bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effects of polysaccharides, organic acids and colloids on the stability of anthocyanin in purple corn
Authors: Pang Wen‐qian , Zhao Han , Li Da‐jing , Li Yue , Liu Chun‐ju , Yu Rui 
Published: December 2023

SummaryPurple corn anthocyanins have rich nutritional value, but anthocyanins have low stability. The main objective of this study was to screen compounds from the common co‐pigments (polysaccharides, organic acids and colloids) that could improve the stability of anthocyanins and to investigate the effect of different co‐pigments on the stability of anthocyanins in purple corn during heat treatment. There were significant differences in copigmentation effects among different types of co‐pigments. The total anthocyanin retention rate of purple corn without co‐pigments was 15.02%. After copigmentation treatment with different compounds, among the polysaccharides, the total anthocyanin retention rates of 15% fructose and 15% glucose were 37.29% and 52.18% respectively. The copigmentation effects of monosaccharides were better than those of disaccharides, sugar alcohols and cyclodextrins. Among the organic acids, the six co‐pigments were all organic acids containing phenolic rings. The retention rates of anthocyanins were 71.47% and 68.21% for 0.06% tannic acid and 0.1% tartaric acid, respectively, indicating high copigmentation effects. The a* value of purple corn was significantly increased after these treatments, indicating that organic acids had stronger copigmentation effects than polysaccharides. In the colloids, the total anthocyanin retention rate of 2.0% pectin was 43.72%, while 0.5% guar gum had a retention rate of 9.82%. However, low concentrations of guar gum promoted the degradation of anthocyanins, indicating weak copigmentation effects for colloids.
Lipid profile in women of different ethnicity with gestational diabetes: Relationship with fetal growth
Authors: Dalfrà Maria Grazia , Burlina Silvia , Ragazzi Eugenio , Pastrolin Silvia , Sartore Giovanni , Lapolla Annunziata 
Published: December 2023

AbstractAims/IntroductionPregnancy complicated by gestational diabetes mellitus (GDM) is characterized by excessive insulin resistance that impairs the metabolism of glucose and lipids. the aim of the study was to examine lipid profiles during pregnancy of women with GDM, and its impact on fetal growth in a multiethnic population.Materials and MethodsThe study included 322 pregnant women of different ethnicity with GDM attending a clinical unit specializing in metabolic diseases.ResultsThe area under the curve for the 75‐g oral glucose tolerance test and glycated hemoglobin were significantly different among all groups. At the time of being diagnosed with GDM, Asian and African mothers had significantly lower levels of total and low‐density liprotein cholesterol than European mothers (P < 0.001). The trend for high‐density liprotein cholesterol was similar. Triglycerides levels in the Asian group (193.6 ± 65.5 mg/dL) were higher than in the African group (133.2 ± 49.6 mg/dL, P < 0.001), whereas the European group presented intermediate values (175.8 ± 58.8 mg/dL), which differed significantly only versus the African group (P < 0.001). Pre‐partum lipid profiles showed a trend quite similar to that observed at diagnosis. The newborn's birthweight was significantly different, with that of African women (3,437 ± 503 g) being the highest, followed by that of European women (3,294 ± 455 g) and of Asian women (3,006 ± 513 g). The rates of macrosomia showed a trend with higher values in the African group (13.5%), followed by the European group (5.7%, P = 0.1162), whereas that of the Asian group was zero (P = 0.0023 vs African).ConclusionsOur data show that lipid profiles in women with GDM differ by ethnicity. The impact of lipid profile on fetal growth is limited and uninfluenced by ethnicity.
Which temperature matters? Effects of origin, rearing and test conditions on the chemical sensitivity of Pardosa amentata
Authors: Duque Tomás , Schäfer Ralf B. , Entling Martin H. 
Published: December 2023

