bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eleven rules for a more successful clinical psychology
Authors: Hayes Steven C. 
Published: June 2005

AbstractThe recommendations put forth in the target article, “Twenty‐First Century Graduate Education in Clinical Psychology: A Four Level Matrix Model” (C.R. Snyder & T.R. Elliott, this issue), should be regarded in the context of the large need to develop a more progressive and effective discipline. No amount of “brute force” education and empiricism is certain to solve the problems of the scope of our field identified by the authors. Eleven rules are offered and defended that may lead to a more practically and empirically successful field. © 2005 Wiley Periodicals, Inc. J Clin Psychol.
An attachment theory perspective on the proposed matrix model
Authors: Shorey Hal S. 
Published: June 2005

AbstractThe matrix model (C.R. Snyder & T.R. Elliott, this issue) advocates an increased grounding of clinical psychology graduate students in theory. The matrix model is theory‐based in the ways that it advances this goal. Accordingly, evaluating the matrix model from an extant theoretical perspective should shed light on its applicability and utility as an educational framework. The present attachment theory perspective on the matrix model demonstrates that it meets its stated goals in that it possesses adequate (a) breadth in incorporating theory from across subdisciplines in psychology, and (b) depth in how it facilitates conceptualizing clients and research participants at the intrapersonal, interpersonal, and societal levels. The benefits for incorporating the matrix model in clinical psychology graduate programs are discussed. © 2005 Wiley Periodicals, Inc. J Clin Psychol.
A team effort: Reply to Snyder and Elliott
Authors: Hendrick Susan S. 
Published: June 2005

AbstractThis response to C.R. Snyder and T.R. Elliott's innovative proposals for training (this issue) highlights areas of agreement with the authors as well as encourages greater attention to several issues. These include counseling psychology and its historical emphasis on wellness, mentoring training for current faculty as well as graduate students, and appreciation for the diverse areas within psychology as well as within the broader social sciences (e.g., social work, marriage and family therapy) as contributors to such training. © 2005 Wiley Periodicals, Inc. J Clin Psychol.
Following the money: Economic inhibitors of change affecting graduate education in clinical psychology
Authors: Koocher Gerald P. 
Published: June 2005

AbstractC.R. Snyder and T.R. Elliott (this issue) offer a thoughtful and elaborate model for future training in graduate clinical psychology, couched in visionary optimism. However, they interpret history and present trends in a manner that seems to ignore the realistic demands of economic forces. They propose thoughtful, constructive, pro‐social directions, but seem at least partially oblivious to underlying economic forces destined to impede meaningful implementation of their model. © 2005 Wiley Periodicals, Inc. J Clin Psychol.
Re‐envisioning the training and practice of clinical psychologists: Preserving science and research orientations in the face of change
Authors: Cook Joan M. , Coyne James C. 
Published: June 2005

AbstractWe argue for preservation of an expectation of psychologists that approach human problems from an evidence‐based perspective. Acquisition of the requisite knowledge, skills, and practical experience require access to resources outside of graduate psychology programs. Whether adhering to a scientist–practitioner or practitioner–scholar model, psychologists must be “scientifically literate.” Deficiencies are noted in the training of scientist–practitioner psychologists for the conduct of clinical trials and the dissemination and sustained implementation of evidence‐based interventions. © 2005 Wiley Periodicals, Inc. J Clin Psychol.
Progesterone primes zona pellucida‐induced activation of phospholipase A2 during acrosomal exocytosis in guinea pig spermatozoa
Authors: Shi Qi‐xian , Chen W.Y. , Yuan Y.Y. , Mao L.Z. , Yu S.Q. , Chen A.J. , Ni Y. , Roldan E.R.S. 
Published: June 2005

