bluuebunny/crossref_metadata_2025_split huggingface dataset:
A literature review of the maxillary sinus with special emphasis on its anatomy and odontogenic diseases associated with it
Authors: Somayaji Krishnaraj , Muliya Vidya Saraswathi , KG Mohandas Rao , Malladi Ujwal Kumar , Nayak Satheesha B. 
Published: November 2023

AbstractMaxillary air sinus (MS) is the largest and clinically most important air sinus because of its anatomical relationship with the nasal cavity and especially with teeth of the upper jaw. Periapical dental infection frequently spreads to the maxillary sinus leading to its secondary infection. The occurrence of maxillary sinusitis due to the odontogenic causes is one of the common clinical conditions which is frequently encountered by the endodontists. While handling such cases, the gross anatomy and structure of MS are visualized using various radiological images. However, most of the time, it is challenging for dentists to understand the MS due to its complicated morphology. Keeping this in mind, this literature review is done to comprehensively compile the details on MS from anatomy, radiology, and endodontic importance point of view. The articles were selected from databases like PubMed, Scopus, Embase, and Google Scholar using the keywords “maxillary sinus,” “maxillary sinusitis,” “Endo antral syndrome,” “periapical surgery,” and “odontogenic infections.” In addition, a literature survey was also done using phrases like “roots extending into maxillary sinus,” “foreign bodies in maxillary sinus,” etc. Anatomical variation of sinus could be of clinical importance and the knowledge about the same could come in handy in treatment planning of upper teeth. Extruded materials from the root of a tooth into the sinus can make it prone to infection. The dentist should carefully evaluate the root of a tooth during root canal treatment.
Beyond the cold baths: contemporary applications of cold-water immersion in the treatment of clinical depression and anxiety
Authors: Carona Carlos , Marques Sandra 
Published: November 2023

SUMMARYCold-water immersion (e.g. adapted cold showers, partial or whole-body immersion, cold swimming) are nowadays increasingly being used as an adjunctive procedure to enhance the effects of primary treatment of various clinical conditions, including depressive and anxiety disorders. This brief article reviews the evidence regarding the beneficial effects of cold-water immersion on clinical depression and anxiety and outlines potential therapeutic mechanisms underlying the intervention. Promising avenues for future research and best practice recommendations are also discussed to improve the clinical effectiveness of cold-water immersion.
V-Learning—A Simple, Efficient, Decentralized Algorithm for Multiagent Reinforcement Learning
Authors: Jin Chi , Liu Qinghua , Wang Yuanhao , Yu Tiancheng 
Published: November 2023

A major challenge of multiagent reinforcement learning (MARL) is the curse of multiagents, where the size of the joint action space scales exponentially with the number of agents. This remains to be a bottleneck for designing efficient MARL algorithms, even in a basic scenario with finitely many states and actions. This paper resolves this challenge for the model of episodic Markov games. We design a new class of fully decentralized algorithms—V-learning, which provably learns Nash equilibria (in the two-player zero-sum setting), correlated equilibria, and coarse correlated equilibria (in the multiplayer general-sum setting) in a number of samples that only scales with [Formula: see text], where Ai is the number of actions for the ith player. This is in sharp contrast to the size of the joint action space, which is [Formula: see text]. V-learning (in its basic form) is a new class of single-agent reinforcement learning (RL) algorithms that convert any adversarial bandit algorithm with suitable regret guarantees into an RL algorithm. Similar to the classical Q-learning algorithm, it performs incremental updates to the value functions. Different from Q-learning, it only maintains the estimates of V-values instead of Q-values. This key difference allows V-learning to achieve the claimed guarantees in the MARL setting by simply letting all agents run V-learning independently. Funding: This work was partially supported by Office of Naval Research Grant N00014-22-1-2253.
A rare case of paraneoplastic Guillain-Barré syndrome in a patient with endometrial cancer
Authors: Farook Asif Mohamed , Priyankara Dilshan , Aluwihare Chamali , Mendis Anthony 
Published: November 2023

