bluuebunny/crossref_metadata_2025_split huggingface dataset:
Husbandry conditions of spotted ratfish (Hydrolagus colliei, Chimaeriformes) in aquaria for successful embryonic development and long‐term survival of juveniles
Authors: Berio Fidji , Charron Raphaël , Dagouret Jean‐Marie , De Gasperis Florent , Éon Aurore , Meunier Emmanuel , Simonet Morrigane , Verschraegen Nathalie , Hirel Nicolas 
Published: December 2023

AbstractThe spotted ratfish Hydrolagus colliei is the most common holocephalan species exhibited in aquaria worldwide for introducing deep‐sea environments and raising awareness of their conservation. However, little is known about the biology of H. colliei. Current practices in aquaria allow long‐term survival of sexually mature H. colliei specimens; however, this species struggles to complete a reproductive cycle in captivity mostly because embryos do not reach the hatchling stage. The aquarists of Planet Ocean Montpellier (POM, France) have bred H. colliei for 15 years and recorded parameters suitable for this species' successful embryonic and post‐embryonic development. POM aquarists now regularly record egg‐laying events of H. colliei and use four tanks to incubate eggs and raise neonates, late hatchlings, early and intermediate juveniles, subadults, and sexually mature specimens. In this work we provide the first long‐term biometric data on H. colliei from the hatchling to the subadult stage. We also report the biotic and abiotic parameters sufficient to breed H. colliei in aquaria. We finally describe the methods used to facilitate individual monitoring of specimens along the ontogeny and several pathologies identified in this species, their putative causes, and the corresponding treatments. This work highlights the importance of ex situ research and points to the valuable outcomes of collaborative efforts between aquaria and academia in deciphering the biology of species whose study in the wild remains challenging.
Vision
Authors: Mourits Maarten P. 
Published: December 2023

AbstractLight beams refracted by the cornea and lens are focused on the retina. In the rods and cones, photons generate an electrical signal which is modified and sent to the occipital cortex, where a single image is created. We distinguish five aspects of vision: visual acuity, color vision, dark vision, visual field, and stereoscopic vision.
On symbology and differential equations of Feynman integrals from Schubert analysis
Authors: He Song , Jiang Xuhang , Liu Jiahao , Yang Qinglin 
Published: December 2023

Abstract
We take the first step in generalizing the so-called “Schubert analysis”, originally proposed in twistor space for four-dimensional kinematics, to the study of symbol letters and more detailed information on canonical differential equations for Feynman integral families in general dimensions with general masses. The basic idea is to work in embedding space and compute possible cross-ratios built from (Lorentz products of) maximal cut solutions for all integrals in the family. We demonstrate the power of the method using the most general one-loop integrals, as well as various two-loop planar integral families (such as sunrise, double-triangle and double-box) in general dimensions. Not only can we obtain all symbol letters as cross-ratios from maximal-cut solutions, but we also reproduce entries in the canonical differential equations satisfied by a basis of d log integrals.
Holographic weak measurement
Authors: Sun Xinyu , Jian Shao-Kai 
Published: December 2023

Abstract
In this paper, we study a holographic description of weak measurements in conformal field theories (CFTs). Weak measurements can be viewed as a soft projection that interpolates between an identity operator and a projection operator, and can induce an effective central charge distinct from the unmeasured CFT. We model the weak measurement by an interface brane, separating different geometries dual to the post-measurement state and the unmeasured CFT, respectively. In an infinite system, the weak measurement is related to ICFT via a spacetime rotation. We find that the holographic entanglement entropy with twist operators located on the defect is consistent in both calculations for ICFT and weak measurements. We additionally calculate the boundary entropy via holographic entanglement as well as partition function. In a finite system, the weak measurement can lead to a rich phase diagram: for marginal measurements the emergent brane separates two AdS geometries, while for irrelevant measurements the post-measurement geometry features an AdS spacetime and a black hole spacetime that are separated by the brane. Although the measurement is irrelevant in the later phase, the post-measurement geometry can realize a Python’s lunch. Finally, we discuss the thick brane construction for measurement and higher-dimension extensions of our model. For these general cases, our results above are still shown to be valid.
From framework to industrial implementation: the digital twin in process planning
Authors: Wagner Sarah , Gonnermann Clemens , Wegmann Marc , Listl Franz , Reinhart Gunther , Weyrich Michael 
Published: December 2023

