bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cariprazine Augmentation in Treatment-Resistant Bipolar Depression:
Data from a Retrospective Observational Study
Authors: Teobaldi Elena , Pessina Enrico , Martini Azzurra , Cattaneo Carlo Ignazio , De Berardis Domenico , Martiadis Vassilis , Maina Giuseppe , Rosso Gianluca 
Published: January 2024

Background:
Treatment-resistant bipolar depression is one of the leading problems in psychiatry
with serious consequences on patients functioning, quality of life and resource utilization.
Despite this, there is a lack of consensus on diagnostic criteria and treatment algorithms.

Objective:
The objective of the present study is to assess the acute effectiveness and tolerability of
cariprazine in the management of treatment resistant bipolar depression.

Methods:
This is a four weeks retrospective multicentric observational study on patients with treatment
resistant bipolar depression receiving cariprazine in augmentation to the current treatment.
Cariprazine dosage changed during the follow-up period according to clinical judgment. Since data
followed a non-normal distribution, non-parametric tests were used to pursue the analysis. The effectiveness
of cariprazine was assessed through the mean change in Hamilton Depression rating scale
(HAM-D) scores from baseline to endpoint. For missing values, a “Last Observation Carried Forward”
approach was applied

Results:
Fifty-one patients were enrolled. Four patients (7.8%) discontinued cariprazine mainly due to
adverse events. Mean cariprazine dose was 1.7 mg/day. The mean HAM-D score decreased significantly
from baseline (T0) to week 4 (T4) at each evaluation point. Fourty-five one percent of the patients
benefited of cariprazine add-on strategy: 23.5% achieved a clinical response and 21.6% were
remitters. Among the completers, 70.6% experienced at least one adverse event. All side effects were
mild to moderate.

Conclusion:
Cariprazine seems to be an effective and well tolerated option in the management of
patients with treatment resistant bipolar depression.
Австралийский вектор монгольской миграции: основные параметры и тенденции
Authors:   Institute for Mongolian, Buddhist and Tibetan Studies, Siberian Branch of the RAS (6, Sakhyanova St., 670047 Ulan-Ude, Russian Federation), Aktamov Innokentii G. , Vinokurova Anna V. , Orolmaa Munkhbat ,   Banzarov Buryat State University (24A, Smolin St., 670000 Ulan-Ude, Russian Federation),   Far Eastern Federal University (10, Ajax Bay, Russky Island, 690922 Vladivostok, Russian Federation),   National University of Mongolia (1, Ikh Surguuli St., 14201 Ulaanbaatar, Mongolia)
Published: January 2024

Goals. The article aims to characterize some key aspects of present-day migration from Mongolia to Australia. Materials and methods. The study employs a comprehensive methodology to analyze international and national statistics data from the United Nations, UNESCO, Governments of Australia and Mongolia, etc. It also involves discourse analyses of Russian-, Mongolian- and English-language print and online publications dealing with the migration of Mongolian citizens to Australia. Survey methods have proved as instrumental, e. g., expert surveys, informal interviews, and questionnaires. Field research was conducted in the summer of 2022. Results. The study reveals key characteristic features of Mongolian migration to Australia. Firstly, Mongolian migrants in Australia are a fastest growing group of foreign migrants. Currently, Australia is becoming an increasingly popular labor (third place after the Republic of Korea and the USA) and educational (fourth place after China, Korea and Japan) destination for Mongolian citizens. Secondly, the main driving force of labor migration from Mongolia to Australia is the economic motive; however, non-financial factors play an equally important role — low population density, similar to landscapes, high living standards and quality of life, favorable migration situation in the host society. Thirdly, educational migration from Mongolia to Australia, as well as labor migration, has a high potential, is associated with further employment prospects and professional self-realization for Mongolian citizens both at home and in the destination country. Labor and educational migration is stimulated by active special government programs within operating Australia-Mongolia agreements both in industrial/economic (primarily in mining) and humanitarian spheres (various scholarships, academic mobility). The countries anticipate an expansion of economic, cultural and educational cooperation, which shall make it possible to implement mutually beneficial projects.
INVESTIGATION OF THE EFFECT OF MESH SIZE AND FRACTION VOLUME ON BENDING STRENGTH CHARACTERISTICS OF GEOPOLYMER COMPOSITE
Authors: Afandi Ridwan , Munadi Muhammad , Paundra Fajar , Hastuti Sri , Nurdin Akhmad 
Published: January 2024

