bluuebunny/crossref_metadata_2025_split huggingface dataset:
La Calidad educativa y su relación con la gestión pedagógica, la innovación y los ambientes de aprendizaje
Authors: Fonseca Montoya Somaris , Lolín Cabrera Sugey , Ruano Fernández Yaima 
Published: January 2024

La calidad de la educación es un tema que ha cobrado mucha relevancia en los últimos tiempos; ha sido tanto así, que en muchos países se ha definido como política de estado; lo que ha llevado a los sistemas educativos a redefinir conceptos y modelos, rediseñar procesos, y procedimientos y establecer nuevos indicadores de evaluación; acorde con las nuevas tendencias que impone el desarrollo social, científico y tecnológico, alcanzado por la humanidad. Sin embargo, la calidad educativa para muchos sigue siendo un tema polémico y complejo, porque está determinado conceptualmente por el momento histórico concreto que vive la sociedad, y por otro lado, está el criterio de que la calidad de la educación no puede ser evaluada por medio de una serie de estándares y criterios como un simple producto o servicio. En esta investigación se abordaron los elementos que sostienen las tendencias de la calidad en la educación, desde la gestión pedagógica; y fue resultado del proyecto de investigación desarrollado por estudiantes y docentes de la carrera de Educación Básica del Instituto Superior Universitario Espíritu Santos de la ciudad de Guayaquil, que tiene como objeto de estudio precisamente la calidad del proceso educativo, a través de la gestión pedagógica, la innovación educativa y los ambientes de aprendizaje. En el estudio se siguió una metodología cualitativa y se desarrolla a través de una investigación de revisión bibliográfica de tipo descriptiva. Con el objetivo de recopilar información relevante sobre la calidad educativa, la gestión pedagógica, la innovación educativa y los ambientes de aprendizaje, y el engranaje que existe entre estos términos, a través de una búsqueda cuidadosa de la literatura, para asumir una posición crítica y reflexiva al respecto.
Comparative Study Regarding the Design of a 3D Printed Hip Prosthesis
Authors: NECULA Silvia-Iuliana , BAȘLIU Vasile , BRIA Vasile , BODOR Marius 
Published: January 2024

This work proposes the comparison of two models of 3D printed hip prostheses, using microscopic and chemical analysis, but also compression and bending testing. The comparison was made using a hip prosthesis designed in the Autodesk Inventor 2020 program and a model freely available on the Internet. The work includes some details about the virtual prototyping of prostheses and results from the chemical analysis of the components of the hip prostheses, carried out using an X-ray spectrometer to identify the elements contained in the PETG (polyethylene terephthalate glycol) material that was used to obtain the samples. The second method of analysis was the microscopic one and finally the samples were subjected to external forces, through bending and compression testing. This comparison aimed to demonstrate the dependence between the shape of the prosthesis and the mechanical properties of the analysed samples.
Segurança do Vedolizumabe no tratamento da Retocolite Ulcerativa: Uma revisão de literatura.
Authors: Jaeger Karine Nava , Branco Maria Eduarda Mintzfels , Moura Ileana Simone de Oliveira , Viera Lorenzo Gabriel de Azevedo , Cardoso Jhoni Michael de Oliveira , Santos Caroline Bezerra Trajano dos , Araújo Carlos Galvão Branco , Silva Gabriela Priscila de Lima , Jaeger Cássia Nava , Moura Viviane Kelly de Souza , Santos Ágape Meira , Sales João Marcos Barcelos , Rabelo Flávia Larisse 
Published: January 2024

