bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hemolytic disease of the fetus and newborn due to minor blood group alloimmunization in a mother of sickle cell disease with multiple alloantibodies
Authors: Varghese Stephy , Prakash Satya , Mukherjee Somnath , Sahu Ansuman , Mishra Debasish 
Published: January 2024

Abstract
Hemolytic disease of the fetus and newborn is due to maternal IgG antibodies that transport through the placenta and destroy neonatal red cells. A mismatch of antigens between mother and fetus causes isoimmunization resulting in mild anemia, which may progress to fetal hydrops in the intrauterine period and severe hyperbilirubinemia to kernicterus in neonates. The isoimmunization is mainly caused by Rh-D and ABO antibodies. In this case report, we found neonatal hyperbilirubinemia due to the presence of anti-c alloantibody previously developed in a sickle cell disease (SCD) pregnant female. It is an unusual case of fetal hyperbilirubinemia due to minor blood group alloimmunization in a SCD needing exchange transfusion. Multi-transfused patients should be counseled regarding the need to perform antibody screening frequently before pregnancy for better treatment of both mother and child.
Quality assessment of platelet concentrates prepared by platelet-rich plasma, buffy-coat, and apheresis methods in a tertiary care hospital in South India: A cross-sectional study
Authors: Toora Esha , Kulkarni Rajendra G. , Manivannan Prabhu , Sastry Apurba Sankar , Basavarajegowda Abhishekh , Sahoo Dibyajyoti 
Published: January 2024

Abstract

INTRODUCTION:
In blood banking and transfusion medicine, it is of paramount importance to improve transfusion safety and provide a higher quality of product to maximize the therapeutic outcomes and minimize the risk of developing transfusion-associated complications for patients receiving a blood transfusion.

MATERIALS AND METHODS:
This was a cross-sectional study conducted at the department of transfusion medicine in a tertiary care hospital of South India from February 2019 to December 2020. The primary objective of the study was to assess the quality of platelet concentrates (PC) prepared by platelet-rich plasma (PRP), buffy-coat (BC), and apheresis method. A total of 760 PCs were subjected to quality assessment, among which 124 were PRP-PC, 176 were BC-PC, and 460 were single donor platelet (SDP).

RESULTS:
The total percentage of platelets meeting all the six quality control parameters in PRP, BC and SDP was 78.23%, 81.81%, and 89.96%, respectively. Apheresis PCs showed a significantly higher platelet concentration per µL on comparison with whole-blood-derived platelets. BC-PCs were found to be better than PRP-PC with regard to lower white blood cell (WBC) contamination (P < 0.05) and red blood cell (RBC) contamination (P < 0.01). No statistically significant difference was found with regard to platelet yield, volume, swirling, and pH.

CONCLUSION:

Ex vivo quality of PCs prepared by BC-PC, PRP-PC, and apheresis-PC fulfilled the desired quality control parameters. BC-PC was better than PRP-PC in terms of lesser WBC and RBC contamination and comparable in terms of volume, platelet yield, swirling, and pH. Apheresis PCs showed a higher platelet concentration per microliter on comparison with whole-blood-derived platelets; hence in a blood center where facilities for collection of apheresis product are available, SDPs should be the choice of platelet transfusion.
The effect of a barley-based food product in alleviating knee osteoarthritis discomfort symptoms in Egyptian female patients
Authors: Fouad Suzanne , Monir Rasha , Ibrahim Fatma A. , Hussein Ahmed M.S. , Shafei Heba F. , El Gendy Aliaa 
Published: January 2024

Background/aim
Osteoarthritis is a common joint condition that causes cartilage to erode. There are numerous conventional treatments available, including nonsteroidal anti-inflammatory medicines and pharmaceuticals containing glucosamine; however, taking them can result in serious side effects. The aim of this study was to prepare barley-based food product enriched with ginger, curcumin, garlic powder, and onion powder and to evaluate the effect of consumption of the prepared macaroni for 2 months, in alleviating knee osteoarthritis discomfort symptoms in female patients complaining of grade 2–3 knee osteoarthritis.

