bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphology control of conjugated microporous polymer networks for visible‐light‐driven oxidative coupling of amines
Authors: Jiang Sheng Hong , Li Xue , Zhang Xi Juan , Ding Qiong , Cai Tao 
Published: November 2023

AbstractMorphology control of conjugated microporous polymer networks (CMPs) has emerged as a promising strategy for enhancing catalytic efficiency and alleviating product contamination in photocatalytic organic transformations. In this contribution, we present the rational design and synthesis of hollow CMPs (hPorSTZ and hPorDTZ) featuring benzothiadiazoles linkages via Sonogashira‐Hagihara cross‐coupling reaction onto the surface of SiO2 microspheres, followed by the elimination of the SiO2 inner templates. By comparing the catalytic performance of hollow and nonhollow materials, we demonstrated the impact of substrate diffusion pathway on visible‐light‐driven oxidative coupling of amines to imines. With a larger specific surface area and variable surface catalytically active sites, the hollow CMPs exhibited efficient reusability, which reduced the consumption of precious resources and achieve faster conversion rates while maintaining reliable recyclability, competing with their nonhollow counterparts. This morphology‐controlled strategy outlines a promising route for diverse organic transformations utilizing stable, efficient, and recyclable metal‐free CMPs.
Distribution, frequency and molecular basis of clethodim and quizalofop resistance in brome grass (Bromus diandrus)
Authors: Busi Roberto , Goggin Danica , McKenna Nicholas , Taylor Candy , Runge Fabian , Mehravi Shagheyegh , Porri Aimone , Batley Jacqueline , Flower Ken 
Published: November 2023

AbstractBACKGROUNDBrome grass (Bromus diandrus Roth) is prevalent in the southern and western cropping regions of Australia, where it causes significant economic damage. A targeted herbicide resistance survey was conducted in 2020 by collecting brome grass populations from 40 farms in Western Australia and subjecting these samples to comprehensive herbicide screening. One sample (population 172‐20), from a field that had received 12 applications of clethodim over 20 years of continuous cropping, was found to be highly resistant to the acetyl‐CoA carboxylase (ACCase)‐inhibiting herbicides clethodim and quizalofop, and so the molecular basis of resistance was investigated.RESULTSAll 31 individuals examined from population 172‐20 carried the same resistance‐endowing point mutation causing an aspartate‐to‐glycine substitution at position 2078 in the translated ACCase protein sequence. A wild‐type susceptible population and the resistant population had similar expression levels of plastidic ACCase genes. The level of resistance to quizalofop, either standalone or in mixture with clethodim, in population 172‐20 was lower under cooler growing conditions.CONCLUSIONTarget‐site resistance to ACCase‐inhibiting herbicides, conferred by one ACCase mutation, was selected in all tested brome plants infesting a field with a history of repeated clethodim use. This mutation appears to have been fixed in the infesting population. Notably, clethodim resistance in this population was not detected by the farmer, and a high future incidence of quizalofop resistance is anticipated. Herbicide resistance testing is essential for the detection of evolving weed resistance issues and to inform effective management strategies. © 2023 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Integral sliding mode‐based event‐triggered nearly optimal tracking control for uncertain nonlinear systems
Authors: Zhang Shunchao , Wang Yonghua , Liu Dacai , Zhuang Jiawei , Zhang Yongwei 
Published: November 2023

