bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification and functional analysis of ovarian lncRNAs during different egg laying periods in Taihe Black-Bone Chickens
Authors: Huang Yunyan , Li Shibao , Tan Yuting , Xu Chunhui , Huang Xuan , Yin Zhaozheng 
Published: February 2024

Introduction: Long non-coding RNA (lncRNA) refers to a category of non-coding RNA molecules exceeding 200 nucleotides in length, which exerts a regulatory role in the context of ovarian development. There is a paucity of research examining the involvement of lncRNA in the regulation of ovary development in Taihe Black-Bone Chickens. In order to further investigate the egg laying regulation mechanisms of Taihe Black-Bone Chickens at different periods, transcriptome analysis was conducted on the ovarian tissues at different laying periods.Methods: This study randomly selected ovarian tissues from 12 chickens for RNA-seq. Four chickens were selected for each period, including the early laying period (102 days, Pre), the peak laying period (203 days, Peak), and the late laying period (394 days, Late). Based on our previous study of mRNA expression profiles in the same ovarian tissue, we identified three differentially expressed lncRNAs (DE lncRNAs) at different periods and searched for their cis- and trans-target genes to draw an lncRNA-mRNA network.Results and discussion: In three groups of ovarian tissues, we identified 136 DE lncRNAs, with 8 showing specific expression during the early laying period, 10 showing specific expression during the peak laying period, and 4 showing specific expression during the late laying period. The lncRNA-mRNA network revealed 16 pairs of lncRNA-target genes associated with 7 DE lncRNAs, and these 14 target genes were involved in the regulation of reproductive traits. Furthermore, these reproductive-related target genes were primarily associated with signaling pathways related to follicle and ovary development in Taihe Black-Bone Chickens, including cytokine-cytokine receptor interaction, TGF-beta signaling pathway, tyrosine metabolism, ECM-receptor interaction, focal adhesion, neuroactive ligand-receptor interaction, and cell adhesion molecules (CAMs). This study offers valuable insights for a comprehensive understanding of the influence of lncRNAs on poultry reproductive traits.
Promoting informed decision making about maternal pertussis vaccination: the systematic development of an online tailored decision aid and a centering-based group antenatal care intervention
Authors: Anraad Charlotte , van Empelen Pepijn , Ruiter Robert A. C. , Rijnders Marlies , van Groessen Katja , van Keulen Hilde M. 
Published: February 2024

IntroductionMaintaining and enhancing vaccine confidence continues to be a challenge. Making an informed decision not only helps to avoid potential future regret but also reduces susceptibility to misinformation. There is an urgent need for interventions that facilitate informed decision-making about vaccines. This paper describes the systematic development of two interventions designed to promote informed decision making and indirectly, acceptance of maternal pertussis vaccination (MPV) in the Netherlands.Materials and methodsThe 6-step Intervention Mapping (IM) protocol was used for the development of an online tailored decision aid and Centering Pregnancy-based Group Antenatal Care (CP) intervention. A needs assessment was done using empirical literature and conducting a survey and focus groups (1), intervention objectives were formulated at the behavior and determinants levels (2), theoretical methods of behavior change were selected and translated into practical applications (3), which were further developed into the two interventions using user-centered design (4). Finally, plans were developed for implementation (5), and evaluation (6) of the interventions.ResultsThe needs assessment showed that pregnant women often based their decision about MPV on information sourced online and conversations with their partners, obstetric care providers, and peers. Responding to these findings, we systematically developed two interactive, theory-based interventions. We created an online tailored decision aid, subjecting it to four iterations of testing among pregnant women, including those with low literacy levels. Participants evaluated prototypes of the intervention positively on relevance and usability. In addition, a CP intervention was developed with midwives.ConclusionUsing IM resulted in the creation of an online decision aid and CP intervention to promote informed decision making regarding MPV. This description of the systematic development of the interventions not only serves to illustrate design rationales, it will also aid the interpretation of the evaluation of the interventions, the development of future interventions promoting informed decision and acceptance of vaccines, and comparisons with other interventions.
A retrospective study of variations in the kinds of diseases discharged from the Department of Infectious Diseases of a large general hospital in Central China during 2013–2019
Authors: Ye Pian , Zhao Lei , Pang Ran , Zheng Xin 
Published: February 2024

