bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of the Severe Malaria “Champions Program” on the Management of Severe Malaria Cases in 12 Hospitals of the North and Far North Regions of Cameroon
Authors: Tchinda Meli Eric , Bernard Yves-Marie , Ateba Joël Marcellin , Tchoutang Landry , Mouliom Abas , Ciceron Annie Coriolan , Mostel Jadmin , Tchadjeu Christophe , Palata Olivier , Wirngo Mohamadu , Fofana Aissata , Barat Lawrence M. 
Published: February 2024

ABSTRACT.
Malaria remains a main cause of morbidity and mortality in Cameroon. Since 2021, the U.S. President’s Malaria Initiative Impact Malaria Project has supported the National Malaria Control Program to develop the Champions program in two northern regions. We assessed this program’s preliminary effectiveness on the performance of hospitals in the management of severe malaria and reduction of malaria-related deaths. We conducted a secondary analysis of Outreach Training and Supportive Supervision (OTSS) data from four rounds (one round pre-Champions program and three rounds post-Champions program and 2020–2022 malaria-related mortality data for 12 hospitals). Using linear regressions, we measured changes in hospital readiness and competency of health workers in the management of severe malaria between baseline and subsequent rounds. There were statistically significant improvements in overall management of severe malaria scores in post-Champions OTSS rounds, with post-Champions round 3 exhibiting an increase of +14% (P = 0.013) over baseline. Overall health facility readiness scores exhibited an increase of +7% (P = 0.006) from baseline to post-Champions round 3. There were no statistically significant findings associated with providing the right treatment, as nearly all patients hospitalized with severe malaria were treated with a recommended severe malaria treatment. Reported inpatient malaria deaths and case fatality rates trended downward from 2020 to 2022, but these differences were not statistically significant. The Champions program resulted in significant improvements in quality of inpatient care for severe malaria. The downward trends in malaria deaths and case fatality rate will require further monitoring to determine whether the Champions program is having the desired impact of reducing inpatient deaths from malaria.
Utility of a targeted next-generation sequencing-based genetic screening panel in patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis syndrome
Authors: Miray Kışla Ekinci Rabia , Anlaş Özlem , Özalp Özge 
Published: February 2024

Objectives: This study aims to investigate a genetic panel in patients with periodic fever, aphthous stomatitis, pharyngitis, and adenitis (PFAPA) syndrome and examine its performance for an accurate differential diagnosis.
Patients and methods: Between January 2021 and January 2022, a total of 104 children with PFAPA syndrome (63 males, 41 females; mean age: 4.8±2.3 years; range, 1.2 to 8.9 years) were retrospectively analyzed. Next-generation sequencing test was performed using a custom QIAGEN- QIAseq™ Targeted DNA Panel which includes six genes namely ELANE, LPIN2, MEFV, MVK, NLRP3, and TNFRSF1A.
Results: Of 104 patients, 38 (36.5%) had variants in the genetic panel. The most common variants were found in the MEFV gene (n=35, 33.6%), the most frequent genotype was E148Q heterozygosity (n=16). Four and two patients were eventually diagnosed with Familial Mediterranean fever (FMF) and hyperimmunoglobulin D syndrome (HIDS), since they had confirmative biallelic pathogenic in the MEFV and MVK genes, respectively.
Conclusion: A genetic panel, including MEFV and MVK genes, may be useful in patients, clinically resembling PFAPA, since they may have HIDS or FMF, but lack typical features of the exact disease. Nonetheless, we believe that distinct genetic panels should be developed for different populations.
A clinical analysis of hemophagocytic syndrome secondary to autoimmune diseases
Authors: Liu Yang , Li Qian , Su Yazhen , Che Guozhu , Liu Ying , Qiao Pengyan , Liu Sumiao , Xu Ke 
Published: February 2024