SummaryIn this paper, an event‐triggered nearly optimal tracking control method is investigated for a class of uncertain nonlinear systems by integrating adaptive dynamic programming (ADP) and integral sliding mode (ISM) control techniques. An ISM‐based discontinuous control law with a neural network (NN) adaptive term is designed to eliminate the influence of the uncertainties and obtain the sliding mode dynamics which is equivalent to the tracking error dynamics without uncertainties, and relax the known upper‐bounded condition of uncertainties. In order to guarantee the stability of tracking error system and the considerable optimality, under the ADP technique, a critic NN is applied to approximate the optimal value function for solving the event‐triggered Hamilton‐Jacobi‐Bellman equation and the event‐triggered nearly optimal feedback control is obtained. The feedback control law is updated and transmitted to plant only when events occur, thus both the communication and the computational resources can be saved. Furthermore, the stability of tracking error is proven thanks to Lyapunov's direct method. Finally, we provide two simulation examples to validate the developed control scheme.
Synthesis, XRD/HSA‐Interactions, QTAIM Analysis, Optical and Nonlinear Optical Responses Studies of Cu(II) Complex with the Schiff Base Ligand Derived from 5‐Bromosalicylaldehyde
Authors: Lamiri Wafa , Djaafer‐Moussa Raziqa , Merabet Layachi , Setifi Fatima , Kaboub Lakhemici , Hannachi Douniazed 
Published: November 2023

AbstractIn this study, we efficiently synthesized a new Schiff base ligand (H2L) along with its mononuclear complex Cu(II) (1). The chemical structures of these compounds were rigorously determined using various analytical techniques, including UV‐ Vis., FT‐IR, 1H NMR, 13 C NMR CHN elemental analysis, single crystal X‐ray diffraction, and quantum calculations. The X‐ray diffraction analysis of the complex revealed the presence of intermolecular interactions characterized by C−H…Br hydrogen bonds, leading to the formation of 2D layers. We conducted a systematic investigation of these intermolecular interactions using HS and QTAIM analysis. Additionally, we affected a comprehensive analysis of H2L, 1, and 2, focusing on their structural, electronic, and optical properties using DFT and TD‐DFT calculations in gas and solvent. The computed parameters closely matched the experimental data, demonstrating good agreement. Reactivity parameters indicated that complex 2 exhibited lower hardness (~1.7 eV) compared to 1 (~1.8 eV) and H2L (~4.4 eV). NLO analysis revealed substantial α and β values for compound 2 in both static and dynamic regimes. Notably, the β values of the title complexes increased with higher solvent polarity. In summary, our investigation highlights the potential of the title complexes as promising candidates for second‐order nonlinear optical materials.
A New Efficient Method for the Synthesis of Fused [1,2,5]Thiadiazoles and Their Dearomatization with C‐Nucleophiles
Authors: Fedorenko Alexey K. , Ivanova Victoria V. , Minyaev Mikhail E. , Bastrakov Maxim A. , Starosotnikov Alexey M. 
Published: November 2023

AbstractGeneral method for the annulation of [1,2,5]thiadiazole ring to pyridine and benzene cycle has been developed using sulfur monochloride as a sulfur source. On this basis a number of [1,2,5]thiadiazolo[4,3‐b]pyridines and benzo[c]thiadiazoles were synthesized. The most π‐deficient [1,2,5]thiadiazolo[4,3‐b]pyridines readily react with neutral carbon nucleophiles such as CH‐acids, indoles, pyrrole and phloroglucinol to give 1,4‐adducts.
Synthesis of Silver Nanoparticles from Silver Closo‐Dodecaborate Film for Enhanced Hydrogen Evolution
Authors: Khan Majharul Haque , Han Chao , Wang Xuefei , Li Weijie , Zhang Guojin , Huang Zhenguo 
Published: November 2023

AbstractThe icosahedral closo dodecaborate cluster [B12H12]2− is gaining increasing interest due to its unique properties including the ease of functionalization, 3D aromaticity, and formation of metal salts with high ion conductivity. In this work, simple and effective preparation of silver closo dodecaborte (Ag2B12H12) films is reported by an electrochemical route. The size of the Ag2B12H12 particles in the films can be tuned from nanometers to micrometers by varying the electrochemical parameters. Ag nanoclusters with controllable sizes are successfully generated via electrochemical reduction reactions or thermal anneal of the Ag2B12H12 films. When tested for hydrogen evolution reaction (HER) in an acidic solution, the as‐prepared Ag nanoparticles deliver a current density of 10 mA cm−2 at 376 mV overpotential. This research sheds light on a new synthesis of [B12H12]2− based thin films, the generation of metal nano‐powders, and their application in HER or other applications.
Dopant Engineering of Hafnia‐Based Ferroelectrics for Long Data Retention and High Thermal Stability
Authors: Kim Ik‐Jyae , Lee Jang‐Sik 
Published: November 2023

