bluuebunny/crossref_metadata_2025_split huggingface dataset:
An innovative EFD using FBG pressure sensors for ship seakeeping
Authors: Suzuki Kantaro , Iwashita Hidetsugu , Kashiwagi Masashi , Wakahara Masahito , Iida Takahito , Minoura Munehiko 
Published: February 2024

AbstractThis paper examines the acquisition of the measurement data of the spatial distribution of unsteady pressure on a ship advancing in waves. The purpose of the study is to investigate the reliability of the pressure data obtained by the unprecedented experiment and to provide experimental data of unsteady pressure which can be used for validation of arbitrary computation methods. The optical fiber sensing technology, so-called FBG (fiber Bragg gratings) sensing, is employed as the pressure sensors. In the experiment, 379 FBG pressure sensors (version 7; the latest version) in total are attached to the port side surface of ship model and also ordinary strain-type pressure sensors are embedded in the starboard side for validating reliability of FBG pressure sensors by comparing both results. In addition to the pressure distribution, measurement is made for unsteady hydrodynamic forces such as added mass, damping coefficients, and wave exciting forces, and also for ship motions and added resistance. Most of the measurement is repeated at least five times for each condition, and results of measured pressures are evaluated with mean value and standard deviation. Regarding the added resistance, the distribution for estimating added resistance is also extracted from obtained pressure distribution and its pressure contour is illustrated to show visually which hull region affects the added resistance significantly. Validation of the measured pressure with FBG pressure sensors is carried out also by integrating measured pressures over the ship model surface and comparing it with forces directly measured with load cells. The measured pressure distribution is compared with typical calculation results with the Rankine panel method in frequency domain to demonstrate usefulness of the spatial pressure data for validating the calculation method. Through these studies, it is confirmed that the measured unsteady pressures with FBG pressure sensors are accurate enough and valuable as the validation data for any calculation method.
A high-resolution view of the heterogeneous aging endothelium
Authors: Dobner Sarah , Tóth Fanni , de Rooij Laura P. M. H. 
Published: February 2024

AbstractVascular endothelial cell (EC) aging has a strong impact on tissue perfusion and overall cardiovascular health. While studies confined to the investigation of aging-associated vascular readouts in one or a few tissues have already drastically expanded our understanding of EC aging, single-cell omics and other high-resolution profiling technologies have started to illuminate the intricate molecular changes underlying endothelial aging across diverse tissues and vascular beds at scale. In this review, we provide an overview of recent insights into the heterogeneous adaptations of the aging vascular endothelium. We address critical questions regarding tissue-specific and universal responses of the endothelium to the aging process, EC turnover dynamics throughout lifespan, and the differential susceptibility of ECs to acquiring aging-associated traits. In doing so, we underscore the transformative potential of single-cell approaches in advancing our comprehension of endothelial aging, essential to foster the development of future innovative therapeutic strategies for aging-associated vascular conditions.
Pharmaceutical retail supply chain responses to the COVID-19 pandemic
Authors: Schleifenheimer Maria , Ivanov Dmitry 
Published: February 2024

AbstractIn the wake of the COVID-19 pandemic, the importance of resilient supply chain and operations management in the pharmaceutical industry has intensified. A particular challenge has been the timely adaptation to rapid fluctuations in the business environment to cope with disruptions and ensure the adequate supply of medical equipment and pharmaceuticals. In this study, we perform a simulation-based analysis of pandemic-triggered impacts on pharmaceutical supply chains in Germany with the aim of examining supply chain response to the COVID-19 pandemic. To accomplish this, we build a digital supply chain model using a hybrid approach that combines case study analysis and discrete-event simulation implemented in anyLogistix. Based on the results, we propose a specific response action plan for the pharmaceutical industry that can be deployed in response to severe disruptions and pandemic-like crises. We also offer a resilience framework for the post-pandemic environment as a guideline for strategic decision-making.
Evidentiary Convincing and Evidentiary Fallacies
Authors: Popa Eugen Octav , Cârlan Alexandru I. 
Published: February 2024

AbstractA convincing argument can change a discussant’s commitment regarding the acceptability of a claim, but the same effect can be achieved by examining evidence. Observing objects or events that count as evidence for or against the acceptability of a statement can change one’s commitment regarding that statement. If we speak of fallacies in the realm of convincing through argumentation, can we speak of fallacies in the realm of convincing through evidence? In this paper, we defend an affirmative answer. We introduce and discuss the conceptual implications of evidentiary fallacies as fallacies committed when evidence is fabricated or suppressed during an attempt to resolve disagreement using proof. We then apply the notion of evidentiary fallacy to two real-life examples of mis-executed evidentiary procedures. We conclude that the notion of evidentiary fallacy can contribute to a more comprehensive fallacy theory and can foster new and broadly applicable critical skills.
A Dress Is Not a Yes: Towards an Indirect Mouse-Tracking Measure of Men’s Overreliance on Global Cues in the Context of Sexual Flirting
Authors: Landwehr Ingo , Mundloch Katrin , Schmidt Alexander F. 
Published: February 2024

