bluuebunny/crossref_metadata_2025_split huggingface dataset:
Different Configurations of Neoaortoiliac System Operation: An Institutional Experience
Authors: Indira Nandam Srikantiya , Mahapatra Sandeep , Arumalla Anusha , Paul Roma , Gokavarapu Siva Kumar , Vempati Apoorva , Mukkamala Harichandana Pragna Sree , Palepu Sneha , Venkatesh Narra Naga , Sai Gorentla Narasimha 
Published: January 2024

Abstract

Background:
Mycotic aortic aneurysm of the abdominal aorta is a rare entity. Repair of infected aneurysms is challenging because of the deleterious consequences of the usage of prosthetic material as an arterial conduit with limited availability of autogenous grafts. Aortic graft infection is one of the most morbid complications in vascular surgery. The main objective in treating aortic graft infection is to remove the infected graft material, thoroughly debride, and re-establish the vascular continuity. Neo-Aortoiliac system operation utilizes the femoropopliteal vein in various configurations, depending on the extent of infection and the availability of the conduit.

Aim:
This article aims to report our experience of various configurations of Neo aortoiliac system operation and various conduits used along with femoropopliteal vein, when the femoropoliteal vein is inadequate.

Materials and Methods:
The study was performed in a single tertiary care center. Between January 2022 and June 2023, 4 cases of Neo aortoiliac system operation were performed. The demographics, clinical presentation, operative data, and postoperative outcomes were subsequently collected and analysed.

Results:
3 out 4 patients of Neo-Aortoiliac system operation survived, one patient had Major Adverse Limb Event and one patient succumbed to death due to sepsis.
Mycotic Aortic Arch Aneurysms: Open versus Endovascular Management – An Institutional Experience
Authors: Sun Neelamjingbha , Pandey Ashutosh Kumar , Manchikanti Sriram , Gupta Aditya , Rajeev Akash , Muniswamy Sandeep , Jain Prashant , Pitchai Shivanesan 
Published: January 2024

Abstract

Background:
Mycotic aortic aneurysms are rare disorders, affecting patients with co-morbidities, and associated with a high risk of aneurysm expansion, rupture, and sepsis.

Aims and Objectives:
In this study, we present our experience on the management of patients with mycotic arch aneurysms.

Materials and Methods:
From January 2020 till July 2023, eight patients were admitted in our hospital for management of mycotic aortic arch aneurysm. On a case-to-case basis, the management was selected for each patient and consent was taken for the same.

Results:
Four patients underwent open repair and four endovascular repair, out of which three underwent hybrid arch repair. While only one patient in the open group expired in the immediate postoperative period due to sepsis, the remaining patients have been on follow-up for 1month-1year. There was no mortality in the immediate post TEVAR period. However, three of the patients who underwent TEVAR required re-admissions and re-intervention, with one patient developing aorto-esophageal fistula. Two of these patients expired in a span of 3months-1.5years post TEVAR.

Conclusion:
In patients with mycotic arch aneurysm, open surgical repair should be the modality of choice in fit surgical patients and endovascular management can be used as a bridge therapy, keeping in mind the risks of residual infection in the aorta which can lead to re-interventions and re-admissions.
Compassion satisfaction, burnout, and secondary traumatic stress among nurses after the second wave of the COVID-19 pandemic
Authors: Dixit Priyanshi , Srivastava Saumya P. , Tiwari Surya Kant , Chauhan Soni , Bishnoi Ravi 
Published: January 2024

Background:
Nurses frequently experience compassion fatigue and burnout, which impact their personal lives and patient care. The COVID-19 pandemic additionally caused stress, uncertainty, and fear of death among healthcare professionals.

Aim:
To assess professional quality of life (ProQoL) among nurses after the second wave of the COVID-19 pandemic.

Material and Methods:
A web-based cross-sectional study was conducted among 203 nurses using a purposive sampling technique in the month of September to December 2021. Data were collected using a self-administered ProQoL scale version 5.

