bluuebunny/crossref_metadata_2025_split huggingface dataset:
Аrginine – biological role, biosynthesis and whey consumption
Authors: Korytko O. O. 
Published: December 2023

The article summarizes actual information about L-arginine (Arg), which is the semi-essential amino acid. L-arginine is classified as an essential amino acid for birds, carnivores and young mammals and a conditionally essential amino acid for adults. L-arginine plays very important role in the plant and animal body metabolism. It metabolically interconvertible with the amino acids proline and glutamate and also is the precursor of a large number of crucial metabolites. It is serves as a precursor for synthesis of molecules of great biological importance, including proteins, L-ornithine, polyamines, agmatine, creatine and urea, which is important in the urea cycle. The main importance of L-arginine is attributed to its role as a precursor for the synthesis of nitric oxide (NO), a free radical molecule that is synthesized in all mammalian cells from L-arginine by NO synthase. NO appears to be a major form of the endothelium-derived relaxing factor. So, L−arginine plays a special role in vascular system, where it is a source of endogenous nitric oxide, which is blood vessels dilator. The use of supplements with L-arginine is appropriate in the prevention and treatment of metabolic diseases. Thanks to relaxation of vascular smooth muscles, it takes part in regulation of blood vessels tone. Treatment by arginine as a medicine improves functions of cardiovascular system. L-Аrginine there is in plant and animal food and in seafood. L-arginine has a wide and varied application such as animal feeding, cosmetology, medical field. In recent years arginine production has been increasing. L−Arginine is obtained by hydrolysis of proteins, with the help of chemical and microbiological synthesis. Microbiological synthesis of L-arginine is the most promising and economically advantageous. Modern microbial technologies use monosubstrates and mixed substrates. Bacteria can synthesize all 20 proteinogenic amino acids, including the nine essential amino acids required for mammalian growth. In general, enzymes involved in the biosynthesis of amino acids are essential for the growth and survival of bacteria. Peat cause great scientific interest. Peat is a natural media for growing symbiotic microorganisms, and has advantages over other types of natural feedstocks. We obtained a peat-based bio-substrate using an inorganic sulfur-containing compound. As a result of bio-substrate composting the content arginine and some other amino asides increased. This bio-substrate was used in resіaches as a feed additive for broiler chickens. Under the action of the feed additive the metabolism in the body of chісkens, growth and live weight gain improved.
Environmental Impacts of Waste Management in the City of Taluqan
Authors: Farkhari Zabihullah , Rahmat Rahmatkhan , Farid Ahmad Farid , Khaleeq Khalilullah 
Published: December 2023

This study aims to find the environmental impacts of waste management within four seasons (spring, summer, autumn, and winter) of the year in Taluqan City. In this research, samples from 100 families during one week noted that dustbin setups for each house and labels like plastics, metals, organics, ashes, diapers, and plastic cans were used to separate waste easily. Household waste generation was analysed using various methods; a questionnaire survey was carried out among 400 householders to assess the current state of waste management in Taluqan City. The result showed that the government has no proper waste management; the residents collect and throw waste into the environment (surface water, vacant lands, streets, agricultural areas, etc.). The average waste generation was 0.903 kg/capita/day for winter, 0.805 kg/capita/day for summer, 0.53 kg/capita/day for spring, and 0.6 kg/capita/day for fall. The percentage of solid waste components in Taluqan City is organic at 60%, glass at 4.2%, metals at 13.25%, plastic and papers at 7.75%, and diapers at 15%. The average generation rate for all seasons is 0.72 kg /capita/day in Taluqan. Based on the respondents, 90 % of households throw their waste into surface water or vacant lands, 75% were interested in receiving information regarding the 3Rs (reduce, reuse, and recycle), 70 % wanted to pay for the collection, 65% wanted to collect from Masjid-to-Masjid, 35% like to be visited house-to-house and 17% were willing for separation of their waste.
Kearifan Lokal Masyarakat Desa Batu Berian dalam Strategi Konservasi Sumber Daya Laut Sebagai Sumber Belajar Biologi
Authors: Kabani Rana , Setiadi Anandita Eka , Sunandar Ari 
Published: December 2023

