bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS KEMAMPUAN KOMUNIKASI MATEMATIS MAHASISWA CALON GURU MATEMATIKA PADA PEMBELAJARAN KALKULUS INTEGRAL
Authors: Muchlis Effie Efrida , Priatna Nanang , Herman Tatang , Juandi Dadang 
Published: November 2023

Mahasiswa calon guru matematika yang memiliki peran dan fungsi dalam lingkungan pendidikan dituntut untuk berpikir tingkat tinggi dan melakukan penalaran tingkat tinggi, yang semuanya dapat terwujud dengan memiliki kemampuan dasar dalam mengkomunikasikan ide melalui pengembangan kemampuan berpikir matematis baik terhadap dirinya sendiri maupun kepada orang lain. Penelitian ini bertujuan untuk menganalisis kemampuan komunikasi matematis mahasiswa pada pembelajaran kalkulus integral secara keseluruhan kemampuan mahasiswa, berdasarkan kategori kemampuan, dan berdasarkan kemampuan setiap indikator kemampuan komunikasi matematis mahasiswa. Subjek penelitian ini adalah mahasiswa yang mengambil mata kuliah kalkulus integral pada semester 4 tahun pelajaran 2021/2022 sebanyak 37 mahasiswa program studi pendidikan matematika di salah satu Universitas Negeri di Provinsi Bengkulu. Jenis penelitian ini adalah penelitian deskriptif kualitatif dengan menggunakan teknik purposive sampling. Instrumen dari penelitian ini menggunakan tes kemampuan komunikasi matematis dan wawancara. Hasil penelitian menunjukkan: (1) secara keseluruhan kemampuan komunikasi mahasiswa sebesar 75,44% berada pada kategori baik, (2) berdasarkan kategori kemampuan komunikasi matematis menunjukkan bahwa kategori sangat baik berada pada 88,67%, kategori baik berada pada 73,54%, kategori cukup berada pada 52,59%, dan kategori kurang berada pada 40%. (3) kemampuan komunikasi matematis berdasarkan indikator yakni a) mengkonsilidasi pemikiran (ide/gagasan) secara tertulis berada pada 83,06% dengan kategori sangat baik, b) menafsirkan ide atau konsep matematika dalam bentuk grafik, gambar atau tabel berada pada 78,38% dengan kategori baik, c) mengekpresikan ide matematika dengan tepat berada pada 64,86% dengan kategori baik. Hal ini menunjukkan bahwa kemampuan komunikasi matematis mahasiswa masih belum optimal dan memerlukan perhatian dari praktisi pendidikan.
PENGARUH BEBAN KERJA DAN LINGKUNGAN KERJA FISIK TERHADAP KEPUASAN KERJA KARYAWAN PADA PT. SINAR NIAGA SEJAHTERA KABUPATEN BIMA
Authors: Pratama Bagus Aditya , Kusumayadi Firmansyah 
Published: November 2023

Penelitian ini bertujuan untuk mengetahui pengaruh beban kerja dan lingkungan kerja fisik terhadap kepuasan kerja karyawan pada PT. Sinar Niaga Sejahtera Kabupaten Bima. Penelitian ini dirancang dengan menggunakan jenis penelitian asosiatif dengan mengambil data primer dengan bentuk data kuantitatif. Data kuantitatif tersebut diperoleh dari instument penelitian berupa kuesioner berskala likert. Populasi yang digunakan yaitu seluruh karyawan pada PT.Sinar Niaga Sejahtera Kabupaten Bima sebanyak 31 orang. Dengan 29 karyawan tetap dan 2 karyawan kontrak, sampel dalam penelitian ini adalah sebanyak 31 orang Karyawan pada PT. Sinar Niaga Sejahtera Kabupaten Bima dengan teknik sampling jenuh. Metode pengumpulan data menggunakan observasi, wawancara, kuesioner dan studi pustaka. Teknik analisis data yang terdiri dari uji validitas, uji reliablitas, uji asumsi klasik, regresi linear berganda, koefisien korelasi, uji determinasi, ujit dan uji f. Hasil penelitian menunjukan bahwa beban kerja dan lingkungan kerja fisik berpengaruh signifikan secara simultan terhadap kepuasan kerja karyawan pada PT. Sinar Niaga Sejahtera Kabupaten.Kata Kunci: Beban Kerja, Lingkungan Kerja Fisik, Kepuasan Kerja.
PENGARUH PERSEPSI PELAKU UMKM, SOSIALISASI SAK EMKM TINGKAT PENDIDIKAN DAN PEMAHAMAN AKUNTANSI TERHADAP PELAKU UMKM KOTA BATAM
Authors: Buulolo Artinus , Mulyati Sri , Hamidi Hamidi 
Published: November 2023

