bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gender and magnetic resonance imaging classification-related differences in clinical and biochemical characteristics of Cushing's disease: a single-centre study
Authors: Chen Yufan , Mei Xiaobo , Jian Fangfang , Ma Qinyun , Chen Xiao , Bian Liuguan , Sun Qingfang 
Published: January 2024

Background
Cushing's disease (CD) presents a remarkable preponderance in female gender, and a significant minority of patients with CD presented with negative magnetic resonance imaging (MRI) findings. The aim of this study was to evaluate gender-related and MRI classification-related differences in clinical and biochemical characteristics of CD.

Methods
We retrospectively studied 169 patients with CD, comprising 132 females and 37 males, and 33 patients had no visible adenoma on MRI.

Results
We observed that male and MRI-positive patients presented with high adrenocorticotropic hormone (ACTH) values (P <0.05). Female patients presented with higher prevalence of hirsutism and hyperpigmentation and lower prevalence of purple striae (P <0.05). The prevalence of buffalo-hump and hypertension was greater in MRI-negative patients (P <0.05). In addition, male patients with CD presented at a younger age compared with females (P <0.05). Patients with fatigue and hypokalaemia presented significantly higher urinary-free cortisol, ACTH and cortisol levels compared with patients without these symptoms (P <0.05). The prevalence of LH reduction, hyper total cholesterol (TC) and hyper low-density lipoprotein was more frequent in MRI-positive patients (P <0.05). Hyper-TC levels and PRL reduction were more frequent in males (P <0.05). T3, T4 and FT3 levels negatively correlated with age at diagnosis (r=-0.310, P <0.01; r=-0.191, P <0.05; r=-0.216, P <0.05). T3, T4, FT3 and FT4 levels significantly negatively correlated with 8-am plasma cortisol levels (r=-0.328, P <0.01; r=-0.195, P <0.05; r=-0.333, P <0.01; r=-0.180, P <0.05). Females presented higher total protein level (P <0.01) and lower blood urea nitrogen and serum creatinine levels (P <0.01), compared with male patients.

Conclusions
Carefulness and caution are required in all patients with CD, because of the complexity of clinical and biochemical characteristics in CD patients of different gender and MRI classification, particularly male patients and MRI-negative patients.
Data analysis of 36 cases with intraductal papillary mucinous neoplasm of the pancreas for their clinicopathological features, diagnosis, and treatment
Authors: Yuan Chunhui , Xiu Dianrong , Tao Ming , Ma Zhaolai , Jiang Bin , Li Zhifei , Li Lei , Wang Liang , Wang Hangyan , Zhang Tonglin 
Published: January 2024

Background
Intraductal papillary mucinous neoplasm (IPMN) is a rare pancreatic cystic neoplasm, accounting for 1% of all exocrine pancreatic neoplasms. This study aimed to summarize the clinicopathological and biological behaviors, as well as the experience in diagnosis and treatment of IPMN.

Methods
Clinicopathological data were collected from 36 cases with IPMN who were treated in Department of General Surgery, Peking University Third Hospital from May 2001 to July 2011.

Results
The 36 cases of IPMN patients included 27 males and 9 females (M:F=3:1). The age of patients ranged from 52 to 78 years, with an average of 67.3 years. Regarding tumor location, 20 tumors were located in pancreatic head, 3 in pancreatic neck, 10 in pancreatic body and tail, and 3 in the whole pancreas. All the 36 cases underwent surgical treatment, with 13 cases of pancreaticoduodenectomy, 3 cases of middle pancreatectomy, 7 cases of tumor resection plus pancreaticojejunostomy, 3 cases of distal pancreatectomy, 7 cases of distal pancreatectomy plus spleen resection, and 3 cases of total pancreaticoduodenectomy. Of the 36 patients, 9 patients underwent the operations under laparoscopy. The 36 cases included main duct type (14 cases, 38.9%), branch duct type (10 cases, 27.7%), and mixed duct type (12 cases, 33.3%). Pathologically, of the 36 cases, there were 7 IPMN adenomas, 11 borderline IPMNs, 6 IPMN with carcinomas in situ, and 12 IPMNs with invasive carcinomas. All the 36 cases were followed up. During an average of 42 months follow-up period (26-129 months), no recurrence occurred.

