bluuebunny/crossref_metadata_2025_split huggingface dataset:
IMPLEMENTATION OF THE LEAKY PIPE GAME FOR EARLY CHILDHOOD COOPERATION SKILLS
Authors: Andini Yuli Tri 
Published: October 2023

The world of children is a world of play, where children, through playing, it can develop their abilities. Games are part of play and , the implementation of games in kindergarten is often carried out as a means of stimulating children's developmental abilities. The development of cooperative abilities is part of the development of children's social emotional abilities which is important to improve. This is because the ability to collaborate is a provision for being able to mingle with social society in the future. This research aims to determine the implementation of the leaky pipe game to improve the cooperative abilities of young children. This research method is descriptive-qualitative, data collection uses observation, interviews and documentation. The subjects in this research were children aged 5-6 years at An-Nur Glenmore Kindergarten. The results of the research show that the leaky pipe game can be used to improve the cooperative abilities of young children.
Hiệu quả điều trị thống kinh bằng bài thuốc “CTH” tại Bệnh viện Tuệ Tĩnh
Authors: Nguyễn Tôn Quyền , Nguyễn Thị Thủy , Nguyễn Khắc Điền 
Published: October 2023

Đặt vấn đề: Kinh nguyệt là hiện tượng tự nhiên, xuất hiện hàng tháng ở nữ giới. Đau bụng kinh hay còn gọi là Thống kinh, có nhiều mức độ khác nhau, có người bị đau nhẹ, có người đau âm ỉ kéo dài trong vài giờ đến vài ngày, hoặc đau thành từng cơn dữ dội… Đau bụng kinh nếu không được điều trị sớm, có thể ảnh hưởng đến sức khỏe của chị em, đặc biệt là sức khỏe sinh sản, gây hiếm muộn vô sinh ở nữ giới…
Phương pháp nghiên cứu: Nghiên cứu can thiệp lâm sàng so sánh trước và sau điều trị. 45 bệnh nhân được chẩn đoán Thống kinh tại Bệnh viện Tuệ Tĩnh từ năm 2018 đến 2020.
Kết quả: Mức độ đau nhiều (7 – 10 điểm) trước lúc điều trị là 71,1% (32 người), kết quả tỷ lệ giảm đau bụng kinh mức độ nhiều sau 1 kỳ kinh ngừng điều trị là 95,6% (43 người).
Kết luận: Điều trị Thống kinh bằng bài thuốc “CTH” có hiệu quả cao, phương pháp dễ sử dụng; thời gian điều trị ngắn và phù hợp.
Khảo sát kiến thức và thực hành vệ sinh tay thường quy để phòng lây nhiễm covid của sinh viên Trường Cao đẳng Y tế Hà Nội năm 2020
Authors: Lương Anh Vũ , Phạm Văn Tân , Mã Thị Hồng Liên , Vũ Thị Minh Hiền , Hoàng Anh Lân 
Published: October 2023

Hoàn cảnh, lý do nghiên cứu: Dịch bệnh Covid đang gây ra hậu quả vô cùng nghiêm trọng đến kinh tế, chính trị và xã hội tại Việt Nam và toàn thế giới. Trong các biện pháp phòng chống Covid, vệ sinh tay (VST) được coi là một trong những bước quan trọng được nhấn mạnh và triển khai mạnh mẽ tại trường Cao đẳng Y tế Hà Nội.
Phương pháp: Nghiên cứu mô tả cắt ngang tiến cứu trên 749 sinh viên (SV).
Kết quả: 54,3% SV có kiến thức đạt; 45,7% SV có kiến thức chưa đạt. Tỷ lệ SV thực hành vệ sinh tay theo điểm đạt chiếm 50,6%, chưa đạt 49,4%. Có 3 yếu tố liên quan đến kiến thức VST là sinh viên học năm thứ 2 trở lên (OR= 2,18; 95%CI: 1,59-2,96); SV được học VST tại bệnh viện (OR= 3,31; 95%CI: 1,89- 5,81); SV được học cả lý thuyết và thực hành VST tại trường (OR= 2,06; 95%CI: 1,10- 3,84). Có 1 mối liên quan đến thực hành VST là giới nữ (OR= 1.49; 95%CI: (1,02-2,18).
Kết luận: Kiến thức và thực hành về VST của sinh viên chưa tốt. Các yếu tố liên quan đến VST là SV nữ, SV năm thứ 2 trở lên, được học VST tại bệnh viện, được đào tạo cả lý thuyết và thực hành VST.
Kiến nghị: Trường cần tăng cường đào tạo phối hợp cả lý thuyết và kỹ năng VST cho các SV, đặc biệt là các SV nam.
PENGARUH KUALITAS PRODUK DAN BRAND IMAGE TERHADAP KEPUASAN KONSUMEN PADA PRODUK IPHONE DI KOTA BENGKULU
Authors: Sari Selvi Desta , Ilhami Mardhiyah Dwi 
Published: October 2023

