bluuebunny/crossref_metadata_2025_split huggingface dataset:
Polymer‐Grafting from MOF Nanosheets for the Fabrication of Versatile 2D Materials
Authors: Ye Siyuan , Hosono Nobuhiko , Uemura Takashi 
Published: November 2023

AbstractTwo‐dimensional (2D) materials based on metal‐organic framework (MOF) nanosheets are highly useful for electronic devices, catalysis, and energy storage systems because of their high structural designability and anisotropy. However, their high surface energy often causes aggregation and low dispersibility, which reduces their processability and performance. To address these fundamental issues, it is reported a new approach involving polymer grafting from the surfaces of MOF nanosheets. A newly discovered one‐step synthetic pathway provides MOF nanosheets functionalized with a polymerization initiator agent on the surface with over 90% yield. Successive nitroxide‐mediated living polymerization of vinyl monomers from the MOF nanosheet surfaces provides polymer‐grafted nanosheets with superior dispersibility in many organic solvents. The polymer‐decorated MOF nanosheets exhibit versatile property modulation, which allows for their protection and efficient use in applications such as photoredox catalysts and oil/water separation membranes. This polymer‐grafting approach can facilitate the fabrication of surface‐functionalized MOF nanosheets, which can lead to the wider application of 2D materials in various fields.
21.41%‐Efficiency CsPbI3 Perovskite Solar Cells Enabled by an Effective Redox Strategy with 4‐Fluorobenzothiohydrazide in Precursor Solution
Authors: Duan Yuwei , Wang Jungang , Xu Dongfang , Ji Peigen , Zhou Hui , Li Yong , Yang Shaoming , Xie Zhuang , Hai Xiaohu , Lei Xuruo , Sun Rui , Fan Zihao , Zhang Ke , Liu Shengzhong , Liu Zhike 
Published: November 2023

AbstractTo simultaneously stabilize cesium lead triiodide (CsPbI3) precursor solution and passivate the defects in CsPbI3 film is greatly significant for achieving highly stable and efficient CsPbI3 perovskite solar cells (PSCs). Herein, an effective redox 4‐fluorobenzothiohydrazide (FBTH) is developed to stabilize the precursor solution and passivate iodine/lead‐related defects for high‐quality CsPbI3 film. The comprehensive research confirms that 1) a new compound FBTH‐I is obtained from an effective redox interaction between FBTH and molecular iodine (I2) in perovskite precursor solution, which can effectively impede the formation of I2 molecule and restrain I− migration in perovskite film by forming N–H···I bond; 2) FBTH‐I can also passivate Pb‐related defects via forming S···Pb interaction. Consequently, the CsPbI3 PSC based on FBTH‐treated precursor solution exhibits a fascinating power conversion efficiency (PCE) of 21.41%, which is one of the highest PCE values among the reported pure CsPbI3 PSCs so far, and an outstanding stability against the harsh conditions, such as thermal annealing and continuous light‐illumination.
Hollow Cavity CaO2@Polydopamine Nanocomposites for pH‐Responsive Ca2+‐Enhanced Efficient Mild Hyperthermia in the NIR‐II Region
Authors: Wang Yue , Wang Shuqi , Li Shanshan , Zhen Wenyao , Jia Xiaodan , Jiang Xiue 
Published: November 2023

AbstractSecond near‐infrared (NIR‐II) mild photothermal therapy with higher tissue penetration depth and less damage to healthy tissues is emerging as an attractive antitumor modality, but its therapeutic efficiency is dramatically suppressed by the resistance of heat shock proteins (HSPs). As a widely explored photothermal agent, the application of polydopamine (PDA) in the NIR‐II region is hampered by low photothermal conversion efficiency (PCE). Herein, its PCE in the NIR‐II region is improved by developing novel hollow cavity CaO2@PDA nanocomposites through chelation‐induced diffusion of inner core Ca2+ to the shell PDA to facilitate multiple reflections of laser in the cavity. Upon pH‐responsive degradation of CaO2, its structure is transformed into a stacked “nano‐mesh” with excellent light absorption and an enlarged effective irradiation area. Overloading of Ca2+ ions not only induces downregulation of HSPs but also enhances interference of light on membrane potential, which further aggravate mitochondrial dysfunction and reduce the thermotolerance of tumor cells, promoting efficient mild hyperthermia of PDA in the NIR‐II region.
Seconds Timescale Synthesis of Highly Stretchable Antibacterial Hydrogel for Skin Wound Closure and Epidermal Strain Sensor
Authors: Bi Yanni , Sun Mimi , Zhang Yuanyuan , Sun Fuxin , Du Yan , Wang Jingjuan , Zhou Ming , Ma Chong‐Bo 
Published: November 2023

