bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global trends in research related to functional dyspepsia and anxiety or depression over the past two decades: a bibliometric analysis
Authors: Huang Qian , Yuan Huixiao , Li Qingqing , Li Yang , Geng Shasha , Zhu Yingqian , Liao Min , Jiang Hua 
Published: November 2023

Background and purposeFunctional dyspepsia (FD) is a prevalent global disorder of the upper digestive tract characterized by functional impairment. It often coexists with anxiety/depression, significantly impairing occupational productivity and overall quality of life. This study aimed to identify emerging patterns and prominent themes within FD and anxiety/depression research through bibliometric analysis to help explore new innovative avenues for investigating this type of FD.MethodsA comprehensive review of literature encompassing FD and anxiety/depression was conducted using the Science Citation Index Extension of the Web of Science Core Collection from 2003 to 2023. Information extracted comprised “Full Record and Cited References.” Bibliometric analysis of relevant publications, including country, institution, author, journal, citations, and keywords, was conducted using CiteSpace, VOSviewer, and Bibliometrix package in R and Excel.ResultsStudies related to FD and anxiety/depression have demonstrated an ascending trajectory since 2003. Our bibliometric analysis identified 338 studies published by 2023. NEUROGASTROENTEROLOGY AND MOTILITY emerged as the most prolific journal, while GASTROENTEROLOGY retained pre-eminence within the top 10 published journals. China emerged as the most prolific country, with two institutions within the top 10 in terms of volume of publications. The Mayo Clinic stood as the foremost institution in terms of publication volume, with the Chengdu University of Traditional Chinese Medicine exhibiting robust collaborative engagement. Eminent author influence was attributed to Talley NJ of Newcastle University, Australia. Clusters of extensively cited papers and prevalent keywords delineate the status and trend of FD and anxiety/depression research. This encompasses FD, anxiety, depression, sleep disorders, and functional gastrointestinal disorders. Furthermore, the timeline view map or trend-term analysis suggested that duodenal low-grade inflammation (“duodenal eosinophilia” and “mast cells”) might be a new concern associated with FD and anxiety/depression.ConclusionEmploying bibliometric analysis, this study revealed prevalent focal areas and new trends within FD and anxiety/depression research. These insights serve as valuable guidance for scholars seeking to delve into new research avenues.
Chemical characterization and metabolic profiling of Xiao-Er-An-Shen Decoction by UPLC-QTOF/MS
Authors: Yang Ruipei , Wei Lifang , Wang Jie , Huang Shiying , Mo Pingli , Chen Qiugu , Zheng Ping , Chen Jihang , Zhang Shangbin , Chen Jianping 
Published: November 2023

Background: Xiao-Er-An-Shen decoction (XEASD), a TCM formula composed of sixteen Chinese medicinal herbs, has been used to alleviate tic disorders (TD) in clinical practice for many years. However, the chemical basis underlying the therapeutic effects of XEASD in the treatment of TD remains unknown.Purpose: The present study aimed to determine the major chemical components of XEASD and its prototype compounds and metabolites in mice biological samples.Methods: The chemical constituents in XEASD were identified using ultra-high Performance liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry (UPLC-Q-TOF-MS/MS). Following this, XEASD was orally administered to mice, and samples of plasma, urine, feces, bile, and tissue were collected in order to identify effective compounds for the prevention or treatment of TD.Result: Of the total 184 compounds identified to be discriminated in the XEASD, comprising 44 flavonoids, 26 phenylpropanoids, 16 coumarins, 16 triterpenoids, 14 amino acids, 13 organic acids, 13 alkaloids, 13 ketones, 10 cyclic enol ether terpenes, 7 citrullines, 3 steroids, and 5 anthraquinones, and others. Furthermore, we summarized 54 prototype components and 78 metabolic products of XEASD, measured with biological samples, by estimating metabolic principal components, with four prototype compounds detected in plasma, 58 prototypes discriminated in urine, and 40 prototypes identified in feces. These results indicate that the Oroxylin A glucuronide from Citri reticulatae pericarpium (CRP) is a major compound with potential therapeutic effects identified in brain, while operating positive effect in inhibiting oxidative stress in vitro.Conclusion: In summary, our work delineates the chemical basis underlying the complexity of XEASD, providing insights into the therapeutic and metabolic pathways for TD. Various types of chemicals were explored in XEASD, including flavonoids, phenylpropanoids, coumarins, organic acids, triterpenoid saponins, and so on. This study can promote the further pharmacokinetic and pharmacological evaluation of XEASD.
Does obesity Kuznets curve exist in developing economies? Evidence from 38 African countries based on heterogeneous panel data analysis on income-level classification
Authors: Chen Hao , Atingabili Samuel , Mensah Isaac Adjei , Yaw Omari-Sasu Akoto , Agba Tackie Evelyn , Arboh Francisca , Danso Bertha Ada 
Published: November 2023