Conclusions
IPMN, which primarily occurs in male, is a low-grade malignancy which may involve any part of the pancreas, with specific clinicopathological features. IPMN is a different malignancy type from pancreatic ductal carcinoma. Imaging and laboratory examination are helpful for the diagnosis and differential diagnosis. The prediction of invasive IPMN is still difficult. Surgical resection is recommended as the first choice of treatment. Aggressive and proper operation procedure produces better prognosis. Long-term follow-up is necessary for patients after operation. Laparoscopic distal pancreatectomy is a feasible and safe procedure for the indicated patients.
X-Ray Polarization of the Eastern Lobe of SS 433
Authors: Kaaret Philip , Ferrazzoli Riccardo , Silvestri Stefano , Negro Michela , Manfreda Alberto , Wu Kinwah , Costa Enrico , Soffitta Paolo , Safi-Harb Samar , Poutanen Juri , Veledina Alexandra , Di Marco Alessandro , Slane Patrick , Bianchi Stefano , Ingram Adam , Romani Roger W. , Cibrario Nicolò , Mac Intyre Brydyn , Mikus̆incová Romana , Ratheesh Ajay , Steiner James F. , Svoboda Jiri , Tugliani Stefano , Agudo Iván , Antonelli Lucio A. , Bachetti Matteo , Baldini Luca , Baumgartner Wayne H. , Bellazzini Ronaldo , Bongiorno Stephen D. , Bonino Raffaella , Brez Alessandro , Bucciantini Niccolò , Capitanio Fiamma , Castellano Simone , Cavazzuti Elisabetta , Chen Chien-Ting , Ciprini Stefano , De Rosa Alessandra , Del Monte Ettore , Di Gesu Laura , Di Lalla Niccolò , Donnarumma Immacolata , Doroshenko Victor , Dovčiak Michal , Ehlert Steven R. , Enoto Teruaki , Evangelista Yuri , Fabiani Sergio , García Javier A. , Gunji Shuichi , Hayashida Kiyoshi , Heyl Jeremy , Iwakiri Wataru , Jorstad Svetlana G. , Karas Vladimir , Kislat Fabian , Kitaguchi Takao , Kolodziejczak Jeffery J. , Krawczynski Henric , La Monaca Fabio , Latronico Luca , Liodakis Ioannis , Maldera Simone , Marin Frédéric , Marinucci Andrea , Marscher Alan P. , Marshall Herman L. , Massaro Francesco , Matt Giorgio , Mitsuishi Ikuyuki , Mizuno Tsunefumi , Muleri Fabio , Ng Chi-Yung , O’Dell Stephen L. , Omodei Nicola , Oppedisano Chiara , Papitto Alessandro , Pavlov George G. , Peirson Abel L. , Perri Matteo , Pesce-Rollins Melissa , Petrucci Pierre-Olivier , Pilia Maura , Possenti Andrea , Puccetti Simonetta , Ramsey Brian D. , Rankin John , Roberts Oliver J. , Sgrò Carmelo , Spandre Gloria , Swartz Douglas A. , Tamagawa Toru , Tavecchio Fabrizio , Taverna Roberto , Tawara Yuzuru , Tennant Allyn F. , Thomas Nicholas E. , Tombesi Francesco , Trois Alessio , Tsygankov Sergey S. , Turolla Roberto , Vink Jacco , Weisskopf Martin C. , Xie Fei , Zane Silvia 
Published: January 2024