Pelaku usaha mikro kecil dan menengah akan meningkatkan transparansi dan akuntabilitas dalam pelaporan keuangan, sehingga dapat mempermudah akses mereka terhadap sumber daya finansial dan membantu dalam pengambilan keputusan bisnis yang lebih baik. Tujuan penelitian ini untuk mengetahui persepsi pelaku UMKM, sosialisasi SAK EMKM, tingkat pendidikan, dan pemahaman akuntansi terhadap pelaku UMKM Kota Batam. Jenis penelitian ini adalah kuantitatif. Populasi penelitian ini adalah pelaku UMKM Kota Batam berjumlah 854 orang. Teknik pengambilan sampel menggunakan rumus Slovin berjumlah 90 responden. Data penelitian diperoleh dengan menggunakan instrumen angket yang telah diuji validitas dan reliabilitas. Pengujian data dianalisis dengan metode regresi linier linier berganda, uji hipotesis t dan uji F. Hasil penelitian hipotesis t menunjukkan bahwa persepsi pelaku UMKM berpengaruh positif dan signifikan, sosialisasi SAK EMKM berpengaruh positif dan signifikan, tingkat pendidikan berpengaruh positif dan signifikan, pemahaman akuntansi berpengaruh negatif dan tidak signifikan. Pengujian simultan menunjukkan bahwa persepsi pelaku UMKM, sosialisasi SAK EMKM, tingkat pendidikan dan pemahaman akuntansi berpengaruh positif dan signifikan terhadap pelaku usaha mikro kecil dan menengah Kota Batam.Kata Kunci: Persepsi Pelaku UMKM, Sosialisasi SAK EMKM, Tingkat Pendidikan, Pemahaman Akuntansi, Pelaku UMKM.
IMPLEMENTASI E-GOVERNMENT PADA LAYANAN RED ROSE DI KECAMATAN RUMBAI KOTA PEKANBARU
Authors: Zubaidah Evi , Lubis Ema Fitri , Andry Hendry , Khadijah Ananda Putri 
Published: November 2023

ABSTRACTThis research examines to see and measure the implementation of the Red Rose service application program both in general in providing all information related to the Rumbai sub-district, and specifically in managing information in the management of land documents in the Rumbai sub-district of Pekanbaru city. management of land documents in the Rumbai Sub-district of Pekanbaru City. The Red Rose service application is utilized for information management related to land documents in Rumbai Sub-district. The research method used is a qualitative approach, descriptive research type, with informant selection techniques using purposive sampling, and data analysis techniques using data reduction, data presentation, and conclusion drawing. From the results and discussion, it is concluded that the implementation of the Red Rose application is quite good because it is considered appropriate and provides changes related to people who do not yet have land ownership certificates given the ease of managing SKT with the application, but there is no community involvement with the use of the application. Furthermore, related to employee resources as operating the Red Rose service application is still very minimal. ABSTRAKTujuan dilaksanakannya penelitian ini adalah untuk melihat dan mengukur pelaksanaan program aplikasi layanan Red Rose baik secara umum dalam memberikan seluruh infomasi terkait kecamatan Rumbai, dan secara khusus dapat mengelola informasi dalam pengelolaan dokumen pertanahan di Kecamatan Rumbai Kota Pekanbaru. Aplikasi layanan Red Rose dimanfaatkan untuk pengelolaan informasi terkait dokumen pertanahan di Kecamatan Rumbai. Metode penelitian yang digunakan adalah pendekatan kualitatif, jenis tipe penelitian deskriptif, dengan tehnik pemilihan informan menggunakan purposive sampling, dan teknis analisis data menggunakan reduksi data, penyajian data, dan penarikan kesimpulan. Dari hasil dan pembahasan diperoleh kesimpulan bahwa Implementasi aplikasi Red Rose cukup baik karena dinilai tepat dan memberikan perubahan terkait masyarakat yang belum mempunyai surat kepemilikan tanah diberikan kemudahan dalam pengurusan SKT dengan aplikasi tersebut, akan tetapi belum adanya keterlibatan masyarakat dengan penggunaan aplikasi tersebut. Selanjutnya terkait dengan sumberdaya pegawai selaku pengoprasian aplikasi layanan Red Rose masih sangat minim.
Study of the length of the anterior base of the skull in children from the Moscow region
Authors: Proskokova S. V. , Pirogov A. E. , Voronetskaya V. A. , Enikeev A. M. , Bogdanova K. M. , Proskokov N. A. 
Published: November 2023

