bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessment of COVID-19 vaccine uptake and associated factors among healthcare workers in selected health facilities of the Somali Region, Eastern Ethiopia: a cross-sectional study conducted in 2021
Authors: Wassihun Yosef , Berhe Trhas Tadesse , Melesse Addisalem , Wolde Maereg , Sharma Rachana , Mon Hnin Su , Simireta Tesfaye , Addisu Hailemariam 
Published: February 2024

BackgroundThe global COVID-19 pandemic poses substantial health challenges. Vaccination is key in preventing COVID-19, particularly among healthcare workers (HCWs), essential in curbing the pandemic. Despite global data on HCWs’ vaccine uptake, information about vaccination among HCWs in the Somali Region, Ethiopia, is scarce.ObjectiveThis study aimed to assess COVID-19 uptake and determinant factors for HCWs in the Somali Region, Eastern Ethiopia, 2021.MethodsA facility-based cross-sectional study was conducted from 20 October 2021 to 30 October 2021, involving 440 systematically selected participants. Data were collected through self-administered questionnaires, cleaned, coded and entered into Epi Info software (V.3.5.1; CDC). Subsequently, the data were exported to Stata software (V14.1) for analysis. Descriptive statistics were used to report frequency, percentage, mean and SD. Multiple logistic regression analysis was performed to predict the relationship between independent and dependent variables. In the final model, statistical significance was determined with a 95% CI and a p<0.05.ResultA total of 427 HCWs were involved in this study. About 192 (45%) of the participants had a history of test for COVID-19 and 64 (15%) were tested positive for COVID-19 infection. Three hundred and three (76%) at 95% CI (70.3% to 80.6%) of HCWs got at least one dose of the COVID-19 vaccine. Other professions such as paramedics, environmental health and pharmacist were less likely to get COVID-19 vaccine than nurses (adjusted OR, AOR 0.2; 95% CI (0.06 to 0.53)). Participants who were concerned about the availability of the COVID-19 vaccine were less likely to receive it than individuals who were not concerned (AOR 0.01; 95% CI (0.002 to 0.052)).ConclusionThe vaccination uptake among HCWs in the region was relatively low, with the type of profession and concerns about vaccine availability being significant factors affecting the uptake.
Paravertebral and erector spinae plane blocks decrease length of stay compared with local infiltration analgesia in autologous breast reconstruction
Authors: Ayyala Haripriya S , Assel Melissa , Aloise Joseph , Serafin Joanna , Tan Kay See , Mehta Meghana , Puttanniah Vinay , McCormick Patrick , Malhotra Vivek , Vickers Andrew , Matros Evan , Lin Emily 
Published: February 2024

BackgroundAutologous breast reconstruction is associated with significant pain impeding early recovery. Our objective was to evaluate the impact of replacing surgeon-administered local infiltration with preoperative paravertebral (PVB) and erector spinae plane (ESP) blocks for latissimus dorsi myocutaneous flap reconstruction.MethodsPatients who underwent mastectomy with latissimus flap reconstruction from 2018 to 2022 were included in three groups: local infiltration, PVB, and ESP blocks. Block effect on postoperative length of stay (LOS) and the association between block status and pain, opioid consumption, time to first analgesic, and postoperative antiemetic administration were assessed.Results122 patients met the inclusion criteria for this retrospective cohort study: no block (n=72), PVB (n=26), and ESP (n=24). On adjusted analysis, those who received a PVB block had a 20-hour shorter postoperative stay (95% CI 11 to 30; p<0.001); those who received ESP had a 24-hour (95% CI 15 to 34; p<0.001) shorter postoperative stay compared with the no block group, respectively. Using either block was associated with a reduction in intraoperative opioids (23 morphine milligram equivalents (MME)), 95% CI 14 to 31, p<0.001; ESP versus no block: 23 MME, 95% CI 14 to 32, p<0.001).ConclusionsReplacing surgical infiltration with PVB and ESP blocks for autologous breast reconstruction reduces LOS. The comparable reduction in LOS suggests that ESP may be a viable alternative to PVB in patients undergoing latissimus flap breast reconstruction following mastectomy. Further research should investigate whether ESP or PVB have better patient outcomes in complex breast reconstruction.
Longitudinal associations between body mass index and changes in disease activity and radiographic progression in rheumatoid arthritis patients treated with infliximab
Authors: Burkard Theresa , Vallejo-Yagüe Enriqueta , Lauper Kim , Finckh Axel , Hügle Thomas , Burden Andrea M 
Published: February 2024