AbstractHafnia‐based ferroelectrics have gained much attention because they can be used in highly scaled, advanced complementary metal‐oxide semiconductor (CMOS) memory devices. However, thermal stability should be considered when integrating hafnia‐based ferroelectric transistors in advanced CMOS devices, as they can be exposed to high‐temperature processes. This work proposed that doping of Al in hafnia‐based ferroelectric material can lead to high thermal stability. A ferroelectric capacitor based on Al‐doped hafnia, which can be used for one‐transistor‐one‐capacitor applications, exhibits stable operation even after annealing at 900 °C. Moreover, it demonstrates that the ferroelectric transistors based on Al‐doped hafnia for one‐transistor applications, such as ferroelectric NAND, retain their memory states for 10 years at 100 °C. This study presents a practical method to achieve thermally stable ferroelectric memories capable of enduring high‐temperature processes and operation conditions.
Colorimetric Detection of HER2‐Overexpressing‐Cancer‐Derived Exosomes in Mouse Urine Using Magnetic‐Polydiacetylene Nanoparticles
Authors: Kim Ryunhyung , Mun Byeonggeol , Lim Seongjae , Park Chaewon , Kim Jinyoung , Lim Jaewook , Jeong Hyein , Son Hye Young , Rho Hyun Wook , Lim Eun‐Kyung , Haam Seungjoo 
Published: November 2023

AbstractBreast cancer (BC) is a major global health problem, with ≈20–25% of patients overexpressing human epidermal growth factor receptor 2 (HER2), an aggressive marker, yet access to early detection and treatment varies across countries. A low‐cost, equipment‐free, and easy‐to‐use polydiacetylene (PDA)‐based colorimetric sensor is developed for HER2‐overexpressing cancer detection, designed for use in low‐ and middle‐income countries (LMICs). PDA nanoparticles are first prepared through thin‐film hydration. Subsequently, hydrophilic magnetic nanoparticles and HER2 antibodies are sequentially conjugated to them. The synthesized HER2‐MPDA can be concentrated and separated by a magnetic field while inheriting the optical characteristics of PDA. The specific binding of HER2 antibody in HER2‐MPDA to HER2 receptor in HER2‐overexpressing exosomes causes a blue‐to‐red color change by altering the molecular structure of the PDA backbone. This colorimetric sensor can simultaneously separate and detect HER2‐overexpressing exosomes. HER2‐MPDA can detect HER2‐overexpressing exosomes in the culture medium of HER2‐overexpressing BC cells and in mouse urine samples from a HER2‐overexpressing BC mouse model. It can selectively isolate and detect only HER2‐overexpressing exosomes through magnetic separation, and its detection limit is found to be 8.5 × 108 particles mL−1. This colorimetric sensor can be used for point‐of‐care diagnosis of HER2‐overexpressing BC in LMICs.
Nanoengineered Macrophages Armed with TLR7/8 Agonist Enhance Remodeling of Immunosuppressive Tumor Microenvironment
Authors: Yoo Yeon Jeong , Eun Ryounho , Park Hye Min , Kim Suhyeon , Park Sei Hyun , Heo Janghun , Lim Yong Taik 
Published: November 2023

