bluuebunny/crossref_metadata_2025_split huggingface dataset:
Edukasi Penyimpanan dan Pembuangan Obat Rusak/ Expire date dalam Keluarga
Authors: Rasdianah Nur , Uno Wiwit Zuriati 
Published: December 2023

Pengetahuan masyarakat mengenai dunia kesehatan, terutama obat masih sangat terbatas, padahal obat merupakan bahan yang mudah kita temukan di sekitar kita. Obat harus selalu digunakan secara benar agar memberikan manfaat klinik yang optimal. Pada kegiatan ini dilakukanEdukasi dalam bentuk penyuluhan tentang Penyimpanan dan Pembuangan Obat Rusak/ Expire date dalam Keluarga di Desa Buata. Penyimpanan dan pembuangan obat merupakan suatu masalah penting di Indonesia. Dalam skala rumah tangga, penyimpanan obat yang kurang baik dapat menyebabkan permasalahan serius, seperti keracunan obat secara tidak sengaja. Selain itu, pembuangan atau pemusnahan obat yang kurang benar selanjutnya memunculkan potensi terjadinya daur ulang illegal kemasan atau produk obat kadaluarsa. Metode yang dipakai dalam mencapai tujuan tersebut adalah kegiatan sosialisasi atau edukasi yaitu dengan menjelaskan materi kepada masyarakat dan melakukan pembagian leafleat tentang cara penyimpanan obat dan cara membuang obat dengan baik dan benar. Pada kegiatan Edukasi tentang cara penyimpanan obat yang baik dan benar akan membahas materi tentang obat, jenis jenis obat, Kemudian penjelasan sediaan obat dan cara penggunaannya, perlu perhatian khusus agar tidak salah dalam menggunakannya serta tata cara penyimpanan dan pembuangan obat yang baik dan benar berdasarkan bentuk sediaan obat.
Pelatihan Kader Posyandu Sebagai Upaya Pencegahan Stunting pada Balita di Desa Lonuo Kecamatan Tilongkabila
Authors: Amalia Lia , Makkulawu Andi 
Published: December 2023

Masalah kurang gizi dan stunting merupakan dua masalah yang saling berhubungan. Pencegahan stunting menjadi tanggung jawab bersama. Kader posyandu sebagai perwakilan masyarakat memiliki peran yang besar demi terlaksananya intervensi yang efektif untuk menurunkan angka stunting balita. Peningkatan kapasitas kader posyandu sangatlah penting untuk memberikan pengetahuan tentang tugas dan peran kader posyandu, sehingga diharapkan kedepan pelayanan posyandu akan lebih baik. Kader posyandu sebagai perpanjangan tangan Puskesmas dalam memantau tumbuh kembang anak harus berperan lebih aktif untuk menciptakan generasi muda yang lebih produktif. Kegiatan pengabdian kepada masyarakat ini dilaksanakan dengan memberikan pelatihan kepada kader Posyandu. Tujuan dari kegiatan adalah untuk meningkatkan pengetahuan dan keterampilan kader Posyandu sebagai upaya pencegahan stunting pada balita.
Pembuatan Teh dan Sirup Daun Bandotan Sebagai Terapi Komplementer Hiperkolesterolmia Masyarakat Lampo Kabupaten Donggala
Authors: Magfirah Magfirah , Utami Indah Kurnia 
Published: December 2023

