bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sex difference in the age-related decline of global longitudinal strain of left ventricle
Authors: Lee Kyung-Yeon , Kim Hack-Lyoung , Kim Kyung-Jin 
Published: October 2023

AbstractGlobal longitudinal strain (GLS) is a valuable indicator of subclinical myocardial dysfunction. Whether the effect of aging on subclinical left ventricular dysfunction is sex-specific is not well documented. This study aimed to identify age-related changes in GLS according to sex in patients with a normal left ventricular ejection fraction (LVEF). In this cross-sectional, single-center cohort study in Korea, participants who underwent GLS measurement using 2D speckle-tracking echocardiography were retrospectively reviewed, and participants with normal LVEF (≥ 55%) without documented cardiovascular disease were included. Reduced GLS was defined as absolute values below 18%. Of 682 study participants (mean age, 58; female, 51.5%), 209 (30.6%) had reduced GLS. Females with reduced GLS were older than those with normal GLS (68 vs. 58 years, P < 0.001); with no difference of age in males (55 vs. 57 years; P = 0.265). Univariate analysis showed age to correlate significantly with reduced GLS only in female (r =  − 0.364; P < 0.001). In multivariable analysis, female > 66 years old had significantly higher risk of reduced GLS (Odds ratio 2.66; 95% CI 1.22–5.76; P = 0.014). In participants with normal LVEF, GLS decreased with age in females but not in males. Particularly, females aged 66 years and older had a significantly higher risk of reduced GLS. These findings suggest that GLS could be a valuable parameter for assessing subclinical cardiac dysfunction, especially in older females.
Association of gait and cognition after surgery in patients with idiopathic normal pressure hydrocephalus
Authors: Ishikawa Masatsune , Mori Etsuro 
Published: October 2023

AbstractIdiopathic normal pressure hydrocephalus (iNPH) is a treatable disease in older adults. The association between gait and cognition has recently become a topic of interest. Sequential changes in this association were investigated in patients with iNPH using a newly developed statistical method. Data were extracted from the SINPHONI-2 multicenter study on iNPH. Fifty patients who underwent shunt surgery were included in this study. Gait and cognition were assessed using the Timed Up and Go (TUG) and Mini-Mental State Examination (MMSE) tests. In addition to the MMSE total score, changes in the sub-item scores were examined. The ordinal sub-items of the MMSE are usually treated as continuous or categorical; however, both are unsuitable. An ordinal smoothing penalty with a generalized additive model enables precise statistical inference of ordinal and binary predictors. The TUG time improved significantly at 3, 6, and 12 months after surgery. The MMSE total scores increased without statistical significance. Preoperatively, there was no association between TUG time and MMSE sub-items. At 3 months, the “Registration,” ”3-step command,” “Read,” and “Copy” sub-items were statistically significant. The number of significant sub-items increased after 12 months. Thus, the association between gait and cognition gradually increased after surgery in patients with iNPH.
Effect of couple-based health education on male-partners knowledge and attitude towards maternity waiting homes in rural Ethiopia: a cluster-randomized trial
Authors: Yarinbab Teklemariam Ergat , Gesesew Hailay Abrha , Harrison Margo Shawn , Belachew Tefera 
Published: October 2023

AbstractThis cluster-randomized controlled trial examined the effect of couple-based health education on male partners’ knowledge and attitude towards maternity waiting homes (MWH) in rural Ethiopia. Sixteen clusters and 320 couples were randomly assigned to intervention group (receiving group health education, home visits and print health messages alongside usual care) or control group (receiving usual care). The Chi-square test was used to estimate statistical differences, and the difference-in-differences model was used to estimate the effect of the intervention. The generalized linear regression model was used to determine the odds of outcomes between the groups. Statistical significance was set at p < 0.05, with a 95% CI. There were no significant differences in baseline characteristics between the control and intervention groups. The net effect of the intervention on improving knowledge about MWHs, and attitude towards MWHs were 35.6% and 36.2%, respectively. The participants in the intervention group were 5.5 times more likely to have good knowledge about MWH (AOR 5.55, 95% CI 3.37–9.14) and 5.6 times more likely to have a favorable attitude towards MWH (AOR 5.61, 95% CI 3.45–9.10) compared to their counterparts. Health education provided to couples significantly improved male partners’ knowledge and attitude towards MWHs in rural Ethiopia.Trial registration: ClinicalTrials.gov Identifier: NCT05015023.
Initial skin necrosis presentation at emergency room was associated with fulminant clinical course and mortality in patients with Vibrio necrotizing fasciitis
Authors: Hsiao Chun-Yuan , Huang Tsung-Yu , Teng Li-Yun , Chen Hung-Yen , Hsiao Cheng-Ting , Tsai Yao-Hung , Kuo Shu-Fang 
Published: October 2023

