bluuebunny/crossref_metadata_2025_split huggingface dataset:
ACHIEVEMENTS IN PHYSICAL CHEMISTRY IN THE FIELD OF MICROSCOPY AND VISUALIZATION OF NANOSYSTEMS
Authors: Ogenko Volodymyr 
Published: December 2023

The review presents modern views and the history of the development of microscopic studies of nanosystems which heve been started 2014, after the Nobel Prize in Chemistry was awarded to Eric Betzig, William Mörner, and Stefan Gell "for the development of super-resolved fluorescence microscopy". Their work ushered in a new era of optical microscopy, enabling the precise examination of individual molecules and molecular clusters by using optical microscopes. By circumventing the diffraction limitations that had constrained traditional optical microscopes, scientists gained access to the nanoscale realm, investigating structures within the 1–100 nanometer range. Special attention is paid to the use of carbon quantum dots and plasmon resonance to enhance fluorescence when obtaining the effect of super-resolution images, which allow the use of optical microscopes in the estimation of the sizes of cluster and single molecules. This breakthrough in removing the diffraction li­mitation allowed scientists to use the working range of 1–100 nm and obtain 3D images of nanosystems and images of living cells. Particular attention is paid to the achievements and prospects of high-resolution fluorescent nanoscopy SRM, which is successfully deve­lo­ping and studying the nanoworld in the range of 1–100 nm at the level of scanning electron microscopy. In cell biology, nanomedicine, etc. are developing roadmaps for scientific breakthroughs in super-resolution visualization me­thods for "live" images. Prospects of Immuno-­SERS microscopy and medicine of indivi­dual diagnosis are considered
Key Findings:

This article highlights the achievements and future prospects of super-resolution fluorescence microscopy SRM.
High-resolution fluorescence microscopy has proven instrumental in advancing our understanding of the living world within the 1–100 nanometer range, which is akin to the capabilities of scanning electron microscopy.
Within the domains of cell biology and nanomedicine, roadmaps for scientific breakthroughs are emerging, fueled by super-re­so­lution imaging techniques, providing "live" insights into cellular processes.
The horizons of Immuno-SERS Microscopy and Personalized Diagnostics Medicine are expanding, promising exciting prospects in the field of medical diagnostics.
SELF EFFICACY MAHASISWA KURANG MAMPU DI KOTA MAKASSAR
Authors: Nur Awal Muh. , Jermias Emanuel Omedetho , Rahman Abdul 
Published: December 2023

Penelitian ini mengkaji tentang pentingnya Self Efficacy ditanamkan dalam kehidupan sebagai suatu untuk mendorong motivasi dalam berbagai bidang serta mendorong agar individu mampu menggunakan potensi dirinya secara optimal. Self efficacy adalah variabel motivasi penting yang telah terbukti memiliki pengaruh yang cukup besar pada sejumlah hasil akademik, seperti minat individu, kinerja tugas mereka, dan jumlah upaya dan ketekunan yang bersedia mereka keluarkan saat menghadapi kesulitan. Jika didukung oleh efikasi diri yang mumpuni. self efficacy memiliki kepercayaan bahwa “saya bisa” hal ini diiringi dengan semangat yang tinggi dalam mengerjakan setiap tugas sehingga dalam setiap kegiatan yang dilakukannya berhasil dan mendapatkan hasil yang optimal khususnya kepada mahasiswa kurang mampu di Kota Makassar dalam melakukan kegiatan sehari – harinya. penelitian ini dilakukan di Kota Makassar dan berfokus pada kalangan mahasiswa yang sedang menempuh studi di perguruan tinggi. Penelitian ini menggunakan metode penelitian kualitatif deskriptif dengan pendekatan fenomenologi untuk menganalisis gejala yang terjadi.
KONDISI SOSIAL EKONOMI PEDAGANG KAKI LIMA DI PERUMAHAN MUTIARA BEKASI JAYA
Authors: Wikanti Wardah Alivia , Afrizal Stevany 
Published: December 2023