ObjectivesTreatment response is worse in obese patients with rheumatoid arthritis (RA), including patients on weight-adjusted therapies like infliximab. We aimed to assess the association between body mass index (BMI) and changes in RA disease activity and radiographic progression over time.MethodsWe included infliximab users with an RA diagnosis in the Swiss Clinical Quality Management in Rheumatic Diseases registry (1997–2020). Two cohorts were defined: (1) starting from their first BMI measurement or disease activity score (DAS28-esr), and (2) from their first BMI measurement or radiographic assessment (Rau score). We evaluated the coefficient and 95% CI of BMI with changes in mean DAS28-esr (cohort 1) and mean Rau scores (a structural joint damage score, cohort 2) using generalised estimation equations, overall and stratified by BMI categories.ResultsCohort 1 comprised 412 patients (74% women, mean age 53 years, mean BMI 25). We observed no change in mean DAS28-esr with increasing BMI overall (adjusted coefficient: 0.00, 95% CI −0.02 to 0.02), or in BMI categories. Cohort 2 comprised 187 patients highly alike to those in cohort 1. We observed a significant decrease of 1.05 in mean Rau scores for every increase in BMI unit (adjusted coefficient: −1.05, 95% CI −1.92 to −0.19). Results remained statistically non-significant across BMI categories.ConclusionsOur longitudinal investigation suggests that BMI increase may not lead to changes in DAS28-esr in patients receiving infliximab, despite the weight-adapted dose. Yet, there may be a decrease in erosions with increasing weight non-limited to obese patients.
Bilateral effect of acupuncture on cerebrum and cerebellum in ischaemic stroke patients with hemiparesis: a randomised clinical and neuroimaging trial
Authors: Chen Tianzhu , Chen Tianyan , Zhang Yong , Wu Kang , Zou Yihuai 
Published: February 2024

Background
Acupuncture involving the limb region may be effective for stroke rehabilitation clinically, but the visualised and explanatory evidence is limited. Our objectives were to assess the specific effects of acupuncture for ischaemic stroke (IS) patients with hemiparesis and investigate its therapy-driven modification in functional connectivity.

Methods
IS patients were randomly assigned (2:1) to receive 10 sessions of hand-foot 12 needles acupuncture (HA, n=30) or non-acupoint (NA) acupuncture (n=16), enrolling gender-matched and age-matched healthy controls (HCs, n=34). The clinical outcomes were the improved Fugl-Meyer Assessment scores including upper and lower extremity (ΔFM, ΔFM-UE, ΔFM-LE). The neuroimaging outcome was voxel-mirrored homotopic connectivity (VMHC). Static and dynamic functional connectivity (sFC, DFC) analyses were used to study the neuroplasticity reorganisation.

Results

46 ISs (mean(SD) age, 59.37 (11.36) years) and 34 HCs (mean(SD) age, 52.88 (9.69) years) were included in the per-protocol analysis of clinical and neuroimaging. In clinical, ΔFM scores were 5.00 in HA group and 2.50 in NA group, with a dual correlation between ΔFM and ΔVMHC (angular: r=0.696, p=0.000; cerebellum: r=−0.716, p=0.000) fitting the linear regression model (R
2
=0.828). In neuroimaging, ISs demonstrated decreased VMHC in bilateral postcentral gyrus and cerebellum (Gaussian random field, GRF corrected, voxel p<0.001, cluster p<0.05), which fitted the logistic regression model (AUC=0.8413, accuracy=0.7500). Following acupuncture, VMHC in bilateral superior frontal gyrus orbital part was increased with cerebro-cerebellar changes, involving higher sFC between ipsilesional superior frontal gyrus orbital part and the contralesional orbitofrontal cortex as well as cerebellum (GRF corrected, voxel p<0.001, cluster p<0.05). The coefficient of variation of VMHC was decreased in bilateral posterior cingulate gyrus (PPC) locally (GRF corrected, voxel p<0.001, cluster p<0.05), with integration states transforming into segregation states overall (p<0.05). There was no acupuncture-related adverse event.

