bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determining the Effect of Voluntary Participation in Communicating with PLHIV in Siaya County, Kenya
Authors: Marimba Benson Kairichi , Mberia Hellen , Kimalu Paul 
Published: January 2024

Purpose: This research aimed to determine 1the effect 1of voluntary participation 1in communicating with PLHIV 1in 1Siaya, 1Kenya.
Methodology: This study utilized a 1descriptive research approach and 1inferential 1design through a 1field survey, employing two distinct 1sets of questionnaires. One was administered 1to the key informant and the other to Persons Living with HIV (PLHIV).1Spearman’s 1rho 1correlations 1and simple linear1regression1models were also applied to assess the association between voluntary engagement as 1the independent variable and communication as the 1dependent 1variable. ANOVA 1test 1was also performed 1to test the hypothesis 1and results were 1presented 1in 1tables.
Findings: The study comprised a sample size of 376 individuals, constituting 96.18% of willing respondents who agreed to participate in 1interviews. Seventeen unresponsive records were excluded from the analysis. A Normality 1Test was conducted to assess whether the study sample was drawn from a population with a normal distribution. Under the 1null 1hypothesis, no significant difference was found between the sample and the population it represented. Consequently, there was substantial evidence to reject the 1null 1hypothesis and accept the 1alternative 1hypothesis (p-value=0.000 CI=95%). Moreover, the findings revealed that 82.30% voluntarily enrolled in the 1Text 1for 1Adherence (T4A) 1mobile 1app, 70.71% signed the consent form, and 6.07% indicated that 1consent was implied.
Unique Contribution to Theory, Practice and Policy: This study extends 1Technology readiness theory studies to mhealth field where it is beginning to gain traction. It also indicates the significance of individuals willingly participating in mHealth interventions upon enrollment. Voluntary participation is an imperative condition of any research undertaking. This study's results additionally confirmed that mHealth interventions enhance the well-being of individuals managing chronic illnesses. This study is likely to inform policy changes and or amendments in the mhealth space in many jurisdictions. An 1intervention 1such 1as 1Text for1Adherence (1T4A) may encourage 1the 1government 1to support system developers. It can also take over the project as a public health investment instead of leaving it to private sector or non-governmental organizations. Study further extends the body of knowledge in use of mhealth interventions.
Innovation Practices: Catalyst for SMEs Performance in Anambra State, Nigeria
Authors: Okoli Nuel , Nuel-Okoli Maureen , Ibekwere M. 
Published: January 2024

Purpose: The shortfall of innovation practices among SMEs in Anambra State necessitated this study. The study aimed to investigate the influence of innovation practices on the performance of Small and Medium Scale Enterprises in the selected SMEs from different sectors in Anambra State.
Methodology: Cross-sectional research design was adopted by the study. The population of the study consisted of 15 selected SMEs from different sectors totaling one thousand eight hundred and sixty (1860) management and workers of the selected SMEs in Anambra State. A sample size of 300 was determined using Krejcie and Morgan (1970) formula. For the purpose of this study, the primary source of data (questionnaire), which was subjected to both validity and reliability was utilized. Both descriptive and inferential statistics were adopted in data analysis and the hypotheses were tested at a 5% level of significance.
Findings: The study revealed from the analysis that product innovation has a statistically positive relationship with customer satisfaction (r = .847; P-value < 0.05) and between process innovation and customer retention (r = .813; P-value < 0.05). Also revealed was technological innovation has a statistically significant influence on competitive advantage (r = .769; P-value < 0.05) and that marketing innovation has a statistically significant influence on brand awareness (r = .790; P-value < 0.05). It was concluded that innovation practices have a significant relationship with performance of SMEs.
Unique Contribution to Theory, Practice and Policy: The study advocated that creative and quality on product innovations need to be maintained continuously to develop appropriate product continually and increase the customer satisfaction. SMEs need to be passionate about incorporating technological innovation qualities that will assist employee performance to delivers satisfaction to their customers through technological innovation that will keep attracting new customers and retaining customers through employee performance. Also, more investment need to be made in research and development to be able to innovate more and adopt more innovative strategies to improve their market innovation.
High iNOS and IL-1β immunoreactivity are features of colitis-associated colorectal cancer tumors, but fail to predict 5-year survival
Authors: Björner Kajsa , Chen Wei-Na , Gannavarapu Venkata Ram , Axling Fredrik , Gulyas Miklos , Halim Mohammad Abdul , Webb Dominic-Luc , Hellström Per M. 
Published: January 2024

