bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting neutralization susceptibility to combination HIV-1 monoclonal broadly neutralizing antibody regimens
Authors: Williamson Brian D. , Wu Liana , Huang Yunda , Hudson Aaron , Gilbert Peter B. 
Published: December 2023

AbstractCombination monoclonal broadly neutralizing antibodies (bnAbs) are currently being developed for preventing HIV-1 infection. Recent work has focused on predicting in vitro neutralization potency of both individual bnAbs and combination regimens against HIV-1 pseudoviruses using Env sequence features. To predict in vitro combination regimen neutralization potency against a given HIV-1 pseudovirus, previous approaches have applied mathematical models to combine individual-bnAb neutralization and have predicted this combined neutralization value; we call this the combine-then-predict (CP) approach. However, prediction performance for some individual bnAbs has exceeded that for the combination, leading to another possibility: combining the individual-bnAb predicted values and using these to predict combination regimen neutralization; we call this the predict-then-combine (PC) approach. We explore both approaches in both simulated data and data from the Los Alamos National Laboratory’s Compile, Neutralize, and Tally NAb Panels repository. The CP approach is superior to the PC approach when the neutralization outcome of interest is binary (e.g., neutralization susceptibility, defined as inhibitory concentration<1 µg/mL. For continuous outcomes, the CP approach performs at least as well as the PC approach, and is superior to the PC approach when the individual-bnAb prediction algorithms have poor performance. This knowledge may be used when building prediction models for novel antibody combinations in the absence of in vitro neutralization data for the antibody combination; this, in turn, will aid in the evaluation and down-selection of these antibody combinations into prevention efficacy trials.
Ultrasound-Assisted Hydrolysis of Food Waste using Glucoamylase: Statistical Optimization and Mechanistic Analysis with Molecular Simulations
Authors: Anand Avinash , Kumar Karan , Khaire Kaustubh Chandrakant , Roy Kuldeep , Moholkar Vijayanand Suryakant 
Published: December 2023

AbstractFood waste represents a promising and cost-effective resource for synthesizing value-added products through a fermentative pathway. Preceding fermentation, the hydrolysis of food waste into monomeric sugars is a crucial step. This study presents a comprehensive investigation of food waste hydrolysis, encompassing experimental and computational approaches, using glucoamylase (GLCM) enzyme. Initial optimization of hydrolysis parameters was conducted through the Box–Behnken design of experiments, resulting in a total reducing sugar yield (TRS) of 263.4 mg/g biomass under optimized conditions within 42 hours. Sonication of hydrolysis mixture at 35 kHz at 20% duty cycle, yielded a 4× reduction in hydrolysis time with 22% enhancement in TRS yield (320 mg/g biomass). Analysis of GLCM’s secondary structure revealed sonication-induced changes through FTIR spectra deconvolution in both control and test experiments. Sonication led to a reduction in α-helix content and an increase in random coil content. Molecular dynamics simulations, including molecular docking, unveiled the majority of amino acid residues associated with the GLCM binding pocket in the α-helix and random coil regions. Consequently, sonication widened the binding pockets, facilitating easier transport of substrate and product. This effect translated into improved reaction kinetics in food waste hydrolysis.Research HighlightsStatistical optimization of food waste hydrolysis: TRS yield = 263.4 mg/g in 42 h4x reduction of hydrolysis time, 22% rise in TRS yield with 35 kHz sonicationSonication reduced α-helix content & increased random coil content of glucoamylaseMolecular docking simulation to deduce mechanism of ultrasound-assisted hydrolysisMD simulations reveal widening of binding pockets and enhancing catalytic efficiency
LMX and a perceived supportive environment for corporate entrepreneurship: the mediating role of psychological empowerment
Authors: Yasmin Mariam , Zeytonli Asiye , Houghton Jeffery D. , Hardway Lewis 
Published: December 2023

Purpose
This paper aims to explore the potential explanatory mechanisms linking leader–member exchange (LMX) and a perceived supportive environment for corporate entrepreneurship. Specifically, this paper develops and tests a hypothesized moderated mediation model of the relationship between LMX and a perceived supportive environment for corporate entrepreneurship through psychological empowerment as conditional upon the level of control orientation.