Objectives: This study aimed to analyze the differences of etiologies and clinical features between patients with autoimmune-associated hemophagocytic syndrome (AAHS) and those with other underlying diseases of hemophagocytic syndrome (HPS).
Patients and methods: The retrospective study was performed with 130 HPS patients (70 males, 60 females; mean age: 50.4±18.1 years; range, 13 to 85 years) between January 1st, 2011, and April 1st, 2022. The patients fulfilled at least five of the eight criteria proposed by the Histiocytosis Society in 2004. The underlying diseases related to HPS were divided into four categories: autoimmune, infection, malignancy and idiopathic diseases. And the clinical manifestations, laboratory examinations, treatments, and prognosis were analyzed respectively.
Results: Nineteen (14.6%) patients had AAHS, 45 (34.6%) had infection-associated HPS, 57 (43.8%) had malignancy-associated HPS, and nine (6.9%) had idiopathic HPS. The most common symptoms of HPS were unremitting fever in 123 (94.6%) of 130 patients and splenomegaly in 92 (70.8%). All patients manifested a decline of at least two lineages of hematopoietic cells. The absolute values of T cells and B cells of AAHS were significantly higher than that of malignancy-associated HPS. The levels of soluble CD25 (interleukin-2 receptor) of AAHS were the lowest among all-cause HPS (p<0.05). The all-cause mortality rate of hospitalized patients with HPS was 46.2%. The patients with AAHS had a better prognosis compared to other etiologies (odds ratio [OR]=0.091, 95% confidence interval [CI]: 0.011-0.775, p=0.028). Epstein-Barr virus infection (OR=4.761, 95% CI: 1.619-14.004, p=0.005) and pulmonary involvement (OR=4.555 95% CI: 1.524-13.609, p=0.007) were independent predictors of poor outcome in HPS. Thrombocytopenia (OR=0.978, 95% CI: 0.968-0.999, p=0.040) had a boundary effect on prognosis.
Conclusion: Patients with HPS secondary to autoimmune disease have better outcomes compared to patients complicated with Epstein-Barr virus infection or pulmonary involvement.
Independent semitotal domination in graphs
Authors: Padmavathi S. V. , Manju J. Sabari 
Published: February 2024

In this paper a slight different parameter, independent semitotal domination number- git2(G) is introduced. This parameter lies between i(G) and b0(G) of a graph. We initiate a study on this parameter git2(G). We construct graphs for prescribed gt(G) and git2(G). Also we determine bounds for git2 value of graphs.
Trabalho, estresse e pandemia de Covid-19: um estudo com docentes do ensino superior brasileiro
Authors: Martins Júlia Tomedi , Bernardes Mônica , Girardelo Tainá , Gonçalves Júlia 
Published: February 2024

Diferentes fatores de risco psicossociais antecedem o estresse no trabalho e comprometem a saúde dos trabalhadores. Esta pesquisa identificou características do trabalho de docentes do ensino superior brasileiros na pandemia de Covid-19, capazes de influenciar no desenvolvimento do estresse. Realizou-se uma pesquisa quantitativa com 203 docentes de instituições públicas e privadas de diferentes estados do Brasil. Aplicou-se um questionário de dados socioprofissionais e a Job Stress Scale (versão adaptada ao português). Aspectos do trabalho dos participantes se destacaram, como exigência de trabalhar intensamente, com rapidez, necessidade de uso de habilidades e conhecimentos específicos para o desenvolvimento de suas tarefas. Os participantes possuem percepção de alta demanda de trabalho (60%), alto controle e autonomia em suas tarefas (64%) e alto apoio social (53%). Houve percepção de aumento da carga de trabalho durante a pandemia (68%). A análise possibilitou incluir 39% da amostra no quadrante ativo do modelo teórico utilizado. O trabalho ativo pode ser indicativo de que, apesar das características e demandas do trabalho docente na pandemia, o alto controle sobre suas atividades laborais, aliado ao apoio social podem atenuar fatores que levam ao estresse no trabalho. Os achados desta pesquisa permitem refletir e subsidiar práticas que proporcionem saúde aos docentes.
Floristic and structural distinctness of monodominant Gilbertiodendron dewevrei forest in the western Congo Basin
Authors: Heimpel Ellen , Ahrends Antje , Dexter Kyle G. , Hall Jefferson S. , Mamboueni Josérald , Medjibe Vincent P. , Morgan David , Sanz Crickette , Harris David J. 
Published: February 2024

