bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative study on wound healing and infection between open and minimally invasive surgical methods in pediatric otolaryngology surgery
Authors: Wu Xionghui , Huang Weiqing , Zhao Sijun , Huang Min , Kuang Yuting , Liu Guangliang 
Published: February 2024

AbstractPediatric otolaryngology surgeries are crucial interventions requiring careful consideration of surgical methods to optimize outcomes. The choice between open and minimally invasive surgical approaches in this context warrants thorough investigation. While both methods aim to address ear, nose, and throat conditions in children, a comparative study assessing their impact on crucial factors such as intraoperative parameters, wound healing, complications, and postoperative pain is essential. This study aims to compare the effects of open and minimally invasive surgical methods on wound healing and infection in pediatric otolaryngology surgery, and provide a scientific basis for the selection of surgical methods. Two groups of patients were selected, with 90 people in each group. One group received open surgery and the other received minimally invasive surgery. Recording the intraoperative time, anesthesia time, and intraoperative blood loss; the number of days required for wound healing; the occurrence of wound‐related complications; the comparison of pain on postoperative Days 1, 3, and 7; and the factors influencing postoperative wound healing were analyzed. In the minimally invasive surgery group, the intraoperative time was shorter, the anesthesia time was relatively reduced, and the amount of bleeding was significantly reduced. Wounds also take fewer days to heal and have lower rates of wound‐related complications. When comparing the pain on 1, 3, and 7 days after surgery, the minimally invasive surgery group had relatively mild pain. Analysis of postoperative wound healing factors showed that minimally invasive surgical methods have a positive impact on healing. In pediatric otolaryngology surgery, minimally invasive surgery performs better than open surgery in terms of intraoperative operation time, anesthesia time, blood loss, wound healing time, complication rate, and postoperative pain. Therefore, minimally invasive surgery may be a safer and more effective surgical method.
Role of hydrocolloid dressing in preventing face pressure ulcers from non‐invasive ventilation and facilitating postoperative wound healing in maxillofacial surgery: A meta‐analysis
Authors: Wang Jingqi , Gao Qian , Feng Xiaolan , Chen Yi 
Published: February 2024

AbstractFacial pressure ulcers from non‐invasive ventilation (NIV) and challenges in wound healing post‐maxillofacial surgery are significant concerns in clinical care. This meta‐analysis aimed to evaluate the effectiveness of hydrocolloid dressings in these contexts. From a pool of 1135 articles, 8 studies met the inclusion criteria. Hydrocolloid dressings demonstrated a significant reduction in facial pressure ulcers for NIV patients, with lower REEDA scores 1‐week postapplication (standardized mean difference [SMD] = −16.7, 95% confidence interval [CI]: −24.26 to −9.15, p < 0.01). In maxillofacial surgery, patients treated with hydrocolloid dressings exhibited improved wound healing and reduced scar formation, evidenced by lower Manchester Scar Scale scores 3 months post‐surgery (SMD = −15.46, 95% CI: −20.28 to −10.64, p < 0.01). These findings suggest that hydrocolloid dressings are effective in both preventing NIV‐related facial pressure ulcers and enhancing wound healing in maxillofacial surgery.
Predictors of mental health in healthcare workers during the COVID‐19 pandemic: The role of experiential avoidance, emotion regulation and resilience
Authors: Rodríguez‐Rey Rocío , Guerra Corral Marta , Collazo‐Castiñeira Paula , Collado Silvia , Caro‐Carretero Raquel , Cantizano Alexis , Garrido‐Hernansaiz Helena 
Published: February 2024