IntroductionThe global pandemic disease known as the obesity epidemic has spread throughout the planet. Particularly, Africa is facing a growing problem of obesity, and the trend is rising. This is a result of a ticking time bomb. Given the claim that multiple socio-economic factors significantly affect the diversity in obesity rates between nations, economic development can be seen as a key contributor to this variation.MethodsRelying on the aforementioned avowal, this extant research examines the relationship between obesity and economic growth using urbanization, trade openness, and unemployment as intermittent variables within the Obesity Kuznets Curve (OKC) framework. Using panel data from 1990 to 2020, a panel of 38 African countries subdivided into income levels (Low income, Lower-middle income, and Upper-middle income) were analyzed. With the presence of residual cross-sectional reliance and slope heterogeneity, the Augmented Mean Group (AMG) econometric approach is employed.ResultsKey outcomes from the mentioned estimation method unveiled that economic growth positively impacts obesity among all the study panels. Variably, unemployment was evidenced to have a palpable positive impact on obesity concerning Low-income economies whereas on the side of the Lower-middle income panel together with Upper-middle income economies and the aggregated panel, a significant negative relationship is observed with obesity. Further, urbanization enhanced obesity in the Low-income panel and the aggregated panel of African nations, whereas an adverse effect is identified in both the Lower-middle and Upper-middle economies in Africa. Moreover, except for Low-income African economies, all the other panels of African nations in terms of income levels were noted to have a significant negative effect on obesity from trade openness.DiscussionFinally, the long-run coefficients indicated that the OKC is valid among all panels of African countries. The study thus preferably suggests in African economies that addressing the inverted U-shape relationship between obesity and economic growth requires a multifaceted approach that considers the evolving dynamics of both factors. Policy makers should, therefore, aim to balance promoting economic growth and safeguarding public health through targeted interventions and long-term strategies.
Une enseignante s’initie à l’arabe dialectal
Authors: D. Geneviève , Charlot Martine 
Published: November 2023

Dans la mesure où les enseignants assurent une présence auprès des familles étrangères ne sont-ils pas des sortes de « travailleurs sociaux » ? C’est le cas de Geneviève D…, institutrice dans la région parisienne qui a consacré beaucoup de temps et d’argent à apprendre l’arabe dans des stages fréquentés surtout par des travailleurs sociaux. Elle explique pourquoi aux lecteurs de Migrants-Formation.
Analisis Sistem Pengendalian Internal Berbasis COSO Dalam Upaya Pencegahan Fraud (Studi Kasus di Bank Syariah Indonesia Kantor Branch Financing Operasion (BFO) Banyuwangi)
Authors: Ilham Moh. , Hafidh Ali Abd. 
Published: November 2023

