bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of radical‐based damage of RNase A in aqueous solution and lipid vesicles
Authors: Torreggiani Armida , Tamba Maurizio , Manco Immacolata , Faraone‐Mennella M. R. , Ferreri Carla , Chatgilialoglu C. 
Published: September 2005

AbstractThe γ‐irradiation of bovine pancreatic ribonuclease A (RNase A) in aqueous solution were investigated at different doses by vibrational spectroscopy as well as enzymatic assay, electrophoresis, and HPLC analysis. Both functional and structural changes of the protein were caused by attack of H• atoms and •OH radicals. In particular, Raman spectroscopy was shown to be a useful tool in identifying conformational changes of the protein structure and amino acidic residues that are preferential sites of the radical attack (i.e., tyrosine and methionine). After partial structural changes by the initial radical attack, the internal sulfur‐containing amino acid residues were rendered susceptible to transformation. By using the biomimetic model of dioleoyl phosphatidyl choline vesicle suspensions containing RNase A, the damage to methione residues could be connected to a parallel alteration of membrane unsaturated lipids. In fact, thiyl radical species formed from protein degradation can diffuse into the lipid bilayer and cause isomerization of the naturally occurring cis double bonds. As a consequence, trans unsaturated fatty acids are formed in vesicles and can be considered to be markers of this protein damage. © 2005 Wiley Periodicals, Inc. Biopolymers 81: 39–50, 2006This article was originally published online as an accepted preprint. The “Published Online” date corresponds to the preprint version. You can request a copy of the preprint by emailing the Biopolymers editorial office at biopolymers@wiley.com
Blob‐based liquid morphing
Authors: Jin Xiaogang , Liu Shengjun , C. L. Wang Charlie , Feng Jieqing , Sun Hanqiu 
Published: September 2005

AbstractIn this paper, we propose a novel practical method for blob‐based liquid 3D morphing. Firstly, blobby objects are employed to approximate a given polygonal surface. The primitives in the medial axis sphere‐tree of a polygonal model are utilized as initial blobs—this greatly improves the robustness and efficiency of the blob‐based approximation. Secondly, we establish the blob correspondences between two models by sphere cellular matching and hierarchical matching. Finally, we interpolate the parameters of the implicit representation to get the intermediate shapes. Experiments show our method can produce visually pleasing liquid morphing effects. Copyright © 2005 John Wiley & Sons, Ltd.
Dynamic modeling and rendering of grass wagging in wind
Authors: Wang Changbo , Wang Zhangye , Zhou Qi , Song Chengfang , Guan Yu , Peng Qunsheng 
Published: September 2005

AbstractSimulation of dynamic natural scene is one of the most challenging tasks in computer graphics. In this paper, we propose a new approach to dynamic modeling and rendering of grasses wagging in wind. Through length preserving free‐form deformation of the 3D skeleton lines of each grass blade and using the alpha test to implement transparent texture mapping, we successfully model grasses of different shapes with rich details. To simulate the real time waggle of grasses, the grasses of a meadow are represented in LOD, while their skeleton lines are dynamically deformed according to some physical models. Simplification technique is also employed to accelerate the collision detection between neighboring grasses. Experiments show that our method can realistically render the animated grass scenes under wind of different speeds and types in real time. Copyright © 2005 John Wiley & Sons, Ltd.
Is paraoxonase 192 gene polymorphism a risk factor for membranoproliferative glomerulonephritis in children?
Authors: Bilge Ilmay , Sirin Aydan , Agachan Bedia , Emre Sevinc , Sadıkoglu Banu , Yılmaz Hülya , Sucu Aysegül , İsbir Turgay 
Published: September 2005