AbstractSpiders may be adversely affected by pesticides, yet they are not included in regulatory risk assessment and a related standard guideline to test their sensitivity to chemicals is lacking. Different laboratory setups, including test temperature and relative humidity, have been shown to influence the sensitivity of spiders. The climate from which spiders originate and the rearing conditions in the laboratory prior to ecotoxicological testing may also alter their sensitivity to chemicals, potentially in interaction with test conditions. We investigated the influence of population origin, rearing and test temperature on the chemical sensitivity of the spider Pardosa amentata towards lambda‐cyhalothrin. We collected female P. amentata carrying egg sacs from two climates, i.e., boreal and cool temperate. Spiders were kept in the laboratory and their offspring were reared and tested at 15, 20 and 25°C. Hatching of egg sacs largely failed at 15°C, while a moderate spiderling mortality (40%) was recorded at 20°C. At 25°C, mortality increased (63%) and a faster developmental rate was observed. Rearing and test temperature had no significant effects on spider chemical sensitivity. However, spider chemical sensitivity differed between populations, with spiders from boreal climate being 38% more sensitive than spiders from cool temperate climate. A higher sensitivity towards lambda‐cyhalothrin increases the risk of population reduction in treated areas, with potential alterations of ecosystem functions such as biological control. Our results suggest that the climatic origin of test organisms deserves stronger attention in ecotoxicological research.
Malaysian joint societies' consensus recommendations on diagnosis and management of disorders of esophagogastric junction outflow
Authors: Chuah Kee Huat , Ramasami Naveen , Mahendran Hans Alexander , Shanmuganathan Ganesananthan , Koleth Glenn George , Voon Kelvin , Gew Lai Teck , Jahit Mohammad Shukri , Lau Peng Choong , Muthukaruppan Raman , Said Rosaida Hj Md , Mahadeva Sanjiv , Ho Shiaw‐Hooi , Lim Shyang Yee , Tee Sze Chee , Siow Sze Li , Ooi Wei Keat , Lee Yeong Yeh 
Published: December 2023

AbstractDisorders of esophagogastric junction (EGJ) outflow, including achalasia and EGJ outflow obstruction, are motility disorders characterized by inadequate relaxation of lower esophageal sphincter with or without impaired esophageal peristalsis. Current guidelines are technical and less practical in the Asia–Pacific region, and there are still massive challenges in timely diagnosis and managing these disorders effectively. Therefore, a Malaysian joint societies' task force has developed a consensus on disorders of EGJ outflow based on the latest evidence, while taking into consideration the practical relevance of local and regional context and resources. Twenty‐one statements were established after a series of meetings and extensive review of literatures. The Delphi method was used in the consensus voting process. This consensus focuses on the definition, diagnostic investigations, the aims of treatment outcome, non‐surgical or surgical treatment options, management of treatment failure or relapse, and the management of complications. This consensus advocates the use of high‐resolution esophageal manometry for diagnosis of disorders of EGJ outflow. Myotomy, via either endoscopy or laparoscopy, is the preferred treatment option, while pneumatic dilatation can serve as a secondary option. Evaluation and management of complications including post‐procedural reflux and cancer surveillance are recommended.
Differential contribution of language and executive functioning to verbal fluency performance in glioma patients
Authors: Collée Ellen , van den Berg Esther , Visch‐Brink Evy , Vincent Arnaud , Dirven Clemens , Satoer Djaina 
Published: December 2023

AbstractGlioma patients often suffer from deficits in language and executive functioning. Performance in verbal fluency (generating words within one minute according to a semantic category–category fluency, or given letter–letter fluency) is typically impaired in this patient group. While both language and executive functioning play a role in verbal fluency, the relative contribution of both domains remains unclear. We aim to retrospectively investigate glioma patients' performance on verbal and nonverbal fluency and to explore the influence of language and executive functioning on verbal fluency. Sixty‐nine adults with gliomas in eloquent areas underwent a neuropsychological test battery (verbal fluency, nonverbal fluency, language, and executive functioning tests) before surgery (T1) and a subgroup of 31 patients also at three (T2) and twelve months (T3) after surgery. Preoperatively, patients were impaired in all verbal fluency tasks and dissociations were found based on tumour location. In contrast, nonverbal fluency was intact. Different language and executive functioning tests predicted performance on category fluency animals and letter fluency, while no significant predictors for category fluency professions were found. The longitudinal results indicated that category fluency professions deteriorated after surgery (T1–T2, T1–T3) and that nonverbal fluency improved after surgery (T1–T3, T2–T3). Verbal fluency performance can provide information on different possible underlying deficits in language and executive functioning in glioma patients, depending on verbal fluency task selection. Efficient task (order) selection can be based on complexity. Category fluency professions can be selected to detect more permanent long‐term deficits.
Clinical significance of rapid detection and diagnosis of Listeria infection in blood with mass spectrometry
Authors: Li Dan , Duan Linyan , Zhang Xiaoyan , Cao Jingrong 
Published: December 2023

