bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mental health among people with a migration background in Belgium over the past 20 years: how has the situation evolved?
Authors: Duveau Camille , Smith Pierre , Lorant Vincent 
Published: September 2023

Abstract
Background
Poor mental health is highly stigmatized and stereotyped, even more when it comes to migrant and ethnic minority groups (MEM). Belgium, which has a long history of immigration, is a good case study for analysing how the prevalence of mental illness (MI) has evolved over time and how such evolution had differed between MEM. This paper seeks to explore the prevalence of MI and potential inequalities among MEM compared to native Belgians between 1997 and 2018, shedding light on this important issue.

Methods
The data set is composed of the six cross-sectional waves of the Belgian Health Interview Survey from 1997 to 2018. The 12-item General Health Questionnaire was used to assess the average level of mental health and the prevalence of MI (score ≥ 4) among five major MEM groups in Belgium (Belgian, Moroccan, Turkish, European migrants, and non-European migrants). Multivariate logistic and linear regression models were used to assess the likelihood of having a MI in the different MEM groups and survey years. The minimal clinically important difference (MID) was also calculated for the severity of MI.

Results
After controlling for socioeconomic status, the average marginal effect indicated a decrease in mental health among Moroccans and Turks in Belgium between 1997 and 2018, compared to Belgians. This result was confirmed by the Chi²-test, which showed that Turkish (χ²=17.75, p < 0.001) and Moroccans respondents (χ²=4.19, p < 0.04) had a higher overall level of mental distress than Belgians. Furthermore, in 2018, even after adjusting for age, sex and education level, having a mother born in a non-EU country increased the risk of mental illness.

Conclusions
Mental health inequalities between migrant and ethnic groups are on the rise in Belgium. To address this issue, particular attention should be given to the Moroccan and Turkish background populations. Specific interventions and policies must be implemented to prevent the increase of psychological distress among migrants and ethnic minorities, on the one hand, and ensure that high-quality mental health care is accessible to all, regardless of ethnicity, on the other hand. Additionally, we recommend that future research on ethnic mental healthcare includes better data collection on the country of birth of respondents and their parents.
Automatic DNN architecture design using CPSOTJUTT for power system inspection
Authors: Lv Xian-Long , Chiang Hsiao-Dong , Dong Na 
Published: September 2023

AbstractTo quickly and accurately automatically design more high-precision deep neural network models (DNNs), this paper proposes an automatic DNN architecture design ensemble model based on consensus particle swarm optimization-assisted trajectory unified and TRUST-TECH (CPSOTJUTT), called CPSOTJUTT-EM. The proposed model is a three-layer model, and its core is a three-stage method for addressing the sensitivity of the local solver to the initial point and enabling fast and robust training DNN, effectively avoiding missing high-quality DNN models in the process of automatic DNN architecture design. CPSOTJUTT has the following advantages: (1) high-quality local optimal solutions (LOSs) and (2) robust convergence against random initialization. CPSOTJUTT-EM consists of the bottom layer: stable and fast design high-quality DNN architectures, the middle layer: exploration for a diverse set of optimal DNN classification engines, and the top layer: ensemble model for higher performance. This paper tests the performance of CPSOTJUTT-EM on public datasets and three self-made power system inspection datasets. Experimental results show that the CPSOTJUTT-EM has excellent performance in automatic DNN architecture design, DNN model optimization. And the CPSOTJUTT-EM can automatically design high-quality DNN ensemble models, laying a solid foundation for the application of DNN in other fields.
Neurofilament light chain on intensive care admission is an independent predictor of mortality in COVID-19: a prospective multicenter study
Authors: Sievert Theodor , Didriksson Ingrid , Spångfors Martin , Lilja Gisela , Blennow Kaj , Zetterberg Henrik , Frigyesi Attila , Friberg Hans 
Published: September 2023

Abstract
Background
Neurofilament light chain (NfL), glial fibrillary acidic protein (GFAP), and total-tau protein (tau) are novel blood biomarkers of neurological injury, and may be used to predict outcomes in critical COVID-19.

Methods
A prospective multicentre cohort study of 117 consecutive and critically ill COVID-19 patients in six intensive care units (ICUs) in southern Sweden between May and November 2020. Serial NfL, GFAP and tau were analysed in relation to mortality, the Glasgow Outcome Scale Extended (GOSE) and the physical (PCS) and mental (MCS) components of health-related quality of life at one year.