AbstractAimsThis study explores the mediational role of resilience, experiential avoidance and emotion regulation in the levels of anxiety, depression and posttraumatic stress disorder (PTSD) of healthcare workers during the COVID‐19 pandemic. Additionally, we explored the association of such levels with personal and professional variables.DesignCross‐sectional study.MethodsHealthcare professionals working in Spain (N = 786) were recruited following a snowball approach in November and December 2021. Resilience, emotion regulation, experiential avoidance, depression, anxiety, PTSD and work‐related variables were measured. Mean differences and correlations were computed, and a path analysis with latent variables (PALV) model was tested.ResultsIn total, 18.8% of the sample scored above the cut‐off score for depression, 24.6% for anxiety and 36.4% for PTSD. Higher resilience and lower experiential avoidance and expression suppression were correlated with better mental health. The PALV model explained 42%–53% of mental health outcomes. Experiential avoidance showed the greatest explanatory power and mediated the impact that stressors had on mental health. Some work‐related variables correlated with greater psychological impact. These factors encompassed being a nurse, feeling that their job remained stressful and had not yet returned to its pre‐pandemic state and having interacted with individuals facing economic difficulties due to the pandemic, and those who had lost their lives to COVID‐19.ConclusionHealthcare workers showed high levels of psychological impact during the COVID‐19 pandemic. Such impact was predicted from some work‐stress variables and the reliance on maladaptive strategies such as experiential avoidance and expressive suppression.ImpactTraining healthcare professionals to use coping strategies incompatible with experiential avoidance may improve their mental health. Additionally, better working conditions are fundamental for reducing the impact of critical situations on healthcare workers' mental health.Patient or Public ContributionNo patient or public contribution.
ACES: A new framework for the application of the 2018 periodontal status classification scheme to epidemiological survey data
Authors: Holtfreter Birte , Kuhr Kathrin , Borof Katrin , Tonetti Maurizio S. , Sanz Mariano , Kornman Kenneth , Jepsen Søren , Aarabi Ghazal , Völzke Henry , Kocher Thomas , Krois Joachim , Papapanou Panos N. 
Published: February 2024

AbstractAimTo propose a framework for consistently applying the 2018 periodontal status classification scheme to epidemiological surveys (Application of the 2018 periodontal status Classification to Epidemiological Survey data, ACES).Proposed FrameworkWe specified data requirements and workflows for either completed or planned epidemiological surveys, utilizing commonly collected measures of periodontal status (clinical attachment levels [CAL], probing depths, bleeding on probing), as well as additional necessary variables for the implementation of the 2018 periodontal status classification (tooth loss due to periodontitis and complexity factors). Following detailed instructions and flowcharts, survey participants are classified as having periodontal health, gingivitis or periodontitis. Rates of edentulism must also be reported. In cases of periodontitis, instructions on how to compute the stage and extent are provided. Assessment of grade can be derived from CAL measurements (or from radiographic alveolar bone loss data) in relation to root length and the participant's age.ConclusionsACES is a framework to be used in epidemiological studies of periodontal status that (i) have been completed, and in which stage and grade according to the 2018 classification are inferred retroactively, or (ii) are being planned. Consistent use of the proposed comprehensive approach will facilitate the comparability of periodontitis prevalence estimates across studies.
Effect of hot air circulation roasting temperature on the sensory property and odor characteristics of cashew nut (Anacardium occidentale L.)
Authors: Chen Haoshuang , He Shudong , Pei Hui , Gao Kuan , Gao Lingyan , Cao Xiaodong , Sun Hanju , Song Jiazhen 
Published: February 2024

AbstractEffects of hot air circulation roasting temperature on cashew nut sensory and aroma profiles were assessed in this study. Optimal roasting at 130°C for 20 min yielded a uniform, glossy appearance and rapid water loss. Sensory and electronic nose (E‐nose) analyses indicated enhanced sweet, milky, and fatty aromas. Gas chromatography–mass spectrometry identified more than 180 volatile compounds. Roasting at 150°C for 20 min produced a burnt aroma, with a decrease in alkenes and aromatic hydrocarbons and an increase in alkanes, acids, ketones, and pyrazines. Principal component analysis distinguished between 130 and 150°C roasting samples, and key volatile compounds included phenylethanol, 1‐octen‐3‐ol, naphthalene, (−)‐alpha pinene, trans caryophyllene, 2,5‐dimethylpyrazine, 2‐methylbutyr‐aldehyde, heptaldehyde, 2,3,5‐trimethylpyrazine, and n‐octanol. Compared to traditional roasting, hot air circulation roasting offers efficiency, convenience, energy savings, and environmental benefits.Practical applicationsCashew nuts are esteemed as a nutritious treat mainly due to their profound taste and elevated nutrient content. This research explored the influence of applying hot air circulation during the roasting procedure on various aspects of physical and chemical properties, flavor, and energy consumption. By establishing a systematic theoretical model of the process, this work can effectively manipulate the roasting parameters to attain an optimal flavor profile desirable for cashew nuts. Moreover, the efficiency of this novel approach outperforms conventional techniques, offering substantial energy cost savings, and showcasing its virtues of high efficacy, eco‐friendliness, and environmental preservation. The investigation revealed that utilizing hot air circulation leads to cashew nuts possessing a superior gustatory sensation and nutritional profile. Therefore, it can safely be stated that hot air circulation roasting could serve as an exemplary methodology for household nut manufacturing, thereby warranting further consideration of this innovative technique in private nut production.
Cell density impacts the susceptibility to ferroptosis by modulating IRP1‐mediated iron homeostasis
Authors: Yan Hong‐fa , Tuo Qing‐zhang , Lei Peng 
Published: February 2024