AbstractWe investigated, using guinea‐pig spermatozoa as a model, whether phospholipase A2 (PLA2) is involved in progesterone or zona pellucida (ZP)‐stimulated acrosomal exocytosis, if progesterone enhances ZP‐induced activation of PLA2, and mechanisms underlying PLA2 regulation. Spermatozoa were capacitated and labeled in low Ca2+ medium with [14C]choline chloride or [14C]arachidonic acid, washed, and then exposed to millimolar Ca2+ and progesterone and/or ZP. Each agonist stimulated decrease of phosphatidylcholine (PC) and release of arachidonic acid and lysoPC, indicative of PLA2 activation. Aristolochic acid (a PLA2 inhibitor) abrogated lipid changes and exocytosis, indicating that these lipid changes are essential for exocytosis. Exposure of spermatozoa to submaximal concentrations of both progesterone and ZP resulted in a synergistic increase of arachidonic acid and lysoPC releases, and exocytosis, suggesting that, under natural conditions, both agonists interact to bring about acrosomal exocytosis. Progesterone‐induced PLA2 activation appears to be mediated by a GABAA‐like receptor, because bicuculline (a GABAA receptor antagonist) blocked arachidonic acid release and exocytosis. In agreement with this, GABA mimicked progesterone actions. ZP‐induced activation of PLA2 seemed to be transduced via Gi proteins because pertussis toxin blocked arachidonic acid release and acrosomal exocytosis. PLA2 may be regulated by PKC because progesterone‐ or ZP‐induced release of arachidonic acid was blocked by the PKC inhibitors staurosporine or chelerythrine chloride. PLA2 could also be regulated by the cAMP‐PKA pathway; inclusion of the PKA inhibitor 14–22 amide or H‐89 led to a reduction in arachidonic acid release or exocytosis after progesterone or ZP. Taken together, these results suggest that PLA2 plays an essential role in progesterone or ZP‐stimulated exocytosis with progesterone priming ZP action. © 2005 Wiley‐Liss, Inc.
CXCL12 (SDF‐1) and CXCL13 (BCA‐1) chemokines significantly induce proliferation and collagen type I expression in osteoblasts from osteoarthritis patients
Authors: Lisignoli Gina , Toneguzzi Stefania , Piacentini Anna , Cristino Sandra , Grassi Francesco , Cavallo Carola , Facchini Andrea 
Published: June 2005

AbstractTo evaluate the role of CXC chemokines CXCL8 (IL8), CXCL10 (IP‐10), CXCL12 (SDF‐1), and CXCL13 (BCA‐1) in bone remodeling, we analyzed their effects on osteoblasts (OBs) obtained from subchondral trabecular bone tissue of osteoarthritis (OA) and post‐traumatic (PT) patients. The expression of CXC receptors/ligands (CXCR1/CXCL8, CXCR2/CXCL8, CXCR3/CXCL10, CXCR4/CXCL12, and CXCR5/CXCL13) was analyzed in cultured OBs by flow cytometry and immunocytochemistry. Functional assays on CXC chemokine‐treated‐OBs in the presence or absence of their specific inhibitors were performed to analyze cellular proliferation and the enzymatic response to chemokine activation. The expression of chemokine ligands/receptors was also confirmed in bone tissue samples by immunohistochemical analysis. Collagen type I and alkaline phosphatase mRNA expression were analyzed on CXCL12‐ and CXCL13‐treated OBs by real‐time PCR. OBs from both OA and PT patients expressed high levels of CXCR3 and CXCR5 and lower amounts of CXCR1 and CXCR4. CXCL12 and CXCL13, only in OBs from OA patients, induced a significant proliferation that was also confirmed by specific blocking experiments. Moreover, OBs from OA patients released a higher amount of CXCL13 than those of PT patients while no differences were found for CXCL12. In the remodeling area of bone tissue samples, immunohistochemical analysis confirmed that OBs expressed CXCL12/CXCR4 and CXCL13/CXCR5 both in OA and PT samples. CXCL12 and CXCL13 upregulated collagen type I mRNA expression in OBs from OA patients. These data suggest that CXCL12 and CXCL13 may directly modulate cellular proliferation and collagen type I in OA patients, so contributing to the remodeling process that occurs in the evolution of this disease. © 2005 Wiley‐Liss, Inc.
Crossing numbers of Sierpiński‐like graphs
Authors: Klavžar Sandi , Mohar Bojan 
Published: June 2005

