bluuebunny/crossref_metadata_2025_split huggingface dataset:
Telerehabilitation As An Opportunity In Physiotherapy:
Authors: Collebrusco Luca , Tesauri Daniele 
Published: October 2023

Telerehabilitation (TR) represents a new opportunity for physiotherapists to provide acceptable and high quality healthcare to their service users. The emerging evidence in the literature suggests the opportunity to integrate TR into the physiotherapy professional practice, even beyond the COVID-19 emergency, to ensure continuity of care up to the patient’s home and increase access to rehabilitation. One of the areas of application of TR is the management of non-specific low back pain (NLBP). NLBP has a high prevalence rate in the global population and it represents approximately 90% of low back pain cases. It is associated with the risk of chronicization, if not adequately managed, and extremely high costs associated with the treatment. Objective: to develop a proposal for a diagnostic-therapeutic care path (DTCP) on the use of TR in the management of patients with low back pain, taking into consideration the Italian legislation and the best scientific evidence available in the literature. Materials and methods: the bibliographical research in the literature was carried out on the electronic databases MEDLINE, PEDro, Embase, Trip database and Google Scholar was used to access the full-text of some articles. Discussion: the proposed DTCP for the management of the patient with low back pain takes into account the strengths and limitations of TR described in the literature and may represent a national reference model for the application of TR in patients with NLBP who access the outpatient territorial rehabilitation service. However, this proposal needs to be adapted to the specific socio-legislative regional context.
ANALYSIS AND EVALUATION OF THE IMPACT OF COVID-19 ON THE COMPLEX SYSTEM OF THE 19 TSRM AND PSTRP HEALTH PROFESSIONS.
Authors: Nissi Claudia 
Published: October 2023

In the pandemic emergency, work-related stress in paramedical professions has reached levels never imagined before.
A questionnaire was administered to understand the stress or burnout, generated by the Covid 19 pandemic.
The psychological theory reported explains the results that emerged and the correlations with the factors that intensified the impact of stress, to produce burnout situations among health professionals.
DEVELOPMENT STAGES, OPPORTUNITIES AND PERSPECTIVES OF THE INSURANCE MARKET IN GEORGIA
Authors: Tchiotashvili David , Chitadze Khaliana 
Published: October 2023

Of course, the development and expansion of the insurance market is one of the important and solid foundations of the development of the financial market of Georgia, because the effective development of the insurance market is a decisive factor for the insurance protection and economic security of the society. It also significantly contributes to the development of production processes and business in the conditions of market relations, so the study and detailed review of the insurance market allows to see the current challenges and ways to solve them.
The main goal of the paper is to study and investigate the role and importance of the insurance market in Georgia. Despite the already achieved significant successes and results, the problem lies in the fact that in Georgia, both the financial market and its component insurance market are still in the process of formation and cannot fully ensure the satisfaction of complex insurance needs of customers with different needs and global insurance protection.
The paper analyzes the stages of formation, formation and development of the insurance market in Georgia, state regulation of the insurance market, formation and development of important insurance programs supported by the state, such as: universal health insurance and agroinsurance; Challenges and problems facing the insurance market.
ВПЛИВ ЗАСОБІВ МАСОВОЇ ІНФОРМАЦІЇ НА ВИБОРЧИЙ ПРОЦЕС В УКРАЇНІ
Authors: Степаненко Микола , Старченкова Анастасія 
Published: October 2023

