bluuebunny/crossref_metadata_2025_split huggingface dataset:
Avaliação da toxicidade e sensibilidade dérmica de uma formula-ção semi- sólida de óleo de linhaça (Linum usitatissimum L.)
Authors: Franco Eryvelton de Souza , Lima Larissa Caroline de Almeida Sousa , Bacelar Vera Kaissa Souza Santos , Silva Mirella Claudino Oliveira , Pereira Andreza da Silva , Torres Elaine da Silva , Maia Maria Bernadete de Sousa 
Published: January 2024

O objetivo deste trabalho foi avaliar a toxicidade dérmica de uma Formulação Semi-Sólida do Óleo de Linhaça (Linum usitatissimum L.) FSSOL (1%, 5%, 10% ou 50%) ou óleo de linhaça, utilizando os protocolos: 402 OECD para toxicidade aguda em camundongo Swiss (n=6); OECD 404 para irritação dermica em coelhos albinos (n=4); OECD 405 para irritação ocular em coelhos albinos (n=4) e OECD 406 para sensibilidade dermica em guinea pig (n=6), publicados pela Organization for Economic Co-operation and Development OECD e toxicidade dérmica sub-crônica em ratos Wistar (n=10) segundo o Guia para a realização de estudos de toxicidade pré-clínica de fitoterápicos da Agência Nacional de Vigilância Sanitária. Os resultados obtidos revelam que a FSSOL, nas concentrações e via administrada, não apresentaram toxicidade (dérmica e ocular) ou sensibilização dérmica, nos modelos animais utilizando.
Inserção de TDIC’s no currículo e sua utilização em sala de aula: uma relação entre desafios e impactos
Authors: Rogério Heudes Eduardo , Moreira Adna Caetano e Silva , De Carvalho Ianan Eugênia , Da Silva Júlio César Bezerra Vilar , De Castilho Luciane Pereira , Meroto Monique Bolonha das Neves , De Alencar Mychelle Silva , Da Silva Romézio Alves Carvalho 
Published: January 2024

O presente estudo é um conjunto de informações segmentadas e ordenadas no contexto para nortear o início do planejamento escolar para o uso das Tecnologias Digitais da Informação e Comunicação no processo de ensino e aprendizagem. Passando pelos componentes básicos de uma TDIC visando a situação mundial atual em seu uso e relacionando com o interesse da juventude no assunto em seu cotidiano. Explica também a sua inserção no currículo contando como uma adição de uma ferramenta no processo de ensino e aprendizagem respeitando a diversidade, a cultura e o âmbito social, político e econômico, destacando alguns desafios para a gestão das instituições em conseguir respeitar o currículo e também para o corpo docente no sentido ao incentivo à utilização de novas metodologias de ensino em salas de aula e seus impactos que a utilização de novas metodologias em que o aluno passa a ser ativo e o que isso pode refletir na sociedade, seja local ou regional.
Anesthesia for Craniotomy Tumor Removal Patient with Morbid Obesity
Authors: Bisri Dewi Yulianti , Maharani Mutivanya Inez , Bisri Tatang 
Published: January 2024

Purpose: Obesity is one of the greatest health challenges in the western world. Obesity is defined as a body mass index (BMI) >30 kg/m2, with BMI >35 and >55 kg/m2 considered ‘morbidly’ obese and ‘super morbidly’ obese, respectively. The aim of this study was to examine anesthetic management for craniotomy tumor removal in patients with morbid obesity.

Design/methodology/data analysis: This research uses a qualitative descriptive research method with a case study approach of a 39 year old female patient with a body weight of 110 kg, height 160 cm, and body mass index (BMI) 42.9 kg/m2, Mallampati score 2, thyromental distance > 3 fingers hospitalized for removal of meningioma. Data collection techniques in this research used literature study, observation and laboratory tests. The data that has been collected is then analyzed descriptively.

