bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimalisasi Peran Petugas Kesehatan: Dokumentasi Riwayat Kesehatan Siswa Cegah Narkoba dan IMS
Authors: Prihatiningsih Diah , Bintari Ni Wayan Desi , Devhy Ni Luh Putu , Purwanti Ika Setya , Widana Anak Agung Gde Oka 
Published: January 2024

Masalah kesehatan remaja, termasuk penyalahgunaan narkoba dan infeksi menular seksual (IMS), menjadi sorotan global, juga bagi Indonesia. Pandemi COVID-19 memperparahnya dengan pembatasan kegiatan sekolah. Data menunjukkan bahwa pada 2018, 26,6% dari penduduk Indonesia adalah remaja. Penyalahgunaan narkoba pada remaja memiliki dampak serius pada kesehatan fisik dan mental. Peran petugas kesehatan merupakan kunci dalam edukasi, pencegahan, dan dokumentasi riwayat kesehatan siswa. Melalui kader kesehatan UKS sebagai role model, sekolah dapat mempromosikan kesehatan dan menyampaikan informasi tentang bahaya penyalahgunaan narkoba dan IMS. Peran Usaha Kesehatan Sekolah (UKS) menjadi strategis dalam mencapai tujuan mewujudkan siswa bebas NAPZA dan IMS. Pengabdian masyarakat bertujuan meningkatkan pengetahuan kader kesehatan UKS SMK Kesehatan PGRI Denpasar tentang bahaya penyalahgunaan NAPZA dan IMS. Kegiatan dilakukan melalui ceramah, diskusi, dan demonstrasi pemeriksaan NAPZA serta pencegahan IMS oleh tim penyuluh pada tanggal 29-31 Mei 2023. Hasilnya menunjukkan peningkatan pengetahuan kader kesehatan UKS dan siswa terhadap NAPZA dan IMS. Analisis statistik menunjukkan perbedaan yang signifikan (p <0,001). Siswa kader kesehatan dapat mempraktekkan tahapan pemeriksaan NAPZA dengan metode strip test. Dengan memberikan materi ini, diharapkan dapat mendukung peran UKS dalam mencapai tujuan mewujudkan siswa-siswi bebas NAPZA dan IMS.

The issue of adolescent health, including drug abuse and sexually transmitted infections (STIs), has garnered global attention, including in Indonesia. The COVID-19 pandemic has exacerbated this concern with school activity restrictions. Data indicates that in 2018, 26.6% of Indonesia's population comprised adolescents. Drug abuse among adolescents has serious implications for physical and mental health. The role of healthcare professionals is crucial in educating, preventing, and documenting students' health history. Through the UKS health cadres serving as role models, schools can promote health and convey information about the dangers of drug abuse and STIs. The role of School Health Effort (UKS) is strategic in achieving the goal of creating drug-free and STI-free students. Community service aims to enhance the knowledge of UKS health cadres at SMK Kesehatan PGRI Denpasar regarding the dangers of drug abuse and STIs. Activities involve lectures, discussions, and demonstrations of drug testing and STI prevention by the counseling team from May 29 to 31, 2023. The results show an increase in knowledge among UKS health cadres and students regarding drugs and STIs. Statistical analysis reveals a significant difference (p <0.001). Health cadet students can practice drug testing stages using the strip test method. By providing this material, it is hoped to support the role of UKS in achieving the goal of creating drug-free and STI-free students.
Estrategias de comercialización para emprendimientos asociativos artesanales en la provincia de Cañar – Ecuador
Authors: Jerez Morocho Erika Nataly , Ordoñez Gavilanes Magdalena Emilia 
Published: January 2024

