bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of implementing the Public Entities Corporate Governance Act (PECG Act) Chapter 10:31 by State Owned Enterprises (SOEs) in Zimbabwe.
Authors: Mthombeni Admire , Obert Sifile , Rangarirai Mbizi , Masenya Malesela 
Published: October 2023

The study sought to determine the impact of the Public Entities Corporate Governance Act Chapter 10:31(PECG Act ). The Act is the main piece of legislation governing corporate governance practices for State Owned Enterprises in Zimbabwe. In this view, the study adopted a mixed-methods approach in which pragmatism philosophy was applied. A convergent parallel design was used in which data was gathered using a structured questionnaire and an interview guide. The target population consisted of top and middle management, board members, board chairpersons, and CEOs of SOEs found in Zimbabwe. Using the sampling procedure developed by Krejcie and Morgan (1970), a sample size of 351 individuals was determined for quantitative data, and sixteen (16) interviews were done until saturation was reached. The research employed stratified random sampling for sampling respondents for quantitative data and purposive sampling was used for sampling respondents for qualitative data. SPSS version 23 was used to analyse quantitative data, whilst NVivo version 12 was used to analyse qualitative data. The main impact of the PECG Act was that it fosters accountability, transparency, and responsibility and encourages strategic planning for SOEs. The research also confirmed that reforms on restrictions on the remuneration of board members(RRORB) have a positive effect on corporate governance practices in SOEs, and reforms on dismissal and resignation (RDRBM) of board members lead to best corporate governance in SOEs. The study recommended that responsible authorities should make strict enforcement to comply with the dictates of the PECG Act. The study had a limitation that results from broad SOE categories may not be generalised to specific SOE categories.
Embodying the Audiovisual Scene
Authors: Coëgnarts Maarten 
Published: October 2023

Abstract
This article provides an embodied cognitive account of sound in film. Treating sound and image as equal partners, we first develop a spatial model for film sound that is based on the inferential logic of the container image schema; an embodied schema which has been argued to play a pivotal role in human reasoning. Next, we use this model to distinguish between three kinds of dynamic sound patterns of containment in film: (1) sound vectors that cross the on-screen/off-screen border within diegetic space, (2) sound vectors that shift from one diegetic time and/or space into another, and (3) sound vectors that cross the diegetic/non-diegetic border. The theoretical entailments of these patterns for film sound analysis will be illustrated through various case examples of narrative cinema.
Book Reviews
Authors: Bálint Katalin E. , Brown William , Schlickers Sabine , Sheehan Rebecca A. 
Published: October 2023

James Cutting. Movies on Our Mind. Oxford: Oxford University Press, 2021, 400 pp., $45.00 (hardback), ISBN: 9780197567777.
Patrick Colm Hogan. Style in Narrative: Aspects of an Affective-Cognitive Stylistics. New York: Oxford University Press, 2021, 320 pp., $110 (hardback), ISBN: 9780197539576.
Steven Willemsen and Miklós Kiss, eds. Puzzling Stories: The Aesthetic Appeal of Cognitive Challenge in Film, Television and Literature. New York: Berghahn Books, 2022, $145.00 (hardback), ISBN: 9781800735910.
Sarah Tremlett. The Poetics of Poetry Film. Bristol: Intellect Books, 2021, 412 pp., $53.00 (paperback), ISBN: 9781789382686
Captopril versus enalapril in the protection of the gastric mucosa against NSAID induced gastric mucosal injury in rats
Authors: Matloub Samir Y. N. 
Published: October 2023

