bluuebunny/crossref_metadata_2025_split huggingface dataset:
Heat-vision based drone surveillance augmented by deep learning for critical industrial monitoring
Authors: Lim Do Yeong , Jin Ik Jae , Bang In Cheol 
Published: December 2023

AbstractThis study examines the application of drone-assisted infrared (IR) imaging with vision grayscale imaging and deep learning for enhanced abnormal detection in nuclear power plants. A scaled model, replicating the modern pressurized water reactor, facilitated the data collection for normal and abnormal conditions. A drone, equipped with dual vision and IR cameras, captured detailed operational imagery, crucial for detecting subtle anomalies within the plant's primary systems. Deep learning algorithms were deployed to interpret these images, aiming to identify component abnormals not easily discernible by traditional monitoring. The object detection model was trained to classify normal and abnormal component states within the facility, marked by color-coded bounding boxes for clarity. Models like YOLO and Mask R-CNN were evaluated for their precision in anomaly detection. Results indicated that the YOLO v8m model was particularly effective, showcasing high accuracy in both detecting and adapting to system anomalies, as validated by high mAP scores. The integration of drone technology with IR imaging and deep learning illustrates a significant stride toward automating abnormal detection in complex industrial environments, enhancing operational safety and efficiency. This approach has the potential to revolutionize real-time monitoring in safety–critical settings by providing a comprehensive, automated solution to abnormal detection.
A genome-wide association, polygenic risk score and sex study on opioid use disorder treatment outcomes
Authors: McEvoy Alannah , Chawar Caroul , Lamri Amel , Hudson Jacqueline , Minuzzi Luciano , Marsh David C. , Thabane Lehana , Paterson Andrew D. , Samaan Zainab 
Published: December 2023

AbstractOpioid use disorder continues to be a health concern with a high rate of opioid related deaths occurring worldwide. Medication Assisted Treatments (MAT) have been shown to reduce opioid withdrawal, cravings and opioid use, however variability exists in individual’s treatment outcomes. Sex-specific differences have been reported in opioid use patterns, polysubstance use and health and social functioning. Candidate gene studies investigating methadone dose as an outcome have identified several candidate genes and only five genome-wide associations studies have been conducted for MAT outcomes. This study aimed to identify genetic variants associated with MAT outcomes through genome-wide association study (GWAS) and test the association between genetic variants previously associated with methadone dose through a polygenic risk score (PRS). Study outcomes include: continued opioid use, relapse, methadone dose and opioid overdose. No genome-wide significance SNPs or sex-specific results were identified. The PRS identified statistically significant results (p < 0.05) for the outcome of methadone dose (R2 = 3.45 × 10–3). No other PRS was statistically significant. This study provides evidence for association between a PRS and methadone dose. More research on the PRS to increase the variance explained is needed before it can be used as a tool to help identify a suitable methadone dose within this population.
Consolidation of LVFRT capabilities of microgrids using energy storage devices
Authors: Moheb Aya M. , El-Hay Enas A. , El-Fergany Attia A. 
Published: December 2023

AbstractThe performance and dependability of distribution networks may be enhanced by the incorporation of microgrids (MGs). However, it is necessary to enhance low voltage fault-ride-through (LVFRT), which has the capacity to prevent abrupt grid disconnections during LV occurrences under problematic circumstances. In this study, a control strategy for energy storage elements (ESDs) which includes batteries and supercapacitors is proposed to enhance LVFRT under balanced and unbalanced faults. The MG comprises wind farms and/or photovoltaic arrays. Based on the dynamic simulations using MATLAB/SIMULINK, the ESDs can enhance LVFRT capability. A comparison of the conventional crowbar scheme and ESDs is realized, and the latter has a better performance than the former in retaining the DC-link voltage within satisfactory bounds. For the purpose of maintaining the DC-link voltage at a reference level, the battery stores extra power in the DC-bus of three systems. LVFRT is improved by the crowbar circuit, however the resistance consumes the extra power. Super capacitors (SCs) prevent DC voltage fluctuations, reduce active power oscillations, and hasten system stabilization when present. At an advanced stage of this effort, the coot bird optimizer (CBO) is applied to generate the best gains of bi-directional converter PI-controller and the ESDs ratings to have minimum ripples in the DC-bus voltage and to boost the LVFRT capability of the MGs. The viability of the proposed method based on the CBO’s results is indicated with further validations under different operating scenarios.
In vitro production of naked mole-rats’ blastocysts from non-breeding females using in vitro maturation and intracytoplasmic sperm injection
Authors: Simone Raffaella , Čižmár Daniel , Holtze Susanne , Michel Geert , Sporbert Anje , Okolo Charlotte , Hildebrandt Thomas B. 
Published: December 2023

