bluuebunny/crossref_metadata_2025_split huggingface dataset:
Whole Genome Sequence Analysis of Six SARS-CoV-2 Positive Patients Followed in a Tertiary University Hospital
Authors: KEPENEK KURT Esma , ÖZDEMİR Mehmet , ESENKAYA TAŞBENT Fatma , ERAYMAN İbrahim 
Published: October 2023

Aims: In this study, we aimed to determine mutations in the gene sequence of this virus, by performing whole genome sequence analysis from patient samples found positive by actual RT-PCR (PCR) for SARS-CoV-2.
Methods: The study included six adult patient samples with different clinical manifestations with positive PCR tests for SARS-CoV-2, between June 01, 2020, and March 12, 2021. Sequence knowledge of all samples/testers has been loaded into the GISEAD (Global Initiative on Sharing All Influenza Data) data system. Clade Analysis, Genome Analysis, Variant Analysis, and Phylogenetic Tree Analysis were conducted.
Results: 3 of the patients were women (female), and three were men(male), with the mean age of 42.5 years old (between 20 - 61). Totally 71 mutations were specified in 6 adult patients. By the Pangolin lineage, three of the patients were B.1.177, two were B.1, one was of B1.36 lineage. By the Pango lineage, two of the patients were B.1.609, one was B.177, one was B.1.36. By the Nexstrain Clade, four of the patients were 20A and two were of 19A lineage. No D614G mutation was detected in any of the patients. While five patients recovered, one patient with metastatic lung adenocarcinoma died.
Conclusion; The patients were detected in the commonly found 'Non-VOC' group. Therefore, variants could not be associated with the clinical status and prognosis of the patients. However, it is thought that the data obtained contribute to both global and national SARS-CoV-2 data.
Unveiling the Prognostic Significance of Immature Granulocytes and Nucleated Red Blood Cells in Geriatric Pneumonia Severity and Mortality Outcomes
Authors: AKAY ÇİZMECİOGLU Hilal , GÖKTEPE Mevlüt Hakan , CİZMECİOGLU Ahmet 
Published: October 2023

Aim: The progression of pneumonia in the senior-age population can be catastrophic. Biomarkers capable of assessing the severity of pneumonia play a pivotal role in prognosis. We conducted an evaluation of the kinetics of immature granulocytes (IG) and nucleated red blood cells (NRBC) as potential indicators of the severity of geriatric pneumonia.
Materials & Methods: In this retrospective cross-sectional study, patients diagnosed with pneumonia were categorized using two prominent severity scoring systems, CURB-65 (Confusion, Urea, Respiratory rate, Blood pressure, age >65) and PSI (Pneumonia severity index). Additionally, the patients' discharge status and infection process markers were noted.
Results: A total of 80 patients were included in the evaluation, with a mean age of 72.23 ± 7.26. Excluding the mortality rate of 49% when including oncology patients, the overall mortality rate was 26%. The deceased patients had longer hospitalization durations, higher CURB-65 and PSI category classifications, and elevated NRBC results. In CURB-65-based categorization, there was an increase only in NRBC levels associated with disease severity, whereas, in PSI-based categorization, there was an increase in both NRBC and IG levels. No statistical difference was observed in NRBC and IG levels when excluding oncology patients from the analysis.
Conclusion: In geriatric pneumonia cases, the dynamics of NRBC appear to be more crucial in indicating disease severity compared to IG. However, this opportunity seems to be missed or compromised in patients with oncological comorbidities.
Evaluation of Scientific Publications on Osteoblastoma Published between 2000 and 2022
Authors: YILMAZ Selçuk , KURT Mehmet 
Published: October 2023

