bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association Between Prosuicide Website Searches Through Google and Suicide Death in the United States From 2010 to 2021: Lagged Time-Series Analysis (Preprint)
Authors: Kelsall Nora Clancy , Gimbrone Catherine , Olfson Mark , Gould Madelyn S , Shaman Jeffrey , Keyes Katherine 
Published: October 2023

BACKGROUND

The rate of suicide death has been increasing, making understanding risk factors of growing importance. While exposure to explicit suicide-related media, such as description of means in news reports or sensationalized fictional portrayal, is known to increase population suicide rates, it is not known whether prosuicide website forums, which often promote or facilitate information about fatal suicide means, are related to change in suicide deaths overall or by specific means.

OBJECTIVE

This study aimed to estimate the association of the frequency of Google searches of known prosuicide web forums and content with death by suicide over time in the United States, by age, sex, and means of death.

METHODS

National monthly Google search data for names of common prosuicide websites between January 2010 and December 2021 were extracted from Google Health Trends API (application programming interface). Suicide deaths were identified using the CDC (Centers for Disease Control and Prevention) National Vital Statistics System (NVSS), and 3 primary means of death were identified (poisoning, suffocation, and firearm). Distributed lag nonlinear models (DLNMs) were then used to estimate the lagged association between the number of Google searches on suicide mortality, stratified by age, sex, and means, and adjusted for month. Sensitivity analyses, including using autoregressive integrated moving average (ARIMA) modeling approaches, were also conducted.

RESULTS

Months in the United States in which search rates for prosuicide websites increased had more documented deaths by intentional poisoning and suffocation among both adolescents and adults. For example, the risk of poisoning suicide among youth and young adults (age 10-24 years) was 1.79 (95% CI 1.06-3.03) times higher in months with 22 searches per 10 million as compared to 0 searches. The risk of poisoning suicide among adults aged 25-64 was 1.10 (95% CI 1.03-1.16) times higher 1 month after searches reached 9 per 10 million compared with 0 searches. We also observed that increased search rates were associated with fewer youth suicide deaths by firearms with a 3-month time lag for adolescents. These models were robust to sensitivity tests.

CONCLUSIONS

Although more analysis is needed, the findings are suggestive of an association between increased prosuicide website access and increased suicide deaths, specifically deaths by poisoning and suffocation. These findings emphasize the need to further investigate sites containing potentially dangerous information and their associations with deaths by suicide, as they may affect vulnerable individuals.

CLINICALTRIAL
OPTICAL PROPERTIES OF Ag7SiS5I AND Ag7GeS5I SINGLE CRYSTALS
Authors: Shender I.O. , Pogodin A.I. , Filep M.J. , Malakhovska Т.О. , Pop M.M. , Kokhan O.P. , Suslikov L.M. 
Published: October 2023

Compounds with a disordered structure attract significant scientific interest, since structural disorder directly affects the properties of the material. This paper presents a study of the optical properties of Ag7SiS5I and Ag7GeS5I single crystal, which are related to compounds with the structure of argyrodite. Single crystals of quaternary Ag7SiS5I and Ag7GeS5I were grown by the method of directed crystallization from the melt. Investigation of grown single crystals by the XRD method indicates that both compounds crystallize in SG F-43m. The optical properties were studied at room temperature (20°C) in the spectral range of 200–1100 nm. The beginning of the optical transmission region is observed at λ = 790 nm and λ = 860 nm for Ag7SiS5I to Ag7GeS5I, respectively. It was established that Ag7GeS5I single crystals have a higher bandwidth compared to Ag7SiS5I. When transitioning from Ag7SiS5I to Ag7GeS5I, a shift of the transmission region to a longer wavelength region is observed. The energies of direct allowed and forbidden optical transitions in Ag7SiS5I and Ag7GeS5I single crystals were determined using the Tauc equation. It was established that the corresponding energies values are higher in the case of the Ag7SiS5I single crystal for both considered optical transitions.
Keywords: argyrodites; single crystals; optical spectroscopy; optical transitions.
POTENTIOMETRY IN DETERMINING THE CONDITIONS FOR THE FORMATION OF TETRAFLUORBORATE AS AN ANALYTICAL FORM OF BORON
Authors: Fershal M.V. , Studenyak Ya. I. 
Published: October 2023

