bluuebunny/crossref_metadata_2025_split huggingface dataset:
The efficacy of antiparasitic drug in the form of spray based on Flumethrin, Moxidectin and Pyriproxyfen against canine acarosis
Authors: Arisov M. V. , Devyatyarova S. B. 
Published: December 2023

The purpose of the research is to study the efficacy of the drug in the form of spray based on Fipronil, Moxidectin and Pyriproxyfen against canine acarosis.Materials and methods. The assessment of the acaricidal effect of multicomponent drug against canine acarosis was carried out on the basis of the All-Russian Scientific Research Institute of Infectious Diseases (VNIIP), a branch of the Federal State Budgetary Institution FSC VIEV RAS, as well as the veterinary clinic GLOBALVET CLINIC LLC (Moscow) in 2020–2022. 82 dogs were used in the experiments, including those spontaneously infected with Otodectes cynotis (38 sp.), Sarcoptes canis (28 sp.), and Demodex canis (16 sp.). The animals were divided into experimental and control groups. To the infected animals of the experimental groups, the drug was applied in the form of spray to the affected areas of the body at the rate of 1 ml per 10 cm2, 2–4 times with an interval of 7 days. The dogs in the control group were treated at the end of the experiment. The efficacy of the drug was taken into account by examining and recording the number of ticks in animals before and 3, 11, 25, 40 and 60 days after treatment. The results were processed statistically using Microsoft Excel.Results and discussion. On the 11th day, all animals showed extinction of clinical signs, healing of affected skin areas and scratches, and the appearance of new hair in areas of alopecia; microscopy of scrapings revealed single mites, deformed larvae and eggs. Microscopy of skin scrapings on the 25th day revealed single mites in 5 dogs affected by demodicosis. On the 40th day, upon examination and acarological examination of animal skin scrapings, no S. canis, O. cynotis and D. canis mites were found. The research results showed 100% efficacy of the drug.
Analisis Faktor-Faktor Yang Mempengaruhi Struktur Modal Di Masa Pandemi Covid-19 Pada Perusahaan Industri Barang Konsumsi Pada Subsektor Farmasi Yang Terdaftar Di Bursa Efek Indonesia
Authors: Oktarina Andini , Valianti Reva M. , Sudiyanto Totok 
Published: December 2023

Tujuan penelitian ini adalah untuk mengetahui faktor-faktor yang berpengaruh terhadap struktur modal pada perusahaan sub sektor farmasi yang terdaftar di Bursa Efek Indonesia periode 2020-2021. Penelitian ini menggunakan variabel struktur aktiva, pertumbuhan perusahaan, likuiditas dan profutabilitas sebagai variable independen dan struktur modal sebagai variabel dependen. Penelitian ini menggunakan metode sampling Banyaknya sampel yang digunakan dalam penelitian ini berdasarkan kriteria sebanyak 4 perusahaan. Penelitian ini dilakukan pada periode 2020-2021 sehingga diperoleh data observasi sebanyak 32 data observasi. Teknik analisis data yang digunakan adalah Analisis Regresi Linier Berganda dengan program Spss 25.
Hasil analisis data atau hasil regresi menunjukkan bahwa secara simultan struktur aktiva, pertumbuhan perusahaan, likuiditas dan profitabilitas berpengaruh terhadap struktur modal. Sedangkan secara parsial variabel yang berpengaruh signifikan terhadap struktur modal adalah struktur aktiva, likuiditas dan profitabilitas. Sedangkan variabel pertumbuhan perusahaan, tidak berpengaruh signifikan terhadap struktur modal.
Analisis Faktor Yang Mempengaruhi Cash Holding Perusahaan Pertambangan Di BEI Tahun 2019 -2021
Authors: Carlos Pangestu Juan , Margaretha Phebyana 
Published: December 2023

