bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review on the Recent Progress of Layered Double Hydroxides
(LDHs)-based Catalysts for Heterocyclic Synthesis
Authors: Farouki Khadija El , Kacem Marieme , Dib Mustapha , Ouchetto Hajiba , Hafid Abderrafia , Khouili Mostafa 
Published: October 2023

Abstract:
Over the past decade, heterocyclic compounds and their derivatives have emerged as
promising substances with potential pharmacological applications due to their interesting biological
properties. The significance of heterocyclic compounds in drug discovery and development is evident from the fact that a majority of drugs in the pharmaceutical market incorporate heterocyclic
compounds as active substances or ingredients. Various synthetic methods and advancements have
been devised to prepare these heterocyclic compounds using diverse catalysts under mild conditions. Layered double hydroxides (LDHs)-based materials have gained considerable attention
across different fields, and their usability can be significantly enhanced via the selection of metal
cations, their molar ratios, surface complexation, and intercalation modifications. The synthesis and
application of LDH-based materials as catalysts have garnered increasing interest due to their exceptional properties. Moreover, LDH-based materials have found extensive use as heterogeneous
catalysts in the synthesis of numerous heterocyclic compounds. This review presents the latest developments in the catalytic application of LDH-based materials as solid heterogeneous catalysts in
the synthesis of heterocyclic compounds, covering literature published from 2018 to 2023.
Effects of Probiotics and Magnesium Co-supplementation on Stress Levels and Quality of Life in Obese Patients with Depressed Mood: A Randomized, Double-blinded Placebo-controlled Clinical Trial
Authors: Ghasvarian Marzieh , Mahboobi Sepideh , Sadeghi Reza , Ghaem Haleh , Hedayati Arvin , Alipour Shohre , Valisoltani Neda , Harsini Asma Rajabi , Eftekhari Mohammad Hassan 
Published: October 2023

Background and Objectives:
Obesity is strongly associated with mood disorders. There is evidence that obesity and mood disorders may be related pathologically. Depression and manic episodes are more common among overweight or obese individuals. Human subjects have reported the restorative effects of probiotic supplementation on neuroendocrine functions. Gut microbiota, neuroendocrine status, and obesity are related. Magnesium enriches the gut microbiota. Based on the association between gut microbiota, magnesium levels, obesity, and neuropsychiatric disorders, we examined the possibility of co-supplementation of probiotics and magnesium in humans.

Methods:
For 74 individuals, demographic data, quality of life scores (SF -12), depression, anxiety, and stress scores (DASS-21) were collected, along with body mass index (BMI), waist circumfer-ence, and serum cortisol levels. An SPSS analysis was performed.

Results:
Both the intervention and control groups experienced significant reductions in depression, anxiety, and stress. A significant improvement in mental health, role-emotional function, and vital-ity was observed in the probiotic and magnesium supplement group.

Conclusion:
Magnesium supplements and probiotics increased vitality (VT) and mental health (MH) and reduced functional impairment from emotional stress (RE). They experienced fewer functional limitations because of physical conditions.
The Protective Effect of Ramelteon and in combination with Dexamethasone on the Lipopolysaccharide-induced Cytokine Storm in mice
Authors: A. Al-dabbagh Marwa , B. Sahib Hayder 
Published: October 2023

