bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pricing decisions in a two-period closed-loop supply chain game under asymmetric information and uncertainty
Authors: Beranek Maria , Buscher Udo 
Published: December 2023

AbstractStrategies to increase sustainability are of growing relevance for supply chains and especially for the management of production processes. In this paper, we build on existing literature in closed-loop supply chain management and consider a two-period game-theoretic model in which product returns are reused in the manufacturing process. In all scenarios, we assume that the return rate of used products is random and not known to the players at the beginning of the planning horizon, thus, they have to deal with uncertainty in period 1. In contrast to existing literature, we will also address the circumstance that the players’ level of information in period 2, after the returns have been realized, can be linked to the collection mode in the supply chain. In Scenario A, the retailer is involved in the collection of the used products and transfers them to the manufacturer, so that symmetric information is available. In Scenario B, on the other hand, the used products reach the manufacturer directly from the customer, so that the manufacturer has an information advantage over the retailer. By comparing these scenarios and a vertically integrated supply chain benchmark case, it becomes clear that, depending on the actual return rate, the presence of private information can be either beneficial or detrimental to the manufacturer. The retailer, on the other hand, can compensate for information disadvantages in most cases over the multi-period planning period due to its position as a Stackelberg leader. Regardless of the amount of a transfer payment offered to it by the manufacturer, it prefers the collection of the goods by the manufacturer itself. These findings contribute to literature on symmetric information, where, for example, a retailer-led collection is preferred (Savaskan et al. Manage Sci 50(2):239–252, 2004) or the decision depends on the amount of the transfer payment (Modak et al. J Clean Prod 171:512–528, 2018). However, we show that cooperation between the players leads to the best results not only economically but also from an ecological point of view.
Educating and Training in Research Integrity (RI): A Study on the Perceptions and Experiences of Early Career Researchers Attending an Institutional RI Course
Authors: Francesca Greco , Ceruti Silvia , Martini Stefano , Picozzi Mario , Cosentino Marco , Marino Franca 
Published: December 2023

AbstractResearch integrity (RI) is defined as adherence to ethical principles, deontological duties, and professional standards necessary for responsible conduct of scientific research. Early training on RI, especially for early-career researchers, could be useful to help develop good standards of conduct and prevent research misconduct (RM).The aim of this study is to assess the effectiveness of a training course on RI, by mapping the attitudes of early-career researchers on this topic through a questionnaire built upon the revised version of the Scientific Misconduct Questionnaire and administered to all participants at the beginning and at the end of the course.Results show that after the course, participants reporting a high understanding of the rules and procedures related to RM significantly increased (pre-course: 38.5%, post-course: 61.5%), together with the percentage of those reporting a lack of awareness on the extent of misconduct (pre-course: 46.2%, post-course: 69.2%), and of those who believe that the lack of research ethics consultation services strongly affects RM (pre-course: 15.4%, post-course: 61.5%). Early-career researchers agree on the importance to share with peers and superiors any ethical concern that may arise in research, and to create a work environment that fosters RI awareness.As a whole, results suggest the effectiveness of the course. Institutions should introduce RI training for early-career researchers, together with research methodology, integrity and ethics consultation services to support them. Senior scientists should promote RI into their research practices, and should stimulate engagement in peer-to-peer dialogue to develop good practices based on RI principles.
Meaning in Life in Late-Stage Parkinson’s Disease: Results from the Care of Late-Stage Parkinsonism Study (CLaSP) in Six European Countries
Authors: Bublitz Sarah K. , Brandstötter Cornelia , Fegg Martin , Ferreira Joaquim J. , Odin Per , Bloem Bastiaan R. , Meissner Wassilios G. , Dodel Richard , Schrag Anette , Lorenzl Stefan 
Published: December 2023

AbstractThe Care of Late-Stage Parkinsonism (CLaSP) study is a longitudinal, multicentre, prospective cohort study to assess the needs and provision of care for people with late-stage Parkinson’s disease and their caregivers in six European countries. As a cross-sectional study within the CLaSP study, 509 people with Parkinson’s disease completed the “Schedule-for-Meaning-in-Life-Evaluation” (SMiLE) questionnaire. We compared the results to those of a representative sample of healthy participants (n = 856). People with late-stage Parkinson’s disease reported family, partnership and spirituality as the greatest areas of importance. Overall, they had lower SMiLE indices compared to healthy participants. People with late-stage Parkinson’s disease rated the importance of core meaning in life areas (namely family, social relations and health) as significantly lower than the representative cohort and they also rated satisfaction as significantly lower in most areas. In conclusion, people with late-stage Parkinson’s disease do have areas where they can find meaning, such as family, partnership and spirituality. However, they indicate a lack of fulfilment of their individual MiL, reflected by low satisfaction rates in the majority of meaning in life categories. The need for spiritual support for people with Parkinson’s disease indicates the important role of chaplains to help people with Parkinson’s disease maintain meaning in life.
Origin and Evolution of Jupiter’s Trojan Asteroids
Authors: Bottke William F. , Marschall Raphael , Nesvorný David , Vokrouhlický David 
Published: December 2023