Penelitian ini meneliti terkait faktor – faktor yang mempengaruhi Cash Holding Perusahaan pertambangan di BEI Tahun 2019 – 2021. Pengelolaan kas yang baik oleh manajemen perusahaan maka menunjukkan baiknya kemampuan perusahaan untuk mempertahankan operasionalnya karena Kas merupakan aset perusahaan paling likuid dan penggerak operasional suatu perusahaan. Jumlah Kas yang dipegang suatu perusahaan menjadi sangat penting terutama untuk stabilitas operasional perusahaaan. Cash Holding merupakan hal yang penting ketika krisis keuangan melanda dan penelitian terdahulu menunjukkan bahwa jika sebuah perusahaan memiliki kepemilikan kas yang lebih tinggi, kinerja operasinya pulih lebih cepat setelah krisis .Variabel independen dalam penelitian ini adalah Leverage, Cash Flow, Firm Size, ROA dan Likuiditas. Metode penelitian menggunakan uji asumsi klasik, analisis regresi berganda, uji F, Uji t. Hasil menunjukkan bahwa hanya variabel likudiitas yang memiliki pengaruh terhadap Cash holding sedangkan variabel lain (Leverage, Cash Flow, Firm Size, ROA) menunjukkan hasil tidak berpengaruh. nilai Sig F sebesar 0,079 > 0,05 sehingga dapat disimpulkan bahwa secara simultan tidak terdapat pengaruh yang signifikan dari variabel-variabel independen terhadap Cash holding. Perusahaaan yang ingin menjaga Cash holdingnya untuk operasional ataupun hal lainnya harus memperhatikan Likuditas perusahaaannya karena Likuiditas juga digunakan untuk mengukur seberapa mampu perusahaan dalam membayar utang-utangnya. Hal itu tentu menyebabkan Cash yang dihold perusahaan juga semakin besar seiring dengan likuiditas yang tinggi.
PENGARUH UMUR PERUSAHAAN DAN KEPEMILIKAN PUBLIK TERHADAP KETEPATAN WAKTU PELAPORAN KEUANGAN PADA PERUSAHAAN YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2020-2022
Authors: Desma Dwi Purnama  , Sulaeman Sulaeman 
Published: December 2023

ABSTRAK
Penelitian ini bertujuan untuk menguji apakah Umur Perusahaan dan Kepemilikan Publik berpengaruh signifikan terhadap ketepatan waktu pelaporan keuangan pada perusahaan yang terdaftar di Bursa Efek Indonesia (BEI). Penelitian ini menggunakan jenis penelitian deskriptif pendekatan kuantitatif, yang diukur dengan menggunakan metode berbasis regresi logistik. Populasi dari penelitian ini adalah perusahaan yang terdaftar di Bursa Efek Indonesia (BEI). Sampel ditentukan berdasarkan metode purpose sampling, dengan jumlah sampel sebanyak 32 perusahaan sehingga total observasi dalam penelitian ini sebanyak 96 observasi. Data yang digunakan dalam penelitian ini berupa data sekunder. Teknik pengumpulan data menggunakan metoda dokumentasi melalui situs resmi IDX: www.idx.co.id. Pengujian hipotesis dengan menggunakan uji parsial dan uji simultan. Hasil penelitian secara parsial membuktikan bahwa Umur perusahaan dan kepemilikan publik tidak berpengaruh terhadap ketepatan waktu pelaporan keuangan, sedangkan hasil penelitian secara simultan membuktikan bahwa Umur perusahaan dan kepemilikan publik berpengaruh terhadap ketepatan waktu pelaporan keuangan pada perusahaan yang terdaftar di BEI.
Kata Kunci: Ketepatan Waktu, Umur Perusahaan, Kepemilikan Publik.
Perubahan Tarif Ppn Terhadap Minat Beli Masyarakat
Authors: Magdalena Febriani Cristina Susianti , Tampubolon Lambok DR 
Published: December 2023