Statistical Analysis:
Descriptive and inferential statistics were used. Kolmogorov–Smirnov test, Mann–Whitney U, and Kruskal–Wallis H test were used. Bivariate correlations were used to correlate the main variables. Multiple linear regression analysis was also performed.

Results:
The majority of the nurses reported a moderate level of compassion satisfaction (CS) (62.6%), burnout (BO) (66.0%), and secondary traumatic stress (STS) (63.1%). Residence and education emerged as a factor whether the nurses experienced BO or STS, respectively. Additionally, CS negatively correlated with BO (r = -0.732: P < 0.001) and STS (r = -0.141: p-0.04).

Conclusions:
The majority of the nurses experienced moderate levels of CS, BO, and STS after the second wave of the COVID-19 crisis and nurse patient–ratio emerged as a significant factor to predict CS, BO, or STS. Hence, effective measures need to be implemented by hospital administration to enhance the nurses’ satisfaction and reduce fatigue and burnout.
Prevalence of generalized anxiety disorder among patients attending medicine outpatient department in a tertiary care center: A cross-sectional study
Authors: Veloumourougane Gokoul , Ramamurthy Parthasarathy , Thilakan Pradeep , Raghuraman Preethy , Vimal Joseph 
Published: January 2024

Background:
Generalized anxiety disorder is commonly underdiagnosed and undertreated in medical settings.

Aim:
The objectives of this study were to determine the prevalence and correlates of generalized anxiety disorder among patients presenting to medicine outpatient department in a tertiary care centre.

Materials and Methods:
A cross-sectional observational study was conducted among the patients visiting the outpatient department of General Medicine in a tertiary care teaching hospital. Sociodemographic and clinical parameters were collected using a structured pro forma. All patients were administered Generalized Anxiety Disorder-7 (GAD-7) to screen for the presence of generalized anxiety disorder. Patients who score 10 or more underwent a semi-structured evaluation using a generalized anxiety disorder module of Structured Clinical Interview for DSM-IV Axis I disorders.

Results:
Two hundred and fifty patients were recruited for the study. The mean age of the participants was 40.66 ± 12.8 years. More than one-fourth of them had diabetes mellitus and about one-fifth of the participants had systemic hypertension and hypothyroidism. Thirty five (14%) participants screened positive on GAD-7 scale. On detailed evaluation using SCID-I, 19 (7.6%) participants were confirmed to have a generalized anxiety disorder. Female gender was associated with the presence of GAD.

Conclusion:
One in thirteen patients presenting to the medicine outpatient department were found to have generalized anxiety disorder. Female patients had a greater prevalence of generalized anxiety disorder compared to male patients.
Evaluation of tumor-educated platelet long non-coding RNAs (lncRNAs) as potential diagnostic biomarkers for colorectal cancer
Authors: Tabaeian Seidamir Pasha , Eshkiki Zahra Shokati , Dana Fatemeh , Fayyaz Farimah , Baniasadi Mansoureh , Agah Shahram , Masoodi Mohsen , Safari Elahe , Sedaghat Meghdad , Abedini Paria , Akbari Abolfazl 
Published: January 2024

ABSTRACT

Introduction:
Cancer-derived circulating components are increasingly considered as candidate sources for non-invasive diagnostic biomarkers. This study aimed to investigate the expression of tumor-educated platelet (TEP) long non-coding RNAs (lncRNAs) in colorectal cancer (CRC) patients and determine whether it could be served as a potential tool for CRC diagnosis.

Materials and Methods:
Relative quantitative real-time PCR (qRT-PCR) was used to detect the expression levels of three cancer-related platelet-derived lncRNAs CCAT1, HOTTIP, and XIST in 75 CRC patients and 42 healthy controls. Quantitative data were analyzed by SPSS (IBM Corp., Armonk, NY, USA) for comparison of cancer and non-cancer individuals. The receiver operating characteristic (ROC) curve analysis was further performed to assess the diagnostic values of lncRNAs within the CRC patients.

