bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nazal Valv ve Tip Stabilitesini Korumak Amacıyla Modifiye Sliding Alar Kartilaj Tekniği Uygulanan Hastaların Retrospektif Analizi
Authors: ÜNVERDİ Ömer Faruk , YÜCEL Sercan 
Published: October 2023

GİRİŞ ve AMAÇ: Rinoplastide, internal nazal valv ve eksternal nazal valv stabilitelerinin sağlanması hem görsel hem de fonksiyonel sonuçları doğrudan etkilemektedir. Scroll ligaman kompleksinin bütünlüğü korunarak hazırlanan scroll ligaman kompleksi destekli alar kartilaj flebi internal ve eksternal valv stabilitesinin korunmasında önemli bir görev üstlenmektedir.
YÖNTEM ve GEREÇLER: Nazal şekil bozukluğu nedeniyle opere edilen 25 primer rinoplasti hastası çalışmaya dahil edildi. Nazal flep, scroll ligaman kompleksinin horizontal ve vertikal lifleri tamamen korunarak kaldırıldı. Tip plasti aşamasında alt lateral kartilaj, caudalde 5 mm lik segment korunacak şekilde caudal ve sefalik iki parçaya ayırıldı. Sefalik parça scroll ligaman kompleksi ile bütünlüğü bozulmadan flep olarak caudal parçanın altında hazırlanan cepe yerleştirildi. BULGULAR: Çalışmaya katılan hastaların 19’ u Kadın 6’sı Erkek idi. Hastaların yaş ortalaması 29,6 yıl idi. Takip süresi 14,5 ay idi. Hastaların tümü nefes alıp vermede belirgin iyileşme olduğunubildirdi. Görünümün 24 hastayı memnun ettiği 1 hastayı ise memnun etmediği sözel olarak öğrenildi. Kıkırdakların dışarıdan görünürlüğünde artma veya palpe edilmesi gibi bir komplikasyon gözlenmedi. Hastaların ameliyat sonrası muayenelerinde, internal veya eksternal nazal valv yetmezliği bulguları gözlenmedi.
TARTIŞMA ve SONUÇ: Scroll ligaman kompleksi vertikal ve longitudal liflerden oluşmaktadır. Kompleksin fonksiyonunu yerine getirebilmesi amacıyla bütünlüğünün korunması veya bütünlüğü bozulmuş olgularda tekrar onarılması gerekmektedir. Skroll ligament destekli alar kartilaj flebi, internal ve eksternal nazal valv stabilitesini sağlayan ve scroll ligaman kompleksini bir bütün olarak koruyan bir tekniktir.
Periarticular Injection of Ranawat Suspension in Combination with Tranexamic Acid Reduces Bleeding and Postoperative Pain in Total Knee Arthroplasty
Authors: MORALAR Ülker , PAMUK Çağdaş 
Published: October 2023

Objective: The benefits of periarticular injections of local anesthetic agents or tranexamic acid have been previously evaluated in terms of their effects on postoperative pain in a number of orthopedic studies. However, data is lacking on the efficacy of local anesthetic and tranexamic acid combinations that may be used for this purpose. We aimed to investigate the effects of periarticular injection of both tranexamic acid and Ranawat suspension on postoperative pain and bleeding in patients undergoing total knee arthroplasty.
Methods: A total of 124 patients who underwent total knee arthroplasty were consecutively enrolled in this study. Patients were divided into two groups: those receiving the periarticular injection of a cocktail containing the combination of Ranawat suspension and Tranexamic acid and those receiving no injections. Postoperative pain, postoperative tramadol requirement and blood loss were compared between groups.
Results: Hemoglobin and hematocrit levels were significantly higher at third day postoperatively in recipients of periarticular Ranawat suspension and tranexamic acid combination (p=0.044 and p=0.047, respectively). In addition, the amount of drainage blood loss (p
DETERMINATION OF THE EFFECT OF RUTIN ON EPITHHELIAL AND MESENCHIMAL TRANSITION IN PROSTATE CANCER CELLS
Authors: BAL Esra , DEVECİ ÖZKAN Asuman , BETTS Zeynep 
Published: October 2023

