bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sedentary behavior does not predict low BMD nor fracture—population-based Canadian Multicentre Osteoporosis Study
Authors: Guðmundsdóttir Sigríður Lára , Berger Claudie , Macdonald Heather , Adachi Jonathan D , Hopman Wilma M , Kaiser Stephanie M , Kovacs Christopher S , Davison Kenneth Shawn , Morin Suzanne N , Goltzman David ,   CaMos Research Group, Goltzman David , Kreiger Nancy , Tenenhouse Alan , Rahme Elham , Brent Richards J , Morin Suzanne N , Berger Claudie , Joyce Carol , Kovacs Christopher S , Kirkland Susan , Kaiser Stephanie M , Brown Jacques P , Bessette Louis , Anastassiades Tassos P , Towheed Tanveer , Hopman Wilma M , Cheung Angela M , Josse Robert G , Kin On Wong Andy , Adachi Jonathan D , Papaioannou Alexandra , Olszynski Wojciech P , Shawn Davison K , Hanley David A , Boyd Steven K , Prior Jerilynn C , Kalyan Shirin , Lentle Brian , Patel Millan S , Jackson Stuart D , Leslie William D , Prior Jerilynn C 
Published: January 2024

Abstract
Sedentary behavior (SB) or sitting is associated with multiple unfavorable health outcomes. Bone tissue responds to imposed gravitational and muscular strain with there being some evidence suggesting a causal link between SB and poor bone health. However, there are no population-based data on the longitudinal relationship between SB, bone change, and incidence of fragility fractures. This study aimed to examine the associations of sitting/SB (defined as daily sitting time), areal BMD (by DXA), and incident low trauma (fragility) osteoporotic fractures (excluding hands, feet, face, and head). We measured baseline (1995-7) and 10-yr self-reported SB, femoral neck (FN), total hip (TH), and lumbar spine (L1–L4) BMD in 5708 women and 2564 men aged 25 to 80+ yr from the population-based, nationwide, 9-center Canadian Multicentre Osteoporosis Study. Incident 10-yr fragility fracture data were obtained from 4624 participants; &gt;80% of fractures were objectively confirmed by medical records or radiology reports. Vertebral fractures were confirmed by qualitative morphological methods. All analyses were stratified by sex. Multivariable regression models assessed SB-BMD relationships; Cox proportional models were fit for fracture risk. Models were adjusted for age, height, BMI, physical activity, and sex-specific covariates. Women in third/fourth quartiles had lower adjusted FN BMD versus women with the least SB (first quartile); women in the SB third quartile had lower adjusted TH BMD. Men in the SB third quartile had lower adjusted FN BMD than those in SB first quartile. Neither baseline nor stable 10-yr SB was related to BMD change nor to incident fragility fractures. Increased sitting (SB) in this large, population-based cohort was associated with lower baseline FN BMD. Stable SB was not associated with 10-yr BMD loss nor increased fragility fracture. In conclusion, habitual adult SB was not associated with subsequent loss of BMD nor increased risk of fracture.
First-line nivolumab plus ipilimumab with or without chemotherapy for Japanese patients with non-small cell lung cancer: LIGHT-NING study
Authors: Imai Hisao , Kijima Takashi , Azuma Koichi , Kishi Kazuma , Saito Haruhiro , Yamaguchi Teppei , Tanizaki Junko , Yoneshima Yasuto , Fujita Kohei , Watanabe Satoshi , Kitazono Satoru , Fukuhara Tatsuro , Hataji Osamu , Toi Yukihiro , Mizutani Hideaki , Hamakawa Yusuke , Maemondo Makoto , Ohsugi Tomoyuki , Suzuki Keisuke , Horinouchi Hidehito , Ohe Yuichiro 
Published: January 2024

Abstract

Objective
As first-line treatment for stage IV or recurrent non-small cell lung cancer, combination immunotherapy with nivolumab and ipilimumab, with or without chemotherapy, had demonstrated survival benefits over chemotherapy; however, data on Japanese patients are limited.

Methods
LIGHT-NING was a multicenter, observational study and retrospectively collected data. In this interim analysis, we analyzed patients who received combination immunotherapy between 27 November 2020 and 31 August 2021 for the treatment status, safety objectives (treatment-related adverse events and immune-related adverse events incidences), and effectiveness objectives (objective response rate and progression-free survival) to determine the characteristics and early safety information.

