bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dosimetry of [18F]TRACK, the first PET tracer for imaging of TrkB/C receptors in humans
Authors: Thiel Alexander , Kostikov Alexey , Ahn Hailey , Daoud Youstina , Soucy Jean-Paul , Blinder Stephan , Jaworski Carolin , Wängler Carmen , Wängler Björn , Juengling Freimut , Enger Shirin A. , Schirrmacher Ralf 
Published: October 2023

Abstract
Background
Reduced expression or impaired signalling of tropomyosin receptor kinases (Trk receptors) are found in a vast spectrum of CNS disorders. [18F]TRACK is the first PET radioligand for TrkB/C with proven in vivo brain penetration and on-target specific signal. Here we report dosimetry data for [18F]TRACK in healthy humans. 6 healthy participants (age 22–61 y, 3 female) were scanned on a General Electric Discovery PET/CT 690 scanner. [18F]TRACK was synthesized with high molar activities (Am = 250 ± 75 GBq/µmol), and a dynamic series of 12 whole-body scans were acquired after injection of 129 to 147 MBq of the tracer. Images were reconstructed with standard corrections using the manufacturer’s OSEM algorithm. Tracer concentration time-activity curves (TACs) were obtained using CT-derived volumes-of-interest. Organ-specific doses and the total effective dose were estimated using the Committee on Medical Internal Radiation Dose equation for adults and tabulated Source tissue values (S values).

Results
Average organ absorbed dose was highest for liver and gall bladder with 6.1E−2 (± 1.06E−2) mGy/MBq and 4.6 (± 1.18E−2) mGy/MBq, respectively. Total detriment weighted effective dose EDW was 1.63E−2 ± 1.68E−3 mSv/MBq. Organ-specific TACs indicated predominantly hepatic tracer elimination.

Conclusion
Total and organ-specific effective doses for [18F]TRACK are low and the dosimetry profile is similar to other 18F-labelled radio tracers currently used in clinical settings.
An arachnoid cyst rupture complicated with subdural hygroma in a middle-aged woman: a case report and review of the literature
Authors: Sabooniha Fakhreddin , Baghershahi Ghasem 
Published: October 2023

Abstract
Background
Arachnoid cysts (ACs) account for about 1% of all intracranial mass lesions. The Sylvian fissure is the most common site of ACs which are usually asymptomatic. Traumatic rupture of arachnoid cysts complicated with subdural hygroma is a relatively rare entity in adults especially in females. There is no consensus on their management and each case could add to previous experiences leading to more uniform therapeutic measurements. This case encompasses a combination of watchful strategy, limited surgery and ultimately successful cyst fenestration which highlights a good outcome without complications by adopting a stepwise procedure.

Case presentation
Here, the case of a 51-year-old Persian woman being presented with a 2-month history of a localized headache which had begun 4 days after a minor head trauma. Early brain computed tomography (CT) obtained in another center at 4th day of post-injury which misinterpreted as an old infarct. Repeated CT in our center revealed a large AC of Sylvian fissure complicated with subdural hygroma. Initially a conservative management pursued but due to worsening of the symptoms, a burr-hole craniotomy performed for hygroma evacuation that subsequently followed by cyst fenestration about 1-month later.

Conclusion
Previous awareness about radiographic characteristics of ACs as well as employing appropriate imaging modality are necessary for correct and timely diagnosis of symptomatic patients after minor head trauma because incidentally found ACs might be the underpinning causes of symptoms. Also, following a multistage therapeutic process along with the involvement of patients in decision-making are of paramount importance.
Endovascular coil-embolization of an unruptured, true UAA during early pregnancy- a case report
Authors: Jannusch Kai , Steuwe Andrea , Schimmöller Lars , Dietzel Frederic , Wilms Lena M. , Weiss Daniel , Ziayee Farid , Fehm Tanja Natascha , Schlimgen Charlotte , Poth Vanessa , Ziegler Reinhold Thomas , Minko Peter 
Published: October 2023

Abstract
Background
True uterine artery aneurysms, especially during pregnancy, are a rare entity and not well understood. Clinical symptoms are unspecific pelvic pain and pressure. Diagnosis can be confirmed by transvaginal color-coded-sonography and/or magnetic resonance imaging. Because of potential risk of rupture, immediate interdisciplinary discussion and treatment planning in the best interests of both mother and child is crucial.