Objective: The aim of this bibliometric study was to review the scientific outputs published between 2000 and 2022 on osteoblastoma, a benign aggressive bone tumor.
Methods: Scientific research articles on osteoblastoma published between 2000 and 2022 were targeted and data were obtained from the Web of Science database. The data obtained were analyzed and visualized using bibliometric programs.
Results: A total of 679 articles about osteoblastoma published between 2000-2022 met our inclusion criteria. Most of the articles on osteoblastoma (n=48) were published in 2020. There was no noteworthy peak in the trend of the number of publications between 2000 and 2022. These articles cited 10366 times in total and 15.27 times per article. At least 62 various countries and regions took part in osteoblastoma publishing research over the past 22 years. The United States (192) was the largest contributor to osteoblastoma publications followed by China (60), India (51), Italy (50), and Turkey (46). The United States was the country that published the most publications in all years between 2000 and 2022. Especially China's publications increased in 2022. The United States was also the country with the highest level of publication collaboration (such as citation and co-authorship) among countries.
Conclusion: The number of published articles is well below the expected level. Although the number of scientific publications from China has increased in recent years, the United States still ranks first.
Threat of mpox (monkeypox) outbreak after the COVID-19 pandemic: are healthcare professionals ready for new psychological wars?
Authors: ÇELİK Mehmet , ACAR Ufuk , AKGUL Fethiye , ARSLAN Yusuf , CEYLAN Mehmet Reşat 
Published: October 2023

Aims: In this study, it was aimed to evaluate the psychological status of healthcare professionals regarding the COVID-19 pandemic, and to examine their perspectives and knowledge levels regarding the mpox epidemic.
Methods: Having a cross-sectional design, the present study was carried out by using questions addressing sociodemographic characteristics of healthcare professionals, their experiences with the COVID-19 pandemic, and their knowledge and anxiety levels regarding mpox.
Results: 202 healthcare professionals were involved in the present study. Of the participants, 55% were female and the mean age was 35.0±7.7 years. The majority (63.4%) of the participants were midwives/nurses/medical assistants. Of the participants, 68.8% were infected by COVID-19 during the pandemic. Considering the questions addressing their level of knowledge about mpox, 44.1% of participants stated that they had never heard of this disease before. Participants were found to have mainly moderate levels of depression and anxiety and low level of stress, whereas the ratios of very severe depression and anxiety were 5.0% and 7.4%, respectively.
Conclusion: It was determined that almost half of the participants had no full knowledge of the disease before the increase in mpox cases. It was found that the participants varying levels of depression, anxiety, and stress about a new pandemic. We think that it is important to provide healthcare professionals with psychosocial support, make effort in order to determine and eliminate the sources of psychological negativities.
A Comparison of Curettage Only and Curettage with Electrocautery After Partial Matrixectomy for Ingrowing Toenail
Authors: ŞİŞMAN Ali , ÖNER Rıdvan , AVCİ Özgür , ÇEPNİ Serdar Kamil 
Published: October 2023

Aim: Ingrowing toenail is a very common disease which causes workforce losses. Although different techniques have been described in surgical treatment, one of the most frequently preferred methods is partial matrixectomy. The aim of this study was to compare the two techniques of curettage only and curettage together with electrocautery(C&E) used in addition to partial matrixectomy in ingrowing toenail surgery.
Methods: Patients who were operated for ingrown nails between 2018 and 2022 were evaluated retrospectively. Two groups were formed of 43 patients applied with curettage only and 35 patients applied with C&E. The groups were compared in respect of operating time, postoperative complications and clinical results.
Results: No significant difference was determined between the groups in respect of age, gender, affected side, classification, follow-up time, surgical duration and recovery time. Recurrence rate was higher in the curettage group (p=0.020) It occurred in 9 (20.9%) cases in the curettage group, while it occurred in 1 (2.9%) case in the C&E group. In the curettage group, the duration of erythema was observed to be significantly longer (p
Proverb Comprehension in Primary Progressive Aphasia
Authors: YAŞA İbrahim Can , KARALI Fenise Selin 
Published: October 2023

