bluuebunny/crossref_metadata_2025_split huggingface dataset:
Salivary cardiac-enriched FHL2-interacting protein is associated with higher diastolic-to-systolic-blood pressure ratio, sedentary time and center of pressure displacement in healthy 7-9 years old school-children
Authors: Vasileva Fidanka , Font-Lladó Raquel , Carreras-Badosa Gemma , Roman-Viñas Blanca , Cadellans-Arróniz Aïda , López-Bermejo Abel , Prats-Puig Anna 
Published: January 2024

IntroductionCardiac-enriched FHL2-interacting protein (CEFIP) is a recently identified protein, first found in the z-disc of striated muscles, and related to cardiovascular diseases. Our objectives are: 1) to quantify CEFIP in saliva in healthy 7-9 years old school-children; and 2) to assess the associations of salivary CEFIP concentration and blood pressure, physical (in)activity and physical fitness in these children.MethodsA total of 72 children (7.6 ± 0.3 years) were included in the study, recruited in primary schools in Girona (Spain). A sandwich enzyme-linked immunosorbent assay was used (abx506878; Abbexa, United Kingdom) to quantify CEFIP in saliva. Anthropometric evaluation was performed [body mass, height and body mass index (BMI)]. Systolic and diastolic blood pressure were measured by means of an electronic oscillometer and the diastolic-to-systolic blood pressure ratio (D/S BP ratio) was calculated. Physical (in)activity [sedentary time and time spent in physical activity (PA)] were assessed by means of a triaxial Actigraph GT3X accelerometer (Actigraph, Pensacola, FL, USA) that children were instructed to wear for 24h during 7 conssecutive days. Finally, physical fitness (speed and agility, explosive power of legs, handgrip strength, flexibility and balance) were assessed through validated and standardized testing batteries.ResultsCEFIP was easily detected and measured in all saliva samples (mean concentration: 0.6 ± 0.2 pg/ml). Salivary CEFIP was positively associated with D/S BP ratio (r=0.305, p=0.010) and sedentary time (r=0.317, p=0.012), but negatively associated with PA in 7-9 years old school-children (r=-0.350, p=0.002). Furthermore, salivary CEFIP was related to lower level of balance i.e., higher center of pressure (CoP) displacement in these children (r=0.411, p&lt;0.001). The associations of salivary CEFIP with D/S BP ratio (Beta=0.349, p=0.004), sedentary time (Beta=0.354, p=0.009) and CoP displacement (Beta=0.401, p=0.001), were maintained significant after adjustment for potential confounding variables such as age, gender and BMI in linear regression analyses.ConclusionCEFIP can be easily assessed in saliva as a promising biomarker associated with cardiovascular health in 7-9 years old school-children. Interestingly, higher salivary CEFIP concentration was related to higher D/S BP ratio, more sedentary time and higher CoP displacement i.e., lower level of balance in these children.
Biochar addition to compost heat recovery systems improves heat conversion yields
Authors: Pivato Alberto , Malesani Rachele , Bocchi Stefano , Rafieenia Razieh , Schievano Andrea 
Published: January 2024

Introduction: Compost heat recovery systems (CHRS) represent an emerging technology to recover residual woody biomass from agroforestry and forestry activities and use the heat that is naturally produced during aerobic biodegradation (composting). However, a low oxygen concentration in the gas phase and self-drying and compaction of the compost body often limit efficient oxidation by microbial communities. Woodchip-derived biochar has often been proposed as a bulking agent and improver of water retention and of oxygen accessibility in the composting process, but the literature reporting its effects in the CHRS is scarce.Methods: Here, biochar (average particle size of 10 mm) was added at 10% (on weight basis) to chipped pruning residues into two bench-scale-controlled reactors (0.2 m3), operated in parallel for 57 days.Results and Discussion: The addition of 10% (w/w) biochar to the composting body increased biodegradation yields by approximately 50% and improved oxidation rates over readily biodegradable organic fractions (addition of cheese whey). Temperatures were on average 1.34°C higher, and heat extraction flux was also improved in the presence of biochar (0.3 kW/m3) versus in its absence (0.1 kW/m3). The organic matter mass balance resulted in approximately 50% higher biodegradation yield and improved oxidation rates over readily biodegradable organic fractions. Microbial analysis highlighted a higher concentration of thermophilic species and a lower concentration of well-known pathogenic and antibiotic-resistant genera in the presence of biochar.
Thermal gradient strategy to improve seeding for high rate zero excess lithium metal batteries
Authors: Raj Abhi , Atkinson Robert W. , Kingston Todd A. , Carter Rachel , Love Corey T. 
Published: January 2024

