bluuebunny/crossref_metadata_2025_split huggingface dataset:
KINERJA PENGELOLAAN DAS PAGUYAMAN BERDASARKAN KONDISI FISIKA DAN KIMIA AIR
Authors: Lahili Rahmanto , Lihawa Fitriyane , Dunggio Iswan 
Published: November 2023

ABSTRAK Aktivitas penambangan oleh masyarakat di sempadan Sungai Paguyaman, menyebabkan pencemaran di perairan sungai. Dampak langsung dapat dilihat pada kualitas perairannya. Tujuan penelitian ini adalah untuk menganalisis kualitas air Sungai Paguyaman pada areal penambangan batuan Desa Motoduto Kecamatan Boliyohuto. Penelitian ini dilakukan pada tahun 2022 di Sungai Paguyaman. Pengambilan sampel air di dilakukan di tiga tempat yaitu sebelum lokasi tambang sebagai kontrol, di tapak kegiatan tambang liar saat beraktivitas dan setelah lokasi pertambangan. Paremeter kualitas air meliputi parameter kecerahan, pH, dan Dissolved Oxygen (DO). total dissolved solid (TDS), Total Suspended Solid (TSS), suhu dan ammonia, Biologycal Oxygen Demand (BOD) dan Chemical Oxygen Demand (COD). Hasil pengukuran akan ditampilkan dalam bentuk grafik dan dibahas seacara deskriptif dengan merujuk pada baku mutu PP Nomor 22 tahun 2021 (Lampiran VI). Hasil analisis laboratorium menunjukkan bahwa parameter TSS dan Surfactan melewati baku mutu kualitas air untuk Kelas II. Konsentrasi TSS di lokasi control sebesar 98 mg/l dan Surfactan 0,009 mg/l. Konsentrasi TSS di sekitar lokasi tambang sebesar 119 mg/l dan Surfactan 0,02 mg/l. Konsentrasi TSS setelah lokasi tambang adalah 148 mg/l dan Surfactan sebesar 0,021 mg/l. Baku mutu TSS untuk air sungai Kelas II sebesar 50 mg/l dan Surfactan sebesar 0,001 mg/l.ABSTRACT Rock mining activities on the Paguyaman River border can cause river water pollution. The purpose of this study was to analyze the water quality of the Paguyaman River around the rock mining area of Motoduto Village, Boliyohuto District. Water sampling was carried out at three locations, namely before the mine site as a control, at the rock mining activity site and after the mining site. Water quality parameters include brightness, pH, and Dissolved Oxygen (DO) parameters. total dissolved solid (TDS), Total Suspended Solid (TSS), temperature and ammonia, Biological Oxygen Demand (BOD) and Chemical Oxygen Demand (COD). The measurement results will be displayed in graphic form and analyzed descriptively by referring to the PP No. 22 of 2021 quality standard (Appendix VI). The results of the laboratory analysis showed that the TSS and Surfactant parameters passed the water quality standard for Class II. The concentration of TSS at the control location was 98 mg/l and surfactant 0.009 mg/l. The concentration of TSS around the mine site is 119 mg/l and Surfactan is 0.02 mg/l. The concentration of TSS after the mine site is 148 mg/l and Surfactan is 0.021 mg/l. The TSS quality standard for Class II river water is 50 mg/l and Surfactant is 0.001 mg/l.
STRATEGI KEBERLANJUTAN AGROFORESTRY DI DESA ULUSADDANG KABUPATEN PINRANG
Authors: Ariandi Rahmat , Mukti Jauhar 
Published: November 2023

