bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extraction of the Global Maximum Power for PV System under PSC Using an Improved PSO Technique
Authors: Nzoundja Fapi Claude Bertin , Tchakounté Hyacinthe , Ndje Martial , Wira Patrice , Kamta Martin 
Published: September 2023

To get the most power out of photovoltaic (PV) panels, PV systems must utilize a maximum power point tracking (MPPT) controller. In partial shading conditions (PSC), the power-voltage (P-V) characteristic of the PV network may show a single global maximum power point (GMPP) and two or more local maximum power points (LMPP). This indicates that the PV cells and panels do not get uniform illumination. As they converge on the maximum power point (MPP) that makes contact first, which is often one of the LMPPs in this scenario, common MPPT approaches like incremental conductance (InC) and perturb and observe (P&O) are unable to distinguish between a GMPP and LMPPs. In this paper, the extraction of the GMPP of the PV system under PSC based on a suggested particle swarm optimization (PSO) approaches is presented. The particularity of the suggested approach is that it takes into account the calculation of the position of each particle as a function of the duty cycle and the global maximum power. Results on the performance of the suggested PSO method show an advantage over the conventional PSO and the commonly used traditional P&O method. The suggested PSO technique offer better performance in terms of global power extracted, ripple rate of the power and efficiency.
Building Disaster Resilient Tourism through Strengthening Disaster Management Strategies in Batu City
Authors: Praditya Editha , Ali Yusuf , Surjaatmadja Surachman , Duarte Rui , Suprapto Firre An , Saragih Herlina Juni Risma 
Published: September 2023

Indonesia has a high intensity of disaster events. The high incidence of disasters in Indonesia has had a detrimental impact on several sectors, one of which is the tourism sector. This study was conducted to find out actors who play a role in disaster management strategy and their relation to national defense. This study used QGIS software, MICMAC, and MACTOR for analysis. MICMAC analysis emphasizes factors or variables, and then MACTOR emphasizes actors. This research found that the institutional capacity between institutions in Batu City was good, but still needed to be improved. The role of actors in improving disaster management in tourism areas in Batu City is very crucial, especially BPBD and DLH as actors who influence other actors on strategy and disaster management in Batu City. The role of actors in disaster management through risk mapping, preparing emergency response plans, and involving the community in prevention efforts are important actions in disaster management. The success of these efforts will contribute to overall national security and stability. This condition led to the involvement of the Indonesian National Armed Forces (TNI) in emergency disaster response operations.
PELATIHAN DASAR MICROSOFT OFFICE WORD GUNA MENINGKATKAN KUALITAS KINERJA PERANGKAT DESA PALINGKAU JAYA, KECAMATAN KAPUAS MURUNG, KABUPATEN KAPUAS, KALIMANTAN TENGAH
Authors: Bhaskara Aribawa Ajid , Makhrian Andy 
Published: September 2023

Seiring dengan perkembangan era teknologi dizaman sekarang, memahami teknologi informasi dan komputer sangat membantu dalam kehidupan sehari-hari, terutama dalam dunia kerja. Kegiatan pelatihan Microsoft Office Word ini bertujuan untuk membekali keterampilan perangkat Desa Palingkau Jaya dalam penggunaan komputer khususnya yang berkaitan dengan sistem pelayanan administrasi masyarakat. Didapati bahwa sebagian besar perangkat Desa Palingkau Jaya tidak menguasai penggunaan standar program yang ada di komputer khususnya Microsoft Office Word. Salah satu cara untuk meningkatkan kemampuan perangkat Desa Palingkau Jaya dalam peradministrasian desa yaitu dengan cara memberikan program pelatihan dasar Microsoft office word. Pelatihan ini bisa menjadi salah satu cara untuk meningkatkan kemampuan perangkat desa. Program pelatihan ini menggunakan metode berupa pemberian materi mengenai dasar-dasar Microsoft office word dan praktek secara langsung. Diharapkan dengan diadakannya program pelatihan ini dapat mengembangkan pengetahuan perangkat desa Palingkau Jaya dalam mengoperasikan Microsoft office word dan memaksimalkan kinerja Perangkat Desa Palingkau Jaya, Kecamatan Kapuas Murung, Kabupaten Kapuas dalam melayani masyarakat.
Kata Kunci: Pelatihan, MS Word, Palingkau Jaya