Abstract
How astrophysical systems translate the kinetic energy of bulk motion into the acceleration of particles to very high energies is a pressing question. SS 433 is a microquasar that emits TeV γ-rays indicating the presence of high-energy particles. A region of hard X-ray emission in the eastern lobe of SS 433 was recently identified as an acceleration site. We observed this region with the Imaging X-ray Polarimetry Explorer and measured a polarization degree in the range 38%–77%. The high polarization degree indicates the magnetic field has a well-ordered component if the X-rays are due to synchrotron emission. The polarization angle is in the range −12° to +10° (east of north), which indicates that the magnetic field is parallel to the jet. Magnetic fields parallel to the bulk flow have also been found in supernova remnants and the jets of powerful radio galaxies. This may be caused by interaction of the flow with the ambient medium.
Social Media in Nursing Education: A Systematic Review
Authors: Sarginson Dawn , Cecilia Wendler M. 
Published: January 2024

Background:
Although social media is emerging as an educational tool in health care professions, little is known about which social media platforms support nursing education in different situations.

Method:
This systematic review examined and ranked the level of evidence that supports social media use in nursing education.

Results:
A total of 19 studies published between 2017 and 2022 were evaluated and described in an evidence table. Results revealed social media is used in a variety of settings and in different ways, including providing enhanced learning for hands-on skills, supporting course activities such as journal clubs, and creating a sense of community and belongingness.

Conclusion:

Social media in health care education can address asynchronous learning management system issues; create community belongingness; and support student collaboration; however, such uses also may allow a loss of privacy.

[
J Nurs Educ
. 2024;63(1):6–9.]
Entre crainte et diplomatie. Le paradoxe du détournement de la crue du Nil dans la diplomatie entre l’Égypte et l’Éthiopie (xive‑xve siècles)
Authors: Weber Benjamin 
Published: January 2024

À partir de la fin du xiie siècle, une légende circulant en Égypte attribue aux rois d’Éthiopie le pouvoir de bloquer la crue du Nil. Entre le début du xive et la fin du xve siècle, cette croyance est mentionnée dans de nombreuses sources arabes à propos des échanges diplomatiques entre l’Éthiopie et l’Égypte, laissant certains historiens penser qu’elle fut une menace régulièrement brandie par les rois chrétiens pour affirmer leur puissance face aux sultans musulmans. L’examen détaillé des sources éthiopiennes à notre disposition semble pourtant indiquer que cette histoire ne circulait pas encore en Éthiopie à cette période. Cet article tente de comprendre les ressorts de l’emploi de cette légende dans ses différents contextes et de résoudre le paradoxe d’une histoire inconnue en Éthiopie mais mentionnée dans les discours et lettres des rois éthiopiens.
« Este, dizem, que corre ao longo do Nilo ». Le Nil dans le récit de Francisco Álvares (1520-1526)
Authors: Alain Mathilde 
Published: January 2024

De son voyage en Éthiopie (1520-1526), Francisco Álvares rapporte quantité d’informations notamment géographiques sur l’Éthiopie, qu’il consigne dans un récit imprimé au Portugal en 1540 sous le titre Ho Preste Joam das indias. On y trouve des allusions au Nil, mais puisqu’Álvares n’a pas vu le fleuve, il s’en sert comme d’un référent géographique, un repère lui permettant de situer et de délimiter l’espace géographique éthiopien. Nombre d’informations à propos du Nil lui ont été rapportées par des Éthiopiens, à partir desquelles se dessine une perception de l’espace géographique organisé autour du réseau hydrographique éthiopien. Le Nil est également associé à un ensemble de connaissances géographiques témoignant autant de la culture d’Álvares que de la façon dont il a été influencé par ses informateurs. La comparaison du récit avec la version italienne de Ramusio, intégrée dans les Navigationi et Viaggi (Venise, 1550) atteste d’une réutilisation des informations géographiques fournies par Álvares, complétées dans le texte lui‑même et adaptées en cartes par Giacomo Gastaldi. La réception du texte d’Álvares souligne ainsi la fascination et l’intérêt occidental pour Le Nil au milieu du xvie siècle.
Commémorations de naissances et de baptêmes. Le cas des graffiti arabes du temple d’Isis à Philae (Assouan, fin du ive/xe siècle)
Authors: Lagaron-Khalifa Anna 
Published: January 2024

