bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceived treatment urgency of common mental disorders in the German population
Authors: Koens Sarah , Klein Jens , Scherer Martin , Strauß Annette , Härter Martin , Schäfer Ingo , Lüdecke Daniel , von dem Knesebeck Olaf 
Published: December 2023

AbstractPerceived treatment urgency of mental disorders are important as they determine utilization of health care. The aim was to analyze variations in perceived treatment urgency in cases of psychosis (adolescents), alcoholism (adults), and depression (older adults) with two levels of severity each by characteristics of the case and the respondents. A telephone survey (N = 1200) with vignettes describing cases of psychosis, alcoholism, and depression was conducted in Hamburg, Germany. Vignettes varied by symptom severity and sex. Perceived treatment urgency was assessed by three items. A sum scale was calculated. Linear regression models were computed to analyze differences in perceived urgency by characteristics of the case (severity, sex) and the respondents (sex, age, education, migration background, illness recognition, personal affliction). Perceived treatment urgency was significantly higher in severe cases and varied by education. Additionally, regarding psychosis, estimated urgency varied significantly by correct illness recognition. With regard to depression, perceived urgency differed significantly by age and correct illness recognition. Interaction effects between case severity and sociodemographic characteristics of the respondents, personal affliction, and correct recognition of the disorder were found. The identified differences should be considered in the development of interventions on mental health literacy with regard to adequate urgency assessment.
Le « Grand remplacement » pendant la pandémie
Authors: Lavialle-Prélois Julie 
Published: December 2023

La théorie du « Grand remplacement », qui s’inscrit dans une logique sémantique complotiste mêlant xénophobie et populisme, apparaît entrer en résonnance avec la remise en cause de l’Autre dans toutes ses figures en temps de pandémie. Cet article propose ainsi d’interroger la manière dont la diffusion de la théorie a pu être impactée par les reconfigurations que la pandémie de la Covid-19, construite collectivement comme une crise sanitaire, a induites.
Je propose de mener cette analyse à partir de l’étude comparative des récits complotistes élaborés autour de la crise sanitaire et des récits élaborés autour du « Grand remplacement », entendu comme un mythe politique en ce qu’il prend en charge l’émotionnel de la réalité perçue en l’inscrivant dans la doxa sacralisée de l’ethnonationalisme.
Je m’intéresserai aux variables qui semblent sous-tendre ces agirs politiques (élaborations de récits complotistes) dans les contextes anxiogènes où se recouvrent crise sanitaire et crise politique. Cette perspective nous amènera à considérer que la diffusion de la théorie xénophobe en temps de pandémie n’apparaît pas tant dépendante des stratégies argumentaires et rhétoriques spécifiques déployées par les diffuseurs que d’un besoin de fixation des angoisses projeté à l’échelle collective par l’élaboration de récits partagés.
Mister Him, passeur d’une langue que notre bouche ignore
Authors: de Ferrières Cécile 
Published: December 2023

Faut-il dans un questionnement analytique prendre appui sur un « savoir théorique » ou faut-il opter pour un cheminement orienté depuis le Réel où la pensée théorique se révèle être un tout autre recours ? Telle est la question que la longue fréquentation de Mister Him, au cours de repas dits thérapeutiques, m’aura menée à soutenir ici. À défaut d’échanges de paroles, je suis partie de ses silences, de ses gestes, de ses regards, pour me laisser traverser par cette forme d’existence anonyme et singulière « réfractaire à toute domestication symbolique ». C’est l’invite à un saut à partir de l’inconnu en soi.
Ecocide as a New Core Crime in the Rome Statute? An Ultima Ratio Lens on Legal Policy in International Criminal Law
Authors: Zink Sarah 
Published: December 2023

