bluuebunny/crossref_metadata_2025_split huggingface dataset:
“Orlando soy, Quijote, que, perdido / por Angélica, vi remotos mares”: Los viajes del Orlando furioso de Ariosto entre Italia y España”
Authors: Muñoz Sánchez Juan Ramón 
Published: November 2023

Resumen
El siguiente estudio pretende ofrecer un análisis del complejo proceso de composición del Orlando furioso de Ludovico Ariosto, de su extraordinaria difusión en Italia y de su decisiva contribución en la conformación del modelo del género editorial del libro de entretenimiento en Europa. Así como de su recepción en los reinos de la Monarquía Hispánica durante los siglos XVI y XVII, con especial atención a las traducciones realizadas por Jerónimo de Urrea, Hernando Alcocer, Diego Vázquez de Contreras y Gonzalo de Oliva, y de señalar algunas de las tareas pendientes más acuciantes a tal respecto.
“El poema dulcissimo del Tasso”. La Gerusalemme liberata en la España de finales del Quinientos
Authors: Vilà Lara 
Published: November 2023

Resumen
El artículo ofrece un panorama de las traducciones y adaptaciones de la Gerusalemme liberata en España y plantea su estudio desde la perspectiva del problema de la poesía heroica en el Quinientos y principios del Seiscientos. A partir del análisis de las circunstancias de escritura y difusión del poema, el estudio se detiene en las versiones de Juan Sedeño y Bartolomé Cairasco de Figueroa y atiende finalmente a las adaptaciones más tempranas que conoció el siglo y a algunas particularidades de su imitación en nuestras letras.
Intertextual Inquiry and Interpretive Creation: Pope.L’s Experimental Staging of William Wells Brown’s The Escape
Authors: Saal Ilka 
Published: November 2023

Abstract
This contribution discusses Pope.L’s 2018 provocative restaging of William Wells Brown’s anti-slavery play The Escape: Or, A Leap of Freedom (1858) at the Art Institute of Chicago. Drawing on Linda Hutcheon’s theory of adaptation, it argues against a source-oriented assessment of the production, which would prioritize the original over its interpretation and delimit aesthetic evaluation to questions of fidelity. It proposes to consider Pope.L: The Escape as an interpretive creation in its own right. Engaging in a complex intertextual and intercultural dialogue with its antetext, Pope.L’s staging brings into focus particular aspects of the contemporary moment. While Brown’s play presents race as first and foremost a performative category and stresses the possibility of autopoiesis qua performance, Pope.L reduces slavery to an ontological condition. Its title and manifold multimedia performances notwithstanding, there is no escape from enslavement in Pope.L: The Escape. Performance remains contained in and prescribed by an ongoing condition of physical and psychic enslavement. With this radical adaptation, Pope.L responds to what Paul Gilroy identifies as the “ontological turn” in recent Black thought. In light of the ongoing structural and quotidian violence against People of Color, this approach insists on the central significance of the bodily experience of racializing attributions for understanding social relations as well as Black collectivity. It also provocatively asks whether the performative does indeed suffice to unsettle the structural coordinates of anti-Blackness that continue to impact and overdetermine contemporary lives.
Creative Interpretation and the Politics of Failure
Authors: Lippert Leopold 
Published: November 2023

AbstractIn this article, I ask what happens to theatrical performance when it fails. By describing a performance as “failed,” I do not necessarily imply its normative dismissal – as a “flawed” enactment or an artistic vision not properly executed. Instead, I use failure as a conceptual starting point for the articulation of alternative meaning-making practices. In this sense, failure is a form of creative interpretation that capitalizes on performance’s constitutive contingency, its structural unreliability that for many is part of its appeal, the very “magic” only a gathering of live bodies can create. Specifically, the article looks at two recent US American plays and one musical in order to discuss the theatrical politics of failure: Moisés Kaufman and Tectonic Theater Project’sThe Laramie Project(2000), Ayad Akhtar’sThe Who and the What(2014), and Dave Malloy’sNatasha, Pierre & the Great Comet of 1812(2012). By discussing the ways in which these pieces and their performances creatively address failure, I point to three formal and cultural dimensions in which failure can be mobilized theatrically: first, failure problematizes the easy formal subsumption of performance under production, pointing to the ways in which a specific performance may not adequately actualize the conceptual work of the production, be it because audiences intervene in ways not intended by the production or because performers deviate from the production’s script in one way or another. Second, failure can be mobilized to reveal tacit cultural conventions or standards of success that entrench particular (classist, racist, sexist, ableist, etc.) normative behaviors. And third, failure can enable more creative approaches to the relationship between the labor of theater practitioners and its exchange value for spectators, who paid – at least – the price of a theater ticket and typically expect some form of artistic professionalism as remuneration.
Spiritual Wonderings: A Study of Phantasmagoria in Early Chinese Cinema
Authors: Wan Chuanfa , Wu Yanqing 
Published: November 2023