Hiperkolesterolmia merupakan kondisi di mana kadar kolesterol total dalam darah meningkat hingga melebihi batas normal (120-200 mg/dl) yang di sebabkan karna gangguan metabolism lemak. Kadar kolesterol yang tinggi juga dapat menyebabkan rasa sakit di dada bagian depan atau pada lengan ketika seseorang tersebut stres atau melakukan kegiatan fisik. Salah satu jenis terapi komplementer yang dapat dimanfaatkan untuk mengatasi hiperkolesterolemia yang terjadi adalah dengan pemberian teh dan sirup daun bandotan karena mengandung senyawa farmakologis seperti alkaloid, saponin, tannin dan flavonoid. Teh dan Sirup Bandotan kadalah produk siap saji yang banyak diminat dari berbagai kalangan mulai dari anak-anak,dewasa dan orang tua. Teh dan Sirup Bandotan merupakan sejenis minuman ringan berupa larutan dengan cita rasa beraneka ragam. Bahan utama yang digunakan pada pembuatan Teh dan Sirup pada pengabdian ini yaitu herba bandotan, daun stevia dan air. Kegiatan Pengabdian bertujuan untuk meningkatkan pengetahuan dan ketrampilan masyarakat desa Lampo, Kecamatan Banawa Tengah , Kabupaten Donggala dalam pemanfaatan tanaman bandotan berkhasiat obat menjadi teh dan sirup herbal yang siap dikonsumsi dan dipasarkan. Metode yang digunakan berupa sosialisasi dan pelatihan pembuatan teh dan sirup tanaman herbal berkhasiat obat secara berkesinambungan. Efektivitas kegiatan dapat diuji dengan kuisiner kepuasan mitra terhadap kegiatan yang dilaksanakan. Hasil pengamatan kegiatan menunjukkan bahwa mitra merasa puas. Luaran kegiatan berupa peningkatan pengetahuan tentang tanaman berkhasiat obat, produk herbal (teh, jamu, sirup) hasil buatan masyarakat (mandiri) yang siap dipasarkan, dan publikasi jurnal nasional.
TOI-5344 b: A Saturn-like Planet Orbiting a Super-solar Metallicity M0 Dwarf
Authors: Han Te , Robertson Paul , Kanodia Shubham , Cañas Caleb , Lin Andrea S. J. , Stefánsson Gumundur , Libby-Roberts Jessica E. , Larsen Alexander , Kobulnicky Henry A. , Mahadevan Suvrath , Bender Chad F. , Cochran William D. , Endl Michael , Everett Mark E. , Gupta Arvind F. , Halverson Samuel , Hearty Fred , Monson Andrew , Ninan Joe P. , Roy Arpita , Schwab Christian , Terrien Ryan C. 
Published: December 2023

Abstract
We confirm the planetary nature of TOI-5344 b as a transiting giant exoplanet around an M0-dwarf star. TOI-5344 b was discovered with the Transiting Exoplanet Survey Satellite photometry and confirmed with ground-based photometry (the Red Buttes Observatory 0.6 m telescope), radial velocity (the Habitable-zone Planet Finder), and speckle imaging (the NN-Explore Exoplanet Stellar Speckle Imager). TOI-5344 b is a Saturn-like giant planet (ρ = 0.80

−
0.15

+
0.17

g cm−3) with a planetary radius of 9.7 ± 0.5 R
⊕ (0.87 ± 0.04 R
Jup) and a planetary mass of

135

−
18

+
17

M

⊕

(0.42

−
0.06

+
0.05

M

Jup

). It has an orbital period of

3.792622

−
0.000010

+
0.000010

days and an orbital eccentricity of

0.06

−
0.04

+
0.07

. We measure a high metallicity for TOI-5344 of [Fe/H] = 0.48 ± 0.12, where the high metallicity is consistent with expectations from formation through core accretion. We compare the metallicity of the M-dwarf hosts of giant exoplanets to that of M-dwarf hosts of nongiants (≲8 R
⊕). While the two populations appear to show different metallicity distributions, quantitative tests are prohibited by various sample caveats.
Chemical Homogeneity of Wide Binary Systems: An Approach from Near-Infrared Spectroscopy
Authors: Lim Dongwook , Koch-Hansen Andreas J. , Hong Seungsoo , Chun Sang-Hyun , Lee Young-Wook 
Published: December 2023

Abstract
Wide binaries, with separations between the two stars from a few au to more than several thousand au, are valuable objects for various research topics in Galactic astronomy. As the number of newly reported wide binaries continues to increase, studying the chemical abundances of their component stars becomes more important. We conducted high-resolution near-infrared (NIR) spectroscopy for six pairs of wide binary candidates using the Immersion Grating Infrared Spectrometer at the Gemini-South telescope. One pair was excluded from the sample due to a significant difference in radial velocity between its component stars, while the remaining five pairs exhibited homogeneous properties in 3D motion and chemical composition among the pair stars. The differences in [Fe/H] ranged from 0.00 to 0.07 dex for these wide binary pairs. The abundance differences between components are comparable to the previous results from optical spectroscopy for other samples. In addition, when combining our data with literature data, it appears that the variation of abundance differences increases in wide binaries with larger separations. However, SVO 2324 and SVO 3206 showed minimal differences in most elements despite their large separation, supporting the concept of multiple formation mechanisms depending on each wide binary. This study is the first approach to the chemical properties of wide binaries based on NIR spectroscopy. Our results further highlight that NIR spectroscopy is an effective tool for stellar chemical studies based on equivalent measurements of chemical abundances from the two stars in each wide binary system.
Pharmacological methods for weight reduction and their connection with the human gut microbiota
Authors: Denchev Venelin Dimitrov , Handjieva-Darlenska Teodora Svetoslavova 
Published: December 2023

