bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of antimicrobial resistance on sustainable development goals and the integrated strategies for meeting environmental and socio‐economic targets
Authors: Bhattacharya Riya , Bose Debajyoti , Gulia Khushabu , Jaiswal Apurva 
Published: November 2023

AbstractThe pattern in mortality and morbidity associated with infectious diseases can be linked to different variables. However, advancements in sanitation and public health, as well as the development of vaccines and antibiotics are among the most relevant of these factors. The emergence of antimicrobial resistance is a natural and unavoidable result of evolutionary adaptation of pathogenic microbes and their exposure to these chemical agents. The widespread use of these medications has substantially accelerated up this process. This review investigates the mechanism through which sustainable development goals are impacted by AMR. It also examines methods through which the issue might be better integrated into the policy‐making frameworks of international organizations. The necessity of effective antibiotics during the treatment of infections and medical care is evaluated with an analysis on AMR influencing the ecological, societal, and economic interests that are outlined in the framework for the SDGs. Emphasis is on the necessity for strengthening the scientific community through international collaboration and accountability of distribution especially after the COVID‐19 pandemic. This offers initiatives toward a deeper participation of low and middle‐income countries with high income countries to create channels for national and local governance for executing policies combatting AMR.
A review on solar thermal energy storage systems using phase‐change materials
Authors: Ram Satyendra , Prasad A. K. , Hansdah Dulari 
Published: November 2023

AbstractThis paper presents a review of the storage of solar thermal energy with phase‐change materials to minimize the gap between thermal energy supply and demand. Various types of systems are used to store solar thermal energy using phase‐change materials. The performance of latent heat storage is dependent on the shape and size of the fins, the orientation and design of the storage unit, and its position. The efficiency of a solar thermal collector integrated with phase change material depends on the inclination of the collector, the position of the phase change material, and its thermo‐physical properties. The study of the thermo‐physical properties of various phase‐change materials and their effects is the focus of this paper.
Strawberry Protease as a Laundry Detergent Additive Candidate: Immobilization, Compatibility Study with Detergent Ingredients, and Washing Performance Test
Authors: Alici Esma Hande , Arabaci Gulnur 
Published: November 2023

AbstractThe potential of strawberry‐derived protease as a component of laundry detergent is investigated. The compatibility of the enzyme with various surfactants, oxidizing agents, and commercial detergents is tested. The immobilized enzyme prepared by immobilizing Co2+ ions together with the enzyme is also tested. Strawberry crude protease shows high stability in the presence of surfactants frequently used in detergents. The enzyme is found to be relatively stable to oxidizing agents. In addition, it is determined that strawberry protease works in excellent compatibility with different commercial solid and liquid detergents in the Turkish market and also maintains its stability very well. Washing tests based on visual examination also reveal that the enzyme improves the washing performance of the tested detergent. All these properties and high activity at alkaline pH make this enzyme a very strong candidate for use in laundry detergent formulations.
Vereinfachter zyklischer Scherversuch zum PWD‐Aufbau in grobkörnigen Böden
Authors: Bacic Bozana , Herle Ivo 
Published: November 2023

AbstractDer Aufbau des Porenwasserdrucks (PWD) während einer Scherbeanspruchung bei behinderter Drainage findet besonders ausgeprägt in lockeren, gesättigten, grobkörnigen Böden statt und führt zur Verringerung der effektiven Spannungen und der Bodensteifigkeit. Unter Berücksichtigung einer vergleichbaren Bodenstruktur (Korngerüst) und unter gleichen Versuchsbedingungen (Spannungsniveau, Wegamplitude usw.) wird das Verhalten verschiedener Böden bei einer gleichen äußeren Belastung unterschiedlich sein. Hierzu wird ein vereinfachter zyklischer Scherversuch (PWD‐Tester) vorgestellt, der einen Vergleich der Neigung zum Aufbau des PWDs gegenüber der Variation von Anfangsdichten für verschiedene Sande ermöglicht. Der Versuch setzt sich aus einem Probeneinbau, einer Konsolidation und einer anschließenden zyklischen Scherung der Probe bei undrainierten Bedingungen innerhalb kurzer Zeit (ca. 30 Minuten) zusammen. Das Ziel dieses Verfahrens ist es, jedem getesteten Sand einen Indexwert zuzuordnen und somit die Neigung verschiedener Sande zum PWD‐Aufbau bis zur Bodenverflüssigung unter behinderter Drainage in Abhängigkeit der Einbaudichte zu quantifizieren.
Recognition and interpretation of aggressive driving behavior for heavy‐duty vehicles based on artificial neural network and SHAP
Authors: Cheng Chuangang , Chen Shuyan , Ma Yongfeng , Khattak Aemal J. , Zhang Ziyu 
Published: November 2023

