bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of Institutionnal Factors on Climate Change Mitigation Strategies Amongst Rice Farmers in Nort-east Zone, Nigeria
Authors: Malabe K. M. , Ango A. K. , Yakubu D. H. 
Published: October 2023

Abstract

This study ascertained on-farm mitigation strategies to climate change effects amongst rice farmers, in North-East Zone, Nigeria. Multi-stage random sampling techniques was used to select 300 rice farmers. Data for this study were collected through primary and secondary sources. The analytical tools used to analyze the data obtained were descriptive (frequency count, percentages and weighted mean) and inferential (multiple regression analysis) statistics. The results of the institutional factors shows that majority (86.0%) of the rice farmers were members of cooperatives associations with 6–10 years of cooperative membership experience. The result further shows that all the rice farmers engaged labour on farm work and majority (90.0%) of them used family source of labour. About 17.7% of the rice farmers had access to credit facilities out of which majority (83.0%) of them obtained a loan of ₦200, 000 and below from their respective sources. Only few (9.0%) of the rice farmers had extension contact out of which 14.8% of them had contacts twice with extension agent during the period under review. Majority of the farmers’ level of use of climate change mitigation strategies fell within 1.0-1.70 mean value. Therefore, it is concluded that few rice farmers had access to agricultural loan facilities. Also, the level of use of climate change mitigation strategies were generally low. Therefore, it is recommended that there should be modalities that would provide an avenue for farmers to have easy access to agricultural loan facilities. Also, farmers should be encourage through awareness campaign to enhance their level of use of climate change mitigation strategies in order to effectively avert its adverse effects.
Construction of a lymphangiogenesis related gene score signature and prognostic model for bladder cancer
Authors: Chen Hao , Mao Longkun 
Published: October 2023

Abstract

Background: Lymph node metastasis is an important prognostic factor for bladder cancer patients, and the critical importance of lymphangiogenesis as an elemental process of metastasis has been reported. However, the effect of lymphangiogenesis genes on the prognosis of bladder cancer is still unclear.
Method: The gene expression and clinical data of bladder cancer patients were obtained from the TCGA database, and lymphangiogenesis-related genes were screened using univariate Cox regression analysis and LASSO analysis to construct a risk assessment model. The model was validated in the bladder cancer cohort patients in the GEO database. Finally, multi-omics analysis was performed to explore the predictive value of the model, and the transcriptional regulatory mechanism of related genes.
Results：We screened 17 lymphangiogenesis-related genes and established a risk score model for predicting survival in BCa patients. Better overall survival was observed in the low-risk group of both the training and test groups. A nomogram was developed to predict the survival outcomes of postoperative patients by integrating several clinical factors, and a well-predictive effect was observed. In addition, we performed drug sensitivity analysis to learn the chemosensitivity of each sample, assessed the relationship between the model and the immune microenvironment, and explored the specific signaling pathways involved in the prognostic model through enrichment analyses.
Conclusion: We developed a risk model using 17 lymphangiogenesis-related genes, which showed good predictive efficacy among both the internal and external validation groups. The clinical predictive value of the model was also explored in a multi-omics study.
Link between infrasound and rainfall variability of central region of Madagascar
Authors: RAMANANTSOA Andry Harifidy , RANDRIANARINOSY Fanomezana , RAKOTOARISOA Andriniaina Tahina , ANDRIANAIVOARISOA Jean Bernardo , RAMBOLAMANANA Gérard , RAZAFIMAMONJY Sandra 
Published: October 2023

Abstract

Thunderstorm is a well-known and permanent source of infrasound events. Infrasound signal propagation is known as well to be dictated by atmospheric parameters like temperature and wind. In tropical region like in Madagascar, rainfall pattern is one possible technique used to explain seasonal variation of IMS infrasound network detectability. In this study, 20 years of I33MG infrasonic station bulletin was correlated to rainfall data. Infrasound bulletin is obtained from DTKPMCC software in NIAB collection, atmospheric variations are derived from ECMWF ERA5 data and precipitation data are from local meteorological service of Madagascar. Observation of rainfall as well as infrasound bulletin from 2003 to 2022 shows a correlation between precipitation and infrasound events.
Comparative Analysis of Fecal Microbiota Between Infants With Cow Milk-induced Proctocolitis and Healthy Controls
Authors: Haytoglu Zeliha , Ozcan Dilek , Altıntas Derya Ufuk 
Published: October 2023

