bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brainstem tumors in children: a monocentric series in the light of genetic and bio-molecular progress in pediatric neuro-oncology
Authors: Boukaka Rel Gerald , Beuriat Pierre-Aurélien , Di Rocco Federico , Vasiljevic Alexandre , Szathmari Alexandru , Mottolese Carmine 
Published: October 2023

IntroductionBrainstem tumors represent a challenge. Their management and prognosis vary according to anatomopathological findings and genetic and bio-molecular fingerprints. We present our experience with pediatric brainstem tumors.Material and methodsAll patients admitted for a brainstem tumor at the Pediatric Neurosurgical Unit at Hôpital Femme Mère Enfant hospital between January 1997 and December 2019 were considered. Patients data were obtained through a retrospective review of the medical records; follow-up was from the last outpatient consultation.ResultsOne hundred and twelve patients were included. Eighty-five patients (75.9%) had open surgery or stereotactic biopsy. Thirty-five patients were treated for hydrocephalus. Sixty-six received an adjuvant treatment. Several protocols were adopted according to the SFOP and SIOP during this time period. The overall survival rate was 45% with a median follow-up of five years (range 1–18 year). However, the survival rate was very different between the diffuse intrinsic pontine gliomas (DIPG) and the others tumor types. If we exclude the DIPG (59 patients), of which only 1 was alive at 3 years, the survival rate was 90.6% (only 5 deaths over 53 patients) with a median follow up of 5 years.ConclusionsOur series confirms that benign tumors of the brainstem have a good survival when treated with surgical removal ± adjuvant therapy. Diffuse pontine gliomas continue to have a dismal prognosis. Individualized treatment based on molecular fingerprints may help to select the best adjuvant therapy and hence potentially improve survival.
Green synthesis of silver nanoparticles from plant Fagonia cretica and evaluating its anti-diabetic activity through indepth in-vitro and in-vivo analysis
Authors: Khan Haider Ali , Ghufran Mehreen , Shams Sulaiman , Jamal Alam , Khan Abbas , Abdullah  , Awan Zuhier A. , Khan Mohammad Imran 
Published: October 2023

One of the most widespread metabolic diseases, Type-2 Diabetes Mellitus (T2DM) is defined by high blood sugar levels brought on by decreased insulin secretion, reduced insulin action, or both. Due to its cost-effectiveness and eco-friendliness, plant-mediated green synthesis of nanomaterials has become more and more popular. The aim of the study is to synthesize AgNPs, their characterizations and furtherin-vitroandin-vivostudies. Several methods were used to morphologically characterise the AgNPs. The AgNPs were crystalline, spherical, and clustered, with sizes ranging from 20 to 50 nm. AgNPs were found to contain various functional groups using Fourier transform infrared spectroscopy. This study focuses on the green-synthesis of AgNPs fromFagonia cretica(F. cretica) leaves extract to evaluate their synthesized AgNPs forin-vitroandin-vivoanti-diabetic function. For thein-vivotests, 20 male Balb/C albino-mice were split up into four different groups. Anti-diabeticin-vivostudies showed significant weight gain and a decrease in all biochemical markers (pancreas panel, liver function panel, renal function panel, and lipid profile) in Streptozotocin (STZ)-induced diabetic mice.In vitroanti-diabetic investigations were also conducted on AgNPs, comprising α-amylase, α-glucosidase inhibitions, and antioxidant assays. AgNPs showed antioxidant activity in both the DPPH and ABTS assays. The research showed that the isolated nanoparticles have powerful antioxidant and enzyme inhibitory properties, especially against the main enzymes involved in T2DM.
Law matters – assessment of country-level code implementation and sales of breastmilk substitutes in South Asia
Authors: Ching Constance , Sethi Vani , Nguyen Tuan Thanh , Murira Zivai , Shats Katherine , Rowel Dhammica , Ahmed Khadheeja , Dorji Kinley , Chakma Indrani , Haag Karan Courtney , Singh Phulgendra Prasad , Khatoon Salma , Bukhari Uzma Khurram , Aminee Ahmadwali , Ghosh Sebanti , Forissier Thomas , Kappos Kristen , Zambrano Paul , Khan Golam Mohiuddin 
Published: October 2023