Results:
The expression levels of lncRNAs colon cancer associated transcript 1 (CCAT1) (P = 0.006) and HOXA transcript at the distal tip (HOTTIP) (P = 0.049), but not X-inactive specific transcript (XIST) (P = 0.12), were significantly upregulated in CRC patients compared to healthy individuals. However, there were no significant correlations between platelet lncRNAs and clinicopathological characteristics, including sex, age, tumor location, differentiation, and size (all at P > 0.05). The area under the ROC curve (AUC) of the lncRNA CCAT1 was 0.61 (sensitivity, 71%; specificity, 50%).

Conclusion:
TEP lncRNA CCAT1 is detectable in the circulation of CRC patients and could be considered as a potential diagnostic biomarker.
Durable response to docetaxel in a case of primary seminal vesicle adenocarcinoma with zinner syndrome
Authors: Fatima Sheereen , Shaikh Imran N. , Athikari Nevitha 
Published: January 2024

ABSTRACT
Primary adenocarcinoma of the seminal vesicles is a rare tumor. Congenital seminal vesicle cysts are often associated with unilateral renal dysgenesis or agenesis (Zinner syndrome). Zinner syndrome is a rare congenital malformation represented by a group of characteristics: ipsilateral renal agenesis, ejaculatory duct obstruction, and seminal vesicle cyst. There have been 214 cases in the literature with abdominal pain and lower urinary tract symptoms as the most common presentation. Most cases are diagnosed incidentally. We report a case of a 39-year-old male presenting with recurrent hematuria for 12 years, diagnosed as metastatic primary clear cell adenocarcinoma of seminal vesicle with Zinner syndrome. He was managed symptomatically with radiation therapy, hormonal therapy, and palliative chemotherapy. He is living with a well-controlled disease at present.
Cardiac migration of an implanted hepatic fiducial marker used for stereotactic body radiation therapy - A case report
Authors: Soliman Youstina , Antony Febin , Vivian Mark , Venkatraman Sankar , Nashed Maged 
Published: January 2024

ABSTRACT
Stereotactic body radiation therapy (SBRT) has been increasingly used to treat liver malignancies because large doses of radiation can be delivered precisely to the target with a rapid dose falloff. Real-time tracking of implanted fiducial markers (FMs), combined with respiratory gating, further improves the accuracy of treatment delivery and reduces the dose to critical structures. There have been reports of migration of the FMs after implantation for SBRT. Calypso beacons, which use the electromagnetic wave reflections for the image guidance, have recently been used for image-guided liver SBRT. In the literature, there are no reports on the migration of Calypso beacons to the heart after implantation in the liver. In this report, we detail the first case of such migration. Respiratory-gated SBRT guided by the Calypso system was planned for our patient, who developed liver metastases in segments 6 and 5/4B shortly after the completion of radical chemoradiotherapy for anal squamous cell carcinoma. One of the three Calypso beacons inserted in the liver under computed tomography (CT) guidance was found to have migrated to the right ventricle, as seen in CT simulation images. SBRT was delivered with respiratory gating using the remaining two beacons. A fluoroscopic imaging performed during treatment confirmed the migrated marker to the right ventricle. Patient denied any cardiac symptoms and SBRT were delivered uneventfully. Ten months later, the patient died of disease progression.
Comparative evaluation of quality of life in oral cancer patients undergoing 3-dimensional conformal radiation therapy with or without concomitant chemotherapy – A longitudinal study
Authors: Parate Prajakta M. , Mahajan Aarti M. , Prakash Nilima , Pradeep GL , Harnekar Shirin H. , Sadhwani Vaishali A. 
Published: January 2024

ABSTRACT

Objectives:
To assess and compare the quality of life (QOL) in Oral Cancer patients undergoing 3-DCRT with or without concomitant Chemotherapy at three different time intervals.

