bluuebunny/crossref_metadata_2025_split huggingface dataset:
Natural killer (NK) and HLA-C in in hepatitis C virus infected patient in Egypt during infection with Covid 19
Authors: Talat Ahmed Mohamed , Hassan Ali Mustafa Ali , Nakeeb Seham Mohamed Saied El , Mansour Safy Kabeel Ali 
Published: November 2023

Abstract
Hepatitis C virus (HCV) infection develops into chronic hepatitis in over two-thirds of acute infections. While current treatments with Sovaldi and ribavirin achieve HCV eradication in >95% of cases, no vaccine is available and re-infection can readily occur. Natural killer (NK) cells represent a key cellular component of the innate immune system, participating in early defence against infectious diseases, viruses, and cancers. When acute infection becomes chronic, however, NK cell function is altered. the NK immune response is a double-edged sword that is a significant component of the innate immune antiviral response, but persistent activation can drive tissue damage during chronic infection. Natural killer (NK) and lymphocytes with NK receptors (NKRs) is thought to play a key role in determining whether host immune responses to hepatitis C virus (HCV) infection result in viral clearance or disease progression. The aim of the present work was to Study of some immunological cells (cd 16, cd 56), genetic factors (HLA-C) in hepatitis C virus infected patients. A total number of 60 patients were included in this study. Their age ranged from 38-62 years old. The included patients were classified into 3 groups: group IA and IB (n=40) including cases with positive HCV antibodies (HCV-Ab), but negative real-time PCR for HCV after treatment with Sovaldi and Ribavirin, and they were considered as Responders, group IA Infected with covid 19, while group IB not Infected with covid 19. While group II (n=20) including patients with HCV infection ( HCV-Ab positive and real-time PCR for HCV is positive ) after treatment with Sovaldiand Ribavirin ( Non responders ) Considered as Non Responders. And group III ( n=60 ) healthy persons with matched age, sex and environmental status also included as controls.
Post-Discharge Care Practices, Challenges and Outcomes in Newborn Infants of Mothers with SARS-CoV-2 Infection: Insights from Public Hospitals
Authors: Patil Uday P. , Gupta Arpit , Heringman Kevin , Hickman Cherbrale , Paudel Umesh , Wachtel Elena V. 
Published: November 2023

Abstract

Background
The data regarding the care at home and outcomes in infants of mothers infected with SARS-CoV-2 continues to evolve. There is a paucity of studies beyond the immediate newborn period. Our research aims to improve the understanding in these areas by studying the newborn population discharged from public hospitals in several boroughs of New York City (NYC) through the first year of the Covid-19 pandemic.
Objective
To assess parental perspective and describe post-discharge care practices, patterns of healthcare utilization, challenges obtaining care, and outcomes in infants between 6 to 12 months of age born to mothers infected with SARS-CoV-2 at the time of delivery.
Methods
We conducted an IRB-approved multi-center retrospective cohort study of infants born to SARS-CoV-2 positive mothers at 5 NYC public hospitals between March and December of 2020. Clinical and demographic data were collected from electronic medical records. A phone interview of the caregivers using a standard questionnaire was conducted to collect data about care at home, healthcare utilization patterns, and challenges with access to healthcare.
Results
Our study cohort included 216 infants born to SARS-CoV-2 positive mothers with 16 (7.4%) mothers being symptomatic at discharge. Ten infants tested positive and 2 showed symptoms before discharge. Two hundred and seven (95.8%) infants were discharged home and 202 (94%) were discharged to their parents. 138 (66%) infants had at least 1 visit to the emergency room for various complaints where 2 were found to have Covid-19 with 1 needing hospitalization. 172 (79.6%) families responded to the phone interview. Most mothers (78%) cohabitated with their infant at home and 70.3% elected to breastfeed. However, only 56.3% of mothers reported using all the recommended infection prevention practices at home. More than half (57%) of the families reported financial hardship related to the pandemic. Although 46.2% of patients missed their in-person health maintenance visits, telemedicine was highly utilized for follow up with most being phone visits (70.3%). The majority of the infants (95.5%) remained up-to-date with their routine immunizations. Results are summarized in tables 1–3.
Conclusions
Our results suggest that infants born to SARS-CoV-2 infected mothers showed increased utilization of medical care and telemedicine between 6–12 months of age. Mothers reported low adherence to infection prevention practices at home however infants rarely showed clinically significant SARS-CoV-2 infection while maintaining high breastfeeding rates after discharge.
MSCA-YOLO: Accurate Detection of Railway Track Anomalies Using Multi-scale Features
Authors: Zhang Yan , Li Kefeng , Zhang Guangyuan , Wang Zhenfei , Zhu Zhenfang , Fu Chen , Jiang Guangyuan 
Published: November 2023

