bluuebunny/crossref_metadata_2025_split huggingface dataset:
Longitudinal clustering of health behaviours and their association with multimorbidity in older adults in England: A latent class analysis
Authors: Suhag Alisha , Webb Thomas L. , Holmes John 
Published: January 2024

Background
Health-risk behaviours such as smoking, unhealthy nutrition, alcohol consumption, and physical inactivity (termed SNAP behaviours) are leading risk factors for multimorbidity and tend to cluster (i.e. occur in specific combinations within distinct subpopulations). However, little is known about how these clusters change with age in older adults, and whether and how cluster membership is associated with multimorbidity.

Methods
Repeated measures latent class analysis using data from Waves 4–8 of the English Longitudinal Study of Ageing (ELSA; n = 4759) identified clusters of respondents with common patterns of SNAP behaviours over time. Disease status (from Wave 9) was used to assess disorders of eight body systems, multimorbidity, and complex multimorbidity. Multinomial and binomial logistic regressions were used to examine how clusters were associated with socio-demographic characteristics and disease status.

Findings
Seven clusters were identified: Low-risk (13.4%), Low-risk yet inactive (16.8%), Low-risk yet heavy drinkers (11.4%), Abstainer yet inactive (20.0%), Poor diet and inactive (12.9%), Inactive, heavy drinkers (14.5%), and High-risk smokers (10.9%). There was little evidence that these clusters changed with age. People in the clusters characterised by physical inactivity (in combination with other risky behaviours) had lower levels of education and wealth. People in the heavy drinking clusters were predominantly male. Compared to other clusters, people in the Low-risk and Low-risk yet heavy drinkers had a lower prevalence of all health conditions studied. In contrast, the Abstainer but inactive cluster comprised mostly women and had the highest prevalence of multimorbidity, complex multimorbidity, and endocrine disorders. High-risk smokers were most likely to have respiratory disorders.

Conclusions
Health-risk behaviours tend to be stable as people age and so ought to be addressed early. We identified seven clusters of older adults with distinct patterns of behaviour, socio-demographic characteristics and multimorbidity prevalence. Intervention developers could use this information to identify high-risk subpopulations and tailor interventions to their behaviour patterns and socio-demographic profiles.
An Unusual Case of Gastric Heterotopia Presenting as Rectal Prolapse
Authors: D'Sa Saskia , Mziray-Andrew Charmaine , Porayette Prashanth 
Published: January 2024

ABSTRACTHeterotopic gastric mucosa (HGM) involving the rectum is an uncommon finding. It is especially rare in young children. Rectal prolapse is an uncommon presentation of HGM. We report a case of HGM in the rectum of a 2-year-old previously healthy girl, who presented with rectal prolapse and painless bleeding. Endoscopic mucosal resection was performed to completely resect the lesion after the patient failed to respond to proton pump inhibitors. This case underscores the importance of considering HGM involving the rectum as a cause of rectal prolapse in young pediatric patients.
Non-classical manifestation of multiple endocrine neoplasia type 1
Authors: Bibik E. E. , Aboishava L. A. , Matyushkina A. S. , Eremkina A. K. , Degtyarev M. V. , Platonova N. M. , Troshina E. A. , Mokrysheva N. G. 
Published: January 2024

Multiple endocrine neoplasia type 1 (MEN-1) is the orphan disease caused by the metachronous tumors of endocrine and non–endocrine organs. The first most frequent feature of the syndrome is primary hyperparathyroidism, however, manifestation from other components is also possible. Different medical specialists should know about this pathology because its clinical course is often varied.This clinical case of non-classical manifestation of MEN-1 demonstrates the difficulties of diagnostics, comprehensive examination and treatment of the main components of the syndrome. Timely laboratory, instrumental and genetic diagnostics plays an important role in the prevention of complications, improving the quality of life and prognosis of patients.
Power to the Users
Authors: Shadmy Tomer 
Published: January 2024

