bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimalisasi Pemanfaataan Alat Peraga Lingkaran Pada Siswa SMP Widiatmika
Authors: Puspadewi Kadek Rahayu , Payadnya I Putu Ade Andre , Noviantari Putu Suarniti , Wibawa Kadek Adi , Atmaja Made Dharma 
Published: November 2023

The purpose of this community service is to provide a solution in the form of training and assistance to teachers and students in using the tool display. Widiatmika Middle School is a private school with its address on Jalan Raya Udayana Campus, Pondok Taman Nusantara No.01, Jimbaran. From the results of interviews with partners, it was found that the school was still limited in using visual aids, especially in learning mathematics. The use of this teaching aid in learning is very important in supporting learning process. Visual aids that are utilized optimally can provide better and systematic learning, directly or indirectly, and can provide convenience for the teaching and learning process in schools. Community service activities in the form of training on the use of circle props at Widiatmika Middle School have been running smoothly. This one-day activity has been carried out offline. The enthusiasm of the lecturers and students in providing assistance as well as the enthusiasm of the training teachers and students made this activity run smoothly Keywords: learning; teaching aids; mathematics Abstrak: Tujuan pengabdian masyarakat ini yaitu memberikan solusi berupa pelatihan serta pendampingan kepada guru dan siswa-siswi dalam menggunakan alat peraga. SMP Widiatmika merupakan sekolah swasta beralamat di Jalan Raya Kampus Udayana, Pondok Taman Nusantara No.01, Jimbaran. Dari hasil wawancara dengan mitra diperoleh permasalahan bahwa pihak sekolah masih terbatas dalam memanfaatkan alat peraga khususnya dalam pembelajaran matematika. Penggunaan alat peraga ini dalam pembelajaran sangat penting dalam menunjang proses pembelajaran. Alat peraga yang dimanfaatkan secara maksimal dapat memberikan pembelajaran yang lebih baik dan sistematis, secara langsung atau tidak langsung, serta dapat memberikan kemudahan bagi proses belajar mengajar di sekolah. Kegiatan pengabdian masyarakat berupa pelatihan pemanfaatan alat peraga lingkaran di SMP Widiatmika telah berjalan lancar. Kegiatan yang berlangsung selama satu hari ini telah dilaksanakan secara luring. Semangat para dosen dan mahasiswa dalam melakukan pendampingan begitu juga dengan antusias guru dan siswa pelatihan membuat kegiatan ini dapat berjalan dengan lancar.Kata kunci: alat peraga, pembelajaran; matematika
Pencegahan Stunting pada Anak Usia Dini Melalui Konsumsi Produk Ternak yang ASUH Di Desa Suka Damai Timur
Authors: Widya Rika , Setyaningrum Sri , Siregar Dini Julia Sari 
Published: November 2023

