bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variables asociadas al regreso a clases presenciales, después de la emergencia sanitaria
Authors: Andraca Sánchez Ciro , González González Justiniano , Muñoz García Alejandra Hitahii , Mendoza Mojica Manuel , Bueno Domínguez Paulino 
Published: November 2023

El objetivo del estudio fue identificar las variables asociadas en la transición de las clases virtuales a las presenciales, durante la primera semana del regreso a las aulas, después de la emergencia sanitaria por la COVID-19. En el estudio transversal, basado en el enfoque descriptivo-correlacional, se analizaron variables socioeconómicas, socioemocionales y actitudinales, en estudiantes de la preparatoria No. 9 de la Universidad Autónoma de Guerrero, México. Participaron 58 alumnos y 86 alumnas. Se utilizaron las pruebas de odds ratio (OR) y chi-cuadrado, a partir de la utilización del software SPSS 25, encontrándose, con mayor significancia, la baja escolaridad de los padres (p=,000), compartir celular durante las clases virtuales (p=,000), problemas económicos familiares (p=,000), deficiente señal de internet (p=,001), tener un trabajo remunerado (p=,002), el jefe de familia no tenía un salario fijo (p=,012), y vivir fuera de la ciudad sede de la escuela (p=,044). Con respecto al sexo, se analizó la diferenciación porcentual de las variables socioemocionales: malhumor, ansiedad, aburrimiento, intranquilidad, cansancio y tristeza. Asimismo, se realizó el análisis de varianza (ANOVA) sobre la actitud estudiantil (1. muy de acuerdo o de acuerdo; 2. ni de acuerdo, ni en desacuerdo, y 3. en desacuerdo y muy en desacuerdo) frente a los efectos de la pandemia, encontrándose variaciones entre los valores de los grupos 1 y 3, respecto a las opiniones: hombres y mujeres deben compartir responsabilidades; priorizar el apoyo a la mujer para seguir estudiando, y cuando un familiar se enferma, es preferible que sea cuidado por la mujer, situación similar a lo reportado por González y Cuenca (2020), donde las mujeres fueron más propensas a la realización de tareas del hogar. Se requieren nuevas investigaciones sobre resiliencia, después de haber regresado a las clases presenciales.
The Association of Family Characteristics with Dietary Diversity among Adolescent Girls in Denpasar City, Bali, Indonesia
Authors: Utami Ni Wayan Arya , Ani Luh Seri 
Published: November 2023

Background: The three main nutritional problems in adolescent girls are chronic energy deficiency, obesity, and anemia. These problems are associated with food quality or dietary diversity, often influenced by family characteristics.
Objectives: This study aimed to determine the association of dietary diversity among adolescent girls in Denpasar City with family characteristics, such as parents' occupation, education and income, type and size of family, government social programs, and food security.
Methods: This cross-sectional study was conducted involving 516 adolescent girls selected through a multistage sampling. The first stage involved the selection of 12 villages in 4 sub-districts, and the second involved using simple random sampling to select respondents from each village. Data were obtained using the Minimum Dietary Diversity for Women questionnaire, and Multiple logistic regression was applied to identify the determinant of dietary diversity.
Results: The result showed a mean score of 6.7 (SD±1.7) with a maximum of 8.4, and the proportion of inadequate dietary diversity was 11.4%. Based on a bivariable test, six variables were found to be significantly associated with dietary diversity among adolescent girls. After including these variables in a multiple logistic regression model, it was observed that family size (AOR=6.986; 95% CI: 2.718 -17.957; p-value=0.000), mother's education (AOR =1.904; 95% CI: 1.029-3.525; p-value=0.04), and household income (AOR=0.422; 95% CI: 0.227-0.784; p-value=0.006) were significantly associated with dietary diversity.
Conclusions: In conclusion, family characteristics, such as having a family size of five or more, a lower level of mother’s education, and household monthly income below the district minimum wage, were significantly associated with inadequate dietary diversity. This condition required intervention in the form of promoting food diversification at the family level.
The Effectiveness of Smartphone-Based Nutrition Education Intervention in Successful Practice of Exclusively Breastfeeding: A Meta-Analysis
Authors: Pratiwi Rachmahnia , Atmaka Dominikus Raditya , Sutoyo Deandra Ardya Regitasari , Mahmudiono Trias 
Published: November 2023