ObjectiveTo analyze the changing trend of the absolute number and constituent ratio of various in-patient diseases in the Department of Infectious Diseases of a large general hospital in Central China during 2013–2019.MethodsA retrospective study was conducted to analyze the diagnostic data of discharged patients for seven consecutive years, from 2013 to 2019. The first discharge diagnosis is used as the basis for the disease classification. The absolute number, constituent ratio, and changing trend of major diseases in hepatobiliary diseases and infectious diseases were analyzed.ResultsThe changing trend of the diseases during 2013–2019 showed that the absolute number of cases of hepatobiliary disease did not change significantly (p = 0.615), while the constituent ratio decreased significantly, from 68.01% in 2013 to 55.29% in 2019 (p&lt;0.001). The absolute number (constituent ratio) of cases of infectious diseases increased significantly from 585 (21.91%) in 2013 to 1,244 (36.86%) in 2019 (p = 0.015, p&lt;0.001). The major part of the increase was non-communicable infectious diseases (NCIDs).ConclusionDuring 2013–2019, the proportion of cases of hepatobiliary disease gradually decreased. The absolute number and proportion of cases of infectious diseases, especially NCIDs, have increased rapidly.
Mediating effects of social support and presenteeism on turnover intention and post-traumatic stress disorder among Chinese nurses in the post-pandemic era: a cross-sectional study
Authors: Zhang Jingshuo , Yang Xin , Zhang Xiaoman , Liu Yuping , Liu Mengshi , Fang Yu , Liu Mengjie , Wu Min 
Published: February 2024

BackgroundThe shift in national policies for epidemic prevention and control in the post-pandemic era is undoubtedly a challenge for health care professionals. Nurses, as an important part of the health care professional population, have an even greater impact on their mental health and occupational safety. This may expose nurses to post-traumatic stress disorder (PTSD) and presenteeism, and ultimately lead to their turnover.ObjectiveThis study aimed to investigate the relationship between turnover intention and post-traumatic stress disorder among Chinese nurses during post-pandemic era, and the mediating role of social support and presenteeism.MethodsIn this study, a multicentre cross-sectional survey was conducted in April 2023 among nursing staff in several tertiary general hospitals in northern China, with online data collection using the Turnover intention Scale (PTSD), the Impact of Events Scale (IES), the Social Support Scale (SSS), and the Stanford presenteeism Scale (STAS) and the relationship between variables was analyzed using hierarchical multivariate regression, and Structural Equation Modeling (SEM) was used to analyze the relationship between post-traumatic stress disorder and the Turnover intention from the pathway between.ResultsData were collected from 2,513 nurses who met the inclusion criteria, in which general information such as age, department, specific department, Professional title, history of alcohol consumption, form of employment, Years of working, and Average working hours per day were statistically significant with the difference in the turnover intention. The results of the study showed a 32% high turnover intention among nurses in the post-pandemic era, which was lower than the turnover intention during the pandemic. The results of hierarchical multiple regression analysis showed that post-traumatic stress disorder, social support, and presenteeism were significant predictors of turnover intention. The total effect of post-traumatic stress disorder on turnover intention to work was 0.472 [bias modified 95% confidence interval (0.415–0.483), p &lt; 0.001]. Social support and attendance played a partially intermediate role in post-traumatic stress disorder and propensity to leave (an indirect effect of 26% of the total effect).ConclusionTurnover intention and post-traumatic stress disorder levels are high and social support plays an important role in the tendency to leave the job and post-traumatic stress disorder, healthcare institution can be achieved by strengthening social support for nurses in the post-epidemic era and preventing the occurrence of presenteeism.
Transporting and implementing a caregiver-mediated intervention for toddlers with autism in Goa, India: evidence from the social ABCs
Authors: Brian Jessica A. , Dowds Erin M. , Bernardi Kate , Velho Andre , Kantawalla Mahera , de Souza Nandita 
Published: February 2024

