bluuebunny/crossref_metadata_2025_split huggingface dataset:
Unexpected behavioural adaptation of yellow fever mosquitoes in response to high temperatures
Authors: Hug David O. H. , Kropf Alida , Amann Marine O. , Koella Jacob C. , Verhulst Niels O. 
Published: February 2024

AbstractTemperature is a major ecological driver of mosquito-borne diseases as it influences the life-history of both the mosquito and the pathogen harboured within it. Understanding the mosquitoes’ thermal biology is essential to inform risk prediction models of such diseases. Mosquitoes can respond to temperatures by microhabitat selection through thermal preference. However, it has not yet been considered that mosquitoes are likely to adapt to changing temperatures, for example during climate change, and alter their preference over evolutionary time. We investigated this by rearing six cohorts of the yellow fever mosquito Aedes aegypti at two temperatures (24 °C, 30 °C) for 20 generations and used these cohorts to explicitly separate the effects of long-term evolution and within-generation acclimation on their thermal preferences in a thermal gradient of 20–35 °C. We found that warm-evolved mosquitoes spent 31.5% less time at high temperatures, which affects their efficiency as a vector. This study reveals the complex interplay of experimental evolution, rearing temperatures, and thermal preference in Ae. aegypti mosquitoes. It highlights the significance of incorporating mosquito microhabitat selection in disease transmission models, especially in the context of climate change.
Economic tolerance design of the P2 raceway based on the quasi-static model of aerospace ball bearings
Authors: Chang Zhou , Hu Lai , Cao Wenhan 
Published: February 2024

AbstractThis study focused on designing the raceway tolerance of high-precision rolling bearings. After the tolerance error equivalence relationship is defined, the application of the rolling bearing error equalization effect in tolerance design is studied. First, a five-degree of freedom quasi-static model was established for angular contact ball bearings. The waviness was included in the manufacturing error, and the radial and axial runouts of the bearing inner ring were calculated. Second, the error homogenization effect of the rolling bearing was studied, and the error homogenization coefficient was defined. The results of the study demonstrated that the bearing rotary accuracy was higher than the raceway error by an order of magnitude. Third, the manufacturing error range of each precision grade of the rolling bearing raceway was obtained by investigating errors of the equalization coefficient. Finally, the specific value of the raceway tolerance of P2 rolling bearings was obtained.
Incidental finding of leukaemia in circulating tumour DNA— the importance of a molecular tumour board
Authors: Mencel Justin , Rayarel Neha , Proszek Paula , Carter Paul , Feber Andy , Popat Sanjay , McVeigh Terri P. , George Angela , Dunlop Alan , Hardy Katy , Chau Ian , Cunningham David , Kohoutova Darina , Lee Richard , Iyengar Sunil , Starling Naureen 
Published: February 2024

AbstractAs the use of liquid biopsies are increasing across multiple indications in cancer medicine, the detection of incidental findings on circulating tumour DNA is of increasing importance. We report the finding of leukaemia detected in a patient who underwent plasma-based circulating tumour DNA next generation screening as part of a screening liquid biopsy study. A BRAF V600E mutation detected was deemed pathogenic following discussion at a molecular tumour board, and recommendation of further investigations led to the diagnosis of an occult haematological malignancy. We report the importance of molecular tumour board discussion and recommendations in the identification of incidental, pathogenic findings on circulating tumour DNA.
Assessment and management of frequency stability in low inertia renewable energy rich power grids
Authors: Saleem Muhammad Ismail , Saha Sajeeb , Roy Tushar Kanti , Ghosh Subarto Kumar 
Published: February 2024