Composite material is a material consisting of two or more type materials that have different properties, by combining macroscopically, and good interfacial bonds from one material to another. Currently, polymer composite materials are widely applied in the land, sea, and air transportation industries, moreover polymer composites with fire resistance properties have been developed with the addition of geopolymer that has the advantage of producing high performance. This study aims to determine the effect of mesh size and volume fraction of lightweight brick powder on flexural strength. The benefits of this research directly increase the economic value of lightweight brick waste and produce a tough advanced material at a low cost. The composite filling material used lightweight brick waste and sieved using a sieve with a level of 50, 100, 150, and 200 at a volume fraction of 45%, and a volume fraction of 0%, 15%, 30%, 45%, and 60% at a mesh 200. While the composite matrix used the thermoset polymer Ripoxy R-804. Based the result, addition of lightweight brick powder with variations in particle size of the lightweight brick powder and volume fraction showed a decrease in flexural strength resistance compared to those without lightweight brick powder.
MANAGEMEN FISIOTERAPI PADA KASUS LESI SARAF OKULOMOTOR UNILATERAL: A CASE REPORT
Authors: Maranti Zemba Riski , Perdana Suryo Saputra 
Published: January 2024

ABSTRAK
Pendahuluan: Lesi saraf okulomotor atau neuropati okulomotor adalah kondisi mata akibat kerusakan saraf kranial ketiga atau cabangnya yang mana dapat menyebabkan penurunan kekuatan otot yang diinervasi yang menghasilkan gerakan bola mata yang berkurang ke beberapa arah dan ketidakmampuan kelopak mata untuk membuka (ptosis). Fisioterapi adalah salah satu profesi klinis yang bertugas membantu individu pulih dari gangguan saraf dengan menggunakan metode berbasis neuroplastisitas. Tujuan: Untuk mengetahui efektivitas pemberian program fisioterapi berupa gabungan dari beberapa intervensi seperti pemberian infrared, Electrical Stimulation menggunakan arus faradik, dan eye exercise pada pasien dengan kondisi lesi saraf okulomotor unilateral. Metode: Penelitian ini menggunakan Single-subject research yang dilakukan kepada seorang wanita berusia 50 tahun dengan diagnosa lesi saraf okulomotor unilateral. Hasil : Baseline dan evaluasi dilakukan dengan menggunakan instrument pengukuran mistar untuk mengukur celah kelopak mata dan pursuit test untuk mengetahui kemampuan pergerakan bola mata. Kesimpulan: Terdapat peningkatan yang positif pada kemampuan kelopak mata dan kemampuan pergerakan bola mata setelah diberikan intervensi fisioterapi selama 4 minggu.
Kata kunci : lesi saraf okulomotor, ptosis, electrical stimulation, eye exercise.

ABSTRACT
Introduction: An oculomotor nerve lesion or oculomotor neuropathy is an eye condition resulting from damage to the third cranial nerve or its branches which can cause a decrease in the strength of the innervated muscles resulting in reduced eyeball movement in several directions and inability of the eyelids to open (ptosis). Physiotherapy is a clinical profession whose job is to help individuals recover from nervous disorders by using methods based on neuroplasticity.Objective: to determine the effectiveness of a physiotherapy program in the form of a combination of several interventions such as giving infrared, Electrical Stimulation using faradic currents, and eye exercise in patients with unilateral oculomotor nerve lesions.Method: This study used a single-subject research conducted on a 50 year old woman with a diagnosis of unilateral oculomotor nerve lesion. Results: Baseline and evaluation were carried out using a ruler measuring instrument to measure the eyelid gap and a pursuit test to determine the ability to move of the eyeball Conclusion: There was a positive increase in the ability of the eyelids and the ability to move the eyeball after being given physiotherapy intervention for 4 weeks.
Keyword : oculomotor nerve, ptosis, electrical stimulation, eye exercise.
PERBEDAAN PENGARUH MYOFASCIAL RELEASE DENGAN MUSCLE ENERGY TECHNIQUE TERHADAP PENURUNAN DISABILITAS MECHANICAL NECK PAIN PADA GURU SMA
Authors: Hasannah Hanni Nur , Agustina Dwi , Kurniawan Ganesa Pupu Dinda 
Published: January 2024