Abstract
The protection of the environment is currently of the uppermost importance and all legal fields have to contribute to this goal. This includes criminal law, both on a national and an international level. The debate in international criminal law focusses on a proposal to introduce a new core crime of “ecocide” to the Rome Statute. Much has been contributed to this debate, and often the ultima ratio approach has been mentioned in this context. However, the contents of this principle remain vague. In my article, I assess the ultima ratio principle for international criminal law and apply it to the discussion about the introduction of a new core crime of ecocide to the Rome Statute. My assessment reveals that under the current circumstances, this cannot be considered a good fit. Rather, alternatives exist that are to be expected to serve the urgent interest of protecting the natural environment better.
Characteristics and outcomes of children, adolescents and young adults with relapsed/refractory non-hodgkin lymphoma undergoing autologous stem cell transplant
Authors: Pasvolsky Oren , Bassett Roland L. , Ghanem Sassine , Cuglievan Branko , Tewari Priti , Hosing Chitra , Srour Samer , Ramdial Jeremy , Mahadeo Kris M. , Khazal Sajad , Petropoulos Demetrios , Popat Uday , Qazilbash Muzaffar , Kebriaei Partow , Champlin Richard , Shpall Elizabeth J. , Nieto Yago 
Published: December 2023

Abstract
Background
There is paucity of data regarding outcomes of children, adolescents and young adults (CAYA) patients with non-Hodgkin lymphoma (NHL) undergoing autologous stem cell transplantation (ASCT).

Methods
Patients aged 0–39 years undergoing first ASCT for NHL at MD Anderson Cancer Center between 2000 and 2020 were analyzed.

Results
Two hundred twenty-one patients were included in the analysis, 129 (58%) were male and the median age was 32 (range 6–39) years. The most common histological subtypes were diffuse large B cell lymphoma (DLBCL) (44%), T-NHL (19%) and primary mediastinal B-Cell lymphoma (PMBCL) (19%). Younger patients (age ≤ 25) had lower incidence of DLBCL and higher incidence of PMBCL and T-NHL compared to older patients (age > 25) (P = 0.02). None of the younger patients had double hit (DH)/double expressor (DE) DLBCL, compared to 14 patients in the older age group (18%, P = 0.07). Considering the three main aggressive NHL subtypes (DLBCL, PMBCL and T-NHL), younger patients had numerically better 15-year post-transplant progression free survival (PFS) (67% vs. 54%) and overall survival (OS) (71% vs. 62%) compared to older patients, yet these differences did not reach statistical significance (P = 0.19 and P = 0.24, respectively). In multivariate analysis, not achieving a CR prior to ASCT was independently predictive of worse PFS [partial remission (PR) (HR, 3.9); stable disease (SD) (HR, 18.0), P = 0.03] and of worse OS [PR (HR, 4.2), SD (HR, 6.5) and progressive disease (HR, 4.7), P < 0.0001]. DH/DE status was an independent adverse predictor of PFS in multivariate analysis (HR 5.8, p = 0.03).
Ten patients (4.5%) (all aged > 25 years) developed second primary malignancies (SPM), at a median of 34.4 (range, 1.0–196.6) months after ASCT, and SPM was the cause of death in five (50%) of them.

Conclusions
CAYA NHL patients aged ≤ 25 years who received ASCT presented a distinct NHL histology as compared to older CAYA patients, and none in this younger age group had DH/DE DLBCL. We observed a trend towards improved PFS and OS in younger patients. Disease status at ASCT was predictive of both PFS and OS. DH/DE status was an adverse predictor of PFS.
Comparison of energy expenditure measurements by a new basic respiratory room vs. classical ventilated hood
Authors: Van Soom Timia , Tjalma Wiebren , Van Daele Ulrike , Gebruers Nick , van Breda Eric 
Published: December 2023

Abstract
Background
Nutritional support is often based on predicted resting energy expenditure (REE). In patients, predictions seem invalid. Indirect calorimetry is the gold standard for measuring EE. For assessments over longer periods (up to days), room calorimeters are used. Their design makes their use cumbersome, and warrants improvements to increase utility. Current study aims to compare data on momentary EE, obtained by a basic respiration room vs. classical ventilated hood. The objective is to compare results of the basic room and to determine its 1)reliability for measuring EE and 2)sensitivity for minute changes in activity.

