bluuebunny/crossref_metadata_2025_split huggingface dataset:
Correlating Buffering Agents' Premier pH with Interface Stability Toward Long‐Term Zn Metal Anodes
Authors: Zhuang Weiman , Chen Qianwen , Wan Jianyong , Hou Zhen , Huang Limin 
Published: February 2024

AbstractAqueous solvents in Zn metal batteries inevitably induces hydrogen evolution reactions (HER) due to fluctuating pH levels in electrolytes, leading to severe side reactions and dendrite growth. To address these challenges, buffering agents have been recently proposed as a solution to maintain constant electrolyte pH values upon cycling. Nonetheless, the critical role of buffering additives’ premier pH in determining interface stability is largely overlooked. Herein, two types of buffering agents, single amphoteric and conjugate acid‐base pairs, are employed to correlate their initial pHs with the interface stability. Based on the observations, the lifetime of Zn metal anodes initially increases and then decreases as the initial pH level goes up from 2.0 to 5.0, with an optimal lifetime at pH 3.3 for both buffering agent categories. This phenomenon lies in ample H+ in low pH and rich OH− in high pH, leading to either severe HER or by‐products passivation layer. The optimized pH allows cells to deliver a high average Coulombic efficiency of 99.61% over 1500 cycles at a large current density of 5 mA cm−2, which is significantly superior to 345 cycles achieved in the pristine electrolyte. Furthermore, this enhanced interface enables stable Zn/activated carbon full batteries over 15 000 cycles.
Biomimetic Multiscale Oriented PVA/NRL Hydrogel Enabled Multistimulus Responsive and Smart Shape Memory Actuator
Authors: Li Zhaohui , Li Zewei , Zhou Shihao , Zhang Jianming , Zong Lu 
Published: February 2024

AbstractShape memory hydrogels provide a worldwide scope for functional soft materials. However, most shape memory hydrogels exhibit poor mechanical properties, leading to low actuation strength, which severely limits their applications in smart biomimetic devices. Herein, a strategy for muscle‐inspired shape memory‐oriented polyvinyl alcohol (PVA)‐natural rubber latex (NRL) hydrogel (OPNH) with multiscale oriented structure is demonstrated. The shape memory function comes from the stretch‐induced crystallization of natural rubber (NR), while PVA forms strong hydrogen bonding interactions with proteins and phospholipids on the surface of NRL particles. Meanwhile, the reconfigurable interactions of PVA and NR produce a multiscale‐oriented structure during stretch‐drying, improving the mechanical and shape memory properties. The resultant OPNH shows excellent interfacial compatibility, exhibiting outstanding mechanical performance (3.2 MPa), high shape fixity (≈80%) and shape recovery ratio (≈92%), high actuation strength (206 kPa), working capacity (105 kJ m−3), extremely short response time (≈2 s), low response temperature (28 °C) and smart thermal responsiveness. It can even maintain muscle‐like working capacity when lifting a load equivalent to 372 times its weight, providing a new class shape memory material for the application in smart biomimetic muscles and multistimulus responsive devices.
Ultra‐high‐performance liquid chromatography method development for the quantification of Molnupiravir and its process‐related impurities using Box‐Behnken experimental design
Authors: Nuli Mohana Vamsi , Bhikshapathi Darna , Garige Anil Kumar , Chandupatla Vijitha , Sunkara Surya Lakshmi , Grover Parul 
Published: February 2024

AbstractMolnupiravir, a promising antiviral agent, has gained significant attention for its potential in treating viral infections, particularly in the context of the coronavirus disease 2019 pandemic. This study aimed to develop and validate an ultra‐high‐performance liquid chromatography (UHPLC) method for the quantification of Molnupiravir and its associated impurities (Imp‐I, Imp‐II, Imp‐III, and Imp‐IV). The method involved a systematic investigation of critical method parameters and their optimization using Quality by Design principles. The percentage of organic modifiers, column temperature, and flow rate were systematically optimized using the Box‐Behnken design. The developed method was assessed for specificity, system suitability, accuracy, precision, linearity, and detection limits. The results demonstrate strong specificity, with the analysis remaining accurate even in the presence of impurities. The developed method exhibits excellent precision, with repeatability and intermediate precision showing relative standard deviation values ranging from 0.78% to 1.14% for impurities and 0.82% to 1.91% for Molnupiravir. Furthermore, the method displays exceptional linearity, covering a wide range of concentrations. The linear regression analysis yields high coefficients of determination (r2, 9993–0.9997), confirming the linearity. The developed UHPLC method is well‐suited for the accurate and reliable analysis of Molnupiravir and its impurities, making it a valuable tool for quality control and pharmaceutical research applications.
Shear behavior of box‐section concrete beams reinforced by FRP bars and FRP stirrups
Authors: Ebrahim Ebrahim A. , Mahmoud Ahmed A. , Salama Mohamed A. , Khater Ahmed N. 
Published: February 2024

