bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intrinsic brain functional connectivity predicts treatment-related motor complications in early Parkinson’s disease patients
Authors: De Micco Rosa , Di Nardo Federica , Siciliano Mattia , Silvestro Marcello , Russo Antonio , Cirillo Mario , Tedeschi Gioacchino , Esposito Fabrizio , Tessitore Alessandro 
Published: October 2023

Abstract
Background
Treatment-related motor complications may develop progressively over the course of Parkinson’s disease (PD).

Objective
We investigated intrinsic brain networks functional connectivity (FC) at baseline in a cohort of early PD patients which successively developed treatment-related motor complications over 4 years.

Methods
Baseline MRI images of 88 drug-naïve PD patients and 20 healthy controls were analyzed. After the baseline assessments, all PD patients were prescribed with dopaminergic treatment and yearly clinically re-assessed. At the 4-year follow-up, 36 patients have developed treatment-related motor complications (PD-Compl) whereas 52 had not (PD-no-Compl). Single-subject and group-level independent component analyses were used to investigate FC changes within the major large-scale resting-state networks at baseline. A multivariate Cox regression model was used to explore baseline predictors of treatment-related motor complications at 4-year follow-up.

Results
At baseline, an increased FC in the right middle frontal gyrus within the frontoparietal network as well as a decreased connectivity in the left cuneus within the default-mode network were detected in PD-Compl compared with PD-no-Compl. PD-Compl patients showed a preserved sensorimotor FC compared to controls. FC differences were found to be independent predictors of treatment-related motor complications over time.

Conclusion
Our findings demonstrated that specific FC differences may characterize drug-naïve PD patients more prone to develop treatment-related complications. These findings may reflect the presence of an intrinsic vulnerability across frontal and prefrontal circuits, which may be potentially targeted as a future biomarker in clinical trials.
No evidence that coring affects tree growth or mortality in three common European temperate forest tree species
Authors: Portier Jeanne , Shackleton Ross T. , Klesse Stefan , Ferretti Marco , Flury Roman , Hobi Martina L. , Stillhard Jonas , von Arx Georg , Rohner Brigitte , Thürig Esther 
Published: October 2023

AbstractTree cores are a highly valuable scientific resource. Annual growth ring data can, for example, improve our understanding of climate change impacts and effects of environmental pollution, allow for better annual estimations of tree growth patterns and carbon storage, and help quantify dynamics and changes in forest ecosystems. The value of coring trees for research has been weighted against concerns around the potential harm coring might cause to trees. To date, there is indeed limited research accurately quantifying the potential effects of coring on tree growth and only a handful of studies assessing its influence on mortality. Consequently, many European long-term forest inventorying and monitoring programs are concerned that tree coring might bias the repeated tree measurements in permanent plots, which they rely on for assessments of states and changes of forests. In this study, we assessed the effects of tree coring on the growth and mortality of three widespread European tree species approximately 10 years after they were cored. We used repeated tree measurements from permanent research sites in Switzerland and Ukraine. In Switzerland, we assessed 35 cored and 159 uncored Norway spruce (Picea abies) trees as well as 147 cored and 332 uncored silver fir (Abies alba) trees. In Ukraine, we assessed 348 cored and 6′611 uncored European beech (Fagus sylvatica) trees. We found no statistical evidence that coring negatively affected the growth or mortality of the three tree species assessed. Although we cannot rule out subtle effects on tree health and wood quality, our findings do not provide any evidence that coring affects or biases repeated measurements (such as DBH measures and recording of mortality) performed on the investigated tree species. Tree coring could therefore be considered more often for routine incorporation, particularly in long-term forest inventorying and monitoring programs and initiatives.
Nitrogen fixation associated with epiphytes on the seagrass Zostera marina in a temperate lagoon with moderate to high nitrogen loads
Authors: Marino Roxanne , Hayn Melanie , Howarth Robert W. , Giblin Anne E. , McGlathery Karen J. , Berg Peter 
Published: October 2023

