bluuebunny/crossref_metadata_2025_split huggingface dataset:
Outcome and determinants of Directly Observed Short-course treatment for tuberculosis patients
Authors: Al-Janabi Alaa Hussein Khudhair 
Published: December 2023

Background: The Directly Observed Treatment Short Course (DOTS) is a well-established and cost-effective strategy for treating Tuberculosis. It efficiently transforms infectious cases into non infectious ones, effectively interrupting the transmission cycle of the disease. Objectives: Measure the treatment outcomes in TB patients during 2016-2020, describe the socio-demographic and clinical profile of TB patients and evaluate the performance of the National TB program in Babil governorate based on WHO indicators. Methods: A descriptive cross-sectional study was done. All TB patients in the NTP Center of Babil governorate under the DOTS program from 2016 to 2020 were included. A form was developed to compile socio-demographic data, clinical presentation, and treatment outcomes. Results: A total number of cases was 1723. The mean age was 40.0 (± 21.0) years. The female constituted 53.8% of cases. The patients aged ≥ 65 years had the highest percentage of total cases 279 (16.2%). Pulmonary tuberculosis (PTB) constituted 56.1% of the cases 50.5% of them had smear-positive. The most common site for extrapulmonary tuberculosis (EPTB) was lymph nodes 41.1%. Treatment success was attained in 93.7%, while 3.3% of patients dead. The patients aged ≥ 65 years have the lowest success rate and highest treatment unsuccess rate opposite to young age groups (p 0.002). Conclusion: The treatment outcome target planned by WHO was achieved. The case detection rate of all form was low. The age and the site of TB significantly affected the outcome of treatment.
ĐÁNH GIÁ BƯỚC ĐẦU ĐIỀU TRỊ SỎI THẬN BẰNG PHƯƠNG PHÁP TÁN SỎI ỐNG MỀM TẠI BỆNH VIỆN ĐA KHOA ĐỨC GIANG
Authors: Nguyễn Công Hiếu , Lê Nguyên Vũ 
Published: December 2023

Mục tiêu: Đánh giá kết quả bước đầu điều trị sỏi thận bằng phương pháp tán sỏi ống mềm tại bệnh viện đa khoa Đức Giang.Đối tượng và phương pháp nghiên cứu: Mô tả lâm sàng , lấy số liệu hồi cứu và tiến cứu đánh giá trên 41 bệnh nhân được chẩn đoán sỏi thận và chỉ định tán sỏi bằng nội soi ống mềm tại bệnh viện đa khoa Đức Giang từ tháng 11/2019 đến tháng 9/2021. Các biến nghiên cứu: Đặc điểm chung: Tuổi, giới, lý do vào viện, tiền sử bệnh nội khoa, tiền sử can thiệp trên thận, bạch cầu niệu và cấy nước tiểu trước mổ, mức độ ứ nước thận, số lượng và vị trí sỏi, kích thước sỏi, bệnh nhân được đặt JJ trước mổ. Kết quả điều trị: Thời gian tán sỏi trung bình, thời gian nằm viện trung bình, tỉ lệ sót sỏi trên xq sau mổ 1 ngày, diễn biến sau mổ, kết quả khám lại sau 1 tháng. Kết quả: Tỷ lệ nam/nữ: 58,5/48,5, lứa tuổi chủ yếu là trên 41 tuổi. Tuổi trung bình: 51,02 ± 13,62 (nhỏ nhất 17 tuổi, lớn nhất 75 tuổi), Tỉ lệ nữ/nam : 1,41. Bệnh nhân tới khám đa phần vì lý do đau thắt lưng do sỏi gây tắc nghẽn chiếm 65,9%. Có 8 trường hợp tái khám sau khi tán sỏi niệu quản ngược dòng chiếm 19,5%, 4 trường hợp khám sức khỏe phát hiện sỏi thận (9,8%) và một trường hợp sau can thiệp tán sỏi qua da chiếm 2,4%. Số bệnh nhân có bạch cầu niệu trước mổ được cấy nước tiểu dương tính là 3/18 trường hợp chiếm 16,7%. Đa phần các trường hợp ứ nước thận nhẹ (không ứ nước thận và ứ nước thận độ 1), chiếm 58,5%Số lượng sỏi trung bình 1,7±1,17 viên. Kích thước trung bình 16±4,89 mm (8-25mm). Nhóm sỏi kích thước dưới 20mm chiếm tỷ lệ cao 80,5%, trong đó sỏi đài thận đơn thuần chiếm tỷ lệ cao nhất (36,6%). Kết quả sạch sỏi sau 1 tháng 80,5%. Tai biến trong mổ không gặp trường hợp nào. 40/41 trường hợp tiếp cận được sỏi chiếm tỷ lệ 97,6%. Thời gian nằm viện trung bình 5,67±1,37 ngày. Kết luận: Phẫu thuật điều trị sỏi thận bằng phương pháp tán sỏi ống mềm tại bệnh viện đa khoa Đức Giang là phương pháp an toàn, hậu phẫu ngắn, tỉ lệ sạch sỏi cao, đạt kết quả tốt về lâm sàng.
Avsec Officer Service Excellent Analysis To The Security And Safety Of Aviation At The Security Check Point Of Tambolaka Airport In The New Normal Era. Study Program DIV Air Transportation Management, Bachelor level, Diploma IV Program, Yogyakarta College
Authors: Wilhelmina Florencia Koting  , Rahimudin  
Published: December 2023

