bluuebunny/crossref_metadata_2025_split huggingface dataset:
Following changes in balance and cognitive performance on healthy middleaged people: Evaluation of the effect of two types of concurrent training
Authors: Canli Umut , Prieto-González Pablo 
Published: December 2023

Purpose.The study aimed to compare the effects of two different concurrent training protocols applied to healthy middleaged individuals on balance parameters and cognitive functions.Methods.Thirty-three middle-aged adults voluntarily participated in this study. A randomised, between-group design (Strength+Aerobic Group [SAG] and control group Aerobic+Strength Group [ASG]) was used. After collecting data related to the main characteristics of the subjects (i.e., age, sex, medical history, smoking habits), the following assessments were made: Subjects’ physical activity level, balance parameters, and inhibition and attention indicators. The intervention lasted 13 weeks (2 sessions per week, 50 minutes per session).Results.Both protocols (SAG and ASG) significantly improved balance performance. However, as for the group-by-time interaction, no significant difference between the two groups were observed in any of the parameters assessed (F(1–31) = 0.843; 0.760; 0.612; 0.656; <i>p</i> > 0.05). Thus, it was found that participating in either the SAG or ASG groups had no significant influence on attention accuracy, reaction time, total number of matters processed (participants’ psychomotor speed), and non-marked letters (selective attention) (post-test–pre-test difference: F(1–31) = 0.239, 0.337, 0.738, 0.414; <i>p</i> > 0.05). It was also observed that both training programs resulted in similar improvements in all balance characteristics and cognitive parameters.Conclusions.It was found that the order of strength or aerobic exercises in the concurrent training for improving balance and cognitive parameters in healthy middle-aged individuals is not significant.
What Is the Vital Force? Towards a Quantum Perspective on Vitalism and Possible Consequences for CAM.
Authors: Milgrom Lionel 
Published: December 2023

A brief history of vitalism is followed by a description of the scientific paradigm and the relationship of information to quantum theory. Quantum Bayesianism (QBism) is introduced as an alternative subjective interpretation of quantum theory, and a better descriptor of the therapeutic process (TP) than previous objective conventional quantum theoretical (CQT) interpretations. The vital force (Vf) is considered a system defined solely by observations of a patient’s (Px’s) secondary symptoms (S2) during case-taking, and changes to them (DS2) after treatment. This is combined with a previous gyroscopic metaphor of the Vf. According to QBism, wave functions generated by this metaphor depend on subjective degrees of belief in observations of S2 and DS2. As such, assessing a Px’s S2 and DS2 not only changes over time but may well differ from another’s assessment of the same Px. Conclusion: Treating the Vf as an analogue of the quantum state of a macroscopic system, i.e., Px, represents all that can possibly be known about a Px’s symptoms by observation, not the Vf’s presumed reality, separate from an observer. The Vf is simply a representation of knowledge about Px, suggesting how a subjective generally valid quantum metaphor for the TP might develop in future.
Physical transfer of the UHD signal resulting from potentized dilution of interferon gamma antibodies
Authors: Jerman Igor , Ogrizek Linda , Jan Luka , Periček Vesna 
Published: December 2023

