bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hierarchical Clustering of the European Countries from the Perspective of E-government, E-participation, and Human Development
Authors: Androniceanu Armenia , Georgescu Irina 
Published: December 2023

Abstract
The information society offers governments the opportunity to work closer with citizens and companies, to respond better to their requirements, and to create the conditions for the functioning of a modern, efficient, and democratic public administration. Due to the development of the information society, e-governance and e-participation appeared and developed, through which the communication of governments with stakeholders became more straightforward and less expensive. This research aims to identify and analyse comparatively how the telecommunications infrastructure and Internet users influenced the expansion and diversification of e- government and e-participation that contributed to the human development index in the EU states in 2010-2022. In the longitudinal data analysis, we apply fixed and random estimators to see the most critical determinants of the human development index. In the second part, we cluster the 27 EU countries in four clusters by Ward’s hierarchical algorithm. The hierarchical clustering emphasised that there is still a digital divide among EU countries. The digital divide occurs because of the lack of Internet access of the population from marginalised communities of European countries, resulting in socio-economic disparities. Therefore, some EU states should have initiatives to bridge the gap to digital technologies. The research results are essential for those governments coordinating the policies and the entire process of integrating information technologies and dedicated e-government and e-participation applications in central and local administration.
Comorbid Conditions in a Cohort of Inpatients with SARS-CoV-2 and their Association with In-Hospital Mortality During the Early Phases of the Pandemic
Authors: Dokic Dejan , Cibrev Dragan , Danilovski Dragan , Chamurovski Nikola , Karajovanov Ivana Dohcheva , Karanfilovski Vlatko , Stefanovski Goran , Klenkoski Suzana , Arnautovska Bogdanka , Barbov Ivan , Zeynel Sead , Stardelova Kalina Grivcheva , Rambabova-Bushljetik Irena , Nikolovska Suzana , Netkovski Jane , Duma Hristijan 
Published: December 2023

Abstract

Introduction: Studies determined that age and associated comorbidities are associated with worse outcomes for COVID-19 patients. The aim of the present study is to examine previous electronic health records of SARS-CoV-2 patients to identify which chronic conditions are associated with in-hospital mortality in a nationally representative sample.

Materials and Methods: The actual study is a cross-sectional analysis of SARS-CoV-2 infected patients who were treated in repurposed hospitals. The study includes a cohort of patients treated from 06-11-2020 to 15-03-2021 for COVID-19 associated pneumonia. To examine the presence of comorbidities, electronic health records were examined and analyzed.

Results: A total of 1486 in-patients were treated in the specified period, out of which 1237 met the criteria for case. The median age of the sample was 65 years. The overall in-hospital mortality in the sample was 25.5%, while the median length of stay was 11 days. From whole sample, 16.0% of the patients did not have established diagnoses in their electronic records, while the most prevalent coexisting condition was arterial hypertension (62.7%), followed by diabetes mellitus (27.3%). The factors of age, male gender, and the number of diagnoses showed a statistically significant increase in odds ratio (OR) for in-hospital mortality. The presence of chronic kidney injury was associated with the highest increase of OR (by 3.37) for in-hospital mortality in our sample.

Conclusion: The study reaffirms the findings that age, male gender, and the presence of comorbidities are associated with in-hospital mortality in COVID-19 treated and unvaccinated patients. Our study suggests that chronic kidney injury showed strongest association with the outcome, when adjusted for age, gender, and coexisting comorbidities.
Effectiveness of Ropeginterferon Alfa-2B in High-Risk Patients with Philadelphia Chromosome Negative Myeloproliferative Neoplasms– Evaluation of Clinicohaematologic Response, and Safety Profile: Single Centre Experience
Authors: Popova-Labachevska Marija , Cvetanoski Milche , Ridova Nevenka , Trajkova Sanja , Stojanovska-Jakimovska Simona , Mojsovska Tara , Stojanoski Zlate , Pivkova-Veljanovska Aleksandra , Panovska-Stavridis Irina 
Published: December 2023

Abstract

Background: Treatment of Philadelphia chromosome negative myeloproliferative neoplasms (Ph – MPNs) requires individualized approach depending on multiple factors. Novel pegylated Interferon (IFN) formulations have become an attractive therapeutic option in young Ph- MPN patients associated with better patient compliance.

Methods: In this retrospective observational study a total of 16 high-risk Ph- MPN patients treated off-label with ropeginterferon alfa-2b given twice monthly, were included. Median follow-up was 24 months. High-risk patients were defined using the IPSET score. Response to treatment was evaluated using ELN, IWG-MET EUMNET standardized criteria and occurrence of side effects was documented.

