bluuebunny/crossref_metadata_2025_split huggingface dataset:
Current evidence on the effectiveness of Ready-to-Use Supplementary Foods in children with moderate acute malnutrition: a systematic review and meta-analysis
Authors: Teshome Melese Sinaga , Lema Tefera Belachew , Abessa Teklu Gemechu , Mingels Sarah , Granitzer Marita , Rameckers Eugene , Verbecque Evi 
Published: January 2024

Abstract
Moderate acute malnutrition (MAM) is defined by a weight-for-height Z-score (WHZ) between −3 and −2 of the WHO reference or by a mid-upper arm circumference (MUAC) of ≥11⋅5 and <12⋅5 cm. This study aimed to synthesise the evidence for the effectiveness of Ready-to-Use Supplementary Food (RUSF) compared to other dietary interventions or no intervention on functioning at different levels of the International Classification of Functioning, Disability, and Health (ICF) among children with MAM between 2 and12 years old. Three databases (PubMed, Scopus, and Web of Science) were systematically searched (last update: 20 November 2022). Pooled estimates of effect were calculated using random-effects meta-analyses. The level of evidence was estimated with the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) method. Seven studies were included. RUSF had a significant small-sized better effect (pooled mean: 0⋅38; 95 % CI = [0⋅10, 0⋅67], P = 0⋅01, I² = 97 %) on different anthropometric measurements compared to other dietary interventions among MAM children (n 6476). Comparing RUSF with corn–soy blend Plus Plus (CSB++) showed that RUSF had a small-sized but significantly better effect on the children's anthropometric measures compared to children who received CSB++ (pooled mean: 0⋅16; 95 % CI = [0⋅05, 0⋅27], P = 0⋅01; I2 = 35 %). MAM children treated with RUSF had a better recovery rate compared to those treated with CSB++ (pooled risk difference: 0⋅11; 95 % CI = [0⋅06, 0⋅11], P < 0⋅001; I2 = 0 %). The RUSF intervention seems promising in improving MAM children's nutritional outcomes and recovery rate compared to other dietary interventions.
Scrolling back: Remediation within and through digital memory work
Authors: Annabell Taylor 
Published: January 2024

Abstract
This article explores how the concept of remediation is part of digital memory work performed by young women on Instagram. While remediation has been used to make sense of the ways sites of memory are represented across time and through different media, mnemonic media practices and forms are remediated in digital memory work. This article draws on interviews, observations of Instagram activities, and focus group data to analyse how other media practices and forms are integrated into digital memory work on Instagram and mobilised by young women to make sense of their mnemonic use of the platform. The analysis focuses on how practices of digital memory work use direct remediation of material objects and remediation of the functionality of mnemonic media practices. It addresses how the comparisons participants make to other mnemonic media practices reveal how digital memory work involves negotiation of personal and public, private and professional, and the authentic and staged. In addition, it grapples with the way that sharing happy experiences and moments to produce a ‘highlight reel’ or ‘hall of fame’ in postfeminist digital culture has valuable and potentially harmful implications.
A new species of Versteria (Cestoda: Taeniidae) parasitizing Neogale vison and Lontra canadensis (Carnivora: Mustelidae) from Western Canada
Authors: Shanebeck K.M. , Bennett J. , Green S.J. , Lagrue C. , Presswell B. 
Published: January 2024

Abstract
Via molecular and morphological analyses, we describe adult specimens of a new species of Versteria (Cestoda: Taeniidae) infecting mink and river otter (Carnivora: Mustelidae) in Western Canada, as well as larval forms from muskrat and mink. These sequences closely matched those reported from adult specimens from Colorado and Oregon, as well as larval infections in humans and a captive orangutan. We describe here a new species from British Columbia and Alberta (Canada), Versteria rafei n. sp., based upon morphological diagnostic characteristics and genetic distance and phylogeny. Versteria rafei n. sp. differs from the three other described species of the genus in the smaller scolex and cirrus sac. It also differs from V. mustelae (Eurasia) and V. cuja (South America) by having an armed cirrus, which is covered in hair-like bristles, and in the shape of its hooks, with a long thorn-like blade, and short or long handle (vs. a short sharply curved blade and no difference in handle size in previously described species). The poorly known V. brachyacantha (Central Africa) also has an armed cirrus and similarly shaped hooks. However, it differs from the new species in the number and size of hooks. Phylogenetic analysis of the cox1 and nad1 mitochondrial regions showed that our specimens clustered with isolates from undescribed adults and larval infections in North America, and separate from V. cuja, confirming them to be a distinct species from the American Clade.
Myxomatous degeneration of cardiac valves in a fetus with 6q25.1 (TAB2) deletion
Authors: Karmegaraj Balaganesh 
Published: January 2024

