bluuebunny/crossref_metadata_2025_split huggingface dataset:
Infant feeding practices and associated factors among HIV-positive mothers of infants aged 0–6 months at public health facilities in Addis Ababa, Ethiopia
Authors: Gebremariam Zewdu Minwuyelet , Getahun Genanew , Sahile Addisu , Kejela Yared , Getachew Yeworkwuha , Sisay Fasil 
Published: February 2024

Abstract
Background
In the era of HIV infection, exclusive breast-feeding highly recommended for infants aged less than 6 months. Avoidance of exclusive breast-feeding by HIV-infected mothers recommended when replacement feeding is acceptable, feasible, affordable, sustainable and safe. The prevalence of exclusive breast-feeding has remained very low worldwide. Despite this fact, there is limited information on infant feeding practices of HIV-positive mothers and factors that affect the practice in the current study area.

Objective
This study assessed the magnitude of infant feeding practice and associated factors among HIV-positive mothers of infants aged 0–6 months at public health facilities in Addis Ababa, Ethiopia.

Methods
A multicenter facility-based cross-sectional study design was employed among a total of 397 study participants. The study participants were selected using a simple random sampling technique. The completeness of the data was checked, coded, cleaned and entered into Epi-data version 4.6 software, and exported to SPSS version 24 for analysis. Descriptive statistics and Binary logistic regression model were employed for the analysis with adjusted odds ratio (AOR) with a 95% CI and a P value ≤ 0.05 to determine the strength of association between infant feeding practice and its independent factors.

Results
The overall magnitude of appropriate infant feeding practice among HIV-positive mothers was 82.6% (95% CI 80.9–88.2). Good knowledge of mother’s toward infant feeding (AOR: 1.26, 95%, CI 1.11–3.34), better household monthly income, ≥ 6001 Ethiopian birr (AOR: 1.62, 95% CI 1.33–5.14) and favorable attitude of mother’s toward infant feeding (AOR: 1.71, 95% CI 1.01–2.92) were statistically significant associated factors with the recommended way of infant feeding practice.

Conclusions and recommendations
Hence, the current study area is the capital city of the Ethiopia, where a relatively educated population lived in, there was an opportunity for better income, and appropriate infant feeding practice among HIV-positive mothers was found slightly higher than even the overall national target (70%) that was planned by 2020. Therefore, different stakeholders should develop strategic plan to excel females’ education coverage and thereby their knowledge and attitude toward infant feeding to fully eradicate mother-to-child transmission of diseases.
Dimensional accuracy and precision and surgeon perception of additively manufactured bone models: effect of manufacturing technology and part orientation
Authors: Benca Emir , Eckhart Barbara , Stoegner Alexander , Unger Ewald , Bittner-Frank Martin , Strassl Andreas , Gahleitner Claudia , Hirtler Lena , Windhager Reinhard , Hobusch Gerhard M. , Moscato Francesco 
Published: February 2024

AbstractBackgroundAdditively manufactured (AM) anatomical bone models are primarily utilized for training and preoperative planning purposes. As such, they must meet stringent requirements, with dimensional accuracy being of utmost importance. This study aimed to evaluate the precision and accuracy of anatomical bone models manufactured using three different AM technologies: digital light processing (DLP), fused deposition modeling (FDM), and PolyJetting (PJ), built in three different part orientations. Additionally, the study sought to assess surgeons’ perceptions of how well these models mimic real bones in simulated osteosynthesis.MethodsComputer-aided design (CAD) models of six human radii were generated from computed tomography (CT) imaging data. Anatomical models were then manufactured using the three aforementioned technologies and in three different part orientations. The surfaces of all models were 3D-scanned and compared with the original CAD models. Furthermore, an anatomical model of a proximal femur including a metastatic lesion was manufactured using the three technologies, followed by (mock) osteosynthesis performed by six surgeons on each type of model. The surgeons’ perceptions of the quality and haptic properties of each model were assessed using a questionnaire.ResultsThe mean dimensional deviations from the original CAD model ranged between 0.00 and 0.13 mm with maximal inaccuracies < 1 mm for all models. In surgical simulation, PJ models achieved the highest total score on a 5-point Likert scale ranging from 1 to 5 (with 1 and 5 representing the lowest and highest level of agreement, respectively), (3.74 ± 0.99) in the surgeons’ perception assessment, followed by DLP (3.41 ± 0.99) and FDM (2.43 ± 1.02). Notably, FDM was perceived as unsuitable for surgical simulation, as the material melted during drilling and sawing.ConclusionsIn conclusion, the choice of technology and part orientation significantly influenced the accuracy and precision of additively manufactured bone models. However, all anatomical models showed satisfying accuracies and precisions, independent of the AM technology or part orientation. The anatomical and functional performance of FDM models was rated by surgeons as poor.
Role of intravoxel incoherent motion MRI in diagnosis and assessment of invasiveness of urothelial bladder carcinoma
Authors: Badawy Mohamed Ali , Zaky Samia Mounir , Korkor Mona S. , Fattah Sherif Abdel 
Published: February 2024

