bluuebunny/crossref_metadata_2025_split huggingface dataset:
Just energy transition: Navigating Poland’s transition away from coal mining
Authors: Martin Marilen , Broughel Anna 
Published: February 2025

Abstract
This perspective paper analyses Poland's transition from coal mining, focusing on Upper Silesia – home to the EU's largest coal mining workforce, with 78,500 direct mining jobs and an additional 21,000 indirect jobs at stake. Drawing upon original data analysis and existing literature, the paper examines the complex relationship between the coal phase-out and demographic decline at the powiat (county) level. While projected population decline could partially offset job losses from mine closures, the effects vary dramatically across powiats - from potential unemployment reaching 20.27 percent in Bieruńsko-Lędziński powiat to projected labor shortages in areas like Bytom and Zabrze. Despite a significant decrease in job opportunities in coal mining, averaging a 7.85 percent decline across affected powiats, there is a considerable likelihood that other industries will encounter labor scarcities. Second, the impact extends beyond direct mining employment - contractors and service providers are particularly vulnerable, with 70 percent of the 1,054 identified contracting companies dependent on a single mine. Third, retraining faces specific barriers: miners strongly resist relocation, are reluctant to accept wage reductions and show limited interest in solar and wind energy sectors, suggesting energy efficiency, automotive, and ICT sectors as better alternatives. The paper demonstrates that successful transitions require understanding local contexts, from workers' skill transferability to transportation infrastructure to fiscal capacity. These insights from Silesia offer valuable lessons for both developed economies managing industrial transitions and emerging economies seeking to balance economic development with decarbonization.
Neuromorphic Devices Assisted by Machine Learning Algorithms
Authors: Huo Ziwei , Sun Qijun , Yu Jinran , Wei Yichen , Wang Yifei , Cho Jeong Ho , Wang Zhong Lin 
Published: February 2025

Abstract
Neuromorphic computing extends beyond sequential processing modalities and outperforms traditional von Neumann architectures in implementing more complicated tasks, e.g., pattern processing, image recognition, and decision making. It features parallel interconnected neural networks, high fault tolerance, robustness, autonomous learning capability, and ultralow energy dissipation. The algorithms of artificial neural network (ANN) have also been widely used because of their facile self-organization and self-learning capabilities, which mimic those of the human brain. To some extent, ANN reflects several basic functions of the human brain and can be efficiently integrated into neuromorphic devices to perform neuromorphic computations. This review highlights recent advances in neuromorphic devices assisted by machine learning algorithms. First, the basic structure of simple neuron models inspired by biological neurons and the information processing in simple neural networks are particularly discussed. Second, the fabrication and research progress of neuromorphic devices are presented regarding to materials and structures. Furthermore, the fabrication of neuromorphic devices, including stand-alone neuromorphic devices, neuromorphic device arrays, and integrated neuromorphic systems, is discussed and demonstrated with reference to some respective studies. The applications of neuromorphic devices assisted by machine learning algorithms in different fields are categorized and investigated. Finally, perspectives, suggestions, and potential solutions to the current challenges of neuromorphic devices are provided.
Conclusion
Authors: Hartmann Catherine 
Published: February 2025

Abstract
Reflecting on passages from the novel We Measure the Earth with Our Bodies by Tsering Yangdzom Lama, the Conclusion brings together the themes of the preceding chapters to reaffirm the main thesis of the book. It reiterates the argument that Tibetan pilgrimage texts encode practices of seeing that engage pilgrims’ perception both of the ordinary material world and of the extraordinary, envisioned world, thus using vision as a site of transformation. These practices of seeing aim to reshape pilgrims’ perception of the holy mountain and their experience of the world. Next, the Conclusion argues that the particular practices of Tibetan pilgrimage literature expand our understanding of how religious traditions enable practitioners to experience that which is ordinarily invisible and inaccessible as real. This, in turn, shows that seemingly fantastical religious worldviews are not simply believed or taken for granted, but actively constructed and reconstructed for new generations of practitioners.
Spinoza’s Definition of Faith
Authors: Gartenberg Zachary Micah 
Published: February 2025