Relevance. One of the starting points for calculating the parameters of growth and the ratio of the jaws is considered to be the sagittal size of the anterior base of the skull. To this day, many orthodontists are guided by the average values of the anterior skull base, found in 1972. This article is devoted to the study of the comparison of the average statistical sagittal dimensions of the length of the anterior skull base in children of the Moscow region aged 4 to 16 years with occlusal ratios according to the first Angle class in 2023 with the data proposed in the studies of Dr. Jarabak in 1972.Objective. To compare the average sagittal dimensions of the length of the anterior base of the skull in children of the Moscow region aged from 4 to 16 years with occlusal ratios for the first Engl class in 2023 with the data proposed in the studies of Dr. Jarabak in 1972.Materials and methods. The study included 331 people aged 4 to 16 years. The sagittal dimensions of the length of the anterior base of the skull were calculated in the digital program for the analysis of CBCT in children with occlusive ratios in the first class of male and female Engl on the digital X-ray machine Planmeca ProMax 3D Max X-ray diagnostic centers «Golden Section».Results. Male patients of the Moscow region approach the lower limits of the growth value of the anterior base of the skull only by the age of 12 and reach the confident values of the norm proposed by Dr. Jarabak only by the age of 16. And female patients in the Moscow region, for the most part, do not reach the limits of the norm proposed by Dr. Jarabak, lagging in values by 2–3 mm in a smaller direction.Conclusion. It is necessary to calculate and develop norms for Russian children, taking into account racial characteristics, environmental conditions, nutritional conditions, physical and social development, which differ significantly, but at the same time strongly affect the growth and formation of skeletal structures.
Serum uric acid levels and risk of cardiovascular disease in type 2 diabetes: results from a cross-sectional study and Mendelian randomization analysis
Authors: He Ying , Feng Jincheng , Zhang Bo , Wu Qiong , Zhou Yongjie , He Diao , Zheng Daofeng , Yang Jiayin 
Published: November 2023

AimsSerum uric acid (SUA) levels have been previously linked to a higher risk of cardiovascular disease (CVD) in individuals with type 2 diabetes (T2D) according to various observational studies. However, whether this association is causally linked or simply influenced by confounding factors is unclear. Therefore, this study utilized Mendelian randomization (MR) analysis to explore the causality between SUA levels and the risk of CVD in individuals with T2D.MethodsOur study cohort consisted of 5723 participants who were diagnosed with T2D in the National Health and Nutrition Examination Survey (NHANES) from 1999-2018. The study assessed the association between SUA levels and the risk of CVD using a multivariable logistic regression model. To further examine causality between SUA levels and CVD, a two-sample MR study was conducted utilizing genetic data from genome-wide association studies (GWAS) involving over 140,000 individuals. The main MR analysis employed the inverse-variance-weighted (IVW) method. Additionally, several sensitivity analyses were performed to evaluate the robustness and pleiotropy of the results.ResultsIn the cross-sectional study, after multivariable adjustment, participants with SUA levels &gt;6.7 mg/dL exhibited odds ratios (ORs) of 1.51 (95% CI: 1.01-2.26, p=0.049) for heart failure, 1.02 (95% CI: 0.69-1.50, p=0.937) for coronary heart disease, 1.36 (95% CI: 0.78-2.38, p=0.285) for angina, and 1.22 (95% CI: 0.80-1.85, p=0.355) for myocardial infarction when compared to participants with SUA levels ≤ 4.6 mg/dL. However, in the IVW analysis, no causality between SUA levels and the risk of heart failure was observed (OR = 1.03, 95% CI: 0.97-1.09, p = 0.293). The secondary analysis yielded similar results (OR = 1.05, 95% CI: 0.96-1.14, p = 0.299). The sensitivity analyses further supported our primary findings.ConclusionBased on the MR study, we did not find supporting evidence for a causal association between SUA levels and the risk of heart failure.
Detailed findings of videofluoroscopic examination among patients with Parkinson's disease on the effect of cervical percutaneous interferential current stimulation
Authors: Nakamori Masahiro , Toko Megumi , Yamada Hidetada , Hayashi Yuki , Haruta Azusa , Hiraoka Aya , Yoshikawa Mineka , Nagasaki Toshikazu , Ushio Kai , Yoshikawa Kohei , Shimizu Yoshitaka , Mikami Yukio , Maruyama Hirofumi 
Published: November 2023