AbstractMyxomatous degeneration of one or more cardiac valves has been reported in trisomy 18, Noonan, Marfan, and Ehlers-Danlos syndromes. 6q25.1 (TAB2) deletion is one of the notable causes for myxomatous degeneration of cardiac valves. Whole exome sequencing must be considered in these subsets of cases for effective prenatal counselling. A 23-week fetus presented with cardiomegaly, redundant myxomatous tricuspid, mitral valve leaflets, thickened pulmonary valve, and bicuspid aortic valves detected to have 6q25.1 (TAB2) deletion was presented with literature review.
Large‐Scale Summertime Variability of Carbonate Chemistry Across the East Siberian Sea: Primary Production Versus Ikaite Dissolution
Authors: Sun Xiaole , Anderson Leif G. , Dessirier Benoît , Geibel Marc , Mörth Carl‐Magnus , Humborg Christoph 
Published: January 2024

AbstractSea‐ice dynamics can affect carbon cycling in polar oceans, with sea‐ice ikaite acting as a potentially important carbon pump. However, there is no large‐scale direct field evidence to support this. Here we used a unique data set that combined continuous measurements of atmospheric and water CO2 concentrations with water chemistry data collected over 1,200 km along the East Siberian Sea, the widest Arctic shelf sea. Our results reveal large spatial heterogeneity of sea‐ice ikaite contents, which directly interact with carbonate chemistry in the water column. Our findings demonstrate that the CO2 drawdown by sea‐ice ikaite dissolution could be as important as that by primary production. We suggest that the role of ikaite in regulating the seasonal carbon cycle on a regional scale could be more important than we previously thought. Effects of the warmer climate on sea ice loss might also play a role in the ikaite inventory.
Zircon U‐Pb‐He Double Dating of Modern Sands From the Inn River Catchment: Assessing Resolution and Potential in a Complex Orogenic Setting
Authors: Dunkl I. , Malis F. , Lünsdorf N. K. , Schönig J. , von Eynatten H. 
Published: January 2024

AbstractZircon U‐Pb‐He double dating (ZDD) provides the opportunity to derive high temperature crystallization ages and low temperature cooling ages from the very same mineral grain, making it especially attractive for zircon provenance studies. We present the combination of in situ detrital zircon U‐Pb‐He double dating and Raman spectroscopy‐based heavy mineral analysis on different tributaries of the Inn river system applying a new grain embedding technique. The Inn river catchment drains a well‐studied complex nappe pile of the Eastern Alps exposing Austroalpine and Penninic crystalline basement rocks. Igneous formations of different emplacement ages, as well as various metasedimentary units, have experienced Alpine and diverse pre‐Alpine metamorphic overprints. This makes the area ideally suited for testing the sensitivity and potential of ZDD for fingerprinting various lithologically contrasting units with contrasting thermal histories. Results demonstrate that both high‐ and low‐temperature age distributions reflect the major sources and thermotectonic pulses, respectively. More specifically, the rocks of the Tauern Window with Miocene (U‐Th)/He ages as well as the Permian metagranitoids from the Tauern and the Err‐Bernina nappe in the uppermost Inn valley are recorded in the downstream Inn sample. The main mass of zircons in the lower Inn, however, derives from the Ötztal and Silvretta crystalline basement rock with Cadomian U‐Pb and Cretaceous (U‐Th)/He ages. The abundance of heavy minerals derived from metamafic formations shows no correlation to the area of such lithologies on the catchments and the different zircon fertility resulted in the overrepresentation of zircon U‐Pb ages from the Variscan igneous suites.
The Signature of Climate in Fluvial Suspended Sediment Records
Authors: Chapman W. A. L. , Finnegan N. J. 
Published: January 2024

