bluuebunny/crossref_metadata_2025_split huggingface dataset:
Internet-based psychoeducation and support programme for relatives of young people with early psychosis: results of the first German-language intervention
Authors: Rus-Calafell Mar , Teismann Tobias , Kullmann Fine , Alatas Dilara , Ballero-Reque Cristina , Holewa Julia , Rüsberg Marilena , Brüne Martin , Paino Mercedes , Schneider Silvia 
Published: January 2024

BackgroundInternational clinical guidelines recommend Family Interventions (FIs) especially for families of people at early stages of psychosis. The German S3 treatment guideline for schizophrenia gives FIs the highest level of clinical recommendation. However, some family relatives have limited access to these services due to health system constrains. Digital interventions have emerged as a solution to overcome this hindered access to evidence-based family interventions.ObjectiveThe present pilot study evaluates the feasibility and potential efficacy of the first German moderated online psychoeducation and support programme (ePSP) for relatives of people with early psychosis, with the additional purpose to improve accessibility and reduce waiting times.MethodsA pre-post study was performed. A brief recruitment period was pre-established (10 weeks) to test potential improvement of regular therapy waiting times in Germany. A total of 25 relatives of people with early psychosis were recruited and received the 12-week moderated online intervention. Assessments were conducted at baseline and at post intervention. Acceptance of the intervention and the user’s experience were also evaluated at post intervention.ResultsRecruitment, retention rates and qualitative data support the feasibility and acceptability of the ePSP. Significant positive effects of the interventions were found on key therapeutic targets, including both primary outcomes (i.e., perceived stress and beliefs about the illness). Twenty-one participants also completed the open-ended questions of the user experience questionnaire, which yielded three main themes: most important modules, difficulties in using the programme and ways to improve ePSP.DiscussionThese results provide preliminary efficacy estimates for a fully powered RCT to investigate superiority (or equipoise) effects of the ePSP in comparison to the routine face-to-face family therapy groups. This future RCT will also allow further exploration of ePSP to improve access to psychological therapy for relatives of young people with psychosis, also in relation to the new ground-breaking Digital Healthcare Act in Germany.
Smartphone-delivered multicomponent lifestyle medicine intervention for improving mental health in a nonclinical population: a randomized controlled trial
Authors: Wong Vincent Wing-Hei , Tong Jessica Tsz-Yan , Shi Nga-Kwan , Ng Chee H. , Sarris Jerome , Ho Fiona Yan-Yee 
Published: January 2024

ObjectiveTo prevent the exacerbation of mental health burdens, a growing body of research has recommended a balanced approach that emphasizes both the delivery of mental health treatments to individuals with common mental disorders (CMDs) and the strengthening of protective factors for CMDs among nonclinical populations. This randomized controlled trial (RCT) evaluated the efficacy of a smartphone-delivered multicomponent lifestyle medicine (LM) intervention, Lifestyle Hub, for improving mental health among a nonclinical population of Chinese adults.MethodsA total of 106 participants with Patient Health Questionnaire-9 total score &lt; 10 and Generalized Anxiety Disorder 7-Item Scale &lt;8 were randomly assigned to either the Lifestyle Hub intervention group (LH, n = 53) or the waitlist control group (WL, n = 53). Lifestyle Hub is an 8-week smartphone-delivered multicomponent LM intervention developed based on the transtheoretical model. The intervention components included lifestyle psychoeducation, physical activity, diet and nutrition, stress management, sleep management, and motivation and goal-setting techniques. Assessments were conducted at baseline, immediate post-intervention, and 1-month follow-up (LH only).ResultsThe linear mixed effect model based on the intention-to-treat principle indicated that Lifestyle Hub significantly improved overall mental health, depressive symptoms, anxiety symptoms, stress, insomnia severity, overall health-promoting behaviors, dietary quality, and stress management compared to the WL group at immediate post-intervention (d = 0.13–0.56). No significant between-group differences were observed in terms of functional impairment, health-related quality of life, health responsibility, physical activity level, spiritual growth, and interpersonal relations. The intervention gains in the LH group were maintained at 1-month follow-up. The LH participants indicated that Lifestyle Hub was an acceptable intervention for improving mental health, although a significantly higher level of study attrition was observed in the LH group (20.8%) relative to the WL group (5.7%).ConclusionLifestyle Hub may serve as an efficacious and acceptable intervention for improving mental health in nonclinical adult populations. To extend the benefits of LM interventions at the population level, future studies are warranted to examine a stepped-care approach to delivering LM interventions.Trial registration: This randomized controlled trial was pre-registered with ClinicalTrials.gov (NCT04295369).
Mortality rates from asbestos-related diseases in Italy during the first year of the COVID-19 pandemic
Authors: Fazzo Lucia , Grande Enrico , Zona Amerigo , Minelli Giada , Crialesi Roberta , Iavarone Ivano , Grippo Francesco 
Published: January 2024

