bluuebunny/crossref_metadata_2025_split huggingface dataset:
B - 101 Comparing Working Memory and Verbal Comprehension between Adults with Learning Disabilities in Math Versus Reading
Authors: Rodriguez Czarinah Micah , Tsay Clay , Abinader Melodie L , Golden Charles J 
Published: October 2023

Abstract

Objective
This study uses the Wechsler Adult Intelligence Scale-Fourth Edition (WAIS-IV) to compare working memory and verbal comprehension of adults with learning disorders in math (LD-M) and learning disorders in reading (LD-R).

Method
The data were chosen from a de-identified database in the Neuropsychology Assessment Center (NAC) at Nova Southeastern University. The sample chosen consisted of adults with LD-M (N = 37) and LD-R (N = 35). The participants were mostly female (70.8%). The racial background consisted of African Americans (15.3%), Caucasians (48.6%), Latino-Hispanics (25.0%), and Others (11.1%). The mean education of the sample was 13.5 years and the mean age was 30.6. All of the participants were administered the WAIS-IV to evaluate verbal comprehension and working memory.

Results
An independent samples t-test with the Bonferroni correction revealed that LD-M (M = 85) scored significantly lower in working memory (p = 0.03) than LD-R (M = 91) with medium effect size (d = 0.52). However, there were no significant differences in verbal comprehension between LD-M and LD-R.

Conclusion
There were significant differences in working memory between LD-M and LD-R but not in verbal comprehension. LD-R performed better than LD-M in working memory, but LD-M did not perform better in verbal comprehension. The results suggest that although LD-R might have an advantage over LD-M in terms of working memory, LD-M might not necessarily have an advantage over LD-R in terms of verbal comprehension. Keywords: working memory, adults, verbal comprehension, Specific Learning Disorder.
B - 107 Exploratory Analysis of the Relationship between Health Anxiety (HA) and Neuropsychological Performance in a Validity Controlled Sample of Patients with Post-Acute Sequelae of COVID-19 (PASC)
Authors: Turchmanovych-Hienkel Nataliya , Oh Alison , Basurto Karen , VanLandingham Hannah , Jennette Kyle 
Published: October 2023

Abstract

Objective
Since the emergence of COVID-19, research has consistently indicated cognitive difficulties as a primary complaint after infection (Altuna et al., 2021). It is unclear to what extent these cognitive deficits may be attributable to, or exacerbated by, health anxiety (HA) (Venkataramani et al., 2022). This study explored the relationship between HA and cognition in a performance validity controlled sample of patients with PASC complaints.

Methods
Participants included patients referred for a focused neuropsychological evaluation for persistent cognitive complaints after COVID infection (N = 19). Participants were excluded for Test of Memory Malingering scores below standard cutoff. The sample mean age was 43 years (SD = 12.9), 57.9% were female, and 47.4% were from minority racial/ethnic groups. HA was assessed using the Short Health Anxiety Inventory (SHAI). Cognitive abilities were measured using the Wechsler Adult Intelligence Scale–IV (WAIS-IV: Processing Speed Index [PSI]; Letter–Number Sequencing [LNS]) and Trail Making Test Part-A (TMT-A). Regression analyses were conducted to assess the extent to which HA predicts cognitive performance.

Results
The SHAI main subscale significantly predicted TMT-A [β = −3.93, p &lt; 0.01] and WAIS-IV PSI [β = −4.60, p = 0.04]. The SHAI negative consequences subscale significantly predicted TMT-A [β = −4.64, p = 0.04] and WAIS-IV LNS [β = 0.49, p = 0.048].

Conclusions
Findings suggest that general HA predicted PSI, while fear of negative health outcomes predicted LNS. Basic attention abilities were predicted by global HA. Future studies will benefit from evaluating the moderating effect of HA on the relationship between subjective symptom severity and cognition.
B - 109 Neurorehabilitation in Pediatric Acquired Brain Injuries: the Need for More Evidence Based Research
Authors: Yancey Erin , Williams Julie 
Published: October 2023

Abstract

Objective
Many children after sustaining an acquired brain injury (ABI) have noticeable changes in cognitive functioning (CF) making transitioning back to school difficult (Vanderlind et al., 2022). Neurorehabilitation helping to alleviate difficulties in CF are crucial to helping children succeed in school, however there is limited research on the effectiveness of neurorehabilitation in pediatric ABI’s (Stark et al., 2020). This poster aims to highlight the current literature surrounding neurorehabilitation in pediatric ABI and recommendations for future research.

