bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of knee cartilage biomechanics in finite element analysis using inputs from AnyBody and OpenSim
Authors: Peitola Joose P. J. , Esrafilian Amir , Eskelinen Atte S. A. , Andersen Michael S. , Korhonen Rami K. 
Published: October 2023

Abstract
Musculoskeletal (MS) modeling is an effective technique for examining body- and joint-level motion and loading. In knee joint models, the obtained joint kinematics and kinetics from the MS analysis are often used as inputs to finite element (FE) analysis to produce estimates for tissue-level responses. Previous research has explored how body- and joint-level estimates might be altered when using different MS modeling software, but there is a lack of information about the possible effects on tissue-level analysis. The aim of this study was to compare the cartilage tissue-level mechanics in subject-specific FE models with kinematic and kinetic inputs obtained from two widely used models, one applied in AnyBody and one in OpenSim. Motion data from gait trials of two healthy subjects were used with two commonly utilized MS models, one from each MS software. The obtained MS estimates were then used as inputs to the FE analysis, which was implemented in ABAQUS. Although the resulting cartilage mechanics were mostly comparable, the AnyBody- driven FE model estimated slightly higher maximum principal stresses in the medial cartilage for both subjects. The OpenSim-driven FE model estimated more anterior and lateral center of pressure in the lateral tibial cartilage, and more posterior in the medial tibial cartilage. Understanding and acknowledging these differences due to changes in the modeling environment is important to ensure reliable and accurate analysis of tissue-level knee mechanics, e.g., when predicting knee osteoarthritis progression and the effects of rehabilitations.
Relationship between interlaminar angle and the superior articular process removal range in patients with lumbar disc herniation during Percutaneous Endoscopic Interlaminar Discectomy: a cross-sectional study
Authors: Kong Xiangzhen , Wang Zihao , Zhu Xuetao , Zhang Yuanqiang , Wei Jianlu , Wei Zhijian , Cheng Lei 
Published: October 2023

Abstract
Objective:
Explore the relationship between the superior articular process removal range (SAPR) during Percutaneous Endoscopic Interlaminar Discectomy （PEID）and the interlaminar angle (ILA). In addition, we assessed the relationship between other imaging parameters and surgical difficulty.
Methods:
Collect the data of 237 patients who underwent PEID at Qilu Hospital of Shandong University. Measure the imaging data, such as ILA, facet angle (FA), facet joint medial distance (FMD), and the SAPR, and compare their statistical difference.
Results:
SAPR is negatively related to ILA(P<0.05). For patients with the L4/L5 segment operation, the average SAPR is 6.15±3.02mm. The SAPR of the patients with surgical segment ILA of 47.50-72.52° was 9.06±1.70mm. That of the patients with surgical segment ILA of 72.71-86.06° was 7.30±1.22mm. That of the patients with surgical segment ILA of 86.31-96.37° was 6.50±1.48mm. That of the patients with surgical segment ILA of 97.10-118.68° was 1.86±1.17mm. For patients with the L5/S1 segment operation, the average SAPR is 4.81±2.17mm. The SAPR of the patients with surgical segment ILA of 54.48-86.22° was 7.22±0.79mm. That of the patients with surgical segment ILA of 87.30-98.60° was 5.72±1.06mm. That of the patients with surgical segment ILA of 98.80-107.06° was 4.43±0.90mm. That of the patients with surgical segment ILA of 108.53-141.00° was 1.98±1.26mm. Interestingly, the ILA is also closely related to the operation time and operation difficulty score(P<0.05).
Conclusions:
Smaller ILA tends to be associated with more SAPR during the PEID. In addition, The smaller the ILA, the more difficult it is to expose the key anatomical structures, which leads to an increase in operation difficulty and longer operation time.
COT2DNet: Contextual 2D Attention for Scene Text Recognition
Authors: Qian Yefei , Ibrayim Mayire , Hamdulla Askar , Zhang Chunhu 
Published: October 2023