Avsec officers at the Tambolaka Airport Security Check Point are the front guard who meet and directly serve air transportation service users, but Avsec officers still lack awareness of appearance because they have not used uniforms and attributes according to the provisions. This study aims to determine the effect of Avsec officers excellent service on aviation security and safety and how much influence Avsec officers' excellent service has on flight security and safety at the Tambolaka Airport Security Check Point during the new normal period.
Research using quantitative methods. Respondents' answers as primary data and data on the number of passengers in September as secondary data in the study. The population in this study were all users of air transportation services at Tambolaka Airport, while the research sample was determined from data on the number of passengers in September using the slovin formula. Data analysis performed included validity, reliability, and simple linear regression analysis
The results of this study is influence of Avsec officers' excellent service on flight security and safety at the Tambolaka Airport Security Check Point during the new normal period. This is evidenced by the t-count 15.254 > t-table 1.985 and a significant value 0.00 <0.05. The results of this study also show the value of the coefficient of determination is 0.704. This value means that the great influence exerted by Avsec officers' excellent service on flight security and safety at the Tambolaka Airport Security Check Point during the new normal period was 70.4%.
Raman lidar-derived optical and microphysical properties of ice crystals within thin Arctic clouds during PARCS campaign
Authors: Chazette Patrick , Raut Jean-Christophe 
Published: December 2023

Abstract. Cloud observations in the Arctic are still rare, which requires innovative observation techniques to assess ice crystal properties. We present an original approach using the Raman lidar measurements applied to a case study in northern Scandinavia. The vertical profiles of the optical properties, the effective radius of ice crystals and ice water content (IWC) in Arctic semi-transparent clouds were assessed using quantitative ground-based lidar measurements at 355 nm performed from 13 to 26 May 2016 in Hammerfest (north of Norway, 70∘39′48′′ N, 23∘41′00′′ E). The field campaign was part of the Pollution in the ARCtic System (PARCS) project of the French Arctic Initiative. The presence of low-level semi-transparent clouds was noted on 16 and 17 May. The cloud base was located just above the atmospheric boundary layer where the 0 ∘C isotherm reached around 800 m above the mean sea level (a.m.s.l.). To ensure the best penetration of the laser beam into the cloud, we selected case studies with cloud optical thickness (COT) lower than 2 and out of supercooled liquid pockets. Lidar-derived multiple scattering coefficients were found to be close to 1 and ice crystal depolarization around 10 %, suggesting that ice crystals were small and had a rather spherical shape. Using Mie computations, we determine effective radii between ∼7 and 25 µm in the clouds for ice water contents between 1 and 8 mg m−3, respectively. The uncertainties regarding the effective radii and ice water content are on average 2 µm and 0.65 mg m−3, respectively.
PTSD Symptom Severity and Overall Quality of Life Pre-and During COVID-19 Among Adults Seeking Housing Support Services
Authors: Crisanti Annette S. , Quazi Mohammed , Kincaid Tyler , De W Romero Anastacia , Wu Xiaoya , Bowen Neal , Altschul Deborah 
Published: December 2023

