bluuebunny/crossref_metadata_2025_split huggingface dataset:
Manajemen Strategi Usaha Perikanan Budaya Ikan Hias Berbasis Komoditas Unggulan Di Kabupaten Tulungagung
Authors: Rahayu Andra Rejekining 
Published: January 2025

Kabupaten Tulungagung memiliki potensi perikanan budidaya air tawar baik buddaya ikan konsumsi maupun budidaya ikan hias. Pada akhir-akhir ini terjadi kelesuhan usaha budidaya ikan air tawar konsumsi dikarenakan harga pakan ikan yang notabene bahan bakunya masih banyak impor sehingga benefit yang dihasikan tidak seperti beberapa tahun yang lalu. Usaha budidaya ikan hias dipandang merupakan salah satu solusi untuk meningkatkan pendapatan para pembudidaya ikan dikarenakan kebutuhan pakan ikan hias relative sedikit dibandingan dengan ikan konsumsi yag membutuhkan modal sebesar 70 % untuk kebutuhan pakan. Untuk mengembangkan usaha budidaya ikan hias perlu diketahui posisi apakah sector perikanan ikan hias di Kabupaten Tulungagung merupakan sector basis atau non basis. Hal ini bertujuan untuk memberikan arah kebijakan pembangunan daerah sehingga pendapatan para pembudidaya ikan di Kabupaten Tulungagung dapat meningkat. Jenis penelitian ini adalah penelitian kualitatif. Dari penelitian ini diperoleh hasil bahwa sector perikanan budidaya ikan hias masuk dalam sector potensial atau berkembang sangat cepat. Diperoleh komoditas unggulan berupa ikan gupi, mas koki, lemon, manfish, marble, moli dan red fin. Manajemen Strategi untuk mengembangkan usaha budidaya ikan hias komoditas unggulan ini dapat dilakukan dengan growth oriental strategy
Comparative Study between Common and Individual MPPT Controller Using Fuzzy Logic Control for Hybrid System (Photovoltaic/Wind Energy Conversion System)
Authors: Bouguerra Zahira 
Published: January 2025

This paper aims to hybridize photovoltaic systems (PVs) with wind energy conversion systems (WECs) by using different architectures, with a comparative study to distinguish the best hybridization method that gives the best performance. The first architecture uses an individual maximum power point tracking (MPPT) controller for each system independently. The photovoltaic generator is connected to the DC/DC converter and is controlled by fuzzy logic control (FLC) to track maximum power. In the WECs system, which is based on a permanent magnet synchronous generator (PMSG), the DC/DC converter is also controlled by FLC to maximize its output power. The second architecture uses a single MPPT controller for both systems; the PV generator and AC/DC converter of the WECs are connected to a common DC/DC converter controlled by the FLC. The hybrid system is connected to the grid via an inverter, which is controlled by voltage-oriented control (VOC) to separate the control of the active and reactive powers. The system studied was specially designed to be installed in the building, consisting of a photovoltaic system providing 25 kW and a WECs composed of three small turbines, each providing 8.5 kW. The MATLAB simulation results are presented under varying conditions of sunlight, wind speed, and load requirement, proving that; the using of an individual MPPT controller gives better performances than the single MPPT controller. However, the last topology provides more power than the first topology (over 1 kW) because of the reduced number of converters used.
Efficacy and Cost Economics of Bio-Pesticides and Botanical Extracts Against Cabbage Butterly Pieris Brassicae Nepalensis Doubleday in Cauliflower Crop in Ilam, Nepal
Authors: Subedi Anupa , Tiwari Sundar , Mishra Niraj 
Published: January 2025

