bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of hepatic steatosis on 18F-FDG uptake in PET-CT examinations of cancer Egyptian patients
Authors: Ali Magdi A. , El-Abd Eman , Morsi Mohamed , El Safwany Mohamed M. , El-Sayed Mohamed Z. 
Published: October 2023

Abstract
Background
Hepatic steatosis is the most common chronic hepatic disease. Imaging diagnosis of hepatic steatosis has been evaluated as an alternative to invasive histological diagnosis.

Study aims
The study aimed to assess the effect of hepatic steatosis on Flourine-18 fluorodeoxyglucose (18F-FDG) uptakes in cancer patients.

Patients and Methods
Blood samples were collected from 50 cancer patients and analyzed to calculate fatty liver index and Hepatic steatosis index (HIS). Hepatic steatosis examined using high-resolution ultrasound and positron emission tomography—computed tomography (PET-CT). Linear attenuation coefficient, standardized-uptake value (SUV) mean (SUV mean), and SUV maximum (SUVmax) were measured. Accordingly, patients were divided equally into non-fatty liver, and fatty liver groups.

Results
A significant increase in SUVmax and SUV mean was observed in the fatty liver group more than in the non-fatty liver group. HSI significantly increased in the fatty liver group compared to the non-fatty liver group. Liver tissue uptake FDG was significantly correlated with HSI values. SUV max significantly correlated with body mass index (BMI) in the non-fatty group only.

Conclusion
Hepatic changes in cancer patients affect the liver metabolic activity and thus the 18 F-FDG uptake. Therefore, further corrections should be considered when the liver is used as a comparator for PET-CT scans of cancer patients.
Obsessions and suicidality in youth suffering from bipolar I disorder
Authors: Ezzat Mohammed , Younis Mohammed Atef , Khalil Mohammed A. , Gomaa Maged E. , Afifi Dina Yosri , Ayoub Doaa R. 
Published: October 2023

Abstract
Background
Obsessive compulsive disorder (OCD) is a common comorbidity with bipolar disorder, a comorbidity that is known to increase suicide risk. This study aimed to assess the presence of OCD in youth diagnosed with bipolar I disorder and to evaluate the association between OCD and suicide in the same cohort.
Eighty subjects diagnosed with bipolar I disorder were enrolled in this study; subjects were divided according to the presence or absence of OCD to group A: bipolar disorder patients with OCD (n = 26) and group B: bipolar disorder patients without OCD (n = 54).
The following scales were applied: Dimensional Yale-Brown Obsessive-Compulsive Scale (DYBOCS)–Beck Scale for Suicidal Ideations (BSSI)–Hamilton Depression Rating Scale (HDRS), and Young Mania Rating Scale (YMRS).

Results
DYBOCS score of group A was 30.23 ± 0.43, and that of group, B was 18.50 ± 1.88 with a significant difference (p < 0.01). There was a significant positive correlation between BSSI and age, age of onset and YMRS in group A (p < 0.01).

Conclusions
The study demonstrated that OCD is a common comorbidity in youth with bipolar I disorder and may be associated with a greater risk of suicide than in youth with bipolar I disorder without comorbid OCD. Furthermore, comorbidity of OCD with bipolar I disorder in youth may be associated with younger age of onset and more severe symptoms profile.
Hepatic mesenchymal hamartoma masquerading as neonatal unconjugated hyperbilirubinemia: a case report
Authors: Mathews Shirbin Joe , Perveen K Athiya , Chandy Bini Mariam , Mathew Ria K. 
Published: October 2023

Abstract
Background
Hepatic mesenchymal hamartoma (HMH) is the second most common benign hepatic tumor in the pediatric age group. The etiology of HMH is unclear. Theories include abnormal hepatic mesenchyme, a reactive change or a proliferative lesion. The condition can present prenatally in USG as a mass, high output cardiac failure, pulmonary hypertension, respiratory distress, and abdominal distension or mass in older children. We present this case to discuss an extremely rare presentation of a comparatively rare disease and to emphasise the need for a high index of suspicion even if the patient presents with symptoms common for that age.

Case presentation
A 7-day-old male baby with an uneventful antenatal period, born by vaginal delivery, with a birth weight of 3.1 kg and normal APGAR scores, presented with jaundice, poor feeding, and labored breathing noticed on the same day itself. Examination revealed a grossly distended abdomen with a mass of size 8 × 7 cm occupying the right side down to the right iliac fossa, crossing midline and dullness continuous with liver dullness. On investigation an abnormal liver function test with unconjugated hyperbilirubinemia was seen. USG and CECT abdomen were suggestive of HMH with close proximity to hepatic vessels. Exploratory laparotomy and near total excision with marsupialisation was done. Histopathology report was suggestive of HMH. A 2-year follow-up was normal.