Findings: The results of the study showed that in the operating room, the patient was positioned in a neutral position 300 head up and Ramp. Preoxygenation with 100% O2 was performed via a face mask. Anesthesia was maintained with continuous intravenous propofol 25-50 μg/kg/min, intravenous rocuronium 40 mg/h, and volatile anesthesia using sevoflurane 0.5-1%vol with oxygen: air at a fraction of 50%. Monitoring during surgery includes evaluation of systolic blood pressure, diastolic blood pressure, mean arterial pressure, heart rate, oxygen saturation, ECG waves, EtCO2, and urine output. The operation lasted 4 hours in the supine position. Post-surgery patients are then treated in the Intensive Care Unit (ICU) for one day before being transferred to the ward and finally to a regular room. He received treatment for 5 days before being discharged. Problems faced during anesthesia in obese patients are airway management, ventilation, position, drug dosage, presence of comorbidities and post-operative care for recovery from anesthesia and surgery.

Originality/value: While addressing common challenges encountered during anesthesia in obese patients, this research takes a step further by proposing innovative solutions. The study acknowledges the complexities of airway management, ventilation, positioning, drug dosage, comorbidities, and post-operative care. However, it introduces novel considerations or techniques to mitigate these challenges, possibly involving emerging technologies or interdisciplinary collaboration for enhanced patient outcomes.

Practical implications: The practical implications of this research advocate for a nuanced and individualized approach to anesthetic management in morbidly obese patients undergoing craniotomy tumor removal, fostering improved patient care and safety.
The contribution of community-based libraries in climate action to strengthen the face of climate change supports the SDGs
Authors: Lusiana Elnovani , Yanto Andri , Nursari Tita , CMS Samson , Suryadi Dodih Firmansyah Suryadi 
Published: January 2024

Introduction: Climate change is one of the goals to be achieved in the Sustainable Development Goals (SDGs) which requires various groups to participate in adaptation and mitigation of global warming. This is because climate change causes various problems that have a direct impact on human life. The objectives of this research are to find out the role of libraries as a medium for climate change literacy and the role of libraries in climate action addressing climate change. Data Collection Methods: The research method used is literature study which is concerned with methods of collecting library data, reading and taking notes, and managing research materials from literary sources in the form of textbooks, journals, scientific articles, conducting studies by studying material obtained from literary sources in the form of articles. Results and Disccusion: The research results show that libraries can act as media that teach climate change literacy to the public. Libraries act as providers of information, libraries play a role in teaching environmental health literacy by educating the public to learn information about climate change. The library becomes an example of reduce and reuse behaviour by showing examples of how to reduce waste disposal emissions through actions to reduce the use of paper materials and the role in implementing go green. Conclusion: Community-based libraries contribute to climate action by becoming information providers, educators, given an examples and become role models.
การพัฒนาระบบบริหารจัดการสำนักงาน ตัวแทนประกันภัย หาง‍ดง‍-‍สะ‍เมิง (สี่แยกสะเมิง)
Authors: พละหงษ์ วิชา , สุวรรณศรี พิมพ์ชนก 
Published: January 2024

