bluuebunny/crossref_metadata_2025_split huggingface dataset:
Therapeutic alliance in two forms of guided self‐help for binge eating
Authors: Jenkins Paul E. , Wake Shannon 
Published: February 2024

AbstractThe role of therapeutic alliance within psychological treatments for eating disorders (EDs), including those delivered remotely, is well established. However, few studies have investigated alliance in guided self‐help, a widely recommended first‐line treatment for EDs characterised by regular binge eating. Using data from a randomised controlled trial, the current study examined both facilitator and patient assessments of alliance within e‐mail‐assisted and face‐to‐face guided self‐help and looked at associations between alliance, ED symptoms and ED‐related impairment. One hundred thirteen patients and 11 facilitators completed measures of alliance during and following a course of guided self‐help. Whilst ratings were reliable across patients and facilitators, alliance scores were higher both in the patient sample and in the face‐to‐face condition. Ratings of alliance showed no correlations with ED symptoms at post‐treatment, and early alliance was not significantly associated with outcome, which could inform how early symptom change is encouraged in guided self‐help.
Heteroatom Structural Engineering of Conjugated Porous Polymers Enhances Photocatalytic Nicotinamide Cofactor Regeneration
Authors: Wang Yujie , Yue Xiaoyang , Zhao Hao , Ma Li , Zhou Liya , Liu Yunting , Zheng Xiaobing , He Ying , Liu Guanhua , Jiang Yanjun 
Published: February 2024

AbstractPhotocatalysis is an eco‐friendly method to regenerate nicotinamide (NADH) cofactors, which is essential for biotransformation over oxidoreductases. Organic polymers exhibit high stability, biocompatibility and functional designability as photocatalysts, but still suffering from rapid charge recombination. Herewith the heteroatom structural engineering of donor‐π‐acceptor (D‐π‐A) conjugated porous polymers were conducted to promote charge transfer and photocatalytic NADH regeneration. The electron delocalization of polymer photocatalysts can be readily tuned by changing the electron density of the donor unit, leading to faster charge separation and better photocatalytic performance. The optimum sulfur‐doped polymer exhibits the highest NADH regeneration yield of 47.4 % in 30 min and 94.1 % in 4 h, which can drive the biocatalytic C=C bond reduction of 2‐cyclohexen‐1‐one by ene‐reductase, giving the corresponding cyclohexanone yield of 96.7 % in 10 h. Moreover, the oxygen‐doped polymer, from biomass derived 2,5‐diformylfuran, exhibits comparable photocatalytic activity to the sulfur‐doped CPP, suggesting the potential of furan as alternative donor unit to thiophene.
The involvement of RNA N6‐methyladenosine and histone methylation modification in decidualization and endometriosis‐associated infertility
Authors: Lin Xiang , Dai Yongdong , Gu Weijia , Zhang Yi , Zhuo Feng , Zhao Fanxuan , Jin Xiaoying , Li Chao , Huang Dong , Tong Xiaomei , Zhang Songying 
Published: February 2024

AbstractDefective decidualization of endometrial stromal cells (ESCs) in endometriosis (EM) patients leads to inadequate endometrial receptivity and EM‐associated infertility. Hypoxia is an inevitable pathological process of EM and participates in deficient decidualization of the eutopic secretory endometrium. Enhancer of zeste homology 2 (EZH2) is a methyltransferase which catalyses H3K27Me3, leading to decreased expression levels of target genes. Although EZH2 expression is low under normal decidualization, it is abundantly increased in the eutopic secretory endometrium of EM and is induced by hypoxia. Chromatin immunoprecipitation‐PCR results revealed that decidua marker IGFBP1 is a direct target of EZH2, partially explaining the increased levels of histone methylation modification in defected decidualization of EM. To mechanism controlling this, we examined the effects of hypoxia on EZH2 and decidualization. EZH2 mRNA showed decreased m6A modification and increased expression levels under hypoxia and decidualization combined treatment. Increased EZH2 expression was due to the increased expression of m6A demethylase ALKBH5 and decreased expression of the m6A reader protein YTHDF2. YTHDF2 directly bind to the m6A modification site of EZH2 to promote EZH2 mRNA degradation in ESCs. Moreover, selective Ezh2 depletion in mouse ESCs increased endometrial receptivity and improved mouse fertility by up‐regulating decidua marker IGFBP1 expression. This is the first report showing that YTHDF2 can act as a m6A reader to promote decidualization by decreasing the stability of EZH2 mRNA and further increasing the expression of IGFBP1 in ESCs. Taken together, our findings highlight the critical role of EZH2/H3K27Me3 in decidualization and reveal a novel epigenetic mechanism by which hypoxia can suppress EM decidualization by decreasing the m6A modification of EZH2 mRNA.
Development of Monte Carlo neutral transport code and the application to methane seeding plasma detachment
Authors: Bian Yu , Wang Yilin , Sang Chaofeng , Wu Yihan , Zhang Mingzhou , Wang Yue 
Published: February 2024