AbstractThe African naked mole-rat (Heterocephalus glaber) is an attractive model for cancer and aging research due to its peculiar biological traits, such as unusual long life span and resistance to cancer. The establishment of induced pluripotent stem cells (iPSCs) would be a useful tool for in vitro studies but, in this species, the reprogramming of somatic cells is problematic because of their stable epigenome. Therefore, an alternative approach is the derivation of embryonic stem cells from in vitro-produced embryos. In this study, immature oocytes, opportunistically retrieved from sexually inactive females, underwent first in vitro maturation (IVM) and then in vitro fertilization via piezo-intracytoplasmic sperm injection (ICSI). Injected oocytes were then cultivated with two different approaches: (i) in an in vitro culture and (ii) in an isolated mouse oviduct organ culture system. The second approach led to the development of blastocysts, which were fixed and stained for further analysis.
On the potential of transfer entropy in turbulent dynamical systems
Authors: Massaro Daniele , Rezaeiravesh Saleh , Schlatter Philipp 
Published: December 2023

AbstractInformation theory (IT) provides tools to estimate causality between events, in various scientific domains. Here, we explore the potential of IT-based causality estimation in turbulent (i.e. chaotic) dynamical systems and investigate the impact of various hyperparameters on the outcomes. The influence of Markovian orders, i.e. the time lags, on the computation of the transfer entropy (TE) has been mostly overlooked in the literature. We show that the history effect remarkably affects the TE estimation, especially for turbulent signals. In a turbulent channel flow, we compare the TE with standard measures such as auto- and cross-correlation, showing that the TE has a dominant direction, i.e. from the walls towards the core of the flow. In addition, we found that, in generic low-order vector auto-regressive models (VAR), the causality time scale is determined from the order of the VAR, rather than the integral time scale. Eventually, we propose a novel application of TE as a sensitivity measure for controlling computational errors in numerical simulations with adaptive mesh refinement. The introduced indicator is fully data-driven, no solution of adjoint equations is required, with an improved convergence to the accurate function of interest. In summary, we demonstrate the potential of TE for turbulence, where other measures may only provide partial information.
Impact of a virtual educational intervention on knowledge and awareness of biomedical waste management among Peruvian dental professionals
Authors: Cayo-Rojas César , Briceño-Vergel Gissela , Córdova-Limaylla Nancy , Huamani-Echaccaya José , Castro-Mena Manuel , Lurita-Córdova Paolo , Bermúdez-Mendoza Judit , Allen-Revoredo Clifford , Torres-Vásquez Jorge , Ladera-Castañeda Marysela 
Published: December 2023