Case presentation
We present a 31-year-old pregnant woman with increasing pelvic pain and pressure. Diagnosis of an unruptured uterine artery aneurysm was confirmed by color-coded-sonography and magnetic resonance angiography. After interdisciplinary consultation, successful endovascular super-selective coil-embolization was performed by using X-ray fluoroscopy. Thus, fetal radiation dose during treatment with 4.33 mGy (VirtualDoseTM) was as low as possible with no immediate harm to the fetus.

Conclusions
Unruptured true uterine artery aneurysms can be successfully treated by endovascular super-selective coil-embolization during early pregnancy with no immediate harm to the fetus.
Embolization of pseudoaneurysms in the ureteral branch of the renal artery
Authors: Saiga Atsushi , Aramaki Takeshi , Sato Rui , Asahara Kazuhisa , Goto Hironori 
Published: October 2023

Abstract
Background
Although transcatheter arterial embolization for pseudoaneurysms is already well-established, ureteral artery pseudoaneurysm embolization is extremely rare. The present case shows a successful transcatheter arterial embolization for pseudoaneurysms in the ureteral branch of the renal artery due to ureteral invasion from gastric cancer.

Case presentation
A 57-year-old female presented with gross hematuria after treatments for poorly differentiated gastric adenocarcinoma. A contrast-enhanced computed tomography revealed pseudoaneurysms around the right ureter with a massive hematoma in the right ureter and bladder. The diagnosis was ureteral branch pseudoaneurysms resulting from possible retroperitoneal invasion due to pelvic lymph node metastasis of gastric cancer. Transcatheter arterial embolization was performed using gelatin particles, successfully controlling her hematuria without complications.

Conclusions
Ureteral branch artery embolization, although extremely rare, may be an effective and safe treatment option.
Financial burden in the form of medical and non-medical out-of-pocket expenses on the family of children admitted to a pediatric intensive care unit in India
Authors: Jagtap Varun Ravindra , Save Sushma , Unki Praveen 
Published: October 2023

Abstract
Background
Pediatric intensive care unit (PICU) admissions can have significant repercussions on families, including financial burdens and psychological distress. Not only do they face the overwhelming concern for their child’s health and well-being, but they are also confronted with a range of practical and financial difficulties. Coping strategies play a vital role in mitigating the negative impact of PICU admissions on families. Various coping mechanisms, such as seeking social support, engaging in problem-solving, and utilizing emotional regulation techniques, can help families navigate the challenges they face. The objectives of the study are to understand the array of financial implications in the form of out-of-pocket expenses (OOPE) and to quantify with a better understanding of the composition of out-of-pocket expenses in the form of medical and non-medical expenses. It also aimed to determine the loss of productive hours in a family and to understand the burden of OOPE in relation to the income of the family.

Methods
This prospective observational study was conducted in the pediatric intensive care unit (PICU) of a tertiary care hospital over a period of 6 months after obtaining permission from the institutional ethics committee. Data pertaining to financial burden was collected with the help of Structured questionnaires which included the following categories travel, meals, accommodation, and incidental expenses were considered as non-medical expenses while all medicine costs and investigations were considered as medical expenses. The quantitative data were presented as the means ± SD as median with 25th and 75th percentiles (interquartile range) and were analyzed using ANOVA (for more than two groups) and independent t test (for two groups).

Results
More than half of the children (39(55.71%)) were not enrolled under any government scheme. The mean value of total medical and non-medical costs was 2525 ± 4035.28 and 2234.29 ± 846.84 Indian rupees. The mean value of total out-of-pocket expenses incurred per day (Indian rupees) on day 1, day 2, day 3, day 4, and day 5 were 1304 ± 587.2, 1208.86 ± 3773.84, 814.57 ± 565.03, 807.71 ± 522.76, and 699.86 ± 807.02 respectively.