AbstractWe investigated the effects of paraoxonase (PON1) 192 polymorphism on serum PON1 activity and the impact of phenotypic expression on the risk and prognosis of Turkish children with membranoproliferative glomerulonephritis (MPGN). Eighteen children with biopsy‐proven Type I MPGN (10 boys, 8 girls) and age‐matched 53 healthy controls were included in the study. PCR (polymerase chain reaction), RFLP (restriction fragment length polymorphism) and agarose gel electrophoresis techniques were used to determine the PON1 192 genotype. PON1 activity was measured by spectrophotometric assay of p‐nitrophenol production following addition of paraoxon. We found that PON1 192 genotype distribution (AA, AB, BB) in MPGN patients were 61.1%, 22.3%, 16.6% and 15.1%, 35.8%, 49.1% in controls, respectively. The frequency of AA genotypes was significantly higher in the MPGN group (0.611) compared with the healthy controls (0.151) (p < 0.001). Although the serum PON1 activity was lower in MPGN patients (103.3 ± 55.2 U/l) than the healthy controls (130.9 ± 71.2 U/mol), the difference was not statistically significant (p = 0.0563). In the genotypes of patients and controls classified according to PON1 A/B polymorphism; serum PON1 activities were significantly increased (p < 0.001, ANOVA) in the order of PON1 AA, AB and BB in both MPGN patients (82.4, 91.7 and 173.6 U/l) and healthy controls (85.9, 119.9 and 193.1 U/l), respectively. There was a significant relationship between the poor prognosis and having AA genotype and low PON1 activity. Of the 8 patients with poor prognosis, 7 had genotype AA and the remaining one was AB heterozygote. Our results suggest that homozygosity for the A allele might have an important role on the risk for developing MPGN and may also be associated with the poor prognosis of disease. In conclusion, we suggest that the PON1 activities are affected by PON1 genetic variability in Turkish patients with MPGN. Copyright © 2005 John Wiley & Sons, Ltd.
Overexpression of caspase recruitment domain (CARD) membrane‐associated guanylate kinase 1 (CARMA1) and CARD9 in primary gastric B‐cell lymphoma
Authors: Nakamura Shigeo , Nakamura Shotaro , Matsumoto Takayuki , Yada Shinichiro , Hirahashi Minako , Suekane Hiroshi , Yao Takashi , Goda Kenichi , Iida Mitsuo 
Published: September 2005

AbstractBACKGROUNDAlthough caspase recruitment domain (CARD) membrane‐associated guanylate kinase (MAGUK) protein 1 (CARMA1) and CARD9 play important roles in lymphocyte activation, the significance of CARMA1 and CARD9 in the pathogenesis of gastric mucosa‐associated lymphoid tissue (MALT) lymphoma remains to be elucidated.METHODSBy using reverse transcription‐polymerase chain reaction analysis, the expression levels of mRNA of CARMA1, CARD9, Bcl10, and the apoptosis inhibitor 2 (API2)‐MALT1 chimeric transcript were determined in tissue specimens from 65 patients with primary gastric B‐cell lymphoma (43 patients with low‐grade MALT lymphoma, 16 patients with MALT lymphoma plus diffuse large B‐cell lymphoma [DLBL], and 6 patients with DLBL without MALT lymphoma) and in tissue specimens from 18 patients with chronic gastritis. The expression levels of CARMA1 and BCL10 were examined immunohistochemically in 30 patients with lymphoma.RESULTSCARMA1 mRNA was detected in 55% of lymphoma patients but in only 17% of chronic gastritis patients. The positive rates for CARD9, Bcl10, and API2‐MALT1 chimeric transcript in the lymphoma patients were 48%, 98%, and 8%, respectively, whereas the 3 molecules were not detected in any specimens from patients with chronic gastritis. The expression of CARMA1 and CARD9 was frequent in the Helicobacter pylori‐negative patients (100% and 86%, respectively), in the API2‐MALT1 chimeric transcript‐positive patients (100% and 100%, respectively), and in the specimens from patients who did not respond to H. pylori eradication (76% and 71%, respectively). In addition, CARMA1 expression was positive more frequently in patients of DLBL without MALT lymphoma (100%) than in patients of MALT lymphoma (51%). CARMA1 protein expression was correlated significantly with the expression of CARMA1 mRNA and also with the expression of nuclear BCL10.CONCLUSIONSThe overexpression of CARMA1 and CARD9 presumably is associated with the development or progression of gastric B‐cell lymphoma, especially among patients who have disease in which the pathogenesis is not related to H. pylori. Cancer 2005. © 2005 American Cancer Society.
A long‐term follow‐up and management study of hepatocellular carcinoma patients surviving for 10 years or longer after curative hepatectomy
Authors: Shimada Kazuaki , Sano Tsuyoshi , Sakamoto Yoshihiro , Kosuge Tomoo 
Published: September 2005