Les graffiti présentés dans cet article proviennent du temple d’Isis sur l’île de Philae (Assouan) et sont, pour l’heure, uniques en leur genre. Il s’agit d’un groupe de deux graffiti qui constituent en fait des inscriptions commémoratives de naissances et de baptêmes datées de la fin du ive/xe siècle. Ce sont des témoignages précieux de quelques chrétiens de Haute-Égypte qui, ayant baptisé leurs enfants, ont fait le choix de laisser une trace de cet acte en langue arabe à une période où on les considère comme à peine arabisés. C’est également le témoignage de naissances où les noms de musulmans et d’un chrétien apparaissent au sein d’une même inscription durant une époque connue comme une période d’entente mutuelle entre communautés. Ainsi, ces modestes graffiti semblent porteurs d’informations qui viennent à la fois bousculer et conforter les connaissances sur les chrétiens d’Égypte et il nous semble de fait important de les mettre en lumière dans cet article.
Sunt verba et voces praetereaque nihil ou la restitution d’une chronique almohade oubliée al‑Mann bi‑l‑Imāma
Authors: Ghouirgate Mehdi 
Published: January 2024

Les sources favorables aux Almohades restent rares. On ne peut, tout au plus, recenser que deux ou trois ouvrages, partiellement redécouverts en Europe sous la forme d’unicum. La chronique appelée al‑Mann bi‑l‑Imāma d’Ibn Ṣāḥib al‑Ṣalāt relève de ce cas de figure. L’aspect aussi original que déroutant du titre et de la structure du récit contribua à rebuter les spécialistes de l’histoire de l’Occident musulman retardant d’autant sa publication. La prépondérance des lettres de chancellerie et des vers que comportait al‑Mann bi‑l‑Imāma conduisit à déconsidérer cette source pourtant essentielle. De plus, la citation latine : « sunt verba et voces et praeteraque nihil » qu’associèrent Reinhart Dozy puis Ambrosio Huici Miranda à al‑Mann bi‑l‑Imāma afin de dénigrer cette chronique a probablement participé à ce qu’elle ne fasse pas l’objet d’une édition intégrale. C’est la volonté de doter le Maroc et le monde arabe d’une nouvelle source à même d’éclairer « son passé » qui amena un lettré marocain, Abdelhadi Tazi, à en réaliser une édition critique en 1964.
Ḥūš al‑Bāšā. The Royal Cemetery in Cairo
Authors: Kolkailah Mai Mohamed 
Published: January 2024

This article focuses on Ḥūš al‑Bāšā, the Royal Cemetery near the mausoleum of al‑Imām al‑Šāfʿī. First, the historiography of Ḥūš al‑Bāšā is examined in order to situate the mausoleum dynastically and geographically. Then, this study carefully reconstructs the complicated building chronology of Ḥūš al‑Bāšā by cross‑referencing contemporary sources with eyewitness accounts of nineteenth‑century travelers and drawings by Pascal Coste as well as Antonio Schranz Jr. to reassess when the mausoleum was built. In the course of critically rewriting the historical narrative of Ḥūš al‑Bāšā, this study maps the cemetery’s blend of appropriated decorative motifs to their original models of inspiration with the purpose of analyzing the eclectic tendencies of Ḥūš al‑Bāšā’s creative process and the definition of what constituted the Ottoman stylistic tradition in the nineteenth century. Finally, a comparative trajectory between the artistic milieus in the imperial state of Istanbul and the khedival province of Cairo is developed to question the vectors of influence driving the westernization of Ḥūš al‑Bāšā’s stylistic evolution. Ḥūš al‑Bāšā arguably represents a manifestation of power, a moment of decisive visual transformation, and a memory of a modernizing social order.
مساكن كبار رجال الدين في مصر القرن التاسع عشر. سراي الشيخ محمد العباسي المهدي بالقاهرة أنموذجا
Authors: عبد الفتاح عبد الوهاب 
Published: January 2024