ObjectivesThis study examines the status of implementation of the International Code of Marketing of Breast-milk Substitutes of eight countries in the South Asia region (Afghanistan, Bangladesh, Bhutan, India, Maldives, Nepal, Pakistan, and Sri Lanka), and describes the sales value and volume of commercial milk formula (CMF) marketed as breastmilk substitutes (BMS) and baby food in four countries (Bangladesh, India, Pakistan, and Sri Lanka).DesignA mix of descriptive methods is used to assess national status of Code implementation, including a desk review of the 2022 WHO/UNICEF/IBFAN Code Status Report, systematic content analysis of national Code measures, and insights generated from the participation of key government and UNICEF/WHO actors in a regional workshop that aimed to identify each country’s barriers, gaps, and the status of Code implementation. Data on the sales value and volume of CMF and baby food between 2007 to 2021 and with the prediction to 2026 in Bangladesh, India, Pakistan, and Sri Lanka were obtained from Global Data.FindingsThere are major gaps in Code implementation in countries even with legal measures considered substantially aligned with the Code, such as the inadequate age range of CMF covered in the scope, insufficient safeguards against conflicts of interest in the health system, lack of warning of risks of intrinsic contamination of powdered milk formula, and an absence of effective monitoring and enforcement mechanisms. Data on CMF sales shows health facilities and pharmacies sustain the highest sales. Lower sales volume of infant formula (including special formula), compared to other CMF such as follow-up formula and growing-up milk, has been observed in three of the four countries (Bangladesh, India, and Sri Lanka). Overall, GUM, followed by baby cereals, accounted for a large portion of CMF and baby foods sales in the same three countries.Recommended actions include(1) Closing the gaps between national measures and the Code, (2) Ensuring effective monitoring and enforcement mechanisms, (3) Strengthening conflicts of interest safeguards in the health system, (4) Tackling digital marketing, and (5) Galvanizing political support and support from in-country public health and women’s rights jurist networks.
HUBUNGAN BEBAN KERJA FISIK DAN STRES KERJA DENGAN KELELAHAN KERJA PADA PEKERJA KONVEKSI NAZKIA DI DESA SUKAMUKTI KECAMATAN CIKIJING KABUPATEN MAJALENGKA TAHUN 2023
Authors: Lutfiah Evie , Heriana Cecep , Saprudin Ade 
Published: October 2023

Menurut International Labour Organization (ILO) menyatakan bahwa hampir setiap tahun sebanyak dua juta pekerja meninggal dunia karena kecelakaan kerja yang disebabkan oleh faktor kelelahan. Dalam penelitian tersebut menjelaskan dari 58.115 sampel, 32,8% diantaranya mengalami kelelahan. Penelitian ini bertujuan untuk mengetahui hubungan antara beban kerja fisik dan stress kerja dengan kelelahan kerjapada pekerja konveksi Nazkia di Desa Sukamukti Kecamatan Cikijing Kabupaten Majalengka Tahun 2023. Metode :Jenis penelitian ini adalah survei analitik dengan rancangan penelitian cross sectional. Subjek penelitian ini adalah seluruh penjahit di konveksi gamis, sampel yang digunakan sebanyak 37 responden. Teknik pengambilan sampel menggunakan teknik total sampling. Instrumen yang digunakan yaitu alat ukur pulse oximeter, wawancara dan kuesioner. Analisis bivariat yaitu uji korelasi rank spearman. Hasil : Analisis univariat diperoleh variabel beban kerja fisik sebagian besar mengatakan beban kerja berat (40,5%), pada variabel stress kerja sebagian besar mengatakan stress kerja tinggi (56,8%). Hasil uji statistik beban kerja fisik diperoleh p-value = 0,000 dan R = 0,860 dan stress kerja diperoleh p-value = 0,000 dan nilai R = 0,902. Simpulan : Ada hubungan antara beban kerja fisik dan stress kerja dengan kelelahan kerjapada pada pekerja konveksi Nazkia di Desa Sukamukti Kecamatan Cikijing Kabupaten Majalengka Tahun 2023. Saran : Pekerja perlu menerapkan pola hidup sehat, melakukan peregangan otot, mengelola stress dan menerapkan peraturan shift kerja.
ANALISIS PENYEBAB DEMAM BERDARAH DENGUE (DBD) DI KELURAHAN TELADAN KECAMATAN TOBOALI KABUPATEN BANGKA SELATAN
Authors: Hasna'Rizqia Achmada  , Andini  , Siti Hafifah  , Oki Saputra  , Miranda  , Salabyla RiqqohZakiyah  , Dliya Putri  , Umar Rizki Fitroni Merciandy  , Diana Indin Pramasuri  , Bunga Regina Putri  , Asyraf Suryadin  
Published: October 2023