Percepatan pertumbuhan perekonomian dibutuhkan Indonesia pasca pandemic covid-19. Pemerintah mengesahkan Undang-undang Harmonisasi Peraturan Perpajakan, Undang-undang Nomor 7 tahun 2021, yang salah satunya melakukan perubahan pada tarif PPN. Penelitian ini bertujuan untuk melihat minat beli masyarakat akan kebutuhan pokok, pelengkap, harta tidak bergerak dan kendaraan dengan adanya perubahan tarif PPN. Penelitian ini menggunakan uji Wilcoxon dengan total 51 responden yang bekerja atau memiliki background akuntansi yang diharapkan dapat memahami perpajakan dan perencanaan keuangan pribadi. Hasil penelitian ini menunjukkan bahwa terdapat perbedaan yang signifikan pada minat beli masyarakat untuk sebelum dan sesudah perubahan tarif PPN, terdapat jumlah responden yang menurunkan minat belinya lebih besar dibandingkan yang meningkatkan minat belinya atau tetap bertahan saat terjadi perubahan PPN.
Faktor-Faktor Yang Mempengaruhi Mahasiswa Akuntansi Dalam Pemilihan Karier Menjadi Akuntan Publik Pada Mahasiswa Universitas Buddhi Dharma
Authors: Peng wi  , Yunia Oktari  , Jeni  , Farrid Addy Sumantri  
Published: December 2023

Berbagai faktor seperti pengakuan profesional, lingkungan kerja, pelatihan profesional, dan nilai intristik berpengaruh terhadap pemilihan karier menjadi akuntansi publik. Oleh karena itu, penelitian ini bertujuan untuk memberikan bukti empiris bahwa pengakuan profesional, lingkungan kerja, pelatihan profesional, dan nilai intristik berpengaruh pemilihan karier menjadi akuntan publik. Metode analisis dalam penelitian ini menggunakan jalur dengan pengukuran Partial Least Square (PLS). PLS (nominal, ordinal, interval, rasio), objek yang digunakan adalah mahasiswa akuntansi Fakultas Bisnis Universitas Buddhi Dharma sebanyak 132 sampel. Berdasarkan hasil uji hipotesis didapat bahwa, Pengakuan profesional berpengaruh terhadap pemilihan karier menjadi akuntan publik dengan nilai p value 0.000, Lingkungan kerja tidak berpengaruh terhadap pemilihan karier menjadi akuntansi publik dengan nilai p value 0.358, Pelatihan profesional tidak berpengarih terhadap pemilihan karier menjadi akuntan publik dengan nilai p value 0.679, dan Nilai intristik pekerjaaan berpengaruh terhadap pemilihan karier menjadi akuntan publik dengan nilai p value 0.000.
A relação afetiva com a leitura: memórias de professores
Authors: Galvão Ribeiro Ferreira Eliane Aparecida , Valente Thiago Alves 
Published: December 2023

Na área de Humanidades, sobretudo em Letras, pode causar estranhamento que se realize pesquisa voltada à constituição de banco de dados. Pode-se imaginar, a princípio, que se tenta submeter conceitos complexos como “literatura”, “leitura” e “letramento” a quantificações. Contudo, é preciso notar que a formação desses bancos pode contribuir para a consolidação de redes de pesquisa, com consequente troca de informações e referências, entre pesquisadores das mais diversas e distantes regiões do país. Justamente devido a essa espacialidade diversa, propiciar que as unidades da Federação percebam suas condições de pesquisa e desempenho em determinadas áreas traz elementos significativos para o avanço dos trabalhos científicos e culturais. No caso desta pesquisa, objetivou-se expor sucintamente alguns indícios sobre memórias de leitura de professores da área de Letras, da região conhecida como Norte Pioneiro, do Estado do Paraná e da região limítrofe com aquela, demarcada pelos municípios paulistas de Assis e Ourinhos, no Estado de São Paulo, inscritos em um curso de especialização, que contemplassem obras de literatura juvenil. Palavras-chave: literatura; memória afetiva; especialização; Paraná; São Paulo.
PERCORRENDO AS ÁGUAS DA PENÍNSULA IBÉRICA PELOS SEUS MITOS E MEMÓRIAS
Authors: Vinhal Tatiane Portela 
Published: December 2023