IntroductionParkinson's disease (PD) leads to various types of swallowing disorders. We investigated the effect of cervical percutaneous interferential current stimulation on dysphagia. By conducting detailed qualitative and quantitative analysis of videofluoroscopic examination, we aimed to understand dysphagia in patients with PD and investigate its effects on swallowing function.MethodsPatients received cervical percutaneous interferential current stimulation for 20 min twice a week for 8 weeks. In this exploratory study, we evaluated aspiration/laryngeal penetration, oral cavity residue, vallecular residue, and pharyngeal residue. In addition, we performed temporal analysis.ResultsTwenty-five patients were completely evaluated. At baseline, the proportions of laryngeal penetration/aspiration, oral cavity residue, epiglottic vallecula residue, and pharyngeal residue were 40.0, 88.0, 72.0, 60.0, and 16.0%, respectively. Conversely, pharyngeal transit time, laryngeal elevation delay time, pharyngeal delay time, and swallowing reflex delay were nearly within the normal ranges. Cervical percutaneous interferential current sensory stimulation improved only oral cavity residue at the end of the intervention, from 88.0 to 56.0%.DiscussionPatients with PD demonstrated remarkably high frequencies of residues in the oral and pharyngeal regions. The usefulness of cervical interferential current stimulation was partially demonstrated for oral cavity residue. Considering that PD exhibits diverse symptoms, further accumulation of cases and knowledge is warranted.Trial registrationjRCTs062220013.
MiR-124-3p mediates gastric cancer cell ferroptosis induced by an anti-cancer drug polyphyllin I
Authors: Zheng Fang , Bi Jian-Can , Wei Yu-Yan , Wang Yeshu , Zhang Qunfang , Liang Chun-Ling , Wu Jianwei , Dai Zhenhua 
Published: November 2023

Background: Ferroptosis is an emerging type of regulated cell death and associated with antitumoral therapy, while some microRNAs have been shown to regulate the tumorigenesis and cancer progression. Meanwhile, polyphyllin I (PPI) has exhibited antitumoral effects by promoting cancer cell apoptosis and ferroptosis. However, it is unclear whether PPI induces cancer cell ferroptosis by regulating microRNAs.Methods: We used two gastric cancer cell lines (AGS and MKN-45) to set up a tumor model of the nude mice, which were then treated daily with PPI to measure the cancer growth in vitro and in vivo. Ferroptosis was measured using immunofluorescence staining and flow cytometric analysis according to levels of intracellular ROS, lipid ROS and ferrous ions. Moreover, NRF2 expression was measured by Western blotting. In some experiments, the mimics or inhibitors of miR-124-3p were used to further confirm its involvement in PPI-induced cancer cell ferroptosis.Results: Here we found that miR-124-3p mediated cancer ferroptosis and tumor repression induced by PPI since PPI increased miR-124-3p expression in gastric cancer cells and promoted their ferroptosis, whereas inhibition of miR-124-3p mostly abolished the effects of PPI on tumor growth, ferroptosis and NRF2 expression. Moreover, miR-124-3p mimics promoted cancer cell ferroptosis by downregulating NRF2 through directly targeting 3′-UTR region of NRF2, confirming a role for miR-124-3p in regulating PPI-induced ferroptosis.Conclusion: PPI exerts its antitumoral effects on the gastric cancer by promoting cell ferroptosis via regulating miR-124-3p. Our findings have clinical implications for cancer chemotherapy.
Correlates of intimate relationship satisfaction among investigators of child sexual abuse material
Authors: Gewirtz-Meydan Ateret , O'Brien Jennifer E. , Mitchell Kimberly J. 
Published: November 2023

