bluuebunny/crossref_metadata_2025_split huggingface dataset:
Goldenseal (Hydrastis canadensis L.) Extracts Inhibit the Growth of Fungal Isolates Associated with American Ginseng (Panax quinquefolius L.)
Authors: Gao Ying , Swiggart Ethan , Wolkiewicz Kaela , Liyanapathiranage Prabha , Baysal-Gurel Fulya , Avin Farhat A. , Lopez Eleanor F. P. , Jordan Rebecca T. , Kellogg Joshua , Burkhart Eric P. 
Published: January 2024

American ginseng, a highly valuable crop in North America, is susceptible to various diseases caused by fungal pathogens, including Alternaria spp., Fusarium spp., and Pestalotiopsis spp. The development of alternative control strategies that use botanicals to control fungal pathogens in American ginseng is desired as it provides multiple benefits. In this study, we isolated and identified three fungal isolates, Alternaria panax, Fusarium sporotrichioides, and Pestalotiopsis nanjingensis, from diseased American ginseng plants. Ethanolic and aqueous extracts from the roots and leaves of goldenseal were prepared, and the major alkaloid constituents were assessed via liquid chromatography–mass spectrometry (LC–MS). Next, the antifungal effects of goldenseal extracts were tested against these three fungal pathogens. Goldenseal root ethanolic extracts exhibited the most potent inhibition against fungal growth, while goldenseal root aqueous extracts and leaf ethanolic extracts showed only moderate inhibition. At 2% (m/v) concentration, goldenseal root ethanolic extracts showed an inhibition rate of 86.0%, 94.9%, and 39.1% against A. panax, F. sporotrichioides, and P. nanjingensis, respectively. The effect of goldenseal root ethanolic extracts on the mycelial morphology of fungal isolates was studied via scanning electron microscopy (SEM). The mycelia of the pathogens treated with the goldenseal root ethanolic extract displayed considerable morphological alterations. This study suggests that goldenseal extracts have the potential to be used as a botanical fungicide to control plant fungal diseases caused by A. panax, F. sporotrichioides, or P. nanjingensis.
DETERMINANTS OF GOING CONCERN AUDIT OPINION
Authors: Nafsiyyah Zakiyyatun Dea , Prameswari Desty Villa , Sartika Eka , Umyana Ayu 
Published: January 2024

Abstract: This study was conducted in order to determine the impact of audit quality, total asset turnover, company size, growth opportunity, DER, DAR, and previous year's audit opinion on audit opinion regarding business continuity in food and beverage subsector companies located on the IDX in the period 2020 to 2022. Financial statements are secondary data used in research with purposive sampling in determining and based on predetermined characteristics there are 78 companies. Quantitative becomes a research model using logistic regression so as to obtain results where previous period Audit Opinions have an impact on Going Concern Audit Opinions, while Audit Quality, Total Asset Turnover, Company Size, Company Growth, Debt To Equity, Debt To Asset have no impact on Going Concern Audit Opinions in food and beverage subsector manufacturing companies.
Keywords: Debt To Asset, Debt To Equity, Audit Quality, Going Concern Audit Opinion, Previous Year Audit Opinion, Total Asset Turnover, Company Size
التّوازي الفونيمي في قصيدة بلقيس لنزار قبّاني
Authors: جقامة نضال موسى مرزوق 
Published: January 2024