ABSTRAKSeiring dengan perluasan luas lahan yang rentan, timbul berbagai isu sosial karena kerusakan sumber daya hutan yang merupakan penopang kehidupan. Dalam upaya menggabungkan manfaat ekonomi, ekologi, dan sosial, model agroforestri muncul sebagai cara untuk optimalisasi pemanfaatan lahan, menggabungkan berbagai tanaman kayu, tanaman pertanian, peternakan, dan unsur lainnya pada satu area. Tujuan dari penelitian ini adalah merumuskan alternatif strategi untuk menjaga keberlanjutan agroforestri di Kabupaten Pinrang, khususnya di Desa Ulusaddang. Riset ini berlangsung di Desa Ulusaddang, melibatkan KTH Sipatuo sebagai subjek penelitian. Langkah pertama mencakup analisis tingkat keberlanjutan agroforestri menggunakan pendekatan RAP-AFS dan teknik analisis Multidimensional Scaling (MDS). Selanjutnya, dilakukan perumusan strategi alternatif untuk menjaga keberlanjutan agroforestri dengan memanfaatkan metode AHP melalui perangkat lunak Expert Choice 11. Hasil penelitian menunjukkan bahwa keberlanjutan agroforestri di KTH Sipatuo, Desa Ulusaddang, sebagian besar tergolong dalam kategori kurang berkelanjutan dengan indeks nilai 48,28. Strategi yang diutamakan dalam menjaga keberlanjutan agroforestri di Desa Ulusaddang adalah kemitraan melalui skema program Forest IV, memiliki bobot prioritas 0,610 (61%). Sedangkan, strategi kedua adalah subsidi modal dengan bobot 0,390 (39%).Kata Kunci: Agroforestri, Multidimensonal Scalling (MDS), RAP-AFSABSTRACTAlongside the expanding vulnerable land area, various social issues arise due to the degradation of forest resources, which are the foundation of life. In an effort to integrate economic, ecological, and social benefits, the agroforestry model emerges as a way to optimize land utilization by combining various wood plants, crops, livestock, and other elements in a single area. The aim of this research is to formulate alternative strategies for maintaining agroforestry sustainability in Pinrang Regency, particularly in Ulusaddang Village. This study took place in Ulusaddang Village, involving KTH Sipatuo as the research subject. The initial steps include analyzing the sustainability level of agroforestry using the RAP-AFS approach and Multidimensional Scaling (MDS) analysis technique. Subsequently, the formulation of alternative strategies for sustaining agroforestry is conducted using the AHP method through Expert Choice 11 software. The research findings indicate that the sustainability of agroforestry in KTH Sipatuo, Ulusaddang Village, mostly falls under the less sustainable category with an index value of 48.28. The prioritized strategy for maintaining agroforestry sustainability in Ulusaddang Village is partnership through the Forest IV program scheme, with a priority weight of 0.610 (61%). Meanwhile, the second strategy is capital subsidy with a weight of 0.390 (39%). Keywords: Agroforestry, Multidimensonal Scalling (MDS), RAP-AFS
ANALISIS KOMPARATIF SINKRONIS BAHASA SUNDA DENGAN BAHASA JAWA DIALEK DESA PANJALIN KIDUL KABUPATEN MAJALENGKA (KAJIAN LINGUISTIK HISTORIS KOMPARATIF)
Authors: Rahmawati Novia , Ratnawati  
Published: November 2023

Penelitian ini bertujuan untuk mengetahui kekerabatan bahasa Sunda dengan bahasa Jawa dialek Desa Panjalin Kidul. Metode penelitian yang digunakan adalah metode kualitatif deskriptif. Penyediaan data yang dilakukan menggunakan metode cakap dan simak. Instrumen yang digunakan dalam proses pengumpulan data adalah daftar kosa kata bahasa Sunda. Metode analisis data yang digunakan yaitu metode komparatif sinkronis. Penelitian ini dilakukan di Desa Panjalin Kidul, Kabupaten Majalengka, Provinsi Jawa Barat. Hasil penelitian ini menujukkan bahwa diperoleh 84 data yang berkerabat berdasarkan gejala variasi bunyi bahasa dari 160 kosa kata. Dengan 68 data variasi bunyi bahasa sinonim dan 16 data variasi bunyi bahasa homonim. Adapun tingkat kekerabatan bahasa Sunda dengan bahasa Jawa sebesar 80% dengan jangka kesalahan untuk menetapkan persentase kekerabatan yaitu 8,6. Oleh karena itu, dapat disimpulkan bahwa bahasa Sunda dengan bahasa Jawa dialek Desa Panjalin Kidul memiliki kekerabatan bahasa dengan persentase 80% dan memperlihatkan adanya daya tarik menarik antara kedua bahasa tersebut.
MODEL PEMBELAJARAN KOOPERATIF TEAM GAMES TOURNAMENT DAPAT MENINGKATKAN MOTIVASI PEMBELAJARAN BOLA BASKET DI KELAS X IPA 1 SMAN 1 CILIMUS
Authors: Muhamad Sidik Avip 
Published: November 2023

