bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical efficacy of stromal vascular fraction gel in the treatment of mature striae distensae
Authors: Li Meijia , Tian Yuan , Cheng Rong , Hao Lijun 
Published: January 2024

AbstractBackgroundStriae Distensae (SD) is a common dermatological lesion. The mechanism of formation is unclear, the prevailing theory is mechanical pulling of the skin and hormonal changes. Traditional SD treatment methods include topical drugs, photoelectric therapy, stripping and others, but each has limitations. Stromal vascular fraction gel (SVF‐gel) is a filler physically prepared from granular fat, enriched with adipose‐derived stem cells (ADSCs) and extracellular matrix (ECM). A good effect in the treatment of neck lines, wounds, acne, and other aspects. SD formation and treatment goals are comparable to those of neck lines. In this study, SVF‐gel filling will be used to treat mature SD, and its effectiveness and safety will be discussed in detail.MethodsFrom December 2019 to June 2022, recruit patients who want to treat SD caused by obesity or pregnancy among those who have “autologous fat aspiration” to change their body shape. Preoperatively, the area to be treated for SD was marked, autologous fat aspiration was performed, and the aspirated fat was prepared as SVF‐gel and filled into the preoperatively marked SD. All patients had preoperative and postoperative follow‐up with planar photographs and VISIA skin analyzer photographs to assess surgical results and safety from subjective and objective perspectives.ResultsA total of 36 patients were enrolled, with 31 of them successfully followed up on. The mean Global Aesthetic Improvement Scale (GAIS) score six months after surgery was 1.87 ± 0.03. At six months postoperatively, the overall patient satisfaction rate was 90%. The depth, area, and color of SD improved six months after surgery, and no serious complications occurred in any of the patients.ConclusionsSVF‐gel is a safe and effective method of improving mature SD and can be used as a clinical treatment option.
Cytomegalovirus related hospitalization costs among hematopoietic stem cell and solid organ transplant recipients treated with maribavir versus investigator‐assigned therapy: A US‐based study
Authors: Schultz Bob G. , Bullano Michael , Paratane Deepika , Rajagopalan Krithika 
Published: January 2024

AbstractBackgroundCytomegalovirus (CMV) infections among hematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT) recipients impose a significant health care resource utilization (HCRU)‐related economic burden. Maribavir (MBV), a novel anti‐viral therapy (AVT), approved by the United States Food and Drug Administration for post‐transplant CMV infections refractory (with/without resistance) to conventional AVTs has demonstrated lower hospital length of stay (LOS) versus investigator‐assigned therapy (IAT; valgancilovir, ganciclovir, foscarnet, or cidofovir) in a phase 3 trial (SOLSTICE). This study estimated the HCRU costs of MBV versus IAT.MethodsAn economic model was developed to estimate HCRU costs for patients treated with MBV or IAT. Mean per‐patient‐per‐year (PPPY) HCRU costs were calculated using (i) annualized mean hospital LOS in SOLSTICE, and (ii) CMV‐related direct costs from published literature. Probabilistic sensitivity analysis with Monte‐Carlo simulations assessed model robustness.ResultsOf 352 randomized patients receiving MBV (n = 235) or IAT (n = 117) for 8 weeks in SOLSTICE, 40% had HSCT and 60% had SOT. Mean overall PPPY HCRU costs of overall hospital‐LOS were $67,205 (95% confidence interval [CI]: $33,767, $231,275) versus $145,501 (95% CI: $62,064, $589,505) for MBV and IAT groups, respectively. Mean PPPY ICU and non‐ICU stay costs were: $32,231 (95% CI: $5,248, $184,524) versus $45,307 (95% CI: $3,957, $481,740) for MBV and IAT groups, and $82,237 (95% CI: $40,397, $156,945) MBV versus $228,329 (95% CI: $94,442, $517,476) for MBV and IAT groups, respectively. MBV demonstrated cost savings in over 99.99% of simulations.ConclusionsThis analysis suggests that Mean PPPY HCRU costs were 29%–64% lower with MBV versus other‐AVTs.
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Pattern and predictors of non‐adherence to diabetes self‐management recommendations among patients in peripheral district of Bangladesh
Authors: Banu Bilkis , Khan Md. Mobarak Hossain , Ali Liaquat , Barnighausen Till , Sauerborn Rainer , Souares Aurélia 
Published: January 2024