This study aims to determine the effect of product quality and brand image on consumer satisfaction (a case study on students of the Faculty of Economics and Business, University of Muhammadiyah Bengkulu). This type of research is called quantitative descriptive research. The subject of this research is the students of the Faculty of Economics and Business, University of Muhammadiyah Bengkulu. The sampling method is accidental sampling. The number of respondents in this study was 150 respondents. The method of data collection is using a questionnaire spreader. The data analysis technique used multiple linear regression analysis and hypothesis testing, namely the t-test and f-test. The results showed that product quality had a positive and significant influence on consumer satisfaction with iPhone products in Bengkulu City. Brand image has a significant effect on consumer satisfaction with iPhone products in Bengkulu City. Partially, the two variables of product quality and brand image have a positive and significant influence on consumer satisfaction.
Hak dan Kewajiban Suami Istri di Masa Pandemi Perspektif UU Perkawinan di Indonesia
Authors: Aisyah Siti 
Published: October 2023

Direktur Jenderal Organisasi Kesehatan Dunia (WHO) Tedros Adhanom Ghebreyesus secara resmi mengumumkan virus Corona (COVID-19) sebagai pandemi, Pandemi terjadi jika suatu penyakit menular tersebar dengan mudah dari manusia ke manusia di berbagai tempat di seluruh dunia. Berangkat dari data tersebut, Keluarga sebagai miniature dunia, rumah tempat pulang, bergantung dan saling menopang antara anggota keluarga yang satu dengan anggota keluarga yang lainnya menjadi tempat yang paling dasar untuk menjadi pijakan bagaimana menyikapi virus corona tersebut, Suami dan Istri sebagai penggerak kehidupan di dalam rumah tangga dipaksa untuk merekonstruksi ulang hak dan kewajiban masing-masing, Prinsip Persamaan (Kesetaraan dan Keadilan) Substantif memastikan bahwa lak-laki dan perempuan memiliki persamaan kedudukan di muka hukum secara de yure dan de facto. Prinsip ini juga memastikan bahwa perempuan dan laki-laki memiliki akses yang sama terhadap sumber daya, memiliki peluang atau kesempatan yang sama, dan menikmati manfaat yang sama dari pembangunan atau kebijakan, Undang-Undang memperkuat apa yang merupakan hal yang sepatutnya menjadi kewajiban suami isteri. Suami yang lalai memberikan hal-hal yang perlu kepada isterinya, itu dapat dipaksakan dengan melalui pengadilan. Isteri yang meninggalkan rumah tanpa alasan-alasan yang sah, maka ia kehilangan hak untuk pemberian nafkah. Jika suami/isteri melalaikan kewajibannya masing-masing dapat mengajukan gugatan ke Pengadilan Agama.
Estimation of Disease Intensity against Cercospora Leaf Spot of Okra (Abelmoschus esculentus L.) Moench through Bio-control Agents with Chemical Fungicides under Prayagraj Condition of India
Authors: Sarangi Debashree , Tiwari Shashi 
Published: October 2023

