bluuebunny/crossref_metadata_2025_split huggingface dataset:
Del concepto conquistado y la experiencia… ¿derivada?: la hiperclasificación y la hiperexclusión identitaria
Authors: Sanahuja Sonia 
Published: January 2025

En este trabajo, se recuperan planteos derivados de las agudas observaciones y críticas que despliega Élisabeth Roudinesco en El yo soberano. Ensayo sobre las derivas identitarias (2023), acerca de las conquistas traicionadas por movimientos sociales que pretendían grados diversos de emancipación, en un pasado no tan lejano, y que hoy consolidan modos de exclusión desde esencialismos que traicionan, paradójicamente, sus propuestas antiesencialistas originarias. Así mismo, se conjugan sus reflexiones con algunas ideas centrales de Judith Butler acerca de la subjetividad, el género y las políticas de identidad, a fin de tejer un diálogo no sin controversias, entre una y otra autora, y acerca de sus lecturas y apropiaciones de formulaciones originarias, como las de Michel Foucault. La reflexión subyacente se centra en las relaciones complejas entre la generación de teoría y la experiencia, lo que ubica a este abordaje en una zona de frontera en términos epistémico-metodológicos, puesto que se resuelve como un ejercicio de reflexión derivado de uno anterior con una fuerte vocación empírica. En esta dialéctica, los objetivos trazados tienen que ver con reflexionar acerca de ciertos abordajes de los fenómenos relacionados con la identidad, tanto desde el plano teórico o conceptual, como desde la perspectiva fundada en la comprensión de la experiencia como tal; así mismo, retomar hallazgos de un trabajo de investigación previo, para diversificar las formas de inquietar la relación entre el concepto y la experiencia, y, finalmente, se pretende aportar análisis y experiencias que movilicen el ejercicio de una política de identidad asentada en procesos de subjetivación dinámicos, en su inherente contingencia, a fin de fortalecer las conquistas emancipatorias emergentes del campo social, incluso desde enclaves académicos, para hacer de la diferencia una articulación concreta potencialmente transformadora a escala social.
Feasibility Study for the Development of Combination Dosage Form Containing Aspirin and Omeprazole for Treating Cardiovascular and Cerebrovascular Events
Authors: Muni Maniza , Sajeeb B K , Mou Sumaiya Sharmin , Faruqui Adeeba Jaheen , Al Mamun Md Elias 
Published: January 2025

Cardiovascular and cerebrovascular diseases are two of the major reasons of morbidity and mortality worldwide, hence require proper treatment and secondary prevention. Aspirin is a first line treatment option for the patients suffering from aforementioned issues and is usually co-administered with omeprazole to lessen the gastrointestinal side effects. A survey was done among patients, doctors, pharmaceuticals and retailers to explore the feasibility of developing a combination bilayer dosage form of aspirin and omeprazole so that the complications of co-administration can be minimized. Data were collected through direct interview and online questionnaire and statistical significance was determined using independent sample t-test. The study showed that drug utilization pattern of 85% of patients contain aspirin and omeprazole in the same prescription. Statistical data supported that both doctors and patients prefer the dose to be 75 mg for aspirin and 20 mg for omeprazole. More than 60% of each stakeholder showed their preference for the combination dosage form. Almost 50% of the doctors and patients preferred it for ease of consumption while retailers and manufactures considered the sales aspect. Moreover, ease of remembering, lesser number of pills consumption and lower price of the combination than the individual formulations came out to be the reasons for expecting availability of the combination among 68.82% of patients. As the demand of the combination and the market prediction of the pharmaceuticals matched, so introduction of fixed dose aspirin-omeprazole bilayer combination in Bangladesh can be beneficial overall.
Bangladesh Pharmaceutical Journal 28(1): 105-113, 2025 (January)
Microstructural modifications in bitumens rejuvenated by oil from pyrolysis of waste tires
Authors: Alfe Michela , Gargiulo Valentina , Ruoppolo Giovanna , Cammarota Francesco , Calandra Pietro , Oliviero Rossi Cesare , Loise Valeria , Porto Michele , Di Capua Roberto , Caputo Paolino 
Published: January 2025