Background and aims– The forests of the Congo Basin contain high levels of biodiversity, and are globally important for carbon storage. In order to design effective conservation strategies, and to accurately model carbon stocks, a fine-scale understanding of the different forest types that make up this forest block is needed. MonodominantGilbertiodendron dewevreiforest covers large areas of the Congo Basin, but it is currently unclear whether it is sufficiently distinct from adjacent mixed terre firme forest to warrant separate treatment for conservation planning and carbon calculations. This study aimed to compare the structure and diversity of monodominant and mixed forest, and ask whether there is a unique vascular plant community associated withG. dewevreiforest.Material and methods– We utilised a combination of plot data and herbarium specimens collected in the Sangha Trinational (a network of protect areas in Cameroon, Central African Republic, and the Republic of Congo). Plot inventories were used to compareG. dewevreiforest and mixed forest for stem density, basal area, above ground biomass, stem size distribution, species diversity, and species composition. In addition, a database of 3,557 herbarium specimens was used to identify species of vascular plant that are associated withG. dewevreiforest.Key results–Gilbertiodendron dewevreiforest is distinct in both structure and species composition from mixed forest.Gilbertiodendron dewevreiforest has a lower stem number (of trees ≥ 10 cm), but a greater proportion of larger trees (&gt; 70 cm), suggesting higher carbon stocks. The species composition is distinct from mixed forest, with 56 species of vascular plant significantly associated withG. dewevreiforest.Conclusion– MonodominantG. dewevreiforest in the Sangha Trinational is both compositionally and structurally distinct from mixed forest. We therefore recommend this forest type be considered separately from mixed forest for conservation planning and carbon stock calculations.
Impact of Disulfide/Thiol Redox Couple on Pulse Wave Velocity in Patients with Normal Coronary Angiography
Authors: Akyol Selahattin , Harbalıoğlu Hazar , Gür Mustafa , Erel Özcan , Çelik Hakim 
Published: February 2024

Introduction: The oxidized thiol/disulfide couple has been investigated and reported as a potential risk factor for cardiovascular diseases. Additionally, an increased pulse wave velocity has been identified as a predictor of cardiovascular events.
Patients and Methods: 262 patients were included in our study. Native and total thiol levels, total disulfide levels, disulfide per total thiol ratios, native thiol per total thiol ratios, and disulfide per native thiol level ratios were calculated.
Results: Patients were divided into Pulse Wave Velocity (PWV) low and PWV high groups. Native and total thiol levels were higher in PWV low group compared to PWV high group (p< 0.001 for both). The median disulfide value was higher in PWV high group (p= 0.002). Disulfide per native thiol and disulfide per total thiol ratio values were higher in PWV high group (p< 0.001). Native thiol per total thiol ratios were higher in the PWV-low group (p< 0.001).
Conclusion: The disulfide/native thiol pathway may be an indicator for predicting future atherosclerotic cardiovascular events.
Clinical Characteristics and in-Hospital Outcomes of Patients Undergoing Left Atrial Appendage Closure
Authors: Zeren Gönül , Can Fatma , Sungur Mustafa Azmi , Yılmaz Şahin , Karabay Can Yücel 
Published: February 2024

Introduction: Percutaneous left atrial appendage closure (LAAC) is considered in patients with non-valvular atrial fibrillation (AF) who cannot receive long-term anticoagulant therapy or who experience thromboembolism despite anticoagulant therapy. The structural feature of the left atrial appendage (LAA) and high variability of the clinical features of the patients endorse the difficulty of the procedure. In this study, it was aimed to present our single-center LAAC experience and in-hospital follow-up results of the patients.
Patients and Methods: Patients who had undergone LAAC in our cardiology clinic between 2017 and 2022 were included in the study retrospectively. All clinical, laboratory and imaging characteristics of the patients and in-hospital follow-up results were evaluated.
Results: Median age of 29 patients included in the study was 78 years (65-82, IQR= 25-75) and 17 were males (58.6%). Median score of CHA2 DS2 -VASc was 4 (4-6, IQR= 25-75). In addition, median value of the HASBLED score was 3 (3-4, IQR= 25-75). The rate of complete closure, minor bleeding during the procedure, and pericardial tamponade were 27 (93.1%), 1 (3.4%), and 1 (3.4%) respectively, and the device was dislocated immediately after the procedure in one patient (3.4%). The most common type of LAA appendix was chicken wings 15 (51.7%).
Conclusion: Success rate of the LAAC procedure was high in this single-center study conducted in our country with a relatively high number of patients.
Pengelupasan Kulit Batang dan Penggunaan Zat Pengatur Tumbuh (ZPT) pada Stek Bugenvil (Bougainvillea spectabilis Willd.)
Authors: Puspitawati Mutiara Dewi , Barokah Nurfitriyani 
Published: February 2024

