bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Accessory Renal Arteries on Essential Hypertension and Related Mechanisms
Authors: Wu Fengyuan , Yuan Xiaoyang , Sun Kaiwen , Zhang Ying , Zhu Lianxin , Bai Cuiping , Cheng Yunpeng , Lu Yan , Jiang Yinong , Song Wei 
Published: February 2024

Background
This case‐control study aimed to determine whether there were differences between patients with essential hypertension with accessory renal arteries (ARAs) and those without ARAs.

Methods and Results

The enrolled patients with essential hypertension were divided into the ARA group (n=200) and control group without ARAs (n=238). After propensity matching, 394 patients (197 in each of the 2 groups), were included. The 24‐hour BP (4.33/2.43 mm Hg) and daytime BP (4.48/2.61 mm Hg) of patients in the ARA group were significantly higher than those of the control group (
P
<0.05). The flow‐mediated dilation was lower in the ARA group (5.98±2.70 versus 5.18±2.66;
P
<0.05). In correlation analysis, the horizontal plasma aldosterone concentration had the highest correlation with 24‐hour, daytime, and nighttime systolic BP (
r
=0.263, 0.247, and 0.243, respectively;
P
<0.05) and diastolic BP (
r
=0.325, 0.298, and 0.317, respectively;
P
<0.05). As for multivariate regression analysis, plasma aldosterone concentration was a significant risk factor for elevated 24‐hour, daytime, and nighttime systolic BP (β=0.249 [95% CI, 0.150–0.349], 0.228 [95% CI, 0.128–0.329], and 0.282 [95% CI, 0.187–0.377], respectively;
P
<0.05) and elevated diastolic BP (β=0.289 [95% CI, 0.192–0.385], 0.256 [95% CI, 0.158–0.353], and 0.335 [95% CI, 0.243–0.427], respectively;
P
<0.05). Direct renin concentration was also a risk factor for 24‐hour and daytime BPs, whereas heart rate was a risk factor correlated with 24‐hour, daytime, and nighttime diastolic BP (all
P
<0.05). For the mixed‐effects model for repeated measures, the results were similar to results of the multivariate regression analysis (all
P
<0.05).

Conclusions
ARAs could contribute a higher BP of patients with essential hypertension and might promote the development of essential hypertension. The mechanism might be related to overactivation of the renin‐angiotensin‐aldosterone system and sympathetic nervous system.
Age‐Related Differences in Takotsubo Syndrome: Results From the Multicenter GEIST Registry
Authors: El‐Battrawy Ibrahim , Santoro Francesco , Núñez‐Gil Iván J. , Pätz Toni , Arcari Luca , Abumayyaleh Mohammad , Guerra Federico , Novo Giuseppina , Musumeci Beatrice , Cacciotti Luca , Mariano Enrica , Caldarola Pasquale , Parisi Giuseppe , Montisci Roberta , Vitale Enrica , Volpe Massimo , Corbì‐Pasqual Miguel , Martinez‐Selles Manuel , Almendro‐Delia Manuel , Sionis Alessandro , Uribarri Aitor , Thiele Holger , Brunetti Natale Daniele , Eitel Ingo , Akin Ibrahim , Stiermaier Thomas 
Published: February 2024

Background
The role of age in the short‐ and long‐term prognosis of takotsubo syndrome (TTS) is controversial. The aim of the present study was to evaluate age‐related differences and prognostic implications among patients with TTS.

Methods and Results

In total, 2492 consecutive patients with TTS enrolled in an international registry were stratified into 4 groups (<45, 45–64, 65–74, and ≥75 years). The median long‐term follow‐up was 480 days (interquartile range, 83–1510 days). The primary outcome was all‐cause mortality (in‐hospital and out‐of‐hospital mortality). The secondary end point was TTS‐related in‐hospital complications. Among the 2479 patients, 58 (2.3%) were aged <45 years, 625 (25.1%) were aged 45 to 64 years, 733 (29.4%) were aged 65 to 74 years, and 1063 (42.6%) were aged ≥75 years. Young patients (<45 years) had a higher prevalence of men (from youngest to oldest, 24.1% versus 12.6% versus 9.7% versus 11.4%;
P
<0.01), physical triggers (46.6% versus 27.5%, 33.9%, and 38.4%;
P
<0.01), and non‐apical forms of TTS (25.9% versus 23.7%, 12.7%, and 9%;
P
<0.01) than those aged 45 to 64, 65 to 74, and ≥75 years. During hospitalization, young patients experienced a higher rate of in‐hospital complications (32.8% versus 23.4%, 27.4%, and 31.9%;
P
=0.01), but in‐hospital mortality was higher in the older group (0%, 1.6%, 2.9%, and 5%;
P
=0.001). Long‐term all‐cause mortality was significantly higher in the older cohort (5.6%, 6.4%, 11.3%, and 22.3%; log‐rank
P
<0.001), as was long‐term cardiovascular mortality (0%, 0.9%, 1.9%, and 3.2%; log‐rank
P
=0.01).