Background: Exclusive breastfeeding is the cornerstone of infant health and one of the 2030 Sustainable Development Goals (SDGs). The advancement of information technology can be used to promote health, and providing information through messages on smartphone applications can improve breastfeeding awareness and adherence.
Objectives: To determine which social media platforms effectively promote exclusive breastfeeding through nutrition education interventions.
Methods: This study employed a meta-analysis method. The terms “breastfeeding,” “social media,” and “smartphone” were used to search for articles in multiple electronic journals, such as Scopus, PubMed, ScienceDirect, and Google Scholar. Articles that provide an intervention using smartphone media for groups of expectant mothers who wish to breastfeed their babies and mothers who have ceased breastfeeding and want to resume were selected. Forest plot analysis was performed using the STATA 12.
Results: From 2018 to 2021, seven articles were obtained, with research conducted in the United States, India, Indonesia, Israel, and Brazil. The study’s findings revealed that a nutritional education intervention using Smartphones led to an average success rate of exclusive breastfeeding between the intervention group and the control group of 1.23 (7 studies), 95% CI (1.08 - 1.39); P = 0.000; and I2 = 97.1%.
Conclusions: Intervention using smartphones by sending short messages daily and counselling by telephone every week can increase mothers’ knowledge and ability to provide exclusive breastfeeding to their infants. An intervention using smartphones to transmit daily text messages and weekly telephone counselling could enhance mothers’ knowledge and ability to breastfeed their children exclusively.
Micropore Structure Characteristics and Recoverability Evaluation of Typical Shale Oil Reservoirs
Authors: Yao Lanlan , Yang Zhengming , Li Haibo , Du Meng , Zhou Tiyao , Zhang Yapu , Huang Qianhui , Chen Xinliang , Wang Ning 
Published: November 2023

Abstract
In view of the weak research on the availability of typical shale oil reservoirs from the perspective of development, this study introduced a two-dimensional nuclear magnetic resonance (NMR) evaluation method on the basis of the previous one-dimensional NMR combined with centrifugal physical simulation experiments. Not only the production characteristics of typical shale oil reservoirs were studied but also the microscopic production laws of different occurrence states were studied. The results show that the pore distribution of Jilin shale is more concentrated than that of Qinghai shale. The oil of the two blocks mainly occurs in 0.01–10 ms pores, and the occurrence ratio of Jilin shale in the pores is higher, which is more than 90%. The oil production of the two blocks is mainly dominated by 0.01–10 ms pores, and the utilization efficiency contribution of these pores in Jilin shale is higher, accounting for about 80%. The utilization efficiency (UE) increases logarithmically with centrifugal force, and the growth rate of Jilin shale is greater than that of Qinghai shale. The proportion of free oil in Jilin block is less than that in Qinghai block. The shale oil in the two blocks is both at 15% final UE, and the UE of free oil in Jilin shale is about 9% and that of Qinghai shale is about 12%. The recoverability of Jilin shale is lower than that of Qinghai shale.
The Effect of Knowledge Brokering on Nurses' Empathy with Patients Receiving Cardiac Care: An Experimental Study
Authors: Galehdarifard Atefeh , Khademi Mojgan , Gholami Mohammad , Radfar Moloud , Ebrahimzadeh Farzad , Imani-Nasab Mohammad-Hasan 
Published: November 2023

Abstract

Background
Previous reports have suggested a relationship between empathetic behaviors and a reduction in cardiovascular events. However, evidence has also revealed a lack of empathy among nurses. Therefore, interventions are necessary to improve empathy among cardiac nurses.
Aim
To determine the effect of knowledge brokering on nurses' empathy with patients receiving cardiac care.
Methods
This is an experimental study conducted on a total of 100 cardiac nurses. Participants were assigned to two groups of control and intervention using stratified random allocation. In the intervention group, knowledge brokering was performed using Dobbin's seven-stage method. Data were collected using Empathy Construct Rating Scale (ECRS) With the overall score ranges from +252 to -252. Then, data were analyzed using SPSS version 21. The significance level was considered < .05.
Results
The mean empathy change score (MECS) ± standard deviation was 22.90 ± 50.93 in the intervention group (p = .003) and 7.10 ± 60.20 in the control group (p = .408). The MECS between the study groups was compared based on the baseline empathy score (BES) (<100, ≥100). This comparison revealed that in nurses with BES ≥100, the adjusted MECS in the intervention group was significantly higher than the control group (11.44 units versus -15.42 units).
Conclusion(s)
The findings indicate that the effectiveness of knowledge brokering depends on the BES of nurses. The utilization of this intervention can enhance empathetic behaviors in cardiac nurses with a BES ≥100. This empirical study contributes to a better understanding of knowledge brokering.
New record of larval-pupal endoparasitoid Exorista deligata parasitising Indian Tea looper Hyposidra talaca from India
Authors: Sharma Pooja V. , Das Tamal , Mukherjee Susmita , Pathan Ejaj K. , Rahman Azizur , Gathalkar Ganesh B. 
Published: November 2023

