bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kepastian Hukum Terhadap Kepemilikan Hak Atas Tanah Negara Oleh Masyarakat
Authors: Ahmadi Ahmadi 
Published: February 2024

Beberapa masyarakat yang menempati lahan tanah yang statusnya masih atas hak tanah Negara memberikan problem pada Pemerintah, pengawasan dan peraturan sudah di bentuk akan tetapi ketidaktahuan masyarakat dalam pengelolaan terhadap tanah Negara masih sangat minim. Untuk itu, dalam penelitian ini bertujuan memberikan informasi kepada masyarakat agar masyarakat mengetahui bagaimana proses pelaksanaan pengurusan surat-surat tanah terhadap tanah Negara, sedangkan untuk Pemerintah dapat mengetahui bagaimana hambatan-hambatan yang terjadi pada masyarakat dalam menguasai secara fisik atas tanah Negara dengan dasar peraturan Undang-Undang Nomor 5 Tahun 1960 Tentang Peraturan Dasar Pokok-Pokok Agraria dan Peraturan Menteri Agraria, Undang-Undang Nomor 11 Tahun 2020 tentang Cipta Kerja dan peraturan Tata Ruang/ Kepala Badan Pertanahan Nasional Nomor 18 Tahun 2021 Tentang Tata Cara Penetapan Hak Pengelolaan dan Hak Atas Tanah. Pendaftaran hak atas tanah di kantor ATR/BPN dapat dijadikan tujuan untuk masyarakat mendapat kepastian hukum hak atas tanah yaitu seperti kepastian objek tanah, kepastian hak kepemilikan dan kepastian subyek pemilik untuk meminimalisir adanya sengketa dalam masyarakat. Suatu hambatan-hambatan yang ada dilapangan seperti adanya birokrasi yang berbelit-belit dari oknum-oknum Pemerintah dan/atau pegawai Kantor ATR/BPN yang menghambat proses pendaftaran sertipikat tersebut, adapula hambatan seperti punguan liar dan biaya yang tidak jelas yang harus ditekan bahkan harus dihilangkan. Tahapan proses pendaftaran sampai menjadi sertipikat mekan waktu yang cuku lama waktu ini lah yang menjadi masyarakat enggan melakukan pengurusan pengurusan.
Temperature data for vine shade study
Authors: Millward Andrew 
Published: February 2024

<p>These are the raw data collected for the study published in: Millward, A.A.; Blake, M. When Trees Are Not an Option: Perennial Vines as a Complementary Strategy for Mitigating the Summer Warming of an Urban Microclimate. <em>Buildings</em> <strong>2024</strong>, <em>14</em>, 416. <a href="https://doi.org/10.3390/buildings14020416" target="_blank">https://doi.org/10.3390/buildings14020416</a> </p>
<p><br></p>
<p>This is the study abstract:</p>
<p><br></p>
<div> This study evaluates the potential of Boston Ivy (<em>Parthenocissus tricuspidata</em>) to reduce building surface temperature in a mid-latitude North American city center where vine use for this purpose is uncommon. Vegetation can regulate city summer temperatures by providing shade and evaporative cooling. While planting trees has been a focus for many urban municipalities, trees require space (above and below ground), access to water, costly planting and maintenance, and may only be desirable to some city residents. To explore viable vegetation alternatives with fewer growth constraints, we deployed temperature loggers on the exterior walls of buildings in the urban core of Toronto, Canada, a large mid-latitude city. Perennial vines shaded some walls, while others did not. These devices systematically tracked exterior surface temperature fluctuations over six months, including the growing season, with full vine-leaf coverage. During peak solar access periods, average daily temperature differentials between vine-shaded and non-shaded building surfaces ranged from up to 6.5 °C on south-facing building exteriors to 7.0 °C on west-facing walls. Models were developed to estimate daily degree hour difference, a metric integrating the magnitude and duration of the temperature-moderating potential of vines. At ambient temperatures ≥ 23 °C, solar radiation intensity and ambient air temperature were positively correlated with vine effectiveness in mitigating the rise in built surface temperature; relative humidity was negatively associated. Installing vine cover on urban buildings in the form of green façades can complement tree planting as cities become hotter due to climate change, and space for growing trees diminishes with urban densification. Future research into the capacity of green façades to regulate outdoor temperature must establish uniform measurement protocols and undertake evaluations in diverse climatic scenarios.</div>
HARTA TIDAK DITUNTUT: PUNCA DAN KAEDAH PENYELESAIANNYA
Authors: Nik Wajis Dr Nik Rahim 
Published: February 2024

