bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design of health protection technology in the process of beginning physical culture for young students
Authors: Arkhipov O.A. 
Published: November 2023

In the past decades the world science has included the problem of health in its wide interpretation in the circle of global problems, the resolution of which predetermines not only the quantitative and qualitative characteristics of the prospective development of mankind, but also the fact of its further existence as a biological species itself. Nation’s health is regarded as an indicator of the state’s civility reflecting the social and economic condition of the society. According to UNO resolution No. 38/54 of 1997 the population’s health is considered to be the main criterion of the expediency and efficiency of all the spheres of the economic activity without exception. Moreover, the experts believe that about 75% of adults’ diseases result from the living conditions they had in their childhood and youth.
The problem of healthconservation and its purposeful formation in children andyouthhas an exclusive importance and topicalityin the modern conditions of the Ukrainian society development as it is directly connected with the problem of the state existence. In the World Health Declaration (May 1998) the stress is laid upon the fact that the level of state social policy efficiency can be determined by the level of its influence upon the health of the population as a sufficient level of health establishes a solid foundation of a sustainable economic growth.
Analysis of the results of own and medical and social research in recent years shows a significant deterioration in the quality of the student youth. And this trend is sustainable. The issue of the health of children and young people should become a priority not only for medical employees who do not have objective opportunities to fully solve it, but also teachers. It is the latter that are called to form schoolchildren have a conscious attitude to their own health and a healthy lifestyle (HSL) and carry out propaedeutic work in the specified direction.
The main function of out-of-school and out-of-class activity is creation of the most favorable conditions for forming the habit of systematic physical trainings. Classes are only the beginning of all complicated system of this process, which means training during the school day, out-of-class and out-of-school physical and health activity, self-dependent work.
Increasing of effectiveness of the system of physical education at school depends on the correct organization of all the measures. They must be coordinated while planning with the essence of physical culture classes, promote learning of educational material that is predicted with the program. So, all the forms of physical education are united with the common tasks. For optimal solving of all the problems of physical education it is worth practicing different forms of activities by introducing physical-health measures while daily routine, wide pupils’ attraction to training in sport sections and workshops, popularizing of additional and optional classes.
The level of physical fitness in the applicants of higher education
Authors: Riadova Liliana , Korchagin Mikola , Mkrtichian Oksana , Konovalov Volodymyr 
Published: November 2023

The purpose of the study: to determine the level of development of agility, quickness, flexibility, strength, endurance in the applicants of higher education institutions of the I and II courses.
Material and methods of the study. The study was conducted on the basis of the Semen Kuznets Kharkiv National University of Economics and the National Aerospace University «Kharkiv Aviation Institute». It was attended by 849 in the applicants of higher education of the I and II courses aged 17–18 years old.
The applicants of higher education took part in the study voluntarily and were informed about the specifics of the study in advance.
Research methods: theoretical analysis and generalisation of scientific and methodological literature, pedagogical testing, methods of mathematical statistics.
The level of development of agility in the applicants of higher education institutions of the I and II courses was determined by the indicators of «shuttle» running 4×9 m, speed – running for 100 m, flexibility – torso tilt forward from a sitting position, strength – long jump from a place, endurance – uniform running.
Results of the study. The indicators of development of agility, quickness, flexibility, strength and endurance in the applicants of higher education institutions of the I and II courses are considered and compared with the normative data. A comparison of the indicators of these physical qualities in boys and girls in gender and age aspects is presented.
Conclusions. The applicants of higher education institutions of the I and II courses have a low level of physical fitness. The best indicators of agility, quickness and flexibility were found among in the applicants of higher education of the I course; strength and endurance – in the applicants of higher education of the II course.
PENGARUH LEVERAGE, INTENSITAS ASET TETAP, DAN INSENTIF PAJAK TERHADAP AGRESIVITAS PAJAK (Studi Kasus pada Perusahaan Basic Materials di Bursa Efek Indonesia)
Authors: Sulistyoningsih Sulistyoningsih 
Published: November 2023

