkatkan ketidakpuasan citra tubuh. Tujuan penelitian ini Untuk mengetahui Gambaran Citra Tubuh Ibu Pasca Persalinan di Kota Jambi Tahun 2022.
Metode: Jenis penelitian yang akan dilakukan adalah studi Descriptive, penelitian ini dilakukan di Puskesmas Kota Jambi. Populasi pada penelitian ini adalah seluruh ibu yanng mempunyai anak balita dan membawa anak balita ke Poli Imunisasi. 106 sampel teknik accidental sampling. Analisa data univariat disajikan dalam bentuk distribusi frekuensi, dan pengolahan data menggunakan system komputerisasi.
Hasil: Umur ibu terbanyak adalah 26-35 tahun yaitu 61 orang (57,5%) dengan Pendidikan terbanyak adalah SMA yaitu 67 orang (63,2%), jenis persalinan sama banyak yaitu pervaginam dan Sectio Caesarea yaitu 53 orang (50%), paritas terbanyak adalah multipara yaitu 54 orang (50,9%), IMT terbanyak adalah normal yaitu 59 orang (55,7%), rerata peningkatan berat badan sebelum dan sesudah persalinan adalah 7 kg dan citra tubuh setelah persalinan terbanyak tidak ada perhatian yaitu 82 orang (77,4%)..
Kesimpulan: Gambaran citra tubuh ibu pasca persalinan di Kota Jambi Tahun 2022 terbanyak adalah tidak ada perhatian

Kata Kunci: Citra Tubuh, Ibu Pasca Persalinan
Gambaran Pengetahuan, Sikap, Dan Perilaku Dalam Penggunaan Antibiotik Oleh Pasien Di Puskesmas Kebun Kopi
Authors: Gracella Michelle , Aurora Wahyu Indah Dewi , Rahmatillah Imat 
Published: December 2023

Latar Belakang: Resistensi antimikroba (AMR) adalah masalah kesehatan masyarakat global. Pengetahuan dan sikap adalah faktor kognitif sosial pada tingkat individu yang mempengaruhi dan berhubungan dengan perilaku termasuk perilaku penggunaan antibiotik.
Metode: Penelitian menggunakan mix methode dengan menggunakan kuisioner kepada pasien PKM Kebun Kopi dan wawancara kepada dokter, apoteker, dan salah satu pasien PKM Kebun Kopi. Sampling menggunakan metode Convinience Sampling dan diperoleh 32 responden. Data dianalisis secara univariat dan bivariat dengan metode Chi-square.
Hasil: Dari hasil kuisioner yang dibagikan kepada 32 responden, tingkat pengetahuan penggunaan antibiotik yang baik 31%, cukup 28% dan kurang 40%. Tingkat sikap yang baik19%, cukup 62%, dan kurang 19%. Tingkat perilaku yang baik28%, cukup 53%, dan kurang 19%. Tidak ditemukan hubungan signifikan antara pengetahuan penggunaan antibiotik terhadap sikap dan perilaku penggunaan antibiotik (p=0,330; p=0,058).
Kesimpulan: Pengetahuan pasien di PKM Kebun Kopi terkait penggunaan antibiotik masih kurang. Namun sebagian besar telah memiliki sikap dan perilaku yang cukup baik. Tidak ditemukan hubungan antara pengetahuan terhadap sikap dan perilaku pasien terkait penggunaan antibiotik.

Kata kunci: antibiotik, pengetahuan, sikap, perilaku