AbstractIn today’s fast-paced market, companies are challenged to meet increasing customer demands and shorter product life cycles. To successfully respond to these demands, companies must produce a wide variety of different products. This requires the determination of necessary processes and resources for each product, which can be difficult for process engineers due to the high manual effort and expertise involved. The current state of research has not yet provided explicit definitions of the necessary knowledge and has not fully achieved complete process planning automation. To address this challenge, a digital twin is a valuable tool for automating and understanding process planning. This paper presents a digital twin concept for process planning. It automatically analyzes the product, determines production processes, and selects appropriate resources by linking information about products, resources, and processes. The effectiveness of the digital twin concept is demonstrated through verified and validated use cases, including the production of a compressor element.
Socioeconomic Disparities for Early Childhood Anthropometrics and Vocabulary and Socio-emotional Skills: Dynamic Evidence from Chilean Longitudinal Data
Authors: Behrman Jere R. , Contreras Dante , Palma Maria Isidora , Puentes Esteban 
Published: December 2023

AbstractThis paper investigates the impact of socioeconomic (SES) disparities on anthropometrics, receptive vocabulary skills, and socio-emotional skills in Chilean children 31–83 months old (n = 7744). Longitudinal data allow for the estimation of dynamic models of child growth and skill formation while adjusting for mother's schooling and cognitive ability. The results show small length differences at birth with the better-off being shorter, but these differences are reversed during the first 10 months of life, at which age SES disparities in height-for-age z scores (HAZ) favored the better-off. Disparities in receptive vocabulary skills found at 30 months continue until the child is at least 6 years old. For socio-emotional skills, we found SES disparities before 72 months, but not after. Our results indicate that—even after controlling for factors that are not usually considered in the literature, such as mother's cognitive ability and lagged skills—SES remains significantly associated with child development outcomes within a dynamic context.
A multivariate heavy-tailed integer-valued GARCH process with EM algorithm-based inference
Authors: Jang Yuhyeong , Sundararajan Raanju R. , Barreto-Souza Wagner 
Published: December 2023

AbstractA new multivariate integer-valued Generalized AutoRegressive Conditional Heteroscedastic (GARCH) process based on a multivariate Poisson generalized inverse Gaussian distribution is proposed. The estimation of parameters of the proposed multivariate heavy-tailed count time series model via maximum likelihood method is challenging since the likelihood function involves a Bessel function that depends on the multivariate counts and its dimension. As a consequence, numerical instability is often experienced in optimization procedures. To overcome this computational problem, two feasible variants of the expectation-maximization (EM) algorithm are proposed for estimating the parameters of our model under low and high-dimensional settings. These EM algorithm variants provide computational benefits and help avoid the difficult direct optimization of the likelihood function from the proposed process. Our model and proposed estimation procedures can handle multiple features such as modeling of multivariate counts, heavy-tailedness, overdispersion, accommodation of outliers, allowances for both positive and negative autocorrelations, estimation of cross/contemporaneous-correlation, and the efficient estimation of parameters from both statistical and computational points of view. Extensive Monte Carlo simulation studies are presented to assess the performance of the proposed EM algorithms. Two empirical applications of our approach are provided. The first application concerns modeling bivariate count time series data on cannabis possession-related offenses in Australia, while the second one involves modeling intraday high-frequency financial transactions data from multiple holdings in the U.S. financial market.
A life cycle perspective of startup accelerators
Authors: de Klerk Saskia , Miles Morgan P. , Bliemel Martin 
Published: December 2023

