bluuebunny/crossref_metadata_2025_split huggingface dataset:
The prognostic significance of XL DLEU/LAMP (13q14 deletion) in CCL patients: a cross section study
Authors: Ammar Hadi Farah , Shakir Al-Dubaisi Suad , Salim Al-Mudallal Subih 
Published: January 2024

Background: Many cytogenetic abnormalities were detected in CLL, one of them. Deletion of 13q14 region which is found in more than 50% of CLL patient. 13q deletion is the most common cytogenetic abnormality detected by fluorescence in situ hybridization (FISH) and has historically been associated with good prognosis. During the last years, several studies have revealed some insights in the candidate genes located at 13 q that could be responsible for CLL pathogenesis,as well as in the prognostic heterogeneity of 13q- deleted patients.
Aim of the study: evaluation of the prognostic value of 13q chromosome deletion in patients with CLL in correlation to complete blood picture, absolute lymphocyte count, prolymphocyte count and modified Rai staging.
Patients and method: This cross-sectional study was conducted on thirty adult with newly diagnosed and Denovo B-CLL patients tested for the expression of 13q deletion using Fluorescence Insitu Hybridization, from March 2018 to July 2018 and the diagnosis was document on the morphology and immunephenotyping of the peripheral blood sample using a four-color flow cytometer in the Nursing Home Hospital / flow cytometry department of the Medical City in Baghdad.
Results: XL DLEU/LAMP (13q14 deletion) was seen in 7 (23.3 %). 13q14 deletion was not significantly correlated to age, gender, splenomegaly, lymphadenopathy or hepatomegaly. There was highly significant difference in mean Hb between CLL patients with positive 13q14 deletion and those with no deletion (P = 0.001), being higher in patients with positive 13q14 deletion than those without deletion, 12.96 ± 1.41 g/dl versus 10.14 ±1.74 g/dl, respectively. In addition, all CLL patients with positive 13q14 deletion were free of anemia, whereas anemia (Hb < 11 g/dl) was seen in 17 (73.9 %) of patients with no deletion; the variation in 13q14 deletion according to anemia was highly significant (P = 0.001).
Conclusion: indirectly, one can suppose that chromosome 13q.14 deletion carry good prognosis in CLL patients; however, it appears better to link such deletion to survival rate in order to get better idea about its prognostic significance.
Association between low serum vitamin D level and retinal venous occlusion at lbn- Alhaitham eye teaching hospital
Authors: Abdul Zahraa Muttar Afrah , Majied Hamiedd Furkaan 
Published: January 2024

Background: Retinal vein occlusion is the second most common cause of sudden vision loss from retinal vascular diseases, following diabetic retinopathy. The role of vitamin D in maintaining the vascular system is now being increasingly understood and the effect of Vitamin D deficiency on vascular endothelium could possibly have some role to play in the causation of retinal vein occlusion.
Objective:To estimate serum vitamin D3 (25 OH D) level in patients of retinal vein occlusion and compare it with age and gender -matched controls.
Subject and methods: This study is a hospital-based, case-control study conducted between October 2017 and February 2018 and included 35 cases of retinal venous occlusion (14 cases of branch retinal vein occlusion and 21 cases of central retinal vein occlusion, no cases of hemiretinal venous occlusion) with onset less than three months were enrolled. These cases were compared with 35 age and gender matched attendants of patients as controls, as they had comparable dietary and socioeconomic condition. Serum vitamin D3 (25 OH D) was done for cases and control group. Student’s t test was used to assess the significance of differences in mean vitamin D levels, while chi square test was used to assess the significance of association and comparison of frequencies in categorical variables. Level of significance of ? 0.05 considered as cutoff for significant difference or association.
Results: the mean serum vitamin D level was significantly lower in retinal vein occlusion group than controls, (14.21 ± 5.19) ng/ml and (22.70 ± 4.43) ng/ml, respectively, on the other hand, vitamin D level in these cases ranged (7 – 25.80) ng/ml which was also lower than that in controls (range: 14.89 – 33.60)ng/ml, the difference in mean vitamin D level between groups was highly significant (P< 0.001).There was no statistical difference in serum vitamin D between branch and central retinal vein occlusion (P. value 0.34 ).
Conclusion: Vitamin D deficiency was more common in patients with retinal vein occlusion in realtion to healthy population.
Gambaran Status Gizi Dan Denyut Nadi Peserta Pelatihan Dasar Calon Pegawai Negeri Sipil Provinsi Jawa Tengah
Authors: Supriyono Supriyono , Magdalena Maria 
Published: January 2024