Gestionar los procesos de comercialización en emprendimientos asociativos artesanales es una tarea ardua y crucial, pues representa un factor clave para su posicionamiento. Desde esta perspectiva el estudio contempla el objetivo de diseñar un modelo estratégico para la gestión de los procesos de comercialización de barras de cereales en el mercado de la provincia de Cañar-Ecuador; para ello se utilizó una metodología de enfoque mixto, con un alcance descriptivo y un diseño de campo de corte transversal; considerando tres estratos de población: socios de la asociación, propietarios de locales comerciales y mercado meta, con una muestra de 430 agentes informantes, se analizaron aspectos relacionados con la gestión de los procesos de comercialización desde el marketing estratégico y operativo. Los resultados muestran que un negocio artesanal exitoso necesita marketing estratégico, que incluya comprensión del mercado, identificación de nichos, satisfacción de las necesidades del consumidor, construcción de marca y selección de distribución adecuada. Desarrollar un modelo estratégico para la gestión comercial puede impulsar el posicionamiento, el crecimiento, la rentabilidad y construir relaciones significativas a largo plazo con los clientes, enfocándose en estrategias de precios, comunicación en redes sociales, amplia distribución, servicio al cliente personalizado y una estrategia orientada a las necesidades del cliente, operación cíclica que impulsa la innovación y aumenta las ventas.
Feminicidios en la literatura latinoamericana, una lectura sociológica
Authors: Acosta Reveles Irma Lorena , Becerra Cuevas Norma Angélica 
Published: January 2024

Acercarse desde la narrativa al núcleo de la violencia feminicida es posible. Puede constituir, incluso, una vía de enriquecimiento a métodos ortodoxos de análisis social porque el discurso literario se alimenta —crudamente, en este caso— de la realidad. Teniendo como premisa que el arte literario retrata con criterios estéticos quiénes somos y cómo nos movemos en tanto sociedad (Goldmann, 1964, Lukács,1989; Chuaqui Numán, 2002; Ortiz et. al. 2021), el objetivo de este artículo es demostrar a través un conjunto de teorizaciones sociológicas, que las representaciones literarias constituyen un valioso acervo para descifrar las causas de la violencia de género. Por tanto, a través del análisis de contenido literario es posible sacar a la luz los pormenores de las instituciones sexistas, de las que somos todos partícipes. En el plano metodológico, los insumos para la valoración hermenéutica fueron obras literarias referidas a feminicidios en su trama, cuentos y novelas publicadas en las tres últimas décadas en países de América latina, y referidas a sucesos del mismo contexto geográfico. El criterio numérico para agotar el examen fue la saturación, procediendo la lectura conforme se fueron encontrando las evidencias. Se revisaron finalmente diez piezas literarias entre una gran cantidad de títulos que refieren asesinatos de mujeres por el sólo hecho de serlo. Se concluye que (1) los relatos de feminicidios, sean en el espacio público o íntimo, emulan la interacción típica entre personas que, por ser de distinto sexo, no están investidas socialmente del mismo valor y dignidad; y (2) los fragmentos literarios comunican con eficacia un statu quo en el cual los hombres ejercen poder sobre las mujeres, en virtud de un entramado de prácticas, normativas, roles, creencias y significados que reproducen privilegios masculinos a expensas de la potencia vital de las mujeres.
BRANDING POSITIONING & VALUE DELIVERY & MARKETING COMMUNICATION ON SUCCESSFUL BUSINESS LONG TERM GROWTH
Authors: Rubedo Hendar , Narimawati Umi , Syafei M Yani 
Published: January 2024

Objectives of the research are to understand the influence of Branding Positioning, Value Delivery and Marketing Communication on Successful Business Long Term Growth. Quantitative approach using survey method is used in studying 30 SME business organizations in Bandung. Structural equation modelling based on covariance is used to analyse data. Results of the study are as follows: 1) Branding Positioning, Value Delivery and Marketing Communication affect significantly on Successful Business Long Term Growth simultaneously; 2) Branding Positioning affects significantly on Successful Business Long Term Growth partially; 3) Value Delivery affects significantly on Successful Business Long Term Growth partially; 4) Marketing Communication affects significantly on Successful Business Long Term Growth partially. Thus, business long term growth is important for the business organizations in order to gain competitive advantage and profit.
The Roles of Awareness, Interest, Evaluation, Trial on Adoption and its Impact on Purchase Decision: Study on New Product of ”Wuling” Electric Car Consumers in Bandung
Authors: Cahyati Tetet , Munandar Dadang 
Published: January 2024

