bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term Impact of Telehealth (Diabetes Tele Management System®) Intervention on Treatment Satisfaction, Quality of Life, and Clinical Outcomes in People with Type 2 Diabetes: A 15-year Retrospective Cohort Study
Authors: Jothydev Krishnadev , Basanth Anjana , Chandran Gopika Beena , Shankar Arun , Krishnan Gopika , Sanal Geethu , Lally Jayasree , Sreelakshmi R. , Jothydev Sunitha , Kesavadev Jothydev 
Published: December 2023

Abstract

Background:
Telehealth interventions have gained prominence as a promising strategy for improving medication adherence and patient outcomes among individuals with chronic illnesses. This study investigates the Diabetes Tele Management System (DTMS®), a comprehensive telemedicine-based program operating in Kerala, India, since 1997, to assess its impact on treatment satisfaction, quality of life (QoL), and clinical outcomes in individuals with type 2 diabetes (T2D).

Methodology:
A retrospective cohort design was employed, analyzing data from electronic medical records over a 15-year period. Participants were categorized into a treatment group (TG) enrolled in DTMS® and a control group (CG) receiving conventional care. Propensity score matching minimized confounding factors. Clinical parameters, diabetes-related complications, and treatment satisfaction were assessed. QoL was evaluated using the EuroQol five dimensions (EQ-5D) questionnaire.

Results:
Among 451 participants, the TG (n = 267) experienced significantly lower rates of micro-macrovascular complications compared to the CG (n = 184) (P < 0.0001). TG participants showed improvements in glycated hemoglobin, fasting blood glucose, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, diastolic blood pressure, total cholesterol, and weight (P < 0.05). QoL was notably better in the TG across all EQ-5D domains (P < 0.001). Treatment satisfaction was also higher in the TG (P < 0.001).

Conclusion:
The DTMS® telemedicine program demonstrated substantial benefits in terms of reduced complications, improved clinical parameters, enhanced QoL, and increased treatment satisfaction among people with T2D. This study underscores the potential of telehealth interventions, like DTMS®, in diabetes management, particularly in improving long-term outcomes and patient well-being.
Continuous Glucose Monitoring in Non-Insulin Type 2 Diabetes
Authors: Kesavadev Jothydev , Saboo Banshi , Makkar Brij Mohan , Agarwal Sanjay , Chawla Manoj , Chandran Vysakh , Shankar Arun , Basanth Anjana 
Published: December 2023

Abstract
Diabetes mellitus, a global health concern, is characterized by complex pathophysiology and presents diverse clinical challenges. Effective management of diabetes hinges on key principles such as glycemic control, lifestyle modifications, and adherence. In non-insulin-requiring Type 2 diabetes (T2D), persistent elevated HbA1c levels remain a challenge. Continuous glucose monitoring (CGM) is pivotal, serving as a cornerstone for optimizing therapy, mitigating hypoglycemia, and reducing the financial burden. Unlike traditional self-monitoring of blood glucose (SMBG), CGM offers continuous, pain-free data, aiding treatment decisions. This review explores CGM’s multifaceted role in non-insulin requiring T2D, scrutinizing HbA1c reduction, glycemic variability, time in range (TIR), exercise, dietary management, early comorbidity detection, and cost-effectiveness. CGM empowers users to monitor and manage their glycemic levels, making it an effective tool for HbA1c reduction. Glycemic variability poses risks, and CGM provides valuable metrics like time below range (TBR), time in range (TIR), and time above range (TAR). CGM effectively minimizes glycemic variability and improves TIR in non-insulin requiring T2D. Additionally, CGM aids in real-time decision-making for physical activity and dietary choices, enhancing the effectiveness of lifestyle modifications. It also assists healthcare providers in identifying early signs of comorbidities, particularly cardiovascular disease, and diabetic retinopathy, through monitoring glycemic variability. While CGM devices may incur costs, studies suggest their cost-effectiveness, considering long-term benefits and complications prevention. This review underscores CGM’s importance in T2D management, even for non-insulin-requiring individuals. Recommendations include CGM use for newly diagnosed people with T2D, those with uncontrolled diabetes, and those adjusting treatments. Personalized glycemic control goals are proposed, aligning CGM’s role in managing hypoglycemia, hyperglycemia, and glycemic variability in T2D. As CGM technology advances and becomes more accessible, it is poised to play an increasingly pivotal role in diabetes management. Crucially, CGM should be employed in consultation with healthcare providers, considering regional disparities in cost-effectiveness and accessibility influenced by insurance coverage and government interventions.
Haplotype Diversity of Mitochondrial DNA in the Jat Population of Haryana
Authors: Sharma Sapna , Verma Kapil 
Published: December 2023