A field experiment was conducted to compare the efficacy and profitability of using bio-pesticides and locally available botanical extracts for the management of cabbage butterfly Pieris Brassicae Nepalensis Doubleday for cauliflower production. The management study was established in a farmer’s field in Barhabasti, Ilam, Nepal. Eight different types of management treatments were deployed in a randomized complete block design (RCBD) with three replications. The treatments were i) Bacillus thuringensis var kurstaki (2 gm /lt) ii) Metarhizium Anisopliae (2.5 ml /lit) iii) Beauveria Bassiana (3 ml /lit) iv) Acorus calamus (1:5) v) Lantana camara (1:5) vi) Neem oil (1.5 ml /lt) vii) Cow urine (1:4) viii) Control. Results showed that bio-pesticides and botanical extracts were significantly superior over control. L. camara treated plots contained the lowest larval population compared to all other treatments. The order of effectiveness of the treatments based on the population reduction was L. camara > A. indica > A. calamus > Cow urine > M. Anisopliae > B. thuringiensis > B. Bassiana > control. The above treatments were also safe for natural enemies since there was a non-significant mortality effect of bio-pesticides on natural enemies. The highest benefit-cost ratio (2.36) was recorded in neem oil-treated plots that were superior to all other treatments. To summarize, this study can help to develop an IPM protocol for the sustainable management of cabbage butterflies in crucifer fields.
SAARC J. Agric., 22(2): 127-138 (2024)
Selection of the Best Time Series Arima Model to Forecast Onion Production in Bangladesh
Authors: Hasan Mohammad Rashidul 
Published: January 2025

Onion is one of the most commonly used spices in Bangladesh for preparing food and illness treatment. Since the demand for onions is rising daily, accurate projections must be made to implement policies based on that need. Hence, the study attempts to select the best Auto-Regressive Integrated Moving Average (ARIMA) model to forecast onion production in Bangladesh. Initially, the study considers Bangladesh's yearly onion production (in hg/ha) data set from 1971 to 2017. The study then applied the Box-Jenkins approach to build the model and forecast the onion production in Bangladesh. The study also used data from 2018 to 2022 to compare the forecasted values. The AIC, AICC, and BIC values, error metrics, and residuals of the fitted model were assessed using onion production data. The comparative analysis shows that ARIMA (0, 2, 1) is the best model for precise forecasts of onion production in Bangladesh. The proposed model may help policymakers forecast accurately and know the future trend of onion production in Bangladesh.
SAARC J. Agric., 22(2): 169-180 (2024)
Correlation between CT-derived fractional flow reserve and myocardial strain in ischemic heart disease patients with single coronary artery stenosis assessed based on CCTA
Authors: Ren Ruichen , Li Wenting , Zhao Qingyuan , Qi Chengcheng , Zhang Xiaoxue , Peng Mingyu , Su Duwang , Han Pei , Zhang Yang 
Published: January 2025

PurposeWe aimed to investigate the correlation between CT-derived fractional flow reserve (CTFFR) and myocardial strain in patients with single coronary artery stenosis and to investigate the diagnostic value of CTFFR in identifying impaired myocardial strain.MethodsWe selected 89 patients, categorized into three groups based on the affected coronary artery: 36 with left anterior descending (LAD), 23 with left circumflex (LCX), and 30 with right coronary artery (RCA) stenosis, along with 25 healthy controls. We investigated correlations between CTFFR and both global and regional myocardial strain parameters. Additionally, we assessed the ability of the CTFFR to detect impaired myocardial strain in these patients.ResultsIn this study, no significant difference was found in overall myocardial strain between the patient and control groups. However, regional longitudinal strain (LS) and circumferential strain (CS) in the myocardial areas supplied by stenotic coronary arteries was significantly lower in each patient group compared to the others (P &lt; 0.001). The CTFFR exhibited a strong negative correlation with both regional and global myocardial strain, with a stronger association for regional strain. Particularly in group LAD, CTFFR in optimal diastole phase (CTFFR-D) was negatively correlated with Endo-LS (r = −0.66, P &lt; 0.001). Receiver operator characteristic curve (ROC) analysis indicated that CTFFR were effective in diagnosing impaired myocardial strain, particularly LS.ConclusionThere is a strong correlation between CTFFR, which is a functional measure for assessing coronary artery stenosis, and myocardial strain. CTFFR can identify impaired myocardial strain and can be used as an indirect indicator of myocardial ischemia.
Long-term safety of dexamethasone sodium phosphate encapsulated in autologous erythrocytes in pediatric patients with ataxia telangiectasia
Authors: Koenig Mary Kay , Leuzzi Vincenzo , Gouider Riadh , Yiu Eppie M. , Pietrucha Barbara , Stray-Pedersen Asbjørg , Perlman Susan L. , Wu Steve , Burgers Trudy , Borgohain Rupam , Kandadai Rukmini Mridula , Meyts Isabelle , Bucciol Giorgia , Udwadia-Hegde Anaita , Yadav Ravi , Roberts Donna , Dane Aaron , Roden Maureen , Thye Dirk , Horn Biljana , Lederman Howard M. , Whitehouse William P. 
Published: January 2025