AbstractAggressive driving significantly impacts traffic safety, and heavy‐duty vehicle drivers are more liable for causing serious crashes. This paper analyzes drivers' aggressive driving behavior from the vehicle type perspective and identifies the influencing factors of aggressive driving behavior through artificial neural network (ANN) and Shapley additive explanations (SHAPs). Using Kaggle's open‐source aggressive driving data, we establish an ANN model to identify driving styles, where road conditions, environmental conditions, and vehicle parameters are independent variables and driving style is a dependent variable. The following measurements, including accuracy, recall, precision, and F1 score, are used to evaluate the model's performance, and the neural network got 85.33%, 82.32%, 84.16%, and 0.8308, respectively. To illustrate the influence of independent variables, the SHAP algorithm is used to analyze the model's feature importance. It was found that illumination and weather conditions influenced the model's performance along with the vehicle length. The number of lanes relates to driving style, and there were more aggressive driving behaviors on two‐lane roads than on single‐lane roads. Besides, heavy‐duty vehicle drivers were more likely to drive aggressively in wet road conditions and indulge in aggressive driving behaviors at night. Particularly, drivers of heavy‐duty vehicles were more likely to drive aggressively, provided that the vehicle in front was also a heavy‐duty vehicle. These findings inform heavy‐duty vehicle drivers to reduce aggressive driving behavior. The information is suitable for inclusion in driver education programs, thus improving traffic safety.
Drivers of healthcare expenditure growth in West Africa: A panel data investigation
Authors: Dauda Rasaki Stephen , Balogun Fiyinfoluwa Adeyinka 
Published: November 2023

AbstractPer capita health expenditure in West African countries appears to have assumed a growing trend over the years. This may not be unconnected with the critical role played by health in economic growth, sustainable development and human capital formation. This study analysed drivers of healthcare expenditure in West Africa, using panel data analysis. Random Effects estimating technique was preferred to pooled Ordinary Least Squares and Fixed Effects techniques based on Hausman and Breusch‐Pagan Lagrangian multiplier tests. Data employed were sourced from World Bank's world development indicators. The findings indicated that number of people using at least basic sanitation services, incidence of tuberculosis, malaria incidence, and per capita GDP, significantly increased healthcare expenditure in West Africa within the study period. Infant and under‐five mortality (UFM) rates raised healthcare expenditure but insignificantly in the sub‐region. The study recommends the need to reduce malaria and tuberculosis incidences as well as UFM rate in West Africa through appropriate policy enactment. Such policies should include adequate investment in education, increased per capita income, development of malaria vaccines, maintenance of hygienic environment and free treatment of tuberculosis patients.
cisDynet: An integrated platform for modeling gene‐regulatory dynamics and networks
Authors: Zhu Tao , Zhou Xinkai , You Yuxin , Wang Lin , He Zhaohui , Chen Dijun 
Published: November 2023