AbstractWaste from healthcare is a significant global issue, with around 85% of it being common waste and the remaining 15% being hazardous waste that is infectious and toxic. Dentistry uses various materials that create a substantial amount of biomedical waste capable of impacting the environment. Therefore, the purpose of this study was to assess the effects of a virtual educational program on the knowledge and awareness of dental material recycling and reuse, as well as biomedical waste management, among dental professionals in Peru. The current study was a longitudinal and quasi-experimental evaluation of 165 dentists from Peru. A validated questionnaire consisting of 30 items was administered at three different intervals (pre-test, immediate post-test, and 14-day post-test). Statistical analysis was conducted using the Mann Whitney U and Kruskal Wallis H tests to compare scores between categories of each sociodemographic variable, and the Cochrane’s Q and Friedman test was used for related measures comparison. A significance level of p < 0.05 was considered. When comparing the percentage of correct responses regarding recycling and reuse of dental materials and biomedical waste management between the pre-test and the immediate post-test, a significant improvement in knowledge was observed for most of the questionnaire items (p < 0.05). At 14 days after the test, those who studied at a private university, unmarried, bachelors, non-specialists, non-teachers and have less than 10 years of professional experience did not did not retain knowledge on biomedical waste management (p < 0.05) or recycling and reusing dental materials (p < 0.05) to a significant extent. There was a significant enhancement in dentists' knowledge and awareness of managing biomedical waste, recycling, and reusing dental materials following the educational intervention. This improvement was observed across all sociodemographic variables considered in the study. However, this knowledge was not retained beyond two weeks for those who studied at a private university, unmarried, bachelor, with no specialty, non-teachers and with less than 10 years of professional experience. Government authorities should encourage oral health professionals to conduct research with educational interventions focused on improving and evaluating the sustainability and environmental impact of dental practices. This will enable professionals to better understand, control and evaluate the consequences of their practical work.
The centrosomal protein 131 participates in the regulation of mitochondrial apoptosis
Authors: Renaud Clotilde C. N. , Trillet Kilian , Jardine Jane , Merlet Laura , Renoult Ophélie , Laurent—Blond Mélanie , Catinaud Zoé , Pecqueur Claire , Gavard Julie , Bidère Nicolas 
Published: December 2023

AbstractCentriolar satellites are multiprotein aggregates that orbit the centrosome and govern centrosome homeostasis and primary cilia formation. In contrast to the scaffold PCM1, which nucleates centriolar satellites and has been linked to microtubule dynamics, autophagy, and intracellular trafficking, the functions of its interactant CEP131 beyond ciliogenesis remain unclear. Using a knockout strategy in a non-ciliary T-cell line, we report that, although dispensable for centriolar satellite assembly, CEP131 participates in optimal tubulin glycylation and polyglutamylation, and microtubule regrowth. Our unsupervised label-free proteomic analysis by quantitative mass spectrometry further uncovered mitochondrial and apoptotic signatures. CEP131-deficient cells showed an elongated mitochondrial network. Upon cell death inducers targeting mitochondria, knockout cells displayed delayed cytochrome c release from mitochondria, subsequent caspase activation, and apoptosis. This mitochondrial permeabilization defect was intrinsic, and replicable in vitro with isolated organelles. These findings extend CEP131 functions to life-and-death decisions and propose ways to interfere with mitochondrial apoptosis.
Benthic microbial biogeographic trends in the North Sea are shaped by an interplay of environmental drivers and bottom trawling effort
Authors: Bonthond Guido , Beermann Jan , Gutow Lars , Neumann Andreas , Barboza Francisco Rafael , Desiderato Andrea , Fofonova Vera , Helber Stephanie B , Khodami Sahar , Kraan Casper , Neumann Hermann , Rohde Sven , Schupp Peter J 
Published: December 2023

Abstract
Microbial composition and diversity in marine sediments are shaped by environmental, biological, and anthropogenic processes operating at different scales. However, our understanding of benthic microbial biogeography remains limited. Here, we used 16S rDNA amplicon sequencing to characterize benthic microbiota in the North Sea from the top centimeter of 339 sediment samples. We utilized spatially explicit statistical models, to disentangle the effects of the different predictors, including bottom trawling intensity, a prevalent industrial fishing practice which heavily impacts benthic ecosystems. Fitted models demonstrate how the geographic interplay of different environmental and anthropogenic drivers shapes the diversity, structure and potential metabolism of benthic microbial communities. Sediment properties were the primary determinants, with diversity increasing with sediment permeability but also with mud content, highlighting different underlying processes. Additionally, diversity and structure varied with total organic matter content, temperature, bottom shear stress and bottom trawling. Changes in diversity associated with bottom trawling intensity were accompanied by shifts in predicted energy metabolism. Specifically, with increasing trawling intensity, we observed a transition toward more aerobic heterotrophic and less denitrifying predicted metabolism. Our findings provide first insights into benthic microbial biogeographic patterns on a large spatial scale and illustrate how anthropogenic activity such as bottom trawling may influence the distribution and abundances of microbes and potential metabolism at macroecological scales.
Cardiometabolic and renal phenotypes and transitions in the United States population
Authors: Lhoste Victor P. F. , Zhou Bin , Mishra Anu , Bennett James E. , Filippi Sarah , Asaria Perviz , Gregg Edward W. , Danaei Goodarz , Ezzati Majid 
Published: December 2023

