bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of amifostine on apoptotic inflammatory makers in cisplatin induced brain damage in rats
Authors: Masoud Mahmoud M. , El-Laithy Nabila A. , Youness Eman R. , Ahmed Nadia M. , Mahdy Elsayed M.E. , Shousha Wafaa Gh 
Published: January 2025

Abstract

Objectives
To lessen the negative effects of the medication, we assessed the neuroprotective impact of amifostine nanoparticles against the neurotoxicity generated by cisplatin.

Methods
60 adult male albino Wistar rats were arranged into six groups. Group 1; received saline intraperitonealy (IP) and served as negative control. Group 2; received IP injection of silica nano-emulsion, Group 3 received cispatin for three consecutive days at the end of the study, Group 4 received amifostine intrapretonealy (IP) before cisplatin injection, Group 5 received silica nano-emulsion alone for one month, group 6 received silica nano-emulsion in combination with cisplatin for three consecutive days at the end of the study.
Monocyte chemoattractant protein-1 (MCP-1) and glial fibrillary acidic protein (GFAP) were estimated by ELISA, butrylcholinesterase (BChE) by spectrophotometric method while caspase-3 as a marker of apoptosis by PCR.

Results
The mean levels of brain GFAP, MCP-1, and caspase-3 in the cisplatin group were considerably higher than those in the control group. However, there was a drop in the average level of brain BChE activity. Additionally, the injection of (SiNPs@AMF + cisplatin) increased BChE activities while reducing GFAP, MCP-1, and caspase-3 levels, thereby reversing the negative effects of cisplatin on the brain tissue. On the other hand, the group treated with SiNPs@AMF + cisplatin showed improvement in overall brain structure and minimal pyknotic nuclei and apoptotic neurons were found.

Conclusions
These outcomes demonstrated amifostine’s ability to lessen the histological changes brought on by cisplatin. To sum up, SiNPs@AMF may be a suitable and secure supplemental treatment agent to lessen cisplatin’s toxicity in the brain and enhance the treatment’s effects throughout chemotherapy.
Regularization method and a posteriori error estimates for the two membranes problem
Authors: Bouchlaghem Mohammed , Mermri El Bekkaye , Mellah Zhor 
Published: January 2025

Abstract
This study presents a regularization method for the two membranes problem with non-homogeneous boundary conditions. We establish both convergence results and a priori estimates for this method. Using duality theory from convex analysis, we identify the dual problem related to the two membranes problem. Based on this dual formulation, we give a posteriori error estimates for both the continuous and discrete versions of the problem. These a posteriori error estimates are crucial for the practical implementation of the regularized problem.
Nanotechnology of colour: quantum dots (QDs), photonic crystals (PCs) and plasmonic nanoparticles
Authors: Das Udita , Das Ankita , Das Ruhi , Das Asim Kumar 
Published: January 2025

Abstract
This tutorial min review discusses the important features of nanotechnology of colour generation by the quantum dots (QDs), nanostructured photonic crystals (PCs) and plasmonic metal nanoparticles. Quantum dots (QDs) are characterized by the tunable and size dependent strong fluorescence emission properties. Photonic crystals (PCs) generate the material independent structural colour (
iridescent colour dependent on the angle of observation
) due to the constructive interference arising from Bragg diffraction by the nanostructured photonic crystals (PCs) producing the diffraction gratings. It causes the vibrant colour in the opals and pearls, wings of peacocks and butterflies, in the necks of pigeons, variable colours in chameleons, etc. Plasmonic nanoparticles like Au-, Ag- and Cu-nanoparticles show the both light absorption and scattering properties that can be tuned by varying the size, morphology and composition of the nanoparticles. Structural colour (
iridescent colour
) by PCs is used by nature while colouring by QDs and plasmonic nanoparticles are due to the man made activities. The nanotechnology based colour is superior to the organic pigment based colour in terms of brightness and photostability and this field is an emerging area of research with a great promise in terms of applications in various fields.
Stellate ganglion block in disparate treatment-resistant mental health disorders: A case series
Authors: Niraj G. , Karanth V. , Niraj S. , Charan N. 
Published: January 2025

Abstract

Objectives
A significant subset of patients with mental health disorders (MHDs) fail to respond to standard management and are termed as treatment-resistant. This cohort has limited options for managing their condition. Autonomic dysfunction has been reported in the neurobiology of MHDs including anxiety, depression, obsessive-compulsive disorder (OCD), panic disorder, and bipolar disorder (BD). Stellate ganglion block (SGB) is an emerging treatment that dampens sympathetic activity and has been shown to be of benefit in the management of post-traumatic stress disorder.