Abstract
One of the most pivotal yet under-examined moments in Spinoza’s Theological-Political Treatise is his attempt to define the notion of ‘faith’. This essay unpacks Spinoza’s understanding of his definition and its significance within the broader argument of the Treatise by carefully analyzing the relationship between the definition’s terminology and logical structure. It specifically examines the connection Spinoza draws between faith and obedience, arguing that, according to Spinoza’s definition, conceiving of obedience implies conceiving of faith and not the other way around (as many commentators have claimed). It explores the implications of this entailment for interpreting the nature and function of Spinoza’s ‘dogmas of universal faith’. Spinoza claims that the definition of faith ultimately grounds his main argument in the Treatise, which makes the case for a radical separation between ‘faith’ and ‘philosophy’. One of the goals of this essay is to bring out in higher resolution how the definition underwrites this argument, and what it ultimately means.
Incidence, stage and outcome of melanoma, keratinocyte and other cancers in individuals with vitiligo or alopecia: intraindividual or familial risks?
Authors: Delcoigne Benedicte , Lysell Josefin , Askling Johan 
Published: February 2025

Abstract

Background
Vitiligo and autoimmune alopecia (AA) are caused by T-cell mediated autoimmunity in genetically predisposed individuals. Studies in vitiligo have reported reduced risks for melanoma (MM), some also for keratinocyte skin cancer (KC). In AA, reduced risks for KC (and also MM) have been reported. The driving mechanisms (genetic predisposition, immunological or other effects of the disease phenotypes, or environmental) remains unclear. Whether the immune-related genetic predisposition in vitiligo and AA offers “inherent” protection against other types of cancer remains unresolved.

Objectives
To investigate the incidence and outcome of MM, squamous cell skin cancer (SCC) and non-cutaneous cancers in vitiligo and alopecia, vs. that in the general population, and to investigate the corresponding risks in their siblings.

Methods
We performed a population-based matched cohort study using data from linkage of Swedish registers. We used Cox proportional hazards regression to calculate hazard ratios (HR) contrasting patients with vitiligo or AA and the general population, and contrasting their siblings.

Results
Between 2006 to 2021, we included 15,030 patients with vitiligo, 18,541 with alopecia, and 17,853 and 21,821 of their siblings. Based on 17 MM events (crude incidence per 100,000, IR: 16), 23 SCC events (IR: 22) in vitiligo, and, 20 MM (IR: 15) and 24 SCC (IR: 18) in AA, the HR for MM was 0.53 (95%CI 0.32-0.86) in vitiligo and 0.53 (95%CI 0.34-0.83) in AA. Regarding SCC, HRs were 0.81 (95%CI 0.53-1.24) in vitiligo and 0.65 (95%CI 0.43-0.98) in AA. Stage at diagnosis of MM didn’t differ substantially between patients and the general population. Among siblings, HRs for MM and SCC were not statistically significantly altered (0.82 ≤ HR ≤ 1.10). In patients and their siblings, HRs for non-cutaneous solid or hematological cancers were not reduced.

Conclusion
In vitiligo and in AA the decreased risk of cutaneous cancers extends beyond the cell-type targeted by the autoimmune reaction. The general tendency towards somewhat reduced skin cancer risks among their siblings suggests a role for other factors than the disease phenotypes per se. Neither the vitiligo and AA phenotypes nor their immune-related genetic predispositions seem to offer any “inherent“protection against non-cutaneous malignancies.
Polymorphism and Memory Mechanochromic Emission of a Novel Molecular Fluorophore, 1-Cyano-1-(2-naphthyl)-2-[4-(diphenylamino)phenyl]ethylene
Authors: Shimazaki Yuito , Kurita Rikuya , Nakano Hideyuki 
Published: February 2025

Abstract
A titled molecular fluorophore (DPACNA) has been designed and synthesized. In addition to glass formation, DPACNA was found to exhibit polymorphism taking two distinct crystal structures. Both crystalline forms and the amorphous film exhibited fluorescence with different emission spectra from each other. The spectra of both crystals changed to the same spectra as for the amorphous film by grinding the crystals. Interestingly, the resulting ground samples remembered their original crystalline states and could be restored by fuming or annealing.
The 60:40 conundrum: are women with CKD discriminated after referral to a nephrology clinic?
Authors: Vautcranne Adele , Bianco Lavinia , Maze Beatrice , Fois Antioco , Chatrenet Antoine , Moio Maria Rita , Santagati Gulia , Njandjo Linda , de Müllenheim Pierre-Yves , Torreggiani Massimo , Piccoli Giorgina Barbara 
Published: February 2025

Abstract

Background
Epidemiological data show that chronic kidney disease (CKD) is more prevalent among females than males but the prevalence of women in dialysis is lower, as is their representation in nephrology trials. We aimed to test whether sex distribution varies at nephrology referral, inclusion in a trial or at the starting of dialysis.

