bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Liquid Organic Formulations on Productivity and Profitability of Mung-bean crop under Semi Arid Environment of Rajasthan
Authors: Yadav Seema , Meena B. R. , Meena Santosh Kr. , Singh Narpat , Yadav Rajesh 
Published: December 2023

Aims: The increasing cost and unavailability of fertilizers, poor soil health, growing ecological concern, consumer health problems and the government’s interest in promoting the organic farming have forced to try new methods of application of nutrients in the form of liquid organic formulations. Hence, the present investigation was aimed to know the effect of liquid organic formulations on productivity and profitability of mungbean crop under semi-arid environment of Rajasthan.
Methods: The field experiment was conducted at Agronomy farm, School of Agriculture, OPJS University Churu, Rajasthan. This experiment was laid out in a randomized block design with three replications, consist of twelve treatments namely Control, Water spray, Panchgavya (2 spray), Vermiwash (2 spray), Cow urine (2 spray), Matka khad (2 spray), Panchgavya + Vermiwash, Panchgavya + Cow urine, Panchgavya + Matka khad, Vermiwash + Cow urine, Vermiwash + Matka khad and Cow urine + Matka khad.
Results: The results revealed that independent two spray of panchgavya and spray of panchgavya+ vermiwash (one spray of each) resulted significantly higher crop growth attributes, yield attributes and yields as well as net returns of mungbean. The said treatments recorded highest grain yields (1128 and 1051 kg/ha), net return (55576 and 49361 Rs/ha) and befit cost ratio (2.30 and 2.07) which was significant over rest of the treatments. According to our findings independent two spray of panchgavya at 25 and 45 DAS and combined spray of panchgavya + vermiwash (one spray of each) is recommended for higher productivity with more economic returns.
Drought Tolerance in Soybean (Glycine max L. Merr.) Genotypes during the Flowering Stage of Development
Authors: Puobi R. E. , Asare A. T. , Otwe E. P. , Galyuon I. K. A. 
Published: December 2023

Aims: To access the responses of 22 soybean genotypes under drought stress during the flowering stage of development.
Study Design: A completely randomized experimental design (CRD) was adopted in this study. Five seeds of each of the 22 soybean genotypes were planted in 12-liter (L) plastic buckets (with holes at the bottom) containing sandy loam soil. There was one genotype per pot with three replications. The setup was repeated to represent experimental (drought-stressed (DS) and control (well-watered (WW) groups.
Place and Duration of Study: Teaching and Research Farm of the School of Agriculture, College of Agriculture and Natural Sciences, University of Cape Coast, Cape Coast, Ghana in 2019.
Methodology: Twenty-one exotic soybean genotypes and a local variety were assessed for their responses to drought stress at the flowering stage of development using pot experiment in the greenhouse. One group (experimental) was exposed to drought stress by withholding water for 15 days whilst the other group (control) was watered regularly at three-day intervals. Data collected were the number of leaves, plant height, stem girth, leaf area, and number of flowers, at 5, 10, and 15 days after treatment (DAT) and relative leaf water content at 15 DAT. The number of days to permanent wilting of the genotypes was also recorded.
Results: Drought stress reduced the number of leaves and plant height significantly (P-values = 0.033, 0.000) and (P-values = 0.004, 0.000) at 10 and 15 days after drought treatment respectively. Also, stem girth, leaf area, and number of flowers were significantly reduced at all sampling dates (P-value = 0.002, 0.000, 0.000), (P-values = 0.004, 0.000, 0.000) and (P-values = 0.009, 0.000, 0.000) respectively. At 15 DAT, drought significantly (P < 0.001) reduced relative leaf water content. Genotypes TGX-1989-11F and TGX-1987-62F were the first and last to wilt at 7 days and 16 days after rewatering respectively.
Conclusion: The pot screening method revealed that the number of leaves, plant height, stem girth, leaf area, number of flowers, relative leaf water content, and days to permanent wilting differed significantly (P = 0.05) at 15 days of drought exposure.
Enabling High Throughput Kinetic Experimentation by Using Flow as a Differential Kinetic Technique**
Authors: Lennon Gavin , Dingwall Paul 
Published: December 2023

