bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mozaik Araştırmalarında Kullanılan Arkeometrik Yöntemler ve Örnekleri
Authors: AYDIN Mahmut 
Published: October 2023

Günümüzde mozaiklerden elde edilecek bilgi sadece motiflerin görsel olarak incelemelerinden ibaret değildir. Tahribatsız ve tahribatlı arkeometrik yöntemler kullanılarak mozaiklerden elde edilecek bilimsel bilgi en üst seviyeye çıkarılabilmektedir. Mozaiklerde kullanılabilecek en yaygın arkeometrik yöntemler tahribatsız olanlardır; mozaiklerde kullanılan renk sayısı ve tonları taşınabilir (Munsell katalog kodunu veren) dijital renk ölçer ile tespit edilebilmektedir. Bunun yanı sıra taşınabilir X Işını Floresans Spektrometresi (P-EDXRF) ile tahribatsız bir şekilde taşları oluşturan elementler tespit edilerek tesseraların türleri belirlenebilmektedir. Cam tesseraların da kimyasal kompozisyonu ve renk vericiler belirlenebilmektedir.
Tahribatlı arkeometrik yöntemlerin kullanılması izinler ve etik açısından her zaman mümkün olmasa da bu yöntemlerden elde edilecek bilimsel bilgiler tahribatsız yöntemlere göre daha fazladır ve güvenilirdir. Mozaiklerde kullanılan harç, taş, cam ve pişmiş toprak tesseraların türlerinin ve içeriklerinin belirlenmesinde yaygın kullanılabilecek arkeometrik yöntemler de şunlardır; petrografik analizler, dalga dağılımlı X Işını Floresans Spektrometresi (WDXRF), Kütle Spektrometresi ve X Ray Detektörlü Taramalı Elektron Mikroskobu (SEM-EDX)’dur. Bu yöntemler kullanılarak cam tesseraların kimyasal kompozisyonu, renk verici kimyasallar, üretim hataları, bozulma nedenleri ve ikincil kullanım ürünü olup olmadığı (geri dönüşüm) gibi bilgiler elde edilebilmektedir. Taş tesseralarda ise tahribatlı arkeometrik yöntemler kullanılarak taş türü ve kökeninin belirlenmesi yapılabilmektedir. Bu çalışmada yazarın mozaikler üzerinde bizzat yürüttüğü arkeometrik yöntemler ve elde ettiği sonuçlar paylaşılacaktır.
INFLUENCE OF EXPERIENTIAL VALUE ON BRAND IMAGE AND CUSTOMER LOYALTY OF VISTA CONCRETE TILES PT. YASKA POST OF THE EARTHQUAKE DISASTER IN THE CITY OF MATARAM
Authors: Husein Saddam , Saufi Akhmad , Handayani Rinuastuti Baiq 
Published: October 2023

This study aims to find out the effect of Experiential Value on Brand image and customer loyalty at PT. Yaska after the earthquake in the city of Mataram using the associative quantitative method with a sample of 40 respondents and using a questionnaire as a tool for collecting data whose results were analyzed using smart PLS through the inner and outer model tests. The results of this study show significant positive results where the Experiential Value on Brand image and customer loyalty where the more positive the Experiential Value received by customers, the better the Brand image of a brand and increase customer loyalty.
Keywords: Experiential Value, Brand Image, Customer Loyalty, Concrete Tiles
Comparison of different definitions of metabolic syndrome and their associations with non-alcoholic fatty liver disease: a retrospective study
Authors: Tse Carmen , Lisanti Nicholas , Grubert Van Iderstine Micah , Uhanova Julia , Minuk Gerald , Faisal Nabiha 
Published: October 2023

