bluuebunny/crossref_metadata_2025_split huggingface dataset:
Childhood maltreatment, dissociation and borderline personality disorder: Preliminary data on the mediational role of mentalizing in complex post‐traumatic stress disorder
Authors: Bateman Anthony , Rüfenacht Eva , Perroud Nader , Debbané Martin , Nolte Tobias , Shaverin Lisa , Fonagy Peter 
Published: December 2023

AbstractObjectivesTreatments for borderline personality disorder (BPD) and post‐traumatic stress disorder (PTSD) are less effective for patients with co‐occurring symptoms of both disorders, who are considered to have complex PTSD (cPTSD), compared with patients with either condition alone. Evidence suggests that co‐occurrence of symptoms indicates greater impairment in mentalizing. This study examines evidence for targeting mentalizing when treating individuals with co‐occurring symptoms, irrespective of their exposure to developmental trauma and, for the first time, investigates the mediational role of mentalizing in the associations between BPD symptomatology and cPTSD.DesignWe identified in a routine clinical service a group of patients with BPD, with or without co‐occurring symptoms of PTSD. We hypothesized that patients with co‐occurring symptoms and a history of childhood maltreatment will show more severe clinical profiles and greater mentalizing problems, which in turn lead to symptoms consistent with cPTSD.MethodClinical profiles of 72 patients with BPD (43 with and 29 without co‐occurring symptoms of PTSD; mean age in both groups 28 years, 79% and 83% female, respectively) were identified using the Structured Clinical Interview for DSM‐IV Axis II Disorders. Patients completed self‐report measures of BPD and PTSD symptoms, well‐being, dissociation and reflective functioning. Childhood trauma histories were evaluated.ResultsCompared with patients with BPD‐only, those with co‐occurring BPD and PTSD showed greater severity in terms of BPD and dissociative symptoms, met a broader range of BPD diagnostic criteria, had a greater sense of personal worthlessness and self‐evaluated their well‐being as considerably diminished. This group was also more inclined to recall increased instances of childhood sexual abuse. In a mediation analysis, mentalizing acted as a partial mediator for the relationship between BPD severity and cPTSD, as well as between dissociative symptoms and cPTSD. Interestingly, mentalizing did not mediate the relationship between childhood sexual abuse and cPTSD.ConclusionsOverall, the correlational findings are consistent with an intended focus on mentalizing to treat cPTSD symptoms in individuals who also meet criteria for a diagnosis of BPD.
Revolutionizing carbon chemistry: Solar‐powered C(sp3)–N bond activation and CO2 transformation via newly designed SBE‐Y cutting‐edge dynamic photocatalyst
Authors: Shahin Rehana , Yadav Rajesh K. , Verma Rajesh K. , Singh Chandani , Singh Satyam , Kim Tae Wu , Gupta Navneet K. , Baeg Jin OoK 
Published: December 2023

AbstractA solvent‐free sulfur‐bridge‐eosin‐Y (SBE‐Y) polymeric framework photocatalyst was prepared for the first time through an in situ thermal polymerization route using elemental sulfur (S8) as a bridge. The addition of a sulfur bridge to the polymeric framework structure resulted in an allowance of the harvesting range of eosin‐Y (E‐Y) for solar light. This shows that a wider range of solar light can be used by the bridge material's photocatalytic reactions. In this context, supercharged solar spectrum: enhancing light absorption and hole oxidation with sulfur bridges. This suggests that the excited electrons and holes through solar light can contribute to oxidation–reduction reactions more potently. As a result, the photocatalyst‐enzyme attached artificial photosynthesis system developed using SBE‐Y as a photocatalyst performs exceptionally well, resulting in high 1,4‐NADH regeneration (86.81%), followed by its utilization in the exclusive production of formic acid (210.01 μmol) from CO2 and synthesis of fine chemicals with 99.9% conversion yields. The creation of more effective photocatalytic materials for environmental clean‐up and other applications that depend on the solar light‐driven absorption spectrum of inorganic and organic molecules could be one of the practical ramifications of this research.
Hyperexcitability of muscle spindle afferents in jaw‐closing muscles in experimental myalgia: Evidence for large primary afferents involvement in chronic pain
Authors: Sas Dar'ya , Gaudel Fanny , Verdier Dorly , Kolta Arlette 
Published: December 2023

