bluuebunny/crossref_metadata_2025_split huggingface dataset:
Role of Metasomatism in the Development of the East African Rift at the Northern Tanzanian Divergence: Insights From 3D Magnetotelluric Modeling
Authors: Özaydın Sinan , Selway Kate , Foley Stephen F. , Ezad Isra S. , Griffin William L. , Tarits Pascal S. , Hautot Sophie 
Published: January 2024

AbstractThe Northern Tanzanian Divergence in the East Africa Rift is arguably the best place on Earth to study the controls on rifting of thick lithosphere. Here, where the East Africa Rift intersects the Tanzanian Craton and the Mozambique Belt, the relationships between volcanism, faulting, pre‐existing structures and lithospheric thickness and composition can be observed. In this work, we carry out the first lithospheric‐scale 3D magnetotelluric modeling of the Northern Tanzanian Divergence and combine the results with experimental electrical conductivity and petrology models to calculate mantle composition, which is also inferred in the craton from reanalysis of garnet xenocryst data. Our results show that metasomatic materials exist in the cratonic lithospheric mantle and the relatively undeveloped southern part of the rift zone. However, the lithospheric mantle of the Mozambique Belt and the more developed northern section of the rift is more resistive and does not contain metasomatic phases. Combined with geochemical data from erupted lavas, these results suggest that, in zones that have experienced voluminous Cenozoic magmatism, melting events have destroyed the metasomes and dehydrated the mantle. Since the presence of magma is a primary control of lithospheric strength, rifting may become limited as the lithospheric mantle becomes dehydrated and harder to melt.
LncRNA HOTAIR regulates autophagy and proliferation mechanisms in premature ovarian insufficiency through the miR-148b-3p/ATG14 axis
Authors: Luo Chao , Wei Lun , Qian Fei , Bo Le , Gao Shasha , Yang Guangzhao , Mao Caiping 
Published: January 2024

AbstractPremature ovarian insufficiency (POI) is a serious disease significantly affecting the physical and mental health of women of reproductive age, not just impacting fertility outcomes. Ovarian damage due to chemotherapy remains a major cause of this condition. Recent studies have indicated the involvement of the long non-coding RNA HOTAIR in the progression of various diseases, showcasing important biological functions, yet its role in POI remains unclear. We conducted microarray dataset analysis and qRT-PCR experiments, demonstrating downregulation of HOTAIR expression in ovarian tissue and granulosa cells. Various functional experiments using plasmids overexpressing HOTAIR confirmed its promotion of cisplatin-induced granulosa cell autophagy and proliferation. Mechanistically, dual-luciferase assays showed that HOTAIR modulates ATG14 levels in POI by binding miR-148b-3p, thereby enhancing levels of autophagy and proliferation. In this study, we first explored the impact of miR-148b-3p on POI and found that overexpression of miR-148b-3p reversed the promotion of autophagy and proliferation induced by HOTAIR overexpression. The inhibitory effect of miR-148b-3p inhibitor on KGN cell autophagy and proliferation improvement could also be reversed by silencing ATG14. Overall, our findings indicate the promoting role of HOTAIR in POI and its potential as a biomarker for POI by modulating the miR-148b-3p/ATG14 axis to improve mechanisms of autophagy and proliferation in POI.
Characteristics of the steam degradation of poly(lactic acid) and poly(3-hydroxybutyrate-co-3-hydroxyhexanoate)
Authors: Shao Zhuze , Kumagai Shogo , Saito Yuko , Yoshioka Toshiaki 
Published: January 2024

