bluuebunny/crossref_metadata_2025_split huggingface dataset:
Numerical modelling and experimental investigation into the dehumidification process of a liquid desiccant containing nanoparticles
Authors: Aboosadi Zahra Arab , Shoaib Nader , Esfandiari Nadia , Honarvar Bizhan 
Published: January 2024

Abstract
A cost-effective technology that uses less energy for ventilation and doesn't contain chlorofluorocarbons (CFCs), the liquid desiccant system is seen as a practical alternative. Here, copper oxide nanoparticles were added to the solution in vitro together with a liquid calcium chloride desiccant to study the effectiveness of the dehumidification system. The flow rate and moisture content of the inlet air, as well as the flow rate and temperature of the desiccant solution, were evaluated for their influence on the operation of the dehumidification system. To gauge the degree of air dehumidification caused by the desiccant solution, a device was created and put to the test. MATLAB was used to carry out the mathematical modeling. Copper oxide nanoparticles with a volume percentage of 0.35% and calcium chloride solution with a concentration of 48% by weight were utilized in the studies. The results of soluble dehumidification in both situations with and without nanoparticles showed that the dehumidification rate increased by an average of 5.2% and 6% for both experimental and modeling, respectively, when the nanoparticle content was increased.
Effect of intermittent cutting behavior on grinding force in ultrasonic vibration-assisted grinding of K4002 nickel-based superalloy
Authors: Cao Yang , Zhao Biao , Ding Wenfeng , Wu Jie , Jia Xiaofeng , Zhang Jiong , Das Raj 
Published: January 2024

Abstract
The intermittent cutting behavior, performing as periodic contact phase and separation phase between abrasive grit and workpiece, is an important characteristic in the ultrasonic vibration-assisted grinding (UVAG). This study investigated the effect of intermittent cutting behavior on the grinding force in UVAG. At first, a grinding force model was established by determining the quantity of effective grits and the grinding force of a single grit. Then the influences of ultrasonic vibration phase on the intermittent cutting behavior and grinding force were discussed. Finally, the prediction accuracy of the model was tested through experiments. Results indicated that the quantity of effective grits, unchanged chip thickness and proportion of grits at the sliding, plowing, cutting stages were all changed with the vibration phase. A large unchanged chip thickness and 56% effective grits at the cutting stage were generated at the start of the grits-wheel contact phase. Then, the quantity of effective grits firstly increased to maximum 232 at the vibration phase of 0.5π and then decreased to zero when entering the grits-wheel separation phase. The maximum error of the grinding force model was 15%, indicating that the model was of high accuracy for the force prediction in UVAG.
Techno-Economic Analysis of Biogas Production from Slaughterhouse Biowastes, in Mekelle City, Tigray, Ethiopia
Authors: Belete Fentahun Abebaw , Berhe Goitom Gebreyohannes , Gebreegziabher Tesfaldet Gebregerges , Mekonen Asmelash Gebrekidan , Gebrezgabher Brhanu Teka 
Published: January 2024

Abstract
The utilization of biomass energy such as biogas is currently getting a growing interest by researchers and the final destination of the process is its overall cost, and the profit gained. This study aims on the production of biogas from slaughterhouse biowastes (blood, manure, and rumen content) at optimal conditions, clean-up it and evaluate its feasibility. Calcium oxide and steel wool were used to remove CO2 and H2S respectively.
The methane content of raw biogas and upgraded biogas are 67.20% 0.435% and 82.458% 0.503% respectively. The major fertilizing values (nitrogen, phosphorus, and potassium) content of the digestate were recorded 11,573.00, 392.40, and 426.85 mg/kg respectively. From the economic analysis, urnover ratio, rate of return on investment, payback period, and the production capacity (%) at the break-even point were estimated as 0.22, 12.63%, 4.08 years, and 16.67% respectively. Moreover, a positive value for the net present value (NPV) ($2,949,848.99), as well as 40.37% of the discount cash flow rate of return was obtained. The profitability analysis results indicate that the biogas production process is feasible and acceptable.
Mixed high dielectric constant layers for MOS devices
Authors: Chandra S. V. Jagadeesh , M Sai Jagadeesh , Ch Sai Kiran , B Eswara Rao 
Published: January 2024