Physico-chemical examinations of very high dilution (UHD) solutions subjected to certain physical factors (such as shaking) are becoming more frequent and are increasingly producing conclusive results. A much less studied phenomenon is the transfer of molecular information (UHD signals of diluted substances) from one liquid to another without an intermediate liquid phase. The aim of this study was to investigate the possibility of such a transfer of the UHD signal from the UHD solutions to the receiver solution, in particular, if the molecular source used in the donor solutions was the biologically active interferon gamma antigen molecule. We were especially interested in how the transfer of the UHD signal is affected by the time of exposure of the receiver to the donor, and how the transfer is affected by activation (shaking) versus exposure alone.
For measurement of the physicochemical parameters, we used pH, electrical conductivity, and oxidation-reduction potential (ORP) sensors. For relative UV/VIS spectroscopy measurements, we used a Macherey-Nagel spectrophotometer. All original liquids (water and solutions, four different liquids altogether) subject to research were obtained from Materia Medica LTD, Moscow. Distilled water (W) was used for dilutions and potencies as follows: potentized water (W cH9), potentized dilution of antibodies to interferon-gamma (Abs IFNγ cH9), the same original substance in the form of a mixture of potencies (Abs IFNγ cH12, cH30, cH50, shortly Abs IFNγ mix). We used two different receiver solutions, one for physicochemical research and another (addition of alcohol) for UV/VIS spectroscopy. The transfer of UHD signal via glass was processed via shaking of the donor flask. For direct or post-hoc analysis, we used Wilcoxon signed-rank test, two tailed. The results showed that activation strongly influences signal transfer and that this can be compensated to some extent by prolonged direct exposure. In principle, exposure time has a positive effect on signal transfer. Although the detection of the physically transmitted signal is generally weaker than the signal in the original UHD solutions, it is still detectable with our measurement system and protocol, both in terms of effect (Cohen's D) and statistically significant differences. In this respect, different detection methods may detect the signal differently. After the separation between the donor and receiver glasses (solutions), the character of the signal may change and may even be better expressed. Activation is shown to be an important factor for the UHD signal transfer, at least for shorter times. By longer exposure times, it appears that activation can be compensated, at least to some extent.
A Cantharis potency acts on heat exposed bovine serum albumin as revealed by FT-IR spectroscopy
Authors: Sukul Nirmal , Singh Raj Kumar , Pande Nivedita , Sukul Anirban 
Published: December 2023

In a series of experiments we have demonstrated that high dilution of homeopathic drugs produces distinct effects on plants and animals in-vivo through the medium of water. High dilutions (HDs) of a drug prepared by serial dilution with a solvent medium 1:100, followed by mechanical agitation in several steps are called potencies. Water molecules play an important role on protein structure and function. We focused our observation on water molecules associated with BSA. High dilution (HD) of a homeopathic drug is thought to be specific water structure which produces therapeutic effects on man. HDs also produce effects on animals, plants and even proteins in aqueous solution. What is the primary target of HDs on organisms or on protein? The present study addresses this question. Cantharis 30 cH, a homeopathic potency used for burn injuries, has been tested on bovine serum albumin (BSA) in-vitro. The protein has been exposed to heat at 750C for 10 mins, cooled down to room temperature and then treated with Cantharis 30 cH. The treatment was done by two methods, direct and indirect through water. The results from both the methods are almost similar. The treated and untreated protein solutions were analysed by Fourier Transform Infra-Red (FT-IR) spectroscopy. The treatment effect was evident on water molecules associated with BSA. The results indicate that Cantharis 30 cH interacts with water molecules which in turn influence BSA. It is concluded that the homeopathic potency converts first water structure which then affects the protein. Based on the results on this experiment we can assumes that the primary target of all homeopathic potencies is water which constitutes the major component of all living organisms. All biomolecules are suspended in water.
Need for external replication trials in homeopathic basic research: presenting research on three duckweed test systems as an example
Authors: Ücker Annekathrin 
Published: December 2023

One of the main aims in homeopathic basic research is to find reliable test systems that are externally replicable. In face of the replication crisis in research in general and the specificities that are necessary to include in homeopathic basic research, it is of great importance to encourage high-quality replication trials. One way to achieve that is to build up a register or a data base for test systems in homeopathic basic research that are already developed to the point that external replication trials are possible. Such a register offers the opportunity to include not just the published information but also helpful insight such as material lists and time frames for easier planning and conduction of replication trials. Additionally, further information on critical environmental parameter, unpublished negative results, etc. could be included.
The general frame work of such a register/ data base is demonstrated with the example of three different duckweed test systems developed in our working group since 2001. The growth rate of duckweed (Lemna gibba L., clone number 9352) was investigated in randomised and blinded settings, using either untreated plants or plants pre-treated with a stressor (arsenic solution or calcium deficiency in the growth medium). Within the original trials, potentised substances in the range of 14x-33x were compared to water control groups (succussed and unsuccussed water). The stability of the test systems was investigated in parallel systematic negative control (SNC) experiments. All original trials revealed a significant influence of some potencies on the growth rate of duckweed and stable test systems as shown with SNC experiments. Four internal replication trials for two of the three test systems were conducted. The replication trials showed effects of homeopathic preparations with some differences in effect size and effect direction compared to original studies.
In vitro evaluation of Sporothrix brasiliensis biotherapic: complete results
Authors: Moreno Barbosa Gleyce , Ribeiro Ricardo Brito Amanda , Barbosa da Silva Moura Paloma , Da Silva Faria Camily , Cavalcanti dos Santos Velasco de Souza Lais , Machado Rocha Leandro , Regina de Souza Baptista Andrea 
Published: December 2023