In the beginning of the twenty-first century, obesity has become a concerning world-wide issue due to its high prevalence in modern society. It is a metabolic disorder, caused by excessive accumulation of adipose tissue in the human organism – the main reason for which is increased caloric intake and decreased caloric expenditure in combination with dysregulation of hunger. It is a chronic systematic disease that leads to the development of a large number of health complications, the most common of which are: diabetes mellitus type 2, arterial hypertension, atherosclerosis, sleep apnea, different types of cancer and more.
During the last decade, significant advancements have been made in regard to treatment of many endocrine and metabolic conditions, using pharmacological means, and some of these novel medications have proven to be an effective therapy for obesity. There is emerging evidence that such drugs can exhibit an effect over the human gut microbiota – the complex system of commensal bacteria located in the gastrointestinal tract, which could affect appetite, mucosal integrity, nutrient absorption, and that interaction can be the key to understanding the pathogenesis of obesity and its treatment.
Solidarité ou sécurité ?
Authors: Simonneau Damien , Castelli Gattinara Pietro 
Published: December 2023

L’article interroge comment des savoirs experts produits « par le bas » participent au processus de politisation et de dépolitisation de l’action publique en matière d’immigration en France depuis 2017. Il compare l’expertise de groupes anti-migrants, qui sous le registre de la « crise migratoire » prônent un contrôle frontalier renforcé, à celle des mouvements solidaires qui dénoncent des pratiques étatiques au nom de l’accueil. La comparaison de ces mobilisations antagonistes fait émerger des similarités importantes dans l’usage des savoirs experts dans une politique migratoire construite sous l’angle du contrôle. Dans les deux cas, la constitution d’une expertise ne se traduit pas nécessairement par de la dépolitisation et apparaît comme une ressource politique ambivalente. Elle sert avant tout à ces mouvements d’outil de légitimation pour être audible dans l’action publique. Les anti-migrants se constituent en experts par mimétisme du langage et des codes techniques de leurs adversaires dans le but d’atténuer le caractère idéologique de leurs positionnements xénophobes qui autrement manqueraient de légitimité dans l’espace public. En revanche, les acteurs solidaires mettent en avant l’expertise acquise par l’observation et la participation à la gestion étatique de l’immigration afin de repolitiser l’action publique et revendiquer davantage de participation citoyenne.
« Maintenir les liens » en temps de captivité. Transmission et circulation de l’information entre la France et l’Allemagne durant la Seconde Guerre mondiale
Authors: Siassia Amarillys 
Published: December 2023

Plus d’un million et demi de prisonniers de guerre français ont été déplacés vers des camps en Allemagne après la défaite de juin 1940. Cette captivité bouleverse la société française et redéfinit les relations entre la France et l’Allemagne. Dans ce contexte, garantir la transmission et la circulation des lettres et des colis entre ces deux espaces apparaît comme un enjeu politique, économique et social majeur pour les autorités françaises et allemandes.
Cytomegalovirus Infection Facilitates the Costimulation of CD57+CD28− CD8 T Cells in HIV Infection and Atherosclerosis via the CD2–LFA-3 Axis
Authors: Winchester Nicole E , Panigrahi Soumya , Haria Anokhi , Chakraborty Archeesha , Su Xi , Chen Bonnie , Morris Stephen R , Clagett Brian M , Juchnowski Steven M , Yadavalli Raghavendra , Villinger Francois , Paiardini Mirko , Harth Karem , Kashyap Vikram S , Calabrese Leonard H , Margolis Leonid , Sieg Scott F , Shive Carey L , Gianella Sara , Funderburg Nicholas T , Zidar David A , Lederman Michael M , Freeman Michael L 
Published: December 2023

Abstract
CD8 T cells are emerging as important mediators in atherosclerosis and cardiovascular disease (CVD). Immune activation may play a particular role in people with HIV (PWH) who are at an increased risk of CVD, even after controlling for known CVD risk factors. Latent CMV infection is associated with increased CVD risk for both PWH and people without HIV, and human CMV-specific CD4 and CD8 T cells are enriched for an immunosenescent phenotype. We previously showed that CMV coinfection in PWH promotes vascular homing and activation of inflammatory CD4 T cells through the CD2–LFA-3 axis. However, the role of CD2/LFA3 costimulation of CD8 T cells in PWH with CMV has yet to be described. In the present study, we demonstrate that CD2 expression on CX3CR1+CD57+CD28− inflammescent CD8 T cells is increased on cells from CMV-seropositive PWH. In vitro CD2/LFA-3 costimulation enhances TCR-mediated activation of these inflammatory CD8 memory T cells. Finally, we show that LFA-3 is highly expressed in aortas of SIV-infected rhesus macaques and in atherosclerotic plaques of people without HIV. Our findings are consistent with a model in which CMV infection enhances CD2 expression on highly proinflammatory CD8 T cells that can then be stimulated by LFA-3 expressed in the vasculature, even in the absence of CD28 costimulation. This model, in which CMV infection exacerbates toxic cytokine and granzyme production by CD8 T cells within the vasculature, highlights a potential therapeutic target in atherosclerosis development and progression, especially for PWH.
Appropriateness of Hospital Admission and Length of Stay in the Pediatric Department of a Tertiary Care Hospital in West Bengal
Authors: Samanta Sampriti , Bandyopadhyay Alapan , Mukherjee Abhijit , Bhattacherjee Sharmistha 
Published: December 2023