Abstract
With the escalating demands of modern railroad traffic, ensuring the integrity and safety of rails has become paramount. Railroad track fasteners and sleepers, integral components of the railroad system, can pose significant safety risks if they develop cracks or sustain damage. To detect such potential issues both timely and accurately, this paper introduces a crack detection method for railroad track fasteners and sleepers, enhancing the MSCA-YOLO mechanism of YoloV8. First, we integrate a detection head tailored for small targets into the model, amplifying the detection capabilities for minute cracks. A multi-scale MSCA attention mechanism is proposed, heightening the model's focus on the target and subsequently improving recognition accuracy. To validate the efficacy of the proposed method, we carried out a series of experiments using a self-curated real railroad track dataset. Experimental results demonstrate that, compared to YoloV8, our approach boosts detection accuracy by 4.5%, recall rate by 1.2%, and achieves a 0.9% increase in mAP. Our model presents an effective and practical solution for safety monitoring within railroad systems.
Do multifunctional organisms and Chlorella sp. microalgae benefit the production of Hymenaea courbaril L. seedlings?
Authors: Biazatti Renan Marré , Santos Silvia Correa , Santos Cleberton Correia , Pinheiro Bruno Lenhart , de Carvalho Rafael Lima , de Medeiros Elias Silva , Scalon Silvana de Paula Quintão , Torales Elissandra Pacito 
Published: November 2023

Abstract
The use of Azospirillum brasilense and Chlorella sp. has gained popularity in agriculture and forestry due to the benefits they offer to plants. These two biological solutions have demonstrated potential to improve the performance and sustainability of crops and forest species, opening new perspectives for agriculture and the recovery of degraded areas. Given the importance of establishing management strategies for seedling production and that information for forest essences is insufficient, the aim of this study was to evaluate the effect of intervals of Chlorella sp. microalgae application and inoculation with Azospirillum brasilense doses on the growth and quality of Hymenaea courbaril L. seedlings. The experiment was conducted in a randomized block experimental design, and treatments were arranged in a 5 x 4 factorial scheme, with four replicates, testing five A. brasilense doses: 0, 3, 6, 9 and 12 mL/plant and four intervals of Chlorella sp microalgae application: single application and every 7, 14 and 21 after transplanting (DAT), for 120 days. Growth and photosynthetic parameters were evaluated. Inoculation with 6 and 9 mL of Azospirillum brasiliense, regardless of Chlorella sp. microalgae application favored the growth of H. courbaril seedlings. Chlorella sp. microalgae application at intervals of 14 and 21 days favored the responses of seedlings inoculated with Azospirillum brasilenses. The association between Azospirillum brasiliense and Chlorella sp. promoted gains in seedling production and quality.
IMITATIO SPECIEI GERMANICAE: INOCULTURAL INNOVATIONS IN THE FORM OF THE AESTII AND PRUSSIANS I–VI
Authors: КУЛАКОВ В.И. 
Published: October 2023