Results
We analyzed 353 patients, with a median follow-up of 7.1 (interquartile range, 5.0–9.7) months. Overall, 60.1 and 39.9% received nivolumab plus ipilimumab with and without chemotherapy, respectively. In these cohorts, the median age was 67 and 72 years; 10.8 and 35.5% were aged ≥75 years; 80.2 and 79.4% were male; 5.2 and 13.5% had a performance score ≥ 2; 32.1 and 27.0% developed grade 3–4 immune-related adverse events; treatment-related deaths were observed in 6 (2.8%) and 5 (3.5%) patients, respectively. Grade 3–4 immune-related adverse event incidence was the highest within the first month of treatment in both cohorts, although the immune-related adverse event risk persisted throughout. No new safety signals were observed at this interim analysis. The median progression-free survival was 6.0 (95% confidence interval, 5.2–7.6) and 5.8 (4.3–7.0) months in nivolumab plus ipilimumab with and without chemotherapy cohorts, respectively.

Conclusions
LIGHT-NING offers valuable insights into combination immunotherapy for untreated patients with stage IV or recurrent non-small cell lung cancer in Japanese real-world settings.
Availability of cancer survivorship support services across the National Cancer Institute Community Oncology Research Program network
Authors: Faro Jamie M , Dressler Emily V , Kittel Carol , Beeler Dori M , Bluethmann Shirley M , Sohl Stephanie J , McDonald Andrew M , Weaver Kathryn E , Nightingale Chandylen ,   Landscape Committee, Neuman Heather B , Nightingale Chandylen L , Parsons Susan K , Obeng-Gyasi Samilia , Cooley Mary E , Loh Kah Poh , Ramsey Scott D , McDonald Andrew M , Foust Melyssa , Braun-Inglis Christa , Kyono Wade T , Drescher Charles W , Wood Eden G , Dressler Emily V 
Published: January 2024

Abstract

Background
National cancer organizations recommend provision of nutrition, physical activity, and mental health supportive services to cancer survivors. However, the availability of these services across diverse community oncology settings remains unclear.

Methods
The National Cancer Institute Community Oncology Research Program (NCORP) is a national network of community oncology practices engaged in cancer research. The 2022 NCORP Landscape Assessment (5UG1CA189824) assessed individual practices’ establishment of survivorship clinics and nutrition, physical activity, and mental health services, resources, and/or referrals. Descriptive statistics summarized and logistic regression quantified the association between services, practice, and patient characteristics.

Results
Of 46 NCORP community sites, 45 (98%) responded to the survey, representing 259 adult practice groups. A total of 41% had a survivorship clinic; 96% offered mental health, 94% nutrition, and 53% physical activity services, resources, and/or referrals. All 3 services were offered in various formats (eg, in-house, referrals, education) by 51% and in-house only by 25% of practices. Practices with advanced practice providers were more likely to have a survivorship clinic (odds ratio [OR] = 3.19, 95% confidence interval [CI] = 1.04 to 9.76). Practices with at least 30% Medicare patients (OR = 2.54, 95% CI = 1.39 to 4.66) and more oncology providers (OR = 1.02, 95% CI = 1.01 to 1.04) were more likely to have all 3 services in any format. Practices with at least 30% Medicare patients (OR = 3.41, 95% CI = 1.50 to 7.77) and a survivorship clinic (OR = 2.84, 95% CI = 1.57 to 5.14) were more likely to have all 3 services in-house.

Conclusions
Larger oncology practices and those caring for more survivors on Medicare provided more supportive services, resources, and/or referrals. Smaller practices and those without survivorship clinics may need strategies to address potential gaps in supportive services.
Noncognitive religious influence and initiation in Tillson’s Children, Religion and the Ethics of Influence
Authors: Wareham Ruth J 
Published: January 2024

Abstract
In Children, Religion and the Ethics of Influence, John Tillson sets out a clear and convincing case for the view that children ought not to be initiated into religious faith by their parents or others with the relevant ‘extra-parental responsibilities’. However, by predicating his thesis on an understanding of illegitimate religious influence that largely equates initiation into faith with the inculcation of a distinctive type of propositional content, I contend that Tillson misses some of the potential harms such initiation may engender. Here I briefly explain why this is a problem before suggesting three ways he might respond to the criticism.
Damping of disco-seismic C-mode oscillations at the sonic radius of discs
Authors: Kato Shoji 
Published: January 2024