AbstractCardiovascular and renal conditions have both shared and distinct determinants. In this study, we applied unsupervised clustering to multiple rounds of the National Health and Nutrition Examination Survey from 1988 to 2018, and identified 10 cardiometabolic and renal phenotypes. These included a ‘low risk’ phenotype; two groups with average risk factor levels but different heights; one group with low body-mass index and high levels of high-density lipoprotein cholesterol; five phenotypes with high levels of one or two related risk factors (‘high heart rate’, ‘high cholesterol’, ‘high blood pressure’, ‘severe obesity’ and ‘severe hyperglycemia’); and one phenotype with low diastolic blood pressure (DBP) and low estimated glomerular filtration rate (eGFR). Prevalence of the ‘high blood pressure’ and ‘high cholesterol’ phenotypes decreased over time, contrasted by a rise in the ‘severe obesity’ and ‘low DBP, low eGFR’ phenotypes. The cardiometabolic and renal traits of the US population have shifted from phenotypes with high blood pressure and cholesterol toward poor kidney function, hyperglycemia and severe obesity.
Against a nation state of emergency: how climate emergency politics can undermine climate justice
Authors: Osborne Natalie , Carlson Anna 
Published: December 2023

AbstractIn recent years, eco-activist groups, academics, industry groups, governments, and other organisations have called for, or declared, a climate emergency. These declarations offer discursive and political consent for emergency climate actions. Without refuting the urgent need to take meaningful action to limit and adapt to climate change, in this paper we argue emergency declarations can have effects that may ultimately work against climate justice. To do this, we contextualise climate injustice as part of a much longer history of colonial racial capitalism, and suggest that discourses and declarations of emergency often serve as tools through which the political conditions and histories that shape and sustain injustices, including environmental and climate injustices, are erased. Working from the present conjuncture and the aftermath of the ‘crisis’ responses to the COVID-19 pandemic, we show how discourses of emergency and crisis serve as tools through which the coercive and controlling powers of the state are sustained, maintained, and legitimised. Reading across a vast history of crisis colonialism, we show how emergency measures enable the expansion, consolidation, and militarisation of colonial settler states, linking existing anticolonial critiques with ideas of disaster capitalism and fossil fascism to offer a cautionary intervention into movements for climate action that persist with logics and discourses of emergency and crisis. We warn that declarations of emergency are not only ineffective tools in the pursuit of climate justice, but may be actively dangerous.
Rehabilitation Treatment Specification System for Voice Therapy: Application to Everyday Clinical Care
Authors: Wolfberg Jeremy , Whyte John , Doyle Patricia , Gherson Shirley , Muise Jason , Petty Brian , Tolejano Carol Jorgensen , Hillman Robert E. , Stadelman-Cohen Tara , Van Stan Jarrad H. 
Published: December 2023

Purpose:
Rehabilitation intervention descriptions often do not explicitly identify active ingredients or how those ingredients lead to changes in patient functioning. The Rehabilitation Treatment Specification System (RTSS) provides guidance to identify the critical aspects of any rehabilitation therapy and supported the development of standardly named ingredients and targets in voice therapy (Rehabilitation Treatment Specification System for Voice Therapy [RTSS-Voice]). This study sought to test the content validity of the RTSS-Voice and determine if the RTSS-Voice can be used to identify commonalities and differences in treatment (criterion validity) across clinicians in everyday clinical practice.

