bluuebunny/crossref_metadata_2025_split huggingface dataset:
Qualitative Phytochemical Analysis of Gracilaria verrucosa from North Sulawesi Waters
Authors: Luringunusa Ekklesia , Sanger Grace , Sumilat Deiske A. , Montolalu Roike Iwan , Damongilala Lena J. , Dotulong Verly 
Published: October 2023

The research aims to determine the phytochemical content such as phenolics, flavonoids, tannins, saponins, alkaloids, steroids, and triterpenoids found in the seaweed G. verrucosa. Seaweed G. verrucosa taken from the waters of North Sulawesi, Nain Village, North Minahasa, was extracted by maceration for 24 hours at room temperature, repeated 3 times using 96% ethanol solvent. The analysis in this study consisted of seven test parameters such as phenolic compounds, flavonoids, tannins, saponins, steroids, triterpenoids, and alkaloids. The results of the analysis showed that the secondary metabolites of G. verrucosa contained phytochemical compounds such as phenols, flavonoids, tannins, saponins, steroids, and alkaloids, and no triterpenoid compounds were found. It was concluded that G. verrucosa which grows in the waters of North Sulawesi, Nain Village, can function as functional food, and medicine because it has natural bioactive compounds.
Keywords: Phytochemical content, Gracilaria verrucosa, secondary metabolites
Abstrak
Penelitian bertujuan mengetahui kandungan fitokimia seperti fenol, flavanoid, tanin, saponin, alkaloid, steroid, dan triterpenoid yang terdapat pada rumput laut G. verrucosa. Senyawa metabolit sekunder yang umum terdapat pada tanaman adalah senyawa terpenoid, alkaloid, fenolik, streroid, saponin, tannin. Rumput laut G. verrucosa yang di ambil dari perairan Sulawesi Utara Desa Nain Minahasa Utara di ekstraksi dengan cara maserasi selama 24 jam pada suhu ruang di ulangi sebanyak 3 kali menggunakan pelarut etanol 96 %. Analisis pada penelitian ini terdiri dari tujuh parameter pengujian seperti senyawa fenol, flavonoid, tanin, saponin, steroid, triterpenoid dan alkaloid. Hasil analisis menunjukan bahwa kandungan metabolit sekunder dari G. verrucosa mengandung senyawa fitokimia seperti fenol, flavonoid, tanin, saponin, steroid, alkaloid dan tidak ditemukan adanya senyawa triterpenoid. Hal ini disimpulkan bahwa G. verrucosa yang tumbuh di perairan Sulawesi utara Desa Nain dapat berfungsi sebagai pangan fungsional, obat-obatan karena memiliki senyawa bioaktif alami.
Kata kunci: Kandungan fitokimia, Gracilaria verrucosa, metabolit sekunder
Study of Planned Maintenance System Senior Admiral John Lie’s Training Ship on Shipping Safety
Authors: Ansar Azhar Ariansyah , Luasunaung Alfret , Sumilat Deiske Adeliene , Pamikiran Revols Dolfi Ch , Kaparang Frangky Erens , Onibala Hens 
Published: October 2023

The implementation of the ship maintenance management system on Rear Admiral Jhon Lie's training ship did not run optimally, which impacted the less-than-optimal condition of various training ship equipment because the crew did not carry out the ship maintenance system according to the procedure, resulting in the incident that the ship's anchor winch operation did not function optimally when the ship was anchored in Belang Port, Southeast Minahasa. This study aims to identify and analyze the positive and significant effect of the planned maintenance system on shipping safety. The primary data collection methods used in this study were questionnaires and interviews. In this study, data processing and presentation were in the form of diagrams and path analysis with structural equation modeling (SEM-PLS) using SmartPLS. From the results of the data analysis, the R-square value of shipping safety (Y) is 0.307, which means that the planned maintenance system (X1) and ship maintenance (X2) can affect shipping safety (Y) by 30.7%. Ship maintenance (X2) has a significant effect on sailing safety (Y), with P-values = 0.033 0.05 (hypothesis accepted). The planned maintenance system (X1) has a significant effect on sailing safety (Y), with a P-value of 0.037 0.05 (hypothesis accepted). As a result of the analysis, it was found that the planned maintenance system has a significant effect on shipping safety.
Pelatihan Model Pembelajaran Abad 21 dengan Flipped Learning untuk Guru SMA
Authors: Sunarto M.J. Dewiyani , Hariadi Bambang , Tan Amelia , Lemantara Julianto , Sagirani Tri 
Published: October 2023

