bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical impact and characteristics of erythroid dysplasia in adult aplastic anaemia: Results from a multicentre registry
Authors: Maeda Tomoya , Matsuda Akira , Kanda Junya , Kawabata Hiroshi , Ishikawa Takayuki , Tohyama Kaoru , Kitanaka Akira , Araseki Kayano , Shimbo Kei , Hata Tomoko , Suzuki Takahiro , Kayano Hidekazu , Usuki Kensuke , Shindo‐Ueda Maki , Arima Nobuyoshi , Nohgawa Masaharu , Ohta Akiko , Chiba Shigeru , Miyazaki Yasushi , Nakao Shinji , Ozawa Keiya , Arai Shunya , Kurokawa Mineo , Takaori‐Kondo Akifumi , Mitani Kinuko ,   the Japanese National Research Group on Idiopathic Bone Marrow Failure Syndromes
Published: February 2024

SummaryMorphological dysplasia in haematopoietic cells, defined by a 10% threshold in each lineage, is one of the diagnostic criteria for myelodysplastic neoplasms. Dysplasia limited to the erythroid lineage has also been reported in some cases of aplastic anaemia (AA); however, its significance remains unclear. We herein examined the impact of erythroid dysplasia on immunosuppressive therapy responses and survival in AA patients. The present study included 100 eligible AA patients without ring sideroblasts. Among them, 32 had dysplasia in the erythroid lineage (AA with minimal dysplasia [mini‐D]). No significant sex or age differences were observed between AA groups with and without erythroid dysplasia. In severe/very severe AA and non‐severe AA patients, a response to anti‐thymocyte globulin + ciclosporin within 12 months was observed in 80.0% and 60.0% of AA with mini‐D and 42.9% and 90.0% of those without dysplasia, with no significant difference (p = 0.29 and p = 0.24 respectively). Overall survival and leukaemia‐free survival did not significantly differ between the groups. Collectively, the present results indicate that the presence of erythroid dysplasia did not significantly affect clinical characteristics or outcomes in AA patients, suggesting that its presence in AA is acceptable. Therefore, erythroid dysplasia should not exclude an AA diagnosis.
Cardiac events in newly diagnosed acute myeloid leukaemia during treatment with venetoclax + hypomethylating agents
Authors: Johnson Isla M. , Karrar Omer , Rana Masooma , Iftikhar Moazah , Chen Sunny , McCullough Kristen , Saliba Antoine N. , Al‐Kali Aref , Alkhateeb Hassan , Begna Kebede , Litzow Mark , Hogan William J. , Shah Mithun , Patnaik Mrinal M. , Pardanani Animesh , Hermann Joerg , Tefferi Ayalew , Gangat Naseema 
Published: February 2024

SummaryAmong 301 newly diagnosed patients with acute myeloid leukaemia receiving venetoclax and a hypomethylating agent, 23 (7.6%) experienced major cardiac complications: 15 cardiomyopathy, 5 non‐ST elevation myocardial infarction and/or 7 pericarditis/effusions. Four patients had more than one cardiac complication. Baseline characteristics included median age ± interquartile range; 73 ± 5 years; 87% males; 96% with cardiovascular risk factors; and 90% with preserved baseline ejection fraction. In multivariate analysis, males were more likely (p = 0.02) and DNMT3A‐mutated cases less likely (p < 0.01) to be affected. Treatment‐emergent cardiac events were associated with a trend towards lower composite remission rates (43% vs. 62%; p = 0.09) and shorter survival (median 7.7 vs. 13.2 months; p < 0.01). These observations were retrospectively retrieved and warrant further prospective examination.
A survey on service users' perspectives about information and shared decision‐making in psychotropic drug prescriptions in people with intellectual disabilities
Authors: de Kuijper Gerda , Jonker Josien , Sheehan Rory , Hassiotis Angela 
Published: February 2024