The objectives of this study is to know the influence of the new product adoption on purchase decision among the consumers of the Wuling Electrical Vehicle in Bandung. The research employs a quantitative approach and survey. By using the purposive method, 96 consumers in Bandung were selected as the respondents of the study. The writer uses path analysis to analyze the data. Findings of the research are as follows: 1) Awareness, Interest, Evaluation and Trial affect significantly Adoption simultaneously; 2) Awareness affects significantly Adoption partially; 3) Interest affects significantly Adoption partially; 4) Evaluation affects significantly Adoption partially; 5) Trial affects significantly Adoption partially; and 6) Adoption affects Purchase Decision significantly. Thus, the adoption process of the new electric car positively affect the consumers purchase decisions whether or not they will buy the electrical vehicle.
Kejadian Stunting pada Balita Berhubungan dengan Pemberian ASI eksklusif Selama 1000 Hari Pertama Kelahiran
Authors: Harismayanti Harismayanti , Mansur Rona Febriyona 
Published: January 2024

Fenomena cakupan ASI eksklusif yang masih rendah secara jangka panjang akan berimplikasi terhadap tumbuh dan kembang anak. Penelitian ini mengeksplorasi hubungan antara pemberian ASI eksklusif dan kejadian stunting pada balita di Wilayah Kerja Puskesmas Limboto, Kabupaten Gorontalo. Dengan melibatkan 93 responden ibu Balita berusia 7–24 bulan, penelitian ini menggunakan pendekatan cross-sectional, kuantitatif untuk variabel riwayat pemberian ASI eksklusif dan kualitatif dengan wawancara mendalam faktor pemberian ASI eksklusif, analisis data menggunakan metode uji Chi-square. Sebagian besar balita pada kategori sangat pendek (16,1%), dan pendek (14,0%), kemudian yang tidak menerima ASI eksklusif cenderung mengalami stunting (p=0,001). Faktor pemberian ASI eksklusif antara lain fasilitas kesehatan yang jaraknya cukup jauh sehingga pelayanan kesehatan dan penyuluhan yang didapatkan tidak maksimal, kurangnya pemahaman ibu akan pentingnya status gizi selama 1000 hari pertama kehidupan atau selama masa kehamilan hingga anak berusia 2 tahun, ibu dengan riwayat kondisi KEK, riwayat anemia dan tidak teratur mengkonsumsi tablet Fe saat hamil kebanyakan melahirkan anak dengan stunting. Upaya untuk mengatasi masalah stunting diperlukan kerjasama lintas sektoral yang baik. Penelitian lanjutan diperlukan dengan memperhatikan kepada faktor budaya dan kontekstual.
Pediatric Ewing Sarcoma of Kidney: A Case Series and Review of Literature
Authors: Salim Areej , Ali Sajid , Latif Tariq 
Published: January 2024

Introduction: Renal Ewing sarcoma is an aggressive and rare malignancy affecting children and adolescents. Limited data on its management contributes to uncertainties in treatment Case description: We present two pediatric cases of Renal Ewing Sarcoma. Both cases emphasize the significance of accurate diagnosis, multimodal treatment, and long-term follow-up in achieving favourable outcomes. Accurate diagnosis of renal Ewing sarcoma is crucial for effective management. Multimodal treatment involving neoadjuvant chemotherapy, surgical resection and staging with lymph node sampling, and chemotherapy continuation has shown promising results in our cases. Long-term follow-up is essential for monitoring disease progression and ensuring optimal outcomes. Practical Implications: There is limited data published about these renal tumors, especially in the pediatric population, and most studies lack long-term follow-up (6,7,20), with uncertain management due to limited data. This data will add to the newer and multimodal approach and form the basis for future meta-analysis to help formulate guidelines in upcoming international meetings. Continued research efforts are necessary to optimize strategies and improve the prognosis for pediatric patients with renal Ewing sarcoma.
The Effects of Alpha Lipoic Acid on Oxidative Stress, Lipid Profile, and Blood Glucose Levels in Type 2 Diabetic Male Sprague Dawley Rats
Authors: Khan Barkat Ullah , Arshad Sidra , Ikram Faiza , Yousef Iftekhar , Naizi Inam , Ismaeel Muhammad 
Published: January 2024

