bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psychosocial and sociodemographic factors associated with gestational blood glucose levels in women attending public hospitals: Results from baseline of MAASTHI cohort
Authors: Shriyan Prafulla , Koya Srinidhi , Lobo Eunice , van Schayck Onno CP , Babu Giridhara R. 
Published: October 2023

Background
Understanding psychosocial environment is important for improving maternal and fetal health outcomes during pregnancy. We aimed to identify the association between gestational blood glucose levels and psychosocial and demographic factors in pregnant women.

Methods
In the MAASTHI pregnancy cohort in Bengaluru, we assessed depressive symptoms, and social support using validated scales at baseline in first trimester. A 2-hour 75 g oral glucose tolerance test (OGTT) was administered between 24–36 weeks of gestation. We examined the relation between psychosocial factors assessed at baseline and gestational blood glucose levels in second/third trimester using multivariate linear regression and explored association between serum cortisol and gestational blood glucose levels in subgroup samples.

Results
We found that 9% of pregnant women had depressive symptoms and 14.3% had Gestational Diabetes Mellitus (GDM). Psychosocial factors, including depressive symptoms, have a significant correlation with gestational fasting(β = 0.12, p-value<0.05) and postprandial blood sugar level(β = 0.23, p-value<0.05) and poor social support were found to have a significant association with gestational fasting blood glucose levels(β = 1.45, p-value <0.05) and postprandial blood sugar levels(β = 2.60, p-value <0.05). The sociodemographic factors such as respondent education, occupation, social and economic status were associated with gestational blood sugar after adjusting for potential confounder variables.

Conclusion
Depressive symptoms and poor social support earlier in pregnancy were significantly associated with increased gestational blood glucose levels. Early detection and recognition of modifiable psychosocial risk factors can reduce glucose intolerance during pregnancy. Evaluating the benefits of screening for psychosocial factors and timely management of gestational diabetes mellitus can be helpful in India.
Associations of frailty with partial and absolute sedentary behaviours among older adults: A STROBE-compliant analysis of modifiability by gender and age
Authors: Asiamah Nestor , Khan Hafiz T. A. , Yarfi Cosmos , Agyemang Simon Mawulorm , Arthur-Mensah Jnr Reginald , Muhonja Faith , Sghaier Sarra , Kouveliotis Kyriakos 
Published: October 2023

Background
Research shows that frailty is associated with higher sedentary behaviour, but the evidence to date regarding this association is inconclusive. This study assessed whether the above association is moderated or modified by gender and age, with sedentary behaviour measured with a more inclusive method.

Methods
This study adopted a STROBE-compliant cross-sectional design with sensitivity analyses and measures against common methods bias. The participants were community-dwelling older adults (mean age = 66 years) in two Ghanaian towns. A self-reported questionnaire was used to collect data from 1005 participants after the minimum sample size necessary was calculated. The hierarchical linear regression analysis was used to analyse the data.

Results
After adjusting for the ultimate confounders, frailty was associated with higher sedentary behaviour (β = 0.14; t = 2.93; p <0.05) as well as partial and absolute sedentary behaviour. Gender modified the above associations in the sense that frailty was more strongly associated with sedentary behaviour among women, compared with men. Age also modified the association between frailty and sedentary behaviour, which suggests that frailty was more strongly associated with higher sedentary behaviour at a higher age.