Conclusions
Young patients with TTS have a typical phenotype characterized by a higher prevalence of male sex, non‐apical ballooning patterns, and in‐hospital complications. However, in‐hospital and long‐term mortality are significantly lower in young patients with TTS.

Registration

URL:
https://classic.clinicaltrials.gov/ct2/show/NCT04361994
. Unique identifier: NCT04361994.
Incidental Arrhythmias During Atrial Fibrillation Screening With Repeat 7‐Day Holter ECGs in a Hospital‐Based Patient Population
Authors: Goulouti Eleni , Lam Anna , Nozica Nikolas , Elchinova Elena , Dernektsi Chrisoula , Neugebauer Felix , Branca Mattia , Servatius Helge , Noti Fabian , Haeberlin Andreas , Thalmann Gregor , Kozhuharov Nikola Asenov , Madaffari Antonio , Tanner Hildegard , Reichlin Tobias , Roten Laurent 
Published: February 2024

Background
Screening for atrial fibrillation (AF) may reveal incidental arrhythmias of relevance. The aim of this study was to describe incidental arrhythmias detected during screening for AF in the STAR‐FIB (Predicting SilenT AtRial FIBrillation in Patients at High Thrombembolic Risk) cohort study.

Methods and Results
In the STAR‐FIB cohort study, we screened hospitalized patients for AF with 3 repeat 7‐day Holter ECGs. We analyzed all Holter ECGs for the presence of the following incidental arrhythmias: (1) sinus node dysfunction, defined as sinus pause of ≥3 seconds’ duration; (2) second‐degree (including Wenckebach) or higher‐degree atrioventricular block (AVB); (3) sustained supraventricular tachycardia of ≥30 seconds’ duration; and (4) sustained ventricular tachycardia of ≥30 seconds’ duration. We furthermore report treatment decisions because of incidental arrhythmias. A total of 2077 Holter ECGs were performed in 794 patients (mean age, 74.7 years; 49% women), resulting in a mean cumulative duration of analyzable ECG signal of 414±136 hours/patient. We found incidental arrhythmias in 94 patients (11.8%). Among these were sinus node dysfunction in 14 patients (1.8%), AVB in 41 (5.2%), supraventricular tachycardia in 42 (5.3%), and ventricular tachycardia in 2 (0.3%). Second‐degree AVB was found in 23 patients (2.9%), 2:1 AVB in 10 (1.3%), and complete AVB in 8 (1%). Subsequently, 8 patients underwent pacemaker implantation, 1 for sinus node dysfunction (post‐AF conversion pause of 9 seconds) and 7 for advanced AVB. One patient had an implantable cardioverter‐defibrillator implanted for syncopal ventricular tachycardia.

Conclusions
Incidental arrhythmias were frequently detected during screening for AF in the STAR‐FIB study and resulted in device therapy in 1.1% of our cohort patients.
Volunteer Responder Interventions in Out‐of‐Hospital Cardiac Arrest in Urban, Suburban, and Rural Areas
Authors: Kragh Astrid Rolin , Gregers Mads Tofte , Andelius Linn , Grabmayr Anne Juul , Kollander Louise , Kjærulf Victor Elnegaard , Kjølbye Julie Samsøe , Sheikh Annam Pervez , Ersbøll Annette Kjær , Folke Fredrik , Hansen Carolina Malta 
Published: February 2024

Background
Patients with out‐of‐hospital cardiac arrest (OHCA) in rural areas experience longer emergency response times and have lower survival rates compared with patients in urban areas. Volunteer responders might improve care and outcomes for patients with OHCA specifically in rural areas. Therefore, we investigated volunteer responder interventions based on the degree of urbanization.

