bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetohydrodynamical Torsional Oscillations from Thermoresistive Instability in Hot Jupiters
Authors: Hardy Raphaël , Charbonneau Paul , Cumming Andrew 
Published: December 2023

Abstract
Hot Jupiter atmospheres may be subject to a thermoresistive instability where an increase in the electrical conductivity due to ohmic heating results in runaway of the atmospheric temperature. We introduce a simplified one-dimensional model of the equatorial substellar region of a hot Jupiter that includes the temperature dependence and time dependence of the electrical conductivity, as well as the dynamical back-reaction of the magnetic field on the flow. This model extends our previous one-zone model to include the radial structure of the atmosphere. Spatial gradients of electrical conductivity strongly modify the radial profile of Alfvénic oscillations, leading to steepening and downward transport of magnetic field, enhancing dissipation at depth. We find unstable solutions that lead to self-sustained oscillations for equilibrium temperatures in the range T
eq ≈ 1000–1200 K and radial magnetic field strength in the range ≈10–100 G. For a given set of parameters, self-sustained oscillations occur in a narrow range of equilibrium temperatures that allow the magnetic Reynolds number to alternate between large and small values during an oscillation cycle. With our simplified geometry, outside of this temperature window the system reaches a steady state in which the effect of the magnetic field can be approximated as a magnetic drag term. Our results show that thermoresistive instability is a possible source of variability in magnetized hot Jupiters at colder temperatures and emphasize the importance of including the temperature dependence of electrical conductivity in models of atmospheric dynamics.
A Jupyter notebook to explore protein conformations: An output of PaNOSC SP8 case
Authors: Safiulina Irina , Gonzalez Miguel Angel , Mutti Paolo , La Rocca Giuseppe , Fernández Enol 
Published: December 2023

Small-angle scattering techniques are widely employed across scientific communities to elucidate the morphology, spatial distribution, and uniformity of particles within liquid solutions. Recent advancements and accelerated data acquisition capabilities have extended the utility of these techniques to probe the dynamic behavior of particles over time. Small-Angle X-ray Scattering (SAXS) and Small-Angle Neutron Scattering (SANS) emerge as powerful tools in this realm, enabling the investigation of phenomena such as the time-dependent release of genomes from phages, the comprehensive exploration of viral life cycles, and the assembly dynamics of macromolecular complexes. This tandem application of X-rays and neutrons, exemplified by the collaborative SANS-SAXS initiative between the European Synchrotron Radiation Facility (ESRF) and the Institut Laue-Langevin (ILL), yields complementary insights into complex infection pathways.
In this report, we present the outcomes of a software development project undertaken as part of Science Project 8: "PaNOSC Dynamics of Biological Processes" within the EOSC Future framework. The project's deliverables include a Jupyter Notebook and accompanying Python scripts, specifically sas_helper.py. The primary objective of Science Project 8 is to expand the accessibility of open Small-Angle Neutron Scattering (SANS) and Small-Angle X-ray Scattering (SAXS) data to a broader scientific community. This endeavor underscores the profound transformative potential of open-science data analysis within the European Open Science Cloud (EOSC) framework while advocating for the adoption of FAIR (Findable, Accessible, Interoperable, and Reusable) principles in scientific research.
Diversity of parasitoid wasps (Insecta, Hymenoptera) in oilseed rape fields in Serbia
Authors: Plećaš Milan , Žikić Vladimir , Kocić Korana , Čkrkić Jelisaveta , Petrović Anđeljko , Tomanović Željko 
Published: December 2023

Oilseed rape is an important crop grown worldwide and used for various purposes, including oil extraction and animal feed. In Europe, there are six major pest species and several other minor pests that can significantly affect oilseed rape production, requiring growers to effectively control them in order to ensure crop yield. The host-parasitoid complexes of these pests have been studied in detail and recorded mainly in western, central and northern Europe. As an abundant source of pollen and nectar, oilseed rape may also be attractive to other parasitoids that do not have direct trophic interactions with oilseed rape pest species. The aim of this study is to fill the knowledge gap regarding the wider parasitoid community in oilseed rape fields, particularly in southern Europe.
During the two-year study, a total of 3135 specimens of primary and secondary parasitoids were sampled, of which 2855 were found in oilseed rape fields and 280 in semi-natural habitats. We found 153 taxa, of which 119 were found in oilseed rape fields and 87 in semi-natural habitats. We identified 31 genera (33 species) as parasitoids of oilseed rape pests, 54 genera (97 species) parasitising non-pest species and 10 genera (23 species) as possible parasitoids of oilseed rape pests. This study shows that the parasitoid community in oilseed rape fields is very diverse and that includes parasitoids of both oilseed rape pest and non-pest species.
La technologie comme principe de destruction écologique
Authors: Autard Jean 
Published: December 2023