Patients and methods
The present study enrolled 51 Egyptian middle age females patients with a mean age of 51±8.37 years, diagnosed with bilateral grade two to three knee osteoarthritis were recruited from the National Research Centre rheumatology and rehabilitation clinic. Anthropometric measurements and blood samples were collected after 8 weeks of daily barley based macaroni supplementation (75 grams raw). Serum levels of IL1β, IL4 and IL6 were measured using Elisa techniques, while Total Antioxidant Capacity, Malondialdehyde, and Glutathione S-transferase were measured by the colorimetric methods.

Results
Chemical composition analysis of the prepared barley-based macaroni demonstrated a decrease in total carbohydrate content and an increase in crude fiber, protein, and fat content compared with the control (semolina wheat-based macaroni); 100 grams of the prepared uncooked barley macaroni provided 342.46 Kcal. The reevaluation of the anthropometric parameters after 8 weeks of daily macaroni supplementation denoting improvement without statistical significance (P>0.05), and the clinical characteristics of knee joint osteoarthritis (Lequesne Index, WOMAC score, and Timed Up and Go test) significantly improved which meant less pain and stiffness. The serum pro-inflammatory cytokines IL1β and IL6 declined significantly and the serum anti-inflammatory cytokine IL4 raised significantly (P≤0.05), besides, barley based macaroni supplementation significantly improved the antioxidant status, which was achieved through the rise of serum Total Antioxidant Capacity and the decline of Malondialdehyde and Glutathione S-transferase activity (P≤0.05).

Conclusion
Barley-based prepared macaroni enriched with curcumin and ginger must be considered in alleviating the severity of knee OA symptoms to aid patients in getting their life back to near normal.
Comparison of Three Methods to Extract Plasmodium falciparum DNA from Whole Blood and Dried Blood Spots
Authors: Thongseesuksai Thaksaporn , Boonmars Thidarut , Laummaunwai Porntip 
Published: January 2024

ABSTRACT.
This study aimed to compare the effectiveness of three DNA extraction methods: the GF-1 Blood DNA Extraction Kit (GF-1 BD Kit), which employs a spin column along with lysing and washing buffers; the tris-ethylenediaminetetraacetic acid and proteinase K (TE-pK) method, which utilizes a combination of TE buffer and proteinase K for cell lysis; and DNAzol® Direct (DN 131), a single reagent combined with heating for the extraction process. Plasmodium falciparum DNA was extracted from both whole blood and dried blook spots (DBSs), with consideration of DNA concentration, purity, cost, time requirement, and limit of parasite detection (LOD) for each method. The target gene in this study was 18S rRNA, resulting in a 395-bp product using specific primers. In the comparative analysis, the DN 131 method yielded significantly higher DNA quantities from whole blood and DBSs than the GF-1 BD Kit and TE-pK methods. In addition, the DNA purity obtained from whole blood and DBSs using the GF-1 BD Kit significantly exceeded that obtained using the TE-pK and DN 131 methods. For LOD, the whole blood extracted using the DN 131, GF-1 BD Kit, and TE-pK methods revealed 0.012, 0.012, and 1.6 parasites/µL, respectively. In the case of DBSs, the LODs for the DN 131, GF-1 BD Kit, and TE-pK methods were 1.6, 8, and 200 parasites/µL, respectively. The results revealed that the TE-pK method was the most cost-effective, whereas the DN 131 method showed the simplest protocol. These findings offer alternative approaches for extracting Plasmodium DNA that are particularly well-suited for large-scale studies conducted in resource-limited settings.
Gut Microbiome Diversity and Antimicrobial Resistance After a Single Dose of Oral Azithromycin in Children: A Randomized Placebo-Controlled Trial
Authors: Doan Thuy , Liu Zijun , Sié Ali , Dah Clarisse , Bountogo Mamadou , Ouattara Mamadou , Coulibaly Boubacar , Kiemde Dramane , Zonou Guillaume , Nebie Eric , Brogdon Jessica , Lebas Elodie , Hinterwirth Armin , Zhong Lina , Chen Cindi , Zhou Zhaoxia , Porco Travis , Arnold Benjamin F. , Oldenburg Catherine E. , Lietman Thomas M. 
Published: January 2024

