bluuebunny/crossref_metadata_2025_split huggingface dataset:
Constraints in Organizations of Agricultural Knowledge Creation, Information Management and Technology Delivery System in Bundelkhand Region of Uttar Pradesh, India
Authors: Managuli Gangubai Shivappa , Sharma J. P. , Gills Reshma , Burman R. R. , Gurung Bishal 
Published: November 2023

The present study was conducted to delineate the various constraints faced by the institutions doing agricultural knowledge, information management, and technology delivery. The Bundelkhand Region of U.P. was purposively chosen for this study because of the presence of major institutes such as the Indian Grassland and Fodder Research Institute (IGFRI), Central Agroforestry Research Institute and agricultural universities located in Banda and Jhansi, ICAR KVKs, state government line departments, ATMA and many related NGOs. Secondary data were collected through the study of extant literature. Identified major constraints were sorted out with the help of experts. Primary data was collected from officials of every organization through direct personal interviews and focussed group discussions. The total sample size was 50. The constraints were grouped into three categories; that is, constraints in knowledge creation, information management, and technology delivery. Rank Based Quotient (RBQ) method was used to quantify the responses, in order to establish the major constraints with severe effects. Findings revealed there is a need for knowledge experts to periodically train the work-force of the sampled organizations to update the skill of the scientists. Such up scaling of employees’ knowledge would increase digitalization, improve effective management of information; enhance coordination among different organizations while reducing duplicative efforts or misplaced efforts.
CFD‐based bioreactor model with proportional–integral–derivative controller functionality for dissolved oxygen and pH
Authors: Oliveira Christopher L. , Pace Zoe , Thomas John A. , DeVincentis Brian , Sirasitthichoke Chadakarn , Egan Susan , Lee Jongchan 
Published: November 2023

AbstractA physics‐based model for predicting cell culture fluid properties inside a stirred tank bioreactor with embedded PID controller logic is presented. The model evokes a time‐accurate solution to the fluid velocity field and overall volumetric mass transfer coefficient, as well as the ongoing effects of interfacial mass transfer, species mixing, and aqueous chemical reactions. The modeled system also includes a direct coupling between process variables and system control variables via embedded controller logic. Satisfactory agreement is realized between the model prediction and measured bioreactor data in terms of the steady‐state operating conditions and the response to setpoint changes. Simulation runtimes are suitable for industrial research and design timescales.
Sustainability leadership: An integrative review and conceptual synthesis
Authors: Sajjad Aymen , Eweje Gabriel , Raziq Muhammad Mustafa 
Published: November 2023

AbstractOver the past few decades, scholars have extensively investigated the topic of leadership, contributing to the development of diverse leadership theories and contemporary managerial practice. However, the emergence and renewed focus on societal grand challenges warrant an alternative approach to leadership such as sustainability leadership. Despite the critical importance of sustainability leadership in addressing these global concerns, scholarly research in this field of inquiry, by and large, remained scant and fragmented, lacking conceptual coherence and theoretical integration. While the existing literature provides insights into sustainability leadership characteristics, competencies, behaviors, and actions, it failed to integrate a holistic understanding of how these aspects are connected and affect each other. Accordingly, the purpose of this review paper is to provide conceptual synthesis and critical appraisal of the extant literature on sustainability leadership. Drawing on a systems theory perspective on paradox, we developed an integrative multilevel sustainability leadership framework, which demonstrates the linkages between individual‐level mechanisms (micro), organizational‐level mechanisms (meso), and societal context (macro). The framework explicates the key underlying mechanisms of sustainability leadership functioning embedded in paradoxical tensions to address complex and multifaceted sustainability issues. The paper concludes by offering implications for research and managerial practice and avenues for future research.
Chronic administration of delta9‐tetrahydrocannabinol protects hyperinsulinemic gastric tissue in rats
Authors: Colak Dilara Kamer , Coskun Yazici Zeynep Mine , Bolkent Sema 
Published: November 2023