Abstract
Tantalum oxide-Ta2O5 mixed zirconium oxide-ZrO2 (TZO) films were deposited on p-silicon substrates using RF magnetron co-sputtering technique. The presence of tantalum, zirconium and oxygen atoms was confirmed by Rutherford Back Scattering analysis with NDF program. XRD spectra revealed that the as-deposited and annealed TZO films were amorphous in nature. It is observed that the accumulation region has become stable after annealing and also observed the reduction in the intensity of the kinks/bumps at depletion region of the C-V curves. The dielectric constant value is also reasonably in good agreement with the reported values at this annealing temperature. The J-V curves revealed that the annealing process effectively reduced the leakage current density upto nano scale range at this lower annealing temperature. The mixed TZO layer showed relatively better thermodynamic and electrical properties after annealing at even lower temperature.
Prenatal anaemia and risk of postpartum haemorrhage: A cohort analysis of data from the Predict-PPH study
Authors: OKUNADE Kehinde S. , ADEJIMI Adebola A. , OLUMODEJI Ayokunle , OLOWE Atinuke , OYEDEJI Olufemi A. , ADEMUYIWA Iyabo Y. , ADELABU Hameed , TOKS-OMAGE Eselobu , OKORO Austin C. , DAVIES Nosimot , ADENEKAN Muisi A. , OJO Temitope , RABIU Kabiru A. , OSHODI Yusuf A. , UGWU Aloy O. , OLOWOSELU FESTUS , AKINMOLA Olukayode O. , OLAMIJULO Joseph A. , OLUWOLE Ayodeji A. 
Published: January 2024

Abstract
Background
Most previous clinical studies investigating the connection between prenatal anaemia and postpartum haemorrhage (PPH) have reported conflicting results.
Objectives
We examined the association between maternal prenatal anaemia and the risk of PPH in a large cohort of healthy pregnant women in five health institutions in Lagos, Southwest Nigeria.
Methods
This was a prospective cohort analysis of data from the Predict-PPH study that was conducted between January and June 2023. The study enrolled n = 1222 healthy pregnant women giving birth in five hospitals in Lagos, Nigeria. The study outcome, WHO-defined PPH, is postpartum blood loss of at least 500 milliliters (mL). We used a multivariable logistic regression model with a backward stepwise conditional approach to examine the association between prenatal anaemia of increasing severity and PPH while adjusting for confounding factors.
Results
Of the 1222 women recruited to the Predict-PPH study between January and June 2023, 1189 (97·3%) had complete outcome data. Up to 570 (46.6%) of the enrolled women had prenatal anaemia while 442 (37.2%) of those with complete follow-up data had WHO-defined PPH. After controlling for potential confounding factors, maternal prenatal anaemia was independently associated with PPH (adjusted odds ratio = 1.37, 95% confidence interval: 1.05–1.79). We also recorded no statistically significant differences in postpartum blood losses between women without anaemia and across the different categories of women affected by anaemia (P = 0.349).
Conclusion
Prenatal anaemia regardless of severity increases the risk of PPH in our study cohort. Our findings have significant policy implications, including the need to lower the prevalence of anaemia in resource-constrained settings like Nigeria by implementing population-level nutritional and educational interventions to improve dietary intake and lower recurrent infections and inflammation among women of reproductive age.
Red-emission, photobiological properties and antimicrobial photodynamic assays using mono-substituted corroles contain carboxylic acid and ester units
Authors: Oliveira Morgana Maciél , Dantas Gabrielle Aguiar , Costa Luiz Antônio Sodré , Santos Roberto Christ Vianna , Iglesias Bernardo A. 
Published: January 2024

Abstract

The mono-substituted corrole derivatives COOH-Cor and COOMe-Cor were obtained by Gryko methodology and characterized by microanalysis. In addition, we investigated experimental photophysical properties (absorption, emission by steady-state and time-resolved fluorescence) in some solvents and TDDFT calculations. Photobiological parameters such as aggregation, photostability and reactive oxygen species generation (ROS) was conducted. In addition, we also evaluated the preliminary antimicrobial photodynamic assays (aPDT) between studied corroles and bacteria strains, by white-light conditions.
The skin circadian clock gene F3 as a potential marker for psoriasis severity and its bidirectional relationship with IL-17 signaling in keratinocytes
Authors: Yuan Xiuqing , Ou Caixin , Li Xinhui , Zhuang Zhe , Chen Yongfeng 
Published: January 2024