Abstract

Background:
The genetic representation of various population groups has been successfully attempted by studying hypervariable regions of human mitochondrial DNA (mtDNA) for forensic purposes. In this view of the fact, there are very few studies in the northern region of India focusing on mtDNA variations. The usage of mtDNA typing for forensic purposes has however been delayed in most states, especially Haryana, due to lack of mtDNA pool database for Haryana populations.

Aims and Objectives:
Since, there has been no elaborated mtDNA study on Jat population of Haryana, thus, the genetic variability of Jat population of Haryana was estimated by examining the hypervariable regions (HVI, HVII, and HVIII) of mtDNA.

Materials and Methods:
Blood samples of maternally unrelated individuals have been collected.

Statistical Analysis Used:
Different parameters and molecular diversity indices were computed.

Results:
The polymorphism has been observed with their corresponding haplogroups. The phylogenetic relationship was inferred between different haplogroups.

Conclusion:
A high level of variation and a low random match probability was observed in all the three hypervariable regions of mtDNA, indicating its utility for forensic purposes.
Effect of nonsurgical periodontal therapy on interleukin-35 level in gingival crevicular fluid
Authors: Jadhav Ashwini , Rathod Surekha Ramrao , Kolte Abhay P. , Kasliwal Palak 
Published: December 2023

ABSTRACT

Background:
Clinical attachment level (CAL), alveolar bone loss, and periodontal pockets constitute the major signs of periodontitis. The interaction between the host and the bacteria that forms a biofilm on the tooth surface is one of the major etiologies of periodontal disorders.

Aim:
The aim of this study was to assess interleukin-35 (IL-35) levels pre and post nonsurgical periodontal therapy (NSPT) in healthy individuals and gingivitis and periodontitis patients.

Materials and Methods:
IL-35 level in gingival crevicular fluid (GCF) and clinical parameters were assessed in 60 individuals. Biochemical analysis was done by enzyme-linked immunosorbent assay. Individuals in Group I were in good health; those in Groups II and III had gingivitis and periodontitis, respectively. Study individuals were evaluated at baseline and 3 months after NSPT.

Results:
Group III differed from Group II in that it had higher CAL (7.60), plaque index (2.8929), and periodontal probing depth (5.8500 mm) values, as well as lower papillary bleeding index (2.1170) and gingival index (2.1085) values. The concentrations of IL-35 in GCF varied among the groups, with Group III having the lowest concentrations and rising gradually to Groups II and I. In addition, from baseline to 3 months, the IL-35 levels in GCF significantly decreased in both Groups II and III. The results show that Groups II and III have lower GCF levels of IL-35 than Group I, suggesting that IL-35 is a major factor in the development of periodontal diseases.

Conclusion:
Group I had considerably greater GCF IL-35 values than Group II and III both before and after NSPT.
İZMİR İLİ NÜFUSUNUN GELİŞİMİ VE DEĞİŞİMİNE DAİR DEMOGRAFİK ANALİZ ÇALIŞMASI
Authors: AYHAN Fatih , YAZICI Hakkı 
Published: December 2023