Conclusion
This case of HMH presented as neonatal jaundice with unconjugated hyperbilirubinemia which is a rarity. We had to limit our surgery to near total excision and marsupialisation due to its proximity to vascular structures.
Chylolymphatic cyst as a rare cause of acute intestinal obstruction in infants
Authors: Ali Ahmed K. , Abdelhamid Islam M. , Mohamed Abdelrahman Hamdy , Sabra Tarek Abdelazeem 
Published: October 2023

Abstract
Background
Chylolymphatic cysts are benign pathology in lymphatic vessels due to obstruction in the lymphatic system. Their incidence is still unknown. However, they account for approximately 3 to 9% of all pediatric lymphangiomas. Most of these lesions are asymptomatic and are discovered accidentally. They can be presented with nonspecific abdominal pain, vomiting, and changes in bowel habits. Rarely, chylolymphatic cysts can as intestinal obstruction, volvulus or even torsion.

Case presentation
A 3-month-old male presented to our unit with manifestations of acute intestinal obstruction. Abdominal examination revealed signs of generalized peritonitis and intestinal obstruction. Abdominal ultrasound revealed minimal turbid intraperitoneal collections and no motility of bowel loops. Plain erect abdominal radiograph revealed multiple small bowel air fluid levels. Abdominal exploration revealed a large chylolymphatic cyst causing acute intestinal obstruction. Excision of the cysts was done with preservation of adjacent bowel loop. The patient was discharged in good health on the 6th day postoperative. A chylolymphatic cyst with a diameter of 5 cm was identified by histological investigation.

Conclusions
Most chylolymphatic cysts in infants are asymptomatic, but they can cause fatal complications such as intestinal obstruction, volvulus, or even torsion.
The LEAP checklist for laboratory evaluation and analytical performance characteristics reporting of clinical measurement procedures
Authors: Loh Tze Ping , Cooke Brian R. , Tran Thi Chi Mai , Markus Corey , Zakaria Rosita , Ho Chung Shun , Theodorsson Elvar , Greaves Ronda F. 
Published: October 2023

Abstract
Reporting a measurement procedure and its analytical performance following method evaluation in a peer-reviewed journal is an important means for clinical laboratory practitioners to share their findings. It also represents an important source of evidence base to help others make informed decisions about their practice. At present, there are significant variations in the information reported in laboratory medicine journal publications describing the analytical performance of measurement procedures. These variations also challenge authors, readers, reviewers, and editors in deciding the quality of a submitted manuscript. The International Federation of Clinical Chemistry and Laboratory Medicine Working Group on Method Evaluation Protocols (IFCC WG-MEP) developed a checklist and recommends its adoption to enable a consistent approach to reporting method evaluation and analytical performance characteristics of measurement procedures in laboratory medicine journals. It is envisioned that the LEAP checklist will improve the standardisation of journal publications describing method evaluation and analytical performance characteristics, improving the quality of the evidence base that is relied upon by practitioners.
The European Union and Achieving Peace in Ukraine
Authors: Corneo Giacomo 
Published: October 2023

Abstract
The war between Ukraine and Russia does not only harm their respective populations: the rest of Europe is heavily affected. While some welfare losses for the EU are salient, the most significant one is not: it is the risk that the war escalates into a major nuclear conflict. A promising policy to minimize those losses exploits the desire of both Ukrainians and Russians to join the EU. I propose that they should if they immediately cease all fighting and subscribe to a distinctive, incentive-compatible, peace agreement brokered by the EU. Such an agreement would come at small costs to the EU, costs that would vanish in comparison to the risk of nuclear holocaust.
Resources mobilisation challenges in rural schools of South Africa: What can we learn?
Authors: Mkhize Themba  Ralph , Davids Mogamat Noor 
Published: October 2023