Design/methodology/approach
Data were collected from a sample of 682 full-time working adults in the USA and were examined in a moderated mediation model in PROCESS.

Findings
The findings suggest that higher LMX augments perceptions of a supportive environment for corporate entrepreneurship with a mediating role for psychological empowerment and a moderating role for control orientation on that conditional relationship.

Research limitations/implications
This research suggests that high quality LMX relationships may enrich the human capital of firms, helping them to innovate and outperform competitors in the context of modern competitive dynamics. The study findings are limited by several factors including a cross-sectional design and a student-recruited sampling approach.

Originality/value
The study offers unique contributions to the leadership and entrepreneurship literature by being among the first to empirically investigate the relationship between LMX and a perceived supportive environment for corporate entrepreneurship as mediated by psychological empowerment and moderated by control orientation, yielding important insights regarding effective leadership practices for facilitating innovative behaviors and corporate entrepreneurship.
Linking interacting/engaging environmental CSR communication strategy and employees' pro-environmental behaviors (PEBs): mediating roles of communal relationship and employee empowerment
Authors: Dong Enzhu , Sun Ruoyu , Lee Yeunjae 
Published: December 2023

PurposeWith the growing concern for environmental and sustainability issues, especially in the aftermath of the coronavirus disease 2019 (COVID-19) pandemic, organizations feel compelled to pursue green sustainability in their operations. In this regard, the active involvement of employees in pro-environmental behaviors (PEBs) is crucial for achieving organizational environmental sustainability goals (Saeed et al., 2019). To shed light on this important issue, this study aims to investigate the impact of interacting/engaging environmental corporate social responsibility (CSR) communication strategy on employees' PEBs through the mediating effects of communal relationship and employee empowerment.Design/methodology/approachA total of 443 full-time USA employees working across various industries participated in an online survey.FindingsThe interacting/engaging environmental CSR communication strategy fosters employees' perceived communal relationship with their organizations and empowers them to support their organization's environmental initiatives, which, in turn, positively influences employees' PEBs at work.Originality/valueThis study advances CSR and internal communication literature through the lens of relationship management and self-determination theories. The findings theoretically suggest the effectiveness of the interacting/engaging environmental CSR communication strategy in nurturing favorable employee–organization relationships (EORs), employee empowerment and PEBs at work. The practical implications of CSR communication are also elaborated.
“We don’t even know where it’s kept”: exploring perspectives on naloxone administration by provincial correctional workers in Manitoba, Canada
Authors: Ricciardelli Rose Rosemary , Johnston Matthew S. , Maier Katharina 
Published: December 2023

Purpose
Prisonersare at disproportionate risk of suffering substance-related harms. The administration of naloxone is essential to reversing opioid overdose and minimizing substance-related harms in prison and the community. The purpose of this study is to examine how naloxone administration is practiced and perceived in prison settings.

Design/methodology/approach
The authors conducted surveys with correctional workers in Manitoba, Canada (n = 257) to examine how they understand and feel about the need for and practice of administering naloxone in their everyday work with criminalized populations.

Findings
Respondents reported feeling a great need to administer naloxone, but most did not feel adequately trained to administer naloxone, creating the perception that criminalized populations remain at enhanced risk.