AbstractKinetic data is most commonly collected through the generation of time‐series data under either batch or flow conditions. Existing methods to generate kinetic data in flow collect integral data (concentration over time) only. Here, we report a method for the rapid and direct collection of differential kinetic data (direct measurement of rate) in flow by performing a series of instantaneous rate measurements on sequential small‐scale reactions. This technique decouples the time required to generate a full kinetic profile from the time required for a reaction to reach completion, enabling high throughput kinetic experimentation. In addition, comparison of kinetic profiles constructed at different residence times allows the robustness, or stability, of homogeneously catalysed reactions to be interrogated. This approach makes use of a segmented flow platform which was shown to quantitatively reproduce batch kinetic data. The proline mediated aldol reaction was chosen as a model reaction to perform a high throughput kinetic screen of 216 kinetic profiles in 90 hours, one every 25 minutes, which would have taken an estimated continuous 3500 hours in batch, an almost 40‐fold increase in experimental throughput matched by a corresponding reduction in material consumption.
Photoactivatable aggregation‐induced emission luminogens based on photodehydrogenation reactions for biomedical applications
Authors: You Yuanyuan , Tang Chengwei , Lin Songling , Zeng Delong , Cong Yanguang , Wang Dong , Chen Xiaohui 
Published: December 2023

AbstractThe development of photoactivatable aggregation‐induced emission (AIE) probes is one of the hotspots for bioimaging and imaging‐guided precise disease therapy due to the distinct advantages of high spatiotemporal resolution, precise spatiotemporal controllability, and noninvasiveness of light. To design and develop novel photoactivatable AIE probes, functional groups based on photodehydrogenation reaction mechanisms are combined with the AIE‐active skeleton. Here, the recent progress in biomedical applications of photoactivatable AIE probes based on photocyclodehydrogenation and photo‐oxidative dehydrogenation reactions are summarized briefly. Moreover, the outlook for photoactivatable AIE probes is discussed to aim at promoting innovative research in biomedical applications.
Unlocking same‐sign CPL: solvent effects on spectral form and racemisation kinetics in nine‐coordinate chiral europium(III) complexes
Authors: De Rosa Davide F. , Starck Matthieu , Parker David , Pal Robert 
Published: December 2023

AbstractUnderstanding the factors that shape the circularly polarised luminescence (CPL) emission profiles of europium(III)‐based CPL emitters to have specific sign properties, e. g. monosignate individual CPL transitions, is key to design novel complexes for applications ranging from advanced security inks to bio‐probes for live cell imaging. In order to correlate structure and spectral characteristics, a photophysical and kinetic investigation has been conducted on a series of coordinatively saturated nine‐coordinate europium(III) systems based on 1,4,7‐triazacyclononane. We highlight that lanthanide emission is sensitive to changes in the ligand field by showing the linear dependence of total emission intensity ratios as a function of solvent polarity, for europium(III) complexes displaying an internal charge transfer (ICT) excited state. This sensitivity increases by a factor of 20 when studying changes in CPL spectra, rendering these complexes accurate probes of local polarity. Solvent polarity, solvent‐specific effects, and the nature of the chromophores’ coordinating donor atoms strongly influence the kinetic stability of europium(III) complexes with respect to enantiomer interconversion. Notably, we show that the choice of donor groups to coordinating to europium(III) and the nature and polarity of the solvent affects the rate of racemisation, leading to systems with very long half‐lives at room temperature in non‐polar media.
A study of pod constriction in a peanut population with mixed wild and cultivated genetics
Authors: Ballén‐Taborda Carolina , Maharjan Namrata , Hopkins Mark , Guimarães Larissa Arrais , Lindsey Duncan , Bertioli David J. , Leal‐Bertioli Soraya C. M. 
Published: December 2023