Stunting was a problem of chronic malnutrition for a long time and interferes with growth especially in early childhood. PKM activities conducted in PAUD and Kindergarten of Ihsanul Hasanah and Al-Hidayah East Sukadamai Village. The partner problems were the PAUD and Kindergarten in East Sukadamai Village never given education on the importance of consuming livestock products (eggs, meat and milk) and selecting that's products with the ASUH concept (Safe, Healthy, Whole, Halal) for stunting prevention in early childhood. The aim of PKM was to understanding teachers, parents and children about the importance of preventing stunting through the consumption of ASUH livestock products. The PKM method was lectures to parents and teachers. Telling story and socialization on eating livestock products to children. The PKM results show that increased understanding of parents and teachers of the importance of consuming livestock products and choosing ASUH livestock products to prevent stunting. PAUD and Kindergarten children enthusiastically listen to stories about stunting and begin to know that eggs, meat and milk were important for stunting prevention. Giving livestock products to children every two weeks. The conclusion of PKM was PKM activities increase the understanding of parents, teachers, and early childhood about stunting prevention with ASUH livestock products.Keywords: early childhood; livestock products; stunting Abstrak: Stunting merupakan masalah kurang gizi kronis yang terjadi dalam waktu cukup lama dan mengganggu pertumbuhan terutama anak usia dini. Kegiatan PKM dilakukan PAUD dan TK Ihsanul Hasanah dan TK Al-Hidayah Desa Sukadamai Timur. Permasalahan mitra yaitu PAUD dan TK di Desa Sukadamai Timur belum pernah diberikan edukasi pentingnya mengonsumsi produk ternak (telur, daging, dan susu) dan pemilihan produk hasil ternak dengan konsep ASUH (Aman, Sehat, Utuh, Halal) untuk pencegahan stunting pada anak usia dini. Tujuan PKM yaitu memberikan pemahaman kepada guru, orang tua, dan anak tentang pentingnya pencegahan stunting melalui konsumsi produk ternak yang ASUH. Metode PKM adalah ceramah terhadap orang tua dan guru. Dongeng pada anak-anak serta sosialisasi makan produk peternakan. Hasil PKM menunjukkan bahwa terjadi peningkatan pemahaman orang tua dan guru akan pentingnya mengonsumsi produk ternak dan pemilihan produk ternak yang ASUH untuk mencegah stunting. Anak-anak PAUD dan TK antusias mendengarkan dongeng tentang stunting sehingga mulai mengetahui bahwa telur, daging, dan susu sangat penting untuk pencegahan stunting. Pemberian produk ternak pada anak-anak setiap dua minggu. Kesimpulan PKM adalah kegiatan PKM meningkatkan pemahaman orang tua, guru, serta anak usia dini tentang pencegahan stunting dengan produk ternak yang ASUH.Kata Kunci: anak usia dini; produk ternak asuh; stunting
Penyuluhan Dan Pelatihan Pengolahan Makanan Sehat Berbasis Kelor Dalam Rangka Penanganan Stunting Desa Maskuning
Authors: Ningsih Indah Yulia , Suryaningsih Ika Barokah , Hidayat Mochammad Amrun 
Published: November 2023

Stunting is a health problem currently the government's primary concern because it affects the quality of human resources. One of the areas that is still being targeted for handling stunting is Maskuning Wetan Village, Pujer District, Bondowoso Regency, East Java, with 14.36% of stunting cases. Diet, including the food type, is important in managing stunting. Most mothers in this area have lack knowledge in healthy food processing. Therefore, in this service program, several steps to handle stunting related to healthy food processing were carried out through counselling and training activities. The main ingredient used is the Moringa plant, which is known in many countries to overcome malnutrition because it is rich in nutrients, obtained easily, and affordable. The activity program is hoped to support the government's efforts in reducing the prevalence of stunting in Maskuning Wetan Village. Keywords: healthy food; moringa; stunting Abstrak: Stunting merupakan masalah kesehatan yang menjadi perhatian utama pemerintah hingga saat ini karena berpengaruh pada kualitas sumber daya manusia. Salah satu daerah yang masih menjadi sasaran penanganan stunting adalah Desa Maskuning Wetan, Kecamatan Pujer, Kabupaten Bondowoso, Jawa Timur dengan kasus stunting sebanyak 14,36%. Pola makan termasuk jenis makanan berperan penting dalam penanganan stunting. Sebagian besar ibu di daerah tersebut masih banyak yang belum mengetahui cara pengolahan makanan sehat. Oleh karena itu, pada program pengabdian ini dilakukan beberapa langkah penanganan stunting terkait pengolahan makanan sehat berupa kegiatan penyuluhan dan pelatihan. Bahan utama yang digunakan adalah tanaman kelor yang telah dikenal di berbagai negara untuk mengatasi malnutrisi karena kaya akan kandungan nutrisi, mudah diperoleh, dan terjangkau. Dengan adanya program kegiatan ini diharapkan dapat mendukung upaya pemerintah dalam menurunkan prevalensi stunting di Desa Maskuning Wetan.Kata kunci: kelor; makanan sehat; stunting
MAKSIMALISASI PENINGKATAN KEPUASAN PELANGGAN PADA PT. LAUTAN ABADI PRATAMA MELALUI PROMOSI DAN KUALITAS PELAYANAN PADA PT. LAUTAN ABADI PRATAMA
Authors: Syaifullah Syaifullah , Nasib Nasib 
Published: November 2023

