bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marital status and happiness during the COVID‐19 pandemic
Authors: Liu Hui , Hsieh Ning 
Published: November 2023

AbstractObjectiveThis study examines the long‐observed marital advantage in happiness during the COVID‐19 pandemic.BackgroundThe COVID‐19 pandemic may have altered the marital advantage in happiness due to changes in social integration processes. However, this has not been explored in previous studies.MethodData were from the COVID‐19 substudy of the National Social Life, Health, and Aging Project (N = 2622). A series of regressions were estimated to understand marital status differences in pandemic happiness and changes in relationships with nonresident family and friends. Karlson–Holm–Breen mediation analysis was conducted to examine whether relationships with nonresident family and friends explained the marital association with pandemic happiness.ResultsFrom pre‐pandemic to pandemic, married respondents experienced a greater increase in unhappiness than unmarried counterparts, narrowing happiness gaps. However, unmarried individuals, including cohabiting, divorced, widowed, and never married individuals, continued to report higher levels of unhappiness during the pandemic than married peers. These differences primarily stemmed from pre‐pandemic happiness. After controlling for pre‐pandemic happiness, cohabiting, widowed, and never married older adults did not significantly differ from their married counterparts in reporting unhappiness during the pandemic. In contrast, divorced individuals remained consistently more unhappy than married individuals during the pandemic, mainly due to deteriorated relationship quality with nonresident family.ConclusionDuring a global crisis, it is crucial for policymakers, healthcare providers, and researchers to develop innovative interventions to promote happiness and healthy aging among all older adults, paying special attention to those who are divorced.
Managing the “Downside” of Downsizing: Firms' Impression Offsetting around Downsizing Announcements
Authors: Brauer Matthias , Vandepoele Louis 
Published: November 2023

AbstractPast studies indicate that investors perceive workforce downsizing negatively, as evidenced by negative short‐term stock returns around downsizing announcements. Impression management theory suggests that downsizing firms thus attempt to offset investors’ negative impressions by issuing positive news around downsizing announcements, and that firms’ impression offsetting can attenuate investors’ negative response. In this study, we test these theoretical predictions but also unpack why and how impression offsetting positively biases investor perceptions. Prior work theorized that impression offsetting is effective because it dilutes investors’ attention and compels them to average positive and negative news items in their minds but did not clarify whether both causal mechanisms are operative, and which one is more powerful. We posit that impression offsetting influences investor response primarily by forcing them to mentally average positive and negative news. Further, our study provides a more nuanced understanding of investors’ mental averaging process. While prior work assumed that all types of positive news are received equally by investors, we argue that positive financial news offsets investors’ negative impressions more effectively than positive operational or social news. The empirical analysis of nearly 1500 downsizing announcements by the largest, public US firms between 2001 and 2020 mainly supports our theoretical reasoning.
How Do Innovation Ecosystems Emerge? The Case of Nanotechnology in Israel
Authors: Drori Issy , Lavie Dovev 
Published: November 2023

AbstractResearch on innovation ecosystems has identified their evolution phases but neglected their emergence, which we know little about. We offer inductive theory to explain the emergence of the nanotechnology ecosystem in Israel. Our theory suggests that ineffective bureaucracy, resource constraints, and the conflicting agendas of the government and universities create organizational bottlenecks that impede the ecosystem's emergence. Only once these actors establish related dedicated units that are immune to these deficiencies and transition to simultaneous competition and cooperation does the innovation ecosystem begin to emerge. We further reveal how enabling and governing mechanisms legitimize the innovation ecosystem, facilitate its emergence, and direct its evolution trajectory. Hence, we extend research that has centered on subsequent phases of evolution and explain how actors interact to facilitate the emergence of the ecosystem following technological discovery. Our study contributes to strategy research on interfirm coopetition by applying this concept to government and university actors, and by alluding to its multiple facets: identity, direction, administration, and resources. We also complement innovation research on the post‐formation dynamics of ecosystems by providing insights into the missing link between technological discovery and the creation of an innovation ecosystem that brings together stakeholders to commercialize that technology.
Defense styles, well‐being, and functional disability in the African context: A structured interview‐based study
Authors: Marchetti Igor , Micheli Ilaria , Grassi Michele 
Published: November 2023

