bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prognostic analysis of prostaglandin D2 synthase in diffuse large B-cell lymphoma
Authors: Wang Jiesong , Xu Yun , Yu Wei , Zheng Yanbin , He Hongming , Chen Daoguang , Zou Siping , Wang Chang , Chen Ying , Chen Ningbin , Wu Hui , Wang Jianchao , Lin Jianyang 
Published: October 2023

Abstract
Purpose
We aimed to analyse the correlation between prostaglandin D2 synthase (PTGDS) and a diffuse large B-cell lymphoma (DLBCL) prognosis.

Methods
We retrospectively collected two hundred paraffin-embedded tissue specimens that were pathologically diagnosed as DLBCL in the Fujian Tumour Hospital between January 2014 and December 2018. An abundance of paraffin-embedded tumour tissues were obtained. Twenty patients with lymphocyte-rich, benign, tissue-reactive, hypertrophic tonsillitis were selected as controls. Wax blocks were selected for primary cases and the controls were screened by professional pathologists. The levels of prostaglandin D2 synthase (PTGDS) and the EMT-related molecules, E-cadherin and vimentin, were detected by immunohistochemistry in clinical samples. A chi-square test revealed the correlations between PTGDS expression and clinicopathological characteristics, including age, sex, primary site, clinical stage, immunotyping, and International Prognostic Index (IPI) score. The Kaplan–Meier survival analysis was performed, and the diagnostic value was evaluated by receiver operating characteristic (ROC) curve analysis.

Results
A total of 138 cases (69%) were found to be PTGDS positive (> 30% positive cells). PTGDS staining was negative (< 30% positive cells) in 62 cases (31%). We collected the corresponding clinicopathological information and found that PTGDS expression was not significantly related to the patients’ age, tumour stage, presence of extranodal invasion, or IPI score. According to the follow-up data, patients with low PTGDS expression had poor progression-free survival (PFS) and overall survival (OS), with 2-year PFS and OS rates of 41.7% and 50%, respectively. The 2-year PFS and OS rates of PTGDS-positive patients were 89.3% and 92.9%, respectively (P < 0.0001), and the differences were significant.

Conclusion
We found that the expression level of PTGDS is significantly correlated with the prognosis of diffuse large B-cell lymphoma.
Founding Narratives and Men's Political Ambition: Experimental Evidence from US Civics Lessons
Authors: Clayton Amanda , O'Brien Diana Z. , Piscopo Jennifer M. 
Published: October 2023

AbstractOne oft-cited reason for women's political underrepresentation is that women express less political ambition than men. We reframe the puzzle of women's ambition deficit, asking why men have an ambition surplus. Drawing on the concept of symbolic representation, we theorize that political symbols convey to men their capacity for exceptional political leadership. We test our expectations with a US-based survey experiment in which respondents watch one of three ‘two-minute civics lessons’. Men who watched a video featuring the accomplishments of the Founding Fathers reported significantly more political ambition than men assigned to the control group. Additional studies indicate that the effects are specific to the Founding Fathers (as compared to early American statesmen). Men are also more likely than women to identify the Founding Fathers as inspiring figures and to feel pride when considering them. Our findings suggest how history is told contributes to men's persistent political overrepresentation.
Reconstructing the Labour of Care in Early Modern England
Authors: Mansell Charmian 
Published: October 2023

AbstractUncertainty about what constitutes work in the past has led to the labour of care occupying a shadowy place in the histories of both medicine and the economy. This article takes a microhistorical approach to shed new light on care in early modern England. Using depositions and other surviving records of a testamentary dispute heard in the Hereford diocesan church court in 1674–5, the article reconstructs the care received by a single, labouring man named Richard Howell. Focusing on forms of care that lay outside institutions, it unpicks the varieties of informal labour that society understood as care work in early modern England, including maintenance (provision of economic support for the sick, including lodging, food, and drink); physical or practical care (watching or attending the sick); and the emotional labour of care. The article challenges the idea that care work was simply undertaken by the family or carried out within a system of social obligation. It demonstrates that all forms of care in this pre-industrial society implicitly (and sometimes explicitly) held economic value, which could be leveraged as grounds for economic recompense in the early modern courts.
Judicial Reform or Abusive Constitutionalism in Israel
Authors: Roznai Yaniv , Dixon Rosalind , Landau David E 
Published: October 2023

