bluuebunny/crossref_metadata_2025_split huggingface dataset:
Healthcare Leadership Competence during Covid-19 Crisis in Tanjung Pinang, Riau Archipelago
Authors: Tubel Agusven  , Helen Tan Sui Hong  , Kamarudeen Babatunde Bello  
Published: October 2023

The study was conducted at the height of the pandemic when Indonesia was facing a steep rise of Covid-19 infections and the nation was grappling with various constraints. The key focus of this inquiry is to identify the major challenges faced by the health workers who provided health services, especially in Tanjung Pinang, the capital city of the Riau Archipelago province during such unprecedented health crisis. Data was collected via an online survey posing open-ended questions. Seventy-one healthcare personnel from the Riau Archipelago hospitals and healthcare institutions responded. The data was analysed using content analysis technique. The key findings revealed that the top three major challenges faced by the healthcare personnel, and the healthcare systems in general are citizen compliance to rules and procedures enforced to curb the spread of Covid-19, limited PPE and contagious disease medical supplies, and hospital readiness in treating patients related to COVID-19 infection. The findings also showed that healthcare leadership competence is very crucial when managing chaos during such healthcare crisis.
The Contribution of Fanaticism, Isthiqomah and Radicalism to Maslahah through the Management of Religious Conflict in the Riau Island
Authors: Wibisono Chablullah , Kenedi Jon , Astriani Fitri 
Published: October 2023

Radicalism in some societies can arise for many reasons. One of them is because of the need for more understanding of religion. This radicalism is the right target for people who aim to distort religious teachings or teach misguided religious ideas. People who are weak in performance are usually easily tempted by material inducements to do things that deviate from spiritual teachings. This study used Mix Method with Analysis Tool using AMOS version 24. Respondents and sample using the census method consisted of Members of the Riau Island Religious Harmony Forum (FKUB), totaling 135 Respondents. The results: The determination of the Ithiqomah on the Management of Religious Conflict is significantly positive, the Fanatics m resolution on the Management of Religious Conflict is highly positive, the Radicalism determination on the Management of Religious Conflict is very positive, the Management of Religious Conflict determination on Maslahah is a positive sign, the decision of the fanaticism on the Maslahah is positive important, the determination Radicalism on the Maslahah is positive but not significant, the determination isthiqomah on the Maslahah is positively influential. Square Multiple Correlation for Management of Religious Conflict =89.5%, Maslahah = 99.0%. It is suggested that there is no bias in understanding Radical and Radicalism. It is necessary to enlighten the people in the Riau Island Province. Fanatical is to hold strong, unwavering convictions in the face of evidence to the contrary, whether those convictions are positive or bad. Istiqomah is like having constancy, victory, courage, and glory in the conflict between obedience. When religious texts are understood superficially, they can birth to radical ideas and movements. Radicalism was used by national revolutionaries in the Western world to seize political power, as well as the flow used by anti-colonial nationalists and later used by social activists to achieve social goals.
Peran Japan Foundation Dalam Menjalankan Diplomasi Kebudayaan Jepang Di Indonesia Tahun 2015-2018
Authors: Aprilliyanto Ammar Fu’ad , Purwanto Adi Joko 
Published: October 2023

This research aims to determine how the Japan Foundation's role in carrying out Japanese cultural diplomacy in Indonesia in 2015-2018. As a result of colonial events in the past, Japan wanted to change its negative image in the eyes of the Indonesian people, besides that they conducted cultural diplomacy as well as to achieve their national interests. Therefore to launch the diplomacy process they formed the Japan Foundation in Indonesia. The research method used in this study is a qualitative method that is descriptive and analytical. This method seeks to describe the situation based on existing realities and is supported by theories and concepts that are used in order to be able to describe research precisely the nature, circumstances and symptoms, as well as supported by literature study, and online search. Theoretical foundation used is role theory. The results of this research indicate that the Japan Foundation has a significant role in fulfilling Japan's national interests. The role of the Japan Foundation as an Instrument for the Exchange of Art and Culture, as a Place for Japanese Language Education and Learning, as a Japanese Study Group and Intellectual Exchange creates an understanding between the people of Japan and the people of Indonesia so that it becomes an important factor in the development of diplomatic relations between Japan and Indonesia. So it can be concluded that the Japan Foundation is an important part of Japan's success in implementing the country's cultural diplomacy in Indonesia.
Vitamin D levels in nasopharyngeal carcinoma of the Minangkabau ethnic group
Authors: Rahman Sukri , Ali Hirowati , Indra Beni 
Published: October 2023