Abstract
Phantasmagoria (幻景 huanjing) is a term commonly seen in historical materials on early Chinese cinema. In this thesis, “Phantasmagoria” is taken as the localization of Western cinema tricks in early China. According to sources, “phantasmagoria” is valuable and rich in content, although it has no clear definition. This thesis seeks to define “phantasmagoria” and through a comparison of Chinese and Western cinema investigate which Western cinema tricks were appropriated and eventually labelled phantasmagoria. This article takes phantasmagoria to be a Chinese term, the meaning and application of which carry the traditional cultural ideas behind the localization of cinema tricks.
Patterns of differential expression by association in omic data using a new measure based on ensemble learning
Authors: Arevalillo Jorge M. , Martin-Arevalillo Raquel 
Published: November 2023

Abstract
The ongoing development of high-throughput technologies is allowing the simultaneous monitoring of the expression levels for hundreds or thousands of biological inputs with the proliferation of what has been coined as omic data sources. One relevant issue when analyzing such data sources is concerned with the detection of differential expression across two experimental conditions, clinical status or two classes of a biological outcome. While a great deal of univariate data analysis approaches have been developed to address the issue, strategies for assessing interaction patterns of differential expression are scarce in the literature and have been limited to ad hoc solutions. This paper contributes to the problem by exploiting the facilities of an ensemble learning algorithm like random forests to propose a measure that assesses the differential expression explained by the interaction of the omic variables so subtle biological patterns may be uncovered as a result. The out of bag error rate, which is an estimate of the predictive accuracy of a random forests classifier, is used as a by-product to propose a new measure that assesses interaction patterns of differential expression. Its performance is studied in synthetic scenarios and it is also applied to real studies on SARS-CoV-2 and colon cancer data where it uncovers associations that remain undetected by other methods. Our proposal is aimed at providing a novel approach that may help the experts in biomedical and life sciences to unravel insightful interaction patterns that may decipher the molecular mechanisms underlying biological and clinical outcomes.
Centriole elimination during Caenorhabditis elegans oogenesis initiates with loss of the central tube protein SAS‐1
Authors: Pierron Marie , Woglar Alexander , Busso Coralie , Jha Keshav , Mikeladze‐Dvali Tamara , Croisier Marie , Gönczy Pierre 
Published: November 2023

AbstractIn most metazoans, centrioles are lost during oogenesis, ensuring that the zygote is endowed with the correct number of two centrioles, which are paternally contributed. How centriole architecture is dismantled during oogenesis is not understood. Here, we analyze with unprecedent detail the ultrastructural and molecular changes during oogenesis centriole elimination in Caenorhabditis elegans. Centriole elimination begins with loss of the so‐called central tube and organelle widening, followed by microtubule disassembly. The resulting cluster of centriolar proteins then disappears gradually, usually moving in a microtubule‐ and dynein‐dependent manner to the plasma membrane. Our analysis indicates that neither Polo‐like kinases nor the PCM, which modulate oogenesis centriole elimination in Drosophila, do so in C. elegans. Furthermore, we demonstrate that the central tube protein SAS‐1 normally departs initially from the organelle, which loses integrity earlier in sas‐1 mutants. Overall, our work provides novel mechanistic insights regarding the fundamental process of oogenesis centriole elimination.
The 5:2 diet does not increase adult hippocampal neurogenesis or enhance spatial memory in mice
Authors: Roberts Luke D , Hornsby Amanda KE , Thomas Alanna , Sassi Martina , Kinzett Aimee , Hsiao Nathan , David Bethan R , Good Mark , Wells Timothy , Davies Jeffrey S 
Published: November 2023