Objective: The difficulties experienced in the treatment of prostate cancer and the excess of side effects due to chemotherapy have brought the search for alternative treatment strategies. In recent studies, it is known that Rutin (RUT) has an anti-cancer effect on cancer cells. Our study aimed to determine the effects of RUT on epithelial-mesenchymal transition (EMT) in prostate cancer cells, for the first time.
Methods: The anticancer activity of RUT in prostate cancer cells (PC-3) was determined by WST-1, Annexin V ELISA, DAPI and Acridine Orange staining, and the anti-cancer and anti-metastatic properties of RUT were evaluated with the Scratch Assay test. The mRNA expression level of Bax, Bcl-2, Snail, Twist, Vimentin and E-cadherin genes was determined by RT-PCR.
Results: PC-3 cells were treated with RUT (500, 750, 1000, 1500 µM) for 24 and 48 hours. The viability rates decreased with increasing RUT concentration depending on dose and time (p
ARTIFICIAL INTELLIGENCE BASED RATING OF CARPAL TUNNEL SYNDROME EFFICACY IN CLINICAL DIAGNOSIS
Authors: SARICA  DAROL Elif , ECE Yıldız , UZUN Süleyman , ALEMDAR Murat 
Published: October 2023

Objective: The most common entrapment neuropathy seen by the clinician is Carpal tunnel syndrome (CTS). CTS is graded as mild, moderate, and severe according to the results obtained on electroneuromyography (ENMG) by clinicians. We aimed to show the effectiveness of the use of artificial intelligence in clinical diagnosis in the grading of CTS.
Methods: In our study, the data of 315 people with a pre-diagnosis of CTS were used and classified into four classes based on AI as CTS grade. Machine Learning (ML) algorithms Ensemble, Support Vector Machine (SVM), K-Nearest Neighbor (KNN), and Decision Tree (Tree) algorithms were used in classification processes. 10% Hold-out validation was used and the learning rate was determined as 0.1. As a result of the classification, accuracy, precision, sensitivity, specificity, and F1-score performance values were obtained.
Results: SVM made the best estimation and KNN made the worst estimation in the 0 class. The best estimate in class 1 belongs to the Support Vector Machine. Ensemble and Tree made the best guesses in the 2nd and 3rd grades. In our study, the best algorithm with an overall success rate is SVM with 93.55%.
Conclusions: The results showed that ML algorithm models consistently provided better predictive results and would assist physicians in determining the medical treatment modality of CTS. Artificial intelligence (AI) techniques are reliable methods that assist clinicians to deliver quality healthcare.
Folded-Stent: The Third Generation Trick to Improve The Microvascular Stenting Technique
Authors: PAMUK Çağdaş 
Published: October 2023

Objective: Although microsurgical vessel anastomoses have become a routine procedure today, they are still among the difficult techniques to apply. The most important step in the success of the technique is the clear presentation of the vessel lumen. In this study, we aimed to describe a new technique that will provide an easier anastomosis by keeping the lumen open during microvascular anastomoses.
Methods: Four groups were formed using the chicken wing radial artery, which is an inanimate animal model. One of these was the control group who underwent standard microvascular repair. The second and third groups that followed were those in which two previously defined intravascular stenting techniques were applied. The fourth group was the Folded stent group that we just defined.
Results: Anastomosis time was found to be significantly longer when compared to other groups in our newly defined technique. This time was an average of 3 minutes. No significant difference was observed in terms of the number of sutures used in anastomoses. No posterior wall suture complication was observed in any specimen.
Conclusions: “Folded-Stent” technique provides a great advantage over other stenting techniques in terms of keeping the lumen open during the anastomosis and preventing the adhesion of the vessel walls. It is an advantageous technique that can be used in clinical practice, especially during venous repairs, to prevent posterior wall suturing of small caliber vessels.
Evaluation of colonoscopy and pathology results of patients who underwent colonoscopy due to fecal occult blood test positivity: A single center experience
Authors: SUBAŞI Özkan , TURGUT Hamdi Taner , GUNES Abdullah , DİNDAR Gokhan 
Published: October 2023

