bluuebunny/crossref_metadata_2025_split huggingface dataset:
The quality and content analysis of YouTube videos about chemotherapy for children
Authors: Semerci Remziye , Şimşek Enes , Savaş Eyşan , Orhan Eda , Erbey Fatih 
Published: January 2024

AbstractPurposeThis study undertook a systematic examination of YouTube videos about chemotherapy for pediatric patients, with a primary focus on assessing the videos' quality, content, and reliability.MethodThe research was conducted by searching YouTube using the keywords “chemotherapy for children” and “chemotherapy for pediatric,” employing filters for “worldwide” and “all categories.” The top 100 videos, based on popularity, were selected for evaluation according to the power analysis calculation. Two independent experts in pediatric oncology reviewed these videos. Video characteristics were recorded: length, view count, likes, dislikes, view ratio, and video‐like ratio. The Video Power Index was calculated to measure video popularity. The modified DISCERN and Global Quality Scale (GQS) assessed the videos for quality and reliability.ResultsThe 100 videos were analyzed. Official health institutions uploaded 54%, while independent users contributed 46%. Independent user uploads garnered significantly more views than official health institutions (p = .006). The number of likes, view ratio, and Video Power Index of independent users’ videos were significantly higher than official health institutions’ videos (respectively, p = .007, .007, and .008). On the other hand, the modified DISCERN score and GQS were significantly higher in YouTube videos of official health institutions than in independent users (p < .001). A strong correlation was observed between the modified DISCERN score and GQS (r = .879, p < .001).ConclusionThis study provides valuable insights into the YouTube videos on pediatric chemotherapy, emphasizing the need to improve the quality and reliability of online health information for this vulnerable population.
High‐velocity impact resistance of the carbon fiber composite grid sandwich structures
Authors: Wei Shiyi , Guo Zhangxin , Niu Weijing , Chai Gin Boay , Tai Zhe , Li Yongcun 
Published: January 2024

AbstractThe carbon fiber composite grid sandwich structure represents an innovative category of lightweight composite sandwich structures, showcasing remarkable attributes including reduced weight, high‐specific strength, exceptional specific stiffness, and robust design flexibility. Using ABAQUS, the high‐velocity impact performance of carbon fiber composite grid sandwich structure is numerically simulated. This study delved into examining the impact patterns arising from various factors, including the equivalent density, height, and geometric configuration of the core layer. Additionally, the effects of the impact punch's initial velocity, size, and impact position on the high‐speed impact resistance performance of the carbon fiber composite grid sandwich structure were explored. The fracture absorption work of the structure and the kinetic energy attenuation rate of the impact punch are positively correlated with the equivalent density, height of the structural core layer, as well as the initial velocity and dimensions of the impact punch. Notably, the square carbon fiber composite grid sandwich structure was most significantly influenced by the equivalent density of the core layer, while the mixed carbon fiber composite grid sandwich structure was most sensitive to variations in core layer height and punch size. When impacted at the intersection of the ribs, compared with the central position between the two ribs, the structure shows enhanced fracture absorption energy and greater impact kinetic energy attenuation rate.Highlights
The structure was modeled based on the interlocking assembly process.
The high‐velocity impact resistance of the structure was studied.
Different structural parameters were designed for the core layer to study.
The initial velocity, size and impact position of the punch were involved.
Electrospun polyvinylidene fluoride with novel facile synthesized functionalized boron nitride quantum dots for neural applications
Authors: Ekram Basma , Trueman Ryan P. , Phillips James B. , Ros Helena , Abd El‐Hady Bothaina M. , El‐Gendy Dalia M. 
Published: January 2024

