bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identifying neonatal intensive care (NICU) admissions using administrative claims data
Authors: Vance A.J. , Bell S. , Tilea A. , Beck D. , Tabb K.M. , Zivin K. 
Published: December 2023

BACKGROUND: To define a method for identifying neonatal intensive care unit (NICU) admissions using administrative claims data. METHODS: This was a retrospective cohort study using claims from Optum’s de-identified Clinformatics® Data Mart Database (CDM) from 2016 –2020. We developed a definition to identify NICU admissions using a list of codes from the International Classification of Diseases, 10 th Revision, Clinical Modification (ICD-10-CM), Current Procedural Terminology (CPT), and revenue codes frequently associated with NICU admissions. We compared agreement between codes using Kappa statistics and calculated positive predictive values (PPV) and 95% confidence intervals (CI). RESULTS: On average, revenue codes (3.3%) alone identified more NICU hospitalizations compared to CPT codes alone (1.5%), whereas the use of CPT and revenue (8.9%) and CPT or revenue codes (13.7%) captured the most NICU hospitalizations, which aligns with rates of preterm birth. Gestational age alone (4.2%) and birthweight codes alone (2.0%) identified the least number of potential NICU hospitalizations. Setting CPT codes as the standard and revenue codes as the “test,”, revenue codes resulted in identifying 86% of NICU admissions (sensitivity) and 97% of non-NICU admissions (specificity). CONCLUSIONS: Using administrative data, we developed a robust definition for identifying neonatal admissions. The identified definition of NICU codes is easily adaptable, repeatable, and flexible for use in other datasets.
Pembuatan Grease Dari Palm Fatty Acid Distillte (PFAD) dengan Variasi Komposis Base Oil, Thickening Agent dan Asam Asetat Sebagai Zat Aditif
Authors: Pratiwi Ryu Indah , Junaidi Robert , Meidinariasty Anerasari 
Published: December 2023

Substitusi minyak bumi dengan nabati sebagai bahan pelumas dilakukan untuk menghasilkan minyak pelumas yang ramah lingkungan. PalmÂ FattyÂ AcidÂ DistillateÂ (PFAD) menjadi salah satu produk turunan minyak kelapa sawit yang dapat dimanfaatkan sebagai bahan pembuatan grease. GreaseÂ adalah bahan semi padatan campuran antara minyak baseÂ oilÂ dengan bahan pengentalnya (ThickeningÂ Agent) yang berfungsi mengurangi gesekan dan keausan antara dua bidang yang saling bergesekan. penelitian ini bertujuan untuk mendapatkan karakteristik greaseÂ menurut SNI dan mendapatkan tingkat NLGI terbaik. Penelitian ini dilakukan dengan komposisi antara baseÂ oilÂ dan thickeningÂ agent dan zat aditif.Â Grease terbaik yang diperoleh termasuk dalam spesifikasi greaseÂ dan parameter kinerja untuk tingkat kualitas NLGI grade A dengan formulasi baseÂ oil : thickeningÂ agent 80:20 dengan penambahan zat aditif 3,5 ml, densitas 0,9057 gr/ml dan droppingÂ point 98Â°C yang telah sesuai dengan SNI dengan penetrasi 241 mm yang mengindikasikan grease ke dalam kelas NLGI 3Â
Review of Belfast Punk and the Troubles: An Oral History, by Fearghus Roulston
Authors: Gemrichová Marie 
Published: December 2023

Review of Belfast Punk and the Troubles: An Oral History, by Fearghus Roulston (Manchester: Manchester University Press, 2022), 208 pp., ISBN: 978-1-5261-5223-7, £85.00 (Hardcover)
Pengaruh Motivasi, Literasi Keuangan, Dan Demografi Terhadap Perencanaan Keuangan Untuk Mencapai Kebebasan Keuangan
Authors: Raharjo Magda Endrica , Santoso Bambang Hadi , Satrio Budhi 
Published: December 2023

