bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fin de l’élimination des poussins mâles d’un jour : le choix du sexage in ovo
Authors: REHAULT-GODBERT Sophie , BOURIN Marie , GAUTRON Joël , QUENTIN Maxime 
Published: December 2023

Une problématique majeure de la filière avicole est l’absence de valorisation des frères des poules pondeuses, du fait de leur faible rendement en viande. Ce constat, qui questionne l’éthique de la production, concerne 50 millions de poussins mâles en France et 7,5 milliards dans le monde, ces animaux étant jusqu’à récemment, éliminés après sexage et tri à l’éclosion. Cette prise de conscience, largement médiatisée ces dernières années, a conduit à la publication d’un décret, le 5 février 2022, interdisant la mise à mort des mâles des lignées de l’espèce Gallus gallus destinées à la production des œufs de consommation. Trois alternatives ont été proposées depuis les premières réflexions sur le sujet : 1) élever les frères de pondeuses et identifier des marchés de valorisation, 2) créer de nouveaux croisements génétiques entre souches « Chair » et souches « Ponte » où les descendantes femelles seraient valorisées pour les œufs et les descendants mâles pour leur viande (souches « mixtes »), et 3) développer des outils de sexage in ovo (ou ovosexage) pour détecter puis éliminer les œufs contenant un embryon mâle avant éclosion. Cette dernière approche est la seule viable techniquement et économiquement parlant, et utilisable par la filière actuellement. Elle réunit de nombreux atouts, en termes de faisabilité pour la mise en œuvre dans les couvoirs, et d’acceptabilité à la fois par le consommateur, le citoyen et les professionnels. Cette revue fait le point sur le contexte socio-économique et les techniques d’ovosexage actuellement disponibles, tout en introduisant quelques repères physiologiques d’embryologie aviaire qui permettent de mieux comprendre les contraintes associées au développement de techniques à des stades précoces de développement.
SOCIAL DISCRIMINATION: A CASE STUDY OF SOCIAL SUBORDINATION TO BAHASA INDONESIA OF VERNACULAR EASTERN INDONESIAN
Authors: Wijaya Ayudhia Ratna , Rizal Cesar Abdul 
Published: December 2023

<span>This research aims to explain the correlation between <em>Bahasa Indonesia</em>’s vernacular variation and the social discrimination experienced by Eastern Indonesian. The researchers apply qualitative-quantitative method. The data were collected from the distributed online questionnaires which were filled by 41 respondents from Eastern Indonesia (East Nusa Tenggara, Sulawesi, Maluku, Papua). The findings show that there is a diglossic phenomenon between standard <em>Bahasa Indonesia</em> (High variety) and <em>Bahasa Indonesia</em> of Vernacular Eastern Indonesia (Low variety). The unique dialectal characteristics of Eastern Indonesian in <em>Bahasa </em>(phonological, lexical, and morphological) raised the issue of linguistic racism and linguistic privilege. Eastern Indonesian speakers of <em>Bahasa </em>are considered as minority speech community who suffered racism and discrimination. They experienced intimidation from people’s undermining impersonation, underestimation, and exclusion from the dominant speech community. They felt ashamed of their vernacular language identity and tend to imitate dominant accents, such as Javanese or Jakartan Indonesian. This is a serious issue that can increase social disparities and conflict among Indonesians. To solve the problem, the researchers suggest that Indonesian government must introduce <em>Bahasa Indonesia’s variation</em> (including morphological, lexical, and phonological variation from all Indonesian region) in the formal education as the best solution to give societies understanding of linguistic tolerance. </span>
THE SOCIAL FACTOR OF SECOND LANGUAGE ACQUISITION ON ADULT LEARNER
Authors: Samosir Sri Aulia , Daulay Sholihatul Hamidah , Niswa Khairun 
Published: December 2023