AbstractThe collisions between neutral particles and plasma in the divertor region determine divertor detachment and heat flux to the target. However, the diagnostic of neutral particle information in the tokamak experiment is very lacking. To study the behavior of neutral particles in the boundary region flexibly and comprehensively, a two‐dimensional kinetic neutral transport code based on Monte Carlo method is developed in this work. The code is applied to simulate the neutral particles in the boundary of EAST device. Firstly, the simulation results are compared with EIRENE using an identical plasma background, and good agreement is obtained. Secondly, the transport of methane and the corresponding hydrocarbon compounds is simulated using the developed code. The methane injection case is compared with the injection of carbon and deuterium molecule mixture gas (ratio 1:2) to investigate their impact on detachment and fueling. The simulation reveals that, compared to the direct carbon atom injection case, charge‐exchange collision is the dominant collision of neutral methane (hydrocarbons), which suppresses divertor power radiation and plasma detachment while promoting the improvement of fueling efficiency.
Experimental verification of voltage boost control in a hybrid system using D‐EPC
Authors: Matsuno Hiroki , Akiyama Hiromu , Yoshimoto Kantaro , Yokoyama Tomoki 
Published: February 2024

AbstractA novel voltage boost system using DC‐inputs direct electric‐power converter (D‐EPC) is proposed. D‐EPC is an inverter that can control the distribution of power from two sources. In this study, a voltage boost system without boost chopper was developed using the power distribution control of D‐EPC. The power distribution control can control the voltage of the smoothing capacitor in the D‐EPC. The effectiveness of the proposed voltage boost system was verified using a prototype of the D‐EPC circuit and controller.
Effect of Ge Incorporation on Lead‐free Cs‐based Triiodide Sn−Ge Co‐alloy Perovskite Thin Films by Spin Coating
Authors: Li Hongyu , Ye Chao , Yang Jianming , Jiang Yu , Wu Zhifang , Donaev Sardor Burkhanovich , Wang Shenghao 
Published: February 2024

AbstractA new Sn−Ge co‐alloy perovskite that does not contain toxic Pb is attracting attention due to its excellent predicted optoelectronic properties. However, most current research only focuses on compositions with Ge content up to 50 %, resulting in a limited overall understanding on this material system. In this study, CsSn1–xGexI3 (0≤x≤1) perovskite thin films were fabricated using spin coating method and characterized in terms of crystallographic, morphological and optical characteristics systematically. The results show that the Ge incorporation causes lattice shrinkage and a change in the crystallographic phase from orthorhombic to trigonal. Additionally, the coverage varies much as Ge increases. The Ge incorporation also results in a blueshift of the photoluminescence peak and a decrease in luminescence intensity as compared to the composition with lower Ge content. Moreover, the carrier dynamics measurement shows that the Ge incorporation increases the carrier nonradiative recombination. This work provides important hints for the development of the Sn−Ge alloy‐based perovskite solar cell.
Rational Design of Metallylenes for Hydrogenation Reactions
Authors: Tiekink Eveline H. , Lekanne Deprez Siebe , Vermeeren Pascal , Hamlin Trevor A. 
Published: February 2024

