bluuebunny/crossref_metadata_2025_split huggingface dataset:
La communication des soins palliatifs : une incommunication féconde
Authors: Drillaud Frédérique 
Published: January 2025

Cet article est issu d’une thèse en Sciences de l’information et de la communication qui analyse la manière dont les soins palliatifs « font société » en agençant des médiations face à la mort. Différents terrains en soins palliatifs ont permis de percevoir que des enjeux y sont pratiqués quotidiennement au sein d’équipes interdisciplinaires, dans ce que forme la culture palliative. Nous souhaitons contribuer à la compréhension de cette culture en montrant qu’elle est sous-tendue de manière constante par des références implicites à ce que nous avons nommé l’effet-miroir de la mort sur la vie et la dimension existentielle, deux dimensions constructives de cette culture. C’est ainsi qu’apparaissent des enjeux communicationnels et de soin, en venant questionner une logique d’organisation autour de l’incommunicable que représente la mort. En soins palliatifs, l’incommunication ne représente pas un échec mais le support de la création de leurs pratiques. Elle est le commencement de la mise en œuvre d’une communication orchestrale autour du prendre soin.
Experiences of nurses and patients with the implementation of the CCMDD programme
Authors: Sekopa Ragosebo P. , Netangaheni Robert T. 
Published: January 2025

Background: The Central Chronic Medicines Dispensing and Distribution (CCMDD) programme has good benefits for both patients with chronic conditions and nurses if it is effectively implemented. In most of the Sekhukhune Primary Health Care (PHC) facilities, the implementation of the CCMDD programme has been highly challenging but at the same time very beneficial.Aim: The purpose of this study was to describe the experiences of nurses and patients following the implementation of the CCMDD programme in Sekhukhune clinics.Setting: Nine of the Sekhukhune district clinics in Limpopo province, South Africa, were used as study sites.Methods: The qualitative research approach with a descriptive and explorative research design was used in this study. Data were acquired through 45 one-on-one semi-structured interviews, with Sekhukhune PHC nurses managing the CCMDD programme and patients with chronic conditions who are enrolled in the programme, and then analysed thematically.Results: Positive experiences included overcrowding and workload reduction, saving of time and money for transport, improves medication adherence, reduction in incidents of file loss, reduction in patient waiting times, preservation of clinic drug supplies and easy and convenience. However, negative experiences such as shortage of staff, the lack of communication and information on the CCMDD programme hindered the effectiveness of the CCMDD programme.Conclusion: Both nurses and patients of Sekhukhune PHC facilities had positive and negative experiences with regard to the implementation of the CCMDD programme; hence, strategies to improve the programme are needed to be developed.Contribution: The study contributes by providing recommendations for nurse training in the CCMDD programme, in order to improve service delivery processes of the implementation of the CCMDD programme in Sekhukhune PHC facilities.
The Effect of Acupuncture along with Conventional Therapies on the Treatment of Allergic Rhinitis: A Clinical Trial
Authors: Hashemi Sayed Mostafa , Mokhtarinejad Farhang , Abtahi Forooshani Seyed Mojtaba , Rezvani Habibabadi Mehran 
Published: January 2025

Background:
Acupuncture is one of the most important components of modern complementary medicine. Given its mechanism of action and efficacy, researchers have been recently attracted to address its efficacy in the treatment of allergic rhinitis (AR). Therefore, the present study aimed at evaluating the effect of acupuncture along with conventional therapies on the treatment of AR.

Materials and Methods:
The present randomized, clinical trial was performed on 51 patients with AR. All patients underwent standard AR treatment under the supervision of a specialist physician. Twenty-four patients were treated with acupuncture and 27 patients were considered as the control group. The improvement degree of AR symptoms was evaluated and recorded at baseline, 2 weeks, and 6 weeks after the treatment.

Results:
The results of this study revealed that a decrease in the runny nose score with a mean of 4.59 ± 3.04 and a decrease in the sneezing score with a mean of 5.30 ± 2.92 were significantly more than those of the control group with a means of 2.85 ± 1.56 and 2.78 ± 1.28, respectively (P value < 0.05). In addition, the frequency of nasal congestion, nasal itching, and tearing was significantly lower in the acupuncture group as compared with the control group (P value < 0.05).