AbstractNew neurones are generated throughout life in the mammalian brain in a process known as adult hippocampal neurogenesis (AHN). Since this phenomenon grants a high degree of neuroplasticity influencing learning and memory, identifying factors that regulate AHN may be important for ameliorating age‐related cognitive decline. Calorie restriction (CR) has been shown to enhance AHN and improve memory, mediated by the stomach hormone, ghrelin. Intermittent fasting (IF), a dietary strategy offering more flexibility than conventional CR, has also been shown to promote aspects of AHN. The 5:2 diet is a popular form of IF; however, its effects on AHN are not well characterised. To address this, we quantified AHN in adolescent and adult wild‐type and ghrelin‐receptor‐deficient mice following 6 weeks on a 5:2 diet. We report an age‐related decline in neurogenic processes. However, the 5:2 diet does not increase AHN nor enhance memory performance, suggesting that this specific form of IF is ineffective in promoting brain plasticity to support learning.
Microautophagy regulated by STK38 and GABARAPs is essential to repair lysosomes and prevent aging
Authors: Ogura Monami , Kaminishi Tatsuya , Shima Takayuki , Torigata Miku , Bekku Nao , Tabata Keisuke , Minami Satoshi , Nishino Kohei , Nezu Akiko , Hamasaki Maho , Kosako Hidetaka , Yoshimori Tamotsu , Nakamura Shuhei 
Published: November 2023

AbstractLysosomes are degradative organelles and signaling hubs that maintain cell and tissue homeostasis, and lysosomal dysfunction is implicated in aging and reduced longevity. Lysosomes are frequently damaged, but their repair mechanisms remain unclear. Here, we demonstrate that damaged lysosomal membranes are repaired by microautophagy (a process termed “microlysophagy”) and identify key regulators of the first and last steps. We reveal the AGC kinase STK38 as a novel microlysophagy regulator. Through phosphorylation of the scaffold protein DOK1, STK38 is specifically required for the lysosomal recruitment of the AAA+ ATPase VPS4, which terminates microlysophagy by promoting the disassembly of ESCRT components. By contrast, microlysophagy initiation involves non‐canonical lipidation of ATG8s, especially the GABARAP subfamily, which is required for ESCRT assembly through interaction with ALIX. Depletion of STK38 and GABARAPs accelerates DNA damage‐induced cellular senescence in human cells and curtails lifespan in C. elegans, respectively. Thus, microlysophagy is regulated by STK38 and GABARAPs and could be essential for maintaining lysosomal integrity and preventing aging.
The sonographer’s and pathologist’s perspective of echogenic microfoci in papillary thyroid carcinoma
Authors: Bahçecioğlu Adile Begüm , Gürsoy Alptekin , Dizbay Sak Serpil , Ilgan Seyfettin , Bilezikçi Banu , Erdoğan Murat Faik 
Published: November 2023

Objective
Punctate echogenic foci (PEF)/microcalcifications are thought to represent psammoma bodies (PB) in histopathology. However, there are few and contradictory data on this. Different types of sonographic echogenic microfoci (EMF) are seen in papillary thyroid carcinoma (PTC), and their histopathological equivalents are not clearly known. There is also conflicting data on the interobserver agreement between the sonographers on EMF.

Methods
We prospectively collected US video records of PTC nodules with and without EMF in two large thyroid centers. All video recordings were independently interpreted by three blinded, experienced sonographers. EMF were classified as true microcalcifications (punctate echogenic foci (PEF) ≤1 mm long), linear microechogenities (>1 mm long, posterior acoustic enhancement of the back wall of a microcystic area), comet-tail artifacts/reverberations or linear microechogenities with comet-tail artifacts/reverberations, non-shadowing coarse echogenic foci (>1 mm nonlinear areas) and unclassifiable. Histopathological evaluation was performed by two blinded, qualified pathologists.

