bluuebunny/crossref_metadata_2025_split huggingface dataset:
Una propuesta para la enseñanza y el aprendizaje en prácticas clínicas de estudiantes de fisioterapia
Authors: Chávez-Ciau Irving David , López-Gamboa Galo Emanuel 
Published: January 2024

Introducción: El grado de fisioterapia se obtiene al cursar una preparación universitaria de 4 a 5 años con contenido teórico y práctico en su diseño curricular. En el segundo año de formación se realiza un periodo llamado “práctica clínica” donde, a través de la interacción con el paciente, el estudiante aprende y demuestra distintas habilidades clínicas; sin embargo, la enseñanza durante esta etapa puede descuidar competencias adicionales a la formación del alumno.
Objetivo: Diseñar una propuesta didáctica de enseñanza y aprendizaje para educadores clínicos mediante el diagnóstico de habilidades clínicas y humanas de formación identificadas en estudiantes de fisioterapia.
Método: Se realizó un estudio exploratorio y un muestreo no probabilístico por conveniencia a 2 grupos; el primer grupo formado por 32 estudiantes de la licenciatura en fisioterapia, superiores al sexto semestre, que realizaron prácticas clínicas en el área de terapia física del Hospital Regional ISSSTE “Elvia Carrillo Puerto”, durante el periodo comprendido de febrero 2019 a enero 2020; y el segundo grupo formado por 3 terapeutas adscritos de la institución, encargados de la formación clínica de los alumnos.
Resultados: De los 3 terapeutas adscritos al hospital, 1 refirió como “muy bueno” al proceso de enseñanza y aprendizaje durante las prácticas clínicas en fisioterapia; sin embargo, únicamente el 33.3% de los encuestados los aplica regularmente para la enseñanza y conclusión de habilidades en los estudiantes. El 43.8% de los alumnos encuestados categorizaron su enseñanza clínica como “bueno” durante su periodo de prácticas, siendo las habilidades clínicas las más frecuentemente practicadas y las habilidades intrapersonales las menos abordada para su aprendizaje.
Conclusiones: La propuesta de formación facilita la conclusión de mejores estándares de competencia en la formación de estudiantes en fisioterapia lo que garantiza a egresados capaces de afrontar las demandas de los pacientes, proporcionando un trato profesional y humano a sus futuros usuarios.
In-vivo Pharmacological Evaluation of Analgesic Activity of Ethanolic Extract of Doronicum hookeri Clarke Rhizomes in Wistar Rats
Authors: Wani Shubham , Gour Rekha , Patel Anant K. 
Published: January 2024

A number of plants are used traditionally in different medical conditions by practitioners of traditional medicines but their claim is not yet evaluated scientifically in laboratory animals. Based on the ethnomedical claims made by the Unani health practitioners, the Clarke rhizomes of Doronicum Hookeri was evaluated for analgesics activity in rats to confirm its claim. The successive plant extraction was carried out using Soxhlet apparatus by employing ethanol as a solvent of the dried rhizomes of Doronicum Hookeri. The % yield of extracted compound was 28.27% w/w. The qualitative preliminary phytochemical screening revealed the presence of alkaloids, saponins, tannins, flavonoids, glycosides, phenolic content, terpenoids and volatile oils in the rhizomes of ethanolic extract of D. Hookeri. The extract was orally administered in rats at low dose and high dose (200 mg/kg, 400 mg/kg) and was evaluated using Eddy’s Hot Plate Method in rats for analgesics activity. Diclofenac sodium (50 mg/kg) and was taken as a standard drug. The maximum possible analgesia % of ethanolic extract of rhizomes of D. Hookeri were found to be highest at a dose of 400mg/kg which showed 68.95% and 80% analgesia at 45 minute and 60 minute which when compared to Diclofenac sodium showed 73.28% and 85.71% at 45 minute and 60 minutes. The analgesic efficacy of ethanolic extract of rhizomes of D. Hookeri showed significant analgesic activity (p<0.04) in dose dependent manner at different time intervals of 0, 15, 30, 45 and 60 min. This asserts ethnomedical claims of some tribes regarding the analgesic activity of this plant.
Keywords - Analgesics, eddy’s hot plate, D. Hookeri, Diclofenac sodium.
Adult Onset Still’s Disease in a Patient with Fever of Unknown Origin: A Rare Case
Authors: Kumari Silky , Das Subhankar , Kumari Sudha , Ranjan Gyan , Barik Mahaprasad , Kanta Ramya Ranjan , Nishad Somnath 
Published: January 2024