AbstractAlthough adoptive cell‐based therapy is illuminated as one of the promising approaches in cancer immunotherapy, it shows low antitumor efficacy because transferred cells adapt and alter toward a pro‐tumoral phenotype in response to the tumor's immunosuppressive milieu. Herein, nanoengineered macrophages anchored with functional liposome armed with cholesterol‐conjugated Toll‐like receptor 7/8 agonist (masked TLR7/8a, m7/8a) are generated to overcome the shortcomings of current macrophage‐based therapies and enhance the remodeling of the immunosuppressive tumor microenvironment (TME). The liposome‐anchored macrophages (LAMΦ‐m7/8a), are fabricated by anchoring dibenzocyclooctyne‐modified liposome(m7/8a) onto azido‐expressing macrophages via a bio‐orthogonal click reaction, are continuously invigorated due to the slow internalization of liposome(m7/8a) and sustained activation. LAMΦ‐m7/8a secreted ≈3 and 33‐fold more IL‐6 and TNF‐α than conventional M1–MΦ, maintained the M1 phenotype, and phagocytosed tumor cells for up to 48 h in vitro. Both intratumoral and intravenous injections of LAMΦ‐m7/8a induced effective antitumor efficacy when treated in combination with doxorubicin‐loaded liposomes in 4T1‐tumor bearing mice. It not only increases the infiltration of antigen‐specific CD8+ T cells secreting granzyme B, IFN‐γ, and TNF‐α within the TME, but also reduces myeloid‐derived suppressor cells. These results suggest that LAMΦ‐m7/8a may provide a suitable alternative to next‐generation cell‐based therapy platform.
Pancreatic cancer cell line in responsive hydrogel microcapsules for drug evaluation
Authors: Song Taiyu , Zhang Hui , Liu Guangling , Qiu Yudong , Wang Huan 
Published: November 2023

AbstractDrug therapies are the cornerstone of systemic treatment for pancreatic cancer patients. However, the relative outcome of drug evaluation is often hampered by the complex microenvironment of pancreatic cancer due to the lack of reasonable tumor models. Here, we proposed a novel platform that integrated pancreatic adenocarcinoma cells encapsulated into hydrogel microcapsules for three‐dimensional (3D) tumor cultivation and antitumor agent evaluation. These hydrogel microcapsules contain alginate/poly (N‐isopropyl acrylamide) (alginate/PNIPAM) shells and carboxymethyl cellulose cores, which are generated through the microfluidic electrospray technique. The microcapsules have the feature of rapid response to temperature, by which they can regulate the internal pressure environment. Besides, benefiting from good monodispersity, precise size control, and biocompatibility of these microcapsules, these wrapped tumor cells have the capacity for proliferating spontaneously and forming 3D tumor spheroids with good cell viability. We have demonstrated that pancreatic adenocarcinoma cells encapsulated in the composite microcapsules with different PNIPAM concentrations showed different drug sensitivity, which could be ascribed to the influence of external pressures environment. These results indicate that the tumor spheroids coated in these responsive microcapsules have great potential in the analysis of antitumor drug sensitivity.
Ventricular fibrillation in a dog with refractory hyperkalaemia due to uroabdomen following extradural anaesthesia
Authors: Hordle Thomas , Niimura Del Barrio Maria Chie , Michou Joanne 
Published: November 2023

AbstractA young adult, crossbreed dog was presented to a referral small animal veterinary hospital with uroabdomen causing a severe hyperkalaemia. Stabilisation of the condition consisted of abdominocentesis and intravenous administration of calcium gluconate, insulin, glucose and crystalloids. The patient was then anaesthetised for diagnostic and therapeutic procedures. An epidural was performed with levobupivacaine due to nociception and requirement for exploratory surgery. Marked bradycardia ensued and was treated with anticholinergics and terbutaline, among other repeated efforts to resolve a pharmaceutically resistant hyperkalaemia. However, cardiorespiratory arrest followed, characterised by ventricular fibrillation. Cardiopulmonary resuscitation utilised cardioversion to achieve return of spontaneous circulation within 16 minutes. After return of spontaneous circulation, serum potassium levels only decreased and remained below 7 mmol/L after repeat abdominocentesis, alongside continued medical therapy. Unfortunately, despite successful recovery from general anaesthesia, the patient later developed surgical wound dehiscence and was euthanased as a result.
Introduction
Authors: Jóhannesson Gunnar Thór , Lund Katrín Anna , Thorsteinsson Björn , Jóhannesdóttir Guðbjörg R. 
Published: November 2023