Originality/value
Findings provide emerging evidence of the need for training and accompanying policies and procedures for correctional workers on how to access and administer naloxone.
Income diversification and bank performance: an evidence from emerging economy of Pakistan
Authors: Ashraf Yasir , Nazir Mian Sajid 
Published: December 2023

Purpose The income structure of banks has undergone a notable change in recent decades; therefore, non-interest-based activities have gained much attention. This paper aims to examine the impact of income diversification on bank performance in Pakistan.Design/methodology/approach A balanced panel data set of 20 Pakistani commercial banks is used from 2007 to 2020. The random effect model is employed to test the relationship between income diversification and financial performance.Findings The empirical results indicate a significant positive impact of income diversification of banks on risk-adjusted returns on assets and equity. Moreover, while banks' risk-adjusted profit performance improves with the increase in bank size, equity ratio and loan ratio, it deteriorates with high credit risk and technology. However, geographical diversification does not explain financial performance in all the risk-adjusted return on equity models. Among the macroeconomic factors, the interest rate influences bank risk-adjusted returns positively, whereas gross domestic product and inflation rate have a negative effect on banks' financial performance.Originality/value To the best of the author's knowledge, this study is the first to empirically investigate the relationships between income diversification and the risk-adjusted profits of Pakistani-listed commercial banks. This study has implications for regulators and policymakers of commercial banks.
Remittances and economic growth: a blessing for middle-income countries, ineffective for low-income countries
Authors: Azizi SeyedSoroosh , Aftabi Abed , Azizkhani Mohsen , Yektansani Kiana 
Published: December 2023

PurposeThis study investigates the impact of international remittances on the economic growth of remittance-receiving countries, using data from 113 developing countries between 1990 and 2015.Design/methodology/approachThe authors used a novel approach to address the potential endogeneity of remittances. The authors estimated bilateral remittances and use them to create weighted indicators of remittance-sending countries, which the authors then use as instruments for remittance inflows to remittance-receiving countries.FindingsThe results indicate that while remittances have a positive impact on economic growth in developing countries with high human capital, they do not contribute to growth in developing countries with low human capital. The authors also examined the channels through which remittances affect growth. The findings suggested that remittances do not impact labor supply in developing countries with high human capital, but they reduce labor supply in countries with low human capital. Additionally, remittances increase investment in physical capital in developing countries with high human capital, but they do not have an effect on investment in developing countries with low human capital.Originality/valueThe authors investigated the impact of remittances on economic growth using a novel approach to address the endogeneity of remittances. Additionally, the authors examined the different indirect channels through which remittances can impact economic growth, such as their effect on labor supply and investment.
SDG commentary: collaboration services for sustainable development goal (SDG) partnerships
Authors: Fisk Raymond P. , Kabadayi Sertan , Sidaoui Karim , Tsiotsou Rodoula H. 
Published: December 2023

Purpose
The purpose of this commentary is to complete the synthesis of the United Nations 17 Sustainable Development Goals (SDGs) into Seven Commentaries on Service Research Themes developed by ServCollab and the Journal of Services Marketing. As an approach to achieving SDG #17, ServCollab’s collaborative logic and design perspective for collaboration services for sustainable development partnerships are presented.

Design/methodology/approach
Collaboration is ServCollab’s Service Research Theme #7, which reframes the UN SDG meta goal #17 of Partnerships. In prior ServCollab research, four possible human interactions were identified: conflict, competition, cooperation and collaboration. Only the shared purpose of collaboration enables elevating the human experience.

Findings
The authors found no published service research that studied SDG #17, which means there are huge opportunities for service research on the role of collaboration in service systems. The alignment between the UN SDGs and ServCollab’s goals is explored. A research agenda for service research and SDG goals was proposed for collaborative communications, collaborative technologies and collaborative projects.

Practical implications
Practical ideas are offered for serving humanity through collaboration. Collaborations are the only practical solutions to humanity’s myriad sustainable development problems.

Social implications
When the United Nations developed its first 16 SDGs, they knew that accomplishing these goals required complex collaborations. That is why SDG #17 is Partnerships. ServCollab’s serving humanity logic applies collaboration to all social settings (large or small) where working together can sustain and regenerate the service ecosystem of Planet Earth.

