bluuebunny/crossref_metadata_2025_split huggingface dataset:
Habitat heterogeneity reduces abundance of invasive mealybugs in subtropical fruit crops
Authors: Plata Ángel , Tena Alejandro , Beitia Francisco José , Sousa José Paulo , Paredes Daniel 
Published: January 2024

Abstract

The simplification of agricultural landscapes has been associated with an increase in pest pressure. While monocultures increase the resources available for pests and may facilitate their dispersion, the lack of non‐crop habitats may reduce the resources available for pest natural enemies. Herein, we tested which of these hypotheses, namely ‘resource concentration’ and ‘natural enemies’, can better explain the abundance of invasive mealybug pests in two subtropical fruit crops.

For this aim, 17 persimmon orchards and 16 citrus orchards were sampled during three different seasons across two consecutive years. Using a model selection approach, we assessed the effects of the surrounding landscape (proportion of focal crops and semi‐natural habitats at different distances) and inter‐row ground cover vegetation on the abundance of mealybugs and their natural enemies.

The proportion of focal crop in the landscape increased the abundance of mealybugs attacking both crops. This effect was found at closer distances (up to ~600 m) in citrus and at both closer and further distances (up to 1250 m) in persimmon.

Non‐crop habitats, both surrounding semi‐natural habitats and ground cover vegetation, decreased the abundance of mealybugs by increasing the activity of their parasitoids in persimmon. Conversely, non‐crop habitats did not decrease the abundance of the main mealybug species attacking citrus, likely because this mealybug species was not attacked by native or naturalized parasitoids.

Synthesis and applications. Our models show that the increase in habitat heterogeneity at local and landscape scales can reduce the abundance of invasive mealybugs in subtropical crops via ‘resource concentration’ and ‘natural enemies’ mechanisms. Therefore, habitat diversification strategies should be considered in the conservation biological control of invasive mealybugs. Importantly, our findings also show that the presence of efficient natural enemies is critical to maximize their control through habitat diversification strategies.
Metagenomic and proteomic insights into the self‐adaptive cell surface hydrophobicity of Sphingomonas sp. strain PAH02 reducing the migration of cadmium‐phenanthrene co‐pollutant in rice
Authors: Yi Shengwei , Zhu Zhongnan , Li Feng , Zhu Lizhong , Wu Chen , Ge Fei , Ji Xionghui , Tian Jiang 
Published: January 2024

AbstractCell surface hydrophobicity (CSH) dominates the interactions between rhizobacteria and pollutants at the soil‐water interface, which is critical for understanding the dissipation of pollutants in the rhizosphere microzone of rice. Herein, we explored the effects of self‐adaptive CSH of Sphingomonas sp. strain PAH02 on the translocation and biotransformation behaviour of cadmium‐phenanthrene (Cd‐Phe) co‐pollutant in rice and rhizosphere microbiome. We evidenced that strain PAH02 reduced the adsorption of Cd‐Phe co‐pollutant on the rice root surface while enhancing the degradation of Phe and adsorption of Cd via its self‐adaptive CSH in the hydroponic experiment. The significant upregulation of key protein expression levels such as MerR, ARHDs and enoyl‐CoA hydratase/isomerase, ensures self‐adaptive CSH to cope with the stress of Cd‐Phe co‐pollutant. Consistently, the bioaugmentation of strain PAH02 promoted the formation of core microbiota in the rhizosphere soil of rice (Oryza sativa L.), such as Bradyrhizobium and Streptomyces and induced gene enrichment of CusA and PobA that are strongly associated with pollutant transformation. Consequently, the contents of Cd and Phe in rice grains at maturity decreased by 17.2% ± 0.2% and 65.7% ± 0.3%, respectively, after the bioaugmentation of strain PAH02. These findings present new opportunities for the implementation of rhizosphere bioremediation strategies of co‐contaminants in paddy fields.
Fallen fruit: A backup resource during winter shaping fruit fly communities
Authors: Deconninck Gwenaëlle , Boulembert Méghan , Eslin Patrice , Couty Aude , Dubois Françoise , Gallet‐Moron Emilie , Pincebourde Sylvain , Chabrerie Olivier 
Published: January 2024