AbstractObjectiveListeriosis is caused by the bacterium, Listeria monocytogenes, and is a significant health concern because of high hospitalization and mortality rates. This study reports seven cases of pregnancy‐associated listeriosis diagnosed with matrix‐assisted laser desorption ionization‐time of flight (MALDI‐TOF) mass spectrometry performed on infection‐positive blood culture.MethodsBlood culture‐positive samples of seven patients whose pregnancy was complicated by Listeria infection and treated at Xuanwu Hospital of Capital Medical University between January 2016 and December 2021 were analyzed retrospectively. Strains identified by MALDI‐TOF mass spectrometry were compared with colony identification results. Identification accuracy and consistency were assessed.ResultsA total of seven strains of Listeria were collected from seven pregnant women presented with fever (37.6–39.9°C). Clinical abnormalities included abnormal liver function, emaciation, hypoalbuminemia, hypocalcemia, hypokalemia, hyponatremia, ketosis, mild to moderate anemia, leukopenia, and thrombocytopenia. Compared with the traditional culture method, MALDI‐TOF mass spectrometry led to much earlier identification (4–6 h vs. 3–4 days) with 100% identification accuracy. Of the seven pregnancies complicated by Listeria, only two led to live births. Of the five fetal deaths, three occurred in the second trimester.ConclusionIn this series of pregnancy‐associated listeriosis cases, the fetal mortality rate was 71%. MALDI‐TOF mass spectrometry is a valuable method that can identify Listeria from blood culture rapidly and accurately.
Are orofacial pain and xerostomia associated with differences in diet, sensory perception, appetite and enjoyment of eating?—An explorative study
Authors: Sigurðsson Kristófer , Andersen Barbara Vad , Bendixen Karina Haugaard , Baad‐Hansen Lene 
Published: December 2023

AbstractBackgroundOrofacial function is believed to influence an individual's diet. knowledge on appetite and enjoyment of eating in orofacially impaired individuals is scarce.ObjectiveWe aimed to explore potential associations between impaired orofacial function, that is, orofacial pain, jaw function limitation and xerostomia, respectively, and diet, appetite, taste perception, as well as the enjoyment of eating.MethodsAn online questionnaire was shared among Aarhus University‘s dental patients and through social media. A convenience sample of 351 individuals responded (97 men, 254 women, aged 18–86 years). Participants were divided into groups with and without orofacial pain or xerostomia based on responses. Questions about food intake, appetite, meal‐related well‐being and oral/general health were included. Data were analysed using Mann Whitney U tests, Spearman‘s correlation, Chi‐square tests, and t‐tests.ResultsParticipants with (n = 123) and without (n = 228) orofacial pain differed significantly regarding age, perceived oral/general health, frequency of consumption of for example cooked vegetables and raw whole fruit, perception of sourness, chewiness, and nausea/pain when eating (p ≤ .031).Participants with (n = 101) and without (n = 250) xerostomia differed significantly regarding perceived oral/general health, intake of prepared fruit, alcohol, ice cream/mousse/pudding, general appetite, intake of breakfast and liquid snacks, nausea/pain when eating, taste and chewiness of food (p ≤ .038).ConclusionDiet, appetite, taste and sensory perception, as well as enjoyment of eating of individuals reporting orofacial pain and/or xerostomia differed slightly to that of individuals free of such symptoms. However, due to the explorative nature of this study, the results should be interpreted with caution pending further research on potential long‐term effects on nutritional status and well‐being.
Weak definite nominals
Authors: Aguilar‐Guevara Ana , Oggiani Carolina 
Published: December 2023

