bluuebunny/crossref_metadata_2025_split huggingface dataset:
Posible inducción de resistencia sistémica a Lasiodiplodia theobromae en aguacate (Persea americana Mill.) en condiciones semicontroladas en La Molina
Authors: Jimenez-Ariza Nery Veronica , Soto-Heredia Jose Miguel , Casas-Díaz Andrés Virgilio , Aragón-Caballero Liliana María 
Published: November 2023

La producción y exportación de frutos de palta, cultivar Hass, ha crecido exponencialmente en los últimos años en el Perú, sin embargo, se ha observado una alta incidencia de síntomas como muerte regresiva, cancros en ramas de la planta y pudrición del fruto que afectan la producción óptima del cultivo y la calidad del fruto. Estos síntomas son generados principalmente por el hongo Lasiodiplodia theobromae, cuyo control está limitado a unos pocos principios activos que tienden a generar resistencia al patógeno. La presente investigación tuvo como objetivo evaluar el efecto inductor de resistencia en el control de Lasiodiplodia theobromae en aguacate (Persea americana) cultivar Hass de cinco bioproductos: ProtecSea, Barrera, Timorex Gold, T 22, Vacun Q Pro y agua como tratamiento control, con un total de 6 tratamientos con 4 repeticiones, 3 árboles de aguacate por repetición. Se utilizaron árboles de aguacate cultivar Hass de un año de edad. Los tratamientos se aplicaron tres veces mediante drench a intervalos de diez días. Cinco días después de la última aplicación se inoculó L. theobromae en los aguacateros cultivar ‘Hass’ y 40 días después de la inoculación se evaluaron los parámetros: longitud de la lesión de la enfermedad, porcentaje de materia seca de las raíces y hojas, y longitud de las raíces. Se observó que los tratamientos, a excepción del tratamiento T1 (Control), redujeron la longitud de la lesión de la enfermedad infectada por L. theobromae en el interior del tallo. El tratamiento T6 (T.22) dio lugar a un mayor porcentaje de materia seca radicular (46,52 %) en comparación con el tratamiento testigo (41,21 %). Por otro lado, no hubo diferencias significativas en el contenido de materia seca foliar entre los tratamientos. Adicionalmente, se observó que el tratamiento T2 (ProtecSea) reportó una longitud de raíz de 56.80 cm, seguido del tratamiento T6 (T.22) con 54.90 cm. Estos resultados son importantes para continuar con las investigaciones para inducir resistencia sistémica en las plantas.
Systematic Analysis of Tumor Stem Cell-related Gene Characteristics
to Predict the PD-L1 Immunotherapy and Prognosis of Gastric
Cancer
Authors: Wang Chenchen , Chen Ying , Zhou Ru , Yang Ya’nan , Fang Yantian 
Published: November 2023

Aims:
We aimed to develop a prognostic model with stemness-correlated
genes to evaluate prognosis and immunotherapy responsiveness in gastric cancer (GC).

Background:
Tumor stemness is related to intratumoral heterogeneity, immunosuppression,
and anti-tumor resistance. We developed a prognostic model with stemness-correlated
genes to evaluate prognosis and immunotherapy responsiveness in GC.

Objective:
We aimed to develop a prognostic model with stemness-correlated genes to
evaluate prognosis and immunotherapy responsiveness in GC.

Methods:
We downloaded single-cell RNA sequencing (scRNA-seq) data of GC patients
from the Gene-Expression Omnibus (GEO) database and screened GC stemness-
related genes using CytoTRACE. We characterized the association of tumor stemness
with immune checkpoint blockade (ICB) and immunity. Thereafter, a 9-stemness
signature-based prognostic model was developed using weighted gene co-expression network
analysis (WGCNA), univariate Cox regression analysis, and the least absolute
shrinkage and selection operator (LASSO) regression analysis. The model predictive value
was evaluated with a nomogram.

Results:
Early GC patients had significantly higher levels of stemness. The stemness
score showed a negative relationship to tumor immune dysfunction and exclusion
(TIDE) score and immune infiltration, especially T cells and B cells. A stemness-based
signature based on 9 genes (ERCC6L, IQCC, NKAPD1, BLMH, SLC25A15, MRPL4,
VPS35, SUMO3, and CINP) was constructed with good performance in prognosis prediction,
and its robustness was validated in GSE26942 cohort. Additionally, nomogram
and risk score exhibited the most powerful ability for prognosis prediction. High-risk patients
exhibited a tendency to develop immune escape and low response to PD-L1 immunotherapy.

