bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimization of leading sectors and regional independence in the arek region, east java
Authors: Abdillah K , Edi A S , Aminatuzzuhro  
Published: January 2025

Abstract
Regional economic development focused on individual activities and analyzed the potential of regional income in diverse areas to formulate policies that encouraged faster economic growth. This study aimed to determine how economic potential and the degree of regional independence affected the economy in the Arek Region of East Java Province. A quantitative descriptive approach was used, employing secondary data from Statistics of East Java Province (BPS) with analyses of Location Quotient (LQ), degree of fiscal decentralization, and fiscal capacity index. The study concluded that there were 79 leading sectors, with Batu City having the highest average LQ of 12.10 in other service activities. The degree of fiscal decentralization indicated that 7 regions were classified as having deficient financial capacity, while 3 regions were classified as having low financial capacity. One region classified as having medium financial capacity was Surabaya City, with a score of 0.61. The fiscal capacity index calculation results revealed that 5 regions were classified as having very high fiscal capacity, 1 region as having high fiscal capacity, 3 regions as having medium fiscal capacity, and 2 regions with low fiscal capacity levels. Surabaya City had the highest fiscal capacity index at 6.65. Regions with leading sectors had the potential to improve the regional economy and increase regional independence through taxes generated from the currently developing business sector.
Financial satisfaction and financial management behavior: analysis of MSME’s coastal tourism sector
Authors: Gitayuda M B S , Purnamawati  
Published: January 2025

Abstract
This research sought to examine the effect of financial management practices on the financial satisfaction of MSMEs engaged in coastal tourism and to determine the determinants of financial satisfaction among these enterprises. A quantitative research approach was employed, utilizing descriptive and associative methods to illustrate the relationships between the studied variables. The sample consisted of 60 respondents representing MSMEs in Madura’s coastal tourism areas, specifically in the Pamekasan and Sumenep regencies. The independent variables comprised Financial Literacy and Financial Attitude, whilst the intervening variable was financial management behavior, with financial pleasure serving as the dependent variable. This quantitative descriptive study utilized a Likert scale to assess responses and adopted purposive sampling as its non-probability sampling technique. The analysis of data was performed via Structural Equation Modeling (SEM) and processed via SmartPLS 3.0 software. The results of the investigation were as follows: The relationship between Financial Literacy and Financial Management Behavior is positive; however, it does not have a direct impact on Financial Satisfaction. The financial attitude has a positive impact on both financial management behavior and financial satisfaction. Moreover, the behavior associated with financial management has a positive influence on financial satisfaction and serves as a mediator in the relationship between financial literacy and financial satisfaction, in addition to the relationship between financial attitude and financial satisfaction.
The influence of e-government integration and data interoperability policies on poverty reduction
Authors: Sarofah R , Ramdhani H , Firmadi S 
Published: January 2025

Abstract
This research analyzed the influence of e-government integration policies and data interoperability on poverty alleviation in Tasikmalaya City. The research was motivated by the importance of creating sustainable government governance, especially in realizing reduced poverty rates in Tasikmalaya City. One of the most appropriate approaches was service integration policy intervention. The research used a quantitative approach with survey research through data collection in questionnaires to 330 respondents using random sampling clusters spread throughout the sub-districts of Tasikmalaya City. The independent variables used were e-government policy and data interoperability. Apart from that, the dependent variable was poverty reduction. The data interoperability and e-government influenced poverty alleviation by 54.07%. On the other hand, some evidence suggested a connection between data interoperability and poverty reduction to a certain extent. This emphasized the importance of integration between agencies, which could be accessed through a collection of inter-agency activity programs, especially in the distribution of poverty assistance programs. Therefore, the Tasikmalaya City Government needed to immediately implement a data interoperability policy as a valuable effort to design economic empowerment programs and create an integrated public service online portal that provided information ranging from social assistance to workforce training programs. This service would make it easier for poor target groups to obtain accurate information as part of poverty reduction services. Some programs run by the Tasikmalaya City Government included distributing aid programs to the poor, providing information on job opportunities, and increasing information on various departmental collaboration programs.
Synergizing bioprinting and 3D cell culture to enhance tissue formation in printed synthetic constructs
Authors: Günther Daniel , Bergerbit Cédric , Marsee Ary , Vedaraman Sitara , Pueyo Moliner Alba , Bastard Céline , Eelen Guy , Gerardo Nava José Luis , Dewerchin Mieke , Carmeliet Peter , Kramann Rafael , Schneeberger Kerstin , Spee Bart , De Laporte Laura 
Published: January 2025