Avip Muhamad Sidik ( NIM: 182223126), Penelitian ini bertujuan untuk meningkatkan motivasi belajar siswa dalam pembelajaran bola basket SMAN 1 Cilimus melalui metode Team Game Tournament. Penelitian ini merupakan penelitian eksperimen yang dilaksanakan selama 3 pertemuan. populasi penelitian ini adalah peserta didik kelas X IPA 1 SMAN 1 Cilimus yang berjumlah 36 orang. Hasil penelitian menunjukkan bahwa metode Team Game Tournament sangat cocok diterapkan siswa kelas X IPA 1 SMAN 1 Cilimus. Karena dengan program Team Game Tournament peserta didik dapat meningkatkan motivasi dan semangat dalam pembelajaran bola basket. Kesimpulan bahwa Team Game Tournament dapat meningkatkan motivasi belajar siswa.
Kata kunci : Team Game Tournament, Bola basket
Pengaruh Intervensi Fisioterapi Konvensional terhadap Pemenuhan Activities of Daily Living (ADL) pada Pasien Hemiparese Dextra: Studi Kasus
Authors: Perdana Suryo Saputra , Putra Guntur Rusmana , Salam Muhamad Elfitra , Fitri Nabila Nur Afifah , Yusrianti Uslifah Izmarilda , Handayani Amelia Dwi 
Published: November 2023

Latar Belakang: Intracerebral haemorrhage (ICH) brainstem adalah kumpulan darah fokal yang berada di dalam batang otak. Penyebabnya meliputi hipertensi, malformasi vaskular dan tumor apoplexy. Manifestasi klinis yang muncul berupa kehilangan kesadaran, hemiparese, defisit sensori, ataksia, dan lainnya. Intervensi fisioterapi konvensional dapat diberikan untuk menunjang proses rehabilitasi pada pasien pasca stroke ICH brainstem. Tujuan dari penelitian ini adalah mengetahui pengaruh intervensi fisioterapi konvensional terhadap pemenuhan ADL pada pasien pasca stroke ICH brainstem. Metode: Studi kasus tunggal pada wanita 55 tahun dengan diagnosis hemiparese dextra et causa ICH brainstem. Intervensi fisioterapi konvensional berupa infrared radiationdan terapi latihan diberikan sebanyak 4 kali dalam 2 minggu. Evaluasi dilakukan sebanyak 2 kali dengan membandingkan skor pre dan post test. Hasil: Terjadi perubahan pada skala nyeri diam dengan NRS, kekuatan otot dengan MMT, dan pemenuhan ADL dengan Barthel Index. Namun, total skor risiko jatuh dengan Morse Fall Scale tidak berubah. Kesimpulan: Studi kasus ini menyimpulkan bahwa intervensi fisioterapi konvensional berpengaruh terhadap pemenuhan activities of daily living (ADL) pada pasien hemiparese dextra.
Active Stretching With Slow deep breathing Exercise pada Pembatik Menurunkan Keluhan Muskulosekeletal dan Peningkatan Produktivitas
Authors: Nahdliyyah Ade Irma , Ristiawati Ristiawati , Hermawan Agung 
Published: November 2023