Background: Inflammatory bowel disease (IBD; mainly ulcerative colitis and Crohn’s disease) is associated with the development of colorectal cancer (CRC) referred to as colitis-associated colorectal cancer (CAC). In inflammatory flares of IBD, the production of luminal nitric oxide (NO) increases due to the increased inducible nitric oxide synthase (iNOS) activity in inflamed tissue. It is believed that iNOS parallels pro-inflammatory interleukin-1β (IL-1β). How these biomarkers relate to CAC pathogenesis or survival is unknown.
Aim: The primary aim of this study was to investigate iNOS and IL-1β immunoreactivity in CAC tumors in comparison with CRC and normal colonic mucosa, and the secondary aim was to determine if immunoreactivity correlates with 5-year survival of CAC.
Methods: Immunohistochemistry was performed on tissue sections as follows: CAC (n = 59); sporadic CRC (sCRC) (n = 12); colonic mucosa >2 cm outside sCRC margin (normal mucosa) (n = 22); paracancerous IBD (pIBD) (n = 12). The expression of iNOS and IL-1β was quantified separately for epithelium and stroma. Data were evaluated using the Mann-Whitney U-test and the log-rank test for 5-year Kaplan-Meier survival curves. Results were compared with online mRNA databases.
Results: Immunoreactivity occurred predominantly in epithelial cells and to lesser extent in stroma. Compared with normal mucosa, immunoreactivity for iNOS (P < 0.01) and IL-1β (P < 0.005) was higher in CAC epithelium. In CAC stroma, iNOS immunoreactivity was lower than normal mucosa (P < 0.001), whereas IL-1β was higher (P < 0.05). Immunoreactivity differences of iNOS or IL-1β among CAC patients failed to correlate with 5-year survival. These findings were supported by online mRNA databases.
Conclusion: Consistent with high NO production in IBD, there is more iNOS in CAC epithelium, albeit not in stroma. This immunoreactivity difference exists for IL-1β in both epithelium and stroma. The intervention of arginine or iNOS activity for CAC chemotherapy is not straightforward.
¿Nuevas cartografías del tiempo?: historicidad, conflictos y apertura de posibilidades
Authors: Medel Barragán Daniel 
Published: January 2024

A partir de una lectura cruzada entre el reciente libro de Berber Bevernage, Historia, memoria y violencia estatal. Tiempo y justicia, y algunas premisas surgidas del reciente “giro temporal” en la reflexión teórica de la historia se plantean vías o contextos de lectura para contextualizar las premisas sobre las temporalidades espectrales.
El primero de estos contextos consiste en la idea de que los movimientos sociales esgrimen diversas temporalidades en los espacios públicos para configurar distribuciones nuevas de las memorias y las duraciones o persistencias de pasados difíciles. En este sentido, se observa que las temporalidades siempre se configuran desde espacios agónicos o de constante disenso asediados por los espectros de pasados difíciles.
El segundo contexto de lectura es inscribir las premisas de Bevernage sobre los tiempos espectrales en cuatro sensibilidades que territorializan las actuales postulaciones de las temporalidades: a) el conflicto y la apertura de posibilidades; b) las heterocronías y espectrologías; c) las temporalidades post-naturales; d) temporalidades queer. Desde estas claves de lectura se comenta el planteamiento espectral y derrideano de Bevenarge, la crítica al tiempo modernista y los binarismos entre ausencia/distancia y presencia/ausencia. En paralelo, se plantean algunas interrogantes necesarias para las operaciones historiográficas contemporáneas que pasan por la dimensión ética del tiempo y los fantasmas de los pasados violentos, coloniales, racistas y de la precariedad.
Didjazá: el papel de agencia de Juana Catarina en la construcción del Estado-Nación mexicano
Authors: Canseco Acosta Álvaro Miguel 
Published: January 2024