AbstractAssessing another person’s intention to flirt and, relatedly, their sexual interest is based on the interpretation and weighting of global (e.g., clothing style) and specific (e.g., facial expression) cues. Since cue incongruency increases the risk of erroneous judgments and thus can entail undesirable outcomes for both parties involved, detection of an individual propensity for overly relying on global (sexual) rather than specific (affective) cues is of social and clinical-forensic importance. Using a purpose-designed and pre-validated stimulus set, we developed a mouse-tracking task as an indirect behavioral measure for males’ overreliance on global cues (OGC) in the context of sexual flirting. In a convenience sample of heterosexual cisgender men (N = 79), experimentally induced sexual arousal was shown to increase the probability of OGC as a function of task difficulty (i.e., congruent or incongruent combinations of global and specific cues displayed by a potential female flirting partner). While error rate and reaction time proved to be indicators of OGC, the spatial measures maximum deviation and area under the curve provided less consistent results. In addition, error rate suggested sex drive and sexual objectification to act as moderators of the relationship between sexual arousal and OGC. Exploratory analysis further revealed a theoretically meaningful pattern of correlations between mouse-tracking measures and self-report measures of problematic (e.g., disinhibited, exploitative) sexuality. Implications of the results are discussed and a framework for differentiating potential causes of OGC (i.e., misperception, lack of self-control, and egocentric hedonism) is proposed.
Plant distribution and conservation in mediterranean islands’ lentic wetlands: there is more than aquatic species
Authors: Fois Mauro , Cuena-Lombraña Alba , Artufel Mathieu , Attard Vincent , Cambria Salvatore , Farrugia Krista , Marignani Michela , Minissale Pietro , Pace Andrea , Sciandrello Saverio , Tankovic Eva , Bacchetta Gianluigi 
Published: February 2024

AbstractThis study investigates the distribution and conservation status of plant species in lentic wetlands of Mediterranean islands. Field data on vascular macrophytes were collected from the online national databases of the “Conservation of the island wetlands of the Mediterranean Basin” (MedIsWet). A comprehensive inventory of wetlands was conducted, and information on the main anthropogenic impacts and conservation priorities was compiled. In addition to all vascular hygro- and hydrophytes, we retained information on those species typically adapted to environments with intermittent or temporary wetness. A significant knowledge gap regarding the distribution and conservation of plant species in Mediterranean wetlands was found. A lower endemism rate was observed particularly in coastal wetlands. However, approximately 25% of species, mainly with relatively wide distribution, were identified as endangered or with unknown conservation status. Including all macrophytes adapted to seasonal wetness is crucial when considering wetland conservation efforts. The research emphasised the importance of considering diverse wetland types, including seasonal and permanent, natural and artificial, for effective plant conservation. Artificial wetlands emerged as potential habitats with considerable biodiversity conservation value. This study provides a comprehensive inventory of wetlands and valuable insights into the distribution, ecology, and conservation relevance of aquatic macrophytes in Mediterranean islands. The research enhances our understanding of biogeographic patterns and processes, offers critical information for the management and conservation of Mediterranean island wetlands, and presents a replicable approach that can be applied to other wetland contexts.
Adaptation of fen peatlands to climate change: rewetting and management shift can reduce greenhouse gas emissions and offset climate warming effects
Authors: Bockermann Carla , Eickenscheidt Tim , Drösler Matthias 
Published: February 2024