การพัฒนาระบบบริหารจัดการ สำนักงานตัวแทนประกันภัย หางดง – สะเมิง (สี่แยกสะเมิง) มีวัตถุประสงค์ 1) เพื่อพัฒนาโปรแกรมระบบบริหารจัดการสำนักงานตัวแทนประกันภัย หาง‍ดง‍-‍สะ‍เมิง (สี่แยกสะเมิง) 2) เพื่อศึกษาความพึงพอใจในการใช้งานระบบบริหารจัดการสำนักงานตัวแทนประกันภัย หาง‍ดง‍ - สะ‍เมิง (สี่แยกสะ‍เมิง) กลุ่มตัวอย่าง คือเจ้าของกิจการ จำนวน 1 คน และพนักงานประจำสำนักงาน จำนวน 2 คน เครื่องมือที่ใช้ในการพัฒนา ได้แก่ โปรแกรมระบบบริหารจัดการสำนักงานตัวแทนประกันภัย หาง‍ดง‍ - สะ‍เมิง (สี่แยกสะเมิง) และแบบสอบถามความพึงพอใจในประสิทธิภาพโปรแกรมระบบบริหารจัดการสำนักงานตัวแทนประกันภัย หาง‍ดง‍-‍สะ‍เมิง (สี่แยกสะเมิง) สถิติที่ใช้คือ ค่าเฉลี่ย และส่วนเบี่ยงเบนมาตรฐาน ผลการวิจัย พบว่า 1) ระบบมีการบริหารจัดการเก็บข้อมูลผู้เข้ารับบริการเป็นระเบียบ ง่ายต่อการสืบค้นเรียกใช้งาน ลดเวลาในการให้บริการ มีการคำนวณยอดรวมใบเสร็จรับเงินที่เที่ยงตรงรวดเร็ว แสดงสถานะบริการแก่ผู้เข้าใช้ บันทึกรายงานยอดการเข้ารับบริการย้อนหลัง แยกตามรายละเอียดยอดการขายทั้งต้นทุนและกำไร และนำผลที่ได้ไปประกอบการวิเคราะห์บริหารจัดการในสำนักงานได้ 2) ผลการประเมินความ พึงพอใจในการใช้งานของเจ้าของกิจการและพนักงาน พบว่าความพึงพอใจในประสิทธิภาพ ด้านสารสนเทศโดยรวมอยู่ในระดับมากที่สุด ด้านระบบโดยรวมอยู่ในระดับมาก และด้านประโยชน์ที่ได้รับ โดยรวมอยู่ในระดับมากที่สุด
Visualizing the target estimand in comparative effectiveness studies with multiple treatments
Authors: Simoneau Gabrielle , Mitroiu Marian , Debray Thomas PA , Wei Wei , Wijn Stan RW , Magalhães Joana Caldas , Bohn Justin , Shen Changyu , Pellegrini Fabio , Moor Carl de 
Published: January 2024

Aim:
Comparative effectiveness research using real-world data often involves pairwise propensity score matching to adjust for confounding bias. We show that corresponding treatment effect estimates may have limited external validity, and propose two visualization tools to clarify the target estimand.
Materials & methods:
We conduct a simulation study to demonstrate, with bivariate ellipses and joy plots, that differences in covariate distributions across treatment groups may affect the external validity of treatment effect estimates. We showcase how these visualization tools can facilitate the interpretation of target estimands in a case study comparing the effectiveness of teriflunomide (TERI), dimethyl fumarate (DMF) and natalizumab (NAT) on manual dexterity in patients with multiple sclerosis.
Results:
In the simulation study, estimates of the treatment effect greatly differed depending on the target population. For example, when comparing treatment B with C, the estimated treatment effect (and respective standard error) varied from -0.27 (0.03) to -0.37 (0.04) in the type of patients initially receiving treatment B and C, respectively. Visualization of the matched samples revealed that covariate distributions vary for each comparison and cannot be used to target one common treatment effect for the three treatment comparisons. In the case study, the bivariate distribution of age and disease duration varied across the population of patients receiving TERI, DMF or NAT. Although results suggest that DMF and NAT improve manual dexterity at 1 year compared with TERI, the effectiveness of DMF versus NAT differs depending on which target estimand is used.
Conclusion:
Visualization tools may help to clarify the target population in comparative effectiveness studies and resolve ambiguity about the interpretation of estimated treatment effects.
BRAND MANAGEMENT ON THE EXAMPLE OF “ADIDAS AG“
Authors: Radaković Milan , Turčinović Željko , Gavrilović Ana 
Published: January 2024

Adidas is considered one of the most famous and successful sports brands, which strives for constant development and progress, which is shown by frequent innovations and new models, but also by very original advertising campaigns. In today's business, the brand has become the need of every company, and in the life of every consumer, over time, it has become an indispensable factor.
Adidas has recognized the importance of the brand in modern business, and thanks to this, it will definitely achieve a long-term competitive advantage on the market and be in the leading positions of its markets.
DIGITAL TRANSFORMATION IN THE SPORTS INDUSTRY
Authors: Dašić Goran 
Published: January 2024