Perkembangan industri batik di Pekalongan tidak hanya diindustri besar akan tetapi pada industri kecil menengah. Hal ini dipengaruhi adanya peningkatan permintaan pasar batik baik nasional maupun internasional. Dampak dari peningkatan tersebut menyebabkan beban kerja naik dan memunculakan masalah kesehatan jika tidak dilakukan preventif maupun promotif. Salah satu masalah yang muncul pada pekerja batik yaitu keluhan muskuloskeletal dan peningkatan beban fisiologi sehingga dapat menurunkan produktivitas pekerja. Upaya untuk meminimalisir problem tersebut ialah stretching dan slow deep breathing exercise. Penelitian ini bertujuan membantu menurunkan keluhan muskuloskeletal dan meningkatkan produktivitas pada pengrajin batik dengan pemberian latihan Active Stretchingdan slow deep breathing exercise. Penelitian ini berupa penelitian eksperimental, dengan menggunakan rancangan sama subjek (treatment by subject design). Jumlah subjek penelitan 24 orang.. Analisa data pada penelitian ini menggunakan uji paired sample t-test. Adanya penurunan secara signifikan pada keluhan muskuloskeletal dan peningkatan produktivitas pekerja batik pada sebelum diberikan intervensi (periode 1) dengan setelah intervensi ( periode 2). Latihan active stetching dan slow deep breathing dapat menurunkan keluhan musculoskeletal dan peningkatan produktivitas pada pekrja batik. Dibutuhkan waktu yang cukup lama dan spesifik pada pekerja batik untuk lebih detail dalam penelitian selanjutnya.
Bioregionalism to Realize the Utilization of Sustainable and Environmentally Friendly Tourism Space Based on Local Wisdom in Bali
Authors: Julianti Lis , Sugiantari Anak Agung Putu Wiwik , Saraswati Putu Sekarwangi 
Published: November 2023

This study aimed at formulating a new regulation model which is capable of integrating economical and ecological aspects in a bioregionalism concept for the utilization of tourism space based on local wisdom in Bali. Considering the Balinese tourism industry is vulnerable to the environmental damage, there should be a protection upon the sustainability of the tourism industry in a regulation arrangement which emphasizing on preservation aspect. Bioregionalism proposes an idea of self-sufficient, self-fulfilled, and economical sovereignty to fulfill all of the needs of the local people based on the existing natural sources and potency by synchronizing the local nature. It is an analytical descriptive study which was designed in 2 years with qualitative approach. The data collection was done through in-depth interview in which the informants were purposively selected. This study produced a regulation model of space utilization in tourism area based on bioregionalism to realize the sustainable and environmentally friendly Balinese development. This study becomes a new reference in environmentally sustainable development in tourism sector. Through bioregionalism concept, the negative impact of the activity involving the environmental, social and economic aspects can be revealed.
Assessment of Economic and Social Conditions of the Community: Before and After the Jagoi Babang State Cross Border Post, West Kalimantan, Indonesia
Authors: Siregar Rizki Abdillah H. , Nugroho Lucky 
Published: November 2023

This study aimed to determine the economic and social impact on the community of constructing the Jagoi Babang cross-border post (PLBN) in West Kalimantan, Indonesia. The method used in this study is a quantitative method, which uses questionnaires to the community in the Jagoi Babang sub-district to be able to answer the formulation of problems in this study, which include: (i) What was the economic condition of the Jagoi Babang community before the construction of PLBN?, (ii) What was the economic condition of the Jagoi Babang community at the time after the operation of the PLBN?, (iii) What was the social condition of the Jagoi Babang community before the construction of the PLBN?, (iv) What was the social condition of the Jagoi Babang community at the time of the operation of the PLBN?. Therefore, the data used in this study is primary data, and the statistical method in this study is a descriptive method. The results of this study are known: (i) the operation, of the Jagoi Babang PLBN has an impact on improving the economic indicators of the community around the PLBN; (ii) The operation of the Jagoi Babang PLBN has an impact on improving the social indicators of the community around the PLBN. The novelty of this research is related to the object of research, namely the economic and social impacts of the construction of cross-border posts (PLBN) which have not been studied much before.
Evidence of a conserved mammalian immunosuppression mechanism in Lutzomyia longipalpis upon infection with Leishmania
Authors: Telleria Erich Loza , Tinoco-Nunes Bruno , Forrest David M. , Di-Blasi Tatiana , Leštinová Tereza , Chang Kwang Poo , Volf Petr , Pitaluga André Nóbrega , Traub-Csekö Yara Maria 
Published: November 2023