AbstractThe hydrogenation of alkenes, alkynes, carbonyls, and imines by H2‐activated metallylenes (H3C−EH2−L, CELH2; E=Si, Ge, Sn and L=NMe2, PMe2) was studied using relativistic density functional theory at ZORA‐BP86/TZ2P. By means of activation strain and Kohn–Sham molecular orbital analyses, the physical factors underlying the trends in reactivity were identified and quantified. Firstly, the hydrogenation reactivity increases on descending Group 14, that is from silylenes (E=Si) to stannylenes (E=Sn). This reactivity trend originates primarily from a reduced energy required to break the bonds between the Group 14 atom and the hydrogen atoms because the strength of these bonds decreases from Si−H to Ge−H to Sn−H. Secondly, the reactivity decreases as the Group 15 ligand changes from nitrogen to phosphorus (L=NMe2, PMe2) which stems from the trigonal pyramidal PMe2 geometry compared to the trigonal planar NMe2 geometry. The latter can, therefore, effectively engage in stronger orbital interactions with the substrate than the former, due to a more efficient HOMO–LUMO orbital overlap. By combining our insights, we rationally designed an optimally tuned catalyst (Group 14 atom and ligand) considering the overall catalytic cycle involving H2 activation of the metallylene and subsequent hydrogenation.
Particle focusing mechanisms in λ‐DNA solution flowing in a straight microchannel
Authors: Chen Dalin , Huang Qiang , Ni Zhonghua , Xiang Nan 
Published: February 2024

AbstractMost biological fluids (such as blood, saliva, and lymph) in nature have certain viscoelasticity and are beginning to be used as the carrying fluids for viscoelastic microfluidics. However, the particle‐focusing mechanisms in these new biological viscoelastic fluids are still unclear. In this work, the particle‐focusing mechanisms in λ‐DNA solutions were systematically explored. We first explored the particle focusing dynamics in a square cross‐section under varied flow rates to uncover the effects of flow rate on particle focusing. Three focusing stages, from the classic five‐position viscoelastic focusing to single‐stream focusing and finally to multiplex‐stream focusing, were clearly demonstrated. In addition, the particle focusing process along the channel length was demonstrated, and a first‐fast‐and‐then‐slow focusing process was clearly observed. Then, the effects of λ‐DNA concentrations on particle focusing were explored and compared using the solutions with 0–25 ppm λ‐DNA. Finally, we discussed the inferences of blockage ratio on particle focusing by changing the particle diameter and cross‐sectional dimensions. Our work may provide a deeper understanding on the particle focusing mechanisms in biological viscoelastic fluids and lays a foundation for the subsequent particle counting and analysis and the development of low‐cost portable flow cytometers.
Scaffolding future Latinx evaluators toward racial justice: Lessons learned from Stafford
Authors: Sperling Rick , Quetzeri Vanessa , Cuevas Azucena , Martinez Melanie 
Published: February 2024

AbstractContinuing the journey of culturally responsive evaluation (CRE) requires attending to the ways in which we prepare future evaluators. That means moving beyond treating evaluator education as a one size fits all technical exercise. We must take into consideration student identities and experiences, as well as historical and contemporary ideological currents, many of which are at odds with CRE principles and work against our own values. In this article, we, the program director, two graduates, and one current student in St. Mary's University's academic certificate program in Community‐based Assessment and Evaluation, share our experiences with evaluator education at a Hispanic‐Serving Institution. Collectively, we have come to realize that the pursuit of cultural competence often requires resisting both feigned color‐blindness and outright racism as they exist outside and inside of ourselves. Our success depends on applying core ideas of CRE to the evaluator education process by recognizing and responding to ourselves as actors within a sociopolitical and cultural context. Only by giving ourselves and our positionality the same attention we give community members can we do justice to the evaluator education process. Hopefully, our stories will enliven discussion on how best to amplify the power of our emerging evaluators as they begin their careers.
Tracing the relationship(s) of CRE and LGBTQ+ Evaluation
Authors: Felt Dylan , Phillips Gregory , Miller Robin L. 
Published: February 2024