ABSTRACT
MICROSOFT OFFICE WORD BASIC TRAINING TO IMPROVE THE PERFORMANCE OF PLINGKAU JAYA VILLAGE ADMINISTRATOR, KAPUAS MURUNG SUB-DISTRICT, KAPUAS DISTRICT, CENTRAL KALIMANTAN. Along with the times, of today's technology, understanding information technology and computers is very helpful in everyday life, especially in the world of work. This Microsoft Office Word activity aims to train the skills of the Desa Palingkau Jaya apparatus in using computers, especially those related to the community administration service system. It was found that most of the apparatus of the Desa Palingkau Jaya did not master the use of standard programs on computers, especially Microsoft Office Word. One way to improve the ability of the Desa Palingkau Jaya apparatus in administration is by providing a basic Microsoft office word training program. This training can be one way to improve the capacity of village officials. This program uses the method of providing material on basic Microsoft office word training and hands-on practice. It is hoped that by holding this training program, it is hoped that this training program will be able to develop the knowledge tools of the Desa Palingkau Jaya in operating Microsoft office word and maximize the performance of the Desa Palingkau Jaya, Kecamatan Kapuas Murung, Kabupaten Kapuas in serving the community.
Keywords: Training, MS Word, Palingkau Jaya
PEMBERDAYAAN MASYARAKAT MELALUI PROGRAM EDUKASI PENANAMAN TANAMAN OBAT KELUARGA (TOGA) DI DESA PURWODADI, KECAMATAN WAY SULAN, KABUPATEN LAMPUNG SELATAN
Authors: Sylvia Teny , Denisman Pasaribu Tri , Bagas Andika Mochamad , Rizqy Harahap Miftah , Shorim Ar Giffary Muhammad , Alfarisi Salman , Putri Khairunnisa Zalfa , Michael Sarumaha Joseph , Febila Nasikin Jesika , Novalendra Gaizka , Komala Dewi Julia , Alfaridho Muhammad , Bima Sobirin Muhammad , Fitriyani Nefa , Fuady Aziz Zakian Nur , Desty Safitri Regif 
Published: September 2023

Pengabdian dalam bentuk pemberdayaan masyarakat dilakukan di Desa Purwodadi dengan skema kegiatan KKN-PPM yang dilaksanakan oleh kelompok 138. Pada pelaksanaan pengabdian masyarakat ini, salah satu aspek yang sangat penting dalam kehidupan manusia adalah kesehatan sehingga salah satu program kerja utama adalah Penanaman Tanaman Obat Keluarga (TOGA). Tanaman obat keluarga adalah jenis tanaman yang dapat ditanam di lahan pekarangan rumah yang dipergunakan untuk memenuhi keperluan obat-obatan keluarga yang dapat dibuat sendiri tanpa campuran kimia. Tanaman obat keluarga bertujuan agar masyarakat sehat dengan memanfaatkan TOGA sebagai sumber penyediaan obat-obatan tradisional dan masyarakat mendapatkan pertolongan pertama dengan memanfaatkan tanaman yang ada di sekitarnya. Hal ini karena pada dasarnya setiap tanaman memiliki manfaatnya masing-masing. Metode yang dilakukan dari kegiatan penanaman tanaman obat keluarga ini dimulai dari sosialisasi, diskusi dan tanya jawab, gotong royong, monitoring, dan evaluasi. Berdasarkan hasil kegiatan penanaman tanaman obat keluarga tersebut didapat indikator capaian yaitu pemahaman masyarakat tentang jenis-jenis tanaman obat keluarga yang bermanfaat untuk kesehatan, pengetahuan terkait cara penanaman tanaman obat keluarga yang baik dan benar, serta kemampuan dalam mengolah tanaman obat keluarga dengan baik.
Kata Kunci: Kuliah Kerja Nyata, Pemberdayaan Masyarakat, Tanaman Obat Keluarga
The synthesis of novel lanthanum hydroxyborate at extreme conditions
Authors: Ibragimova Olga , Vaquero Lia , Hussein Zain , Drozd Vadym , Chariton Stella , Prakapenka Vitali , Chuvashova Irina 
Published: September 2023

The novel structure of lanthanum hydroxyborate La2B2O5(OH)2 was synthesized by the reaction of partially hydrolyzed lanthanum and boron oxide in a diamond anvil cell under high-pressure/high-temperature (HPHT) conditions of 30 GPa and ∼2,400 K. The single-crystal X-ray structure determination of the lanthanum hydroxyborate revealed: P3¯c1, a = 6.555(2) Å, c = 17.485(8) Å, Z = 6, R1 = 0.056. The three-dimensional structure consists of discrete planar BO3 groups and three crystallographically different La ions: one is surrounded by 9, one by 10, and one by 12 oxygen anions. The band gap was estimated using ab initio calculations to be 4.64 eV at ambient pressure and 5.26 eV at 30 GPa. The current work describes the novel HPHT lanthanum hydroxyborate with potential application as a deep-ultraviolet birefringent material.
Social interaction, support preferences, and the use of wearable health trackers
Authors: Pennington Natalie , Dam Linda 
Published: September 2023