Penyakit Demam Berdarah Dengue atau DBD merupakan penyakit menular yang dapat menyebabkan kematian sehingga masyarakat perlu mengetahui berbagai macam penyebab wabah penyakit ini terjadi dan untuk mencegah penularannya. Oleh karena itu , didalam artikel ini penulis akan menganalisis berbagai macam penyebab terjadinya demam berdarah Dengue khususnya di kelurahan Teladan kecamatan Toboali kabupaten Bangka Selatan pada tahun 2023 karena kasus demam berdarah Dengue atau DBD dikelurahan teladan meningkat di dua tahun terakhir . Penulis menggunakan Metode kualitatif deskriptif dalam penelitian ini. Adapun hasil penelitian yang didapat dari wawancara Masyarakat dan observasi lingkungan yang didapatkan adalah bahwa penyebab terjadinya penyakit Demam Berdarah Dengue atau DBD di kelurahan teladan adalah Banyaknya tumpukan sampah disekitar rumah ,kurangnya kebersihan dikamar tidur, menggantung baju atau pakaian ditempat yang lembab, banyaknya genangan air seperti dibelakang kulkas dan didalam botol sampah dan juga kepadatan penduduk . Lalu, untuk pencegahan dan penanggulanngan yang dapat dilakukan adalah dengan mebiasakan hidup bersih dan sehat.
PELATIHAN MANAJEMEN USAHA MELALUI MEDIA SOSIAL BAGI PELAKU USAHA DESA SERDANG BANGKA SELATAN
Authors: Wawan Maman Chahyono , Ariyanto  , Fatimah Nurul Janah  , Fatimah Nurul Janah  
Published: October 2023

Keberadaan Usaha Mikro Kecil dan Menengah (UMKM) di Desa Serdang mempunyai potensi dan peran yang besar dalam membangun perekonomian. Namun jenis UMKM masih kurang dikenal oleh masyarakat luas. Banyak masalah yang harus dihadapi oleh pelaku UMKM dari aspek pemasaran, produksi dan sumber daya manusia. Di Desa Serdang terdapat beberapa UMKM antara lain roti papan, trasi limus, jahe merah, dan krupuk kemplang. Promosi yang diterapakan sekedar dari mulut ke mulut, pengemasan produk yang tidak menarik dan tidak memiliki media sosial sama sekali. Keterbatasan tersebut merupakan permasalahan yang harus diatasi oleh pelaku UMKM. Artikel ini difokuskan pada dampak pelatihan UMKM serta perubahan apa yang didapat baik itu dari aspek penjualan, packaging, dan pendapatan. Tujuan dari pelatihan ini yaitu masyarakat dapat mengetahui cara promosi, packaging, dan foto produk secara mandiri. Pelatihan dan penyuluhan ini memberikan manfaat bagi masyarakat khususnya para pemilik usaha di Desa Serdang. Metode yang digunakan pada penelitian ini adalah sosialisasi dan pelatihan secara langsung terkait pemasaran, packaging, dan foto produk. Sekaligus mengajak pelaku usaha untuk konsisten dalam menjalankan usaha. Dari hasil penelitian ini menunjukan peningkatkan diberbagai aspek manajemen dari cara memasarkan produk hingga packaging yang menarik. Tak hanya itu pelaku usaha sudah melakukan foto produk secara mandiri hingga meningkatkannya pendapatan.
REVITALISASI EKONOMI MASYARAKAT MELALUI PEMANFAATAN POHON RUMBIA (Metroxylon sagu) SEBAGAI BAHAN BAKU PEMBUATAN KUE SAGU MELALUI PEMANFAATAN MARKETPLACE
Authors: Titi Nurhasanah  , Laila sely mahfiroh  , Rizqi Aminulloh  , Rajab Vebrian  
Published: October 2023

