bluuebunny/crossref_metadata_2025_split huggingface dataset:
APPROACHES TO MODELING AUTISM IN ATTENTION DEFICIT HYPERACTIVITY DISORDER
Authors: Трактиров Д. , Мальсагова Э. , Муружева З. , Пестерева Н. , Карпенко М. 
Published: October 2023

Среди психических расстройств у детей наиболее распространенными и социально значимыми являются синдром дефицита внимания с гиперактивностью (СДВГ) и расстройства аутистического спектра (РАС). Уже доказано, что РАС и СДВГ имеют ряд общих звеньев патогенеза и характеризуются некоторыми общими клиническими особенностями, но факторы, действие которых приводило бы к развитию СДВГ, РАС или СДВГ + РАС, еще не описаны, что обусловливает необходимость разработки животных моделей такого состояния. Многие исследовательские группы рассматривают РАС и СДВГ как полигенные заболевания. Однако выявление все новых и новых генов-кандидатов не приближает нас к пониманию вопроса их этиологии. Согласно современным представлениям, для развития РАС + СДВГ необходимо сочетанное действие, как минимум, генетического и церебрально-органического факторов, поэтому для моделирования основных симптомов данного состояния оптимально использовать препараты, вызывающие органическое поражение головного мозга у животных с генетически детерминированными нарушениями. При данных заболеваниях генетически детерминированные нарушения, главным образом, должны затрагивать моноаминергические нейромедиаторные системы, потому что именно они определяют течение всех фундаментальных для ЦНС процессов. В данном обзоре приводятся доводы в пользу того, что крысы с нокаутом гена — транспортера дофамина (генетический фактор) и развившимся вальпроатным синдромом (церебрально-органический фактор) могут быть использованы для изучения патогенеза РАС в сочетании с СДВГ.
Among neurodevelopmental disorders in children, the most common and socially significant are attention deficit hyperactivity disorder (ADHD) and autism spectrum disorders (ASD). It has already been proven that ASD and ADHD have a number of common components of pathogenesis and are characterized by some common clinical features, but the factors that would lead to the development of ADHD, ASD or ADHD + ASD have not yet been described, which necessitates the development of animal models of this condition. Many research groups consider ASD and ADHD as polygenic diseases. However, the identification of more and more new candidate genes does not bring us closer to understanding the etiology. According to modern concepts, the development of AS + ADHD requires a combined effect of at least a genetic and cerebro-organic factor, therefore, to model the main symptoms of this condition, it is optimal to use drugs that cause organic brain damage in animals with genetically determined disorders. In these diseases, genetically determined disorders should mainly affect monoaminergic neurotransmitter systems, because they determine the course of all fundamental processes for the CNS. This review argues that rats with knockout of the dopamine transporter gene (genetic factor) and developed valproate syndrome (cerebral-organic factor) can be used to study the pathogenesis of ASD combined with ADHD.
The Use of DFT-Based ab-initio Technique to Determine the Stability Difference in B2 Ti-PGM Compounds
Authors: Diale Ramogohlo , Nkomo Duduzile , Ngobe Bongani , Phasha Maje 
Published: October 2023

In this chapter, the density functional theory (DFT) based first-principles approach is used to predict the underlying lattice properties associated with the phase transformation and stability of B2 phase in titanium-platinum group metal (Ti-PGM) compounds. This ab- initio technique provides a good platform to accurately explore phase stability variation between the successful Ti-PGM shape memory alloys (SMAs) (Ti50M50, M = Rh, Pd, Ir, Pt) and other B2 Ti-PGM compounds that do not show any shape memory effect (SME), such as Ti50Os50 and Ti50Ru50. The B2 TiFe, TiNi and TiAu have also been considered in this chapter in order to draw similarities and differences. Amongst the predicted results, the heat of formation was calculated to determine the thermodynamic stability, whereas the total densities of states were used to evaluate the electronic stability of these compounds. Insights on the mechanical stability of the B2 crystals were derived from the calculated elastic constants. Mechanical instability was revealed in some compounds, indicative of a possible phase transition responsible for the intrinsic shape memory character. Although an attempt to correlate this mechanical instability with imaginary frequencies established from the phonon dispersion curves is made, the correlation is not yet conclusive due to some discrepancies observed in TiNi.
Preoperative Education Against Anxiety on Patient Pre Retinal Ablasio Surgery at The Eye Hospital Invitation Surabaya
Authors: Dewi Retno Puspitosari  , Suhartini  , Nurhidayah  
Published: October 2023