AbstractThe goals of this review are to improve understanding of the aetiology of chronic muscle pain and identify new targets for treatments. Muscle pain is usually associated with trigger points in syndromes such as fibromyalgia and myofascial syndrome, and with small spots associated with spontaneous electrical activity that seems to emanate from fibers inside muscle spindles in EMG studies. These observations, added to the reports that large‐diameter primary afferents, such as those innervating muscle spindles, become hyperexcitable and develop spontaneous ectopic firing in conditions leading to neuropathic pain, suggest that changes in excitability of these afferents might make an important contribution to the development of pathological pain. Here, we review evidence that the muscle spindle afferents (MSAs) of the jaw‐closing muscles become hyperexcitable in a model of chronic orofacial myalgia. In these afferents, as in other large‐diameter primary afferents in dorsal root ganglia, firing emerges from fast membrane potential oscillations that are supported by a persistent sodium current (INaP) mediated by Na+ channels containing the α‐subunit NaV1.6. The current flowing through NaV1.6 channels increases when the extracellular Ca2+ concentration decreases, and studies have shown that INaP‐driven firing is increased by S100β, an astrocytic protein that chelates Ca2+ when released in the extracellular space. We review evidence of how astrocytes, which are known to be activated in pain conditions, might, through their regulation of extracellular Ca2+, contribute to the generation of ectopic firing in MSAs. To explain how ectopic firing in MSAs might cause pain, we review evidence supporting the hypothesis that cross‐talk between proprioceptive and nociceptive pathways might occur in the periphery, within the spindle capsule.
Discussion of Certain Problems in Regard to Marine Diesel Oil Engines
Authors: Anderson John W. 
Published: December 2023

Abstract
The methods of reversing as originally adopted in the German design for two-cycle engines and the method developed by an American firm for four-cycle engines, are discussed. A modification introduced in a two-cycle slow-speed engine used in a submarine tender proved satisfactory.
Diesel engines are usually started by means of compressed air; in small marine engines, a clutch between the engine and the propeller permits the independent starting of the engine. In all cases a smooth start is secured by bringing first the temperature in the cylinders to approximately the same value it has under working conditions. Regular turning moment and definite ignitions in the cylinders make possible the successful operation of a Diesel engine at slow speed. In the large sizes a smooth running at low speeds with light loads is obtained by a mechanism controlling the lift and timing of the spray valve.
While lubrication by gravity is used successfully in large open-frame slow-speed engines, the increasing adoption of forced lubrication in engines of all types and sizes is an evidence of the superior advantages of the latter system.
The satisfactory results given by the 2500-hp. six-cylinder two-cycle Diesel engines of the U. S. S. “Maumee” point out that all ocean-going cargo vessels can be equipped with Diesel engines.
Several features of the fuel system, the arrangement of the exhaust piping, the varieties of muffler, and the systems of cooling the various parts of Diesel engines, are considered from the point of view of the author’s experience.
Industrial Organization as it Affects Executives and Workers
Authors: Knoeppel Charles E. 
Published: December 2023

Abstract
The reconstruction of the world after so many years of war must be based on efficient industrial organization. The type of organization required should be established along sound lines from a proper consideration of individual relations between men.
The author, from a studious survey of his experience as an executive, emphasizes as essentials in the formulation of definite laws of organization: The necessity of having an objective in the mind before beginning to work; the exclusive concentration of each man to definite functions; the avoidance of confusion and conflict of authorities; the proper division of departments in order to insure that each executive has complete control of all the factors affecting the success of his function; the creation of divisions which will develop specialists; the provision for permanency by training men to fill the positions of their superiors; the exact definition of the duties of each employee and of his relations to the others; the logical selection of personnel according to individual qualifications; and the creation of a standard manufacturing practice.
Valuable suggestions are also given in regard to the question of establishing an efficient administration. Delegating authority to subordinates, overlooking minor details, listening to wise counsel and arousing initiative in employees are recommended as important points in the exercise of industrial authority.
Radiation Error in Measuring Temperature of Gases
Authors: Kreisinger Henry , Barkley J. F. 
Published: December 2023