Abstract
Background
Urinary bladder cancer is a common malignancy. Preoperative accurate judgment of the degree of tissue invasion is crucial to determine the plan of therapy. We aimed in the current study to evaluate the role of intravoxel incoherent motion (IVIM) MRI and apparent diffusion coefficient (ADC) map in differentiating muscle invasive from non-muscle invasive carcinomas.

Results
Values of IVIM-derived true diffusion coefficient (D), pseudo-diffusion coefficient (D*) and perfusion fraction (F) and ADC were lower in muscle invasive carcinomas than non-invasive masses with p values < 0.001 and 0.001, respectively. In MIBC, ADC was (0.9 × 10−3 mm2/s), D was (0.8 × 10−3 mm2/s), D* was (6.9 × 10−3 mm2/s) and F was (16.9%). In NMIBC, ADC was (1 × 10−3 mm2/s), D was (1.1 × 10−3 mm2/s), D* was (10.2 × 10−3 mm2/s) and F was (17.7%). Mass D cut off values, sensitivity and specificity and AUC were < 0.9, 83.93, 96.30 and 0.945, respectively. Mass ADC cut off values, sensitivity and specificity and AUC were < 1.09, 87.50, 51.85 and 0.721, respectively. The degree of agreement between IVIM parameters and the pathological staging was assessed by Kappa test. The best agreement was detected for mass D (K = 0.796), while the mass ADC and wall beside mass D showed moderate and fair agreement (k = 0.418 and 0.325, respectively).

Conclusions
IVIM MRI parameters and ADC map can be utilized to detect the degree of tissue invasion caused by bladder cancer.
Surface crack treatment of concrete via nano-modified microbial carbonate precipitation
Authors: Li Tao , Yang Hanqing , Yan Xiaohui , He Maolin , Gu Haojie , Yu Liming 
Published: February 2024

AbstractAs a new concrete crack patching technology, microbial self-healing slurries offer favourable characteristics including non-pollution, ecological sustainability and good compatibility with concrete. In this paper, a nano-sio2-modified microbial bacteria liquid, combined with sodium alginate and polyvinyl alcohol, was used to prepare a nano-modified microbial self-healing slurry. This slurry was used to coat concrete under negative pressure in order to verify its restoration effect, and the micromorphology of the resulting microbial mineralization products was observed. The results revealed that patching the concrete using the nano-modified microbial slurry significantly improved its permeability, and increased its carbonization resistance by three times in comparison with the control group. Through a combination of Scanning electron microscopy (SEM) and X-ray diffraction (XRD) observation, it was determined that the microbial mineralization reaction products were mainly calcite crystals, which, integrated with the nano-sio2, sodium alginate and polyvinyl alcohol at the microscopic level, filled the internal pores of concrete, thus improving its durability.
Investigating age-related COVID-19 digital health literacy and sense of coherence among adolescents and young adults in schools across Northern Ghana
Authors: Srem-Sai Medina , Ankomah Francis , Agormedah Edmond Kwesi , Quansah Frank , Hagan John Elvis , Okan Orkan , Dadaczynski Kevin , Schack Thomas 
Published: February 2024

Abstract
Introduction
The empirical link between digital health literacy (DHL) and sense of coherence (SoC) has been extensively discussed in the literature. Yet, there seems to be limited evidence regarding the roles of age and depression status in the link between DHL and SoC of adolescents and young adults (AYAs), especially during the COVID-19 crises. This study investigated the interplay between age, DHL, SoC and psychological distress. Particularly, the study examined the following: (1) relationship between DHL and SoC, (2) moderating role of age in the relationship between DHL and SoC as well as (3) moderating role of depression in the relationship between DHL and SoC.