В предлагаемой главе при помощи письменных и археологических источников выявлен интереснейший исторический феномен. Часть западных балтов, непосредственно граничивших с восточными германцами, с I-II в. по минимум VII в. стремилась к подражанию деталям убора и, очевидно, внешнему виду германцев, причём — западных. Это стремление было основано на высоком авторитете, который был достигнут западной частью германских племён среди остального населения Barbaricum. Сами же германцы ко времени крушения Западной Римской империи всё больше старались походить на носителей провинциально-римской традиции. Даже первое готское государство в Италии, основанное в 476 г. Одоакром, формально считалось частью Восточной Римской империи. Упомянутые имитационные тенденции в сознании германцев позднеримского времени привели к возникновению лозунга Imitatio Imperii Romanorum, актуального при формировании основ будущей Священной Римской империи германской нации.
In the proposed chapter, with the help of written and archaeological sources, an interesting historical phenomenon is revealed. Part of the western Balts, directly bordering on the eastern Germans, from the 1st-2nd centuries. at least the 7th century strove to imitate the details of the dress and, obviously, the appearance of the Germans, moreover, the Western ones. This desire was based on the high prestige that was achieved by the western part of the Germanic tribes among the rest of the Barbaricum population. By the time of the collapse of the Western Roman Empire, the Germans themselves were increasingly trying to resemble the bearers of the provincial Roman tradition. Even the first Gothic state in Italy, founded in 476 by Odoacer, was formally considered part of the Eastern Roman Empire. The aforementioned imitative tendencies in the minds of the late Roman Germans led to the emergence of the slogan Imitatio Imperii Romanorum, relevant in the formation of the foundations of the future Holy Roman Empire of the German nation.
INTERPRETATION OF THE ROYAL PERIOD ROMAN HISTORY IN CHRISTIAN APOLOGIES
Authors: ХОРЬКОВА И.В. 
Published: October 2023

В главе речь идет об изложении римской истории царского периода в сочинениях христианских апологетов. В качестве критерия отбора материала избран этнолингвистический принцип, поэтому в статье рассматриваются только латиноязычные авторы. Помимо латинского языка апологетов этой группы объединяет общий ментальный субстрат, полемические приемы и общие источники информации. В статье анализируются различные примеры интерпретации латинскими апологетами событий древнейшей римской истории с целью определения ее общих черт и задач. В результате исследования делается вывод, что основной задачей христианских авторов при рассмотрении ранней римской истории является дискредитация римской старины. При этом апологетами используется тенденциозный отбор материала, рациональная критика событий, негативная морально-нравственная и правовая оценка.
This chapter deals with the presentation of the Roman history of the royal period in the writings of Christian apologists. The ethnolinguistic principle was chosen as a criterion for the selection of material, therefore, only Latin-speaking authors are considered in the article. In addition to the Latin language, apologists of this group combine a common mental substrate, polemical techniques and common sources of information. The article analyzes various examples of Latin apologists' interpretation of the events of ancient Roman history in order to determine its common features and challenges. As a result of the study, it is concluded that the main task of Christian authors when considering early Roman history is to discredit Roman antiquity. Apologists use tendentious selection of material, rational criticism of events, negative moral and legal assessment.
«BARBARIAN ANTIQUITY» OR «DECREPIT MODERNITY»? FORMATION OF THE «ADVANCEMENT OF LEARNING» CONCEPT IN THE AGE OF QUEEN ELIZABETH AND JACOB I
Authors: ШПАК Г.В. 
Published: October 2023

