bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atmospheric Rivers in Southeast Alaska: Meteorological Conditions Associated With Extreme Precipitation
Authors: Nash Deanna , Rutz Jonathan J. , Jacobs Aaron 
Published: February 2024

AbstractExtreme precipitation events associated with atmospheric rivers (ARs) trigger floods, landslides, and avalanches that threaten lives and livelihoods in Southeast Alaska. Six rural and indigenous communities (Hoonah, Klukwan, Skagway, Yakutat, Craig, and Kasaan) identified specific needs regarding these hazards and joined the Southeast Alaska Coastlines and People (CoPe) Kutí Hub to address the shared challenge of understanding and predicting these events. This study presents a climatology (1980–2019) of synoptic, mesoscale, and local meteorological characteristics of ARs and heavy precipitation across this region. High‐amplitude upper‐level patterns across the northeastern Pacific Ocean favor ARs reaching Southeast Alaska, where moisture is orographically lifted, resulting in heavy precipitation. In the six communities, ARs occur 8–15 days per month, yet only 6 AR days per year account for up to 68%–91% of precipitation extremes. Furthermore, 80%–96% of days with extreme precipitation have >75th percentile integrated water vapor transport (IVT), demonstrating the strong relationship between IVT and extreme precipitation. This study also highlights the relationship between IVT direction and complex coastal topography in determining precipitation extremes. For example, in Klukwan and Skagway, 80%–90% of extreme AR days have south‐southwesterly or south‐southeasterly IVT. Coastal communities like Yakutat experience higher IVT and precipitation overall, and although southeasterly IVT is more common, extreme precipitation events are most common with southwesterly IVT. Collaboration with the National Weather Service in Juneau, Alaska will lead to improved situational awareness, forecasts, and Impact Decision Support Services to communities, saving lives and property in a region vulnerable to the impacts of climate change.
Constraints on the Spatial Distribution of Lunar Crustal Magnetic Sources From Orbital Magnetic Field Data
Authors: Oliveira Joana S. , Vervelidou Foteini , Wieczorek Mark A. , Díaz Michelena Marina 
Published: February 2024

AbstractSpacecraft measurements show that the crust of the Moon is heterogeneously magnetized. The sources of these magnetic anomalies are yet not fully understood, with most not being related to known geological structures or processes. Here, we use an inversion methodology that relies on the assumption of unidirectional magnetization, commonly referred to as Parker's method, to elucidate the origin of the magnetic sources by constraining the location and geometry of the underlying magnetization. This method has been used previously to infer the direction of the underlying magnetization but it has not been tested as to whether it can infer the geometry of the source. The performance of the method is here assessed by conducting a variety of tests, using synthetic magnetized bodies of different geometries mimicking the main geological structures potentially magnetized within the lunar crust. Results from our tests show that this method successfully localizes and delineates the two‐dimensional surface projection of subsurface three‐dimensional magnetized bodies, provided their magnetization is close to unidirectional and the magnetic field data are of sufficient spatial resolution and reasonable signal‐to‐noise ratio. We applied this inversion method to two different lunar magnetic anomalies, the Mendel‐Rydberg impact basin and the Reiner Gamma swirl. For Mendel‐Rydberg, our analysis shows that the strongest magnetic sources are located within the basin's inner ring, whereas for Reiner Gamma, the strongest magnetic sources form a narrow dike‐like body that emanates from the center of the Marius Hills volcanic complex.
Local Volume Solvers for Earth System Data Assimilation: Implementation in the Framework for Joint Effort for Data Assimilation Integration
Authors: Frolov Sergey , Shlyaeva Anna , Huang Wei , Sluka Travis , Draper Clara , Huang Bo , Martin Cory , Elless Travis , Bhargava Kriti , Whitaker Jeff 
Published: February 2024

AbstractThe Joint Effort for Data assimilation Integration (JEDI) is an international collaboration aimed at developing an open software ecosystem for model agnostic data assimilation. This paper considers implementation of the model‐agnostic family of the local volume solvers in the JEDI framework. The implemented solvers include the Local Ensemble Transform Kalman Filter (LETKF), the Gain form of the Ensemble Transform Kalman Filter (GETKF), and the optimal interpolation variant of the LETKF (LETKF‐OI). This paper documents the implementation strategy for the family of the local volume solvers within the JEDI framework. We also document an expansive set of localization approaches that includes generic distance‐based localization, localization based on modulated ensemble products, and localizations specific to ocean (based on the Rossby radius of deformation), and land (based on the terrain difference between observation and model grid point). Finally, we apply the developed solvers in a limited set of experiments, including single‐observation experiments in atmosphere and ocean, and cycling experiments for the atmosphere, ocean, land, and aerosol assimilation. We also illustrate how JEDI Ensemble Kalman Filter solvers can be used in a strongly coupled framework using the interface solver approximation, which provides increments to the ocean based on observations from the ocean and atmosphere.
Calcareous Nannofossils and Paleoclimatic Evolution Across the Eocene‐Oligocene Transition at IODP Site U1509, Tasman Sea, Southwest Pacific Ocean
Authors: Viganò A. , Dallanave E. , Alegret L. , Westerhold T. , Sutherland R. , Dickens G. R. , Newsam C. , Agnini C. 
Published: February 2024

