bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Pleistocene tectono-stratigraphic evolution of the northern Po Plain (Italy) around the Castenedolo and Ciliverghe hillocks
Authors: Aghib Fulvia S. , Muttoni Giovanni , Norini Gianluca , Mariani Guido S. , Zerboni Andrea , de Franco Roberto , Di Capua Andrea , Tira Marco A. , Brusamolino Alessio , Menici Simona , Caielli Grazia , Groppelli Gianluca , Piccin Andrea 
Published: November 2023

AbstractWe studied the Pleistocene subsurface stratigraphy of an area in the northern Po Plain around the isolated tectonic hillocks of Castenedolo and Ciliverghe (Brescia, Italy) in order to estimate their long-term rates of tectonic deformation. Integrated stratigraphy of a new 100-m-long core (RL13) allowed better definition of the regional Y (0.45 Ma) and R (0.87 Ma) surfaces and the related magnetostratigraphically calibrated PS1, PS2, and PS3 depositional sequences. The Y surface in the RL13 core was placed at the base of the PS3 proximal braided river system that was deposited during middle Pleistocene within the Brunhes chron. The R surface is considered to be eroded within the PS2 braid-plain deposits at ca. 0.87 Ma between the top of Jaramillo subchron and the Bruhnes chron during the late Early Pleistocene.Based on different datasets, we evaluated the sedimentation rate, which has decreased from 0.09 mm/yr with deposition of PS2, to 0.06 mm/yr with deposition of PS3. The tectonic uplift, with an average rate of ~0.1 mm/yr in the last ca. 0.87 Ma, is interpreted to be associated with a fault and related fault-propagation folding. The Castenedolo and Ciliverghe hillocks then formed due to tectonic uplift during a change in the sedimentation regime since 0.45 Ma.
Playing Hopscotch on Dangerous Ground: Site-Based, Transit-Oriented Opera in Los Angeles
Authors: Aviles-Rodriguez Guillermo 
Published: November 2023

AbstractHopscotch: An Opera for 24 Cars was a celebrated site-based and technetronic musical performance that sought to bring opera into various communities in Los Angeles, many of which were economically disadvantaged. In the process, this opera set off a firestorm of protests that ultimately resulted in confrontations with community members, protests that would test the very premise of the dissemination of opera and performance outside spaces of privilege and in communities of colour. Informed by the concept of transit-oriented performance, this article analyses some ways in which neoliberalism is distorting opera's modern-day resonances.
Material dialogues for first-order logic in constructive type theory: extended version
Authors: Wehr Dominik , Kirst Dominik 
Published: November 2023

AbstractDialogues are turn-taking games which model debates about the satisfaction of logical formulas. A novel variant played over first-order structures gives rise to a notion of first-order satisfaction. We study the induced notion of validity for classical and intuitionistic first-order logic in the constructive setting of the calculus of inductive constructions. We prove that such material dialogue semantics for classical first-order logic admits constructive soundness and completeness proofs, setting it apart from standard model-theoretic semantics of first-order logic. Furthermore, we prove that completeness with regard to intuitionistic material dialogues fails in both constructive and classical settings. As an alternative, we propose material dialogues played over Kripke structures. These Kripke material dialogues exhibit constructive completeness when restricting to the negative fragment. The results concerning classical material dialogues have been mechanized using the Coq interactive theorem prover.
What Determines Social Service Workers’ Wages: A Cross-Country Analysis Using a Luxembourg Income Study
Authors: Lee Sung-Hee , Yun-Young Kim 
Published: November 2023

Abstract
The study is aimed at exploring the influencing factor of wages among social service workers (SSWs) through a cross-country analysis. Using Luxembourg Income Study data, two aspects are emphasised: first, the trends and patterns of wage levels among SSWs. Second, the determining factors that influence their low wages at a cross-national level and how those factors are intersectionally intertwined to exacerbate the wage level. Three significant findings are confirmed: a universal gendered wage gap; a more significant wage gap for those on part-time and/or fractured contracts and employed in the private sector; and a substantial association between a higher education and higher wages. Two policy concerns are raised for discussion: first, tackling the gendered wage gap and ensuring more secure employment, and a guaranteed living wage for those employed in the private sector. Second, enhancing the professionalism for empowering their effective choices in the labour market is essential.
The Interactions Between Ocean and Three Consecutive Typhoons Affecting Northeast Asia in 2020 From a Model Perspective
Authors: Liu Xin , Sun Chenghu , Zuo Jinqing 
Published: November 2023