Results
NfL, GFAP and tau on ICU admission predicted one-year mortality with an area under the curve (AUC) of 0.82 (95% confidence interval [CI] 0.74$$-$$
-
0.90), 0.72 (95% CI 0.62$$-$$
-
0.82) and 0.66 (95% CI 0.54$$-$$
-
0.77). NfL on admission was an independent predictor of one-year mortality (p = 0.039). Low NfL and GFAP values were associated with good PCS ($$\ge$$
≥
45) at one year but not with good MCS ($$\ge$$
≥
45) or GOSE ($$\ge$$
≥
5).

Conclusions
NfL on ICU admission was an independent predictor of mortality. High levels of NfL, GFAP and tau were associated with mortality but not with poor GOSE in survivors at one year. Low levels of NfL and GFAP were associated with improved physical health-related quality of life.

Graphical Abstract
Cardiac hydatidosis complicated by vascular involvement: a case report
Authors: Gupta Vidushi , Bansal Kalpana , Gupta Pranav , Sharma Neha , Naqvi Sayyed Ehtesham Hussain 
Published: September 2023

Abstract
Background
Hydatid disease is a parasitic infection which is endemic in multiple regions across the globe including Indian subcontinent. Although it commonly affects the liver and other solid organs, isolated involvement of the heart is relatively uncommon. Cardiac hydatidosis can be confidently diagnosed on echocardiography, but cross-sectional imaging by computed tomography (CT) or magnetic resonance imaging (MRI) provides accurate information about its location, extent, and multiplicity. Multiple case studies of cardiac hydatid disease have been reported in the literature. However, cardiac hydatidosis with extension into pulmonary vasculature has not been reported commonly. This case report highlights this rare association, with stress upon the altered surgical management.

Case presentation
A 50-year-old patient presented with atypical chest pain to the cardiology department of a tertiary care hospital where he underwent multiple blood tests as well as electrocardiography (ECG) and echocardiography as part of the routine examination. Echocardiography revealed a large, multicystic mass invading the posterolateral wall of left ventricle (LV) with no internal vascularity and was provisionally diagnosed as hydatid disease. Subsequent CT study confirmed a large multicystic lesion with the presence of another smaller lesion invading the left atrial appendage (LAA). In order to evaluate the vascular and mediastinal invasion, cardiac MRI was then performed which revealed invasion of right pulmonary artery (PA), right superior pulmonary vein (PV) as well as compression of superior vena cava (SVC) by the smaller lesion. A final diagnosis of cardiac hydatidosis with invasion into right PA and right superior PV was made. Treatment plan for the patient changed, who then underwent an additional reconstruction of right PA and right superior PV after cyst removal.

Conclusions
Cardiac hydatid disease is a rare but potentially lethal condition, which tends to show slow growth and local invasion. The diversity of findings in such rare cases makes individual surgical approach extremely valuable with preoperative radiological imaging becoming indispensable for correct localization and appropriate planning. Our case report highlights rare association of cardiac hydatidosis with invasion of both pulmonary artery and vein, which eventually altered the surgical management of patient.
Inline induction heating for high-pressure fuel-based testing applications
Authors: Thampy Tom , Rivington Emmanuel Gospel Raj , Avulapati Madan Mohan , Murthy Niroop Srinivasa 
Published: September 2023