Abstract

Background:
Appropriateness of admissions and inpatient length of stay (LOS) are important factors controlling health-care expenditure. The current study was conducted to assess the proportion of appropriate admissions among 29-day to 12-year--old aged patients admitted to pediatric wards of a tertiary health-care center in one month and evaluate inappropriate LOS among them.

Materials and Methods:
An observational longitudinal study was carried out for two months among patients admitted to the pediatric inpatient department using Pediatric Appropriateness Evaluation Protocol (PAEP)-II tool. All patients admitted to the institution during the study period were included in the study.

Results:
Among 495 children, 438 (88.5%) were appropriately admitted. Inappropriate admission was mostly found in children aged 1 to 5 years (29, 16.6%), those who lived >5 km from the hospital (45, 15.2%), and those who presented with other systemic illnesses (13, 31.7%). Among the appropriately admitted children, 333 (76%) met the criteria of appropriate LOS during their hospital stays. Multivariable logistic regression showed that the age of the children (AOR = 0.99; 95% CI = 0.98, 0.99), age-appropriate feeding (AOR = 2.12;95% CI = 1.30,3.47), and hematological disorder (AOR = 0.16; 95% CI = 0.05, 0.52) were found to be associated with the children being kept at the hospital inappropriately.

Conclusions:
The current study observed a high proportion of appropriate admission in children. However, a higher proportion of inappropriate LOS among them was seen. The younger age group, age-appropriate feeding, and type of illness were found as the primary predictors for inappropriate LOS.
Review of the Screening Guidelines for Gestational Diabetes Mellitus: How to Choose Wisely
Authors: Bakshi Ravleen Kaur , Kumar Akshay , Gupta Vandana , Radhika A.G. , Misra Puneet , Bhardwaj Pankaj 
Published: December 2023

Abstract
Currently, there is no international unanimity regarding the timings, the optimal cut-off points, and standardized methods of screening or diagnosis of gestational diabetes mellitus (GDM). The screening guidelines and recommendations for GDM evolved over time; concise information has been presented here in the review. We searched electronic databases for various guidelines for screening of GDM in PubMed, Medical Literature Analysis and Retrieval System Online (MEDLINE), Embase, Cochrane, Google Scholar, Scopus, Guidelines International Network (GIN library), National Guidelines Clearinghouse (NGC); Web sites of relevant organizations; and trial registries. The mesh headings derived after reviewing the articles and were used to further search the articles are: (“Screening Guidelines GDM” or “Screening Criteria for GDM”) and (“Glucose Intolerance in Pregnancy” or “Gestational Diabetes Mellitus”). The articles published from 1960 till December 2022 were included. Key outcomes included the prevalence of GDM is 14.6% according to the International Association of Diabetes and Pregnancy Study Groups (IADPSG) criteria and 13.4% according to Diabetes in Pregnancy Study Group India (DIPSI) criteria, making the DIPSI criterion a cost-effective method for low-resource settings. The IADPSG) criterion diagnoses and treats GDM earlier, thus reducing the complications associated with GDM in the mother and newborn. The IADPSG criteria at a cut-off of ≥140 mg/dL have a sensitivity of 81% and specificity of 93%, whereas the World Health Organization (2013) criteria at the same cut-off has a lower sensitivity of 59% and specificity of 81%. The risk factors of having GDM are family history, history during past pregnancy, medical history, multiple current pregnancies, and raised hemoglobin A1c. The screening guidelines have been developed by different organizations and institutions over the years. The guidelines with the threshold values for screening and their standardization for detecting GDM in Indian mothers are yet to be established.
Debunking Claims and Prioritizing Public Health: India’s Bold Stand against Tobacco Imagery on OTT Platforms
Authors: Goel Sonu , Nawani Srishti 
Published: December 2023