AbstractCrossing numbers of Sierpiński graphs S(n,k) and their regularizations S+(n,k) and S++(n,k) are studied. Drawings of these graphs are presented and proved to be optimal for S+(n,k) and S++(n,k) for every n ≥ 1 and k ≥ 1. The crossing numbers of these graphs are expressed in terms of the crossing number of Kk+1. These are the first nontrivial families of graphs of “fractal” type whose crossing number is known. © 2005 Wiley Periodicals, Inc. J Graph Theory
Synthesis of polyetherols with purine ring. Kinetics and mechanisms of reactions, part 1: Reaction of hydroxymethyl derivatives of uric acid with oxiranes
Authors: Cisek‐Cicirko Irmina , Lubczak Jacek 
Published: June 2005

AbstractThe kinetics and mechanisms of the initial steps of formation of polyetherols from hydroxymethyl derivatives of uric acid and oxiranes were studied. It has been found that initial steps of the reaction of polyetherol formation occur without a catalyst. The NH groups, which are formed upon release of formaldehyde from N‐ and O‐hydroxymethyl derivatives of uric acid, take part in the reaction. © 2005 Wiley Periodicals, Inc. Int J Chem Kinet 37: 464–471, 2005
Twitch airway pressure elicited by magnetic phrenic nerve stimulation in anesthetized healthy children
Authors: Rafferty Gerrard F. , Mustfa Naveed , Man William D. , Sylvester Karl , Fisher Antony , Plaza Miguel , Davenport Mark , Blaney Sean , Moxham John , Greenough Anne 
Published: June 2005

AbstractChildren with diaphragm dysfunction may be unable to maintain adequate ventilation. Accurate diagnosis is important, but can only be achieved using an appropriate test and reference range. The aim of this study, therefore, was to measure diaphragm contractility and examine the influence of age and maturation, using magnetic phrenic nerve stimulation in healthy children. Anterolateral magnetic stimulation (MS) of the phrenic nerves was performed using a 43‐mm figure‐eight coil in 23 children (14 male; mean age, 7.8 years; range, 1.8–15.7) anesthetized for minor surgery with sevoflurane gas. The airway was maintained with a cuffed laryngeal mask airway (LMA) which was briefly occluded during MS. Diaphragm contractility was assessed by measuring the airway pressure (TwPaw) elicited by MS. TwPaw responses were obtained in all subjects, with mean (SD) TwPaw 18.2 (6.8) cm H2O bilateral, 7.3 (3.2) cm H2O left unilateral, and 8.6 (3.1) cm H2O right unilateral. Subgroup analysis was performed in 17 of the children who were prepubertal. Their mean (SD) TwPaw was 17.3 (6.8) cm H2O bilateral, 7.1 (3.7) cm H2O left unilateral, and 8.3 (3.3) right unilateral. The mean (SD) intrapatient coefficients of variation for bilateral and left and right unilateral TwPaw were 8.4% (5.2), 6.7% (3.5), and 11.7% (10.3), respectively. Bilateral and left and right unilateral TwPaw were significantly related to age (P < 0.05). In healthy prepubertal children, diaphragm contractility is primarily influenced by age. Pediatr Pulmonol. 2005; 40:141–147. © 2005 Wiley‐Liss, Inc.
Benzidine photodegradation: a mass spectrometry and UV spectroscopy combined study
Authors: Madeira Paulo , Nunes M. R. , Borges C. , Costa F. M. A. , Florêncio M. H. 
Published: June 2005