Abstract
In measuring the temperature of a stream of hot gases surrounded by colder or hotter surfaces, heat radiates to or from the measuring instrument, making it read high or low, and the difference between the true temperature of the gases and that indicated by the instrument is called the radiation error.
The paper enumerates the factors with which this error varies, and to show the magnitude of the effects of some of them, gives results of a series of measurements made with thermocouples placed at different points along the paths of gases flowing through water-tube boilers, citing one instance where the error under certain conditions can be as much as 320 deg. cent.
A Foundation for Machine-Tool Design and Construction
Authors: De Leeuw A. L. 
Published: December 2023

Abstract
The author emphasizes the fact that engineering development has been most rapid in those branches which have had the assistance of mathematics and science. For example, the development of the steam engine in its first stages was slow and hesitating; but when the fundamental facts of thermodynamics were understood its progress became more rapid. It thus became possible to imagine a 100-per-cent-efficient engine working on an ideal cycle, with which the operative engine could be compared.
Similarly, in respect to machine tools, questions are enumerated upon which information is needed in order to follow the line of recent development of the steam engine. These relate particularly to the functions and action of the cutting tool, the action of the cutting lubricant, etc.
Experiments already made by the author are outlined and suggested lines of experimentation are indicated.
Bagasse as a Source of Fuel
Authors: Freeland E. C. 
Published: December 2023

Abstract
The heating value of one pound of average dry Louisiana bagasse is found by experiment to be 8300 B.t.u., and, despite a high moisture content of about 50 per cent, it is therefore a valuable fuel. While in former years not much attention was paid to the drying of bagasse before burning it, many authorities now claim that a great saving can be effected by such a procedure. The heating value of this important fuel to the sugar industry, as influenced by the high moisture content, and the benefits of preliminary drying are discussed at length, and notes are included on devices employed by various sugar houses in its use for steaming purposes.
Filter Approximations for Random Vibroacoustics of Rigid Porous Media
Authors: Sreekumar Abhilash , Kougioumtzoglou Ioannis A. , Triantafyllou Savvas P. 
Published: December 2023

Abstract
An approximate efficient stochastic dynamics technique is developed for determining response statistics of linear systems with frequency-dependent parameters, which are used for modeling wave propagation through rigid porous media subject to stochastic excitation. This is done in conjunction with a filter approximation of the system frequency response function. The technique exhibits the following advantages compared to alternative solution treatments in the literature. First, relying on an input–output relationship in the frequency domain, the response power spectrum matrix is integrated analytically for determining the stationary response covariance matrix, at zero computational cost. Second, the proposed filter approximation facilitates a state-variable formulation of the governing stochastic differential equations in the time domain. This yields a coupled system of deterministic differential equations to be solved numerically for the response covariance matrix. Thus, the nonstationary (transient) response covariance can be computed in the time domain at a relatively low computational cost. Various numerical examples are considered for demonstrating the accuracy and computational efficiency of the herein developed technique. Comparisons with pertinent Monte Carlo simulation (MCS) data are included as well.
Front Matter
Authors: Yeh Lian-Tuu 
Published: December 2023

This frontmatter contains the Table of Contents, List of Figures, Preface and About the Author. It is available for access by clicking on the PDF icon below.
eBook keywords: telecommunication equipment, component, printed circuit, joint thermal resistance, thermal interface materials, air cooling, heat sinks, system thermal analysis, liquid cooled systems, two phase heat transfer devices.
Germline testing ofBRCA1,BRCA2,PALB2andCHEK2c.1100delC in 1514 triple negative familial and isolated breast cancers from a single centre, with extended testing ofATM,RAD51CandRAD51Din over 400
Authors: Woodward Emma R , Lalloo Fiona , Forde Claire , Pugh Sarah , Burghel George J , Schlecht Helene , Harkness Elaine F , Howell Anthony , Howell Sacha J , Gandhi Ashu , Evans D Gareth 
Published: December 2023

