bluuebunny/crossref_metadata_2025_split huggingface dataset:
OPTIMIZATION OF A METHOD FOR HIGH-ENERGY GRINDING OF POWDER MIXTURES OF THE Ti-Al-Nb SYSTEM IN THE PRESENCE OF STEARIC ACID AND TOLUENE
Authors: Kozhakhmetov E. A. , Mukhamedova N. M. , Miniyazov A. Zh. , Urkunbay A. S. 
Published: October 2023

In this work, the influence of process control agents on the morphology and structural-phase state of powder mixtures of the Ti-Al-Nb system was studied. To improve the technique for grinding powder mixtures of the Ti-Al-Nb system in a planetary ball mill, two types of powders were prepared with the addition of process control agents based on stearic acid and liquid toluene. The process of grinding the compositions with the addition of agents was carried out at 550 rpm/m for 30, 60, 120, 180 minutes.During the studies, it was found that the evolution of particle morphologies using stearic acid and liquid toluene was similar. The effect of the agent as a process regulator of stearic acid on the evolution of powder morphology was greater than that of liquid toluene, since it inhibited the cold welding process of powders more effectively. During high-energy grinding using toluene for 120 and 180 minutes, undesirable carbide phases are formed.
Emergent Certainty and the Limits of Uncertainty: Expressing Certainty in a Gestalt Paradigm
Authors: O’Malley Chris 
Published: October 2023

ABSTRACTThe expression of certainty within a Gestalt clinical praxis has been unhelpfully discouraged. Expressing certainty has been aligned with abuses of power, while maintaining uncertainty has become a shibboleth of Gestalt thinking. This is theoretically unsound and potentially therapist-privileging, contributing to an amoral practitioner neutrality rather than an implicated, ethical responsibility. From a specific clinical encounter in which certainty is expressed, a basis is built to support how a Gestalt access to certainty might be understood and achieved with regard to knowledge and truth, beyond irrelevant imperatives of being right, or of implying permanence. Certainty is conceptualized to befit Gestalt’s field-theoretical paradigm, and the key theory of creative indifference is employed to critique the unipolar prioritizing of uncertainty. With support from Wittgenstein, it is argued that inhabiting certainty can demonstrate commitment and be an authentic manifestation of responsibility in a field paradigm, contributing to an ethical practice and a successful clinical outcome.
Creepiness and the Uncanny
Authors: Kjeldgaard-Christiansen Jens , Clasen Mathias 
Published: October 2023

ABSTRACT
To feel nervously and apprehensively “creeped out” is a familiar emotional state, but its cause—what makes something or someone “creepy”—is poorly understood. A recent evolutionary account of creepiness suggests that the emotion arises from a perceived “ambiguity about the presence of threat” (McAndrew and Koehnke 10). However, not all ambiguous threats are perceived as creepy. This article argues that specifically creepy threats arise from disrupted mentalization, by which is meant difficulties in apprehending the mind of another being in such a way as to make that being seem threateningly unpredictable. The authors propose that this explanation of creepiness also explains “the uncanny,” a concept that is closely related to creepiness and to which a much older and larger research literature attaches. Finally, it is suggested that the present account can make sense of some iconically creepy figures of horror fictions, including zombies, ghosts, and ominously unhuman children.
John Ruskin on Reading
Authors: Woudenberg René Van 
Published: October 2023

AbstractVictorians read a lot, and they reflected on reading: Why read? What to read? Reading to what goal? After some stage setting, this article discusses four of John Ruskin’s thoughts on reading as expounded in Sesame and Lilies (1865) and that have never received much attention. (1) There are two species of books, “books of the hour” and “books of all time.” (2) The selection of which books to read is an ethical matter. (3) The norm for reading that readers should aim to comply with is the author’s meaning. (4) Readers should love the authors they are reading in order to understand them truly. This article discusses these claims and argues for a qualified endorsement of (1) in favor of (2), argues that (3) constitutes the commonsense view of reading, and defends it against various criticisms. The article finally argues against (4).
A competitividade sistêmica do agronegócio sucroalcooleiro: estratégias internas e fatores externos
Authors: Borges Ana Claudia Giannini , Costa Vera Mariza Henriques de Miranda 
Published: October 2023