Abstract
India has taken a ground-breaking step in public health by mandating anti-tobacco warnings and disclaimers on over-the-top (OTT) platforms. Concerns over the prevalence of tobacco imagery in media, including OTT platforms, prompted this decision due to its role in normalizing and glamorizing smoking, particularly among the youth. The Indian government aims to comprehensively address this issue and protect public health. This article reviews recent news articles on the developments in the 2023 amendments to Cigarette and other tobacco products act COTPA 2004 and relevant studies on the ill effects of tobacco imagery to form the viewpoint. To effectively implement the new order, clear guidelines, and standards need to be established. Additionally, comprehensive awareness and education campaigns should be launched, while strict monitoring and enforcement mechanisms must be implemented. Supporting research initiatives should evaluate the impact of the warnings, and multiple stakeholders should be involved in the decision-making process. India’s commitment to protecting public health and curbing tobacco advertisements on OTT platforms necessitates clear guidelines, awareness campaigns, monitoring and enforcement mechanisms, research initiatives, and stakeholder engagement. This government order aligns with international public health frameworks and can serve as a precedent for other countries. By implementing these measures, we can counter the normalization and glamorization of tobacco use and create a healthier future.
Anemia in Indian Men: An Emerging Public Health Challenge
Authors: Saxena Vartika , Singh Meghna 
Published: December 2023

Abstract
Approximately one-quarter of the world’s population is suffering from anemia, out of which 12.7% of men suffer from anemia around the globe. In India, anemia is a moderate public health problem (ranging from 20 to 39.9%). Prevalence of anemia is 25% in men and 31% in adolescent boys, in India. In recent years, there has been an alarming rise in anemia prevalence among adolescent boys (15–19 years) in 23 states, and among men (15–49 years) in 17 states. Anemia in the states of Jammu and Kashmir and Ladakh is a severe public health problem. Despite being a vital issue, indicators for anemia in men are not given due importance in national health statistics reports. This article highlights the issue to prioritize men’s health in the context of anemia at state and national levels.
Challenges Faced and Coping Strategies Adopted by Injecting Drug Users during COVID-19 Lockdown—A Qualitative Study
Authors: Vashisht Shruti , Jha Shreya , Kant Shashi , Thakur Nishakar , Rai Sanjay 
Published: December 2023

Abstract

Background:
The lockdown due to COVID-19 pandemic has adversely affected the lives of vulnerable population, including the injecting drug users (IDUs). The objective of the study was to document the coping mechanism adopted by IDUs and suggest measures to mitigate the adverse effects, if similar situation were to arise in future.

Materials and Methods:
A qualitative study was conducted at the Targeted Intervention Non-Government Organizations catering to IDUs in Delhi and Ghaziabad district of Uttar Pradesh. Four focus group discussions among 41 IDUs and 7 key informant interviews of the NGO staff were conducted in the study. The Hindi recordings were coded and the data analysis was performed manually using grounded theory approach.

Results:
We found that the lockdown affected the lives of most of the IDUs and they found it difficult to access the harm reduction services. To cope with this, many IDUs started following alternate methods to support the drug habits. There was an increase in reuse of needles and syringes.

Conclusion:
The lockdown during COVID-19 and the resulting challenges negatively impacted the physical and mental health of the IDUs. We recommend that in any similar future scenario, travel pass may be issued to the IDUs and the TI-NGO personnel.
Epidemiological and Time Series Analysis of Tuberculosis with Prediction during COVID-19 Pandemic using ARIMA Model: A Study from Churu District of Rajasthan
Authors: Singh Rajesh K. , Panwar Ravi , Choudhary Kavita , Matta Shanker , Pant Ashish 
Published: December 2023

Abstract
As Tuberculosis (TB) is a major public health problem in India and to achieve the goal of TB elimination, it is important to assess the trend of TB cases and the impact of lockdowns and other restrictions imposed for control of COVID-19 in India on the National TB Elimination Programme. Hence, the present study aims to study the temporal trend of TB cases and assess the impact of lockdown on TB detection. A retrospective record-based study was conducted in a tertiary care institute of India. A time series analysis of TB cases from April 2018 to May 2020 was carried out. An Auto-Regressive Integrated Moving Averages (ARIMA) model was used to forecast TB cases during the lockdown period and the result was compared with actual cases detected. The statistical analysis was accomplished with R software. The time series analysis showed that the projected TB cases in April and May 2020 were 67 and 86, respectively, while the observed cases in these months were 35 and 76. The trend of TB cases during the study period showed no steady increase or decrease and the detection of TB has declined during the COVID-19 lockdown period. The TB cases peaked from April to June and males constitute the majority of TB cases.