bluuebunny/crossref_metadata_2025_split huggingface dataset:
KEANEKARAGAMAN JENIS IKAN DEMERSAL YANG TERTANGKAP DENGAN BUBU DI PERAIRAN NEGERI WASSU KABUPATEN MALUKU TENGAH
Authors: Paillin Jacobus Bunga , Haruna Haruna , Tuhumury Julian 
Published: December 2023

Bubu adalah alat penangkap ikan yang bersifat pasif yang digunakan sebagai jebakan oleh nelayan dan dipasang secara tetap sehingga memudahkan ikan masuk dan sulit untuk ikan keluar. Penelitian ini bertujuan untuk mengetahui komposisi jenis ikan demersal, keanekaragaman jenis dan keseragaman jenis ikan demersal di perairan Negeri Wassu Kabupaten Maluku Tengah. Dari hasil penelitian ini secara keseluruhan ikan yang tertangkap sebanyak 24 jenis. Pada lokasi muka labuang tertangkap 18 jenis dan lokasi amalua tertangkap 19 jenis. Nilai keanekaragaman jenis “Shanon-Wiener” (H’) pada lokasi muka labuang sebesar 2,59, sedangkan pada lokasi amalua sebesar2,67. Nilai keseragaman (Evenness Indices) pada lokasi muka labuang sebesar 0,90 sedangkan pada lokasi amalua sebesar 0,91.
HASIL TANGKAPAN IKAN ARMADA PENGGUNA E-LOGBOOK YANG BEROPERASI DI PELABUHAN PERIKANAN NUSANTARA AMBON
Authors: Hintjah Indah Z. , Matrutty Delly D.P. , Paillin Jacobus B. , Sabandar Abraham M. O. 
Published: December 2023

Pelaporan data hasil tangkapan dan aktivitas armada penangkapan ikan melalui aplikasi e-loog book diwajibkan bagi setiap armada tangkap >5 GT sesuai Peraturan Menteri Kelautan dan Perikanan nomor 33 Tahun 2021. Akan tetapi banyak armada diduga belum menggunakan aplikasi e-log book dalam melaporkan aktivitasnya di laut. Tujuan penelitian ini adalah: mendeskripsikan jenis dan jumlah armada penangkapan ikan pengguna log book maupun e log book yang mendaratkan hasil tangkapannya di PPN Ambon dan membandingkan hasil tangkapan armada pengguna log book dan e-log book di PPN Ambon. Pengambilan data dilakukan dengan cara observasi dan wawancara. Data diperoleh dari nahkoda, nelayan dan petugas pencatat data di PPN Ambon. Data dianalisis secara deskriptif kualitatif dengan bantuan program exel. Hasil analisa menunjukkan bahwa dari 513 armada penangkapan ikan yang beroperasi di PPN Ambon, hanya 88 armada dengan kapasitas >5 GT yang melaporkan aktivitas penangkapan menggunakan logbook, yakni armada pancing tonda, purse seine, pole and line dan pancing ulur, dan 32 diantaranya melaporkan aktivitas penangkapannya melalui aplikasi e-logbook. Produksi yang dihasilkan dari armada pengguna e-log book lebih tinggi dibandingkan pencatatan/pelaporan melalui log book secara manual.
Pengenalan Alat Navigasi, Keselamatan dan Kesehatan pada Kapal Penangkap Ikan Enterprise di Perairan Selat Makassar
Authors: Tomasila Leopold A. , Tuhumena Lolita C. , Sinau Silvester , Pattinaja Yvonne I. , Umbekna Sara 
Published: December 2023