Results: 11 patients were female (68.8%) and 5 male (31.2%); average age at diagnosis was 36 years (17-51); 12 patients (75%) had ET, one (6.2%) PV and three (18.8%) hypercellular phase of PMF. JAK2V617F mutation was detected in 10 patients (62.5%), CALR in three (18.8%), and three (18.7%) were triple-negative cases. In 7 patients (43.7%), ropeginterferon alfa-2b was used in first-line, and 9 (56.3%) were previously treated with HU and/or standard IFN. Among initially ropeginterferon alfa-2b treated patients, complete haematological response was observed in 4/7 (57.1%), partial in 2/7 (28.6%) and suboptimal in one (14.3%). Complete haematological response was observed in 8/9 (88.9%) among previously treated patients. Average time to blood count normalization was 8 weeks, at a dose ranging between 100mcg and 300mcg. Side effects were observed in one patient (6.2%).

Conclusion: Our experience is in support of previous studies regarding ropeginterferon alfa-2b efficacy and safety profile in the treatment of young patients with Ph- MPNs.
Compound Heterozygosity in Cerebellar Ataxia, Mental Retardation, and Disequilibrium Syndrome Type 4
Authors: Teov Bojan , Janchevska Aleksandra , Beqiri-Jasari Ardiana , Tasic Velibor , Kungulovski Goran , Gucev Zoran 
Published: December 2023

Abstract
Cerebellar ataxia, mental retardation, and disequilibrium syndrome (CAMRQ) is a genetically and clinically heterogeneous disorder with four described subtypes. Autosomal recessive syndrome of cerebellar ataxia, mental retardation, and disequilibrium type 4 (CAMRQ4) is caused by mutations in the ATP8A2 gene. We report an 8-year-old boy with choreoathetosis, hypotonia, without the ability to keep his head up and profound mental retardation. There was quadrupedal locomotion, as well. MRI of the brain revealed a hypotrophy of the corpus callosum, diffuse white matter reduction, widespread delayed myelination and ventriculomegaly. Trio whole-exome sequencing revealed compound heterozygosity in the ATP8A2 gene consisting of a known variant c.1756C>T (p.Arg586*) inherited from the mother and a novel variant c.691_701delCTGATGAAGTT (p.Leu231fs) inherited from the father. CAMRQ type 4 has been found in about 50 patients. To the best of our knowledge, this is the first reported patient with CAMRQ4 with these gene variants. The clinical presentation is severe.
Peran Pemerintah Daerah Kota Dumai Provinsi Riau Dalam Penguatan Program Pemberdayaan Sosial Dan Penanganan Warga Negara Migran Korban Tindak Kekerasan
Authors: Latif Syahrul Akmal , Febrian Ranggi Ade , Rahman Raden Noor Faizh 
Published: December 2023

Tujuan penelitian ini untuk mengetahui peran Dinas Sosial dan Pemberdayaan Masyarakat Kota Dumai dalam penguatan sosial kemasyarakatan. Permasalahan dalam peneltian ini adalah kegiatan rehabilitasi sosial dasar penyandang disabilitas terlantar, anak terlantar, lanjut usia terlantar, serta gelandangan pengemis di luar panti sosial dan penanganan warga negara migran korban tindak kekerasan dihadapkan pada terbatasnya anggaran. Metode penelitian yang digunakan dalam penelitian ini adalah kualitatif eksploratif dengan pendekatan studi kasus yang terjadi di tingkat daerah dengan menggunakan toeri peranan menurut Levinson yaitu norma, personal, dan stuktur. Hasil penelitian ini menunjukkan bahwa pertama norma mengacu pada Visi dan Misi Kepala Daerah dan Wakil Kepala Daerah merupakan pandangan ke depan yang menggambarkan arah, dan tujuan yang ingin dicapai guna menyamakan komitmen seluruh pihak yang berkepentingan dalam menjalankan roda pemerintahan dan melaksanakan pembangunan Kota Dumai. Kedua, terdapat program Kegiatan Rehabilitasi Sosial Dasar Penyandang Disabilitas Terlantar, Anak Terlantar, Lanjut Usia Terlantar, serta Gelandangan Pengemis di Luar Panti Sosial 54,80% dari anggaran. Ketiga, Pemerintah Kota Dumai melalui Dinas Sosial dan Pemberdayaan Masyakat pada tahun 2022 telah menganggarkan untuk program penanganan warga negara migra senilai Rp. 4.699.507,- dengan realisasi penyerapan anggaran Rp. 4.486.000,- atau 95,46% yang dialokasikan melalui kegiatan dan sub kegiatan. Kesimpulan penelitian ini Pemerintah Daerah Kota Dumai melalui Dinas Sosial dan Pemberdayaan Masyarakat berperan dalam meningkatkan kesejahteraan sosial terutama pada program permberdayaan sosial dan penanganan warga negara korban kekerasan.
اللهجة الموصلية وأثرها اللغوي والثقافي دراسة تحليلية في الأصول والمؤثرات
Authors: YASEEN Mohammed.abdulkareem 
Published: December 2023