Background: Etiologi karsinoma nasofaring (KNF) sampai saat ini belum diketahui secara pasti, namun diduga merupakan interaksi dari multi faktor. Karsinoma nasofaring berhubungan erat dengan infeksi virus Epstein-Barr (EBV) yang berinteraksi dengan kerentanan genetik dan faktor lingkungan. Berbagai penelitian telah melaporkan hubungan vitamin D dengan risiko berbagai kanker, namun sangat sedikit penelitian hubungannya dengan KNF. Objective: This study was conducted to analyze the association of level of vitamin D with nasopharyngeal carcinoma in the Minangkabau ethnic group. Methods: Penelitian ini merupakan studi potong lintang membandingkan kadar vitamin D (25(OH)D) plasma pasien baru KNF etnik Minangkabau yang berobat di Rumah sakit Dr. M. djamil Padang dengan plasma kontrol sehat. Result: Penelitian ini mendapatkan rerata kadar vitamin D pada kelompok KNF lebih tinggi dibandingkan dengan kelompok kontrol, Kadar vitamin D pada penelitian ini bervariasi baik pada kasus dan kontrol. Pada kelompok KNF Kadar vitamin D bervariasi dari 14,64 sampai 75,56 ng/ml, Sebagian besar kelompok KNF memiliki kadar vitamin D yang normal (69,6%), dan pada kontrol kadar vitamin D juga bervariasi dari 6,06 sampai 73,96 ng/ml, dan sebagian besarnya juga dengan kadar normal (52,2%). Tidak terdapat perbedaan yang secara statistic bermakna antara kasus dan control (p>0,05). Conclusion: This study found no association between the level of vitamin D and the incidence of nasopharyngeal carcinoma in the Minangkabau ethnic group.
The 99 AI Challenge: Empowering a University Community through an Open Learning Pilot
Authors: Toane Carey , Doucette Lise , Rousseau Paulina , Serafin Michael , Spence Michelle , Kim Chris 
Published: October 2023

<p>While AI has entered the mainstream discourse in the past decade, teaching and research focusing on artificial intelligence are not new to the University of Toronto (U of T). As the home of the Vector Institute for Artificial Intelligence and the “godfather of deep learning,” Geoffrey Hinton, U of T, and the city of Toronto have a rich history in the field of artificial intelligence (AI) and have become a hub for AI research.1 However, many faculty, staff, and students are still in the dark about what AI is, how it works, and what implications it might have on their lives. While many departments at U of T offer AI courses and events, they are often aimed at those already engaged in this area of research or study who have a technical understanding of AI. </p>
Ідентифіковані уроки з розроблення доктрин планування: кількісний підхід до вимірювання повноти інформації
Authors: Коваль М. В. , Репіло Ю. Є. , Россійцев В. В. 
Published: October 2023

Вважається, що Збройні Сили України успішно запровадили військовий процес прийняття рішень (ВППР) під час підготовки у вищих військових начальних закладах та у військових частинах під час відновлення боєздатності. Простий підрахунок сторінок, відведених на етапи ВППР, показує, що доктрина ЗС України містить стільки ж аркушів, як і аналог СВ США. Однак результати опитування свідчать про незадоволеність офіцерів наявними документами. Це зумовило розроблення підходу, який уможливить точніше оцінювання повноти інформації доктрин ВППР ЗСУ порівняно із СВ США. Запропонований підхід дав змогу порівняти обсяги інформації доктрин.
За результатами вимірювання встановлено, що порівняно із СВ США в національних доктринах недостатньо інформації для ефективного використання ВППР. Визначено конкретний перелік процесів і процедур ВППР, інформації щодо яких не вистачає. Відсутність зазначеної інформації знижує ефективність використання ВППР у ЗС України, що підкреслює актуальність дослідження і потребу переопрацювання відповідних доктрин.
Brentuximab vedotin + AVD in cHL: cost impact on adverse events, toxicity, second malignancies, end-of-life and subsequent lines of therapy in Italy
Authors: Vassallo Chiara , Canali Beatrice , Fiorentino Francesca , Morelli Paolo , Ripoli Silvia , Fioravanti Laura 
Published: October 2023