Berbagai temuan penelitian sebelumnya menjadi pendorong dilakukannya penelitian tentang agresivitas pajak. Selain itu, kebutuhan akan penelitian tambahan berasal dari perbedaan antara perspektif pemerintah dan bisnis. Studi ini bermaksud akan menguji bagaimana agresivitas pajak dipengaruhi oleh leverage, intensitas aset tetap, dan insentif pajak. Seluruh perusahaan Basic Materials yang tercatat dalam Bursa Efek Indonesia yang berjumlah 80 perusahaan menjadi populasi penelitian. Pengamatan dilakukan antara tahun 2019 hingga 2022. Purposive sampling digunakan untuk memilih sampel penelitian, yang menghasilkan total 26 perusahaan dengan 104 data. Laporan keuangan tahunan Bursa Efek Indonesia dapat dilihat di https://www.idx.co.id/id yang menjadi sumber data sekunder untuk studi kasus ini. Model regresi linier berganda dipakai untuk menguji penelitian. Temuan menunjukkan bahwa agresivitas pajak secara positif dan signifikan dipengaruhi oleh intensitas aset tetap dan leverage. Namun, agresivitas pajak tidak terpengaruh oleh insentif pajak.
Kata Kunci: leverage, intensitas aset tetap, insentif pajak, agresivitas pajak
Para além dos DAS
Authors: Palotti Pedro , Masson Pedro 
Published: November 2023

O artigo tem como objetivo caracterizar a disposição e ocupação de funções de confiança e cargos em comissão no governo federal brasileiro. A utilização de funções e cargos em comissão é recorrente nas organizações públicas para assessoramento e estruturação da cadeia de comando dos níveis estratégico e tático com o técnico-operacional. A partir da base de dados do Sistema Integrado de Administração de Pessoal (SIAPE), foram traçadas comparações do quantitativo, do padrão de remuneração e do perfil de ocupação desses postos de comando por tipo de organizações públicas no governo federal. Conclui-se que há muitas similaridades entre funções e cargos, com destaque para elevada escolaridade e o predomínio dos servidores públicos entre os ocupantes. A estratégia de disposição das funções e cargos difere, no entanto, quanto à remuneração e aos níveis de responsabilidade, o que pode resultar em assimetrias e distorções na gestão pública das organizações federais brasileiras.
Dois níveis de legitimidade no humanitarismo da ONU
Authors: Rizzotti Letícia , Fuccille Alexandre 
Published: November 2023

Os 30 anos de humanitarismo multidimensional das Nações Unidas não produziram grandes sistematizações de policy sobre reconstrução política em operações de paz. Esse esforço tampouco consta na literatura que, apesar de ter produzido críticas sobre o modelo do humanitarismo, se debruçou sobre casos específicos ou leituras gerais dos postulados encampados. Este trabalho realiza a sistematização das respostas institucionais, via documentos que revelam os debates internos à Organização: resoluções do Conselho de Segurança e documentos coletados nos Arquivos da ONU em Nova Iorque. Esse conjunto documental revelou uma estratégia de produção de dois níveis de legitimidade para estruturar os instrumentos humanitários: a moralização da proteção e o pragmatismo tecnicista. Conclui-se que este eixo foi caminhou pelo envernizamento tecnocrata, despolitizando as categorias democráticas.
Multiple energy X-ray imaging of metal oxide particles inside gingival tissues
Authors: Cortez Jarrod , Romero Ignacio , Ngo Jason , Azam Md Sayed Tanveer , Niu Chuang , Almeida-da-Silva Cássio Luiz Coutinho , Cabido Leticia Ferreira , Ojcius David M. , Chin Wei-Chun , Wang Ge , Li Changqing 
Published: November 2023

BACKGROUND: Periodontal disease affects over 50% of the global population and is characterized by gingivitis as the initial sign. One dental health issue that may contribute to the development of periodontal disease is foreign body gingivitis (FBG), which can result from exposure to some kinds of foreign metal particles from dental products or food. OBJECTIVE: We design a novel, portable, affordable, multispectral X-ray and fluorescence optical microscopic imaging system dedicated to detecting and differentiating metal oxide particles in dental pathological tissues. A novel denoising algorithm is applied. We verify the feasibility and optimize the performance of the imaging system with numerical simulations. METHODS: The designed imaging system has a focused X-ray tube with tunable energy spectra and thin scintillator coupled with an optical microscope as detector. A simulated soft tissue phantom is embedded with 2-micron thick metal oxide discs as the imaged object. GATE software is used to optimize the systematic parameters such as energy bandwidth and X-ray photon number. We have also applied a novel denoising method, Noise2Sim with a two-layer UNet structure, to improve the simulated image quality. RESULTS: The use of an X-ray source operating with an energy bandwidth of 5 keV, X-ray photon number of 108, and an X-ray detector with a 0.5 micrometer pixel size in a 100 by 100-pixel array allowed for the detection of particles as small as 0.5 micrometer. With the Noise2Sim algorithm, the CNR has improved substantially. A typical example is that the Aluminum (Al) target’s CNR is improved from 6.78 to 9.72 for the case of 108 X-ray photons with the Chromium (Cr) source of 5 keV bandwidth. CONCLUSIONS: Different metal oxide particles were differentiated using Contrast-to-Noise ratio (CNR) by utilizing four different X-ray spectra.
Methodological foundations for the formation of pre-professional IT competencies of high school students in children’s technoparks “Quantorium”
Authors: Sadykova A. R. , Belousova A. S. 
Published: November 2023

