bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural and metamorphic evolution of a subducted passive margin: insights from the Briançonnais nappes of the Western Alps (Ubaye–Maira valleys, France–Italy)
Authors: Dana Davide , Iaccarino Salvatore , Schmid Stefan M. , Petroccia Alessandro , Michard André 
Published: November 2023

AbstractThis contribution analyses the structural architecture and tectono-metamorphic evolution of Briançonnais units in the southern French-Italian Western Alps. The studied area extends from a virtually non-metamorphic area adjacent to the Helvetic-Dauphinois External Domain in the west to the Monviso-Queyras ocean-derived units in the east, where metamorphism increases up to eclogite-facies. Mapping at the scale 1:10.000 of a mountainous part of the Ubaye-Maira transect was performed, which portrays in detail the Briançonnais units over ~ 100 km2. The lithologies include meta-andesite, meta-siliciclastics, marbles, turbiditic calcschists and flysch whose age spans from Late Carboniferous to Eocene. Metamorphism is low-grade greenschist-facies in the west but reaches the blueschist-facies to the east. Structures related to four phases of deformation are identified. The first two generations of structures (D1–D2), related to the original top-to-the-west nappe stacking, are associated with conditions close to the peak of Alpine metamorphism. Previous tectonic surfaces are transposed by the dominant deformation structures (D3), developed under retrograde/decompression conditions. This D3 corresponds to a backfolding and back-thrusting event with a top-to-the-E transport. A fourth phase (D4) developed during late low-grade metamorphic conditions and deforms the previous surfaces by locally developing a crenulation cleavage, followed by brittle tectonics. An updated metamorphic map is presented, backed on published estimates and new thermometric data obtained by Raman Spectroscopy of Carbonaceous Material (RSCM). The TRSCM values range from ~ 295 °C to > 350 °C, moving from the most external Briançonnais unit to the internal Queyras “Schistes Lustrés” units. Suspected Upper Cretaceous palaeofaults have been documented, allowing us to group the classic Aiguille de Mary and Ceillac (sub-) units into a single tectonic unit, here referred to as Maurin unit. The palaeogeographical reconstruction of the evolution of the studied transect highlights the importance of the Marinet and Maurin axial units in the feeding of the Late Cretaceous-Eocene breccias deposited on the more internal Acceglio-type units.
Effect of educational intervention on risk factors of cardiovascular diseases among school teachers: a quasi-experimental study in a suburb of Kolkata, West Bengal, India
Authors: Karmakar Anubrata , Bhattacharyya Aritra , Biswas Bijit , Dasgupta Aparajita , Bandyopadhyay Lina , Paul Bobby 
Published: November 2023

Abstract
Objective
This prospective study aimed to evaluate the effects of a health education intervention on cardiovascular disease (CVD) risk factors among school teachers.

Methods
The study, conducted from August 2016 to May 2017, involved teachers from four schools in Baruipur, West Bengal, India. It was a multicentric, quasi-experimental study with an intervention group receiving tailored health education promoting lifestyle modifications, while the control group received no intervention. Baseline and endline assessments included behavioural and biological characteristics related to cardiovascular health and risk assessment. Data were analysed using JAMOVI.

Results
The intervention group showed significant improvements in physical activity levels [Cohen’s d (Cd): 0.43, p = 0.006] and the consumption of fruits and vegetables (Cd: 1.00, p = < 0.001). Notably, there was a considerable reduction in the consumption of salt (Cd: -0.93, p = 0.039), oil (Cd: -0.98, p = < 0.001), fast food (Cd: -0.99, p = < 0.001), junk food (Cd: -0.99, p = < 0.001), and red meat (Cd: -1.00, p = < 0.001) among participants. However, there were no significant improvements in biological characteristics within the intervention group. In contrast, the control group exhibited no significant changes in behavioural and biological characteristics compared to baseline. The intervention group showed a minor non-significant reduction (3.0%) in their 10-year cardiovascular risk compared to baseline (Cd: -1.00, p = 0.50), while the control group had a negligible non-significant increase (0.7%) in their cardiovascular risk (Cd: 1.00, p = 1.00).

