bluuebunny/crossref_metadata_2025_split huggingface dataset:
Whole Genome Sequencing and Analysis of Benzo(a)pyrene Degrading Bacteria Bacillus cereus ZR72-1
Authors: tuerxun Dilibaier , zhang rui , qin yanan , jin aofei , tan lirong , yang zhuonan , duo zhixian 
Published: February 2024

Abstract
Background
Benzo (a) pyrene produced by food during high-temperature process enters the body through ingestion, which causes food safety issues to the human body. In order to alleviate the harm of foodborne benzo (a) pyrene to human health, a strain that can degrade benzo (a) pyrene was screened from Kefir, a traditional fermented product in Xinjiang.
Results
Bacillus cereus ZR72-1 is a Gram-positive bacteria sourced from XinJiang traditional fermented product Kefir, under Benzo(a)pyrene stress conditions, there was 69.39% degradation rate of 20 mg/L Benzo(a)pyrene by strain ZR72-1 after incubation for 72 h. The whole genome of ZR72-1 sequenced using PacBio sequencing technology was reported in this study. The genome size was 5754801 bp and a GC content was 35.24%, a total of 5719 coding genes were predicted bioinformatically. Through functional database annotation, it was found that the strain has a total of 219 genes involved in the transportation and metabolism of hydrocarbons, a total of 9 metabolic pathways related to the degradation and metabolism of exogenous substances, and a total of 67 coding genes.
Conclusions
According to the KEGG database annotation results, a key enzyme related to Benzo(a)pyrene degradation, catechol 2,3-dioxygenase, was detected in the genome data of Bacillus cereus ZR72-1, encoding genes dmpB and xylE, respectively; There are also monooxygenases and dehydrogenases. Therefore, it can be inferred that this strain mainly degrades Benzo(a)pyrene through Benzoate metabolic.
Stepped psychological care in post-stroke aphasia: Feasibility protocol to evaluate the co- designed “Kalmer” online relaxation intervention
Authors: El-Helou Rebecca , Ryan Brooke , Hilari Katerina , Kneebone Ian 
Published: February 2024

Abstract
Background: People with stroke are at greater risk of experiencing depression and anxiety. The prevalence of these difficulties in those with the communication disorder aphasia after stroke is even higher. Relaxation training is recommended as part of stepped care for mental health difficulties for those with stroke. The potential impact of the online co-designed Kalmer relaxation intervention and thus its place within stepped care for people with post stroke aphasia is unknown.
Methods/design: This study will determine the feasibility and potential efficacy of the Kalmer relaxation intervention on people with post stroke aphasia and who met the cut off on screening instruments for anxiety and/or depression. Primary outcomes will be assessed using two observer rated scales; the Behavioural Outcomes of Anxiety (BOA) and the Stroke Aphasia Depression Questionnaire - 10 item (SADQ-10). A case series design will utilise a multiple baseline procedure. Up to 12 participants will be recruited. Consent procedures modified for those with aphasia will be employed. The Reliable Change Index will be used to determine the interventions impact on anxiety and depressive symptoms. Participants will be followed-up at 3- and 6-month intervals.
Discussion: This study represents the first known evaluation of the online co-designed Kalmer relaxation intervention program. The results will have implications for recommending its inclusion as a recommended treatment at Step 2 of mental health care for people with aphasia after stroke.
Hexokinase 2 aggravates airway inflammation in experimental asthma by regulating airway epithelial cell death
Authors: Tian Zhen , Wang Shanshan , Fan Yan , Li Boyu , Zheng Hongyan , Lu Yanjiao , Huang Zhenli , Wang Meijia , Zhang Jixian , Zhao Jianping , Xie Jungang 
Published: February 2024