ABSTRACT.
Mass antibiotic distribution to preschool children resulted in alterations of the gut microbiome months after distribution. This individually randomized, placebo-controlled trial evaluated changes in the gut microbiome and resistome in children aged 8 days to 59 months after one dose of oral azithromycin in Burkina Faso. A total of 450 children were randomized in a 1:1 ratio to either placebo or azithromycin. Rectal samples were collected at baseline, 2 weeks, and 6 months after randomization and subjected to DNA deep sequencing. Gut microbiome diversity and normalized antimicrobial resistance determinants for different antibiotic classes were evaluated. Azithromycin decreased gut bacterial diversity (Shannon P < 0.0001; inverse Simpson P < 0.001) 2 weeks after treatment relative to placebo. Concurrently, the normalized abundance of macrolide resistance genetic determinants was 243-fold higher (95% CI: 76-fold to 776-fold, P < 0.0001). These alterations did not persist at 6 months, suggesting that disruptions were transient. Furthermore, we were unable to detect resistance changes in other antibiotic classes, indicating that co-resistance with a single course of azithromycin when treated at the individual level was unlikely.
EVALUACIÓN DEL POTENCIAL FOTOVOLTAICO EN TEJADOS EN EL CANTÓN QUITO
Authors: Tapia Mariela , Ramos Leonard , Heinemann Detlev , Zondervans Edwin 
Published: January 2024

Este trabajo tiene por objetivo evaluar el potencial técnico y económico de la energía solar fotovoltaica en tejados de las parroquias urbanas y rurales del cantón Quito en Ecuador. Para esto, primero se calculó el área disponible de tejados y terrazas usando datos de sistema de información geográfica. Posteriormente, se calculó la energía fotovoltaica que podría ser generada utilizando una herramienta de modelado en Python. Por último, se evaluó la factibilidad económica en términos del costo nivelado de electricidad (LCOE - por sus siglas en inglés) bajo tres escenarios financieros. Los resultados indican que existe una superficie total disponible de 61 km² en la que podría instalarse una capacidad total de 5403.74 MWp y generar un total de 7851.51 GWh al año, lo cual podría cubrir 2.3 veces el consumo de electricidad registrado en 2019 en el cantón. Sin embargo, la evaluación económica revela que esta tecnología es competitiva únicamente en el escenario financiero bajo. Por lo tanto, estos resultados pueden apoyar a las autoridades locales en la planificación y diseño de políticas y estrategias financieras para incrementar la penetración de sistemas fotovoltaicos en tejados y así explotar el gran potencial fotovoltaico evaluado en el cantón Quito.
The Applications of Nanotechnology in Renewable Energy
Authors: Mose Patrick 
Published: January 2024

Purpose: The main objective of this study was to explore the applications of nanotechnology in renewable energy.
Methodology: The study adopted a desktop research methodology. Desk research refers to secondary data or that which can be collected without fieldwork. Desk research is basically involved in collecting data from existing resources hence it is often considered a low cost technique as compared to field research, as the main cost is involved in executive’s time, telephone charges and directories. Thus, the study relied on already published studies, reports and statistics. This secondary data was easily accessed through the online journals and library.
Findings: The findings revealed that there exists a contextual and methodological gap relating to the applications of nanotechnology in renewable energy. Preliminary empirical review revealed that the transformative potential of nanotechnology in revolutionizing renewable energy production, storage, and utilization. Through interdisciplinary collaboration and innovation, nanotechnology offers solutions to enhance the efficiency of photovoltaic cells, improve the performance of batteries and supercapacitors, and facilitate cleaner energy production with nanocatalysts. These findings underscore the need for continued research and development, paving the way for a more sustainable and environmentally friendly future in the renewable energy sector.
Unique Contribution to Theory, Practice and Policy: The Diffusion of Innovations Theory, Technology Acceptance Model (TAM) and Resource-Based View (RBV) Theory may be used to anchor future studies on nanotechnology and renewable energy. The study offered several key recommendations. Firstly, it emphasizes the importance of fostering collaborative research initiatives among academia, industry, and government agencies to accelerate the development and adoption of nanotechnology in renewable energy. Secondly, the study suggests investing in nanotechnology education and training programs to bridge the skills gap and equip the workforce with the necessary expertise. Lastly, it underscores the need for clear and comprehensive policy frameworks to regulate nanotechnology in the renewable energy sector, addressing safety, environmental, and ethical concerns while incentivizing compliance. These recommendations collectively aim to promote the responsible and efficient integration of nanotechnology in renewable energy, contributing to a sustainable and innovative energy landscape.
Predicting Microbiologically Influenced Concrete Corrosion in Self-Cleansing Sewers Using Meta-Learning Techniques
Authors: Zounemat-Kermani Mohammad , Aldallal Ammar 
Published: January 2024