AbstractIn August 2020, the historical warmest upper‐ocean thermal condition occurred in the western North Pacific (WNP), along with three tropical cyclones (TCs, namely Bavi, Maysak, and Haishen) generated in the WNP and affected Northeast China and the Korea peninsular (KP), within an unprecedentedly short span of 12 days from late August to early September of 2020. Meanwhile, prior to the formation of Bavi, a series of extreme warm mesoscale oceanic eddies were also observed over the WNP, and clearly sea surface cooling was detected after the passage of the three TCs. However, it remains unknown whether the warmest WNP with extreme warm mesoscale oceanic eddies has a modulation effect on intensity change of the three TCs. The results of sensitive experiments with fixed atmospheric initial conditions revealed that the historically warmest upper‐ocean thermal condition in the WNP in August 2020 might have contributed to increasing the intensity of three TCs by 5.3–10.0 hPa compared to normal ocean thermal conditions. The simulation results indicated that the extreme warm mesoscale eddy conglomeration might assist in intensifying the three TCs when they passed over these warm mesoscale eddies. Whereas the cold wake over the East China Sea caused by preceding TCs, Bavi and Maysak, might partly aid in weakening subsequent TCs in the decaying period. Furthermore, the simulated bias in the intensity evolution of the three TCs and the possible cause of minor differences in the simulated tracks and large‐scale steering flow between the sensitive and control experiments were discussed.
Transcriptional profiling of early differentiation of primary human mesenchymal stem cells into chondrocytes
Authors: Schwarzl Thomas , Keogh Andrea , Shaw Georgina , Krstic Aleksandar , Clayton Elizabeth , Higgins Desmond G. , Kolch Walter , Barry Frank 
Published: November 2023

AbstractArticular cartilage has only very limited regenerative capacities in humans. Tissue engineering techniques for cartilage damage repair are limited in the production of hyaline cartilage. Mesenchymal stem/stromal cells (MSCs) are multipotent stem cells and can be differentiated into mature cartilage cells, chondrocytes, which could be used for repairing damaged cartilage. Chondrogenesis is a highly complex, relatively inefficient process lasting over 3 weeks in vitro. Methods: In order to better understand chondrogenic differentiation, especially the commitment phase, we have performed transcriptional profiling of MSC differentiation into chondrocytes from early timepoints starting 15 minutes after induction to 16 hours and fully differentiated chondrocytes at 21 days in triplicates.
Reproducibility of pulmonary function tests in patients with systemic sclerosis
Authors: Jacquerie P. , André B. , De Seny D. , Henket M. , Giltay L. , Ernst M. , Louis R. , Malaise M. , Ribbens C. , Guiot J. 
Published: November 2023

AbstractSystemic sclerosis (SSc) is a rare autoimmune disease in which interstitial lung disease (ILD) is the leading cause of morbidity and mortality. Clinical management of the lung disease is mainly based on pulmonary function testing (PFT) and their changes over time. Little is known about the reproducibility of PFT testing in SSc patients. The aim of this study was to assess the test–retest reliability and reproducibility of PFTs in SSc patients with or without ILD over 30 days in order determine the potential physiologic variation over the time. We performed prospective observational study of SSc patients. The FVC, FEV1/FVC ratio, DLCO and KCO parameters were assessed in this population at four different timepoints; T0 (time 0) and H3 (T0 + 3 h) defined test–retest reliability, D15 (T0 + 15 days) and D30 (T0 + 30 days) for reproducibility. A mixed linear model was used to test the effect of time (and therefore reproducibility) on patients and we looked for an interaction. We included 25 SSc patients divided in two groups, 14 with ILD and 11 non-ILD. Interactions between time and group were not significant and were not reported. Time and group did not significantly influence the different measures of the PFT: FVC [p values time and group effect respectively (0.33; 0.34)], FEV1/FVC ratio (0.093; 0.056) and DLCO (0.99; 0.13) in the ILD and non ILD group (Table S2). The analyse with interactions between time and group were not significant and are not reported. We also used a Bland Altman test to assess reproducibility for FVC (L) and DLCO (mMKpa/min/L), Figs. 1 and 2 respectively. The measurements were therefore reproducible over time and in each group. PFT parameters are reproducible over time in a clinically stable population of SSc (no significant effect of the time T0, H3, D15 and D30) and there is no significant distinction between patients with ILD and no ILD. These respiratory functional data can further underline their use in clinical practice.
Relationship between autistic traits and letter-recognition under attention to face-likeness: study using a henohenomoheji-type compound stimulus
Authors: Sugiyama Midori , Fujii Shinya , Mori Masaki 
Published: November 2023