Türkiye’nin tarım, sanayi, ticaret, turizm, ulaşım, eğitim, sağlık, finans vb. faaliyetler bakımından gelişmiş illerinden biri olan İzmir, sahip olduğu sosyoekonomik özelliklere bağlı olarak her dönem yoğun nüfusu barındırmıştır. Cumhuriyet’in ilk nüfus sayımının yapıldığı 1927 yılında 526.005 olan İzmir’in nüfusu 1950 yılından sonra sanayiye bağlı olarak göç hareketlerinin etkisiyle 1960 yılında bir milyonu aşarken 2022 yılı itibariyla 4.462.056’a ulaşmıştır.
Bu çalışmada İzmir ili nüfusunun 1927 yılından günümüze kadar geçirdiği değişim ve dönüşüm nüfus coğrafyası kapsamında incelenmiştir. Bu amaçla İzmir’e ait nüfusun tarihi gelişimi, dönemler itibariyla artış hızı, kır-kent nüfus oranı, cinsiyet ve yaş yapısı, göç hareketleri vb. demografik unsurlara yer verilmiştir. Yapılan çalışma ulusal ve bölgesel çapta öneme sahip olan İzmir ilinin yaklaşık yüz yıllık dönemde yaşadığı demografik gelişim ve dönüşümün boyutu hakkında fikir verir niteliktedir.
Os cuidados ético e moral sobre o cinema e a televisão no Brasil
Authors: Melo Ana Cláudia da Cruz , Silva Carmen Lucia Souza da 
Published: December 2023

Neste artigo, apreende-se reflexão sobre como os conceitos de ética e moral ao longo de décadas, no Brasil, foram utilizados em nome de uma pretensa qualidade no Cinema e na Televisão, durante o regime militar, de 1964 a 1985, e pós-redemocratização, quando sucessivas portarias de classificação prévia/indicativa foram emitidas pelo Ministério da Justiça, após o fim da Censura Federal. São fontes de análise deste artigo, matérias de jornais, além dos Relatórios Anuais da Divisão de Censura de Diversões Públicas (DCDP), de 1972 a 1987, entre outros documentos, do período da ditadura militar, sob a guarda do Arquivo Nacional. Embasam as reflexões a teoria dos afetos de Spinoza e os escritos de Deleuze
Existence of original drug molecules in ultra high dilutions
Authors: Chattopadhyay Dr Sanjib 
Published: December 2023

Abstract:

Background: Some workers postulated that homeopathic medicines have got some alterations of hydrogen bonded network in water molecules for their activity, but according to others the original drug molecule remains present as nanoparticles. Objective: To prove experimentally whether traces of medicine molecules are present in ultra high dilution and determine its apparent cause. Materials and Methods: To detect existence of Copper ion in 5 ultra high dilutions (6c, 30c, 200c, 1000c and 10000c) in Cuprum metallicum were subjected to Atomic Absorption Spectrophotometry. An experiment was also set up to determine how one can obtain trails of original molecules in highly diluted solutions beyond Avogadro’s limit where a solution of copper sulfate was successively diluted decimally in three different ways: NSW (Non-”Succussed” Water), SW(“Succussed” Water), SWE (“Succussed” Water with 50% ethanol) and was studied by UV-Vis Spectrophotometer. Result: Existence of a Copper ion was found asymptotically decreasing through all the five dilutions. In the second experiment it was observed that in case of NSW solution the Optical Density (OD) reaches to non-detectable (ND) range earlier, but for SW and SWE later. Conclusion: Some sorts of non-homogeneity established in “succussed” alcoholic dilutions due to fall of dielectric constant. With the increase of dilution more proportion of solute molecules in the form of nanoparticles covered by solvent layers become transferred to the next serial dilution. Drugs, tightly packed by ethanol (‘nanoparticles’) easily enter inside cell, bring symptoms to the “provers” and cure patients as well when applied in minute dose.
Indigenous Festival dan Pembelajaran Gastronomi pada Program Studi Perhotelan
Authors: Abdillah Fitri Abdillah , Ayuningsih Sri Fajar , Rachmat Timotius Agus 
Published: December 2023