Abstract
Fallen fruits provide important feeding and breeding substrates for insects such as Drosophilidae and can be a potential trophic reservoir when usual host fruits become scarce.
Recently, two invasive fruit fly species, Drosophila suzukii and Chymomyza amoena, have become established in Europe and are expected to alter existing Drosophilidae communities.
In this study, carried out between September 2021 and April 2022 in northern France, we aimed to disentangle the relative roles of microclimatic, landscape and local factors driving the diversity of the Drosophilidae community in decaying fruit across seasons.
Minimum site temperature during the week preceding sampling and the proportion of rotten fruit tissue had the strongest positive influence on Drosophilidae abundance and species richness. Drosophilidae abundance also increased with urbanisation (portion of building cover) around the sampled trees.
Decaying apples were important breeding sites for C. amoena across seasons, but provided a suboptimal substrate for D. suzukii, which was only present in late summer.
This study sheds light on the important role of unharvested fallen crop fruit in maintaining the diversity of an insect family that is generally overlooked in field studies. It also emphasises the importance of considering multiple scales and factors when studying the interactions between invasive species, native species and their shared trophic resources. Finally, our data highlight the importance of the Drosophilidae community in recycling agricultural waste.
The habits of European urologists in the field of cryopreservation before the urological cancers treatment
Authors: Degraeve Amandine , Roumeguere Thierry , Tilmans Gilles , Marotta Marie‐Laura , Huyghe Eric , Fournier Georges , Faix Antoine , Spinoit Anne‐Françoise , Decaestecker Karel , Herve François , Boitrelle Florence , Lahdensuo Kanerva , Tosco Lorenzo , Van Damme Julien ,   the Société Belge d'Urologie (SBU), the Belgische Vereniging voor Urologen (BVU), the Association Française d'Urologie (AFU), The Nederlandse Vereniging voor Urologie (NVU), the Société d'Andrologie de Langue Française (SALF), the Finnish Urological Society (FUS)
Published: January 2024

AbstractIntroductionTreatments against urogenital cancers frequently have fertility side‐effects. The strategy to preserve fertility after oncologic treatments is still a matter of debate with a lack of evidence and international guidelines. The aim of this study is to investigate fertility preservation practices before urogenital cancer treatments and to compare national habits.Material and methodsAn online anonymous survey was submitted from January to June 2021 to six European urological societies. The 31‐items questionnaire included questions about demography, habits of evaluation, and management of fertility preservation in case of urogenital cancer treatments.ResultsTwo hundred twenty‐eight urologists from six urological societies in five different countries (Belgium, The Netherlands, Luxembourg, France, Finland) filled out the survey.Three quarter (74%; n = 166) usually propose a cryopreservation before orchidectomy. In case of oligo/azoo‐spermia, the technique performed for the sperm extraction during orchidectomy varies among the sample: 70.5% (n = 160) of the responders do not perform a Testicular Sperm Extraction (TESE) nor a Percutaneous Epididymal Sperm Aspiration (PESA).The cryopreservation for prostate cancer treatments is never proposed in 48.17% (n = 105) of responders but conversely it is always proposed in 5.05% (n = 11).The cryopreservation before bladder cancer treatments is not commonly proposed (67.5%, n = 154).ConclusionOur study showed variable country specific tendencies in terms of fertility preservation in the period of treatment of urological cancers. These differences seem to be related to national guidelines recommendations. Standardization of international guidelines is urgently needed in the field of fertility for urological cancer patients.
Birth asphyxia and its association with grand multiparity and referral among hospital births: A prospective cross‐sectional study in Benin, Malawi, Tanzania and Uganda
Authors: Handing Greta , Straneo Manuela , Agossou Christian , Wanduru Phillip , Kandeya Bianca , Abeid Muzdalifat S. , Annerstedt Kristi S. , Hanson Claudia 
Published: January 2024

