bluuebunny/crossref_metadata_2025_split huggingface dataset:
A RETROSPECTIVE COHORT STUDY OF THE USE OF A PROPRIETY CALCIUM SULPHATE/HYDROXYAPATITE/ANTIBIOTIC COMPOUND (CERAMENT G) IN THE SURGICAL TREATMENT OF DIABETIC FOOT
Authors: Page Jonathan , Mackenney Paul 
Published: November 2023

Diabetic foot problems are a common cause for hospitalisation in this group and up to 25% of diabetic patients will be affected. Prevalence of diabetes is rising, currently affecting 680000000 people worldwide. The enormity of this problem mandates any strategy that shortens therapeutic period and enhances success rates. Cerament G has been used in our unit as a treatment adjunct in diabetic foot treatment. Successful treatment is viewed as eradication of infection and a functional foot.Retrospective review of 40 months practice with 115 patients. Inclusion: all diabetic feet requiring surgery Cerament G used, protocol driven Microbiology pathway. Exclusion: Primary closure not possible. Cerament G not used. Outcome assessed in three groups: Total failure (further surgery required); slow to heal (healing by secondary intention); healed without problems.Healed 99 (eradication of infection and return to function), failure to heal 16 (success rate: 86.1%). Infection was the cause of failure in only in 2.6% (13 failures due to patient noncompliance or poor vascularity). Accepted success rate in treating osteomyelitis in diabetic feet is 68% (medical treatment only), combination of surgery and medical is 86%. Eradication of infection is the only end point return to function is not addressed. This study shows Cerament G with surgery/systemic antibiotics provides a 97.4% success rate.Therapeutic drivers in this field have been determined traditionally by Physicians and Vascular Surgeons (resection rather than reconstructive surgery.) Our assertion is that eradicating infection in a functionally useless foot is a waste of health resources. Our strategy is always the delivery of an intact functional foot residuum. Cerament G as an adjunct allows this goal in a cost-effective manner.
Molecular subtypes of Adenovirus-associated acute respiratory infection outbreak in children in Northern Vietnam and risk factors of more severe cases
Authors: Nguyen Dinh-Dung , Phung Lan Tuyet , Thanh Tran Huyen Thi , Ly Ha Thi Thanh , Vo Anh Hang Mai , Dinh Nhung Phuong , Doan Phuong Mai , Nguyen Anh Thi , Dang Luc Danh , Doan Thia Thi , Pham Khuong Thi , Pham Huong Lan , Hoang Dai Xuan , Pham Thao Ngoc , Tran Bao Thai , Tran Trang Thi Thuc , Le Huong Thi Minh , Pham An Nhat , Antoniou Antony , Ho Nhan Thi 
Published: November 2023

Background
Under the pressure of Human Adenovirus (HAdV)–associated acute respiratory infection (ARI) outbreak in children in Northern Vietnam in the end of 2022, this study was initiated to identify the HAdV subtype(s) and examine the associated clinical features and risk factors of more severe cases.

Methods
This study evaluated pediatric patients with ARI which had tested positive for HAdV between October and November 2022 using a multiplex real-time PCR panel. Nasopharyngeal aspirates or nasal swab samples were used for sequencing to identify HAdV subtypes. Clinical data were collected retrospectively.

Results
Among 97 successfully sequenced samples, the predominant subtypes were HAdV-B3 (83%), HAdV-B7 (16%) and HAdV-C2 (1%). Lower respiratory manifestations were found in 25% of the patients of which 5% were diagnosed with severe pneumonia. There was no significant association between HAdV subtype and clinical features except higher white blood cell and neutrophil counts in those detected with HAdV-B3 (p<0.001). Co-detection of HAdV with ≥1 other respiratory viruses was found in 13/24(54%) of those with lower respiratory manifestations and 4/5(80%) of those with severe pneumonia (odds ratio (95% confidence interval) vs. those without = 10.74 (2.83, 48.17) and 19.44 (2.12, 492.73) respectively after adjusting for age, sex, birth delivery method, day of disease).

