bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desafíos éticos de la globalización para la investigación clínica
Authors: I Strusberg 
Published: January 2024

La hiperconectividad iniciada durante el proceso de globalización de los 70’ catalizó la trasformación cuali y cuantitativa de los institutos de investigación hacia la creación de redes de investigadores calificados en el uso de técnicas y tecnologías que se fueron estandarizando y permitieron grandes logros mundiales colaborativos como el Proyecto Genoma Humano. La mejora en la expectativa de vida a lo largo del siglo XX fue consolidándose no solo gracias a la potabilización del agua, la vacunación y medicamentos que cambiaron la historia natural de muchas enfermedades, sino también debido a que las guías éticas en investigación biomédica se fueron encarnando en normas jurídicas de cumplimiento obligatorio en muchas regiones del mundo.
A mediados del siglo XX, tras el juicio a los médicos nazis, se creó el Código de Nuremberg. Esta piedra fundacional de la bioética moderna en investigación prioriza la voluntad y la seguridad de las personas. Sin embargo, ni el Juramento Hipocrático ni el Código de Nuremberg evitaron que médicos y otros miembros de los equipos de salud violaran los derechos humanos en investigaciones clínicas llevadas a cabo a posteriori. Reactivamente se crearon no solo los comités de ética para evaluar y monitorear las investigaciones, sino también sistemas gubernamentales dedicados a la fiscalización de todas las partes involucradas. Se entendió que los comités editoriales de revistas de divulgación científica también compartían la responsabilidad en el proceso de garantizar la confiablidad de los datos científicos.
The interrelationships between a company’s marketing and finances
Authors: Grzegorczyk Wojciech 
Published: January 2024

Marketing is responsible for the relationships between a company and its environment and corporate finance deals with the accumulation of financial resources and their allocation for the company’s purposes. The mutual interrelations between marketing and finance in an enterprise are present at the stage of marketing strategy development, in the course of its implementation and during the evaluation of its effects. All of the company’s marketing decisions have a financial aspect since they involve certain costs and bring in profits in the form of the company’s revenue. To gain a permanent competitive advantage, enterprises must foster cooperation between controlling/management accounting and marketing specialists. This cooperation should involve providing the marketing department with information acquired by analysing the financial reports (balance sheets, profit and loss accounts, cash flow statements) of the company itself and its competitors.
Beyond GAAP: A Case Study Analyzing Non-GAAP Financial Measures and SEC Comment Letters through the Lens of the FASB Conceptual Framework
Authors: Hale Kevin , Wetmiller Rebecca J 
Published: January 2024

ABSTRACT
Non-GAAP financial measures are disclosed by companies to provide information to investors and other stakeholders beyond what is required by traditional GAAP-based financial statements. Although these voluntary non-GAAP measures may provide useful information for decision-making, their limited regulation and standardization may mislead investors. This case exposes students to several aspects of non-GAAP measures. First, students will be able to locate, compare, and analyze differences in GAAP and non-GAAP measures in various disclosure mediums and subsequently describe the benefits and disadvantages in different contexts. Next, using EDGAR, students will be able to locate and discuss specific issues regulators have taken with these disclosures by analyzing SEC comment letters. Finally, students will be able to compare the usefulness of GAAP and non-GAAP measures using the FASB conceptual framework. Overall, this case provides students with an increased understanding of how companies use differential financial disclosures in the broader financial reporting environment.
Una investigación sobre el desarrollo de la primera Orquesta Sinfónica Juvenil de Yucatán
Authors: Bautista Cupul Paulina , Cisneros-Cohernour Edith J. 
Published: January 2024

