bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of Patient-Facing Mobile Apps to Support Physiotherapy Care: Systematic Review
Authors: Merolli Mark , Francis Jill J , Vallance Patrick , Bennell Kim L , Malliaras Peter , Hinman Rana S 
Published: January 2024

Background
Mobile health interventions delivered through mobile apps are increasingly used in physiotherapy care. This may be because of the potential of apps to facilitate changes in behavior, which is central to the aims of care delivered by physiotherapists. A benefit of using apps is their ability to incorporate behavior change techniques (BCTs) that can optimize the effectiveness of physiotherapeutic interventions. Research continues to suggest that despite their importance, behavior change strategies are often missing in patient management. Evaluating mobile apps that physiotherapists can use to drive behavior change may inform clinical practice and potentially improve patient outcomes. Examining the quality of apps and exploring their key features that can support behavior change and physiotherapy care are important aspects of such an evaluation.

Objective
The primary aim of this study was to describe the range of mobile apps in app stores that are intended for use by patients to support physiotherapy care. The secondary aims were to assess app quality, BCTs, and their behavior change potential.

Methods
A systematic review of mobile apps in app stores was undertaken. The Apple App Store and Google Play were searched using a 2-step search strategy, using terms relevant to the physiotherapy discipline. Strict inclusion and exclusion criteria were applied: apps had to be intended for use by patients and be self-contained (or stand-alone) without the requirement to be used in conjunction with a partner wearable device or another plugin. Included apps were coded for BCTs using the Behavior Change Technique Taxonomy version 1. App quality was assessed using the Mobile App Rating Scale, and the App Behavior Change Scale was used to assess the app’s potential to change behavior.

Results
In total, 1240 apps were screened, and 35 were included. Of these 35 apps, 22 (63%) were available on both the Apple App Store and Google Play platforms. In total, 24 (69%) were general in their focus (eg, not condition-specific), with the remaining 11 (31%) being more specific (eg, knee rehabilitation and pelvic floor training). The mean app quality score (Mobile App Rating Scale) was 3.7 (SD 0.4) of 5 (range 2.8-4.5). The mean number of BCTs identified per app was 8.5 (SD 3.6). BCTs most frequently included in the apps were instruction on how to perform a behavior (n=32), action planning (n=30), and self-monitoring of behavior (n=28). The mean behavior change potential score (App Behavior Change Scale) was 8.5 (SD 3.1) of 21 (range 3-15).

Conclusions
Mobile apps available to support patient care received from a physiotherapist are of variable quality. Although they contain some BCTs, the potential for behavior change varied widely across apps.

International Registered Report Identifier (IRRID)
RR2-10.2196/29047
Innovation in Audit and Assurance: A Global Study of Disruptive Technologies
Authors: Seidenstein Tom , Marten Kai-Uwe , Donaldson Giovanni , Föhr Tassilo L. , Reichelt Valentin , Jakoby Lena B. 
Published: January 2024

ABSTRACT
The study at hand develops the Audit and Assurance Value Chain as a structured framework with four categories: accessing information and data, verifying information, protecting information, and assessing internal controls. After development of the Audit and Assurance Value Chain, it was utilized to categorize emerging technologies derived out of investigations of more than 100 technology innovator companies and interviews with 23 organizations comprising audit and assurance practitioners, regulators, associations, and national standard-setters. The study is based on global data coverage to identify emerging technologies that have not been connected to audit and assurance services before, bringing new insights to the field. Additionally, it emphasizes the importance of the International Auditing and Assurance Standards Board convening power and influence in promoting the adoption of emerging technologies.
JEL Classification: M40; M41; M42; O30; O32; O33.
SISTEM INFORMASI ADMINISTRASI PENGOLAHAN LIMBAH PADA PT. ELANG HIJAU BENGKULU SEJAHTERA (EHBS)
Authors: Marizky Syafrizza Aulia , Ramadani Niska , Oktoeberza KZ Widhia 
Published: January 2024

