bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post-Jungian perspectives on archetypes of individuation in Aldous Huxley’s <i>Brave new world</i> and <i>Island</i>
Authors: Bessa Maria de Fátima de Castro 
Published: January 2025

The archetypes of individuation, as proposed by C. G. Jung, have been challenged by post-Jungian writers. Persona, shadow, anima and self offer examples of these new approaches, and their use in the analysis of Aldous Huxley’s Brave New World and Island highlight some cultural aspects of the novels.
O gênero problemático na obra de Álvares de Azevedo
Authors: Werkema Andréa Sirihal 
Published: January 2025

Este ensaio discute a prática da fusão dos gêneros literários na obra de Álvares de Azevedo, com ênfase em seu drama Macário. Tal prática aponta para a inserção de Azevedo em um Romantismo preocupado com uma discussão propriamente estética, para além da obrigatoriedade das discussões nacionalistas em nosso Romantismo.
VIOLÊNCIA, RESSENTIMENTO E COMPREENSÃO NAS MEMÓRIAS DE GRACILIANO RAMOS
Authors: Ribeiro Gustavo Silveira 
Published: January 2025

Este trabalho apresenta uma interpretação de Infância, de Graciliano Ramos, tendo como centro o debate ético que atravessa a obra. Considerado pessimista pela crítica, o texto foi lido quase sempre a partir das mesmas questões: violência, medo, ressentimento. Realizando movimento contrário, procurei expor a tese de que predomina no livro uma visão menos negativa do homem e do mundo.
Manejo posoperatorio en caso de extrusión de cemento sellador: reporte de un caso
Authors: Soria Sánchez Fabián Giovanny , Kun Astudillo Kenia Karen 
Published: January 2025

Introducción: La lesión del nervio alveolar inferior (NAI) representa una complicación grave del tratamiento endodóntico, ya que, debido a la sobreinstrumentación de los conductos, una extrusión posterior de agentes irrigantes, y la sobreextensión de material de obturación podría darse la posibilidad de una perforación del conducto alveolar inferior lo que puede provocar una lesión del NAI y comprometer el éxito del tratamiento. Descripción del caso: Se presenta el caso clínico de una mujer de 41 años, que asistió a la clínica de la Facultad de Odontología de la Universidad de Cuenca, presentaba dolor de la pieza 4.7, al examen clínico y radiográfico se observó una lesión cariosa distal próxima al cuerno pulpar y una restauración con filtración. Se diagnosticó una pulpitis irreversible sintomática y se inició el tratamiento endodóntico en el que se utilizó un cemento de resina epóxica AH Plus y una técnica de obturación termoplastificada. Al finalizar la obturación, la paciente refirió dolor intenso, por tal motivo se tomó una radiografía periapical y se observó una extrusión de sellador a nivel del conducto del nervio dentario inferior. Se estableció el diagnóstico de lesión del nervio alveolar inferior por extrusión de cemento sellador, por lo que se procedió a controlar la sintomatología mediante un tratamiento farmacológico. Conclusión: Gracias a la terapia farmacológica con Prednisona se pudo controlar el dolor que refirió la paciente hasta su completa recuperación sin la necesidad de llegar a una terapia neuroquirúrgica.
The Pivotal Role of Management Control in Times of Crisis: Enhancing Organizational Resilience and Strategic Adaptation
Authors: Snoussi Nabila , Elhamma Azzouz 
Published: January 2025

This article examines the transformation of management control, which has traditionally been regarded as a support function, into a central strategic lever in times of crisis. The study is focused on three core areas: the impact of management control mechanisms on organisational performance; their role in facilitating adaptation in a crisis context; and the influence of adopting new control tools on the company’s strategic direction. The research utilises a quantitative approach and is based on a sample of 97 companies across various sectors and sizes, ensuring diverse representation via non-stratified random sampling. Statistical techniques employed include Wilcoxon Signed-Rank Tests, quantile regression, and Spearman's correlation coefficients to validate the hypotheses. The findings demonstrate that management control is a key factor in enhancing performance, organisational resilience, and the implementation of a proactive strategy. Specifically, advanced technologies such as artificial intelligence (AI) and enterprise resource planning (ERP) systems were shown to enable companies to anticipate risks, seize opportunities, and strengthen their competitive advantage during crises. However, several limitations remain. These include the relatively small sample size, which restricts generalizability, the specific nature of the crises under study (COVID-19 crisis) and the potential for respondent bias, as most participants were senior executives or management controllers. These factors highlight the need for further research, particularly the exploration of additional crisis contexts and the use of mixed methodologies for a more comprehensive analysis.
Étude Exploratoire des Motivations au Choix de la Carrière Salariale chez des Etudiants de l’université Félix Houphouët Boigny d’Abidjan (Côte d’Ivoire)
Authors: Edoua Kassi Edoua David Samuel 
Published: January 2025