AbstractIn Germany, emissions from drained organic soils contributed approximately 53.7 Mio. t of carbon dioxide equivalents (CO2-eq) to the total national greenhouse gas (GHG) emissions in 2021. In addition to restoration measures, shifting management practices, rewetting, or using peatlands for paludiculture is expected to significantly reduce GHG emissions. The effects of climate change on these mitigation measures remains to be tested. In a 2017 experimental field study on agriculturally used grassland on organic soil, we assessed the effects of rewetting and of predicted climate warming on intensive grassland and on extensively managed sedge grassland (transplanted Carex acutiformis monoliths). The testing conditions of the two grassland types included drained versus rewetted conditions (annual mean water table of − 0.13 m below soil surface), ambient versus warming conditions (annual mean air temperature increase of + 0.8 to 1.3 °C; use of open top chambers), and the combination of rewetting and warming. We measured net ecosystem exchange of CO2, methane and nitrous oxide using the closed dynamic and static chamber method. Here, we report the results on the initial year of GHG measurements after transplanting adult Carex soil monoliths, including the controlled increase in water level and temperature. We observed higher N2O emissions than anticipated in all treatments. This was especially unexpected for the rewetted intensive grasslands and the Carex treatments, but largely attributable to the onset of rewetting coinciding with freeze–thaw cycles. However, this does not affect the overall outcomes on mitigation and adaptation trends. We found that warmer conditions increased total GHG emissions of the drained intensive grassland system from 48.4 to 66.9 t CO2-eq ha−1 year−1. The shift in grassland management towards Carex paludiculture resulted in the largest GHG reduction, producing a net cooling effect with an uptake of 11.1 t CO2-eq ha−1 year−1. Surprisingly, we found that this strong sink could be maintained under the simulated warming conditions ensuing an emission reduction potential of − 80 t CO2-eq ha−1 year−1. We emphasize that the results reflect a single initial measurement year and do not imply the permanence of the observed GHG sink function over time. Our findings affirm that rewetted peatlands with adapted plant species could sustain GHG mitigation and potentially promote ecosystem resilience, even under climate warming. In a warmer world, adaptation measures for organic soils should therefore include a change in management towards paludiculture. Multi-year studies are needed to support the findings of our one-year experiment. In general, the timing of rewetting should be considered carefully in mitigation measures.
Engaging children in developing algorithmic thinking and debugging skills in primary schools: A mixed-methods multiple case study
Authors: Wong Gary K. W. , Jian Shan , Cheung Ho-Yin 
Published: February 2024

AbstractThis study examined the developmental process of children’s computational thinking using block-based programming tools, specifically algorithmic thinking and debugging skills. With this aim, a group of children (N = 191) from two primary schools were studied for two years beginning from the fourth grade, as they engaged in our block-based programming curriculum in their primary schools. A mixed-methods multiple case study was designed with pre- and posttests, classroom observations and postintervention interviews. The statistical results showed that students’ algorithmic thinking and debugging skills significantly increased through our intervention, with girls gaining more on algorithmic thinking. During the students’ learning process, we found that they demonstrated behavioral, affective, and cognitive engagement while acquiring these skills in schools. This study presents the key to student engagement contributing to the process of computational thinking development, with implications for the design of future computational learning in primary school.
Subject dependent speech verification approach for assistive special education
Authors: Zeki Umut , Karanfiller Tolgay , Yurtkan Kamil 
Published: February 2024

AbstractThe developmental, characteristics and educational competencies of students who need special education are developing slowly in compared to their agemates. This is because their expressive language is different. In order to overcome these challenges, assistive technologies can be used under the supervision of the teachers. In this paper, a person dependent speech verification approach is proposed for special education students. The system verifies the speech of special education students in various ways. Convolutional Neural Network (CNN) is employed for the classification task. Audio signals that are collected as datasets are accomplished by collecting samples from the real education centers involving special education students. For each subject, a different CNN is trained. Obtained audio signals undergo a frequency domain transform, and then their spectrograms are computed. The spectrogram images of every audio sample are then processed as inputs to the CNN. In this way, better representations of the audio signals are achieved where the spectrogram images of the audio files of different subjects are discriminable. This is also the result of special education students’ personal and unique speaking styles. The proposed approach is tested on the dataset that is constructed by real subject recordings. The system achieves promising results by performing comparable recognition accuracies of around 96%.
Effect of seawater temperature and pH on the sperm motility of the European eel
Authors: Sanchez Malbelys P. , França Thales S. , González-López Wendy A. , Morini Marina , Asturiano Juan F. , Pérez Luz 
Published: February 2024

AbstractThe current climate change situation could bring critical effects for marine species, especially those already considered endangered. Although some species can adapt fast to the environmental changes, it is necessary to get into the worst scenario and develop tools to anticipatedly assess the physiological effects of such environmental change. With this purpose, our study aims to determine the effect of a range of seawater temperatures and pHs on sperm motility in the European eel (Anguilla anguilla). Low seawater pH (6.5–7.4) decreased the eel sperm motility in comparison to the control (pH = 8.2). We also studied the combined effect of the pH of the artificial seminal plasma (the plasma where the sperm cells are suspended) with the pH of Artificial Sea Water (ASW, pH 7.8 or and 8.2). We did not find statistical differences in sperm motility and kinetic parameters caused by the artificial seminal plasma pH. However, seawater pH induced significantly higher values of total sperm motility, and the percentage of fast spermatozoa with a pH of 8.2 in comparison with a pH of 7.8. In contrast, the seawater temperature did not affect sperm motility parameters or sperm longevity. To study the effect of the interaction between seawater temperature and pH on sperm motility, two temperatures: 4 and 24 °C, and two pHs 7.8 and 8.2, were tested. There were significant differences between temperature and pH in several kinetic parameters and, in general, the lowest values were observed in the samples activated at low temperature and low pH (4 °C, pH 7.8). This work suggest that eel sperm motility and kinetics will not be affected by the expected changes in pH or temperature due to the climate change.
Topological and dynamical properties of Torelli groups of partitioned surfaces
Authors: Baik Hyungryul , Shin Hyunshik , Tranchida Philippe 
Published: February 2024