IntroductionDrawing on uses and gratifications theory, social cognitive theory, and related work, this research assessed how social factors relate to reported weekly use and behavioral intentions toward the use of wearable health trackers (WHT).MethodsThrough two studies we surveyed current users of WHT, including smartwatches, to better understand what factors encouraged engagement. Study One (N = 333) consisted of a college student sample. Study Two (N = 319) was conducted through an online panel from Prolific.ResultsFor Study One, results suggested that connection, social comparison, and one's comfort with seeking support predicted weekly use, while need for support was a negative predictor of device use. In terms of behavioral intentions, connection and one's comfort with seeking support remained positive predictors. For Study Two, only one's comfort with seeking support predicted weekly use, while one's comfort with seeking support and social sharing both predicted behavioral intentions. Additional analysis in Study Two comparing users of dedicated WHT and smartwatches also found differences in terms of behavioral intentions and social sharing.DiscussionCollectively, the two studies offer insight into what social factors contribute to the use of WHT, including evidence that one's need for support for exercise may serve as a barrier to WHT use.
Prediction of formation pressure based on numerical simulation of in-situ stress field: a case study of the Longmaxi formation shale in the Nanchuan area, eastern Chongqing, China
Authors: Zhang Douzhong , Chen Kongquan , Tang Jiguang , Liu Ming , Zhang Peixian , He Guisong , Cai Jun , Tuo Xiusong 
Published: September 2023

The in-situ stress and formation pressure are important parameters in shale gas development. They directly affect the well wall stability, the direction of horizontal well drilling, and the fracturing effect during the shale gas development process. There are abundant shale gas resources in the southeastern Chongqing-Sichuan area, but the structure in the area is complex, and it is difficult to predict the in-situ stress and formation pressure. Therefore, in this paper, a finite element simulation model was established based on a large number of seismic, logging, and experimental rock mechanics data and the prediction accuracy of the stress field simulation was effectively improved. The construction of the stress field was based on the combined spring model, as well as the data related to the measured in-situ stress and the formation pressure obtained during drilling. The coupling relationship between the in-situ stress, the formation strain, and the formation pressure were derived to carry out the prediction of the distributions of the formation pressure and the formation pressure coefficient. The prediction results showed that the present-day maximum principal stress direction in the study area was about NE65°–110°, and the present-day maximum principal stress was 56.12–93.79 MPa. The present-day minimum principal stress direction was about NE335°–20°, and the present-day minimum principal stress was 48.06–71.67 MPa. The formation pressure was 2.8–88.25 MPa, and the formation pressure coefficient was 0.74–1.55. The formation pressure distribution was greatly affected by fault, tectonic location, in-situ stress and rock petrophysical properties, and the overpressure areas of the formation were distributed in the synclines and the deeply buried areas. This study shows that the finite element based formation pressure prediction method is effective.
Remnant cholesterol associates with hypertension beyond low-density lipoprotein cholesterol among the general US adult population
Authors: Shi Liu , Zhang Dongmei , Ju Jianqing , Wang Anlu , Du Tianyi , Chen Xuanye , Song Yewen , Gao Zhuye , Xu Hao 
Published: September 2023