Pendahuluan: Mechanical neck pain merupakan tipe nyeri leher yang disebabkan oleh pembebanan secara mekanik akibat postur yang tidak tepat atau adanya ketegangan di area otot leher. Beberapa permasalahan pada mechanical neck pain salah satunya adalah disabilitas gerak pada sendi leher. Intervensi fisioterapi dapat menurunkan disabilitas leher tersebut dengan pemberian myofascial release dan muscle energy technique. Metode: Penelitian yang dilaksanakan di SMA Islam di Jakarta Barat ini menggunakan desain quasy eksperimen. Besar sampel sebanyak 28 orang yang terbagi dalam 2 kelompok dipilih dengan purposive sampling. Kelompok pertama diberikan intervensi myofascial release dan yang kedua muscle energy technique masing masing dengan frekuensi 3 kali seminggu selama 4 minggu. Variabel bebas disabilitas diukur Neck Disability Index (NDI). Analisa data meliputi univariate, bivariat dengan paired sample t-test dan independent t=tes. Hasil: Intervensi myofascial release menurunkan disabilitas leher dari 18,57 menjadi 17,78 dan p value 0,3. Intervensi muscle energy technique dapat menurunkan disabilitas mechanical neck pain dari 18,71 menjadi 15,14 dan p value 0,000. Hasil uji independent test adalah 0,002. Kesimpulan: Intervensi myofascial release tidak efektif dalam menurunkan disabilitas mechanical neck pain. Sedangkan intervensi muscle energy technique lebih efektif dalam menurunkan disabilitas mechanical neck pain dibandingkan dengan myofascial release. Untuk mencegah terjadinya keluhan nyeri pada mechanical neck pain terulang, sebaiknya muscle energy technique dapat tetap dilakukan secara mandiri di rumah.
Generic Graphical User Interface for CBIR Framework
Authors: Ali Layak 
Published: January 2024

AbstractContent-based image retrieval system (CBIR) is a well-known and widely used system for image retrieval. Most of the current CBIR systems are either command-based or specific to applications. However, due to the availability of a good computing facility, a graphical way of retrieving images may prove to be very useful for both industrial and research purposes. This paper proposes a generic and user-friendly graphical user interface (GUI) for CBIR framework. With the proposed GUI, any user with or without knowledge of CBIR can operate and retrieve images of their choice among a huge number of images. The GUI gives a vast range of facilities for selecting options. The proposed GUI is implemented and verified on a well-known image database.
A Rigid Image Registration by Combined Local Features and Genetic Algorithms
Authors: Meskine Fatiha , Mezouar Oussama 
Published: January 2024

AbstractImage registration is an essential pre-processing step required for many image processing applications such as medical imaging and computer vision. The aim is to geometrically align two or more images of the same scene by establishing a mapping that relies on each point from one image to its corresponding point of another image. Scale invariant feature transform (SIFT) and speeded up robust features (SURF) are well-liked local features descriptors that have been extensively utilised for feature-based image registration due to their inherent properties such as invariance, changes in illumination, and noise. Moreover, the task of registration can be viewed as an optimization problem that can be solved by applying genetic algorithms (GAs). This paper presents an efficient feature image registration method based on combined local features and GAs. Firstly, the procedure consists of extracting the local features from the images by combining SIFT and SURF algorithms and matching them to refine the feature set data. Therefore, an adaptive GA based on fitness sharing and elitism techniques is employed to find the optimal rigid transformation parameters that best align the feature points by minimizing a distance metric. The suggested method is applied for registering medical images and the obtained results are significant compared to other feature-based approaches with reasonable computation time.
Conceptual Framework for Assessing the Impact of Implementing an Integrated Territorial Approach for Regional Development
Authors: Stoyanova Mariela 
Published: January 2024