PT. Elang Hijau Bengkulu Sejahtera adalah Perusahaan yang bergerak dibidang pengolaan limbah berbahaya dan beracun daerah, tugas dan fungsi Perusahaan adalah sebagai Central Temporary Storage Medical Waste, Chemical Waste, dan Industrial Hazardus Waste yang memiliki Kerjasama dengan Multi Vendor Transporter B3 nasional. Pendataan mengenai limbah yang telah diangkut Kembali di Gudang masih menggunakan pendataan manual, hal ini dinilai kurang efektif dan membutuhkan waktu yang lama, untuk mengatasi permasalahan tersebut dibutuhkan suatu sistem informasi yang dapat menjalankan proses manajemen pendataan dengan lebih efektif. Sistem Informasi Administrasi Pengolaan Limbah ini merupakan aplikasi yang berbasis website yang dibangun untuk proses pendataan data limbah medis dan limbah nonmedis. Sistem informasi ini dirancang dengan menggunakan metodologi penelitian yaitu metode pengumpulan data dan pengembangan sistem dengan menggunakan metode waterfall. Sistem dibuat dengan menggunakan Bahasa pemrograman PHP, database MySQL, dan Laravel 8.
FISIOTERAPI PADA POST PARTUM DENGAN PILATES EXERCISE UNTUK MENINGKATKAN FLEKSIBILITAS LUMBAL
Authors: Hidayati Zein Renni , Muawanah Siti , Ismaningsih Ismaningsih 
Published: January 2024

Latar belakang : Post Partum merupakan periode waktu atau masa dimana organ-organ reproduksi kembali kepada keadaan tidak hamil membutuhkan waktu sekitar 6 minggu. Fleksibilitas dipengaruhi oleh elastisitasnya sendi-sendi dan juga otot-otot. Salah satu upaya untuk meningkatkan fleksibilitas lumbal pada kasus post partum adalah dengan pemberian intervensi pilates exercise. Tujuan dari pemberian intervensi ini yaitu meningkatkan fleksibilitas lumbal, menjaga fleksibilitas otot, dan memperbaiki postur. Metode : Penelitian ini adalah penelitian Pra Eksperimen dengan One group pre-test & post-test design. Populasi sampel adalah post partum dengan gangguan fleksibilitas lumbal UPT Puskesmas Kelurahan Enok. Pengambilan data pasien dengan menggunakan midline pre-test dan post-test. Selama masa penelitian jumlah sampel sebanyak 22 responden yang diambil menggunakan teknik total sampling yaitu seluruh penderita. Hasil : Hasil penelitian menunjukkan fleksibilitas sebelum & sesudah pemberian intervensi menunjukkan ada perubahan yang signifikan dari nilai p=0,000 dengan tingkat kepercayaan 95%. Berdasarkan Uji Paired Sampel T Test dengan nilai p= 0,000 < (0,05) telah memperlihatkan bahwa terdapat pengaruh pilates exercise terhadap perubahan fleksibilitas lumbal pada post partum. Kesimpulan : Disimpulkan bahwa fleksibilitas sebelum & sesudah pemberian pillates exercise memperlihatkan ada peningkatan fleksibilitas setelah diberikan pilates exercise dengan frekuensi latihan 3 kali selama 3 minggu.
Effect of an aqueous extract of black walnut (Juglans nigra) on isolated equine digital vessels
Authors: Galey F. D. , Beasley V. R. , Schaeffer D. , Davis L. E. 
Published: January 2024