AbstractThe origin of the Jupiter Trojan asteroids has long been a mystery. Dynamically, the population, which is considerably smaller than the main asteroid belt, librates around Jupiter’s stable L4 and L5 Lagrange points, 60 deg ahead and behind Jupiter. It is thought that these bodies were captured into these orbits early in solar system history, but any capture mechanism must also explain why the Trojans have an excited inclination distribution, with some objects reaching inclinations of 35°. The Trojans themselves, individually and in aggregate, also have spectral and physical properties that appear consistent with many small bodies found in the outer solar system (e.g., irregular satellites, Kuiper belt objects). In this review, we assemble what is known about the Trojans and discuss various models for their origin and collisional evolution. It can be argued that the Trojans are unlikely to be captured planetesimals from the giant planet zone, but instead were once denizens of the primordial Kuiper belt, trapped by the events taking place during a giant planet instability. The Lucy mission to the Trojans is therefore well positioned to not only answer questions about these objects, but also about their place in planet formation and solar system evolution studies.
Social Enterprises Within the Public Sector’s Purview: A Taxonomy-Based Study on South Korea
Authors: Claassen Casper Hendrik , Mair Johanna , Bidet Eric 
Published: December 2023

AbstractThis study applies a hierarchical clustering approach to identify social enterprise models that have appeared in a setting of public sector-led incubation. Within such a context, a high degree of conformity ought to be apparent due to the coercive isomorphic pressures associated with public sector patronage. We nominate South Korea for our analysis, given that the rising number of social enterprises in the country is closely related to a regulatory intervention. Based on an analysis of 468 social enterprises, we find, contrary to expectations, that distinct clusters of government-certified social enterprises have emerged, namely social utility niche, job outsourcing, market opportunity, and integrated balanced models. We typologize these models according to their strategic orientation, mission focus, and institutional alignment. In doing so, we contribute to social enterprise research by illustrating how organizational pluralism may manifest when the growth of a population of social enterprises is directly linked to public sector intervention and regulation.
Temporal variation of allergenic potential in urban parks during the vegetation period: a case study from Bratislava, Slovakia
Authors: Zahradníková Eva , Rendeková Alena , Ščevková Jana 
Published: December 2023

AbstractPark greenery represents an oasis for urban residents; however, during the flowering period of trees that produce allergenic pollen grains, these areas threaten individuals suffering from seasonal allergic respiratory diseases. In this study, we evaluated the temporal distribution of the allergenic potential of three most important urban parks in Bratislava over the vegetation period, using a modification of the Urban Green Zone Allergenicity Index (IUGZA) and Individual-Specific Allergenic Potential Index (IISA) designed as a running index — rIUGZA and rIISA. We found that rIUGZA gives better information for park management and revitalization, since it considers the potential size of woody plants, while rIISA, considering the actual size of the vegetation, provides more relevant information for pollen-allergy sufferers. Based on rIISA, the allergenic potential was highest in May for the Grassalkovich Garden (formal baroque garden) and Janko Kráľ Park (English landscape park) and in April for the Medic Garden (repurposed baroque garden). We also found differences in the duration of the period of increased allergenic potential in these parks, ranging from 1 to 3 months. Based on the total annual sums of rIISA, we found the highest allergenic potential in the Medic Garden and lowest in the Janko Kráľ Park. This variance is caused mainly by the different density of trees and percentage of allergenic species. The biggest contributors to the allergenic potential were Platanus, Acer and Tilia. Based on the information on temporal variation of the allergenic potential during the vegetation period provided by the running indices, it is possible to improve the planning of park revitalization based on the flowering period of allergenic species and provide better information to the pollen-allergy sufferers for minimizing the allergenic effect of urban green areas on their health during a particular month.
Comparative life cycle assessment of traditional timber jack arch slab refurbishment solutions: Eco-efficient proposal versus conventional ones
Authors: Sánchez-Burgos M. A. , Pedreño-Rojas M. A. , Pérez-Gálvez F. , Rubio-de-Hita P. 
Published: December 2023

Abstract
Purpose
In the context of worldwide efforts to reduce plastic waste, the authors of this document patented a cement mortar floor slab interjoist prefab vault incorporating recycled plastic. This piece was designed to be used for the refurbishment of Spanish traditional timber jack arch floor slabs. Taking into account nowadays context, it is essential to assess the environmental benefits of this product.

Methods
A cradle to gate LCA has been performed following ISO 14044 and ISO 15804 recommendations. Thus, the aim of this research is both to provide a measure of the environmental improvement that this material adds to the building process and to compare it with current most used construction elements used for the same function. It is stressed that this study is based mainly on primary data obtained from Spanish producers.