Cytokine Storm Syndrome (CSs) is a potentially life threatening condition, characterized by robust elevated; of circulating pro- inflammatory cytokines; occurring after a hyperactive immune system. Is a well-known as a worldwide health problem, leading to multi-organ failure and death. Objectives: This study was carried out to investigate the protective role and probability of additive or synergistic anti-inflammatory activity; of ramelteon and in combination with dexamethasone on the lipopolysaccharide (LPS) induced “Cytokine Storm” on mice model and its potential regulatory mechanism(s). Methods: Sixty Swiss albino male mice of ;( 25 ± 5 grams; 8-12 weeks) had free access to food and water. After 2weeks of adaptation, mice; randomly separated in five groups (n =12): Group I, mice received (0.9% N\S i.p.); Group II, mice received (5mg\kg i.p.) LPS only .Group III, mice received (2.5mg/kg, i.p.) dexamethasone, Group IV, mice received (100mg/kg i.p.) ramelteon, Group V, mice received half dose of dexamethasone+ ramelteon combination (1.25 mg\kg i.p +50mg\kg i.p). For systematic inflammatory stimulation mimicking “cytokine storm” LPS; E. coli O55:B5 (5mg\kg i.p.) was induced within one hr. After 48h the effects of interventional agents and vehicle or LPS challenge; on lung, heart, liver, kidney histopathological changes, and levels of inflammatory cytokines :( IL-6, IL8 IL-1β, and TNF-α) in the serum were detected. Results: IL-1β, IL-6, IL8 and TNF-α elevated serum levels significantly reduced (p<0.001) in all treatment group. Additionally, they ameliorated the histopathological changes induced by (LPS) and improving macroscopic scores (p<0.001). Conclusion: In conclusion, ramelteon treatment had a diverse protective effects against “Cytokine Storm” with a mechanism based on attenuation serum levels of inflammatory cytokines (IL-1β, IL-6, IL-8 and TNF-α)and through reduction of histopathological damage during endotoxemia induced via LPS challenge on male mice model. RAM/DEX combination had superior advantage than an agent use alone probably via synergistic anti-inflammatory activity.
In silico study of new carbonic anhydrase inhibitor derivatives bearing 1, 3, 4-Oxadiazole moiety with promising anti-cancer activity.
Authors: Saad Aljubouri Riyam , H. Naser Noor 
Published: October 2023

Objectives: Molecular docking simulations were performed to assess the theoretical binding affinities of six (6) compounds created where they are derivatives having 1,3,4, oxadiazole moiety, and their target was cancer and Human carbonic anhydrase IX (PDB code: 6U4T). Using ChemDraw Ultra 12.0, the molecular structure was meticulously sketched. Molecular Operating environment software was used to verify the developed compounds by looking at their S. score and Rmsd values. Promising activity was seen with these proteins from the theoretically generated compounds, which exhibited strong binding contacts with the receptor active pocket.

Methods: Chemically by joining together several oxadiazole derivatives, sulfanilamide analogues (IVa-IVd) may be created in the lab. Molecular docking and ligand/receptor priming by MOE software.
Results: Acetazolamide was selected because it had the same pharmacophore as the sulfanilamide group, and cisplatin was used in clinical trials for cancer therapy. IVc and IVa yielded max score and irrevocable relationship compared with acetazolamide and cisplatin.
Conclusion: The MOE docking results validated the potent anticancer activity, the identified compounds showing good binding affinity with target proteins relative to the reference drugs (Acetazolamide and cisplatin). The most effective anticancer compounds were IVc and IVa, which yielded a maximum score with a Rmsd of less than 2, the MOE docking results were able prove this.
Compounds IVc and IVa exhibited the greatest cytotoxic impact of the synthetic compounds against MCF7, and all four synthesized compounds showed a superior safety profile than the standards in MCF10a.
The Auditor’s Responsibility for Noncompliance with Laws and Regulations: A Case of Unauthorized Account Activity at Wells Fargo
Authors: Keyser John D. , Smith Jason L. 
Published: October 2023

ABSTRACT
In September 2016, the Consumer Financial Protection Bureau (CFPB) announced an enforcement action against Wells Fargo related to improper sales practices. Following investigations revealing widespread abuse by thousands of employees (e.g., opening deposit and credit accounts without customer consent), Wells Fargo paid civil monetary penalties of $185 million and other substantial punitive fees and fines. This case study uses this real-world example to explore the influence of materiality on the scope of an audit, the auditor’s responsibility for detection and communication of noncompliance with laws and regulations (NOCLAR), and the auditor’s consideration of the control environment in the evaluation of internal controls over financial reporting (ICFR). After completing the case, learners are able to discuss relevant professional standards and recognize the impact of materiality considerations on decisions about financial statement misstatements, NOCLAR, and internal control deficiencies.
JEL Classifications: M41; M42.
Mengelola Emosi Saat Mendampingi Anak Pembelajaran Jarak Jauh
Authors: Lisnawati Ruhaena  , Permata Ashfi  , Qatrunnada Rizqi Zulfa , Nabilah Dita Silviana  , Aprilia Firdaus  , Farah Aulia Rahmawati  , Ummu Kaltsum  
Published: October 2023