AbstractA few research studies are available on the behavior of reinforced concrete (RC) box section beams with fiber‐reinforced polymer bars (FRP) and FRP stirrups. Consequently, the behavior of these beams needs to be investigated. This article studies experimentally, numerically, and analytically the effect of some variables on the behavior of RC box section beams. This article investigates many variables, such as the shear span‐to‐total depth ratio, the flexural FRP reinforcement ratio, and the FRP vertical and horizontal web reinforcement ratio. The experimental program consists of nine simply supported reinforced concrete box section beams. The numerical models using the nonlinear finite element program ANSYS V.15 are carried out. The results are compared to the experimental results using load‐deflection curves, crack patterns, failure loads, and failure modes. The shear capacities based on Egyptian ECP 208‐2019 and ACI 440‐2015 codes are compared to each other and to the experimental results. The findings show an adequate agreement between the experimental, numerical, and analytical results for the range of the studied parameters. The results reveal that increasing the shear span‐to‐depth ratio by 50% decreases the carrying capacity, toughness, and displacement ductility by 2%, 28%, and 12%, respectively. The increase in main FRP reinforcement rebars by 20% increases the carrying capacity and toughness by 59% and 62%, respectively. Increasing vertical FRP stirrups by 79% increases the failure load and toughness by 26% and 15%, respectively, and displacement ductility increases only by 0.8%. The increase in horizontal FRP stirrups by 79% increases the failure load, toughness, and displacement ductility by 33%, 8%, and 4%, respectively. Both Egyptian and American codes are conservative in some cases and unconservative in others, while the numerical results are unconservative.
Primary hyperparathyroidism and concurrent severe hypergastrinemia in a dog
Authors: Freytet Léa , Boot Grégor , Petitpré Arthur , Lamoureux Anaïs 
Published: February 2024

AbstractA 7‐year‐old, neutered, male beagle dog was presented for the investigation of hyporexia, vomiting and polyuria‐polydipsia. Ionised hypercalcaemia secondary to primary hyperparathyroidism was diagnosed. The dog developed a perforated gastric ulcer associated with marked hypergastrinemia. The dog died of cardiopulmonary arrest 6 days after admission. Gastrinoma can be associated with Zollinger–Ellison syndrome, characterised by the presence of peptic ulcers and hypergastrinemia. Concurrent primary hyperparathyroidism and gastrinoma is a typical presentation of multiple endocrine neoplasia type 1 syndrome, a human syndrome that causes the development of several tumours in endocrine glands; but has never been described in dogs. Hypergastrinemia secondary to hypercalcaemia, and unrelated to gastrinoma, has also been described in humans, but not in dogs. This case reports the atypical co‐occurrence of primary hyperparathyroidism and severe hypergastrinemia, which could be a consequence of hypercalcaemia, or be secondary to a concurrent disease such as an undetected gastrinoma.
Degradation of 2, 4‐dichlorophenol by peroxymonosulfate catalyzed by ZnO/ZnMn2O4
Authors: Ruan Xinchao , Wang Huan , Huang Fengyun , Wang Fanye , Yang Xiaojun 
Published: February 2024

AbstractIn this study, a highly efficient peroxymonosulfate (PMS) activator, ZnO/ZnMn2O4, was synthesized using a simple one‐step hydrothermal method. The resulting bimetallic oxide catalyst demonstrated a homogenous and high‐purity composition, showcasing synergistic catalytic activity in activating PMS for degrading 2, 4‐dichlorophenol (2, 4‐DCP) in aqueous solution. This catalytic performance surpassed that of individual ZnO, Mn2O3, and ZnMn2O4 metal materials. Under the optimized conditions, the removal efficiency of 2, 4‐DCP reached approximately 86% within 60 min, and the catalytic ability remained almost constant even after four cycles of recycling. The developed degradation system proved effective in degrading other azo‐dye pollutants. Certain inorganic anions such as HPO4−, HCO3−, and NO3− significantly inhibited the degradation of 2, 4‐DCP, while Cl− and SO42− did not exhibit such interference. Results from electrochemical experiments indicated that the electron transfer ability of ZnO/ZnMn2O4 surpassed that of individual metals, and electron transfer occurred between ZnO/ZnMn2O4 and the oxidant. The primary active radicals responsible for degrading 2, 4‐DCP were identified as SO4•−, OH• and O2•−, generated through the oxidation and reduction of PMS catalyzed by Zn (II) and Mn (III). Furthermore, X‐ray photoelectron spectroscopy (XPS) analysis of the fresh and used catalysts revealed that the exceptional electron transfer ability of ZnO facilitated the valence transfer of Mn (III) and the transfer of electrons to the catalyst's oxygen surface, thus enhancing the catalytic efficiency. The analysis of radicals and intermediates indicates that the two main pathways for degrading 2, 4‐DCP involve hydroxylation and radical attack on its aromatic ring.Practitioner Points

