bluuebunny/crossref_metadata_2025_split huggingface dataset:
Oxygen isotopic compositions of fresh rooftop micrometeorites from the Budel collection—Insights into the contemporary cosmic dust flux
Authors: Jonker Guido , van Maldeghem Flore , van Ginneken Matthias , Krämer Ruggiu Lisa , Goderis Steven 
Published: February 2024

AbstractCosmic dust particles originate from a wide variety of solar system and interstellar objects, including sources not identified among meteorite collections. Particles that survive atmospheric entry are retrieved on the Earth's surface as micrometeorites. The recovery of these micrometeorites has recently advanced to rooftop sites. Here, we present the results of an extensive isotopic study on this type of rooftop micrometeorite from the Budel collection, the Netherlands, accreted to the Earth between October 31, 2018 and June 16, 2021. The triple oxygen isotopic compositions of 80 silica‐dominated cosmic spherules (CSs) with diameters ranging between 105 and 515 μm are obtained relying on 213 in situ spot analyses determined using ion microprobe. Our analyzed population spans a large range of isotopic compositions and is dominated by carbonaceous chondritic sources. In situ measurements on several CSs support a possible continuum between 16O‐rich and 16O‐poor compositions following the CM mixing line, showing that 16O‐poor CSs may be genetically related to aqueously altered carbonaceous chondrites. We demonstrate that weathering in the terrestrial environment has negligible effects on the isotopic compositions of the studied CSs and attempt to quantify the effects of kinetic mass‐dependent fractionation and admixture of terrestrial oxygen during atmospheric entry. The results further corroborate previously suggested relations between CS texture and the duration and intensity of the heating pulse experienced during atmospheric deceleration. Finally, the young and well‐constrained terrestrial age of the collection provides insights into the most recent flux of cosmic dust. Our results indicate no major recent changes in the global flux compared with collections sampled over thousand‐ to million‐year time scales and demonstrate that 16O‐poor material is still represented in the modern‐day cosmic dust flux at a relative abundance of ~13%–15%. As such, rooftop micrometeorites represent a valuable reservoir to study the characteristics of the contemporary cosmic dust flux.
Positive selection in gamete interaction proteins in Carnivora
Authors: Pisciottano Francisco , Campos María Clara , Penna Clementina , Bruque Carlos David , Gabaldón Toni , Saragüeta Patricia 
Published: February 2024

AbstractThe absence of robust interspecific isolation barriers among pantherines, including the iconic South American jaguar (Panthera onca), led us to study molecular evolution of typically rapidly evolving reproductive proteins within this subfamily and related groups. In this study, we delved into the evolutionary forces acting on the zona pellucida (ZP) gamete interaction protein family and the sperm‐oocyte fusion protein pair IZUMO1‐JUNO across the Carnivora order, distinguishing between Caniformia and Feliformia suborders and anticipating few significant diversifying changes in the Pantherinae subfamily. A chromosome‐resolved jaguar genome assembly facilitated coding sequences, enabling the reconstruction of protein evolutionary histories. Examining sequence variability across more than 30 Carnivora species revealed that Feliformia exhibited significantly lower diversity compared to its sister taxa, Caniformia. Molecular evolution analyses of ZP2 and ZP3, subunits directly involved in sperm‐recognition, unveiled diversifying positive selection in Feliformia, Caniformia and Pantherinae, although no significant changes were linked to sperm binding. Structural cross‐linking ZP subunits, ZP4 and ZP1 exhibited lower levels or complete absence of positive selection. Notably, the fusion protein IZUMO1 displayed prominent positive selection signatures and sites in basal lineages of both Caniformia and Feliformia, extending along the Caniformia subtree but absent in Pantherinae. Conversely, JUNO did not exhibit any positive selection signatures across tested lineages and clades. Eight Caniformia‐specific positive selected sites in IZUMO1 were detected within two JUNO‐interaction clusters. Our findings provide for the first time insights into the evolutionary trajectories of ZP proteins and the IZUMO1‐JUNO gamete interaction pair within the Carnivora order.
Plant–pathogen interaction with root rot of Panax notoginseng as a model: Insight into pathogen pathogenesis, plant defence response and biological control
Authors: Li Jianbin , Ai Mingtao , Hou Jiae , Zhu Peiqi , Cui Xiuming , Yang Qian 
Published: February 2024