Methods
The study used a cross-sectional survey to select 998 AYAs in secondary schools in Northern Ghana through questionnaire administration using a stratified sampling procedure.

Results
Findings reveal that age was positively and significantly related to DHL and SoC. However, age failed to moderate the relationship between DHL and SoC. With the same level of DHL, students who exhibited depressive symptoms compared to those without, had lower levels of SoC regardless of their age.

Conclusions
Although AYAs’ DHL are likely to differ across different age brackets, this gap does not affect their rates of SoC and depression. Nonetheless, there is a need to improve DHL through regular standard training on internet search using basic audio-visual materials like laptops, smart phones, tablets, and lab computers for adolescent and young adult students. Additionally, school authorities, in collaboration with other stakeholders should develop student-centred cognitive-behavioural strategies aimed at reducing depressive symptoms in secondary school students who are at risk of depression in Northern Ghana.
The Impact of Preoperative Spinal Injection Timing on Postoperative Complications of Lumbar Decompression Surgery
Authors: Khalid Syed I. , Mirpuri Pranav , Massaad Elie , Thomson Kyle B. , Kiapour Ali , Shin John H. , Adogwa Owoicho 
Published: February 2024

BACKGROUND AND OBJECTIVES:
Epidural steroid injections (ESIs) are commonly used for lower back pain management. The effect of these injections on lumbar decompression surgery outcomes is hitherto underexplored. The study objective was to determine the impact of ESIs on postoperative rates of medical and surgical complications and to define the appropriate interval before lumbar decompression surgery.

METHODS:
This retrospective all-payer database analysis identified 587 651 adult patients undergoing one- to three-level laminectomies from January 2010 to October 2021. A 2:1 propensity score match accounting for comorbidities, levels of surgery, and demographics was performed to create two cohorts: (1) 43 674 patients who had received an ESI in the 90 days before laminectomy and (2) 87 348 patients who had not received an ESI. The primary outcome was the rates of medical and surgical complications between groups at 30 days postoperatively. Patients were divided into five cohorts based on injection time before surgery: 1 to 30 days, 31 to 45 days, 46 to 60 days, 61 to 75 days, and 76 to 90 days. Logistic regression was performed between groups to identify temporal associations of complication rates. Confidence intervals of 95% are provided when appropriate. P values < .01 were considered significant.

RESULTS:
Rates of medical complications within 30 days of surgery were significantly higher in those with ESI compared with control (4.83% vs 3.9%, P < .001). Cerebrospinal fluid (CSF) leak rates were increased in the ESI group at 0.28% vs 0.1% (P < .001), but surgical site infection rates were not significantly different between groups (1.31% vs 1.42% P = .11). ESI performed within 30 days was associated with increased odds of CSF leak (OR: 5.32, 95% CI: 3.96-7.15).

CONCLUSION:
Preoperative ESI increases the risk of CSF leak and medical complications after lumbar decompression. Because these complications were significantly associated with ESIs given 1 to 30 days before surgery, avoiding ESIs at least 30 days before surgery may be advisable.
A Retrospective Cohort Study Evaluating the Comparative Effectiveness of Unilateral Hemilaminectomy and Bilateral Laminectomy in the Resection of Spinal Meningiomas
Authors: Said Wesam , Maragno Emanuele , Leibrandt Lara , Spille Dorothee , Schipmann Stephanie , Stummer Walter , Gallus Marco , Schwake Michael 
Published: February 2024

BACKGROUND AND OBJECTIVES:
The primary treatment modality for spinal meningiomas (SM) is surgical resection. In recent years, minimal invasive spine surgery has gained considerable popularity, attributing its growth to advancements in surgical technologies and improved training of surgeons. Nonetheless, the suitability and effectiveness of minimal invasive spine surgery for intradural spinal tumor resection remain a subject of debate. In this cohort study, we aimed to compare the extent of resection of the unilateral hemilaminectomy approach, a less invasive technique, with the more traditional and invasive bilateral laminectomy.