Government efforts to provide equal and quality education in rural schools has yielded minimal change in South Africa since the dawn of democracy in 1994.Growing inequalities and recent economic constraints exacerbated by the COVID 19 pandemic have further exposed and deepened resource scarcity among rural communities and schools. The South African Schools Act (1996) is clear that, through school stakeholders such as School Governing Bodies (SGB’s), schools are required to supplement resources provided by the State. However, there is a paucity of research that explores resource mobilisation challenges experienced by school stakeholders in rural schools of South Africa. The article is based on a qualitative research study, supported by the Asset-based theory and Resource mobilisation theory. To collect data, we used participatory approaches such as the Free Attitude Interviews (FAI) and SWOT analysis. Four main findings emerged from the data, which were used to make recommendations to address and improve the quality of education in rural communities.
Workplace Risk Factors Assessment in North-Azadegan Oil Field Based on Harmful Agents Risk Priority Index (HARPI)
Authors: Askari Ali , Poursadeghiyan Mohsen , Alinia Alimardan , Sephvand Arash , Jafarzadeh Emad , Nasl-Saraji Gebraeil , Sahlabadi Ali Salehi 
Published: October 2023

Background: Considering the necessity of health risk management, the present study conducted to provide a comprehensive model for identifying, evaluating, and prioritizing occupational health risks in an oilfield.
Methods: We conducted this descriptive-analytical cross-sectional study in 2022 at the North-Azadegan oil field in Iran. The occupational health risk was assessed using the "Harmful Agents Risk Priority Index" (HARPI) method.
Results: Among the employees for the office section in all job groups, ergonomic risks due to people's posture while working has the highest risk score and is the most critical risk for implementing corrective actions. In the operational section, for the HSE group, benzene, the production group, Electromagnetic Fields (EMFs), and other groups, undesirable lighting has the highest risk score, and exposure to Toluene, Ethylbenzene, Xylenes (TEX) has the lowest risk score. In this oil field, controlling exposure to benzene, correcting ergonomic conditions, and controlling noise exposure, with scores of 81.3,74.85 and 71.36, have the highest priority, respectively. Sequentially, Toluene, Xylene, and ethylbenzene, with scores of 10.25,11.61, and 11.61, have the lowest control priority.
Conclusion: The proposed model can prioritize the workplaces' harmful agents based on the HARPI score due to exposure to chemicals, physical factors, and analysis posture.
The Prevalence of Hypertension and Obesity in Iranian Professional Drivers
Authors: Nikpajouh Akbar , Noohi Feridoun , Malakpour Mokhtar , Tajik Majid , Mahmoudzadeh Amir , Moghadam Peyman , Salesi Mahmood , Raei Mehdi , Shahrbaf Mohammad Amin 
Published: October 2023

Background: Professional driving is associated with overworking, lack of physical activity, and high stress, which are susceptible to cardiovascular diseases (CVDs). We aimed to determine the prevalence of hypertension and obesity in Iranian professional drivers.
Methods: Overall, 132,452 drivers were included by census sampling methods and those who did not pass periodic examinations were excluded. Demographics and anthropometric data, including height and weight and the driver's blood pressure, were recorded. The criteria for hypertension assumed as the systolic blood pressure ≥ 130 mm and/or diastolic blood pressure ≥ 80 mm, and the criteria for prehypertension assumed as 120–129 systolic and < 80 mm Hg. In addition, body mass index (BMI) ≥ 25 is assumed as overweight, and BMI ≥ 30 is assumed as obesity.
Results: Overall, 113,856 male drivers were included in the final analysis. The prevalence of HTN, pre-HTN, and abnormal blood pressure (HTN + pre-HTN) was calculated to be 14.2%, 57.4%, and 71.6%, respectively. Khuzestan, West Azerbaijan, and Yazd had the most prevalence of abnormal blood pressure. The prevalence of overweight, obesity, and abnormal weight (overweight + obesity) was calculated to be 50.9%, 22.6%, and 73.5%, respectively, and the northwest provinces had the highest prevalence of abnormal weight.
Conclusion: Professional Iranian drivers have a high prevalence of abnormal blood pressure and weight associated with job-related risk factors. Preventive measures should be taken to confront a possible outbreak of CVDs in this population.
Economic Burden of Vision Loss and Eye Disorders in Iran
Authors: Rezapour Aziz , Adel Amin , Aboutorabi Ali , Askarzade Elahe , Barghazan Saeed Husseini , Pourtaleb Arefeh , Tabatabaee Seyed Saeed 
Published: October 2023

