bluuebunny/crossref_metadata_2025_split huggingface dataset:
Emotional dysregulation and its pathways to suicidality in a community-based sample of adolescents
Authors: Mittermeier Sabrina , Seidel Alexandra , Scheiner Christin , Kleindienst Nikolaus , Romanos Marcel , Buerger Arne 
Published: January 2024

Abstract
Objective
Effective suicide prevention for adolescents is urgently needed but difficult, as suicide models lack a focus on age-specific influencing factors such as emotional dysregulation. Moreover, examined predictors often do not specifically consider the contribution to the severity of suicidality.
To determine which adolescents are at high risk of more severe suicidality, we examined the association between emotional dysregulation and severity of suicidality directly as well as indirectly via depressiveness and nonsuicidal self-injury.

Method
Adolescents from 18 high schools in Bavaria were included in this cross-sectional and questionnaire-based study as part of a larger prevention study. Data were collected between November 2021 and March 2022 and were analyzed from January 2023 to April 2023.
Students in the 6th or 7th grade of high school (11–14 years) were eligible to participate. A total of 2350 adolescents were surveyed and data from 2117 students were used for the analyses after excluding incomplete data sets. Our main outcome variable was severity of suicidality (Paykel Suicide Scale, PSS). Additionally, we assessed emotional dysregulation (Difficulties in Emotion Regulation Scale, DERS-SF), depressiveness (Patient Health Questionnaire, PHQ-9) and nonsuicidal self-injury (Deliberate Self-Harm Inventory, DSHI).

Results
In total, 2117 adolescents (51.6% female; mean age, 12.31 years [standard deviation: 0.67]) were included in the structural equation model (SEM). Due to a clear gender-specific influence, the model was calculated separately for male and female adolescents. For male adolescents, there was a significant indirect association between emotional dysregulation and severity of suicidality, mediated by depressiveness (β = 0.15, SE = .03, p = .008). For female adolescents, there was a significant direct path from emotional dysregulation to severity of suicidality and also indirect paths via depressiveness (β = 0.12, SE = .05, p = 0.02) and NSSI (β = 0.18, SE = .04, p < .001).

Conclusions
Our results suggest that gender-related risk markers in 11–14-year-olds need to be included in future suicide models to increase their predictive power. According to our findings, early detection and prevention interventions based on emotion regulation skills might be enhanced by including gender-specific adjustments for the co-occurrence of emotional dysregulation, depressiveness, and nonsuicidal self-injury in girls and the co-occurrence of emotional dysregulation and depressiveness in boys.
Young adults looking back at their experiences of treatment and care for nonsuicidal self-injury during adolescence: a qualitative study
Authors: Andersson H , Svensson E , Magnusson A , Holmqvist R , Zetterqvist M 
Published: January 2024

Abstract
Background
Nonsuicidal self-injury (NSSI) is associated with stigma, and negative attitudes among healthcare professionals toward NSSI have been reported. A person-centered approach that focuses on how individuals with lived experience of NSSI perceive the treatment and care they receive is invaluable in reducing barriers to help-seeking and improving treatment and mental healthcare services. The aim of the current qualitative study was to explore the perceptions of young adults when they look back upon their experiences of psychiatric treatment for NSSI during adolescence.

Methods
Twenty-six individuals with lived experience of NSSI who were in contact with child and adolescent psychiatry during adolescence were interviewed. The interviews were analyzed using thematic analysis.

Results
Three main themes were developed: Changed perceptions in retrospect, The importance of a collaborative conceptualization and Lasting impression of the relationship. Participants’ perception of themselves as well as the treatment changed over time. The importance of a joint understanding of NSSI and an agreed-upon treatment focus was emphasized. The relationship to the mental health professionals, and experiences of how NSSI was communicated, were salient several years later.

Conclusions
Healthcare professionals need to communicate about NSSI in a respectful manner and include the perspective of the adolescent with lived experience of NSSI in a joint conceptualization of NSSI and treatment focus.
Sugar and blood: the nutritional priorities of the dengue vector, Aedes aegypti
Authors: Tenywa Frank Chelestino , Musa Jeremiah John , Musiba Revocatus Musyangi , Swai Johnson Kyeba , Mpelepele Ahmad Bakar , Okumu Fredros Oketch , Maia Marta Ferreira 
Published: January 2024

Abstract
Background
Sugar-feeding behaviour is essential for mosquito survival and reproduction, and has been exploited to develop new control strategies, such as the attractive targeted sugar baits (ATSB). This study examined the sugar-feeding habits of the dengue vector, Aedes aegypti, in semi-field conditions to determine the optimal timing (age) of sugar meals and whether the availability of sugar sources could affect blood-feeding by these mosquitoes.