Quoique la technologie joue un rôle prépondérant dans les désastres écologiques en cours, son rôle a souvent été minoré au profit de déterminants sociaux, idéologiques voire biologiques supposément plus primordiaux. Au contraire, il s’agit de montrer que la technologie est porteuse d’une tendance propre, d’un effet émergent qui empêcherait de la réorienter complètement pour produire une technologie (appuyée sur la science et l’ingénierie et optimisée rationnellement) compatible avec l’écologie. En particulier, la voie des « technologies vertes » telles qu’illustrée par le domaine des énergies renouvelables apparaît comme une impasse contreproductive, tandis que l’emprise de sciences naturelles gestionnaires sur la définition des enjeux de l’écologie produit une puissante dépolitisation et naturalisation de ces questions. Ajouter aux critiques du capitalisme ou de l’anthropocentrisme une approche technocritique est donc une nécessité.
Adaptation des petits et moyens agriculteurs aux enjeux environnementaux
Authors: Bruis-Gervasone Lucie 
Published: December 2023

Nous étudions comment l’adaptation aux enjeux environnementaux des petits et moyens agriculteurs, cœur de la profession agricole, participe de manière décisive aux transformations agricoles actuelles. À partir d’une enquête menée en région Provence-Alpes-Côte d’Azur, nous montrons que cette adaptation a pour fondement une évolution de l’ ethos d’une partie des membres de cette fraction de classe. Nous observons notamment chez les agriculteurs rencontrés une importance croissante accordée aux activités gestionnaires et commerciales, ainsi qu’une plus grande collaboration entre pairs. Ces composantes s’inscrivent dans le sillage d’une aspiration toujours très forte à l’autonomie. Nous formulons l’hypothèse que s’ouvre dans la décennie 2010 une nouvelle période dans le processus d’évolution environnementale de l’agriculture marquée par une recomposition de la contradiction économie/environnement, contradiction apparue avec le développement des premières mesures agro-environnementales de la politique agricole commune (PAC) au début des années 1990.
Perception and Recognition of Clinical Medical Physicist Roles and Responsibilities by Specialist Physician Staff: The First Mexican Survey
Authors: Bojórquez Mariana Hernández , Rendón Xóchitl López , Rojas-López José Alejandro 
Published: December 2023

Introduction:
Although medical physics as a profession is recognized as part of the health-care professional workforce by the International Labor Organization, in the Mexican context, the figure of the medical physicist (MP) is often inappropriately associated solely with technical work, leading to perception, recognition, and salary implications. The aim of this study was to explore the perception of medical specialists regarding the role and responsibilities of MPs in clinical practice in Mexico.

Methods:
A national survey was answered by medical personnel, ranging from residents to qualified specialists in November 2019. The questionnaire consisted of ten questions related to perception of MPs. The survey was open to all medical specialists regardless of their involvement in the use of ionizing radiations or otherwise.

Results:
It was shown that approximately two-thirds of specialists know and recognize the medical physics profession in hospitals and the roles and responsibilities of MPs. However, 19% of medical specialists considered the standard of service as inadequate.

Conclusion:
MPs must exert greater efforts to promote their status and enhance the recognition of their contribution to health care. The low level of recognition in diagnostic and interventional radiology and in nuclear medicine in Mexico might be related to nonexistent or unclear documentation and inadequate regulations, policies, or directives promoted by the health-care authorities.
Gastrointestinal Manifestations of Chagas Disease: A Systematic Review with Meta-Analysis
Authors: Baldoni Nayara Ragi , de Oliveira-da Silva Lea Campos , Gonçalves Ana Carolina Oliveira , Quintino Nayara Dornela , Ferreira Ariela Mota , Bierrenbach Ana Luiza , Padilha da Silva José Luiz , Pereira Nunes Maria Carmo , Ribeiro Antonio Luiz P. , Oliveira Claudia Di Lorenzo , Sabino Ester Cerdeira , Cardoso Clareci Silva 
Published: December 2023

