bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unilateral hippocampal sparing during whole brain radiotherapy for multiple brain metastases: narrative and critical review
Authors: Pospisil Petr , Hynkova Ludmila , Hnidakova Lucie , Maistryszinova Jana , Slampa Pavel , Kazda Tomas 
Published: January 2024

BackgroundThe landscape of brain metastases radiotherapy is evolving, with a shift away from whole-brain radiotherapy (WBRT) toward targeted stereotactic approaches aimed at preserving neurocognitive functions and maintaining overall quality of life. For patients with multiple metastases, especially in cases where targeted radiotherapy is no longer feasible due to widespread dissemination, the concept of hippocampal sparing radiotherapy (HA_WBRT) gains prominence.MethodsIn this narrative review we explore the role of the hippocampi in memory formation and the implications of their postradiotherapy lateral damage. We also consider the potential advantages of selectively sparing one hippocampus during whole-brain radiotherapy (WBRT). Additionally, by systematic evaluation of relevant papers published on PubMed database over last 20 years, we provide a comprehensive overview of the various changes that can occur in the left or right hippocampus as a consequence of radiotherapy.ResultsWhile it is important to note that various neurocognitive functions are interconnected throughout the brain, we can discern certain specialized roles of the hippocampi. The left hippocampus appears to play a predominant role in verbal memory, whereas the right hippocampus is associated more with visuospatial memory. Additionally, the anterior part of the hippocampus is more involved in episodic memory and emotional processing, while the posterior part is primarily responsible for spatial memory and pattern separation. Notably, a substantial body of evidence demonstrates a significant correlation between post-radiotherapy changes in the left hippocampus and subsequent cognitive decline in patients.ConclusionIn the context of individualized palliative radiotherapy, sparing the unilateral (specifically, the left, which is dominant in most individuals) hippocampus could expand the repertoire of strategies available for adapted WBRT in cases involving multiple brain metastases where stereotactic radiotherapy is not a viable option. Prospective ongoing studies assessing various memory-sparing radiotherapy techniques will define new standard of radiotherapy care of patients with multiple brain metastases.
Case report: Unilateral paralysis of the hypoglossal nerve as the only clinical sign of clivus meningioma - a case report and literature review
Authors: Stamenović Jelena , Živadinović Biljana , Đurić Vanja 
Published: January 2024

IntroductionClivus meningiomas are benign tumors that occur at the skull base in the posterior cranial fossa. Symptoms usually progress several months or years before diagnosis and may include: headache, vertigo, hearing impairment, ataxia with gait disturbances, sensory problems. In the neurological findings, paralysis of the lower cranial nerves is most often seen, which in the later course can be accompanied by cerebellar and pyramidal signs until the development of a consciousness impairment.Case presentationWe presented the case of a patient who at the time of diagnosis had only unilateral hypoglossal nerve paralysis with dysarthria and mild dysphagia. After the neurosurgical procedure, pathohistological analysis confirmed meningothelial meningioma.ConclusionEarly recognition of clivus tumors, which include meningiomas, is necessary in order to implement an adequate therapeutic procedure and prevent further deterioration of the patient’s condition.
Evolution of local computing time in parallel modeling of mobile networks
Authors: Zhukova L. F. , Shchur L. N. 
Published: January 2024

Introduction: The study concerns the properties of a parallel discrete-event simulation (PDES) model, namely a simple mobile network model known as a personal communication service (PCS) model. In this type of parallel computing, each process has its own computation time, known as local virtual time. The local virtual times change during the simulation process, forming a complex profile similar to the surface growth profile in physics.Methods: We apply the scaling theory of statistical physics to study the properties of the PCS model. We construct a simple local virtual time evolution algorithm for the PCS model and compare this theoretical time evolution model to a standard parallel mobile network implementation in Rensselaer’s Optimistic Simulation System (ROSS).Results: We show that the value of the critical exponent for the mobile network system is close to the value in the theoretical local virtual time profile model. A roughening transition is found in the LVT–PCS model, which belongs to the universality class of directed percolation in dimension 2 + 1.Discussion: We believe that the analogies we found can be useful for preliminary analyses of scalability, process desynchronization, and possible deadlocks in a wide class of parallel discrete-event simulation models.
Traditional activities and general and mental health of adult Indigenous peoples living off-reserve in Canada
Authors: Kassem Hallah , Harris M. Anne , Edwards-Wheesk Ruby , Liberda Eric N. 
Published: January 2024