AbstractThe integration of the renewable energy sources (RESs) into the power grid, drives a significant transformation in the conventional power generation landscape. This transition from traditional synchronous generators to inverter based RESs introduces unique challenges in maintaining the grid frequency stability due to the reduced system inertia. The inherent stochastic nature of the RES power generation, load demand, and grid inertia includes further complexity in the assessment of frequency stability. Existing studies have limitations, including neglecting the stochastic nature of RES generation and load demand fluctuations, relying on limited metrics, and lacking a comprehensive day‐to‐day assessment. To address these shortcomings of the existing approaches, this paper introduces a novel methodology for assessing frequency stability in power grids with high RES penetration. It proposes three indices for evaluating grid frequency sensitivity, resiliency, and permissibility amidst varying RES integration. Utilizing a stochastic approach, the study incorporates uncertainties in RES generation and load demand, offering a comprehensive framework for day‐to‐day frequency stability analysis. Additionally, it presents a systematic method to ascertain the necessary inertial support for maintaining desired frequency reliability in RES‐dominated grids. The effectiveness of these methodologies is validated through a case study on a modified IEEE 39‐bus test system, demonstrating their applicability in ensuring reliable grid operation under high RES scenarios.
Diverse branch feature refinement network for efficient multi‐scale super‐resolution
Authors: Zhang Dacheng , Zhang Wei , Lei Weimin , Chen Xinyi 
Published: February 2024

AbstractDespite the existence of various super‐resolution (SR) methods, most of them focus on designing models for specific upscaling factors rather than fully exploiting inter‐scale correlation to improve efficiency. In contrast, multi‐scale SR methods can effectively reduce the redundancy of network parameters by aggregating the feature extraction processes corresponding to multiple scales into a unified process. The aim of this study is to enhance the compactness and efficiency of the SR model. Thus, an efficient multi‐scale SR method called the diverse branch feature refinement network (DBFRN) is proposed. By decoupling the training process and inference process based on the idea of structural re‐parameterization, multi‐branch topology is adopted to enrich multi‐scale learning and merge branches to achieve efficient inference with equivalent effects. Specifically, two re‐parameterization strategies are designed and two corresponding feature refinement blocks for different feature levels in multi‐scale SR network. Extensive experiments demonstrate that the proposed multi‐scale SR method is effective and efficient, and it can outperform advanced single‐scale methods in terms of quantity and quality.
SSA‐UNet: Whole brain segmentation by U‐Net with squeeze‐and‐excitation block and self‐attention block from the 2.5D slice image
Authors: Jiang Shaofeng , Chen Xingyan , Yi Chen 
Published: February 2024

AbstractWhole brain segmentation from magnetic resonance images (MRI) is crucial in diagnosing brain diseases and analyzing neuroimaging data. Despite advances through deep learning, challenges such as uneven gray distribution and the presence of artifacts still present hurdles in medical image processing. These limitations are often a result of insufficient spatial contextual information and lack of attention to important regions within existing models. To address these issues, this paper presents SSA‐UNet (Squeeze‐and‐Excitation and Self‐Attention UNet), a uniquely designed deep convolutional neural network that integrates spatial constraints by converting three consecutive 2D MRI slices into a single 2.5D image. This facilitates capturing inter‐slice dependencies effectively. Additionally, the newly formulated SSA block, which sequentially incorporates channel attention and Self‐Attention mechanisms, is placed before the decoders in the conventional U‐Net architecture. This enables the network to automatically weight different feature maps and focus more effectively on regions requiring precise segmentation. Rigorous evaluations on LPBA40 and IBSR18 datasets substantiate the remarkable improvements in accuracy and stability achieved by SSA‐UNet. Results indicate Dice coefficients of 98.38% and 97.47%, specificity of 99.69% and 99.57%, and sensitivity of 98.5% and 97.98% for the respective datasets. Compared to other existing models, SSA‐UNet shows significant improvements on both the LPBA40 and IBSR18 datasets. On the LPBA40 dataset, SSA‐UNet's Dice coefficient improved by 0.33% compared to the sub‐optimal model, while on the IBSR18 dataset, the improvement reached 1.78%. These empirical findings demonstrate SSA‐UNet's heightened capability in addressing the long‐standing challenges in MRI‐based whole‐brain segmentation.
Estudio de parámetros de perfil nutricional, color y aromas en el vino sin alcohol “WIN”, a través de diferentes técnicas de desalcoholización de vinos (columna de conos rotatorios y ósmosis inversa)
Authors: Carlos Moro Luis , Pinto Julio A. , Villanueva Sonia , Sevillano María 
Published: February 2024