AbstractObjectiveWe investigated the defense styles in the African context by exploring their internal structure in Burkinabé individuals. Moreover, we explored how defense styles were related to sociocultural variables. Finally, we tested whether defense styles could mediate the relationship between sociocultural variables and mental well‐being as well as functional disability.MethodThe study recruited 998 individuals (66.9% male; age = 25.50 ± 7.8 years) living in Burkina Faso. Standard measures for defense mechanisms, mental well‐being, and functional disability were administered as a structured interview in the local vehicular language, that is, Dyula.ResultsPrincipal component analysis identified three major defense styles—mature, neurotic, and immature. Gender, formal education, living area, and believing in traditional practices were associated with any of the three defense styles. Moreover, the immature style mediated the impact of sociocultural variables on specific outcomes, such as higher functional disability and lower mental well‐being. The neurotic style was associated with lower functional disability, while the mature style was not associated with any of the outcome variables.ConclusionOur study provided preliminary support to the notion that defense styles may function similarly across cultures and they are likely reactive to the sociocultural context.
A reciprocal relationship between parental maltreatment and child bullying perpetration in China
Authors: Wu Wei , Xie Ruibo , Ding Wan , Ding Dan , Tan Deqin , Song Shengcheng , Li Weijian 
Published: November 2023

AbstractThis study aimed to examine the longitudinal reciprocal relationship between parental maltreatment and child bullying perpetration from middle childhood to early adolescence in China and the associated gender differences. Eight hundred ninety‐one children completed a battery of questionnaires at four time points. A random‐intercept cross‐lagged model was established. The results indicated that at the between‐person level, child bullying perpetration was positively associated with physical and psychological maltreatment. At the within‐person level, there was a significant association between an increase in bullying perpetration and an increase in parental psychological and physical maltreatment across the four time points. Conversely, an increase in physical maltreatment led to an increase in child bullying perpetration from T1 to T2, while an increase in psychological maltreatment resulted in an increase in child bullying perpetration from T1 to T2 and T2 to T3. Furthermore, an increase in physical maltreatment increased boys' bullying perpetration but decreased that in girls from T2 to T3. These findings provide inspiration for future family education and anti‐bullying interventions in schools.
Algae in the Anthropocene: Managing, conserving, and utilizing algae in an era of rapid environmental change
Authors: Coleman Melinda A. 
Published: November 2023

AbstractThe Anthropocene is defined as the current period in which humans have had a large influence over the status and trajectory of earth's climate and environment. Human‐induced climate change, pollution, and coastal development have caused major changes to algal persistence, distribution, diversity, and function. This has not only brought new challenges for managing and conserving algae, but also new opportunities. This series of perspective pieces will touch on some of these challenges, potential solutions, and knowledge gaps that we must consider in supporting and understanding algae in the Anthropocene.
Elucidating the molecular healing of intrabony defects following non‐surgical periodontal therapy: A pilot study
Authors: Koidou Vasiliki P. , Hagi‐Pavli Eleni , Nibali Luigi , Donos Nikolaos 
Published: November 2023

