bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors for Herpes Zoster infections– a systematic review and meta-analysis unveiling common trends and heterogeneity patterns
Authors: Steinmann Maren , Lampe David , Grosser John , Schmidt Juliana , Hohoff Marla-Louise , Fischer Anita , Greiner Wolfgang 
Published: October 2023

Abstract
Purpose:
The burden of herpes zoster (HZ) is substantial and numerous chronic underlying conditions are known as predisposing risk factors for HZ onset. Thus, a comprehensive study is needed to synthesize existing evidence. This study aims to comprehensively identify these risk factors.
Methods:
A systematic literature search was done using MEDLINE via PubMed, EMBASE and Web of Science for studies published from January 1, 2003-January 1, 2023. Eligible studies were case-control or cohort studies. A random-effects model and multiple meta-regression were used to summarize the odds ratios (OR) with a 95% confidence interval (CI). Heterogeneity was analyzed with influence analyses.
Results:
Of 6,392 considered records, 80 were included in the meta-analysis. 21 different conditions were identified as potential risk factors for HZ. Transplantation was associated with the highest risk for HZ with a pooled OR = 4.51 (95% CI [1.9–10.7]). Other risk factors ranged from OR = 1.17–2.87, indicating an increased risk for all underlying conditions included in these analyses. Heterogeneity was substantial in all provided analyses. Sensitivity analyses showed comparable results regarding the pooled effect estimates and heterogeneity.
Conclusions:
We identified 21 potential risk factors: asthma, autoimmune disorders, cancer, cardiovascular disorders, chronic heart failure (CHF), COPD, depression, diabetes, digestive disorders, endocrine and metabolic disorders, hematological disorders, HIV, inflammatory bowel disease (IBD), mental health conditions, musculoskeletal disorders, neurological disorders, psoriasis, renal disorders, rheumatoid arthritis (RA), systemic lupus erythematosus (SLE) and transplantation. This study showed an increased risk for HZ infections for all identified factors.
Growth Performance, Enzymatic Activities, Haematology and Serum Biochemistry of Clarias Gariepinus Fed Thermally Processed Jatropha Curcas Kernel Meal Based Diets
Authors: Jimoh Jeremiah Olanipekun , Omitoyin Bamidele Oluwarotimi , Ajani Emmanuel Kolawole , Liew Hon Jung , Rahmah Sharifah , Okomoda Victor Tosin , Mohamad Siti Jalilah , Omobepade Bayode Paul , Ola Lidya , Fabusoro Abiola Ayodeji , Olasunkanmi John Bunmi , Ayegba Emmanuel Omachi 
Published: October 2023

Abstract

Jatropha curcaskernel meal is an agro-industrial by-product that is rich in essential nutrients that can be utilized by fish for optimal growth. The toxic substance and anti-nutritional factors (ANFs) must be removed to unlock its dietary potential. This study attempted to reduce the ANFs and improve the nutritional quality ofJ. curcasusing autoclaving while the end product was used to replace soybean meal at 25%, 50%, 75% and 100% (TTR25, TTR50, TTR75 and TTR100 respectively) with the control (SBM) in prepared diets (40% CP) ofClarias gariepinusjuveniles (n = 150, average initial weight = 18.21g). The results showed that thermal treatment reduced significantly the phorbol ester and other ANFs contents inJ. curcasmeal. However, the changes in the proximate compositions save for lipid content were insignificant. Further results after 63 days feeding trial showed that fish fed 25% (TTR25)J. curcashad the best weight gain (111.99 ± 14.53), feed conversion ratio (1.11 ± 0.16), protein efficiency ratio (1.41 ± 0.22) and survival rate (86.67 ± 11.55). Similar results were obtained in haematology, serum biochemistry and protease activity analysis with TTR25 fish emerging with the best results. However, the amylase and lipase activity results revealed that TTR75 and SBM fish had the best activities respectively. However, the results were not significantly different from that of TTR25. It is therefore concluded thatJ. curcaskernel meal can be rid of toxic substances and anti-nutrients through autoclaving while 25% replacement of soybeans withJ. curcaskernel meal is recommended in the diet ofClarias gariepinusjuveniles.
Animal supplementation and forage legume in an integrated crop-livestock systems: nitrogen export by animals, cycling, and soybean productivity
Authors: Danna Mirella , Scheeren Fernanda , Sartor Laercio Ricardo , Menezes Luis Fernando Glasenapp , Paris Wagner , Andriotti Nathalia , Garrett Caio Emanuell 
Published: October 2023

