bluuebunny/crossref_metadata_2025_split huggingface dataset:
Decoding the aroma of Rosa canina L.: Chemical composition and gene expression
Authors: Jariani Parisa , Shahnejat-Bushehri Ali-Akbar , Naderi Roohangiz , Zargar Meisam , Naghavi Mohammad Reza 
Published: January 2025

Objective
The aromatic profile of Rosa canina L. petals hold immense potential for the fragrance and pharmaceutical industries. This study aims to investigate the chemical composition and gene expression patterns across different floral development stages to uncover the biosynthetic pathways of floral scent.

Methods
Essential oils (EOs) were extracted from petals at five developmental stages (S1-S5) and analyzed using Gas Chromatography-Mass Spectrometry (GC-MS), identifying 20 distinct compounds. RNA isolation and quantitative real-time PCR (qRT-PCR) analysis were performed to assess gene expression.

Results
Stage S3, notable for its enhanced aromatic profile, was dominated by terpenoid compounds such as β-Citronellol (1.18%), Caryophyllene (8.59%), β-Selinene (1.50%), and Caryophyllene oxide (0.50%), indicating significant upregulation of terpenoid biosynthesis genes. qRT-PCR analysis revealed that CCD1 had the highest expression in S4 (9.51-fold), while DXR and DXS peaked at S3 with fold changes of 29058.38 and 73.35, respectively. Other genes like AAT1, LIS, and GPS also showed peak expressions at S3 with fold changes of 1.33, 10.70, and 1.18, respectively. PAR exhibited the highest expression in S1, while GGPPS peaked in S4 (2.01-fold). Clustering analysis indicated distinct groupings of developmental stages and gene expression patterns, with strong correlations between specific genes and compounds, such as CCD1 with GGPPS (0.78) and β-Citronellol with Caryophyllene (0.92). Principal Component Analysis (PCA) highlighted significant contributions of AAT1, GPS, and nonadecane compounds to the overall variance.

Conclusion
These findings provide a comprehensive understanding of the chemical and genetic factors shaping the aromatic profile of R. canina, with promising applications for both the fragrance and pharmaceutical sectors. The study’s innovation lies in the detailed correlation between EO composition and gene expression, presenting new insights into the biosynthetic pathways of floral scent.
High-flow nasal cannula for pre- and apneic oxygenation during rapid sequence induction intubation in emergency surgery: A systematic review and meta-analysis
Authors: Tang Hong , Yang Yanyan , Li Hong 
Published: January 2025

Background
Rapid sequence induction intubation (RSII) is commonly used in emergency surgeries for patients at high risk of aspiration. However, these patients are more susceptible to hypoxemia during the RSII process. High-flow nasal cannula (HFNC) oxygen therapy has emerged as a potential alternative to traditional face mask (FM) ventilation pre- and apneic oxygenation. This meta-analysis aimed to evaluate the efficacy of HFNC compared to FM during RSII in emergency surgeries.

Methods
We conducted a comprehensive literature search across PubMed-MEDLINE, EMBASE-OVID, Scopus, and Web of Science databases up to July 20, 2024. Randomized controlled trials comparing HFNC with FM during RSII for emergency surgery patients were included. The primary outcomes were post-intubation arterial partial pressures of oxygen (PaO2) and carbon dioxide (PaCO2). Secondary outcomes included post-intubation end-tidal carbon dioxide concentration (EtCO2), incidence of desaturation, apnea time, lowest peripheral oxygen saturation (Lowest SpO2), and occurrence of regurgitant aspiration. We used the GRADE approach to assess the certainty of evidence and the Cochrane Risk of Bias 2 (RoB 2) tool to evaluate risk of bias.

Findings
This meta-analysis encompassed six studies, involving a total of 703 patients. HFNC oxygen therapy demonstrated a significant increase in post-intubation arterial PaO2 compared to FM (mean difference = 63.02 mmHg, 95% CI: 8.99 to 117.05, p = 0.02), while no significant difference was observed in arterial PaCO2. Moreover, HFNC substantially prolonged apnea time (mean difference = 19.25 seconds, 95% CI: 1.69 to 36.82, p = 0.03). No statistically significant differences were found between HFNC and FM regarding EtCO2, incidence of desaturation, Lowest SpO2, or regurgitant aspiration.

