bluuebunny/crossref_metadata_2025_split huggingface dataset:
OPTIMIZATION OF ANTIHYPERTENSIVE THERAPY, TAKING INTO ACCOUNT INDIVIDUAL AGE-ASSOCIATED DISORDERS
Authors: Гафанович Е.Я. , Львович А.И. , Чернов А.В. 
Published: October 2023

В статье рассматриваются вопросы, связанные с использованием оптимизированного подхода для выбора индивидуальной антигипертензивной терапии у пациентов старшего и пожилого возраста. Ориентация на старшие возрастные группы требует наряду с необходимостью нормализации артериального давления стабилизации возраст-ассоциированных состояний. Показано, что в этом случае необходимо учитывать соответственно две группы показателей. В качестве второй группы рассматриваются показатели, определяемые на основе тестов, которые характеризуют уровень когнитивных нарушений. Выбор оптимальной тактики лечения основан на предварительном анализе ретроспективной информации в форме статистических выборок значений показателей и факторов, оказывающих влияние на эти показатели в процессе антигипертензивной терапии. С использованием методов машинного обучения формируются связанные модели как для классификации вариантов лечения по их эффективности, так и прогностической оценке влияния индивидуальных характеристик пациента на выполнение требований к показателям двух групп. Оптимизационные процедуры выбора индивидуальной тактики лечения возраст-зависимых больных построены с ориентацией на формы связанных моделей и сочетания экстремальных и граничных требований к показателям эффективности антигипертензивной терапии с ограничением количества лекарственных препаратов
The paper deals with the use of an optimized approach for the selection of individual antihypertensive therapy in elderly and elderly patients. Orientation to older age groups requires, along with the need to normalize arterial pressure, the stabilization of age-associated conditions. It is shown that in this case it is necessary to take into account two groups of indicators, respectively. As the second group, indicators determined on the basis of tests that characterize the level of cognitive impairment are considered. The choice of optimal treatment tactics is based on a preliminary analysis of retrospective information in the form of statistical samples of the values of indicators and factors influencing these indicators in the process of antihypertensive therapy. Using machine learning methods, linked models are formed both for classifying treatment options according to their effectiveness and for predictive assessment of the impact of individual patient characteristics on meeting the requirements for indicators of the two groups. Optimization procedures for choosing individual tactics for the treatment of age-related patients are based on the forms of related models and a combination of extreme and boundary requirements for the effectiveness of antihypertensive therapy with a limitation of the number of drugs
PRIORITY AREAS FOR THE BEST CORPORATE PROGRAMS AND PRACTICES FOR A HEALTHY LIFESTYLE
Authors: Ковалев С.П. , Яшина Е.Р. , Ушаков И.Б. , Турзин П.С. , Лукичев К.Е. , Лупанов А.И. 
Published: October 2023

В настоящее время в Российской Федерации активно разрабатываются и внедряются корпоративные программы и практики формирования здорового образа жизни. В статье представлены лучшие примеры корпоративных программ и практик, реализуемых ведущими отечественными и зарубежными компаниями.Приведена структура типовой корпоративной программы по поддержке здорового образа жизни работников. Отражена высокая медицинская результативность, социальная и экономическая эффективность применения корпоративных программ по укреплению здоровья работников предприятий в стране. Статья подготовлена в рамках выполнения научно-исследовательской работы государственного задания РАНХиГС
Currently, corporate programs and practices of healthy lifestyle formation are being actively developed and implemented in the Russian Federation. The article presents the best examples of corporate programs and practices implemented by leading domestic and foreign companies. The structure of a typical corporate program to support a healthy lifestyle of employees is given. The high medical efficiency, social and economic efficiency of the use of corporate programs to strengthen the health of employees of enterprises in the country are reflected. The article was prepared as part of the research work of the state task of the RANEPA
UPAYA PENINGKATAN COLLABORATION SKILLS MELALUI PEMBELAJARAN PROBLEM BASED LEARNING (PBL) di KELAS V SDN TINGKIR TENGAH 02 SALATIGA
Authors: Muhammad Iqbal Maruf  , Mawardi  
Published: October 2023