Methods and Results
We included 1310 OHCAs from 3 different regions in Denmark where volunteer responders had arrived at the OHCA location. The location was classified as urban, suburban, or rural according to the Eurostat Degree of Urbanization Tool. A logistic regression model was used to examine associations between the degree of urbanization and volunteer responder arrival before emergency medical services, cardiopulmonary resuscitation, or defibrillation. We found the odds for volunteer responder arrival before emergency medical services more than doubled in rural areas (odds ratio [OR], 2.60 [95% CI, 1.91–3.53]) and suburban areas (OR, 2.05 [95% CI, 1.56–2.69]) compared with urban areas. In OHCA cases where volunteer responders arrived first, odds for bystander cardiopulmonary resuscitation was tripled in rural areas (OR, 3.83 [95% CI, 1.64–8.93]) and doubled in suburban areas (OR, 2.27 [95% CI, 1.17–4.41]) compared with urban areas. Bystander defibrillation was more common in suburban areas (OR, 1.53 [95% CI, 1.02–2.31]), where almost 1 out of 4 patients received bystander defibrillation, compared with urban areas.

Conclusions
Volunteer responders are significantly more likely to arrive before emergency medical services in rural and suburban areas than in urban areas. Patients with OHCA received more cardiopulmonary resuscitation in rural and suburban areas and more defibrillation in suburban areas than in urban areas.
Association of Bovine Arch Anatomy With Incident Stroke After Transcatheter Aortic Valve Replacement
Authors: Lo Russo Gerardo V. , Alarouri Hasan S. , Al‐Abcha Abdulah , Vogl Brennan , Mahayni Abdulah , Sularz Agata , Hatoum Hoda , Collins Jeremy , Crestanello Juan A. , Alkhouli Mohamad 
Published: February 2024

Background
Acute ischemic stroke complicates 2% to 3% of transcatheter aortic valve replacements (TAVRs). This study aimed to identify the aortic anatomic correlates in patients after TAVR stroke.

Methods and Results

This is a single‐center, retrospective study of patients who underwent TAVR at the Mayo Clinic between 2012 and 2022. The aortic arch morphology was determined via a manual review of the pre‐TAVR computed tomography images. An “a priori” approach was used to select the covariates for the following: (1) the logistic regression model assessing the association between a bovine arch and periprocedural stroke (defined as stroke within 7 days after TAVR); and (2) the Cox proportional hazards regression model assessing the association between a bovine arch and long‐term stroke after TAVR. A total of 2775 patients were included (59.6% men; 97.8% White race; mean±SD age, 79.3±8.4 years), of whom 495 (17.8%) had a bovine arch morphology. Fifty‐seven patients (1.7%) experienced a periprocedural stroke. The incidence of acute stroke was significantly higher among patients with a bovine arch compared with those with a nonbovine arch (3.6% versus 1.7%;
P
=0.01). After adjustment, a bovine arch was independently associated with increased periprocedural strokes (adjusted odds ratio, 2.16 [95% CI, 1.22–3.83]). At a median follow‐up of 2.7 years, the overall incidence of post‐TAVR stroke was 6.0% and was significantly higher in patients with a bovine arch even after adjusting for potential confounders (10.5% versus 5.0%; adjusted hazard ratio, 2.11 [95% CI, 1.51–2.93];
P
<0.001).

Conclusions
A bovine arch anatomy is associated with a significantly higher risk of periprocedural and long‐term stroke after TAVR.
The Use of Pronoun Interpretation Biases in L1 Spanish: The Role of Language Proficiency, Exposure, and Use in Heritage Speakers
Authors: Contemori Carla , Mossman Sabrina , Armendariz Galaviz Alma L. 
Published: February 2024

Abstract
In an offline sentence comprehension task, we test the interpretation biases for null and overt pronouns and anaphoric and cataphoric pronouns in heritage speakers (HSs) whose first language (L1) is Spanish (L2 English). Previous studies have shown that Spanish HSs can interpret overt anaphoric pronouns differently than monolingual speakers. A question that remains unexplored is how HSs interpret cataphoric pronouns and how L1 experience affects pronoun resolution biases in these individuals. We recruited 48 HSs and 48 monolingual Spanish speakers. The results show that pronoun interpretation in HSs differs from monolingual biases, with HSs demonstrating a higher subject antecedent preference for anaphoric and cataphoric pronouns. The results further show that a continuous measure of language proficiency, exposure, and use may contribute to explaining pronoun interpretation biases in heritage Spanish. We discuss the findings in light of recent research demonstrating that language experience can contribute to shape discourse patterns.
A taxonomic update on Tylenchorhynchus annulatus (Nematoda: Dolichodoridae), a widely distributed stunt nematode species
Authors: Singh Phougeishangbam Rolish , Hajihassani Abolfazl 
Published: February 2024