الأهداف: يهدف البحث إلى دراسة التّوازي الفونيمي في قصيدة بلقيس كأنموذج من شعر نزار قبّاني، بُغية كشف الجماليّات الأسلوبيّة والأبعاد الدّلالية التي قامت عليها، مع إيضاح مفهوم التّوازي الفونيمي الصوتي، وبيان أهمّيته، والعناصر المشكّلة لبنيته، بوصفه ظاهرة فنيّة موسيقيّة دلاليّة تُضيء النّص جمالًا وإيحاءً.
المنهجية: اعتمد البحث المنهج الوصفي التحليلي مستعينًا بالقراءة الإحصائيّة والاستدلاليّة المبنيّة على قراءات رقميّة لقصيدة بلقيس لنزار قباني، وبيان نِسب التوزيع الفونيمي بدقّة لربطها بالدلالات المضمونيّة والإيحائية والنفسية عند الشاعر.
النتائج: وظّف الشاعرَ التوازي الفونيمي ورسم مرصوفة فسيفسائية، تناسب من خلالها الإيقاع الموسيقي بهذا التشكيل الصوتي مع الدلالة والحالة النفسية التي عاشت في قلب الشاعر ووجدانه وقلمه، وتآزرت لتشكّل مفردات وجُمل تناغمت مع المعنى المراد. وقد أبْدَع نزار قبّاني في نسج توازياتٍ فونيميّةٍ صوتيّةٍ في مرثيّتِه، زادت القيمة الجمالية ورفدت الإيقاع الصوتي المتميّز ببعديه الحزين والثائر، حيث استطاع أن يُوصله إلى مَسامِع المتلقي وإحْسَاسِه، لينعكس ذلك على التشكيل الدَّلالي الذي قد يجول بخاطرهِ وفكره عند القراءة.
الخلاصة: التّوازي الفونيمي في قصيدة بلقيس قيمة فنّية كشفت عن لغة إبداعيّة خلّاقة لدى الشّاعر، حملت في بنيتها العمق الدّلالي والتّناغم الإيقاعي، مما حقّق لمُبدعها التفرّد والتّميز. توصي الدراسة بضرورة التحليل الإحصائي من خلال ابتكار برامج حسابيّة عبر الكمبيوتر، للمساهمة في تسهيل فهم التوزيع الصوتي في القصيدة ابتداءً من الفونيم، واستنباط دلالات التوزيع الصوتي والقيم الجمالية والنتائج المترتبة عليه..
Semiotics... Introduction to "Signs Computing"
Authors: Eddahbi Mohamed 
Published: January 2024

Objectives: Figuring out the importance of the semiotic perspective in computing signs. in addition to setting up databases that can be invested in designing flexible applications of the automated diacritization, automated translation.
Methods: It is designed as follows a theoretical part dedicated to evoking some of the manifestations of the flexibility of semiotics, as well as mentioning some studies that have taken semiotics as their general framework for analysis, such as kinaesthetics and computational semiotics. An applied part in which a model based on semiotic concepts is presented to set up a synthetic database for the Arabic language, the automated diacritization as a model.
Results: With its theoretical concepts and applied procedures, semiotics can serve as a basic entry for signs computing.
Conclusions: The study recommends researchers to evoking semiotics during the automated processing of the Arabic language and its culture, both theoretical and applied, to overcome the inadequacies of the Arabic language applications and software.
The Psychological Impact of Physical Assault by Husbands and its Role in Instigating Wives’ Suicide: A Comparative Study
Authors: Abuameerh Oraib Ali 
Published: January 2024

Objectives: This study investigates differences in terms of the psychological problems and suicidal ideation between women who were victims of physical assault by their husbands and those who were not subject to it in Jordan.
Methods: The study sample consists of 102 women; 51 women were subject to abuse by their husbands whereas 51 women were not. The study uses seven sub-scales of the second issue of the computerized, multi-aspect personality test, namely depression, psychopathic deviation, psychasthenia, anxiety, Kane’s post-traumatic disorder, Schlinger’s post-traumatic disorder, and suicidal thoughts.
Results: The results of the current study show that there are statistically significant differences between women who were hit by their husbands and those who were not, favoring women who were physically assaulted. Differences between the two types of women apply to all aspects of the study (depression, suicidal thoughts, psychopathic deviation, psychasthenia, Kane’s post-traumatic disorder, Schlinger’s post-traumatic disorder, and anxiety).
Conclusions: The study reveals that physical assault by husbands constitutes an important motive for wives’ suicide. Despite the fact that many Arab and non-Arab studies deal with issues of abuse and violence against women, the current study is unique in the sense that it is the only one in the region that examines the impact of this physical assault on the psyche of women, showing that the differences are in favor of women who were victims of their husbands’ abuse in comparison to women who were not.
Clinicopathological Features and Prognosis of Primary Breast Sarcoma: A Single Centre Retrospective Study
Authors: Ullah Naqib , Sameen Bin Naeem  , Ali Jhatial Mussadique , Abdul Wahab  , Rabeea Shahid  , Manzoor Khan  , Asim Shazia , Siddiqui Neelam 
Published: January 2024