Modern state programs for the development of education have set an important task to prepare young people for successful professional self-realization, which implies the involvement of students in programs and activities of early career guidance, support of professional self-determination, and development of professional and socio-cultural competencies.The methods and principles of organizing educational activities of high school students on the basis of the children’s technopark “Quantorium” aim the development of pre-professional IT competencies. Classes in the technopark will make the preparation of students for modern and future IT professions more effective, and will also contribute to their readiness for self-realization and further professional development.Approaches to the development of pre-professional competencies of high school students are based on the project-oriented teaching methodology that promotes the development of teamwork, communication, and project management skills, technological competencies, and creative thinking. The analysis of the modular design principle of additional general educational programs of the technopark is carried out on the example of work in the direction “≪IT-quantum≫”, which is a part of the “Quantorium”. “Quantorium” can become an effective tool to support educational activities aimed at the development of pre-professional competencies in high school students, contributing to the increase of interest in scientific, technical, and IT disciplines.
The American Thyroid Association risk stratification and long-term outcomes of differentiated thyroid cancer: a 20-year follow-up of patients in Saudi Arabia
Authors: Jammah Anwar Ali , AlSadhan Ibrahim Mohammed , Alyusuf Ebtihal Y. , Alajmi Mubarak , Alhamoudi Abdullah , Al-Sofiani Mohammed E. 
Published: November 2023

BackgroundStudies have reported differing factors associated with poor outcomes in patients with differentiated thyroid cancer (DTC). We aimed to describe our 20 years of experience in the management of thyroid cancer (TC) and identify predictors of treatment outcomes.MethodsWe conducted a retrospective review of medical records of patients with TC seen in the Thyroid Center at King Saud University Medical City (KSUMC) in Riyadh, Saudi Arabia, between the years 2000 and 2020. Demographic and clinical data including pathological characteristics were collected. The American Thyroid Association (ATA) risk stratification was determined for all patients at the postoperative period as well as the response to therapy at the final follow-up visit.ResultsA total of 674 patients (mean age: 47.21 years) with TC, 571 (84.7%) of which were women, were included. There were 404 (60.0%) patients with ATA low risk, 127 (18.8%) with intermediate risk, and 143 (21.2%) with high-risk histology. Overall, 461 patients (68.4%) had an excellent response to treatment, 65 (9.6%) had an indeterminate response, 83 (12.3%) had a biochemical incomplete response, and 65 (9.6%) had a structural incomplete response. Patients who had an excellent response were mostly ATA low risk (n = 318 of 431, 68.1%), whereas 40 of 65 patients (61.5%) of those with ATA high-risk histology had a structural incomplete response to treatment. There were significantly more women who had an excellent response compared with men. Obesity, lymphovascular invasion, and size of the tumor were significant predictors of worse outcomes to therapy.ConclusionTumor size, lymphovascular invasion, and obesity are strong predictors of a worse response to therapy among patients with TC. Patients with obesity should be carefully followed up regardless of their risk stratification in light of the recent compelling evidence associating obesity with thyroid cancer and its higher risk of a worse disease outcome. ATA risk stratification is well correlated with patient long-term outcomes.
Risk factors for central lymph node metastasis in patients with papillary thyroid carcinoma: a retrospective study
Authors: Du Jiachen , Yang Qing , Sun Yixuan , Shi Peng , Xu Hao , Chen Xiao , Dong Tianyi , Shi Wenjing , Wang Yatong , Song Zhenzhi , Shang Xingchen , Tian Xingsong 
Published: November 2023

