bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Force‐Assisted Li−O2 Battery Based on Piezoelectric Catalysis and Band Bending of MoS2/Pd Cathode
Authors: Tian Song‐Lin , Song Li‐Na , Chang Li‐Min , Liu Wan‐Qiang , Wang Huan‐Feng , Xu Ji‐Jing 
Published: December 2023

AbstractThe high overpotential caused by the slow kinetics of oxygen reduction (ORR) and oxygen evolution (OER) has greatly limited the practical application of lithium‐oxygen (Li−O2) batteries. The adoption of force‐field‐assisted system based on a newly developed piezocatalysis is promising in reducing the overpotential. Herein, a force‐assisted Li−O2 battery is first established by employing MoS2/Pd nanocomposite cathode, in which the piezoelectric polarization as well as built‐in electric field are formed in MoS2 piezoelectric catalyst under ultrasound activation, leading to the continuously separated electrons and holes to enhance the ORR and OER kinetics. Moreover, the introduction of Pd can promote the electrons transfer and further inhibit the complexation of electron–hole pairs, contributing to enhanced catalytic activity in the decomposition/generation of discharge products, resulting in reduced discharge/charge overpotentials. Thus, the force‐assisted MoS2/Pd‐based Li−O2 battery is capable of adjusting the output and input energies by the assisted ultrasonic wave. An ultra‐low charging platform of 2.86 V and a high discharging platform of 2.77 V are achieved. The proposed unique force‐assisted strategy can also be applied to lithium carbon dioxide battery system through the effective reduction and separation of CO2 and CO32−, providing significant insights in achieving efficient energy conversion for metal−air batteries.
Corrosion Resistant Multilayered Electrode Comprising Ni3N Nanoarray Overcoated with NiFe‐Phytate Complex for Boosted Oxygen Evolution in Seawater Electrolysis
Authors: Li Ping , Zhao Shien , Huang Yuqi , Huang Quhua , Xi Baojuan , An Xuguang , Xiong Shenglin 
Published: December 2023

AbstractEngineering high‐performance oxygen evolution reaction (OER) anode material with high activity, selectivity, and strong robustness against chloride corrosion is critical to advance seawater electrolysis for large‐scale production of H2, yet a daunting challenge. Herein it is reported for the first time, the engineer of a multilayered electrode consisting of Ni foam‐supported Ni3N porous nanosheet array decorated with NiFe‐phytate coordination complex overlayer (NF/Ni3N@NiFe‐PA) via a facile interfacial coordination assembly, for remarkably boosted and sustained OER in alkaline seawater electrolysis. Benefitting from regulated electronic state by synergism between Ni and Fe species, boosted proton‐coupled electron transfer via accelerating proton movement with the aid of incorporated phytic acid as proton transfer relay, and promoted mass transfer rendered by unique superhydrophilic and superaerophobic property, the resulting NF/Ni3N@NiFe‐PA demonstrates prominent OER activity in seawater. Impressively, integrating anticorrosive Ni3N with NiFe‐PA complex and in situ generated NiFeOOH can collaboratively contribute to chloride repelling, leading to exceptional corrosion resistance of the electrode. This work affords a novel paradigm to engineer active and corrosion‐resistive anode for selective OER in saline water electrolysis via simultaneous geometric and electronic structural manipulation.
Friedel–Crafts Acylation for Accessing Multi‐Bridge‐Functionalized Large Pillar[n]arenes
Authors: Shi Tan‐Hao , Akine Shigehisa , Ohtani Shunsuke , Kato Kenichi , Ogoshi Tomoki 
Published: December 2023