Background and aimPatients with interstitial lung diseases, including asbestosis, showed high susceptibility to the SARS-CoV-2 virus and a high risk of severe COVID-19 symptoms. Italy, highly impacted by asbestos-related diseases, in 2020 was among the European countries with the highest number of COVID-19 cases. The mortality related to malignant mesotheliomas and asbestosis in 2020 and its relationship with COVID-19 in Italy are investigated.MethodsAll death certificates involving malignant mesotheliomas or asbestosis in 2010–2020 and those involving COVID-19 in 2020 were retrieved from the National Registry of Causes of Death. Annual mortality rates and rate ratios (RRs) of 2020 and 2010–2014 compared to 2015–2019 were calculated. The association between malignant pleural mesothelioma (MPM) and asbestosis with COVID-19 in deceased adults ≥80 years old was evaluated through a logistic regression analysis (odds ratios: ORs), using MPM and asbestosis deaths COVID-19-free as the reference group. The hospitalization for asbestosis in 2010–2020, based on National Hospital Discharge Database, was analyzed.ResultsIn 2020, 746,343 people died; out of them, 1,348 involved MPM and 286 involved asbestosis. Compared to the period 2015–2019, the mortality involving the two diseases decreased in age groups below 80 years; meanwhile, an increasing trend was observed in subjects aged 80 years and older, with a relative mortality risks of 1.10 for MPM and 1.17 for asbestosis. In subjects aged ≥80 years, deaths with COVID-19 were less likely to have MPM in both genders (men: OR = 0.22; women: OR = 0.44), while no departure was observed for asbestosis. A decrease in hospitalization in 2020 with respect to those in 2010–2019 in all age groups, both considering asbestosis as the primary or secondary diagnosis, was observed.ConclusionsThe increasing mortality involving asbestosis and, even if of slight entity, MPM, observed in people aged over 80 years during the 1st year of the COVID-19 pandemic, aligned in part with the previous temporal trend, could be due to several factors. Although no positive association with COVID-19 mortality was observed, the decrease in hospitalizations for asbestosis among individuals aged over 80 years, coupled with the increase in deaths, highlights the importance of enhancing home-based assistance during the pandemic periods for vulnerable patients with asbestos-related conditions.
Factors affecting the medication literacy of older adults and targeted initiatives for improvement: a cross-sectional study in central China
Authors: Mei Chao , Xu Baoli , Cai Xuefeng , Wan Min , Zhao Zhigang , Lv Yongning , Zhang Yu , You Ruxu 
Published: January 2024

IntroductionThis study explored the state of rational drug use among older adults in central China, aiming to unveil factors influencing their medication literacy and proposing targeted improvement measures.MethodsA cross-sectional study involving 454 participants aged 60 and above was conducted in Hubei province between February 1 and May 30, 2023, with data collected through face-to-face interviews by pharmacists. Multiple logistic regression analysis was conducted to determine factors that affected medication literacy.ResultsOf the 412 valid questionnaires, findings revealed inadequate knowledge of rational drug use among older adults in central China. Those who fully understood (105, 25.49%, OR = 9.349, p &lt; 0.001, 95%CI = 3.884–22.502) or partially understood (228, 55.34%, OR = 3.295, p = 0.002, 95%CI = 1.548–7.013) drug instructions exhibited significantly higher medication literacy than those who did not understand (79, 19.17%). Subsequent research revealed a lack of awareness in reading drug instructions or difficulty in understanding them. Most older adults seldom heard of but exhibited high acceptance of medication guidance services.DiscussionIn conclusion, the ability to comprehend drug instructions significantly influenced the medication literacy of older adults. Initiatives such as revising age-appropriate drug instructions could effectively enhance rational drug use among this demographic.
5-(Benzoyloxymethyl)isoxazole-3-carboxylic Acid Ethyl Ester
Authors: Antonini Cosimo , Cordero Franca M. , Machetti Fabrizio 
Published: January 2024