IntroductionWe examined associations between traditional Indigenous activities and self-perceived general and mental health in adult Indigenous persons living off-reserve in Canada using the 2012 and 2017 Aboriginal Peoples Surveys (APS), the two most recent datasets. We utilized four traditional Indigenous activities including hunting, making clothes or footwear, making arts or crafts, and gathering wild plants to investigate these self-reported data.MethodsData from 9,430 and 12,598 respondents from the 2012 and 2017 APS, respectively, who responded to 15 questions concerning traditional activities were assessed using multivariable logistic regression to produce odds ratios (OR) and 95% confidence intervals (CI). Covariates included age, sex, education-level, income-level, Indigenous identity, residential school connection, ability to speak an Indigenous language, smoking status, and alcohol consumption frequency.ResultsUsing the 2012 APS, clothes-making was associated with poor self-reported general (OR = 1.50, 95%CI: 1.12–1.99) and mental (OR = 1.59, 95%CI: 1.14–2.21) health. Hunting was associated with good mental health (OR = 0.71 95%CI: 0.56–0.93). Similarly, 2017 analyses found clothes-making associated with poor general health (OR = 1.25, 95%CI: 1.01–1.54), and hunting associated with good general (OR = 0.76, 95%CI: 0.64–0.89) and mental (OR = 0.69, 95%CI: 0.58–0.81) health. Artmaking was associated with poor general (OR = 1.37, 95%CI: 1.17–1.60) and mental (OR = 1.85, 95%CI: 1.58–2.17) health.ConclusionHunting had protective relationships with mental and general health, which may reflect benefits of participation or engagement of healthier individuals in this activity. Clothes-making and artmaking were associated with poor general and poor mental health, possibly representing reverse causation as these activities are often undertaken therapeutically. These findings have implications for future research, programs and policies concerning Indigenous health.
Survival of bronchopulmonary cancers according to radon exposure
Authors: Dessemon Juliette , Perol Olivia , Chauvel Cécile , Noelle Hugo , Coudon Thomas , Grassot Lény , Foray Nicolas , Belladame Elodie , Fayette Jérôme , Fournie Françoise , Swalduz Aurélie , Neidhart Eve-Marie , Saintigny Pierre , Tabutin Mayeul , Boussageon Maxime , Gomez Frédéric , Avrillon Virginie , Perol Maurice , Charbotel Barbara , Fervers Béatrice 
Published: January 2024

IntroductionResidential exposure is estimated to be responsible for nearly 10% of lung cancers in 2015 in France, making it the second leading cause, after tobacco. The Auvergne-Rhône-Alpes region, in the southwest of France, is particularly affected by this exposure as 30% of the population lives in areas with medium or high radon potential. This study aimed to investigate the impact of radon exposure on the survival of lung cancer patients.MethodsIn this single-center study, patients with a histologically confirmed diagnosis of lung cancer, and newly managed, were prospectively included between 2014 and 2020. Univariate and multivariate survival analyses were carried out using a non-proportional risk survival model to consider variations in risk over time.ResultsA total of 1,477 patients were included in the analysis. In the multivariate analysis and after adjustment for covariates, radon exposure was not statistically associated with survival of bronchopulmonary cancers (HR = 0.82 [0.54–1.23], HR = 0.92 [0.72–1.18], HR = 0.95 [0.76–1.19] at 1, 3, and 5 years, respectively, for patients residing in category 2 municipalities; HR = 0.87 [0.66–1.16], HR = 0.92 [0.76–1.10], and HR = 0.89 [0.75–1.06] at 1, 3, and 5 years, respectively, for patients residing in category 3 municipalities).DiscussionAlthough radon exposure is known to increase the risk of lung cancer, in the present study, no significant association was found between radon exposure and survival of bronchopulmonary cancers.
Association between alcohol consumption and latent fasting blood glucose trajectories among midlife women
Authors: Wang Xingzhou , Lin Song , Wang Xiwei , Gao Pengxia , Chen Juan 
Published: January 2024