Results
A total of 114 malignant nodules were included. The average Cohen’s kappa (κ) of three sonographers for the EMF presence was 0.775, indicating substantial agreement. A substantial agreement for PEF with 0.658 κ, only fair agreement for other types of EMF with 0.052 to 0.296 κ were detected. EMF were significantly associated with PB and papillae. PEF had an evident relationship with PB in multivariate analysis. There was a strong positive correlation between the amount of PEF and PB (r = 0.634, P < 0.001).

Conclusions
PEF in PTC mainly correspond to PB on histopathology. Although observation of EMF varies among sonographers, this inconsistency can be reduced by classifying EMF into subgroups and keeping the term ‘PEF’ only for true microcalcifications.
Effects of iodine status on thyroid volume and goiter in children living in an iodine-replete area
Authors: Lee Yun Jeong , Choi Young Hun , Lim Youn-Hee , Kim Bung-Nyun , Kim Johanna Inhyang , Hong Yun-Chul , Park Young Joo , Shin Choong Ho , Cho Sun Wook , Lee Young Ah 
Published: November 2023

Objective
Adequate iodine intake is essential for growing children, and thyroid volume (Tvol) is considered as an indicator of iodine status. We investigated Tvol and goiter using ultrasonography (US) and their association with iodine status in 228 6-year-old children living in Korea.

Methods
Iodine status was assessed using urine iodine concentration (UIC) and categorized as deficient (<100 μg/L), adequate (100–299 μg/L), mild excess (300–499 μg/L), moderate excess (500–999 μg/L), and severe excess (≥1000 μg/L). Tvol was measured using US, and a goiter on the US (goiter-US) was defined as Tvol greater than 97th percentile value by age- and body surface area (BSA)-specific international references.

Results
The median Tvol was 2.4 mL, larger than the international reference value (1.6 mL). The age- and BSA-specific goiter-US rates were 25.9% (n = 59) and 34.6% (n = 79), respectively. The prevalence of excess iodine was 73.7% (n = 168). As iodine status increased from adequate to severe excess, the goiter-US rate significantly increased (P for trend <0.05). The moderate and severe iodine excess groups showed higher risk of goiter-US (adjusted odds ratio (aOR) = 3.1 (95% CI: 1.1–9.2) and aOR = 3.1 (95% CI: 1.2–8.3), respectively; age-specific criteria) than the iodine-adequate group.

Conclusions
Excess iodine was prevalent in Korean children, and their Tvol was higher than the international reference values. Goiter rate was associated with iodine excess, which significantly increased in the moderate and severe iodine excess groups. Further studies are warranted to define optimal iodine intake in children.
16 250 años: murales de pinturas rupestres en el parque nacional natural Serranía de Chiribiquete
Authors: Trujillo Montaña Carlos Eduardo 
Published: November 2023

El Parque Nacional Natural Serranía de Chiribiquete (PNN Serranía de Chiribiquete), lugar de arte rupestre ubicado en la Serranía de La Lindosa (Nueva Tolima, Cerro Azul y el Raudal del Guayabero) en el departamento del Guaviare, Colombia, fue reconocido como patrimonio mixto de la humanidad por parte de la Organización de las Naciones Unidas para la Educación, la Ciencia y la Cultura (Unesco) en el Gobierno del expresidente Juan Manuel Santos, y es una zona que ha sido afectada directamente por el conflicto armado; en su momento, por el grupo guerrillero de las Fuerzas Armadas Revolucionarias de Colombia- Ejército del Pueblo (FARC-EP) y en la actualidad por disidencias residuales del mismo grupo.
El PNN Serranía de Chiribiquete es un lugar sagrado considerado cuna de la humanidad, donde los derechos humanos y el arte van de la mano, que requiere de protección especial debido a la vulnerabilidad a la que se encuentra expuesto por los grupos al margen de la ley, la tala indiscriminada de selva, y el turismo ilegal y sin conciencia de protección. Estas situaciones surgen debido a la necesidad de supervivencia de los colonos del lugar, ya que su principal y única fuente de ingreso en años anteriores dependía de los cultivos ilícitos y el narcotráfico, ignorando que estos son territorios sagrados en los que se encuentran comunidades indígenas que no desean ser contactadas por el resto de la humanidad.
Calidad y Evaluación en los Centros Educativos No Universitarios en Andalucía. Una Adaptación Al Modelo EFQM
Authors: Ramírez Antonia , Lorenzo Esther 
Published: November 2023