Method:
Five speech-language pathologists from different institutions videotaped one therapy session for 59 patients diagnosed with a voice or upper airway disorder. Specifications were created for each video, and iterative rounds of revisions were completed with the treating clinician and two RTSS experts until consensus was reached on each specification.

Results:
All 59 sessions were specified without the addition of any targets or ingredients. There were two frequent targets: (a) increased volition and (b) decreased strained voice quality. There were three frequent ingredients: (a) information regarding the patient's capability and motivation to perform a therapeutic behavior, (b) knowledge of results feedback, and (c) opportunities to practice voicing with improved resonance and mean airflow. Across sessions treating vocal hyperfunction, there was large variability across clinicians regarding the types and number of treatment components introduced, types of feedback provided, and vocal practice within spontaneous speech and negative practice.

Conclusions:
The RTSS and the RTSS-Voice demonstrated strong content validity, as they comprehensively characterized 59 therapy sessions. They also demonstrated strong criterion validity, as commonalities and differences were identified in everyday voice therapy for vocal hyperfunction across multiple clinicians. Future work to translate RTSS principles and RTSS-Voice terms into clinical documentation can help to understand how clinician and patient variability impacts outcomes and bridge the research–practice gap.

Supplemental Material:

https://doi.org/10.23641/asha.24796875
Coordinating Words and Sentences: Detecting Age-Related Changes in Language Production
Authors: Sung Jee Eun , Jo Eunha , Choi Sujin , Lee Jiyeon 
Published: December 2023

Purpose:
The purpose of this study was to examine whether older adults exhibit reduced abilities in coordinating lexical retrieval and syntactic formulation during sentence production and whether an individual's working memory capacity predicts age-related changes in sentence production.

Method:
A total of 124 Korean-speaking individuals (79 young and 45 older adults) completed a lexical priming sentence production task. The participants described a target picture (a dog biting a monkey) after reading either an agent (dog) or a theme (monkey) prime word. The proportion of passive sentences was used as the dependent variable.

Results:
When the theme noun was primed, older adults produced fewer passive sentences than young adults. Working memory tasks significantly predicted individual differences in the sentence production of older adults.

Conclusions:
With aging, the ability to efficiently formulate syntactic structures in coordination with varying lexical information declines. Among older adults, age-related changes in these sentence production processes are associated with reduced working memory. Our constrained language production task is sensitive to detecting aging effects.
Under the Surface: Rhoticity and Relevance in the Song “Surface Pressure” From Disney's
Encanto
Authors: Lockenvitz Sarah , Brooks Avery 
Published: December 2023

Purpose:

The song “Surface Pressure” from the Disney film
Encanto
is believed to have a relatively high number of opportunities for production practice of rhotic speech sounds in comparison to conversational tasks. Given the effectiveness of meaningful activities in speech-language intervention, incorporation of this song into treatment has the potential to benefit speech-disordered children.

Method:
Transcription of “Surface Pressure” using the International Phonetic Alphabet was completed by two independent transcribers, and a consensus was reached on all discrepancies (94.8% consistency). Frequency of occurrence for different rhotic speech sounds was calculated.

Results:
The song “Surface Pressure” contains a proportionally high number of the uncommon American English stressed and unstressed schwars at 5.32% of the total phonemes in the entirety of the song, compared to 2.21% in conversational American English. Over 9% of the total phonemes are characterized by some degree of rhoticity, compared to 6.08% in conversation.

Conclusions:
The construction of “Surface Pressure” creates an accessible and authentic opportunity for targeting errored productions of rhotic speech sounds in a potentially culturally and socially relevant way. Similar analyses could justify the use of other distinctive children's movie songs in place of more traditional methods of elicitation for various speech disorder assessment and intervention needs, all with the objective of offering meaningful, authentic, and relevant opportunities for desired productions.