On voyage fishing vessel should be equipped with proper navigation equipment. Cadets who will be working onboard of a fishing vessel should understanding and aware of navigational equipment, safety equipment and healthy equipment. Because ,it could cause accident and awareness on navigational equipment. One of the ways for cadets to understand about navigation equipment are Maps, Campasses, Global Positioning System, Radia and Automatic Identification System. Each of these navigation equipment are hhaving their own function and operating system. So, it is a mandatory for every cadets to understand and aware in operating sthes navigation and know about safety equipment and healthy equipment on Enterprise fishing vessel .
Acute Effects of Hypothermia and Inhalant Anesthesia on Ultrasonic Vocalizations and Neuroendocrine Markers in Neonatal Rats
Authors: Lamont Katherine A , Boynton Marcella H , Hickman Debra L , Fletcher Craig A , Williams Morika D 
Published: December 2023

AbstractNeonatal rodents undergo anesthesia for numerous procedures and for euthanasia by anesthetic overdose. However, data regarding whether neonatal anesthesia is humane are limited. Hypothermia (cryoanesthesia) is the most commonly used anesthetic protocol for neonatal rats 10 d of age or younger. However, hypothermia has recently been restricted in several countries due to perceived painful effects, including pain on rewarming. Minimizing the potential pain and distress of neonates in research is imperative, although very challenging. Traditional validated and nonvalidated behavioral and physiologic outcome measures used for adult rats undergoing anesthesia are unsuitable for evaluating neonates. Therefore, we investigated the effects of several anesthetic methods on neonatal rats by using the innovative objective approaches of noninvasive ultrasonic vocalizations and more invasive neuroendocrine responses (i.e., serum corticosterone, norepinephrine, glucose). Our results show that hypothermia leads to heightened acute distress in neonatal rats as indicated by prolonged recovery times, increased duration of vocalizations, and elevated corticosterone levels, as compared with neonates undergoing inhalational anesthesia. We demonstrate that inhalational anesthesia is preferable to cryoanesthesia for neonatal rats, and researchers using hypothermia anesthesia should consider using inhalational anesthesia as an alternative method.
AFECTIVIDAD Y LIRISMO EN NOSILATIAJ, LA BELLEZA DE DANIELA SEGGIARO: UN ABORDAJE SOBRE LA REPRESENTACIÓN DEL PUEBLO WICHÍ
Authors: Aban Ana Gabriela 
Published: December 2023

Este trabajo versa sobre la representación del pueblo wichí en la película Nosilatiaj, la belleza (2012) de Daniela Seggiaro. En el marco de una propuesta fílmica que explora una dimensión lírica-afectiva, el objetivo es analizar esta dimensión como modo de aproximación al universo cultural y simbólico de la comunidad wichí a partir de los aportes de Didi-Huberman y de las especulaciones teóricas sobre el llamado “giro afectivo”. La problemática de la representación de los pueblos dialoga también con un enfoque decolonial y estudios subalternos. Se postula, así, un abordaje de Nosilatiaj… en tanto territorio de lo sensible en el que se articulan las intensidades de un tejido social complejo con la experiencia afectiva de la realizadora, a través de un montaje fílmico que privilegia lo sensorial y la belleza de un pueblo sometido a condiciones que dificultan su subsistencia. El filme ensaya formas cinematográficas que presentifican el universo simbólico de la comunidad wichí a partir del trabajo con el cuerpo singular de la protagonista y a través de una visualidad perceptiva que posibilita evocar los vínculos vitales con la cultura de origen.
PENGOLAHAN SAMPAH ORGANIK MELALUI TERNAK MAGGOT DAN MIKROORGANISME LOKAL (MOL) DI WONOCATUR BANGUNTAPAN BANTUL DIY
Authors: Saidi Didi , Widiarti Ika Wahyuning , Widodo R. Agus 
Published: December 2023

