bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Picture of Health: Seeing the Health of the Chronically Challenged Through Van Gogh's Sunflowers as a Needed Revision of the Clinical Perspective
Authors: Pârvan Alexandra 
Published: January 2025

ABSTRACTThis article identifies and offers a response to several problems that affect the quality of both clinical education and health care services. These matters are: that in clinical training and practice, health, as lived by patients (persons), is not properly considered, and is equated reductively with treating diseases/disorders; that health is seen through disease, and as restricted to a single model defined by an organism's meeting (or being returned to) biochemical or functional standards; that intellectual assumptions instilled in schools of Medicine and Psychology about realities pertaining to healthcare determine an understanding of chronic illness or life with chronic challenges focused on impairment and suffering, and not on the fuller experience of living with illness, disability or neuropsychological challenges that patients have as persons; that arts‐based education reflects the same focus in understanding ‘illness’, and thus neglects giving attention to the creation of personal health states of those living with challenging or debilitating long‐term conditions; that, consequently, the arts are instrumentalized to serve these predefined educational purposes, rather than allowed to inform clinical training through that which is intrinsic or more specific to them. As a way out of these limitations and as an illustration of how things could be done differently, Vincent Van Gogh's paintings of the Sunflowers are used as visual inspiration for how we could change the way we see, and construct new mental representations of ‘health’, ‘chronic illness’ or 'chronic challenges', ‘patient as person’ or even 'person as non‐patient', ‘the clinician's role’ and ‘the identity of clinical practice’. Relying on Van Gogh's depictions of the sunflowers as an example and a visual basis, the article shows how characteristics typical to art (transformation, alternative generation, etc.) can be transferred into the perception and conceptualisation of clinically relevant realities, and discusses the benefits of these changes for clinical practice.
Adult Scissor Bite Case Treatment With Moving Teeth Through Maxillary Sinus
Authors: Lee Sang‐Hoon , Park Jae Hyun , Huh Hee‐Sun , Yu Jae‐Hyung , Chung Dong‐Hwa 
Published: January 2025

ABSTRACTObjectiveThis case report demonstrates the orthodontic treatment to correct a severe scissor bite and occlusal disharmony in a 26‐year‐old female patient, including the use of temporary anchorage devices (TADs) and fixed orthodontic appliances.Clinical ConsiderationsSevere scissor bite is associated with vertical problems, such as molar extrusion. For orthodontic treatment, interradicular TADs were used to intrude the extruded molars, control the inclination of molars, correct dental midline, and improve dental relationships.ConclusionsThis treatment not only achieved successful correction of the scissor bite but also provided adequate occlusion function and improved facial esthetics.Clinical SignificanceTADs provided an effective orthodontic force system to correct the scissor bite. In severe scissor bite cases, a significant amount of maxillary molar intrusion is required, which can increase the risk of moving teeth through the maxillary sinus. Using CBCT images could help in treatment planning for the three‐dimensional movement of teeth during the orthodontic treatment.
Dissolved organic carbon from “white” waters in Amazon basin (Brazil) and the osmoregulatory responses of tambaqui (Colossoma macropomum) in neutral and acidic environments
Authors: Sadauskas‐Henrique Helen , de Souza‐Bastos Luciana R. , Smith D. Scott , Val Adalberto L. , Wood Chris M. 
Published: January 2025