Abstract
Background
Asthma is a prevalent inflammatory lungs disease which poses a substantial global health and economic burden. Abnormal glucose metabolism in asthmatic patients has recently attracted much attention. As a key enzyme in glycolysis, the participation of Hexokinase 2(HK2) in the disease course of asthma has not been fully understudied.
Methods
In an asthma mouse model, the expression levels of Hexokinase 2 (HK2) were validated, and a mouse model with HK2 specifically knocked out in airway epithelial cells was created to investigate the role of HK2 in bronchial asthma. In vitro cellular experiments involved the overexpression and knockdown of HK2 to study its role and related mechanisms in airway epithelial cell death and airway inflammation in bronchial asthma.
Results
HK2 is found to have increased expression in both mouse asthma models, especially showing elevated expression in airway epithelial cells. Mice that specifically lacked HK2 in their airway epithelium were observed to be protected from cell death and inflammation during asthma. Moreover, airway epithelial cells treated with HK2 overexpression exacerbated cell death and elevated the expression of inflammatory interleukins, conversely after silencing HK2 in vitro, cell death and inflammatory interleukins expression were greatly improved. We further surmise that HK2 might be involved in the regulation of airway epithelial cell death and airway inflammation through PPIF and VDAC1. Furthermore, the treatment of mice with HK2 inhibitor, 2-DG, markedly attenuated the inflammatory cell infiltration in the pulmonary tissues.
Conclusion
HK2 plays a crucial role in the occurrence and progression of bronchial asthma, being involved in airway epithelial cell death and airway inflammation.
Can multinationals withstand growing trade barriers?
Authors: Ghodsi Mahdi , Vujanovic Nina , Landesmann Michael 
Published: February 2024

Abstract

Multinational enterprises (MNEs) are increasingly dealing with challenges shaped by the new geopolitical and trade environments. Besides traditional tariffs, exporting firms need to comply with regulatory non-tariff measures (NTMs) in the form of technical barriers to trade (TBTs) and sanitary and phytosanitary (SPS) measures. Although trade costs associated with these policy measures affect all firms, implications could be multifaceted for multinationals that base their international activities on exporting and importing and are important for the formation of global supply chains. Applying Poisson pseudo maximum likelihood to the unique Orbis dataset of firms on multinational subsidiaries, we show that NTMs pose a greater challenge to MNEs’ subsidiaries’ activity and performance than tariffs do. High-tech manufacturing subsidiaries of foreign MNEs are particularly vulnerable to these NTMs, as they suffer higher regulatory losses. However, multinational affiliates that have higher productivity, those with full foreign ownership representation, those that are embedded within a larger international network of subsidiaries, and those that are located in trading partners with deep preferential trade agreements can turn these trade challenges to their advantage. Our results have important implications for policy makers regulating trade in goods.
JEL: F23, F211, F12, F13, F15, C55
Debunking Rumors: Exploring the truth in a sea of social Whispers
Authors: Ma Manfu , Zhang Cong , Li Yong , Chen Jiahao , Wang Xuegang 
Published: February 2024

Abstract

While social media platforms promote people's information exchange and dissemination, they also make rumors spread rapidly on online platforms. Therefore, how to detect rumors quickly, timely and accurately has become a hot topic for scholars in related fields. Traditional deep learning models ignore the relationship and topology between nodes in the rumor detection task, and use fixed weights or mean aggregation strategies in the feature aggregation process, which fail to capture the complex interactions between nodes and the dynamics of information propagation, limiting the accuracy and robustness of the rumor detection model. To address the these problems, we propose a location-aware weighted GraphSAGE rumor detection model GSMA. we first introduce an attention mechanism that dynamically assigns different attention weights to different neighboring nodes for different degrees of aggregation, improving GraphSAGE's strategy of using mean-value aggregation for all neighboring nodes during the aggregation process; second, we introduce a modulated location encoding into the model and encode the position information of nodes into the features to improve the model's ability to perceive the relative position and order of nodes; finally, the post text sentiment is incorporated into the features to provide additional semantic information for the model as a way to achieve rumor detection in microblogging platforms. Experiments show that the accuracy of the GSMA model on Ma-Weibo and Weibo23 reaches 97.43% and 97.55%, which is an improvement of 1.11% and 0.77% compared to the benchmark GraphSAGE, and all the evaluation metrics are also improved compared to other optimal rumor detection models.
A network science-based model for the evolution of environmental mass events
Authors: Xue-ting Qi , Bu Fanliang 
Published: February 2024