Sampah telah menjadi permasalahan nasional sehingga pengelolaannya perlu dilakukan secara komprehensif dan terpadu dari hulu ke hilir agar memberikan manfaat menguntungkan, sehat bagi masyarakat dan aman bagi lingkungan, serta dapat mengubah perilaku masyarakat. Dusun Wonocatur Desa Banguntapan Kapanewon Banguntapan Kabupaten Bantul Yogyakarta memiliki pasar tradisional yang menghasilkan limbah organik yang berlimpah. Permasalahan utama adalah tidak tersedianya fasilitas pengelolaan limbah pasar baik limbah organik maupun limbah anorganik. Tujuan dari kegiatan ini adalah untuk menerapkan bioteknologi budidaya Maggot dan membuat mikrooragnisme local (MOL) dari limbah organik sampah pasar. Metode yang digunakan dalam kegiatan ini adalah: Ceramah, diskusi, pelatihan, praktek dan pendampingan. Sampah organik berupa limbah sayur dan buah merupakan nutrisi bagi Maggot, Magot merupakan salah satu serangga potensial berupa Black Soldier Fly atau Lalat Tentara Hitam, Spesies ini diketahui tidak membawa dan atau menularkan penyakit seperti lalat rumah/lalat hijau. Maggot memiliki kelebihan untuk dimanfaatkan, diantaranya mampu menguraikan beragam sampah organik dan sangat baik sebagai pakan alternatif untuk ikan, unggas dll. Limbah organik sebagai bahan baku untuk membuat mikroorganisme lokal (MOL) karena memiliki kandungan unsur hara dan mikroorganisme pengurai sebagai pupuk hayati, pupuk organik cair yang bermanfaat bagi tanaman. Dari hasil kegiatan dapat disimpulkan, bahwa masyarakat sangat tertarik dengan budidaya maggot dan pupuk organik cair atau MOL.Luaran yang dihasilkan adalah: Bioteknologi budidaya Maggot dan Mikroorganisme Lokal (MOL), Produk turunan Maggot (telur, bibit, fress Maggot, pupa) yang memiliki nilai jual, pupuk padat kasgot, produk MOL atau pupuk organik cair yang berkualitas.
The Effects of Bovine Colostrum on the Stress-Hyperglycemia Ratio and the Triglyceride-Glucose Index in Exercise-Trained Healthy Subjects: A Double-Blind, Placebo-Controlled Clinical Study
Authors: Al-Nimer Marwan , Al-Basri Ahmed , Satmbekova Dinara , DatKhayev Ubaidilla 
Published: December 2023

Bovine colostrum (BC) is a natural substance that has been shown of benefits for exercising, and reducing the blood glucose levels in type 2 diabetes. Stress hyperglycemia is a brief rise in blood glucose levels caused by physiological stress. This placebo-controlled clinical study aimed to investigate the effects of BC on stress hyperglycemia and the triglyceride-glucose index in healthy subjects who trained in resistance exercise. This research was carried out at Al-Kut University College from April 30th to November 30th, 2022. Fifty healthy young men were randomly assigned: Group I (n = 24) received a placebo, whereas Group II (n = 26) received a 500mg single oral dosage of BC nutraceutical pill. During the treatment period, both groups of volunteers engaged in resistance exercise training. Body mass index (BMI), waist circumference (WC), stress glucose ratio (SGR), triglyceride-glucose index (TyGI), and rate pressure product (as a hemodynamic response) were all measured at the start and end of the eight-week study.‎ Stress blood glucose levels were considerably higher in Group II following resistance training (89.0±6.5 vs 102.1±11.5mg/dL, p<0.001), whereas stress HbA1c% did not alter (4.70±0.25 vs 4.66±0.29, p=0.608). Bovine colostrum significantly increases the SGR from 1.01±0.03 to 1.18±0.13, p<0.001. The TyGI at the stress glucose level was increased by 2.7%. We conclude that bovine colostrum significantly elevates the stress hyperglycemic ratio without inducing significant changes in the TyGI following exercise. This impact is accompanied by a stabilizing hemodynamic response.
Bilosomes as Soft Nanovesicular Carriers for Ropinirole Hydrochloride: Preparation and In- vitro Characterization
Authors: Ali Samer Khalid , Entidhar J. Al-Akkam  
Published: December 2023