Constituem objetivos do presente trabalho: a) caracterizar a evolução recente do agronegócio sucroalcooleiro, destacando as ações efetivadas visando à competitividade do setor e de empresas que o compõem, bem como alterações que interferem em sua competitividade sistêmica, relacionadas aos ambientes interno e externo das empresas; b) avaliar o suporte financeiro do BNDES (banco nacional de desenvolvimento econômico e social) ao setor como novo padrão de atuação do estado, após a desregulamentação do setor sucroalcooleiro, ocorrida a partir da década de 1990; c) evidenciar a relevância da atuação do estado sobre o agronegócio sucroalcooleiro para viabilizar ações inovadoras, favorecendo sua competitividade sistêmica. O trabalho foi estruturado a partir de avaliação de literatura referente à caracterização, aos limites e ao âmbito da competitividade; e de dados, informações e avaliações sobre a evolução do agronegócio sucroalcooleiro em literatura especializada e junto a instituições e organismos que dispõem de conhecimento desse setor. Pôde-se concluir que a participação do estado no agronegócio sucroalcooleiro mantém-se relevante, mesmo após o processo de desregulamentação; realizada, no período recente, por meio de financiamento por parte do BNDES, a atuação do estado tem sido significativa para a competitividade sistêmica da atividade sucroalcooleira brasileira.
Incorporación de símbolos tridimensionales en planos táctiles para la mejora de su usabilidad
Authors:   , Gual Ortí Jaume 
Published: October 2023

Objetivo: El estudio que aquí se expone tiene como objetivo principal la mejora de la usabilidad de los planos táctiles orientados a personas con discapacidad visual.
Metodología: A partir de una metodología experimental principalmente cuantitativa como la medición de los tiempos de ejecución y errores cometidos en tareas propias del empleo de planos táctiles y, también, el uso de instrumentos como encuestas y mapas cognitivos, se han realizado una serie de cinco experimentos con usuarios de los que se ha extraído una amplio numero de datos indicadores de la eficacia y eficiencia en el uso de este tipo de dispositivos, así como de su valoración subjetiva.
Resultados: Los resultados obtenidos en estos experimentos indican una valoración positiva de los planos táctiles como instrumentos para la mejora del aprendizaje espacial por parte de usuarios con discapacidad visual, así como una mejoría en términos de usabilidad producida por el efecto de introducir determinada simbología tridimensional en planos táctiles.
Objective: The study presented here has as main objective the improvement of the usability of tactile maps oriented to people with visual disabilities.
Methodology: On basis of a quantitative experimental methodology seven experiments with users have been conducted, mesuring time on task and errors; survey have been conducted as well. A large number of data indicative of the effectiveness and efficiency of tactile maps and their subjetive rating have been obtained. In addition, cognitive maps have been used as qualitative methodology.
Results: The results of these experiments indicate a positive assessment of tactile maps as devices for improving spatial learning by visually impaired users, as well as an improvement of tactile maps, in terms of usability, by the effect of introducing three-dimensional symbology.
Optimización de las estrategias metodológicas del diseño y gestión de las actividades autónomas utilizando las tecnologías de la información y las telecomunicaciones
Authors:   , Delgado Noya Irene 
Published: October 2023

The current investigation is aimed to improve the planning, orientation, monitoring, control and evaluation of the autonomous activities which a student must realize with the support of a Virtual Learning Environment (VLE). The chosen subject for this investigation is Physics in the European University of the Atlantic (UNEATLANTICO), which is taught during the first year of Engineering Degrees: Computer Engineering, Industrial Organisation and Agro-Food Engineering.
The suggested methodology is based on a five-phase strategy:
*Planning
*Orientation
*Monitoring
*Control-evaluation
*Assessment
The activities of each phase are defined according to pedagogical and techonological aspects. A sample of the strategy's implementation was compiled during a seminar on Physics.
The novelty is to disclose the relation between the autonomous activities and its particularities in VLE. In order to corroborate the appropriateness and scientific value of the strategy, experts criterion have been applied. A Iadov Test has been performed to demonstrate the strategy applied during the seminar. On the basis of the obtained results of the methodology and techniques aforementioned, it was performed a methodological triagulation that allowed to reinforce the value of the investigation.
La presente investigación está dirigida a mejorar la planificación, orientación, seguimiento, control y evaluación de las actividades autónomas que se espera que realice el alumno con apoyo del Entorno Virtual de Enseñanza/Aprendizaje (EVE/A) en la asignatura de Física, asignatura que se imparte en la Universidad Europea del Atlántico (UNEATLANTICO) durante el primer año de las carreras de Ingeniería: Ingeniería Informática, Ingeniería de Organización Industrial e Ingeniería de las industrias Agrarias y Alimentarias. Como aporte práctico se propone una estrategia metodológica constituida por cinco etapas: - Planificación - Orientación - Seguimiento - Control-evaluación - Valoración. Las acciones de cada etapa se definen teniendo en cuenta tanto el aspecto pedagógico como el tecnológico. Como muestra de la aplicación de la estrategia se describe su implementación en un seminario de la asignatura de Física. La novedad es haber revelado las relaciones que se dan con carácter de regularidades en la gestión de las actividades autónomas y sus particularidades en los EVE/A. Para corroborar la pertinencia y el valor científico de la estrategia se empleó el criterio de expertos. Se realizó un Test de Iadov para demostrar la factibilidad de la estrategia aplicada en el seminario. A partir de los resultados obtenidos con los métodos y técnicas mencionados se realizó una triangulación metodológica que permitió reforzar el valor de la investigación
Reflections
Authors: Quain David 
Published: October 2023