Conclusion
HAdV-B3 and HAdV-B7 were predominant in the outbreak. Co-detection of HAdV together with other respiratory viruses was a strong risk factor for lower respiratory tract illnesses and severe pneumonia. The findings advocate the advantages of multi-factor microbial panels for the diagnosis and prognosis of ARI in children.
Design and implementation of a frequency reconfigurable antenna using PIN switch for sub-6 GHz applications
Authors: Abdulhussein Akram Jabbar , Farhan Malik Jasim , Ali Ghusoon M. 
Published: November 2023

Abstract
The future of 5G New Radio development has many significant concerns. We present and investigate a frequency-reconfigurable antenna based on a PIN diode to overcome the working frequency band issue. The dimensions are 30 mm × 20 mm × 1.6 mm, built on material substrate (FR-4) with a relative permittivity of

ε

r

{\varepsilon }_{{\rm{r}}}

= 4.4. Two switches allow frequency reconfiguration in the antenna, giving us three operation modes. The design in mode 1 (SW1 = Off and SW2 = Off) covers a 4.6 GHz band. The proposed design in mode 2 resonated at 2.7 and 4.8 GHz (SW1 = On, SW2 = Off or SW1 = Off, SW2 = On), while the design in mode 3 operated at 3.6 GHz (SW1 = On, SW2 = On). Before fabrication, the proposed design is simulated by the Computer Simulation Technology microwave studio software. The presentation and discussion of the radiated pattern and S parameter demonstrate the practicability of the proposed design. The design module’s dimensions and performance are both precisely appropriate. The results indicate a good agreement between both simulation and experimental findings.
Effect of prototypicality and dual route processing modal on instructed second language acquisition of Chinese resultative verb compounds
Authors: Zhang Yafeng , Pandian Ambigapathy , Soo Ruey Shing 
Published: November 2023

Abstract
The present study investigates the processing of Chinese Resultative Verb Compounds (RVCs) in second language (L2) learners. It focuses on the role of prototypicality of component morphemes and whole-word token frequency in L2 acquisition of Chinese RVCs in a formal instructional setting. Chinese RVC is an important linguistic item in Chinese as second or foreign language (CSL/CFL). Cognitive psychology and other areas of research have found that both components of compound and whole word have effect on compound identification. Based on these findings, Pollatsek and his fellows (2000) proposed dual route processing modal (DRPM) which claimed that both the frequency of components and whole-word frequency have effect on compound identification. However, as regards the frequency effect, more empirical evidences showed that prototypicality is a better indicator than frequency in predicting the acquisition of compound. This study aims to explore the effect of formal instruction, prototypicality of components and whole word frequency on RVC identification. By adopting Zhang. (2023. [Forthcoming] Morphological prototypicality of Chinese verb compound and components. Chinese Journal of Applied Linguistics)’s hierarchy of prototypical V1s and RCs, forty two students in two intact classes from Malaysia secondary school participate in a prestest-intervention-posttest research. According to finding in the quasi-experiment study, prototype-based DRPM is proposed with the pedagogical implications that might be conducive to the area of CSL/CFL learning.
Interpersonal strategies in international business emails: The intercultural pragmatics perspective
Authors: Liu Ping , Liu Huiying 
Published: November 2023

Abstract
Business email has a significant impact on commercial activities and organizational image. Intercultural pragmatics is the new development of pragmatics, moving its focus from mono-cultural communication to multi-cultural communication, aiming to describe how communicators seek, activate, and create common ground to complete tasks in intercultural communication contexts. Drawing on 1,477 separate English emails exchanged between a Chinese auto parts export company and its business partners in different parts of the world, we find, from the intercultural pragmatics perspective, that different types of interpersonal strategies, i.e., alliance building, other-caring, and self-enhancing/defending, are employed to construct virtual intimacy and to create and highlight interpersonal relationship dimensions in international business communication. These strategies are intended to facilitate the accomplishment of communication tasks by creating emergent common ground, reflecting the dynamics and interculturality of business communication. This research deepens our understanding of the mechanism of relationship management in international business communication.
Teacher behaviour and student engagement with L2 writing feedback: a case study
Authors: Luo Na 
Published: November 2023