Objective: To determine the effect of Alpha Lipoic Acid (ALA) on blood glucose, lipid profile, and oxidative stress in streptozotocin-induced type II diabetic male Sprague Dawley rats.Study Design: Laboratory-based experimental study.Place and Duration of the Study: The study was carried out at the Physiology Research Lab, Army Medical College, Rawalpindi, Pakistan, from 20th January 2021 to 24th June 2021.Methods: Thirty Sprague Dawley (SD) rats were divided into three equal groups. Group I was given a normal standard rat diet. In Groups II and III after feeding a diet rich in fat and calories for 2 weeks, after feeding a diet rich in fat and calories for 2 weeks, a single low dose of streptozotocin was injected for Type 2 Diabetes Mellitus (T2DM) induction. Alpha Lipoic Acid 30 mg/kg body weight/day was administered intraperitoneally in Group III for 01 weeks after the development of T2DM.Results: The blood glucose, lipid profile, and serum Malondialdehyde levels were deranged in the diabetic group. After Alpha Lipoic Acid supplementation, the blood glucose levels, Serum MDA, and levels of triglycerides, cholesterol, and Low Density Lipoproteins decreased, whereas High Density Lipoproteins level were significantly raised (p <0.001) in group III as compared to the diabetic group II. Conclusion: Treatment with Alpha Lipoic Acid reduces oxidative stress and improve reduces oxidative stress and improves glycemic and lipid profiles in T2DM rats.
How to cite this: khan BU, Arshad S, Ikram F, Yousef I, Naizi I, Ismaeel M. The Effects of Alpha Lipoic Acid on Oxidative Stress, Lipid Profile and Blood Glucose Levels in Type 2 Diabetic Male Sprague Dawley Rats. Life and Science. 2024; 5(1): 89-94. doi: http://doi.org/10.37185/LnS.1.1.405
Retinal Nerve Fiber Layer Thickness (RNFLT) in Myopic & Hypermetropic Eyes in a Subset of Pakistani Population
Authors: Mukhtar Sahrish , Hassan Nuzhat , Lakhani Mubina , Fatima Urooj , Shaheen Sadaf , Raza Iffat 
Published: January 2024

Objective: This study aimed to evaluate retinal nerve fiber layer (RNFL) thickness in healthy individuals with myopic and hypermetropic eyes, using optical coherence tomography (OCT).Study Design: A cross-sectional study. Place and Duration of Study: The study was carried out at the Department of Ophthalmology, Dr. Akil bin Abdul Qadir Institute of Ophthalmology, Karachi, Pakistan from January 2015 to June 2015.Methods: In this study, 300 eyes were included were examined using standard protocols by a single examiner. Subjects with a history of diabetic or hypertensive retinopathy, raised intraocular pressure (> 21mmHg), and previous intraocular or laser surgery were excluded from the study. The mean retinal nerve fiber layer thickness was calculated in both myopic and hypermetropic eyes. Results: The mean global retinal nerve fiber layer thickness (RNFLT) in myopic eyes was found to be 93.98 ± 8.57 μm. In hypermetropic eyes, it was found to be 101.00 ± 6.58. This variation was found to be statistically significant with p-value of 0.001.Conclusion: We concluded that individuals with myopic eyes had significantly reduced retinal nerve fiber layer thickness whereas those with hypermetropic eyes showed an insignificant increase in RNFLT compared to emmetropic eyes.How to cite this: Mukhtar S, Hassan N, Lakhani M, Fatima U, Shaheen S, Raza I. Retinal Nerve Fiber Layer Thickness (RNFLT) in Myopic & Hypermetropic Eyes in a Subset of Pakistani Population. Life and Science. 2024; 5(1): 54-60. doi: http://doi.org/10.37185/LnS.1.1.480
Awareness and Acceptability of Breast Reconstruction Among Women with Breast Cancer in Twin Cities of Islamabad and Rawalpindi
Authors: Mehmood Mehwish , Aslam Ayesha , Ahmed Waqas , Aman Sameena , Ali Ahmed , Feroze Hira , Saleem Nousheen 
Published: January 2024