AbstractInduction heating offers numerous advantages over conventional methods for heating high-pressure fluids in hydraulic testing applications. It simplifies complex processes, mitigates the risks associated with high-pressure environments, and enhances overall safety. The design of an efficient induction heating system requires a clear understanding of its key components, including the resonant tank circuit, impedance matching and isolation stage, high-frequency inverter, driver circuitry, and controller. The configuration of the resonant circuit plays a crucial role in device ratings and control methods. To meet the demanding requirements of switching devices like IGBTs, the driver circuit must ensure high immunity to interferences and failure. Effective system design allows the heating circuit to operate close to resonant switching, minimizing switching losses and cooling requirements. This paper presents the design and development of a 4-kW induction heater specifically tailored for inline heating of aviation fuel under high pressure. The system aims to achieve a precise temperature profile for testing line-replaceable units (LRUs) used in aircraft. The design methodology encompasses the selection of the resonant tank circuit configuration, impedance matching and isolation stage, high-frequency inverter, driver circuitry, and control strategies. Through extensive simulations in LTspice and experimental measurements, power losses in different components of the power conversion circuits are assessed, and overall system efficiency is evaluated. The results demonstrate the proposed induction heating system’s remarkable energy efficiency, reduced switching losses, and improved reliability. Furthermore, a comprehensive comparison with existing designs and industry norms is presented, highlighting the distinct advantages of the proposed system in terms of cost-effectiveness, energy efficiency, material utilization, and processing time. This research contributes valuable insights into the design and optimization of induction heating systems for high-pressure fluid heating applications, providing a practical and efficient solution for the aviation industry.
Suppression of Endogenous Insulin Secretion by Euglycemic Hyperinsulinemia
Authors: Karakaplan Nesrin Damla , Song Yilin , Laurenti Marcello C , Vella Adrian , Jensen Michael D 
Published: September 2023

Abstract

Context
The impact of insulin, particularly exogenous hyperinsulinemia, on insulin secretion in humans is debated.

Objective
We assessed the effects of exogenous hyperinsulinemia on insulin secretion and whether the response is altered in insulin resistance associated with obesity.

Methods
Insulin secretion rates (ISRs) during euglycemic hyperinsulinemic clamp studies (52 volunteers) were calculated using a model that employs plasma C-peptide concentrations. One study involved a 2-step insulin clamp and the other study was a single step insulin clamp. For both studies the goal was to achieve plasma glucose concentrations of 95 mg/dL during the clamp irrespective of fasting glucose concentrations. The percent change in ISR from fasting to the end of the insulin clamp interval was the main outcome. Linear regression and analysis of covariance were used to test for the effects of insulin on ISR and to test for group differences.

Results
ISR was greater in obese volunteers (P &lt; .001) under fasting and hyperinsulinemic clamp conditions. The change in plasma glucose from baseline to the end of the insulin clamp interval was highly correlated with the change in ISR (r = 0.61, P &lt; .001). From baseline to the end of the clamp we observed a 27% (SD 20) suppression of ISR. The participants who underwent a 2-step insulin clamp had greater suppression of ISR during the second step than the first step (P &lt; .001). The proportional suppression of ISR during euglycemic hyperinsulinemia was not different between nonobese and obese groups (P = .19).

Conclusion
Hyperinsulinemia suppresses endogenous insulin secretion and the relative change in insulin secretion produced by exogenous insulin did not differ between nonobese and obese people.
Legacy and Emerging Perfluoroalkyl and Polyfluoroalkyl Substances Regulate Steroidogenesis in the Male Gonad
Authors: Daugherty Samantha , Mulabagal Vanisree , Hayworth Joel , Akingbemi Benson T 
Published: September 2023

Abstract
Perfluoroalkyl and polyfluoroalkyl substances (PFAS) are widely used in a variety of industrial processes and manufacturing of consumer products. Current efforts by the manufacturing industry will limit use of long-chain or legacy PFAS represented by perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS) and replace with short-chain or emerging PFAS such as perfluorobutanoic acid (PFBA) and perfluorobutane sulfonic acid (PFBS). However, there is little to no information on the toxicity of new and emerging PFAS. Therefore, we performed experiments in growing Long–Evans male rats to investigate effects of low-dose prepubertal and pubertal exposures to PFAS on gonadal steroid hormone secretion. The results demonstrated that both legacy and emerging PFAS have the capacity to regulate testicular steroidogenesis. For instance, prepubertal exposures to PFOS, PFBA, and PFBS increased serum and testicular testosterone concentrations. Exposure to PFBA increased testicular 17β-estradiol (E2) concentrations, and PFOS and PFBS both decreased serum E2 concentrations while stimulating testicular E2 secretion. The data also demonstrated additive effects due to legacy and emerging PFAS mixtures compared with the individual chemicals. The gonadal effects due to PFAS exposures occurred at nanomolar concentrations, which approximate PFAS levels in the environment. Taken together, the present study supports the need for development of cost-effective and sustainable filtration media for different processes to remove PFAS from water and other sources of exposure. Current action by regulatory agencies such as the US Environmental Protection Agency to limit use of PFAS in the manufacture of consumer products will protect public health.
El milagro, el despertar y la fiesta
Authors: Medel Juan Carlos 
Published: September 2023