SUMMARY
An aqueous extract was made from black walnut (Juglans nigra) heartwood obtained in the fall of the year. Ten hours after nasogastric administration of 5 L of the extract, a 550-kg, 13-yr-old Quarter Horse gelding experienced Obel grade-3 laminitis.
The effect of aqueous extract of black walnut on vascular contractility was then tested, using isolated equine digital arteries and veins. The vessels were maintained in Krebs bicarbonate buffer with 95% oxygen at 37 C. The extract did not induce a direct contractile effect. It did, however, reversibly enhance the vasoconstriction induced in the isolated vessels by administration of epinephrine potentiated with hydrocortisone.
In contrast, aqueous extracts made, using the same techniques, from the shavings of eastern white pine (Pinus strobus), eastern red cedar (Juniperus virginiana), and pin oak (Quercus palustrus) had no effect on epinephrine-induced digital vessel contractions.
Effect of muramyl dipeptide on immunogenicity of Corynebacterium pseudotuberculosis whole-cell vaccines in mice and lambs
Authors: Brogden Kim A. , Chedid Louis , Cutlip Randall C. , Lehmkuhl Howard D. , Sacks Jerome 
Published: January 2024

SUMMARY
Colostrum-deprived lambs and CF1 mice were vaccinated with water-in-oil emulsion vaccines containing nonviable whole cells (wc) of Corynebacterium pseudotuberculosis with and without muramyl dipeptide (mdp). Efficacy of vaccines was determined from the survival of mice and lesions in lambs after IV injection of 104 colony-forming units of C pseudotuberculosis. In mice, protection was related to the concentration of wc in the vaccine. At 50, 100, or 150 μg of wc, protection was good (78.8%). At 10 or 25 μg of wc, protection was considerably less (54.7%). At high wc concentrations, protection could only be moderately increased to 82.3% with high (50 and 100 μg) concentrations of mdp or increased to 90% protection with low (5 and 10 μg) concentrations of mdp. At low wc concentrations, protection significantly decreased to 32% (P < 0.025) with high concentrations of mdp, but significantly increased to 72.5% (P < 0.025) with low concen-trations of mdp. Therefore, the amount of protection with lower concentrations of wc and mdp was comparable with the amount of protection with higher concentrations of wc without mdp.
In lambs, high prechallenge antibody titers (geometric mean titers from 5.1 to 5.4 by day 35) were observed after vaccination with wc. Protection and vaccination site abscesses in lambs were related to the concentration of wc and mdp. Pulmonary or vaccination site abscesses were not observed in 4 of 4 lambs vaccinated with 1 mg of wc + 50 μg of mdp.
Effects of exocrine pancreatic insufficiency and replacement therapy on the bacterial flora of the duodenum in dogs
Authors: Simpson Kenneth W. , Batt Roger M. , Jones Dorothy , Morton David B. 
Published: January 2024

SUMMARY
The influence of pancreatic secretions on the bacterial flora of the small intestine in 6 dogs was investigated by determining effects of exocrine pancreatic insufficiency on numbers and types of bacteria in duodenal juice, and by examining the subsequent response to dietary supplementation with bovine pancreatic extract. Exocrine pancreatic insufficiency was induced by ligation of pancreatic ducts and was confirmed by indirect assessment of exocrine pancreatic function. Duct ligation was followed by large increases (P < 0.01) in total numbers of bacteria, reflecting increased numbers particularly of Lactobacillus spp and Streptococcus spp, in 3 dogs accompanied by obligate anaerobes. Total numbers of aerobes and anaerobes decreased markedly (P < 0.05) after supplementation with bovine pancreatic extract to values that were not significantly different from those determined before duct ligation. Exocrine pancreatic insufficiency therefore resulted in small intestinal bacterial overgrowth that was reversed by pancreatic replacement therapy, indicating that pancreatic secretions can have an important influence on the small intestinal bacterial flora of dogs.
Effect of diet on Heinz body formation in kittens
Authors: Hickman Mary Anne , Rogers Quinton R. , Morris James G. 
Published: January 2024