Hubungan Ibu Kota Jakarta dengan daerah penyangga di sekitarnya tak bisa dihindarkan. Padatnya Jakarta membawa dampak ke daerah penyangga sekitarnya seperti Kabupaten Bekasi. Kabupaten Bekasi menawarkan lapangan kerja yang melimpah, namun tak semua pendatang dapat terserap. Masyarakat yang tak terserap oleh perusahaan kemudian memilih pekerjaan di bidang sector informal. Pekerjaan yang mereka pilih salah satunya adalah pedagang kaki lima. Pedagang kaki lima banyak ditemui di lokasi yang ramai, salah satunya di Perumahan Mutiara Bekasi Jaya. Banyak hambatan yang ditemui oleh pedagang kaki lima seperti banyaknya saingan, pendapatan yang tak menentu dan cuaca buruk. Kondisi tersebut berpengaruh terhadap kondisi sosial ekonominya yang meliputi pendapatan, pekerjaan, kesehatan, dan kebutuhan rumah tangganya. Tujuan dari penelitian ini adalah untuk mengetahui kondisi sosial ekonomi pedagang kaki lima di Perumahan Mutiara Bekasi Jaya. Metode penelitian ini menggunakan metode kualitatif yang bersifat deskriptif. Hasil penelitian ini adalah latar belakang pendidikan dan kurangnya kemampuan menjadi alasan informan memilih pedagang kaki lima sebagai pekerjaannya, dengan pendapatan yang tidak menentu informan mengaku cukup untuk memenuhi kebutuhan sehari-harinya, PKL sangat terbantu dengan adanya layanan kesehatan gratis yang disediakan yakni BPJS dan yang terakhir informan tidak mempermasalahkan masalah saingan karena sesama pedagang harus saling berbagi rezeki.
KOLABORASI GURU DAN MAHASISWA DALAM MELAKUKAN PEMBELAJARAN LITERASI DAN NUMERASI KAMPUS MENGAJAR 4 DI SMPN 10 KOTA BIMA
Authors: Faridah Nur , Nurhasanah Nurhasanah , Tahir M. , Nurbayan ST. , Arifuddin Arifuddin 
Published: December 2023

Suatu Negara dapat dikatakan sebagai negara yang maju dapat diukur dengan. Infrastruktur yang mendukung demi terciptanya pendidikan yang baik, tetapi hingga saat ini masih banyak infrastruktur tertinggal baik dalam sarana dan prasarana, guru, akses yang terbatas terutama daerah 3T, sehingga KEMENDIKBUD mengeluarkan program Kampus merdeka untuk mengatasi persoalan diatas yakni Kampus Mengajar yang merupakan salah satu bagian program dari Merdeka Belajar Kampus Merdeka (MBKM sengan tujuan menggali potensi terbesar para guru dan siswa untuk berinovasi meningkatkan kualitas pembelajaran secara mandiri untuk membantu pembelajaran Sekolah Dasar dan Sekolah Menengah Pertama yang berstatus 3T. Menghadirkan mahasiswa untuk berkolaborasi dengan guru sebagai bagian dari penguatan pembelajaran literasi dan numerasi serta menjadi mitra guru dalam melakukan kreativitas dan inovasi dalam pembelajaran. Penelitian ini menggunakan deskripsi Analisis dengan pendekatan kualitatif. Informan penelitian sebanyak 3 orang mahasiswa dan 3 orang guru IPS serta 15 orang siswa kelas VIIa, VIIb, dan VIIc yang ditentukan secara random sampling. Tenik pengumpulan data dengan observasi, wawancara dan dokumentasi, kemudian data dianalisis dengan resuksi data, display data dan keabsahan data dan kesimpulan. Hasil penelitian menggambarkan bahwa kolaborasi guru dan mahasiswa dalam melakukan kreativitas pembelajaran literasi dan numerasi dapat dilihat dari kekompakan dalam melaksanakan pengajaran, merealisasikan adaptasi teknologi, administrasi sekolah, sehingga ketimpangan layanan dan akses pendidikan yang dialami oleh siswa-siswa dapat diatasi
RELATIONSHIP BETWEEN TECHNOLOGICAL COMPONENTS AND INVENTIVE SKILLS AMONG MALAY LANGUAGE TEACHERS
Authors: AHMAD KUSAINI Ezwafahmey , MAHAMOD Zamri , WAN MOHAMMAD Wan Muna Ruzanna 
Published: December 2023

Technology use in classroom can improve teachers’ ability to deliver effective and
relevant content. Teachers should be more prepared to apply technology to ensure that
students will have more fun and have a high interest in continuing to learn in the era of
globalisation which is based on the use of these information communication technology
elements in the classroom during the teaching and facilitation process. This study
identifies the relationship between technological knowledge, technological content
knowledge, technological pedagogical knowledge, technological pedagogical content
knowledge, and inventive skills for teachers. A total of 400 questionnaires were
distributed to teachers who taught Malay language subjects in secondary schools in
Malaysia. To test the hypothesis, the structural equation using the PLS-SEM framework
was used. The results showed that technological knowledge, technological content
knowledge, technological pedagogical knowledge, and technological pedagogical content
knowledge have a positive relationship with inventive skills for teachers.
RELATIONSHIP BETWEEN VOCABULARY ACQUISITION AND INDIVIDUAL DIFFERENCES AMONG MIDDLE SCHOOL STUDENTS
Authors: SUBON Frankie , UNIN Norseha 
Published: December 2023