Perubahan sistem pendidikan yang awalnya dilakukan secara tatap muka, saat ini harus dilakukan pembelajaran jarak jauh akibat pandemi Covid-19. Pembelajaran jarak jauh mengharuskan orang tua turut serta mengawasi anak selama pembelajaran berlangsung. Pengawasan tersebut kemudian menimbulkan stres dan ketidakmampuan mengelola emosi pada orang tua. Hasil pre-test dan post-test menunjukkan bahwa ... Program pengabdian masyarakat berupa webinar ini dilaksanakan untuk membantu orang tua dan tenaga pendidik mengelola emosi selama pembelajaran jarak jauh. Webinar berisi materi tentang emosi serta bagaimana mengelola emosi tersebut menggunakan berbagai teknik. Webinar berlangsung dengan lancar dan mampu memberikan insight kepada peserta.
The Popular Culture of Upin & Ipin and Adit & Sopo Jarwo Animated Series
Authors: Adjikusuma Evelyna Nissi , Dukut Ekawati Marhaenny 
Published: October 2023

Popular culture refers to a culture enjoyed by the mass because it is closely related to people’s lives. One such pop culture product is film. In this paper, the the main data for discussion is a Malaysian animated series, Upin Ipin and the Indonesian animated series, Adit Sopo Jarwo The first episode of Upin Ipin and the two episodes of Adit Sopo Jarwo are used to see how the series used popular culture strategies to maintain their popularity, and how through analyzing the plot, similar moral values are found. The method used to analyze is s Roland Barthes’ semiotics. The result of the research showed that both animated series were the products of pop culture because the series fulfilled the characteristics of satisfying viewers, easy to obtain, showed an eagerness to please viewers, and reflected the culture of the Malaysian and Indonesian society. Two similar moral values which were obedience and gratefulness were found in those animated series. The obedience was shown through young characters who were not scared to confront older people, but also show how to respect elders . Gratefulness in the series in the animated series were found through seeing the characters see the positive sides of life
Consumption behavior towards the circular economy
Authors: Kulli Altin , Grzywińska-Rąpca Małgorzata , Duarte Nelson , Goci Enkelejda , Pereira Carla 
Published: October 2023

Abstract
The article focuses on the consumption of goods used by consumers of different generations from 3 different countries: Albania, Polish and Portugal. The aim of the analysis was to identify respondents‘ indications concerning: (1) knowledge of the definition of the circular economy, (2) declared by respondents places of purchase of used products and (3) type of purchased products used by respondents. The analysis was conducted among 495 respondents from Albania, Polish and Portugal representing three generations (X, Y, Z). Correspondence analysis was used for statistical data analysis. Statistically significant differences in knowledge of the definition of the circular economy were shown between respondents from Albania, Polish and Portugal. It was also found that respondents‘ preferences regarding the place of purchase of second-hand goods are differentiated (at a statistically significant level) by nationality and year of birth (generation). The obtained results open the possibility of further research aimed at identifying different behaviors among these groups of consumers. The presented work, both in the cognitive and application part, can be a source of knowledge and popularization of research, as well as a source of inspiration for in-depth reflection and scientific discussion. The analyses presented in the publication may complement the existing research in the field of circular economy. Extending the survey to other EU countries can help define a strategy for policymakers, manufacturers and retailers to make greater use of circular economy solutions, while maintaining the viability of their operations.
Gender determination from periocular images using deep learning based EfficientNet architecture
Authors: Nambiar Viji B , Ramamurthy Bojan , Veeresha Pundikala 
Published: October 2023

Abstract
In this study, we obtain a sex prediction algorithm based on CNN in two ways - building a red Convolutional Neural Network (CNN) model from scratch and via transfer learning. We built a model from scratch and compared it with fine-tuned EfficientNetB1. We use these models for gender determination using periocular images and compare the two models depending on the accuracy of the models. The CNN model proposed from scratch yields an accuracy of 94.46% while the fine-tuned EfficientNetB1 yields an accuracy of 97.94%. This paper is one of the first works in determining gender from periocular images in the visible spectrum using a CNN model built from the outset.
On the complex properties of the first equation of the Kadomtsev-Petviashvili hierarchy
Authors: Sivasundaram Seenith , Kumar Ajay , Singh Ratnesh Kumar 
Published: October 2023