AbstractObjectivesThis study was designed to determine the extent of non‐adherence to the different dimensions of diabetes self‐management and to identify the factors influencing non‐adherence among peripheral patients in Bangladesh.MethodsA cross‐sectional study was conducted among 990 adult diabetic patients residing in Thakurgaon district, Bangladesh. Data were collected through face‐to‐face interviews including socio‐demographic information, disease and therapeutic, health services, knowledge and adherence to self‐management components.ResultsThe proportion of non‐adherence to drug prescription was 66.7%, dietary regimen (68.9%), physical exercise (58.0%), follow‐up visit/blood glucose test (88.2%), stopping tobacco (50.6%), and regular foot care (93.9%). Significant predictors for non‐adherence to drug were poorest socio‐economic status (OR = 2.47), absence of diabetic complications (OR = 1.43), using non‐clinical therapy (OR = 5.61), and moderate level of knowledge (OR = 1.87). Non‐adherence to dietary recommendations was higher for women (OR = 1.72), poorest socio‐economic status (OR = 3.17), and poor technical knowledge (OR = 4.68). Non‐adherence to physical exercise was lower for women (OR = 0.62), combined family (OR = 0.63), middle socio‐economic status (OR = 0.54), and moderate knowledge on physical exercise (OR = 0.55). Non‐adherence to follow‐up visits/blood glucose test was higher among patients who did not have diabetic complications (OR = 1.81) and with own transport (OR = 2.57), and respondents from high‐income group (OR = 0.23) were less likely to be non‐adherent. Non‐adherence to stopping tobacco was higher for older individuals (OR = 1.86); but lower for women (OR = 0.48), individuals with higher education level (OR = 0.17) and patients sick for a longer time (OR = 0.52). Non‐adherence to foot care was higher for patients who needed longer time to go to hospital (OR = 4.07) and had poor basic knowledge on diabetes (OR = 17.80).ConclusionAn alarmingly high proportion of diabetic patients did not adhere to diabetes self‐management. Major predictors for non‐adherence were related to patient's demographic characteristics and their experience with disease, treatment and health care services.
Riemann–Hilbert–Birkhoff inverse problem for semisimple flat F$F$‐manifolds and convergence of oriented associativity potentials
Authors: Cotti Giordano 
Published: January 2024

AbstractIn this paper, we address the problem of classification of quasi‐homogeneous formal power series providing solutions of the oriented associativity equations. Such a classification is performed by introducing a system of monodromy local moduli on the space of formal germs of homogeneous semisimple flat ‐manifolds. This system of local moduli is well defined on the complement of the strictly doubly resonant locus, namely, a locus of formal germs of flat ‐manifolds manifesting both coalescences of canonical coordinates at the origin, and resonances of their conformal dimensions. It is shown how the solutions of the oriented associativity equations can be reconstructed from the knowledge of the monodromy local moduli via a Riemann–Hilbert–Birkhoff boundary value problem. Furthermore, standing on results of B. Malgrange and C. Sabbah, it is proved that any formal homogeneous semisimple flat ‐manifold, which is not strictly doubly resonant, is actually convergent. Our semisimplicity criterion for convergence is also reformulated in terms of solutions of Losev–Manin commutativity equations, growth estimates of correlators of ‐cohomological field theories, and solutions of open Witten–Dijkgraaf–Verlinde–Verlinde equations.
The relationship between household food insecurity and overweight or obesity among children and adults in Canada: a population-based, propensity score weighting analysis
Authors: Fafard St-Germain Andrée-Anne , Hutchinson Joy , Tarasuk Valerie 
Published: January 2024