The present paper deals with the research on the optimal conditions for the formation of fluoroborate as an analytical form of boron. Despite numerous scientific publications related to the determination of boron using various methods involving [BF4]ˉ ions as an analytical form, the conditions for obtaining the latter differ significantly. This difference is likely due to the complexity of the H3BO3-F--H3O+ system, where polymolecular forms of hydrofluoric acid can exist. Factors such as the inability to measure pH using a glass electrode, the velocity of the complexation process, and the requirement for specialized labware and equipment resistant to aggressive environments contribute to this complexity. In this study, potentiometry with PVC plasticized [BF4]ˉ - sensors, known for their metrological and operational characteristics, was used as a convenient tool to investigate such systems. The [BF4]ˉ - selective electrode based on the electroactive substance ion pair 2-(N-ethylcarbazole-3)-ethenyl-1,3,3-trimethyl-3H-indole tetrafluoroborate, which retains its metrological characteristics in acidic and strongly acidic environments and exhibits selectivity up to F-(= -4. 0), was employed as a sensor.
The sensor allowed for the study of [BF4]ˉ - complex formation under different reaction conditions by recording kinetic curves in EMF-time coordinates. The yield of the analytical form was estimated at different concentrations of acid, fluoride ions, and temperature. The obtained data were used to construct the yield surface of tetrafluoroborate, revealing that the optimal conditions for the formation and stability of tetrafluoroborate at room temperature are a medium of 1 M sulfuric acid and 0. 25 M NH4F. Under these conditions, the yield of [BF4]ˉ reaches 99% within 10 minutes. Although the use of phosphoric acid does not allow for the attainment of an appropriate yield of the analytical form under equilibrium conditions, its low process velocity makes it suitable for kinetic - potentiometric determination of boron. This characteristic was utilized to develop a method for the determination of boron in phosphoric acid using the fixed-time method.
Keywords: tetrafluoroborate ion; potentiometric sensor; kinetic determination of boron.
SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SELENO(MERCURY)HALOGEN-CONTAINING BENZOTHIAZOLE DERIVATIVES
Authors: Haleha O.V. , Povidaichyk M.V. , Komarovska-Porokhnyavets O.Z. , Onysko M.Yu. , Sukharev S.М. 
Published: October 2023

Derivatives of benzothiazole are sufficiently well researched as substrates for obtaining a number of condensed and hybrid polycyclic heterocycles that exhibit various biological activities, namely, they exhibit anticancer, antimicrobial, antioxidant activity, can be used as antidiabetic agents, analgesics, and inhibitors of viral infections. In this work, the possibility of seleno- and mercury-induced cyclization of 2-cinnamylthiobenzothiazole and the prospect of the usage of seleno- and mercury-containing benzothiazole derivatives as bactericidal and fungicidal agents are investigated. It was established that non-regioselective selenium-induced cyclization of 2-cinnamylbenzothiazole occurs during the reaction of 2-cinnamylthiobenzothiazole with the mixture of selenium dioxide and hydrobromic acid in a chloroform medium; reaction leads to the formation of a mixture of selenium-containing regioisomers of 4-phenyl-3-(tribromo-l4-selanyl)-3,4-dihydro-2H-[1,3]thiazino[2,3-b][1,3]benzothiazolium bromide and 4,4-dibromo-3-[bromo(phenyl)methyl]-3,4-dihydro-2H-4l4-[1,4,3]thiaselenazino[2,3-b][1,3]benzothiazolium bromide. On the other hand, a molecular complex is formed in a ratio of 1:1, when mercuriating of 2-cinnamylthiobenzothiazole with mercury chloride,. Experimentally determined fungicidal properties of seleno-, mercury-, and tellurium-containing derivatives of benzothiazole indicate the prospect of their use as bactericidal and antifungal agents
Keywords: 2-cinnamylthiobenzothiazole; thiazino[2,3-b][1,3]benzothiazolium, thiaselenazino[2,3-b][1,3]benzothiazolium, molecular complex, fungicidal activity.
INFLUENCE OF ASSESSMENT METHODS ON INTERMEDIATE RESULTS OF MEDICAL STUDENTS
Authors: Korol N. , Kut M. , Lendel V. , Slivka M. , Onysko M. , Kryvovyaz A. , Rusyn I. , Faryniuk Yu. 
Published: October 2023

