bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictions enable top-down pattern separation in the macaque face-processing hierarchy
Authors: Nigam Tarana , Schwiedrzik Caspar M. 
Published: October 2023

AbstractDistinguishing faces requires well distinguishable neural activity patterns. Contextual information may separate neural representations, leading to enhanced identity recognition. Here, we use functional magnetic resonance imaging to investigate how predictions derived from contextual information affect the separability of neural activity patterns in the macaque face-processing system, a 3-level processing hierarchy in ventral visual cortex. We find that in the presence of predictions, early stages of this hierarchy exhibit well separable and high-dimensional neural geometries resembling those at the top of the hierarchy. This is accompanied by a systematic shift of tuning properties from higher to lower areas, endowing lower areas with higher-order, invariant representations instead of their feedforward tuning properties. Thus, top-down signals dynamically transform neural representations of faces into separable and high-dimensional neural geometries. Our results provide evidence how predictive context transforms flexible representational spaces to optimally use the computational resources provided by cortical processing hierarchies for better and faster distinction of facial identities.
Microbiome imaging goes à la carte: Incorporating click chemistry into the fluorescence-activating and absorption-shifting tag (FAST) imaging platform
Authors: Anderson David M. , Logan Matthew G. , Patty Sara S. , Kendall Alexander J. , Borland Christina Z. , Pfeifer Carmem S. , Kreth Jens , Merritt Justin L. 
Published: October 2023

AbstractThe human microbiome is predominantly composed of facultative and obligate anaerobic bacteria that live in hypoxic/anoxic polymicrobial biofilm communities. Given the oxidative sensitivity of large fractions of the human microbiota, green fluorescent protein (GFP) and related genetically-encoded fluorophores only offer limited utility for live cell imaging due the oxygen requirement for chromophore maturation. Consequently, new fluorescent imaging modalities are needed to study polymicrobial interactions and microbiome-host interactions within anaerobic environments. The fluorescence-activating and absorption shifting tag (FAST) is a rapidly developing genetically-encoded fluorescent imaging technology that exhibits tremendous potential to address this need. In the FAST system, fluorescence only occurs when the FAST protein is complexed with one of a suite of cognate small molecule fluorogens. To expand the utility of FAST imaging, we sought to develop a modular platform (Click-FAST) to democratize fluorogen engineering for personalized use cases. Using Click-FAST, investigators can quickly and affordably sample a vast chemical space of compounds, potentially imparting a broad range of desired functionalities to the parental fluorogen. In this work, we demonstrate the utility of the Click-FAST platform using a novel fluorogen,PLBlaze-alkyne, which incorporates the widely available small molecule ethylvanillin as the hydroxybenzylidine head group. Different azido reagents were clicked ontoPLBlaze-alkyne and shown to impart useful characteristics to the fluorogen, such as selective bacterial labeling in mixed populations as well as fluorescent signal enhancement. Conjugation of an 80 Å PEG molecule toPLBlaze-alkyne illustrates the broad size range of functional fluorogen chimeras that can be employed. This PEGylated fluorogen also functions as an exquisitely selective membrane permeability marker capable of outperforming propidium iodide as a fluorescent marker of cell viability.
Spinocerebellar ataxia type 4 is caused by a GGC expansion in theZFHX3gene and is associated with prominent dysautonomia and motor neuron signs
Authors: Paucar Martin , Nilsson Daniel , Engvall Martin , Laffita-Mesa José , Söderhäll Cilla , Skorpil Mikael , Halldin Christer , Fazio Patrik , Lagerstedt-Robinson Kristina , Solders Göran , Angeria Maria , Varrone Andrea , Risling Mårten , Jiao Hong , Nennesmo Inger , Wedell Anna , Svenningsson Per 
Published: October 2023