Results
The results obtained show that the reference scenario, corresponding to the new patented vault, is the system with lower impacts in six out of the seven categories assessed. Furthermore, when adding the LCA normalisation step, the conducted analysis show that for the most influential impact categories, GWP100a and AD fossil fuels, the reference scenario bears the lowest scores.

Conclusions
It can be concluded that the new patented vault has a better environmental performance than the assessed commercial vaults. Therefore, in this research, the benefits for the construction sector to incorporate recycled plastics are shown. Furthermore, these results can encourage the research on construction products that include recycled plastics in their composition. Bearing in mind that this study assesses the impacts corresponding to the production of a prototype of the newly vault, it is considered that there is room for further improvement through the optimisation of the production process.
Awareness of Heightened Sexual and Behavioral Vulnerability as a Trigger for PrEP Resumption Among Adolescent Girls and Young Women in East and Southern Africa
Authors: Reddy Krishnaveni , Palanee-Phillips Thesla , Heffron Renee 
Published: December 2023

AbstractPurpose of ReviewEast and Southern Africa are the epicenter of the HIV epidemic. High HIV incidence rates among adolescent girls and young women (AGYW) remain stable over the last decade despite access to daily oral PrEP. Some settings have experienced high PrEP uptake among AGYW; however, discontinuation has been high. This review sought to understand drivers of PrEP discontinuation in this population in order to identify potential mechanisms to facilitate PrEP restart and optimize PrEP use.Recent FindingsDrivers of PrEP discontinuation included low perceived HIV acquisition risk, PrEP-associated side effects, pill burden, family/sexual partner disapproval, lack of/intermittent sexual activity, PrEP use stigma, fear of intimate partner violence, misinformation about long-term PrEP use, and limited/inconsistent access to PrEP.SummaryThe most frequently reported driver of PrEP discontinuation was low perceived HIV acquisition risk. This indicates that innovative interventions to help AGYW recognize their HIV risk and make informed decisions about PrEP use are urgently needed.
Role of IFN-α in Rheumatoid Arthritis
Authors: Lin Chung M. A. , Isaacs John D. , Cooles Faye A. H. 
Published: December 2023

Abstract
Purpose of Review
Type 1 interferons (IFN-I) are of increasing interest across a wide range of autoimmune rheumatic diseases. Historically, research into their role in rheumatoid arthritis (RA) has been relatively neglected, but recent work continues to highlight a potential contribution to RA pathophysiology.

Recent Findings
We emphasise the importance of disease stage when examining IFN-I in RA and provide an overview on how IFN-I may have a direct role on a variety of relevant cellular functions. We explore how clinical trajectory may be influenced by increased IFN-I signalling, and also, the limitations of scores composed of interferon response genes. Relevant environmental triggers and inheritable RA genetic risk relating to IFN-I signalling are explored with emphasis on intriguing data potentially linking IFN-I exposure, epigenetic changes, and disease relevant processes.

Summary
Whilst these data cumulatively illustrate a likely role for IFN-I in RA, they also highlight the knowledge gaps, particularly in populations at risk for RA, and suggest directions for future research to both better understand IFN-I biology and inform targeted therapeutic strategies.
Pedagogical Orientations and Evolving Responsibilities of Technological Universities: A Literature Review of the History of Engineering Education
Authors: Martin Diana Adela , Bombaerts Gunter , Horst Maja , Papageorgiou Kyriaki , Viscusi Gianluigi 
Published: December 2023

AbstractCurrent societal changes and challenges demand a broader role of technological universities, thus opening the question of how their role evolved over time and how to frame their current responsibility. In response to urgent calls for debating and redefining the identity of contemporary technological universities, this paper has two aims. The first aim is to identify the key characteristics and orientations marking the development of technological universities, as recorded in the history of engineering education. The second aim is to articulate the responsibility of contemporary technological universities given their different orientations and characteristics. For this, we first provide a non-systematic literature review of the key pedagogical orientations of technological universities, grounded in the history of engineering education. The five major orientations of technological universities presented in the paper are technical, economic, social, political, and ecological. We then use this historical survey to articulate the responsibilities of contemporary technological universities reflecting the different orientations. Technological universities can promote and foster the development of scientific, professional, civic, legal, or intra- and inter- generational responsibility. We argue that responsibility is not specific to any particular orientation, such that the concept is broadened to complement each orientation or mix of orientations of a technological university. Our contribution thus serves as a call for technological universities to self-reflect on their mission and identity, by offering a lens for identifying the orientations they currently foster and making explicit the responsibility arising from their current orientation or the ones they strive to cultivate.
Cancer of unknown primary—state of the art
Authors: Fuereder Thorsten 
Published: December 2023