AbstractArid regions are often characterized by exceptionally high rates of fluvial sediment transport, but the processes responsible for this apparent connection between climate and sediment transport remain unclear. We examined decades of continuous flow records and suspended sediment concentrations from 71 rivers across the United States by comparing the suspended sediment rating curve behavior, quantified using power law coefficients and exponents, to an aridity index. Results indicate that higher aridity correlates with both greater overall suspended sediment concentration and lower sensitivity of concentration to changes in discharge, demonstrating that rivers in arid locations on average have greater suspended sediment transport efficiency across most discharges, and achieve high transport rates at a relatively lower discharge than rivers in temperate climates. Furthermore, based on additional analyses of the Normalized Difference Vegetation Index, specific suspended sediment yield, and a hydrograph flashiness index, we attribute the relationships between sediment transport and climate primarily to differences in vegetation density, precipitation, and runoff, variables that all influence both sediment supply and riverbed grain sorting. Finally, we note that the observed contrasts in sediment transport behavior likely represent climate‐driven differences in the magnitude and frequency of sediment supply rather than annual suspended sediment load, which does not depend significantly on climate. This study highlights a critical connection between multiple interrelated climatic factors and sediment transport, an important finding for future hazard mitigation in a changing climate with rapidly shifting vegetation patterns and hydrology.
Assessing Phytoplankton Primary Productivity Variability in the Changjiang Estuary, East China Sea From Coupled Fast Repetition Rate (FRR) Fluorometry and Chlorophyll‐a Measurements
Authors: Zhu Yuanli , Hughes David J. , Feng Yuanyuan , Browning Thomas J. , Du Ping , Meng Qicheng , Wang Shengqiang , Wang Bing , Li Dewang , Jiang Zhibing , Zeng Jiangning 
Published: January 2024

AbstractPhytoplankton primary productivity (PP) varies significantly over environmental gradients, particularly in physically‐dynamic systems such as estuaries and coastal seas. During summer, runoff peaks in the Changjiang River driving large environmental gradients in both the Changjiang estuary and adjacent East China Sea (ECS), likely driving significant variability in PP. As satellite models of PP often underperform in coastal waters, we aimed to develop a novel approach for assessing net PP variability in such a dynamic environment. Parallel in situ measurements of Fast Repetition Rate (FRR) fluorometry and carbon (C) uptake rates were conducted for the first time in this region during two summer cruises in 2019 and 2021. A series of 13C‐incubations (n = 31) were performed, with measured PP ranging from ∼6 to 1,700 mgC m−3 d−1. Net PP values were significantly correlated with salinity (r = 0.45), phytoplankton chlorophyll a (Chl‐a, r = 0.88), Photosystem II (PSII) functional absorption cross‐section (σPSII, r = −0.76) and maximum PSII quantum yield (Fv/Fm, r = 0.59). Stepwise regression analysis showed that Chl‐a and σPSII were the strongest predictors of net PP. A generalized additive model (GAM) was also used to estimate net PP considering nonlinear effects of Chl‐a and σPSII. We demonstrate that GAM outperforms linear modeling approaches in estimating net PP in this study, as evidenced by a lower root mean square error (∼140 vs. 250 mgC m−3 d−1). Our novel approach provides a valuable tool to examine carbon cycling dynamics in this important region.
Programmable synthetic receptors: the next-generation of cell and gene therapies
Authors: Teng Fei , Cui Tongtong , Zhou Li , Gao Qingqin , Zhou Qi , Li Wei 
Published: January 2024

AbstractCell and gene therapies hold tremendous promise for treating a range of difficult-to-treat diseases. However, concerns over the safety and efficacy require to be further addressed in order to realize their full potential. Synthetic receptors, a synthetic biology tool that can precisely control the function of therapeutic cells and genetic modules, have been rapidly developed and applied as a powerful solution. Delicately designed and engineered, they can be applied to finetune the therapeutic activities, i.e., to regulate production of dosed, bioactive payloads by sensing and processing user-defined signals or biomarkers. This review provides an overview of diverse synthetic receptor systems being used to reprogram therapeutic cells and their wide applications in biomedical research. With a special focus on four synthetic receptor systems at the forefront, including chimeric antigen receptors (CARs) and synthetic Notch (synNotch) receptors, we address the generalized strategies to design, construct and improve synthetic receptors. Meanwhile, we also highlight the expanding landscape of therapeutic applications of the synthetic receptor systems as well as current challenges in their clinical translation.
Systemwide energy return on investment in a sustainable transition towards net zero power systems
Authors: Sahin Hasret , Solomon A. A. , Aghahosseini Arman , Breyer Christian 
Published: January 2024