Bilosomes are nanovesicular carriers that contain bile salts and non-ionic surfactants in a bilayer with cholesterol. These are more ultra-deformable, elastic, and flexible than other nanovesicular carrier.Ropinirole hydrochloride (RH) is a non-ergot dopamine D2-agonist. It is used to manage Parkinson's disease and to minimize "on-off" variations in levodopa responsiveness. The oral bioavailability is about 50% due to it being extensively metabolized in the liver, with an elimination half-life of about 6 h.The aim of this study was to enhance oral drug delivery and provide the sustained release of RH by preparing it as soft nanovesicular carriers (bilosomes).Eight formulas of RH bilosomes were prepared by a reverse-phase evaporation method using mixed surfactant (span®60: tween®60 at 1:2 ratio), cholesterol and sodium deoxycholate as bile salt.All formulas were evaluated for their drug content, entrapment efficiency, vesicle size, polydispersity index, zeta potential, drug release, transmission electron microscopy and fourier transform infrared spectroscopy.Results showed all prepared RH bilosomes were in nano-range with vesicle size ranging (from 124.40±10.60 to 294.60±11.50) nm, Zeta potential ranged (from -16.955±7.372 to -23.22±0.880) mV and with entrapment efficiency % ranged (from 57.30±6.48% to 77.77±3.78%).
The best formula F5 showed vesicle size (160.60±15.82) nm, Zeta potential (-20.75±0.930) mV, and entrapment efficiency %(77.77±3.78%) with 84.39% in-vitro release of RH after 24 h.It is concluded that bilosomes are good nanovesicular carriers for enhancing oral drug delivery and providing the sustained release of RH and all that may enhance oral bioavailability for RH.
Serum Soluble Angiotensin-Converting Enzyme-2 Level and Its Potential Association With The Renin-Angiotensin-Aldosterone System in Non-Hypertensive Iraqi COVID-19 Patients: An Observational Study
Authors: Turki Mohammed A. , A. Kasim Ali 
Published: December 2023

Background: The novel coronavirus disease (COVID-19) is caused by Severe acute respiratory syndrome coronavirus 2 (SARS-Cov2) which utilizes angiotensin converting enzyme2 (ACE2) to invade the host cells. This membrane-bound peptidase is widely distributed in the body; its activity antagonizes the renin-angiotensin-aldosterone system (RAAS). Once SARS-Cov2 enters the cell, it causes downregulation of ACE2, resulting in the unopposed activation of RAAS. The unregulated activity of the RAAS system can deteriorate the prognosis in COVID-19 patients. A soluble form of ACE2 (sACE2) was reported to have a role in the SARS-Cov2 invasion of the susceptible cells.
Aim of the study: This study aims to investigate the potential association of serum levels of sACE2 and RAAS components in severe COVID-19 patients compared to healthy individuals.
Methods: Eighty-five participants enrolled in the study were grouped into 45 non-hypertensive severe COVID-19 patients and 40 healthy individuals with comparable age and gender. Serum levels of sACE2, renin, angiotensin 2, and aldosterone by ELISA, and serum potassium level was measured by turbidimetric method.
Results: The results showed a significant difference in the serum levels of sACE2 (lower), renin, angiotensin 2, and aldosterone (higher) in COVID-19 patients compared to the control subjects (p-value <0.001; for all.
Conclusion: Non-hypertensive severe COVID-19 patients have lower sACE2 and higher RAAS peptide levels, and they can serve as diagnostic markers of severe COVID-19 patients.
Recommendations: we recommend a future study with a larger sample size that enrolls COVID-19 patients with different severity levels.
Keywords: Aldosterone, Angiotensin, COVID-19, Renin, Soluble angiotensin converting enzyme 2
O uso não descrito em bula (off label) de medicamentos anti-histamínicos na pediatria
Authors: Morgana Gomes Candido Agnes , Silva dos Santos Breno , Eugenio da Silva Jefferson , Galuppi Auletta Lucas , Meneses Delfino Suellen , Dos Santos Pereira Thaynara , Bertoluci Raquel , Giorgetti Leandro 
Published: December 2023

