bluuebunny/crossref_metadata_2025_split huggingface dataset:
PFOA and PFOS induces mineralization of soil organic carbon by accelerating the consumption of dissolved organic carbon
Authors: Li Yulong , Lv Bowei , Chen Zhendong , Xue Jianming , Wu Li , He Xiaoman , Yang Lie 
Published: February 2024

AbstractThe wide spread of Perfluoroalkyl substances (e.g., PFOA and PFOS) in soil can alter native soil geochemical properties and microbial communities through various approaches. Nonetheless, it is unclear that how PFOA and PFOS in soil affect the mineralization of soil organic carbon (SOC). A laboratory-scale culture experiment (180 d) was performed to explore the contribution of PFOA and PFOS to SOC dynamics and soil geochemical processes. Results showed that positive priming effect (PE) occurred in the short term (i.e., 30 days after PFOA and PFOS addition) and subsequently shifted to a slightly negative PE (i.e., 90 days) and remained in a significant negative PE thereafter (i.e., > 180 days). The PEs caused by PFOA and PFOS both accelerated the consumption of dissolved organic carbon (DOC), resulting in a significant increase in SOC mineralization (10.45%–127.36%) under the short-term incubation (30 d). As for long-term exposure (> 90 d), the organic carbon mineralization rate was significantly reduced (58.30%–65.24%) due to the excessive DOC consumption in the initial stage. High throughput analysis indicated that both PFOA and PFOS changed soil bacterial and fungal community structures, altered the relevant metabolic pathways and resulted in the enrichment of specific taxa.
Graphical Abstract
Three-dimentional reconstruction of underwater side-scan sonar images based on shape-from-shading and monocular depth fusion
Authors: Ju Yakun , Zhou Jingchun , Zhou Shitong , Xie Hao , Zhang Cong , Xiao Jun , Yang Cuixin , Sun Jianyuan 
Published: February 2024

AbstractModern marine research requires high-precision three-dimensional (3D) underwater data. Underwater environments experience severe visible light attenuation, which leads to inferior imaging compared with air. In contrast, sound waves are less affected underwater; hence side-scan sonar is used for underwater 3D reconstruction. Typically, the shape-from-shading algorithm (SfS) is widely used to reconstruct surface normal or heights from side-scan sonar images. However, this approach has challenges because of global information loss and noise. To address these issues, this study introduces a surface-normal fusion method. Specifically, we propose a frequency separation SfS algorithm using a discrete cosine transform, which provides a surface-normal map with less noise. We then fuse the surface-normal map with a novel depth estimation network to achieve high-precision 3D reconstruction of underwater side-scan sonar images. We conducted experiments on synthetic, NYU-depth-v2, and real side-scan sonar datasets to demonstrate the effectiveness of the proposed method.
Development and reform of marine spatial planning in China under the new territorial spatial planning system
Authors: Gao Jinzhu , An Taitian , Zhang Kuncheng , Zhao Rui 
Published: February 2024

AbstractOver the last two decades, countries worldwide have become increasingly aware of the potential of marine space, which has led to a significant development in marine spatial planning (MSP) and the proliferation of studies and practical exploration of MSP issues. In China, MSP is undergoing a new series of reforms. Despite discussions in the academic community on the methods and mechanisms of MSP, issues related to planning, system designs, and implementation priorities for the next stage of MSP in China remain unresolved. This study describes the multiplan integration characterization of MSP in China. It intends to address these issues by presenting a potential MSP system and defining the specific contents and tools that need to be applied to coastal spatial planning (CSP). CSP will be at the core of MSP in China in the future.
Comparison of Forecasting Biases Over New York State Mesonet: A Wet Summer Versus a Dry Summer
Authors: Min Lanxi , Min Qilong , Wang Chiming 
Published: February 2024