AbstractFerroptosis has been implicated in several neurological disorders and may be therapeutically targeted. However, the susceptibility to ferroptosis varies in different cells, and inconsistent results have been reported even using the same cell line. Understanding the effects of key variables of in vitro studies on ferroptosis susceptibility is of critical importance to facilitate drug discoveries targeting ferroptosis. Here, we showed that increased cell seeding density leads to enhanced resistance to ferroptosis by reducing intracellular iron levels. We further identified iron‐responsive protein 1 (IRP1) as the key protein affected by cell density, which affects the expression of ferroportin or transferrin receptor and results in altered iron levels. Such observations were consistent across different cell lines, indicating that cell density should be tightly controlled in studies of ferroptosis. Since cell densities vary in different brain regions, these results may also shed light on selective regional vulnerability observed in neurological disorders.image
A Group Randomized Controlled Trial of Relationships Under Construction Sexual Risk Avoidance Education
Authors: Ashley Olivia , Shamblen Stephen R. , Gluck Andrew , Wood Catherine 
Published: February 2024

ABSTRACTBACKGROUNDWe analyzed data from a study to evaluate the effectiveness of the Relationships Under Construction (RUC) sexual risk avoidance education program promoting positive youth development and healthy relationships.METHODSTwelve schools in the Midwestern region of the United States randomized to the intervention implemented RUC in health or science classes, while control schools collected study measures and implemented the standard curriculum.RESULTSPost‐randomization analyses revealed significant differences in grade, race/ethnicity, and prior relationship education at baseline between intervention and control students. Subsequent analyses controlled for these differences. We distributed parental notification letters to 641 students, and no parents requested that their adolescent opt out of data collection. We obtained assent and baseline computer‐assisted survey interviews or paper‐and‐pencil instrument forms from 100% of these students. Findings suggest that RUC significantly reduced sexual activity (odds ratio = 0.56, p = .046) at 3‐month follow‐up, compared to those in the control group. RUC also reduced pornography viewing and improved attitudes about delayed gratification, beliefs, decision making, and negative outcome expectations.CONCLUSIONSOur findings suggest that RUC improves sexual attitudes, beliefs, and behaviors among this population of adolescents. Additional research is needed to assess RUC impacts among diverse populations.
Speciation across biomes: Rapid diversification with reproductive isolation in the Australian delicate mice
Authors: Roycroft Emily , Ford Fred , Ramm Till , Schembri Rhiannon , Breed William G. , Burns Phoebe A. , Rowe Kevin C. , Moritz Craig 
Published: February 2024