Статтю присвячено аналізові впливу засобів масової інформації на виборчий процес в Україні, яка пережила за останні роки суттєві революційні зміни та політичні реформи; схарактеризовано роль телебачення, радіо, газети, інтернет-ресурсів і соціальних мереж у формуванні виборчих уподобань та поведінки виборців; особливу увагу приділено використанню соціальних мереж як знакового важеля впливу на громадську думку й технологію маніпулювання виборчими настроями; доведено, що сучасне законодавство у сфері агітації слід модернізувати, аби домогтися забезпечення рівних прав та рівних можливостей для учасників виборчого процесу й цим ефективно протидіяти зловживанням під час виборів та швидкого й результативного реагування на виклики інформаційного суспільства; виокремлено спектр причин, які конституюють методологійні засади процесу еволюції виборчого законодавства: виняткову увагу приділено задекларованому в меті дослідження впливу засобів масової інформації, по-перше, на виборчий процес в Україні й політичні уподобання та поведінку виборців, по-друге, на формування громадської думки, політичних агенд та образів кандидатів під час виборчих кампаній, по-третє, на виявлення можливих ризиків медійної маніпуляції і спотворення інформації; зроблено спробу встановлення корелятивних відношень на рівні стратегічної законодавчої бази, яка стосується специфіки організації та проведення виборів.
КОНЦЕПТ TRAV EL JOURNEY ) У СУЧАСНІЙ АНГЛІЙСЬКІЙ МОВІ: СМИСЛОВА СТРУКТУРА СУБКОНЦЕПТІВ ROAD І W AY (НА МАТЕРІАЛІ ТЛУМАЧНИХ СЛОВНИКІВ)
Authors: Колонюк Сергій , Космеда Т. 
Published: October 2023

Дослідження мовних засобів об’єктивації концептів є одним з найефективніших способів проникнення в концептосферу носіїв мови задля виявлення її специфічних рис, осмислення світорозуміння та поведінки людей певного етносу. Важливість виявлення смислової структури концепту TRAVEL (JOURNEY) в сучасній англійській мові сприятиме встановленню характерних ознак англійської лінгвокультури.
АЛЕТИЗАЦІЯ НІГІЛІЗМУ М. ГАЙДЕҐЕРОМ
Authors: Захлипа Дар’я , Прокопенко Володимир 
Published: October 2023

Феномен нігілізму в історії філософської думки прийнято пов’язувати із фігурою Ф. Ніцше, незважаючи на те, що його підоснови у вигляді негації були прочинені іще Ф. Гегелем [1]. Їхній водорозділ можна цілком виправдано провести по лінії, яка різнить логіку та формальне заперечення з аксіологією та запереченням дещо як цінності в цілому. При цьому навіть в рамцях двох аксеологічно спрямованих варіантів нігілізму є сенс вирізняти окремо заперечення метафізичних цінностей й заперечення буття як цінності. Що до екзистенціальної аналітики М. Гайдеґера, то вона сповнила феномен нігілізму контекстом, вкоріненим у свідомості Das Man: забуття та покинутості, які зрештою, починаючи з 30-х років, стали майже повністю ототожнюватись Гайдеґером. І саме цей факт вирішальним чином вирізняє його онтологічний проект з-поміж нігілістичних проектів Гегеля та Ніцше.
РОЛЬ ІНФОРМАЦІЙНО-ЦИФРОВОЇ КОМПЕТЕНТНОСТІ ВИКЛАДАЧА ХІМІЧНИХ ДИСЦИПЛІН У СТВОРЕННІ ІНФОРМАЦІЙНО-ОСВІТНЬОГО СЕРЕДОВИЩА ЗВМ(Ф)О
Authors: Маслюк Олена 
Published: October 2023

Сучасний викладач ‒ це професіонал, який не тільки науково та доступно викладає предмет, а й постійно розвиває себе й до цього спонукає здобувачів освіти. В статті дано характеристику дефініції «інформаційно-освітнє середовище»; висвітлено аспекти інформаційно-цифрової компетентності викладача; роль власного рівня цифрової компетентності викладача хімічних дисциплін в створенні інформаційного освітнього простору та сприятливих педагогічних умов спрямованих на підвищення якості освіти майбутніх медичних (фармацевтичних) фахівців.
ВПЛИВ ПРОГРАМ РУХОВОЇ РЕАБІЛІТАЦІЇ НА ЯКІСТЬ ЖИТТЯ У ПАЦІЄНТІВ З ХВОРОБОЮ ПАРКІНСОНА З ВИКОРИСТАННЯМ ФЕНОМЕНУ ПАРАДОКСАЛЬНОЇ КІНЕЗІЇ
Authors: Волошин-Гапонов Іван , Василовський Віталій , Богданова Ірина , Гапонов Петро 
Published: October 2023

