bluuebunny/crossref_metadata_2025_split huggingface dataset:
Une pratique romaine : le tirage au sort dans l’attribution des terres
Authors: Guillaumin Jean‑Yves 
Published: January 2025

Les traités des arpenteurs romains exposent les pratiques concernant la répartition des terres entre les futurs colons. Le lot individuel est toujours présenté comme la récompense donnée au soldat devenu « vétéran ». Il est attribué par sortitio. Ce procédé est évoqué en deux passages du corpus « gromatique », l’un chez Hygin le Gromatique, l’autre chez son homonyme Hygin, qui décrivent ses différentes étapes et le matériel requis. Plusieurs textes insistent sur le caractère égalitaire et incontestable du tirage au sort pour l’attribution des lots de terre. Tous ces éléments sont confirmés par un document épigraphique rare, récemment découvert en Espagne.
Tirage au sort et jeux de chance dans le monde gréco-romain
Authors: Dasen Véronique 
Published: January 2025

Peut-on comparer le tirage au sort à une activité ludique ? Textes, images et objets témoignent de nombreuses contiguïtés, comme l’importance de la parité qui définit le cercle des joueurs tout comme celui des individus admis au tirage au sort. De profondes différences émergent aussi dans le rapport à la chance et à la volonté divine. Le résultat d’une procédure de sortitio est associé à l’idée d’équité, et donne à un groupe défini une souveraineté incontestée. Le jeu met en œuvre une dynamique propitiatoire. Il peut constituer une forme de négociation avec les dieux quand une nouvelle partie reprend ou que le lancer du dé ou d’un osselet est répété jusqu’à obtenir le coup ou la configuration de coups gagnants.
La sortitio des provinciae quaestoriae à l’époque républicaine
Authors: Díaz Fernández Alejandro , Pina Polo Francisco 
Published: January 2025

Comme la plupart des magistrats romains, les questeurs recevaient traditionnellement leurs tâches ou provinciae par sortitio ; cependant, de la même façon que l’exercice de la questure était subordonné à une autorité supérieure, qu’il s’agisse du Sénat ou des magistrats dotés de l’imperium, la procédure de sélection des provinces et du tirage au sort était elle aussi soumise aux décisions qui concernaient les provinces et les mandats des magistrats supérieurs. Partant de ce constat, cet article analyse les règles qui déterminaient l’attribution des provinces aux questeurs à l’époque républicaine.
Vote et tirage au sort
Authors: Chillet Clément 
Published: January 2025

Le tirage au sort dans la Rome républicaine est présent de manière marginale dans le processus du vote comitial. Utilisé pour la structuration du corps votant, pour la mise en place pratique de l’expression du suffrage des citoyens, enfin dans l’établissement des résultats du vote. En revanche, il est totalement exclu de deux champs : la constitution du corps civique et la procédure même de désignation. Ces éléments permettent de conclure que le système romain cherche à préserver deux principes qui constituent ses fondements : une conception universelle du corps civique et un respect des degrés de dignité sociale.
Ad urnam potestatis
Authors: Agusta‑Boularot Sandrine 
Published: January 2025

Dans le cadre de l’étude sur frais nouveaux de la collection épigraphique de la cité de Narbonne, capitale de la province de Gaule Narbonnaise, l’inscription ILN Narbonne, n° 36 (CIL XII, n° 4341) a fait l’objet d’une nouvelle interprétation. Le terme urna avait conduit, dès le xixe siècle, à mettre cette inscription en relation avec l’eau et à voir dans son support – un fragment de couronnement qui porte, sur chacune de ces faces, un texte – un élément de fontaine. Grâce à des études récentes sur les quelques inscriptions conservées qui mentionnent le terme urna, cet article propose d’interpréter ce bloc comme le vestige d’une machine à tirer au sort (ou à voter ?) monumentale.
Définir l'épopée en Grèce ancienne
Authors: Kimmel-Clauzet Flore 
Published: January 2025