Os mitos e lendas constituem parte da memória de um povo. Uma leitura aprofundada em tais textos permite a compreensão também de uma determinada cultura e suas relações com a natureza, religião e entre seus habitantes. Essa é a proposta do livro Memorias y mitos del agua en la Península Ibérica, de Eloy Martos Núñez e Alberto Martos García, publicado em 2011. Nessa obra os autores realizam um estudo sobre os mitos da Península Ibérica referentes à água. Assim, eles pretendem não só resgatar a memória, como também vivificá-la por meio da leitura das figuras míticas aquáticas. Por isso, a busca pela significação dos mitos é uma das preocupações desses escritores que para alcançarem tal intento se baseiam na hermenêutica.
O CURSO DE PEDAGOGIA: nas representações sociais de estudantes em formação
Authors: Tenório Basílio Márcia Alves , Machado Laeda Bezerra 
Published: December 2023

O objetivo deste artigo é identificar e discutir os elementos gerais, conteúdo de base das representações sociais do curso de Pedagogia entre estudantes em processo formativo. O estudo, de natureza qualitativa, apoiou-se no referencial de Moscovici. Os participantes foram 215 estudantes da UFPE matriculados no referido curso. Utilizamos como procedimento de coleta a associação livre de palavras. A técnica de análise de conteúdo lexical de Bardin (2004) orientou a organização e discussão das evocações. Os resultados revelaram uma representação social polissêmica de Pedagogia centrada nos elementos: educação; formação humana; profissão docente e sua desvalorização; exigências e atributos (teórico, amor, dedicação e vocação). Embora representem o curso como desvalorizado e teórico, os estudantes revelaram que são pessoas melhores, mais preocupadas com o outro, admitem que a formação resgata a humanidade dos sujeitos.
ESTÁGIO CURRICULAR SUPERVISIONADO EM EDUCAÇÃO FÍSICA: QUEM SÃO OS PROFESSORES-COLABORADORES DA EDUCAÇÃO BÁSICA?
Authors: Mazzocato Ana Paula Facco , Krug Hugo Norberto 
Published: December 2023

Este estudo objetivou conhecer e analisar quem são os professores-colaboradores (PC) do Estágio Curricular Supervisionado (ECS) da Universidade Federal de Santa Maria (UFSM). Justificamos a realização desse estudo pela importância de destacar quem são os PC da educação básica no ECS em Educação Física, em especial no CEFD/UFSM. Caracterizamos a metodologia como qualitativa descritiva do tipo estudo de caso. As informações foram obtidas por um questionário e as interpretações das respostas realizadas pela análise de conteúdo. Participaram 22 professores da educação básica que se prontificaram a ser PC. Concluímos que os elementos emergidos permitem inferir que as características pessoais e profissionais dos PC podem e, com certeza, irão influenciar na forma de relacionamento com o seu estagiário e consequentemente nas práticas exercidas. Essa conclusão aponta a necessidade de discussões sobre quem são os PC nos ECS.Palavras-chave: Educação Física. Formação de Professores. Estágio Curricular Supervisionado. Professor-colaborador.
FEATURES OF HIV-INFECTION IN PATIENTS WITH LATE PRESENTATION WHO RECEIVE DTG-BASED ANTIRETROVIRAL THERAPY REGIMENS
Authors: Marchenko O.H. , Stetsenko O.O. , Iziumska O.M. , Pryimenko N.O. , Kotelevska T.M. 
Published: December 2023