Abstract
This work studies the first equation of the Kadomtsev-Petviashvili (KP) hierarchy. The sine-Gordon expansion method (SGEM) and the rational SGEM (RSGEM) are applied to the governing model. RSGEM is the developed version of SGEM. New complex travelling wave solutions, logarithmic and complex function properties are obtained. Several simulations such as 2D, 3D and contour surfaces of the obtained results are plotted. Physical meanings of these solutions are also reported. Strain conditions are also extracted.
A second order numerical method for singularly perturbed Volterra integro-differential equations with delay
Authors: Erdoğan Fevzi 
Published: October 2023

Abstract
This study deals with singularly perturbed Volterra integro-differential equations with delay. Based on the properties of the exact solution, a hybrid difference scheme with appropriate quadrature rules on a Shishkin-type mesh is constructed. By using the truncation error estimate techniques and a discrete analogue of Grönwall’s inequality it is proved that the hybrid finite difference scheme is almost second order accurate in the discrete maximum norm. Numerical experiments support these theoretical results and indicate that the estimates are sharp.
State of the Art Emission Inventory and Their Application: Literature review
Authors: Lavrič Petra Dolšak , Kukec Andreja , Žabkar Rahela 
Published: October 2023

Abstract
Currently, the complex bottom-up emissions inventories are in rise. Itsdevelopment is essential for both understanding the sources of air pollutionand designing effective air pollution control measures. Anyway, the mainchallenge to get the most reliable emissions evidence is the variety ofcontributing sources, the complexity of the technology mix and the lack ofreliable emission factors. The input data bases are improving constantly, bymore reliable statistics and survey-based data. Our study reveals thestrengths and deficiency of currently published scientific papers on the topicof emission inventory. With that purpose, 40 crucial scientific papers wereselected. We first highlight the period and geographic region, when and wherethe inventories were made for. We then summarize the sector-basedestimates of emissions of different species contained by SNAP sectors inselected inventories. Additionally, the resolution of inventories is analysed.Finally, the last section summarizing common ways of assessing andvalidating inventories and their main purpose. This review shows that there isstill a lot of chance to improve emissions inventories in a way to develop inputdata and emission factors for different technologies and activities or todevelop inventories on fine grids. Those efforts will give us wider knowledgeabout pollution sources and will lead to accepted better air quality policy.
Macrophages Trajectories Smoothing by Evolving Curves
Authors: Lupi Giulia , Mikula Karol , Park Seol Ah 
Published: October 2023

Abstract
When analyzing cell trajectories, we often have to deal with noisy data due to the random motion of the cells and possible imperfections in cell center detection. To smooth these trajectories, we present a mathematical model and numerical method based on evolving open-plane curve approach in the Lagrangian formulation. The model contains two terms: the first is the smoothing term given by the influence of local curvature, while the other attracts the curve to the original trajectory. We use the flowing finite volume method to discretize the advection-diffusion partial differential equation. The PDE includes the asymptotically uniform tangential redistribution of curve grid points. We present results for macrophage trajectory smoothing and define a method to compute the cell velocity for the discrete points on the smoothed curve.
Élaboration et appréciation d’un cours sur les perspectives autochtones destiné à la formation à l’enseignement : le cas d’une université québécoise
Authors: Lavoie Constance , Blanchet Patricia-Anne , O'Bomsawin Suzie , Moisan Sabrina , Bernard David , Joncas Jo Anni 
Published: October 2023