AbstractThis study aimed to clarify the relationship between autistic traits and letter information processing, specifically, the components of faces when attention is paid to face-like information. We created a new “henohenomoheji-type compound stimulus,” in which letters are placed in positions in such a way as to resemble a face. In Experiment 1, we examined the relationship between autistic traits and the participants’ performance in a letter-recognition task in which a henohenomoheji-type compound stimulus was used. The results showed a significant moderate negative correlation between Autism-Spectrum Quotient-Japanese Version (AQ-J) scores and letter-recognition sensitivity when the compound stimuli were arranged like a face. The letter-detection task was employed in Experiment 2 to examine how autistic traits affect tasks' performance with a lower cognitive load than in Experiment 1. We found no correlation between AQ-J scores and letter-detection sensitivity with or without face-like features. These results suggest that paying attention to faces reduces the participants’ performance in letter recognition, which represents a higher cognitive load in individuals with higher autistic traits. A major implication of this study is that the henohenomoheji-type compound stimuli can be applied to several cognitive tasks, such as cognitive processing in individuals with autistic traits.
Construction of Streptomyces coelicolor A3(2) mutants that exclusively produce NA4/NA6 intermediates of agarose metabolism through mutation induction
Authors: Kim Jina , Kim Eun Joo , Ko Hye-Jeong , Lee Yeon-Hee , Hong Soon-Kwang , Shin Miyoung , Lee Je Hyeon , Kwak Woori 
Published: November 2023

AbstractNA4/NA6, an intermediate degradation product of β-agarase, is a high value-added product with anticancer, anti-obesity, and anti-diabetic effects. Therefore, a method that enables the efficient production of NA4/NA6 would be useful from economic and medical perspectives. In this study, we aimed to generate aStreptomyces coelicolorA3(2) mutant M22-2C43 that produces NA4/NA6 as a final product; this method serves as a more efficient alternative to the enzymatic conversion of β-agarase for the generation of these products. The M22-2C43 strain was generated through two rounds of mutagenesis and screening for increased β-agarase activity and effective production of NA4/NA6. We assembled the complete genomes of two mutants, M22 and M22-2C43, which were identified following a two-round screening. Large and small genetic changes were found in these two mutants, including the loss of two plasmids present in wild-typeS. coelicolorA3(2) and chromosome circularization of mutant M22-2C43. These findings suggest that mutant M22-2C43 can produce NA4/NA6 as a degradation product due to functional inactivation of thedagBgene through a point mutation (G474A), ultimately preventing further degradation of NA4/NA6 to NA2. To our knowledge, this is the first report of a microbial strain that can effectively produce NA4/NA6 as the main degradation product of β-agarase, opening the door for the use of this species for the large-scale production of this valuable product.
Total Synthesis of Mavacuran Alkaloids via Bioinspired and Non-Bioinspired Strategies
Authors: Poupon Erwan , Evanno Laurent , Vincent Guillaume , Kouklovsky Cyrille 
Published: November 2023

AbstractIn this account, we report our endeavors towards the total synthesis of the mavacuran alkaloids and some of their highly natural complex bis-indoles. Our studies started with the hemisynthesis of voacalgine A and bipleiophylline, made an excursion to a related family of monoterpene indole alkaloids (total synthesis of 17-nor-excelsinidine) and ended with the total syntheses of several mavacuran alkaloids (16-epi-pleiocarpamine, 16-hydroxymethylpleiocarpamine, taberdivarine H, normavacurine, C-mavacurine, C-profluorocurine, and C-fluorocurine) via a combination of bioinspired and non-bioinspired synthetic routes.1	Introduction2	Bioinspired Hemisynthesis of Voacalgine A and Bipleiophylline3	Total Synthesis of the Mavacuran Alkaloids4	Bioinspired Oxidative Cyclization of a Geissoschizine Ammonium Derivative to Form the N1–C16 Bond and the E Ring5	Non-Bioinspired Michael Addition to Form the C15–C20 Bond and the E Ring6	Conclusion7	Epilogue
Recent Advances in Transition-Metal-Catalyzed Sonogashira Cross-Coupling Reactions of Alkyl Electrophiles
Authors: Liu Wei , Zhao Xian 
Published: November 2023

