bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigating the impact of anthropogenic noise on the decision-making of dwarf mongoose offspring
Authors: Vane Lauren S , Morris-Drake Amy , Arbon Josh J , Thomson Robyn , Kern Julie M , Radford Andrew N 
Published: January 2024

Abstract
Anthropogenic (man-made) noise constitutes a novel and widespread pollutant, with its increasing prevalence in terrestrial and aquatic ecosystems resulting in alterations of natural soundscapes. There is proliferating evidence that noise leads to maladaptive behaviour in wildlife, yet few studies have addressed the effect on mammalian parent–offspring interactions. We investigated the impact of road noise on dwarf mongoose (Helogale parvula) offspring nearest-neighbour decision-making whilst foraging, using a field-based playback experiment. We predicted that offspring would forage closer to groupmates, especially adult and dominant individuals, when experiencing road noise compared to ambient sound to reduce communication masking and alleviate stress. We also predicted that noise would have a reduced effect with increasing offspring age due to reduced reliance on adult groupmates for provisioning and predator-defence. However, we found that mean nearest-neighbour distance and nearest-neighbour intrinsic characteristics (age, sex and dominance status) did not differ significantly between sound treatments, and these responses did not vary significantly with focal individual age. Noise may not impact nearest-neighbour decision-making due to habituation from chronic natural exposure; alternatively, noise could induce stress and distraction, resulting in maladaptive decision-making. Future work should aim to detangle the underlying mechanisms mediating parent–offspring interactions in conditions of anthropogenic noise.
Screening of compounds-based on intermediate adsorption equilibrium for electrocatalytic nitrate reduction to ammonia
Authors: Wang An-Liang , Ma Chaoqun , Zhang Huaifang , Xia Jing , Zhu Xiaojuan , Qu Kaiyu , Feng Fukai , Han Sumei , He Caihong , Ma Xiao , Lin Gang , Cao Wenbin , Meng Xiangmin , Zhu Lijie , Lu Qipeng 
Published: January 2024

Abstract
Electrocatalytic nitrate (NO3-) reduction reaction (NO3RR) holds great potential for the conversion of NO3- contaminants into valuable ammonia in a sustainable method. Unfortunately, the non-equilibrium adsorption of intermediates and sluggish multi-electron transfer have detrimental impacts on the electrocatalytic performance of the NO3RR, posing obstacles to its practical application. Herein, we initially screen the adsorption energies of three key intermediates, i.e., *NO3, *NO and *H2O, along with the d-band centers on 21 types of transition metals (IIIV and IB)-Sb/Bi based intermetallic compounds (IMCs) as electrocatalysts. The results reveal that hexagonal CoSb IMCs possess the optimal adsorption equilibrium for key intermediates, and exhibit outstanding electrocatalytic NO3RR performance with Faradaic efficiency of 96.3%, NH3 selectivity of 89.1% and excellent stability, surpassing the majority of recently reported NO3RR electrocatalysts. Moreover, the integration of CoSb IMCs/C into a novel Zn-NO3- battery results in a high power density of 11.88 mW cm-2.
Comparing the accuracy of wearable devices readings with cuff sphygmomanometers for blood pressure measurement: Systematic Review and Meta-analysis
Authors: Cai Jingjing , Li Zhengxin , Wen Qing , Sun Xuejing , Wu Junru , Lu Yao , He Tian , Zhang Wen , Yuan Hong 
Published: January 2024