AbstractHow should the constitutional reform in Israel be assessed in comparative terms? Comparative constitutional understandings point to the centrality of three key sets of norms as part of the ‘democratic minimum core’: (i) commitments to free and fair, regular multi-party elections; (ii) political rights and freedoms; and (iii) a system of institutional checks and balances necessary to maintain (i) and (ii). Any change in judicial power and independence must be assessed against the benchmark of the democratic minimum core, and by reference to its cumulative practical effect on a system of institutional checks and balances.We claim that recent changes in Israel may already threaten these institutional checks, and have the potential to do more damage in the future, if given broad effect and if combined with further changes in the power and independence of the Supreme Court. On this basis, we suggest, the relevant changes should be viewed as either ‘abusive’ or ‘proto-abusive’ in nature. By threatening to undermine both the power and independence of the Supreme Court of Israel, they directly threaten the health of the constitutional checks and balances system and, hence, the ‘democratic minimum core’ in Israel.
Hepatitis B antibody levels after different doses of hepatitis B vaccination: a retrospective study based on hospitalized children
Authors: Chai Yu , Tang Jihai , Su Yin , Xuan Kun , Xu Lili , Hao Jiayan , Lu Zhijian , Wang BinBing , Chen Xia , Luo Xianwei , He Jiali , Zhu Lijuan 
Published: October 2023

Abstract
Many studies have investigated the positivity rate of hepatitis B surface antibody (HBsAb) after hepatitis B vaccine (HepB) immunization. However, the antibody level, assessed monthly or at more frequent intervals after each of the three doses, particularly within the first year after birth, has not been previously reported. To elucidate the level of antibody formation at various times after vaccination, the current study used the available detection data of HBsAb in hospitalized children to analyze the HBsAb level after immunization combined with their vaccination history. Both the positivity rate and geometric mean concentration (GMC) increased sequentially with immunization doses, reaching their peaks earlier after the third dose than after the first two doses, and the rate of HBsAb positivity was able to reach 100% between 11 and 90 days after completing the three doses of HepB. Within one year after receiving the three doses, the antibody positivity rate and GMC were maintained above 90% and 100 mIU/mL, respectively, and subsequently steadily declined, reaching the lowest value in the 9th and 10th years. The current findings reveal, in more detail, the level of antibody formation at different times following each dose of HepB in hospitalized children, particularly in the age group up to one year after vaccination. For the subjects of this study, we prefer to believe that the proportion of HBsAb non-response should be less than 5% after full immunization with HepB, provided that the appropriate time for blood collection is chosen.
Pathways to depalatalization of the palatal nasal in Quebec and hexagonal French: An EPG study
Authors: Colantoni Laura , Kochetov Alexei , Steele Jeffrey 
Published: October 2023

AbstractThe palatal nasal is one of French’s most variable consonants with attested variants including [ɲ] alongside [nj] and, less frequently, [n] and [ŋ]. Variation is conditioned by both linguistic (position in the word, lexical item, flanking vowels) and speaker variables (in particular, variety). Except for insights provided by the studies reviewed in Recasens (2013), little is known of the articulatory properties of French /ɲ/ including the degree of inter-varietal and -speaker variation or the proportion of coronal and velar depalatalized realizations. We present here an electropalatographic (EPG) study of two European (EF) and two Quebec French (QF) speakers’ /ɲ/ production in both word-medial and -final positions in isolated and contextualized words. Quantitative indices and qualitative investigation of the linguopalatal contact profiles reveal that the EF speakers produced a relatively anterior /ɲ/, differing minimally from /n/ followed by /j/. Whereas one of their QF peers produced uniquely backed velar realizations of /ɲ/, the other speaker had fronted alveolopalatal variants word-medially versus backed velar realizations word-finally, with the latter differing minimally from the /ŋ/ of jogging. These findings are consistent with pathways to depalatalization observed in other Romance varieties and call into question the phonemic status of the palatal nasal in French.
Parental support for free school lunches in Australian primary schools: associated factors and perceived barriers
Authors: Aydin Gozde , Margerison Claire , Worsley Anthony , Booth Alison 
Published: October 2023