Conclusion:
We developed a stemness-based gene signature for prognosis prediction
with accuracy and reliability. This signature also helps clinical decision-making of immunotherapy
for GC patients.
Cognitive Behavioral Therapy for AIDS Prevention among College Students in China: A Cluster Randomized Controlled Trial
Authors: Lei Yumeng , Xiang Xiaochen , Chen Lingxue , He Mingxin , Li Simin , Wang Qiang 
Published: November 2023

Background::
Acquired immune deficiency syndrome (AIDS) is a serious worldwide
public health problem and has become the focus of prevention and control in China, while the student
population is the key population for AIDS prevention.

Objective::
The purpose of this study was to investigate the effects of cognitive behavioral therapy
(CBT) on college students' AIDS-related cognitions, attitudes, and behaviors, and to find programmatic
strategies for AIDS prevention in terms of changing college students' cognitions and behaviors.

Methods::
In a cluster randomized controlled trial, 233 undergraduate students were assigned to
the CBT group (CBT-based intervention, n=92), the TAU group (treatment as usual, n=72), and
the CON group (no intervention, n=59). AIDS-related knowledge, attitudes, and behaviors of participants
were assessed at pre-intervention, post-intervention, and follow-up.

Results::
After one month of the study, AIDS-related knowledge, attitudes, and behaviors improved
in both the TAU and CBT groups, while there were no significant changes in the CON
group. The intervention effect was more significant and sustainable in the CBT group compared
to the TAU group.

Conclusions::
The application of CBT in AIDS prevention among college students is feasible, acceptable,
and effective. CBT can increase the level of knowledge about AIDS, improve AIDS-related
attitudes, and increase willingness to use condoms. CBT is expected to replace traditional
health education as an innovative tool for AIDS prevention because of its long-lasting and efficacious
nature.
An MRI-only Three-dimensional Cephalometry Protocol based on the
Integrated and Modular Architecture of the Human Head
Authors: Jiang Xiling , Pei Jun , Liu Jianwei , Liao Xu , Jia Fucang 
Published: November 2023

Background::
Currently, three-dimensional cephalometry measurements are mainly based on cone beam computed tomography (CBCT), which has limitations of ionizing radiation, lack of soft tissue information, and lack of standardization of median sagittal plane establishment.

Objectives::
This study investigated magnetic resonance imaging (MRI)-only based 3D cephalometry measurement based on the integrated and modular characteristics of the human head.

Methods::
Double U-Net CycleGAN was used for CT image synthesis from MRI. This method enabled the synthesis of a CT-like image from MRI and measurements were made using 3D slicer registration and fusion.

Results::
A protocol for generating and optimizing MRI-based synthetic CT was described and found to meet precision requirements of 3D head measurement using MRI midline positioning methods reported in neuroscience to establish the median sagittal plane. An MRI-only reference frame and coordinate system were established enabling an MRI-only cephalometric analysis protocol that combined the dual advantages of soft and hard tissue display. The protocol was devised using data from a single volunteer and validation data from a larger sample remains to be collected.

Conclusion::
The reported method provided a new protocol for MRI-only cephalometric analysis of craniofacial growth and development, malformation occurrence, treatment planning and outcomes.
Implementation of flipped learning with flipbook media assistance on learning outcomes and critical thinking abilities
Authors: Sudiarti Diah , Ashilah Nashlul Muflihatul , Nurjanah Umi 
Published: November 2023

This research was conducted as a sort of classroom action research with two learning cycles to examine whether flipped learning aided by flipbook media may enhance students' cognitive learning outcomes and critical thinking skills. This research's population consisted of tenth-grade Madrasah Aliyah Al Misri Curahmalang students for the academic year 2021-2022. Methods for collecting data include interviews, tests, observations, and documentation. The classical completeness of cognitive learning outcomes increased from 19% in the first cycle to 97% in the second cycle, according to the research findings. Whereas critical thinking abilities were acquired in the first cycle, just one student met critical criteria. In contrast, six students exceeded crucial criteria, and twenty students exceeded critical criteria in the second cycle. Based on the analyzed research findings, it is possible to conclude that flipped learning aided by flipbook media can enhance students' cognitive learning outcomes and critical thinking skills.
Khảo sát thành phần loài tuyến trùng ký sinh cam quýt ở đồng bằng sông Cửu Long
Authors: Nguyễn Bá Phú , Đinh Thị Hồng Duyên , Nguyễn Quốc Sĩ , Lê Thị Tú Anh 
Published: November 2023