ABSTRACT
In a previous paper we have suggested that two-armed disc deformation excites two- or three-armed disco-seismic c-mode oscillations by three-mode resonant coupling processes. This might be one of possible causes of the QPOs observed in low-mass X-ray binaries and in black-hole sources. In another previous paper we showed that for these c-mode oscillations to be time periodic, they must satisfy some boundary conditions (regularity conditions) at the sonic point where accretion speed becomes transonic. In this paper we show that these boundary conditions acts so as to dampen the oscillations. This might be favourable for explaining why the QPOs are quasi-periodic.
A catalogue of Galactic GEMS: Globular cluster Extra-tidal Mock Stars
Authors: Grondin Steffani M , Webb Jeremy J , Lane James M M , Speagle Joshua S , Leigh Nathan W C 
Published: January 2024

ABSTRACT
This work presents the Globular cluster Extra-tidal Mock Star (GEMS) catalogue of extra-tidal stars and binaries created via three-body dynamical encounters in globular cluster cores. Using the particle-spray code Corespray, we sample $N=50\, 000$ extra-tidal stars and escaped recoil binaries for 159 Galactic globular clusters. Sky positions, kinematics, stellar properties, and escape information are provided for all simulated stars. Stellar orbits are integrated in seven different static and time-varying Milky Way gravitational potential models where the structure of the disc, perturbations from the Large Magellanic Cloud and the mass and sphericity of the Milky Way’s dark matter halo are all investigated. We find that the action coordinates of the mock extra-tidal stars are largely Galactic model independent, where minor offsets and broadening of the distributions between models are likely due to interactions with substructure. Importantly, we also report the first evidence for stellar stream contamination by globular cluster core stars and binaries for clusters with pericentre radii larger than five kiloparsecs. Finally, we provide a quantitative tool that uses action coordinates to match field stars to host clusters with probabilities. Ultimately, combining data from the GEMS catalogue with information of observed stars will allow for association of extra-tidal field stars with any Galactic globular cluster; a requisite tool for understanding population-level dynamics and evolution of clusters in the Milky Way.
Uncovering the formation of the counter-rotating stellar discs in SDSS J074834.64+444117.8
Authors: Bao Min , Chen Yanmei , Yang Meng , Zhu Ling , Shi Yong , Gu Qiusheng 
Published: January 2024

ABSTRACT
Using the integral field spectroscopic data from Mapping Nearby Galaxies at Apache Point Observatory survey, we study the kinematics and stellar population properties of the two counter-rotating stellar discs in a nearby galaxy SDSS J074834.64+444117.8. We disentangle the two stellar discs by three methods, including Ca ii λ8542 double Gaussian fit, penalized pixel fitting (pPXF) spectral decomposition, and orbit-based dynamical model. These three different methods give consistent stellar kinematics. The pPXF spectral decomposition provides the spectra of two stellar discs, with one being more luminous across the whole galaxy named primary disc, and the other named secondary disc. The primary disc is counter-rotating with ionized gas, while the secondary disc is co-rotating with ionized gas. The secondary disc has younger stellar population and poorer stellar metallicity than the primary disc. We estimate the stellar mass ratio between the primary and secondary discs to be ∼5.2. The DESI g, r, z colour image does not show any merger remnant feature in this galaxy. These findings support a scenario that the counter-rotating stellar discs in SDSS J074834.64+444117.8 formed through gas accretion from the cosmic web or a gas-rich companion.
Implication of kilometre-scale fluctuations on the MGS radio-occultation-derived electron density profiles: artefacts or ionospheric wave-like structures
Authors: Wan Xin , Zhong Jiahao , Wu Zhaopeng , Hao Yongqiang , Xiong Chao , Wang Hui , He Maosheng , Cui Jun , Liu Yiwen , Li Qiaoling , Kuai Jiawei 
Published: January 2024