Abstract
Animal supplementation and grass-legume mixture can increase the stocking rate and crop and animal waste in the soil. Our hypothesis is that these alternatives can increase the amount of nitrogen recycled in an integrated crop-livestock system. We analyzed in an integrated crop­livestock system, whether the nitrogen recycling and the soybean crops are influenced by legume and animal supplementation (1% live weight) in beef cattle production. We evaluated animal nitrogen intake, the recycled through feces and urine, and the amount of nitrogen retained in beef cattle carcass. In summer, the rate of dry matter, and nutrient release from the residual biomass after grazing and feces of animals, the export of nitrogen by soybean crops, and grain production. It was possible to increase the stocking rate in 21% through supplementation and with this there was a 33% increase in the return of nitrogen through feces and urine compared to the control. This result interfered with the export of nitrogen in grains, which was 9% higher in paddocks where there was animal supplementation. The amount of nitrogen exporting by the animals, in 90 days of grazing, did not differ between treatments, averaging 8.18 kg ha− 1 of N. Nitrogen return in a complete cycle increased by 19%, where animal and legume supplementation was used. We concluded that the supplementation and use of legumes are alternatives to increase the nitrogen recycled in integrated farming systems. Of the total N exporting, about 3 to 4% are through animals, and 96 to 97% are through soybean grains.
Long-Term Surgical Outcomes of Pediatric Retinal Detachment Associated with Congenital Glaucoma
Authors: Artunay Ozgur , Ozbek Merve 
Published: October 2023

Abstract
Purpose
Congenital glaucoma (CG) is an extremely rare disease with an incidence of one in 10,000 live births. Increasing axial length due to CG predisposes to retinal thinning and retinal detachment (RD). The aim of the present study is to determine the long-term surgical outcomes of pediatric RD associated with CG.
Methods
This was a retrospective study including pediatric patients who underwent vitrectomy with silicone oil injection for RD associated with CG. Ocular examination reports and surgical findings of patients were analyzed to assess for the anatomical and functional outcomes of the surgery.
Results
The study included 20 eyes of 20 children. Mean age was 10.35 ± 3.73 years, range 5–16 years. Mean axial length was 26.10 ± 2.19 mm (range, 20.31–28.91 mm). In 11 eyes, the intraocular pressure was < 6 mmHg at the time of RD diagnosis. The mean logarithm of the minimum angle of resolution (logMAR) visual acuity improved from 2.13 ± 0.45 to 2.02 ± 0.61 (p = 0.477) after surgery. Mean follow-up period was 24.55 ± 10.01 months, range 12–48 months. During the follow-up period, 6 patients (30%) had revision of surgery due to recurrent RD. Globe survival has been achieved in 19 out of 20 eyes (95%).
Conclusion
Ocular comorbidities play a significant role in limiting final visual outcomes. Despite the poor visual prognosis of surgery, globe survival can achieve in such cases. Globe preservation has an important impact on patients’ quality of life, psychological and social functionality. Moreover, ambulatory vision can be preserved in most eyes.
The Value of Multimodal Treatment in Anaplastic Thyroid Cancer Patients with Distant Metastasis
Authors: Guo Hongen , Lin Hanqing 
Published: October 2023

Abstract
Background
Anaplastic thyroid cancer (ATC) is a rare and aggressive malignancy with a poor prognosis, particularly in patients presenting with distant metastasis (DM). This study aimed to assess the effect of combination treatment strategies on survival in ATC patients with DM.
Methods
A retrospective analysis was conducted using data from the Surveillance, Epidemiology, and End Results (SEER) database to identify primary ATC cases with DM at diagnosis. Univariate and multivariate Cox proportional hazards regression analyses were performed to identify independent risk factors for survival.
Results
Of the 315 ATC patients with DM included in the study, surgery to the primary tumor, radiotherapy, chemotherapy, and lung metastasis were identified as independent risk factors for survival. Patients who received primary tumor surgery plus chemotherapy or surgery plus chemoradiation exhibited a superior outcome compared to those who received only one treatment modality.
Conclusion
Our findings suggest that a combination treatment approach, particularly surgery combined with radiotherapy or surgery combined with chemoradiotherapy, may provide the most optimal treatment option for ATC patients with DM. These results may inform clinical decision-making and improve patient outcomes in this challenging disease setting.
Trends in Worldwide research on laser in ophthalmology over the period 1990-2022: A bibliometric study of hotspots, nodes, bursts, and trends
Authors: Jiang Yaping , Cai Yuying , Zhang Xin , Chen Li , Zhou Xingtao , Chen Yihui 
Published: October 2023