O pediatra necessita ter uma maior sensibilidade de uma visão integral da criança e do adolescente, dentro do contexto social em que estão inseridos, diante da segurança e eficácia dos medicamentos prescritos, as quais depende das concentrações do fármaco no organismo.
No que dizem respeito às formulações pediátricas, os principais fatores que desestimulam a indústria farmacêutica a desenvolver medicamentos para crianças, contemplam: o número pequeno de sujeitos disponíveis para participar destas pesquisas, os elevados custos marginais, o mercado reduzido e a complexidade ética desses estudos. Nesse sentido, médicos praticam o uso não descrito em bula (off label), o qual pode ser definido como o uso não aprovado de um medicamento pelo órgão sanitário local.
Devido ao seu efeito sedativo os anti-histamínicos H1 lideram as prescrições off-label na pediatria, os motivos para o seu uso são diversos, contudo podemos destacar: indução ao sono, tratamento de gripe e tosse, rinite, dermatite, asma, otite e urticária. Visto que muitos medicamentos utilizados no tratamento de doenças alérgicas não passaram por estudos para populações pediátricas, devido a certas barreiras éticas, a prescrição off-label destes produtos acaba sendo comum e geram uma preocupação a respeito de possíveis eventos adversos, mesmo com a crescente preocupação e esforços para melhorar os cuidados de saúde praticados em crianças, especificamente através da utilização de medicamentos seguros e efetivos.
Dessa forma, no período pós-comercialização de um produto farmacêutico, os profissionais farmacêuticos dentro da farmacovigilância, como papel de Detentoras de Registro de Medicamentos (DRM), monitoram informações de segurança e, a partir delas, realizam avaliações benefício-risco e estabelecem medidas de minimização de risco, além de ser um dever e compromisso ético do farmacêutico instruir os pais e responsáveis das crianças mesmo quando o uso dos medicamentos está fora dos rótulos.
Broken Heart Syndrome: A Rare Case of Recurrent Reverse Takotsubo Cardiomyopathy Associated with Acute Respiratory Failure: Reverse Takotsubo Cardiomyopathy
Authors: Pattanshetty Deepak , Jabeen Samina 
Published: December 2023

Background:
Takotsubo cardiomyopathy accounts for 1% of acute coronary syndrome presentations and has been increasingly recognized.1 Reverse Takotsubo cardiomyopathy, a variant form of Takotsubo cardiomyopathy has been described which presents with hyperdynamic function of the apical segments and hypokinesis of the basal or mid-ventricular segments, is the rarest type of acute stress cardiomyopathy, with mid-ventricular akinesia and preservation of apical and basal contractility.2
Case Report:
We report the rare case of an elderly lady admitted to our intensive care unit (ICU) with acute respiratory failure due to exacerbation of chronic obstructive lung disease and heart failure. Echocardiography revealed reverse Takotsubo cardiomyopathy. Cardiac catheterization showed nonobstructive coronary artery disease. The wall motion abnormalities resolved in 2 weeks. The case is unique in that she had an identical presentation one year earlier after she had entered the same dusty room!
Conclusion:
This case demonstrates that reverse Takotsubo cardiomyopathy with identical wall motion abnormalities can recur in a patient when re-exposed to similar stressful situation. Early recognition and appropriate management can prevent catastrophic outcomes.
Pediatric shunt failure: finding predictability in the sea of uncertainty
Authors: Nadeem Mohammed , Jirankali Vishal , Singha Souvik , Tyagi Gaurav , Uppar Alok Mohan , Beniwal Manish , Konar Subhas Kanti , Birua Gyani Jail Singh , Thyagatura Lingaraju , Shukla Dhaval , Srinivas Dwarakanath 
Published: December 2023

OBJECTIVE
Shunt malfunction is a complication that can have devastating implications. In this study, the authors aimed to evaluate the rate of shunt revision in a single institution over 5 years and to determine the factors associated with shunt revision in the pediatric population.