AbstractThe study aimed to develop a potential biomaterial for neuroregeneration by the electrospinning of the biocompatible polymer polyvinylidene fluoride (PVDF) with innovative functionalized boron nitride quantum dots (F‐BNQDs) synthesized via green chemistry using the amino acid taurine as a functionalization. The F‐BNQDs were characterized and were found to be 16–21 nm in diameter, showed good photoluminescent characteristics, and their elemental composition was confirmed by x‐ray photoelectron spectroscopy, Fourier‐transform infrared (FTIR), and ultraviolet spectroscopy. The PVDF with F‐BNQDs was prepared at three different concentrations, and the resulting electrospun fibers were characterized by scanning electron microscopy, FTIR, thermogravimetric analysis, contact angle, biodegradation, water uptake, Schwann cell cytotoxicity, and cell behavior studies. The results of the study showed that the addition of F‐BNQDs to PVDF resulted in enhanced mechanical properties, decreased contact angle, increased degradability, and water uptake. The lactate dehydrogenase assay revealed that 5% BN‐PVDF had the lowest cytotoxicity. Fluroscent 4',6‐diamidino‐2‐phenylindole (DAPI) staining showed that the increase in F‐BNQD concentration up to 5% BN‐PVDF enhanced cell behavior on the electrospun fibers. Therefore, the study concluded that 5% BN‐PVDF would be suitable for further testing as a potential biomaterial for neuroregeneration in vivo.Highlights
Functionalized boron nitride quantum dots (F‐BNQDs) were prepared using amino acid taurine.
The F‐BNQDs were characterized and electrospun with polyvinylidene fluoride (PVDF).
The incorporation of F‐BNQDs to PVDF has enhanced its physicochemical properties.
All samples showed a single βphase PVDF.
Schwann cells showed excellent compatibility and cell adhesion on F‐BNQDs/PVDF.
Ethnic–racial socialization experiences of Mexican American youth
Authors: Bingham Katherine J. , Cutrer‐Párraga Elizabeth A. , Smith Timothy B. 
Published: January 2024

AbstractResearch has shown that ethnic–racial socialization (ERS) predicts education and mental health outcomes for adolescents. However, limited research has evaluated the ERS experiences of Latinx students. The current study examined ERS experiences of Mexican American youth in four focus group interviews that were transcribed and analyzed at both the individual and group level using interpretive phenomenological analysis. Main themes included feeling like an outsider, navigating discrimination, encountering social/emotional difficulties, and achieving a positive identity. Each theme contained two to three subcategories that provide further insight into the Mexican Americans' ERS experiences. Participants reported within‐group discrimination, motivation to disprove stereotypes, and infrequent understanding or compassion from adults. Teachers, administrators, counselors, and school psychologists can attend to and seek to promote social connections, implement social‐emotional learning interventions, foster resilience, work to dismantle racism, collaborate with parents, and create communities of inclusion.
Fluorographene and carbon nanotubes fillers reinforced nitrile butadiene rubber with enhanced mechanical, wear and oil resistant properties
Authors: Pang Bo , Luo Entao , Du Meiqing , Kong Lingmin , Zhao Lijuan , Wu Jinrong 
Published: January 2024

AbstractIn this work, we prepared nitrile butadiene rubber (NBR) composites with fluorographene (FG) and carbon nanotubes (CNTs) as hybrid fillers by a solution‐blending method. The resulting composites xFG/yCNTs‐NBR, where x and y represent the loading of FG and CNTs respectively, show significantly improved physical and mechanical properties. The hybrid fillers can form a filler network in the rubber matrix, leading to efficient energy dissipation. As a result, when the mass ratio of FG to CNTs is 1:1 and the total filler loading is 20 phr, the tensile strength of 10FG/10CNTs‐NBR is as high as 12.1 MPa. Furthermore, due to inherent lubricating and oil‐repelling effects of FG, 10FG/10CNTs‐NBR shows an abrasion resistance index (ARI) of 187% and a volume change of 2.38% after 72 h of soaking in aviation oil, which are 24% higher and 48% lower than the corresponding values of unfilled NBR composites, respectively. These results indicate that the hybrid fillers can effectively enhance the mechanical, wear and oil resistant properties of the elastomer composites, which is conductive for application of the NBR‐based composites.
Medicinal herbs consumption in relation to cardiometabolic indices and coronary artery stenosis in participants undergoing coronary angiography: A cross‐sectional study
Authors: Arabi Vahid , Sasanfar Bahareh , Sareban Hassanabadi Mohammad Taghi , Seyedhosseini Seyed Mostafa , Jambarsang Sara , Motallaei Maryam , Taftian Marzieh , Darand Mina , Mirjalili Fatemeh Sadat , Salehi‐Abargouei Amin 
Published: January 2024