BackgroundThe identification of germline pathogenic gene variants (PGVs) in triple negative breast cancer (TNBC) is important to inform further primary cancer risk reduction and TNBC treatment strategies. We therefore investigated the contribution of breast cancer associated PGVs to familial and isolated invasive TNBC.MethodsOutcomes of germlineBRCA1,BRCA2andCHEK2_c.1100delC testing were recorded in 1514 women (743—isolated, 771—familial), and forPALB2in 846 women (541—isolated, 305—familial), with TNBC and smaller numbers for additional genes. Breast cancer free controls were identified from Predicting Risk Of Cancer At Screening and BRIDGES (Breast cancer RIsk after Diagnostic GEne Sequencing) studies.ResultsBRCA1_PGVs were detected in 52 isolated (7.0%) and 195 (25.3%) familial cases (isolated—OR=58.9, 95% CI: 16.6 to 247.0),BRCA2_PGVs in 21 (2.8%) isolated and 67 (8.7%) familial cases (isolated—OR=5.0, 95% CI: 2.3 to 11.2),PALB2_PGVs in 9 (1.7%) isolated and 12 (3.9%) familial cases (isolated—OR=8.8, 95% CI: 2.5 to 30.4) andCHEK2_c.1100delC in 0 isolated and 3 (0.45%) familial cases (isolated—OR=0.0, 95% CI: 0.00 to 2.11).BRCA1_PGV detection rate was >10% for all familial TNBC age groups and significantly higher for younger diagnoses (familial: <50 years, n=165/538 (30.7%); ≥50 years, n=30/233 (12.9%); p<0.0001). Women with a G3_TNBC were more likely to have aBRCA1_PGV as compared with aBRCA2orPALB2_PGV (p<0.0001). 0/743 isolated TNBC had theCHEK2_c.1100delC PGV and 0/305 anyATM_PGV, but 2/240 (0.83%) had aRAD51D_PGV.ConclusionPGVs inBRCA1are associated with G3_TNBCs. Familial TNBCs and isolated TNBCs <30 years have a >10% likelihood of a PGV inBRCA1. BRCA1_PGVs are associated with younger age of familial TNBC. There was no evidence for any increased risk of TNBC withCHEK2orATMPGVs.
A Novel Ensemble Model for Brain Tumor Diagnosis
Authors: Talaat Amira Samy 
Published: December 2023

The spread of brain tumors resulted in numerous deaths, and cancer patients are still being treated. Four novel models are introduced and compared in this study. The best one is the PIEnsemble model, which was created to correctly identify and classify MRI images for brain tumor classification. The PIEnsemble primarily combines three deep learning techniques, ResNet Model, GoogleNet Model, and Inception Model, integrated with two dimensionality reduction techniques, PCA and ICA, which are used for feature extraction with a combination of Linear, Batch1Norm1D, and ReLU layers. Simulations in a series on two benchmarks datasets were run to show the improved effectiveness of the PIEnsemble model. The experimental results highlighted the improvements to the PIEnsemble classifier structure, which has the highest classification accuracy ratio and superior performance to other methods, with a 98.25% accuracy for Dataset 1 and a 98.75% accuracy for Dataset 2.
Spin–Orbit Torque and Geometrical Backscattering
Authors: Tan Seng Ghee , Huang Che-Chun , Jalil Mansoor B. A. , Chang Ching-Ray , Cheng Szu-Cheng 
Published: December 2023

We show in this paper that the technologically relevant field-like spin–orbit torque (SOT) shows resilience against the geometrical effect of electron backscattering. As a device grows smaller in size, the effect of geometry on physical properties like spin torque, and hence switching current could place a physical limit on the continued shrinkage of such a device — a necessary trend of all memory devices (MRAM). The geometrical effect of curves has been shown to impact quantum transport and topological transition of Dirac and topological systems. In our work, we have ruled out the potential threat of line curves degrading the effectiveness of SOT switching. In other words, SOT switching will be resilient against the influence of curves that line the circumferences of defects in the events of electron backscattering, which commonly happens in the channel of modern electronic devices.
Tumor-Specific Activity of Precision Medicines in the NCI-MATCH Trial
Authors: Zhou Ivvone , Plana Deborah , Palmer Adam C. 
Published: December 2023

Abstract

Purpose:
National Cancer Institute Molecular Analysis for Therapy Choice (NCI-MATCH) is a precision medicine basket trial designed to test the effectiveness of treating cancers based on specific genetic changes in patients’ tumors, regardless of cancer type. Multiple subprotocols have each tested different targeted therapies matched to specific genetic aberrations. Most subprotocols exhibited low rates of tumor shrinkage as evaluated across all tumor types enrolled. We hypothesized that these results may arise because these precision cancer therapies have tumor type-specific efficacy, as is common among other cancer therapies.