Objective: To determine the frequency of awareness and acceptability of breast reconstruction surgery among women in the twin cities of Islamabad and Rawalpindi.Study Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Department of Plastic Surgery, Fauji Foundation Hospital, Rawalpindi, Pakistan, from October 2022 to June 2023.Methods: A total of 271 patients between 20-70 years of age with a diagnosis of breast cancer were included. Demographic details, including marital status, education, residence, occupation, family history, awareness of breast reconstruction, and source of information about breast reconstruction, were documented on a proforma. All patients received information regarding breast reconstruction, and records of the frequency of acceptability and contributing factors were made. Data analysis was carried out by using SPSS 25.0.Results: The mean age of patients was 43.41 ± 8.98 years. Out of 271 patients, 114 patients (42.1%) had an awareness of breast reconstruction. The primary source of information was the treating physician in 60 out of 114 patients (52.6%). Breast reconstruction acceptability was reported in 110 out of 271 patients (40.6%). Family support was the most common reason for acceptance in 43 out of 110 patients (39.1%).Conclusion: Efforts need to be made at the community level to educate the general population about breast cancer treatment options, including breast reconstruction. Education was significantly associated with increased awareness and acceptability for breast reconstruction. Better cosmetic outcomes and family support were the factors for increased acceptability, while financial constraints and family pressures were reasons for the vice versa.How to cite this: Mehmood M, Aslam A, Ahmed W, Aman S, Ali A, Feroze H, Saleem N. Awareness and Acceptability of Breast Reconstruction Among Women with Breast Cancer in Twin Cities of Islamabad and Rawalpindi. Life and Science. 2024; 5(1): 9-15. doi: http://doi.org/10.37185/LnS.1.1.509
Effectiveness of Postoperative Analgesia with Rectal Placement of Diclofenac Sodium in Patients Undergoing Gynecological and Obstetrical Surgeries under General Anesthesia
Authors: Saeed Riffat , Mahboob Anam , Mahmood Ali Syed , Latif Amer , Ammar Tooba , Kakepotto Irfan Ali 
Published: January 2024

Objective: To determine the frequency of need for postoperative intravenous analgesia after rectal diclofenac suppository in patients undergoing lower abdominal gynecological or obstetrical surgery under general anesthesiaStudy Design: Cross-sectional study.Place and Duration of Study: The study was carried out at the Operation Theater and Postoperative Ward of Sheikh Zayed Hospital, Lahore, Pakistan from January 2021 to July 2021.Methods: A total of 245 women undergoing gynecological and obstetrical surgeries under general anesthesia were enrolled in the study using non-probability consecutive sampling. All the participants were recruited after obtaining informed consent and meeting the inclusion criteria. All subjects had a single 100mg diclofenac suppository inserted rectally after undergoing general anesthesia, and their Visual Analog Scale (VAS) scores for postoperative analgesia were recorded immediately after surgery and again at 1, 6, and 24 hours.Results: The mean age of the patients was 37 years, with a standard deviation of 6.2. The mean VAS (Visual Analog Scale) scores at 1, 6, 12, and 24 hours were 3 (±1.24), 5 (±1.46), 7 (±1.93), and 6 (±2.14), respectively. The need for rescue analgesia was reported in 15.9% of cases at 1 hour, 37.1% at 6 hours, 82% at 12 hours, and 68.2% at 24 hours.Conclusion: The administration of diclofenac via rectal placement led to a notable decrease in Visual Analog Scale scores and a lower incidence of needing additional pain relief within the first 6 hours after surgery.
How to cite this: Saeed R, Mahboob A, Ali SM, Latif A, Ammar T, Kakepotto IA. Requirement of Postoperative Analgesia after Per Rectal Placement of Diclofenac Sodium in Patients Undergoing Gynecological and Obstetrical Surgeries under General Anesthesia. Life and Science. 2024; 5(1): 120-125. doi: http://doi.org/10.37185/LnS.1.1.515
Maternal Hypothyroidism-Induced Impaired Development of Neurons in Rat Offspring: Insights for Antenatal Care
Authors: Fahad Tayyaba , Ali Shabana , Qureshi Tayyaba , Khan Noor Fatima 
Published: January 2024

