bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of COVID-19 infection on social care use in people over 50 years of age: a matched cohort study
Authors: Butfield Rebecca , Bray Benjamin D , Quint Jennifer , Castanon Alejandra , Adesanya Elizabeth , Chen Simon , Russell Rachel 
Published: February 2025

AbstractObjectivesTo estimate the impact of COVID-19 infection on the requirement for social care services among adults aged ≥50 years in North-West London.DesignPopulation based matched cohort study using linked routinely collected electronic social care, primary care and hospital records (the Discover dataset).SettingApproximately 4.7 million people with a general practitioner record in North-West London.Participants150,654 adults aged ≥50 years with a first diagnosis of COVID-19 between January 2020 and February 2023 and 547,704 propensity score matched comparators without a COVID-19 diagnosis during the same period.Main outcome measuresSocial care use and associated costs overall and by specific type (care home, domiciliary care, respite care, social care assessments) stratified by age group, index year, diagnosis setting, severe COVID-19 risk status, frailty, and care home admission prior to index. Overall survival.ResultsA total of 9,174 (6.09%) individuals with COVID-19 required social care use (of any type) during follow up, 2.54 times (95%CI: 2.48-2.61; P<0.0001) higher than matched comparators (n=13,126, 2.40%). The difference was largest for care home admission; individuals with COVID-19 had 4.10 (95%CI: 3.87-4.36; P<0.0001) times the risk of a care home admission and nearly twice the risk (risk ratio 1.94; 95%CI:1.86-2.02 P<0.0001) of domiciliary care during follow up compared with matched comparators. Individuals with COVID-19 experienced higher mortality, with 9.30% (14,005/547,704) dying during follow up compared with 3.76% (20,608/547,704) deaths among matched comparators.This increase in social care utilisation was observed for all age groups. Adults with COVID-19 had over four times higher social care costs than matched comparators (£1,276 per person per year (pppy) versus £276 pppy; mean difference +£1000, 95%CI: £947-£1054, p<0.0001), with most of the costs due to care home admissions. Higher social care costs in individuals with COVID-19 compared with matched comparators were strongly age related, rising from a mean difference of £130 pppy (95%CI: £99-£161) in those aged 50-64 to £6108 pppy (95%CI: £5613-£6603) higher costs in those aged ≥ 85.ConclusionsCOVID-19 infection is associated with meaningfully higher social care requirements in the ≥50 years population. Reducing the need for social care use and the associated costs of care should be one of the goals of interventions to reduce the risk and severity of COVID-19 infection.
Limited response of primary nasal epithelial cells toBordetella pertussisinfection and the effector protein BteA
Authors: Zmuda Martin , Pravdova Barbora , Malcova Ivana , Cerny Ondrej , Vondrova Denisa , Kamanova Jana 
Published: February 2025

AbstractBordetella pertussisis a Gram-negative coccobacillus that causes whooping cough or pertussis, a respiratory disease that has recently experienced a resurgence. Upon entering the respiratory tract,B. pertussiscolonizes the airway epithelium and attaches to ciliated cells. Here, we used primary human nasal epithelial cells (hNECs) cultured at the air-liquid interface, and investigated their interaction with theB. pertussisB1917, focusing on the role of the type III secretion system effector protein BteA. In this model, which resembles the epithelial cells of nasal epitheliumin vivo,B. pertussisB1917 initially replicated in the overlying mucus and scarcely colonized the cell cilia. The colonization led to a gradual decline in epithelial barrier function, as shown by measurements of trans-epithelial electrical resistance (TEER) and staining of the tight junction protein zonula occludens 1 (ZO-1). The decrease in TEER occurred independently of the cytotoxic effector protein BteA. Transcriptomic and proteomic analyses of hNECs showed only moderate changes following infection, primarily characterized by increased mucus production, including upregulation of mucin MUC5AC. No profound response to BteA was detected. Furthermore, the infection did not induce production of inflammatory cytokines, suggesting thatB. pertussisB1917 evades recognition by hNECs in this model system. These findings suggest that the bacterium may utilize the mucus layer in the airways as a protective niche to minimize epithelial recognition and damage.ImportanceThe nasal epithelium is the initial site whereB. pertussiscomes into contact with the host during respiratory infection. This work established human nasal epithelial cells (hNECs) cultured at the air-liquid interface (ALI) as anin vitromodel to investigateB. pertussisinfection. Using this system, we were able to show that in the early stages of colonization the clinical isolateB. pertussisB1917 replicates in the mucus without disrupting epithelial barrier function. Infection results in moderate transcriptomic and proteomic changes and is characterized by increased mucus production and minimal inflammatory signaling.
A scoping study of the whole-cell imaging literature: a foundational corpus, potential for data-mining and research synthesis, and a call for standardization of an emerging field
Authors: Mirvis Mary , Weingard Brooke , Goodman Steven , Marshall Wallace F. 
Published: February 2025