AbstractPillar[n]arenes can be constructed using a Friedel–Crafts alkylation process. However, due to the reversible nature of the alkylation, mixture of large pillar[n]arenes (n≥7) are obtained as minor products, and thus laborious purification are necessary to isolate the larger pillar[n]arenes. Moreover, inert methylene bridges are introduced during the alkylation process, and the multi‐functionalization of the bridges has never been investigated. Herein, an irreversible Friedel–Crafts acylation is used to prepare pillar[n]arenes. Due to the irreversible nature of the acylation, the reaction of precursors bearing carboxylic acids and electron‐rich arene rings results in a size‐exclusive formation of pillar[n]arenes, in which the ring‐size is determined by the precursor length. Because of this size‐selective formation, laborious separation of undesired macrocycles is not necessary. Moreover, the bridges of pillar[n]arenes are selectively installed with reactive carbonyl groups using the acylation method, whose positions are determined by the precursor used. The carbonyl bridges can be easily converted into versatile functional groups, leading to various laterally modified pillar[n]arenes, which cannot be accessed by the alkylation strategy.
Polyamide film containing a molecularly imprinted polymer prepared on a paper surface by interfacial polymerization and its selective adsorption of benzalkonium chloride
Authors: Ichiura Hideaki , Kawahara Yu 
Published: December 2023

AbstractIn this study, paper coated with a polyamide film containing a molecularly imprinted polymer (MIP) of benzalkonium chloride (BKC) is prepared. Its BKC adsorption ability and selectivity for BKC adsorption are investigated. The MIP is prepared by agitating an ethylenediamine solution containing an azo initiator, BKC as a template material, and methacrylic acid (MAA) as the functional monomer. First, filter paper soaked in this mixture is impregnated with a cyclohexane solution of terephthaloyl chloride and a BKC–MAA–MIP‐containing polyamide film is prepared on the surface of the paper. Paper containing BKC–MAA–MIP adsorbs BKC. The paper with the highest BKC removal efficiency is prepared under the following conditions: 4 mL MAA functional monomer, 2.5 w/v% ethylenediamine, and 10 min MIP synthesis time. The paper with BKC–MAA–MIP selectively adsorbs BKC from a solution containing BKC, tetracycline hydrochloride, and caffeine. Thus, a polyamide film containing BKC‐MAA‐MIP formed on paper can effectively and selectively remove BKC from aqueous environments.
Effect of Anti‐S100A4 Monoclonal Antibody Treatment on Experimental Skin Fibrosis and Systemic Sclerosis–Specific Transcriptional Signatures in Human Skin
Authors: Trinh‐Minh Thuong , Györfi Andrea‐Hermina , Tomcik Michal , Tran‐Manh Cuong , Zhou Xiang , Dickel Nicholas , Tümerdem Bilgesu Safak , Kreuter Alexander , Burmann Sven‐Niklas , Borchert Signe Vedel , Hussain Rizwan Iqbal , Hallén Jonas , Klingelhöfer Jörg , Kunz Meik , Distler Jörg H. W. 
Published: December 2023

ObjectiveS100A4 is a DAMP protein. S100A4 is overexpressed in patients with systemic sclerosis (SSc), and levels correlate with organ involvement and disease activity. S100A4−/− mice are protected from fibrosis. The aim of this study was to assess the antifibrotic effects of anti‐S100A4 monoclonal antibody (mAb) in murine models of SSc and in precision cut skin slices of patients with SSc.MethodsThe effects of anti‐S100A4 mAbs were evaluated in a bleomycin‐induced skin fibrosis model and in Tsk‐1 mice with a therapeutic dosing regimen. In addition, the effects of anti‐S100A4 mAbs on precision cut SSc skin slices were analyzed by RNA sequencing.ResultsInhibition of S100A4 was effective in the treatment of pre‐established bleomycin‐induced skin fibrosis and in regression of pre‐established fibrosis with reduced dermal thickening, myofibroblast counts, and collagen accumulation. Transcriptional profiling demonstrated targeting of multiple profibrotic and proinflammatory processes relevant to the pathogenesis of SSc on targeted S100A4 inhibition in a bleomycin‐induced skin fibrosis model. Moreover, targeted S100A4 inhibition also modulated inflammation‐ and fibrosis‐relevant gene sets in precision cut SSc skin slices in an ex vivo trial approach. Selected downstream targets of S100A4, such as AMP‐activated protein kinase, calsequestrin‐1, and phosphorylated STAT3, were validated on the protein level, and STAT3 inhibition was shown to prevent the profibrotic effects of S100A4 on fibroblasts in human skin.ConclusionInhibition of S100A4 confers dual targeting of inflammatory and fibrotic pathways in complementary mouse models of fibrosis and in SSc skin. These effects support the further development of anti‐S100A4 mAbs as disease‐modifying targeted therapies for SSc.
Graduate anatomy education: How are we training the future generations of anatomy educators?
Authors: Hall Tyler R. , Mosley Claudia F. , Balta Joy Y. 
Published: December 2023