AbstractNecrotizing fasciitis (NF) is a life-threatening infection. Skin necrosis is an important skin sign of NF. The purposes of this study was to investigate the initial skin conditions of Vibrio NF patients between emergency room (ER) to preoperative status, to compare the clinical and laboratory risk indicators of the skin necrosis group and non-skin necrosis group when they arrived at ER, and to evaluate whether initial cutaneous necrosis related to fulminant course and higher fatalities. From 2015 to 2019, seventy-two Vibrio NF patients with surgical confirmation were enrolled. We identified 25 patients for inclusion in the skin necrosis group and 47 patients for inclusion in the non-skin necrosis group due to the appearance of skin lesion at ER. Seven patients died, resulting in a mortality rate of 9.7%. Six patients of skin necrosis group and one patient of non-skin necrosis group died, which revealed the skin necrosis group had a significantly higher mortality rate than the non-skin necrosis group. All the patients in the skin necrosis group and 30 patients of non-skin necrosis group developed serous or hemorrhagic bullous lesions before operation (p = 0.0003). The skin necrosis group had a significantly higher incidence of APACHE score, postoperative intubation, Intensive care unit stay, septic shock, leukopenia, higher counts of banded leukocytes, elevated C-reactive protein (CRP), and lower serum albumin level. Vibrio NF patients presenting skin necrosis at ER were significantly associated with fulminant clinical courses and higher mortality. Physicians should alert the appearance of skin necrosis at ER to early suspect NF and treat aggressively by those clinical and laboratory risk indicators, such as elevated APACHE score, shock, leukopenia, higher banded leukocytes, elevated CRP, and hypoalbuminia.
Comprehensive analyses identify potential biomarkers for encephalitis in HIV infection
Authors: Wang Shitao , Ding Xiangqian , Li Zongyou , Rao Feng , Xu Hui , Lu Jinghong , Ma Xuelu , Zhang Mengen , Xie Zhenrong 
Published: October 2023

AbstractHuman immunodeficiency virus encephalitis (HIVE) is a severe neurological complication after HIV infection. Evidence shows that genetic factors play an important role in HIVE. The aim of the present study was to identify new potential therapeutic targets for HIVE. Differentially expressed gene (DEG), functional annotation and pathway, and protein–protein interaction analyses were performed to identify the hub genes associated with HIVE. Gene co-expression analysis was carried out to confirm the association between the hub genes and HIVE. Finally, the role of the hub genes in HIVE therapy was evaluated by conducting drug–gene interaction analysis. A total of 20 overlapping DEGs closely related to HIVE were identified. Functional annotation and pathway enrichment analysis indicated that the markedly enriched DEG terms included ion transport, type II interferon signaling, and synaptic signaling. Moreover, protein–protein interaction analysis revealed that 10 key HIVE-related genes were hub genes, including SCN8A, CDK5R2, GRM5, SCN2B, IFI44L, STAT1, SLC17A7, ISG15, FGF12, and FGF13. Furthermore, six hub genes were co-expressed with HIVE-associated host genes in human brain tissue. Finally, three hub genes (STAT1, ISG15, and SCN2B) interacted with several inflammation-associated drugs. These findings suggested that SCN8A, CDK5R2, GRM5, SCN2B, IFI44L, STAT1, SLC17A7, ISG15, FGF12, and FGF13 may be new targets for diagnosis and therapy of HIVE.
“Why Are You Meditating? You Can Just Pray”: A Focus Group Study With Hispanic/LatinaSpeech-Language Pathology Graduate Students
Authors: Medina Angela M. , Mead Jean S. 
Published: October 2023

Purpose:
The purpose of this exploratory study was to investigate the perceptions of mindfulness held by a small sample of graduate Hispanic/Latina speech-language pathology (SLP) students.

