bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cannabis sativa (hemp) – an eco-friendly material for heritage conservation and sustainable environment
Authors: Singh Manager Rajdeo , Kanth Aditya Prakash , Sawant Madhuri , Ragde Rajesh 
Published: February 2024

PurposeThe present work highlights the outstanding properties of Cannabis sativa that can be harnessed for various utilitarian functions and its climate friendly properties.Design/methodology/approachIn this paper, the authors reviewed current research on all possible utilities from household work to manufacturing of various products that are environmentally sustainable. The authors have presented some of their research on this materials and also exploration of hemp as an archaeological material based on the findings from wall paintings of Ellora caves.FindingsThere are references of hemp use in mixing with earthen/lime plaster of western Indian monuments. Around 1,500 years of Ellora’s earthen plaster, despite harsh climatic conditions, survived due to the presence of hemp in the plaster that adds durability, fibrosity and its capacity to ward off insects and control humidity. Furthermore, the outstanding quality of Cannabis as carbon sequestrant was harnessed by Indians of ancient times in Ellora mural paintings.Research limitations/implicationsThis work discusses some relevant literature on the potential use of hempcrete aligned with Agenda 2030 of sustainable development goals.Practical implicationsThere are several research going on in producing sustainable materials using hemp that have the least environmental impact and can provide eco-friendly solutions.Social implicationsThe authors impress upon the readers about multifarious utility of the hemp and advices for exploration of this material to address many environmental issues.Originality/valueThis paper presents both review of the existing papers and some components coming directly from their laboratory investigations.
Psychologically gaining through losing: a metaphor analysis
Authors: Du Plessis Linda , Bui Hong T.M. 
Published: February 2024

PurposeThis paper conceptualises how managers psychologically experience and respond to crises via metaphor analysis.Design/methodology/approachThis paper uses a discourse dynamics approach to metaphor analysis. Conceptual metaphors were analysed and developed into concept maps through 37 semi-structured interviews with senior managers from different portfolios within 16 public universities in South Africa after #FeesMustFall protests.FindingsFive domains emerged, including (1) looming crisis, (2) crisis onset, (3) crisis triage and containment, (4) (not) taking action and (5) post-crisis reflection. These domains shape a framework for the crisis adaptation cycle.Practical implicationsThis study suggests that organisations should pay more attention to understanding emotions in crises and can use the adaptation model to develop their managers. It shows how metaphors can help explain affective and cognitive experiences and how emotions shift and evolve during a crisis. Managers should be aware of early signs of the crisis and its potential impact on their business operation in the looming and recognition stages, analyse the situation and work collectively on possible actions to minimise losses and maximise gains.Originality/valueThis is a rare investigation into the emotions of senior managers in the public sector in a social movement and national crisis via unconventional research methods to advance cognitive appraisal theory in crisis management.
Prescriptive digital transformation maturity model: a development and validation study
Authors: Kocaoglu Batuhan , Kirmizi Mehmet 
Published: February 2024

PurposeThis study aims to develop a modular and prescriptive digital transformation maturity model whose constituent elements have conceptual integrity as well as reveal the priority weights of maturity model components.Design/methodology/approachA literature review with a concept-centric analysis enlightens the characteristics of constituent parts and reveals the gaps for each component. Therefore, the interdependency network among model dimensions and priority weights are identified using decision-making trial and evaluation laboratory (DEMATEL)-based analytic network process (ANP) method, including 19 industrial experts, and the results are robustly validated with three different analyses. Finally, the applicability of the developed maturity model and the constituent elements are validated in the context of the manufacturing industry with two case applications through a strict protocol.FindingsResults obtained from DEMATEL-based ANP suggest that smart processes with a priority weight of 17.91% are the most important subdimension for reaching higher digital maturity. Customer integration and value, with a priority weight of 17.30%, is the second most important subdimension and talented employee, with 16.24%, is the third most important subdimension.Research limitations/implicationsThe developed maturity model enables companies to make factual assessments with specially designed measurement instrument including incrementally evolved questions, prioritize action fields and investment strategies according to maturity index calculations and adapt to the dynamic change in the environment with spiral maturity level identification.Originality/valueA novel spiral maturity level identification is proposed with conceptual consistency for evolutionary progress to adapt to dynamic change. A measurement instrument that is incrementally structured with 234 statements and a measurement method that is based on the priority weights and leads to calculating the maturity index are designed to assess digital maturity, create an improvement roadmap to reach higher maturity levels and prioritize actions and investments without any external support and assistance.
Bibliometric mapping in the landscape of cybernetics: insights into global research networks
Authors: Nica Ionut 
Published: February 2024

