bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined Ravitch and Nuss procedure for patients with severe pectus excavatum: technique and initial results
Authors: Masai Kyohei , Okubo Yu , Kaseda Kaoru , Hishida Tomoyuki , Asakura Keisuke 
Published: November 2023

Abstract
The Nuss procedure for pectus excavatum (PE) is both less invasive and very simple compared to the Ravitch procedure. However, it may be difficult to perform the Nuss procedure in cases of severe PE. Therefore, we developed a Combined Ravitch and Nuss (CRN) procedure and examined its effectiveness in patients with severe PE. Nine patients with severe PE underwent the CRN procedure. Data on patient characteristics and perioperative results were collected retrospectively. The median Haller index (HI) was 15.4 (range, 6.3–29.3). No significant intraoperative adverse events were noted. Postoperatively, marked improvements in HI were seen in all cases (3.29, range, 2.72–4.96). Two surgical site infections on the shallow layer and one wound seroma occurred. No recurrences were observed during the observation period. Our novel CRN procedure is useful for achieving adequate and sustainable sternal elevation with less invasiveness for patients with severe PE.
Fluorescence guidance during robotic resection of bladder wall endometriosis: case report and technique
Authors: Bruneel Yasnaia , Ghysel Christophe , Van Holsbeke Caroline , Van Trappen Philippe 
Published: November 2023

Abstract
The application of indocyanine green (ICG) has recently been reported to aid in the resection of endometriosis in the bladder wall and/or involving the ureters. A symptomatic 41-year-old patient with dysmenorrhea and pollakisuria was referred to our tertiary center. Imaging revealed a 1.5–2 cm intramural endometriotic nodule in the posterior bladder wall. She was planned for robotic resection of the endometriotic nodule, under ICG guidance, together with a hysterectomy. After placement of double-J ureteral stents and clamping the bladder, perforation of the bladder mucosa could be avoided whilst performing a circumferential resection of the nodule. By clamping the bladder catheter after instillation of ICG, both the bladder wall thickness and ureters could be visualized with near-infrared imaging during robotic resection of the endometriotic nodule and hysterectomy. With the surgical approach described here, endometriotic nodules/tissue can be removed precisely with enlarged vision at the robot console, safely, and completely without damaging adjacent tissues.
Repair of penile prosthesis–induced impending erosion using xenograft during simultaneous inflatable penile prosthesis replacement
Authors: Jue Joshua S , Eid Jean-Francois 
Published: November 2023

Abstract

Background
Penile prosthesis (PP)–induced impending erosion is a rare complication that has not been well characterized.

Aim
This study evaluates the role of prosthesis sizing and of the safety of xenograft windsock repair (AlloDerm, Tutoplast, ArthroFLEX) of impending erosion.

Methods
This was a retrospective review of xenograft use during inflatable penile prosthesis (IPP) replacement. Patient demographics, prior PP characteristics, and xenograft-augmented IPP characteristics were obtained. Paired-samples t tests were used to compare the PP cylinder size, rear tip extender size, and calculated PP length between the most recent prior PP and the xenograft-augmented IPP. Complications and follow-up data were obtained.

Outcomes
The primary outcome was comparing the corporal body and device measurements between the PP presenting with impending erosion and the implanted xenograft-augmented IPP. The secondary outcome was evaluating the incidence of subsequent explantation.

Results
A total of 24 patients underwent xenograft repair with simultaneous IPP replacement from 2012 to 2022. The median number of prior PP was 1 (interquartile range, 1-2.75). The median time between the most recent prior PP and xenograft-augmented IPP placement was 21 (interquartile range, 14-79) months. The prior PP was significantly longer at the time of explantation compared with the measured corporal body length in both the left (21.4 cm vs 20.1 cm; P &lt; .01) and right (21.4 cm vs 20.1 cm; P &lt; .01) sides. However, there was no significant difference in length between the xenograft-augmented IPP length at the time of implantation and measured corporal body length in both the left (20.1 cm vs 20.0 cm; P = .67) and right (20.2 cm vs 20.1 cm; P = .56) sides. A total of 16 (66.7%) cases required bilateral xenograft corporal body use. Only 1 (4.2%) patient had an IPP infection requiring explantation within 90 days of xenograft-augmented IPP placement. A total of 2 (8.3%) patients had device malfunction and 1 (4.2%) patient had impending erosion recurrence requiring removal/replacement of their initial xenograft-augmented IPP in a median time of 56 months from placement.