AbstractFew studies have investigated the association between herbal medicine consumption and coronary artery disease severity. This cross‐sectional study aimed to investigate the association between the frequency of medicinal herbs consumption and coronary artery stenosis (CAS), lipid profile, fasting blood sugar (FBS), and blood pressure level in participants undergoing coronary angiography. This study was conducted on 662 participants aged 35–75 years. Serum cardiometabolic markers were measured using standard kits. The extent and severity of CAS were evaluated using the Gensini score (GS) and syntax score (SS). Higher consumption of Thymus vulgaris and Sumac was associated with decreased odds of artery‐clogging according to the GS. A higher intake of Thymus vulgaris and Mentha was associated with lower levels of serum cholesterol and triglyceride. Monthly intake of Thymus vulgaris, and weekly/daily intake of Mentha, Nigella Sativa, and Cuminum Cyminum were associated with lower low‐density lipoprotein. Weekly/daily intake of Turmeric and Thymus vulgaris were associated with lower high‐density lipoprotein levels and monthly intake of Mentha was related to lower serum FBS levels. Higher consumption of Mentha, Mentha pulegium L, Lavandula angustifolia, and Nigella Sativa was associated with lower levels of systolic blood pressure. According to the results of the present study, herbs consumption might be related to a reduction in CAS risk factors.
microRNAs associated with the quality of follicular fluids affect oocyte and early embryonic development
Authors: Aoki Sogo , Inoue Yuki , Hara Shunsuke , Itou Jun , Shirasuna Koumei , Iwata Hisataka 
Published: January 2024

AbstractPurposeOocyte and embryo quality differs significantly among individuals. Follicular fluid (FF) is a solo environment of oocyte maturation and may flux into the oviduct. Supplementation of in vitro maturation (IVM) and culture (IVC) medium with extracellular vesicles of FFs supports oocyte maturation and embryonic development. We addressed a hypothesis that miRNA profiles in FFs are crucial background of oocyte maturation and embryonic development.MethodsFFs were collected from the ovaries of individual cows, and the FFs were classified into Good or Poor FF based on the developmental rate to the blastocyst stage of enclosed oocytes. miRNAs associated with the Good FFs were explored using small RNA sequencing. In addition, FFs were classified using the concentration of Good‐FF‐associated miRNAs. These classified FFs or miRNA were added to the IVM or IVC mediums.ResultsSupplementation of IVM and IVC medium with Good FF improved embryonic development. Good FFs contained miR‐151‐3p and miR‐425‐5p at a high concentration compared with those in Poor FFs. FFs selected by the concentration of miR‐151‐3p and miR‐425‐5p improved oocyte maturation and embryonic development. Supplementation of IVM or IVC medium with either miR‐151‐3p or miR‐425‐5p improved embryonic development to the blastocyst stage.ConclusionmiRNAs were associated with the Good FFs determined oocyte maturation and embryonic development.
Integrating role of green buildings in achieving carbon neutrality in an era of climate emergency
Authors: Batool Komal , Ali Ghaffar , Ullah Khan Kaleem , Asif Kamran Muhammad , Yan Ningyu 
Published: January 2024

AbstractThe Intergovernmental Panel on Climate Change recently stated that a swift ecological transition in transport, energy, and construction is required to reach the global emission reduction target. Around 40% of global emissions come from residential and commercial buildings. Therefore, this study developed a green building adoption model based on the Unified Theory of Acceptance and Use of Technology, which encourages firms to implement these novel green building technologies. For this, a survey of 333 respondents from Pakistani construction firms was conducted, and Partial Least Square Structural Equation Modeling approach was applied to validate the study's hypotheses. The findings showed that green building adoption provided invaluable insight by showing the strong associations between green building environmental concern, green building performance expectancy, green building effort expectancy, green building social influence, and green building innovation cost with green building behavioral intentions. Likewise, the findings also showed that green building behavioral intentions play a significant mediating role between the adoption of green buildings and its factors. The findings from this study suggest that intentions to engage in green building activities have a strong direct and mediating effect on green building adoption. Furthermore, the moderating effect of firm size demonstrated the significant differences between small, medium, and large firms size. Based on the study’ findings, the green building adoption model provided novel insights for governments and concerned stakeholders, including construction firms, to adopt green buildings for carbon neutrality in this era of climate emergency.
Hyaluronic Acid – Coated Niosomes for Curcumin Targeted Delivery into Breast Cancer Cells
Authors: Al Zubaidi Zahraa M. , Nsairat Hamdi , Shalan Naeem M. , Al‐Asfoor Leena , Alqudah Dana A. , Mrahleh Mairvat , Alshaer. Walhan 
Published: January 2024