ABSTRACT
The research was conducted with the aim of improving collaboration skills in 5th grade elementary school students using the Problem Based Learning (PBL) instructional model. The study took place at SDN Tingkir Tengah 02 Salatiga in the first semester of the 2023/2024 academic year, with a total of 28 students. This research is a Classroom Action Research with non-test data collection techniques, and quantitative data analysis. The instrument used was an observation sheet for collaboration skills. The research consisted of two cycles. The results of the research showed that the Problem Based Learning instructional model can enhance collaboration skills. This was evidenced by the pre-cycle data, where only 32.14% of the fifth-grade students exhibited good collaboration skills, while 67.86% were still lacking in collaboration skills. In the first cycle, there was an increase to 53.57% of students with good collaboration skills, while 46.43% of students still had insufficient collaboration skills. In the second cycle, there was a further improvement, with 82.57% of students demonstrating good collaboration skills, and 17.43% of students still lacking in collaboration skills. This improvement was evident in changes in student behavior, as students in the pre-cycle appeared to prefer working individually, but after the implementation of this model, students were very enthusiastic about collaboration.

Keywords: Collaboration Skills, Problem Based Learning (PBL)
ABSTRAK
Penelitian dilaksanakan dengan tujuan untuk meningkatkan collaboration skils pada siswa kelas 5 Sekolah Dasar dengan menggunakan model pembelajaran Problem Based Learning (PBL). Penelitian dilaksanakan di SDN Tingkir Tengah 02 Salatiga pada kelas 5 Semester 1 tahun pelajaran 2023/2024 dengan jumlah siswa 28 orang. Jenis penelitian ini adalah Penelitian Tindakan Kelas dengan teknik pengumpulan data nontes, analisis data berupa kuantitatif. Intrumen yang digunakan adalah lembar observasi collaboration skills. Penelitian dilaksanakan dua siklus. Hasil penelitian menunjukkan bahwa model pembelajaran Problem Based Learning dapat meningkatkan collaboration skills. Dibuktikan dengan data pra siklus dari 28 siswa kelas 5 hanya 32,14% siswa yang collaboration skills baik, sedangkan 67,86% masih kurang dalam collaboration skills. Pada siklus I mengalami kenaikan menjadi 53,57% siswa dengan collaboration skills baik, sedangkan untuk siswa yang kurang dalam collaboration skills menjadi 46,43%, pada siklus II mengalami peningkatan menjadi 82,57% siswa dengan kemampuan collaboration skills yang baik dan 17,43% siswa yang masing kurang dalam collaboration skills. Peningkatan tersebut nampak pada perubahan perilaku siswa dimana siswa pada pra siklus terlihat lebih memilih bekerja secara individu sedangkan setelah penerapan model ini siswa sangat antusias untuk berkolaborasi.

Kata Kunci: Collaboration Skills, Problem Based Learning (PBL)
HUBUNGAN ANTARA KEPERCAYAAN DIRI DENGAN BULLYING PADA SISWA KELAS VIII SMP PGRI 1 SEMARANG
Authors: Ravi Aji Pratama  , Heri Saptadi Ismanto  , Ismah  
Published: October 2023

ABSTRAK

Ravi aji pratama NPM 19110013.”Hubungan Antara Kepercayaan diri dengan Bullying Pada Siswa Kelas VIII SMP PGRI 1 SEMARANG”. Skripsi program studi Bimbingan dan Konseling Fakultas ilmu pendidikan Universitas PGRI Semarang 2023. Dosen Pembimbing I : Dr. Heri Saptadi Ismanto, S.Pd.,M.Pd.,kons. Pembimbingn II : Ismah,S.Ag.,M.Pd.
Dalam penelitian ini metode yang digunakan adalah metode penelitian kuantitatif dengan desain penelitian korelasional. Populasi dalam penelitian ini berjumlah 256. Sempel dalam penelitian ini mengambil 38% dari jumlah populasi ,sehingga sempel yang digunakan berjumlah 96 siswa, terdiri dari kelas 8a,8b,8c. Teknik pengambilan sampling pada penelitian ini menggunakan teknik Random sempling. Cara penggunaan teknik random sampling ini dengan menggunakan cara sederhana yaitu dengan menggulung lintingan kertas yang sudah diberi kode kelas, lalu peneliti mengocok secara acak, bagi lintingan yang muncul maka itulah yang menjadi subjek penelitian. Dengan kelas yang terpilih sebagai penelitian adalah kelas VIII A, VIII B, dan VIII C.
Pengujian hipotesis menggunakan korelasi product moment diketahui bahwa nilai sig. (2-tailed) diperoleh 0,013 < 0,05 yang berarti terdapat hubungan yang signifikan antara kepercayaan diri dengan perilaku bullying siswa. Diketahui bahwa nilai koefesien korelasi (r) adalah -0,252 dengan tafar negatif. Berdasarkan tabel nilai korelasi (r) -0,252 pada pedoman nilai interpretasi korelasi berada pada rentang “0,20-0,399” yang berarti bahwa tingkat hubungan kepercayaan diri dengan perilaku bullying termasuk pada kategori rendah.
Kemudian besarnya sumbangan variabel kepercayaan diri dan perilaku bullying yang diperoleh sebesar 6,3%. Karena hubungan yang bersifat negatif hal ini berarti semakin tinggi kepercayaan diri yang dimiliki siswa maka semakin rendah untuk mendapatkan perilaku bullying, dan juga sebaliknya jika semakin rendah kepercayaan diri yang dimiliki siswa maka semakin tinggi untuk mendapatkan perilaku bullying. Secara umum penelitian ini dapat mengetahui pentingnya hubungan antara kepercayaan diri dengan bullying pada siswa sehingga dapat menjadi acuan guru bimbingan dan konseling untuk memberikan layanan dalam rangka mengembangkan kepercayaan diri siswa agar siswa sulit untuk mendapatkan prilaku bullying.

