bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antioxidant and antimicrobial effect of sodium alginate nanoemulsion coating enriched with oregano essential oil (Origanum vulgare L.) and Trachyspermum ammi oil (Carum cupticum) on food pathogenic bacteria
Authors: Saffarian Hashem , Rahimi Ebrahim , Khamesipour Faham , Hashemi Dehkordi Seyed Majid 
Published: February 2024

AbstractToday, microbial contamination in food is one of the major problems of the food industry and public health in general around the world. Foodborne illnesses, such as diarrheal diseases, kill many people around the world each year. The general objective of this study was to evaluate the antioxidant and antibacterial activity of sodium alginate nanoemulsion coating incorporated with oregano essential oil (Origanum vulgare L.) and Trachyspermum ammi oil (Carum cupticum) on Escherichia coli, and Listeria monocytogenes. To achieve this study, fresh chicken meat was used for this experiment. Listeria monocytogenes ATCC 19111 and Escherichia coli ATCC 35218 were obtained from the American Type Culture Collection (Manassas, VA, USA). After the preparation of the essential oil, the chemical composition of this essential oil was determined by using (GC–MS). The physicochemical properties of the nanoemulsion essential oil prepared were characterized and their antimicrobial activity was evaluated. The results showed that the GC–MS analysis of the volatile constituents of the Origanum vulgare essential oil compounds allowed the identification of 19 compounds representing 93.72% of the total oil. The major components detected in Origanum vulgare essential oil were pulegone (49.25%), eucalyptol (18.23%), and menthone (12.37%). About the Carum cupticum essential oil, 21 compounds representing 98.5% of the total oil were identified. The major components detected in Origanum vulgare essential oil were thymol (23.3%), p‐cymene (17.5%), and γ‐terpinene (16.8%). The best z‐average (d.nm) is 483.4 nm (Carum cupticum essential oil + nano) followed by 470.1 nm (nanochitosan). The results of the antimicrobial test showed that the different preparations have a good inhibitory activity for the in vitro growth of Escherichia coli and Listeria monocytogenes. According to the MIC and MBC results of this study, the nanoemulsion also presented a good bacteriostatic activity against the two pathogenic bacteria tested in this study.
Factors affecting purchase intention of organic food products: Evidence from a developing nation context
Authors: Bazhan Marjan , Shafiei Sabet Farnam , Borumandnia Nasrin 
Published: February 2024

AbstractThe organic food industry has experienced rapid growth in recent decades. The industry is relatively new to developing countries compared to developed countries. Since Iran has the potential to produce organic products, it is essential to study factors that influence consumers' intention to buy them. The present study was designed and implemented for this purpose. In this cross‐sectional study, 520 adults were selected using multistage sampling. Path analysis was employed to test a hypothesized model of predictors of consumer purchase intention for organic food. Attitude, environmental concern, and sensory characteristics directly impacted the intention to purchase organic food (p < .01). Knowledge, perceived price, and household size indirectly affected purchase intention through attitude (p < .01). Age indirectly affected purchase intention through health consciousness, environmental concern, perceived price, and sensory characteristics (p < .01). Subjective norms, health consciousness, and the perceived convenience of purchase had a positive and significant effect on purchase intention, directly and indirectly, through the mediating influence of attitude (p = .000). The educational level also affects purchase intention directly and indirectly through knowledge, health consciousness, environmental concern, and subjective norm (p = .000). The most potent total effects belonged to health consciousness, subjective norms, and education, respectively. Overall, the model could explain 47% of the intention variance and 45% of the variance in attitude. Various factors influence Iranian consumers' decision to buy organic food. This information can help professionals make well‐informed decisions in policymaking, production, marketing, tourism, and retailing.
Investigation of the simulated microgravity impact on heavy metal biosorption by Saccharomyces cerevisiae
Authors: Salavatifar Maryam , Khosravi‐Darani Kianoush 
Published: February 2024