Abstract
Major online platforms deploy an array of policies and data-driven legislative and enforcement mechanisms, transforming economic, social, and technological powers into political might. While platforms use private law to legitimate the exercise of this form of power, the novel political relations and tools have a tremendous public impact, both on individuals’ and communities’ political freedom and on the public sphere. Digital rights literature that tends to focus on particular rights, such as privacy or freedom of expression, deals less with the implications of platforms’ emerging political authority. The article addresses this lacuna by (1) analyzing the quasi-sovereign power of platforms, (2) mapping how this form of power disrupts political freedom and the public sphere, (3) revealing a theoretical trap that blocks existing attempts to address the threats and (4) developing a bottom-up approach to resolve this bind. The article proposes the creation of “Users Unions” – legal structures that create affordance for users to have a collective voice within platforms’ corporate governance and decision-making mechanisms. The proposed structural reform could mitigate the power disparities between users and online platforms and assist in respecting, protecting, and fulfilling users’ political rights.
Exploring the impact of vibrational cavity coupling strength on ultrafast CN + c-C6H12 reaction dynamics
Authors: Chen Liying , Fidler Ashley P. , McKillop Alexander M. , Weichman Marissa L. 
Published: January 2024

Abstract
Molecular polaritons, hybrid light-matter states resulting from strong cavity coupling of optical transitions, may provide a new route to guide chemical reactions. However, demonstrations of cavity-modified reactivity in clean benchmark systems are still needed to clarify the mechanisms and scope of polariton chemistry. Here, we use transient absorption to observe the ultrafast dynamics of CN radicals interacting with a cyclohexane (c-C6H12) and chloroform (CHCl3) solvent mixture under vibrational strong coupling of a C–H stretching mode of c-C6H12. By modulating the c-C6H12:CHCl3 ratio, we explore how solvent complexation and hydrogen (H)-abstraction processes proceed under collective cavity coupling strengths ranging from 55 to 85 cm−1. Reaction rates remain unchanged for all extracavity, on-resonance, and off-resonance cavity coupling conditions, regardless of coupling strength. These results suggest that insufficient vibrational cavity coupling strength may not be the determining factor for the negligible cavity effects observed previously in H-abstraction reactions of CN with CHCl3.
Study hoop algebras by fuzzy (n-fold) obstinate filters
Authors: Namdar Ameneh , Saeid Arsham Borumand 
Published: January 2024

Abstract
In this article, we introduce the concept of fuzzy (n-fold) obstinate filter on hoop algebras and study some of the properties. We define and study fuzzy prime filter and fuzzy n-fold implicative filter on hoop algebras. Also, the relationship between fuzzy obstinate filter and some other fuzzy filters likeness fuzzy prime and fuzzy positive implicative filters are investigated. Then we show that the quotient of this structure is a Boolean algebra and obtained some condition equivalent with fuzzy n-fold implicative filter. Finally we show that every fuzzy n-fold obstinate filter with some conditions is a fuzzy n-fold implicative filter.
Experimental Study on Stability Analysis of Shallow-Buried Metro Station Hard Rock Excavation under Blasting Vibration Effect
Authors: Li Wei , Zhang Qingsong , Peng Yuxuan , Yu Liyuan , Bai Jiwen , Liu Yankai , Wang Zhiheng , Han Gang 
Published: January 2024

Abstract
By considering a certain metro station of Qingdao Metro Line 4 as the research object, a three-dimensional geotechnical testing model has been developed to analyze the stress and deformation characteristics of the surrounding rocks under blasting vibration effect. The simulation of the surrounding rock blasting process is achieved through an electric spark source. We conducted simulation tests on the excavation stability of shallow-buried hard rock metro stations with and without considering blasting damage effects, respectively. The stress, displacement, and primary support stress changing laws of the surrounding rock under different overburden thicknesses using the arch cover method and the primary support arch cover method have been revealed. Finally, we analyzed the applicability of the primary support arch cover method in terms of vault settlement, clearance convergence, and floor heave. Results show that the surrounding rock of the arch has roughly gone through three deformation stages, namely a slow deformation stage, rapid deformation stage, and stable deformation stage. Whether it is blasting excavation or non-blasting excavation, the settlement of the arch is within a safe and controllable range. Because of the refinement of the excavation process by the primary support arch cover method, the stress release is relatively stable throughout the entire excavation process, but the significant impact of blasting vibration on the surrounding rock cannot be ignored. The excavating of the left and right guide holes is the key process for the displacement and stress variation. The deformation and stress generated by the arch cover method have a small difference compared to the deformation and stress generated by the primary support arch cover method, indicating that the latter excavation method can be used under current engineering geological conditions. No large-area collapse and instability occurred in the experimental process, which provides a theoretical basis for similar projects.
Effect of high temperature thermal treatment on the electrochemical performance of natural flake graphite
Authors: Lähde Anna , Välikangas Juho , Meščeriakovas Arūnas , Karhunen Tommi , Meščeriakovė Sara-Maaria , Sippula Olli , Leinonen Seppo , Lassi Ulla , Jokiniemi Jorma 
Published: January 2024