Introduction: Guillain-Barré syndrome is an acute, inflammatory polyradiculoneuropathy of autoimmune aetiology. It is a rare disease seen in 1 in 100,000 person-years. Up to 20% of those affected develop severe disability; mortality in Guillain-Barré syndrome is 5%. Guillain-Barré, associated with many malignancies as a paraneoplastic phenomenon, has been reported – especially in haematological malignancies such as lymphoma and leukaemia. Solid tumours associated with paraneoplastic Guillain-Barré syndrome are breast and lung cancers. The association between paraneoplastic Guillain-Barré syndrome and gynaecological malignancies are rare, and only a handful of cases have been previously reported in gynaecological cancers. Case description: We discuss a 65-year-old Sri Lankan female patient diagnosed with metastatic endometrial carcinoma who presented with paraneoplastic Guillain-Barré syndrome. The patient was treated appropriately and eventually recovered from her condition. Conclusion: Paraneoplastic Guillain-Barré syndrome is a rare phenomenon that clinicians can easily miss, and it has rarely been described in gynaecological cancers. Our patient was diagnosed with this rare phenomenon. The timely recognition and prompt treatment of this potentially life-threatening condition with multiple complications is essential in managing patients with malignancies and neuropathy. Further studies on paraneoplastic Guillain-Barré syndrome are needed as cases may be underreported.
Long-term tolerance and efficacy of siltuximab (anti-IL-6) in a young adult with idiopathic multicentric Castleman disease during COVID-19
Authors: Bedier Helbies , Isnard Stéphane , Maedler-Kron Chelsea , Routy Jean-Pierre 
Published: November 2023

Background: Castleman disease (CD) is a rare lymphoproliferative disorder with various subtypes, including the HHV-8-negative/idiopathic multicentric CD (iMCD). The diagnosis of iMCD remains challenging due to its non-specific presentation, in the form of generalised lymphadenopathies and inflammation. Two clinical presentations have been recently defined: a severe form iMCD-TAFRO and a milder form of iMCD not otherwise specified (iMCD-NOS). identification of interleukin-6 (IL-6) as a major culprit of inflammatory symptoms led to the development of anti-IL-6 therapies, with siltuximab being the approved first-line treatment. Case description: A 16-year-old male presented with recurrent fever, night sweats and several other non-specific symptoms. After extensive evaluations, an excisional lymph node biopsy confirmed the iMCD-NOS diagnosis. The patient received high-dose steroid therapy followed by siltuximab for four years. This treatment was well tolerated with only mild neutropenia not leading to dose adjustment. On siltuximab, the patient developed two mild COVID-19 episodes. His response to siltuximab remained effective throughout four years. Discussion: The absence of biomarker or causal agent identification poses a diagnostic challenge requiring lymph node histopathology for a definitive diagnosis of iMCD. Anti-IL 6 (siltuximab) is the recommended frontline therapy, suppressing inflammation and halting disease progression. Intravenous administration every 3 to 6 weeks can impact patient quality of life, prompting further research for alternative treatments. High-dose steroids, rituximab, cyclosporine, tacrolimus, lenalidomide or combined chemotherapy such as rituximab-bortezomib-dexamethasone are among the considered options according to disease severity. Conclusion: Overall, long-term siltuximab effectively controlled iMCD symptoms and was well tolerated by this young adult, who endured two mild COVID-19 episodes.
BORS/BJR TRAVELLING FELLOWSHIP: IMAGE-DRIVEN SUBJECT-SPECIFIC SPINE MODELS: DEVELOPING A NOVEL TOOL TO MEASURE IN VIVO LOADING
Authors: Williams David , Ward Michael , Kelly Emily , Shillabeer Dionne , Williams Jenny , Javadi Akbar , Holsgrove Timothy , Meakin Jude , Holt Cathy 
Published: November 2023

