bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improvement of the mechanism of lapping with a free abrasive by using a silicate composition
Authors: Makarov Volodymyr , Makarova Tamara , Vynogradov Мykola , Mastepan Sergey , Savenok Dmytro , Levadnyi Oleksandr 
Published: February 2024

The results of an experimental study are presented that explain and confirm the mechanism of lapping friction surfaces with a silicate abrasive composition.
It is shown that the stability of the silicate lapping paste over time can be achieved by introducing ferric trichloride (FeCl3), which in this case is a thickener of liquid glass and also has high hygroscopic properties. The adhesive properties of the silicate paste are improved by the addition of lubricant 1-13. This grease was chosen due to its water solubility. To increase the abrasive ability of the silicate paste, an abrasive powder was introduced.
It was found that the lapping performance of the silicate composition and the quality of surfaces are higher than when treated with the «KT» paste, which is currently used for lapping automobile engine valves. Based on the results of the study, the mechanism of lapping friction surfaces with a silicate paste is presented. The mutual movement of the surfaces results in cutting and scratching of the highest peaks of the bumps by the abrasive grains. When silicon oxide (SiO2) is added to the abrasive material, its particles are coated with silicon oxide. This is because liquid glass solutions have a high adhesive force and low surface tension. At the points of contact between the abrasive particles, the temperature rises, and since there is SiO2 around the abrasive, when the latter enters the contact zone, amorphous silica (SiO2) is formed. Since the abrasive grains are coated with a silicon oxide film, SiO2 penetrates into the cavities of micro-irregularities and adheres to the surface under repeated exposure to the abrasive. Thus, the surface to be treated is saturated with silicon oxide, which leads to an increase in its quality after grinding with a silicate composition.
It has been proven that high surface quality is formed by amorphous silica. To confirm this mechanism, chemical and X-ray spectral analyses of the samples were performed, which showed the presence of SiO2 on the treated surface and a "strong bond" of silicon compounds with the metal surface layer.
It was found that the high quality of the surface is also due to the shape of abrasive particles and wear products. It has been confirmed that with the variable movement of surfaces relative to each other, abrasive grains take on a new position each time. At the same time, they are worn from all sides and acquire a rounded shape, and are simultaneously enveloped by a SiO2 foil.
Theoria Speaks Back
Authors: Hamilton Lawrence , Piper Laurence 
Published: February 2024

Abstract
In this interview, the previous editor-in-chief of Theoria, Lawrence Hamilton, describes the evolution of Theoria to become a journal with more Southern political theory scholars and ideas, and how this was inspired by the limitations of Northern theory alone in understanding real world political problems in South Africa especially. He traces the evolution of this thought in becoming a more ‘decolonial’ type thinker through his own work, and how this intersected with Theoria's focus, with specific reference to special issues of the journal including ‘Freedom and Power’ in 2013, ‘Empire and Economics’ in 2016 and a series of African-focussed editions in 2018, 2019 and 2021. At the heart of this lived experienced of intellectual development is a validation of the importance of context-based theory and theorising that is nevertheless still engaged with northern thought and global issues. This intellectual history helps clarify Theoria's current substantive focus.
A systematic review on effectiveness, protection, and long-term preservation of vaccinations against COVID-19
Authors: Sen Sheuli , Prusty Pradip Kumar , Rawat Anurag , Gurajala Swathi , Jyothikiran H. , Rathi R. K. 
Published: February 2024

Researchers found that the affected over hundred million individuals across all continents, during the first season of the pandemic. To stop the worldwide epidemic, which has already claimed over 500,000 people in the US, widespread communal immunization is necessary. To protect themselves from the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2), at least 70 to 80 percent of persons must take precautions, because they have been unwell or because they have COVID-19 infections. The United States Food and Drug Administration also called FDA, approved that, in December on that year, the first two vaccinations were authorized for use in life-threatening situations. These vaccines are created by Pfizer/BioNTech and Moderna using the mRNA vaccination technology. High effectiveness rates of 94–95% after two interval dosages have been observed in reported safety and effectiveness studies, along with the minimal reduced chance of complications and undesirable consequences. Considering the rate of vaccine development and uncertain potential long-term detrimental consequences, there has been strong resistance in all countries to mRNA vaccines. In this research, we examined the efficacy of immunizations against covid-19, including their ability to provide protection and last for an extended period. Achieving herd immunity on a global scale is crucial in containing the pandemic, but vaccine hesitancy and limited access to vaccines continue to pose challenges. To develop herd immunity and stop spreading of the virus, it is crucial to keep up with public health precautions and step-up vaccination campaigns worldwide.
Risk Factors Associated with Colorectal Cancer at Abdoel Moeloek Regional General Hospital, Lampung Province
Authors: Mustofa Syazili , Harahap Andika Ridwan Nugraha 
Published: February 2024

