bluuebunny/crossref_metadata_2025_split huggingface dataset:
Androgen deprivation therapy plus apalutamide as neoadjuvant therapy prior radical prostatectomy for patients with unresectable prostate cancer
Authors: Wei Yongbao , Zhang Ruochen , Zhong Dewen , Chen Zhensheng , Chen Gen , Yang Minggen , Lin Le , Li Tao , Ye Liefu , Chen Lili , Zhu Qingguo 
Published: October 2023

Whether neoadjuvant therapy confers a survival benefit in advanced prostate cancer (PCa) remains uncertain. The primary endpoints of previous retrospective and phase II clinical studies that used neoadjuvant therapy, including androgen deprivation therapy combined with new-generation androgen receptor signaling inhibitors or chemotherapy, were pathological downstaging, progression-free survival, prostate-specific antigen relief, and local symptom improvement. To the best of our knowledge, no studies have explored the efficacy and safety of neoadjuvant therapy in improving the surgical resection rate in cases of unresectable primary tumors of PCa. We first designed this retrospective study to evaluate the potential value of apalutamide as neoadjuvant therapy in improving the resectability rate of radical prostatectomy (RP). We initially reported 7 patients with unresectable primary lesions who underwent neoadjuvant apalutamide treatment for a median of 4 months, and all of them successfully underwent RP treatment. Our study supported apalutamide as neoadjuvant therapy, which helped improve RP’s success rate and did not significantly increase perioperative complications, and the neoadjuvant therapy was controllable. Our findings’ clinical value and benefit for survival still need further clinical research to confirm.
Magnetic resonance imaging for diagnosis of suspected neurogenic thoracic outlet syndrome-a systematic scoping review
Authors: Szaro Pawel , Suresh Rohan , Molokwu Brian , Sibala Dhiraj Raju , Mendiratta Dhruv , Chu Alice , McGrath Aleksandra 
Published: October 2023

Background: Neurogenic Thoracic Outlet Syndrome (nTOS) is a rare pathology caused by dynamic conditions or compression of neurovascular structures in the thoracic outlet region. nTOS can be difficult to diagnose due to nonspecific symptoms and magnetic resonance imaging (MRI) techniques are increasingly used to aid the diagnosis and surgical planning. This scoping systematic review explores how MRI is used for diagnosing nTOS and summarizes details of published MRI protocols.Methods: A systematic screening of PubMed, Cochrane, Web of Science, and CINAHL databases using PRISMA-IPD guidelines was conducted in September 2022 to include full-text English papers on MRI and nTOS. Inclusion criteria involved studies describing MRI protocols for the diagnosis of TOS, with a focus on the imaging sequences and protocols.Results: 6289 papers were screened to include 28 papers containing details of MRI protocols. The details of MRI protocols in the analyzed articles were incomplete in all studies. Most authors used 1.5T systems and included T1 and T2-weighted sequences. Most studies applied fat suppression, mainly with STIR. Positioning of the arm differed between studies, including neutral, hyperabducted and abducted and externally rotated positions.Conclusion: Our review highlights a prevalent lack of detailed MRI protocol documentation for brachial plexus. Authors primarily rely on conventional 1.5T systems, employing standard T1 and T2-weighted sequences. The adoption of novel MRI sequences is notably lacking, and fat suppression techniques predominantly adhere to older methods as STIR. There is a clear imperative for authors to provide more comprehensive reporting of the MRI protocols utilized in their studies, ultimately enhancing comparability and clinical applicability. Establishing clear protocol reporting guidelines is crucial to allow for comparison between studies.
Discrepancy of eye injuries in mechanism, clinical features, and vision prognosis by different causative sports
Authors: Zhang Ying , Jia Hongzhen , Kang Xin , Yang Qinghua , Ying Jun , Wu Qiong , Zheng Zhong , Zhang Hongtao 
Published: October 2023