We describe here the palladium hydrogenation of ethyl 5-(benzoyloxymethyl)isoxazole-3-carboxylate. The presence of two reducible sites in the molecule, namely the benzylic-like position and the isoxazole N–O bond, creates a possible competition. The results show that under the applied conditions, ethyl (Z)-2-amino-4-oxo-2-pentanoate is obtained as the only product. Accordingly, a domino process occurs, consisting of deoxygenation to the 5-methylisoxazole derivative followed by reductive opening of the isoxazole ring. The isoxazole substrate was prepared by NaOH-catalyzed cycloaddition-condensation of ethyl nitroacetate and propargyl benzoate in water. Complete characterizations of the isoxazole and Z-enaminone derivatives are reported.
Efecto de la temperatura de secado sobre los compuestos polifenólicos y actividad antioxidante de las hojas de Piper aduncum L. (matico).
Authors: Luna Fox Sting Brayan , González-Linares Katherine Estefanía , Ortega Torres Jhomaira Astrid , Rodríguez-Almeida Nancy Narcisa , Dahua-Gualinga Ruth Dayra , Peñafiel-Bonilla Nelly Jazmín , Bravo-Sánchez Luis Ramón 
Published: January 2024

El objetivo de la investigación fue evaluar el efecto de la temperatura de secado sobre los compuestos polifenólicos y actividad antioxidante de las hojas de Piper aduncum L. (matico). Las hojas fueron recolectadas en la ciudad de Puyo-sector El Paico, ubicado en la Amazonía de la provincia de Pastaza-Ecuador. Se utilizó la técnica extracción asistida por ultrasonido para obtener los extractos acuosos. Los polifenoles totales fueron determinados mediante la técnica de Folin-Ciocalteu y la actividad antioxidante fue evaluada utilizando los métodos FRAP y ABTS. Se evaluó el efecto de tres niveles de temperatura de secado (45, 50 y 55°C) sobre los compuestos polifenólicos y la actividad antioxidante de las hojas de matico. Se usó el software Design Expert versión 10, para evaluar la significancia (p<0,05) del factor de estudio sobre la respuesta experimental. Se realizó el análisis ANOVA para valorar la influencia que tuvo la temperatura sobre las variables de respuesta. La temperatura de secado tuvo un efecto negativo sobre los compuestos polifenólicos y la actividad antioxidante en las hojas del matico. Los resultados más altos se obtuvieron a 45°C con valores de 79,92 mg Equivalentes de Ácido gálico por cada 100 gramos de materia seca para polifenoles totales, 74898,90 y 508,07 µg Equivalentes de TROLOX por gramo de materia seca, para actividad antioxidante mediante las técnicas FRAP y ABTS respectivamente, por lo que es recomendable realizar el secado a esta temperatura, previo a cualquier utilización o procesamiento posterior con vistas a preservar sus propiedades como antioxidante natural.
Palabras Clave: Polifenoles totales, capacidad antioxidante, FRAP, ABTS.
New evidence on the validity of the selection methods for recruitment to general practice training: a cohort study
Authors: Tiffin Paul A , Morley Emma , Paton Lewis W , Patterson Fiona 
Published: January 2024

Background
Selection into UK-based GP training has used the Multi-Specialty Recruitment Assessment (MSRA) and a face-to-face selection centre (SC). The MSRA comprises of a situational judgement test and clinical problem-solving test. The SC was suspended during the COVID-19 pandemic. Evidence is needed to guide national and international selection policy.

Aim
To evaluate the validity of GP training selection.

Design & setting
A retrospective cohort study using data from UK-based national recruitment to GP training, from 2015–2021.

Method
Data were available for 32 215 GP training applicants. The ability of scores from the specialty selection process to predict subsequent performance in the Clinical Skills Assessment (CSA) of the Membership of the Royal College of General Practitioners examination was modelled using path analysis. The effect sizes for sex, professional family background, and world region of qualification were estimated.

Results

All component scores of the selection process demonstrated statistically significant independent relationships with CSA performance (
P
<0.001), thus establishing their predictive validity. All were sensitive to demographic factors. The SC scores had the weakest relationship with future CSA performance. However, for candidates with MSRA scores below the lowest quartile, the relative contribution of the SC scores to predicting CSA performance was similar to that observed for MSRA components.