Abstract
Purpose
This study aimed to analyze the gut microbiota in stool samples from exclusively breastfed infants diagnosed with cow milk-induced allergic proctocolitis (CMIAP), with a focus on controlling potential factors that could interfere with the microbiota and to compare the findings with those derived from healthy infants.
Methods
16S-rRNA gene sequencing by Illumina MiSeq sequencing system was used to analyze the fecal microbiota. The β-diversity and α-diversity indices were determined to assess the species richness, evenness and group dissimilarities. The results were analyzed by QIIME 2 and R software. Linear discriminant analysis (LDA) and effect size analysis (LefSe) was performed to identify specific microbial taxa that significantly differed between the proctocolitis group and the healthy control group.
Results
25 infants including 16 infants with CMIAP and 9 healthy infants recruited. Bray-Curtis dissimilarity between the two groups was statistically significant (p-value = 0.001). At the phylum level, the proctocolitis group exhibited a significantly lower abundance of Actinobacteriota (LDA score 5.80 vs. 5.58, p = 0.001) and a higher abundance of Proteobacteria (LDA score 5.53 vs. 5.22, p = 0.044). At the class level, the proctocolitis group showed a higher abundance of Gammaproteobacteria (LDA score 5.57 vs. 5.17, p = 0.027) and lower abundances of Actinobacteria (LDA score 5.37 vs. 5.75, p = 0.0003) and Coriobacteriia (LDA score 4.56 vs. 4.93, p = 0.043). At the genus level proctocolitis group showed a higher abundance of Rumnicocus (LDA score 5.063 vs. 4.64, p = 0.035) and a lower abundance of Bifidobacterium (LDA score 5.63 vs 5.63, p = 0.0002)
Conclusions
The findings suggest significant differences in the gut microbiota composition between infants with proctocolitis and healthy infants. This study underscores the importance of studying the gut microbiota in proctocolitis and highlights the need for continued research in this field to better understand the complex interplay between gut microbiota and health outcomes in infants with proctocolitis.
Increased Hindbrain Motion in Chiari I Malformation Patients Measured Through 3D Amplified MRI (3D aMRI)
Authors: Abderezaei Javid , Pionteck Aymeric , Chuang Ya-Chen , Carrasquilla Alejandro , Bilgili Gizem , Lu Tse-An , Scadeng Miriam , Fillingham Patrick , Morgenstern Peter , Levitt Michael , Ellenbogen Richard , Yang Yang , Holdsworth Samantha , Shrivastava Raj , Kurt Mehmet 
Published: October 2023

Abstract
Chiari Malformation type 1 (CM-I) is a neurological disorder characterized by morphological defects including excessive cerebellar tonsillar ectopia and associated manifestations. We used 3D amplified MRI on a cohort of healthy and CM-I subjects to investigate the brain’s intrinsic motion, its association with the morphology and patient’s symptomatology, and surgical outcomes. We observed significantly higher anterior-posterior, superior-inferior, and medio-lateral displacements in the cerebellar tonsils and medulla (∼16%-∼73%) of the CM-I group. The ratio of neural tissue in the foramen magnum was correlated with the superior-inferior tonsillar motion (r=0.58). The tonsillar herniation was correlated with the anterior-posterior motion of the tonsils (r=0.61), and the anterior-posterior and medio-lateral motions of the medulla (r=0.66, and r=0.57). The medio-lateral motion of the tonsils was the only indicator of surgical outcomes (p=0.03, and AUC=0.95), with improved outcomes in subjects with larger motion.
Costs of Capital and Wealth Tax -- Remarks on Bjerksund and Schjelderup (2022)
Authors: Kruschwitz Lutz , Löffler Andreas , Lorenz Daniela , Uttscheid Moritz 
Published: October 2023