Perencanaan keuangan merupakan langkah awal untuk mencapai kebebasan keuangan guna mencakup tujuan keuangan yang perlu dicapai. Skor indeks kesehatan keuangan pada masyarakat Indonesia masih relatif rendah, hanya sebesar 37,72 dari skor maksimal 100, hal ini semakin menegaskan bahwa literasi keuangan sangat penting bagi masyarakat yang ingin mencapai kebebasan keuangan. Tujuan penelitian ini untuk mengetahui pengaruh motivasi, literasi keuangan, dan demografi terhadap perencanaan keuangan keluarga dan kebebasaan keuangan. Populasi penelitian ini adalah investor PT. XYZ Sekuritas Surabaya. Penentuan sampel menggunakan metode non probability sampling dengan jumlah sampel sebanyak 180. Teknik analisis menggunakan partial least square. Hasil penelitiaan ini memperlihatkan motivasi, literasi keuangan, dan demografi berpengaruh signifikan terhadap perencanaan keuangan dengan p value 0,000. Motivasi,dan literasi keuangan, berpengaruh signifikan terhadap kebebasan keuangan melalui mediasi perencanaan keuangan dengan p value 0,000 dan 0,046. Saran penelitian selanjutnya dapat menambahkan variabel lain yang diduga dapat mengidentifikasi Self Control, serta faktor dari demografi seperti pendapatan dan juga jumlah anggota keluarga.
Sistem Audit Teknologi Informasi Berdasarkan Cobit Untuk Menilai Level Of Maturity Berbasis Web
Authors: Chotijah Umi 
Published: December 2023

Teknologi informasi dan komunikasi (TIK), tak dapat dipungkiri, memainkan peran yang penting dalam agenda transformasi tiap perusahaan. Tak terkecuali bagi Semen Indonesia Group (SIG) yang membutuhkan dukungan operasional untuk digitalisasi proses bisnis dan penunjang kegiatan operasional sistem informasi perusahaan. Saat ini, teknologi informasi atau sistem informasi yang ada pada PT. SIG dikelola oleh Department of ICT. Department of ICT atau unit departemen pelayanan ICT, merupakan sebuah departemen perusahaan yang bertanggung jawab dalam mengelola teknologi informasi atau sistem informasi pada PT. SIG, Jika tidak memiliki tingkat penanganan yang tepat, teknologi informasi seperti itu tentu memiliki risiko-risiko yang tidak dapat dihindari, untuk mengatasi hal tersebut diperlukan tata kelola terhadap penggunaan teknologi informasi atau sistem informasi. Beberapa permasalahan yang ada antara lain adanya kesulitan atau kendala yang dialami oleh auditor dalam melakukan audit teknologi atau sistem informasi pada departemen pelayanan ICT karena masih menggunakan metode konvensional dalam lingkungan pemrosesan data elektronik. Penelitian ini bertujuan merancang dan membangun sistem audit teknologi informasi sesuai dengan standar COBIT 5.1 yang dapat mendukung kerja auditor dalam kegiatan audit teknologi informasi. Rancang bangun sistem audit teknologi informasi berbasis web menghasilkan suatu aplikasi Audit Teknologi Informasi Berbasis web dimulai dari pembuatan flowchart sistem lalu pembuatan data flow diagram (DFD) dan entity relationship diagram (ERD). Sistem pemilihan yang dibangun melibatkan auditor sebagai entitas luar. Rancang bangun sistem audit teknologi informasi berbasis web menghasilkan suatu aplikasi Audit Teknologi Informasi Berbasis web menggunakan Maturity Level tools yang terdapat dalam Framework COBIT 5.1. Desain aplikasi ini berbentuk Radio Button dengan acuan hasil pemetaan Proses Teknologi Informasi berdasarkan COBIT 5.1. Aplikasi ini Membantu auditor dalam mengevaluasi informasi hasil audit dan membantu auditor dalam melakukan analisis hasil Audit. Metode yang digunakan dalam pengembangan membangun sistem audit teknologi informasi adalah waterfall. Berdasarkan hasil implementasi dan pengujian, sistem audit teknologi informasi telah sesuai dan memenuhi persyaratan fungsional yang telah ditentukan dari proses pengujian.
Pengoptimalan Performa Database Pada Proses Transformasi Data Pada SQL Server
Authors: Setiya Budi Desi , Syahrial Hadi 
Published: December 2023