Perkembangan jaman menuntut dunia pendidikan untuk lebih siap dalam menghadapi pembelajaran abad 21. Keterampilan yang dibutuhkan pada pembelajaran abad 21 diantaranya adalah berpikir kritis, kreatif, kolaboratif dan komunikatif. Tujuan pelatihan ini adalah agar pendidik dapat menyiapkan peserta didiknya untuk mempunyai kemampuan ketrampilan abad 21, melalui model Flipped Learning. Flipped Learning adalah model pembelajaran dimana komponen pendukungnya bersifat dapat melatih peserta didik untuk menguasai keterampilan abad 21. Pelatihan dilakukan secara webinar kepada guru di seluruh Indonesia, sejumlah 110 peserta. Metode yang digunakan adalah ceramah dan diskusi, dengan langkah pemberian pemahaman, gambaran dan praktik baik dari model Flipped Learning Setelah pelatihan, dilaksanakan evaluasi terhadap pelasanaan kegatan dengan menggunakan instrumen angket. Hasil jawaban peserta diolah dengan statistik deskriptif dan diperoleh nilai rata rata 3.67. Nilai tertinggi pada kualitas nara sumber dalam menyampaikan materi yaitu sebesar 3.8 dan nilai terendah pada efisiensi waktu penyelenggaraan, yaitu sebesar 3.5. Kesimpulan yang didapat adalah pendidik menyadari pentingnya Flipped Learning dan timbul kebutuhan untuk menerapkannya, sehingga rekomendasi yang diajukan adalah adanya pelatihan lanjutan berupa workshop pembuatan bahan ajar.
21st Century Education Model Training with Flipped Learning for High School Teachers
The development of the era requires the world of education to be better prepared to face 21st-century Learning. The skills needed in 21st-century Learning include critical thinking, creativity, collaboration and communication. This training aims for educators to prepare their students to have 21st-century skills, namely the Flipped Learning model. Flipped Learning is a learning model where the supporting components can train students to master 21st-century skills. The training was conducted in a webinar with teachers throughout Indonesia, with 110 participants. The method used is lectures and discussions, with steps to provide understanding, descriptions and good practices from the Flipped Learning model. After the training, an evaluation of the implementation of activities is carried out using a questionnaire instrument. The results of the participant's answers were processed with descriptive statistics and obtained an average value of 3.67. The highest score for the quality of the resource person in presenting the material is 3.8, and the lowest score is for efficiency in organizing time, which is 3.5. The conclusion obtained is that educators are aware of the importance of flipped Learning and the need arises to apply it, so the recommendations put forward are further training in the form of workshops on making teaching materials.
Menjaga Stabilitas Ekonomi Masyarakat Pasca Pandemi Covid-19 melalui Pelatihan Pembuatan Ranup (sirih) Hantaran bagi Ibu-ibu Desa Cot Girek Kec. Muara Dua
Authors: Maryana Maryana , Hikalmi Hikalmi , Keumala Cut Muftia , Safriani Irma , Mahmudan Mahmudan 
Published: October 2023