Late presentation of HIV-infection is one of the most serious challenges in providing medical care to HIV-infected patients, because delay in detection and treatment of HIV-infection leads to a gradual decrease in the number of CD4+lymphocytes and the threat of infectious complications and tumor processes.
Objective of this study is to find out the features of HIV-infection in people with late presentation of the disease, to evaluate the effectiveness of treatment and factors influencing the emergence of severe opportunistic infections on the background of dolutegravir-based antiretroviral therapy regimens. To achieve this goal, a cohort retrospective study was conducted, during which data from 210 outpatient records were analyzed.
Analysis of opportunistic infections depending on the level of lymphocytes at the time of registration showed that in 123 (58.6%) of 210 late presenters, opportunistic infections were diagnosed at lymphocytes level below 200 cells/mL, in 22 people, while severe opportunistic infections were registered at a lymphocytes level above 500 cells/mL.
Analysis of the clinical effectiveness of antiretroviral therapy showed that while taking the drugs, some patients continued to develop severe opportunistic infections such as tuberculosis, oropharyngeal candidiasis and severe bacterial diseases. An analysis of the Kaplan-Meier survival curve showed that there is a significant relationship between low baseline lymphocytes counts and the development of late opportunistic infections during treatment.
Thus, the majority of HIV-infected patients were diagnosed with wasting syndrome, profound immunosuppression, severe opportunistic infections, and their combination at the time of registration. In some patients, severe late opportunistic infections were diagnosed with a satisfactory lymphocytes count above 500 cells/mL and subsequently on antiretroviral treatment. A low baseline lymphocytes count was identified as a risk factor for the development of severe opportunistic infections on antiretroviral therapy.
PECULIARITIES OF THE COURSE OF HYDROTHORAX IN PATIENTS WITH INFECTIOUS AND SEPTIC COMPLICATIONS OF ACUTE SEVERE PANCREATITIS.
Authors: Cherkun O. Yu. 
Published: December 2023

At present, acute pancreatitis holds the second position in the hierarchy of acute intra-abdominal pathology, with a mortality rate of up to 70% in severe cases. The emergence of reactive hydrothorax at the onset of the disease, as well as during the course of treatment, may signify a severe trajectory of acute pancreatitis, contributing to an elevated fatality rate. The objective of this study is to analyze the progression of reactive hydrothorax in patients experiencing acute severe pancreatitis.
Матеріали і методи. У дослідження включено 127 пацієнтів з тяжким та середньо-тяжким перебігом гострого панкреатиту, віком від 22 до 81 року (в середньому 47,9±14,5 роки), які в переважній більшості госпіталізовані до стаціонару не пізніше 48 годин від початку захворювання. Загалом реактивний гідроторакс було виявлено в дебюті захворювання у 23,6% пацієнтів (переважно за рахунок його лівобічної локалізації – 16,5%), відсоток яких на фоні консервативного лікування та пункцій плевральних порожнин зменшувався до розвитку локальних інфекційно септичних ускладнень черевної порожнини та заочеревинного простору на 12-14 добу перебігу захворювання (підвищення останніх з 15,7% до 22,8%). Встановлено міцний кореляційний зв'язок між появою «другої хвилі» органної дисфункції та рецидиву гідротораксів на другому-третьому тижні від початку захворювання у хворих на гострий тяжкий панкреатит. Показанням до дренування плевральної порожнини було об’єм рідини в ній більше 500 мл, або рецидиви останнього на фоні повторних пункцій плевральної порожнини.
Materials and methods. The study included 127 patients with severe and moderately severe acute pancreatitis aged from 22 to 81 years (mean 47.9±14.5 years), who were mostly admitted to hospital no later than 48 hours after the onset of the disease. In general, reactive hydrothorax detected at the onset of the disease was found in 23.6% of patients (mainly due to its left-sided localisation in 16.5% of cases), the percentage of which decreased the under conservative treatment and pleural punctures to the development of local infectious and septic complications of the abdominal cavity and retroperitoneal space on day 12-14 of the disease (increase from 15.7% to 22.8%). The study has revealed a strong correlation between the appearance of the "second wave" of organ dysfunction and the recurrence of hydrothorax in the second or third week after the onset of the disease in patients with acute severe pancreatitis. Indications for pleural cavity drainage include fluid volume of more than 500 ml or recurrence of the latter under repeated pleural punctures.
CHARACTERISTICS OF PANCREATIC EXOCRINE FUNCTION IN PREMATURE INFANTS WITH PERINATAL PATHOLOGY
Authors: Dronyk T.A. , Hodovanets Yu.D. 
Published: December 2023

