bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fine‐needle aspiration diagnosis of plasmacytoma presenting as breast masses in a patient on estrogen therapy for prostate cancer
Authors: Vetto John T. , Beer Tomasz M. , Fidda Nisreen , Ham Bruce , Jimenez‐Lee Ricardo , Schmidt Waldemar 
Published: November 2004

AbstractWe describe a 79‐yr‐old man with a history of androgen‐independent metastatic prostate cancer treated with exogenous estrogens presenting with bilateral breast masses associated with bilateral axillary lymphadenopathy. Although the findings on physical examination with the concomitant history of estrogen therapy for metastatic prostate cancer raised the clinical suspicion of breast cancer, fine‐needle aspiration (FNA) cytology identified the lesions as multiple myeloma. Diagn. Cytopathol. 2004;31:417–419. © 2004 Wiley‐Liss, Inc.
Developing a brain specialized for face perception: A converging methods approach
Authors: de Haan Michelle , Humphreys Kate , Johnson Mark H. 
Published: November 2004

AbstractAdults are normally very quick and accurate at recognizing facial identity. This skill has been explained by two opposing views as being due to the existence of an innate cortical “face module” or to the natural consequence of adults' extensive experience with faces. Neither of these views puts particular importance on studying development of face‐processing skills, as in one view the module simply comes on‐line and in the other view development is equated with adult learning. In this article, we present evidence from a variety of methodologies to argue for an “interactive specialization” view. In this view, orienting tendencies present early in life ensure faces are a frequent visual input to higher cortical areas in the ventral visual pathway. In this way, cortical specialization for face processing is an emergent product of the interaction of factors both intrinsic and extrinsic to the developing child. © 2002 Wiley Periodicals, Inc. Dev Psychobiol 40: 200–212, 2002. DOI 10.1002/dev.10027
Physiological and neuropsychological correlates of approach/withdrawal tendencies in preschool: Further examination of the behavioral inhibition system/behavioral activation system scales for young children
Authors: Blair Clancy , Peters Rachel , Granger Doug 
Published: November 2004

AbstractThis study examined a parent‐report version of the Behavioral Inhibition System/Behavioral Activation System (BIS/BAS) scales, a measure of approach–withdrawal motivation, in 170 children between the ages of 3 to 5 years attending Head Start programs. Physiological measures included assessments of baseline salivary cortisol and change in cortisol in response to the assessment session, and resting and suppression estimates of cardiac vagal tone. Cognitive self‐regulation was assessed with a peg‐tapping measure of inhibitory control and an item‐selection measure of cognitive set‐shifting ability. Results indicated that higher level of parent‐reported withdrawal motivation was associated with cortisol increase and that parent‐reported approach motivation tended to be associated with cortisol decrease across the assessment session. Higher level of parent‐reported withdrawal also was positively related to cognitive self‐regulation while parent‐reported approach was negatively related to cognitive self‐regulation. Person‐oriented analysis indicated that children characterized by both high level of approach and high level of withdrawal tended to exhibit lower resting vagal tone, higher initial cortisol, and minimal cortisol and vagal change. Overall, findings suggest that the parent‐report version of the BIS/BAS scales works well as an indicator of children's reactivity to appetitive and aversive motivational stimuli. Directions for future research and implications of findings for the longitudinal study of temperament and personality are discussed. © 2004 Wiley Periodicals, Inc. Dev Psychobiol 45: 113‐124, 2004.
Rewarding properties of social interactions in adolescent and adult male and female rats: Impact of social versus isolate housing of subjects and partners
Authors: Douglas Lewis A. , Varlinskaya Elena I. , Spear Linda P. 
Published: November 2004

AbstractSocial interactions have been shown to be rewarding for adolescent and adult rats; however, there has been little emphasis on comparing the strength of the rewarding value of social stimuli across ontogeny. Since age differences in social interactions may vary with sex or housing circumstances, the present study assessed social conditioned place preference (CPP) in adolescent and adult male and female Sprague‐Dawley rats housed either socially or in isolation and conditioned with either group‐housed or isolate‐housed partners. Isolated animals of both sexes and ages demonstrated social CPP, with the strongest preference emerging in adolescent males. Social CPP was not evident in group‐housed adults whereas group‐housed adolescents developed a preference for the compartment previously paired with similarly housed partners; however, when socially housed adolescents were conditioned with isolated partners, social CPP did not emerge. Age differences in social CPP may reflect age‐related neural alterations in brain systems implicated in regulation of social behavior. © 2004 Wiley Periodicals, Inc. Dev Psychobiol 45: 153‐162, 2004.
An audit of a British sample of death certificates in which anorexia nervosa is listed as a cause of death
Authors: Muir Anne , Palmer Robert L 
Published: November 2004