Background: Metabolic syndrome (MetS) is considered an important risk factor for non-alcoholic fatty liver disease (NAFLD). The aim of this study was to measure the prevalence of MetS based on six different MetS definitions and compare the performance of various definitions for identifying diabetes, hypertension, and dyslipidemia among NAFLD patients. Methods: The definitions compared were those developed by the World Health Organization (WHO), National Cholesterol Education Program Adult Treatment Panel III (NCEP-ATP III), International Diabetes Federation (IDF), American Association of Clinical Endocrinologists (AACE), American Heart Association/National Heart, Lung and Blood Institute (AHA/NHLBI), and Interim Joint Statement “harmonized” criteria. Receiver operator characteristic (ROC) curves were plotted for the six MetS definitions with NAFLD diagnosis. The diagnosis for NAFLD was established based on liver imaging or biopsy compatible with fatty liver disease. Results: A total of 500 NAFLD patients were analyzed. The mean age was 61.2 (SD 13.2) years, and BMI was 32.7 (SD 8.0) kg/m2. The most prevalent MetS component was dyslipidemia (83%), followed by hypertension (60%), obesity (61%), and diabetes (57%). The prevalence of MetS according to the WHO, NCEP/ATP-III, IDF, AACE, AHA/NHLBI, and harmonized criteria was 69%, 59%, 54%, 64%, 78%, and 79%, respectively. The highest area under the ROC curve for diabetes and hypertension was with the WHO definition (0.7405) and (0.8120), respectively. Conclusions: The prevalence of MetS in NAFLD patients varies according to the definitions of MetS employed. The modified WHO definition appeared to be most useful for the screening of MetS in NAFLD patients.
Doing Ethnography Blind
Authors: Karagoz Orhan 
Published: October 2023

Abstract
Anthropology's ‘mainstream’ research methods mainly rely on the visual sense. In contrast to sighted anthropologists, who mostly rely on their vision to acquire and process data, as a blind anthropologist I have used unconventional methodological sensory research techniques. I mostly rely on my senses of hearing and listening, using auditory means to make sense of people and our environment. Some of these auditory means are eavesdropping, understanding people's emotions through the tone of their voices and understanding the ‘acoustemology’ of spaces. I am highly attuned to the tones of people's voices and to the ambience of the places I am in. During my fieldwork, I was able to capitalise on these senses and abilities as research techniques, but also consider their ethical implications.
The Relationship between Body Mass Index and Left Ventricular Structure and Function in Healthy Adults
Authors: Fawzi Amjad , Aziz Enaas S. 
Published: October 2023

Background: There is considerable evidence which associate cardiovascular morbidity and mortality with obesity, however, a direct effect of uncomplicated obesity on cardiac function is not well established.Objective: To evaluate the relationship between body mass index (BMI) and left ventricular structure and function.Methods: This cross-sectional study was carried out on (146) apparently healthy adults from both sexes (85 male and 61 female) aged 20-59 years(36.49±9.92 ). Subjects were grouped according to BMI into1.normal weight group included 47 subjects (BMI=18.5-24.9Kg/m2);2. Overweight group included 43 subjects (BMI=25-29.5 Kg/m2) and 3. obese group included (56) subjects(BMI≥30). Echocardiographic indices of left ventricular structure and function were obtained. This study was performed between October 2009 till April 2010 at the Echocardiography Unit in Ibn Sina Teaching Hospital in Mosul.Results: There was a significant increase in LVM(left ventricular mass), LVMI(left ventricular mass index), LVIDD(left ventricular internal dimension in diastole) and PWT(posterior wall thickness) among over weight and obese subjects (P< 0.001),however, both contractility indices [LVEF%(left ventricular ejection fraction percent) and LVFS %(left ventricular fractional shortening percent)] seemed unchanged significantly. The left ventricular diastolic function [E/A ratio(ratio of passive to active velocity inflow)] has significantly decreased among the obese group (P< 0.001). This observed decrease in E/A ratio with increasing BMI coincided with a statistically significant increase (P< 0.001) in LAD (left atrial dimensions).Conclusions: Increased body weight is positively correlated with LVM but not with systolic dysfunction. All subjects with isolated obesity have subclinical left ventricular diastolic dysfunction; this correlates with BMI.
Tratamientos aplicados en pacientes por infección de covid-19 con diabetes mellitus tipo 2
Authors: Sánchez Jácome Gissela de los Ángeles , Freire Montesdeoca Jessica Mariana 
Published: October 2023