Summary
The stunt nematode species, Tylenchorhynchus annulatus (Cassidy, 1930) Golden, 1971, is a widely distributed plant parasite found associated with various major agricultural crops. In the current work, a population of T. annulatus detected from a sugarcane field in Everglades, Florida, USA, was morphologically and molecularly characterised. A comparative study was also done including the stunt nematode populations identified morphologically and molecularly by different research groups as T. agri, T. annulatus or T. crassicaudatus from China, Indonesia, Iran, Korea, Niger, Nigeria, Tanzania and the USA, revealing highly similar morphology and overlapping morphometric data among the populations. However, these populations were found separated into two maximally supported clades in phylogenetic trees based on rRNA gene sequences (28S and ITS). One clade comprised populations from China, Indonesia, Iran, Nigeria, South Korea, Tanzania and the USA, and the other clade only populations from the USA. This study also strongly supported the view that T. crassicaudatus is a junior synonym of T. annulatus.
Wolfdietrichs Wurm
Authors: Schürr Diether 
Published: February 2024

Abstract
The MHG epic ‘Wolfdietrich’ and the ON ‘Thidreks saga’ contain an unlucky fight against a dragon: Wolfdietrich or Thidrek af Bern helps a lion against it, but the dragon takes the lion in its mouth and the knight in its tail and drags them to its cave. This very characteristic situation was depicted in medieval church art, at least three times: 1. on floor-tiles found in the monastery of Pilis (Hungary), including the sword broken into three pieces and three dragon cubs (13th century or roughly around 1300); 2. in the cloister of St. Michael at Hildesheim (Lower Saxony), together with a second dragon (1230/50); 3. on the richly decorated ‘Schottenportal’ of St. James at Regensburg (Bavaria), left side (second half of the 13th century). The last depiction is therefore older than the different versions of the MHG epic and the compilation of the ON saga, probably attesting that the unlucky dragon fight was already a part of a pre-literary ‘Wolfdietrich’.
Addressing the Association Between Action Video Game Playing Experience and Visual Search in Naturalistic Multisensory Scenes
Authors: Hamzeloo Mohammad , Kvasova Daria , Soto-Faraco Salvador 
Published: February 2024

Abstract
Prior studies investigating the effects of routine action video game play have demonstrated improvements in a variety of cognitive processes, including improvements in attentional tasks. However, there is little evidence indicating that the cognitive benefits of playing action video games generalize from simplified unisensory stimuli to multisensory scenes — a fundamental characteristic of natural, everyday life environments. The present study addressed if video game experience has an impact on crossmodal congruency effects when searching through such multisensory scenes. We compared the performance of action video game players (AVGPs) and non-video game players (NVGPs) on a visual search task for objects embedded in video clips of realistic scenes. We conducted two identical online experiments with gender-balanced samples, for a total of . Overall, the data replicated previous findings reporting search benefits when visual targets were accompanied by semantically congruent auditory events, compared to neutral or incongruent ones. However, according to the results, AVGPs did not consistently outperform NVGPs in the overall search task, nor did they use multisensory cues more efficiently than NVGPs. Exploratory analyses with self-reported gender as a variable revealed a potential difference in response strategy between experienced male and female AVGPs when dealing with crossmodal cues. These findings suggest that the generalization of the advantage of AVG experience to realistic, crossmodal situations should be made with caution and considering gender-related issues.
Observational Evidence for a Regime Shift in Summer Antarctic Sea Ice
Authors: Hobbs Will , Spence Paul , Meyer Amelie , Schroeter Serena , Fraser Alexander D. , Reid Philip , Tian Tian R. , Wang Zhaohui , Liniger Guillaume , Doddridge Edward W. , Boyd Philip W. 
Published: February 2024

Abstract
In recent years, the Southern Ocean has experienced extremely low sea ice cover in multiple summers. These low events were preceded by a multidecadal positive trend that culminated in record high ice coverage in 2014. This abrupt transition has led some authors to suggest that Antarctic sea ice has undergone a regime shift. In this study we analyze the satellite sea ice record and atmospheric reanalyses to assess the evidence for such a shift. We find that the standard deviation of the summer sea ice record has doubled from 0.31 million km2 in 1979–2006 to 0.76 million km2 for 2007–22. This increased variance is accompanied by a longer season-to-season sea ice memory. The atmosphere is the primary driver of Antarctic sea ice variability, but using a linear predictive model we show that sea ice changes cannot be explained by the atmosphere alone. Identifying whether a regime shift has occurred is difficult without a complete understanding of the physical mechanism of change. However, the statistical changes that we demonstrate (i.e., increased variance and autocorrelation, and a changed response to atmospheric forcing), as well as the increased spatial coherence noted by previous research, are indicators based on dynamical systems theory of an abrupt critical transition. Thus, our analysis is further evidence in support of a changed Antarctic sea ice system.