AbstractPlant diseases are a major threat affecting the sustainability of global agriculture. Although the breeding of new resistant cultivars is considered to be the primary approach to prevent and control plant diseases, it is dependent on an in‐depth understanding of plant–pathogen interactions. At present, we have an in‐depth understanding of the interactions between model plants and pathogens, such as Arabidopsis thaliana and rice, but we are still in the beginning stage for more non‐model plants (e.g., medicinal plants). Panax notoginseng is the primary source of the high‐value active ingredient triterpenoid saponins. Root rot disease in P. notoginseng has attracted research attention because of its high destructiveness. Understanding the infection stages and strategies of pathogens, plant resistance mechanisms and induced plant defence against pathogens is essential to support agricultural sustainable development of P. notoginseng. Here, we review and summarize, with root rot of P. notoginseng as a model, the current knowledge of plant–pathogen interaction, and feasability of use of microorganisms and secondary metabolites as sources of biological control agents at a low cost. Finally, we also discuss the importance of plant–pathogen interactions in resistance breeding, thereby providing a new strategy to develop green agriculture for non‐model plants.
Isoflurane anesthesia suppresses gastric myoelectric power in the ferret
Authors: Tomaselli Lorenzo , Sciullo Michael , Fulton Stephanie , Yates Bill J. , Fisher Lee E. , Ventura Valérie , Horn Charles C. 
Published: February 2024

AbstractBackgroundGastric myoelectric signals have been the focus of extensive research; although it is unclear how general anesthesia affects these signals, and studies have often been conducted under general anesthesia. Here, we explore this issue directly by recording gastric myoelectric signals during awake and anesthetized states in the ferret and explore the contribution of behavioral movement to observed changes in signal power.MethodsFerrets were surgically implanted with electrodes to record gastric myoelectric activity from the serosal surface of the stomach, and, following recovery, were tested in awake and isoflurane‐anesthetized conditions. Video recordings were also analyzed during awake experiments to compare myoelectric activity during behavioral movement and rest.Key ResultsA significant decrease in gastric myoelectric signal power was detected under isoflurane anesthesia compared to the awake condition. Moreover, a detailed analysis of the awake recordings indicates that behavioral movement is associated with increased signal power compared to rest.Conclusions & InferencesThese results suggest that both general anesthesia and behavioral movement can affect the signal power of gastric myoelectric recordings. In summary, caution should be taken in studying myoelectric data collected under anesthesia. Further, behavioral movement could have an important modulatory role on these signals, affecting their interpretation in clinical settings.
Iranian classical dance as a subject for empirical research: An elusive genre
Authors: Christensen Julia F. , Khorsandi Shahrzad , Wald‐Fuhrmann Melanie 
Published: February 2024

AbstractDance has entered mainstream empirical research: dance as an experimental stimulus, and dancers as movement experts. Informed by several sources, including primary sources (original, historical documents, and oral reports, such as interviews with practitioners and academic scholars of Iranian dance genres) and secondary sources (research literature), we describe what we label “Iranian classical dance” within this paper as an important resource for empirical research, not only in humanities scholarship but also, and importantly, for empirical aesthetics, emotion psychology, cross‐cultural psychology, and affective neuroscience. For this purpose, we (1) describe the aesthetics, characteristics, and history of Iranian classical dance; (2) outline issues of definition and systematization; and (3) give an overview of the cultural complexities and sociopolitical issues regarding Iranian classical dance in the past 40 years, which have shaped its current form. After the political revolution of 1979 (Iranian solar calendar year: 1358), dance in Iran—both as everyday practice and as a cultural heritage—was first forbidden, and now remains heavily restricted. International, interdisciplinary research teams can contribute to safeguarding Iranian classical dance in the future by firmly enshrining it into empirical research on human dance. We outline empirical research perspectives on Iranian classical dance, dataset resources, and expert communities.
Comparing paediatric optometric vision care in Canada over a 14‐year period
Authors: Christian Lisa W. , Opoku‐Yamoah Victor , Rose Kalpana , Jones Deborah A. , McCulloch Daphne , Irving Elizabeth L. , Leat Susan J. 
Published: February 2024