Nghiên cứu được thực hiện nhằm xác định mật số và thành phần loài tuyến trùng ký sinh trên cam quýt ở đồng bằng sông Cửu Long gồm bưởi da xanh (Citrus maxima) (Bến Tre), bưởi Năm Roi (Citrus maxima) và hạnh (Citrofortunella macrocarpa (B.) Wi.) (Vĩnh Long), cam mật (Citrus sinensis (L.) Osb.) (Hậu Giang), cam soàn (Citrus sinensis (L.) cv. Soan) và quýt hồng (Citrus nobilis var. chrysocarpa Lamk.) (Đồng Tháp), chanh Tàu (Citrus limonia Osb.) (Tiền Giang). Kết quả xác định được 7 loài ký sinh gồm: Pratylenchus sp., Tylenchulus semipenetrans, Rotylenchulus sp., Tylenchus sp., Helicotylenchus sp., Tylenchorhynchus sp. và Criconemella sp.. Mật số tuyến trùng trung bình trong đất (con/kg đất) là Tylenchulus semipenetrans (1.813), Pratylenchus sp. (97), Tylenchus sp. (48), Helicotylenchus sp. (46), Tylenchorhynchus sp. (17), Rotylenchulus sp. (10), Criconemella sp. (0,2); ở rễ (con/g rễ): Pratylenchus sp. (24) và Tylenchulus semipenetrans (6). Thành phần ký sinh trong đất là Tylenchulus semipenetrans (89,1%), Pratylenchus sp. (4,76%), Tylenchus sp. (2,59%), Helicotylenchus sp. (2,25%), Tylenchorhynchus sp. (0,83%), Rotylenchulus sp. (0,48%) và Criconemella sp. (0,01%); ở rễ: Pratylenchus sp. (83,1%) và Tylenchulus semipenetrans (16,9%).
PARTISIPASI MASYARAKAT DALAM MENGURANGI RISIKO BANJIR DI KELURAHAN PONDOK PINANG KECAMATAN KEBAYORAN LAMA KOTA JAKARTA SELATAN
Authors: Hilmy Reza Nabil , Aly Sya'ban Mohammad Balya 
Published: November 2023

Abstract: Floods that occur in the capital city of Jakarta generally occur because of the large number of settlements that stand along the riverbanks. The width of the river is getting narrower and river sedimentation is occurring. On the other hand, the lack of green open land and lack of public awareness in preserving the environment is one of the causes of flooding in the capital, Jakarta. This research aims to determine the level of community participation in reducing the risk of flooding in Pondok Pinang Village, Kebayoran Lama District, South Jakarta City. The research method used is a descriptive research method with a quantitative approach. Based on the calculation results, the percentage obtained is 94% that community participation can reduce the risk of flooding in Pondok Pinang Village, Kebayoran Lama District, South Jakarta City. The results of this research show that the people of Pondok Pinang Village, Kebayoran Lama District have a very important role in reducing flood risk. Forms of community participation include waste management, cleaning drainage channels, making biopores in each yard of the house, as well as actively participating in education related to flood risk management.Keywords: Participation; Public; Flood; Environment; River.Abstrak: Banjir yang terjadi di Ibukota Jakarta umumnya terjadi karena banyaknya permukiman yang berdiri di sepanjang bantaran sungai. Lebar sungai yang semakin menyempit serta sedimentasi sungai. Di sisi lain, kurangnya lahan terbuka hijau dan kurangnya kesadaran masyarakat dalam menjaga kelestarian lingkungan menjadi salah satu penyebab terjadinya banjir di Ibukota Jakarta. Penelitian ini bertujuan untuk mengetahui tingkat partisipasi masyarakat dalam mengurangi risiko banjir di Kelurahan Pondok Pinang, Kecamatan Kebayoran Lama, Kota Jakarta Selatan. Metode penelitian yang digunakan adalah metode penelitian deskriptif dengan pendekatan kuantitatif. Berdasarkan hasil perhitungan, persentase yang diperoleh adalah sebesar 94% partisipasi masyarakat dapat mengurangi risiko banjir di Kelurahan Pondok Pinang, Kecamatan Kebayoran Lama, Kota Jakarta Selatan. Hasil penelitian ini menunjukan bahwa masyarakat Kelurahan Pondok Pinang Kecamatan Kebayoran Lama memiliki peran yang sangat penting terhadap pengurangan risiko banjir. Bentuk partisipasi masyarakat yang dilakukan di antaranya pengaturan sampah, perbersihan saluran drainase, pembuatan biopori di tiap halaman rumah, serta ikut aktif mengikut penyuluhan yang berkaitan dengan penanganan risiko banjir.Kata Kunci: Partisipasi; Masyarakat; Banjir; Lingkungan; Sungai.
ANALISIS LAGRANGIAN NULL NONSTANDAR DAN FUNGSI GAUGE UNTUK HUKUM INERSIA NEWTON : SEBUAH REVIEW
Authors: Ambot Amelia A.P , Lalus Herry F. , Yudhawardana Hartoyo 
Published: November 2023