Background: Sporothrix brasiliensis is a fungus that affects animals, mainly felines, and humans. The infection can present as subcutaneous or disseminated form in the organism. Rio de Janeiro, Brazil, is a state with high prevalence of cases in felines. Currently, the standard treatment is realized during a long period and using itraconazole, that causes important adverse effects. Objective: The aim of this research was to evaluate in vitro effect of Sporothrix brasiliensis biotherapic in the fungus used to prepare this medicine, also considering the association to itraconazole. Methodology: Yeast cells of S. brasiliensis (ATCC MYA 4823) were cultured in Brain Heart Infusion (BHI) during 3 to 5 days. The biotherapic 30 DH was prepared according to Brazilian Homeopathic Pharmacopoeia, using 5 x 107 yeasts/mL. Two biotherapics were prepared: using inactivated fungus by autoclave (Sb1) and viable yeasts (Sb2). Both biotherapics were evaluated individually and associated to itraconazole. The control groups were: water, diluted water, water 30 DH, and dimethylsulfoxide (vehicle to dissolve itraconazole), and itraconazole. The minimum inhibitory concentration (MIC) experiments were carried out, considering the CLSI (Clinical & Laboratory Standards Institute) guidelines. Results: The treatments using only biotherapic did not reduced the yeast viability, as observed in the controls. However, the higher concentrations of itraconazole and of this drug associated with biotherapic reduced the viability of S. brasiliensis. Then, the observed effect was attributed to itraconazole. Conclusion: As expected, it was not detected the effect of both biotherapic in the viability of microorganism itself, due to the integrality aspects of homeopathy, because the homeopathic medicine emphasizes the whole organism’s response to the symptoms presented. Then, the next step is to evaluate the biotherapic in an in vivo model, that will be a complete organism representing the host to this infection.
Prevalence of Depression and Burnout among Family Medicine Residents in Riyadh City, Saudi Arabia
Authors: AlNahedh Alaa , BinRusayyis Asma , Al-Tannir Mohamad , AlFayyad Isamme 
Published: December 2023

Background The mental health of healthcare workers, particularly family medicine residents, is an area of growing concern, more so in the context of the COVID-19 pandemic. High levels of burnout and depression among these professionals can affect their well-being and patients’ quality of care. Objectives The study aimed to determine the prevalence of depression and burnout among family medicine residents in Riyadh, Saudi Arabia. Materials and Methods A cross-sectional study was conducted among 213 family medicine residents, using a self-administered survey. The survey included the Maslach Burnout Inventory and the Patient Health Questionnaire (PHQ)-9 to assess burnout and depression. Descriptive statistics were used to summarize participants’ characteristics, and regression model was developed to explore predictors of burnout and depression. Results The mean age of participants was 26.85±1.42 years, and 53.3% were males. The study found a high prevalence of emotional exhaustion (EE) and depersonalization (DP) among participants, with mean scores of 21.10±9.38 and 15.44±7.69, respectively, indicating moderate to high levels. Similarly, a high level of personal accomplishment (PA) was reported, with a mean score of 11.46±6.33. Around 10% of participants reported moderately severe and severe depression, with a mean PHQ-9 scale score of 6.03±5.10. Gender and depression severity were significantly associated with burnout (p=0.001 and p<0.001, respectively). Conclusion The study underscores a significant prevalence of burnout and depression among family medicine residents in Riyadh, with notable variations across different demographic and professional characteristics. This necessitates tailored mental health interventions for this population, especially in challenging times like the ongoing pandemic.
Kronik Obstrüktif Akciğer Hastalarında COVID-19’un Günlük Yaşam Aktiviteleri ve Hastalık Semptomları Üzerine Etkisi
Authors: ÖZDEMİR Neşe , ALKAN Halil 
Published: December 2023