AbstractPurposeIn Canada, teaching in paediatric eye care has increased in the past decade both within the optometry curriculum and as continuing education to optometrists. Paediatric vision care guidelines have also been established by North American optometric associations. This study examined whether this exposure was associated with changes in paediatric eye care in Canada over a 14‐year period.MethodsCanadian optometrists were invited to participate in an anonymous 35‐item survey in 2007 and 2021. The surveys sought to investigate optometrist's recommendations for first eye examinations, the number of paediatric patients seen in a typical week and preparedness to provide eye examinations to children. Response frequencies were determined for each survey item.ResultsAcross Canada, 133/1000 (13.3%) and 261/~6419 (~4.1%) optometrists responded to the survey in 2007 and 2021, respectively. No significant difference was found in the number of years practicing, days per week in practice and total number of patients seen per week. The modal age optometrists recommended children be seen for their first eye examination changed from 3–4 years in 2007 (53%) to 6–12 months in 2021 (61%). In 2007, 87% of respondents provided eye examinations to children <2 years, increasing to 94% in 2021 (p = 0.02). Despite a reduction in the recommended age between the two survey years, the most frequent age children were seen for their first eye examination was 3‐4 years (30% in both surveys) and the most common age seen in a typical week remained unchanged (4–6 years—56% 2007; 66% 2021).ConclusionAlthough optometrists' willingness to provide paediatric eye care increased over the past 14 years, the number of children seen in a typical week did not change. Barriers to determine why more children are not being seen at an earlier age need to be investigated.
Treatment ofL5‐S1Floating Calcified Lumbar Disc Herniation with Percutaneous Endoscopic Interlaminar Discectomy
Authors: Gu GuoNing , Liu Teng , Guo HuiZhi , Tang YongChao , Zhang ShunCong , Yang ZhiDong , Li YongXian , Yuan Kai 
Published: February 2024

ObjectiveThe floating calcified tissue in floating calcified lumbar disc herniation (FCLDH) is hard and often adheres to the dura mater, which can easily cause nerve root damage during surgery, making the operation challenging. We proposed the classification of FCLDH and a new technique for removing floating calcified tissue and reported the clinical efficacy and safety of this new technique in clinical practice.MethodsFrom January 2019 to October 2021, 24 patients (13 males and 11 females, 46.4 ± 7.72 years) with L5‐S1 floating calcified lumbar disc herniation were treated with percutaneous endoscopic interlaminar discectomy (PEID). According to FCLDH classification, a total of Type Ia: nine cases, Type Ib: five cases, Type IIa: four cases, and Type IIa: six cases were included. The visual analogue scale (VAS) and Oswestry disability index (ODI) were recorded pre‐operatively and 3 days postoperatively, 6 months postoperatively, and at the last follow‐up. The postoperative curative effect was evaluated according to the modified MacNab criteria. Computed tomography (CT) and magnetic resonance imaging (MRI) of the lumbar spine were performed 3 days after surgery to evaluate the efficacy of the surgery.ResultsAll patients successfully underwent PEID. The VAS and ODI scores at 3 days postoperatively, 6 months postoperatively, and at the last follow‐up were significantly improved and statistically significant compared to those of the preoperative period (p < 0.05). All the patients were followed up for 12–24 months (mean, 16.6 ± 4.6 months). At the last follow‐up, according to the modified MacNab criteria, 15 cases were excellent, eight were good, and one was fair. The combined excellent and good rate was 95.83% (23/24). Postoperative review revealed that all floating calcified tissues were effectively removed and the nerve roots were adequately decompressed without complications such as cerebrospinal fluid leakage and lumbar spine infection.ConclusionThe classification of FCLDH we proposed can well guide the selection of surgical plans. PEID combined with floating calcified tissue removal technology has good efficacy in the treatment of L5‐S1 FCLDH, ensuring accurate removal of calcified tissue, reducing complications and improving the quality of life of affected individuals.
Eight‐month intensive meditation‐based intervention improves refractory hallucinations and delusions and quality of life in male inpatients with schizophrenia: a randomized controlled trial
Authors: Xue Ting , Sheng Jialing , Gao Hui , Gu Yan , Dai Jingjing , Yang Xianghong , Peng Hong , Gao Hongrui , Lu Ruping , Shen Yi , Wang Li , Wang Lijun , Shi Yuan , Li Zezhi , Cui Donghong 
Published: February 2024