PurposeThis bibliometric mapping study aimed to provide comprehensive insights into the global research landscape of cybernetics. Utilizing the biblioshiny function in R Studio, we conducted an analysis spanning 1958 to 2023, sourcing data from Scopus. This research focuses on key terms such as cybernetics, cybernetics systems, complex adaptive systems, viable system models (VSM), agent-based modeling, feedback loops and complexity systems.Design/methodology/approachThe analysis leveraged R Studio’s biblioshiny function to perform bibliometric mapping. Keyword searches were conducted within titles, abstracts and keywords, targeting terms central to cybernetics. The timespan, 1958–2023, provides a comprehensive overview of the evolution of cybernetics-related literature. The data were extracted from Scopus to ensure a robust and widely recognized source.FindingsThe results revealed a rich and interconnected global research network in cybernetics. The word cloud analysis highlights prominent terms such as “agent-based modeling,” “complex adaptive systems,” “feedback loop,” “viable system model” and “cybernetics.” Notably, the journal Kybernetes has emerged as a focal point, with significant citations, solidifying its position as a key source within the cybernetics research domain. The bibliometric map provides visual clarity regarding the relationships between various concepts and their evolution over time.Originality/valueThis study contributes original insights by employing advanced bibliometric techniques in R Studio to map the cybernetics research landscape. The comprehensive analysis sheds light on the evolution of key concepts and the global collaborative networks shaping cybernetics research. The identification of influential sources, such as Kybernetes, adds value to researchers seeking to navigate and contribute to the dynamic field of cybernetics. Furthermore, this study highlights that cybernetics not only provides a useful framework for understanding and managing major economic shocks but also offers perspectives for understanding phenomena in various fields such as economics, medicine, environmental sciences and climate change.
Efficacy and safety of epidural block with lidocaine for refractory severe plaque psoriasis: An open‐label pilot study in real world setting
Authors: Xu Xin , Yu Buwei , Lv Youwen , Cai Qing , Li Mengya , Li Guifeng , Li Qifang 
Published: February 2024

AbstractEpidural block using lidocaine, a non‐selective blocker of voltage‐gated sodium channels (Nav), has demonstrated efficacy in the treatment of severe plaque psoriasis in a limited number of cases. This study aimed to evaluate the effectiveness and safety of epidural lidocaine block in adult patients with severe, treatment‐resistant plaque psoriasis. This was an open‐label pilot study. Patients with severe plaque‐type psoriasis unresponsive to at least one systemic treatment were enrolled for a 1‐week epidural lidocaine block and followed up for 48 weeks. Thirty‐six patients participated, with 32 completing the study. At the 12‐week mark, there was a remarkable 59% improvement in the mean Psoriasis Area Severity Index (PASI) score (P < 0.001). By week 48, 28 out of 32 patients (87%) achieved PASI 75, while 18 out of 32 (56%) reached PASI 90. Within 7 days, 20 out of 21 patients (95%) reported a reduction in itch, with a mean itch reduction of 82% at day 1 and 94% at day 7. Notably, no severe side effects were observed. Epidural lidocaine block proved to be an effective and safe long‐term treatment option for individuals with refractory severe plaque psoriasis.
Synergic actions of botulinum neurotoxin A and oxaliplatin on colorectal tumour cell death through the upregulation of TRPM2 channel‐mediated oxidative stress
Authors: Demir Sıdıka , Duman İpek , Nazıroğlu Mustafa 
Published: February 2024