La Orquesta Sinfónica Juvenil de Yucatán nace por motivación de un grupo de jóvenes del estado, quienes crearon un vínculo emocional que no les permitió ser ajenos a su desarrollo histórico y musical, al cual se le pudo dar seguimiento a través de una investigación cualitativa más amplia relacionada con la implementación del Sistema en Yucatán. Por tanto, el propósito de este artículo es dar a conocer los aspectos que favorecieron su auge y permanencia durante 13 años pese a los cambios en su adscripción institucional, así como los determinantes para su cierre. Para esto, se llevaron a cabo 19 entrevistas en profundidad, revisión documental y observación participante durante los ensayos, conciertos, reuniones y actividades de la agrupación.
Los resultados muestran que antes de su adhesión a la versión yucateca de El Sistema, los jóvenes músicos desarrollaron un liderazgo compartido que los llevó a defender sus ideales frente a las autoridades y durante su adscripción se identificaron cuatro áreas de fortalezas y tres de debilidades. Finalmente, en su última etapa de independencia la orquesta juvenil regresó a la inestabilidad de los servicios necesarios para su funcionamiento, tal como en sus inicios. Se concluye, por tanto, que el vaivén en la adscripción de la orquesta como resultado de los cambios políticos fueron determinantes para su supervivencia, en amalgama con el tipo de liderazgo ejercido por los directores y participantes claves, situación que se vuelve crítica ante la falta de investigaciones sobre los aspectos estructurales para armar una orquesta juvenil y las implicaciones para su desarrollo.
Peningkatan Pemahaman Masyarakat Tentang Pengembangan Community Base Ecoturism di Kecamatan Bandar Negeri Suoh, Kabupaten Lampung Barat
Authors: Wulandari Christine , Bakri Samsul , Yuwono Slamet Budi , Febryano Indra Gumay , Kaskoyo Hari , Herwanti Susni , Erdian Zeda , Fadli Nur Ahmad 
Published: January 2024

Konsep (Community Based Tourism) harus diterapkan dalam pengembangan objek wisata dimana, masyarakat berperan penting dalam mengelola objek wisata tersebut. Proses pengelolaan objek wisata ini terdapat beberapa tahap diantaranya tahap perencanaan, pengelolaan serta dampak bermanfaat dari hasil kegiatan yang dilakukan. Kegiatan Pengabdian Kepada Masyarakat (PKM), dilaksanakan pada tanggal 06 – 07 Juli 2023 ini bertujuan dalam meningkatkan pemahaman masyarakat dalam pengembangan wisata alam berbasis konsep Community Base Ecotourism. Metode yang digunakan pada kegiatan ini menggunakan metode ceramah dan Focus Group Discussion (FGD) yang disampaikan oleh Christine Wulandari, Indra Gumay Febryano, Samsul Bakri, Slamet Budi Yuwono, Susni Herwanti dan Hari Kaskoyo Dosen Jurusan Kehutanan serta Zeda Erdian dan Nur Ahmad Fadli mahasiswa Jurusan Kehutanan Univeristas Lampung. Hasil PKM menunjukan pemahaman masyarakat terkait potensi kemitraan dan peranan BUMDes dalam mendukung wisata berbasis masyarakat, perencanaan sarana dan prasarana dalam pengembangan ekowisata termasuk jasa lingkungannya mengalami peningkatan setelah dipaparkan materi dari tim dosen dan mahasiswa Jurusan Kehutanan. Berdasarkan hasil evaluasi pre-test dan post-test terjadi peningkatan pemahaman tentang Community Base Ecoturism sebesar 1,68% yaitu dari 10,77% menjadi 12,45%.
STUDENTS’ PARAPHRASING ABILITY IN ACADEMIC WRITING; TECHNIQUES AND CHALLENGES
Authors: Ovilia Ririn , Addinna Ainul , Oktoviandry Rifky 
Published: January 2024

In higher education, the demand of research publication is steadily growing. Due to this fact, the skills to write academic paper must be improved as well. One of the foremost skills required in writing academic paper is paraphrasing. This qualitative study investigates the most frequents paraphrasing techniques used by students and their challenges during the paraphrasing process. Thirty students enrolled in Academic Writing class participated in this research. The participants were required to do paraphrasing task, and 8 selected students (4 more proficient students and 4 less proficient students) would be interviewed in regards to their challenges in paraphrasing and how they dealt with such challenge. The result of paraphrasing task unveiled that most strategies used by students were “change to synonym”, “change to active to passive form” and a combination of these two. In regards to the challenges, reading, lexical and syntactic problems are the main challenges addressed by participants.
No correlation found between palpation and ultrasound for evaluation of effusion in the medial femorotibial and femoropatellar joint compartments of horses
Authors: Ruff Jennifer H. , Tufts Sara , Robertson James , Horne Caitlyn , Schnabel Lauren V. , Jacobs Carrie 
Published: January 2024

Abstract

OBJECTIVE
To compare palpation and ultrasound scores of effusion of the medial femorotibial and femoropatellar joints of horses.