En Grèce ancienne, l’épopée, en tant que genre littéraire, a été en grande partie éclipsée par la place prééminente accordée au « divin Homère » dans tous les domaines de la culture. Modèle absolu, non seulement de toute forme de poésie, mais aussi de toute littérature, source de tous les savoirs, Homère est irréductible au genre épique. Or, la dimension d’autorité qui lui est conférée ne laisse guère de place pour d’autres poètes. En outre, contrairement à la tragédie ou à la comédie par exemple, l’épopée n’a pas de nom spécifique : elle est souvent désignée uniquement au moyen du terme poiēsis, « poésie », ou reçoit des appellations diverses liées au vers employé, l’hexamètre dactylique.Toutefois, un certain nombre de grammairiens d’époques impériale et byzantine remettent sur le métier les définitions de la poésie épique. Le présent volume prend le parti de se fonder sur ces conceptions tardives et retrace leur formation à partir des textes plus anciens. Hérodote, Platon et, bien sûr, Aristote proposent déjà des définitions partielles et partisanes, mais déterminantes pour celles qui suivront.Quelles sont les diverses appellations du genre épique ? Comment est-il caractérisé ? Comment les Anciens le conçoivent-ils au sein des genres littéraires ? Analysant la formation des définitions du genre épique et donnant accès à un corpus de textes théoriques traduits ici pour la première fois en langue moderne, l’ouvrage, qui s’adresse aussi à un public non-helléniste, se veut utile à toute personne s’intéressant aux théories de l’épopée, et plus largement, aux théories des genres littéraires.
La corrispondenza del nunzio Giovanni Battista Pamphilj e le relazioni con la Spagna nella prima metà del XVII secolo
Authors: Emiliani Valentina 
Published: January 2025

Lo studio intende individuare uno schema delle relazioni stabilite dal nunzio Giovanni Battista Pamphilj a Madrid (1626-1630) attraverso l’analisi delle lettere di congratulazioni ricevute per la sua promozione cardinalizia (1629-1630) e per la sua elezione al soglio pontificio nel 1644, quando assunse il nome di Innocenzo X. Attraverso l’ausilio del database Fichoz è stato possibile raccogliere dati sui mittenti e comprendere come il nunzio costruì una rete di conoscenze con l’élite spagnola, tra cui alcuni esponenti dei monasteri femminili di Madrid.
De la glace souterraine au-delà des limites de la cryosphère. Fonctionnement glaciologique et usages de la Grande Glacière du Parmelan (massif des Bornes, France)
Authors: Ravanel Ludovic , Flinois Guillaume , Jaillet Stéphane , Malet Emmanuel , Magnin Florence , Rigal Didier , Burnet Hugo , Hobléa Fabien 
Published: January 2025

Au sein de la cryosphère, les glacières sont parmi les objets les moins bien connus. Il s’agit de grottes ou de gouffres dont la morphologie permet des conditions micro-climatiques favorables au développement ou au maintien d’accumulations de glace pérennes. Très peu de recherches ont été effectuées sur le territoire français sur ces formes de permafrost que l’on peut qualifier d’azonal. Cet article entend comprendre, à travers une approche multi-méthode, les dynamiques glaciologiques et thermiques sur une année ainsi que les usages et le potentiel paléoenvironnemental d’une glacière de moyenne altitude dans les Alpes : la Grande Glacière du Parmelan (1605 m d’altitude, massif des Bornes, Haute-Savoie, France). Un levé topographique par balayage laser terrestre a montré la présence actuelle d’au moins 8800 m3 de glace à l’intérieur de laquelle des bois ont été datés (14C) entre 1260 ± 30 BP et 120 ± 30 BP, rappelant le rôle potentiel d’archives paléo-environnementales des glacières. Si la glace de la Grande Glacière a été une ressource renouvelable et exploitée par le passé, le suivi a montré des pertes d’épaisseur pluricentimétrique à pluridécimétrique en une année, malgré quelques accumulations locales de glace saisonnière. Connectée au réseau karstique sous-jacent (glacière dite « dynamique ») qui tend à la réchauffer et présentant une température moyenne annuelle autour de 0 °C, la Grande Glacière semble proche d’un point de bascule.
Indoleamine 2,3-Dioxygenase 1/Aryl Hydrocarbon Receptor Feedback Loop Mediates Anti-inflammation in lipopolysaccharide-stimulated Astrocytes to Dampen Inflammatory Neurotoxicity
Authors: Gan Yu-Ling , Lee Yi-Hsuan 
Published: January 2025