COVID-19 stay-at-home orders have had far-reaching negative consequences on mental health and quality of life (QOL). This is especially true for vulnerable populations, such as those who are unhoused, as they are more likely than the general population to have been struggling with a mental illness and poor QOL well before the pandemic. This exploratory cross-sectional study explored differences in PTSD symptom severity and overall QOL among a cohort of adults who were seeking housing support services pre-COVID-19 (n = 226 compared to a cohort of adults who were seeking housing support services during COVID-19 (n =205). All data were collected upon enrollment into a permanent supportive housing program. Participants seeking housing support services during COVID-19 compared to pre-COVID-19 were significantly more likely to report higher PTSD symptoms (t=3.14, p=0.001) and poorer QOL (=9.81, p=0.001), however differences were no longer observed at the five percent significance level once several covariates were controlled for in the analysis. Despite the lack of statistical significance at the multivariate level (which is likely a result of challenges with the data and the level of statistical significance selected and not a reflection of true differences between the cohorts), the clinical significance of the findings has implications for planning behavioral health services for unhoused individuals seeking housing support services, especially as we exit the pandemic.
Impact of employment and income support interventions on the health of young adults with episodic disability: Findings from a systematic review
Authors: Jetha Arif , Navaratnerajah Lahmea , Kondratowski Sebastian , Parmassar Meagan , Tucker Lori B , Gignac Monique AM 
Published: December 2023

OBJECTIVE: Young adults living with episodic disabilities face unpredictable disruptions to their employment and health. Our study aimed to examine the impact of employment and income support interventions on the health and well-being of young adults living with episodic disabilities.
METHODS: We conducted a systematic review of peer-reviewed intervention studies published in 2001–2021 in industrialized contexts. Two independent reviewers screened titles, abstracts and full-texts. We undertook a narrative synthesis of eligible articles.
RESULTS: Our search yielded 15 269 published articles, of which only five studies were eligible for evidence synthesis. All articles were appraised as being of medium quality. Four interventions focused on young adults living with mental health conditions. Two were based in clinical settings; three were based in community-based settings. Each employment intervention exhibited improvements in health outcomes. Three studies examined the impact of supported employment interventions that were particularly beneficial to improving work and health outcomes.
CONCLUSION: Involvement in employment interventions could provide benefits for the health of young adults living with episodic disabilities. Our systematic review highlights the need for research to elaborate on the ways in which employment interventions can impact the health and well-being of young adults living with different episodic disabilities.
Giải pháp nâng cao hiệu quả giáo dục hòa nhập cho trẻ khuyết tật tuổi mẫu giáo
Authors: Lê Thị Thanh Sang 
Published: December 2023

Giáo dục hoà nhập cho trẻ khuyết tật tuổi mẫu giáo là một nhiệm vụ mang ý nghĩa quan trọng và cần thiết. Trẻ khuyết tật tuổi mẫu giáo cũng như những trẻ em bình thường khác có quyền được học tập và vui chơi, được chăm sóc và hưởng sự giáo dục bình đẳng theo công ước bảo vệ quyền trẻ em trên toàn thế giới, trong đó có Việt Nam. Trong bài viết, chúng tôi xây dựng một số khái niệm của vấn đề nghiên cứu; trình bày một số nét tâm lý đặc trưng cơ bản của trẻ khuyết tật; vai trò của giáo dục hoà nhập đối với trẻ khuyết tật tuổi mẫu giáo; Từ đó, chúng tôi đề xuất một số giải pháp nâng cao hiệu quả giáo dục hòa nhập cho trẻ khuyết tật tuổi mẫu giáo đang được chăm sóc nuôi dưỡng và giáo dục ở trường mầm non.
Animals in Restoration Theatre, 1660–1710
Authors: Miyoshi Riki 
Published: December 2023