Abstract

The characteristics of environmental group events vary significantly, and the evolution law is profound and complex. It is essential to establish an evolutionary model to reasonably analyze environmental group events, and based on the network science theory using limited topological information of event meta-nodes, the evolutionary process of environmental group events can be effectively simulated, but the existing evolutionary model of environmental group events is limited by macroscopic evaluation indexes, and the same similarity calculation index is used to describe the evolutionary fluctuations of all event nodes. The differences in node evolutionary fluctuations in different group-based events are neglected, which is not conducive to enhancing the performance of the model on evolutionary processes among different environmental group-based events. To enhance the accuracy and sensitivity of the model, this paper proposes a simulation method NodeAL based on network science theory for environmental group sex events. specific work is as follows: (1) propose SimDecide algorithm to quantify evolutionary fluctuations, fit environmental group sex events under different similarity calculation index algorithms, and determine the best similarity of environmental group sex event nodes in different periods according to the results (2) proposed MicroEvol algorithm to quantitatively evaluate the overall evolutionary impact of environmental mass events (3) conducted comparative experiments in real environmental mass events, and the experimental results show that NodeAL has a better fit to each stage of environmental mass event evolution, which is more conducive to the simulation of environmental mass events, making it a decision maker and researcher in the management field This makes it a valuable tool for decision-makers and researchers in the management field.
Do Intensıve Care Nurses Experıence Moral Dıstress Whıle Carıng for COVID-19 Patıents and are Theır Carıng Behavıors Affected?: A Descriptive Study
Authors: Bulmuş Esra , Torun Serap 
Published: February 2024

Abstract

Background
Examining the effect of the level of moral distress experienced by nurses on their care behaviors is important since it has a positive effect on health care services and patient satisfaction. This study was conducted to examine the effect of moral distress experienced by nurses working in intensive care units while caring for COVID-19 patients on their care behaviors.
Method
The universe of the study consisted of 142 nurses working in COVID-19 intensive care units in a university hospital in Adana, and the study sample consisted of 104 nurses who agreed to participate in the study between April and July 2022. For data collection, Personal Information Form, Moral Distress Scale (MDS) and Caring Behaviors Scale (CBS-24) were used. In statistical analysis; frequency, number and percentage values, independent Student-t test and Mann Whitney U test were used in two-group variables, and simple regression analysis was used to examine the relationship between the two scales. A statistical significance value of p < 0.005 was accepted.
Findings:
The mean MDS score was 91.75 ± 48.80 and the mean CBS-24 score was 5.49 ± 0.45. According to simple regression analysis, there was no statistically significant relationship between the total and subscale scores of MDS and CBS-24. In the study, it was found that the variables of age, professional experience, staffing, and experiencing moral distress in the way of managing patient care in the institution statistically affected the mean scores of the "knowledge-skill" subscale of CBS-24 (p < 0.05), and those who wanted to resign from nursing at the time of the study had a higher mean total score of MDS (p < 0.05).
Conclusion
As a result of the study, it was found that nurses had low level of moral distress and high level of positive caring behaviors.
Safety and accuracy assessment of static computer assisted localized piezoelectric alveolar decortication: an in vitro study
Authors: Lara-Muros María , Camps-Font Octavi , Vilarrasa Javi , Vilarrasa Jordi , Mir-Mari Javier , Figueiredo Rui , Valmaseda-Castellón Eduard 
Published: February 2024