AbstractThis article explores the close relationships between LGBTQ+ Evaluation (LGBTQ+E) and Culturally Responsive Evaluation (CRE). First, we consider the role of CRE spaces, scholars, and practitioners in supporting LGBTQ+E, including Dr. Stafford Hood, who helped us break through barriers that kept LGBTQ+E practices marginalized in the evaluation canon. We reflect on parallel developmental trajectories, and explore how LGBTQ+E embodies CRE. Finally, we discuss how LGBTQ+E and CRE can evolve through deepening their relationships and attending more meaningfully to intersectional and international work.
Calling it like we see it!: Our reflections, positionality, and vision for CRE's future
Authors: Thomas Veronica G. , Bledsoe Katrina L. 
Published: February 2024

AbstractThis article highlights the reflections and positionality of two African American women evaluators who have unapologetically integrated their professional and personal identities into their culturally responsive evaluation (CRE) scholarship and practice. After a brief overview of culturally responsive evaluation (CRE), the authors describe how their positionality and intersectionality as African American women (among other identities) inevitably frame their evaluative thinking and practice. Subsequently, they describe critical moments in their CRE journey over the past 25 years, particularly illuminating the influence of Stafford Hood. They conclude with a vision for CRE as a tool to help reduce inequalities and improve the lives of individuals and communities, especially those often marginalized and excluded.
Epilogue: The view from here
Authors: Hall Melvin E. 
Published: February 2024

AbstractThis NDE volume has recounted the legacy of Stafford Hood from multiples angles of vision. This Epilogue centers the original 1998 conceptualization of culturally responsive evaluation and discusses how a diverse professional community came together to dialogue, debate, reflect, and create, fleshing out culturally responsive evaluation and assessment in both theory and practice. Three conference themes—from CREA I, CREA V, and CREA VII—illustrate these critical conversations. The Epilogue closes with Stafford's exhortations on our responsibilities as culturally responsive evaluators and assessment specialists.
A novel stabilized nodal integration formulation using particle finite element method for incompressible flow analysis
Authors: Yu Lu‐Jia , Jin Yin‐Fu , Yin Zhen‐Yu , Chen Jian‐Fei 
Published: February 2024

AbstractIn simulations using the particle finite element method (PFEM) with node‐based strain smoothing technique (NS‐PFEM) to simulate the incompressible flow, spatial and temporal instabilities have been identified as crucial problems. Accordingly, this study presents a stabilized NS‐PFEM‐FIC formulation to simulate an incompressible fluid with free‐surface flow. In the proposed approach, (1) stabilization is achieved by implementing the gradient strain field in place of the constant strain field over the smoothing domains, handling spatial and temporal instabilities in direct nodal integration; (2) the finite increment calculus (FIC) stabilization terms are added using nodal integration, and a three‐step fractional step method is adopted to update pressures and velocities; and (3) a novel slip boundary with the predictor–corrector algorithm is developed to deal with the interaction between the free‐surface flow with rigid walls, avoiding the pressure concentration induced by standard no‐slip condition. The proposed stabilized NS‐PFEM‐FIC is validated via several classical numerical cases (hydrostatic test, water jet impinging, water dam break, and water dam break on a rigid obstacle). Comparisons of all simulations to the experimental results and other numerical solutions reveal good agreement, demonstrating the strong ability of the proposed stabilized NS‐PFEM‐FIC to solve incompressible free‐surface flow with high accuracy and promising application prospects.
Age‐related subtypes of late life depression and mortality: A prospective clinical cohort study
Authors: Lugtenburg Astrid , Zuidersma Marij , Rius Ottenheim Nathaly , Rhebergen Didi , Oude Voshaar Richard C. 
Published: February 2024