Abstract
Feedback is essential for student learning and engagement is key for its efficacy. Yet research on student engagement with feedback predominantly attributes it to learner factors, overlooking teacher influence. This case study explored how one writing teacher’s behaviours shaped a motivated undergraduate’s engagement with various types of feedback in a writing course over one semester. Data sources included interviews, class observations, and text analysis. Findings revealed the pivotal role of teacher feedback behaviours in shaping student engagement, often through complex interactions with learner factors and teacher non-feedback behaviours. While some feedback behaviours enhanced student engagement, most had negligible or detrimental effects, highlighting the contextual nature of “best practices”. Certain teacher behaviours also exerted lasting impacts on student engagement. Additionally, some teacher non-feedback behaviours, both teaching and non-teaching, also contributed to shaping student engagement. These findings have implications for both research and teacher education.
Legitimate Tax Structures: Lessons from the Past
Authors: Colombatto Enrico 
Published: November 2023

Abstract
Today’s views and analyses about taxation are dominated by the social-welfare approach based on various categories of utilitarianism, most notably those developed by the optimal-tax literature. By contrast, this paper focuses on the ethical foundations of taxation and analyses a tradition that harks back to the 17th century. In particular, we emphasise the notion of legitimate taxation in the history of economic thought from the libertarian, the classical-liberal and socialist perspectives. By means of this very notion, we define the essence of a desirable tax structure and draw conclusions in regard to today’s tax policies.
Crystal structure of (8R,8′S,13S,13′R)-8,8′-bis(hydroxymethyl)-9,9′,10,10′-tetramethoxy-5,5′,6,6′,8,8′,13,13′-octahydro-[13,13′-bi[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline]-7,7′-diium chloride-methanol (1/2), C46H58N2O14Cl2
Authors: Han Wei , Li Mei , Geng Xiang , Zhang Guoshun 
Published: November 2023

Abstract
C46H58N2O14Cl2, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 7.5623(2) Å, b = 10.87056(17) Å, c = 13.90486(15) Å, α = 105.7122(12)°, β = 98.907(2)°, γ = 91.067(2)°, V = 1084.88(4) Å3, Z = 1, R

gt
(F) = 0.0341, wR

ref
(F
2) = 0.0935, T = 100(2) K.
A review on application of green nanoparticles from neem and eucalyptus
Authors: Narayanankutty Akhila , Sharma Anuradha , Singh Amrita 
Published: November 2023

Abstract
Nanotechnology is concerned with the creation and use of nanoscale materials. The synthetic methods for nanoparticles are associated with environmental hazards. This review begins with the need for synthesizing nanoparticles biogenically. Hence, it describes the green synthesis of different metal nanoparticles using the plant extracts of neem (Azadirachta indica), and eucalyptus (Eucalyptus globulus) as reductant and stabilizers. Importantly, this review summarizes the medical applications of green nanoparticles, made using plants with medicinal values. The environmental uses of the same nanoparticles are also explored. There is immense literature where nanoparticle-based applications in medicine and environment concentrates more on chemical or physical methods, we hope this review would help reader to focus more on environment friendly synthesis of nanoparticles and their important roles.
EZH2 inhibition stimulates repetitive element expression and viral mimicry in resting splenic B cells
Authors: Kim Seung J , Kiser Patti K , Asfaha Samuel , DeKoter Rodney P , Dick Frederick A 
Published: November 2023

AbstractMammalian cells repress expression of repetitive genomic sequences by forming heterochromatin. However, the consequences of ectopic repeat expression remain unclear. Here we demonstrate that inhibitors of EZH2, the catalytic subunit of the Polycomb repressive complex 2 (PRC2), stimulate repeat misexpression and cell death in resting splenic B cells. B cells are uniquely sensitive to these agents because they exhibit high levels of histone H3 lysine 27 trimethylation (H3K27me3) and correspondingly low DNA methylation at repeat elements. We generated a pattern recognition receptor loss‐of‐function mouse model, called RIC, with mutations in Rigi (encoding for RIG‐I), Ifih1 (MDA5), and Cgas. In both wildtype and RIC mutant B cells, EZH2 inhibition caused loss of H3K27me3 at repetitive elements and upregulated their expression. However, NF‐κB‐dependent expression of inflammatory chemokines and subsequent cell death was suppressed by the RIC mutations. We further show that inhibition of EZH2 in cancer cells requires the same pattern recognition receptors to activate an interferon response. Together, the results reveal chemokine expression induced by EZH2 inhibitors in B cells as a novel inflammatory response to genomic repeat expression. Given the overlap of genes induced by EZH2 inhibitors and Epstein–Barr virus infection, this response can be described as a form of viral mimicry.
Review of best treatment option in heart failure 2023
Authors: Santiago Gerardo Garcia , Gomez Andrea Marin , Gonzalez Guillermo Avalos , Ramos Oscar Jesus Leal , Castro Alejandra Arias , Pere Mariano Belisario López 
Published: November 2023