Conclusions
The randomised clinical and neuroimaging trial demonstrated acupuncture could promote the motor recovery and modified cerebro-cerebellar VMHC via bilateral static and dynamic reorganisations for IS patients with hemiparesis.
Using k-means assistant event selection strategy to study anomalous quartic gauge couplings at muon colliders
Authors: Zhang Shuai , Yang Ji-Chong , Guo Yu-Chen 
Published: February 2024

AbstractThe search for new physics beyond the Standard Model is one of the central problems of current high energy physics interest. As the luminosities of current and near-future colliders continue to increase, the search for new physics has increased the requirements for processing large amounts of data. Meanwhile, quantum computing which is rapidly evolving, has great potential to become a powerful tool to help search for new physics signals. Since the k-means algorithm is known to be able to be accelerated with the help of quantum computing, we investigate and propose an event selection strategy based on k-means algorithm to search for new physics signals. Taking the case of tri-photon processes at the muon colliders as an example, the event selection strategy is shown to be effective in helping to search for the signals of dimension-8 operators contributing to anomalous quartic gauge couplings. Compared with traditional event selection strategy, the expected constraints are generally tighter.
Multicomponent scalar dark matter with an extended Gauge sector
Authors: Coleppa Baradhwaj , Loho Kousik , Sarkar Agnivo 
Published: February 2024

AbstractWe consider an extension of the Standard Model of particle physics with an additional SU(2) gauge sector along with an additional scalar bidoublet and a non-linear sigma field. The neutral components of the bidoublet serve as dark matter candidates by virtue of the bidoublet being odd under a $$Z_2$$

Z
2

symmetry. Generic beyond Standard Model constraints like vacuum stability, invisible decay of Higgs, Higgs alignment limit and collider constraints on heavy gauge bosons restrict the parameter space of this model. In this multicomponent dark matter scenario, we investigate the interplay between the annihilation and co-annihilation channels originating from the new gauge sector as those contribute to the relic abundance. We also inspect the direct detection constraints on scattering cross-sections of the dark matter particles with the detector nucleons and present our observations.
Altered correlation of concurrently recorded EEG-fMRI connectomes in temporal lobe epilepsy
Authors: Wirsich Jonathan , Iannotti Giannina Rita , Ridley Ben , Shamshiri Elhum A. , Sheybani Laurent , Grouiller Frédéric , Bartolomei Fabrice , Seeck Margitta , Lazeyras François , Ranjeva Jean-Philippe , Guye Maxime , Vulliemoz Serge 
Published: February 2024

Abstract
Whole-brain functional connectivity networks (connectomes) have been characterized at different scales in humans using EEG and fMRI. Multimodal epileptic networks have also been investigated, but the relationship between EEG and fMRI defined networks on a whole-brain scale is unclear. A unified multimodal connectome description, mapping healthy and pathological networks would close this knowledge gap. Here, we characterize the spatial correlation between the EEG and fMRI connectomes in right and left temporal lobe epilepsy (rTLE/lTLE). From two centers, we acquired resting-state concurrent EEG-fMRI of 35 healthy controls and 34 TLE patients. EEG-fMRI data was projected into the Desikan brain atlas, and functional connectomes from both modalities were correlated. EEG and fMRI connectomes were moderately correlated. This correlation was increased in rTLE when compared to controls for EEG-delta/theta/alpha/beta. Conversely, multimodal correlation in lTLE was decreased in respect to controls for EEG-beta. While the alteration was global in rTLE, in lTLE it was locally linked to the default mode network. The increased multimodal correlation in rTLE and decreased correlation in lTLE suggests a modality-specific lateralized differential reorganization in TLE, which needs to be considered when comparing results from different modalities. Each modality provides distinct information, highlighting the benefit of multimodal assessment in epilepsy.
Comparing the stability and reproducibility of brain-behavior relationships found using canonical correlation analysis and partial least squares within the ABCD sample
Authors: Nakua Hajer , Yu Ju-Chi , Abdi Hervé , Hawco Colin , Voineskos Aristotle , Hill Sean , Lai Meng-Chuan , Wheeler Anne L. , McIntosh Anthony Randal , Ameis Stephanie H. 
Published: February 2024

