bluuebunny/crossref_metadata_2025_split huggingface dataset:
Using asynchronous programming to improve computer simulation performance in energy systems
Authors: Zhulkovskyi Oleg , Zhulkovska Inna , Kurliak Petro , Sadovoi Oleksandr , Ulianovska Yuliia , Vokhmianin Hlib 
Published: January 2025

Due to the progressing complexity of modern energy systems, the need to forecast energy consumption and generation, optimise processes and develop new technologies in the energy sector, analyse scenarios for the development of energy systems and elaborate a strategy for their development, modelling and simulation is of particular relevance in this industry. The growing need to improve the productivity of computer simulation in the energy industry is effectively addressed by utilising modern computer architectures and advanced software tools that provide acceleration for computationally intensive tasks. Research presented in this paper focuses on enhancing the performance of computationally intensive algorithms using the Thomas algorithm by employing modern asynchronous programming techniques. The work implements classical and develops and implements asynchronous computational algorithms of the sweep method with subsequent assessment of the time and efficiency of their execution for the order of systems of linear equations (SLAEs) up to 5 × 107. The program code was developed using Microsoft Visual Studio C++ and the standard template for asynchronous programming. The numerical experiments showed the possibility of increasing of the implementation speed of the asynchronous algorithm by 1.87–2.91 times. Research results correspond with the literature data and the results previously obtained by the authors in similar studies using alternative parallel programming software. In general, the results of this study determine the potential for further improvement and development of methods and technologies for parallel implementation of computational tasks using the Tridiagonal Matrix Algorithm. These approaches can be extended to developing various computer models of energy processes and systems based on the solution of SLAEs with tridiagonal matrices on computers with multiprocessor or multi-core architectures.
ASQAD MUXTORNING “TUNDALIKLAR”DA MUALLIF USLUBI VA MAHORATI
Authors: Odiljon qizi Nishonova Shohsanam 
Published: January 2025

Bugungi kunda internet rivojlangani sayin, bosma nashrlarni teraji sezilarli darajada tushib bormoqda. Bu borada shoir-yozuvchilarning ijodini, muharririlik mahoratini o‘rganish, ijod labaratoriyasini tadqiq qilib, yangi ilmiy xulolsalar berish har qachongidan muhim ahamiyat kasb etadi. Ayniqsa, Asqad Muxtor publitsistikasi ko‘lami ilmiy ish uchun munosib asos desak mubolag‘a bo‘lmaydi.
Publitsistik asarlarini mazkur yo‘nalishda tahlil etishda jurnalistikada mavzu, sarlavha tanlash mahorati, undagi g‘oya, ijtimoiy obraz topish kabi nazariy savollarga yechim topishda xizmat qiladi. Shu boisdan ham milliy jurnalistikamizda yaqin o‘tmishda ijod qilgan Asqad Muxtor kabi so‘z kishilarining mumtoz yo‘llarini o‘rganish davr talabi hisoblanadi. Xususan, mazkur tadqiqotimizda Asqad Muxtor ijodining bir qismi hisoblangan publitsistikasiga kasb nuqtayi nazardan yondashuvimiz ham dolzarb masalalardan biridir.
Análisis del procedimiento de Adecuación de Operaciones y sus derivados en su aplicación en el sector minero del Perú
Authors: Oscar André Álvarez Salvador 
Published: January 2025

Este artículo tiene como objetivo realizar un análisis del procedimiento de Adecuación de Operaciones y sus derivados en su aplicación en el sector minero del Perú; como metodología se basa en la revisión documentaria emitida por el Ministerio de Energía y Minas (MINEM) y entidades públicas encargadas de la gestión de la Adecuación de Operaciones; y como resultado se presenta la estrategia general del procedimiento así como la cantidad de acogimiento a este procedimiento extraordinario dado por la autoridad minera y algunos resultados con extensiones o derivados de este procedimiento, dando lugar a conclusiones donde es posible advertir que se trata de una medida favorable para viabilizar la regularización de componentes mineros a la adecuación ambiental, que puede permanecer en el tiempo para aliviar, entre otras, las medidas administrativas y correctivas impuestas por las autoridades fiscalizadoras como OEFA y OSINERGMIN en el Perú
تأثير تمرينات خاصة بأسلوب الهيبوكسيك في تطوير بعض المتغي ارت الفسيولوجية والمستوى الرقمي لسباحة ٥۰ متر فراشة فئة الشباب
Authors: احمد خلود عبد الوهاب 
Published: January 2025