A colite ulcerativa pertence ao grupo de doenças inflamatórias intestinais, que representam patologias influenciadas por fatores genéticos e ambientais, resultando em um desequilíbrio imunológico seguido de lesões teciduais. Essas provocações ambientais desencadeiam processos inflamatórios restritos à camada mucosa do cólon, em especial no reto, podendo avançar para outras regiões. As principais intervenções terapêuticas são o manejo cirúrgico e o uso de medicamentos, como o Vedolizumabe. Este artigo tem por objetivo realizar uma varredura da literatura médica vigente sobre o tratamento da Retocolite Ulcerativa utilizando o Vedolizumabe. Trata-se de uma revisão integrativa da literatura, utilizando as bases de dados Pubmed e Biblioteca Virtual de Saúde (BVS), por meio do cruzamento dos descritores “vedolizumab”, “therapeutic” e “ulcerative colitis”, com operador booleano “AND”. As buscas resultam em 509 artigos, sendo selecionados os que coincidem com a temática em foco e excluídos o restante pela menor abrangência e fuga do tema. Dentre os critérios de inclusão, foram inseridos artigos em português, inglês e espanhol, em especial dos últimos 5 anos, resultando em 6 artigos. O fármaco Vedolizumabe possui propriedades imunossupressoras específicas ao intestino, demonstrando indicação para o tratamento da colite ulcerativa moderada a grave. Esse medicamento, apresenta ação através da sua ligação à integrina α4β7 expressa em linfócitos T intestinais, inibindo o processo inflamatório e diminuindo a sintomatologia do paciente. Assim, medidas terapêuticas por meio desse fármaco, destinada a pacientes com retocolite ulcerativa, mostra-se segura e eficaz.
Desenvolvimento de Novas Terapias para o Tratamento do Glaucoma: uma Análise Integrativa
Authors: Nascimento Arçari Cibely , Nascimento Arçari Jordana 
Published: January 2024

Este estudo examina estratégias promissoras no desenvolvimento de novas terapias para o tratamento do glaucoma, adotando uma perspectiva integrativa e inovadora. Inicialmente, são destacados os avanços nas terapias farmacológicas, enfocando potenciais agentes neuroprotetores e moduladores específicos que demonstraram eficácia na preservação da função ocular e redução da progressão da doença.
Além das abordagens farmacológicas, a análise se estende para considerar intervenções que exploram os mecanismos subjacentes ao glaucoma. A identificação de alvos moleculares e vias biológicas emergentes destaca a importância de compreender a fisiopatologia da doença para o desenvolvimento de terapias mais direcionadas.
Outro ponto de destaque aborda terapias complementares, como a otimização de estratégias de entrega de medicamentos para melhorar a eficácia e a redução de efeitos adversos. A análise inclui discussões sobre sistemas de liberação prolongada, formulações inovadoras e abordagens cirúrgicas minimamente invasivas, representando avanços significativos na busca por tratamentos mais eficazes e toleráveis.
Paralelamente, são consideradas terapias que visam não apenas a redução da pressão intraocular, mas também a preservação e regeneração do tecido ocular danificado. Isso envolve a exploração de abordagens regenerativas, como terapias celulares e fatores de crescimento, destacando sua promissora contribuição para a restauração da saúde ocular.
Além das inovações terapêuticas, este trabalho sublinha a necessidade de uma compreensão abrangente do glaucoma, incluindo fatores genéticos, metabólicos e ambientais que influenciam a resposta individual às terapias propostas. A ênfase na personalização das intervenções destaca a complexidade da doença e a importância de considerar as características individuais dos pacientes.
Ao final, destaca-se a importância de uma abordagem multidisciplinar, integrando diferentes modalidades terapêuticas para otimizar os resultados no tratamento do glaucoma. A combinação de abordagens farmacológicas inovadoras, estratégias de entrega avançadas e terapias regenerativas emerge como uma perspectiva promissora para enfrentar esse desafio oftalmológico de forma abrangente e eficaz.
THE EFFECT OF USING PICTIONARY GAMES ON STUDENTS’ VOCABULARY MASTERY
Authors: Yelvia Erli , Syafitri Widya , Kardena Absharini , Dewi Merry Prima 
Published: January 2024

This research was conducted since most of the students still had problems in learning English, especially in vocabulary mastery. Most of the students had difficulties mastering vocabulary, lack of practice in English and students were not motivated to study English. Thus, this research aimed at finding out the effect of using Pictionary Game on students’ Vocabulary Mastery in seventh grade in SMPN 2 Bukittinggi. A quasi-experimental design was used in this study. This study employed two classes: experimental and control. The population was drawn from SMPN 2 Bukittinggi seventh-grade students. In this study, the sample was 28 students from the control group and 31 students from the experimental group. To analyze the data collection procedure, a t-test formula was used. According to the results for the experiment class's pre-test and post-test scores, the t-obtained (12,92) was greater than the t-table (2,042) with the degree of freedom (df) 30 and (0,025). The t- obtained in the calculation of the post-test for both classes was (2,011), which was higher than the t-table (1,672) with (df) 57 and =0,05. So, it can be concluded that the entire hypothesis were accepted. It has been indicated that using a Pictionary game can assist students in improving their vocabulary mastery.
THE ANALYSIS OF STUDENTS’ LINGUISTICS ERROR IN MAKING PASSIVE VOICE
Authors: Deva Sri , Syafitri Widya , Syahrul Syahrul , Irwandi Irwandi 
Published: January 2024

