bluuebunny/crossref_metadata_2025_split huggingface dataset:
Solutions to improve the quality of higher education services in crises using soft systems methodology
Authors: ramezani sajad , moshtani mohamadreza jokar , talebi davood , Dorri Behrouz 
Published: January 2024

Abstract
The education sector encountered serious problems and the quality improvement of higher education services stopped after the Covid-19 pandemic. After the peak period of this virus, it is required to predict the crisis and consider appropriate solutions to improve the quality of higher education services. Thus, this study aimed to provide some solutions to improve the quality of higher education services in crisis situations. The combination of soft systems methodology with hesitant fuzzy best-worst method (HFBWM) was used to encounter the research problem. Based on soft systems methodology, three general areas were presented to improve the quality of higher education services. Such areas included solutions related to support services, solutions related to social development and team spirit, and improvement solutions related to management and planning. Thus, several solutions were provided in each area for Shahid Beheshti University. Finally, the solutions were prioritised based on the HFBWM. The establishment of updated educational systems, implementation of a strategic operational plan to improve services, and scientific consensus to improve education were considered as the prioritised solutions to improve the quality of higher education services in crises at Shahid Beheshti University.
Numerical Analysis for a piezoelectric contact problem with long-memory and wear
Authors: Oultou Abderrahmane , Baiz Othmane , Benaissa Hicham 
Published: January 2024

Abstract
In this paper, we consider a new mathematical model that describes a frictional quasi-static contact between a piezoelectric body with a long memory effect and a foundation. The contact is described with the normal compliance condition with unilateral constraint and a version of Archard’s wear law. We introduce the model and prove its weak formulation, which is composed of a history-dependent variational equality and an integral equation. Using abstract history-dependent variational inequality and fixed point theorem, we show the existence and uniqueness solution of the model. In addition, we introduce a fully discrete scheme for the numerical solution of the problem, based on the finite element method to approximate the spatial derivative, and on the Euler scheme to discretize the time derivative. Finally, we derive the optimal-order error estimate under appropriate regularity hypotheses.
MSC Classification: 74D10 , 74F15 , 74G30 , 47J20 , 49J40 , 35K86 , 74M10 , 74S05
The Therapeutic Role of Hyperoside in Medial Meniscus Destabilization-Induced Osteoarthritis: A Study on Subchondral Bone Remodeling
Authors: Yang Hua , Chen BinWei , Tang YE , Liao QiYue , Zhang Zhen , Liu Wei , Liu Sheng-Yao 
Published: January 2024

Abstract
Background The process of subchondral bone remodelling plays an imperative role in the progressive development of OA. Hyperoside (Hyp) is a flavonoid, which has a wide range of pharmacological effects. This study aims to explore the effect of Hyp on the subchondral bone to elucidate the therapeutic role of Hyp in medial meniscus destabilization (DMM) induced OA.Methods Firstly, we conducted histological research(HE staining, Safranin-O/Fast Green and Toluidine blue staining, TRAP staining, IHC) and microCT to test the ability of Hyp on cartilage degeneration and abnormal subchondral microstructural changes in the DMM-induced osteoarthritic mouse model. Secondly, In the in vitro experiments, RAW264.7 cells were induced to osteoblasts in the presence of different concentrations of Hyp and osteoclasts were labelled by TRAP staining. MC3TC-E1 cells were used to perform osteoinduction experiments in Osteogenic Induction Media (OIM). Osteogenic activity was observed through Alizarin red S staining, and mineralisation activity was observed through ALP staining. Last, Finally, the effect of Hyp on NF-κB pathways was studied using Western blot and immunofluorescence.Results Hyp decreased cartilage degeneration and improved BV/TV and Tb.Th structural parameters. It also reduced the number of TRAP-positive osteoclasts, nestin cells, and osterix cells in the subchondral bone. Additionally, Hyp Inhibits osteoclast formation and enhanced alkaline phosphatase activity and mineralization. Furthermore, the NF-κB signalling pathway related to osteoclasts was inhibited.Conclusion These results indicate that Hyp has potential therapeutic value for OA by modulating osteoclastogenesis and osteoblastogenesis in the subchondral bone.
Elective elderly patients undergoing thoracoabdominal surgery in the post- anesthesia care unit are at risk for inadequate emergence, (hypoactive emergence and emergence with delirium). A Cross-Sectional study
Authors: Bayable Samuel Debas , Debas Simachew Amogne , Alle Yewlsew Fentie , Amberbir Wubet Dessie , Fetene Melaku Bantie 
Published: January 2024