Abstract
Aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that regulates cell immune responses in a cell type-specific and ligand-dependent manner. In the central nervous system, astrocytic AhR plays important roles in regulating neuroinflammation by mediating responses to endogenous ligands generated from the inflammation-induced indoleamine 2,3-dioxygenase 1 (IDO1)/kynurenine (KYN) pathway. We previously demonstrated that reduction of AhR expression decreases lipopolysaccharide (LPS)-induced pro-inflammatory responses in microglia. However, the role of AhR in the astrocytic immune responses and its subsequent effects on microglial activation and neurotoxicity remain unclear. In this study, we used LPS-induced neuroinflammation in rat cortical glia-neuron (GN) mix cultures, which increased the expression of tumor necrosis factor-α and interleukin-6 and microglial activation. These proinflammatory responses were attenuated by a specific AhR agonist 6-formylindolo [3,2-b] carbazole (FICZ), but not by the AhR antagonist CH223191. CH223191, which inhibits LPS- and FICZ-induced AhR activation, enhanced neurotoxicity induced by LPS–glutamate co-treatment in GN mix cultures. Furthermore, inhibition of AhR expression and activation enhanced LPS-induced proinflammatory responses, and LPS-induced AhR activation was abrogated by the inhibition of IDO1 expression in astrocytes. Notably, AhR knockdown inhibited the anti-inflammatory effects of KYN while enhancing LPS-induced IDO1 expression in astrocytes, suggesting that AhR mediates the anti-inflammatory effect of KYN and the negative feedback regulation of IDO1 expression. Finally, we examined the role of astrocytic AhR in inflammatory astrogliosis-induced neurotoxicity by treating primary cortical neurons with LPS-treated astrocyte–conditioned medium (ACM). The results revealed that ACM derived from siAhR-transfected astrocytes increased neurotoxicity. In conclusion, inflammation-activated AhR mediates the anti-inflammatory effects and negative feedback regulation of the IDO1/KYN pathway in astrocytes, thereby dampening inflammatory astrogliosis-induced neurotoxicity.
Burden and Associated Factors of Tuberculosis Among Household Contacts of Sputum Positive Tuberculosis Patients of Aligarh
Authors: Jude Simon , Abedi Ali J. , Mehnaz Saira , Shameem Mohammad 
Published: January 2025

Background:
Engaging patients in healthcare for diagnosis and treatment through active case-finding, which is initiated by healthcare providers, involves methodically searching for tuberculosis in individuals who may not seek medical attention otherwise. Active case finding provides a promising opportunity to identify additional undetected cases of tuberculosis within the community. The current study aimed at evaluating household contact tracing of Tuberculosis among the household contacts of pulmonary TB cases who were recently diagnosed, as well as to identify risk factors in both household contacts and index cases that contribute to the transmission of TB within households.

Materials and Method:
This cross-sectional study, which was conducted within the community, focused on the household contacts of recently diagnosed patients of Pulmonary Tuberculosis (TB) who were confirmed through microbiological testing. These patients were registered at Tuberculosis Units (TUs) of JNMC and Jawan of Aligarh district, West U.P. The investigator conducted visits to each household and met with both the index case and their corresponding household contacts to establish rapport and gather necessary information.

Results:
Within this investigation, a total of 103 individuals who tested positive for sputum smear were identified as index cases, alongside 405 household contacts of these index cases. The predominant symptom observed in household contacts who tested positive during the screening process was a cough, with fever following closely behind. Among the 405 household contacts examined, 54 individuals (13.3%) exhibited symptoms associated with Tuberculosis. Further investigation revealed that 11 of these individuals (20.37%) tested positive for tuberculosis. The total prevalence of tuberculosis cases among household contacts was determined to be 2.72%.

Conclusion:
The present research affirms that conducting contact screening for households of active TB cases is a comparatively feasible and beneficial strategy that could result in prompt diagnosis and initiation of treatment for active TB, thereby diminishing the severity of the disease and lowering the rate of transmission. Also, it can help to improve TB-related health effects, social and economic implications, and treatment outcomes in the index cases.
Assessment of Stroke Case-fatality, Disability, Perceived Needs and Barriers for Care among First-ever Stroke Patients Attending a Tertiary Care Neuro-specialty Center in India: A Cross-sectional Study
Authors: Devyani Azad , Banandur Pradeep S. , Sukumar Gautham Melur , Kulkarni Girish Baburao , Mythirayee S. , Rathore Himani 
Published: January 2025

Background:
Stroke is a major public health and clinical challenge that results in significant mortality and disability. Stroke survivors require care and support, particularly during the crucial 3 months post-stroke when 95% of functional neurological recovery occurs. To estimate case-fatality and extent of disability, assess perceived needs, barriers, and unmet needs for care, and ascertain pathways to care post-discharge (at 3 months) among first-ever stroke patients attending a tertiary care neuro-specialty center in India.