Methods
We evaluated patients’ characteristics at the time of the first consultation in the Unit for the Care of Advanced CKD (UIRAV), at the inclusion in an observational study (PRO-RE-RE-PRO) and at the beginning of dialysis. Patient and renal survival analysis was performed in the pre-dialysis phase and after dialysis start. Reasons for denying participation to the proposed study and causes of death or withdrawal from follow-up and dialysis were likewise examined.

Results
During the period 2017–2023, 866 patients were referred to the UIRAV, 59% males and 41% females. Female patients were older, had lower comorbidity and were referred at the same eGFR than males. The same males/females proportion was observed in patients included in the PRO-RE-RE-PRO study and at dialysis start. Survival was significantly higher in females. Overall, distribution across sex remained stable over time.

Conclusions
Males and females are referred at similar eGFR levels, which appears to be the main reason for seeking nephrology care. Afterwards, the ratio between males and females remains stable, suggesting that if a sex-selection bias exists, it should be sought before the first nephrology referral. However, further studies are needed to ensure that health equity is respected across sexes.
Left atrial veno-arterial extracorporeal membrane oxygenation (LAVA-ECMO) as a bridge to surgical or percutaneous closure of post-myocardial infarction ventriculoseptal defects (MI-VSD): A Case Series
Authors: Fadel Raef , Elderkin Jessica , Alrayes Hussayn , Giustino Gennaro , Frisoli Tiberio , Basir Mir Babar , Apostolou Dimitrios , Villablanca Pedro 
Published: February 2025

Abstract

Background
Post-myocardial infarct (MI) ventricular septal defect (VSD) is a rare and severe complication of an acute MI with high mortality rate. The use of veno-arterial extracorporeal membrane oxygenation (VA-ECMO) as a bridge to surgical or percutaneous repair in cardiogenic shock secondary to post-MI VSD has been published, but is limited to small case series primarily utilizing surgical ECMO, with the main drawback of potentially increasing afterload and left ventricle pressure, further worsening VSD shunting. Left-atrial VA-ECMO (LAVA-ECMO) can potentially absolve this concern given it utilizes bi-atrial drainage through a trans-septal fenestrated cannula.

Cases
5 patients were included in this series, all with VSD secondary to MI, and all managed with LAVA-ECMO as a bridge to repair. Average age was 62 ± 4.2 years, body mass index of 29.4 ± 4.5 kg/m2, and left ventricular ejection fraction of 46.6 ± 13.8%. Hemodynamics monitoring pre- and post- LAVA ECMO demonstrated improvement in right atrial, right ventricular, pulmonary, left atrial, and left ventricular pressures (figure 1). Average time to repair was 7.4 ± 3.9 days. All 5 patients survived to repair, with 4 undergoing surgical and 1 undergoing percutaneous closure. 4 out of 5 patients were decannulated successfully.

Discussion
This case series reports the successful use of LAVA-ECMO as a bridge to MI-VSD repair in patients with cardiogenic shock. LAVA-ECMO serves as a convenient approach to managing patients with MI-VSD related cardiogenic shock as it is implanted percutaneously, and can be done at the time of shock diagnosis, during right heart catheterization by trained interventionists.
Successful catheter ablation for sustained ventricular tachycardia in right ventricular infarction after surgery for giant right coronary artery aneurysm. A case report
Authors: Watanabe Ken , Fukui Akio , Aono Tomonori , Aita Satoshi , Matsui Motoyuki 
Published: February 2025

Abstract

Background
Post-infarction scar-related ventricular tachycardia (VT) originating from the right ventricular (RV) free wall in patients with RV infarction is rare.

Case summary
A 75-year-old Asian male, with a history of RV infarction after surgery for a giant right coronary artery aneurysm, presented with sustained ventricular tachycardia (VT) with left bundle branch block and inferior axis morphology. The activation mapping during the VT revealed a focal origin initially propagated from the anterior attachment of the RV wall, and mid-diastolic potentials (MDPs) were detected within the RV free wall close to the anterior attachment. At the MDPs recording site, entrainment pacing showed concealed entrainment. The stimulus-QRS interval was equal to the local electrogram-QRS interval. Successful termination of clinical VT was achieved through radiofrequency delivery targeting the MDPs during the VT. Voltage mapping during sinus rhythm (SR) demonstrated a scar area at the RV free wall. Delayed potentials (DPs) during SR were obtained at the zone of MDPs recorded. Additional ablation was performed to eliminate the DPs, resulting in no further inducibility of VT with programmed stimulation.