يحتوي علم التدريب الرياضي على العدید من الفروع التي حاول الباحث كشف حقائقها بما يخدم المتدربين والوصول بهمإلى انجح الطرائق وأكثرها مالئمة لقابليتهم، فظهرت طرائق وأساليب جدیدة للتدريب الرياضي ومن هذە الطرائق طريقة التدريب بنقص األوكسجين (الهيبوكسيك-hypoxic (وقد ظهر االهتمام بأسلوب التدريب مع التحكم في التنفس (training hypoxic(، إذ عمد العدید من الباحثين والمتخصصين بد ارسة هذە الطريقة وخاصة في السباحة وألعاب القوى، إذ تعتمد هذە التدريبات على عدم استخدام النظاماألكسجينى بغرض تطوير مختلف الصفات الفسيولوجية لدى الالعبين مما یوضح أهمية مثل هذا النوع من التدريبات في االرتقاء بمستوى األداء الرياضي وعلى ذلك فقد وجد الباحث إن سباقات ٥۰ متر فراشة من سباقات المسافات القصيرة التي تعتمد على عامل السرعة وقدرة السباح على إنتاج الطاقة الالهوائية والتي هي متطلبات األداء في تلك السباقات، ويعد التدريب مع نقص األكسجين (الهيبوكسيك) من أهم األساليب التدريبية التي تستخدم لتحقيق هذا المتطلب .وهدف البحث الى: اعداد تمرينات باسلوب تدريب الهيبوكسيك لسباحي ٥۰ متر فراشة فئة الشباب، فضال عن التعر ف على تأثير تمرينات باسلوب التدريب الهيبوكسيك في تطوير بعض القدرات الفسيولوجية وسرعة االداء لسباحي ٥۰ متر فراشة. بينما فروض البحث كانت:هنالك فروق ذات داللة معنوية بين نتائج القياس القبلي والبعدي للمتغي ارت قيد الد ارسة لدى اف ارد المجموعة الضابطة ولصالح نتائجالقياس البعدي. و هنالك فروق ذات داللة معنوية بين نتائج القياس القبلي والبعدي للمتغي ارت قيد الد ارسة لدى اف ارد المجموعة التجريبية ولصالح نتائج القياس البعدي. هنالك فروق ذات داللة معنوية بين نتائج القياس البعدي للمتغي ارت قيد الد ارسة لدى اف ارد المجموعتين(الضابطة والتجريبية) ولصالح نتائج المجموعة التجريبية.واستخدم الباحث المنهج التجريبي باستخدام المجموعات المتكافئة (لمجموعتين تجريبية وضابطة) لمالءمته لطبيعة البحث. إذ تم تحدید مجتمع البحث من سباحي ٥۰ متر فراشة المنتمين لنادي المسيب الرياضي للموسم .۲۰۱۹/۲۰۱۸ وتم اختيار عينة البحث بالطريقة العشوائية من إجمالي مجتمع البحث لشباب أعضاء فريق سباحة ٥۰ متر فراشة ومن اهم االستنتاجات التي خرج بها الباحث هي وجود فروق ذات دالة إحصائيا لصالح القياسات البعدية للمجموعة التجريبية في المتغي ارت الفسيولوجية قيد الد ارسة وزمن أداء سباحة ٥۰ متر فراشة
تأثير التدريبات البالستية في بعض المتغيرات البيوكينماتيكية والانجاز بفعالية ركض 800 متر
Authors: علي احمد فاضل , سلمان داؤد سليمان 
Published: January 2025