Database sendiri secara umum adalah kumpulan data yang disimpan secara sistematis di dalam komputer yang dapat diolah atau dimanipulasi menggunakan perangkat lunak (program aplikasi) untuk menghasilkan informasi. Pendefinisian database meliputi spesifikasi berupa tipe data, struktur data dan juga batasan-batasan pada data yang akan disimpan. Salah satu tools yang sering digunakan adalah SQL Server. Pengolahan data sendiri membutuhkan waktu yang tidak sedikit melalui berbagai tahapan. Saat tahapan proses data ada yang disebut dengan transform data dan transfer data. Yang artinya data dikirim dari proses A ke Proses B dan diubah. Dalam hal ini bukan informasi dari sebuah data, namun yang diubah bukan isi atau nilai yang ada di dalamnya, namun merubah manjadi bentuk informasi yang dapat dengan mudah diterima dan dibaca oleh pembaca informasi. Pada proses transform dan transfer, ada beberapa kendala yang dialami. Yang sering terjadi adalah masalah waktu. Waktu merujuk pada kecepatan sebuah proses data itu sendiri. Karena apabila setiap proses memilik kecepatan yang sangat lamban itu akan memakan banyak waktu, padahal masih banyak proses lain yang harus berjalan. Pada penelitian ini, penggunaan teknik Indexing, Temporary Table dan gabungan antara keduanya dilakukan. Guna mendapatkan hasil mana yang lebih cepat untuk digunakan. Pada penelitian ini menggunakan metode True Experiment Design dengan rancangan pengukuran berulang. Yang mana pada penelitian ini akan mendapati beberapa perlakuan, dan dilakukan denga lebih dari satu kali percobaan.
Pengaruh Harga, Produksi dan Kualitas Emping Melinjo Aceh Terhadap Kepuasan Konsumen
Authors: Supristiwendi Supristiwendi , Marlita Yenni , Anzhita Silvia 
Published: December 2023

Persaingan bisnis emping melinjo Aceh sangat ketat tingkat lokal maupun regional. Tujuan penelitian adalah untuk menganalisis tingkat kepuasan konsumen dan pengaruh harga dan kualitas terhadap kepuasan konsumen emping melinjo Aceh. Teknik pengambilan sampel penelitian dilakukan dengan metode “snowball sampling”. Metode analisis data yang digunakan yaitu: analisis kepuasan konsumen menggunakan indeks kepuasan CSI (Costumer Satisfaction Index) dan analisis Structural Equation Modelling (SEM) dengan pendekatan Partial Least Square (PLS). Konsumen merasa sangat puas terhadap atribut rasa dan kualitas emping melinjo Aceh. Indikator harga yaitu; keterjangkauan, kesesuaian, harga bersaing dan manfaat benar-benar mencerminkan atribut harga. Indikator rasa, keawetan, mudah diolah dan tekstur benar-benar mencerminkan atribut kualitas. Indikator terus membeli, terus konsumsi dan rekomendasi benar-benar mencerminkan atribut kepuasan konsumen. Atribut harga tidak berpengaruh terhadap kepuasan konsumen dan atribut kualitas berpengaruh positif dan signifikan terhadap kepuasan konsumen emping melinjo Aceh.
Kanun Tanah Wakaf Negara: Adakah Satu Keperluan
Authors: Sulaiman Abdul Aziz , Zainuddin Noor Hidayah 
Published: December 2023