BackgroundPrevious findings have indicated that elevated low-density lipoprotein cholesterol (LDL-C) and remnant cholesterol (RC) are associated with hypertension. We aim to explore whether higher RC levels may be associated with hypertension beyond LDL-C in the general US adult population.MethodsThis study included 10,842 adults from the National Health and Nutrition Examination Survey (NHANES) 1999–2018. Weighted multivariable logistic regression models were used to estimate the odds ratios (ORs) of hypertension for LDL-C and RC. We also performed analyses examining the association between hypertension and LDL-C vs. RC concordant/discordant groups.ResultsA total of 4,963 (41.54%, weighted) individuals had hypertension. The weighted median levels were LDL-C: 118mg/dL, RC: 20mg/dL. At lower LDL-C clinical cut-point, the proportion of discordantly high RC dramatically increased. After multivariable adjustment, log RC was associated with higher prevalence of hypertension [OR 2.54, 95% confidence interval (CI) 2.17–2.99]. Participants with the highest tertile of RC were more likely to have hypertension (OR 2.18; 95% CI 1.89-2.52) compared with those with the lowest tertile of RC. This association remained marked after including body mass index (BMI), LDL-C, high-density lipoprotein cholesterol (HDL-C) or triglycerides. The association between LDL-C and hypertension was absent after adjusting for BMI, RC or triglycerides. Compared with low LDL-C/low RC group, the discordant low LDL-C/high RC group was associated with hypertension (OR 2.04; 95% CI 1.72-2.42), whereas the high LDL-C/low RC group was not, regardless of BMI, HDL-C or triglycerides. Similar results were observed when examining discordance among different clinical cut-points, except for the cut-point of LDL-C 70 mg/dL and RC 13 mg/dL. To better understand the association, we performed an additional analysis, which showed that among participants with apolipoprotein B &lt; median (92mg/dL), those with discordant RC ≥ median (20mg/dL) had significantly higher odds of having hypertension (OR 1.73; 95% CI 1.38-2.17).ConclusionRC was associated with hypertension beyond LDL-C in the general US adult population. This association went beyond increased triglycerides levels, and lipoproteins other than apoB may be involved.
The causal relationship between gut microbiota and inflammatory dermatoses: a Mendelian randomization study
Authors: Mao Rui , Yu Qinyang , Li Ji 
Published: September 2023

BackgroundObservational studies have shown that gut microbiota is closely associated with inflammatory dermatoses such as psoriasis, rosacea, and atopic dermatitis (AD). However, the causal relationship between gut microbiota and inflammatory dermatosis remains unclear.MethodsBased on Maximum Likelihood (ML), MR-Egger regression, Inverse Variance Weighted (IVW), MR Pleiotropy RESidual Sum and Outlier (MR-PRESSO), Weighted Mode, and Weighted Median Estimator (WME) methods, we performed a bidirectional two-sample Mendelian randomization (MR) analysis to explore the causal relationship between gut microbiota and inflammatory dermatosis. The genome-wide association study (GWAS) summary data of gut microbiota came from the MiBioGen consortium, while the GWAS summary data of inflammatory dermatosis (including psoriasis, AD, rosacea, vitiligo, acne, and eczema) came from the FinnGen consortium and IEU Open GWAS project. Cochran’s IVW Q test tested the heterogeneity among instrumental variables (IVs). The horizontal pleiotropy was tested by MR-Egger regression intercept analysis and MR-PRESSO analysis.ResultsEventually, the results indicated that 5, 16, 17, 11, 15, and 12 gut microbiota had significant causal effects on psoriasis, rosacea, AD, vitiligo, acne, and eczema, respectively, including 42 protective and 34 risk causal relationships. Especially, Lactobacilli and Bifidobacteria at the Family and Genus Level, as common probiotics, were identified as protective factors for the corresponding inflammatory dermatoses. The results of reverse MR analysis suggested a bidirectional causal effect between AD and genus Eubacterium brachy group, vitiligo and genus Ruminococcaceae UCG004. The causal relationship between gut microbiota and psoriasis, rosacea, acne, and eczema is unidirectional. There was no significant heterogeneity among these IVs. In conclusion, this bidirectional two-sample MR study identified 76 causal relationships between the gut microbiome and six inflammatory dermatoses, which may be helpful for the clinical prevention and treatment of inflammatory dermatoses.
Heterogenous lung inflammation CT patterns distinguish pneumonia and immune checkpoint inhibitor pneumonitis and complement blood biomarkers in acute myeloid leukemia: proof of concept
Authors: Aminu Muhammad , Daver Naval , Godoy Myrna C. B. , Shroff Girish , Wu Carol , Torre-Sada Luis F. , Goizueta Alberto , Shannon Vickie R. , Faiz Saadia A. , Altan Mehmet , Garcia-Manero Guillermo , Kantarjian Hagop , Ravandi-Kashani Farhad , Kadia Tapan , Konopleva Marina , DiNardo Courtney , Pierce Sherry , Naing Aung , Kim Sang T. , Kontoyiannis Dimitrios P. , Khawaja Fareed , Chung Caroline , Wu Jia , Sheshadri Ajay 
Published: September 2023