SUMMARY
Heinz body formation was examined in kittens, in response to consumption of a variety of diets. A commercial salmon-based diet containing 16.5 mg of nitrite, 39 mg of histamine, and 210,000 IU of vitamin A/kg of diet (dry-matter basis) was found to induce Heinz body formation. Purified experimental diets—containing nitrite up to 405 mg/kg; histamine, 50 mg/kg; histamine, 50 mg/kg plus nitrite, 45 mg/kg; or vitamin A, 250,000 IU/kg—failed to induce Heinz body formation.
The effect of propylene glycol (pg) on Heinz body formation was examined by giving groups of 6 kittens purified diets containing 5 or 10% pg for 12 weeks. Two additional kittens were fed a commercial soft-moist diet containing pg for 12 weeks. All kittens fed pg developed Heinz bodies, with peak values for erythrocytes containing Heinz bodies being: 28% for kittens of the 10% pg group; 20% for kittens of the 5% pg group; and 36% for kittens of the soft-moist diet group. Kittens did not develop anemia or methemoglobinemia. Heinz body percentage required 6 to 8 weeks to decrease to the pretreatment value of < 1% after diets containing pg were discontinued.
51Chromium-labeled erythrocytes were used to evaluate erythrocyte survival in 4 kittens of the 10% pg-fed group and in 4 control kittens. Kittens with Heinz body formation induced by 10% pg had significantly (P < 0.001) decreased erythrocyte survival, compared with that for controls, with half-life of 8.3 days for kittens of the pg group, compared with 12.6 days for kittens of the control group.
Diagnosis of nitrate toxicosis in cattle, using biological fluids and a rapid ion chromatographic method
Authors: Boermans Herman J. 
Published: January 2024

SUMMARY
An ion chromatographic method was used to simultaneously determine nitrate and nitrite ions in biological samples. Ultrafiltration was used to produce a proteinfree filtrate. Chloride interferences were eliminated by precipitation as the silver salt. Detection limits and average recoveries were 0.5 mg/L and 102% for nitrate and 0.2 mg/L and 78% for nitrite, respectively. Nitrate concentration was 2.1 ± 1.8 mg/L and 4.9 ± 0.8 mg/L in serum and ocular fluid of healthy cattle, respectively; nitrite was not detected.
A severe case of nitrate poisoning in cattle was described and used to study the concentrations of nitrate and nitrite in samples obtained under natural conditions. Nitrate concentration of acutely poisoned cattle was 35% lower in ocular fluid at 158.1 ± 51.4 mg/L, than in serum at 256.3 ± 113.4 mg/L. Nitrite was not detected, because of the long processing time (> 3 hours) required for samples obtained in the field. A gradual decrease in ocular fluid nitrate of 29.4% at 24 hours, 25.9% at 36 hours, 51.6% at 48 hours, and 73.2% at 60 hours was observed; however, concentrations remained diagnostically significant (73.2 mg/L) 60 hours after death. Twenty-four hours after poisoning, the serum nitrate concentration of severely ill (52.7 ± 51.9 mg/L) and moderately affected (12.4 ± 5.7 mg/L) cattle that survived was indicative of the severity of clinical signs previously observed. Nitrate in serum and ocular fluid was stable in samples stored for 24 hours at 23 C, 1 week at 4 C, and 1 month at −20 C.
Effects of bovine mammary secretion during the early nonlactating period and antibiotics on polymorphonuclear neutrophil function and morphology
Authors: Lintner T. J. , Eberhart R. J. 
Published: January 2024