Стаття присвячена дослідженню ефективності програми рухової реабілітації пацієнтів на хворобу Паркінсона (ХП) з використанням феномену парадоксальної кінезії (ПК) в умовах критичних форс-мажорних обставини (пандемії COVID-19 та війни).
Було обстежено 48 пацієнтів з ХП, які успішно реалізували програми рухової реабілітації з використанням феномену ПК на базі ДУ «Інститут неврології, психіатрії та наркології НАМН України».Одержані дані переконливо свідчать про те, що пацієнти з ХП, які успішно реалізували програми рухової реабілітації з використанням феномену ПК в он-лайн і оф-лайн режимах і продовжили виконання рекомендацій з регулярної рухової реабілітації, продемонстрували значуще вищі показники якості життя за всіма ключовими сферами.Таким чином, реалізація цих програм є ефективним засобом покращення стану психоемоційної сфери, а також покращення якості життя у хворих на ХП.
POLÍTICAS ECONÔMICAS RECENTES E AS CARACTERÍSTICAS DO MERCADO DE TRABALHO NA REGIÃO NORDESTE DO BRASIL
Authors: Mendonça Italo Do Nascimento , Neves Otávio Junio Faria , Batista Carolina Rocha 
Published: October 2023

O presente estudo buscou analisar as características recentes do mercado de trabalho da Região Nordeste do Brasil nos primeiros trimestres de 2019 e 2020. O processo metodológico foi realizado em duas etapas: uma análise descritiva de algumas taxas que caracterizam o mercado de trabalho nordestino no período mencionado; e, em segundo lugar, identificaram-se mudanças na composição do desemprego no Nordeste, de acordo com a metodologia de Corseuil et al (1997). Através da análise descritiva, verificou-se que todos os grupos analisados aumentaram sua taxa de desocupação nos trimestres analisados. Os indivíduos negros, mulheres, jovens e os trabalhadores com ensino fundamental e médio foram aqueles que mais sofreram pelos problemas do mercado de trabalho da região. Os fatores relacionados à demanda por trabalho foram os que mais tiveram impacto nesses indivíduos, quando se analisa a composição do desemprego nesse território. Como considerações finais, sugere-se que a Região Nordeste seja alvo de uma agenda de políticas que incentivem a demanda e que busquem a diminuição da desigualdade entre gêneros e que permita que os grupos mais fragilizados desse mercado de trabalho possam ser reinseridos em suas atividades econômicas e socias, desfrutando de uma vida digna já no curto prazo, finalizada a parte mais crítica da pandemia no Brasil.
The Hidden Economic Consequences of Migraine to the UK Government: Burden-of-Disease Analysis Using a Fiscal Framework
Authors: Martins Rui , Large Samuel , Russell Rachel , Surmay Gary , Connolly Mark P. 
Published: October 2023

