bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sexual and Reproductive Health in the Management of Epilepsy
Authors: Bensalem-Owen Meriem K. 
Published: February 2025

ABSTRACT

OBJECTIVE
The management of epilepsy should be patient centered, and the treating team should carefully balance eliminating seizures while minimizing adverse effects associated with antiseizure medications. This article highlights important aspects of care related to sexual and reproductive health in people with epilepsy.

LATEST DEVELOPMENTS
Gender- and sex-based management in epilepsy can present unique challenges especially in people with epilepsy of childbearing potential. One of the most important considerations with the prescription of antiseizure medications to people of childbearing potential involves reproductive health. Folic acid supplementation is recommended to reduce the risk of congenital malformations, but there is no consensus on the optimal dose. The clinical management of pregnancy in the setting of epilepsy can be challenging. Significant knowledge gaps remain regarding the risks for most new antiseizure medications, neurostimulation therapy, and ketogenic diets during pregnancy. Ongoing multicenter pregnancy registries continue to inform practitioners on the medical treatment of people with epilepsy of childbearing potential. Data evaluating the effect of antiseizure medications on male patients with epilepsy, especially around conception, continue to be insufficient.

ESSENTIAL POINTS
The decision to prescribe an antiseizure medication depends on several considerations because of the potential for lifetime treatment with a daily medication. It is important to tailor management to the patient’s specific circumstances. Seizures and antiseizure medications can both affect sexual and reproductive health. Furthermore, hormone fluctuations may affect seizure frequency, treatment, and contraception. All these factors should be considered when treating people with epilepsy during their reproductive years. In addition, it is important to foster a multidisciplinary approach for the treatment of people with epilepsy.
A Multidisciplinary Approach to Nonepileptic Events
Authors: Patron Victor , Bermeo-Ovalle Adriana C. 
Published: February 2025

ABSTRACT

OBJECTIVE
This article provides a guide for neurologists managing nonepileptic events (NEEs), a complex intersection of neurology and psychiatry. It covers risk factors, pathophysiology, current treatment approaches, and prognosis, with specific management strategies for challenging scenarios such as patients with intellectual disabilities and comorbid epilepsy.

LATEST DEVELOPMENTS
An emphasis on strong communication and coordinated care among health care specialists improves patient outcomes and reduces unnecessary medical consultations and procedures. This approach is now recognized as essential for addressing the complex presentation and comorbidities associated with NEEs.

ESSENTIAL POINTS
NEEs are prevalent and highly disabling, and multiple pathophysiologic mechanisms for these events have been proposed. Mortality is comparable with that of patients with treatment-refractory epilepsy, and prognosis is better for children than adults. Achievable treatment goals for adults include improved quality of life and reduced frequency and severity of events, even if complete remission of NEEs is not achieved. Enhanced communication and coordinated care through multidisciplinary care teams enable the efficient use of individual expertise at different treatment stages to address the presentation, risk factors, and comorbidities associated with NEEs, resulting in a better quality of life for patients.
Diversity and Underserved Patient Populations in Epilepsy
Authors: Clarke Dave F. 
Published: February 2025

ABSTRACT

OBJECTIVE
Despite advancements in epilepsy management, disparities and lack of inclusion of many people with epilepsy are associated with increased morbidity and mortality. Compounding these problems is the paucity of diversity among health care providers, research participants, and researchers. This issue as well as potential solutions are explored in this article.

LATEST DEVELOPMENTS
Prompted by recent social justice incidents, patient advocacy groups, epilepsy societies, and governing bodies such as the National Institute of Neurological Disorders and Stroke, US Centers for Disease Control and Prevention, and the Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders have proposed initiatives to improve disparities in epilepsy care. Public health epilepsy research continues to expose deficiencies and disparities. Increased awareness of health care gaps and technologic advances should help foster improved epilepsy health equity and inclusivity.