Colorectal cancer is a malignant neoplasm originating or growing in the colon and rectum, which become one of the malignant diseases with the highest prevalence in Indonesia. This research aimed to determine the association between risk factors and the incidence of colorectal cancer in RSUD Dr. H. Abdul Moeloek Bandar Lampung. This research was conducted from May to July 2018 at RSUD Dr. H. Abdul Moeloek Bandar Lampung, using the observational analytic method and a case-control design. The sample of this research consisted of 92 respondents, which was determined using the consecutive sampling technique—a measurement method used in the form of interviews and medical records. Data was processed using a statistical test with a 0.05 confidence level. The result of the Chi-square test showed that there was an association between age (p = 0.01), physical activity (p = 0.001), smoking history (p = 0.001), alcohol consumption history (p = 0.021), and diabetes Mellitus history (p = 0.012) with the incidence of colorectal cancer. There was an association between age, physical activity, smoking history, alcohol consumption history, and diabetes Mellitus history with the incidence of colorectal cancer in RSUD Dr. H. Abdul Moeloek Bandar Lampung.
Jewish Mysticism as a Form of Feminism in Early 20th Century Hungarian Jewish Literature: Anna Lesznai’s Response to Otto Weininger
Authors: Rethelyi Mari 
Published: February 2024

This article examines Anna Lesznai’s radical imagining of sex and its use for transcendental purposes that heavily rely on Jewish mystical ideas intertwined with Otto Weininger's theory of gender binarism. In her gender theory—part of feminist discourse at the turn of the twentieth century—Lesznai describes female love, using religious language and ideas from Jewish mysticism, especially those resembling Hassidic concepts, and ultimately compares sexual union to yihud- unio mystica with God. Working within the patriarchal understanding of the biological definition of gender and of the concept of "female difference," Lesznai’s feminism rooted in the belief that certain personality traits and skills are inherently gendered, but she reverses the hierarchy by placing women in the position of power, thus turning Jewish mysticism and Weininger’s gender philosophy on its head.
Pelatihan Pembuatan Animasi Sederhana Menggunakan Macromedia Flash Untuk Meningkatkan Keterampilan Siswa SMK Karya Utama Tanjungbalai
Authors: Andriyani Suci , Efendi Zulfan , Latiffani Chitra 
Published: February 2024

Abstract: Education plays an important role in quality human civilization to increase human resources globally. This development reflects the close relationship between education, technological innovation and the advancement of knowledge as an integral part of society's social and intellectual evolution. The use of technology-based media is considered to provide significant benefits for both teachers and students in the process of teaching and learning activities. In this context, the education system in vocational schools should explore the potential resources or potential available around the school environment, which are relevant to the demands of the world of work. In an effort to prepare student graduates who are superior and ready to work and are able to compete in the job market, there needs to be preparation in improving the hard skills and soft skills of mature students. This service activity aims to provide assistance and training to Karya Utama Vocational School students through the use of Multimedia Technology as additional skills. The method in this activity applies training and observation to students. As a result of this activity, 85% of students were able to create simple animations using Macromedia Flash software. Keywords: animation; macromedia flash; multimedia; training.
Pemberdayaan Kelompok Tani Unggas Jaya Melalui Teknologi Monitoring Gas Amonia Dan Suhu Kandang Otomatis Berbasis IoT
Authors: Risald Risald , Baso Budiman , Ullu Hevi Herlina , Lisnahan Charles Venirius 
Published: February 2024