AbstractIntroductionBirth asphyxia is a leading cause of neonatal mortality in sub‐Saharan Africa. The relationship to grand multiparity (GM), a controversial pregnancy risk factor, remains largely unexplored, especially in the context of large multinational studies. We investigated birth asphyxia and its association with GM and referral in Benin, Malawi, Tanzania and Uganda.Material and methodsThis was a prospective cross‐sectional study. Data were collected using a perinatal e‐Registry in 16 hospitals (four per country). The study population consisted of 80 663 babies (>1000 g, >28 weeks’ gestational age) delivered between July 2021 and December 2022. The primary outcome was birth asphyxia, defined by 5‐minute appearance, pulse, grimace, activity and respiration score <7. A multilevel and stratified multivariate logistic regression was performed with GM (parity ≥5) as exposure, and birth asphyxia as outcome. An interaction between referral (none, prepartum, intrapartum) and GM was also evaluated as a secondary outcome. All models were adjusted for confounders. Clinical Trial: Pan African Clinical Trial Registry 202006793783148.ResultsBirth asphyxia was present in 7.0% (n = 5612) of babies. More babies with birth asphyxia were born to grand multiparous women (11.9%) than to other parity groups (≤7.6%). Among the 76 850 cases included in the analysis, grand multiparous women had a 1.34 times higher odds of birth asphyxia (95% confidence interval [CI] 1.17–1.54) vs para one to two. Grand multiparous women referred intrapartum had the highest probability of asphyxiation (13.02%, 95% CI 9.34–16.69). GM increased odds of birth asphyxia in Benin (odds ratio [OR] 1.37, 95% CI 1.13–1.68) and Uganda (OR 1.29, 95% CI 1.02–1.64), but was non‐significant in Tanzania (OR 1.44, 95% CI 0.81–2.56) and Malawi (OR 0.98, 95% CI 0.67–1.44).ConclusionsThere is some evidence of an increased risk of birth asphyxia for grand multiparous women having babies at hospitals, especially following intrapartum referral. Antenatal counseling should recognize grand multiparity as higher risk and advise appropriate childbirth facilities. Findings in Malawi suggest an advantage of health systems configuration requiring further exploration.
Gynecological cancer during pregnancy—From a gyne‐oncological perspective
Authors: Bohlin Katja Stenström , Brännström Mats , Dahm‐Kähler Pernilla 
Published: January 2024

AbstractGynecological cancer diagnosed during pregnancy requires accurate diagnosis and staging to determine optimal treatment based on gestational age. Cervical and ovarian cancers are the most common and multidisciplinary team collaboration is pivotal. Magnetic resonance imaging and ultrasound can be used without causing fetal harm. In cervical cancer, early‐stage treatments can often be delayed until fetal lung maturation and cesarean section is recommended if disease prevails, in combination with a simple/radical hysterectomy and lymphadenectomy. Chemoradiotherapy, the recommended treatment for advanced stages, is not compatible with pregnancy preservation. Most gestational ovarian cancers are diagnosed at an early stage and consist of nonepithelial cancers or borderline tumors. Removal of the affected adnexa during pregnancy is often necessary for diagnosis, though staging can be performed after delivery. In selected cases of advanced cervical and ovarian cancers, neoadjuvant chemotherapy may be an option to allow gestational advancement but only after thorough multidisciplinary discussions and counseling.
Thalidomide suppresses migration and invasion of colorectal cancer cells by inhibiting HOXB7‐mediated activation of the Wnt/β‐catenin signaling pathway
Authors: Liu Liyang , Xue Wusong 
Published: January 2024

AbstractHeaps of studies have verified the effects of thalidomide (THA) on colorectal cancer (CRC). Howbeit, the corresponding mechanism awaits illustration, which is the foothold of this study. Following the treatment of 0, 1.94, 7.75, or 19.36 μM THA, CRC cell viability, apoptosis, migration, and invasion were evaluated by methyl tetrazolium, flow cytometry, wound‐healing, and transwell assays. Homeobox B7 (HOXB7) expression in CRC was analyzed and detected by bioinformatics analysis, quantitative real‐time PCR or western blot. After the corresponding transfection or treatment with inhibitor of catenin‐responsive transcription‐3 (iCRT‐3), abovementioned CRC cell biological behaviors as well as expression levels of HOXB7 and β‐catenin were evaluated. 7.75 and 19.36 μM THA dwindled CRC cell viability, migration, and invasion, and facilitated apoptosis. HOXB7 upregulation was detected in CRC cells, which promoted the viability, migration, invasion, and β‐catenin expression, and weakened the apoptosis of CRC cells. Also, HOXB7 upregulation counteracted the effects of THA on CRC cells. iCRT‐3 restrained β‐catenin expression, viability, migration, and invasion, whereas promoting the apoptosis of CRC cells. In addition, iCRT‐3 antagonized the effects of overexpressed HOXB7 on CRC cells. THA inhibits the migration and invasion of CRC cells, which is achieved by suppressing HOXB7‐mediated activation of Wnt/β‐catenin signaling pathway.
Easy assessment of the avidity of polyclonal allergen‐specific serum antibodies
Authors: Strobl Maria R. , Demir Hilal , Wozniak‐Knopp Gordana , Wangorsch Andrea , Rüker Florian , Bohle Barbara 
Published: January 2024