AbstractObjective:(1) To explore the feasibility of such programmes in Australia, this study examined parents’ views on free school lunch provision. (2) To examine the associations between parents’ demographic and personal characteristics and their support for free universal school lunches.Design:An online cross-sectional survey of parents.Setting:Australia, April 2021.Participants:Seven hundred and eighty-seven parents took the survey. They had a mean age of 40. The respondents were predominantly female (95 %) and had a university degree (72 %).Results:Fifty-three percentage of the respondents agreed that all students should have access to healthy and well-balanced, free school lunches. Parents were concerned about healthiness, catering, allergies and cost of school-provided school lunches. Ethnic background, universalism values and education levels were significantly associated with support for free school lunch provision. Non-native English-speaking parents were almost three times more likely to support free universal lunches in primary schools than their native English-speaking counterparts. Parents with higher universalism-concern values were more likely to endorse free lunches in primary school. However, the level of education was negatively associated with parents’ support for free school lunches.Conclusions:The survey results highlight the complexity of parental views on free school lunch provision. Parents’ concerns regarding lunches should be considered in developing school lunch programmes that meet the needs and preferences of diverse communities. These findings can be used to guide future primary school lunch provision initiatives.
Nutritional, environmental and economic impacts of ultra-processed food consumption in Australia
Authors: Liyanapathirana Navoda Nirmani , Grech Amanda , Li Mengyu , Malik Arunima , Ribeiro Rosilene , Burykin Timur , Lenzen Manfred , Raubenheimer David 
Published: October 2023

AbstractObjective:To quantify the full life cycle impacts of ultra-processed foods (UPF) for key environmental, economic and nutritional indicators to identify trade-offs between UPF contribution to broad-scope sustainability.Design:Using 24-h dietary recalls along with an input–output database for the Australian economy, dietary environmental and economic impacts were quantified in this national representative cross-sectional analysis. Food items were classified into non-UPF and UPF using the NOVA system, and dietary energy contribution from non-UPF and UPF fractions in diets was estimated. Thereafter, associations between nutritional, environmental and economic impacts of non-UPF and UPF fractions of diets were examined using a multi-dimensional nutritional geometry representation.Setting:National Nutrition and Physical Activity Survey 2011–2012 of Australia.Participants:Respondents (n 5344) aged > 18 years with 1 d of 24-h dietary recall data excluding respondents with missing values and outlier data points and under reporters.Results:Australian diets rich in UPF were associated with reduced nutritional quality, high greenhouse gas emissions, energy use, and increased employment and income associated with the food supply chains. The environmental and economic impacts associated with the UPF portion of diets become more distinct when the diets are standardised to average protein recommendation.Conclusion:Increased consumption of UPF has socio-economic benefits, but this comes with adverse effects on the environment and public health. Consideration of such trade-offs is important in identifying policy and other mechanisms regarding UPF for establishing healthy and sustainable food systems.
Scrutinizing the Expanding Scope of Geographical Indication Protection: A Critical Analysis of the Justifications for the Anti-Evocation Measures
Authors: Song Xinzhe 
Published: October 2023