Abstract
Bioprinting is currently the most promising method to biofabricate complex tissues in vitro with the potential to transform the future of organ transplantation and drug discovery. Efforts to create such tissues are, however, almost exclusively based on animal-derived materials, such as gelatin methacryloyl, which have demonstrated efficacy in bioprinting of complex tissues. While these materials are already used in clinical applications, uncertainty about their safety still remains due to their animal origin. Alternatively, synthetic bioinks have been developed that match the printability of natural bioinks but lack their biological complexity, and thereby often fail to support cell growth and facilitate tissue formation. Additionally, most synthetic materials do not meet the mechanical demands of bioprint stable constructs while providing a suitable environment for cells to grow, limiting the number of available bioinks. To bridge this gap and synergize bioprinting and 3D cell culture, we developed a polyethylene glycol-based bioink system to promote the growth and spreading of cell spheroids that consist of human primary endothelial cells and fibroblasts. The 3D bioprinted centimeter-scale constructs have a high shape fidelity and accelerated softening to provide sufficient space for cells to grow. Adjusting the rate of degradability, induced by the integration of ester-functionalized crosslinkers in addition to protease cleavable crosslinkers into the hydrogel network, improves the growth of spheroids in larger printed hydrogel constructs containing an interconnected channel structure. The perfusable constructs enable extensive spheroid sprouting and the formation of a cellular network upon fusion of sprouts as initial steps toward tissue formation with the potential for clinical translation.
Study on the mechanical behavior of corroded bridge steel based on the entire process of tensile failure
Authors: Li Yi , Hu Dapeng , Xu Yangming , Wang Bo , Zhou Yongjun , Dong Zhonghong 
Published: January 2025

Abstract
The Q345qD bridge steels exposed to severe corrosion environments undergo mechanical property degradation, posing significant safety risks for sea-crossing bridges. Assessing the health of corroded bridge steel structures under load conditions in a manner that avoids causing damage can effectively prevent these intensifying safety hazards. To investigate the impact of corrosion on the mechanical performance of these steels, six sets of standard specimens underwent corrosion ranging from 0 to 896 h. Subsequently, during tensile testing, an image acquisition platform was established to utilize Digital Image Correlation (DIC) techniques for capturing and observing the tensile loading processes of various corroded specimens. Analysis of stress–strain curves and strain field evolution patterns provided insights into the deterioration of mechanical properties of Q345qD bridge steels after corrosion. For corroded bridge steel structures, defects caused by the corrosion pits can still result in localized strain concentration under low load levels. At higher load levels, mass loss due to corrosion or reduced cross-sectional dimensions of load-bearing elements are the primary causes of mechanical performance decline, precipitating overall structural failure. These findings provide some references for routine maintenance of steel structures of cross-sea bridges.
Cross-sectional survey of healthcare professionals’ perceptions of bedrails as a measure of physical restraint in the hospital setting
Authors: Gálvez-Barrón César , González-De Luna Ana , Pérez-López Carlos , Macho-Perez Oscar 
Published: January 2025

Abstract

Objective
Although bedrails are considered a restraint measure under the legal regulations in Spain, no data on the related perceptions of healthcare professionals (HCPs) are available. Thus, this study aimed to calculate the proportion of HCPs in the hospital setting that consider bedrails to be a restraint measure.