The Poultry Jaya farmer group is in the city of Kefamenanu, the native chicken farming system of the Jaya Poultry Group is still conventional. One of the main problems faced by this group is the lack of monitoring and controlling the temperature of the cage as well as monitoring the ammonia gas produced by chicken droppings. Temperature and ammonia gas levels have a major impact on chicken growth and health. To overcome this problem, it is necessary to implement Internet of Things (IoT) technology integrated with Android applications. This technology allows automatic and periodic monitoring of cage temperature and ammonia gas levels. Farmers can access information via the Android app and take necessary action if significant changes occur. This community service aims to build tools and systems for automatic temperature control and IoT-based ammonia levels integrated with Android, as well as introducing technology and providing training and assistance to the Unggas Jaya farmer group regarding IoT technology in chicken coop management. With the existence of IoT technology, it is hoped that the behavior patterns of farmers will change to become more modern and efficient. This technology can help improve poultry farming performance, reduce risks, and provide convenience in cage management so that it will bring positive changes to the productivity and welfare of farmers. Keywords: Poultry Jaya farmer group; chicken coop; Internet of Things (IoT)
Bibliometric analysis of intestinal microbiota and lung diseases
Authors: Sun Weiting , Zhou Tong , Ding Peng , Guo Liuxue , Zhou Xiujuan , Long Kunlan 
Published: February 2024

BackgroundIncreasing evidence suggests a close association between the intestinal microbiome and the respiratory system, drawing attention to studying the gut-lung axis. This research employs bibliometric methods to conduct a visual analysis of literature in the field of intestinal microbiota and lung diseases over the past two decades. It offers scientific foundations for research directions and critical issues in this field.MethodsWe retrieved all articles on intestinal microbiota and lung diseases from the SCI-Expanded of WoSCC on October 25, 2023. The analysis included original articles and reviews published in English from 2011 to 2023. We utilized Python, VOSviewer, and CiteSpace to analyze the retrieved data visually.ResultsA total of 794 publications were analyzed. China ranked first in the number of publications, while the United States had the highest citations and H-index. Jian Wang was the most prolific author. Zhejiang University was the institution with the highest number of publications. Frontiers in Microbiology was the journal with the most publications. Author keywords appearing more than 100 times included “intestinal microbiota/microbiome”, “microbiota/microbiome”, and “gut-lung axis”.ConclusionThe correlation and underlying mechanisms between intestinal microbiota and lung diseases, including asthma, COPD, lung cancer, and respiratory infections, remain hot topics in research. However, understanding the mechanisms involving the gut-lung axis is still in its infancy and requires further elucidation.
Urinary miR-185-5p is a biomarker of renal tubulointerstitial fibrosis in IgA nephropathy
Authors: Duan Zhi-Yu , Bu Ru , Liang Shuang , Chen Xi-Zhao , Zhang Chun , Zhang Qiu-Yue , Li Ji-Jun , Chen Xiang-Mei , Cai Guang-Yan 
Published: February 2024

BackgroundFor IgA nephropathy (IgAN), tubular atrophy/interstitial fibrosis is the most important prognostic pathological indicator in the mesangial and endocapillary hypercellularity, segmental sclerosis, interstitial fibrosis/tubular atrophy, and presence of crescents (MEST-C) score. The identification of non-invasive biomarkers for tubular atrophy/interstitial fibrosis would aid clinical monitoring of IgAN progression and improve patient prognosis.MethodsThe study included 188 patients with primary IgAN in separate confirmation and validation cohorts. The associations of miR-92a-3p, miR-425-5p, and miR-185-5p with renal histopathological lesions and prognosis were explored using Spearman correlation analysis and Kaplan-Meier survival curves. Bioinformatics analysis and dual luciferase experiments were used to identify hub genes for miR-185-5p. The fibrotic phenotypes of tubular epithelial cells were evaluated in vivo and in HK-2 cells.ResultsmiRNA sequencing and cohort validation revealed that the expression levels of miR-92a-3p, miR-425-5p, and miR-185-5p in urine were significantly increased among patients with IgAN; these levels could predict the extent of tubular atrophy/interstitial fibrosis in such patients. The combination of the three biomarkers resulted in an area under the receiver operating characteristic curve of 0.742. The renal prognosis was significantly worse in the miR-185-5p high expression group than in the low expression group (P=0.003). Renal tissue in situ hybridization, bioinformatics analysis, and dual luciferase experiments confirmed that miR-185-5p affects prognosis in patients with IgAN mainly by influencing expression of the target gene tight junction protein 1 (TJP1) in renal tubular epithelial cells. In vitro experiment revealed that an miR-185-5p mimic could reduce TJP1 expression in HK-2 cells, while increasing the levels of α-smooth muscle actin, fibronectin, collagen I, and collagen III; these changes promoted the transformation of renal tubular epithelial cells to a fibrotic phenotype. An miR-185-5p inhibitor can reverse the fibrotic phenotype in renal tubular epithelial cells. In a unilateral ureteral obstruction model, the inhibition of miR-185-5p expression alleviated tubular atrophy/interstitial fibrosis.ConclusionUrinary miR-185-5p, a non-invasive biomarker of tubular atrophy/interstitial fibrosis in IgAN, may promote the transformation of renal tubular epithelial cells to a fibrotic phenotype via TJP1.
Extracellular vesicles in the treatment of oxidative stress injury: global research status and trends
Authors: Zhang Wenwen , Gan Bin , Wang Tingyu , Yang Xiangjie , Xue Yuanye , Zhong Yuanqing , He Xintong , Peng Xinsheng , Zhou Yanfang , Cheng Xiaoyan 
Published: February 2024