تعد التدريبات البالستية من التدريبات الحديثة لألعاب القوى والغرض منها التغلــــــــب على نقص الســـــرعة الناتجة من التــــــــدريب التقليدي بألا ثقال، ويسمى أيـــــــضا تدريب المقاومة الباليستية وهو تمــــــرينات معينـــــة يشمل تدريبات (رفع أثقال خفيفة الوزن نسبيا وبسرعات عاليــــــة، جاكيت أثقال، كيتر أثقال وغيرها). يهدف البحث إعداد منهج تدريبيي بأسلوب التدريب الباليستي للتعرف على تأثير أسلوب التدريب الباليستي في بعض المتغيرات البدنية و البيوكينماتيكية وانجاز ركض 800 متر . اما فرضا البحث فهناك فروق ذات دلالة إحصـــــائية بين نتائج الاختبارات القبلية والبعدية لبعض المتغيرات البيوكينماتيكية والصفات البدنية والانجاز لإفراد عينة البحث ولصالح الاختبارات البعدية هناك فروق ذات دلالة إحصائية بين نتائج الاختبارات القبلية والبعدية لبعض الصفات البدنية والانجاز لإفراد عينة البحث والصالح الاختبارات البعديةواستخدم الباحث المنهج التجريبي إذ يقوم على أساس التعامل المباشر والواقعي مع الظواهر المختلفة، ويقوم على ركيزتين أساسيتين هما الملاحظة والتجربة بأنواعها والذي يعد أنسب منهج يمكن اٌستخدامه لحل مشكلة البحث بأسلوب المجموعة الواحدة، أما مجتمع البحث فتمثل من عدائي منتخب محافظة ميسان في ركض 800 متر، والبالغ عددهم (12) عداءً إذ اختيرت العينة بالطريقة العمدية من اللاعبين الشباب وكان عددهم (6) عداء من هذا المجتمع وقد بلغت النسبة المئوية لعينة البحث المختارة من مجتمع البحث الكلي (50%) . استخدم الباحث برامجspss والوسط الحسابي والانحراف المعياري ومعامل الاختلاف النسبي لغرض الحصول على النتائج الإحصائية، لذا ارتأى الباحثان دراسة هذه المشكلة من خلال إيجاد تمرينات بأسلوب الباليستي بشكل مقنن وباستخدام الوسائل العلمية والتي يمكن من خلالها تطــوير بعض المتغيرات البيوكينماتيكية والصفات البدنية والانجاز لدى عدائي ركض 800 متر .من اجل الارتقاء بمستوى هذه الفعالية .
L’évolution du mouvement parasportif français : les enjeux et les défis
Authors: Duquesne Valentine 
Published: January 2025

Le mouvement parasportif français s’est construit de manière atypique, avec une structuration hybride entre le milieu sportif spécifique et le milieu sportif ordinaire ; structuration qui continue à évoluer. Outre les deux fédérations spécifiques, de plus en plus de fédérations ordinaires organisent la pratique parasportive. Ces transformations organisationnelles du parasport en France entraînent des évolutions institutionnelles, notamment concernant le Comité Paralympique et Sportif Français (CPSF). Ce dernier accompagne les fédérations spécifiques comme ordinaires ayant en charge l’organisation d’une ou plusieurs disciplines parasportives. Le CPSF met en place des actions transversales au sein du mouvement sportif et parasportif, de la société civile, associative, etc., afin de participer à l’amélioration de la pratique parasportive. Une autre finalité est aussi de faire évoluer le regard de la société sur le handicap. Les défis et les enjeux sont donc nombreux, et le CPSF s’appuiera sur tous les acteurs et évènements, dont les Jeux Paralympiques de Paris pour faire connaître le parasport.
Design, Construction, and Evaluation of a Passive Solar Dryer for Sustainable Food Preservation
Authors: Koleleni Yusuf Ismail 
Published: January 2025

Solar drying is a very old but continuously explored technology so that everyone can use to dry food products from meat, vegetables, cereals and the dairy products. However, over the time with increased pollution to both the air and water, the sun drying has been deteriorating. Solar drying provides a safe and reliable environment for the quality of the dried products and its preservative duration. This study, design and construction of the solar drier device has been done for the purpose of drying a variety of food products. The principle of the dryer allows lighter hot air to rises up the altitude and cool the surface. In the raising process warm air comes in contact with the food slices and draws the moisture from it. The repeated cycle of this process makes it a very healthy, low cost long-term drying mechanism. In the thermodynamics terms the sun’s power or heat is used to dry up the moisture content of the fruits or vegetables. The construction materials were wood, polyurethane glass, mild steel metal sheet and the trays. The optimum temperature of the dryer was 750C with a corresponding ambient temperature of 280 C. The rapid rate of drying in the dryer reveals its ability to dry food items reasonably rapidly to a safe moisture. The capital cost involved in the construction of solar drier is much lower compared to that of a mechanical drier. Also from the test carried out, the simple and inexpensive solar drier was designed and constructed using locally sourced materials. The temperature inside the drier was found to be about three times than that of the outside atmospheric temperature. As per our experiment the maximum peak temperature inside the drying chambers was 750C during the mid-day (1.00pm) and an average of 570C in a fully sunny day (from 10:00am to 5:00pm). In seven (7) hours continuous drying in one full sunny day under the same climatic condition and in the same time the solar drier can remove maximum moisture contents from the food contents inside the drier for low moisture content food products. Experimental observation shows that the solar drier can be used as an alternative in case of food preservation and the efficiency is also acceptable. The people can make it on their homes especially in the developing countries where the energy demand is higher.
Cost of Exempting Sole Orphan Drugs From Medicare Negotiation
Authors: Vogel Matthew , Zhao Olivia , Feldman William B. , Chandra Amitabh , Kesselheim Aaron S. , Rome Benjamin N. 
Published: November 2023