Introduction: In classical Hodgkin lymphoma (cHL), the delayed effects of therapies, such as second malignancies and toxicity, and the high relapse rate are potentially associated with an expense for the National Health Service (NHS).
Objective: The objective of the study was to estimate the impact of introducing the combination of brentuximab vedotin (Adcetris®), doxorubicin, vinblastine and dacarbazine (A+AVD) for the first line (1L) treatment of stage III/IV cHL on costs associated with adverse events (AEs), pulmonary toxicity, second malignancies, end-of-life and second and subsequent lines (2L+) treatments.
Method: The incidence of the events analysed was derived from clinical trials and Italian reports. Unit costs were estimated based on the national tariffs and the Italian literature. The results were modelled and extrapolated to the population in two scenarios, a current one without A+AVD and a future one in which A+AVD is introduced. The time horizon was six years and the perspective is that of the Italian NHS.
Results: The introduction of A+AVD in 1L is associated with a reduction in the costs of AEs, pulmonary toxicity, second malignancies and end-of-life following 1L and in the acquisition costs of 2L+ treatments of approximately € 10,400/patient corresponding to a total saving of € 18.46 M over six years for the NHS; this saving grows as the use of A+AVD increases.
Conclusion: The introduction of A+AVD for the 1L treatment of stage III/IV cHL is associated with a reduction in costs for the NHS for the management of AEs, pulmonary toxicity, second malignancies, end-of-life and 2L+ treatments.
Ny bok: Whittaker K.J., Holmes, L., Del Valle J.F., & James, S. (red.) (2023)
Authors: Andersson Peter , Pålsson David 
Published: October 2023

Institutionsvård för barn och ungdomar (kollektiv vård och behandling dygnet runt) är en ofta ifrågasatt insats. Att föra samman barn med stora behov är förenat med risker och det finns ont om forskningsstudier som tydligt kan visa institutionsvårdens nytta för barns utveckling. Vårdformen präglas återkommande av skandaler och i Sverige rapporterades nyligen om våld och övergrepp vid Statens Institutionsstyrelses (SiS) särskilda ungdomshem. EU (Europeiska unionen) förordar “avinstitutionalisering” som överordnat mål och många länder, inklusive Sverige, prioriterar vård i familjehem framför institutioner. Samtidigt har institutionsvård en befäst position inom samhällsvård världen över. I Sverige är omkring vart fjärde barn i samhällsvård placerad vid ett HVB- eller SiS-hem. Svensk institutionsvård (SiS-hemmen undantagna) utförs på en löst sammanhållen marknad där vårdutbudet till stor del bestäms av privata aktörer.
I antologin Revitalizing residential care for children and youth. Cross-national trends and challenges (Oxford University Press, 2023) diskuteras institutionsvård i sexton västländer (inklusive Argentina). Boken gör nedslag i så skilda länder som USA, Spanien, Israel, Finland och Tyskland (dessvärre ingår inte Sverige i antologin). Syftet med boken är att ge en bild av hur institutionsvård används i olika länder, men även att identifiera framgångsrika praktiker.
MOVIMENTOS DE ACOPLAMENTO CORPO-SOLO NA POÉTICA DE ARTISTAS LATINO-AMERICANES
Authors: Marques Duarte Sarah 
Published: October 2023

O escrito dedica-se à observação de proposições artísticas que trabalham movimentos de aproximação corpo-terra. Tendo como interesse central práticas realizadas por artistas latino-americanes, o artigo objetiva investigar e relacionar ações que apostam em exercícios de acoplamento corpo-solo, entendendo-as como gestos de resistência ao silenciamento, anestesiamento, distanciamento e à espetacularização da vida própria ao projeto moderno/colonial capitalístico em sua versão contemporânea. Ações de escavação para a abertura de portais sensíveis, revolvendo a terra para escutar com as mãos, abrindo o corpo para ser canal. Artistas que criam alianças corpo-mundo, frestas para a emergência de sensibilidades outras, para escutas outras, vozes outras. Ações como de Ana Mendieta, Tania Bruguera, Seba Calfuqueo, Rodrigo Braga, Natália Lobo Tupinambá, Tieta Macau, entre outres, que investem em experiências de contato com o mundo como vivo, vibrando a experiência das forças do mundo em seus corpos como via de denúncia, mas também de anúncio, de configurações outras de vida sobre uma terra ferida. O trabalho articula descrições e análises de propostas com reflexões desenvolvidas pelos artistas em diálogo com ideias de autores como Maria Lugones, Fernanda Eugénio, Suely Rolnik, Ailton Krenak, Peter Pál Pelbart, entre outres.
Five-years post commercial approval monitoring of eucalyptus H421
Authors: Pinheiro Ana Cristina , dos Santos Anselmo Azevedo , Avisar Dror , Gonsalves José Mateus , Galan Maria Paula , Abramson Miron , Barimboim Noga , Abrahão Othon , Graça Rodrigo Neves , Drezza Thaís Regina , Silva William 
Published: October 2023