Sistem pengendalian internal merupakan alat yang digunakan untuk dapat mengendalikan dan menggolongkan fungsi-fungsi dalam organisasi agar seluruh aktivitas yang ada dapat berjalan sesuai dengan perencanaan manajemen sehingga tujuan perusahaan bisa dicapai secara efektif dan efisien. Di Indonesia sendiri mengadopsi dari Committee of Sponsoring Organization of the Treadway Commsission (COSO) yang didirikan sebagai bentuk untuk melawan Fraud (kecurangan) yang marak terjadi.
Untuk kegiatan sehari-hari di kantor Branch financing operasional (BFO) Banyuwangi, memiliki kebijakan tersendiri melibatkan para peserta magang untuk membantu kegiatan operasional di kantor BFO. Apabila tidak di awasi dengan benar maka bisa menimbulkan adanya fraud yang tidak diinginkan, maka perlu adanya sistem pengendalian internal yuang baik di dalamnya agar fraud tidak terjadi.
Penelitian kualitatif deskriptif ini bertujuan untuk mengetahui sistem pengendalian internal yang dalam upaya pencegahan fraud di kantor Branch Financing Operations (BFO) menggunakan kerangka konsep COSO. Teknik pengumpulan data berupa observasi, wawancara, dan dokumentasi. Kemudian teknik pengolahan dan analisis data dilakukan dengan tiga tahap yaitu reduksi data, penyajian data dan verifikasi data atau penarikan kesimpulan.
Hasil penelitian ini menunjukkan bahwa Sistem pengendalian internal dalam upaya pencegahan fraud di Kantor BFO Banyuwangi menggunakan kerangka konsep COSO masih ada salah satu komponen yang belum sesuai, yaitu pada komponen aktivitas pengendalian. Karena pada proses pencegahan fraud di Kantor BFO Banyuwangi secara murni tidak hanya para staff yang menjalankan kegiatan operasionalnya namun masih ada campur tangan dari orang luar yaitu peserta magang. Hal ini kurang sesuai dengan aktivitas penegendalian dalam pemisahan tugas yang memadai.
The Relationship Between Sitting Duration And Flexibility Hamstring Muscle In Employees At RSUD Ngimbang
Authors: Wibowo Hardianto , Rahmanto Safun , Lubis Zidni 
Published: November 2023

Some employees at Ngimbang Hospital work activities are carried out in a sitting position for a long duration and almost done every day, especially for office administration employees. This will pose a risk of musculoskeletal disorders, especially hamstring muscle flexibility. A decrease in muscle flexibility will affect body fitness which can affect the work productivity of these employees. This study aims to determine the relationship between sitting duration and hamstring muscle flexibility.
This study used a Cross Sectional Study research design involving 32 employee samples. Sitting duration is the independent variable while the dependent variable is hamstring muscle flexibility.
The results of the normality test using the Shapiro-wilk test showed that the sitting duration variable was worth 0.000 and the hamstring muscle flexibility variable was worth 0.799, meaning that there was one variable that was not normally distributed, while the correlation test using Spearman obtained a value of 0.000 (<0.05). It is concluded that there is a relationship between sitting duration and hamstring muscle flexibility in employees at Ngimbang Hospital. The longer the duration of sitting, the more hamstring muscle flexibility decreases.
ANALYSIS OF FACTORS RELATED TO MIDWIFE CAREER DEVELOPMENT IN PUSKESMAS PLUS PERBAUNGAN, SERDANG BEDAGAI REGENCY
Authors: Sari Yunita , Barita Aritonang  , Rahmad Gurusinga  
Published: November 2023

Masalah kinerja sudah menjadi permasalahan yang serius bagi instansi manapun saat ini, dan kinerja yang baik tentunya menjamin kualitas pelayanan yang baik. Oleh karena itu, memberikan pelatihan dan pengembangan profesi kepada karyawan sangat penting untuk melaksanakan tujuan organisasi secara efektif dan efisien. Berdasarkan penelitian awal di Puskesmas Perbaungan Plus menunjukkan hambatan pengembangan profesi bidan, yaitu : Kurang optimalnya dukungan administratif, buruknya kinerja bidan, dan kurangnya bimbingan dalam pengembangan profesi. Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berhubungan dengan pengembangan profesi bidan di Puskesmas Pervaungan Plus Kabupaten Serdang Bedagai. Desain penelitian yang digunakan dalam penelitian ini adalah survei analitik dengan menggunakan studi cross-sectional. Populasi penelitian seluruhnya terdiri dari bidan dan berjumlah 43 orang dengan menggunakan teknik pengambilan sampling dengan 43 orang. Metode pengumpulan data meliputi data primer, data sekunder, dan data tersier. Analisis data yang digunakan adalah analisis univariat dan bivariat dengan menggunakan uji statistik chi-square. Hasil penelitian menunjukkan bahwa kepribadian pegawai p(0,001), faktor eksternal p(0,001), struktur kompensasi p(0,004), dan politik dalam organisasi p(0,024) berhubungan dengan pengembangan profesi bidan. Hubungan pegawai dan organisasi tidak bergantung pada pengembangan profesi kebidanan p(0,431). Hasil penelitian menyimpulkan bahwa kepribadian pegawai, faktor eksternal, serta sistem dan kebijakan kompensasi internal berhubungan dengan pengembangan profesi kebidanan, sedangkan hubungan pegawai dengan organisasi berhubungan dengan pengembangan profesional kebidanan, artinya tidak. Diharapkan Puskesmas dapat mengembangkan kebijakan yang fokus pada bidan di segala aspek, antara lain pelatihan pengelolaan organisasi yang baik dan tanggung jawab profesional, peningkatan kesejahteraan pegawai dan penciptaan lingkungan kerja yang nyaman.
The Relationship between Body Mass Index and Hemoglobin Levels in Young Girls at SMA Muhammadiyah 7 Yogyakarta
Authors: Nafisa Amalia Nafisa , Budi Rahayu  
Published: November 2023