Penelitian ini bertujuan untuk mengetahui pengaruh promosi dan kualitas pelayanan terhadap kepuasan pelanggan. Jenis penelitian ini yaitu kuantitatif. Data penelitian diperoleh melalui penyebaran kuesioner dan dianalisis dengan analisis regresi linier berganda. Hasil penelitian menyatakan bahwa secara parsial promosi berpengaruh positif dan signifikan terhadap kepuasan pelanggan, kualitas pelayanan berpengaruh positif dan signifikan terhadap kepuasan pelanggan, dan secara simultan promosi dan kualitas pelayanan bersama-sama berpengaruh positif dan signifikan terhadap kepuasan pelanggan PT. Lautan Abadi Pratama. Implikasi temuan dalam penelitian ini bahwa bagi konsumen baru pemanfaat media sosial beruapa facebook dan instagram harus disediakan dan diawasi oleh departemen tertentu guna memberikan sumber informasi mengenai keunggulan dan biaya yang harus dikorbankan oleh setiap konsumen. Selanjutnya manajemen memberikan garansi penuh atas waktu pengiriman dan keamanan dari barang pelanggan yang dikirim dari Batam-Jakarta atau Jakarta-Batam. Hal ini merupakan upaya manajemen dalam menjaga pelanggannya serta sebagai langkah dalam menarik pelanggan baru dalam pemanfaatan jasa pengakutan barang.
IMPACT OF PRICE PROMOTION AND WORD OF MOUTH ON PURCHASE INTENTION ON LAZADA (CASE STUDY BANDUNG'S CONSUMERS IN 2020)
Authors: Sakina Ihda Salma 
Published: November 2023

The more technological advances are developed, the more technological innovations there are. One of the new technology is online shopping. People new behaviour is online shopping because they can easily buy goods without going out. The increasing public interest in online shopping has led to e-commerce brands in Indonesia. Lazada, as one of the e-commerce in Indonesia, needs to strengthen its marketing strategy, so people can be interested in making payments on the Lazada platform.
This study aims to analyze whether price promotion and word of mouth can affect the purchase intention of Indonesian people, especially the city of Bandung. The population in this study were the people of Bandung who had shopped or knew about Lazada. Data collection technique with a questionnaire, while the data analysis technique used multiple linear regression analysis, classical assumptions (normality test, multicollinearity test, heteroscedasticity), statistical tests (t-test, f test and coefficient of determination).
From the classical assumption analysis results, the normality test with Kolmogorov Smirnov was obtained significantly more than 0.05, which means that the data distribution is normal. The multicollinearity test received close VIF and Tolerance values one, so it can be concluded that the regression model does not have a problem with multicollinearity. In contrast, the heteroscedasticity test was carried out by the Glejser method declared no trouble found.
Based on the results of multiple linear regression analysis from the t-test, the finding is that, partially, purchase intention significantly affects price promotion and word of mouth. The results of the F-test show that simultaneous price promotion and word of mouth are significant towards purchase intention where f count > f table.
PENGARUH STRESS KERJA, KONFLIK PERAN, KEPUASAN KERJA DAN BUDAYA ORGANISASI TERHADAP KINERJA PEGAWAI DINAS KOPERINDAG KOTA SAWAHLUNTO
Authors: Nilawati Nilawati , Heliyani Heliyani 
Published: November 2023