AbstractNatural graphite is currently considered as a critical raw material in EU. The demand for graphite is still increasing as it is commonly used in the anodes of the Li-ion batteries (LIBs). The total graphite content for energy storage applications such as LIBs should be more than 99.95%. Several purification processes for natural graphite exist but the requirement of high purity is challenging. Here we present the high temperature thermal treatment for natural graphite ores. Thermal treatment at 2400 °C for 15 min can produce battery-grade graphite with high purity and crystallinity needed for the optimum performance of the battery cells. In addition, the crystallinity and crystalline structure of graphite was improved during the treatment. The electrochemical studies of thermally treated graphite powders showed increased electrochemical performance compared to the untreated graphite samples. The improved performance was attributed to the increased purity and crystallinity of the thermally treated powders.
Graphical Abstract
Oxygen-ion and proton conductivity in the Ba3InGa2O7.5 complex oxide with incomplete oxygen sublattice
Authors: Kochetova Nadezhda , Cherepanova Veronika , Pikalova Alyona , Gilev Artem 
Published: January 2024

The Ba3InGa2O7.5 complex oxide, possessing the perovskite-related structure with structural oxygen vacancies, was first synthesized by the solid state method. The phase was found to be characterized by monoclinic symmetry (sp. gr. P2/c) with the following unit cell parameters: a = 7.942(1) Å, b = 5.868(5) Å, c = 18.201(6) Å, b = 91.52(9). Comprehensive investigations of electrical properties were carried out; ceramic material based on the complex oxide was shown to be a predominantly ionic conductor in the temperature range 450–900 oC. The conductivity is due to oxygen-ion transfer in dry conditions and oxygen-ion and proton transfer in wet atmosphere. The proton conductivity value is 4.5·10–5 S/cm, and the proton transport number is ~50% at 700 oC in wet air; at lower temperatures, proton transport becomes dominant. Prolonged treatment of the sample in water vapors below 450 oC leads to hydrolysis decomposition.
The role of epigenetics in male and female infertility
Authors: Egorova D. A. , Derezina V. V. , Chebanyan M. V. , Sultonova M. B. , Ishmuratov T. V. , Gasanov M. M. , Chipchikova A. Z. , Paksileva S. A. , Mitkina S. S. , Khamidullina R. R. , Kutueva A. Sh. , Anikeeva A. A. 
Published: January 2024

Introduction. Today, infertility is a global problem that affects about 48.5 million married couples worldwide. It has been suggested that epigenetic aberrations are of great importance for reproductive health, as they account for an interactive relationship between genomic landscape, interplay with gene environment and disease phenotype. A new understanding on etiology of complex non-Mendelian disease traits has aroused a growing interest in reproductive epigenetics.Aim: to analyze available publications on epigenetic aspects of male and female infertility as well as nutrition-related risk factors.Materials and Methods. There was conducted a search for publications in the electronic databases PubMed, Google Scholar and Library to be selected in accordance with PRISMA recommendations. All relevant articles published before November 2023 were included in this review. As a result of the search, there were extracted 530 publications from PubMed, 57 publications – from eLibrary and 23 publications – from Google Scholar. Duplicates and non-full-text article versions were excluded.Results. Environmental factors play an important role in generation and maintenance of epigenetic marks. DNA methylation abnormalities can lower human fertility. Altered protamine level may affect epigenetic paternally transmitted DNA information. Long-term infertility is associated with a modified methylome in euploid blastocysts primarily affecting regulation of genomic imprinting. Both excess and deficiency of trace elements are associated with adverse pregnancy outcomes, similarly applied infertility.Conclusion. Despite that epigenetic mechanisms, genes, nutrition and dietary supplements discussed here affect infertility, while a relevant recommended dose has not yet been determined, it was noted that such parameters may positively influence fertility. However, more comprehensive and longitudinal human studies are required to examine their relationship to male and female reproductive functions.
Evaluation of Estonia’s enhanced care management program: protocol for a cluster randomized trial
Authors: Daniels Benjamin , Rogger Daniel , Mohammed Meyhar , Vaarsi Katre , Croke Kevin 
Published: January 2024