Household food insecurity is independently associated with adverse health outcomes among Canadians, but its association with overweight and obesity is poorly understood partly because of limited attention to confounding. This study assessed the relationship between food insecurity status and overweight/obesity in Canada. Cross-sectional data for individuals aged 2–64 years were drawn from the 2004 and 2015 Canadian Community Health Survey-Nutrition. Overweight/obesity was defined using body mass index calculated with measured height and weight. Food insecurity status was assessed with the 18-item Household Food Security Survey Module. The relationship was examined among preschool children ( n = 2007), girls ( n = 5512), boys ( n = 5507), women ( n = 8317), and men ( n = 7279) using propensity score weighted logistic regressions to control for confounding. Relative to their food-secure counterparts, girls in moderately food-insecure households (39.7% vs. 28.5%), boys in severely food-insecure households (54.4% vs. 35.0%), and women in moderately and severely food-insecure households (58.9% and 73.1% vs. 50.7%) had higher overweight/obesity prevalence; men in moderately food-insecure households had a lower prevalence (48.9% vs. 66.3%). With propensity score weighting, no association existed between food insecurity and overweight/obesity among preschool children, girls, boys, or men. For women, moderate (adjusted odds ratio (AOR): 1.61; 95% confidence interval (95%CI): 1.06–2.47) and severe (AOR: 2.33; 95%CI: 1.22–4.44) food insecurity was positively associated with overweight/obesity; the association was strongest for severe food insecurity and obesity (AOR: 3.38; 95%CI: 1.60–7.16). Additional research is needed to better understand the nature of the relationship among women. Problems of food insecurity and overweight/obesity among Canadian children and men should not be conflated in public health interventions.
Observational constraint in f(R, ∇R) gravity model in power-law cosmology
Authors: Dixit Archana 
Published: January 2024

In this paper, we have considered the flat Friedmann-Lemaître-Robertson-Walker (FRW) model in the framework of f( R, ∇ R) gravity. We have analyzed the significance of bulk viscosity in the f( R, ∇ R) gravity model to study the expansion of the universe. We have considered two bulk viscosity parameterizations and the use of power-law cosmology to constrain the model parameters H0 and q. Using the Bayesian analysis and likelihood function in conjunction with the Markov Chain Monte Carlo method, we obtained the model parameters [Formula: see text] and [Formula: see text]. The behaviors of energy density, bulk viscous pressure, and the effective equation of the state parameter with redshift are investigated in detail. These features demonstrate that the bulk viscosity is a valid candidate for acquiring the negative pressure needed to effectively drive the expansion of the universe. To check the validity of the f( R, ∇ R) model, we also analyze the behavior of energy conditions. The adiabatic squared speed of the sound is used to test the model’s stability. The Om( z) diagnostic is used in the model to identify the quintessence and phantom regions.
Structural control of igneous intrusions on fluid migration in sedimentary basins: the case study of large bitumen seeps at Cerro Alquitrán and Cerro La Paloma, northern Neuquén Basin, Argentina
Authors: Galland Olivier , Villar Héctor J. , Mescua José , Jerram Dougal A. , Messager Grégoire , Medialdea Adrian , Midtkandal Ivar , Palma J. Octavio , Planke Sverre , Augland Lars Eivind , Zanella Alain 
Published: January 2024

Abstract
Cooling subvolcanic igneous intrusions are known to have a tremendous impact on fluid flow in the shallow Earth's crust. However, the long-term post-cooling legacy of subvolcanic intrusions on fluid flow has received much less attention. Here we describe geological examples in the Andean foothills, Argentina, showing that igneous intrusions have long-term effects on fluid flow after their emplacement and cooling. The case study consists of ∼11 Myr-old eroded andesitic intrusions of Cerro Alquitrán and Cerro La Paloma, northern Neuquén Basin, Argentina, at the rims of which large volumes of bitumen are naturally seeping out at the Earth's surface. The intrusions exhibit laccolithic shapes with steep-sided contacts with the host rock. Near the intrusive contacts, the andesite is intensely broken along concentric breccia bands and fracture bands, interpreted as resulting from syn-emplacement brittle magma deformation, which represent high-permeability pathways for the migrating bitumen. Organic geochemical analyses of the bitumen show that the seeping oils were generated from incipiently mature Vaca Muerta sections located in a regional kitchen to the west, implying a lateral migration of ∼10–20 km. The Cerro Alquitrán and Cerro La Paloma intrusions are demonstrative examples highlighting how extinct subvolcanic intrusions have long-term consequences for subsurface fluid circulations in sedimentary basins.
Next-generation Multi-target Stool DNA Panel Accurately Detects Colorectal Cancer and Advanced Precancerous Lesions
Authors: Gagrat Zubin D. , Krockenberger Martin , Bhattacharya Abhik , Gagrat Bridget Z. , Leduc Christine M. , Matter Michael B. , Fourrier Keith D. , Mahoney Douglas W. , Edwards V David K. , Lidgard Graham P. , Limburg Paul J. , Johnson Scott C. , Domanico Michael J. , Kisiel John B. 
Published: January 2024