Materials and Methods:
This unicentric longitudinal study included 50 patients of oral cancer undergoing 3-DCRT with or without concomitant chemotherapy. QOL was recorded using the EORTC H and N 35 Questionnaire at baseline, end of treatment (EOT), and 3 months after treatment.

Results:
Maximum deterioration of most QOL domains were noted at End of treatment (EOT) in all the patients. A highly statistically significant difference was noted between different time intervals with the highest scores noted at the EOT (P < 0.01). There was a statistically significant difference in patients undergoing 3DCRT with chemotherapy when compared to those with 3DCRT without chemotherapy (P < 0.05).

Conclusion:
There is substantial deterioration in QOL at the EOT after head–neck irradiation by 3-DCRT with or without concomitant Chemotherapy although it gradually improves over time. However, 3DCRT results in clinically meaningful and statistically better QOL scores at 3 months after treatment compared to baseline and EOT.
Translation and pilot validation of Hindi, Marathi, and Bangla translation of quality of life EORTC module (QLQ-SH-22) for assessing sexual health-related quality of life
Authors: Krishnatry Rahul , Rane Devankshi , Krishnamurthy Revathy , Pawar Purva , Chakraborty Debanjan , Gaikwad Utpal , Ghosh Suman , Datta Debanjali , Anup Akanksha , Das Sayan , Ambre Tejaswi , Makwana Divya , Gudi Shivkumar , Engineer Reena 
Published: January 2024

ABSTRACT

Aim:
To translate and validate the European Organization for Research and Treatment for Cancer (EORTC) module for assessing the sexual health-related quality of life in cancer patients (QLQ-SH22), in Hindi, Marathi, and Bangla languages for clinical use.

Methods and Results:
The EORTC QLQ-SH-22 was translated into Hindi, Marathi, and Bangla by adopting standard guidelines given by EORTC. Initially, the original questionnaire was forward translated by two separate translators, followed by the reconciliation of the forward translations by a third person. This was followed by two back translations of the reconciled version into English by two other translators. These back-translated questions were then compared with the original EORTC questions for accuracy, and once acceptable, a preliminary questionnaire was prepared in all three languages. These questionnaires were then pilot tested with 30 patients (10 for each language) diagnosed with any of the cancers in the pelvic region who are expected to be at risk of sexual quality of life due to tumor or treatment like pelvic radiotherapy. Participated patients had never seen or filled the questionnaire before, each patient was interviewed after filling the questionnaire for difficulty in answering, confusion, difficulty understanding, or if any of the questions were upsetting and if patients would have asked the question differently.

Results:
None of the patients reported any changes or suggestions for all the three translations. All the translated questionnaires were well understood by all the patients. Pilot testing reports were sent to EORTC. After reviewing the entire report of Hindi, Marathi, and Bangla translations, these questionnaires were approved by the EORTC translation unit. The questionnaires are reliable with Cronbach’s α for Hindi, Marathi, and Bangla being 0.69, 0.66, and 0.86, respectively.

Conclusion:
The final Hindi, Marathi, and Bangla translations of SH 22 have been approved by the EORTC and can be used to assess the sexual health of cancer patients in routine oncology practices and/or clinical studies.
Compressive Intrapericardial Hematoma Following Thoracotomy to Seal Coronary Artery Perforation
Authors: Shukla Madhu , Mohan Jagdish Chander 
Published: January 2024

Abstract
A 68-year-old male developed cardiac tamponade secondary to coronary artery perforation following percutaneous coronary artery intervention. He underwent thoracotomy to seal the perforation of the acute marginal branch of the right coronary artery. Following sealing of perforation with application of cyanoacrylate to the right atrioventricular groove, the patient remained stable with minimal pericardial effusion for 1 month and later developed a large (6 cm × 5 cm) intrapericardial hematoma compressing the right ventricular inflow with intermittent fever. The patient declined repeat surgery and showed some regression of hematoma and a decrease in trans-tricuspid pressure gradients with colchicine after 1 month. The case is reported for its rarity with a review of literature.
Claustros académicos y su contribución con la calidad de los doctorados en educación en Chile
Authors: Hidalgo Gutiérrez Paulina , Molina Díaz Cristian 
Published: January 2024