IntroductionSand flies (Diptera: Phlebotominae) belonging to the Lutzomyia genus transmit Leishmania infantum parasites. To understand the complex interaction between the vector and the parasite, we have been investigating the sand fly immune responses during the Leishmania infection. Our previous studies showed that genes involved in the IMD, Toll, and Jak-STAT immunity pathways are regulated upon Leishmania and bacterial challenges. Nevertheless, the parasite can thrive in the vectors’ gut, indicating the existence of mechanisms capable of modulating the vector defenses, as was already seen in mammalian Leishmania infections.Methods, results, and discussionIn this study, we investigated the expression of Lutzomyia longipalpis genes involved in regulating the Toll pathway under parasitic infection. Leishmania infantum infection upregulated the expression of two L. longipalpis genes coding for the putative repressors cactus and protein tyrosine phosphatase SHP. These findings suggest that the parasite can modulate the vectors’ immune response. In mammalian infections, the Leishmania surface glycoprotein GP63 is one of the inducers of host immune depression, and one of the known effectors is SHP. In L. longipalpis we found a similar effect: a genetically modified strain of Leishmania amazonensis over-expressing the metalloprotease GP63 induced a higher expression of the sand fly SHP indicating that the L. longipalpis SHP and parasite GP63 increased expressions are connected. Immuno-stained microscopy of L. longipalpis LL5 embryonic cells cultured with Leishmania strains or parasite conditioned medium showed cells internalization of parasite GP63. A similar internalization of GP63 was observed in the sand fly gut tissue after feeding on parasites, parasite exosomes, or parasite conditioned medium, indicating that GP63 can travel through cells in vitro or in vivo. When the sand fly SHP gene was silenced by RNAi and females infected by L. infantum, parasite loads decreased in the early phase of infection as expected, although no significant differences were seen in late infections of the stomodeal valve.ConclusionsOur findings show the possible role of a pathway repressor involved in regulating the L. longipalpis immune response during Leishmania infections inside the insect. In addition, they point out a conserved immunosuppressive effect of GP63 between mammals and sand flies in the early stage of parasite infection.
Case report: Whole exome sequencing and genome-wide methylation profiling of Czech dysplasia in a Chinese pedigree
Authors: Zhao Mengfei , Zhang Runrun , Chang Cen , Jin Yehua , Xu Lingxia , Guo Shicheng , Schrodi Steven , He Yong , He Dongyi 
Published: November 2023

BackgroundCzech dysplasia is a rare skeletal disorder with symptomatology including platyspondyly, brachydactyly of the third and fourth toes, and early-onset progressive pseudorheumatoid arthritis. The disorder segregates in an autosomal dominant fashion. A specific missense mutation (R275C, c.823C &gt; T) in exon 13 of the COL2A1 gene has been identified in German and Japanese families.Case summaryWe present the case of a Chinese woman diagnosed with Czech dysplasia (proband) who carried a variant in the COL2A1 gene. Whole-exome sequencing (WES) identified the COL2A1 missense mutation (R275C, c.823C &gt; T) in close relatives of the proband who also exhibited the same disorder.ConclusionThis study is a thorough clinical and physiological description of Czech dysplasia in a Chinese patient.
A one-year pilot study comparing direct-infusion high resolution mass spectrometry based untargeted metabolomics to targeted diagnostic screening for inherited metabolic diseases
Authors: Willems Anke P. , van der Ham Maria , Schiebergen-Bronkhorst Birgit G. M. , van Aalderen Mirjam , de Barse Martina M. J. , De Gruyter Fini E. , van Hoek Ilja N. , Pras-Raves Mia L. , de Sain-van der Velden Monique G. M. , Prinsen Hubertus C. M. T. , Verhoeven-Duif Nanda M. , Jans Judith J. M. 
Published: November 2023