Okra (Abelmoschus esculentus L.) also known as bhendi is one of the most common vegetable preferred in every household of India. Cercospora leaf spot incited by Cercospora abelmoschi. is one of the emerging disease in Uttar Pradesh Region. An experiment was conducted in Central Research Farm ,SHUATS , Prayagraj in Kharif season of 2022 to evaluate the efficacy of bioagents and chemicals viz., T0 – Untreated control,T1 Mancozeb (1%) + Trichoderma(4%) , T2 - Mancozeb (1%) + Pseudomonas(4%) , T3 Mancozeb (1%) + Bacillus subtilis(4%), T4 - Mancozeb (1%) + Trichoderma (2%) + Pseudomonas(2%) ,T5 - Mancozeb (1%) + Pseudomonas(2%) + Bacillus subtilis(2%), T6 Mancozeb (1%) + Bacillus subtilis(2%) + Trichoderma(2%), T7 - Mancozeb (1%) against Cercospora leaf spot of okra. C. abelmoschi initiates with sooty black, angular spots and cause heavy defoliation Studies revealed that minimum disease intensity was observed in T4 - Mancozeb (1%) + Trichoderma (2%) + Pseudomonas (2%) and is hereby considered as the best treatment out of all the treatments.
Rickettsial Encephalitis: A Case Report
Authors: Gahalot Mohammed Umar , Jacob M. J , Varadarajulu R. 
Published: October 2023

Rickettsia infections, being an important cause of pyrexia of unknown origin, is often misdiagnosed and treated without correct diagnosis because of it’s symptoms mimic other causes and lack of confirmatory tests during initial phase of the illness. They are distributed worldwide with foci of endemicity. They are common in southern Europe. In India the cases of rickettsial infections have been documented mainly from South India. The disease presents with a classic triad of fever, rash and eschar. The clinical spectrum varies from a mild febrile illness to potentially life-threatening complication like meningoencephalitis. Definitive diagnosis of rickettsia infection requires the examination of serum for antibodies during the acute and convalescent phase of illness. Weil-Felix test is a non-specific agglutination test which detects anti rickettsial antibodies in patient’s serum. It is easily available, non-expensive and can be performed rapidly. It can be used to confirm a tentative diagnosis of rickettsial fever during acute phase of the disease. Inspite of its low sensitivity, WF test may be the only serological test available in developing countries like India. The rickettsial organisms are constantly susceptible to tetracyclines, thus making doxycycline,the drug of choice. We are reporting a case of encephalitis in a 20-year-old female who presented to hospital ER with 10 days history of fever, headache and seizures.The patient was brought to the ER with status epilepticus. Status epilepticus treatment protocol was given in the ER, patient intubated and admitted to medical intensive care unit. In ICU, the patient was put on mechanical ventilation. Various blood Investigations including Weil Felix test were done. Treatment started with IV antibiotic, IV acyclovir, IV Levetiracetam and tab Doxycycline 100mg BID through RT. Weil-Felix test came positive for spotted fever group with titres being OX2 1:320, OX19 1:640 and OXK 1:20 . Tab doxycycline was given for 10 days. Patient improved gradually and was extubated on 5th day, and shifted to ward on 10th day. Patient was discharged to home after 2 weeks of hospital stay.
On follow up in neurology OPD, patient had no complaints and with no neurological sequelae. This case report underlines the importance of a high index of clinical suspicion and the benefits of empirical treatment in setting of compatible epidemiological data for rickettsial infections.
The Impact of Distance Online Laughter Yoga (DOLY) on Work Stress, Work Anxiety, Aloneness & Work Depression Feeling on Corporate Employees Who Worked from Home during the COVID Pandemic
Authors: Rawat Harish , Bisht Saloni , Gupta Abhishek , Elahi Irfan , Sachan Anupam Kumar , Vighnahartayyapodu Challa Krishnaveer Abhishek Ram Kukkurah 
Published: October 2023

