bluuebunny/crossref_metadata_2025_split huggingface dataset:
Young evolutionary origins of dioecy in the genus Asparagus
Authors: Bentz Philip C. , Liu Zhengjie , Yang Jun‐Bo , Zhang Le , Burrows Sandra , Burrows John , Kanno Akira , Mao Zichao , Leebens‐Mack Jim 
Published: February 2024

AbstractPremiseDioecy (separate sexes) has independently evolved numerous times across the angiosperm phylogeny and is recently derived in many lineages. However, our understanding is limited regarding the evolutionary mechanisms that drive the origins of dioecy in plants. The recent and repeated evolution of dioecy across angiosperms offers an opportunity to make strong inferences about the ecological, developmental, and molecular factors influencing the evolution of dioecy, and thus sex chromosomes. The genus Asparagus (Asparagaceae) is an emerging model taxon for studying dioecy and sex chromosome evolution, yet estimates for the age and origin of dioecy in the genus are lacking.MethodsWe use plastome sequences and fossil time calibrations in phylogenetic analyses to investigate the age and origin of dioecy in the genus Asparagus. We also review the diversity of sexual systems present across the genus to address contradicting reports in the literature.ResultsWe estimate that dioecy evolved once or twice approximately 2.78−3.78 million years ago in Asparagus, of which roughly 27% of the species are dioecious and the remaining are hermaphroditic with monoclinous flowers.ConclusionsOur findings support previous work implicating a young age and the possibility of two origins of dioecy in Asparagus, which appear to be associated with rapid radiations and range expansion out of Africa. Lastly, we speculate that paleoclimatic oscillations throughout northern Africa may have helped set the stage for the origin(s) of dioecy in Asparagus approximately 2.78−3.78 million years ago.
Co(II), Mn(II), and Fe(III) complexes of water‐soluble hydrazone bearing 2‐nicotinoylhydrazineylidene moiety: Preparation, characterization, cyclic voltammetry, computational and biological studies
Authors: Mohammed Mahdi A. , Fetoh Ahmed , Ali Tamer Awad , Youssef Magdy M. , El‐Reash Y. G. Abou , Abu El‐Reash Gaber M. 
Published: February 2024

A water‐soluble hydrazone ligand bearing 2‐nicotinoylhydrazineylidene moiety, sodium 4‐hydroxy‐3‐([2‐nicotinoylhydrazineylidene]methyl) benzenesulfonate (NaH2NH), and its complexes with Co(II), Fe(III), and Mn(II) have been synthesized and characterized. The structure of the ligand and its complexes were analyzed using various spectroscopic techniques such as FT‐IR, 1H‐ and 13C‐NMR, EI‐mass, powder X‐ray diffraction, UV–visible spectra, and magnetic measurements. The infrared spectra indicated that the ligand behaves as a negatively charged bidentate ligand (ON) through the deprotonation of the enolic (OH) group and the azomethine (C=N) group in the [Co (NaHNH)2(H2O)4Cl2].3H2O complex. In the [Fe (NaNH)2(H2O)Cl].2H2O complex, the ligand behaves as bi‐negative tetradentate (O2N2) through the protonation of the enolic oxygen and the nitrogen atom of the azomethine group in two nicotinic hydrazone molecules. Another coordination type was observed for [Mn (NaNH)(H2O)3] complex in which NaH2NH acts as bi‐negative tridentate ONO through the nitrogen atom of the azomethine group, the protonated of enolic and phenolic groups. The fluorescence spectrum of the NaH2NH was found to be quenched upon addition of these Co(II) and Mn(II) ions. The antimicrobial results indicated that the Mn(II) complex exhibited the highest antibacterial potency against all targeted organisms. The results of antioxidants demonstrated that the complexes exhibited higher activity compared to the free ligand, indicating an enhancement of antioxidant activity through complexation. The tested substances established strong nuclease‐like activity at a high concentration of 7.5 mM, leading to the complete degradation of DNA as observed in agarose gel electrophoresis. This suggests that these compounds have the potential to serve as antitumor agents in vivo by inhibiting DNA replication in cancer cells and preventing tumor growth. The interaction of the isolated compounds with 1c14 and 6vj3 targets was discussed using molecular docking.
Wall mosaics of Thessaloniki: A comparative study of the brown tesserae
Authors: Kyranoudi Maria , Malletzidou Lamprini , Zorba Triantafillia , Vourlias George , Melfos Vasilios , Pavlidou Eleni , Chrissafis Konstantinos 
Published: February 2024