AimThis study investigated the impact of an 8‐month daily‐guided intensive meditation‐based intervention (iMI) on persistent hallucinations/delusions and health‐related quality of life (QoL) in male inpatients with schizophrenia with treatment‐refractory hallucinations and delusions (TRHDs).MethodsA randomized controlled trial assigned 64 male inpatients with schizophrenia and TRHD equally to an 8‐month iMI plus general rehabilitation program (GRP) or GRP alone. Assessments were conducted at baseline and the third and eighth months using the Positive and Negative Syndrome Scale (PANSS), 36‐Item Short Form‐36 (SF‐36), and Five Facet Mindfulness Questionnaire (FFMQ). Primary outcomes measured PANSS reduction rates for total score, positive symptoms, and hallucinations/delusions items. Secondary outcomes assessed PANSS, SF‐36, and FFMQ scores for psychotic symptoms, health‐related QoL, and mindfulness skills, respectively.ResultsIn the primary outcome, iMI significantly improved the reduction rates of PANSS total score, positive symptoms, and hallucination/delusion items compared with GRP at both the third and eighth months. Treatment response rates (≥25% reduction) for these measures significantly increased in the iMI group at the eighth month. Concerning secondary outcomes, iMI significantly reduced PANSS total score and hallucination/delusion items, while increasing scores in physical activity and mindfulness skills at both the third and eighth months compared with GRP. These effects were more pronounced with an 8‐month intervention compared with a 3‐month intervention.ConclusionsAn iMI benefits patients with TRHDs by reducing persistent hallucinations/delusions and enhancing health‐related QoL. Longer iMI duration yields superior treatment outcomes.
What is Philosophy of the Geosciences?
Authors: Ohnesorge Miguel , Watkins Aja 
Published: February 2024

AbstractThe philosophy of the geosciences is an emerging subfield in philosophy of science. Although past and present geoscientific disciplines differ substantially, we argue that they frequently face common epistemological and ethical problems. We survey several of these problems that have already attracted sustained philosophical interest, related to the use of measurements, data, and models to study relatively inaccessible target phenomena, responses to (epistemic) injustices, and the management of epistemic risks.
Cryptic sexual reproduction in an emerging Eucalyptus shoot and foliar pathogen
Authors: Pham Nam Q. , Suzuki Hiroyuki , Duong Tuan A. , Wingfield Brenda D. , Barnes Irene , Durán Alvaro , Wingfield Michael J. 
Published: February 2024