Abstract
This note incorporates wealth taxes in a simple asset valuation model based on discounted cash flows. Any valuation method requires an adjustment of pre-tax into post-tax costs of capital. By adopting the adjustment procedure proposed in previous literature, we show that arbitrage opportunities can occur - which is incompatible with a consistent valuation. In particular, such problems arise if a wealth tax system applies that uses current (instead of previous) stock prices as the basis for assessment. Furthermore, in this setting we derive a consistent relation between pre-tax and post-tax costs of capital that is compatible with the premise of no-arbitrage by exploiting risk-neutral probabilities.
Dynamic Bandwidth-aware Link Aggregation Control Algorithm for Self- Hosted Lms Data Center
Authors: Kunu Bright K. , Dagadu Joshua C. , Pomatse Stephen Kwaku , Boansi Oliver K. 
Published: October 2023

Abstract
Reliable network connectivity is an absolute requirement for running online Learning Management System (LMS). This is particularly important, but challenging for a self-hosted LMS which is characterized by growing number of users. As many self-hosted systems are fraught with low bandwidth and hence deliver poor quality service to end users. Link Aggregation Control Protocol (LACP) has been proposed as a networking technique that can effectively provide link reliability and improved bandwidth at a much reduced cost. Notwithstanding, traditional LACP implementation usually results in link redundancy due to poor configuration. This study proposes an algorithm that will allocate network bandwidth according to the dynamic behaviours of the LMS application. The dynamic bandwidth-aware LACP system was configured to dynamically assign network bandwidths according to the requirements of the LMS application instance. The system is simulated for a 2-LAG and 4-LAG setups using the SDN Ryu controller. The results of the simulation show that the proposed system is effective in assigning communication link bandwidth according to the dynamic needs of the LMS. Also, the system can quickly re-assign link bandwidth when one or two links are down. However, as the number of aggregated links increases, delays and packet retransmission rates also increase. This suggests that the number of links aggregated into a LAG should be carefully selected according to the SDN controller’s ability to fully utilize them to avoid link redundancy.
Associations between rat infestations and mental health vary by gender, race, and income in Chicago
Authors: Murray Maureen H , Byers Kaylee A , Buckley Jacqueline Y , Magle Seth B , German Danielle 
Published: October 2023

Abstract
Rats are an understudied stressor for people in urban environments around the world but the effects may not be distributed equally among residents. In this study, we examined associations between residential rat sightings and mental health in Chicago, where rat complaints are the highest of any American city. We examined how this relationship varied by frequency of rat sightings, race, ethnicity, income, home ownership, and gender and explored potential psychosocial pathways (e.g. feelings about the home) between rat sightings and mental distress. We conducted a randomized household survey along an income gradient in 2021 and asked about depressive symptoms in the past week (i.e. Center for Epidemiologic Studies Depression scale), frequency of rat sightings in/around the home, perceptions of rats, neighborhood conditions, and socio-demographic characteristics. We used logistic regression to assess relationships among these variables for our entire sample and for specific demographics using stratified models. Respondents (n = 589; 409 complete cases) who saw rats in/around the home daily/almost daily had 5.5 times higher odds of reporting high depressive symptoms relative to respondents who saw rats less frequently after accounting for socio-demographics and neighborhood conditions. This relationship was significant for men and respondents with lower incomes or race or ethnicity other than white. Our results show that rat infestations should be considered a threat to mental health among urban residents. Increased mental health support for residents living in rat-infested housing may improve public health in cities.
Higher cadmium exposure was associated with sex-specific thyroid dysfunction: Consistent evidence from two independent cross-sectional studies based on urinary and blood cadmium measurements
Authors: Shao Ranqi , Su Liqin , Wang Peng , Han Xu , Wang Ting , Dai Jun , Gu Yi , Luo Jiao , Deng Lifang , Liu Jingping 
Published: October 2023