SUMMARY
The effect of bovine mammary secretion during the early nonlactating period and of antibiotic preparations on bovine polymorphonuclear neutrophil (pmn) phagocytic function and morphology were evaluated in a series of in vitro multifactorial experiments. Benzathine cloxacillin (cl), benzathine cephapirin (ce), sodium novobiocin (no), and a combination of dihydrostreptomycin with procaine penicillin G (dp) were prepared in the presence and absence of a peanut oil aluminum monostearate vehicle. The pmn were isolated from bovine blood, and the effect of each antibiotic preparation on pmn function and morphology was evaluated in a buffer, fat, skim, and a combination of fat with skim from bovine mammary secretion during the nonlactating period. The fat and skim were diluted with buffer to approximate their concentration in mammary secretion. Phagocytic functions of pmn were monitored by fluorescent microscopy, which made it possible to estimate both ingestion and intracellular killing of bacteria by pmn. Changes in pmn morphology were monitored by transmission electron microscopy.
The ability of PMN to ingest and kill Staphylococcus aureus ATCC 25923 was significantly decreased by fat, skim, cl, ce, no, and dp. Effects of some antibiotics on ingestion and killing of bacteria by pmn were influenced by the addition of vehicle and by interactions with mammary secretion. Neutrophil morphology was altered by fat, skim, cl, ce, no, and dp. The detrimental effects of cl, ce, no, and dp on pmn morphology were influenced (some significantly) by the presence of vehicle and interactions with mammary secretion. There were significant correlations among secretion- and antibiotic-induced changes in pmn ingestion of bacteria, pmn killing of bacteria, and pmn morphology.
Anatomy of the laryngeal and adjacent regions as perceived by palpation of clinically normal standing horses
Authors: McCarthy P. H. 
Published: January 2024

SUMMARY
The anatomy of each feature and structure of the laryngeal and adjacent regions, as perceived by palpation, is described for clinically normal standing horses. Visible skin contours produced by some of the superficial structures are also described. Concurrent dissection was performed on fresh cadavers to confirm initial findings. The procedure of systematic palpation in relation to clinical diagnosis and surgical procedure is discussed.
X-ray-computed tomography, nephrotomography, and ultrasonography of the adrenal glands of healthy dogs
Authors: Voorhout George 
Published: January 2024

SUMMARY
X-ray-computed tomography (CT), nephrotomography, and ultrasonography were performed in 10 clinically healthy dogs (weighing 14 to 33 kg) to visualize the adrenal glands. In all 10 dogs, CT enabled visualization of both adrenal glands. Cross-sectional diameter was measured accurately. The size and shape of CT sections of the adrenal glands varied widely because of individual differences in the actual size and shape of the adrenal glands and because of their position in the plane of the CT scans.
In 5 dogs, nephrotomography enabled visualization of 1 or both adrenal glands as oblong craniocaudal-directed densities in the craniodorsal portion of the abdomen. In 7 dogs, transverse ultrasonography enabled visualization of 1 or both adrenal glands as round or oval hypoechoic structures in the surrounding hyperechoic fat.
Evaluation of a commercial staphylococcal bacterin for management of idiopathic recurrent superficial pyoderma in dogs
Authors: DeBoer Douglas J. , Moriello Karen A. , Thomas Chester B. , Schultz Kevin T. 
Published: January 2024

SUMMARY
Twenty-one dogs with idiopathic superficial recurrent pyoderma were entered into a double-blind, placebo-controlled study to evaluate the efficacy of a commercial staphylococcal bacterin. The study spanned an 18-week period. All dogs were administered sodium oxacillin orally for the initial 6 weeks of the study. Dogs were given the bacterin or placebo sc, twice weekly at 3- or 4-day intervals, beginning at week 0 and continuing for 18 weeks. Dogs given antibiotics plus the bacterin (n = 13) hada significantly (P < 0.05) better treatment response than those given antibiotic plus placebo.
Study of long-term survival after transsphenoidal hypophysectomy in clinically normal dogs
Authors: Niebauer Gert W. , Eigenmann Joseph E. , Van Winkle Thomas J. 
Published: January 2024