Background: Globally, population growth and ageing are expected to increase the risk of vision impairment for more people. Eye disorders impose heavy social and economic burdens on communities through increased poverty, reduced quality of life, and decreased employment. Weaimed to calculate the economic burden of eye diseases in Iran.
Methods: Prevalence-based and top-down cost estimation methods were used with a sociological approach. Data were collected from the Northeastern Ophthalmology Center Institute for Health Assessment, and Evaluation, besides the 2017 census. Eye diseases were classified according to the ICD10. Data were analyzed using Excel 2016 software.
Results: Survey data were collected from 19,113 patients with vision loss and eye disorders. The average cost of vision loss/eye disorders was estimated to be $250.3. The findings indicated that the economic burden of visual diseases was $2,844 million a year, with direct medical costs comprising 87% (66% of inpatient and 21% of outpatient) and direct non-medical and indirect costs estimated at 6% and 7%, respectively. Furthermore, 72.8% of direct medical costs was paid by insurance companies, 20.6% by patients, and 6.6% by the government.
Conclusion: Eye diseases and vision loss in Iran, as in other countries, are costly for the health system and society. Instituting effective policies and measures to address this rising burden should be a national priority. Another suggestion in this area would be to focus on preventive care and policies such as health education, highlighting the role of reorientation of health services and advocacy (for policies that promote eye health), where relevant.
Emergency Department Neurosurgical Consultations in a Tertiary Care Hospital
Authors: ŞENGÜLDÜR Erdinç , SELKİ Kudret , TUNCER Cengiz , DEMİR Mehmet Cihat 
Published: October 2023

Objective: To reveal the characteristics of patients needing neurosurgery by examining neurosurgery consultations within the emergency department (ED) admissions of a tertiary academic hospital.
Method: This is a retrospective, single-centre observational study. Patients admitted to the ED between 01.01.2022 and 31.12.2022 and consulted to the neurosurgery department were identified through the hospital computer system and included in the study. The demographic information of the patients, mode of admission to the ED, the reasons for admission, the time of admission, the number of brain computed tomography (CT) scans, whether they underwent surgery or not, and the mortality results were recorded.
Results: A total of 441 neurosurgery consultations were examined. Fall 35.6% (n=157) and traffic accident 16.6% (n=73) were the most common reasons for consultation. It was observed that 92.5% (n=408) of the patients had a brain CT scan, and 19.5% (n=86) had two or more brain CTs. It was determined that 12.7% (n=56) of the patients consulted for neurosurgery were operated on, and 4.1% (n=18) of the patients' hospital admissions resulted in death. Only 53.7% (n=237) of the patients who underwent neurosurgery consultation were discharged from the ED. It was determined that significantly more Neurosurgery consultations were requested during working hours (p = 0.013)
Conclusion: Most consultation calls from the ED to neurosurgery are for trauma patients. Brain CT examination is frequently used in neurosurgical patient evaluation. As a result of the consultations, almost half of the patients are hospitalized. Emergency physicians can select patients who need neurosurgery well.
KLASİK TÜRK ŞİİRİNDE SEVGİLİNİN GÜZELLİK UNSURLARININ KANLA İLİŞKİLENDİRİLMESİ
Authors: NAYİR EKİNCİ Hilal , BİLEN Sümeyye 
Published: October 2023

Damarların içinde dolaşan kırmızı renkli sıvı, insan için hayati önem taşımaktadır, bu nedenle insanlar, zaman içerisinde hayatın pek çok farklı alanında kana çeşitli anlamlar yüklemişlerdir. Kanın sağaltıcı, koruyucu ve arındırıcı özellikleri vardır. Bu özelliklerine binaen güç ve canlılık verici, kötülüklerden arındırıcı olduğuna inanılmıştır. Kana verilen önem ve birtakım inançlar ışığında ortaya çıkan anlamlar, klasik Türk şiirinde de yer edinmiştir. Dinî inançlar ve halk kültüründe kana atfedilen anlamlar, kan ile ilgili deyimler ve tabirler klasik Türk şairlerinin şiirlerinde karşımıza çıkar. Klasik Türk şiirinde sevgilinin kanla ilgisi “hûn, dem, kan” kelimeleri ile farklı teşbih ve mecazlarla ifade edilir. Kan ve sevgili çeşitli unsurlar vasıtasıyla birbiriyle ilişkilendirilir.
Metin merkezli bu çalışmada 15 ve 16. yüzyıl klasik Türk şiirinden seçilen örnek beyitlerde sevgilinin güzellik unsurları ile kan arasındaki ilişki inançlarda, halk kültüründe, dönemin gelenek ve görenek anlayışında kanın güzellik unsurlarına yansıyan kısımlarında araştırılmıştır. Çalışmada, klasik Türk şiirinde sevgilinin güzellik unsurları çerçevesinde kan ve kanla aynı anlama gelen kelimeler, teşbih, mecazlar, söz sanatları açısından incelenmiş, şairlerin hayal dünyasında yer edinmiş kanla bağlantılı diğer unsurlarla birlikte değerlendirilmiştir.
THE EFFECT OF MEDIA USE ON THE INTERGENERATIONAL PERCEPTION OF HEALTH RISKS DURING THE COVID-19 PANDEMIC: QUANTITATIVE SHORT REPORT OF MALTEPE UNIVERSITY SCIENTIFIC RESEARCH PROJECT
Authors: AKŞİT Gökçesu , YAZICIOĞLU İlknur 
Published: October 2023