Salah satu cara untuk mengetahui tingkat kebugaran adalah dengan mengukur denyut nadi. Frekuensi denyut nadi untuk orang normal jumlahnya sama dengan denyut jantung. Tujuan dalam penelitian ini, mengetahui gambaran denyut nadi, dan status gizi pada peserta Pelatihan Dasar Calon Pegawai Negeri Sipil (Latsar CPNS) . Pengambilan sampel dalam penelitian ini adalah sampel jenuh dengan jumlah sampel sebanyak 34 orang peserta. Denyut nadi diukur dengan melakukan perabaan pada ujung lengan, yang dilakukan sebelum dan sesudah melakukan aktivitas. Kemudian untuk status gizi dengan cara mengukur tinggi badan dalam satuan centimeter dan berat badan dengan satuan kilogram. Kemudian dihitung dengan rumus indeks masa tubuh (IMT). Hasil penelitian ini menunjukkan peserta laki-laki mempunyai status gizi lebih baik dibandingkan wanita. Sedangkan rata-rata denyut nadi awal adalah 90,50 dan nadi akhir 121,76. Kenaikan denyut nadi terendah 9 dan tertinggi 49. Simpulan. Status gizi laki-laki lebih baik dibandingkan wanita. Perubahan denyut nadi laki-laki lebih baik dibandingkan Wanita.
PENGEMBANGAN EKOPRENEURSHIP DI SEKOLAH DASAR
Authors: Salam Indra Agus , Akbar M. Faisal , Andriani Tuti , Zein Rasyad 
Published: January 2024

Ecopreneurship merupakan ide yang belum digali oleh peneliti secara eksplisit dan menjadi inovasi pembelajaran di tahun 21st Namun, secara implisit konsep ini diyakini telah diterapkan di beberapa sekolah dasar namun belum ada penelitian lebih lanjut, oleh karena itu penelitian ini bertujuan untuk membuktikan dan memberikan gambaran perkembangan ecopreneurship di sekolah dasar. Penelitian ini menggunakan pendekatan kualitatif melalui metode deskriptif dengan subjek penelitian sebanyak 22 guru di sekolah dasar. Berdasarkan penelitian yang telah dilakukan dapat diketahui bahwa pengembangan ecopreneurship di sekolah dasar diintegrasikan dalam muatan kurikulum di sekolah yang berimplikasi pada terciptanya pembelajaran intrakurikuler, pembelajaran ekstrakurikuler dan ruang pamer berdasarkan konsep ecopreneurship. Secara kuantitatif terlihat bahwa 81,2% guru telah mencoba menerapkan prinsip-prinsip ekologi dalam pembelajaran di kelas dan 54.5% guru telah mencoba mengaitkannya dengan prinsip kewirausahaan. Hasil penelitian ini menjadi dasar peneliti dalam melakukan penelitian selanjutnya, selain itu hasil penelitian ini diharapkan dapat menjadi acuan bagi guru sekolah dasar dalam mengembangkan pembelajaran saat ini di 21st abad ini dan menjadi upaya preventif khususnya bagi Indonesia dalam mempersiapkan diri menuju Indonesia Emas 2045.
MDM2 gene a mplification in s kin c ancer p atients
Authors: Raghad Abbas Jabbar,  , Kareem Hamed Ghali  , Mohammed Naji Karim  
Published: January 2024

