bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence, Surgical, and Medical Management of Patients with Endometriosis amongst Indian Women
Authors: Rozati Roya , Tabasum Wajeeda , Ahmed Mohammed Sarosh , Khan Aleem Ahmed , Ahmed Talia Nazeer , Nayela Sumaiya , Azimi Salwa Sahar 
Published: January 2024

Objective: This study aims to determine the prevalence of endometriosis in women in South India, the epidemiological factors involved, and evaluate the symptomatic burden associated with it.
Design: A large-scale Hospital-based study was conducted among women of reproductive age (16 to 44 years) in the state of Telangana between March 2018 and March 2023. A randomized multi-stage stratified sampling method was adopted and included 2,400 women who were screened using a validated structured questionnaire. Patients presenting with symptoms indicative of endometriosis underwent additional assessment using abdominal ultrasonography (AUS) and serum cancer antigen 125 (CA125) tests. For confirmation, laparoscopy was offered to the patients who consented. Patients who declined laparoscopy were given the option of undergoing magnetic resonance imaging (MRI) instead.
Results: Among 2,400 women who participated, 60 women have been diagnosed with endometriosis during the 5-year study period. The prevalence of endometriosis was found to be 2.5%. The mean age of participants was 15.2 ± 3.5 years and the mean age at menarche was found to be 12.9 ± 1.1 years. Out of 60 participants diagnosed with endometriosis 30% (n = 18) experienced irregular menstrual cycles. Approximately 33.3% (n = 20) of the women reported experiencing Dysmenorrhea, with 28.4% (n = 17) complaining of dyspareunia. Among the cases with menstrual pain, exhibited ultrasound findings suggestive of endometriosis, with elevated CA125 levels observed in 45% (n = 27) of these cases. All 60 patients who consented to laparoscopic confirmation, exhibited positive histo-pathological evidence of endometriosis. The prevalence of endometriosis is found to be significant in women of reproductive age group and found to be associated with high rates of infertility in 15 (25%) patients. The results of this study showed that the prevalence of endometriosis is found to be 2.5% which is similar to the other studies reported. The severity of endometriosis during laparoscopy was assessed using the rAFS staging system, revealing rates of 55% and 45% for disease in Stages I & II, Stages III, & IV, respectively.
Conclusion: Our study concludes that endometriosis predominantly affects women in the reproductive age group and is often associated with primary infertility. The laparoscopic findings are identified as a standard tool for both diagnosis and treatment of endometriosis.
Peningkatan Kapasitas Kader Pendidikan keluarga Dan Penguatan Kelompok Tribina Dusun Karanganyar
Authors: Wijayanto Arif , Putri Maulida Anita 
Published: January 2024

Artikel ini mendeskripsikan tentang penjelasan terkait praktik pendidikan keluarga dalam kegiatan yang bertujuan untuk meningkatkan kapasitas kader dan penguatan kelompok tribina di Dusun Karanganyar. Tahapan pelaksanaan praktik meliputi perencanaan program, pelaksanaan program, dan evaluasi program. Metode yang digunakan adalah deskriptif kualitatif denganmenganalisis, menggambarkan, dan meringkas berbagai kondisi, situasi dari berbagai data yang dikumpulkan berupa hasil wawancara atau pengamatan mengenai masalah yang diteliti yang terjadi di lapangan. Hasil dari praktik ini adalah (1) Ketahanan keluarga menjadi bekal materi utama bagi para kader tribina, (2) Adanya inovasi program pembuatan websitekelompok tribina,(3) Permainan sederhana “Telepati Suit” menjadi permainan yang mampu membangkitkan semangat dan kekompakkan para kader.
Comparison of Political Dynasty in Indonesia and the United States
Authors: Maharani Andina Elok Puri , Baskara Arga , Suwadi Pujiyono 
Published: January 2024

Purpose: The aim of the research is to photograph political dynasties that occur in democratic countries by taking the examples of Indonesia and America.

Methods: The issue in this article is Political Dynasty in democratic countries. Political dynasties are built into a country's constitutional system. Its existence often triggers debate in societies that are studying ideal democracy. Political dynasties are considered to be the product of a political strategy to achieve victory.