Clinical Implications
PP oversizing may increase risk of PP-induced impending erosion, which is a delayed process.

Strengths and Limitations
This is the largest retrospective study of xenograft use during IPP replacement for impending erosion but does not have a control cohort. This study is limited by its retrospective nature, limited follow-up, and absence of a treatment comparison.

Conclusion
PP-induced impending erosion may be due to PP oversizing but can be successfully repaired with xenograft windsock during simultaneous IPP replacement.
Urinary symptoms and female sexual dysfunction in women with type 1 diabetes: the role of depression
Authors: Fernandez Moncaleano Golena , Gibbons Cody M , Holt Sarah , Braffett Barbara , Pop-Busui Rodica , Jacobson Alan , Wessells Hunter , Sarma Aruna 
Published: November 2023

Abstract

Background
Some reports suggest that women with type 1 diabetes (T1D) have a greater burden of female sexual dysfunction (FSD) than women without T1D, but the etiology of this elevated risk is poorly understood.

Aim
To examine the associations between FSD and urinary incontinence/lower urinary tract symptoms (UI/LUTS) in women with T1D and to evaluate how depression may mediate these relationships.

Methods
LUTS and UI symptoms were assessed in women with T1D who participated in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study. Multivariable logistic regression models estimated associations between FSD and UI/LUTS (overall and specific domains) and the impact of depression on these associations.

Outcomes
FSD was measured with the Female Sexual Function Index–Reduced.

Results
In total, 499 self-reported sexually active women completed validated assessments of sexual and urinary function (mean ± SD age, 47.7 ± 7.6 years; T1D duration, 23.4 ± 5.15 years). FSD was reported in 232 (46%) responders. The frequency of UI and LUTS was 125 (25.1%) and 96 (19.2%), respectively. Neither UI nor its subcategories (urge, stress) were associated with FSD. Although LUTS (odds ratio [OR], 1.75; 95% CI, 1.09-2.77) and its symptoms of urgency (OR, 1.99; 95% CI, 1.09-3.61) and incomplete emptying (OR, 2.44; 95% CI, 1.23-4.85) were associated with FSD, these associations were attenuated following adjustment for depression and antidepressant medication use. Depression indicators were independently associated with FSD overall and across domains.

Clinical Implications
The complex interplay of voiding dysfunction, mental health, and sexual function warrants further investigation to understand the potential implications for patient assessment, goal setting, treatment, and care planning.

Strengths and Limitations
Data are from a prospective study of individuals with T1D. These results are unable to explore cause-and-effect relationships among LUTS, UI, depression, and FSD. The sample may not be representative of the general population of women with T1D. Because participants in the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study are mostly White, generalizing the findings to other races and to type 2 diabetes may not be appropriate. While exclusion of sexually inactive women likely biases our findings toward the null, this design element permitted study of LUTS and UI in relation to aspects of FSD, the primary objective of this study.

Conclusions
The significant associations between LUTS/UI and FSD among middle-aged women with T1D were greatly attenuated when depression was considered a mediating factor.
Interventions to increase vaccination against COVID-19, influenza and pertussis during pregnancy: a systematic review and meta-analysis
Authors: Razai Mohammad S , Mansour Rania , Goldsmith Lucy , Freeman Samuel , Mason-Apps Charlotte , Ravindran Pahalavi , Kooner Pavan , Berendes Sima , Morris Joan , Majeed Azeem , Ussher Michael , Hargreaves Sally , Oakeshott Pippa 
Published: November 2023

Abstract

Background
Pregnant women and their babies face significant risks from three vaccine-preventable diseases: COVID-19, influenza and pertussis. However, despite these vaccines’ proven safety and effectiveness, uptake during pregnancy remains low.

Methods
We conducted a systematic review (PROSPERO CRD42023399488; January 2012–December 2022 following PRISMA guidelines) of interventions to increase COVID-19/influenza/pertussis vaccination in pregnancy. We searched nine databases, including grey literature. Two independent investigators extracted data; discrepancies were resolved by consensus. Meta-analyses were conducted using random-effects models to estimate pooled effect sizes. Heterogeneity was assessed using the I2 statistics.