Kata Kunci : hubungan antara kepercayaan diri dengan bullying
Characteristics of food products from holothurias during their complex processing
Authors: Kuznecov Yuriy , Slutskaya Tatyana Noevna , Timchishina Galina 
Published: October 2023

The results showing the possibility of complex use of holothurians for obtaining food products, including biologically active additives (BAA) are presented. The possibility of adjusting the amino acid composition of culinary products based on cucumaria by adding components of terrestrial origin is shown. The characteristics of dietary supplements from the muscle tissue of holothurians are given. The conditions for the rational processing of waste from the cutting of trepang and cucumaria using proteolysis are substantiated.
The resulting products contain glycosides, amino sugars, collagen and selenium.
Prevalence of Oral Manifestations of Systemic Diseases in Patients Visiting the Dental Outpatient Department of Sindh, Pakistan
Authors: Sajjad Batool , Masood Sabeen , Aslam Mehmil , Avais Nayha , Khan Gul Hina , Abbas Syed Zafar , Ayub Tahera 
Published: October 2023

OBJECTIVES
The purpose of the study was to evaluate the awareness of oral health workers in identifying the prevalence of oral manifestations of systemic diseases in patients visiting the Dental Out-Patient Department of Sindh, Pakistan.
METHODOLOGY
A descriptive, cross-sectional survey-based study was conducted in Karachi, Pakistan, from October to December 2021. The study was conducted in various institutes from all over Sindh, Pakistan. An online, well-structured questionnaire was designed using Google Forms and distributed to the participants through social media platforms in the dental community. Using the Open-Epi software regarding a parent article, the sample size of this study was calculated. Keeping the confidence interval at 95% and the desired percentile at 50, the total sample size was calculated to be 100. Around 175 questionnaires were given out to the candidates.
RESULTSThe results showed that 81% male and 19% female participated, including 45% postgraduate trainees, 30% house officers, and 25% general dentists. 80% detected 2-3 systemic diseases in a patient, with 75% observing oral manifestations preceding systemic illness diagnosis. The majority favoured treating underlying ailments (75%), and prevalent conditions included hypertension (90%), diabetes (80%), anaemia (75%), and lichen planus (40.7%).
CONCLUSION
Oral health workers play a vital role in the initial and early identification and multidisciplinary medical management of various systemic diseases. A coordinated approach between physicians and dentists in diagnosing and managing these conditions is necessary to achieve optimal clinical outcomes.
Recent Trends Concerning the Issue of ‘Buddhism and Practice’ in Contemporary Japan
Authors: Kigoshi Yasushi 
Published: October 2023