AbstractObjectiveAnorexia nervosa is associated with an increased mortality rate. National mortality statistics based on statutory death certification are potentially an important source of information. However, there are reasons to believe that these statistics may be subject to significant errors. An audit of the quality of information and diagnosis was conducted on death certificates in which anorexia nervosa was mentioned.MethodThe current study examined data from death certificates of people who died in England and Wales between 1993 and 1999.ResultsThere were 230 such deaths, but only 128—just over one half—were rated as likely to be deaths associated with true anorexia nervosa.DiscussionNational mortality statistics derived from death certificates are a flawed source of information on deaths from anorexia nervosa when taken at face value. There may be both underreporting and overreporting. Detailed examination may improve their usefulness by reducing the overerreporting. It seems likely that the association of deaths with anorexia nervosa is systematically underreported. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 36: 356–360, 2004.
A study on an improved absorbing boundary condition for a multimode waveguide analysis using the FDTD method
Authors: Kusama Yusuke , Ozaki Satoshi , Hashimoto Osamu 
Published: November 2004

AbstractWhen the FDTD method is applied to the analysis of a multimode waveguide, a problem is the treatment of the absorbing boundary corresponding to the matching at the termination. In the present study, the electromagnetic field in the cross section of the waveguide one cell inward from the termination is expressed as a linear combination of the eigenmodes of the waveguide. For the propagating mode, Mur's absorbing boundary condition is applied by means of the modal phase velocity, and the electromagnetic field at the termination is derived for each nonpropagating mode analytically by means of the modal attenuation constant. Finally, a linear combination is created at the termination to make a simple absorbing boundary. As a specific application, this procedure is applied to a waveguide with an H‐plane discontinuity for which the modal transmitted power is calculated, demonstrating the effectiveness of the procedure. Since the present technique is based on waveguide eigenmode expansion in the frequency domain, it can be used only for single‐frequency analysis. © 2004 Wiley Periodicals, Inc. Electron Comm Jpn Pt 2, 87(12): 1–9, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecjb.20110
Synthesis and Characterization of Lithium Complexes of 2‐(Diphenylphosphanylamino)pyridine and N,2‐Bis(diphenylphosphanyl)benzeneamine
Authors: Xavier Kochappilly O. , Smolensky Elena , Kapon Moshe , Aucott Stephen M. , Woollins J. Derek , Eisen Moris S. 
Published: November 2004

AbstractLithium complexes of 2‐(diphenylphosphinoamino)pyridine and N,2‐bis(diphenylphosphanyl)benzeneamine have been synthesized from the corresponding neutral compounds. In the former complex, the metal ion is coordinated to both nitrogen atoms, forming a constrained four‐membered ring, whereas the latter complex forms a five‐membered ring as the metal ion coordinates preferentially to the phosphorus atom. Coordination of the metal ion in both complexes is dictated primarily by soft−hard interactions and, subsequently, by the constrained geometry of the ring formed. Both lithium complexes and the corresponding neutral compounds have been characterized by single‐crystal X‐ray diffraction. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Solvothermal Syntheses and Structural Characterisation of Three Isostructural 3D Metal‐Malate Coordination Polymers: {[M(C4H4O5)(H2O)]·H2O}n (M = CoII, NiII, CoII/NiII)
Authors: Xie Feng‐Tong , Duan Li‐Mei , Xu Ji‐Qing , Ye Ling , Liu Ya‐Bing , Hu Xi‐Xue , Song Jiang‐Feng 
Published: November 2004