Methods
A series of paired-choice assays were conducted in which mosquitoes were allowed to choose between a sugar meal or a blood meal directly from a rabbit. Female 1-day-old mosquitoes were given meal choices in cages I–V and observed for feeding choice in only one cage every day for 5 days starting with cages I to V. The preference of Ae. aegypti to feed on sugar or blood and the effect of sugar source availability on blood-feeding was assessed at different chronological and physiological ages.

Results
In the first 5 days post-emergence, there was no significant difference in mosquito preference for sugar or blood meals. However, after the first gonotrophic cycle, they had a greater preference for blood over sugar (odds ratio, OR [95% confidence interval, CI] = 9.4 [6.7–13.0]; P < 0.001). Nulliparous Ae. aegypti females (≤ 5-day-old mosquitoes) were less likely to blood-feed if both sugar and blood sources were concurrently available (OR = 0.06 [0.02–0.16]; P < 0.001).

Conclusions
Newly emerged females of Ae. aegypti mosquitoes were equally likely to choose a sugar meal or a blood meal. However, after the first gonotrophic cycle, they had a greater preference for blood over sugar. Additionally, nulliparous female mosquitoes were less likely to blood-feed when both sugar and blood sources were available. These findings provide insights into the sugar-feeding behaviour of Ae. aegypti and can inform the development and optimization of new control strategies such as using ATSB.

Graphical Abstract
Improving the thermostability of Pseudoalteromonas Porphyrae κ-carrageenase by rational design and MD simulation
Authors: Sang Yuyan , Huang Xiaoyi , Li Hebin , Hong Tao , Zheng Mingjing , Li Zhipeng , Jiang Zedong , Ni Hui , Li Qingbiao , Zhu Yanbing 
Published: January 2024

AbstractThe industrial applications of the κ-carrageenases have been restricted by their poor thermostability. In this study, based on the folding free energy change (ΔΔG) and the flexibility analysis using molecular dynamics (MD) simulation for the alkaline κ-carrageenase KCgCD from Pseudoalteromonas porphyrae (WT), the mutant S190R was identified with improved thermostability. After incubation at 50 °C for 30 min, the residual activity of S190R was 63.7%, 25.7% higher than that of WT. The Tm values determined by differential scanning calorimetry were 66.2 °C and 64.4 °C for S190R and WT, respectively. The optimal temperature of S190R was 10 °C higher than that of WT. The κ-carrageenan hydrolysates produced by S190R showed higher xanthine oxidase inhibitory activity compared with the untreated κ-carrageenan. MD simulation analysis of S190R showed that the residues (V186–M194 and P196–G197) in F5 and the key residue R150 in F3 displayed the decreased flexibility, and residues of T169–N173 near the catalytic center displayed the increased flexibility. These changed flexibilities might be the reasons for the improved thermostability of mutant S190R. This study provides a useful rational design strategy of combination of ΔΔG calculation and MD simulation to improve the κ-carrageenase’s thermostability for its better industrial applications.
Insurtech in Europe: identifying the top investment priorities for driving innovation
Authors: Eti Serkan , Dinçer Hasan , Meral Hasan , Yüksel Serhat , Gökalp Yaşar 
Published: January 2024

AbstractThe purpose of this study is to determine the essential indicators to improve insurtech systems and select the most critical alternative to increase insurtech-based investments in European countries. A novel fuzzy decision-making model is generated by integrating entropy and additive ratio assessment (ARAS) techniques with spherical fuzzy sets. First, the indicators are weighted using spherical fuzzy entropy. Then, the alternatives are ranked using spherical fuzzy ARAS. The alternatives are also ranked with the spherical fuzzy technique for order of preference by similarity to the ideal solution methodology. The main contribution of this study is that it would help investors to take the right actions to increase the performance of insurtech investments without incurring high costs. Another important novelty is that a new fuzzy decision-making model is proposed to solve this problem. The results of the two models are quite similar, proving the validity and coherency of the findings. It is found that pricing is the most critical factor that affects the performance of insurtech investments. Insurtech companies are required to make accurate pricing by conducting risk analyses to increase their profits and minimize their risks. Additionally, according to the ranking results, big data are the most appropriate way to improve the performance of insurtech investments in Europe. Big data analytics helps companies learn more about the behavior of their customers. By analyzing data about their customers’ past transactions, companies can provide more convenient services to them. This would increase customer satisfaction and enable companies to achieve long-term customer loyalty.
The Impact of diet on the digestive, cardiovascular and immune systems
Authors: Kobierecki Mateusz , Kwaśniewska Oliwia , Misiak Jakub , Urbaś Michał , Ojdana Miłosz , Demianenko Yehor , Czekaj Oliwia , Kościołek Aleksandra , Kościołek Dawid , Kępczyk Martyna 
Published: January 2024