Resumen
Bodega Win junto con LAAE y el CREG de la Universidad de Zaragoza han desarrollado un proyecto de investigación, “Alcoholess”, que ha permitido adquirir conocimientos de índole científico y tecnológico para desalcoholizar parcial o totalmente vinos sin apenas modificar su composición aromática y sensorial. Los resultados del proyecto enfocados a la desalcoholización parcial avalan que la técnica de Ósmosis Inversa es la más idónea para paliar los efectos del cambio climático en vinos, al permitir reducir su graduación alcohólica hasta 1⁰ Alc sin que sus componentes aromáticos sufran alteraciones. Las investigaciones realizadas sobre la desalcoholización total de vinos revelan que es posible conservar la tipicidad de la variedad de uva en el vino sin alcohol mediante la optimización de los parámetros del proceso de desalcoholización por Columna de Conos Rotatorios (CCR) y la aplicación de estrategias enológicas optimizadas para su posterior reconstitución. Los vinos desalcoholizados obtenidos y comercializados bajo la marca Win mantienen todas las características organolépticas de los vinos de origen y se sitúan en una posición privilegiada con respecto a su competencia actual, gracias a su bajo contenido en azúcares.
Un nuevo método basado en inteligencia artificial para evaluar la ingesta individual de vino
Authors: Cobo Miriam , de la Guía Edgard Relaño , Heredia Ignacio , Aguilar Fernando , Lloret-Iglesias Lara , García Daniel , Yuste Silvia , Recio-Fernández Emma , Pérez-Matute Patricia , José Motilva M. , Moreno-Arribas M. Victoria , Bartolomé Begoña 
Published: February 2024

Resumen
Este estudio surge de la necesidad de nuevas metodologías que permitan cuantificar el consumo de vino con mayor precisión, para posteriormente utilizar esta información en estudios observacionales de alimentación-salud y estudios de intervención de dieta. Se ha desarrollado un algoritmo basado en un método de “aprendizaje profundo”, que permite determinar el volumen de vino en una copa/vaso a partir de una fotografía, y se ha validado en un estudio de consumidores realizado a través de una aplicación web. La aplicación del modelo a imágenes “cuasi-reales” y a imágenes "reales" (obtenidas a partir del estudio de consumidores), ha mostrado una precisión satisfactoria con un error absoluto medio (MAE) de 10 mL y 26 mL, respectivamente. En relación a las pautas de consumo de vino observadas en el estudio de consumidores (n=38), el volumen medio de vino tinto servido en una copa fue de 114±33 mL, sin estar condicionado por factores como el sexo del consumidor, el momento de consumo, el tipo de vino, o el formato de copa/vaso. En síntesis, el sistema de aprendizaje profundo desarrollado junto con la aplicación web, constituyen una herramienta de gran valor para la estimación precisa del volumen de vino consumido diariamente, así como las pautas de su consumo, de gran utilidad para estudios poblacionales.
Regioselective C3-Formylation of 2H-Indazoles Using Selectfluor under Microwave-Assisted Conditions
Authors: Pitchai Manivel , Vetrichelvan Muthalagu , Kaspady Mahammed , Indasi Gopikumar , Krishnan Rajesh , Maheswarappa Gururaju Sannakki , Mathur Arvind , Gupta Anuradha 
Published: February 2024

AbstractAn efficient microwave-assisted Selectfluor-mediated regioselective C3-formylation of 2H-indazoles bearing a variety of alkyl and aryl substituents using DMSO as the formylating agent has been developed. This methodology provides access to 3-formyl 2H-indazoles with moderate to excellent yields. These functionalized indazoles are potentially useful as templates for drug discovery. Control experimental results suggest that this formylation probably proceeds through a radical pathway.
Evaluation of the Effect of Ununion Percentage of Scaphoid on Stress and Displacement of Fragment Part of Scaphoid in Various Degrees of Wrist Extension with and without External Force
Authors: Niknam Saeed , Namazi Hamid , Karimi Mohammad Taghi 
Published: February 2024