AbstractThe Eocene‐Oligocene transition (EOT; ∼34 Ma) was one of the most prominent global cooling events of the Cenozoic, coincident with the emergence of continental‐scale ice‐sheets on Antarctica. Calcareous nannoplankton experienced significant assemblage turnover at a time of long‐term surface ocean cooling and trophic conditions, suggesting cause‐effect relationships between Antarctic glaciation, broader climate changes, and the response of phytoplankton communities. To better evaluate the timing and nature of these relationships, we generated calcareous nannofossil and geochemical data sets (δ18O, δ13C and %CaCO3) over a ∼5 Myr stratigraphic interval recovered across the EOT from IODP Site U1509 in the Tasman Sea, South Pacific Ocean. Based on trends observed in the calcareous nannofossil assemblages, there was an overall decline of warm‐oligotrophic communities, with a shift toward taxa better adapted to cooler more eutrophic conditions. Assemblage changes indicate four distinct phases caused by temperature decrease and variations in paleocurrents: late Eocene warm‐oligotrophic phase, precursor diversity‐decrease phase, early Oligocene cold‐eutrophic phase, and a steady‐state cosmopolitan phase. The most prominent shift in the assemblages occurred during the ∼550 kyr‐long precursor diversity‐decrease phase, which has relatively high bulk δ18O and %CaCO3 values, and predates the phase of maximum glacial expansion (Earliest Oligocene Glacial Maximum–EOGM).
Ionospheric Disturbances Generated by the 2015 Calbuco Eruption: Comparison of GITM‐R Simulations and GNSS Observations
Authors: Tyska J. , Deng Y. , Zhang S. , Lin C. Y. 
Published: February 2024

AbstractVolcanic eruptions provide broad spectral forcing to the atmosphere and understanding the primary mechanisms that are relevant to explain the variety in waveform characteristics in the Ionosphere‐Thermosphere (IT) is still an important open question for the community. In this study, Global Navigation Satellite System (GNSS) Total Electron Content (TEC) data are analyzed and compared to simulations performed by the Global Ionosphere‐Thermosphere Model with Local Mesh Refinement (GITM‐R) for the first phase of the 2015 Calbuco eruption that occurred on 22 April. A simplified source representation and spectral acoustic‐gravity wave (AGW) propagation model are used to specify the perturbation at the lower boundary of GITM‐R at 100 km altitude. Two assumptions on the propagation structure, Direct Spherical (DS) and Ground Coupled (GC), are compared to the GNSS data and these modeling specifications show good agreement with different aspects of the observations for some waveform characteristics. Most notably, GITM‐R is able to reproduce the relative wave amplitude of AGWs as a function of radial distance from the vent, showing acoustic dominant forcing in the near field (<500 km) and gravity dominant forcing in the far‐field (>500 km). The estimated apparent phase speeds from GITM‐R simulations are consistent with observations with ∼10% difference from observation for both acoustic wave packets and a trailing gravity mode. The relevance of the simplifications made in the lower atmosphere to the simulated IT response is then discussed.
Skin color influences transcutaneous bilirubin measurements: a systematic in vitro evaluation
Authors: Dam-Vervloet Alida J. , Morsink Claudia F. , Krommendijk Marleen E. , Nijholt Ingrid M. , van Straaten Henrica L. M. , Poot Lieke , Bosschaart Nienke 
Published: February 2024

Abstract
Objective
Concerns have been raised about the effect of skin color on the accuracy of transcutaneous bilirubin (TcB) measurements, a widely used method for hyperbilirubinemia diagnosis in newborns. Literature is inconclusive, with both reported under- and overestimations of the TcB with increasing skin pigmentation. Therefore, the influence of skin color on TcB measurements was systematically evaluated in a controlled, in vitro setting.

Methods
A bilirubin meter (JM-105) was evaluated on layered phantoms that mimic neonatal skin with varying dermal bilirubin concentrations (0–250 µmol/L) and varying epidermal melanosome volume fractions (0–40%; light-dark skin color).