AbstractOptical characterization of dissolved organic carbon (DOC) freshly collected from the circumneutral “white water” of the Rio Solimoes revealed that it had lower aromaticity, lower molecular weight, and a greater autochthonous content than DOC from the acidic “black water” of the Rio Negro. The tambaqui (Colossoma macropomum), a characid member of the Serrasalmidae, is a model neotropical fish that migrates annually between the two rivers. We analysed ionoregulatory responses of the tambaqui over 24 h in ion‐poor water at pH 7.0 and pH 4.0 in the absence and presence of 10 mg L−1 Rio Solimoes DOC (“SOL DOC”). Measured parameters included transepithelial potential (TEP) across the gills, net flux rates, and plasma concentrations of Na+, Cl−, ammonia, and urea, and branchial Na+, K+ −ATPase, H+, ATPase, and carbonic anhydrase activities. Results were compared to our earlier study using similar protocols to examine the ionoregulatory effects of 10 mg L−1 DOC (“SGC DOC”) collected from black water at São Gabriel da Cachoeira (SGC) in the upper Rio Negro. At pH 7.0, SOL DOC had no effect on the negative TEP across the gills. Exposure to pH 4.0 caused a marked depolarization of the TEP to positive values that was not ameliorated by the presence of SOL DOC. This contrasts with SGC DOC that drove TEP more negative at pH 7.0 and fully protected against the depolarization at pH 4.0. However, SOL DOC promoted positive balance of Na+ and Cl− at pH 7.0 and helped ameliorate the negative balance of these ions seen at pH 4.0. This again contrasts with SGC DOC that exacerbated ion losses at pH 4.0. The protective effects of SOL DOC on ion balance maybe related to increased v‐type H+ ATPase activity in the gills, and unrelated to TEP. The very different responses to the two DOCs are discussed with respect to their optical properties, the time that they were in storage prior to testing (SOL <1 month, SGC 2 years), and the life history of the tambaqui in the two rivers.
This unique and precious opportunity: A conversation among feminist administrators about reclaiming the transformative potential of post‐pandemic higher education
Authors: Pratt Menah , Zvonkovic Anisa M. , Oswald Ramona Faith 
Published: January 2025

AbstractIn the fall and winter of 2024, co‐guest editors Ramona Oswald and Anisa Zvonkovic talked with Vice President Menah Pratt about her vision for higher education. Dr. Pratt is internationally recognized for her work in leading change in academic institutions. The discussion centered on the unique and precious opportunity of higher education for students, the transformative potential of this opportunity, at the present moment.
Factors Influencing Daily Living and Ostomy Self‐Care Management in Ostomates: A Mixed Methods Study
Authors: Ertürk Elif Budak , Ari Hacer , Üstündağ Çiğdem , Yilmaz Esra , Topdemir Ülkü 
Published: January 2025

ABSTRACTAimTo examine the factors affecting the ability of ostomates to perform activities of daily living and manage ostomy self‐care.DesignMix method design.MethodThis study was undertaken through survey (descriptive and clinical characteristics form and Katz Activities of Daily Living (ADL)) for collecting the quantitative data (n = 60) and semi‐structured interviews were conducted with patients unable to perform ostomy self‐care for collecting qualitative data (n = 12) between January 2023 and December 2023.ResultsFactors hindering the ability to perform ostomy self‐care were physical reasons (68.3%) and psychological reasons (66.7%). Multiple linear regression analysis revealed that individuals with a chronic disease have a Katz ADL score 12.6 times higher than those without a chronic disease (p = 0.004, OR = 12.665, 95% CI: 2.304–69.614). Qualitative analysis identified three themes as challenges, taking over ostomy care and factors improving the quality of life with ostomy.ConclusionThe findings indicate that having an ostomy impairs individuals' ability to perform daily activities independently and manage their ostomy. Additionally, the presence of a chronic disease in ostomates predicts greater dependence in daily activities. In this regard, support mechanisms should be identified and activated based on the needs of ostomates and chronic diseases, with nursing interventions tailored to address those needs.Implications for the Profession and/or Patient CareA dedicated team of specialised ostomy nurses can offer valuable support by focusing on ostomy management and assessing factors that affect both self‐care and daily activities.ImpactThis study highlights the impact of coping with an ostomy on daily life and self‐care, underscoring the need for targeted support for vulnerable groups and guiding ostomy care nurses in post‐discharge follow‐up and support group organisation.Reporting MethodsSTROBE and GRAMMS checklists.Patient or Public ContributionPatients contributed to the study by sharing their experiences through face‐to‐face interviews during data collection process.
School Attendance Among Autistic Students in Aotearoa/New Zealand: A Population Cross‐Sectional Study Using the Integrated Data Infrastructure
Authors: Bowden Nicholas , Anns Francesca , Vu Hien , Dacombe Joanne , Muir Colette , Russell Jin , van der Meer Larah , Williams John , Clendon Sally 
Published: January 2025