Abstract
Canonical correlation analysis (CCA) and partial least squares correlation (PLS) detect linear associations between two data matrices by computing latent variables (LVs) having maximal correlation (CCA) or covariance (PLS). This study compared the similarity and generalizability of CCA- and PLS-derived brain-behavior relationships. Data were accessed from the baseline Adolescent Brain Cognitive Development (ABCD) dataset (N &gt; 9,000, 9–11 years). The brain matrix consisted of cortical thickness estimates from the Desikan-Killiany atlas. Two phenotypic scales were examined separately as the behavioral matrix; the Child Behavioral Checklist (CBCL) subscale scores and NIH Toolbox performance scores. Resampling methods were used to assess significance and generalizability of LVs. LV1 for the CBCL brain relationships was found to be significant, yet not consistently stable or reproducible, across CCA and PLS models (singular value: CCA = .13, PLS = .39, p &lt; .001). LV1 for the NIH brain relationships showed similar relationships between CCA and PLS and was found to be stable and reproducible (singular value: CCA = .21, PLS = .43, p &lt; .001). The current study suggests that stability and reproducibility of brain-behavior relationships identified by CCA and PLS are influenced by the statistical characteristics of the phenotypic measure used when applied to a large population-based pediatric sample.
Similar neural states, but dissimilar decoding patterns for motor control in parietal cortex
Authors: Vaccari Francesco Edoardo , Diomedi Stefano , De Vitis Marina , Filippini Matteo , Fattori Patrizia 
Published: February 2024

Abstract
Discrete neural states are associated with reaching movements across the fronto-parietal network. Here, the Hidden Markov Model (HMM) applied to spiking activity of the somato-motor parietal area PE revealed a sequence of states similar to those of the contiguous visuomotor areas PEc and V6A. Using a coupled clustering and decoding approach, we proved that these neural states carried spatiotemporal information regarding behaviour in all three posterior parietal areas. However, comparing decoding accuracy, PE was less informative than V6A and PEc. In addition, V6A outperformed PEc in target inference, indicating functional differences among the parietal areas. To check the consistency of these differences, we used both a supervised and an unsupervised variant of the HMM, and compared its performance with two more common classifiers, Support Vector Machine and Long-Short Term Memory. The differences in decoding between areas were invariant to the algorithm used, still showing the dissimilarities found with HMM, thus indicating that these dissimilarities are intrinsic in the information encoded by parietal neurons. These results highlight that, when decoding from the parietal cortex, for example, in brain machine interface implementations, attention should be paid in selecting the most suitable source of neural signals, given the great heterogeneity of this cortical sector.
Single nucleotide polymorphism (SNP) marker-assisted breeding of Heterorhabditis bacteriophora for improvement of reproductive potential and stress tolerance
Authors: Ogaya Christopher , Diano Michelle Ann B. , Hategekimana Innocent , Dörfler Verena , Molina Carlos , Ehlers Ralf-Udo 
Published: February 2024

Summary
The entomopathogenic nematode (EPN), Heterorhabditis bacteriophora, is an efficient biological control agent against several economically important insect pests. Recent research has assessed the possibility to correlate desired beneficial traits with genotype data to pave a way for marker-assisted breeding approaches. A collection of H. bacteriophora WT inbred lines has been phenotyped in this framework for stress- and virulence-related traits. However, these traits are rarely combined in a single line. Thus, unifying these traits in commercial strains is of high priority. This investigation unified beneficial traits in hybrid pools through marker-assisted breeding using single nucleotide polymorphisms (SNPs) associated with reproductive potential, longevity, virulence and cold tolerance. Recombinant inbred lines (RILs) generated from a cross between a stress tolerant WT inbred line (XX21) and a line high in in vitro reproduction potential (IL3) were genotyped via SeqSNP and screened for SNP markers associated with beneficial traits. Thereafter, a genotypic pool (X21L3) comprising 22 ILs was formed. The X21L3 pool was subsequently evaluated for the target traits in comparison with the cross parents and a commercial strain HB4. An improvement of oxidative stress tolerance at 2°C (cold tolerance) was recorded with X21L3 surviving 1 day longer than the best performing parent (XX21). The hybrid pool also survived 1 day longer than the least performing parent IL3 for the trait longevity at 25°C under oxidative stress conditions. A higher dauer juvenile (DJ) recovery (58%) and DJ yield (209 000 DJ ml−1) than the least performing parent XX21 was recorded for the pool. The storage stability in diatomaceous earth formulation at 2°C and 7.5°C was also improved by 2 and 5 days, respectively, in comparison to the least performing parent XX21. This study depicts the potential of precision marker-assisted breeding for beneficial trait improvement of H. bacteriophora.
The Adoption of Nabû and Tašmētu into the Babylonian Pantheon
Authors: Rubin Zachary 
Published: February 2024