IntroductionAutism is a global health priority with an urgent need for evidence-based, resource-efficient, scalable supports that are feasible for implementation in low- and middle-income countries (LMICs). Initiating supports in the toddler years has potential to significantly impact child and family outcomes. The current paper describes the feasibility and outcomes associated with a Canadian-developed caregiver-mediated intervention for toddlers (the Social ABCs), delivered through a clinical service in Goa, India.MethodsClinical staff at the Sethu Centre for Child Development and Family Guidance in Goa, India, were trained by the Canadian program development team and delivered the program to families seen through their clinic. Using a retrospective chart review, we gathered information about participating families and used a pre-post design to examine change over time.ResultsSixty-four families were enrolled (toddler mean age = 28.5 months; range: 19–35), of whom 55 (85.94%) completed the program. Video-coded data revealed that parents learned the strategies (implementation fidelity increased from M = 45.42% to 76.77%, p &lt; .001, with over 90% of caregivers attaining at least 70% fidelity). Toddler responsivity to their caregivers (M = 7.00% vs. 46.58%) and initiations per minute (M = 1.16 vs. 3.49) increased significantly, p's &lt; .001. Parents also reported significant improvements in child behaviour/skills (p &lt; .001), and a non-significant trend toward reduced parenting stress (p = .056).DiscussionFindings corroborate the emerging evidence supporting the use of caregiver-mediated models in LMICs, adding evidence that such supports can be provided in the very early years (i.e., under three years of age) when learning may be optimized.
Machine learning data sources in pediatric sleep research: assessing racial/ethnic differences in electronic health record–based clinical notes prior to model training
Authors: Davenport Mattina A. , Sirrianni Joseph W. , Chisolm Deena J. 
Published: February 2024

IntroductionPediatric sleep problems can be detected across racial/ethnic subpopulations in primary care settings. However, the electronic health record (EHR) data documentation that describes patients' sleep problems may be inherently biased due to both historical biases and informed presence. This study assessed racial/ethnic differences in natural language processing (NLP) training data (e.g., pediatric sleep-related keywords in primary care clinical notes) prior to model training.MethodsWe used a predefined keyword features set containing 178 Peds B-SATED keywords. We then queried all the clinical notes from patients seen in pediatric primary care between the ages of 5 and 18 from January 2018 to December 2021. A least absolute shrinkage and selection operator (LASSO) regression model was used to investigate whether there were racial/ethnic differences in the documentation of Peds B-SATED keywords. Then, mixed-effects logistic regression was used to determine whether the odds of the presence of global Peds B-SATED dimensions also differed across racial/ethnic subpopulations.ResultsUsing both LASSO and multilevel modeling approaches, the current study found that there were racial/ethnic differences in providers' documentation of Peds B-SATED keywords and global dimensions. In addition, the most frequently documented Peds B-SATED keyword rankings qualitatively differed across racial/ethnic subpopulations.ConclusionThis study revealed providers' differential patterns of documenting Peds B-SATED keywords and global dimensions that may account for the under-detection of pediatric sleep problems among racial/ethnic subpopulations. In research, these findings have important implications for the equitable clinical documentation of sleep problems in pediatric primary care settings and extend prior retrospective work in pediatric sleep specialty settings.
The Transformative Impact of Community-Led Monitoring in the South African Health System: A Comprehensive Analysis
Authors: Tshuma Ndumiso , Elakpa Daniel Ngbede , Moyo Clinton , Soboyisi Melikhaya , Moyo Sehlule , Mpofu Sihlobosenkosi , Chadyiwa Martha , Malahlela Mokgadi , Tiba Caroline , Mnkandla David , Ndhlovu Tshepo M. , Moruthoane Tsenolo , Mphuthi David D. , Mtapuri Oliver 
Published: February 2024

Objectives: Community-led monitoring (CLM) is an emerging approach that empowers local communities to actively participate in data collection and decision-making processes within the health system. The research aimed to explore stakeholder perceptions of CLM data and establish a CLM Data Value Chain, covering data collection and its impact.Methods: Qualitative data were collected from stakeholders engaged in health programs in South Africa. Data analysis involved a collaborative workshop that integrated elements of affinity diagramming, thematic analysis, and the systematic coding process outlined in Giorgi’s method. The workshop fostered joint identification, co-creation of knowledge, and collaborative analysis in developing the data value chain.Results: The findings showed that CLM data enabled community-level analysis, fostering program advocacy and local collaboration. It enhanced program redesign, operational efficiency, and rapid response capabilities. Context-specific solutions emerged through the CLM Data Value Chain, promoting sustainable and efficient program implementation.Conclusion: CLM is a powerful tool for improving program implementation, quality, and advocacy in South African healthcare. It strengthens accountability, trust, and transparency by involving local communities in data-driven decision-making. CLM addresses context-specific challenges and tailors interventions to local needs.
Green Marketing: Gains and Opportunities
Authors: Naveen Kumar C.M 
Published: February 2024