Revitalisasi ekonomi adalah kegiatan yang dilakukan untuk menggiatakan ekonomi yang dapat meningkatkan produktivitas dan nilai tambah. Pohon rumbia merupakan sumber daya alam yang sangat berpengaruh bagi kehidupan manusia,diantaranya manfaatnya yaitu diolah menjadi sagu. Pohon rumbia juga dapat menghasilkan pendapatan bagi masyarakat khususnya di Desa Air Menduyung melalui pemanfaatan produk kue sagu. Dalam upaya meningkatkan kemampuan dan potensi yang dimiliki masyarakat sehingga masyarakat dapat mewujudkan diri dalam mengembangkan di bidang ekonomi dan sosial budaya . Penelitian ini bertujuan untuk melihat peningkatan ekonomi penjualan kue sagu melalui media online (marketplace) produk kue sagu yang dihasilkan dapat dijual lebih luas dan mencapai konsumen di berbagai daerah. Penelitian ini mengunakan metode penelitian dengan teknik analisis deskriptif. Teknik pengumpulan data yang digunakan yaitu observasi dan wawancara. Melakukan riset awal untuk memahami bagaimana pohon rumbia dapat diolah menjadi bahan baku kue sagu yang berkualitas, dengan strategi yang tepat dan komitmen yang kuat, Produk ini memiliki potensi untuk menghasilkan dampak positif pada ekonomi masyarakat lokal, menjaga lingkungan, dan mempromosikan produk khas daerah melalui marketplace secara berkelanjutan.
PENYULUHAN DAMPAK PERNIKAHAN DINI TERHADAP PSIKOLOGI ANAK PADA MASYARAKAT DESA AIR PUTIH
Authors: Ridho al akbar  , Siti Zainab  , Izzatun Nisa  , Tasya Setiawan  , Melvin Arfian Dita  , Maulana Oscard Nasution  , Ainun Makrun  , Yuli Setyaningsih  , Melan  , Akbar Maria Ulfa Zhinensis  , M. Iqbal Arrosyad  
Published: October 2023

Fenomena pernikahan dini di Desa Air Putih menjadi sorotan karena jumlahnya yang semakin meningkat. Interaksi guru dengan murid yang cukup intens, dapat menjadi peluang bagi guru untuk memberikan pemahaman bagi siswa serta orang tua siswa mengenai kerugian atau dampak negatif dari pernikahan dini. Tujuan pengabdian kepada masyarakat ini adalah untuk memberikan pemahaman akan bahaya pelaksanaan pernikahan dini dan diharapkan bahwa dengan program penyuluhan ini dapat meningkatkan kesadaran hukum pernikahan dini kepada masyarakat Desa Air Putih. Metode yang digunakan berupa penyuluhan dan sosialisasi dengan target sasaran anak SMP. Yang dimana penyuluhan ini membahas tentang apa itu pernikahan dini, dampak negatif dan faktor yang mempengaruhi pernikahan dini. Hasil penelitian ini dapat disimpulkan bahwa pemerintah harus menerapkan kebijakan sertifikat layak nikah karena angka penceraian yang semakin meningkat, kesehatan reproduksi wanita yang bermasalah, banyaknya anak yang stunting karena disebabkan oleh ibu yang menikah di bawah batas usia, dan meningkatnya KDRT. Penyebabnya juga faktor budaya lokal yang di pengaruhi oleh sistem sosial dan tradisi nikah muda yang diwariskan oleh keluarga. Sedangkan dampaknya menjadikan anak untuk putus sekolah, hilangnya hak reproduksi anak yang disebabkan hamil duluan,sehingga membuat seorang anak harus melahirkan diusia muda.
Kata kunci: penyuluhan, pernikahan dini, spikologi anak.
UPAYA MENGEMBANGKAN WISATA EDUKASI DI BUKIT BATU INDAH DESA PANGEK
Authors: Rizko Ramadhan  , Aizah Cahyaningrum  , Hermalia Putri  , Fandi Nugroho  
Published: October 2023