ANIMALS
40 horses (80 stifles) were evaluated over a 12-week period.

METHODS
Horses > 1 year of age without history of stifle disease were enrolled from September to December 2022. Palpation of right and left medial femorotibial and femoropatellar joint compartments was performed. Amount of effusion was scored by a board-certified large animal surgeon, a third-year large animal surgery resident, and an equine sports medicine intern. Effusion of right and left medial femorotibial and femoropatellar joints was quantified with ultrasound by a board-certified equine sports medicine and rehabilitation clinician. Amount of effusion on palpation and ultrasound was graded as none-mild (1), moderate (2), or severe (3). A 2-way intraclass correlation coefficient evaluated interrater reliability of palpation scores. The Spearman rank correlation determined association between palpation and ultrasound scores.

RESULTS
Interrater reliability for palpation of effusion was poor between all observers for all joint compartments. No significant correlation was identified between palpation and ultrasound scores for any joint compartment for any observer.

CLINICAL RELEVANCE
Clinicians often rely on palpation of joint effusion as an indication of stifle pathology. We found interrater reliability to be poor for palpation scores, indicating low agreement for palpation of joint effusion between clinicians within our group. No correlation was found between palpation and ultrasound scores for joint effusion, indicating that clinicians should not rely on palpation alone to quantify joint effusion of the medial femorotibial and femoropatellar joints.
Neutrophil extracellular traps (NETs) in aortic stenosis: Comparison of methods for assessment of NETs formation
Authors: Kopiński Piotr , Kopytek Magdalena , Ząbczyk Michał , Undas Anetta , Natorska Joanna 
Published: January 2024

Abstract

Introduction
We previously showed increased neutrophil extracellular traps (NETs) formation (NETosis) in patients with severe aortic stenosis (AS). Our aim was to comprehensively assess NETosis in AS using a relatively simple and appropriate technique. We investigated circulating NETosis markers by ELISA and assessed the potential of blood neutrophils to release NETs by flow cytometry.

Materials and Methods
We enrolled 13 patients aged 66 [Q1–Q3, 60–70] years with severe isolated AS without diabetes, chronic kidney disease, and atrial fibrillation. Nine apparently healthy volunteers of similar sex and age served as controls. Serum concentrations of citrullinated histone H3 (citH3), circulating nucleosomes, myeloperoxidase (MPO), and deoxyribonuclease-1 (DNASE1) were measured using ELISAs. Peripheral blood NET-releasing neutrophils were detected by flow cytometry as MPO/citH3-positive cells.

Results
AS patients compared to controls presented 174% higher concentrations of citH3 (p<0.001), 456% higher nucleosomes (p<0.001), 136% higher MPO (p=0.021) and 19% higher DNASE1 levels (p=0.039), together with 101% elevated percentage of NET-releasing neutrophils assessed by flow cytometry (p=0.003). In AS patients, the proportion of blood NET-releasing neutrophils positively correlated with citH3 (r=0.86, p<0.001) and nucleosome (r=0.58, p=0.041) concentrations but not with MPO or DNASE1. Moreover, we observed a strong association between AS severity, measured as aortic valve area (AVA), and serum citH3 concentrations (r=−0.75, p=0.003), but not the number of NET-releasing neutrophils.

