bluuebunny/crossref_metadata_2025_split huggingface dataset:
Trilobite body patterning and the evolution of arthropod tagmosis
Authors: Hughes Nigel C. 
Published: March 2003

AbstractPreservation permitting patterns of developmental evolution can be reconstructed within long extinct clades, and the rich fossil record of trilobite ontogeny and phylogeny provides an unparalleled opportunity for doing so. Furthermore, knowledge of Hox gene expression patterns among living arthropods permit inferences about possible Hox gene deployment in trilobites. The trilobite anteroposterior body plan is consistent with recent suggestions that basal euarthropods had a relatively low degree of tagmosis among cephalic limbs, possibly related to overlapping expression domains of cephalic Hox genes. Trilobite trunk segments appeared sequentially at a subterminal generative zone, and were exchanged between regions of fused and freely articulating segments during growth. Homonomous trunk segment shape and gradual size transition were apparently phylogenetically basal conditions and suggest a single trunk tagma. Several derived clades independently evolved functionally distinct tagmata within the trunk, apparently exchanging flexible segment numbers for greater regionally autonomy. The trilobite trunk chronicles how different aspects of arthropod segmentation coevolved as the degree of tagmosis increased. BioEssays 25:386–395, 2003. © 2003 Wiley Periodicals, Inc.
Multicenter randomized comparison of direct vs. conventional stenting: The DIRECTO trial
Authors: Ballarino Miguel A. , Moreyra Eduardo , Damonte Aníbal , Sampaolesi Alberto , Woodfield Scott , Pacheco Guillermo , Caballero Gustavo , Picabea Eduardo , Baccaro Jorge , Tapia Luis , Lascano Esteban Ruiz 
Published: March 2003

AbstractWith conventional stenting, predilatation frequently induces dissections that require deploying stents longer than originally planned. To assess whether direct stenting is safe and may prevent dissections and reduce the length of stents implanted, we conducted a randomized study comparing direct (n = 73) and conventional (n = 78) stenting. Direct stenting was successful in 89% of cases, 11% crossed over to predilation without complications. Dissections occurred more frequently in conventional stenting group (10.3% vs. 1.4%; P = 0.034), but did not translate to a significant stent length difference (16.31 ± 7.6 vs. 15.31 ± 5.5; P = NS). Periprocedure creatine kinase elevation and number of balloons utilized were lower with direct stenting. Cathet Cardiovasc Intervent 2003;58:434–440. © 2003 Wiley‐Liss, Inc.
Preliminary experiences using X‐sizer catheter for mechanical thrombectomy of thrombus‐containing lesions during acute coronary syndromes
Authors: Kornowski Ran , Ayzenberg Oded , Halon David A. , Kusniec Fabio , Assali Abid 
Published: March 2003

AbstractThrombus‐containing lesions are frequently observed in patients with acute coronary syndromes. These lesions are prone to increased procedural risks, including distal embolization and abrupt closure of the vessel. This preliminary report evaluates if thrombus removal using a new X‐Sizer catheter could reduce thrombotic burden and optimize angioplasty results. Thrombectomy was attempted with the X‐Sizer catheter in 11 patients (age, 59 ± 10 years) undergoing coronary angioplasty with angiographic evidence of intracoronary thrombus. The device uses a helix cutter contained in a 4.5 or 5.5 Fr catheter tip connected to a closed vacuum aspiration system. Procedural outcomes using detailed angiographic analysis and clinical data were obtained from all treated patients. Seven patients (64%) had acute or recent myocardial infarction and four patients (36%) presented with unstable angina. The culprit lesion was located in right coronary, left anterior, vein graft, and circumflex‐marginal in five, three, two, and one patient, respectively. The mean proximal reference diameter was 3.37 ± 0.39 mm and % diameter stenosis was 90% ± 15% prior to thrombectomy and decreased to 72% ± 16% afterward and was 9% ± 10% at the end of the procedure. The TIMI flow increased from 0.8 ± 1.0 to 2.1 ± 0.9 following thrombectomy and the final TIMI grade was 2.9 ± 0.3. Stents were used in 9 of 11 patients. Procedural success was achieved in 10 of 11 patients (91%). No evidence of stent thrombosis was noted among treated patients in hospital and at 30‐day follow‐up. In this preliminary series of patients with angiographic evidence of thrombus, the use of X‐Sizer thrombectomy seems to be feasible and relatively safe, permitting thrombus removal and improved intracoronary flow. Cathet Cardiovasc Intervent 2003;58:443–448. © 2003 Wiley‐Liss, Inc.
Stent angioplasty of severe atherosclerotic ostial renal artery stenosis in patients with diabetes mellitus and nephrosclerosis
Authors: Zeller Thomas , Müller Christian , Frank Ulrich , Bürgelin Karlheinz , Horn Barbara , Schwarzwälder Uwe , Cook‐Bruns Nancy , Neumann Franz‐Josef 
Published: March 2003