METHODS:
We performed a retrospective cohort study including patients with SM who underwent surgery at our department between 1996 and 2020. Cohorts included patients who underwent tumor resection through bilateral laminectomy and patients who underwent a unilateral hemilaminectomy. The primary end point was extent of resection according to the Simpson classification.

RESULTS:
Of 131 with SM, 36 had a bilateral laminectomy and 95 were operated through a unilateral hemilaminectomy. In both groups, gross total resection, Simpson grades 1 and 2, was achieved in 94.44% and 94.74%, respectively (P = .999). The neurological outcome was also comparable in both cohorts (P = .356). Both length of hospital stay and estimated blood loss were significantly lower in the unilateral cohort (P < .05).

CONCLUSION:
The results of this study indicate that the unilateral hemilaminectomy yields comparable results in both oncological and neurological outcome when compared with the bilateral laminectomy. Thus, unilateral hemilaminectomy may serve as a viable and safe alternative for the surgical removal of SM.
Transpalpebral/Blepharoplasty Incision and Supraorbital Craniotomy for the Treatment of Ethmoidal Dural Arteriovenous Fistulas: A Case Series
Authors: Hagstrom Rory , Nossek Erez , Rutledge Caleb W. , Ponchione Elizabeth , Suryadevara Carter , Kremer Caroline , Alcon Andre , Sharashidze Vera , Shapiro Maksim , Raz Eytan , Nelson Peter K. , Staffenberg David A. , Riina Howard A. 
Published: February 2024

BACKGROUND AND OBJECTIVES:
Inherent complex angioarchitecture associated with ethmoidal dural arteriovenous fistulas (dAVFs) can make endovascular treatment methods challenging. Many surgical approaches are accompanied by unfavorable cosmetic results such as facial scarring. Blepharoplasty incision of the eyelid offers a minimal, well-hidden scar compared with other incision sites while offering the surgeon optimal visualization of pathogenic structures. This case series aims to report an initial assessment of the safety and efficacy of supraorbital craniotomy by blepharoplasty transpalpebral (eyelid) incision for surgical disconnection of ethmoidal dAVFs.

METHODS:
Retrospective chart review was conducted for all patients who underwent blepharoplasty incision and craniotomy for disconnection of ethmoidal dAVFs at our institution between October 2011 and February 2023. Patient charts and follow-up imaging were reviewed to report clinical and angiographic outcomes as well as periprocedural and follow-up complications.

RESULTS:
Complete obliteration and disconnection of ethmoidal dAVF was achieved in all 6 (100%) patients as confirmed by intraoperative angiogram with no resulting morbidity or mortality. Periprocedural complications included one case of transient nasal cerebrospinal fluid leak that was self-limiting and resolved before discharge without intervention.

CONCLUSION:
Surgical treatment for ethmoidal dAVFs, specifically by transpalpebral incision and supraorbital craniotomy, is a safe and effective treatment option and affords the surgeon greater access to the floor of the anterior fossa when necessary. In addition, blepharoplasty incision addressed patient concerns for facial scarring compared with other incision sites by creating a more well-hidden, minimal scar in the natural folds of the eyelid for patients with an eyelid crease.
Efficacy and safety of remimazolam in bronchoscopic sedation: A meta-analysis
Authors: Zhou Ying , Zhao Cheng , Tang Yi-Xun , Liu Ji-Tong 
Published: February 2024