Abstract
Population-based studies on the association between cadmium (Cd) exposure and thyroid function are limited and have shown conflicting results. Two independent cross-sectional studies using different Cd biomarkers were carried out in six rural areas with different soil Cd levels in China. Thyroid dysfunction was defined based on levels of thyroid stimulating hormone (TSH) and free thyroxine (FT4). Both multivariable linear regression, multiple logistic regression and restrictive cubic splines models were used to estimate the association between Cd and thyroid dysfunction. For both of the two independent studies, higher Cd levels were observed to be associated with lower TSH levels and higher risk of thyroid dysfunction. The negative relationship between urinary Cd and TSH was found in both total participants (β = -0.072, p = 0.008) and males (β = -0.119, p = 0.020) but not in females, however, the negative relationship between blood Cd and TSH was only found in females (β = -0.104, p = 0.024). Higher urinary Cd (> 2.52 µg/g creatinine) was associated with higher risk of thyroid dysfunction, while higher blood Cd was associated with higher risk of hyperthyroidism status. The adjusted Odds Ratio (OR) for the risk of hyperthyroidism status was 3.48 (95%CI:1.36–8.92) and 6.94 (95%CI:1.23–39.31) times higher with every natural log unit higher in blood Cd in total participants and males, respectively. Results from the two independent cross-sectional studies consistently suggested that higher Cd levels were associated with sex-specific thyroid dysfunction.
Exploring Patient’s Clinical Outcomes, Hospital Costs, and Satisfaction After the Implementation of Integrated Clinical Pathway-Based Nursing Practice Model
Authors: Rachmawaty Rini , Wahyudin Elly , Bukhari Agussalim 
Published: October 2023

Abstract
Introduction: The prevalence of non-communicable diseases in Indonesia tends to increase accompanied by an increase in the National Health Insurance claim costs by 18%-25% every year leading to the Indonesian government encouraging the use of clinical pathways to achieve optimal quality of health services.
Methods: The method used in this study was action research by developing, implementing, and evaluating the clinical guidelines and integrated clinical pathways (ICPs) for 10 diseases that were categorized as high volume, high risk, and high cost. Data was collected through observation and interviews and was analyzed using IBM SPSS Statistics version 28.
Results:A total of 40 patients from Haji Hospital (n= 20) and from Labuang Baji Hospital (n= 20) with diagnoses of pulmonary tuberculosis, pneumonia, dyspepsia, typhoid fever, normal delivery, and COPD were included and analyzed. Compliance with the ICPs in both hospitals is quite low, 50.02% in Haji Hospital and 44.46% in Labuang Baji Hospital. However, the length of patients’ stay (LOS) was found to be compliant and some exceeded the ICP standards. The patients’ hospital costs were found to be different in earning profit for all disease diagnoses. Patient satisfaction also improved with each diagnosis.
Conclusion: The implementation of ICP at both hospitals showed that all indicators of patient clinical outcomes improved according to the time specified in ICP, resulting in patients’ LOS being shorter than stipulated in ICP and an increase in patient satisfaction. ICP implementation has also led to hospitals earning different profits in almost all diagnoses.
Aromatherapy in a carcinoma patient with Malignant Fungating Wounds :a case report
Authors: Li Yan , Zhou Jingbo , Cheng Zijun , Du Xixi , Cheng Xin , Peng Wei 
Published: October 2023

Abstract
Malignant Fungating wounds is caused by tumor growth ,which give rise to skin damage, micro vascular rupture and tissue necrosis. The patient frequently suffer from pain, foul smell, functional impairment, bleeding as well as cataclysm due to necrosis and microbial contamination. Malignant Fungating wounds of patients can't heal definitely, Despite the symptom management and wound management strategies will improve quality of life and maintain personal dignity .Aromatherapy as an adjuvant treatment is used to relieve pain, remove odor and alleviate psychological distress on end-of-life care. The case is aim to analysis of a patient retrospective date using aromatherapy to deal with the symptoms of pain, bleeding and infection caused by Fungating Wounds. it was found that wound infection and pain were alleviated, psychological pain was relieved significantly and the patient's malignant wound was surprisingly healed by aromatherapy, which met patient’s hope of last stage .
Photodegradation of crystal violet by nitrogen-doped reduced graphene oxide/ZnO nanorod nanocomposites
Authors: Aghakhani Hamed , Babamoradi Mohsen , Azimirad Rouhollah , Safa Saeed 
Published: October 2023