<span lang="IN">Second language learning for adults is an activity to help adults in acquiring a second language is done consciously. The learning process for an adult second language is unfounded educator considerations but based on interests learners. E</span><span>d</span><span lang="IN">ucational implications for practical adults is a necessary understanding of characteristics of adult education, principles, methods, and learning techniques second language for people mature. The purpose of this study is to find out the social factor in the classroom influence second language acquisition in adult learners. The researcher found there are classroom situations, namely: Teachers' strategy, students’ personality include (Motivation,</span><span lang="IN"> </span><span lang="IN">introversion/</span><span lang="IN"> </span><span lang="IN">extroversion, self-esteem, inhibition, risk-taking, anxiety), and </span><span>l</span><span lang="IN">earning the English language as a part of a group.</span>
ALIH KODE DAN CAMPUR KODE DALAM INTERAKSI PEMBELAJARAN BAHASA INGGRIS DI FAKULTAS PERTANIAN UNIVERSITAS TRUNOJOYO MADURA
Authors: Susylowati Eka , Alfisuma Meria Zakiyah , Romdlani M.Masqotul Imam 
Published: December 2023

The purpose of the research is to describe code choice and code mixing in the interaction of learning English in Agriculture Faculty University of Trunojoyo Madura. The reseach data included the code switching and code mixing of Agriculture students when learning English in the classroom. The data analysis use a contextual approach of Speaking by Dell Hymes. The result of the research showed that code switching used by the students in the Faculty of Agriculture, namely English and Indonesia, switching codes from English into Indonesia and vice versa, meanwhile code mixing from English into Inonesia, and mixed Indonesia into Javanese, mixed Javanese into English.
APPLICATION OF BAYESIAN REGULARIZATION FOR IMPROVING THE QUALITY OF ELECTRICAL ENERGY IN THE ELECTRICAL SUPPLY SYSTEM
Authors: Yagup Kateryna , Yagup Valery 
Published: December 2023

The possibility of using neural networks in the field of the energy coefficients correction of a power supply system with uneven load in phases is being studied. This need is justified by the fact, that the calculation of the necessary parameters of the symmetry-compensating device was previously based on the Nelder – Mead search optimization method. Search optimization performing is computationally expensive, takes long computation times, and may calculate anomalous values. The article develops the idea of using technology for predicting the parameters of a symmetry-compensating device, based on neural network modeling using Bayesian regularization. For a given set of initial data, the best selected configuration turned out to be a neural network of two layers, implemented in the MATLAB package using the machine learning tool Neural Network Toolbox. The network input parameters are a set of tuples, consisting of load values in each of the three phases of the power supply system, which are resistive-inductive in nature. There are six input quantities in total (load resistance and inductance values in each of the three phases) and all their values are different, which causes current asymmetry in the network and reactive power. The target matrix is formed from tuples, consisting of three values, which are the parameters of the symmetrical compensating device, calculated by the optimization method, in such a way as to compensate reactive power and to balance currents in the network. The number of data tuples, required to train a neural network was determined empirically. During the experiments, the optimal number of neurons in the neural network was also revealed. The use of the generated neural network to calculate the parameters of the symmetry-compensating device determined approximate solutions is comparable in accuracy to the values, found by optimization methods. With the help of the generated neural system, adequate quasi-solutions for calculating the parameters of the symmetry-compensating device were determined, which, in case of calculation, using the optimization method, led to anomalous values, that didn’t optimize the energy coefficients of the power supply system to the required extent. Also, such neuropredictions protect the system from receiving excessive high parameters of symmetry compensating device, which can be obtained with an optimization approach.
Team Approach: Extremity Soft Tissue Sarcoma
Authors: Morris Carol D. , Banks Lauren B. , Fitzhugh Valerie A. , McGill Kevin C. , Deville Curtiland 
Published: December 2023