ObjectiveTo investigate the epidemiological and clinical characteristics of sports-related eye injuries in China, as well as how they differ depending on the sport or other specific factor that caused them.MethodsConsecutive medical records from 2015 to 2019 of sports-related eye injuries from a standardized database in nine tertiary referral hospitals in China were retrospectively reviewed and analyzed.ResultsA total of 377 eyes in 376 inpatients (mean age, 22.5 ± 7.3 years; men:women 15.4:1) were included. Soccer (46.8%), basketball (27.1%), and badminton (16.8%) were the top three sports that caused injury. Ball strikes (74.7%), physical collision (13.8%), and racket/equipment beating (9.0%) were the common specific causes of injury. Blunt force injuries (95.8%) and close globe injuries (95.1%) accounted for the majority of injuries. Open globe injuries occurred more in basketball (8.3%) than in other sports, mainly due to physical collision (12.8%) and racket/equipment beating (11.8%). Basketball (13.4%) or physical collision (21.3%) caused Zone I injuries more frequently than other sports. Soccer (60.5%) and basketball (54.6%) caused more injuries to the posterior segment of the eyeball than other sports, mainly due to ball strikes (96.6%). Badminton (69.8%) and racket beating (61.8%) caused more Zone II globe injuries than other sports. In badminton, the percentage of hyphema (85.7%), the most typical symptom of eye damage, and ultimate visual acuity (VA) ≥20/40 (88.9%) was the greatest. A final low vision score of (≤4/200) was observed in 10.6% of all participants, including three participants who had an eye removed due to rupturing. The final VA was positively correlated with the presenting VA (r = 0.421).ConclusionSports can lead to high proportions of ocular contusion injury and low vision. VA prognosis is closely related to initial VA following ocular sports trauma, which is directly determined by the causative sports and/or the specific causes. Effective eye protection is imperative to avoid or reduce visual impairments of sports participants.
Civic engagement and mental health trajectories in Norwegian youth
Authors: Wiium Nora , Kristensen Sara Madeleine , Årdal Elisabeth , Bøe Tormod , Gaspar de Matos Margarida , Karhina Kateryna , Larsen Torill Marie Bogsnes , Urke Helga Bjørnøy , Wold Bente 
Published: October 2023

IntroductionApplying variable-centered analytical approaches, several studies have found an association between civic engagement and youth mental health. In the present study, we used a person-centered approach to explore whether civic engagement was related to optimal trajectories of mental health compared to other trajectories. We also examined how sociodemographic factors, such as socioeconomic status (SES), gender and age were related to youth mental health trajectories.MethodsOur sample comprised 675 students (aged 16–22) who had participated in three waves of data collection (Mage = 18.85, SD = 0.55; 43% males) in the COMPLETE project, a cluster-randomized controlled trial that involved Norwegian upper secondary schools.ResultsThe results revealed three trajectories of mental health (reflecting a combination of mental distress and mental well-being): optimal, intermediate, and sub-optimal. Contrary to our expectations, higher levels of civic engagement were not related to the optimal trajectory of mental health vs. other trajectories. However, we found that students who reported higher levels of SES and males were more likely to follow the optimal trajectory compared to other trajectories.DiscussionWhile the findings on civic engagement could be due to our measurement’s inability to capture the concept of “dugnad,” a well-established civic activity in the Norwegian society, the findings regarding the influence of SES and gender suggest that there is still more work to be done concerning the assessment and advancement of factors that can address mental health inequalities across SES and gender.
Blood donation practice and its associated factors among Polish population: secondary data analysis
Authors: Siekierska Barbara , Tomaszek Lucyna , Kurleto Paulina , Turkanik Edyta , Mędrzycka-Dąbrowska Wioletta 
Published: October 2023

