bluuebunny/crossref_metadata_2025_split huggingface dataset:
Localized Cutaneous Hyalohyphomycosis Caused by a
Fusarium
Species Infection in a Renal Transplant Patient
Authors: Cocuroccia Barbara , Gaido Jeanette , Gubinelli Emanuela , Annessi Giorgio , Girolomoni Giampiero 
Published: February 2003

ABSTRACT

Fusariosis is a hyalohyphomycosis due to
Fusarium
species that mainly occurs in immunocompromised hosts. The clinical spectrum of
Fusarium
infection comprises localized and disseminated forms. A case of localized cutaneous fusariosis caused by
Fusarium solani
in a renal transplant patient is described, and the skin manifestations of the disease are discussed.
Tissue Adhesives for Traumatic Lacerations: A Systematic Review of Randomized Controlled Trials*
Authors: Farion Ken J. , Osmond Martin H. , Hartling Lisa , Russell Kelly F. , Klassen Terry P. , Crumley Ellen , Wiebe Natasha 
Published: February 2003

Abstract Objective: To summarize the best available evidence for the effect of tissue adhesives (TAs) in managing traumatic lacerations in children and adults. Methods: A search was conducted using the Cochrane Controlled Trials Register, Medline, and EMBase for relevant studies. The authors also searched the citations of selected studies and contacted relevant authors and manufacturers. The search included randomized controlled trials (RCTs) comparing a TA versus standard wound closure (sutures, staples, adhesive strips) (SWC) or two TAs for acute, linear, low‐tension, traumatic lacerations in an emergency or primary care setting. Data were extracted by one reviewer and checked for accuracy by a second reviewer. Two reviewers independently assessed masked copies for quality. Outcomes of cosmesis (subgroups of age, wound location, and need for deep sutures), pain, procedure time, ease of use, and complications were analyzed separately for two comparisons: 1) TA versus SWC; and 2) TA versus TA. Results: Eight studies compared a TA with SWC. No significant difference was found for cosmesis at any time point examined. Subgroup analysis was possible only for age; no significant difference was found. Pain scores [Parent Visual Analogue Scale weighted mean difference (VAS WMD) =−15.7 mm; 95% CI =−21.9 to −9.5] and procedure time (WMD =−5.7 minutes; 95% CI =−8.2 to −3.1) significantly favored TAs. Small, statistically significant risk differences were found for dehiscence [favoring SWC; number needed to harm (NNH) = 25; 95% CI = 14 to 100] and erythema (favoring TAs; NNH = 8; 95% CI = 4 to 100). Only one study compared two TAs (butylcyanoacrylate versus octylcyanoacrylate) for pediatric facial lacerations. No significant difference was found for cosmesis, pain, procedure time, or complications. Conclusions: TAs are an acceptable alternative to SWC for simple traumatic lacerations. No difference in cosmesis was found between TAs and SWC, or between different TAs. Tissue adhesives offer the benefits of decreased procedure time and less pain, compared with SWC. A small increased rate of dehiscence with TAs must be considered when choosing the closure method (NNH = 25).
A Survey of the Emergency Department Population and Their Interest in Preventive Health Education
Authors: Llovera Ingrid , Ward Mary F. , Ryan James G. , LaTouche Thalia , Sama Andrew 
Published: February 2003

Abstract Objective: To determine which preventive health information the emergency department (ED) population (patients and visitors) would be most interested in having available to them while they spend time in the waiting area. Methods: This was a prospective survey of consecutive adults seated in the ED waiting area during a representative week on predetermined shifts. The survey asked them to indicate whether they would be interested in obtaining information about the following preventive health issues: breast cancer, prostate cancer, smoking, obesity, stress reduction, exercise programs, alcohol/drugs, HIV, blood pressure screening, immunizations, referrals to primary care physicians, Pap smears, car safety, smoke detectors, domestic and youth violence, depression, gun safety, and safe sex. Results: Of the 1,284 subjects approached, 878 (68%) made up the study group (56% female, mean age = 44 years, 60% white); 406 refused. The information people were most interested in obtaining was the following: 52% of the respondents were interested in referral to stress reduction programs, 51% in information about exercise programs, 42% in blood pressure screening, 40% in information about breast cancer screening, 33% in depression information/screening, 33% in prostate cancer screening, 26% in immunization against pneumococcus, 24% in immunization against tetanus, 26% in smoking cessation programs, and 26% in safe driving information. Women were most interested in breast cancer screening (64%); and men, in prostate cancer screening (55%). Conclusions: Of the 878 subjects in the study group, 96% were interested in obtaining information about one or more preventive health issues. An opportunity exists to respond to this interest by providing material for public health education in the waiting area of EDs.
Analysis of Clinical Samples of Pancreatic Cyst's Lesions with A Multi‐Analyte Bioelectronic Simot Array Benchmarked Against Ultrasensitive Chemiluminescent Immunoassay
Authors: Scandurra Cecilia , Björkström Kim , Caputo Mariapia , Sarcina Lucia , Genco Enrico , Modena Francesco , Viola Fabrizio Antonio , Brunetti Celestino , Kovács‐Vajna Zsolt M. , Franco Cinzia Di , Haeberle Lena , Larizza Piero , Mancini Maria Teresa , Österbacka Ronald , Reeves William , Scamarcio Gaetano , Wheeler May , Caironi Mario , Cantatore Eugenio , Torricelli Fabrizio , Esposito Irene , Macchia Eleonora , Torsi Luisa 
Published: January 2024