AbstractHyperinsulinemia (HI) can result from some reasons such as an increase in basal/fasting circulating insulin and/or potentiation of postprandial insulin production. Diabetes mellitus (DM) is indirectly related to HI since it both causes and results from insulin resistance. Understanding the causes of HI and treating this is crucial for preventing DM. Previous research has shown that delta9‐tetrahydrocannabinol (THC) has medicinal benefits. In light of this, the relationship between THC and oxidative stress, DNA repair mechanism, apoptosis, and its regulatory impact on appetite hormones in the gastric tissue of hyperinsulinemic rats has been investigated for the first time. Male rats (Spraque−Dawley, total = 32) were used, and they were randomly divided into the following groups (n = 8 in each group): control (CTRL), HI, THC administered control (THC, 1.5 mg/kg/day, during 4 weeks), and THC administered HI (HI + THC) groups. The number of poly (ADP‐ribose) polymerase‐1 and proliferating cell nuclear antigen (PCNA) and caspase‐3 immunopositive cells in the HI group was significantly reduced compared to the CTRL group. The number of PCNA and caspase‐9 immunopositive cells was significantly increased in the HI + THC group compared to the HI group. Obestatin immunopositive cell numbers in the HI + THC group were higher than in the HI and CTRL groups. The results show that THC administration may affect the regulation of appetite hormones and regeneration in the fundus of rats with HI. Glutathione (GSH) levels were higher in the HI + THC group than in the HI group. Both immunohistochemical and biochemical analyses revealed that THC promotes regeneration and regulates appetite hormones in hyperinsulinemic gastric tissues.
Habitat‐specific impacts of climate change on the trophic demand of a marine predator
Authors: Luongo Sarah M. , Schneider Eric V. C. , Harborne Alastair R. , Kessel Steven T. , Papastamatiou Yannis P. 
Published: November 2023

AbstractMetabolic ecology predicts that ectotherm metabolic rates, and thus consumption rates, will increase with body size and temperature. Predicted climatic increases in temperature are likely to increase the consumption rates of ectothermic predators; however, the ecological impact of these increases will partly depend on whether prey productivity changes with temperature at a similar rate. Furthermore, total predator consumption and prey productivity will depend on species abundances that vary across habitat types. Here we combine energetics and biotelemetry to measure consumption rates in a critically endangered coral reef predator, the Nassau grouper (Epinephelus striatus), in The Bahamas. We estimate that, at present, the Nassau grouper needs to consume 2.2% ± 1.0% body weight day−1, but this could increase up to 24% with a predicted 3.1°C increase in ocean temperature by the end of the century. We then used surveys of prey communities in two major reef habitat types (Orbicella reef and Gorgonian plain), to predict the proportion of prey productivity consumed by grouper and how this varied by habitat with changing climates. We found that at present, the predicted proportion of prey productivity consumed by Nassau grouper decreased with increasing prey productivity and averaged 1.2% across all habitats, with a greater proportion of prey productivity consumed (maximum of 5%) in Gorgonian plain habitats. However, because temperature increases consumption rates faster than prey productivity, the proportion of prey productivity consumed in a Gorgonian plain habitat could increase up to 24% under future climate change scenarios. Our results suggest that increasing ocean temperatures will lead to significant energetic challenges for the Nassau grouper because of differential impacts within reef food webs, but the magnitude of these impacts will probably vary across prey productivity gradients.
Clinical predictors of right ventricular dysfunction and association with adverse outcomes in peripartum cardiomyopathy
Authors: Imran Tasnim F. , Ataklte Feven , Khalid Mahnoor , Lopez Diana , Mohebali Donya , Bello Natalie A. , Gaziano J. Michael , Djousse Luc , Arany Zolt , Sabe Marwa A. , French Katharine , Poppas Athena , Wu Wen‐Chih , Choudhary Gaurav 
Published: November 2023