AbstractBackgroundIn people with intellectual disabilities and mental disorders and/or challenging behaviours, rates of psychotropic drug prescription are high. In clinical treatments and evaluations, all stakeholders should be involved in a process of shared decision‐making (SDM). We aimed to investigate the perspectives of clients and their carers on clients’ treatments with psychotropic drugs.MethodsWe conducted a survey among adults with intellectual disabilities in a Dutch mental healthcare centre providing community, outpatient and inpatient care. Data were collected between January and June 2022. Questions focused on experiences with the provision of information, treatment involvement and SDM and participants' wishes in this regard.FindingsRespondents (57 clients and 21 carers) were largely satisfied with the overall care from their clinicians, and with how information on the pharmacological treatment was provided verbally, but written information was insufficient or not provided. Seventy per cent of clients and 60% of carers reported being involved in medication decision‐making. However, over 75% of participants desired greater involvement in SDM and over 60% in medication reviews.ConclusionsService users and representatives were satisfied about the treatment and verbal information on their psychotropic drug use. The provision of written information, the SDM process and ongoing evaluation of psychotropic medication use could be improved.
Gender equity and male and female smoking behavior
Authors: Jergins William 
Published: February 2024

AbstractWe document a positive relationship between culturally inherited beliefs about gender equity and female smoking, using data on first and second‐generation immigrants living in the United States. We find that a one standard deviation increase in our measure of gender equity is associated with an increase in the probability that a female immigrant smokes of approximately 1.4 and 1.8 percentage points or 23% and 20% for first and second‐generation immigrants respectively. As male smoking behavior is largely unaffected by gender equality, we find that gender equity tends to reduce the size of the gender gap in smoking.
Female stereotypes and female empowerment in advertising: A systematic literature review and future research agenda
Authors: Gomez‐Borquez Claudia L. , Török Anna , Centeno‐Velázquez Edgar , Malota Erzsébet 
Published: February 2024

AbstractThis systematic literature review (SLR) seeks to foster the presence of feminism and women's diversity in advertising through a systematic, transparent, and rigorous framework‐based review and the 4Ws1H (What, Where, Why, and HoW) analysis. The study provides three main contributions. First, it offers an innovative conceptual framework for examining female stereotypes and female empowerment in advertising by categorizing the 21st‐century literature into the four evolutive eras of feminism: prefeminism, feminism, postfeminism, and the fourth wave of feminism. Second, this SLR reveals prevailing research trends, predominant research methodologies, frequently explored geographical regions, and industries of focus while providing a roadmap for future research endeavors. Finally, it acknowledges the lasting impact of femvertising as a response to consumer demands during the fourth wave of feminism and its role in promoting diversity and inclusion in advertising, encompassing disabilities, ethnicity, age, and gender identity. The main research trends uncovered in this study encompass the effects of female stereotypes, the sexualization of women in advertising, attitudes related to the brand, and the exploration of female empowerment. Qualitative methodologies emerged as the dominant approach in this research landscape, with a particular focus on countries boasting high gender equality. Furthermore, industries that predominantly target women in their advertising campaigns, such as fashion, luxury apparel, beauty, and personal care, occupy a central position in the existing body of literature. These findings encourage scholars to embark on future research aligned with the proposed research trends, particularly in regions characterized by lower gender equality and within gender‐neutral or male‐dominated industries.
Respiratory viral detection in the plasma and cerebrospinal fluid (CSF) of young febrile infants
Authors: Nicholson Erin G. , Avadhanula Vasanthi , Sahni Leila C. , Ferlic‐Stark Laura , Maurer Lauren , Boom Julie A. , Piedra Pedro A. 
Published: February 2024