Documents, especially architectural and construction records, are considered as one of the most important sources for the study of extant and disappeared buildings. They unquestionably reflect their history and original architecture without any falsification or ambiguity. The architectural and construction documents of the sarāy of Sheikh Muḥammad al-ʿAbbāsī al-Mahdī in Cairo are one of the best examples.This sarāy owes its architectural importance to the fact that it served as a model for the residences of Egyptian great clergy in the 19th Century and its historical importance to the association of its construction and architecture with a personality who played a crucial role in the religious and political affairs at that time. Despite the changes its architecture has undergone, whether through removal or addition, it has been possible to study it thanks to the documents gathered in the National Archives in Cairo.This study is in four parts. The first is a critical edition of the architectural and construction documents of this sarāy. The second is a documented reconstruction of the biography of its founder. The third is a study of its architecture, based on the architectural and construction documents. The fourth addresses the main factors that have affected its architecture.
Le Kitāb Ṭirāz al‑dahr fī asrār al‑ḫalq wa‑l‑amr de Ǧāmāsp dans la rédaction de Muḥammad ibn Abī Bakr al‑Fārisī (viie/xiiie siècle) (Milan, Ambrosienne C. 86)
Authors: Ducène Jean-Charles , Somer Florence 
Published: January 2024

Le Kitāb Ṭirāz al-dahr fī asrār al‑ḫalq wa‑l‑amr, rédigé à partir d’un modèle iranien par l’astronome yéménite Muḥammad ibn Abī Bakr al‑Fārisī (viie/xiiie siècle), donne à connaître des prédictions astrologiques attribuées à un sage persan préislamique, Ǧāmāsp. Ce texte témoigne cependant de la poursuite et de l’adaptation de ce genre à l’époque musulmane et en particulier au viie/xiiie siècle, période durant laquelle les sociétés proche-orientales sont politiquement bouleversées. En outre, ce traité démontre aussi la prégnance de l’astrologie historique selon une opérationnalité iranienne – les conjonctions planétaires – dans la pensée de l’époque et singulièrement au Yémen rasūlide, pour justifier les événements politiques et religieux passés ainsi que prévoir ceux à venir. Dans ce cas particulier, la prédiction apporte une légitimité astrologique à l’accession au pouvoir du sultan rasūlide al‑Muẓaffar Yūsuf (m. 694/1295), par ailleurs dédicataire du traité.
Rivière de l’or et Paradis terrestre. Le Nil dans les cartes et récits de voyage de la fin du Moyen Âge
Authors: Vagnon Emmanuelle 
Published: January 2024

Si la question des sources du Nil et de l’explication de ses crues remonte à l’Antiquité, les auteurs chrétiens ont souvent mentionné également son origine paradisiaque à l’Orient du monde. Mais c’est à la fin du Moyen Âge que deux autres thèmes commencent à être associés à la géographie mythique du Nil : d’une part les connexions possibles du fleuve égyptien avec un « fleuve de l’or » de l’Afrique occidentale, d’autre part la maîtrise du cours du fleuve en amont de l’Égypte par un potentiel prince chrétien, le fameux « Prêtre Jean ». Puis au xve siècle, on imagine un bras du Nil coulant cette fois de l’Orient à l’Occident, et identifié avec le Niger ou le Sénégal. Ainsi, le cours du Nil n’est pas seulement une question de géographie savante, mais comprend de bien réels enjeux politiques et économiques. À travers l’étude de textes, notamment de récits de pèlerinages, et de cartes des xive et xve siècles, nous étudierons comment ces thèmes sont diffusés à travers différents supports dans la culture occidentale médiévale.
Les sculptures romaines maritimes de Forum lulii
Authors: Lemoine Yvon 
Published: January 2024