Latar Belakang: festival bagi masyarakat Osing di Banyuwangi merupakan aktivitas ritual yang wajib dilaksanakan sebagai penolak bala, bersyukur ke hadirat Tuhan YME, serta pengharapan tentang masa depan yang baik. Dalam berbagai ritual festival yang ada selalu melibatkan gastronomi sebagai perangkat utamanya.
Tujuan: penelitian ini bertujuan untuk menemukenali mengembangkan pembelajaran gastronomi Indonesia melalui berbagai jenis hidangan ritual yang terlibat dalam gelaran festival Tumpeng Sewu dan Barong Ider Bumi masyarakat Osing di Banyuwangi
Metode: metode penelitian yang digunakan adalah mix method dengan pembobot lebih pada metode kualitatif yang dipadukan dengan literature study
Hasil dan Pembahasan: temuan penelitian menunjukkan bahwa kegiatan festival pada masyarakat Osing dapat diteladani dalam pembelajaran gastronomi pada prodi perhotelan dengan (1) memasukkan bahasan tentang gastronomi Indonesia sebagai mata kuliah utama; (2) masyarakat Osing Kemiren memiliki keramah-tamahan yang genuine dan dapat diadopsi sebagai keramah-tamahan ala Indonesia dalam pembelajaran Service; (3) Tour gastronomi dapat diciptakan sebagai atraksi berupa penyediaan bahan baku alami lokal, pemasakan, penyajian, dan tata cara makan versi Osing; (4) dengan mengadopsi siklus manajemen pengetahuan berbagai hidangan ritual dapat dieksplisitkan dengan menyusun berbagai buku tentang hidangan Osing.
Saran: kepedulian perguruan tinggi dalam mewujudkan pengetahuan eksplisit dari kearifan lokal masyarakat akan berkontribusi terhadap keberlanjutan masyarakat adat Osing.
PEMBANGUNAN KEAHLIAN PUBLIC SPEAKING MELALUI KEGITAN KHITOBAH DI PONDOK PESANTREN ASAASUNNAJAAH KESUGIHAN CILACAP
Authors: Yusri Wahidah  , M. Fatikhun  
Published: December 2023

This study aims to determine the public speaking skills development program for students through khitobah activities and to find out the results of khitobah activities on the development of students' public speaking skills. The method used in this research is a qualitative descriptive approach that explains, describes systematically based on the phenomena that occur. Data collection techniques used are observation, interviews, and documentation. Meanwhile, to analyze the researchers used data reduction, data presentation, and drawing conclusions.
The results of this study indicate that the program for developing public speaking skills for students is through khitobah activities, namely: first, being the host or MC at the khitobah activity. Second, to be a welcoming speech at the sermon activity. Third, being a speaker at a sermon activity. By frequently participating in sermon activities for students and always practicing and continuing to practice when they become officers at sermon activities, students' public speaking skills can be built. While the results of the sermon activity on the development of students' public speaking skills are: first, students become more confident. Second, the students have the courage to appear in public. Third, be mentally strong. Fourth, mature yourself. Fifth, useful for the future of students.
Hubungan Antara Faktor Genetik dan Lingkungan Perkembangan Autisme dan Attention Deficit Hyperactivity Disorder (ADHD)
Authors: Ginting Rafael Lisinus , Sagala Anisah Khairiyyah , Nst Maharani Arfah , Simamora Maulana Stifani , Pulungan Rizky Aprilia , Silalahi Rostika Uli , Ginting Sagita Natalina Br , Pane Sarah Asti Adinda , Fatimah Yasmine Noor 
Published: December 2023