When discussing Buddhism in practice, we should first note that the word practice has a multilayered meaning in Buddhism. For the purposes of this paper, I would like to simplify things considerably, and divide those multiple meanings into two groups. The first involves the training of one’s mind and body. By engaging in such training, the practitioner is said to draw closer to Buddhist enlightenment. This practice takes various forms depending on the time and place, such as observing the precepts or engaging in meditation, and is referred to as ‘benefiting the self’ (jiri 自利). Second, there is the practice that consists of Buddhists’ activities vis-à-vis society. Even Buddhists, whose fundamental orientation is towards leaving the secular world (shusseken 出世間), have engaged in activities in society that have taken a variety of forms. There are records of Śākyamuni having given various pieces of advice to rulers during ancient times. We also find many records of later Buddhists engaging in missionary and charitable activities. This is referred to as ‘benefiting others’ (rita 利他). In particular, Mahayana Buddhism emphasizes the inseparability of ‘benefiting the self’ and ‘benefiting others.’ Although Buddhist practice is traditionally divided into two categories: self-interest and altruism, it would not be true to say, in fact, that "benefiting others" has always been as much of a primary concern as "benefiting the self." Rather, it can be said that concern for others has always been a weakness of Buddhism, overshadowed by concerns with ‘benefiting the self.’ Thus, Mahayana Buddhism's emphasis on the importance of benefiting others, on the contrary, could be said to imply that this was a weakness of the Buddhism at the time of the Mahayana arose. My paper focuses on recent developments surrounding Buddhism and its practice in contemporary Japan, particularly the element of ‘benefiting others.’ The question of how Buddhists should contribute to society has continually and repeatedly appeared from the origins of Mahayana Buddhism to the present. Against this backdrop, an event occurred in Japan in recent years that marked a major turning point in the issue of Buddhist contributions to society. That event is the Great East Japan Earthquake of 2011. In this paper, I consider the issue of ‘benefiting others’ in Buddhism in light of the effects of the tragic earthquake disaster.
Le Saint-Siège dans les dynamiques de la Guerre froide
Authors: Chenaux Philippe 
Published: October 2023

L’article dresse le bilan des travaux sur la diplomatie vaticane dans les débuts de la Guerre froide. Il montre, d’une part, que la position du Saint-Siège dans le conflit Est-Ouest a évolué entre 1947 et 1958 : contraint, dans un premier temps, d’épouser la cause de l’Occident au nom de la défense de la civilisation chrétienne, le Vatican de Pie XII cherche, surtout à partir de 1951-1952, à retrouver une forme d’équidistance entre les deux blocs plus conforme à la politique d’impartialité suivie pendant les deux guerres mondiales. Il souligne, d’autre part, l’existence de lignes stratégiques concurrentes au sein de la Curie : une ligne atlantiste et résolument anticommuniste (celle des cardinaux du Pentagone Vatican) ; une ligne idéaliste ou tendanciellement neutraliste (autour de Mgr Montini, le futur Paul VI) ; une ligne réaliste ou possibiliste (celle de la première section de la secrétairerie d’État).
Trouver la route vers la Chine
Authors: de Rugy Marie 
Published: October 2023

Si la compétition coloniale entre Français et Britanniques pour l’accès au Yunnan à la fin du xix e siècle est bien connue, l’intérêt des missionnaires français pour la route de la Chine l’est moins. Fondé sur les archives des Missions étrangères de Paris, cet article vise à mettre en lumière les motivations de la Société, les tentatives effectuées sur le terrain par Mgr Bigandet, responsable de la mission de Birmanie à partir de 1856, et d’autres après lui, afin de montrer les rapports qui se nouent entre missions, pouvoir local et puissance coloniale.
Guerre hybride dans le domaine maritime : vers une réponse plus offensive
Authors: Muller Alexis 
Published: October 2023

Les activités chinoises en mer de Chine méridionale, les actions iraniennes dans le golfe Persique, les débordements de puissance turcs en Méditerranée orientale et les derniers incidents en mer Baltique présentent les caractéristiques d’une guerre hybride maritime. Face à ces perturbations stratégiques à très haute valeur ajoutée, il est temps pour la Marine française de réfléchir à ces scénarios et à la manière de les contrer de façon plus offensive : « COIN » (contre-insurrection) maritime, « Lawfare » , emploi de l’hybridité à notre avantage… L’hybridation de la menace en mer conduit à réconcilier une marine mahanienne, orientée vers l’affrontement décisif, avec celle proposée par la Jeune École en comptant sur la mise en réseau des unités.
Quel rôle pour l’État face aux enjeux de financement de la Base industrielle et technologique de défense (BITD) ?
Authors: Burin des Roziers Jacqueline 
Published: October 2023