Abstract
Background
Psoriasis is an immune-mediated skin disease where the IL-17 signaling pathway plays a crucial role in its development. Chronic circadian rhythm disorder in psoriasis pathogenesis is gaining more attention. The relationship between IL-17 signaling pathway and skin clock genes remains poorly understood.
Methods
GSE121212 with psoriatic lesion and healthy controls was used as exploration cohort for searching analysis. Datasets GSE117239, GSE51440, GSE137218 that contained effective biologics treating psoriasis overtime were applied to validation analysis. Single cell RNA sequencing (scRNA-seq) dataset GSE173706 were used to explore the F3 expression and related pathway activities in single cell levels. Through intersecting with high expression DEGs, F3 was selected as the signature skin circadian gene in psoriasis for further investigation. Functional analyses, including correlation analyses, prediction of transcription factors, protein-protein interaction, single gene GSEA to explore the potential roles of F3. ssGSEA algorithm was performed to uncover the immune related characteristics of psoriasis. We further explored F3 expression in specific cell population in scRNA-seq dataset, besides this, AUCell analysis was performed to explore the pathway activities and the results were further compared between specific cell cluster. Immunohistochemistry experiment, RT-qPCR was used to validate the location and expression of F3, small interfering RNA (siRNA) transfection experiment in HaCaT and transcriptome sequencing analysis were applied to explore the potential function of F3.
Results
F3 was significantly down-regulated in psoriasis and interacted with IL-17 signaling pathway. Low expression of F3 could upregulate the receptor of JAK-STAT signaling, thereby promoting keratinocytes inflammation.
Conclusion
Our research revealed a bidirectional link between the skin circadian gene F3 and the IL-17 signaling pathway in psoriasis, suggesting that F3 may interact with the IL-17 pathway by activating JAK-STAT within keratinocytes and inducing abnormal intracellular inflammation.
Measuring the Impact of Predictive Models on the Software Project: A Cost, Service Time, and Risk Evaluation of a Metric-based Defect Severity Prediction Model
Authors: Bhutamapuram Umamaheswara Sharma , Sadam Ravichandra 
Published: January 2024

Abstract
In a critical software system, the testers have to spend an enormous amount of time and effort maintaining the software due to the continuous occurrence of defects. To reduce the time and effort of a tester, prior works in the literature are limited to using documented defect reports to automatically predict the severity of the defective software modules. In contrast, in this work, we propose a metric-based software defect severity prediction (SDSP) model that is built using a decision-tree incorporated self-training semi-supervised learning approach to classify the severity of the defective software modules. Empirical analysis of the proposed model on the AEEEM datasets suggests using the proposed approach as it successfully assigns suitable severity class labels to the unlabelled modules.
On the other hand, numerous research studies have addressed the methodological aspects of SDSP models, but the gap in estimating the performance of a developed prediction using suitable measures remains unattempt. For this, we propose the risk factor, percent of the saved budget, loss in the saved budget, percent of remaining edits, percent of remaining edits, remaining service time, and gratuitous service time, to interpret the predictions in terms of project objectives. Empirical analysis of the proposed approach shows the benefit of using the proposed measures in addition to the traditional measures.
A novel (2+1)-dimensional Sawada-Kotera type system: multisoliton solution and variable separation solution
Authors: wang jianyong , Yang Yunqing , Tang Xiaoyan , Chen Yong 
Published: January 2024

Abstract
A novel (2+1)-dimensional Sawada-Kotera type system is considered. The existence of three-soliton and four-soliton solutions with constraints on wave numbers is confirmed. Other intriguing solutions, such as the long-range interaction between a line soliton and a y-periodic soliton, are also presented based on the Hirota formalism. By extending the multilinear variable separation approach to the fifth-order nonlinear evolution equation, various localized excitations are introduced, including solitoff, dromion, and an instanton excited by three resonant dromions. In addition to these localized excitations, the general fusion or fission type N-solitary wave solution is obtained, and the resonant Y-shaped soliton and the resonant T-type soliton interaction in shallow water are explored graphically.
Design of the offline test electronics for the nozzle system of proton therapy
Authors: Huang Peng , Yin Zhiguo , Bian Tianjian , Hou Shigang , Guan Fengping , An Shizhong , Wang Yang , Zhang Tianjue , Ji Luyu , Wen Lipeng , Mu Xueer 
Published: January 2024