Abstract
This is the first record of Exorista deligata (Pandellé, 1896) (Diptera: Tachinidae) as a parasitoid of Hyposidra talaca (Walker, 1860) (Lepidoptera: Geometridae) from India. H. talaca is a major and new emerging defoliator of the Tea plant Camellia sinensis (L) Kuntze (Theaceae). It completes multiple generations per year without diapause on C. sinensis, resulting in heavy crop loss. The field-collected larvae/pupa of H. talaca were checked for parasitoid infestations and reared until either the host or parasitoid emerged. The parasitoid was identified as E. deligata with morphological characteristics and confirmed by the mitochondrial cytochrome oxidase subunit-I (COX-CO1) gene sequencing technique. The parasitoid is infrequent with unexplored parasitic biology. It parasitises the larva and completes its lifecycle inside the developing H. talaca by entirely devouring the host. The mean percent parasitisation caused by E. deligata studied herein was 25.4% (range 5.88%-57.69%). Based on its parasitisation ability, we suggest the species could be a potential biological control agent to address the damage mitigation caused by the tea looper pest, H. talaca.
Values of LncRNA SNHG14 in The Differential Diagnosis and Prognosis Evaluation of Acute Ischemic Stroke
Authors: Lu Hongxiang , Zhang Yuezhan 
Published: November 2023

Abstract

The long non-coding RNA (LncRNA) SNHG14 has been investigated for its potential in acute ischemic stroke (AIS) and transient ischemic attack (TIA) diagnosis. 32 healthy people, 85 patients with AIS, and 40 patients with TIA had their blood tested to determine SNHG14 mRNA transcript levels using quantitative real-time polymerase chain reaction. (qRT-PCR). A stroke's severity was measured using the Stroke Severity Scale developed by the National Institutes of Health. (NIHSS). After 30 days, individuals with AIS were evaluated for progress using a modified Rankin Scale. (mRS).There was no significant difference in SNHG14 LncRNA levels between TIA patients and Controls, despite the huge rise in AIS incidence. (p > 0.05). (all p 0.001). Compared to those who did well on the AIS test, those who performed poorly had substantially greater levels of SNHG14 LncRNA. (mRS 0–1 points). (mRS 0–2). LncRNA SNHG14 had an AUC of 0.714 (80%, 61.18%) when used to identify AIS in TIA patients, and a comparable finding was seen when predicting a poor 30-day prognosis of AIS (73%, 66.67%). There are also graphical representations of the findings. Improvements in NIHSS and mRS scores were associated with increases in SNHG14 LncRNA mRNA levels in individuals diagnosed with AIS. It is critical that we focus entirely on this decision. (all p 0.05).Analysis of the long non-coding RNA known as SNHG14 in the patient's blood can be used to diagnose AIS, rule out TIA, forecast the intensity of the disease, and evaluate the prognosis. You can accomplish everything on that list simultaneously.
The Distance to the Stars
Authors: Siebenmorgen Ralf , Chini Rolf 
Published: November 2023

