bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of digitization of scientific information on the scholarly communication of scientists. Sponsored by SIG TI, DL
Authors: Anderson Cokie , Bremholm Tony , Hemminger Bradley , Brown Cecelia , Vaughan K. T. 
Published: January 2005

AbstractThe possibility of a freely accessible universal open archive containing all scholarly material is quickly becoming a reality. This is especially the case for scientific information where the increase in openly available scientific material, such as e‐prints, e‐journals, as well as genetic sequences, experimental results, and statistical analyses is beyond that believed imaginable a decade ago. Not only is an array of scientific information available on the Internet as soon as it is created, but older information, as well as less mainstream information, is also being mounted on the Internet for the benefit of the global scientific community. In order to be useful, however, electronically archived materials must first be digitized and then classified and indexed in order for scientists to retrieve the information quickly and easily. How this is accomplished has a direct impact on the ways in which scientists work and communicate. The panelists in this session will discuss current research on the challenges and solutions for the digitization of scientific information employing adaptations to XML. Also a project describing how a variety of digital scientific objects can be stored and retrieved using a single generic framework based on the Open Archives Initiative standards and Dublin Core metadata will be presented. Additionally the effects of digitization on the influence of a small state scientific association's proceedings upon the communication of scientific ideas to the wider scientific community will be discussed. Lastly, a panelist will describe a project exploring the use and usability of bioinformatics databases. The panelists' insights will provide both a behind the scenes and a front stage view of the creation, management, and use of freely available electronic scientific information.
Humanizing information retrieval: Organizing “works.” Sponsored by SIG CR
Authors: Smiraglia Richard P. , Carlyle Allyson , O'Neill Edward T. , LeBoeuf Patrick , Coleman Anita 
Published: January 2005

AbstractThe purpose of this panel is to explore our understanding of the “work” entity and its role in information retrieval. In the past, works have been discussed in the context of bibliographic control, or more narrowly in the context of the library catalog. But as research into the nature of works has matured over the past decade or so, we have begun to broaden the basic definitions of the components of the work‐relationship, the better to view the problem of works from an information retrieval perspective.A work, at a basic level, is a deliberately created knowledge‐record (i.e. a text, and oeuvre, etc.) representing a coordinated set of ideas (i.e., ideational content) that is conveyed with the purpose of being communicated to a consumer. A document may contain one or more works, and a work may exist on one or more documents.Quite frequently, as it turns out, a given work exists in many instantiations, which means it appears on many different documents, which presents an interesting problem for information retrieval. Research into the nature of the work entity points to an evolving research front.
What can we learn from usage data? Sponsored by SIG USE
Authors: Shim Wonsik , Connaway Lynn Silipigni , Tenopir Carol , Wang Peiling , Zhang Dongming 
Published: January 2005

AbstractThe move to a networked environment has significantly increased the range of services and resources available to users, especially at institutions of higher education. The need to know the extent of use and usage patterns, coupled with the availability of machine‐generated usage measures has created opportunities for research on many fronts. This panel brings together researchers and practitioners to share information on completed and on‐going projects and to discuss issues related to collecting, analyzing and making use of usage statistics generated from the use of electronic materials such as e‐journals, e‐books, and various other digital information resources.
3D images: From theory to applications. Sponsored by SIG VIS
Authors: Hastings Samantha , Lewis Elise , Ozeren Shuleyman , Roy Paul , McDonald Bill 
Published: January 2005

AbstractThe use of 3D images as information bearing objects is rapidly becoming part of the next generation of web applications. From museums to criminal investigations, the 3D image is proving to be a powerful method of simulation for modeling objects and providing interfaces for deep data repositories. The panelists will describe current advances in 3D imaging technologies and demonstrate new applications. Projects presented include: User Preferences in 3D Image Manipulations, Use of 3D Space to Model Crime Scene Information, Museums and 3D Images.
The bibliomining process: Data warehousing and data mining for libraries. Sponsored by SIG LT
Authors: Nicholson Scott , Hwang San‐Yih , Keezer Paula , O'Neill Edward T. 
Published: January 2005