AbstractAccelerators are broadly seen as platforms that government, non-profit, and for-profit organizations use to fast-track the development of entrepreneurial and SME business capabilities. Typically, this occurs as competitive, time-constrained, cohort-centered, authentic learning experiences supported by mentoring and access to the local entrepreneurial ecosystem, management development programs, and financial resources. Interest in how the ventures in the development programs evolve and contribute to the entrepreneurial ecosystem is increasing (Cantner et al. in Small Business Economics, 57, 407–423, 2021), but how the accelerators evolve has yet to be adequately researched. To better understand how accelerators evolve, we adapt Churchill and Lewis (Harvard Business Review, 61(3), 30–50, 1983) conceptual framework of the stages of small business development. This study investigated the life cycle of Australian accelerators from 2013 to 2020. The accelerators ranged from short-term “pop-up” programs to permanent programs. We found through a series of four selected exemplar case studies that these accelerators exhibited a similar four-stage life cycle to their participants, including (1) gestation, (2) survival, (3) viability, and (4) decline or renewal. We also found that external support was a critical issue that determined viability. Our findings support the development of accelerator management to be more agile, resilient, and entrepreneurial, which can confront those adopting a more standardized franchise model. In addition, we adapt Kohler (Business Horizons, 59(3), 347–357, 2016) work on corporate accelerators into an inclusive framework for all forms of accelerators, including considering their geographic context or Place, the actors involved with the accelerator or its People, the accelerator’s value Proposition to participants, the accelerator’s Processes and most fundamentally, its Purpose that will contribute to the entrepreneurial ecosystem practice and literature. This research provides practical considerations on positioning, suitable business models, and maximized operations.
The population structure of the Fusarium brachygibbosum species complex in the grassland biome of South Africa
Authors: Dhlamini Lerato , Jacobs Adriaana , van der Merwe Nicolaas A. , Summerell Brett , Venter Eduard 
Published: December 2023

AbstractFusarium brachygibbosum Padwick is a phytopathogen with a widespread distribution, infecting various host plants. In South Africa, there is a limited number of studies on the genetic diversity of fusaria, particularly in undisturbed soils. In the current study, the genetic diversity of F. brachygibbosum was investigated using inter-simple sequence repeat (ISSR) and mating type genes. The F. brachygibbosum isolates were collected from four different geographic regions within the grassland biome of South Africa. A total of ten ISSR primers produced 64 distinct and reproducible amplicons, with 100% polymorphism. The ISSR markers revealed high levels of intraspecific variation, which is depicted by various genetic diversity indexes. In the analysis of mating type genes, the MAT1-1-2 gene was found among the four populations, but the MAT1-2-1 gene was only present in the population from the Groenkloof Nature Reserve. The data from this study will contribute substantially to knowledge of grassland fusaria of South Africa and their population structure in the grassland biome.
Diagnostic testing and antibiotic utilization among inpatients evaluated for coronavirus disease 2019 (COVID-19) pneumonia
Authors: Wimmer Megan R. , Griffin Meggie , Peterson-Weber Alex , Schulz Lucas T. , Hamel Ashlee G. , Schwei Rebecca J. , Fong Karen , Burgess Donna R. , Brett Meghan , Hale Cory M. , Holubar Marisa , Jain Rupali , Larry Rachel , Spivak Emily S. , Newland Helen , Njoku Jessica , Postelnick Michael , Walraven Carla , Pulia Michael S. 
Published: December 2023

AbstractWe evaluated diagnostic test and antibiotic utilization among 252 patients from 11 US hospitals who were evaluated for coronavirus disease 2019 (COVID-19) pneumonia during the severe acute respiratory coronavirus virus 2 (SARS-CoV-2) omicron variant pandemic wave. In our cohort, antibiotic use remained high (62%) among SARS-CoV-2–positive patients and even higher among those who underwent procalcitonin testing (68%).
The genus Usnea (Parmeliaceae, Ascomycota) in the southern Philippines: a first phylogenetic approach
Authors: Gerlach Alice , Clerc Philippe , Lücking Robert , Moncada Bibiana , Nobleza Joevina Caballero , Ohmura Yoshihito , Dal Forno Manuela 
Published: December 2023