Conclusion
This systematic review and meta-analysis indicates that HFNC may be superior to FM for pre-oxygenation and apneic oxygenation during RSII in emergency surgeries, particularly in improving oxygenation. While these findings are promising, further high-quality research is necessary to establish definitive guidelines for HFNC use in this context.
The corneal biomechanical changes of phacoemulsification in cataract patients: A systematic review and meta-analysis
Authors: Li Xinru , Li Xiaofeng , Tan Lintong , Chen Hu , Lai Yuan 
Published: January 2025

Purpose
To evaluate the corneal biomechanical properties of phacoemulsification in the treatment of cataract patients.

Methods
Pertinent studies were searched in PubMed, EMBASE, Web of Science and clinicaltrials.gov., as of November 05, 2024. The reference lists of related published reviews were included as well. This meta-analysis was performed with Stata Software and Review Manager, we used mean difference (MD) to evaluate the statistical consequence, using I2 statistic to assess the heterogeneity. Subgroup analysis were performed under the occurrences of high heterogeneity. We used eleven items to describe the characteristics of included studies, publication bias was performed with Egger’s test. The quality assessment were evaluated with 3 items by Newcastle-Ottawa Scale (NOS) items.

Results
Thirteen eligible studies were identified for data synthesis and assessment. According to the result of meta-analysis, the central corneal thickness(CCT) (MD = 10.50, 95% CI: [5.01, 15.98]; P<0.05) and intraocular pressure(IOPg)(MD = -0.73, 95% CI: [-1.26, -0.19]; P<0.05) of cataract patients after phacoemulsification was significantly higher than the control groups. The values of corneal hysteresis(CH) (MD = -0.43, 95% CI: [-0.62, -0.23]; P<0.05) and corneal resistance factor(CRF) (MD = -0.49, 95% CI: [-0.64, -0.33]; P<0.05) after phacoemulsification surgery were statistically lower than the control groups. While the values of IOPcc did not show statistically different (MD = -0.13, 95% CI: [-0.67, 0.41]; P = 0.64).

Conclusion
Included data analysis indicated that the values of CCT, CH, CRF and IOPg showed statistical change in cataract patients after phacoemulsification surgeries compared with control groups. There is a correlation between corneal biomechanics and phacoemulsification surgeries.
Phase angle in bioelectrical impedance analysis for assessing congestion in acute heart failure
Authors: Sohn Sangho , Jeon Jinsung , Lee Ji Eun , Park Soo Hyung , Kang Dong Oh , Park Eun Jin , Lee Dae-In , Choi Jah Yeon , Roh Seung Young , Na Jin Oh , Choi Cheol Ung , Kim Jin Won , Rha Seung Woon , Park Chang Gyu , Lee Sunki , Kim Eung Ju 
Published: January 2025

Background
The phase angle (PhA) in bioelectrical impedance analysis (BIA) reflects the cell membrane integrity or body fluid equilibrium. We examined how the PhA aligns with previously known markers of acute heart failure (HF) and assessed its value as a screening tool.

Methods
PhA was measured in 50 patients with HF and 20 non-HF controls along with the edema index (EI), another BIA parameter suggestive of edema. Chest computed tomography-measured lung fluid content (LFC) was used to assess pulmonary congestion. A correlation analysis was conducted to evaluate the relationships between PhA and EI, NT-proBNP, and LFC. Receiver operating characteristic (ROC) curve analysis was used to determine the cut-off values for PhA and EI for classifying patients with HF. The area under the curve (AUC) was compared using the DeLong test to evaluate the performance of PhA and EI compared to that of LFC in correctly classifying HF.

Results
The PhA levels were significantly lower in the HF group. Whole-body PhA was 4.49° in the HF group and 5.68° in the control group. Moderate and significant correlation was observed between PhA measured at 50-kHz and both NT-proBNP (-0.56 to -0.27, all p-values<0.05) and LFC (-0.52 to -0.41, all p-values <0.05). The AUC for whole-body PhA was 0.827 (confidence interval [CI] 0.724–0.931, p<0.01) and was 0.883 (CI 0.806–0.961, p<0.01) for EI, and the optimal cutoffs were estimated as 5° (sensitivity 0.84, specificity 0.80) and 0.394 (sensitivity 0.78, specificity 0.95), respectively. When both PhA and EI were included in the model, the AUC increased to 0.905, and this was comparable to that of LFC (AUC = 0.913, p = 0.857).