Conclusion:
According to the results of the present study, although conventional AR treatments can be effective in reducing the symptoms of this disease, the use of acupuncture along with conventional AR treatments has been able to play an effective role in improving and reducing the severity of AR symptoms.
Body image victimization and eating distress in young adult females
Authors: Singh Priya , Gupta Aarzoo 
Published: January 2025

Abstract

Context:
Eating distress syndrome (EDS) is characterized by distressing and conflicting thoughts about the body shape and eating behaviors accompanied by self-imposition of strict dietary and/or exercise regimes in the absence of any significant weight loss. EDS has a prevalence of nearly 11% and is associated with psychological distress, internalizing and externalizing problems, lesser well-being, and reduced quality of life.

Aims:
The study aimed to assess the relationship between eating-related messages and body image victimization with EDS in young adult females.

Settings and Design:
Purposive sampling was employed to approach an estimated sample size of 151 young adults (18–26 years). The data were collected online using e-consent through social media platforms such as Facebook, Twitter, and Instagram through Google Form (GF).

Materials and Methods:
There were a total of 403 respondents to GF comprising of Caregiver Eating Messages Scale, Body Image Victimization Experience Scale, and Eating Disorder Examination-Questionnaire Short. A total of 151 participants were recruited from 403 as per defined criteria.

Statistical Analysis Used:
Descriptive statistics, correlation, and regression analysis were used to tests the findings.

Results:
Restrictive or critical messages had a positive relationship and accounted 12% chance of occurrence of EDS. The frequency of experiences of body image victimization from peers (6%) had a greater predictive value than that from the parents (3%). Similarly, the impact of body image victimization by peers (9%) contributed more than that from the parents (4%) in the occurrence of EDS.

Conclusion:
Remarks or comments related to eating and appearance tend to determine how an individual perceived oneself and the course of one’s food habits or choices.
Prevalence and Associated Factors of Infertility among Married Couples of Kunnathukal Panchayath in Trivandrum District
Authors: Vannya M S , Singh Blessed , Usha Christopher , Joice Suba Y , Gladston Jibin V. 
Published: January 2025

Abstract

Background:
Infertility is a serious health issue worldwide, and it has been a neglected area among studies related to maternal and child health. There is a need for evidence-based knowledge regarding the prevalence of infertility and its determinants. The aim of this study was to estimate the prevalence of infertility and its associated factors among married couples residing at Kunnathukal Panchayath in Trivandrum district.

Materials and Methods:
A community-based cross-sectional study was conducted among 1270 married couples residing at Kunnathukal Panchayath, selected using a cluster sampling technique. Data was collected using a pretested predesigned semi-structured questionnaire, entered into MS Excel, and analyzed using SPSS version 20. The Chi-square test, Fischer’s exact test, and Mann–Whitney U test were used as tests of significance. Binary logistic regression analysis was performed to find independent predictors of infertility. P value < 0.05 was considered as statistical significance.

Results:
Prevalence of infertility was found to be 12%, and among them, majority (65.8%) had primary infertility. The factors found to be significantly associated with infertility are occupation of females, age at time of menarche, dysmenorrhea, type of dysmenorrhea, dyspareunia, fibroid uterus, hypothyroidism, and BMI. In multivariate analysis, dysmenorrhea, type of dysmenorrhea, and uterine fibroid emerged as predictors of infertility.

Conclusion:
Prevalence of infertility was found to be 12% in this study, which is almost similar to our state’s average (10.5%) according to DLHS-3. Dysmenorrhea, type of dysmenorrhea, and uterine fibroid emerged as predictors of infertility. The preventive and intervention activities addressing infertility should give more priority to these predictors.
Melioidosis in a child with nephrotic syndrome
Authors: Sahu Sanjay Kumar , Behera Chinmay Kumar , Pradhan Sarbeswar , Sahoo Jiten Kumar , Nikhila Gannavarapu Phanisri , Boggavarapu Lakshmi Meghana 
Published: January 2025

Abstract
Melioidosis, caused by Burkholderia pseudomallei, presents with a wide range of clinical manifestations. We report the case of an 8-year-old boy with nephrotic syndrome in remission, presenting with high-grade fever and painful limb swellings. Initial investigations revealed mild leukocytosis, thrombocytosis, and Pseudomonas aeruginosa in urine culture. Despite treatment, fever persisted until blood cultures identified B. pseudomallei. Antibiotics were upgraded to meropenem and doxycycline. Following abscess drainage and adjusted therapy, the patient stabilized. This case highlights the importance of considering melioidosis in pediatric patients with persistent fever and abscesses in endemic areas.
Management of pancreatic fluid collections: A concise review
Authors: Sahu Saroj Kanta , Mallick Bipadabhanjan , Nath Preetam , Praharaj Dibyalochan , Giri Suprabhat , Panigrahi Sarat Chandra , Anand Anil Chandra 
Published: January 2025