AbstractAtherosclerotic renal artery stenosis (ARAS) may lead to deterioration of renal function or hypertension. The clinical outcome after stent angioplasty of ARAS on renal function and blood pressure control in patients with diabetes and nephrosclerosis is the subject of some controversy. We have analyzed the results of our single‐center experience with stent angioplasty for severe (≥ 70%) ostial ARAS and present here the results of a subgroup analysis of those patients who had diabetes mellitus and nephrosclerosis. From 1996 to 2001, 241 patients underwent stent angioplasty for the treatment of ARAS at our center. Of these, 99 patients had diabetes mellitus (41%) and 176 patients (73%) had nephrosclerosis defined as intrarenal resistance index (RI) ≥ 0.7 diagnosed by duplex ultrasound. All lesions (n = 355) were treated successfully. Mean blood pressure at baseline was comparable and significantly improved immediately after the intervention in all groups (nondiabetics: 102 ± 12 to 93 ± 10 mm Hg; diabetics: 102 ± 14 to 93 ± 11 mm Hg; RI < 0.7: 105 ± 13 to 95 ± 10 mm Hg; RI = 0.7–0.8: 100 ± 12 to 92 ± 10 mm Hg; RI > 0.8: 102 ± 15 to 92 ± 11 mm Hg; P < 0.0001 each). Baseline serum creatinine was not significantly lower in nondiabetics compared to diabetics (1.46 ± 0.9 vs. 1.62 ± 1.2 mg %; P < 0.05) and increased in patients with nephrosclerosis (RI < 0.7: 1.18 ± 0.6 mg %; RI = 0.7–0.8: 1.57 ± 1.1 mg %; RI > 0.8: 1.96 ± 1.6 mg %). Except for patients without nephrosclerosis who had a normal baseline creatinine, serum creatinine decreased significantly in all subgroups during follow‐up. Stent angioplasty of ARAS offers favorable acute and long‐term clinical results for the preservation of the renal function and for blood pressure control in patients with diabetes mellitus and nephrosclerosis. Cathet Cardiovasc Intervent 2003;58:510–515. © 2003 Wiley‐Liss, Inc.
Simultaneous device closure of muscular ventricular septal defect and pulmonary valve balloon dilatation
Authors: Gupta Mamtesh , Juneja Rajnish , Saxena Anita 
Published: March 2003

AbstractPercutaneous closure of ventricular septal defect and pulmonary valvuloplasty appears to be an attractive modality when compared to surgical treatment for both lesions. We report successful transcatheter closure of muscular ventricular septal defect with pulmonary valve balloon dilation performed simultaneously in a 27‐year‐old woman. Technical considerations in such a setting are being discussed. Cathet Cardiovasc Intervent 2003;58:545–547. © 2003 Wiley‐Liss, Inc.
Eversion endarterectomy complicating radial artery access for left heart catheterization
Authors: Dieter Robert S. , Akef Abdul , Wolff Mathew 
Published: March 2003