تهدف هذه الدراسة إلى مناقشة عدة قضايا، من أهمها التعريف باللهجة الموصلية وكيفية نشأتها ومصدرها وما هو الأصل اللغوي لها، وكذلك دراسة تأثيرها على اللهجات العراقية الأخرى. إن اللهجة الموصلية تتميز بنطق صوتي يختلف تماماً عن باقي اللهجات العراقية، وهذا الاختلاف كان سببًا في تأثر تلك اللهجات بها بسبب انتقال النطق الصوتي بينها. علاوة على ذلك، تأثرت اللهجة الموصلية بشكل واضح من خلال استعمال ألفاظ متعددة مستمدة من لهجات ولغات أخرى. تأتي اللغة التركية بوضوح كأحد اللغات التي تأثرت بها اللهجة الموصلية بشكل كبير. يعكس هذا التأثر العلاقات والروابط التي تربط اللهجات العراقية مع بعضها البعض وبين اللهجات العربية القديمة. وترجع هذه التأثيرات جزئياً إلى قرب الرقعة الجغرافية لمدينة الموصل من تركيا والدول المجاورة الأخرى، بما في ذلك اللغة الفارسية. وفي هذا السياق، يتعامل هذا البحث مع تأثير اختلاط الثقافات التركية والعربية والفارسية على اللهجة الموصلية وتحليل النتائج من النواحي الصوتية والدلالية. بالإضافة إلى ذلك، حيث يهدف هذا البحث إلى استكشاف لهجة الموصلية والتركيز على تأثيراتها وتفاعلاتها اللغوية مع اللهجات العراقية الأخرى. تتميز اللهجة الموصلية بنطق صوتي فريد يختلف تمامًا عن لهجات العراق الأخرى، مما أدى إلى تأثيرها على تلك اللهجات من خلال تبادل النطق الصوتي. بالإضافة إلى ذلك، تعرضت اللهجة الموصلية لتأثيرات لغوية متعددة نتيجة استيعاب كلمات ومفردات من لهجات ولغات متعددة. تقدم الدراسة تحليلًا عميقًا للتقارب اللفظي والدلالي بين اللغة التركية ولهجة الموصلية، بمراجعة اللهجة الموصلية من النواحي الصوتية والدلالية. وتسلط الضوء أيضًا على الآثار الاجتماعية والثقافية لهذا التفاعل اللغوي، مما يعزز فهمنا للتقاربات اللسانية والثقافية في المنطقة.
بشكل عام، يُظهر هذا البحث كيف يمكن للغة أن تكون وسيلة للتواصل والتفاعل الثقافي بين مجتمعات مختلفة، مع التركيز على الدور البارز الذي لعبته اللهجة الموصلية وتأثير اللغة التركية عليها.
Sustainability Assessment of Tourism Destinations from the Lens of Green Digital Transformations
Authors: Streimikiene Dalia 
Published: December 2023

The rapid expansion of tourist destinations has important environmental, climate change, and socioeconomic impacts on countries. The main objectives of the paper are: to analyze sustainable tourism concepts, indicators, and frameworks of sustainability assessment in tourism; to develop a framework for sustainable tourism assessment of tourist destinations; to apply a developed framework for sustainability assessment of tourism destinations in Visegrad countries (Czech Republic, Hungary, Poland, and Slovakia) from the lens of green, digital transformations and boosting social-economic resilience. These are crucial policy pillars due to experiences during the COVID-19 pandemic. The main methods and data applied: several MCDM tools were applied to rank Visegrad countries on the progress achieved in sustainable tourism development. The data on indicators of the EU Tourism Dashboard were applied. The results of the ranking indicated that the best-performing country in terms of sustainable tourism development was Poland, following Hungary, the Czech Republic, and Slovakia. The main reason for this was the best results in digitalization and social-economic resilience shown by Poland and Hungary. The main policy implications for these countries are linked to the enhancement of environmental impact mitigation policies in tourism. The main contribution of this paper is a sustainability assessment of tourism destinations in Visegrad countries based on policy priorities and the newest available data by applying advanced MCDM tools.
Deteksi Parasit Darah pada Sapi Bali di Balai Pembibitan Ternak dan Hijauan Makanan Ternak di Pulau Sumbawa
Authors: Kholik Kholik , Qadriyah Deta Ramdani , Supriadi  , Atma Candra Dwi , Riwu Katty Hendriana Priscilia , Rahmawati Septyana Eka 
Published: December 2023