AbstractThe benzidine photodegradation process was studied using UV/Vis spectroscopy and electrospray ionization mass spectrometry (ESI‐MS) combined with collision‐induced dissociation (CID) and tandem mass spectrometry (MS/MS). Mass spectrometry was used to characterize benzidine and to identify and characterize possible degradation products and intermediates. The MS data showed that benzidine is quite persistent in aqueous medium. Moreover, the MS analysis enabled us to propose the following three degradation products/intermediates: 4′‐nitro‐4‐biphenylamine, tetrahydroxybiphenyl and 4,4′‐dinitrobiphenyl. For the benzidine molecular ion and protonated molecule and for the protonated molecules of the degradation products/intermediates detected, fragmentation patterns are proposed based on CID and MS/MS data. For the photodegradation process different catalysts were used, namely the commercial TiO2 Degussa P25, and the laboratory‐prepared ZnO, TiO2 anatase and a titanium‐zinc oxide with a perovskite type structure. Comparison of the different catalysts showed that degradation was favoured with the commercial TiO2. Nevertheless, the other catalysts appear to be promising and economic alternatives for potential future remediation studies. Copyright © 2005 John Wiley & Sons, Ltd.
“Rugby Finger”—Avulsion of Profundus of Ring Finger
Authors: LUNN P. G. , LAMB D. W. 
Published: June 2005

The results of tendon grafting following avulsion of the profundus tendon to the ring finger (“Rugby finger”) are described. Function in the hand was improved in all cases and this is a method of treatment which should be considered by the surgeon experienced in tendon grafting in those patients who are young and well motivated. The exact reason for the common involvement of the ring finger is not clear but the unique lumbrical origin from that profundus may be an important factor tethering the tendon in the palm, and this is suggested as the possible cause of this injury.
Ultrastructure of Solitary Enchondromas
Authors: ZIMNY MARILYN L. , REDLER I. 
Published: June 2005

Solitary enchondromas obtained from the small bones of the hand were studied with transmission electron microscopy. Three cell types were seen as follows: (1) young looking, active cells with extensive dilated rough endoplasmic reticulum and well defined Golgi and mitochondria; (2) older looking, degenerating cells with dilated rough endoplasmic reticulum, well defined Golgi, glycogen masses, vacuoles containing tropocollagen, lipid and myelin figures; and (3) dying cells showing loss of cell membrane and lysosomal-like bodies. A young chondroblastic cell may try to mature, become a normal chondrocyte that produces normal matrix but it does not succeed and dies. Enchondromal cells are not capable of forming tropocollagen or synthesizing proteoglycans for the matrix.
An Open Twin Incision Technique of Carpal Tunnel Decompression with Reduced Incidence of Scar Tenderness
Authors: BIYANI A. , DOWNES E. M. 
Published: June 2005

We retrospectively compared a single curved incision for carpal tunnel decompression (group A, 29 wrists in 26 patients) with a twin incision technique (group B, 34 wrists in 30 patients), leaving an intact bridge of skin at the base of the palm. Patients in group B reported statistically significant subjective improvement in the early post-operative period, with fewer residual symptoms and earlier recovery of function compared to patients in group A. After a mean post-operative period of 23 months, 5/29 wrists were symptomatic in group A compared to 1/34 wrists in group B at 13 months, but this was not statistically significant. The twin incision technique is easy to perform and allows rapid post-operative recovery. The incidence of scar tenderness is reduced as palmar cutaneous branches of the median nerve are avoided. Because the distal portion of the transverse carpal ligament is divided under direct vision, this technique is not associated with any significant neurovascular complications.
Improved Method for the Growth of Yttrium-Iron and Yttrium-Gallium Garnets
Authors: Nielsen J. W. 
Published: June 2005