METHODS
This retrospective report assimilated data from all patients ≤ 18 years old who underwent shunt surgery between January 2015 and April 2021 at the authors’ institute with a minimum of 3 months of follow-up. Patient data regarding demographic characteristics, indications, clinical status, point of entry, operative and CSF findings, revision interval, and cause of failure were collected.

RESULTS
Between January 2015 and April 2021, 1112 pediatric patients underwent initial shunt surgery at the authors’ institute, among whom 934 patients met the inclusion criteria. Ninety-five patients underwent revision (shunt revision rate 10.2%). The cohort comprised 562 male and 368 female patients (no sex was recorded in 4 cases), with infratentorial tumors (37.8%) being the most common indication for the shunt. Multivariate analyses revealed that younger patient age, right-sided shunt, single surgeon, and shunt placement done in the evening and night were significantly associated with shunt failure. Among all the factors analyzed, female sex had the greatest risk of early shunt failure (OR 2.90 [95% CI 1.09–8.16], p = 0.037). The presence of prior external ventricular drainage was associated with an increased risk of multiple revisions (OR 6.67 [95% CI 1.60–32.52], p = 0.012). The most common cause of failure was obstruction, usually at the cranial end. The most common cause of distal failure was malposition of the abdominal end.

CONCLUSIONS
This study identifies various factors associated with shunt failure. Various goal-directed strategies toward modifiable risk factors can significantly improve shunt survival.
Subdural hematoma, retinal hemorrhage, and fracture triad as a clinical predictor for the diagnosis of child abuse
Authors: Mamaril-Davis James C. , Riordan Katherine , Sumdani Hasan , Bowlby Paul , Emami Neyestanak Maryam , Simpson Lauren , Avellino Anthony M. , Tang Andrew , Weinand Martin E. 
Published: December 2023

OBJECTIVE
Nonaccidental trauma (NAT) is a major cause of traumatic death during infancy and early childhood. Several findings are known to raise the index of clinical suspicion: subdural hematoma (SDH), retinal hemorrhage (RH), fracture, and external trauma. Combinations of certain injury types, determined via statistical frequency associations, may assist clinical diagnostic tools when child abuse is suspected. The present study sought to assess the statistical validity of the clinical triad (SDH + RH + fracture) in the diagnosis of child abuse and by extension pediatric NAT.

METHODS
A retrospective review of The University of Arizona Trauma Database was performed. All patients were evaluated for the presence or absence of the components of the clinical triad according to specific International Classification of Diseases (ICD)–10 codes. Injury type combinations included some variation of SDH, RH, all fractures, noncranial fracture, and cranial fracture. Each injury type was then correlated with the ICD-10 codes for child abuse or injury comment keywords. Statistical analysis via contingency tables was then conducted for test characteristics such as sensitivity, specificity, positive predictive value, and negative predictive value.

RESULTS
There were 3149 patients younger than 18 years of age included in the quantitative analysis, all of whom had at least one component of the clinical triad. From these, 372 patients (11.8%) had a diagnosis of child abuse. When compared to a single diagnosis of either SDH, RH, all fractures, noncranial fracture, or cranial fracture, the clinical triad had a significantly greater correlation with the diagnosis of child abuse (100% of cases) (p < 0.0001). The dyad of SDH + RH also had a significantly greater correlation with a child abuse diagnosis compared to single diagnoses (88.9%) (p < 0.0001). The clinical triad of SDH + RH + fracture had a sensitivity of 88.8% (95% CI 87.6%–89.9%), specificity of 100% (95% CI 83.9%–100%), and positive predictive value of 100% (95% CI 99.9%–100%). The dyad of SDH + RH had a sensitivity of 89.1% (95% CI 87.9%–90.1%), specificity of 88.9% (95% CI 74.7%–95.6%), and positive predictive value of 99.9% (95% CI 99.6%–100%). All patients with the clinical triad were younger than 3 years of age.

CONCLUSIONS
When SDH, RH, and fracture were present together, child abuse and by extension pediatric NAT were highly likely to have occurred.