bluuebunny/crossref_metadata_2025_split huggingface dataset:
Life after digital displacement: analog entrepreneurship and the revitalization of legacy technologies
Authors: Roundy Philip T. , Bayer Mark A. 
Published: October 2023

Purpose
Research at the interface of marketing and entrepreneurship has emphasized digital entrepreneurship and how entrepreneurs pursue business opportunities centered on new technologies. However, a different type of entrepreneurship focused on opportunities involving consumers’ (re)adoption of displaced analog technologies when digital alternatives are dominant – analog entrepreneurship – is a trend and counter phenomenon to digital entrepreneurship that is receiving intense practitioner interest but limited scholarly attention. The purpose of this article is to present a theoretical framework that explains the role of analog entrepreneurship in technology revitalization.

Design/methodology/approach
In this conceptual paper, the authors use the microfoundations perspective to develop a multilevel theory of analog entrepreneurship. The authors define and delineate the “analog entrepreneurship” concept and formulate a midrange theory explaining how entrepreneurs influence the reemergence of analog technologies.

Findings
The theory’s main insight is that the renewal of analog technologies is not confined to consumers. Entrepreneurs are creating businesses that stimulate demand for analog technologies. As a result of entrepreneurs’ activities, legacy analog technologies do not fade into nonexistence in the face of rival digital technologies.

Originality/value
The theory of analog entrepreneurship contributes to research at the intersection of entrepreneurship and marketing by expanding its focus to consider the entrepreneurs who revitalize displaced analog technologies when digital alternatives are dominant. The authors provide insight into the potential trajectories of technologies after their initial displacement and the role entrepreneurs play in shaping the late stages of technology lifecycles. The theory draws attention to an underexplored phenomenon made increasingly prevalent by recent technological disruptions and suggests an agenda for studying how entrepreneurs renew analog technologies.
Strengthening customer loyalty through financial satisfaction in the banking industry
Authors: Tegambwage Amani Gration , Kasoga Pendo Shukrani 
Published: October 2023

Purpose
This study aims to investigate the effect of financial satisfaction (FS) on customer loyalty in the banking industry.

Design/methodology/approach
The study followed an explanatory research design using responses from 334 respondents from commercial banks in Tanzania. A stepwise regression analysis was used to validate the relevance of the study model.

Findings
The results indicate a positive and statistically significant association between customer loyalty and FS with levels of assets (β = 0.598, p < 0.001), savings (β = 0.186, p < 0.001) and debts (β = 0.065, p < 0.001). Of the three dimensions of FS, the level of assets had the strongest contribution to customer loyalty, followed by the level of savings and debts, in that order.

Research limitations/implications
The study used a model of FS that was linked to customer loyalty in the Tanzanian banking industry. It is recommended that the model be tested in other environments to increase the generalizability of the findings.

Practical implications
This study provides an alternative way for banks to strengthen customer loyalty by enhancing FS.

Originality/value
The FS model (Joo and Grable, 2004) and the social exchange theory (Blau, 1964) are used in this study to propose a model of customer loyalty in the banking industry. Customer loyalty and FS have not been connected in prior studies.
An empirical study on implementation of sustainable production practices in Indian manufacturing industry
Authors: Jha Neeraj Kumar , Jasti Naga Vamsi Krishna , Chaganti Phaneendra Kiran , Kota Srinivas , Nagpal Gaurav 
Published: October 2023