AbstractWeak definite nominals are a class of nominals composed of weak definites and bare singulars occurring in the same linguistic environments within and across languages. They display several characteristic properties: restricted distribution, non‐unique reference, sloppy identity in VP‐ellipsis sentences, acceptability in sluicing contexts, narrow‐scope interpretation, lexical constraints, restricted modification, restricted number morphology, meaning enrichment, and discourse referential defectiveness. In this review we explore two main theoretical approaches accounting for the meaning of these expressions, namely, one that treats them as pseudo‐incorporated nominals and another one that attributes to them an abstract object reference. We first discuss the properties of weak definite nominals using Rioplatense Spanish data and then evaluate how both approaches can account for these properties.
To what degree patient‐reported symptoms of central sensitization, kinesiophobia, disability, sleep, and life quality associated with 24‐h heart rate variability and actigraphy measurements?
Authors: Mikkonen Jani , Kupari Saana , Tarvainen Mika , Neblett Randy , Airaksinen Olavi , Luomajoki Hannu , Leinonen Ville 
Published: December 2023

AbstractObjectivesChronic musculoskeletal pain is associated with decreased parasympathetic and increased sympathetic activity in the autonomic nervous system. The objective of this study was to determine the associations between objective measures of heart rate variability (a measure of autonomic nervous system function), actigraphy (a measure of activity and sleep quality), respiration rates, and subjective patient‐reported outcome measures (PROMs) of central sensitization, kinesiophobia, disability, the effect of pain on sleep, and life quality.MethodsThirty‐eight study subjects were divided into two subgroups, including low symptoms of central sensitization (n = 18) and high symptoms of central sensitization (n = 20), based on patient‐reported scores on the Central Sensitization Inventory (CSI). Heart rate variability (HRV) and actigraphy measurements were carried out simultaneously in 24 h measurement during wakefulness and sleep.ResultsA decrease in HRV during the first 2 h of sleep was stronger in the low CSI subgroup compared to the high CSI subgroup. Otherwise, all other HRV and actigraphy parameters and subjective measures of central sensitization, disability, kinesiophobia, the effect of pain on sleep, and quality of life showed only little associations.DiscussionThe high CSI subgroup reported significantly more severe symptoms of disability, kinesiophobia, sleep, and quality of life compared to the low CSI subgroup. However, there were only small and nonsignificant trend in increased sympathetic nervous system activity and poorer sleep quality on the high central sensitization subgroup. Moreover, very little differences in respiratory rates were found between the groups.
Comparison of methods for the detection of porcine cytomegalovirus/roseolovirus in relation to biosafety monitoring of xenotransplantation products
Authors: Denner Joachim , Jhelum Hina , Hansen Sabrina , Kaufer Benedikt B. 
Published: December 2023

AbstractBackgroundThe porcine cytomegalovirus, a porcine roseolovirus (PCMV/PRV), is widely distributed in pig populations. It has been shown that PCMV/PRV was transmitted by pig xenotransplants to non‐human primates, and significantly reduced the survival time of the recipient. PCMV/PRV was also transmitted during the first transplantation of a pig heart into a human patient. PCMV/PRV establishes a lifelong persistent infection (latency) in the host, is difficult to detect in this stage, and consequential poses a threat to future clinical xenotransplantations. Therefore, sensitive and specific methods and goal‐oriented strategies how, when, and where to test should be used for screening donor pigs.MethodsIn this study we compared experimentally the PCMV/PRV detection methods including PCR‐based (real‐time PCR, nested PCR) and immunological methods (Western blot assay, ELISA) recently published by Halecker et al. (Sci. Rep. 2022;12(1):21545) and Fischer et al. (Xenotransplantation 2023:e12803). We also compared the antigens used for antibody detection (a recombinant protein and synthetic peptides corresponding to a conserved region of the glycoprotein B, gB).ResultsThe published methods can be used for screening donor pigs, with the results being similar. The antigens used for the detection of PCMV/PRV‐specific antibodies are almost identical and give comparable results. Overall, the optimal diagnostic tests, the samples used for testing and the time of sampling play a crucial role in preventing the transmission of PCMV/PRV during xenotransplantation.ConclusionSensitive methods are available to screen donor pigs for PCMV/PRV, but a rational application of a combination of PCR‐based and immunological methods as well as rational detection strategies are important for the detection of the virus during latency.
Data Driven Approach to Determine Linear Stability of Delay Differential Equations Using Orthonormal History Functions
Authors: Tiwari Sankalp , Shaik Junaidvali , Vyasarayani C. P. 
Published: December 2023