ESSENTIAL POINTS
To deliver timely, effective care for people with epilepsy, we must be knowledgeable of sociodemographic obstacles to access. These include confounding factors such as historical determinants, unconscious bias, and lack of diversity. Improving awareness and promoting diversity in research participation can advance treatment for underserved populations and improve trust.
Nonresident Parent Wealth Among Children
Authors: Hays Jake , Fomby Paula 
Published: February 2025

Abstract
Wealth matters for children's well-being. However, most research has considered only the wealth held in children's resident households, even though more than one quarter of U.S. children have a parent living elsewhere. We provide the first national estimates of nonresident parent wealth among children who ever lived with both parents in a shared household. We use the Panel Study of Income Dynamics (1984–2021)—whose survey design enables us to produce unbiased estimates with respect to factors that condition access to nonresident parents—to describe the characteristics of nonresident parent wealth, children's potential access to it, and its contribution to educational attainment. We find that nonresident parent wealth varies substantially and that the rank–rank correlation between nonresident and resident parent wealth is roughly .3. Nonresident parent wealth is positively predictive of more frequent parent–child contact, more consistent and higher value child support payments, and children's bachelor's degree attainment, suggesting that it is related to multiple domains of parenting and child well-being. The findings demonstrate that accounting for the spread of resources across households, but within a family system, is critical to understanding broader patterns of inequality in American family life.
The Time beneath the Concrete
Authors: Abourahme Nasser 
Published: February 2025

In The Time beneath the Concrete, Nasser Abourahme argues that settler colonialism is always as much an attempt to conquer time as it is to conquer land. Taking as his primary object Palestinian refugee camps, created in the fallout of the eliminatory violence of Israel’s founding, Abourahme shows how these camps become the primary place where settler colonial attempts to dominate space and time encounter Indigenous refusal. Seen from the camps, Israel becomes a settler colonial project defined by its inability to move past the past—a project stuck at its foundational moment of conquest. At the same time, the Palestinian insistence on return is a refusal to abide by the closure of the past into settler futurity. Palestinian struggle does not just happen in the open time of dispossession; it happens over this time. That struggle, Abourahme demonstrates, is a form of anticolonial refusal that draws its power not from any decisive finality, but precisely from irresolution and keeping time open.
Duke University Press Scholars of Color First Book Award
Joint Associations of Moderate-to-Vigorous Physical Activity and Sedentary Time with Adiposity and Cardiometabolic Risk Factors in Adolescents
Authors: Suárez-Reyes Mónica , Beyl Robbie A. , Katzmarzyk Peter T. , Staiano Amanda E. 
Published: February 2025

ABSTRACT

Purpose
This study aims to explore the joint associations of moderate-to-vigorous physical activity (MVPA) and sedentary time (ST) with adiposity and cardiometabolic risk factors in adolescents.

Methods
A cross-sectional study was conducted on 309 participants (10-16 years old). Measurements included accelerometer-measured MVPA and ST, anthropometrics, body composition, and cardiometabolic risk factors. MVPA and ST were categorized as high or low based on median values (MVPA 27.7 min/day, ST 597.7 min/day). General Linear Models assessed associations of MVPA and ST with adiposity and cardiometabolic risk factors, adjusted for covariates.

Results
We observed significant inverse associations between MVPA and adiposity measures. Thus, participants in the Low MVPA category, compared to those in the High category, had higher BMI (2.23 units), z-BMI (0.43 units), waist circumference (6.1 cm), fat mass (4.6 kg), body fat (3.9%) and visceral fat (0.13 L), indicating that higher MVPA is linked to healthier body composition. No significant associations were found between ST and adiposity. MVPA was also negatively associated with some cardiometabolic risk factors, whereas ST showed no significant associations.

Conclusions
This study highlights the need to prioritize increasing MVPA among adolescents to support healthy body composition and improve cardiometabolic health. Although ST did not show significant associations, it remains important to limit sedentary behaviors due to their potential contribution to negative health outcomes later in life.
The Accumulation of Performance Fatigue and Perceptual Responses across Consecutive High-Intensity Interval and Constant-Load Cycling Sessions
Authors: Zhang Jenny , MacDougall Keenan B. , McClean Zachary J. , MacIntosh Brian R. , MacInnis Martin J. , Aboodarda Saied Jalal 
Published: February 2025

ABSTRACT

Introduction
In numerous sport and occupational settings, individuals often need to perform multiple exercise sessions in one day or across consecutive days, yet performance and perceptual responses to such exercise paradigms are unclear. PURPOSE: This study investigated performance fatigue and perceptual responses to repeated, consecutive sessions of high-intensity interval (HIIT) and constant-work rate (CWR) cycling bouts performed within 24 hours.