Adult onset Still’s disease (AOSD) is a rare clinical entity with unknown etiology, characterized by arthritis, fever, evanescent rash, and other systemic presentations. AOSD generally does not overlap with other rheumatic diseases. AOSD is a diagnosis by exclusion, and it is one of the common causes of pyrexia of unknown origin (PUO) which can be life-threatening if mistreated. Although steroids are the first line of therapy, about 20%-30% of patients are refractory, intolerant, and or relapse during tapering or upon discontinuation of steroids. There are no clinical guidelines in treating such patients, which is challenging.
Keywords: Still’s disease, arthritis, fever, auto-inflammatory
Experimental animal models for gastric ulcer / peptic ulcer: An overview
Authors: Satapathy Trilochan , Sen Kalpana , Sahu Shailesh , Pradhan Bharti , Gupta Ayushi , Khan Md. Altaf , Kumar Dheeraj , Satapathy Abinash , Yadav Neha 
Published: January 2024

In the present study we have discussed around sixteen different animal models used worldwide for the scientific research and new drug discovery. The main aim of the using experimental animal models in drug discovery is to establish and provide evidence for non-clinical 'proof-of-concept' for the safety, efficacy, and target of interest for specific drug molecules. Experimental preparations developed in one species for the purpose of studying phenomena occurring in another species. The use of experimental animal models serves to better understand the origins, pathology, and the overall nature of comparable diseases of humans being. Similarly, animal models perform duties for in the development of safe and effective treatments and cures of such diseases and/or associated symptoms. Experimental animal models for drug discovery and development have played a major role in the characterization of the pathophysiology of diseases and associated mechanisms of injury, drug target identification, and evaluation of novel therapeutic agents for toxicity, pharmacokinetics and pharmacodynamics activity. Through animal model researchers can perform experiments that would be impractical or ethically prohibited with humans. There are various animal models used for screening of uncountable therapeutic activities, in this review our main focus is animal models used for peptic ulcer. Peptic ulcer is one of the worldwide diseases where 10% of adults are affected by peptic ulcer once in their lifetime. The antiulcer models for drug development against gastric and duodenal ulcer studies are limited in number that has hindered the progress of targeted therapy in this field. Therefore, it is necessary to review the literature on experimental animal models that are used to screen agents with potential anti-gastric ulcer activity and describe their biochemical basis in order to facilitate their use in the development of new preventive and curative antiulcer drugs. There are many models used to induce ulcer such as pylorus ligation or it can be chemically induced by ethanol, NSAIDs (e.g. indomethacin) or many more. In this review paper, current in-vivo animal models of ulcers and the pathophysiological mechanisms underlying their induction, their drawbacks, as well as the challenges associated with their use have been discussed.
Gels Containing Poloxamer 407 and Sodium Alginate as Vehicles for Vaginal Administration
Authors: N’GUESSAN-GNAMAN Kakwokpo Clémence , TUO-KOUASSI Awa Nakognon , AKA-ANY-GRAH Sandrine , CHOUGOUO KENGNE-NKUITCHOU Rosine Désirée , ANIN Apo Laurette , LIA Arthur José , N’GUESSAN Alain , DALLY Ismael 
Published: January 2024