Sewer networks are not only necessary as an infrastructure for human societies, but they can also help humans achieve a stable situation with the surrounding natural environment by controlling and preventing the spread of pollution in the environment. As a result, concrete sewer maintenance and analysis of their damaging elements are critical. In this regard, modeling microbiologically influenced corrosion (MIC) is a challenging phenomenon. Due to the complicated aspects related to the interaction of microorganisms and concrete degradation, this research suggests several machine-learning models as well as traditional multiple linear regression model to predict the MIC in sewer pipelines. The models can be categorized into three sections: (i) stand-alone models (group method of data handling, generalized regression neural network, radial basis function neural network, multilayer perceptron neural network, chi-square automatic interaction detection, and classification and regression tree); (ii) integrative models (adaptive neuro-fuzzy inference system and support vector regression with particle swarm optimization, artificial bee colony, and firefly algorithm); and (iii) ensemble meta-learner stepwise regression (SR) model. After implementing the models, statistical measures, including root mean square error, mean absolute error, mean bias error, Pearson correlation coefficient, and Nash-Sutcliffe model efficiency are considered for evaluating models’ performances. The results indicate that the ensemble meta-learner-SR model is significantly more precise than other models. They also demonstrate that using an integrative model can improve the accuracy of stand-alone models by at least up to 42%. The durability and lifespan of the sewer system are also estimated with the aid of the best predictive model (meta-learner-SR) for two scenario cases of (i) gas phase and (ii) submerged conditions. It is concluded that the sewer systems have a considerably lower life span (24 y less) exposed to submerged sewage than the gas phase with 56 y of durability.
Peace and Values Education as a Cross-Cutting Issue in Rwandan Schools: Teachers and Classroom-Based Perspective
Authors: Buhigiro Jean Leonard , Sibomana Emmanuel , Ngabonziza Jean de Dieu Amini , Mukingambeho Delphine , Ntawiha Philothere 
Published: January 2024

Peace and values is one of the cross-cutting issues in the Rwandan primary and secondary school curriculum. Different organizations such as the Aegis Trust have trained teachers in integrating peace and values in the various subjects, they teach by training learners on how to build a culture of peace. This is very important to Rwanda as a post genocide. However, no research (at the best of our knowledge) has been conducted to investigate how and to what extent teachers integrate peace and values in various school subjects. This article reports on empirical research conducted in five primary schools in four provinces of Rwanda plus Kigali City to examine the teaching of peace and values in Rwandan schools. A qualitative approach was adopted for this research. Classroom observations, focus group discussions and semi-structured interviews were conducted to collect data. Thematic content analysis was used to analyse the data. The findings show that peace values are not part of teachers’ planning and are not explicitly referred to in classroom practices. This is mainly because teachers lack skills and knowledge to do so. However, some peace related messages are shared in extracurricular activities but these are counteracted by violent practices such as corporal punishment and bullying. This article concludes that teachers’ limited understanding of peace impedes the integration of peace culture in schools. Thus, it suggests that peace values should be explicitly and systematically integrated in the teaching of all subjects. It also calls for strong measures to end school violence in Rwandan schools by equipping teachers for positive management of learners’ behaviours.
Intensive agricultural management-induced subsurface accumulation of water-extractable colloidal P in a Vertisol
Authors: Li Shouhao , Chen Shuiqing , Bai Shanshan , Tan Jinfang , Jiang Xiaoqian 
Published: January 2024