Objective: The most important part of improving colorectal cancer prognosis is to detect and treat in the early stage. The most effective way to do this is screening programs. Fecal occult blood test is one of the most frequently used methods in the screening program. In this study, we aimed to evaluate the colonoscopy and histopathological findings of patients who underwent colonoscopy due to positive fecal occult blood test.
Methods: Patients who had a positive fecal occult blood test between January 2016 and December 2018 and underwent colonoscopy to investigate the etiology were included in the study. Demographic characteristics, colonoscopy findings and histopathological results of the patients were reviewed retrospectively from hospital records.
Results: A total of 325 patients were included in the study. Of the patients, 146 (44.9%) were male, 179 (55.1%) were female, and their mean age was 58.4±9.3 years. Colonoscopic findings of 140 patients (43.1%) were normal. Polyps in 89 (27.4%) patients, perianal disease in 46 (15.1%), diverticulum in 20 (6.2%), inflammatory bowel disease in 8 (2.4%), solitary rectal ulcers in 4 (1.2%) patients and colorectal cancer in 18 (5.5%) of them was detected.
Conclusion: Fecal occult blood test is a cost-effective and easy-to-apply method used in colorectal cancer screening programs together with colonoscopy, helping to detect both cancer and precancerous lesions and increase the survival rate.
Antineutrophil cytoplasmic antibody serotypes may affect the clinical presentation of patients with granulomatosis with polyangiitis: a single-center, retrospective cross-sectional study
Authors: YAZICI Ayten , SADİOĞLU ÇAĞDAŞ Öznur , ARISAL Ali Osman , ÖZDEMİR IŞIK Özlem , GÖKÇEN Neslihan , ÇEFLE Ayşe 
Published: October 2023

Objective: Granulomatosis with polyangiitis (GPA) is one of the systemic vasculitis included in antineutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). Clinical characteristics, ANCA serotypes, and their frequencies vary depending on the type of vasculitis. In this study, we aimed to investigate the link between ANCA serotypes and clinical variables documented at the time of admission.
Methods: This study was a retrospective cross-sectional study including 40 patients with GPA. The demographic, clinical, laboratory, and radiological findings were extracted from medical records. Logistic Regression Analysis was performed to estimate the relationship between ANCA serotypes and other variables.
Results: The mean age was 53.95±12.94 years, and there was a delay of 15.85±23.03 months in diagnosis. While constitutional symptoms were observed in 42% of patients, symptoms related to ear-nose-throat in 70%, lung in 87.5%, kidney in 62.5%, neurological findings in 30%, eye in 25%, skin in 25% and musculoskeletal system findings in 90% were noted. Male gender was seen more frequently in cANCA (60.7%) positive patients; however, pANCA-positive patients were mainly female (83.3%) (p=0.050). Delay in diagnosis was longer (p=0.001) and subglottic stenosis was more common (p
Does aspartate aminotransferase platelet ratio index predict gestational diabetes mellitus? A retrospective cohort study.
Authors: İBANOĞLU Müjde Can , YILMAZ ERGANİ Seval , ŞAHİN Büşra , ONCU Hande Nur , İSKENDER Cantekin , USTUN Yaprak 
Published: October 2023