Aim: Proverb comprehension was tested in 22 patients with primary progressive aphasia utilizing idiom explanation task. The aim of this study was to determine proverb comprehension in PPA patients using the Proverb Scale.
Material and Methods: To assess the participants, Montreal Cognitive Assessment Scale, the Pyramid and Palm Trees test and the Proverb Scale were used.
Results: As a result of statistical analysis, there was a significantly difference between svPPA and lvPPA regarding idiom comprehension scores, the Pyramid and Palm Trees Test Scores and MoCA scores.
Conclusion: It is an important study to understand how the abstraction in PPA works regarding the language. In PPA subtypes, semantic memory, proverb and MoCA scores were significantly different between logopenic and semantic variants. Although MoCA and proverb comprehension were correlated in svPPA, no correlation was found in lvPPA. With similar studies in the field, it would be possible to better explain the effects of PPA, a disorder characterized by language disorders.
Clinical Outcomes of Percutaneous Endoscopic Gastrostomy in the Respiratory Intensive Care Unit
Authors: ULUÇ Kamuran , AKKÜTÜK ÖNGEL Esra , KÖYLÜ İLKAYA Nazan , DEVRAN Özkan , AY Ernur , KUTBAY ÖZÇELİK Hatice 
Published: October 2023

Aim: Percutaneous endoscopic gastrostomy (PEG) is a feeding method used in patients who are expected to require enteral nutrition for more than 2-3 weeks. We aimed to evaluate PEG indications, complications, and post-procedural patient prognosis in patients followed up in our intensive care unit and fed via PEG.
Materials and Methods: We retrospectively reviewed 51 patients receiving PEG between January 1, 2017, and December 31, 2022, in the Respiratory Intensive Care Unit.
Results: Among the patients receiving PEG, 30 (58%) were male. The average age was 63.9, ranging from 23 to 90. The mean scores for the Glasgow Coma Scale (GCS), Acute Physiology and Chronic Health Evaluation II (APACHE II), and Sepsis Related Organ Failure Assessment (SOFA) were 8.47, 22, and 7.45, respectively. The mean duration until PEG placement was 24.8 days, and the average intensive care unit (ICU) hospitalization was 48.8 days.PEG was performed in 21 patients (41.2%) due to cerebrovascular disease, in 19 patients (37.3%) due to Alzheimer, dementia, or Parkinson's disease, and 18 patients (35.3%) due to prolonged mechanical ventilation. The complication rate associated with PEG was 13.7%. Among the patients who underwent PEG, 35 (68.6%) were discharged, while 16 (31.4%) died.
Conclusion: Considering its easy use at bedside, low complication, and mortality rates, PEG insertion is appropriate for continuing enteral therapies, especially in intensive care patients with insufficient oral intake.
Comparison of Abdominal Initial Entry Techniques in Gynecological Laparoscopy
Authors: GUNDOGDU Elif , USTA Taner 
Published: October 2023

Objective: The aim of this study is to assess the safety of laparoscopic entry techniques.
Materials and Methods: Within the scope of the study, medical records of patients who underwent laparoscopy due to various gynecological indications at our clinic between January 1, 2011, and July 1, 2015, were examined. Evaluation was conducted using our hospital’s electronic database.
Results: In the patient cohort, direct trocar placement was preferred in 91.8% (1025 patients), Veress needle placement was used in 7.4% (82 patients), and an open technique was used in 0.8% (9 patients). In terms of entry sites, umbilicus was the most commonly chosen option, being preferred in 97.2% (1085 patients) of cases. In 2.4% of patients (27 patients), the midline abdominal trocar was preferred as the initial trocar insertion site. Among these patients, suprapubic incision was preferred in 62% (17 patients), while Lee-Huang point was chosen as the entry site in 38% (10 patients).Looking at the history of previous surgeries, 18.5% (206 patients) had a history of prior abdominal surgery, and 3.5% (39 patients) had undergone two previous surgical procedures. Only 0.1% (1 patient) had undergone three or more abdominal surgeries.
Discussion: In conclusion, no clear superiority of one initial entry technique over another has been proven. Despite the extensive literature on laparoscopic entry, debates regarding the most effective method to prevent significant complications continue.
The Role of Communication with the Field during the Pandemic Period: A District Intervention Example in Preventive Health Services
Authors: SEZEROL Mehmet Akif , ALTAŞ Zeynep Meva 
Published: October 2023