Data Selection
Literature was obtained using PsychInfo and PubMed and searching keywords such as pediatric ABI, neurorehabilitation, and CF. Selected articles from 2000–2022 were reviewed and main findings were consolidated.

Data Synthesis
Cognitive domains affected after an ABI include memory, executive functioning, and attention (Stark et al., 2020). Programs like AIM, NeuroPage, Captains Log, Cognitive Remediation Program, and MITII have been studied to test their effectiveness in alleviating these cognitive difficulties in pediatric ABI’s (Linden et al., 2018, Wilson et al., 2009, Piovesana et al., 2017, Treble-Barna et al., 2016). According to the literature the only program that showed an improvement in CF was NeuroPage (Wilson et al., 2009).

Conclusions
Research conducted on the efficacy of neurorehabilitation programs for memory, executive functioning, and attention in pediatric ABI’s has shown mixed results. Due to the likelihood of children having difficulties in academic performance after an ABI, it is crucial that psychologists focus on research addressing the efficacy of interventions for these cognitive domains. Future research should focus on creating interventions that successfully target and improve CF in pediatric ABI.
B - 111 The Role of Education, and Advocacy in Repeat Neuropsychological Evaluations of a Spanish Speaking Woman with Anti-LG-1 Encephalitis
Authors: Viruet- Sánchez Esteban , McGinley John , Bronshteyn Diana , Facchini Ronda , Facchini Ronda , Stimmel Marnina , Weiss Erica F 
Published: October 2023

Abstract

Objective
Anti-leucine-rich glioma-inactivated 1 limbic encephalitis (LGI1-LE) is a rare diagnosis but the second most common autoimmune encephalitis. While it has a growing body of neuropsychological literature, there is limited awareness by the lay public about this condition. As with all complex neurological conditions, caregiver/family understanding of the disorder and engagement in treatment is important for optimal recovery and dyad wellbeing. We present the case of a caregiver and patient dyad with confirmed LGI1-LE/ Voltage-Gated Potassium Channel antibodies seen for repeat neuropsychological evaluations to demonstrate the importance of education, advocacy, and multidisciplinary involvement as part of the neuropsychological assessment process.

Method
Repeat neuropsychological evaluations of a 72-year-old Spanish-speaking woman with limited formal education and complex medical history, including past strokes and recent autoimmune encephalitis.

Results
Initial evaluation revealed marked behavioral and cognitive fluctuations/variability with familial frustration secondary to poor understanding by caregiver until neuropsychological feedback session. Repeat evaluation was delayed four weeks due to caregiver factors but demonstrated improvement in global cognition and overall functioning. Follow up, six months later, demonstrated significant cognitive decline and new motoric symptoms with further difficulty coordinating appointments by the caregiver. In addition to assistance with medical management, neuropsychological involvement led to connection to case management, home evaluation, concrete solutions for food insecurity, and cognitive evaluation for the caregiver.

Conclusions
This case adds to LG1-LE literature and demonstrates the importance of neuropsychology not only for disease tracking/ management but also as an important tool for advocacy and patient/caregiver education, specifically in culturally and educationally diverse populations with complex medical conditions.
B - 112 Navigating your Survivorship Journey: Leveraging the Biopsychosocial Model in Conceptualization and Continued Care for Brain Tumor Survivors
Authors: Feeney Kathleen E , Naidoo Reshma B , Rivero-Conil Sara , Khatib Ziad A 
Published: October 2023

Abstract

Objective
A neuropsychological assessment provides a limited snapshot of functioning based on the aperture of the lens selected. The journey of cancer survivorship is complex, requiring navigation of the social and cultural milieu (Carpentieri et al., 2003; Hoffmann-Lamplmair et al., 2023; Hörnquist et al., 2015; Otth et al., 2021). A biopsychosocial model provides a holistic approach to understanding survivorship (Walsh et al., 2016). The case conceptualization of a 17-year-old non-Hispanic Asian male posterior fossa tumor survivor, 13 years post-treatment, will be discussed.