Objective: The aim of this study was to conduct a bibliometric analysis of the literature on “Extracellular Vesicles in the Treatment of Oxidative Stress Injury” and to reveal its current status, hot spots and trends.Methods: The relevant literature was obtained from the Web of Science Core Collection (WoSCC) on 29 April 2023. We performed clustering and partnership analysis of authors, institutions, countries, references and keywords in the literature through CiteSpace software and the bibliometric online analysis platform and mapped the relevant knowledge maps.Results: A total of 1,321 relevant publications were included in the bibliometric analysis, with the number of publications in this field increasing year by year. These included 944 “articles” and 377 “reviews”. The maximum number of publications published in China is 512, and the maximum number of highly cited publications published in the United States is 20. Based on CiteSpace, the country collaboration network map shows close and stable collaboration among high-productivity countries. Based on WoSCC, there are 1706 relevant research institutions and 119 highly cited elite institutions, among which Kaohsing Chang Gung Men Hosp has the most extensive influence. Studies related to “Extracellular Vesicles in the Treatment of Oxidative Stress Injury” have been published in 548 journals. The keywords of the publications show the main research areas and breakthroughs. Based on WoSCC, the keywords of the research area “Extracellular Vesicles in the Treatment of Oxidative Stress Injury” were found to be as follows: exosome(s), extracellular vesicle(s), oxidative stress, inflammation, mesenchymal stem cells, apoptosis, microRNA (miRNA), mitochondria, biomarker, autophagy, angiogenesis and Alzheimer’s disease. Analysis showed that “mesenchymal stem cells”, “microRNA”, “autophagy”, “histology” and “therapeutic” emerged as highly explosive keywords.Conclusion: This study is the first to use visual software and data mining to assess the literature in the field of “Extracellular Vesicles in the Treatment of Oxidative Stress Injury”. The research history, research status and direction in this field provide a theoretical basis for its scientific research.
Quantitative double echo steady state T2 mapping of upper extremity peripheral nerves and muscles
Authors: Campbell Gracyn J. , Sneag Darryl B. , Queler Sophie C. , Lin Yenpo , Li Qian , Tan Ek T. 
Published: February 2024

IntroductionT2 mapping can characterize peripheral neuropathy and muscle denervation due to axonal damage. Three-dimensional double echo steady-state (DESS) can simultaneously provide 3D qualitative information and T2 maps with equivalent spatial resolution. However, insufficient signal-to-noise ratio may bias DESS-T2 values. Deep learning reconstruction (DLR) techniques can reduce noise, and hence may improve quantitation of high-resolution DESS-T2. This study aims to (i) evaluate the effect of DLR methods on DESS-T2 values, and (ii) to evaluate the feasibility of using DESS-T2 maps to differentiate abnormal from normal nerves and muscles in the upper extremities, with abnormality as determined by electromyography.Methods and resultsAnalysis of images from 25 subjects found that DLR decreased DESS-T2 values in abnormal muscles (DLR = 37.71 ± 9.11 msec, standard reconstruction = 38.56 ± 9.44 msec, p = 0.005) and normal muscles (DLR: 27.18 ± 6.34 msec, standard reconstruction: 27.58 ± 6.34 msec, p &lt; 0.001) consistent with a noise reduction bias. Mean DESS-T2, both with and without DLR, was higher in abnormal nerves (abnormal = 75.99 ± 38.21 msec, normal = 35.10 ± 9.78 msec, p &lt; 0.001) and muscles (abnormal = 37.71 ± 9.11 msec, normal = 27.18 ± 6.34 msec, p &lt; 0.001). A higher DESS-T2 in muscle was associated with electromyography motor unit recruitment (p &lt; 0.001).DiscussionThese results suggest that quantitative DESS-T2 is improved by DLR and can differentiate the nerves and muscles involved in peripheral neuropathies from those uninvolved.
Global burden of maternal disorders attributable to malnutrition from 1990 to 2019 and predictions to 2035: worsening or improving?
Authors: Xu Tongtong , Dong Chenxian , Shao Jianjiang , Huo Chaojing , Chen Zuhai , Shi Zhengyang , Yao Teng , Gu Chenyang , Wei Wanting , Rui Dongsheng , Li Xiaoju , Hu Yunhua , Ma Jiaolong , Niu Qiang , Yan Yizhong 
Published: February 2024