Conclusions
Our study showed increased blood neutrophil potential to release NETs together with increased levels of serum markers of NETos is in severe AS patients. However, we recommend ELISA to assess NETosis in vivo as simpler technique giving more unequivocal results compared to flow cytometry.
Conflict Costs in National and International Business: A Comparative Analysis
Authors: Dirrler Phyllis , Podruzsik Szilard 
Published: January 2024

Abstract
Studies presented the importance of conflict costs. Cultural diversity adds more complexity to working groups, fostering conflict. The aim of this research is to investigate how cultural diversity affects conflict costs, measured in terms of lost time & cost amplifiers. Data was collected through an online survey with 490 respondents for national conflicts and 185 respondents for culturally diverse conflict situations. The differences between the two groups are explored by examining their impact on conflict cost amplifiers and the costs themselves. We found that intercultural diversity increases the number of conflicts per year. However, cultural heterogeneity did not affect conflict intensity, duration or the time spent on cost variables. This research is the first one to investigate the effects of cultural diversity on different facets of conflict costs. The results demonstrate the potential, as well as the need for further research.
Simple Extensions
Authors: Schwarzweller Christoph , Rowińska-Schwarzweller Agnieszka 
Published: January 2024

Summary
In this article we continue the formalization of field theory in Mizar. We introduce simple extensions: an extension E of F is simple if E is generated over F by a single element of E, that is E = F (a) for some a ∈ E. First, we prove that a finite extension E of F is simple if and only if there are only finitely many intermediate fields between E and F [7]. Second, we show that finite extensions of a field F with characteristic 0 are always simple [1]. For this we had to prove, that irreducible polynomials over F have single roots only, which required extending results on divisibility and gcds of polynomials [14], [13] and formal derivation of polynomials [15].
The Use of Seismic Isolators to Improve Building Performance
Authors: Rafik Madi , Abdelhak Bordjiba 
Published: January 2024

Abstract
The use of seismic isolators is a design method that involves inserting a flexible element at the base of the structure to decouple its movement from that of the ground to reduce vulnerability to earthquakes. They also make it possible to reduce the demand for force and deformation on the various structural elements. The aim of this research is to evaluate the contribution of HDRB high damping elastomeric seismic isolators in the reduction of seismic forces. It also consists in comparing the results of the dynamic analysis of the two fixed base structures in frames or frames braced by shear walls with the isolated structure mounted on an HDRB elastomer system and subjected to the same seismic excitation using the SAP 2000 calculation software. The results obtained showed an attenuation in the accelerations, a lengthening of the period, strong reduction in displacements and a reduction in the shearing force at the base of the isolated structure compared to fixed base structures.
Harmonic Response of CFRP Tensegrity System in a Suspen-dome
Authors: Olofin IfeOlorun , Liu Ronggui 
Published: January 2024

Abstract
Wind-induced excitation causes structure to vibrate which leads to instability. This paper focuses on the performance of CFRP tensegrity system in a suspen-dome subjected to wind load by assuming such load as harmonic. A comparison is made with the traditional steel tensegrity system, in order to justify the integrity of CFRP cable application in a suspen-dome system. A finite element software, namely ANSYS, was implemented for the simulation by analyzing a physical model of 4 m span and 0.4 m height. Results show that CFRP tensegrity system has similar performance as steel tensegrity system and can be used as a substitute for steel.
Mono-objective Optimization of Retaining Wall Using Genetic Algorithm
Authors: Boukhatem Ghania , Moufida Moussaoui , Kamel Goudjil , Souhila Rehab Bekkouche 
Published: January 2024

Abstract
This paper examines the importance of geotechnical optimization techniques for soil engineering applications, with a particular emphasis on evaluating geotechnical structures. Due to its prevalence in civil engineering, the complex interplay of geotechnical, structural, and financial considerations necessitates a trial and error approach. The study focuses on design elements, geometric dimensions, and volume considerations in order to highlight the economic viability of reinforced concrete retaining walls. Three code files are created using MATLAB to analyze their impact on active and passive thrusts and, as a result, the structure’s volume. The slope angle, backfill overload, and friction angle are varied. The results demonstrate the effectiveness of using evolutionary algorithms to precisely optimize a single goal and demonstrate that this approach can enhance the design of retaining walls in reinforced concrete. This method demonstrates the ability to improve design procedures in this crucial area, which makes it an invaluable resource for structural engineering researchers and civil engineers.
Experimental Study of the Physico-Chemical Stabilization of a Loess by Sodium Silicate: Case of Southern Algeria
Authors: Bahloul Ouassila , Tebbi Fatima Zohra , Lekouara Laid 
Published: January 2024