Abstract
Background
Laser therapy has been proven as an effective technique for managing ophthalmological disorders. To guide future research, we conducted a bibliometric analysis of laser applications in eye diseases from 1990 to 2022, aiming to identify key themes and trends.
Methods
we retrieved 3027 publications from the Web of Science Core Collection (WoSCC). Bibliometrix was used for science mapping of the literature, while VOSviewer and CiteSpace were applied to visualize co-authorship, co-citation, co-occurrence, and bibliographic coupling networks.
Results
From a co-citation reference network, we identified 52 distinct clusters. Our analysis uncovered three main research trends. The first trend revolves around the potential evolution of corneal laser surgery techniques, shifting from the treatment of refractive errors to broader applications in biomedical optics. The second trend illustrates the advancement of laser applications in treating a range of disorders, from retinal and ocular surface diseases to glaucoma. The third trend focuses on the innovative uses of established technologies.
Conclusions
This study offers significant insights into the evolution of laser applications in ophthalmology over the past 30 years, which will undoubtedly assist scientists in directing further research in this promising field.
Diabetic Foot Care and Screening Practices among Iranian Nursing Students: A Cross-Sectional Survey in Teaching Hospitals of Tabriz
Authors: Moghadam Aylar , Attari Ahmad Mirza Aghazadeh , Zamanzadeh Vahid , Lotfi Mojgan 
Published: October 2023

Abstract
Background Diabetic foot ulcers (DFUs) are a serious complication of diabetes that can lead to amputation and reduced quality of life. Nurses play a vital role in preventing and managing DFUs by educating, assessing, and caring for diabetic patients. Nursing students, as future health care providers, need to have adequate knowledge, attitudes, and practices regarding diabetic foot care and screening. However, there is a lack of studies on these factors among nursing students in Iran.Methods This was a cross-sectional study conducted in 2022. The sample consisted of 200 nursing students from the Tabriz Faculty of Nursing and Midwifery. Data were collected using a questionnaire that included demographic and occupational characteristics, a knowledge questionnaire, an attitude questionnaire, and a diabetic foot screening checklist. Data were analyzed using SPSS 22 software.Results The results showed that approximately 55% of the students had relatively good knowledge, 49% had a positive attitude, and 7.5% had very good practices regarding diabetic foot care and screening. However, more than half of the students had poor knowledge or practice, and some of them considered diabetic foot care to be time-consuming.Conclusion The findings of this study revealed that the nursing students had received previous education about diabetic foot care management, but their knowledge and practice were still inadequate. Their attitude was generally positive, but some barriers existed for translating it into clinical practice. These results suggest that there is a need to improve the curriculum and training methods for nursing students regarding diabetic foot care management and screening. This can enhance their competence and confidence in providing quality care to diabetic patients and preventing DFUs and amputations.
RELAÇÕES SERES HUMANOS-NATUREZA: TRABALHO, CULTURA E PRODUÇÃO DE SABERES
Authors: Bueno Fischer Maria Clara , Rodrigues Doriedson do Socorro 
Published: October 2023

O presente texto traz, a partir do materialismo histórico-dialético, uma contribuição à análise do intercâmbio seres humanos-natureza mediados pelo trabalho como crítica do modo de produção capitalista, que impõe uma ruptura dessa relação nesse intercâmbio. Contudo, contrapondo-se a essa perspectiva, é possível identificar outros modos de vida que resistem a isso no interior das contradições capital-trabalho. As reflexões propostas almejam colaborar com o aprofundamento de análises sobre as relações entre trabalho e educação, em particular o trabalho como princípio educativo, a partir do enfoque do tema relações entre seres humanos e natureza.

Palavras-chave: Relações entre seres humanos-natureza. Trabalho como princípio educativo. Modos de vida. Povos e comunidades tradicionais.
Wahania sezonowe zjawisk ekonomiczno-społecznych na obszarze województwa lubuskiego
Authors: Szczuciński Przemysław 
Published: October 2023

Artykuł ma charakter opisowo-poznawczy. Podjęto w nim próbę scharakteryzowania wahań sezonowych wybranych zjawisk ekonomiczno-społecznych w województwie lubuskim. Z wykorzystaniem metody Census I dokonano dekompozycji sezonowej szeregów czasowych produkcji sprzedanej przemysłu, liczby bezrobotnych, liczby turystów korzystających z bazy noclegowej oraz liczby zdarzeń drogowych w regionie. Analizowano dane statystyczne o miesięcznej częstotliwości za okres 2007-2022. Wyniki badań dowodzą, że wymienione zjawiska pozostają w regionie pod istotnym wpływem czynników sezonowych.
Sustainable Leadership And Learning Organization Relationship in Schools: A Mixed Method Research
Authors: DAĞDEVİREN ERTAŞ Behiye , ÖZDEMİR Murat 
Published: October 2023