Harta pusaka yang tidak dituntut atau harta â€˜pusaka bekuâ€™ sudah sekian lama menjadi masalah kepada masyarakat dan ianya menjadi semakin kronik sejak akhir-akhir ini ekoran jumlah kes yang semakin meningkat pada setiap tahun. Akibat dari itu maka timbullah pelbagai isu yang memberi kesan yang amat negatif kepada pihak-pihak yang terlibat khususnya ahli waris. Terdapat banyak faktor serta punca yang membawa kepada berlakunya keadaan ini; antaranya sikap acuh tidak acuh atau sambil lewa masyarakat dalam pengurusan harta pusaka milik mereka. Selain itu, ketidakfahaman masyarakat tentang kaedah dan cara serta prosedur yang perlu dilakukan untuk menguruskan harta pusaka juga merupakan faktor penyumbang kepada berlakunya isu harta pusaka yang tidak dituntut semakin bertambah di Malaysia. Keadaan ini tidak boleh dibiarkan dan perlu dicari kaedah dan mekanisma dalam menyelesaikan kemelut ini dari terus berlarutan. Artikel ini akan menfokuskan kepada perbincangan tentang punca-punca mengapa berlakunya isu harta yang tidak dituntut ini serta kaedah yang boleh diaplikasikan bagi membantu menyelesaikan dan mengurangkan masalah dalam isu harta yang tidak dituntut ini.
TINJAUAN KOREOGRAFI TARI LAMPAU BULAN DI SANGGAR SENI BANUA SANGGAM KABUPATEN BALANGAN
Authors: LEVIA SHERLY NUR , Purnama Asri Adinda Gita Kinanthi , Wijaya Andi 
Published: February 2024

Penelitian ini bertujuan untuk mengetahui (1) mendeskripsikan bentuk penyajian Tari Lampau Bulan di Sanggar Seni Banua Sanggam Kabupaten Balangan (2) meninjau koreografi Tari Lampau Bulan di Sanggar Seni Banua Sanggam Kabupaten Balangan. Metode penelitian z pendekatan Deskriptif Kualitatif. Teknik pengumpulan data yang digunakan adalah observasi, wawancara, dan dokumentasi. Hasil penelitian yang didapat adalah Tarian ini diawali dengan seorang penari yang pergi untuk mencari, memetik, memilah, merangkai, dan mearak bunga. Ragam gerak berjumlah 61 ragam gerak dengan 34 pola lantai dan diiringi musik berdurasi 6 menit 47 detik. Properti multifungsi karena menjadi kostum ketika keranjang ditempelkan dikopiah penari. Tinjauan koreografi Tari Lampau Bulan diteliti menggunakan prinsip Murgiyanto, yaitu: Kesatuan yang Utuh (Unity) yang dapat dilihat dari koreografi dan bentuk penyajian yang saling berhubungan, Keragaman (Variasi) gerak dengan tujuan agar koreografi tidak monoton seperti pembagian tempo dan dimensi, Pengulangan (Repetisi) gerak terjadi agar membantu koreografer dalam menyampaikan pesan tarian, Kontras yang dimaksud yaitu variasi dua ragam gerak yang dilakukan dalam waktu yang bersamaan, Transisi gerak bertujuan agar susunan gerak terlihat rapi dengan gerak-gerak penyambungnya, Urutan (Sequence) sangat penting agar penonton lebih mudah memahami aur dari cerita tari yang ditonton, Klimaks adalah tujuan penting dari tarian, Keseimbangan (Balance) pada jumlah penari tetapi dan penggarapan pola lantai, dan Harmoni adalah gabungan dari semua komponen menjadi satu yang saling melengkapi.
Stable and reproducible MIP-ECL sensors for ultra-sensitive and accurate quantitative detection of Estrone
Authors: Cao Jie , Chen Xiao-Ying 
Published: February 2024