Abstract

The multi-target stool DNA (mt-sDNA) test screens for colorectal cancer by analyzing DNA methylation/mutation and hemoglobin markers to algorithmically derive a qualitative result. A new panel of highly discriminant candidate methylated DNA markers (MDM) was recently developed. Performance of the novel MDM panel, with hemoglobin, was evaluated in a simulated screening population using archived stool samples weighted to early-stage colorectal cancer and prospectively collected advanced precancerous lesions (APL). Marker selection study (MSS) and separate preliminary independent verification studies (VS) were conducted utilizing samples from multi-center, case–control studies. Sample processing included targeted MDM capture, bisulfite conversion, and MDM quantitation. Fecal hemoglobin was quantified using ELISA. Samples were stratified into 75%/25% training-testing sets; model outcomes were cross-validated 1,000 times. All laboratory operators were blinded. The MSS included 232 cases (120 colorectal cancer/112 APLs) and 490 controls. The VS featured 210 cases (112 colorectal cancer/98 APLs) and 567 controls; APLs were 86.7% adenomas and 13.3% sessile serrated lesions (SSL). Average age was 65.5 (cases) and 63.2 (controls) years. Mean sensitivity in the VS from cross-validation was 95.2% for colorectal cancer and 57.2% for APLs, with specificities of 89.8% (no CRC/APLs) and 92.4% (no neoplasia). Subgroup analyses showed colorectal cancer sensitivities of 93.4% (stage I) and 94.2% (stage II). APL sensitivity was 82.9% for high-grade dysplasia, 73.4% for villous lesions, 49.8% for tubular lesions, and 30.2% for SSLs. These data support high sensitivity and specificity for a next-generation mt-sDNA test panel. Further evaluation of assay performance will be characterized in a prospective, multi-center clinical validation study (NCT04144738).

Prevention Relevance:
This study highlights performance of the next-generation mt-sDNA test, which exhibits high sensitivity and specificity for detecting colorectal cancer and APLs. This noninvasive option has potential to increase screening participation and clinical outcomes. A multi-center, clinical validation trial is underway.
See related commentary by Bresalier, p. 93
Observing Mythical Entities
Authors: Altobrando Andrea 
Published: January 2024

Abstract
Sellars has taught us that we do not have direct epistemic access to sense data. Therefore, the latter cannot work as the bedrock of our knowledge. At the same time, through the myth of genius Jones, Sellars has tried to explain how we become able to rationally refer to sense data. What is more, it even seems that, following Jones’ teachings, the Rylean folk have become able to observe sense data. How could this be possible if sense data are merely mythical entities? By making use of some ideas and reflections from Husserl on perceptual experience, categorial intuition, and knowledge, I suggest a way to overcome the riddle. My solution, however, will partially contrast with Sellars’ idea that sense data are, in the end, something internal to the subject.
Was Moore Talking Nonsense?
Authors: Sartore Edoardo 
Published: January 2024

Abstract
This article examines Wittgenstein’s criticism of Moore’s use of “know”, as he developed it in On Certainty. Arguing against much of the literature, the author claims that, by Wittgenstein’s own lights, Moore was not talking nonsense. He does so by showing, first, that the standard reading is based on the idea that hinge propositions are non-epistemic, and second, that Wittgenstein’s alleged adoption of the non-epistemic view is not adequately supported by the textual evidence. The author argues that claims to the contrary depend on an undue conflation, on the part of interpreters, of Wittgenstein’s treatment of psychological avowals in Philosophical Investigations and his discussion of hinge propositions in On Certainty. Moreover, a closer look at Wittgenstein’s objections to Moore shows that Wittgenstein himself repeatedly charged Moore with a similar confusion between the status of psychological statements and the status of his common-sense truisms.
The Development of Arin kul ‘water’ ~ Kott ûl, Ket ¹u·l’, Yugh ¹ur and Its Typological Background
Authors: Fries Simon , Bonmann Svenja 
Published: January 2024

Abstract
This article seeks to demonstrate that prothetic k- in Arin corresponding to a zero onset in the other Yeniseian languages as featured in words like Arin kul ‘water’ ~ Kott ûl, Ket ¹u·l’, Yugh ¹ur reflects a Proto-Yeniseian word-initial consonant *u̯- [w]. Drawing on earlier findings concerning the development of Arin k-, it is argued that Proto-Yeniseian *u̯- developed into Arin k- via an intermediate stage *g(u̯)-, and that *u̯- was partly or completely lost in the other Yeniseian languages. Both the development *u̯- > *g(u̯)- > k- and the loss of *u̯- are backed up by typological evidence.
On Dagur Kinship Terms
Authors: Khabtagaeva Bayarma 
Published: January 2024