Large single crystals of yttrium and rare earth iron garnets, and yttrium and rare earth gallium garnets,have been grown from molten solutions of lead oxide and lead fluoride. The crystals are grown by slowly cooling melts from about 1260°C to near 950°C. Sample compositions are: for YIG, 8 mole % Y2O3, 22 mole% Fe2O3, 30 mole % PbO and 40 mole % PbF2; for YGaG, 5.8 mole % Y2O3, 14 mole % Ga2O3, 39.4 mole% PbO and 40.8 mole % PbF2.
This method provides crystals both large in size and of superior quality. Best results are obtained when the containing crucible is hotter near its top than at its base since nucleation is thereby reduced.
New Material for Permanent Magnets on a Base of Mn and Al
Authors: Koch A. J. J. , Hokkeling P. , v. d. Steeg M. G. , de Vos K. J. 
Published: June 2005

During an investigation of the Mn-Al system from 40–100% Mn, a new metastable phase was found,which has a tetragonal structure with lattice constants a = 2.77 A and c = 3.57 A and lattice positions 000 and 121212 with a preference of the Mn atoms for one of these positions. This τ phase, which has the approximate composition Mn1.11 Al0.89, can only be obtained by special heat treatment. It possesses remarkable magnetic properites. From the approach to saturation an anisotropy constant of about 107 ergs/cm3 can be calculated, while the extrapolated value σ∞ amounts to 96 erg/oe g; the latter corresponds to a 4πIs of 6200 G.
Particles obtained by grinding the bulk material possess an HCI value of up to 6000 oe. No fixed correlation exists between particle size and the value of HCI; the latter is strongly dependent on the method of pulverization, and the authors are inclined to think that HCI is largely determined by the extent of deformation.
The increase of HCI caused by grinding is accompanied by a decrease of the magnetic moment. This decrease can be partially reversed by aging. The observed decrease in the magnetic moment on pulverizing agrees with the value calculated from X-ray and neutron diffraction data. The current fine-particle theory is unable to give an adequate explanation of the HCI.
An anisotropic permanent magnet was obtained by swaging cast bars, with the following properties in the preferred direction: Br = 4280 G, HCI = 4600 oe, HCB = 2750 oe, BHmax = 3.5×106 G oe.
Magnetic resonance imaging as a sole method for the morphological and functional evaluation of live kidney donors
Authors: El‐Diasty Tarek A. , El‐Ghar Mohamed E. Abo , Shokeir Ahmed A. , Gad Hossam M. , Wafa Ehab W. , El‐Azab Mohamed E. , El‐Din Ahmed B. Shehab , Ghoneim Mohamed A. 
Published: June 2005

In this section, authors from Mansoura describe their experience with MRI as the sole method for the morphological and functional evaluation of live kidney donors. They recommend this technique in both instances.A series of studies from Detroit show that oxalate and hyperoxaluria induced free‐radical generation, which resulted in injury to renal tubular cells. In this paper they show for the first time that hyperoxaluria‐induced injury promotes individual calcium oxalate crystal attachment in the renal tubules. They also showed that this was prevented by vitamin E treatment.OBJECTIVETo evaluate gadolinium‐enhanced dynamic magnetic resonance imaging (MRI) as the sole method for the anatomical and functional assessment of potential live‐kidney donors.SUBJECTS AND METHODSThe study included 50 consecutive kidney donors; in addition to routine donor evaluation, the kidney was imaged with Gd‐enhanced dynamic MRI, which was also used for selectively determining the glomerular filtration rate (GFR) of each kidney. All donors had a m99Tc‐mercaptoacetyltriglycine (MAG3) renal scan as the reference standard to measure GFR. The anatomical results of MRI were compared with the findings at donor nephrectomy, and the GFR estimated from MRI compared with that from MAG3 scintigraphy.RESULTSMR angiography had 100% sensitivity, 94% specificity and 96% overall accuracy for detecting the number of renal arteries, and 100% sensitivity, 98% specificity and 98% overall accuracy for the number of renal veins. There was a close correlation (r = 0.54, P < 0.01) between the GFR of each kidney estimated by MRI or MAG3. For the right and left kidneys the mean isotope clearance was not significantly different from that of mean MRI clearance. MR urography allowed visualization of the urinary tract and the detection of any abnormality.CONCLUSIONGd‐enhanced dynamic MRI can provide accurate information about the anatomy of the urinary tract and vasculature of the kidney, and can be used to accurately estimate the selective GFR of each kidney. Therefore, we recommend MRI as a single imaging diagnostic method for assessing potential live kidney donors.
Differential effects of proteasome inhibition by bortezomib on murine acute graft-versus-host disease (GVHD): delayed administration of bortezomib results in increased GVHD-dependent gastrointestinal toxicity
Authors: Sun Kai , Wilkins Danice E. C. , Anver Miriam R. , Sayers Thomas J. , Panoskaltsis-Mortari Angela , Blazar Bruce R. , Welniak Lisbeth A. , Murphy William J. 
Published: June 2005

