bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced wound recovery after surgery care in patients with total knee arthroplasty: A meta‐analysis
Authors: Wang Lifeng , Lin Zhijin 
Published: February 2024

AbstractThis study primarily focussed on the impact of Enhanced Recovery After Surgery (ERAS) care on wound healing and pain management in patients undergoing total knee arthroplasty (TKA). TKA is the critical surgical intervention aimed at improving the quality of life in patients with knee osteoarthritis. While this procedure has been effective in enhancing mobility and life quality, postoperative phase, particularly wound healing, remains significant concern. This research aimed to evaluate the effectiveness of ERAS care protocols in promoting wound healing and reducing postoperative wound pain. A comprehensive literature review was conducted to identify studies focusing on wound healing and pain management in TKA patients under ERAS care. The systematic search employed various terms related to TKA, wound healing and ERAS. During the screening process, data relevant to wound healing outcomes were prioritized for inclusion in the meta‐analysis. Using the R package ‘meta’, meta‐analysis was performed on a sample of 664 patients, divided into 349 in the intervention group (ERAS care) and 315 in the control. The results indicated significant enhancement in wound healing and reduction in postoperative wound pain among patients receiving ERAS care (risk ratio [RR] = 1.12, 95% confidence interval [CI]: 0.9152; 1.3929, p < 0.01). Additionally, pain score analysis across the studies revealed that the ERAS group consistently experienced less wound pain postoperatively compared with the control, with average of 0.1 point difference in pain scores indicating significantly less pain. Conclusively, our findings underscored the importance of implementing structured ERAS care protocols in TKA procedures. These protocols not only alleviated postoperative wound pain but also promoted effective wound healing, thereby potentially enhancing overall recovery and surgical outcomes for patients with knee osteoarthritis undergoing TKA.
Etiological characteristics of wound infection in severe trauma patients and logistic regression analysis of influencing factors of infection
Authors: Pan Xiaocui , Mo Ling , He Xiuping 
Published: February 2024

AbstractTo investigate the etiological characteristics of wound infection in severe trauma patients and logistic regression analysis of the influencing factors of infection. The 116 patients with severe trauma who were intervened in our hospital from 22 October 2017 to 9 September 2019 were selected as the subjects of this retrospective study and divided into a control group and an observation group according to whether they were infected or not, 58 cases each. Observe and compare the pathogenic characteristics (pathogen distribution and drug resistance) of the two groups of patients and logistic regression analysis of the influencing factors of infection. The gram‐positive bacteria in the observation group were mainly Staphylococcus aureus, accounting for 17.20%; the fungi were mainly Candida tropicalis, accounting for 17.20%; and the gram‐negative bacteria were mainly Acinetobacter baumannii, accounting for 20.39%; the control group was gram‐positive. The main bacteria are S. aureus, accounting for 8.60%; the fungi are mainly Candida albicans, accounting for 4.3%; and the gram‐negative bacteria, which are mainly Pseudomonas aeruginosa, accounting for 14.56%. Gram‐positive bacteria Enterococcus faecium, S. aureus, Enterococcus faecalis, Staphylococcus epidermidis. The highest drug resistance of other gram‐positive bacteria is penicillin and erythromycin at 85.00% and above. Fungi C. tropicalis, Candida parapsilosis, C. albicans, fluconazole and amphotericin B have the highest resistance to 80.00% and above. Gram‐negative bacteria A. baumannii, Ps. aeruginosa, Klebsiella pneumoniae, Escherichia coli, Proteus mirabilis, Enterobacter cloacae and other gram‐negative bacteria are the most resistant to ampicillin, and Piperacillin was 70.00% and above. The combined primary diseases of the two groups of patients, ventilator use ≧3 days, long‐term use of glucocorticoids, catheter use days ≧5 days, fever days ≧3 days and long‐term use of broad‐spectrum antimicrobial drugs, the difference is statistically significant academic significance (p < 0.05). Logistic analysis showed that combined with underlying diseases, fever days ≥3 days, long‐term use of glucocorticoids and catheter use days ≥5 days are the influencing factors for the occurrence of wound infections in patients with severe trauma. Trauma patients are prone to wound infections, and there are many influencing factors. Close observation of patients should be strengthened. Effective prevention and control measures should be taken for related influencing factors to reduce the incidence of infection.
A meta‐analysis of clinical studies of moxibustion for pressure ulcer healing
Authors: Yu Wangling , Shi Beiyin , He Qingqing , Zhang Shuyi 
Published: February 2024