Estrone (E1), as an endogenous estrogen, has a variety of physiological functions in human body and is of great significance to human health. On the other hand, it is a widely distributed and highly disturbing environmental endocrine disruptor in water. Therefore, there is an urgent need to develop a sensitive, rapid, and inexpensive method for the on-site determination of E1, which is not only for clinical diagnosis and treatment, but also for the investigation and monitoring of endogenous estrogen pollution in environmental water. In this study, Ru(bpy)32+/MWCNTs/Nafion/gold electrodes were prepared by surface electrostatic adsorption and ion exchange. A molecularly imprinted membrane (MIP) with the capability to recognize E1 molecules was prepared by sol-gel method, and the electrodes were modified with MIP to form an electrochemical luminescence sensor (MIP-ECL). This method simultaneously possesses ECL’s advantage of high sensitivity and MIP’s advantage of high selectivity. Moreover, the addition of carboxylated multi-walled carbon nanotubes (MWCNT-COOH) improved the functionalization of the gold electrode surface and increased the binding sites of MIP. Meanwhile, the good conductivity of MWCNTs promoted electron transfer and further improved the sensitivity of the sensor. The sensor showed a wide linear interval in which the E1 concentrations can range from 0.1 μg/L to 200 μg/L, along with a high linear correlation coefficient (R2 = 0.999). The linear regression equation of the sensor was Y = 243.64x-79.989, and the detection limit (LOD) was 0.0047 μg/L. To validate our sensor, actual samples were also measured by the reference method (LC-MS/MS), and it was found that the relative deviation of quantitative results of the two different methods was less than 4.1%. This indicates that the quantitative results obtained by this sensor are accurate and can be used for rapid in situ determination of E1 in clinical samples and environmental water.
Metabolites of intestinal fora can be used as diagnostic and progressive markers for mild cognitive impairment
Authors: Lu Liquan , Qin Lei , Zhao Xiaohui , Liu Zanhua , Qiu Xiaoting , Yang Shuo , Song Haihan , Yang Juan 
Published: February 2024

PurposeThe aim of the work was to analyze the metabolites of the intestinal microbiota from the patients with mild cognitive impairment (MCI) and progressive MCI due to Alzheimer’s disease (AD).MethodTwo cohorts were established. The first one included 87 subjects with 30 healthy controls (NC), 22 patients with MCI due to AD, and 35 patients with AD. The second cohort included 87 patients with MCI due to AD, who were followed up for 2 years and finally were divided into progressive MCI due to AD group (P-G) and unprogressive MCI due to AD group (U-G) according their cognitive levels. Fecal samples were collected to all patients at the baseline time point. Differential metabolites were subjected to pathway analysis by MetaboAnalyst.ResultsIn the first cohort, we found 21 different metabolites among the three groups (AD, MCI, and NC). In the second cohort, we identified 19 differential metabolites between the P-G and U-G groups. By machine learning analysis, we found that seven characteristic metabolites [Erythrodiol, alpha-Curcumene, Synephrine, o-Hydroxylaminobenzoate, 3-Amino-4-hydroxybenzoic acid, 2-Deoxystreptamine, and 9(S] were of characteristic significance for the diagnosis of MCI due to AD, and six metabolites (Indolelactate, Indole-3-acetaldehyde, L-Proline, Perillyl, Mesaconate, and Sphingosine) were the characteristic metabolites of early warning for the progression of MCI due to AD. D-Glucuronic acid was negatively correlated with Apolipoprotein E4 (APOE4). Perillyl alcohol was negatively correlated with all of the five biomarkers [P-tau181, Neurofilament light chain (NF-light), Aβ1-42, Aβ1-40, and glial fibrillary acidic protein (GFAP)], but Indoleacetaldehyde was positively correlated with three biomarkers (P-tau181, Aβ1-42, and GFAP). Three characteristic metabolites (3-Amino-4-hydroxybenzoate, 2-Deoxystreptamine, and p-Synephrine) were positively correlated with Aβ1-42. 2-Deoxystreptamine, 9(S)-HPOT, and Indoleacetaldehyde were positively correlated with GFAP. L-Proline and Indoleacetaldehyde were positively correlated with NF-light.ConclusionSpecific metabolites of intestinal fora can be used as diagnostic and progressive markers for MCI.
Secure dynamic event-triggering control for consensus under asynchronous denial of service
Authors: Amini Amir , Mohammadi Arash , Hou Ming , Asif Amir 
Published: February 2024