El presente libro analiza el papel de agencia de las mujeres en la emergencia, consolidación y decadencia del proyecto nacional modernizador en el istmo de Tehuantepec. Al mismo tiempo, realiza un desmontaje de la imagen que se tiene de las mujeres como sujetos con agencia política en nuestro país.
CÁC TÁC DỤNG KHÔNG MONG MUỐN CỦA BỆNH NHÂN UNG THƯ TUYẾN TIỀN LIỆT KHÁNG CẮT TINH HOÀN ĐƯỢC HÓA TRỊ THEO PHÁC ĐỒ DOCETAXEL – PREDNISOLONE
Authors: Đỗ Anh Tú , Dương Thị Lệ 
Published: January 2024

Tác dụng không mong muốn của phác đồ docetaxel phối hợp prednisone chủ yếu được báo cáo là giảm bạch cầu (10%), nôn (32%), tiêu chảy (12%). Ccác độc tính thuốc có thể dung nạp được. Mục tiêu: Đánh giá các tác dụng không mong muốn của bệnh nhân ung thư tuyến tiền liệt kháng cắt tinh hoàn được điều trị bằng phác đồ Docetaxel-Prednisolone. Đối tượng và phương pháp nghiên cứu: Nghiên cứu phân tích cắt ngang tác dụng không mông muốn của việc điều trị hóa chất ở 31 bệnh nhân CRPC. Kết quả nghiên cứu: Trên hệ tạo huyết, độc tính thường gặp nhất là thiếu máu (61,3% bệnh nhân) và giảm bạch cầu (38,7%), tuy nhiên, chủ yếu độc tính gặp ở mức độ 1-2, tỉ lệ hạ bạch cầu độ 3-4 chiếm 3,2% và có thể kiểm soát được. Độc tính trên gan (29%) và thận (22.6%) gặp ở mức độ nhẹ. Kết luận: Hóa trị bằng docetaxel –prednisolone là phác đồ an toàn và có hiệu quả trong điều trị ung thư tuyến tiền liệt kháng cắt tinh hoàn
توجهات ادارة المعرفة لدى مدرسي المرحلة الاعدادية
Authors: الباحثة :غدير على الله شاكر أ.م.د راضي حسن عبيد الجبوري 
Published: January 2024

This research aims to : The current research aims to identify the level of knowledge management of middle school teachers as well as the statistically significant differences for the variable of knowledge management orientations according to the gender variable (male, female) and specialization (scientific, human). To achieve the research objectives, the researcher proceeded to: 1-	Using the descriptive associative approach to reveal the importance of e-learning and knowledge management 2-	-Adopting the knowledge management scale prepared by (Al-Abdullah, Al-Gharawi, 2020). The scale may consist of four areas (knowledge generation, knowledge storage, knowledge distribution, knowledge application). The scale included (40) items distributed over four journals. To complement that, the researcher applied the two scales to a sample of (400) teachers and schools in middle schools (boys and girls schools) affiliated to the Center of the General Directorate of Al-Qadisiyah Education, which were selected by the stratified random method according to the proportional method. Search for the following results: 1-Teachers in the preparatory stage have a knowledge management orientation. 2-There are statistically significant differences in knowledge management orientations among middle school teachers according to gender (males, females) in what there are no statistically significant differences in knowledge management orientations according to specialization (scientific, human), as well as the presence of statistically significant differences in knowledge management orientations. To the interaction of sex with the specialty According to the results of the current research, the researcher came up with a number of recommendations and suggestions, including: 1-Reconsidering educational policies related to the mechanisms of applying knowledge management 2-Building a clear strategic plan for the application of knowledge and the mechanisms for acquiring it 3-Holding training courses for middle school teachers on how to apply knowledge management and benefit from it. 4-Conducting studies to reveal the readiness of students to learn through the technologies of the e-learning system
Soil priming effects and involved microbial community along salt gradients
Authors: Zhang Haoli , Chang Doudou , Zhu Zhifeng , Meng Chunmei , Wang Kaiyong 
Published: January 2024