AbstractA first integrative survey of the genus Usnea in the southern Philippines, taking into account morphological, anatomical, chemical and molecular characters, resulted in the recognition of 20 taxa, including three species new to science: Usnea angulata Ach., U. baileyi (Stirt.) Zahlbr., U. bismolliuscula Zahlbr., U. brasiliensis (Zahlbr.) Motyka, U. confusa Asah., U. croceorubescens Stirt., U. dasaea Stirt., U. himalayana C. Bab., U. krogiana P. Clerc, U. longissima Ach., U. nidifica Taylor, U. norsticornuta A. Gerlach & P. Clerc sp. nov. (characterized by a moderately thick cortex and by the presence of norstictic acid), U. paleograndisora A. Gerlach & P. Clerc sp. nov. (characterized by an orange subcortical pigmentation in the medulla, with enlarging soralia and a moderately thick and shiny cortex), U. pectinata Taylor, U. pygmoidea (Asahina) Y. Ohmura, U. rubicunda Stirt., U. rubrotincta (Stirt.) Zahlbr., U. spinulifera (Vain.) Motyka, U. subscabrosa Motyka and U. yoshihitoi P. Clerc & A. Gerlach sp. nov. (characterized by a lax medulla with non-conglutinated hyphae). Usnea krogiana is a new record for Asia; Usnea brasiliensis, Usnea confusa and U. croceorubescens are new records for the Philippines. This is the first phylogenetic study to include DNA sequences of Usnea from the Philippines. Molecular data from the ITS rDNA (76 newly generated sequences) are presented for most taxa except for U. himalayana, U. longissima and U. subscabrosa. At least six further taxa remain unidentified, awaiting the collection of additional specimens.
New insight in massive cerebral infarction predictions after anterior circulation occlusion
Authors: Chen Jingshu , Zou Mingyu , Zhang Nan , Qi Shouliang , Yang Benqiang , Zhang Libo , Shi Lin , Duan Yang 
Published: December 2023

AbstractTo predict massive cerebral infarction (MCI) occurrence after anterior circulation occlusion (ACO) by cASPECTS-CTA-CS (combined ASPECTS and CTA-CS). Of 185 cerebral infarction patients with the ACO, their collateral circulation scores from CT angiography (CTA) images in two groups (MCI and non-MCI) were evaluated using Alberta Stroke Program Early CT Score (ASPECTS) and CT angiography collateral score (CTA-CS) approaches. The cASPECTS-CTA-CS was validated internally using the bootstrap sampling method with 1000 bootstrap repetitions and compared to CTA-CS. Receiver-operating characteristic curve (ROC), clinical impact curve (CIC), and decision curve analysis (DCA) strategies were used to assess the clinical practicality and predictability of both approaches (cASPECTS-CTA-CS and CTA-CS). Using net reclassification improvement (NRI) and integrated discrimination improvement (IDI) analyses, discrimination levels of the cASPECTS-CTA-CS were compared with CTA-CS. Classification and regression tree (CART) analyses was conducted to identify the best predictive values and identify subgroup of MCI. The discrimination ability of collateral circulation evaluation score using the cASPECTS-CTA-CS [AUC: 0.918, 95% confidence interval (CI): 0.869–0.967, P < 0.01; NRI: 0.200, 95% CI: −0.104 to 0.505, P = 0.197; and IDI: 0.107, 95% CI: 0.035–0.178, P = 0.004] was better than CTA-CS alone (AUC: 0.885, 95% CI: 0.833–0.937, P < 0.01). DCA indicated the net benefits of the cASPECTS-CTA-CS approach was higher than CTA-CS alone when the threshold probability range over 20%. CIC analyses showed that the number of high risks and true positives were in agreement when the threshold probability > 80%. Less than 23 of cASPECTS-CTA-CS by CART was important factor in determining MCI occurrence, and ASPECTS < 7 was followed factor. The cASPECTS-CTA-CS approach cumulatively predicted MCI after ACO.
Efficacy of nafamostat mesylate in the prevention of pancreatitis after endoscopic retrograde cholangiopancreatography: a systematic review and meta-analysis of randomized controlled trials
Authors: Narumi Kazuaki , Okada Tomoki , Lin Yingsong , Kikuchi Shogo 
Published: December 2023