In this, the third issue of the Journal in 2023, Reflections considers the return of ‘correspondence’ with a discussion between Charles Bamforth and Ricardo Fritzsche regarding Charlie’s Provocation review from earlier this year. In the last century (!), ‘correspondence’ or ‘Letter to the Editor’ was a regular feature in JIB. Rather more contemporary is the use of Google Analytics to analyse website traffic. Whilst a rich source of data, the wheat needs sorting from the chaff. The numbers are interesting and will become more so over time. In terms of visitors to https://jib.ibd.org.uk/index.php/jib, they are from 90 countries with three quarters coming from 10 countries. Continuing the ‘numbers’ theme, there are four KPIs which capture steps from submission to publication. These provide useful insights into the process and identify opportunities for improvement. These KPIs are updated with each issue of the Journal. Finally, a reminder to budding authors that the current ‘instructions to authors’ must be consulted and carefully applied to the submitted manuscript. This saves time (for everyone) and avoids the ‘desk rejection’ of manuscripts that ignore the instructions.
Métodos para redução e inativação de fatores antinutricionais em alimentos de origem vegetal: uma revisão
Authors: De Oliveira Pereira Fabiana , Rodrigues Martins Ingryd , Da Conceição Amaral Ribeiro Suezilde , Suzuki Júlio Cesar , Sarkis Peixoto Joele Maria Regina 
Published: October 2023

O consumo de produtos de origem vegetal a base de plantas tem sido proposta como uma alternativa eficiente na prevenção de doenças crônicas. No entanto, diferentes plantas produzem fatores antinutricionais, que podem apresentar efeitos negativos e/ou positivos à saúde. Diante do exposto, o presente trabalho apresenta uma revisão integrativa, onde foram estabelecidas as seguintes perguntas norteadoras: “Os antinutrientes dos alimentos de origem vegetal são avaliados na escolha de uma dieta equilibrada e saudável?” “Qual a importância de analisar seus efeitos na saúde humana? São considerados vilões ou heróis?”. A revisão integrativa foi realizada por meio do levantamento de estudos nacionais e internacionais no Portal de Periódicos da Capes, totalizando 1094 artigos científicos. Na triagem, foram filtrados 343, dos quais 127 foram classificados para a apresentação do cenário atual e das perspectivas esperadas sobre a temática elencada. Alguns compostos com ação antinutricional, tem sido considerados danosos à saúde em virtude do seu potencial de reduzir a biodisponibilidade de nutrientes essenciais. Apesar das evidências, pesquisas relatam resultados antagônicos, pois alguns destes, tornaram-se conhecidos por seus efeitos benéficos, com potenciais terapêuticos em diversas doenças crônicas. À vista disso, o consumo de compostos com fatores antinutricionais é relativo com relação às vantagens e desvantagens à saúde, que em certos casos, podem ter desde a ação terapêutica até efeitos prejudiciais, em indivíduos susceptíveis a dietas restritivas à base de plantas. Dessa forma, faz-se necessário, adotar técnicas como imersão, cozimento, fermentação, aquecimento dielétrico, extrusão e irradiação γ, para reduzir ou inativar os compostos antinutricionais a níveis seguros na ingestão de vegetais para o consumidor.
Lire les profonds dans l’oeuvre romanesque de Kossi Efoui
Authors: Tsetse Kodzo Etonam 
Published: October 2023