AbstractThree isostructural coordination polymers with the general formula {[M(C4H4O5)(H2O)]·H2O}n [M = CoII (1), NiII (2) and 1/3CoII + 2/3NiII (3), C4H4O5 = Hmal2−, malate dianion] have been designed and synthesised via solvothermal routes. In these compounds, the malate acts as the unique quinque‐dentate ligand with all five oxygen atoms participating in the coordination. The MII ions are interconnected via α‐ and β‐carboxyl groups from the malate ligands to generate zigzag chains and planes which are further linked together by the β‐carboxyl groups leading to the 3D open frameworks. Variable temperature magnetic susceptibility measurements indicate the occurrence of antiferromagnetic (1), ferromagnetic (2) and ferrimagnetic (3) interactions between the MII ions mediated by the skew‐skew carboxylate bridges. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
X‐ray and Solution Structures of the First Zn Funnel Complex Based on a Calix[6]aza‐cryptand
Authors: Darbost Ulrich , Zeng Xianshun , Rager Marie‐Noëlle , Giorgi Michel , Jabin Ivan , Reinaud Olivia 
Published: November 2004

AbstractFirst insights into the coordinative behavior of a calix[6]tren ligand are presented. Reaction with zinc perchlorate led to a dicationic complex with the metal ion strongly bound to the tren cap. It presents a unique coordination site accessible for a small coordinating molecule that is controlled by the calixarene cavity. Hence, X‐ray analysis and solution 1H NMR studies evidenced a five‐coordinate complex thanks to the coordination of a guest ligand, MeCN, included deep inside the calixarene cavity. Interestingly, the metal ion is bound in an asymmetrical environment in both the solid state and in solution. It is also particularly reluctant, and resistant, to anion binding. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Implicit and explicit measures of prejudice and stereotyping: do they assess the same underlying knowledge structure?
Authors: Dambrun Michaël , Guimond Serge 
Published: November 2004

AbstractDo implicit and explicit measures of ethnic attitudes assess the same underlying knowledge structure in long term memory? This study uses both a correlational and an experimental design (N = 133) in order to address this central question. In the first part, we suggest that self‐presentational strategies can partly explain why the relation between implicit and explicit measures is inconsistent in the existing literature. More specifically, we show that when there are strong norms against prejudice, implicit and explicit measures are significantly negatively related. In the second part, an experimental manipulation of relative gratification (RG), the opposite of relative deprivation, reveals that when the level of explicit prejudice increases (RG condition), a similar effect is also observed at the implicit level. Together, these results suggest that implicit and explicit measures assess similar knowledge structure. Copyright © 2004 John Wiley & Sons, Ltd.
History of Environmental and Molecular Mutagenesis
Authors: Hoffmann George R. 
Published: November 2004

AbstractEnvironmental and Molecular Mutagenesis, the journal of the Environmental Mutagen Society (EMS), marks its 25th anniversary in 2004. The journal, originally called Environmental Mutagenesis, was established in 1979 with Seymour Abrahamson as its first editor. The development of the journal is closely linked to the evolution of the fields of mutation research and genetic toxicology. This perspective traces the founding of the journal and discusses its editorial history, growth, content, style, administration, and relationship to the EMS. Environ. Mol. Mutagen., 2004. © 2004 Wiley‐Liss, Inc.
History of the science of mutagenesis from a personal perspective
Authors: Malling Heinrich V. 
Published: November 2004

AbstractA career in the study of mutagenesis spanning 50 years is a gift few scientists have been bestowed. My tenure in the field started in 1953, the year the structure of DNA became known (Watson and Crick [1953]: Nature 171:737). Before that time, it was suspected that DNA was the genetic material based on the research of Oswald T. Avery (Avery et al. [1944]: J Exp Med 79:137), but many scientists still believed that proteins or polysaccharides could be the genetic material. The present article describes a lifetime of personal experience in the field of chemical mutagenesis. The methods used to treat viruses with chemical mutagens were well developed in the 1950s. Here I review the early use of nitrous acid and hydroxylamine as mutagens in eukaryotes, the development of methods for the metabolic activation of mutagens by microsomal preparations, and the selection of a mutant tester set for the qualitative characterization of the mutagenic activity of chemicals. These studies provided critical background information that was used by Bruce Ames in the development of his Salmonella/microsome assay, widely known as the Ames test (Ames et al. [1973]: Proc Nat Acad Sci USA 70:2281–2285). This article also describes how a set of diagnostic chemical mutagens was selected and used to identify the molecular nature of gene mutations. Today, DNA sequencing has replaced the use of diagnostic mutagens, but studies of this kind formed the foundation of modern mutation research. They also helped set the stage for the organization of the Environmental Mutagen Society and the Environmental Mutagen Information Center, which are described. The article ends with the development of mammalian single‐cell mutation assays, the first system for studying in vivo mutagenesis using recoverable vectors in transgenic animals, other mutation assays in intact mammals, and my thoughts on the critically important area of germ cell mutagenesis. This narrative is not a complete autobiographical account, in that I have selected only those experiences that I feel are important for the history of the field and the edification of today's students. I hope I have shown that science not only is a valuable pursuit but can also be fun, stimulating, and satisfying. A good sense of humor and the knowledge that many discoveries come by serendipity are essential. Environ. Mol. Mutagen., 2004. Published 2004 Wiley‐Liss, Inc.
Modeling animal movements using stochastic differential equations
Authors: Preisler Haiganoush K. , Ager Alan A. , Johnson Bruce K. , Kie John G. 
Published: November 2004

