bluuebunny/crossref_metadata_2025_split huggingface dataset:
Subtotal Thigh Flap for Large Abdominal Wall Defect Reconstruction in Patient With Recurrent Dermatofibrosarcoma Protuberans
Authors: Hsieh Pei-Ju , Shi Min-Yen , Pu Chi-Ming 
Published: January 2024

Abstract

Background
Harvesting an adequate-sized flap is challenging for reconstructing large defects on the abdominal wall. A subtotal thigh flap would be one of the choices as it provides a well-vascularized large flap with muscle components. Moreover, dermatofibrosarcoma protuberans (DFSP) is a low-grade dermal neoplasm with a high recurrence rate. There is still no consensus on the extent of resection to prevent a recurrence.

Objectives
We present a case of a patient who underwent the reconstruction of a large abdominal wall defect with a subtotal thigh flap after the resection of recurrent DFSP.

Materials and Methods
A 59-year-old man killed from a recurrent huge mass in the lower abdomen with an invasion of the small intestine. His baseline characteristics and records of operations, medications, and outcomes were reviewed.

Result
After tumor excision, a 28 × 30-cm subtotal thigh flap was harvested from his left thigh to reconstruct the abdominal defect. A microvascular anastomosis with left deep inferior epigastric vessels was made eventually. The flap was in good condition, and the donor site was covered with a split-thickness skin graft.

Conclusions
Subtotal thigh flap may be considered for large abdominal wall defect reconstruction as it allows good perfusion of relatively large skin paddles compared with other free flaps. Also, patients with DFSP need definite margin-free resection and close follow-up to prevent a recurrence.
“Submarine-Shaped” Radial Forearm Flap for Simultaneous Reconstruction of Oral and Lower Lip Defects”
Authors: Ribeiro Luis Mata , Peng Chi , Mustafa Al , Cheong David Chon-Fok , Hung Shao-Yu , Tsao Chung-Kan 
Published: January 2024

Background
Reconstruction of the oral cavity commonly results in trismus and lip incompetence.

Aim and Objectives
In this study, we aim to describe an innovative design of a radial forearm free flap for resurfacing bilateral buccal defects and simultaneous functional lower lip reconstruction in a single stage.

Materials and Methods
Between January 2010 and December 2019, 6 males underwent simultaneous buccal and lower lip reconstruction with a radial forearm free flap. The mean age of the patients was 57.3 years (range, 50–68 years). The defects were caused by trismus release and due to previous treatments. The mean size of the defects was 17.9 cm in length and 3.25 cm in width. Flaps were harvested, including the proximal perforators of the radial vessels, and the inset began in the buccal area opposite the anastomosis side.

Results
Flap size ranged from 16 to 21 × 2 to 4 cm. The recipient vessels used were the superficial temporal (4) and facial (2). All flaps survived. Lip infection was seen in 2 cases and managed conservatively. The mean follow-up was 19.2 months (range, 12–28 months). The mean increase in the interincisal distance was 10.7 mm. Oral continence was good in all patients. Speech intelligibility was considered total in 4 patients and partial in the remaining 2.

Conclusion
The radial forearm flap constitutes an option for simultaneous lower lip reconstruction and resurfacing of bilateral buccal areas after trismus release. The procedure provides a thin and pliable reconstruction using only 1 donor site and 1 set of recipient vessels.
Deep Learning Outperforms Classical Machine Learning Methods in Pediatric Brain Tumor Classification through Mass Spectra
Authors: Santos Bezerra Thais Maria , Silva de Deus Matheus , Cavalaro Felipe , Ribeiro Denise , Seidinger Ana Luiza , Cardinalli Izilda Aparecida , de Melo Porcari Andreia , de Souza Queiroz Luciano , Pedrini Helio , Meidanis Joao 
Published: January 2024

AbstractPediatric brain tumors are the most common cause of death among all childhood cancers and surgical resection usually is the first step in disease management. During surgery, it is important to perform safe gross resection of tumors, retaining as much brain tissue as possible. Therefore, appropriate resection margin delineation is extremely relevant.Currently available methods for tissue analysis have limited precision, are time-consuming, and often require multiple invasive procedures. Our main goal is to test whether machine learning techniques are capable of classifying the pediatric brain tissue chemical profile generated by DESI-MSI, which is mainly lipidic, into normal or abnormal tissue and into low- and high-grade malignancy subareas within each sample.Our experiments show that deep learning methods outperform classical machine learning methods in the task of classifying brain tissue from DESI-MSI mass spectra, both in normal versus abnormal tissue, and, for malignant tissues, in low-grade versus high-grade malignancy.Our conclusion are based on the analysis of 34,870 annotated spectra, obtained from the neoplastic and non-neoplastic microanatomical stratification of individual samples from 116 pediatric patients who underwent brain tumor surgical resection at the Boldrini Children’s Center between 2000 and 2020. Support Vector Machines, Random, Forests, and Least Absolute Shrinkage and Selection Operator (LASSO) were among the classical machine learning techniques evaluated.
Artificial-Intelligence Powered Identification of High-Risk Breast Cancer Subgroups Using Mammography: A Multicenter Study Integrating Automated Brightest Density Measures with Deep Learning Metrics
Authors: Jeong Yeojin , Lee Jeesoo , Lee Young-jin , Hwang Jiyun , Lee Sae Byul , Yoo Tae-Kyung , Kim Myeong-Seong , Kim Jae Il , Hopper John L , Nguyen Tuong L , Lee Jong Won , Sung Joohon 
Published: January 2024