Abstract
Background:- This study aimed to ascertain the prevalence and contributing variables of unsatisfactory emergence after general anesthetic service for elderly patients undergoing thoracoabdominal operations.
Method: - In 2022, a cross-sectional study was carried out between December and June. All consenting patients participate with written informed consent after receiving ethical approval. Data has been collected through personally conducting interviews and chart reviews during the pre- and post-operative periods. The descriptive statistics were determined using cross-tabulation or frequency and percentage. Bi-variable and multivariable logistic regression models were fitted to identify predictive variables that were linked to the outcome variable. For multivariable regression, P-values of 0.05 were used to assess statistical significance.
RESULTS; - According to the current study, 90.5% (87.4-93.3) of surgical patients under general anesthesia experienced a normal emergence; in contrast, 5.70 %( 3.6-8.2) and 3.90 %( 2.1-5.9) of instances experienced an emergence with delirium and hypoactivity, respectively. A greater risk for emerging delirium was independently linked to anxiety, smoking, substance misuse, anemia, surgical history within three months, hypertension, metoclopramide prophylaxis, thiopentone, and pain ≥4 upon PACU admission,whereas male sex and patients who had ketofol induction were linked to a decreased chance of inadequate emergence. In elderly patients undergoing elective thoracoabdominal surgery, hypothermia in PACU, ASA III, exercise tolerance test (MET<4), and halothane, were found to be independently linked to hypoactive emergence, whereas pethidine, fluid intake ≥2000 ml, blood loss ≥500 ml, surgical duration >2 hrs, and PONV requiring antiemetic were significant risk factors for inadequate emergence.
CONCLUSION: - Despite the fact that risk factors are preventable, inadequate emergence is a common complication in elderly thoraco-abdominal surgery that presents challenges for anesthetists and PACU staff. Among elderly patients having thoraco-abdominal surgery, hypoactive emergence was less frequent than emergence delirium.
Robot Assisted Ureteric Reconstruction Surgery Using Hugotm Ras Robotic Platform – a Single Centre Experience
Authors: Tyagi Vipin , Pisre Kunal , Tyagi Ankit , AGARWAL BIPUL , Agarwal Ankit 
Published: January 2024

Abstract
Introduction
Robotic surgery is now the mainstay option for many urological and gynaecological procedures. Different Robotic surgical platforms have been devised but the widespread use of these platforms have been slowed down by its huge cost, maintenance and exclusivity. This led to increased competition and commercialization of robotic platform and development of new novel platforms to overcome these hurdles. This is the first series of Robot –assisted ureteric reconstruction surgeries using the new Open console Hugo RAS Robotic system.
Material and methods
All patients presenting to hospital with ureteric abnormality between April 2023 to September 2023 (n=20) were included in the study. Out of 20 patients, 14 patients had pyeloplasty, 4 underwent ureteric re-implantation and 2 uretero-ureterostomy respectively. The primary outcome was to access the surgical settings (docking angles/docking time, trocar positioning, cart positioning) and feasibility of this novel robotic platform.
Results
The mean console time and docking time was 108.8 minutes (85-176) and 6 minutes (4 to 20) respectively. No major post-operative complication was recorded and the average hospital stay was 3 days.
Conclusion
This is the first series to show the feasibility of Hugo RAS in the setting of Robot assisted ureteric reconstruction surgeries. Open console system, new advanced patient safety features, flexible independent arms makes it an attractive option for many new budding surgeons and new specialities. These are preliminary results with limited sample size, however, further studies needed to confirm its long term safety and efficacy.
An Improved and Efficient Coercion-resistant Measure for Electronic Voting System
Authors: Chen Tzer-Long , Liu Chia-Hui , Ou Ya-Hui , Huang Yao-Min , Wu Zhen-Yu 
Published: January 2024