AbstractBackgroundSpinocerebellar ataxias (SCAs) are a group of heterogeneous autosomal dominant disorders. Spinocerebellar ataxia 4 (SCA4), one of the rarest SCAs, is characterized by adult-onset ataxia, polyneuropathy and linked to chromosome 16q22.1, the underlying mutation remains to be discovered.MethodsThree Swedish families affected by undiagnosed SCA went through detailed examinations, neurophysiological tests, neuroimaging studies and genetic testing. Imaging included MRI of the neuroaxis and brain PET. In 3 cases neuropathological assessments were performed. Genetic testing included SR WGS, STR analysis with Expansion Hunterde novoand long read (LR) WGS.ResultsNovel features such as dysautonomia, motor neuron affection, and abnormal eye movements, were found. Anticipation was documented as well. Atrophy in the cerebellum, brainstem and spinal cord was found in patients studied with MRI. [18F]FDG-PET demonstrated brain hypometabolism whereas [11C]Flumazenil-PET yielded reduced binding in several brain lobes, insula, thalamus, hypothalamus and cerebellum. Neuropathological assessment revealed moderate to severe loss of Purkinje cells in the cerebellum. In the spinal cord a marked loss of motor neurons in the anterior horns was seen as well as pronounced degeneration of posterior tracts. Intranuclear, mainly neuronal, inclusions positive for p62 and ubiquitin were sparse but widespread in the CNS. This finding prompted assessment for nucleotide expansions. A poly-glycine stretch encoding GGC expansions in the last exon of the zink finger homeobox 3 (ZFHX3)gene was identified segregating with disease, and not found in 1000 controls.ConclusionsSCA4 is a neurodegenerative disease, caused by a novel GGC expansion inZFHX3,arguably the first polyglycine disorder in humans.
Photo-thermo-piezo-elastic waves in semiconductor medium subject to distinct two temperature models with higher order memory dependencies
Authors: Gupta Vipin , Barak M.S. 
Published: October 2023

Purpose
This study aims to examine the impacts of higher memory dependencies on a novel semiconductor material that exhibits generalized photo-piezo-thermo-elastic properties. Specifically, the research focuses on analyzing the behavior of the semiconductor under three distinct temperature models.

Design/methodology/approach
The study assumes a homogeneous and orthotropic piezo-semiconductor medium during photo-thermal excitation. The field equations have been devised to encompass higher order parameters, temporal delays and a specifically tailored kernel function to address the problem. The eigenmode technique is used to solve these equations and derive analytical expressions.

Findings
The research presents graphical representations of the physical field distribution across different temperatures, higher order plasma heat conduction models and time. The results reveal that the amplitude of the distribution profile is markedly affected by factors such as the memory effect, time, conductive temperature and spatial coordinates. These factors cannot be overlooked in the analysis and design of the semiconductor.

Research limitations/implications
Specific cases are also discussed in detail, offering the potential to advance the creation of precise models and facilitate future simulations.

Practical implications
The research offers valuable information on the physical field distribution across various temperatures, allowing engineers and designers to optimize the design of semiconductor devices. Understanding the impact of memory effect, time, conductive temperature and spatial coordinates enables device performance and efficiency improvement.

Originality/value
This manuscript is the result of the joint efforts of the authors, who independently initiated and contributed equally to this study.
The double reduction policy and education development in China
Authors: Zhong Keqing , Park Jae 
Published: October 2023