AbstractAs part of a long-term study on the effects of nitrogen (N) loading in a shallow temperate lagoon, we measured rates of N2 fixation associated with seagrass (Zostera marina) epiphytes during the summer from 2005 to 2019, at two sites along a gradient from where high N groundwater enters the system (denoted SH) to a more well-flushed outer harbor (OH). The data presented here are the first such long-term N2 fixation estimates for any seagrass system and one of the very few reported for the phyllosphere in a temperate system. Mean daily N2 fixation was estimated from light and dark measurements using the acetylene reduction assay intercalibrated using both incorporation of 15N2 into biomass and a novel application of the N2:Ar method. Surprisingly, despite a large inorganic N input from a N-contaminated groundwater plume, epiphytic N2 fixation rates were moderately to very high for a seagrass system (OH site 14-year mean of 0.94 mmol N m−2 d−1), with the highest rates (2.6 mmol N m−2 d−1) measured at the more N-loaded eutrophic site (SH) where dissolved inorganic N was higher and soluble reactive phosphorus was lower than in the better-flushed OH. Over 95% of the total N2 fixation measured was in the light, suggesting the importance of cyanobacteria in the epiphyte assemblages. We observed large inter-annual variation both within and across the two study sites (range from 0.1 to 2.6 mmol N fixed m−2 d−1), which we suggest is in part related to climatic variation. We estimate that input from phyllosphere N2 fixation over the study period contributes on average an additional 20% to the total daily N load per area within the seagrass meadow.
Adapting E-cigarette prevention programming to reach the latinx community
Authors: Herrmann Alison K. , Ferullo Sylvia Lopez , Hernandez Miriam , Barriga Verónica Arciga , Leggis Bernadett , Ruiz Julissa , Glenn Beth A. , Bastani Roshan 
Published: October 2023

Abstract
Purpose
E-cigarettes are the most commonly used tobacco product among youth in the United States. Yet evidence-based prevention programming is limited due to the rapid onset of this threat. Community-based efforts to address vaping largely target youth in school settings. Although parents can play an important role in youth tobacco control efforts, messages about the dangers of vaping, use among adolescents, and strategies for intervening have not reached many Spanish-speaking parents in low-income Latinx communities. Our community-academic team developed e-cigarette prevention programming for use by promotor/as de salud to address this unmet need.

Methods
During the 1-year project, the team worked closely with a Project Advisory Committee to: review existing evidence-informed materials; conduct focus groups with parents, youth and promotor/as to guide program development; develop a curriculum to prepare promotor/as to educate low-literacy, Spanish-speaking parents about vaping; craft Spanish language resources for promotor/as to use in community education sessions; train 61 promotor/as to deliver the program; and support program delivery to 657 community members.

Results
Focus groups with promotor/as and community members, key-informant interviews, and brief surveys informed program development and assessment. Community member feedback was essential to development of appropriate materials. Promotor/as demonstrated significant pre- to post- training increases in e-cigarette knowledge and confidence in delivering vaping prevention education. Community members demonstrated a mastery of basic e-cigarette concepts and expressed intention to discuss vaping with their children.

Conclusions
Promotor/a-led programming for parents represents a promising approach to vaping prevention and control in the Latinx community.
The irrigated wheat initiative of Ethiopia: a new paradigm emulating Asia’s green revolution in Africa
Authors: Effa Kefena , Fana Daniel Muleta , Nigussie Mandefro , Geleti Diriba , Abebe Nigusie , Dechassa Nigussie , Anchala Chimdo , Gemechu Getu , Bogale Teshome , Girma Dejene , Berisso Feto Esimo 
Published: October 2023