Zero excess lithium metal batteries (LMBs) have traditionally suffered from short cycle life due to nonuniform processes that result in parasitic side reactions and a subsequent loss of lithium inventory and electrolyte. The experiments herein demonstrate that zero excess LMB cells cycled with a low thermal average and thermal gradient outperform cells cycled under isothermal conditions during early cycles. Specifically, a low thermal average of ∼6.4°C and thermal gradient of &lt;1°C across the cell is shown to increase the overpotential for lithium deposition at the anode current collector, likely resulting in smaller and higher density nucleates, providing film like morphologies observed with microscopy. Improved performance from this approach is demonstrated at high cycling rates (&gt;4C) and mismatched charge/discharge rates. Optimal cycling behavior was observed with 2C charging (30 min) and 3C discharging (20 min). These advantages were translated to the system relevant form factor-pouch cell (20X capacity). Based on the performance enhancement observed with extended application of a thermal gradient, we demonstrate the use of the environment as a formation strategy, to perpetuate improved plating in stripping over the cycle life of zero excess LMBs operating in ambient conditions.
Assessment of compression forces in a digitally modified short leg cast for pressure injury risk monitoring in healthy children
Authors: Vrankovic Matia Iva , Annaheim Simon , Willibald Jana , Lieber Jan , van Hedel Hubertus J. A. , Schlüer Anna-Barbara , Rossi René M. , Meyer-Heim Andreas 
Published: January 2024

IntroductionCasting is an essential treatment for neuro-orthopedic conditions in children with cognitive, sensory, and communicational disabilities. However, a main side-effect is the development of pressure injuries resulting in additional (wound) therapies and prolongation of the hospital stay. The primary aim of our study was to investigate the potential of objective pressure measurements in casts to assess the risk for pressure injury development.MethodsFive pediatric healthy participants were included in this study. We measured the global and the local compression force at body sites prone to pressure injury development for different body positions and the transfer in-between in a cast equipped with pressure sensors. These conditions resulted in partial or full body weight loading.Results and discussionThe global maximum compression force was affected significantly by body postures with partial and full loading of the cast and during transfer. The local compression force significantly correlated with the global compression force at the heel and instep area. In conclusion, the integration of sensing technologies into casts bears a high potential for early recognition of critical conditions inside the cast and inducing preventive measures in the at-risk population.
Unidirectional barbed sutures vs. interrupted intracorporeal knots in thoracoscopic repair of congenital diaphragmatic hernia in pediatrics
Authors: Shehata Mohamed Ali , Negm Mohamed Ahmed , Shalaby Mohamed Mahmoud , Mansour Mohamed Awad , Elhaddad Ahmed Abdelmhaimen 
Published: January 2024