» Synovial sarcoma is a soft tissue sarcoma that most commonly presents in the extremity in a periarticular location.» As the history and physical examination of patients with synovial sarcoma can overlap considerably with those of patients with non-oncologic orthopedic conditions, it is important that orthopedic surgeons maintain a high level of suspicion when caring for patients with extremity masses.» Soft tissue sarcomas are best treated using a team approach. Early recognition and referral to a multidisciplinary sarcoma team are crucial to ensure the best clinical outcome for the patient.
Contribution of environmental determinants to the risk of developing type 2 diabetes Mellitus in a life-course perspective: a systematic review protocol.
Authors: Mengue Yannick Wilfried , Audate Pierre-Paul , Dubé Jean , Lebel Alexandre 
Published: December 2023

Abstract
Background: Prevention policies of the risk of developing type 2 diabetes mellitus (T2DM) focus solely on individual healthy lifestyle behaviours; while, an increasing number of research recognizes involvement of environmental determinants such as, cultural norms of land management and planning in urban or rural areas, local foodscape, built environment, and neighbourhood deprivation. Precise knowledge of this relationship has therefore become necessary in order to propose prevention strategy that integrates public health and spatial planning. Unfortunately, problems of consistency and synthesis of methods and results in this field of research limit the development of preventive strategies. The aim of this systematic review is to refine knowledge about the relationship between the risk of developing T2DM in adulthood and long-term exposure during childhood or teenage years to its main environmental déterminants.
Methods: This protocol is outlining according the Preferred Reporting Items for Systematic review and Meta-Analysis Protocols tools (PRISMA-P). Three information specialists from Laval University libraries were consulted for the research strategy. Electronic databases (PubMed Central, Embase Elsevier, CINAHL Plus, Web of Science, EBESCO host) and grey literature (theses, dissertations and research reports) will be used for data collection. Based on the Population, Intervention, Comparison, Outcome and Study Design approach, the Covidence application will be used to store the collected data, to perform the selection and extraction. Studies publised from January 1, 2000, to December 31, 2022 in English or French, used quantitative data about individuals aged 18 and over, that report on T2DM (based on medical screening or the use of administrative health data or a concordance study published on self-reported T2DM.), environmental determinants (e.g. cultural norms of land management and planning in urban or rural areas, local foodscape, built environment, and neighbourhood deprivation) and their association (Involving only risk estimators) will be included. Then, study quality and risk of bias will be conducted according to the Effective Public Health Practice Project criteria and ratings.
Discussion: This systematic review will contribute, in this field of research, to refine current knowledge and developing more efficient intersectoral interventions in land use, regional planning and public health.
Systematic review registration:PROSPERO CRD42023392073
Unusually large invasive seeds are spared by rodents in a Patagonian forest
Authors: Campagna Maria Sofia , Barberá Ivan , Morales Juan Manuel , Morán-López Teresa 
Published: December 2023

Abstract

Seed predation by rodents can act as a barrier, limiting the establishment of exotic species. Predation rates of exotic seeds may depend on their attractiveness, determined by their traits and how different they are from natives. Additionally, at the naturalization stage of the invasion process, exotic seeds may escape post-dispersal predation because they are uncommon in the community. To test these ideas, we assessed granivory in a Patagonian forest, where two species with contrasting seed sizes are naturalized. Rubus idaeus seeds are of similar size to native species, whereas Prunus cerasus seeds are four times larger. The relative abundance of their seeds within the landscape is low compared to native seeds. Throughout the fruiting season, we offered seeds from all species present in the community (native and exotics), whenever they were available in the landscape. To consider the effects of vegetation structure on rodent foraging behavior, we offered seeds in areas with or without understory cover. Seed size affected the probability of removal, with rodents preferentially foraging on those of intermediate sizes. Consequently, they strongly avoided large Prunus seeds, but removed Rubus seeds at similar rates to natives. Contrary to our expectations, seed abundance did not affect predation, and hence, rarity did not confer an advantage to exotic seeds. The presence of shrub cover increased 2.3 times the removal rates compared to open areas. Concluding, the dissimilarity in seed size compared to native species and the presence of shrub cover influenced the predation pressure on exotic species within our community.
The Role of Forebody Topology on Aerodynamics and Aeroacoustics Characteristics of Squareback Vehicles using Computational Aeroacoustics (CAA)
Authors: Viswanathan Harish , Chode Kushal Kumar 
Published: December 2023