Objective: To determine the effect of maternal hypothyroidism on the development of neurons in the motor cortex of rat pups by using light microscopy. Study Design: Laboratory-based experimental study.Place and Duration of Study: The study was carried out in collaboration with the National Institute of Health (NIH) Islamabad and the Department of Anatomy, Islamic International Medical College, Riphah International University, Islamabad, Pakistan from March 2023 to May 2023.Methods: In this study, 24 females and 12 male Sprague dawley rats were sorted into control and hypothyroid groups. The control group received a standard diet and plain drinking water throughout the study. In contrast, the hypothyroid group had 4.5mg of propylthiouracil administered per rat per day, mixed into their drinking water. This treatment started a week before mating and continued until three weeks after delivery. Once successful mating was confirmed via vaginal plugs, gestation proceeded, and newborn pups were born after nd three weeks, having full access to maternal lactation for 21 days. On the 22 day after birth, dissection took place, and the brains of the pups were carefully removed. Coronal sections of the motor cortex were then obtained for subsequent examination.Results: The control group displayed a typical pattern of neurogenesis, characterized by the normal structure of cortical neurons. On the other hand, intracellular vacuolation, glial cell necrosis, and reduced Nissl rim thickness were statistically significant in hypothyroid group which collectively pointed to atypical neurogenesis. Conclusion: This study highlights the adverse effects of maternal hypothyroidism on the structural integrity of cortical neurons. It focuses on increasing awareness and implementing thorough prenatal healthcare strategies.How to cite this: Fahad T, Ali S, Qureshi T, Khan NF. Maternal Hypothyroidism-Induced Impaired Development of Neurons in Rat Offspring: Insights for Antenatal Care. Life and Science. 2024; 5(1): 68-74. doi: http://doi.org/10.37185/LnS.1.1.525
MORPHOLOGICAL INDICATORS OF THE BLOOD SYSTEM IN CHILDREN 6-10 YEARS OF THE CHECHEN REPUBLIC
Authors: Морякина Светлана Васильевна , Джаватханова Мадина Турпал-Алиевна , Алимханова Танзила Исламовна 
Published: January 2024

Научная статья посвящена исследованию возрастных особенностей системы крови у детей разного пола Чеченской Республики. В результате было установлено, что мальчики в возрасте 8 лет имели более высокое количество эритроцитов, которое превышало значение шестилетних более чем на 10,8%. У мальчиков 10 лет уровень гематокрита был ниже на 5,8% в сопоставлении с мальчиками 7 и 8 лет. Среди девочек 8 лет в сопоставлении с 10-ти летними, гематокритное число было снижено на 2,5%.
A scientific article is devoted to the study of the age characteristics of the blood system in children of different genders of the Chechen Republic. As a result, boys aged 8 were found to have higher red blood cell counts, which exceeded the six-year-olds by more than 10.8%. Boys 10 years old had a 5.8% lower hematocrit rate compared to boys 7 and 8 years old. Among girls aged 8 years compared to 10 years, the hematocrit number was reduced by 2.5%.
COMPREHENSIVE ASSESSMENT OF THE CITY'S WATER SUPPLY PROBLEMS
Authors: Болдырева Алина Юрьевна , Помогаева Валентина Васильевна 
Published: January 2024

В статье приведена оценка проблем водоснабжения города с числом жителей до 60 тыс. человек. Показаны направления решения выявленных проблем.
The article provides an assessment of the problems of water supply in a city with a population of up to 60 thousand people. The directions of solving the identified problems are shown.