Skin cancer: Skin cancer is the uncontrolled proliferation of abnormal skin cells; skin cancer is classified into non-melanoma (squamous cell carcinoma and basal cell carcinoma) and melanoma. Approximately, 90% of skin cancers are caused by ultraviolet radiation, because of ultraviolet radiation emits to damage of skin cells DNA resulting in genetic mutations and formation of skin cancer.
Materials and methods: This study evaluated paraffin blocks from 17 specimen randomly selected from patients with skin cancer, and 6 specimens from patients non cancer patients as control group for comparison .This study was carried out in Laboratories of College of Science, Wasit University and AL Zahraa and ALKarama Teaching Hospitals, from October 2014 to April 2015. In this study MDM2( murine double minute 2) gene amplification was assessed by chromogenic in situ hybridization (CISH) technique.
Results: This study showed that there was no significant difference between skin cancer patients and control group in relation to MDM2 amplification (p>0.05), but presence of highly significant difference between patients of skin cancer and control group in relation to amplification intensity of MDM2 (p<0.05). Moreover, and according to histological type, our finding found significant difference between the types of skin cancer in relation to MDM2 amplification (p<0.05). Additionally, there were significant differences between patients of basal cell carcinoma and squamous cell carcinoma and control group in relation to MDM2 amplification(p<0.05).
Conclusion: We conclude that MDM2 amplification was high in types of skin cancer (BCC and SCC) because of MDM2 amplification in keratocytes of the epidermis may be associated with entry of these cells into the differentiation program.
On the Diversity of Phosphate Minerals for Potential Applications
Authors: Zhang Jin , Patel Shri , Gupta Surojit 
Published: January 2024

Abstract
This article describes the development of applications of phosphate-based materials and characterizes five non-apatite phosphate minerals using 3D optical profilometry. The results reveal the suitability of these materials for new uses in energy storage and conversion as well as medical applications.
IMPROVING LOCOMOTOR MOVEMENT ABILITY THROUGH THE FOLLOW JUMP GAME
Authors: Hidayatullah Muhammad Afsar , Hafiani Muhammad , Rasyid Ivan Nur , Tagap Bonnaeges Filemonn Sihananto , Anshari Hafiz , Nashih Muhammad , Kasanrawali Andi , Pratiwi Endang , Normawarni Halisa 
Published: January 2024

This study aims to determine the ability to move the movement through follow jump games for grade 2 education participants aged 7-8 years at SD Negeri Sungai Landas, Banjar Regency, South Kalimantan. The sample and subject studied are the following jumping games. This game was played by grade 2 students of Sungai Landas State Elementary School, Banjar Regency, South Kalimantan with a total of 17 students including 7 boys and 10 girls. This diversion was played by a review of 2 students of Sungai Landas State Elementary School, Banjar Rule, South Kalimantan with a total of 17 students including 7 boys and 10 girls. In this study, the first cycle data was obtained which were very low (0% < a score of ≤ 40%) with a total of 5 students, medium category (40% < a score of ≤ 55%) with a total of 0 students, medium category (55% < a score of ≤ 70%) with a total of 0 students, a high category (70% < a score of ≤ 85%) with a total of 12 students, and a very high category (85% < a score of ≤ 100%) with a total of 0 students. Cycle II states that the very low category (0% < a of score ≤ 40%) with 2 students, the low category (40% < a of score ≤ 55%) with 0 students, the medium category (55% < a score of ≤ 70%) with 0 students, the high category (70% < a score of ≤ 85%) with 0 students, and the very high category (85% < a score of ≤ 100%) with a total of 15 students. This article proposes the importance of learner movement in physical education learning in play take after follow jump games. Play take after follow jump game includes positive values, having important locomotor movements as a back in performing other, more complex progressions.
Impact of information on the number of traffic accidents on the outcome of the forecast
Authors: Gorzelanczyk Piotr 
Published: January 2024

Every year, more and more vehicles appear on the world's roads. This leads to increased traffic on the roads. Road accidents have become a rapidly growing threat. They cause loss of human life and economic assets. This is due to the rapid growth of the world's human population and the very rapid development of motorization. The main problem in forecasting and analyzing data on the number of traffic accidents is the small size of the dataset that can be used for analysis in this regard. And on the other hand, road accidents cause, globally, millions of deaths and injuries annually is their density in time and space. It is worth noting that the pandemic has reduced the number of traffic accidents. However, the value is still very high.
The purpose of the article is to assess the impact of information on the number of traffic accidents on the outcome of the forecast. To this end, using historical statistical data, the forecast of the number of traffic accidents for the following years was determined, and how this variability of the input data affects the value of the average percentage error of the forecast was determined. Based on the study, it can be concluded that a smaller number of input data, historical data on the number of accidents, instead of 32 years, 7 years, makes the determination of the forecast of the number of accidents for subsequent years, is at a satisfactory level, the average absolute percentage error of MAPE less than 7%. The article concludes with the determination of the forecast for future years. It is worth noting that the prevailing pandemic distorts the results obtained.
“Queria ter começado desde novo”: o esporte paralímpico na história de vida de um deficiente intelectual
Authors: Basei Andréia Paula , Carminato Ricardo Alexandre , Pereira Jhenifer da Silva 
Published: January 2024