This paper explores the vocabulary acquisition of 143 middle school students from an East
Malaysian school, examining its correlation with gender, attitudes, and perceived
problems faced in vocabulary learning. Using the Contextualised Word Family
(CONTEXTUALISED WORD FAMILY) model, the study tested the effectiveness of explicit
vocabulary instruction over 30 sessions. The study utilised a one-group pretest-posttest
design, measuring the learners’ vocabulary size through the Productive Vocabulary Levels
Test (PVLT) and a questionnaire. The results showed an increase in vocabulary size with
no significant difference based on gender, a very weak negative correlation with attitudes
towards vocabulary learning, and mostly weak positive but significant relationships with
three of the learners’ perceived problems faced in vocabulary learning. This study
provides some important pedagogical implications for teacher practice and
recommendations for future research.
Pengaruh Pelatihan Kepemimpinan Transformasional Kepala Ruangan terhadap Implementasi Komunikasi Efektif oleh Perawat Pelaksana
Authors: Pandie Fance Roynaldo , Riti Irlin Falde 
Published: December 2023

Salah satu penyebab masalah keselamatan pasien adalah tidak optimalnya penerapan SOP komunikasi efektif oleh perawat. Padahal kepala ruangan sebagai first line manager memiliki peran penting dalam penerapan komunikasi efektif melalui gaya kepemimpinan transformasional. Penelitian ini bertujuan untuk menganalisis pengaruh pelatihan kepemimpinan transformasional kepala ruangan terhadap implementasi komunikasi efektif oleh perawat pelaksana. Penelitian ini menggunakan rancangan pra-eksperimen dengan pendekatan one group pretest post-test design. Besar sampel dalam penelitian sebanyak 197 perawat yang dipilih dengan teknik non-probability sampling, yaitu convenience sampling. Kuesioner dengan 20 pertanyaan digunakan untuk mengukur persepsi perawat tentang gaya kepemimpinan transformasional dalam penerapan komunikasi efektif. Hasil uji Wilcoxon menunjukkan ada perbedaan yang signifikan antara implementasi komunikasi efektif sebelum dan sesudah diberikan pelatihan kepemimpinan transformasional (p value <0,001). Ada pengaruh pelatihan kepemimpinan transformasional kepala ruangan terhadap pelaksanaan komunikasi efektif oleh perawat. Gaya kepemimpinan transformasiona dapat diterapkan untuk meminimalisir kesalahan dalam penerapan SOP komunikasi efektif.
Marine biodegradation of poly[(R)-3-hydroxybutyrate-co-4-hydroxybutyrate] elastic fibers in seawater: dependence of decomposition rate on highly ordered structure
Authors: Omura Taku , Tsujimoto Sakura , Kimura Satoshi , Maehara Akira , Kabe Taizo , Iwata Tadahisa 
Published: December 2023

Here, we report the marine degradability of polymers with highly ordered structures in natural environmental water using microbial degradation and biochemical oxygen demand (BOD) tests. Three types of elastic fibers (non-porous as-spun, non-porous drawn, and porous drawn) with different highly ordered structures were prepared using poly[(R)-3-hydroxybutyrate-co-16 mol%-4-hydroxybutyrate] [P(3HB-co-16 mol%-4HB)], a well-known polyhydroxyalkanoate. Scanning electron microscopy (SEM) images indicated that microorganisms attached to the fiber surface within several days of testing and degraded the fiber without causing physical disintegration. The results of BOD tests revealed that more than 80% of P(3HB-co-16 mol%-4HB) was degraded by microorganisms in the ocean. The plastisphere was composed of a wide variety of microorganisms, and the microorganisms accumulated on the fiber surfaces differed from those in the biofilms. The microbial degradation rate increased as the degree of molecular orientation and porosity of the fiber increased: as-spun fiber &lt; non-porous drawn fiber &lt; porous drawn fiber. The drawing process induced significant changes in the highly ordered structure of the fiber, such as molecular orientation and porosity, without affecting the crystallinity. The results of SEM observations and X-ray measurements indicated that drawing the fibers oriented the amorphous chains, which promoted enzymatic degradation by microorganisms.
Expression of secreted frizzled-related proteins in acute aortic dissection patients and the effects on prognosis
Authors: Miao Huangtai , Li Xiaoying , Liang Ying , Tang Hao , Song Zihao , Nie Shaoping 
Published: December 2023