Methods
Between June and December 2022, a cross-sectional online survey was conducted among the HCPs at our institution. Basal information was collected in the first section, and seven questions related to bedrails were included in the second. The perception of bedrails as a restraint measure was evaluated with a multiple-choice question in which devices that can be considered restraint measures were listed.

Results
A total of 246 HCPs participated in the survey, 201 of whom passed quality control and were analysed. The mean age was 42.2 years old, and 85% of the participants were women.
The proportion of HCPs who considered bedrails as a restraint measure was 54.2% (95% confidence interval [CI]: 47.3–61.1) in the total group and 54.5% (95% CI: 44.1–65.0) in the intermediate care subgroup. These proportions were significantly lower for HCPs who worked night shifts and among those who believed that bedrails do not limit patient mobility.

Conclusions
There is a considerable difference between what is established in legal regulations and the perceptions of HCPs in terms of bedrails being considered a restraint measure. Our results can help improve the content of training programs on the use of restraint measures by HCPs.
Association between wine consumption and migraine: a systematic review and meta-analysis of cross-sectional
Authors: Lucerón-Lucas-Torres Maribel , Ruiz-Grao Marta C , Pascual-Morena Carlos , Priego-Jiménez Susana , López-González María , Álvarez-Bueno Celia 
Published: January 2025

Abstract

Background
It seems that diet is one of the main triggers of migraine; one of the most studied is alcohol, and also, over the years, red wine has been shown to trigger headaches. Therefore, this systematic review and meta-analysis aims to examine the strength of the association between wine consumption and migraine.

Methods
In this systematic review and meta-analysis, a search of MEDLINE (via PubMed), Scopus, Cochrane, and Web of Science databases was conducted to assess the association between wine consumption and migraine, covering baseline to December 2023. Pooled Odds Ratio (p-OR) were calculated using the DerSimonian and Laird methods. This study was previously registered in PROSPERO (CRD42024511115). The risk of bias was evaluated using The Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies.

Results
Five studies were included in this systematic review, and only four of them were in the meta-analysis. Using the DerSimonian and Laird method, the p-OR for the effect of wine consumption on migraine was 0.63 (95% CI 0.36–1.09). The included studies after the risk of bias assessment showed a moderate risk of bias.

Conclusions
The findings of this systematic review and meta-analysis indicate that there is no conclusive evidence to support an increased or decreased risk of migraine associated with wine consumption.
Overview of historical occupational exposure to trichloroethylene in China
Authors: Nie Jia , Ge Calvin B , Rothman Nathaniel , Hu Wei , Vermeulen Roel , Lan Qing , Peters Susan 
Published: January 2025

Abstract

Objectives
Trichloroethylene (TCE) is a carcinogen that has been causally linked to kidney cancer and possibly other cancer sites including the liver and lymphatic system. Its use in China has increased since the early 1990s due to the growing metal and electronic industries. We aimed to summarize the major sources of occupational exposure to TCE over time in China.

Methods
Occupational TCE exposure assessments were extracted from both the Chinese and English scientific literature, as well as from industrial hygiene surveys performed in Guangdong, Tianjin, and Hong Kong. Weighted mean concentrations were summarized by occupation and industry.