AbstractIn this study, we aimed to evaluate the effect of moxibustion on pressure ulcers. A thorough search was performed for articles published from database inception up to 14 December 2023. Randomized controlled trials, which evaluated the effects of moxibustion were included. Finally, 11 relevant trails that enrolled a total of 795 participants met inclusion criteria. The results of meta‐analysis suggested beneficial effects of moxibustion for pressure ulcer compared with control on the response rate (RR: 1.21; 95% CI: 1.13–1.29; p = 0.82; I2 = 0%), healing time (MD: −5.69; 95% CI: −9.58 to −1.80; p<0.05; I2 = 97%) and pressure ulcer scale for healing scores (MD: −1.13; 95% CI: −1.36 to −0.89; p = 0.79; I2 = 0%). The evidence suggests that moxibustion possesses satisfactory efficacy in promoting healing of pressure ulcers. However, due to the small number of trials included in this study, as well as the small sample size and high risk of bias, we were unable to draw firm conclusions about the effectiveness of moxibustion for pressure ulcers.
Examining cognitive accessibility of the VIA Inventory of Strengths for adults with intellectual disability
Authors: Greenberg Kimberly , Hounshel Brice , Kalb Luke , Schwartz Ariel 
Published: February 2024

AbstractBackgroundWe evaluated cognitive accessibility of the VIA Inventory of Strengths Youth short form with adults with intellectual disability for use in strengths‐based practice.MethodsWe conducted cognitive testing with adults with intellectual disability (n = 33; M age = 36.2; range: 20.4–64.2). Data were coded for the extent to which (1) items were interpreted correctly; (2) participants endorsed items as describing themselves. We calculated descriptive statistics to evaluate item interpretation and response scale use.ResultsOn average, 59% of participants interpreted items correctly, 20% misinterpreted items, 14% had mixed interpretations. Positive item endorsement was most associated with the response ‘Very much like me’ (77%); mixed endorsement was most associated with ‘Somewhat like me’ (39%); and negative endorsement of items was most associated with ‘Not at all like me’ (54%).ConclusionsRevisions are necessary for several items to improve accessibility for adults with intellectual disability and should be made in collaboration with this population.
Functions of the sulfatase‐modifying factor 1 (HaSumf1) in the development and host glucosinolate adaptation of Helicoverpa armigera
Authors: Zhang Long , Zhou Zhiran , Cai Fan , Qin Wanli , Liu Li , Kuerban Guli , Jin Lin , Ma Xiaoli 
Published: February 2024