Abstract
The photodegradation of crystal violet (CV) was studied by nitrogen doped reduced-graphene oxide (N-rGO)/ZnO nanorod nanocomposites. ZnO nanorods and N-rGOs were synthesized by hydrothermal method separately. N-rGOs were dropped on the ZnO nanorods via spin coater for synthesizing the nanocomposites. The X-ray diffraction (XRD) pattern and scanning electron microscopy (SEM) images revealed that ZnO nanorods are synthesized well. The photodegradation results showed that the 80% degradation of CV obtained after 120 min illumination of the best nanocomposite under 40W visible light.
Tumor-derived exosome miR-558 promotes angiogenesis in tongue squamous cell carcinoma by targeting HPSE
Authors: Ding Bixiao , Chen Qingwen , Li Xiaoguang , Wu Zhen , Ding Yuancheng , Wu Qiong , Han Liang , Wu Hao 
Published: October 2023

Abstract
Purpose
This study aimed to investigate the role of miR-558 in tumor angiogenesis by targeting heparinase (HPSE) in tongue squamous cell carcinoma (TSCC)-derived exosomes.
Materials and Methods
In the present study, the role of exosome miR-558 in angiogenesis in vitro and in vivo was investigated by cell proliferation, migration, tube formation, subcutaneous tumor formation in mice, and in vivo Matrigel plug assay. The target genes of miR-558 were detected by means of dual luciferase assay.
Results
It was found that TSCC cells secrete miR-558 into the extracellular environment, with exosome as the carrier. Human umbilical vein endothelial cells (HUVEC) ingested exosomes, which not only increased the expression level of miR-558, but also enhanced their proliferation, migration, and tube formation functions. In vivo Matrigel plug assay demonstrated that TSCC cell-derived exosome miR-558 promoted neovascularization in vivo. Compared with negative control cells, TSCC cells overexpressing miR-558 formed subcutaneous tumors in nude mice, with larger volume, heavier mass, and more vascularization. Dual luciferase assay confirmed that HPSE was the direct target gene regulated by miR-558. HPSE promoted the proliferation, migration, and tube formation of HUVECs, and the knockout of HPSE could down-regulate the pro-angiogenic effect of miR-558.
Conclusion
In summary, miR-558 in TSCC exosomes promotes the proliferation, migration and tube formation of HUVECs by targeting HPSE, and enhance tumor angiogenesis.
Comparison among oral lichen planus, lichenoid lesions and proliferative verrucous leukoplakia: a clinicopathological, transversal study
Authors: Moreira¹ Milena Duarte , Maia¹ Fernanda Doyle , Zimbrão Viviane Limongi , Collodetti¹ Emilly , Grão-Velloso¹ Tânia Regina , Barros¹ Liliana Aparecida Pimenta , Lourenço Simone , Camisasca Danielle 
Published: October 2023

Abstract
Background
Clinicopathological diagnosis and follow-up of oral lichen planus and leukoplakia are necessary due to its potential for malignant transformation and the need to differentiate it from other lichenoid diseases and proliferative verrucous leukoplakia. This study aimed to classify and compare sociodemographic and clinicopathological features among oral lichen planus, oral lichenoid lesions and proliferative verrucous leukoplakia.
Methods: A transversal observational study was conducted in which oral leukoplakia and oral lichen planus cases were surveyed at the Oral Pathological Anatomy Service and Applied Biotechnology Laboratory. Sociodemographic and clinicopathological data were compared regarding the lesions studied with the chi-square or Fisher’s exact test.
Results: After classification, 21 oral lichen planus, 34 oral lichenoid lesions and 12 proliferative verrucous leukoplakia cases were evaluated. Reticular patterns are more characteristic of oral lichen planus and plaque lesions of proliferative verrucous leukoplakia. Buccal mucosa was the most affected site in oral lichen planus lesions and they were bilateral in all cases. Epithelial dysplasia was present in almost all cases of proliferative verrucous leukoplakia.
Conclusion: Oral lichenoid lesions presented intermediate features when compared to oral lichen planus and proliferative verrucous leukoplakia. This may delay proliferative verrucous leukoplakia diagnosis.