bluuebunny/crossref_metadata_2025_split huggingface dataset:
Methods of Teaching Transgender Health in Undergraduate Nursing Programs
Authors: Lim Fidelindo , Eda Ozkara San 
Published: November 2023

Background:
Transgender populations experience disproportionately higher rates of mental and physical health issues such as suicidality and heart disease than their cisgender counterparts. Education of health professions students and providers is recognized as an effective method in mitigating transgender health disparities.

Purpose:
This narrative review investigated the methods in which transgender health is taught in undergraduate nursing programs. Suggestions for optimizing transgender health education are presented.

Method:
This review critically appraised and synthesized 28 articles that met these inclusion criteria: articles in English describing teaching strategies used in transgender health education with samples that include undergraduate nursing students.

Results:
Didactic lecture is the most widely used method, followed by role-play simulation, use of film and video, guest presentation, and high-fidelity and standardized patient simulation.

Conclusion:
Lectures remain the dominant method of delivering transgender health content. Improvements in students' knowledge and attitude related to transgender care were noted posteducation.
Short-Stay Left Colectomy for Colon Cancer: Is It Safe?
Authors: Papanikolaou Angelos , Chen Sophia Y , Radomski Shannon N , Stem Miloslawa , Brown Lawrence B , Obias Vincent J , Graham Ada E , Chung Haniee 
Published: November 2023

BACKGROUND:
Advances in surgical practices have decreased hospital length of stay (LOS) after surgery. This study aimed to determine the safety of short-stay (≤24-hour) left colectomy for colon cancer patients in the US.

STUDY DESIGN:
Adult colon cancer patients who underwent elective left colectomies were identified using the American College of Surgeons NSQIP database (2012 to 2021). Patients were categorized into 4 LOS groups: LOS 1 day or less (≤24-hour short stay), 2 to 4, 5 to 6, and 7 or more. Primary outcomes were 30-day postoperative overall and serious morbidity. Secondary outcomes were 30-day mortality and readmission. Multivariable logistic regression was performed to explore the association between LOS and overall and serious morbidity.

RESULTS:
A total of 15,745 patients who underwent left colectomies for colon cancer were identified with 294 (1.87%) patients undergoing short stay. Short-stay patients were generally younger and healthier with lower 30-day overall morbidity rates (LOS ≤1 day: 3.74%, 2 to 4: 7.38%, 5 to 6: 16.12%, and ≥7: 37.64%, p < 0.001). Compared with patients with LOS 2 to 4 days, no differences in mortality and readmission rates were observed. On adjusted analysis, there was no statistical difference in the odds of overall (LOS 2 to 4 days: odds ratio 1.90, 95% CI 1.01 to 3.60, p = 0.049) and serious morbidity (LOS 2 to 4 days: odds ratio 0.86, 95% CI 1.42 to 1.76, p = 0.672) between the short-stay and LOS 2 to 4 days groups.

CONCLUSIONS:
Although currently performed at low rates in the US, short-stay left colectomy is safe for a select group of patients. Attention to patient selection, refinement of clinical pathways, and close follow-up may enable short-stay colectomies to become a more feasible reality.
The Vacant Niche Revisited: Using Negative Results to Refine the Limits of Habitability
Authors: Ratliff L.E. , Fulford A.H. , Pozarycki C.I. , Wimp G. , Nichols F. , Osburn M.R. , Graham H.V. 
Published: November 2023

ABSTRACTTo define the boundaries of habitability, biologists often search for highly specialized organisms in extreme environments. However, negative life detections—when a method is unable to detect microorganisms in a given setting—are just as important to constrain the environmental limits of life on Earth. In turn, these limits inform the selection of targets for life detection on other worlds.We performed a comprehensive, though non-exhaustive, literature search for negative life detections in polyextreme environments. We then catalogued the physicochemical conditions at these sites to further understand the habitability limits for life on Earth and the effects of multiple stressors on habitability. Using multivariate statistical techniques, our study searched for combinations of environmental parameters where extremes support or inhibit life. Our search raised several methodological and analytical considerations relevant to life detection studies in extreme environments. Incomplete documentation of environmental factors and experimental protocol limitations in the extreme environment literature complicated our analyses. This demonstrates the need to report negative results, particularly in life detection experiments, and the potential value for standardized reporting protocols. Exploring the range of results possible from life-detection methodologies is key to constrain the limits of life on Earth and informs our search for life elsewhere.
NMR metabolomic modelling of age and lifespan: a multi-cohort analysis
Authors: Lau Chung-Ho E. , Manou Maria , Markozannes Georgios , Ala-Korpela Mika , Shlomo Yoav Ben- , Chaturvedi Nish , Engmann Jorgen , Gentry-Maharaj Aleksandra , Herzig Karl-Heinz , Hingorani Aroon , Järvelin Marjo-Riitta , Kähönen Mika , Kivimäki Mika , Lehtimäki Terho , Marttila Saara , Menon Usha , Munroe Patricia B. , Palaniswamy Saranya , Providencia Rui , Raitakari Olli , Schmidt Floriaan , Sebert Sylvain , Wong Andrew , Vineis Paolo , Tzoulaki Ioanna , Robinson Oliver 
Published: November 2023