AbstractThe teaching of anatomy is relevant to many fields and anatomy teachers are in demand. Individuals with a graduate anatomy education are some of the most sought‐after candidates to fill open teaching positions, but it is unclear as to what constitutes a graduate anatomy education. The purpose of this study was to investigate the components of a graduate anatomy education in the United States. A survey regarding the components of doctoral, master's, and graduate certificate programs was distributed to program directors and department chairs at 71 US institutions. Respondents indicated that there were 17 doctoral, 28 master's, and 9 graduate certificate programs. Students completed coursework in all the traditional anatomical subdisciplines in approximately half of doctoral (53%) and master's (57%) programs, though the number was lower in graduate certificate programs (22%). In comparison, within 12 programs (5 doctoral, 4 master's, and 3 graduate certificate) students were required to complete coursework in less than 2 anatomical subdisciplines. Required coursework outside the subdisciplines usually involved educational theories and practices (61% of programs), research methods (52% of programs), and/or physiology (37% of programs). Respondents indicated that most programs (81%) were designed to prepare their students to teach. It appears that graduate anatomy training likely involves gross anatomy coursework, coursework in another anatomical subdiscipline, and coursework in educational theories and practices. Given the likely decline in the number of doctoral‐level anatomy programs from 21 to 19, serious consideration should be given to hiring teaching candidates with master's or graduate certificate training in anatomy.
Creating evidence‐based engaging online learning resources in neuroanatomy
Authors: Booker James , Woodward Charlotte , Taylor Charles , Robson Alistair , Border Scott 
Published: December 2023

AbstractOnline anatomical resources are rising in popularity since the COVID‐19 pandemic, but the pedagogical principles and effectiveness of their use remain unclear. This article aims to demonstrate evidence‐informed ways in which fellow educators can create engaging online learning resources in clinical neuroanatomy and compare the effectiveness of text‐based and online learning resources. Data were analyzed from the Soton Brain Hub (SBH) YouTube page. Separately, a cross‐sectional study comparing the learning gain of using text‐based and video resources was done. The knowledge gain and retention were compared between groups using a pre‐teaching and post‐teaching multiple choice questions. YouTube analytics showed the average time a viewer spends on a video was found to be highly correlated to the length of the video, r = 0.77, p < 0.001 (0.69–0.82). The cross‐sectional study indicated a significant difference in mean normalized learning gain of video resources 61.9% (n = 53, CI 56.0–67.7%) versus text resources 49.6% (n = 23, CI 39.1–60.1%) (p = 0.030). However, there was no difference in retained learning gain between video resources 39.1% (n = 29, CI 29.2–49.0%) versus text‐based 40.0% (n = 13, CI 23.9–56.1%) (p = 0.919). Students engage most with short videos less than 5 min which reduces the intrinsic load of learning. Online resources are as effective as text‐based resources in providing learning gain and retention. In the future, the continued rise in popularity of online learning resources may result in further reduction in traditional face‐to‐face teaching.
Exploring the mediating effect of camouflaging and the moderating effect of autistic identity on the relationship between autistic traits and mental wellbeing
Authors: Moore Heather L. , Cassidy Sarah , Rodgers Jacqui 
Published: December 2023