AbstractWild relatives comprise a diverse genetic source from which to introduce beneficial alleles for peanut breeding. However, when using wild species for breeding, unadapted agronomic characteristics are often co‐inherited along with favorable traits. Previously, an advanced backcross population was developed from a cross between Arachis hypogaea and the wild‐derived induced allotetraploid (Arachis batizocoi × Arachis stenosperma)4x to incorporate nematode resistance genes into elite peanut. We observed additional wild alleles unintentionally inherited throughout the genome, possibly causing variation in several pod and seed characteristics. To identify the wild introgressions controlling the variation in pod constriction (PC), a critical trait for peanut's acceptability and marketability, we performed an association analysis using 419 SNPs and phenotypic data of 72 BC3F2/3 families. An introgression on the top of chromosome B08 (pod constriction‐quantitative trait locus [PC‐QTL], 3.7 Mbp) derived from A. batizocoi was found to be controlling 47.3% of the PC variation. To confirm the PC‐QTL, six BC3F4 families harboring the wild loci in a homozygous or heterozygous state were selected and used for segregation analysis. All progenies from the backcross families carrying the homozygous allele had severely constricted pods, whereas progenies from families with the heterozygous allele were segregated for PC. Finally, analyses using end‐point genotyping with four linked SNP assays confirmed the association of the PC‐QTL with PC. The present work studied PC and developed DNA markers to assist the selection against constricted pods while retaining the new and beneficial wild‐derived genes.
Synthesis and reactivity of a dialkyl‐2H‐1,2‐phosphasiliren‐3‐olate
Authors: Yan Liping , Wu Lifang , Zhao Yunqing , Zhang Rong , Qi Fan , Wang Liliang , Li Zhifang 
Published: December 2023

AbstractA heterocycle containing phosphorus, known as dialkyl‐2H‐1,2‐phosphasiliren‐3‐olate 2, is synthesized through the reaction of dialkylsilylene 1 and sodium phosphaethynolate (NaOCP) in a high yield at ambient conditions. The structure of 2 is determined by single‐crystal X‐ray diffraction and multinuclear NMR spectroscopy. The theoretical studies are identified two nucleophilic centres located on the phosphorus (P) and oxygen (O) atoms, respectively. According to WBIs and the crystal characterization analyses, both the C−P and C−O bonds in the C−Si‐P three‐membered ring have significant double bond character. Reactions involving R3SiCl and Me2SO4 with 2 at room temperature are also conducted at room temperature. The nucleophilic substitution reaction can also occur on oxygen atom of 2, and yield ring‐retaining products 3 and 4 a–4 c, respectively. When acyl chlorides are employed as electrophiles, the derivatives of (silylmethylidyne)phosphane, 6 a–6 c, are produced as a result of the substitution of the oxygen atom.
Application of a capillary electrophoresis–mass spectrometry metabolomics workflow in zebrafish larvae reveals new effects of cortisol
Authors: van Mever Marlien , Mamani‐Huanca Maricruz , Faught Erin , López‐Gonzálvez Ángeles , Hankemeier Thomas , Barbas Coral , Schaaf Marcel J. M. , Ramautar Rawi 
Published: December 2023

AbstractIn contemporary biomedical research, the zebrafish (Danio rerio) is increasingly considered a model system, as zebrafish embryos and larvae can (potentially) fill the gap between cultured cells and mammalian animal models, because they can be obtained in large numbers, are small and can easily be manipulated genetically. Given that capillary electrophoresis–mass spectrometry (CE–MS) is a useful analytical separation technique for the analysis of polar ionogenic metabolites in biomass‐limited samples, the aim of this study was to develop and assess a CE–MS‐based analytical workflow for the profiling of (endogenous) metabolites in extracts from individual zebrafish larvae and pools of small numbers of larvae. The developed CE–MS workflow was used to profile metabolites in extracts from pools of 1, 2, 4, 8, 12, 16, 20, and 40 zebrafish larvae. For six selected endogenous metabolites, a linear response (R2 > 0.98) for peak areas was obtained in extracts from these pools. The repeatability was satisfactory, with inter‐day relative standard deviation values for peak area of 9.4%–17.7% for biological replicates (n = 3 over 3 days). Furthermore, the method allowed the analysis of over 70 endogenous metabolites in a pool of 12 zebrafish larvae, and 29 endogenous metabolites in an extract from only 1 zebrafish larva. Finally, we applied the optimized CE–MS workflow to identify potential novel targets of the mineralocorticoid receptor in mediating the effects of cortisol.
Functional decline during the COVID‐19 pandemic among U.S. military veterans: Results from the National Health and Resilience in Veterans Study
Authors: Morse Jessica L. , Fischer Ian C. , Na Peter J. , Afari Niloofar , Pietrzak Robert H. 
Published: December 2023