Results
We extracted over 12,412 measurements from 55 industries and 35 occupations across China since 1976, of which at least 201 were from case reports. More than half of the measurements were derived from 4 industries, including “manufacture of footwear” (29%), “manufacture of electronic components and boards” (17%), “manufacture of games and toys” (14%), and “manufacture of fabricated metal products, except machinery and equipment” (13%). Several occupations, including “electronic-equipment assemblers,” “metal-, rubber-, and plastic-products assemblers,” “metal finishing-, plating-, and coating-machine operators,” “precision-instrument makers and repairers,” “printing-machine operators,” and “ore and metal furnace operators” were identified as having high risks of TCE exposure, with either pooled weighted mean task-based or full-shift concentrations over 150 mg/m3 over the years. TCE exposure levels varied across different occupations and changed over time. In 1990 and earlier, 1991 to 2000, the exposure levels were at their highest with pooled weighted mean task-based concentrations of 202.8 and 242.9 mg/m3, respectively. Subsequently, the level decreased to 118.7 mg/m3 from 2001 to 2010 before increasing again to 216.0 mg/m3 from 2011 onwards. This overall trend was also observed for “electronic-equipment assemblers” and “metal finishing-, plating-, and coating-machine operators.” However, for “precision-instrument makers and repairers,” the exposure levels consistently declined over the years.

Conclusions
Over the past few decades, degreasing-related occupations, such as “electronic-equipment assemblers” and “metal finishing-, plating-, and coating-machine operators” have been consistently identified as being at high risk of significant TCE exposure and continued to warrant attention. Identifying high-risk industries and occupations can inform the development of targeted interventions and regulations to mitigate TCE exposure. Furthermore, enhancing the quality and coverage of exposure measurement data in occupational settings will advance epidemiological investigations in occupational health.
Daily noise dose and power tool characterization of steel stud framers on commercial construction sites
Authors: Schutt David , Lipsey Tiffany , Van Dyke Mike , Brazile William J 
Published: January 2025

Abstract
The construction industry is well-documented as having numerous sources of hazardous noise on the job. Framers who cut and install steel studs on commercial construction sites use a variety of power tools throughout the course of their normal workday and have the potential to be exposed to levels of noise that can lead to occupational noise-induced hearing loss. This study assessed the noise dose of commercial steel stud framers and characterized the noise of common power tools that contribute to their daily noise dose. Occupational exposure limits exist in both required and recommended forms to protect workers; however, large differences in the level of worker protection are apparent between the mandated Occupational Safety and Health Administration (OSHA) permissible exposure limit (PEL) and the voluntary National Institute for Occupational Safety and Health (NIOSH) recommended exposure limit (REL) for noise exposure. Steel stud framers in this study had a mean OSHA PEL dose of 27.6% and a mean NIOSH REL dose of 340.7% for the same workers. As a comparison, ambient equivalent noise doses at the construction site were 1.4% for PEL criteria and 12.4% for REL criteria. Of task assignments during the workday, workers who were assigned primarily as saw operators had statistically significant higher noise exposures than workers who were assigned as stud installers (P = 0.037). Octave band analysis was conducted for full-day exposures and indicated an upward trend of higher noise exposures at higher frequencies. Overall, among all steel stud framers involved in this study, all workers had noise doses below the OSHA PEL (range 5.8% to 61.4%), and all but 2 workers (n = 35) had noise doses above the NIOSH REL (range 63.9% to 823.2%), indicating exposure to hazardous levels of noise based on more protective RELs.
Monitoring genetic diversity of Torminalis glaberrima for resilient forests in the face of population fragmentation
Authors: Afifi Lila , Szukala Aglaia , Klumpp Raphael , Tremetsberger Karin , Konrad Heino 
Published: January 2025

Abstract

Background and Aims
Torminalis glaberrima is a European tree species currently underutilized in forestry, valued for its high-quality wood and contribution to ecosystem stability. Despite a projected range expansion as climate change progresses, current population fragmentation levels may inhibit the species’ ability to migrate and stabilize fragile forest ecosystems. To investigate the relationship between structural and functional connectivity, we surveyed the genetic diversity, spatial genetic structure and gene flow of T. glaberrima across Austria, to understand which populations should be given conservation priority.

Methods
Our sampling encompasses 21 natural and planted populations and 910 individuals of T. glaberrima covering the species’ distribution in Austria. We estimated genetic diversity indices, the extent of gene dispersal, and conducted SPAGeDi and STRUCTURE analyses and discriminant analysis of principal components using one chloroplast minisatellite and eight nuclear microsatellite markers.