A bimetallic ZnO/ZnMn2O4 catalyst was synthesized and characterized.
ZnO/ZnMn2O4 can synergistically activate PMS to degrade 2, 4‐DCP compared with single metal oxide.
Three primary active radicals, O2•−, •OH, and SO4•−, were generated to promote the degradation.
ZnO promoted electron transfer among the three species of Mn to facilitate oxidizing pollutants.
Hydroxylation and radical attack on the aromatic ring of 2, 4‐DCP are the two degradation pathways.
Lifting of two-mode states in the D1-D5 CFT
Authors: Hughes Marcel R. R. , Mathur Samir D. , Mehta Madhur 
Published: February 2024

Abstract
We consider D1-D5-P states in the untwisted sector of the D1-D5 orbifold CFT where one copy of the seed CFT has been excited by a pair of oscillators, each being either bosonic or fermionic. While such states are BPS at the orbifold point, they will in general ‘lift’ as the theory is deformed towards general values of the couplings. We compute the expectation value of this lift at second order in the deformation parameter for the above mentioned states. We write this lift in terms of a fixed number of nested contour integrals on a given integrand; this integrand depends on the mode numbers of the oscillators in the state. We evaluate these integrals to obtain the explicit value of the lift for various subfamilies of states. At large mode numbers one observes a smooth increase of the lift with the dimension of the state h; this increase appears to follow $$ \textrm{a}\sim \sqrt{h} $$
a
∼

h

behavior similar to that found analytically in earlier computations for other classes of states.
Heavy Wilson quarks and O(a) improvement: nonperturbative results for bg
Authors: Dalla Brida Mattia , Höllwieser Roman , Knechtli Francesco , Korzec Tomasz , Sint Stefan , Sommer Rainer 
Published: February 2024

Abstract
With Wilson quarks, on-shell O(a) improvement of the lattice QCD action is achieved by including the Sheikholeslami-Wohlert term and two further operators of mass dimension 5, which amount to a mass-dependent rescaling of the bare parameters. We here focus on the rescaled bare coupling, $$ {\tilde{g}}_0^2={g}_0^2\left(1+{b}_{\textrm{g}}a{m}_{\textrm{q}}\right) $$

g
~

0
2

=

g
0
2

1
+

b
g

a

m
q

, and the determination of $$ {b}_{\textrm{g}}\left({g}_0^2\right) $$

b
g

g
0
2

which is currently only known to 1-loop order of perturbation theory. We derive suitable improvement conditions in the chiral limit and in a finite space-time volume and evaluate these for different gluonic observables, both with and without the gradient flow. The choice of β-values and the line of constant physics are motivated by the ALPHA collaboration’s decoupling strategy to determine αs(mZ) [1]. However, the improvement conditions and some insight into systematic effects may prove useful in other contexts, too.
SMEFT at NNLO+PS: Vh production
Authors: Gauld Rhorry , Haisch Ulrich , Schnell Luc 
Published: February 2024

Abstract
In the context of the Standard Model effective field theory (SMEFT) the next-to-next-to-leading (NNLO) QCD corrections to the Higgsstrahlungs (Vh) processes in hadronic collisions are calculated and matched to a parton shower (PS). NNLO+PS precision is achieved for the complete sets of SMEFT operators that describe the interactions between the Higgs and two vector bosons and the couplings of the Higgs, a W or a Z boson, and light fermions. A POWHEG-BOX implementation of the computed NNLO SMEFT corrections is provided that allows for a realistic exclusive description of Vh production at the level of hadronic events. This feature makes it an essential tool for future Higgs characterisation studies by the ATLAS and CMS collaborations. Utilising our new Monte Carlo code the numerical impact of NNLO+PS corrections on the kinematic distributions in pp → Zh → ℓ+ℓ−h production is explored, employing well-motivated SMEFT benchmark scenarios.
Two-point sum-rules in three-dimensional Yang-Mills theory
Authors: Caron-Huot Simon , Pokraka Andrzej , Zahraee Zahra 
Published: February 2024