AbstractBibliomining is the combination of data mining, bibliometrics, statistics, and reporting tools used to extract patterns of behavior‐based artifacts and item‐based metadata from library systems. The bibliomining process involves the identification of problem areas, the collecting and anonymizing of data into a data warehouse, the exploration of the data with data mining tools, and the analysis, validation, and implementation of the results. This panel will introduce the topic of bibliomining and present ways in which data warehousing and data mining are currently being used in library settings.
Social network analysis and citation network analysis: Complementary approaches to the study of scientific communication. Sponsored by SIG MET
Authors: Marion Linda S. , Garfield Eugene , Hargens Lowell L. , Lievrouw Leah A. , White Howard D. , Wilson Concepción S. 
Published: January 2005

AbstractThe study of networks is gaining prominence in many disciplines as well as in the popular press. Information scientists, however, have studied networks for decades. This session will explore the potential of using citation network analysis and social network analysis to provide structural assessments of scientific communication. Panelists will discuss their research and highlight the advantages and challenges of using these methods to derive a comprehensive portrait of the diffusion of scientific knowledge.
Classification across disciplines: The same, only different. Sponsored by SIG CR, STI, MED, HFIS
Authors: Kwasnik Barbara , Miksa Francis L. , Crabbe David 
Published: January 2005

AbstractThis session seeks to bridge the recognized gap between information science understandings of classification and the applications of classification techniques in various disciplines and the corporate world. Classification experts in the information sciences are challenged to look at classification from several perspectives: how do we serve different disciplines in the arts and sciences, whose discourse traditions vary?; what can we learn from the understandings of classification as it is used implicitly and explicitly to organize information in other fields?; and, from a corporate case, on the way an artificial intelligence technology approaches the problem of knowledge representation and classification.
Architecture for access: Multimedia digital libraries and museum applications. Sponsored by SIG DL
Authors: Goodrum Abby , Hastings Samantha , Kravchyna Vika , Terrell Tom , Yayla Ahmet 
Published: January 2005

AbstractDigital libraries have extended access to many types of collections from all points of the globe. These collections include film and video archives, news material, oral histories, museum images and digitized special collections. As more multimedia collections are digitized, there is a growing need for proactive digital design to assure access and interoperability without compromising the content of the collections. Subject areas range from digital image reference services; museums and web‐based exhibits to the use of face recognition software for national security. This interactive panel session features experts who are pushing the envelope of multimedia digital libraries, from lessons learned on recent projects to architecture considerations for future standards.
The impact of HIPAA on the development of Electronic Medical Record Systems. Sponsored by SIG CR, DL, HCI
Authors: Ramachandran Hari , Obilisetty Sridhar , Bajaj Sanjay 
Published: January 2005

AbstractHIPAA, the Health Insurance Portability and Accountability Act of 1996 states that all healthcare providers must ensure the protection of patient privacy with HIPAA compliance required by April 14, 2003. The other key provision of HIPAA is portability of information and patient access. Compliance with this act may prove a major challenge due to the lack of standardization in existing systems across the industry. This panel will review the impact of the HIPAA compliance on the development of Hospital Information Systems and the ongoing challenges associated with the development of Electronic Medical Records Systems. The topics will include:

Guidelines for EMR System Selection Process with HIPAA in mind
General Issues Interpretation and Integration of HIPAA Rules Integrated Policies and Procedures Staffing Issues Employee Training
Solutions for implementing a HIPAA compliant EMR

A case study of the implementation of a EMR system using VIANETA technology will be presented.
The use of subjective attributes in personal information management systems ‐ Initial results
Authors: Bergman Ofer , Nachmias Rafi , Beyth‐Marom Ruth 
Published: January 2005

AbstractPersonal computers often serve as Personal Information Management (PIM) systems: they allow people to collect items of information and store them outside their cognitive system. Research has consistently shown that users of PIM systems find it hard to remember where they placed their personal information and thus have difficulties in retrieving it. A possible explanation for these difficulties is that PIM system designers are not sensitive enough to the fact that it is a personal system: the same person that stores the information is the one who retrieves it. In a recent article we suggested a user‐subjective approach to PIM system design which advocates that PIM systems should relate to the subjective attributes that the user gives to the data stored in the PIM system. This paper presents preliminary results from a study in which users of personal computers were asked to guide the researcher in their PIM system. The study allows us to test the user‐subjective approach advocated in the mentioned article.
Rituximab treatment of an IgM monoclonal autonomic and sensory neuropathy
Authors: Goldfarb Adina R. , Weimer Louis H. , Brannagan Thomas H. 
Published: January 2005