IntroductionThyroid cancer is the most prevalent endocrine malignancy, with its global incidence increasing annually in recent years. Papillary carcinoma is the most common subtype, frequently accompanied by cervical lymph node metastasis early on. Central lymph node metastasis (CLNM) is particularly the common metastasis form in this subtype, and the presence of lymph node metastasis correlates strongly with tumor recurrence. However, effective preoperative assessment methods for CLNM in patients with papillary thyroid carcinoma (PTC) remain lacking.MethodsData from 400 patients diagnosed with PTC between January 1, 2018, and January 1, 2022, at the Shandong Provincial Hospital were retrospectively analyzed. This data included clinicopathological information of the patients, such as thyroid function, BRAF V600E mutation, whether complicated with Hashimoto’s thyroiditis, and the presence of capsular invasion. Univariate and multivariate logistic regression analyses were performed to assess the risk factors associated with cervical CLNM in patients with PTC. Subsequently, a clinical prediction model was constructed, and prognostic risk factors were identified based on univariate and multivariate Cox regression analyses.ResultsUnivariate and multivariate analyses identified that age &gt;45 years (P=0.014), body mass index ≥25 (P=0.008), tumor size ≥1 cm (P=0.001), capsular invasion (P=0.001), and the presence of BRAF V600E mutation (P&lt;0.001) were significantly associated with an increased risk of CLNM. Integrating these factors into the nomogram revealed an area-under-the-curve of 0.791 (95% confidence interval 0.735–0.846) and 0.765 (95% confidence interval: 0.677–0.852) for the training and validation sets, respectively, indicating strong discriminative abilities. Subgroup analysis further confirmed that patients with papillary thyroid microcarcinoma and BRAF V600E mutations who underwent therapeutic central compartment neck dissection had significantly better 3-year disease-free survival than those who had prophylactic central compartment neck dissection (P&lt;0.001).ConclusionThe study revealed that age &gt;45 years, body mass index ≥25, tumor size ≥1 cm, BRAF V600E mutation, and capsular invasion are the related risk factors for CLNM in patients with PTC. For patients with clinically nodal-negative (cN0) papillary thyroid microcarcinoma, accurately identifying the BRAF V600E mutation is essential for guiding the central lymph node dissection approach and subsequent treatments.
Evaluation of effectiveness and safety of the large-format pRESET 6-50 thrombectomy stent-retriever in the endovascular treatment of ischemic stroke: real-world experiences from two tertiary comprehensive stroke centers
Authors: Kraehling Hermann , Akkurt Burak Han , Elsharkawy Mohamed , Schwindt Wolfram , Köhler Michael , Werring Nils , Masthoff Max , Cox Anthony , Minks David , Stracke Christian Paul 
Published: November 2023

ObjectiveMechanical thrombectomy (MT) has become the standard treatment for acute ischemic stroke (AIS) with large vessel occlusion (LVO). First-pass (FP) reperfusion of the occluded vessel and fewer passes with stent retrievers show improvement in functional outcomes in stroke patients, while higher numbers of passes are associated with higher complication rates and worse outcomes. Studies indicate that a larger size of the stent-retriever is associated with a higher rate of first-pass reperfusion and improved clinical outcomes. In this retrospective study, we investigated the clinical performance of a recently developed and one of the largest stent-retrievers available in the treatment of LVO (pRESET 6-50, phenox GmbH, Bochum).Materials and methodsAll consecutive patients with ischemic stroke due to proximal large vessel occlusion treated with MT using the pRESET 6-50 stent-retriever in two tertiary stroke centers between 09/2021 and 07/2022 were included in this study. The reperfusion rate after MT was quantified by the modified thrombolysis in cerebral infarction (mTICI) score, and functional neurological outcome was evaluated with the National Institutes of Health Stroke Scale (NIHSS) score and the major early neurological recovery (mENR) rate after 24 h. Successful FP reperfusion was defined as mTICI ≥ 2b. Successful and complete reperfusion were defined as mTICI ≥ 2b and mTICI ≥ 2c, respectively.ResultsIn total, 98 patients (52 men and 46 women) with a median age of 75 (range 25–95 years) were included. A total of 70 (72%) patients presented with an occlusion of the middle cerebral artery (MCA) in the M1 segment, 6 (6%) patients with an occlusion of the M2 segment, 17 (17%) patients with an occlusion of the internal carotid artery (ICA), and 5 (5%) patients with an occlusion of the obstructed basilar artery (BA). Successful FP reperfusion was achieved in 58 patients (62%). Successful and complete reperfusion were achieved in 95 (97%) and 82 (83%) patients, respectively. The median National Institutes of Health Stroke Scale (NIHSS) in all treated patients improved from 17 to 7.5. Major early neurological recovery (mENR) was observed in 34 patients (35.1%).ConclusionMT with the pRESET 6-50 stent-retriever achieves high successful first-pass and final reperfusion rates in patients with AIS and LVO. The results of this study support the thesis to use large-format stent-retriever in proximal vessel occlusion MT whenever feasible in order to improve high FP and final reperfusion rate, which are known predictors of good clinical outcome.
Long-term follow-up after treatment of tubercular uveitis: case series and review of the literature
Authors: Putera Ikhwanuliman , van Daele Paul L. A. , ten Berge Josianne C. E. M. , Dik Willem A. , La Distia Nora Rina , van Hagen P. Martin , Rombach Saskia M. 
Published: November 2023