IntroductionBitumen is the viscoelastic fluid binding the crushed stones and mineral aggregates in the asphalt material used to pave roads around the world. During the paving procedure, the volatile compounds are lost and oxidization occurs with variation of the mechanical characteristics (aging); thus, the material becomes rigid and brittle over time and may need replacement. Instead of being landfilled, aged asphalts can be reused in new pavements after pretreatment with specific additives to restore their original properties.MethodsBy considering conscious utilization of natural resources, we propose using the condensable fraction (oil) obtained from the pyrolysis of waste tires (WTs) as the agent to rejuvenate aged bitumen. The pyrolysis oil from WTs was produced and characterized using elemental analysis, gas chromatography coupled with mass spectrometry (GCMS), and thermogravimetry. Bitumen was aged by the rolling thin-film oven test procedure and blended with the WT pyrolysis oil at three different concentrations (1%, 3%, and 6% w/w) to evaluate the rheological behaviors. The blends were also investigated using atomic force microscopy, and the asphaltenic fraction was assessed via optical microscopy.Results and discussionAll the data consistently indicate that oil addition not only reduces the viscosity of bitumen and restores it to values close to the original unaged bitumen but also changes the intermolecular structure to recover the self-assembly pattern typical of the unaged sample. The physicochemical mechanisms of this phenomenon are proposed in light of the oil characteristics. Hence, it is concluded that the pyrolysis oil from WTs can be used to rejuvenate asphalts, which can then be used in reclaimed asphalt pavement technology. The impacts of our findings are expected to be extensive because bitumens are globally used for paving roads. In addition, since the proposed method couples/fuses urban waste treatment with asphalt maintenance processes, two types of wastes (oil from pyrolysis of WTs and aged bitumens) can be simultaneously recovered and reused to produce new and performing asphalts.
Novel MOF-based vanadium and 2,2 -bipyridine-4,4 -dicarboxylic acid as phenomenal dye adsorbent and antimicrobial agent
Authors: Mohammed Yaseen Baraa , Altalbawy Farag M. A. , Jihad Albadr Rafid , Mohammed Taher Waam , Alwan Mariem , Jasem Jawad Mahmood , Mushtaq Hiba , Muzammil Khursheed , Hussein Zwamel Ahmed 
Published: January 2025

In this study, a new MOF (metal-organic framework) based on vanadium and 2,2-bipyridine-4,4-dicarboxylic acid (V/BP-MOF) was synthesized. Synthesized V/BP-MOF was introduced as a strong adsorbent of Congo Red (CR) and an effective agent in eliminating microbial species. In the investigation of CR absorption activity, several factors such as concentration of V/BP-MOF, pH, time, and temperature were investigated. Antimicrobial evaluations were carried out on Common bacterial strains in wastewater and values of MIC (minimum inhibitory concentration) and MBC (Minimum Bactericidal Concentration) were reported. The V/BP-MOF was confirmed and characterized by EA, EDS, EDS mapping, FT-IR, XRD, TGA, BET, SEM, and TEM. In checking the characteristics of V/BP-MOF, size, specific surface area, and thermal stability were obtained, respectively, 68 nm, 325 m2/g, and 320°C. The highest adsorption of CR, at 94%, was obtained at natural pH, ambient temperature, and after 150 min. In kinetic studies, a correlation coefficient of 0.99 was observed with the pseudo-second-order kinetic model, while in isotherm studies, a correlation coefficient of 0.97 was observed with the Freundlich isotherm model. In the biological evaluations, the best inhibition was against Escherichia coli, and MIC and MBC were observed as 4 μg/mL and 2 μg/mL, respectively. As a general result, V/BP-MOF can be introduced as a potent absorbent agent of CR dye and antimicrobial properties. Therefore, the compound synthesized in this study can be introduced as a suitable option for the wastewater treatment industry, with multiple capabilities including the removal of chemical pollutants and pathogenic agents.
Acinetobacter baumannii infection in critically ill patients with COVID-19 from Tehran, Iran: the prevalence, antimicrobial resistance patterns and molecular characteristics of isolates
Authors: Ghamari Mahsa , Jabalameli Fereshteh , Afhami Shirin , Halimi Shahnaz , Emaneini Mohammad , Beigverdi Reza 
Published: January 2025