Le 62e appel à l’action de la Commission de vérité et réconciliation (CVR) du Canada incite les gouvernements à « prévoir les fonds nécessaires pour permettre aux établissements d’enseignement postsecondaire de former les enseignants sur la façon d’intégrer les méthodes d’enseignement et les connaissances autochtones dans les salles de classe » (2015, p. 256). Plusieurs universités canadiennes ont déjà entamé l’autochtonisation de leurs programmes de formation à l’enseignement, alors que les universités québécoises francophones commencent à peine ce processus. Cet article relate le parcours d’inclusion d’un cours sur les perspectives autochtones à la Faculté d’éducation de l’Université de Sherbrooke, au Québec. L’argumentaire et les résultats s’articulent autour de ces deux questions : Comment développer un cours sur les perspectives autochtones pour les programmes de formation initiale à l’enseignement? Quelle appréciation en retirent les personnes étudiantes en enseignement ayant suivi ce cours? Méthodologiquement, cette étude suit un processus de recherche-action collaborative. Onze personnes ont participé à l’élaboration du cours et vingt-cinq personnes étudiantes en enseignement ont commenté le cours proposé. Les résultats préliminaires révèlent l’importance de la coconstruction et de la coréalisation d’un tel cours par et avec les personnes autochtones et les organisations scolaires autochtones. Il s’en dégage que les personnes étudiantes en enseignement, qu’elles soient Allochtones ou Autochtone, ressortent de ce cours satisfaites et s’engagent à inclure les perspectives autochtones dans leurs classes.
Peningkatan Pengetahuan Tata Laksana Trauma Gigi Sulung pada Anggota Komunitas BCApril21
Authors: Hayuningtyas Ria Aryani , Laksmiastuti Sri Ratna , Lestari Sri , Louisa Marie , Livia Kurniawan Florencia 
Published: October 2023

INTISARI
Sebuah penelitian mengemukakan prevalensi global sebesar 22,7% dari trauma merupakan trauma yang melibatkan gigi sulung. Sejumlah 18% dari cedera fisik merupakan cedera oral yang dialami oleh anak usia 0-6 tahun. Trauma dental pada anak akan mempengaruhi kesehatan gigi mulut mereka. Penanganan trauma dental pada anak dapat menjadi tantangan yang sulit bagi orang tua dan pasien tersebut. Penyuluhan dan pelatihan diadakan untuk meningkatkan pengetahuan para ibu dalam tata laksana trauma gigi sulung dan pemeliharaan Kesehatan gigi mulut anak. Kegiatan ini dilaksanakan oleh dosen dari Fakultas Kedokteran Gigi Universitas Trisakti pada bulan Mei 2023. Kegiatan ini diberikan kepada anggota komunitas Birth Club April 2021. Setelah kegiatan, peserta menunjukan adanya peningkatan pengetahuan yang dapat dilihat dari jumlah jawaban benar pada post-test. Persentase kenaikan jumlah jawaban benar post-test adalah 8,82% lebih tinggi dari pre-test. Dukungan dan partisipasi dari komunitas sangat membantu keberhasilan acara ini. Diharapkan dengan adanya kenaikan pengetahuan orang tua, masalah kesehatan mulut pada anak dapat dicegah dengan anak dapat tumbuh dengan sehat dan gigi yang kuat.

Keywords: trauma dental, gigi sulung, kesehatan gigi dan mulut
Automatic Analysis of Lexical Complexity: Evaluating The Linguistic Performance of The National and International Publication
Authors: Martin Laily , Suraiya Lucy , Chan Almaghvirah 
Published: October 2023

<p>This research is a kind of a comparison study that deals with lexical complexity in the Indonesian scholars’ journal articles. The analysis covers 98 journal articles from the national and international publication using 25 lexical complexity indices. Results of the research showed that the journal articles of international journals have higher mean scores of lexical complexity indices than the national, but significant differences only occurred in the indices for the lexical sophistication and lexical variation, particularly the type-token ratio and verb variation. This may show the performance gap between the two publications from Indonesian academics as to share the lexical characteristic of the international publication surpass the national.</p><p><em>Studi komparatif ini membahas lexical complexity dari artikel-artikel jurnal yang dihasilkan para penulis Indonesia. Analisis dilakukan terhadap 98 artikel jurnal terbitan nasional dan internasional dengan memakai 25 indeks lexical complexity. Hasil penelitian memperlihatkan bahwa artikel-artikel jurnal terbitan internasional memiliki rerata indeks lexical complexity lebih tinggi dibanding terbitan nasional, namun perbedaan signifikan hanya terdapat pada indeks-indeks lexical sophistication dan lexical variation, terutama pada rasio type-token dan verb variation. Hal ini bisa jadi merefleksikan adanya performance gap antara kedua kelompok publikasi yang dihasilkan para akademis Indonesia, sekaligus memperlihatkan bahwa karakteristik leksikal dari publikasi internasional lebih tinggi dibanding publikasi nasional</em></p><p> </p>