Conclusion
Families of children admitted to the pediatric intensive care unit incurred catastrophic health expenditure with the cost of medicine contributing a major share. The lowest income brackets had much higher, more than twice the financial burden compared to the higher income group. Almost all families experienced a high loss of productivity in the form of a number of days lost due to the PICU admission of a child. Enrolment in government schemes helped to reduce OOPEs though better coverage of these schemes is needed.
The role of beta-blocker drugs in critically ill patients: a SIAARTI expert consensus statement
Authors: Guarracino Fabio , Cortegiani Andrea , Antonelli Massimo , Behr Astrid , Biancofiore Giandomenico , Del Gaudio Alfredo , Forfori Francesco , Galdieri Nicola , Grasselli Giacomo , Paternoster Gianluca , Rocco Monica , Romagnoli Stefano , Sardo Salvatore , Treskatsch Sascha , Tripodi Vincenzo Francesco , Tritapepe Luigi 
Published: October 2023

Abstract
Background
The role of β-blockers in the critically ill has been studied, and data on the protective effects of these drugs on critically ill patients have been repeatedly reported in the literature over the last two decades. However, consensus and guidelines by scientific societies on the use of β-blockers in critically ill patients are still lacking.
The purpose of this document is to support the clinical decision-making process regarding the use of β-blockers in critically ill patients. The recipients of this document are physicians, nurses, healthcare personnel, and other professionals involved in the patient’s care process.

Methods
The Italian Society of Anesthesia, Analgesia, Resuscitation and Intensive Care (SIAARTI) selected a panel of experts and asked them to define key aspects underlying the use of β-blockers in critically ill adult patients. The methodology followed by the experts during this process was in line with principles of modified Delphi and RAND-UCLA methods. The experts developed statements and supportive rationales in the form of informative text. The overall list of statements was subjected to blind votes for consensus.

Results
The literature search suggests that adrenergic stress and increased heart rate in critically ill patients are associated with organ dysfunction and increased mortality. Heart rate control thus seems to be critical in the management of the critically ill patient, requiring careful clinical evaluation aimed at both the differential diagnosis to treat secondary tachycardia and the treatment of rhythm disturbance. In addition, the use of β-blockers for the treatment of persistent tachycardia may be considered in patients with septic shock once hypovolemia has been ruled out. Intravenous application should be the preferred route of administration.

Conclusion
β-blockers protective effects in critically ill patients have been repeatedly reported in the literature. Their use in the acute treatment of increased heart rate requires understanding of the pathophysiology and careful differential diagnosis, as all causes of tachycardia should be ruled out and addressed first.
Shadow Labor in Care Services: Why Do South Korean Women Care Workers Work Such Long Hours and Get Paid So Little?
Authors: Lee Joohee 
Published: October 2023

Abstract
Korea is a country with extremely long working hours and severe gender inequality in the labor market. Based on twenty-nine in-depth interviews with Korean women care workers, this study investigates key mechanisms that reproduce unpaid and unrecognized shadow labor in paid care services. Accordingly, it argues that the presumption that it is mostly Korean men who suffer from working long hours is incorrect. Women workers work long hours, and they often do so without compensation for overtime. They also engage in labor that is not included in their original job description. The Korean labor market supplies an unlimited number of women for cheap labor in the care service sector, meaning the government can depend heavily on private organizations and businesses to meet increasing care needs among the population. Because women care workers could not specify an employer who is responsible for their wages and working conditions, they could not see themselves as employees with basic labor rights. Instead, they take the familiar roles of dutiful daughters and caring mothers, consenting to the very situation that makes them susceptible to severe wage penalties and unrecognized and unappreciated long working hours.
Education, Employment, Family Formation Behaviors, and the Gender Health Gap: A Cross-National Comparison of Korea, the United States, and Finland
Authors: Woo Hyeyoung , Wilkinson Lindsey , Yoon Soo-Yeon 
Published: October 2023