Objective: Our aim was to determine the significance of aspartate aminotransferase platelet ratio index (APRI), neutrophil to lymphocyte ratio (NLR), and platelet-to-lymphocyte ratio (PLR) in predicting gestational diabetes mellitus (GDM) at first trimester screening in a retrospective study of pregnant women.
Method: In this study, a retrospective analysis of pregnant women (n=216) screened at the antenatal clinic and diagnosed with gestational diabetes between 24-28 weeks of gestation was performed. APRI score, NLR and PLR were calculated in the blood of these pregnant women in the first trimester and compared with the results of patients in the control group (n=250).
Results: The ROC -analysis for APRI yielded an AUC value of 0.489 (p=0.684). Maternal age was found to be an independent risk factor for GDM. The risk increased 1.162-fold with increasing maternal age (p < 0.001). The optimal cutoff value for NLR was 3.55, sensitivity was 65%, specificity was 49%, and the area under the ROC curve was 0.544.
Conclusion: In the results we compared with those of the control group, we found no significant change in APRI value and PLR. However, we found that NLR has a predictive value for GDM.
SEKONDER PROGRESİF MULTİPL SKLEROZDA KLİNİK, DEMOGRAFİK VE RADYOLOJİK ÖZELLİKLER: TEK MERKEZ DENEYİMİ
Authors: BÜNÜL Sena Destan , EFENDİ Hüsnü 
Published: October 2023

ÖZ
Amaç: Multipl sklerozis (MS) inflamasyon, demiyelinizasyon ve akson hasarı ile karakterize ak madde ön planda olmak üzere, korteks ve derin gri maddeyi de etkileyebilen otoimmün bir santral sinir sistemi hastalığıdır. Relapsing remitting Multipl skleroz (RRMS) ve sekonder progresif Multipl skleroz (SPMS) dönemlerindeki hastaların demografik, klinik ve radyolojik özellikleri değerlendirilerek progresyonu ön gördürücü faktörlere katkı sağlamak amaçlanmıştır.
Yöntem: Kocaeli Üniversitesi Tıp Fakültesi Nöroloji Anabilim Dalı Multipl Skleroz polikliniğinde takip edilen MS hastalarından RRMS ve SPMS grubundaki hastaların verileri veri tabanından kaydedilmiştir. İki grup klinik, demografik ve radyolojik bulgular açısından karşılaştırılarak değerlendirilmiştir.
Bulgular: Çalışmaya 121 SPMS ve 802 RRMS hastası dahil edildi. Her iki grup arasında yaş, cinsiyet, eğitim durumu gibi demografik özellikler ve MS tanısı aldıklarındaki yaşları arasında anlamlı farklılık bulunmadı. Hastalık süresi SPMS’lerde RRMS’lere göre daha uzun bulundu. EDSS, SPMS’lerde RRMS’lere göre daha yüksek bulundu. Son 12 aydaki klinik atak öyküsü ve radyolojik bulgulardaki aktivite RRMS’lerde SPMS’e göre daha yüksek bulundu. Spinal bulgularla başlayan hastaların oranı ise SPMS grubunda daha yüksekti.
Sonuç: SPMS'yi klinik olarak tanımlamak için genel olarak kabul gören standartlaştırılmış bir değerlendirme yoktur. Klinik ve radyolojik bulgular eşliğinde yapılan çalışmalar arttıkça progresyon tanısı ve ön gördürücü faktörler ile ilgili bilgiler netlik kazanacaktır.
Políticas públicas en materia de Seguridad Ciudadana durante el Gobierno de Sebastián Piñera (2010-2011)
Authors: Frühling Hugo 
Published: October 2023

Este trabajo examina las orientaciones generales de las propuestas de Sebastián Piñera en materia de delincuencia, comparándolas con las que guiaron a sus predecesores. Se analiza el avance de las propuestas realizadas durante su campaña y posteriormente durante el primer año de gobierno a fin de establecer el grado de cumplimiento de las promesas gubernamentales. Por último, se realiza un balance de la aplicación de las políticas en esta área.
Dinamika Sosial Dalam Proses Pengambilan Keputusan dalam Manajemen Pendidikan Islam
Authors: Efendi Nur , Ibnu Sholeh Muh 
Published: October 2023