Background: Estonia’s aging population faces an increasing burden of non-communicable diseases (NCDs) and a growing population suffers with multiple chronic conditions. These changes have reduced well-being and quality of life for many older Estonians, while increasing the use of high cost specialist and emergency care. In response, the Estonia Health Insurance Fund (EHIF) is working to support primary care physicians to improve care for complex patients with multiple chronic conditions. A new EHIF program, Enhanced Care Management (ECM), trains family physicians to identify complex patients, co-develop proactive care plans with them, and conduct more active outreach and management of these patients.
Methods: In this protocol we describe a randomized controlled trial, developed in partnership with EHIF, to evaluate the impact of ECM training for physicians. The RCT enrolled a randomly selected 97 family physicians out of the 786 family physicians practicing in Estonia. Among those physicians’ 6,739 ECM-eligible patients, 2,389 patients were randomly selected for enrolment into the ECM program.
Results: Using administrative records, we evaluated the effects of ECM enrolment on: (1) health care utilization; (2) provider management of tracer conditions; and (3) markers of quality of care such as hospital admission for primary health care-sensitive conditions.
Conclusions: This protocol presents a pre-specified analysis plan for this evaluation of Estonia’s ECM program.
Trial registration: First registered with the American Economics Association, AEARCTR-0003661. Registered May 1, 2019. Retrospective secondary registration with www.clinicaltrials.gov P169891. Registered April 26, 2023.
СРПСКА ХЕМИЈСКА ТЕРМИНОЛОГИЈА У ДЕЛУ „HISTORIAE NATVRALIS” АНДРЕАСА ВОЛНОГ (1805)
Authors: Радоја Ксенија 
Published: January 2024

У оквиру овог рада анализирана је српска терминологија из области хемије, конкретније, називи хемијских елемената и једињења у делу Historiae natvralis elementa Андреаса Волног из 1805. године. Регистрована грађа најпре је приказана у виду речника, а потом и анализирана. Циљ овог истраживања јесте да се упореди терминолошки систем везан за дату област из предстандардне епохе с оним који је део стандардног српског језика. Посебна пажња посвећена је утврђивању разлога за губљење једних и чување других термина.
ANALISIS FAKTOR YANG BERHUBUNGAN DENGAN DERAJAT DRY EYE SYNDROME PADA PENGEMUDI OJEK ONLINE DI SEKITAR KAMPUS UNDIP TEMBALANG, KOTA SEMARANG
Authors: Tampubolon Abina Damayanti , Kurniawan Bina , Jayanti Siswi 
Published: January 2024

Ojek online merupakan alat transportasi masa kini yang juga menawarkan berbagai jenis layanan selain mengangkut penumpang. Pengemudi ojek online senantiasa bekerja di luar ruangan sehingga berisiko terpapar oleh polusi udara, angin, iklim kering dan panas. Paparan tersebut dapat menyebabkan gangguan kesehatan mata, salah satunya adalah dry eye syndrome (DES) atau sindrom mata kering. DES merupakan kondisi berkurangnya fungsi air mata yang menyebabkan permukaan mata tidak dapat dilumasi oleh air mata. Penelitian ini akan menganalisis hubungan beberapa faktor terhadap kejadian DES pada pengemudi ojek online di sekitar kampus Universitas Diponegoro Semarang. Penelitian ini adalah penelitian dengan jenis observasional analitik yang memiliki desain studi cross-sectional. Populasi penelitian adalah seluruh pengemudi ojek online aktif dengan sampel yang diambil sebanyak 54 orang. Variabel yang akan diteliti adalah usia, durasi kerja, masa kerja, penggunaan visor helm, serta derajat keluhan DES. Pengambilan data dilakukan dengan wawancara menggunakan kuesioner untuk setiap variabel bebas dan kuesioner ocular surface disease index (OSDI) untuk mengukur derajat keluhan DES. Hasil analisis penelitian menggunakan uji statistik chi-square menunjukkan kesimpulan bahwa terdapat hubungan antara faktor usia (p = 0,013), durasi kerja (p = 0,001), dan penggunaan visor helm (p = 0,001) dengan derajat keluhan DES pada pengemudi ojek online di sekitar kampus Universitas Diponegoro Semarang. Sementara itu, tidak terdapat hubungan antara masa kerja dengan derajat keluhan DES (p = 0,406). Penggunaan visor helm setiap berkendara dapat mengurangi paparan langsung dengan faktor lingkungan penyebab DES. Selain itu, penggunaan lubrikan/tetes mata dapat menangani gejala DES sementara.
Potential Rheumatoid Arthritis-Associated Interstitial Lung Disease Treatment and Computational Approach for Future Drug Development
Authors: Jeong Eun Ji , Hong Hyunseok , Kim Kyoung-Soo 
Published: January 2024

Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized by swelling in at least one joint. Owing to an overactive immune response, extra-articular manifestations are observed in certain cases, with interstitial lung disease (ILD) being the most common. Rheumatoid arthritis-associated interstitial lung disease (RA-ILD) is characterized by chronic inflammation of the interstitial space, which causes fibrosis and the scarring of lung tissue. Controlling inflammation and pulmonary fibrosis in RA-ILD is important because they are associated with high morbidity and mortality. Pirfenidone and nintedanib are specific drugs against idiopathic pulmonary fibrosis and have shown efficacy against RA-ILD in several clinical trials. Immunosuppressants and disease-modifying antirheumatic drugs (DMARDs) with antifibrotic effects have also been used to treat RA-ILD. Immunosuppressants moderate the overexpression of cytokines and immune cells to reduce pulmonary damage and slow the progression of fibrosis. DMARDs with mild antifibrotic effects target specific fibrotic pathways to regulate fibrogenic cellular activity, extracellular matrix homeostasis, and oxidative stress levels. Therefore, specific medications are required to effectively treat RA-ILD. In this review, the commonly used RA-ILD treatments are discussed based on their molecular mechanisms and clinical trial results. In addition, a computational approach is proposed to develop specific drugs for RA-ILD.
Congruent Concavity Restoration of the Reconstructed Glenoid After the Latarjet Procedure
Authors: Do Woo-Sung , Shin Seung-Hwan , Lim Joon-Ryul , Yoon Tae-Hwan , Chun Yong-Min 
Published: January 2024

Update
This article was updated on April 24, 2024 because of a previous omission, which was discovered after the preliminary version of the article was posted online. Specifically, the following blurb has been added to the first page of the PDF: “A Commentary by Inbo Kim, MD, PhD, is linked to the online version of this article.”

Background:
Few clinical studies have addressed concavity restoration by natural remodeling after a Latarjet procedure. This study investigated the fibrous tissue and osseous remodeling of the reconstructed glenoid and concavity restoration after a Latarjet procedure using postoperative computed tomographic arthrography (CTA).

Methods:
This retrospective study included 31 patients who underwent immediate postoperative computed tomographic (CT) scanning followed by CTA at 6 months postoperatively. We investigated whether fibrous tissue was newly created over the graft, whether the created fibrous tissue restored the congruity of the articular surface and the osseous remodeling of the graft to the glenoid level (whether the osseous portion of the graft was remodeled flush to the glenoid level) and the concavity of the glenoid using the radius of a best-fit circle on the articular surface, and the relationship between the amount of created fibrous tissue and the position of the graft.

Results:
In all patients, the fibrous tissue on the graft yielded a smooth articular surface, as revealed by the CTA. The mean radius of the entire glenoid, including the transferred graft, was significantly smaller (p = 0.010) at 33.2 ± 8.5 mm than that of the glenoid posterior to the osseous step-off at 37.6 ± 9.4 mm, which is presumed to be the glenoid before the surgical procedure. Despite the congruity of the articular surfaces due to fibrous tissue seen in the CTA, 14 (45%) of 31 patients showed a subchondral osseous step-off on either the medial side or the lateral side in the immediate postoperative CT scans. However, through osseous remodeling, 8 of the 10 grafts with a lateral step-off and 2 of the 4 grafts with a medial step-off converted to a flush position. The position of the step-off was correlated with the thickness of the fibrous tissue, with a tendency for thicker tissue in cases of a step-off on the medial side (p = 0.014).

Conclusions:
Fibrous tissue formation plus remodeling of the transferred graft resulted in the restoration of a congruent concavity after a Latarjet procedure by compensating for initially non-flush positioning of the graft. However, due to the small sample size in our study, clinical outcomes could not be correlated with radiographic findings, and our recommendation is to continue placing the graft as anatomically as possible.

Level of Evidence:
Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.