Method:
Seven second-year graduate SLP students who identified as Hispanic/Latina were included in this study. Participants completed a survey and participated in a 60-min focus group session. Survey data were analyzed using descriptive statistics, while focus group data underwent thematic analysis.

Results:
Thematic analysis of the focus group data gave rise to three major themes: “perceptions of mindfulness,” “cultural parallels,” and “familial considerations,” which was composed of two subthemes: “openness about practice” and “tools to facilitate family understanding.”

Conclusion:
Participants in this study discussed the benefits of mindfulness and their willingness to practice; however, stigmatizing beliefs and lack of education about mindfulness within their cultural communities need to be addressed.
Investigation of transmission characteristic for harmonic magnetic gears considering dynamic eccentricity using magnetic equivalent circuit
Authors: Li Bingchu , Shi Jiahao , Wang Shuangyuan , Liu Chengliang 
Published: October 2023

AbstractHarmonic magnetic gears (HMGs) have the advantage of lubrication‐free, high speed ratio and high torque density, which make it an attractive solution for safety critical applications. Due to eccentricity caused by machining and assembly, HMG suffers from dynamic eccentricity (DE) in operation, however, its effect on HMG performance is still unknown. Transmission characteristic of HMG under DE is studied. First, a magnetic equivalent circuit (MEC) model of HMG is proposed to build the magnetic coupling torque analytically, and the geometry of air gap is analysed parametrically to derive its equivalent reluctances. Flux density and coupling torque can be acquired by solving MEC equations. The accuracy of the MEC model is verified by finite element method. To study the transmission characteristic, an electromechanical coupling simulation framework for HMG is constructed, motion trajectories of rotors are investigated in case of DE, the output torque in locked‐rotor condition and speed response in continuous operation can be derived by simulation. It is found that torque ripples that have the same frequency with input rotor are induced by DE; the results are then verified in the experiment. This paper provides a theoretical guidance for the design and condition monitoring of HMG.
Physical Activity, Inactivity and Sleep in Individuals with
Hypertrophic Cardiomyopathy
Authors: Charman Sarah J , Blain Alasdair P , Okwose Nduka C , Fuller Amy S , Alyahya Alaa I , Hallsworth Kate , Eggett Christopher , Luke Peter , Bailey Kristian , MacGowan Guy A , Jakovljevic Djordje G 
Published: October 2023

AbstractPhysical activity presents an important cornerstone in the management and care of
individuals with hypertrophic cardiomyopathy (HCM). Twenty-one individuals with
HCM (age: 52±15 years old, body mass index (BMI):
30±7 kg/m2) completed 7-day monitoring
using wrist-worn triaxial accelerometers (GENEActiv, ActivInsights Ltd, UK) and
were compared to age and sex-matched healthy controls (age: 51±14 years
old, BMI: 25±4 kg/m2). For individuals with
HCM, clinical parameters (left atrial diameter and volume, peak oxygen
consumption, NTproBNP and Minnesota Living with Heart Failure (MLHF)) were
correlated with accelerometry. After adjusting for BMI, individuals with HCM
spent less time in moderate-vigorous physical activity (MVPA) (86
(55–138) vs. 140 (121–149) minutes/day,
p<0.05) compared to healthy controls. Individuals with HCM
engaged in fewer MVPA-5 min (6 (2–15) vs. 27 (23–37)
minutes/day, p<0.01) and MVPA-10 min bouts (9
(0–19) vs. 35 (17–54) minutes/day,
p<0.01) versus healthy controls. For HCM only, peak oxygen
consumption was correlated with MVPA (r=0.60,
p<0.01) and MVPA-5 min bouts (r=0.47,
p<0.05). MLHF score was correlated with sleep duration
(r=0.45, p<0.05). Individuals with HCM should
be encouraged to engage in moderate-intensity physical activity bouts and reduce
prolonged periods of inactivity in order to potentially improve exercise
tolerance and reduce disease burden.
Thermostable Insensitive Energetic Materials Based on a Triazolopyridine Fused Framework with Alternating Nitro and Amine Groups
Authors: Zhang Qinghua , Ran You , Xia Honglei , Song Siwei , Wang Kangcai 
Published: October 2023