Methods
Patients with treatment-resistant disparate MHDs were reviewed by a multidisciplinary team comprising a psychiatrist, a clinical psychologist, and a pain medicine physician. Patients were offered SGB as a novel strategy in the management of treatment-resistant conditions. Validated outcome measures were completed at baseline, 4 weeks, and 16 weeks post-intervention.

Results
Four patients with heterogenous treatment-resistant MHDs who received SGB are presented in this report. SGB resulted in an improvement in BD, OCD with alcohol addiction, opioid addiction, and health anxiety.

Conclusion
SGB could have a role in the management of treatment-resistant MHDs.
Derecho y Posibilidad de Futuro
Authors: Mora-Sifuentes Francisco M. 
Published: January 2025

La entrevista forma parte del proyecto El retorno de la crueldad en el Derecho, aprobado por la Dirección de Investigación y Posgrado de la Universidad de Guanajuato en su Convocatoria de Apoyo a Profesores 2024–Modalidad Grupal “G” (Comité Organizador: Dr. Eduardo Pérez Alonso, Dr. Leandro Eduardo Astrain Bañuelos y Dr. Francisco M. Mora-Sifuentes).
Mapping eye, arm, and reward information in frontal motor cortices using electrocorticography in non-human primates
Authors: Ouchi Tomohiro , Scholl Leo R. , Rajeswaran Pavithra , Canfield Ryan A. , Smith Lydia I. , Orsborn Amy L. 
Published: January 2025

Goal-directed reaches give rise to dynamic neural activity across the brain as we move our eyes and arms, and process outcomes. High spatiotemporal resolution mapping of multiple cortical areas will improve our understanding of how these neural computations are spatially and temporally distributed across the brain. In this study, we used micro-electrocorticography (µECoG) recordings in two male monkeys performing visually guided reaches to map information related to eye movements, arm movements, and receiving rewards over primary motor cortex, premotor cortex, frontal eye field, and dorsolateral pre-frontal cortex. Time-frequency and decoding analyses revealed that eye and arm movement information shifts across brain regions during a reach, likely reflecting shifts from planning to execution. Although eye and arm movement temporally overlapped, phase clustering analyses enabled us to resolve differences in eye and arm information across brain regions. This analysis revealed that eye and arm information spatially overlapped in motor cortex, which we further confirmed by demonstrating that arm movement decoding performance from motor cortex activity was impacted by task-irrelevant eye movements. Phase clustering analyses also identified reward-related activity in the pre-frontal and premotor cortex. Our results demonstrate µECoG’s strengths for functional mapping and provide further detail on the spatial distribution of eye, arm, and reward information processing distributed across frontal cortices during reaching. These insights advance our understanding of the overlapping neural computations underlying coordinated movements and reveal opportunities to leverage these signals to enhance future brain-computer interfaces.Significance statementPicking up your coffee mug requires coordinating movements of your eyes and hand and processing the outcomes of those movements. Mapping how neural activity relates to different functions helps us understand how the brain performs these computations. Many mapping techniques have limited spatial or temporal resolution, restricting our ability to dissect computations that overlap closely in space and time. We used micro-electrocorticography recordings to map neural activity across multiple cortical areas while monkeys made goal-directed reaches. These measurements revealed high spatial and temporal resolution maps of neural activity related to eye, arm, and reward information processing. These maps reveal overlapping neural computations underlying movement and open opportunities to use eye and reward information to improve therapies to restore motor function.
Hábito lector del estudiantado de la Facultad de Ciencias y Humanidades de la Universidad de El Salvador
Authors: Viegas Guillem Josefa Antonia 
Published: January 2025