PurposeThis policy review paper is an analysis of the Double Reduction Policy (DRP) of China that was promulgated in July 2021. It looks into its rationale as well as different stakeholders' early reactions to the policy.Design/methodology/approachCritical policy analysis (CPA) method was used to identify (1) the artefacts, such as language, objects and acts, that were significant carriers of the DRP; (2) communities of meaning, interpretation, speech and practice that are relevant to the DRP and its implementation; (3) the local discourses relevant to the DRP; and (4) the tension points and their conceptual sources (affective, cognitive and/or moral) by different DRP stakeholders. As per the comparative education field, this paper compares the pre-DRP and post-DRP periods to tease out how the policy affects different stakeholders of education.FindingsThe DRP in China could be attributed to diverse factors such as demography, socialist economic and developmental visions and manpower structure. The implementation of the DRP has generated uneven reactions among different stakeholders and geographical regions both in speed and scale. While education stakeholders have no choice but to adopt the policy, they face challenges derived from a sudden halt of private educational resources and subsequent increased duties of parents and schools.Originality/valueThe significance of this early policy analysis lies in offering an insight into education development in China by analysing and deliberating the DRP from different perspectives.
Housing supply and development contributions: a case study of sidewalks in Seattle
Authors: Garza Nestor , Goldman Michael 
Published: October 2023

Purpose
This study aims to test the effect of Seattle’s discontinuous sidewalk requirement, on the number of housing units per construction permit.

Design/methodology/approach
This study uses discontinuity linear regression (DLR) on a database of Seattle’s housing construction permits during January-2015 to January-2018, controlled by 51 socioeconomic, planning and geographic variables. The sidewalk requirement is continuous inside the designated urban villages; however, it is spatially and quantitatively discontinuous in the rest of the city: certain blocks at certain locations require sidewalks’ design and construction in permits with six or more housing units. DLR detects the effect of the discontinuity while controlling for a vast array of confounding variables.

Findings
The primary finding is that the discontinuous requirement reduces the number of housing units in about 75% of a housing unit per permit, which at the aggregate level amounts to around 335 fewer housing units during the period of analysis.

Research limitations/implications
The database is relatively small, which has limited a more thorough specification process and robustness tests.

Originality/value
Besides directly testing the effect of a discontinuous in-kind development contribution, the research setup allows to discuss a wider, more structural problem: the possibility of contributions avoidance due to spatial substitution. In contrast, spatially continuous (i.e. city-level) contributions cannot be avoided by performing spatial substitution, and they are internalized by the housing supply side (market-neutral).
An empirical research on the determinants of driver-partners' participative behaviour in crowd logistics: from a motivation theory perspective
Authors: Nguyen Cam Tu , Yuen Kum Fai , Kim Thai Young , Wang Xueqin 
Published: October 2023

PurposeCrowd logistics is a rising phenomenon in last-mile delivery that integrates technological applications and sources a large number of participants to do logistical activities, achieving sustainable shipping in urban environments. However, up until now, there has been limited literature in this field. This research aims to investigate the extrinsic and intrinsic factors that impact the participative behaviour of driver-partners in crowd logistics.Design/methodology/approachAn integrated model is developed based on motivation theory, incorporating attitude as a contributor to both extrinsic and intrinsic motivations. A questionnaire was constructed and distributed to collect data from 303 respondents who are existing or potential driver-partners in Vietnam.FindingsOur findings confirm (1) the influence of monetary rewards on extrinsic motivation and (2) the power of self-efficacy, trust and sense of belonging on intrinsic motivation. Further, we find that attitude positively impacts extrinsic motivation, whereas there is no effect between attitude and intrinsic motivation. Both extrinsic and intrinsic motivations are demonstrated to significantly influence driver-partners' participative intentions. Additionally, a positive association is found between extrinsic and intrinsic motivations.Originality/valueFindings from this study theoretically enrich the literature on crowd logistics, especially on the supply side, and empirically contribute to implications that are valuable to crowd logistics firms on driver-partner recruitment and business strategy development.
User involvement and value co-creation in well-being ecosystems
Authors: Poblete León , Eriksson Erik , Hellström Andreas , Glennon Russ 
Published: October 2023