Amaç: Bu araştırma, kronik obstrüktif akciğer hastalarında COVID-19’un günlük yaşam aktiviteleri ve hastalık semptomları üzerine etkisini incelemek amacıyla yapıldı.
Materyal ve Metot: Tanımlayıcı, kesitsel türde yapılan araştırma Haziran 2022- Eylül 2022 tarihleri arasında X Devlet Hastanesi Göğüs Hastalıkları polikliniğe başvuran 199 KOAH hastası ile yürütüldü. Araştırmanın verileri; Hasta Tanılama Formu, KATZ Günlük Yaşam Aktiviteleri Ölçeği (GYAÖ), KOAH Değerlendirme Testi (CAT), Değiştirilmiş Tıbbi Araştırma Konseyi (MMRC) ölçeği ile toplandı.
Bulgular: COVID-19 geçiren KOAH’lı hastalar ile COVID-19 geçirmeyen KOAH hastaların günlük yaşam aktiviteleri ve hastalık semptom düzeyleri karşılaştırıldığında GYA ve CAT toplam skorları açısından istatistiksel olarak fark bulundu (p0.05).
Sonuç: COVID-19 geçiren KOAH’lı hastalar COVID-19 geçirmeyen KOAH hastalarına göre daha düşük GYA’ya sahip olmakla birlikte, daha şiddetli hastalık semptom düzeylerine (nefes darlığı, öksürük, balgam, uyuma, yorgunluk gibi) sahip olduğu belirlendi. COVID-19 geçiren KOAH’lı hastalar daha uzun süreli takip edilerek hastalık semptomlarını azaltma ve GYA geliştirme açısından daha fazla desteklenmelidir.
Analysis of mother's knowledge level in special location areas for stunting prevention
Authors: Salim Andi , Muslimin Irma , Rahim Rachmawati , Atalla Sohayla M. , Chen Hana W. Jun , Kumar Kavitha Ashok 
Published: December 2023

This research aims to analyze more deeply the knowledge that mothers have about stunting and pregnancy in areas with special locations for stunting prevention.. This research was designed by compiling a structured questionnaire consisting of 2 groups of questions, namely knowledge questions about stunting consisting of 14 questions and questions about pregnancy consisting of 21 questions. Each question is given a score and then formulated to get the final scoring for each respondent. The research results show that the average value of respondents' knowledge about stunting was 3.36 and the average value of respondents' knowledge about pregnancy was 13.70. After being categorized based on the average value, the average knowledge of respondents regarding stunting was 52% in the sufficient category, and respondents' knowledge about pregnancy was 66% in the sufficient category. However, increasing maternal knowledge about stunting and pregnancy needs to be increased to 100% to be the basis for preventing stunting in the future.
The CO2 Conversion in a DBD Plasma: A 1D Synergistic Catalysis Model
Authors:   State Key Lab of Advanced Electromagnetic Engineering and Technology, School of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan, Hubei Province, China, Cheng He ,   School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu Province, China, Lei Xiaoting ,   School of Chemistry and Chemical Engineering, Nanjing University of Science and Technology, Nanjing, Jiangsu Province, China, Lu Xinpei ,   State Key Lab of Advanced Electromagnetic Engineering and Technology, School of Electrical and Electronic Engineering, Huazhong University of Science and Technology, Wuhan, Hubei Province, China
Published: December 2023

Objective: Plasma catalysis is regarded as a promising technology in mitigating atmospheric CO2, but there is still a gap between industrial demand and current efficiency. This paper aimed to investigate the synergistic effect between vibrational states and catalyst surfaces in plasma catalysis, and to offer a theoretical guide on how to maximize the effectiveness of the synergistic effect in a more energy-efficient way. Methods: A novel 1D dielectric barrier discharge plasma catalysis model has been developed. The Arrhenius equations were used to solve the surface catalytic chemistry. The influence of CO2 vibrational excitation on surface reaction rates were expressed in the framework of the theoretical-informational approach. Results: The simulation suggested that a lower electron temperature fosters vibrational excitation, while a higher electron temperature promotes electronic excitation, therefore, the CO2 conversion rate and energy efficiency were difficult to be improved simultaneously. Furthermore, our model elucidates the pivotal role of catalysts in achieving efficient decomposition of vibrationally excited CO2 (CO2v). However, under conditions of low vibrational density, this synergistic effect fails to yield substantial improvements in catalytic efficiency under low vibrational density conditions. Conclusion: By increasing the pulse voltage, using narrow pulses with rapid rise times, implementing rapid cooling techniques and enlarging the surface catalytic area, the concentrations of CO2v can be augmented. Consequently, the dissociation rate via the V-V process and surface processes can both be enhanced, thereby potentially enabling simultaneous improvements in the CO2 conversion rate and energy efficiency.
Analysis of the chemical composition of lipophilic fractions of the hepatoprotective and antimicrobial herbal collections
Authors: Юсупова А.А. , Баймухаметов И.Р. , Кудашкина Наталья Владимировна , Хасанова Светлана Рашитовна 
Published: December 2023