PurposeSustainable production (SP) is an efficient and influential approach of production for Indian manufacturing industries as it preserves the social, environmental and economic aspects of production activities altogether. The objective of this research work is to investigate the implementation status of SP practices in Indian manufacturing industries by utilizing empirical survey methodology.Design/methodology/approachA questionnaire survey methodology was adapted, and the questionnaire was prepared by intense literature survey along with by opinions from experts in the field of SP. This questionnaire was sent to 753 different organizations at different locations across India. This study collected responses from manufacturing industries as per 2021 directory of Confederation of Indian Industries for the duration of 7 week. Top level managers were the target respondents. The study propagated with 242 responses which were observed complete in all respects.FindingsThe study identified that though the majority of the organizations are claiming to follow SP practices since long time, they actually are lagging in proper understanding SP practices. Majority of them are implementing it in specific departments in their organization. They are coming across multiple barriers in the implementation of SP practices among which unrecognized financial benefits and lack of proper government policies are prime. The study suggests that the Indian organizations needs feasible framework with adaptable guidelines.Research limitations/implicationsThis work is centered towards manufacturing organizations and targets only the leading industrial sectors in India. Thus, the outcomes of this study may not be generalized for all the sectors of Indian industries. Additionally, it can also be assumed that higher number of responses would have contributed to more clear visualization of implementation status of SP practices among Indian industries.Originality/valueSustainable approaches in production activities are very lucrative for industries worldwide, due to their advantages. Numerous researchers are also putting their efforts to explore more about various aspects of sustainability. Mostly they are focusing on single or few aspects of SP and its implementation in particular region or country. Very few research works are dedicated to knowing the implementation status of SP in Indian manufacturing industries and they are limited in various aspects. This study presents a dedicated approach to investigate the implementation status of SP practices in Indian manufacturing industries.
A minimalist approach for improved time imaging of a noisy vibroseis data: A case study from Jaisalmer Basin, Rajasthan
Authors: Das Subhra Pratim , Mukhopadhyay Sagarika , Kumar Anil , Jain Mamta , Singh Ranbir 
Published: October 2023

AbstractProcessing land seismic data, especially vibroseis data, is often challenging due to complicated near‐surface situations and source‐generated noise. The case study deals with noisy vibroseis data acquired in the Jaisalmer Basin. The near‐surface estimation in this area is difficult due to a possible velocity reversal manifested in the shingled patterns of the first breaks. The near‐surface workflow incorporates a model‐adaptive first break‐picking approach, essentially integrating two problems of first‐break‐picking and model estimation into a single problem. The signal‐conditioning workflow is based on cascaded scaling and single‐channel‐based noise reduction to prevent the removal of weak signals. Horizon‐based migration velocity analysis was used to focus reflectors on the constant velocity‐migrated stacks. This was particularly useful in areas with dubious velocity trends based on semblance panels. The velocity volume has structural consistency, which provides a better time‐migrated image. The workflow also incorporates a targeted post‐stack processing sequence to enhance continuity, sharpen discontinuities and improve the resolution, as notable by comparing the legacy‐processing results of the same dataset.
Attitudes to Pregnancy, Childbirth and Postnatal Complications in Medieval English Miracula
Authors: Nilson Ben , Frost Ruth 
Published: October 2023

AbstractThis article re‐examines the evidence about childbirth and related topics in the posthumous miracle collections of English saints. It finds forty‐eight such miracles in collections of thirteen English saints, mostly from the century or so after 1170. The article argues that the context in which the stories were composed is vitally important to understanding how they can be used. Contemporary concerns with miracles that could be verified constrained what stories the hagiographers could use. The nature of pregnancy and birth also limited what information could come to the keepers at the shrine in charge of collecting such stories. However, the writers were not acting as an elite vetting the information, but rather cooperated with their informants and had a sympathetic and positive view of the pregnant women. The miracula reveal that, unfazed by even gruesome gynaecological issues, the male hagiographers showed some knowledge about the birthing process. By examining the body of stories, we show what the miracula can and cannot tell us about pregnancy and childbirth.
Stories and Histories: Gendered Performances, Caste and Sociability in some Punjabi Domestic Tales
Authors: Malhotra Anshu 
Published: October 2023

AbstractThe article traces the performative, familial, women‐centric, intergenerational storytelling tradition through studying Punjabi domestic tales collected in a private, intimate archive, in an ambience of mourning and celebration. Deploying the ‘archival turn’ in history‐writing, the author argues to include personal archive as a valid source in disciplinary history. Using the idea of ‘genders as genres’, the article argues that in female‐centred folktales, told to women and children, women assert their point of view, speak of their needs and desires, and hold their own. Though they may not dismantle caste‐specific patriarchies, patriarchies in folktales are also unable to subdue women.
BITS: A Bayesian Isotope Turnover and Sampling model for strontium isotopes in proboscideans and its potential utility in movement ecology
Authors: Yang Deming , Bowen Gabriel J. , Uno Kevin T. , Podkovyroff Katya , Carpenter Nancy A. , Fernandez Diego P. , Cerling Thure E. 
Published: October 2023