Results
From 2681 articles, we identified 39 relevant studies (n = 168 262 participants) across nine countries. Fifteen studies (39%) were randomized controlled trials (RCTs); the remainder were observational cohort, quality-improvement or cross-sectional studies. The quality of 18% (7/39) was strong. Pooled results of interventions to increase influenza vaccine uptake (18 effect estimates from 12 RCTs) showed the interventions were effective but had a small effect (risk ratio = 1.07, 95% CI 1.03, 1.13). However, pooled results of interventions to increase pertussis vaccine uptake (10 effect estimates from six RCTs) showed no clear benefit (risk ratio = 0.98, 95% CI 0.94, 1.03). There were no relevant RCTs for COVID-19. Interventions addressed the ‘three Ps’: patient-, provider- and policy-level strategies. At the patient level, clear recommendations from healthcare professionals backed by text reminders/written information were strongly associated with increased vaccine uptake, especially tailored face-to-face interventions, which addressed women’s concerns, dispelled myths and highlighted benefits. Provider-level interventions included educating healthcare professionals about vaccines’ safety and effectiveness and reminders to offer vaccinations routinely. Policy-level interventions included financial incentives, mandatory vaccination data fields in electronic health records and ensuring easy availability of vaccinations.

Conclusions
Interventions had a small effect on increasing influenza vaccination. Training healthcare providers to promote vaccinations during pregnancy is crucial and could be enhanced by utilizing mobile health technologies.
Evolution of Humoral and Cellular Immunity Post–Breakthrough Coronavirus Disease 2019 in Vaccinated Patients With Hematologic Malignancy Receiving Tixagevimab-Cilgavimab
Authors: Hall Victoria G , Nguyen Thi H O , Allen Lilith F , Rowntree Louise C , Kedzierski Lukasz , Chua Brendon Y , Lim Chhay , Saunders Natalie R , Klimevski Emily , Tennakoon Gayani S , Seymour John F , Wadhwa Vikas , Cain Natalie , Vo Kim L , Nicholson Suellen , Karapanagiotidis Theo , Williamson Deborah A , Thursky Karin A , Spelman Timothy , Yong Michelle K , Slavin Monica A , Kedzierska Katherine , Teh Benjamin W 
Published: November 2023

Abstract

Background
In-depth immunogenicity studies of tixagevimab-cilgavimab (T-C) are lacking, including following breakthrough coronavirus disease 2019 (COVID-19) in vaccinated patients with hematologic malignancy (HM) receiving T-C as pre-exposure prophylaxis.

Methods
We performed a prospective, observational cohort study and detailed immunological analyses of 93 patients with HM who received T-C from May 2022, with and without breakthrough infection, during a follow-up period of 6 months and dominant Omicron BA.5 variant.

Results
In 93 patients who received T-C, there was an increase in Omicron BA.4/5 receptor-binding domain (RBD) immunoglobulin G (IgG) antibody titers that persisted for 6 months and was equivalent to 3-dose-vaccinated uninfected healthy controls at 1 month postinjection. Omicron BA.4/5 neutralizing antibody was lower in patients receiving B-cell–depleting therapy within 12 months despite receipt of T-C. COVID-19 vaccination during T-C treatment did not incrementally improve RBD or neutralizing antibody levels. In 16 patients with predominantly mild breakthrough infection, no change in serum neutralization of Omicron BA.4/5 postinfection was detected. Activation-induced marker assay revealed an increase in CD4+ (but not CD8+) T cells post infection, comparable to previously infected healthy controls.