ABSTRACTBackgroundExtant literature indicates autistic students have lower school attendance compared to the general population. However, there remains considerable heterogeneity between studies, a lack of large population‐based studies beyond the UK and US, and insufficient consideration of age and sex differences in attendance rates. The aim of this study was to examine school attendance among autistic compared with non‐autistic students including stratification by age and sex.MethodsThis was a national retrospective cohort study using population‐level data on students aged 5 to 16 years in 2018. Autism was identified using diagnostic information contained within multiple health datasets. Regular attendance was defined as attending 90% or more of school half days. The association between autism and attendance was estimated using complete‐case 2‐level random intercept modified Poisson regression.ResultsAmong 654 438 students, 8427 (1.3%) were autistic. In adjusted analyses, autism was associated with significantly decreased likelihood of regular attendance (incident rate ratio [IRR] 0.88; 95% CI, 0.86–0.90). Age and sex stratification revealed significant age differences with likelihood of regular school attendance lower for younger autistic students (5–11 years) (IRR 0.85; 95% CI, 0.83–0.87) while sex differences were marginal. The most frequent type of non‐attendance among autistic students was justified (including medical) absence (8.2% of recorded attendance hours for autistic students vs. 5.0% for non‐autistic students).ConclusionThis study provides further, whole‐population evidence of the significant disparities experienced by Autistic students. To improve attendance of autistic students, comprehensive and targeted supports are required to help the student, family and school.
Mechanism of Exogenous Melatonin to Alleviate the Fermentation Performance of Saccharomyces cerevisiae Under Copper Stress
Authors: Wei Mengyuan , Zhao Zixian , Que Zhiluo , Li Bohan , Yang Jinyu , Jiang Wenguang , Fang Yulin , Sun Xiangyu 
Published: January 2025

ABSTRACTMelatonin is involved in biological adverse stress response and enhances the ability of yeast to adapt to adverse conditions. This study investigated the mechanism of exogenous melatonin addition to Saccharomyces cerevisiae (S. cerevisiae) under copper stress. The results indicated that the addition of excessive exogenous melatonin (100 mg/L) led to the accumulation of maltose and trehalose in S. cerevisiae, which slowed glucose metabolism and further suppressed the alcoholic fermentation process. The cell morphology, cell wall structure, and the organelle morphology of S. cerevisiae EC1118 under copper stress improved with the addition of 1 μg/mL of melatonin. The results of gas chromatography–mass spectrometry (GC–MS) indicated that melatonin induced more creamy and waxy flavors in the fermentation broth, whereas excessive melatonin led to the production of unpleasant fats with a coconut oil smell. The metabolomics results showed that melatonin promoted the synthesis of Cup1p and increased copper resistance by upregulating the sulfur‐containing amino acids methionine and cysteine. Furthermore, lipid peroxidation and DNA damage were alleviated through the upregulation of AFMK, which protected the integrity of the cell membrane, thereby the physiological mechanism of alleviating copper stress was achieved. Overall, moderate amounts of melatonin reduced the contraction of cells caused by copper stress and promoted the production of flavor substances. This study holds theoretical and practical importance for wine making and industrial wine production under copper stress.
Treatment effect of head extension by cervical collar on moderate obstructive sleep apnea–A randomized controlled trial
Authors: Delijaj Florim , Lindhagen Lars , Johnsson Linus , Kristiansson Per , Lindberg Eva 
Published: January 2025