IntroductionBlood transfusion is an intervention widely used in therapeutics (e.g., in the perioperative period), thus, knowledge about factors associated with blood donation is important. The aim of this study was to investigate the impact of sociodemographic factors, personal values and life satisfaction on blood donation in Poland.MethodsSecondary analysis of data. A multiple logistic regression was carried out to assess the relationship between sociodemographic factors, life satisfaction (Satisfaction with Life Scale), personal values (Personal Values List) and blood donation.ResultsOf the 770 respondents aged 18–65 years, 262 respondents (34%) donated blood at least once in their lives. Respondents who believed that blood donation is safe (OR = 1.71; Cl95%: 1.20 to 2.43), were male (OR = 1.47; Cl95%: 1.26 to 1.72), married (OR = 1.31; Cl95%: 1.11 to 1.54) and those with high school education (OR = 0.81; Cl95%: 0.66 to 0.99) were more often blood donors.ConclusionPerceived blood donation safety and sociodemographic factors such as gender, marital status, and education level may influence blood donation. Health education is necessary to increase knowledge and shape positive attitudes toward blood donation among the society.
Assessing Water Resource Carrying Capacity and Sustainability in the Cele–Yutian Oasis (China): A TOPSIS–Markov Model Analysis
Authors: Jia Guangwei , Li Sheng , Jie Feilong , Ge Yanyan , Liu Na , Liang Fuli 
Published: October 2023

This study employs the Driving Force–Pressure–State–Response (DPSR) framework to establish an evaluation index system for the water resource carrying capacity (WRCC) in the Cele–Yutian Oasis (China). Utilizing the TOPSIS and obstacle degree models, we analyze the trends in the WRCC and its main hindrance factors in the Cele–Yutian Oasis from 2005 to 2020. Additionally, we employ the Markov model to investigate the dynamic changes in the land use types. The findings reveal that the most unfavorable WRCC status occurred in 2007, with a Grade IV rating (a mild overload). By 2020, the WRCC improved to a Grade III rating (critical), indicating a positive trajectory. However, persistent challenges for water resources remain, with a prolonged critical state. Over the past 15 years, the grassland area has decreased by 15.18%, and the forest area has decreased by 50%. The dynamic degree of grassland, forests, and water bodies is negative, signifying shifts to other land types, with water bodies undergoing the most significant change at −10.16%. Based on the outcomes of these two models, we propose regionally tailored measures to support sustainable development. These research results provide a scientific foundation for optimal water resource allocation and sustainable development in the Cele–Yutian Oasis Economic Belt.
PERLINDUNGAN TERHADAP LESSEE USAHA DALAM PERJANJIAN SEWA GUNA SEBAGAI KONTRAK BAKU
Authors: Sudjana Sudjana - 
Published: October 2023

This study aims to determine the clarity of existence (leasing) in agreement and leasing law in the perspective of standard agreements.The method of approach is juridical normative and the data is analyzed in a qualitative normative way to produce descriptive data based on the study of statutory norms.The results of the study show that leasing in treaty law has 2 (two) financing categories, namely finance lease (lease with option rights) and operating lease (lease without option rights). In contract law, the operating lease has the aspect of a lease agreement while the finance lease is more in line with the aspect of buying and selling, but each of these aspects compared to the financing category still has a difference. Whereas leasing in the standard agreement perspective applies in accordance with freedom of contract vide Article 1320 jo Article 1338 of the Civil Code as long as it does not lead to eliminating the responsibility of the business actor (exenorasi classula), but considering the lease agreement unilaterally determined by the lessor, the position of the lessee is still weak legal protection through legal action that can be carried out, for example filing a claim for compensation, costs and interest
UTILIZING INFORMATION TECHNOLOGY TO ENHANCE THE CAPACITY AND EFFICIENCY OF CONTROL SYSTEM FOR TRANSMISSIBLE DISEASES IN HO CHI MINH CITY
Authors: Nguyen Dung Tri , Nguyen Thu Vu Minh , Le Nga Hong , Tran Huyen Thi Ai , Le Tuyet Thi Anh , Van Thinh Thi Ngoc , Le Minh Truong , Tran Tuan Anh , Hoang Long Dai Thien , Pham Khuong Quoc , Khuu Canh Minh , Truong Tuan Quoc , Phan Duy Le Thai 
Published: October 2023