ImportanceThe Inflation Reduction Act (IRA) requires Medicare to negotiate prices for some high-spending drugs but exempts drugs approved solely for the treatment of a single rare disease.ObjectiveTo estimate Medicare spending and global revenues for drugs that might have been exempt from negotiation from 2012 to 2021.Design, Setting, and ParticipantsThis cross-sectional study analyzed drugs that met the IRA threshold for price negotiation (Medicare spending &amp;gt;$200 million/y) in any year from 2012 to 2021 and had an Orphan Drug Act designation. We stratified drugs into 4 mutually exclusive categories: approved for a single rare disease (sole orphan), approved for multiple rare diseases (multiorphan), initially approved for a rare disease and subsequently approved for a nonrare disease (orphan first), and initially approved for a nonrare disease and subsequently approved for a rare disease (non–orphan first).OutcomesThe primary outcomes were the number of sole orphan drugs, estimated Medicare spending on those drugs from 2012 to 2021, and global revenue since launch.ResultsAmong 282 drugs, 95 (34%) were approved to treat at least 1 rare disease, including 25 sole orphan drugs (26%), 20 multiorphan drugs (21%), 13 orphan first drugs (14%), and 37 non–orphan first drugs (39%). From 2012 to 2021, Medicare spending on sole orphan drugs increased from $3.4 billion to $10.0 billion. Each year, a median (IQR) of $2.5 ($1.9-$2.6) billion in Medicare spending would have been excluded from price negotiation because of the sole orphan exemption. The cumulative global revenue of the median (IQR) sole orphan drug was $11 ($6.6-$19.2) billion.Conclusions and RelevanceThe sole orphan exemption will exclude billions of dollars of Medicare drug spending from price negotiation. The high level of global revenues achieved by these drugs, however, suggests that special exemption is unnecessary for them to achieve financial success. Congress could consider removing the sole orphan exemption to obtain additional savings for patients and taxpayers and to eliminate any potential disincentive for developing additional indications for these drugs.
Ultrathin WOx Nanoribbons with Moderate ROS Clearance and Antibacterial Abilities Efficiently Induce M2 Macrophage Polarization for Diabetic Bone Defect Repair
Authors: Wang Jiechen , Zhang Chenguang , Zhang Wenshu , Liu Wenwen , Guo Yaru , Dang Pengrui , Wei Ling , Zhao Han , Deng Xuliang , Guo Shaojun , Chen Lili 
Published: November 2023

AbstractThe repair of bone defects in diabetes remains a major challenge in the field of biomedicine because of the disturbance of bone immune homeostasis and the susceptibility of exposed wounds to bacterial infection. Clinically, immunoregulation by removing excessive reactive oxygen species (ROS) effectively promotes diabetic bone defect repair. However, aggressive ROS clearance can disrupt ROS homeostasis, making ROS‐mediated polarization of M2 macrophages in the process of tissue healing of diabetes be difficult. Herein, an ultrathin defective tungsten oxide (WOx) nanoribbon with high oxygen vacancies to simultaneously achieve moderate scavenging of ROS and high broad‐spectrum photothermal antibacterial activity to promote diabetic bone defect repair is reported. It is demonstrated that the moderate ROS clearance ability of WOx nanoribbons can remodel metabolic patterns for achieving 86.3% M2 macrophage induction in a high glucose microenvironment. This high induction efficiency combined with excellent photothermal antibacterial ability of WOx nanoribbons markedly alleviated the inflammatory reaction and efficiently facilitated the repair of bone defects infected with methicillin‐resistant Staphylococcus aureus (S. aureus) in C57BLKS/J (BKS)‐diabetic (BKS‐db) mice.
Significant Efficiency and Stability Enhancement of Flexible Perovskite Solar Cells Combining with Multifunctional Effects of a Natural Spice
Authors: Yi Zijun , Zhang Wenguang , Xiong Yuchen , Xiao Bo , Jiang Qinghui , Luo Yubo , Li Xin , Yang Junyou 
Published: November 2023