Discussion
RV free wall infarction can lead to scar-related arrhythmogenesis. Detailed electrophysiological and functional mapping of such scar areas proved effective in terminating VT.
An experimental study of the elastic properties of the sandstone flooded with supercritical CO₂: The influences of saturation, pressure, and temperature
Authors: Zhao Luanxiao , Zhao Yaxi , Song Xuehang , Wang Yirong , Chen Yuanyuan , Zhu Zhenyu , Yang Renfeng , Geng Jianhua 
Published: February 2025

Summary
Geological storage of captured CO₂ is essential for reducing anthropogenic greenhouse gas emissions and ensuring the sustainable use of fossil fuels. Understanding the influence of saturation, pressure, and temperature on the elastic properties of brine-saturated sandstone flooded with supercritical CO₂ is critical for interpreting seismic and sonic logging data, which aids in monitoring and quantifying subsurface changes associated with CO₂ injection. The experimental results indicate that as scCO₂ saturation increases (0∼60 per cent), the P-wave velocity decreases significantly with an average of 14 per cent drop, while the S-wave velocity increases slightly. Temperature variations (80–110°C) have a minimal effect on both velocities (1∼2 per cent), whereas elastic features show noticeable sensitivity to the variation of confining pressure (20-30 MPa) and pore pressure (10-20 MPa). Ignoring the effects of pore pressure might lead to the bias of interpreting seismic data for monitoring scCO₂ saturation change. The constructed rock physics models well capture the coupled effects of porosity and scCO₂ saturation on the P-impedance and P- and S-wave velocity ratio, which show good agreement with the experimental results. These findings are crucial for improving monitoring methods and enhancing the accuracy of predictive models for CO₂ geological storage.
Wetland ecosystem services and their spatial scales of benefit in an urban environment: A case study of varanasi, India
Authors: Kushwaha Prashant , Sanyal Srabani , Verma Shivam 
Published: February 2025

Abstract
Wetlands are valuable terrestrial ecosystems because they perform diverse ecosystem functions and provide significant benefits to humanity. These benefits, collectively termed ecosystem services, are essential for human survival, particularly in densely populated urban areas. However, wetlands often face neglect due to a lack of awareness among citizens and governments regarding their significance. We assessed the ecosystem services offered by the wetlands of Varanasi, one of the oldest living cities, and elucidate the spatial scales wherein these services are delivered. Field visits, personal observations, and interviews based on the Rapid Assessment of Wetland Ecosystem Services (RAWES) approach, were used to evaluate 27 ecosystem services across 12 wetlands. The ecosystem services of water regulation and local climate regulation had high positive count value inferring highly beneficial contributions to human well-being, whereas pest regulation and regulation of human disease, had negative count value indicating an adverse impact on human well-being, primarily due to the polluted state of the city's wetlands. Supporting services with an Ecosystem Services Index (ESI) of 0.55 made a substantial positive impact on human well-being, while provisioning services made minimal contributions (ESI = 0.12). The analysis of the spatial scale of ecosystem service benefits indicated that the distribution of ecosystem services is highly Varanasi-centric. To provide a comprehensive representation of both the importance scale and the spatial scale of benefit, the Spatial Ecosystem Services Index (Spatial ESI) was developed. Cultural services scored the highest Spatial ESI of 0.17 while provisioning services have the lowest Spatial ESI (0.03).
Comparative evaluation of disc diffusion and Liofilchem™ MTS strip methods with broth microdilution for cefepime/enmetazobactam susceptibility testing
Authors: Emeraud Cécile , De Swardt Hippolyte , Bernabeu Sandrine , Latour Lena , Pages Alice , Ronsin Sarah , Bonnin Rémy A , Dortet Laurent 
Published: February 2025

Abstract

Background
Cefepime/enmetazobactam is a newly approved β-lactam/β-lactamase inhibitor combination with promising activity against MDR Gram-negative Enterobacterales, particularly ESBL- and OXA-48-producing isolates. Reliable susceptibility testing methods are essential to guide its clinical use.

Objectives
To evaluate the performance of two commercial cefepime/enmetazobactam susceptibility testing methods, disc diffusion and Liofilchem™ MTS gradient strips, using broth microdilution (BMD) as the gold standard.