Methods
Two protocols (P1; P2)(n = 62; 25 men/37 women) were applied. When measured by hood, participants in both protocols were in complete rest (supine position). When assessed by room, participants in P1 were instructed to stay half-seated while performing light desk work; in P2 participants were in complete rest mimicking hood conditions. The Omnical calorimeter operated both modalities. Following data were collected/calculated: Oxygen uptake ($$\dot{\mathrm{V}}$$

V
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O2(ml/min)), carbon dioxide production ($$\dot{\mathrm{V}}$$

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CO2ml/min), 24h_EE (kcal/min), and respiratory exchange ratio (RER). Statistical analyses were done between modalities and between protocols. The agreement between 24h_EE, $$\dot{\mathrm{V}}$$

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O2 and $$\dot{\mathrm{V}}$$

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CO2 obtained by both modalities was investigated by linear regression. Reliability analysis on 24h_EE determined ICC.

Results
No significant differences were found for 24h_EE and $$\dot{\mathrm{V}}$$

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O2. $$\dot{\mathrm{V}}$$

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CO2 significantly differed in P1 + P2, and P2 (hood > room). RER was significantly different (hood > room) for P1 + P2 and both protocols individually. Reliability of 24h_EE between modalities was high. Modality-specific results were not different between protocols.

Discussion/conclusion
The room is valid for assessing momentary EE. Minute changes in activity lead to a non-significant increase in EE and significant increase in RER. The significant difference in $$\dot{\mathrm{V}}$$

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CO2 for hood might be related to perceived comfort. More research is necessary on determinants of RER, type (intensity) of activity, and restlessness. The design of the room facilitates metabolic measurements in research, with promising results for future clinical use.
Wealth-based inequity in full child vaccination coverage: An experience from Mali, Bangladesh, and South Africa. A multilevel poison regression
Authors: Birhanu Frehiwot , Yitbarek Kiddus 
Published: December 2023

Objectives
Every child around the globe should get routine childhood vaccination, which is mostly affected by the country’s economic capacity besides the socioeconomic differences. However, how well countries with different economic capacities address equitable child vaccination remains unanswered.

Methods
Cross-sectional data from the latest Demographic and Health Survey (DHS) database of Mali, Bangladesh, and South Africa was used for this study. The dependent variable was full child vaccination, and wealth-based inequality was assessed using rate-ratio, concentration curve, and concentration index. A multilevel Poisson regression analysis was used to determine the predictors of inequalities. A risk ratio (RR) with a p-value of 0.05 was used to declare statistical significance. All analysis was weighted.

Results
Full child vaccination status was 30.15%, 62.18%, and 46.94% in Mali, Bangladesh, and South Africa respectively. Even if the disparity is higher in Mali, the full vaccination favors the better-off family both in Mali, and Bangladesh respectively [CInd: 0.05, 95% CI: 0.01, 0.09], [CInd: 0.02, 95% CI: 0.001, 0.03], wealth status did not have an effect in South Africa. The multilevel poison regression indicated maternal age, occupation, wealth of household, and frequency of watching television to positively affect full vaccination, whereas the number of children in the house negatively affected full vaccination.

Conclusion
Wealth-based inequality in child vaccination was higher in Mali followed by Bangladesh. There was no observable significant equity gap in South Africa. Wealth status, maternal occupation, maternal age, frequency of watching television, and number of children were predictors of full child vaccination.
Comparing the effectiveness of mother-focused interventions to that of mother-child focused interventions in improving maternal postpartum depression outcomes: A systematic review
Authors: Kumar Divya , Hameed Waqas , Avan Bilal Iqbal 
Published: December 2023

Background
Most empirically researched interventions for postpartum depression (PPD) tend to target mothers’ depression alone. Harmful effects of PPD on physical and mental health of both mother and child has led researchers to investigate the impact of interventions on PPD and child outcomes together. So far, the evidence is limited regarding how these interventions compare with those focusing only on mothers’ depression. This review compares the effectiveness of PPD-improving interventions focusing only on mothers with those focusing on mother and child together.

Methods
Nine electronic databases were searched. Thirty-seven studies evaluating mother-focused (n = 30) and mother-child focused interventions (n = 7) were included. Under each category, three theoretical approaches—psychological, psychosocial and mixed—were compared using standardized qualitative procedures. The review’s primary outcome was maternal PPD.