AbstractExtreme weather events are occurring with increasing frequent due to the climate change. This increasing frequency may introduce more uncertainty in weather forecasting model performance, particularly when considering the intricate relationship of the land surface and atmosphere coupling system. In this study, we utilize data from the sophisticated New York State Mesonet to evaluate the performance of a forecasting system based on WRF Version 4 model, drawing insights from both dry and wet summers. Additionally, the model's performance is assessed on two land surface types: forest and farmland, to provide a comprehensive evaluation of impact of land surface heterogeneity. The surface meteorology, fluxes, and cloud development are assessed. The coupling between surface and atmosphere is diagnosed using a mixing diagram which serves to represent surface thermodynamic properties. The results reveal a systematic increase in warm season dry and warm biases, especially for forested sites during a drought year. The model exhibits heightened sensitivity to drought conditions, resulting in a substantial underestimation of latent heat fluxes during such period. During days with boundary layer clouds, the mixing diagram shows a notably slower growth of moist static energy in the model compared to observation. It is possible that these biases partly attribute to the underestimation of cloud optical depth due to not enough energy for the cloud development.
Windows into the past: recent scientific techniques in dental analysis
Authors: Forshaw Roger 
Published: February 2024

AbstractTeeth are the hardest and most chemically stable tissues in the body, are well-preserved in archaeological remains and, being resistant to decomposition in the soil, survive long after their supporting structures have deteriorated. It has long been recognised that visual and radiographic examination of teeth can provide considerable information relating to the lifestyle of an individual. This paper examines the latest scientific approaches that have become available to investigate recent and ancient teeth. These techniques include DNA analysis, which can be used to determine the sex of an individual, indicate familial relationships, study population movements, provide phylogenetic information and identify the presence of disease pathogens. A stable isotopic approach can shed light on aspects of diet and mobility and even research climate change. Proteomic analysis of ancient dental calculus can reveal specific information about individual diets. Synchrotron microcomputed tomography is a non-invasive technique which can be used to visualise physiological impactful events, such as parturition, menopause and diseases in cementum microstructure - these being displayed as aberrant growth lines.
The small molecule raptinal can simultaneously induce apoptosis and inhibit PANX1 activity
Authors: Santavanond Jascinta P. , Chiu Yu-Hsin , Tixeira Rochelle , Liu Zonghan , Yap Jeremy K. Y. , Chen Kaiwen W. , Li Chen-Lu , Lu Yi-Ru , Roncero-Carol Joan , Hoijman Esteban , Rutter Stephanie F. , Shi Bo , Ryan Gemma F. , Hodge Amy L. , Caruso Sarah , Baxter Amy A. , Ozkocak Dilara C. , Johnson Chad , Day Zoe I. , Mayfosh Alyce J. , Hulett Mark D. , Phan Thanh K. , Atkin-Smith Georgia K. , Poon Ivan K. H. 
Published: February 2024

AbstractDiscovery of new small molecules that can activate distinct programmed cell death pathway is of significant interest as a research tool and for the development of novel therapeutics for pathological conditions such as cancer and infectious diseases. The small molecule raptinal was discovered as a pro-apoptotic compound that can rapidly trigger apoptosis by promoting the release of cytochrome c from the mitochondria and subsequently activating the intrinsic apoptotic pathway. As raptinal is very effective at inducing apoptosis in a variety of different cell types in vitro and in vivo, it has been used in many studies investigating cell death as well as the clearance of dying cells. While examining raptinal as an apoptosis inducer, we unexpectedly identified that in addition to its pro-apoptotic activities, raptinal can also inhibit the activity of caspase-activated Pannexin 1 (PANX1), a ubiquitously expressed transmembrane channel that regulates many cell death-associated processes. By implementing numerous biochemical, cell biological and electrophysiological approaches, we discovered that raptinal can simultaneously induce apoptosis and inhibit PANX1 activity. Surprisingly, raptinal was found to inhibit cleavage-activated PANX1 via a mechanism distinct to other well-described PANX1 inhibitors such as carbenoxolone and trovafloxacin. Furthermore, raptinal also interfered with PANX1-regulated apoptotic processes including the release of the ‘find-me’ signal ATP, the formation of apoptotic cell-derived extracellular vesicles, as well as NLRP3 inflammasome activation. Taken together, these data identify raptinal as the first compound that can simultaneously induce apoptosis and inhibit PANX1 channels. This has broad implications for the use of raptinal in cell death studies as well as in the development new PANX1 inhibitors.
Conserved mechanisms of self-renewal and pluripotency in mouse and human ESCs regulated by simulated microgravity using a 3D clinostat
Authors: Ye Ying , Xie Wenyan , Ma Zhaoru , Wang Xuepeng , Wen Yi , Li Xuemei , Qi Hongqian , Wu Hao , An Jinnan , Jiang Yan , Lu Xinyi , Chen Guokai , Hu Shijun , Blaber Elizabeth A. , Chen Xi , Chang Lei , Zhang Wensheng 
Published: February 2024