AbstractWe describe the use of bivariate stochastic differential equations (SDE) for modeling movements of 216 radio‐collared female Rocky Mountain elk at the Starkey Experimental Forest and Range in northeastern Oregon. Spatially and temporally explicit vector fields were estimated using approximating difference equations and nonparametric regression techniques. Estimated vector fields of movement were mapped onto the project area at selected times of the day to examine spatial patterns of movement in relation to topography. Using the concept of a potential function, we were able to study the influence of roads and grassland foraging areas on elk movements. Doing so we identified broad spatial patterns of elk movements and showed the time dependent effects of habitat features within the habitat mosaic at Starkey. Our analyses quantify the cycles of movements in spring and summer in terms of attraction or repulsion to specific habitat features, and illustrate the magnitude, timing and direction of these movements. An extensive list of references is included. Published in 2004 by John Wiley & Sons, Ltd.
Bayesian density estimation using ranked set samples
Authors: Ghosh Kaushik , Tiwari Ram C. 
Published: November 2004

AbstractIn this article, we present a Bayesian approach for estimating the underlying density using a ranked set sample. We assume that the observations are generated from a Dirichlet process mixture model. Density (as well as moments) of future values generated from the process are estimated through Markov chain Monte Carlo simulations. This approach extends earlier work on density estimation based on a Dirichlet process prior from a simple random sample to a ranked set sample. We carry out a simulation study using a normal kernel to compare the effect of using a simple random sample versus a ranked set sample on the predictive density. We show that the Bayesian density estimate resulting from a ranked set sample has a smaller average mean squared error than that from a simple random sample. Additionally, the average Kullback–Leibler distance of the density estimate based on the ranked set sample is shown to be closer to zero than that based on the corresponding simple random sample. We illustrate our method by applying it to shrub data available in the literature. Copyright © 2004 John Wiley & Sons, Ltd.
Comparing the accuracy of density forecasts from competing models
Authors: Sarno Lucio , Valente Giorgio 
Published: November 2004

AbstractA rapidly growing literature emphasizes the importance of evaluating the forecast accuracy of empirical models on the basis of density (as opposed to point) forecasting performance. We propose a test statistic for the null hypothesis that two competing models have equal density forecast accuracy. Monte Carlo simulations suggest that the test, which has a known limiting distribution, displays satisfactory size and power properties. The use of the test is illustrated with an application to exchange rate forecasting. Copyright © 2004 John Wiley & Sons, Ltd.
Microcell‐mediated transfer of chromosome 4 into HeLa cells suppresses telomerase activity
Authors: Backsch Claudia , Wagenbach Nikola , Nonn Marion , Leistritz Sabine , Stanbridge Eric , Schneider Achim , Dürst Matthias 
Published: November 2004