Congestive heart failure is a clinical condition in which the heart is unable to pump enough blood to meet the metabolic needs of the body because of pathological changes in the myocardium. The three main causes of CHF are coronary artery disease, diabetes mellitus, and hypertension. US hospitalizations for heart failure decreased up until 2012; however, from 2013 to 2017, an increase in HF hospitalizations was observed. In 2017, there were 1.2 million HF hospitalizations in the United States among 924 000 patients with HF. This represents a 26% increase in HF hospitalizations and number of patients hospitalized with HF. For this reason, as a team, we have decided to conduct a review of the best treatment options for heart failure based on multiple articles.
Formative Assessment in a Geology Classroom: Promoting Learning by Giving Top Marks
Authors: Helman Daniel S. 
Published: November 2023

Based on the observation that teacher expectation often drives classroom success, a project was undertaken whereby all students were given top marks in two sections of a geology classroom at the undergraduate level. To further this project, a student motivation strategy was attempted to take the place of their not having to fear for top marks. The results were sixfold: (1) the results of student work were well above average; (2) student work reflected teacher expectations; (3) student enthusiasm was well above average; (4) the instructor needed to use enthusiasm and humor to maintain discipline; (5) the instructor needed to parse the assignments so that the work would be done; (6) the administration was unhappy with the resulting data analytics. Based on this case study, one can confirm that student outcomes are highly dependent on teacher expectations and strategies; and that formative (not evaluative) assessments can be used effectively to raise the level of student learning.
A quasi-geostrophic analysis of summertime southern African linear-regime westerly waves
Authors: Ndarana Thando , Rammopo Tsholanang , Bopape Mary-Jane , Hart Neil , Reason Chris , Chikoore Hector 
Published: November 2023

Abstract
Linear-regime westerly waves that propagate across the South African domain are often linked to well-known rainfall producing systems such as tropical temperate troughs and synoptic scale tropical low-pressure systems, and ridging South Atlantic Ocean anticyclones at the surface. It is accepted that the baroclinic waves that propagate across the domain provide the lifting mechanism that causes the required vertical motion for rainfall to occur. This study shows that there exists a jet streak embedded in these waves that is located downstream of the trough axis, to the east of which vertically upward motion is expected to occur. The entrance of the jet streak passes just south of the country, as the waves propagate past the domain.

The study further shows that for this class of waves, the vertical motion that causes rainfall to occur is induced by the thermally direct transverse ageostrophic circulation that is located at this jet entrance. This is instead of the conventional upper air divergence that is located at the inflection point east of the trough axis. Using a method of decomposing the Q-vector into its transverse (Qs) and shear (Qs) components, the divergence fields of which are used to decompose the vertical motion into the corresponding components, i.e ωn and ωs, respectively; it was shown that the vertical motion over South Africa is explained more by the former than the latter. Therefore, the uplift over the country and that located at the infection point east of the trough are dynamically distinct processes. Taking the limitations of the quasi-geostrophic framework into consideration, the study concludes that during the passage of linear-regime waves vertical motion that might lead to rainfall is caused by the circulation at the jet entrance and not the divergence in the baroclinic wave.
The role of kidney function in the association between pro- inflammatory diet and cognitive impairment: NHANES from 2011 - 2014
Authors: Duan Weiwei , Yuan Bo , Xia Zhiwei 
Published: November 2023