Le présent travail vise à connaitre les motivations au salariat afin d’expliquer l’opiniâtreté de certains jeunes diplômés à obtenir un emploi salarié. Il a eu recours à une approche qualitative (l’analyse de contenu thématique) passant par des entretiens semi-directifs conduit auprès de 36 étudiants inscrits en année de Master et provenant de 9 facultés. Les participants de l’étude ont été sélectionnés grâce à la technique d’échantillonnage par cas multiples. Les résultats révèlent que 08 sous-catégories de raisons expliquent les motivations au salariat. 78 % de ces motivations émanent de ceux ayant choisi le salariat comme carrière professionnelle et 22 %, de ceux ayant opté pour la carrière entrepreneuriale. Ainsi, les résultats montrent qu’ici c’est plutôt les attitudes cognitives puis, les traits de personnalité qui prédominent dans le choix de la carrière salariale. De fait, les décideurs et spécialistes engagés dans la promotion de l’insertion professionnelle doivent s’intéresser aux dispositions individuelles, aux représentations mentales et sociales des étudiants relatifs au salariat. Une modification réussie des schémas de pensées sur le salariat permettrait aux États de rééquilibrer la balance de l’orientation professionnelle et aussi, aux jeunes diplômés de sortir le plus rapidement possible des longues quêtes d’emploi et du chômage.

The aim of this study is to find out what motivates some young graduates to take up salaried employment in order to explain their persistence. A qualitative approach (thematic content analysis) was used, involving semi-directive interviews with 36 students enrolled in a Master's year from 9 faculties. Participants in the study were selected using a multiple-case sampling technique. The results reveal that 08 sub-categories of reasons were found to explain students' motivations for taking up paid employment. 78 % of these reasons were given by those who had chosen to work for a company as a professional career and 22 % by those who had opted for an entrepreneurial career. The results show that in this case, it is cognitive attitudes and then personality traits that predominate in students' choice of salary career. As a result, decision-makers and specialists working in the field of professional integration must take an interest in the individual dispositions and mental and social representations of students with regard to salaried employment. Achieving a change in thinking about salaried employment would not only enable states to rebalance the balance of career guidance but also enable young graduates to emerge as quickly as possible from the long search for work and unemployment.
Tri phytochimique et activité antioxydante in vitro des extraits de Bombax brevicuspe (Sprague) Roberty(Malvaceae) une plante médicinale utilisée dans le traitement de la fistule obstétricale en Côte d'Ivoire
Authors: Marianne Lagou Stéphanie , Marius Lébri , Honora Tra Bi Fézan , Witabouna Koné Mamidou , Chigr Fatiha , Abderrafia Hafid , Mostafa Khouili 
Published: January 2025

Bombax brevicuspe (Sprague) Roberty (Malvaceae) est une plante médicinale utilisée dans le traitement traditionnel de la fistule obstétricale en Côte d'Ivoire. Cette étude a pour but d’évaluer l’activité antioxydante in vitro des extraits de l’écorce de B. brevicuspe. Les différents extraits (aqueux, éthanol, acétate d’éthyle et hexane) de l’écorce de B. brevicuspe ont été obtenus par décoction et par macération. Après le screening phytochimique, l‘activité antiradicalaire des extraits à différentes concentrations a été déterminée par le test du DPPH et les pourcentages d’inhibition du DPPH (IC50) ont été calculés. Le screening phytochimique a montré que l’écorce de B. brevicuspe est riche en groupes chimiques naturelles (alcaloïdes, flavonoïdes, tanins, coumarines, stérols, triterpénoïdes et saponines). Tous les extraits ont montré une activité antioxydante en piégeant les radicaux libres DPPH selon la concentration. Il a été enregistré une augmentation des valeurs IC50 de (5 à 60µg/ml). L'extrait hexanique a montré une IC50 (5 µg/mL) proche de la vitamine C (4,5µg/ml). Les résultats obtenus suggèrent que les extraits de l’écorce de tige B. brevicuspe contiennent plusieurs groupes chimiques et présentent une activité antioxydante au test du DPPH.
Bombax brevicuspe (Sprague) Roberty (Mallvaceae) is a medicinal plant used in the traditional treatment of obstetric fistula in Côte d'Ivoire. The purpose of this study is to evaluate the in vitro antioxidant activity of B. brevicuspe bark extracts. The various extracts (aqueous, ethanol, ethyl acetate and hexane) of the bark of B. brevicuspe were obtained by decoction and maceration. After phytochemical screening, the anti-radical activity of the extracts at different concentrations was determined by the DPPH test and the percentages of DPPH inhibition (IC50) were calculated. Phytochemical screening has shown that the bark of B. brevicuspe is rich in natural chemical groups (alkaloids, flavonoids, tannins, coumarins, sterols, triterpenoids and saponins). All extracts showed antioxidant activity by scavenging DPPH free radicals depending on concentration. An increase in IC50 values of (60 to 5 μg/ml) was recorded. The hexanic extract showed an IC50 (5 μg/mL) close to vitamin C (4.5 μg/ml). The results obtained suggest that Bombax brevicuspe extracts contain several chemical groups and exhibit antioxidant activity in the DPPH test.
Message from the Winners
Authors:   Editorial Office
Published: January 2025