AbstractCatalytic Sonogashira cross-coupling reactions represent an efficient and versatile approach for constructing complex alkynes from readily available starting materials. Despite notable progress in this field, the development of transition-metal-catalyzed Sonogashira cross-coupling reactions of alkyl electrophiles remains limited. This limitation primarily stems from the low reactivity and pronounced propensity of these compounds towards β-H elimination. To overcome these challenges, researchers have investigated the use of palladium, nickel, and copper catalysts for Sonogashira reactions of alkyl electrophiles. Furthermore, significant strides have been made in achieving asymmetric Sonogashira cross-coupling reactions of electrophiles. This short review provides an overview of recent breakthroughs in this area.1	Introduction2	Palladium-Catalyzed Sonogashira Cross-Coupling of Alkyl Halides3	Nickel-Catalyzed Sonogashira Cross-Coupling of Alkyl Halides4	Copper-Catalyzed Sonogashira Cross-Coupling of Alkyl Electrophiles4.1	Copper-Catalyzed Racemic Sonogashira Cross-Coupling of Alkyl Electrophiles4.2	Copper-catalyzed Asymmetric Sonogashira Cross-Coupling of Alkyl Electrophiles5	Conclusions and Perspectives
Development of a D–D neutron spectrum detector based on helium-3 proportional counter
Authors: Yuan Guoliang , Wen Zuowei , Feng Lei , Luo Xiaobing , Wei Lingfeng , Zhang Jinwen , Zhao Wei , Yang Qingwei , Liu Yi 
Published: November 2023

Deuterium–deuterium (D–D) neutron spectrum diagnostics in tokamaks are a challenging task with current technologies. To address this issue, we designed and tested a fast and compact helium-3 proportional counter with a diameter of 2.5 cm and an effective length of 15 cm and using Kr as a stopping gas. The detector achieved a resolution of 96 keV for 2.406 MeV neutrons with a pulse shaping of 2 µs. Test results indicate that this detector has the potential to form a D–D neutron spectrometer for tokamaks, composed of detector arrays.
Temperature dependent charge carrier dynamics in 2D ternary Cu2MoS4 nanoflakes: An effect of electron-phonon coupling
Authors: Goswami Tanmay , Yadav Dharmendra Kumar , Bhatt Himanshu , Kaur Gurpreet , Ghosh Hirendra N. 
Published: November 2023

Two-dimensional transition metal chalcogenides (2D TMCs) like MoS2, WS2 etc., have established significant dominance in the field of nanoscience and nanotechnology, owing to their unique properties like strong light–matter interaction, high carrier mobility, large photo-responsivity etc. Despite the widespread utilization of these binary TMCs, their potential in the advancement of the optoelectronic research is limited due to the constraints in band tuning and charge carrier lifetime. To overcome these limitations, ternary transition metal chalcogenides have emerged as promising alternatives. Although, the optical properties of these materials have never been explored properly. Herein, we have investigated one such promising member of this group, Cu2MoS4 (CMS) using both steady state and time-resolved spectroscopic techniques. The material exhibits a broad range of visible light absorption, peaking at 576 nm. Photoluminescence spectroscopy confirmed the presence of both band gap emission and trap state-mediated emissions. Transient absorption spectroscopy unraveled the excited state charge carrier dynamics of CMS in sub-ps timescale, upon irradiation of visible light. We found significant influence of the trap mediated recombination, while Auger process being dominant at high charge density. We extended our study in a wide temperature range (5–300 K), which reveals the impact of electron-phonon coupling strength on the band gap and charge carrier dynamics of this material. This detailed study would draw more attention toward the unexplored optical properties of ternary 2D chalcogenides and will open new avenues for the construction of 2D material-based optical devices.
Finding a geographical basis for split noun phrases in the Netherlands and Belgium
Authors: Hendriks Lieke 
Published: November 2023