AbstractThe system of gulcosinoalte sulfatase–sulfatase‐modifying factors (Sumfs) in herbivorous insects fulfils an essential function in defending host plant glucosinolates (GLSs)—the compounds of cruciferous plants—by swiftly desulfurising them. Previously, eight HaSulfs and one HaSumf1 were identified in Helicoverpa armigera. GLSs have a significant impact on the growth and development of H. armigera larvae. They can induce the expression of HaSulf in the midgut of H. armigera at both gene and protein levels. In the present study, we utilised RNAi technology to silence the HaSumf1 gene and explored its potential impact on the growth, development, and adaptation of GLSs. The sequence analysis has indicated that the HaSumf1 gene in H. armigera shares a high degree of sequence identity with other insect genes and is expressed at its highest level in the fifth‐instar phase. Additionally, the qRT‐PCR results reveal that the expression of HaSumf1 was upregulated by 1.26 and 0.07 times in third‐instar and 1.65 and 0.19 times in fifth‐instar when fed with 0.004% and 0.04% GLS, respectively. The effectiveness of dsSumf1 silencing was observed in both third‐ and fifth‐instar stages, with silencing rates of 65.5%–88.9% and 61.3%–74.6%, respectively (p < 0.05). The findings of the bioassay indicate that H. armigera's body weight at fifth‐instar significantly increased after treatment with 0.004% GLS and 0.04% GLS, while the larval survival rate, pupation rate, and pupa weight decreased. Notably, when feeding dsRNA‐encapsulated carbon quantum dots (CQD‐dsRNA), this trend was significantly strengthened (p < 0.05). Taken together, these findings provide evidence supporting HaSumf1's conservation involvement in the adaptation of host plant GLSs during lepidopteran insect evolution. Therefore, it plays a critical role in the growth and development of H. armigera, offering molecular targets for developing novel pesticides and targeted control measures against this vital pest.
An equatorial mid‐Atlantic Ocean archipelago as nursery area for the cookiecutter shark: Investigating foraging strategies of neonates through bite mark inferences
Authors: Santos Lucas , Veloso João V. , Santos Theresa B. , Bezerra Natalia P. A. , Oliveira Paulo , Hazin Fabio H. V. 
Published: February 2024

AbstractThis study delves into the foraging ecology of the cookiecutter shark (Isistius brasiliensis) in the Saint Peter and Saint Paul Archipelago (SPSPA), assessing bite marks on pelagic fishes collected between March and September 2018. Examination of 200 individuals from five species revealed the shark's predilection for targeting adult fish, ensuring efficient removal of energy‐rich tissue layers. However, a notable exception is Thunnus albacares, preyed on predominantly during its juvenile stage, possibly due to vertical spatial segregation. Recent bites were pervasive across species, with wahoo displaying a distinctive pattern. Cookiecutter shark bites predominantly targeted the lateral body portion (>55%) except for yellowfin tuna, which exhibited a preference for the ventral region (95%). The estimated length distribution suggests the SPSPA as a potential nursery area for cookiecutter sharks. Bite mark positions and frequencies may be linked to fish behavior, swimming velocity, and fishing gear strategy, highlighting the complex interplay in pelagic ecosystems.
Prospective comparative clinical study: Efficacy evaluation of collagen combined with hyaluronic acid injections for tear trough deformity
Authors: Liu Qing , Guo Lei , Zhu Yuhan , Song Binyu , Zeng Xianhui , Liang Zhen , Liu Jiaxi , Song Baoqiang 
Published: February 2024

AbstractBackgroundTear trough filling is a popular facial rejuvenation procedure, and hyaluronic acid is typically used as the filler of choice. However, Tyndall's phenomenon, a common complication following hyaluronic acid injection, can occur, leading to skin discoloration of the lower eyelid.AimsThis single‐center, prospective, comparative clinical study aimed to evaluate the efficacy of collagen and hyaluronic acid injections in treating tear trough deformity.MethodsSixty patients were enrolled between June 2022 and January 2023. Patients were randomly allocated into three groups: Group A received hyaluronic acid, Group B received hyaluronic acid combined with collagen, and Group C received collagen alone. Baseline characteristics, including age, sex, and tear trough deformity grade were considered before therapy. Changes in tear trough deformity scores, Global Aesthetic Improvement Scores, and the presence of the Tyndall effect were analyzed at 1 and 3 months postinjection to determine differences among the three groups.ResultsBaseline profiles of the three groups were similar. In the first month postinjection, there was no difference in the Global Aesthetic Improvement Scores and tear trough deformity between the three groups. However, in the third‐month postinjection, there was a significant difference in scores between patients in Group C and those in Groups A or B. The Tyndall effect manifested in three patients in Group A, which was significantly different from that in Groups B and C.ConclusionThe combined use of hyaluronic acid with collagen in injectable fillers corrected tear trough deformities and reduced the occurrence of the Tyndall phenomenon, which can be problematic with hyaluronic acid alone. Additionally, this combination may help overcome the disadvantage of a shorter retention period when using collagen alone.
Molecular characterization of mungbean yellow mosaic India virus infecting Vigna radiata in Oman
Authors: Shahid Muhammad Shafiq , Al‐Sadi Abdullah Mohammed 
Published: February 2024