SUMMARY
Experimental hypophysectomies were performed in 7 clinically normal dogs, using a new modification of the transsphenoidal approach. This approach facilitated centering of the sphenoid bone trephination and allowed safe exposure of the hypophysis regardless of the size or shape of a dog's skull. Complications did not occur during surgery and all dogs recovered well from surgery. Growth hormone secretory capacity was measured over a 3-month period to assess completeness of hypophysectomies. One dog was euthanatized 2 months after surgery, 4 dogs were euthanatized at 3 months after surgery, and 2 dogs were allowed to survive and their progress was followed for 2.5 years. Soft palate dehiscence and keratoconjunctivitis sicca developed in 2 of the dogs. The technical deficiencies responsible for these complications were corrected shortly after the beginning of the study. In 4 of the 5 necropsied dogs, minute remnants of adenohypophyseal tissue were found in the sellae turcicae. Measurement of in vivo growth hormone secretory capacity revealed that these remnants had an altered stage of functional activity. Although complete hypophysectomy was not achieved consistently, the main technical obstacle of hypophysectomy, the reliable identification and the avoidance of the vascular structures surrounding the hypophysis, has seemingly been overcome. The surgical technique proved to enhance the safety of hypophysectomy, and the procedure can be recommended to treat clinical cases of canine pituitary-dependent hyperadrenocorticism. The clinical significance of potential subtotal hypophysectomy remains yet to be evaluated.
Range of viral neutralizing activity and molecular specificity of antibodies induced in cattle by inactivated bovine viral diarrhea virus vaccines
Authors: Bolin Steven R. , Ridpath Julia F. 
Published: January 2024

Summary
The range of neutralizing activity to bovine viral diarrhea (bvd) virus and viral protein specificity of antibodies induced by 3 inactivated vaccines were evaluated by use of samples of sera obtained from 13 cattle 14 days after vaccination. Viral neutralizing antibodies were detected in all cattle to each of 10 noncytopathic and 10 cytopathic isolates of bvd virus. A viral-induced polypeptide (53,000 to 56,000 daltons) was detected by radioimmunoprecipitation with serum from all vaccinates. Other viral-induced polypeptides of 115,000, 80,000, 48,000, and 25,000 daltons were precipitated with sera from some vaccinates. Precipitation of those polypeptides was related to the vaccine used. When multiple viral polypeptides were precipitated, the 53,000- to 56,000-dalton polypeptide appeared immunodominant.
Characterization of an attenuated strain of Actinobacillus pleuropneumoniae, serotype 1
Authors: Rosendal S. , MacInnes J. I. 
Published: January 2024

Summary
Pleuropneumonia is an important disease of swine caused by Actinobacillus pleuropneumoniae. Putative virulence determinants include capsule, lipopolysaccharide, and cytotoxin. We studied the virulence and virulence determinants of 2 strains: CM5 and CM5A of serotype 1. Strain CM5 was isolated from a pig with pleuropneumonia and passaged once in vitro; strain CM5A was a substrain of CM5 passaged 70 times in vitro. Pigs challenge exposed to an aerosol of 1.3 × 107 colony-forming units of CM5/ml died within 30 hours; pigs challenge exposed to an aerosol of 1.6 × 108 colony-forming units of CM5A/ml survived. The average thickness of the capsular layer was 137 nm in strain CM5 and 53 nm in strain CM5A in bacteria treated with homologous antibody and examined by transmission electron microscopy. Similarly, capsular material binding polycationic ferritin was found in colonies of strain CM5, but not in strain CM5A. The ratio of hexosamine to protein in extracted capsule of CM5 was more than twice that of CM5A.
The polyacrylamide gel electrophoretic profile of the lipopolysaccharide, outer membrane proteins, and whole cell proteins did not differ between the 2 strains. Also, the amount of cytotoxin or endotoxin produced by the 2 strains during the logarithmic growth phase was not different. The electrophoretic profile of restriction endonuclease digested dna was similar, with the exception of bands in the 750- and 620-basepair regions. It was concluded that attenuation of strain CM5A during in vitro passage was a result of reduced capsule production and that encapsulation is an important virulence determinant of A pleuwropneumoniae, serotype 1.