Sodium alginate and poloxamer 407 were both studied in order to design a hydrogel-based delivery system as a platform for the formulation of vaginal medecines. Sodium alginate is a natural anionic mucoadhesive polymer while poloxamer 407 is a temperature-sensitive polymer. A commercial alginate was characterized. Then, its solutions (0.5-2 % w/w), poloxamer 407 solutions (16-21.5 % w/w) and their mixtures were prepared. Their rheological properties and the influence of vaginal simulated fluid were assessed. This commercial alginate had a mannuronate-to-guluronate ratio of 1.24, a weight-average molecular weight of 300 000 ± 2% g.mol-1, a polydispersity index of 1.8 ± 3%. Alginate solutions displayed a viscous behavior not suitable for a vaginal administration. Poloxamer solutions and their mixtures with alginate were temperature-sensitive, shear-thinning, non-thixotropic and had an elastic behavior suitable for a vaginal administration. Their resistance to dilution with vaginal fluid could prolonge vaginal residence.
Keywords: Formulation, poloxamer 407, rheology, sodium alginate, temperature–sensitive, vaginal fluid, viscoelastic properties.
Solubility enhancement of meloxicam by phospholipid complexation
Authors: Bhadange Vaibhav , Kawtikwar Pravin , Jogdand Supriya , Kawtikwar Ankita 
Published: January 2024

The best solubility enhancement approach is phospholipids complexation. It has been effectively employed by a number of writers to enhance the permeability, oral bioavailability, and solubility of several medicinal substances. The meloxicam is a member of BCS Class II, and because of its poor solubility and high permeability, its clinical application may have been constrained. Therefore, it is necessary to use a method that modifies the biopharmaceutical features. In this work, meloxicam, an NSAID with demonstrated anticancer action, was combined with phospholipid to increase its solubility. Utilizing solvent evaporation, the meloxicam phospholipid complex was produced. Particle size, zeta potential, SEM analysis, in vitro drug release, and solubility were assessed for the produced complex. The results obtained in this study showed the smaller particle size in nanometer range and physical stability with desired zeta potential. Meloxicam's prolonged release from the phospholipid complex is demonstrated by the in vitro drug release investigation. The apparent solubility analysis of meloxicam phospholipid complex. Pure meloxicam showed that the drug's solubility was several times higher than that of the pure form. Hence in conclusion we can say that the phospholipid complexation could be the ideal method for solubility enhancement of drug like meloxicam.
Keyword: Meloxicam, phospholipid complex, solubility, drug release
Rola Agencji Nieruchomości Rolnych w powiększaniu i tworzeniu gospodarstw rolnych
Authors: Nawrocki Tomasz , Podgórski Bogdan 
Published: January 2024

W pracy podjęto próbę oceny roli ANR w powiększaniu i tworzeniu gospodarstw rolnych. Analizę przeprowadzono w oparciu o informacje pochodzące z raport ów z działalności Agencji, opracowań wewnętrznych i dostępnej literatury. Zaprezentowane wyniki świadczą o znacznym wkładzie ANR w kształtowanie struktury agrarnej, szczególnie tam, gdzie występowała koncentracja gruntów przejętych do Zasobu WRSP.
Uwarunkowania logistyczno-organizacyjne i technologiczne budowy produkcyjno-dystrybucyjnych sieci dla produktów ekologicznych
Authors: Drelichowski Ludosław 
Published: January 2024