Pelaksanaan kegiatan pengabdian masyarakat melalui pelatihan pembuatan ranup hantaran di Gampong Cot Girek Kecamatan Muara Dua Kota Lhokseumawe bertujuan untuk memberikan solusi dalam menjaga stabilitas ekonomi pasca covid 19. Pelatihan ini dihadiri oleh 18 orang peserta dari warga Gampong Cot Girek Kec. Muara Dua. Para peserta dibagi menjadi 4 kelompok kecil untuk mempermudah dalam koordinasi saat pelatihan. Metode pengabdian dilakukan dengan cara observasi, diskusi, demonstrasi dan praktek langsung melalui tiga tahapan yakni perencanaan, pelaksanaan dan evaluasi. Hasil kegiatan ini mampu menambah wawasan, pemahaman dan keterampilan para perempuan di Gampong sehingga mampu memanfaatkan tanaman-tanaman yang ada disekitar lingkungan rumah untuk menghasilkan uang sehingga dapat mengatasi kesulitan ekonomi keluarga pasca covid 19. Disamping itu, dengan keterampilan yang dimiliki kaum ibu juga mampu memiliki kemandirian perekonomian yang memberi dampak pada kesejahteraan sosial.
Maintaining Community Economic Stability Post-Pandemic Covid-19 through Ranup (betel) Hantaran Making Training for the women of the village of Cot Girek district Muara Dua
The implementation of community service activities through training on making ranup hantaran in Gampong Cot Girek, Muara Dua District, Lhokseumawe City aims to provide solutions in maintaining economi stability post-covid 19. This training was attended by 18 participants from Gampong Cot Girek Kec. Muara Dua. The participants were divided into 4 small groups to facilitate coordination during the training. The service method is carried out by observation, discussion, demonstration and direct practice through three stages are planning, implementation and evaluation. The results of this activity are to be able to add insight, understanding and skills to women in Gampong so that they are able to use plants around their home environment to make money so they can overcome family economic difficulties post-covid 19. In addition, with the skills possessed by women, they are to be able to have economic independence which will then have an impact on social welfare
Pelatihan dan Pendampingan Pembukaan Rekening Online Bank Syariah Indonesia Mahasiswa Perbankan Syariah STEBIS IGM
Authors: Fadilla Fadilla , Suhendi Yusuf 
Published: October 2023

Teknologi digital saat ini mendominasi berbagai aspek kehidupan, termasuk perbankan syariah. Perbankan syariah berupaya memanfaatkan teknologi untuk memberikan kemudahan kepada nasabah, salah satunya dengan pembukaan rekening online melalui BUREKOL. Kami, sebagai dosen Perbankan Syariah, bekerja sama dengan Bank Syariah Indonesia untuk melatih mahasiswa dalam pembukaan rekening online. Pelatihan ini dilakukan pada 13 Maret 2023 di STEBIS IGM dengan 15 peserta. Metode pelatihan melibatkan contoh pembukaan rekening online yang dipraktikkan oleh seorang praktisi perbankan. Setelah pelatihan, 15 dari 17 mahasiswa memiliki rekening BSI dan mampu menggunakan mobile banking melalui smartphone mereka."
Training and Assistance in Opening Online Accounts for Bank Syariah Indonesia for STEBIS IGM Sharia Banking Students
Digital technology currently dominates various aspects of life, including sharia banking. Sharia banking seeks to utilize technology to provide convenience to customers, one of which is by opening an online account through BUREKOL. We, as Sharia Banking lecturers, collaborate with Bank Syariah Indonesia to train students in opening online accounts. This training was conducted on March 13 2023 at STEBIS IGM with 15 participants. The training method involves an example of opening an online account practiced by a banking practitioner. "After the training, 15 out of 17 students had BSI accounts and were able to use mobile banking via their smartphones.".
Pemberdayaan Kelompok Swadaya pengerajin Ukiran Bali “Anjatta” Dalam Mendukung Produksi Ukiran Di Desa Batubulan Kangin Kecamatan Sukawati
Authors: Putra I Komang , Wulandari IGA Athina , Putra Gede Sanjaya Adi 
Published: October 2023