IntroductionThere is a scarcity of long-term follow-up data and management strategies for recurrent uveitis in tubercular uveitis (TBU), especially in cases extending beyond 10 years after the completion of initial antitubercular treatment (ATT).MethodsThis retrospective study involved five TBU patients who were initially treated with a combination of four-drug ATT for 6 months, and the five of them had more than 10 years of follow-up after uveitis resolution upon ATT completion. We describe the occurrence of recurrent uveitis and present our approach to managing these recurrent episodes.ResultsRecurrent uveitis and cystoid macular edema (CME) developed in three out of five included TBU patients with a median of 18 years (range 13–20 years) of follow-up. The anatomical sites of the recurrences were anterior, intermediate, and pan-uveitis. The recurrent episodes varied from 6 years to 15 years after ATT completion. Systemic or local corticosteroids/immunosuppressants successfully resolved all recurrent episodes, but one was also treated with the combination of isoniazid monotherapy again. Two patients needed anti-tumor necrosis factor-α therapy.ConclusionLong-term monitoring of TBU patients after ATT completion is warranted. Further well-designed studies with larger sample sizes are required to better estimate the risk of recurrences, investigate the underlying mechanism of recurrences, and identify biomarkers that predict who is at risk for recurrences.
Portuguese translation and validation of the questionnaires from the Canadian Physical Literacy Assessment-2: a pilot study
Authors: Mendoza-Muñoz María , Carlos-Vivas Jorge , Castillo-Paredes Antonio , Parraca Jose A. , Raimundo Armando , Alegrete Joana , Pastor-Cisneros Raquel , Gomez-Galan Rafael 
Published: November 2023

Background/objectivePhysical literacy assessment is considered a vital resource to decrease the prevalence of sedentary lifestyles and physical inactivity in children and adolescents worldwide. In Portugal, there is no physical literacy assessment tool for children under 15 years old. The main objective of this study was to carry out a translation and cultural adaptation of the Canadian Physical Literacy Assessment 2 (CAPL-2) into Portuguese, as well as to test its psychometric properties, in children between 8 and 12 years of age.MethodsThe questionnaires included in the CAPL-2 were translated using the translation-back-translation method and adapted to their context. The test–retest reliability, internal consistency, and confirmatory factor analysis of the CAPL-2 Portuguese version were analyzed in a sample of 69 and 138 students, respectively, from a school in the Alentejo region (Portugal).ResultsThe Portuguese version of the CAPL-2 questionnaires demonstrated high internal consistency (Cronbach’s α: 0.713–0.979) and test–retest reliability ranging from moderate to nearly perfect in the motivation and confidence domain and knowledge and comprehension domain (ICC = 0.549–0.932). The results showed a good fit after adjusting for covariation paths (CMIN/DF = 1.382, p = 0.105, RMSEA = 0.053, CFI = 0.971, TLI = 0.955, NFI = 0.907).ConclusionThe CAPL-2 version of the questionnaires, translated and adapted to the Portuguese context, demonstrated validity and reliability, making them suitable for assessing physical literacy in children aged 8–12 years.