AbstractThis study described a hyaluronic acid (HA) coated niosomes (Nio) encapsulated curcumin (CRM) (CRM‐HA‐Nio) to improve therapeutic properties via targeted delivery. CRM‐HA‐Nio was prepared by thin film hydration method and characterized via dynamic light scattering and transmission electron microscopy. Release assay was performed utilizing dialysis method. Antioxidant, Cell viability, and cellular uptake assays were performed to evaluate the biological activity. CRM‐HA‐Nio has 142.93±39.71 nm size with −20.67±1.10 charge and showed good stability with 93±4.35 % encapsulation efficiency and displayed pH‐independent release pattern. CRM‐HA‐Nio displayed a 2‐fold antioxidant improvement compared to free CRM. CRM‐HA‐Nio showed much better cytotoxic activity on MCF‐7 cell line with IC50of 1.851±0.45 μM compared to free CRM of IC50equal to 5.230±0.85 μM, by approximately 3‐fold enhancement. CRM‐HA‐Nio may be a promising targeted nanocarrier to elucidate targeted bioactivity against cancer when oxidative stress is a major side effect.
Tumor‐Targeting Multiple Metabolic Regulations for Bursting Antitumor Efficacy of Chemodynamic Therapy
Authors: Gao Fan , Dong Jian‐Hui , Xue Chun , Lu Xin‐Xin , Cai Yu , Tang Zi‐Yang , Ou Chang‐Jin 
Published: January 2024

AbstractInterfering with intratumoral metabolic processes is proven to effectively sensitize different antitumor treatments. Here, a tumor‐targeting catalytic nanoplatform (CQ@MIL‐GOX@PB) loading with autophagy inhibitor (chloroquine, CQ) and glucose oxidase (GOX) is fabricated to interfere with the metabolisms of tumor cells and tumor‐associated macrophages (TAMs), then realizing effective antitumor chemodynamic therapy (CDT). Once accumulating in the tumor site with the navigation of external biotin, CQ@MIL‐GOX@PB will release Fe ions and CQ in the acid lysosomes of tumor cells, the latter can sensitize Fe ions‐involved antitumor CDT by blocking the autophagy‐dependent cell repair. Meanwhile, the GOX component will consume glucose, which not only generates many H2O2 for CDT but also once again decelerates the tumor repair process by reducing energy metabolism. What is more, the release of CQ can also drive the NO anabolism of TAMs to further sensitize CDT. This strategy of multiple metabolic regulations is evidenced to significantly improve the antitumor effect of traditional CDT nanoagents and might provide a new sight to overcome the bottlenecks of different antitumor treatments.
Hollow CoFe Nanozymes Integrated with Oncolytic Peptides Designed via Machine‐Learning for Tumor Therapy
Authors: Li Feiyu , Xu Bocheng , Lu Zijie , Chen Jiafei , Fu Yike , Huang Jie , Wang Yizhen , Li Xiang 
Published: January 2024

AbstractDeveloping novel substances to synergize with nanozymes is a challenging yet indispensable task to enable the nanozyme‐based therapeutics to tackle individual variations in tumor physicochemical properties. The advancement of machine learning (ML) has provided a useful tool to enhance the accuracy and efficiency in developing synergistic substances. In this study, ML models to mine low‐cytotoxicity oncolytic peptides are applied. The filtering Pipeline is constructed using a traversal design and the Autogluon framework. Through the Pipeline, 37 novel peptides with high oncolytic activity against cancer cells and low cytotoxicity to normal cells are identified from a library of 25,740 sequences. Combining dataset testing with cytotoxicity experiments, an 80% accuracy rate is achieved, verifying the reliability of ML predictions. Peptide C2 is proven to possess membranolytic functions specifically for tumor cells as targeted by Pipeline. Then Peptide C2 with CoFe hollow hydroxide nanozyme (H‐CF) to form the peptide/H‐CF composite is integrated. The new composite exhibited acid‐triggered membranolytic function and potent peroxidase‐like (POD‐like) activity, which induce ferroptosis to tumor cells and inhibits tumor growth. The study suggests that this novel ML‐assisted design approach can offer an accurate and efficient paradigm for developing both oncolytic peptides and synergistic peptides for catalytic materials.
Industrial Waste Derived Separators for Zn‐Ion Batteries Achieve Homogeneous Zn(002) Deposition Through Low Chemical Affinity Effects
Authors: Yang Chengwu , Woottapanit Pattaraporn , Yue Yilei , Geng Sining , Cao Jin , Zhang Xinyu , He Guanjie , Qin Jiaqian 
Published: January 2024