Program Pengabdian Kepada Masyarakat (PKM) bertujuan meningkatkan kapasitas produksi kelompok swadaya pengerajin ukiran "Anjatta" di Desa Batubulan Kangin, Sukawati, Gianyar, untuk ekspansi pasar internasional. PKM juga bertujuan meningkatkan pengetahuan mereka dalam pengelolaan produksi dan keuangan. Metodenya melibatkan Focus Group Discussion (FGD) tentang produksi, ceramah tentang peluang ekspor, dan pelatihan pencatatan transaksi. Bantuan sarana produksi juga diberikan untuk meningkatkan produksi. Hasil observasi dan pengujian menunjukkan PKM membantu anggota Anjatta memahami pengelolaan produksi, keuangan, dan peluang ekspor serta meningkatkan produksi. Untuk keberlanjutan, disarankan melatih pemanfaatan market place dan e-commerce untuk penjualan internasional.
Empowerment Of Balinese Carving Craftsmen Self-Help Group In Supporting Increased Production In Batubulan Kangin Village, Sukawati District
The Community Service Program (PKM) aims to increase the production capacity of the self-help group of "Anjatta" carving craftsmen in Batubulan Kangin Village, Sukawati, Gianyar, for international market expansion. PKM also aims to increase their knowledge in production and financial management. The method involves Focus Group Discussions (FGD) about production, lectures about export opportunities, and transaction recording training. Assistance for production facilities is also provided to increase production. Observation and test results show that PKM helps Anjatta members understand production management, finance and export opportunities and increase production. For sustainability, it is recommended to train in the use of market places and e-commerce for international sales.
Cloze probability, predictability ratings, and computational estimates for 205 English sentences, aligned with existing EEG and reading time data
Authors: de Varda Andrea Gregor , Marelli Marco , Amenta Simona 
Published: October 2023

AbstractWe release a database of cloze probability values, predictability ratings, and computational estimates for a sample of 205 English sentences (1726 words), aligned with previously released word-by-word reading time data (both self-paced reading and eye-movement records; Frank et al., Behavior Research Methods, 45(4), 1182–1190. 2013) and EEG responses (Frank et al., Brain and Language, 140, 1–11. 2015). Our analyses show that predictability ratings are the best predictors of the EEG signal (N400, P600, LAN) self-paced reading times, and eye movement patterns, when spillover effects are taken into account. The computational estimates are particularly effective at explaining variance in the eye-tracking data without spillover. Cloze probability estimates have decent overall psychometric accuracy and are the best predictors of early fixation patterns (first fixation duration). Our results indicate that the choice of the best measurement of word predictability in context critically depends on the processing index being considered.
Жүктілік кезіндегі SARS-COV-2 короновирусты инфекцияның: Ана мен іштегі нәрестеге әсерінің нәтижесі
Authors: Кулбаева С.Н. , Жолымбекова Л.Д. , Саркулова И.С. , Омирбаева А.Т. , Тулегенова И.Ж. , Нурманова Н.Ж. , Сатов Д.Я. 
Published: October 2023