Abstract
Wearable devices for BP measurement as an emerging technology for closer monitoring BP and achieving better BP control monitoring. However, the accuracy of wearable devices needs to be systematically validated and analyzed. This study aims to compare wearable device readings for BP measurement with those from cuff sphygmomanometers in prospective clinical studies, therefore, to determine whether wearable devices provide reliable and portable BP monitoring. The Web of Science, MEDLINE, Embase, Cochrane Library, and PubMed databases were searched from January 1, 1952 to October 8, 2021. Data were compiled from 21 articles comprising 897 participants. There was no significant difference between systolic and diastolic readings for wearable devices and cuff sphygmomanometers, with a combined mean difference of 0.58 mmHg (95% CI, -0.35 to 1.51; n = 21; I²=0%, P = 0.22) for SBP and − 0.33 mmHg (95% CI, -1.50 to 0.85; n = 19; I²=56%, P = 0.58) for DBP. The subgroup analysis showed that BP readings of wearable devices lower than cuff sphygmomanometers at the wrist site (-1.85mm Hg, 95% CI, -2.75 to -0.95; n = 11; I² = 10%, P༜0.05). Wearable device measurement for BP is comparable to the readings of cuff sphygmomanometers. Although the accuracy still should be improved, wearable device measurement may be a reliable and convenient approach for daily BP monitoring to improve BP control.
Chest CT Findings for IgG4-related Disease
Authors: Liu Ye , Nie Yongkang 
Published: January 2024

Abstract

Objective To investigate the multi-slice spiral CT (MSCT) findings of chest involvement in IgG4-related diseases, and to improve doctors' understanding of this disease.
Methods A retrospective analysis was carried out on the clinical and imaging data of 67 patients with clinically confirmed or suspected IgG4-related diseases.
Results: A total of 60 patients (89.60%) had abnormal chest CT. Among them, 47 patients (70.10%) had enlarged mediastinal lymph nodes. Thickening of the tracheal and tracheobronchial perivascular wall was found in 35 cases (52.20%). Nodules were found in 29 cases (43.30%). There was patch or ground-glass density in 15 cases (22.40%), bilateral enlarged axillary lymph nodes in 9 cases (13.40%), bilateral enlarged hilar lymph nodes in 3 cases (4.50%) and interstitial changes in 8 cases (11.90%). Pleural effusion occurred in 5 cases (7.46%, 2 cases of bilateral and 3 cases of unilateral), and pericardial effusion in 3 cases (4.50%). Seven cases (10.45%) showed no obvious abnormality. The abnormally elevated IgG4 (>135mg/dL) was positively correlated with the thickening of the tracheal and tracheobronchial wall (r = 0.328, p = 0.007) and the enlargement of mediastinal lymph nodes (r = -0.252, p = 0.039); Logistic regression model 1 showed that the incidence of lung as the first symptom was increased in patients with bilateral enlarged hilar lymph node on chest images (OR = 16. 000, 95% CI: 1.280-200.010).
Conclusion: The abnormal manifestations of chest lesions, especially lung involvement, on IgG4-RD were varied. Peribronchovascular involvement and lymph node enlargement are the most common manifestations. Chest CT examination is of great significance in the diagnosis and follow-up of IgG4-RLD.
Exergoeconomic based comparative analysis between NH3-NaSCN single effect absorption cycle, combined compression-absorption refrigeration and combined ejector-absorption refrigeration cycles powered by solar panel
Authors: Rabiei Reyhaneh , Borji Mehdi , Kazemi Admin 
Published: January 2024

Abstract

Solar cooling is environmentally friendly and relies on solar energy to meet cooling needs. In recent years, absorption chillers have gained interest as a sustainable alternative to vapor compression chillers using eco-friendly refrigerants. However, a major problem with simple absorption systems is their low coefficient of performance. As a result, researchers are exploring ways to improve their thermoeconomic efficiency. In this research, three different configurations of absorption cycles are compared and analyzed from exergetic and exergoeconomic points of view. These configurations include the simple absorption cycle, the combined ejector-absorption cycle, and the combined compression-absorption cycle, as well as a flat plate solar collector and a storage tank. Ammonia sodium thiocyanate is used as the working solution. In both combined cycles, the absorber operates at intermediate pressure, allowing three pressure levels to be considered. The simulations are carried out using EES software. The results show that the solar collector should be considered more than other components in terms of exergy and exergoeconomic. It is observed that for the same pressure ratio of ejector and compressor, the exergy efficiency of the ejector cycle is slightly higher than that of the compression cycle. Also, in most cases, the results show improved performance in the combined solar compression cycle by increasing the compressor pressure ratio compared to the other cycles. It has also been shown that increasing the pressure ratio of the ejector and compressor improves the exergoeconomic performance of the combined cycles compared to the simple absorption cycle.
Integrated geophysical methods for studying the karst system of Ravansar
Authors: Baghzendani Hamidreza , Aghajani Hamid , Karami Gholam Hossein 
Published: January 2024