AbstractThe present study focuses on the archaeometric investigation of 10 brown tesserae belonging to Early Christian/Byzantine wall mosaics of three monuments of Thessaloniki, inscribed on the World Heritage List of UNESCO: Rotunda, St. Sophia, and St. Demetrios. The tesserae were analyzed via optical microscopy (OM), scanning electron microscopy‐energy dispersive spectroscopy (SEM‐EDS), X‐ray diffraction (XRD), and UV‐Vis reflectance spectroscopy to define their composition and technological characteristics. Nine of the tesserae are made of silica glass while one tessera is made of a siliceous rock. The majority of the glass tesserae, despite the chronological distance of the monuments they were collected from, present similar technological features, base glass composition, colorants, and opacifiers. Metallic copper is the main element responsible for the brown color in relation to iron which serves as a reducing agent. Opacification is attributed to tin compounds.
Biochar‐based catalysts derived from biomass waste: production, characterization, and application for liquid biofuel synthesis
Authors: Nguyen Van Nhanh , Sharma Prabhakar , Rowinski Lech , Le Huu Cuong , Le Duc Trong Nguyen , Osman Sameh M. , Le Huu Son , Truong Thanh Hai , Nguyen Phuoc Quy Phong , Cao Dao Nam 
Published: February 2024

AbstractAmong the feasible options for valorizing lignocellulosic biomass into value‐added products, biochar is considered to be extremely appealing and it could be applied easily in several established thermochemical processes. Biochar possesses a large surface area due to its porous nature, which permits easy use in various applications, including catalytic biofuel production. This work summarizes research on biochar generation processes, its critical physicochemical properties, and factors that influence them. Important studies adopting biochar catalysts for liquid biofuel production are critically reviewed, and the reaction mechanisms and biofuel yield are analyzed. Finally, challenges in the use of biochar‐based catalysts for biofuel production are presented, together with possible solutions. In general, this current work aims to provide the critical characteristics of biochar as a potential catalyst to biofuel synthesis toward sustainable bioenergy production.
Estimation of spectral similarities utilizing segmented regions' probability distribution in the block‐optimized pan‐sharpened image for material classification
Authors: S Jayashree , V. Karki Maya , K Indira , P A Dinesh 
Published: February 2024

AbstractPan‐sharpening is an image fusion approach that combines the spectral information in multispectral (MS) images with the spatial properties of PAN (Panchromatic) images. This vital technique is used in categorization, detection, and other remote sensing applications. In the first step, the article focuses on increasing the finer spatial details in the MS image with PAN images using two levels of fusion without causing spectral deterioration. The suggested fusion method efficiently utilizes image transformation techniques and spatial domain image fusion methods. The luminance component of MS images typically contains spatial features that are not as detailed as the PAN images. A multiscale transform is applied to the intensity/luminance component and PAN image to introduce features into the intensity component. In the first level of processing, coefficients obtained from the non‐subsampled contourlet transform are subjected to particle swarm optimization weighted block‐based fusion. The second level of fusion is carried out using the concept of spatial frequency to reduce spectral distortion. Numerous reference and non‐reference parameters are used to evaluate the sharpened image's quality. In the next step, the article focuses on designing an evaluation metric for analysing spectral distortion based on the Bhattacharyya coefficient and distance. The Bhattacharyya coefficient and distance are calculated for each segmented region to assess the sharpened images' quality. Spectral degradation analysis using proposed techniques can also be useful for analysing materials in the segmented regions. The research findings demonstrate that the spatial features of fused images obtained from the proposed technique increased with the least spectral degradation.
Navigating a net‐zero economy future: Antecedents and consequences of net‐zero economy‐based green innovation
Authors: Mehmood Khalid , Kautish Pradeep , Mangla Sachin Kumar , Ali Ahsan , Kazancoglu Yigit 
Published: February 2024