Results and Conclusion: The research results show that the emergence of political dynasties is influenced by the actions of political elites who tend to pass on their positions of political power to the next generation or below. This happens because of the tendency to maintain power. Another reason is to continue the program that was initiated previously.

Research implications: Comparing political dynasties in Indonesia with the United States, the Indonesian state has a tendency to emerge random lytop down while in the United States it appears gradually bottom up.

Originality/value: In the above context, it is hoped that political elites will prioritize political processes and ethics in cadre formation.
PENGUATAN SENTRA HAK KEKAYAAN INTELEKTUAL (HKI) DI PERGURUAN TINGGI SEBAGAI UPAYA PERLINDUNGAN HUKUM TERHADAP KEKAYAAN INTELEKTUAL
Authors: Sinal Mohamad , Muqit Abd. , Himmah Dinda Rizqiyatul 
Published: January 2024

Hak Kekayaan Intelektual (HKI) merupakan hal yang sangat penting di bidang perdagangan internasional dan pembangunan ekonomi suatu negara. Hal ini dapat dibuktikan dengan dimasukannya perlindungan HKI ke dalam kesepakatan GATT (General Agreement on Tariffs and Trade) yang dikenal dengan Trade Related Aspects of Intellectual Property Right (TRIPs Agreement). Penelitian ini bertujuan untuk mengetahui (1) persepsi dosen dan mahasiswa terhadapat perlindungan hukum terhadap HKI, (2) persepsi dosen dan mahasiswa terhadap Sentra HKI sebagai upaya perlindungan hukum terhadap HKI, dan (3) upaya-upaya yang harus dilakukan oleh Polinema untuk meningkatkan persepsi dosen dan mahasiswa terhadap perlindungan hukum HKI dan Sentra HKI. Jenis penelitian ini adalah penelitian hukum empiris. Lokasi penelitian ini adalah Politeknik Negeri Malang. Populasi penelitian ini adalah mahasiswa dan dosen di lingkungan Politeknik Negeri Malang. Teknik pengambilan sampel dari populasinya dilakukan secara acak tanpa memperhatikan strata (Simple Random Sampling). Analisis data menggunakan metode deskriptif kualitatif dan kuantitatif. Temuan penelitian ini sebagai berikut; (1) responden dosen memiliki persepsi yang tinggi terhadap perlindungan HKI, sedangkan responden mahasiswa memiliki persepsi yang rendah terhadap perlindungan HKI; (2) responden dosen dan mahsiswa memiliki persepsi yang tinggi terhadap sentra HKI; dan (3) upaya yang dapat dilakukan meliputi sosialisasi dan edukasi HKI, matakuliah HKI diajarkan kepada mahasiswa, dan sinergi antarstakeholder.
PENEGAKAN HUKUM KASUS PELANGGARAN HAK LINTAS DAMAI KAPAL TANKER IRAN DAN PANAMA DI INDONESIA
Authors: Ramadhani Dewi Syara , Aswita Aswita , Zainuddin Moh. 
Published: January 2024

Kasus kapal pengangkut besar MT Freya dan MT Horse merupakan salah satu contoh pelanggaran hak lintas damai di perairan Indonesia. Pada tanggal 24 Januari 2021, Badan Keamanan Laut (Bakamla) saat memimpin pengawasan di sekitar Pulau Pejantan mendapati kedua kapal tersebut sedang melakukan kegiatan pemindahan muatan minyak mentah dari satu kapal ke kapal lainnya dalam kondisi berhenti di lautan, tepatnya di sekitar Pulau Pejantan, Kepulauan Riau. Permasalahan yang akan dibahas adalah bagaimana pedoman kebebasan memasuki wilayah perairan yang aman dalam UNCLOS 1982 dan bagaimana hak-hak bagain kepolisian yang aman bagi kapal pengangkut besar MT Freya dan MT Horse sesuai dengan peraturan yang berlaku di Indonesia. Teknik penelitian yang digunakan adalah metode penelitian hukum normatif yuridis dengan menggunakan pendekatan investigasi hukum dan kontekstual. Hasil penelitian menunjukkan bahwa pertama, pedoman hak lintas damai dalam UNCLOS 1982 diatur dalam Bagian II, Bagian 3 yang terdiri dari Pasal 17 – 32. Kedua, Majelis Hakim menjatuhkan pidana penahanan terhadap kapal MT Freya dan MT Horse selama 1 tahun, namun hukuman tersebut tidak perlu dilakukan dengan memaksakan waktu penilaian selama 2 tahun
An assessment of the relationship between body mass index and minor complications in percutaneous gastrostomy tubes
Authors: Lee Sean , Ghosh Abheek , Raymond Aislynn , Akhter Nabeel M. 
Published: January 2024