IntroductionThis article proposes a secure implementation for consensus using a dynamic event-triggered control (DETC) scheme for general autonomous multi-agent systems (MAS) under asynchronous (distributed) denial of service (DoS) attacks. The asynchronous DoS attacks can block each communication channel independently in an unknown pattern. Depending on the impact of DoS on the communication topology, the attacks are categorized into (i): connectivity-preserved DoS (CP-DoS), and (ii): connectivity-broken DoS (CB-DoS). In CP-DoS, the operating communication topology remains connected. On the other hand, in CB-DoS the adversary breaks the communication graph into isolated sub-graphs.MethodsThe DETC scheme is employed to reduce the control updates for each agent. To guarantee consensus under both the CP-DoS and CB-DoS, a linear matrix inequality (LMI) based optimization approach is proposed, which simultaneously designs all the unknown DETC parameters as well as the state feedback control gain.ResultsThe proposed optimization method prioritizes the minimum inter-event interval (MIET) between consecutive control updates. The trade-off between relevant features of the MAS, namely the consensus convergence rate, intensity of control updates, and level of resilience to DoS can be handled by the proposed optimization.DiscussionSimulation results quantify the effectiveness of the proposed approach, showcasing its ability to maintain secure consensus in MAS under varying DoS attack scenarios.
Peri-implantation estradiol level has no effect on pregnancy outcome in vitro fertilization- embryo transfer
Authors: Huang Pinxiu , Ou Yuan , Tang Ni , Chen Jing , Wen Qiuyue , Li Jingjing , Zeng Dingyuan 
Published: February 2024

BackgroundThe necessity of monitoring luteal endocrine functions in in vitro fertilization- embryo transfer (IVF-ET) remains uncertain. Specifically, the significance of luteal phase estradiol (E2) levels is a matter of debate in current literature.ObjectiveTo assess the impact of luteal phase (day 11 after HCG trigger) estradiol levels on IVF-ET outcomes.DesignTwelve thousand five hundred and thirty-five (n = 12,535) IVF-ET cycles performed in our center between 2015 and 2021 were divided into 5 groups based on the middle and late luteal phase serum E2 (MllPSE2) level percentiles as follows: Group A &lt; 50 pg/mL (N=500), group B 50 pg/mL≤E2&lt;150 pg/mL (N=2545), group C 150 pg/mL≤E2&lt;250 pg/mL (N=1327), group D 250 pg/mL≤E2&lt;500 pg/mL (N=925), group E E2≥500 pg/mL (n=668). The clinical pregnancy rates, abortion rates, and live birth rates of each group were compared. Binary logistic regression analysis was carried out to assess the potential impact of MllPSE2 on the live birth rate (LBR).ResultsNo significant differences were found in various parameters when comparing the five groups. The level of MllPSE2 showed no significant difference between the pregnant group and the non-pregnant group. The binary logistic regression analysis model demonstrated that MllPSE2 was not significantly related to LBR.ConclusionThe influence of E2 during the peri-implantation period (day 11) on clinical outcome in IVF-ET is not affected, even if E2&lt;50 pg/mL. It is speculated that ovarian-derived E2 in MllPSE2 is not deemed necessary for endometrial receptivity. Although caution is warranted due to the retrospective nature of the analysis and the potential for unmeasured confounding, it is argued that the need for luteal E2 monitoring in IVF-ET may be of questionable value.
Ultrasonographic predictors of thyroid cancer in Bethesda III and IV thyroid nodules
Authors: Alyusuf Ebtihal Y. , Alhmayin Lama , Albasri Eman , Enani Jawaher , Altuwaijri Hessa , Alsomali Nora , Arafah Maria A. , Alyusuf Zahra , Jammah Anwar A. , Ekhzaimy Aishah A. , Alzahrani Ali S. 
Published: February 2024