AbstractBotulinum neurotoxin A (BoNT) is being shown to have anticancer action as a potential adjuvant treatment. The transient receptor potential (TRP) melastatin 2 (TRPM2) stimulator action of BoNT was reported in glioblastoma cells, but not in colorectal cancer (HT29) cells. By activating TRPM2, we evaluated the impacts of BoNT and oxaliplatin (OXA) incubations on oxidant and apoptotic values within the HT29 cells. Control, BoNT (5 IU for 24 h), OXA (50 μM for 24 h) and their combinations were induced. We found that TRPM2 protein is upregulated and mediates enhanced BoNT and OXA‐induced Ca2+ entry in cells as compared to control cells. The increase of free reactive oxygen species (ROS), but the decrease of glutathione is the main ROS responsible for TRPM2 activation on H29 exposure to oxidative stress. BoNT and OXA‐mediated Ca2+ entry through TRPM2 stimulation in response to H2O2 results in mitochondrial Ca2+ overload, followed by mitochondrial membrane depolarization, apoptosis and caspase‐3/‐8/‐9, although they were diminished in the TRPM2 antagonist groups (N‐(p‐amylcinnamoyl)anthranilic acid and carvacrol). In conclusion, by increasing the susceptibility of HT29 tumour cells to oxidative stress and apoptosis, the combined administration of BoNT and OXA via the targeting of TRPM2 may offer a different approach to kill the tumour cells.
Expression pattern analysis of transmembrane receptor TmToll‐8, −9, and −10 in the coleopteran insect Tenebrio molitor following systemic infection
Authors: Kojour MaryamAli Mohammadie , Jang Ho Am , Vasantha‐Srinivasan Prabhakaran , Lee Yong Seok , Jo Yong Hun , Han Yeon Soo 
Published: February 2024

AbstractIn insects, the production of antimicrobial peptides is considered to be the solo arm of the innate immune response. The Toll and immune deficiency pathways are two major signaling pathways that lead to the production of antimicrobial peptides as final effectors. The dynamic functions of Toll/Toll‐like receptors have been thoroughly reviewed in mammals and Drosophila. During the last decade, we have attempted to clarify the immunological roles of different Toll receptor variants and their ligands in Tenebrio molitor. Accordingly, we showed that TmToll‐8, −9, and −10 mRNA transcripts are induced following systemic injections of Gram‐negative, Gram‐positive, and fungal infections. Our data revealed harmonic expression patterns of TmToll‐8, −9, and −10 throughout the developmental stages of healthy individuals and in response to infections in the examined tissues (Malpighian tubules, gut, fat bodies, and hemolymph), illustrating similar evolutionary conversions of different Toll receptor variants in T. molitor. Taken together, our findings highlight the immunological actions of TmToll‐8, −9, and −10 in response to pathogenic insults in T. molitor.
Distribution of the N2‐fixing cyanobacterium Candidatus Atelocyanobacterium thalassa in the Mexican Pacific upwelling system under two contrasting El Niño Southern Oscillation conditions
Authors: Vieyra‐Mexicano Cinthya , Souza Valeria , Pajares Silvia 
Published: February 2024

AbstractThe unicellular cyanobacterium Candidatus Atelocyanobacterium thalassa (UCYN‐A) is a key diazotroph in the global ocean owing to its high N2 fixation rates and wide distribution in marine environments. Nevertheless, little is known about UCYN‐A in oxygen‐deficient zones (ODZs), which may be optimal environments for marine diazotrophy. Therefore, the distribution and diversity of UCYN‐A were studied in two consecutive years under contrasting phases (La Niña vs. El Niño) of El Niño Southern Oscillation (ENSO) along a transect in the ODZ of the Mexican Pacific upwelling system. Of the three UCYN‐A sublineages found, UCYN‐A1 and UCYN‐A3 were barely detected, whereas UCYN‐A2 was dominant in all the stations and showed a wide distribution in both ENSO phases. The presence of UCYN‐A was associated with well‐oxygenated waters, but it was also found for the first time under suboxic conditions (<20 μM) at the bottom of a shallow coastal station, within the oxygen‐poor and nutrient‐rich Subsurface Subtropical water mass. This study contributes to the understanding of UCYN‐A distribution under different oceanographic conditions associated with ENSO phases in upwelling systems, especially because of the current climate change and increasing deoxygenation in many areas of the world's oceans.
Simón Rodríguez and the sentimental roots of social republicanism
Authors: Castrillón Alejandro 
Published: February 2024