BackgroundIntracorporeal suturing knots continue to be one of the most challenging and time-consuming steps in the thoracoscopic repair of congenital diaphragmatic hernia (CDH). Barbed unidirectional knotless sutures are designed to shorten surgical procedures by eliminating the need to tie knots. This work aimed to compare unidirectional barbed sutures and interrupted intracorporeal knots in the thoracoscopic repair of CDH in pediatrics regarding the time required to suture, operative time and complications.MethodsThis retrospective study included 139 patients presented with Bochdalek CDH. Patients were classified into early (neonatal) and late presentations. The hernia defect was repaired by unidirectional Barbed sutures (V-LocTM and StratafixTM sutures) in group B or by Conventional interrupted intracorporeal knots in group C.ResultsIn both early and delayed presentations, the time required to suture (15 and 13 min in group B, 33 and 28 min in group C for neonatal and delayed presentation respectively) was significantly shorter in group B. Complications (visceral perforation, wound infection, and recurrence) insignificantly differed between group B and group C of early presentation. No patients suffered from major complications in both groups.ConclusionsBoth unidirectional barbed sutures and intracorporeal knots were safe and effective. However, unidirectional barbed sutures are a time-saving choices for CDH thoracoscopic repair in early and late presentations.
Molecular and biochemical responses of sesame (Sesame indicum L.) to rhizobacteria inoculation under water deficit
Authors: dos Santos Anderson Reges , da Rocha Geisenilma Maria Gonçalves , Machado Alexandre Paulo , Fernandes-Junior Paulo Ivan , Arriel Nair Helena Castro , Gondim Tarcisio Marcos de Souza , de Lima Liziane Maria 
Published: January 2024

IntroductionWater scarcity is a challenge for sesame cultivation under rainfed conditions. In this scenario, a potential strategy to alleviate the water deficit is the application of plant growth-promoting bacteria. The objective of this study was to analyze the interaction of rhizobacteria with sesame cultivation under water deficit conditions.MethodsAn experiment was conducted in pots in a greenhouse using the BRS Morena sesame cultivar. The experimental design was completely randomized in a factorial scheme: 2 (irrigation regimes - daily irrigation and water deficit by suspending irrigation until 90% stomatal closure) x 6 (treatments with nitrogen or inoculants), with 5 replications. The types of fertilization were characterized by the addition of nitrogen (ammonium sulfate; 21% N), inoculants based on Bacillus spp. (pant001, ESA 13, and ESA 402), Agrobacterium sp. (ESA 441), and without nitrogen (control). On the fifth day after the suspension of irrigation, plant material was collected for gene expression analysis (DREB1 and HDZ7), activities of antioxidant enzymes (superoxide dismutase and catalase), relative proline content, and photosynthetic pigments. At the end of the crop cycle (about 85 days), production characteristics (root dry matter, aboveground dry matter, number of capsules, and thousand seed weight), as well as leaf nitrogen (N) and phosphorus (P) content, were evaluated.Results and DiscussionThere was a positive effect on both production and biochemical characteristics (proline, superoxide dismutase, catalase, and photosynthetic pigments). Regarding gene expression, most of the inoculated treatments exhibited increased expression of the DREB1 and HDZ7 genes. These biological indicators demonstrate the potential of rhizobacteria for application in sesame cultivation, providing nutritional supply and reducing the effects of water deficit.
Establishment of an experimental model of ovalbumin-induced atopic dermatitis in canines
Authors: Shin Ha-Young , Jin Hyung Jun , Tae Hyun-Jin , Oh Hong-Geun , Hwang Jeong Ho 
Published: January 2024

IntroductionA reliable standard model is required to evaluate the efficacy of new drugs for companion animals, especially dogs. Canine atopic dermatitis (cAD), also known as allergic inflammatory skin disease, is a common condition. Currently, the house dust mite animal model is used in the research of cAD; however, this model exhibits significant individual variation and is difficult to standardize. In this study, we used ovalbumin as an antigen to sensitize and stimulate dogs, thereby establishing a stable model mimicking the T-helper 2 (Th2) response seen in cAD. Our objective was to create a cAD model that could be employed to evaluate the efficacy of novel drugs and mimic the Th2 dominant allergic response observed in the pathogenesis of atopic dermatitis of dogs.MethodsIn this study, six beagles were used. Normal saline was applied to two animals, and ovalbumin to four, on their dorsal skin.ResultsThe ovalbumin-treated groups exhibited clinical cAD symptoms, such as pruritus and erythema. Moreover, plasma levels of the cAD markers immunoglobulin E and CCL17 chemokine were higher in the ovalbumin-treated group than in the vehicle control group. The skin thickness of the epidermis was significantly increased in the ovalbumin-treated group, with infiltration of inflammatory cells observed in the thickened dermis region. In conclusion, treatment of canine skin with an optimal concentration of ovalbumin induced typical cAD-like symptoms, and histological and molecular analyses confirmed an enhanced Th2-related immune response.ConclusionTherefore, we successfully established a suitable Th2-dominant response mimicking cAD, which will facilitate targeted research of atopic dermatitis in dogs.
Aspas de conotação autonímica: uma proposta sobre as heterogeneidades enunciativas do sujeito no discurso
Authors: De Macedo Ezequiel Bezerra Izaias 
Published: January 2024