Autisme dan Attention Deficit Hyperactivity Disorder (ADHD) adalah dua gangguan perkembangan saraf yang sering terjadi pada anak-anak. Penelitian telah menunjukkan bahwa kedua gangguan tersebut dipengaruhi oleh faktor genetik dan lingkungan. Faktor genetik berperan dalam perkembangan autisme dan ADHD melalui berbagai mekanisme, termasuk mutasi gen, perubahan epigenetik, dan interaksi gen-lingkungan. Mutasi gen dapat menyebabkan perubahan pada protein yang terlibat dalam perkembangan otak. Perubahan epigenetik dapat mempengaruhi bagaimana gen diekspresikan. Interaksi gen-lingkungan dapat terjadi ketika faktor genetik membuat seseorang lebih rentan terhadap pengaruh lingkungan tertentu. Faktor lingkungan yang dapat memengaruhi perkembangan autisme dan ADHD meliputi: Infeksi prenatal, seperti rubella, cytomegalovirus, dan toksoplasma, paparan zat beracun selama kehamilan, seperti pestisida dan logam berat, paparan stres selama kehamilan, paparan zat beracun selama masa kanak-kanak, seperti timbal dan asap rokok, Cedera kepala, Trauma psikologis. Metode yang digunakan dalam penelitian ini adalah kualitatif dengan menggunakan kajian literatur sebagai instrumen. Penelitian lebih lanjut diperlukan untuk memahami lebih lanjut hubungan antara faktor genetik dan lingkungan dalam perkembangan autisme dan ADHD. Penelitian ini dapat membantu untuk mengembangkan strategi pencegahan dan intervensi yang lebih efektif.
PENGARUH MOTIVASI KELUARGA DAN EFIKASI DIRI TERHADAP MINAT MENJADI GURU EKONOMI PADA SISWA DI SMA NEGERI 2 TONDANO
Authors: Grace Vinta , Tawas Yance , Makaliwe Niny 
Published: December 2023

Abstrak.
Penelitian ini berusaha menjawab pertanyaan, "Bagaimana tingkat self-efficacy siswa, serta jumlah dukungan yang mereka dapatkan dari keluarga mereka, mempengaruhi keputusan mereka untuk mengejar karir sebagai guru ekonomi?" Sebuah survei digunakan sebagai metodologi untuk penyelidikan ini. Kecamatan Tondano Selatan Kabupaten Minahasa menjadi lokasi pelaksanaan penelitian. Sampel penelitian ini berasal dari SMA Negeri 2 Tondano, dan terdiri dari tiga puluh murid. Untuk mengumpulkan informasi, kuesioner dikirim ke responden. Analisis regresi linier berganda adalah apa yang digunakan saat melihat data. Menurut hasil, baik motivasi keluarga dan self-efficacy berdampak pada minat dalam mengajar ekonomi, dan kedua sifat mempengaruhi minat mengajar dengan cara yang saling melengkapi. Selain itu, efikasi diri dan motivasi keluarga keduanya mempengaruhi minat mengajar secara umum.
Kata kunci: Motivasi Keluarga, Efeksi diri, minat menjadi guru

Abstract
This research seeks to answer the question, "How does a student's level of self-efficacy, as well as the amount of support they get from their family, affect their decision to pursue a career as an economics teacher?" A survey was employed as the methodology for this investigation. The South Tondano sub-district of the Minahasa Regency was the location where the study was carried out. The sample for this research came from SMA Negeri 2 Tondano, and it consisted of thirty pupils. In order to gather information, questionnaires are sent out to respondents. Multiple linear regression analysis is what is used while looking at the data. According to the results, both family motivation and self-efficacy impacted interest in teaching economics, and both traits affected interest in teaching in a complementary way. Furthermore, self-efficacy and family motivation both affected interest in teaching in general.
Keywords: Family Motivation, Self-Effec, Interest in Becoming a Teacher
PENGARUH MEDIA PEMBELAJARAN DAN MOTIVASI BELAJAR TERHADAP HASIL BELAJAR AKUNTANSI SISWA KELAS X DI SMK NEGERI 1 RATAHAN
Authors: Kolinug Evriani Juniati , Makaliwe Niny , Oroh Silvana 
Published: December 2023