AbstractAimsWe sought to identify factors associated with right ventricular (RV) dysfunction and elevated pulmonary artery systolic pressure (PASP) and association with adverse outcomes in peripartum cardiomyopathy (PPCM).Methods and resultsWe conducted a multi‐centre cohort study to identify subjects with PPCM with the following criteria: left ventricular ejection fraction (LVEF) < 40%, development of heart failure within the last month of pregnancy or 5 months of delivery, and no other identifiable cause of heart failure with reduced ejection fraction. Outcomes included a composite of (i) major adverse events (need for extracorporeal membrane oxygenation, ventricular assist device, orthotopic heart transplantation, or death) or (ii) recurrent heart failure hospitalization. RV function was obtained from echocardiogram reports. In total, 229 women (1993–2017) met criteria for PPCM. Mean age was 32.4 ± 6.8 years, 28% were of African descent, 50 (22%) had RV dysfunction, and 38 (17%) had PASP ≥ 30 mmHg. After a median follow‐up of 3.4 years (interquartile range 1.0–8.8), 58 (25%) experienced the composite outcome of adverse events. African descent, family history of cardiomyopathy, LVEF, and PASP were significant predictors of RV dysfunction. Using Cox proportional hazards models, we found that women with RV dysfunction were three times more likely to experience the adverse composite outcome: hazard ratio 3.21 (95% confidence interval: 1.11–9.28), P = 0.03, in a multivariable model adjusting for age, race, body mass index, preeclampsia, hypertension, diabetes, kidney disease, and LVEF. Women with PASP ≥ 30 mmHg had a lower probability of survival free from adverse events (log‐rank P = 0.04).ConclusionsAfrican descent and family history of cardiomyopathy were significant predictors of RV dysfunction. RV dysfunction and elevated PASP were significantly associated with a composite of major adverse cardiac events. This at‐risk group may prompt closer monitoring or early referral for advanced therapies.
Geographic variability in headward erosion of marsh tidal creeks: Ecological and physical causes
Authors: Hughes Zoe J. , Farron Sarah J. , FitzGerald Duncan M. 
Published: November 2023

AbstractExpansion of drainage networks through the headward erosion of tidal creeks is an eco‐geomorphologic response of salt marshes to accelerated sea‐level rise (SLR). This response can counter the negative impacts of an elevation deficit by increasing drainage and encouraging plant health, thereby reducing potential for submergence and marsh platform loss. In the wetlands of Cape Romain, SC, intense bioturbation near creek heads by the common marsh crab Sesarma reticulatum has been found to facilitate sediment erosion and rapid creek growth. This keystone grazer has been recently observed to have increasing influence on landscape evolution throughout the southeast US coast. Here, we compare measurements taken at Sapelo Island, GA, with those previously collected at Cape Romain, to confirm that eco‐geomorphic feedbacks facilitating creek growth at each location are similar, and to compare these processes under differing background conditions. We use sediment cores, precise elevation measurements and historical imagery to compare substrate properties, elevation within the tidal frame, creek growth rates and drainage morphology at both sites. Our results show identical processes; however, the higher elevation of the marsh at Sapelo Island leads to shallower and shorter periods of tidal inundation, explaining the greater soil strength and lower belowground biomass compared with the marsh at Cape Romain. The smaller tidal range at the site in Cape Romain compared with Sapelo Island translates to a proportionally shallower depth of tidal creeks, which therefore requires less erosion to produce headward creek extension. These effects are likely to have contributed to slower growth rates of tidal creeks at Sapelo Island during the past several decades of SLR. Our findings highlight the similarities in process but differences in rates in how marshes are responding to climate‐related stress.
A case of pancreatic adenosquamous carcinoma with direct invasion to the gastrointestinal tract through the retention cyst wall: A rare case report
Authors: Hamada Takuro , Yamaguchi Atsushi , Kato Naohiro , Sugata Syuhei , Furuya Nao , Tamaru Yuzuru , Kusunoki Ryusaku , Kuwai Toshio , Kouno Hirotaka , Kohno Hiroshi , Sudo Takeshi , Kuraoka Kazuya , Oka Shiro 
Published: November 2023

AbstractA 62‐year‐old man presented with a 7‐cm cystic lesion with irregularly thickened cyst wall in contact with the pancreatic tail. The pancreatic tail was described as hypoechoic on endoscopic ultrasonography. The cyst subsequently increased rapidly to 13 cm, and surgery was performed. This revealed adenosquamous carcinoma in the pancreatic tail to have invaded the stomach and transverse colon along the cyst wall. The cyst was diagnosed as a retention cyst due to pancreatic tail tumor. Invasion of nearby organs by a pancreatic cancer via the retention cyst wall is very rare, but it is necessary to keep the potential for such progress in mind.
Strategic organizational changes: Adopting data‐driven decisions
Authors: Bilkštytė‐Skanė Daina , Akstinaite Vita 
Published: November 2023

AbstractThe paper examines the adoption of a data‐driven decision‐making (DDDM) process in organizations from purposefully selected European Union (EU) countries. It determines what organizational changes are required to adopt this process in organizations. This study uses a mixed‐method approach to identify organizational changes required for DDDM adoption. The responses from quantitative research in 10 EU countries (1091 respondents) and qualitative research with 20 C‐level managers are analyzed. The study offers the following organizational changes needed to implement DDDM in organizations: culture and mindset changes, digitalization, process improvements, new competencies, re‐organization, and legal requirements. This research contributes to a better understanding of the usage and adoption of DDDM globally and suggests specific organizational changes required to adopt this process.
What's new in thoracic oncology
Authors: Pezeshkian Fatemehsadat , McAllister Miles , Singh Anupama , Theeuwen Hailey , Abdallat Mohammad , Figueroa Paula Ugalde , Gill Ritu R. , Kim Anthony W. , Jaklitsch Michael T. 
Published: November 2023