Retinal detachment is a disease of decreased vision due to the separation of the retinal cone cells and rod cells from the retinal epithelial cells. The most common response in preoperative patients is anxiety. Preoperative anxiety can cause palpitations, palpitations, feeling like fainting, increased blood pressure, and increased pulse pressure. The purpose of this study was to determine the effectiveness of providing preoperative education on anxiety in preoperative retinal detachment patients at Undaan Eye Hospital, Surabaya. The research design was a quasi-experimental study with a one group pre-test – post-test design approach. The results showed that the patient's anxiety level before being educated was half of the respondents with severe anxiety, the anxiety level after being educated was almost half of the respondents who had no anxiety and mild anxiety. Based on SPSS calculations using the dependent sample t-test, the value of p = 0.000 (<0.05) is obtained at the sig.(2.tailed) value. So, there is a difference in the level of anxiety before and after being given education to preoperative retinal detachment patients at the Undaan Eye Hospital, Surabaya. This means that the education given to preoperative retinal detachment patients is effective in reducing anxiety levels. The conclusion of this research is that there is effectiveness in providing education on anxiety levels at the Mata Undaan Hospital, Surabaya.
Effectiveness of Health Education about Personal Hygiene on the Personal Hygiene Behavior of Young Women at the Darussalam Islamic Boarding School
Authors: Titik Juwariyah  , Agus Priyanto  , M.Khoirudin  
Published: October 2023

Personal hygiene is a person's efforts to maintain personal hygiene to obtain physical and psychological well-being. Personal hygiene is needed to prevent various diseases. One way to prevent the spread of disease caused by personal hygiene is by providing health education. The aimed of this research to determine the effect of health education about personal hygiene on the personal hygiene behavior of young women. The design used Quasy experimental using a one group pre-post test design approach. The sample in the research was 79 respondents taken using purposive sampling technique. Data were analyzed using the Willcoxon Signed Rank Test with significance α <0.05. The results of the study showed that before being given health education, the majority of personal hygiene behavior was adequate, 59 respondents (74.5%) and personal hygiene behavior after health education showed that almost all 71 respondents (89.8%) had good personal hygiene behavior. The results of further analysis showed that there was a significant difference in personal hygiene behavior between before and after health education (p-value=0.000; α <0.05). Health education can change respondents' behavior towards personal hygiene in young women, so it is recommended that the public pay more attention to personal hygiene to avoid various diseases, especially skin diseases.
Improved Oil Lubricated Bearings via 100 Bond® Laser Babbitting Process
Authors: Vázquez Jose Antonio , Garcia Beatriz , Taylor Steven 
Published: October 2023

The paper discusses the methodology for and performance improvements gained using the patent pending 100 Bond® Laser Babbitting Process developed by Wartsila Shaft Line Solutions. This process is currently being used at the Wartsila Iberica facility for commercial Line Shaft and Thrust Bearings. The discussion covers various testing that has been performed including testing that was 2188 for ASTM B23 Grade 2 Babbitt in accordance with DOD-STD-2183.
Fatigue, hardness and bond strength are all improved from the refined microstructure of the babbitting material. The automated process eliminates the various chemicals used in traditional babbitt casting as well as the handling of molten babbitt providing significant reduction of the environmental concerns, health & safety risks and quality control issues. Together these benefits allow for improved bearing repairability, ability to produce more complex bearing shell geometries on a wide variety of base metals, and overall improvement of the hydrodynamic bearing performance.
Direitos Humanos, Política E Conhecimento: Uma Abordagem A Partir De América Latina
Authors: Andrey Borges Pimentel Carlos Ugo Santander, 
Published: October 2023

O discurso contemporâneo acerca dos direitos humanos são bastante difundido. O teor do seu conteúdo consagra valores que professam a realização dos ideais de toda a humanidade, prometendo a plena emancipação do ser. Todavia, o momento de plenitude dos direitos humanos inaugurado com a hegemonia estadunidense no plano internacional tem suscitado tanto questionamentos sobre a sua eficâcia quanto críticas em relação a apropriação de seu conteúdo restrito, casa sempre, ao campo epistémico do direito positivo.
Pengaruh Metode Outdoor Study Terhadap Hasil Belajar IPA Siswa Kelas IV Di SDN 095130 Senio Bangun
Authors: Nora Elysabeth Br. Manurung  , Pasaribu Eva Hetri , Simarmata Radode Kristianto 
Published: October 2023

