bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wealth-based inequality in the continuum of maternal health service utilisation in 16 sub-Saharan African countries
Authors: Asefa Anteneh , Gebremedhin Samson , Marthias Tiara , Nababan Herfina , Christou Aliki , Semaan Aline , Banke-Thomas Aduragbemi , Tabana Hanani , Al-beity Fadhlun M. Alwy , Dossou Jean-Paul , Gutema Keneni , Delvaux Thérèse , Birabwa Catherine , Dennis Mardieh , Grovogui Fassou Mathias , McPake Barbara , Beňová Lenka 
Published: October 2023

Abstract
Background
Persistent inequalities in coverage of maternal health services in sub-Saharan Africa (SSA), a region home to two-thirds of global maternal deaths in 2017, poses a challenge for countries to achieve the Sustainable Development Goal (SDG) targets. This study assesses wealth-based inequalities in coverage of maternal continuum of care in 16 SSA countries with the objective of informing targeted policies to ensure maternal health equity in the region.

Methods
We conducted a secondary analysis of Demographic and Health Survey (DHS) data from 16 SSA countries (Angola, Benin, Burundi, Cameroon, Ethiopia, Gambia, Guinea, Liberia, Malawi, Mali, Nigeria, Sierra Leone, South Africa, Tanzania, Uganda, and Zambia). A total of 133,709 women aged 15-49 years who reported a live birth in the five years preceding the survey were included. We defined and measured completion of maternal continuum of care as having had at least one antenatal care (ANC) visit, birth in a health facility, and postnatal care (PNC) by a skilled provider within two days of birth. We used concentration index analysis to measure wealth-based inequality in maternal continuum of care and conducted decomposition analysis to estimate the contributions of sociodemographic and obstetric factors to the observed inequality.

Results
The percentage of women who had 1) at least one ANC visit was lowest in Ethiopia (62.3%) and highest in Burundi (99.2%), 2) birth in a health facility was less than 50% in Ethiopia and Nigeria, and 3) PNC within two days was less than 50% in eight countries (Angola, Burundi, Ethiopia, Gambia, Guinea, Malawi, Nigeria, and Tanzania). Completion of maternal continuum of care was highest in South Africa (81.4%) and below 50% in nine of the 16 countries (Angola, Burundi, Ethiopia, Guinea, Malawi, Mali, Nigeria, Tanzania, and Uganda), the lowest being in Ethiopia (12.5%). There was pro-rich wealth-based inequality in maternal continuum of care in all 16 countries, the lowest in South Africa and Liberia (concentration index = 0.04) and the highest in Nigeria (concentration index = 0.34). Our decomposition analysis showed that in 15 of the 16 countries, wealth index was the largest contributor to inequality in primary maternal continuum of care. In Malawi, geographical region was the largest contributor.

Conclusions
Addressing the coverage gap in maternal continuum of care in SSA using multidimensional and people-centred approaches remains a key strategy needed to realise the SDG3. The pro-rich wealth-based inequalities observed show that bespoke pro-poor or population-wide approaches are needed.
Hyperlipidemia in immune thrombocytopenia: a retrospective study
Authors: Han Shouqing , Lu Hui , Yu Yafei , Liu Xinguang , Jing Fangmiao , Wang Liang , Zhao Yajing , Hou Ming 
Published: October 2023

Abstract
Background
Immune thrombocytopenia (ITP) is an autoimmune hemorrhagic disease characterized by low platelet count and bleeding manifestations. However, some patients also suffered from atherosclerosis or even infarction. Apart from activated platelets, lipid metabolism takes a large part in the formation of atherosclerosis and metabolic syndrome. The lipid metabolic state in ITP patients is still unknown.

Methods
We retrospectively reviewed 302 hospitalized ITP patients in our cohort, comparing their blood lipids, bleeding symptoms, metabolic diseases and treatment responses.

Results
We found a high proportion of ITP patients suffered from hyperlipidemia, and other metabolic diseases including cardiovascular or cerebral atherosclerosis or infarction, hypertension, and type 2 diabetes. Hyperlipidemia was associated with severe bleeding and treatment refractoriness in ITP. Statins could alleviate thrombocytopenia and bleeding severity, and facilitate ITP treatment, while improving hyperlipidemia in ITP patients.