Abstract
This study investigates the influence of forebody configuration on aerodynamic noise generation and radiation in standard squareback vehicles, employing a hybrid computational aeroacoustics approach. Initially, a widely used standard squareback body is employed to establish grid-independent solutions and validate the applied methodology against previously published experimental data. Six distinct configurations are examined, consisting of three bodies with A-pillars and three without A-pillars. Throughout these configurations, the reference area, length, and height remain consistent, while systematic alterations to the forebody are implemented. The findings reveal that changes in the forebody design exert a substantial influence on both the overall aerodynamics and aeroacoustics performance of the vehicle. Notably, bodies without A-pillars exhibit a significant reduction in downforce compared to their A-pillar counterparts. For all configurations, the flow characteristics around the side-view mirror and the side window exhibit an asymmetrical horseshoe vortex with high-intensity pressure fluctuations, primarily within the confines of this vortex and the mirror wake. Side windows on bodies with A-pillars experience more pronounced pressure fluctuations, rendering these configurations distinctly impactful in terms of radiated noise. However, despite forebody-induced variations in pressure fluctuations impacting the side window and side-view mirror, the fundamental structure of the radiated noise remains relatively consistent. The noise pattern transitions from a cardioid-like shape to a monopole-like pattern as the probing distance from the vehicle increases.
MFNG promotes endothelial-to-mesenchymal transition mediated by the Notch signalling pathway during heart valve development
Authors: Yang Junjie , Wang Zhi , Zhou Yue , Jiang Shiwei , Qin Xiji , Xu Zhikang , Wang Yu , Zuo Mengying , Meng Zhuo , Chen Sun , Wang Qingjie , Wang Jian , Sun Kun 
Published: December 2023

Abstract

A fundamental event in the formation of heart valves involves the transformation of endocardial cells within the outflow tract (OFT) and atrioventricular canal (AVC) cushions through a process known as endothelial-to-mesenchymal transition (EndMT). Aberrant EndMT is a primary cause of congenital valvular malformations. Manic Fringe (MFNG) has been previously associated with cardiovascular development, although its role in heart valve development remains underexplored. In this study, we seek to enhance our understanding of MFNG's involvement in valve formation and its association with EndMT. Staining results of histological section revealed the expression of MFNG in the AVC and OFT during the E9.5-E11.5 period when EndMT takes place. Cellular data demonstrated that MFNG exerts a positive regulatory influence on the EndMT process, promoting endothelial cell migration by enhancing the activity of the Notch signalling pathway. MFNG knockdown mediated by antisense morpholino oligonucleotides(MO) injection caused abnormal heart development in zebrafish. Furthermore, through whole-exome sequencing (WES), we identified a heterozygous MFNG mutation in patients diagnosed with Tetralogy of Fallot-Pulmonary valve stenosis (TOF-PS). Cellular and molecular assays confirmed that this deleterious mutation reduced MFNG expression and hindered the EndMT process. In summary, our study verifies that MFNG plays a role in promoting EndMT mediated by the Notch signalling pathway during the development of heart valves. The MFNG deleterious variant induces MFNG loss of function, potentially elucidating the underlying molecular mechanisms of MFNG's involvement in the pathogenesis of congenital heart valve defects. These observations contribute to the current genetic understanding of congenital heart valve disease and may provide a potential target for prenatal diagnosis and treatment.
Neonicotinoid Insecticides and Their Characteristic Metabolites May Induce High Fasting Blood Glucose and Obesity in Human
Authors: Zhang Mingyue , Zhu Jing , Zheng Pei , Wei Cailv , Li Dehai , Wang Qian , Zhang Hua 
Published: December 2023