Abstract
Aims: It has been well known that the higher inflammation levels are associated with the higher risk of cognitive impairment. Therefore, a high pro-inflammation diet may increase the risk of cognitive impairment by inducing the body’s inflammation process. At the same time, chronic kidney disease (CKD) is also a common risk factor of the cognitive impairment, in this article, we try to investigate if the kidney function or CKD plays a mediating role between pro-inflammation diet and cognitive impairment.
Methods and results: Data for this study were acquired from NHANES database, and 3124 participants were enrolled based on the dietary inflammation index (DII) and some essential cognitive tests such as the AF, CERAD-WL, CERAD-DR, and DSST. Subgroup analysis, trend analysis, and logistic regression were used to evaluate the correlation between DII and cognitive impairment. The study found that mean DII score was higher in those with cognitive impairment than those with normal cognition, the logistic regression revealed that high DII was associated with the cognitive impairment, and the proportion of individuals with cognitive impairment increased gradually as the DII level increased (p. trend < 0.001). Further mediation analysis was performed to investigate whether CKD mediates the association between cognitive impairment and pro-inflammatory diets, and revealed that the influence of DII on cognitive impairment was partially due to the indirection effect through kidney function, the indirection effect was -0.015(29.9% of the total effect value)
Conclusion: Pro-inflammatory diet (high DII) is associated with cognitive impairment, and this association is partially mediated by CKD.
Revisiting the predictability of follicular fluid leptin and related adiposity measures for live birth in women scheduled for ICSI cycles, a prospective cohort study.
Authors: A; Abdelmagied , Makhlouf Alaa A. , Abdel-Aleem Ahmed A. , Mohamed Safwat A. , Nasr Ahmed , Elfadl Azza Abo , Ali Mohammed K. 
Published: November 2023

Abstract
Background
Our research question is; could follicular fluid (FF) leptin solely or contemporaneously with other clinical, biochemical and sonographic adiposity measures predict the probability of having a live birth during ICSI cycles? .This is a prospective cohort study that enrolled infertile women without polycystic ovary syndrome scheduled for ICSI. At baseline, women had assessment of obesity using different metrics: clinical, serum biochemical, and sonographic. Clinical measures encompassed waist circumference and body mass index. Biochemical evaluation comprised assessment of homeostasis-model for insulin resistance, visceral adiposity index and lipid accumulation product. Preperitoneal and subcutaneous abdominal fat were measured using ultrasound and body fat index was calculated. On day of oocyte retrieval, pooled FF was sampled to assess FF leptin. Our primary outcome was live birth after one fresh embryo transfer cycle.
Results
Out of Ninty-one women analyzed in this study, 28 have a live birth (30.8%). No difference in FF leptin concentration was found between women with and without live birth (Mean ± SD; 20336 ± 8006 vs 18493 ± 6655 pg/ml; P = 0.2). None of the assessed adiposity markers was a predictor for live birth. Substantially, follicular fluid leptin was positively correlated with insulin resistance in women with and without live birth (r = 0.21, P = 0.04). In logistic regression analysis, the outcome of the prior cycle, ability to have cryopreserved embryos, and the oocyte maturation index were the predictors for live birth in our study.
Conclusions
The present work could not find evidence that follicular fluid leptin, preperitoneal fat and other evaluated adiposity measures could impact live birth after ICSI cycles.
Mutations of Dipylidium caninum Cestode diagnosis of Dogs in Baghdad city, Iraq
Authors: Salih Dunya Abd Al-Malik Mohammed , Altaii Noor A. , Baghdad-Iraq Nuha K. Khalil 
Published: November 2023

Abstract
Objective. This study’s goal included a traditional and molecular detection of Dipylidium caninum cestode in dogs in Baghdad city.
Materials and Methods. conducted 22 mature cestode obtained from 15 intestines of dead 100 dogs for morphological description by necked eye to see the D.caninum segments, body’s length and proglottids; and for conventional-PCR technique by amplified two primer pairs; DC28SrRNA and mtDNA gene, sequencing and analysis of molecular data.
Results. were for the first time in dogs in Iraq and Local D.caninum Iraqi isolates with accession no. MZ677330, OL413446, OL460637 shared 99.93% identity with South Africa and 93.75% identity with Viet Nam sequence (accession no. MH045471.1 and ON248386.1 respectively). Local D.caninum Iraqi isolates with accession no. OL460638 and OL466918 shared related 97.63% identity to those from New Zealand (accession no. MG57541.1); two isolates from USA shared related 93.36% identity with accession no. AF023120.1 and MH182478.1; and Iran shared related 93.57% identity with accession no. MG774549.1) with mutations recording minor variance in genetic (0.01) across all comparison isolates. Also mtDNA gene partial sequences with accession no. OR250020.1 shared 98-99% with USA (accession no. OK523385.1 and MG587892.1) and China (accession no. OP620562.1) with substitution through sequences: deletion of OR250020.1 (9,-/C).