Kearifan lokal dalam strategi konservasi sumber daya laut merupakan kegiatan masyarakat dalam menjaga ekosistem laut. Beberapa kearifan lokal masyarakat di desa Batu Berian berhubungan dengan strategi konservasi sumber daya laut. Penelitian ini bertujuan untuk menganalisis kearifan lokal masyarakat desa Batu Berian dalam strategi konservasi sumber daya laut yang dapat dijadikan sumber belajar pada materi Biologi. Penelitian menggunakan pendekatan kualitatif dengan metode etnografi. Teknik pengumpulan data menggunakan wawancara, angket, dan dokumentasi. Hasil penelitian kearifan lokal masyarakat desa Batu Berian dalam strategi konservasi sumber daya laut terdiri atas 6 pantangan yaitu, tundok kuali, buang air besar dan kecil sembarangan, buang ketupang di malam hari, merusak bakau, tujoh pangsek pakai besi, dan nyelup pinggon setelah makan di laut. Potensi kearifan lokal masyarakat desa Batu Berian sesuai dengan materi pokok SMP kelas VII dan SMA kelas X yaitu materi pencemaran lingkungan dan perusakan lingkungan. Kearifan lokal masyarakat desa Batu Berian dalam strategi konservasi sumber daya laut mendapat kategori sangat baik dengan skor rata-rata persentase per aspek yaitu 98,33%. Disimpulkan, secara keseluruhan bahwa kearifan lokal masyarakat desa Batu Berian memiliki potensi sebagai sumber belajar
Jornadas de Ciencia y Tecnología (JorCyTec 2023)
Authors: Concordia UTN Facultad Regional 
Published: December 2023

Las Jornadas de Ciencia y Tecnología de la Facultad Regional Concordia de la Universidad Tecnológica Nacional se realizan con el objetivo de difundir los resultados de los proyectos de investigación desarrollados en la Facultad y compartir temas de actualidad con estudiantes, docentes, investigadores, profesionales del sector productivo y público en general. Las Jornadas son de acceso libre y gratuitas.
Comité Organizador
Ing. Electr. Marcelo Arlettaz
Ing. en Alim. Alfonsina Alzogaray
Ing. Ind. Camila Benitez
Ing. Civil Marcos Blanc
Lic. Fabricio Bonato
Mg. Lic. Laura Gervasi
Ing. Eléctr. Matín Girardo
Ing. Civil Emilia Medina
Ing. Civil Alberto Palacio
Ing. Civil Andrea Pereyra
Ing. Mec. Pablo Quantín
Dra. Natalia Tesón
Lic. Adm. Rural Sebastián Trupiano
Lic. Adm. Rural Gabino Vale

Comité Académico
Prof. Carolina Chacón
Dr. Carlos María Chezzi
Dr. Omar Faure
Dra. Eugenia Garat
Mg. Federico Larocca
Dra. Viviana Rougier
Dr. Fabián Tissoco
Dr. Germán Scattone
Dr. Ricardo Rosales
Clinical features of oncohematological diseases in twins (literature review)
Authors: Radjabova G. A. , Valiev T. T. 
Published: December 2023

Relevance. According to the World Health Organization, the most common oncological diseases in childhood are hemoblastoses. In particular, acute leukemia ranks the first in the structure of malignant tumors, non-Hodgkin’s lymphomas – the third, Hodgkin lymphoma – the fifth in children aged 0 to 19 years. There is no convincing evidence of the inheritance of these diseases, but nevertheless, the literature describes cases of the development of the same disease with the same immunophenotype within the same family in mono- or dizygotic twins, which is one of the proofs of the persistence of preleukemic cells and the possibility of their migration from one twin to another during the antenatal development. These data allow us to study the features of oncogenesis in leukemia in twins, in particular monozygotic twins: the timing of tumor development, clinical features and molecular biological characteristics, as well as the response to therapy.Aim. To study the clinical and molecular-genetic features of hemoblastoses in twins.Materials and methods. When writing a literature review, we analyzed data in specialized medical databases PubMed, Scopus, Web of Science with the very first descriptions of the manifestations of tumors of the hematopoietic system in monozygotic twins from 1964 to 2023.Results. In the course of writing this literature review, we confirmed that the genetic component plays a significant role in the development of hemoblastoses. Studies on twins reveal genetic mutations that predispose to the development of malignant blood tumors, which in turn opens up new opportunities for the early diagnosis of hemoblastoses. The twin method allows for comparative clinical trials of different treatment approaches, which help to choose the optimal therapy and improve the prognosis of diseases.
α-Lipoic acid as an ingredient of specialized food product and dietary supplement
Authors: Kodentsova V. M. , Risnik D. V. 
Published: December 2023