AbstractEffective wound healing is critical for patient care, and the development of novel wound dressing materials that promote healing, prevent infection, and are user‐friendly is of great importance, particularly in the context of point‐of‐care testing (POCT). This study reports the synthesis of a hydrogel material that can be produced in less than 10 s and possesses antibacterial activity against both gram‐negative and gram‐positive microorganisms, as well as the ability to inhibit the growth of eukaryotic cells, such as yeast. The hydrogel is formed wholly based on covalent‐like hydrogen bonding interactions and exhibits excellent mechanical properties, with the ability to stretch up to more than 600% of its initial length. Furthermore, the hydrogel demonstrates ultra‐fast self‐healing properties, with fractures capable of being repaired within 10 s. This hydrogel can promote skin wound healing, with the added advantage of functioning as a strain sensor that generates an electrical signal in response to physical deformation. The strain sensor composed of a rubber shell realizes fast and responsive strain sensing. The findings suggest that this hydrogel has promising applications in the field of POCT for wound care, providing a new avenue for improved patient outcomes.
Microphase‐Separated Elastic and Ultrastretchable Ionogel for Reliable Ionic Skin with Multimodal Sensation
Authors: Lv Dong , Li Xin , Huang Xin , Cao Chunyan , Ai Liqing , Wang Xuejiao , Ravi Sai Kishore , Yao Xi 
Published: November 2023

AbstractBioinspired artificial skins integrated with reliable human‐machine interfaces and stretchable electronic systems have attracted considerable attention. However, the current design faces difficulties in simultaneously achieving satisfactory skin‐like mechanical compliance and self‐powered multimodal sensing. Here, this work reports a microphase‐separated bicontinuous ionogel which possesses skin‐like mechanical properties and mimics the multimodal sensing ability of biological skin by ion‐driven stimuli‐electricity conversion. The ionogel exhibits excellent elasticity and ionic conductivity, high toughness, and ultrastretchability, as well as a Young's modulus similar to that of human skin. Leveraging the ion‐polymer interactions enabled selective ion transport, the ionogel can output pulsing or continuous electrical signals in response to diverse stimuli such as strain, touch pressure, and temperature sensitively, demonstrating a unique self‐powered multimodal sensing. Furthermore, the ionogel‐based I‐skin can concurrently sense different stimuli and decouple the variations of the stimuli from the voltage signals with the assistance of a machine‐learning model. The ease of fabrication, wide tunability, self‐powered multimodal sensing, and the excellent environmental tolerance of the ionogels demonstrate a new strategy in the development of next‐generation soft smart mechano‐transduction devices.
Efficient Photothermal Anti‐/Deicing Enabled by 3D Cu2‐xS Encapsulated Phase Change Materials Mixed Superhydrophobic Coatings
Authors: Hou Mingtai , Jiang Zeyi , Sun Wen , Chen Zhenghao , Chu Fuqiang , Lai Nien‐Chu 
Published: November 2023

AbstractPhotothermal superhydrophobic surfaces are one of the most promising anti‐/deicing materials, yet they are limited by the low energy density and intermittent nature of solar energy. Here, a coupling solution based on microencapsulated phase change materials (MPCMs) that integrates photothermal effect and phase change thermal storage is proposed. Dual‐shell octahedral MPCMs with Cu2O as the first layer and 3D Cu2‐xS as the second layer for the first time is designed. By morphology and phase manipulation of the Cu2‐xS shell, the local surface plasmonic heating modulation of MPCMs is realized, and the MPCM reveals full‐spectrum high absorption with a photothermal conversion efficiency up to 96.1%. The phase change temperature and enthalpy remain in good consistency after 200 cycles. Multifunctional photothermal phase‐change superhydrophobic composite coatings are fabricated by combining the hydrolyzed and polycondensation products of octadecyl trichlorosilane and the dual‐shell MPCM. The multifunctional coatings exhibit excellent anti‐/deicing performance under low temperature and high humidity conditions. This work not only provides a new approach for the design of high‐performance MPCMs but also opens up an avenue for the anti‐icing application of photothermal phase‐change superhydrophobic composite coatings.
Bismuth and Chlorine Dual‐Doped Perovskite Chloride as a Phase‐Structure‐Stable and Moisture‐Resistant Solid Electrolyte for Chloride Ion Batteries
Authors: Xia Tianchen , Li Qiang , Zhao Xiangyu , Shen Xiaodong 
Published: November 2023

