bluuebunny/crossref_metadata_2025_split huggingface dataset:
Führungskompetenzen im Zeitalter der Künstlichen Intelligenz
Authors: Bock Tobias , von der Oelsnitz Dietrich 
Published: October 2023

Abstract
Künstliche Intelligenz (KI) wird durch die automatisierte Verarbeitung von großen Mengen an Daten und Informationen, Entscheidungen in Unternehmen umfangreich verändern. Diese Transformation bringt neue Chancen für Unternehmen mit sich wie beispielsweise bessere und schneller Entscheidungen und Herausforderungen wie beispielsweise die Akzeptanz und Umsetzung der KI ermittelten Entscheidungen. Um diese Transformation nachhaltig zu bewältigen und mögliche negativen Auswirkungen zu minimieren ist der effektive Umgang der Führung in der Einführung und Nutzung der Technologie unerlässlich. Basierend auf einer strukturierten Literaturrecherche und Interviews mit KI- und HR-Experten in der deutschen Automobilindustrie wurden Führungskompetenzen identifiziert, die im Zeitalter der KI relevant sein werden. Dieser kurze Studienbericht trägt zur Erweiterung des Wissens über Führungstheorien bei und bietet eine Grundlage für zukünftige Führungskräften-Entwicklungsprogrammen.
Dichtheitstests an Batteriezellen im Takt der Serienproduktion
Authors: Seitz Sandra 
Published: October 2023

Abstract
In der Elektromobilität kommt der Traktionsbatterie eine Schlüsselrolle zu. Keine andere Komponente im Elektrofahrzeug ist so bedeutsam und wertvoll wie seine Batterie. Ein Großteil der Wertschöpfung beginnt mit der einzelnen Lithium-Ionen-Zelle, dem kleinsten und wichtigsten Bestandteil der Antriebsbatterie. Für die Qualität und Sicherheit von Lithium-Ionen-Zellen ist ihre dauerhafte Dichtheit ein entscheidendes Kriterium. So ist unbedingt zu vermeiden, dass in eine Zelle im Laufe ihres Lebenszyklus Wasserdampf eintritt, denn das Wasser würde mit dem Elektrolyten der Zelle zu giftiger Flusssäure reagieren. Umgekehrt darf aber auch kein Elektrolyt austreten, denn dies würde die Kapazität und die Lebensdauer der Batteriezelle stark beeinträchtigen. Aussagefähige Dichtheitsprüfungen sind darum, auch in der Zellen-Massenfertigung unabdingbar. Die Aufgabe besteht darin, in der Serienfertigung jede einzelne Lithium-Ionen-Zelle sorgfältig auf ihre Dichtheit zu prüfen.
APP substrate ectodomain defines amyloid‐β peptide length by restraining γ‐secretase processivity and facilitating product release
Authors: Koch Matthias , Enzlein Thomas , Chen Shu‐Yu , Petit Dieter , Lismont Sam , Zacharias Martin , Hopf Carsten , Chávez‐Gutiérrez Lucía 
Published: October 2023

AbstractSequential proteolysis of the amyloid precursor protein (APP) by γ‐secretases generates amyloid‐β (Aβ) peptides and defines the proportion of short‐to‐long Aβ peptides, which is tightly connected to Alzheimer's disease (AD) pathogenesis. Here, we study the mechanism that controls substrate processing by γ‐secretases and Aβ peptide length. We found that polar interactions established by the APPC99 ectodomain (ECD), involving but not limited to its juxtamembrane region, restrain both the extent and degree of γ‐secretases processive cleavage by destabilizing enzyme–substrate interactions. We show that increasing hydrophobicity, via mutation or ligand binding, at APPC99‐ECD attenuates substrate‐driven product release and rescues the effects of Alzheimer's disease‐associated pathogenic γ‐secretase and APP variants on Aβ length. In addition, our study reveals that APPC99‐ECD facilitates the paradoxical production of longer Aβs caused by some γ‐secretase inhibitors, which act as high‐affinity competitors of the substrate. These findings assign a pivotal role to the substrate ECD in the sequential proteolysis by γ‐secretases and suggest it as a sweet spot for the potential design of APP‐targeting compounds selectively promoting its processing by these enzymes.
Addressing the Impact of Racism On the Mental Health of Youth: A Focus On Pediatric Health Professionals and Collaborators
Authors: Breland-Noble Alfiee M. , Weller Bridget E. , Patterson Akilah , Anderson Riana Elyse 
Published: October 2023