Abstract
Although scene text recognition (STR) methods have made great progress, reading the text of irregularly shaped scenes remains a challenge. The current conversion of two-dimensional (2D) images to one-dimensional (1D) feature maps for sequence recognition may lose a large amount of spatial information and cannot recognize text with a large degree of curvature. In this paper, we propose an network infrastructure to recognize texts of arbitrary shapes, named Contextual 2D Attention for Scene Text Recognition Network (COT2DNet). Firstly, deformable convolution is added to the feature extraction module, which can perform feature extraction according to the shape of the character and expand the receptive field of feature extraction, in the Transformer encoding stage, the multi-head attention is changed to Contextual 2D Multi-head Attention (COT2D), which can makes full use of contextual information between Q,K,V neighbouring keys to facilitate attentional learning, which improves the model's ability to perceive contextual information in text image recognition tasks, and at the same time can effectively learn complex background image feature representations. Due to the full-image propagation property, it may be inefficient to capture short-term dependencies using multi-stacked attentional blocks, and Multiscale position feedforward (CFEED) is used to acquire short-term dependencies for 2D images. Thus, the model can capture features of text images at multiple scales. Experiments show that, together with a visual model-based recogniser, COT2DNet significantly improves lexical contextual links, achieving state-of-the-art performance in public benchmarking.
Anaerobic Digestion of Macrophytes (Lemna Minor, Spirodela intermedia, Spirodela Polyrhiza and Wolffia Columbiana) And Anaerobic Sludge From Uasb Reactor: Effect of I/S Ratio (Inoculum/substrate) and Temperature
Authors: Hoyos Nestor Leonel Muñoz , Júnior Jose Carlos Alves Barroso , Silva Maria Cristina de Almeida , Monteggia Luiz Olinto 
Published: October 2023

Abstract
The present study aimed to explore floating macrophytes biogas and methane production potential (Lemna minor, Wolffia columbiana, Spirodela polyrhiza, and Spirodela intermedia) through the digestion process using anaerobic sludge from a UASB reactor as inoculum. Substrate (macrophytes) and inoculum (anaerobic sludge) came from domestic wastewater treatment. Two exploratory trials were conducted at different operating conditions to determine their influence on biogas and methane production. The assays were carried out using biodigesters with a volume of 50 liters and operated in batches, using macrophyte in nature. The experiments were carried out in triplicates for blank (anaerobic sludge) and different I/S ratios (inoculum/substrate). In Test 1, who evaluated four I/S ratios (0.5, 1.0, 1.5, and 2.0), biodigesters operation occurred under winter temperature conditions (mean 18±2.4°C) for 66 days. Test 2 evaluated the effect of temperature on biogas and methane production in the biodigesters. This experiment maintained the same I/S ratios of Test 1, but at summer temperature (26.6±1.1°C), and the duration of the batches was 37 days. The results obtained in the operational conditions tested in this work indicated that the biomass of macrophytes contributed positively to the increase in biogas and methane production. The highest yields (YCH4) achieved in winter and summer conditions were for I/S=2.0 with 184 NmL CH4/gVS and for I/S=1.0 with 323.3 NmL CH4/gVS, respectively. It evidenced that biogas and methane production varied in function of the operational parameter I/S that determines the amount of substrate fed in the biodigesters and the test application temperature.
Comparison of CRIB-II with SNAPPE-II as predictor of mortality and neurodevelopmental outcome at 12 months of age for newborns ≤ 32 weeks of gestational age
Authors: Bayen Abhinandan , Sk Md Habibullah , Chaudhuri Saugata , Saha Bijan 
Published: October 2023

Abstract
Premature births before 32 weeks of gestation pose a significant challenge in perinatal healthcare, with an increasing global trend. To ensure appropriate care and resource allocation, assessing the severity of neonatal illnesses is crucial. In this context, the study assessed CRIB-II and SNAPPE-II, two widely used scoring systems for newborn illness severity. These systems consider both perinatal and postnatal variables, providing comprehensive assessments. This prospective observational study conducted in an Eastern Indian tertiary care children's hospital between February 2021 and August 2022 aimed to evaluate and compare the predictive capabilities of two scoring systems, CRIB-II and SNAPPE-II, for in-hospital mortality and long-term neurodevelopmental outcomes in preterm infants born before 32 weeks of gestational age. Results showed that both CRIB-II (AUC of 0.862, 95% CI: 0.745–0.939) and SNAPPE-II (AUC of 0.919 95% CI: 0.816–0.975) demonstrated similar predictive abilities for neonatal mortality (difference: 0.057, 95% CI: -0.044 to 0.16, p-value 0.268). However, when it came to predicting long-term neurodevelopmental outcomes at 12 months corrected gestational age, SNAPPE-II maintained significance, while CRIB-II did not. The discrepancy in their performance over time emphasizes the complexity of predicting long-term outcomes in very preterm infants. Conclusion: This study suggests that CRIB-II and SNAPPE-II are comparable in predicting neonatal mortality. Given their similarity, CRIB-II may be preferred for its practicality in high-capacity NICUs. However, further research is needed to assess these systems' utility in comparing later neurodevelopmental outcomes and to explore the impact of new factors on their predictive accuracy.
The presence of a pet dog is associated with a more balanced response to a social stressor
Authors: Morris Kevin , Gandenberger Jaci , Ledreux Aurelie , Taeckens Ashley , Murphy Kerry , Forkin Jenni , Gilmore Anah 
Published: October 2023