Conclusion
Health education intervention positively influenced behavioural characteristics, such as physical activity and dietary habits, among school teachers. However, no significant improvements were observed in biological characteristics or cardiovascular risk factors.
1470 nm laser is better for prostate hyperplasia treatment with different volume size via transurethral enucleation
Authors: Fayou Zhou , Jiude Zheng , Shuxian Zhang , Yajun Shen , Wei Xu , Jia Yu , Fan Su , Yueling Xiong , Renrui Han , Xiaolei Tang 
Published: November 2023

Abstract
Introduction
The large amount of intraoperative bleeding and the high incidence of postoperative hematuria are still common factors affecting the prostate surgery treatment effect. Our research aimed to observe the effect of prostatic enucleation using 1,470 nm semiconductor laser on the amount of bleeding in patients with different sizes of prostate hyperplasia.

Methods
According to the size of the prostate, forty eligible patients with benign prostatic hyperplasia (BPH) were enrolled and divided into low and high volume group in this study. Hemoglobin decline, urinating condition, complications and erectile function were collected and compared before and after surgery.

Results
Our data showed that hemoglobin decline was (10.0 ± 6.2) g/L and (12.1 ± 7.8) g/L, respectively for two group after surgery (P = 0.363). Urination was significantly improved following surgery in both groups of patients (P < 0.05), and no permanent urinary incontinence and sexual dysfunction and so no serious complications occurred.

Conclusion
The above results suggested that prostatic enucleation using 1,470 nm semiconductor laser can be safe and effective for prostatic hyperplasia, and this surgery produced no significant effect on the amount of bleeding in whatever size of the prostate.
Vector-borne parasites in dogs from Ukraine translocated to Poland following Russian invasion in 2022
Authors: Bajer Anna , Alsarraf Mustafa , Topolnytska Mariia , Tołkacz Katarzyna , Dwużnik-Szarek Dorota , Rodo Anna 
Published: November 2023

Abstract
Introduction
Since 24 February 2022, the day the Russian aggression against Ukraine began, millions of refugees and thousands of pets crossed the Polish-Ukrainian border. Additionally, an unknown number of shelter and stray dogs and cats were rescued and translocated to Poland by private persons and non-profit organizations. The aim of the present study was to examine rescued dogs and cats for presence of canine vector-borne parasites to determine the role of armed conflict in spreading these parasites.

Methods
In July 2022 blood samples were collected from two animal shelters in central Poland hosting dogs and cats rescued from Ukraine. Animals were imported from various regions of Ukraine, including eastern and southeastern Ukraine (military conflict area). Fifty-three dogs (51 from two shelters and two owned ones) and one shelter cat were examined by molecular methods (PCR and sequencing) for the presence of Babesia/Theileria spp., Dirofilaria spp. and Hepatozoon spp. DNA.

Results
We detected Dirofilaria immitis, a parasite species non-endemic in Poland, in two dogs translocated from Ukraine (2/53 = 3.8% [95% CI 0.5–13.0%]). One dog had a history of previous heartworm infection. High prevalence of Hepatozoon canis (51% [95% CI 36.8–64.9%]) was noted among translocated dogs. Prevalence of Dirofilaria repens in Ukrainian dogs (18.9% [95% CI 9.4–32.0%) was similar to prevalence in dogs from central Poland (12%). Co-infection of D. repens and D. immitis was found in two dogs and six dogs were co-infected by D. repens and H. canis. Hepatozoon canis infection was also identified in an imported cat.

Conclusion
We confirmed that this military conflict has facilitated the spread of canine vector-borne parasites, including zoonotic species.

Graphical Abstract
Study on the association between adverse drug reactions to opioids and gene polymorphisms: a case-case–control study
Authors: Yang Jing , Sun Ying-zi , Li Qun-fang , Fu Zheng , Guan Yu-yao , Song Chao , Zheng Lei 
Published: November 2023

Abstract
Objective
Adverse drug reactions (ADRs) caused by opioid drugs show individual differences. Our objective was to explore the association between gene polymorphism and ADRs induced by opioid drugs.

Methods
Evidence-based medical data analysis was conducted for genes related to ADRs induced by opioid drugs to select target genes. Sixty patients with cancer pain who had ADRs after taking opioid drugs (morphine, codeine, oxycodone) and 60 patients without ADRs after taking opioid drugs were used as the experimental group and control group, respectively. Then, we used polymerase chain reaction (PCR) or in situ hybridization to detect target genes. By combining with clinical data such as age, sex, dosage and duration of medication, the effect of gene polymorphism on the ADR of patients after taking opioid drugs was statistically analysed.