Abstracto
En este ensayo el autor reflexiona críticamente en torno al Chile neoliberal de los últimos 40 años. A partir del texto La Sociedad del Cansancio de Byung-Chul Han, ofrece una interpretación del estallido social chileno. Argumenta que el estallido social de octubre del 2019 expresa un profundo rechazo del modelo económico existente, poniendo énfasis en las consecuencias culturales de dicho modelo, cuestionando las prácticas de autoexplotación impuestas por la cultura laboral neoliberal. En la primera parte del texto desarrolla una aproximación crítica a la figura del emprendedor, encarnación de la ideología de la meritocracia y piedra angular del proyecto neoliberal en Chile. Después de eso propone una argumentación sobre las fuerzas históricas que explican el estallido social y las diferentes formas de resistencia expresadas a partir de entonces. Por último, concluye con una invitación a repensar el trabajo y su rol en un futuro Chile postneoliberal.
On the Minute Structure of involuntary muscular fibre
Authors: Lister Joseph , Christison Dr. 
Published: September 2023

ABSTRACT
It has been long known that contractile tissue presents itself in the human body in two forms, one composed of fibres of considerable magnitude, and therefore readily visible under a low magnifying power, and marked very characteristically with transverse lines at short intervals, the other consisting of fibres much more minute, of exceedingly soft and delicate aspect, and destitute of transverse striae. The former variety constitutes the muscles of the limbs, and of all parts whose movements are under the dominion of the will; while the latter forms the contractile element of organs, such as the intestines, which are placed beyond the control of volition. There are, however, some exceptions to this, general rule, the principle of which is the heart, whose fibres are a variety of the striped kind.
On a Mode of Reproduction by Spontaneous Fission in the Hydroida
Authors: Allman  
Published: September 2023

ABSTRACT
The hydroid which presents the remarkable mode of reproduction about to be described was obtained in Loch Long, on the west coast of Scotland. It is a Campanularidan, profusely branched with its trophosome, bearing considerable resemblance to that of Obelia didiotoma, No gonosome, however, was present in any of the specimens collected; and though I believe that there are sufficient’grounds for regarding it as generically distinct from all previously described hydroids, its exact systematic position cannot, in the absence of a gonosome, be assigned otherwise than provisionally.
Evidence for multi-scale power amplification in skeletal muscle
Authors: Petersen Jarrod C. , Roberts Thomas J. 
Published: September 2023

ABSTRACT
Many animals use a combination of skeletal muscle and elastic structures to amplify power output for fast motions. Among vertebrates, tendons in series with skeletal muscle are often implicated as the primary power-amplifying spring, but muscles contain elastic structures at all levels of organization, from the muscle tendon to the extracellular matrix to elastic proteins within sarcomeres. The present study used ex vivo muscle preparations in combination with high-speed video to quantify power output, as the product of force and velocity, at several levels of muscle organization to determine where power amplification occurs. Dynamic ramp-shortening contractions in isolated frog flexor digitorum superficialis brevis were compared with isotonic power output to identify power amplification within muscle fibers, the muscle belly, free tendon and elements external to the muscle tendon. Energy accounting revealed that artifacts from compliant structures outside of the muscle–tendon unit contributed significant peak instantaneous power. This compliance included deflection of clamped bone that stored and released energy contributing 195.22±33.19 W kg−1 (mean±s.e.m.) to the peak power output. In addition, we found that power detected from within the muscle fascicles for dynamic shortening ramps was 338.78±16.03 W kg−1, or approximately 1.75 times the maximum isotonic power output of 195.23±8.82 W kg−1. Measurements of muscle belly and muscle–tendon unit also demonstrated significant power amplification. These data suggest that intramuscular tissues, as well as bone, have the capacity to store and release energy to amplify whole-muscle power output.
Respirometry reveals major lineage-based differences in the energetics of osmoregulation in aquatic invertebrates
Authors: Cochran Jamie K. , Banks Catelyn , Buchwalter David B. 
Published: September 2023