AbstractMental health difficulties are prevalent among autistic adults. Camouflaging (behaving differently to fit in) may be a mechanism by which autistic traits and mental health difficulties relate to each other, but little research has considered the role of different facets of camouflaging. Additionally, autistic identity might buffer against camouflaging and mental health difficulties. This research aims to explore the mediating effects of camouflaging behaviours on the relationship between autistic traits and both positive and negative mental wellbeing, as well as how autistic identity might moderate the relationship between autistic traits and camouflaging, and also mental health. Data were available for 627 autistic adults, recruited through volunteer databases and social media. Participants completed measures of autistic traits, anxiety, depression, positive wellbeing, camouflaging behaviours (compensating for difficulties, masking, and assimilating/putting on an act) and autistic identity. Mediation and moderated mediation models were tested, applying 95% bootstrapped CIs (10,000 resamples) and including age, gender and diagnosis as covariates. There were no significant direct effects between autistic traits and mental wellbeing. Assimilation was a significant mediator of all mental wellbeing measures, and compensation was a significant mediator of positive wellbeing only. Autistic identity was not a significant moderator. Assimilation and compensation should be considered when offering psychological interventions to support mental wellbeing of autistic people. Additional research into external drivers of camouflaging (e.g. stigma) and mechanisms by which camouflaging impacts mental wellbeing, such as autonomy, authenticity, skill mastery and community, may identify other areas of support. Concurrently, societal change is necessary to reduce the need to camouflage.
A Facile Preparation of N‐Heterocyclic Olefins: Ring‐Opening Polymerization of β‐Butyrolactone and Frustrated Lewis Pair Reactivity**
Authors: Rajendran Natesan Mannangatti , Lu Qi , Bouffard Jean 
Published: December 2023

AbstractA direct synthesis of N‐heterocyclic olefins (NHOs) and their mesoionic congeners (mNHOs) from N‐heterocyclic carbenes and N‐aziridinylimines is reported. The reaction provided diverse functionalized (m)NHOs and π‐extended analogues. The prepared NHOs initiated the ring‐opening polymerization of β‐butyrolactone, and insertion of aldehyde and nitrile into an NHO‐B(C6F5)3 adduct was demonstrated.
Carbonylation as a Key Step in New Tandem Reactions – A Route to BODIPYs
Authors: Miller Lukas , Impelmann Alba , Bauer Felix , Breit Bernhard 
Published: December 2023

AbstractHerein, a highly efficient five‐step reaction sequence to BODIPYs is presented. The key step is the combination of transition metal‐catalyzed in‐situ generation of aldehydes and their subsequent organocatalytic activation to yield dipyrromethanes, which are further converted to the corresponding BODIPY. Classic syntheses towards BODIPYs have relied on aldehydes or acid chlorides, which are often not commercially available and rather sensitive to handle. The presented approach starts from readily available and stable alkenes or aryl‐bromides, which allows to extend the range of readily available BODIPYs that can be tailored for their specific use. The synthesis of 55 derivatives with overall yields of up to 78 % demonstrates the wide applicability and advantages of the presented method.
Acceptability of psilocybin‐assisted group therapy in patients with cancer and major depressive disorder: Qualitative analysis
Authors: Beaussant Yvan , Tarbi Elise , Nigam Kabir , Miner Skye , Sager Zachary , Sanders Justin J. , Ljuslin Michael , Guérin Benjamin , Thambi Paul , Tulsky James A. , Agrawal Manish 
Published: December 2023

AbstractBackgroundThe present study explored the acceptability of psilocybin‐assisted group therapy from the perspective of patients with cancer and depression who participated in a clinical trial assessing the safety and efficacy of this novel intervention.MethodsGuided by the conceptual framework of acceptability, the authors conducted semi‐structured interviews with participants of the psilocybin trial. Data were analyzed using template and thematic analyses.ResultsParticipants’ (n = 28) perspectives on the acceptability of the group and simultaneous sessions was generally positive, both in terms of safety and efficacy: first, the groups contributed to increase participants’ sense of safety and preparedness as they were engaging in the therapy; and second, the groups fostered a sense of connection and of belonging, which served to enrich and deepen the meaning of participants’ experience, ultimately opening a dimension of self‐transcendence and compassion. Other subthemes related to factors influencing the acceptability of the group approach included: 1) the importance of the therapeutic framework, 2) the complementary value of individual sessions, 3) disruptive factors related to the group and/or simultaneous setting, and 4) opportunities and challenges related to group size and how to structure interactions.ConclusionsThis study enhances understanding of what promotes acceptability of the psilocybin‐assisted therapy group model for the treatment of MDD in cancer patients.Plain Language Summary