Purpose: The purpose of this research is to determine, according to the views of primary school teacher, the sustainable leadership behaviors of school principals and the relationship between sustainable leadership and the formation of schools as learning organizations.
Methodology: This study aimed to determine the relationship between the sustainable leadership behaviors of school principals and the formation of schools as learning organizations in public primary schools located in Yozgat, Turkey. A mixed- methods approach, was employed in the study, which utilized both quantitative and qualitative methods. The quantitative portion of the study utilized a "predictive correlational design," while the qualitative portion utilized a "phenomenological design" to examine the research question.
Findings: The research findings indicate that school principals exhibit high levels of sustainable leadership behavior based on the average scores given by teachers. In terms of dimensions, the highest average scores were obtained for deep learning. According to teachers opinions, the average scores for a learning organization were also found to be high. The highest average score in terms of dimensions was for team learning. A positive relationship was discovered between sustainable leadership and organizational learning. Qualitative results indicated that school principals who scored high in all dimensions of sustainable leadership provided more answers. Similarly, when examining qualitative results related to organizational learning, it was discovered that school principals who scored high in all dimensions of sustainable leadership also provided more answers.
Highlights: The literature on sustainable leadership in educational organizations is very limited. Therefore, sustainable leadership perceptions in educational organizations can be examined by considering different concepts together. The relationships between these concepts and their impact can also be examined. Based on the views of primary school teachers, this study suggests that sustainable leadership has an impact on the learning organization. New studies can be conducted on other samples to compare the results of this study, and to investigate the impact of sustainable leadership on educational organizations further.
Critical Factors of Sustainable Development in Road Management
Authors: Němec Miroslav 
Published: October 2023

AbstractA focus on changing practices towards greater use of environmentally friendly practices in all activities related to the maintenance of the assets and buildings entrusted to the Road Administration and Maintenance logically entails increased financial requirements. As this is a relatively complex issue, road management must be understood in a holistic way, including risk assessment. The dynamics of the sector entails a considerable number of critical factors that have a direct or indirect impact on the achievement of the basic goals of infrastructure management and maintenance organization in the context of ensuring road management and mobility while respecting the basic concept of sustainability. The objective of this article is to define the critical factors of sustainable development in road management, especially in terms of ad hoc maintenance.
Analyzing serum tryptophan metabolites in patients with gestational diabetes mellitus
Authors: Özdemir Muammer , Abusoglu Sedat , Baldane Suleyman , Kıraç Cem Onur , Unlu Ali , Onmaz Duygu Eryavuz , Çelik Murat , Abusoglu Gulsum 
Published: October 2023

Abstract

Introduction: Although pregnancy is a physiological condition, the secretion of diabetogenic hormones such as growth hormone, corticotropin-releasing hormone, placental lactogen hormone, prolactin and progesterone from the placenta could lead to insulin resistance (IR). In Metabolic Syndrome, obesity and Type1&2 diabetes, a shift in the kynurenine pathway (KP) towards IDO activation is observed. The activation of the IDO leads to the activation of the Aryl hydrocarbon receptor (AhR) and Interleukin-6 (IL-6) also, which may also induce some effects like insulin resistance, β-cell disfunction and increased gluconeogenesis. We hypothesized that the overactivation of IDO and some KP enzymes would be observed in GDM patients, in a similar manner to metabolic syndrome, prediabetes, and diabetes patients.

Methods: 50 patients and 50 controls, who applied to the Endocrinology outpatient clinic of Selcuk University Faculty of Medicine were included. Serum triptophan metabolite levels were measured with liquid chromatography tandem mass spectrometry.

Results: Tryptophan and KYNA values was found to be lower in the patient group diagnosed with GDM (p<0.001 and p<0.001, respectively). The levels of KYN, 3-OH AA, 3-OH-KYN and KTR were significantly higher in the patient group compared to the control group (p=0.008, p<0.001, p=0.05 and p<0.001, respectively).