BackgroundThis investigation sought to elucidate the correlations between alcohol intake and trajectories of fasting blood glucose (FBG) among American women in midlife.MethodsOur analysis was rooted in the foundational data from the Study of Women’s Health Across the Nation (SWAN), a comprehensive longitudinal study centered on US women during their midlife transition. We employed group-based trajectory modeling to chart the FBG trajectories spanning from 1996 to 2005. Employing logistic regression, we gauged the odds ratios (ORs) and 95% confidence intervals (CIs) to draw connections between initial alcohol consumption and FBG trajectory patterns, whilst controlling for predominant potential confounders.ResultsOur cohort comprised 2,578 women in midlife, ranging in age from 42 to 52, each having a minimum of three subsequent FPG assessments. We discerned two distinct FBG trajectories: a low-stable pattern (n = 2,467) and a high-decreasing pattern (n = 111). Contrasted with the low-stable group, our data showcased an inverse relationship between alcohol intake and the high-decreasing FBG trajectory in the fully adjusted model 3. The most pronounced reduction was evident in the highest tertile of daily servings of alcoholic beverages (OR: 0.23, 95% CI: 0.10–0.52, p &lt; 0.001), percentage of kilocalories sourced from alcoholic beverages (OR: 0.30, 95% CI: 0.16–0.58, p &lt; 0.001), and daily caloric intake from alcoholic beverages (OR: 0.31, 95% CI: 0.16–0.62, p &lt; 0.001).ConclusionModerate alcohol consumption may protect against high FPG trajectories in middle-aged women in a dose–response manner. Further researches are needed to investigate this causality in midlife women.
Exploring the link between perceived physical literacy and academic performance outcomes: insights from the EHDLA study
Authors: Domínguez-Martín Gabriel , Tárraga-López Pedro J. , López-Gil José Francisco 
Published: January 2024

ObjectiveThe aim of this study was to verify the relationship between perceived physical literacy (PPL) and academic performance outcomes among Spanish adolescents aged 12–17 years.MethodsThis cross-sectional study is a secondary examination utilizing data derived from the Eating Healthy and Daily Life Activities (EHDLA) project. The Spanish Perceived Physical Literacy Instrument for Adolescents (S-PPLI) was used to evaluate the PPL of the participants. To determine academic performance, the numerical grades for each subject were added together and then divided by the total number of subjects.ResultsOverall, a positive trend in the association between S-PPLI scores and academic performance was observed. We identified two significant ranges within the S-PPLI scores. First, there was a significant range between 9 and 33 points on the S-PPLI, indicating an inverse association with academic performance. Second, another significant range was observed at scores of 34 points or higher on the S-PPLI, suggesting a positive association with academic performance. Participants with low PPL had the lowest academic performance (mean = 6.4; bias-corrected and accelerated (BCa) bootstrapped 95% confidence interval (CI): 6.2–6.6). Conversely, those adolescents with high PPL had the highest academic performance (mean = 6.9; BCa bootstrapped 95% CI: 6.6–7.1). Significant differences were found between low PPL and medium PPL (p-adjusted = 0.031) and between low PPL and high PPL (p-adjusted = 0.031).ConclusionsIncreased physical literacy could be a relevant factor for achieving greater academic performance in adolescents. This study has potential implications for physical education instructors, school leaders, and healthcare practitioners.
Hot spots and frontiers in bone-tendon interface research: a bibliometric analysis and visualization from 2000 to 2023
Authors: Xiao Hao , Wen Boyuan , Yan Dong , Li Quansi , Yang Yujie , Yin Xianye , Chen Deyu , Liu Jiachen 
Published: January 2024