AbstractEucalyptus scab and shoot malformation is an emerging disease and a serious threat to the global plantation forestry industry. The disease appeared in North Sumatra (Indonesia) in the early 2010s and the causal agent was recently described as a novel species, Elsinoe necatrix. Nothing is known regarding its possible origin or why it emerged rapidly to cause a serious local epidemic. To investigate its population biology, we developed 15 polymorphic microsatellite markers as well as mating‐type markers using genome sequences for two E. necatrix isolates. Isolates of the pathogen were collected from different host varieties at four locations in the Lake Toba region of North Sumatra and characterized using these markers. A high level of genotypic diversity was observed for all populations with little to no genetic differentiation between sampling areas. Discriminant analysis of principal components, genotype networks and analysis of molecular variance all showed a lack of population structure and a high level of gene flow among sampling regions. Mating‐type ratios and linkage disequilibrium analyses suggest that sexual recombination is likely to be occurring, although a sexual state has not been found for the pathogen. The results of this study highlight the fact that new genotypes of E. necatrix, probably arising from cryptic sexual recombination, will challenge efforts to manage the disease, and that breeding and selection for tolerance will require substantial host genetic diversity.
Transcriptomics and metabolomics revealed the synthesis and potential role of flavonoids in pea roots under continuous cropping obstacles
Authors: Ma Lei , Ma Shaoying , Chen Guiping , Lu Xu , Zhang Congcong , Wei Ruonan , Feng Xiaojie , Xu Ling , Zhang Xucheng , Chai Qiang , Li Sheng 
Published: February 2024

AbstractWith the continuation of intensive and monoculture production in modern agriculture, the harm of continuous cropping obstacles is becoming more prominent. Pea has important nutritional and economic value, but it is easy to have continuous cropping obstacles in production. However, there is limited knowledge of the regulatory mechanisms of pea to cope with continuous cropping obstacles. In this study, we found that the number of differential expressed genes (DEGs) and differential metabolites (DAMs) increased in the pea roots with increasing continuous cropping times, and the number of DEGs and DAMs in roots of sensitive pea was more than that of continuous cropping tolerant pea. Comprehensive analysis of the omics data revealed that the flavonoid and isoflavonoid biosynthesis pathways play key roles in the response of pea roots to the continuous cropping obstacles. Most of the DEGs involved in these two pathways were up‐regulated. Meanwhile, most of the flavonoid compounds and total flavonoid content increased. With increasing continuous cropping times, the isoflavones category in DAMs increased, and the isoflavones category in the roots of continuous cropping tolerant pea were higher than in sensitive pea. Additionally, the isoflavonoid (biochanin A, calycosin, genistein) in the roots of continuous cropping tolerant pea have the ability to inhibit the growth of fungi in pea soil and possess antioxidant activity. These findings revealed the important role of flavonoids in pea continuous cropping obstacles and laid a foundation for effectively alleviating pea continuous cropping obstacles in the future.
Is the application of bioactive anti‐stress substances with a seaweed‐derived biostimulant effective under adequate growth conditions?
Authors: Velasco‐Clares Daniel , Navarro‐León Eloy , Atero‐Calvo Santiago , Ruiz Juan M. , Blasco Begoña 
Published: February 2024

AbstractThe use of biostimulants in agriculture is currently emerging as a resource to increase crop productivity and quality. Additionally, the concurrent application of other bioactive materials or bioregulators alongside biostimulants can prove valuable in mitigating oxidative stress induced by various abiotic stresses. However, in some cases, these compounds applied at inadequate doses produce toxic effects under non‐stressful conditions. Therefore, the objective of this study was to analyze the effects of applying various doses of a seaweed‐derived biostimulant containing additional bioactive compounds (Cytolan® Stress) under optimal growth conditions. Lettuce plants were grown under control conditions without biostimulants (control plants) and with two biostimulants Cytolan® (seaweed‐derived biostimulant with proline) and Cytolan® Stress applied foliarly at three doses (150, 300, and 500 mL/hL). Growth and quality parameters and physiological processes within primary and secondary metabolism were analyzed. The results identified the 300 mL/hL dose of Cytolan® Stress as the best treatment. Thus, it improved biomass production, induced photosynthetic activity, increased phytohormone, amino acids (AAs), and mineral nutrient profiles, and stimulated N assimilation. Besides, it substantially enhanced the antioxidant capacity and the concentration of various antioxidant compounds, leading to increased lettuce quality and potential stress tolerance. However, the 500 mL/hL Cytolan® Stress caused phytotoxic effects, underscoring the importance of applying the biostimulant at the proper dose.