Conclusions
Our study provides proof-of-principle for a pre-exposure prophylaxis strategy and highlights the importance of humoral and cellular immunity post–breakthrough COVID-19 in vaccinated patients with HM.
Population viability analysis informs Western Grasswren translocation: Multi-population sourcing of 112 founder individuals needed to meet success criteria
Authors: Gibson Vega Aline , Ridley Amanda R , Burbidge Allan H , Hall Michelle L , Cowen Saul J 
Published: November 2023

AbstractConservation translocations have become an increasingly popular method to restore or secure vulnerable populations. However, translocations greatly vary in success. The use of population viability analysis (PVA) may increase the likelihood of meeting translocation goals. However, the quality of PVAs to inform translocations is dependent on the availability of ecological data and clear translocation objectives to guide them. Here, we used PVAs to inform the planned conservation translocation of the Western Grasswren (Amytornis textilis textilis) from mainland Shark Bay onto Dirk Hartog Island, Western Australia. A range of translocation scenarios were modelled and scored against success criteria as determined by translocation objectives. Simulations of 20-yr outcomes found that a minimum founder population of 112 individuals meet all success criteria. PVA supported sourcing individuals from 2 subpopulations to maximize genetic diversity. No impact to source populations was detected for the proposed harvest quantities despite conservative estimates of initial source population sizes. Here we demonstrate that creating clear, measurable objectives alongside a PVA lessens ambiguity about which translocation scenarios could be viable. In doing so, we have identified the minimum translocation sizes needed to maintain genetic diversity and population growth, thus increasing the likelihood of translocation success without impacting the source population.
The Establishment of the Pantheon Opera
Authors: Milhous Judith , Dideriksen Gabridla , Hume Robert D 
Published: November 2023

Abstract
The Pantheon Opera came into existence because the Italian opera company at the King’s Theatre, Haymarket, had fallen into a state of debt and disarray. The fire of June 1789 that destroyed the old King’s Theatre was merely a convenient excuse for instituting a change: Lord Chamberlain Salisbury had been looking for a suitable occasion at least since the summer of 1785. As has been explained in Volume I, the old opera-house accumulated so ruinous a set of debts between 1778 and 1783 that it was never again really a stable enterprise. Only a new venue and new ownership could have allowed Italian opera to escape from the debts that had been run up so irresponsibly.
The Pantheon Experiment, I790-9I
Authors: Milhous Judith , Dideriksen Gabridla , Hume Robert D 
Published: November 2023

Abstract
Advance publicity notwithstanding, the Pantheon was rather slow to open. Reporting the state of affairs at the rival opera-houses on 5 January 1791, The Times told its readers, ‘The Pantheon is nearly ready for opening, the machinery was compleated yesterday evening, the dresses are made, the roof of the new stage covered in, and the boxes almost finished. What remains principally to be done is in the stage.’ Fruitless merger negotiations dragged on for the next three weeks, but even then the theatre was apparently in no condition to exhibit public performances.
The Return to the King’s Theatre, Haymarket, I792-I795
Authors: Milhous Judith , Dideriksen Gabridla , Hume Robert D 
Published: November 2023

Abstract
In the summer of 1792 the future of opera in London was seeded in a complicated secret treaty known to its signatories as The General Opera Trust Deed’. Or perhaps ‘supposed to be settled’ would be a more accurate phrasing, for like many peace treaties it failed to achieve its objects. In one sense, the story of the Pantheon was now over: the great experiment had proved a disaster in its one real season, and lacking any other suitable venue, Italian opera had to return to the rebuilt King’s Theatre, Haymarket. But though the Pantheon itself had been an expensive disaster for its secret backers, they had by no means abandoned their hope of establishing a kind of court opera or resigned themselves to a company directed by the egregious William Taylor.
Introduction to Part II
Authors: Milhous Judith , Dideriksen Gabridla , Hume Robert D 
Published: November 2023

Abstract
Part I of this book tells the story of the Pantheon Opera, carried through to the decisive failure to impose the vision of its backers and displace William Taylor as owner and manager of the successor venture at the King’s Theatre, Haymarket. In Part II we turn to analysis of management, production circumstances, repertoire, and the finances that spelt death to the company.
The Opera
Authors: Milhous Judith , Dideriksen Gabridla , Hume Robert D 
Published: November 2023

Abstract
The Pantheon was established by its aristocratic backers with a distinct artistic plan for the opera company: opera seria rather than the increasingly more popular opera buffa was to form the core of the repertoire. The company’s financial problems, the failure to engage a house composer capable of creating major new works, as well as illness amongst the opera seria singers soon enforced a much greater reliance on opera buffa, with almost three quarters of all performances during the 1790-91 season given over to that genre. Moreover, only one opera was specifically created for the Pantheon. Had O’Reilly succeeded in bringing Mozart or Paisiello to London, the repertoire might well have taken on a completely different shape.
Hungary
Authors: Aczel Richard 
Published: November 2023