Abstract. Soil salinity mediates microorganisms and soil processes, like soil organic carbon (SOC) cycling. Yet, how soil salinity affects SOC mineralization via shaping bacterial community diversity and composition remains elusive. Therefore, soils were sampled along a salt gradient (salinity at 0.25 %, 0.58 %, 0.75 %, 1.00 %, and 2.64 %) and incubated for 90 d to investigate (i) SOC mineralization (i.e., soil priming effects induced by cottonseed meal, as substrate) and (ii) the responsible bacteria community by using high-throughput sequencing and natural abundance of 13C isotopes (to partition cottonseed-meal-derived CO2 and soil-derived CO2). We observed a negative priming effect during the first 28 d of incubation that turned to a positive priming effect after day 56. Negative priming at the early stage might be due to the preferential utilization of cottonseed meal. The followed positive priming decreased with the increase in salinity, which might be caused by the decreased α diversity of microbial communities in soil with high salinity. Specifically, soil pH and electrical conductivity (EC) along the salinity gradient were the dominant variables modulating the structure of the microbial community and consequently SOC priming (estimated by distance-based multivariate analysis and path analysis). By adopting two-way orthogonal projections to latent structures (O2PLS), priming effects were linked with specific microbial taxa; e.g., Proteobacteria (Luteimonas, Hoeflea, and Stenotrophomonas) were the core microbial genera that were attributed to the substrate-induced priming effects. Here, we highlight that the increase in salinity reduced the diversity of the microbial community and shifted dominant microorganisms (Actinobacteria and Proteobacteria: Luteimonas, Hoeflea, and Stenotrophomonas) that determined SOC priming effects, which provides a theoretical basis for understanding SOC dynamics and microbial drivers under the salinity gradient.
Impelentasi Manajemen Konflik di Sekolah
Authors: Agung Agung Fahruzi , Hidayat Wahyu 
Published: January 2024

Manajemen konflik dapat diartikan sebagai cara penyusunan atau strategi dalam mengatasi sebuah konflik yang sedang terjadi dan mengendalikannya untuk menghasilkan sebuah harapan yang diinginkan bersama dalam organisasi. Penelitian ini menggunakan pendekatan kualitatif dengan metode deskriptif. Data dikumpulkan dengan wawancara, observasi, dan studi dokumentasi. Adapun analisis dilakukan dengan teknik deskriptif. Implementasi manajemen konflik yang dilakukan oleh kepala sekolah di SMP IT Al Mustaqimiyyah sudah berjalan cukup baik. Hanya saja kepala sekolah kurang dalam berkomunikasi, baik dengan bawahannya maupun dengan para siswanya. Maka untuk mengoptimalkan manajemen konflik di sekolah ialah dengan berusaha membangun komunikasi dengan baik dan mempelajari hal-hal yang berkaitan dengan sifat setiap individu, karena sifat setiap individu tentunya berbeda-beda di sekolah.
Kamu Sağlık Personelinin Kusuru Nedeniyle İdarece Ödenen Tazminatın Rücu Edilmesi
Authors: YILDIZ AKGÜL Şerife 
Published: January 2024

Sağlık Hizmetleri Temel Kanunu’nda yapılan değişiklik ile kamu kurum ve kuruluşları ile devlet üniversitelerinde görev yapan sağlık meslek mensupları için yeni bir sistem geliştirilmiştir. Bu kapsamda uzman bir kurul; Mesleki Sorumluluk Kurulu oluşturularak görev suçları bakımından soruşturma izni vermek ve aynı zamanda rücu konusunda karar vermekle yetkilendirilmiştir. Yeni düzenleme, özellikle rücu mekanizmasının işletilme koşulları bakımından önem arz etmektedir. Bu çalışmada rücu kurumu, öncelikle yeni düzenlemenin kişi ve konu bakımından kapsamı ve kapsam konusunda düzenlemedeki eksiklik ve belirsizlikler ele alınarak tartışılmıştır. Çok farklı işlem, aşama ve adli yargının hem ceza yargılaması hem rücu davası yoluyla, idari yargının tam yargı davası ve sonrasında Mesleki Sorumluluk Kurulu kararına karşı açılacak iptal davası ile dahil olduğu süreçte, rücu mekanizmasının anayasal ilke
ve kurallarda öngörüldüğü şekliyle ne derece işletilebileceği sorusu ele alınarak bazı sorunlar bakımından çözüm önerilerine yer verilmiştir.
TRAVMAYA BAĞLI ALT EKSTREMİTE FRAKTÜR CERRAHİSİ HASTALARINDA OREM’İN ÖZ BAKIM TEORİSİNE TEMELLENDİRİLMİŞ TELE-HEMŞİRELİK UYGULAMASININ ÖZ BAKIM GÜCÜ VE GÜNLÜK YAŞAM AKTİVİTELERİNE ETKİSİ: RANDOMİZE KONTROLLÜ DENEYSEL ÇALIŞMA PROTOKOLÜ
Authors: AKARSU Kamile , GÜLER Sevil , TURKTAS Ugur 
Published: January 2024