Abstract
The Cohesion policy of the European Union is the basis of the principle concept of functioning in the Community. In this regard, achieving its main goals is of particular importance. In the context of overcoming the main weaknesses before achieving cohesion goals in the Community, the new paradigm of regional development based on integrated and strategic development initiatives and clearly defined competitiveness factors is becoming increasingly popular. The new approach is oriented towards compensatory actions in narrowly defined and nationally significant areas to discover and use the potential of the regions to achieve the “critical mass” necessary for further development. It is for this reason that the new approach for integrated regional development was already adopted in the previous planning period 2014-2020 in the majority of member states.
This article aims to define the conceptual framework for assessing the impact of integrated territorial investments. The methods used are content analysis of documents and GAP analysis, following standard inductive and deductive logical connections. As a result, some key challenges to implementing the integrated territorial approach in Bulgaria have been outlined. The structure of the publication contains a literature review on the topic, a methodological justification of the tools used, and a presentation of the main results and discussion questions.
Coordination of Communication Budget with Marketing Objectives in the Banking Sector
Authors: Manea Miruna Ioana , Marcu Laura 
Published: January 2024

Abstract
The paper discusses the problem of establishing the communication budget in one of the most active sectors regarding marketing communication, the banking one. Firstly, we highlight the particularities of communication in the banking sector, based on the results presented in the specialized literature. The functions of marketing communication and the communication process are applied to the specifics of banking institutions and the main communication models that banks can use are indicated, depending on the objectives pursued. Also, the main means of banking communication and how they can be associated with marketing objectives are synthesized. Based on diversification of the means of communication, we emphasized the attention that banks must pay to integrated marketing communication, a concept whose application contributes to the efficiency of communication at the level of each targeted category. In the second part, we addressed the methods that banking institutions can apply to size their communication budget and how the efficiency of its allocation can be evaluated. The data presented are based on the documentary study and the realization of a case study applied to the banking field in Romania. Although the results show that the banking sector in Romania is one of the sectors with the highest advertising expenses, the trends evidenced in terms of banking communication at a global level cannot be ignored, so Romanian banks will have to adapt their communication strategy and, along with this, how the communication budget is allocated.
Social Innovation – a Powerful Statement from Companies for a Sustainable Environment
Authors: Barb Roxana-Maria 
Published: January 2024

Abstract
Today’s environmental challenges are catching the attention of many companies to seek innovative solutions to solve the roots of these problems through strong partnerships with governmental entities and other organizations. Social innovation is a topic that can leverage new ideas and practices to overcome current societal and environmental issues fostering sustainability. The purpose of this paper is to highlight the importance of social innovation by presenting a pragmatic and comparative study case analysis of two companies that successfully implemented social innovation in their business model. Social innovation combined with open innovation are great catalysts in solving societal and environmental problems and creating shared value and having an impact on business strategy. These two organizations strive to create change and develop a learning environment to surpass all risks and challenges to solve environmental problems. The paper will provide evidence on the importance of closing partnerships in the social innovation process and how collaboration helps in generating shared value.
Climate Change and Population Growth Rate: any Implications for Economic Growth in Nigeria?
Authors: Kareem Rasaki Olufemi , Isiaq Temitope Shukrat , Fabunmi Boluwatife Esther , Taiwo Abdulqodir Babatunde 
Published: January 2024