ABSTRACTThe level of cellular organization bridging the mesoscale and whole-cell scale is coming into focus as a new frontier in cell biology. Great progress has been made in unraveling the complex physical and functional interconnectivity of organelles, but how the entire organelle network spatially arranges within the cytoplasm is only beginning to be explored. Drawing on cross-disciplinary research synthesis methods, we systematically curated the whole-cell volumetric imaging literature through 3 rounds of screening involving 3 independent reviewers, resulting in 89 top hits and 38 “borderline” studies. We describe the trajectory and current state of the field (2004-2024). A broad characterization, or “scoping review”, of bibliometrics, study design, and reporting practices shows accelerating technological development and research output. We find high variability in study design and reporting practices, including imaging modality, model organism, cellular contexts, organelles imaged, and analyses. Due to the laborious, low-throughput nature of most volumetric imaging methods, we find trends toward small sample sizes (<30 cells) and small cell types. We find common quantitative analyses across studies, including volumetric ratios of organelles and inter-organelle contact analyses. Our curated dataset now enables future aggregate and comparative analyses to potentially reveal larger patterns and generate more generalized hypotheses. This work establishes a growing dataset of whole-cell imaging literature and data, and motivates a call for standardized whole-cell imaging study design, reporting, and data sharing practices. More broadly, we showcase the potential of new rigorous secondary research methods to strengthen cell biology’s literature review and reproducibility toolkit, create a new avenues for discovery, and promote open research practices that support secondary data-reuse and integration.
Trajectories of persistence in exporting: a capability approach
Authors: Losada-Otálora Mauricio , Escandón-Barbosa Diana , Salas-Páramo Jairo , Peña-García Nathalie 
Published: February 2025

Purpose
The purpose of this paper is answering two research questions: What are the trajectories of persistence in exporting followed by different groups of firms? What factors relate to each trajectory of persistence in exporting? The authors propose and test a framework that links operational and marketing firms’ capabilities to different trajectories of persistence in exporting.

Design/methodology/approach
Using a dataset of 2,913 firms over 14 years from the annual manufacturing survey in Colombia (AMS), the authors explored the trajectories of persistence in exporting. The authors applied data envelopment analysis to measure operational and marketing capabilities and group-based trajectory modeling to discover and link such trajectories to firms’ capabilities.

Findings
The authors identified four trajectories of persistence in exporting. Also, the authors found that while the interplay between marketing and operational capabilities relates positively to the non-exporting trajectory and negatively to the persistent trajectory, operational capabilities relate positively to the erratic trajectory and negatively to the slow growth trajectory of persistence in exporting. Meanwhile, marketing capabilities do not relate to any trajectory.

Research limitations/implications
Policymakers should help firms develop marketing and operational capabilities to compete globally to motivate them to export and persist in exporting. Policymakers should avoid stimulating firms to reinforce learned and familiar capabilities that cannot leverage desirable trajectories of persistence in exporting.