Abstract
The aim of this paper is to assess and document the experience of the successful irrigated wheat initiative in Ethiopia, identify potential limitations, and suggest alternative options that contribute towards the sustainability of the program. In the past decades, Ethiopia has initiated several projects to ensure food and wheat security but did not achieve the anticipated impact as planned. In 2019, however, the current government of Ethiopia put in place structural, economic, and sectorial reforms, with wheat chosen as a strategic commodity for food security, raw material for the agroindustry, import substitution that transits to export, and job creation along the value chain. With a total of 2.6 million ha of land cultivated under both rain-fed and irrigated systems, followed by a record amount of wheat harvest (8.2 million tons) in 2022, Ethiopia achieved a wheat self-sufficiency ratio of 100% and more than 1 million tons of surplus for export, indicating that the new irrigated wheat initiative of Ethiopia has been found transformational and is becoming a game changer. Moreover, modest case scenario projections revealed that Ethiopia will become a net exporter of wheat by 2023, indicating that the country is achieving not only wheat security but also championing the possibility of replicating Asia’s Green Revolution in Africa. Yet, the sustainability of the current initiative relies on an efficient water management system, private sector engagement, sustainable input supply, well-established input and output marketing systems, and leadership commitment at all levels.
Contextualizing and hybridizing academic identity formation: an analysis of international returnees and locally trained scholars in China
Authors: Dai Kun , Hardy Ian 
Published: October 2023

AbstractAcademic identity formation is strongly influenced by higher education contexts. In the past decades, the Chinese higher education sector has attempted to integrate academic internationalization at the local level. In this context, international returnees and locally trained scholars may encounter different issues in the process of constructing academic identities at various stages of their careers. However, relatively few studies have critically analyzed how international returnees and locally trained scholars understand their academic identity formation during their student years, as they transition to becoming academics, and as they begin to become more established in academic roles under increasingly complex global-national-local conditions. Drawing upon the concept of social hybridization and the notion of global-national-local imbrications, this narrative study investigates six scholars’ trajectories of academic identity formation across different stages of the early phase of their careers, including during their doctoral studies and their initial period as early career academics. The findings show that academics’ identity development entails a process of struggle and confusion during earlier stages through to the construction of a more hybrid academic identity. By exploring the challenges and issues experienced by different cohorts of academics, scholars may better understand the internationalization of Chinese higher education and interweaving relationships with the global context.
Fundamental Equation of State for Fluid Tetrahydrofuran
Authors: Fiedler Felix , Karog Joel , Lemmon Eric W. , Thol Monika 
Published: October 2023

AbstractAn empirical fundamental equation of state in terms of the Helmholtz energy for tetrahydrofuran is presented. In the validity range from the triple-point temperature up to 550 K and pressures up to 600 MPa, the equation of state enables the calculation of all thermodynamic properties in the liquid, vapor, and super-critical regions including saturation states. Based on an extensive literature review, experimental data are represented within their experimental uncertainty. In the homogeneous liquid phase at atmospheric pressure, the uncertainty in density is 0.015 %, speed of sound is represented with an uncertainty of 0.03 %, and isobaric heat capacity has an uncertainty of 0.4 %. Isobaric heat capacities in the homogeneous vapor phase are described with an uncertainty of 0.2 %. Higher uncertainties occur above atmospheric pressure for all homogeneous properties. Depending on the temperature range, vapor pressure can be calculated with an uncertainty from 0.02 % to 3 %. The extrapolation behavior is evaluated, showing reasonable extrapolation behavior towards extreme conditions.
Response inhibition training as an intervention to modify liking and wanting for foods based on energy density: a proof of concept study
Authors: Moore Halim , White Melanie J. , Finlayson Graham , King Neil 
Published: October 2023