Background: Different mechanisms have been suggested for the development of nonsteroidal antiinflammatory drugs (NSAIDs) induced gastropathy. Angiotensin converting enzyme inhibitors have been suggested to have gastroprotective effects. This study investigates the gastroprotective effects of Angiotensin converting enzyme inhibitors, captopril and enalapril on indomethacin induced gastric mucosal damage in rats .Materials and methods: The study was conducted on 50 adult male albino rats, divided into 5 groups, the first served as a control received the vehicle , the second received indomethacin orally of 60mg/kg. The third and fourth groups were pretreated orally 30 minute prior indomethacin with either captopril or enalapril. In order to study the possible role of nitric oxide (NO) in the gastroprotective effect of captopril; intraperitoneal NG-L-Arginine Methyl Ester (L-NAME) a nitric oxide synthase inhibitor was given 30 minutes prior to captopril administration followed by indomethacin and this served as fifth group. The rats were then sacrificed after 4 hours and their stomachs were isolated and submitted to macroscopical assessment and for the measurement of the gastric prostaglandinE2 (PGE2), and myeloperoxidase (MPO).Results: Captopril in a dose of 15 mg/kg produced a significant reduction (p <0.05) in the gastric damage score .These protective effects were associated with a significant increase (p <0.05) in gastric PGE2 levels and marked decrease (p <0.05) in MPO activity, L-NAME pretreatment didn't abrogate the effects of captopril. Enalapril pretreatment failed to show the gastroprotective effects of captopril.Conclusions: The prophylactic use of captopril in this study prevented indomethacin induced gastropathy .This protective effect was associated with PGE2 upregulation and decreased oxyradical generation reflected by a decrease in MPO activity .Enalapril failed to produce the gastroprotective effects of captopril.
La suspensión de la sustanciación del proceso, una violación a los derechos de las víctimas de violencia intrafamiliar
Authors: Sarmiento Bermeo Lina Victoria , Torres Wilchez Marcelo 
Published: October 2023

Introducción: En el presente trabajo se analizó la pertinencia de la aplicación de la figura jurídica de la suspensión de la sustanciación del proceso en delitos de violencia contra la mujer o miembros del grupo familiar. Metodología: Esta investigación se proyectó en un enfoque cualitativo realizando una minuciosa revisión bibliográfica, además se aplicaron los métodos analítico - sintético, inductivo - deductivo, histórico – lógico y dogmático, así como las técnicas de revisión bibliográfica y la aplicación de la entrevista. Resumen: Luego del estudio crítico se justificó que, con la aplicación de la suspensión de la sustanciación del proceso, no existen garantías de que sea una petición voluntaria de la víctima, ya que no se desmiente que esta haya sido amenazada o condicionada por su agresor para que solicite la aplicación de dicha figura legal, constituyendo vulneración a derechos, tales como: el derecho a la integridad personal y a la reparación integral. Conclusiones: Adicionalmente se consideró que el juez competente debe solicitar la intervención de la oficina técnica para que realice informes sobre la condición de la víctima y miembros del grupo familiar para establecer el nivel de riesgo que puede correr la víctima y el juez pueda emitir su pronunciamiento en base a una realidad sobre dicha petición. Área de estudio general: Derecho, Área de estudio específica: Derecho Procesal.
Intra-Abdominal Testicular Seminoma In A Phenotypic Female: A Case of XY, Disorder of Sex Development Complicated with Seminoma
Authors: Abedin Nafisa , Bushrah Kazi Nabila , Muktadir Muhit Reza Md , Hossain Sajjad , Dey Bishnu Pada 
Published: October 2023

Disorder of sex development (DSD) complicated with seminoma is infrequently encountered in clinical practice. In order to diagnose the condition histopathological, immunohistochemical, and karyotype analysis can play the pivotal role. Additionally, prognosis of such patients largely depends upon the pathological staging at the time of initial diagnosis. Hence, the aim of this study was to determine the significance of macroscopic and microscopic examination together with immunohistochemical analysis in diagnosis and prognosis of XY, Disorder of sex development (DSD) which is often known to be complicated by intra-abdominal seminoma. A twenty eight year old patient was admitted into Bangabandhu Sheikh Mujib Medical University (BSMMU) presenting with a right sided adnexal mass for one year. Magnetic Resonance Imaging (MRI) showed a large lobulated soft tissue mass in right adnexal region accompanied by infantile uterus. Interestingly, chromosomal analysis of this patient was found to be 46 XY. Post-resection histological studies revealed an intra-abdominal seminoma at a stage of pT2NxMx. The tumour cells expressed immunoreactivity to both Placental Alkaline Phosphatase (PLAP) and C-kit.
Sir Salimullah Med Coll J 2023; 31: 60-64
Assessment of neutrophil NETs‑forming activity in patients with ulcerative colitis
Authors: Livzan M. A. , Bikbavova G. R. , Novikov D. G. , Zolotov A. N. , Kirichenko N. A. , Pakhtusova P. O. , Mikhaleva L. V. 
Published: October 2023