INTRODUCTION AND AIM OF WORK
One of the key factors shaping human health is diet. It serves as the foundation for the functioning of cells, organs, and the entire body. Properly chosen food has an impact, among other things, on the functioning of the immune, digestive, and cardiovascular systems.

MATERIALS AND METHODS
The objective of this study is to analyze the changes in the functioning of the cardiovascular, digestive, and immune systems through the application of different dietary approaches. For this purpose, an original questionnaire was developed. The questionnaire was distributed via social media (Telegram platform) in August 2023 among the population of Ukraine.

RESULTS
We collected a total of 94 surveys, with an average participant age of 26 years. A similar number of participants indicated consuming meals 3 times, 4 times, or 5 times a day. These were 23 individuals (24.47%), 25 individuals (26.6%), and 21 individuals (22.3%) respectively. The analysis of correlations revealed a negative correlation between the frequency of meal consumption and the frequency of infections (r = -0.21, p = 0.035). A significant relationship was also observed between body weight and the frequency of meal consumption (r = 0.34, p < 0.001). However, no significant relationship was found between following a special diet and body weight (p > 0.05).

CONCLUSIONS
The collected results suggest a connection between dietary habits and the frequency of infections as well as body weight. Interestingly, this relationship was related specifically to the frequency of meal consumption and was not linked to the intake of specific food groups. The obtained results highlight the significance of regular meal consumption in maintaining a healthy body weight and reducing the frequency of infections.
Examination of novel diagnostic approaches and contemporary strategies for preventing acute mountain sickness
Authors: Olejarz Zuzanna , Nowak Karolina , Drygała Zuzanna , Wyrwał Julia , Zielińska Zuzanna , Słowik Magdalena , Nowak Karolina , Nieć Maria , Gierlach Katarzyna , Krasuska Martyna 
Published: January 2024

Introduction and purpose: Acute mountain sickness is caused by hypoxia, of which the brain is the most sensitive. The frequency of occurrence at altitudes above 2500 m above sea level may reach up to 75% of travelers. Prevention of altitude sickness mainly concerns the travel plan and pharmacology. Our study aimed to assess the current literature on altitude sickness, and discuss the possible pathophysiology, epidemiology, and symptoms. Moreover, we underline new guidelines for the treatment, prevention, and diagnosis of altitude sickness in the context of the last guidelines and research. We conducted a PubMed literature review using keywords like "mountaineering sickness" and "altitude sickness". All article types were taken into account: clinical trial, meta-analysis, case report, case series, systematic review, randomized controlled trial, observational study, clinical study, books, and documents in the last 5 years.A brief description of the state of knowledge: In recent years, there has been a surge in the accessibility and popularity of high-altitude tourism, emphasizing the need to disseminate information about altitude sickness among travelers. This heightened accessibility has sparked a push for comprehensive research and viable solutions, aiming to address the ramifications of the increased risk associated with such endeavors. Furthermore, there's a growing call for additional research focusing on the unique medical demands posed by tourist excursions and extreme expeditions. Conclusions:It underscores the necessity for healthcare professionals equipped with specialized knowledge and expertise in both preventing and treating medical conditions arising in exceptional circumstances.
The influence of lipoproteina(a) on cardio-vascular diseases
Authors: Maj-Dziedzic Monika , Brzozowska Anna , Sikora Marcelina , Zarzycka Marta , Plewniok Ines , Dubiel Jeremiasz , Maj Adrian , Śmietana Greta , Warno Martyna , Kozik Wiktor 
Published: January 2024

Introduction
The current evidence from 2022 published by European Atherosclerosis Society brings the importance of the level of lipoprotein(a) and its influence on the human health. Especially atherosclerotic cardio-vascular events such as myocardial infarction, heart failure, stroke, atherosclerosis are taken into account. They prove, that the associations between the level of Lp(a) is linear with the occurrence of cardio-vascular events. High level of Lp(a), may contribute to the aortic stenosis, cause has pro-inflammatory and pro-atherosclerotic properties. The newest finding demonstrate that Lp(a) has no link with venous thrombosis. Nonetheless, very low level of may contribute with type 2 diabetes.
It is recommended to measure the level of lipoprotein(a) at least once in adults to search the patients with higher value than norm. Even at low level of LDL, high Lp(a) is a risk factor for ASCVD. It brings the clinical importance of early detection of potential cardio-vascular diseases and introduction of management. The newest statement form EAS also brings promising possibilities due to specific Lp(a)-lowering therapies is in phase II/III trials.