AbstractPerovskite chloride, an anion conductor, is a promising candidate to be a solid electrolyte for high‐energy and sustainable chloride ion batteries (CIB). However, it suffers from poor structural stability at low temperature and in ambient conditions, which leads to its transformation from an ionic conductor to an insulator. Herein, a bismuth and chlorine dual doping strategy is developed to stabilize the cubic structure of CsSnCl3 in harsh environments. The as‐prepared dual‐doped CsSn0.9Bi0.1Cl3.1 material with an optimized composition maintains its cubic structure at the extremely low temperature of 213 K for 10 days and at 40% relative humidity for 50 days, while the undoped cubic material deteriorates and transforms to a monoclinic phase under these conditions in less than 1 day. Consequently, the dual doping achieves efficient chloride ion conduction that is superior to single bismuth doping due to the introduction of interstitial chlorine facilitating chloride ion transport. Importantly, the practicality of the as‐prepared solid electrolyte is demonstrated in different symmetric solid cells and by various CIBs using the organic electrode couple, a multivalent metal chloride cathode, or a new high‐voltage metal oxychloride cathode.
Total Synthesis of Laetevirenol A via Regioselective Gold‐Catalyzed and Acid‐Promoted Cyclizations
Authors: Milián Ana , Sánchez‐Jiménez Lucía , Tostado Jaime , Vaquero Juan J. , Fernández‐Rodríguez Manuel A. , García‐García Patricia 
Published: November 2023

AbstractThe total synthesis of Laetevirenol A, a natural product with antioxidant activity, has been achieved. A gold‐catalyzed cycloisomerization of an o‐alkenyl‐o’‐alkynylbiphenyl has been used as the key step for the construction of the phenanthrene moiety present in Laetevirenol A. Several studies in model substrates have been carried out to unveil the effect of substituents in different locations in the outcome of this cyclization, which allowed the design of an appropriate precursor for the fundamental gold‐catalyzed cycloisomerization. The suitably functionalized phenanthrene intermediate obtained in this key step could be further transformed into Laetevirenol A via a Friedel‐Crafts cyclization, which also turned out to be dependent on the nature of the substituents. Finally, Laetevirenol A was obtained in 10 steps from commercially available substrates, with a 20% global yield.
Synthesis of novel biphenyl‐fused alicyclic tetracarboxylic dianhydride and its performance in thermostable and transparent colorless polyimides
Authors: Zhou Di , Kong Ling‐lu , Liu Shu‐mei , Yuan Yan‐chao , Ma Yu‐guang , Huang Ming‐jun , Mo Yue‐qi , Qin Dong‐huan , Zhao Jian‐qing 
Published: November 2023

AbstractBiphenyl fused alicyclic tetracarboxylic dianhydride, 6,6′,7,7′‐tetracarboxylic dianhydride‐5,5′,6,6′,7,7′,8,8′‐octahydro‐2,2′‐binaphthalene (OHBNDA) was successfully synthesized from biphenyltetracarboxylic dianhydride (BPDA) through hydrolysis, reduction, bromination, and Diels–Alder reaction. Three OHBNDA‐based polyimides (PIs) were synthesized by one‐step polycondensation at high temperature with 9,9‐bis(4‐aminophenyl)fluorene (BAFL), 2,2′‐bis(trifluoromethyl)‐4,4′‐diaminobiphenyl (TFMB), and 4,4′‐diamino‐2,2′‐dimethyl‐1,1′‐biphenyl (m‐TolDA) diamines, respectively. These PIs have moderate molecular weights and good solubility in polar organic solvents, such as N,N‐dimethylformamide, dimethylacetamide (DMAc), and dimethyl sulfoxide (DMSO). OHBNDA‐TFMB, OHBNDA‐m‐TolDA, and OHBNDA‐BAFL display glass transition temperatures (Tgs) of 309, 329, and 377°C from differential scanning calorimetry (DSC) curves, and the decomposition temperatures at 5% weight loss (Td5) of as high as 522, 507, and 548°C under nitrogen, respectively. Meanwhile, these PI films also show good optical transparency with the cut‐off wavelength <315 nm and the transmittance >75% at 400 nm. These results confirm that aryl‐fused alicyclic tetracarboxylic dianhydrides can afford transparent/colorless PIs with high thermal stability, especially the higher decomposition temperatures than the wholly alicyclic dianhydrides.
Repurposing endogenous type II CRISPR‐Cas9 system for genome editing in Streptococcus thermophilus
Authors: Ma Shuai , Wang Feiyu , Xuejing Zhang , Liping Qiao , Xueping Guo , Lu Xuemei , Qi Qingsheng 
Published: November 2023