AbstractIn this article, I claim that Simón Rodríguez, a 19th‐century Venezuelan thinker, used and reconfigured Jean‐Jacques Rousseau's understanding of amour‐propre to construct a new political foundation for Latin America. He sought to channel it and other sentiments toward productive ends with a social education. In doing so, Rodríguez departs from Rousseau while still addressing the latter's political concerns regarding the benefits of egalitarian republicanism and the pitfalls of civilizational progress. Instead of accepting political models from antiquity, Rodríguez conceives of an egalitarian social republic uniting the rich and poor, White and people of color. While skeptical of European civilization built on commerce, he sees the possibility of a social civilization reconciling the interests of all in society. This comparative study of Rodríguez provides a necessary addition to the history of political philosophy while offering insights into a mode of thinking still informing contemporary politics in Latin America.
Hand eczema‐related presenteeism and sickness absence: A cross‐sectional population‐based study
Authors: Brands Marjolein J. , Loman Laura , Roelen Corné A. M. , Bültmann Ute , Schuttelaar Marie L. A. 
Published: February 2024

AbstractBackgroundTo date, hand eczema (HE)‐related presenteeism has never been assessed within the general population, and general population‐based studies on HE‐related sickness absence are limited.ObjectivesTo assess the prevalence of HE‐related presenteeism and sickness absence, and factors associated with HE‐related presenteeism, within the Dutch general population.MethodsWithin the Lifelines Cohort Study, participants with HE in the last year (aged 18–65 in 2020), were identified by a questionnaire including questions regarding HE‐related presenteeism and sickness absence. Socio‐demographic factors were collected from 2006 to 2020.ResultsOut of the 3.703 included participants with HE, 2.7% (n = 100) reported HE‐related presenteeism, with 19.8% (n = 57) among those with severe‐to‐very‐severe HE. HE‐related sickness absence was reported by 0.5% (n = 20) and 5.9% (n = 17), respectively. Logistic regression analyses, adjusted for age and sex, showed negative associations between HE‐related presenteeism and higher educational attainment, higher income (>€2500) and higher occupational skill level, and positive associations for high‐risk occupations, chronic HE, moderate and severe‐to‐very‐severe HE (compared to almost clear), atopic dermatitis and occupational wet exposure.ConclusionsA high prevalence of HE‐related presenteeism was found among participants with severe‐to‐very‐severe HE. Future studies should focus on longitudinal associations with the clinical course of HE, as HE‐related presenteeism might aggravate symptoms of HE.
Effect of comprehensive nursing care for the liver cancer patients undergoing interventional therapy in China: A systematic review and meta‐analysis
Authors: Zhang Shimei , Li Na , Mao Xuying , Yang Dongxia 
Published: February 2024

AbstractAimsThis review aims to assess the effect of comprehensive nursing care on liver cancer patients undergoing interventional therapy in China.MethodsIn accordance with PRISMA guidelines, we reviewed randomized controlled trials and observational studies assessing the effect of comprehensive nursing care against standard care on liver cancer patients undergoing specific interventional therapies in China, including PubMed, Embase, CENTRAL and CINAHL till June 2023. Data synthesis was conducted using a random‐effects model and reported as pooled odds ratio (OR) or mean difference (MD) or standardized mean differences (SMD).ResultsTen Chinese studies with 1682 participants were evaluated. Comprehensive nursing care significantly enhanced patient outcomes in liver cancer treatment. Quality of life improved markedly (OR: 0.16, 95% CI: 0.06–0.41). Notable reductions were observed in anxiety (MD: −8.96, 95% CI: −11.52 to −6.40) and depression (MD: −9.47, 95% CI: −11.79 to −7.14). Patients also experienced increased physical (SMD: 1.70, 95% CI: 1.15–2.25), social (SMD: 1.65, 95% CI: 1.14–2.16) and activity scores (SMD: 1.94, 95% CI: 1.49–2.39), alongside a decrease in post‐treatment complications (OR: 0.28, 95% CI: 0.21–0.37), demonstrating the multifaceted benefits of comprehensive care.ConclusionComprehensive nursing care may improve patient outcomes in liver cancer treatment, offering potential benefits in reducing the side effects of interventional therapy.
Heart failure and the cost of dying: must the ferryman always be paid?
Authors: Sivanathan Vithoosharan , Smallwood Natasha , Ong Jeffrey , Wee Elin , Zentner Dominica 
Published: February 2024