AbstractThe Glasgow Climate Pact articulated the vital importance of renewables in reducing emissions on the way to net-zero pledges. During the power sector transition, foreseeing conditions affecting the plausibility of pathway options is crucial for specifying an optimal system development strategy. This study examines the net energy performance of nine decarbonisation global energy transition scenarios until 2050 by applying a newly developed systemwide energy return on investment (EROI) model. All scenarios result in an EROI value above the upper limit of the net energy cliff, expected to be around 10. EROI trends heavily depend on transition paths. Once achieving higher renewable energy shares begin requiring significant enabling technologies, EROI continually declines as the shares increase. Shortening the transition period leads to a sharper declining of EROI, which stabilises after achieving 100% renewables. The vulnerability arising from natural gas and oil depletions may have worst impact on EROI of fossil fuels dominated systems.
Higher emissions scenarios lead to more extreme flooding in the United States
Authors: Kim Hanbeen , Villarini Gabriele 
Published: January 2024

AbstractUnderstanding projected changes in flooding across the contiguous United States (CONUS) helps increase our capability to adapt to and mitigate against this hazard. Here, we assess future changes in flooding across CONUS using outputs from 28 global climate models and four scenarios of the Coupled Model Intercomparison Project Phase 6. We find that CONUS is projected to experience an overall increase in flooding, especially under higher emission scenarios; there are subregional differences, with the Northeast and Southeast (Great Plains of the North and Southwest) showing higher tendency towards increasing (decreasing) flooding due to changes in flood processes at the seasonal scale. Moreover, even though trends may not be detected in the historical period, these projected future trends highlight the current needs for incorporating climate change in the future infrastructure designs and management of the water resources.
Reversible modulation of interlayer stacking in 2D copper-organic frameworks for tailoring porosity and photocatalytic activity
Authors: You Pei-Ye , Mo Kai-Ming , Wang Yu-Mei , Gao Qiang , Lin Xiao-Chun , Lin Jia-Tong , Xie Mo , Wei Rong-Jia , Ning Guo-Hong , Li Dan 
Published: January 2024

AbstractThe properties of two-dimensional covalent organic frameworks (2D COFs), including porosity, catalytic activity as well as electronic and optical properties, are greatly affected by their interlayer stacking structures. However, the precise control of their interlayer stacking mode, especially in a reversible fashion, is a long-standing and challenging pursuit. Herein, we prepare three 2D copper-organic frameworks, namely JNM-n (n = 7, 8, and 9). Interestingly, the reversible interlayer sliding between eclipsed AA stacking (i.e., JNM-7-AA and JNM-8-AA) and staggered ABC stacking (i.e., JNM-7-ABC and JNM-8-ABC) can be achieved through environmental stimulation, which endows reversible encapsulation and release of lipase. Importantly, JNM-7-AA and JNM-8-AA exhibit a broader light absorption range, higher charge-separation efficiency, and higher photocatalytic activity for sensitizing O2 to 1O2 and O2•− than their ABC stacking isostructures. Consequently, JNM-8-AA deliver significantly enhanced photocatalytic activities for oxidative cross-coupling reactions compared to JNM-8-ABC and other reported homogeneous and heterogeneous catalysts.
Programmable adhesion and morphing of protein hydrogels for underwater robots
Authors: Huang Sheng-Chen , Zhu Ya-Jiao , Huang Xiao-Ying , Xia Xiao-Xia , Qian Zhi-Gang 
Published: January 2024