SummaryThe Cancer of Unknown Primary (CUP) syndrome does not represent a single clinical entity but comprises a diverse group of malignant tumors. CUP is defined as a histologically confirmed metastatic malignant disease for which the primary tumor cannot be identified after completing initial diagnostics. Although its incidence has decreased, managing CUP patients remains a significant clinical challenge, particularly for those in the poor prognosis group, where the overall survival is merely 3 months. In this context, accurate diagnostics and prompt treatment initiation are crucial. While platinum-based chemotherapy still plays a central role in CUP therapy, the future holds promise with the advent of next-generation targeted therapies and immunotherapies guided by the results of advanced sequencing tools. These advancements offer hope for improving the bleak outcomes faced by these patients.
Moffuly-II: A Robot that Hugs and Rubs Heads
Authors: Onishi Yuya , Sumioka Hidenobu , Shiomi Masahiro 
Published: December 2023

AbstractAlthough whole-body touch interaction, e.g., hugging, is essential for human beings from various perspectives, not everyone can interact with intimate friends/family due to physical separations caused by such circumstances as pandemics, geographical constraints, etc. The possibility of human–robot touch interaction is one approach that ameliorates such missing touch interactions. In this study, we developed a robot named Moffuly-II, that hugs people and rubs their heads during a hug because head-touching behaviors are typical affective interactions between intimate persons. Moffuly-II is a large huggable teddy-bear type robot and it has enough capability to both hug and touch the head. We conducted an experiment with human participants and evaluated the effectiveness of combining intra-hug gestures (squeezing and rubbing) and the touch area (back and head). From experimental results, we identified the advantages of implementing rubbing gestures compared to squeezing gestures and some of the advantages of head-touching behaviors compared to back-touching behaviors.
Who earns trust in online environments? A meta-analysis of trust in technology and trust in provider for technology acceptance
Authors: Kuen Leonie , Westmattelmann Daniel , Bruckes Maike , Schewe Gerhard 
Published: December 2023

AbstractTrust has been identified as inevitable for technology acceptance and might further gain importance as technologies become increasingly complex. However, previous research on trust in online environments lacks a systematic configuration of trust entities in research models; some studies include either trust in technology or trust in provider, others both. In combination with inconsistent results, this leads to a lack of in-depth knowledge about the trust entities’ relationship to each other, to their antecedents, and intention to use. Therefore, this study aims at clarifying these relationships and examining how they vary for different configurations. We performed pairwise meta-analyses to generate summary effects for the individual trust entities and examined four different trust configurations by applying meta-analytic structural equation modeling (MASEM). Our findings advance technology acceptance and trust research and highlight the necessity to carefully configure trust. More specifically, the results from pairwise meta-analysis support a strong relationship between the trust entities that is, however, countered by the effects of antecedents in MASEM. Institution-based trust and reputation are found stronger predictors for trust in provider and familiarity a stronger determinant of trust in technology. Furthermore, the trust entities show comparable paths to intention to use when either trust entity is included in the research model, but when both are integrated, trust in technology is more important than trust in provider.
Sensitivity Evaluation of Enveloped and Non-enveloped Viruses to Ethanol Using Machine Learning: A Systematic Review
Authors: Wanguyun Aken Puti , Oishi Wakana , Sano Daisuke 
Published: December 2023

AbstractViral diseases are a severe public health issue worldwide. During the coronavirus pandemic, the use of alcohol-based sanitizers was recommended by WHO. Enveloped viruses are sensitive to ethanol, whereas non-enveloped viruses are considerably less sensitive. However, no quantitative analysis has been conducted to determine virus ethanol sensitivity and the important variables influencing the inactivation of viruses to ethanol. This study aimed to determine viruses’ sensitivity to ethanol and the most important variables influencing the inactivation of viruses exposed to ethanol based on machine learning. We examined 37 peer-reviewed articles through a systematic search. Quantitative analysis was employed using a decision tree and random forest algorithms. Based on the decision tree, enveloped viruses required around ≥ 35% ethanol with an average contact time of at least 1 min, which reduced the average viral load by 4 log10. In non-enveloped viruses with and without organic matter, ≥ 77.50% and ≥ 65% ethanol with an extended contact time of ≥ 2 min were required for a 4 log10 viral reduction, respectively. Important variables were assessed using a random forest based on the percentage increases in mean square error (%IncMSE) and node purity (%IncNodePurity). Ethanol concentration was a more important variable with a higher %IncMSE and %IncNodePurity than contact time for the inactivation of enveloped and non-enveloped viruses with the available organic matter. Because specific guidelines for virus inactivation by ethanol are lacking, data analysis using machine learning is essential to gain insight from certain datasets. We provide new knowledge for determining guideline values related to the selection of ethanol concentration and contact time that effectively inactivate viruses.