Racism in all forms, including racial discrimination, historical racism, structural oppression, and institutional discrimination, has well-documented adverse effects on the mental health of children and adolescents. It is associated with suicidal ideation, depression, anxiety, substance misuse, and behavioral issues. In this chapter, we detail the effects of racism on the mental health of youth of color from birth to 25 years of age and provide recommendations for pediatric health professionals and collaborators to mitigate the adverse influence of racism on youth mental health.
Keywords: racism, mental health, youth
Book Sharing and Children’s Literature As a Strategy for Facilitating Conversations On Race
Authors: Navsaria Dipesh 
Published: October 2023

Book sharing can play an essential role in anti-racism work with families. Fundamentally, reading books together serves several critical functions, not all of which are the exclusive domain of conversations around racism and discrimination. Sharing books offers a route for building vital elements of relational health. It is a foundation for family discussions where parents or caregivers can play that all-important, sense-making role for their children as they explore and wonder about the world around them. Book sharing can create a scaffold for conversations or ease the route into discussing topics, particularly if they are not necessarily easy to take on.
Keywords: book selection, reading aloud, children’s literature
The Role of Quality and Safety in Furthering Health Equity
Authors: Kim Julia M. , Jackson Meghan Drayton , Shah Rahul 
Published: October 2023

Equity is 1 of 6 goals for improvement in health care quality, in addition to safety, effectiveness, timeliness, patient centeredness, and efficiency, as outlined in 2001 by the Institute of Medicine, now known as the National Academy of Medicine. Quality and safety are crucial in dismantling racism and furthering health equity. In this chapter, we review the evidence and describe action steps that pediatric health professionals and teams can take to achieve health equity in the context of quality and safety.
Keywords: quality improvement, patient safety, equity
Toma de decisiones basadas en la evidencia: un enfoque de codiseño para la información sobre biodiversidad en los Andes tropicales
Authors: Valdez Jose W. , Pereira Henrique M. , Morejón Gustavo Francisco , Acosta‐Muñoz Cristina , Garcia Francisco Javier Bonet , Vergara Lucía Castro , Claros Xavier R. , Gill Michael J. , Josse Carmen , Lafuente‐Cartagena Indyra , Langstroth Robert , Sheppard Sidney Novoa , Orihuela Gabriela , Prieto‐Albuja Francisco J. , Quillahuaman Natividad , Terán Marcos F. , Zambrana‐Torrelio Carlos M. , Navarro Laetitia M. , Fernandez Miguel 
Published: October 2023

La conservación de la biodiversidad es un problema complejo y transdisciplinario que requiere el compromiso y la cooperación entre instituciones científicas, sociales, económicas y políticas. Sin embargo, los enfoques tradicionales/convencionales a menudo no logran reunir y abordar las necesidades de todos los actores relevantes en los procesos de toma de decisiones. Los Andes tropicales, un área clave de biodiversidad donde los esfuerzos de conservación a menudo entran en conflicto con cuestiones socioeconómicas y políticas que priorizan el desarrollo económico, proporcionan un modelo ideal para desarrollar e implementar enfoques más efectivos. En este estudio, presentamos un enfoque co-diseño que integra y mejora el flujo de información sobre biodiversidad en los Andes tropicales, creando resultados personalizados que satisfacen las necesidades, tanto económicas como sociales, de las partes interesadas. Empleamos un proceso de consulta que reunió a usuarios y productores de información sobre biodiversidad a nivel local, nacional y regional, a través de encuestas y talleres. Este enfoque ha permitido identificar necesidades prioritarias y limitaciones del flujo de información sobre biodiversidad en la región; lo cual llevó al codiseño de indicadores de biodiversidad relevantes para los usuarios. Aprovechando las capacidades existentes de los usuarios y productores de información sobre biodiversidad, pudimos co-diseñar múltiples indicadores de biodiversidad y priorizar dos de estos para su implementación completa, asegurando que los datos sean localizables, accesibles, interoperables y reutilizables, según los principios FAIR. Este enfoque ayudó a abordar las limitaciones que se identificaron en el proceso de participación de las partes interesadas; incluidas las brechas en la disponibilidad de datos y la necesidad de información sobre biodiversidad más accesible. Además, se incorporaron talleres de desarrollo de capacidades para todos los productores de información sobre biodiversidad involucrados, los cuales apuntaron no sólo a mejorar el flujo actual de información sobre biodiversidad en la región, sino también facilitar su sostenibilidad futura. Nuestro enfoque puede servir como un modelo valioso para incorporar la información sobre biodiversidad y hacerla más inclusiva en el futuro; especialmente si consideramos las diversas perspectivas globales, valores y sistemas de conocimiento implicados en las interacciones entre la ciencia, la política y su aplicación práctica.
The Pecos Array: A Temporary Nodal Seismic Experiment in the Pecos, Texas, Region of the Delaware Basin
Authors: Faith Jenna L. , Karplus Marianne S. , Veitch Stephen A. , Doser Diane I. , Savvaidis Alexandros 
Published: October 2023