Eucalyptus comprises the largest planted area of cultivated production forest in Brazil. Genetic modification of eucalyptus can provide additional characteristics for increasing productivity, protecting plant yield, and potentially altering fiber for various industrial uses. With this objective, a transgenic eucalyptus variety, event H421, received regulatory approval for commercial release after 6 years of approved risk assessment studies by the Brazilian National Technical Biosafety Commission (CTNBio) in 2015, becoming the first approved genetically modified (GM) eucalyptus in the world. GM event H421 enables increased plant biomass accumulation through overexpression of the Arabidopsis 1,4-β-endoglucanase Cel1, which remodels the xyloglucan–cellulose matrix of the cell wall during development to promote cell expansion and growth. As required, in that time, by the current normative from CTNBio, a post-commercial release monitoring plan for H421 was submitted, incorporating general surveillance for five consecutive years with the submission of annual reports. The monitoring plan was conducted on fields of H421 progenies, with conventional clones as comparators, cultivated in representative regions where eucalyptus is cultivated in the states of São Paulo, Bahia, and Maranhão, representing Southeast, Northeast, and Northern Brazil. Over the course of the five-year general surveillance monitoring plan for the approved GM eucalyptus H421, no adverse effect that could impact the biosafety of the commercially approved event was identified. Additionally, the GM eucalyptus exhibited behavior highly consistent with that of conventional commercial clones. Therefore, there was no need for an extra risk assessment study of a case-specific monitoring plan. The results show the importance of continuously updating the regulation norms of governmental agencies to align with scientific advances.
The association between thyroid-stimulating hormone and thyroid nodules, goiter and thyroid antibody positivity
Authors: Li Shaohan , Guo Wenxing , Meng Qi , Zhu Mei , Wei Hongyan , Ji Fengying , Tan Long , Zhang Wanqi 
Published: October 2023

BackgroundThe relationship between normal thyroid-stimulating hormone (TSH) levels and thyroid disease in adults remains controversial. This study aimed to investigate the correlation between serum TSH levels, particularly those falling within the normal range, and thyroid diseases in Chinese adults, including thyroid nodules (TN), goiter (GR), and thyroid antibody positivity.Materials and methodsThis research was a cross-sectional study conducted in an adult population in Tianjin, China. Thyroid volume (Tvol) and TN were assessed using thyroid ultrasonography. Fasting venous blood and spot urine samples were collected to evaluate thyroid function and iodine status.ResultsA total of 2460 subjects participated in the survey. The prevalence of thyroid dysfunction was 9.76%, and abnormal TSH levels were found to potentially increase the risk of GR and thyroid antibody positivity in adults. A total of 2220 subjects with TSH within the normal reference range were included in the further study. In these patients, Tvol decreased as TSH levels increased, in both men and women (P &lt; 0.0001). Low TSH levels (0.27–1.41 IU/mL) were identified as a risk factor for TN (odds ratio [OR], 1.46; 95% CI: 1.14-1.87) and GR (OR 5.90, 95% CI 2.27-15.3). Upon stratification by sex and age, the risk of TN was found to be higher in women and elderly individuals (≥60 years old), while the risk of GR was found to be higher in men and younger individuals (&lt;60 years old). High TSH levels (2.55–4.2 IU/mL) were identified as a risk factor for thyroid antibody positivity (OR, 1.53; 95% CI: 1.11-2.10). Men and younger individuals with high TSH levels exhibited a higher risk of thyroid antibody positivity.ConclusionIn adults with normal TSH levels, low TSH levels were associated with an increased risk of TN and GR, whereas high TSH levels were associated with thyroid antibody positivity. The research also suggests that adults whose TSH levels at upper or lower limits of the normal range should be reviewed regularly.
Dissolved oxygen concentration inversion based on Himawari-8 data and deep learning: a case study of lake Taihu
Authors: Shi Kaifang , Lang Qi , Wang Peng , Yang Wenhao , Chen Guoxin , Yin Hang , Zhang Qian , Li Wei , Wang Haozhi 
Published: October 2023