Abstract
Background Scaphoid fractures are almost two-thirds of different kinds of carpal fractures. Surgeons usually have challenges in deciding if the wrist should be mobilized or immobilized for the patients with different percentiles of partial union of scaphoid. This study's aim was to investigate different percentiles of union (25–50–75) in waist and proximal pole of scaphoid fracture to find the union percentile which can tolerate normal daily activities to help surgeons in taking appropriate decisions in this regard.
Method A model of wrist joint was developed in this study based on computed tomography scan images of wrist joint. Various percentage of union in waist and proximal poles of scaphoid with and without internal fixation were tested in this study. The stress applied on scaphoid and displacement of fragment parts were evaluated in Abaqus software during motion of wrist from neutral to 40 degrees of extension.
Results Although Von Mises stress of scaphoid bone increased following use of external force, the difference was significant for conditions 3 and 6 (75% of union in middle and distal parts). The stress applied on scaphoid increased depends on conditions (ununion percentage of bone). Moreover, its stress depends on the angle of wrist extension. Use of internal fixation screw decreased stress of scaphoid in most of conditions.
Conclusion The stress developed in scaphoid depends on the nonunion percentage of scaphoid and the amount of motion of wrist joint. It is better to use external fixation screw especially for conditions 3 and 6 (75% of union in middle and distal parts) to decrease the displacement of fragment parts and to decrease the stress applied on scaphoid in wrist extension.
Type of Study and Level of Evidence Case study, level of evidence: III.
Prognostic Value of Symptoms and Signs in Geriatric Acute Pulmonary Embolism—An Analytical Study
Authors: Özdemir Serdar , Özkan Abuzer 
Published: February 2024

Abstract
Objective The aim of this study was to evaluate the relationship between symptoms and short-term mortality in geriatric patients presenting to the emergency department with acute pulmonary embolism.
Materials and Methods This retrospective cohort study was conducted to evaluate the data of geriatric patients admitted to the emergency department between September 01, 2022, and March 01, 2023. The study population comprised patients who presented with acute pulmonary embolism signs and symptoms. Demographic data, vital parameters, and symptoms were noted.
Results Of the 176 patients included in the final analysis, 55 (31.2%) were female. The median of age was 76 (25th–75th percentile: 72–82.5) years. The most common symptoms were dyspnea (61.9%), fatigue (27.2%), and syncope (23.8%). There was no statistically significant difference between the survivor and nonsurvivor groups in terms of symptoms (p-values for dyspnea, syncope, chest pain, back pain, hemoptysis, extremity pain, and fatigue: 0.804, 0.765, 0.154, 0.543, 0.675, 0.342, and 0.943, respectively) (chi-squared test).
Conclusion In patients presenting to the emergency department with acute pulmonary embolism, clinicians should not prioritize based on symptoms but should evaluate patients according to clinical severity scores.
Reconstruction of Filarial Penis and Scrotum
Authors: Sharma Dr. L. K. 
Published: February 2024

SummaryEight cases of mild to severe degrees of elephantiasis scrotum and pents have been treated. The procedure followed in the present series was total - excision of the penile skin and free skin graft. Reduction of the scrotum by excising all the discased subcutaneous tissue and reconstruction of the scrotum by by scrotal flaps. The cosmatic and functional results have been presented. This procedure to reduce the size of scrotum and penis is most practical to relieve the patient from the great social embarrassment.
Embolization of an Intracranial Vertebral Artery Aneurysm via the Deep Cervical Artery
Authors: Schulz Katharina , Grieb Dominik , Boxberg Frederik , Blaeser Klaus , Scholz Martin , Schlunz-Hendann Martin 
Published: February 2024

AbstractTreatment of vertebral artery aneurysms can be challenging due to the unusual vascular anatomy or unfeasibility of traditional endovascular techniques. We describe a novel approach for endovascular treatment of a ruptured intracranial vertebral artery aneurysm with bilateral vertebral artery occlusions and hypoplasia of the posterior communicating arteries. Successful coil embolization was performed using a collateral pathway for microcatheterization via anastomosis between the deep cervical artery and the vertebral artery. This case report highlights a novel alternative endovascular treatment approach for vertebrobasilar aneurysms in case of a poor vascular status with occlusion or lack of traditional endovascular access routes.
Safety of female ride-hailing passengers: Perception and prevention
Authors: Hu Shixingyue , Yang Yazao 
Published: February 2024