ABSTRACT
Performing animals in Restoration theatre have seldom been the focal point of research. Exceptions include Michael Burden’s “Dancing Monkeys at Dorset Garden,” which examined the possible use of live monkeys in Henry Purcell’s opera The Fairy-Queen (1692), and Rafael Portillo’s “Staging Restoration Dramas,” a portion of which is dedicated to animals on the stage. This article provides a survey of animals on the Restoration stage and demonstrates the survival of a meaningful amount of evidence to suggest that live animals were employed more often than has hitherto been believed. It further argues that animals made a significant contribution to theatrical productions of the Restoration period.
On transformation of the genre of the Adyghe novel about the historical past at the turn of the XX-XXI centuries
Authors: Паранук К.Н. , Зеленская К.А. 
Published: December 2023

Рассматриваются художественные особенности адыгского романа конца ХХ - нач. ХХI веков. Анализируются романы адыгских писателей Ю. Чуяко, Н. Куёка, Х. Бештокова, Д. Кошубаева в разрезе отображения трансформационных процессов, произошедших в нем на рубеже веков. Уточняются этапы развития адыгского романа в плане взаимодействия с фольклором, определяется новый характер взаимодействия с мифо-эпической традицией в романе об историческом прошлом, выявляются его интертекстуальные связи, типологические схождения с произведениями мировой литературы. Выявляются значительные трансформации жанровой формы адыгского романа об историческом прошлом, выражающиеся в зарождении и утверждении неомифологизма, приобщающие адыгский роман к лучшим достижениям мировой романистики.
The study considers artistic features of the Adyghe novel of the late 20th - early 21st centu-ry. The novels of Adyghe writers Y. Chuyako, N. Kuyok, Kh. Beshtokov and D. Koshubaev are analyzed in the context of reflecting the transformation processes that occurred at the turn of the century. The authors clarify stages of development of the Adyghe novel in terms of interaction with folklore and determine the new nature of interaction with the mytho-epic tradition in the novel about the historical past. The study reveals the intertextual connections and typological sim-ilarities with works of world literature. The authors reveal significant transformations of the genre form of the Adyghe novel about the historical past, expressed in the emergence and establishment of neo-mythologism, introducing the Adyghe novel to the best achievements of world novelism.
Crup causado por Síndrome Respiratorio Agudo Severo secundario a Coronavirus 2 (SARS-CoV-2)
Authors: Rodríguez Ana G , Velásquez Belinda , Banegas Linda , Portillo Melissa 
Published: December 2023

Antecedentes: el crup es la causa más frecuente de obstrucción aguda de la vía aérea superior en la infancia, con predominio entre los 6 meses y 3 años de edad., la mayoría de los casos son de etiología viral y presentación leve.
Descripción de caso: primer caso masculino de 9 meses previamente sano con crup asociado a SARS-COV-2 en la Unidad de Cuidados Intensivos Pediátricos (UCIP) del Instituto Hondureño de Seguridad Social - Hospital Regional del Norte (IHSS-HRN) con manifestaciones clínicas de un crup severo, quien requirió secuencia de intubación rápida, asistencia ventilatoria mecánica y manejo en la unidad de cuidados intensivos, evolucionando satisfactoriamente con el manejo clásico de crup más uso de Remdesivir.
Conclusión: al ser una enfermedad emergente es importante caracterizar las distintas cartas de presentación de esta infección en el paciente pediátrico y debe resaltarse el aislamiento de SARS- COV-2 como un causante más de estridor viral en los niños.
Clinical factors predicting rotavirus diarrhea in children: A cross-sectional study from two hospitals
Authors: Indrawan Michelle , Chendana Jason , Handoko Tan Gabriella Heidina , Widjaja Melanie , Octavius Gilbert Sterling 
Published: December 2023