ABSTRACT.
The aims of this study were to estimate the prevalence of gastrointestinal manifestations among individuals with positive serology for Chagas disease (ChD) and to describe the clinical gastrointestinal manifestations of the disease. A systematic review with meta-analysis was conducted based on the criteria and recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. The PubMed, Scopus, Virtual Health Library, Web of Science, and Embase databases were used to search for evidence. Two reviewers independently selected eligible articles and extracted data. RStudio® software was used for the meta-analysis. For subgroup analysis, the studies were divided according to the origin of the individuals included: 1) individuals from health units were included in the health care service prevalence analysis, and 2) individuals from the general population were included in the population prevalence analysis. A total of 2,570 articles were identified, but after removal of duplicates and application of inclusion criteria, 24 articles were included and 21 were part of the meta-analysis. Most of the studies were conducted in Brazil. Radiological diagnosis was the most frequent method used to identify the gastrointestinal clinical form. The combined effect of meta-analysis studies showed a prevalence of gastrointestinal manifestations in individuals with ChD of 12% (95% CI, 8.0–17.0%). In subgroup analysis, the prevalence for studies involving health care services was 16% (95% CI, 11.0–23.0%), while the prevalence for population-based studies was 9% (95% CI, 5.0–15.0%). Megaesophagus and megacolon were the main forms of ChD presentation in the gastrointestinal form. The prevalence of gastrointestinal manifestations of ChD was 12%. Knowing the prevalence of ChD in its gastrointestinal form is an important step in planning health actions for these patients.
GCSB-5 regulates inflammatory arthritis and pain by modulating the mitogen-activated protein kinase signaling pathway in a murine model of rheumatoid arthritis
Authors: Bang Jihye , Kim Gyeonghwa , Young Park Soo , Jung Hye Ra , Kim Sang-Hyon , Kim Ji-Min 
Published: December 2023

Objectives: This study aimed to determine whether GCSB-5 has anti-inflammatory and antinociceptive effects in mice with collagen-induced arthritis (CIA), an animal model of rheumatoid arthritis (RA), and investigate the influence of GCSB-5 on the mitogen-activated protein kinase (MAPK) pathway.
Materials and methods: The experimental animal study was designed to include five groups: CIA mice treated with GCSB-5 (300 mg/kg), GCSB-5 (600 mg/kg), celecoxib (60 mg/kg), or saline for four weeks, and nontreated control mice. The clinical severity of arthritis was scored. Nociceptive thresholds were measured by using a von Frey dynamic plantar analgesimeter. The MAPK pathway was evaluated in mouse synovium. The expression of channels associated with pain signaling was assessed by western blot and immunohistochemical staining.
Results: GCSB-5 treatment diminished the severity of clinical arthritis and increased the nociceptive threshold in mice with CIA. Celecoxib, a positive control drug, also showed comparable changes. Clinical arthritis scores were inversely related to mechanical thresholds. GCSB-5 administration decreased the levels of anti-type II collagen antibody and inflammatory cytokines in the sera of mice with CIA. Furthermore, ERK, p38 MAPK, and JNK phosphorylation were downregulated and TRPV1 and ASIC3 expression were decreased in the synovium of GCSB-5-treated mice compared to salinetreated mice. Interleukin-6-induced TRPV1 and ASIC3 upregulation were also inhibited by GCSB-5 in human RA fibroblast-like synoviocytes in vitro.
Conclusion: GCSB-5 decreased inflammatory arthritis and pain in a murine model of RA. The results present evidence that GCSB-5 may be beneficial for relieving pain as well as decreasing inflammation in autoimmune arthritis, such as RA.
Does age at disease onset affect the clinical presentation and outcome in children with immunoglobulin A vasculitis?
Authors: Nur Sunar Yayla Emine , Bakkaloğlu Sevcan A. 
Published: December 2023