Conclusion
Sedentary behaviour could be higher at higher frailty among older adults. Frailty is more strongly associated with sedentary behaviour at a higher age and among women, compared with men.
Tejiendo latidos, ritmos y sonidos de paz
Authors: Villegas Posada José Fernando 
Published: October 2023

Esta reflexión surge en el marco proyecto “Rehabilitación y reintegración de niños, jóvenes y adultos traumatizados por la guerra para mejorar la situación social en Colombia 2021- 2023”, implementado por el programa La Paz es una Obra de Arte, en asocio con la Fundación Freunde, Amigos del Arte de Enseñar – Alemania, y con la metodología Pedagogía de Emergencia y Trauma. El proyecto implementó un proceso educativo usando prácticas sociales de las artes con jóvenes de la Comunidad Convivencial de la Escuela de Trabajo San José, de Bello-Antioquia-Colombia.
Este artículo presenta la implementación de los talleres pedagógicos del proyecto en general, con especial énfasis y profundización en la metodología propuesta desde la música. Del módulo “Escucha e Interacción Expresiva”, se expondrán tanto la secuencia didáctica, sus propósitos, intensiones y dispositivos educativos. Además, se muestran los vínculos y relaciones directas entre la música a la construcción de cultura de paz, además de exponer las contribuciones de la música a la paz personal y colectica, percibidas y expresadas por los participantes.
Recovery of Lung Function After 149 Days on Extracorporeal Membrane Oxygenation for COVID-19
Authors: Suero Orlando R. , Valluri Sri Kartik , Farias-Kovac Mario H. , Simpson Leo , Loor Gabriel , Guerra Diana M. , Diaz-Gomez Jose L. , Chatterjee Subhasis 
Published: October 2023

Abstract
This report highlights survival and the patient’s perspective after prolonged venovenous extracorporeal membrane oxygenation (ECMO) for COVID-19–related respiratory failure.
A 36-year-old man with COVID-19 presented with fever, anosmia, and hypoxia. After respiratory deterioration necessitating intubation and lung-protective ventilation, he was referred for ECMO. After 3 days of conventional venovenous ECMO, he required multiple creative cannulation configurations. Adequate sedation and recurrent bradycardia were persistent challenges. After 149 consecutive days of ECMO, he recovered native lung function and was weaned from mechanical ventilation.
This represents the longest-duration ECMO support in a survivor of COVID-19 yet reported. Necessary strategies included unconventional cannulation and flexible anticoagulation.
Short-term biological variation of serum tryptase
Authors: Madsen Anne Tranberg , Kristiansen Helle Pilgaard , Winther-Larsen Anne 
Published: October 2023

Abstract

Objectives
Serum tryptase is a biomarker of mast cell activation. Among others, it is used in the diagnosis of anaphylaxis where a significant increase during the acute phase supports the diagnosis. When evaluating changes in biomarker levels, it is of utmost importance to consider the biological variation of the marker. Therefore, the aim of this study was to evaluate the short-term biological variation of serum tryptase.

Methods
Blood samples were drawn at 9 AM three days in a row from apparently healthy subjects. On day two, additional blood samples were drawn every third hour for 12 h. The tryptase concentration was measured in serum using a fluoroenzyme immunoassay (ImmunoCAP™, Thermo Fisher Scientific). Linear mixed-effects models were used to calculate components of biological variation.

Results
In 32 subjects, the overall mean concentration of tryptase was 4.0 ng/mL (range, 1.3–8.0 ng/mL). The within-subject variation was 3.7 % (95 % confidence interval (CI) 3.0–4.4 %), the between-subject variation was 31.5 % (95 % CI 23.1–39.8 %), and the analytical variation was 3.4 % (95 % CI 2.9–4.1 %). The reference change value was 13.3 % for an increase in tryptase at a 95 % level of significance. No significant day-to-day variation was observed (p=0.77), while a minute decrease in the serum concentration was observed during the day (p<0.0001).