The purpose of this study was to identify the types of linguistics errors and to analyze the causes of the students’ errors in making passive voice at XI Grade of SMK Swasta Pembina Bangsa. Several issues with students' linguistics passive voice were discovered in the field. They were students' difficulty to apply passive voice patterns into different tenses. The next problem was that some students have difficulty distinguishing between active and passive voice because they had less practice outside the classroom. This study used mix research. The participants in this study was the students of the hotel accommodation program and accounting SMK S Pembina Bangsa students in the eleventh grade. To collect the data, the researcher used a test and interviews with students. Based on calculated the data, the result showed that the total errors is 496 errors which were classified into 4 types: omission is 62 cases (12,5%), addition was 116 cases (23,38%), misformation was 155 cases (31, 25%), and misordering was 163 cases (32,86%). As a result, many students made errors in making passive voice related to some items which were caused by some factors: interlingual transfer and intralingual transfer.
Hubungan Pengetahuan Dengan Penerapan Teknik Menyusui Yang Benar Pada Ibu Postpartum Di Wilayah Kerja Puskesmas Malangke
Authors: Aoka Irmayanti , Resky Resky , Bagenda Eka Fadilah 
Published: January 2024

Permasalahan pemberian ASI bukan hanya dikaitkan akan pengetahuan dan teknik menyusui yang masih kurang dipahami oleh seorang ibu tetapi juga dikarenakan kondisi emosional yang dialami seorang Ibu Postpartum. Untuk mengetahui hubungan pengetahuan dengan penerapan teknik menyusui yang benar pada ibu postpartum di wilayah kerja Puskesmas Malangke. Desain penelitian menggunakan cross sectional. Populasi berjumlah 57 orang dan sanpel sebesar 50 orang. Teknik sampling menggunakan puposive sampling dan menggunakan uji Chi-square. Karakteristik responden sebagian besar berumur 21-30 tahun yaitu sebanyak 28 orang (56%), pendidikan tamat SMA sebanyak 25 orang (50%), dan pekerjaan sebagai IRT berjumlah 46 orang (92%). Pengetahuan ibu kurang baik tentang teknik menyusui yang benar 26 orang (52%), sedangkan pengetahuan ibu baik tentang teknik menyusui yang benar berjumlah 24 orang (48%). Ibu postpartum yang tidak melakukan penerapan teknik menyusui yang benar pada anaknya berjumlah 27 orang (54%), sedangkan ibu postpartum yang mengetahui penerapan teknik menyusui yang benar pada anaknya berjumlah 23 orang (46%). Ada hubungan pengetahuan dengan penerapan teknik menyusui yang benar ibu postpartum di wilayah kerja Puskesmas Malangke, dengan p-value : 0,007 < ? : 0,05 sehingga Ho ditolak.
Comparative Analysis of the Inhibitory Efficacy of 50% and 80% Concentrations of Rambutan Seed Extract (Nephelium lappaceum L.) on the Growth of Candida albicans
Authors: Wijaya Cindy Denhara , Daryono  , Rasyika Adani  
Published: January 2024