Poszukiwanie nisz rynkowych na globalnym rynku jest zadaniem niezwykle trudnym, bowiem cel ten stawia sobie równocześnie wielu producentów żywności i firm agrobiznesu. Nisze rynkowe produktów ekologicznych poddane są wielu uwarunkowaniom związanym z szybkim okresem utraty szczególnych walorów jakościowych, zwłaszcza gdy oferta dotyczy produktów ekologicznych. Rozdrobnienie polskich gospodarstw rolnych i występujące warunki klimatyczne powodują, że w dużej skali może być realizowana produkcja i dystrybucja jaj klasy „0”, które mogą stanowić ofertę polskiego produktu ekologicznego determinowanego maksymalną koncentracją kur do 200 niosek/ha. Uznawana dotychczas za słabość systemową duża liczba drobnych gospodarstw pozwala oczekiwać, że zorganizowanie sieci koordynowanych przez integratorów baz logistycznych producentów jaj ekologicznych (80 000-120 000 gospodarstw) może decydować o występującej w polskich warunkach przewadze konkurencyjnej.
Elastyczność produkcyjna i dochodowa procesu produkcji w towarowych gospodarstwach rolnych
Authors: Niezgoda Dionizy 
Published: January 2024

Wykorzystując funkcję Cobba-Duglasa, oszacowano elastyczność produkcji i dochodu względem zagregowanych czynników produkcji, tj. ziemi, pracy i kapitału, w towarowych gospodarstwach rolnych dla danych liczbowych zebranych w 2004 i 2007 roku dla potrzeb Polskiego FADN. W obu badanych latach wystąpiły korzyści skali. Produkcja (SE131) wywołana wzrostem o 1% nakładów badanych czynników, tj. ziemi (SE025), pracy (SE011) i kosztów ogółem (SE270), zwiększyła się w 2004 roku o 1,0845% a w 2007 roku o 1,0713%. Z kolei elastyczność dochodowa wyniosła 1,2246% w roku 2004 i 1,1363% w roku 2007 gdy nakłady czynników SE025, SE011 i SE270 zwiększono o 1 pp. Głównym czynnikiem określającym elastyczność produkcji i dochodu były koszty ogółem (SE270).
Wyniki ekonomiczne wybranych polskich gospodarstw mlecznych w latach 2006-2009
Authors: Wójcik Agata 
Published: January 2024

W artykule przedstawiono kształtowanie się cen mleka, całkowitych kosztów produkcji mleka, kosztów bezpośrednich, kosztów pracy i ziemi, kosztów budynków, kosztów kwoty mlecznej oraz pozostałych kosztów w wybranych gospodarstwach polskich. Najważniejszym źródłem przychodów w analizowanych gospodarstwach były przychody ze sprzedaży mleka. Dodatkowym źródłem przychodów była sprzedaż bydła, a także płatności bezpośrednie oraz pozostałe przychody. Artykuł dostarcza także informacji o dochodowości oraz progach rentowności badanych gospodarstw. Do przeprowadzenia badania wykorzystano dane z wybranych gospodarstw polskich specjalizujących się w produkcji mleka zebrane dla Europejskiego Stowarzyszenia Producentów Mleka (European Dairy Farmers) w latach 2006-2009.
Austeridade e pandemia: perspectivas para as cidades brasileiras
Authors: Depieri Marcelo Álvares de Lima , Ramos André Paiva 
Published: January 2024

A partir de uma análise do desempenho da economia brasileira entre 2015 e 2019 e das principais medidas e reformas implementadas nesse período, o artigo aborda a situação do emprego e da renda na cidade de São Paulo diante da crise econômica da Covid-19 e aponta perspectivas para as cidades brasileiras. Foram coletadas informações em base de dados, trabalhos, relatórios, a partir de documentos abertos ao público, e notícias de jornais sobre a situação do emprego, da renda e das políticas de governo. A primeira seção analisa o desempenho da economia brasileira de 2015 a 2020 no contexto da agenda de austeridade fiscal, manifestada na Emenda Constitucional 95, na Reforma Trabalhista e na Reforma da Previdência, e da crise oriunda da pandemia da Covid-19. A segunda seção examina os impactos da crise da Covid-19 no mercado de trabalho na cidade de São Paulo, e apresenta aspectos relativos ao custo de vida na cidade. A terceira e última seção trata das perspectivas para as cidades brasileiras por meio da análise de algumas medidas em curso que afetam diretamente a vida dos que vivem nas cidades, tais como: a Medida Provisória 996, que institui o Programa Casa Verde Amarela, o novo marco legal do saneamento e o Decreto nº 10.530 de 26 de outubro de 2020, que traz alterações na área da saúde.
“To find God in all things”: the meeting of faith and mathematics in Jesuit education during the scientific revolution
Authors: Araújo Daniel Ferreira 
Published: January 2024