Message from the Winner, Norio Maki
Message from the Winner, T. Sontayasara, S. Jariyapongpaiboon, A. Promjun, N. Seelpipat, K. Saengtabtim, J. Tang, and N. Leelawat
Message from the Winner, Miho Ohara
Message from the Winner, Hisaya Sawano
Message from the Winner, Reo Kimura
Investigating molecular mechanisms in ischemic preconditioning-induced resiliency to severe acute global cerebral ischemia using a mouse model of chronic cerebral hypoperfusion
Authors: Kushwaha Roli , Patel Shashikant , KS Yuvaraj , Sharma Pooja , Kumar Arvind , Chakravarty Sumana 
Published: January 2025

Abstract

Cerebral ischemic preconditioning offers a promising strategy to enhance resilience to severe ischemic insults. Unilateral common carotid artery occlusion (UCCAo) is a valuable model to simulate chronic cerebral hypoperfusion (CCH). This study explored UCCAo induced CCH as a preconditioning stimulus to induce ischemic tolerance against transient global cerebral ischemia (tGCI) induced by bilateral common carotid artery occlusion (BCCAo) in both male and female mice. We evaluated the effects of CCH preconditioning on neuroprotection and recovery through behavioral, histopathological, and molecular analyses. Laser Doppler Imaging (LDI) confirmed significant cerebral hypoperfusion post-UCCAo. Preconditioning reduced mortality rates at day 1 and 7 post surgery as compared to BCCAo, suggesting its neuroprotective potential. Neurodeficit scoring demonstrated significant protection in preconditioned animals with recovery aligning closer to sham controls. Behavioral assays revealed improved motor and cognitive outcomes in preconditioned groups, with sex-specific differences evident in recovery dynamics. Molecular analyses indicated reduced reactive astrocyte (GFAP) and microglial (IBA1) activation in preconditioned animals, reflecting controlled glial responses. Sex-dependent variations in markers of hypoxia (Hif1a), autophagy (Becn1) and neurogenesis (Sox2) highlighted neuroadaptive and cellular influences on ischemic resilience. Preconditioning enhanced synaptic plasticity by upregulating PSD-95, synaptophysin and BDNF levels. Additionally, preconditioning increased VEGF expression in blood serum reflecting vascular remodeling and neuroprotective angiogenesis. This study positions UCCAo induced CCH as a reliable model for exploring ischemic tolerance mechanisms to advance therapeutic strategies for mitigating the effects of ischemic stroke.
A Bibliometric Analysis of Online Education Research in India (2014-2024): Trends, Patterns, and Future Directions
Authors: Alrefaee Sara , Khan Mahlaqa , Alrefaee Yasser M. H. Ahmed 
Published: January 2025