Objectives: The study aimed to determine whether there is a relationship between the age at diagnosis and the clinical, laboratory, and prognostic features in pediatric immunoglobulin A vasculitis (IgAV) patients.
Patients and methods: In this study, 539 pediatric IgAV patients (298 males, 241 females; mean age: 7.74±3.36 years; range, 1 to 17.8 years) were retrospectively evaluated between January 2005 and July 2020. The relationship between clinical findings and age at diagnosis was analyzed by univariate logistic regression analysis. Factors associated with renal involvement, steroid-dependent or refractory disease, and recurrence were examined.
Results: The median age of diagnosis was 7.1 (1-17.8) years in all patients. At the time of admission, purpura, abdominal pain, and arthritis were the most common clinical findings. At the time of diagnosis, there was a positive association between age and purpura and an inverse association with the presence of arthritis. There were associations between renal involvement and age at diagnosis (odds ratio=1.22, 95% confidence interval 1.13-1.31, p<0.001), follow-up time (p<0.001), no history of previous infection (p<0.001), and presence of gastrointestinal (GI) involvement (p=0.003). Significant relationships were found between the age at diagnosis, follow-up time, GI involvement, renal involvement, scrotal involvement, the C-reactive protein value at the time of diagnosis, and the presence of steroid-dependent disease. An association was found between recurrence and GI involvement. All refractory patients had renal involvement. Age at diagnosis (p<0.001) and follow-up time (p<0.001) was found to be associated with refractory disease.
Conclusion: Age at diagnosis and follow-up time may be associated with renal involvement and refractory and steroid-dependent disease in IgAV. In addition, there may be a relationship between steroid-dependent disease and renal, GI, and scrotal involvement and between GI involvement and recurrence.
The short-term effect of glucosamine-sulfate, nonanimal chondroitin-sulfate, and S-adenosylmethionine combination on ultrasonography findings, inflammation, pain, and functionality in patients with knee osteoarthritis: A pilot, double-blind, randomized, placebo-controlled clinical trial
Authors: Veličković1† Zoran , Pavlov Dolijanović Slavica , Stojanović Nikola , Janjić Saša , Kovačević Ljiljana , Soldatović Ivan , Radunović Goran 
Published: December 2023

Objectives: This study aimed to investigate the efficacy of glucosamine-sulfate (GS), nonanimal chondroitin-sulfate (naCS), and S-adenosylmethionine (SAMe) combination on ultrasound findings, inflammation, pain, and functionality in knee osteoarthritis.
Patients and methods: In the prospective, randomized, double-blind, placebo-controlled pilot study conducted between August 2019 and November 2019, 120 participants (28 males, 92 females; mean age: 66.4±7.9 years; range, 42.4 to 74.5 years) were randomized at a 1:1:1 ratio to the placebo group, the first experimental group (a combination of GS, naCS, and SAMe was administered to the experimental groups. The first experimental group received 375 mg of GS, 300 mg of naCS, and 100 mg of SAMe, whereas the second experimental group received 750 mg of GS, 600 mg of naCS, and 200 mg of SAMe). Laboratory (erythrocyte sedimentation rate, C-reactive protein, tumor necrosis factor alpha, interleukin [IL]-1β, IL-6, IL-17), clinical (Visual Analog Scale [VAS], short form health survey [SF-36], the Western Ontario and McMaster Universities Arthritis Index [WOMAC], and the Tegner Lysholm Knee Scoring Scale [TLKS]), and musculoskeletal ultrasound (MSUS) assessments were performed at baseline and after three and six months.
Results: A minor increase was observed in the second experimental group after six months using ultrasonography to evaluate articular cartilage thickness (p<0.05). The investigational product's superiority in reducing osteoarthritis ultrasonographic findings was not proven. A moderately negative association was found between cartilage thickness and VAS scores at baseline (ρ=-0.36, p<0.01), while the presence of massive osteophytes on MSUS showed a low to moderate association with all clinical outcomes. There was no difference in the delta changes between groups for the VAS, TLKS, WOMAC, and SF-36. The only serum inflammatory marker outside the reference range was IL-1β, but no significant changes were observed after six months.
Conclusion: According to the results of our investigation, treatment for knee osteoarthritis should be evaluated using more objective outcomes. The most important conclusion of our study is that IP may result in a slight increase in articular cartilage thickness, which was associated with a decrease in pain intensity at baseline. Clarification of the potential influence of this combination on radiographic progression and laboratory markers of inflammation requires further exploration.
Test–Retest Reliability of the Electronic Instrumental activities of daily living Satisfaction Assessment (EISA): A Cohort Study
Authors: Quamar Abbas H. , Schmeler Mark R. , McCue Michael , Cooper Rory A. , Goldberg Mary R. , DiGiovine Carmen , Collins Diane M. , Schein Richard M. 
Published: December 2023