Abstract
This study focuses on collapsible soil from hyper-arid regions in the south of Algeria (Zeribet El Oued, Biskra). A physical characterization of the studied soil was performed which revealed that the soil samples are loess. After this, an experimental study was done on the influence of the sodium silicate solution (Na2SiO3) at different doses on the collapse potential (CP) and the microstructure of the material. The microstructure investigation was made through a scanning electron microscope (SEM) observation.The main results of this study show that the treatment of collapsible soil with sodium silicate has led to a significant reduction of the collapse potential, exceeding 87%. An effective treatment is obtained with a sodium silicate solution at the optimal dose of 0.8 mol.L−1. The SEM observations have revealed micro-structural transformations which are correlated to changes to geotechnical behavior.
Hydraulic and Water Quality Simulation in a Drinking Water Supply Network: A Case Study of the Ain Regada Network
Authors: Kherouf Mazouz , Goita Fatoumata 
Published: January 2024

Abstract
To ensure the quantitative and qualitative safety of the drinking water supply to urban and rural areas, drinking water supply network managers are always concerned to improve the quality of the service provided to consumers and the continuity and quality of the water distributed. They are also concerned to ensure better management of all water supply systems. The development of computer software has made network modelling an essential part of the design and management of water supply systems. In this context, this study focuses on the operation of the Ain Regada water supply network. The simulation of the operation of the network in its current state is carried out using Epanet software.
Plastic Waste Sheets Effects on Reclaimed Asphalt Pavement Performances
Authors: Boulemaizet Adel , Boudjellal Khaled , Messaoudi Karima , Bekkouche Souhila Rehab 
Published: January 2024

Abstract
This paper aims to examine physical and mechanical performances of a Reclaimed asphalt pavement (RAP) material reinforced with 5 to 15 mm size sheets of plastic waste. The three types of plastic used in the study are: low density polyethylene (LDPE), high density polyethylene (HDPE) and polyethylene terephthalate (PET) with 1%, 1.5%, and 2% dosage by weight of aggregates.
Obtained Duriez test results testify to a 9% to 30% improvement in moisture resistance for all types of plastic compared to virgin mixture while for LDPE waste plastic type workability test attests an acceptable compaction condition for RAP material with less than 1.5% of waste plastic.
Nevertheless, it has been noticed an increase in void index and compaction difficulties starting from 1.5% dosage, resistance to rutting has also improved with the addition of waste plastic, an improvement in fatigue strength was also observed particularly at 2% dosage.
Reuse of Wastewater and Hydrogeneration: Sustainable Land Division Project
Authors: Cardoso-Gonçalves Jorge , Gonçalves Samuel 
Published: January 2024

Abstract
The present case study - Sustainable Cerrado Subdivision Project in Arouca (Portugal) - proposes the implementation of a design solution that promotes ‘sustainable neighborhoods’, expanding the concept of ‘sustainable homes’. This type of project results from the application of established construction methodologies and innovative solutions, aiming to meet society’s needs with the least possible mobilization of resources (natural, energy, and financial), considering water and energy efficiency as central elements. More specifically, the goal is to reduce the inflows into public wastewater and stormwater drainage systems by changing the consumption habits of the population and collecting rainwater in impermeable areas, as well as treating greywater for non-potable reuse. In water supply systems, there is potential for energy production through microturbines that can harness the energy required for pressure control - hydrogeneration.
Analisis Reaksi Pasar Modal Sebelum Dan Sesudah Pengumuman Tarif Cukai
Authors: Astriawati  , Karuniana Dianta A. Sebayang  , Dicky Iranto  
Published: January 2024

The capital market part of economic activity that is susceptible to being influenced by events. The aim of this research was to analyze the influence of the announcement of excise rates in 2020-2022 on the capital market reaction. The capital market reaction is measured the Abnormal Return and Trading Volume Activity. The research sample is 4 cigarette companies listed on the Indonesian Stock Exchange. This research method is event study. The event window of 5 days before and after the event. The test results show that there is a significant difference in abnormal returns in 2020 and 2022 before and after the announcement of the cigarette excise rate increase. However, there is no difference in abnormal returns in 2021 and trading volume activity in 2020, 2021 and 2022 before and after the announcement of the cigarette excise rate increase.