Material and Methods:
A cross-sectional descriptive study was conducted among patients receiving care within [NIMHANS]. Patients with confirmed computed tomography (CT) scans experiencing their first-ever stroke between September 1 and October 31, 2022, were contacted between November 1, 2022, and March 31, 2023. A pre-tested semi-structured questionnaire was used to collect information. Descriptive statistics were performed using STATA version 16.

Results:
Stroke fatality among study subjects was 13.8%. Almost half (49.09%) had some form of disability, with 40% having moderate to severe disability. The majority perceived the need for follow-up visits (87%) and compliance with stroke medication (84%). Distance and transportation (60%) were cited as the main barriers to care. After discharge, the majority preferred healthcare facilities close to their homes (60%).

Conclusions:
This study emphasizes the need for stroke survivors to have follow-up and compliance with medication, along with various unmet needs such as de-addiction services, vocational training, and emotional support. A network-based multi-disciplinary approach, along with a comprehensive hub and spoke model of stroke management services, could help address these challenges and improve patient outcomes.
Evaluation of bone marrow aspirate concentrate in non-union and delayed union of fractures
Authors: Buddana Mrudhula , Surath Harshavardhan , Paladugu Lakshmi Narayana , Surath Amarnath 
Published: January 2025

ABSTRACT

Introduction:
Bone Marrow Aspirate Concentrate (BMAC) belongs to a class of materials known as Orthobiologics. When used in higher concentrations will enhance the bone healing. The aspirate is rich in mononuclear cells, of which bone marrow stem cells form an integral part, which develop into osteogenic cell lines and form bone at the site of injection. BMAC gives results similar to surgical methods of treating non-union such as bone grafting. The objective of our study is to investigate the efficacy of Bone marrow aspirate concentrate injection in delayed and nonunion of fractures, to assess the outcome as well as the complications of the procedure.

Materials and Methods:
We performed a multi Centre study by including twenty-one patients who are diagnosed with non-union and delayed union of fractures. This is a non-randomized study. Bone Marrow is aspirated from the iliac crest. Ficoll solution is used for density gradient centrifugation for isolation of mononuclear stem cells. Later the concentrate is injected into the defect site. Bone formation was evaluated by X-rays in two standard planes. Level of significance was set at P < 0.05.

Results:
The critical osseous defect reached observable union by a mean of 38 ± 1.38 weeks from the time of fracture. A distance of 5 mm or less between the fractures ends resulted in healing.

Conclusion:
Our study results indicate that the method is feasible and effective in the management of Nonunion and delayed union of fractures.
Uterine adenolipoleiomyoma: An incidentaloma – A case report with review
Authors: Mohanty Pranita , Mohapatra Ajit S. , Das Prateek 
Published: January 2025

ABSTRACT
Uterine (endometrial) adenolipoleiomyoma/adenomyolipoma (UA) is an extremely rare benign hamartomatous lesion possessing debateable histogenesis. UA comprises mature adipocytes and smooth muscle bundles and glands in different proportions and a haphazard manner. It may form a polypoidal structure/intramural/intraluminal and is mostly located in the endometrial cavity/fallopian tube or very rarely cervix. Only six cases were published so far in the literature with a single case having an aggressive course in the form of recurrence. Although extremely rare and benign in nature, sometimes, they are blamed for some heralding symptoms such as profuse vaginal bleeding and hence thought to be of mullerian origin. We report such a case of adenomyolipomatous polyp in the endometrial cavity of a 39-year-old female detected incidentally while performing endometrial biopsy for abnormal uterine bleeding that was missed in abdominopelvic ultrasonography.
A study on fasting and post-prandial lipid abnormalities in type 2 diabetes mellitus in rural areas of central Telangana, India
Authors: Kamaraju Sahasra , Reddy Nithin L. , Kumar Sukesh , Gunupati Sahithi 
Published: January 2025

ABSTRACT

Background:
Post-prandial triglyceridemia has been considered an independent cardiovascular risk factor, even more important than altered fasting triglycerides, which are influenced primarily by diet. The study aimed to investigate the fasting and post-prandial lipid profile among type 2 diabetes mellitus (T2DM) patients in rural communities considering their different dietary patterns.

Patients and Methods:
Fasting and post-prandial lipid profile were done among 100 T2DM patients from a rural area in central Telangana. Fasting and post-prandial total cholesterol, triglycerides, HDL, LDL, and LDL were compared. Correlations between HbA1c and post-prandial lipid parameters and also between fasting and post-prandial lipid parameters were studied.