Cet article propose une lecture de l’oeuvre romanesque de Kossi Efoui comme récit des profonds. Il montre l’irruption matérielle des profonds (mines, métaux rares, nappes souterraines et océan Atlantique) dans les récits (notamment Solo d’un revenant et L’Ombre des choses à venir) : par la convoitise qu’ils suscitent, leur énergie et leur puissance, ils peuvent remettre en cause l’existence des communautés qui vivent à la surface, souvent dans l’ignorance des matières enfouies dans le sous-sol. Loin de déboucher systématiquement sur l’impression du désastre, la pensée des profonds mène aussi l’écrivain à une conception de l’océan Atlantique comme refuge poétique, et de la submersion comme horizon souhaitable.
Molecular and phenotypic distinctions of macrophages in tolerant and susceptible to hypoxia rats
Authors: Dzhalilova Dzhuliia , Kosyreva Anna , Lokhonina Anastasiya , Tsvetkov Ivan , Vishnyakova Polina , Makarova Olga , Fatkhudinov Timur 
Published: October 2023

Individual hypoxia tolerance is a major influence on the course and outcome of infectious and inflammatory diseases. Macrophages, which play central roles in systemic inflammatory response and other immunity reactions, are subject to functional activation orchestrated by several transcription factors including hypoxia inducible factors (HIFs). HIF-1 expression levels and the lipopolysaccharide (LPS)-induced systemic inflammatory response severity have been shown to correlate with hypoxia tolerance. Molecular and functional features of macrophages, depending on the organisms resistance to hypoxia, can determine the severity of the course of infectious and inflammatory diseases, including the systemic inflammatory response. The purpose is the comparative molecular and functional characterization of non-activated and LPS-activated bone marrow-derived macrophages under normoxia in rats with different tolerance to oxygen deprivation. Hypoxia resistance was assessed by gasping time measurement in an 11,500 m altitude-equivalent hypobaric decompression chamber. Based on the outcome, the animals were assigned to three groups termed ‘tolerant to hypoxia’ (n = 12), ‘normal’, and ‘susceptible to hypoxia’ (n = 13). The ‘normal’ group was excluded from subsequent experiments. One month after hypoxia resistance test, the blood was collected from the tail vein to isolate monocytes. Non-activated and LPS-activated macrophage cultures were investigated by PCR, flow cytometry and Western blot methods. Gene expression patterns of non-activated cultured macrophages from tolerant and susceptible to hypoxia animals differed. We observed higher expression of VEGF and CD11b and lower expression of Tnfa, Il1b and Epas1 in non-activated cultures obtained from tolerant to hypoxia animals, whereas HIF-1α mRNA and protein expression levels were similar. LPS-activated macrophage cultures derived from susceptible to hypoxia animals expressed higher levels of Hif1a and CCR7 than the tolerant group; in addition, the activation was associated with increased content of HIF-1α in cell culture medium. The observed differences indicate a specific propensity toward pro-inflammatory macrophage polarization in susceptible to hypoxia rats.
Complete chloroplast genome assembly and phylogenetic analysis of blackcurrant (Ribes nigrum), red and white currant (Ribes rubrum), and gooseberry (Ribes uva-crispa) provide new insights into the phylogeny of Grossulariaceae
Authors: Sun Xinyu , Zhan Ying , Li Songlin , Liu Yu , Fu Qiang , Quan Xin , Xiong Jinyu , Gang Huixin , Zhang Lijun , Qi Huijuan , Wang Aoxue , Huo Junwei , Qin Dong , Zhu Chenqiao 
Published: October 2023

Background
Blackcurrant (Ribes nigrum), red currant (R. rubrum), white currant (R. rubrum), and gooseberry (R. uva-crispa) belong to Grossulariaceae and are popular small-berry crops worldwide. The lack of genomic data has severely limited their systematic classification and molecular breeding.

Methods
The complete chloroplast (cp) genomes of these four taxa were assembled for the first time using MGI-DNBSEQ reads, and their genome structures, repeat elements and protein-coding genes were annotated. By genomic comparison of the present four and previous released five Ribes cp genomes, the genomic variations were identified. By phylogenetic analysis based on maximum-likelihood and Bayesian methods, the phylogeny of Grossulariaceae and the infrageneric relationships of the Ribes were revealed.