AbstractSoft robots capable of efficiently implementing tasks in fluid-immersed environments hold great promise for diverse applications. However, it remains challenging to achieve robotization that relies on dynamic underwater adhesion and morphing capability. Here we propose the construction of such robots with designer protein materials. Firstly, a resilin-like protein is complexed with polyoxometalate anions to form hydrogels that can rapidly switch between soft adhesive and stiff non-adhesive states in aqueous environments in response to small temperature variation. To realize remote control over dynamic adhesion and morphing, Fe3O4 nanoparticles are then integrated into the hydrogels to form soft robots with photothermal and magnetic responsiveness. These robots are demonstrated to undertake complex tasks including repairing artificial blood vessel, capturing and delivering multiple cargoes in water under cooperative control of infrared light and magnetic field. These findings pave an avenue for the creation of protein-based underwater robots with on-demand functionalities.
Frequency-hopping wave engineering with metasurfaces
Authors: Takeshita Hiroki , Fathnan Ashif Aminulloh , Nita Daisuke , Nagata Atsuko , Sugiura Shinya , Wakatsuchi Hiroki 
Published: January 2024

AbstractWave phenomena can be artificially engineered by scattering from metasurfaces, which aids in the design of radio-frequency and optical devices for wireless communication, sensing, imaging, wireless power transfer and bio/medical applications. Scattering responses vary with changing frequency; conversely, they remain unchanged at a constant frequency, which has been a long-standing limitation in the design of devices leveraging wave scattering phenomena. Here, we present metasurfaces that can scatter incident waves according to two variables—the frequency and pulse width—in multiple bands. Significantly, these scattering profiles are characterized by how the frequencies are used in different time windows due to transient circuits. In particular, by using more than one frequency with coupled transient circuits, we demonstrate variable scattering profiles in response to unique frequency sequences, which can break a conventional linear frequency concept and markedly increase the available frequency channels in accordance with a factorial number of frequencies used. Our proposed concept, which is analogous to frequency hopping in wireless communication, advances wave engineering in electromagnetics and related fields.
Probabilistic state synthesis based on optimal convex approximation
Authors: Akibue Seiseki , Kato Go , Tani Seiichiro 
Published: January 2024

AbstractWhen preparing a pure state with a quantum circuit, there is an unavoidable approximation error due to the compilation error in fault-tolerant implementation. A recently proposed approach called probabilistic state synthesis, where the circuit is probabilistically sampled, is able to reduce the approximation error compared to conventional deterministic synthesis. In this paper, we demonstrate that the optimal probabilistic synthesis quadratically reduces the approximation error. Moreover, we show that a deterministic synthesis algorithm can be efficiently converted into a probabilistic one that achieves this quadratic error reduction. We also numerically demonstrate how this conversion reduces the T-count and analytically prove that this conversion halves an information-theoretic lower bound on the circuit size. In order to derive these results, we prove general theorems about the optimal convex approximation of a quantum state. Furthermore, we demonstrate that this theorem can be used to analyze an entanglement measure.
ITGB4 upregulation is associated with progression of lower grade glioma
Authors: Chen Pengyu , Ma Tuo , Yan Tianfang , Song Zhenhua , Liu Chengyong , Pan Chao , Zhang Baoshuang , Wei Danian , Wang Guohui 
Published: January 2024

AbstractGliomas originating in the neuroepithelium account for about 80% of brain malignancies and are the most common cancer of the central nervous system. Clinical management of gliomas remains challenging despite significant advances in comprehensive therapies, including radiotherapy, chemotherapy, and surgery. The ITGB4 (Integrin subunit beta 4) gene encodes a receptor for laminins and its upregulation in tumor tissues is associated with poor prognosis. However, its role in glioma is not well understood. First, we performed a pan cancer analysis of ITGB4 expression in The Cancer Genome Atlas (TCGA) dataset. Survival analysis was done on Chinese Glioma Genome Atlas (CGGA) and TCGA. Immunohistochemistry was then used to validate the expression and role of ITGB4 in glioma. We finally analyzed the possible mechanism by immune infiltration and single-cell sequencing analysis. Here, we found that ITGB4 is upregulated in glioma and accurately predicts the prognosis of lower grade glioma (LGG). Univariate and multivariate Cox regression analyses showed that ITGB4 is a risk factor for LGG. Immunohistochemical analysis confirmed that ITGB4 accurately predicts LGG prognosis. Non-negative matrix factorization (NMF) cluster analysis showed that ITGB4 was closely related to immune related genes. Immune cell infiltration and single cell sequencing analyses indicated that ITGB4 may be closely related to the microenvironment of gliomas, especially tumor-associated fibroblasts. ITGB4 is a promising diagnostic and therapeutic factor in LGG patients.