AbstractObjectivesThe coronavirus disease‐2019 pandemic has contributed to widespread social and economic stressors, along with substantial health problems, including loss of life. To date, however, relatively few studies have examined the prevalence and correlates of declines in mental and physical functioning in U.S. military veterans, an older and potentially vulnerable segment of the U.S. adult population.MethodsData were analyzed from the 2019–2020 National Health and Resilience in Veterans Study, a nationally representative, longitudinal study of 3078 veterans. Veterans were surveyed prior to the pandemic (pre‐pandemic) and 1 year later during the height of the pandemic (peri‐pandemic). Multivariable analyses were conducted to identify risk and protective variables associated with pre‐to‐peri pandemic declines in self‐reported physical and mental functioning.ResultsThe prevalence of veterans who experienced functional decline (≥0.5 standard deviation reductions) pre‐to‐peri‐pandemic was 18.1% (N = 541) for physical functioning and 18.3% (N = 547) for mental functioning. Older age, greater adverse childhood experiences (ACEs), and pandemic‐related posttraumatic stress symptoms were the strongest correlates of physical functional decline, while greater ACEs, loneliness, pandemic‐related posttraumatic and social restriction stress symptoms, and lower protective psychosocial characteristics were the strongest correlates of mental functional decline.ConclusionsAlthough the majority of U.S. Veterans showed functional maintenance or improvement 1 year into the pandemic, nearly one‐in‐five experienced a decline in physical or mental functioning. Results could help inform identification of veterans who may be at risk for functional decline during large‐magnitude stressors, such as national or global pandemics.
Fractionation and physicochemical characterization of dietary fiber of kenaf (Hibiscus cannabinus L.) seed
Authors: Nevara Gita Addelia , Muhammad Sharifah Kharidah Syed , Zawawi Norhasnida , Mustapha Nor Afizah , Karim Roselina 
Published: December 2023

AbstractBACKGROUNDKenaf seeds are underutilized kenaf plant by‐products, containing essential nutrients including dietary fiber (DF), which can be potentially utilized as food ingredients. The present study aimed to evaluate the physicochemical characteristics of kenaf seed fiber fractions extracted from kenaf seed.RESULTSDefatted kenaf seed powder yielded four DF fractions: alkali‐soluble hemicellulose (146.4 g kg−1), calcium‐bound pectin (10.3 g kg−1) and acid‐soluble pectin (25.4 g kg−1) made up the soluble fibre fraction, whereas cellulose (202.2 g kg−1) comprised the insoluble fraction. All fractions were evaluated for their physicochemical properties. The DF fractions contained glucose, mannose, xylose and arabinose, and a small amount of uronic acid (1.2–2.7 g kg−1). The isolated pectin fractions had a low degree of esterification (14–30%). All the isolated DF fractions had high average molecular weights ranging from 0.3 to 4.3 × 106 g mol−1. X‐ray diffractogram analysis revealed that the fractions consisted mainly of an amorphous structure with a relative crystallinity ranging from 31.6% to 44.1%. The Fourier‐transform infrared spectroscopy spectrum of kenaf seed and its DF fractions showed typical absorption of polysaccharides, with the presence of hydroxyl, carboxyl, acetyl and methyl groups. Scanning electron microscopy analysis demonstrated that the raw material with the rigid structure resulted in soluble and insoluble DF fractions with more fragile and fibrous appearances, respectively. The soluble DF demonstrated greater flowability and compressibility than the insoluble fractions.CONCLUSIONThese findings provide novel information on the DF fractions of kenaf seeds, which could be used as a potential new DF for the food industry. © 2023 Society of Chemical Industry.
Recent developments in stretchable and flexible tactile sensors towards piezoresistive systems: A review
Authors: Saxena Akshay , Patra Karali 
Published: December 2023