BackgroundBethesda III and IV thyroid nodules continue to be difficult to manage. Although molecular testing may assist in decision-making, it is expensive, not widely available, and not without pitfalls. The objective of this study is to assess whether certain thyroid ultrasonographic features may predict the risk of thyroid cancer in patients with Bethesda III and IV thyroid nodules and be used as additional decision-making tools to complement cytopathological results in deciding on diagnostic thyroidectomy.MethodsWe retrospectively evaluated the ultrasonographic features of Bethesda categories III and IV thyroid nodules in patients who underwent subsequent thyroidectomy. We used the final histopathological examination of the surgical specimens as the gold-standard test and analyzed individual preoperative ultrasonographic features as predictors of malignancy.ResultsOf the 278 patients who were diagnosed with Bethesda III and IV thyroid nodules on fine needle aspiration cytology (FNAC), 111 (39.9%) had thyroid cancer, and 167 (59.9%) exhibited benign nodules. The malignancy rate was higher in patients with Bethesda IV nodules (28/50, 56%) than those with Bethesda III nodules (83/228, 36.4%; p=0.016). In univariate analysis, hypoechogenicity (55.6% in malignant vs. 35.3% in benign, p=0.006) and calcifications (54.5 in malignant vs. 35.4% in benign, p=0.008) were significantly different between the benign and malignant pathology groups, whereas the size of the dominant nodule, number of nodules, irregular borders, taller-than-wide shape, and the presence of lymph nodes were comparable between the two groups. These two ultrasonographic features (hypoechogenicity and calcifications) remained significantly associated with the risk of malignancy in multivariate logistic regression analysis (for hypoechogenicity, p=0.014, odds ratio: 2.1, 95% CI:1.0–3.7 and for calcifications, p=0.019, odds ratio: 1.98, 95% CI:1.12–3.50). The sensitivity, specificity, positive and negative predictive values, and accuracy were 31.5%, 83%, 55.6%,64.7%, and 62.6%, for hypoechogenicity, respectively and 32.4%, 82%, 54.5%, 67.8%, and 62%, for calcification, respectively.ConclusionsHypoechogenicity and calcifications in Bethesda III and IV thyroid nodules are strong predictors of thyroid cancer and associated with a two-fold increased risk of malignancy.
Course of COVID-19 infection in patients with congenital adrenal hyperplasia
Authors: Javaid Rida , Sinaii Ninet , Kollender Sarah , Desai Jay , Moon Amy , Merke Deborah P. 
Published: February 2024