AbstractMetabolomic age models have been proposed for the study of biological aging, however they have not been widely validated. We aimed to assess the performance of newly developed and existing nuclear magnetic resonance spectroscopy (NMR) metabolomic age models for prediction of chronological age (CA), mortality, and age-related disease.98 metabolic variables were measured in blood from nine UK and Finnish cohort studies (N ≈ 31,000 individuals, age range 24-86 years). We used non-linear and penalised regression to model CA and time to all-cause mortality. We examined associations of four new and two previously published metabolomic age models, with ageing risk factors and phenotypes. Within the UK Biobank (N≈ 102,000), we tested prediction of CA, incident disease (cardiovascular disease (CVD), type-2 diabetes mellitus, cancer, dementia, chronic obstructive pulmonary disease) and all-cause mortality.Cross-validated Pearson’srbetween metabolomic age models and CA ranged between 0.47–0.65 in the training set (mean absolute error: 8-9 years). Metabolomic age models, adjusted for CA, were associated with C-reactive protein, and inversely associated with glomerular filtration rate. Positively associated risk factors included obesity, diabetes, smoking, and physical inactivity. In UK Biobank, correlations of metabolomic age with chronological age were modest (r= 0.29–0.33), yet all metabolomic model scores predicted mortality (hazard ratios of 1.01 to 1.06 / metabolomic age year) and CVD, after adjustment for CA.While metabolomic age models were only moderately associated with CA in an independent population, they provided additional prediction of morbidity and mortality over CA itself, suggesting their wider applicability.
Development and utilization of new O2-independent bioreporters
Authors: Agranier Eva , Crétin Pauline , Joublin-Delavat Aurélie , Veillard Léa , Touahri Katia , Delavat François 
Published: November 2023

AbstractFluorescent proteins have revolutionized science since their discovery in 1962. They have enabled imaging experiments to decipher the function of proteins, cells and organisms, as well as gene regulation. GFP and all its derivatives are now standard tools in cell biology, immunology, molecular biology and microbiology laboratories around the world. A common feature of these proteins is their O2-dependent maturation allowing fluorescence, which precludes their use in anoxic contexts. In this work, we report the development andin cellulocharacterization of genetic circuits encoding the O2-independent KOFP-7 protein, a flavin-binding fluorescent protein. We have optimized the genetic circuit for high bacterial fluorescence at population and single-cell level, implemented this circuit in various plasmids differing in host range, and quantified their fluorescence under both aerobic and anaerobic conditions. Finally, we showed that KOFP-7 based constructions can be used to produce fluorescing cells ofV. diazotrophicus, a facultative anaerobe, demonstrating the usefulness of the genetic circuits for various anaerobic bacteria. These genetic circuits can thus be modified at will, both to solve basic and applied research questions, opening a highway to shed light on the obscure anaerobic world.ImportanceFluorescent proteins are used since decades, and have allowed major discoveries in biology in a wide variety of fields, and are used in environmental as well as clinical contexts. GFP and all its derivatives share a common feature: they rely on the presence of O2for protein maturation and fluorescence. This dependency precludes their use in anoxic environments. Here, we constructed a series of genetic circuits allowing production of KOFP-7, an O2-independant Flavin-Binding Fluorescent Protein. We demonstrated thatEscherichia colicells producing KOFP-7 are fluorescent, both at the population and single-cell levels. Importantly, we showed that, unlike cells producing GFP, cells producing KOFP-7 are fluorescent in anoxia. Finally, we demonstrated thatVibrio diazotrophicusNS1, a facultative anaerobe, is fluorescent in the absence of O2when KOFP-7 is produced.Altogether, the development of new genetic circuits allowing O2-independent fluorescence will open new perspective to study anaerobic processes.
Mobile tuberigen impacts tuber onset synchronization and canopy senescence timing in potato
Authors: van den Herik Bas , Bergonzi Sara , Bachem Christian W.B. , ten Tusscher Kirsten H. 
Published: November 2023