BACKGROUND
Rotavirus is still a significant contributing morbidity and mortality in pediatric patients.
AIM
To look at clinical signs and symptoms and laboratory findings that can predict rotavirus gastroenteritis compared to non-rotavirus gastroenteritis.
METHODS
This was a cross-sectional study with medical records obtained from December 2015 to December 2019. Inclusion criteria for this study include all hospitalised pediatric patients (0-18 years old) diagnosed with suspected rotavirus diarrhea. The receiver operating curve and Hosmer-Lemeshow test would be used to assess the final prediction findings' calibration (goodness of fit) and discrimination performance.
RESULTS
This study included 267 participants with 187 (70%) rotavirus-diarrhea cases. The patients were primarily male in both rotavirus (65.2%) and non-rotavirus (62.5%) groups. The median age is 1.33 years old (0.08-17.67 years old). Multivariate analysis shows that wet season (ORadj = 2.5; 95%CI: 1.3-4.8, Padj = 0.006), length of stay (LOS) ≥ 3 days (ORadj = 5.1; 95%CI: 1.4-4.8, Padj = 0.015), presence of abdominal pain (ORadj = 3.0; 95%CI: 1.3-6.8, Padj = 0.007), severe dehydration (ORadj = 2.9; 95%CI: 1.1-7.9, Padj = 0.034), abnormal white blood cell counts (ORadj = 2.8; 95%CI: 1.3-6.0, Padj = 0.006), abnormal random blood glucose (ORadj = 2.3; 95%CI: 1.2-4.4, Padj = 0.018) and presence of fecal leukocytes (ORadj = 4.1, 95%CI: 1.7-9.5, Padj = 0.001) are predictors of rotavirus diarrhea. The area under the curve for this model is 0.819 (95%CI: 0.746-0.878, P value < 0.001), which shows that this model has good discrimination.
CONCLUSION
Wet season, LOS ≥ 3 d, presence of abdominal pain, severe dehydration, abnormal white blood cell counts, abnormal random blood glucose, and presence of fecal leukocytes predict rotavirus diarrhea.
Warburg effect mimicking inborn errors of metabolism in childhood hematologic malignancies: A case-based systematic review
Authors: Permtawee Khanittha , Tengsujaritkul Maliwan , Choed-Amphai Chane , Chanthong Supapitch , Mankhemthong Kanittha , Sathitsamitphong Lalita , Natesirinilkul Rungrote , Charoenkwan Pimlak 
Published: December 2023

BACKGROUND
Type B lactic acidosis and hypoglycemia can occur in various pediatric conditions. In young children with a history of fasting preceding these metabolic derangements, inborn errors of metabolism should be primarily considered. However, the Warburg effect, a rare metabolic complication, can also manifest in children with hematologic malignancies. Only a few reports of this condition in children have been published in the literature.
AIM
To identify the clinical course, treatment strategies, and outcomes of childhood hematologic malignancies with type B lactic acidosis.
METHODS
We performed a comprehensive search of the PubMed, Scopus, and Cochrane databases without any time restriction but limited to English language articles. The databases were last accessed on July 1st, 2023.
RESULTS
A total of 20 publications were included in the analysis, all of which were case reports or case series. No higher quality evidence was available. Among children with hematologic malignancies and Warburg effect, there were 14 cases of acute lymphoblastic leukemia and 6 cases of non-Hodgkin’s lymphoma including our illustrative case. Lactic acidosis occurred in 55% of newly diagnosed cases and 45% of relapsed cases. The mean age was 10.3 ± 4.5 years, and 80% of cases were male. The mean serum lactate was 16.9 ± 12.6 mmol/L, and 43.8% of the cases had concomitant hypoglycemia. Lactic acidosis initially subsided in 80% of patients receiving chemotherapy compared to 60% in the contrast group. The mortality rate of newly diagnosed cases was 45.5%, while the relapsed cases represented a 100% mortality rate. All 8 patients reported before 2001 died from disease-related complications. However, patients described in reports published between 2003 and 2023 had a 54.5% rate of complete remission.
CONCLUSION
This complication has historically led to fatal outcome; however, patients who received chemotherapy showed a more favorable response. Therefore, it is crucial to promptly initiate specific treatment in this context.
Light soaking effect on defect states distribution of Hydrogenated amorphous silicon investigated By means of constant photocurrent technique
Authors: Tibermacine Tawfik , Merazga Ammar 
Published: December 2023