AbstractPancreatic cancer, ranking as the third factor in cancer‐related deaths, necessitates enhanced diagnostic measures through early detection. In response, SiMoT‐Single‐molecule with a large Transistor multiplexing array, achieving a Technology Readiness Level of 5, is proposed for a timely identification of pancreatic cancer precursor cysts and is benchmarked against the commercially available chemiluminescent immunoassay SIMOA (Single molecule array) SP‐X System. A cohort of 39 samples, comprising 33 cyst fluids and 6 blood plasma specimens, undergoes detailed examination with both technologies. The SiMoT array targets oncoproteins MUC1 and CD55, and oncogene KRAS, while the SIMOA SP‐X planar technology exclusively focuses on MUC1 and CD55. Employing Principal Component Analysis (PCA) for multivariate data processing, the SiMoT array demonstrates effective discrimination of malignant/pre‐invasive high‐grade or potentially malignant low‐grade pancreatic cysts from benign non‐mucinous cysts. Conversely, PCA analysis applied to SIMOA assay reveals less effective differentiation ability among the three cyst classes. Notably, SiMoT unique capability of concurrently analyzing protein and genetic markers with the threshold of one single molecule in 0.1 mL positions it as a comprehensive and reliable diagnostic tool. The electronic response generated by the SiMoT array facilitates direct digital data communication, suggesting potential applications in the development of field‐deployable liquid biopsy.
Ionic Strength‐Mediated “DNA Corona Defects” for Efficient Arrangement of Single‐Walled Carbon Nanotubes
Authors: Luo Yuanyuan , Wu Na , Niu Liqiong , Hao Pengyan , Sun Xiaoya , Chen Feng , Zhao Yongxi 
Published: January 2024

AbstractSingle‐stranded DNA oligonucleotides wrapping on the surface of single‐walled carbon nanotubes (SWCNTs), described as DNA corona, are often used as a dispersing agent for SWCNTs. The uneven distribution of DNA corona along SWCNTs is related to the photoelectric properties and the surface activity of SWCNTs. An ionic strength‐mediated “DNA corona defects” (DCDs) strategy is proposed to acquire an exposed surface of SWCNTs (accessible surface) as large as possible while maintaining good dispersibility via modulating the conformation of DNA corona. By adjusting the solution ionic strength, the DNA corona phase transitioned from an even‐distributed and loose conformation to a locally compact conformation. The resulting enlarged exposed surface of SWCNTs is called DCDs, which provide active sites for molecular adsorption. This strategy is applied for the arrangement of SWCNTs on DNA origami. SWCNTs with ≈11 nm DCD, providing enough space for the adsorption of “capture ssDNA” (≈7 nm width required for 24‐nt) extended from DNA origami structures are fabricated. The DCD strategy has potential applications in SWCNT‐based optoelectronic devices.
Metabolic and other morbid complications in congenital generalized lipodystrophy type 4
Authors: Akinci Gulcin , Alyaarubi Saif , Patni Nivedita , Alhashmi Nadia , Al‐Shidhani Azza , Prodam Flavia , Gagne Nancy , Babalola Funmbi , Al Senani Aisha , Muniraj Kavitha , Elsayed Solaf M. , Beghini Marianna , Saydam Basak Ozgen , Allawati Moosa , Vaishnav Madhumati S. , Can Ender , Simsir Ilgin Y. , Sorkina Ekaterina , Dursun Fatma , Kamrath Clemens , Cavdar Umit , Chakraborty Partha P. , Dogan Ozlem Akgun , Al Hosin Aliya , Al Maimani Ashwaq , Comunoglu Nil , Hamed Ahmed , Huseinbegovic Tea , Scherer Thomas , Curtis Jacqueline , Brown Rebecca J. , Topaloglu Haluk , Simha Vinaya , Wabitsch Martin , Tuysuz Beyhan , Oral Elif A. , Akinci Baris , Garg Abhimanyu 
Published: January 2024