AbstractYield of harvestable organs is a complex function of photosynthetic output, and sink-strength and timing of competing carbon sinks. In potato (Solanum tuberosum) the effect of tuber onset timing and post-tuberization canopy senescence on growth dynamics and tuber fresh weight are poorly understood. To advance our understanding we compared above- and belowground traits of wildtype plants (WT) withStSP6A, i.e., tuberigen, knockdown plants (SP6Ai) and developed simple computational models to aid interpretation of results. We find that SP6Ai results in a delay of approximately 2 weeks in tuber onset, yet has a 4-to-5-week delayed canopy senescence. Together this results in a prolonged tuber growth phase, with reduced synchronization in tuber onset and a resulting increased variance in tuber sizes, while overall final tuber fresh weight remains similar. Using a leaf and tuber growth model comparing various leaf senescence mechanisms, we find that resource competition, and not a shared signal for tuberization and senescence, is able to explain how delayed tuberization leads to further delayed senescence. Our results point to a role for resource competition in the correlated timing of tuber onset and canopy senescence, as well as a leading role forStSP6Ain tuber onset synchronization and tuber size uniformity.Graphical Abstract
Sustainability reporting, board diversity, earnings management and financial statements readability: evidence from an emerging economy
Authors: Ndegwa James Ndirangu 
Published: November 2023

Purpose
This paper aims to investigate the moderating effect of sustainability reporting on the relationship between the independent variables of board diversity, and earnings management and the dependent variable of readability of financial statements.

Design/methodology/approach
The study panel data regression analysis involved 36 Kenyan-listed companies from 2016 to 2020.

Findings
Key findings were that increased board diversity was found to significantly improve the readability of financial statements. Discretionary earnings management was found to significantly reduce the readability of financial statements. Sustainability reporting was found to significantly increase the readability of financial statements, and it moderated the relationship between board diversity, earnings management and financial statements readability in Kenya.

Research limitations/implications
The study sample of 36 non-financial listed in the Nairobi Securities Exchange was very small and was affected by the problem of thin trading; hence, caution should be adopted when interpreting the findings.

Practical implications
The Capital Markets Authorities (CMA) as a policymaker should enforce sustainability reporting by Kenyan listed firms as there is evidence that the reporting enhances the readability of financial statements. The Institute of Certified Public Accountants as a policymaker should closely monitor the published financial statements of firms for earnings management and punish the perpetrators, as there is empirical evidence that the practice reduces the readability of financial statements.

Social implications
Sustainability reporting is successful as a moderating variable between readability of financial statements and determinants of readability of financial statements.

Originality/value
This study contributes to knowledge by studying sustainability reporting as a moderating variable between the independent variables of board diversity and earnings management and the dependent variable of readability of financial statements and measured sustainability reporting using a dummy variable for the period before and after the enactment and release of CMA code of 2016 on corporate governance that required sustainability reporting by Kenyan listed companies.
How the little tough man ruled the giants in the Turkish Basketball League
Authors: Unsal Efe 
Published: November 2023

Learning outcomes
After reading and analysing the case study, the students would be able to distinguish the leadership styles based on leaders’ traits and behaviours, argue the importance of trust in leader–follower relationships thanks to the real-life examples presented and defend their side on the debate of whether leadership is born or made with the related theories and examples.

Case overview/synopsis
The teams coached by the successful Turkish basketball coach, Çetin Yılmaz, had reached the finals of the Turkish Basketball League six times and became champions three times. He assumed the coaching position of the Tuborg basketball team in December 2005. Although Tuborg’s Turkey branch made a serious financial investment in basketball, they were at the bottom of the league in the middle of the season. When Yılmaz took over the coaching position, the Tuborg basketball team’s main objective was not to be relegated from the top league in the 2005–2006 season. The team, working very hard, overcame the fear of relegation in two months but still had a very symbolic goal in front of it: winning the most prestigious game of the season by defeating the Karşıyaka team. However, in the last minutes of the game, with the influence of passionate Karşıkaya fans, the Tuborg team got scared and lost the game. At the end of the match, the club president entered the locker room and started shouting at the players, forcing the coach to face a severe dilemma. Either he would remain silent and risk damaging his leading position in the eyes of the players, or he would risk being fired by going against the president, even though he thought the president was right in what he said.

Complexity academic level
The target audience of this case study is undergraduate students. The field of study is sports management, leadership and coaching. This case study can be used in management, organizational behaviour and sports management courses while covering leadership and coaching topics.

Supplementary materials
Teaching notes are available for educators only.

Subject code
CSS 6: Human resource management.
Transformation of the architect's role: a reading of architectural education in Turkey through the Mimarlık journal (1963–2000)
Authors: Özer Özgür Gi̇zem , Şenel Aslıhan 
Published: November 2023