In the present paper we have investigated, by using the constant photocurrent method in dc-mode (dc-CPM), the effect of the light soaking (LS) on the deep defect density (Nd) and the slope of the Urbach tail (E0) of a slightly phosphorus-doped hydrogenated amorphous silicon (a-Si:H) film prepared by Plasma-Enhanced Chemical Vapour Deposition (PECVD). By applying the derivative method, we have converted the measured data into a density of states (DOS) distribution in the lower part of the energy gap. The evolution of the sub-band-gap absorption coefficient and the CPMdetermined density of gap-states distribution within the gap versus the illumination time leads to: (i) an increase in the deep defect absorption without any significant changes in the Urbach tail (exponential part), (ii) a presence of more charged than neutral defects as predicted by the defect pool model, and (iii) a saturation point of the degradation of both optical absorption coefficient and density of deep states of slightly P-doped sample measured by dc-CPM. The constant photocurrent technique in dc-mode as a spectroscopy method for the defect distribution determination is, therefore, most reliable to study the light soaking effect on the stability of hydrogenated amorphous silicon layers used in solar cells manufacturing.
Le modèle non-linéaire K-E-fu et son application à l’étude De l’écoulement turbulent autour de profil aérodynamique
Authors: Ezzarfi Ahmed , Harbouch Bousselham 
Published: December 2023

Le but de ce travail est d’évaluer l’aptitude du modèle de turbulence nonlinéaire , mis au point par Park et al. (2003) [5], pour reproduire correctement l’anisotropie des contraintes normales du tenseur de Reynolds en proche – paroi. Les résultats obtenus sont comparés à ceux du modèle linéaire et du modèle standard . L’application concerne l’étude de l’écoulement turbulent bidimensionnel autour d’un profil aérodynamique NACA 0012, soumis à un angle d’incidence de et un nombre de Reynolds de 500.000. La méthode des volumes finis est utilisée pour résoudre les équations de conservation de la masse et de la quantité de mouvement. La prédiction de l’anisotropie est fortement liée aux corrections dans la région proche paroi. Le présent modèle est parfaitement réalisable et reproduit bien la relation non linéaire dans la région proche - paroi. A la lumière des résultats obtenus, on montre que le modèle linéaire et le modèle standard sont incapables à prédire correctement l’anisotropie des contraintes normales au voisinage de la paroi.
PROTEIN KINASES AS DRUG TARGET AGAINST TRYPANOSOMA BRUCEI
Authors: Verma Divya 
Published: December 2023

Protein kinases are the most studied proteins as drug targets against deadly disease ‘sleeping sickness. The crystal structures for the Trypanosoma brucei protein kinase A catalytic subunit isoform 1 (PKAC1) and cell division-related protein kinase 2 (CDK2) are still not known. Therefore, homology models were constructed for the two proteins, based on their known amino acid sequences. The catalytic sites of both the proteins were then compared with their respective human homologs. Except for some conformational differences, the active site of TbrPKAC1 was found to be quite similar to that of the human homolog. Therefore, TbrPKAC1 cannot be considered as a very good drug target. Whereas, in the case of TbrCDK2, along with huge conformational differences, some important differences in the structure and nature of the binding site were also noticed when compared to their human homolog. Virtual screening was performed for TbrCDK2 and selected hits were analysed for the ligand-protein interactions. This analysis showed many important variations in TbrCDK2 from human homolog, which can be further explored as potential drug target.