Este artigo é sobre o fenômeno das heterogeneidades enunciativa do sujeiro no discurso. O trabalho se situa no campo da Linguística da Enunciação. Partimos da defesa de que a língua não deve ser vista somente como um sistema de combinação de signos, mas, sobretudo como linguagem engendrada por um sujeito. Em seguida, visitamos os principais postulados de Bakhtin e de Lacan, por meio dos quais buscamos uma articulação entre a linguística e a psicanálise, para chegarmos à teoria de Authier-Revuz sobre as heterogeneidades enunciativas do sujeito no discurso, as quais se apresentam de dois tipos: a heterogeneidade mostrada, que pode ser marcada ou não marcada e a heterogeneidade constitutiva. Investigamos excertos de enunciados que contêm aspas de conotação autonímica, tais como as aspas de diferenciação, de condescendência, de proteção, de questionamento ofensivo e de ênfase. Os resultados atestam que as aspas não se propõem ao dizer explícito. Cada discurso aparece dialeticamente como unitário, de um lado, e como plural, se considerarmos a outra face do mesmo, sendo isso que o faz heterogêneo. Nos termos que são aspeados, o sentido que as aspas produzem no enunciado do sujeito é guardado à distância. Nas considerações finais, podemos perceber que as aspas são uma espécie de sinal a ser decifrado no fio do discurso.
PENGARUH PENYULUHAN TERHADAP PENGETAHUAN TENTANG KARIES GIGI PADA KADER POSYANDU DI KECAMATAN SAKO KOTA PALEMBANG
Authors: Mujiyati Mujiyati 
Published: January 2024

Pos Pelayanan Terpadu (Posyandu) merupakan salah satu bentuk upaya yang dilaksanakan oleh, dari dan bersama masyarakat untuk memberdayakan dan memberikan kemudahan kepada masyarakat guna memperoleh pelayanan kesehatan bagi ibu dan anak balita. Kegiatan Posyandu merupakan upaya peningkatan kualitas sumber daya manusia sejak dini melalui layanan sosial dasar masyarakat untuk menunjang pembangunan. Kader merupakan faktor terbesar dan terpenting dari operasional Posyandu. Tujuan penelitian ini adalah diketahui pengetahuan tentang karies gigi pada kader Posyandu di Kecamatan Sako Kota Palembang melalui penyuluhan. Metode penelitian yang digunakan adalah penelitian eksperimental semu (quasi-experiment). Penelitian quasi-experiment merupakan salah satu bentuk penelitian eksperimen yang memanipulasi variable independen, pemilihan subjek penelitian ini dilakukan secara stratified random sampling. Sampel yang digunakan adalah Kader Posyandu di wilayah kerja Kecamatan Sako Palembang. Berdasarkan hasil uji paired t-test menggunakan program SPSS di peroleh P–value = 0,000, < 0,05 terdapat hubungan yang signifikan antara pengetahuan kader posyandu sebelum dan sesudah penyuluhan dengan metode ceramah. Kesimpulan yang didapat perubahan nilai rata-rata pengetahuan setelah dilakukan 3 kali pertemuan mengenai karies gigi sebelum dan sesudah penyuluhan.
Kata kunci : Posyandu, Penyuluhaan, Pengetahuan, Kader Posyandu
ANALISIS FAKTOR YANG MEMPENGARUHI INTEGRITAS LAPORAN KEUANGAN PERUSAHAAN PROPERTI, REAL ESTATE DAN KONSTRUKSI DI BEI
Authors: Pangestu Juan Carlos , Aprilliani Jessica , Rusli Yohanes Mardinata 
Published: January 2024