Abstract
The vastness of a clear night sky evokes for most people curiosity about the distance to the stars. There are two primary methods for estimating stellar distances – parallax and luminosity. In this study, we present a new analysis revealing a noteworthy discrepancy between these two methods. Due to the accuracy of GAIA, parallaxes can directly be converted into distances. In contrast, luminosity distances require – apart from the determination of apparent and absolute brightness of a star – the reddening value that allows a correction for interstellar extinction. Using 47 stars with non-peculiar reddening curves from the high-quality sample1 we find here that the luminosity distance overestimates the parallactic distance for most (79%) of these stars. This puzzling discrepancy can only be removed when incorporating a new population of large dust grains – so-called dark dust – with our model2 that respects contemporary constraints of the interstellar dust3 and is updated to scope for the first time with the absolute reddening. The model provides a visual extinction which unifies the conflicting distances. Another far-reaching consequence of the flat absorption and scattering properties of dark dust is that it broadens the light curves4 of SNIa, which serve as a measure of the quantity of dark energy5.
Retifanlimab and the arginase inhibitor CB-1158 show low activity in microsatellite-stable colorectal cancer patient-derived organoids co-cultured with tumor-infiltrating lymphocytes
Authors: Bayo Cristina , Marin Silvia , Madurga Sergio , Lahoz Sara , Archilla Ivan , Bravo Raquel , Cuatrecasas Miriam , Gines Angels , Hernandez Claudia , de Lacy Borja , Oliveres Helena , Rojas Mariam , Tarrado-Castellarnau Mariam , Valverde Silvia , Mas Francesc , Camps Jordi , Postigo Antonio , Benítez-Ribas Daniel , Cascante Marta , Maurel Joan 
Published: November 2023

Abstract
Background
Cancer immunotherapies show low activity in metastatic microsatellite-stable (MSS) colorectal cancer (CCR) patients. Arginase 1 inhibitors have shown activity in pre-clinical models associated with PD-1 inhibitors.
Methods
We established a platform with co-cultures of metastatic MSS CCR patient-derived organoids (PDOs) and expanded autologous tumor-infiltrating lymphocytes to evaluate the efficacy of retifanlimab (PD-1 inhibitor), CB-1158 (arginase inhibitor), and their combination. CB-1158, retifanlimab, and CB-1158 + retifanlimab were tested using two PDOs representative of the IMMETCOLS IMC3 signature.
Results
Increased T-cell PDOs recognition was observed in co-cultures versus T cells alone. CB-1158, retifanlimab and CB- 1158 plus retifanlimab failed to increase T-cell PDOs recognition and T-cell cytotoxic effects. CB-1158 inhibited arginase, but the impaired synthesis of endogenous ornithine, through arginase, decreased ornithine release into the co-culture medium and increased glutamine, histidine, and putrescine consumption as compensation to guarantee ornithine and polyamines synthesis.
Conclusion
These results demonstrate the lack of meaningful activity of both monotherapy and combination therapy in PDO and autologous tumor-infiltrating lymphocyte preclinical models and suggest modest clinical activity in metastatic CCR MSS, at least in tumors meeting IMC3 metabolic characteristics.
Comparative transcriptional analysis identifies genes associated with the attenuation of Theileria parva infected cells after long-term in vitro culture
Authors: Heijden Elisabeth van der , Lefevre Lucas , Gossner Anton , Tzelos Thomas , Connelley Timothy , Hassan Musa 
Published: November 2023

Abstract
Autologous administration of attenuated Theileria parva-infected cells induces immunity to T. parva in cattle. The mechanism of attenuation, however, is largely unknown. Here, we used RNA sequencing of pathogenic and attenuated T. parva-infected T-cells to elucidate the transcriptional changes underpinning attenuation. We observed differential expression of several host genes, including TRAIL, PD-1, TGF-β and granzymes that are known to regulate inflammation and proliferation of infected cells. Importantly, many genes linked with the attenuation of the related T. annulata-infected cells were not dysregulated in this study. Furthermore, known T. parva antigens were not dysregulated in attenuated relative to pathogenic cells, indicating that attenuation is not due to enhanced immunogenicity. Overall this study suggests that attenuation is driven by a decrease in proliferation and restoration of the inflammatory profile of T. parva-infected cells. Additionally, it provides a foundation for future mechanistic studies of the attenuation phenotype in Theileria-infected cells.
Integrating brainstem and cortical functional architectures
Authors: Misic Bratislav , Hansen Justine , Cauzzo Simone , Singh Kavita , Garcia-Gomar Maria Guadalupe , Shine James , Bianciardi Marta 
Published: November 2023