AbstractIntroductionAllergen‐specific IgE‐blocking IgG antibodies contribute to successful allergen immunotherapy (AIT), however, not much is known about their affinity. Since affinity measurements of polyclonal antibodies in serum are technically challenging we evaluated the applicability of acidic disruption of antibody‐allergen complexes by a modified ELISA protocol with monoclonal antibodies (mAbs) specific for the relevant major allergens Betv1 and Mald1. Then, AIT‐induced blocking and non‐blocking Mald1‐specific antibodies in sera from individuals with or without reduced apple allergy were compared.MethodsAfter testing their pH stability coated recombinant allergens were incubated with (i) mAbs diluted in PBS or human serum and (ii) sera from individuals after sublingual administration of Mald1 or Betv1 for 16 weeks. Immune complexes were exposed to buffers in the pH range of 6.4–3.4 and residual antibodies were measured. Avidity indexes (AI), defined as the pH removing 50% of antibodies, were compared to the dissociation constants (KD) of mAbs determined by surface plasmon resonance.ResultsThe selected pH range was applicable to disrupt allergen complexes with highly affine mAbs without compromising allergen integrity. AIs of mAbs accorded with KD values and were unaffected by epitope specificity or the presence of serum proteins. The inter‐assay variability was <4% CV. Protective Mald1‐specific IgG antibodies from individuals with reduced apple allergy showed a higher collective binding strength than that of the non‐protective antibodies of individuals without reduced apple allergy.ConclusionAcidic disruption of allergen‐antibody complexes may be used to estimate the net‐binding force of polyclonal serum antibodies and eases the investigation of affinity‐related research questions in AIT.
Featured Cover
Authors: Ezz Mohamed Aboul , Takahashi Masashi , Rivera Rocío Melissa , Balboula Ahmed Zaky 
Published: January 2024

The cover image is based on the Original Article Cathepsin L regulates oocyte meiosis and preimplantation embryo development by Mohamed Aboul Ezz et al., https://doi.org/10.1111/cpr.13526.
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Trends in underlying causes of death in allogeneic hematopoietic cell transplant recipients over the last decade
Authors: Søborg Andreas , Reekie Joanne , Sengeløv Henrik , Da Cunha‐Bang Caspar , Lund Thomas Kromann , Ekenberg Christina , Lodding Isabelle Paula , Moestrup Kasper Sommerlund , Lundgren Louise , Lundgren Jens D. , Wareham Neval Ete 
Published: January 2024

AbstractObjectivesImproved survival after hematopoietic cell transplantation (HCT) and an increasingly comorbid transplant population may give rise to new trends in the causes of death.MethodsThis study includes all adult allogeneic HCT recipients transplanted at Rigshospitalet between January 1, 2010 and December 31, 2019. Underlying causes of death were determined using the Classification of Death Causes after Transplantation (CLASS) method.ResultsAmong 802 HCT recipients, 289 died during the study period. The main causes of death were relapse (N = 133, 46.0%), graft‐versus‐host disease (GvHD) (N = 64, 22.1%) and infections (N = 35, 12.1%). Multivariable analyses showed that with increasing transplant calendar year, a decreased risk of all‐cause mortality (HR 0.92, 95% CI 0.87–0.97) and death from GvHD (HR 0.87, 95% CI 0.78–0.97) was identified, but not for other specific causes.Standardized mortality ratios (SMRs) for all‐cause mortality decreased from 23.8 (95% CI 19.1–28.5) to 18.4 (95% CI 15.0–21.9) for patients transplanted in 2010–2014 versus 2015–2019, while SMR for patients who died from GvHD decreased from 8.19 (95% CI 5.43–10.94) to 3.65 (95% CI 2.13–5.18).ConclusionsAs risk of all‐cause mortality and death from GvHD decreases, death from relapse remains the greatest obstacle in further improvement of survival after HCT.
Exploring the interplay of attitudes: The transfer of self‐efficacy and emotions between L1 Chinese and L2 English integrated writing contexts
Authors: Zhu Siyu , Yao Yuan , Zhu Xinhua 
Published: January 2024

AbstractIn today's multilingual society, students often learn two or more languages simultaneously. Despite a wealth of research on writing attitudes, few studies have explored the relationship between student attitudinal variables from a cross‐linguistic perspective, particularly in the field of integrated writing (IW). This study included 239 first‐year English majors from a normal university in southeastern China. Path analysis revealed clear relationships between cognitive and affective attitudes, with self‐efficacy being a significant negative predictor of anxiety (β = −0.391 for L1 and β = −0.258 for L2) and a positive predictor of enjoyment (β = 0.531 for L1 and β = 0.380 for L2), irrespective of the language. The study identified statistical evidence of transfers from L1 attitudes to L2 attitudes, across cognitive and affective attitudes, with various patterns. The study provides a cross‐linguistic perspective on the relationship between L1 Chinese and L2 English IW attitudes in Chinese higher education and highlights the critical contribution of psychological transfer in compensating for the limitations of previous theories and empirical studies that focused solely on linguistic ability and writing strategy transfer.
Reduced human leukocyte antigen mismatching is associated with more favourable outcomes after unrelated donor haematopoietic stem cell transplantation
Authors: Valatkaite‐Rakstiene Beatrice , Cekauskiene Rita , Zvirblis Tadas , Jakubauskas Arturas 
Published: January 2024