AbstractStreptococcus thermophilus has been extensively used in industrial milk fermentation. However, lack of efficient genetic manipulation approaches greatly hampered the industrial application of this species. Here, we repurposed the endogenous CRISPR1 and CRISPR3 systems, both belong to type II‐A CRISPR‐Cas9, by delivering a self‐targeting CRISPR array with DNA repair template into S. thermophilus LMD‐9. We achieved 785‐bp deletion in lacZ gene by repurposing CRISPR1 and CRISPR3 systems with efficiencies of 35% and 59%, respectively, when 1‐kb DNA repair template was provided. While providing with 1.5‐kb repair template, the editing efficiency for deletion in lacZ gene reached 90% using CRISPR3 systems. Diverse editing outcomes encompassing a stop code insertion and single nucleotide variation within lacZ, as well as a 234‐bp DNA fragment insertion upstream of ster_0903, were generated with high efficiencies of 75%–100% using the CRISPR3 system. Harnessing the customized endogenous CRISPR3 system to target six genes of eps gene cluster, we obtained six single‐gene knockout mutants with efficiencies of 29%–80%, and proved that the epsA, epsE, and epsG were the key genes affecting exopolysaccharides biosynthesis in S. thermophilus LMD‐9. Altogether, repurposing the native type II‐A CRISPR‐Cas9 can be served as a toolkit for precise genome engineering in S. thermophilus for biotechnological applications.
Development of a nutritional screening and assessment indicator system for patients with esophageal cancer in China: Findings from the Delphi method
Authors: Shang Jingjing , Dong Wen , Huang Peipei , Sun Yidan , He Yuxin , Li Hui , Liao Shengwu , Li Mei 
Published: November 2023

AbstractBackgroundIn China, individuals diagnosed with esophageal cancer are confronted with an elevated risk of nutritional inadequacy or malnutrition throughout the course of their disease, a condition that contributes to various adverse clinical outcomes. A vast corpus of data are burgeoning at an unprecedented rate, primarily due to the revolutionary growth of digitalization technologies and artificial intelligence, notably within the domains of health care and medicine. The purpose of this investigation is to initiate the development of a nutritional screening and assessment indicator framework for patients with esophageal cancer within the Chinese context. We seek to furnish an instrumental reference to facilitate preparations for the forthcoming era of advanced, “deep,” evidence‐based medicine.MethodsAn integrative methodology was employed to forge the preliminary draft of the nutritional screening and assessment indicator system for preoperative patients with esophageal cancer. This encompassed a rigorous literature survey, in‐depth clinical practice investigation, and the facilitation of expert panel discussions. Thereafter, two iterative consultation phases were conducted using the Delphi method in China. The analytic hierarchy process was deployed to ascertain the weighting of each index within the definitive evaluation indicator system.ResultsThe effective response rates for the dual rounds of expert consultation were 91.7% and 86.4%, with commensurate authority coefficients of 0.97 and 0.91. The Kendall harmony coefficients were ascertained to be 0.19 and 0.14 (p < 0.01), respectively. The culminating nutritional screening and assessment indicator system for patients with esophageal cancer comprised 5 primary‐level indicators and 38 secondary‐level indicators.ConclusionsThe nutritional screening and assessment indicator system contrived for patients with esophageal cancer is underpinned by cogent theoretical principles, leverages an astute research methodology, and manifests dependable outcomes. This system may be appositely utilized as a meaningful reference for the nutritional screening and assessment process in patients afflicted with esophageal cancer.
Artificial intelligence integration in counsellor education and supervision: A roadmap for future directions and research inquiries
Authors: Maurya Rakesh K. , DeDiego Amanda C. 
Published: November 2023

AbstractThis article explores the evolving landscape of artificial intelligence (AI) integration in counsellor education and supervision, presenting a roadmap for future research inquiries. The article underscores the need for future research to critically examine the ethical and beneficial integration of AI in counsellor education, focusing on training programmes and guidelines. Additionally, it calls for the development of comprehensive frameworks for AI chatbot integration, supervision models for counsellors‐in‐training and further exploration of AI's potential in the counselling profession. In conclusion, while advanced conversational AI shows promise in counselling, more research is needed to ensure responsible and effective integration. This article provides valuable insights and directions for future investigations, aiming to shape the ethical use of AI technologies in the counselling field.
A Review of the Ethnomedicinal, Phytochemical, and Anticancer Properties of Melicope Species
Authors: Adewale Ahmed Idris , Hossain Md. Sanower , Pei Cee Lim , Hisam Zamakshsharia Nor 
Published: November 2023