Esta pesquisa objetivou analisar as influências do esporte paralímpico no desenvolvimento e na trajetória de vida da pessoa com deficiência intelectual (DI) a partir da história de vida de um atleta DI da modalidade de atletismo residente em um município de pequeno porte da mesorregião norte-central do Paraná. Evidenciou-se que, embora a história de vida do atleta DI é marcada por inúmeras dificuldades relacionadas, principalmente, com os aspectos financeiros e falta de incentivo para a prática esportiva até a fase da adolescência, o esporte teve/tem um papel extremamente importante como meio de inclusão social e melhoria da qualidade de vida, não somente nos aspectos relacionados à saúde, mas também, psicológicos, sociais e econômicos. Conclui-se que é de suma importância possibilitar o acesso à prática esportiva às pessoas com deficiência considerando os benefícios nos aspectos: físicos/motores, intelectual, social, afetivo e cultural no desenvolvimento como atleta e como cidadão. Ressalta-se como um dos meios a realização da extensão universitária, a qual tem o potencial de colocar em prática a responsabilidade social da universidade pública e contribuir para uma transformação efetiva da realidade.
PENGARUH KUALIAS AKTIVA PRODUKTIF TERHADAP PROFITABILITAS
Authors: Rosita Yeti , NR Ade Dian Nuridha , Junaedi Junaedi 
Published: January 2024

Perbankan menjadi salah satu faktor pendukung untuk memperbaiki perekonomian di suatu negara. semakin maju suatu negara maka, semakin besar peranan perbankan dalam mengendalikan negara tersebut, karena hampir semua sektor membutuhkan jasa bank. Profitabilitas bank sendiri menjadi hal yang penting bagi bank karena merepresentasikan kesehatan bank. Profitabilitas BPR intam Jabar mengalami penurunan selama lima tahun terakhir. Berdasarkan studi dokumentasi diperoleh informasi bahwa NPL pada BPR Intan Jabar mengalami kenaikan sedangkan ROA mengalami penurunan selama lima tahun terakhir. Kondisi paling buruk terjadi dalam dua tahun terakhir yaitu tahun 2021 dan 2022. Rata-rata ROA adalah sebesar -12. 354 sedangkan rata-rata NPL adalh sebesar 10,246%. Baik ROA maupun NPL pada BPR Intan Jabar kedua nya berada di bawah standar yang telah ditetapkan oleh Bank Indonesai, sehingga hal ini mengindikasikan berada pada keadaan tidak sehat. Hasil perhitungan menunjukan bahwa NPL memiliki pengaruh negatif terhadap ROA, dengan tingkat kontribusi pengaruh sebesar 27%. Artinya kontribusi NPL terhadap pembentukan ROA adalah sebesar 27% sedangkan 73% sisanya dipengaruhioleh faktor lain yang tidak diteliti dalam penelitian ini. Pengaruh negatif menunjukan bahwa ketika NPL naik maka ROA akan mengalami penurunan
Labor Market and Class Struggle from the Perspective of Marxist Political Economy
Authors: Sun Wanbing 
Published: January 2024

Within the viewpoint of Marxist political economy, inequalities in the labor market are regarded as products of class struggle under the capitalist system. These inequalities reflect the relatively disadvantaged position of the working class, who often face low wages, unstable working conditions, and exploitation. These injustices not only reflect economic structures but also deeply influence the construction of social status and power relations. Studying the organizational forms of the working class within this theoretical framework holds significant importance. Labor unions, as organizations representing workers' interests, undertake the responsibility of advocating for better working conditions and wages. Union organizations engage in collective actions, such as strikes and demonstrations, demonstrating the solidarity and strength of the working class, challenging the authority of the capitalist system.
A utilização de avaliação de participação e fatores contextuais para análise ampliada do neurodesenvolvimento infantil
Authors: Barros Camila Santos , Vieira Maria Fernanda , Ribeiro Carla Martins Trevisan 
Published: January 2024