AbstractThe patient–donor human leukocyte antigen (HLA) match remains the most important prognostic factor for successful unrelated donor haematopoietic stem cell transplantation (UD‐HSCT). This single‐centre study comprised 125 adult patients with malignant haematological diseases undergoing their first UD‐HSCT. The primary goal of this study was to validate the impact of HLA matching on HSCT outcomes, specifically at the HLA‐DPB1 and HLA‐DRB3/4/5 loci. A multivariable Cox regression analysis with a backward selection algorithm was employed to assess the associations of selected prognostic factors with outcomes after UD‐HSCT. Any HLA locus mismatch was found to be associated with an increased incidence of grade II–IV acute graft versus host disease (aGvHD) at 100 days (p = .031; hazard ratio [HR] 1.935) and 6 months (p = .004; HR 2.284) after HSCT. The results of the following analyses also confirmed the strong impact of HLA‐DPB1‐only mismatch on the incidence of grade II–IV aGvHD at 100‐day (p = .006; HR 2.642) as well as at 6‐month (p = .007; HR 2.401) time periods. The HLA‐DPB1‐only mismatch was also shown to be statistically significantly associated with lower relapse incidence (p = .034; HR 0.333). The impact of the HLA‐DRB3/4/5 mismatch on outcomes was inconclusive, though the two and more HLA‐DPB1 + DRB3/4/5‐only mismatches showed a trend towards worse outcomes than a single mismatch. Based on our findings and those of more comprehensive studies, the extended HLA loci typing of patients and donors is suggested to avoid unexpected HLA mismatches during the UD selection.
The role of local meaning in infants' fixations of natural scenes
Authors: Oakes Lisa M. , Hayes Taylor R. , Klotz Shannon M. , Pomaranski Katherine I. , Henderson John M. 
Published: January 2024

AbstractAs infants view visual scenes every day, they must shift their eye gaze and visual attention from location to location, sampling information to process and learn. Like adults, infants' gaze when viewing natural scenes (i.e., photographs of everyday scenes) is influenced by the physical features of the scene image and a general bias to look more centrally in a scene. However, it is unknown how infants' gaze while viewing such scenes is influenced by the semantic content of the scenes. Here, we tested the relative influence of local meaning, controlling for physical salience and center bias, on the eye gaze of 4‐ to 12‐month‐old infants (N = 92) as they viewed natural scenes. Overall, infants were more likely to fixate scene regions rated as higher in meaning, indicating that, like adults, the semantic content, or local meaning, of scenes influences where they look. More importantly, the effect of meaning on infant attention increased with age, providing the first evidence for an age‐related increase in the impact of local meaning on infants' eye movements while viewing natural scenes.
Clinicians' power in the inpatient care of anorexia nervosa: A qualitative investigation of consumer perspectives
Authors: Zugai Joel Sebastian , Gill Katherine , Ramjan Lucie 
Published: January 2024

AbstractMedically compromised people with anorexia nervosa are cared for in inpatient settings where clinicians closely monitor health and safety. Clinicians are in a position of power, with the capacity to impose mandated weight gain to achieve medical stabilisation. Consumers are in a vulnerable position, compelled to temporarily relinquish autonomy and to accept coercive practices that often diminish the quality of the therapeutic relationship. Clinicians' position of power in mental healthcare has a dual potential for both healing and harm, and limited attention has been given to consumers' views of clinicians' power. The aim of this qualitative descriptive study was to investigate the consumer perspective of clinicians' power in the inpatient care of anorexia nervosa, establishing insight into the beneficence and maleficence of the power asymmetry. Ten women with anorexia nervosa in the community participated in semi‐structured interviews online. The COREQ checklist was used to ensure accuracy and completeness of reporting. Thematic analysis revealed that abuses of power were common in the course of inpatient AN care, however life‐saving measures were regarded as defensible. The perception of clinicians' power was determined by the strength of interpersonal relationships and clinicians' clinical competence. To mitigate the potential for harmful experiences, clinicians' use of power must be exercised with close consideration for consumer perspectives, with the integration of person‐centred care and trauma‐informed care principles.