AbstractChromatin accessibility sequencing has been widely used for uncovering genetic regulatory mechanisms and inferring gene regulatory networks. However, effectively integrating large‐scale chromatin accessibility datasets has posed a significant challenge. This is due to the lack of a comprehensive end‐to‐end solution, as many existing tools primarily emphasize data preprocessing and overlook downstream analyses. To bridge this gap, we have introduced cisDynet, a holistic solution that combines streamlined data preprocessing using Snakemake and R functions with advanced downstream analysis capabilities. cisDynet excels in conventional data analyses, encompassing peak statistics, peak annotation, differential analysis, motif enrichment analysis, and more. Additionally, it allows to perform sophisticated data exploration, such as tissue‐specific peak identification, time course data modeling, integration of RNA‐seq data to establish peak‐to‐gene associations, constructing regulatory networks, and conducting enrichment analysis of genome‐wide association study (GWAS) variants. As a proof of concept, we applied cisDynet to reanalyze comprehensive ATAC‐seq datasets across various tissues from the Encyclopedia of DNA Elements (ENCODE) project. The analysis successfully delineated tissue‐specific open chromatin regions (OCRs), established connections between OCRs and target genes, and effectively linked these discoveries with 1861 GWAS variants. Furthermore, cisDynet was instrumental in dissecting the time course open chromatin data of mouse embryonic development, revealing the dynamic behavior of OCRs over developmental stages and identifying key transcription factors governing differentiation trajectories. In summary, cisDynet offers researchers a user‐friendly solution that minimizes the need for extensive coding, ensures the reproducibility of results, and greatly simplifies the exploration of epigenomic data.
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Authors: Ji Jianlong , Wang Zhenxing , Zhang Fan , Wang Bin , Niu Yan , Jiang Xiaoning , Qiao Zeng‐ying , Ren Tian‐ling , Zhang Wendong , Sang Shengbo , Cheng Zhengdong , Sun Qijun 
Published: November 2023

AbstractA pulse‐driven electrochemical synaptic transistor for supersensitive and ultrafast biosensor is proposed.
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Authors: Li Hanxi , Hu Jiayang , Chen Anzhe , Zhang Yishu , Wang Chenhao , Wang Beiduo , Tong Yi , Zhou Jiachao , Loh Kian Ping , Xu Yang , Hasan Tawfique , Yu Bin 
Published: November 2023

AbstractThe cover image focuses on neuronal circuit motif with specialized excitatory–inhibitory connectivity pattern. The neuronal circuit is an advanced functional unit of the brain beyond neurons and synapses. Neurons do not function in isolation and are linked to ensembles or circuit motifs that process specific types of information, enables multidimensional signal processing in the information flow of the brain. The authors demonstrate a core processor that can be employed to construct commonly used neuronal circuits and further perform bio‐realistic neuromorphic computing. Exploring the working principle, physical configuration, scalable design, and extensive signal‐processing capabilities of core processing neuron is crucial for advancing hardware development for brain‐inspired integrated neuromorphic systems.
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“Emotions are what will draw people in”: A study of critical affective literacy through digital storytelling
Authors: Jiang Jialei 
Published: November 2023

AbstractThis study explores the implications of critical affective literacy through digital storytelling projects produced by first‐year college writing students. The goal was to examine college students' affective and emotional responses to social justice issues, such as racial profiling, educational inequality, and animal protection, through the lens of digital storytelling. Pairing multimodal pedagogy with critical affective literacy, this study was carried out in two first‐year writing courses in the United States. The researcher who conducted this study also taught the class sessions. Employing the methodology of a qualitative case study, the author gathered information through conducting semi‐structured interviews with 11 students, observing the students' multimodal composition processes, and reviewing the students' digital storytelling videos. The analysis of the data showed that the participants performed critical emotional action when creating digital stories to draw the public's attention to social justice issues. This paper recommends that educators incorporate digital storytelling into social justice pedagogy and cultivate learners' critical affective literacy.
Adolescents' motivation to use social network sites from a psychological needs perspective
Authors: Wong Shu Ling , McLellan Ros 
Published: November 2023