AbstractEmbryonic stem cells (ESCs) exhibit unique attributes of boundless self-renewal and pluripotency, making them invaluable for fundamental investigations and clinical endeavors. Previous examinations of microgravity effects on ESC self-renewal and differentiation have predominantly maintained a descriptive nature, constrained by limited experimental opportunities and techniques. In this investigation, we present compelling evidence derived from murine and human ESCs, demonstrating that simulated microgravity (SMG)-induced stress significantly impacts self-renewal and pluripotency through a previously unidentified conserved mechanism. Specifically, SMG induces the upregulation of heat shock protein genes, subsequently enhancing the expression of core pluripotency factors and activating the Wnt and/or LIF/STAT3 signaling pathways, thereby fostering ESC self-renewal. Notably, heightened Wnt pathway activity, facilitated by Tbx3 upregulation, prompts mesoendodermal differentiation in both murine and human ESCs under SMG conditions. Recognizing potential disparities between terrestrial SMG simulations and authentic microgravity, forthcoming space flight experiments are imperative to validate the impact of reduced gravity on ESC self-renewal and differentiation mechanisms.
Effects of vasodilators on beat-to-beat and every fifteen minutes blood pressure variability induced by noradrenaline infusion in rats
Authors: Jiang Danfeng , Matsuzaki Minami , Ida Takanori , Kitamura Kazuo , Kato Johji 
Published: February 2024

AbstractIncreased blood pressure variability (BPV) was shown to be associated with cardiovascular morbidities and/or mortalities. There are various types of BPV depending on time intervals of BP measurements, ranging from beat-to-beat to visit-to-visit or year-to-year. We previously found that continuous infusion of noradrenaline (NA) for 14 days increased short-term BPV every 15 min in rats. The aims of this study were to examine (1) whether NA infusion increases very short-term beat-to-beat BPV, (2) the effects of azelnidipine and hydralazine on NA-induced BPV, and (3) whether baroreceptor reflex sensitivity (BRS) is affected by NA or NA plus those vasodilators. Nine-week-old Wistar rats infused subcutaneously with 30 μg/h NA were orally treated with or without 9.7 mg/day azelnidipine or 5.9 mg/day hydralazine over 14 days. BP levels were continuously monitored via abdominal aortic catheter with a telemetry system in an unrestrained condition. Standard deviations (SDs) were used to evaluate beat-to-beat BPV and BPV every 15 min which was obtained by averaging BP levels for 10-s segment at each time point. BRS was determined by a sequence analysis. Continuous NA infusion over 14 days increased average BP, beat-to-beat BPV, and BPV every 15 min, lowering BRS. Comparing the two vasodilators, hydralazine reduced BP elevation by NA; meanwhile, azelnidipine alleviated BPV augmentation, preserving BRS, despite a smaller BP reduction. Thus, NA infusion increased both very short- and short-term BPV concomitantly with impaired BRS, while azelnidipine had an inhibitory effect, possibly independent of BP-lowering, on those types of BPV and impairment of BRS.
Mediating trade-off between activity and selectivity in alkynes semi-hydrogenation via a hydrophilic polar layer
Authors: Xiong Jinqi , Mao Shanjun , Luo Qian , Ning Honghui , Lu Bing , Liu Yanling , Wang Yong 
Published: February 2024