Conclusions
Serum tryptase is a tightly regulated biomarker with very low within-subject variation, no significant day-to-day variation, and only minor semidiurnal variation. In contrast, a considerable between-subject variation exists. This establishes serum tryptase as a well-suited biomarker for monitoring.
Influence of nano chromium addition on the corrosion and erosion–corrosion behavior of cupronickel 70/30 alloy in seawater
Authors: Nattah Ayad Mohammed , Salim Asia Mishaal , Dawood Nawal Mohammed 
Published: October 2023

Abstract
Cupronickel alloys have found widespread use in various applications such as heat exchangers, refrigeration systems, equipment, pumps, and pipes. However, the inherent structure of cupronickel alone may not be able to withstand certain aggressive environments effectively. To address this issue, the mechanical properties and corrosion resistance of cupronickel alloys can be enhanced by carefully selecting the appropriate alloying compositions. The addition of nano chromium (20 nm) has been proposed as a means of designing cupronickel alloys with improved performance. In the present study, corrosion and erosion–corrosion behaviors of cupronickel 70/30 alloys produced by the casting method without and with three different additions of nano Cr (1, 1.2, and 1.5 wt%) were investigated. The prepared specimens were subjected to electrochemical tests in 3.5 wt% sodium chloride solutions to evaluate their corrosion behavior. Additionally, an erosion–corrosion test was conducted at an impact angle of 90°, using a slurry solution containing 1 wt% SiO2 sand in 3.5 wt% NaCl solution as the erodent. The specimens were comprehensively characterized using scanning electron microscopy, energy-dispersive X-ray spectroscopy, and X-ray diffraction techniques. The surfaces of the alloy specimens exhibited superficial attacks, but no pits were observed. Moreover, the surfaces developed a greenish coloration. The electrochemical tests conducted using saline solution revealed that the corrosivity of the cupronickel alloy with nano chromium addition varied from moderate to low, depending on the selected concentration. Despite undergoing corrosion in the saline environment, the modified cupronickel alloys demonstrated good resistance to this corrosive process. Therefore, they can be considered suitable for use in highly aggressive environments, such as in seawater capture systems. The erosion–corrosion test results indicated that the addition of nano chromium significantly enhanced the resistance of the specimens to erosion–corrosion. At 1.5 wt% Cr, the erosion–corrosion rate was reduced by 99.27%.
On the regularity theory for mixed anisotropic and nonlocal p-Laplace equations and its applications to singular problems
Authors: Garain Prashanta , Kim Wontae , Kinnunen Juha 
Published: October 2023

Abstract
We establish existence results for a class of mixed anisotropic and nonlocal p-Laplace equations with singular nonlinearities. We consider both constant and variable singular exponents. Our argument is based on an approximation method. To this end, we also discuss the necessary regularity properties of weak solutions of the associated non-singular problems. More precisely, we obtain local boundedness of subsolutions, the Harnack inequality for solutions and the weak Harnack inequality for supersolutions.
Effect of refining slag compositions on its melting property and desulphurization
Authors: Li Shisen , Kong Lingzhong , Xu Zhaolong 
Published: October 2023

Abstract
To investigate the feasibility of the refining slag with low fluoride, some oxides such as Al2O3, SiO2, B2O3, and Li2O were used to replace CaF2 in refining slag with the equivalent weight replacement method, and then the melting temperature and desulphurization capacity of slag were determined. The results show that the melting temperature of slag (CaF2 < 4 mass% and Al2O3 > 28 mass%) is less than 1,706 K, when CaF2 is substituted by Al2O3. This slag is able to decrease [S] in steel to less than 0.0060 mass%. In the case of substitution of CaF2 by SiO2, the melting temperature increases, while the desulphurization rate decreases. The fluxing action of B2O3 is stronger than that of CaF2, and the melting temperature decreases to 1,561 K when CaF2 is substituted by B2O3. Li2O can not only lower the melting temperature of slag but also improve the desulphurization rate.
On ℐ2(𝒮θ
p,r

)-summability
of double sequences in neutrosophic normed spaces
Authors: Kumar Vijay , Ganaie Inayat Rasool , Sharma Archana 
Published: October 2023

Abstract
In this article, we aim to define

ℐ
2

⁢

(
𝒮
)

{\mathcal{I}_{2}(\mathcal{S})}

-summability
and

ℐ
2

⁢

(

𝒮

θ

p
,
r

)