На протяжении XX в. исследователи использовали разнообразные подходы к изучению истории знания, зачастую выстраивая прямую, ведущую от невежественного прошлого к прогрессивной современности. Даже авторы, призывающие к осторожности, в силу риторических особенностей текста представляли развитие науки как поступательный процесс накопления истин, не учитывая их конструктивный характер. Концепт «Научная революция», используемый в качестве исторической рамки в широком смысле подразумевал коренную трансформацию рецептивно-репрезентативных практик, произошедших в границах 1543 и 1687 гг. Как хронологические, так и территориальные границы этого концепта не могут быть четко обозначены в связи с его конструктивной природой. В силу этого формируется представление о разрыве между знанием прошлого и всем, что было до «Научной революции». В Англии конца XVI – первой четверти XVII в. происходила трансформация восприятия времени, которая шла параллельно с так называемой «борьбой древних и новых», когда современные практики описания реальности были объявлены более релевантными, чем практики прошлого. Это привело к тому, что уже в XVIII в. французские просветители начали говорить о революции, произошедшей в познании, а все что относилось к предшествующему времени было объявлено невежественным и варварским.
Throughout the XX century researchers used a variety of approaches to the study of the history of knowledge, often describing a straight line leading from the ignorant past to the progressive modernity. Even the authors calling for caution due to the rhetorical features of the text presented the development of science as a progressive process of accumulating truths, often not taking into account the constructive nature of knowledge. The concept of “Scientific Revolution”, used as a historical framework in a broad sense, implied a radical transformation of the receptive-representational practices that occurred within the boundaries of 1543 and 1687. Both chronological and territorial boundaries of this concept cannot be clearly defined due to its constructive nature. Because of this, the idea of a gap between knowledge of the past and everything that was before the “Scientific Revolution” appeared. In England at the end of the 16th century and the first quarter of the 17th century, a transformation in the perception of time took place, which went in parallel with the so-called “Quarrel of the Ancients and the Moderns”, when modern practices of describing reality were declared more relevant than those of the past. This led to the fact that already in the 18th century, the French enlighteners began to talk about the revolution that had taken place in knowledge, and everything that related to the previous time was declared ignorant and barbaric.
HISTORICAL MODEL OF VERBAL BARBARITY
Authors: БУДАНОВА В.П. 
Published: October 2023

На основе исследования письменной традиции рубежа Античности и Средневековья представлена историко-лингвистическая характеристика языковых особенностей дискурса варварства. В качестве концептуальной основы используются модели вербального варварства. Концепт «вербальное варварство» впервые применяется для обозначения словесного проявления побуждения к злонамеренному действию, содержащего угрозу, с целью спровоцировать агрессию, физическое насилие, причинить ущерб, психологическую боль и ментальные страдания. Анализируется лексико-семантическая целеориентированность образа и сценария вербального поведения варвара в «Res gestae» Аммиана Марцеллина и «Getica» Иордана. Представлены описательные, экспрессивные, оценочные и орективные функциональные особенности словоупотребления с пейоративной семантикой. Автор приходит к заключению, что в системе позднеантичного и раннесредневекового дискурса варварства вербальная характеристика варвара и лексемы злословия отличались эмоционально-психологическим императивным воздействием, выявляя взаимосвязь физической и теневой стороны злонамеренного действия.
Based on the study of the written tradition of the turn of Antiquity and the Middle Ages, the historical and linguistic characteristics of the linguistic features of the discourse of barbarism are presented. Models of verbal barbarism are used as a conceptual basis. The concept of «verbal barbarism» is used for the first time to denote the verbal manifestation of an incentive to malicious action containing a threat in order to provoke aggression, physical violence, cause damage, psychological pain and mental suffering. The lexico-semantic goal orientation of the image and scenario of the verbal behavior of the barbarian in the «Res gestae» by Ammian Marcellin and «Getica» by Jordan is analyzed. Descriptive, expressive, evaluative and indicative functional features of word usage with pejorative semantics are presented. The author comes to the conclusion that in the system of late Antique and early medieval discourse of barbarism, the verbal characteristics of the barbarian and the lexemes of slander differed in emotional and psychological imperative effects, revealing the relationship between the physical and shadow side of malicious action.
ESTUDO BIBLIOMÉTRICO SOBRE INDICADORES DE DESEMPENHO NA GESTÃO HOSPITALAR
Authors: Ananine Paiva Erika , M. da Silva Fabrizio 
Published: October 2023