AbstractThe pursuit of net‐zero economy goals and government emphasis on sustainable performance has compelled numerous firms to focus on sustainable production through the adoption of net‐zero economy‐based green innovation. The digital transformation of manufacturing systems and supply chains, supported by the utilization of big data and the adoption of net‐zero economy‐oriented lean practices in the presence of net‐zero economy‐based green practices, can converge to enhance net‐zero economy‐based green innovation in manufacturing firms. This convergence leads to an improvement in green competitive advantage and net zero‐based green performance. To examine the aforementioned linkages using a framework based on the dynamic capabilities view paradigm, a time‐lagged design was employed to collect data from 594 manufacturing firms. The empirical findings indicate that big data analytics capabilities and net‐zero economy‐oriented lean practices of firms significantly influence net‐zero economy‐based green innovation. Green organizational identity strengthens the effect of net zero‐based green innovation on green competitive advantage and net zero‐based green performance.
Real‐world analysis of adverse event rates after initiation of ibrutinib among Medicare beneficiaries with chronic lymphocytic leukemia
Authors: Huntington Scott F. , de Nigris Enrico , Puckett Justin T. , Kamal‐Bahl Sachin , Farooqui Mohammed , Ryland Katherine , Sarpong Eric M. , Leng Siyang , Yang Xiaoqin , Doshi Jalpa A. 
Published: February 2024

AbstractBackgroundThe first‐generation BTK inhibitor ibrutinib is a standard‐of‐care therapy in the treatment of chronic lymphocytic leukemia (CLL) despite potential side effects that often lead to discontinuation.MethodsThis study used 2013–2019 claims data to describe the incidence rate of adverse events (AEs) among elderly Medicare beneficiaries newly initiating ibrutinib for CLL.ResultsThe final sample contained 11,870 Medicare beneficiaries with CLL (mean age 77.2) newly initiating ibrutinib, of whom 65.2% discontinued over mean follow‐up of 2.3 years. The overall incidence rate of AEs was 62.5 per 1000 patient‐months for all discontinuers and 32.9 per 1000 patient‐months for non‐discontinuers. Discontinuers had a higher incidence rate of AEs per 1000 patient‐months compared with non‐discontinuers for all AEs examined, including infection (22.8 vs. 14.5), atrial fibrillation (15.1 vs. 7.0), anemia (21.9 vs. 14.5), and arthralgia/myalgia (19.5 vs. 13.6).ConclusionIn this first real‐world study of a national sample of elderly US patients treated with ibrutinib, we found a clear unmet need for improved management of ibrutinib‐related AEs and/or new treatments to improve real‐world outcomes in patients with CLL.
Antimicrobial peptide mimetic minimalistic approach leads to very short peptide amphiphiles‐gold nanostructures for potent antibacterial activity
Authors: Swain Narayan , Sharma Shruti , Maitra Rahul , Saxena Deepanshi , Kautu Aanand , Singh Ramesh , Kesharwani Khushboo , Chopra Sidharth , Joshi Khashti Ballabh 
Published: February 2024

AbstractStrategically controlling concentrations of lipid‐conjugated L‐tryptophan (vsPA) guides the self‐assembly of nanostructures, transitioning from nanorods to fibres and culminating in spherical shapes. The resulting Peptide‐Au hybrids, exhibiting size‐controlled 1D, 2D, and 3D nanostructures, show potential in antibacterial applications. Their high biocompatibility, favourable surface area‐to‐volume ratio, and plasmonic properties contribute to their effectiveness against clinically relevant bacteria. This controlled approach not only yields diverse nanostructures but also holds promise for applications in antibacterial therapeutics.
H2O2 Self‐Supplying CaO2/CuO2/Fe3O4 Nanoplatform for Enhanced Chemodynamic Therapy of Cancer Cells
Authors: Liu Bojian , Wang Xiaohui , Yang Wei , Peng Hongshang , Zhang Hongxin 
Published: February 2024