PurposeThis article aims to examine how users' involvement in value co-creation influences the development and orchestration of well-being ecosystems to help tackle complex societal challenges. This research contributes to the public management literature and answers recent calls to investigate novel public service governances by discussing users' involvement and value co-creation for novel well-being solutions.Design/methodology/approachThe authors empirically explore this phenomenon through a case study of a complex ecosystem addressing increased well-being, focussing on the formative evaluation stage of a longitudinal evaluation of Sweden's first support centre for people affected by cancer. Following an abductive reasoning and action research approach, the authors critically discuss the potential of user involvement for the development of well-being ecosystems and outline preconditions for the success of such approaches.FindingsThe empirical results indicate that resource reconfiguration of multi-actor collaborations provides a platform for value co-creation, innovative health services and availability of resources. Common themes include the need for multi-actor collaborations to reconfigure heterogeneous resources; actors' adaptive change capabilities; the role of governance mechanisms to align the diverse well-being ecosystem components, and the engagement of essential actors.Research limitations/implicationsAlthough using a longitudinal case study approach has revealed stimulating insights, additional data collection, multiple cases and quantitative studies are prompted. Also, the authors focus on one country but the characteristics of users' involvement for value co-creation in innovative well-being ecosystems might vary between countries.Practical implicationsThe findings of this study demonstrate the value of cancer-affected individuals, with “lived experiences”, acting as sources for social innovation, and drivers of well-being ecosystem development. The findings also suggest that participating actors in the ecosystem should utilise wider knowledge and experience to tackle complex societal challenges associated with well-being.Social implicationsPolicymakers should encourage the formation of well-being ecosystems with diverse actors and resources that can help patients navigate health challenges. The findings especially show the potential of starting from the user's needs and life situation when the ambition is to integrate and innovate in fragmented systems.Originality/valueThe proposed model proposes that having a user-led focus on innovating new solutions can play an important role in the development of well-being ecosystems.
Quality assurance strategies of higher education in digital era: an Anthropology of education study in Islamic higher education institution
Authors: Haddade Hasyim , Nur Askar , Rasyid Muhammad Nur Akbar , R. Abd Raviq 
Published: October 2023

Purpose
The purpose of this study is to demonstrate the strategy and innovation of the Faculty of Adab and Humanities in developing the quality of education in digital era by using anthropology of education approach.

Design/methodology/approach
In accordance with the research purpose to demonstrate the strategy and innovation of the Faculty of Adab and Humanities in developing the quality of education in the digital era using an educational anthropology approach, the method used is descriptive qualitative, which refers to data in the form of interviews obtained from the field.

Findings
The results of this research indicate that there are strategies and innovations to develop the quality of higher education at the Faculty of Adab and Humanities in the digital era. These include adjusting the curriculum with the context of the era, implementing the learning process based on research and reinforcing on aspects of digital literacy among students through the innovation of the library based on digital.

Originality/value
This study can be considered in the process of evaluating policies related to quality reinforcing strategies and innovations at the Faculty of Adab and Humanities in facing the challenges of the times. The study is only limited to tracing and analyzing strategies and innovations to reinforce education in the Faculty of Adab and Humanities and their impact on human resource development. For further research, it can be done in more detail and depth and on a larger scale.
Iranian EFL teachers’ knowledge and skills in a language teaching methodology course: a gap-analysis study
Authors: Javadi Mohammad , Sarkhosh Mehdi 
Published: October 2023

Purpose
This study aims to investigate the perceptions of Iranian English teachers about their teaching efficiency through a specific practicum course, namely, language teaching methodology. Drawing on a marketing education perspective, the researchers sought to measure the service quality offered in universities by examining teachers’ satisfaction with the curriculum.

Design/methodology/approach
Using quantitative gap analysis, the study evaluated the knowledge and skills of teachers in their preservice education regarding the perceived importance of knowledge and skills required in practice. The study involved 120 English as a foreign language teachers holding a BA degree from two universities in Iran, each with two to four years of teaching experience in the private sector. Data were collected using a 40-item semantic differential Likert scale developed by the researchers. The scale incorporated two components that assessed teachers’ perceived importance of knowledge and skills and their preservice educational preparation.