Objectives:
The aim of our study was to determine if patients with obesity have different postoperative outcomes than their peers.

Material and Methods:
A single-center retrospective review of all fluoroscopically-guided percutaneous gastrostomy tube, with 183 patients and 90 patients in the BAG and dilator groups, respectively. Patients were stratified, based on body mass index (BMI) percentile and for age. Demographic information and data on medical comorbidities and post-operative complications were collected. All analyses were conducted using Chi-square or Kruskal–Wallis testing.

Results:
The median BMI was 26.6 kg/m2 with a standard deviation of 7.7. 106 (38.8%) patients were classified in the normal BMI category, 57 (20.9%) were overweight, and 50 (28.3%) were classified as obese. No major complications were reported in either group. 106 patients (38.8%) reported minor complications. The most common complication observed across both groups was procedural pain, with a higher incidence in the balloon group compared to the dilator group (17.5% vs. 12.2%). Dislodgement emerged as the second most common complication, occurring more frequently in the balloon group (12%) compared to the dilator group (6.7%). When considering weight categories, the overall rate of minor complications was highest among underweight patients (57.6%, P = 0.124). Both underweight and normal BMI patients showed a significantly higher incidence of tube dislodgement compared to other BMI categories (27.2% and 9.4%, respectively, P = 0.015). In a multivariable logistic regression, age was associated with an increased risk of minor complications (odds ratio [OR] 1.03, F [1.01, 1.05], P = 0.002). BAG had a greater OR for minor complication rate compared to dilator-assisted gastrostomy, although the difference was not statistically significant (OR 1.19, 95% confidence interval [0.69, 2.06]).

Conclusion:
Few studies have identified the relationship between BMI and complications related to gastrostomy tube placement. Our study highlights the importance of individualized care for patients across different BMI classes to minimize complications and improve patient outcomes.
Multiple myeloma extramedullary relapse at the sellar and suprasellar region after autologous stem cell transplantation
Authors: De Jesus Orlando 
Published: January 2024

Background:
The effectiveness of autologous stem cell transplantation (ASCT) in preventing the development of central nervous system (CNS) plasmacytomas in multiple myeloma (MM) patients is not well understood. An ASCT patient who developed CNS extramedullary (EM) lesions is presented. The literature was reviewed for similar cases in which the transplant did not prevent the development of CNS lesions.

Case Description:
A 42-year-old female was evaluated after complaining of a sudden severe headache and complete vision loss. Two years before, she was diagnosed with MM and treated with systemic chemotherapy and an ASCT. The patient was in remission; however, a new brain magnetic resonance imaging showed a sellar and suprasellar mass. Additional smaller lesions were identified at the parietal convexity and the splenium. Due to the history of MM and evidence of multiple intracranial lesions, it was suspected that the lesions were secondary to EM disseminated disease. Due to the sudden loss of vision, the patient underwent a right frontotemporal craniotomy with subtotal sellar/suprasellar tumor resection to decompress the optic nerves. Histopathological examination of the lesion confirmed an immunoglobulin A (IgA) EM sellar and suprasellar plasmacytoma.