The promotion of eco-friendly initiatives, services, and products is referred to as green marketing. It involves a wide range of strategies and practices. Examples of this include the creation of eco-friendly products. Products marketed as environmentally safe are called “green marketing.” This practice involves a wide range of activities, such as product modification and the use of sustainable materials. It is essential for the existence of humans. It may take a long time to achieve this goal, but it will be very profitable. The key components of this strategy include the promotion of the product, the price, and the place of the product. These factors should be modified in order to encourage green marketing and reduce waste. The concept of green marketing has gained widespread recognition in the modern market. It has allowed companies to re-market and packages their products according to guidelines that are already in place. It has also opened up the possibility of companies branding their products in a way that promotes the green credentials of some while ignoring others. The concept of green marketing is gaining popularity in India. It is a strategy that aims to encourage environmentally friendly practices in the country. It is also used to promote products that are made from sustainable materials. Due to the increasing environmental hazards, it is very important that companies create awareness about the importance of protecting the environment. This paper aims to provide a comprehensive overview of the various aspects of green marketing in the Indian market. This paper also explores the various advantages of green marketing and its challenges. It explains the reasons why companies are starting to adopt this strategy.
Echoes of ‘Untouchable Lives’: A Study on Bama’s Sangati as a Dalit Feminist Narrative
Authors: Deepa Lakshmi P 
Published: February 2024

Literature is as old as human language. It has the power to transcend the boundaries across the world, thereby sharing all kinds of human experiences. Seen as a reflection of the society and the people residing in it, literature mirrors the lives of those who are marginalized as well as secluded from the mainstream society. And when it comes in the Indian context, it is the Dalit community becomes the utmost victims of the traumas of marginalization. As a part of the literature of the marginalized , Dalit literature enabled the articulation of the growing aspirations of Dalits in a new language. This paper is an attempt to analyse the rigid caste barriers existing in the Indian society and also examines how literature has emerged as an iconic tool in sharing the hopes and aspirations of Dalits, previously branded as ‘the untouchables. This paper also examines how Tamil Dalit Feminist writer Bama’s novel Sangati becomes an epitome of Dalit feminist narrative.
MODEL COOPERATIVE LEARNING TIPE JIGSAW BERBASIS BOOKLET MAKROINVERTEBRATA UNTUK MENINGKATKAN HASIL BELAJAR DI SMA NEGERI 7 KOTA BENGKULU
Authors: Salmeri Salmeri 
Published: February 2024

Penelitian bertujuan mendeskripsikan aktivitas guru, peserta didik, serta hasil belajar
psikomotorik dan kognitif peserta didik melalui penerapan model Cooperative Learning tipe
Jigsaw menggunakan booklet makroinvertebrata. Jenis penelitian ini adalah penelitian tindakan
kelas dengan model Kemmis dan Mc Taggart yang dilakukan sebanyak 2 siklus yang tiap
siklusnya terdiri dari perencanaan, tindakan, pengamatan, dan refleksi. Subjek penelitian adalah
guru dan peserta didik kelas X MIPA 2 SMA Negeri 7 Kota Bengkulu tahun ajaran 2022/2023.
Data dikumpulkan dengan cara observasi dan tes serta menggunakan instrumen penelitian
berupa lembar observasi dan lembar tes. Hasil analisis aktivitas guru siklus I diperoleh nilai 47,5
(baik) dan siklus II 52 (baik). Hasil analisis aktivitas peserta didik siklus I diperoleh nilai 46
(baik) dan siklus II 51,5 (baik). Analisis hasil belajar psikomotorik siklus I diperoleh nilai 10
(cukup) dan siklus II diperoleh nilai 13 (baik). Hasil belajar kognitif siklus I sebesar 72, 22 %
(belum tuntas) dan siklus II 83,33% (tuntas). Dari hasil penelitian disimpulkan bahwa
penerapan model Cooperative Learning tipe Jigsaw menggunakan booklet makroinvertebrata
mampu meningkatkan aktivitas dan hasil belajar peserta didik kelas X MIPA 2 SMA Negeri 7
Kota Bengkulu.
Kata Kunci: Cooperative Learning Tipe Jigsaw, Booklet, Makroinvertebrata, Hasil Belajar.
INVENTARISASI TUMBUHAN SEBAGAI OBAT TRADISIONAL DI KECAMATAN TAMBUN UTARA, KABUPATEN BEKASI
Authors: Karenina  , Devi anugrah  , Rahmi  
Published: February 2024