La Comisión Nacional de Investigación en Ciencia y Tecnología (CONICYT) en los noventa, hoy llamada Agencia Nacional de Investigación y Desarrollo (ANID), comenzó a trabajar con el objetivo de regular la creación y validación de los programas de postgrado en Chile, y en específico en el cuerpo académico. El propósito de este trabajo es identificar la composición del perfil de los académicos del claustro y su contribución con la calidad de los doctorados en Educación en Chile. Se realizó un análisis descriptivo, de la información obtenida desde la base de datos Sistema de Información de Educación Superior (SIES) del Ministerio de Educación y un análisis cualitativo de los claustros con base cienciométrico de los programas. En el período 2017-2022 se desarrollaron doce programas de Doctorado en Educación. Los programas acreditados pertenecen a universidades del Consejo de Rectores (CRUCH) y poseen claustros con líneas de investigación a fines con las líneas de investigación de los programas en estudio, otorgando sostenibilidad de calidad a los doctorados, no así los programas no acreditados. Se concluye que la acreditación de Doctorados en Educación depende de un cuerpo académico de calidad, con líneas de investigación definidas alineadas con las investigaciones de dichos programas, y sus consecuencias son tener un programa de Postgrado de calidad y niveles mínimos de acreditación.
The paradox of spironolactone: A heart failure treatment with potentially harmful effects
Authors: Muhammad Roshan  , Muhammad Ahmad Nadeem  , Sahar Imran Khalfay  
Published: January 2024

Madam,
Heart failure (HF) is a multifaceted clinical syndrome arising from a functional or structural cardiac condition that hampers the adequate filling or expulsion of blood into the systemic circulation. It is estimated that heart failure affects around 26 million people globally and significantly adds to healthcare expenditures on a worldwide scale1. Furthermore, in 2016, approximately 16 percent of deaths in Pakistan were due to heart related disorders. This number grew to 29 percent in 20222. HF can greatly diminish the functional capability of a patient and heighten the risk of mortality. Therefore, it is essential to accurately diagnose and proficiently manage this condition to improve the quality of life of the patient.
Spironolactone, the first mineralocorticoid receptor antagonist (MRA) to be developed, is prescribed for the management of hypertension, primary hyperaldosteronism, and peripheral oedema linked to cardiac failure3. When HF occurs and cardiac output decreases, it stimulates the renin-angiotensin-aldosterone system (RAAS) which in turn causes salt and water reabsorption and thus increases venous return to the heart which further contributes to congestive heart failure and heart fails to pump the additional fluid and pooling occurs. Here MRAs are very affective as they inhibit the function of aldosterone and hence fluid retention does not occur.
Unfortunately, the beneficial effects of spironolactone do not occur without substantial adverse effects. Firstly, spironolactone is associated with sexual adverse events due to its affinity for androgen and progesterone receptors. There have been reports of male patients experiencing gynecomastia and breast pain. Secondly, spironolactone has been classified as potassium sparing diuretic hence hyperkalemia (defined as serum K+ > 5.5 mEq/L) is a common side effect3. Hyperkalemia can manifest as muscle weakness or paralysis, metabolic acidosis, cardiac conduction abnormalities, and life-threatening cardiac arrhythmias4. These cardiac arrythmias can have serious consequences, including cardiac arrest and stroke.
In conclusion heart failure, if not treated immediately, can be fatal. Spironolactone is a drug used for management of heart failure; however, it has some detrimental effects on the cardiovascular system such as development of serious cardiac arrythmias. Hyperkalemia, due to potassium sparing nature of MRAs, is the primary cause of these life-threatening effects thus it is recommended to assess serum potassium levels and renal function of a patient with heart failure before prescribing spironolactone. Moreover, patients who are being treated with spironolactone should be periodically monitored to prevent any casualty.
Kesejahteraan Nelayan Tangkap Dalam Perspektif Ekonomi Islam Di Kecamatan Banggae Kabupaten Majene
Authors: Atirah  
Published: January 2024