AbstractMorbidity and mortality rates in patients with autosomal recessive, congenital generalized lipodystrophy type 4 (CGL4), an ultra‐rare disorder, remain unclear. We report on 30 females and 16 males from 10 countries with biallelic null variants in CAVIN1 gene (mean age, 12 years; range, 2 months to 41 years). Hypertriglyceridemia was seen in 79% (34/43), hepatic steatosis in 82% (27/33) but diabetes mellitus in only 21% (8/44). Myopathy with elevated serum creatine kinase levels (346–3325 IU/L) affected all of them (38/38). 39% had scoliosis (10/26) and 57% had atlantoaxial instability (8/14). Cardiac arrhythmias were detected in 57% (20/35) and 46% had ventricular tachycardia (16/35). Congenital pyloric stenosis was diagnosed in 39% (18/46), 9 had esophageal dysmotility and 19 had intestinal dysmotility. Four patients suffered from intestinal perforations. Seven patients died at mean age of 17 years (range: 2 months to 39 years). The cause of death in four patients was cardiac arrhythmia and sudden death, while others died of prematurity, gastrointestinal perforation, and infected foot ulcers leading to sepsis. Our study highlights high prevalence of myopathy, metabolic abnormalities, cardiac, and gastrointestinal problems in patients with CGL4. CGL4 patients are at high risk of early death mainly caused by cardiac arrhythmias.
Ultrastable, Superrobust, and Recyclable Supramolecular Polymer Networks
Authors: Niu Wenwen , Li Zequan , Liang Fengli , Zhang Houyu , Liu Xiaokong 
Published: January 2024

AbstractSupramolecular polymer networks (SPNs), crosslinked by noncovalent bonds, have emerged as reorganizable and recyclable polymeric materials with unique functionality. However, poor stability is an imperative challenge faced by SPNs, because SPNs are susceptible to heat, water, and/or solvents due to the dynamic and reversible nature of noncovalent bonds. Herein, the design of a noncovalent cooperative network (NCoN) to simultaneously stabilize and reinforce SPNs is reported, resulting in an ultrastable, superrobust, and recyclable SPN. The NCoN is constructed by multiplying the H‐bonding sites and tuning the conformation/geometry of the H‐bonding segment to optimize the multivalence cooperativity of H‐bonds. The rationally designed H‐bonding segment with high conformational compliance favors the formation of tightly packed H‐bond arrays comprising higher‐density and stronger H‐bonds. Consequently, the H‐bonded crosslinks in the NCoN display a covalent crosslinking effect but retain on‐demand dynamics and reversibility. The resultant ultrastable SPN not only displays remarkable resistance to heat up to 120 °C, water soaking, and a broad spectrum of solvents, but also possesses a superhigh true stress at break (1.1 GPa) and an ultrahigh toughness (406 MJ m−3). Despite the covalent‐network‐like stability, the SPN is recyclable through activating its reversibility in a high‐polarity solvent heated to a threshold temperature.
Shape‐Assisted Self‐Assembly of Hexa‐Substituted Carpyridines into 1D Supramolecular Polymers
Authors: Gallego Lucía , Woods Joseph F. , Butti Rachele , Szwedziak Piotr , Vargas Jentzsch Andreas , Rickhaus Michel 
Published: January 2024

AbstractThe extent of the influence that molecular curvature plays on the self‐assembly of supramolecular polymers remains an open question in the field. We began addressing this fundamental question with the introduction of “carpyridines”, which are saddle‐shaped monomers that can associate with one another through π–π interactions and in which the rotational and translational movements are restricted. The topography displayed by the monomers led, previously, to the assembly of highly ordered 2D materials even in the absence of strong directional interactions such as hydrogen bonding. Here, we introduce a simple strategy to gain control over the dimensionality of the formed structures yielding classical unidimensional polymers. These have been characterized using well‐established protocols allowing us to determine and confirm the self‐assembly mechanism of both fibers and sheets. The calculated interaction energies are significantly higher than expected for flexible self‐assembling units lacking classical “strong” non‐covalent interactions. The versatility of this supramolecular unit to assemble into either supramolecular fibers or 2D sheets with strong association energies highlights remarkably well the potential and importance of molecular shape for the design of supramolecular materials and the applications thereof.
Preparation of highly selective nanofiltration composite membranes based on a novel soluble rigidly contorted monomer
Authors: Zhou Jing , Liu Zhenyu , Jiang Chi , Hou Yingfei 
Published: January 2024