AbstractMany changes have occurred in the field of thoracic surgery over the last several years. In this review, we will discuss new diagnostic techniques for lung cancer, innovations in surgery, and major updates on latest treatment options including immunotherapy. All these have significantly started to change our approach toward the management of lung cancer and have great potential to improve the lives of our patients afflicted with this disease.
Dielectric Analysis of Blended Polysulfone/Polyethylenimine Membrane Contactors for CO2 Capture
Authors: Pascual‐José Borja , Zare Alireza , Giamberini Marta , Reina José Antonio , Ribes‐Greus Amparo 
Published: November 2023

AbstractPolysulfone membranes, used as contactors for CO2 capture, are blended with two different hyperbranched polyethyleneimines modified with benzoyl chloride (Additive 1) and phenyl isocyanate (Additive 2) in different percentages. Fourier‐transformed infrared spectra evidence the presence of urea and amide groups, whereas the field emission scanning electron microscopy images show differences in the microstructure of the blended membranes. Dielectric spectra determine the motions of the side and backbone chains, which can facilitate the diffusion of CO2. The spectra consist of six dielectric processes; three of them are due to the polysulfone (γPSf, βPSf, and αPSf), whereas the rest are characteristic of the additive (γHPEI, βHPEI, and αHPEI). The benzoyl chloride and phenyl isocyanate functional groups introduce variations in molecular mobility and modify the relaxations associated with the hyperbranched polyethyleneimine (HPEI). The additives also increase the conductivity of the blended membranes, which can compromise the performance of the membranes, specifically in the case of Additive 1. Ion hopping is found to be the prevailing charge transport mechanism while both relaxations, αHPEI and αPSf, are actives. These results, together with the final morphology of the membranes, may explain the greater absorption capacity of the membranes prepared with the hyperbranched polyethyleneimine modified with Additive 2.
Parkinson's Disease and Driving Fitness: A Systematic Review of the Existing Guidelines
Authors: Stamatelos Petros , Economou Alexandra , Yannis George , Stefanis Leonidas , Papageorgiou Sokratis G. 
Published: November 2023

AbstractBackgroundMotor/nonmotor symptomatology and antiparkinsonian drugs deteriorate the driving ability of Parkinson's disease (PD) patients.ObjectivesTreating neurologists are frequently asked to evaluate driving fitness of their patients and provide evidence‐based consultation. Although several guidelines have been published, the exact procedure along with the neurologist's role in this procedure remains obscure.MethodsWe systematically reviewed the existing guidelines, regarding driving fitness evaluation of PD patients. We searched MEDLINE and Google Scholar and identified 109 articles. After specified inclusion criteria were applied, 15 articles were included (nine national guidelines, five recommendation papers, and one consensus statement).ResultsThe treating physician is proposed as the initial evaluator in 8 of 15 articles (neurologist in 2 articles) and may refer patients for a second‐line evaluation. The evaluation should include motor, cognitive, and visual assessment (proposed in 15, 13, and 8 articles, respectively). Specific motor tests are proposed in eight articles (cutoff values in four), whereas specific neuropsychological and visual tests are proposed in seven articles each (cutoff values in four and three articles, respectively). Conditional licenses are proposed in 11 of 15 articles, to facilitate driving for PD patients. We summarized our findings on a graphic of the procedure for driving fitness evaluation of PD patients.ConclusionsNeurological aspects of driving fitness evaluation of PD patients are recognized in most of the guidelines. Motor, neuropsychological, visual, and sleep assessment and medication review are key components. Clear‐cut instructions regarding motor, neuropsychological, and visual tests and relative cutoff values are lacking. Conditional licenses and periodical reevaluation of driving fitness are important safety measures.
Kristalle züchten: zwischen Alchemie und Wissenschaft
Authors: Müßler Marius , Pannwitz Andrea , Sorsche Dieter 
Published: November 2023