BackgroundThe COVID-19 pandemic has led to the excessive use of antimicrobials in critically ill patients. Infections caused by Acinetobacter baumannii have increased significantly both regionally and globally during the COVID-19 pandemic, posing dramatic challenges for intensive care unit (ICU) patients. This study aimed to determine the prevalence, antimicrobial resistance patterns, presence of selected antimicrobial resistance genes, and genetic diversity of A. baumannii isolates obtained from COVID-19 cases admitted to the ICU at the University Hospital in Iran.Materials and methodsThis was a cross-sectional and single-center study comprising patients with A. baumannii infections admitted to the ICU with COVID-19 between April and November 2021. The demographic and clinical data of the patients were collected. Antimicrobial susceptibility testing was conducted based on Clinical Laboratory Standards Institute guidelines. This study used PCR and multiplex PCR to investigate antibiotic resistance genes (ARGs) and global clones (GC), respectively. Genetic diversity was investigated by repetitive element sequence-based PCR (REP-PCR).ResultsThe prevalence of A. baumannii coinfection in COVID-19 cases was 8.1% (43/528). More than 90% (39/43) of A. baumannii isolates were resistant to cefepime, ampicillin-sulbactam, gentamicin, trimethoprim-sulfamethoxazole and amikacin. Furthermore, 44.2% (19/43) of isolates were resistant to colistin. There were 91% (39/43) isolates that were extensively drug-resistant (XDR). The most prevalence carbapenem resistance encoding genes were bla-OXA-23 65.1% (29/43) and blaNDM 41.8% (18/43). The most common aminoglycoside resistance genes were aac(6’)-Ib 65.1% (28/43) and ant(2)-Ia 46.5% (20/43). Isolates from the prominent Global clone GCII comprised 83.7% (36/43) of total isolates. Genetic fingerprinting using REP-PCR revealed that 39 typeable A. baumannii isolates were categorized into 12 distinct genotypes, of which 72% (28/39) of isolates belonged to one genotype.ConclusionThe high prevalence of XDR A. baumannii such as carbapenem and colistin-resistant strains, poses a significant concern for the treatment of COVID-19 patients, heightening the risk of therapeutic failure. The data demonstrate the dissemination of a single A. baumannii clone carrying multiple ARGs within our hospital. Regarding the limited therapeutic options, it is crucial to implement effective prevention and containment policies to curb the spread of these strains.
Chronic IVC occlusion caused by unopened filter after conversion: case report and literature review
Authors: Sheng Shi , Li Yiqing 
Published: January 2025

BackgroundThe VenaTech Convertible Vena Cava Filter (VTCF) is a device designed for insertion into the inferior vena cava (IVC) to prevent life-threatening pulmonary embolism (PE). Upon removal of its retrieval hook, the filter's legs are intended to expand, forming a stent-like structure that is suitable for long-term residence in the human body. However, in clinical practice, the filtering legs do not always expand fully, and the long-term effects on patients remain insufficiently studied.Materials and methodsThis report presents the case of a male patient with thrombophilia, in whom the VTCF failed to expand completely after conversion, resulting in IVC occlusion and the development of acute deep vein thrombosis (DVT) in the lower limbs. A review of the relevant literature is also provided.ConclusionThe inability of the filtering legs to fully expand after retrieval hook removal highlights a design limitation of the VTCF, necessitating proactive management during conversion to ensure complete expansion. For younger or thrombophilic patients, careful evaluation of the filter's suitability and extended follow-up are crucial to optimize outcomes.
Risk of neonatal SARS-CoV-2 infection: a retrospective cohort study based on infected mothers with gestational diabetes mellitus
Authors: Ni Jing , Zheng Yongfei , Tian Jiaqi , Zhang Lin , Duan Shuyin 
Published: January 2025

BackgroundThe COVID-19 pandemic has posed unprecedented challenges to global public health, especially for pregnant women and their offspring. However, little is known about the impact of maternal SARS-CoV-2 infection on neonatal outcomes, particularly in the context of coexisting gestational diabetes mellitus (GDM).MethodsHospitalized pregnant women with SARS-CoV-2 infection were retrospectively enrolled between November 2022 and January 2023, and matched with pregnant subjects free of SARS-CoV-2 infection based on their propensity scores. All women were tested for SARS-CoV-2 upon admission as part of routine procedures, then divided into groups of pregnant women with SARS-CoV-2 infection and GDM (SARS2+GDM), pregnant women with SARS-CoV-2 infection but without GDM (SARS2+noGDM), and pregnant women without SARS-CoV-2 infection or GDM (Normal group). A logistic regression model was used to study the risk of GDM, perinatal SARS-CoV-2 infection, and their interaction on neonatal SARS-CoV-2 infection.ResultsOf 378 pregnant women with SARS-CoV-2 infection, the neonatal infection rate was higher in the GDM group as compared to the SARS-CoV-2 infection only group, but both SARS-CoV-2 infection rates were lower than that of the normal control group. Logistic regression analysis identified an interaction between maternal SARS-CoV-2 infection and GDM on neonatal infection, where maternal SARS-CoV-2 infection (odds ratio [OR] = 0.31, 95%CI: 0.22-0.44) and vaccination for anti-SARS-CoV-2 (OR = 0.70, 95%CI: 0.50-0.98) were associated with lower odds of neonatal infection, while higher pre-pregnancy body mass index (BMI) (OR = 1.06, 95% CI: 1.02-1.10) and GDM (OR = 1.97, 95%CI: 1.21-3.21) were associated with higher odds of neonatal infection.ConclusionsWe demonstrate that the coexistence of GDM and perinatal SARS-CoV-2 infection was associated with an increased probability of neonatal SARS-CoV-2 infection.
Can Ethiopia eliminate malaria? Malaria burden: insights from the pre-elimination era, current challenges and perspectives
Authors: Woldesenbet Dagmawi , Tegegne Yalewayker , Mussema Abdulhakim , Tamene Elias , Mohamed Kemal , Abebe Wagaw , Mekuria Melese , Bogale Kasahun , Geremew Habtamu , Shifa Mufta Muzemil , Tegegne Mulugeta Aemero 
Published: January 2025