BackgroundDexamethasone sodium phosphate (DSP) encapsulated in autologous erythrocytes (EryDex) was developed as an alternative to standard glucocorticoids in an effort to eliminate chronic steroid toxicity while preserving efficacy. The primary objective of this report is to describe the safety of long-term use of EryDex in treatment of pediatric patients with ataxia telangiectasia.MethodsThis is a post-hoc analysis of patients treated with EryDex for a minimum of 24 months in two prospective clinical trials. Outcomes include adverse events, growth, hemoglobin and serum iron, glucose levels, HbA1c, CD4+ lymphocytes, and bone mineral density.ResultsSixty-eight patients completed a minimum of 2 years of treatment with EryDex (mean treatment length 39 ± 11 months). Treatment-emergent adverse events (TEAE), reported in 67 (99%) out of 68 patients, were typically mild and did not cause discontinuation of treatment or death. Treatment-related TEAE were noted in 48 (71%) patients. Notable adverse events included transient pruritus reported in 23 (34%) patients and findings of low serum iron reported in 27 (40%) patients, while at baseline one fifth of patients had low serum iron. Anemia was reported in 9 (13%) patients. The mean hemoglobin level changed by −0.8 ± 1.0 g/dL after 6 months of therapy without subsequent decline. Longitudinal height and weight mean z-scores showed minimal change from baseline to month 24 for height (−0.06 ± 0.49), weight (−0.02 ± 0.71), and body mass index (0.03 ± 0.87). The mean bone mineral density (BMD) z-score showed a decline of 0.4 points over the 24 months of treatment. Values for glucose, HbA1c, cortisol, and CD4+ lymphocyte counts did not show clinically significant changes during prolonged treatment with EryDex.ConclusionThe most common treatment-related adverse events were transient infusion-related pruritus and iron deficiency. There was a decline in BMD which could not be distinguished from the natural course of disease. There were no adverse effects on height, weight and body mass index noted, as documented by stable z-scores throughout the 2 years of treatment. Adverse events typically observed with prolonged glucocorticoid use such as Cushingoid features, weight gain, hypertension, hirsutism, diabetes or stunted growth were rarely reported.Clinical trial registrationClinicalTrials.gov, identifiers: NCT02770807 and NCT03563053.
Chemical characterization and encapsulation of Ganoderma pfeifferi extract with cytotoxic properties
Authors: Šťastný Jan , Morellá-Aucejo Ángela , Skala Tomáš , Bernardos Andrea , Maršík Petr , Lérida-Viso Araceli , Matějka Jaroslav , Mascellani Bergo Anna , Marcos María Dolores , Martínez-Máñez Ramón , Jablonský Ivan , Klouček Pavel 
Published: January 2025

Mushrooms of the genus Ganoderma are known for diverse biological activities, demonstrated both traditionally and experimentally. Their secondary metabolites have shown cytotoxic potential across different cancer cell lines. Besides exploration of the most active components in different species or genotypes, new formulation techniques are in development. In recent years, there has been a growing interest in the use of nanomaterials because of significant potential for pharmacology applications as substance carriers. Applying nanoparticles may enhance the medicinal effect of the mushroom substances. This study investigated the cytotoxic properties of Ganoderma species methanolic extracts against the HeLa cancer cell line. Notably, the extract obtained from Ganoderma pfeifferi demonstrated the highest activity and was further used for encapsulation within synthesized mesoporous silica nanoparticles MCM-41. Subsequently, the cytotoxic effect of the loaded MCM-41 to the free form of extract was compared. The obtained results indicate successful encapsulation, and similar activity comparing encapsulated form to free extracts (IC50 16.6 μg/mL and 20.5 μg/mL, respectively). In addition, the four unique compounds were identified as applanoxidic acid A, applanoxidic acid G, ganoderone A, and ganoderone B in the G. pfeifferi. This study is an essential prerequisite for further steps like nanoparticle functionalization for sustained or on-command delivery of these natural extracts.
Impact of sand and dust storms on mortality in Jinan City, China
Authors: Shen Chaofan , Li Mingjun , Wang Qingchang , Luan Jinjiao , Si Jiliang , Cui Liangliang 
Published: January 2025