AbstractThe ubiquity of energy-dense, processed foods has been implicated as a salient feature of the modern ‘obesogenic’ environment. Cognitive strategies, such as response inhibition training, have been demonstrated to reduce the hedonic value of such foods in previous studies. However, this effect has generally been inconsistent or heterogenous, depending on the outcome measure, characteristics of the sample, and the specificity of food stimuli. Characterising the extent of generalised effects may help define the application of this type of intervention in natural settings. A repeated-measures, proof-of-concept study, using mobile app-based response inhibition training (RIT) versus a control app-based activity (N = 25), was undertaken to establish the valid application of a food reward measure to assess intervention efficacy. Liking (i.e., affect) and wanting (i.e., motivation) for food stimuli categorised by energy density were taken concurrently pre- and post-training. A statistically significant reduction in explicit liking, but not implicit wanting, for foods irrespective of their energy density was observed during the RIT app-based training session relative to the control (p = .041, ηp2 = .16). However, effect sizes associated with devaluation of energy-dense relative to low calorie food stimuli, although non-significant, were higher when measured as implicitly wanting (p = .098, ηp2 = .11) than explicit liking (p = .756, ηp2 = .00). Trends in explicit stimulus evaluations were empirically discordant from implicit evaluations for low calorie foods in particular. Additional research is needed to investigate whether these trends are reproducible with larger samples, trained and novel food stimuli in outcome measures, and more comprehensive training protocols.
Truth Meets Vagueness. Unifying the Semantic and the Soritical Paradoxes
Authors: Bruni Riccardo , Rossi Lorenzo 
Published: October 2023

AbstractSemantic and soritical paradoxes display remarkable family resemblances. For one thing, several non-classical logics have been independently applied to both kinds of paradoxes. For another, revenge paradoxes and higher-order vagueness—among the most serious problems targeting solutions to semantic and soritical paradoxes—exhibit a rather similar dynamics. Some authors have taken these facts to suggest that truth and vagueness require a unified logical framework, or perhaps that the truth predicate is itself vague. However, a common core of semantic and soritical paradoxes has not been identified yet, and no explanation of their relationships has been provided. Here we aim at filling this lacuna, in the framework of many-valued logics. We provide a unified diagnosis of semantic and soritical paradoxes, identifying their source in a general form of indiscernibility. We then develop our diagnosis into a theory of paradoxicality, which formalizes both semantic and soritical paradoxes as arguments involving specific instances of our generalized indiscernibility principle, and correctly predicts which logics can non-trivially solve them.
Maternal Dietary Patterns and Risk of Postpartum Depression: A Systematic Review
Authors: Sun Yuyue , Ferguson Megan , Reeves Marina M. , Kelly Jaimon T. 
Published: October 2023

Abstract
Objective
Postpartum depression (PPD) has deleterious effects on both maternal and child outcomes. Poor maternal nutrition during pregnancy has been implicated in the development of PPD. This review aimed to explore the association between the overall dietary intake patterns during pregnancy and the development of PPD.

Methods
A literature search was performed in PubMed, Embase, Scopus, CINAHL, and PsycINFO databases for relevant randomized controlled trials, cohort and cross-sectional studies published up to 17th September 2020. Included studies assessed at least one dietary pattern during pregnancy and reported on PPD. The Newcastle Ottawa Scale and the Joanna Briggs Institute critical appraisal tools were used to assess the quality of methodology. A narrative analysis was conducted.

Results
Ten studies (eight cohort and two cross-sectional) were included with substantial heterogeneity in measurements of dietary intake exposures and PPD. The studies identified several types of healthy dietary patterns, including a ‘healthy’, ‘health conscious’, ‘Japanese’, ‘high-glycemic index/glycemic load’, ‘Vegetable’, ‘Nut-Fruit’, ‘Seafood’, and ‘compliance with the Australian Dietary Guidelines’. The ‘Western’, ‘unhealthy’, ‘Beverage’, ‘Cereal-Meat’, and ‘Egg’ were labelled as unhealthy dietary patterns. Four of the eight studies showed an inverse association between adherence to healthy diets and risk of PPD, whereas only one of the seven studies showed that adherence to unhealthy diets was associated with increased risk of PPD. Methodological quality of the studies varied across the sample.