BackgroundSecreted frizzled-related proteins (SFRPs) were reported to be involved in cardiovascular diseases. This study aimed to observe plasma SFRP levels in acute aortic dissection (AD) patients and the effects of SFRP expression on AD prognosis.MethodsPlasma levels of SFRP1, SFRP2, SFRP3, SFRP4, and SFRP5 were measured in AD patients and non-AD (NAD) patients. The end-point events information of AD patients, including all-cause death and various clinical complications due to aortic dissection, was collected during a 36-month follow-up.ResultsThe SFRP1, SFRP2, SFRP3, and SFRP4 levels were increased in AD patients compared with those in NAD patients, while the SFRP5 concentrations were decreased. No differences in any of the SFRP levels were observed between the type A group and the type B group. The AD patients with end-point events exhibited higher SFRP1, SFRP2, SFRP3, and SFRP4 concentrations but lower SFRP5 levels than the patients without end-point events. In addition, the AD patients were divided into a high group and a low group based on the median SFRP levels, and Kaplan-Meier analysis revealed that the AD patients with high SFRP1, SFRP2, SFRP4, or SFRP5 levels had a better prognosis than those with low levels. However, the AD patients with high SFRP3 levels exhibited the opposite trends. The binary logistic regression analysis found that SFRP1, SFRP2, SFRP4, and SFRP5 were all negatively correlated with the occurrence of end-point events, while SFRP3 was positively correlated with its occurrence.ConclusionsSFRP levels are all changed in acute AD, which may affect the prognosis of AD patients. SFRPs may be a target to improve the prognosis of AD.
Spatial prediction of physical and chemical properties of soil using optical satellite imagery: a state-of-the-art hybridization of deep learning algorithm
Authors: Hosseini Fatemeh Sadat , Razavi-Termeh Seyed Vahid , Sadeghi-Niaraki Abolghasem , Choi Soo-Mi , Jamshidi Mohammad 
Published: December 2023

This research aimed to predict soil’s physical and chemical properties with a state-of-the-art hybrid model based on deep learning algorithms and optical satellite images in a region in the north of Iran. As dependent data, 317 soil samples (0–30 cm) were collected in field surveying and analyzed by the soil and water research institute for their physical (clay, silt, and sand) and chemical [electrical conductivity (EC), organic carbon (OC), phosphorus (P), soil reaction (pH), and potassium (K)] properties. Based on independent data, 23 remote sensing (RS) parameters (extracted from Landsat 8 optical images), 17 topographical parameters [extracted from the digital elevation model (DEM)], and four climatic parameters (derived from the meteorological organization). Spatial prediction of physical and chemical properties was implemented using a convolutional neural network (CNN), recurrent neural network (RNN), and hybrid CNN-RNN models. The evaluation results indicated that the hybrid CNN-RNN model had higher accuracy in all soil properties, followed by the RNN and CNN models. In the hybrid CNN-RNN model, pH (0.0206), EC (0.0958 dS/m), silt (0.0996%), P (0.1078 ppm), K (0.1185 ppm), sand (0.1360%), OC (0.1361%), and clay (0.1419%) had higher prediction accuracy, as determined by the root mean-squared error (RMSE) index. The hybrid CNN-RNN model proved to be the most effective for soil property prediction in this region. This finding underscores the potential of deep learning techniques in harnessing RS data for precise soil property mapping, with implications for land management and agricultural practices.
Allergic diseases aggravate the symptoms of SARS-CoV-2 infection in China
Authors: Zhang Huishan , Lin Jilei , Wu Jinhong , Zhang Jing , Zhang Lei , Yuan Shuhua , Chen Jiande , Tang Qiuyu , Zhang Ailian , Cui Yuxia , Xu Xiaojuan , Dai Hongxie , Shi Hongbo , Hu Xiaowei , Xie Dan , Chen Jing , He Fengquan , Yin Yong 
Published: December 2023