Key Results
Despite a highly fragmented distribution of T. glaberrima in the southern, western and central parts of its range in Austria, we found high genetic diversity and low population differentiation and inbreeding, and estimated higher gene dispersal values than previous studies. Population structure analyses identified two main regions of genetic ancestry in the north-western and south-eastern part of the species’ range in Austria and evidence for the usage of foreign genetic material in two planted populations.

Conclusions
Only two of the established ex situ plantations and seed orchards appear to well represent the fine-scale population structure present in Austria, and existing in situ gene conservation units (GCUs) are insufficient to conserve the current natural genetic diversity. We suggest the establishment of further in situ GCUs to maximize the conservation of extant forest genetic diversity. Additionally, we encourage corridor plantings between isolated populations, bolstering the genetic connectivity and diversity of populations.
Niche shifts and localized competitive dynamics influence the persistence and distribution of polyploids in the genus Achillea (Asteraceae)
Authors: Lu Wen-Xun , Tu Wen-Qin , Chen Duo , Wang Zi-Zhao , Guo Yan-Ping 
Published: January 2025

Abstract

Background and Aims
Competition with sympatric diploid progenitor(s) hinders the persistence of polyploids. The hypothesis that polyploids escape from competition through niche shifts has been widely tested; however, niche escape is unlikely to completely avoid competition. Given species growing in less favourable environments probably have weaker competitive abilities, we hypothesize that polyploid populations tend to persist in areas where their progenitors have relatively low habitat suitability.

Methods
This study investigated two sibling allopolyploid species, Achillea alpina and A. wilsoniana of the daisy family, which originated independently from the same two parental species. We explored the patterns of niche shifts between the polyploids and their progenitors by using several ecoinformatics analyses in environmental and geographical spaces, and performed ecological niche modelling to estimate the historical distribution of these species as well as the potential regions for persistence of allopolyploids.

Key Results
The niche shift patterns of the two polyploids were not completely consistent: A. alpina showed niche expansion, while A. wilsoniana exhibited a trend towards niche novelty. Their potential suitable areas were both more likely to overlap with regions where the habitat suitability values of their parental species became low.

Conclusions
The present results support our hypothesis that populations of polyploids tend to persist in areas that are less suitable for their diploid progenitors. Meanwhile, niche shifts may promote the success of polyploids. These findings contribute to our understanding of the ecological processes involved in the maintenance and persistence of polyploids.
Rosae multiflorae fructus extracts regulate the differentiation and vascular endothelial cell-mediated proliferation of keratinocytes
Authors: Asayama Sae , Igarashi Tami , Abe Yosihimi , Iwasaki Ayaka , Kubo Mizuki , Ikeda Ayaka , Akiyama Kouki , Okamoto Tadashi , Yagi Masayuki , Niki Yoko , Ando Hideya , Ichihashi Masamitsu , Mizutani Ken-ichi 
Published: January 2025

Abstract
Keratinocytes are the primary component of the epidermis, so maintaining the precise balance between proliferation and differentiation is essential for conserving epidermal structure and function. Rosae multiflorae fructus extract (RMFE) has wide application in the cosmetic industry, but the molecular mechanisms underlying beneficial effects on keratinocytes are still not fully understood. In this study, we found that RMFE promoted epidermal differentiation and enhanced the barrier function of normal human epidermal keratinocytes (NHEKs) and three-dimensional epidermis model in culture. In addition, RMFE promoted human umbilical vein endothelial cell (HUVEC) proliferation and angiogenesis, whereas the conditioned medium from RMFE-treated HUVECs further promoted NHEK proliferation and increased wound healing ability. Analysis of constituent bioactivities identified a quercetin derivative as a potential mediator of NHEK and HUVEC responses to RMFE. Taken together, these results suggest that RMFE enhances epidermal functions through both direct effects on keratinocytes and indirect effects mediated by endothelial cells.