ABSTRACT
This study investigates the vertical kilometre-scale fluctuations (KSFs) seen on the Mars Global Surveyor (MGS) radio-occultation (RO)-derived electron density profiles (EDPs) by wavelet spectrum analysis. A delicate five-peak signature is revealed: in the northern polar region near the dawn–dusk terminator, the amplitudes of the KSF peak at fixed altitudes with a constant separation of approximately 28 km. The feature could not be noticed on a single EDP; averaging with at least tens of continuously collected EDPs is needed, suggesting that the phenomenon is not instantaneous (time duration of each RO event is ∼7 min), but on a time-scale of days (observation time for tens of continuous RO events). Applying similar background criteria, Mars Atmosphere and Volatile EvolutioN (MAVEN) Radio Occultation Science Experiment derived EDPs could also occasionally capture similar multipeak features, indicating either that it is a natural ionospheric structure or that both MGS and MAVEN suffer the same artefact. The two indications are discussed, and a preliminary hypothesis is raised. A linear superposition with a 28 km standing wave might modulate the amplitude of KSF, and the 28 km standing wave might be associated with the ionospheric buoyancy waves disturbed by the upstream solar wind, while the plasma instabilities might trigger the KSF in the backgrounds of the draped magnetic field and day-to-night neutral winds.
Spin state and convex shape inversion from light curves of fast-rotating asteroids
Authors: Feng Shuai , Hu Shaoming , Chen Xu , Li Yang , Du Junju , Yang Zhitao , Cao Hai , Gan Qingbo , Liu Shuqi , Jiang Yuchen 
Published: January 2024

ABSTRACT
For fast-rotating asteroids, observed light curves could be very different from real light curves due to long exposure time. We present an improved observed light-curve model that accounts for long exposure time often encountered in observations of fast-rotating asteroids. By integrating brightness over time, we derive a more accurate observed light-curve model, allowing for better shape and spin state inversion results. Our analysis demonstrates that the fast-rotating model is more suitable for spin state inversion with longer exposure time, while the Kaasalainen model suffices for shorter exposure time. For spin state and shape inversion, exposure times of approximately 0.4P and 0.2P represent critical thresholds, respectively, beyond which the fast-rotating model exhibits superior performance. Notably, scattering parameters have minimal impact on the shape inversion results. These findings contribute valuable insights to the determination of shape and spin states for fast-rotating asteroids, shedding light on the challenges posed by long exposure time in such investigations.
On an apparent dearth of recurrent nova super-remnants in the Local Group
Authors: Healy-Kalesh M W , Darnley M J , Shara M M 
Published: January 2024

ABSTRACT
The Andromeda Galaxy is home to the annually erupting recurrent nova (RN) M 31N 2008-12a (12a); the first nova found to host a nova super-remnant (NSR). An NSR is an immense structure surrounding a RN, created from many millions of eruptions sweeping up material in the local environment to form a shell tens of parsecs across. Theory has demonstrated that NSRs should be found around all recurrent novae (RNe), even those systems with long periods between eruptions. Befittingly, the second NSR was found around the Galactic classical (and long suspected recurrent) nova, KT Eridani. In this Paper, we aim to find more of these phenomena through conducting the first ever survey for NSRs in M 31 and the Large Magellanic Cloud (LMC). We find that the surroundings of fourteen RNe in M 31 as well as the surroundings of the four RNe in the LMC do not show any evidence of vast parsec-scale structures in narrow-band (H α and $[{\rm S\, {\small II}}]$) images, unlike the one clearly seen around 12a, and therefore conclude that observable NSRs are either rare structures, or they are too faint (or small) to be detected in our existing data sets. Yet, the NSR surrounding 12a would also likely to have been overlooked in our study if it were approximately one magnitude fainter. Searches for NSRs around other RNe ‘masquerading’ as classical novae may prove to be fruitful as would whole surveys of other Local Group galaxies.
The VLBA CANDELS GOODS-North Survey – I. survey design, processing, data products, and source counts
Authors: Deane Roger P , Radcliffe Jack F , Njeri Ann , Akoto-Danso Alexander , Bernardi Gianni , Smirnov Oleg M , Beswick Rob , Garrett Michael A , Jarvis Matt J , Whittam Imogen H , Bourke Stephen , Paragi Zsolt 
Published: January 2024