BACKGROUND
Remimazolam is a new benzodiazepine used for procedural sedation and general anesthesia. Several studies have used remimazolam for bendable bronchoscopy.
AIM
To assess the safety and efficacy of remimazolam for sedation in patients undergoing bendable bronchoscopy by performing a meta-analysis of randomized controlled trials (RCTs).
METHODS
We searched the EMBASE, PubMed, Cochrane Library, and Web of Science databases for RCTs on bendable bronchoscopic procedural sedation with remimazolam vs conventional sedatives (CS).
RESULTS
Five studies with 1080 cases were included. Remimazolam had the same sedation success rate compared with CS [relative risk (RR): 1.35, 95%CI: 0.60-3.05, P = 0.474, I 2 = 99.6%]. However, remimazolam was associated with a lower incidence of hypotension (RR: 0.61; 95%CI: 0.40-0.95, P = 0.027; I 2 = 65.1%) and a lower incidence of respiratory depression (RR: 0.50, 95%CI: 0.33-0.77, P = 0.002, I 2 = 42.3%). A subgroup analysis showed a higher success rate of sedation with remimazolam than midazolam (RR: 2.45, 95%CI: 1.76-3.42, P < 0.001). Compared with propofol, the incidence of hypotension (RR: 0.45, 95%CI: 0.32-0.64, P < 0.001, I 2 = 0.0%), respiratory depression (RR: 0.48, 95%CI: 0.30-0.76, P = 0.002, I 2 = 78.4%), hypoxemia (RR: 0.36, 95%CI: 0.15-0.87, P = 0.023), and injection pain (RR: 0.04, 95%CI: 0.01-0.28, P = 0.001) were lower.
CONCLUSION
Remimazolam is safe and effective during bronchoscopy. The sedation success rate was similar to that in the CS group. However, remimazolam has a higher safety profile, with fewer inhibitory effects on respiration and circulation.
Miniaturized computational spectrometer based on two-photon absorption
Authors: Zhao Yaotian , Guo Xuhan , Xiang Jinlong , Zhao Zhenyu , Zhang Yujia , Xiao Xi , Liu Jia , Chen Daigao , Su Yikai 
Published: February 2024

On-chip spectrometers hold significant promise in the development of
laboratory-on-a-chip applications. However, the spectrometers usually
require extra on-chip or off-chip photodetectors (PDs) to sense
optical signals, resulting in increased footprints and costs. In this
paper, we address this issue by proposing a fully on-chip spectrometer
based on two-photon absorption (TPA) in a simple micro-ring resonator
(MRR) configuration. While TPA is a commonly undesired phenomenon in
conventional silicon devices due to its attached absorption losses and
nonlinearity, we exploit it as a powerful and efficient tool for
encoding spectral information, instead of using additional PDs. The
input spectrum can be reconstructed from the sensed TPA current. Our
proposed spectrometer achieves a bandwidth of 10 nm with a
resolution of 0.4 nm while occupying a small footprint of only
16×16µm2, and the bandwidth
can be further improved through several cascaded MRRs. This
advancement could enable forward fully integrated and miniaturized
spectrometers with low cost, which holds far-reaching applications in
in situ biochemical analysis, remote
sensing, and intelligent healthcare.
Burden of non-serious infections during biological use for rheumatoid arthritis
Authors: Bergmans Barbara , Jessurun Naomi , van Lint Jette , Murk Jean-Luc , van Puijenbroek Eugène , de Vries Esther 
Published: February 2024

Introduction
Biologicals have become a cornerstone in rheumatoid arthritis (RA) treatment. The increased risk of serious infections associated with their use is well-established. Non-serious infections, however, occur more frequently and are associated with a high socioeconomic burden and impact on quality of life but have not received the same attention in the literature to date. The aim of this study was to gain insight into the various non-serious infections reported in RA patients using biologicals and their experienced burden.

Materials and methods
The Dutch Biologic Monitor was a prospective observational study that included adults with rheumatoid arthritis and biological use who answered bimonthly questionnaires on the adverse drug reactions (ADRs) they experienced from their biological and reported the associated impact score (ranging from 1, no impact, to 5, very high impact). ADRs were assigned a MedDRA code by pharmacovigilance experts and labeled as definite, probable, possible or no infection by infectious disease professionals. Descriptive statistics were performed using medians and interquartile ranges.

Results
A total of 586 patients were included in the final analysis. Eighty-five patients (14.5%) reported a total of 421 ADRs labeled as probable or definite infections by the experts. Patient-assigned burden was ADR-specific. Upper respiratory tract infections were most frequently reported and had a high rate of recurrence or persistence, with a median impact score of 3.0 (IQR 2.0–3.0) which remained stable over time.

Discussion
Non-serious infections significantly outnumbered serious infections in this real-life cohort of RA patients using biologicals (77.1 non-serious infections and 1.3 serious infections per 100 patient years, respectively). Infections in the upper respiratory tract were rated as having an average burden, which remained constant over a long period of time. Awareness of the impact of recurrent and chronic non-serious infections may enable healthcare professionals to timely treat and maybe even prevent them, which would lessen the associated personal and socioeconomic burden.