Abstract
Neonicotinoid insecticides (NEOs) find widespread application globally as a safeguard for agricultural production. While these pollutants exhibit toxicity towards non-target organisms and pose potential risks to human health, there is a noticeable dearth of studies documenting the adverse effects of neonicotinoid insecticides (NEOs) specifically in humans. In this study, the concentrations of six NEOs and their five metabolites were measured in the blood samples collected from the normal (n = 130) and obesity (n = 130) cohorts in South China. An evaluation was undertaken to examine the associations between the levels of target analytes and either fasting blood glucose (FBG) or the condition of being overweight. Results showed that the NEOs and their metabolites were frequently detected (63%–100%) in both cohorts, with median levels of 0.01–4.32 ng/mL. Discernible gender-related disparities were noted within the blood samples, manifesting as elevated concentrations of the majority of NEOs and their metabolites in females compared to males. In addition, there were positive correlations between the concentrations of IMIeq (imidacloprid equivalent, calculated using the relative potency factors of NEOs and their metabolites) and UF (a metabolite of dinotefuran) with FBG levels (3.28 ng/mL vs. 4.32 ng/mL for UF, and 34.6 ng/mL vs. 40.6 ng/mL for IMIeq). Moreover, significant associations were found between UF [odds ratio = 1.78, 95% confidence interval (CI) = 0.86–4.66, p < 0.01] and IMIeq (odds ratio = 1.66, 95% CI = 0.94–3.56, p < 0.01) concentrations and being overweight. Our findings indicated that human exposure to NEOs and their metabolites may induce high FBG and obesity. This study documented the profile of NEOs and their metabolites in the blood samples from the normal and obesity cohorts in South China for the first time.
Exploration of the importance of viable cells in skin micrograft for wound healing
Authors: Li Yuanjiaozi , Sakamoto Michiharu , Nakano Takashi , Zhao Qiannan , Dong Hang , Sawaragi Eiichi , Yamanaka Hiroki , Tsuge Itaru , Morimoto Naoki 
Published: December 2023

Abstract
Background:
Skin micrograft (MG) has been reported to promote tissue regeneration and is clinically used for intractable wounds. MG contains diverse cells and an extracellular matrix (ECM); however, the importance of the proliferative potential of MG cells for wound healing is not clear. Therefore, we investigated the wound healing-promoting effect of MG, in which the cells were inactivated using several methods.
Methods:
Skin MG was prepared from the skin of C57BL mice using Rigenera protocol, and then four types of MGs were prepared: Fresh-MG, HHP-MG (treated with high hydrostatic pressure of 200MPa for 10 min), LN-MG (treated with liquid nitrogen for 20 min), and Heat-MG (treated heat with 80℃ for 30 min). The outgrowth potential, growth factor content (basic fibroblast growth factor (bFGF), epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF)), and in vitro cell proliferation-promoting potential were examined for each type of MG. For in vivo studies, MG was used to treat murine skin defects. The wound area, neoepithelial length, granulation tissue formation, and newly formed capillaries were evaluated on day 7.
Results:
All types of MGs, except for Heat-MG, contained bFGF, EGF and VEGF, promoted cell proliferation, and accelerated wound closure. In addition, the neoepithelial lengths in the HHP-MG and LN-MG groups were significantly longer than those in the Heat-MG and control groups. The area of granulation tissue, and the number and area of capillaries in the Fresh-MG, HHP-MG, and LN-MG groups were significantly larger than those in the control groups.
Conclusions:
The results confirmed that proliferative cells are not essential for the promotion of wound healing by MG. This effect was attenuated in the Heat-MG group, suggesting that soluble factors, such as growth factors, which are inactivated by heat, play an important role.