Conclusions
Our findings indicate that adherence to a healthy diet may be beneficial for PPD. However, the relationship between unhealthy diets and PPD needs to be corroborated by more high-quality studies.
Exudyn – a C++-based Python package for flexible multibody systems
Authors: Gerstmayr Johannes 
Published: October 2023

AbstractThe present contribution introduces the design, methods, functionalities, and capabilities of the open-source multibody dynamics code Exudyn, which has been developed since 2019. The code has been designed for rigid and flexible multibody systems, with a focus on performance for multicore desktop processors. It includes script-language-based modeling and it is intended to be used in science and education, but also in industry. The open-source code is available on GitHub and consists of a main C++ core, a rich Python interface including pre- and postprocessing modules in Python, and a collection of rigid and flexible bodies with appropriate joint, load, and sensor functionality. Integrated solvers allow explicit and implicit time integration, static solution, eigenvalue analysis, and optimization. In the paper, the code design, structure, computational core, computational objects, and multibody formulations are addressed. In addition, the computational performance is evaluated with examples of rigid and flexible multibody systems. The results show the significant impact of multithreading especially for small systems, but also for larger models.
Investigation of the driving characteristics of electric bicycles by means of multibody simulation
Authors: Bolk Johannes , Corves Burkhard 
Published: October 2023

AbstractElectrically assisted bicycles lead to a change in the driving characteristics compared to conventional bicycles because of the additionally attached masses of motor and battery. In order to describe the resulting interaction of the electric drive components on the driving characteristics, this paper examines simulations of the driving behavior of bicycles with different positions of battery and motor in open- and closed-loop tests. The integration of human driving behavior by control loops allows the evaluation of driving characteristic under more realistic driving conditions compared to the existing studies of the eigenbehavior. The results are analyzed using characteristic values that describe the system behavior in a suitable way. Furthermore, a design of experiments is performed to classify the influence of the presented research results in relation to other system parameters, such as different types of bicycles and different rider postures.
Are models our tools not our masters?
Authors: Jacobs Caspar 
Published: October 2023

AbstractIt is often claimed that one can avoid the kind of underdetermination that is a typical consequence of symmetries in physics by stipulating that symmetry-related models represent the same state of affairs (Leibniz Equivalence). But recent commentators (Dasgupta in Philos Perspect 25:115–160, 2011; Pooley in: Knox and Wilson (eds) The Routledge companion to the philosophy of physics, Routledge, Milton Park, 2021; Pooley and Read in Br J Philos Sci, 2021, https://doi.org/10.1086/718274; Teitel in J Philos 119:233–278, 2021) have responded that claims about the representational capacities of models are irrelevant to the issue of underdetermination, which concerns possible worlds themselves. In this paper I distinguish two versions of this objection: (1) that a theory’s formalism does not (fully) determine the space of physical possibilities, and (2) that the relevant notion of possibility is not physical possibility. I offer a refutation of each.
Intricate relationship between obstructive sleep apnea and dementia in older adults
Authors: Ercolano Erica , Bencivenga Leonardo , Palaia Maria Emiliana , Carbone Giovanni , Scognamiglio Francesco , Rengo Giuseppe , Femminella Grazia Daniela 
Published: October 2023

AbstractNumerous evidence reports direct correlation between cognitive impairment, Alzheimer’s disease and sleep disorders, in particular obstructive sleep apnea. Both obstructive sleep apnea and Alzheimer’s disease are highly prevalent conditions whose incidence increases with age. Several studies demonstrate how sleep-disordered breathing may lead to poor cognition, even though the underlying mechanisms of this association remain partially unclear. According to the most recent studies, obstructive sleep apnea may be considered a modifiable risk factor for cognitive dysfunction. In the present review, the authors aim to integrate recent research examining obstructive sleep apnea and Alzheimer’s disease biomarkers, also focusing on the mechanisms that support this correlation, including but not limited to the role of hypoxia and cardiovascular risk. Moreover, the potential favourable effect of obstructive sleep apnea therapy on cognitive function is discussed, to evaluate the benefits deriving from appropriate treatment of sleep-disordered breathing on cognition.