AbstractObjectiveTo elucidate the molecular healing of intrabony defects following non‐surgical periodontal therapy (NSPT) using gingival crevicular fluid (GCF).Background DataCurrently limited information is available regarding the GCF of intrabony defects and the change in biomarker levels in the GCF at early time points following treatment interventions.MethodsTwenty‐one patients (Periodontitis Stage III or IV) who have received NSPT, contributing one intrabony defect and one healthy site were included in this study. GCF sampling was performed at baseline, 1 day, 5 days and 3 months after NSPT. Multiplex bead immunoassays allowed the profiling of GCF for 27 markers, associated with inflammation and repair/regeneration. A mixed effects model with Bonferroni correction for multiple comparisons was employed to compare the changes in the levels of GCF markers over time.ResultsFollowing NSPT, changes were observed for several GCF markers, marked by significant increases 1 day post‐intervention, before returning to baseline levels by 3 months. Specifically, GCF concentrations of IL‐2, IL‐4, IL‐6, IL‐8, MMP‐1, MMP‐3, TIMP‐1 and FGFb significantly increased 1 day after NSPT. Signs of activation of cellular senescence were observed 1 day following treatment of intrabony defects, rapidly regressing by 5 days.ConclusionSignificant molecular changes are observed as early as 1 day following NSPT in intrabony defects, along with activation of cellular senescence.
The European Insomnia Guideline: An update on the diagnosis and treatment of insomnia 2023
Authors: Riemann Dieter , Espie Colin A. , Altena Ellemarije , Arnardottir Erna Sif , Baglioni Chiara , Bassetti Claudio L. A. , Bastien Celyne , Berzina Natalija , Bjorvatn Bjørn , Dikeos Dimitris , Dolenc Groselj Leja , Ellis Jason G. , Garcia‐Borreguero Diego , Geoffroy Pierre A. , Gjerstad Michaela , Gonçalves Marta , Hertenstein Elisabeth , Hoedlmoser Kerstin , Hion Tuuliki , Holzinger Brigitte , Janku Karolina , Jansson‐Fröjmark Markus , Järnefelt Heli , Jernelöv Susanna , Jennum Poul Jørgen , Khachatryan Samson , Krone Lukas , Kyle Simon D. , Lancee Jaap , Leger Damien , Lupusor Adrian , Marques Daniel Ruivo , Nissen Christoph , Palagini Laura , Paunio Tiina , Perogamvros Lampros , Pevernagie Dirk , Schabus Manuel , Shochat Tamar , Szentkiralyi Andras , Van Someren Eus , van Straten Annemieke , Wichniak Adam , Verbraecken Johan , Spiegelhalder Kai 
Published: November 2023

SummaryProgress in the field of insomnia since 2017 necessitated this update of the European Insomnia Guideline. Recommendations for the diagnostic procedure for insomnia and its comorbidities are: clinical interview (encompassing sleep and medical history); the use of sleep questionnaires and diaries (and physical examination and additional measures where indicated) (A). Actigraphy is not recommended for the routine evaluation of insomnia (C), but may be useful for differential‐diagnostic purposes (A). Polysomnography should be used to evaluate other sleep disorders if suspected (i.e. periodic limb movement disorder, sleep‐related breathing disorders, etc.), treatment‐resistant insomnia (A) and for other indications (B). Cognitive‐behavioural therapy for insomnia is recommended as the first‐line treatment for chronic insomnia in adults of any age (including patients with comorbidities), either applied in‐person or digitally (A). When cognitive‐behavioural therapy for insomnia is not sufficiently effective, a pharmacological intervention can be offered (A). Benzodiazepines (A), benzodiazepine receptor agonists (A), daridorexant (A) and low‐dose sedating antidepressants (B) can be used for the short‐term treatment of insomnia (≤ 4 weeks). Longer‐term treatment with these substances may be initiated in some cases, considering advantages and disadvantages (B). Orexin receptor antagonists can be used for periods of up to 3 months or longer in some cases (A). Prolonged‐release melatonin can be used for up to 3 months in patients ≥ 55 years (B). Antihistaminergic drugs, antipsychotics, fast‐release melatonin, ramelteon and phytotherapeutics are not recommended for insomnia treatment (A). Light therapy and exercise interventions may be useful as adjunct therapies to cognitive‐behavioural therapy for insomnia (B).
Assessing socio‐environmental suitability and social license of proposed offshore aquaculture development: A Florida case study
Authors: Guthrie Amanda G. , Barbour Nicole , Cannon Sara E. , Marriott Sara E. , Racine Phoebe , Young Ruth , Bae Ashley , Lester Sarah E. , Michaelis Adriane 
Published: November 2023