ObjectiveIn this research, we investigated the current status, hotspots, frontiers, and trends of research in the field of bone-tendon interface (BTI) from 2000 to 2023, based on bibliometrics and visualization and analysis in CiteSpace, VOSviewer, and a bibliometric package in R software.MethodsWe collected and organized the papers in the Web of Science core collection (WoSCC) for the past 23 years (2000–2023), and extracted and analyzed the papers related to BTI. The extracted papers were bibliometrically analyzed using CiteSpace for overall publication trends, authors, countries/regions, journals, keywords, research hotspots, and frontiers.ResultsA total of 1,995 papers met the inclusion criteria. The number of papers published and the number of citations in the field of BTI have continued to grow steadily over the past 23 years. In terms of research contribution, the United States leads in terms of the number and quality of publications, number of citations, and collaborations with other countries, while the United Kingdom and the Netherlands lead in terms of the average number of citations. The University of Leeds publishes the largest number of papers, and among the institutions hosting the 100 most cited papers Hospital for Special Surgery takes the top spot. MCGONAGLE D has published the highest number of papers (73) in the last 10 years. The top three clusters include #0 “psoriatic arthritis”, #1 “rotator cuff repair”, and #2 “tissue engineering”. The structure and function of the BTI and its key mechanisms in the healing process are the key to research, while new therapies such as mechanical stimulation, platelet-rich plasma, mesenchymal stem cells, and biological scaffolds are hot topics and trends in research.ConclusionOver the past 23 years, global research on the BTI has expanded in both breadth and depth. The focus of research has shifted from studies concentrating on the structure of the BTI and the disease itself to new therapies such as biomaterial-based alternative treatments, mechanical stimulation, platelet-rich plasma, etc.
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN ABORTUS TERHADAP IBU HAMIL DI RUMAH SAKIT UMUM DAERAH BENGKALIS
Authors: Alhidayati  , Syukaisih  , Amalia Risa , Arisha Popyana 
Published: January 2024

Abortion is the end of a pregnancy before the fetus is able to survive, namely when the gestational age has not reached 20 weeks or the fetus weighs <500 grams, either spontaneously or induced. Research objective to determine the relationship between age, education, profession, parity, knowledge, attitudes, family support and support from health workers on the incidence of abortion at the Bengkalis Regional General Hospital in 2023. This research is quantitative analytic with cross sectional research design. The population in this study were pregnant women who were treated at the Bengkalis regional general hospital from January to May, totaling 627 mothers. Simple random sampling

technique with a total sample of 96 respondents. Measuring tool in data collection is a questionnaire. Data analysis with univariate and bivariate with chi-square. Research results show that there is a significant relationship between age and the incidence of abortion (P value = 0.004) OR = 0.263, there is a significant relationship between parity and the incidence of abortion (P value = 0.021) OR = 0.331, there is a significant relationship between attitude and the incidence of abortion ( P value = 0.000) OR = 0.161, there is a significant relationship between family support and abortion (P value = 0.048) OR = 0.192, there is a significant relationship between health worker support and abortion (P value = 0.021) OR = 0.159, none there is a significant relationship between education and abortion (P value = 0.139), there is no significant relationship between profession and abortion (P value = 1.000), there is no significant relationship between knowledge and abortion (P value = 0.528). It is hoped that the results of this study can be an illustration for health services to improve the quality of health, especially dealing with abortion cases.
FAKTOR FAKTOR YANG MEMPENGARUHI KEJADIAN STUNTING PADA BALITA DI WILAYAH KERJA PUSKESMAS TAMBARUNTUNG
Authors: Misnawati  , Novalia Widiya Ningrum  , Zulfadhilah Muhammad , Hestiyana Nita 
Published: January 2024