Abstract
Despite improvements in the social status of women in recent decades, women still tend to report lower levels of health compared to men. This study examines the role of individual factors (i.e., education, employment, and family formation behaviors) and aggregate factors (i.e., gender context, work cultures, and work-family policy) in the association between gender and health using the cases of Korea, the United States, and Finland. The study’s results indicate that women experience lower levels of health than men in Korea and the United States, especially among younger adults, even after accounting for education, employment, and family status. In Finland, however, women do not have lower levels of health than men. Moreover, among older individuals, Finnish women exhibit a health advantage relative to Finnish men. The findings indicate that traditional gender role expectations, long hours at work, and inadequate work-family balance largely account for gender disparities in health in Korea and the United States. Gender egalitarianism at work, reduced work hours, and more family friendly work policies should help reduce such disparities.
The lymphatic system favours survival of a unique T. brucei population
Authors: Machado Henrique , Temudo António , Niz Mariana De 
Published: October 2023

ABSTRACT
Trypanosoma brucei colonise and multiply in the blood vasculature, as well as in various organs of the host's body. Lymph nodes have been previously shown to harbour large numbers of parasites, and the lymphatic system has been proposed as a key site that allows T. brucei distribution through, and colonization of the mammalian body. However, visualization of host-pathogen interactions in the lymphatic system has never captured dynamic events with high spatial and temporal resolution throughout infection. In our work, we used a mixture of tools including intravital microscopy and ex vivo imaging to study T. brucei distribution in 20 sets of lymph nodes. We demonstrate that lymph node colonization by T. brucei is different across lymph node sets, with the most heavily colonised being the draining lymph nodes of main tissue reservoirs: the gonadal white adipose tissue and pancreas. Moreover, we show that the lymphatic vasculature is a pivotal site for parasite dispersal, and altering this colonization by blocking LYVE-1 is detrimental for parasite survival. Additionally, parasites within the lymphatic vasculature have unique morphological and behavioural characteristics, different to those found in the blood, demonstrating that across both types of vasculature, these environments are physically separated. Finally, we demonstrate that the lymph nodes and the lymphatic vasculature undergo significant alterations during T. brucei infection, resulting in oedema throughout the host's body.
Quantitative assessment of condylar bone resorption using fused CBCT images: differentiating and diagnosing three distinct groups based on volume and thickness decrease
Authors: Feng Ji-ling , Ma Ruo-han , Sun Li-li , Zhao Jun-ru , Zhao Yan-ping , Li Gang 
Published: October 2023

Objectives
To investigate the accuracy of fused CBCT images in diagnosing three distinct groups of bone changes characterized by volume and thickness decrease in patients with temporomandibular joint osteoarthrosis (TMJ OA) during follow-up.

Methods
In this retrospective study, 109 patients (176 TMJs) with TMJ OA were included. Two consecutive CBCT images for the same patient were registered and fused. Then, three image sets were established: without fusion, fused 2D image, and fused 3D image. Three residents randomly and independently evaluated whether there was condylar resorption with the three image sets respectively. The samples diagnosed as condylar resorption by the expert panel were divided into three subgroups according to the volume and thickness decrease calculated after segmentation. The inter- and intraobserver agreement, receiver operating characteristic (ROC), and area under the curve (AUC) evaluated the diagnostic capability for different subgroups.

Results
For the volume decrease more than 50 mm3 and thickness decrease more than 1 mm groups, the AUC values for fused image sets were higher than those without fusion (p &lt; 0.01). For the volume decrease within 50 mm3 and thickness decrease within 1 mm groups, the AUC values for fused 2D image sets were higher than the image sets without fusion (p &lt; 0.05), but there was no significant difference between the fused 3D image sets and the image sets without fusion (p = 0.48 for volume decrease, p = 0.37 for thickness decrease).