La calidad educativa es una meta que ha de alcanzarse en los próximos años en los centros educativos andaluces, pero llegar hasta ella es un camino laborioso. A lo largo de este trabajo analizaremos la relación que se establece entre la calidad educativa, la autonomía de los centros y la evaluación de los mismos; asimismo, realizaremos un recorrido por los distintos planes y proyectos que se han generado en la Comunidad Autónoma de Andalucía en torno a la calidad y la evaluación de los centros educativos no universitarios a lo largo de estos últimos años. Finalmente, nos referiremos al Modelo de Excelencia EFQM, elegido por la Consejería de Educación de la Junta de Andalucía como base de la evaluación de los diferentes centros educativos de la Comunidad.Palabras clave: Calidad educativa, evaluación de centros, EFQM, autonomía de los centros, planes y proyecto. The educational quality is a goal that has to be reached in the next years in the educational centers Andalusian, but to obtain it is a laborious way. Along this work we will analyze the relation that is established between the educational quality, the autonomy of the centers and the evaluation of the same ones; also, we will see the different plans and projects that have been generated in Andalusia concerning the quality and the evaluation of the educational not university centers throughout the latter years. Finally, we will refer to the Model of Excellency EFQM, chosen by the Commission of Education of Andalusia as base of the evaluation of the different educational centers of the Community.keywords: Educational quality, evaluation of centres, EFQM, autonomy of the centers, plans and projects.
Consideraciones Metodológicas y Conceptuales para el Análisis de Predicción del Desempeño Escolar en Base a Indicadores del Contexto Hogareño y Escolar
Authors: Segretin María Soledad , Lipina Sebastián J. , Petetta Daniel Roberto 
Published: November 2023

El presente trabajo propone caracterizar el desempeño escolar de poblaciones de alumnos de nivel primario y secundario por medio del análisis de determinantes sociales y el contexto escolar; e identificar predictores de tal desempeño que contribuyan al diseño de estrategias de intervención. Para realizar los análisis de regresión (identificación de predictores contextuales del desempeño), se diseñaron dos índices de riesgo a partir de variables individuales obtenidas de censos educativos nacionales (Argentina). La selección de variables se efectuó en base a la perspectiva de las necesidades de desarrollo infantil. Los modelos de regresión implementados permitieron identificar perfiles de predicción caracterizados por el aumento del desempeño en matemática y lengua en la medida en que las condiciones de vida y del contexto escolar contempladas mejoraban. La metodología de análisis aplicada permitió identificar la existencia de una situación de inequidad educativa, en la que las áreas identificadas para potenciales intervenciones sugieren contemplar: (a) universalización de acciones protectoras del desarrollo infantil; (b) mejora de la disponibilidad y la calidad de los recursos y prácticas educativas en diferentes contextos (hogar, escuela); (c) capacitación de maestros; y (d) mejora de los sistemas de comunicación entre los distintos actores de las comunidades educativas.Palabras clave: Desempeño escolar, determinantes sociales, inequidad educativa, vulnerabilidad social, factores de riesgo. The aim of the present work is to characterize primary and secondary students' school achievement (language/arithmetic) based on the analysis of social determinants and school environment; and to identify risk factors of performance among social determinants to contribute to the efforts of designining intervention strategies. To carry out the regression analyses for the identification of contextual predictors of school achievement, two risk indexes were designed based on individual variables from national educational data (Argentina). Selection of variables was made based on the perspective of child development needs. The implemented regression models allowed identifying prediction profiles characterized by increasing school achievement as social determinants and school context improved. The applied methodology of analyses allowed identifying the existence of a circumstance of educational inequity, which suggests the need to: (a) universalize protective actions toward child development; (b) improve material and human resources related to educational practices in different contexts (home, school); (c) teachers training; and (d) improve communication systems among the different actors of educational communities.Keywords: School achievement, social determinants, educational inequity, social vulnerability, risk factors.