AbstractRituximab, a monoclonal antibody against B‐cell membrane marker CD‐20, is an effective treatment for immunoglobulin M (IgM) monoclonal anti–myelin‐associated glycoprotein (MAG) neuropathies. We report a patient with an autonomic and painful sensory neuropathy associated with an IgM lambda monoclonal gammopathy, responsive to rituximab. Treatment resulted in a decline in total IgM and improvement in the patient's painful neuropathy and dysautonomia. Rituximab may be an effective and tolerable treatment for autonomic and sensory neuropathy associated with IgM monoclonal gammopathy. Muscle Nerve, 2005
Presynaptic effects of immunoglobulin G from patients with Lambert–Eaton myasthenic syndrome: Their neutralization by intravenous immunoglobulins
Authors: Buchwald Brigitte , Ahangari Raheleh , Weishaupt Andreas , Toyka Klaus V. 
Published: January 2005

AbstractIntravenous immunoglobulin (IVIg) treatment improves muscle strength in Lambert–Eaton myasthenic syndrome (LEMS), but its specific mode of action is unknown. We have delineated its mode of action on neuromuscular blocking properties of LEMS IgG. The effect of sera and purified IgG from six patients with LEMS on evoked quantal release was investigated after direct application to the motor nerve terminal by the perfused macro‐patch‐clamp electrode in mouse hemidiaphragms. The effect of LEMS IgG was analyzed alone and after coincubation with different concentrations of IVIg or its Fab fragments. All LEMS sera and purified LEMS IgG fractions taken before IVIg treatment inhibited evoked quantal release in a dose‐dependent manner. When LEMS IgG was coincubated with a therapeutic IVIg preparation, presynaptic inhibitory activity of LEMS IgG was diminished in a dose‐dependent fashion. Monovalent Fab fragments were as effective in neutralizing the activity of LEMS IgG as whole IVIg. These direct neutralizing effects of IVIg may explain its therapeutic efficacy. Muscle Nerve, 2005
Motor unit number estimates in the tibialis anterior muscle of young, old, and very old men
Authors: McNeil Chris J. , Doherty Timothy J. , Stashuk Daniel W. , Rice Charles L. 
Published: January 2005

AbstractThe rate of motor unit (MU) loss and its influence on the progression of sarcopenia is not well understood. Therefore, the main purpose of this study was to estimate and compare numbers of MUs in the tibialis anterior (TA) of young men (∼25 years) and two groups of older men (∼65 years and ≥80 years). Decomposition‐enhanced spike‐triggered averaging was used to collect surface and intramuscular electromyographic signals during isometric dorsiflexions at 25% of maximum voluntary contraction. The mean surface‐MU potential size was divided into the maximum M wave to calculate the motor unit number estimate (MUNE). The MUNE was significantly reduced in the old (91) compared to young (150) men, and further reduced in the very old men (59). Despite the smaller MUNE at age 65, strength was not reduced until beyond 80 years. This suggests that age‐related MU loss in the TA does not limit function until a critical threshold is reached. Muscle Nerve, 2005
Neuromuscular adaptations to spaceflight are specific to postural muscles
Authors: Deschenes Michael R. , Wilson Meredith H. , Kraemer William J. 
Published: January 2005

AbstractThe effects of microgravity were determined in muscles of differing function and myofiber‐type composition. Rats were assigned either to a 10‐day spaceflight mission or to ground‐based control conditions. Following the experimental period, hindlimb muscles were obtained from both groups. Cytofluorescent techniques were used to examine neuromuscular junctions (NMJs) from both slow‐ and fast‐twitch fibers. Histochemical procedures were employed to assess myofiber profiles (size and type). Results indicate that microgravity did not alter NMJ structure or myofiber profile in the tibialis anterior, a predominantly fast‐twitch, nonpostural muscle. Similarly, the NMJs and myofibers of deep regions of the gastrocnemius, a locomotor muscle possessing a mixed fiber population, were unaffected by spaceflight. In contrast, both myofibers and NMJs of the soleus—a postural muscle—demonstrated significant (P < 0.05) plasticity following exposure to spaceflight. Moreover, NMJs of both fast‐ and slow‐twitch myofibers displayed similar remodeling in that muscle. Our findings suggest that the deleterious effects of microgravity are most apparent among postural muscles, and are manifested both in myofibers and their synapses. Muscle Nerve, 2005
Synthesis of polyether‐based polyurethane‐silica nanocomposites with high elongation property
Authors: Lee Sung‐Il , Hahn Yoon Bong , Nahm Kee Suk , Lee Youn‐Sik 
Published: January 2005