AbstractThe numerous defect‐induced non‐radiative recombination losses and residual stress in the preparation of perovskite film greatly hinder the further improvement of the efficiency and stability of flexible perovskite solar cells (PSCs). Here, a natural spice 7‐amino‐4‐(trifluoromethyl)‐2‐benzopyrone (ATB) containing amino (─NH2), carbonyl (─C═O), and trifluoromethyl (─CF3) functional groups is introduced into the perovskite precursor solution, thereby preparing high‐quality perovskite film with low defect density. It is revealed that the utilization of ATB is beneficial to comprehensively passivate the defects and release the residual stress of perovskite film through the synergistic effect of functional groups, thereby improving the crystallinity and enhancing the carrier lifetime of perovskite film. Moreover, the introduction of ATB contributes to an improved energy levels alignment between the perovskite and adjacent layers, which facilitates fast carrier transport and suppresses the recombination loss in the flexible PSCs. Combined with the multifunctional effects of ATB, the target flexible and rigid PSCs with ATB modification yield remarkable photoelectric conversion efficiency (PCE) of 21.08% and 23.79%, respectively. More importantly, the ATB‐modified flexible device exhibits outstanding stability and retains 87.3% and 91.6% of the original efficiency after aging for 3000 h at 50 ± 5 relative humidity and 5000 bending cycles, respectively.
Core–Shell Perovskite Quantum Dots for Highly Selective Room‐Temperature Spin Light‐Emitting Diodes
Authors: Jang Gyumin , Jo Dae‐Yeon , Ma Sunihl , Lee Junwoo , Son Jaehyun , Lee Chan Uk , Jeong Wooyong , Yang Seongyeon , Park Jeong Hyun , Yang Heesun , Moon Jooho 
Published: November 2023

AbstractCircularly polarized light (CPL) is a crucial light source with a wide variety of potential applications such as magnetic recording, and 3D display. Here, core–shell heterostructured perovskite quantum dots (QDs) for room‐temperature spin‐polarized light‐emitting diodes (spin‐LEDs) are developed. Specifically, a 2D chiral perovskite shell is deposited onto the achiral 3D inorganic perovskite (CsPbBr3) core. Owing to the chiral‐induced spin selectivity effect, the spin state of the injected charge carriers is biased when they are transmitted through the 2D chiral shell. The spin‐controlled carriers then radiatively recombine inside the CsPbBr3 emissive core, resulting in CPL emission. It is demonstrated that the (R)‐ and (S)‐1‐(2‐(naphthyl)ethylamine) (R‐/S‐NEA) 2D chiral cations enhance the spin polarization degree due to their strong chiroptical properties. Systematical defect analyses confirm that 2D chiral cations (i.e., R‐/S‐NEA) successfully passivate halide vacancies at the surface of the CsPbBr3 QDs, thereby attaining a high photoluminescence quantum yield of 78%. Moreover, the spin‐LEDs prepared with core–shell QDs achieve a maximum external quantum efficiency of 5.47% and circularly polarized electroluminescence with a polarization degree (PCP‐EL) of 12% at room temperature. Finally, various patterns fabricated by inkjet printing the core–shell QDs emit strong CPL, highlighting their potential as an emitter for next‐generation displays.
Intestine‐Targeted Explosive Hydrogel Microsphere Promotes Uric Acid Excretion for Gout Therapy
Authors: Tang Yunkai , Du Yawei , Ye Junna , Deng Lianfu , Cui Wenguo 
Published: November 2023