Abstract
A pancreatic fluid collection (PFC) is a local complication of acute pancreatitis. Most PFCs spontaneously resolve and only a minor group of patients need therapeutic intervention. When conservative treatment fails, patients with symptomatic or infected PFCs undergo drainage, either with or without necrosectomy. Three drainage techniques, i.e., endoscopic, percutaneous, and minimally invasive surgery (MIS), are complementary to achieve the symptomatic resolution of the PFC. Endoscopic drainage (ED) with a high technical and clinical success rate has become the current standard of care for mature PFCs. Among the ED techniques, endoscopic ultrasound-guided transmural drainage (EUS-TD) is preferred over conventional transmural drainage for pancreatic pseudocysts or walled-off necrosis (WON). For PFC that is not encapsulated and <4 weeks old, percutaneous catheter drainage ± sinus tract endoscopy works well and is lifesaving in people with abdominal compartment syndrome. Pancreatic necrosectomy is an adjunctive procedure in patients who fail to improve after initial transmural or percutaneous drainage. MIS plays a role if the PFC shows inadequate response to combined drainage and debridement procedures, with open necrosectomy the last resort. Infected pancreatic necrosis is the most dreaded complication of acute necrotizing pancreatitis with a significantly high mortality rate (20%–30%). The “step-up” approach is recommended for infected as well as symptomatic WON. The “surgical step-up” and the “endoscopic step-up” are preferred for infected acute necrotic collection and infected WON, respectively. Various adjunctive methods such as stopping proton-pump inhibitors, hydrogen peroxide irrigation, and nasocystic catheter irrigation help in the earlier resolution of WON by reducing the number of sessions of direct endoscopic necrosectomy (DEN). Using lumen-apposing metal stents for EUS-guided drainage of PFCs has revolutionized the technique with more effective drainage and provides a conduit for DEN.
Anti-Candidal Action of Epigallocatechin Gallate as Intracanal Medicament—A Microbiological and Dentin Model Study
Authors: Shobana Shekar , Sujareetha Anandavelu , Venkatesan Sokkalingam M. , Geethapriya Nagarajan , Sarathy S Sarath , Natarajan Raghunathan 
Published: January 2025

ABSTRACT

Aim:
To evaluate the antifungal activity of Triple Antibiotic Paste (TAP) with Epigallocatechin Gallate (EGCG) against Candida albicans.

Materials and Methods:
Disk diffusion test: Thirty Kirby–Bauer disks were soaked in: Group 1—TAP (ciprofloxacin, minocycline, and metronidazole in saline); Group 2—TAP + EGCG + saline; Group 3—EGCG + saline; Group 4—Fluconazole. Disks were dried, placed in a C.albicans suspension, and incubated at 37°C for 24 hours. Zones of inhibition were measured.

Simulated Dentine Study:
Forty single-rooted teeth were decoronated to 12 mm, cleaned and shaped with ProTaper files, and irrigated with saline. Canals were inoculated with C.albicans, treated with medicaments after two days, and incubated for three days. After saline irrigation, sterile absorbent points were placed in Sabouraud Dextrose Agar for 48-hour incubation at 37°C. Colony-forming units (CFUs) were counted.

Results:
Fluconazole produced the largest zones of inhibition, significantly larger than EGCG, EGCG + Fluconazole, and TAP + EGCG (P < 0.001).

Conclusion:

C.albicans is susceptible to EGCG, with Fluconazole exhibiting the greatest antifungal activity.
A Cross-Sectional Study: Dentists’ Knowledge, Attitudes, and Perceptions of the Role of Plasma-Rich Protein and its Applications in Tooth Movement Rate
Authors: Shaga I Bevin , Elangovan Bharathi , Acchuthakrishnan  , Devika J , Anitha K. , Moulvi SMM , Nagappan Nagappan 
Published: January 2025

ABSTRACT

Aim:
This study aimed to assess dentists’ perceptions and knowledge of plasma-rich protein and uses in rate of tooth movement.