AbstractPutman introduced a notion of a partitioned surface which is a surface with boundary with decoration restricting how the surface can be embedded into larger surfaces, and defined the Torelli group of the partitioned surfaces. In this paper, we study some topological and dynamical aspects of the Torelli groups of partitioned surfaces. More precisely, first we obtain upper and lower bounds on the cohomological dimension of Torelli groups of partitioned surfaces and show that those two bounds coincide when at most three boundary components are grouped together in the partition of the boundary. Second, we study the asymptotic translation lengths of Torelli groups of partitioned surfaces on the corresponding curve complexes. We show that the minimal asymptotic translation length asymptotically behaves almost like the reciprocal of the Euler characteristic of the surface. This generalizes the previous result of the first and second authors on Torelli groups for closed surfaces.
Long-term clinical outcomes of patients with sympathetic ophthalmia
Authors: Mavris Neofytos , Amer Radgonde 
Published: February 2024

Abstract
Purpose
To present the long-term clinical outcomes of patients with sympathetic ophthalmia (SO).

Methods
Retrospective review of patients’ medical files between 2002 and 2022.

Results
Included were seven patients (four males). The mean ± SD age at presentation was 37.9 ± 22.5 years. Four patients had co-morbidities: three had diabetes mellitus type 2 and one had Turner Syndrome. Trauma was the inciting event in six patients and postoperative endophthalmitis in one patient. Decreased visual acuity (VA) was the leading symptom in the sympathizing eye and all of the patients presented with panuveitis. The mean ± SD interval between the triggering incident and the onset of SO in six cases was 4.3 ± 4.2 months. One case presented 30 years following the eye injury. Five patients underwent enucleation/evisceration of the exciting eye. The mean ± SD presenting LogMAR BCVA in the sympathizing eye was 0.57 ± 0.82, and the final LogMAR BCVA was 0.61 ± 0.95. Inflammation was completely controlled in 5 patients at a mean ± SD of 8.55 ± 9.21 months following the institution of immunomodulatory therapy, and it was partially controlled in 2 patients. VA deteriorated in all 3 diabetic patients and improved or remained stable in the 4 young and healthy patients. The mean ± SD follow-up period after achieving drug-free remission was 28 ± 22.8 months. The mean ± SD follow-up time was 6.8 ± 5.6 years.

Conclusions
SO is one of the most sight-threatening conditions, affecting the healthy eye. In this cohort, the favorable visual outcome was especially seen in young and healthy individuals. Visual prognosis is directly related to prompt diagnosis and treatment.
Interface Gain-of-Function Mutations in TLR7 Cause Systemic and Neuro-inflammatory Disease
Authors: David Clémence , Badonyi Mihaly , Kechiche Robin , Insalaco Antonella , Zecca Marco , De Benedetti Fabrizio , Orcesi Simona , Chiapparini Luisa , Comoli Patrizia , Federici Silvia , Gattorno Marco , Ginevrino Monia , Giorgio Elisa , Matteo Valentina , Moran-Alvarez Patricia , Politano Davide , Prencipe Giusi , Sirchia Fabio , Volpi Stefano , Masson Cécile , Rice Gillian I. , Frémond Marie-Louise , Lepelley Alice , Marsh Joseph A. , Crow Yanick J. 
Published: February 2024

AbstractTLR7 recognizes pathogen-derived single-stranded RNA (ssRNA), a function integral to the innate immune response to viral infection. Notably, TLR7 can also recognize self-derived ssRNA, with gain-of-function mutations in human TLR7 recently identified to cause both early-onset systemic lupus erythematosus (SLE) and neuromyelitis optica. Here, we describe two novel mutations in TLR7, F507S and L528I. While the L528I substitution arose de novo, the F507S mutation was present in three individuals from the same family, including a severely affected male, notably given that the TLR7 gene is situated on the X chromosome and that all other cases so far described have been female. The observation of mutations at residues 507 and 528 of TLR7 indicates the importance of the TLR7 dimerization interface in maintaining immune homeostasis, where we predict that altered homo-dimerization enhances TLR7 signaling. Finally, while mutations in TLR7 can result in SLE-like disease, our data suggest a broader phenotypic spectrum associated with TLR7 gain-of-function, including significant neurological involvement.