Results
Based on a database search and evidence-based medical data, we identified CYP2D6*10, CYP3A5*3, ABCB1, and OPRM1 as target genes for detection. The results of statistical analysis showed no significant difference in genotype distribution between the experimental group and the control group (p > 0.05). However, if 32 patients with ADRs after taking oxycodone and 32 controls were selected for comparison, the SPSS22.0 and SNPStats genetic models showed that the ABCB1 (062rs1045642) CT and TT genotypes correlated with the occurrence of ADRs (p < 0.05): the total number of CT + TT genotypes in the experimental group was 29 (90.62%), with 11 (34.37%) CT + TT genotypes types in the control group.

Conclusion
Polymorphism of ABCB1 (062rs1045642) is related to ADRs caused by oxycodone, and the incidence of ADRs is higher with the allele T. Polymorphism of ABCB1 is expected to become a clinical predictor of ADRs to oxycodone, and attention should be given to the occurrence of serious ADRs in patients with ABCB1 (062rs1045642) CT and TT genotypes.
The relationship between childhood emotional abuse and borderline personality disorder: the mediating role of difficulties in emotion regulation among Lebanese adults
Authors: Kanj Gaelle , Hallit Souheil , Obeid Sahar 
Published: November 2023

Abstract
Objective
The present study investigates the mediating effect of difficulties in emotion regulation in the association between childhood emotional abuse and Borderline Personality Disorder (BPD) among Lebanese adults.

Method
This cross-sectional study, involving 411 participants, was conducted between March and August 2022. Lebanese individuals from all governorates of the country were recruited using the Snowball Sampling technique. Three self-report scales were utilized to complete this research; the ‘Difficulties in Emotion Regulation Scale—Brief Version (DERS-16)’ which evaluates the difficulties in emotion regulation of individuals, the ‘Childhood Trauma Questionnaire—Short Form (CTQ-SF)’ which grants a subjective evaluation of the general childhood environment of the participants, as well as the ‘Borderline Personality Questionnaire (BPQ)’ which measures Borderline Personality Disorder traits, that demonstrate significant convergence with the disorder.

Results
The results indicate that DERS-16 played an indirect effect role between childhood emotional abuse scores and Borderline Personality Disorder. Higher emotional abuse scores were significantly associated with higher DERS-16 scores, which in turn was significantly associated with higher BPQ scores. Moreover, childhood emotional abuse was directly associated with higher BPQ scores.

Conclusion
This work suggests that, among the different forms of childhood abuse, emotional abuse may have a role in the development of Borderline Personality Disorder. Training on emotion regulation strategies would potentially benefit individuals in preventing BPD development and facilitating therapeutic processes.
Disability and Belonging in an Inclusive Christian Faith Community
Authors: Huggins Deborah W. , Copeland Susan R. 
Published: November 2023

Abstract
The voices of people with intellectual and developmental disabilities (IDD) are underrepresented in research examining their participation in faith communities. This qualitative case study examined the participation of people with ASD (autism spectrum disorder, a type of IDD) in one intentionally inclusive Christian faith community with a primary focus on the perceptions of faith community members with disabilities. This community was unique in its theological stance toward inclusion and in the steps the community had already taken to be inclusive. We conducted two types of interviews (in-depth individual and PhotoVoice) with people with severe and moderate disabilities who were active in the community to explore their perceptions of participation and belonging in the community. We supported interview data with field observations and a document review. We prioritized the voices of people with disabilities by using in-vivo coding strategies based on their words and used thematic analysis across data sources. Three primary themes emerged from this analysis including: Leadership, relationships, and traditions and routines. The implications of this study include suggestions to support authentic participation of people with IDD in faith community settings, implications for research with people with IDD in these settings.
Towards a community-driven definition of community wellbeing: A qualitative study of residents
Authors: Michalski Camilla , Ragunathan Apira , Foster Adrian , Pagalan Lief , Chu Casey , Diemert Lori M. , Helliwell John F. , Urajnik Diana , Speidel Ruth , Malti Tina , Fierheller Dianne , Fusca Laura , Zenlea Ian , McKean Scott , Rosella Laura C. 
Published: November 2023

Background
Understanding what promotes or hinders a community’s capacity to serve the priorities of its residents is essential for the alignment of citizen needs and governance. Participatory approaches that engage community residents on the topic of community wellbeing are useful methods for defining outcomes that reflect a community’s goals and priorities. Using qualitative focus group methods, the aim of this study was to outline bottom-up definitions of community wellbeing from a diverse pool of community residents in Ontario, Canada.