Introduction. Denture stomatitis is a prevalent issue among those who wear dentures, and it is caused by Candida albicans. Ketoconazole, an azole antifungal medication, is commonly employed to treat denture stomatitis. However, it is important to note that the usage of this agent might lead to hepatotoxicity and the development of resistance. The objective of the study was to assess the inhibitory efficacy of rambutan seed extract (Nephelium lappaecum L.) at concentrations of 50% and 80% on the proliferation of Candida albicans.
Methods. This research employs a laboratory experiment using a design that includes a post-test only control group. The specimen is an uncontaminated culture isolation of Candida albicans. This study had four distinct groups: rambutan seed extract concentrations of 50% and 80%, a positive control group, and a negative control group. Each group was reproduced six times. Using digital calipers to measure the diameter of resistance. Upon completion of data collection, the acquired data was subsequently subjected to analysis utilizing one-way ANOVA and post hoc LSD statistical testing.
Results. The research findings indicate that the average ± standard deviation inhibitory diameter of rambutan seed extract was 50%, 80%, and the positive control for the growth of Candida albicans was 8.68 ± 0.585; 12.38±0.505; 22.43 ± 0.809 mm, respectively. In contrast, the negative control (DMSO) did not exhibit any inhibitory effects. The one-way ANOVA test revealed a statistically significant difference in the mean inhibitory diameter of rambutan seed extract at concentrations of 50% and 80% on the growth of Candida albicans (p=0.000; p?0.05). The findings of the LSD post hoc test indicated a significant difference in inhibitory power between the 50% and 80% concentrations of rambutan seed extract, as well as between these concentrations and both the positive and negative controls. Additionally, there was a significant difference in the growth of Candida albicans between the 50% and 80% concentrations of rambutan seed extract (p?0.05).
Conclusion. The research findings indicate that the extract derived from rambutan seeds effectively inhibits the development of Candida albicans. An 80% concentration is the optimal concentration for maximum effectiveness.
Enteropatía Biliar y su Tratamiento Quirúrgico, Íleobiliar Caso Inusual de Obstrucción Intestinal, Reporte de Caso
Authors: Pons Taracena José Enrique , Valverde Leyva Eduardo Isabel 
Published: January 2024

El íleo biliar es una complicación infrecuente, caracterizada por datos clínicos de oclusión intestinal, siendo el 4% de las causas de obstrucción intestinal en la población en general. El diagnóstico es clínico e imagenologico(tríada de rigler). El manejo al principio será conservador, sin embargo, al no tener adecuada evolución se requiere de intervención quirúrgica, siendo la enterotomía con extracción de cálculos la piedra angular. El objetivo de este reporte es presentar un caso de oclusión intestinal causado íleo biliar tratado mediante laparotomía + enterotomía, extracción de lito y cierre primario. Se presenta el caso de una mujer de 69 años, mediante radiografía abdominal, colangioresonancia y tomografía abdominopelvica simple, se detectó enterocolito en íleon distal con datos de oclusión intestinal sin mejoría de tratamiento conservador. Se concluye que este diagnóstico es raro, pero de suma importancia en su diagnóstico para un abordaje terapéutico efectivo. Gallstone ileus is a rare complication, characterized by clinical data of intestinal occlusion, accounting for 4% of the causes of intestinal obstruction in the general population. Diagnosis is clinical and imaging (Rigler's triad. Management will be conservative at first, however, due to not having an adequate evolution, surgical intervention is required, with enterotomy with stone extraction being the cornerstone. The objective of this report is to present a case of gallstone ileus treated by laparotomy + enterotomy, stone extraction and primary closure. The case of a 69-year-old woman is presented, by abdominal radiography, magnetic resonance cholangiography and simple abdominopelvic tomography, enterocolith was detected in the distal ileum with data of intestinal occlusion without improvement of conservative treatment. It is concluded that this diagnosis is rare, but of great importance in its diagnosis for an effective therapeutic approach.
Effectiveness of tibio-talo-calcaneal arthrodesis for Charcot ankle arthropathy: Unraveling the impact of glycated hemoglobin on postoperative recovery and complications
Authors: Toreih Ahmed A , Abdelbadie Ahmed , El-Adawy Moawed F 
Published: January 2024

Abstract

Background
Charcot arthropathy of the ankle is a severe complication of diabetes that can lead to deformity, ulcers, and amputation. Tibio-talo-calcaneal arthrodesis is a surgical technique to stabilize the ankle, but optimal management remains unclear.

Objective
This study aimed to evaluate the functional and radiological effectiveness of tibio-talo-calcaneal arthrodesis using retrograde intramedullary nailing without bone graft for Charcot ankle and achieve stable aligned ankle construct.

Patients and methods
In this prospective study, 31 diabetic patients Eichenholtz stages 2–3 (coalescence or reconstruction phases) Charcot ankle underwent tibio-talo-calcaneal arthrodesis with retrograde nail. The American Orthopedic Foot & Ankle Society ankle-hindfoot score measured outcomes at baseline, 6 months, and 12 months postoperatively. Complications were recorded. Regression analysis identified outcome predictors.