AbstractThe global trend towards heightened protection for geographical indications (GIs) has been bolstered by the incorporation of anti-evocation provisions in various bilateral and regional trade agreements, primarily led by the European Union (EU). While these anti-evocation measures have raised GI protection to an unprecedented level, they also place limitations on the freedom of expression and competition for other market players. This article conducts a critical analysis of the necessity of those restrictions by evaluating the justifications for implementing anti-evocation protection. Specifically, the analysis centres on the formal justifications put forth by law enforcement authorities and their direct contribution to enforcement errors and inconsistencies. Furthermore, inherent limitations within these justifications are also identified. Clarifying the rationale for anti-evocation protection and establishing a clearly defined scope of protection, substantiated by sound justifications, could effectively mitigate errors and inconsistencies in law enforcement and minimize any undue impact on the public interest. Countries that have adopted or are considering adopting anti-evocation protection, following the EU's lead, should exercise caution to avoid similar pitfalls.
Bristol Type 173 Design, Development and Experiences
Authors: Hafner Raoul 
Published: October 2023

The CHAIRMAN said that it was hardly necessary for him to introduce RAOUL HAFNER who was well known in the helicopter world as Igor Sikorsky or Frank Piasecki He had been engaged in this field for many years and had very many successful designs to his credit His work as Chief Helicopter Designer to the Bristol Aeroplane Company had realised its present climax in the successful flights of the Bristol 173, about which he was going to speak tonightThe Chairman announced that Mr HAFNER had prepared his paper as a joint paper between the Association and the American Helicopter Society Mr HAFNER had been invited to present it to the latter Society on the occasion of their Annual Forum m April The lecture would therefore not be published until it had been delivered in America
Part II Flight Development
Authors: Curties M C 
Published: October 2023

In the first part of this paper the theoretical considerations underlying the design of an automatic control system for helicopters have been discussed This second part describes some flight experiments carried out at R A E , Farnborough In addition to demonstrating the validity of the theory presented, there has emerged from the flying a clear conception of the design features needed in a practical system for every day use by the average helicopter pilotOne of the more interesting aspects of the experimental programme has been in the fact that the results were achieved almost entirely from flight tests At the time when this work was commenced, aerodynamic information of the test aircraft was scanty Thus whilst the theoretical form of the control law was known, the optimum values of the control parameters could only be roughly forecasted and the actual values were obtained in flight
Decca Navigator Installations
Authors: Hinchliffe G 
Published: October 2023

The Decca Company has great faith in the future of the helicopter and we firmly believe that co-operation between our Company and the helicopter industry—both the manufacturing and operating sides of the industry is of the utmost importance We welcome therefore, the opportunity to discuss in the most general, non-technical terms, the problems associated with the installation of Decca equipment on helicoptersI shall refer to the equipment under three headings (1) The aerial, (2) The black boxes, (3) The controls and display, and shall consider the problems associated with each section separatelyBefore proceeding, however, I must point out that there are a vast number of different combinations of Decca Navigator equipment ranging from a simple single chain receiver with flight log display only at a total installed weight of 40 lb to a nine chain receiver with decometers, lane identification and flight log weighing 100 lb
“Aerodynamic Aspects of the Fairey Rotodyne”
Authors: McKenzie K T 
Published: October 2023

The Chairman, in opening the meeting, said that one of the important aspects of aerodynamics was the study of the interaction between two component systems Thus much experimental work was devoted to the investigation of interference effects between, for example, a wing and a body, or one wing and another wing, or a wing with a jet stream issuing from its surface, or the effect of ground proximityIn the rotary wing field, it was necessary to have a knowledge of the aerodynamic interaction between two rotors for the successful design of tandem rotor helicopters With the modern trend for rotorcraft to have fixed wings and become more like aeroplanes, it was necessary now to have an accurate knowledge of the mutual interaction between a wing and a rotor Tonight, this aspect, as well as other aerodynamic aspects of the Fairey Rotodyne, was to be discussed by the lecturer, Mr K T McKenzie
The Development and Future of the Airship
Authors: Evans E E H 
Published: October 2023