Penelitian ini bertujuan untuk melihat pengaruh (1) Stres kerja, Konflik peran, Kepuasan kerja, Budaya organisasi terhadap kinerja pegawai Dinas Koperindag Kota Sawahlunto. Populasi Sampel yang digunakan sebanyak 33 orang dengan menggunakan teknik sampling jenuh (sensus). Teknik analisis data adalah regresi linear berganda dengan memenuhi persyaratan uji asumsi klasik yakninya uji normalitas, multikolinearitas dan heteroskedastisitas. Hasil penelitian ini menunjukan bahwa (1) Stres kerja memberikan pengaruh signifikan negatif terhadap kinerja pegawai Dinas Koperindag Kota Sawahlunto (2) Konflik peran berpengaruh signifikan negatif terhadap kinerja pegawai Dinas Koperindag Kota Sawahlunto (3) Kepuasan Kerja berpengaruh signifikan positif terhadap kinerja pegawai Dinas Koperindag Kota Sawahlunto, (4) Kepuasan Kerja berpengaruh signifikan positif terhadap kinerja pegawai Dinas Koperindag Kota Sawahlunto (5) Stres kerja, konflik peran, kepuasan kerja dan budaya organisasi secara bersama-sama berpengaruh signifikan terhadap kinerja pegawai Dinas Koperindag Kota Sawahlunto.
Effects of dietary mycotoxins and mycotoxin adsorbent additives on production performance, hematological parameters, and liver histology in juvenile Nile tilapia (Oreochromis niloticus)
Authors: Fornari Darci Carlos , Peixoto Silvio , Ksepka Steven P. , Bullard Stephen A. , Rossi Waldemar , Nuzback Dennis E. , Davis D. Allen 
Published: November 2023

Mycotoxins are fungal secondary metabolites that can adversely affect animals consuming contaminated feeds. This 71-day feeding trial was conducted to assess the effects of dietary deoxynivalenol plus zearalenone (DON+ZEN = 1.6 + 0.3 ppm), and fumonisins (FUM = 15 ppm), and three adsorbent additives on the production performance, hematological parameters, and liver histology of juvenile Nile tilapia. A mycotoxin-free diet (Control) formulated to contain 35% protein and 8% lipid was spiked with either DON+ZEN or FUM using contaminated corn meals replacing portions of non-spiked corn. Subsequently, three out of four DON+ZEN- and FUM-spiked diets were supplemented (0.5%) with an adsorbent. The research was carried out in a recirculating water system (2,500 L) with a controlled temperature of (25.9 ± 1.1°C), feeding was carried out twice a day at rates ranging from 5 to 8%. The experiment included nine treatments with five replications, each experimental unit consisting of an aquarium with a useful volume of 75-L and fifteen juvenile Nile tilapia (average initial weight of 4.0 ± 0.1 g). Mycotoxin-spiked diets without added adsorbent supported lower final biomass and survival of Nile tilapia relative to control and adsorbent containing diets (P ≤ 0.05). Histological examinations revealed liver inflammation evidenced by lymphocytic infiltration adjacent to pancreatic tissue in fish fed mycotoxin-spiked diets without added adsorbent. Mycotoxin contamination significantly increased HSI (hepato somatic index), which was reverted to the Control value or reduced further by adsorbent addition. Lowest and intermediate hematocrit values were observed in groups fed mycotoxin-spiked diets without and with added adsorbents, respectively. Our results reinforce the importance of using adsorbents and the need to investigate the effect of sub-lethal concentrations of mycotoxins in aquaculture feeds.
3D bioprinting of dECM-incorporated hepatocyte spheroid for simultaneous promotion of cell-cell and -ECM interactions
Authors: Kim Min Kyeong , Jeong Wonwoo , Jeon Seunggyu , Kang Hyun-Wook 
Published: November 2023