Results:
The mean age of the subjects was 48.17 ± 9.6 years, whereas the mean HBA1c was 9% ± 2.12%. The mean post-prandial triglycerides were significantly elevated in comparison with fasting (202 ± 101.72 vs. 161.6 ± 83.91; P < 0.0001). The mean post-prandial total cholesterol was also elevated modestly (181.8 ± 43.79 vs. 174.5 ± 36.51; P = 0.0004). There was a non-significant very weak positive correlation between HBA1c and post-prandial TGL and TC; ((r = 0.17) and (r = 0.05); P = 0.10 and P = 0.60, respectively). There was a significant positive correlation between fasting and post-prandial TC, LDL, TGL, and HDL ((r = 0.88), (r = 0.81), (r = 0.79) and (r = 0.73); (P < 0.001)).

Conclusions:
The current study found that post-prandial triglycerides were significantly elevated in comparison with fasting triglycerides. There was a very strong positive correlation between fasting and post-prandial total cholesterol, triglyceride, HDL, LDL, and VLDL.
A rare case report of pregnant women with Hodgkins lymphoma
Authors: Charishma Kobaku , Devi G. Prameela , Dedeepya Kobaku 
Published: January 2025

ABSTRACT

Introduction:
The simultaneous occurrence of cancer and pregnancy is an uncommon medical scenario and can pose a diagnostic and treatment challenge. Of malignancies diagnosed during pregnancy, hematologic malignancies rank second in the most prevalent neoplasms, after breast cancer, with Hodgkins Lymphomas (HL) and Non-Hodgkins Lymphomas (NHL) comprising nearly 6% and 5%, respectively.

Case Presentation:
A 28-year-old- female, Primigravidae with 39 weeks of gestational age with Hodgkins Lymphoma came to antenatal OPD at Government Maternity Hospital, Tirupati for regular antenatal checkups. Initially, in 2012, she had a history of neck swelling. On biopsy, it was diagnosed as tubercular lymphadenitis. However, because of poor patient compliance, she discontinued the treatment. Later on, the swelling gradually increased in size. On biopsy, it was diagnosed as Hodgkins Lymphoma. She had taken 16 cycles of chemotherapy with an ABVD (doxorubicin hydrochloride (Adriamycin), bleomycin sulfate, vinblastine sulfate, and dacarbazine) regimen. Radiological examination was performed with an Ultrasound neck revealed necrotic lymph nodes in bilateral level-V.

Conclusion:
Lymphoma is a rare diagnosis in pregnancy. Immunohistochemical markers provide prognostic stratification, and together with other clinical factors can outline the risk profile for certain groups of patients more accurately. Therefore, immunohistochemical evaluations should be considered in all cases.

Key messages: Immunohistochemical markers provide prognostic stratification, and together with other clinical factors can outline the risk profile for certain groups. Studies suggest that HL in pregnancy shows promising results with ABVD as a regimen of choice if multi-agent chemo is required. A broad multidisciplinary team-based approach is vital for improved patient outcomes.
Diagnostic accuracy of position of impacted mandibular third molar on CBCT with panoramic radiography
Authors: Rai Shalu , Misra Deepankar , Misra Akansha , Dhawan Ayush , Gupta Pulkit , Solanki Shagun 
Published: January 2025

ABSTRACT

Objective:
This study was conducted to evaluate the relationship between impacted mandibular third molar (IMTM) root and inferior alveolar nerve (IAN) as visualized on Orthopantomograph (OPG). Besides determining the need of Cone Beam Computed Tomography (CBCT) imaging, it also assesses the risk of IAN damage during surgical removal of this tooth.

Method:
A total of 100 patients underwent OPG and CBCT imaging as preoperative radiographic evaluation before extraction were included in the study. On panoramic radiographs, radiographic predictor signs of corticalization for the proximity and involvement between the IMTM and IAN and CBCT for presence or absence of corticalization and position of IAN with respect to IMTM were recorded and correlated. Chi-square test was used for statistical analysis.

Results:
Highly significant association was found between radiographic signs of Rood and Shehab such as “Darkening of root” and “Deflection of canal” and significant association was found between “Interruption of white line” and “Narrowing of canal” on OPG and presence of corticalization between IMTM root and IAN canal on CBCT. Highly significant association was found between these signs on OPG with position of IAN on CBCT such as “Darkening of Root” with “Lingual” position and “Interruption of white line” with “Interradicular” position, whereas significant association was found between “Narrowing of canal” with “Lingual” position of IAN on CBCT.

Conclusions:
Radiological evaluation with OPG alone may lead to inadequate assessments prior to surgical removal of IMTM because of its proximity with IAN and risk of neurosensory complication.