There is no doubt that innovative technologies and their adequate application are the driving force behind the development of various economic and business sectors. Today, digitization, i.e., digital transformation, represents key global trends in the world economy, the process of transformation of society and the economy, but also a prerequisite for the survival, growth, and development of companies in the domestic and global market. Digital transformation is the process of integrating digital technologies into all areas of business, which implies radical changes in the way technology, people and business processes are used. It is a continuous process that has no destination.
For digital natives, the digital environment represents a natural environment. However, for traditional systems, the adoption and application of digital technologies is a complex job that not only changes the internal functioning of the organization, but also the user experience. The sports industry is going through rapid changes, and in this it is not significantly different from other industries, and digital technology provides unprecedented opportunities for growth. Digitization in sport implies the implementation of digital technology in all respects. In this regard, the paper will analyze digital transformations from the perspective of both organizers and spectators of sporting events.
Pengaruh Penggunaan Media Sosial Sebagai Media Promosi Kesehatan Terhadap Tingkat Pengetahuan Kesehatan Reproduksi Remaja Di SMPN 1 Sakra
Authors: Herli Masturi  , Husniyati Sajalia  , R Supini  
Published: January 2024

Ditengah kemajuan teknologi dan perubahan sosial, pola pendidikan orang tua kepada remaja tidak berubah. Informasi tentang kesehatan reproduksi dan seksualitas masih tabu untuk dibicarakan. Akibatnya, remaja mendapatkan informasi yang salah, sehingga terjadi banyaknya penyimpangan perilaku seksual para remaja. Penelitian ini merupakan penelitian pre-experiment design dengan pendekatan one group pretest posttest design, populasi sebesar 782 orang, sampel sebesar 89 orang yang diambil menggunakan Stratified random sampling, instrument yang digunakan adalah kuesioner. Analisa data menggunakan Uji Paired T-Test. Hasil Uji Paired T-Test menunjukkan nilai signifikansi pengetahuan sebelum dan sesudah diberikan promosi kesehatan sebesar 0,000 < 0,05. yang berarti Hɑ diterima dan Ho ditolak. Kesimpulan dari penelitian ini adalah ada pengaruh penggunaan media sosial sebagai media promosi kesehatan terhadap tingkat pengetahuan kesehatan reproduksi remaja di SMPN 1 Sakra.
Pre-Service Teacher Competence in a Teacher Education Institution
Authors: Rubio Jennifer , Saenz Consuelo 
Published: January 2024

This study aimed to describe the level of competence of pre-service teachers of Camarines Norte State College College of Education in terms of the Philippine Professional Standards for Teachers (PPST) and the significant relationship between their academic performance and level of competence. The study employed the descriptive-correlational research design. Data used in this study came from a survey of BSEd and BEEd pre-service teachers (n=125) and cooperating teachers (n=125) in Camarines Norte, Philippines. A questionnaire consisting of the specific indicators of the PPST was the main data-gathering instrument. The study revealed that the pre-service teachers had an advanced level of competence in Content Knowledge and Pedagogy, Learning Environment, Curriculum and Planning, Community Linkages and Professional Engagement, Personal Growth and Professional Development, and above average level of competence along Diversity of Learners and Assessment and Reporting domains of the PPST. Policies and programs were proposed to improve the level of competence of the pre-service teachers.
A Terapia da Família Adotiva
Authors: Ladvocat Cynthia 
Published: January 2024

Um dos grandes mitos na adoção destaca a representação psíquica das imagos parentais biológicas e adotivas. A autora apresenta o relato do caso de uma menina atendida dos seis aos oito anos e que retorna ao processo terapêutico na adolescência. O trabalho com o Genograma levanta a análise da biografia, incluindo o abandono da mãe biológica, o processo de adoção, da revelação, o contato da adolescente com suas origens e sua maternidade na vida adulta.
Kesantunan Bahasa di Kampus STKIP PGRI Sidoarjo
Authors: Hikmah Amimah , Sari Lela , Khasanah Mufidatul , Fikri Mohammad , Rismayanti Trinita , Nurhayati Eni 
Published: January 2024