AbstractBackgroundProvision of palliative care in chronic heart failure (CHF) can support complex decision‐making, significantly improve quality of life and may lower healthcare costs.AimsTo examine whether healthcare costs differed in terminal admissions according to the adoption of a palliative approach.DesignRetrospective review of medical records and costing data for all admissions resulting in death from CHF (July 2011 to December 2019), analysed as two groups (2011–2016 and 2016–2019) because of background changes in costings.SettingAdmissions with CHF resulting in death in an Australian tertiary referral centre.ResultsThe cohort (n = 439) were elderly (median age 83.7 years, interquartile range (IQR) = 77.6–88.7 years) and mostly men (54.9%). Half (230, 52.4%) were referred to a specialist palliative care team, whereas over a third (172, 39.2%) received a palliative approach. Receiving a palliative approach was associated with a nonstatistically significant lower admission cost (AU$12 710 vs AU$15 978; P = 0.19) between 2011 and 2016 (n = 101, 38.8%) and a significantly lower cost (AU$11 319 vs AU$15 978; P < 0.01) between 2016 and 2019 (n = 71, 39.7%). Intensive care admission resulted in the single greatest additional cost at AU$14 624 (IQR = AU$4130–AU$44 197) (n = 48, 2011–2016). Median terminal admission cost was lower for patients with comfort goals of care (P < 0.01), without life‐sustaining interventions (P < 0.01) or who received a palliative approach (P < 0.01).Referral to inpatient specialist palliative care or receiving a palliative approach resulted in comparable admission costings (AU$11 621 [IQR = AU$4705–AU$32 457] and AU$11 466 [IQR = AU$4973–AU$25 614]).ConclusionA palliative approach in terminal CHF admission may improve quality at the end of life and decrease costs associated with care.
Instructor's low guided gaze duration improves learning performance for students with low prior knowledge in video lectures
Authors: Shi Yawen , Chen Zengzhao , Wang Mengke , Chen Shaohui , Sun Jianwen 
Published: February 2024

AbstractBackgroundGuided gaze is the instructor's gaze towards teaching materials to guide students' attention, and it plays a vital role in enhancing video‐based education. The duration of guided gaze, indicating how long instructors focus on teaching materials, varies based on the lecture design. Nevertheless, the impact of varying durations of guided gaze, especially concerning students' prior knowledge, remains inadequately understood.ObjectivesThis study investigates the influence of the instructor's guided gaze duration and students' prior knowledge on learning performance and affective experiences in video lectures.Methods145 fifth‐grade students participated and were divided into high and low prior knowledge groups based on a pre‐test. Within each group, students were randomly assigned to view one of three video lectures with different guided gaze durations (high vs. medium vs. low). Learning performance and affective experiences (learning experience, satisfaction, and emotions) were measured as dependent variables.Results and ConclusionThe results revealed that low guided gaze duration significantly improves learning performance for students with low prior knowledge. Conversely, high guided gaze duration negatively impacts learning experience, satisfaction, and positive emotions. Additionally, students with high prior knowledge reported higher learning experience and satisfaction. These findings highlight the interaction between guided gaze duration and prior knowledge in students' learning performance.ImplicationsOur findings provide valuable implications for the design of guided gaze duration in video lectures based on students' prior knowledge. By adjusting guided gaze duration appropriately, instructors can optimise students' learning performance and affective experiences.