AbstractHeavy metals are one of the most dangerous environmental pollutions, and their elimination is one of the health system's priorities. Microorganisms have been introduced as a safe absorber of such pollution and this ability is related to the characteristics of their surface layers. There are reports about some bacteria's increment of cell envelope thickness in space conditions. Therefore, this study investigated SMG effect on heavy metals biosorption using Saccharomyces (S.) cerevisiae. Furthermore, the stability of complex, isotherm, and kinetic absorption models has been investigated. The results showed that the SMG positively affected the biosorption of mercury (Hg) 97% and lead (Pb) 72.5% by S. cerevisiae. In contrast, it did not affect cadmium (Cd) and arsenic (As) biosorption. In gastrointestinal conditions, Hg, Cd, and As‐yeast complexes were stable, and their biosorption increased. In the case of the Pb‐yeast complex, in simulated gastric exposure, the binding decreased at first but increased again in simulated intestinal exposure in both SMG and normal gravity (NG). The metals' biosorption by yeast followed the pseudo‐second‐order kinetic and the Langmuir isotherm models for all metals (As) matched with Langmuir and Freundlich. The current research results demonstrate that microgravity provides desirable conditions for heavy metal biosorption by S. cerevisiae. Furthermore, the biosorbent–heavy metal complex remains stable after simulated gastrointestinal conditions. Altogether, the results of this study could be considered in detoxifying food and beverage industries and maintaining astronauts' health.
Effect of waiting time for radiotherapy after last induction chemotherapy on prognosis of locally advanced nasopharyngeal carcinoma
Authors: Zhu Kui‐Xuan , Ding Ting , E Yi‐Min , Yang Hong‐Wei , Wu Rui‐Ping , Liu Run‐Jia , Zhou Ling‐Li , Fu Wen‐Jie , Jiang Mei‐Ping , Wang Xiao‐Li 
Published: February 2024

AbstractBackgroundThe effect of radiotherapy waiting time after last induction chemotherapy (IC‐RT) on prognosis of patients with locally advanced nasopharyngeal carcinoma (LANPC) needs further discussion.MethodsThree hundred and six patients with LANPC diagnosed pathologically by induction chemotherapy (IC) and radiotherapy (RT) from 2013 to 2018 were selected for this study.ResultsThe IC‐RT was a risk factor for the post‐treatment progression of LANPC (OR = 1.017 95%CI: 1.003–1.031), For patients with LANPC, the IC‐RT > 40 days significantly reduced 5‐year PFS (70% vs. 55%; p = 0.0012), 5‐year OS (84% vs. 73%; p = 0.028), 5‐year DMFS (80% vs. 66%; p = 0.003), 5‐year LRFS (77% vs. 67%; p = 0.012). Indicating that patients with stage IVa who IC‐RT > 40 days were found to be a significant predictor of aggravated PFS (HR = 2.69; 95%CI: 1.57–4.6), OS (HR = 2.55; 95%CI: 1.29–5.03), DMFS (HR = 3.07; 95%CI: 1.64–5.76) and LRFS (HR = 2.26; 95%CI: 1.21–4.21).ConclusionThe prognosis of patients will be adversely affected if the IC‐RT exceeds 40 days, especially for stage IVa patients.
Neoadjuvant chemotherapy plus concurrent chemoradiotherapy versus concurrent chemoradiotherapy alone in elderly patients with stage III‐IVa nasopharyngeal carcinoma: A real‐world study based on medical comorbidities
Authors: Jin Ya‐Nan , Xiao Zhi‐Wen , Yao Wei , Yu Jing , Zhang Wang‐Jian , Marks Tia , Zhang Hong‐Yu , Yao Ji‐Jin , Xia Liang‐Ping 
Published: February 2024

AbstractPurposeTo evaluate the outcomes and toxicities of adding neoadjuvant chemotherapy (NAC) to concurrent chemoradiotherapy (CCRT) in elderly (≥65 years) patients with locoregionally advanced nasopharyngeal carcinoma (LANPC, stage III‐IVa).Methods and MaterialsUsing an NPC‐specific database, 245 elderly patients with stage III‐IVa NPC, receiving CCRT +/− NAC, and an Adult Co‐morbidity Evaluation 27 (ACE‐27) score <2 were included. Recursive partitioning analysis (RPA) based on TNM stage and Epstein–Barr virus (EBV) DNA were applied for risk stratification. The primary end point was disease‐free survival (DFS).ResultsTwo risk groups were generated by the RPA model. In the high‐risk group (EBV DNA < 4000 copy/ml with stage IVa & EBV DNA ≥4000 copy/ml with stage III‐IVa), patients treated with NAC plus CCRT achieved improved 5‐year DFS rates compared to those who received CCRT alone (56.9% vs. 29.4%; p = 0.003). But we failed to observe the survival benefit of additional NAC in the low‐risk group (EBV DNA <4000 copy/ml with stage III). The most common severe acute toxic effects were leucopenia (46.8% vs. 24.4%) and neutropenia (43.7% vs. 20.2%) in the NAC plus CCRT group versus CCRT group with statistically significant differences.ConclusionsThe addition of NAC to CCRT was associated with better DFS for the high‐risk group of elderly LANPC patients with ACE‐27 score <2. However, the survival benefit of additional NAC was not observed in low‐risk patients.
Effects of the active botanical blend “WKUP GT” on attention and cognitive functions after lunch in healthy volunteers
Authors: Nadam Irit Schwartz , Bellamine Aouatef , Salom Rafael , Guilera Sonia , Inarejos‐Garcia A. M. , Pillar Giora 
Published: February 2024