AbstractBACKGROUNDThe aims of the current study were to elucidate the clinicopathologic characteristics and disease recurrence patterns of patients with hepatocellular carcinoma (HCC) who survived for 10 years or longer after undergoing an initial hepatectomy.METHODSBetween January 1987 and December 1993, 578 patients underwent potentially curative hepatectomy at the study institution. Disease recurrence and follow‐up data were available for 481 of these patients, who then were followed for more than 10 years after the initial hepatectomy. Fourteen clinicopathologic features were compared between the 10‐year survivors and those patients who died within 10 years after the surgery. The risk factors for disease recurrence, the recurrence status, time to recurrence, and treatment modalities for recurrence were examined among the 10‐year survivors.RESULTSThere were 105 10‐year survivors (21.8%), including 42 disease‐free survivors (8.7%). Favorable independent factors found to be correlated with 10‐year survival were age < 55 years, a plasma retention rate of indocyanine green at 15 minutes of < 15%, the presence of a solitary tumor, the absence of intrahepatic metastases, the absence of portal vein invasion, and the absence of underlying cirrhosis. A negative test for the the hepatitis C antibody and the absence of intrahepatic metastases were found to be independent predictive factors for 10‐year disease‐free survival among the 10‐year survivors.CONCLUSIONSThe results suggest that younger patients without underlying cirrhosis who have a solitary HCC that does not demonstrate vascular invasion might survive for longer than 10 years after the initial hepatectomy. In addition to close surveillance in such patients after hepatectomy, repeat hepatectomy, local ablation therapy, and transhepatic arterial chemoembolization may contribute to long‐term survival, even if disease recurrence occurs. Cancer 2005. © 2005 American Cancer Society.
Additivity properties of graphs with Form II symmetry
Authors: Kaveh A. , Sayarinejad M. A. 
Published: September 2005

AbstractIn this paper, the properties of previously developed Form II symmetry (Commun. Numer. Meth. Engng 2003; 19:125–136; 2004; 20:133–146) is further investigated. Additivity properties of graphs with this form are formulated, and the effect of adding or deleting members on the eigenvalues of the Laplacian matrices of the corresponding graphs, is studied. Depending on the category of the added or deleted members, the condensed submatrices on which changes occur are identified, and the necessary modifications are suggested. A mass‐spring dynamic system is presented to illustrate a typical application of the latter approach. Copyright © 2005 John Wiley & Sons, Ltd.
Iterative solution technique in selective mass scaling
Authors: Olovsson Lars , Simonsson Kjell 
Published: September 2005

AbstractSelective mass scaling in explicit finite element analyses is a method to increase the critical time step by modifying the mass matrix while at the same time leaving the rigid body translational behaviour unaffected. In an earlier work it has been suggested to calculate the global acceleration vector as a=M̄−1f where M̄ is the selectively scaled global mass matrix and where f is the global node force vector. However, dealing with large models, the mass matrix inversion is computationally costly and the storage of M̄−1 requires a considerable amount of memory space. In this context it is here shown that an iterative solution technique, where M̄a=f is solved every time step, can be an attractive alternative to inverting the mass matrix. Copyright © 2005 John Wiley & Sons, Ltd.
Harmonic balance method for FEM analysis of fluid flow in a vibrating pipe
Authors: Ragulskis M. , Fedaravicius A. , Ragulskis K. 
Published: September 2005

AbstractA numerical procedure for the analysis of non‐Newtonian fluid flow in a longitudinally vibrating tube is developed. The formulation of the problem is presented in differential equation form and finite element model is developed leading to the first‐order matrix differential equation. A special modification of the harmonic balance procedure is proposed for this non‐linear problem. Numerical validation of the harmonic balance procedure was performed by comparison of the average mass flow rate with the results of direct time integration. Copyright © 2005 John Wiley & Sons, Ltd.
Numerical method for determination of reworking or scraping the defective items in a finite production rate model
Authors: Chiu Yuan‐Shyi P. , Chiu Singa Wang , Chao Huang‐Chieh 
Published: September 2005