Conclusions
Our present study demonstrated that lipid metabolism might play an indispensable role in ITP pathogenesis and development.
Epstein-Barr virus infection: the micro and macro worlds
Authors: Huang Wei , Bai Lang , Tang Hong 
Published: October 2023

AbstractEpstein‒Barr virus (EBV) is a DNA virus that belongs to the human B lymphotropic herpesvirus family and is highly prevalent in the human population. Once infected, a host can experience latent infection because EBV evades the immune system, leading to hosts harboring the virus for their lifetime. EBV is associated with many diseases and causes significant challenges to human health. This review first offers a description of the natural history of EBV infection, clarifies the interaction between EBV and the immune system, and finally focuses on several major types of diseases caused by EBV infection.
The stress of nursing: exploring communicatively restricted organizational stress (CROS), effort-reward imbalance, and organizational support among a sample of U.S. working nurses
Authors: Boren Justin P. , Veksler Alice E. 
Published: October 2023

Abstract
Background
Nurses experience a constellation of negative outcomes such as lost productivity, based on their high levels of organizational stress. Following recommendations for best practices in health communication can dramatically improve the organizational climate for nurses and can have a significant effect on patient outcomes. In this study, we evaluate the impact of Communicative Restricted Organizational Stress (CROS) and effort-reward imbalance (ERI).

Methods
A mixed-methods approach was employed. A professional survey research vendor was contracted to obtain an appropriate national sample (N = 299) of working nurses in the United States of America. Participants completed an online closed-ended questionnaire for the quantitative portion of the study. Qualitative data were gathered from member-checking follow-up interviews.

Results
Results of the quantitative analysis indicated that nurses experience CROS, that these experiences are distressing, that CROS functions as an effort in the effort-reward-imbalance model, and that CROS and ERI contribute to negative outcomes such as insomnia, productivity lost, and poor general health. Specifically, a moderated moderation model accounted for 53% of the variance [F (7,290) = 47.363, p < .001] indicating that nurses with high levels of CROS distress and low levels of organizational support experienced the highest level of ERI in the presence of high nursing stress, t (296) = 3.05, p = .03, 95% CI [0.0038, 0.0178]. These findings were validated through member-checking qualitative interviews and specific overarching themes were explicated.

Conclusions
CROS is an important variable in understanding the experience of nursing stress. Furthermore, CROS serves as an effort in the ERI Model and serves to exacerbate nursing stress. We recommend practical implications for the improvement of psychosocial stress in an occupational environment for nurses.
Wide diagnostic and genotypic spectrum in patients with suspected mitochondrial disease
Authors: Grigalionienė Kristina , Burnytė Birutė , Ambrozaitytė Laima , Utkus Algirdas 
Published: October 2023

Abstract
Background
Mitochondrial Diseases (MDs) are a diverse group of neurometabolic disorders characterized by impaired mitochondrial oxidative phosphorylation and caused by pathogenic variants in more than 400 genes. The implementation of next-generation sequencing (NGS) technologies helps to increase the understanding of molecular basis and diagnostic yield of these conditions. The purpose of the study was to investigate diagnostic and genotypic spectrum in patients with suspected MD. The comprehensive analysis of mtDNA variants using Sanger sequencing was performed in the group of 83 unrelated individuals with clinically suspected mitochondrial disease. Additionally, targeted next generation sequencing or whole exome sequencing (WES) was performed for 30 patients of the study group.

Results
The overall diagnostic rate was 21.7% for the patients with suspected MD, increasing to 36.7% in the group of patients where NGS methods were applied. Mitochondrial disease was confirmed in 11 patients (13.3%), including few classical mitochondrial syndromes (MELAS, MERRF, Leigh and Kearns-Sayre syndrome) caused by pathogenic mtDNA variants (8.4%) and MDs caused by pathogenic variants in five nDNA genes. Other neuromuscular diseases caused by pathogenic variants in seven nDNA genes, were confirmed in seven patients (23.3%).