Abstract
Delay differential equations (DDEs) appear in many applications, and determining their stability is a challenging task that has received considerable attention. Numerous methods for stability determination of a given DDE exist in the literature. However, in practical scenarios it may be beneficial to be able to determine the stability of a delayed system based solely on its response to given inputs, without the need to consider the underlying governing DDE. In this work, we propose such a data-driven method, assuming only three things about the underlying DDE: (i) it is linear, (ii) its coefficients are either constant or time-periodic with a known fundamental period, and (iii) the largest delay is known. Our approach involves giving the first few functions of an orthonormal polynomial basis as input, and measuring/computing the corresponding responses to generate a state transition matrix M, whose largest eigenvalue determines the stability. We demonstrate the correctness, efficacy and convergence of our method by studying four candidate DDEs with differing features. We show that our approach is robust to noise, thereby establishing its suitability for practical applications, wherein measurement errors are unavoidable.
TPIV Experimental Investigation of Film Coolant-to-Mainstream Interaction From Shaped Cooling Holes With Various Inlet Geometries
Authors: Wang Hanlin , Wright Lesley M. 
Published: December 2023

Abstract
In this investigation, multiple sets of time-averaged tomographic particle imaging velocimetry measurements are completed for laid-back, fan-shaped film cooling holes with “racetrack” shaped inlets. Traditional 10-10-10, laid-back, fan-shaped holes are inclined 30 deg to the mainstream flow on a flat plate. The inlet cross section varies from round to two elongated racetrack shapes. The cross-sectional area and the outlet-to-inlet area ratio for all the geometries are held constant. The flat plate is installed in a low-speed wind tunnel with a mainstream turbulence intensity of 8% and an average velocity of 21.6 m/s. The blowing ratios of the film jets range from 0.6 to 1.5 and the density ratio is 1. The Reynolds number of the cooling jet varies from 2600 to 8400. The characteristics of the resulting flowfield are coupled with the detailed film cooling effectiveness distributions. It can be noted from the results that the counter-rotating vortex pair generated by the 2:1 inlet is the closest to the surface and weakest in strength, likely caused by the minimum peak jet momentum of the three. The Reynolds stresses downstream of the 2:1 and 4:1 inlets are significantly lower than those downstream of the shaped hole with a round inlet. An inverse relation between volumetric turbulence accumulation (TA), and surface effectiveness (η), can be correlated for the blowing ratios considered. The turbulence accumulation term can thus be used to evaluate the performance of a film cooling hole design with flowfield data.
Tuning Modal Behavior of Additively Manufactured Lattice Structures
Authors: Beghini Marco , Grossi Tommaso , Macoretta Giuseppe , Monelli Bernardo Disma , Senegaglia Ivan , Turco Paolo del , Fardelli Andrea , Morante Francesco 
Published: December 2023

Abstract
Thanks to the increasingly widespread additive manufacturing technology and promising properties, the use of lattice structures (LS) is becoming increasingly frequent. LS allows the components to be designed with tunable stiffness, which can unlock the control of natural frequencies. However, crucial challenges must be faced to integrate LS into the typical design process. In this work, an experimental and numerical study of LS-enabled tuning of natural frequencies in mechanical components are proposed. In a first step, the difficulties arising with the large amount of finite element method (FEM) nodes, that are required to predict LS complex shapes in detail, are overcome by modeling LS with an elastic metamaterial whose stiffness properties are determined through ad hoc finite element analyses. After that, a simplified investigation can be conducted on the modal properties of components with fixed external shape and variable internal LS filling, based on triply periodic minimal surfaces (TPMS) lattices. In those conditions, the parameters of the LS core can be tuned to control and optimize the global modal frequencies of the entire geometry. In addition, the admissible range of frequencies can be estimated. Optimized plates results are validated through an experimental test campaign on additively manufactured specimens made with laser powder bed fusion technology. The samples are hammer-tested with various boundary conditions while laser sensors measure the oscillation data of selected points. Finally, estimated and identified natural frequencies were compared. The described model is suitable to be implemented in an automated tool for designers.