AbstractThe NCO‐terminated prepolymers, prepared by reacting a mixture of poly(tetramethylene glycol) and fumed nanosilica with 4,4′‐diphenylmethane diisocyanate, were chain‐extended with 1,4‐ butanediol to yield polyurethane‐silica nanocomposites. The nanosilica particles were well dispersed in the polyurethane matrix up to 3 wt%. The polyurethane chains in the interfaces were covalently linked to the nanosilica surfaces through urethane bonds. Introduction of the nanosilica into the polyurethane enhanced both tensile strength and elongation of the resulting nanocomposite films. Especially, the elongation at break of the nanocomposite films containing 1 wt% nanosilica was 3.5 times greater than that of the pure polyurethane films. Copyright © 2005 John Wiley & Sons, Ltd.
Effects of cell structure and density on the properties of high performance polyimide foams
Authors: Williams Martha K. , Weiser Erik S. , Fesmire James E. , Grimsley Brian W. , Smith Trent M. , Brenner James R. , Nelson Gordon L. 
Published: January 2005

AbstractActivity at the NASA Langley Research Center (LaRC) has focused on developing low density polyimide foam and foam structures which are made using monomeric solutions or salt solutions formed from the reaction of a dianhydride and diamine dissolved in a mixture of foaming agents and alkyl alcohol at room temperature. Monomer blends may be used to make a variety of polyimide foams with varying properties. The first foaming process developed consisted of thermal cycling the polymer precursor residuum and allowing the inflation of the particles to interact to create the foam. This process has resulted in foam structures with higher percentages of open cell content. Another innovative foaming process has been developed that begins with partially inflated microspheres, “friable balloons”, with incomplete polymer molecular weight gain, which when fully cured into a foam results in more closed cell structures.In a research study performed by NASA Kennedy Space Center (KSC) and LaRC, two closely related polyimide foams, TEEK‐H series and TEEK‐L series, (4,4′‐oxydiphthalic anhydride/3,4′‐oxydianiline and 3,3′,4,4′‐benzophenonetetracarboxylic acid dianhydride/4,4′‐oxydianiline) were investigated for density effects and closed versus open cell effects on the thermal, mechanical, and flammability properties. Thermal conductivity data under the full range of vacuum pressures indicate that these materials are effective insulators under cryogenic conditions. Contributing factors such as cell content, density, and surface area were studied to determine the effects on thermal conductivity. Cone calorimetry data indicated decreased peak heat release rates for the closed cell system, TEEK‐H friable balloons, compared to the TEEK foams with higher open cell content. Mechanical properties including tensile strength and compressive strength indicated that the materials have good structural integrity. Foams with more open cell content resulted in greater tensile and compressive strengths than the closed cell foams. The maximum closed cell content achieved in the “friable balloon” system was 78% at a foam density of 0.048 gm/cm3. Published in 2005 by John Wiley & Sons, Ltd.
Influence of N‐terminal residue stereochemistry on the prolyl amide geometry and the conformation of 5‐tert‐butylproline type VI β‐turn mimics
Authors: Halab Liliane , Lubell* William D. 
Published: January 2005