Originality/value
This commentary describes a unique approach to building collaborative capacity for conducting service research projects for sustaining and regenerating the service ecosystem of Planet Earth.
The role of environmental work in supporting child desistance
Authors: Oswald Rebecca 
Published: December 2023

Purpose
This paper aims to explore how environmental employment can promote desistance among criminalised children. Research demonstrates that being immersed in and interacting with the natural environment has a positive impact upon well-being and behaviour, including reduced aggressive and violent behaviours. However, how exposure to the natural environment might promote desistance amongst children with persistent criminal involvement is unclear.

Design/methodology/approach
This paper examines, through semi-structured interviews and participant observations, the experiences of n = 23 criminalised children aged 16–18 employed in outdoor work at a UK social enterprise.

Findings
The findings demonstrate how working in the natural environment can provide a safe space for children, where they can build positive relationships, learn valuable skills and reconnect with the world outside of the high-pressure, conflict-driven spaces in which they typically occupy.

Originality/value
This research highlights the relevance of the setting in which child rehabilitation takes place and the potential role of natural environments in providing places and opportunities which support pro-social identity development and desistance for children.
Effects of grass functional diversity on invasion success by exotic grasses in Cerrado grasslands
Authors: Mazzochini Guilherme G. , Lira‐Martins Demétrius , de Barros Fernanda V. , Oliveira Ana C. C. , Xavier Rafael O. , Furtado Mariana N. , Verona Larissa S. , Viani Ricardo A. G. , Rowland Lucy , Oliveira Rafael S. 
Published: December 2023

Abstract

Invasive species pose significant challenges to successful restoration efforts worldwide. A strategy to reduce invasions is to establish communities consisting of species with varied ecological strategies. These strategies typically align along the conservative and plant size axes, and more recently, along a below‐ground collaboration axis. However, we lack understanding of how the diverse ecological strategies of Cerrado grass species, their combinations and their interactions with soil conditions can mitigate invasions.

Here, we investigated how native grass communities composed by species with different ecological strategies affect the invasion success in two soil types of abandoned pastures in the Cerrado. Specifically, we tested the hypothesis that greater above‐ and below‐ground functional diversity reduces exotic species invasion. We also evaluated whether the isolated effects of native species on invasion were positive or negative.

We installed an experiment with species richness ranging from zero to eight native grass species. In November 2019, we sowed species combinations to create communities composed by species with different ecological strategies. We quantified the above‐ground biomass of exotic species as a measure of invasion. To characterize the species ecological strategies, we measured five functional traits.

Functional diversity of maximum height and specific root length (SRL) had the highest predictive power; however, the most parsimonious model included only SRL diversity, which represents the collaboration axis. Native above‐ground biomass was also negatively related to exotic species biomass. Furthermore, invasion was greater in less stressful soil conditions but did not interact with diversity. The effect of native species varied from facilitation to competition, with the annual fast‐growing native species favouring invasion.

Synthesis and applications. Our results show that greater functional diversity of combined above‐ and below‐ground traits reduces invasion success, shedding light on an underexplored role of specific root length diversity. The competitive and facilitative effects of different native species highlight the need for careful selection of the species to be used in restoration programmes. Furthermore, the absence of interaction between diversity and soil types highlights the need for an integrated management of the functional composition and edaphic factors to increase resistance to invasion in these Neotropical grass communities.
Mechanism of action of anthocyanin on the detoxification of foodborne contaminants—A review of recent literature
Authors: Jiang Yan , Li Xusheng , Zhang Yulin , Wu Biyu , Li Yuxi , Tian Lingmin , Sun Jianxia , Bai Weibin 
Published: December 2023