Methods
Semi-structured, two-hour group interviews were conducted with adult (≥18 years) participants (N = 15) residing in four communities across Canada’s largest province of Ontario. Participants were purposively selected from a pool of screening questionnaires to ensure diverse group compositions based on race, gender, age, and educational attainment. Interviews were thematically analysed using descriptive and interpretive methods to characterize resident conceptions of community wellbeing.

Results
Focus group participants were between 18 and 75 years of age and most had lived in their local community for 5 or more years. Four major themes emerged: (1) a sense of community belonging is cultivated through shared spaces, routines, support, and identities; (2) a community constitutes the amenities and social contexts that enable residents to thrive; (3) effective regional decision-making must be community-informed; and (4) the wellbeing of a community relies on equal opportunities for engagement and participation.

Conclusions
Residents described their communities and their associated wellbeing as a combination of accessible amenities and opportunities to engage without marginalization. This study underscores the value of participatory approaches in community wellbeing research, where the viewpoint and life experience of residents is used to inform local decision-making and service delivery. Future research will capture more diverse perspectives towards community belonging, particularly from community newcomers, for the development of regionally appropriate indicators of community wellbeing.
Geranylgeranylacetone reduces cardiomyocyte stiffness and attenuates diastolic dysfunction in a rat model of cardiometabolic syndrome
Authors: Waddingham Mark T. , Sequeira Vasco , Kuster Diederik W. D. , Dal Canto Elisa , Handoko M. Louis , de Man Frances S. , da Silva Gonçalves Bós Denielli , Ottenheijm Coen A. , Shen Shengyi , van der Pijl Robbert J. , van der Velden Jolanda , Paulus Walter J. , Eringa Etto C. 
Published: November 2023

AbstractTitin‐dependent stiffening of cardiomyocytes is a significant contributor to left ventricular (LV) diastolic dysfunction in heart failure with preserved LV ejection fraction (HFpEF). Small heat shock proteins (HSPs), such as HSPB5 and HSPB1, protect titin and administration of HSPB5 in vitro lowers cardiomyocyte stiffness in pressure‐overload hypertrophy. In humans, oral treatment with geranylgeranylacetone (GGA) increases myocardial HSP expression, but the functional implications are unknown. Our objective was to investigate whether oral GGA treatment lowers cardiomyocyte stiffness and attenuates LV diastolic dysfunction in a rat model of the cardiometabolic syndrome. Twenty‐one‐week‐old male lean (n = 10) and obese (n = 20) ZSF1 rats were studied, and obese rats were randomized to receive GGA (200 mg/kg/day) or vehicle by oral gavage for 4 weeks. Echocardiography and cardiac catheterization were performed before sacrifice at 25 weeks of age. Titin‐based stiffness (Fpassive) was determined by force measurements in relaxing solution with 100 nM [Ca2+] in permeabilized cardiomyocytes at sarcomere lengths (SL) ranging from 1.8 to 2.4 μm. In obese ZSF1 rats, GGA reduced isovolumic relaxation time of the LV without affecting blood pressure, EF or LV weight. In cardiomyocytes, GGA increased myofilament‐bound HSPB5 and HSPB1 expression. Vehicle‐treated obese rats exhibited higher cardiomyocyte stiffness at all SLs compared to lean rats, while GGA reduced stiffness at SL 2.0 μm. In obese ZSF1 rats, oral GGA treatment improves cardiomyocyte stiffness by increasing myofilament‐bound HSPB1 and HSPB5. GGA could represent a potential novel therapy for the early stage of diastolic dysfunction in the cardiometabolic syndrome.
Some notes on graded weakly 1-absorbing primary ideals
Authors: Alshehry Azzh Saad , Abu-Dawwas Rashid , Al-Rashdan Majd 
Published: November 2023

Abstract
A proper graded ideal

P

P

of a commutative graded ring

R

R

is called graded weakly 1-absorbing primary if whenever

x
,
y
,
z

x,y,z

are nonunit homogeneous elements of

R

R

with

0
≠
x
y
z
∈
P

0\ne xyz\in P

, then either

x
y
∈
P

xy\in P

or

z

z

is in the graded radical of

P

P

. In this article, we explore more results on graded weakly 1-absorbing primary ideals.
Fabrication and physicochemical characterization of copper oxide–pyrrhotite nanocomposites for the cytotoxic effects on HepG2 cells and the mechanism
Authors: He Yun , Huang Hua , Fan Minyu , Wang Zhaojiong , Liu Xiongwei , Huo Jiege 
Published: November 2023