Abstract

The need of introducing advanced security methods to the e-voting system becomes necessary and urgent around the world since there are two existing and inevitable threats, which are bribery and coercion, in most proposed e-voting systems. So far, if a voter’s voting processes is monitored by a briber or coercer with the secure scheme that has been proposed can successfully stop bribery and coercion. However, the methods proposed in the past fail to enable voters to vote without violating their volition even after their voting secrets are leaked. In order to reach the goal, this study proposed a level-five secure e-voting system, which is the highest level by bringing in an extra setup phase. In short, we seek to protect the system even if the major secret is revealed, voters still can cast their votes according to their volition. This study applies cryptographic techniques to make sure that the voting systems are secure enough to enhance the chance of being adopted widely.
Changes in the Oropharyngeal Microbiome in Moderate-to-Severe Tobacco Dependence Before and After 30 Days of Smoking Cessation
Authors: Guo Guijun , cheng qingzhao , Li Chuntao , Zhang Yadi , Liu Ling , Liu Tong , Zhong Yong , Xiang Yaling , Liao Zehua , Zhang Jianqing 
Published: January 2024

Abstract
Smoking considerably changes the oral microbiota vital for maintaining oral health; this possibly results in the development of diseases. Therefore, to restore the healthy oral microbiota, smoking cessation is a beneficial strategy. However, at present, the relationship between smoking cessation duration and oral microbial recovery remains unclear, and previous studies have not undertaken self-comparisons before and after smoking cessation. In the present study, we evaluated 30 healthy adult men with moderate-to-severe tobacco dependence who willingly quit smoking. Oropharyngeal swab samples were collected before and on day 30 of smoking cessation (experimental group). Simultaneously, samples were collected once from 30 never-smokers (control group). Metagenomic next-generation sequencing revealed differences in the β-diversity and relative abundance of the oral microbial species in both groups. Furthermore, linear discriminant effect size analysis identified the top 10 dominant species, which primarily belonged to the phyla Actinobacteria, Bacteroidetes, Firmicutes, Proteobacteria, and Verrucomicrobia. From before to day 30 after cessation, oropharyngeal microbiota composition gradually increased in the experimental group; thereafter, it gradually became similar to the composition in the control group. There is significant heterogeneity in the oral microbiota between smokers and never-smokers. A 30-day smoking cessation intervention can initiate a restorative trend in the oral microbiota of smokers.
Wireless Network Resource Allocation for Video Transmission Based on Non-Orthogonal Multiple Access
Authors: Li Rongzhen , Xu Lei , Song Yinke , Wang Ping , Liu Wanli , Cai Zhicheng 
Published: January 2024

Abstract
In wireless networks, we study the downlink scenario of a non-orthogonal multiple access (NOMA) network based on scalable video coding techniques. The resource allocation problem based on wireless NOMA network is modeled as a mixed-integer nonlinear programming problem, which is subject to video coding characteristics, sub-channel capacity, system available power, and real-time requirements of wireless network. In order to solve the resource allocation problem of wireless NOMA network, three sub-problems are proposed, e.g., user grouping sub-problem, power allocation sub-problem, and video layer allocation sub-problem. Firstly, we propose an auction-based solution for the user grouping sub-problem. Then, for the power allocation sub-problem, we choose successive convex approximation and Lagrangian dual decomposition method. Finally, for the video layer allocation sub-problem, we propose a greedy strategy. Simulation experiments show that our proposed algorithms ensure the real-time and reliability requirements of the wireless network and also improve the quality of the video experience.
First record of genus Haritalodes Warren, 1890 (Lepidoptera: Crambidae: Spilomelinae) from Türkiye: Haritalodes derogata (Fabricius, 1775)
Authors: Sezen Kazım , Aydın Ebru Güney , Yıldız Hasret Simge , Yıldız İslam , Can Feza , Ghanbari Solmaz , Toprak Umut 
Published: January 2024