AbstractObjectivesLate Life Depression (LLD) is associated with increased mortality rates, but it remains unclear which depressed patients are at increased risk. This study examined the mortality risk of previously identified subgroups of depressed older patients based on age‐related clinical features (the presence of physical and cognitive frailty).MethodsA six‐year follow‐up of a clinical cohort study including 375 depressed older patients and 132 non‐depressed persons (NESDO). Depressed patients were diagnosed with the Composite International Diagnostic Interview (CIDI) according to DSM‐IV criteria and classified by latent profile analysis on depressive symptom severity, cognitive domains and physical frailty. We estimated the hazard rate of mortality for the four depressed subgroups compared to non‐depressed persons by applying Cox‐regression analyses. Models were adjusted for age, sex and education as confounders and for explanatory variables per pathway in separate models: somatic burden, lifestyle characteristics, vascular burden or inflammation markers.ResultsA total of 61/375 (16.3%) depressed patients and 8/132 (6.1%) non‐depressed persons died during the 6‐year follow‐up. Two of the four subgroups (n = 186/375 (50%) of the depressed sample) had a higher hazard rate (HR) for mortality compared to non‐depressed participants, that is, frail‐depressed patients (HR = 5.25, [95%‐CI: 2.13–13.0]) and pure mild depressed patients (HR = 3.32 [95%‐CI: 1.46–7.58]) adjusted for confounders. Adding possible underlying pathways did not explain these associations.ConclusionsAge‐related features (the presence of physical and cognitive frailty) contribute to the increased mortality risk in late‐life depression. Future studies in depressed older patients should study the additional value of a clinical geriatric assessment and integrated treatment aimed to at reduce frailty and ameliorate their mortality risk.
A supervised machine learning model for identifying predictive factors for recommending head and neck cancer surgery
Authors: Jiam Max L. , Xin Kevin Z. , Ha Patrick K. , Jiam Nicole T. 
Published: February 2024

AbstractBackgroundNew patient referrals are often processed by practice coordinators with little‐to‐no medical background. Treatment delays due to incorrect referral processing, however, have detrimental consequences. Identifying variables that are associated with a higher likelihood of surgical oncological resection may improve patient referral processing and expedite the time to treatment. The study objective is to develop a supervised machine learning (ML) platform that identifies relevant variables associated with head and neck surgical resection.MethodsA retrospective cohort study was conducted on 64 222 patient datapoints from the SEER database.ResultsThe random forest ML model correctly classified patients who were offered head and neck surgery with an 81% accuracy rate. The sensitivity and specificity rates were 86% and 71%. The positive and negative predictive values were 85% and 73%.ConclusionsML modeling accurately predicts head and neck cancer surgery recommendations based on patient and cancer information from a large population‐based dataset. ML adjuncts for referral processing may decrease the time to treatment for patients with cancer.
Development of a Novel Measurement Setup to Study and Predict Electrostatic Discharges in Agitated Glass‐Lined Vessels
Authors: Brönnimann Benedikt Robert , Egli‐Tedesco Daniel , Schwenzfeuer Klaus , Zogg Andreas 
Published: February 2024

AbstractTwo glass lined reactors in a launch platform facility operated by Syngenta have been damaged during the crystallization of an organic compound due to electrostatic discharges. The goal of this work was to design and commission a novel setup to measure charges and currents generated by this slurry in a laboratory‐scale reactor. An improved and more sophisticated setup was then proposed for possible implementation in Syngenta's own laboratories. With this novel setup, the electrostatic charging of stirred suspensions involving nonconductive solvents could be accurately measured in the context of a case study that involved the suspension that led to liner damages in the production facilities of Syngenta.
A novel tool for risk assessment, screening, diagnosis, assessment, and therapy in postpartum depression
Authors: Sharma Prachi , Khera Kanav 
Published: February 2024

AbstractPostpartum depression (PPD), as a common condition occurring in women in the postnatal period, is underdiagnosed, seldom identified, and infrequently treated. Undiagnosed PPD can have negative consequences for overall quality‐of‐life outcomes in the mother, psychological growth of the infant, and bonding between the infant and its mother. However, early diagnosis and prompt treatment of PPD can lead to an improvement in postpartum maternal health and a healthier relationship between the mother and her infant. Additionally, early identification of risk factors in the prenatal and antenatal period can enable preventive treatment and ensure that the expectant or pregnant woman remains free of disease after giving birth. Therefore, we propose a protocol for the risk assessment, screening, diagnosis, assessment, and therapy of postnatal depression (RASDAT). The RASDAT protocol recommends assessment of risk factors for PPD in the perinatal period as well as early diagnosis and treatment in the early‐to‐mid postpartum period. It also recognizes, for the first time, insomnia and anxiety as important predictors, comorbidities, and poor prognostic factors in postpartum depression. Further studies are necessary to determine the feasibility and applicability of this novel tool, including costs of availing health facilities, burden on the health system, and knowledge, attitudes, and practices among physicians and clinical pharmacists regarding PPD and its resolution.