Aim: This study evaluated the Impact of Distance Online Laughter Yoga (DOLY) on Work Stress, Work Anxiety, aloneness & Work Depression feelings in Corporate Employees Who Worked from Home During the COVID Pandemic
Methods: A pilot randomized controlled trial (RCT) was conducted to assess the effects of distance online laughter yoga (DOLY) on work depression, work anxiety, work stress, and aloneness among adults. Thirty-two participants were randomly assigned to receive DOLY twice weekly for four weeks, while twenty-nine participants were assigned to a control group that received no intervention. Data were collected using the Depression Anxiety Stress Scale (DASS-21) and the De Jong Gierveld Loneliness Scale (DGLS) at the beginning of the study and at week four.
Randomization Process : Using this website (http://www.randomizer.org)
Results: The online laughter yoga (DOLY) intervention resulted in a statistically significant reduction in work depression symptoms (DASS-21: t(59) = -2.31, p < 0.05). The mean work depression scores for the intervention and control groups at pre-test were 10.0 and 12.0, respectively. After the DOLY intervention, the mean work depression scores for the intervention and control groups were 8.0 and 12.0, respectively.
There were no statistically significant differences between the intervention and control groups in work anxiety, work stress, or work loneliness symptoms.
Conclusion: The findings of this study suggest that DOLY may be an effective intervention for reducing work depression symptoms. However, further research is needed to determine whether DOLY is effective in reducing other work-related stressors, such as anxiety, stress, and loneliness.
Elexacaftor–tezacaftor–ivacaftor decreases pseudomonas abundance in the sinonasal microbiome in cystic fibrosis
Authors: Zemke Anna C. , Hilliam Yasmin , Stapleton Amanda L. , Kimple Adam J. , Goralski Jennifer L. , Shaffer Amber D. , Pilewski Joseph M. , Senior Brent A. , Lee Stella E. , Cooper Vaughn S. 
Published: October 2023

AbstractBackgroundChronic rhinosinusitis (CRS) is common in individuals with cystic fibrosis (CF) and is marked by chronic inflammation and episodes of infection that negatively impact quality of life. Several studies have shown that elexacaftor–tezacaftor–ivacaftor (ETI) improves symptoms and examination findings in CF‐CRS. The current study determines the effect of ETI on the sinonasal microbiota in CF.MethodsSinonasal samples were collected under endoscopic visualization before and after starting ETI. Samples were subjected to 16S amplicon sequencing and sequences were processed with the QIIME2 pipeline with subsequent analysis using the vegan R‐package.ResultsTwenty‐nine individual baseline samples and 23 sample pairs pre‐/post‐ETI were available. At baseline, the cohort had samples dominated by Staphylococcus, and alpha diversity was lower than that of a published reference set of individuals without sinonasal disease. Individuals with prior sinus surgery had lower alpha diversity as measured by Shannon Index, Observed Richness, and Faith's phylogenetic diversity Index. Beta diversity differed between individuals with and without allergic rhinitis, with higher Staphylococcus abundance in those with allergic rhinitis. No change in alpha or beta diversity was seen after a median of 9 months on ETI. With ETI, the Pseudomonas genus and the genus containing Burkholderia decreased in samples containing these taxa at baseline. Pseudomonas abundance decreased with treatment as measured by qPCR. Core sinonasal microbiome members Staphylococcus, Corynebacterium, and Streptococcus were unchanged, while Moraxella increased with ETI.ConclusionsTreatment with ETI leads to a reduction in Pseudomonas abundance within the sinonasal microbiome of individuals with Pseudomonas at baseline.
Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease
Authors: Zheng Lukai , Rubinski Anna , Denecke Jannis , Luan Ying , Smith Ruben , Strandberg Olof , Stomrud Erik , Ossenkoppele Rik , Svaldi Diana Otero , Higgins Ixavier Alonzo , Shcherbinin Sergey , Pontecorvo Michael J. , Hansson Oskar , Franzmeier Nicolai , Ewers Michael ,   for the Alzheimer's Disease Neuroimaging Initiative
Published: October 2023