Abstract
With increasing earthquakes in the Delaware basin since 2009, earthquake studies, including accurate hypocenters, are critically needed in the Delaware basin to identify the structures producing earthquakes, and to determine if they are related to unconventional petroleum development and production. In 2018, with funding from the Texas Seismological Network, we deployed and maintained a nodal network of 25 Magseis Fairfield Z-Land Generation 2 5-Hz seismic nodes in the Pecos, Texas, region of the Delaware basin, known as, The Pecos Array. The network was deployed from November 2018 to the beginning of January 2020, with an additional two months of data recorded in September and October 2020. The network collected continuous three-component data with a 1000-Hz sampling rate. The spacing of the nodes varied from ∼2 km in town to ∼10 km farther away from the city center. The primary goal of this network was to improve estimation of event hypocenters, which will help to determine why there has been an increase in earthquakes over the past several years. In this article, we summarize the scientific motivation, deployment details, and data quality of this network. Data quality statistics show that we successfully collected continuous data with signal-to-noise ratios that allow us to detect and locate events, hundreds of them being estimated at ML&lt;0.50. This unique dataset is contributing to new seismotectonic studies in the Delaware basin.
Liver parenchyma dissection in Totally robotic liver surgery - Results of the first 100 patients using the Robotic Harmonic curved shears
Authors: Fukumori Daisuke , Tschuor Christoph , Penninga Luit , Hillingsø Jens , Svendsen Lars Bo , Larsen Peter Nørgaard 
Published: October 2023

Aim: Robotic liver surgery (RLS) is a feasible and safe procedure. However, limitations of the robotic instruments used for liver parenchyma dissection compared to laparoscopic and open approaches are major drawbacks of RLS. There is no established technique for liver parenchymal dissection in RLS. The aim of this study is to discuss the surgical outcomes of Totally RLS using Robotic Harmonic curve shears at the University Hospital of Copenhagen, Denmark.
Methods: Between June 2019 and June 2022, RLS was performed with 100 patients. Patient variables and short-term outcomes were retrospectively analysed.
Results: The mean patient age was 63.1 years; the median operating time was 246 min; and the median estimated blood loss was 100 mL. Thirty-two patients underwent subsegmentectomy, 18 mono-segmentectomies, 25 bi-segmentectomies, and 25 major hepatectomies. One patient (1.0%) required conversion to open surgery. Five patients experienced postoperative major complications (Clavien-Dindo classification ≥ IIIa) while no mortalities occurred. Median length of hospital stay was 3 days. There were no significant differences between minor and major hepatectomies in any of the factors.
Conclusion: Based on our study of minor and major hepatectomies in Totally RLS, we conclude that the use of the Robotic Harmonic curve shear for liver parenchyma dissection is feasible and safe.
Considering Mobility Status and Home Environment in Readmission Risk After Total Knee Arthroplasty
Authors: Johnson Joshua K. , Pasqualini Ignacio , Tidd Joshua , Klika Alison K. , Jones Gabrielle , Piuzzi Nicolas S. 
Published: October 2023

Background:
Discharge disposition following total knee arthroplasty (TKA) offers varying levels of post-acute care monitoring depending on the medical status of the patient and his or her ability to function independently. Discharge disposition following TKA is associated with 30-day and 90-day hospital readmission, but prior studies have not consistently considered confounding due to mobility status after TKA, available caregiver support, and measures of home area deprivation. The purpose of this study was to examine 30-day and 90-day readmission risk for patients discharged to a skilled nursing facility (SNF) following TKA after controlling specifically for these factors, among other covariates.

Methods:
This was a retrospective cohort study of patients undergoing TKA at any of 11 hospitals in a single, large, academic health-care system between January 2, 2017, and August 31, 2022, who were discharged to an SNF or home health care (HHC). The adjusted relative risk of readmission within 30 and 90 days of discharge to an SNF compared with HHC was estimated using modified Poisson regression models.