Aim: The aim of this study was to examine the effect of administrative meetings with family health center staff on cancer and autism screenings in a district of Istanbul.
Material and Method: The study was designed as an intervention research conducted in a district of Istanbul. The population of the study consisted of employees working in family health centers (24 family health centers) in Sultanbeyli district. The meetings were held at the end of February 2022 at the District Health Directorate building. During the meetings, the aspects that need to be improved, especially regarding cancer and autism screenings, were conveyed. Following these meetings for field staff, the changes in preventive health services (number of screenings) at the district level were analyzed. All data were analyzed retrospectively from district health directorate records.
Results: For cervical cancer screening, the total number of screenings in Sultanbeyli district in January-February and March-April were 144 and 235, respectively. For colon cancer, the total number of screenings in January-February and March-April were 54 and 277, respectively. The total number of autism screenings in January-February and March-April were 565 and 1388, respectively. Cervical cancer screenings, colon cancer screenings and autism screenings showed statistically significant increases after the meetings (p=0.002, p
Kidney health of refugee children: an ongoing challenge
Authors: TANER Sevgin , EKBERLİ Gunay 
Published: October 2023

Aim: Its geographical proximity to Syria makes Turkey an important destination and transit country for refugees from various countries. The aim of this study is to determine the kidney and urological disease profile and to reveal the ongoing problems of refugee children who applied to a single center in Adana, home to a dense refugee population. To the best of our knowledge, this study is the largest single center experience with the refugee pediatric patient population in this field.
Methods: Medical records of 614 refugee children admitted to the pediatric nephrology and urology departments between February 2020 and May 2022 evaluated retrospectively. A total of 530 patients were included in the study.
Results: Median age of the 530 patients (301 male/229 female) was 72 months. The median follow-up time was 7 months (IQR 14 months). Congenital anomalies of the kidney and urinary tract with 181 patients (34.2%) is the most common diagnosis. The frequency of chronic kidney disease (CKD) of the patients was determined as 25% with 132 patients. 64 (12%) of the patients required surgical intervention. It was observed that 322 (61%) of the patients did not come to their regular follow-ups and delayed their follow-up.
Conclusion: Irregular follow-up and delaying the treatment can lead to sad consequences in patients with CKD in the long term. We believe that regular patient follow-up will have a positive impact on the long-term follow-up results of the patients and on the health costs of the country hosting the refugee patient profile.
Evaluation of endoscopy timing in patients with acute upper gastrointestinal bleeding in emergency department
Authors: YURTSEVER Guner 
Published: October 2023

Background: Endoscopy is recommended in acute upper gastrointestinal bleeding (AUGIB) to detect the bleeding source and stop the bleeding. The optimal timing of endoscopy in AUGIB is controversial. We aimed to investigate the time of endoscopy and the factors affecting it.
Materials and methods: Retrospective, single-center study. The patients were divided into four groups: endoscopy after discharge, 0-12 hours endoscopy, 12-24 hours endoscopy and 24 hours later. Age, sex, vital signs, laboratory findings were recorded. Glasgow-Blatchford Score (GBS) and Charlson comorbidity index (CCI) were calculated. The obtained data were compared between these four groups. All-cause mortality for 30 days was recorded.
Results: A total of 318 patients were included. In the comparison of endoscopy times, the parameters found to be statistically significant between the four groups are Hb, BUN, and INR levels, GBS and CCI. As a result of CHAID analysis, the most crucial variable affecting the timing of endoscopy was found to be the Hb value of the patients (χ2=66.528; adjusted p=0.000). Mortality occurred in 10.69% of the patients. The timing of endoscopy did not affect mortality. In binary logistic regression analysis, low systolic BP (0.967 times increase), high CCI (86,402 times increase) were found to affect mortality.
Conclusion: The factors affecting the timing of endoscopy are the signs of bleeding. A thorough follow-up of vital signs in patients presenting to the emergency department with acute gastrointestinal bleeding, particularly an evaluation of systolic blood pressure and detailed questioning of additional comorbid conditions, is critical to reduce mortality.
Pseudoangiomatous stromal hyperplasia of the breast: multimodality imaging findings
Authors: GÜLDOĞAN Nilgün , ARSLAN Aydan , ÖZYILMAZ Safa , YILMAZ Ebru , TÜRK Ebru Banu , TOPAL Cumhur 
Published: October 2023