AbstractBackgroundRespiratory viral infections are common in febrile infants ≤90 days. However, the detection of viruses other than enterovirus in the blood and cerebrospinal fluid (CSF) of young infants is not well defined. We sought to quantify the occurrence of respiratory viruses in the blood and CSF of febrile infants ≤90 days.MethodsWe conducted a nested cohort study examining plasma and CSF samples from febrile infants 15–90 days via rtPCR. The samples were tested for respiratory viruses (respiratory syncytial virus, influenza, enterovirus, parechovirus, adenovirus, bocavirus). Clinical and laboratory data were also collected to determine the presence of serious bacterial infections (SBI).ResultsTwenty‐four percent (30 of 126) of infants had plasma/CSF specimens positive for a respiratory virus. Enterovirus and parechovirus were the most commonly detected respiratory viruses. Viral positivity was highest in plasma samples at 25% (27 of 107) compared with CSF samples at 15% (nine of 62). SBIs (specifically urinary tract infections) were less common in infants with a sample positive for a respiratory virus compared to those without a virus detected (3% vs. 26%, p = 0.008).ConclusionsOur findings support the use of molecular diagnostics to include the identification of parechovirus in addition to enterovirus in febrile infants ≤90 days. Additionally, these data support the utilization of blood specimens to diagnose enterovirus and parechovirus infections in febrile infants ≤90 days.
The comparison of fluidized positioners and traditional gel pads for skin protection in neurosurgical patients undergoing lateral and prone positions: A retrospective analysis with propensity score matching method
Authors: Zeng Shuyan , Tian Ziyang , Gong Fengqiu , Wang Fujuan , Xie Manying , Chen XiaoJun , Liao ShuFeng 
Published: February 2024

AbstractTo compare fluidized positioners and gel pads for skin protection in neurosurgery patients placed in lateral and prone positions. It is one of the major challenges that operating room nurses face in protecting the skin during the long duration of neurosurgery. Currently, there are increasing tools available to protect the skin under pressure, and various tools practice well in the clinic. Fluidized positioners are newly emerging protective pads that have been clinically effective in protecting the skin, but no studies have compared them to previous pads. This is a retrospective cohort study. Data from 706 patients who underwent neurosurgery between January 2018 and December 2021 were systemically reviewed. Patients undergoing long‐term neurosurgery in the neurosurgical lateral and prone positions were divided into two groups: fluidized positioners or gel pads. Propensity score matching (PSM) was performed for group balance (1:1 ratio) using the following baseline characteristics: age, gender, ASA (American Society of Anesthesiologists) classification, duration of surgery, surgical position and underlying disease. The incidence of decubitus, and length of stay (LOS) in the hospital were compared between the two groups. The results were obtained for 394 patients in the fluidized positioner group with a 3.8% incidence of pressure ulcers and 312 patients in the gel pad group with an 8% incidence of pressure ulcers, which were unbalanced in terms of gender, ASA, hypertension and diabetes data. After a PSM, patients were compared in terms of pressure ulcer incidence (3.7% vs. 7.8%, p = 0.034) and LOS (22.35 vs. 25.65 days, p < 0.001). Fluidized positioners can effectively reduce the incidence of pressure injury in lateral and prone positions of neurosurgery. The results of this study may contribute to the development of policies to prevent the development of pressure ulcers during neurosurgical procedures.
Exploration of machine learning models for surgical incision healing assessment based on thermal imaging: A feasibility study
Authors: Li Fanfan , Zhang Hongyu , Xu Shangqing , Ma Xiaoli , Luo Na , Yu Youzhen , He Wenhui , Jin Hongying , Wang Min , Wang Ting , Wang Xiaolan , Zhang Yimei , Ma Guojing , Zhao Dan , Yue Qin , Wang Panpan , Ma Minjie 
Published: February 2024

AbstractIn this study, we explored the use of thermal imaging technology combined with computer vision techniques for assessing surgical incision healing. We processed 1189 thermal images, annotated by experts to define incision boundaries and healing statuses. Using these images, we developed a machine learning model based on YOLOV8, which automates the recognition of incision areas, lesion segmentation and healing classification. The dataset was divided into training, testing and validation sets in a 7:2:1 ratio. Our results show high accuracy rates in incision location recognition, lesion segmentation and healing classification, indicating the model's effectiveness as a precise and automated diagnostic tool for surgical incision healing assessment. Conclusively, our thermal image‐based machine learning model demonstrates excellent performance in wound assessment, paving the way for its clinical application in intelligent and standardized wound management.
Impact of evidence‐based nursing on surgical site wound infection after caesarean: A meta‐analysis
Authors: Zhang Li‐Hua , Wu Jian‐Li , Zhang Qin , Li Nai‐Mei , Li Wen‐Ying 
Published: February 2024