AbstractThe introduction of biodegradable plastics is considered a practical approach to reducing plastic waste accumulation in the environment. Regardless of their biodegradability, plastics should be recycled to effectively utilize and circulate carbon as a resource. Herein, the use of pyrolysis was examined as a method for recycling two common biobased/biodegradable plastics: PLA and PHBH. The pyrolysis of PLA produced lactides (10.7 wt% at 400 °C), but the yield was decreased when the pyrolysis temperature was increased. The presence of steam promoted the hydrolysis of PLA: a steam concentration of 25 vol % increased, the production of lactides at 400 °C to 17.4 wt%. The pyrolysis of PHBH primarily yielded crotonic acid (30.1 wt% at 400 °C), and the yield increased with increasing pyrolysis temperature (71.8 wt% at 800 °C). Steam injection increased the hydrolysis of oligomers, resulting in a 76.1 wt% yield of crotonic acid at 600 °C with a steam concentration of 25 vol %. Thus, we determined that hydrolysis and pyrolysis progress simultaneously under a steam atmosphere, increasing the chemical feedstock recovery from PLA and PHBH. These findings may lead to the proposal of effective degradation methods for treating biobased/biodegradable plastic wastes and ways to maximize the conversion efficiency and target product yields.
Unravelling the mechanisms of underweight in Parkinson’s disease by investigating into the role of gut microbiome
Authors: Shih Ling-Chieh , Lin Ru-Jen , Chen Yan-Lin , Fu Shih-Chen 
Published: January 2024

AbstractApproximately half of patients with Parkinson’s disease (PD) suffer from unintentional weight loss and are underweight, complicating the clinical course of PD patients. Gut microbiota alteration has been proven to be associated with PD, and recent studies have shown that gut microbiota could lead to muscle wasting, implying a possible role of gut microbiota in underweight PD. In this study, we aimed to (1) investigate the mechanism underlying underweight in PD patients with respect to gut microbiota and (2) estimate the extent to which gut microbiota may mediate PD-related underweight through mediation analysis. The data were adapted from Hill‐Burns et al., in which 330 participants (199 PD, 131 controls) were enrolled in the study. Fecal samples were collected from participants for microbiome analysis. 16S rRNA gene sequence data were processed using DADA2. Mediation analysis was performed to quantify the effect of intestinal microbial alteration on the causal effect of PD on underweight and to identify the key bacteria that significantly mediated PD-related underweight. The results showed that the PD group had significantly more underweight patients (body mass index (BMI) < 18.5) after controlling for age and sex. Ten genera and four species were significantly different in relative abundance between the underweight and non-underweight individuals in the PD group. Mediation analysis showed that 42.29% and 37.91% of the effect of PD on underweight was mediated through intestinal microbial alterations at the genus and species levels, respectively. Five genera (Agathobacter, Eisenbergiella, Fusicatenibacter, Roseburia, Ruminococcaceae_UCG_013) showed significant mediation effects. In conclusion, we found that up to 42.29% of underweight PD cases are mediated by gut microbiota, with increased pro-inflammatory bacteria and decreased SCFA-producing bacteria, which indicates that the pro-inflammatory state, disturbance of metabolism, and interference of appetite regulation may be involved in the mechanism of underweight PD.
A data set of symptoms and needs of individuals affected by COVID-19
Authors: Stanley H. B. , Bensafi M. 
Published: January 2024

AbstractHere we provide data from an online survey of 639 people diagnosed with COVID-19 and resident in France, who were diagnosed with COVID-19 between 30th Jan 2020 and 29th August 2022. In addition to demographic information the survey includes questions about participants’ symptoms (by category), symptom onset and persistence, and the effects these symptoms had on their daily lives. Participants were able to include information related to their perceived medical, social and professional needs. These data are needed in order to create effective care policies addressing post-COVID sequelae. Information related to symptom association & dynamics is expected to be useful to clinicians and may also inform more fundamental studies.
Humid and cold forest connections in South America between the eastern Andes and the southern Atlantic coast during the LGM
Authors: Pinaya Jorge Luiz Diaz , Pitman Nigel C. A. , Cruz Francisco William , Akabane Thomas K. , Lopez Maria del Carmen Sanz , Pereira-Filho Augusto José , Grohman Carlos H. , Reis Luiza Santos , Rodrigues Erika S. Ferreira , Ceccantini Gregório C. T. , De Oliveira Paulo Eduardo 
Published: January 2024