Originality/value
The authors introduce the trajectories of persistence in exporting, providing a fresh perspective for analyzing exporting behavior over time. The authors have also proposed and tested a unique framework that links operational and marketing firms’ capabilities to these trajectories, thus contributing to the existing body of knowledge on exporting behavior by firms from emerging markets.
Disabled individuals facing and reacting against identity threat during school-to-work transition
Authors: Richard Sarah , Grima François 
Published: February 2025

PurposeIn a context in which disabled people are stigmatized, the school-to-work transition threatens the occupational identity to which disabled individuals aspire. This study highlights how students with a disability face and react against identity threat, using identity management strategies and, specifically, identity threat responses when intending to integrate into the workplace.Design/methodology/approachStudents in transition or having recently integrated into the workplace were interviewed to relate their transitioning experience, resulting in a qualitative study based on 31 semi-structured interviews.FindingsThe study reveals that identity threat is experienced during the school-to-work transition process and that disabled individuals do not remain passive but actively fight against it. The participants used four identity management strategies to attempt to counteract such threats. The strategies displayed include identity threat mechanisms such as identity-protection and identity-restructuring responses. The outcomes of these strategies are presented in terms of their positive and backlash effects.Originality/valueThis research contributes to the identity management literature and, more specifically, to the identity threat literature by showing how disabled individuals combine several identity threat responses, which they use as resources to reduce potential harm. New identity threat responses that are particularly crucial in a career management strategy are also highlighted.
Enhancing cognitive metrics in supply chain management through information and knowledge exchange
Authors: Żywiołek Justyna , Mathiyazhagan Kaliyan , Shahzad Umer , Zhao Xin , Saikouk Tarik 
Published: February 2025

PurposeThis research primarily aims to investigate the impact of organizational implants on knowledge transmission, process innovation and security integration in intricate supply chains.Design/methodology/approachThe research utilizes a mixed-method approach, employing a stratified sampling strategy to get a representative sample of 1,284 enterprises from various sectors within the logistics industry within the European Union. Data were gathered by computer-assisted web interviewing (CAWI) and analysed utilizing structural equation modelling (SEM) to evaluate hypotheses concerning cognitive congruence, process diffusion and security integration.FindingsThe results indicate that while task interdependence clearly improves face-to-face communication, excessive cognitive congruence can hinder process innovation, resulting in what the article terms “cognitive rigidity.” The study suggests that achieving a balance between cognitive congruence and cognitive flexibility is crucial to improving the safety diffusion and integration process.Originality/valueThis study presents an innovative conceptual framework that synthesizes cognitive congruence, cognitive flexibility and cognitive rigidity to examine their combined influence on knowledge transfer and process dissemination throughout supply chains. It presents cognitive stiffness as a boundary condition, contesting the conventional belief that more cognitive congruence is invariably advantageous.
Unveiling risk management dynamics in family businesses through a bibliometric analysis
Authors: Madonna Salvatore , Cestari Greta , Georgiev Mario Georgiev 
Published: February 2025

PurposeThe purpose of this research is to offer an updated picture of the academic state-of-art of the literature about risk management in family businesses. Furthermore, the study aims to outline possible future stream of research, being a helpful resource for future scholars.Design/methodology/approachResearch using an integrative view, encompassing both bibliometric analysis and manual review has been conducted. The data were collected from Scopus and Web of Science databases.FindingsThe key findings highlight that family businesses, despite their importance to the global economy, often neglect risk management, exposing themselves to significant risk factors. The analysis shows an increase in scientific production on this topic in recent years but emphasizes the need for further research, especially in different cultural contexts and with both quantitative and qualitative methods. The document also suggests that both informal and formal risk management practices should be studied more thoroughly to better understand the interaction between social capital and governance structures in family businesses.Research limitations/implicationsThe study’s limitations include reliance on two databases and English-language articles only. Additionally, excluding non-peer-reviewed materials and narrow keyword selection may have impacted the findings.Originality/valueThis study offers an updated view of the literature of the last years highlighting the latest trends. The article offers suggestions for future research to guide investigations into currently under-represented areas.
The use of publicly available online texts in training AI: an ethical analysis of AI’s right to learn
Authors: Rahal Louai 
Published: February 2025