Pendidikan memegang peranan yang sangat penting di dalam kehidupan karena pendidikan merupakan sarana dalam proses peningkatan perubahan tingkah laku kearah yang positif untuk mencapai tujuan yang telah ditentukan. Melalui pendidikan seseorang mampu tumbuh, mengembangkan pengetahuan dan peningkatan kualitas hidup dan martabat manusia dengan menggunakan semua kemampuan yang dimiliki sehingga tidak bergantungan pada orang lain. Jenis penelitian yang digunakan adalah penelitian kuantitatif. Design penelitian yang digunakan adalah metode Pre-eksperimental design jenis One Group Pretest-Postest. Dalam tahap awal dilakukan Pre-test untuk mengetahui kemampuan awal belajar siswa sebelum ada perlakuan dan Post-test untuk mengetahui kemampuan akhir belajar siswa setelah adanya perlakuan. Hasil dari penelitian ini adalah Beradasarkan nilai tertinggi dari hasil belajar pretest siswa kelas IV SD Negeri 095130 Senio Bangun pada pembelajaran subtema Keberagaman Makhluk Hidup di Lingkunganku adalah 60 dan terendah adalah 35 dengan nilai rata-rata 45,57. Sedangkan nilai tertinggi dari hasil belajar posttest siswa adalah 100 dan terendah adalah 75 dengan nilai rata-rata 86,73 membuktikan bahwa siswa yang mendapat nilai di bawah KKM banyak berkurang. Kemudian hasil uji hipotesis dapat disimpulkan bahwa metode outdoor study berpengaruh terhadap hasil belajar setelah diperoleh thitung = 17,83 dan ttabel = 2,060 maka diperoleh thitung ≥ ttabel atau 17,83 > 2,060 maka ditolak dan Ha diterima. Ini artinya bahwa metode outdoor study memeberikan pengaruh pada hasil belajar siswa.
Access to Dental Services among Hypertensive Elderly in Peru: Exploring Patterns and Implications
Authors: Ramirez-Ortega Andrea P. , Vera-Ponce Víctor Juan , Iturregui Paucar Cori Raquel 
Published: October 2023

Background: This study was conducted to determine access to dental services in the elderly with hypertension in Peru.
Methods: Observational, analytical, and cross-sectional design. Data used for analysis in this research was collected from the Demographic and Family Health Survey of Peru (ENDES) from 2019 to 2021.
Results: A Poisson regression analysis was performed a weighted sample for calculating prevalence ratio (PR) with their 95% confidence intervals (95%CI). The multiple regression analysis did not find among the factors associated with the probability of using the dental health service, since neither the time less than two years of hypertension (PR=0.74, 95%CI 0.53 – 1.02); nor from 2 to 4 years (PR = 0.97, CI 95% 0.86 – 1.09); neither a time of hypertension from 5 years or more (PR = 0.94, CI 95% 0.85 – 1.03) were associated.
Conclusion: The study concluded that hypertensive patient over 60 years of age, despite a previous diagnosis of hypertension or not, does not attend dental service, reflecting a lack of interest and a greater risk exposure to cardiovascular complications associated with oral health.
Semantic web ecosystem based on CVE (NVD, CPE), CWE and CAPEC
Authors: Dimitrov Vladimir 
Published: October 2023

CVE (NVD, CPE), CWE and CAPEC are databases in the Cybersecurity area sponsored and maintained by the US government. These are lists (databases) organized in taxonomies where it is appropriate. They contain information about known vulnerabilities, weaknesses and attacks. CVE (NVD, CPE), CWE and CAPEC are the corner stone in many cybersecurity tools.The usage of traditional database systems for the tasks in the cybersecurity require extended knowledge and skills in querying for identification of vulnerabilities, weaknesses and attacks. CVE (NVD, CPE), CWE and CAPEC contain hidden facts and relationships (knowledge) buried in the data. This knowledge can be effectively accessed by the Semantic web tools.The paper presents an approach for transition to the Semantic web of above-mentioned databases. The approach is presented in illustrative way. This means without duplication with information about the contents available for CVE (NVD, CPE), CWE and CAPEC.
Association Between Disease-Modifying Therapy and Information Processing Speed in Multiple Sclerosis
Authors: Aboseif Albert , Amin Moein , Bena James , Nakamura Kunio , Macaron Gabrielle , Ontaneda Daniel 
Published: October 2023

BACKGROUND:
Cognitive impairment (CI) is common in multiple sclerosis (MS). Processing speed (PS) is often affected, making it an ideal target for monitoring CI. This study aims to evaluate the association between disease-modifying therapy (DMT) use and intensity and longitudinal changes in Processing Speed Test (PST) scores for individuals with MS.