Results
TcB measurements were influenced by skin pigmentation. Larger mimicked melanosome volume fractions and higher bilirubin levels led to larger underestimations of the measured TcB, compared to an unpigmented epidermis. In the in vitro setting of this study, these underestimations amounted to 26–132 µmol/L at a TcB level of 250 µmol/L.

Conclusion
This in vitro study provides insight into the effect of skin color on TcB measurements: the TcB is underestimated as skin pigmentation increases and this effect becomes more pronounced at higher bilirubin levels. Our results highlight the need for improved TcB meter design and cautious interpretation of TcB readings on newborns with dark skin.

Impact

Key message: Skin color influences transcutaneous bilirubin measurements: the darker the skin, the larger the underestimation.

What this study adds to existing literature: Existing literature is inconclusive regarding the influence of skin color on transcutaneous bilirubin measurements. This study systematically evaluates and clarifies the influence of skin color on transcutaneous bilirubin measurements in a controlled, in vitro setting.

Impact: This study aids to better interpret the measured TcB level in patients with varying skin colors, and is particularly important when using TcB meters on patients with dark skin colors.
Elucidation of the role of metals in the adsorption and photodegradation of herbicides by metal-organic frameworks
Authors: Chiu Nan Chieh , Lessard Jacob M. , Musa Emmanuel Nyela , Lancaster Logan S. , Wheeler Clara , Krueger Taylor D. , Chen Cheng , Gallagher Trenton C. , Nord Makenzie T. , Huang Hongliang , Cheong Paul Ha-Yeon , Fang Chong , Stylianou Kyriakos C. 
Published: February 2024

AbstractHere, four MOFs, namely Sc-TBAPy, Al-TBAPy, Y-TBAPy, and Fe-TBAPy (TBAPy: 1,3,6,8-tetrakis(p-benzoic acid)pyrene), were characterized and evaluated for their ability to remediate glyphosate (GP) from water. Among these materials, Sc-TBAPy demonstrates superior performance in both the adsorption and degradation of GP. Upon light irradiation for 5 min, Sc-TBAPy completely degrades 100% of GP in a 1.5 mM aqueous solution. Femtosecond transient absorption spectroscopy reveals that Sc-TBAPy exhibits enhanced charge transfer character compared to the other MOFs, as well as suppressed formation of emissive excimers that could impede photocatalysis. This finding was further supported by hydrogen evolution half-reaction (HER) experiments, which demonstrated Sc-TBAPy’s superior catalytic activity for water splitting. In addition to its faster adsorption and more efficient photodegradation of GP, Sc-TBAPy also followed a selective pathway towards the oxidation of GP, avoiding the formation of toxic aminomethylphosphonic acid observed with the other M3+-TBAPy MOFs. To investigate the selectivity observed with Sc-TBAPy, electron spin resonance, depleted oxygen conditions, and solvent exchange with D2O were employed to elucidate the role of different reactive oxygen species on GP photodegradation. The findings indicate that singlet oxygen (1O2) plays a critical role in the selective photodegradation pathway achieved by Sc-TBAPy.
Mechanisms of extracellular electron transfer in anaerobic methanotrophic archaea
Authors: Ouboter Heleen T. , Mesman Rob , Sleutels Tom , Postma Jelle , Wissink Martijn , Jetten Mike S. M. , Ter Heijne Annemiek , Berben Tom , Welte Cornelia U. 
Published: February 2024

AbstractAnaerobic methanotrophic (ANME) archaea are environmentally important, uncultivated microorganisms that oxidize the potent greenhouse gas methane. During methane oxidation, ANME archaea engage in extracellular electron transfer (EET) with other microbes, metal oxides, and electrodes through unclear mechanisms. Here, we cultivate ANME-2d archaea (‘Ca. Methanoperedens’) in bioelectrochemical systems and observe strong methane-dependent current (91–93% of total current) associated with high enrichment of ‘Ca. Methanoperedens’ on the anode (up to 82% of the community), as determined by metagenomics and transmission electron microscopy. Electrochemical and metatranscriptomic analyses suggest that the EET mechanism is similar at various electrode potentials, with the possible involvement of an uncharacterized short-range electron transport protein complex and OmcZ nanowires.
Regulation of long-range BMP gradients and embryonic polarity by propagation of local calcium-firing activity
Authors: Lee Hyung Chul , Oliveira Nidia M. M. , Hastings Cato , Baillie-Benson Peter , Moverley Adam A. , Lu Hui-Chun , Zheng Yi , Wilby Elise L. , Weil Timothy T. , Page Karen M. , Fu Jianping , Moris Naomi , Stern Claudio D. 
Published: February 2024