ObjectiveWe aimed to test whether region‐specific factors, including spatial expression patterns of the tau‐encoding gene MAPT and regional levels of amyloid positron emission tomography (PET), enhance connectivity‐based modeling of the spatial variability in tau‐PET deposition in the Alzheimer disease (AD) spectrum.MethodsWe included 685 participants (395 amyloid‐positive participants within AD spectrum and 290 amyloid‐negative controls) with tau‐PET and amyloid‐PET from 3 studies (Alzheimer's Disease Neuroimaging Initiative, 18F‐AV‐1451‐A05, and BioFINDER‐1). Resting‐state functional magnetic resonance imaging was obtained in healthy controls (n = 1,000) from the Human Connectome Project, and MAPT gene expression from the Allen Human Brain Atlas. Based on a brain‐parcellation atlas superimposed onto all modalities, we obtained region of interest (ROI)‐to‐ROI functional connectivity, ROI‐level PET values, and MAPT gene expression. In stepwise regression analyses, we tested connectivity, MAPT gene expression, and amyloid‐PET as predictors of group‐averaged and individual tau‐PET ROI values in amyloid‐positive participants.ResultsConnectivity alone explained 21.8 to 39.2% (range across 3 studies) of the variance in tau‐PET ROI values averaged across amyloid‐positive participants. Stepwise addition of MAPT gene expression and amyloid‐PET increased the proportion of explained variance to 30.2 to 46.0% and 45.0 to 49.9%, respectively. Similarly, for the prediction of patient‐level tau‐PET ROI values, combining all 3 predictors significantly improved the variability explained (mean adjusted R2 range across studies = 0.118–0.148, 0.156–0.196, and 0.251–0.333 for connectivity alone, connectivity plus MAPT expression, and all 3 modalities combined, respectively).InterpretationAcross 3 study samples, combining the functional connectome and molecular properties substantially enhanced the explanatory power compared to single modalities, providing a valuable tool to explain regional susceptibility to tau deposition in AD. ANN NEUROL 2024;95:274–287
Selective Four‐Electron Reduction of Oxygen by a Nonheme Heterobimetallic CuFe Complex
Authors: Zhang Hong‐Tao , Xie Fei , Guo Yu‐Hua , Xiao Yao , Zhang Ming‐Tian 
Published: October 2023

AbstractWe report herein the first nonheme CuFe oxygen reduction catalyst ([CuII(bpbp)(μ‐OAc)2FeIII]2+, CuFe−OAc), which serves as a functional model of cytochrome c oxidase and can catalyze oxygen reduction to water with a turnover frequency of 2.4×103 s−1 and selectivity of 96.0 % in the presence of Et3NH+. This performance significantly outcompetes its homobimetallic analogues (2.7 s−1 of CuCu−OAc with %H2O2 selectivity of 98.9 %, and inactive of FeFe−OAc) under the same conditions. Structure‐activity relationship studies, in combination with density functional theory calculation, show that the CuFe center efficiently mediates O−O bond cleavage via a CuII(μ‐η1 : η2‐O2)FeIII peroxo intermediate in which the peroxo ligand possesses distinctive coordinating and electronic character. Our work sheds light on the nature of Cu/Fe heterobimetallic cooperation in oxygen reduction catalysis and demonstrates the potential of this synergistic effect in the design of nonheme oxygen reduction catalysts.
CO Binding Energy is an Incomplete Descriptor of Cu‐Based Catalysts for the Electrochemical CO2 Reduction Reaction
Authors: Gao Wenqiang , Xu Yifei , Xiong Haocheng , Chang Xiaoxia , Lu Qi , Xu Bingjun 
Published: October 2023