Conclusion
The wide spectrum of identified rare mitochondrial or neurodevelopmental diseases proves that MD suspected patients would mostly benefit from an extensive genetic profiling allowing rapid diagnostics and improving the care of these patients.
GenArk: towards a million UCSC genome browsers
Authors: Clawson Hiram , Lee Brian T. , Raney Brian J. , Barber Galt P. , Casper Jonathan , Diekhans Mark , Fischer Clay , Gonzalez Jairo Navarro , Hinrichs Angie S. , Lee Christopher M. , Nassar Luis R. , Perez Gerardo , Wick Brittney , Schmelter Daniel , Speir Matthew L. , Armstrong Joel , Zweig Ann S. , Kuhn Robert M. , Kirilenko Bogdan M. , Hiller Michael , Haussler David , Kent W. James , Haeussler Maximilian 
Published: October 2023

AbstractInteractive graphical genome browsers are essential tools in genomics, but they do not contain all the recent genome assemblies. We create Genome Archive (GenArk) collection of UCSC Genome Browsers from NCBI assemblies. Built on our established track hub system, this enables fast visualization of annotations. Assemblies come with gene models, repeat masks, BLAT, and in silico PCR. Users can add annotations via track hubs and custom tracks. We can bulk-import third-party resources, demonstrated with TOGA and Ensembl gene models for hundreds of assemblies.Three thousand two hundred sixty-nine GenArk assemblies are listed at https://hgdownload.soe.ucsc.edu/hubs/ and can be searched for on the Genome Browser gateway page.
MBE: model-based enrichment estimation and prediction for differential sequencing data
Authors: Busia Akosua , Listgarten Jennifer 
Published: October 2023

AbstractCharacterizing differences in sequences between two conditions, such as with and without drug exposure, using high-throughput sequencing data is a prevalent problem involving quantifying changes in sequence abundances, and predicting such differences for unobserved sequences. A key shortcoming of current approaches is their extremely limited ability to share information across related but non-identical reads. Consequently, they cannot use sequencing data effectively, nor be directly applied in many settings of interest. We introduce model-based enrichment (MBE) to overcome this shortcoming. We evaluate MBE using both simulated and real data. Overall, MBE improves accuracy compared to current differential analysis methods.
Increases in negative affective arousal precede lower self-esteem in patients with borderline personality disorder but not in patients with depressive disorders: an experience sampling approach
Authors: Heekerens Johannes Bodo , Schulze Lars , Enge Juliane , Renneberg Babette , Roepke Stefan 
Published: October 2023

AbstractBackgroundInstability in self-esteem and instability in affect are core features of borderline personality disorder (BPD). For decades, researchers and theorists have been interested in the temporal dynamics between these constructs. Some hypothesize that changes in affective states should precede changes in self-esteem (Linehan, Cognitive-behavioral treatment of borderline personality disorder. Diagnosis and treatment of mental disorders, 1993), while others suggest that changes in self-esteem should precede changes in affective states (Kernberg, Borderline conditions and pathological narcissism, 1975).MethodsIn this study, we investigated the temporal relations between negative affective arousal states and current self-esteem in daily life. Patients with BPD (n = 42) or depressive disorders (DD;n = 40), and non-clinical controls (NCC;n = 40) were assessed every 15 min for 13 h.ResultsAs expected, dynamic structural equation modeling showed higher levels of average daily negative affective arousal and lower levels of average daily self-esteem in the BPD group compared with the NCC group, and scores in the DD group were in-between the BPD and the NCC groups. In line with predictions based on Linehan’s (Cognitive-behavioral treatment of borderline personality disorder. Diagnosis and treatment of mental disorders, 1993) model of affective dysregulation in BPD, negative affective arousal (t) and subsequent self-esteem (t+ 1) were significantly linked only in the BPD group, implying that higher negative affective arousal is followed by lower current self-esteem in the next measurement (ca. 15 min later). Importantly, self-esteem (t) and subsequent negative affective arousal (t + 1) were not significantly related (Kernberg, Borderline conditions and pathological narcissism, 1975).ConclusionsOur findings suggest close dynamic temporal relations between affective instability and self-esteem instability in BPD, which highlights the importance of providing patients with means to effectively modulate high negative affective arousal states.
Comparison and simulation-based analysis of the sound field of Dong drum tower buildings
Authors: Mao Linqing , Ma Jianjun , Zhang Xin , Liu Bin , Niu Jianzhuang 
Published: October 2023