AbstractThe use of the radial artery for arterial access for left heart catheterization is gaining popularity. We report the first case of traumatic eversion endarterectomy following the removal of the arterial sheath after the cannulation of the radial artery. The patient has no long‐term vascular compromise of the limb and did not require surgical intervention. Cathet Cardiovasc Intervent 2003;58:478–480. © 2003 Wiley‐Liss, Inc.
Cavernous hemangioma of the foot and antecubital fossa: An alternative therapeutic option
Authors: Baptista Edward G. , Achour Hela , Boccalandro Fernando , Smalling Richard W. 
Published: March 2003

AbstractWe present two cases of recurrent cavernous hemangiomas of the extremities. These conditions were initially treated unsuccessfully with surgical resection. After recurrence, the hemangiomas were treated by percutaneous transcatheter embolization. To the best of our knowledge, this is the first case report of treatment of cavernous hemangioma involving the extremities using an angiographically directed vascular embolization technique. Cathet Cardiovasc Intervent 2003;58:527–531. © 2003 Wiley‐Liss, Inc.
Late thrombosis after gamma‐brachytherapy
Authors: Maehara Akiko , Mintz Gary S. , Weissman Neil J. , Bui Anh B. , Castagna Marco T. , Ajani Andrew E. , Pichard August D. , Satler Lowell F. , Suddath William O. , Kent Kenneth M. , Yang Nathan , Chan Rosanna , White Larry , Waksman Ron 
Published: March 2003

AbstractLate stent thrombosis (> 30 days after treatment) is a new phenomenon occurring after vascular brachytherapy. We report the analysis of 11 patients with late thrombosis after gamma‐irradiation treatment of in‐stent restenosis. All patients had in‐stent restenosis and angina. Contributing factors to late thrombosis include long stents, small distal vessels, and complex lesion morphology. Cathet Cardiovasc Intervent 2003;58:455–458. © 2003 Wiley‐Liss, Inc.
Acute stent thrombosis after early withdrawal of platelet glycoprotein IIb/IIIa antagonists: Potential rebound prothrombotic effect?
Authors: Angiolillo Dominick Joseph , Sabaté Manel , Fernández‐Ortiz Antonio , Macaya Carlos 
Published: March 2003

AbstractWe report on two cases of acute coronary stent thrombosis after early withdrawal of different competitive inhibitors of the platelet glycoprotein IIb/IIIa receptor, eptifibatide and tirofiban. Differences in pharmacokinetics between different types of glycoprotein IIb/IIIa receptor blockers and a potential rebound prothrombotic effect with the use of these antiplatelet drugs are reviewed. Cathet Cardiovasc Intervent 2003;58:481–484. © 2003 Wiley‐Liss, Inc.
Impact of restenosis and disease progression on clinical outcome after multivessel stenting in diabetic patients
Authors: Loutfi Mohamed , Mulvihill Niall T. , Boccalatte Marco , Farah Bruno , Fajadet Jean , Marco Jean 
Published: March 2003