À ce jour, la cité de Forum lulii a livré trois représentations sculptées en rapport avec la mer : une ronde-bosse du dieu Triton mêlant symbolisme augustéen et protection mythologique maritime ainsi que deux chapiteaux de pilastres sculptés de dauphins qui témoignent d’une mode stylistique. Plusieurs découvertes architecturales monumentales en bordure du bassin portuaire témoignent d’une décoration marmoréenne somptueuse très partiellement connue. Une partie de l’élévation de grands monuments publics à qui appartenaient ces blocs colossaux peut ponctuellement être restitué en y appliquant des calculs métrologiques. En revanche, la sculpture du port antique n’est aujourd’hui connue qu’à travers une unique sculpture du dieu Triton dérivée d’un modèle hellénistique. La présente étude livre des propositions de mise en scène de la statue dans le paysage portuaire encore trop méconnu.
CTLA-4 Checkpoint Inhibition Improves Sepsis Survival in Alcohol-Exposed Mice
Authors: Paterson Cameron W , Fay Katherine T , Chen Ching-Wen , Klingensmith Nathan J , Gutierrez Melissa B , Liang Zhe , Coopersmith Craig M , Ford Mandy L 
Published: January 2024

Abstract
Chronic alcohol use increases morbidity and mortality in the setting of sepsis. Both chronic alcohol use and sepsis are characterized by immune dysregulation, including overexpression of T cell coinhibitory molecules. We sought to characterize the role of CTLA-4 during sepsis in the setting of chronic alcohol exposure using a murine model of chronic alcohol ingestion followed by cecal ligation and puncture. Results indicated that CTLA-4 expression is increased on CD4+ T cells isolated from alcohol-drinking septic mice as compared with either alcohol-drinking sham controls or water-drinking septic mice. Moreover, checkpoint inhibition of CTLA-4 improved sepsis survival in alcohol-drinking septic mice, but not water-drinking septic mice. Interrogation of the T cell compartments in these animals following pharmacologic CTLA-4 blockade, as well as following conditional Ctla4 deletion in CD4+ T cells, revealed that CTLA-4 deficiency promoted the activation and proliferation of effector regulatory T cells and the generation of conventional effector memory CD4+ T cells. These data highlight an important role for CTLA-4 in mediating mortality during sepsis in the setting of chronic alcohol exposure and may inform future approaches to develop targeted therapies for this patient population.
Blood component therapy in patients having massive obstetric hemorrhage in a tertiary care center in Puducherry
Authors: Anuragaa S. , Chaturvedula Latha , Basavarajegowda Abhishekh 
Published: January 2024

Abstract

INTRODUCTION:
A proper transfusion protocol must be followed for every patient with massive obstetric hemorrhage (MOH), as each patient may need a different pattern of transfusion support. In this background, it is prudent to understand the current prevalent practices and devise preparatory strategies for managing blood requirements during such scenarios. This study helps us know the pattern and type of blood components given to patients with MOHs.

METHODOLOGY:
This prospective cross-sectional study was conducted on patients with a MOH admitted to a single center at a tertiary care teaching hospital in Puducherry between January 2020 and October 2021. During the hospital stay, patient parameters such as diagnosis, obstetric history, blood loss, transfusion of blood products, transfusion reaction, blood group, length of hospital stay, laboratory parameters, and patient vitals and comorbidities were recorded in a predesigned pro forma and tabulated into Excel sheet and analyzed using SPSS software version 19.0.

RESULTS:
Fifty-four patients with MOH were included in our study. The median blood loss was 2.15 L, with a range of 2 L. The mean difference between the baseline and posthemorrhage hemoglobin is 1.7 g/dl. No correlation was observed between the number of packed red blood cell (PRBC) transfused and baseline hemoglobin or between random donor platelets (RDP) transfusion and baseline platelet count. The median number of hospital stays was 10 days, ranging from 7 to 14.5 days. Eleven (20.38%) patients had a hysterectomy done to control bleeding. The remaining 43 patients were managed successfully by other measures such as medical management, compressive surgical suturing, and arterial ligation. Forty-eight (88.9%) patients survived, and 6 (11.1%) patients expired.

CONCLUSION:
The percentage of RDP and cryoprecipitate transfused to the patients was less than PRBC and fresh frozen plasma (FFP). The FFP-to-PRBC ratio was 2. Regular transfusion audits must be conducted to assess the flaws and improve current strategies.