AbstractStretchable and flexible piezoresistive sensors (SFPSs) can detect mechanical stimuli in terms of electrical response and provide adaptability to use with complex surfaces, whether stationary or moving. Its stretchable and flexible nature makes it ideal for detecting large strains, localized pressure, bending, and twisting. SFPSs can detect pressure and strain in a broad range. SFPSs have ease of manufacturing, high sensitivity, better durability, easy processing, and economic development. These qualities of SFPSs can open a wide range of application possibilities, such as healthcare, human motion detection, a safe environment to interact with robots, automation, and soft robotics. The discussion in this article starts from the sensing mechanism, design development over the years, a variety of materials used for substrates and to provide conductivity to the sensors, fabrication processes explored and developed, enhancement in the performance characteristics, to have future directions. Over the last decades, exponential development has occurred in SFPSs systems based on design mechanisms, materials used, and fabrication techniques, even though several technological and design challenges remain undetermined and bear decisive interdisciplinary intervention to address them.
Non‐conditioned cord blood transplantation for infection control in athymic CHARGE syndrome
Authors: Sonoda Motoshi , Ishimura Masataka , Inoue Hirosuke , Eguchi Katsuhide , Ochiai Masayuki , Sakai Yasunari , Doi Takehiko , Suzuki Kyoko , Inoue Takeshi , Mizukami Tomoyuki , Nakamura Kimitoshi , Takada Hidetoshi , Ohga Shouichi 
Published: December 2023

AbstractObjectiveCHARGE syndrome is a congenital malformation syndrome caused by heterozygous mutations in the CHD7 gene. Severe combined immunodeficiency (SCID) arises from congenital athymia called CHARGE/complete DiGeorge syndrome. While cultured thymus tissue implantation (CTTI) provides an immunological cure, hematopoietic cell transplantation (HCT) is an alternative option for immuno‐reconstitution of affected infants. We aimed to clarify the clinical outcomes of patients with athymic CHARGE syndrome after HCT.MethodsWe studied the immunological reconstitution and outcomes of four patients who received non‐conditioned unrelated donor cord blood transplantation (CBT) at Kyushu University Hospital from 2007 to 2022. The posttransplant outcomes were compared with the outcomes of eight reported patients.ResultsFour index cases received CBT 70–144 days after birth and had no higher than grade II acute graft‐versus‐host disease. One infant was the first newborn‐screened athymic case in Japan. They achieved more than 500/μL naïve T cells with balanced repertoire 1 month post transplant, and survived more than 12 months with home care. Twelve patients including the index cases received HCT at a median 106 days after birth (range: 70–195 days). One‐year overall survival rate was significantly higher in patients who underwent non‐conditioned HCT than in those who received conditioned HCT (100% vs. 37.5%, p = .02). Nine patients died, and the major cause of death was cardiopulmonary failure.ConclusionsAthymic infants achieved a prompt reconstitution of non‐skewing naïve T cells after non‐conditioned CBT that led to home care in infancy without significant infections. Non‐conditioned CBT is a useful bridging therapy for newborn‐screened cases toward an immunological cure by CTTI.
Colorectal cancer survivors' experiences and views of shared and telehealth models of survivorship care: A qualitative study
Authors: Gore Claire , Lisy Karolina , O’Callaghan Clare , Wood Colin , Emery Jon , Martin Andrew , De Abreu Lourenco Richard , Schofield Penelope , Jefford Michael 
Published: December 2023

AbstractObjectivesThe number of colorectal cancer (CRC) survivors is increasing and current models of survivorship care are unsustainable. There is a drive to implement alternative models of care including shared care between general practitioners (GPs) and hospital‐based providers. The primary objective of this study was to explore perspectives on facilitators and barriers to shared care. The secondary objective was to explore experiences of telehealth‐delivered care.MethodQualitative data were collected via semi‐structured interviews with participants in the Shared Care for Colorectal Cancer Survivors (SCORE) randomised controlled trial. Interviews explored patient experiences of usual and shared survivorship care during the SCORE trial. In response to the COVID pandemic, participant experiences of telehealth appointments were also explored. Interviews were recorded and transcribed for thematic analysis.ResultsTwenty survivors of CRC were interviewed with an even number in the shared and usual care arms; 14 (70%) were male. Facilitators to shared care included: good relationships with GPs; convenience of GPs; good communication between providers; desire to reduce public health system pressures. Barriers included: poor communication between clinicians; inaccessibility of GPs; beliefs about GP capacity; and a preference for follow‐up care with the hospital after positive treatment experiences. Participants also commonly expressed a preference for telehealth‐based follow‐up when there was no need for a clinical examination.ConclusionsThis is one of few studies that have explored patient experiences with shared and telehealth‐based survivorship care. Findings can guide the implementation of these models, particularly around care coordination, communication, preparation, and personalised pathways of care.