AbstractAs a crucial industrial process for the production of bulk and fine chemicals, semi-hydrogenation of alkynes faces the trade-off between activity and selectivity due to undesirable over-hydrogenation. By breaking the energy linear scaling relationships, we report an efficient additive-free WO3-based single-atom Pd catalytic system with a vertical size effect of hydrogen spillover. Hydrogen spillover induced hydrophilic polar layer (HPL) with limited thickness on WO3-based support exhibits unconventional size effect to Pd site, in which over-hydrogenation is greatly suppressed on Pd1 site due to the polar repulsive interaction between HPL and nonpolar C=C bonds, whereas this is invalid for Pd nanoparticles with higher altitudes. By further enhancing the HPL through Mo doping, activated Pd1/MoWO3 achieves recorded performance of 98.4% selectivity and 10200 h−1 activity for semi-hydrogenation of 2-methyl-3-butyn-2-ol, 26-fold increase in activity of Lindlar catalyst. This observed vertical size effect of hydrogen spillover offers broad potential in catalytic performance regulation.
Evaluating vector competence for Yellow fever in the Caribbean
Authors: Gabiane Gaelle , Bohers Chloé , Mousson Laurence , Obadia Thomas , Dinglasan Rhoel R. , Vazeille Marie , Dauga Catherine , Viglietta Marine , Yébakima André , Vega-Rúa Anubis , Gutiérrez Bugallo Gladys , Gélvez Ramírez Rosa Margarita , Sonor Fabrice , Etienne Manuel , Duclovel-Pame Nathalie , Blateau Alain , Smith-Ravin Juliette , De Lamballerie Xavier , Failloux Anna-Bella 
Published: February 2024

AbstractThe mosquito-borne disease, Yellow fever (YF), has been largely controlled via mass delivery of an effective vaccine and mosquito control interventions. However, there are warning signs that YF is re-emerging in both Sub-Saharan Africa and South America. Imported from Africa in slave ships, YF was responsible for devastating outbreaks in the Caribbean. In Martinique, the last YF outbreak was reported in 1908 and the mosquito Aedes aegypti was incriminated as the main vector. We evaluated the vector competence of fifteen Ae. aegypti populations for five YFV genotypes (Bolivia, Ghana, Nigeria, Sudan, and Uganda). Here we show that mosquito populations from the Caribbean and the Americas were able to transmit the five YFV genotypes, with YFV strains for Uganda and Bolivia having higher transmission success. We also observed that Ae. aegypti populations from Martinique were more susceptible to YFV infection than other populations from neighboring Caribbean islands, as well as North and South America. Our vector competence data suggest that the threat of re-emergence of YF in Martinique and the subsequent spread to Caribbean nations and beyond is plausible.
Convergent evolutionary patterns of heterostyly across angiosperms support the pollination-precision hypothesis
Authors: Simón-Porcar Violeta , Escudero Marcial , Santos-Gally Rocío , Sauquet Hervé , Schönenberger Jürg , Johnson Steven D. , Arroyo Juan 
Published: February 2024

AbstractSince the insights by Charles Darwin, heterostyly, a floral polymorphism with morphs bearing stigmas and anthers at reciprocal heights, has become a model system for the study of natural selection. Based on his archetypal heterostylous flower, including regular symmetry, few stamens and a tube, Darwin hypothesised that heterostyly evolved to promote outcrossing through efficient pollen transfer between morphs involving different areas of a pollinator’s body, thus proposing his seminal pollination-precision hypothesis. Here we update the number of heterostylous and other style-length polymorphic taxa to 247 genera belonging to 34 families, notably expanding known cases by 20%. Using phylogenetic and comparative analyses across the angiosperms, we show numerous independent origins of style-length polymorphism associated with actinomorphic, tubular flowers with a low number of sex organs, stamens fused to the corolla, and pollination by long-tongued insects. These associations provide support for the Darwinian pollination-precision hypothesis as a basis for convergent evolution of heterostyly across angiosperms.
Generating active metal/oxide reverse interfaces through coordinated migration of single atoms
Authors: Zhang Lina , Wan Shaolong , Du Congcong , Wan Qiang , Pham Hien , Zhao Jiafei , Ding Xingyu , Wei Diye , Zhao Wei , Li Jiwei , Zheng Yanping , Xie Hui , Zhang Hua , Chen Mingshu , Zhang Kelvin H. L. , Wang Shuai , Lin Jingdong , Huang Jianyu , Lin Sen , Wang Yong , Datye Abhaya K. , Wang Ye , Xiong Haifeng 
Published: February 2024