Abstract

Karsts are important sources of water, and it is crucial to determine their water volume and quality. The Ravansar karst spring in Kermanshah province is a significant water resource with a substantial water volume in the area. The source of this spring is the carbonate rock unit from the Cretaceous period and is affected by tectonic changes and faulting caused by movements related to Zagros folding. In this study, geophysical methods of microgravity, electrical resistivity, and induced polarization have been utilized to identify the feeding sources of Ravansar spring and the extent of karst development in the limestone units. The microgravity method was employed to generate the residual gravity anomaly map of the area, as the decrease in density and increase in porosity resulted from karstification. The minimum residual gravity values are associated with caving and karstification. As a result, the gravity anomalies of the range were examined, and three-dimensional modeling was conducted on the gravity data. In this manner, we were able to identify not only cave-shaped voids and spacious cave chambers, but also sub-structures and micro-karstification in carbonate rocks. The most significant finding from the field survey is the detection of low gravimetric values, indicating relatively large holes and chambers that are previously unknown and inaccessible from ground level. These findings are consistent with known collapse and sediment infill features, as seen in surface sinkholes, cavities, and karstification systems.In addition to the gravimetric method, electrical resistivity and induced polarization surveys (IP & Res) were conducted to explore the subsurface geology in the chosen area. The purpose of this research was to visualize karst cavities and identify areas at risk of land subsidence due to cavity collapse. The field dataset comprised two electrical profiles acquired using a dipole-dipole electrode configuration. The resistivity data was inverted using a two-dimensional algorithm based on the least square’s technique with a smoothing constraint. Geophysical surveys and field surveys show that the holes and karsts in the area are related to tectonic phenomena and faulting and are conduits for transporting water to the Ravansar spring.
Defective thyroid hormone transport to the brain leads to astroglial alterations
Authors: Guillén-Yunta Marina , García-Aldea Ángel , Valcárcel-Hernández Víctor , Sanz-Bógalo Ainara , Muñoz-Moreno Emma , Matheus Maria Gisele , Grijota-Martínez Carmen , Bárez-López Soledad , Montero-Pedrazuela Ana , Guadaño-Ferraz Ana 
Published: January 2024

Abstract
Background: Allan-Herndon-Dudley syndrome (AHDS) is a rare X-linked disorder that causes severe neurological damage, for which there is no effective treatment. AHDS is due to inactivating mutations in the thyroid hormone transporter MCT8 that impair the entry of thyroid hormones into the brain, resulting in cerebral hypothyroidism. However, the pathophysiology of AHDS is still not fully understood and this is essential to develop therapeutic strategies. Based on evidence suggesting that thyroid hormone deficit leads to alterations in astroglial cells, including gliosis, in this work we have evaluated astroglial impairments in MCT8 deficiency.
Methods: We conducted magnetic resonance imaging on both control subjects and MCT8-deficient patients to examine changes in brain cytoarchitecture. Moreover, to gain further understanding on these alterations in brain cytoarchitecture and the astroglial population, we have performed histological and immunohistochemical approaches in autopsy brain samples from an 11-year-old and a 30th gestational week MCT8-deficient subjects in comparison to brain samples from control subjects at similar ages. Findings from MCT8-deficient subjects were validated and further explored in a mouse model of the AHDS.
Results: Magnetic resonance imaging showed changes indicative of alterations in brain cytoarchitecture in MCT8-deficient patients. Further studies confirmed changes in the astroglial population in MCT8 deficiency that arise early in brain development and persist at adult stages, revealing an abnormal distribution, density, and morphology of cortical astrocytes, compatible with an astrogliosis-like phenotype at adult stages.
Conclusions: We have identified astrocytes as potential novel therapeutic targets in AHDS. In addition, we propose ADC imaging as a tool to monitor the progression of neurological impairments and potential effects of treatments in MCT8 deficiency.
In-situ valve opening response of eastern oysters to estuarine conditions
Authors: Lavaud Romain , Archer Stephanie , Peyre Megan La , Campanino Finella , Casas Sandra , Peyre Jerome La 
Published: January 2024