The conducted research revealed that first-year students of the medical faculty prefer distance learning and the use of multiple-choice testing on an electronic educational platform when studying the course "Bioorganic Chemistry." Meanwhile, traditional classroom sessions without visual aids and open-ended questions showed the lowest performance indicators. However, students mentioned that they most effectively assimilate the educational material during such sessions, while also acknowledging the positive impact of quality visual aids on comprehension. Based on the obtained results, it is recommended to continue developing a question bank and utilizing the electronic educational platform with multiple-choice testing, but with modifications to the tasks and variations in test parameters. The research indicates that students perceive the use of technology and interactive teaching methods positively, which provide a more flexible learning environment and the opportunity for independent study. The research findings can be valuable in curriculum development and improving the quality of the educational process. Furthermore, it is worth considering the possibility of implementing a wider range of interactive teaching methods and utilizing modern technologies that foster active student engagement in the learning process.
Keywords: quality of education; academic success; testing; form of education.
THE POSSIBILITY OF EFFECTIVE USE OF BASIC DYES OF THE "BAZAKRYL" TRADEMARK IN THE DETERMINATION OF ANIONIC SURFACTANTS
Authors: Rusyn V.M. 
Published: October 2023

This study shows the prospects of using "Bazacryl" brand dyes in spectrophotometric analysis. On the basis of previous studies, their main spectrophotometric and protolytic characteristics have already been established, which made it possible to find out the optimal conditions for the formation of ionic associates of anionic surfactants with "Bazakrils". The studied dyes are characterized by a sufficiently high color intensity within a wide range of changes in the acidity of the medium, and in terms of these properties, they are not inferior to the majority of known basic dyes used in analytical practice. The kinetic factors of extraction were studied. As a result, the extraction equilibrium is established after 10-30 seconds of mixing the phases and practically does not depend on the used extractant, but 1-3 min. centrifugation is sufficient for complete phase separation. The optical density of the extracts of the formed IA does not change within 2 hours. It was established that such dyes show the ability to form IA from APAR and can serve as analytical reagents for their determination. The optimal conditions for the formation and extraction of IA APAR with new dyes have been established. A new, simple and rapid method for determining APAR in various samples of wastewater and natural waters, detergents, etc. is proposed.
Keywords: dyes; spectrophotometry; ionic associate; protolytic properties; spectrophotometric properties.
Una caja de pandora por el río
Authors: Sturla Natalio 
Published: October 2023

Reseña a Marcia Müller y Juan Pedro Zubieta (2023). Acordeón con alma de Chamamé. Ediciones Moglia, 302 páginas.
El acordeón diatónico, fundamental en la conformación del género chamamé, presenta escasas investigaciones y publicaciones que den cuenta de cómo y por qué llegó a ser reconocido como el portador del sonido de la región del Litoral. Marcia Müller y Juan Pedro Zubieta plantean en este libro un recorrido histórico desde su origen, el proceso de «acordeonización» de los ritmos litoraleños, y la manera en que las modificaciones en la mecánica de su funcionamiento incidieron en la configuración musical de las obras.
Performance studies on hybrid nano-metal matrix composites for wear and surface quality
Authors: Kannan P.R. , Thanigaivelan R , Thiraviam R , Pradeep Kumar K 
Published: October 2023

Abstract
Aluminium-based hybrid nano-metal matrix composites are right materials, finding application in the aerospace and automotive industry. The present research focused on the effects of sliding load, sliding velocity, and temperature on wear behaviour of a novel hybrid metal matrix nano-composite .Stir-squeeze casting setup is used to produce the composites. The base metal is scrap aluminium alloy wheel (SAAW) reinforced with 1, 2, wt.% and 5.5, 7 wt.% of micro-sized alumina (Al2O3)m and nano-sized alumina (Al2O3)n particle respectively. An orthogonal array L9 (OA) has been used for designing the experiments. Technique for Order Preference by Similarity to Ideal Solution (TOPSIS) is applied to find the optimal condition for Coefficient of Friction(COF),wear, surface roughness. Analysis of Variance (ANOVA) results show that the reinforcement contributes 19.40% and most influencing factor is sliding load with 62.33%. The samples tested were examined and analyzed using a Field Emission Scanning Electron Microscope (FESEM) and an energy-dispersive X-ray spectrometry (EDX). Additionally, a profilometer was used to measure the surface roughness of the worn-out specimen.
Domestic Investment and Economic Growth Nexus: Does Absorptive Capacity Matter in The African Countries?
Authors: Ogunyomi-Oluyomi Oluwatosin Olatunji , George Emmanuel Oladapo , Maku Olukayode Emmanuel , Adelowokan Oluwaseyi A. 
Published: October 2023