Abstract
Acute and chronic stress have physical manifestations in the human body that can lead to many negative health impacts. Today, people around the world report and experience higher stress levels than ever before, spurring the search for non-pharmaceutical interventions to maintain healthy stress levels. In this study, we examined whether a pet dog's presence influences healthy adults' acute stress responses. Participating pet dog owners were randomly assigned to undergo the Trier Social Stress Test either with their pet dog or alone. Participants undergoing the acute psychological stressor with their pet dogs present had significantly lower heart rates, lower plasma cortisol response, and higher salivary alpha-amylase response than people without their dogs. Those who participated without their dog had a statistically flat alpha amylase response, which is typically associated with extreme or pathological stress. These findings extend the potential effect of pet dogs beyond merely lowering their owner’s stress levels to maintaining a healthier, balanced response across the sympatho-adrenal medullary axis and hypothalamic-pituitary axes.
New-Onset Seizure in a Case with 109 kb Interstitial Deletion of Chromosome 7q33: Case Report
Authors: Almalki Ashwaq , Castello Michael , Peters Jonathan , Alhasanat Odai , Bui Jonathan 
Published: October 2023

Abstract
We report a case of interstitial deletion of chromosome 7q33 in a 4-year-old male who had dysmorphic features such as microcephaly, short stature, developmental and language delay, and a new-onset seizure with status epilepticus. This deletion is unique because it is the smallest deletion reported to date within this region of chromosome 7. We aim to expand the knowledge base of this deletion and to further characterize its neurological phenotypes.
We present a case of interstitial deletion involving chromosome 7q33 in a 4-year-old male exhibiting dysmorphic features, including microcephaly, short stature, developmental and language delays, and a recent onset seizure progressing to status epilepticus. This deletion stands out as the smallest one documented within the 7q33 region to date. Our objective is to enhance the understanding of this deletion and provide a more comprehensive characterization of its associated neurological phenotypes.
Aggregating the response in time series lag models using Quad weight kernel: Impact of Environmental Factors on Schizophrenia Admissions
Authors: Thomas Jobin , Parameswaran Murali 
Published: October 2023

Abstract
In time series data where a data point has a delayed impact on dependent variables, distributed lag models (DLM) such as Distributed Lag Non-linear Model (DLNM) and Autoregressive Distributed Lag (ARDL) are applicable. Several articles have shown the impact of air pollutants and atmosphere factors like temperature and relative humidity on health. In this paper, we use environmental data (pollutants & climate variables) and daily hospital admissions of schizophrenia patients, to analyze the impact of pollution and climate factors on the hospital admissions in Bengaluru, India. In this work, we are using Number of Admissions (NoA) to hospitals as a proxy for the incidence of schizophrenia emergence. We have explored the applicability of Non-linear ARDL and aggregating responses in DLNM (DLNM-Ag.R) technique. DLNM-Ag.R using Epanechnikov kernel showed improved performance over DLNM by 25%, 15%, 17% and 72% for performance metrices MSE, MAE, MAPE and R2 respectively. Within aggregation methods, we have introduced a quad-weight kernel that further improved performance over Epanechnikov kernel by 17% in terms of MSE.
Immune recovery uveitis in Whipple’s disease: an unusual ocular presentation
Authors: LEQUAIN Hippolyte , ABRAMOWICZ Stéphane , SEILLER Julien , ABUKHASHBAH Amro , BURILLON Carole , VIGNOT Emmanuelle , BRUNET Olivier , SÈVE Pascal 
Published: October 2023