Abstract
Thus Péter Esterházy (b. 1950), one of Hungary’s most interesting and talented contemporary novelists, writing at the end of 1989, the year that saw the collapse of Communism and the beginnings of the transition to parliamentary democracy throughout East Central Europe. Esterházy’s caution is significant. As a writer who has proved consistently critical of his nation’s political and historical preconceptions, he is quick to insist on continuities easily overlooked in the euphoria of political transformation. He belongs to a generation of writers profoundly distrustful of the rhetoric of political commitment and social progress that not only permeated official Hungarian culture in the period of state socialism, but which also has much deeper roots in the national literary tradition.
Ireland
Authors: Craig Patricia 
Published: November 2023

Abstract
In an essay of 1983, entitled ‘Ireland at Swim’, Denis Donoghue quoted a passage from Yeats’s Memoirs: ‘Practical movements are created out of emotions expressed long enough ago to have become general, but literature discovers; it can never repeat. It is the attempt to repeat an emotion because it has been found effective which has made all politically provincial literature ... so superficial.’ Donoghue extends the insight to present-day Ireland, and to Northern Ireland in particular, about which, he says, ‘discussion ... is interminable and frustrating. No one is thinking. Everyone is merely repeating an emotion he has found effective: effective in the sense of making him and his position familiar.’
Italy
Authors: Hainsworth Peter 
Published: November 2023

Abstract
Between the late 1950s and the mid-1970s, Italy became a modem European country. The abruptness of the transition made itself felt particularly in the early 1960s, startling, perhaps traumatizing, most of the country’s inhabitants, writers included. Most of those who were to be the significant names of the period were already well into their careers when the ‘boom’ or ‘economic miracle’ burst upon them. Some were already well known before the war. They now found themselves living through radical changes: the loss of the old peasant cultures, with their dialects and traditions, unconstrained urban expansion (especially in the north), rapid industrialization, the growth of consumerism and modem media. In short, the country went through a now familiar process of assimilation to modem economic and social patterns and structures.
Capital Regulation and Shadow Finance: A Quantitative Analysis
Authors: Lee Hyunju , Lee Sunyoung , Paluszynski Radoslaw 
Published: November 2023

Abstract
This article studies the effects of higher bank capital requirements. Using new firm-lender matched credit data from South Korea, we document that Basel III coincided with a 25% decline in credit from regulated banks, and an increase of similar magnitude from non-bank (shadow) lenders. We use our data to estimate the effect of capital requirements on bank credit, and the spillover effect of the reform on non-bank lending. We then build a general equilibrium model with heterogeneous banks and firms that replicates these micro estimates. We find that Basel III can account for most of the observed decrease in regulated bank lending and about three quarters of the increase in shadow lending. The latter is driven exclusively by general equilibrium effects of the reform.
Bargaining as a Struggle Between Competing Attempts at Commitment
Authors: Dutta Rohan 
Published: November 2023

Abstract
The strategic importance of commitment in bargaining is widely acknowledged. Yet disentangling its role from key features of canonical models, such as proposal power and reputational concerns, is difficult. This paper introduces a model of bargaining with strategic commitment at its core. Following Schelling (1956, The American Economic Review, vol. 46, 281–306), commitment ability stems from the costly nature of concession and is endogenously determined by players’ demands. Agreement is immediate for familiar bargainers, modelled via renegotiation-proofness. The unique prediction at the high concession cost limit provides a strategic foundation for the Kalai bargaining solution. Equilibria with delay feature a form of gradualism in demands.
From routine sample measurements in CEA to the Oklo phenomenon
Authors: Dozol Jean-François 
Published: November 2023

Abstract
In 1972, before shipping natural uranium to the USSR for enrichment operations in 235 U, the analysts at Pierrelatte plant noted a slight deficit in 235U: 0.7171 instead of 0.7202. The Direction des Productions of the CEA launched a vast campaign of analyses for the different mines exploited, at all stages of the elaboration of uranium; for this analysis campaign, the Direction des Productions relied on the analytical laboratory of the Pierrelatte plant and on the Central Analytical Laboratory of the CEA where I was in charge of analyses by mass spectrometry.