AbstractThe presence of Andean plant genera in moist forests of the Brazilian Atlantic Coast has been historically hypothesized as the result of cross-continental migrations starting at the eastern Andean flanks. Here we test hypotheses of former connections between the Atlantic and Andean forests by examining distribution patterns of selected cool and moist-adapted plant arboreal taxa present in 54 South American pollen records of the Last Glacial Maximum (LGM), ca. 19–23 cal ka, known to occur in both plant domains. Pollen taxa studied include Araucaria, Drimys, Hedyosmum, Ilex, Myrsine, Podocarpus, Symplocos, Weinmannia, Myrtaceae, Ericaceae and Arecaceae. Past connectivity patterns between these two neotropical regions as well as individual ecological niches during the LGM were explored by cluster analysis of fossil assemblages and modern plant distributions. Additionally, we examined the ecological niche of 137 plant species with shared distributions between the Andes and coastal Brazil. Our results revealed five complex connectivity patterns for South American vegetation linking Andean, Amazonian and Atlantic Forests and one disjunction distribution in southern Chile. This study also provides a better understanding of vegetation cover on the large and shallow South American continental shelf that was exposed due to a global sea level drop.
Solution of convection-diffusion model in groundwater pollution
Authors: Rashidinia Jalil , Momeni Arefeh , Molavi-Arabshahi Mahboubeh 
Published: January 2024

AbstractThis research involves the development of the spectral collocation method based on orthogonalized Bernoulli polynomials to the solution of time-fractional convection-diffusion problems arising from groundwater pollution. The main aim is to develop the operational matrices for the fractional derivative and classical derivatives. The advantage of our approach is to orthogonalize the Bernoulli polynomials for the sake of creating sparse operational matrices in such a way that classical derivatives have one sub-diagonal non-zero entries only, and also creating an operational matrix for fractional derivative have diagonal matrix only. Due to these properties, the cost of computational our approach is very low and the convergence is fast. A discussion on the error analysis for the presented approach is given. Two test problems are considered to illustrate the effectiveness and applicability of our method. The absolute error in the computed solution compares with the existing method in the literature. The comparison shows that our method is more accurate and easily implemented.
Thermogravimetric and thermo-kinetic analysis of sugarcane bagasse pith: a comparative evaluation with other sugarcane residues
Authors: Najafi Hamidreza , Golrokh Sani Ahmad , Sobati Mohammad Amin 
Published: January 2024

AbstractIn this study, thermogravimetric and thermo-kinetic analysis of sugarcane bagasse pith (S.B.P.) were performed using a robust suite of experiments and kinetic analyses, along with a comparative evaluation on the thermo-kinetic characteristics of two other major sugarcane residues, namely sugarcane straw (S.C.S.) and sugarcane bagasse (S.C.B.). The thermogravimetric analysis evaluated the pyrolysis behavior of these residues at different heating rates in a nitrogen atmosphere. The Kissinger, advanced non-linear isoconversional (ANIC), and Friedman methods were employed to obtain effective activation energies. Moreover, the compensation effect theory (CE) and combined kinetic analysis (CKA) were used to determine the pre-exponential factor and pyrolysis kinetic model. Friedman's method findings indicated that the average activation energies of S.C.S., S.C.B., and S.B.P. are 188, 170, and 151 kJ/mol, respectively. The results of the ANIC method under the integral step Δα = 0.01 were closely aligned with those of the Friedman method. The CKA and CE techniques estimated ln(f(α)Aα) with an average relative error below 0.7%. The pre-exponential factors of S.C.S., S.C.B., and S.B.P. were in the order of 1014, 1012, and 1011 (s−1), respectively. From a thermodynamic viewpoint, positive ∆G* and ∆H* results provide evidence for the non-spontaneous and endothermic nature of the pyrolysis process, indicating the occurrence of endergonic reactions.
Introducing graphene quantum dots in decomposable wheat starch-gelatin based nano-biofilms
Authors: Bakeshlouy Afshar Marzieh , Poursattar Marjani Ahmad , Gozali Balkanloo Peyman 
Published: January 2024