Abstract
We compute the stress-tensor two-point function in three-dimensional Yang-Mills theory to three-loops in perturbation theory. Using its calculable shape at high momenta, we test the notion that its Borel transform is saturated at low energies by the lowest glueball state(s). This assumption provides relatively stable estimates for the mass of the lightest glueball that we compare with lattice simulations. We also provide estimates for the coupling of the lightest glueball to the stress tensor. Along the way, we comment on the extent that such estimates are non-rigorous. Lastly, we discuss the possibility of applying the sum-rule analysis to two-point functions of higher-spin operators and obtain a crude approximation for the glueball couplings to these operators.
Two Rigidity Results for Stable Minimal Hypersurfaces
Authors: Catino Giovanni , Mastrolia Paolo , Roncoroni Alberto 
Published: February 2024

AbstractThe aim of this paper is to prove two results concerning the rigidity of complete, immersed, orientable, stable minimal hypersurfaces: we show that they are hyperplane in R4, while they do not exist in positively curved closed Riemannian (n+1)-manifold when n≤5; in particular, there are no stable minimal hypersurfaces in Sn+1 when n≤5. The first result was recently proved also by Chodosh and Li, and the second is a consequence of a more general result concerning minimal surfaces with finite index. Both theorems rely on a conformal method, inspired by a classical work of Fischer-Colbrie.
Cloud based manufacturing: A review of recent developments in architectures, technologies, infrastructures, platforms and associated challenges
Authors: Gharibvand Vahid , Kolamroudi Mohammad Karimzadeh , Zeeshan Qasim , Çınar Zeki Murat , Sahmani Saeid , Asmael Mohammed , Safaei Babak 
Published: February 2024

AbstractService-provider industries have used cloud-based technologies in recent years. Information technology (IT) led the development of electronic hardware and software technologies to enable cloud computing as a new paradigm. Other vanguard industries such as communications and financial services leveraged cloud computing technology to develop cloud-based platforms for their respective industries. Manufacturing industry is a relative newcomer to cloud technologies although it has used modern technologies on factory floor to boost production efficiency. Cloud manufacturing (CMfg) is one of the key technologies of Industry 4.0 (I 4.0) and the goal of CMfg is to develop cloud-based approaches in manufacturing that provide flexibility, adaptability, and agility also, reduces challenges caused by system complexity. In recent years, researchers evaluated cloud technologies and proposed initial solutions tailored to manufacturing requirements. However, there are challenges in implementing CMfg due to complexity of technologies, different types of products and wide range of requirements from mass production of consumer products to low-volume specialty products. This paper presents the advantages, challenges and shortcomings associated with applications of the latest technologies to drive transition to CMfg. This research examined cloud technologies proposed for implementation of CMfg such as architectures, models, frameworks, infrastructure, interoperability, virtualization, optimal service selection, etc. This research also studied the role of technologies such as the internet of things (IoT), cyber physical systems (CPS) robotics, big data, radio frequency identification (RFID), 3D printing and artificial intelligence (AI) in accelerating the adoption and future direction of CMfg.
Slowly recurrent Collet–Eckmann maps on the Riemann sphere
Authors: Aspenberg Magnus 
Published: February 2024

AbstractIn this paper we study perturbations of rational Collet–Eckmann maps for which the Julia set is the whole sphere, and for which the critical set is allowed to be slowly recurrent. Generically, if each critical point is simple, we show that each such Collet–Eckmann map is a Lebesgue point of Collet–Eckmann maps in the space of rational maps of the same degree $$d \ge 2$$

d
≥
2

. The same result holds in each subspace, where we fix the multiplicities of the critical points.
In vivo validation of the functional role of MicroRNA-4638-3p in breast cancer bone metastasis
Authors: Akshaya R. L. , Saranya I. , Salomi G. Margaret , Shanthi P. , Ilangovan R. , Venkataraman P. , Selvamurugan N. 
Published: February 2024

Abstract
Purpose
Skeletal metastases are increasingly reported in metastatic triple-negative breast cancer (BC) patients. We previously reported that TGF-β1 sustains activating transcription factor 3(ATF3) expression and is required for cell proliferation, invasion, and bone metastasis genes. Increasing studies suggest the critical regulatory function of microRNAs (miRNAs) in governing BC pathogenesis. TGF-β1 downregulated the expression of miR-4638-3p, which targets ATF3 in human BC cells (MDA-MB-231). In the present study, we aimed to identify the functional role of miR-4638-3p in BC bone metastasis by the caudal artery injection of the MDA-MB-231 cells overexpressing mir-4638 in the mice.

