bluuebunny/crossref_metadata_2025_split huggingface dataset:
Secondary hyperparathyroidism: Diagnosis of site of recurrence
Authors: Casanova Daniel , Sarfati Emile , De Francisco Angel , Amado J. Antonio , Arias Manuel , Dubost Claude 
Published: May 2005

AbstractPersistent or recurrent hyperparathyroidism after total parathyroidectomy with forearm implant may be caused by hyperplastic grafted tissue, residual parathyroid tissue left in the neck or the presence of a supernumerary gland not found during surgery. A correct assessment of graft function is needed to localize the source of hormone excess and to avoid an unnecessary neck reoperation in cases of graft dependent hyperparathyroidism. In 12 patients with relapsing hyperparathyroidism after total parathyroidectomy with forearm implant, total ischemic blockade of the arm bearing the parathyroid graft produced a “transitory implantectomy” with a significant reduction of serum levels of intact PTH in those with graft hyperfunction. In 6 patients with proved supernumerary glands, total ischemia of the graft was not followed by significant changes in intact PTH. Hyperparathyroidism was reversed after surgical resection of the parathyroid implants in the 6 patients with positive responses to the ischemic maneuver. A repeat neck reoperation removing cervical or mediastinal supernumerary glands was followed by control of recurrent hyperparathyroidism in the 6 patients with a negative response to the ischemic blockade. Total ischemic blockade of the arm bearing the parathyroid graft is a valuable new method for a correct assessment of graft function after total parathyroidectomy with forearm autotransplantation.
Use of Ligasure in Thyroidectomy Procedures: Results of a Prospective Comparative Study
Authors: Kirdak Turkay , Korun Nusret , Ozguc Halil 
Published: May 2005

AbstractThe thyroidectomy procedure requires many manupulations to achieve prompt hemostasis. This study assessed whether the outcomes of thyroidectomy using the Ligasure electrothermal vessel sealer were comparable with the conventional suture‐ligation technique. We prospectively evaluated 58 consecutive patients who underwent thyroidectomy. Patients were allocated into two groups according to their preference. There were 30 patients in the Ligasure group and 28 patients in the conventional surgery group. Complications, operating time, and hospital stay were compared between the two groups and suture‐ligations performed in the Ligasure group were recorded. The age, sex, and indications were similar in the two groups (p > 0.05). Complication rates and hospital stays did not show any difference according to the techniques used. Operating time was shorter in the hemithyroidectomy and total thyroidectomy patients of the Ligasure group (mean ± SD: 77.38 ± 13.71 vs. 99.80 ± 12.53 minutes, p = 0.005; and 102.50 ± 16.69 vs.128.89 ± 19.74 minutes, p = 0.010). The mean ± SD number of suture‐ligations for each patient in the Ligasure group was 1.83 ± 2.12. Thyroid surgery using the Ligasure is safe, and its complication rates are comparable to these found with the conventional surgical technique. Use of the Ligasure during hemithyroidectomy and total tyhroidectomy operations provides a significantly shorter operating time.
Introducing the Cardibra: A Randomised Pilot Study of a Purpose Designed Support Bra for Women Having Cardiac Surgery
Authors: Naismith Carolyn , Street Annette 
Published: May 2005

Background: Cardiac nurses instruct women to wear a brassiere (bra) after a sternotomy for cardiac surgery to reduce lateral tension on the wound. However this practice is rarely implemented because regular bras impede nursing care in the immediate postoperative period. The Cardibra was developed to address the inadequacies of the regular bra and provide an alternate method of breast support. Aim: To develop a purpose designed support bra (the Cardibra) and evaluate its effectiveness on sternal wound healing and the reduction of pain for women who had a sternotomy for cardiac surgery. Methods: The study consisted of two stages. Stage 1 described the development of the Cardibra. Stage 2 was a pilot study of a clinical trial, prospective, randomised two-group design. The treatment group consisted of 10 women using the Cardibra immediately following surgery and the control group of 10 who wore a regular bra 3 days post surgery. Repeated measures at six time points assessed pain levels and wound healing. Results: This study indicated that the Cardibra might have beneficial therapeutic effects on pain levels and wound healing up to day 14 after cardiac surgery. Conclusion: This innovative device may offer therapeutic benefits to women following cardiac surgery.
Obstructive sleep apnea and head and neck neoplasms
Authors: Rada Roy 
Published: May 2005