AbstractOffshore aquaculture is a growing industry, but a lack of social acceptance is limiting development, including within the USA. We used the Gulf Coast of Florida, where there has been industry and government interest in development, as a case study to explore offshore aquaculture potential and methods for integrating stakeholder concerns into offshore aquaculture development. We assessed (1) social acceptance of offshore aquaculture in the Florida Gulf Coast using public comments; (2) site suitability for offshore development using social, biological, and technical data; and (3) potential impacts of offshore aquaculture on communities using socioeconomic vulnerability indices. We found that many stakeholders distrust policymakers and industry and have concerns about potential environmental impacts. We created species‐specific suitability maps for red drum (Sciaenops ocellatus) and almaco jack (Seriola rivoliana), demonstrating that large areas of the Gulf are suitable for offshore aquaculture development. We show that many coastal and fishing‐reliant communities have existing vulnerabilities that aquaculture development could affect, but the public comments did not reflect these. To gain social acceptance, industry and government agencies will need to better incorporate public feedback into planning processes in a meaningful way. Consulting local communities and adapting projects in response to their concerns can help to secure social license for offshore aquaculture.
Golexanolone improves fatigue, motor incoordination and gait and memory in rats with bile duct ligation
Authors: Arenas Yaiza M. , Izquierdo‐Altarejos Paula , Martinez‐García Mar , Giménez‐Garzó Carla , Mincheva Gergana , Doverskog Magnus , Jones David E. J. , Balzano Tiziano , Llansola Marta , Felipo Vicente 
Published: November 2023

AbstractBackground and AimsMany patients with the chronic cholestatic liver disease primary biliary cholangitis (PBC) show fatigue and cognitive impairment that reduces their quality of life. Likewise, rats with bile duct ligation (BDL) are a model of cholestatic liver disease. Current PBC treatments do not improve symptomatic alterations such as fatigue or cognitive impairment and new, more effective treatments are therefore required. Golexanolone reduces the potentiation of GABAA receptors activation by neurosteroids. Golexanolone reduces peripheral inflammation and neuroinflammation and improves cognitive and motor function in rats with chronic hyperammonemia. The aims of the present study were to assess if golexanolone treatment improves fatigue and cognitive and motor function in cholestatic BDL rats and if this is associated with improvement of peripheral inflammation, neuroinflammation, and GABAergic neurotransmission in the cerebellum.MethodsRats were subjected to bile duct ligation. One week after surgery, oral golexanolone was administered daily to BDL and sham‐operated controls. Fatigue was analysed in the treadmill, motor coordination in the motorater, locomotor gait in the Catwalk, and short‐term memory in the Y‐maze. We also analysed peripheral inflammation, neuroinflammation, and GABAergic neurotransmission markers by immunohistochemistry and Western blot.ResultsBDL induces fatigue, impairs memory and motor coordination, and alters locomotor gait in cholestatic rats. Golexanolone improves these alterations, and this was associated with improvement of peripheral inflammation, neuroinflammation, and GABAergic neurotransmission in the cerebellum.ConclusionGolexanolone may have beneficial effects to treat fatigue, and motor and cognitive impairment in patients with the chronic cholestatic liver disease PBC.
Navigating portal hypertension: Unlocking safe passage to healthy pregnancy in EHPVO
Authors: Shukla Akash , Singh Ankita , Saxena Akriti , Panda Saurav , Mane Prajakta , Khan Nagma , Harindranath Sidharth , Vaidya Arun , Kuruthukulangara Michael , Mayadeo Niranjan 
Published: November 2023