Abstract
Though Nabû is well known in Babylonian religion as the minister of its patron god Marduk, and Tašmētu as Nabû’s wife, this paper argues that they were not originally envisioned as such. Instead, both the god and goddess seem to have been introduced into Marduk’s circle over the course of the Old Babylonian period, having previously been venerated in independent cults. Unexpected appearances of Tašmētu within the ritual practices of Babylon also suggest that she was only recognized as Nabû’s wife after they were both integrated into the Babylonian pantheon. Evidence of their early independence and subsequent assimilation is drawn from a wide pool of contemporary sources, including god lists, onomastics, and seal inscriptions, as well as descriptions of traditional ritual arrangements from later periods.
In-situ Artefact Documentation of Underwater Cultural Heritage Using Third-Party Data
Authors: Thomsen Mikkel H. , Čvrljak Matko 
Published: February 2024

Abstract
Large underwater construction projects generate hundreds of potential cultural heritage objects requiring archaeological assessment and – potentially – mitigation. Some can easily be avoided in planning, whereas others cannot. Singular objects tend to present a dilemma in heritage management: their archaeological significance tends to lie in their association to an – at the time of finding – unknown context rather than in the object itself. Though these objects may be protected by heritage legislation, they are often undesired in museum collections, and even if destined for disposal, they can only be salvaged and documented at significant cost. Their cultural heritage ‘value’ is often, though mostly tacitly, considered low or at least undecided. We argue that in-situ preservation by record can be a viable solution for such objects, provided that appropriate documentation methods are employed. Fortunately, these objects are often targeted by other types of pre-construction surveys and inspections, usually conducted using remotely operated vehicles (ROVs), making hours of third-party video footage available to the archaeologist. This article examines if existing third-party video inspection data can be used towards acceptable archaeological recording without compromising the cost-efficiency so crucial to the industry. Hence, the focus of this article is the typical industry-standard inspection-, work class-, or even low-end hobby-ROV (from where the jump to legacy data or, indeed, crowdsourcing is obvious), suggesting a few simple amendments to data acquisition specifications which may potentially save the cost of a dedicated archaeological inspection campaign.
A Viking Age Ghost Ship near the Great Halls of Lejre
Authors: Kastholm Ole Thirup 
Published: February 2024

Abstract
Due to persistent rumours of wooden planks from a ‘Viking Ship’ in the Lejre Stream (Lejre Å) running in the Valley of Lejre (Lejre Ådal) and near the dynastic residence of Lejre (the Scyldings’ palace), archaeologists have investigated the area in the 1980s. The negative result has never been the subject of any publication so far, let alone a closer examination of what the background of these rumours might be. This paper aims to present the investigation and its context. Furthermore, it sums up our knowledge about the Lejre Stream, which concludes that it was not a navigable waterway in the Late Iron Age. This investigation also suggests that the so-called ‘ship planks’ represent another wooden structure than a Viking ship, either a ford or a watermill. Finally, it is suggested on the basis of the investigation that the area of the dynastic residence of Lejre would be an ideal place to search for early watermill technology.
Creating Order or Revealing Disorder? Some Preliminary Results Using Multiple Correspondence Analysis (MCA) in Studying Archaeological Boat Finds from Norway (AD 1050–1700)
Authors: Falck Tori , Dubbini Nevio 
Published: February 2024

Abstract
This article discusses the use of statistical methods for systematising 96 archaeological ship finds, mainly from the southern and south-eastern coast of Norway. It draws on an article published in 2009 by Jan Bill, where he did a similar investigation of material from the Danish area. The method of multiple correspondence analysis (MCA) provides a way to summarise categorical data in a reduced number of dimensions. The results are presented in a geographical space, a plot, that can be used for making interpretations and assumptions of cohesions and divergences in the material. It is a way of analysing continuity and change in boatbuilding techniques that avoids using arbitrary and ambiguous concepts of historical (ship) types. Instead, the building techniques, the ways of ‘doing things’, make the premises for classification. The results in this article can be considered preliminary, its primary function being a discussion on methodology.