ResumoÉ bem conhecido e aceito que o início da tradição matemática dos jesuítas se deve a Christopher Clavius, professor de Matemática no Colégio Romano entre 1567 e 1595. Neste artigo, questiona-se: Quais eram os aspectos sociais, políticos, filosóficos, e as razões religiosas que levaram Clavius a criar um currículo educacional inovador que incluiu o ensino de matemática nas faculdades jesuítas? Para responder à esta pergunta, olhamos para os primeiros anos da Companhia de Jesus considerando o contexto histórico e uma análise de como o aprendizado matemático interagiu com a doutrina Católica.Palavras-chave: Pedagogia Jesuítica; Ciência e Fé; Igreja e ciência AbstractIt is well known and accepted that the beginning of the mathematical tradition of the Jesuits is due to Christopher Clavius, professor of Mathematics in the Roman College between 1567 and 1595. In this article, the question is: What were the social, political, philosophical, and religious reasons that lead Clavius to create an innovative educational curriculum that included the teaching of mathematics in the Jesuit colleges? To answer this question, we look at the early years of the Society of Jesus considering the historical context and an analysis of how mathematic learning interacted with the Catholic doctrine.Keywords: Jesuit pedagogy; science and faith; Church and science
Ensino de Estequiometria Catalisado pela História e Filosofia das Ciências.
Authors: Ribeiro Marcos Vinicius , Fonseca Marina Assis 
Published: January 2024

Resumo
Neste trabalho relata-se um projeto de intervenção no ensino de estequiometria para graduandos em Engenharia. O fraco desempenho dos alunos na aprendizagem deste conteúdo é um aspecto recorrente na prática docente de um dos autores. Uma sequência didática baseada em história e filosofia da ciência foi elaborada e aplicada durante a disciplina de Química Geral no 1º semestre de 2019. A visão prévia de ciências dos alunos foi aferida através do questionário VOSTS e entrevistas semiestruturadas aplicadas após a finalização do projeto de ensino. Os resultados indicaram previamente uma visão rígida da ciência para 42% dos alunos; um avanço em todos os indicadores de desempenho mensurados nas questões de estequiometria da avaliação final e, por fim, sugerem uma mudança de compreensão dos alunos sobre a natureza da ciência. O uso da história e filosofia da ciência favoreceu o engajamento e despertou o interesse dos alunos permitindo uma aprendizagem significativa da estequiometria.
Palavras-chave: Estequiometria, Graduação, História e Filosofia da Ciência.
Abstract
This paper reports an intervention project in the teaching of stoichiometry for undergraduates in engineering. The poor performance of students in learning this content is a recurring aspect in the teaching practice of one of the authors. A didactic sequence based on the history and philosophy of science was elaborated and applied during the General Chemistry course in the first semester of 2019. The students' previous view of sciences was assessed through the VOSTS questionnaire and semi-structured interviews applied after the end of the teaching project. The results previously indicated a rigid view of science for 42% of students; a breakthrough in all performance indicators measured in the final assessment questions of stoichiometry and ultimately suggest a change in students' understanding of the nature of science. The use of the history and philosophy of science favored the engagement and aroused the interest of the students allowing a meaningful learning of stoichiometry.
Keywords: Stoichiometry, Graduation, History and Philosophy of Science.
As organizações didáticas e matemáticas nos livros didáticos de matemática utilizados na escola básica brasileira<br>Las organizaciones didácticas y matemáticas en los libros didácticos de matemáticas utilizados en la escuela básica brasileña
Authors: Coutinho Cileda de Queiroz e Silva , Goulart Amari 
Published: January 2024