Objetivo: Investigar o uso de instrumentos de avaliação de participação e fatores contextuais para permitir uma análise ampliada do neurodesenvolvimento de crianças de risco. Métodos: Estudo transversal, composto por crianças pré-termo, entre 3 e 42 meses. Foram excluídas aquelas com malformação congênita, síndrome genética e exposição à infecção congênita. Para a avaliação foram utilizados os instrumentos Escala Motora Infantil de Alberta (AIMS), Teste de Denver II, Child Engagement in Daily Life (CEDL), Affordances in the Home Environment for Motor Development (AHEMD) e um questionário estruturado elaborado pelas pesquisadoras. Resultados: Amostra de 29 crianças com maior prevalência de alteração nos domínios motor fino (34,5%) e amplo (24,1%); em relação à participação, 58,6% quase nunca brincavam ao ar livre com outras crianças e 75,9% quase nunca realizavam passeios de entretenimento; quanto aos fatores contextuais, observou-se baixa provisão de materiais de motricidade fina (46,4%) e grossa (57,1%) nas residências. Conclusão: Crianças com neurodesenvolvimento classificado como questionável tiveram alterações nos domínios de participação e fatores contextuais, apontando para a importância de uma avaliação mais detalhada. O uso de instrumentos para análise destes domínios auxiliou na compreensão ampliada do neurodesenvolvimento.
Portrait of Indonesian and Pakistan EFL Students’ Engagement in Online Classroom Based on Neuroscience Approach
Authors: Rukminingsih Rukminingsih , Novianti Hartia , Anees Muhammad , Rukmi Nala Sita 
Published: January 2024

The integration of neuroscience principles in online teaching can enhance student engagement and create a more engaging and brain-friendly learning experience. This study aims to portray the comparation of Indonesian and Pakistan EFL students’ behaviour, cognitive and emotional engagement in online classroom based on neuroscience approach. The participants in this research were students from Indonesian and Pakistan EFL students. The purposive sampling was used to select the participants who were taking from students of STKIP PGRI Jombang of English language education students from Indonesia and students of Government College Peshawar, Pakistan. This study employed a mixed case study by using a quantitative and qualitative data. The instruments of this study were close- ended and open-ended questionnaires. close-ended questionnaire. The quantitative data was analyzed by using descriptive statistics and the qualitative data was analyzed by thematic analysis. The findings showed that online learning in Indonesia and Pakistan shown to have positive levels of behavioral, cognitive and emotional engagement. The most positive engagement from both Indonesia and Pakistan students was behavioral engagement. Then, students’ cognitive engagement was more positive than emotional engagement. Then the finding also showed that the students engagement in Pakistan students was high positive level than Indonesia students.
A Study of the Metafunctions of Lombok Regional Slogans: Systemic Functional Linguistics Analysis
Authors: Syamsurrijal Syamsurrijal , Arniati Fitri 
Published: January 2024

Slogans are now an essential aspect of daily life, commonly encountered in both public businesses and industries such as soft drinks, food, fashion, cosmetics, and markets. While many slogans are written in the national language, numerous others are composed in local dialects. In Indonesia, every region has its own slogan in the local language. On the island of Lombok, there are four regions, and each has its own slogan in the local language, conveying a variety of messages to the inhabitants. But numerous people from Lombok, especially the younger generation, are unable to understand the meaning and message conveyed through the slogans. As a result, this study is aimed at (1). An analysis of the metafunction conveyed by district slogans on Lombok Island, WNT Province, and (2) Determine the type of transitivity system process that is predominantly used in district slogans on Lombok Island, WNT Province. The study employed a descriptive qualitative and quantitative research design. The sample respondents were selected through purposive sampling and data was collected using survey, observation, and interview methods. Results indicate that the slogan encompasses ideational, interpersonal, and textual metafunctions, and also involves material, mental, relational, behavioural, and extension transitivity system processes. Quantitatively, the slogan employs 28 types of processes, with material processes making up the majority (27%), followed by relational processes (23%) and behavioural processes (19%). The slogan text does not contain any verbal processes. Participants related to the slogan text include human resources, goals, actors, sensing, phenomena, and behaviour.