AbstractClinical outcome after percutaneous coronary intervention (PCI) is significantly worse in diabetic patients in comparison to nondiabetic patients. The subset of diabetic patients in the ARTS trial treated with multivessel stenting had the lowest 1‐year event‐free survival. We examined our experience of multivessel PCI in diabetics to assess clinical outcome outside clinical trials and to determine if repeat revascularizations are the result of restenosis or the progression of nontreated disease. Between January 2000 and December 2001, we performed multivessel PCI in 99 diabetic patients. Our group was well matched with those in the ARTS trial, with mean age of 69 ± 8 years, male sex 70%, hypertension 68%, hypercholesterolemia 51%, and mean LV ejection fraction 60%. The mean number of diseased segments treated was 2.8 ± 0.9 and 56% of the patients had three‐vessel disease. There were 2.3 ± 0.6 stents implanted per patient. Target vessels included the LAD in 90%, LCx in 77%, and the RCA in 87% of cases. The in‐hospital MACE rate was 8%, which included eight nonfatal MI but no deaths or repeat revascularizations. After a mean follow‐up of 14 ± 8 months, there were 4 deaths (4%), no further MIs, and 21 (21%) repeat revascularizations (2 CABG; 19 PCI), giving a 1‐year event‐free survival of 67%. There were 18 repeat revascularizations (2 CABG; 16 PCI) for restenosis, but in 9 of the 18 (50%) patients treatment was also required for progression of disease. Three further patients had PCI for symptomatic disease progression without restenosis. Thus, disease progression contributed to 57% of repeat revascularization procedures. The medium‐ and longer‐term success of multivessel PCI in diabetic patients is limited principally by the need for repeat revascularization. However, it is important to realize that these revascularizations are performed not only for restenosis but also for disease progression in more than 50% of patients. Consequently, even if drug‐eluting stent technology can eliminate restenosis, disease progression will continue to impact the clinical outcome of diabetic patients after PCI. Cathet Cardiovasc Intervent 2003;58: 451–454. © 2003 Wiley‐Liss, Inc.
Thrombin injection for treatment of false aneurysms after failed compression therapy in patients on full‐dose antiplatelet and heparin therapy
Authors: Görge Günter , Kunz Thomas 
Published: March 2003

AbstractThe aim of this study was to gauge the effectiveness of thrombin injection after failed manual compression in patients with false aneurysms receiving full‐dose antiplatelet and heparin therapy. In consecutive patients with failed manual compression therapy (ultrasound‐guided manual compression, compression bandage, or both), thrombin was injected under ultrasound guidance. In 23 patients, thrombin was injected into the false aneurysm (100–2,000 units; mean, 895 ± 520 units). All patients were on aspirin (median dose, 100 mg/day), clopidogrel (median dose, 75 mg/day), and either heparin (n = 3) with a partial thromboplastin time (PTT) > 55 sec or weight‐adjusted enoxaparine (0.1 ml per 10 kg; maximum, 1 ml/b.i.d.). Twelve patients had received an i.v. GB IIIb/IIa antagonist 11–72 hr prior to diagnosis of the aneurysm. The mean width of the false aneurysms was 20.8 ± 3.2 mm (range, 8.0–52.0 mm), length 29.7 ± 32.6 mm (range, 9.0–147 mm), and depth 19 ± 9.1 mm (range, 5.1–35.5 mm). Thrombosis after thrombin injection occurred in 21 patients within seconds. One patient required a second injection the next day, one patient underwent surgery. Overall success rate was 96%. No in‐hospital complications occurred. In patients with false aneurysms and failed compression therapy under full‐dose aspirin, clopidogrel, and heparin, selective thrombin injection is highly effective and safe. Cathet Cardiovasc Intervent 2003;58:505–509. © 2003 Wiley‐Liss, Inc.
Transthoracic left ventricular puncture for the assessment of patients with aortic and mitral valve prostheses: The Massachusetts General Hospital experience, 1989–2000
Authors: Walters Darren L. , Sanchez Pedro L. , Rodriguez‐Alemparte Maximo , Colon‐Hernandez Pedro J. , Hourigan Lisa A. , Palacios Igor F. 
Published: March 2003