Purpose
This paper aims to discuss the ethical permissibility of using publicly available online texts in the training of AI. This practice has facilitated and accelerated the growth of AI technology, but it has also drawn accusations of exploiting authors and violating their intellectual property rights.

Design/methodology/approach
The discussion is based on the Kantian theory of ethics, a theory that is grounded in the duty to preserve and empower the autonomy of the human will.

Findings
Following from the duty to support human autonomy, the article makes two claims: First, AI should be granted the right to learn from public texts because the more AI learns, the better it assists humans in expanding their will. Second, AI’s right to learn should be conditional, not absolute. The article articulates three conditions that should be met prior to granting an AI system the right to learn from public texts: AI that uses public data must be freely available to the public, AI (and its developers) ought to educate the public on the uses and misuses of AI, and AI (and its developers) must remove personal information from the training data.

Originality/value
Under what conditions is it justifiable to use someone’s text without their permission? This very question is currently being examined in courts in the many lawsuits filed against AI companies. An ethical analysis of this question helps bridge the gap between the perspective of AI companies that claim to be using public texts for the public good and the perspectives accusing them of violating authors’ copyrights.
Identifying thematic clusters of ESG in contemporary accounting studies through systematic literature review
Authors: Paolone Francesco , Bitbol-Saba Nathalie 
Published: February 2025

Purpose
This study aims at identifying the most relevant thematic clusters of studies at the intersection of accounting and environmental, social and governance (ESG), the potential benefits and impacts that research clusters may have at a systemic level on Sustainable Development Goals and factors that could enhance these benefits and impacts.

Design/methodology/approach
This research is based on a systematic literature review approach using a descriptive bibliometric method, data analysis visualization and thematic analysis to fully investigate the content of studies in the accounting domain seeking to achieve research aims, providing insights, critiques and future research paths.

Findings
This study delves into the evolving landscape where ESG intersects with accounting. It aims to provide valuable insights into the multifaceted relationship between ESG and accounting. The authors identify three thematic clusters: ESG accounting data and investment decision-making, firm’s CSR and ESG issues and ESG and sustainability and accountability.

Originality/value
To the best of the authors’ knowledge, this is the first study that integrates bibliometric and literature review analyses to provide a comprehensive outlook of the benefits and impacts ESG and interdisciplinary accounting research can have on the environment and society.
Structural diversity is an important predictor of forest productivity responses to drought
Authors: Murray Samantha J. , Will Rodney E. , Gholizadeh Hamed , Joshi Omkar , Zhai Lu 
Published: February 2025

Abstract

The response of forest productivity to drought depends on biodiversity and other stand attributes. Biodiversity can regulate productivity through niche complementarity (i.e. greater diversity better utilizes resources to determine ecosystem functioning) and mass‐ratio effects (i.e. dominance drives ecosystem functioning). However, when these forest attributes occur with drought, stress results are mixed. One emerging biodiversity metric is structural diversity, the variation in vegetation size and form. There is a lack of understanding of the interactive effects of structural diversity and drought on forest productivity. Addressing these knowledge gaps can improve the projection of forest dynamics and structural diversity‐based management for drought adaptation.

We compiled multiple datasets including repeated survey data of 13,059 trees in 299 plots across southcentral US forests stressed by the 2010–2015 drought. We used the Random Forest algorithm to examine how structural diversity and other factors influenced three aspects of productivity measured by above‐ground wood biomass: ingrowth, growth, and net change accounting for mortality.