AbstractThis research aims to discover a viable substitute for the common harmful plastic packaging utilized in food products. Citric acid was employed as an accessible and risk-free precursor in synthesizing graphene quantum dots (GQDs). Using the efficient carbonization technique, GQDs were obtained and subsequently transferred to nano-biofilms in varying percentages relative to natural polymers. FT-IR, XRD, FE-SEM, EDX, and AFM analyses were conducted to examine the formation of the nano-biofilms. GQDs demonstrated optimal performance in the disk diffusion method and the 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical approach. Adding GQDs to starch and gelatin composite improved the physical properties of nano-biofilms such as moisture contact, swelling index, and solubility. The transparency of the films was reduced by GQDs, which reduces the transmission of visible light and plays an important role in food protection. The packaging films' weight loss due to decomposition was examined after being buried in soil for 50 days, which relieved the eco-concerns of these packaging films. To evaluate the performance of the films in inhibiting food spoilage, cherries, and cucumbers were packed with a control film and the fabricated film containing 14 wt% of GQD. After 14 days, the modified nano-biofilm was able to maintain the freshness of the samples.
Exploring the factors affecting elementary mathematics teachers’ innovative behavior: an integration of social cognitive theory
Authors: Li Kai , Wijaya Tommy Tanu , Chen Xiaoying , Harahap Muhammad Syahril 
Published: January 2024

AbstractTeacher innovative behavior is one of the vital factors, affecting student engagement, addresses diverse needs, promotes critical thinking, fosters lifelong learning, and contributes to educational research and development. By encouraging and supporting teacher innovation, we may can ensure that education remains relevant, effective, and impactful in preparing students for the future. Teacher innovative behavior is also needed to improve the mathematics skills of elementary school students, and it is important to determine the predictors that significantly affecting Teacher innovative behavior. Therefore, this study aimed to develop a model that predicted possible factors affecting mathematics teachers' innovative behavior based on Social Cognitive Theory (SCT). Data were collected from 132 elementary school teachers in China to verify the model, and the analysis was conducted using a structural equation modelling approach. Theoretically, 10 of the 15 hypotheses were found to be significant. The results showed that facilitating conditions and self-efficacy significantly affect mathematics teachers' innovative behavior. Meanwhile, Technological, Pedagogical and Content Knowledge (TPACK) knowledge, Social Influences, Rewards, Work engagement and anxiety did not show any effect. The contribution developed a model and provided new knowledge about the factors affecting elementary school teachers' innovative behavior. Practically, this could be used to improve teachers' innovative behavior.
Single-Center Experience with Therapeutic Hypothermia for Hypoxic–Ischemic Encephalopathy in Infants with <36 Weeks' Gestation
Authors: Moran Patricia , Sullivan Kelsey , Zanelli Santina A. , Burnsed Jennifer 
Published: January 2024

Objective Hypoxic–ischemic encephalopathy (HIE) is a leading cause of morbidity and mortality in neonates. Therapeutic hypothermia (TH) has improved outcomes and mortality in infants with >36 weeks' gestational age (GA) with moderate-to-severe HIE. There are limited data on the safety and efficacy of TH in preterm infants with HIE. This study describes our experience and examines the safety of TH in neonates with <36 weeks' GA.
Study Design A single-center, retrospective study of preterm neonates born at <36 weeks' GA with moderate-to-severe HIE and treated with TH, compared to a cohort of term neonates with HIE (≥37 weeks' GA), was conducted. The term cohort was matched for degree of background abnormality on electroencephalogram, sex, inborn versus outborn status, and birth year. Medical records were reviewed for pregnancy and delivery complications, need for transfusion, sedation and antiseizure medications, electroencephalography and imaging findings, and in-hospital mortality.
Results Forty-two neonates born at <36 weeks' GA with HIE received TH between 2005 and 2022. Data from 42 term neonates were analyzed for comparison. The average GA of the preterm cohort was 34.6 weeks and 39.3 weeks for the term cohort. Apgar scores, degree of acidosis, and need for blood product transfusions were similar between groups. Preterm infants were more likely to require inotropic support (55 vs. 29%, p = 0.026) and hydrocortisone (36 vs. 12%, p = 0.019) for hypotension. The proportion of infants without evidence of injury on magnetic resonance imaging was similar in both groups: 43 versus 50% in preterm and term infants, respectively. No significant difference was found in mortality between groups.
Conclusion In this single-center cohort, TH in preterm infants appears to be as safe as in term infants, with no significant increase in intracranial bleeds or mortality. Preterm infants more frequently required inotropes and steroids for hypotension. Further research is needed to determine efficacy of TH in preterm infants.
Key Points
Multidisciplinary Treatment: Follow-Up of Dental Autotransplantation for 10 Years
Authors: Camargo Elisa Souza , Silva Rhafaela Ribeiro , Rodrigues Ádelin Olívia Lopes Joly , Andreis Patricia Kern Di Scala , Maciel José Vinicius Bolognesi , Luczyszyn Sônia Mara , de Souza Evelise Machado , Carneiro Everdan , Vanzela Nathália Juliana , Carlini João Luiz 
Published: January 2024