Abstract
This study empirically examined the role of the country’s absorptive capacity on the impact of domestic investment on economic growth in the selected five African countries over the study period of 1970 to 2019. In specific, the study examined the impact of domestic investment on economic growth from two models, without the country’s absorptive capacity and with the country’s absorptive capacity. Further, a robust linear ordinary least squares (OLS) methodology including static panel OLS and panel cointegration estimators was employed. The study found that only changes in financial development and infrastructures positively cause changes in the domestic investment-economic growth nexus in the short run while in the long run, trade openness enhances the positive impact of domestic investment on economic growth in African countries. In addition, the study found that domestic investment retards economic growth without the country’s absorptive capacity in the short run and long run respectively in African countries. Therefore, the study recommended that policymakers should invest heavily in infrastructure and financial development systems as well as encourages trade openness for a stable domestic investment-economic growth nexus in African countries.
Transformations of the Landscape and Territory of Chapada Diamantina Through the Insertion of the Central Pivot as Irrigation
Authors: Lima Espedito Maia , Rocha Altemar Amaral , Figueredo Dhione Andrade , Meira Vandique Martiniano Campos , Veiga Adriana Cruz 
Published: October 2023

Objective: This research analyzes the changes in landscapes and territory in Chapada Diamantina, with emphasis on the municipalities of Ibicoara-BA and Mucugê-BA, caused by the implementation of central pivot irrigation systems and the appropriation of these spaces by agribusiness.

Theoretical framework: This study was conducted based on theoretical reflections on environmental issues, the relationship between society and nature and theories on space and territory. Water use issues, granting policies and the procedures that bodies in the environmental sector used to monitor access to water and its multiple uses.

Method: It is based on the use of data collection with thematic mapping, use of satellite images and theoretical discussion. The data were obtained from the Brazilian Institute of Geography and Statistics (IBGE), the National Water Agency (ANA), the Brazilian Agricultural Company - Embrapa and the Institute of the Environment and Water Resources (INEMA).

Results and conclusion: The results demonstrate strong growth in agribusiness in Chapada Diamantina and a high impact on environmental resources, especially due to the removal of vegetation cover from the surfaces of Gerais and an increase in demand for water.

Implications of the research: The environmental and territorial approach of the research questions the development model implemented in the region, pointing out intra-regional inequalities, and the environmental problems arising from the massive land and water in the area with high environmental fragility.

Originality/value: This research has social, economic, scientific and environmental value with the data analyzed and the originality of the discussions presented.
West Nile virus in the Iberian Peninsula: using equine cases to identify high-risk areas for humans
Authors: García-Carrasco José-María , Muñoz Antonio-Román , Olivero Jesús , Segura Marina , García-Bocanegra Ignacio , Real Raimundo 
Published: October 2023

BackgroundWest Nile virus (WNV) is a flavivirus with an enzootic cycle between birds and mosquitoes; humans and horses are incidental dead-end hosts. In 2020, the largest outbreak of West Nile virus infection in the Iberian Peninsula occurred, with 141 clusters in horses and 77 human cases.AimWe analysed which drivers influence spillover from the cycle to humans and equines and identified areas at risk for WNV transmission.MethodsBased on data on WNV cases in horses and humans in 2020 in Portugal and Spain, we developed logistic regression models using environmental and anthropic variables to highlight risk areas. Models were adapted to a high-resolution risk map.ResultsCases of WNV in horses could be used as indicators of viral activity and thus predict cases in humans. The risk map of horses was able to define high-risk areas for previous cases in humans and equines in Portugal and Spain, as well as predict human and horse cases in the transmission seasons of 2021 and 2022. We found that the spatial patterns of the favourable areas for outbreaks correspond to the main hydrographic basins of the Iberian Peninsula, jointly affecting Portugal and Spain.ConclusionA risk map highlighting the risk areas for potential future cases could be cost-effective as a means of promoting preventive measures to decrease incidence of WNV infection in Europe, based on a One Health surveillance approach.
Pituitary adenoma: literature review and association with TAS2R16 (rs978739, rs1357949) gene polymorphisms
Authors: Pileckaitė E. , Gedvilaitė G. , Kriaučiūnienė L. 
Published: October 2023