ABSTRACT
All freshwater organisms are challenged to control their internal balance of water and ions in strongly hypotonic environments. We compared the influence of external salinity on the oxygen consumption rates (ṀO2) of three species of freshwater insects, one snail and two crustaceans. Consistent with available literature, we found a clear decrease in ṀO2 with increasing salinity in the snail Elimia sp. and crustaceans Hyalella azteca and Gammarus pulex (r5=−0.90, P=0.03). However, we show here for the first time that metabolic rate was unchanged by salinity in the aquatic insects, whereas ion transport rates were positively correlated with higher salinities. In contrast, when we examined the ionic influx rates in the freshwater snail and crustaceans, we found that Ca uptake rates were highest under the most dilute conditions, while Na uptake rates increased with salinity. In G. pulex exposed to a serially diluted ion matrix, Ca uptake rates were positively associated with ṀO2 (r5=−0.93, P=0.02). This positive association between Ca uptake rate and ṀO2 was also observed when conductivity was held constant but Ca concentration was manipulated (1.7–17.3 mg Ca l−1) (r5=0.94, P=0.05). This finding potentially implicates the cost of calcium uptake as a driver of increased metabolic rate under dilute conditions in organisms with calcified exoskeletons and suggests major phyletic differences in osmoregulatory physiology. Freshwater insects may be energetically challenged by higher salinities, while lower salinities may be more challenging for other freshwater taxa.
The Effect of Mixed Ligands on the Polymerization Rate of SET-LRP in Aqueous Solution
Authors: Feng Xiaojing , Yuan Wenxia 
Published: September 2023

Abstract
The mixed-ligand effect is investigated in single electron transfer-living radical polymerization (SET-LRP) of OEOMA in aqueous solution for the first time. Mediated by equimolar tris(2-aminoethyl)amine (TREN) and tris(dimethylaminoethyl)amine (Me6-TREN), SET-LRP exhibits the highest polymerization rate while maintaining living characteristics. The higher concentration of self-assembled micellar particles formed by amphiphilic initiator and monomer in aqueous solution under the influence of mixed ligands may be considered as one of factors for the mixed-ligand effect.
Circadian disruption does not alter tumorigenesis in a mouse model of lymphoma
Authors: Mello Rebecca M , Pariollaud Marie , Lamia Katja A 
Published: September 2023

Background: Disruption of natural light cycles, as experienced by shift workers, is linked to enhanced cancer incidence. Several mouse models of cancer develop more severe disease when exposed to irregular light/dark cycles, supporting the connection between circadian disruption and increased cancer risk. Cryptochrome 2 (CRY2), a repressive component of the molecular circadian clock, facilitates turnover of the oncoprotein c-MYC, one mechanism that may link the molecular clock to tumorigenesis. In Eμ-MYC mice, which express transgenic c-MYC in B cells and develop aggressive lymphomas and leukemia, global Cry2 deletion reduces survival and enhances tumor formation. Lighting conditions that mimic the disruption experienced by shift workers dampen Cry2 transcripts in peripheral tissues of C57BL/6J mice. Although it is milder than homozygous deletion of Cry2, we hypothesized that reduced Cry2 rhythmicity could alter MYC protein accumulation and contribute to enhanced cancer risk caused by circadian disruption. We tested this hypothesis in MYC-driven lymphoma. Methods: We housed Eμ-MYC mice in light-tight boxes set to either control (continuous cycles of 12-hours of light followed by 12-hours of dark, LD12:12) or chronic jetlag (eight-hour light phase advances every two to three days, CJL) lighting conditions and assessed the impact of disrupted light cycles on survival and tumor formation in Eμ-MYC mice. Results: Environmental disruption of circadian rhythms did not alter tumor location, tumor growth, or survival in Eμ-MYC mice. Conclusions: Dampened rhythms of Cry2 following disruption of circadian light exposures is milder than deletion of Cry2. The lack of phenotype caused by altered circadian gene expression in contrast to enhanced tumorigenesis caused by homozygous deletion of Cry2 suggests that CRY2 dosage impacts this model. Importantly, these findings indicate that increased cancer risk associated with circadian disruption arises from one or more mechanisms that are not recapitulated here, and may be different in distinct tumor types.