Conclusions
The fused images can improve the diagnostic accuracy and repeatability for the samples with at least 50 mm3 volume decrease or 1 mm thickness decrease compared with the image groups without fusion.
Folkloric orality in contemporary culture
Authors: Hajduk-Nijakowska Janina 
Published: October 2023

Accepting the anthropological perspective of analysing oral folklore, understood as a part of culture – any culture – requires a redefinition of the notion of orality in contemporary culture. Orality does not mean solely oral direct transmission of texts; it also reveals a way in which human beings operate in their world, as well as the manner of its cognition formed by folk-type thinking. A message may also be transmitted in the form of visual or electronic communication. Analysing contemporary folkloric texts from the anthropological perspective requires changing the existing method of acquiring research material. This includes primarily the situation in which the given text is realized. The cultural context is especially significant in analysing Internet-based form of folkloric communication, where it is necessary to take the role of virtual community into account. By penetrating the Internet, the content which until then functioned outside it is subjected to changes resulting from the Internet-related inspiration. It therefore co-creates e-folklore, the analysis of which must take the exceptional activity of Internet users into consideration. The process of contemporary cultural socialisation has been in a nearly natural way enriched by folkloric orality.
Motyw kreacji przez rysunek w folklorze polskim i wschodniosłowiańskim
Authors: Gołębiowska-Suchorska Agnieszka 
Published: October 2023

W artykule podjęta została próba egzemplifikacji ludowego motywu ożywiania przedmiotów oraz ludzi przez rysunek. Taki akt kreacji nie został dotychczas sklasyfikowany jako odrębny motyw ustnego folkloru, dlatego przyjęto termin roboczy „motyw kreacji przez rysunek”. Przykłady realizacji motywu odnaleziono w gatunkach polskiego, ukraińskiego i rosyjskiego folkloru (legendy ajtiologiczne, legendy bohaterskie, bajki magiczne, bajki humorystyczne), polskiego e-folkloru (demotywatory) oraz w polskiej i rosyjskiej literaturze i kinematografii dla dzieci. Motyw kreacji przez rysunek jest obecny w tekstach kultury o różnej intencji nadawczej – informacyjnej (legendy ajtiologiczne, legendy o bohaterach), ludycznej (humoreski, demotywatory), kompensacyjnej (bajka magiczna), dydaktycznej (literatura i kinematografia dziecięca) i nostalgicznej (demotywatory). Trwałość motywu kreacji przez rysunek w różnych tekstach kultury wynika z uniwersalnej tęsknoty człowieka za możliwością szybkiej realizacji pragnień i poprawy własnego życia lub świata.
Functions of a Fairy Tale in the Auschwitz Camp Memories of Zofia Posmysz
Authors: Smyk Katarzyna 
Published: October 2023

The article gives a multifaceted interpretation of the functions of a concentration camp fairy tale from the perspective of folklore studies (i.e. its socio-integrative, aesthetic, didactic/educational, compensatory/cathartic and trauma management functions) and literary studies (strategies of women’s writing about the Holocaust and the war, and the camp testimony). The author analyses the novel Wakacje nad Adriatykiem (1970) and an extended interview Królestwo za mgłą (2017) by Zofia Posmysz, an inmate of Auschwitz-Birkenau, Ravensbrück and Neustadt-Glewe, who stylised her camp memories as a traditional folk tale, thus commemorating the fairy tales told by her camp friend Zofia Jachimczak, who did not survive Auschwitz. The author comes to the conclusion that a concentration camp fairy tale seems to be a complete genre and a comprehensive structure of meaning that makes it possible to express the inexpressible.
Activating transrelational ethnography. Interweaves of the field in the process of energy transition
Authors: Majbroda Katarzyna 
Published: October 2023

The article presents one of the strands of empirical research on the energy transition process conducted by an anthropologist in Upper Lusatia, in the Bogatynia municipality, in the area around the Turów mining and power complex. The perspective of transrelational ethnography makes it possible to weave together the various elements of this process and look at its changing environmental/economic, political and socio-cultural conditions. The text shows some of the many interweaves uncovered in the field, in the decarbonisation process, seen in the perspective of transrelational ethnography. It focuses on the ambiguities in the worlds of the region’s residents as brought to light in the study. The author draws attention to epistemological traps, such as the category of conflict, that await the anthropologist in a field that faces an uncertain post-coal future. Also, the author stresses the lack of preparedness of the volatile, conceptually unclosed field and its unstable, complex, assemblage architecture.