We conducted exit interviews with participants of a phase 2 trial of psilocybin‐assisted therapy (PAT) conducted in a community cancer center, to assess the acceptability of a novel psilocybin delivery model combining simultaneous individual therapy and group sessions.
Our findings support the acceptability of this intervention and suggest that in addition to being feasible, it might also enhance participants’ perceived safety and efficacy compared to uniquely individual or group delivery models of PAT.
Our analysis highlights critical factors conditioning acceptability and suggests new ways PAT may be scaled and integrated into cancer care.
A Facile Synthetic Approach for TiO2@NiO Core‐shell Nanoparticles using TiO2@Ni(OH)2 Precursors and their Photocatalytic Application
Authors: Rana Pankaj , Jeevanandam Pethaiyan 
Published: December 2023

AbstractThe current study presents a simple and an efficient chemical method for the synthesis of TiO2@NiO core‐shell nanoparticles (CSNPs) as photocatalyst for effective degradation of rhodamine B (RhB) in an aqueous solution upon sunlight irradiation. First, TiO2 spheres were synthesized using a wet chemical method. Then, TiO2@Ni(OH)2 precursors were prepared via homogeneous precipitation and TiO2@NiO core‐shell nanoparticles were obtained on calcination of the precursors. The synthesized precursors and the TiO2@NiO CSNPs were analyzed using XRD, FT‐IR, FESEM and DRS. XRD data shows the presence of both TiO2 and NiO phases in the TiO2@NiO samples. FE‐SEM and TEM analyses confirm coating of NiO NPs on TiO2 spheres with varying shell thickness (40 nm to 170 nm). Optical studies reveal that TiO2@NiO CSNPs possess band gap of about 3.7 eV. Photoluminescence (PL) results show lower recombination rate of e− and h+ pairs in the TiO2@NiO CSNPs. XPS studies confirm the presence of different elements in the TiO2@NiO CSNPs. Magnetic investigations reveal ferromagnetic behavior of the core‐shell NPs at 5 K. The TiO2@NiO CSNPs were explored as photocatalyst for the degradation of rhodamine B in water under natural sunlight. The TiO2@NiO CSNPs exhibit better photocatalytic activity compared to TiO2 and NiO nanoparticles.
Rare‐earth Element‐based Electrocatalysts Designed for CO2 Electro‐reduction
Authors: Wang Hengan , Kang Xinchen , Han Buxing 
Published: December 2023

AbstractElectrochemical CO2 reduction presents a promising approach for synthesizing fuels and chemical feedstocks using renewable energy sources. Although significant advancements have been made in the design of catalysts for CO2 reduction reaction (CO2RR) in recent years, the linear scaling relationship of key intermediates, selectivity, stability, and economical efficiency are still required to be improved. Rare earth (RE) elements, recognized as pivotal components in various industrial applications, have been widely used in catalysis due to their unique properties such as redox characteristics, orbital structure, oxygen affinity, large ion radius, and electronic configuration. Furthermore, RE elements could effectively modulate the adsorption strength of intermediates and provide abundant metal active sites for CO2RR. Despite their potential, there is still a shortage of comprehensive and systematic analysis of RE elements employed in the design of electrocatalysts of CO2RR. Therefore, the current approaches for the design of RE element‐based electrocatalysts and their applications in CO2RR are thoroughly summarized in this review. The review starts by outlining the characteristics of CO2RR and RE elements, followed by a summary of design strategies and synthetic methods for RE element‐based electrocatalysts. Finally, an overview of current limitations in research and an outline of the prospects for future investigations are proposed.
Participatory curriculum development: The case of EUTOPIA, a European university alliance
Authors: Moriau Linde , Angouri Jo 
Published: December 2023

AbstractThis paper reports on a model for participatory curriculum development that builds on a ‘connected learning communities’ (CLC) approach. We describe and analyse the trajectory of six CLC‐cases using a framework informed by Social Practice Theory (SPT). The activities we report on took place during the first pilot year (2020–2021) of a transnational University Alliance involving six European universities. Data were drawn from document analysis, direct observations and ongoing dialogue with students and staff involved in the CLCs. Our findings illustrate the affordances of building on existing practice for curriculum development in international contexts and point out the importance of well‐equipped collaborative environments that encourage critical analysis and active experimentation. We found that the CLC model and SPT framework are helpful contributions in the field of curriculum development and argue that connected curriculum‐making approaches help shape versatile environments that can effectively transform and enhance educational provisions, experiences and outcomes.