Abstract
A set of nozzle equipment for proton therapy is now being developed at China Institute of Atomic Energy. To facilitate the off-line commissioning of the whole equipment, a set of ionization chamber signal generation system, the test electronics, is designed. The system uses ZYNQ SoC as the main control unit and outputs the beam dose analog signal through DAC8532. The dual SPDT analog switch, DG636, is used to simulate the beam position signals according to Gaussian distribution. The results show that the system can simulate the beam position, dose, and other related analog signals generated by the proton beam when passing through the ionization chamber. Moreover, the accuracy of the simulated beam position is within ± 0.33mm, and the accuracy of the simulated dose signal is within ± 1%. At the same time, it can output analog signals representing environmental parameters. The test electronics meets the design requirements, which can be used to commission the nozzle system as well as the treatment control system without the proton beam.
Annexin-A1 tripeptide alleviates lung ischemia-reperfusion injury by promoting lung autophagy in rats
Authors: Luo Junli , He Yunzi , Li Jian , Wu Hanhua , Zhang Hong , dou xuejiao 
Published: January 2024

Abstract
Research on the mechanism and protective measures of lung injury caused by CPB has attracted extensive attention. But the exact mechanism is still being explored. This study explored the role of autophagy in CPB lung injury by establishing the left lung ischemia-reperfusion injury model of rats and observing the relationship between CPB lung injury and autophagy. The effects of exogenous membrane tripeptide (AnxA1sp) on lung injury and autophagy in rats were investigated. Compared with the control group, the expressions of autophagy bodies and autophagy-related proteins in the lung tissue of rats after CPB were increased in the model group. With the aggravation of lung injury, autophagy was significantly increased and the degradation of autophagy was blocked. Autophagy was involved in the occurrence and development of CPB lung injury. In the rat model group of AnxA1-/-, lack of AnxA1 can cause insufficient autophagy and aggravated lung injury in CPB rats. The addition of exogenous AnxA1sp can reduce lung I/R injury in CPB rats, activate lung autophagy, promote autophagy flow, reduce the release of lung inflammatory factors, reduce lung pathological injury, and improve lung function. In conclusion, regulating the autophagy of lung tissue can produce a lung protection effect.
Post-traumatic Stress Symptoms in Trauma- exposed Children and Adolescents on the Qinghai-Tibet Plateau: Associations with Prosocial Behavior and Resilience
Authors: Xiao Fei , Eli Buzohre , Chen Yaru , Gong Pu , Huang Yijin , Lv Meixuan , Liu Zhengkui 
Published: January 2024

Abstract
High altitude has always been associated with a higher risk of trauma exposure. However, little is known about the stress-related symptoms and associated factors among trauma-exposed children and adolescents in high plateau areas. This study aimed to investigate the severity of post-traumatic stress symptoms (PTSS) and the associated factors, namely prosocial behavior and resilience, among trauma-exposed children and adolescents in the Qinghai-Tibet Plateau. A cross-sectional study was conducted among 14,428 primary and middle school students and 2,297 trauma-exposed children and adolescents aged 10–19 were included in the final analysis. The PTSS, prosocial behavior, and resilience were measured via three self-reported questionnaires: the Child Post-Traumatic Stress Symptom Scale (CPSS), the Prosocial Behavior Subscale of the Strength and Difficulties Questionnaire (SDQ), and the short version of the Connor-Davidson Resilience Scale (CD-RISC), respectively. A structural equation model was constructed for data analysis. Approximately 70% of trauma-exposed children and adolescents had experienced PTSS, suggesting a probable presence of post-traumatic stress disorder (PTSD). Higher levels of prosocial behavior were significantly associated with fewer PTSS. Furthermore, resilience significantly mediated the relationship between prosocial behavior and PTSS with an indirect effect of − 0.28. The results highlight the severity of PTSS among trauma-exposed youth in high plateau areas. The findings also indicate that prosocial behavior in children and adolescents is a protective factor against the negative outcome of trauma exposure, suggesting that improving prosociality could be an intervention to promote mental health.
Integrative Analysis of Differentially Expressed Genes in Time-Course Multi-Omics Data withMINT-DE
Authors: Xue Hao , Delbare Sofie , Wells Martin , Basu Sumanta , Clark Andrew 
Published: January 2024