Abstract
The genus Haritalodes Warren, 1890 (Lepidoptera: Crambidae: Spilomelinae) is represented in the worldwide except in the Nearctic and Neotropical regions by eleven species. Haritalodes derogata (Fabricius, 1775) is the most widely distributed species in the genus Haritalodes Warren, 1890 and is known in the West Palaearctic region. In this study, morphological and molecular identification of the specicies by PCR of mitochondrial cytochrome oxidase region I (CO1) are given. This is the first record of the genus Haritalodes from Türkiye.
1D numerical simulations aimed to reproduce the operative conditions of a LOX/LCH4 engine demonstrator.
Authors: Romano Angelo , Ricci Daniele , Battista Francesco 
Published: January 2024

Abstract
The utilization of liquid oxygen/liquid methane couple (LOX/LCH4) as a potential candidate to substitute hypergolic propellants and hydrazine in the next future propulsion systems has arisen an increasing interest due to the advantages offered in terms of low environmental impact, re-usability, cooling capabilities and relatively high specific impulse. In this perspective, the Italian Aerospace Research Center manages the “HYPROB” research program, cofunded by the Italian Research and University Ministry, that has the objective to improve the national capabilities into developing engines, fed by hydrocarbons, that could be successfully applied as propulsion units for third stages of launchers for space exploration. The “HYPROB” program led to the realization of a LOX/LCH4 engine named “DEMO-0A”, a 30 kN thrust class demonstrator, technologically representative of a regenerative thrust chamber assembly of an expander engine. The present paper describes the results of the numerical simulations performed by means of the EcosimPro software, aimed at reproducing the operative conditions, both cold flow both firing, of the regenerative thrust chamber “DEMO-0A”. An assessment of the capabilities of the software in predicting the behaviour of the demonstrator by modelling it with a 1-D approach and by considering different wall heat exchange semiempirical correlations has been done by comparing numerical results and the available experimental data gathered during both cold flow both firing test campaigns.
The Impact of Tourism on Economic Growth in Tunisia: Application through ARDL Modelling
Authors: MTIRAOUI Abderraouf , Obeid Hassan 
Published: January 2024

Abstract
The objective of this work is the empirical investigation of the relationship between tourism and economic growth in Tunisia over the period from 1975 to 2018. Using control variables chosen during a reading of the theoretical and empirical review of the determinants of economic growth in the context of responding to the problem posed for the case of Tunisia. In the first step, it is appropriate to present the methodology of analysis that we will adapt in our study, where the identification of the theoretical and empirical bases combined with the specification of our empirical model occupies a place of honor. The second step consists in gathering the empirical results with the help of the ARDL modelling, the interpretations of this study in Short term (ST) as well as in Long term (LT) accompanied with some lessons for a possible development strategy of the tourist sector.
JEL classification : C23, O16.
Evaluation of Different Approaches to Define Expert Benchmark Scores for New Robotic Training Simulators Based on the Medtronic HUGOTM RAS Surgical Robot Experience
Authors: MS Mark Brentnall , Jr John Lenihan , BSc Chris Simmonds , Malpani Anand , Gargiuolo Antonio , Martino Martin , Levy Jeffrey S 
Published: January 2024

Abstract
Introduction
New robot-assisted surgery platforms being developed will be required to have proficiency-based simulation training available. Scoring methodologies and performance feedback for trainees are not consistent across all simulator platforms. This paper compares methods used to determine proficiency-based scoring thresholds (a.k.a. benchmarks) for the new Medtronic Hugo™ RAS robotic simulator.
Methods
Nine experienced robotic surgeons from multiple disciplines performed the 49 skills exercises 5 times each. The data was analyzed 3 different ways: (1) include all data collected, (2) exclude first sessions, (3) exclude outliers. Eliminating the first session discounts becoming familiar with the exercise. Discounting outliers allows for removal of potentially erroneous data that may be due to technical issues, unexpected distractions, etc. Outliers were identified using a common statistical technique involving the interquartile range of the data. Using each method above, the mean and standard deviations were calculated, and the benchmark was set at a value of 1 standard deviation above the mean.
Results
In comparison to including all the data, when outliers are excluded, fewer data points are removed than excluding just first sessions, and the metric benchmarks are made more difficult by an average of 11%. When first sessions are excluded, the metric benchmarks are made easier by an average of about 2%.
Conclusion
In comparison with benchmarks calculated using all data points, excluding outliers resulted in the biggest change making the benchmarks more challenging. We determined that this method provided the best representation of the data. These benchmarks should be validated with future clinical training studies.
COL5A1 promotes triple-negative breast cancer progression by activating tumor cell-macrophage crosstalk
Authors: Yang Qifeng , Chen Xi , Ma Chenao , Li Yaming , Liang Yiran , Chen Tong , Han Dianwen , Luo Dan , Zhang Ning , Zhao Wenjing , Wang Lijuan 
Published: January 2024