AbstractWe conducted a systematic review and meta-analysis to evaluate the effect of nafamostat on the prevention of post-endoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP). PubMed, Web of Science, and Ichushi Web were searched for randomized controlled trials (RCTs) using nafamostat to prevent PEP. In subgroup analyses, we studied the preventive effects of nafamostat according to the severity of PEP, risk category, and dose. A random-effects model was adopted; heterogeneity between studies was examined using the chi-squared test and I2 statistics. This analysis uses the PRISMA statement as general guidance. 9 RCTs involving 3321 patients were included. The risk of PEP was lower in the nafamostat group than in the control group [4.4% vs. 8.3%, risk ratio (RR): 0.50, 95% confidence interval (CI): 0.36–0.68]. In subgroup analyses, the protective effects were evident in low-risk patients for PEP before ERCP (RR: 0.34, 95% CI: 0.21–0.55). The association between PEP and nafamostat was significant only in patients who developed mild PEP (RR: 0.49; 95% CI: 0.36–0.69). The benefits were independent of the dose. The prophylactic use of nafamostat resulted in a lower risk of PEP. The subgroup analyses suggested uncertain benefits for severe PEP or high-risk patients for PEP. This warrants further investigation through additional RCTs.
NICE-FF: A non-empirical, intermolecular, consistent, and extensible force field for nucleic acids and beyond
Authors: Demir Gözde İniş , Tekin Adem 
Published: December 2023

A new non-empirical ab initio intermolecular force field (NICE-FF in buffered 14-7 potential form) has been developed for nucleic acids and beyond based on the dimer interaction energies (IEs) calculated at the spin component scaled-MI-second order Møller–Plesset perturbation theory. A fully automatic framework has been implemented for this purpose, capable of generating well-polished computational grids, performing the necessary ab initio calculations, conducting machine learning (ML) assisted force field (FF) parametrization, and extending existing FF parameters by incorporating new atom types. For the ML-assisted parametrization of NICE-FF, interaction energies of ∼18 000 dimer geometries (with IE &lt; 0) were used, and the best fit gave a mean square deviation of about 0.46 kcal/mol. During this parametrization, atom types apparent in four deoxyribonucleic acid (DNA) bases have been first trained using the generated DNA base datasets. Both uracil and hypoxanthine, which contain the same atom types found in DNA bases, have been considered as test molecules. Three new atom types have been added to the DNA atom types by using IE datasets of both pyrazinamide and 9-methylhypoxanthine. Finally, the last test molecule, theophylline, has been selected, which contains already-fitted atom-type parameters. The performance of NICE-FF has been investigated on the S22 dataset, and it has been found that NICE-FF outperforms the well-known FFs by generating the most consistent IEs with the high-level ab initio ones. Moreover, NICE-FF has been integrated into our in-house developed crystal structure prediction (CSP) tool [called FFCASP (Fast and Flexible CrystAl Structure Predictor)], aiming to find the experimental crystal structures of all considered molecules. CSPs, which were performed up to 4 formula units (Z), resulted in NICE-FF being able to locate almost all the known experimental crystal structures with sufficiently low RMSD20 values to provide good starting points for density functional theory optimizations.
ZSCAN4-binding motif—TGCACAC is conserved and enriched in CA/TG microsatellites in both mouse and human genomes
Authors: Akiyama Tomohiko , Ishiguro Kei-ichiro , Chikazawa Nana , Ko Shigeru B H , Yukawa Masashi , Ko Minoru S H 
Published: December 2023

Abstract
The Zinc finger and SCAN domain containing 4 (ZSCAN4) protein, expressed transiently in pluripotent stem cells, gametes, and early embryos, extends telomeres, enhances genome stability, and improves karyotypes in mouse embryonic stem (mES) cells. To gain insights into the mechanism of ZSCAN4 function, we identified genome-wide binding sites of endogenous ZSCAN4 protein using ChIP-seq technology in mouse and human ES cells, where the expression of endogenous ZSCAN4 was induced by treating cells with retinoic acids or by overexpressing DUX4. We revealed that both mouse and human ZSCAN4 bind to the TGCACAC motif located in CA/TG microsatellite repeats, which are known to form unstable left-handed duplexes called Z-DNA that can induce double-strand DNA breaks and mutations. These ZSCAN4 binding sites are mostly located in intergenic and intronic regions of the genomes. By generating ZSCAN4 knockout in human ES cells, we showed that ZSCAN4 does not seem to be involved in transcriptional regulation. We also found that ectopic expression of mouse ZSCAN4 enhances the suppression of chromatin at ZSCAN4-binding sites. These results together suggest that some of the ZSCAN4 functions are mediated by binding to the error-prone regions in mouse and human genomes.