AbstractAccurate assessment of suspected prosthetic valve dysfunction is critically important as reoperation carries high risk. Noninvasive methods of hemodynamic assessment of patients with both aortic and mitral mechanical valves continue to be frustrated by the interference created by prosthetic material and direct left ventricular puncture may be required for definitive hemodynamic assessment. We report the hemodynamic and angiographic results and outcomes of 38 consecutive patients with double valve replacement who underwent left ventricular puncture as part of evaluation of possible prosthetic dysfunction. These results were compared with those obtained by noninvasive testing. We found noninvasive assessment alone to be unsatisfactory as measurements of regurgitation and stenosis correlated poorly with those obtained by direct left ventricular puncture. Important information that altered patient management was obtained from invasive assessment in 68% of cases with an acceptable rate of complications. Therefore, hemodynamic and angiographic assessment using transthoracic left ventricular puncture should be entertained in patients with mitral and aortic valve replacement presenting with congestive heart failure and suspected prosthesis dysfunction. Cathet Cardiovasc Intervent 2003;58:539–544. © 2003 Wiley‐Liss, Inc.
Partial anomalous pulmonary venous return: Case report and review of the literature
Authors: AboulHosn Jamil Anis , Criley John Michael , Stringer William W. 
Published: March 2003

AbstractIsolated partial anomalous pulmonary venous return (APVR) is an uncommon finding. A patient with isolated APVR had pulmonary hypertension without demonstrable left‐to‐right shunting prior to anticoagulant treatment of pulmonary emboli. After anticoagulant therapy, with a fall in pulmonary pressures and resistance to near‐normal levels, left‐to‐right shunting was then detected by oximetry and angiography. The anomaly was visualized on electron beam angiography and confirmed by conventional angiography after anticoagulant therapy. Contrary to the expected obligatory drainage of highly saturated blood associated with APVR, lack of detectable shunting was thought to be due to the obstruction of regional blood due to thromboembolism. Cathet Cardiovasc Intervent 2003;58:548–552. © 2003 Wiley‐Liss, Inc.
Mediastinal and neck hematoma after cardiac catheterization
Authors: Jao Yeun Tarl Fresner Ng , Chen Yi , Fang Ching‐Chang , Wang Shih‐Pu 
Published: March 2003

AbstractVascular complications after cardiac catheterization are rare and usually occur at the access sites. However, vessels along the tract of the catheter can also be injured, causing bleeding and hematoma formation. We present a 57‐year‐old male who underwent cardiac catheterization via the radial approach, later developing neck and mediastinal hematoma, which was managed conservatively. This complication has only been reported once in the English literature. Cathet Cardiovasc Intervent 2003;58:467–472. © 2003 Wiley‐Liss, Inc.
Intracoronary fracture and embolization of a coronary angioplasty balloon catheter: Retrieval by a simple technique
Authors: Trehan Vijay , Mukhopadhyay Saibal , Yusuf Jamal , C. Ramgasetty Umamahesh , Mukherjee Samanjoy , Arora Ramesh 
Published: March 2003

AbstractWe report a technique for retrieval of a balloon along with a portion of its shaft from the coronary system using a simple technique that does not involve the use of snare or any other retrieval tool. An additional angioplasty wire and a balloon catheter were used to remove the balloon from the coronary system. Cathet Cardiovasc Intervent 2003;58:473–477. © 2003 Wiley‐Liss, Inc.
Coronary stenting in stable patients: Identification of a low‐risk subgroup that may not require adjunctive antiplatelet therapy
Authors: Mann Tift , Cubeddu Roberto J. , Raynor Laura , Bowen Josie , Schneider Joel E. , Rose Gregory , Cubeddu Gabriela , Ali Raza Jaffar , Jobe Robert Lee , Newman William , Zellinger Micheal 
Published: March 2003