AbstrakPenelitian ini bertujuan untuk mengetahui bagaimana pengaruh media pembelajaran dan motivasi belajar terhadap hasil belajar akuntansi siswa kelas X jurusan akuntansi di SMK Negeri 1 Ratahan, metode yang digunakan dalam penelitian ini adalah metode kuantitatif dengan sampel berjumlah 20 siswa. Metode pengumpulan data menggunakan angket dan dokumentasi, setelah data terkumpul dilanjutkan dengan analisis regresi linear berganda, analisis korelasi sederhana dan analisis korelasi ganda dengan menggunakan SPSS 29. Adapun hasil penelitian ini menunjukkan: (1) terdapat pengaruh yang signifikan antara media pembelajaran terhadap hasil belajar akuntansi siswa kelas X di SMK Negeri 1 Ratahan; (2) terdapat pengaruh yang signifikan antara motivasi belajar terhadap hasil belajar akuntansi siswa kelas X di SMK Negeri 1 Ratahan (3) terdapat pengaruh yang signifikan antara media pembelajaran dan motivasi belajar terhadap hasil belajar akuntansi siswa kelas X di SMK Negeri 1 Ratahan.Kata Kunci: Media Pembelajaran, Motivasi Belajar, Hasil Belajar
AbstractThis research aims to find out how learning media and learning motivation influence the accounting learning outcomes of class X students majoring in accounting at SMK Negeri 1 Ratahan. The method used in this research is a quantitative method with a sample of 20 students. The data collection method uses questionnaires and documentation, after the data is collected it is continued with multiple linear regression analysis, simple correlation analysis and multiple correlation analysis using SPSS 29. The results of this research show: (1) there is a significant influence between learning media on accounting learning outcomes class X students at SMK Negeri 1 Ratahan; (2) there is a significant influence between learning motivation on the accounting learning outcomes of class X students at SMK Negeri 1 Ratahan (3) there is a significant influence between learning media and learning motivation on the accounting learning outcomes of class.Keywords: Learning Media, Learning Motivation, Learning Outcomes
PENGARUH KOMPETENSI PROFESIONAL DAN MOTIVASI BELAJAR TERHADAP KEMAMPUAN BELAJAR SISWA KELAS XI DI SEKOLAH SMK NEGERI 1 AMURANG
Authors: Pattyranie Meisy Magdalena , Siswanto Sri P. , Ranti Devyano V.F 
Published: December 2023

Penelitian Ini Bertujuan Untuk Mengetahui PengaruhKompetensi Profesional Dan Motivasi Belajar SiswaTerhadap Kompetensi Guru merupakan salasatu factor keberhasilan pembelajaran disekolah, permasalahan yang dijumpai terdaat beberapa Siswa yang masih belum maksimal termotifasi dalam pembelajaran dikelas. Kemampuan Belajar Siswa Kelas XI SMK Negeri 1 Amurang. Populasi Dalam Penelitian Ini Adalah Siswa Kelas XI SMK Negeri 1 AmurangYang Berjumlah 56 Siswa. Sedangkan Sampel Dalam Penelitian Ini Adalah 49 . Berdasarkan hasil koefisien korelasidiatas sebesar 0,220. Dalam menentukan koefisiendeterminan dilakukan untuk menentukan besar kontribusiKompetensi Profesional dan Motivasi Belajar Siswa terhadap Kemampuan belajar siswa dengan menggunakan rumus KD = r2 x 100% = 0,220 x 100% = 22,0 % dengan demikian besar kontribusi Kompetensi Profesional dan Motivasi Belajar Siswaterhadap Kemampuan belajar siswa adalah 22,0%. Berdasarkan hasil uji diatas, dapat dilihat f hitung sebesar 6,701 > f tabel sebesar 3,200 dengan demikian KompetensiProfesional dan Motivasi Belajar Siswa terhadap Kemampuanbelajar siswa secara simultan berpengaruh terhadap Kemampuan belajar siswa sebesar 22,0 %.
This research aims to determine the influence of professional competency and student learning motivation on teacher competency, which is one of the factors for the success of learning at school. The problem encountered is that some students are still not maximally motivated in learning in class. Learning Ability of Class XI Students at SMK Negeri 1 Amurang. The population in this study was Class XI students at SMK Negeri 1 Amurang, totaling 56 students. Meanwhile, the sample in this study was 49. Based on the results of the correlation coefficient above, it is 0.220. In determining the determinant coefficient, it is carried out to determine the contribution of Professional Competency and Student Learning Motivation to student learning abilities using the formula KD = r2 x 100% = 0.220 x 100% = 22.0%, thus the contribution of Professional Competency and Student Learning Motivation to Ability is large. student learning is 22.0%. Based on the test results above, it can be seen that fcount is 6.701 > f table is 3.200, thus Professional Competence and Student Learning Motivation on students' learning abilities simultaneously influence students' learning abilities by 22.0%.