Pengelupasan kulit batang dan pemberian ZPT merupakan salah satu alternatif untuk meningkatkan keberhasilan stek bugenvil. Tujuan penelitian adalah untuk mengetahui tingkat keberhasilan dan kecepatan pertumbuhan stek bugenvil dengan perlakuan pengelupasan kulit batang dan pemberian berbagai ZPT. Penelitian dilakukan pada bulan Maret hingga Juli 2020 di Kebun Percobaan Universitas Trilogi, Jakarta Selatan. Penelitian ini menggunakan Rancangan Acak Kelompok Split-Plot dua faktor, yaitu faktor pengelupasan (pengelupasan dan tanpa pengelupasan) dan pemberian berbagai ZPT (kontrol, Rootone F 10 g L-1, sari bawang merah 200 g L-1, sari tauge 200 g L-1, dan air kelapa muda). Hasil penelitian menunjukkan kombinasi perlakuan pengelupasan kulit batang dengan perendaman sari bawang merah mampu meningkatkan persentase tumbuh stek bugenvil pink (Bougainvillea spectabilis Willd.) hingga 87% dibandingkan dengan perendaman Rootone F. Perlakuan pengelupasan tanpa pemberian berbagai sumber ZPT dan perlakuan tanpa pengelupasan dengan perendaman sari bawang merah memberikan waktu muncul tunas tercepat yaitu 10 HST. Perlakuan pengelupasan batang mampu meningkatkan jumlah tunas dan jumlah daun pada stek bougenville. Pemberian berbagai macam ZPT (dengan perlakuan tunggal) mampu meningkatkan jumlah dauh, jumlah tunas dan panjang tunas pada stek bougenville.
دراسة التأثير التأزري للمستخلص الايثانولي و الميثانولي لأوراق نبات الشيح والهجليج مع المضادات الحيوية علي بكتيريا Klebsiella pneumoniae. .Staphylococcus aureus ,
Authors: دلال يونس  , عبدالقادر الزين  
Published: February 2024

تم في هذا البحت دراسة العلاقة التفاعلية بين المستخلص الايثانولي والميثانولي لأوراق نبات الشيح والهجليج ,Artemisia Balanites بتركيز 100% وبعض المضادات الحيوية شائعة الاستخدام في تأثيرها علي نمط مقاومته لبكتيريا pneumoniae. Kو S. aureus وأظهرت النتائج أن المستخلص (الايثانولي و الميثانولي ) لأوراق نبات الشيح كان ذو تفاعل تآزري مع المضادات الحيوية (CTX30-AUG30)علي البكتيريا Staphylococcus aureus، Klebsiella pneumoniae.وكانت نتائج التفاعل تعادلية مع باقي مضادات الحيوية .
Aportación del formato talk show y documental en el relato de la violencia machista. La denuncia televisada de Ana Orantes y Rocío Carrasco
Authors: Bernal Triviño Ana 
Published: February 2024

Los medios de comunicación, según la ley española 1/2004, tienen la recomendación de sensibilizar ante la violencia de género. Entre los diversos géneros periodísticos, la noticia y el reportaje son las opciones más consolidadas pero la televisión, como una de las opciones más vistas entre la población, permite desarrollar otros formatos para el relato de la violencia de género de gran alcance. A través de dos casos mediáticos, con la denuncia televisada de Ana Orantes y Rocío Carrasco, se realiza un análisis de la aportación de los formatos de talk show y documental seriado con el objetivo de detectar sus diferencias, semejanzas e impacto social en la cobertura de la violencia de género. El estudio concluye que estos formatos televisivos fueron válidos para realizar un relato más personal de esta violencia, profundizar en experiencias y tener más impacto social, hasta ser punto de partida para adoptar medidas políticas.
КЫРГЫЗ МУЗЫКАЛЫК ФОЛЬКЛОРУНУН БАШАТЫ
Authors: Джумабаев Бакай , Баякова Айкан 
Published: February 2024

Кыргыздардын жашоо үчүн күрөшүүдө, калк сыпатында сакталып калышы, өздүк маданияты менен жанаша жашаган элдердин ичинен ордун табуусунда. Алсак, өзбек, казак, түркмөн элдеринин оозеки жана улуу кытай жазма маалыматында Орто Азия элдеринин эң байыркыларынын бири, түрк урууларынын арасынан өзгөчөсү деп аталбаса керек эле. Кыргыздар көчмөн турмушта жашап өздөрүнүн каада-салт, үрп-адаты жашоо тиричилиги географиялык абалынын негизинде өзүнүн жалпы маданияты калыптанып өсүп өнүгүп – келген эл. Ал эми музыкалык маданияты элибиздин жашап өткөн тарыхый мезгилинде түрдүү жанрларды өз ичине камтып, уламдан улам байытып олтуруп, коңушу элдердин ээсине дүрбөлөң маданияты менен эсте калып бүгүнкү деңгээлине жеткен. Андыктан кыргыз маданиятынын жазма булактарга өткөнгө чейинки доорун фольклор менен байлоо туура эле болот. Фольклор - эл чыгармачылыгы жөнүндөгү илим. Фольклористикада калайык жараткан (оозеки көркөм чыгарма, ыр, музыка, бий, драма жана башка) коллективдүү чыгармачылык изилденет. Кыргыз фольклористикасынын изилдениши, анын тарыхы совет доорунан башталат. Бул макалада кыргыз фольклористтеринин алгачкы изилдөөлөрү, анда элдик музыканын табияты, жанрлары жана ладдык өзгөчөлүктөрү баяндалып кыргыз фольклорунун тарыхын изилдөөчү фольклористтердин баалуу эмгектеринин маани-маңызы чечмеленет.
Design Basis Document / Owner’s Technical Specification for Nitrate Salt Systems in CSP Projects
Authors: Kelly Bruce , Imponenti Luca , Sambor Thomas , Bollinger Benjamin 
Published: February 2024