Background: Migraine is a highly prevalent and incapacitating neurological disorder associated with the highest global disability burden in people aged 15 to 49 years. Europe has the fourth-highest prevalence of migraine, after North America, South America, and Central America, and above Asia and Africa. Migraine leads to relatively modest direct healthcare expenditure but has substantial indirect costs due to reduced productivity. Methods: The economic burden of migraine was estimated in comparison with the general population of the United Kingdom (UK) using an analytical fiscal modeling framework applying the government cost perspective. Published measures of migraine’s impact on labor participation were applied to rates of economic activity/inactivity of the general population. The model estimates lifetime changes to earnings from employment, direct and indirect taxes paid, and financial support requirements over the life course. Incremental differences between those affected and unaffected by migraine are reported as net fiscal consequences to public accounts. Fiscal costs are reported as the discounted average per capita over a 20-year time horizon and for the entire annual UK cohort with prevalent migraine. Results: People affected by migraine are more likely to be absent from work, unemployed, and disabled, and to retire early. A 44-year-old individual affected by migraine was associated with £19 823 in excess fiscal costs to the UK government, £1379 per year living with the condition, compared with someone not affected by the disease. Annually, migraine was estimated to represent £12.20 billion to the public economy, approximately £130.63 per migraine episode. The model predicted annual productivity losses in the health and social care workforce to be £2.05 billion and total annual productivity losses to be over £5.81 billion. Conclusions: This fiscal analysis monetizes the occupational consequences of migraine to the UK government, both in terms of lost tax revenue and transfer payments. The findings are substantial and useful to characterize disease severity and to inform the body of evidence considered by decision makers appraising the cost-effectiveness of health technologies.
Etiology of placental insufficiency in women in the second trimester of gestation during the epidemic of influenza A(H3N2) and pandemic influenza(H1N1)pdm
Authors: Gorikov I. N. , Reznik V. I. , Sergievich A. A. , Nakhamchen L. G. , Odireev A. N. , Prokopenko A. V. , Таrasyuk E. S. , Sudakov A. G. , Коlomiets O. E. , Gaidarova A. V. 
Published: October 2023

Aim. To study the etiology of placental insufficiency in women in the second trimester of gestation during the influenza A(H3N2) epidemic and the A(H1N1)pdm pandemic.Materials and methods. In 1865 patients in the second trimester of pregnancy, uncomplicated and complicated by exacerbation of chronic ENT pathology leading to the development of placental insufficiency, using laboratory methods in the blood, nasal epithelium and biological fluids, pathogens of monoand mixed infections (influenza A(H1N1)pdm), A(H3N2), influenza B, parainfluenza type 1-3, adenovirus, respiratory syncytial virus (RS), cytomegalovirus (CMV), herpes simplex virus type 1 and type 2 (HSV-1,2 type), candida infection (Candida albicans), chlamydia (Chlamydia trachomatis), mycoplasmosis (Mycoplasma hominis) and ureaplasmosis (Ureaplasma urealyticum) were detected. The first group consisted of 873 women with placental insufficiency diagnosed during the influenza A(H3N2) epidemic, the second group consisted of 890 patients with placental insufficiency diagnosed during circulation of the influenza A(H1N1)pdm in the population. The control group were 42 women without ENT diseases and placental insufficiency caused by monoand mixed viral infections during influenza A(H3N2) and 60 women with similar somatic, infectious and obstetric status, examined during pandemic influenza A(H1N1)pdm.Results. With the development of placental insufficiency in women of the second group, compared with the first one, mono-influenza B and parainfluenza types 1-3 are diagnosed less frequently, as well as a combination of influenza A(H1N1) pdm and influenza B; influenza A(H1N1)pdm and parainfluenza types 1-3; influenza A(H1N1)pdm and RS virus; CMV and Chlamydia trachomatis; Mycoplasma hominis and Ureaplasma urealyticum; HSV-1,2 type, Candida albicans and Chlamydia trachomatis; as well as HSV-1,2 type, Candida albicans and Ureaplasma urealyticum. At the same time, exacerbations of mono-CMV, mono-HSV-1,2 type and Candida albicans are more common, as well as combinations of CMV+HSV-1,2 type; CMV+Candida albicans; CMV+Ureaplasma urealyticum; and CMV+Mycoplasma hominis; CMV+HSV-1,2 type+Candida albicans.Conclusion. In the etiology of placental insufficiency in acute diseases of the ENT organs in women in the second trimester of gestation against the background of circulation of the A(H1N1)pdm influenza in the population, compared with placental dysfunction in pregnant women with a similar ENT pathology during the influenza A(H3N2) epidemic, there is an increase in the proportion of monocytomegalovirus, herpesvirus and candida infections, as well as mixed cytomegalovirus infection, the reactivation of which may be due to more pronounced virusinduced immunosuppression and hormonal status disorders, leading to local dysbiosis.
Clinical observation of small cell neuroendocrine cancer of the tracheal bifurcation zone, with metastasis to the bone marrow, liver, spleen
Authors: Voitsekhovskiy V. V. , Grigorenko A. A. , Esenina T. V. , Roshchin S. N. , Filatova E. A. , Fedorova N. A. , Astasheva T. A. , Solovieva M. I. , Tuboltseva N. V. 
Published: October 2023