Conclusion:
In the majority of MM patients with CNS involvement, ASCT did not prevent the development of EM sellar plasmacytomas. The IgA subtype is associated with more aggressive disease biology for CNS relapses.
Pengaruh Pengembangan Sumber Daya Insani Terhadap Peningkatan Etos Kerja Karyawan Pada PT. Bank Muamalat KCU Medan Baru
Authors: Isnainia Ismi Mardhatillah  , Ahmad Afandi  
Published: January 2024

Etos kerja adalah cara pandang seseorang dalam menyikapi, melakukan dan bertindak dalam bekerja, dengan kemauan organisasi maupun perusahaan sehingga pekerjaan dapat dilaksanakan dengan baik. Oleh karena itu perlu adanya langkah untuk menyongsong dan membangun sikap etos kerja yang berkompeten dalam segala pelaksanaan yang berkaitan dengan instansi Bank salah satunya yaitu pengembangan sumber daya insani. Hal ini mendasari peneliti melakukan penelitian tentang pengaruh pengembangan sumber daya insani terhadap etos kerja karyawan. Penelitian ini bertujuan untuk melihat pengaruh pengembangan sumber daya insani terhadap etos kerja karyawan PT. Bank Muamalat KCU Medan Baru. Sampel dalam penelitian ini adalah seluruh karyawan PT. Bank Muamalat KCU Medan Baru yang berjumlah 23 orang dengan menggunakan teknik total sampling. Teknik analisis yang digunakan yaitu uji T, uji F dan koefesien determinasi. Berdasarkan analisis yang dilakukan bahwa hasil Pearson Correlation yang diperoleh sebesar 0,973 dengan nilai signifikan yaitu 0,00 < 0,05. Maka dapat digambarkan adanya hubungan yang erat antara pengembangan sumber daya insani dengan etos kerja karyawan di PT. Bank Muamalat KCU Medan Baru. Selanjutnya melalui hasil regresi linear sederhana diperoleh nilai F hitung = 359,092 dengan nilai signifikansi = 0,000. Karena nilai signifikasnsi < 0,05 maka disimpulkan bahwa pengembangan sumber daya insani memberikan pengaruh terhadap etos kerja karyawan PT. Bank Muamalat KCU Medan Baru. Kemudian melalui hasil nilai koefesien determenasi R2 (R Square) = 0,947. Kemudian dengan menggunakan rumus koefesien determenasi KD = R2 x 100 % maka didapatkan besar persentasi pengaruh pengembangan sumber daya insani dalam (X) dan etos kerja karyawan (Y) sebesar 94,7%. Dapat disimpulkan bahwa pengembangan sumber daya insani di PT Bank Muamalat KCU Medan Baru memberikan pengaruh yang signifikan terhadap etos kerja karyawan.
Perancangan Mesin Penetas Telur Unggas Otomatis Menggunakan Acci (Automatic Computer Control Incubator) Kapasitas 360 Butir
Authors: Haris Haris , Effiandi Nota , Afriyani Sicilia , Saputra Feri 
Published: January 2024

Proses penetasan telur unggas merupakan salah satu proses penting dalam budidaya peternakan unggas. Proses ini harus dilakukan dengan cermat dan teliti agar hasil penetasan dapat memuaskan. Namun, proses penetasan telur secara manual membutuhkan waktu dan tenaga yang cukup banyak dan terkadang belum efisien, sehingga dibuat rancangan alat penetas telur unggas otomatis kapasitas 360 butir. Alat ini menggunakan sistem pengontrolan yang dinamakan automatic computer control incubator. Tujuan dari penelitian ini adalah untuk merancang mesin penetas telur unggas otomatis yang digunakan untuk mempermudah dalam pengontrolan gerakan rak telur, suhu dan kelembaban udara. Proses perancangan dimulai dari survei lapangan untuk mengetahui kebutuhan alat yang akan dirancang dan kemudian dibuatlah desain dari mesin penetas telur unggas otomatis. Mesin ini berukuran 100 x 167 x 50 cm yang terdiri dari 6 (enam) buah rak untuk meletakkan telur unggas. Pada bagian atas mesin diletakkan kontroller inkubator untuk mengontrol secara otomatis pergerakan rak, suhu, dan kelembaban mesin
Between Genocide and War Crime – Legal-Cultural Analysis of the Russian Aggression in Ukraine
Authors: Siekiera Dr Joanna 
Published: January 2024