Introducción. Los coronavirus son virus de ARN que causan diferentes tipos de enfermedades respiratorias. A finales de 2019, se identificó un nuevo coronavirus y el 11 de marzo de 2020 la declaró pandemia. Existe el desarrollo de diabetes en pacientes con SARS-CoV-2, por lo que es posible que pudiera ocasionar alteraciones en el metabolismo de la glucosa que conlleva la aparición de diabetes mellitus. Objetivo. Realizar una revisión bibliográfica sobre los tratamientos aplicados en pacientes infectados con Covid-19 y que tengan como patología de base diabetes mellitus tipo 2. Metodología. Se utilizaron bases de datos como PubMed, Scopus, Springer, Elsevier y se incluyeron artículos en idioma español e inglés publicados dentro del período del año 2019 al año 2023. Resultados. Todos los artículos analizados describen como pilar fundamental del tratamiento el uso de metformina, insulina y corticoides, acompañada de la educación del paciente y la comunicación entre el personal de salud y el paciente. Conclusión. El tratamiento se basa en la medicación habitual del paciente, pero con leves ajustes dependiendo al control de la glucosa, también se han descritos diferentes tratamientos como incretinas, inhibidores ECA, cloroquina e hidroxicloroquina e inhibidores SGLT2 entre otros que han actuado de diferentes formas para el control de dicha patología. Área de estudio general: Medicina. Área de estudio específica: Medicina Interna.
Revisión sistemática de las aplicaciones de vanguardia en el campo de la visión por computadora
Authors: Torres Abril Paulo César , Jara Moya Santiago David , Torres Valverde Leonardo David , Arias Martínez Darwin René 
Published: October 2023

Introducción: La visión artificial combina inteligencia artificial y robótica para analizar imágenes capturadas por cámaras. Se basa en la teoría de la percepción del color RGB y considera factores como la iluminación y el tipo de sensor. Utiliza modelos de color para modificar imágenes con precisión. Se emplean OpenCV y Python en esta investigación sobre técnicas avanzadas en visión artificial, centrándose en la innovación y algoritmos para mejorar la precisión en la clasificación de objetos mediante el aprendizaje automático y redes neuronales. Objetivo: El objetivo principal de este estudio es llevar a cabo un examen exhaustivo de la información disponible acerca de los avances recientes en visión artificial mediante metaanálisis o revisión sistemática, con el fin de abordar de manera más precisa la investigación en este ámbito. Metodología: La investigación se enfoca en la visión artificial, priorizando fuentes científicas recientes en inglés, aunque se incluyen libros y fuentes web confiables en menor medida. Se utiliza un enfoque cualitativo a través de la metodología de Revisión Sistemática de la Literatura (SLR), que abarca la formulación de preguntas, exploración de documentos, selección rigurosa de obras y adquisición de datos relevantes. Resultados: El análisis destaca que la visión por computadora es un campo avanzado con diversas aplicaciones en sistemas de dispositivos inteligentes; también se realizó un análisis de palabras clave para identificar tendencias clave en los artículos seleccionados. Conclusión: La mayoría de los estudios relevantes sobre el tema se hallaron en bases de datos en inglés como IEEE y Springer, con limitadas referencias en Scopus debido a sus costos asociados; el enfoque de este estudio se centra en sistemas inteligentes y su aplicación en la detección de objetos en tiempo real mediante redes neuronales convolucionales. Área de estudio general: Tecnologías de la Información y Comunicación (Tic). Área de estudio específica: Inteligencia artificial.
Inventory of Medicinal Plants The Treatment and Prevention of Malaria in The East Sentani District, Jayapura Regency
Authors: Tukayo Brechkerts Lieske Angruni , Samalo Rahayu 
Published: October 2023

Traditional medicine is still widely used as an alternative medication in society especially in the form of plant material. Malaria is one of a communicable disease with the high number of its incidence in Papua. Traditional plants commonly used by people in Jayapura Regency for malaria treatment are papaya, Carica papaya L. (C. papaya), sambiloto, Andrographis paniculata, (A. paniculata) leaves, milk wood and turmeric. Each was prepared with different processing method including boiled, mashed and grated. However, the literature on the description of malaria treatment using traditional medicine is very limited. This research was carried out with the aim of carrying out an inventory of medicinal plants for the treatment and prevention of malaria in the East Sentani area, Jayapura Regency. This research was a descriptive study performed in 7 villages of East Sentani Timur District, with total sample were 210 respondent data. Respondent was given a questionary to collect data of plants used as prevention and medication for malaria. The results revealed the plants used by the community in East Sentani District in treating and preventing malaria were mostly C. papaya leaves (47.1%), A. paniculata leaves (44.3%) and other plants (under 5%) such as bitter melon (3.3%), and African leaves (1.9%). The plant parts used for the treatment and prevention of malaria were mainly the leaves (98.5%). The method of processing plants was mostly by boiling the plant (88.1%), brewing with hot water (4.8%) and squeezing (4.3%). The way to use of plants for the treatment of malaria was by drinking (97.6%). The dose used by most respondents was mostly by 1 cup (62.9%). The sources of antimalarial medicinal plants from the yard of the house were 108 respondents (51.4%). From this research, plants which widely used in the treatment and prevention of malaria by the people of the East Sentani district were C. papaya and A. paniculata.
The RNA binding proteins ZFP36L1 and ZFP36L2 are dysregulated in airway epithelium in human and a murine model of asthma
Authors: Rynne Jennifer , Ortiz-Zapater Elena , Bagley Dustin C. , Zanin Onofrio , Doherty George , Kanabar Varsha , Ward Jon , Jackson David J. , Parsons Maddy , Rosenblatt Jody , Adcock Ian M. , Martinez-Nunez Rocio T. 
Published: October 2023