Abstract
Purpose
To describe an unusual case of Whipple’s disease (WD) complicated by uveitis, and subsequent paradoxical worsening after effective antibiotic treatment targeting Tropheryma whipplei (TW).
Methods
Case report.
Results
A 53-year-old male presented with bilateral knee arthritis, weight loss, chronic low-grade fever, and cognitive disorders. He was under treatment with tumor necrosis factor α inhibitors (TNFi) for seronegative spondyloarthritis. Given this unusual clinical presentation, further investigations were performed and revealed blood, saliva, stool, synovial fluid and cerebrospinal fluid positivity for TW, confirming the diagnosis of systemic WD. Ophthalmologic examination revealed bilateral posterior uveitis and an aqueous humor sample confirmed the presence of intraocular TW. TNFi were stopped, and the patient was subsequently treated with adequate antibiotics (ceftriaxone, followed by doxycycline and hydroxychloroquine), and subconjunctival corticosteroid injections. After a transient improvement of the ocular symptoms, he presented a recurrence of posterior segment inflammation, leading to repeated PCR testing for TW which were negative. Therefore, paradoxical worsening of the inflammation in the context of immune recovery uveitis (IRU) was thought to be the culprit. The patient was treated with systemic corticosteroid therapy, allowing for rapid improvement of the ocular findings.
Conclusions
This case underlines the possibility of IRU complicating WD. Ophthalmologists, rheumatologists, and internists should be aware of this rare complication, particularly in the context of previous immunosuppressive therapy.
ETFE RFID Tag with heteroatom-doped conductive carbon by screen print
Authors: Fu Hao , Chen Guang , Gao Junchang , Wu Yadong 
Published: October 2023

Abstract
The Radio Frequency Identification (RFID) tag in Internet of Things (IoT) applications lacks high-performance substrates to meet the growing demand. Surprisingly, ethylene tetrafluoroethylene copolymer (ETFE) is the strongest and toughest fluoroplastic, which maintains good heat resistance and chemical resistance, possessing strong mechanical properties as well, suiting for RFID tag substrate materials. Herein, we have demonstrated a simple route for the made of RFID tag via self-made ETFE membrane and heteroatom-doped conductive carbon screen printing technology. The ETFE membrane that can be produced on a large scale by using extrusion calendaring method.The highly conductive heteroatom-doped conductive carbon is produced using solvothermal method. Using simple screen printing technology prepare the RFID tag. The ETFE membrane exhibits excellent mechanical properties, combined with the excellent conductivity of heteroatom-doped conductive carbon, providing a high-quality and high-performance substrate selection for RFID tag.
Impact of upper tract urothelial carcinoma history on patients with non-muscle-invasive bladder cancer undergoing intravesical chemotherapy
Authors: Wang Fei , Ji Jiaxiang , Lai Chin-Hui , Wang Mingrui , Hu Haopu , Song Yuxuan , Du Yiqing , Xu Kexin , Hu Hao , Xu Tao 
Published: October 2023

Abstract
Purpose: This study was designed to evaluate the impact of upper tract urothelial carcinoma (UTUC) history on prognosis in patients with non-muscle-invasive bladder cancer (NMIBC) receiving intravesical chemotherapy.
Patients and methods: We conducted a single center, retrospective study of 444 NMIBC patients who received intravesical chemotherapy after transurethral resection of the bladder cancer at Peking University People's Hospital from 2000 to 2015. Patients were divided into UTUC-NMIBC group (with UTUC history) and primary NMIBC group (without UTUC history). Demographic, clinical and pathologic factors were analyzed. Kaplan–Meier curves and the log-rank test were used to depict and compare recurrence-free survival (RFS) and progression-free survival (PFS) between the two groups. Multivariable Cox regression models were constructed to determine the variables associated with RFS and PFS.
Results: Compared to the primary NMIBC group (n=410), the UTUC-NMIBC group (n=34) had an older median age (median age, 72.0 [65.0-81.0] vs 66.0 [58.0-75.0] years; P=0.007), a higher incidence of multiple tumors (52.9% vs 33.9%; P=0.026) and a higher recurrence rate (52.9% vs 30.7%; P=0.008) and worse RFS (P<0.001). In multivariate analysis, UTUC history was an independent risk factor for recurrence (hazard ratio=2.257; P=0.001), but not for progression. Interestingly, subgroup analysis indicated recent UTUC history (≤24 months between UTUC and NMIBC diagnoses) were associated with increased recurrence rates (73.7% vs 26.7%; P=0.014).
Conclusion: Presence of UTUC history was an independent risk factor for recurrence in patients with NMIBC who received intravesical chemotherapy, which should be considered when developing treatment plan.
Saikosaponin B1/D alleviate dextran sulfate sodium- induced colitis via regulating the NRF2/HO-1 pathway to inhibit the ferroptosis in zebrafish
Authors: Hu Huimei , Zheng Kangdi , Xu Xiaoying , Li Boyi , Yin Qiuxiong , Zeng Haizhou , Jiang Yupeng , Zhang Zhao , Ma Sheng-Suo , Chen Tao , Qian Guoqiang 
Published: October 2023