This paper describes a review of a journal entitled 'Nonstandard Null Lagrangians and Gauge Functions for Newtonian Law of Inertia' which discusses Nonstandard Lagrangian Null solutions for Newton's Law of Inertia. The purpose of this study is to present in detail the Lagrangian Formalism method for generating Nonstandard Lagrangian Null and its Gauge function for Newton's Law of Inertia, as well as the role of action invariant in generating Lagrangian Null and Exact Gauge functions, by deriving a one-dimensional oscillator arm using the basic Lagrangian equations. The Nonstandard Null Lagrangian is derived from the Nonstandard Lagrangian, then the two Lagrangian Null are entered into the action invariant to make it Exact, after the Nonstandard Lagrangian Null is declared Exact, it is substituted into which represents Newton's Law of Inertia. The results of this research show that an Exact Nonstandard Lagrangian Null can be generated by making the Gauge Function Invariant, so that the first Nonstandard Lagrangian Null and Gauge Function for Newton's Law of Inertia are obtained.
Preparation and characterization of carbon nanotube films and fibers for determining the thermal conductivity at different temperatures
Authors: Brown Christopher , Chen Junjie 
Published: November 2023

Novel chemical, electrical, and mechanical properties absent in other
materials have been discovered in carbon nanotubes. Pristine carbon
nanotubes are inert to most chemicals and need to be grafted with
surface functional groups to increase their chemical reactivity and add
new properties. The increasing popularity of carbon nanotubes has
created a demand for greater scientific understanding of the
characteristics of thermal transport in nanostructured materials.
However, the effects of impurities, misalignments, and structure factors
on the thermal conductivity of carbon nanotube films and fibers are
still poorly understood. Carbon nanotube films and fibers were produced,
and the parallel thermal conductance technique was employed to determine
the thermal conductivity. The effects of carbon nanotube structure,
purity, and alignment on the thermal conductivity of carbon films and
fibers were investigated to understand the characteristics of thermal
transport in the nanostructured material. The importance of bulk density
and cross-sectional area was determined experimentally. The results
indicated that single-walled carbon nanotube films and fibers generally
have high thermal conductivity. The presence of non-carbonaceous
impurities degrades the thermal performance due to the low degree of
bundle contact. The prepared carbon nanotube films and fibers are very
efficient at conducting heat. The structure, purity, and alignment of
carbon nanotubes play a fundamentally important role in determining the
heat conduction properties of carbon films and fibers. The thermal
conductivity may present power law dependence with temperature. The
specific thermal conductivity decreases with increasing bulk density.
The specific thermal conductivity of carbon nanotube fibers is
significantly higher than that of carbon nanotube films due to the
increased degree of bundle alignment. At room temperature, a maximum
specific thermal conductivity is obtained but Umklapp scattering occurs.
Keywords: Thermal properties; Preparation; Carbon films; Carbon
fibers; Characterization; Thermal conductivity
Efficacy and Selectivity of Different Herbicides on the Transplanted Late Boro Rice under the Lateritic Soil of West Bengal
Authors: Gupta Rahul Kumar , Ghosh Pritam , Aparna Mahanti , Bharti Ruchi , Pramanik Kalipada 
Published: November 2023

A field experiment was conducted during the late boro seasons (January–May) of 2018 and 2019 to assess the impact of herbicides on rice growth, yield and weed control in transplanted rice in the Agricultural Farm of Palli Siksha Bhavana (Institute of Agriculture), Visva-Bharati University, Sriniketan, West Bengal, India. There were eight different treatments consisting of pretilachlor 50 EC @ 500 g ha-1 at 3 DAT, pyrazosulfuron ethyl 10 WP @ 30 g ha-1 at 3 DAT, ethoxysulfuron 15 WDG @ 15 g ha-1 at 10 DAT, penoxsulam 21.7 SC @ 22.5 g ha-1 at 12 DAT, bispyribac-sodium 10 SC @ 25 g ha-1 at 15 DAT, hand weeding at 20 and 40 DAT, weed-free check and weedy check. Results from the pooled analysis of both the years revealed that pyrazosulfuron ethyl 30 g ha-1 and pretilachlor at 500 g ha-1 resulted in lower weed population and dry weight; higher plant height, number of tillers m-2, dry matter accumulation, leaf area index; grain and straw yield (5.98 and 7.81 t ha-1 and 5.81 and 7.62 t ha-1 respectively). The lowest weed index was registered by pyrazosulfuron ethyl 30 g ha-1 and pretilachlor at 500 g ha-1 and was superior to all other herbicidal treatments. Yield loss due to weeds infestation throughout the crop season was to the extent of 54.33%. Thus, pyrazosulfuron ethyl 30 g ha-1 and pretilachlor at 500 g ha-1 as pre-emergence may be recommended for effective weed control in transplanted late boro rice.
Validação de conteúdo de um sistema informatizado de notificação de eventos adversos
Authors: Braga Cristina Spena , Cunha Karinne Cristinne da Silva , Pereira Quézia Vilela da Costa 
Published: November 2023