Abstract

Objectives
To assess the safety and accuracy of static computer assisted corticotomy surgery (sCACS) in comparison with freehand piezocision.
Material and methods
A randomized in vitro study was conducted. A total of 260 interradicular corticotomies were performed in 20 identical printed models. dsCACS was performed in half of the models, while the rest underwent freehand localized decortication. Accuracy was measured in the three spatial axes by overlapping the digital planning with a previous cone-beam computed tomography (CBCT) scan of the patient and a postoperative CBCT of the models. Safety was determined as the number of damaged root surfaces. Descriptive and bivariate analyses were performed.
Results
Freehand corticotomies increased the likelihood of iatrogenic root damage 2.21-fold (95%CI: 1.30 to 3.77; p = 0.004). Both groups showed some degree of deviation compared to digital planning. Nevertheless, the accuracy of sCACS was significantly greater in sagittal (B = -0.21 mm, 95%CI: -0.29 to -0.12; p < 0.001), axial (B = -0.32 mm, 95%CI: -0.48 to -0.18; p < 0.001) and angular deviation (B = -2.02º; 95%CI: -2.37 to -1.66; p < 0.001) compared to freehand surgery, with the exception of depth.
Conclusions
The precision and safety of sCACS are greater than that of the freehand technique.
Clinical relevance:
Corticotomies are performed in crowded areas where there is usually space limitation. Clinicians should consider the systematic use of surgical guides, since minimal deviations can cause iatrogenic root damage in areas where malocclusions are present.
A simple and efficient Agrobacterium tumefaciens mediated transgenic system for tetraploid potato cultivar Desiree
Authors: Xu Chunjiang , Qi Lipan , Chang Shiwei , Yuan Pingping , Zhang Zhenxin , Shan Youjiao , Magembe Eric , Kear Philip , Feng Yan , Li Yafei , Ji Yihong , Wang Lei , Li Jieping 
Published: February 2024

Abstract
As the fourth staple food crop in the world, potatoes can provide enough energy, protein, and nutrients necessary for humans. However, the population growth and negative effects of climate change call for improved potato yields and resilience. Genetic engineering is a convenient way to improve potato varieties and create new germplasm resources. Agrobacterium tumefaciens mediated transformation is a stable and widely used method for genetic improvement. In this study, a simple and efficient transgenic system was built by testing different potato materials, explants type, selection medium, selection agent, A. tumefaciens EHA105 strain carried different vectors. The results shown this simple system produced positive transformed seedlings in about 40 days. The lower ploidy change ratio for tetraploid variety Desiree compared to diploid recipient. Both SEG and SE could function as a single regeneration medium. Leaf discs explants is eligible. The concentration of 20μg/L is suitable for chlorsulfuron selection. The positive transgenic efficiency of tetraploid recipient Desiree is up to 68.79%, This simple and fast transgenic system provides a powerful tool for supporting basic research on potato functional genes and creating new potato materials for genetic engineering breeding.
Research on Deck-Disposed Scheduling Method of Carrier Aircraft Based on BPSO
Authors: Si WeiChao , Song Chao , Sun Tao , Li Cheng 
Published: February 2024

Abstract

Before taking off, carrier aircraft need to be placed on the battle position of the aircraft carrier flight deck in advance, and different deployment schemes have an important impact on the entire departure process. Based on this background, this paper studies the carrier aircraft deployment scheduling problem. Firstly, the mathematical model of carrier aircraft deployment and scheduling is analyzed and proposed. The carrier aircraft fleet deployment and scheduling problem is transformed into a multiobjective optimization problem with constraints to find the minimum solution. Secondly, taking Nimitz class aircraft carrier as the research object, the digital modeling of aircraft carrier battle position, the constraint and target analysis, and the take-off calculation model design are carried out. Thirdly, the aircraft carrier flight deck deployment scheduling algorithm BPSO is designed, which is improved on the basis of PSO and has faster optimization speed and better optimization results. Finally, based on the previous model and BPSO algorithm, taking the Nimitz class aircraft carrier's maximum wave take-off task as an example, the carrier deployment and scheduling simulation analysis is carried out. The simulation results show that the whole method can solve the carrier aircraft deployment scheduling problem well.
CLC number: TP3; V24
Supracluster Rotaxanes with Adaptive Al8 Macrocycle for Tunable Optical Limiting
Authors: Fang Wei-Hui , Liu Ya-Jie , Zheng Chan , Wang Di , Xiao Han , Wang Zirui , Zhang Cheng-Yang , Zhang Xue-Zhen , Wang San-Tai , Chen Ran-Qi , Zhang Jian 
Published: February 2024