AbstractWe have recently demonstrated that the proteasome inhibitor, bortezomib, administered immediately following murine allogeneic bone marrow transplantation (BMT) resulted in marked inhibition of acute graft-versus-host disease (GVHD) with retention of graft-versus-tumor effects. We now assessed the effects of delayed bortezomib administration (5 or more days after BMT) on GVHD. Recipient C57BL/6 (H2b) mice were lethally irradiated and given transplants of bone marrow cells and splenocytes from major histocompatibility complex (MHC)–disparate BALB/c (H2d) donors. In marked contrast to the effects of bortezomib on GVHD prevention when administered immediately after BMT, delayed bortezomib administration resulted in significant acceleration of GVHD-dependent morbidity. No toxicity was observed following delayed bortezomib administration in models where donor T cells were not coadministered, indicating that these deleterious effects were critically dependent on GVHD induction. The increase in GVHD susceptibility even occurred when late administration of bortezomib was preceded by early administration. Pathologic assessment revealed that significant increases in gastrointestinal lesions occurred following delayed bortezomib administration during GVHD. This pathology correlated with significant increases of type 1 tumor necrosis factor α (TNF-α) receptor transcription in gastrointestinal cells and with significant increases of TNF-α, interleukin 1β (IL-1β), and IL-6 levels in the serum. These results indicate that the differential effects of proteasome inhibition with bortezomib on GVHD are critically dependent on the timing of bortezomib administration.
pSLIP: SVM based protein subcellular localization prediction using multiple physicochemical properties
Authors: Sarda Deepak , Chua Gek Huey , Li Kuo-Bin , Krishnan Arun 
Published: June 2005

Abstract
Background
Protein subcellular localization is an important determinant of protein function and hence, reliable methods for prediction of localization are needed. A number of prediction algorithms have been developed based on amino acid compositions or on the N-terminal characteristics (signal peptides) of proteins. However, such approaches lead to a loss of contextual information. Moreover, where information about the physicochemical properties of amino acids has been used, the methods employed to exploit that information are less than optimal and could use the information more effectively.

Results
In this paper, we propose a new algorithm called pSLIP which uses Support Vector Machines (SVMs) in conjunction with multiple physicochemical properties of amino acids to predict protein subcellular localization in eukaryotes across six different locations, namely, chloroplast, cytoplasmic, extracellular, mitochondrial, nuclear and plasma membrane. The algorithm was applied to the dataset provided by Park and Kanehisa and we obtained prediction accuracies for the different classes ranging from 87.7% – 97.0% with an overall accuracy of 93.1%.

Conclusion
This study presents a physicochemical property based protein localization prediction algorithm. Unlike other algorithms, contextual information is preserved by dividing the protein sequences into clusters. The prediction accuracy shows an improvement over other algorithms based on various types of amino acid composition (single, pair and gapped pair). We have also implemented a web server to predict protein localization across the six classes (available at http://pslip.bii.a-star.edu.sg/).