METHODS:
A retrospective analysis of individual PST scores at a single MS center was conducted. Individuals with 2 or more PST assessments were included. Scores on the PST were compared longitudinally between those who had been on a DMT for 2 or more years and those who had been off a DMT for 2 or more years and between those on high-efficacy DMTs and those on low-/moderate-efficacy DMTs. A linear regression model was approximated to evaluate the rate of cognitive change over time. A propensity score adjustment was conducted using a multivariable logistic regression.

RESULTS:
The cohort was 642 individuals, 539 on DMT and 103 off DMT. Median age and disease duration was 49.7 (IQR 42.4-57.9) and 16.6 years (IQR 9.3-23.0) in the DMT group, and 58.9 (IQR 52.2-65.3) and 20.0 years (IQR 14.1-31.4) in the non-DMT group. Both cohorts were predominantly female (75% DMT, 79.6% non-DMT), with a mean of 4 assessments (IQR 3-5), and an average monitoring duration of 1.9 years (1.2-2.4) in the DMT group, and 1.8 years (1.4-2.4) in the non-DMT group. After adjusting for multiple factors, DMT status and intensity were not found to be significant predictors of longitudinal PST change.

CONCLUSIONS:
Neither DMT status nor intensity was a significant predictor of cognitive processing speed over a period of approximately 2 years. Future prospective studies are needed to further support these findings.
Identification of Ectoparasites and Endoparasites in Snakehead Fish (Channa striata) and Climbing Perch Fish (Anabas testudineus) Caught in the Sebangau River of Indonesia
Authors: Minggawati Infa , Agustinus Frid , Inel Lukas , Franciska Holla , Nur Akhmad Fakhrizal 
Published: October 2023

Ectoparasites are parasites that can infect the external organs of fish (skin, gills and the outer surface of the body) while endoparasites are parasites that infect the internal organs of fish. This study aims to determine the types of ectoparasites and endoparasites that infect snakehead fish (Channa striata) and climbing perch fish (Anabas testudineus). Sampling was carried out at the Sebangau River while the identification was carried out at the Fish Quarantine Station, Quality Control and Safety of Fishery Products in Palangka Raya. Examination of ectoparasites includes mucus, gills, scales, and fish fins. Examination of endoparasites by observing the organs of the fish such as liver, meat, intestines and stomach. There are eight types of ectoparasites in snakehead fish, namely Trichodina sp, Dactylogyrus sp, Gyrodactylus sp, Apiosoma sp, Tetrahymena sp, Aelosoma sp, Lamproglena sp, and Henneguya sp, while there are four types of endoparasites in snakehead fish, namely Camallanus sp, Procamallanus sp, Neoechynorynchus sp , and Senga sp. There are five types of ectoparasites in the climbing perch fish caught in the Sebangau River, namely Trichodina sp, Dactylogyrus sp, Aelosoma sp, Myxobolus sp, and Epistylis sp. Meanwhile, there is only one type of endoparasite that attack snakehead fish, namely Procamallanus sp. The total prevalence of snakehead fish’s ectoparasites was 81.7%, with an intensity level of 6.1 individual parasites per fish. The total prevalence of ectoparasites in climbing perch fish is 45%, with an intensity level of 5.4 individual parasites per fish. The total prevalence of snakehead fish endoparasites is 65%, with an intensity level of 9.8 individual parasites per fish. The prevalence of climbing perch fish’s endoparasites is 31.7%, with an intensity level of 19 individual parasites per fish.
Organic Hydroponics: The Future of Farming
Authors: Ashpreet  , Reji Aneetta P. , Kaushal Shilpa , Shubham  
Published: October 2023