Experimental Design:
To test the hypothesis that certain tumor types are more sensitive to specific therapies than other tumor types, we applied permutation testing to tumor volume change and progression-free survival data from 10 published NCI-MATCH subprotocols (together n = 435 patients). FDR was controlled by the Benjamini–Hochberg procedure.

Results:
Six of ten subprotocols exhibited statistically significant evidence of tumor-specific drug sensitivity, four of which were previously considered negative based on response rate across all tumors. This signal-finding analysis highlights potential uses of FGFR tyrosine kinase inhibition in urothelial carcinomas with actionable FGFR aberrations and MEK inhibition in lung cancers with BRAF non-V600E mutations. In addition, it identifies low-grade serious ovarian carcinoma with BRAF v600E mutation as especially sensitive to BRAF and MEK co-inhibition (dabrafenib plus trametinib), a treatment that received accelerated FDA approval for advanced solid tumors with BRAF v600E mutation.

Conclusions:
These findings support the value of basket trials because even when precision medicines do not have tumor-agnostic activity, basket trials can identify tumor-specific activity for future study.
Civil Society Perspectives on Rights and Freedoms in the Association of Southeast Asian Nations
Authors: Chaney Paul 
Published: December 2023

Abstract
This pan-regional analysis of non-governmental organisations’ (NGO) perspectives on the contemporary factors which constrain or repress civil society in the Association of Southeast Asian Nations (ASEAN) is based on United Nations’ Universal Periodic Review (UPR) data. It shows that, paradoxically, whilst the majority of ASEAN states have ratified the International Covenant on Civil and Political Rights (ICCPR) that upholds civil society’s political role in promoting rights and democracy, this is inimical to the region’s political elites who regard civil society’s primary function as non-political delivery of social welfare and development. This disjuncture results in repression, performativity, and legitimation. The UPR data reveal an ever-shrinking civil space. Civil society, including human rights defenders (HRD s), faces a raft of rights pathologies, including threats, violence and murder—as well as increasing state restrictions on freedom of association and expression. This is compounded by impunity for offenders, corruption, and government inaction following earlier UPR recommendations.
The Hijab Ban Verdict: A Case Note on Aishat Shifat v. The State of Karnataka
Authors: Sinha Navin , Dutta Mitul 
Published: December 2023

Abstract
Should judges engage in theological deliberations? This question has often been asked in the context of religious claims before the courts in India. Following the hijab ban by the Karnataka government, the subsequent decision of the Karnataka High Court (khc) upholding it, and a split verdict by the Supreme Court of India (sci), the question is doing the rounds once again. The present article attempts to critically analyze the decisions of the khc and the sci on the hijab controversy. The analysis draws on the claim of Justice Dhulia that the courts are not the proper forum to engage in theological deliberations, and judicial interference is warranted only when the limits set by the Constitution are violated. In alignment with the claims of Justice Dhulia, the present article argues that in matters concerning government interference in religious practices, the focus of the reviewing court should be more on the legitimacy of the restriction rather than the religious validity of the practice. The author agrees with Justice Dhulia that in matters concerning the right to religion, proportionality is objectively the better standard of judicial review, as it dissuades the court from inquiring into the religious and cultural practices of the parties.
Choices and Allocation of Costs for Religious Preferences and Practices: Insights from an Israeli Test Case
Authors: Israel-Vleeschhouwer Amos 
Published: December 2023

Abstract
Internalization of costs of religious preferences fits the religious self-perception and ideology of many religious communities and is in their long-term interest. It also strengthens the external value of religious communities, norms, and institutions for the wider society.
Many forces press religious communities to reduce the costs of religious preferences. Within a community, costs are reduced by limiting the available choices or shifted to its weaker members; outside the community, costs are shifted to other groups or the state. Incentives influence the allocation of costs, which in turn shape internal communal choices and the religious vitality and sustainability of the community. The allocation of costs also affects the external relations of communities. This article suggests that the allocation of costs is yet another aspect of religious and ideological communities in liberal states that deserves investigation at the constitutional, legal, and regulatory levels.