Abstract
Drum towers are the most prominent cultural markers and the major site for cultural ceremonies in Dong villages. The visibility and audibility of drum towers are important factors influencing the location and construction of buildings in Dong villages. In this paper, the authors map and classify 21 drum tower buildings according to three characteristics: shape of the plan, elevation of the enclosure, and aspect ratio of the longitudinal section. Having used the sound field simulation software Odeon to filter two of the three characteristics that were identical, the authors simulated drum towers with different values of the third characteristic to study the factors influencing their sound field. The correlation between the construction of the drum tower and its characteristics of sound was established, and the characteristics of the sound field as well as their adaptability were assessed by comparing different forms of drum towers. This can provide technical support for the protection and repair of drum towers, their renovation and upgrade, and the construction of new drum towers in the Dong region.
The impact of deproteinized bovine bone particle size on histological outcomes in sinus floor elevation: a systematic review and meta-analysis
Authors: Li Xin , Lin Shi-chen , Duan Shao-yu 
Published: October 2023

Abstract
Objectives
The main purpose of this study was to evaluate whether large granular bovine bone can be as effective as small granular bovine bone in maxillary sinus floor elevation.

Methods
A comprehensive online search of eligible articles was conducted using PubMed, EMBASE, Cochrane Library, Scopus, and Web of Science, and a systematic review and meta-analysis was performed from establishment to February, 2023. The outcome indicators were the percentage of connective tissue, the percentage of newly formed bone and the percentage of residual xenograft respectively. The meta-analysis was conducted by using the Stata 15.1 (Stata Conpernarn, USA) and Review Manager software5.4.1.

Results
After careful screening and review, a total of 4 studies were included for systematic review and meta-analysis. The data were extracted to compare the histological performance of bovine bones with different particle sizes after maxillary sinus elevation. No significant differences were found in the percentage of connective tissue, the percentage of newly formed bone, and the percentage of residual xenograft.

Conclusion
In this study, a systematically review of the previous literature showed that similar histological results were obtained for both large-particle bovine bone and small-particle bovine bone. Therefore, the large granular bovine bone and the small granular bovine bone were equally effective in maxillary sinus elevation. It is difficult to make conclusion from limited evidence from four studies. More clinical evidence was needed.
Assessment of hepatic fibrosis, portal hemodynamic changes, and disease severity in patients with HCV-related liver cirrhosis after sustained virologic response to direct-acting antiviral drugs (DAAs)
Authors: Hassan Waleed Attia , Kamel Sherif I. , Mahmoud Ibrahim Abdel Naby , Makhlouf Nahed , Moubark Mahmoud , Hassany Sahar M. 
Published: October 2023

Abstract
Background
Regression of fibrosis and improvement of portal hemodynamics after achievement of sustained viral response (SVR) in patients with chronic hepatitis C (HCV) is a subject of debate in different studies. Some studies reported improvement in the degree of fibrosis, while others did not find significant changes.

Objective
We aimed to evaluate changes in liver fibrosis, portal hemodynamics and clinical outcomes in patients with chronic HCV-related liver cirrhosis after the achievement of SVR with direct-acting antiviral drugs (DAAs).

Patients and methods
In our prospective longitudinal study, a total of 100 patients with chronic HCV infection-related liver cirrhosis were recruited, received DAAs, and completed the follow-up period. Clinical evaluation for assessment of liver disease severity using MELD and Child–Pugh class and scores were done. A noninvasive assessment of liver fibrosis using serum biomarkers (APRI index & FIB4 score) and share wave elastography (SWE) was done. Portal hemodynamic evaluation using Doppler ultrasound was done. All were done at baseline and 3 and 12 months after the end of therapy.