This study examines reading behavior from five perspectives, including self-perception of reading, reading behavior, access to reading, reading interests, and context, among students at the University of El Salvador's Faculty of Sciences and Humanities. It was carried out using the quantitative method, where a questionnaire technique was applied (an adaptation of the one used by CEPLI at the University of Castilla La Mancha). The results reveal that the students have the skills needed for reading and provide a picture of habitual readers, but their reading habits don’t necessarily reflect a general interest in leisure reading. Digital is typically used as a reading aid. Different gender traits are identified in relation to self-perception of reading, reading behavior, and reading interests. However, there is a small proportion of students that read in a daily and academic environment that does not support reading.
Aspectos do Conto Mínimo e da Cena Teatral em Fernando Bonassi
Authors: Oliveira Letícia Mendes de 
Published: January 2025

Este ensaio examina o conceito de conto mínimo através da análise de três obras do escritor Fernando Bonassi: 100 histórias colhidas na rua, 100 coisas e Passaporte. Através do cotejamento entre as linguagens literária e teatral, formulamos uma relação entre conto e cena.
Figurações da Leitura
Authors: Vasconcellos Lisa Carvalho 
Published: January 2025

Em Grande sertão: veredas, vemos um narrador-protagonista relatar sua juventude a um desconhecido. O homem de fora — que denominamos aqui narratário — já foi associado, sem muito desenvolvimento, a um protótipo de leitor, por parte significativa da crítica rosiana. É essa a analogia que pretendemos levar a cabo no presente trabalho, partindo da hipótese de que o estudo do papel desse narratário nos permitiria apresentar figurações da leitura.
Ekphrasis in Shawna Lemay
Authors: Santos Ariane Souza 
Published: January 2025

The object of analysis of this paper concerns the majority of the poems from All the God-Sized Fruit, written by the Canadian poet Shawna Lemay. The poems were built following five ekphrastic frameworks: appropriation of artistic style, process of creation, critical analysis, narrative, and dialogue. The intertwinement of these frameworks with discussions about the processes of writing and painting helps the poet to build up her identity as woman, poet and woman-poet.
Do Texto à Cena
Authors: Silva Daniel Furtado Simões da 
Published: January 2025

A partir das noções de tradução e de transtextualidade examinamos a transposição de textos literários de Caio Fernando Abreu para a cena teatral. Essa transposição estrutural e estilística configura diferentes regimes da narratividade, que implicam em deslocamentos do eixo da narrativa teatral, a qual se apóia alternadamente em vários sistemas semiológicos à disposição do encenador.
<i>Úrsula</i>
Authors: Oliveira Adriana Barbosa de 
Published: January 2025

Neste ensaio, interessa-me analisar em que medida o romance Úrsula, de Maria Firmina dos Reis, diferencia-se da produção literária de seu tempo no que se refere ao ideal nacionalista de uma literatura comprometida com a construção da idéia de nação.
<i>Jekyll and Hyde</i>
Authors: Guedes Rodrigo Silva 
Published: January 2025

This essay analyses the key elements associated to the monster metaphor in Robert Louis Stevenson’s Strange Case of Dr. Jekyll and Mr. Hyde, namely, menace, impurity, freedom, pleasure, and power, based on Noël Carroll’s elaborations. The aim is to study the use of this figure represented by Hyde in the context of a strictly morally oriented Victorian society.
Projeções do antigo
Authors: Silva Elisete E. Ferreira da 
Published: January 2025

Este ensaio aborda, sob o prisma da intertextualidade, a relação entre as odes de Horácio e as de Ricardo Reis. Visando à percepção dos níveis de alcance do intertexto, ressalta a questão das aproximações e dos distanciamentos verificados no processo de apropriação do texto horaciano pelo heterônimo de Fernando Pessoa.
A CRIANÇA ESTRANGEIRA
Authors: Malta Nascimento Josyane Malta 
Published: January 2025

Este trabalho dedica-se a uma reflexão sobre a hospitalidade a partir do pensamento de Jacques Derrida e das memórias de infância do poeta Carlos Drummond de Andrade, especialmente em sua obra poética Boitempo. Pretende-se refletir com poemas dessa obra a relação entre a criança e o adulto como categorias de hóspede e hospedeiro.
Screening for nasal carriage of methicillin resistance Staphylococcus spp. among housekeeping personnel in a tertiary care hospital
Authors: Mistry Yogita , Mullan Summaiya , Gondaliya Nirav , Sarkar Kristi , Kanani Komal 
Published: January 2025