Methods
Seventeen healthy adults (nine females, aged 25 ± 6 years) exercised in the morning, same afternoon, and following morning. Sessions consisted of work- and duration-matched HIIT (2 min at 80% peak power output (PPO) interspersed by 2 min at 25% PPO) and CWR cycling (38 min at 54% PPO). A time-to-task failure (TTF) trial at 80% PPO was completed followed both morning sessions. Neuromuscular assessments, including isometric knee extension maximal voluntary contraction (MVC) coupled with superimposed and potentiated (Qtw) twitches, elicited via electrical stimuli to the femoral nerve, were performed before and after workouts, and after the TTF. Blood lactate and perceptual responses were also measured.

Results
TTF trials were longer following CWR than HIIT (P < 0.001). Across consecutive sessions, voluntary activation remained depressed, and this was accompanied by progressive impairments in cycling TTF following CWR (P = 0.006). Conversely, MVC and Qtw returned to baseline values by the beginning of each HIIT and CWR session. Perceived effort and dyspnea were higher in HIIT but were not exacerbated across sessions.

Conclusions
While declined voluntary and evoked force-generating capacities did not persist in this study, consecutive exercise could compromise the recovery of voluntary activation and endurance performance.
The Link Between Gut Microbiota and Depression: Exploring the Correlation
Authors: Juśkiewicz Adam , Grelewicz Olga , Kucy Natalia , Servaas Elwira , Haber Mateusz , Kula Paula , Czachor Adrianna , Kotula Alicja 
Published: February 2025

Introduction: Depression represents a significant global health challenge, affecting approximately 4.4% of the global population and ranking as the leading cause of disability worldwide. Despite advancements in pharmacotherapy and psychotherapeutic interventions, a substantial proportion of individuals with depression experience treatment resistance, recurrence of symptoms, or inadequate response to standard treatments.

Aim of the Study: This review explores the emerging role of the gut microbiome in depression, focusing on its potential as a therapeutic target.

Materials and Methods: A comprehensive literature search was conducted using electronic databases including PubMed/MEDLINE and Google Scholar. The search encompassed articles utilizing keywords and Medical Subject Headings (MeSH) terms related to “gut microbiome,” “depression,” “microbiota-gut-brain axis,” “psychiatric disorders,” and “clinical studies.”

Conclusion: Therapeutic strategies targeting the gut microbiota offer promising avenues for alleviating depressive symptoms and enhancing treatment outcomes. Probiotics, prebiotics, dietary modifications, and fecal microbiota transplantation (FMT) represent diverse interventions aimed at restoring microbial balance, modulating gut-brain communication, and reducing neuroinflammation associated with depression. Further research is needed to optimize therapeutic approaches, explore personalized medicine strategies based on individual microbiome profiles and clarify the safety and efficacy of microbial-based therapies in clinical settings.
Urasowienie narodu i przenarodowienie rasy, czyli o dwukierunkowej transformacji w polskiej refleksji romantycznej
Authors: Nowak Joanna 
Published: February 2025

Celem artykułu jest rekonstrukcja dwukierunkowego procesu transformacji pojęciowej narodu w rasę i rasy w naród na wybranych tekstach polskich autorów, piszących w epoce międzypowstaniowej, w której proces urasowienia narodu został zainicjowany przez polskie elity polityczno-intelektualne w określonym celu. Był to okres dominacji formacji romantycznej, w której kategoria narodu zdominowała dyskurs dotyczący podziałów w świecie ludzkim w tym także pojęcie „rasy” sprowadzonej do roli grupy narodowej lub etnicznej o trwałych cechach. Urasowienie narodu w pozanaukowym przekazie następowało przez nałożenie na wzorzec kulturowy wspólnoty cech uznanych za typowe dla opisywanej rasy.
The Role of Lifestyle in the Prevention and Treatment of Insulin Resistance: A Review of Clinical and Intervention Studies
Authors: Rybak Daria , Krupa Olga , Furtak Kinga , Wójcik Zofia Martyna , Romańczuk Kuba Borys , Stolarczyk Szymon Przemysław , Pietrukaniec Paulina Dorota , Omasta Bartosz , Kamińska-Omasta Katarzyna , Czerska Magdalena Agata 
Published: February 2025