Material and Methods:
This online survey, which is cross-sectional in nature, is being done among dental care providers. The 500 participants’ self-administered questionnaires on PRP in orthodontic tooth mobility. The statistical analysis was performed using the Statistical Package for Social Sciences (SPSS) (V 22.0). The frequency distribution was calculated.

Results:
The survey revealed that, 452 (90.4%) were aware of the PRP preparation process, and 400 (20%) were aware of the use of plasma-rich protein (PRP) to accelerate tooth movement. Regarding the primary PRP ingredients and the PRP procedure for quickening tooth movement in orthodontics, 66.4% had given the right responses. The majority of dentists were sufficiently knowledgeable about both invasive and non-invasive methods for quickening the movement of teeth.

Conclusion:
The study’s conclusions demonstrated that dental professionals were aware of the most recent developments in dental PRP application and its protocols, but additional research has to be done to educate everyone about these recent developments. Future experimental research on PRP in dental practices will be necessary in order to further develop our awareness of it.
Cytotoxic Effects of Srikhandasavam on Ethanol-Induced Neurotoxicity in Hippocampal Cell Cultures
Authors: Kondamma S , Kalaivannan J. , Jones Sumathi , Janaki C.S. , Sheriff Dhastagir , Prabhu K. , Balakrishnan Deepalakkshmi , Sambasivam Shyamala 
Published: January 2025

ABSTRACT

Background:
Srikhandasavam is a traditional Ayurvedic herbal formulation known for its potential therapeutic properties, particularly in enhancing overall vitality and digestive health. It is composed of a blend of natural ingredients, including sandalwood, which are fermented to enhance their medicinal potency.

Aim:
The present study investigates the neuroprotective effects of Srikhandasavam on hippocampal neurons subjected to ethanol-induced neurotoxicity.

Methods:
The primary focus was to assess cell viability and cytotoxicity in the presence of Srikhandasavam at various concentrations, using hippocampal cell cultures.

Results:
The cytotoxicity results indicated a significant impact at higher concentrations, with 50.3% cell mortality observed at 200 µg/mL of Srikhandasavam. Conversely, the MTT assay revealed that Srikhandasavam offered notable protection against ethanol-induced neurotoxicity, with a 71.8% cell viability rate at the same 200 µg/mL concentration.

Conclusion:
These findings suggest that Srikhandasavam as a potential neuroprotective agent, capable of mitigating ethanol-induced damage in hippocampal neurons while maintaining cell viability at therapeutic concentrations.
Comparative Evaluation of Microtissue-Engineered Root Dentin with Three Different Nanoparticles in Improving Fatigue Resistance of Endodontically Treated Teeth – An In Vitro Study
Authors: Balavaishnavi G , Chakravarthy Dhanavel , Shajahan Shahana , Sornamalar M , Raja S Vijaya 
Published: January 2025

ABSTRACT

Aim:
This study aims to analyze the fatigue resistance, surface mechanical properties, and biomechanical responsiveness of microtissue-engineered root dentin using cellulose nanofibers, hydroxyapatite nanocrystals, and walnut shell nanopowders.

Methodology:
The objectives are to evaluate the differences in fatigue resistance and biomechanics and surface mechanical characteristics by infiltrating these nanomaterials into the root canal of endodontically treated teeth. Forty human permanent single-rooted teeth were collected with the patient’s consent. Fatigue resistance was measured using cyclic loading, and surface roughness was measured by scanning electron microscopy (SEM).

Results:
The results showed a fatigue resistance of 36.81 ± 4.58 MPa, attributed to the availability of calcium ions at 9%, the highest compared to other groups. Non-microtissue-engineered root dentin exhibited a stress resistance of 12.3 ± 3.1 MPa and a strain resistance of 4.1 ± 1.1 MPa. Walnut shell nanopowder (WNP) exhibited higher fatigue resistance than other groups (P > 0.05).