Abstract

This study presents a comprehensive bibliometric analysis of online education research in India from 2014 to 2024, examining 1,396 Scopus-indexed publications to map the field's intellectual structure and evolution. Using advanced bibliometric techniques and visualization tools, we analyze publication patterns, institutional contributions, thematic developments, and international collaboration networks. The findings reveal significant growth in research output (11.94% annual growth rate) with a distinctive surge during 2020–2022, demonstrating both crisis response to the COVID-19 pandemic and sustained transformation in research priorities. Medical institutions emerge as unexpected research leaders, with the All India Institute of Medical Sciences contributing the highest number of publications (45). The analysis identifies three major research clusters: core educational technology (25% coverage), stakeholder focus (13%), and emerging technologies (6%). International collaboration patterns show moderate global engagement (15.69% co-authorship rate), with strong ties to Western institutions but limited South-South cooperation. Thematic analysis reveals evolution from basic implementation studies to sophisticated investigations of artificial intelligence and student-centered approaches. Citation analysis demonstrates high impact of pandemic-related research, with papers from 2020–2021 achieving exceptional citation rates. The study also identifies significant research gaps, particularly in rural and resource-constrained educational contexts. These findings provide valuable insights for researchers, policymakers, and practitioners while highlighting opportunities for future research directions in Indian online education.
Exceptional High-temperature Strength in an Additively Manufactured Al-based Superalloy with Stable Nanoscale Eutectic Cellular Network
Authors: Chen Zhe , Ma Siming , Fang Haixing , Ji Gang , Wang Mingliang , Cui Yuchi , Li Yang , Zhong Shengyi , Chen Han , Wu Yi , Zhou Ying , Nie Shixin , Lu Jian 
Published: January 2025

Abstract

Metallic materials typically experience significant strength degradation at elevated temperatures. Traditional strengthening methods, which rely on thermally stable particle dispersion, exhibit limited effectiveness owing to the challenges in suppressing thermally activated dislocation motion. This work introduces a novel strategy for achieving exceptional high-temperature strength through a thermally stable nanoscale eutectic cellular network (ECN) enabled by additive manufacturing. A near-eutectic AlLaScZr alloy is developed for laser powder bed fusion, incorporating an Al-La nanoscale ECN and dense intracellular nanoprecipitates. This alloy demonstrates excellent printability and remarkable high-temperature yield strength above 0.6Tm (~ 250 MPa at 300°C), outperforming conventional aluminium alloys by 2–5 times with minimal degradation after prolonged annealing. Compared with the conventional configuration of particle dispersion, the nanoscale ECN architecture enhances load-bearing capacity and strengthens aluminium by caging dislocation motion within ultrafine cells (~ 200 nm), effectively mitigating intrinsic high-temperature softening. The proposed transformative approach paves the way for designing next-generation heat-resistant alloys, unlocking new possibilities for additive manufacturing in high-temperature applications.
Research on Feature Scheduling Aggregation Clustering Model Based on Convolutional Neural Networks
Authors: Jiao Yu 
Published: January 2025

Abstract

This paper proposes a feature scheduling aggregation clustering model based on Convolutional Neural Networks (CNN), aiming to enhance the performance of clustering tasks using deep learning techniques. The model integrates the automatic feature extraction capability of CNN, the adaptive adjustment of feature scheduling, and the multi-band information integration of feature aggregation, thereby capturing the complex structures and subtle differences in data. Experimental results demonstrate the superiority of the model compared to existing algorithms and show good generalization ability. The model can effectively improve the effectiveness of cluster analysis, providing a new deep learning solution for data analysis.
Prolonged ICU Stay After Coronary Revascularization: Development and Validation of a Predictive Model
Authors: Agámez Diana Marcela Acosta , García Naiby Yulieth Liscano , Quintín María José Nieto , Rodríguez Brenda Yulieth González , Rodríguez Edith Elianna , Lima David Rene Rodriguez 
Published: January 2025

Abstract

Cardiac artery bypass grafting (CABG) is a common cardiac procedure with standardized postoperative intensive care unit (ICU) management. However, prolonged ICU stays increase complications, costs, and reduce service efficiency. We developed a prediction model for prolonged ICU stays in CABG patients based on a retrospective cohort. Prolonged ICU stay was defined as a stay of ≥ 7 days. Demographic data, laboratory results, and complications during the first 48 hours of ICU admission were analyzed. For the prediction model, variables with p < 0.25 in the univariate analysis were selected, followed by backward stepwise selection (significance level = 0.1). Interaction terms and fractional polynomials were evaluated, and bootstrapping was applied for external validation. Model performance was assessed using logistic regression diagnostics, ROC curve analysis (AUC), and calibration. The adjusted model equation was g(x) = age (0.0357) + left ventricular ejection fraction (LVEF) (-0.040) + perfusion time (0.0082) + hypothyroidism (0.754) + postoperative renal failure (1.653) + reoperation due to bleeding (1.885) + postoperative cerebrovascular event (1.287) + postoperative acute myocardial infarction (1.163) and the probability of in-hospital death was p (x) = e g (x)/(1 + e g (x)). The AUC of the ROC curve was 0.7671 (95% CI 0.7161 and 0.8066).
Development and Validation of MRI Radiomics Model for Predicting Perineural Invasion in Rectal Cancer
Authors: Cao Zhengyu , Yang Tiejun , Gong Wanfeng , Wang Jiahui , Fu Weiqi , Yang Dengfa , Guo Yuwen 
Published: January 2025