Objective: This study aims to describe clinicopathological characteristics and outcomes of primary breast sarcoma (PBS) and the relevance of clinical and pathological characteristics with the outcomes.
Methodology:
Study Design: Retrospective longitudinal study
Place and duration of study: Department of Medical Oncology Shaukat Khanum Memorial Cancer Hospital and Research Centre Lahore from January 1995 to August 2021.
Patients aged 18 years and older were included in the study. Individuals with primary or secondary angiosarcoma or cystosarcoma phyllodes were not included. The hospital information system was used for collecting data, and data was collected for 27 patients meeting inclusion study criteria.
Results: Twenty-seven patients were treated with surgery, seven out of 27 patients (25.90%) received adjuvant chemotherapy and 2 patients (7.40%) received chemotherapy on a palliative intent. The remaining (66.70%, n=18) did not receive chemotherapy. Twenty-four out of 27 patients (88.90%) received radiation therapy; intent was adjuvant in the entire cohort. Median PFS was 18 months with 74.01% of patients having no progression at their last follow-up. The median OS was 23 months. Adjuvant radiotherapy was associated with a significant overall survival benefit (P-value: 0.05). Adjuvant chemotherapy was not associated with a significant survival benefit (P-value: 0.5). Age, tumor size, and disease status (localized disease) conferred a non-significant trend towards a better outcome.
Conclusion: Adjuvant radiotherapy is the only factor that affects the outcomes of this disease. Further multicentred and preferably prospective studies with a larger number of patients are required to define disease characteristics and patient outcomes of primary breast sarcoma in Pakistan.
Keywords: clinical characteristics, outcomes, prognosis, primary breast sarcoma (PBS)
Classification of direct optical signal inputs by Ag2S island network reservoir
Authors: Matsuo Risa , Hasegawa Tsuyoshi 
Published: January 2024

Abstract
We have reported that a physical reservoir with a silver sulfide island network can classify simple patterns of an irradiated light without converting it to a voltage signal input. In this study, we conducted experiments to verify whether the detection of dynamical change in an irradiating light, e.g., moving in a reservoir layer, can be available. We also investigated the possibility that the reservoir could detect a position of light exposure, in addition to the dependence on the wavelength and the exposure time. The technique was applied to a task of whether character-shaped light patterns could be recognized even if the irradiated position was changed.
Research on tactile sensation by physical reservoir computing with a robot arm and a Ag2S reservoir
Authors: Yoshimura Kaiki , Hasegawa Tsuyoshi 
Published: January 2024

Abstract
In recent years, physical reservoir computing has attracted much attention because of its low computational cost and low power consumption. In terms of social implementation of artificial intelligence, physical reservoir has a potential to meet the request, such as the need for AI robots to process information related to tactile sensation. It has been reported that a Ag2S polycrystalline thin film retains short-term memory and non-linearity when used as a physical reservoir. In this study, we applied the technique to tactile sensation by combining with a pressure sensor attached to a robot arm. In the object grasping task, a Ag2S physical reservoir enabled the objective recognition with the accuracy of 81.3%, although the task failed with linear regression of the direct output from the pressure sensor. We also demonstrate the potential of the system to detect anomalies in object grabbing.
Analysis of tunneling probability in heavily doped 4H-SiC Schottky barrier diodes based on complex band structure considering barrier potential
Authors: Murakami Yutoku , Nagamizo Sachika , Tanaka Hajime , Mori Nobuya 
Published: January 2024

Abstract
The tunneling probability in heavily doped 4H-SiC Schottky barrier diodes (SBDs) is analyzed based on the empirical pseudopotential method (EPM). A method of calculating the tunneling probability within the WKB approximation using the EPM electronic states of bulk 4H-SiC has been reported. In the present study, to investigate the validity of this method, the tunneling probability is calculated by connecting the incident, transmitted, and reflected wavefunctions considering the barrier potential of a SBD instead of using the WKB approximation. Comparing the calculated results with and without the WKB approximation, the difference is found to be rather small. This suggests that we can safely use the WKB approximation with the bulk electronic states, which are obtained without considering the barrier potential, when calculating the tunneling current in the heavily doped 4H-SiC SBDs.
The Quaternions and Representing Methods
Authors: Wala Abdul Razzak Mohamed  
Published: January 2024

In this paper I deal with quaternions history which were discovered by William Rowan Hamilton in 1843.
Also I take some definitions and the basic properties of quaternions.
My basic aim is how to representing quaternions as matrices. There are at least two ways of the representing of matrices, the first way is used 2×2 complex matrices and the second one is used 4×4 real matrices.
I can able to generalize the first way by using n×n complex matrices that n is even.
Effectiveness of Single-Tablet Combination Therapy in Improving Adherence and Persistence and the Relation to Clinical and Economic Outcomes
Authors: Paoli Carly J. , Linder Jörg , Gurjar Khushboo , Thakur Deepika , Wyckmans Julie , Grieve Stacy 
Published: January 2024