AbstractBackground and AimsPregnancy is associated with hyperdynamic circulatory state and increased risk of portal hypertension related complications in patients with extra‐hepatic portal vein obstruction (EHPVO). We aim to study the impact of EHPVO on pregnancy‐related outcomes with focus on subset of patients with UGIB (upper GI bleed).MethodsRetrospective analysis of obstetric, maternal and neonatal outcomes of patients with EHPVO registered between January 2006 and December 2022. Forty‐five patients were included. Forty‐five healthy females with low‐risk pregnancies formed the control group.ResultsAdverse obstetric and neonatal outcomes were comparable between EHPVO and control group (22% vs. 28.6%; p > .05; low birth weight/ small for gestational age 17.8% vs. 36%, p = .0918 and 14.2% vs. 10%, p = .5698 respectively). Adverse outcomes were similar in patients with and without history of UGIB (26.3% vs. 19.4%, p = .0814; 17.8% vs. 36%, p = .0918; 14.2% vs. 10%, p = .5698). There was no maternal mortality in both the groups. A total of 7% pregnancies in EHPVO patients were complicated by ascites.ConclusionsEHPVO pregnancies have successful obstetric and neonatal outcomes with adequate management of portal hypertension.
The impact history and prolonged magmatism of the angrite parent body
Authors: Rider‐Stokes B. G. , Anand M. , White L. F. , Darling J. R. , Tartèse R. , Whitehouse M. J. , Franchi I. , Greenwood R. C. , Degli‐Alessandrini G. 
Published: November 2023

AbstractAs some of the oldest differentiated materials in our solar system, angrite meteorites can provide unique insights into the earliest stages of planetary evolution. However, the timing of planetary mixing, as evidenced by oxygen isotope variations in the quenched angrites, and the extent of magmatism on the angrite parent body (APB) remain poorly understood. Here, we report on microstructurally guided in situ geochemical and Pb–Pb isotopic measurements on angrites aimed at better understanding of the timing and nature of magmatic processes, as well as impact events, on the APB. The quenched angrite Northwest Africa (NWA) 12320 yielded a Pb–Pb date of 4571.2 ± 9.4 Ma, which we interpret as corresponding to the timing of planetary mixing. The only known shocked quenched angrite, NWA 7203, also yielded an ancient Pb–Pb date of 4562.9 ± 9.3 Ma, which is identical to the Pb–Pb date of 4563.6 ± 7.9 Ma obtained for the texturally intermediate angrite NWA 10463. Pb–Pb analyses in phosphates in the dunitic angrite NWA 8535 yielded a much younger date of 4514 ± 30 Ma, representing the youngest Pb–Pb date ever recorded for an angrite. Based on the evidence from the lack of shock deformation, olivine major and trace element compositions, and no apparent contamination in the oxygen isotope composition of NWA 8535, our findings are consistent with prolonged magmatism on the APB. This finding is consistent with a large size for the APB.
New indicators for monitoring genetic diversity applied to alpine brown trout populations using whole genome sequence data
Authors: Kurland Sara , Saha Atal , Keehnen Naomi , de la Paz Celorio‐Mancera Maria , Díez‐del‐Molino David , Ryman Nils , Laikre Linda 
Published: November 2023

AbstractInternational policy recently adopted commitments to maintain genetic diversity in wild populations to secure their adaptive potential, including metrics to monitor temporal trends in genetic diversity – so‐called indicators. A national programme for assessing trends in genetic diversity was recently initiated in Sweden. Relating to this effort, we systematically assess contemporary genome‐wide temporal trends (40 years) in wild populations using the newly adopted indicators and whole genome sequencing (WGS). We use pooled and individual WGS data from brown trout (Salmo trutta) in eight alpine lakes in protected areas. Observed temporal trends in diversity metrics (nucleotide diversity, Watterson'sϴand heterozygosity) lie within proposed acceptable threshold values for six of the lakes, but with consistently low values in lakes above the tree line and declines observed in these northern‐most lakes. Local effective population size is low in all lakes, highlighting the importance of continued protection of interconnected systems to allow genetic connectivity for long‐term viability of these populations. Inbreeding (FROH) spans 10%–30% and is mostly represented by ancient (<1 Mb) runs of homozygosity, with observations of little change in mutational load. We also investigate adaptive dynamics over evolutionarily short time frames (a few generations); identifying putative parallel selection across all lakes within a gene pertaining to skin pigmentation as well as candidates of selection unique to specific lakes and lake systems involved in reproduction and immunity. We demonstrate the utility of WGS for systematic monitoring of natural populations, a priority concern if genetic diversity is to be protected.