Aim of the study
The following paper aims to present a review of the current knowledge about the influence of the level of Lp(a) on cardio-vascular disease and seeks to enhance knowledge and promote effective management of this prevalent condition.
The primary goal is to promote the current problem to health care workers with up-to-date information to facilitate early recognition of cardiovascular events.

Materials and methods
This article presents the current state of knowledge of lipoprotein(a) found in various scientific articles.
The following English keywords and its Polish equivalents were used to search Google Scholar's medical databases: lipoprotein(a), cardio-vascular disease, cardiovascular risk, aortic stenosis. The articles most pertinent to the subject have been chosen.
Congenital toxoplasmosis: potential outcomes and therapeutic challenges - a complex case report of the newborn with treatment-resistant manifestations
Authors: Kowalczyk Emilia , Koziej Sylwia , Niemczuk Martyna , Jasiuk Adrianna , Wiekiera Mateusz 
Published: January 2024

Introduction and purpose
Toxoplasmosis, a prevalent parasitic infection caused by Toxoplasma gondii, impacts approximately one-third of the global population. Among congenital infections, Congenital Toxoplasmosis (CT) ranks second only to CMV infection in neonates. The severity of fetal and neonatal clinical manifestations depends on factors such as gestational age during infection, parasite load, infectious strain virulence, and maternal immune status. The organogenesis stage in the second trimester is identified as the critical period (10th-24th gestational weeks). Fetal CT may present with ultrasound-detected abnormalities, including intracranial calcifications, microcephaly, hydrocephalus, ascites, hepatosplenomegaly or severe intrauterine growth restriction. Even in the absence of symptoms at birth, CT can lead to long-term consequences such as hydrocephalus, seizures, and cognitive, auditory, and visual impairments.
The aim of this study is to present a clinical case of a patient with CT infection complicated by treatment-resistant hydrocephalus and neurological symptoms, including muscle tone disturbances and seizures.

Conclusion
The significance of screening tests cannot be overstated, as early intervention is crucial to prevent enduring complications. Routine counseling for pregnant women is imperative to raise awareness about Toxoplasma gondii infection, empowering them to adopt necessary preventive measures. Additionally, further research is warranted to assess the efficacy of diverse treatment protocols, the risk of adverse effects, and the effectiveness of emerging therapeutic agents.
Springing to Life: Unveiling the Transformative Effects of Trampoline Bouncing on Human Health
Authors: Bereza Dawid , Sokołowska Katarzyna , Kulak Maria , Moreau Igor , Polańska Paulina , Lang Miriam , Woch Barbara 
Published: January 2024

Introduction and Objective: In the modern era, where non-communicable diseases account for 74% of deaths, physical activity plays a crucial role in reducing mortality rates, particularly from cardiovascular causes. This article aims to assess the benefits and risks of trampoline bouncing as an exercise modality.
State of Knowledge: Scientific evidence predominantly focuses on rebounding-related injuries, overshadowing the relatively underexplored benefits of trampolining. Cardiovascular advantages, including increased VO2max, are notable, with mini-trampoline exercise proving more effective than traditional running. Trampolining exhibits the potential to reduce BMI and weight, impacting cardiovascular risk factors while contributing to bone strength and mental well-being. Positive outcomes are suggested for specific groups, such as Parkinson's patients and children with disabilities.
Summary: Trampoline rebounding, particularly with mini-trampolines, presents an enjoyable exercise form with significant health benefits, encompassing enhanced cardiovascular endurance, improved balance, and positive effects on bone structure and mental well-being. Despite prevalent injuries associated with trampoline use, the article highlights effective preventive measures. In conclusion, trampoline bouncing holds promise as a valuable component of a healthy lifestyle, provided adequate precautions are taken to mitigate associated risks.
Foto Anak-Anak dalam Bingkai Tragedi Kemanusiaan; Studi Struktur Visual Foto Pemenang World Press Photography 1997 & 2019
Authors: Darmawan Yurif Setya 
Published: January 2024