AbstractPhylogeographic studies of continental clades, especially when combined with palaeoclimate modelling, provide powerful insight into how environment drives speciation across climatic contexts. Australia, a continent characterized by disparate modern biomes and dynamic climate change, provides diverse opportunity to reconstruct the impact of past and present environments on diversification. Here, we use genomic‐scale data (1310 exons and whole mitogenomes from 111 samples) to investigate Pleistocene diversification, cryptic diversity, and secondary contact in the Australian delicate mice (Hydromyini: Pseudomys), a recent radiation spanning almost all Australian environments. Across northern Australia, we find no evidence for introgression between cryptic lineages within Pseudomys delicatulus sensu lato, with palaeoclimate models supporting contraction and expansion of suitable habitat since the last glacial maximum. Despite multiple contact zones, we also find little evidence of introgression at a continental scale, with the exception of a potential hybrid zone in the mesic biome. In the arid zone, combined insights from genetic data and palaeomodels support a recent expansion in the arid specialist P. hermannsburgensis and contraction in the semi‐arid P. bolami. In the face of repeated secondary contact, differences in sperm morphology and chromosomal rearrangements are potential mechanisms that maintain species boundaries in these recently diverged species. Additionally, we describe the western delicate mouse as a new species and recommend taxonomic reinstatement of the eastern delicate mouse. Overall, we show that speciation in an evolutionarily young and widespread clade has been driven by environmental change, and potentially maintained by divergence in reproductive morphology and chromosome rearrangements.
The origin and speciation of orchids
Authors: Pérez‐Escobar Oscar A. , Bogarín Diego , Przelomska Natalia A. S. , Ackerman James D. , Balbuena Juan A. , Bellot Sidonie , Bühlmann Roland P. , Cabrera Betsaida , Cano Jose Aguilar , Charitonidou Martha , Chomicki Guillaume , Clements Mark A. , Cribb Phillip , Fernández Melania , Flanagan Nicola S. , Gravendeel Barbara , Hágsater Eric , Halley John M. , Hu Ai‐Qun , Jaramillo Carlos , Mauad Anna Victoria , Maurin Olivier , Müntz Robert , Leitch Ilia J. , Li Lan , Negrão Raquel , Oses Lizbeth , Phillips Charlotte , Rincon Milton , Salazar Gerardo A. , Simpson Lalita , Smidt Eric , Solano‐Gomez Rodolfo , Parra‐Sánchez Edicson , Tremblay Raymond L. , van den Berg Cassio , Tamayo Boris Stefan Villanueva , Zuluaga Alejandro , Zuntini Alexandre R. , Chase Mark W. , Fay Michael F. , Condamine Fabien L. , Forest Felix , Nargar Katharina , Renner Susanne S. , Baker William J. , Antonelli Alexandre 
Published: February 2024

Summary
Orchids constitute one of the most spectacular radiations of flowering plants. However, their origin, spread across the globe, and hotspots of speciation remain uncertain due to the lack of an up‐to‐date phylogeographic analysis.
We present a new Orchidaceae phylogeny based on combined high‐throughput and Sanger sequencing data, covering all five subfamilies, 17/22 tribes, 40/49 subtribes, 285/736 genera, and c. 7% (1921) of the 29 524 accepted species, and use it to infer geographic range evolution, diversity, and speciation patterns by adding curated geographical distributions from the World Checklist of Vascular Plants.
The orchids' most recent common ancestor is inferred to have lived in Late Cretaceous Laurasia. The modern range of Apostasioideae, which comprises two genera with 16 species from India to northern Australia, is interpreted as relictual, similar to that of numerous other groups that went extinct at higher latitudes following the global climate cooling during the Oligocene. Despite their ancient origin, modern orchid species diversity mainly originated over the last 5 Ma, with the highest speciation rates in Panama and Costa Rica.
These results alter our understanding of the geographic origin of orchids, previously proposed as Australian, and pinpoint Central America as a region of recent, explosive speciation.
Ocular surface changes following computer use in post‐LASIK patients
Authors: Talens‐Estarelles Cristian , Talens‐Estarelles Clara , García‐Lázaro Santiago 
Published: February 2024

AbstractPurposeTo assess the impact of computer use on the ocular surface of individuals after laser in situ keratomileusis (LASIK).MethodsThe dry eye symptoms and ocular surface of 18 post‐LASIK young individuals and 18 controls were evaluated before and after performing a 30‐min task on a computer without (Visit 1) and with (Visit 2) initial instillation of artificial tears. Symptoms were assessed using the Ocular Surface Disease Index (OSDI), Symptom Assessment in Dry Eye questionnaire version two (SANDE II) and Computer Vision Syndrome Questionnaire (CVS‐Q). The ocular surface was assessed by measuring corneal higher order aberrations, tear meniscus height (TMH), conjunctival redness, blink rate and incomplete blinking, lipid layer thickness (LLT) and non‐invasive keratograph break‐up time (NIKBUT).ResultsSANDE II scores were >0 after the computer task in both groups (p ≤ 0.01). SANDE II and CVS‐Q scores did not differ between LASIK and controls (p ≥ 0.43). Greater bulbar–temporal conjunctival redness, TMH and LLT and shorter NIKBUT were found after computer use in the LASIK group (p ≤ 0.04), whereas no changes were observed in the controls (p ≥ 0.20). Lower SANDE II and CVS‐Q scores were reported at Visit 2 compared with Visit 1 in both groups (p ≤ 0.01). Likewise, no worsening of dry eye signs was observed at Visit 2 (p ≥ 0.11).ConclusionsOcular symptoms reported during computer use were comparable between the groups. However, a worsening of dry eye signs was mostly observed in post‐LASIK individuals. The instillation of artificial tears was effective in preventing the effects of computer use on the ocular surface in post‐LASIK patients.
Expression of Toll‐like receptors and host defence peptides in the cecum of chicken challenged with Eimeria tenella
Authors: Wang Song , Wang Danni , Bai Yilin , Zheng Guijie , Han Yanhui , Wang Lei , Hu Jianhe , Zhu Huili , Bai Yueyu 
Published: February 2024