AbstractDue to the properties of hypoxia, lower pH, and higher hydrogen peroxide (H2O2) in the tumor microenvironment (TME), a wide variety of metal peroxide nanomaterials have got great attention for efficient TME‐responsive and ‐regulated tumor therapy. However, a single species of metal peroxide is inadequate to realize high effective anticancer therapy. Herein, we have synthesized a hyaluronic acid (HA) modified CaO2/CuO2/Fe3O4 nanocomposite by a simple and flexible strategy. CaO2 can generate H2O2 by reacting with water in slightly acidic TME, and the self‐supplying H2O2 can be catalyzed to generate ⋅OH by both Cu2+ and Fe2+ via Fenton‐type reaction. Strongly oxidizing ⋅OH can induce tumor cells death for enhanced chemodynamic therapy (CDT). The H2O2 self‐supplying and ⋅OH self‐catalyzed nanocomposite exhibited favorable pH‐controlled ⋅OH generation and excellent cancer cells growth inhibition ability, providing a potential nanotheranostics platform with active targeting and favorable therapeutic efficacy in tumor therapy.
AE‐Integrated: Real‐time network intrusion detection with Apache Kafka and autoencoder
Authors: Roshan Khushnaseeb , Zafar Aasim 
Published: February 2024

SummaryUnknown cyber‐attack detection in network traffic streams is challenging but crucial to ensure network security. It is observed that new security threats occur on a daily basis and make cyberspace vulnerable. In the literature, machine learning and deep learning‐based network intrusion detection systems have gained a lot of success but still face many challenges in detecting new security threats and unknown cyber‐attacks in real‐time. Additionally, high false alarm rates and real‐time detection in constantly evolving high‐dimensional network data streams are open issues for the research community. To address this issue, a DL‐based solution is developed to detect real‐time network anomalies in streaming data with high detection accuracy, precision, recall and low false negative and positive scenarios. The proposed novel algorithm, AE‐Integrated, is developed and evaluated on the latest CICIDS‐2017 dataset. The AE‐Integrated is updated with the newest network traffic data stream by the human administrator after a certain period to maintain its prediction accuracy for future inference. The simulation study is conducted with the Apache Kafka and Slack API to get real‐time anomaly alerts. Finally, we compared the result with recent state‐of‐the‐art research to evaluate the significance of the proposed algorithm. It is concluded that combining multiple lightweight autoencoders into a single large architecture provides optimal results. The accuracy, recall, and AUC of AE‐Integrated obtained are 99.54%, 99.53%, and 0.998, respectively.
Green, Low‐carbon Silk‐based Materials in Water Treatment: Current State and Future Trends
Authors: Sun Yuxu , Ma Lantian , Wei Tiancheng , Zheng Meidan , Mao Chuanbin , Yang Mingying , Shuai Yajun 
Published: February 2024

AbstractThe improper and inadequate treatment of industrial, agricultural, and household wastewater exerts substantial pressure on the existing ecosystem and poses a serious threat to the health of both humans and animals. To address these issues, different types of materials have been employed to eradicate detrimental pollutants from wastewater and facilitate the reuse of water resources. Nevertheless, owing to the challenges associated with the degradation of these traditional materials post‐use and their incompatibility with the environment, natural biopolymers have garnered considerable interest. Silk protein, as a biomacromolecule, exhibits advantageous characteristics including environmental friendliness, low carbon emissions, biodegradability, sustainability, and biocompatibility. Considering recent research findings, this comprehensive review outlines the structure and properties of silk proteins and offers a detailed overview of the manufacturing techniques employed in the production of silk‐based materials (SBMs) spanning different forms. Furthermore, it conducts an in‐depth analysis of the state‐of‐the‐art SBMs for water treatment purposes, encompassing adsorption, catalysis, water disinfection, desalination, and biosensing. The review highlights the potential of SBMs in addressing the challenges of wastewater treatment and provides valuable insights into prospective avenues for further research.
Synthesizing Hypercrosslinked Polymers with Deep Eutectic Solvents to Enhance CO2/N2 Selectivity
Authors: Ding Liang , Chanchaona Nadhita , Konstas Kristina , Hill Matthew R. , Fan Xianfeng , Wood Colin D. , Lau Cher Hon 
Published: February 2024