AbstractThe objective is to present a clinical case of dental autotransplantation managed with surgery, orthodontics, endodontics, periodontics, and aesthetic rehabilitation. A 10-year-old boy sought treatment after avulsion of the maxillary left central incisor, which was not reimplanted. Based on anamnesis, clinical examination, and complementary examinations, agenesis of the maxillary and mandibular second premolars except the mandibular right second premolar was observed. After a multidisciplinary planning, the space in the maxillary left central incisor region was opened to receive the transplanted mandibular right second premolar. The receptor site was created in a single surgical procedure. Pulp necrosis was noted in the transplanted tooth, which was treated endodontically, and the agenesis spaces were closed using fixed orthodontic appliances. After removing the appliance, gingivectomy with osteotomy was performed in the maxillary right central incisor and the transplanted tooth regions to harmonize the height and shape of the gingival contour. Next, aesthetic readjustment was performed with tooth whitening, using office and home techniques, followed by microabrasion of the vestibular surface of the maxillary right central incisor. Direct composite resin restorations were placed in the maxillary incisors, and the teeth were rehabilitated using incisal and palatal guides. A multidisciplinary approach is essential for reestablishing the function and aesthetics of complex cases involving dental autotransplantation.
Digital transformation, entrepreneurship, and disruptive innovation: evidence of corporate digitalization in China from 2010 to 2021
Authors: Wu Yuan , Li Ziwei 
Published: January 2024

AbstractThe year 2010 was an important turning point for China’s economy, and the digital economy has become its new feature. In the digital economy wave, digital transformation and innovation are two essential starting points for enterprise development. Few studies have examined the effect of companies’ digital transformation on disruptive innovation, neglecting the role of entrepreneurship. This study aims to address this research gap by developing an analytical framework for digital transformation, entrepreneurship, and disruptive innovation. Based on China’s A-listed firms from 2010 to 2021, we use Python to create indicators for digital transformation and examine its impact on disruptive innovation and the role of entrepreneurship using a double fixed-effects model. The results demonstrate that digital transformation significantly promotes disruptive innovation, and entrepreneurship positively moderates this relationship. Furthermore, heterogeneity analyses show that digital transformation’s positive effects of disruptive innovation and entrepreneurship are more pronounced in non-SOEs, companies in growth and decline stages, and nonmanufacturing companies. However, in SOEs and manufacturing firms, entrepreneurship was unable to moderate this relationship. The conclusions reflect the exploration of the realization mechanism and micro-foundations of the current, in-depth digital transformations, and the findings provide reference guidelines for enabling enterprises to realize digital transformation and disruptive innovation and, relevant experiences.
Hybrid magnon-photon system for sensing weak phase
Authors: Han Jia-Yun , Tian Zhao-Peng , Cheng Yu-Di , Huang Hai-Bo , Zhou Xue-Liang , Wu Wen-Huan , Zhou Yuan , Wang Qing-Lan 
Published: January 2024

Abstract
It belongs to a hot topic to sense or detect the weak and even ultra-weak physical quantities by utilizing quantum platforms and methods. We here propose a hybrid magnon-photon system of the yttrium iron garnet (YIG) magnon mode coupled to a microwave cavity, which also includes another degree of freedom with respect to the thermal vibration of this YIG microsphere. In this quasi-tripartite coupling system, we generalize the condition for satisfying energy degeneracy and anti-crossing behaviors. Especially around the zero-energy area, we can get the joint quantum effects of anti-crossing behavior and degeneracy of systemic energy, and then reach a significantly enhanced sensitivity to this phase disturbance. Therefore our proposal can characterize this weak vibration through a phase disturbance and indicate a group of clearly resolvable output spectra. This investigation may be considered as an encouraging attempt on sensing weak quantity by engineering the systemic energy into the critical area for further enlarging its sensitivity to the weak disturbance.