Children are often helpless in the face of harsh life situations. In the photo media children are described as "weak" and become objects of representation as victims of war conditions. Photos with children as the main object are considered capable of evoking the emotions of the audience with their own power. This was proven when the 1997 and 2019 World Press Photography awards were won by photographs whose main objects were children in war situations or other unpleasant conditions. A good photo can evoke emotion, the punctum can be studied for its structure (syntag) so that it can be seen why the photo is interesting. In fact, photos are always the choice of objects framed by the photographer. Photo objects are arranged and arranged in such a way as to evoke the emotions of anyone who sees them.
Keywords: children, framing, World Press Photography, photo structure, punctum
Closed Loop Control of DSMST Converter for Ev Applications
Authors: Jeetender Vemula Et al. 
Published: January 2024

Transformerless step-down and step-up DC-DC topologies are currently extensively employed in a variety of applications. A positive output voltage SEPIC-type DC-DC converter without a transformer is proposed in this article. This configuration has the benefit of input continuous current over the traditional buck-boost converter, making it better suited for use with electric vehicles. Moreover, it has an increase in gain that is quadratic of the voltage gain of a standard topology. Also, the suggested converter has a constant current output, which decreases the output voltage ripple and reduces the current stress on the converter's output capacitor. As a result, this converter can generate an extensive range of voltages with less input and output ripples. In addition, closed loop control of DSMST converter is presented in the paper using PI control Ziegler- Nichols method. In the end, simulation findings are shown to support the converter's closed loop study.
Tathbiiq Wasilah al-Ta’liim Puzzle Envelope fi Ta’allum al-Lughoh al-Arabiyyah li Thullab Madrasah Budi Mulia al-Mutawassithoh al-Tsaaniyah Yogyakarta
Authors: Rahmawati Fitra Awalia , Amaliza Fhira Rukti 
Published: January 2024

المدرسة الثانوية بودي موليا دوا هي المدرسة الإسلامية التي يستخدم اللغتين الإندونيسية والإنجليزية في التعليم، وهي إحدى المدارس العالمية في إندونيسيا. ولها مجموعة متنوعة من المواد الدراسة، ولكن تعليم اللغة العربية في هذه المدرسة بدأ في عام 2022، ولم توجد استراتيجية أي طريقة التعليم المشوقة لتعليم اللغة العربية. بسبب هذه المشكلة، يحصل بعض الطلاب عدم اهتمام عند عملية التعلم بالنظر على النتائج أقل من النتائج المعدل. لذلك حاولت الباحثة تقديم وسيلة تعليم لغز المغلف التي يمكن أن تجعل الطلاب أكثر اهتمامًا وتسهل على الطلاب فهم تعلم اللغة العربية وتشجّع المدرسة في تطبيق طرق التعلم المبتكرة. مؤسسا على المشكلات السابقة يهدف هذا البحث إلى معرفة فعالية تطبيق وسيلة التعليم لغز المغلف على نتائج تعلم اللغة العربية لطلاب الصف الثامن بالمدرسة بودي موليا دوا يوجياكارتا 2022-2023. إن نوع البحث المستخدم في هذا البحث هو بحث كمي تجريبي، وأخذت الباحثة بنوع تصميمه على شكل التجربة الحقيقة ومنهج الفرقة المنظمة حيث يتم أخد اختيار أعضاء الفصل التجريبي والفصل الضابط بشكل عشوائي. وطريقة جمع البيانات المستخدمة في هذا البحث هي المقابلات والاختبارات والتوثيق. ويتم إجراء تحليل البيانات باستخدام اختبار غير بارمترا بالاختبار الطبيعي والاختبار التجانس والاختبار الفرضي Mann Whitney ببرنامج SPSS 22 لأن البيانات غير طبيعية. من خلال هذا البحث، استنتجت الباحثة أن تنفيذ وسيلة التعليم لغز المغلف في تعليم اللغة العربية وهي 0.000 كانت أصغر من 0.05. فاستنتجت الباحثة أن H0 مرفوض وHaمقبول، من هذه المعلومات تتبين لنا بأن هناك فرق بين نتائج تعلم اللغة العربية في الفصل التجريبي والفصل الضابط. من هذه النتائج، استنتج أن وسيلة التعليم لغز المغلف كانت فعالة في نتائج تعلم اللغة العربية لطلاب الصف الثامن بالمدرسة الثانوية بودي موليا دُوا يوجياكارتا 2022-2023.