AbstractObjectives“WKUP GT”, a low caffeine beverage consisting of carob, Guarana, Green Tea and Elderberry extracts was studied on attention and cognitive functions post‐lunch in a pilot randomized double blind placebo controlled trial.MethodsThirty healthy volunteers were included in a crossover design trial, presenting five beverages randomly assigned to the following groups: placebo, “WKUP GT” (single, double or triple doses), or “caffeine” as an active control. Hemodynamic measurements were assessed as safety outcomes.The Cambridge Neuropsychological Test Automated Battery (CANTAB), was used to evaluate the patients when beverages were consumed 30 and 120 min after lunch (respectively Delta30 and Delta120 considering baseline).ResultsDrinking “caffeine” or “WKUP GT” after lunch, showed significant improvement (p < 0.05) in rapid visual information processing compared to placebo (Delta120 of “caffeine”, “WKUP” single and double). In addition, improvement in Multitasking Test (Delta30 for “WKUP” double, and Delta120 for “caffeine” and “WKUP” triple compared to placebo) was observed. “WKUP” triple also showed significant improvement for “memory” when compared to placebo (Delta120). Compared to “caffeine”, WKUP GT did not increase systolic blood pressure.Conclusion“WKUP GT” showed improvements for attention, memory, psychomotor and executive function tasks after lunch without increase in pulse rate.
Efficacy and immunogenicity of AS04‐HPV‐16/18 vaccine in females with existing cervical HR‐HPV infection at first vaccination: A pooled analysis of four large clinical trials worldwide
Authors: Wen Tian‐Meng , Xu Xiao‐Qian , Zhao Xue‐Lian , Pan Cheng‐Hao , Feng Yu‐Shu , You Ting‐Ting , Gao Meng , Hu Shang‐Ying , Zhao Fang‐Hui 
Published: February 2024

AbstractFemales with existing high‐risk HPV (HR‐HPV) infections remain at risk of subsequent multiple or recurrent infections, on which benefit from HPV vaccines was under‐reported. We pooled individual‐level data from four large‐scale, RCTs of AS04‐HPV‐16/18 vaccine to evaluate efficacy and immunogenicity in females DNA‐positive to any HR‐HPV types at first vaccination. Females receiving the AS04‐HPV‐16/18 vaccine in the original RCTs constituted the vaccine group in the present study, while those unvaccinated served as the control group. Vaccine efficacy (VE) against new infections and associated cervical intraepithelial neoplasia (CIN) 2+ in females DNA‐negative to the considered HR‐HPV type but positive to any other HR‐HPV types, VE against reinfections in females DNA‐positive to the considered HR‐HPV type but cleared naturally during later follow‐up, and levels of anti‐HPV‐16/18 IgG were assessed. Our final analyses included 5137 females (vaccine group = 2532, control group = 2605). The median follow‐up time was 47.88 months (IQR: 45.72‐50.04). For the prevention of precancerous lesions related to the non‐infected HR‐HPV types at baseline, VE against HPV‐16/18 related CIN 2+ was 82.70% (95% CI: 63.70‐93.00%). For the prevention of reinfections related to the infected HR‐HPV types following natural clearance, VE against HPV‐16/18 12MPI was non‐significant (p > .05), albeit robust immunity persisted for at least 48 months. Females with existing HR‐HPV infections at first vaccination still benefit from vaccination in preventing precancers related to the non‐infected types at baseline. VE against reinfections related to the infected types following natural clearance remains to be further investigated.
Quality and comprehensiveness of YouTube videos on back pain during pregnancy
Authors: Karataş Özlem , Karataş Selim 
Published: February 2024