AbstractWhen considering the acceptance of split NPs, the Germanic language family reveals substantial variation. This is especially the case for Dutch as the observations seem rather contradictory, hence the question whether or not Dutch allows for split NPs. Via a large-scale questionnaire, the present study shows that some Dutch dialects allow split NPs to a larger extent than others, and that a geographical basis amidst the variation can be found in the southern regions of the Netherlands. These findings are crucial as they shed light onto the (syntactic) microvariation within the Netherlands which in turn leads to valuable insights into a future analysis of split NPs.
Left dislocation in Dutch
Authors: van Hinsberg Myrte , Hendriks Petra 
Published: November 2023

Abstract
Left Dislocation in Dutch is still poorly understood. In particular, it is unclear why speakers of Dutch use this construction and which factors influence its use. To obtain more insight in the function and use of Left Dislocation in Dutch, we elicited narratives from 30 adult speakers of Dutch and carried out an analysis of the use of Left Dislocation constructions in these narratives. Our analysis revealed that neither the introduction of new referents, nor the expression of a contrast between two referents, nor the marking of a shifted topic is able to explain all uses of Left Dislocation in these narratives. We speculate that the function of Left Dislocation in Dutch is to mark a referent as a potential topic for the further discourse.
Beyond politeness
Authors: Mulder Gijs , Sánchez Carrasco Patricia 
Published: November 2023

Abstract
Here we investigate the use of the politeness marker por favor ‘please’ in a corpus of contemporary Spanish dialogues from film scripts and literary dialogues. We argue that por favor is in fact only occasionally used as an expression of politeness. Apart from these uses, we distinguish between cases where por favor functions as a marker of illocutionary force and other discourse functions, that include the expression of impatience and disapproval. While the formulaic use of por favor is mainly limited to routine situations in the public sphere, the other functions are typical of private conversations. We argue that the ancient use of the expression can account for its contemporary non-polite uses.
Soundboard-using pets?
Authors: Bastos Amalia P. M. , Rossano Federico 
Published: November 2023

Abstract
The first studies that sought to establish two-way communication between humans and great apes led to important
findings but were nevertheless heavily criticized for their training methods, testing procedures, and claims. More recently,
hundreds of pet owners around the world have begun training domesticated animals to use Augmentative Interspecies Communication
(AIC) soundboard devices, contributing to the first ever large-scale study on interspecies communication. Here, we introduce our
scientific approach to our global citizen science project, where we will investigate how dogs and cats use AIC devices, building
an incremental research program starting from their associative learning of buttons to determining how AIC device use might impact
their welfare and their capacity for symbolic representation. We discuss how our multi-faceted approach can alleviate many of the
concerns regarding the original studies performed with apes, achieving larger sample sizes, ample documentation of training
techniques, and testing animals’ performance in controlled experimental settings.
Prevalence of HIV drug resistance among adolescents receiving ART in Cameroon with low- or high-level viraemia
Authors: Djiyou Armando B D , Penda Calixte I , Madec Yoann , Ngondi Grace D , Moukoko Astrid , Eboumbou Carole E , Aghokeng Avelin F 
Published: November 2023

Abstract

Objectives
To characterize HIV drug resistance (HIVDR) below and above the WHO threshold of 1000 copies/mL, considered for the definition of HIV ART failure in resource-limited settings.

Methods
From a cohort of 280 adolescents (aged 10–19 years) receiving ART for at least 6 months, genotypic resistance testing (GRT) was attempted for two groups of participants: participants with low-level viraemia [LLV; viral load (VL) 200–999 copies/mL] and those in virological failure (VF; confirmed VL ≥1000 copies/mL) using an in-house method. The Stanford HIValg Program was used to identify relevant HIVDR mutations and predict the efficacy of the newly introduced tenofovir-lamivudine-dolutegravir combination.

Results
GRT was successfully performed in 54/58 (93.1%) eligible participants, of which 28/31 (90.3%) were in VF and 26/27 (96.3%) had LLV. A high level of resistance was found both in adolescents with LLV and those in VF, with respectively 84.6% (22/26) and 75.0% (21/28) of participants harbouring at least one HIVDR mutation. NRTIs and NNRTIs were the most affected drug classes in both population groups. In contrast, PIs were not significantly affected and dolutegravir was expected to be active for all participants tested. However, for the newly introduced dolutegravir-based combination, functional monotherapy (dolutegravir only) was potentially possible for 22.7% (5/22) of the participants with LLV.

Conclusions
Our findings show that the 1000 copies/mL threshold is not an indicator of virological success and we call for a revision of the current WHO definition of VF in resource-limited countries.