Conclusions: Understanding the changes that occur in this pathway in GDM patients may provide insight into the development of the disease. Also these tests could be used as supplementary tests in gestational diabetes, which could assist in diagnosis and patient follow-up.
Selection of suitable reference genes for miRNA expression normalization by quantitative RTPCR under abiotic stress in Larix olgensis
Authors: Zhang Sufang , Yan Shanshan , Yan Pingyu , Zhang Li , Zhang Hanguo , Zhang Lei 
Published: October 2023

Abstract
Suitable selection of endogenous controls is necessity for obtaining reliable qRT-PCR results. However, insufficient attention has been paid to the selection of endogenous controls for normalization in different stresses in plant, especially Larix olgensis. In this study, we screened candidate internal reference genes for miRNA expression normalization after subjecting Larix olgensis PEG-induced drought, NaHCO3, or NaCl stress. Needles samples were collected at 0, 12, 24, 48 and 96 h after treatment. Four common housekeeping genes and 11 mature miRNAs that were found to be stably expressed in small RNA sequencing data of Larix olgensis were selected as candidate internal reference genes. Their expression levels were assessed by qRT-PCR. GeNorm and NormFinder were used to analyse the stability of gene expression from the candidate internal reference genes. Finally, the expression of some miRNAs was analysed after stress. The results showed that miRNAs exhibited better expression stability compared to the analysed ncRNAs. Under PEG, NaHCO3, or NaCl stress, miR83321, miR43169, and miR74940 were identified as the most suitable internal reference genes, respectively. Under PEG stress, the expression of most miRNAs reached its highest level at 12 h, showing a trend of first increasing expression and then decreasing. Similarly, under NaHCO3 and NaCl stress, the expression of most miRNAs reached its maximum levels at 48 h and 12 h, respectively. This indicates that most miRNAs more quickly respond to PEG and NaCl stress than NaHCO3 stress.
Cumhuriyetin 2. Yüzyılına Girerken Yatırımlarla İlgili Çoklu Yapıda Kalkınma Ajansı Modelinin Türkiye’deki Geleceği
Authors: KÜÇÜKYAĞCI Nazmi 
Published: October 2023

Küreselleşmenin hız kazandığı günümüz dünyasında ülkeler birbirleriyle sürekli bir rekabet içerisindedir. Bu rekabette her ülke daha çok yatırım çekerek ulusal gelirini ve halkın refah düzeyini artırma arayışındadır. Bu minvalde bölge kalkınma ajanslarının ilk örneği 1933 yılında ABD’de ortaya çıkmış ve daha sonra Avrupa Birliği (AB) ile AB’ye aday ülkelerde kurulmuştur. Bölge kalkınma ajansları; kapsamında yer alan kentlerin veya bölgelerin kalkınmasını sağlamak, yatırım bakımından ulusal ve uluslararası çekiciliğini artırmak, kültürel ve sosyal değerlerini muhafaza etmek ve geliştirme amacıyla kurulmaktadır.
Bölge kalkınma ajanslarının yereldeki aktörler olan kamu-özel ve sivil toplum kuruluşları arasındaki iş birliği ve koordinasyonu geliştireceği, gerek ulusal gerekse de uluslararası kaynaklara dayalı olarak bölgesel düzeyde kalkınmayı sağlayacağı, yerel düzeyde inovasyon ve planlama ile bölgesel kalkınmaya katkıda bulunacağı ve katılımcı demokrasi ve yönetişim anlayışını bölgesel düzeyde hayata geçireceği öngörülmektedir. Bu kapsamda Türkiye’de 2000’li yılların ilk on yılında sürdürülebilir kalkınmayı sağlamak, bölgesel ve yerel potansiyeli harekete geçirmeye yönelik kurulan yegâne yapılardan biri kalkınma ajansları olmuştur. Bu çalışmada kuruluşlarından itibaren on beş yıllık zaman geçen kalkınma ajanslarının kuruluş süreci, coğrafi sınırlara uygunluğu, kurumsal yapıları, görev, yetki ve sorumlulukları ile bütçe analizleri çerçevesinde etkinlik ve verimlilikleri ele alınarak bu modelin yatırımlarla ilgili diğer kurumlar arasındaki yeri tartışılmaktadır. Cumhuriyetin ikinci yüzyılına girerken bu modelin Türkiye’deki başarılı ve başarısız yönleri üzerinde durulmakta ve gelecek dönemde kalkınma ajanslarının kalıcı bir yapı olarak varlığını sürdürüp sürdüremeyeceği ve yatırımlarla ilgili çoklu yapının olduğu düzende bu modelin hangi yöne evirilebileceği değerlendirilmektedir.