AbstractWe conducted this study to investigate the effect of evidence‐based care on surgical site wound infection after caesarean section. A computerised search of PubMed, Embase, Google Scholar, Cochrane Library, China National Knowledge Infrastructure and Wanfang databases for randomised controlled trials (RCTs) on the use of evidence‐based care in caesarean section delivery was applied from the database inception to November 2023. Two researchers independently screened the literature, extracted data and performed quality assessment based on inclusion and exclusion criteria. Stata 17.0 software was applied for data analysis. Twenty‐one RCTs involving 3269 caesarean sections were finally included. The analysis revealed the implementation of evidence‐based nursing interventions was effective in reducing the incidence of post‐caesarean section wound infections (OR = 0.29, 95% CI: 0.21–0.39, p < 0.001) and complications (OR = 0.29, 95% CI: 0.23–0.38, p < 0.001) compared with conventional care. This study shows that the application of evidence‐based nursing in postoperative caesarean section care can effectively reduce the incidence of postoperative wound infection and complications and improve the quality of life, which is worthy of clinical nursing application and promotion.
RETRACTED: Effects of negative‐pressure wound therapy in the prevention of surgical‐site wound infection after vascular surgery: A meta‐analysis
Authors: Yu Xiang , Xie Ping , Li Jin‐Ze , Cao Lei , Ye Jin 
Published: February 2024

AbstractThis meta‐analysis systematically evaluates the impact of negative‐pressure wound therapy (NPWT) on surgical‐site wound infection after vascular surgery. A comprehensive computerized search was conducted, from database inception to November 2023, in PubMed, Embase, Google Scholar, Cochrane Library, China National Knowledge Infrastructure, and Wanfang databases for randomized controlled trials (RCTs) on the application of NPWT in vascular surgery. Two researchers independently screened the literature, extracted data, and conducted quality assessments based on inclusion and exclusion criteria. Data analysis was performed using RevMan 5.4 software. A total of 11 RCTs involving 1597 vascular surgery patients were included. The analysis revealed that the application of NPWT in vascular surgery significantly reduced the incidence of wound infections (OR = 0.43, 95% CI: 0.32–0.58, p < 0.001) and complications (OR = 0.40, 95% CI: 0.27–0.58, p < 0.001). Additionally, NPWT was found to decrease the occurrence of both superficial wound infections (OR = 0.63, 95% CI: 0.36–1.12, p = 0.12) and deep wound infections (OR = 0.47, 95% CI: 0.19–1.16, p = 0.10), although these differences were not statistically significant. This study indicates that NPWT, compared with conventional treatment methods, has significant advantages in preventing postoperative wound infections and complications in vascular surgery patients and is therefore worthy of widespread clinical adoption.
Analysis of surgical site infection and tumour‐specific survival rate in patients with renal cell carcinoma after laparoscopic radical nephrectomy
Authors: Meng Shuai , Meng Meng , Wang Shouwu , Zheng Wei 
Published: February 2024