IN view of the growing interest in the development of Airships as a step towards the improvement of commercial relationship between the Mother country and the various parts of her far flung Empire, there must be some to whom this subject is of interest, and therefore, as one who has had experience, both in the construction and in the actual flying of several types of Airships, I submit the following brief account of the development of the Airship of to-day and also the possibilities that lie before this type of aircraftThe earliest experiments of a serious character in “Lighter than Air” type of aircraft took place about the year 1776, immediately following the discovery of Hydrogen gas by Cavendish, but it was not until 1783 that the first really successful flight was made by a Frenchman, Professor Charles, who remained in the air for three and three-quarter hours and covered a distance of forty miles in a balloon of his own design, the lifting medium of which was Hydrogen
Analysis of Narrow Bipolar Events Using Mode Decomposition Methods
Authors: Senay Seda , Krehbiel Paul R. , da Silva Caitano L. , Edens Harald E. , Bennecke David , Stanley Mark A. 
Published: October 2023

AbstractMulti‐resolution analysis methods can reveal the underlying physical dynamics of nonstationary signals, such as those from lightning. In this paper we demonstrate the application of two multi‐resolution analysis methods: Ensemble Empirical Mode Decomposition (EEMD) and Variational Mode Decomposition (VMD) in a comparative way in the analysis of electric field change waveforms from lightning. EEMD and VMD decompose signals into a set of Intrinsic Mode Functions (IMFs). The IMFs can be combined using distance and divergence metrics to obtain noise reduction or to obtain new waveforms that isolate the physical processes of interest while removing irrelevant components of the original signal. We apply the EEMD and VMD methods to the observations of three close Narrow Bipolar Events (NBEs) that were reported by Rison et al. (2016, https://doi.org/10.1038/ncomms10721). The ΔE observations reveal the occurrence of complex oscillatory processes after the main NBE sferic. We show that both EEMD and VMD are able to isolate the oscillations from the main NBE, with VMD being more effective of the two methods since it requires the least user supervision. The oscillations are found to begin at the end of the NBEs' downward fast positive breakdown, and appear to be produced by a half‐wavelength standing wave within a weakly‐conducting resonant ionization cavity left behind in the wake of the streamer‐based NBE event. Additional analysis shows that one of the NBEs was likely initiated by an energetic cosmic ray shower, and also corrects a misinterpretation in the literature that fast breakdown is an artifact of NBE‐like events in interferometer observations.
Estimating Sea Surface Salinity in the East China Sea Using Satellite Remote Sensing and Machine Learning
Authors: Liu Jing , Bellerby Richard G. J. , Zhu Qing , Ge Jianzhong 
Published: October 2023

AbstractSea surface salinity (SSS) is a master variable in oceanography and important to understand marine biogeochemical and physical processes. In the East China Sea (ECS), a random forest based regression ensemble model (RF) was developed to estimate the SSS with a spatial resolution of ∼1 km based on a large synchronous data set of in situ SSS observations, MODIS‐derived remote sensing reflectance (Rrs) and sea surface temperature (SST). The model showed the best performance when the Rrs(412), Rrs(488), Rrs(555), Rrs(667), SST and Julian day (JD) were used as inputs, with a root mean square error (RMSE) of 0.84, mean absolute error (MAE) of 0.31 and coefficient of determination (R2) of 0.81 for model training (N = 4,504), and a RMSE of 0.77, MAE of 0.30 and R2 of 0.86 for the model test (N = 1,153). The accuracy of the SSS model was examined using an independent data set during the period of 2020–2022 with a RMSE of 0.66 and MAE of 0.39 (N = 2,151). The interannual and seasonal signal of modeled SSS of the ECS, showed that important drivers of variability are the Changjiang discharge and the East‐Asian monsoon. Applications of the model to other Chinese marginal seas (Yellow and Bohai seas) showed good agreement in distribution patterns when compared with the estimated SSS from NASA Soil Moisture Active Passive. Once more empirical oceanographic data is made available, this robust model can be applied to other regions retraining the model with informed local data sets.