{\mathcal{I}_{2}(\mathcal{S}_{{\theta}_{p,r}})}

-summability,
and obtain interesting relationships among these by imposing certain conditions on p and r. Finally, we show that the space

ℐ
2

⁢

(

𝒮

θ

p
,
r

⁢

(
G
,
B
,
Y
)

)

∩

l
∞
2

⁢

(
V
)

\mathcal{I}_{2}(\mathcal{S}_{{\theta}_{p,r}}(G,B,Y))\cap l^{2}_{\infty}(V)

is a closed subspace of

l
∞
2

⁢

(
V
)

{l^{2}_{\infty}(V)}

.
Nondensely defined partial neutral functional integrodifferential equations with infinite delay under the light of integrated resolvent operators
Authors: El Matloub Jaouad , Ezzinbi Khalil 
Published: October 2023

Abstract
In this work, we mainly focus on the local existence and regularity of integral solutions for a class of nondensely defined partial neutral functional integrodifferential equations with unbounded delay. We use the theory of integrated resolvent operators introduced by Oka
[H. Oka,
Integrated resolvent operators,
J. Integral Equations Appl. 7 1995, 2, 193–232].
Finally, we provide an example to demonstrate the basic findings of our work.
Never Say Never: Reproduction of Intergenerational Will and Return of Ideal—Interview with Wang Baoqiang
Authors: Yao Wu , Yirui Cheng 
Published: October 2023

Abstract
Wang Baoqiang is the director of Never Say Never (2023), as well as being a well-known actor. His acting roles include Blind Shaft (Mang jing, 2003), A World Without Thieves (Tianxia wuzei, 2004) and Detective Chinatown series (Tangrenjie tan’an). Following Buddies in India (Danao tianzhu, 2017), Never Say Never is, Wang Baoqiang’s second directorial work: taking six years to hone, the film is a realistic depiction of the story of Xiang Tenghui, a former boxing champion, who is determined to train orphans from China’s remote countryside. Through sports competitions, he aims to provide them with the chance for a better life. This interview is based on the actors’ performances, the director’s audiovisual expression and the pursuit of values; it discusses the film’s reproduction of intergenerational will and the protagonist’s ideal for returning to the middle-aged stage of life, offering an in-depth portrait of the multi-dimensional thinking and artistic insights of Wang Baoqiang, as an experienced actor exploring the path of film directing.
The N221D variant in PCSK1 is highly prevalent in childhood obesity and can influence the metabolic profile
Authors: Guijo Blanca , Argente Jesús , Martos-Moreno Gabriel Ángel 
Published: October 2023

Abstract

Objectives
To study the prevalence and influence on metabolic profile of the prohormone-convertase-1 (PCSK1) N221D variant in childhood obesity, proven its role in the leptin-melanocortin signaling pathway as in proinsulin and other prohormone cleavage.

Methods
Transversal study of 1066 children with obesity (mean age and BMI Z-score 10.38 ± 3.44 years and +4.38 ± 1.77, respectively), 51.4 % males, 54.4 % prepubertal, 71.5 % Caucasians and 20.8 % Latinos. Anthropometric and metabolic features were compared between patients carrying the N221D variant in PCSK1 and patients with no variants found after next generation sequencing analysis of 17 genes (CREBBP, CPE, HTR2C, KSR2, LEP, LEPR,
MAGEL2, MC3R, MC4R, MRAP2, NCOA1, PCSK1, POMC, SH2B1,
SIM1, TBX3 and TUB) involved in the leptin-melanocortin pathway.

Results
No variants were found in 531 patients (49.8 %), while 68 patients carried the PCSK1 N221D variant (42 isolately, and 26 with at least one additional gene variant). Its prevalence was higher in Caucasians vs. Latinos (χ2 7.81; p<0.01). Patients carrying exclusively the PCSK1 N221D variant (n=42) showed lower insulinemia (p<0.05), HOMA index (p<0.05) and area under the curve for insulin in the oral glucose tolerance test (p<0.001) and higher WBISI (p<0.05) than patients with no variants, despite similar obesity severity, age, sex and ethnic distribution.