SummaryAs available treatments in obstructive sleep apnea are all associated with side‐effects or adherence problems, there is a need for alternative treatment options. In this randomized, open, parallel‐group intervention study, the effect of head extension by cervical collar was evaluated in patients with moderate obstructive sleep apnea. One‐hundred patients with moderate obstructive sleep apnea (apneas and hypopneas per estimated hours asleep = respiratory events index: 15–30) were randomized to either lifestyle intervention, or cervical collar in combination with lifestyle intervention. Both groups received lifestyle advice. In addition, the treatment group was treated with a cervical collar, which allows adjustment of head extension, during sleep. Assessment with questionnaires and polygraphy were performed at baseline and after 6 ± 2 weeks. A linear regression model was used to assess a total effect on respiratory events index, which was the primary endpoint. In the intention‐to‐treat analysis, the cervical collar in combination with lifestyle intervention group decreased their respiratory events index (p = 0.008) and oxygen desaturation index (p = 0.008) more than the lifestyle intervention group, with a mean difference of −4.5 and −4.3, respectively. In the sub‐analysis, there was a clear effect on respiratory events index in the supine position (mean difference between the groups −9.1, p = 0.018) but not on non‐supine apnea–hypopnea index (−2.3, p = 0.17). We conclude that head extension by cervical collar during sleep resulted in improved respiratory events index and oxygen desaturation index values in patients with moderate obstructive sleep apnea. Cervical collar can be a second‐line treatment option in this group, especially in positional obstructive sleep apnea.
Long‐Term Outcome of Chronic Hepatitis B—Histological Score and Viral Genotype Are Important Predictors of Hepatocellular Carcinoma
Authors: Eilard Anders , Ringlander Johan , Andersson Maria E. , Nilsson Staffan , Norkrans Gunnar , Lindh Magnus 
Published: January 2025

ABSTRACTCurrent guidelines to prevent hepatocellular carcinoma (HCC) by chronic hepatitis B virus (HBV) infection are based on risk assessments that include age, sex, and virological and biochemical parameters. The study aim was to investigate the impact of predictive markers on long‐term outcomes. The clinical outcomes of 100 patients with chronic hepatitis B were investigated 30 years after a baseline assessment that included liver biopsy. A favourable outcome—HBsAg loss or HBeAg‐negative infection (ENI; previously termed ‘inactive carrier’)—was observed in 74% of all patients, whereas 7% developed HCC. HBsAg loss was observed in 75% of patients with genotype A, compared with 42%, 33% and 0% with genotypes D, B and C, respectively (p < 0.0001). HCC developed in 3 patients (33%) with genotype C as compared with 3 (17%), 1 (2%) and 0 patients with genotypes B, D and A, respectively (p < 0.0001). In multiple logistic regression analysis, both HBsAg loss and HCC were associated with HBV genotype and baseline HBV DNA level, and HCC also with histological score. The results suggest that genotyping and histological assessment may improve outcome prediction and help decisions about HCC screening, particularly in populations with HBV‐infected individuals of mixed geographic origin.
Shell abandonment by a hermit crab is an effective antipredator behavior against a portunid crab
Authors: Harada M. , Yoshino K. , Koga T. 
Published: January 2025

AbstractWhen hermit crabs recognize the risk of predation, they generally hide inside their shells or flee from the area, and little is known about their escape behaviors after being captured by a predator. We discovered that the hermit crab Pagurus filholi abandons its shell and attempts to flee when captured by the predatory crab Charybdis japonica, and we examined the effectiveness of this behavior in laboratory experiments. We fed captive C. japonica with P. filholi occupying gastropod shells. When the C. japonica could not break the shell even a little, it gave up and the P. filholi neither abandoned its shell nor was eaten. However, when the predator succeeded in partially breaking the shell, the hermit crab often abandoned the shell, and when it did so, it often survived. Once the predator had completely broken the shell open (implying that the shell has been broken to the extent that it no longer has any structural integrity), all hermit crabs that remained back in the shell (22/22) were consumed, and those that abandoned the shell were also often consumed (3/5). Therefore, hermit crabs do not need to abandon their shells if a predator is unable to break the shell even slightly, but if a predator begins to break the shell, they have a better chance of survival if they abandon their shells at an early stage.
A randomised feasibility trial comparing group and individual format GROUPS FOR HEALTH interventions for loneliness in people who experience psychosis
Authors: Hogg Lorna I. , Smith Laura G. E. , Haslam Catherine , Coxhill Lyndsay , Kurz Tim , Hobden Georgina , Morrison Anthony P. 
Published: January 2025