ContextPatients with primary adrenal insufficiency due to congenital adrenal hyperplasia (CAH) are at risk for adrenal crisis during infectious illnesses. Increased risk of infection including COVID-19 has been variably reported.ObjectiveTo evaluate COVID-19 illness outcomes and stress dose practices in a large cohort of patients with CAH during the first two years of the pandemic and compare observations of COVID-19 infection in patients with CAH to the general USA population.MethodsBetween March 2020 and November 2022, patients with CAH followed at the National Institutes of Health Clinical Center were queried about COVID-19 infection during their routine visits. Cases of COVID-19 were compared to controls. COVID-19 infection rates and symptoms were compared to general USA population data from the Centers for Disease Control and Prevention.ResultsOf 168 patient visits, there were 54 (32%) cases of COVID-19 infection, and 15 (28%) were pediatric. Overall an association was found between acquiring COVID-19 and obesity (p=0.018), and adults acquiring COVID-19 were on lower doses of fludrocortisone (p=0.008). Fewer cases of COVID-19 infection were reported in those receiving hydrocortisone or modified-release hydrocortisone compared to longer acting glucocorticoids (p=0.0018). In our CAH population, the pattern of COVID-19 infection rates and COVID-related symptomatology were similar to those observed in the general USA population. Most patients with the presumed alpha variant reported anosmia and ageusia, while gastrointestinal symptoms were commonly reported during the delta and omicron waves. Stress dosing occurred in 30/54 cases, and 7 received parenteral hydrocortisone. Two hospitalizations occurred; one pediatric and one adult, both with co-morbidities. There were 5 emergency room visits and no reported deaths.ConclusionPatients with CAH with close follow-up do not appear to be at increased risk of acquiring COVID-19 or to have a more severe course of COVID-19 compared to the general USA population. Obesity may increase risk of acquiring COVID-19 in patients with CAH, and overall infection risk may be lower in those receiving short-acting and circadian glucocorticoid replacement therapy. Established age-appropriate guidelines for stress dosing during infectious illnesses should be used for patients with CAH and COVID-19. COVID-19 specific guidelines are not indicated. Clinical Trial Registration: ClinicalTrials.gov, identifier NCT00250159.
COVID-19 booster enhances IgG mediated viral neutralization by human milk in vitro
Authors: Valcarce Vivian , Stafford Lauren Stewart , Neu Josef , Parker Leslie , Vicuna Valeria , Cross Tyler , D'Agati Olivia , Diakite Sisse , Haley Addison , Feigenbaum Jake , Al Mahmoud Mahmoud Y. , Visvalingam Anjali , Cacho Nicole , Kosik Ivan , Yewdell Jonathan W. , Larkin Joseph 
Published: February 2024

BackgroundFacilitated by the inability to vaccinate, and an immature immune system, COVID-19 remains a leading cause of death among children. Vaccinated lactating mothers produce specific SARS-CoV-2 antibodies in their milk, capable of neutralizing the virus in vitro. Our objective for this study is to assess the effect of COVID-19 booster dose on SARS-CoV-2 antibody concentration and viral neutralization in milk, plasma, and infant stool.MethodsThirty-nine mothers and 25 infants were enrolled from December 2020 to May 2022. Milk, maternal plasma, and infants' stool were collected at various time-points up to 12 months following mRNA COVID-19 vaccination. A subgroup of 14 mothers received a booster dose. SARS-CoV-2 antibody levels and their neutralization capacities were assessed.ResultsBooster vaccination led to significantly higher IgG levels within human milk and breastfed infants' stool. In vitro neutralization of VSV-gfp-SARS-CoV-2-S-gp, a laboratory safe SARS-CoV-2 like pseudovirus, improved following the booster, with a 90% increase in plasma neutralization and a 60% increase in milk neutralization. We found that post-booster neutralization by human milk was highly correlated to SARS-CoV-2 IgG level. In support of our correlation result, Protein G column depletion of IgG in milk yielded a significant reduction in viral neutralization (p = 0.04).DiscussionThe substantial increase in neutralizing IgG levels in milk and breastfed infants' stool post-booster, coupled with the decrease in milk neutralization capabilities upon IgG depletion, underscores the efficacy of booster doses in augmenting the immune response against SARS-CoV-2 in human milk.