Conclusions
PhA exhibited a correlation with known markers of HF and demonstrated its potential as a non-invasive screening tool for the early detection of HF exacerbation. The combined use of PhA and EI can provide a robust alternative for routine self-monitoring in patients with HF, thereby enhancing early intervention.
Exploring the dynamics of self-efficacy, resilience, and self-management on quality of life in type 2 diabetes patients: A moderated mediation approach from a positive psychology perspective
Authors: Ting Zheng , Huicai Wang , Kudelati Zakeer , Yongkang Ge , Alimu Ayimire , Xiaotian Zhang , Xingge Qu , Tong Li 
Published: January 2025

Objectives
Type 2 diabetes mellitus (T2DM) significantly deteriorates patients’ quality of life (QOL). This study examined the dynamic interplay of factors that influence QOL in patients with T2DM, utilizing concepts from positive psychology and intrinsic mechanisms, to lay the groundwork for improving patient outcomes. Improving self-management behaviors is essential for effective disease management.

Methods
Using a cross-sectional design, this study incorporated 408 patients with T2DM from the endocrinology department of a public hospital in Urumqi, who were selected through convenience sampling from December 29, 2023 to June 30, 2024. Data collection tools included the General Data Questionnaire, Summary of Diabetes Self-Care Activities, Self-Efficacy for Diabetes Questionnaire, Connor-Davidson Resilience Scale, and Diabetes-Specific Quality of Life Scale. Structural equation modeling and Model 15 of Hayes’ SPSS-Process program facilitated the moderated mediation analysis.

Results
The findings demonstrated that self-efficacy significantly enhanced the QOL (β = -0.8557, p < 0.01), with resilience serving as a partial mediator, accounting for 43.1% of this effect. Interactions between self-efficacy and self-management, and resilience and self-management, were also significant predictors of QOL (β = -0.0751, p < 0.01 and β = -0.0073, p < 0.05, respectively).

Conclusion
These findings introduce a novel theoretical framework for T2DM from the perspective of positive psychology, which will be beneficial for intervention development. This study underscores the importance of promoting diabetes self-management as an effective strategy to enhance QOL. Additionally, healthcare providers must focus on fostering patients’ positive psychological traits and reliable self-management behaviors.
The efficacy of acupuncture in relieving postoperative pain in patients with low simple anal fistula: Protocol of a prospective, randomised, controlled trial
Authors: Yang Min , Zheng De , Jin Xingtao , Tang Huili , Cao Weiwei , Ye Qianqian , Qu Yin , Mei Zubing 
Published: January 2025

Background
Anal fistula surgery often leads to postoperative pain, which can hinder recovery and negatively impact patients’ quality of life. This prospective, randomised, controlled trial (RCT) aims to investigate the efficacy of acupuncture in alleviating postoperative pain and reducing the usage of analgesic medications following anal fistula surgery.

Methods
This single-centre, patient-blinded, assessor-blinded, placebo-controlled randomised controlled trial (RCT) will be conducted at a tertiary referral hospital. A total of 66 patients with low simple anal fistula will be randomised at a 1:1 ratio to receive either acupuncture or sham acupuncture. The primary outcome is the difference in the numerical rating scale (NRS) pain score before and after acupuncture at 6 hours post surgery. The secondary outcomes include postoperative analgesic usage (Day 0 to Day 7), complications (including infection, urinary retention, and bleeding from Day 0 to Day 7, as well as delayed wound healing and recurrence within 3 months post surgery), sleep quality (PSQI from Day 0 to Day 7), psychological state (SDS and SAS on Day 0, Day 1, and Day 7), and overall recovery quality (QoR-15 on Day 1, Day 3, and Day 7). The statistical analysis of this trial will be conducted using SPSS software, validating the normality of data and the homogeneity of variance, and employing t-tests, Mann-Whitney U tests, chi-square tests, and repeated measures ANOVA to analyze baseline data, primary and secondary outcome indicators.

Discussion
This study aims to contribute to the expanding evidence base regarding the role of acupuncture in postoperative pain management. Through a comprehensive assessment of pain relief, analgesic usage, and other recovery-related outcomes, our findings will establish a foundation for standardizing acupuncture protocols specifically tailored for anal fistula surgery patients. The strengths of this trial are rooted in its rigorous randomised controlled trial (RCT) design, comprehensive outcome measures, and focused examination of a clinically significant issue. Ultimately, the findings of this trial have the potential to offer valuable insights into the utility of acupuncture as an adjunctive therapy for postoperative pain management among anal fistula patients, thereby informing future clinical practice and research directions.