ABSTRACT
Objective: This research was carried out in order to show the effect of the use of media tools on the risk perception of the society in the context of generations during the Covid-19 pandemic.
Methods: The research was conducted with mixed method in which quantitative and qualitative research techniques were used together. The “Converging Parallel Mixed Method” was used and the findings obtained from the both methods were combined. Media Exposure Scale, Risk Perception Scale, The Behavior Scale and The Believability Scale were used for the quantitative part. In-depth interviews were conducted for the qualitative part.
Results: In the quantitative part of this study, it was found that the most important behavioral difference is that the use of media directly affects vaccination behavior in all generations. It has been also determined that the media use variable doesn’t differ according to age groups, thus all generational groups were found to use media invariably from each other.
Conclusion: It is of great significance that the information that both the whole society and individuals over the age of 65, who are in the risk group in terms of Covid-19 contamination and adverse process, need or may need, should be given in the most perspicuous, accurate and current manner in the media.

Keywords: Covid-19, Explanatory Model, Health Communication, Risk Perception, Stigma.
Maximizing the Moran effect: summer solstice orchestrates the subcontinental-scale synchrony of mast seeding
Authors: Bogdziewicz Michal , Szymkowiak Jakub , Foest Jessie , Hacket-Pain Andrew , Kelly Dave , Journé Valentin 
Published: October 2023

Abstract
High interannual variation in seed production in perennial plants can be synchronized at subcontinental scales with wide consequences for ecosystem functioning, but how such synchrony is generated is unclear. We investigated the factors contributing to masting synchrony in European beech, spanning an impressive 2000 km geographic range. Maximizing masting synchrony via spatial weather coordination, known as the Moran effect, requires distant populations to react simultaneously to weather conditions. A celestial cue that occurs simultaneously across the entire Hemisphere is the longest day (summer solstice). We show that European beech abruptly opens its temperature-sensing window on the solstice, hence widely separated populations all start responding to weather signals in the same week. This celestial "starting gun" generates ecological events with unparalleled spatial synchrony across the continent.
Clay-Polymer Nanocomposites Mediated Inhibition of Protein
Aggregation: Possible Role in the Prevention of Proteinopathies
Authors: Parveen Romana , Ali Sher , Fatima Sadaf 
Published: October 2023

Background:
The transformation of proteins from their native conformation into highly
ordered fibrillar structures due to their misfolding and aggregation under particular conditions are
described as beta-sheet enriched amyloid fibrils. The accumulation of these fibrils in different
body parts is the major cause of several neurological and non-neurological conditions (proteinopathies).

Objectives:
To prevent these proteinopathies, inhibition of protein aggregation is considered a
promising strategy. Therefore, in this study, we synthesized montmorillonite (MMT) based poly-
orthophenylenediamine (PoPD) nanocomposites (NCs) and characterized their size and morphology
due to their remarkable biological properties. Further, the effect of these nanocomposites
on inhibition of fibril formation was assessed.

Methods:
These nanocomposites were evaluated for their anti-amyloidogenic potential on two
model proteins of amyloidopathies, i.e., human lysozyme and human serum albumin (HL &
HSA), by using several biophysical methods, such as Thioflavin T (ThT) and 1-anilino-8-naphthalene
sulfonate (ANS) fluorescence, congo red dye binding assay (CR). Secondary structural content
was evaluated by Circular dichroism (CD) spectroscopy.

Results:
Results demonstrated that synthesized nanocomposites significantly inhibited fibril formation
in dose-dependent manner that corresponds to their ability to arrest fibrillation. It is suggested
that they may adsorb proteins to protect them against aggregation when they are subjected to aggregating
conditions.

Conclusion:
This study offers an opportunity to understand the mechanism of inhibition of fibril
formation by nanocomposites, showing that they inhibit amyloid formation and amyloid diseases.
Thus, the study concludes that these nanocomposites are promising candidates as therapeutic
molecules for proteinopathies and are envisaged to enrich the area of personalized medicine, augmenting
the human healthcare system.