Tujuan Penelitian ini adalah untuk mendeteksi infeksi parasit darah pada sapi Bali di Balai Pembibitan Ternak dan Hijauan Makanan Ternak Serading di pulau Sumbawa. Metode penelitian ini menggunakan studi cross sectional survey dengan desain penelitian epidemiologi deskriptif yang berbasis perhitungan. Survei parasit darah pada sapi Bali dilakukan pada pada bulan Maret tahun 2023. Penelitian ini menggunakan 17 sampel darah sapi Bali yang diambil secara acak dengan metode simple random sampling. Sampel darah diambil dari vena Auricularis sapi Bali untuk dibuat apusan darah dan diwarnai dengan pewarnaan Giemsa untuk diamati menggunakan mikroskop dengan perbesaran 1000x. Hasil penelitian menunjukan bahwa 17,64 % sapi Bali di Balai Pembibitan Ternak dan Hijauan Makanan Ternak Serading terinfeksi parasit darah. Parasit darah yang terdeteksi menginfeksi sapi Bali tersebut adalah Anaplasma sp dengan prevalensi 11,76 % dan Trypanosoma sp 5,88%. Berdasarkan hasil penelitian dapat disimpulkan bahwa sapi Bali di Balai Pembibitan Ternak dan Hijauan Makanan Ternak Serading telah terdeteksi terinfeksi parasit jenis Anaplasma sp dan Trypanosoma sp dengan prevalensi yang rendah.
Using pumice as an alternative to reduce biological oxygen demand and chemical oxygen demand in tough waste
Authors: Sholehah Hijriati , Abdullah Taufik , Azwarudin  , Aprianti Sri 
Published: December 2023

The tofu industry is a type of industry that operates in the field of food processing from soybean raw materials. The tofu industry is dominated by small-scale businesses, most integrated into residential areas. The tofu industry has yet to process the liquid waste it produces. High environmental pollution can result in the death of aquatic biota due to lack of oxygen. This research aims to reduce BOD and COD levels that do not meet quality standards. Based on this, research was conducted to reduce the organic content in tofu liquid waste using pumice stone as a filtration medium. The research used a 2.5-inch PVC pipe with a height of 70 cm and a media size of 8 mesh, which was heated at temperatures of 50°C and 100°C. The research results after treatment showed that the initial concentration of BOD levels was 160 mg/L. After going through the filtration process with media heating treatment at 50°C and 100°C, the BOD levels were reduced to 116.8, 76.8, and 40 mg/L, respectively, with 52% and 75% reduction effectiveness. While the initial concentration of COD levels was 326 mg/L, after going through the filtration process with media heating treatment at 50°C and 100°C, the COD levels were reduced to 252 and 198 mg/L, respectively, and the effectiveness of the reduction was 23% and 39%.
Deus, uma atenção
Authors: Marques Bárbara Romeika Rodrigues 
Published: December 2023

O presente estudo discute em que medida a relação com o sagrado potencializa o elo ético-político do ser no mundo. A partir da indissociabilidade entre a experiência de vida e a obra de Simone Weil, pergunta por uma atenção à graça divina que possibilite intermediar o sentir e o agir e consolide a atitude insurgente frente à barbárie do mundo moderno. Apresenta a hipótese de uma experiência atencional que é, ao mesmo tempo, familiarização da consciência com a beleza das formas da natureza, afirmação da pluralidade e resguardo de um ethos de amor e paz. “Só a atenção religiosa é a atenção plena”, afirma Simone Weil. Desta perspectiva, o estudo desenvolve a ideia de que a oração e a atenção constituem a mesma faceta de um desejo de encontro com o sagrado: a fortuna de tomar a contradição como elemento divino, a graça de sintonizar transcendência e afirmação da vida, na compaixão e no significado de amor ao próximo.
Abstract: The present study discusses the extent to which the relationship with the sacred enhances the ethical-political bond of being in the world. From the indissociability between the life experience and the work of Simone Weil, it seeks to ask for an attention to divine grace that makes it possible to mediate feeling and acting and consolidates the insurgent attitude towards the barbarism of the modern world. It presents the hypothesis of an attentional experience that is, at the same time, familiarization of the conscience with the beauty of the forms of nature, affirmation of plurality, and protection of an ethos of love and peace. “Only religious attention is mindfulness”, says Simone Weil. From this perspective, the study seeks to develop the idea that prayer and attention constitute the same facet of a desire to encounter the sacred: the fortune of taking contradiction as a divine element, the grace of tuning into transcendence and affirmation of life, in compassion and the meaning of love for others.
Keywords: Simone Weil; Sacred; Attention; God.
Católicos contra a fraternidade
Authors: Gripp Glícia 
Published: December 2023