BackgroundSand and dust storms (SDSs) cause considerable health risks worldwide. China is a country seriously affected by SDSs, however only few studies researched the risk of SDS in China. The insufficient evidence on SDS hampers effective measures to mitigate its harm.ObjectiveTo reveal the mortality risks associated with SDSs in Jinan City and identify sensitive populations vulnerable to these events.MethodsFor this time-stratified case-crossover study, we collected daily data on all-cause, circulatory, and respiratory deaths, as well as air pollution and meteorological information from Jinan City in China between January 1, 2013, and November 30, 2022. We initially utilized a time-stratified case-crossover design and logistic regression model to examine the short-term relationship between SDSs and mortality risks, adjusting for specific variables such as mean temperature, humidity, wind speeds, and holidays. Subsequently, we conducted stratified analyses by age, gender, and season.ResultsA total of 53 SDSs were observed, lasting for 88 days during the study period, which accounted for 2% of the study period. The excess mortality risks associated with SDSs were 13% (95% CI: 4–22%), 4% (95% CI: 1–8%), and 3% (95% CI: 1–6%) for respiratory, circulatory, and all-cause death, respectively. Females and people over 65 years of age are vulnerable to respiratory deaths caused by SDSs.ConclusionShort-term exposure to SDSs caused the significantly elevated risks of respiratory, circulatory and all-cause death. Females and individuals over the age of 65 are particularly vulnerable to the effects of SDSs.
Income-related inequalities in the prevalence of dental pain intensity in adults: gender differences
Authors: Lima Carolina Veloso , de Arruda Alanna Barros , Noronha Mayara dos Santos , Sampaio Aline Araujo , Silveira Marise Fagundes , Martins Andrea Maria Eleuterio de Barros Lima , Ferreira Raquel Conceição , de Godoy Aline Netto , Sousa Daniela Marques da Silva , Garcia Patrick Pereira , Costa Cyrene Piazera Silva , Souza João Gabriel Silva , Costa Oliveira Bárbara Emanoele 
Published: January 2025

IntroductionDental pain is a multifactorial and unpleasant experience that negatively affects daily activities. Previous studies have shown that adults living in socioeconomically disadvantaged areas showed higher dental pain prevalence. This study evaluated whether income inequalities are related to increased dental pain intensity among adults and identified differences between women and men.MethodsA probabilistic sample of adults was investigated, and income inequality was evaluated using the Gini Index. Dental pain intensity was recorded on a scale from 1–10 for those who experienced dental pain in the 6 months preceding the survey. The covariates were contextual (related to cities) and individual (related to individuals). Associations were investigated for the entire sample and stratified by gender using multilevel Poisson regression models.ResultsDental pain was reported by 41% of the included sample (n = 4,512 adults). Maximum pain intensity was reported more frequently for women than for men. Those living in municipalities with higher Gini Index values reported 1.26 times (95% CI: 1.01–1.56) greater dental pain intensity compared to adults living in cities with lower Gini Index values, even after adjustment by variables. The same pattern was observed when stratified by gender, but it was not statistically significant.ConclusionThus, the contexts of income inequalities can contribute to more severe dental pain intensity among adults. Also, the findings suggest that income inequality does not modify the relationship between gender and dental pain intensity.
Exploring SLEEPINESS through home monitoring with ultra-long-term subcutaneous EEG and ecological momentary assessment in sleepy treatment naïve obstructive sleep apnea patients starting CPAP treatment—A study protocol article
Authors: Sarkez-Knudsen Mathias , Ballegaard Martin , Piilgaard Henning , Ahrens Esben , Hemmsen Martin Christian , Andersen Tobias Søren , Bradram Jakob Eyvind , Homøe Preben 
Published: January 2025