The cultural context, where two neighboring Slavic nations are in a state of war and the Russian imperialistic approach has never gone away for good, must be taken seriously into consideration. The international legal analysis of the Russo- Ukrainian war is not enough to truly understand the essence – rationale – of this armed conflict and then to find a solution to how to solve it and punish the perpetrator – the Russian Federation. The arguments gathered here by the author come from her own experience during trips to Russia and Ukraine, as well as military courses facilitation where students are taught that in modern warfighting it becomes more and more valid to change the (Western) lens and begin thinking as the perpetrator does. Only then we are objectively able to see and understand if the atrocities committed by Russian troops in Ukraine bear the hallmarks of a war crime or an act of genocide.
PENGARUH GAYA KEPEMIMPINAN TRANSAKSIONAL TERHADAP KINERJA KARYAWAN DENGAN MOTIVASI KERJA SEBAGAI MEDIASI PADA FARKHANSS TOWING SERVICE KOTA SURABAYA
Authors: Samudera Farkhan , Agustina Tri Siwi 
Published: January 2024

Dalam suatu perusahaan diperlukan senantiasa meningkatkan efektifitas terkait gaya kepemimpinan transaksional dalam perusahaan untuk dapat bertahan dan berkompetisi ditengah perubahan persaingan pasar dan lingkungan yang berkembang pesat Tujuan dari dilakukannya penelitian ini guna mengetahui signifikansi terkait gaya kepemimpinan transaksional mempengaruhi kinerja , motivasi dan terkait kinerja dengan motivasi sebagai mediasi..Dalam prosesnya, penulis menggunakan metode kuantitatif dengan media pengisian kuesioner dengan skala likert yang diisi oleh karyawan Farkhanss Towing Service yang kemudian data akan dianalisis dengan metode PLS-SEM dengan SmartPLS. Hasil penelitian didapatkan nilai T-statistics = 1,630 dan p-value = 0,104 yang artinya tidak adanya pengaruh positif pada Gaya Kepemimpinan dengan Kinerja Karyawan. Selanjutnya, pengaruh Motivasi terkait Kinerja Karyawan memiliki nilai T-statistics = 3,144 dan p-value = 0,002 yang dapat disimpulkan bahwa adanya pengaruh positif Motivasi terkait Kinerja Karyawan.
In vitro assessment of thrombolytic potential of red and white ginger (Zingiber officinale)
Authors: Pinontoan Reinhard , Leke Patricia Ansyra Injilia , Lesmana Jevon Aaron , Purnomo Jonathan Suciono , Dikson Dikson , Samantha Ariela 
Published: January 2024

Background: Cardiovascular diseases (CVDs) are a leading cause of death, and their pathogenesis is commonly attributed to thrombosis. Although existing medications are effective and fast-acting for thrombosis management, they tend to be expensive and cause severe side effects. Plant-based thrombolytic agents are actively sought after as inexpensive and safe alternatives for the treatment and prevention of thrombosis. Red ginger (Zingiber officinale var. rubrum) and white ginger (Zingiber officinale var. officinale) are widely used in foods and beverages and are believed to confer a wide variety of health benefits. Objective: This study aims to elucidate the thrombolytic and fibrinolytic potential of red and white ginger extracts in vitro.Methods: In this study, in vitro analyses were performed using erythrocyte liberation, euglobulin degradation, fibrin degradation, and fibrin zymography assays. The ability of crude enzyme extracts from both red (rgEx) and white ginger (wgEx) to degrade blood clots was analyzed using the erythrocytes liberation assay. Then, the thrombolytic and fibrinolytic activities of rgEx and wgEx were evaluated using euglobulin and fibrin degradation assays, both of which were visualized using Sodium Dodecyl Sulfate Polyacrylamide Gel Electrophoresis (SDS-PAGE). Finally, fibrinolytic enzymes were identified using a fibrin zymography assay. Results: Red and white ginger extracts were found to have strong thrombolytic properties via high total liberated erythrocyte count from the erythrocyte liberation assay. The ginger extract proteases can rapidly degrade euglobulin and fibrin, with their priority order beginning with A
Burden of Disease of Duchenne Muscular Dystrophy in Denmark – A National Register-Based Study of Individuals with Duchenne Muscular Dystrophy and their Closest Relatives
Authors: Rudolfsen Jan Håkon , Vissing John , Werlauff Ulla , Olesen Charlotte , Illum Niels , Olsen Jens , Poulsen Peter Bo , Strand Mette , Born Alfred Peter 
Published: January 2024