Conclusion
The MSRA has predictive validity in this context. Re-instituting an SC for those with relatively low MSRA scores should be considered. However, the relative costs and potential advantages and disadvantages should be carefully weighed.
New in Transfusiology (at the Congress of the International Society of Blood Transfusion in Cape Town)
Authors: Жибурт Е.Б. , Хамитов Р.Г. , Похабов Д.С. , Аверьянов Е.Г. , Кожемяко О.В. , Кузьмин Н.С. , Мадзаев С.Р. , Шестаков Е.А. 
Published: January 2024

В статье обобщены материалы 34-го регионального конгресса Международного общества переливания крови. Проанализированы данные по организации донорства и службы крови, инфекциям у доноров крови, обеспечению качества компонентов крови, инактивации патогенов, иммуногематологии, эффективности и безопасности переливания крови, менеджменту крови пациента.
The article summarizes the materials of the 34th regional congress of the International Society of Blood Transfusion. Data on the organization of blood donation and blood services, infections in blood donors, quality assurance of blood components, inactivation of pathogens, immunohematology, the effectiveness and safety of blood transfusion, and patient blood management were analyzed.
Analisis Hambatan Samping Terhadap Tingkat Pelayanan Jalan Pada Ruas Jalan Ahmad Yani Kota Maumere
Authors: Yuniaty Fortunata Rosalina , Karels Dolly W. , Ramang Ruslan 
Published: January 2024

The increase in development in an area and the increase in population cause the need to pay attention to facilities and infrastructure in the field of transportation, especially roads. Maumere is the capital of the Sikka district. The increasing need of the people of Maumere City for traffic movement causes road performance to decrease because traffic movement exceeds the existing road capacity. Side friction occur on this road section because there are several offices, schools, shopping centers, and restaurants and are the route in and out of campuses, schools, shops, and markets. The purpose of the study is to determine the side friction of working days and holidays, the level of service of working days and holidays, and the effect of side friction on the level of road services. The method used in the research is quantitative based on PKJI 2014. The results of the weekday side friction analysis showed that the value of side friction reached 1,286 events/hour and included very high side friction classes and holidays showed that the side resistance factors reached 125 events/hour and included low side friction classes. The road service level value on weekdays is B and the holiday road service level value is B. The value of the side friction class on weekdays is high and the value of the road service level is B. while on holidays the value of the side friction class is very low and the value of the road service level is B.
Core–shell yarn-structured triboelectric nanogenerator for harvesting both waterdrop and biomechanics energies
Authors: Wang Haitao , Kurokawa Yasuyoshi , Zhang Jia-Han , Gotoh Kazuhiro , Liu Xin , Miyamoto Satoru , Usami Noritaka 
Published: January 2024

Abstract
Wearable energy harvesters (WEHs) have garnered significant attention recently due to their promising capabilities in powering wearable devices. In this research, we present a core–shell yarn-structured triboelectric nanogenerator (CY-TENG) that operates in two modes: the single-electrode TENG (SE-TENG) and the droplet-based electricity generator. This design facilitates energy harvesting from both waterdrops and biomechanics. The CY-TENG is fabricated using fluorinated ethylene propylene ultrafine heat-shrink tubes combined with stainless-steel yarns, ensuring its flexibility, durability, and weavability. Such attributes underscore its potential as a dual-function WEH.
PELATIHAN SABLON BAGI KOMUNITAS UNTUK MENINGKATKAN KEAHLIAN USAHA DAN PELUANG BISNIS BERBASIS IT
Authors: Jarti Nanda , Jamal Siti Aisyah , Putri Weni Lestari 
Published: January 2024