Abstract
Novel CuO–FeS nanocomposites were synthesized to exert anticancer effects on HepG2 cells. The formation was initially demonstrated using UV–Visible spectrophotometry analysis, which indicated two peaks at 335 and 370 nm. Characteristic Fourier transform infrared spectroscopy peaks for Cu–O and Fe–S bonds were observed at 516, 577 and 619 cm−1 in addition to other notable peaks. The Miller indices correspond to the lattice spacing of monoclinic CuO and FeS as observed by selected area diffraction rings concurrent with the X-ray diffraction observations. The morphology was interpreted by scanning electron microscopy and transmission electron microscopy, indicating a particle size of 110 nm. As per energy-dispersive X-ray spectroscopy analysis, strong peaks for Cu (0.9, 8 and 9 keV), Fe (6–7 keV), O (0.5 keV) and S (2.5 keV) indicated the formation of CuO–FeS blend with no impurities. A mean particle size of 121.9 nm and polydispersity index of 0.150 were displayed by dynamic light scattering analysis and the zeta potential was −29.2 mV. The composites were not toxic to normal 3T3-L1 cells and were not haemolytic even at higher doses. In addition, the stable composites exerted cytotoxic effects on HepG2 cells (IC50 = 250 ± 5.7 μg/mL) and induced cell death by creating a loss in mitochondrial membrane potential and induction of mitochondrial apoptosis in a ROS-independent manner.
Formalisation of the sofware component ontology specification
Authors: Bagušytė Lina , Lupeikienė Audronė 
Published: November 2023

This paper is devoted to the development and specification problems of software component ontology. The formalisation of the proposed component ontology is presented, too. The choice of ontology interpretation is motivated. The paper discusses the content of the ontology specification and its development. The mereological theory of software component, one of the constituent parts of a formal component specification, is presented.
Analyse of students' assessment during final exams in secondary school and their first and second sessions in mathematics at Vytautas Magnus University and Kaunas Technical College
Authors: Rutkienė Aušra , Augutienė Elvyra 
Published: November 2023

The analysis of the of students’ assessment during final exams in secondary school and their first and second sessions at college and at university in mathematics was presented. Analysis demonstrates that students are not ready to work hard in case to get better marks at college and university. The students' grades are decreasing; but there is correlation between school grade and university's or college’s grade.
On the rate of convergence of degenerate U-statistics
Authors: Januškevičienė Olga 
Published: November 2023

Let X, X1, X2, ... be independent identically distributed random variables taking values in a measurable space (Ω, ℜ). Let h(x, y) be real valued measurable symmetric function of the arguments x, y ∈ ℜ.Assume that Eh(x, X)= 0, for all x. We consider U-statistics of type T = n−1 ∑1 ≤ i< k ≤ n h(Xi, Xk). Let qi, i ≥ 1 be eigenvalues of the Hilbert-Schmidt operator associated with the kernel h(x, y) and q1 be the largest eigenvalue. Under the condition β3 := E|h(X, X1)|3 <∞, we prove that Δn = ρ(T, T0) ≤ cβ3q−11 n−1/7 +cq−11∑i ≥ 1 qin−1/4, where T0 is the limit statistic and ρ is a Kolmogorov (or uniform) distance.
Investigation of outlier detection algorithm
Authors: Šaltenis Vydūnas 
Published: November 2023

The proposed outlier factor was used to analyze the multidimensional data sets regarding outlier detection. The paper describes two kinds of investigation: the influence of omitting some part of distances between data points, and the influence of additional (noisy) points to outlier detection quality. The results demonstrate the possibilities to improve the performance of computation and the stability of the outlier detection algorithm.
Solution of two-dimensional parabolic equation with nonlocal integral boundary conditions
Authors: Jakubelienė Kristina 
Published: November 2023

Two-dimensional parabolic equation with nonlocal integral boundary conditions in a rectangle domain in this paper is solved by alternating direction method. To ﬁnd the solutions of this problem we are looking to solve a linear system of equations. This algorithm is realized on particular example and assess the error of solution.