AbstractThe effects of N‐terminal amino acid stereochemistry on prolyl amide geometry and peptide turn conformation were investigated by coupling both 𝓁‐ and 𝒹‐amino acids to (2S, 5R)‐5‐tert‐butylproline and 𝓁‐proline to generate, respectively, N‐(acetyl)dipeptide N′‐methylamides 1 and 2. Prolyl amide cis‐ and trans‐isomers were, respectively, favored for peptides 1 and 2 as observed by proton NMR spectroscopy in water, DMSO and chloroform. The influence of solvent composition on amide proton chemical shift indicated an intramolecular hydrogen bond between the N′‐methylamide proton and the acetamide carbonyl for the major conformer of dipeptides (S)‐1, that became less favorable in (R)‐1 and 2. The coupling constant (3JNH,α) values for the cis‐isomer of (R)‐1 indicated a ϕ2 dihedral angle value characteristic of a type VIb β‐turn conformation in solution. X‐ray crystallographic analysis of N‐acetyl‐𝒹‐leucyl‐5‐tert‐butylproline N′‐methylamide (R)‐1b showed the prolyl residue in a type VIb β‐turn geometry possessing an amide cis‐isomer and ψ3‐dihedral angle having a value of 157°, which precluded an intramolecular hydrogen bond. Intermolecular hydrogen bonding between the leucyl residues of two turn structures within the unit cell positioned the N‐terminal residue in a geometry where their ϕ2 and ψ2 dihedral angle values were not characteristic of an ideal type VIb turn. The circular dichroism spectra of tert‐butylprolyl peptides (S)‐ and (R)‐1b were found not to be influenced by changes in solvent composition from water to acetonitrile. The type B spectrum exhibited by (S)‐1b has been previously assigned to a type VIa β‐turn conformation [Halab L, Lubell WD. J. Org. Chem. 1999; 64: 3312–3321]. The type C spectrum exhibited by the (R)‐1b has previously been associated with type II′ β‐turn and α‐helical conformations in solution and appears now to be also characteristic for a type VIb geometry. Copyright © 2001 European Peptide Society and John Wiley & Sons, Ltd.
An alternative sampling algorithm for use in liquid chromatography/tandem mass spectrometry experiments
Authors: Kohli Bernhard M. , Eng Jimmy K. , Nitsch Roger M. , Konietzko Uwe 
Published: January 2005

AbstractIn liquid chromatography/tandem mass spectrometry (LC/MS/MS) analyses of complex peptide mixtures, dynamic exclusion functions are used to minimize repeat selections of identical precursors for collision induced dissociation (CID). We describe a new algorithm for the dynamic exclusion of m/z values during LC/MS/MS. Full‐scan based peak exclusion (Fulspec) uses a simplified model of chromatographic peak formation to detect and exclude contaminants present throughout the run or that lead to broad peaks. Therefore, instead of excluding peptides from fragment analysis according to a rigidly predefined time window, the chromatographic properties of the detected analytes are used. The algorithm was tested on two datasets derived from previously published experiments. Fulspec achieves a distribution of CID spectra with minimal tailing on the retention time axis, without resorting to rigid exclusion of m/z values. The procedure further excludes intensities with a bias towards low‐quality CID spectra. This combination frees up valuable analytical capacity. The underlying intensity vs. quality analyses challenge the assumption that abundant precursors automatically give the best identifications. Further validation of the algorithm will require its incorporation by equipment manufacturers into the instrument control programs. Copyright © 2005 John Wiley & Sons, Ltd.
Characterization of microcystins using in‐source collision‐induced dissociation
Authors: Kubwabo Cariton , Vais Natalia , Benoit Frank M. 
Published: January 2005

AbstractThe efficiency of the in‐source collision‐induced dissociation (in‐source CID) technique for the structural characterization of microcystins (MCYSTs) was evaluated. Microcystins that did not contain arginine underwent facile fragmentation to produce characteristic product ions at relatively low cone voltage and could be fully characterized based on their mass spectra. On the other hand, cyclic peptides possessing arginine residues, such as MCYST‐RR, ‐LR, ‐YR and nodularin, were considerably more stable under in‐source CID conditions and required higher cone voltage to induce fragmentation. This behaviour is explained in terms of the mobile proton model for peptide fragmentation that can be used as an indication for the presence of arginine when unknown microcystins are analyzed. In‐source CID was applied to the characterization of microcystins released into water from a Microcystis aeruginosa culture (UTCC299) (UTCC: University of Toronto Culture Collection of Algae and Cyanobacteria). Six microcystins were detected in extracts from UTCC299: I, [D‐Asp3]MCYST‐LR; II, MCYST‐LR; III, isomer of MCYST‐LR; IV, isomer of methyl MCYST‐LR; V, [D‐Asp3, Glu(OCH3)6]MCYST‐LR; and VI, [D‐Glu(OCH3)6]MCYST‐LR. In‐source CID provided mass spectral patterns similar to those obtained by CID in the collision cell of the mass spectrometer but was more sensitive for the analysis of microcystins. Copyright © 2005 John Wiley & Sons, Ltd.