Introduction. According to the World Health Organization (WHO), the incidence of preterm birth is 10-15%, demonstrating with a consistent upward trajectory. Preterm infants exhibit immature and limited exocrine function of the pancreas during the first weeks of life that impedes enteral feeding and leads to the development of malnutrition and malabsorption.
The aim of this study is to investigate the indicators of pancreatic exocrine function in premature infants with perinatal pathology. Materials and methods. The study included 91 premature infants with clinical manifestations of moderate and severe perinatal pathology with signs of disorders of the functional state of the digestive system (group I, gestational age 29 (0/7) - 36 (6/7) weeks) and 57 generally healthy newborns (group II, gestational age 35 (0/7) - 36 (6/7) weeks). The list of laboratory parameters characterizing the functional state of the pancreas in newborns includes: trypsin, amylase and lipase activity in blood serum. Statistical processing of data was performed using the software “STATISTICA” (StatSoft Inc., USA, version 10), program MedCalc (https://www.medcalc. org/index.php). Comparison of quantitative indicators with normal distribution was performed using Student’s t-test. The difference in parameters was considered statistically significant at p<0.05. Results. Newborns of group I had clinical signs of food intolerance including weakened or absence of sucking reflex, regurgitation, stasis, intestinal paresis with delayed meconium and transitional stools, flatulence. Indicators of exocrine pancreatic function in newborns of the experimental group showed a decrease in the activity of trypsin, lipase, and amylase in blood serum compared with those in children of the control group. Conclusions. Clinical signs of dysfunction of digestive system in newborns are characterized by weakened or absence of sucking reflex, regurgitation, intestinal stasis and paresis, delayed passage of meconium and transitional stools, flatulence. Low activity of pancreatic enzymes in blood serum in the presence of gastrointestinal disorders confirms the primary exocrine pancreatic insufficiency, which impairs the assimilation of food ingredients in prematurely infants.
ANALYSIS OF MORBIDITY AMONG EXTREMELY PREMATURE CHILDREN AT EARLY AGE
Authors: Kozakevich V. K. , Kozakevich Е. B. , Zyuzina L.S. , Hasiuk N. І. , Melashchenko О.І. 
Published: December 2023

Introduction. The state of health of prematurely born children is an important medical and social concern. Today, the number of premature babies is increasing all over the world. According to the World Health Organization, about 15 million children are born prematurely every year. About 80% of children are born with a particular pathology. Premature infants are a special group of pediatric patients, who necessitate prompt diagnosis and intervention.
The purpose of this study was to investigate the morbidity rates among patients in the intensive care unit born with very low and extremely low body weight.
Materials and methods. The results of the clinical observation of 178 premature newborns, who were born with a body weight less than 1500 g, are presented. Somatic diseases and disabling pathology experienced by the child during the first three years of life were examined.
Results. The data we received show that almost 50% of babies are discharged from obstetric hospitals with anemia, in the next six months the number of children with anemia reached approximately 60%. We found that iron deficiency in the post-neonatal period correlates with the formation of remote neurological disorders in children born with a body weight less than 1500 g. Diseases of the nervous system play a predominant role in the spectrum of health issues affecting premature infants. This emphasizes the need for ongoing enhancements in diagnostic methods and timely interventions to improve the prognosis for their future development.
Conclusions. The emergence of neurological complications in the long-term for very-low-birth-weight infants is closely tied to critical conditions during the perinatal and neonatal periods. This underscores the importance of considering these factors in the planning and implementation of preventive and therapeutic measures. The efficacy of follow-up observations for this cohort of children is heightened through the application of early intervention methods. Early intervention ensures the prompt identification and correction of adverse consequences stemming from premature birth in accordance with contemporary standards.