A review of the literature in recent years was carried out using the RSCI, Google Scholar, Pubmed, and ResearchGate databases.The purpose of the review was to assess the content of α-lipoic acid (ALA) in foods and compare the doses allowed for use in dietary supplements and specialized food products with doses that provide a clinical effect. ALA or thioctic acid is synthesized in the organism and is also found in foods in free oxidized and reduced form, bound to proteins by hydrogen bonds, as well as covalently bound to lysine residues (lipoyl-lysine) in proteins, which complicates the analytical determination and reduces the bioavailability of this vitamin-like substances. Various methods for determining the natural content of individual forms (ALA and lipoyl-lysine) and their total content in food products have been described. The content of free ALA in 100 g of raw products of animal origin varies from 0.22 to 1.35 mg, of plant origin – from 0.22 to 2.04 mg. Losses during heat treatment reach 77–92%. Lipoyl–lysine content ranged from 2.11–3.99 µg/g heart, 0.56–1.17 µg/g liver, 0.71–1.40 µg/g kidney, while ALA amounts ranged from 0.22 up to 0.55 µg/g heart, from 0.38 to 0.51 µg/g liver. It is difficult to estimate the dietary intake of the total amount of all forms of ALA due to differences in extraction and detection methods. According to the domestic regulatory framework, the adequate level of ALA consumption for adults is 30 mg/day, the upper permissible level of daily consumption for adults as part of specialized food products (SFP), preventive and therapeutic nutrition and dietary supplements is 100 mg/day. ALA is often included in multicomponent dietary supplements and SPP in doses from 15 mg to 100 mg. A positive effect when taken for 10 or more weeks on lipid and carbohydrate metabolism, as well as other clinical effects in patients, is observed when taking ≥ 600 mg of ALA per day, which is significantly higher than the doses allowed for inclusion in the SFP.
Perancangan dan Pembuatan Sistem Informasi Manajemen Aset TI (Studi Kasis di PT. Tiga Serangkai Pustaka Mandiri Surakarta)
Authors: Herwin Zakiyah  , Eva Safitri  
Published: December 2023

Asset TI merupakan salah satu sumber daya yang paling penting dalam sebuah perusahaan. Oleh karena itu, pengelolaan asset khususnya asset TI harus diatur secara terstruktur dan sistematis. Tujuan penelitian ini adalah membuat Sistem Informasi Manajemen Aset Tekbologi Informasi yang sesuaidengan kebutuhan PT TSPM. Sistem informasi manajemen asset TI dirancang untuk mengelola asset TI dalam siklus hidupnya, mulai dari inventarisasi asset, maintenance asset, rehabilitasi asset dan penghapusan asset. Dalam sistem yang dikembangkan, siklus hidup asset TI dapat termonitor secara jelas, sehingga dapat mendukung proses pengambilan keputusan bagi pihak manager MIS dan pihak lain yang terkait dengan manajemen asset TI, khususnya dalam hal analisis kebutuhan asset TI, procurement asset TI dan optimalilsasi aset TI. Metode pengembangan yang digunakan adalah metode SDLC yang terdiri dari beberapa tahapan, meliputi tahap planning, analisis, desain dan implementation. Sistem yang dikembangkan berbasis web dengan dilengkapi fitur Help Desk. Fitur ini berfungsi sebagai media komunikasi dan informasi incident yang dilaporkan oleh user kepada staff TI apabila terjadi permasalahan pada perangkat TI. Dengan demikan, penanganan incident menjadi cepat, ketersediaan aset dapat meningkat dan biaya maintenance relatif lebih rendah.
Harnessing axonal transport to map reward circuitry: Differing brain-wide projections from medial prefrontal cortical domains
Authors: Bearer Elaine L. , Medina Christopher S. , Uselman Taylor W. , Jacobs Russell E. 
Published: December 2023