AbstractCO binding energy has been employed as a descriptor in the catalyst design for the electrochemical CO2 reduction reactions (CO2RR). The reliability of the descriptor has yet been experimentally verified due to the lack of suitable methods to determine CO binding energies. In this work, we determined the standard CO adsorption enthalpies (
) of undoped and doped oxide‐derived Cu (OD−Cu) samples, and for the first time established the correlation of
with the Faradaic efficiencies (FE) for C2+ products. A clear volcano shaped dependence of the FE for C2+ products on
is observed on OD−Cu catalysts prepared with the same hydrothermal durations, however, the trend becomes less clear when all catalysts investigated are taken into account. The relative abundance of Cu sites active for the CO2‐to‐CO conversion and the further reduction of CO is identified as another key descriptor.
Uniform Colloidal Polymer Rods by Stabilizer‐Assisted Liquid‐Crystallization‐Driven Self‐Assembly
Authors: Li Minchao , Guo Jin , Zhang Chuang , Che Yanke , Yi Yuanping , Liu Bing 
Published: October 2023

AbstractThe synthesis of anisotropic colloidal building blocks is essential for their self‐assembly into hierarchical materials. Here, a highly efficient stabilizer‐assisted liquid‐crystallization‐driven self‐assembly (SA‐LCDSA) strategy was developed to achieve monodisperse colloidal polymer rods. This strategy does not require the use of block copolymers, but only homopolymers or random copolymers. The resulting rods have tunable size and aspect ratios, as well as well‐defined columnar liquid crystal structures. The integrated triphenylene units enable the rods to exhibit unusual photo‐induced fluorescence enhancement and accompanying irradiation memory effect, which, as demonstrated, are attractive for information encryption/decryption of paper documents. In particular, unwanted document decryption during delivery can be examined by fluorescence kinetics. This SA‐LCDSA‐based approach can be extended to synthesize other functional particles with desired π‐molecular units.
Isolation and Reactivity of Homoleptic Diphosphene Lead Complexes
Authors: Chen Ming , Zhang Zhaoyin , Liu Jun , Li Gongyu , Zhao Lili , Mo Zhenbo 
Published: October 2023

AbstractDue to their limited capacity for π‐backdonation, isolation of π‐complexes of main‐group elements remains a great challenge. We report herein the synthesis of a homoleptic diphosphene lead complex (2) from the degradation of P4 with a bis(germylene)‐stabilized Pb(0) complex. Structural and computational studies showed that 2 possesses significant π bonding interactions between Pb atom and diphosphene ligands, which is reminiscent of transition‐metal diphosphene complexes. Consistent with its unique electronic structure, complex 2 can deliver Pb(0) atoms to perform redox reaction with an iminoquinone to produce a cyclic plumbylene (4) and perform 2,5‐dimethyl‐3,4‐dimethylimidazol‐1‐ylidene (IMe2Me2) induced phosphorus cation abstraction to give an anionic PbP3 complex (6).
Comparisons of coherent systems with two types of heterogeneous components having proportional reversed hazard rates
Authors: Rao T. V. , Naqvi Sameen 
Published: October 2023

AbstractThe comparison of coherent systems in terms of stochastic orders is vital in reliability theory. While there is a considerable amount of literature devoted to comparing systems with homogeneous and independent components, real‐world systems often consist of heterogeneous components. Hence, this article aims to investigate systems with heterogeneous and independent components, as well as, those with heterogeneous and dependent components. For this purpose, we consider systems comprise of three components, which are of two different types of components, namely two components of type A and one component of type B. The system's lifetime distribution is represented using the failure signature when the components are independent, which is a function of the component's life distribution. However, when the components are dependent, the system's lifetime distribution is represented using copula and diagonal sections. Additionally, distorted distributions are utilized to enable distribution‐free stochastic comparisons. Using these representations, we compare systems with components having proportional reversed hazard rates, in three scenarios: (i) when components are heterogeneous and independent; (ii) when components are heterogeneous and dependent; and finally, (iii) comparing systems with homogeneous and independent components with those that have heterogeneous components. To illustrate the applicability of these results, we provide some examples and applications.