The aim of the study. To determine the non-tossing capacity of neutrophils in patients with ulcerative colitis (UC).Materials and methods. Ten patients with UC (study group) were included in the study; the control group consisted of 22 healthy volunteers of comparable age to the study group. All patients with UC received treatment according to clinical guidelines. We determined the non-tumorforming ability of the isolated neutrophil fraction in vitro in both groups using an original technique developed by members of the authors' team (Invention Patent No. 2768152 C 1; dated 23.03.2022. Application No. 2021129097 dated 06.10.2021).Results. In patients with UC, after 15 minutes of in vitro stimulation with probiotic, there was a statistically significant increase in early netosis cells (p < 0.010), cloud-like traps (p < 0.001) and filamentous NVLs (p < 0.001) compared with the control group. Bacterial uptake rate by neutrophil traps in UC patients was statistically significantly lower than in controls (p < 0.010).Conclusions. All identified features of neutrophils non-trapping capacity in UC patients may indicate changes in granulocyte reactivity, probably, under the influence of cytokines and/or due to therapeutic intervention. The neutrophil traps formed had fewer protective effects and probably more damaging effects. Studying the influence of the role of netosis on the course and prognosis of UC is a promising research area.
Comorbid patient with osteoporosis at doctor's appointment. What factors should be considered in selection of therapy
Authors: Strukov V. I. , Sergeeva-Kondrachenko M. Yu. , Vinogradova O. P. , Denisova A. G. , Moiseeva I. Ya. , Vikhrev D. V. , Poluboyarinov P. A. , Panina E. S. , Petrova E. V. , Fedorov A. V. , Burmistrova S. S. 
Published: October 2023

Relevance. Osteoporosis is a systemic disease of the skeleton, which is characterized by a decrease in bone mass per unit volume and a violation of the microarchitectonics of bone tissue, which leads to an increase in bone fragility and an increased risk of fractures.Target. The problems of comorbidity of osteoporosis and polypharmacy in the treatment of this disease are considered.Materials and methods. On the basis of the Center for Osteoporosis of the Penza Institute for Postgraduate Medical Education, a branch of the Russian Medical Academy of Continuing Postgraduate Education of Russia, we conducted an open, prospective, randomized study of the comorbid status of age-related patients with osteoporosis in order to improve the diagnosis and pathogenetic therapy of the disease. More than 1400 women took part in the study.The results of a study of the comorbid status of age-related patients with osteoporosis are presented. The expediency of antiresorptive therapy in comorbid patients with osteoporosis is discussed.Conclusions. The characteristics of osteoprotectors of a new generation based on the bioactive component of gonadotropic action are given, and the prospects of these agents in the implementation of a personalized approach in the treatment of osteoporosis, taking into account comorbidity and polypharmacy, are evaluated. Particular attention is paid to the problem of osteosarcopenia and its solution with the help of these osteoprotectors.
Reintegrating Vulnerable Youth in Jammu and Kashmir: A deradicalization process model by Maharashtra Police in India
Authors: Khaire Deepali 
Published: October 2023

Amidst the debate about India’s population dividend and India’s capability to harness it. The possible radicalization of youth in India can pose a significant challenge for India. The failure to achieve any durable peace in Jammu and Kashmir over three decades after the inception of the conflict has made it a multilayered complex issue. The unilateral action of the central government of removing Article 370 and bifurcating the former state of Jammu and Kashmir into two union territories will have long-term effects. Such development is juxtaposed with the surfacing trend of radicalization among youth in India and Jammu and Kashmir and joining ISIS. It becomes essential to suggest a more proactive rather than reactionary approach. The paper tries to draw on the insights from the Maharashtra Police Deradicalisation model and its utility for youth in Jammu and Kashmir.
Comparative efficacy of olaparib in combination with or without novel antiandrogens for treating metastatic castration-resistant prostate cancer
Authors: Chen Xiangyu , Pan Yang , Wang Qihua , Ren Congzhe , Li Muwei , Hao Xuexue , Xie Lijun , Liu Xiaoqiang 
Published: October 2023