AbstractThe present study prospectively evaluated adjunctive antiplatelet therapy in patients without insulin‐requiring diabetes during elective coronary stenting. Three hundred patients were randomized to one of three treatment groups: clopidogrel pretreatment, adjunctive abciximab, or control. Stenting was successful in 98% and no deaths occurred. Thirty‐day and 1‐year major adverse coronary events (MACEs) was similar in all groups. A subgroup of 109 patients undergoing single‐vessel stenting of type A/B1 lesions with short guidewire times had no postprocedure myocardial infarction or 30‐day MACE. We conclude that patients with these characteristics may safely undergo elective coronary stenting without adjunctive antiplatelet therapy. Cathet Cardiovasc Intervent 2003;58: 459–466. © 2003 Wiley‐Liss, Inc.
Carotid sinus reactions during carotid artery stenting: Predictors, incidence, and influence on clinical outcome
Authors: Leisch Franz , Kerschner Klaus , Hofmann Robert , Steinwender Clemens , Grund Michael , Bibl Dietmar , Leisch Franz A. , Bergmann Hans 
Published: March 2003

AbstractCarotid sinus reactions (CSR), defined as asystole ≥ 3 sec and hypotension (systolic blood pressure ≤ 90 mm Hg), are frequent events during carotid artery stenting (CAS). Factors predisposing a patient to CSR as well as the impact of CSR on periprocedural complications have not yet been investigated in a prospective manner. The relationship between various clinical, morphologic, and procedural variables and the occurrence of CSR was examined among 105 consecutive patients undergoing successful CAS. After predilatation with a compliant balloon, tubular‐slotted stents were used in all patients. No CSR occurred in 63 (60%) patients, whereas CSR developed in 42 (40%) patients. The most common type of CSR was asystole in combination with short‐term hypotension without clinical symptoms. The most important predictor of CSR was bifurcation location of carotid stenosis (bifurcation > ostial > isolated internal carotid artery; P < 0.001). The other independent predictors were presence of contralateral stenosis (P < 0.02), length of stenosis (P < 0.03), and balloon‐to‐artery ratio (P < 0.02). Occurrence of CSR was unrelated to periprocedural cerebral or cardiovascular complications (7.1% vs. 9.5%; NS). We conclude that CSR occurs frequently (40%) during CAS. Bifurcation location of stenosis is the most important predictor of CSR. CSR does not increase the risk of periprocedural complications. Cathet Cardiovasc Intervent 2003;58:516–523. © 2003 Wiley‐Liss, Inc.
Cutting balloon angioplasty for undilatable venous stenoses causing dialysis graft failure
Authors: Bittl John A. , Feldman Robert L. 
Published: March 2003

AbstractDialysis fistulas and bridge grafts frequently develop outflow stenoses in the venous limb, leading to graft failure. The venous stenoses are fibrotic and require percutaneous transluminal angioplasty with high‐pressure balloons. We have encountered venous stenoses in 3 out of 219 hemodialysis patients with graft failure that were undilatable with 6–8 mm high‐pressure balloons inflated to more than 24 atm. In each of these cases, treatment with a 4 mm cutting balloon successfully facilitated subsequent balloon dilation at lower pressures. Cathet Cardiovasc Intervent 2003;58:524–526. © 2003 Wiley‐Liss, Inc.
Percutaneous occlusion of femoral artery pseudoaneurysm by para‐aneurysmal saline injection
Authors: Gehling Gisbert , Ludwig Joseph , Schmidt Andrej , Daniel Werner G. , Werner Dierk 
Published: March 2003

AbstractThe increasing number of coronary interventions and more aggressive anticoagulation is associated with a larger number of iatrogenic femoral pseudoaneurysms (PAs). The majority of PAs clot spontaneously or can be repaired by ultrasound‐guided compression or ultrasound‐guided thrombin injection. The therapeutic armamentarium for the remaining PAs ranges from different interventional procedures to surgical occlusion. In a small case series, we describe our initial experiences with a new, less invasive approach after unsuccessful compression therapy. Ultrasound‐guided injection of 52 ± 33 ml saline beneath the communication tract of the PA yields to rapid occlusion in six consecutive patients. During 4 weeks of follow‐up, the PAs remained occluded in all patients and surgical intervention could be avoided. Cathet Cardiovasc Intervent 2003;58:500–504. © 2003 Wiley‐Liss, Inc.