Results
The four cp genomes have lengths ranging from 157,450 to 157,802 bp and 131 shared genes. A total of 3,322 SNPs and 485 Indels were identified from the nine released Ribes cp genomes. Red currant and white currant have 100% identical cp genomes partially supporting the hypothesis that white currant (R. rubrum) is a fruit color variant of red currant (R. rubrum). The most polymorphic genic and intergenic region is ycf1 and trnT-psbD, respectively. The phylogenetic analysis demonstrated the monophyly of Grossulariaceae in Saxifragales and the paraphyletic relationship between Saxifragaceae and Grossulariaceae. Notably, the Grossularia subgenus is well nested within the Ribes subgenus and shows a paraphyletic relationship with the co-ancestor of Calobotrya and Coreosma sections, which challenges the dichotomous subclassification of the Ribes genus based on morphology (subgenus Ribes and subgenus Grossularia). These data, results, and insights lay a foundation for the phylogenetic research and breeding of Ribes species.
UV Spectrophotometric Quantification of Sudan-IV Dye in Palm Oil from Major Markets of Benin Metropolis
Authors: Asiriuwa N. U. , Akpose I. O. , Okogbenin E. A. , Imoisi O. B. , Onyia D. C. , Okunwaye T. , Gold I. L. , Obibuzor J. U. , Anemene H. 
Published: October 2023

The deficit in the supply of palm oil in Nigeria over the years has been met in part through smuggling of the product from different sources into the Nigerian market by marketers of which some of the products have been reported to be adulterated with azo dyes. The aim of this study was to detect and quantify sudan dyes in adulterated palm oil from the open market using simple and inexpensive procedures such as analytical thin layer chromatography (TLC) and Ultra violet spectrophotometric methods respectively. Seven palm oil samples from the open markets within Benin metropolis labelled as (AUC, AUC2, IK1, IK5, OLK1, ADIT, and OB) were screened for the presence of Sudan-III and Sudan-IV dyes. Four of the samples (IK1, IK5, OLK1, ADIT) were confirmed to contain Sudan-IV dye with quantities of 22.5mg/L, 21.7mg/L, 29.5mg/L, 23.8mg/L respectively. This experiment shows that the use of easy and cheap methods such as TLC and UV-spectrophotometry can be used to detect and quantify Sudan dyes in adulterated palm oil.
Diagnosis and Treatment of Bipolar Disorder
Authors: Nierenberg Andrew A. , Agustini Bruno , Köhler-Forsberg Ole , Cusin Cristina , Katz Douglas , Sylvia Louisa G. , Peters Amy , Berk Michael 
Published: October 2023

ImportanceBipolar disorder affects approximately 8 million adults in the US and approximately 40 million individuals worldwide.ObservationsBipolar disorder is characterized by recurrent episodes of depression and mania or hypomania. Bipolar depressive episodes are similar to major depressive episodes. Manic and hypomanic episodes are characterized by a distinct change in mood and behavior during discrete time periods. The age of onset is usually between 15 and 25 years, and depression is the most frequent initial presentation. Approximately 75% of symptomatic time consists of depressive episodes or symptoms. Early diagnosis and treatment are associated with a more favorable prognosis. Diagnosis and optimal treatment are often delayed by a mean of approximately 9 years following an initial depressive episode. Long-term treatment consists of mood stabilizers, such as lithium, valproate, and lamotrigine. Antipsychotic agents, such as quetiapine, aripiprazole, asenapine, lurasidone, and cariprazine, are recommended, but some are associated with weight gain. Antidepressants are not recommended as monotherapy. More than 50% of patients with bipolar disorder are not adherent to treatment. Life expectancy is reduced by approximately 12 to 14 years in people with bipolar disorder, with a 1.6-fold to 2-fold increase in cardiovascular mortality occurring a mean of 17 years earlier compared with the general population. Prevalence rates of metabolic syndrome (37%), obesity (21%), cigarette smoking (45%), and type 2 diabetes (14%) are higher among people with bipolar disorder, contributing to the risk of early mortality. The annual suicide rate is approximately 0.9% among individuals with bipolar disorder, compared with 0.014% in the general population. Approximately 15% to 20% of people with bipolar disorder die by suicide.Conclusions and RelevanceBipolar disorder affects approximately 8 million adults in the US. First-line therapy includes mood stabilizers, such as lithium, anticonvulsants, such as valproate and lamotrigine, and atypical antipsychotic drugs, such as quetiapine, aripiprazole, asenapine, lurasidone, and cariprazine.