OBJECTIVETo elaborate the relationship between obstructive sleep apnea (OSA) and head and neck neoplasms (HNN).STUDY DESIGN AND SETTINGA systematic review of the MEDLINE literature.RESULTSThirty of 34 articles indexed under OSA and HNN were about neoplasms that presented first as OSA. Four of the articles were about treatment of HNN causing OSA and gave incidences varying from 8% to 92%. Quality of life surveys confirm that patients with malignant HNN have sleep problems. Xerostomia may contribute to these sleep problems, and the role of salivary mucins deserves consideration.CONCLUSIONSThis review of the literature raises several new research questions about the clinical and biological relationships between OSA and HNN. (Otolaryngol Head Neck Surg 2005;132:794‐9.)
Seldinger‐assisted videotelescopic intubation (SAVI): A common sense approach to the difficult pediatric airway
Authors: Michaelson Peter G. , Mairy Eric A. 
Published: May 2005

OBJECTIVESTo describe the Seldinger‐assisted videotelescopic intubation (SAVI) technique, a complementary method for aiding in difficult pedi‐atric intubations that uses common equipment available to the practicing otolaryngologist.STUDY DESIGNTechnique description.METHODSDetailed description of technique for use of a pediatric laryngoscope with video‐assisted endotracheal tube (ETT) covered rigid tracheoscopy controlled intubation in difficult pediatric airways.RESULTSIn our practice, SAVI is vital in establishing a secure airway in the difficult‐to‐intubate child. After insertion of a laryngoscope, an appropriate sized endotracheal tube is delivered through the glottis under direct video‐visualization from a rigid telescope using a variation of the well‐established Seldinger technique. The telescope serves as the stable ETT stylet that also provides panoramic visualization. The ETT slides over the telescope to provide a secure airway directly visible to all in the operating room. Benefits of the SAVI technique to previously described video‐assisted intubations with flexible or specially designed endoscope devices include decreased cost, employment of previously existing endoscopy skills, the benefit of rigid delivery of the endotracheal tube as well as innate versatility to a multitude of clinical situations.CONCLUSIONSThe SAVI technique offers an additional practical clinical solution to the difficult pediatric airway. Although ultimately establishing the airway depends on the skills of the operator, the SAVI technique has saved multiple lives by using common equipment through a common‐sense approach. EBM rating: D. (Otolaryngol Head Neck Surg 2005;132:677‐680.)
Long‐term histological outcomes of injected autologous fat into human vocal folds after secondary laryngectomy
Authors: Sasai Hisanori , Watanabe Yusuke , Muta Hiroshi , Yoshida Junichi , Hayashi Ibuki , Ogawa Makoto , Kubo Takeshi 
Published: May 2005

OBJECTIVETo histologically evaluate the long‐term outcomes of autologous fat grafts after injection laryngoplasty in the human larynx.STUDY DESIGN AND SETTINGWe injected liposuctioned fat for vocal fold augmentation in patients with vocal fold paralysis. We suctioned autologous fat from the low abdomen with an 18‐G disposable needle and a 20‐mL disposable syringe under negative pressure. This is different from the conventional liposuction technique and avoids the use of special equipment. In this article, we report the histological evaluation of 2 patients (patient 1: 12 months, patient 2: 41 months) who required total laryngectomy after autologous fat injection into the vocal folds.RESULTSHistological examination revealed normal‐appearing viable adipocytes with minimal inflammatory response in both patients.CONCLUSIONSOur liposuctioned autologous fat injection histologically offered long‐term improvement in patients with impaired glottal closure from vocal fold paralysis. (Otolaryngol Head Neck Surg 2005;132:685‐688.)
Trends in the diagnosis and the management of Meniere's disease: Results of a survey
Authors: Kim Harold H. , Wiet Richard J. , Battista Robert A. 
Published: May 2005