Construir e validar um protótipo de Sistema Informatizado de Notificação Voluntária de Incidentes. Estudo metodológico que utilizou a técnica Delphi para a avaliação da opinião de juízes especialistas na temática, a escala de usabilidade SUS para avaliação do sistema e a escala Likert de cinco pontos para avaliar a concordância dos juízes especialistas quanto aos critérios. A validação de usabilidade teve um escore médio total de 78,1 com valor mínimo de 25 e máximo de 95. Para a validação de conteúdo o coeficiente de Kappa ponderado (K) apontou uma concordância pobre entre os juízes, com Kappa = 0,07, índice de concordância de 0,04 - 0,11 e p=4,93. O protótipo do Sistema Informatizado de Notificação Voluntária de Incidentes foi validado quanto à usabilidade, sendo de fácil uso e sua aplicabilidade factível, classificado como excelente.
Descritores: Eventos Adversos, Sistemas de Informação, Saúde Pública, Gestão de Risco.

Content validation of a computerized adverse event reporting system
Abstract: To build and validate a prototype of a Computerized System for Voluntary Reporting of Incidents. Methodological study that used the Delphi technique to assess the opinion of specialist judges on the subject, the SUS usability scale to assess the system and the five-point Likert scale to assess the agreement of specialist judges regarding the criteria. The usability validation had a total average score of 78.1 with a minimum value of 25 and a maximum value of 95. For content validation, the weighted Kappa coefficient (K) indicated poor agreement between the judges, with Kappa = 0 .07, concordance index of 0.04 - 0.11 and p=4.93. The prototype of the Computerized System for Voluntary Notification of Incidents was validated for usability, being easy to use and its applicability feasible, classified as excelente.
Descriptors: Adverse Events, Information Systems, Public Health, Risk Management.

Validación de contenido de un sistema informatizado de notificación de eventos adversos
Resumen: Construir y validar un prototipo de Sistema Informático de Reporte Voluntario de Incidentes. Estudio metodológico que utilizó la técnica Delphi para evaluar la opinión de los jueces especialistas sobre el tema, la escala de usabilidad del SUS para evaluar el sistema y la escala Likert de cinco puntos para evaluar la concordancia de los jueces especialistas con respecto a los criterios. La validación de usabilidad tuvo un puntaje promedio total de 78,1 con un valor mínimo de 25 y un valor máximo de 95. Para la validación de contenido, el coeficiente Kappa ponderado (K) indicó poca concordancia entre los jueces, con Kappa = 0,07, índice de concordancia de 0,04 - 0,11 y p=4,93. El prototipo del Sistema Informático de Notificación Voluntaria de Incidentes fue validado en usabilidad, siendo fácil de usar y factible su aplicabilidad, clasificado como excelente.
Descriptores: Eventos Adversos, Sistemas de Información, Salud Pública, Gestión de Riesgos.
Exploring Bacterial Diversity: How Far Have We Reached?
Authors: Pandey Himani , Lal Devi 
Published: November 2023

Abstract
Many methods have been developed for studying and comparing bacterial diversity. These methods suffer from a number of drawbacks. Culture-dependent methods have a drawback that only a small number of bacteria can be cultured. Although many modifications in the traditional cultivation approach have been made, such as the use of gellan instead of agar and high throughput dilution to extinction culturing, but a large fraction of microbes still remain uncultured. Culture-independent methods were developed to explore uncultured bacterial diversity but they have their own drawbacks. PCR-based methods have biases during DNA extraction and the removal of substances that may inhibit polymerase activity during PCR and digestion with restriction enzymes. “Omics” approach, i.e., metagenomics, metatranscriptomics, and metaproteomics, aim to link bacterial community structure with function. Different combinations of methods can be used to know more precisely about the bacterial diversity. To date, no known method can reveal the exact bacterial diversity of different environments. This lacuna needs to be filled and newer methods must be developed that can help in exploring the immense bacterial diversity created by nature.