Abstract

Strontium isotope ratios (87Sr/86Sr) of incrementally grown tissues have been widely used to study movement ecology and migration of animals. However, the time scale of 87Sr/86Sr incorporation from the environment into tissue and how it may influence data interpretation are still poorly understood. Using the relocation of a zoo elephant (Loxodonta africana) named Misha, we characterise and model the 87Sr/86Sr turnover process using high‐resolution measurements of its tusk dentine. We seek to develop a framework that can improve quantitative interpretation of 87Sr/86Sr data in tissues.

The 87Sr/86Sr transition associated with the relocation is measured using laser ablation inductively coupled plasma mass spectrometry (LA‐ICP‐MS) on a prepared tusk slab. We develop a turnover model (BITS), with a rapidly exchanging central pool and a slowly exchanging peripheral pool, in a Bayesian statistical framework. The measured dentine data are first used to calibrate model parameters. The parameters are then used to estimate possible 87Sr/86Sr input time series from two datasets via model inversion: a fidelity test using Misha's dentine data and a case study using published dentine measurements from an Alaskan Woolly Mammoth (Mammuthus primigenius).

The LA‐ICP‐MS data are consistent with a two‐compartment turnover process with equivalent half‐lives of 41 days for the central pool and 170 days for the peripheral pool. The model inversion shows good fidelity when estimating the intake 87Sr/86Sr time series associated with Misha's relocation. In the case study, the model suggests an abrupt pattern of change in, and a much wider range of, intake 87Sr/86Sr values than expressed in the woolly mammoth dentine data themselves.

Our framework bridges the gap between environmental 87Sr/86Sr variation and data measured in tusk dentine or other incrementally grown tissues. It could be coupled with movement models and additional isotope tracers to study seasonal residency or the spatial and temporal patterns of movement/migration. The generic turnover processes can be adapted to other isotope systems, additional incremental tissues, or other organisms, thus expanding our modelling toolkit to investigate niche partitioning, life history traits and behavioural patterns in conservation biology, archaeology and paleoecology.
Early Administration of Steroids in the Ambulance Setting: An Observational Design Trial (EASI‐AS‐ODT)
Authors: Fishe Jennifer N. , Garvan Gerard , Bertrand Andrew , Burcham Shannon , Hendry Phyllis , Shah Manish , Kothari Kathryn , Ashby David W. , Ostermeyer Daniel , Riney Lauren , Semenova Olga , Abo Benjamin , Abes Benjamin , Shimko Nichole , Myers Emily , Frank Marshall , Turner Tim , Kemp Mac , Landry Kim , Roland Greg , Blake Kathryn V. 
Published: October 2023

AbstractBackgroundIn the emergency department (ED), prompt administration of systemic corticosteroids for pediatric asthma exacerbations decreases hospital admission rates. However, there is sparse evidence for whether earlier administration of systemic corticosteroids by emergency medical services (EMS) clinicians, prior to ED arrival, further improves pediatric asthma outcomes.MethodsEarly Administration of Steroids in the Ambulance Setting: An Observational Design Trial is a multicenter, observational, nonrandomized stepped‐wedge design study with seven participating EMS agencies who adopted an oral systemic corticosteroid (OCS) into their protocols for pediatric asthma treatment. Using univariate analyses and multivariable mixed‐effects models, we compared hospital admission rates for pediatric asthma patients ages 2–18 years before and after the introduction of a prehospital OCS and for those who did and did not receive a systemic corticosteroid from EMS.ResultsA total of 834 patients were included, 21% of whom received a systemic corticosteroid from EMS. EMS administration of systemic corticosteroids increased after the introduction of an OCS from 14.7% to 28.1% (p < 0.001). However, there was no significant difference between hospital admission rates and ED length of stay before and after the introduction of OCS or between patients who did and did not receive a systemic corticosteroid from EMS. Mixed‐effects models revealed that age 14–18 years (coefficient −0.83, p = 0.002), EMS administration of magnesium (coefficient 1.22, p = 0.04), and initial EMS respiratory severity score (coefficient 0.40, p < 0.001) were significantly associated with hospital admission.ConclusionsIn this multicenter study, the addition of an OCS into EMS agency protocols for pediatric asthma exacerbations significantly increased systemic corticosteroid administration but did not significantly decrease hospital admission rates. As overall EMS systemic corticosteroid administration rates were low, further work is required to understand optimal implementation of EMS protocol changes to better assess potential benefits to patients.
Improved intra‐atrial conduction delay after successful ablation for atrial fibrillation by scar homogenization in right atrium
Authors: Seo Jeongduk , Park Yae Min , Shin Yong Hoon , Jang Albert Youngwoo , Kang Woong Chol , Chung Wook‐Jin , Kim Young‐Hoon , Choi In Suck 
Published: October 2023