The review “Organic Hydroponics: The Future of Farming” offers a comprehensive analysis of the developing sphere of organic hydroponics, that integrates hydroponic technology with organic agriculture principles. The paper covers the ideas of hydroponics and organic farming while outlining their advantages and disadvantages in contemporary agriculture. It investigates how organic practices are aligned with hydroponic elements such as substrates, fertilizer solutions, pest and disease management. The paper explores ways to apply organic principles while taking into account economic factors, such as using organic sources of nutrients and bio-based pest control. In the study, organic and inorganic hydroponic systems are compared and discussed in terms of yield, quality, utilization of resources, and sustainability. Overall, the report emphasizes the potential advantages of combining hydroponic technology and organic farming methods, providing information for additional study and comprehension of sustainable crop production.
Helicoverpa armigera (Hubner) Associated Cross Resistance Patterns in South Indian Crop Ecosystem
Authors: Upendhar S.  , Satyanarayana J.  , Vani Sree K.  
Published: October 2023

Aim: To study the cross resistance patterns associated with Mahaboobnagar, Raichur, Nagpur populations of Helicoverpa armigera (Hubner).
Study design: Bioassay
Place and Duration of Study: The experiment was carried out from February 2010 to May 2011 at Department of Entomology, College of Agriculture, Rajendranagar, Hyderabad, Telangana.
Methodology: Helicoverpa armigera was selected for indoxacarb in F1 and F2 continuously then the population subjected to different selected insecticides to know the cross resistance patterns associated.
Results: Mahaboobnagar population recorded 1.109 and 0.816 fold resistance at LD50 and LD90, respectively, while Raichur population has developed still higher levels of relative resistance by 1.591 and 0.846 fold when compared with the Nagpur population at LD50 and LD90, respectively. Similarly, the Raichur population has developed 1.435 and 1.037 folds relative resistance at LD50­ and LD90, respectively as compared with the Mahaboobnagar population.
The Mahaboobnagar population resistant to indoxacarb at F3, when subjected to selected insecticides like cypermethrin, methomyl, spinosad showed a negative cross resistance ratio of 0.665, 0.830, 0.916 to cypermethrin, methomyl, spinosad respectively, and a positive cross resistance ratio of 1.019 to indoxacarb, while similar trend was displayed by Raichur population showing a negative cross resistance ratio of 0.932, 0.565, 0.803 to cypermethrin, methomyl, spinosad respectively and positive cross resistance of 1.036 indoxacarb further, same trend was shown by Nagpur population by displaying a negative cross resistance ratio of 0.610, 0.735, 0.519 to cypermethrin, methomyl, spinosad and positive cross resistance ratio of 1.026 to indoxacarb.
Conclusion: Continuous application of single insecticide belonging to a specific group across the generations increases the resistance from F1 to F3. Alternating the new chemistries with old conventional chemicals resulted in no cross resistance development as it was observed in all test populations.
Screening of Diesel Oil Degrading Species of Aspergillus for the Production of Different Enzymes Using Agar Plate Assay Method
Authors: Ruchika  , Garg Amar P. 
Published: October 2023

We have earlier isolated Aspergillus luchuensis, A. violaceofuscus, A. niveus, A. terreus, A. japonicus and A. ustus from naturally degraded diesel oil in the soils using nutrient rich technique. These species were cultured to produce enzyme complexes on 10% (w/v) diesel oil broth containing 0.5 and 1.0% (w/v) jaggery at 37 and 45℃ temperature separately for 7, 14 and 21 days. It was observed that all 6 species of Aspergillus produced luxuriant mycelial growth at day-7 on both temperatures, however, at 45℃, the liquid broth dried on 14th day of incubation, and therefore, secretory extracellular enzymes produced at 37℃ were screened to test the activities of amylases, gelatinases, lipases, cellulases, pectinases, proteases and manganese peroxidases using agar plate assay method. These enzymes are responsible for beaking down different bonds of the complex hydrocarbons. It was found that all 6 test species of Aspergillus produced all 7 enzymes at higher concentration at day 21 on diesel oil containing 1.0% jaggery. The production of enzyme increased with increasing period of incubation from day 7 to day 21. A. luchuensis produced highest activities of proteases, A. violacefuscus - amylases, A. niveus - gelatinases, A. terreus and A. ustus - pectinases, and A. japonicus produced highest activities of manganese peroxidases. All these enzymes contribute in the degradation of diesel oil in nature. This study revealed that the production of varying amounts of different enzymes by all these 6 species of Aspergillus has significant ecological and bioremediation potential.