Indonesia mempunyai jenis flora dan fauna dengan persebaran yang sangat tinggi dan Indonesia merupakan negara yang mempunyai kekayaan tumbuhan Penelitian ini bertujuan untuk untuk mengetahui jenis-jenis tumbuhan obat tradisional di Kabupaten Bekasi Kecamatan Tambun Utara. Inventarisasi tumbuhan obat di Kabupaten Bekasi Kecamatan Tambun Utara sebelumnya belum pernah ada penelitian di daerah tersebut, karena itu meneruskan pengetahuan tentang tumbuhan obat di daerah dengan cara mendokumentasikan nama tumbuhan, manfaat dari tumbuhan. Penelitian ini dilakukan pada bulan Maret 2021. Penelitian ini dilaksanakan delapan desa di Kecamatan Tambun Utara Kabupaten Bekasi. Metode yang digunakan deskriptif kualitatif dengan cara pengumpulan data. Observasi yang dilakukan di lapangan dengan menggunakan metode jelajah (crulse method). Kabupaten Bekasi merupakan wilayah dengan perbatasan Jakarta, Karawang dan Bogor. Kabupaten Bekasi mempunyai luas 127.388 Ha yang terbagi menjadi 30 kecamatan, 245 desa dan 8 kelurahan. Dengan jumlah penduduk pada tahun 2017 sebanyak 12.378 orang, untuk luas dareh Tambun Utara sekitar 3.442 Ha. Hasil penelitian ditemukan pada Kecamatan Tambun Utara sebanyak 129 jenis tumbuhan obat dan 58 family. Desa yang paling banyak ditemukan adalah desa Jejalen Jaya. Family yang paling banyak digunakan yaitu family zingiberaceae. Organ yang paling banyak digunakan adalah daun. Teknik pengolahan yang paling banyak dengan cara direbus 44%, ditumbuk 12%, dihaluskan 12%, ditumbuk 10%, diseduh 8%, diparut 4%, dipotong 3%, dikeringkan 2%, diperas 1%, dijus 1%.

Kata kunci : Inventarisasi, tumbuhan obat, kabupaten bekasi
KEMAMPUAN PEMECAHAN MASALAH MODEL PEMBELAJARAN PJBL DAN PBL PADA PEMBELAJARAN IPA DI SMP NEGERI 02 SEBERANG MUSIv
Authors: Mahali Jalaluddin 
Published: February 2024

Penelitian ini untuk mengetahui perbedaan kemampuan pemecahan masalah pada pembelajaran IPA menggunakan model pembelajaran Project Based Learning (PjBL) dan Problem Based Learning (PBL) di SMP Negeri 02 Seberang Musi. Jenis penelitian quasi eksperimen. Populasi dalam penelitian ini adalah seluruh siswa kelas VIII sebanyak 2 kelas. Teknik pengambilan sampel dengan cara total sampel. Kelas dibagi menjadi 3 kelas secara purposive sampling. Desain penelitian menggunakan non-equivalent control group pretest-posttest design. Pengumpulan data menggunakan lembar tes kemampuan pemecahan masalah. Data dianalisis menggunakan uji one way anova. Hasil penelitian menunjukkan terdapat perbedaan Kemampuan Pemecahan Masalah menggunakan model pembelajaran Project Based Learning (PjBL) dan Problem Based Learning (PBL) serta pembelajaran Konvensional. Model Pembelajaran Problem Based Learning (PBL) lebih baik digunakan dalam Kemampuan Pemecahan Masalah dibandingkan model Project Based Learning (PjBL) dan konvensional pada pembelajaran IPA di SMP Negeri 02 Seberang Musi.

Kata kunci : Kemampuan Pemecahan Masalah, PjBL, PBL