AbstractIdentification of active sites in catalytic materials is important and helps establish approaches to the precise design of catalysts for achieving high reactivity. Generally, active sites of conventional heterogeneous catalysts can be single atom, nanoparticle or a metal/oxide interface. Herein, we report that metal/oxide reverse interfaces can also be active sites which are created from the coordinated migration of metal and oxide atoms. As an example, a Pd1/CeO2 single-atom catalyst prepared via atom trapping, which is otherwise inactive at 30 °C, is able to completely oxidize formaldehyde after steam treatment. The enhanced reactivity is due to the formation of a Ce2O3-Pd nanoparticle domain interface, which is generated by the migration of both Ce and Pd atoms on the atom-trapped Pd1/CeO2 catalyst during steam treatment. We show that the generation of metal oxide-metal interfaces can be achieved in other heterogeneous catalysts due to the coordinated mobility of metal and oxide atoms, demonstrating the formation of a new active interface when using metal single-atom material as catalyst precursor.
Synergistic-potential engineering enables high-efficiency graphene photodetectors for near- to mid-infrared light
Authors: Jiang Hao , Fu Jintao , Wei Jingxuan , Li Shaojuan , Nie Changbin , Sun Feiying , Wu Qing Yang Steve , Liu Mingxiu , Dong Zhaogang , Wei Xingzhan , Gao Weibo , Qiu Cheng-Wei 
Published: February 2024

AbstractHigh quantum efficiency and wide-band detection capability are the major thrusts of infrared sensing technology. However, bulk materials with high efficiency have consistently encountered challenges in integration and operational complexity. Meanwhile, two-dimensional (2D) semimetal materials with unique zero-bandgap structures are constrained by the bottleneck of intrinsic quantum efficiency. Here, we report a near-mid infrared ultra-miniaturized graphene photodetector with configurable 2D potential well. The 2D potential well constructed by dielectric structures can spatially (laterally and vertically) produce a strong trapping force on the photogenerated carriers in graphene and inhibit their recombination, thereby improving the external quantum efficiency (EQE) and photogain of the device with wavelength-immunity, which enable a high responsivity of 0.2 A/W–38 A/W across a broad infrared detection band from 1.55 to 11 µm. Thereafter, a room-temperature detectivity approaching 1 × 109 cm Hz1/2 W−1 is obtained under blackbody radiation. Furthermore, a synergistic effect of electric and light field in the 2D potential well enables high-efficiency polarization-sensitive detection at tunable wavelengths. Our strategy opens up alternative possibilities for easy fabrication, high-performance and multifunctional infrared photodetectors.
Regulation of TRI5 expression and deoxynivalenol biosynthesis by a long non-coding RNA in Fusarium graminearum
Authors: Huang Panpan , Yu Xiao , Liu Huiquan , Ding Mingyu , Wang Zeyi , Xu Jin-Rong , Jiang Cong 
Published: February 2024

AbstractDeoxynivalenol (DON) is the most frequently detected mycotoxin in cereal grains and processed food or feed. Two transcription factors, Tri6 and Tri10, are essential for DON biosynthesis in Fusarium graminearum. In this study we conduct stranded RNA-seq analysis with tri6 and tri10 mutants and show that Tri10 acts as a master regulator controlling the expression of sense and antisense transcripts of TRI6 and over 450 genes with diverse functions. TRI6 is more specific for regulating TRI genes although it negatively regulates TRI10. Two other TRI genes, including TRI5 that encodes a key enzyme for DON biosynthesis, also have antisense transcripts. Both Tri6 and Tri10 are essential for TRI5 expression and for suppression of antisense-TRI5. Furthermore, we identify a long non-coding RNA (named RNA5P) that is transcribed from the TRI5 promoter region and is also regulated by Tri6 and Tri10. Deletion of RNA5P by replacing the promoter region of TRI5 with that of TRI12 increases TRI5 expression and DON biosynthesis, indicating that RNA5P suppresses TRI5 expression. However, ectopic constitutive overexpression of RNA5P has no effect on DON biosynthesis and TRI5 expression. Nevertheless, elevated expression of RNA5P in situ reduces TRI5 expression and DON production. Our results indicate that TRI10 and TRI6 regulate each other’s expression, and both are important for suppressing the expression of RNA5P, a long non-coding RNA with cis-acting inhibitory effects on TRI5 expression and DON biosynthesis in F. graminearum.