AbstractThis book examines places on the margins and the dynamics through which a marginal position of a place is created. Specifically, it explores how places, mostly in sparsely populated areas, often perceived as immobile and frozen in time, come into being and develop through interference of everyday mobilitiesand creative practices that cut across the spheres of culture and nature as usually defined.
Melrakkaslétta the Meeting-Ground: Performing Qualitative Research at the Tourism Margin
Authors: Barðadóttir Þórný 
Published: November 2023

AbstractThis chapter follows the journey of a doctoral research project from the setting of a research agenda, a theoretical framework and a methodological approach to conducting research on site. The research sets focus on Melrakkaslétta, a rural area on the Icelandic northeast coast. Melrakkaslétta is situated far north of the beaten Icelandic tourism track and has as such mostly been bypassed by the recent global tourism boom. This, however, does not mean that Melrakkaslétta is an immobile place as it has for centuries been inhabited and visited by humans and other beings.The research design is set within a qualitative research paradigm, where through flat ontology and a post-ANT lens, ethnographic methodology is applied with the aim of co-creating knowledge with the humans and the more-than-human world of Melrakkaslétta. The chapter explores the decisions and reasoning for the research, where the aim is to inspect tourism in a non-touristy, rural area, with the agenda of avoiding perceiving the margin either as a rural idyll or a site of rural hardship, decline and struggle. Instead, at the core is the assumption that in Melrakkaslétta, as elsewhere in the world, joy and well-being occur amongst the various challenges of any existence.
NNLL resummation of Sudakov shoulder logarithms in the heavy jet mass distribution
Authors: Bhattacharya Arindam , Michel Johannes K. L. , Schwartz Matthew D. , Stewart Iain W. , Zhang Xiaoyuan 
Published: November 2023

Abstract
The heavy jet mass event shape has large perturbative logarithms near the leading order kinematic threshold at $$ \rho =\frac{1}{3} $$
ρ
=

1
3

. Catani and Webber named these logarithms Sudakov shoulders and resummed them at double-logarithmic level. A resummation to next-to-leading logarithmic level was achieved recently. Here, we extend the resummation using an effective field theory framework to next-to-next-to-leading logarithmic order and show how to combine it with the resummation of dijet logarithms. We also solve the open problem of an unphysical singularity in the resummed momentum space distribution, in a way similar to how it is resolved in the Drell-Yan qT spectrum: through a careful analysis of the kinematics and scale-setting in position space. The heavy jet mass Sudakov shoulder is the first observable that does not involve transverse momentum for which position space resummation is critical. These advances may lead to a more precise extraction of the strong coupling constant from e+e− data.
Caught in the moment: interaction of immiscible carbonate and sulfide liquids in mafic silicate magma—insights from the Rudniy intrusion (NW Mongolia)
Authors: Cherdantseva Maria , Vishnevskiy Andrey , Jugo Pedro J. , Martin Laure A. J. , Aleshin Matvei , Roberts Malcolm P. , Shaparenko Elena , Langendam Andrew , Howard Daryl L. , Fiorentini Marco L. 
Published: November 2023