Results
A significant reduction in the degree of fibrosis was observed. Share wave elastography (SWE) readings showed 19.79% and 30.45% reduction 3 and 12 months after the end of therapy respectively (P < 0.001). Regarding the FIB4 score, the percentage of score reduction was 19.8% and 26.46% 3 and 12 months after the end of therapy, respectively (P < 0.01). APRI scores showed 22.6% and 41.09% reduction 3 and 12 months after the end of therapy respectively (P < 0.001). Significant improvement in Child–Pugh scores 3 and 12 months after the end of treatment was observed. Doppler ultrasound showed a significant increase in portal vein flow velocity, a significant decrease in time average mean velocity, and cross-section area 12 months after the end of treatment.

Conclusion
There was a considerable degree of reduction of liver fibrosis, improvement of portal hemodynamics, and Child–Pugh score in cirrhotic HCV patients who achieved SVR after DAAs.

Trial registration
ClinicalTrials.gov, ID: NCT03241823. Registered on 08 May 2017.
Evaluation of the prevalence of glucose-6-phosphate dehydrogenase deficiency in Al-Qassim region of Saudi Arabia
Authors: AlShomar Ahmad , Sula Idris , Al Abdulmonem Waleed , Saquib Nazmus 
Published: October 2023

Abstract
Background
Glucose-6-phosphate dehydrogenase (G6PD) deficiency, an X-linked disorder that is more common in males, is the most prevalent blood enzyme deficiency, affecting 5% of the population worldwide. Its prevalence in Saudi Arabia varies greatly from one region to another (4.7% to 12%), and no related data are available for the country’s Al-Qassim region.

Methods
This was a retrospective medical record-based study. Eligible patients were those who visited Dr. Sulaiman Al-Habib Hospital in Al-Qassim, Saudi Arabia, between June 2021 and November 2022, and underwent the test for G6PD enzyme deficiency. The study sample consisted of (n = 313) randomly selected Saudi patients. G6PD enzyme activity was evaluated using spectrophotometry.

Results
The prevalence of G6PD deficiency was 2.9%. The proportion of male patients (100%) was significantly higher than that of female patients. 88.9% of patients with G6PD deficiency experienced episodes of acute hemolysis and reported a history of favism, whereas 77.8% of the patients had a family history of favism.

Conclusion
The prevalence of G6PD deficiency was low in Al-Qassim region of Saudi Arabia.
Stochastic analysis of chemical reactions in multi-component interacting systems at criticality
Authors: Tiani Reda , Täuber Uwe C. 
Published: October 2023

Abstract
We numerically and analytically investigate the behavior of a non-equilibrium phase transition in the second Schlögl autocatalytic reaction scheme. Our model incorporates both an interaction-induced phase separation and a bifurcation in the reaction kinetics, with these critical lines coalescing at a bicritical point in the macroscopic limit. We construct a stochastic master equation for the reaction processes to account for the presence of mutual particle interactions in a thermodynamically consistent manner by imposing a generalized detailed balance condition, which leads to exponential corrections for the transition rates. In a non-spatially extended (zero-dimensional) setting, we treat the interactions in a mean-field approximation, and introduce a minimal model that encodes the physical behavior of the bicritical point and permits the exact evaluation of the anomalous scaling for the particle number fluctuations in the thermodynamic limit. We obtain that the system size scaling exponent for the particle number variance changes from

at the standard non-interacting bifurcation to

at the interacting bicritical point. The methodology developed here provides a generic route for the quantitative analysis of fluctuation effects in chemical reactions occurring in multi-component interacting systems.
Data Worlds: An Introduction
Authors: Bode Katherine , Goodlad Lauren M. E. 
Published: October 2023

Abstract
This introductory article calls attention to the shift from the “big data” discourse of the 2000s to the current focus on “AI” in its supposedly “responsible” and “human-centered” forms. Such rhetoric helps deflect attention from the profitable and surveillant accumulation of data and the worrisome concentration of power in a handful of companies. Alert to this problematic political economy, the issue's editors engage recent theories of data capitalism and argue that attention to processes of datafication helps to elude the pitfalls of data positivism, data universalism, and unintentional criti-hype. As the authors touch upon each contribution to this special issue, they call for critical AI studies to forge an interdisciplinary community of practice, alert to ontological commitments, design justice principles, and spaces of dissensus.