Penelitian ini mempunya tujuan untuk mengetahui aspek penting dalam analisis dinamika sosial dalam pengambilan keputusan di lembaga pendidikan islam. Bagaimana proses pengambilan keputusan yang tepat, efektif, dan sesuai dengan nilai-nilai agama islam. Menegetahui faktor sosial yang mempengaruhi keputusan, dan bagaimana dampak dinamika sosial terhadap kualitas keputusan. Metode yang digunakan dalam penelitian ini adalah metode penelitian kepustakaan. Data diperoleh dari berbagai sumber seperti jurnal ilmiah, buku, makalah seminar, dan publikasi lain yang terkait baik offline maupun online. Analisis data ini terdiri dari pengumpulan data, reduksi data, penyajian data, dan penarikan kesimpulan Hasil penelitian ini menunjukkan aspek penting analisis dinamika sosial pengambilan keputusan antaralain kepentingan beragam, interaksi kelompok, kultur dan norma, kepemimpinan, resistensi dan konflik, partisipasi dan inklusivitas, keterbukaan komunikasi, konsensus dan persetujuan,pengaruh eksternal dan pengembangan kapasitas. Proses pengambilan keputusan yang tepat, efektif, dan sesuai dengan nilai-nilai agama islam ini mencakup seperti identifikasi masalah, pengumpulan data dan informasi, analisis dan evaluasi, konsultasi dan musyawarah, penentuan tujuan dan kriteria keputusan, pemilihan opsi keputusan, implementasi, monitoring dan evaluasi, penyesuaian dan perbaikan, dan keterbukaan dan transparansi. Faktor sosial yang mempengaruhi keputusan diantaranya kebutuhan dan permintaan masyarakat, nilai-nilai dan ajaran agama, budaya lokal, pengaruh keluarga dan orang tua, peran pemimpin dan pengelola, tuntutan global, situasi ekonomi, pengaruh media dan teknologi, kepentingan politik, dan kepedulian sosial. Dampak dinamika sosial terhadap kualitas keputusan antara lain kualitas keputusan yang beragam, legitimasi dan penerimaan, pengambilan keputusan yang lebih komprehensif, dampak positif pada implementasi, penyelesaian konflik, adaptasi terhadap perubahan, pengelolaan sumber daya yang efisien, dan penciptaan iklim belajar yang positif
Response of Citrus aurantium L. orange seedlings to the addition of NPK complex nanofertilizer and humic and their effect on vegetative traits and nutrients.
Authors: Hamid Hammood Mahawesh  
Published: October 2023

The study was carried out at University of Thi-Qar on 02.02.2023; the experience finished on 15.06.2023 on Citrus seedlings at one year age, by three seedlings for each experimental unit. Thus the number of seedlings was 81 at anvils plastic, which was filed by soil and peatmoss at a ratio of 3:1. The experiment included fertilizer treatment Nano NPK which spray on plant leaves at concentrations (0, 0.5, 1) g. l, by three additions at 15 days period between each addition. Humic acid was added to the Spray the plant three times (0, 1, 2) g. The experiment was carried out by three replication according to Randomized Complete Block Design (RCBD). The results were compared according to less difference test than 5 % possibility.
Spraying treatments with nano-fertilizer npk showed a positive effect on most of the vegetative and chemical indicators of orange seedlings. The spraying treatment at a concentration of 1 gm l-1 was significantly superior by recording the highest rate for the number of plant leaves, stem thickness, leaf content of carbohydrates, and leaf content of the nutrients calcium, magnesium, and sulfur. It reached 61.78 leaves. Seedling-1, 7.77 cm, 10.21%, 155.62%, 0.268%, 38.046%, respectively.
The average spray treatments with Humic showed a positive effect on most of the vegetative and chemical indicators of Citrus aurantium L. orange seedlings. The spray treatment at a concentration of 1 gm L-1 was superior in recording the highest rates for the number of plant leaves and stem thickness, as they reached 64.78 and 8.77, respectively. The spraying treatment at a concentration of 1 gm L-1 also excelled by recording the highest rate for the leaf content of carbohydrates and the leaf content of the nutrients calcium, magnesium and sulfur, reaching 10.01%, 156.53%, 0.257%, 36.06%.
The interaction treatments between the two study factors gave a positive, significant effect on most of the vegetative and chemical traits studied. The interaction treatment between the concentration of 1 gm L-1 of nano-NPK and 1 gm L-1 Humic recorded the best results significantly for growth indicators.
Impact of Drinking Water on People’s Health and Water Borne Diseases
Authors: Yasmeen Qamar , Yasmeen Summaira 
Published: October 2023