AbstractThis paper presents a numerical method for determination of reworking or scraping defective items in a finite production rate model with backlogging permitted. In most practical manufacturing settings, due to process deterioration or other factors, generation of defective items is inevitable. The defective items can either be repaired or be discarded. In the finite production model we studied, the defective rate is assumed to be a random variable and the rework process can start immediately when regular production ends. The optimal lot sizes and the expected annual inventory costs for the cases of production systems with the rework process and without the rework process are compared and analysed. A set of numerical equations are developed to assist in determining on whether or not it is beneficial to rework defective items. A numerical example is provided to demonstrate their practical usages. Copyright © 2005 John Wiley & Sons, Ltd.
P2broadcast: a hierarchical clustering live video streaming system for P2P networks
Authors: Liu De‐Kai , Hwang Ren‐Hung 
Published: September 2005

AbstractThis work describes a novel live video streaming system for P2P networks, referred to as P2broadcast. The video streaming service has bandwidth requirements to guarantee presentation quality. Therefore, a scalable strategy to quickly find a path from a media server to a client with abundant bandwidth is very important. A common approach in the literature is the bandwidth first (BF) scheme, which allows a newcomer to adopt a BF tree traversal scheme to find its parent peer on the P2P overlay tree to retrieve the media content. The BF scheme is likely to build a deep overlay tree, resulting in long start‐up latency as the number of peers on the overlay tree grows. P2broadcast reduces start‐up latency by organizing peers into hierarchical clusters and making the overlay tree become a ‘short‐and‐wide’ tree. The hierarchical clustering structure enables a newcomer to find its parent peer among the set of peers that are more likely to provide large available bandwidth only. Limiting the set of potential parent peers not only reduces start‐up latency but also improves the system availability. Additionally, unlike the BF scheme that only concerns available bandwidth, P2broadcast utilizes a cost function to evaluate the appropriateness of a potential parent peer. The cost function considers the depth of the newcomer on the overlay tree, making the overlay tree become a short‐and‐wide tree. In addition to start‐up latency reduction, the short‐and‐wide tree feature also alleviates the service interruption probability due to the leaving or failure of a peer. Our simulation results show that P2broadcast greatly outperforms the BF scheme in terms of system availability, and achieves around 66% savings in start‐up latency and 10% decrement in service interruption probability. Copyright © 2005 John Wiley & Sons, Ltd.
Resource discovery and management in computational GRID environments
Authors: Bradley Alan , Curran Kevin , Parr Gerard 
Published: September 2005

AbstractCorporations are currently using computational GRIDs to improve their operations. Future GRIDs will allow an organization to take advantage of computational GRIDs without having to develop a custom in‐house solution. GRID resource providers (GRPs) make resources available on the GRID so that others may subscribe and use these resources. GRPs will allow companies to make use of a range of resources such as processing power or mass storage. However, simply providing resources is not enough to ensure the success of a computational GRID: Access to these resources must be controlled otherwise computational GRIDs will simply evolve to become a victim of their own success, unable to offer a suitable quality of service (QoS) to any user. The task of providing a standard querying mechanism for computational GRID environments (CGE) has already witnessed considerable work from groups such as the Globus project who have delivered the Metacomputing Directory Service (MDS), which provides a means to query devices attached to the GRID. This paper presents a review of existing resource discovery mechanisms within CGE. Copyright © 2005 John Wiley & Sons, Ltd.
Tool assisted H.323 dial‐plan design following formally defined strategies
Authors: Knezevic Milos , Stassinopoulos George 
Published: September 2005