AbstractThe Devonian Rudniy intrusion is a composite magmatic body comprising two gabbroid units. Located in the Tsagaan-Shuvuut ridge in NW Mongolia, it is the only one known to contain disseminated sulfide Ni-Cu-PGE minerals out of numerous gabbroid intrusions surrounding the Tuva depression. The ore occurs as disseminated sulfide globules made of pyrrhotite, pentlandite, chalcopyrite, and cubanite, confined to a narrow troctolitic layer at the margins of a melanogabbro, at the contact with a previously emplaced leucogabbro. Globules generally display mantle-dominated sulfur isotopic signatures but show variable metallogenic and mineralogical characteristics, as well as notably different sizes and morphologies reflecting variable cooling and crystallization regimes in different parts of the intrusion. Sulfides from the chilled margin of the melanogabbro are surrounded and intergrown with volatile-rich (i.e., CO2-, H2O-, F-, and Cl) phases such as calcite, chlorite, mica, amphibole, and apatite. Based on the mineralogical and textural relationships of volatile-rich phases with sulfides, we argue that this assemblage represents the product of the crystallization of volatile-rich carbonate melt immiscible with both silicate and sulfide liquids. We put forward the hypothesis that volatile-rich carbonate melt envelops sulfide droplets facilitating their transport in magmatic conduits and that this process may be more widespread than commonly thought. The smaller sulfide globules, which are interpreted to derive from the breakup of larger globules during transport and emplacement, do not display an association with volatile-rich phases, suggesting that the original carbonate melt could have been detached from them during the evolution of the magmatic system. Variable rates of crystallization may have been responsible for the observed disparities in the mineralogical and metallogenic characteristics of different sulfide globules entrained in the Rudniy intrusion.
Trabekulotomie (ab externo) als Ersteingriff bei Offenwinkelglaukomen
Authors: Bornhauser Marco , Neuhann Lukas , Neuhann Thomas , Maier Mathias 
Published: November 2023

Zusammenfassung
Hintergrund
Die Ergebnisse der Trabekulotomie ab externo (TOT) als nicht fistulierende drucksenkende Operation bei Erwachsenen mit Offenwinkelglaukom sind im Vergleich zu anderen drucksenkenden Operationen nur wenig beschrieben.

Ziel der Arbeit
Ermittlung der langzeitigen drucksenkenden Wirkung und Komplikationen der TOT als Stand-alone-Eingriff oder in Kombination mit einer Phakoemulsifikation mit Intraokularlinsenimplantation (PIT) als primärer drucksenkender Eingriff bei erwachsenen Patienten mit Formen des chronischen Offenwinkelglaukoms.

Methodik
Es handelt sich um eine retrospektive Analyse von 121 Augen von 106 Patienten. Bei 90 Augen wurde eine TOT und bei 31 Augen eine PIT durchgeführt. Der Nachbeobachtungszeitraum betrug 5 Jahre. Die gesamte Nachbeobachtung erfolgte im gleichen Zentrum unter standardisierten Bedingungen. Es wurden präoperativ sowie postoperativ der bestkorrigierte Fernvisus, Intraokulardruck (IOD), drucksenkende Medikation sowie Komplikationen erfasst. Bei Erfolgskriterium 1 durfte der IOD bei keiner Kontrolle über 17 mm Hg sein. Bei Erfolgskriterium 2 durfte der IOD bei einer Kontrolle im gesamten Nachbeobachtungszeitraum über 17 mm Hg sein.

Ergebnisse
Präoperativer IOD in der TOT-Gruppe: 25,92 mm Hg (SD 6,58) und 26,32 mm Hg (SD 6,06) in der PIT-Gruppe. Die jährlichen kumulativen Erfolgsraten mit drucksenkenden Medikamenten bei Erfolgskriterium 1 sind: 92,8 %, 82,5 %, 70,5 %, 52,7 % und 26,1 %. Bei Erfolgskriterium 2 sind diese: 97,9 %; 94,9 %, 93,2 %, 91,3 % und 89 %. Es bestand kein relevanter Unterschied in der Drucksenkung zwischen der TOT und PIT. Ohne drucksenkende Medikamente sind die Erfolgsraten bei beiden Erfolgskriterien deutlich niedriger. Es traten keine schwerwiegenden Komplikationen auf. Die häufigste postoperative Komplikation war ein spontan resorbierbares Hyphäma.

Diskussion
Die Durchführung einer TOT oder PIT als primärer drucksenkender Eingriff bei chronischen Offenwinkelglaukomen bei Erwachsenen ist sinnvoll und von signifikantem drucksenkendem Effekt und sehr geringer Komplikationsrate.