Abstract„Nur während der ruhigen Zeit zwischen den Jahren, wenn niemand im Labor ist, können die Kristalle schön wachsen“, heißt es, oder „Bestimmte Kristalle wachsen nur im Winter im dunklen, kalten Kühlschrank“. Manche verlassen sich auf Fliegenbeine als Kristallisationskeime oder stellen Kristallansätze offen auf die Fensterbank. Tipps und Tricks, um Kristalle herzustellen.
Analysentechnik: Schneller zu HPLC‐Methoden
Authors: Kuhlmann Christopher 
Published: November 2023

AbstractIntegrierte Softwareprogramme vereinfachen die Methodenentwicklung. So kann weniger erfahrenes Personal in kurzer Zeit die richtige Methode wählen – etwa wenn ein Oligonukleotid von seinen Nebenprodukten getrennt und analysiert werden soll.
Interview "Endverbraucher haben kritisch nachgefragt"
Authors: Neubauer Uta 
Published: November 2023

AbstractDas vorgeschlagene EU‐Verbot aller per‐ und polyfluorierten Alkylsubstanzen betrifft auch die Outdoor‐Branche, denn diese Stoffe werden in atmungsaktiven Membranen und wasserabweisenden Textilbeschichtungen eingesetzt. Wie das ohne diese Substanzen funktioniert, erläutert Bettina Roth, Leiterin des Qualitätsmanagements beim Outdoor‐Ausrüster Vaude im baden‐württembergischen Tettnang.
Entschlüsselte Wahrheiten: Wie entsteht der Stein der Weisen?
Authors: Hollweg Jürgen 
Published: November 2023

AbstractAus Mittelalter und Früher Neuzeit sind Schriften mit prachtvollen Illustrationen erhalten. Eine der bekanntesten ist „Splendor Solis“ über die Herstellung des Steins der Weisen.
Antibiotic use, best practice statement adherence, and UTI rate for intradetrusor onabotulinumtoxin‐A injection for overactive bladder: A multi‐institutional collaboration from the SUFU Research Network (SURN)
Authors: Shapiro Katherine , Anger Jennifer , Cameron Anne P. , Chung Doreen , Daignault‐Newton Stephanie , Ippolito Giulia M. , Lee Una , Mourtzinos Arthur , Padmanabhan Priya , Smith Ariana L. , Suskind Anne M. , Tenggardjaja Christopher , Van Til Monica , Brucker Benjamin M. 
Published: November 2023

AbstractIntroductionOnabotulinumtoxin A (BTX‐A) is a well‐established treatment for overactive bladder (OAB). The American Urological Association (AUA) 2008 Antibiotic Best Practice Statement (BPS) recommended trimethoprim‐sulfamethoxazole or fluoroquinolone for cystoscopy with manipulation. The aim of the study was to evaluate concordance with antibiotic best practices at the time of BTX‐A injection and urinary tract infection (UTI) rates based on antibiotic regimen.MethodsMen and women undergoing first‐time BTX‐A injection for idiopathic OAB with 100 units in 2016, within the SUFU Research Network (SURN) multi‐institutional retrospective database were included. Patients on suppressive antibiotics were excluded. The primary outcome was concordance of periprocedural antibiotic use with the AUA 2008 BPS antimicrobials of choice for “cystoscopy with manipulation.” As a secondary outcome we compared the incidence of UTI among women within 30 days after BTX‐A administration. Each outcome was further stratified by procedure setting (office vs. operating room; OR).ResultsOf the cohort of 216 subjects (175 women, 41 men) undergoing BTX‐A, 24 different periprocedural antibiotic regimens were utilized, and 98 (45%) underwent BTX‐A injections in the OR setting while 118 (55%) underwent BTX‐A injection in the office. Antibiotics were given to 86% of patients in the OR versus 77% in office, and 8.3% of subjects received BPS concordant antibiotics in the OR versus 82% in office. UTI rates did not vary significantly among the 141 subjects who received antibiotics and had 30‐day follow‐up (8% BPS‐concordant vs. 16% BPS‐discordant, CI −2.4% to 19%, p = 0.13). A sensitivity analysis of UTI rates based on procedure setting (office vs. OR) did not demonstrate any difference in UTI rates (p = 0.14).ConclusionsThis retrospective multi‐institutional study demonstrates that antibiotic regimens and adherence to the 2008 AUA BPS were highly variable among providers with lower rates of BPS concordant antibiotic use in the OR setting. UTI rates at 30 days following BTX‐A did not vary significantly based on concordance with the BPS or procedure setting.