Background: Methicillin resistance Staphylococcus aureus and coagulase negative Staphylococci are commonly isolated pathogens from nosocomial infections. Colonized hospital personnel may be an important factor in dissemination of infection to patients and vice- versa. Among the various cadres of healthcare workers, housekeeping personnel are the most significant source of pathogen dissemination compared to other hospital staff, such as doctors, nurses, and lab technicians. This study aimed to determine the rate of methicillin-resistant Staphylococcus spp. colonization among housekeeping personnel at a tertiary care institute.
Methods: This study was a prospective study. Approximately 150-200 Housekeeping personnel were working in Hospital setting at the time of study period. Those with upper respiratory tract infections and those with history of intake of antibiotics in previous 3 months were excluded. A single nasal swab was used to take the mucosal samples from both the anterior nares by the study investigators.
Results: A total 40 housekeeping personnel had participated and agreed to give nasal samples. Out of 40 Housekeeping personnel nasal swab, 12 (30%) had shown gram positive cocci in clusters. Out of 12 isolates, only 1 (8%) isolate was Staphylococcus aureus, all other 11 (92%) isolates were Coagulase Negative Staphylococcus. Out of 11 Coagulase Negative Staphylococci, 4 (36%) were MRCoNs. And no MRSA found in housekeeping personnel.
Conclusions: Colonized Housekeeping personnel may be an important factor in the dissemination of infection from them to patients and vice-versa. Policies and guidelines should be framed to create awareness among HCWs regarding the screening methods for the detection and treatment of nasal carriage.
The Effectiveness of Volleyball Exercises on Cognitive Function and Daily Living Skills in Patients with Schizophrenia: A Randomized Clinical Trial
Authors: Poul Maryam Khazaei , Raji Parvin , Gharib Mohammadreza , Faghihzadeh Elham 
Published: January 2025

Background: This study aimed to investigate the effectiveness of volleyball exercises on executive function and daily living skills in schizophrenia.
Methods: In this randomized study, 28 individuals with schizophrenia participated. The intervention was volleyball exercises for two months. The Functional Independence Measure, The Lawton instrumental activities of daily living scale‏, and Loewenstein Occupational Therapy Cognitive Assessment battery tests were used in this study. Repeated measures and effect size were utilized for analysis.
Results: Volleyball exercises improve cognitive function and Activities of Daily Living (ADLs) in the intervention group in the following: group effect, time effect, and group and time interaction. They were significant respectively (p-value1=0.041, p-value2=0.001, p-value3=0.001, Cohen’s d=1.267,1.266), (p-value1=0.001, p-value2=0.001, p-value3= 0.001, Cohen’s d=3.967,3.749). With this intervention, no significant difference was observed between the control and intervention groups in instrumental activities of daily Living.
Conclusion: Volleyball exercises improve executive function and ADLs in individuals with schizophrenia.
Évaluation des filières énergétiques marocaines : Impacts environnementaux et implications pour une transition vers une économie verte
Authors: Bouayad Meryam , Elyoussoufi Lahcen , Mohamed Hamdaoui 
Published: January 2025

L’objet de notre article est de déterminer la relation qui existe entre le modèle de développement basé sur l’option de l’économie verte, son défi énergétique ainsi que ses impacts environnementaux attribuables aux diverses filières énergétiques marocaines. En utilisant la méthodologie des scénarios et les données collectées auprès des organismes nationaux et internationaux, nous avons comparé les impacts environnementaux de ces filières sur l’ensemble de l’économie marocaine en les classant les unes par rapport aux autres, en mettant l'accent sur des critères tels que les émissions de CO2 et de CH4, la modification de l'écosystème, le changement de paysage et les risques pour la santé et la sécurité. Ensuite, et sur la base de ce classement, nous avons déterminé les répercussions environnementales de ces filières sur la transition énergétique du modèle de développement basé sur l’option de l’économie verte. Nos résultats montrent qu’en plus de présenter le moins d’impacts environnementaux, les filières hydraulique, solaire et éolienne sont plus durables et produisent un flux d’énergie continue et pratiquement inépuisable. Ils suggèrent qu'un mix énergétique équilibré, intégrant ces trois ressources, est essentiel pour maximiser les avantages socio-économiques et environnementaux.