AbstractDesigning a cost‐effective and multifunctional separator that ensures dendrite‐free and stable Zn metal anode remains a significant challenge. Herein, a multifunctional cellulose‐based separator is presented consisting of industrial waste‐fly ash particles and cellulose nanofiber using a facile solution‐coating method. The resulting fly ash‐cellulose (FACNF) separators enable a high ion conductivity (5.76 mS cm−1) and low desolvation energy barrier of hydrated Zn2+. These features facilitate fast ion transfer kinetics and inhibit water‐induced side reactions. Furthermore, experimental results and theoretical simulations confirm that the presence of fly ash particles in FACNF separators effectively accommodate the preferential deposition of Zn(002) planes, due to the weak chemical affinity between Zn(002) plane and fly ash, to mitigate dendrite formation and growth. Consequently, the utilization of FACNF separators causes an impressive cycling performance in both Zn||Zn symmetric cells (1600 h at 2 mA cm−2/1 mAh cm−2) and Zn||(NH4)2V10O25 (NVO) full cells (4000 cycles with the capacity retention of 92.1% at 5 A g−1). Furthermore, the assembled pouch cells can steadily support digital thermometer over two months without generating gas and volume expansion. This work provides new insights for achieving crystallographic uniformity in Zn anodes and realizing cost‐effective and long‐lasting aqueous zinc‐ion batteries (AZIBs).
Cobalt Nitride Nanoparticles Encapsulated in N‐Doped Carbon Nanotubes Modified Separator of Li–S Battery Achieving the Synergistic Effect of Restriction‐Adsorption‐Catalysis of Polysulfides
Authors: Jia Henan , Fan Jiahang , Su Pei , Guo Taotao , Liu Mao‐Cheng 
Published: January 2024

AbstractAlthough lithium–sulfur (Li–S) batteries have broad market prospects due to their high theoretical energy density and potential cost‐effectiveness, the practical applications still face serious shuttle effects of polysulfides (LiPSs) and slow redox reactions. Therefore, in this paper, cobalt nitride nanoparticles encapsulated in nitrogen‐doped carbon nanotube (CoN@NCNT) are prepared as a functional layer for the separator of high‐performance Li–S batteries. Carbon nanotubes with large specific surface areas not only promote the transport of ions and electrons but also weaken the migration of LiPSs and confine the dissolution of LiPSs in electrolytes. The lithiophilic heteroatom N adsorbs LiPSs by strong chemical adsorption, and the CoN particles with high catalytic activity greatly improve the kinetics of the conversion between LiPSs and Li2S2/Li2S during the charge–discharge process. Due to these advantages, the battery with CoN@NCNT modified separator has superior rate performance (initial discharge capacity of 834.7 mAh g−1 after activation at 1 C) and excellent cycle performance (capacity remains 729.7 mAh g−1 after 200 cycles at 0.2 C). This work proposes a strategy that can give the separator a strong ability to confinement‐adsorption‐catalysis of LiPSs in order to provide more possibilities for the development of Li–S batteries.
Exceptional Optical Anisotropy Enhancement Achieved Through Dual‐Ions Cosubstitution Strategy in Novel Hybrid Bismuth Halides
Authors: Bai Zhiyong , Ok Kang Min 
Published: January 2024

AbstractGuided by a superb dual‐ions cosubstitution strategy, two novel, highly optically anisotropic hybrid bismuth halides are designed and synthesized. The first compound, Gu3Bi2NO3Cl8 (Gu = C(NH2)3), is developed using the 2D perovskite halide Cs3Bi2Cl9 as the maternal structure. This involved substituting all Cs+ cations with organic Gu+ and replacing some Cl− anions with [NO3]−. Further substitution of Cl− with additional [NO3]− resulted in the formation of nitrate‐rich Gu2Bi(NO3)3Cl2 crystal, exhibiting a 3.4‐fold increase in [NO3]− per unit volume. Both compounds have a structurally 0D nature, comprising bismuth‐centered polyhedra formed by coordinated chlorides and monodentate/bidentate nitrate moieties, with Gu+ serving as a separator and linker. Notably, the presence of superb optically anisotropic dual‐ions, i.e., planar Gu+ and [NO3]−, enables these crystals to possess sharply enhanced optical anisotropy, with birefringence values more than 1 order of magnitude higher than that of the initial crystal Cs3Bi2Cl9 (0.162/0.186vs 0.011 at 546 nm). The discovery and characterization of Gu3Bi2NO3Cl8 and Gu2Bi(NO3)3Cl2 crystals provide new insights into achieving expected modifications in optical properties through the utilization of a dual‐ions cosubstitution strategy.