Giriş: Travmatik yaralanmalar genellikle düşme, taşıt kazası ve şiddet kaynaklı gerçekleşerek mortalite, morbidite ve engelliliğe neden olmaktadır. Tele-hemşirelik izlemi ile hastaların taburculuk sonrası yaşadıkları sorunlarda yalnız kalmaları önlenirken, hemşirelik teorilerinin ve modellerinin kullanılması ile bu izlemlerde sağlığın korunması ve geliştirilmesinin yanı sıra, hemşirelere yol gösterici rol oynaması da sağlanabilmektedir. Bu çalışmada, travmaya bağlı alt ekstremite fraktür cerrahisi hastalarında Orem’in Öz Bakım Teorisine temellendirilmiş tele-hemşirelik uygulamasının öz bakım gücü ve günlük yaşam aktivitelerine etkisini belirlemek amaçlanmaktadır.
Yöntem: Araştırmanın, Eylül 2022-Ocak 2024 tarihleri arasında yapılması planlanmaktadır. Araştırma, Türkiye’nin bir ilindeki kamu üniversitesi hastanesi ve şehir hastanesine bağlı Ortopedi ve Travmatoloji Kliniklerinde, randomize kontrollü deneysel araştırma tasarımı ile prospektif olarak gerçekleştirilecektir. Araştırmanın örneklemine, 26’sı müdahale, 26’sı kontrol üzere 52 hasta alınacaktır. Verilerin toplanmasında Özbakım Gücü Ölçeği, KATZ günlük yaşam aktiviteleri ölçeği (KGYAÖ), Lawton Brody Günlük Yaşam Aktiviteleri Ölçeği (LBGYAÖ) ve araştırmacılar tarafından literatür ışığında oluşturulacak tanıtıcı bilgi formu kullanılacaktır.
Bulgular: Bu çalışma, randomize kontrollü deneysel çalışmanın protokolünü içermektedir. Çalışma verileri toplanıp analiz edildikten sonra bulgular açıklanacaktır.
Sonuç: Travmaya bağlı alt ekstremite ameliyatı yapılan hastalarda taburculuk sonrası Orem’in Öz Bakım Teorisine temellendirilmiş tele-hemşirelik uygulamasının öz bakım ve günlük yaşam aktiviteleri üzerine etkinliği değerlendirilecektir.
Oosit Maturasyonu Sürecinde Global DNA Metilasyonunun Değişimi
Authors: ŞÜKÜR Gözde , BOZDEMİR Nazlıcan , ÇINAR Özgür 
Published: January 2024