Integritas laporan keuangan menjadi hal penting untuk menjamin kehandalan informasi yang disajikan kepada investor. Penggunaan informasi dalam laporan keuangan merupakan hal yang penting bagi pihak internal maupun pihak eksternal dalam mengambil keputusan yang tepat sesuai kondisi perusahaan. Penelitian ini bertujuan untuk menguji pengaruh DebtToAsset, Rapat Komite audit, Kepemilikan Institusional, dan Jenis KAP terhadap Integritas Laporan keuangann pada perusahaan sektor Properti, Real Estate Dan Konstruksi yang terdaftar di Bursa Efek Indonesia tahun 2019-2021. Pengambilan sampel dilakukan dengan teknik purposive sampling. Jenis penelitian ini menggunakan uji statistik deskriptif dan metode regresi linear berganda. Objek dalam penelitian ini adalah Laporan keuangan Perusahaan Properti, Real Estate Dan Konstruksi yang listing di BEI dari periode 2019-2021. Hasil penelitian menunjukkan bahwa DebtToAsset memiliki pengaruh yang signifikan terhadap Integritas laporan keuangan sedangkan variabel lain tidak memiliki pengaruh
Analisis Dampak Firm Size, Leverage dan Profitabilitas Terhadap Environmental Disclosure
Authors: Saragih Fry Melda 
Published: January 2024

Penelitian ini bertujuan mengetahui bagaimana pengaruh firm size, leverage, dan profitabilitas terhadap environmental disclosure. Firm size, leverage, dan profitabilitas adalah variabel independen dalam penelitian ini, dan variabel dependen yaitu environmental disclosure. Dalam penelitian ini sebagai subjek adalah perusahaan manufaktur subsektor kimia yang terdaftar di Bursa Efek Indonesia dari 2017 hingga 2022. Sampel yang dikumpulkan dari studi ini dilakukan selama 6 tahun dengan 35 sampel dari 8 perusahaan. Metode yang digunakan adalag metode purposive sampling. Uji hipotesis penelitian menggunakan analisis regresi linier berganda dengan tingkat signifikansi 5% dan program SPSS 22. Hasil pengujian menunjukkan bahwa firm size tidak berdampak signifikan terhadap environmental disclosure dan leverage tidak berdampak signifikan pada environmental disclosure. Sedangkan profitabilitas berdampak signifikan negatif terhadap environmental disclosure. Penelitian yang telah dilakukan terbatas. Studi ini hanya memanfaatkan satu subsektor manufaktur, perusahaan manufaktur yang terdaftar dengan subsektor kimia. Tidak banyak pengamatan di Bursa Efek Indonesia, jadi pengungkapan lingkungan bisnis yang diamati tidak memberikan gambaran yang cukup tentang keadaan yang sebenarnya, hal tersebut terlihat dari hasil pengujian pada Adjusted R square yang disesuaikan yang menghasilkan hasil 78,3%, yang berarti bahwa variable independen lainnya tidak termasuk dalam penelitian ini, sehingga menghasilkan jumlah penelitian yang lebih besar.
Analisis Entrepreneurship Pondok Pesantren Entrepreneur Kanzun Najah Kota Batu (Studi Pendekatan Fenomenologi)
Authors: Raharto Eko , Abidin Munirul , Rofiq Aunur 
Published: January 2024