Background: Anemia is a health problem in Indonesia. Based on the 2018 Riskesdas data, the prevalence of anemia in adolescents is 32%, with mostly young women experiencing it. Anemia is often associated with nutritional problems, namely a lack of nutrients, especially iron, which can cause anemia. Adolescents need nutrition to assist in growth and development. To monitor a person's nutritional status can be done using the body mass index (BMI).
Purpose: To determine the relationship between body mass index (BMI) and hemoglobin levels in class XI SMA Muhammadiyah 7 Yogyakarta.
Methods: This study used an analytic observational research method with a cross-sectional design. Samples were taken using the total sampling technique, namely 28 female students. Data collection was carried out by measuring body mass index and examining hemoglobin levels, as well as data analysis using bivariate analysis of the Spearman-Rho correlation test.
Results: The results showed that 2 people (7.1%) with a very low BMI had mild anemia, 1 person (3.6%) with a very thin BMI had moderate anemia, 2 people (7.1%) with a low BMI had moderate anemia, and 5 people (17.9%) with a normal BMI had mild anemia. The results of the Spearman Rho test data analysis showed that there was a relationship between body mass index and hemoglobin levels, with a significance value of p = 0.002 (p <0.05).
Conclusion: There is a relationship between body mass index and hemoglobin levels in young women in the SMA Muhammadiyah 7 Yogyakarta.
Environmentally friendly synthesis of lead halide perovskites using aqueous solutions
Authors: Era Masanao , Kariya Youhei 
Published: November 2023

Abstract
In this study, we demonstrate a successful method to synthesize lead halide perovskites (CH3NH3PbX3, X = Br, and I) by immersing lead halides (PbX2) powder in saturated aqueous solutions of methyl ammonium halides (CH3NH3X). Our analysis of reflection spectra and X-ray diffraction profiles confirmed the formation of the lead halide perovskite structures with this exposure process. This approach provides a promising pathway for environmentally friendly perovskite solar cells, eliminating the need for toxic polar organic solvents (for example, DMF, DMSO and so on) commonly employed in conventional perovskite solar cell fabrication.
Circulating Tumor DNA as an Early Biomarker of Efficacy of Targeted and Chemotherapy
Authors: Кулигина Екатерина Шотовна , Янус Григорий Аркадьевич , Мартьянов Александр Сергеевич , Горгуль Юлий Андреевич , Степанова Екатерина Олеговна , Моисеенко Федор Владимирович , Имянитов Евгений Наумович 
Published: November 2023