AbstractIntroductionAdolescents' social network sites (SNS) use is prominent during the developmental period. Various adolescents' motivations for using SNS have been reported. However, there is a lack of psychological perspectives in understanding the reasons for adolescents to use SNS. This study explored adolescents' motivation to use SNS, and a comprehensive psychological framework was used to dismantle adolescents' reasons and purposes for using SNS. Adolescents' ways of using SNS were explored to contextualize teens' SNS use.MethodsSemistructured interviews with 18 Malaysian adolescents (Mage = 15; 50% female; 10 Malay, 5 Chinese, 1 Indian, 1 Other Bumiputera) were conducted. The qualitative data were collected in 2021 in Malaysia through online video calls. Reflexive thematic analysis was the analytic approach.ResultsSix motivations for using SNS were identified: social interaction, content subscription and exploration, emotional support, participation, distraction, and self‐expression. Each of the motivations was explicitly linked with different psychological needs. Adolescents were found to use SNS differently in three aspects: deliberate use (i.e., on purpose of use and time spent on SNS), content‐selective, and audience‐selective.ConclusionThis study demonstrates that psychological needs are the psychological reasons for adolescents' motivations for using SNS. Adolescence developmental tasks like strong peer identification and identity explorations are parts of the basic and compound psychological needs. Teens are pursuing a sense of self‐coherence by using SNS. Adolescents demonstrated to use SNS differently at being deliberate and selective, which is speculated to be a result of the conflict between reflexive and reflective thought processes during SNS use.
Epidermis of Cereus hildmannianus as a biomimetic scaffold for tissue engineering
Authors: Reddy Narendra , Reddy Roopa , Guna Vijaykumar , Nagananda G. S. , Aramwit Pornanong 
Published: November 2023

AbstractA thin plastic‐like film separated from the epidermis of Cereus hildmannianus has excellent tensile strength, resistance to water and high antimicrobial activity and supports the growth of mouse fibroblast cells. Cactuses are one of the most under explored plant species with high potential for food, materials, pharmaceutical and other applications. Although studies have shown the ability of cactuses to be used for food, as a source for fibers, as reinforcement for composites and other applications, the role of individual layers and their properties has been studied to a limited extent. In this paper, a thin translucent layer was separated from the epidermis of C. hildmannianus and studied for its composition, structure and properties. The layer is composed of about 73% cellulose and 2% lignin and morphologically, shows surface with uneven and serrated edges. Films with length of up to 36 cm, strength of 6.8 MPa and elongation of 2.5% could be peeled from the cactus suggesting their suitability for food packaging and other applications. X‐ray diffraction patterns and FTIR spectrums indicated that the films are similar to that of cellulose and major thermal degradation occurred above 280°C. Compared to standards, the cactus films showed about 41% and 44% inhibition against gram positive and gram negative bacteria and 67% inhibition of the common fungal strain (A. niger). Films showed high stability in water and to common chemicals. When used as substrates for mouse fibroblast cell growth, no cytotoxicity was observed and the cactus peel supported the attachment and proliferation of cells demonstrating potential to be used as a biomaterial for tissue engineering applications.
Incidence‐free sets and edge domination in incidence graphs
Authors: Spiro Sam , Adriaensen Sam , Mattheus Sam 
Published: November 2023

AbstractA set of edges of a graph is an edge dominating set if every edge of intersects at least one edge of , and the edge domination number is the smallest size of an edge dominating set. Expanding on work of Laskar and Wallis, we study for graphs which are the incidence graph of some incidence structure , with an emphasis on the case when is a symmetric design. In particular, we show in this latter case that determining is equivalent to determining the largest size of certain incidence‐free sets of . Throughout, we employ a variety of combinatorial, probabilistic and geometric techniques, supplemented with tools from spectral graph theory.
Individualized threshold of the involuntary weight loss in prognostic assessment of cancer
Authors: Xie Hailun , Zhang Heyang , Ruan Guotian , Wei Lishuang , Ge Yizhong , Lin Shiqi , Song Mengmeng , Wang Ziwen , Liu Chenan , Shi Jinyu , Liu Xiaoyue , Yang Ming , Zheng Xin , Chen Yue , Zhang Xiaowei , Shi Hanping 
Published: November 2023