Abstract

Background: Time-course multi-omics experiments have been highly informative for obtaining a comprehensive understanding of the dynamic relationships between molecules in a biological process, especially if the different profiles are obtained from the same samples. A fundamental step in analyzing time-course multi-omics data involves selecting a short list of genes or gene regions (''sites'') that warrant further study. Two important criteria for site selection are the magnitude of change and the temporal dynamic consistency. However, existing methods only consider one of these criteria, while neglecting the other.
Results: In our study, we propose a framework called MINT-DE (Multi-omics INtegration of Time-course for Diffierential Expression analysis) to address this limitation. MINT-DE is capable of selecting sites based on summarized measures of both aforementioned aspects. We calculate evidence measures assessing the extent of differential expression for each assay and for the dynamical similarity across assays. Then based on the summary of the evidence assessment measures, sites are ranked. %To evaluate the performance of MINT-DE, we apply it to analyze a time-course multi-omics dataset of \textit{Drosophila} development. We compare the selection obtained from MINT-DE with those obtained from other existing methods. The analysis reveal that MINT-DE is able to identify differentially expressed time-course pairs with the highest correlations. Their corresponding genes are significantly enriched for known biological functions, as measured by gene-gene interaction networks and the Gene Ontology enrichment.
Conclusions: These findings suggest the effectiveness of MINT-DE in selecting sites that are both differentially expressed within at least one assay and temporally related across assays. This highlights the potential of MINT-DE to identify biologically important sites for downstream analysis and provide a complementarity of sites that is neglected by existing methods.
Domestic Violence among Female Psychiatric Patients in Ain Shams University Hospitals. An Egyptian Study
Authors: Abdel-Samei Afaf Mohammad Abdel-Samei , Hashem Reem El-Sayed Mohamed Hashem , Mohammad Doaa Ibrahim Eid Mohammad , Serag Rehab Serag 
Published: January 2024

Abstract
Background: One of the most prevalent types of interpersonal violence worldwide is domestic violence. It is defined as "any incident of threatening behavior, violence or abuse (psychological, physical, sexual, financial or emotional) between adults who are or have been an intimate partner or family member, regardless of gender or sexuality.
Objective: To assess the rate of domestic violence in a sample of female psychiatric patients. To evaluate the correlation between clinical diagnosis and sociodemographic factors and domestic violence.
Patients and Methods: 200 married female patients attending outpatient clinic at Okasha Institute of Psychiatry, Ain Shams University hospitals. We collected the socio-demographic and clinical data for the study participants, SCID I was used to confirm the DSM IV diagnosis, and CAS was used to assess exposure to abuse and frequency over the past year.
Results: The study showed an alarmingly high rate of 86.5% of sample patients being exposed to domestic violence. The majority of patients were exposed to emotional abuse (85.5%), then physical abuse (67%), followed by exposure to severe combined abuse (65.5%) and the least exposure was to harassment (45.5%). Schizophrenia and substance use disorder showed the highest correlation with abuse, while OCD had the lowest.
Conclusion: The study exposes an alarming prevalence of intimate partner violence (IPV) among psychiatric patients. These findings highlight the need for targeted interventions to address IPV in vulnerable psychiatric populations.
Genetic lineage traces the differentiation fate of epicardial cells during heart development
Authors: Lu FR , Yang xiaojie 
Published: January 2024

Abstract
Objective The genetic lineage tracing method was used to examine the epithelial-mesenchymal transition (EMT) process and the contribution of epicardial cells to mesenchymal cells at various stages of fetal heart development.
Methods In Wt1-CreER;R26-tdTomato transgenic mice, tamoxifen was utilized to promote the tagging of epicardial cells with tdTomato fluorescence at E10. At E11.5, E12.5, and E16.5, embryonic hearts were harvested and photographed using confocal fluorescence microscopy and stereomicroscopy.
Results According to the findings, the tdTomato+ cells at E11.5 were still in the epicardium and had not yet moved into the myocardium. Epicardial cells began to separate from the epicardium and give rise to epicardial-derived cells at embryonic day 12.5 (E12.5). On the valve primordium, fibroblasts generated from epicardium have been found.By E16.5, many epicardial cells had moved into the myocardium and formed fibroblasts, mesenchymal cells, vascular smooth muscle cells, as well as migrated into the ventricular septum and valves, contributing to their growth and creation.
Conclusions The contribution of epicardial cells to mesenchymal cells during development is shown by genetic lineage tracing, opening up possibilities and offering references for creating relevant treatment approaches based on epicardial cells.