OBJECTIVETo determine the practices of the American Neurotology Society (ANS) membership in the evaluation and treatment of the Meniere's patient.STUDY DESIGNProspective.INTERVENTIONQuestionnaire.MAIN OUTCOME MEASURERespondents’ response to questions pertaining to the diagnostic and therapeutic practices in the management of Meniere's disease.RESULTSThree hundred members of ANS were mailed a 15‐item questionnaire. Two hundred three responded, for a 67.7% response rate. For the diagnosis of Meniere's disease, 1 in 3 practitioners relied solely on history, physical exam, and audiometry, whereas 2 in 3 relied in part on adjunctive tests, such as electrocochleography (ECOG) and electronystagmography (ENG). Two in 3 practitioners pursued retrocochlear studies on initial evaluation, with the overwhelming majority using MRI. In treating Meniere's disease, conservative medical management was preferred. For medically recalcitrant Meniere's disease, endolymphatic sac surgery (ESS) was the most commonly employed initial intervention (50%), followed by transtympanic gentamicin (38%). Currently, <10% routinely recommend the Meniett device. Eighty‐three percent include ESS as a therapeutic option for medically recalcitrant Meniere's disease. The vast majority continue to perform surgical labyrinthectomies and vestibular nerve sections for Meniere's disease.CONCLUSIONSMeniere's disease continues to pose a difficult diagnostic and therapeutic problem, resulting in heterogeneous approaches to both evaluation and treatment. Despite the 1995 American Academy of Otolaryngology guidelines in the diagnosis of Meniere's disease, most clinicians rely in part on ENG or ECOG in diagnosing Meniere's disease. Furthermore, despite the passing of 20 years since the publications claiming a purely placebo effect, ESS is the most commonly employed initial surgical treatment for Meniere's disease. (Otolaryngol Head Neck Surg 2005;132: 722‐6.)
Tumor‐dendritic cell fusion as a basis for cancer immunotherapy
Authors: Lee Walter T. , Shimizu Keiji , Kuriyama Hide , Tanaka Hiro , Kjaergaard Jorgen , Shu Suyu 
Published: May 2005

OBJECTIVETo establish the basis for use of allogeneic dendritic‐tumor fusion cells.STUDY DESIGNFusion cells were created by electrofusion. We used 2 allogeneic murine tumor lines (D5 and 4T1) that were virally transduced to express the antigen (β‐galactosidase) as a surrogate tumor marker.RESULTSCross‐immunization was achieved with irradiated allogenic tumor cells. Successful electrofusion of dendritic cells and tumor cells was confirmed by using fluorescence‐activated cell sorting and cytospin. Significant responses were shown in immunized mice against tumor challenge and established 3‐day pulmonary metastasis with fusion cells.CONCLUSIONSAllogeneic tumor sharing a common tumor antigen can immunize against syngeneic tumor challenge. Fusion cells showed successful immunization against tumor challenge and showed regression of 3‐day established pulmonary metastasis.SIGNIFICANCEThese preclinical studies provide evidence that an allogenic tumor‐dendritic cell fusion vaccine is a valid approach for head and neck cancer immunotherapy. (Otolaryngol Head Neck Surg 2005;132:755‐64.)
Oncologic and functional results of supracricoid partial laryngectomy with cricohyoidopexy
Authors: Akbas Yucel , Demireller Alp 
Published: May 2005

OBJECTIVESupracricoid partial laryngectomy with cricohyoidopexy (SPL‐CHP) is an alternative technique described for extensive tumors of the larynx that are beyond the limits of classical conservation partial laryngectomy and otherwise would be treated by total laryngectomy.STUDY DESIGN AND SETTINGForty‐six patients with carcinoma of the larynx underwent SPL‐CHP between 1991 and 2003. The median age was 54 (range, 37 to 72). In 28 cases both arytenoids were spared; in 17 cases, 1 arytenoid was spared; and in 1 case, 2 arytenoids were resected. Bilateral elective neck dissections were performed in supraglottic carcinomas. In glottic carcinomas, neck dissection was performed in the presence of clinically positive lymph nodes. None of the patients were treated with postoperative radiation therapy.RESULTSForty‐five patients were successfully decannulated; 1 patient with 2 arytenoids resected could not tolerate decannulation. The mean time for decannulation was 20 days (range, 9 to 60 days) when both arytenoids were spared with SPL‐CHP, and 41 days (range, 13 to 150 days) for SPL‐CHP when 1 arytenoid was spared. The average time for removal of the feeding tube was 21 days (range, 9 to 60 days) when both arytenoids were spared, and 40 days (range, 16 to 127 days) when 1 arytenoid was spared. The removal time of the feeding tube of the patient with 2 arytenoids resected was postoperative day 63. In 2 patients, aspiration pneumonia occurred as a result of swallowing impairment. In none of the patients temporary or permanent gastrostomy was needed. Two patients had local recurrence and were treated with a total laryngectomy; they are still alive. In 2 patients, secondary primary tumors were detected. The 3‐year overall and cause‐specific actuarial survival rates were 95.7% and 87.5%, respectively.CONCLUSIONSAlthough prolonged hospitalization and delaying physiological functions can be termed as disadvantages of SPL‐CHP, the operation is a reliable and oncologically valid procedure in selected cases of cancer of the larynx who would otherwise be operated by total laryngectomy.
Tracheal wall for the reconstruction of extended hemilaryngectomy in the rabbit model
Authors: Brandariz Jose Antonio , Grau Monserrat 
Published: May 2005