AbstractUric acid metabolism disorder triggers metabolic diseases, especially gout. However, increasing uric acid excretion remains a challenge. Here, an accelerative uric acid excretion pathway via an oral intestine‐explosive hydrogel microsphere merely containing uricase and dopamine is reported. After oral administration, uricase is exposed and immobilized on intestinal mucosa along with an in situ dopamine polymerization via a cascade reaction triggered by the intestinal specific environment. By this means, trace amount of uricase is required to in situ up‐regulate uric acid transporter proteins of intestinal epithelial cells, causing accelerated intestinal uric acid excretion. From in vitro data, the uric acid in fecal samples from gout patients could be significantly reduced by up to 37% by the mimic mucosa‐immobilized uricase on the isolated porcine tissues. Both hyperuricemia and acute gouty arthritis in vivo mouse models confirm the uric acid excretion efficacy of intestine‐explosive hydrogel microspheres. Fecal uric acid excretion is increased around 30% and blood uric acid is reduced more than 70%. In addition, 16S ribosomal RNA sequencing showed that the microspheres optimized intestinal flora composition as well. In conclusion, a unique pathway via the intestine in situ regulation to realize an efficient uric acid intestinal excretion for gout therapy is developed.
Bioinspired Hard–Soft Composite Scaffold with Excellent Lubrication and Osteogenic Properties for the Treatment of Osteochondral Defect
Authors: Hu Keming , Ma Qi , Guo Weicheng , Zhao Weiwei , Zhao Yanran , Cai Xu , Zhang Hongyu 
Published: November 2023

AbstractNatural articular cartilage is a typical self‐healing and superlubrication system capable of maintaining extremely low friction under physiological loadings. Cartilage wear and accidental trauma can cause irreversible defects to cartilage and subchondral bone with a significant decrease in intra‐articular lubrication, leading to the development of severe osteoarthritis and osteochondral defect. To address the important clinical problem of osteochondral defect, a bioinspired hard–soft (PEEK‐lubrication hydrogel) composite scaffold is designed and developed. The polymerization of polyethylene glycol diacrylamide (PEGDAA) and 2‐methacryloyloxyethyl phosphorylcholine (MPC) on polyetheretherketone (PEEK) substrate is achieved by UV initiation to form a strong interfacial bonding, and nano‐hydroxyapatite is deposited on porous PEEK substrate via polydopamine coating to improve osteogenic capability. Accordingly, the composite scaffold is successfully developed with lubrication and osteogenic activity. The tribological tests show that the lubrication performance of the composite scaffold is based on the hydration lubrication mechanism of the upper hydrogel layer, and the in vitro and in vivo experiments demonstrate that the composite scaffold is endowed with excellent biocompatibility and bioactivity. In conclusion, the bioinspired strategy for preparing a hard–soft composite scaffold shows a promising way in the treatment of osteochondral defect and provided a guideline for designing functional PEEK‐based biomaterials in tissue engineering scaffolds.
Transfer‐Free Creation of Hierarchical Wrinkle Patterns for Stretchable and Compliant Strain and Contact Sensing
Authors: Cai Catherine Jiayi , Kalairaj Manivannan Sivaperuman , Huang Hui , Chen Po‐Yen , Ren Hongliang 
Published: November 2023

Higher order hierarchical wrinkle patterns may extend the functionalities and enable new capabilities in the devices created, but current transfer‐based methods are often complex and tedious. This work develops a transfer‐free method to generate hierarchical wrinkle patterns in MXene thin films via controlled deflation of a latex balloon substrate by exploiting its thermal‐elastic properties. This work generates four different wrinkle patterns with varying strain sensitivity: 2D (GF = 0.593), 1D1D (GF = 0.0979), 2D1D (GF = 0.0165), and 2D2D (GF = 0.545). Taking advantage of the small strain response exhibited by the 2D1D electrode, this work fabricates stretchable stain‐insensitive contact sensors where its behavior can be tuned by varying the thickness of the spacer. When the spacer is 0.16 mm thick, the sensor is observed to have a pressure sensitivity of 0.0922, 0.109, and 0.112 kPa−1 at 0%, 25% and 50% stretching states respectively at pressures of <2500 Pa. When the spacer is 0.32 mm thick, the sensor is observed to have a pressure sensitivity of 0.154, 0.185, and 0.233 kPa−1 under 0%, 25% and 50% strain respectively between the pressure range of 2900–5200 Pa.