BackgroundStudies using novel antiandrogens (NAA) in patients with metastatic castration-resistant prostate cancer (mCRPC) have shown overall survival benefit. As patients develop resistance to NAA therapy, the poly(ADP-ribose) polymerase inhibitor (PARPi) olaparib in combination with NAA may become a promising therapy. However the overall benefit of olaparib monotherapy or combination therapy still needs to be evaluated. Therefore, we performed a network meta-analysis to assess the efficacy and toxicity between olaparib, olaparib combined with abiraterone and NAA.MethodsWe searched PubMed, EMBASE, the Cochrane Library and American Society of Clinical Oncology (ASCO) University Meeting abstracts for randomized controlled trials reporting olaparib and NAA from 2010 up to March, 2023. Network meta-analysis using Stata 16.0 and R 4.4.2, hazard ratios (HR) with 95% confidence intervals (CI) were used to assess the results.ResultsFour trials reported olaparib, olaparib plus abiraterone and apalutamide plus abiraterone. radiographic progression-free survival (rPFS) was significantly lower in patients on apalutamide plus abiraterone compared to olaparib (HR, 1.43; 95% CI, 1.06-1.93). rPFS was similar for olaparib plus abiraterone and olaparib (HR, 1.35; 95% CI, 0.99-1.84); likewise, olaparib plus abiraterone and apalutamide plus abiraterone were similar (HR, 1.06; 95% CI, 0.83-1.35). In addition, there was no significant difference between the three interventions for OS. But olaparib has the highest probability of being a preferred treatment for improving rPFS and OS.ConclusionrPFS was in favor of olaparib compared with apalutamide plus abiraterone. But there were no difference between olaparib plus abiraterone and either olaparib or apalutamide plus abiraterone. Apalutamide plus abiraterone might be the most preferred intervention in cases where AEs are involved.Systematic review registrationhttps://inplasy.com, identifier INPLASY2023100072.
Cuproptosis in ccRCC: key player in therapeutic and prognostic targets
Authors: Lv Yang , Li Qiang , Yin Lu , He Shaohua , Qin Chao , Lu Zhongwen , Chen Hongqi 
Published: October 2023

BackgroundClassical biomarkers have been used to classify clear cell renal cell carcinoma (ccRCC) patients in a variety of ways, and emerging evidences have indicated that cuproptosis is closely related to mitochondrial metabolism, thereby accelerating the development and progression of ccRCC. Nevertheless, the specific relationship between cuproptosis and the prognosis and treatment of ccRCC remains unclear.MethodsWe comprehensively integrated several ccRCC patient datasets into a large cohort. Following that, we systematically analyzed multi-omics data to demonstrate the differences between two cuproptosis clusters.ResultsWe identified two cuproptosis clusters in ccRCC patients. Among the two clusters, cluster 1 patients showed favorable prognosis. We then confirmed the significant differences between the two clusters, including more typical cancer hallmarks were enriched in cluster 2 patients; cluster 2 patients were more susceptible to develop mutations and had a lower level of gistic score and mRNAsi. Importantly, both Tumor Immune Dysfunction and Exclusion analysis and subclass mapping algorithm showed that cuproptosis 1 patients were more susceptible to be responded to immunotherapy. In addition, a prognostic signature was successfully developed and also showed prominent predictive power in response to immunotherapy.ConclusionAs a result of our findings, we were able to classify ccRCC patients according to cuproptosis in a novel way. By constructing the cuproptosis clusters and developing the signature, patients with ccRCC could have a more accurate prognosis prediction and better immunotherapy options.
Patent ductus arteriosus shunting direction and diameter predict inpatient outcomes in newborns with congenital diaphragmatic hernia
Authors: Bao Min , Wu Tao , Guo Jinghui , Wang Ying , Cao Aimei , Liu Chao , Wei Yandong , Zheng Chunhua , Shi Lin , Ma Lishuang 
Published: October 2023

ObjectiveTo evaluate whether the patent ductus arteriosus (PDA) can serve as a predictive factor for inpatient outcomes in congenital diaphragmatic hernia (CDH) patients.MethodsA retrospective cohort study was conducted on 59 CDH patients at the Capital Institute of Pediatrics from January 2020 to August 2022. Echocardiography was performed at least three times: within 2–3 h after birth, pre-operatively, and post-operatively of CDH surgery. Based on the direction of the PDA shunt in the first echocardiogram, patients were classified into three groups: left-to-right shunting or closed PDA (L-R), bi-directional shunting, and right-to-left shunting (R-L).ResultsThe mortality rate was 15.3% (9/59), with all non-survivors having R-L shunting and group mortality of 39.1% (9/23). The direction of the PDA shunt was significantly associated with the duration of ventilation and length of hospital stay (p &lt; 0.05). Decreased PDA diameter or pre-operative shunting direction change towards L-R or bi-directional shunting were associated with higher survival rates, while increased PDA diameter or continuous R-L shunting were associated with higher mortality rates. Pre-operative PDA shunt direction, PDA size after birth and before surgery, gestational age of diagnosis, and shortening fraction before surgery were significantly correlated with patient outcomes. The direction of the preoperative PDA shunt was the most relevant factor among these relationships (p = 0.009, OR 20.6, CI 2.2∼196.1).ConclusionOur findings highlight the importance of monitoring changes in PDA shunt directionality and diameter in the early stage after birth, as these parameters may serve as valuable predictors of patient outcomes.
Application timing and duration of LED and HPS supplements differentially influence yield, nutrient bioaccumulation, and light use efficiency of greenhouse basil across seasons
Authors: Hammock Hunter A. , Kopsell Dean A. , Sams Carl E. 
Published: October 2023