BackgroundImmune checkpoint inhibitors (ICI) may cause pneumonitis, resulting in potentially fatal lung inflammation. However, distinguishing pneumonitis from pneumonia is time-consuming and challenging. To fill this gap, we build an image-based tool, and further evaluate it clinically alongside relevant blood biomarkers.Materials and methodsWe studied CT images from 97 patients with pneumonia and 29 patients with pneumonitis from acute myeloid leukemia treated with ICIs. We developed a CT-derived signature using a habitat imaging algorithm, whereby infected lungs are segregated into clusters (“habitats”). We validated the model and compared it with a clinical-blood model to determine whether imaging can add diagnostic value.ResultsHabitat imaging revealed intrinsic lung inflammation patterns by identifying 5 distinct subregions, correlating to lung parenchyma, consolidation, heterogenous ground-glass opacity (GGO), and GGO-consolidation transition. Consequently, our proposed habitat model (accuracy of 79%, sensitivity of 48%, and specificity of 88%) outperformed the clinical-blood model (accuracy of 68%, sensitivity of 14%, and specificity of 85%) for classifying pneumonia versus pneumonitis. Integrating imaging and blood achieved the optimal performance (accuracy of 81%, sensitivity of 52% and specificity of 90%). Using this imaging-blood composite model, the post-test probability for detecting pneumonitis increased from 23% to 61%, significantly (p = 1.5E − 9) higher than the clinical and blood model (post-test probability of 22%).ConclusionHabitat imaging represents a step forward in the image-based detection of pneumonia and pneumonitis, which can complement known blood biomarkers. Further work is needed to validate and fine tune this imaging-blood composite model and further improve its sensitivity to detect pneumonitis.
Demethylating agents in combination with CD7-targeted CAR-T for the successful treatment of a case with mixed-phenotype acute leukemia relapsed after allogeneic hematopoietic stem cell transplantation: A Case Report
Authors: Han Ying , Yao Hao , He Guang-cui , Lai Si-han , Deng Yan , Zhang Shan , He Ying , Xiong Yi-song , Chang Alex H. , Su Yi , Yi Hai 
Published: September 2023

BackgroundAllogeneic hematopoietic stem cell transplantation (allo-HSCT) has cured many patients with malignant hematologic diseases such as mixed phenotype acute leukemia (MPAL), while those relapsing after allo-HSCT still exhibit high mortality, poor prognosis, and no standard treatment modalities. It is necessary to explore more therapeutic modalities for patients with post-transplant relapse to obtain a better prognosis.Case presentationIn this case report, a young male with MPAL received allo-HSCT after reaching complete remission (CR) by induction chemotherapy. Unfortunately, relapse of both myeloid and T lineages occurred nine months later. After receiving demethylating chemotherapy, myeloid lineage measurable residual disease (MRD) turned negative. T-lineage MRD turned negative after CD7-targeted chimeric antigen receptor (CAR)-T cell therapy. The bone marrow remained MRD-negative for 4 months. This case preliminarily demonstrated a long-lasting CR with CD7-targeted CAR-T cell therapy, allowing a better prognosis.ConclusionDemethylating drugs combined with CD7-targeted CAR-T cell therapy is feasible in treating MPAL patients with relapse after transplantation, with good efficacy and safety, which will be a promising treatment option for MPAL.
Cytokine dysregulation despite immunoglobulin replacement therapy in common variable immunodeficiency (CVID)
Authors: Poto Remo , Pecoraro Antonio , Ferrara Anne Lise , Punziano Alessandra , Lagnese Gianluca , Messuri Carla , Loffredo Stefania , Spadaro Giuseppe , Varricchi Gilda 
Published: September 2023

IntroductionCommon variable immunodeficiency (CVID) is the most prevalent symptomatic primary immunodeficiency. CVID is a heterogeneous disorder with a presumed multifactorial etiology. Intravenous or subcutaneous immunoglobulin replacement therapy (IgRT) can prevent severe infections but not underlying immune dysregulation.MethodsIn this study, we evaluated the serum concentrations of proinflammatory (TNF-α, IL-1β, IL-6) and immunoregulatory cytokines (IL-10), as well as lipopolysaccharide (LPS) and soluble CD14 (sCD14) in CVID individuals with infectious only (INF-CVID), and those with additional systemic autoimmune and inflammatory disorders (NIC-CVID), and healthy donors (HD).ResultsOur results showed increased serum concentrations of TNF-α, IL-1β, IL-6, and IL-10 in both INF-CVID and NIC-CVID subjects compared to HD. However, elevations of TNF-α, IL-1β, IL-6, and IL-10 were significantly more marked in NIC-CVID than INF-CVID. Additionally, LPS concentrations were increased only in NIC-CVID but not in INF-CVID compared to HD. Circulating levels of sCD14 were significantly increased in NIC-CVID compared to both INF-CVID and HD.DiscussionThese findings indicate persistent cytokine dysregulation despite IgRT in individuals with CVID. Moreover, the circulating cytokine profile reveals the heterogeneity of immune dysregulation in different subgroups of CVID subjects.