Penelitian ini bertujuan untu mendeskripsikan kesantunan berbahsa pada mahasiswa STKIP PGRI Sidoarjo. Dalam penelitian ini menggunakan pendekatan kualitatif dengan metode deskriptif. Sebagian dari mahasiswa minim kesadaran dalam hal kesantunan berbahasa. Dari penelitan ini, peneliti beharap agar mahasiswa STKIP PGRI Sidorjo selalu menggunakan bahasa yang santun dalam berkomunikasi diantara sesamanya dalam kehidupan sehari-hari. Teknik yang digunakan dalam pengumpulan data yakni tekni simak bebas libat cakap, teknik rekaman, dan teknik catat. Sasaran untuk mengetahui penyimpangan prinsip kesantunan berbahasa dalam kegiatan belajar dalam pilihan kata dan cara berbicara yang santun anatara dosen dan mahasiswa.
Kata kunci: Kesantunan Berbahasa; Mahasiswa STKIP PGRI Sidoarjo.
FEATURES OF STATE SUPERVISION IN THE FIELD OF CIVIL DEFENSE DURING THE YEARS OF RESTRICTIONS ON INSPECTIONS
Authors: Chernousov Ilya , Timasheva Elena , Kuzmina Tatyana 
Published: January 2024

Changes in regulatory legal acts of the Russian Federation regulating control and supervisory activities are considered. Organizational issues touched upon and conducting inspections of local governments under restrictions and prohibitions on supervision. A step-by-step procedure for the actions of officials of the supervisory authority is proposed when initiating and coordinating unscheduled inspections of the activities of the executive and administrative body of the municipality. Examples are given of disclosing the characteristics of violations that entail an immediate threat of harm to life and the health
of citizens, national defense and state security. The problem is identified, which consists in the ambiguity of the interpretation of some provisions of regulatory legal acts. Issues have been identified that require resolution or additional clarification from the legislative bodies.
O PROCESSO DE REGIONALIZAÇÃO NO PROGRAMA DE REGIONALIZAÇÃO DO TURISMO: UMA DISCUSSÃO CRÍTICA
Authors: Sousa Diogo , Araújo Sobrinho Fernando Luiz 
Published: January 2024

O Programa de Regionalização do Turismo teve, como premissa, a abordagem territorial de sua implementação. Ela se daria a partir da geograficização do turismo em regiões, dado a partir de um processo de produção do espaço regional. Porém, mo limiar do ano de 2024, após duas décadas de implementação, é visível que a regionalização do turismo foi executada de modo que o território ficou, na realidade, reduzido a um conceito, sendo tratado somente como “palco”, contrariando a própria premissa da política pública. Este trabalho irá analisar, a partir do entendimento da diferenciação de territórios, e demais dados referenciais bibliográficos e documentais, essa abordagem dentro da regionalização, a partir da ótica crítica, ao afirmar que o Programa de Regionalização do Turismo não regionalizou e, portanto, criou regiões turísticas a partir de uma conceituação meramente mercadológica.
Mobile Learning and Life-long Learning: Nurturing Higher Education Students' Learning in the Face of Uncertainty
Authors: Sabri Shima , Shuib Liyana , Murad Roslinda 
Published: January 2024