Work has begun on a Design Basis Document / Owner’s Technical Specification for parabolic trough and central receiver power plants using nitrate salt as the heat transport fluid and the thermal storage medium. A principal topic of recent interest is the failures of the hot salt tanks in central receiver projects. The paper outlines a hypothesis for the source of the failures, and discusses a range of possible solutions.
Partial Patellar Tendon Tears in Athletes: A Systematic Review of Treatment Options, Outcomes, and Return to Sport
Authors: Sandoval Luke A. , Reiter Charles R. , Satalich James R. , O'Neill Conor N. , Cyrus John W. , Vap Alexander R. 
Published: February 2024

Introduction Partial patellar tendon tears (PPTTs) are overuse injuries in sports with frequent jumping, such as basketball and volleyball. There are several treatment options, including both operative and non-operative modalities. Current literature is largely focused broadly on patellar tendinopathy; however, there are few studies which specifically evaluate treatment outcomes for PPTTs. Objective To systematically review the literature on treatment options, clinical outcomes, and return to sport (RTS) in athletes with a PPTT. Methods PubMed, Embase, and Cochrane were searched through May 1st, 2023 for studies reporting treatment outcomes in athletes with partial patellar tendon tears. Data was extracted on the following topics: treatment modalities, surgical failures/reoperations, surgical complications, RTS, and postoperative time to RTS. Results The review covers 11 studies with 454 athletes: 343 males (86.2%) and 55 females (13.8%). The average age was 25.8 years, ranging from 15 to 55 years. 169 patients (37.2%) received only non-operative treatments, while 295 (65.0%) underwent surgery. 267 patients (92.1%) returned to sports after 3.9 months of treatment. The average follow-up was 55.8 months. Conclusion Our review of current literature on PPTTs in athletes illustrates over 90% return to sport following either conservative or surgical treatment. There is currently little data that directly compares the treatment options to establish an evidence-based “gold-standard” treatment plan. The data we present suggests that current treatment options are satisfactory but would benefit from future study.
Factors Influencing Patient Satisfaction with Total Joint Replacement Surgery
Authors: Ponnamaneni Dhrupad , Mangal Rohan , Gould Murdoc , Stead Thor , Ganti Latha 
Published: February 2024

Background Replacement arthroplasty surgery is a surgical procedure that is needed to restore the activity of a joint. Patient satisfaction regarding arthroplasty surgery is influenced by post-operative complication rate, ability to afford care, and quality of interaction. In this study, we assessed patients’ postoperative complications, mobility, and pain management as proxies for their overall satisfaction with total joint replacement (TJR). Methods An anonymous web-based survey was conducted for patients who had undergone any total joint replacement surgery in the US. Respondents were adults living in the United States. Results 180 individuals met the inclusion criteria and responded to the survey. Age, education, gender, and race were fitted against the patient satisfaction level with the surgeon. While education [P=0.4720], gender [P=0.5097 ], and race [P=0.8183] were not significant, age in years [P=0.02340] was predictive of overall satisfaction levels [R2=0.0213]. When controlling for BMI, infection [P=0.0164], nerve damage [P=0.0250], delayed healing [P=0.0024], hematoma [P=0.0497], were more likely to occur in participants who have had a knee replacement, as compared to shoulder and hip replacement surgery. When controlling for mobility before surgery vs. mobility after surgery [P=0.0114], patients who selected the highest level of mobility before surgery were likely to select the highest level of mobility after surgery. Medicaid, Medicare, private insurance, employer-based insurance, and no insurance were fitted against the patient’s self-reported difficulty in paying for their treatment/care. Although employer-based insurance [P=0.0790] was not significant in predicting difficulty in paying for the surgery, patients with Medicaid [P=0.0280], Medicare [P=0.0200], or private insurance [P=0.0343] did. Conclusion In this cohort, older patients were associated with having improved satisfaction with the surgeon who performed their joint replacement. Complications were higher in patients who underwent a knee arthroplasty compared to a shoulder or hip arthroplasty.