Poor water quality is a result of a variety of sources, including human, animal and industrial wastes, by consuming such unhygienic water, there is a risk of contracting waterborne diseases and infections. Objective: To explore impact of drinking water on health of people and related waterborne diseases due to poor quality of drinking water. Methods: From March 2022 to June 2022, a cross-sectional study was carried out to assess the drinking water quality and any concomitant health concerns. The areas with the highest illness ratios were selected using convenient sampling technique. Total 277 participants both male and female participated in this study. Multiple choice questions (MCQs) and rating questions on a Likert scale were the two formats used in questionnaire. Results: According to survey area demographic data, 84.1% of respondents were living in joint families, and 63.5% of respondents were male. However, the respondents' literacy rate was below average. Motor pumps made up the majority of the water supply (60.6%). The majority of participants (84.8%) firmly believed that the quality of the water they consume has an impact on their health. The majority of respondents (56.3%) stated that water-borne illnesses such cholera, typhus, and stomach ailments affected children in their community. Conclusions: It was determined that the majority of the population reported higher disease development and expressed dissatisfaction with the quality of their drinking water. Also, education and economic conditions of a person can play an important role in health management and more access to better quality of drinking water.
Caracterización florística y pisos de vegetación en los andes de Santiago, Chile central
Authors: Muñoz-Schick Mélica , Moreira-Muñoz Andrés , Villagrán Carolina , Luebert Federico 
Published: October 2023

Se presentan los resultados de un estudio florístico y vegetacional realizado en la cuenca superior del Río Maipo, Andes de Chile Central (33°34'-34°14' S, 69°48'-70°30' O). Se efectuaron tres transectos altitudinales, en las laderas de los siguientes cajones: Río Maipo (1.200-3.400 msnm), Río Yeso (1.200-4.000 msnm) y Estero El Sauce (800-2.200 msnm).
El análisis de la flora vascular comprende un total de 357 especies, agrupadas en 209 géneros y 75 familias. La mayor parte de las especies corresponde a nativas no endémicas (54%), aunque el porcentaje de endemismo también es alto (29 %.) Se aprecia una paulatina disminución del nivel de endemismo a medida que se asciende en el transecto altitudinal, debido a que los pisos más altos reciben una mayor influencia de especies provenientes de la vertiente oriental de la cordillera.
Para la vegetación zonal se identificaron cinco pisos vegetacionales que se suceden en el gradiente altitudinal: a)Matorral Esclerófilo, b) Matorral Subandino, c)Matorral Andino, d) Estepa Altoandina, e) Desierto Altoandino. La cobertura media de la vegetación tiende a disminuir a medida que se asciende en el transecto altitudinal, desde 100%a 800 msnm hasta 5% a 3.400 msnm. Al comparar los límites altitudinales que presentan estas unidades en los diferentes transectos, destaca la extensión del Matorral Andino en el Río Maipo, dependiente más moderada, en que dominados especies arborescentes raras en Chile, Adesmia obovata y A. pinifolia.
El análisis de la distribución geográfica de las especies muestra que los elementos andino-mediterráneos predominan en los pisos superiores de los transectos, mientras que los elementos chileno-centrales predominan en los pisos bajos. El análisis comparativo en el transecto altitudinal, confirma el carácter de transición del Matorral Subandino, en que los elementos chileno-centrales son reemplazados por los andino-mediterráneos.