Graphical AbstractTract tracing after MnCl2 stereotactic intracerebral injection is performed by time-lapse MRI in living mice, based on harnessing the intracellular axonal transport machinery, kinesin and microtubules. Volumes of statistically significant, Mn(II)-dependent, image enhancements report on distal accumulations brain wide that can be measured segment-wise for statistical comparisons of the relative strength of the projection contacts. Targets of neuronal projections from the medial prefrontal cortex differ between anterior cingulate (ACA, red) and infralimbic-prelimbic (IL/PL, blue) areas. While neurons in ACA project to central amygdala, posterior hypothalamic regions, periaqueductal gray, dorsal raphe, and locus coeruleus; those in IL/PL project to basolateral amygdala, anterior hypothalamic subsegments, central superior raphe and pons.
Emotion recognition with multi-modal peripheral physiological signals
Authors: Gohumpu Jennifer , Xue Mengru , Bao Yanchi 
Published: December 2023

IntroductionHealthcare wearables allow researchers to develop various system approaches that recognize and understand the human emotional experience. Previous research has indicated that machine learning classifiers, such as Support Vector Machine (SVM), K-Nearest Neighbors (KNN), and Decision Tree (DT), can improve the accuracy of physiological signal analysis and emotion recognition. However, various emotions can have distinct effects on physiological signal alterations. Therefore, solely relying on a single type of physiological signal analysis is insufficient for accurately recognizing and understanding human emotional experiences.MethodsResearch on multi-modal emotion recognition systems (ERS) has commonly gathered physiological signals using expensive devices, which required participants to remain in fixed positions in the lab setting. This limitation restricts the potential for generalizing the ERS technology for peripheral use in daily life. Therefore, considering the convenience of data collection from everyday devices, we propose a multi-modal physiological signals-based ERS based on peripheral signals, utilizing the DEAP database. The physiological signals selected for analysis include photoplethysmography (PPG), galvanic skin response (GSR), and skin temperature (SKT). Signal features were extracted using the “Toolbox for Emotional Feature Extraction from Physiological Signals” (TEAP) library and further analyzed with three classifiers: SVM, KNN, and DT.ResultsThe results showed improved accuracy in the proposed system compared to a single-modal ERS application, which also outperformed current DEAP multi-modal ERS applications.DiscussionThis study sheds light on the potential of combining multi-modal peripheral physiological signals in ERS for ubiquitous applications in daily life, conveniently captured using smart devices.
Factors influencing serum calcium levels and the incidence of hypocalcemia after parathyroidectomy in primary hyperparathyroidism patients
Authors: Mu Yongliang , Zhao Yishen , Zhao Jiannan , Zhao Qi , Zhang Yushuai , Li Yang , Kou Jiedong , Dionigi Gianlorenzo , Bian Xuehai , Sun Hui 
Published: December 2023

BackgroundParathyroidectomy (PTX) is an effective treatment for primary hyperparathyroidism (PHPT) patients. Postoperative hypocalcemia is a common complication after PTX. This study aimed to analyze the factors influencing serum calcium levels and the incidence of hypocalcemia after parathyroidectomy in primary hyperparathyroidism patients.MethodsThe retrospective study included 270 PHPT patients treated with PTX and collected their demographic and clinical information and their laboratory indices. Factors influencing serum calcium levels and hypocalcemia after PTX in PHPT patients were analyzed using univariate and multifactorial analyses.ResultsFirst, in patients with normal preoperative serum calcium levels (2.20–2.74 mmol/L), the higher the preoperative alkaline phosphatase and serum phosphorus levels, the lower the postoperative serum calcium levels. Furthermore, the higher the preoperative serum calcium levels and the accompanying clinical symptoms, the higher the postoperative serum calcium levels. Low preoperative serum calcium levels were shown to be a risk factor for postoperative hypocalcemia (OR=0.022), and the optimal preoperative serum calcium threshold was 2.625 mmol/L (sensitivity and specificity were 0.587 and 0.712, respectively). Second, in the mild preoperative hypercalcemia group (2.75-3.00 mmol/L), the older the patient, the higher the preoperative and postoperative serum calcium levels, the higher the postoperative serum calcium; the lower the alkaline phosphatase and calcitonin levels, the higher the postoperative serum calcium levels. On the other hand, the younger the patient was, the more likely hypocalcemia blood was (OR=0.947), with an optimal age threshold of 47.5 years (sensitivity and specificity were 0.543 and 0.754, respectively). Third, in the preoperative moderate to severe hypercalcemia group (&gt;3.0mmol/L), patients undergoing a combined contralateral thyroidectomy and a total thyroidectomy had low postoperative serum calcium levels.ConclusionPatients with different preoperative serum calcium levels had various factors influencing their postoperative serum calcium levels and postoperative hypocalcemia, which facilitated the assessment of their prognosis.
The potential of multiapartment rooftop PV systems as citizen’ energy communities in Latvia
Authors: Lebedeva Kristina , Borodinecs Anatolijs , Odineca Tatjana 
Published: December 2023