Method
Longitudinal neuropsychological assessment data [2011–2023] were compared to identify neurocognitive late effects associated with chemoradiotherapy. Parent- and self-reports of adaptive, behavioral, and emotional functioning were obtained. The impact of reduced verbal communication and overreliance on parent-reports are compared to self-report and clinical assessment data.

Results
Neurocognitive late effects (executive functioning, processing speed, verbal fluency) were prominent in 2023. Although two extended episodes of atypical behavior emerged in the past year, parent- and self-reports did not indicate any elevated concerns for emotional dysregulation. However, social desirability bias, tendency to underreport emotional symptoms, and an internal negative self-view were significant on self-reports.

Conclusions
Although some changes in functioning could be explained by late effects of treatment (Schreiber et al., 2017), others may be better accounted for by social and cultural factors that impact the conceptualization and acceptance of emotional symptoms (Kim et al., 2013). Acknowledging and disclosing emotional difficulties (Liw et al., 2022), as well as seeking mental health care (Abe-Kim et al., 2007), is culturally mediated and can be both protective and/or limiting.
H - 01 “¿Cómo qué, ¿Cómo qué? ¿Cómo qué?” Single-Language Echolalia in a Bilingual Female with Progressive Supranuclear Palsy: a Case Report
Authors: Abdullah Lubnaa , Blanco-Elorrieta Esti , Valdez David 
Published: October 2023

Abstract

Objective
Bilingualism has been associated during brain development with differences in cortical thickness and increased cortical connectivity in areas involved in language production and comprehension (Pilatsikas, et al., 2020). However, much less is known about the role of bilingualism and neurodegeneration. The following case illustrates a neuropsychological profile of a 78-year-old, Mexican American, bilingual female, who, at the 80th minute of her psychiatric interview, displays echolalia, but only in response to Spanish speech. To date, this is the only case report demonstrating single-language echolalia in a bilingual female with progressive non-fluent aphasia (PNFA) in progressive supranuclear palsy (PSP).

Methods
The Assessment follows a flexible battery approach.

Results
The patient is diagnosed with PSP with PNFA, as well as depression and anxiety.

Conclusion
Echolalia that manifests in a single language disproves theories suggesting that it is a purely auditory phenomenon and places the focus of the disorder at the phonological retrieval stage. Single-language echolalia in a bilingual individual suggests that either a) language control mechanisms can be selectively impaired, such that only one language is successfully monitored to avoid repeated productions or b) representation of each language in the bi/multilingual brain could be fully independent of each other. Last, there is a question as to what the exact step of neurodegeneration could lead to this phenomenon. In all, a detailed analysis of this and other cases could shed light on what patterns of language loss could be expected in multilingual individuals and what language background and neurodegenerative factors contribute to such pattern during aging.
H - 03 Modifiable Risk Factors Associated with Cognitive Decline in Hispanic Elders: a Literature Review
Authors: Alcina Jorge , Guevara Linda Rios , Duarte Andres , Villafana Mei-Ling , Gonzalez Dayron , Haddock Yanelee Perez 
Published: October 2023

Abstract

Objective
This systematic literature review aimed to explore the association of modifiable risk factors and cognitive decline in Hispanic elders.

Data Selection
Peer-reviewed empirical studies published between 2013 and 2023, in English, were searched using databases Google Scholar, Medline, PsychINFO, and PsychARTICLES. Keywords entailed cognitive decline, dementia, elderly, Hispanic, and Latino/a/x. The initial search yielded 21 articles, of which eight were retained. Excluded from this study were literature reviews, meta-analyses, case studies, and any non-peer-reviewed articles.

Data Synthesis
All articles retained identified modifiable risk factors associated with cognitive decline and dementia in Hispanics. Two articles solely contained samples of Hispanics without other ethnic groups, while six comprised combined samples. Most prevalent modifiable risk factors included low levels of education, low socioeconomic status (SES), lack of access to healthcare, unmarried status, unhealthy lifestyle habits (e.g., poor diet, smoking, physical inactivity), midlife obesity, diabetes, hypertension, depression, and hearing loss. These factors conveyed different levels of risk for Hispanic individuals.