Introduction: Asthma is the most common chronic inflammatory disease of the airways. The airway epithelium is a key driver of the disease, and numerous studies have established genome-wide differences in mRNA expression between health and asthma. However, the underlying molecular mechanisms for such differences remain poorly understood. The human TTP family is comprised of ZFP36, ZFP36L1 and ZFP36L2, and has essential roles in immune regulation by determining the stability and translation of myriad mRNAs encoding for inflammatory mediators. We investigated the expression and possible role of the tristetraprolin (TTP) family of RNA binding proteins (RBPs), poorly understood in asthma.Methods: We analysed the levels of ZFP36, ZFP36L1 and ZFP36L2 mRNA in several publicly available asthma datasets, including single cell RNA-sequencing. We also interrogated the expression of known targets of these RBPs in asthma. We assessed the lung mRNA expression and cellular localization of Zfp36l1 and Zfp36l2 in precision cut lung slices in murine asthma models. Finally, we determined the expression in airway epithelium of ZFP36L1 and ZFP36L2 in human bronchial biopsies and performed rescue experiments in primary bronchial epithelium from patients with severe asthma.Results: We found ZFP36L1 and ZFP36L2 mRNA levels significantly downregulated in the airway epithelium of patients with very severe asthma in different cohorts (5 healthy vs. 8 severe asthma; 36 moderate asthma vs. 37 severe asthma on inhaled steroids vs. 26 severe asthma on oral corticoids). Integrating several datasets allowed us to infer that mRNAs potentially targeted by these RBPs are increased in severe asthma. Zfp36l1 was downregulated in the lung of a mouse model of asthma, and immunostaining of ex vivo lung slices with a dual antibody demonstrated that Zfp36l1/l2 nuclear localization was increased in the airway epithelium of an acute asthma mouse model, which was further enhanced in a chronic model. Immunostaining of human bronchial biopsies showed that airway epithelial cell staining of ZFP36L1 was decreased in severe asthma as compared with mild, while ZFP36L2 was upregulated. Restoring the levels of ZFP36L1 and ZFP36L2 in primary bronchial epithelial cells from patients with severe asthma decreased the mRNA expression of IL6, IL8 and CSF2.Discussion: We propose that the dysregulation of ZFP36L1/L2 levels as well as their subcellular mislocalization contributes to changes in mRNA expression and cytoplasmic fate in asthma.
Study of thulium-167 cyclotron production: a potential medically-relevant radionuclide
Authors: Renaldin Edoardo , Dellepiane Gaia , Braccini Saverio , Sommerhalder Alexander , Zhang Hui , van der Meulen Nicholas P. , Eichler Robert , Talip Zeynep 
Published: October 2023

Introduction: Targeted Radionuclide Therapy is used for the treatment of tumors in nuclear medicine, while sparing healthy tissues. Its application to cancer treatment is expanding. In particular, Auger-electron emitters potentially exhibit high efficacy in treating either small metastases or single tumor cells due to their short range in tissue. The aim of this paper is to study the feasibility of a large-scale production of thulium-167, an Auger-electron emitter radionuclide, in view of eventual systematic preclinical studies.Methods: Proton-irradiated enriched erbium-167 and erbium-168 oxides were used to measure the production cross sections of thulium-165, thulium-166, thulium-167, and thulium-168 utilizing an 18-MeV medical cyclotron equipped with a Beam Transport Line (BTL) at the Bern medical cyclotron laboratory. The comparison between the experimental and the TENDL 2021 theoretical cross-section results were in good agreement. Additional experiments were performed to assess the production yields of thulium radioisotopes in the BTL. Thulium-167 production yield was also measured irradiating five different target materials (167Er2O3, 168Er2O3, natTm2O3, natYb2O3, 171Yb2O3) with proton beams up to 63 MeV at the Injector II cyclotron of Paul Scherrer Institute.Results and Discussion: Our experiments showed that an 8-h irradiation of enriched ytterbium-171 oxide produced about 420 MBq of thulium-167 with a radionuclidic purity of 99.95% after 5 days of cooling time with a proton beam of about 53 MeV. Larger activities of thulium-167 can be achieved using enriched erbium-168 oxide with a 23-MeV proton beam, obtaining about 1 GBq after 8-h irradiation with a radionuclidic purity of <99.5% 5 days post end of bombardment.
Combinatorial efficacy of Manuka honey and antibiotics in the in vitro control of staphylococci and their small colony variants
Authors: Liang Jiawei , Adeleye Mowalolaoluwa , Onyango Laura A. 
Published: October 2023