Prevalensi balita stunting di Kalimantan Selatan 31,75% dan di Kabupaten Tapin sebesar 36,04% dan berada pada peringkat kelima tertinggi se-Kalimantan Selatan. Dengan adanya prevalensi tersebut maka dilakukan penelitian ini untuk mengetahui faktor-faktor yang mempengaruhi kejadian stunting pada balita di wilayah kerja Puskesmas Tambaruntung Kecamatan Tapin Tengah. Jenis penelitian observasional analitik dengan rancangan penelitian cross sectional. Dilaksanakan di wilayah kerja Puskesmas Tambaruntung dengan jumlah sampel sebanyak 89 anak balita dengan cara Simple Random Sampling, mengunakan uji Chi-Square. Responden penelitian ibu balita. Variabel independen penelitian adalah ASI Eksklusif, pengetahuan ibu, dan status gizi ibu. Adapun variabel dependen penelitian yaitu kejadian stunting. Kejadian stunting pada balita tahun 2023 adalah 35,95%, ASI Eksklusif 55,1%, berpengetahuan baik sebesar 57,30% dan ibu balita dengan KEK 46,1%.
Uji analisis statistik Crosstabulation Chi-Square p=0,000 dapat disimpulkan bahwa ada Pengaruh antara pemberian ASI Eksklusif, pengetahuan ibu, dan status gizi ibu dan dengan kejadian stunting di wilayah kerja Puskesmas Tambaruntung Kecamatan Tapin Tengah
HUBUNGAN LINGKAR LENGAN ATAS (LILA) DENGAN KADAR HEMOGLOBIN PADA IBU BERSALIN
Authors: Fitri Imelda , Badriyah Nurul , Dewi Anita Sari Citra 
Published: January 2024

Prevelensi anemia meningkat dua tahun terakhir. Tujuan Penelitian ini mengetahui hubungan limgkar lengan atas (LILA) dengan kadar hemoglobin (Hb) pada ibu bersalin. Desain penelitian ini Cross Sectional. Sampel penelitian ini ibu bersalin berjumlah 43 responden, teknik pengambilan sampelnya menggunakan total sampling. Penelitian ini dilaksanakan di Praktek Mandiri Bidan Rosita Pekanbaru, instrumen penelitian adalah pita ukur LILA dan easy touch untuk mengukur kadar Hb . Data dianalisis dengan uji Chi Square dengan signifikan p<0,5. Hasil penelitian menunjukkan ibu bersalin dengan LILA kurang (< 23,5 cm) memiliki 5 kali (OR=5,11, 95% CI : 1,28-20,49) lebih besar kemungkinan mengalami anemia dari pada ibu bersalin yang LILA normal, ada hubungan lingkar lengan atas dengan kadar hemoglobin ibu bersalin dengan (p < 0,05). Lingkar lengan atas yang merupakan indikator status gizi ibu bersalin, jika dibawah standar (< 23,5) beresiko untuk anemia.
IMPLEMENTASI ALGORITMA K-MEANS UNTUK SEGMENTASI PELANGGAN PADA PT. BINTANG MULTI SARANA CABANG TUGUMULYO
Authors: Mawarni Herlinda , Testiana Gusmelia , Dalafranka Muhammad Leandry 
Published: January 2024