Amaç:
Bu çalışmada, global DNA metilasyonunun Germinal Vezikül (GV) aşamasından Metafaz II (MII) aşamasına kadar olan oosit maturasyonu sürecinde değişim gösterip göstermediğinin ortaya konulması amaçlanmıştır.
Yöntem:
Bu çalışmada, 4 haftalık Balb/C farelerinin GV ve in vivo MII oosit evreleri arasındaki global DNA metilasyonu farkı immünofloresan yöntemi kullanılarak incelendi. Bu amaçla GV ve MII aşamasındaki oositlerde 5-metil sitozin (5mC) işaretlemesi sonrası Zeiss LSM-880 Airyscan konfokal mikroskopta alınan optik kesitlerinden elde edilen görüntülerden Image-J yazılımı kullanılarak hesaplanan sinyal yoğunlukları değerlendirildi.
Bulgular:
Global DNA metilasyonu, 5-metil sitozin (5mC) işaretlemesi sonrası değerlendirildiğinde, GV aşamasındaki oositlerde, çekirdek bölgesinde gözlemlenirken, MII aşamasındaki oositlerde metafaz plağına uygun lokasyonda, olduğu izlendi.
Global DNA metilasyonunun göreceli sinyal yoğunluğu değerlendirildiğinde; MII aşamasında GV aşamasına göre 3,2 katlık istatistiki olarak anlamlı bir azalma olduğu saptandı. Bu azalışın birinci mayoz sonrası DNA miktarındaki azalmaya bağlı olup olmadığı için yapılan hesaplamalar da bunun sadece DNA miktarındaki azalmadan kaynaklanmadığını gösterdi.
Sonuç:
Oositlerde, GV aşamasına kıyasla MII evresinde global DNA metilasyon seviyesinin üç kattan daha fazla azalmış olması, fertilizasyon öncesi oositteki DNA metilasyonunun çeşitli mekanizmalarla kontrol edildiğini ve bunun fertilizasyon dinamiğinde önemli olabileceğini göstermiştir.
importância das representações cartográficas no ensino de Geografia escolar do fundamental II
Authors: Penha Francimar , Cintra Danielle 
Published: January 2024

Contexto: Por meio dos resultados obtidos a partir da pesquisa3 produzida sobre a relevância da utilização das Representações cartográficas no ensino pelos professores de Geografia durante foi possível compreender que as representações são ferramentas de análise espacial geográfica capazes de transformar a abordagem metodológica de ensino da Geografia escolar, sintetizando os conteúdos disciplinares de forma dinâmica e facilitando o entendimento dos alunos sobre os processos e fenômenos socioespaciais. Metodologia: O trabalho foi realizado a fim de fortalecer o debate sobre o vínculo destas ferramentas com o processo de ensino e aprendizagem dos conteúdos escolares da disciplina de Geografia. Para a pesquisa foi adotada uma abordagem qualitativa que visava a produção de uma argumentação dialética sobre a necessidade constante de reavaliação da sua prática educativa do docente e da implementação das representações no seu planejamento de aulas caso fosse inexistente ou pouco utilizada. Considerações: O principal objetivo foi o de gerar uma discussão sobre a importância do uso das Representações cartográficas na explicação de conteúdos disciplinares de Geografia do ensino fundamental II. Considerando os dados foi possível concluir que existe um caminho árduo a ser percorrido pelo professor de Geografia na busca pela construção do conhecimento geográfico crítico e reflexivo de seus alunos e que sozinho este profissional não atenderá a todas as demandas e problemáticas encontradas durante o processo educativo.
La traducción teatral como discurso social durante los primeros 7 años de dictadura en el TEUC1
Authors: Pelegri Andrea 
Published: January 2024

En este ensayo se aborda la problemática de la traducción entendida como una práctica discursiva, atendiendo, de manera
específica, a un objeto material delimitado: el repertorio de traducción de textos dramáticos realizados para el Teatro de
Ensayo UC (actual Teatro UC) vinculado a los siete primeros años de la dictadura en Chile (1973-1980).
A 50 años de un homenaje: fragmentos de la dictadura en el Departamento de Teatro de la Universidad de Chile
Authors: Centro de Investigación, Archivo y Documentación Teatral Centro de Investigación, Archivo y Documentación Teatral 
Published: January 2024

En septiembre de este año, en el marco de la conmemoración de los 50 años del golpe militar, se inauguró un espacio de
memoria en homenaje a estudiantes asesinados en dictadura que egresaron del Departamento de Teatro de la Universidad
de Chile. Para esto, en el patio Germán Droghetti, se instalaron pendones con breves reseñas correspondientes a los estudiantes
de Actuación Teatral: Ismael Chávez, Ana María Puga y Víctor Jara.