AbstractNanofiltration composite membranes with high selectivity are one of the most critical cores in water treatment, and regulating the surface charge and pore structure of active separation layers in thin film composite membranes is one of the most effective means to improve the selectivity of composite membranes. This article synthesized a novel monomer with positive charge and a rigid twisted Tröger's base structure (named TBDA‐SO3), which was manipulated to improve the microporous structure and surface charge of the composite membrane. By interfacial polymerization, TBDA‐SO3, and piperazine were co‐reacted with trimesoyl chloride to successfully prepare positively charged, highly selective, and strongly microporous polyamide composite nanofiltration membranes. The best‐performing composite nanofiltration membrane in this article has a permeability similar to that of the control group's poly(piperazine amide) (PPA) membrane (pure water flux, 7.8 L m−2 h−1 bar−1), but has excellent divalent cation selectivity (52.57), which is 4.4 times that of the control group's PPA membrane.
Photoluminescent and tough hydrogels from silk fibroin and polyacrylic acid complexed with europium
Authors: Zhao Yu , Puthia Manoj , Jo Seong‐Min , Guan Juan , Liu Mingjie , Wu Sujun 
Published: January 2024

AbstractBiocompatible, tough, and photoluminescent hydrogels are highly desirable for biomedical applications in vivo. Herein, hybrid hydrogels prepared from silk fibroin (SF) and polyacrylic acid (PAA) and complexed with europium, named as SF‐PAA‐Eu3+ hydrogels, exhibit good comprehensive properties. Owing to the intensive molecular interactions among SF, PAA, and Eu3+, SF‐PAA‐Eu3+ hydrogels show a greatest tensile strength of 0.58 MPa, elongation of 443%, and work of fracture of 1.65 MJ/m. In vivo imaging experiment in a mouse subcutaneous implantation model revealed excellent and sustained photoluminescence of the SF‐PAA‐Eu3+ hydrogels for 24 h. The work provides a strategy for designing functional SF‐based hydrogels for imaging applications in vivo.
Near‐infrared light response novel shape memory actuator based on photothermal rGO‐TiO2 filler
Authors: Zhang You , Ma Wenzhong , Zhong Jing , Jiang Ruiqiao , Zhou Zhou , Lu Sirui , Wang Shuo 
Published: January 2024

AbstractAs an efficient method to realize photoinduced shape memory, photothermal filler has the characteristics of economy and convenience. However, the aggregation of the photothermal filler in the matrix material will reduce the material's shape memory and mechanical properties. In this work, the photothermal filler of reduced graphene oxide (rGO)‐titanium dioxide (TiO2) was prepared by the solvothermal method and then introduced into the polycaprolactone (PCL) matrices to construct a photoresponsive actuator. Because of TiO2 is uniformly loaded on the rGO surface, rGO‐TiO2 disperses well in the composites. When the GO:TiO2 ratio of photothermal filler is 1:1, the mechanical properties of PCL‐GT‐3 are the best, and the tensile strength and elongation at break are 31.8 MPa and 239.5%, respectively, and the crosslinking material under near‐infrared light has a good photothermal effect. Due to the induced difference between the in‐plane stress of the surface and the volume layer, the shape transformation can be controlled by very low energy (808 nm, 700 mW near‐infrared laser). The scheme of controlling the properties of the photoinduced shape memory material by changing only the filler type is conducive to commercial application.
FloraTraiter: Automated parsing of traits from descriptive biodiversity literature
Authors: Folk Ryan A. , Guralnick Robert P. , LaFrance Raphael T. 
Published: January 2024

AbstractPremisePlant trait data are essential for quantifying biodiversity and function across Earth, but these data are challenging to acquire for large studies. Diverse strategies are needed, including the liberation of heritage data locked within specialist literature such as floras and taxonomic monographs. Here we report FloraTraiter, a novel approach using rule‐based natural language processing (NLP) to parse computable trait data from biodiversity literature.MethodsFloraTraiter was implemented through collaborative work between programmers and botanical experts and customized for both online floras and scanned literature. We report a strategy spanning optical character recognition, recognition of taxa, iterative building of traits, and establishing linkages among all of these, as well as curational tools and code for turning these results into standard morphological matrices.ResultsOver 95% of treatment content was successfully parsed for traits with <1% error. Data for more than 700 taxa are reported, including a demonstration of common downstream uses.ConclusionsWe identify strategies, applications, tips, and challenges that we hope will facilitate future similar efforts to produce large open‐source trait data sets for broad community reuse. Largely automated tools like FloraTraiter will be an important addition to the toolkit for assembling trait data at scale.
An updated and extended version of the Melastomataceae probe set for target capture
Authors: Dagallier Léo‐Paul M. J. , Michelangeli Fabián A. 
Published: January 2024