AbstractIn this work, we designed and synthesized a series of novel triazolopyridine fused-ring compounds with alternating nitro and amine groups. Three compounds showed remarkable thermal stability at 256, 310, and 294 °C, respectively, and a low mechanical sensitivity [impact sensitivity (IS) = 40 J, friction sensitivity (FS) = 324 N; IS = 35 J, FS = 240 N; and IS > 40 J, FS = 324 N, respectively]. Significantly, two of these compounds exhibited a better detonation performance [detonation velocity (D) = 8200 and 8335 m s–1, Detonation pressure (P) = 25.6 and 27.2 GPa, respectively] than the widely used heat-resistant explosive hexanitrostilbene (HNS; D = 7612 m s–1, P = 24.3 GPa). Additionally, a nitramine derivative displayed a detonation performance (D = 8569 m s–1, P = 31.3 GPa) similar to that of the high-energy explosive RDX. The superior properties of the materials were further confirmed by X-ray diffraction analysis and by several theoretical calculations (ESP, LOL–π, Hirshfeld surfaces, RDG, and NCI analyses). These results indicated that the three compounds might be potential candidates for use as heat-resistant energetic materials.
Homoeopathic Pathogenetic Trial of Catharanthus roseus: A Multicentric, Double-Blind, Randomized, Placebo-Controlled Trial
Authors: Mehra Pritha , Debata Lipipushpa , Sahoo Amulya R. , Rajakumar B. S. J. , Mahajan Ashish , Arya Bhopal S. 
Published: October 2023

AbstractMedicinal plants have a long history of usage in traditional medicine, and Catharanthus roseus L. (G.) Don is one such plant. However, to understand its homoeopathic therapeutic effect, it was important to find the pathogenetic powers by conducting a drug proving trial. To elicit the pathogenetic response of C. roseus in homoeopathic potencies on healthy human provers, a multicenter, randomized, double-blind, placebo-controlled trial was conducted at four centers under the Central Council for Research in Homoeopathy. The proving trial involved 60 relatively healthy provers. All provers were given placebo in the first phase. After randomization, 40 provers in the intervention group were given C. roseus in 6C, 12C, 30C, and 200C potencies in four phases. The control group of 20 provers were administered unmedicated globules in all the phases. A maximum of 12 doses divided into 4 doses/day for 3 days were administered in all phases of the trial. The symptoms and signs manifested during the trial were noted down by the provers, elaborated by the proving masters, and the data were finally processed at the proving-cum-data processing cell of the Council. Among the 40 provers of the verum group, only 15 provers manifested 22 pathogenetic and 10 placebo symptoms, whereas 30 symptoms were reported by 12 provers in the control group. The symptoms have been manifested predominantly in 200C potency. The pathogenetic response elicited during this trial expands the scope of the use of C. roseus and needs to be further validated by a clinical verification study.
Performance analysis of a novel flat lay-type synthetic jet pump with Y-shaped jet chamber
Authors: He Lipeng , Hu Renhui , Wang Chensheng , Hu Dianbin , Li Xiaotao , Cheng Guangming 
Published: October 2023

Recently, synthetic jet pumps have been expected to be used in electronic heat dissipation devices due to the vortex suction phenomenon for transporting fluids. Aiming to improve the delivery ability of the jet pump to output fluid continuously, a novel flat lay-type synthetic jet pump (FLTSJP) with a Y-shaped jet chamber is proposed in this paper. Based on the synthetic jet effect, the pump chamber continuously outputs fluid in one cycle. The output performance of FLTSJP is theoretically analyzed to be affected by the outlet cone angle. The one-cycle flow mechanism of the fluid in the Y-shaped jet chamber is simulated. FLTSJP is manufactured, and a test system is built. Experiments show that the Y-shaped jet chamber effectively improves the output performance. The optimum flow rate and outlet pressure were both reached at 160 V and 40 Hz, which were 20.63 ml/min and 333.43 Pa, respectively. This FLTSJP effectively improves the output performance of synthetic jet pumps and provides a new research concept of water-cooled devices for electronic heat dissipation.
Conceptual transfer
Authors: Jarvis Scott 
Published: October 2023