IntroductionStaphylococci are among the list of problematic bacteria contributing to the global antibiotic resistance (ABR) crisis. Their ability to adopt the small colony variant (SCV) phenotype, induced by prolonged antibiotic chemotherapy, complicates staphylococcal infection control options. Novel and alternative approaches are needed to tackle staphylococcal infections and curb ABR. Manuka honey (MH), a non-antibiotic alternative is recognized for its unique antibacterial activity based on its methylglyoxal (MGO) component.MethodsIn this study, MH (MGO 830+) was tested in combination with gentamicin (GEN), rifampicin (RIF), or vancomycin (VA) against staphylococcal wildtype (WT) and SCVs. To our knowledge, there are no current studies in the literature documenting the effects of MH on staphylococcal SCVs. While Staphylococcus aureus is well-studied for its international ABR burden, limited data exists demonstrating the effects of MH on S. epidermidis and S. lugdunensis whose pathogenic relevance and contribution to ABR is also rising.Results &amp; discussionThe three staphylococci were most susceptible to RIF (0.06-0.24 μg/ml), then GEN (0.12-0.49 μg/ml), and lastly VA (0.49-0.96 μg/ml). The MICs of MH were 7%, 7-8%, and 6-7% (w/v), respectively. Fractional inhibitory concentration (FIC) evaluations showed that the combined MH + antibiotic effect was either additive (FICI 1-2), or partially synergistic (FICI &gt;0.5-1). While all three antibiotics induced SCVs in vitro, stable SCVs were observed in GEN treatments only. The addition of MH to these GEN-SCV-induction analyses resulted in complete suppression of SCVs (p&lt;0.001) in all three staphylococci, suggesting that MH’s antibacterial properties interfered with GEN’s SCV induction mechanisms. Moreover, the addition of MH to growth cultures of recovered stable SCVs resulted in the inhibition of SCV growth by at least 99%, indicating MH’s ability to prevent subsequent SCV growth. These in vitro analyses demonstrated MH’s broad-spectrum capabilities not only in improving WT staphylococci susceptibility to the three antibiotics, but also mitigated the development and subsequent growth of their SCV phenotypes. MH in combination with antibiotics has the potential to not only resensitize staphylococci to antibiotics and consequently require less antibiotic usage, but in instances where prolonged chemotherapy is employed, the development and growth of SCVs would be hampered, providing a better clinical outcome, all of which mitigate ABR.
Gauging trauma-informed pedagogy in higher education: a UK case study
Authors: Bitanihirwe Byron , Imad Mays 
Published: October 2023

IntroductionA substantial amount of evidence suggests a negative association between traumatic experiences and mental health among primary and secondary school students. These vulnerable students are at an increased risk of academic, social, and emotional problems. However, there is limited evidence on the connection between traumatic experiences and student mental health in higher education, especially regarding trauma-related content in classrooms. This study aims to explore students’ experiences with traumatic material in a UK university setting and to understand educators’ perceptions of trauma-informed pedagogy.MethodsEight students from the University of Manchester and seven educators (from the humanities and social sciences departments) participated in one-on-one semi-structured interviews. The analysis adopted an inductive thematic approach.ResultsFour major themes emerged from the interview data: Inclusion and delivery of trauma-related content in higher education; Effects of trauma-related content on class attendance; Availability of support systems for handling trauma-related content; Perceptions on trauma-informed education.DiscussionThe implications of this study for future research and current teaching practices are discussed. Recommendations are provided for teaching sensitive material. Limitations of this study, such as sample size and demographics, are acknowledged. Additionally, a conceptual framework for trauma-informed pedagogy is introduced, laying the groundwork for an upcoming concept paper.