Abstract

The brainstem is a fundamental component of the central nervous system yet it is typically excluded from in vivo human brain mapping efforts, precluding a complete understanding of how the brainstem influences cortical function. Here we use high-resolution 7 Tesla fMRI to derive a functional connectome encompassing cortex as well as 58 brainstem nuclei spanning the midbrain, pons and medulla. We identify a compact set of integrative hubs in the brainstem with widespread connectivity with cerebral cortex. Patterns of connectivity between brainstem and cerebral cortex manifest as multiple emergent phenomena including neurophysiological oscillatory rhythms, patterns of cognitive functional specialization, and the unimodal-transmodal functional hierarchy. This persistent alignment between cortical functional topographies and brainstem nuclei is shaped by the spatial arrangement of multiple neurotransmitter receptors and transporters. We replicate all findings using 3 Tesla data from the same participants. Collectively, we find that multiple organizational features of cortical activity can be traced back to the brainstem.
Heritable changes in chromatin contacts linked to transgenerational obesity
Authors: Blumberg Bruce , Chang Richard Cheng-An , Egusquiza Riann , Amato Angélica , Li Zhuorui , Joloya Erika , Wheeler Hailey , Nguyen Angela , Shioda Keiko , Odajima Junko , Lawrence Michael , Shioda Toshi 
Published: November 2023

Abstract
Burgeoning evidence demonstrates that effects of environmental exposures can be transmitted to subsequent generations through the germline without DNA mutations1,2. This phenomenon remains controversial because underlying mechanisms have not been identified. Therefore, understanding how effects of environmental exposures are transmitted to unexposed generations without DNA mutations is a fundamental unanswered question in biology. Here, we used an established murine model of male-specific transgenerational obesity to show that exposure to the obesogen tributyltin (TBT) elicited heritable changes in chromatin interactions (CIs) in primordial germ cells (PGCs). New CIs were formed within the Ide gene encoding Insulin Degrading Enzyme in the directly exposed PGCs, then stably maintained in PGCs of the subsequent (unexposed) two generations. Concomitantly, Ide mRNA expression was decreased in livers of male descendants from the exposed dams. These males were hyperinsulinemic and hyperglycemic, phenocopying Ide-deficient mice that are predisposed to adult-onset, diet-induced obesity. Creation of new CIs in PGCs, suppression of hepatic Ide mRNA, increased fat mass, hyperinsulinemia and hyperglycemia were male-specific. Our results provide a plausible molecular mechanism underlying transmission of the transgenerational predisposition to obesity caused by gestational exposure to an environmental obesogen. They also provide an entry point for future studies aimed at understanding how environmental exposures alter chromatin structure to influence physiology across multiple generations in mammals.
ASAP: an automatic sequential assignment program for congested multidimensional solid state NMR spectra
Authors: Chen Bo 
Published: November 2023

Abstract

Accurate signal assignments can be challenging for congested solid-state NMR (ssNMR) spectra. We describe an automatic sequential assignment program (ASAP) to partially overcome this challenge. ASAP takes three input files: the residue type assignments (RTAs) determined from the better-resolved NCACX spectrum, the full peak list of the NCOCX spectrum, and the protein sequence. It integrates our auto-residue type assignment strategy (ARTIST) with the Monte Carlo simulated annealing (MCSA) algorithm to overcome the hurdle for accurate signal assignments caused by incomplete side-chain resonances and spectral congestion. Combined, ASAP demonstrates robust performance and reduces the time of signal assignments of large proteins (> 200 residues) from years to days.
Laser-printed 3D full-thickness skin equivalent morphology and metabolism monitoring by dual-mode OCT/Fluorescence system
Authors: Sokolovski Sergei , Khalid Arooj , Dremin Viktor , El-Tamer Ayman , Surmina Maria , Lancelot Celine , Rafailov Edik 
Published: November 2023

Abstract
The 3D architecture of native human skin is a crucial requirement in investigating the skin in health and pathologies, wound healing, and testing of skin cosmetic and care product safety and personalized skin disease treatments. In this research, we used human skin cell lines to build full-thickness skin equivalents (FSE). Tissue regenerative medicine is based on tissue engineering and so far, FSE is well known approach to developing healthy and pathological skin models. Here we architected 3D printed high-resolution scaffolds for the growth and maturation of the FSEs also developed and validated custom-built combined fluorescence spectroscopy (FS) and optical coherence tomography (OCT) imaging system for indestructible assessing metabolism and morphology of developed human FSEs on 3D printed scaffolds. This system demonstrated high sensitivity in detecting fluorescence from nicotinamide adenine dinucleotide (NADH) and riboflavin 5’-adenosine diphosphate (FAD) in solutions and cell suspensions, and high-resolution imaging of FSE morphology. Thus, our developed multimodal optical system can be used in the future for the assessment of metabolism, maturation, and viability of 3D models of biological tissues in time-course development.