Abstract
Importance: Currently, no self-report instruments exist for assessing satisfaction with performing instrumental activities of daily living and occupations for people with disabilities using internet-connected assistive devices like accessible smartphones, tablets, laptops, and apps.
Objective: To assess the test–retest reliability and internal consistency of the Electronic Instrumental activities of daily living Satisfaction Assessment (EISA) self-report outcome tool.
Design: Repeated-measures cohort study with a time frame of 7 to 21 days.
Setting: Multicity online recruitment at assistive technology clinics, nongovernmental organizations, advocacy and peer support groups for people with disabilities, and higher education institutions.
Participants: Eighty-four participants with disabilities, age 18 yr or older, with a mean age of 43.3 yr (range = 19–75 yr), and 57% female.
Intervention: Not applicable.
Outcomes and Measures: The a priori study hypotheses were that the EISA test–retest reliability scores would be above the minimum acceptable level (Rs &gt; .80) and that internal consistency would be good (Cronbach’s α = .70–.90).
Results: On the basis of the study data, the EISA, Version 1.0, demonstrated good test–retest reliability (Rs = .81) and excellent internal consistency (Cronbach’s α = .88).
Conclusions and Relevance: The results of the test–retest reliability and internal consistency analyses provide good support for the EISA to be used in clinical settings.
What This Article Adds: This article documents the reliability and internal consistency of, to our knowledge, the first-ever self-report instrument for assessing satisfaction with performance of everyday occupations for people with disabilities using internet-connected assistive devices such as smartphones, tablets, laptops, and apps.
UMA REFLEXÃO ACERCA DA EFETIVIDADE DA LEI MARIA DA PENHA NO COMBATE À VIOLÊNCIA DOMÉSTICA E FAMILIAR CONTRA A MULHER: REPENSANDO A LEI À LUZ DO PRINCÍPIO CONSTITUCIONAL DA IGUALDADE
Authors: Carvalho Sarah Leandra Garcia de , Medeiros Beatriz Helenice Evangelista 
Published: December 2023

A Lei 11.340/06, amplamente conhecida como Lei Maria da Penha, tem como objetivo criar mecanismos para coibir a violência doméstica e familiar contra as mulheres, bem como estabelecer medidas de assistência e proteção às vítimas. Concomitantemente, dá cumprimento às convenções internacionais que o país ratificou, destinadas a combater esse tipo de violação. Contudo, no contexto legal brasileiro, a referida norma tem enfrentado desafios relacionados à sua constitucionalidade em relação ao princípio da igualdade consagrado na Constituição Federal. Alguns argumentam que a lei poderia ser vista como inconstitucional sob a ótica da igualdade de gênero, uma vez que ela estabelece medidas especiais de proteção para as mulheres vítimas de violência doméstica, enquanto os homens não recebem tratamento semelhante em casos de violência. Todavia, a maior parte da jurisprudência e dos debates jurídicos no Brasil sustenta que a Lei Maria da Penha é constitucional, baseada em argumentos de que ela se justifica pela necessidade de combater uma forma específica de violência historicamente direcionada às mulheres. Essa justificativa leva em consideração a chamada "discriminação positiva" ou "ação afirmativa", que visa corrigir desigualdades históricas e estruturais entre gêneros. Nesse sentido, o Supremo Tribunal Federal (STF) do Brasil tem se manifestado a favor da constitucionalidade da Lei Maria da Penha em várias ocasiões. Inclusive, a Ação Declaratória de Constitucionalidade n° 19 (ADC/19), entendeu que a Lei 11.340/06 não viola o princípio da igualdade, porquanto se trata de uma ação positiva, que visa corrigir as injustiças que as mulheres têm sofrido ao longo do tempo. Diante disso, a lei continua em vigor como um instrumento fundamental para combater a violência de gênero no país, equilibrando o princípio da igualdade com medidas específicas para proteger as mulheres em situações de violência doméstica.