Background: Early diagnosis of inherited metabolic diseases (IMDs) is important because treatment may lead to reduced mortality and improved prognosis. Due to their diversity, it is a challenge to diagnose IMDs in time, effecting an emerging need for a comprehensive test to acquire an overview of metabolite status. Untargeted metabolomics has proven its clinical potential in diagnosing IMDs, but is not yet widely used in genetic metabolic laboratories.Methods: We assessed the potential role of plasma untargeted metabolomics in a clinical diagnostic setting by using direct infusion high resolution mass spectrometry (DI-HRMS) in parallel with traditional targeted metabolite assays. We compared quantitative data and qualitative performance of targeted versus untargeted metabolomics in patients suspected of an IMD (n = 793 samples) referred to our laboratory for 1 year. To compare results of both approaches, the untargeted data was limited to polar metabolites that were analyzed in targeted plasma assays. These include amino acid, (acyl)carnitine and creatine metabolites and are suitable for diagnosing IMDs across many of the disease groups described in the international classification of inherited metabolic disorders (ICIMD).Results: For the majority of metabolites, the concentrations as measured in targeted assays correlated strongly with the semi quantitative Z-scores determined with DI-HRMS. For 64/793 patients, targeted assays showed an abnormal metabolite profile possibly indicative of an IMD. In 55 of these patients, similar aberrations were found with DI-HRMS. The remaining 9 patients showed only marginally increased or decreased metabolite concentrations that, in retrospect, were most likely to be clinically irrelevant. Illustrating its potential, DI-HRMS detected additional patients with aberrant metabolites that were indicative of an IMD not detected by targeted plasma analysis, such as purine and pyrimidine disorders and a carnitine synthesis disorder.Conclusion: This one-year pilot study showed that DI-HRMS untargeted metabolomics can be used as a first-tier approach replacing targeted assays of amino acid, acylcarnitine and creatine metabolites with ample opportunities to expand. Using DI-HRMS untargeted metabolomics as a first-tier will open up possibilities to look for new biomarkers.
Evidence of antagonism in vitro and in vivo of extracts from Banisteriopsis laevifolia (A. Juss) B. Gates against the rice blast fungus
Authors: Simão Jorge Luiz Souza , Teodorico Matheus Santos de Souza , Silva Maria Ivanir de Sousa Cardoso , Coelho Carla Thaís Pereira , Bezerra Gustavo de Andrade , Arriel Elias Marina Teixeira , de Fillipi Marta Cristina Corsi , de Araújo Leila Garcês , Pasqualotto Severino Vanessa Gisele 
Published: November 2023

Rice blast is a common disease caused by Magnaporthe oryzae which affects rice production worldwide, including Brazil. To reduce the use of harmful pesticides, sustainable control options are necessary for managing rice blast. One possible option is to use plant extracts because they produce secondary metabolites capable of inhibiting the pathogen and controlling the disease. This study aimed to evaluate the potential of ethanolic extracts of leaves and flowers from Banisteriopsis laevifollia, a native Brazilian plant, to antagonise M. oryzae. In vitro antifungal activity assays were carried out, in which mycelium growth reduction, conidia germination, and appressorium formation of M. oryzae were evaluated. In addition, in vivo assay for suppression of leaf blast severity by extracts was done. We also explored the identification of secondary metabolites from ethanolic extracts of leaves and flowers by HPLC–HRMS. Results showed that both leaf and flower extracts inhibited mycelial growth in 21.72% and 30.49%, respectively, due to the inhibition of ergosterol production. Additionally, both extracts inhibited melanin production in the mycelium of M. oryzae by inhibiting tyrosine production. Both leaf and flower extracts significantly inhibited conidia germination and appressorium formation. Furthermore, rice leaves treated with the extracts suppressed by 18.17% and 18.97% leaf blast severity, with the 1.00 mg/mL concentration of flower extract and 0.75 mg/mL concentration of leaf extract, respectively, showing the most significant reduction of leaf blast. The extracts contain phenolic compounds, including 2,3,7,8-tetrahydroxy-chromeno-(5,4,3)-chromene-5,10-dione, 3-(4-hydroxyphenyl)-2-propenoic acid, 2-(3,4-dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol, 3,4′,5,7-tetrahydroxyflavone, 3′,4′,5,7-tetrahydroxyflavone, 4′,5,7-trihydroxyflavanone, 3,3′,4′,5,7-pentahydroxyflavone, 3,3′,4′,5,7-pentahydroxyflavone -3-O-glucoside, and 3,3′,4′,5,7-pentahydroxyflavone-3-O-rutinoside, which are likely responsible for the antifungal activity of the extracts. Overall, this study demonstrates the potential of plant extracts as a sustainable alternative for the management of rice blast.