AbstractBackgroundInvoluntary weight loss (WL) is a common symptom in cancer patients and is associated with poor outcomes. However, there is no standardized definition of WL, and it is unclear what magnitude of weight loss should be considered significant for prognostic purposes. This study aimed to determine an individualized threshold for WL that can be used for prognostic assessment in cancer patients.MethodsUnivariate and multivariate analyses of overall survival (OS) were performed using Cox proportional hazard models. The Kaplan–Meier method was performed to estimate the survival distribution of different WL levels. Logistic regression analysis was used to determine the relationship between WL and 90‐day outcomes. Restricted cubic splines with three knots were used to examine the effects of WL on survival under different body mass index (BMI) conditions.ResultsAmong the 8806 enrolled patients with cancer, median survival time declined as WL increased, from 25.1 to 20.1, 17.8 and 16.4 months at <2%, 2–5%, 5–10% and ≥10% WL, respectively (P < 0.001). Multivariate adjusted Cox regression analysis showed that the risk of adverse prognosis increased by 18.1% based on the SD of WL (5.45 U) (HR: 1.181, 95% CI: 1.144–1.219, P < 0.001). Similarly, categorical WL was independently associated with OS in patients with cancer. With the worsening of WL, the risk of a poor prognosis in patients increases stepwise. Compared with <2% WL, all‐cause mortalities were 15.1%, 37% and 64.2% higher in 2–5%, 5–10%, and ≥10% WL, respectively. WL can effectively stratify the prognosis of both overall and site‐specific cancers. The clinical prognostic thresholds for WL based on different BMI levels were 4.21% (underweight), 5.03% (normal), 6.33% (overweight), and 7.60% (obese). Multivariate logistic regression analysis showed that WL was independently associated with 90‐day outcomes in patients with cancer. Compared with patients with <2% WL, those with ≥10% WL had more than twice the risk of 90‐day outcomes (OR: 3.277, 95% CI: 2.287–4.694, P < 0.001). Systemic inflammation was a cause of WL deterioration. WL mediates 6.3–10.3% of the overall association between systemic inflammation and poor prognoses in patients with cancer.ConclusionsAn individualized threshold for WL based on baseline BMI can be used for prognostic assessment in cancer patients. WL and BMI should be evaluated simultaneously in treatment decision‐making, nutritional intervention, and prognosis discussions of patients with cancer.
Correlations between vegetative autonomic function and specific left atrial functions in healthy adults: Insights from the three‐dimensional speckle‐tracking echocardiographic MAGYAR‐Healthy Study
Authors: Nemes Attila , Kormányos Árpád , Orosz Andrea , Ambrus Nóra , Várkonyi Tamás T. , Lengyel Csaba 
Published: November 2023

AbstractIntroductionThe functioning of the left atrium (LA) is partly controlled by the neural system. It was purposed to evaluate correlations between the result of Ewing's 5 standard cardiovascular reflex tests (SCRTs) characterizing autonomic function and LA volumetric and functional features as assessed by three‐dimensional speckle‐tracking echocardiography (3DSTE) in healthy individuals.Materials and MethodsThe current study comprised 18 healthy volunteers being in sinus rhythm (mean age: 35 ± 12 years, 10 men). Measurement of blood pressure, ECG, 5 SCRTs, two‐dimensional Doppler echocardiography and 3DSTE were performed. These parameters were in normal ranges in all cases.ResultsFrom LA volumetric parameters, only systolic total atrial emptying fraction (r = 0.559, p = 0.037) and early diastolic passive atrial emptying fraction (r = 0.539, p = 0.047) correlated with systolic blood pressure response to standing representing sympathetic autonomic function. From LA strains, peak mean segmental LA radial strain (RS) (r = −0.532, p = 0.050), global and mean segmental LA circumferential strain (CS) (r = 0.662, p = 0.010 and r = 0.635, p = 0.015, respectively) representing systolic LA function correlated with Valsalva ratio representing parasympathetic autonomic function. Global LA‐RS (r = −0.713, p = 0.040) and LA‐CS (r = 0.657, p = 0.011) and mean segmental LA‐CS (r = 0.723, p = 0.003) at atrial contraction representing end‐diastolic atrial contraction showed correlations with Valsalva ratio, as well. Peak global and mean segmental LA‐CS (r = 0.532, p = 0.050 and r = 0.530, p = 0.050) and the same strains at atrial contraction (r = 0.704, p = 0.005 and r = 0.690, p = 0.006) representing systolic function and end‐diastolic atrial contraction correlated with systolic blood pressure response to standing representing both parasympathetic and sympathetic autonomic functions.ConclusionsSignificant correlations between features of vegetative autonomic function represented by Ewing's 5 SCRTs and specific LA functions represented by 3DSTE‐derived LA volume‐based functional properties and strains could be demonstrated in healthy adults.