PurposeThis study investigates the transformation of the architect's role as portrayed in written texts by analyzing discursive practices concerning architectural education in Turkey between 1963 and 2000.Design/methodology/approachThe research employs critical discourse analysis (CDA) to examine selected texts published in the Mimarlık journal, representing the Chamber of Architects of Turkey. By embracing M. Bakhtin's “dialogism” approach, it aspires to foster new discussions on architectural education and establishes a “dialogical landscape” showcasing various voices and arguments. The research supplements its methodology by mapping the dialogical landscape, illustrating the relationality of discursive practices.FindingsThe paper contends that alterations in the missions, goals, and priorities of the architectural discipline significantly impact architectural education. Rather than focusing on individual perspectives, the creation of new dialogical platforms, emphasizing the interplay of diverse and conflicting viewpoints, offers more comprehensive pathways to guide the future of architectural education.Originality/valueDebates and conflicts regarding the architect's role are central to architectural education. This article offers a novel perspective on the history of architectural education in Turkey by analyzing shifts in the definition and role of the architect as expressed in the Mimarlık journal. By integrating the principles of dialogism into the study of educational discourses and revealing the relationality between material-discursive practices, it aims to enrich the discourse and contribute value to critical studies on architectural education.
Frequent supply chain disruptions and firm performance: the moderating role of exploitation, exploration and supply chain ambidexterity
Authors: Ambulkar Saurabh , Ralston Peter M. , Polyviou Mikaella , Sanders Nada 
Published: November 2023

PurposeThe present manuscript assesses how firms should manage frequent supply chain disruption triggers and whether these firms should use existing supply chain competencies, develop new ones or both to mitigate any adverse consequences on financial performance.Design/methodology/approachData for the study come from a survey administered to professionals in India. India was an appropriate base for the study because of its developing economy and businesses often facing SC disruptions in the marketplace.FindingsThe findings show that the negative association between the frequency of supply chain disruption triggers and financial performance is weaker when a firm utilizes supply chain exploitation competencies. Conversely, the negative association between the frequency of supply chain disruption triggers and financial performance becomes stronger when using supply chain exploration competencies. Most significantly, however, the authors show that a strategy of supply chain ambidexterity – one that combines both exploitation and exploration practices – is more beneficial in mitigating the impact of frequent disruption triggers on firm financial performance compared to the other strategies.Originality/valueThese findings contribute to the literature, extending the benefits of ambidexterity beyond domains of innovation, manufacturing flexibility, competitiveness and firm performance to include mitigation of supply chain disruptions.
Police service in urban destination points: does it promote urban destination advocacy among tourists?
Authors: Singh Rashmi , Jena Lalatendu Kesari 
Published: November 2023

Purpose
This study aims to test an integrated model that examines the relationship between the service qualities of police at any urban tourist destination and the tourist urban destination advocacy at tourist cities in the Shimla region of India, where tourists’ trust in police acts as a mediating variable. This study mainly focused on the type of service shown by police officials to develop trust among the tourists, resulting in their urban destination advocacy.

Design/methodology/approach
The questionnaire was adopted from previously developed and validated scales. The questionnaire was administered to different tourists who came to India. This study used the bootstrapping technique and structural equation modelling (SEM) to address the research questions and test the hypotheses.

Findings
This study results indicate that trust in the police mediates the relationship between police service quality and tourist satisfaction at any urban tourist destination. The study’s findings add to the literature on tourists’ trust in policing tourist sites, police service quality and leader behaviour.

Research limitations/implications
The above-tested model has a very limited number of constructs. There are a variety of additional antecedents (e.g. police organization culture and urban destination attributes) and consequences (word-of-mouth referrals and customer identification) that could be considered for future research to develop a more comprehensive model. The cross-sectional study raises concerns about the causal relationships between constructs in the tested model. More substantial evidence of causality via longitudinal and experimental studies is needed.

Originality/value
The study’s findings added a chapter to the literature by identifying how police service quality impacts tourist trust building and urban destination advocacy.
Understanding sustainable service ecosystems: a meso-level perspective
Authors: Palakshappa Nitha , Dodds Sarah , Stangl Loren M. 
Published: November 2023

Purpose
The world continues to grapple with grand challenges – climate change, pandemic, poverty, social injustice and diminishing resources – requiring mitigation if we are to focus on well-being and move towards a more sustainable future. Cultivating sustainable ecosystems offers a possible solution. The purpose of this paper is to understand how sustainable organizations at the meso level can nurture sustainable service ecosystems that provide the potential for greater well-being outcomes for individuals, business, society and the planet.

Design/methodology/approach
Case study data is gathered from 11 sustainable fashion organizations operating at the meso level within a complex ecosystem. The analysis includes interviews with founders and/or key managers and secondary information from company websites and publicly available reports.

Findings
The findings identify key value co-creation sustainable practices at the meso level that facilitate the function of the service ecosystem to create well-being outcomes. Value co-creation practices include – embedding a sustainable ethos; implementing sustainable strategies that embrace innovation, transparency and stakeholder collaboration; and incorporating sustainable communication practices that engage.

Originality/value
Encapsulating sustainability within macromarketing and service ecosystems enables the development of a sustainable service ecosystems framework that has the potential to offer enhanced well-being. Implications for marketing practice in terms of important factors that facilitate service-sustainable ecosystems to enhance well-being are considered.