AbstractAtrial fibrosis in the right atrium (RA) presenting as a low‐voltage zone might be the mechanism of atrial fibrillation (AF) and intra‐atrial conduction delay. The impact of scar homogenization in RA on intra‐atrial conduction delay is unknown. We describe a patient with paroxysmal AF and significant intra‐atrial conduction delay with repetitive atrial flutter, triggered from the lateral free wall in the RA between the significant low‐voltage zone and slow conduction area after pulmonary vein isolation. Linear ablation along the trabeculated lateral free wall in the RA to homogenize the scar was successfully performed, and the intra‐atrial conduction delay improved ultimately.
Textbook outcomes for liver resection: can a medium sized centre have acceptable outcomes?
Authors: Mclauchlan Jared , de Burlet Kirsten , Nonis Maria , Hore Todd , Connor Saxon 
Published: October 2023

AbstractBackgroundTextbook outcome (TO) is an objective, composite measure of clinical outcomes in surgery. TO in liver surgery has been used in previous international studies to define and compare performance across centres. This study aimed to review TO rates following liver resection at a single institution. The secondary aim was to use a CuSum analysis to evaluate monitoring of performance quality over time for colorectal cancer liver metastases (CRCLM).MethodsAll patients undergoing liver resection for benign and malignant causes from Christchurch Hospital hepatobiliary unit between 2005 and 2022 were included. Textbook outcomes measures were the absence of; intraoperative incidents, Clavien‐Dindo >3 complication, 90 day re‐admission, 90 day mortality, R1 resection, and post‐operative bile leak/liver failure. Sequential CuSum analysis was performed to review achievement of TO in liver resections for colorectal cancer liver metastases (CRCLM).ResultsFour hundred and seventy‐eight patients were included in this study, 54 had resection for benign pathology, 290 for CRCLM and 134 for other malignancies. TO was achieved in 74% of cases overall, with rates for benign, CRCLM and other malignancy being 82%, 73% and 74% respectively (P = 0.405). CuSum analysis documented a deterioration in performance after patient 60, with return to baseline by end of study period.ConclusionsTO for liver resection in a medium sized centre in New Zealand are comparable to published rates. It is possible to use process control techniques like CuSum with the binary result of TO to monitor performance, providing opportunity for continuous improvement in surgical units.
Design of the phase 3 MAESTRO clinical program to evaluate resmetirom for the treatment of nonalcoholic steatohepatitis
Authors: Harrison Stephen A. , Ratziu Vlad , Anstee Quentin M. , Noureddin Mazen , Sanyal Arun J. , Schattenberg Jörn M. , Bedossa Pierre , Bashir Mustafa R. , Schneider David , Taub Rebecca , Bansal Meena , Kowdley Kris V. , Younossi Zobair M. , Loomba Rohit 
Published: October 2023