Trial registration
This study was registered in the China Clinical Trial Registry on June 1, 2024, with registration number: ChiCTR2400085178.
Quo Vadis?, Cabiria and the ‘Archaeologists’: Early Italian Cinema’s Appropriation of Art and Archaeology, Ivo Blom (2023)
Authors: Pieraccini Lisa 
Published: January 2025

Review of: Quo Vadis?, Cabiria and the ‘Archaeologists’: Early Italian Cinema’s Appropriation of Art and Archaeology, Ivo Blom (2023)
Turin: Edizione Kaplan, 312 pp.,
ISBN 978-8-89955-966-3, p/bk, €40.00
Italian Americans in Film: Establishing and Challenging Italian American Identities, Daniele Fioretti and Fulvio Orsitto (eds) (2023)
Authors: Tamburri Anthony Julian 
Published: January 2025

Review of: Italian Americans in Film: Establishing and Challenging Italian American Identities, Daniele Fioretti and Fulvio Orsitto (eds) (2023)
Cham: Palgrave Macmillan, 309 pp.,
ISBN 978-3-03106-464-7, p/bk, $149.17
Explorando el territorio desde la educación ambiental comunitaria
Authors: Hernández Barbosa Rubinsten , Sanabria Quira Alejandra , Pedraza Jimenez Yamile 
Published: January 2025

Se realizó un análisis documental, de carácter exploratorio, a partir de los informes de investigación, con categorías previamente establecidas que permitieron responder a la pregunta ¿Cuáles metodologías y elementos conceptuales de la Educación Ambiental Comunitaria se ponen de manifiesto en los proyectos desarrollados por el Grupo de Investigación MICRAM? Se desarrolló en cinco (5) etapas, para cada una de éstas se estableció un objetivo. El análisis de los resultados de los informes, permite anotar que la Educación Ambiental Comunitaria, además de la participación activa de los individuos y comunidades, requiere que se plantee más allá de aspectos curriculares de los sistemas educativos estandarizados, que responda de manera armónica a consolidar ideales y valores desde otras cosmovisiones, ayuda a develar formas de ser, estar, hacer, interactuar, reconocerse, proyectarse y transformarse de las comunidades.
Chimeric Antigen Receptor T-Cell-Associated Cholangiopathy: First Reported Case of a Complication of Chimeric Antigen Receptor T-Cell Therapy
Authors: Huang Albert Z. , Kim Hyun Jae , Zhao Billy , Owen Daniel R. , Jain Avni , Chahal Daljeet , Yoshida Eric M. 
Published: January 2025

ABSTRACT
Chimeric antigen receptor T-cell (CAR-T) therapy is a novel immunotherapy for the treatment of refractory malignancies. While various complications have been described previously, sclerosing cholangitis has not been reported. We report the first description of sclerosing cholangitis secondary to Tecartus CAR-T therapy in a 67-year-old man with refractory stage IV mantle cell lymphoma. As CAR-T therapy becomes increasingly used in clinical practice, it is critical to recognize potential hepatobiliary complications. Further research is needed to facilitate early diagnosis and to develop effective treatment strategies for managing these rare but severe complications.
Novo ensino médio e o “cidadão” como consumidor
Authors: Costa Erick 
Published: January 2025

Resumo: O presente artigo pretende salientar os traços pragmáticos presentes na reforma do ensino médio e sua tentativa de desenvolver uma formação que contemple mais os interesses e projetos de vida dos alunos. Defendemos que a reforma visa atender demandas típicas do cidadão como consumidor tal como caracterizado pelo sociólogo Wolfgang Streeck. O Novo Ensino Médio pode ser visto como uma tentativa de tornar a educação mais atrativa em meio a uma sociedade pautada pela lógica de consumo. Discorremos sobre os riscos de se pensar a educação sob a ótica do utilitarismo e do investimento pessoal, sobre o caráter pragmático e a-histórico de uma educação orientada pelo desenvolvimento de competências, bem como sobre a necessidade de formar pessoas responsáveis e comprometidas com o mundo.
Palavras-chave: Educação; Reforma; Cidadania; Consumidor.
New High School and the “citizen” as consumer
Abstract: The present article intends to emphasize the pragmatic traits present in the High school reform and its attempt to develop a kind of training that includes more of the students interests and life projects. We defend that this reform aims to meet typical demands of the citizen as a consumer, as characterized by the sociologist Wolfgang Streeck. The new High school may be seen as an attempt to make education more attractive in a society guided by the logic of consumption. We discuss the risks of thinking education from the perspective of pragmatism and personal investment, about the pragmatic and non-historical character of an education guided by the competence development, as well as about the necessity of forming responsible people and committed with the world.
Keywords: Education; Reform; Citizenship; Consumption.
Nouvel Enseignement Secondaire et le « citoyen » en tant que consommateur
Résumé: Cet article met en évidence les aspects pratiques de la réforme de l'enseignement secondaire et son objectif de fournir une formation qui tienne davantage compte des intérêts et des projets de vie des élèves. Nous soutenons que cette réforme cherche à répondre aux attentes communes du citoyen en tant que consommateur, telles qu'identifiées par le sociologue Wolfgang Streeck. Le nouvel enseignement secondaire peut être considéré comme une tentative de rendre l'éducation plus attrayante dans une société guidée par la logique de la consommation. Nous abordons les risques associés à la perception utilitaire de l'éducation et de l'investissement personnel, ainsi que le caractère pragmatique et sans référence historique d'une éducation centrée sur le développement des compétences. Nous soulignons également l'importance de former des individus responsables et engagés dans le monde.
Mots-clés: Éducation; Réforme; Citoyenneté; Consommateur.