Conclusions
The literature on modifiable risk factors linked to cognitive decline in Hispanics paralleled similar literature on other ethnic groups. For Hispanics and other racial/ethnic minorities, factors like low educational level and low SES (closely related to cognitive impairment) warrant modification at local, state, and national levels. All factors identified represent targets of intervention which, long-term, will likely be related to increased duration and quality of life, and reduced medical costs. Limitations of the present study include scarce empirical studies on the topic, as well as lack of delineation of regional and subgroup differences among Hispanic populations.
H - 05 Non-Pharmacological Treatment for Older Adults with Mild Cognitive Impairment: Expanding Diversity into Clinical Practice and Research
Authors: Azar Martina , Arias Franchesca , Stelmokas Julija 
Published: October 2023

Abstract

Objective
Numerous non-pharmacological treatments (NPT) have been developed for older adults with mild cognitive impairment (MCI) (Bahar-Fuchs, Mowszowski, Lautenschlager, & Cox, 2021). Two forms of NPTs, namely cognitive rehabilitation (CR) and cognitive training (CT) may demonstrate cognitive benefit, but there remain significant methodological challenges in the field (Barban et al., 2016; McPhee, Downey & Stough, 2019; Sherman et al., 2020). One such limitation is the contribution of cultural and demographic factors to study outcome heterogeneity. Our goal was to highlight examples of select culturally informed NPTs and provide recommendations to expand diversity into clinical practice and research.

Data Selection
Discussed results and limitations of recent meta-analyses and systematic reviews that focused on NPTs for MCI in older adults. We completed a review of culturally informed NPTs from the past two years. Clinician experiences informed the inclusion of additional diversity variables (e.g., methodological, demographic, social, systemic) that could be integrated into clinical practice and research.

Data Synthesis
There is a paucity of research considering cultural and demographic factors when delivering NPTs. Results of culturally informed CR or CT highlighted themes in the adaptation of language, cognition, function, diet, and physical activity. Additional provider, patient, and systemic factors can be considered to promote diversity, equity, and inclusion (DEI).

Conclusions
Culturally informed NPTs are understudied. Practical recommendations for US-based clinicians and researchers are provided that could increase access/recruitment, retention, and outcome in CT and CR for diverse populations.
H - 06 Associations between Non-verbal Reasoning Abilities and Brain Pathology in a Colombian Cohort with Autosomal Dominant Alzheimer’s Disease
Authors: Badillo Cabrera Alex L , Baena Ana , Martinez Jairo , Bocanegra Yamile , Castelar Clara Vila , Lopera Francisco , Quiroz Yakeel 
Published: October 2023

Abstract

Objective
Declines in non-verbal reasoning abilities have been linked to Alzheimer’s disease (ad) progression. Individuals with autosomal dominant ad (ADAD) are genetically determined to develop early-onset dementia. We examined the relation between non-verbal reasoning abilities and brain pathology in a Colombian cohort with ADAD due to the Presenilin-1 (PSEN1) E280A mutation.

Method
A total of 25 carriers of the PSEN1 E280A mutation (16 cognitively-unimpaired carriers [x- age = 35.25 +/− 4.04]; 9 with mildly impaired (age = 45.56 +/− 2.60), and 27 non-carriers (age = 36.11 +/− 5.59) were included. A summary non-verbal reasoning score was calculated from performance on the Judgment of Line Orientation and the Spanish WAIS-IV Matrix Reasoning and Visual Puzzles subtests. Participants also completed the Mini-mental State Examination (MMSE) and underwent amyloid and tau PET imaging. Mann–Whitney U test and education-adjusted Spearman partial correlations were used to examine group differences and associations between pathology levels and non-verbal reasoning.

Results
Compared to carriers, non-carriers had higher MMSE and non-verbal reasoning scores (p = 0.006). In carriers only, lower non-verbal reasoning was associated with greater mean cortical amyloid (r = −0.427, p = 0.037) and greater precuneus tau (r = −0.516, p = 0.010). No significant associations were observed after excluding the impaired carriers from the analyses.