Abstrak: Pengabdian ini dilakukan di Desa Pangek, Simpang Tritip, Bangka Barat. Desa Pangek memiliki potensi wisata berbasis komoditas yaitu bukit batu indah yang ditanami dengan banyaknya pohon durian. Bukit ini sudah lama tidak aktif atau kurang dirawat oleh masyarakat selama empat tahun terakhir. Dengan pengangkatan wisata edukasi dibukit batu menjadi nilai tambah untuk Desa Pangek sehingga akan berdampak positif bagi perekonomian masyarakat setempat. Tujuan dari pengabdian ini meliputi (1) Mengaktifkan kembali potensi durian yang ada di Desa Pangek, (2) Pelatihan kesadaran masyarakat dalam pengembangan daya tarik wisata edukasi, (3) Memberikan rekomendasi pengelolaan wisata edukasi dan pariwisata berkelanjutan kepada pengelola destinasi wisata Desa Pangek. Metode pengabdian masyarakat yang diterapkan meliputi observasi, pelatihan, dan pendampingan. Partisipasi masyarakat dinilai belum maksimal dalam pengembangan wisata. Hasil pelatihan dengan 30 responden 70% masyarakat menyadari akan pentingnya pengolahan wisata edukasi durian dengan memberikan pelatihan dan pendampingan sesuai kebutuhan masyarakat dalam mengelola dan pengembangan wisata, kemudian melakukan promosi untuk meningkatkan minat dari wisata durian.
Kata Kunci: durian; wisata edukasi; potensi
Mechanical properties and cohesive energies of BiSeTe and BiSbTe
Authors: Yamaguchi Shigeo 
Published: October 2023

Abstract
The author studied the thermal and mechanical properties of bulk Bi2Se0.19Te2.94 and Bi0.35Sb1.50Te3, focusing on the estimation of cohesive energy using the potential energies of these materials based on their thermal and mechanical characteristics. By implementing the potential energy of a pair of atoms in the materials developed in two types of expression, the author found that the cohesive energies of Bi2Se0.19Te2.94 and Bi0.35Sb1.50Te3 are 2100 and 4200 kJ mol−1, respectively. By comparing the properties of NaCl and SiC, the author demonstrated that Bi2Se0.19Te2.94 is covalent and slightly ionic, whereas Bi0.35Sb1.50Te3 is strongly covalent.
3D structure of threading screw dislocation at a deep location in 4H-SiC using 3D micro-X-ray topography
Authors: Ishiji Kotaro , Yoneyama Akio , Inaba Masayuki , Fukuda Kazunori , Sakaki Atsushi , Ohmagari Shinya , Sugie Ryuichi 
Published: October 2023

Abstract
We used 3D micro-X-ray topography (3D μ-XRT) to construct a 3D structure of the threading screw dislocations (TSDs) in 4H-SiC. The 00012 diffraction condition, which can observe the strain field at a deep location in the sample, was employed in the 3D μ-XRT geometry. The dislocation core-lines of TSDs propagating from the surface to the interior of the sample were successfully captured spatially, and TSDs parallel to and inclined from the 〈0001〉 axis were both confirmed. Either the component 〈