Өзектілігі: Мақалада өкпенің жалпы зақымдануы бар жүкті әйелдегі өте ауыр SARS-COV-2 инфекциясының қолайлы нәтижесінің клиникалық жағдайының талдауы сипатталған. Жүкті әйелдер бұл вирустарды тез жұқтырады, ауру ағымы да ауыр өтеді. Алайда, осыған қарамастан, өте ауыр ағымы бар жүкті әйелді уақтылы бағыттау SARS-COV-2 инфекциясы пациенттерге арналған жұқпалы аурулар ауруханасының акушерлік стационары SARS-COV-2 инфекциясы көп тәртіптік әдісті қолдана отырып мамандандырылған медициналық көмек көрсету мақсатында, осы патологиядағы ықтимал кардиологиялық асқынуларды есепке алу, оларды уақтылы диагностикалау және түзету ана мен ұрықтың нәтижесі қолайсыз жағдайлардың алдын алуға мүмкіндік берді.
Зерттеудің мақсаты – Шымкент қаласының қалалық перинаталдық орталығында орын алған клиникалық жағдайды сипаттау. Клиникалық жағдайды мысал ретінде пациентті жүргізу барысындағы әр кезеңінде бақылап, диагностика мен емдеу нәтижелерін баяндаймыз.
Материалдар мен әдістері: Шымкент қаласының қалалық перинаталдық орталығында SARS-CoV-2 ауыр түрімен ауырған жүкті әйел ауруханаға жатқызылды, ол ана мен ұрық үшін қолайлы нәтижемен аяқталды.
Нәтижелері: Осы мақалада біз қалалық инфекция орталығына түскен жүктіліктің 21-ші аптасындағы COVID-19 мен ауырып қалған жүкті әйелді емдеуді сипаттадық, ал бір аптадан кейін оның жағдайы нашарлаған кезде ол экстракорпоральды мембраналарды оттегімен қанықтыру үшін кардиоорталыққа ауыстырылды. Әйел одан әрі емдеу тактикасын анықтау үшін аппараттан ажыратылғаннан кейін 10 күн өткен соң, қалалық инфекция орталығына қайта жіберілді. Бір айдан кейін, науқастың жағдайы жақсарған кезде, ол ауруханадан шығарылды.
Жүктіліктің 41 аптасы, науқас дәрігерлердің бақылауымен 3 күн индукцияланды, сонымен қатар Апгар шкаласы бойынша 7 және 8 ұпайлары бар тірі толыққанды ұрықтың индукцияланған босануы болды. Босану асқынусыз болды.
Қорытынды: Жүкті әйелдердің респираторлық патогендерге төзімділігі төмен, сондықтан олар COVID-19 инфекциясына сезімтал болуы мүмкін. Сонымен қатар, жүктілік кезіндегі иммунологиялық өзгерістерге және COVID-19 инфекциясындағы цитокиндік шабуылдың ықтимал қауіптеріне байланысты жүкті әйелдер аурудың ауыр ағымына, тіпті өлімге әкелуі мүмкін.
Evaluation of Retinal Nerve Fiber Layer, Ganglion Cell Thickness, and Macular Thickness in Children With Comorbid Specific Learning Disorder and Attention-Deficit Hyperactivity Disorder
Authors: Tonkaz Gülsüm Yitik , Özyurt Gonca , Çakir Ali , Turan Bahadır , Utlu Bahadır , Özbay Ahmet Duhan 
Published: October 2023

Purpose:
To investigate the changes in ocular optical coherence tomography (OCT) findings in the comorbidity of attention-deficit hyperactivity disorder (ADHD) and specific learning disorder (SLD).

Methods:
This study included 40 individuals diagnosed as having ADHD along with comorbid SLD, 40 individuals diagnosed as having only ADHD, and 40 individuals with no psychiatric disorders. OCT assessments were performed on eyes of the participants to obtain retinal nerve fiber layer (RNFL) thickness, ganglion cell complex (GCC) thickness, and macular thickness measurements.

Results:

In total, 240 eyes were evaluated. The right and left eyes were not significantly different in terms of RNFL, GCL, and macular thickness within groups (
P
> .05). RNFL thickness was measured and compared across four quadrants (superior, inferior, temporal, and nasal). Although these values were not significantly different between the groups (
P
> .05), RNFL was observed to be thinner in children with comorbid ADHD and SLD in all quadrants. Similarly, GCL and macular thickness measurements were also not different between the groups (
P
> .05).

Conclusions:
Considering that retinal nerve fibers can be seen as an extension of the brain in the embryologic context, the results showed that OCT findings alone are not sufficient to detect the changes in ADHD and SLD comorbidity. The authors suggest that OCT is more useful in the etiology and follow-up of neurodegenerative diseases rather than neurodevelopmental disorders.

[
J Pediatr Ophthalmol Strabismus
. 2024;61(2):128–136.]
Influence of Natural Gas Pipeline Right-of-Ways on Eastern Red-Backed Salamander Occurrence in the Northern Appalachians
Authors: Brown Donald J. , Knopka Samuel C. , Grushecky Shawn T. , Owen Sheldon F. , Edwards John W. 
Published: October 2023