AbstractThis article provides updated perspectives on research related to conceptual transfer, which is defined as crosslinguistic influence arising from language-specific concepts and patterns of conceptualization. I discuss the historical roots of conceptual transfer, its relationship to linguistic relativity and thinking for speaking, its core assumptions, and its current scope of inquiry. While discussing its scope of inquiry, I review some of the key findings in this area of research as well as some of the recent studies that have expanded its scope. I conclude with a summary of five important points that can be drawn from the existing research on conceptual transfer, and I offer suggestions for future directions.
Strong maximum a posteriori estimation in Banach spaces with Gaussian priors
Authors: Lambley Hefin 
Published: October 2023

Abstract
This article shows that a large class of posterior measures that are absolutely continuous with respect to a Gaussian prior have strong maximum a posteriori estimators in the sense of Dashti et al (2013 Inverse Problems
29 095017). This result holds in any separable Banach space and applies in particular to nonparametric Bayesian inverse problems with additive noise. When applied to Bayesian inverse problems, this significantly extends existing results on maximum a posteriori estimators by relaxing the conditions on the log-likelihood and on the space in which the inverse problem is set.
A first-principles study of the electronic, vibrational, and optical properties of planar SiC quantum dots
Authors: Jindal Rupali , Roondhe Vaishali , Shukla Alok 
Published: October 2023

Abstract
With the reported synthesis of a fully planar 2D silicon carbide (SiC) allotrope, the possibilities of its technological applications are enormous. Recently, several authors have computationally studied the structures and electronic properties of a variety of novel infinite periodic SiC monolayers, in addition to the honeycomb one. In this work, we perform a systematic first-principles investigation of the geometry, electronic structure, vibrational, and optical absorption spectra of several finite, but, fully planar structures of SiC, i.e. 0D quantum dots (QDs). The sizes of the studied structures are in the 1.20–2.28 nm range, with their computed HOMO(H)-LUMO(L) gaps ranging from 0.66 eV to 4.09 eV, i.e. from the IR to the UV region of the spectrum. The H-L gaps in the SiC QDs are larger as compared to the band gaps of the corresponding monolayers, confirming the quantum confinement effects. In spite of covalent bonding in the QDs, Mulliken charge analysis reveals that Si atoms exhibit positive charges, whereas the C atoms acquire negative charges, due to the different electron affinities of the two atoms. Furthermore, a strong structure property relationship is observed with fingerprints both in the vibrational and optical spectra. The wide range of H-L gaps in different SiC QDs makes them well-suited for applications in fields such as photocatalysis, light-emitting diodes, and solar cells.
Remaining useful life prediction of rolling bearings based on TCN-MSA
Authors: Jiang Guangjun , Duan Zhengwei , Zhao Qi , Li Dezhi , Luan Yu 
Published: October 2023

Abstract
As a pivotal element within the drive system of mechanical equipment, the remaining useful life (RUL) of rolling bearings not only dictates the lifespan of the equipment’s drive system but also the overall machine. An inaccurate prediction of the RUL of rolling bearings could hinder the formulation of maintenance strategies and lead to a chain of failures stemming from bearing malfunction, culminating in potentially catastrophic accidents. This paper designs a novel temporal convolutional network-multi-head self-attention (TCN-MSA) model for predicting the RUL of rolling bearings. This model considers the intricate non-linearity and complexity of mechanical equipment systems. It captures long-term dependencies using the causally inflated convolutional structure within the temporal convolutional network (TCN) and simultaneously extracts features from the frequency domain signal. Subsequently, by employing the multi-head self-attention (MSA) mechanism, the model discerns the significance of different features throughout the degradation process of rolling bearings by analyzing global information. The final prediction for rolling bearings’ RUL has been successfully attained. To underline the excellence of the method presented in this paper, a comparative analysis was performed with existing methods, such as convolutional neural network, gate recurrent unit, and TCN. The results highlight that the model designed in this paper surpasses other existing methods in predicting the RUL of rolling bearings, demonstrating superior prediction accuracy and robust generalization capability.