1

¯

1

¯

20

〉 or 〈

1

¯

100

〉 of the Burgers vector is considered to be mixed in the inclined TSD. To verify this suggestion, scanning electron microscopy (SEM) and cathodoluminescence (CL) spectroscopy were performed on the molten-alkali-etched TSDs. Both the SEM shapes and CL intensities of the TSD etch pits with inclination showed the features of the mixed component, supporting the correlation between the inclination and mixed component in TSD.
Elastography and Steatometry of the Liver from the Position of World Experts 2018–2022
Authors: Borsukov A. V. , Venidiktova D. Yu. , Skutar A. I. , Ahmedova A. R. 
Published: October 2023

Purpose: To evaluate the dynamics of the opinions of world experts on the materials of world recommendations on ultrasound elastography and liver steatometry from the standpoint of the domestic level of development of ultrasound diagnostics and on the basis of our own data.Material and methods: 16 main provisions of the World Guidelines for Liver Elastography in 2018 were reviewed and comments were made, differences from the European Guidelines of 2017 and the first World Guidelines of 2015 were noted. We reviewed and commented on the 2020 SRU comments. The final scientific publication of a large group of world experts in 2022 is analyzed in detail, where for the first time the norms and threshold values between benign and malignant neoplasms of a large number of human organs and tissues are given.Results: From 2006 to the present, more than 45,000 ultrasound studies have been carried out on our own material (n=15627), some differences in approaches to liver elastometry are given, and approaches to the use of ultrasound steatometry are considered.Conclusion: Threshold development vectors are shown, techniques to avoid artifacts and reduce the risk of obtaining false negative and false positive elastometry results are proposed. There is caution of the expert community in the review of the method of quantitative steatometry based on the measurement of the attenuation coefficient of the ultrasound wave.
Hello from the other side: Robust contralateral interference in tactile detection
Authors: Kusnir Flor , Pesin Slav , Landau Ayelet N. 
Published: October 2023

AbstractTouch is unique among the sensory modalities in that our tactile receptors are spread across the body surface and continuously receive different inputs at the same time. These inputs vary in type, properties, relevance according to current goals, and, of course, location on the body. Sometimes, they must be integrated, and other times set apart and distinguished. Here, we investigate how simultaneous stimulation to different body sites affects tactile cognition. Specifically, we characterized the impact of irrelevant tactile sensations on tactile change detection. To this end, we embedded detection targets amidst ongoing performance, akin to the conditions encountered in everyday life, where we are constantly confronted with new events within ongoing stimuli. In the set of experiments presented here, participants detected a brief intensity change (.04 s) within an ongoing vibrotactile stimulus (1.6 s) that was always presented in a constantly attended location. The intensity change (i.e., the detection target) varied parametrically, from hardly detectable to easily detectable. In half of the trials, irrelevant ongoing stimulation was simultaneously presented to a site across the body midline, but participants were instructed to ignore it. In line with previous bimanual studies employing brief onset targets, we document robust interference on performance due to the irrelevant stimulation at each of the measured body sites (homologous and nonhomologous fingers, and the contralateral ankle). After describing this basic phenomenon, we further examine the conditions under which such interference occurs in three additional tasks. In each task, we honed in on a different aspect of the stimulation protocol (e.g., hand distance, the strength of the irrelevant stimulation, the detection target itself) in order to better understand the principles governing the observed interference effects. Our findings suggest a minimal role for exogenous attentional capture in producing the observed interference effects (Exp. 2), and a principled distribution of attentional resources or sensory integration between body sides (Exps. 3, 4). In our last study (Exp. 4), we presented bilateral tactile targets of varying intensities to both the relevant and irrelevant stimulation sites. We then characterized the degree to which the irrelevant stimulation is also processed. Our results—that participants’ perception of target intensity is always proportional to the combined bilateral signal—suggest that both body sites are equally weighed and processed despite clear instructions to attend only the target site. In light of this observation and participants’ inability to use selection processes to guide their perception, we propose that bilateral tactile inputs are automatically combined, quite possibly early in the hierarchy of somatosensory processing.