В статье приведены результаты исследования по идентификации химического состава липофильных фракций из гепатопротекторного и противомикробного сборов. Разделение и идентификацию компонентов липофильных фракций проводили методом газовой хроматографии с масс-спектрометрическим детектором. Идентификацию летучих компонентов проводили по совпадению с библиотечными масс-спектрами. В составе липофильных фракций идентифицировано всего 25 соединений. Присутствие в противомикробном сборе цинеола, анетола обусловливает наличие антимикробных и отхаркивающих свойств, а ?-ситостерола – гипохолистеринемического, антибактериального, противовирусного и противогрибкового действия. Присутствие в гепатопротекторном сборе ментона обусловливает спазмолитические, обезболивающие и антисептические свойства, куркумина – антиоксидантные, противовоспалительные, противовирусные, болеутоляющие, антимикробные и противораковые, а бисаболола оксида А – противовоспалительные.
The article presents the results of a study on the identification of the chemical composition of lipophilic fractions from hepatoprotective and antimicrobial preparations. The separation and identification of the components of lipophilic fractions was carried out by gas chromatography with a mass spectrometric detector. Volatile components were identified by coincidence with library mass spectra. Only 25 compounds were identified in the composition of lipophilic fractions. The presence in the antimicrobial collection of cineol, anethole determines the presence of antimicrobial and expectorant properties, and B-sitosterol - a hypocholesterolemic effect. The presence of menthon in the hepatoprotective collection causes antiseptic, analgesic and antispasmodic properties. Curcumin in the composition of the collection has a powerful antioxidant effect, and bisabolol oxide A has an anti-inflammatory effect.
Análise sobre a coleta seletiva de resíduos sólidos por meio da logistíca reversa durante a pandemia da Covid-19 no município de Porto Nacional – TO
Authors: Pereira Filho Albano Dias , Oliveira Cynthia Souza , Geller Marlise , De Sousa Lilissanne Marcelly 
Published: December 2023

A presente pesquisa teve como objetivo realizar uma análise em relação ao processo de materiais recicláveis na logística reversa durante a pandemia da COVID-19 no Município de Porto Nacional – TO. Buscou-se fazer levantamentos sobre como os materiais recicláveis que estão sendo utilizados durante esse processo de pandemia estão recebendo o destino correto. pesquisa apresenta dados qualitativos, de natureza “básica”, em relação aos procedimentos técnicos se caracteriza como de “levantamentos” e no que condiz aos fins se classifica como “descritiva”. Para a análise de dados foi elaborado um questionário com perguntas abertas e fechadas, a própria pesquisadora foi ao encontro do entrevistado para realizar a pesquisa, o questionário conta com o total de 7 perguntas. Identificou-se nesta pesquisa que, existem os cuidados segundo a Agência Estadual de Vigilância Sanitária, tais como proteção individual, adotados em relação aos materiais de proteção como máscaras, luvas e lenços descartáveis, que devem ser acondicionados em sacos específicos devidamente lacrados, identificados e borrifados com solução desinfetante. Entendemos que a prefeitura de Porto Nacional e a empresa responsável pela coleta seletiva, precisa externar tanto para população, quanto para seus funcionários as diretrizes técnicas e jurídicas para a coleta seletiva e triagem de materiais recicláveis durante a pandemia de Covid-19, uma vez que este documento norteia a visão de atuação resolutiva do Ministério Público, nos termos das recomendações do Conselho Nacional do Ministério Público, o conteúdo desse documento foi desenvolvido a partir de debates ocorridos em reuniões amplas e abertas realizadas pelo Ministério Público.