IntroductionExcessive daytime sleepiness (EDS) is a key symptom for patients with obstructive sleep apnea (OSA). Despite important limitations in the longitudinal monitoring of EDS, the Epworth Sleepiness Scale (ESS), the Maintenance of Wakefulness Test, and the Multiple Sleep Latency Test (MSLT) are the best available objective tests to predict EDS. Limited information exists on the day-to-day fluctuations of sleepiness symptoms from the everyday life perspective of OSA patients. The most feared is sudden sleep episodes that cause traffic accidents. The following study protocol investigates the novel possibilities of ultra-long-term Electroencephalography (EEG) (ULT-EEG) home monitoring in sleepy OSA patients with a subcutaneous implant. We hypothesize that the high-frequency testing from ULT-EEG, in combination with an ecological momentary assessment (EMA), can provide the information to develop new electrophysiological monitoring of sleep propensity as an alternative to the well-established, yet subjective, ESS.MethodsThis clinical exploratory and experimental study will include 15 treatment-naïve patients with severe OSA, with a baseline ESS score above 10. The subjects will be implanted with a two-channel subcutaneous EEG monitoring device upon inclusion and a confirmative polysomnography MSLT. Subcutaneous EEG is recorded 24/7 for 6 weeks before and 6 weeks during continuous positive airway pressure (CPAP) treatment. Daily assessments with the Karolinska Sleepiness Scale, the Psychomotor Vigilance Task test, and a sleep/nap diary will be collected using EMA methods.DiscussionThis study combines data collection from sleepy OSA patients' natural environments using ULT-EEG and EMA methods to obtain sleepiness metrics suitable for developing and preliminarily validating the possibilities of ULT-EEG sleepiness monitoring. We aim to prove a new concept of monitoring sleepiness symptoms in OSA patients and gain new insights into CPAP-related sleepiness rehabilitation.Ethics and disseminationAll participants will provide written informed consent to participate in this study. Ethical approval from the Region Zealand Ethics Committee on 13/09/2021 (SJ939, EMN-2021-06803). The study will be conducted in accordance with local legislation and institutional requirements and comply with the Declaration of Helsinki and the General Data Protection Regulation (GDPR).
First microscopic and molecular identification of Cryptosporidium spp. in fat sand rats (Psammomys obesus) in Egypt and their potential zoonotic implications
Authors: Mohamed Sara Abdel-Aal , Anwar Fatma A. S. , Gareh Ahmed , Ghallab Marwa M. I. , Martínez Remigio , Gouda Asmaa Aboelabbas , Alajmi Fatemah Enad , Alzaylaee Hind , García-Bocanegra Ignacio , Elmahallawy Ehab Kotb 
Published: January 2025

IntroductionRodents, thriving in human-altered environments, pose significant public health risks due to their role as reservoirs for numerous zoonotic parasites. Among these, Cryptosporidium spp. are recognized globally as leading causes of waterborne and foodborne diarrheal illnesses in humans. The specific role of fat sand rats (Psammomys obesus) in the transmission of Cryptosporidium spp. in Egypt and the genotypic characteristics of the circulating species in these animals remain poorly understood.MethodsIn this study, a total of 150 individual fat sand rat stool samples were collected from the saline marsh periurban areas of Abu-Rawash, Giza, Egypt. The samples were initially screened for the presence of Cryptosporidium spp. using light and scanning electron microscopy to characterize the parasite’s oocysts. Furthermore, molecular identification and characterization of the parasite were carried out on selected microscopy-positive samples (n = 30) using conventional polymerase chain reaction (PCR) targeting the Cryptosporidium oocyst wall protein (COWP) gene. A subset of these positive samples by PCR was subjected to sequencing, with the resulting sequences deposited in GenBank™ and analyzed through phylogenetic methods.ResultsConventional microscopy revealed that 46.7% (70/150; 95% CI: 38.7–54.6) of the analyzed stool samples contained structures consistent with Cryptosporidium oocysts. Moreover, the molecular analysis confirmed Cryptosporidium species in DNA from all 30 stool samples previously identified as heavily infected through microscopy. Notably, the phylogenetic analysis identified Cryptosporidium parvum (C. parvum) in the sequenced samples, likely originating from the rats’ native habitats. These identified species have been deposited in GenBank™ under the accession numbers OM817461 (C. parvum FSA-1), OM817462 (C. parvum FSA-2), and OM817463 (C. parvum FSA-3) and revealed closed genetic identity with those species reported from human and other animal species in the same geographic location.ConclusionOverall, this study represents the first morphological and genetic identification of C. parvum isolated from fecal samples of fat sand rats trapped from periurban areas in Egypt. These findings provide valuable insights into the potential zoonotic implications of rodents in disease transmission at the national level, offering crucial information for public health awareness campaigns and informing local authorities.