Background: Duchenne Muscular Dystrophy (DMD) is a progressive genetic disease with a prevalence of 1 per 3,600–6,000 male births. Individuals with DMD are typically diagnosed at age 4–7 years; median survival is 30 years. They require multidisciplinary care, personal assistance, and often special education. Objective: The aim was to assess the burden of disease in DMD in Denmark. This includes incidence, prevalence, use of healthcare services, labour market participation, educational outcomes, and overall attributable costs due to DMD. Impact on the closest relatives (siblings and parents) was also investigated. Methods: The comprehensive Danish national health and administrative registers were used to assess the burden of disease following individuals with DMD and closest relatives from five years before, and up to 20 years after DMD diagnosis. Individuals with DMD (and relatives) from 1994–2021 were included. All outcomes were compared to matched control groups without the disease drawn from the Danish population. Results: 213 unique individuals with DMD were identified. They had lower grades in school, required more special education and more healthcare and home care compared to their control group. The extra costs of special education summed to EUR 180,900 over the course of 11 years elementary school. They had an annual average productivity loss of EUR 20,200 between the age of 18 to 30. The extra healthcare costs of DMD in the 20 years after diagnosis were estimated to EUR 1,524,000. If an individual with DMD lives to be 30, total extra costs sum to EUR 2,365,800. Conclusions: Using national register data this study presented detailed results on the burden of disease of DMD, including impact on closest relatives. With 60 additional hospital admissions and 200 extra outpatient contacts in 20 years healthcare costs, but also costs of home care and special education, increases as disease progresses.
PELATIHAN DAN SOSIALISASI UJI SERTIFIKASI KOMPETENSI TEKNIS BNSP SEBAGAI SARANA PENINGKATAN KOMPETENSI KEAHLIAN
Authors: Rianto Bayu , Jalil Muhammad , Chrismondari  , Muni Abdul , Sudeska Endy 
Published: January 2024

Sertifikasi kompetensi adalah proses pemberian sertifikat yang dilakukan secara sistematis dan obyektif melalui asesmen kompetensi yang mengacu kepada standar kompetensi kerja nasional, standar internasional, dan/atau standar khusus lainnya. Pelaksanaan asesmen kompetensi telah diatur pemerintah Indonesia melalui Peraturan Pemerintah (PP) No. 10 Tahun 2018 yang menugaskan Badan Nasional Sertifikasi Profesi (BNSP) sebagai lembaga yang bertugas untuk memastikan pengembangan kompetensi di Indonesia. Berdasarkan kebijakan tersebut, BNSP merupakan lembaga yang sah dan berwenang untuk menerbitkan sertifikasi kompetensi. Sertifikat kompetensi yang diterbitkan oleh BNSP sesuai dengan hasil uji sertifikasi yang diselenggarakan oleh Lembaga Sertifikasi Profesi (LSP) terlisensi. Tujuan kegiatan pengabdian masyarakat ini adalah memberikan sosialisasi dan pelatihan skema sertifikasi teknis BNSP dimana Kegiatan ini ditujukan untuk karyawan/pegawai atau calon karyawan/pegawai di instansi atau perusahaan, serta lulusan SMK Sederajat, alumni dan mahasiswa. Kegiatan dilakukan dengan melakukan sosialisasi dan pendampingan kepada calon peserta uji kompetensi. Diharapkan kegiatan ini dapat memberikan manfaat atas permasalahan yang secara umum sering dihadapi terkait pemahaman mengenai skema sertifikasi teknis dari LSP dan BNSP.