Conclusion
Our findings suggest that changes in non-verbal reasoning abilities are evident in early symptomatic ADAD stages and are related to ad brain pathology. Future longitudinal work is needed to characterize the progression of non-verbal reasoning deficits in ADAD. Future research should also examine performance between older adults and people at risk for sporadic ad.
H - 09 Neighborhood Disadvantage, Education Quality, and Cognitive Function in Community-Dwelling Black and White Older Adults with Metabolic Syndrome
Authors: Hunter Jennifer M , Grant Jeremy G , Perez-Lao Ambar , Adrien Tamare , Adler Tessa , Ali Hana , Levy Shellie-Anne 
Published: October 2023

Abstract

Objective
Low education quality is a risk factor for late-life cognitive decline and is often associated with living in a socioeconomically disadvantaged neighborhood, particularly among racialized older adults. This study examined the relationships among neighborhood disadvantage, education quality, and cognitive function from a larger pilot study of older adults at risk for cognitive decline due to metabolic syndrome.

Participants and Methods
Participants were 46 older adults (64.0% women, 39.1% Black, mean age = 72.4 years) who completed a neuropsychological assessment, including measures of speeded word generation (NACC Verbal Fluency Test) and problem-solving (WCST-64). Education quality was estimated via word recognition (WRAT-IV Word Reading). Neighborhood disadvantage was examined using the Area Deprivation Index.

Results
Greater neighborhood disadvantage was associated with fewer years of education, lower education quality, and lower performance on word generation and problem-solving. Mediation analyses indicated that the direct effect of neighborhood disadvantage on word generation was not significant, whereas the indirect effect mediated by education quality was significant (b = −0.180, t = −2.684). The total effect of neighborhood disadvantage on problem solving was significant (b = −0.134, p = 0.027), but the direct and indirect effects were not.

Conclusions
Neighborhood disadvantage was selectively associated with cognitive measures heavily influenced by executive function, namely using an efficient word generation strategy, and incorporating feedback to guide problem-solving. However, the effect of neighborhood disadvantage on cognition may be best explained by its association with reduced education quality. Neighborhood disadvantage can be a modifiable risk factor through improved education quality to mitigate risk of cognitive decline.
H - 13 Examining the Cultural Sensitivity of a Novel Neuropsychological Assessment in Distinguishing between Cognitively Unimpaired (CU) and Amnestic Mild Cognitive Impairment (aMCI) in Hispanic Older Adults
Authors: Sosa Jaylene , Bosworth Brooke , Ramirez Sofia , Crenshaw Kirsten , Ortega Alexandra , Hincapie Diana , Zheng Diane , Neer Emory , Cid Rosie Curiel , Loewenstein David 
Published: October 2023

Abstract

Objective
Common neuropsychological measures are not sensitive in capturing early cognitive changes associated with prodromal Alzheimer’s Disease (ad) and vary across cultural groups. The Cognitive Stress Test (CST) is a novel assessment with high levels of sensitivity and specificity that measures maximum learning, proactive interference (PSI), retroactive interference, and the ability to recover from PSI (FrPSI). Authors evaluated the utility of the CST in distinguishing between aMCI versus CU Hispanic older adults.

Method
18 aMCI and 15 CU older adults (mean age = 73.06; SD = 7.94, 42.4% male) were compared using the CST. Participants were categorized into the aforementioned groups using the Clinical Dementia Rating and results of neuropsychological evaluation. CST was not used in categorization to avoid circularity. CST includes the presentation of 18 target words from two semantically related wordlists (occupations, household items, and transportation) and assesses FrPSI over repeated trials.

Results
Data was analyzed utilizing an ROC curve to measure differences between CU and aMCI. The ROC curve demonstrated an area under the curve of 0.92, indicating that PSI was significant in differentiating participants. Findings suggest that PSI may be an early feature of aMCI groups who are at higher risk of progression to clinical ad.

Conclusions
The CST was deemed to be an effective and culturally sensitive memory measurement tool among Hispanic older adults. In future studies, this paradigm may be particularly useful in deconstructing cognitive processes that can be compared to structural and functional MRI, amyloid and tau PET imaging, and emerging plasma biomarkers of ad.