AbstractObjectivesSpinal disorders such as back pain incur a substantial societal and economic burden. Unfortunately, there is lack of understanding and treatment of these disorders are further impeded by the inability to assess spinal forces in vivo. The aim of this project is to address this challenge by developing and testing a novel image-driven approach that will assess the forces in an individual's spine in vivo by incorporating information acquired from multimodal imaging (magnetic resonance imaging (MRI) and biplane X-rays) in a subject-specific model.MethodsMagnetic resonance and biplane X-ray imaging are used to capture information about the anatomy, tissues, and motion of an individual's spine as they perform a range of everyday activities. This information is then utilised in a subject-specific computational model based on the finite element method to predict the forces in their spine. The project is also utilising novel machine learning algorithms and in vitro, six-axis mechanical testing on human, porcine and bovine samples to develop and test the modelling methods rigorously.Results & DiscussionMRI sequences have been identified that provide high-quality image data and information on different tissue types which will be used to predict subject-specific disc properties. In-vivo protocols to capture motion analysis, EMG muscle activity, and video X-rays of the spine have been designed with planned data collection of 15 healthy volunteers. Preliminary modelling work has evaluated potential machine learning approaches and quantified the sensitivity of the models developed to material properties.ConclusionThe development and testing of these image-driven subject-specific spine models will provide a new tool for determining forces in the spine. It will also provide new tools for measuring and modelling spine movement and quantifying the properties of the spinal tissues.AcknowledgmentsFunding from the EPSRC: EP/V036602/1 (Meakin, Holsgrove & Javadi) and EP/V032275/1 (Holt & Williams).Declaration of Interest(b) declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research reported:I declare that there is no conflict of interest that could be perceived as prejudicing the impartiality of the research project.
Design and implementation of a dual aspheric integrated shaping element for a high-power fiber laser
Authors: Xiong Yupeng , Chen Shiyu , Ma Yanxing , Ou Yang , Lu Wenwen , Dai Yifan , Chen Shanyong , Huang Cheng 
Published: November 2023

A dual aspheric integrated beam shaper suitable for a high-power laser situation has been designed and realized. The model for this lens was derived theoretically and the performance was evaluated using a detailed simulation. The ultrasonic vibration assisted cutting and the high-precision grinding and polishing technology were used for the processing. The surface accuracy was less than 200 nm measured with a profiler, and the roughness was smaller than 20 nm with the help of the white light interferometer. Shaping experiments were carried out, which verified that the Gaussian beam has uniform intensity distribution with a uniformity of 85.13% in the near field and converges to a point in the far field, which is exactly as expected. It thus provides an actual selection for high-power laser shaping.
Burden among informal caregivers of individuals with heart failure: A mixed methods study
Authors: Durante Angela , Younas Ahtisham , Cuoco Angela , Boyne Josiane , Rice Bridgette M. , Juarez-Vela Raul , Zeffiro Valentina , Vellone Ercole 
Published: November 2023

Aims
To develop a comprehensive understanding of caregiver burden and its predictors from a dyadic perspective.

Method
A convergent mixed methods design was used. This study was conducted in three European countries, Italy, Spain, and the Netherlands. A sample of 229 HF patients and caregivers was enrolled between February 2017 and December 2018 from the internal medicine ward, outpatient clinic, and private cardiologist medical office. In total, 184 dyads completed validated scales to measure burden, and 50 caregivers participated in semi-structured interviews to better understand the caregiver experience. The Care Dependency Scale, Montreal Cognitive Assessment, and SF-8 Health Survey were used for data collection. Multiple regression analysis was conducted to identify the predictors and qualitative content analysis was performed on qualitative data. The results were merged using joint displays.

Results
Caregiver burden was predicted by the patient’s worse cognitive impairment, lower physical quality of life, and a higher care dependency perceived by the caregivers. The qualitative and mixed analysis demonstrated that caregiver burden has a physical, emotional, and social nature.