Introduction
Insulin resistance (IR) is a metabolic disorder characterized by reduced tissue sensitivity to insulin, resulting in impaired glucose homeostasis. IR plays a pivotal role in the development of type 2 diabetes, metabolic syndrome, and associated cardiovascular complications. Effective strategies for the prevention and treatment of IR focus on lifestyle modification, including physical activity and stress management.
Aim of the Study
The aim of this study is to evaluate the role of lifestyle factors in the prevention and treatment of insulin resistance (IR) based on the analysis of clinical and interventional studies, with a particular focus on dietary interventions, physical activity programs, stress reduction techniques, and sleep quality improvement recommendations.
Materials and Methods
A review of clinical and interventional studies was conducted using databases such as PubMed. The analysis included studies evaluating the impact of specific lifestyle interventions on markers of insulin resistance (IR), such as fasting insulin levels, HOMA-IR indices and glucose tolerance. Particular attention was paid to randomized controlled trials (RCTs) and meta-analyses published between 2020 and 2024.
Summary
Studies have shown that diets such as the Mediterranean and DASH, combined with regular aerobic and resistance exercises, significantly improve insulin sensitivity. Additionally, stress-reduction techniques like mindfulness and yoga, along with adequate sleep quality, enhance positive metabolic effects. These findings highlight the need for a multifaceted approach to treating insulin resistance, incorporating dietary and behavioral changes. The review also points out research gaps and emphasizes the necessity of long-term studies to refine lifestyle recommendations for diverse populations
Microanalysis of minerals in Rhizophora mangle L. leaves from Marambaia mangroves reveal low presence of potentially toxic elements
Authors: Torres Alves Guilherme , Do Carmo de Oliveira Arruda Rosani , Pimentel Victório Cristiane 
Published: February 2025

The mangroves of Marambaia, area bathed by the Bay of Sepetiba, is located in an area protected by the Brazilian Army and has a remarkable level of environmental protection among ecosystems around the bay. Leaf content of minerals and potentially toxic elements in a typical species of mangrove of Rhizophora mangle L. were analyzed from samples collected in Marambaia. Microanalyses of minerals were done by Energy Dispersive X-Ray Spectroscopy coupled to Scanning Electron Microscope (EDX-SEM) that showed the elemental composition and its relative quantity in R. mangle leaves. The major mineral deteced were Na, Ca and Cl, and low concentration of Zn.
Diagnostic, prognostic, and therapeutic potentials of gut microbiome profiling in human schistosomiasis: A comprehensive systematic review
Authors: Oyono Martin Gael , Kenmoe Sebastien , Ebogo Belobo Jean Thierry , Mbah Ntepe Leonel Javeres , Kameni Mireille , Kamguia Leonel Meyo , Mpotje Thabo , Nono Justin Komguep 
Published: February 2025

Background
Several studies have highlighted alteration in the gut microbiome associated with the onset and progression of diseases. Recognizing the potential of gut microbiota as biomarkers, this systematic review seeks to synthesize current data on the intricate relationship between the host gut microbiome profiles and their usefulness for the development of diagnostic, prognostic and therapeutic approaches to control human schistosomiasis.

Methods
A systematic literature review was carried out by searching for relevant studies published until date, that is May 2024, using Medline, Embase, Global Health, Web of Science, and Global Index Medicus databases. The keywords used to select articles were "Gut microbiome", "Gut Microbiota", "Schistosomiasis", "Bilharziasis ", and "Human". Extracted data were analysed qualitatively from the selected articles.

Results
Of the 885 articles retrieved and screened, only 13 (1.47%) met the inclusion criteria and were included in this review. Of the included studies, 6 (46.2%) explored alterations of gut microbiome in schistosome-infected patients, 4 (30.7%) in patients with liver pathologies, and 3 (23.1%) in patients treated with praziquantel. Bacteria from the genera Bacteroides, Faecalibacterium, Blautia and Megasphaera were associated with S. japonicum and S. haematobium infection in school-aged children, whereas infection with S. mansoni rather associated with Klebsiella and Enterobacter. The gut microbiota signature in patient with schistosomiasis-induced liver pathology was reported only for S. japonicum, and the genus Prevotella appeared as a non-invasive biomarker of S. japonicum-associated liver fibrosis. For S. mansoni-infected school-aged children, it further appeared that the treatment outcome following praziquantel administration associated with the abundance in the gut microbiome of bacteria from the classes Fusobacteriales, Rickettsiales and Neisseriales.