AbstractThe full‐genome sequences of a bipartite begomovirus were identified in a mungbean (Vigna radiata) crop displaying symptoms such as yellow mosaics and stunting in the Al‐Batinah North region (23.6867° N 57.9058° E), Oman. Initial detection and confirmation of the virus genome were carried out through polymerase chain reaction, followed by obtaining complete genomes using rolling circle amplification. Bioinformatics analysis on both genomic components, DNA‐A and DNA‐B, revealed over 99% nucleotide sequence identity to the mungbean yellow mosaic India virus (MYMIV), previously known to infect tomato plants. Pairwise sequence analysis using the STD tool and subsequent phylogenetic analysis unveiled that the DNA‐A of the MYMIV isolate formed a cluster with closely related DNA‐A sequences of MYMIV from GenBank, while the DNA‐B clustered with the corresponding DNA‐B of the MYMIV isolate. Additionally, no evidence of recombination events was observed in the recombination analysis. Similarly, the nucleotide substitution rates between the DNA‐A and DNA‐B segments of MYMIV did not show significant differences. This finding represents the first documented instance of bipartite MYMIV infecting V. radiata in Oman.
Whole genome sequencing reveals stepping‐stone dispersal buffered against founder effects in a range expanding seabird
Authors: Herman Rachael W. , Clucas Gemma , Younger Jane , Bates John , Robinson Bryce , Reddy Sushma , Stepanuk Julia , O'Brien Katie , Veeramah Krishna , Lynch Heather J. 
Published: February 2024

AbstractMany species are shifting their ranges in response to climate‐driven environmental changes, particularly in high‐latitude regions. However, the patterns of dispersal and colonization during range shifting events are not always clear. Understanding how populations are connected through space and time can reveal how species navigate a changing environment. Here, we present a fine‐scale population genomics study of gentoo penguins (Pygoscelis papua), a presumed site‐faithful colonial nesting species that has increased in population size and expanded its range south along the Western Antarctic Peninsula. Using whole genome sequencing, we analysed 129 gentoo penguin individuals across 12 colonies located at or near the southern range edge. Through a detailed examination of fine‐scale population structure, admixture, and population divergence, we inferred that gentoo penguins historically dispersed rapidly in a stepping‐stone pattern from the South Shetland Islands leading to the colonization of Anvers Island, and then the adjacent mainland Western Antarctica Peninsula. Recent southward expansion along the Western Antarctic Peninsula also followed a stepping‐stone dispersal pattern coupled with limited post‐divergence gene flow from colonies on Anvers Island. Genetic diversity appeared to be maintained across colonies during the historical dispersal process, and range‐edge populations are still growing. This suggests large numbers of migrants may provide a buffer against founder effects at the beginning of colonization events to maintain genetic diversity similar to that of the source populations before migration ceases post‐divergence. These results coupled with a continued increase in effective population size since approximately 500–800 years ago distinguish gentoo penguins as a robust species that is highly adaptable and resilient to changing climate.
SNAC1‐OsERF103‐OsSDG705 module mediates drought response in rice
Authors: Yang Lijia , Xu Liang , Guo Jiazhuo , Li Aipeng , Qi Haoyue , Wang Jiaxuan , Song Shiyong 
Published: February 2024

Summary

Drought stress profoundly hampers both plant growth and crop yield. To combat this, plants have evolved intricate transcriptional regulation mechanisms as a pivotal strategy.

Through a genetic screening with rice genome‐scale mutagenesis pool under drought stress, we identified an APETALA2/Ethylene Responsive Factor, namely OsERF103, positively responds to drought tolerance in rice. Combining chromatin immunoprecipitation sequencing and RNA sequencing analyses, we pinpointed c. 1000 genes directly influenced by OsERF103.