Abstract
Mechanically interlocked molecules like rotaxane have attracted considerable attention in supramolecular chemistry and have been shown useful for the construction of molecular machines. Metal coordination chemistry plays an important role to expand the rotaxanes and immobilize the ring components to the axial molecules. Although many types of macrocycles have been extensively used to make rotaxanes, those based on metal-organic macrocycles are relatively undeveloped. Therefore, there is a large potential for exploring their supracluster assemblies for target properties. Different from the currently limited study on "axle-H···ring” noncovalent binding mode in host-guest inorganic-organic supramolecular chemistry, we herein developed an opposite supracluster assembly pattern naming "ring-H···axles". The key to the success of donor and acceptor role reversal is the use of a flexible Al8 macrocycle: its capsule-shaped cavity with sufficient hydrophobic aromatic inner wall and hydrophilic -OH sites provide an excellent environment to form and adapt to the axles. Such "ring-H···axles" noncovalent binding mode pattern altered the fixed binding mode of ring and axle in reported hybrid inorganic-organic rotaxanes and versatility of the axles involving molecules, metal complexes and infinite metal coordination “strings”. The capsule-shaped Al8 macrocycle acts as a confined reactor demonstrating the directional, stepwise, and controlled assembly process from molecules, metal complexes to metal coordination “strings”, resulting in the isolation from [2]-pseudorotaxane, [2]-rotaxane, to higher-ordered polyrotaxanes. Different from the traditional solution-phase method to make rotaxane, this work provides an atomically precise synthesis route for constructing supracluster rotaxane. Such controlled synthesis in the atomic-level confined cavity provides an excellent platform for property study. A rigid Al8 macrocycle can trap metal centers through electrostatic interaction, while flexible organic ligands can interact with aromatic guests through π···π stacking. Therefore, the heavy metal effect and conjugation effect can be introduced simultaneously to remarkably improve photo-related properties such as optical limiting and third-order nonlinear responses.
Successful treatment of a rare complication of pulmonary vein stenting: atrial rupture and stent detachment: a case report
Authors: yu wei , LI Fajiu , Zhu ziyang , qin wei 
Published: February 2024

Abstract

Pulmonary vein stenosis is a rare disease of Pulmonary vein ablation (PVA). Due to the lack of specific manifestations and inconsistent follow-up, the disease may be misdiagnosed. Severe pulmonary vein stenosis requires intervention. The current main treatment methods are pulmonary vein stent implantation and / or balloon dilation. Such treatment methods have potential serious complications. We report a 61-year-old male patient who was diagnosed with left pulmonary vein occlusion due to repeated hemoptysis pain. Atrial rupture and stent detachment occurred during the intervention. Active intervention during the operation successfully avoided serious consequences.
Effect of Temperature and Humidity on Mechanical Properties and Constitutive Modeling of Pressure- Sensitive Adhesives
Authors: Luo Weiquan , Chen Wenzhen , Liu Dashun , Huang Xiaofeng , Ma Baoguang 
Published: February 2024

Abstract
Pressure-sensitive adhesives (PSAs) are crucial for the structural and functional integrity of flexible devices. This study conducts systematic mechanical tests, including uniaxial tensile, compression, planar shear, and stress relaxation, on PSAs at temperatures ranging from − 25℃ to 85℃ and relative humidity levels from 0–90%. The Ogden model effectively describes the hyperelastic behavior of PSAs under large deformations, as indicated by an R-Square value above 0.97. The results show that temperature markedly affects PSA properties, particularly near the glass transition temperature (Tg), with lower temperatures leading to decreased elasticity and higher temperatures aiding in stress relaxation. Similarly, humidity impacts PSA behavior, increasing elasticity and decreasing stiffness, especially noticeable in stress relaxation tests. These findings highlight the substantial influence of environmental conditions on the material properties of PSAs and underscore the necessity of understanding both hyperelastic and viscoelastic responses for their application in flexible technologies. This research provides critical insights for the optimal utilization of PSAs in the rapidly evolving field of flexible electronics, including OLED displays.