OBJECTIVETo evaluate reconstruction of the surgical wound of extended hemilaryngectomy using the tracheal wall.STUDY DESIGN AND SETTINGProspective, nonrandomized experimental study in a rabbit model in which cricothyroid hemilaryngectomy was performed in 10 rabbits. The proximal trachea was tailored to cover the surgical wound and sutured to it. The ipsilateral lobe of the thyroid gland and the medial thyroid vascular pedicle were conserved so as to assure vascular supply to the tracheal flap. After 4 weeks the animals were sacrificed and pathology analysis conducted.RESULTSEight of the 10 rabbits survived without respiratory or deglutitory alterations. Pathologic analysis showed well‐healed suture lines together with normal mucosa and cartilage rings in the tracheal flap.CONCLUSIONSThe tracheal wall appears to be the ideal donor tissue for repair of the larynx.SIGNIFICANCEThis simple, 1‐session surgical procedure demonstrates an effective reconstruction of an extended hemilaryngectomy wound.
Evaluation of tumor oxygenation by color duplex sonography: A new approach
Authors: Martino Ercole F.N. Di , Gagel Bernd , Schramm Oliver , Maneschi Payam , Westhofen Martin 
Published: May 2005

OBJECTIVEDescription of a new noninvasive method for the evaluation of tissue oxygenation in head and neck cancer.STUDY DESIGN AND SETTINGProspective nonrandomized controlled study in an academic medical center on 20 patients with neck metastases of head and neck cancer. Metastases were investigated using color duplex sonography and pO2 histography. The vascularization in sonography was quantitatively evaluated by color pixel density and compared to the pO2 values of the same nodes.RESULTSThe correlation between vascularization and flow velocity was 0.71. For the mean/median pO2‐values and for the pO2 readings < 10.0 mmHg correlations were r = 0.65/0.76 and 0.71.CONCLUSIONThis sonographic method allows a safe and reliable evaluation of oxygenation in metastases of head and neck cancer.SIGNIFICANCEThe new approach is an alternative to pO2 histography and may play a future role in the planning of radiotherapy in the neck. (Otolaryngol Head Neck Surg 2005;132:765‐9.)
Four cases of simultaneous triple primary cancers of the hypopharynx, esophagus, and stomach
Authors: Ikeda Yoichi , Tsukuda Mamoru , Ishitoya Junichi , Arai Yasuhiro , Matsuda Hideki , Katori Hideaki , Taguchi Takahide , Yoshida Takafumi , Ono Machiko , Sakuma Yasunori , Yagisawa Mizuho , Saito Norifumi 
Published: May 2005

OBJECTIVETo study the efficacy of intensive chemotherapy for simultaneous triple primary cancers of the hypopharynx, esophagus, and stomach.STUDY DESIGNRetrospective case study.METHODSFrom April 2000 to March 2002, we treated 4 patients who had simultaneous triple primary cancers, including hypopharyngeal, esophageal, and gastric carcinomas. These 4 patients were designated as the objects for analysis, and the treatment modality for simultaneous multiple primary cancer cases was examined.RESULTSIn 3 of 4 patients, all 3 primary cancers could be controlled by intensive induction chemotherapy and concurrent chemoradiotherapy for hypopharyngeal cancer and by endoscopic mucosal resection or argon plasma coagulation for esophageal and gastric carcinomas.CONCLUSIONSIn the treatment modality for simultaneous multiple primary cancers, including head and neck cancer, it is important to select intensive systemic chemotherapy and decide the order for treating each primary lesion in consideration of each patient's curability and prognosis. (Otolaryngol Head Neck Surg 2005;132:788‐93.)
Intrinsic laryngeal muscle reinnervation with nerve‐muscle pedicle
Authors: Tóth Andrea , Szócs Attila , Harasztosi Csaba , Matesz Klára , Pucsok Klára , Mikó Irén , Sziklai István 
Published: May 2005