AbstractRide-hailing, as part of wider transitions to smart city, has emerged as a beneficial complement to urban public transport. However, the frequent occurrence of ride-hailing safety accidents in multiple countries has raised concerns about passenger safety on an international scale. Within this context, this study aims to investigate female passengers’ safety perception and prevention action when using ride-hailing services, helping establish better management and protection mechanisms for passenger safety. Using objective data from 7898 ride-hailing criminal adjudications (674 passenger victimizations) and subjective data from 596 Chinese female respondents, the safety perception scale and prevention tendency scale, with six potential variables, are developed to further examine the heterogeneity of perception and prevention. Results reveal that driver’s words and actions directly influence female passengers’ safety judgments regarding ride-hailing services and that traveling with companions significantly enhances their perceived safety. The main preventative actions identified include relying on mobile phones for information and communication, as well as avoiding risky ride-hailing situations. Furthermore, the analysis of individual heterogeneity has uncovered perception and prevention differences based on factors such as age, education level, residence conditions, ride-hailing frequency, and victimization experiences. These differences are evident in perception biases towards driver attitudes and accompanying travel, as well as variations in risk avoidance behaviors. The insights inductively derived hold fundamental conceptual and empirical value for scholarship on safety evaluation and crime prevention in the context of shared mobility. Additionally, the countermeasures proposed in this study can serve as a theoretical reference for enhancing the safety supervision of ride-hailing services, contributing to the establishment of safer, more reliable and more sustainable shared travel environment.
Occurrence, spatial distribution, risk assessment, and management of environmental estrogens in surface waters of the Taihu basin
Authors: Wang Minhao , Ding Hongran , Liang Guiyu , Wang Xueyin , Yang Luyue , Tong Ting , Li Dongling , Zhou Xiao , Zhang Haifei , Wang Fang , Tie Xiaowei , Han Lei 
Published: February 2024

Environmental context Environmental estrogens can disrupt the normal functioning of endocrine systems, and their occurrence in drinking water sources could cause potential health risk. We investigated concentrations of four estrogens in the lakes from the Taihu Basin, and found that BPA and EE2 were elevated in some sites. However, concentrations of all four environmental estrogens were below the national standards, and caused no health threat to local population. Rationale The Taihu Basin is a critical freshwater ecosystem susceptible to contamination from various anthropogenic activities. Environmental estrogens (also known as endocrine disrupting chemicals, EDCs) are exogenous substances that can disrupt the normal functioning of endocrine systems. The contamination of water by EDCs is primarily caused by effluents from sewage treatment plants and livestock poultry farms. In this study, we assessed the spatial distribution and potential risks of environmental estrogens in surface water in the Taihu basin. Various statistical evaluations were employed to establish connections between measured concentration of heavy elements, estrogens and physicochemical parameters, to identify potential sources of these contaminants. Methodology Water samples from 44 sampling points in five lakes in Suzhou were taken for evaluation of environmental estrogens. Gas chromatography–mass spectrometry was used for identification of concentrations of estrone (E1), estradiol (E2), ethinyl estradiol (EE2) and bisphenol A (BPA). Inductively coupled plasma–mass spectrometry was employed to identify heavy element concentrations in water samples. Results Environmental estrogen concentrations were detected ranging from 0.001 to 209 ng L–1, with the highest attributed to BPA, whereas E1, E2 and EE2 were comparatively lower. Correlation evaluation between environmental estrogens, physicochemical parameters and heavy element contents revealed a positive correlation (P < 0.05) between the total chromium and environmental estrogen contents. Consequently, the risk entropy value of Shanghu Lake exceeded 0.5, indicating a potentially high risk of estrogenic activity. Discussion The widespread distribution and high concentrations of BPA in freshwater raise urgent concerns, highlighting the need for frequent monitoring of environmental estrogens in surface waters throughout the year to mitigate potential risks in the future. Our results suggest that a potential estrogen risk exists in the Shanghu Lake in the Taihu basin. Potential treatment methods for endocrine disruptors have been proposed, which could provide actionable plans for stakeholders.