AbstractObjectivesBack pain during pregnancy is a common issue that impacts the quality of life for many women. YouTube has become an increasingly popular source of health information. Pregnant women often turn to YouTube for advice on managing back pain, but the quality of available videos is highly variable. This study aimed to assess the quality and comprehensiveness of YouTube videos related to back pain during pregnancy.MethodsA YouTube search was conducted using the keyword “back pain in pregnancy”, and the first 100 resulting videos were included in the study. After a thorough review and exclusion of ineligible videos, the final sample consisted of 71 videos. Various parameters such as the number of views, likes, viewer interaction, video age, uploaded source (healthcare or nonhealthcare), and video length were evaluated for all videos.ResultsRegarding the source of the videos, 44 (61.9%) were created by healthcare professionals, while 27 (38%) were created by nonprofessionals. Videos created by healthcare professionals had significantly higher scores in terms of DISCERN score, Journal of the American Medical Association (JAMA) score, and Global Quality Scale (GQS) (P < 0.001). Our findings indicate a statistically significant and strong positive correlation among the three scoring systems (P < 0.001).ConclusionVideos created by healthcare professionals were generally of higher quality, but many videos were still rated as low‐moderate quality. The majority of videos focused on self‐care strategies, with fewer discussing other treatment options. Our findings highlight the need for improved quality and comprehensiveness of YouTube videos on back pain during pregnancy.
Methods for aggregating multi‐source heterogeneous data in the IoT based on digital twin technology
Authors: Li Min 
Published: February 2024

AbstractThe Internet of Things (IoT) technology can currently enable devices and systems in various fields to achieve interconnectivity, intelligence, and automation, which is significant for improving daily life. It connects objects through the Internet, achieving information exchange and sharing, bringing many conveniences to humanity, and improving the efficiency and quality of various industries. However, precisely because everything is interconnected, most IoT systems have high data throughput, which leads to issues such as reduced operational efficiency of IoT systems. Therefore, this article used digital twin (DT) technology to aggregate multi‐source heterogeneous data of the IoT, overcoming the problems of diversity and differences in massive data, and thus accelerating the system's data processing. Moreover, in the end of this article, an experiment was conducted on the IoT system of a certain university. Taking the system running 10 times as an example, the packet loss rate of the experimental group using DT technology was only 3.48%, while the packet loss rate of the control group running alone was 4.36%. This indicates that DT technology has improved the performance of the IoT system. This study highlights the role of digital twin technology in solving the low operational efficiency, diverse data, and data differences in data aggregation of the Internet of Things. It plays a significant role in improving the operational efficiency of the Internet of Things and improving the performance of the Internet of Things system.
Impact of microfinance on income generation: Evidence from a rural community‐driven development programme in Myanmar
Authors: Chung Jongwoo , Kim Booyuel 
Published: February 2024

AbstractThis paper evaluates the impact of a rural community‐driven development programme in Myanmar, which promoted village‐level microfinance for income generation. Utilizing a three‐round household survey consisting of 100 treatment and 50 comparison villages with approximately 8500 households per round, we employ difference‐in‐differences and two‐stage least squares estimations. Our analysis shows three key findings. First, the programme significantly increased access to microfinance, primarily for production. Second, formal and informal finance were substituted in part with village‐level microfinance. As a result, treated households were less likely to borrow money from formal banks or informal lenders such as their relatives, friends or neighbours. Third, the village‐level microfinance nudged rural households to harvest, yield and sell their products more, which led to increase in seasonal income. Our study suggests that microfinance targeted for productive investment can significantly improve income of rural households in developing economies.
The effect of tessellation on stiffness in the hyoid arch of elasmobranchs
Authors: Wilga Cheryl , Dumont Elizabeth , Ferry Lara 
Published: February 2024