SummaryBackgroundNon‐alcoholic steatohepatitis (NASH) is a progressive form of non‐alcoholic fatty liver disease (NAFLD) associated with steatosis, hepatocellular injury, inflammation and fibrosis. In a Phase 2 trial in adults with NASH (NCT02912260), resmetirom, an orally administered, liver‐targeted thyroid hormone receptor‐β selective agonist, significantly reduced hepatic fat (via imaging) and resolved NASH without worsening fibrosis (via liver biopsy) in a significant number of patients compared with placebo.AimsTo present the design of the Phase 3 MAESTRO clinical programme evaluating resmetirom for treatment of NASH (MAESTRO‐NAFLD‐1 [NCT04197479], MAESTRO‐NAFLD‐OLE [NCT04951219], MAESTRO‐NASH [NCT03900429], MAESTRO‐NASH‐OUTCOMES [NCT05500222]).MethodsMAESTRO‐NASH is a pivotal serial biopsy trial in up to 2000 adults with biopsy‐confirmed at‐risk NASH. Patients are randomised to a once‐daily oral placebo, 80 mg resmetirom, or 100 mg resmetirom. Liver biopsies are conducted at screening, week 52 and month 54. MAESTRO‐NAFLD‐1 is a 52‐week safety trial in ~1400 adults with NAFLD/presumed NASH (based on non‐invasive testing); ~700 patients from MAESTRO‐NAFLD‐1 are enrolled in MAESTRO‐NAFLD‐OLE, a 52‐week active treatment extension to further evaluate safety. MAESTRO‐NASH‐OUTCOMES is enrolling 700 adults with well‐compensated NASH cirrhosis to evaluate the potential for resmetirom to slow progression to hepatic decompensation events. Non‐invasive tests (biomarkers, imaging) are assessed longitudinally throughout, in addition to validated patient‐reported outcomes.ConclusionThe MAESTRO clinical programme was designed in conjunction with regulatory authorities to support approval of resmetirom for treatment of NASH. The surrogate endpoints, based on week 52 liver biopsy, serum biomarkers and imaging, are confirmed by long‐term clinical liver‐related outcomes in MAESTRO‐NASH (month 54) and MAESTRO‐NASH‐OUTCOMES (time to event).
Impaired neural circuitry of hippocampus in Pax2 nervous system‐specific knockout mice leads to restricted repetitive behaviors
Authors: Wang Ying , Wang Yizhuo , Tang Jiaming , Li Rui , Jia Yanan , Yang Hua , Wei Hongen 
Published: October 2023

AbstractIntroductionRestricted repetitive behaviors (RRBs), which are associated with many different neurological and mental disorders, such as obsessive‐compulsive disorder (OCD) and autism, are patterns of behavior with little variation and little obvious function. Paired Box 2 (Pax2) is a transcription factor that is expressed in many systems, including the kidney and the central nervous system. The protein that is encoded by Pax2 has been implicated in the development of the nervous system and neurodevelopmental disorders. In our previous study, Pax2 heterozygous gene knockout mice (Pax2+/− mice) showed abnormally increased self‐grooming and impaired learning and memory abilities. However, it remains unclear which cell type is involved in this process. In this study, we deleted Pax2 only in the nervous system to determine the regulatory mechanism of Pax2 in RRBs.MethodsIn this study, Pax2 nervous system‐specific knockout mice (Nestin‐Pax2 mice) aged 6–8 weeks and Pax2 flox mice of the same age were recruited as the experimental group. Tamoxifen and vehicle were administered via intraperitoneal injection to induce Pax2 knockout after gene identification. Western blotting was used to detect Pax2 expression. After that, we assessed the general health of these two groups of mice. The self‐grooming test, marble burying test and T‐maze acquisition and reversal learning test were used to observe the lower‐order and higher‐order RRBs. The three‐chamber test, Y‐maze, and elevated plus‐maze were used to assess social ability, spatial memory ability, and anxiety. Neural circuitry tracing and transcriptome sequencing (RNA‐seq) were used to observe the abnormal neural circuitry, differentially expressed genes (DEGs) and signaling pathways affected by Pax2 gene knockout in the nervous system and the putative molecular mechanism.Results(1) The Nestin‐Pax2 mouse model was successfully constructed, and the Nestin‐Pax2 mice showed decreased expression of Pax2. (2) Nestin‐Pax2 mice showed increased self‐grooming behavior and impaired T‐maze reversal behavior compared with Pax2 flox mice. (3) An increased number of projection fibers can be found in the mPFC projecting to the CA1 and BLA, and a reduction in IGFBP2 can be found in the hippocampus of Nestin‐Pax2 mice.ConclusionThe results demonstrated that loss of Pax2 in the nervous system leads to restricted repetitive behaviors. The mechanism may be associated with impaired neural circuitry and a reduction in IGFBP2.