The cell spheroid technology, which greatly enhances cell-cell interactions, has gained significant attention in the development of in vitro liver models. However, existing cell spheroid technologies still have limitations in improving hepatocyte-extracellular matrix (ECM) interaction, which have a significant impact on hepatic function. In this study, we have developed a novel bioprinting technology for decellularized ECM (dECM)-incorporated hepatocyte spheroids that could enhance both cell-cell and -ECM interactions simultaneously. To provide a biomimetic environment, a porcine liver dECM-based cell bio-ink was developed, and a spheroid printing process using this bio-ink was established. As a result, we precisely printed the dECM-incorporated hepatocyte spheroids with a diameter of approximately 160–220 μm using primary mouse hepatocyte (PMHs). The dECM materials were uniformly distributed within the bio-printed spheroids, and even after more than 2 weeks of culture, the spheroids maintained their spherical shape and high viability. The incorporation of dECM also significantly improved the hepatic function of hepatocyte spheroids. Compared to hepatocyte-only spheroids, dECM-incorporated hepatocyte spheroids showed approximately 4.3- and 2.5-fold increased levels of albumin and urea secretion, respectively, and a 2.0-fold increase in CYP enzyme activity. These characteristics were also reflected in the hepatic gene expression levels of ALB, HNF4A, CPS1, and others. Furthermore, the dECM-incorporated hepatocyte spheroids exhibited up to a 1.8-fold enhanced drug responsiveness to representative hepatotoxic drugs such as acetaminophen, celecoxib, and amiodarone. Based on these results, it can be concluded that the dECM-incorporated spheroid printing technology has great potential for the development of highly functional in vitro liver tissue models for drug toxicity assessment.
Assessing the impact of ventilation systems on indoor air quality: a mock-up experiment in Dubai
Authors: Jung Chuloh , El Samanoudy Gamal , Alqassimi Nahla , Sherzad Mohammed 
Published: November 2023

Indoor Air Quality (IAQ) has become an important concern in Dubai, driven by public health awareness, environmental regulations, and government initiatives. The Dubai Municipality has introduced guidelines and standards for IAQ in residential and non-residential buildings, emphasizing ventilation, material selection, and testing protocols. IAQ monitoring and testing are encouraged, and public awareness campaigns educate individuals about IAQ and its impact on health. Green building regulations in Dubai also address IAQ considerations. The Dubai Municipality has comprehensively assessed IAQ in public buildings, leading to stringent regulations. However, research on IAQ improvement and challenges associated with apartment ventilation systems is limited. This study aims to evaluate the IAQ improvement and potential issues of a ventilation system in an apartment through a mock-up experiment. Factors such as air volume, ventilation system type, and supply/exhaust duct configuration are analyzed. The results show that installing a ventilation device with a ventilation rate of 0.3–0.8 times/h reduces Formaldehyde (HCHO) and Volatile Organic Compounds (VOCs) concentrations by 30%–50%. The IAQ improvement is not significantly influenced by air volume. Each room supply/exhaust method shows a 10% higher reduction in VOC concentrations than the supply/kitchen exhaust unit method. Preventing backflow and addressing cold drafts are recommended during ventilation system installation. Noise measurements comply with standards in most cases. These findings contribute to developing guidelines for ventilation system design and installation in apartments, promoting healthier indoor environments. Further research with a broader range of ventilation devices and real-world conditions is recommended to validate these findings.
Novel circular RNA circ-0002727 regulates miR-144-3p/KIF14 pathway to promote lung adenocarcinoma progression
Authors: Li Yang , Hong Xiu , Zhai Jingfang , Liu Ying , Li Rui , Wang Xiuli , Zhang Youwei , Lv Qian 
Published: November 2023