IntroductionThis study investigates correlates of intimate relationship satisfaction among investigators of child sexual abuse material (CSAM). Previous research has shown that exposure to CSAM content can negatively impact investigators’ emotional wellbeing, but little is known about its association with their intimate relationships.MethodsThe study included 500 participants who were police investigators, forensic examiners, and other professionals connected with the criminal justice system in the United States that are exposed to CSAM as part of their profession. The study collected data through an anonymous survey administered via the Qualtrics online survey system.ResultsThe findings reveal that higher levels of depressive symptoms and post-traumatic stress disorder are associated with lower relationship satisfaction among CSAM investigators. Additionally, group connectedness is positively related to relationship satisfaction for both men and women. Parent investigators also reported lower relationship satisfaction, suggesting unique challenges faced by this subgroup. Exposure to varying types of CSAM content was not significantly related to lower relationship satisfaction. This study highlights the association between depressive symptoms and PTSD with relationship satisfaction among CSAM investigators, emphasizing the role of group connectedness in promoting positive outcomes for both male and female investigators.DiscussionRecognizing the association between depressive symptoms and PTSD with relationship satisfaction can guide interventions and support services for investigators, promoting group connectedness and addressing mental health concerns to enhance resilience and effectiveness in combating child exploitation.
Decamethoxin and chlorhexidine bigluconate effect on the adhesive and biofilm-forming properties of Streptococcus mitis
Authors: Faustova Mariia O. , Chumak Yuliia V. , Loban’ Galina A. , Ananieva Maiia M. , Havryliev Viktor M. 
Published: November 2023

The aim of the studyWas to investigate the effect of antiseptics on the adhesive and biofilm-forming properties of clinical S.mitis isolates isolated from the oral cavity of patients with an infectious and inflammatory post-extraction complication.Materials and methodsTwenty four clinical isolates of S.mitis isolated from patients were studied. The studied antiseptics included 0.02% aqueous solution of decamethoxin and 0.05% solution of chlorhexidine bigluconate. Adhesion of clinical isolates under the action of decamethoxin and chlorhexidine bigluconate was determined by the method of V.I. Brillis. The biofilm-forming properties of clinical isolates were studied using the “microtiter plate test” according to G.D. Christensen.ResultsThe studied clinical isolates of S.mitis are classified as highly adherent microorganisms. Action of decamethoxin on clinical isolates decreases the adhesion index of the studied isolates in comparison with the adhesion index of the control culture. Action of chlorhexidine bigluconate on S.mitis isolates increases of adhession of the studied clinical isolates in comparison with the control. After the effect of decamethoxin, the optical density of clinical isolates decreased considering the optical density results of the control. The clinical isolates left an average film-forming capacity even after chlorhexidine bigluconate action.ConclusionsClinical isolates of S.mitis are highly adherent microorganisms. The antiseptic decamethoxin decreases the adhesion index of these bacteria, while chlorhexidine bigluconate increases the adhesion index of clinical S.mitis isolates. Clinical S. mitis isolates have an average biofilm formation capacity index. The antiseptic decamethoxin inhibits the biofilm formation capacity of S.mitis from medium to low.
A Decade of Experience With Alemtuzumab Therapy for Severe or Glucocorticoid-Resistant Kidney Transplant Rejection
Authors: van Vugt Lukas K. , van der Zwan Marieke , Clahsen-van Groningen Marian C. , van Agteren Madelon , Hullegie-Peelen Daphne M. , De Winter Brenda C. M. , Reinders Marlies E. J. , Miranda Afonso Pedro , Hesselink Dennis A. 
Published: November 2023

Alemtuzumab is used as lymphocyte-depleting therapy for severe or glucocorticoid-resistant kidney transplant rejection. However, the long-term efficacy and toxicity of alemtuzumab therapy are unclear. Therefore, all cases of alemtuzumab anti-rejection therapy between 2012 and 2022 in our institution were investigated. Graft survival, graft function, lymphocyte depletion, serious infections, malignancies, and patient survival were analyzed and compared with a reference cohort of transplanted patients who did not require alemtuzumab anti-rejection therapy. A total of 225 patients treated with alemtuzumab were identified and compared with a reference cohort of 1,668 patients. Over 60% of grafts was salvaged with alemtuzumab therapy, but graft survival was significantly poorer compared to the reference cohort. The median time of profound T- and B lymphocyte depletion was 272 and 344 days, respectively. Serious infection rate after alemtuzumab therapy was 54.1/100 person-years. The risk of death (hazard ratio 1.75, 95%-CI 1.28–2.39) and infection-related death (hazard ratio 2.36, 95%-CI 1.35–4.11) were higher in the alemtuzumab-treated cohort. In conclusion, alemtuzumab is an effective treatment for severe kidney transplant rejection, but causes long-lasting lymphocyte depletion and is associated with frequent infections and worse patient survival outcomes.