Концентрация циркулирующих опухолевых ДНК (цоДНК) в крови является чувствительным и специфичным маркером для мониторинга в режиме реального времени динамики опухолевой массы. Количественный анализ цоДНК дает возможность оценить ответ опухоли на терапию на самых ранних этапах воздействия, а неинвазивный характер подобной процедуры («жидкостной биопсии») делает ее незаменимой в случаях малой доступности и множественности опухолевых очагов. Важно, что изменение спектра «циркулирующих» мутаций достаточно полно отражает эволюцию неопластических клонов и механизмы молекулярной адаптации клеток к воздействию препаратов — эта информация крайне ценна для своевременной коррекции терапевтической схемы на стадиях, предшествующих клинической манифестации прогрессирования. Многочисленные клинические испытания динамики цоДНК у пациентов, получающих таргетные или химиотерапевтические препараты, продемонстрировали как прогностическую, так и предиктивную ценность данного подхода. Эти усилия подчеркивают растущую роль жидкостной биопсии при выборе тактики на всех этапах лечения с момента постановки диагноза: в отборе пациентов для таргетной или иммунотерапии терапии на основании молекулярных свойств опухоли, мониторинге эффективности препаратов, определении оптимальной продолжительности терапии, диагностике рецидивов. Данный обзор суммирует накопленные к настоящему моменту сведения об успехах и ограничениях использования цоДНК в роли клинически значимого экспресс-маркера для оценки эффективности противоопухолевой терапии на примере основных онкологических локализаций: рака толстой кишки, рака легкого, рака молочной железы, яичника, простаты и т. д.
Saccade execution increases the preview effect with faces: An EEG and eye-tracking coregistration study
Authors: Huber-Huber Christoph , Melcher David 
Published: November 2023

Abstract
Under naturalistic viewing conditions, humans conduct about three to four saccadic eye movements per second. These dynamics imply that in real life, humans rarely see something completely new; there is usually a preview of the upcoming foveal input from extrafoveal regions of the visual field. In line with results from the field of reading research, we have shown with EEG and eye-tracking coregistration that an extrafoveal preview also affects postsaccadic visual object processing and facilitates discrimination. Here, we ask whether this preview effect in the fixation-locked N170, and in manual responses to the postsaccadic target face (tilt discrimination), requires saccade execution. Participants performed a gaze-contingent experiment in which extrafoveal face images could change their orientation during a saccade directed to them. In a control block, participants maintained stable gaze throughout the experiment and the extrafoveal face reappeared foveally after a simulated saccade latency. Compared with this no-saccade condition, the neural and the behavioral preview effects were much larger in the saccade condition. We also found shorter first fixation durations after an invalid preview, which is in contrast to reading studies. We interpret the increased preview effect under saccade execution as the result of the additional sensorimotor processes that come with gaze behavior compared with visual perception under stable fixation. In addition, our findings call into question whether EEG studies with fixed gaze capture key properties and dynamics of active, natural vision.
Pelatihan Penggunaan Media Augmented Reality dan Teknik Edukasi pada Bidan dalam Upaya Peningkatan Kualitas Edukasi pada layanan Kebidanan
Authors: Sudirman Jumrah , Stang  , Ikhsan Amar Muh , B Suriani 
Published: November 2023

Teknologi merupakan hal yang tidak dapat dipisahkan dari kehidupan manusia. Adanya teknologi dapat membantu aktivitas manusia tersebut menjadi lebih mudah. Kegiatan pengabdian ini dilakukan untuk melakukan pelatihan kepada bidan sebagai Upaya meningkatkan kemampuan bidan dalam mendesain media edukasi dengan teknologi Augmented Reality. Pelaksanaan Kegiatan dilakukan di Sekretariat Pengurus Daerah IBI Provinsi Sulawesi Selatan, dimana peserta mengikuti kegiatan sebanyak 40 peserta. Metode yang digunakan adalah ceramah, diskusi dan simulasi. Pelaksaan kegiatan ini bermitra dengan Pengurus Daerah IBI Provinsi Sulawesi Selatan. Hasil yang didapatkan menunjukkan peserta yang mengisi postes terdapat 34 peserta (85%) dengan pengetahuan yang baik dan 6 peserta (15%) dengan pengetahuan yang cukup. Kegiatan terlaksana dengan tertib sesuai rencana kegiatan.

Technology is something that cannot be separated from human life. The existence of technology can help human activities become easier. This service activity is carried out to conduct training for midwives as an effort to improve the ability of midwives in designing educational media with Augmented Reality technology. Implementation of the activity was carried out at the IBI Regional Management Secretariat of South Sulawesi Province, where participants took part in the activity as many as 40 participants. The methods used are lectures, discussions and simulations. The implementation of this activity partnered with the IBI Regional Management of South Sulawesi Province. The results obtained showed that the participants who filled out the posttest were 34 participants (85%) with good knowledge and 6 participants (15%) with sufficient knowledge. Activities carried out in an orderly manner according to the activity plan.