Salah satu aset terpenting perusahaan adalah pelanggannya. Berbagai cara dilakukan oleh perusahaan untuk mempertahankan pelanggan dengan menerapkan berbagai startegi seperti pada PT Bintang Multi Sarana yang melakukan berbagai macam cara untuk menjalin hubungan baik dengan pelanggan seperti mengadakan promo dan diskon. Perusahaan menawarkan barang promo atau diskon dengan cara menghubungi pelanggan melalui telepon satu per satu atau menawarkan secara langsung ketika pelanggan selesai membeli barang sebelumnya. Penawaran diskon dan promo keseluruh pelanggan ini kurang efisien karena memakan banyak biaya untuk operasioanl dan menyita banyak waktu. Oleh sebab itu, pelanggan yang ada di PT Bintang Multi Sarana perlu dikelompokan terlebih dahulu agar dapat mempermudah perusahaan dalam menentukan layanan yang sesuai. Selain itu data transaksi penjualan pada PT Bintang Multi Sarana hanya diolah menjadi laporan bulanan saja. Padahal jika diolah dengan tepat, data transaksi penjualan dapat digunakan untuk membantu menentukan strategi dalam mempertahankan pelanggan. Tujuan penelitian ini yaitu melakukan segmentasi pelanggan untuk mengetahui karakteristik pelanggan. Salah satu solusi untuk permasalahan tersebut yaitu dengan mengolah data transaksi penjualan dengan memanfaatkan peran dari data mining dengan teknik clustering menggunakan algoritma k-means. Algoritma k-means merupakan algoritma berbasis jarak yang membagi data kedalam cluster terpisah. Berdasarkan perhitungan menggunakan k-means, pelanggan tercluster kedalam 3 kelompok yaitu cluster 1 sebanyak 742 pelanggan, cluster 2 sebanyak 795 pelanggan dan cluster 3 sebanyak 223 pelanggan. Dari hasil analisis segmentasi pelanggan diperoleh hasil bahwa cluster 1 merupakan pelanggan segmen silver, cluster 2 pelanggan segmen gold, dan cluster 3 pelanggan segmen platinum. Adapun strategi pemasaran untuk segmen silver dengan pemberian diskon harga, promosi dan iklan di media sosial, untuk segmen gold diberikan layanan berupa point reward atau diskon khusus, sedangkan untuk segmen platinum yaitu pemberian hadiah menarik, atau akses eksklusif terhadap produk tertentu.
Peran Pemeriksaan Ultrasonografi dalam Diagnosa Klinis Flexor Tenosynovitis Piogenik
Authors: Supartono Basuki , Dohong Almerveldy Azaria , Widiyani Khadijah Ratna , Nadia Nadia 
Published: January 2024

Pyogenic Flexor Tenosynovitis (PFT) adalah infeksi pada selubung tendon fleksor tangan. Diagnosis PFT dapat ditegakkan secara klinis apabila terdapat empat tanda kardinal Kanavel. Namun, jika tidak terdapat empat tanda tersebut, maka dianjurkan pemeriksaan penunjang berupa ultrasonografi tangan. Pada salah satu penelitian didapatkan ultrasonografi (USG) memiliki sensitivitas 94%, spesifisitas 74% dan nilai prediksi negatif 97% dalam menentukan diagnosis PFT. Penelitian ini bertujuan untuk menganlisis peran ultrasonografi berperan dalam membantu penegakkan diagnosa PFT disertai dengan penelitian-penelitian yang mendukung pernyataan tersebut. Metode penelitian yang dapat digunakan untuk mengkaji kasus Pyogenic Flexor Tenosynovitis (PFT) adalah studi kasus. Penelitian yang secara khusus mendukung peran USG sebagai pemeriksaan penunjang yang tepat untuk PFT masih sangat sedikit, sedangkan penanganan yang cepat dan tepat diperlukan untuk mendapatkan prognosis yang baik. Oleh karena itu perlu dibahas bagaimana USG memiliki peran dalam membantu diagnosa dari PFT. Hasil ditemukan memiliki sensitivitas 94%, spesifisitas 74% dan nilai prediksi negatif 97% dalam menentukan diagnosis PFT, dan pada penelitian juga menunjukkan kisaran sensitifias 94% dalam mendeteksi abnormalitas tendon di tangan serta jari-jarinya, temuan ini membantu ahli bedah menentukan pengobatan yang tepat.