Further results revealed that OsERF103 interacts with Stress‐responsive NAC1 (SNAC1), a positive regulator of drought tolerance in rice, to synergistically regulate the expression of key drought‐related genes, such as OsbZIP23. Moreover, we found that OsERF103 recruits a Su(var)3‐9,enhancer of zeste and trithorax‐domain group protein 705, which encodes a histone 3 lysine 4 (H3K4)‐specific methyltransferase to specifically affect the deposition of H3K4me3 at loci like OsbZIP23 and other genes linked to dehydration responses. Additionally, the natural alleles of OsERF103 are selected during the domestication of both indica and japonica rice varieties and exhibit significant geographic distribution.

Collectively, our findings have unfurled a comprehensive mechanistic framework underlying the OsERF103‐mediated cascade regulation of drought response. This discovery not only enhances our understanding of drought signaling but also presents a promising avenue for the genetic improvement of drought‐tolerant rice cultivars.
Detection of intact polyene pigments in Miocene gastropod shells
Authors: Wolkenstein Klaus , Schmidt Burkhard C. , Harzhauser Mathias 
Published: February 2024

AbstractPolyene pigments represent a major class of pigments in present‐day organisms. Their occurrence in fossils has been frequently discussed, but to date no spectroscopic evidence has been found. Here, we use in situ Raman spectroscopy to examine the chemistry of exceptionally well‐preserved gastropod shells with colour preservation from the Middle Miocene of the Vienna Basin (Austria, Hungary). Raman signals indicative of the presence of intact (i.e. non‐hydrogenated) polyene pigments were obtained from fossil shells with reddish colour patterns, thus revealing the first record of intact polyenes in fossils. The observed Raman values are in good agreement with those of unmethylated (non‐carotenoid) polyenes. Fossil polyene pigments were detected in representatives of the superfamily Cerithioidea, but not in representatives of other gastropod families with colour preservation found at the same localities, demonstrating that the occurrence of polyene pigments is taxon‐specific. Our results show that Raman spectroscopy represents a valuable tool for the non‐destructive screening of rare fossils with colour preservation for the occurrence of polyene pigments.
Infantile anogenital digitate keratoses
Authors: Savard Sophie‐Anne , Powell Julie , Marcoux Danielle , Coulombe Jérôme 
Published: February 2024

AbstractInfantile anogenital digitate keratoses (IADK) represent a distinct and under‐recognized pediatric condition of the perianal area of infants, significantly more frequent in males than females. The average age of onset is 3.2 months, and it is self‐remitting by 2 years of age. Perianal spiny keratoses resistant to usual topical therapies are the hallmark of IADK. We present a series of three cases of IADK seen at the dermatology clinic of the CHU Sainte‐Justine to raise awareness on this pediatric condition, and to prevent invasive workup.
Mapping the intersection of social determinants of health, postpartum visit attendance, and pregnancy‐related deaths: A scoping review
Authors: Ware Katilya S. , Thompson Claire , Renfroe Karol , Grabowsky Adelia , Onuorah Peace O. , Williams Courtney H. 
Published: February 2024

AbstractBackgroundMaternal health outcomes in the United States raises concern due to elevated rates of pregnancy‐related deaths compared to other developed and underdeveloped countries. This scoping review explores relationships between social determinants of health (SDOH), postpartum visit attendance, and pregnancy‐related deaths.MethodsUtilizing the Arksey and O'Malley framework and PRISMA‐Scr guidelines, a systematic review was conducted to identify pertinent literature.ResultsEight studies were analyzed, providing insights into SDOH, postpartum visits, and pregnancy‐related deaths. The findings highlight healthcare access/quality, economic stability, education, and social/community context as influential in postpartum care utilization. Health insurance emerges a key factor for postpartum attendance. In addition, disparities in geographic access to maternity care services were linked to pregnancy‐related deaths. Social contextual factors, such as marital status and social support, exhibited varying associations with postpartum visit attendance.ConclusionWhile the analyzed studies provided valuable insight, there remains a gap in the literature examining all three key elements: SDOH, postpartum visit attendance, and pregnancy‐related deaths. In conclusion, this scoping review highlights the vital role of addressing social determinants in improving maternal health outcomes. Further research is necessary to better inform interventions to reduce pregnancy‐related deaths.