AbstractMammography plays a crucial role in breast cancer (BC) risk assessment. Recent breakthroughs show that deep learning (DL) in mammography is expanding from diagnosis to effective risk prediction. Moreover, the brightest mammographic breast density (MBD), termed “cirrocumulus,” signifies an authentic risk. Addressing the challenges in quantifying above recent measures, we present MIDAS: a DL-derived system for multi-level MBD and risk feature score (FS). Using >260,000 multicenter images from South Korea and the US, FS consistently outperforms conventional MBD metrics in risk stratification. Only within the high FS, cirrocumulus further enriches assessment, pinpointing “double-higher” subgroup. Their risk profiles are notable: women in double upper-tertile showed OR=10.20 for Koreans and 5.67 for US, and OR=7.09 for scree-detected cases (US only). We also reveals the “black-box” nature of FS that it predominantly captures complex patterns of higher-intensity MBD. Our research enhances the potential of digital mammography in identifying individuals at elevated BC risks.
Model for measuring competitiveness in construction companies in Lima–Peru
Authors: Tam Wong Fernando Luis , Castro Guzman Enrique Alonso , Franco Chalco Eduardo 
Published: January 2024

PurposeThe main objective of this study was to establish a model of competitiveness factors to measure the value of construction companies adequately.Design/methodology/approachA theoretical model of four main factors was developed, and they include human capital, ethical values, process innovation and financing. Information was collected from 18 construction companies in the city of Metropolitan Lima, collecting information on each of these factors. Through an analysis of the principal components, the weighting of each factor about the competitiveness of a construction company was determined.FindingsThe cost of person-hours, the cost of equipment to execute work, and the cost of materials used are the strongest indicators to measure the competitiveness of a construction company. On the other hand, the number of employees holding university degrees and the number of master builders holding technical degrees in the human capital factor also have a moderate weight in determining the competitiveness value of a company. The indicator of work delivered within the deadline also moderately affects competitiveness. Finally, the monthly debt payment indicator has a very small effect on the company’s competitiveness.Originality/valueIn conclusion, this study provides evidence of a competitiveness model with highly related factors on human capital, process innovation and ethical values as the most important in measuring competitiveness.
Exploring the relationships between knowledge management enablers, employee innovativeness and market development performance in A/E/C firms: a developing country perspective
Authors: Dang Chau Ngoc , Wipulanusat Warit , Nuaklong Peem , Witchayangkoon Boonsap 
Published: January 2024

Purpose
This study aims to explore the relationships between knowledge management (KM) enablers, employee innovativeness (EI) and market development performance (MDP) in architecture, engineering and construction (A/E/C) firms.

Design/methodology/approach
A questionnaire survey is conducted to collect empirical data from A/E/C practitioners in Vietnam. First, factor analysis is used to identify KM enablers in A/E/C firms. Then, a framework which shows the links between KM enablers, EI and MDP is proposed. Structural equation modeling (SEM) is used to examine the proposed relationships.

Findings
This study identifies five constructs which can enable A/E/C firms to achieve effective KM implementation, including mutual trust and collaboration, organizational values and norms, information and communication systems, organizational policies and empowerment. Furthermore, the SEM results show that except for organizational policies, four remaining KM enablers significantly affect EI. It is also found that EI has a significant impact on MDP.

Practical implications
The findings could help A/E/C firms to know which KM enablers are critical to EI and provide a better understanding of the link between EI and MDP. Hence, they could make appropriate investments in KM practices to improve both EI and MDP.