Objective: Circular RNAs (circRNAs) have been shown to participate in various cancers via sponging miRNAs (microRNAs). However, their role in lung adenocarcinoma (LUAD) remains elusive.Methods: The transcriptome data and corresponding clinical information of lung adenocarcinoma samples were extracted from The Cancer Genome Atlas (TCGA) and Gene Expression Omnibus (GEO) database. Differentially expressed circRNAs (DEcircRNAs), differentially expressed miRNAs (DEmiRNAs), and differentially expressed genes (DEgenes) were identified and further used to constructed a circRNA-associated competing endogenous RNA (ceRNA) network. Real-Time qPCR analysis was conducted to examine gene expression at transcriptional level. The regulatory mechanisms of circRNA-miRNA-gene were validated by dual-luciferase reporter array and RNA pull-down assay. Cell growth, migration and invasion were evaluated by CCK-8 assay, colony formation assay and transwell assay, respectively.Results: Based on public microarray data, we systematically constructed a circRNA-associated ceRNA network including 11 DEcircRNAs, 8 DEmiRNAs and 49 DEgenes. Among the ceRNA network, we found that circ-0002727 was a key regulatory and was further confirmed to be upregulated in LUAD cancer cells. Subsequently, we found that silencing of circ-0002727 significantly suppressed the LUAD cell proliferation, migration and invasion in vitro. Mechanistically, we showed that circ-0002727 could competitively bind miR-144-3p to enhance the KIF14 expression in LUAD cells. Rescue assays indicated that circ-0002727 could regulate LUAD cell proliferation through modulating miR-144-3p/KIF14 pathway. Besides, KIF14 expression level was positively correlated with TNM stage and metastasis, and patients with high KIF14 expression suffered poor prognosis.Conclusion: Taken together, our study revealed that circ-0002727 could act as a ceRNA to regulate LUAD progression via modulating miR-144-3p/KIF14 pathway, providing a potential therapeutic target for LUAD.
Ethnomedicinal values of Boerhaavia diffusa L. as a panacea against multiple human ailments: a state of art review
Authors: Das Sarita , Singh Puneet K. , Ameeruddin Shaikh , Kumar Bindhani Birendra , Obaidullah Wajdi J. , Obaidullah Ahmad J. , Mishra Snehasish , Mohapatra Ranjan K. 
Published: November 2023

Ethnopharmacological relevance: Therapeutic botanicals (plants and derivatives) are in use since antiquity for various health ailments. The ethnic community is the repository of the information, the multifactorial therapeutic applications of which may often need scientific validation. The spreading hogweed or Boerhaavia diffusa L., also known as Punarnava, is a reassuring medicinal herb with diverse pharmacological benefits. It is used in Ayurveda in Asia and Africa as a rejuvenator or “Rasayan” for its excellent antiaging and antioxidant properties.Aim: The study aimed at compiling the state-of-art knowledge of the medicinal benefits of Boerhaavia diffusa L. and unraveling the unexplored commercially useful bioactive constituents by establishing their possible pharmacological benefits.Methods: The data from published literature, confined to pharmacological manifestations of various phytocomponents of Boerhaavia diffusa L. or its parts like root, leaf and stem were extracted from scientific databases, Google, Science Direct, PubMed, etc. using its antifungal, antibacterial, anticancer, anti-inflammatory, antidiabetic, hepatoprotective, cardioprotective, renoprotective, antifertility benefits and molecular docking study as search strings and keywords. Further, the reported in silico studies for bioactivity and bioavailability are detailed.Results: The botanicals possess numerous bioactive compounds, the most widely reported ones being phenolic (punarnavoside, trans-caftaric acid, boerhavic acid), rotenoid (boeravinones A-J), flavonoid (borhaavone, quercetin, kaempferol), isoflavonoid (2′-O-methyl abronisoflavone), alkaloid (punarnavine), steroid (boerhavisterol, β-Ecdysone), anthracenes and lignans (liriodendrin, syringaresinol mono-β-D-glucoside). Some of the reported reassuring benefits of their purified forms or even the crude extracts are antidiabetic, antimicrobial, anticancer, antioxidant, anti-inflammatory, hepatoprotective, renoprotective, cardioprotective, antifertility, etc.Conclusion: The article provides an extensive study on such pharmacological utility to support the ethnomedicinal use of Boerhaavia diffusa L. and propose possible mechanism of the various bioactive compounds in optimising metabolic dysfunctions, healing and protecting vital body organs, often related to the magnificent antioxidant property of this ayurvedic panacea. Further, establishing specific roles of its yet-to-explore bioactive constituents for diverse pharmacological applications is suggested.