AbstractSurgical site infections (SSIs) may pose a significant risk to patients undergoing surgery. This study aims to explore the risk factors for SSIs in patients undergoing laparoscopic radical nephrectomy for renal cell carcinoma and the impact of infection on tumour‐specific survival (CSS) after nephrectomy for renal cell carcinoma. To explore the risk factors for SSIs in patients undergoing laparoscopic radical nephrectomy for renal cell carcinoma and the impact of infection on tumour‐specific survival (CSS) after nephrectomy for renal cell carcinoma. A retrospective analysis was conducted on 400 patients in our hospital from June 2021 to June 2023. This study divided patients into two groups: those with SSI and those without SSI. Collect general data and information related to the operating room. Clearly defined inclusion and exclusion criteria. Select surgical time, laminar mobile operating room use, and intraoperative hypothermia as observation indicators. Perform statistical analysis using SPSS 25.0 software, including univariate, multivariate, and survival analyses of wound‐infected and uninfected patients. Out of 400 patients, 328 had no SSIs, 166 died during follow‐up, 72 had SSIs, and 30 died during follow‐up. There was no statistically significant difference (p > 0.05) in comparing primary data between individuals without SSIs and those with SSIs. There were statistically significant differences (p < 0.05) in surgical time, nonlaminar flow operating room use, and intraoperative hypothermia. The postoperative survival time of SSI patients with a tumour diameter of 7.0–9.9 cm was significantly longer than that of SSI patients, and the difference was statistically significant (p < 0.05). The occurrence of severe infection in patients with other tumour diameters did not affect postoperative survival, and the difference was not statistically significant (p > 0.05). After multiple factor analysis, it was found that severe infection can prolong the postoperative survival of patients with tumour diameter exceeding 7 cm (HR = 0.749, p < 0.05). This study identified nonlaminar flow operating rooms, prolonged surgical time, and intraoperative hypothermia as significant risk factors for SSIs. After nephrectomy for renal cell carcinoma patients with a tumour diameter of 7–9.9 μ m, perioperative infection can prolong their survival. However, it has no significant effect on patients with other tumour diameters.
Assessing biomarkers for post‐surgical wound healing: A meta‐analysis of exosome‐based CircRNA in breast cancer recovery
Authors: Zhang Yunsuo , Tao Kai , Ding Lachun , Zhao Yi 
Published: February 2024

AbstractTo evaluate the diagnostic potential of exosome‐based circular RNAs (circRNAs) as biomarkers for wound healing in patients after breast cancer surgery, we conducted a comprehensive meta‐analysis of studies that measured exosome‐based circRNA levels in breast cancer patients post‐surgery. Data sources included several biomedical databases up to April 2023. Two independent reviewers extracted the data and assessed study quality. Sensitivity, specificity and diagnostic odds ratios were synthesized using random‐effects model with subgroup analyses performed based on study characteristics. Seventeen studies met the inclusion criteria, encompassing a total of 1234 patients. The pooled sensitivity and specificity of exosome‐based circRNA for detecting wound healing complications were 0.85 (95% CI: 0.77–0.91) and 0.83 (95% CI: 0.78–0.88), respectively. The area under the summary receiver operating characteristic (SROC) curve was 0.90, indicating high diagnostic accuracy. Subgroup analyses revealed that diagnostic performance was consistent across studies of different geographic regions and sample types but indicated potential variability related to patient age and study design. Exosome‐based circRNA profiles exhibited the high diagnostic accuracy for monitoring wound healing in breast cancer post‐operative care. These findings supported the potential utility of circRNA as non‐invasive biomarkers for post‐surgical recovery. However, variability among studies suggested the need for standardized protocols in biomarker measurement. Future research should focus on longitudinal studies to validate the prognostic value of these biomarkers and investigate their role in personalized patient management.
Whether a religious group membership is shared and salient influences perceived similarity, political support, and helping intention toward refugees, but not charitable donation
Authors: Albayrak‐Aydemir Nihan , Gleibs Ilka Helene 
Published: February 2024

AbstractThis research investigates the ways in which (un)shared religious group memberships contribute to individual helping responses through perceived similarity in the context of a refugee emergency. Across three studies (N = 762), we examined religious sub‐groups of British people's helping responses to religious subgroups of Syrian refugees, in quasi‐experimental and experimental designs. Overall findings suggest that sharing a religious group membership with refugee targets increases perceived similarity, political support, and helping intention, but not charitable donation—regardless of shared group membership being subtle or salient. However, when refugee targets' religious identity is that of a salient unshared group membership, not sharing a religious group membership reduces perceived similarity, political support, and helping intention, among those who are religious—with again charitable donation remaining unchanged. These results provide critical insights into developing more effective and unique strategies to promote and mobilize support for refugees among different groups of potential helpers.