AbstractObjectivesLoneliness in people who experience psychosis is common and associated with poor mental health. In this randomised trial, we tested the feasibility and acceptability of an adapted Groups for Health (G4H) intervention for loneliness, delivered in group or individual format.DesignMixed methods, two‐arm feasibility randomised controlled trial.MethodsForty individuals who self‐identified as having psychosis were recruited from UK mental health care services, recovery colleges and charities. G4H was modified for people with psychosis, with participants randomised to receive the intervention delivered via group (N = 20) or individual (N = 20) format. The primary outcomes related to trial acceptability and feasibility. Exploratory repeated measures ANOVAs and t‐tests evaluated differences between formats over time in loneliness, wellbeing and possible mechanisms of change including social identification, identity integration and perceived in‐group and out‐group empathy. Measures were completed at baseline, end of treatment and 1‐ and 6‐month follow‐up.ResultsRecruitment, retention and trial acceptability ratings for both group and individual formats of G4H were acceptable to good. No participants reported experiencing a serious adverse event. Exploratory ANOVAs indicated no differences related to format but positive change in key variables of loneliness, wellbeing, social identification and identity integration over time. T‐tests for loneliness indicated that this change was step‐wise from baseline, through end of treatment to 1‐month follow‐up.ConclusionsG4H is a feasible intervention for people with psychosis who identify as lonely and it can be delivered in either group or individual formats. This feasibility trial provides support for a future full randomised controlled trial.
Orthodontic Treatment of Patients With Disabilities in Norway: A Survey Among Orthodontists
Authors: Arntsen Torill , Axelsson Stefan , Sun Yi‐Qian , Nordgarden Hilde , Vandevska‐Radunovic Vaska 
Published: January 2025

ABSTRACTAimThe objective of this study was to examine orthodontic treatment of patients with disabilities in Norway, as perceived by orthodontists.Methods and ResultsA digital questionnaire was sent out to the 220 registered members of the Norwegian Orthodontic Society and a response rate of 41% (n = 90) was achieved. The majority (92%) had received referrals for patients with disabilities, 53% reported treating up to 10 patients, while 37% reported treating up to 50 patients in the last 5 years. Most of the participants (64%) showed a willingness to treat more patients with disabilities, with this interest significantly and conversely linked to years in practice (p = 0.02, chi‐squared test). Orthodontists desire more referrals to increase patient intake, and also financial incentives play a relevant role in this context. Regarding the preferred location for orthodontic treatment for patients with disabilities, 34% prefer treatment in specialized centers rather than the current setup in optional private practices. An association exists between this perspective and the readiness to treat additional patients (p = 0.009)ConclusionMost orthodontists in Norway have treated patients with disabilities. Among the surveyed orthodontists, a notable 64% expressed a positive inclination toward treating more patients with disabilities or initiate such services. To enhance their acceptance of these patients, it seems crucial to increase referrals and provide improved financial incentives.
Dropping gems: How a critical community of practice supported science teacher leaders to develop resources for anti‐racist science teaching
Authors: Porter Sara C. , Worsley Ti'Era D. 
Published: January 2025

AbstractAddressing systemic racism in science, technology, engineering, and mathematics (STEM) education is essential to improving science education for students of Color. In this article, we argue that science teacher leaders (STLs) are one mechanism to address this need. However, they likely need access to resources and information to address the multiple needs of science teachers when tasked with addressing issues of racism in STEM. We operationalized STLs who seek out these resources as critical boundary spanners and designed a professional learning program to support their work. We used design‐based research methods to test the conjecture that a critical community of practice will support STLs as critical boundary spanners. We found that three key features of the professional learning program supported the STLs as critical boundary spanners: collectively defining anti‐racist science teaching, modeled facilitation of anti‐racist science activities, and sharing their learning with other STLs and science teachers. These findings contribute valuable insights into the support structures needed for STLs engaged in the vital work of advancing racial justice in science education.