Abstract
The study was on Nigeria’s CC, PGR, and economic growth (1986-2021). Secondary data collected from the Central Bank of Nigeria Statistical Bulletin, World Bank, WDI, and Nigerian Meteorological Agency (NIMET) were analyzed using unit root test, Auto-regressive distributed lag model (ARDL) for climate change since variables were of I(1) & I(0) as there was no co-integration. In contrast, the Error Correction Model (ECM) was used for population growth rate as variables were of I(1) and I(0), and there was co-integration. The GC test was adopted to determine the causal relationship among variables. The results showed that the coefficient values of lag one and two of LNRGDP had a significant relation with economic growth at both 10% and 1%, respectively, while lag three period of CAE was significant at a 5% level of probability. The study showed that birth growth rate and net migration positively and negatively impacted economic growth. It also showed unidirectional causality between crude death rate and economic growth and life expectancy at birth with economic growth. The study, therefore, recommends that the government invest in critical policies (real sectors of the economy) for economic growth and research the area of clean energy and eco-friendly approaches and population management with awareness campaigns that can ensure sustainable economic development.
HUBUNGAN KOMORBIDITAS DENGAN GAMBARAN CT SCAN TORAKS PADA PASIEN TERKONFIRMASI COVID-19
Authors: Suminto Silvia , Asriyani Sri , Latief Nikmatia , Alfian Andi , Djaharuddin Irawaty , Murtala Bachtiar 
Published: January 2024

Penelitian ini bertujuan untuk mengetahui hubungan komorbiditas dengan gambaran CT scan toraks pada pasien terkonfirmasi COVID-19. Penelitian ini dilaksanakan di Departemen Radiologi RSUP dr. Wahidin Sudirohusodo Makassar dengan jumlah sampel sebanyak 192 pasien terkonfirmasi COVID-19. Analisis karakteristik gambaran CT scan toraks pasien dilakukan pada lung dan mediastinal window untuk melihat gambaran Groundglass opacity (GGO),konsolidasi, crazy paving, halo sign, air bronchogram sign (ABS), fibrosis, nodul, limfadenopati mediastinum, dan efusi pleura. Perbedaan proporsi gambaran CT scan berdasarkan komorbiditas diuji dengan chi-square.
Hasil penelitian menunjukkan terdapat hubungan yang signifikan antara pasien dengan riwayat komorbiditas terhadap gambaran GGO, konsolidasi, crazy paving, nodul, fibrosis, efusi (semua nilai p<0,05). Terdapat hubungan yang signifikan pada pasien dengan riwayat hipertensi dengan gambaran GGO, dan crazy paving (keduanya p<0,05), riwayat diabetes mellitus dengan gambaran konsolidasi (p<0,05), riwayat CKD dengan gambaran efusi pleura (p<0,05), riwayat keganasan dengan gambaran nodul (p<0,05), riwayat CAD dengan gambaran crazy paving (p<0,05), dan riwayat tuberkulosis dengan gambaran fibrosis, tree in bud dan nodul (p<0,05).
THE RELATION BETWEEN THE NEUTROFIL LYMPHOCYTE RATIO (NLR) AND THE DEGREE OF DENGUE HEMORRHAGIC FEVER IN THE INPATIENT INSTALLATION OF ARI CANTI HOSPITAL FOR THE PERIOD OF APRIL 2022 – MAY 2023
Authors: Mahayanti Kadek Seri , Suardamana Ketut 
Published: January 2024

Dengue Hemorrhagic Fever is caused by dengue virus infection which can cause death and cause an outbreak. Neutrophil lymphocyte ratio (NLR) is one of the cheap laboratory parameters and can predict plasma leakage in the critical period of dengue hemorrhagic fever. This study aims to determine the profile of dengue hemorrhagic fever patients and the relationship between the neutrophil lymphocyte ratio and the degree of dengue hemorrhagic fever in patients treated at Ari Canti Hospital for the period April 2022 – May 2023. This research is a retrospective analytical study with a cross-sectional approach using secondary data from archives at the Ari Canti Hospital Inpatient Installation for the period April 2022-May 2023. Data collection in the form of gender, age, neutrophil lymphocyte ratio and degree of dengue hemorrhagic fever was carried out using the convenient purposive sampling method. This study shows that the highest age group is the 26-35-year age group 35.7%, the highest gender is male 55.3% with cases of dengue hemorrhagic fever without shock 89.2% and a neutrophil lymphocyte ratio (NLR) of >2 as much as 64.2%. The result of Mann Whitney non-parametric test, showed that p value <0.0001. There is a significant relationship between NLR and the degree of dengue hemorrhagic fever in patients hospitalized at Ari Canti Hospital in April 2022, May 2023.
Keywords : dengue virus., dengue hemorrhagic fever., hospitalization., neutrophil lymphocyte ratio