Conclusion
The host gut microbiome appears to be a valuable, non-invasive, but still poorly utilized, source of host biomarkers potentially informative for better diagnosing, prognosing and treating schistosomiasis. Further studies are therefore needed to comprehensively define such gut microbial biomarkers of human schistosomiasis and catalyse the informed development of gut microbiome-based tools of schistosomiasis control.
Unique North American isolates of severe metastatic hypervirulent Klebsiella pneumoniae strain infections with hepatic abscesses seen in young patients within Texas
Authors: Alam Junaid M. , Riha Eric N. , Ahmed Haris , Thai Hong M. , Garnepudi Kevin , Kesavan Ramesh B. , Jayaraman Gnananandh , Sangster Anna , Curry Dylan , Butz Heidi A. , Smith Lori , Vowles Maureen , Oakeson Kelly F. , Young Erin L. , Sarva Siva T. 
Published: February 2025

Rationale
Hypervirulent Klebsiella pneumoniae (hvKp) infections have principally been identified in Asia. Within a two-month period, two patients between the ages of 30 to 50 years old presented to a tertiary referral hospital in Texas with septic shock, hepatic abscess, and septic thrombophlebitis. Blood cultures were positive for Klebsiella pneumoniae (isolates 2020CK-00441 and 2021CK-00720 respectively). The first patient survived after a prolonged hospital course while the second patient expired.

Objectives
Describe the clinical presentation of these two patients. Perform whole genome sequencing and bioinformatic analysis to evaluate potential outbreak of specific hvKp bacteria isolates.

Methods
Whole genome sequencing was performed using both paired-end Illumina MiSeq and nanopore sequencing to obtain a Completed genome for both isolates.

Main results
2020CK-00441 belonged to ST23 type while 2021CK-00720 was a ST65 type isolate. Kleborate analyses predicted with high confidence both isolates were hvKp. Phylogenetic analyses showed the two strains are not closely related to each other nor to any known hvKp isolates reported. Both isolates had yersiniabactin, colibactin, aerobactin and salmochelin producing loci which likely confer these isolates hvKp phenotype. 2020CK-00441 and 2021CK-00720 had a unique pK2044 like plasmid.

Conclusions
HvKp strains capable of causing devastating metastatic septic infections have emerged in Texas. These isolates are unique compared to other hvKp strains globally. Country-wide surveillance and whole genome sequencing of these strains is essential to prevent a major public health emergency in the USA.
Utilizing MV-FLOW™ and multidimensional ultrasound characteristics for prognosticating FET outcomes in RIF patients: Study Protocol for a cross-sectional study
Authors: Zhou Ying , Liu Li-Ying , Yang Hua-Ju , Lai Yuan-Yuan , Gan Di , Yang Jie 
Published: February 2025

Recurrent implantation failure (RIF) is a common issue in frozen-thawed embryo transfer (FET). Prior to transfer, uterine endometrial receptivity of FET patients can be assessed using multimodal transvaginal ultrasound indicators to predict the success rate of the current FET cycle. Endometrial blood flow is a crucial element in evaluating endometrial receptivity. MV-FLOW™ is an advanced two-dimensional superb microvascular imaging technology that can detect and display blood flow in micro-vessels. The data for this study were obtained from an ongoing cross-sectional study comprising 323 RIF patients and 323 first implantation (FI) patients, who underwent transvaginal ultrasound before FET. We collected basic clinical data and multimodal ultrasound data from these patients as predictive features, with clinical pregnancy as the predictive label, for model training. Based on the above, this study aims to establish and validate a clinical prediction model for FET outcomes using support vector classification (SVC) algorithms, based on MV-FLOW™ and multidimensional transvaginal ultrasound imaging features. The objective is to determine the predictive role of multimodal transvaginal ultrasound in embryo transfer outcomes and provide evidence for the clinical application of MV-FLOW™.
Trial registration: Trial Registration: ChiCTR2400086401.