Conclusion:
Root dentin engineered with HaNPs showed a fatigue resistance of 36.81 ± 4.58 MPa and surface roughness of 4.2 ± 0.5 MPa, attributed to the availability of calcium ions at 9%, the highest compared to other groups. Non-microtissue-engineered root dentin exhibited a fatigue resistance of 12.3 ± 3.1 MPa, while microtissue-engineered root dentin showed 36.81 ± 4.58 MPa, which is three times higher.
Comparative Assessment of Blood Parameters Including RBC, Hb, PCV, Red Cell Indices, Serum Ferritin, and Salivary Candidal Growth in Female Patients with Iron Deficiency Anemia and Iron Deficiency
Authors: Saba Asra , Komali Garlapati , Shrivastava Deepti , Alghafli Mohammed A. , Alazmi Faisal Maqbul , Aljudaya Salman A. S. , Heboyan Artak , Srivastava Kumar Chandan 
Published: January 2025

ABSTRACT

Background:
Iron deficiency anemia (IDA) is a microcytic-hypochromic anemia prevalent in African and South Asian countries including India. Along with systemic, it presents various oral manifestations that can be diagnosed in dental setups. Literature suggests that there is a state of iron deficiency before it manifests as anemia, which eventually creates an immunodeficient body state that predisposes to various opportunistic infections such as oral candidiasis.

Objectives:
The present study was designed to evaluate and compare various components of the blood picture including the hemoglobin (Hb%), red blood cell (RBC) count, RBC indices, hematocrit, peripheral blood smear and serum ferritin between iron deficiency (ID), IDA, and healthy subjects. The study also attempts to compare and assess the salivary samples of ID for Candida growth.

Material and Methods:
A total of 252 female patients of age groups ranging from 18 to 70 years were selected. The study consisted of three study groups, namely, Group A, IDA patients (clinical manifestations with pallor); Group B, ID patients (clinical manifestations without pallor); and Group C, age-matched healthy controls, with 84 in each group. The blood samples were collected to evaluate the hematological parameters including Hb%, RBC count, RBC indices, hematocrit, peripheral blood smear, and serum ferritin. Later, a saliva sample was collected from all study groups to assess the Candida growth. The obtained data were subjected to statistical analysis using SPSS version 20.0 software.

Results:
The results demonstrated that ID patients had normal blood parameters as healthy controls except for serum ferritin, while IDA patients had significantly (P < 0.001) lower hemoglobin, RBC count, and blood cell indices, specifically mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and hematocrit compared to ID and healthy controls. A significant finding is that like IDA patients, ID patients exhibited reduced serum ferritin levels. Contrary to the IDA group, only a small percentage of ID patients had Candida growth, although this was not statistically significant.

Conclusion:
Within the limitations of the current study, the results showed significantly reduced serum ferritin levels in ID, while other parameters were within the normal limits, and found tendency to develop Candida growth compared with the control subjects. Further studies are warranted to establish the association and causal relationship.
Association of Triglycerides and HbA1c Levels with Stages of Invasive Ductal Breast Cancer: A Prospective Study
Authors: Helena Vemuri , Suresh Arumugam , Muninathan Natrajan , Baskaran Kuppusamy , Khan Siddique Ahmed 
Published: January 2025

ABSTRACT

Background:
This prospective study investigates the association between triglyceride (TG) levels and HbA1c values with different stages of invasive ductal breast cancer (IDC) in female patients. Metabolic alterations, including dyslipidemia and hyperglycemia, are increasingly recognized as potential factors associated with cancer progression.

Methods:
A total of 150 female patients diagnosed with IDC were included in the study, categorized into four stages of the disease. Triglyceride levels were measured using colorimetry, and HbA1c values were determined using the ion exchange resin method. Descriptive statistics and distributions of TG and HbA1c values were analyzed across the cancer stages.

Results:
In Stage 1, patients had a mean TG level of 347.5 mg/dL and a mean HbA1c of 10.2%. These values declined in subsequent stages, with Stage 4 patients showing a mean TG level of 208.6 mg/dL and a mean HbA1c of 6.9%. A majority of Stage 1 patients (n = 35) had TG levels between 200 and 499 mg/dL, while Stage 4 had the highest number of patients with TG levels below 150 mg/dL (n = 6). Additionally, a significant proportion of Stage 1 patients had HbA1c values ≥10% (n = 17), indicating poor glycemic control. As the disease progressed, this proportion decreased, with only two patients in Stage 4 having HbA1c levels ≥10%.

Conclusion:
This study suggests a correlation between lower TG and HbA1c levels and more advanced stages of IDC. These findings highlight the importance of metabolic factors in IDC progression and may inform future research on potential therapeutic targets.