Este artigo tem por objetivo analisar quais são as organizações matemáticas e didáticas presentes nos livros didáticos utilizados nas escolas públicas brasileiras. Para atingirmos tal objetivo, analisamos duas coleções de livros didáticos, uma voltada para os quatro últimos anos do Ensino Fundamental e a outra para o Ensino Médio, ambas aprovadas pelo Programa Nacional do Livro Didático. Cada uma das coleções foi analisada à luz da Teoria Antropológica do Didático e, de acordo com as análises realizadas, encontramos Organizações Matemáticas limitadas a um saber fazer cuja razão de ser não é mais significativa na Instituição Escola. Tal fato pode ser observado analisando-se os Tipos de Tarefa e as técnicas presentes ao longo do capítulo destinado à Probabilidade. Quanto às organizações didáticas, observamos uma tendência tecnicista, ou seja, Tipos de Tarefa que demando apenas um enfoque procedimental, sem apelo à mobilização dos conceitos para a resolução do exercício. This article aims to analyse the mathematical and didactic organisations present in the textbooks used in Brazilian public schools. For this, we examined two textbook collections, one for middle school and the other for high school, both approved by the National Textbook Programme. Each of the collections was analysed in the light of the anthropological theory of the didactic. The study unveiled mathematical organisations limited to a know-how whose raison d'être is no longer valuable in the school institution. This fact can be observed through the analysis of the types of task and the techniques found throughout the chapter aimed at probability. As for the didactic organisations, we observed a technicist tendency, i.e., types of task that demanded only a procedural focus, without requiring the mobilisation of concepts to solve the exercise. Este artículo tiene como objetivo analizar las organizaciones matemáticas y didácticas presentes en los libros didácticos utilizados en las escuelas públicas brasileñas. Para ello, examinamos dos colecciones de libros didácticos, una para el liceo y la otra para bachillerato, ambas aprobadas por el Programa Nacional de Libros Didácticos Se analizó cada una de las colecciones a la luz de la teoría antropológica de lo didáctico. El estudio reveló organizaciones matemáticas limitadas a un saber hacer cuya raison d'être ya no se valora en la institución escolar. Este hecho se puede observar mediante el análisis de los tipos de tarea y las técnicas encontradas a lo largo del capítulo orientado a la probabilidad. En cuanto a las organizaciones didácticas, observamos una tendencia tecnicista, es decir, tipos de tarea que demandaban solo un enfoque procedimental, sin requerir la movilización de conceptos para resolver el ejercicio.
The Influence of Rubberwood Biochar Size on the Effectiveness of Using Urea Fertilizer in the Cultivation of Pakcoy (Brassica chinensis L.)
Authors: Haryanto Agus , Mudita Nyoman Arif , Waluyo Sri , Triyono Sugeng 
Published: January 2024

The effectiveness of fertilizer and crop production can be increased through the provision of biochar as a soil amendment. This research aims to evaluate the effect of the combination of varying sizes of rubber wood biochar with doses of urea fertilizer on the growth of pak choy mustard plants. The research was conducted with two factors arranged in a completely randomized design. The first factor is the size of the rubber wood biochar and the second factor is the dose of Urea fertilizer, each consisting of 4 levels. All treatment combinations were carried out with 3 repetitions. The response variables observed include soil pH, plant height, number of leaves, canopy area, and fresh plant production. The results showed biochar size factor had a significant effect on soil pH and fresh weight. The urea fertilizer dosage factor shows a significant influence on the plant height and fresh weight. The treatment with the most optimal growth was 1 mm biochar produced yield of 19.03 g/plant, while Urea dose of 2 g/plant produced pak choy plants of 20.72 g/plant. Keywords: Biochar, Pakchoy, rubberwood, size, Urea.