Originality/value
The results of this study fill the gap in knowledge by empirically structuring the relationships between KM enablers, EI and MDP. Such results may provide A/E/C firms with useful information to enhance EI and MDP in today’s intensively competitive construction environments.
How do different management control configurations influence construction safety professionals' work attitudes
Authors: Ju Chuanjing , Ning Yan , Shen Yuzhong 
Published: January 2024

PurposeSafety professionals' primary job is to execute safety control measures towards frontline personnel, and previous studies focus on the effectiveness of such controls. Rare research efforts, however, have been devoted to the effectiveness of management control measures towards safety professionals themselves. This study aimed to fill up this knowledge gap by examining whether safety professionals under differing management control configurations differ in their work attitudes, including affective commitment, job satisfaction, career commitment and intention to quit.Design/methodology/approachDrawing on a holistic view of control, five forms of management control, i.e. outcome control, process control, capability control, professional control and reinforcement, were investigated. A cross-sectional questionnaire survey targeting at construction safety professionals was conducted. The latent profile analysis approach was employed to identify how the five forms of management control are configured, i.e. identifying the distinctive patterns of control profiles. The Bolck–Croon–Hagenaars method was then used to examine whether safety professionals' work attitudes were different across the identified control profiles.FindingsSeven distinct control profiles were extracted from the sample of 475 construction safety professionals. The overall test of outcome means showed that mean levels of affective commitment, job satisfaction and intentions to quit were significantly different across the seven profiles. The largest that was also the most desirable subgroup was the high control profile (n = 161, 33.9%). The least desirable subgroups included the low control profile (n = 75, 15.8%) and the low capability and professional control profile (n = 12, 2.5%). Pairwise comparison suggested that capability, professional and process controls were more effective than outcome control and reinforcement.Originality/valueIn theory, this study contributes to the burgeoning literature on how to improve the effectiveness of control measures targeted at safety professionals. The results suggested that effective management controls involve a fine combination of formal, informal, process and output controls. In practice, this study uncovers the ways in which managers leverage the efforts of safety professionals in achieving safety goals. Particularly, it informs managers that the control configurations, instead of isolated controls, should be executed to motivate safety professionals.
Philosophy of science and research paradigm for business research in the transformative age of automation, digitalization, hyperconnectivity, obligations, globalization and sustainability
Authors: Lim Weng Marc 
Published: January 2024

PurposeThis article aims to explain the role of philosophical anchors and research paradigms in business research, and how they can be extrapolated in the transformative era of automation, digitalization, hyperconnectivity, obligations, globalization and sustainability (ADHOGS) in the midst of disruption, volatility, uncertainty, complexity and ambiguity (DVUCA).Design/methodology/approachThis article entails a general review based on the 3Es of exposure, expertise and experience, delving into the ontological, epistemological, methodological, axiological and rhetorical aspects of the major research paradigms—i.e. positivism, post-positivism, constructivism, interpretivism and pragmatism—and their interplay with the emergent trends shaping business research.FindingsThis article underscores the multifaceted nature of business research in the modern day, with an increasing need for blending, or shifting between, research paradigms to address the complex issues arising from automation, digitalization, hyperconnectivity, obligations, globalization and sustainability (ADHOGS). This article also highlights the nuanced interplay between research paradigms and theoretical perspectives, demonstrating the rich, diverse potential of business research inquiries.Research limitations/implicationsWhile this article provides a broad overview of the interplay between research paradigms and emerging trends, future research could explore each of these interplays in greater detail, conducting empirical studies or utilizing specific case studies.Practical implicationsResearchers and practitioners should be open to adopting, combining or switching between different paradigms according to the demands of their research questions, context and trends shaping the business landscape, thereby underscoring the need for methodological flexibility and reflexivity in business research.Social implicationsThe shift toward embracing digital transformations and integrating sustainability in business research holds significant implications, driving socially responsible and sustainable business practices at the micro-level, and by extension, industrial revolution and sustainable development at the macro-level.Originality/valueThis article offers a holistic and contextualized view of the philosophy of science and research paradigms for business research, bridging the gap between philosophical foundations and contemporary research trends.
Abusive supervision and psychological well-being: the mediating role of self-determination and moderating role of perceived person-organization fit
Authors: Wang Wenxian , Kang Seung-Wan , Choi Suk Bong , Jeung Wonho 
Published: January 2024

PurposeToday, psychological well-being is increasingly valued by organizations because it is integral to employee performance. The style of leaders supervising their subordinates is an important influence on their psychological well-being. Abusive supervision can lead to a depletion of resources among their subordinates by inducing psychological stress, leading to a decline in psychological well-being. In this research, the authors use the conservation of resources (COR) theory and self-determination theory to examine the mechanism between abusive supervision and psychological well-being. This study can contribute to previous research by applying the COR theory and self-determination theory, which were not discussed, to explain the relationship between leader's leadership behavior and psychological well-being of organizational members.Design/methodology/approachThe authors conduct a multi-time data collection method of two waves with six-week intervals. The authors received 322 samples and conducted a confirmatory factor analysis to test result validity and used multiple regression to examine the direct and moderating effects. Additionally, the authors used the bootstrapping method to test mediating effects.FindingsThe results show that abusive supervision is negatively related to psychological well-being and self-determination plays the mediating role between them, while perceived person-organization fit is the moderator between self-determination and psychological well-being.Originality/valueThe authors identified self-determination as the mediator between abusive supervision and psychological well-being and perceived person-organization fit plays the moderating role between self-determination and psychological well-being.
Should SMEs diversify their global destinations? The role of market insights and digital transformation
Authors: Luu Tien Dung 
Published: January 2024