AbstractFoodborne contaminants refer to substances that are present in food and threaten food safety. Due to the progress in detection technology and the rising concerns regarding public health, there has been a surge in research focusing on the dangers posed by foodborne contaminants. These studies aim to explore and implement strategies that are both safe and efficient in mitigating the associated risks. Anthocyanins, a class of flavonoids, are abundantly present in various plant species, such as blueberries, grapes, purple sweet potatoes, cherries, mulberries, and others. Numerous epidemiological and nutritional intervention studies have provided evidence indicating that the consumption of anthocyanins through dietary intake offers a range of protective effects against the detrimental impact of foodborne contaminants. The present study aims to differentiate between two distinct subclasses of foodborne contaminants: those that are generated during the processing of food and those that originate from the surrounding environment. Furthermore, the impact of anthocyanins on foodborne contaminants was also summarized based on a review of articles published within the last 10 years. However, further investigation is warranted regarding the mechanism by which anthocyanins target foodborne contaminants, as well as the potential impact of individual variations in response. Additionally, it is important to note that there is currently a dearth of clinical research examining the efficacy of anthocyanins as an intervention for mitigating the effects of foodborne pollutants. Thus, by exploring the detoxification effect and mechanism of anthocyanins on foodborne pollutants, this review thereby provides evidence, supporting the utilization of anthocyanin‐rich diets as a means to mitigate the detrimental effects of foodborne contaminants.
Elaboration of dimensional quality in 3D‐printed food: Key factors in process steps
Authors: Wen Yaxin , Che Quang Tuan , Wang Shaoyun , Park Hyun Jin , Kim Hyun Woo 
Published: December 2023

AbstractThree‐dimensional (3D) printing has been applied to produce food products with intricate and fancy shapes. Dimensional quality, such as dimensional stability, surface smoothness, shape fidelity, and resolution, are essential for the attractive appearance of 3D‐printed food. Various methods have been extensively studied and proposed to control the dimensional quality of printed foods, but few papers focused on comprehensively and deeply summarizing the key factors of the dimensional quality of printed products at each stage—before, during, and after printing—of the 3D printing process. Therefore, the effects of pretreatment, printing parameters and rheological properties, and cooking and storage on the dimensional quality of the printed foods are summarized, and solutions are also provided for improving the dimensional quality of the printed products at each step. Before printing, incorporating additives or applying physical, chemical, or biological pretreatments can improve the dimensional quality of carbohydrate‐based, protein‐based, or lipid‐based printed food. During printing, controlling the printing parameters and modifying the rheological properties of inks can affect the shape of printed products. Furthermore, post‐processing is essential for some printed foods. After printing, changing formulations, incorporating additives, and selecting post‐processing methods and conditions may help achieve the desired shape of 3D‐printed or 4D‐printed products during cooking. Additives help in the storage stability of printed food. Finally, various opportunities have been proposed to regulate the dimensional properties of 3D‐printed structures. This review provides detailed guidelines for researchers and users of 3D printers to produce various printed foods with the desired shapes and appearances.
Association between hyponatremia, inflammation, and mortality in patients undergoing peritoneal dialysis: A nationwide observations
Authors: Erdogan Bulent , Ata Naim , Caglayan Murat , Gözükara Melih Gaffar , Gemcioglu Emin , Sokmen Fevzi Coskun , Yilmaz Nuray , Celik Osman , Ayvali Mustafa Okan , Ulgu Mustafa Mahir , Birinci Suayip 
Published: December 2023

AbstractIntroductionHyponatremia is the most common electrolyte disorder often present in peritoneal dialysis (PD) patients. The aim of this retrospective study was to investigate the effect of hyponatremia on mortality in patients undergoing PD.MethodsThe health records of adult individuals with an inserted PD catheter identified via the centralized national e‐health database were used.ResultsThe mean age of the 846 patients included in the study was 52.48 years (±14.6). The mean sodium level was 136.51 mEq/L. Sodium levels <137 mEq/L were associated with higher death risk independent of comorbidities. There was a 0.821 times less reduction in mortality for each mEq /L increase in serum sodium.ConclusionOur study provides evidence that monitoring and adjusting serum sodium levels is crucial in managing PD patients with hyponatremia, as low serum sodium level was found to be a significant and independent predictor of mortality.