Methods
MDA-MB-231 cells overexpressing miR-4638 were prepared by stable transfections. Reverse transcriptase quantitative PCR was carried out to determine the expression of endogenous miR-4638-3p and bone resorption marker genes. X-ray, micro-CT, and Hematoxylin & Eosin studies were used to determine osteolytic lesions, trabecular structure, bone mineral density, and micrometastasis of cells.

Results
The mice injected with MDA-MB-231 cells overexpressing miR-4638-3p decreased the expression of bone resorption marker genes, compared to MDA-MB-231 cells injection. Reduced osteolytic lesions and restored bone density by MDA-MB-231 cells overexpressing miR-4638-3p were observed. Similarly, the mice injected with MDA-MB-231 cells overexpressing miR-4638-3p showed a better microarchitecture of the trabecular network. A few abnormal cells seen in the femur of MDA-MB-231 cells-injected mice were not found in MDA-MB-231 cells overexpressing miR-4638.

Conclusion
The identified functional role of ATF3 targeting miR-4638-3p in BC bone metastasis in vivo suggests its candidature as BC therapeutics in the future.
OpenWorkFlow—Development of an open-source synthesis-platform for safety investigations in the site selection process
Authors: Lehmann Christoph , Bilke Lars , Buchwald Jörg , Graebling Nico , Grunwald Norbert , Heinze Julian , Meisel Tobias , Lu Renchao , Naumov Dmitri , Rink Karsten , Özgür Sen Ozan , Selzer Philipp , Shao Haibing , Wang Wenqing , Zill Florian , Nagel Thomas , Kolditz Olaf 
Published: February 2024

AbstractThe identification of appropriate locations for secure nuclear waste disposal, a crucial aspect of Germany’s nuclear phase-out strategy (StandAG 2017), remains a significant scientific, technical, and political challenge worldwide. The selection and safety assessment of sites demand extensive applications of numerical methods. The OpenWorkFlow project, initiated by Bundesgesellschaft für Endlagerung (BGE), develops a new, open synthesis platform to virtualise repository systems. The simulation platform will evaluate far-field and near-field processes, supporting the site selection process first and the geotechnical design of repository systems later on. The project’s development philosophy adheres to the principles of continuity and innovation. Through continuous scientific development, the OpenWorkFlow platform will remain at the forefront of science and technology. Furthermore, as a digital platform, OpenWorkFlow employs up-to-date IT methods and constantly evolving software concepts. As its name suggests, OpenWorkFlow (OWF) is an open platform, developed on the basis of FAIR principles as an open-source project, inviting community participation.This paper primarily focuses on the technical aspects of OWF, with only a brief discussion of conceptual principles and modelling methods. In the second part of the manuscript, demonstration examples from different scales are presented to illustrate the current technical status of OWF and to emphasize the requirement for further development.
The Dubousset Functional Test: a reliable and valid test in early stage Parkinson’s disease patients
Authors: Abit Kocaman Ayşe , Aydoğan Arslan Saniye , Bozkurt Yusuf Emre , Coşkun Erdal 
Published: February 2024

Abstract
Introduction
Dubousset Functional Test (DFT) is an assessment test evaluating the functional capacity and dynamic balance. The study aimed to examine the reliability, validity, and responsiveness of the DFT in early stage Parkinson’s disease (PD) patients.

Methods
This was a cross-sectional study. Thirty-three early stage PD patients were recruited. The DFT was performed along with the Timed Up and Go (TUG) test, dual-task TUG, Functional Reach Test (FRT), 3-m backward walk test (3MBWT), Tinetti Performance-Oriented Mobility Assessment (POMA), and Berg Balance Scale (BBS).

Results
The test–retest reliability of the subcomponents of the DFT was excellent. The ICCs were as follows: 0.952, 0.955, 0.917, and 0.919, respectively. The correlation with subcomponents of DFT and TUG, dual-task TUG, FRT, 3MBWT, BBS, and POMA was found to be statistically significant (p < 0.05). The standard measurement errors of the subcomponents of the DFT were 1.45, 1.39, 1.70, and 1.57, respectively. The minimal clinically important difference (MCID) of the subcomponents was 2.05, 1.97, 2.41, and 2.22, respectively.

Conclusion
The DFT is a reliable, valid, and easy-to-administer tool in assessing the balance and physical function of early stage PD patients.