OBJECTIVETo test the application of the nerve‐muscle pedicle (NMP) technique for selective rein‐nervation of previously denervated posterior cricoarytenoid (PCA) muscle.METHODSThe left recurrent laryngeal nerve (RLN) was severed in 5 mongrel dogs, and an ansa cervicalis‐sternohyoid muscle pedicle was sutured to the left PCA muscle. Three dogs underwent a sham operation. Videolaryngoscopy was performed, and electromyographic data were collected after 1 year on average. Finally, histologic analysis of the NMP was performed.RESULTSThe video records showed the return of mobility of the PCA muscle reinnervated by the NMP. EMG data as to show evoked polyphasic potentials showed also evidence of reinnervation of the PCA muscle. With immunohistochemical reaction (antineurofilament antibody+biotin) we could show neurofilaments and motor endplates in both sides in all 5 animals.CONCLUSIONSThe NMP technique could eliminate the need for arytenoidectomy and laterofixation in patients with unilateral or bilateral vocal fold paralysis. The quality of life and voice may be improved. (Otolaryngol Head Neck Surg 2005;132:701‐6.)
The “pull‐back” technique for Nucleus 24 perimodiolar electrode insertion
Authors: Todt Ingo , Basta Dietmar , Eisenschenk Andreas , Ernst Arne 
Published: May 2005

OBJECTIVETo observe the influence of electrode pull‐back after cochlear implant insertion of Nucleus 24 perimodiolar electrodes.STUDY DESIGNIn a prospective intraoperative study, we analyzed the impedances, neural response telemetry responses, and the spread of excitation after cochlear implant electrode insertion and compared these data to those obtained after a subsequent, controlled pull‐back of the electrode. Postoperative depth of electrode insertion was controlled by x‐ray.SETTINGTertiary referral center.SUBJECTSSix patients (4 male, 2 female; 18 to 69 years) were implanted with a Nucleus 24 (RCA) cochlear implant with a perimodiolar electrode.RESULTSAfter a controlled pull‐back, a significant decrease of the spread of excitation at the stimuli electrodes 5, 10, 15, and a nonsignificant decrease at stimuli electrode 20 compared to the recordings after the primary normal insertion procedure was found. The mean electric compound action potential amplitude was increased with an apical‐to‐basal tendency. Impedances remained unchanged by the pull‐back. Mean insertion depth at the postoperative x‐ray control was 372 degrees (± 10.2).CONCLUSIONControlled cochlear implant electrode pull‐back is a novel technique that optimizes objective intraoperative electrophysiological recordings in patients implanted with a Nucleus 24 perimodiolar cochlear implant by a greater approximation of the electrode to the modiolus. (Otolaryngol Head Neck Surg 2005;132:751‐4.)
Psychosocial rehabilitation and psychiatry in the treatment of schizophrenia — what are the boundaries?
Authors: Leona  , Bachrach L. 
Published: May 2005

Objective: To examine the relationship between psychosocial rehabilitation and psychiatry with particular emphasis upon treatment of people who suffer from schizophrenia. Method: Current literature is examined in an effort to identify prevailing premises and myths held by each discipline as it relates to the other. Results: A working definition of psychosocial rehabilitation is proposed, and nine interrelated concepts that constitute the belief system of that discipline are identified. Conclusion: Rehabilitation's biopsychosocial perspective provides a strong basis for joint enterprise with psychiatry in the care of people with schizophrenia. However, members of both disciplines must pursue active measures in order to effect co‐operative treatment interventions.
Models of community treatments in schizophrenia: do they travel?
Authors: Burns Tom 
Published: May 2005

Objective: To explore the stability of conclusions from mental health services research across differing care systems. Contradictory results in different countries for similar studies of programmes for patients with schizophrenia have usually been attributed to poor replication. This paper explores whether these differing results can illuminate aspects of schizophrenia by examining the interaction of the disorder with the care context as an alternative explanation. Method: The findings of a large UK random controlled trial of intensive case management with such patients is compared to previous UK and US studies. Results: Reduction of case‐load size of psychotic patients did not significantly reduce their need for hospitalization in the context of locally available co‐ordinated care. Conclusion: There is more to be gained in understanding complex disorders such as schizophrenia by interpreting the impact of context on treatment study outcomes than by simply dismissing contradictory findings as failures of implementation of either research or clinical practice.
Public acceptance of restrictions on mentally ill people
Authors: Lauber C. , Nordt C. , Falcato L. , Rössler W. 
Published: May 2005

Objective: To assess the influence of demographic, psychological, sociological and cultural variables on the public acceptance of restrictions on mentally ill people. Method: Multiple logistic regression analysis of the results of an opinion survey conducted on a representative sample in the German, French and Italian‐speaking part of Switzerland. Results: Public acceptance of restrictions depends on age, education and gender. The influence of demographic variables is reduced when including rigidity, anomie, social distance and contact with mentally ill people in the analysis. The cultural influence of the language region is significant. All these factors predict acceptance. Stereotypes and emotional reactions have no influence. Conclusion: Attitudes to mentally ill people are shaped on three distinct levels, the psychological, social and cultural, respectively. Demographic variables partly play the role of placeholders covering the underlying relationships.