Este artigo examina os ataques contra as Campanhas da Fraternidade, protagonizados por grupos católicos laicos da nova extrema direita ou neointegristas. A partir do enfoque da sociologia da cultura, qualitativo, coletou-se os dados das redes sociais das lideranças e dos ativistas dos grupos. A interpretação dos dados foi realizada com a metodologia de análise de conteúdo, na identificação de padrões na comunicação. Na conclusão, observa-se que os grupos estudados produzem e reproduzem um conjunto de pressupostos, tomados como certos, que guiam, intuitivamente, a ação de seus membros, a partir de uma compreensão da fraternidade restrita àqueles que possuem os mesmos pressupostos.
Abstract: This article examines the attacks against the Fraternity Campaigns, carried out by Right-wing Catholic extremists. Based on the sociology of culture approach, data were collected from the social networks of its leaders and activists. Content analysis was used in data processing, identification of patterns in communication on social networks. In conclusion, it is observed that the studied groups produce and reproduce a set of assumptions, taken for granted, that intuitively guide the action of their members, based on an understanding of fraternity restricted to those who have the same assumptions.
Keywords: Fraternity; Fraternity Campaigns; Right-wing catholic extremists; Integrism; Sociology of culture.
Prevalence of Permethrin Resistance in Culex Tarsalis Populations in Southern California
Authors: Tsecouras Julie C. , Thiemann Tara C. , Hung Kim Y. , Henke Jennifer A. , Gerry Alec C. 
Published: December 2023

ABSTRACT
In the western United States, Culex tarsalis is the most important vector of West Nile virus. Insecticides containing permethrin or other pyrethroid compounds are commonly used to control these mosquitoes. Because of the range of environments where Cx. tarsalis are found, this species is under insecticide pressure from both vector control and agricultural spraying. Mosquito populations may evolve resistance through mechanisms such as target site insensitivity, including the frequently identified knockdown resistance (kdr) mutations. Prevalence of permethrin resistance was determined for Cx. tarsalis from 5 southern California field sites representing 2 distinct valley regions (Coachella Valley and Inland Valley), which are geographically separated by the north-south-running Peninsular Mountain Ranges. These two valley regions are &gt;100 km apart and vary considerably in their environmental and habitat characteristics. Permethrin resistance in mosquito populations was determined by the Centers for Disease Control and Prevention (CDC) bottle bioassay, using glass bottles coated with permethrin at 0.19 μg/cm2 of internal surface. Permethrin resistance was evident in Cx. tarsalis populations from the Coachella Valley field sites with all sites showing similar mortality in the bottle bioassay, while Cx. tarsalis from the Inland Valley field sites were largely susceptible to permethrin, with mortality rates that were similar to a susceptible lab strain of Cx. tarsalis.
Temperature Influence on Aedes aegypti Oviposition in the San Joaquin Valley of California
Authors: Hernandez Eunis , Salim Kasem , Joyce Andrea 
Published: December 2023

ABSTRACT
The establishment and oviposition of Aedes aegypti can vary from one location to another partially due to differing temperature and precipitation. In 2017, Ae. aegypti was first detected in Merced in the Central Valley of California. The objectives of this study were to examine the influence of temperature and precipitation on oviposition of Ae. aegypti, and to determine the beginning and end of the seasonal activity of Ae. aegypti in Merced. The study site consisted of a residential area in the north-east region of Merced where Ae. aegypti was first detected in Merced County. Fifty-four residences were randomly selected as ovitrap sites. Ovitraps were placed at field sites weekly for 12 months, from September 27, 2017, to September 27, 2018. Each week, ovitraps were inspected for the presence of mosquito eggs. Egg counts were used to calculate the following oviposition indices: the ovitrap index (OI) (percent of traps positive) and the egg density index (EDI) (eggs/positive traps). Oviposition occurred primarily from May through October, above a minimum temperature of 10°C, and when almost no rainfall occurred (0.5 mm total). During the year, the percent of positive traps per month ranged from approximately 1.2–67.3%, with highest values in June to October (43.9–67.3%). The highest mean monthly EDI was from July to October (34–44.6) and peaked in October at 44.6 eggs/trap. The EDI values are similar to other locations where Ae. aegypti transmits endemic vector-borne disease. These findings provide baseline data for Ae. aegypti control in Merced and the Central Valley of California.