AbstractChicken coccidiosis, caused by Eimeria protozoa, affects poultry farming. Toll‐like receptors (TLRs) and host defence peptides (HDPs) help host innate immune responses to eliminate invading pathogens, but their roles in Eimeria tenella infection remain poorly understood. Herein, 14‐day‐old chickens were treated orally with 50,000 E. tenella oocysts and the cecum was dissected at different timepoints. mRNA expression of 10 chicken TLRs (chTLRs) and five HDPs was measured by quantitative real‐time PCR. chTLR7 and chTLR15 were upregulated significantly at 3 h post‐infection while other chTLRs were downregulated (p < .05). chTLR1a, chTLR1b, chTLR2b and chTLR4 peaked at 36 h post‐infection, chTLR3, chTLR5 and chTLR15 peaked at 72 h post‐infection and chTLR21 expression was highest among chTLRs, peaking at 48 h post‐infection (p < 0.05). For HDPs, cathelicidin (CATH) 1 to 3 and B1 peaked at 48 h post‐infection, liver‐expressed antimicrobial peptide 2 peaked at 96 h post‐infection, and CATH 2 expression was highest among HDPs. CATH2 and CATH3 were markedly upregulated at 3 h post‐infection (p < .05). The results provide insight into innate immune molecules during E. tenella infection in chicken, and indicate that innate immune responses may mediate resistance to chicken coccidiosis.
Multiomics analyses reveal the mechanisms of the responses of subalpine treeline trees to phenology and winter low‐temperature stress
Authors: Yu Dongyue , Zhang Yanjun , Dang Haishan , Zhang Quanfa 
Published: February 2024

AbstractWithstanding extreme cold stress is a prerequisite for alpine treeline trees to persist and survive. However, the underlying mechanism by which treeline trees sense phenological changes and survive hard winters has not been fully elucidated. Here, we investigated the physiology, transcriptome, and metabolome of the subalpine treeline species Larix chinensis to identify the molecular mechanism of phenological and cold resistance. Calcium and antioxidant enzyme activities (e.g., superoxide dismutase and glutathione peroxidase) are essential for coping with winter cold stress in L. chinensis. Transcriptome analysis revealed that circadian rhythm and phytohormone signalling transduction played important roles in regulating L. chinensis phenological changes and cold stress responses. The variations in the transcriptome identified were accompanied by the specific accumulation of flavones, flavonols, and monosaccharides. The flavonoid biosynthesis and phenylpropanoid biosynthesis pathways played important roles in the adaptation of L. chinensis to the extreme winter environment, and flavone and flavonol biosynthesis was an important pathway involved in bud burst. In addition, temperature and photoperiod had synergistic influences on the formation and release of bud dormancy. Thus, our findings provided new insights into the mechanism of subalpine treeline formation.
Phenomenology and cognitive linguistics in dialogue: A review of Ortega y Gasset's theory of emotive gesture as metaphor
Authors: Expósito Ropero Noé , Soares da Silva Augusto 
Published: February 2024

AbstractThe present study pursues three objectives. First, to expose and discuss the contributions of the philosopher José Ortega y Gasset to the phenomenological study of gestures and emotive gesture. Secondly, to critically review one of the central theses defended by Ortega, according to which “every expressive phenomenon”—including, therefore, the emotive gesture—involves “a transposition, that is to say, an essential metaphor.” This thesis invites us, in the third objective, to establish a dialogue between phenomenology and cognitive linguistics (as developed by Lakoff, Langacker and Talmy), assuming an experientialist position vis‐à‐vis human reason and language, in opposition to the objectivist and formalist position of Chomsky's generative linguistics. In this interdisciplinary context, we will study the phenomenon of emotive gesture, in particular the expression of the emotion of anger, as analyzed phenomenologically by Ortega y Gasset.