Three primary factors that impact plant growth and development are light quantity, quality, and duration. Commercial growers can manipulate these parameters using light-emitting diodes (LEDs) to optimize biomass yield and plant quality. There is significant potential to synergize supplemental lighting (SL) parameters with seasonal variation of ambient sunlight to optimize crop light use efficiency (LUE), which could increase biomass while reducing SL electricity costs. To determine the best lighting characteristics and durations for different crops, particularly for enhancing the yield and nutritional quality of high-value specialty crops produced in greenhouses during the winter, a thorough efficacy comparison of progressive incremental daily light integrals (DLIs) using LED and high-pressure sodium (HPS) sources is required. The purpose of this study was to compare the effects of differential application timing and DLIs of supplemental blue (B)/red (R) narrowband wavelengths from LED lighting systems and HPS lamps on greenhouse hydroponic basil (Ocimum basilicum var. Genovese) production. We assessed edible biomass, nutrient bioaccumulation, and LUE. Nine light treatments included: one non-supplemented natural light (NL) control, two end-of-day (EOD) HPS treatments applied for 6 h and 12 h, five EOD 20B/80R LED treatments applied for 3 h, 6 h, 9 h, 12 h, 18 h, and one continuous LED treatment (24 h). Each SL treatment provided 100 µmol·m-2·s-1. The DLI of the NL control averaged 9.9 mol·m-2·d-1 during the growth period (ranging from 4 to 20 mol·m-2·d-1). SL treatments and growing seasons significantly impacted biomass and nutrient bioaccumulation; some SL treatments had lower yields than the non-supplemented NL control. January growing season produced the lowest fresh mass (FM) and dry mass (DM) values compared to November, which had the highest. Mineral analyses revealed that both growing seasons and lighting types impacted macro and micronutrient accumulation. Additionally, the efficiency of each treatment in converting electrical energy into biomass varied greatly. EOD supplements using LED and HPS lighting systems both have merits for efficiently optimizing yield and nutrient accumulation in basil; however, biomass and nutrient tissue concentrations highly depend on seasonal variation in ambient sunlight in conjunction with a supplement’s spectral quality, DLI, and application schedule.
Psychometric properties of the affect integration inventory – short form in a sample of patients with personality disorder
Authors: Frederiksen Christina , Kjaersdam Telléus Gry , Solbakken Ole André 
Published: October 2023

IntroductionAffect integration comprises the capacity to access and utilize the motivational and signal properties of affects. This capacity is essential for personal adjustment, mental health, and well-being. Affect integration is commonly operationalized through the Affect Integration Inventory. This study examines the psychometric properties of a short-form (AII-SF-42) of the instrument in a sample of patients with personality disorders (n = 87).MethodsAnalyses of internal-consistency reliability, along with standardized mean differences-, and associations between short- and long-forms are reported. Internal structure was assessed by confirmatory factor analyses and external criterion validity was addressed by tests of associations between the AII-SF-42-scale scores and measures of alexithymia, symptom distress, interpersonal problems and level of personality dysfunction.ResultsThe study demonstrated satisfactory reliability and validity for scores derived from the AII-SF-42, including acceptable internal consistency and strong correspondence with long-form scores, a consistent factor structure organized according to discrete affects, and systematic patterns of convergent and discriminant associations with external measures.ConclusionTaken together, the results of the study demonstrate that in clinical settings, including patients with personality disorders the AII-SF-42 is a valid and useful alternative to the full-length version of the instrument.