AbstractAccording to conventional linguistic classifications, Dagur is one of the archaic Mongolic languages. This language is unique, allegedly connected with the Para- Mongolic language Khitan, and it has a close areal relationship with two Tungusic languages, Manchu and Solon Ewenki. This paper is a continuation of the author’s research on etymological studies of the Dagur language. Two papers have already been published, focusing respectively on names for body parts (Khabtagaeva 2021) and colours (Khabtagaeva 2022). The present paper addresses kinship terminology. The Dagur terms were collected from different published works and fieldwork materials. Most of the terms are of Mongolic origin with special Dagur phonetic features and with an internal Dagur mophological development. A few terms were borrowed from Tungusic languages and Chinese.
Typological Reflections on the Rise of Possessive Alienability Splits in Tungusic
Authors: Malchukov Andrej L. 
Published: January 2024

Abstract
In this brief discussion note I consider rise of (in)alienability splits in Tungusic languages in a typological perspective. I provide typological arguments for the diachronic scenario (originally due to Sunik 1947), in which the interrogative pronoun ƞüi ‘who’ developed nominalizing and deictic function, subsequently giving rise to free possessive construction, on the one hand, and the alienability marker, on the other hand. It is shown that the proposed, typologically informed scenario can successfully account for peculiarities of the inalienable possession and related possessive markers in Tungusic languages, which alternative scenarios are not able to explain.
Proto-Nivkh Accent System
Authors: Zhivlov Mikhail 
Published: January 2024

Abstract
The aim of this paper is to reconstruct the Proto-Nivkh accent system and vocalism with the help of loanword analysis and internal reconstruction. It is shown that the place of the Proto-Nivkh accent depended on vowel height and syllable structure. The paper also argues that the unstressed vowel loss, which led to a radical change in Nivkh phonotactics, consonant system and morphophonology, occurred after the breakup of the last common ancestor of modern Nivkh varieties.
The Evolution of China’s Policy for Transitions from ecec to Primary Education and Its Characteristics: a Policy Review Based on Incrementalism Theory
Authors: Zhang Yulong , Hou Yuna , Lei Jiayu , Luo Xiaochen 
Published: January 2024

Abstract
Transitions from early childhood education and care (ecec) to primary education are not only about the quality of children’s early learning but also affect the development of children and are of great value in promoting the construction of high-quality education systems in various countries. This study uses incrementalism theory to review the policy content for transitions from ecec to primary education in China and finds that the policy has evolved through four stages: the gestation period, the initial exploration period, the steady development period, and the system construction period. The evolution of the policy has shown a characteristic step-by-step increase from small to large, seeking changes while maintaining stability. Through the review of China’s policy content for transitions from ecec to primary education, we hope to provide evidence from the Chinese experience to international research in related fields.
Eddy–Internal Wave Interactions and Their Contribution to Cross-Scale Energy Fluxes: A Case Study in the California Current
Authors: Delpech Audrey , Barkan Roy , Srinivasan Kaushik , McWilliams James C. , Arbic Brian K. , Siyanbola Oladeji Q. , Buijsman Maarten C. 
Published: January 2024

Abstract
Oceanic mixing, mostly driven by the breaking of internal waves at small scales in the ocean interior, is of major importance for ocean circulation and the ocean response to future climate scenarios. Understanding how internal waves transfer their energy to smaller scales from their generation to their dissipation is therefore an important step for improving the representation of ocean mixing in climate models. In this study, the processes leading to cross-scale energy fluxes in the internal wave field are quantified using an original decomposition approach in a realistic numerical simulation of the California Current. We quantify the relative contribution of eddy–internal wave interactions and wave–wave interactions to these fluxes and show that eddy–internal wave interactions are more efficient than wave–wave interactions in the formation of the internal wave continuum spectrum. Carrying out twin numerical simulations, where we successively activate or deactivate one of the main internal wave forcing, we also show that eddy–near-inertial internal wave interactions are more efficient in the cross-scale energy transfer than eddy–tidal internal wave interactions. This results in the dissipation being dominated by the near-inertial internal waves over tidal internal waves. A companion study focuses on the role of stimulated cascade on the energy and enstrophy fluxes.