Semenanjung Malaysia masih menggunapakai KTN sebagai rujukan dalam pelbagai urusan tanah wakaf. Urusan pendaftaran hak milik tanah wakaf juga menggunakan pakai kaedah seperti ditetapkan dalam seksyen 416C KTN. Namun, seksyen ini hanya menetapkan MAIN sebagai pengelola dan pengurus tanah wakaf dan bukannya sebagai pemilik tanah wakaf. Kesannya, tanah wakaf boleh diambil oleh PBN untuk tujuan pembangunan sedangkan tanah wakaf tidak boleh dijual, dihibahkan atau ditukar hak milik. Disinilah perlunya Kanun Tanah Wakaf Negara diwujudkan bagi rujukan perundangan tanah wakaf.
Kata kunci: Kanun Tanah Wakaf Negara, undang-undang, tanah, wakaf, hak milik.

Peninsular Malaysia still uses Land Code 1965 as a reference in various matters of waqf land. The matter of registration of waqf land title also uses the method as prescribed in section 416C Land Code. However, this section only designates MAIN as the organizer and manager of waqf land and not as a waqf land title. As a result, waqf land can be acquired by PBN for development purposes whereas waqf land cannot be sold, given or converted. This is where the National Waqf Land Code is established for the legal reference of waqf land.
Keywords: National Waqf Land Code, law, land, waqf, title.
Reading the Older People Researches in Architecture through Bibliometric Analysis (1975-2022)
Authors: Midilli Sarı Reyhan , Eyüboğlu Hande 
Published: December 2023

The increase in the elderly population all over the world has made it necessary for many disciplines, from health to psychology, from economics to humanities, to conduct field-oriented studies. Architecture is one of the disciplines that play an important role in old age in terms of its relationship with the built environment. This study aims to reveal the intellectual structure, research topics, and trends of scientific studies on elderly users in the discipline of architecture. In this study, in which bibliometric analysis of articles for older adults was made in the Web of Science database between 1975 and 2022, the structure of the field and relations were analyzed by creating science maps through performance analysis and VOSviewer software. In the analyzes made, it has been seen that the number of articles on the elderly has increased in recent years. Although it has a wide distribution in terms of subject variety; housing, aging in place, age-friendly environment, and accessibility are the current topics in the field. This study contributes to the literature by presenting the current course of elderly user-oriented studies in architecture from a bibliographic perspective. On the other hand, it is thought to be a guide for new research by revealing the deficiencies in the field.
Bilateral abducens nerve palsy from post-spinal-anesthesia-induced bilateral chronic subdural hematoma: case report
Authors: Shiferaw Mestet Yibeltal , T/Mariam Tsegazeab Laeke , Aklilu Abenezer Tirsit , Shumbash Kibruyisfaw Zewudie , Akililu Yemisirach Bizuneh , Worku Bethelhem Yishak , Ayele Mengistu 
Published: December 2023

BackgroundA chronic cranial subdural hematoma arising after post-spinal anesthesia is a rare but serious and life-threatening complication of spinal anesthesia. It usually mimics the typical post-spinal-anesthesia headache or post-dural-puncture headache, potentially masking its detection. Abducens nerve palsy tends to occur in chronic subdural hematoma of post-dural-puncture etiology rather than in cases attributed to other causes of subdural hematoma. Preferential damage to the abducens nerve is frequent and can be attributed to its anatomic course because the abducens nerve runs in the direction of the typical caudad displacement of the brain related to intracranial hypotension.ObservationHere, we present a report on the clinical presentation, pathogenesis, and management of two cases that developed bilateral abducens nerve palsy following post-spinal anesthesia administered for cesarean sections due to obstetric indications.LessonPost-spinal-anesthesia-induced chronic subdural hematoma, although a rare, life-threatening complication, must be differentiated from post-spinal-anesthesia headache and treated surgically. Cranial nerve palsy (more commonly called abducens nerve palsy) is more common in post-spinal-anesthesia-induced subdural hematoma than subdural hematomas of other etiologies as the cerebrospinal fluid brain cushioning is partly lost. Cranial nerve palsies resolve in most cases if surgery is performed in a timely manner.
Bibliometric analysis of global research trends in adeno-associated virus vector for gene therapy (1991-2022)
Authors: Jiang Fengqi , Zhang Chuanhe , Liu Weina , Liu Fangyuan , Huang Haiyan , Tan Yao , Qin Bo 
Published: December 2023