AbstractTelomerase activity can be detected in most human cancers and immortal cell lines. In contrast, the lack of telomerase activity in normal diploid fibroblasts has been correlated with progressive reduction of telomere lengths to critically short sizes followed by the cessation of cell division and the onset of senescence. Several investigators have provided evidence for the localization of a telomerase suppressor gene on chromosome 3. The aim of our study was to determine whether other chromosomes are involved in telomerase repression. Beside human chromosome 3 (serving as positive control), chromosomes 4, 6, and 11 were introduced into HeLa cells via microcell‐mediated chromosome transfer. Telomerase activity from different hybrid cell lysates was determined at an early time point after fusion using a Telomerase ELISA kit. Strong repression of telomerase activity was only found in a subset of HeLa hybrids in which chromosome 3 or chromosome 4 had been introduced. Telomerase suppression induced by chromosome 3 or 4 transfer was paralleled by a high frequency (30% or 43%, respectively) of a senescent‐like phenotype. Chromosomes 6 and 11, the functional loss of which is also implicated in cervical cancer, had no effect. These results indicate that normal human chromosomes 3 and 4 carry a gene or genes that suppress telomerase activity and induce cellular senescence in HeLa cells.©2001 Wiley‐Liss, Inc.
Characterization of oncogene dysregulation in multiple myeloma by combined FISH and DNA microarray analyses
Authors: Fabris Sonia , Agnelli Luca , Mattioli Michela , Baldini Luca , Ronchetti Domenica , Morabito Fortunato , Verdelli Donata , Nobili Lucia , Intini Daniela , Callea Vincenzo , Stelitano Caterina , Lombardi Luigia , Neri Antonino 
Published: November 2004

AbstractChromosomal translocations involving the immunoglobulin heavy chain (IGH) locus and various partner loci frequently are associated with multiple myeloma (MM). We investigated the expression profiles of the FGFR3/MMSET, CCND1, CCND3, MAF, and MAFB genes, which are involved in t(4;14)(p16.3;q32), t(11;14)(q13;q32), t(6;14)(p21;q32), t(14;16)(q32;q23), and t(14;20)(q32;q12), respectively, in purified plasma cell populations from 39 MMs and six plasma cell leukemias (PCL) by DNA microarray analysis and compared the results with the presence of translocations as assessed by dual‐color FISH or RT‐PCR. A t(4;14) was found in 6 MMs, t(11;14) in 9 MMs and 1 PCL, t(6;14) in 1 MM, t(14;16) in 2 MMs and 1 PCL, and t(14;20) in 1 PCL. In all cases, the translocations were associated with the spiked expression of target genes. Furthermore, gene expression profiling enabled the identification of putative translocations causing dysregulation of CCND1 (1 MM and 1 PCL) and MAFB (1 MM and 1 PCL) without any apparent involvement of immunoglobulin loci. Notably, all of the translocations were mutually exclusive. Markedly increased MMSET expression was found in 1 MM showing associated FGFR3 and MMSET signals on an unidentified chromosome. Our data suggest the importance of using combined molecular cytogenetic and gene expression approaches to detect genetic aberrations in MM. © 2004 Wiley‐Liss, Inc.
Translocation t(X;11)(q13;q23) in B‐cell chronic lymphocytic leukemia disrupts two novel genes
Authors: Kalla Claudia , Nentwich Hagen , Schlotter Magdalena , Mertens Daniel , Wildenberger Kathrin , Döhner Hartmut , Stilgenbauer Stephan , Lichter Peter 
Published: November 2004

AbstractDeletion of chromosome region 11q22–q23 defines a subgroup of patients with B‐cell chronic lymphocytic leukemia (B‐CLL) characterized by poor survival. Although the tumor‐suppressor gene ATM in the consensus deletion region was found to be biallelically inactivated in about one third of B‐CLL cases, in the majority of those who have this deletion, inactivation of the remaining ATM allele was not observed. To identify a second disease‐associated gene, we investigated two B‐CLL cases with translocation breakpoints in the critical 11q23 deletion region. In one case, a t(X;11)(q13;q23) was cloned and two novel genes were isolated. The breakpoint on 11q23 affected the ARHGAP20 gene, which encodes a protein predicted to be involved in the regulation of Rho family GTPases. The breakpoint on Xq13 occurred in BRWD3, which codes for a putative novel transcription factor. The rearrangement of ARHGAP20 and BRWD3 did not result in fusion transcripts, but it disrupted both genes. Mutation analysis of 28 B‐CLL samples with monoallelic deletions and two B‐CLL samples with 11q23 translocations detected no deleterious mutation in the remaining copy of ARHGAP20. Quantitative expression analysis in 22 B‐CLLs revealed significant up‐regulation of ARHGAP20 in CLL B cells, whereas BRWD3 was slightly down‐regulated. Thus, deregulation of ARHGAP20 by altered gene expression or by gene disruption (but not point mutation) might be a general molecular mechanism of B‐CLL leukemogenesis. © 2004 Wiley‐Liss, Inc.