The purpose of our paper is to determine the relationship between the development model based on the green economy option, its energy challenge, and the environmental impacts attributable to the different Moroccan energy branches. Using the scenario methodology and data collected from national and international organizations, we compared the environmental impacts of these sectors on the Moroccan economy as a whole by ranking them against each other, focusing on criteria such as CO2 and CH4 emissions, ecosystem modification, landscape change, and health and safety risks. Based on this ranking, we then determined the environmental impact of these sectors on the energy transition of the development model based on the green economy option. Our results show that hydro, solar, and wind power not only have the lowest environmental impact but are also more sustainable and produce a continuous and virtually inexhaustible flow of energy. The results suggest that a balanced energy mix integrating these three resources is essential to maximise socio-economic and environmental benefits.
Pratiques pastorales et embroussaillement du pâturage par unité structurale en zone soudanienne : la région de Bouna au Nord-Est de la Côte d’Ivoire
Authors: Kambire Sambi 
Published: January 2025

L’objectif de ces travaux est d’étudier la géologie et l’évolution géomorphologique afin de déterminer le cadre dans lequel s’inscrit la répartition de l’embroussaillement des savanes du Nord-Est ivoirien. On espère, grâce à l’exploitation statistique des divers facteurs d’embroussaillement, aux divers niveaux de l’espace, fournir des éléments de réflexion sur les tendances actuelles du changement dans l’exploitation pastorale des Lobi, ainsi que les blocages ressentis par les aménageurs. L’effet du surpâturage et du feu est mis en évidence dans des parcelles expérimentales à l’échelle toposéquentielle. On notait 2807 rejets sur granite et 1092 sur roches birrimiennes en parcelles surpâturées et protégées contre le feu alors que les parcelles non pâturées mais livrées au feu et celles mises en défens n’en comptaient que moins de 200 dans les deux types de substrat. Le taux des recrus embroussaillants était deux fois plus élevé sur pente que sur sommet et trois fois plus fort sur pente granitique que sur pente en roches birrimiennes.

Study of geology and geomorphological evolution was undertaken in view of distribution of the various encroached vegetation at the scale of landscapes. Statistics in the various factors of encroached vegetation types, at the various levels of space, induce elements for reflection on the current trends of change in the Lobi grazing as well as the blockages felt by the developers. Effects of overgrazing and fires were studied in experimental plots established on the typical catenas of the Bouna region. There were, on average, 2807 shoots of plants on granite and 1092 on phyllitious rocks in the plots grazed and protected from fire, while the plots not grazed but exposed to fire and those protected had less than 200 in both groups of substrates. Rate of brush growth is twice as high on slopes as summits as and three times higher on granite slopes than on slopes on birrimian rocks.
The influence of health-promoting schools on the students’ active and sedentary behaviour
Authors: Valencia-Peris Alexandra , Sanchis-Francés Lucia , Chinchilla-Ramírez Carlos 
Published: January 2025

Physical inactivity and levels of sedentary behaviour among students are associated with health problems, and schools are one of the institutions with the greatest potential for promoting healthy habits. The aim of this study was to compare the levels of physical activity and sedentary behaviour in a sample of schoolchildren according to gender, educational stage, and belonging (or not) to an Active school. A total of 727 students participated (50.3% girls; Mage = 12.8). Two questionnaires were used: the Physical Activity Questionnaire to assess physical activity levels and levels and the Young Leisure Sedentary Behaviour Questionnaire to assess sedentary time. The results show that, regardless of school type: a) the vast majority did not comply with the guidelines, b) boys spent more time in physical activity and screen time than girls, and c) physical activity decreased and screen time increased as students progressed through the educational stage. However, while there were no differences in physical activity according to school type, students who did not belong to an Active school spent more time in sedentary screen time than those who did. These findings call into question the effectiveness of Active schools as a strategy to promote physical activity and reduce sedentary time by eliminating gender and educational stage differences. There is a need to improve intervention approaches in schools to promote holistically healthy and active lifestyles from childhood.