BackgroundGene therapy involves introducing and editing foreign genes in the body to treat and prevent genetic diseases. Adeno-associated virus (AAV) vector has become a widely used tool in gene therapy due to its high safety and transfection efficiency.MethodsThis study employs bibliometric analysis to explore the foundation and current state of AAV vector application in gene therapy research. A total of 6,069 publications from 1991 to 2022 were analyzed, retrieved from the Science Citation Index Expanded (SCI-E) within the Web of Science Core Collection (WoSCC) of Clarivate Analytics. Institutions, authors, journals, references, and keywords were analyzed and visualized by using VOSviewer and CiteSpace. The R language and Microsoft Excel 365 were used for statistical analyses.ResultsThe global literature on AAV vector and gene therapy exhibited consistent growth, with the United States leading in productivity, contributing 3,868 papers and obtaining the highest H-index. Noteworthy authors like Wilson JM, Samulski RJ, Hauswirth WW, and Mingozzi F were among the top 10 most productive and co-cited authors. The journal “Human Gene Therapy” published the most papers (n = 485) on AAV vector and gene therapy. Current research focuses on “gene editing,” “gene structure,” “CRISPR,” and “AAV gene therapy for specific hereditary diseases.”ConclusionThe application of AAV vector in gene therapy has shown continuous growth, fostering international cooperation among countries and institutions. The intersection of gene editing, gene structure, CRISPR, and AAV gene therapy for specific hereditary diseases and AAV vector represents a prominent and prioritized focus in contemporary gene therapy research. This study provides valuable insights into the trends and characteristics of AAV gene therapy research, facilitating further advancements in the field.
Optimal postoperative delirium prediction after coronary artery bypass grafting surgery: a prospective cohort study
Authors: Ma Ying , Sui Dongxin , Yang Shaozhong , Yang Xiaomei , Oldam Joseph , Semel Jessica L. , Wang Zhihao , Fang Ningning 
Published: December 2023

BackgroundPostoperative delirium (POD) presents as a serious neuropsychiatric syndrome in patients undergoing off-pump coronary artery bypass grafting (OPCABG) surgery. This is correlated with higher mortality, cognitive decline, and increased costs. The Age-adjusted Charlson Comorbidity Index (ACCI) is recognized as an independent predictor for mortality and survival rate. The purpose of our study is to estimate the predictive value of the ACCI on the POD in patients undergoing OPCABG surgery.MethodsThis prospective cohort study enrolled patients undergoing OPCABG surgery between December 2020 and May 2021 in Qilu Hospital. Patients were divided into the low-ACCI group (score, 0–3) and the high-ACCI group (score ≥4) according to their ACCI scores. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and CAM were used to diagnose POD within 7 days after surgery. The general, laboratory, and clinical data of the patients were recorded and collected. The characteristic ROC curve was applied to further assess the predictive value of the ACCI for POD in patients following OPCABG surgery.ResultsA total of 89 patients were enrolled, including 45 patients in the low-ACCI group and 44 patients in the high-ACCI group. The incidence of POD was higher in the high-ACCI group than in the low-ACCI group (45.5% vs. 15.6%, P = 0.003). Multivariate logistic regression analyses showed that the ACCI (OR, 2.433; 95% CI, 1.468–4.032; P = 0.001) was an independent risk factor for POD. The ACCI accurately predicted POD in patients following OPCABG surgery with an AUC of 0.738, and the Hosmer–Lemeshow goodness of fit test yielded X2 = 5.391 (P = 0.145).ConclusionThe high-ACCI group showed a high incidence of POD. The ACCI was an independent factor associated with POD in patients following OPCABG surgery. In addition, the ACCI could accurately predict POD in patients following OPCABG surgery.
Clinical Trial RegistrationClinicalTrials.gov, identifier CHiCTR2100052811.
The association of psychological stress with metabolic syndrome and its components: cross-sectional and bidirectional two-sample Mendelian randomization analyses
Authors: Li Cancan , Tao Tianqi , Tang Yanyan , Lu Huimin , Zhang Hongfeng , Li Huixin , Liu Xiuhua , Guan Weiping , Niu Yixuan 
Published: December 2023