Results:
There were 15,212 patients discharged to HHC and 1,721 patients discharged to SNFs. Readmission within 30 days was 7.1% among patients discharged to SNFs and 2.4% among patients discharged to HHC; readmission within 90 days was 12.1% for the SNF group and 4.8% for the HHC group. The adjusted relative risk after discharge to an SNF was 1.07 (95% confidence interval [CI], 0.79 to 1.46; p = 0.65) for 30-day readmission and 1.45 (95% CI, 1.16 to 1.82; p < 0.01) for 90-day readmission.

Conclusions:
Discharge to an SNF compared with HHC was independently associated with 90-day readmission, but not with 30-day readmission, after controlling for mobility status after TKA, available caregiver support, and home Area Deprivation Index, among other covariates.

Level of Evidence:
Therapeutic Level III. See Instructions for Authors for a complete description of levels of evidence.
Supplementation of mineral nutrients limits the viral RNA accumulation and systemic spread in Vigna unguiculata infected with Groundnut bud necrosis virus
Authors: Singh Ajeet , Narwal Sneh , Mishra Gyan P , Meena Nand Lal , Maheshwari Chirag , Praveen Shelly 
Published: October 2023

Abstract
Groundnut bud necrosis virus (GBNV), a tripartite ambisense RNA genome containing plant virus fall under the family Bunyaviridae and genus Tospovirus. It infects majorly the crops belonging to the leguminosae and solanaceae families, causing characteristic symptoms such as chlorotic and necrotic spots on the leaves. Previously we reported that GBNV infection cycle induces the necrotic cell death at inoculated site and early senescence at the systemic site in the GBNV inoculated plants. In the current study we tried to understand the effect of macro and micro-nutrient supplementation on the viral disease development during GBNV infection in cowpea plant. We found that supplementation of macro-nutrients P (Phosphorus) and K (Potassium), and micro-nutrient Zn (Zinc) reduced the viral accumulation and inhibits the viral spread to systemic site. Whereas the supplementation of micro-nutrient Mn (Manganese) did not show any effect on disease development. Infected plants showed the chlorotic spots at inoculated site, those turned to necrotic as the infection progressed. Occurrence of oxidative stress was judged by the increased concentration of H2O2 (ROS) both at inoculated and systemic sites. ROS concentration was lower in the plants supplemented with nutrients P, K and Zn than the Mn supplemented and non-supplemented plants. We also we conducted a comparative analysis of antioxidants enzymes activities and examined oxidative stress responsive micro RNAs (miRNAs) along with their corresponding target transcripts in cowpea plants infected with GBNV at both inoculated and systemic sites. Antioxidants enzymes activities such as catalase (CAT), superoxide dismutase (SOD), glutathione reductase (GR) and ascorbate peroxidase (APX), were more induced in the plants supplemented with nutrients P, K and Zn than the supplemented with Mn and non-supplemented plants during viral infection. We also found the up-regulation of miR319 controlling metacaspase, responsible for initiation of cell death and down-regulation of miR398 and mir482 controlling COX-5b (Cytochrome C oxidase subunit 5b) and NBS-LRR genes, respectively in the plants supplemented with nutrients P, K and Zn than the supplemented with Mn and non-supplemented plants. Production of stress signals in plant induced with supplementation of macro and micro-nutrients with reduction in viral symptoms both at inoculation and systemic sites are also discussed.
Antigen-Specific Chemokine Profiles as Biomarkers for Detecting Mycobacterium tuberculosis Infection
Authors: Ren Weicong , Ma Zichun , Li Qiang , Liu Rongmei , Ma Liping , Yao Cong , Shang Yuanyuan , Zhang Xuxia , Gao Mengqiu , Li Shanshan , Pang Yu 
Published: October 2023