AbstractThis paper considers H.323 v4 VoIP networks consisting of gateways and gatekeepers, addressing the task of terminating calls to multiple ISDN networks. Our goal is the maximal utilization of the gatekeeper's centralized routing mechanism for call termination to ISDN networks based on load balancing and resource availability indication (RAI), thus minimizing the need for usage of unwanted (second attempt) overflow mechanisms. We elaborate on the drawbacks of overflow mechanisms and give an overview on different solutions offered in practice by vendors. The discussion justifies the emphasis on load balancing, thus we present an algorithm and tool assisted approach for the systematic assignment of PRIs from ISDN networks to gateways. We follow strictly defined design criteria that lead to an optimized network dial‐plan. We thus offer a stand alone, off‐line solution without the need of any extra add‐ons or upgrades. This is intended to replace the purely intuitive approach followed by today's planners.Our scope is the design rather than the runtime environment; the latter continues to feature the simplicity of a single global RAI per gateway. We consider desirable and non‐desirable link distribution topologies between gateways and ISDN networks based on operational and economic evaluation criteria. These measure the number of ‘wasted’ gateway ports or ‘inappropriately’ allocated network interfaces. Our approach is illustrated through a worked out example showing key features of the proposed algorithm and revealing characteristic cases met in the ISDN interface allocation.Finally, we show how the presented methodology, which presently addresses a H.323 design issue, can provide performance benefits in the VoIP technologies of the immediate future. Copyright © 2005 John Wiley & Sons, Ltd.
Ruthenium Complexes Containing Chiral N‐Donor Ligands as Catalysts in Acetophenone Hydrogen Transfer – New Amino Effect on Enantioselectivity
Authors: Gómez Montserrat , Jansat Susanna , Muller Guillermo , Aullón Gabriel , Maestro Miguel Angel 
Published: September 2005

AbstractNew p‐cymene ruthenium species containing chiral amino alcohols (1–3), primary (4–7) and secondary (8, 9) amino‐oxazolines, were tested as catalysts in the hydrogen transfer of acetophenone, using 2‐propanol as the hydrogen source. A remarkable effect on the enantioselectivity, but also on the activity, was observed depending on the amino‐type oxazoline, Ru/8 and Ru/9 being low active and nonselective catalytic systems, in contrast to their primary counterpart Ru/5. Complexes containing amino‐oxazolines (10–12) were prepared and fully characterized, both in solution and in solid state. The X‐ray structure was determined for (SRu,RC)‐10. The diastereomeric ratios observed for complexes 10 and 11 were determined by 1H NMR and confirmed by means of structural modeling (semi‐empirical PM3(tm) level). DFT theoretical calculations for the transition states involved in the hydrogen transfer process proved the important differences in their relative populations, which could justify the enantioselectivity divergences observed between primary and secondary amino‐oxazoline ruthenium systems. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
Rainfall‐induced landslide hazard assessment using artificial neural networks
Authors: Wang H. B. , Sassa K. 
Published: September 2005

AbstractIn Japan, landslides triggered by heavy rainfall tend to occur during the annual rainy season from early June until the middle of July; these landslides constitute a major hazard causing significant property damage and loss of life. This paper proposes the use of back propagation neural networks (BPNN) to predict the probability of landslide occurrence for a scenario of heavy rainfall in the Minamata area of southern Kyushu Island, Japan. All of the landslides were detected from aerial photographs taken in 1999, 2001 and 2003, and a geospatial database of lithology, topography, soil characteristics, land use and precipitation was constructed using geographical information systems (GIS). The training sample consists of 602 cells that include landslide activity and 1600 cells in stable areas. Using the trained BPNN with 49 input nodes, three hidden layers, and one output node, 239 589 cells were processed to produce a map of landslide probability for a maximum daily precipitation of 329 mm and a maximum cumulative precipitation of 581 mm for an incessant, intense rainfall event in the future. The resultant hazard map was classified into four hazard levels; it can be referenced for land‐use planning and decision‐making for community development. Copyright © 2005 John Wiley & Sons, Ltd.
On digital signatures in ad hoc networks
Authors: Westhoff D. , Lamparter B. , Paar C. , Weimerskirch A. 
Published: September 2005

AbstractCryptographic primitives need to be carefully evaluated when being applied in components ensuring enhanced protection aims. This work analyses the performance of RSA‐ and ECDSA‐based digital signature schemes in the context of multi‐hop ad hoc networks. Our work shows that contrary to a single wireless hop scenario with restricted clients in the wireless network and a powerful server in the fixed network, the choice of an appropriate signature candidate is not as obvious as for the aforementioned architecture. Our performance analysis considers three partially interdependent axes (a) the required security level, (b) the device restriction and (c) the protocol specification with the required security relationships, and the assumed traffic flow. We take (c) into account by analysing two charging protocols for wireless multi‐hop scenarios. By generalising our observations, we carefully derive some recommendations to strengthen the security engineering process for dependable distributed systems over the wireless network. Copyright © 2005 AEIT.