AbstractThe genus Melicope, which consists of 230 species, stands out as the largest genus within the Rutaceae family. Melicope species are characterized by their evergreen nature and can range from shrubs to predominantly dioecious trees. The Melicope species have been utilized in traditional medicine to address a wide range of ailments, including fever, colds, cramps, and inflammation. These plants have gained significant attention due to their noteworthy ethnopharmacological and ethnomedicinal significance. Researchers have isolated numerous biologically active secondary metabolites from different Melicope species, which include polymethoxylated flavonoids, furanocoumarins, acetophenones, benzenoids, and quinolone alkaloids. These compounds exhibit diverse biological activities, such as antibacterial, antidiabetic, antifungal, and antiproliferative properties against human cancer cell lines. This review provides an update on the chemical constituents of the selected species of Melicope. The study also highlights the anticancer and cytotoxicity properties of the plant extracts and phytochemical constituents from Melicope species. Furthermore, the molecular mechanisms underlying the anticancer effects are elucidated. Overall, this review contributes to understanding the significant pharmacological potential of Melicope species and unlocking their chemical composition, emphasizing their relevance in the development of therapeutic agents, particularly in the field of cancer research.
Unraveling the influence of human capital and stakeholder engagement on corporate digital responsibility: Implications for firm performance in Southeast Asia enterprises
Authors: Vo Thai Huy‐Cuong , Hue Trinh Hoang Hong , Chen Pei‐fen , Tran My‐Linh 
Published: November 2023

AbstractSoutheast Asian enterprises (SAEs) face the challenge of ensuring responsible and ethical utilization of data and digital technologies in the rapidly evolving digital landscape. Corporate digital responsibility (CDR) has emerged as a framework to guide organizations in adopting socially, economically, technologically, and ecologically responsible practices. However, empirical research on CDR is limited, highlighting the need for further investigation to bridge the gap between theory and practice. This study addresses this gap by examining the influence of human capital and stakeholder engagement on the formulation and execution of CDR strategies and their impact on firm performance. Drawing upon the theoretical framework of a Resource‐Based View and analyzing data from 2106 enterprises in Vietnam, Philippines, and Indonesia were collected through the Future of Business Survey. This research contributes insights into the drivers and determinants of CDR adoption and implementation, evaluates the effectiveness of different CDR approaches in achieving favorable post‐CDR performance outcomes, emphasizes the moderating role of stakeholder engagement, and offers a unique empirical perspective within the context of SAEs. This study enriches our understanding of CDR and provides practical implications for organizations seeking to navigate the complexities of responsible digital practices.
Aerobic Oxidation of 5‐Hydroxymethylfurfural via Hydrogen Bonds Reconstruction with Ternary Deep Eutectic Solvents
Authors: Chu Fuhao , Lu Bo , Zhao Guiyi , Zhu Zhiguo , Yang Kaixuan , Su Ting , Zhang Qiaohong , Chen Chen , Lü Hongying 
Published: November 2023

AbstractHydrogen bonding effect exists widely in various chemical and biochemical systems, primarily stabilizing the molecular structure as a positive factor. However, the presence of intermolecular hydrogen bonds among biomass molecules results in a formidable challenge for the efficient utilization of biomass resources. Here in, a novel strategy of “hydrogen bonds reconstruction” was developed by a series of ternary deep eutectic solvent (DESs) as molecular scissors, which disrupting the initial intermolecular hydrogen bonds and reconstructing the new ones to increase the reactivity of the biomass‐based compound. The DESs played a crucial role in enhancing the reactivity of 5‐hydroxymethylfurfural (HMF) and promoting its oxidation through reconstructing the hydrogen bonds interactions. Furthermore, DESs was also found to activate the Anderson‐type catalyst Na5IMo6O24 (IMo6) through an electron‐transfer mechanism, which facilitated the generation of oxygen vacancies and significantly enhances its ability to activate molecular oxygen. With this novel catalytic system, oxidation of HMF exhibited remarkable efficiency as HMF was almost entirely converted into FFCA with an impressive yield of 98 % under the optimized conditions. This finding offers novel insights into the utilization of biomass resources and endows the solvent with new functions in the chemical reaction.