Conclusions
Caregiver burden can affect the capability of informal caregivers to support and care for their relatives with heart failure. Developing and evaluating individual and community-based strategies to address caregiver burden and enhance their quality of life are warranted.
Punic my
c
ms and Greek Μαιουμα(ς): a re-examination
Authors: Schmitz Philip 
Published: November 2023

Abstract
My goal in this study is to persuade the reader that the word mycms is a compound noun with the elements /may/ + /yucmas/. I will endorse the analysis argued by Good that the Punic compound can be explained by reference to the Greek word Μαιουμα(ς), the name of a spring festival. To the cogent objections of critics of the seemingly odd compound implied by this analysis, I offer agreement, but also the further observation that linguistic theory predicts its oddness. Punic mycms provides an example of noun incorporation, a process of deriving lexemes from sentence elements.
New Excavations in the Sanctuary of Ba‘l Ḥammon in Carthage
Authors: Jerbania Imed Ben , Ferjaoui Ahmed , Peña Victoria , Redissi Taoufik , Jendoubi Kaouther , Maddahi Nesrine , Khalfalli Walid 
Published: November 2023

Abstract
Recent excavations, undertaken since 2014 at the sanctuary of Ba‘l Ḥammon in Carthage, have had as their objective the identification of various stratigraphic sequences that testify to changes in the spatial extension and chronological stratification of this precinct. The different categories of material artifacts, including urns and stelae, will be published with precisely dated archaeological contexts for the first time. Our stratigraphic controls will allow for a better understanding of how the sanctuary was used, including how various ritual gestures were carried out within the precinct.
Efficacy and safety of leuprorelin 3-month depot (11.25 mg) for idiopathic central precocious puberty treatment of Chinese girls: a single-center retrospective study
Authors: Huang Siqi , Zhang Lina , Gao Chenchen , Ou Hui , Hou Lele , Liu Zulin , Wang Dilong , Xu Yingying , Liang Liyang , Meng Zhe 
Published: November 2023

Abstract

Objectives
This study aimed to evaluate the efficacy and safety of 3-month leuprorelin acetate (3-month LA, 11.25 mg) for the treatment of idiopathic central precocious puberty (ICPP) in Chinese girls.

Methods
We conducted a single-center retrospective study in China on 28 girls with ICPP who received at least one year of 3-month LA treatment. Data from anthropometry, biochemistry, bone age (BA), and pelvic ultrasonography were assessed before and every 6 months during medication.

Results
At CPP diagnosis, the mean chronological age (CA) was 7.8±0.8 years, with bone age advancement (BA–CA) of 1.5±0.8 years. After treatment initiation, growth velocity decreased significantly from 8.5±1.6 cm/year to 5.8±1.1 cm/year at month 12 (p<0.001). GnRH-stimulated peak LH ≤3IU/L, the primary efficacy criterion, was observed in 27 out of 28 (96.4 %) children at month 3. Basal estradiol <20 pg/mL was achieved by all 28 girls (100 %) at month 6 and remained stable at month 12. Basal follicle-stimulating hormone (FSH) decreased from 4.1±3.5 to 1.7±0.9 (p<0.001), and basal LH was also significantly reduced from 3.3±6.5 to 0.7±0.8 (p=0.035) at month 12. The mean predicted adult height (PAH) at treatment initiation was 152.7±5.8 cm, it increased significantly to 157.5±5.5 cm (p=0.007) after one-year treatment. Pubertal development was slowed in most patients, and in some cases, it was even reversed. Only one patient (3.6 %) reported local intolerance.

Conclusions
Three-month leuprorelin acetate is a safe and effective treatment for suppressing the pituitary–gonadal axis and restoring impaired adult height in Chinese girls.
Timolaos oder Freundschaft. Philia und eironeia in Lukians Navigium
Authors: Kaiser Niklas 
Published: November 2023

Abstract
Traditionally, Lucian’s Navigium is regarded as a moralizing dialogue, which criticizes unrealistic aspirations. Lycinus incorporates this criticism by attacking his friends ironically. This essay elaborates that the dialogue also offers a more ethical interpretation that problematizes Lycinus’ moralizing attitude towards his friends. It argues that Timolaus, one of Lycinus’ interlocutors and friends, introduces a discourse about the reciprocal connection between the act of storytelling on the one hand, and friendship on the other. By doing so, aesthetics (stories) and ethics (friendship) appear as complementary. To emphasize this perspective on the dialogue, the modern concept of narrative communities is connected with ancient concepts of friendship. Lycinus’ ironizing voice and behavior can then be seen as antagonistic rather than dominant. Timolaus, however, appears as subtle narrator, who by his own wish tries to make Lycinus aware of the importance of storytelling for friendship.
Modestus at Edessa. Imperial officials in the ecclesiastical histories of Rufinus, Socrates, Sozomen, and Theodoret
Authors: Whelan Robin 
Published: November 2023