Conclusions
The N221D variant in PCSK1 is highly prevalent in childhood obesity, influenced by ethnicity. Indirect estimation of insulin resistance, based on insulinemia could be byassed in these patients and underestimate their type 2 diabetes mellitus risk.
Artificial Turf Increases the Physical Demand of Soccer by Heightening Match Running Performance Compared with Natural Grass
Authors: Modric Toni , Esco Michael , Perkovic Sandro , Basic Zlatko , Versic Sime , Morgans Ryland , Sekulic Damir 
Published: October 2023

AbstractModric, T, Esco, M, Perkovic, S, Basic, Z, Versic, S, Morgans, R, and Sekulic, D. Artificial turf increases the physical demand of soccer by heightening match running performance compared with natural grass.J Strength Cond Res37(11): 2222–2228, 2023—This study aimed to determine differences in match running performance (MRP) of elite soccer players (n= 31) during matches played on artificial turf (AT) and natural grass (NG). The players' MRP (AT; 131 observations, NG; 135 observations) were collected during official matches (n= 32) using global positioning system and classified according to their playing positions as central defenders, central midfielders, fullbacks, forwards, and wingers. The MRP variables included total distance covered (TD), low-intensity running (LIR), moderate-intensity running (MIR), high-intensity running (HIR), total (Tacc) and high-intensity accelerations (Hacc), and total (Tdec) and high-intensity decelerations (Hdec). The influence of match outcome, location, and opponent quality was controlled for as contextual factors. Playing matches on AT resulted in (a) increased TD (Cohen'sd(d) = 0.55, 0.61, and 0.28, respectively), MIR (d= 0.91, 0.79, and 0.49, respectively), and HIR (d= 0.67, 0.44, and 0.38, respectively) for central defenders, central midfielders, fullbacks; (b) increased Tacc (d= 0.38, 0.37, and 0.4, respectively) and Tdec (d= 0.31, 0.34, and 0.31, respectively) for central defenders, central midfielders, and wingers; and (c) decreased Hdec (d= −1.5) for forwards. These results show that playing on AT is more physically demanding for defensive and midfield players than playing on NG. Soccer coaches should consider implementing preparatory strategies that mitigate the increased demands of playing on AT for these players, especially before a competitive period when transitions between pitch surfaces routinely occur.
Validity and Reliability of Thoracic-Mounted Inertial Measurement Units to Derive Gait Characteristics During Running
Authors: Horsley Benjamin J. , Tofari Paul J. , Halson Shona L. , Kemp Justin G. , Chalkley Daniel , Cole Michael H. , Johnston Rich D. , Cormack Stuart J. 
Published: October 2023