Aim. Demonstration of a clinical case of a patient with small cell neuroendocrine cancer of the tracheal bifurcation zone, with metastases to the bone marrow, liver, spleen.Materials and methods. A brief review of the literature on the diagnosis of neuroendocrine tumors of the lungs and bronchi is presented, and a clinical observation of small cell neuroendocrine cancer of the tracheal bifurcation zone with metastases to the bone marrow, liver and spleen from the personal practice of the authors is presented.Results. The clinical picture of this patient was dominated by “hematological” manifestations: severe thrombocytopenia and hemorrhagic syndrome, anemia, due to which differential diagnosis with a systemic blood disease was initially carried out. There was no pain syndrome in the bones characteristic of metastatic lesions. Histological examination of the bronchial tumor biopsy and bone marrow trephine biopsy with immunohistochemical examination (IHC) helped in making the diagnosis. In both cases, IHC revealed tumor cells with the same phenotype.Conclusion. Metastasis of tumors to the bone marrow can proceed without characteristic ossalgia and manifest itself only in hematological syndromes (changes in blood tests). Cytological and histological examination of the bone marrow, with IHC, helps in the diagnosis.
Contact methods for registering respiratory rate: opportunities and perspectives
Authors: Garanin A. A. , Rubanenko A. O. , Shipunov I. D. , Rogova V. S. 
Published: October 2023

Introduction. Respiratory rate is known to be one of the most important indicators reflecting the vital functions of a person. An increase in respiratory rate can be found in many diseases and pathological conditions, for example, in chronic obstructive pulmonary disease, pneumonia, bronchial asthma, myocardial infarction, heart failure, anaemia, etc. Due to the active introduction of telemedicine monitoring into clinical practice, the measurement of the abovementioned indicator is particularly relevant for the purpose of early detection and prevention of complications of chronic non-infectious diseases, as well as dynamic monitoring of the condition of patients in both inpatient and outpatient settings.Aim. To search and update information about existing and promising developments for the control of respiratory rate based on different physical principles.Materials and methods. For this review we used databases PubMed, Scopus, MedLine and eLIBRARY. The following keywords were used for the search: “respiratory rate”, “contact”, “measurement”, “sensor”.Results. Contact methods for measuring respiratory rate include a wide range of sensors based on various physical principles. All types of sensors have their own application, but also they have some drawbacks. In order to achieve maximum accuracy of respiratory rate monitoring, it is necessary to carefully assess the conditions in which the patient is located, selecting the most appropriate technological solutions for them. Probably, complex systems, including several different sensors, are able to overcome many shortcomings. In addition, the development of information analysis methods, machine learning and artificial intelligence technologies can increase the sensitivity and accuracy of methods of measuring respiratory rate, reducing the frequency of bias associated with various artefacts.Conclusion. Thus, technological development opens up wide opportunities for long-term monitoring of vital functions, prevention and timely response to adverse events.
The state of mitochondrial membrane potential in peripheral blood leukocytes of patients with chronic obstructive pulmonary disease
Authors: Sugaylo I. Yu. , Gassan D. A. , Naumov D. E. , Kotova O. O. , Gorchakova Y. G. , Sheludko E. G. 
Published: October 2023