ABSTRAK
Kegiatan Pengabdian kepada masyarata adalah salah satu bagian dari Tri Dharma Perguruan Tinggi dengan adanya pelaksanaan pengabdian masyarakat ini turut membantu dalam memberikan solusi terhadap asalah yang ada di tengah masyarakat untuk turut mendukung kesejahteraan dalam IPTEK, Salah satu sasaran pengabdian masyarakat yang akan dilakukan adalah pada komunitas pemuda kampung Bagan Piayu. Kegiatan-kegiatan yang dilakukan di komunitas pemuda kampung bagan piayu adalah pelatihan sablon bagi pemuda atau masyarakat yang bertujuan agar pemuda dan masyarakat piayu agar dapat mengembangkan potensi keterampilan (skill) sebagai modal membuka peluang bisnis serta bisa mengembangkan dan menghasilkan output berupa suatu produk yang kreatif. Metode Pelaksanaan kegiatan pelatihan sablon akan diawali denga memberikan pengetahuan serta mendemostrasikan tentang cara dan proses menyablon kemudian memberikan pengetahuan terkait strategi dalam proses dan cara menyablon pada media kaos. Pada pelatihan ini peserta memahami strategi dalam memulai bisnis sablon sehingga termotivasi untuk membuka lapangan kerja secara mandiri dalam bisnis percetakan.
Kata Kunci: Pelatihan,Sablon,IT
ABSTRACT
Community service activities are one part of the Tri Dharma of Higher Education, with the implementation of communityservice helping to provide solutions to problems that exist in society to help support prosperity in science and technology.One of the targets of community service that will be carried out is in the youth community. Bagan Piayu village. The activities carried out in the Bagan Piayu village youth community are screen printing training for youth or the community which aims to enable the Piayu youth and community to develop potential skills as capital to open business opportunities and be able to develop and produce output in the form of a creative product. Method of implementing screen printing training activities will begin by providing knowledge and demonstrating the method and process of screen printing, then providing knowledge regarding strategies in the process and how to screen print on t-shirt media. In this training,participants understand strategies for starting a screen printing business so that they are motivated to create independent employment opportunities in the printing business.
Keywords: Training, Screen Printing, IT
SOSIALISASI PENDALAMAN KIAT SUKSES UKM MANDIRI DI KELURAHAN SEMBULANG, KECAMATAN GALANG
Authors: Rahman Syahputra  , Mustaqim Haji , Septiani Rosita 
Published: January 2024

ABSTRAK
PKM dilakukan di Kampung Labu Labi yang terletak di Kelurahan Sembulang, Kecamatan Galang, Kota Batam, Provinsi Kepulauan Riau. Kampung Labu Labi memiliki potensi alam berupa hasil laut yang melimpah sehingga Sebagian besar warga berprofesi sebagai nelayan. Namun demikian sebagian warga juga banyak yang membuat UKM baik yang memanfaatkan hasil kekayaan laut sebagai bahan baku maupun yang menggunakan bahan baku dari hasil lain. UKM ini diharapkan mampu menjadi motor penggerak peningkatan ekonomi dan kreativitas masyarakat setempat baik itu di sektor UMKM maupun di sektor pariwisata. Tujuan Pengabdian ini dilakukan untuk memberikan sosialisasi kepada masyarakat khususnya warga kelurahan sembulang, kecamatan galang terkait dengan kiat sukses dalam mengelola UKM untuk menciptakan kesejahteraan dan lapangan kerja bagi warga setempat. Metode kegiatan ini adalah Participatory Action Research (PAR), yang menekankan pada kolaborasi antara penulis dan komunitas UKM yang diteliti. Adapun hasil dari pengabdian ini menunjukkan UKM yang terdapat di kelurahan sembulang kecamatan galang dianggap sudah berjalan dengan baik namun masih dianggap perlu untuk dilakukan penyuluhan-penyuluhan agar manajemen dan tata kelola dapat berjalan lebih maksimal dan menjadi unggulan.
Kata Kunci: Kampung Labu Labi, UKM Mandiri, Pengabdian Masyarakat
ABSTRACT
PKM was carried out in Labu Labi Village which is located in Sembulang Village, Galang District, Batam City, Riau Islands Province. Labu Labi Village has natural potential in the form of abundant marine products so that most of the resident work as fishermen. However, many residents also create SMEs, either using marine resources as raw materials or using raw materials from other products. It is hoped that this UKM will be able to become a driving force for economic improvement and creativity in the local community, both in the MSME sector and in the tourism sector. The aim of this service is to provide outreach to the community, especially residents of Sembulang sub-district, Galang sub-district regarding tips for success in managing SMEs to create prosperity and employment opportunities for local residents. The method of this activity is Participatory Action Research (PAR), which emphasizes collaboration between the author and the UKM community being studied. The results of this service show that SMEs in Sembulang sub-district, Galang sub-district are considered to be running well but it is still deemed necessary to carry out outreach so that management and governance can run more optimally and become superior.
Keywords: Labu Labi Village, Independent SMEs, Community Service