Abstract
Horsley, BJ, Tofari, PJ, Halson, SL, Kemp, JG, Chalkley, D, Cole, MH, Johnston, RD, and Cormack, SJ. Validity and reliability of thoracic-mounted inertial measurement units to derive gait characteristics during running. J Strength Cond Res 38(2): 274–282, 2024—Inertial measurement units (IMUs) attached to the tibia or lumbar spine can be used to analyze running gait but, with team-sports, are often contained in global navigation satellite system (GNSS) units worn on the thoracic spine. We assessed the validity and reliability of thoracic-mounted IMUs to derive gait characteristics, including peak vertical ground reaction force (vGRFpeak) and vertical stiffness (Kvert). Sixteen recreationally active subjects performed 40 m run throughs at 3–4, 5–6, and 7–8 m·s−1. Inertial measurement units were attached to the tibia, lumbar, and thoracic spine, whereas 2 GNSS units were also worn on the thoracic spine. Initial contact (IC) from a validated algorithm was evaluated with F1 score and agreement (mean difference ± SD) of gait data with the tibia and lumbar spine using nonparametric limits of agreement (LoA). Test-retest error {coefficient of variation, CV (95% confidence interval [CI])} established reliability. Thoracic IMUs detected a nearly perfect proportion (F1 ≥ 0.95) of IC events compared with tibia and lumbar sites. Step length had the strongest agreement (0 ± 0.04 m) at 3–4 m·s−1, whereas contact time improved from 3 to 4 (−0.028 ± 0.018 second) to 7–8 m·s−1 (−0.004 ± 0.013 second). All values for Kvert fell within the LoA at 7–8 m·s−1. Test-retest error was ≤12.8% for all gait characteristics obtained from GNSS units, where Kvert was most reliable at 3–4 m·s−1 (6.8% [5.2, 9.6]) and vGRFpeak at 7–8 m·s−1 (3.7% [2.5, 5.2]). The thoracic-spine site is suitable to derive gait characteristics, including Kvert, from IMUs within GNSS units, eliminating the need for additional sensors to analyze running gait.
Loss of Depalmitoylation Disrupts Homeostatic Plasticity of AMPARs in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis
Authors: Koster Kevin P. , Flores-Barrera Eden , Artur de la Villarmois Emilce , Caballero Adriana , Tseng Kuei Y. , Yoshii Akira 
Published: October 2023

Protein palmitoylation is the only reversible post-translational lipid modification. Palmitoylation is held in delicate balance by depalmitoylation to precisely regulate protein turnover. While over 20 palmitoylation enzymes are known, depalmitoylation is conducted by fewer enzymes. Of particular interest is the lack of the depalmitoylating enzyme palmitoyl-protein thioesterase 1 (PPT1) that causes the devastating pediatric neurodegenerative condition infantile neuronal ceroid lipofuscinosis (CLN1). While most of the research on Ppt1 function has centered on its role in the lysosome, recent findings demonstrated that many Ppt1 substrates are synaptic proteins, including the AMPA receptor (AMPAR) subunit GluA1. Still, the impact of Ppt1-mediated depalmitoylation on synaptic transmission and plasticity remains elusive. Thus, the goal of the present study was to use thePpt1−/−mouse model (both sexes) to determine whether Ppt1 regulates AMPAR-mediated synaptic transmission and plasticity, which are crucial for the maintenance of homeostatic adaptations in cortical circuits. Here, we found that basal excitatory transmission in thePpt1−/−visual cortex is developmentally regulated and that chemogenetic silencing of thePpt1−/−visual cortex excessively enhanced the synaptic expression of GluA1. Furthermore, triggering homeostatic plasticity inPpt1−/−primary neurons caused an exaggerated incorporation of GluA1-containing, calcium-permeable AMPARs, which correlated with increased GluA1 palmitoylation. Finally, Ca2+imaging in awakePpt1−/−mice showed visual cortical neurons favor a state of synchronous firing. Collectively, our results elucidate a crucial role for Ppt1 in AMPAR trafficking and show that impeded proteostasis of palmitoylated synaptic proteins drives maladaptive homeostatic plasticity and abnormal recruitment of cortical activity in CLN1.SIGNIFICANCE STATEMENTNeuronal communication is orchestrated by the movement of receptors to and from the synaptic membrane. Protein palmitoylation is the only reversible post-translational lipid modification, a process that must be balanced precisely by depalmitoylation. The significance of depalmitoylation is evidenced by the discovery that mutation of the depalmitoylating enzyme palmitoyl-protein thioesterase 1 (Ppt1) causes severe pediatric neurodegeneration. In this study, we found that the equilibrium provided by Ppt1-mediated depalmitoylation is critical for AMPA receptor (AMPAR)-mediated plasticity and associated homeostatic adaptations of synaptic transmission in cortical circuits. This finding complements the recent explosion of palmitoylation research by emphasizing the necessity of balanced depalmitoylation.