BackgroundMetabolic syndrome (MetS) is a group of co-occurring conditions that increase the risk of cardiovascular disease, which include the conditions of hypertension, overweight or obesity, hyperglycemia, and dyslipidemia. Psychological stress is gradually being taken seriously, stemming from the imbalance between environmental demands and individual perceptions. However, the potential causal relationship between psychological stress and MetS remains unclear.MethodWe conducted cross-sectional and bidirectional Mendelian randomization (MR) analyses to clarify the potential causal relationship of psychological stress with MetS and its components. Multivariable logistic regression models were used to adjust for potential confounders in the cross-sectional study of the Chinese population, including 4,933 individuals (70.1% men; mean age, 46.13 ± 8.25). Stratified analyses of sexual characteristics were also performed. Bidirectional MR analyses were further carried out to verify causality based on summary-level genome-wide association studies in the European population, using the main analysis of the inverse variance-weighted method.ResultsWe found that higher psychological stress levels were cross-sectionally associated with an increased risk of hypertension in men (odds ratio (OR), 1.341; 95% confidence interval (CI), 1.023–1.758; p = 0.034); moreover, higher levels of hypertension were cross-sectionally associated with an increased risk of psychological stress in men and the total population (men: OR, 1.545 (95% CI, 1.113–2.145); p = 0.009; total population: OR, 1.327 (95% CI, 1.025–1.718); p = 0.032). Genetically predicted hypertension was causally associated with a higher risk of psychological stress in the inverse-variance weighted MR model (OR, 2.386 (95% CI, 1.209–4.710); p = 0.012). However, there was no association between psychological stress and MetS or the other three risk factors (overweight or obesity, hyperglycemia, and dyslipidemia) in cross-sectional and MR analyses.ConclusionAlthough we did not observe an association between psychological stress and MetS, we found associations between psychological stress and hypertension both in cross-sectional and MR studies, which may have implications for targeting hypertension-related factors in interventions to improve mental and metabolic health. Further study is needed to confirm our findings.
A reappraisal of transcriptional regulation by NR5A1 and beta-catenin in adrenocortical carcinoma
Authors: Lalli Enzo 
Published: December 2023

BackgroundOverexpression of the transcription factor NR5A1 and constitutive activation of canonical Wnt signalling leading to nuclear translocation of beta-catenin are hallmarks of malignancy in adrenocortical carcinoma (ACC). Based on the analysis of genomic profiles in H295R ACC cells, Mohan et al. (Cancer Res. 2023; 83: 2123-2141) recently suggested that a major determinant driving proliferation and differentiation in malignant ACC is the interaction of NR5A1 and beta-catenin on chromatin to regulate gene expression.MethodsI reanalyzed the same set of data generated by Mohan et al. and other published data of knockdown-validated NR5A1 and beta-catenin target genes,ResultsBeta-catenin is mainly found in association to canonical T cell factor/lymphoid enhancer factor (TCF/LEF) motifs in genomic DNA. NR5A1 and beta-catenin regulate distinct target gene sets in ACC cells.ConclusionOverall, my analysis suggests a model where NR5A1 overexpression and beta-catenin activation principally act independently, rather than functionally interacting, to drive ACC malignancy.