Abstract
Road and pipeline infrastructure development for natural gas extraction often results in forest fragmentation, which could negatively influence habitat quality for many amphibian species. We investigated occurrence dynamics of the eastern red-backed salamander Plethodon cinereus in relation to natural gas pipeline rights-of-way (ROWs) and forest structure characteristics in northern Pennsylvania, USA. We sampled 80 sites across two study areas by using coverboards, with each site containing sampling plots at the center of the ROW, the edge of the ROW, and 10 m and 30 m into the adjacent forest. We assessed the influence of ROW age, ROW width, distance from ROW, and five forest structure characteristics on plot occupancy probability. Eastern red-backed salamander occupancy probability decreased with ROW age and increased with distance from ROW. Our results indicate that eastern red-backed salamanders are negatively influenced by forest fragmentation for natural gas ROWs. Moreover, responses were time dependent, with occupancy probability declining with ROW age. Due to low detections, we were unable to analyze data for the other amphibians and reptiles encountered during the study. Our capture data indicate that ROWs could improve habitat quality for some snake species, but additional research is needed to better understand the influence of ROWs on reptile species. To reduce future forest fragmentation and impacts on eastern red-backed salamander populations, managers could consider placing pipelines along existing linear clearings and enhancing the habitat quality of ROWs for salamanders.
Sur le seuil de la prison de Laon
Authors: Génard Elsa 
Published: October 2023

À partir d’un corpus de 605 individus écroués entre 1912 et 1939 dans la maison de correction de Laon, cet article propose conjointement une sociographie des condamnés et une analyse de leurs modalités d’incarcération. Après avoir montré que les prisonniers et les prisonnières appartiennent aux classes populaires défavorisées de l’Aisne, l’article s’attache à décrire les clivages qui structurent la population pénitentiaire laonnoise. À un groupe particulièrement désaffilié s’oppose un ensemble d’individus pouvant témoigner de gages d’insertion sociale. Ces distinctions socio-pénales permettent, dans un second temps, d’éclairer les différentes voies qui mènent aux portes de la prison de Laon. Quatre types d’entrée sont distingués, en fonction de la vitesse d’exécution des décisions judiciaires et de la présence ou non d’un agent des forces de l’ordre. La détention préventive, la coercition rapide, la coercition retardée et la constitution volontaire dessinent une gamme élargie de l’expérience du pouvoir de l’État dans la France du premier XXe siècle. Loin de se réduire à l’application mécanique d’une procédure, l’incarcération apparaît comme une pratique sociale qui n’offre pas les mêmes marges de manœuvre à tous les individus.
HLA-DQ8 Supports Development of Insulitis Mediated by Insulin-Reactive Human TCR-Transgenic T Cells in Nonobese Diabetic Mice
Authors: Racine Jeremy J , Misherghi Adel , Dwyer Jennifer R , Maser Richard , Forte Elvira , Bedard Olivia , Sattler Susanne , Pugliese Alberto , Landry Laurie , Elso Colleen , Nakayama Maki , Mannering Stuart , Rosenthal Nadia , Serreze David V 
Published: October 2023

Abstract
In an effort to improve HLA-“humanized” mouse models for type 1 diabetes (T1D) therapy development, we previously generated directly in the NOD strain CRISPR/Cas9-mediated deletions of various combinations of murine MHC genes. These new models improved upon previously available platforms by retaining β2-microglobulin functionality in FcRn and nonclassical MHC class I formation. As proof of concept, we generated H2-Db/H2-Kd double knockout NOD mice expressing human HLA-A*0201 or HLA-B*3906 class I variants that both supported autoreactive diabetogenic CD8+ T cell responses. In this follow-up work, we now describe the creation of 10 new NOD-based mouse models expressing various combinations of HLA genes with and without chimeric transgenic human TCRs reactive to proinsulin/insulin. The new TCR-transgenic models develop differing levels of insulitis mediated by HLA-DQ8–restricted insulin-reactive T cells. Additionally, these transgenic T cells can transfer insulitis to newly developed NSG mice lacking classical murine MHC molecules, but expressing HLA-DQ8. These new models can be used to test potential therapeutics for a possible capacity to reduce islet infiltration or change the phenotype of T cells expressing type 1 diabetes patient-derived β cell autoantigen-specific TCRs.