A research and development study was conducted from September 2020 to April 2023 involving 9 hospitals, 24 district health centers and 319 commune health stations. The main objective of the study was to establish,refine, and update a system for controlling directly transmitted diseases in Ho Chi Minh City, as well as assess its practical implementation. Before the system update, the study identified limitations in disease surveillance, particularly in monitoring cases that were not examined or treated at hospitals. The existing reportingmechanisms also resulted in incomplete disease data, with subpar data quality due to delays and inadequate processing of reported cases. Considering the prevailing circumstances, management requirements and usage needs, the system underwent enhancements and integrated GIS capabilities. This allowed healthcare personnel to swiftly and accurately identify disease cases, determine contacts, establish epidemiological zones, tracetransmission chains, and monitor the implementation of control measures. The improved control system has been successfully implemented, ensuring effective management of community-based hand, foot, and mouth disease. Additionally, the system demonstrates the potential for broader applicability in managing other directly transmitted diseases.
BIOELECTRICITY OF COCOA POD WASTE AS A SUBSTRATE IN A DOUBLE CHAMBER MICROBIAL FUEL CELL
Authors: Fitriana Fitriana , Auliq M A'an , Akbar Faisal , Mubarok Zidny 
Published: October 2023

Currently, the utilization of cocoa pod has not been maximized, resulting in waste and foul odors that disturb the environment. However, cocoa pod contain a relatively high amount of cellulose compounds that serve as an energy source or nutrition for bacteria to carry out metabolic activities, thus holding the potential to be used as a substrate in microbial fuel cells (MFC). Based on this, the aim of this research is to investigate the bioelectricity generated by a MFC using cocoa pod husk as a substrate, including voltage, current, and power density, in order to determine the potential of cocoa pod husk waste as an electrical energy source. In this study, a double chamber MFC consists of an anode chamber with copper electrodes and a cathode chamber with zinc electrodes, separated by a salt bridge. The bacteria used were Saccharomyces cerevisiae, and the substrate was made from cocoa pod husk waste. Bioelectricity testing involved measuring the voltage, current, and power density produced by the MFC over several minutes. The measurement results for maximum voltage, maximum current generated, and maximum electrical power (at 6 days) from the reactor were as follows: 36.0 mV, 0.19 mA, and 456 mW/m2, respectively.
On the analysis of sociodynamics of student youth competences in the sphere of Internet technologies and safety of network behavior
Authors: Dolmatov D. A. 
Published: October 2023

The article analyzes the sociodynamics of student youth competences, in particular future lawyers, in the sphere of information technologies and security of network behavior in the conditions of activation of destructive network influences during the special military operation of Russia on the territory of Ukraine. The relevant competencies of students were analyzed in the framework of systematic, purposeful mastering of them according to the results of the entrance and final questionnaire in the form of self-analysis. In the process of the research the following tasks were solved: (1) study of the sociodynamics of network behavior of young users, their knowledge, competencies, attitudes, specific actions and deeds that affect the physical and psychological state in the conditions of interaction in the virtual environment and the use of digital technologies; (2) analyzing the knowledge about the risks of destructive effects of using various Internet resources and content, studying their readiness to counteract negative network influence in modern conditions; (3) analyzing the correlation of the obtained data with the analytics published on the Internet in 2020–2022 based on the results of sociological surveys on similar topics.As the surveys have shown, in order to form safe online behavior of young people on the Internet, minimize the risks of destructive network influence, and ensure information security, it is important to initially and systematically instill the skills of competent online behavior in children, adolescents and young users at all stages of their development and education. It is necessary to teach them to correctly define the boundaries of reliability and misinformation, to ensure the mastery of knowledge about the basics of information security, to form and consolidate skills and competencies to apply the acquired knowledge, including critical thinking, and to counteract destructive network influences. These tasks are especially relevant in the current socio-political environment of special military operation and intensification of information warfare.
Penetrating the Silence: Data Exfiltration in Maritime and Underwater Scenarios
Authors: Cantelli-Forti Alessandro , Colajanni Michele , Russo Silvio 
Published: October 2023