BackgroundEthiopia has faced a significant burden of malaria, enduring endemic transmission in various regions. Despite concerted efforts spanning years, malaria remains a persistent public health issue, particularly affecting underserved rural communities. Previous developments in vector control, diagnostic capabilities, and treatment protocols have led to notable reductions in malaria morbidity and mortality. However, challenges persist, including the emergence of drug and insecticide resistance, compounded by environmental and demographic factors. Understanding the historical context and contemporary challenges is crucial for navigating Ethiopia’s path toward malaria elimination.MethodsFrom October 2023 to January 2024, a systematic search was conducted across open access journals such as PubMed, EMBASE, CINALH, Web of Science, Global Health, and Google Scholar using MeSH and Emtree terms for malaria. The focus was on challenges of malaria elimination in Ethiopia, such as drug resistance, vectors’ insecticide resistance and the loss of the diagnostic potential of rapid diagnostic kits.Main textRecent trend analyses and World Health Organization reports indicate resurgence in malaria cases in Ethiopia. Factors contributing to this resurgence include emerging drug resistance, insecticide resistance, and genetic mutations such as single nucleotide polymorphisms. Other challenges include the spreading resistance to effective antimalarial drugs, socio-cultural barriers to malaria elimination, the challenge posed by Plasmodium vivax in elimination efforts, and the occurrence of imported cases in previously low burden areas. To reverse the rising trend of malaria cases, it is necessary to customize intervention strategies through active community engagement, rigorous healthcare infrastructure, and learning from countries that have successfully eliminated malaria.ConclusionWhile past successes are notable, they do not guarantee current progress, highlighting the need for rigorous implementation of strategies and adaptation of intervention methods to ensure the success of malaria elimination efforts. However, recent data suggests a concerning resurgence in malaria cases, potentially fueled by emerging drug and insecticide resistance. To achieve sustained success in malaria elimination, there is an urgent need for continued vigilance, customization of intervention strategies, and robust collaboration between stakeholders to address these challenges effectively.
The diagnostic value and efficacy evaluation of lung ultrasound score in neonatal respiratory distress syndrome: a prospective observational study
Authors: Dong Jian , Deng Yuhong , Tong Jin , Du Tingting , Liu Wenguang , Guo Yan 
Published: January 2025

ObjectiveTo evaluate the diagnostic efficacy and determine the optimal cut-off values of lung ultrasound score for diagnosing neonatal respiratory distress syndrome and its accuracy in assessing the efficacy of neonatal respiratory distress syndrome.MethodThis prospective study included 100 neonates with suspected neonatal respiratory distress syndrome. Each patient underwent both the 14-zone and 12-zone lung ultrasound methods, as well as a chest x-ray, performed after birth and before initiating drug treatment. Surfactant replacement therapy was administered to patients who were diagnosed with neonatal respiratory distress syndrome and met the criteria for medication. Lung ultrasound was conducted and recorded at the 24th hour, the 48th hour, the 72nd hour, and the 7th day after drug administration. ROC curve analysis, Kappa statistics, and ANOVA were utilized to identify the optimal cut-off values for the lung ultrasound scores in diagnosing neonatal respiratory distress syndrome.Results89 neonates were diagnosed with respiratory distress syndrome, of whom 64 received surfactant replacement therapy. The mean scores of 12-zone lung ultrasound score, 14-zone lung ultrasound score, and chest x-ray score are 18.22 ± 7.15, 38.92 ± 9.69, and 2.15 ± 0.97, respectively. The diagnostic AUC for the 12-zone lung ultrasound score is 0.84 (95% CI: 0.73–0.95), with an optimal cut-off value of 13.5 for diseased vs. not diseased, while the AUC for the 14-zone lung ultrasound score is 0.88 (95% CI: 0.76–0.99), with an optimal cut-off value of 34 for diseased vs. not diseased. There is significant concordance between the neonatal lung ultrasonography scores and the chest x-ray score for diagnosis respiratory distress syndrome (P &lt; 0.01). The optimal cut-off values for the grading diagnosis of neonatal respiratory distress syndrome using the 14-zone lung ultrasound score are identified as 36.5, 40.5, and 44.5. The 12-zone lung ultrasound score does not have a significant difference between the 12th hour after receiving surfactant replacement therapy and the 48th hour after treatment (P = 0.08). All other comparisons demonstrated significant differences.ConclusionThe 14-zone lung ultrasound score demonstrates higher diagnostic efficacy in diagnosing neonatal respiratory distress syndrome and can accurately evaluate the early efficacy of surfactant replacement therapy in neonates.
Exploring the effects of combined nostalgic activities and music therapy on Alzheimer's disease outcomes
Authors: Zhang Yunqiu , Wang Yunqiong , Liu Qiao , Xiao Jun , Huang Ling , Zhou Lan , Liu Xuemei 
Published: January 2025