Abstract

Background
This study aims to explore the application of multiparametric MRI (mp-MRI) based radiomics in evaluating the perineural invasion (PNI) status of rectal cancer.
Methods
A retrospective analysis was conducted on clinical and MRI data from 423 rectal cancer patients confirmed by surgical pathology across two centers. A total of 343 patients from Center 1 were split into a training set and an internal validation (in-vad) set in an 8:2 ratio, while 80 patients from Center 2 served as an independent external validation (ex-vad) set. Univariate and multivariate analyses were performed on clinical features to construct a clinical model. Radiomic features were extracted using Pyradiomics software, and features were selected and reduced using mRMR and LASSO methods to construct the radiomics model. A combined model integrating clinical and radiomics features was subsequently built, and a nomogram was developed.
Results
Among all patients, 131 cases (31.0%) were PNI-positive. Multivariate analysis identified mrT (OR = 1.038, P < 0.001) and mrN (OR = 1.038, P < 0.001) as independent predictors of PNI, forming the clinical model. After radiomic feature selection, 30 features were used to build the radiomics model. The area under the curve (AUC) values for the clinical model in the training, in-vad, and ex-vad sets were 0.719, 0.631, and 0.760, respectively. The AUC values for the radiomics model were 0.841, 0.815, and 0.916, while those for the combined model were 0.899, 0.826, and 0.914. The Delong test demonstrated that both the radiomics and combined models outperformed the clinical model across all datasets, with no statistically significant difference between the radiomics and combined models.
Conclusions
The mp-MRI based radiomics model effectively predicts PNI status in rectal cancer, providing a non-invasive and accurate method for preoperative evaluation.
Neuroendoscopic Management for Right Epileptogenic Hypothalamic Hamartoma
Authors: Cavalheiro Sergio , Quiróz José Antonio Rangel , Dastoli Patricia Alessandra , Kim Isaque Hyung Tong , Suzuki Fernando Seiji , Costa Marcos Devanir Silva da 
Published: January 2025

Abstract

Hypothalamic hamartomas are congenital hypothalamus lesions that usually cause refractory seizures, endocrinological disturbances, cognitive decline, and psychiatric symptoms.
Magnetic resonance imaging of the brain with and without contrast agent is the gold standard for diagnosis.
Surgery is generally indicated when medication-refractory seizures occur.
We present the case of a 4-year-old boy with epilepsy refractory to anticonvulsant medications where magnetic resonance imaging revealed a lesion at the level of the right mammillary body.
We present endoscopic resection of the right hamartoma, which improved the patient’s seizures (Engel I) without neurological complications in his postoperative images and without complications in his postoperative images.
Differential Impact of Maternal and Paternal Metabolic Syndrome on Offspring’s Cardiometabolic Risk Factors
Authors: Park Jun-Hong , Cho Min Hyung , Shim Young Suk , Lee Hae Sang 
Published: January 2025

Abstract

This study compared the sex-specific influence of maternal and paternal metabolic syndrome on offspring using the 2007–2020 Korean National Health and Nutritional Examination Survey database. As a result, male offspring of fathers with metabolic syndrome presented increased blood glucose levels and unfavorable lipid profiles, whereas female offspring presented increased blood pressure, increased triglyceride levels, and decreased HDL cholesterol levels. Maternal metabolic syndrome was associated with adverse lipid profiles in offspring of both sexes, along with increased blood pressure in males and increased waist circumference and systolic blood pressure in females. When both parents had metabolic syndrome, the adjusted odds ratios for metabolic syndrome and most of its components were significantly elevated for male offspring. Conversely, female offspring exhibited relatively less elevated odds ratios of the metabolic syndrome. The disparate transgenerational impact on metabolic health by sexes emphasizes the need for sex-specific screening and management strategies for families with metabolic syndrome.