BackgroundThe relationship between allergic diseases and the adverse outcomes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection has been a subject of controversy. This study aimed to investigate the association between allergic diseases and the incidence and severity of symptoms in SARS-CoV-2 infection.MethodsClinical data of individuals, including children and their parents, infected with SARS-CoV-2 from December 2022 to January 2023 in China were retrospectively analyzed. The data were collected through questionnaires. Statistical analysis, including chi-squared tests, nonparametric analysis, one-way ANOVA, and logistic regression analysis, was used to examine the relationship between allergic diseases, prior medication, and the symptoms of SARS-CoV-2 infection.ResultsThere were 3,517 adults and 3,372 children with SARS-CoV-2 infection included in the study. Fever was found to occur at similar rates in children (86.5%) and adults (86.8%). However, other symptoms related to respiratory issues (such as cough and sore throat), neurological symptoms (headache, loss of smell, and loss of taste), and systemic symptoms (muscle soreness and weakness) were observed more frequently in adults (P &lt; 0.001). Additionally, adults exhibited higher overall symptom scores, indicating greater severity. Allergic diseases were found to be associated with the incidence of certain SARS-CoV-2 infection symptoms in both children and adults. Specifically, children with allergic rhinitis (AR) were observed to be more susceptible to upper respiratory symptoms (OR: 1.320, 95% CI: 1.081-1.611, P = 0.006), while asthma patients were found to be more susceptible to severe respiratory symptoms (OR: 1.736, 95% CI: 1.250-2.411, P = 0.001). Similar patterns were identified in adults. Furthermore, AR was also suggested to be a risk factor for symptom severity in both children (OR: 1.704, 95% CI: 1.314-2.209, P &lt; 0.001) and adults (OR: 1.736, 95% CI: 1.250-2.411, P = 0.001). However, prior medication for allergic diseases did not exhibit a preventive effect on SARS-CoV-2 infection symptoms.ConclusionsBoth children and adults with allergic diseases were found to be more prone to experiencing symptoms of SARS-CoV-2 infection, and these symptoms tended to be more severe.
The opportunities and challenges of adopting ChatGPT in medical research
Authors: Alsadhan Abeer , Al-Anezi Fahad , Almohanna Asmaa , Alnaim Norah , Alzahrani Hayat , Shinawi Reem , AboAlsamh Hoda , Bakhshwain Amal , Alenazy Maha , Arif Wejdan , Alyousef Seham , Alhamidi Sami , Alghamdi Alya , AlShrayfi Nour , Rubaian Nouf Bin , Alanzi Turki , AlSahli Alaa , Alturki Rasha , Herzallah Nawal 
Published: December 2023

PurposeThis study aims to investigate the opportunities and challenges of adopting ChatGPT in medical research.MethodsA qualitative approach with focus groups is adopted in this study. A total of 62 participants including academic researchers from different streams in medicine and eHealth, participated in this study.ResultsA total of five themes with 16 sub-themes related to the opportunities; and a total of five themes with 12 sub-themes related to the challenges were identified. The major opportunities include improved data collection and analysis, improved communication and accessibility, and support for researchers in multiple streams of medical research. The major challenges identified were limitations of training data leading to bias, ethical issues, technical limitations, and limitations in data collection and analysis.ConclusionAlthough ChatGPT can be used as a potential tool in medical research, there is a need for further evidence to generalize its impact on the different research activities.
Comprehensive analysis of senescence-related genes and immune infiltration in intervertebral disc degeneration: a meta-data approach utilizing bulk and single-cell RNA sequencing data
Authors: Deng Ya-Jun , Wang Xin-Gang , Li Zhi , Wang Bo , Li Jie , Ma Jun , Xue Xiong , Tian Xin , Liu Quan-Cheng , Liu Jia-Yuan , Zhang Ying , Yuan Bin 
Published: December 2023

Objectives: This study aims to identify the key senescence genes and potential regulatory mechanisms that contribute to the etiology of intervertebral disc degeneration (IDD).Method: We analyzed GSE34095 and GSE70362 datasets, identifying key senescence-related differentially expressed genes (DEGs) in IDD using lasso regression. Risk scores classified patients into high- and low-risk groups. We compared pathways, functions, and immune infiltration between these groups. Diagnostic ability was assessed using ROC curves and a nomogram predicted IDD incidence. In single-cell dataset GSE165722, we evaluated expression of key senescence-related DEGs.Results: We identified 12 key senescence-related DEGs distinguishing high- and low-risk IDD patients. Enrichment analysis revealed cellular stress response, apoptotic signaling pathway, and protein kinase activation differences. Immune cell analysis showed elevated eosinophils in low-risk group and increased effector memory CD8 T, central memory CD4 T, myeloid-derived suppressor, natural killer, monocyte, Type 1 T helper, plasmacytoid dendritic, and natural killer T cells in high-risk group. A nomogram using AUC &gt;0.75 genes (CXCL8, MAP4K4, MINK1, and TNIK) predicted IDD incidence with good diagnostic power. High senescence scores were observed in neutrophils.Conclusion: Our diagnostic model, based on key senescence-related DEGs and immune cell infiltration, offers new insights into IDD pathogenesis and immunotherapy strategies.