Background: Single-tablet combination therapies (STCTs) combine multiple drugs into one formulation, making drug administration more convenient for patients. STCTs were developed to address concerns with treatment adherence and persistence, but the impact of STCT use is not fully understood across indications. Objectives: We conducted a systematic literature review (SLR) to examine STCT-associated outcomes across 4 evidence domains: clinical trials, real-world evidence (RWE), health-related quality of life (HRQoL) studies, and economic evaluations. Methods: Four SLRs were conducted across the aforementioned domains. Included studies compared STCTs as well as fixed-dose combinations ([FDCs] of non-tablet formulations) with the equivalent active compounds and doses in loose-dose combinations (LDCs). Original research articles were included; case reports, case series, and non-English-language sources were excluded. Databases searched included EconLit, Embase, and Ovid MEDLINE® ALL. Two independent reviewers assessed relevant studies and extracted data. Conflicts were resolved with a third reviewer or consensus-based discussion. Results: In all, 109 studies were identified; 27 studies were identified in more than one SLR. Treatment adherence was significantly higher in patients receiving FDCs vs LDCs in 12 of 13 RWE studies and 3 of 13 clinical trials. All 18 RWE studies reported higher persistence with FDCs. In RWE studies examining clinical outcomes (n = 17), 14 reported positive findings with FDCs, including a reduced need for add-on medication, blood pressure control, and improved hemoglobin A1C. HRQoL studies generally reported numerical improvements with STCTs or similarities between STCTs and LDCs. Economic outcomes favored STCT use. All 6 cost-effectiveness or cost-utility analyses found FDCs were less expensive and more efficacious than LDCs. Four budget impact models found that STCTs were associated with cost savings. Medical costs and healthcare resource use were generally lower with FDCs than with LDCs. Discussion: Evidence from RWE and economic studies strongly favored STCT use, while clinical trials and HRQoL studies primarily reported similarity between STCTs and LDCs. This may be due to clinical trial procedures aimed at maximizing adherence and HRQoL measures that are not designed to evaluate drug administration. Conclusions: Our findings highlight the value of STCTs for improving patient adherence, persistence, and clinical outcomes while also offering economic advantages.
Optimization of Digitization-Based Ant Sugar Micro, Small and Medium Enterprises (UMKM) in Cimarias Village
Authors: Putra Hendri Darma , Chandra Wijaya  , Ishak Abdul Rojak  , Muhammad Irfan Febrianto  , Siti Maspupah  , Rika Amalia  
Published: January 2024

Angkeub Hamlet, located in Cimarias Village, Pamulihan Subdistrict, Sumedang Regency, has great UMKM potential in palm sugar production. However, Angkeub Hamlet has challenges in developing its economy, namely the lack of community understanding of digital business. This research aims to open the insights of training participants about product diversification from palm sugar. This activity was carried out with a qualitative method in the form of direct discussions with residents, namely palm sugar craftsmen. The results of this thematic KKN program are that the community gained a new understanding of palm sugar cultivation, bookkeeping, product legality, and the operation of platforms for digital marketing through social media and e-commerce, and became a fostered village of Universitas Islam Nusantara. The conclusion of this program has contributed to the livelihood of the community by providing them with new income opportunities. Increased added value of printed palm sugar products into ant sugar. After participating in this program, the craftsmen can technically know the process of making ant sugar and digital marketing, but assistance is still needed to escort them to the production scale and legality. Therefore, the prospect of long-term cooperation output is in the form of an Islamic Nusantara University Assisted Village.
DETECÇÃO PRECOCE DE LESÕES BUCAIS E DOENÇAS INFECCIOSAS: O PAPEL DO DENTISTA NO PROGRAMA SAÚDE DA FAMÍLIA
Authors: Araújo Aline Prado Langame , Santos Marcos Antônio Lima dos , Farias Anderson Fernandes de Carvalho , Capelario Elenice de Fatima Souza , Marceliano-Alves Marília Fagury Videira , Feijão Lucas Evangelista Alves , Souza Júlia de Oliveira , Abreu Tamaia Batista , Paiva Geilson Mendes de , Fernandes Jefferson Douglas Lima 
Published: January 2024