Abstract

High-frequency recording of valve opening behavior (VOB) in bivalves is often used to detect changes in environmental conditions. Generally, though, focus is put on a single variable such as temperature or the presence of toxicants in the water. Description of routine VOB under non-stressful conditions is also important to interpret responses to environmental changes. Here we present the first detailed quantitative investigation of the in-situ VOB of eastern oysters (Crassostrea virginica) to environmental variables typically not considered stressful. The VOB of eight individuals was monitored for seven weeks in a Louisiana estuary. We examined the relationship between VOB metrics (inter-individual variability, the probability of an oyster being closed, and the rate of valve closure), and temperature, salinity, chlorophyll-a (chl-a) concentration, the rate of change in those environmental variables, and the rate of change in water depth. Relationships were analyzed through statistical models including rates of change over 0, 0.25, 1-, 6-, 12-, and 24-hours. All responses were best explained by the 12-hour time step model. The interaction between salinity and the rate of change of salinity had the most impact on inter-individual variability. Oysters closed faster at higher salinities and were more likely to be closed at lower chl-a concentrations. Significant interactions were found between many environmental variables, indicating the high level of complexity of oyster behavior in the natural environment. This study contributes to the better understanding of the impact of environmental conditions on oyster behavior and can help inform predictive tools for restoration initiatives and fisheries practices.
Using modified descriptive analysis and instrumental measurements to assess the impact of grape smoke exposure on the wine matrix of different red wine varietals in California
Authors: Lim Lik Xian , Medina-Plaza Cristina , Arías-Perez Ignacio , Wen Yan , Neupane Bishnu , Lerno Larry , Guinard Jean-Xavier , Oberholster Anita 
Published: January 2024

Abstract

This study is an investigation of the impact of volatile phenols (VPs) released from burning wood during wildfires on grape composition and the resulting wines. Baseline levels of VPs in grapes and sensory differences between smoke-impacted wines and non-smoke-impacted wines were determined, and related to different levels of smoke taint marker compounds in different wine matrices, using modified descriptive analysis (DA), multivariate statistics, gas chromatography mass spectrometry (GC-MS) and liquid chromatography-triple quadrupole tandem mass spectrometry (LC-QqQ-MS) of the free and total VPs, and individual bound glycosides, respectively. Across two DA panels, Cabernet Sauvignon, Cabernet Franc, Petite Verdot, Merlot, Syrah, Malbec, and Zinfandel spread across California were evaluated. The results show sensory differences between highly smoke-impacted and non-impacted wines with wines made from highly smoke-impacted grapes characterized as smoky, barbeque, medicinal, and having a retro-nasal ashtray character. Low smoke-impact wines based on free and total VP concentrations were not significantly different from the non-impacted wines when rated through descriptive analysis. The amount of smoke exposure was the largest contributor to smoke impact, but the different wine matrices from different locations and varietals also played an important role in determining the level of perceived smoke taint. The results of this study will contribute to our understanding of smoke taint and how it impacts wine quality by relating smoke marker indicator compounds to wine sensory attributes.
Interruptible Demyelination in Avian Riboflavin Deficient Neuropathy
Authors: Cai Zhao 
Published: January 2024