AbstractPremiseA probe set was previously designed to target 384 nuclear loci in the Melastomataceae family; however, when trying to use it, we encountered several practical and conceptual problems, such as the presence of sequences in reverse complement, intronic regions with stop codons, and other issues. This raised concerns regarding the use of this probe set for sequence recovery in Melastomataceae.MethodsIn order to correct these issues, we cleaned the Melastomataceae probe set, extended it with additional sequences, and compared its performance with the original version.ResultsThe final probe set targets 396 putative nuclear loci represented by 6009 template sequences. The probe set has been made available, along with details on the cleaning process, for reproducibility. We show that the new probe set performs better than the original version in terms of sequence recovery.DiscussionThis updated, extended, and cleaned probe set will improve the availability of phylogenomic resources across the Melastomataceae family. It is fully compatible with sequence recovery and extraction pipelines. The cleaning process can also be applied to any plant‐targeting probe set that would need to be cleaned or updated if new genomic resources for the targeted taxa become available.
Mapping school‐level language policies across multilingual secondary schools in England: An ecology of English, modern languages and community languages policies
Authors: Forbes Karen , Morea Nicola 
Published: January 2024

AbstractLanguage plays a crucial role in education; yet, while issues of language are undoubtedly relevant to all teachers, school‐level language policies, which aim to provide explicit guidance underpinned by a clear set of principles, are too often conspicuous by their absence. In a range of educational contexts around the world it has been found that where such policies do exist, they are frequently fragmented and underpinned by monolingual ideologies that do not reflect the linguistic diversity of schools today. The aim of this study, therefore, is to map the provision of school‐level policies from a representative sample of secondary schools in England (n = 998) and explore the extent to which they address (either implicitly or explicitly) the following dimensions of language: (a) English, both as the language of instruction and in relation to support for English as an additional language (EAL) learners; (b) modern languages in the curriculum; and (c) other home or community languages. Drawing on an ecologically informed approach, where these three dimensions of language are conceptualised as systems, analysis was conducted to identify areas of divergence and (potential for) intersection. Findings suggest that policies relating to languages, where they exist, are largely compartmentalised and tensions emerged between the various systems. However, we also note several promising points of intersection which indicate that there is scope for developing cohesive and holistic languages policies at a whole‐school level.
Digitale Zwillinge für Brücken mittlerer Stützweite – Pilotprojekt Brücke Schwindegg – Teil 2: Verwaltungsschale
Authors: Wimmer Johannes , Braml Thomas , Kaiser Maximilian 
Published: January 2024

AbstractDer Begriff „Digitaler Zwilling“ findet im deutschsprachigen Raum zunehmend Verwendung für die digitale Verwaltung und Überwachung des Zustands von Brücken. Während in der Industrie und Medizin bereits normative Entwicklungen für den Einsatz Digitaler Zwillinge angestoßen wurden, werden im Bauwesen derzeit erste Prototypen umgesetzt. Für den Betrieb digitaler Abbilder wurden proprietäre Onlineumgebungen entwickelt, die in ihrer Flexibilität und Wiederverwendbarkeit beschränkt sind. Eine Skalierung mittels Einbindung in Modelle des Building Information Modellings wird untersucht, stößt jedoch aufgrund der Echtzeitanbindung an ihre Grenzen. Im Beitrag werden bestehende Definitionen des Digitalen Zwillings der Industrie in den Kontext des Bauwesens gesetzt. Anhand der in Teil 1 des Beitrags vorgestellten Isenbrücke in Schwindegg wird die Implementierung dieser Brücke als Industrie 4.0‐Verwaltungsschale präsentiert. Es zeigt sich, dass auch für Ingenieurbauwerke ein industrieller datengetriebener Digitaler Zwilling technisch und semantisch umgesetzt werden kann. Im Beitrag werden außerdem zukünftige Herausforderungen für die Entwicklung von Auswertungs‐ und Steuermechanismen für das Bauwerk vorgestellt und eine Möglichkeit der Visualisierung gezeigt. Das Ziel ist die Schaffung einer Syntax für die Kommunikation zwischen den Verwaltungsschalen.