ABSTRACT
The past decade has seen significant advances in wide-field cm-wave very long baseline interferometry (VLBI), which is timely given the wide-area, synoptic survey-driven strategy of major facilities across the electromagnetic spectrum. While wide-field VLBI poses significant post-processing challenges that can severely curtail its potential scientific yield, many developments in the km-scale connected-element interferometer sphere are directly applicable to addressing these. Here we present the design, processing, data products, and source counts from a deep (11 μJy beam−1), quasi-uniform sensitivity, contiguous wide-field (160 arcmin2) 1.6 GHz VLBI survey of the CANDELS GOODS-North field. This is one of the best-studied extragalactic fields at milli-arcsecond resolution and, therefore, is well-suited as a comparative study for our Tera-pixel VLBI image. The derived VLBI source counts show consistency with those measured in the COSMOS field, which broadly traces the AGN population detected in arcsecond-scale radio surveys. However, there is a distinctive flattening in the S1.4GHz ∼100–500 μJy flux density range, which suggests a transition in the population of compact faint radio sources, qualitatively consistent with the excess source counts at 15 GHz that is argued to be an unmodelled population of radio cores. This survey approach will assist in deriving robust VLBI source counts and broadening the discovery space for future wide-field VLBI surveys, including VLBI with the Square Kilometre Array, which will include new large field-of-view antennas on the African continent at ≳1000 km baselines. In addition, it may be useful in the design of both monitoring and/or rapidly triggered VLBI transient programmes.
X-ray variability of SDSS quasars based on the SRG/eROSITA all-sky survey
Authors: Prokhorenko S A , Sazonov S Yu , Gilfanov M R , Balashev S A , Bikmaev I F , Ivanchik A V , Medvedev P S , Starobinsky A A , Sunyaev R A 
Published: January 2024

ABSTRACT
We examine the long-term (rest-frame time-scales from a few months to ∼20 yr) X-ray variability of a sample of 2344 X-ray bright quasars from the Sloan Digital Sky Survey (SDSS) data release 14 quasar (DR14Q) catalogue, based on the data of the Spectrum-Roentgen-Gamma (SRG)/eROSITA All-Sky Survey complemented for ∼7 per cent of the sample by archival data from the XMM–Newton Serendipitous Source Catalogue. We characterize variability by a structure function, SF2(Δt). We confirm the previously known anticorrelation of the X-ray variability amplitude with luminosity. We also study the dependence of X-ray variability on black hole mass, MBH, and on an X-ray-based proxy of the Eddington ratio, λX. Less massive black holes prove to be more variable for given Eddington ratio and time-scale. X-ray variability also grows with decreasing Eddington ratio and becomes particularly strong at λX of less than a few per cent. We confirm that the X-ray variability amplitude increases with increasing time-scale. The SF2(Δt) dependence can be satisfactorily described by a power law, with the slope ranging from ∼0 to ∼0.4 for different (MBH, λX) subsamples (except for the subsample with the lowest black hole mass and Eddington ratio, where it is equal to 1.1 ± 0.4).
Two-dimensional kinematics and dynamical modelling of the ‘Jackpot’ gravitational lens from deep MUSE observations
Authors: Turner Hannah C , Smith Russell J , Collett Thomas E 
Published: January 2024

ABSTRACT
We present results from the first spatially resolved kinematic and dynamical modelling analysis of the unique SDSSJ0946+1006 (‘Jackpot’) triple-source lens system, where a single massive foreground $z\, =\, 0.222$ galaxy multiple-images three background sources at different redshifts. Deep integral field unit spectroscopic data were obtained using the MUSE instrument on the VLT, which, compared to previous single-slit observations, provides full azimuthal area coverage, high sensitivity (5 h integration) and high angular resolution (0.5 arcsec full width at half-maximum). To account for the strong continuum contributions from the $z\, =\, 0.609$ source, a multiple-component stellar template fitting technique is adopted to fit to the spectra of both the lens galaxy and the bright lensed background arc simultaneously. Through this, we robustly measure the first and second moments of the 2D stellar kinematics out to about 10 kpc from the centre of the lens, as well as resolving the inner profile inwards to ∼1 kpc. The 2D kinematic maps show a steep velocity dispersion gradient and a clear rotational component. We constrain the characteristic properties of the stellar and dark matter (DM) mass components with a sufficiently flexible parametrised dynamical model and an imposed lensing mass and find a DM density slope of $\gamma \, =\, 1.73\substack{+0.17 \\ -0.26}$, i.e. significantly steeper than an unmodified NFW profile ($\gamma \, =\, 1$) and consistent with a contracted DM halo. Our fitted models have a lensing-equivalent density slope of $\eta \, =\, 0.96\pm 0.02$, and thus we confirm most pure lensing results in finding a near isothermal profile for this galaxy.