Introdução: A detecção precoce de lesões bucais e doenças infecciosas é fundamental para o sucesso do Programa Saúde da Família. O dentista desempenha um papel crucial ao realizar exames regulares e educar a comunidade sobre a importância da saúde bucal, contribuindo para a prevenção e tratamento eficaz dessas condições. Objetivo: Analisar qual o papel do dentista na detecção precoce de lesões bucais e doenças infecciosas, no contexto do programa saúde da família. Metodologia: Estudo do tipo revisão de literatura, conduzida entre setembro de 2023 e janeiro de 2024, nas bases da LILACS, PUBMED e SCIELO, com os descritores: “Programa saúde da família”; “Dentista”; “Lesões”; “Doenças Infecciosas”. Os critérios de inclusão foram: disponibilidade gratuita, acesso integral, redigidos em português ou inglês, publicados nos últimos 10 anos (2014-2024), já os de exclusão, duplicatas. monografias e dissertações. Ao final, apenas 13 estudos foram selecionados para a amostra. Resultados e Discussões: A atuação proativa do dentista é crucial para impulsionar a promoção abrangente da saúde bucal no Programa Saúde da Família. Além de identificar precocemente lesões e doenças, o profissional estabelece uma conexão próxima com a comunidade, oferecendo orientações e intervenções oportunas, gerando um impacto positivo duradouro na saúde bucal da população atendida. Conclusão: Em conclusão, a atuação do dentista no PSF se destaca pela realização de exames clínicos periódicos, permitindo a identificação precoce de lesões bucais, como por exemplo, abusos e violências. Além disso, desempenha um papel vital na detecção precoce de condições como infecções periodontais e lesões ulcerativas.
Analisis Faktor-Faktor yang Memengaruhi Kepatuhan Minum Obat pada Penderita DM Tipe 2 di Wilayah Kerja Puskesmas Muarasoma Tahun 2021
Authors: Dalimunthe Puput Novianty , Sipayung Novreka Pratiwi , Sitanggang Ervina Julien , Zaluchu Ristarin Paskarina 
Published: January 2024

Abstract
Background : Type 2 DM is DM with hyperglycemia due to a combination of insulin action resistance, insulin secretion and excessive or inadequate glucagon secretion. High adherence to medication is one of the factors that determine the success of the DM type 2 control process.
Objective : This study aimed to analyze the factors that influence adherence to taking antidiabetic drugs in the Muarasoma Health Center Work Area in 2021.
Methods: This study is an analytical study using a cross-sectional approach which was conducted on 77 patientswith type 2 DM according to the inclusion and exclusion criteria in the working area of the Muarasoma HealthCenter. Knowledge level, medication adherence and family support were measured using the Diabetes Knowledge Quiestionnaire (DKQ-24), Morisky Medication Adherence Scale (MMAS-8) and the Hensarling Diabetes Family Support (HDFS) which have been validated.
Results: The factors influencing medication adherence in patients with type 2 DM were gender with p value = 0,002), education level with p value = 0,007, income with p value = 0,015, level of knowledge with p value =0,047, and family support with p value = 0,043). Factors that are not associated with medication adherence in patients with type 2 DM were DM duration with p value = 0,059 and drug regimen with p value = 0,056
Conclusion: The factors that influence medication adherence in patients with type 2 DM at the Muarasoma Health Center are gender, level of education, level of knowledge, income, and family support.
Perbandingan Aktivitas Antibakteri Berbagai Produk Hand Sanitizer terhadap Escherichia coli dan Staphylococcus aureus In Vitro
Authors: Simaremare Ade Pryta Romanauli 
Published: January 2024

Background: Hand hygiene is very important because human hands are often contaminated with microorganisms, so that it becomes an intermediary for the entry of disease-causing microorganisms into the body, especially Escherichia coli and Staphylococcus aureus. The use of hand sanitizer has shown an increase in society. Hand sanitizers are available with various types of packaging, dosage forms, variations in the composition of active ingredients and their carriers at quite competitive prices.Objective: To determine the antibacterial effect of various hand sanitizers available in the market and their comparison with antiseptic handwash soap.Methods: Antibacterial effectiveness test using the Kirby Bauer method by measuring the diameter of the clear zone produced on Muller Hinton media by diffusion discs tested with four hand sanitizer products available in the market compared with antiseptic hand soap as positive control and akuades as negative control.Results: Various hand sanitizer products containing 70% alcohol showed moderate to strong inhibition against E. coli and S.aureus. Analysis of differences in the activities of various hand sanitizer products using the KruskalWallis non-parametric method showed a difference with p= 0.003 against E. coli and p=0.002 against S.aureus. Alcohol denatures bacterial proteins so that it interferes with the metabolic processes of bacterial cells which causes bacterial cell death.Conclusion: Hand sanitizer is effectively used to inhibit the growth of E. coli and S.aureus bacteria.