Objetivo: apresentar um estudo bibliométrico sobre Indicadores de Desempenho na gestão hospitalar. Método: Foi utilizada uma revisão bibliométrica. Optou-se pela utilização da base de dados Web of Science para a coleta de dados e os softwares “Bibliometrix” e “StudioR” para a análise dos dados. A estratégia metodológica para buscar material científico foi realizada da seguinte maneira: foram utilizadas palavras chaves, tais como: “performance indicator”, “hospital management” e “performance” na busca científica. No total, obtivemos um número de 296 documentos. Não foi empregado corte temporal na amostragem, desse modo, a pesquisa abrangeu materiais de 1945, data de fundação da base Web of Science, até 2021, quando foi feito o levantamento. Foram analisados, no primeiro momento, dados sobre os autores, periódicos e documentos. No segundo momento, a análise abordou a estrutura conceitual e intelectual. Fundamentação teórica: foi apresentado uma evolução temporal acerca das publicações científicas sobre indicadores de desempenho na gestão hospitalar com diferentes focos na organização hospitalar. Resultado: Entre os principais resultados encontrados na análise, foi possível constatar que a amostra teve início em 1988, porém o tema começou a ganhar grande volume de publicações a partir de 2005, tendo maior número de documentos publicados em 2020, chegando a 43. Os autores em destaque são: Amos D; Au-Yong CP; Liu HC e Musa ZN, com 4 documentos cada. A área com maior quantidade de publicações Health Care Sciences Services juntamente com Health Policy Services com 56 documentos cada. O principal periódico é a Revista International Journal for quality in Health Care com 8 documentos. As palavras mais citadas são: Hospitals / hospital (34), Performance indicators e quality indicators (17), Performance; performance measurement (16). Por fim, não menos importante, quando analisada a estrutura conceitual desses materiais, é possível identificar dois grupos bem significativos, com grande quantidade de publicações: Quality indicators e Performance Management. A partir da análise da estrutura intelectual, feita por meio da Cocitação, foi possível identificar cinco grupos, com foco na gestão hospitalar e sistema de medição de desempenho, (Kaplan) voltados para qualidade na prestação de serviços, (Donabedian), na qualidade e segurança do paciente, (Shortell SM; Berwick, SM), relacionados a Medicina geral e interna, (Peterson, ED e Fonarow, GC), e por fim, um grupo que tem relação direta e características nas quatros áreas discorridas anteriormente, destaque para o autor (Ruter).
Palavras chaves: Indicadores de desempenho; Gestão hospitalar; Performance
Intravenous Thrombolysis is Effective in Mild Stroke Patients with an Admission NIHSS Score of 3 to 5
Authors: Zhang Kai , Han Lin 
Published: November 2023

Background and Purpose:
The role of intravenous thrombolysis in patients with
acute mild ischemic stroke remains highly controversial. Therefore, this study aims to analyze
the efficacy and safety of intravenous thrombolysis in patients with mild ischemic stroke based
on admission National Institutes of Health Stroke Scale (NIHSS) score.

Methods:
The present study enrolled 507 patients with acute mild ischemic stroke admitted
within 4.5 hours of symptom onset with an admission NIHSS score of 0 to 5. Patients were assigned
to two groups based on admission NIHSS scores of 0 to 2 and 3 to 5, and subsequent
analyses compared functional outcomes between thrombotic and non-thrombotic patients within
these groups. The primary outcome was a modified Rankin score (mRS) of 0 or 1 at 90 days,
representing functional independence. The safety outcomes were symptomatic intracranial hemorrhage
(sICH), early neurological deterioration (END), and the rate of stroke recurrence within
90 days.

Results:
Among the 267 patients with NIHSS scores of 0 to 2, 112 (41.9%) patients received
intravenous thrombolysis. Overall, thrombolysis administration did not significantly improve the
patient's functional prognoses at 90 days (adjusted OR=1.046, 95%CI=0.587-1.863, p = 0.878).
However, there was a marked increase in the risk of sICH (p = 0.030). Of the 240 patients with
NIHSS scores of 3 to 5, 155 (64.6%) patients received intravenous thrombolysis, resulting in a
significant improvement in 90-day functional prognosis (adjusted OR=3.284, 95%CI=1.876-
5.749, p<0.001) compared to those that did not receive thrombolysis intervention. Importantly,
there was no significant increase in sICH incidence (adjusted OR=2.770, 95%CI=0.313-24.51, p
= 0.360). There were no statistically significant differences in END or the rate of stroke recurrence
within 90 days between thrombotic and non-thrombotic groups.

Conclusions:
Intravenous thrombolysis is safe and effective in patients with baseline NIHSS
scores of 3 to 5. In contrast, it did not improve 90-day functional outcomes in patients with
NIHSS scores of 0 to 2 and instead increased the risk of sICH.