Background and aimsMaternal malnutrition is a major global public health problem that can lead to serious maternal diseases. This study aimed to analyze and predict the spatio-temporal trends in the burden of maternal disorders attributable to malnutrition, and to provide a basis for scientific improvement of maternal malnutrition and targeted prevention of maternal disorders.MethodsData on maternal disorders attributable to malnutrition, including number of deaths, disability-adjusted life years (DALYs), population attributable fractions (PAFs), age-standardized mortality rates (ASMRs), and age-standardized DALY rates (ASDRs) were obtained from the Global Burden of Disease Study 2019 to describe their epidemiological characteristics by age, region, year, and type of disease. A log-linear regression model was used to calculate the annual percentage change (AAPC) of ASMR or ASDR to reflect their temporal trends. Bayesian age-period-cohort model was used to predict the number of deaths and mortality rates to 2035.ResultsGlobal number of deaths and DALYs for maternal disorders attributable to malnutrition declined by 42.35 and 41.61% from 1990 to 2019, with an AAPC of –3.09 (95% CI: −3.31, −2.88) and –2.98 (95% CI: −3.20, −2.77) for ASMR and ASDR, respectively. The burden was higher among younger pregnant women (20–29 years) in low and low-middle socio-demographic index (SDI) regions, whereas it was higher among older pregnant women (30–39 years) in high SDI region. Both ASMR and ASDR showed a significant decreasing trend with increasing SDI. Maternal hemorrhage had the highest burden of all diseases. Global deaths are predicted to decline from 42,350 in 2019 to 38,461 in 2035, with the ASMR declining from 1.08 (95% UI: 0.38, 1.79) to 0.89 (95% UI: 0.47, 1.31).ConclusionMaternal malnutrition is improving globally, but in the context of the global food crisis, attention needs to be paid to malnutrition in low SDI regions, especially among young pregnant women, and corresponding measures need to be taken to effectively reduce the burden of disease.
Efficacy and safety of enzyme replacement therapy with alglucosidase alfa for the treatment of patients with infantile-onset Pompe disease: a systematic review and metanalysis
Authors: Dornelles A. D. , Junges A. P. P. , Krug B. , Gonçalves C. , de Oliveira Junior H. A. , Schwartz I. V. D. 
Published: February 2024

IntroductionPompe disease (PD) is a glycogen disorder caused by the deficient activity of acid alpha-glucosidase (GAA). We sought to review the latest available evidence on the safety and efficacy of recombinant human GAA enzyme replacement therapy (ERT) for infantile-onset PD (IOPD).MethodsWe systematically searched the MEDLINE (via PubMed) and Embase databases for prospective clinical studies evaluating ERT for IOPD on pre-specified outcomes. Meta-analysis was also performed.ResultsOf 1,722 articles identified, 16 were included, evaluating 316 patients. Studies were heterogeneous and with very low certainty of evidence for most outcomes. A moderate/high risk of bias was present for most included articles. The following outcomes showed improvements associated with alglucosidase alfa, over natural history of PD/placebo, for a mean follow-up of 48.3 months: left ventricular (LV) mass {mean change 131.3 g/m2 [95% confidence interval (CI) 81.02, 181.59]}, time to start ventilation (TSV) [HR 0.21 (95% CI: 0.12, 0.36)], and survival [HR 0.10 (95% CI: 0.05, 0.19)]. There were no differences between the pre- and post-ERT period for myocardial function and psychomotor development. Adverse events (AEs) after ERT were mild in most cases.ConclusionOur data suggest that alglucosidase alfa potentially improves LV mass, TSV, and survival in IOPD patients, with no important safety issues.Systematic Review RegistrationPROSPERO identifier (CRD42019123700).