Abstract
Background: Inflammatory bowel disease (IBD) is a chronic and recurrent gastrointestinal inflammation, the pathophysiological mechanisms of that is not fully understood, and the current conventional treatment drugs are often associated with serious side effects. Saikosaponins(SSs) are the main active component of Bupleurum chinense DC. (BC). Saikosaponin A has been reported to have a positive effect on the remission of DSS induced colitis.
Aim: However, the studies on the mechanism and safety of SSs are still limited.
Materials and methods: We established zebrafish colitis model induced by sodium glucan sulfate (DSS) and gave intervention treatment with different saikosaponins.
Results : It was found that saikosaponin B1 (SSB1) and saikosaponin D (SSD) had the most prominent inhibitory ability on neutrophils infiltration in the larval intestine among the 6 saikosaponin monomers. In this study, we explored the effect and mechanism of SSB1 and SSD on DSS induced colitis in zebrafish. The results showed that both SSB1 and SSD could reduce the histological injury, tissue inflammatory cytokines and ROS expression in zebrafish. Moreover, we observed that both SSB1 and SSD significantly inhibited ferroptosis in DSS stimulated zebrafish colitis. In Conclusion: conclusion, our results suggested that Saikosaponin B1/D play a protective role in inhibiting ferroptosis by up-regulating NRF2/HO-1 pathway.
Whether vasectomy affects male sexual function and whether depression and anxiety occur after the procedure？
Authors: Fang Yang , Meijing Wang , Xiucheng Lan , Junjun Li , Liang Dong , Chunyan Fang , Degui Chang , Xujun Yu 
Published: October 2023

Abstract
A considerable number of male patients express apprehension regarding the potential correlation between vasectomy and sexual functionality, and worrying about affecting the couple's quality of sexual life and causing anxiety and depression. We investigated 306 male patients who sought vasectomy surgery between March 2016 and February 2022 at the Reproductive Women and Children's Hospital affiliated with Chengdu University of Traditional Chinese Medicine. We assessed patients' postoperative erectile status, ejaculation status, and depression and anxiety mainly by means of rating scales, including International Index of Erectile Function-5 (IIEF-5), the Chinese Index of Premature Ejaculation (CIPE), Zungs Self-Rating Depression Scale (SDS), and Self-Rating Anxiety Scale (SAS). Descriptive statistics (t-test, analysis of variance, rank sum test) detail the effect of vasectomy on IIEF-5, CIPE, SDS, SAS in men of different age groups.The results of age analysis showed that IIEF-5 and CIPE scores improved before and after ligation in different age groups (P < 0.05), with IIEF-5 scores improving the most in the age range of 30–39 years (205, 66.34%) (P = 0.00);Vasectomy does not affect male sexual satisfaction or erections, increases male patients' sexual confidence and desire, and does not cause or increase anxiety or depressive symptoms in men.
Exploring the Potential of Residual Impurities in Germanium Detectors for Low-Mass Dark Matter Detection
Authors: Mei Dongming 
Published: October 2023

Abstract
The pursuit of low-mass dark matter detection hinges on achieving an unprecedentedly low energy detection threshold. Germanium (Ge) detectors, when meticulously tailored with precise impurity compositions, hold the promise of expanding their sensitivity to energy levels below the sub-electronvolt (sub-eV) range. In this study, we embark on an exploration of residual impurities inherent to Ge detectors, focusing on their behavior at helium temperatures. These impurity atoms undergo a captivating freeze-out phenomenon, transitioning into localized states known as excited dipole states. Through compelling evidence derived from the measurement of relative capacitance, we elucidate the transition of impurity atoms from free charge states to these localized dipole states, as the temperature plummets from 11 K to 6.5 K. Our investigation encompasses the intricate formation of these dipole states in both n-type and p-type impurities. Furthermore, we shed light on the electric field generated by these dipole states, unveiling their capacity to ensnare charges and foster the creation of cluster dipole states. Drawing from prior measurements, we affirm that these excited dipole states exhibit a binding energy of less than 10 meV, thus forging a path toward an exceptionally low detection threshold for low-mass dark matter. Capitalizing on this concept, we propose the development of a 1-kg Ge detector equipped with internal charge amplification, an innovative approach poised to surpass electrical noise and, in turn, empower the detection of low-mass dark matter with unprecedented sensitivity.