Kesejahteraan hingga saat ini masih merupakan defenisi semu yang masih terus dipertanyakan kebenarannya. Konsep sejahterah selalu dirasakan berbeda beda dalam tiap kalangan dengan berbagai indicator yang dipertimbangkan setiap individu maupun keluarga, dikarenakan beberapa keadaan konsep kesejahteraan disetiap jenis pekerjaan dan kondisi keluarga dinyatakan berbeda beda. Kesejahteraan untuk masyarakat nelayan, Pembagian tingkatan Nelayan menjadi beberapa tingkatan juga memberikan pemahaman konsep kesejahteraan yang berbeda. penelitian ini adalah penelitian Kualitatif Deskriptif dengan melakukan analisis Kesejahteraan Nelayan Tangkap dilihat dalam perspektif Ekonomi Syariah. Penelitian ini berlokasi di Kec. Banggae Kab. Majene Kel.Totoli dengan subjek penelitian Pada Nelayan Tangkap . Metode Pengumpulan data dalam penelitian ini adalah Wawancara dan Dokumentasi. Hasil penelitian menunjukkan bahwa nelayan merupakan anggota dari kapal bodi yang setiap berlayar mencari ikan mereka akan beranggotakan beberapa orang dan akan dimodali oleh seorang yang dinamakan Punggawa. Kesejahteran spiritual, kesejahteraan materil dan kesejahteraan moral dilihat dari aktivitas nelayan dalam menjalankan profesinya serta kerja sama yang ditunjukkan hingga pembagian hasil melaut hingga menanggapi dan beradaptasi dengan kondisi dan keadaan ketika tidak dapat turun melaut dikarenakan cuaca.
HUBUNGAN STATUS GIZI DENGAN SIKLUS MENSTRUASI PADA REMAJA PUTRI DI SMA MUHAMMADIYAH 7 YOGYAKARTA
Authors: Yani Windi Lusi , Rahayu Budi 
Published: January 2024

ABSTRAK

Masa remaja ialah perubahan berasal kanak-kanak sampai dewasa dilihat dari perubahan fisik, psikis serta psikososial, Masa remaja ditandai dengan datangnya menstruasi pertama. Menstruasi akan mengalami siklus yang tidak teratur di pertama masa reproduksi. Asupan nutrisi yang tidak baik berdampak pada penurunan fungsi reproduksi. Mekanisme status gizi dengan siklus menstruasi dapat mempengaruhi pola siklus menstruasi, baik pada wanita dengan gizi kurang maupun gizi lebih. Teratur tidaknya siklus menstruasi berkaitan dengan hormon terutama pada hormon seksual, yaitu progesterone, estrogen, LH dan FSH. Tujuan Mengetahui hubungan status gizi dengan siklus menstruasi. Metode penelitian yang digunakan adalah analitik, dengan desain pendekatan penelitian Deskriptif Retrospektif. Penelitian ini menggunakan sampel 68 remaja putri. Analisis data menggunakan uji statistik Chi-Square. Hasil Penelitian Berdasarkan uji statistik Chi-Square diperoleh hasil dengan nilai signifikan didapatkan p value = 0,005 (p< 0.05). Kesimpulan Ada Hubungan Status Gizi dengan Siklus Menstruasi dengan hasil hubungan yang kuat.
Kata Kunci: Status Gizi, IMT, Gangguan Siklus Menstruasi, Siklus Menstruasi.