Methods
A total of 291 carbapenem-resistant Enterobacterales isolates, including 194 carbapenemase producers, were included. Susceptibility testing was performed using BMD, disc diffusion and Liofilchem™ MTS strips. Results were interpreted following EUCAST and FDA 2025 breakpoints. Essential agreement (EA) and bias were calculated for gradient strip methods according to the ISO 20776-2021 guideline, whereas categorical agreement (CA), very major errors (VMEs) and major errors (MEs) were determined for disc diffusion according to the ISO 20776-2:2007 guideline.

Results
The disc diffusion method demonstrated high CA (93.8% EUCAST, 95.9% FDA). VME rates exceeded acceptable thresholds using EUCAST breakpoints (20.8%) but were within limits for FDA (1.9%). Liofilchem™ MTS strips achieved 88.3% (95% CI: 84.1%–91.5%) EA and a bias of −8.9%. Both methods accurately detected susceptibility in OXA-48-producing isolates but showed limitations for isolates close to the MIC breakpoints.

Conclusions
Disc diffusion and Liofilchem™ MTS strips represent reliable alternatives to BMD for routine cefepime/enmetazobactam testing.
Global epidemiology of high priority and pandemic Pseudomonas aeruginosa in pets, livestock, wild and aquatic animals: A systematic review and meta-analysis
Authors: Abdullahi Idris Nasir , Mejri Sirine , Okwume Chukwudi Cresent , Lawal Nurudeen Adedeji , Olusegun Olatunde A , Sallem Rym Ben , Slama Karim Ben 
Published: February 2025

Abstract
High-priority and international high-risk Pseudomonas aeruginosa (PA) are public health emergent strains. Here, we performed the first systematic review and meta-analysis of studies that reported the frequency of PA, carbapenem (CARBR), and colistin (COLR) resistant P. aeruginosa (PA) in healthy and sick livestock (A), pets (B), wild (C), and aquatic animals (D) from January 2013 to January 2023. Following the PRIMSA guidelines, 57 cross-sectional and eight prospective studies were found eligible. Random-effect models were used to determine the pooled prevalences. Phylogenetic analyses based on core-genome single nucleotide polymorphisms (SNPs) were performed using CSI Phylogeny 1.4. The overall pooled prevalence of PA, COLR-PA, and CARBR-PA were 18.6%, 4%, and 11.7%, respectively. Wild animals had the highest pooled prevalence of PA, 33.5%. The pooled prevalence of COLR was significantly higher in PA strains from sick than healthy animals (p&lt;0.0001). Furthermore, COLR was significantly highest in PA strains from wild animals, 9.8% (95% CI: 0.8-58.9) while CARBR was highest in PA strains from pets, 14.8% (95% CI: 6.7-29.8). Seven (ST235, ST111, ST233, ST244, ST357, ST308, ST277) of the 10 high-risk CARBR−PA clones carrying ExoU/T/S were reported in animals. The SNP-based phylogenetic analysis of 23 genomes of CARBR-PA from animals obtained from publicly available databases revealed two closely related blaGES-carrying strains (&lt;100 SNPs) in sick pets, suggesting a transmission event. A higher frequency of high-risk carbapenem than colistin-resistant PA strains exists in animals. These findings highlight the roles of different animal species, especially pets and wild animals in the persistence and dissemination of high-priority P. aeruginosa.
FuSViz—visualization and interpretation of structural variation using cancer genomics and transcriptomics data
Authors: Zhao Sen , Nakken Sigve , Vodak Daniel , Hovig Eivind 
Published: February 2025

Abstract
Structural variation (SV) is a frequent category of genetic alterations important for understanding cancer genome evolution and revealing key cancer driver events. With the development of high-throughput sequencing technologies, the ability to detect SVs of various sizes and types has improved, at both the DNA and RNA levels. However, SV calls are still prone to a considerable fraction of false positives, which necessitates visual inspection and manual curation as part of the quality control process. Identification of reliable and recurrent SVs in larger cohorts lends strength to revealing the driving roles of SVs in cancer development and to the discovery of potential diagnostic and prognostic biomarkers. Here, we present FuSViz, an application for visualization, interpretation, and prioritization of SVs. The tool provides multiple data view approaches in a user-friendly interface, allowing the investigation of prevalence and recurrence of SVs and relevant partner genes in a sample cohort. It integrates SV calls from DNA and RNA sequencing datasets to comprehensively illustrate the biological impact of SVs on the implicated genes and associated genomic regions. The functionality of FuSViz is intended for interrogation of both recurrent and private SVs, effectively assisting with pathogenicity evaluation and biomarker discovery in cancer sequencing projects.