Results
American Orthopedic Foot & Ankle Society scores improved significantly from 17.4 ± 2.37 preoperatively to 73.4 ± 10.5 at 6 months and 81.9 ± 11.5 at 12 months (P<0.001). Twelve (38.7%) patients experienced complications including deep vein thrombosis and sepsis. Elevated glycated hemoglobin predicted complications (odds ratio=3.25, P=0.010) and longer recovery (B=1.353, P=0.008). An glycated hemoglobin cutoff of 8.0% predicted complications with 75.0% sensitivity and 78.9% specificity (area under the curve=0.816).

Conclusion
Tibio-talo-calcaneal arthrodesis effectively improved ankle function in Charcot arthropathy but complications were common, emphasizing the importance of perioperative glycemic control.
A systematic review of endoprosthetic replacement versus cement spacer in reconstruction of proximal humerus following proximal humerus metastasis
Authors: Helmy Abdel R M A , Zaki Mina S , El Masry Ayman M 
Published: January 2024

Abstract

Background
The choice between cement spacer and endprosthesis in the treatment of metastatic lesions to the proximal humerus is increasingly controversial. However, it may be easier to categorize the patients, and their socioeconomic and perioperative parameters into two groups.

Aim
This work aims to review the available literature on the topic of endoprosthetic replacement versus cement spacer in the reconstruction of the proximal humerus following metastatic lesions to the proximal humerus regarding the surgical technique, its indications, its advantages, and limitations.

Patients and methods
We followed the preferred reporting items for systematic review and Meta-analysis (PRISMA) statement guidelines during this systematic review and performed all steps according to the Cochrane Handbook of Systematic Reviews of Intervention.

Results
Four studies were included in this systematic review, and a total of 100 patients were included (22 of which had cement spacer and 78 had endprosthesis). Several parameters were compared in the reviewed studies including the MSTS score of the patients; the primary tumor; postoperative complications; the patients’ age; follow-up periods; and the presenting symptoms of the patients.

Conclusion
This systematic review suggests that the cement spacer technique is not inferior to endoprosthetic replacement of the proximal humerus in cases of metastases. Therefore, we suggest that determining whether to use an end prosthesis or a cement spacer depends on categorizing the patients into two groups. Endoprosthetic replacement will be an appropriate choice for patients with preserved deltoid and axillary nerve function following resection, solitary and nonaggressive metastatic lesion, and long-life expectancy with minimal co-morbidities. We believe that cement spacer is a more appropriate choice in patients with nonfunctioning deltoid or axillary nerve following resection; multiple and aggressive metastatic lesions; short life expectancy with many co-morbidities, and poor socioeconomic status.
Expert tibial nail (ETN) versus minimally invasive plate osteosynthesis techniques in the treatment of distal tibia fractures in young adults: A randomized controlled trial
Authors: Zawam Sherif H , Bedair Mohammed A , Eldin Alaa E M , Nagy Mohamed 
Published: January 2024

Abstract

Purpose
To compare anatomical locked plates inserted in a minimally invasive pattern (MIPO) versus expert tibial nailing (ETN) for fixation of extra-articular fractures of the distal tibia in young adults.

Patients and methods
The study included 120 patients, 84 males and 36 females. The mean follow-up time was 13.5 months, with at least 12 months of follow-up. Cases were equally divided and randomized by the closed-envelope technique into two groups, group A: fixed by anatomical locked plate through a minimally invasive approach, and group B: fixed by ETN.

Results
The average operative time was significantly higher in the MIPO group (94 min) compared with the ETN group (81.67 mins). Also, the radiological exposure time was also higher (87.6 secs) in group A versus 78.4 in group B. Although there was an incidence of deformity in few cases of the ETN group (eight patients), that was not significant enough to warrant correction by revision surgery. There were no significant differences in the union time (P value: 0.09) and American Orthopedic Foot and Ankle Society (AOFAS) scores (P value: 0.78) between the two groups. Furthermore, the infection and the need for further surgeries did not show significant differences among both groups.

Conclusion
Both MIPO and ETN are valid treatment options for distal tibia fractures, AO type 43 A. Both methods resulted in acceptable union time, and American Orthopedic Foot and Ankle Society scores, with no reported cases of nonunion.
Level of evidence.
Therapeutic study, level I