Background/Aim: Pseudoangiomatous stromal hyperplasia (PASH) is a rare benign mesenchymal proliferative breast lesion. The literature contains little information on the radiological results of this uncommon tumor. In this study, we aim to define the radiologic findings of PASH through our institutional experience.
Materials and Methods: Patients with PASH of the breast reported in the surgical database of our institution from 2020 to 2023 were retrospectively reviewed. PASH was detected in 11 female patients among the patients who underwent a total of 2172 breast tru-cut biopsies. Nine patients whose imaging studies could be recalled from the picture archiving systems (PACS) were included in the study. BI-RADS, 5th edition, was used to analyze and classify radiologic findings.
Results: The median age of cases was 41 (range 22–53). Our single-center incidence was found to be 0.5%. Considering the sonographic findings, all of the lesions had an oval shape. On mammography, they were defined as focal asymmetry or circumscribed masses. An MRI was available in three cases. All three cases were hypointense on T1-weighted sequences and hyperintense on T2-weighted sequences. They displayed type 1 or type 2 enhancement curves in the dynamic contrast-enhanced images. No diffusion restriction was detected.
Conclusion: In this study, tumor-forming PASH were generally circumscribed oval hypoechoic solid masses with minimal vascularity and no posterior acoustic features on ultrasound. On mammography, calcification, architectural distortion, or spiculation were not present in any of the cases. MRI findings were t2 hyperintensity, type 1–2 enhancement kinetics, and no diffusion restriction. In all imaging modalities, the imaging characteristics point to a benign lesion.
Comparison of Analgesic Efficacy of Cooling Spray and Saline Spray in Wrist Trauma; Randomized Controlled Double Blind Study
Authors: BİLGİN Serkan , EFGAN Mehmet Göktuğ 
Published: October 2023

Background: Cooling spray application is commonly used in sports injuries to manage acute pain and reduce tissue edema. However, its effectiveness in treating acute trauma in the emergency department remains understudied. This prospective randomized controlled trial assessed the efficacy of cooling spray for pain management in patients with wrist injuries.
Methods: A randomized trial was conducted in a tertiary care hospital's trauma department. Patients with wrist trauma were assigned to cooling spray or placebo (saline spray) groups. Cooling spray was Cryos®Spray (Phyto Performance, Italy), while placebo was chilled saline in an identical bottle. Pain scores and radiographic images were evaluated.

Results: In 131 patients (mean age: 35.60±19.58 years, 26.7% fractures), cooling spray (n=73) yielded a delta pain score of 1.74±1.88, while saline (n=58) had 0.84±1.54 (p=0.003). For fracture patients, cooling spray's delta score was 2.26±1.88, compared to saline's 0.0±0.96 (
Evaluation of the quality and reliability of YouTube videos on premature ventricular contraction
Authors: GÖÇER Kemal 
Published: October 2023

Aim:
The internet is a popular and continually utilized platform to gain medical knowledge for patients and health professionals. This research aimed to evaluate the accuracy and quality of videos for premature ventricular contraction (PVC) on YouTube.
Material and method: The keyword "premature ventricular contraction" was inputted into the YouTube search engine. The 60 most watched videos on YouTube were analyzed. Six of these were excluded from the study. A total of 54 patients were included in the study. General characteristics of the videos were recorded. Two specialist physicians reviewed all videos. GQS, DISCERN, and JAMA scoring systems were used to test the video quality and reliability. Video quality was divided into three groups according to the GQS score. Video characteristics were compared between quality groups.
Results: 37% of the videos posted were from doctors, and the most frequently seen content was related to general information about PVCs, accounting for 70.4%. There were 24 high-quality videos. The number of video comments (p=0.006), daily view rate (p=0.001), JAMA (p=