Since the beginning of the COVID-19 disease in late 2019, a majority of the learners from Higher Education Institutions (HEI) have resorted to blended and distance learning. There has been extensive discussion concerning distance learning; however, the aspects that motivate learners to use mobile phones for learning are yet to be explored comprehensively. This paper identifies the aspects that could potentially motivate learners to start using mobile devices for learning, which is referred to as mobile learning (m-Learning); it motivates the learners to participate in studies. Such is the case because a majority of the learners need to find time to focus on studies. This is especially significant for remote studying because it brings several challenges like domestic work and work-life balance that need to be ensured along with studies. Furthermore, learners may miss online classes due to lack of stable connectivity. This is where m-Learning has its advantages since it is independent of place and time. With the intent to provide HEI learners with an appropriate learning environment, this paper comprises a review of previous research concerning m-Learning design. It is understood that the situation and age of an HEI learner should be the basis for determining the andragogical factors. It is suggested that future research in this domain focus on assessing the factors that promote m-Learning among HEI learners so that these individuals can continue education despite having physical distance from their peers.
Perbanyakan Spesies Phalaenopsis amabilis L Melalui Induksi Protocorm Like Bodies (PLB) Sekunder
Authors: Hidayah Ummu Fitrothul , Yudha Yoshua S , Widyajayantie Dwi , Apriliani Elisa 
Published: January 2024

Secara umum perbanyakan anggrek secara in vitro dilakukan dengan menggunakan protocorm like bodies (plb). Faktor terpenting dalam kultur jaringan salah satunya adalah penggunaan media kultur yang responsif bagi pertumbuhan eksplan. Pengembangan protokol produksi membutuhkan penelitian terkait media yang sesuai untuk memperbanyak tanaman. Penelitian bertujuan untuk mempelajari formulasi media yang sesuai untuk multiplikasi plb anggrek Phalaenopsis amabilis, serta mengetahui respon pertumbuhan dan perkembangan plb Phalaenopsis amabilis pada tiga media yang berbeda. Penelitian menggukan Rancangan Acak Lengkap (RAL) dengan faktor jenis media (Murashige and Skoog, Kudson C, dan Schenk dan Hildebrant) dengan penambahan zat pengatur tumbuh (1 mg L-1 BA + 0.5 mg L-1 NAA + 1 mg L-1 CaP + 0.1 mg L-1 arang aktif + gula 30 g L-1). Hasil penelitian menunjukkan bahwa perlakuan terbaik dalam menumbuhkan tunas pada eksplan plb terdapat pada media Schenk dan Hildebrant (SH) dengan nilai rata rata sebesar 6,30. Sedangkan waktu pembetukan plb sekunder tercepat terlihat pada penggunaan media Knudson C (KC) pada minggu ke-3 setelah kultur.
Pengaruh Risk Based Capital, Premi Neto, Dan Likuiditas Terhadap Profitabilitas Perusahaan Asuransi Jiwa The Effect of Risk Based Capital, Net Premium, And Liquidity On The Profitability Of Life Insurance
Authors: Stevani Sarah 
Published: January 2024

Penelitian ini bertujuan untuk mengetahui apakah tingkat Return on Asset pada perusahaan asuransi jiwa akan meningkat jika perusahaan memiliki Risk Based Capital, Premi Neto, dan Liabilitas dalam jumlah yang besar. Sampel be rjumlah 28 dengan total 50 data selama 3 tahun penelitian yang berasal dari asuransi jiwa yang terdaftar pada Otoritas Jasa Keuangan. Metode analisis menggunakan metode deskriptif dengan pendekatan kuantitatif. Hasil penelitian menunjukan ba hwa Risk Based Capital berpengaruh terhadap Profitabilitas hal ini dapat dilihat dari uji T - test , yaitu Ha < 0,005 dan hasil yang telah dilakukan menunjukan angka sig. 0,000< 0,05. Hasil penelitian Premi neto menunjukan tidak berpengaruh terhadap Profitabilitas hal ini dapat dilihat dari uji T-test , yaitu Ha < 0,005 dan hasil yang telahdilakukan menunjukan angka sig. 0,429 < 0,05. Hasil penelitian Likuiditas menu njukan tidak berpengaruh terhadap Profitabilitas hal ini dilihat dari uji T-test , yaitu Ha < 0,05 dan hasil yang telah dilakukan menunjukan angka sig. 0,435 < 0,05. Hasil penelitian ini menunjukan bahwa Risk Based Capital, Premi Neto, Dan Likuiditas secara simultan berpengaruh terhadap Profitabilitas hal ini dapat dilihat dari hasil F-test nilai signifikansi sebesar 0,001 < 0,05