Introduction. Mitochondria provide energy homeostasis of the cell by maintaining an optimal transmembrane electrochemical gradient (ΔΨm), which does not allow excessive formation of reactive oxygen species (ROS). However, under conditions of pathology, the normal functioning of mitochondria is disrupted, which can lead to ATP deficiency and/or increased production of ROS.Aim. The aim of this study was to investigate the ΔΨm parameters and their relationship with the expression of TRP channels in peripheral blood leukocytes of patients with chronic obstructive pulmonary disease (COPD).Materials and methods. The study included 23 patients with COPD of varying severity, 8 smokers without signs of bronchial obstruction and 9 healthy volunteers who had never smoked. All subjects underwent spirometry to assess the lung function. ΔΨm was determined by staining the cells with tetramethylrhodamine ethyl ester (TMRE) and measuring the fluorescent signal by flow cytometry, under basal conditions and pro-inflammatory stimulation with phorbol-12-myristate-13-acetate (PMA).Results. We found that COPD patients were characterized by a significant increase in basal ΔΨm of monocytes (161.8 [153.8; 206.8] vs. 129.3 [75.5; 161.8], p=0.03) and lymphocytes (209,7 [184.7; 257.8] vs. 122.5 [67.9; 164.3], p=0.003) as compared with the control group. Stimulation of cells with PMA led to multidirectional changes in ΔΨm, while its increased level was still preserved in COPD. In monocytes of COPD patients, a decrease in ΔΨm in response to PMA stimulation was prevalent (75%), while in the majority (53.9%) of individuals in the control group ΔΨm, on the contrary, increased (p=0.08). In addition, among COPD patients, an increase in ΔΨm in monocytes was accompanied by an enhanced expression of TRPV4, while in the control group, among individuals with positive dynamics of ΔΨm, TRPV4 expression was, on the contrary, reduced.Conclusion. The increased level of ΔΨm in the mononuclears of COPD patients is consistent with previously detected enhanced ROS production, but does not support the assumption about energy deficit in the cells. The revealed differences in the relationship between TRPV4 expression and ΔΨm dynamics may indicate the presence of pathological features in TRP signaling in COPD patients.
Bronchopulmonary dysplasia in children of the Amur region: the structure of the disease
Authors: Suprun S. V. , Abdulina N. O. , Pichugina S. V. , Sorvina T. A. , Evseeva G. P. , Lebedko O. A. 
Published: October 2023

Aim. Analysis of the structure of bronchopulmonary dysplasia (BPD) in children of the Amur region at the stage of medical care in outpatient and inpatient conditions of the Research Institute of MCP for the period from 20102021.Materials and methods. The study used a retrospective analysis of outpatient records and medical histories of 146 patients with BPD aged from 1 month to 13 years.Results. Among children with BPD, boys accounted for 56.6%, girls 44.3%. Preterm infants accounted for 84.9%, full-term babies – 15.1%. The classic form of the disease was diagnosed in 56% of children, the new form – in 44%. Since 2013, there has been a decrease in the frequency of occurrence of the classical form (in 2011 – 100%, in 2021 – 0%). The opposite pattern is typical for the new form (in 2010 – 14.3%, in 2021 − 100%). Since 2018, there has been a tendency for the new form to prevail over the classical form. Concomitant pathology of the respiratory system was diagnosed in 40.2% of patients (5.03% of them were malformations, stridor – 33.3%, their combination – 1.9%), and pathology of the cardiovascular system in 3.8% of cases.Conclusion. The assessment and dynamics of the structure of BPD disease in the Amur region at the present stage is presented. We report the predominance of a new form of BPD over the classical one. The study noted the frequency of concomitant pathology on the part of the respiratory and circulatory systems in children with BPD. The identified features will be used to search for risk factors for the development and prognosis of this pathology.