Abstract
This article considers the depictions of imperial officials and their interactions with Christian communities in the genre of ecclesiastical history. It focuses on one particular episode where the emperor Valens ordered his praetorian prefect Domitius Modestus to disperse an assembly of Nicene Christians at the martyrium of Thomas at Edessa. The four fifth-century Nicene ecclesiastical historians Rufinus, Socrates, Sozomen, and Theodoret offer the same basic narrative of the events which led to the prefect’s abandonment of his mission. Yet they construe the causes and implications of his reluctance to persecute in strikingly different ways. These adaptations reveal their differing views of the role of imperial officials in matters concerning the church and, more broadly, of what Christian communities might expect from the imperial state in a Christian empire.
Ein ungebildeter Bischof oder ein unterschätzter Gelehrter? Prämissen, Probleme und Perspektiven einer neuen Edition der Historien des Gregor von Tours
Authors: Schirner Rebekka 
Published: November 2023

Abstract
The Histories of Gregory of Tours are among the most important literary testimonies for the transition period from Late Antiquity to the early Middle Ages. The verdict on the Latin literature and language of the first centuries of the Frankish Empire has often been very negative. Krusch and Levison, who published today’s still authoritative critical edition of the Histories, also assumed that Gregory’s original text could only have been written in poor Merovingian Latin. This paper presents arguments for a new edition of the Histories from different perspectives. Gregory’s testimonies in which he addresses his own linguistic and grammatical deficiencies or the necessity of writing in a simple language, have to be viewed and evaluated within the larger tradition of statements of this kind in (Late) Antiquity. They should, thus, not be read as evidence for the argument that Gregory’s Histories were written in poor and incorrect Latin. An assumption of this kind, however, has influenced Krusch’s and Levison’s evaluation of the manuscripts of Gregory’s Histories and is thus reflected in their reconstructed text, even though quite a few manuscripts offer a much better text. This approach has repeatedly been criticised by different scholars; my paper joins this criticism. In assessing the various manuscripts of Gregory’s Histories, the editors have to make a decision regarding the presumed quality and state of Gregory’s Latin. My paper, therefore, also offers a case-study of Gregory’s stylistic and rhythmic arrangement of his text. The analysis of the so-called prose rhythm provides important evidence in favour of a positive assessment of Gregory’s level of education and thus of his linguistic and grammatical proficiency. This can also be viewed as an argument for a new and appropriate edition.
Efficient removal of U(VI) from aqueous solution by hydroxyapatite/graphene oxide composite microspheres
Authors: Wu Wenjun , Wang Jianlong 
Published: November 2023

Abstract
Effective treatment of uranium-containing wastewater is of great significance to the sustainable development of nuclear power and the protection of ecological environment. In this study, a highly efficient uranium adsorbent, graphene oxide (GO)/nano-hydroxyapatite (nHA) composite microspheres (nHA@rGO) was synthesized, which could effectively remove uranium from aqueous solution. Under the condition of pH = 3.5, T = 298 K, the maximum adsorption capacity reached 1672.96 mg/g. The results of batch experiments showed that the adsorption capacity of nHA@rGO microspheres was higher than that of nHA microspheres, indicating the enhancement of GO. The adsorption kinetics conformed to the pseudo second-order model. The changes of nHA@rGO microspheres before and after uranium adsorption were analyzed by FT-IR, XPS and XRD. The mechanisms of U(VI) ions adsorption onto nHA@rGO microspheres involved precipitation, surface complexation and ion exchange, in which the hydroxyl and phosphoric acid groups played important roles. The results showed that the prepared nHA@rGO microspheres can be used as an efficient and promising adsorbent for the treatment of uranium-containing wastewater.