Data de registro: 13/01/2024
Data de aceite: 30/10/2024
A comprehensive review on impact of climatic change on adaptability and mitigation in fruit crop
Authors: Sundarrajan R V , Rajangam J , Saraswathy S , Gnanasekaran M , Rajesh S , Anitha T , Muthuramalingam S , Sankar C 
Published: January 2025

Global warming and climate change are among the most pressing challenges confronting humanity in the 21st century. Climate change will result in rising temperatures, changes in rainfall patterns and an increased occurrence of extreme weather events, such as heatwaves, cold spells, frost days, droughts and floods. The effects of climate change have recently become more evident, with rising temperatures, altered and irregular precipitation patterns and increased extreme weather events. These changes are directly impacting the maturity and development of fruit crops. Heat stress during flowering and fruit set can greatly reduce fruit production, while irregular rainfall may disrupt pollination and heighten the risk of pests and diseases. Furthermore, increased carbon dioxide levels can influence the quality characteristics of fruits. To maintain the ongoing production and sustainability of fruit crops, it is vital to enhance resilience. Focusing on developing new varieties that offer higher yield potential and resistance to various stresses, such as drought, flooding and salinity, is crucial for sustaining crop yields. Additionally, breeding programs should aim to enhance the germplasm of key tropical and subtropical fruit crops to improve heat stress tolerance. Recent advancements in genetic editing technologies present substantial opportunities for the agricultural sector, especially in enhancing fruit crop traits. These innovations can be precisely tailored to meet consumer preferences, which is crucial for driving commercial success. In this review, we strive to provide a comprehensive overview of the current understanding of this important topic, along with recommendations for future research.
Incompressible limit for the compressible viscoelastic fluids in critical space
Authors: Han Bin , Wu Dan 
Published: January 2025

Abstract
In this article, we consider the incompressible limit of global-in-time strong solutions with arbitrary large initial velocity for the compressible viscoelastic fluids in the sense of critical Besov framework. We decouple our compressible system into two coupling sub-systems by introducing a skew symmetric matrix, which is related to the deformation tensor. This work generalizes the similar result obtained by Hu et al. (Incompressible limit for compressible viscoelastic flows with large velocity, Advances in Nonlinear Analysis 12 (2023), 20220324) to the critical functional space with respective to the natural scaling of the system. The proof relies on the dispersive property of the linear system on the high-frequency regime and the parabolic property on the low-frequency regime. The dispersion tends to disappear when

λ

\lambda

tends to infinite, but having large

λ

\lambda

provides strong dissipation on the potential part of the velocity and thus makes the flow almost incompressible. In addition, by exploiting the intrinsic structure of the viscoelastic system, we obtain the global uniform estimates of the solutions near equilibrium.
The power of battery energy storage systems: unlocking home efficiency
Authors: Tin Thaw Tar Hla , Xydis George 
Published: January 2025

Abstract
This project explores the integration of battery energy storage systems (BESS) in residential settings to optimize energy management with a novel focus on standalone BESS configurations independent of solar photovoltaic (PV) systems. The objective is to analyze electricity price patterns, evaluate different BESS configurations, and develop strategies for efficient charging and discharging. This enables homeowners to store excess electricity during low-demand periods and discharge it during peak demand, reducing grid reliance and saving on electricity costs. The analysis reveals that a standalone BESS can reduce electricity costs by leveraging low-demand periods with electricity prices averaging 0.4 DKK/kWh, compared to peak prices exceeding 0.8 DKK/kWh. For June 2023, optimal charging (6:00–14:00, 18:00–22:00) and discharging (14:00–18:00, 23:00–6:00) periods were identified, leading to potential cost savings of up to 30 %. The findings highlight the potential of BESS to transform energy management and suggestions such as a net metering program are proposed to mitigate these challenges.