PurposeThis study aims to investigate the relationship between geographic diversification (GD) and export performance (EP) by analysing a sample of small exporters in an emerging market.Design/methodology/approachThe study sample comprised 96 small and medium-sized exporting enterprises (SMEs) in Vietnam. The data is analysed using multiple regression analysis (MRA), Hayes' process model and fuzzy-set qualitative comparative analysis (fsQCA).FindingsThe results indicate that GD significantly negatively affects EP. In this dilemma, the export market orientation (EMO) and digital transformation positively moderated the relationship between GD and EP, such that the negative effect of GD on EP was weaker when EMO and digital were stronger.Originality/valueThis initial study contributes significantly to international business theories and practices, which reveal the role of GD via firm digital capacity and EMO in thriving SMEs’ EP. This study might grant new insight into international business and a critical approach to addressing the new insights small firms may face in a fragile but technologically advanced world.
Domain‐general and reading‐specific cognitive flexibility and its relation with other executive functions: Contributions to science text reading comprehension
Authors: Escobar José‐Pablo , Meneses Alejandra , Hugo Evelyn , Barber Ana Taboada , Montenegro Maximiliano 
Published: January 2024

BackgroundCognitive and linguistic factors have been incorporated into models to explain reading comprehension beyond classical models of reading. This study explores the contribution of executive functions, mainly domain‐general and reading‐specific cognitive flexibility, in reading comprehension of science texts in monolingual Spanish speaking upper elementary students.MethodsA total of 275 Chilean students from fourth to sixth grade participated in this study. They were evaluated in working memory, inhibition, reading fluency, domain‐general and reading‐specific cognitive flexibility, academic vocabulary and science reading comprehension.ResultsThe results show that cognitive flexibility is a variable that explains performance in science reading comprehension across elementary grades. Furthermore, reading domain‐specific cognitive flexibility was found to be the variable that explains additional performance in science reading comprehension above inhibition, reading fluency, academic vocabulary and domain‐general cognitive flexibility in Grade 4 and Grade 5, but not in Grade 6.ConclusionsThese results suggest the contribution of cognitive variables such as cognitive flexibility in explaining performance in reading comprehension of science texts. The need to develop cognitive tests specific to reading domain is also discussed.
Circular RNA expression profile and functional analysis of circUvrag in light‐induced photoreceptor degeneration
Authors: Kong Kangjie , Ding Xinyi , Wang Yingchao , Xu Sisi , Li Gang , Wang Xin , Zhang Meng , Ni Yingqin , Xu Gezhi 
Published: January 2024

AbstractBackgroundCircular RNAs (circRNAs) are implicated in retinal pathophysiology; however, their expression profiles and functions in photoreceptor apoptosis are largely unknown. We explored circRNA‐expression profiles and circUvrag (host gene: Uvrag, ultraviolet radiation resistance associated gene) function in light‐induced photoreceptor apoptosis.MethodsSprague–Dawley rats and 661 W photoreceptor cells were exposed to blue light to establish light‐induced photoreceptor degeneration. Differentially expressed circRNAs were identified using microarrays. Potential functions of dysregulated circRNAs were analysed using Gene Ontology and Kyoto Encyclopedia of Genes and Genomes analyses. CircUvrag expression and localization were evaluated using quantitative RT‐PCR and fluorescence in situ hybridization, respectively. CircUvrag overexpression and knockdown were induced using a plasmid and a small interfering RNA, respectively, and retinal function and structure were assessed using scotopic electroretinography, haematoxylin–eosin staining, and TUNEL staining. Microglial migration was assessed using IBA1 immunostaining. The apoptosis ratio of photoreceptor cells in vitro was detected using flow cytometry.ResultsWe identified 764 differentially expressed circRNAs, which were potentially related with the development of retinal structures, including neurons, dendrites, and synapses, and might participate in nervous‐system pathophysiology. Light exposure enriched circUvrag in the cytoplasm of photoreceptors in the outer nuclear layer (ONL). CircUvrag knockdown decreased photoreceptor apoptosis and microglial migration to the ONL after light exposure, preserving ONL thickness and a‐wave amplitude. In vitro, circUvrag knockdown inhibited photoreceptor apoptosis, although circUvrag overexpression slightly promoted photoreceptor apoptosis.ConclusionsCircUvrag knockdown attenuated light‐induced photoreceptor apoptosis, and might be a potential target in retinal degeneration.