Abstract

Background and aims: The evolution of demyelination in individual internodes remains unclear although it has been noticed the paranodal demyelination precedes internodal demyelination in neuropathies with diverse aetiologies. For therapeutic purpose, it is fundamental to know whether the demyelinating procedure in affected internodes can be interrupted. This study aimed to delineate the development of demyelination in individual internodes in avian riboflavin deficient neuropathy.
Methods: Newborn broiler meat chickens were maintained either on a routine diet containing 5.0 mg/kg riboflavin, a riboflavin deficient diet containing 1.8 mg/kg riboflavin, or initially a riboflavin deficient diet for 11 days and then routine diet plus riboflavin repletion from day 12. Evolution of demyelination in individual internodes was analyzed by teased nerve fibre studies from day 11 to 21.
Results: In riboflavin deficient chickens, demyelination was the predominant feature: it was mainly confined to the paranodal region at day 11; extended into internodal region, but less than half of the internodal length in most affected internodes at day 16; involved more than half or whole internode at day 21. In the internode undergoing demyelination, myelin degeneration of varying degrees was noticed in the cytoplasm of the Schwann cell wrapping the internode. Two days after riboflavin repletion, co-existence of remyelination and active demyelination within individual internodes was noticed. Remyelination together with preserved short original internodes was the characteristic feature 4 and 9 days after riboflavin repletion.
Conclusion: Riboflavin repletion interrupts the progression from paranodal to internodal demyelination in riboflavin deficient chickens and promotes remyelination before complete internodal demyelination.
Genotype-specific expression of selected candidate genes conferring resistance to leaf rust of rye (Secale cereale L.)
Authors: Azad Rumana , Krępski Tomasz , Olechowski Mateusz , Biernacik Bartosz , Święcicka Magdalena , Matuszkiewicz Mateusz , Dmochowska-Boguta Marta , Rakoczy-Trojanowska Monika 
Published: January 2024

Abstract
Leaf rust (LR) caused by Puccinia recondita f. sp. secalis (Prs) is a highly destructive disease in rye. However, the genetic mechanisms underlying the rye immune response to this disease remain relatively uncharacterised. In this study, we analysed the expression of four genes in 12 rye inbred lines inoculated with a Prs at 20 and 36 h post-treatment (hpt): DXS (1-deoxy-D-xylulose 5-phosphate synthase), Glu (beta-1,3-glucanase), GT (UDP-glycosyltransferase) and PR-1 (pathogenesis-related protein 1). The RT-qPCR analysis revealed the up-regulated expression of the four genes in response to Prs in all inbred lines and at both time-points. The gene expression data were supported by the microscopic and macroscopic examination, which revealed that eight lines were susceptible to LR, and four lines were highly resistant to LR. A relationship between the infection profiles and the expression of the analysed genes was observed: in the resistant lines, the expression level fold-changes were usually higher at 20 hpt than at 36 hpt, while the opposite trend was observed in the susceptible lines. The study results indicate that DXS, Glu, GT and PR-1 may encode proteins crucial for the rye defence response to the LR pathogen.
MiR-200c inhibits the expression of zinc finger E-box-binding homeobox 1 (ZEB1) to suppress bladder cancer cell migration and invasion
Authors: Xing Fei , Hu Chunhai , Cao Tingshuai , He Li , Guo Feng 
Published: January 2024

Abstract

MiR-200c functions to modulate cell growth and differentiation and alters the miR-200c expression related to cancer development and metastasis. This study evaluated the role of miR-200c in bladder cancer cells and the underlying molecular events.
Methods:Quantitative RT-PCR was used to determine miR-200c expression in bladder cancer cell lines. Gene transfection was performed to stably restore miR-200c expression or silence miR-200c expression, and the cells were then subjected to cell viability, transwell migration and invasion, and luciferase assays.
Results:The miR-200c level was significantly downregulated in bladder cancer cells, whereas the restoration of miR-200c expression suppressed tumor cell migration and invasion capacity. Antagonizing miR-200c drastically acceleratedtumor cellinvasion, migration capacity. At the gene level, miR-200c targeted zinc finger E-box binding homeobox 1( ZEB1) expression, which resulted in a concomitant increase in E-cadherin levels.
Conclusion The data from the current study demonstrated that miR-200c targeted the expression of the cell migration and invasion regulator ZEB1 and that the over-expression of miR-200c suppressed bladder cancer cell migration and invasion ability, indicating that miR-200c possesses an anti-tumor progression function in bladder cancer.