AbstractHypercrosslinked polymers (HCPs) are widely used in ion exchange, water purification, and gas separation. However, HCP synthesis typically requires hazardous halogenated solvents e. g., dichloroethane, dichloromethane and chloroform which are toxic to human health and environment. Herein we hypothesize that the use of halogenated solvents in HCP synthesis can be overcome with deep eutectic solvents (DES) comprising metal halides–FeCl3, ZnCl2 that can act as both the solvent hydrogen bond donor and catalyst for polymer crosslinking via Friedel Crafts alkylation. We validated our hypothesis by synthesizing HCPs in DESs via internal and external crosslinking strategies. [ChCl][ZnCl2]2 and [ChCl][FeCl3]2 was more suitable for internal and external hypercrosslinking, respectively. The specific surface areas of HCPs synthesized in DES were 20–60 % lower than those from halogenated solvents, but their CO2/N2 selectivities were up to 453 % higher (CO2/N2 selectivity of poly‐α,α’‐dichloro‐p‐xylene synthesized in [ChCl][ZnCl2]2 via internal crosslinking reached a value of 105). This was attributed to the narrower pore size distributions of HCPs synthesized in DESs.
IBRtools: An R package for calculating integrated biomarker indexes
Authors: Resende Anna Carolina , Pereira Diego Mauro Carneiro 
Published: February 2024

AbstractMultibiomarker studies are useful to evaluate the early warning signs of environmental degradation, and their unified responses are often assessed through two common indexes, Integrated Biomarker Response (IBR) and Integrated Biological Responses version 2 (IBRv2). The R package IBRtools allows users to calculate both IBR and IBRv2 while simultaneously incorporating all the biomarkers under evaluation. The package includes functions for calculating the indexes IBR and IBRv2 and obtaining their standardized values, as well a function for radar chart creation and three example datasets. Here we describe the main algorithms involved in IBR and IBRv2 calculations, a description of the novel package and illustrate a workflow using data examples available on the package to guide the user on how to accurately acquire the values for either the IBR index or the IBRv2 index. The IBRtools package provides a user‐friendly platform for R users to obtain IBR index and IBRv2 values, making it straightforward even for large datasets.
Accelerating the open research agenda to solve global challenges
Authors: Zagrodzka Zuzanna B. , Johnson Thomas F. , Beckerman Andrew P. 
Published: February 2024

AbstractHarnessing science‐based policy is key to addressing global challenges like the biodiversity and climate crises. Open research principles underpin effective science‐based policy, but the uptake of these principles is likely constrained by the politicisation, commoditisation and conflicting motives of stakeholders in the research landscape. Here, using the mission and vision statements from 129 stakeholders from across the research landscape, we explore alignment in open research principles between stakeholders. We find poor alignment between stakeholders, largely focussed around journals, societies and funders, all of which have low open research language‐use. We argue that this poor alignment stifles knowledge flow within the research landscape, ultimately limiting the mobilisation of impactful science‐based policy. We offer recommendations on how the research landscape could embrace open research principles to accelerate societies' ability to solve global challenges.
New species and new record of Statherotmantis Diakonoff, 1973 from China (Lepidoptera: Tortricidae: Olethreutinae)
Authors: Jing Wenqing , Niu Zehua , Ma Shuang , Yu Haili 
Published: February 2024

AbstractIn China, six species of Statherotmantis Diakonoff, 1973 were previously recorded. In the present study, four other species were recognized using morphology and DNA barcording analysis. Among these, three of which, S. miniscula sp. n., S. calva sp. n., and S. longiuscula sp. n., are described as new. In addition, one species, S. laetana Kuznetzov, 1988, is a new record for China. Adults and genitalia are illustrated, and keys to identify the Chinese species of Statherotmantis are provided.
Application of intense pulsed light in the development of poly(vinyl butyral)‐based all‐solid‐state Ag/AgCl reference electrodes
Authors: Krivačić Sara , Zubak Marko , Vrsaljko Domagoj , Kassal Petar 
Published: February 2024

AbstractIntense pulsed light was investigated for partial photoreduction of AgCl in a poly(vinyl butyral) matrix to obtain a Ag/AgCl reference membrane. The membrane was deposited on both glassy carbon and inkjet‐printed silver electrodes giving all‐solid‐state reference electrodes. Regardless of the electrode material, a sufficient potential stability was obtained in a broad concentration range of various salt solutions. Long‐term potential stability was significantly improved with inkjet‐printed silver electrical contacts. The electroanalytical performance of inkjet‐printed electrodes was successfully demonstrated in potentiometric and amperometric systems.