Our results showed that (1) Among the eight stand attributes studied, structural diversity was among the top three variables showing the greatest main and interactive effects of drought on forest productivity, except for the interactive effect on ingrowth; (2) The drought‐related losses in forest growth and biomass net change were exacerbated in forests with greater structural diversity; (3) Compared with the species and functional diversity metrics, functional identities had greater interactive effects with drought on forest productivity (except for the ingrowth).

Synthesis and applications: Productivity losses related to drought increased with greater structural diversity and decreased with functional identities characterized by conservative resource strategies, such as a high leaf carbon–nitrogen ratio. Thus, structural diversity and functional identity could be considered in projecting and managing forest dynamics under climate change. The comparisons between functional identity and the diversity metrics support the important role of the mass‐ratio effect in forest productivity during drought.
The role of residual (veterinary) antibiotics in chemical exposome analysis: Current progress and future perspectives
Authors: Hossain Md Zakir , Feuerstein Max L. , Warth Benedikt 
Published: February 2025

AbstractHumans are exposed to a complex mixture of environmental and food‐related chemicals throughout their lifetime. Exposome research intends to explore the nongenetic, that is, environmental causes of chronic disease and their interactions comprehensively. Residual antibiotics can enter the human body through therapeutics, foods of animal origin, aquatic products, or drinking water. In the last decade, significant levels of residual antibiotics in human urine have been described, demonstrating frequent exposure throughout populations. To which extent they contribute to human health risks is debated. Human biomonitoring (HBM) aims to determine and quantify concentrations of xenobiotics in human specimens and provides the toolbox to monitor exposure to diverse chemical exposures. Due to their public health implications, priority‐listed xenobiotics are routinely monitored in the European Union and other countries. However, antibiotics, an important class of (food‐derived) xenobiotics, are still not systematically investigated for a better and more holistic understanding in the context of exposomics. This review provides a comprehensive summary of HBM research related to antibiotics, existing liquid chromatography–mass spectrometry (LC–MS)‐based analytical methods, and potential health risks caused by unintended exposure. Incorporating antibiotics into the chemical exposome framework through routine HBM using multiclass analytical methods will provide a better understanding of the toxicological or pharmacological mixture effects and, ultimately, the chemical exposome.
Impact of bifenthrin and clothianidin on blow fly (Diptera: Calliphoridae) oviposition patterns under laboratory and field conditions
Authors: Rivera‐Miranda Teomie S. , Hans Krystal R. 
Published: February 2025

AbstractBlow flies (Diptera: Calliphoridae) can detect decomposing remains and begin colonizing the resource through oviposition soon after. The estimated time between colonization and insect evidence collection is referred to as the time of colonization (TOC). Forensic entomologists use the TOC to help estimate the minimum postmortem interval (mPMI), or the time between death and the discovery of remains. The presence of insecticides can influence blow fly behaviors, including oviposition. This study aimed to investigate how different concentrations of two insecticides, bifenthrin and clothianidin, affected blow fly oviposition both under laboratory and field conditions. In the laboratory experiments, Lucilia sericata (Meigen) and Phormia regina (Meigen) blow flies were exposed to beef liver treated with varying concentrations of bifenthrin or clothianidin. In the field, stillborn pig carcasses were treated with the same concentrations and time to oviposition was assessed and oviposition site preference observed. Insecticides have the potential to deter insect activity. Therefore, we hypothesized that insecticide exposure would result in delayed oviposition, altered site preferences, and increased mortality due to their modes of action. Statistical analyses indicated that the insecticides had no significant effects on the time to oviposition in the laboratory experiments, although species‐ and insecticide‐specific effects were observed. Clothianidin, however, significantly affected mortality rates in both species. During field trials, bifenthrin significantly delayed oviposition, while clothianidin inhibited oviposition at the high concentration. These findings offer valuable insights for improving entomological evidence analysis in criminal investigations where insecticide exposure is suspected.