<p>The risk of data exfiltration remains a concern, even when the connectivity of the victim system is limited or the domain is physically isolated. This paper delves into the unique challenges associated with data exfiltration in surface and submarine naval scenarios in the absence of persistent data connections. It explores contexts where attacks through the supply chain can pose a serious risk even if the compromised hardware or software is not connected to any network or even (apparently) switched off. The attacks exploiting vulnerabilities in some components of the supply chain can serve as a conduit for data exfiltration. This study aims to enhance the overall security posture of maritime systems by identifying possible exposures and mitigating the risk of data exfiltration and covered channel attacks. </p>
Monitoring of Tree Fall Incidents using airborne LiDAR, Stereo Imagery, and Sentinel-2 Data
Authors: Alibakhshi Sara 
Published: October 2023

<p>This study focuses on evaluating the capability of optical satellite data in monitoring trees with the potential to cause damage. The study focuses on the application of very high-resolution optical satellite data, specifically Pléiades and SkySat imagery, as a viable alternative to airborne LiDAR for monitoring tree fall risks. The comparative analysis of height estimations from optical satellite data against airborne LiDAR data unveils valuable information on adopting efficient strategies for managing vegetation risks, particularly those impacting power transmission systems. The outcomes of our research contribute substantially to ongoing initiatives aimed at developing vegetation management strategies along powerlines, offering valuable information for decision-makers involved in assessing and mitigating risks associated with tree falls </p>
Unlocking the Power of Reconfigurable Intelligent Surfaces: From Wireless Communication to Energy Efficiency and Beyond
Authors: Pereira de Figueiredo Felipe Augusto 
Published: October 2023

<p>Reconfigurable Intelligent Surfaces (RIS) are a class of metamaterials that have gained significant attention in recent years due to their potential to revolutionize wireless communication, sensing, and imaging technologies. RISs consist of a planar array of closely spaced, subwavelength-sized elements that can manipulate electromagnetic waves in a controllable manner. By reconfiguring the geometry, material properties, or phase of individual elements on the RIS, the surface can be customized to meet specific application requirements. </p>
<p>RISs can potentially improve wireless communication by creating virtual channels, reducing interference, and improving overall quality. They can also enhance the efficiency of energy harvesting systems and improve sensing and imaging technologies by manipulating the propagation and scattering of electromagnetic waves. Additionally, RIS could be used to increase privacy and security by selectively blocking or allowing certain frequencies of electromagnetic waves. </p>
<p>In this article, we provide a brief history of the development of RIS and discuss the design and fabrication of RIS structures. We also explore the potential applications and benefits of RIS technology, including improved wireless communication, enhanced energy efficiency, advanced sensing and imaging, and increased privacy and security. Finally, we highlight some of the current research challenges and future directions for RIS technology. Overall, RISs hold great promise for advancing a wide range of technologies and applications, and we expect to see many exciting developments in this area in the future.</p>
A New Anisotropic Driving Force Model for SiC Device Simulations
Authors: Jin Seonghoon , Lee Kyungmin , Choi Woosung , Park Chulwoo , Yi Shinwook , Fujii Hiroki , Yoo Jaehyun , Park Yonghee , Jeong Jaehoon , Kim Dae Sin 
Published: October 2023

<p>We present a new anisotropic driving force model to compute the anisotropy of the mobility and impact ionization rate in TCAD simulations of SiC devices. We derive the model from the relationship between the mobility, driving force, and carrier heating, where the obtained driving force along the c-axis and that perpendicular to the c-axis depend on the gradient of the quasi-Fermi potential and the mobility anisotropy factor (the mobility ratio along the perpendicular direction to that along the c-axis). Since mobility also depends on the driving force, we solve for the mobility anisotropy factor to determine the anisotropic mobility and driving force together. We also propose a new interpolation scheme to consider the anisotropy of the impact ionization rate using the derived anisotropic driving force. We compare the present model with the existing models in the commercial simulator and demonstrate its applicability to the simulation of a 4H-SiC vertical power MOSFET device. </p>