AbstractTessellated cartilage forms much of the skeleton of sharks and rays, in contrast to most other aquatic vertebrates who possess a skeleton of bone. Interestingly, many species of sharks and rays also regularly generate exceptionally high forces in the execution of day‐to‐day activities, such as when feeding on bony fish, mammals, and hard‐shelled invertebrates. Tessellated cartilage differs from other types of cartilage in that they are covered by an outer layer of small mineralized tiles (tesserae) that are connected by fibrous connective tissue. Tesserae, therefore, are hypothesized to play a role in stiffening the cartilaginous skeleton for food capture and other activities that require the generation of high forces. In this study, the hyomandibula and ceratohyal cartilages, which support the jaw and throat regions of sharks and rays, were tested under compressive load in a material testing system to determine the contribution of tesserae to stiffness. Previous hypotheses suggest an abrupt upward shift in the slope of the stress–strain curve in tessellated materials due to collision of tesserae. Young's Modulus (E) was calculated and used to evaluate cartilage stiffness in a range of elasmobranch species. Our results revealed that there was an abrupt shift in Young's Modulus for elements loaded in compression. We postulate that this shift, characterized by an inflection point in the stress–strain curve, is the result of the tesserae approaching one another and compressing the intervening fibrous tissue, supporting the hypothesis that tesserae function to stiffen these cartilages under compressive loading regimes. Using published data for nontessellated cartilage for comparison, we show that this shift is, as expected, unique to tessellated cartilage.
Parameteric optimization of SiGe S/D NT JLFET using analytical modeling to improve L‐BTBT induced GIDL
Authors: Thakur Anchal , Dhiman Rohit , Wadhwa Girish , Bhandari Sheetal 
Published: February 2024

AbstractIn the present work, we investigate the impact of structure dimensional parameters on the short channel effects which occurs especially below 20 nm regime particularly gate induced drain leakage (GIDL) current. Using technology computer aided design simulation (TCAD), we have examined the GIDL for SiGe as source/drain in NTJLFET. The structural dimensional parameters such as the nanotube thickness, core and outer gates thickness and gate electrode work function shows the significant impact on the band to band tunneling in lateral direction (L‐BTBT) which induced GIDL current. It is analyzed that increase in the nanotube thickness and physical oxide thickness increase the GIDL current, while increasing the gate electrode work function, core gate and outer gate thicknesses gives reduced GIDL current. The SiGe S/D NTJLFET produce a remarkable high ION/IOFF ratio ~ 1011. A compact model for GIDL current is also developed which shows the dependency of structure parameters on leakage current. The SiGe has been incorporated as source and drain in NTJLFET which creates the energy band discontinuity. Furthermore, SiGe S/D NTJLFET is fairly compared with the conventional NT JLFET and nanowire (NW) JLFET and shows an improved performance.
Comparison of iliopsoas tendonitis after hip resurfacing arthroplasty and total hip arthroplasty: A case‐controlled investigation using a validated simulation
Authors: Hardwick‐Morris Max , Twiggs Joshua , Miles Brad , Al‐Dirini Rami M. A. , Taylor Mark , Balakumar Jitendra , Walter William L. 
Published: February 2024

AbstractIliopsoas tendonitis, typically caused by impingement with the acetabular cup, occurs in up to 18% of patients after total hip arthroplasty (THA) and up to 30% of patients after hip resurfacing arthroplasty (HRA). We have developed a simulation for detecting iliopsoas impingement and validated it in a previous study of THA patients. However, due to the difference in incidence between HRA and THA, this study had two aims. First, to validate the simulation in a cohort of HRA patients and, second, to comparethe results of the HRA and THA patients to understand any differences in their etiology. We conducted a retrospective search in an experienced surgeon's database for HRA patients with iliopsoas tendonitisand control patients without iliopsoas tendonitis, resulting in two cohorts of 12 patients. Using CT scans, 3D models of the each patient's prosthetic and bony anatomy were generated, landmarked, and simulated. Regarding validation of the simulation for HRA patients, impingement significantly predicted the probability of iliopsoas tendonitis in logistic regression models and the simulation had a sensitivity of 83%, specificity of 100%, and an AUC ROC curve of 0.95. Unexpectedly, the HRA cohort exhibited less impingement than the THA cohort. Our novel simulation has now been demonstrated to detect iliopsoas impingement and differentiate between the symptomatic and asymptomatic cohorts in investigations of THA and HRA patients. This tool has the potential to be used preoperatively, to guide decisions about optimal cup placement, and postoperatively, to assist in the diagnosis of iliopsoas tendonitis.