Significance Statement
In recent years, there have been several summers with extremely low Antarctic sea ice cover, including consecutive record lows in February 2022 and February 2023. Since then, the 2023 winter has seen a remarkably low sea ice growth with an anomaly far below expected climatology. This has led researchers to question whether there has been a regime shift, and we assess the observational evidence for such a shift. In the last decade or so, the variability of summer sea ice has almost doubled, accompanied by a much longer sea ice memory from season to season. These statistical changes, as well an increased spatial coherence noted by other researchers, are consistent with theoretical indicators of a critical transition, or regime shift.
Intensified Impact of Spring Tibetan Plateau Snow Cover on Summer Compound Heat Waves in Western Europe after 1998
Authors: Dong Wei , Jia XiaoJing , Wu Renguang 
Published: February 2024

Abstract
This study revealed a significant interdecadal change in the impact of spring western Tibetan Plateau (TP) snow cover (TPSC) on subsequent summer compound heat waves (CHWs) in western Europe (WE) after 1998. This interdecadal change is attributed to a change in a western Europe high–western TP low (WEH–TPL) atmospheric circulation pattern. This pattern arises due to both the inherent variability of TPSC and the phase transition of the Atlantic multidecadal oscillation (AMO) after 1998. The increased magnitude and persistence of western TPSC from spring to summer after 1998 enhanced the snow–atmosphere coupling effect, intensifying ascent and decent motion over the TP and WE, respectively, and strengthening the WEH–TPL pattern. In addition, the post-1998 positive AMO phase favors continuous and stable downstream Rossby wave propagation, enhancing the WEH–TPL pattern and the TPSC–CHWs relationship. Further analyses reveal that the interdecadal changes in the TPSC and the AMO around 1998 contribute to the presence of “double jets” over the North Atlantic–central Eurasian sectors. The TPSC–related anomalous atmospheric circulation and AMO phase shift contribute to the southern and northern branches of the intensified westerly jet, respectively. These conditions create a favorable environment for the formation and persistence of summer CHWs in WE. Numerical modeling experiments with a linear baroclinic model confirm these findings. Our findings suggest that in the context of a changing climate, TPSC plays a pivotal role in the genesis of summer CHWs in WE and may serve as a valuable predictor for CHWs.

Significance Statement
This study discovered that starting from 1998 there was a significant change in how spring snow cover on the western Tibetan Plateau affects summer compound heat waves in western Europe. After 1998, the snow cover on the western Tibetan Plateau increased in size and lasted longer from spring to summer, intensifying the interaction between the snow and the atmosphere. This led to more rising and sinking air over the Tibetan Plateau and western Europe, respectively. Also, after 1998 a positive phase of the Atlantic multidecadal oscillation (AMO) was favorable for the circulation connection between western Europe and the Tibetan Plateau. Further analysis showed that these changes in snow cover and the AMO after 1998 caused “double jets” in the North Atlantic and central Eurasia that created better conditions for summer heat waves in western Europe. Numerical models are used to confirm these findings. Our research indicates that, in a changing climate, the snow cover on the western Tibetan Plateau plays a crucial role in the development of summer heat waves in western Europe and can be a useful predictor for these heat waves.
Diurnal Warm Layers in the Ocean: Energetics, Nondimensional Scaling, and Parameterization
Authors: Schmitt M. , Pham H. T. , Sarkar S. , Klingbeil K. , Umlauf L. 
Published: February 2024

Abstract
Diurnal warm layers (DWLs) form near the surface of the ocean on days with strong solar radiation, weak to moderate winds, and small surface-wave effects. Here, we use idealized second-moment turbulence modeling, validated with large-eddy simulations (LES), to study the properties, dynamics, and energetics of DWLs across the entire physically relevant parameter space. Both types of models include representations of Langmuir turbulence (LT). We find that LT only slightly modifies DWL thicknesses and other bulk parameters under equilibrium wave conditions, but leads to a strong reduction in surface temperature and velocity with possible implications for air–sea coupling. Comparing tropical and the less frequently studied high-latitude DWLs, we find that LT has a strong impact on the energy budget and that rotation at high latitudes strongly modifies the DWL energetics, suppressing net energy turnover and entrainment. We identify the key nondimensional parameters for DWL evolution and find that the scaling relations of Price et al. provide a reliable representation of the DWL bulk properties across a wide parameter space, including high-latitude DWLs. We present different sets of revised model coefficients that include the deepening of the DWL due to LT and other aspects of our more advanced turbulence model to describe DWL properties at midday and during the DWL temperature peak in the afternoon, which we find to occur around 1500–1630 local time for a broad range of parameters.