Results
A higher proportion of mother-focussed interventions [20/30 (66.7%)] brought significant reduction in PPD outcomes as compared to a lower proportion of mother-child focused interventions [4/7 (57.14%)]. Mother-focused mixed approaches [3/3 (100%)] performed better in improving PPD than psychological [16/24 (67%)] or psychosocial approaches [1/3 (33.3%)] alone. Amongst mother-child focused interventions, psychosocial approaches performed well with two-thirds demonstrating positive effects on PPD.

Conclusion
The evidence strongly favors mother-focused interventions for improving PPD with mixed interventions being more effective. Psychosocial approaches performed better with PPD once child-related elements were added, and also seemed best for child outcomes. Psychological approaches were most practiced and effective for PPD, irrespective of the intervention’s focus. Further trials are needed to unpack intervention components that improve PPD and increase uptake, especially in lower-and middle-income countries.
Talaios Koop. (2023): Sindicalismo y economía social para la transformación Fundación. Sindicalismo Transformador, Economía Social y Transformadora y estrategia económica soberanista para Hegoalde. Bilbao: Manu Robles-Arangiz Institutua.
Authors: Herrera Cuesta Damián 
Published: December 2023

En este trabajo, el grupo Talaios Koop, nos presenta una propuesta bien cerrada, proporcionando elementos objetivos para construir una estrategia socioeconómica soberanista basada en una economía sustantiva y orientada hacia modelos productivos democráticos y soberanos impulsados, interesante novedad, por un sindicalismo transformador.
Advances in the pharmaceutical research of curcumin for oral administration
Authors: Li Cheng , Naeem Abid , Shen Jiangwen , Zha Weiwei , Zeng Qingyun , Zhang Peng , Li Lin , Liao Zhenggen , Chen Xulong 
Published: December 2023

Abstract
Curcumin is an isolated phytopolyphenol pigment found in the Curcuma longa, commonly known as turmeric, with various pharmacological properties. It has many effects, including anti-tumour, anti-inflammatory, anti-bacterial, anti-oxidation, and hypoglycemic properties. However, due to its oral bioavailability, the use of the drug in the clinical environment is limited. Moreover, curcumin’s low bioavailability is attributed to its insoluble nature, poor permeability, and inhibition of P-glycoprotein efflux and enzyme metabolism. Several new dosage forms of curcumin have been developed based on its physical properties to improve oral administration. However, the curcumin oral administration system still needs to be improved from the perspective of both research and clinical applications.
Significance of monitoring the levels of thyroid hormone antibodies and glucose and lipid metabolism antibodies in patients suffer from type 2 diabetes
Authors: Liu Xuefang , Qiu Youyan , Chen Dandan , Xiong Jingni , Xia Biwen , Chen Caiqin , Li Suyan 
Published: December 2023

Abstract
The association of thyroid hormone antibodies and glycolipid metabolism indicators with Type 2 diabetes mellitus (T2DM) was explored. As the disease worsens, the levels of thyroglobulin antibody (TGAb), thyroid peroxidase antibody (TPOAb), and thyroid-stimulating hormone (TSH) was increased, and the levels of total tri-iodothyronine (TT3) and total thyroxine (TT4) was decreased (P < 0.001). The severe, medium, and light group had higher level of high-density lipoprotein (HDL), lower level of total cholesterol (TC), low-density lipoprotein (LDL), glycosylated hemoglobin (HbA1c), triacylglycerol (TAG), and fasting blood sugar (FBG) than the control group (P ＜ 0.05). The level of HDL was lower in the severe group than the light group and the medium group, but the levels of TC, LDL, HbA1c, TAG, and FBG were increased with the progress of T2DM (P ＜ 0.001). The levels of TGAb, TPOAb, and TSH in patients with T2DM were positively correlated with the levels of TC, LDL, HbA1c, TAG, and FBG (P < 0.05), and were negatively correlated with HDL levels (P < 0.05). The life quality score was lower in the severe group than the light and the medium group (P < 0.001). Among the above indicators, the predictive value of TT3, TT4, and HbA1c in T2DM was better. Clinically, detecting the levels of thyroid hormone antibodies and glycolipid metabolism indicators had a certain predictive value for the severity of T2DM.