AbstractMany amniote vertebrate species including humans can form identical twins from a single embryo, but this only occurs rarely. It has been suggested that the primitive-streak-forming embryonic region emits signals that inhibit streak formation elsewhere but the signals involved, how they are transmitted and how they act has not been elucidated. Here we show that short tracks of calcium firing activity propagate through extraembryonic tissue via gap junctions and prevent ectopic primitive streak formation in chick embryos. Cross-regulation of calcium activity and an inhibitor of primitive streak formation (Bone Morphogenetic Protein, BMP) via NF-κB and NFAT establishes a long-range BMP gradient spanning the embryo. This mechanism explains how embryos of widely different sizes can maintain positional information that determines embryo polarity. We provide evidence for similar mechanisms in two different human embryo models and in Drosophila, suggesting an ancient evolutionary origin.
A consistent map in the medial entorhinal cortex supports spatial memory
Authors: Malone Taylor J. , Tien Nai-Wen , Ma Yan , Cui Lian , Lyu Shangru , Wang Garret , Nguyen Duc , Zhang Kai , Myroshnychenko Maxym V. , Tyan Jean , Gordon Joshua A. , Kupferschmidt David A. , Gu Yi 
Published: February 2024

AbstractThe medial entorhinal cortex (MEC) is hypothesized to function as a cognitive map for memory-guided navigation. How this map develops during learning and influences memory remains unclear. By imaging MEC calcium dynamics while mice successfully learned a novel virtual environment over ten days, we discovered that the dynamics gradually became more spatially consistent and then stabilized. Additionally, grid cells in the MEC not only exhibited improved spatial tuning consistency, but also maintained stable phase relationships, suggesting a network mechanism involving synaptic plasticity and rigid recurrent connectivity to shape grid cell activity during learning. Increased c-Fos expression in the MEC in novel environments further supports the induction of synaptic plasticity. Unsuccessful learning lacked these activity features, indicating that a consistent map is specific for effective spatial memory. Finally, optogenetically disrupting spatial consistency of the map impaired memory-guided navigation in a well-learned environment. Thus, we demonstrate that the establishment of a spatially consistent MEC map across learning both correlates with, and is necessary for, successful spatial memory.
Oxygen-tolerant CO2 electroreduction over covalent organic frameworks via photoswitching control oxygen passivation strategy
Authors: Zhu Hong-Jing , Si Duan-Hui , Guo Hui , Chen Ziao , Cao Rong , Huang Yuan-Biao 
Published: February 2024

AbstractThe direct use of flue gas for the electrochemical CO2 reduction reaction is desirable but severely limited by the thermodynamically favorable oxygen reduction reaction. Herein, a photonicswitching unit 1,2-Bis(5’-formyl-2’-methylthien-3’-yl)cyclopentene (DAE) is integrated into a cobalt porphyrin-based covalent organic framework for highly efficient CO2 electrocatalysis under aerobic environment. The DAE moiety in the material can reversibly modulate the O2 activation capacity and electronic conductivity by the framework ring-closing/opening reactions under UV/Vis irradiation. The DAE-based covalent organic framework with ring-closing type shows a high CO Faradaic efficiency of 90.5% with CO partial current density of −20.1 mA cm−2 at −1.0 V vs. reversible hydrogen electrode by co-feeding CO2 and 5% O2. This work presents an oxygen passivation strategy to realize efficient CO2 electroreduction performance by co-feeding of CO2 and O2, which would inspire to design electrocatalysts for the practical CO2 source such as flue gas from power plants or air.
Tuning ferroelectric phase transition temperature by enantiomer fraction
Authors: Fan Chang-Chun , Liu Cheng-Dong , Liang Bei-Dou , Wang Wei , Jin Ming-Liang , Chai Chao-Yang , Jing Chang-Qing , Ju Tong-Yu , Han Xiang-Bin , Zhang Wen 
Published: February 2024