Electricity generation from photovoltaic (PV) in Latvia is currently below the necessary capacity required to contribute to achieving climate neutrality by 2050. However, photovoltaic offer households and companies the opportunity to align their electricity consumption with environmental goals while supporting the European Green Deal objectives. In recent years, there was a growing interest in the installation of photovoltaic microgenerators in Latvia. By June 2023, the total number of households microgenerators connected to the grid has reached 15,000, boasting a collective production capacity exceeding 120 MW. This significant increase is in stark contrast to the situation 5 years ago when Latvia had a mere 3 MW of photovoltaic capacity. Several factors contributed to this growth, including a surge in electricity prices, at times surging more than tenfold, and the implementation of renewable energy (RE) use support measures to facilitate the acquisition of RE systems. Furthermore, 2023 witnessed numerous amendments to Latvia’s energy policy documents and the introduction of the concept of citizen energy communities (CEC), indicating a growing emphasis on harnessing solar energy potential in the country. However, it remains crucial to base these endeavors on accurate, economically viable information regarding solar technologies, their costs and their anticipated long-term outcomes. This manuscript aims to provide an overview of the grid-connected potential of rooftop photovoltaic systems within a Latvian urban setting. Through extensive research, a model has been developed, employing a thoroughly tested simulation program for evaluating the generation capacity of photovoltaic systems. This model considers real electricity consumption data, the existing infrastructure and economic factors. The findings affirm the technical and economic viability of urban rooftop photovoltaic systems within the Latvian context. It has been established that the implementation of such citizen energy communities energy systems holds significant potential. These systems have the potential to be a promising solution for future electricity generation, addressing some of the demands while relieving strain on external power grids. However, the full potential can only be realized with improved infrastructure, and the system’s profitability is heavily contingent on market dynamics and political conditions. This study may also be applicable to other photovoltaic systems facing similar climate conditions.
Understanding the characteristics of agricultural land transition in Thiès region, Senegal: an integrated analysis combining remote sensing and survey data
Authors: Faye Bonoua , Du Guoming , Li QuangFeng , Sané Tidiane , Mbaye Edmée , Zhang Rui 
Published: December 2023

Adopting an integrated analysis is a prominent tool for a coherent understanding of the characteristics of agricultural land transition in developing countries. Hence, using an integrated analysis combining remote sensing and survey data, this investigation aimed to understand the spatial-temporal distribution and intensity of agricultural land transition in Senegal through a case study in the Thiès region. Through ArcGIS and ENVI software, we interpreted the land use types from 2000 to 2020 and the transfer matrix method used to characterize the agricultural land transition. Then, the Pearson correlation coefficient is used to determine the intercorrelation between natural and socio-economic driving factors of agricultural land use. The main results show that agricultural land transition was about −588.66 km2. Grassland was the most crucial land morphology to participate in this transition. Regarding spatial distribution, the highest net transition of agricultural land was recorded in Mont-Rolland (33.22%) and the lowest in Sandiara commune (−41.73%). The temporal distribution is represented in Koul, with −0.35%, and Mont-Rolland commune, with 24.84%. The intensity of agricultural land transition was high in Malicounda commune, at 11.34%. The social survey also shows a strong relationship between wind erosion and land salinity (0.971) as potential driving factors that may induce agricultural land transition. Based on an integrated method, the contribution of this study enhances the theoretical approach and methodology for assessing the mean potential driving factors in developing countries such as Senegal. Consequently, agricultural land transition in Thiès region was complex and must be implemented with complex and comprehensible policy solutions.