Main findings: The results of this study found that the thyroid hormone antibody and glycolipid metabolism levels in T2DM patients were abnormal, and had different degrees of impact on the quality of life of patients. Thus, monitoring these indicators had certain predictive value for the severity of the disease, and also had a certain degree of suggestive effect on the evaluation of diabetic vascular complications. Clinically, attention should be paid to the screening of thyroid disease in diabetic patients, and the assessment and prognosis of thyroid function on diabetes, the control of diabetes, and the prevention and treatment of complications have important clinical significance.
Introduction to Lexical constraints in grammar: Minority verb classes and restricted alternations
Authors: Walker Katherine , Faghiri Pegah 
Published: December 2023

Abstract
This is an introduction to the Special Issue Lexical constraints in grammar: Minority verb classes and restricted alternations. In many languages, grammatical relations are subject to lexical constraints. These constraints can be manifested in different morphosyntactic domains, for instance, through deviation from canonical case frames or different argument indexation patterns. Other constructions that have been studied through this lens are voice and valency constructions and some clause-combining constructions. The types of oppositions established by lexical constraints vary: some absolute restrictions entail the obligatory presence or absence of a grammatical marker, while others entail the ability of a lexical item to alternate. In the latter instance, differences in the statistical preferences for one construction over another may be observed. In some cases, verb classes can be easily identified based on a common semantic feature; however, various other factors can also lead to the formation of minority verb classes and restrictions on alternations. This article introduces a collection of four articles investigating lexical constraints in a variety of morphosyntactic domains, adopting different perspectives and methodologies. It sets out a framework for considering different opposition types formed by the differing behaviour of different verb classes and outlines a number of different factors that motivate the formation of verb classes. This introductory article shows that lexical constraints provide fertile ground for typologists adopting a token-based approach seeking to compare languages at ever-greater levels of specification.
Extracting solitary solutions of the nonlinear Kaup–Kupershmidt (KK) equation by analytical method
Authors: Alharthi Mohammed Shaaf 
Published: December 2023

Abstract
Finding analytical solutions for nonlinear partial differential equations is physically meaningful. The Kaup-Kupershmidt (KK) equation is studied in this article. The KK equation is of fifth order, such that several solitary solutions are obtained. In this article, however, the modified auxiliary function approach is applied to this model to find solitary solutions. These solutions are written in terms of Jacobi functions. Therefore, the obtained solutions can be implemented graphically to show different patterns for appropriate parameters.
PREVALENCE RATE OF ESBL AMONG ENTEROBACTERIACEAE ISOLATED FROM UTI PATIENTS IN SULAIMANI PROVINCE
Authors: Abdalrahman Azhi , Anwar Khanda 
Published: December 2023

Background Extended-Spectrum β-Lactamase are enzymes that provide resistance against third-and fourth generation Cephalosporins and Monobactams, and they are distributed among the Enterobacteriaceae family.
Objectives To describe the prevalence of Extended-Spectrum β-Lactamase among Enterobacteriaceae causing urinary tract infections in Sulaimani province.
Patients and MethodsOne hundred bacterial isolates of Enterobacteriaceae from patients with urinary tract infections attending Smart Hospital (inpatients and outpatients). Urine samples were inoculated onto different culture media. Colony morphology, gram staining, and BD Phoenix™ system were used for bacterial identification. Antibiotic profile and Extended-Spectrum β-Lactamase were observed phenotypically by antibiotic profile results, double disk synergy test, and confirmed by combined disk test methods and BD Phoenix™ system.
ResultsOut of one hundred isolates of Enterobacteriaceae, Escherichia coli was the commonest isolate (89), followed by Klebsiella pneumoniae (10) and one isolate of Proteus mirabilis. According to the antibiotic profile, the most effective antibiotic among all three isolates was Imipenem and Nitrofurantoin, while the most resistant antibiotic was Nalidixic acid and third generation Cephalosporin. The prevalence rate of Extended-Spectrum β-Lactamase -producing Enterobacteriaceae was 69% by the screening tests and 48% by the confirmatory tests.
ConclusionIn this study, Extended-Spectrum β-Lactamase prevalence was shown to be at an alarming rate that must be considered. The high priority of public health justifies further investigation to properly establish annual surveillance systems that can aid in selecting an appropriate antibiotic upon ESBL detection.