ObjectiveExploring the effects of combination of nostalgic activity-based therapies, including music therapy on cognitive function, negative emotions, and sleep quality in patients with mild to moderate Alzheimer's disease.MethodsA total of 63 patients with mild to moderate Alzheimer's disease who were treated at the Sichuan Provincial Psychiatric Center of the People's Hospital of Sichuan Province from January to June 2023 were selected as the research subjects. They were randomly divided into a study group (n = 31) and a control group (n = 32) using a random number table method. The control group received routine treatment and nursing care, while the study group received nostalgic music therapy intervention on the basis of the control group. The Mini Mental State Examination (MMSE), Montreal Cognitive Assessment Scale (MOCA), Self Rating Anxiety and Depression Scale (SAS, SDS), and Pittsburgh Sleep Quality Index (PSQI) of the two groups were compared.ResultsA total of 30 cases from each group completed the study. After 12 weeks of intervention, the MMSE and MOCA scores of both groups of patients increased, and the treatment group was higher than the control group (P &lt; 0.05); SAS, SDS and PSQI scores decreased compared with those before intervention, and the treatment group was lower than the control group (P &lt; 0.05).ConclusionNostalgic music therapy can improve cognitive function, alleviate negative emotions, and improve sleep quality in patients with mild to moderate Alzheimer's disease.
Effect of leisure-time physical activity on depression and depressive symptoms in menopausal women: a systematic review and meta-analysis of randomized controlled trials
Authors: Liu Rong , Tang Xun 
Published: January 2025

AimsMenopausal women often suffer from depression, which impairs their quality of life. Physical activity has been reported to exert beneficial effects on preventing and treating depression. This meta-analysis aims to explore the effect of leisure-time physical activity on determined depression or depressive symptoms in menopausal women.MethodsRelevant studies were searched from PubMed, Embase, Cochrane Library, Web of Science, PsycINFO, CINAHL Plus, China National Knowledge Infrastructure (CNKI), VIP, and WanFang databases. Outcomes were depression or depressive symptoms. Weighted mean difference (WMD) or standard mean difference (SMD) with 95% confidence interval (CI) was used as the statistical measure. Heterogeneity tests were performed for each outcome, and all outcomes were subjected to sensitivity analysis. Subgroup analysis was performed based on depression degree, exercise intensity, exercise form, intervention duration, supervision, sample size, and geographical region.ResultsA total of 17 studies were included in this meta-analysis. The results showed that exercise alleviated the depressive symptoms of menopausal women (SMD = −1.23; 95% CI, −2.21 to −0.24). In addition, exercise was found to reduce the depression (SMD = 11.45; 95% CI, −1.75 to −1.15), and depression assessed by the Center for Epidemiologic Studies Depression Scale (CES-D) (WMD = −5.76; 95% CI, −6.63 to −4.89) or Self-Rating Depression Scale (SDS) (WMD = −6.86; 95% CI, −9.24 to −4.49). The results were similar regardless of depression degrees, exercise intensity, intervention duration, exercise form, supervision or not, sample size, and geographical region.ConclusionsLeisure-time physical activity may help alleviate depressive symptoms or depression in menopausal women. However, further high-quality studies are needed to confirm these findings and better understand the specific effects of physical activity on depression in this population.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/, identifier CRD42024581087.