AbstractTuning phase transition temperature is one of the central issues in phase transition materials. Herein, we report a case study of using enantiomer fraction engineering as a promising strategy to tune the Curie temperature (TC) and related properties of ferroelectrics. A series of metal-halide perovskite ferroelectrics (S−3AMP)x(R−3AMP)1−xPbBr4 was synthesized where 3AMP is the 3-(aminomethyl)piperidine divalent cation and enantiomer fraction x varies between 0 and 1 (0 and 1 = enantiomers; 0.5 = racemate). With the change of the enantiomer fraction, the TC, second-harmonic generation intensity, degree of circular polarization of photoluminescence, and photoluminescence intensity of the materials have been tuned. Particularly, when x = 0.70 − 1, a continuously linear tuning of the TC is achieved, showing a tunable temperature range of about 73 K. This strategy provides an effective means and insights for regulating the phase transition temperature and chiroptical properties of functional materials.
Assessing the efficacy of target adaptive sampling long-read sequencing through hereditary cancer patient genomes
Authors: Nakamura Wataru , Hirata Makoto , Oda Satoyo , Chiba Kenichi , Okada Ai , Mateos Raúl Nicolás , Sugawa Masahiro , Iida Naoko , Ushiama Mineko , Tanabe Noriko , Sakamoto Hiromi , Sekine Shigeki , Hirasawa Akira , Kawai Yosuke , Tokunaga Katsushi ,   NCBN Controls WGS Consortium, Ishibashi-Ueda Hatsue , Tomita Tsutomu , Noguchi Michio , Takahashi Ayako , Goto Yu-ichi , Yoshida Sumiko , Hattori Kotaro , Matsumura Ryo , Iida Aritoshi , Maruoka Yutaka , Gatanaga Hiroyuki , Sugiyama Masaya , Suzuki Satoshi , Miyo Kengo , Matsubara Yoichi , Umezawa Akihiro , Hata Kenichiro , Kaname Tadashi , Ozaki Kouichi , Tokuda Haruhiko , Watanabe Hiroshi , Niida Shumpei , Noiri Eisei , Kitajima Koji , Omae Yosuke , Miyahara Reiko , Shimanuki Hideyuki , Tsujimoto Shin-ichi , Shiba Norio , Ito Shuichi , Yoshida Teruhiko , Shiraishi Yuichi 
Published: February 2024

AbstractInnovations in sequencing technology have led to the discovery of novel mutations that cause inherited diseases. However, many patients with suspected genetic diseases remain undiagnosed. Long-read sequencing technologies are expected to significantly improve the diagnostic rate by overcoming the limitations of short-read sequencing. In addition, Oxford Nanopore Technologies (ONT) offers adaptive sampling and computationally driven target enrichment technology. This enables more affordable intensive analysis of target gene regions compared to standard non-selective long-read sequencing. In this study, we developed an efficient computational workflow for target adaptive sampling long-read sequencing (TAS-LRS) and evaluated it through application to 33 genomes collected from suspected hereditary cancer patients. Our workflow can identify single nucleotide variants with nearly the same accuracy as the short-read platform and elucidate complex forms of structural variations. We also newly identified several SINE-R/VNTR/Alu (SVA) elements affecting the APC gene in two patients with familial adenomatous polyposis, as well as their sites of origin. In addition, we demonstrated that off-target reads from adaptive sampling, which is typically discarded, can be effectively used to accurately genotype common single-nucleotide polymorphisms (SNPs) across the entire genome, enabling the calculation of a polygenic risk score. Furthermore, we identified allele-specific MLH1 promoter hypermethylation in a Lynch syndrome patient. In summary, our workflow with TAS-LRS can simultaneously capture monogenic risk variants including complex structural variations, polygenic background as well as epigenetic alterations, and will be an efficient platform for genetic disease research and diagnosis.
High-intensity acute exercise impacts motor learning in healthy older adults
Authors: Taylor Eleanor M. , Cadwallader Claire J. , Curtin Dylan , Chong Trevor T.-J. , Hendrikse Joshua J. , Coxon James P. 
Published: February 2024

AbstractHealthy aging is associated with changes in motor sequence learning, with some studies indicating decline in motor skill learning in older age. Acute cardiorespiratory exercise has emerged as a potential intervention to improve motor learning, however research in healthy older adults is limited. The current study investigated the impact of high-intensity interval exercise (HIIT) on a subsequent sequential motor learning task. Twenty-four older adults (aged 55–75 years) completed either 20-minutes of cycling, or an equivalent period of active rest before practicing a sequential force grip task. Skill learning was assessed during acquisition and at a 6-hour retention test. In contrast to expectation, exercise was associated with reduced accuracy during skill acquisition compared to rest, particularly for the oldest participants. However, improvements in motor skill were retained in the exercise condition, while a reduction in skill was observed following rest. Our findings indicate that high-intensity exercise conducted immediately prior to learning a novel motor skill may have a negative impact on motor performance during learning in older adults. We also demonstrated that exercise may facilitate early offline consolidation of a motor skill within this population, which has implications for motor rehabilitation.