Abstract. Long-term excessive application of mineral fertilizer leads to phosphorus (P) accumulation, increasing the risk of P migration and loss from the soil profile. The colloids in the soil profile are important carriers for P migration due to their high P adsorption and transport capacity. It is not clearly understood how colloidal P (CP) is distributed in subsoils (<1.2 m) of a Vertisol, contributing to subsurface P loss. Understanding the depth sequence distribution and speciation of colloidal P in the soil profile is critical for a comprehensive assessment of P loss. In this study, water-extractable colloids (WECs) with the size of 0.35–2 µm were obtained from a 0–120 cm soil profile by a sedimentation and centrifugation scheme. The dissolved reactive P (DRP) and dissolved total P (DTP) in soil supernatant with particle sizes <0.35 µm were measured by molybdate blue colorimetry. Solution 31P nuclear magnetic resonance (NMR) and P K-edge XANES (X-ray absorption near-edge structure) were used to characterize the species and distribution of CP in the soil profile of fertilized farmland. Total and available P in bulk soil and colloids decreased with soil depth. The organic P (OP) contained 97–344 mg kg−1 per bulk soil and 110–630 mg kg−1 per WEC. The OP in soil profile consists of orthophosphate mono-esters and diesters primarily according to NMR results. It suggested that OP in WECs from subsoils might be affected by the translocation of CP from surface soils, probably due to soil acidification and preferential flow caused by swelling–shrinkage clays, including montmorillonite and nontronite detected by X-ray powder diffractometer (XRD) results. Additionally, the more negative zeta potential of surface soil colloids suggests the high mobility of colloidal P towards the subsoils. The CP concentration for <2 µm was about 38–93 mg P kg−1 per bulk soil, which is 6–37 times that of DRP, suggesting that CP plays a dominant role in P transport within the soil profile. The relatively small fraction of orthophosphate diesters suggests limited P assimilation by microorganisms for the accumulation of WECs containing organically bound P in subsoils. The P K-edge XANES results indicated that the proportions of Al-P, Fe-P, and inositol hexakisphosphate (IHP) of WECs decreased, but hydroxyapatite (HAP) increased with soil depth. This study showed that inorganic and organic P migrated from the surface to deeper layers along the soil profile, with soil colloids having a significant effect on P migration from both surface and subsurface layers. The findings have an important significance for soil P migration evaluation and agricultural non-point source pollution control in Vertisols.
Innovative Modular Approach to High Concentration CSP Systems. Results and Achievements From the First-of-its-Kind 300 kWt Semi-Fresnel Fixed Mirror Module Prototype Up and Running
Authors: Peña Adrián , Villasante Cristóbal , Ramirez David , Herrador Miguel , Pereira Daniel , Barat Yannick , Ubach Josep , Saur Mirko , Pagola Íñigo , Sánchez Marcelino , Bernardos Ana , Olasolo David , Herrero Saioa 
Published: January 2024

This paper presents the successes achieved during the construction, commissioning and testing of an innovative approach to stationary reflector/tracking absorber (SRTA) systems that demonstrate the viability of this kind of solar thermal solution. This novel approach is based on a Fresnel concept of a classical SRTA, which leads to cost reductions thanks to reducing the height reached by the solar field. In addition, it provides the SRTA systems with another extra layer of adaptability to different climatic, orographic and even economic situations. In order to demonstrate the feasibility of this solution, the MOSAIC project has constructed and commissioned a prototype based on this approach, surpassing challenges such as the flexible piping and showing new improvements that could be introduced in the future MOSAIC modules. The first tests have been conducted on this prototype demonstrating, still under suboptimal operational conditions, an efficiency of up to 18.6 % and the possibility to operate this system using molten salts for high output temperatures that could make the most of the 3D concentration. The modularity, versatility and adaptability demonstrated by this concept all along the project development lead to a wide portfolio of opportunities to integrate the MOSAIC concept in a variety of scenarios, free space availabilities, and different applications, while maintaining a reduced cost of energy production.
LUA Celebration of the 6th edition of the World Logic Day
Authors: Beziau Jean-Yves 
Published: January 2024

The celebration will be held from Cusco (Peru) during [SALOME 1: the first South American LOgic MEeting ](https://www.salome2024.org)Round Table with, Luis Felipe Alegre, Jasmin Özel, Juan Redmond, Philip WelchInterview with Jean-Yves Beziau by Caroline Pires Ting
[Kurt Gödel: Deceased on the World Logic Day ! ](https://www.logica-universalis.org/wld6)