Le contexte stratégique avec la perspective de conflits de haute intensité implique une mutation de notre outil de défense. Ce passage à une « économie de guerre » nécessite des investissements pour faire évoluer nos outils de production ou améliorer notre résilience, constituer des stocks d’approvisionnements, réinternaliser en France certaines activités, maintenir un niveau d’innovation élevé, mais aussi accompagner des prospects export. Cependant, faute principalement d’une image favorable, l’industrie de défense souffre d’une difficulté d’accès aux financements privés. Face à cette situation, l’État « keynésien » doit utiliser les leviers que lui permettent ses différents rôles de client, d’investisseur, de régulateur et de stratège pour favoriser et accompagner les évolutions nécessaires.
La guerre des V.
Authors: Mak Ariane 
Published: October 2023

Le 17 janvier 1941, Victor de Laveleye, speaker belge de la BBC, enjoint ses compatriotes à inscrire en tout lieu, en symbole de défiance à l’occupant, la lettre V : le V de la Victoire, le V de Vrijheid (la liberté) en flamand. Les graffitis du V de la victoire ne tardent pas à proliférer sur les murs des nations européennes occupées, mais également en Grande-Bretagne, où à l’été 1941, la BBC encourage les Britanniques à rejoindre l’« armée des V ». À partir des notes de terrain du collectif d’enquête du Mass-Observation, l’article explore ce cas rare de « graffiti encouragé », politique sans pour autant être subversif – du moins dans la Grande-Bretagne épargnée par l’occupation, comme ne cessent de le rappeler les contemporains.
Modeling Human Respiratory Syncytial Virus (RSV) Infection: Recent Contributions and Future Directions Using the Calf Model of Bovine RSV Disease
Authors: Díaz Fabián E , McGill Jodi L 
Published: October 2023

Abstract
The human orthopneumovirus (human respiratory syncytial virus [RSV]) is a leading cause of respiratory disease in children worldwide and a significant cause of infant mortality in low- and middle-income countries. The natural immune response to the virus has a preponderant role in disease progression, with a rapid neutrophil infiltration and dysbalanced T cell response in the lungs associated with severe disease in infants. The development of preventive interventions against human RSV has been difficult partly due to the need to use animal models that only partially recapitulate the immune response as well as the disease progression seen in human infants. In this brief review, we discuss the contributions of the calf model of RSV infection to understanding immunity to RSV and in developing vaccine and drug candidates, focusing on recent research areas. We propose that the bovine model of RSV infection is a valuable alternative for assessing the translational potential of interventions aimed at the human population.
Infection Dynamics, Pathogenesis, and Immunity to SARS-CoV-2 in Naturally Susceptible Animal Species
Authors: Nooruzzaman Mohammed , Diel Diego G 
Published: October 2023

Abstract
SARS-CoV-2, the causative agent of the COVID-19 pandemic, presents a broad host range. Domestic cats and white-tailed deer (WTD) are particularly susceptible to SARS-CoV-2 with multiple variant strains being associated with infections in these species. The virus replicates in the upper respiratory tract and in associated lymphoid tissues, and it is shed through oral and nasal secretions, which leads to efficient transmission of the virus to contact animals. Robust cell-mediated and humoral immune responses are induced upon infection in domestic cats, which curb the progression of clinical disease and are associated with control of infection. In WTD, high levels of neutralizing Abs are detected early upon infection. In this review, the current understanding of the infection dynamics, pathogenesis, and immune responses to SARS-CoV-2 infection in animals, with special focus on naturally susceptible felids and WTD, are discussed.
Tensor algebras of subproduct systems and noncommutative function theory
Authors: Hartz Michael , Shalit Orr Moshe 
Published: October 2023

AbstractWe revisit tensor algebras of subproduct systems with Hilbert space fibers, resolving some open questions in the case of infinite-dimensional fibers. We characterize when a tensor algebra can be identified as the algebra of uniformly continuous noncommutative functions on a noncommutative homogeneous variety or, equivalently, when it is residually finite-dimensional: this happens precisely when the closed homogeneous ideal associated with the subproduct system satisfies a Nullstellensatz with respect to the algebra of uniformly continuous noncommutative functions on the noncommutative closed unit ball. We show that – in contrast to the finite-dimensional case – in the case of infinite-dimensional fibers, this Nullstellensatz may fail. Finally, we also resolve the isomorphism problem for tensor algebras of subproduct systems: two such tensor algebras are (isometrically) isomorphic if and only if their subproduct systems are isomorphic in an appropriate sense.