Abstract
Background
Latent tuberculosis (TB) infection can progress to active TB, which perpetuates community transmission that undermines global TB control efforts. Clinically, interferon-γ release assays (IGRAs) are commonly used for active TB case detection. However, low IGRA sensitivity rates lead to false-negative results for a high proportion of active TB cases, thus highlighting IGRA ineffectiveness in differentiating MTB-infected individuals from healthy individuals.
Methods
Participants enrolled at Beijing Chest Hospital from May 2020-April 2022 were assigned to healthy control (HC), LTBI, IGRA-positive TB, and IGRA-negative TB groups. Screening cohort MTB antigen-specific blood plasma chemokine concentrations were measured using Luminex xMAP assays then were verified via testing of validation cohort samples.
Results
A total of 302 individuals meeting study inclusion criteria were assigned to screening and validation cohorts. Testing revealed significant differences in blood plasma levels of CXCL9, CXCL10, CXCL16, CXCL21, CCL1, CCL19, CCL27, TNF-α, and IL-4 between IGRA-negative TB and HC groups. Levels of CXCL9, CXCL10, IL-2, and CCL8 biomarkers were predictive for active TB, as reflected by AUC values of ≥ 0.9. CXCL9-based enzyme-linked immunosorbent assay sensitivity and specificity rates were 95.9% (95%CI: 91.7–98.3) and 100.0% (92.7–100.0), respectively. Statistically similar AUC values were obtained for CXCL9 and CXCL9-CXCL10 assays, thus demonstrating that combined analysis of CXCL10 and CXCL9 levels did not improve active TB diagnostic performance.
Conclusion
The MTB antigen stimulation-based CXCL9 assay may compensate for low IGRA diagnostic accuracy when used to diagnose IGRA-negative active TB cases and thus is an accurate and sensitive alternative to IGRAs for detecting MTB infection.
Exploring ESL Teachers’ Experiences about ICT-Based 4Cs Skills: A Phenomenological Study
Authors: Soomro Raja Bahar Khan , Khan Riffat Abbas , Rind Irfan Ahmed 
Published: October 2023

Abstract
This study examines the experiences of university-level English as a Second Language (ESL) teachers in relation to the integration of Information and Communication Technology (ICT)-based 4Cs (communication, collaboration, critical thinking, and creativity) skills in English language teaching and learning. The research aims to explore the impact of 4Cs skills on the teaching and learning process, particularly in the context of ESL education. Through a phenomenological study approach, data have been collected through semi-structured interviews with the five ESL teachers of a public sector university's education department. The recorded semi-structured interviews were transcribed into verbatim form and analyzed thematically to gain insights into the ESL teachers' experiences and perceptions regarding ICT-based 4Cs skills. The phenomenological approach offered a rich and nuanced understanding of the five ESL teachers’ experiences by exploring the subjective meanings they attribute to their lived experiences. The findings provided valuable insights into the experiences of ESL teachers and emphasize the significance of ICT-based 4Cs skills in the 21st century. The results highlight the effectiveness of various teaching techniques in implementing these skills but also identify challenges faced by ESL teachers when teaching ESL learners. Overall, this research underscores the importance of integrating ICT-based 4Cs skills in ESL instruction and contributes to the understanding of their implementation in the field of education.
Posterior plating as an alternative to external fixators in the first stage of treatment of pilon fracture with anteromedial soft tissue injury
Authors: Sabbaghzadeh Amir , Gorji Mona , Rezaiyan Mohammad Sadegh , Gholipour Morteza , abbasi Fatemeh , amani hanieh , amoozadeh Farzad 
Published: October 2023

Abstract

Introduction: Pilon fractures management is a challenge. Orthopedic surgeons should manage fracture and soft tissue injury simultaneously in optimum condition. This study evaluates the outcomes of the management of Pilon fracture in two different approaches.
Materials and methods: 40 patients were included with Pilon fractures Between March 2016 and March 2018. Patients were divided into A and B groups. Group A was operated with the external fixator of the pilon and open reduction and internal fixation (ORIF) of distal fibular in the first stage, and medial plating of the pilon in the second stage. Group B was operated with posterior plating of the pilon and fibular by posterolateral approach at the first stage and medial distal tibia plating in the second stage. The AOFAS score, postoperative satisfaction questionnaire score (MODEMS) score, surgical wound complication, union rate, and operation time were evaluated in 12-month follow-up.
Results: 40 Pilon fractures were evaluated finally. 28 were male and 12 were female. Average time for union was 200 ±10 days in group A, and 215±20 days in group B. The average operation duration in the first stage was 65±10 min in group A and 60± 15 min in group B. The MODEMS score at the end of the first stage in most patients of group A was somewhat dissatisfied(86%) and in group B was somewhat satisfied (84%). This score at the end of the 12-month follow-up in most patients of group A and group B was somewhat satisfied, 85% and 87% respectively. The mean AOFAS score in groups A and B were 87.5 and 89.4 respectively at the end of follow-up. There was no significant difference between the two groups in the union rate and time and duration of the operation. Patients in the posterior plating group were more satisfied during the first stage of surgery but in the long-term follow-up, there was no difference between the two groups.
Conclusion: Most surgeons prefer the two-stage strategy and external fixator usage at the stage one to manage the soft tissue complications in the pilon fractures . Based on the result, Posterior plating may be a substitute for external fixation in the first stage of Pilon fractures management.