Abstract
Triple-negative breast cancer (TNBC) is a highly aggressive subtype of breast cancer. Despite the reported interplay between tumors and tumor-associated macrophages (TAM) in fostering drug resistance and disease progression, the underlying mechanisms governing these interactions remain elusive. Here, it was found an upregulation of Collagen type V alpha 1 (COL5A1) in TNBC tissues, particularly in chemoresistant samples, correlating with an unfavorable prognosis. Functional assays demonstrated that COL5A1 played a pivotal role in fostering cancer growth, metastasis, and doxorubicin (DOX) resistance both in vitro and in vivo. In addition, the cytokine IL-6 produced by COL5A1 overexpressing TNBC cells facilitated M2 macrophage polarization. Reciprocally, TGFβ from M2 macrophages promoted TNBC DOX resistance through mediating the TGFβ/smad3/COL5A1 signaling pathway, therefore constituting a feed-back loop between TNBC cells and macrophages. Mechanistically, COL5A1 was found to interact with TGM2, inhibiting its K48-linked ubiquitination-mediated degradation. This led to an enhanced chemoresistance and increased secretion of IL-6. In summary, these findings unveiled that the upregulation of COL5A1 held significant potential in driving TNBC progression and chemoresistance by modulating macrophage polarization. This supports the proposition that targeting COL5A1 could emerge as an effective strategy against TNBC.
Correlation between intestinal CRE colonization and subsequent systemic infection in hospitalized patients
Authors: Xiao Yuanyuan , Duan Juping , Tan Caixia , Zou Ju , Chen Siyao , Liu Ting , Zhang Lina , Chen Xin , Xu Yajing , Li Yuanyuan , Wu Anhua , Li Chunhui 
Published: January 2024

Abstract
Purpose
It is generally believed that Carbapenem-resistant Enterobacteriaceae (CRE) colonization is primarily responsible for subsequent systemic infection in humans. In China, the specific situation of CRE colonization and subsequent systemic infection in hospitalized patients necessitates further exploration.
Methods
We retrospectively analyzed data of intestinal CRE colonization inpatients at Xiangya Hospital, Central South University, regarding demography, clinical and pathogenic characteristics, treatment, and outcome. A risk prediction model for subsequent CRE infection was established and externally validated.
Results
In total, 839 intestinal CRE colonization samples from inpatients were included. Finally, 317 cases of intestinal CRE colonization were enrolled, 25.9% of whom developed systemic infections. The subsequent CRE infection rates of CRKP and CREC were 27.0% and 32.3%, respectively. The incidence of subsequent CRE infection in the respiratory medicine department, hematology department, and intensive care unit (ICU) was 26.7%, 21.8%, and 45.0%, respectively. Taking probiotics and the combined oral and intravenous administration of antibiotics were the protective factors for the subsequent infection of intestinal CRE colonization, while liver disease, agranulocytosis ≥ 7 days, hypoproteinemia, invasive respiratory assisted ventilation, history of surgery/trauma in the past 3 months, and use of antifungal drugs were the independent risk factors.
Conclusions
CRE infection after intestinal CRE colonization in inpatients can significantly prolong the length of hospital stay and increase total medical costs. The CRE infection group exhibited poor efficacy and high mortality. Thus, the established risk prediction model for intestinal infection after CRE colonization in hospitalized patients has a good prediction efficacy for high-risk departments.