Dissolved Oxygen (DO) concentration is an essential water quality parameter widely used in water environments and pollution assessments, which indirectly reflects the pollution level and the occurrence of blue-green algae. With the advancement of satellite technology, the use of remote sensing techniques to estimate DO concentration has become a crucial means of water quality monitoring. In this study, we propose a novel model for DO concentration estimation in water bodies, termed Dissolved Oxygen Multimodal Deep Neural Network (DO-MDNN), which utilizes synchronous satellite remote sensing data for real-time DO concentration inversion. Using Lake Taihu as a case study, we validate the DO-MDNN model using Himawari-8 (H8) satellite imagery as input data and actual DO concentration in Lake Taihu as output data. The research results demonstrate that the DO-MDNN model exhibits high accuracy and stability in DO concentration inversion. For Lake Taihu, the performance metrics including adj_R2, RMSE, Pbias, and SMAPE are 0.77, 0.66 mg/L, −0.44%, and 5.36%, respectively. Compared to the average performance of other machine learning models, the adj_R2 shows an improvement of 6.40%, RMSE is reduced by 8.27%, and SMAPE is decreased by 12.1%. These findings highlight the operational feasibility of real-time DO concentration inversion using synchronous satellite data, providing a more efficient, economical, and accurate approach for real-time DO monitoring. This method holds significant practical value in enhancing the efficiency and precision of water environment monitoring.
Material identification and heavy metal characteristics of plastic packaging bags used in Chinese express delivery
Authors: Jiang Yinhua , Song Guanghan , Zhang Hui 
Published: October 2023

With the rapid development of China’s express delivery services, environmental concerns have increased owing to the use of plastic packaging bags (PPBs) which have a heavy metal (HM) content due to the incorporation of scrap plastics in the production process. We sourced a variety of PPBs from different express delivery parcels, identified the materials in the samples using Fourier-transform infrared spectrometry, and conducted HM analysis using inductively coupled plasma mass spectrometry. The results demonstrated that the main material type in the PPBs was polyethylene. The results showed that the potential health concerns were posed by the four HMs (nickel [Ni], copper [Cu], zinc [Zn], and arsenic [As]) presented in the PPB samples. The mean concentrations of HMs in the PPBs were ranked as follows (presented in unit mg kg−1): Zn (120.42 ± 85.15)&gt; Cu (45.21 ± 56.55) &gt; lead [Pb] (6.43 ± 6.57) &gt; Cr (6.03 ± 6.82) &gt; Ni (2.13 ± 2.14) &gt; As (0.19 ± 0.15) &gt; mercury [Hg] (0.17 ± 0.71) &gt; cadmium [Cd] (0.14 ± 0.20). HM content varied according to sample type, with a ranking order of Rm &gt; Pm &gt; Bm, corresponding to the degree of environmental and health risk. For Rm samples, high levels of low-toxicity HMs, such as Zn and Cu were detected, with respective maximum values of 365.9 and 184.2 mg kg−1; furthermore, the levels of high-toxicity HMs (i.e., Cd and Hg) exceeded the standard values set by the express delivery sector (0.5 mg kg−1). Thus, more attention should be paid to the effective management of PPBs for polyethylene-based Rm types, such as the limitation of Zn, Cu, Cd, and Hg. This study provides baseline data regarding HM-incorporating PPBs for stakeholders and is expected to support the formulation of relevant products for use in greener packaging policy and, thus, contributes to the re-assessment of China’s “plastic ban” policy.
Incidental finding at methylation-specific multiplex ligation-dependent probe amplification (MS-MLPA): how to proceed?
Authors: Manero-Azua Africa , Pereda Arrate , Llano-Rivas Isabel , Garin Intza , Perez de Nanclares Guiomar 
Published: October 2023

Introduction: Since the advent of new generation sequencing, professionals are aware of the possibility of obtaining findings unrelated to the pathology under study. However, this possibility is usually forgotten in the case of studies aimed at a single gene or region. We report a case of a 16-month-old girl with clinical suspicion of Silver-Russell syndrome (SRS).Methods: Following the international SRS consensus, methylation alterations and copy number variations (CNVs) at 11p15 region and maternal uniparental disomy of chromosome 7 were analysed and discarded by MS-MLPA.Results: Unexpectedly, the 11p15 region MS-MLPA showed a decrease in the signal of a copy number reference probe. Deletions affecting a single probe are inconclusive. So, we faced the ethical dilemma of whether it was appropriate to confirm this alteration with independent techniques and to offer a diagnostic possibility that was in no way related to clinical suspicion. Fortunately, in this particular case, the informed consent had not been specific to a particular pathology but to any disorder associated with growth failure. Performed alternative studies allowed the final diagnosis of 22q deletion syndrome.Conclusion: We demonstrate the importance of informing patients about the possibility of obtaining incidental findings in genetic techniques (not only in next generation sequencing) during pre-test genetic counselling consultations. In addition, we highlight the relevance of including in the informed consent the option of knowing these unexpected incidental findings as in some cases, this will help to elucidate the definitive diagnosis and provide the correct follow-up and treatment.