Kewirausahaan atau entrepreneursip telah banyak dilakukan oleh lembaga pendidikan formal hingga pondok pesantren. Banyak pesantren yang menjalankan program entrepreneur bagi para santrinya untuk membekali soft skill atau kemampuan berwirausaha setelah pulang kampung atau hidup bermasyarakat. Penelitian ini bertujuan untuk mengetahui perkembangan usaha para alumni setelah pulang kampung, apakah terjadi perkembangan atau justru berhenti, serta terbentuknya persepsi tentang kewirausahaan.Metode penelitian ini menggunakan kualitatif deskriptif dengan pendekatan fenomenologi, sedangkan informan penelitian sejumlah 4 orang alumni Pondok Pesantren Entrepreneur Kanzun Najah Kota Batu, dengan kriteria alumni yang sangat aktif berwirausaha ketika menjadi santri dengan pendapatan per bulan rata-rata Rp 2 juta atau lebih. Hasil penelitian menunjukan bahwa program atau kegiatan entrepreneur yang dilaksanakan di Pondok Pesantren Kanzun Najah Kota Batu telah membentuk karakteristik dan jiwa entrepreneur pada santrinya dan alumni. Para alumni yang telah pulang dan tinggal di kampung halamannya mengalami stagnanisasi atau bahkan berhentinya kegiatan usaha anggrek yang telah dijalankannya, sedangkan untuk alumni yang memilih tinggal di Kota Malang dan Kota Batu mengalami peningkatan yang positif dan signifikan pada perkembangan usahanya. Beberapa faktor yang menjadi penghambat antara lain: keterbatasan akses ekspedisi, jauh dari produsen anggrek yang berpusat di Kota Malang dan Batu, tidak ada tambahan motivasi atau penyemangat komunitas atau petani anggrek, dan keterbatasan pada sarana-prasana. Sedangkan dalam paradigm (cara pandang atau persepsi santri dan alumni pesantren Kanzun Najah telah tertanam dengan kuat bahwa, kekuatan pondasi atau kemandirian ekonomi merupakan keharusan bagi santri sebagai modal dalam berdakwah.
Pelatihan Manajemen Keuangan Usaha Kecil Dan Menengah Di Desa III Srinanti Kecamatan Banyuasin I Sumatera Selatan
Authors: Veronica Meilin 
Published: January 2024

Pengabdian kepada masyarakat dilakukan dalam bentuk pelatihan manajemen keuangan usaha kecil dan menengah di Desa III Srinanti Kecamatan Banyuasin I Sumatera Selatan. Manajemen keuangan adalah kegiatan yang meliputi perencanaan, pengelolaan, penyimpanan, hingga mengendalikan dana serta aset perusahaan. Pengelolaan keuangan harus dihandle dengan perencanaan yang matang agar tidak menimbulkan masalah di kemudian hari yang merugikan usaha. Dari hasil kegiatan pelatihan tersebut, dapat menambah pengetahuan peserta dalam pemahaman manajemen keuangan UKM serta meningkatkan kinerja keuangan Usaha Kecil dan Menengah (UKM). Pelatihan ini diberikan kepada pemilik usaha yang ada di Desa III Srinanti Banyuasin I Sumatera Selatan dan merupakan langkah tepat untuk memotivasi selera bisnis masyarakat.
Diseño y Evaluación de un Sistema Fotovoltaico Aislado para Iluminación en Vías Rurales y Carga de Vehículos Eléctricos Basado En Un Enfoque Multipropósito
Authors: Cuji Cristian , Villarreal Jonathan 
Published: January 2024

Se presentan los resultados de una propuesta de un sistema fotovoltaico de alta eficiencia con aplicaciones multipropósito, implementado a lo largo de una carretera. Este sistema está diseñado para abordar cuestiones relacionadas con la iluminación, las telecomunicaciones y la carga de vehículos eléctricos. La necesidad de un sistema aislado surge de los apagones repentinos en el país que afectan la seguridad vial y la confiabilidad, así como la falta de señal telefónica en algunas zonas.
En el ámbito de la iluminación, se realiza un análisis utilizando el software DiaLux para garantizar el cumplimiento de los estándares adecuados de iluminación para diferentes tipos de carreteras. Además, el sistema multipropósito incluye la carga de vehículos eléctricos, que se está volviendo cada vez más relevante debido al cambio hacia vehículos más ecológicos. La provisión de carga de vehículos eléctricos a lo largo de las carreteras resuelve el problema de la autonomía limitada de los vehículos eléctricos y promueve su uso confiable. La evaluación del recurso energético mediante el método Glover y McCulloch es fundamental para diseñar un sistema eficiente capaz de satisfacer diversas necesidades del usuario. Además, la reducción de las emisiones de dióxido de carbono es un aspecto importante, ya que los vehículos eléctricos pueden contribuir significativamente a la reducción de las emisiones de gases de efecto invernadero en comparación con los vehículos de combustibles fósiles