Findings
The findings revealed that most participants were overprepared in various items. However, there were some gaps in content knowledge and skills. Reasons for these gaps mainly included having adequate experience of and/or familiarity with course content, having completed relevant courses beforehand and imitating role model teachers. Teachers’ underpreparation was attributed to their lack of preparation in some specific subjects due to limited skill, practice, motivation, experience and familiarity with that content area.

Originality/value
This study explores the perceived knowledge and skills of Iranian English teachers and provides empirical insights into higher education service quality and customer satisfaction.
Perceptions of the textile industry stakeholders on a multi-slab goods and services tax system in India
Authors: Pandey Ashutosh , Saxena Nitin , Paliwal Udai 
Published: October 2023

Purpose
The purpose of this paper is to present the perception of the textile industry stakeholders (manufacturers, wholesalers, retailers, consumers and tax professionals) on India’s new goods and services tax (GST) system and find whether the introduction of GST has made doing business easier or not.

Design/methodology/approach
The researchers used interviews and surveys to capture the perceptions of the textile industry stakeholders at Surat, a major textile hub in India. To econometrically verify the perceptions, the researchers used a logit regression model.

Findings
The researchers found that the provision of monthly tax filing has increased textile businesses’ dependency on tax professionals, which increased business costs. Also, the GST system has made tax compliance easier and is user-friendly. However, tax refund-related issues are a significant factor that negatively impacts the ease of doing business post-GST.

Research limitations/implications
The findings of the research shall be helpful for the GST Council of India and policymakers to understand the problems faced by the textile businesses and cater to their problems.

Originality/value
To the best of the authors’ knowledge, this study is original as none of the available studies captures the perception of all the textile industry stakeholders, namely, manufacturers, wholesalers, retailers, consumers and tax professionals, on the GST system applying econometric techniques to validate the perceptions.
The older adult: physical activity considerations and learning to age in place
Authors: Carrick Ryan M. , Wadsworth Danielle 
Published: October 2023

Purpose
The purpose of this study is to investigate the transfer of learning among older adults and the importance of physical activity (PA) related to aging in place.

Design/methodology/approach
A mixed-methods approach examined 10 older adults aged 65–88, who were receiving occupational therapy and contemplating aging in place. Semistructured interviews determined participants' perceptions of aging in place and PA. Accelerometers assessed levels of PA over 14 days.

Findings
Interviews revealed that most participants were aware of the importance of PA but did not specify PA as being a primary contributor to continued independence with aging. Accelerometer data revealed that, on average, 96.7% of the day is spent in sedentary behavior.

Practical implications
Health-care professionals may ask the question, “What will my patient do with the information he or she has learned?” This study was useful to increase understanding of older adults’ learning, lifestyles and effects on aging independently.

Social implications
As older adults have true expectations of requirements for successful aging in place, realistic levels of PA and transfer of learning could improve the intended outcome of aging independently.

Originality/value
PA is often an overlooked factor for occupational engagement and aging in place and is novel to investigate in combination with interviews.
Constituting absence as reliability: The case of COVID‐19 response networks
Authors: Rice Rebecca M. 
Published: October 2023

AbstractHigh reliability organizations (HROs) are rare organizations that manage established technologies to avoid catastrophic errors. The concept of reliability, however, has become attractive to other organization types. This expansion creates scholarly questions about what reliability is outside of HROs. The COVID‐19 pandemic challenged new organizations to create reliability by also creating alternative meanings and practices of reliability that could adequately address an unknown, evolving health threat. This study draws on semistructured interviews and virtual ethnography during the first year of the COVID‐19 pandemic to examine how organizations communicatively defined reliability. The study finds that organizations engage in datafication of hazards to demonstrate they are performing reliably and proposes the practice of “evidencing reliability” as an important step in constituting reliability. However, datafication of hazards can also lead to skewed understandings of organizational performance and potential success biases.