The pituitary gland is the primary regulatory gland in the endocrine system transmitting signals from the hypothalamus to target organs through hormone release. Through the release of hormones, the pituitary gland regulates vital physiological functions: growth, reproduction, metabolism, and the stress response. Disorders in the pituitary gland can cause damage, such as pituitary adenomas (PA). PA is the most common benign tumor arising from epithelial cells of the anterior pituitary gland. PA is one of the most common tumors of the central nervous system. PA is differentiated by hormone secretion into non-secretory (non- functional) and secretory (functionally active). Excess hormones secreted by PA can cause clinical syndromes, such as hyperprolactinemia (caused by excessive secretion of prolactin), acromegaly (due to excess growth hormone), and Cushing’s syndrome (due to excessive production of the adrenocorticotropic hormone ACTH)). Studies show that the prevalence of adenomas in the population is approximately 80/100,000. The occurrence of PA is influenced not only by somatic or germ cell defects but also by environmental factors. The exact cause of PA is still unclear, but it is known that a small part (~5%) of PA due to hereditary syndromes is caused by gene changes. Considering the influence of environmental factors and genetic alterations that affect the occurrence of PA, new genetic markers can be searched to detect this disease. One of the risk factors contributing to the development of PA and its aggressiveness is alcohol consumption. Excessive alcohol consumption affects not only the development of PA but also the manifestation of other cancers. A recent study has investigated the association of TAS2R16 gene single nucleotide polymorphisms (SNPs) with colon cancer, as SNPs in this gene have been found to increase alcohol dependence. Based on the association of TAS2R16 SNPs with cancer, we decided to investigate the association of TAS2R16 gene (rs978739, rs1357949) polymorphisms with PA.
ESTÁNDARES JURISPRUDENCIALES DE LA PRESCRIPCIÓN EXTRAORDINARIA DE DOMINIO EN LA REALIDAD ECUATORIANA.
Authors: Martínez Rommel 
Published: October 2023

La presente investigación desarrolla el ámbito legal, sobre la prescripción extraordinaria de dominio en Ecuador, se plantea desafíos debido a la influencia de la jurisprudencia en la interpretación y aplicación. La jurisprudencia, como fuente formal del Derecho, es crucial para determinar cómo se interpreta y aplica una norma, pero en ocasiones puede ir más allá de una interpretación literal y generar incertidumbre o interpretaciones variadas sobre la prescripción extraordinaria. Es esencial equilibrar la evolución de la jurisprudencia con la consistencia y previsibilidad en la aplicación del Derecho, buscando estándares claros y coherentes basados en principios sólidos. La eficacia y justicia de la prescripción extraordinaria de dominio dependen de cómo se interprete y aplique, por lo que se requiere un análisis cuidadoso y una reflexión continua para garantizar un sistema legal justo y predecible. El objetivo de la investigación es determinar por medio de la jurisprudencia vinculante en todos sus niveles cuales son los requisitos indispensables para que se configure la prescripción extraordinaria de dominio, a fin de identificar la interpretación que los administradores de justicia realizan en cuanto a la aplicación de la normativa y la jurisprudencia. La metodología empleada en este estudio se enmarca en una investigación teórico-descriptiva de tipo documental. Se llego a la conclusión de que, la jurisprudencia desarrolla estándares aplicables como identificación de bienes prescriptibles, determinación y singularización de los bienes, el tiempo en el que se perfecciona la figura jurídica y la posesión vista desde el desarrollo jurisprudencial.
Palabras claves: prescripción extraordinaria de dominio, bienes prescriptibles, seguridad jurídica, animo de señor y dueño.