bluuebunny/crossref_metadata_2025_split huggingface dataset:
Configurations of actual and perceived motor competence among elementary school children in China: differences in physical activity
Authors: Chai Hongqin , Xue Rui , Yao Lei , Miao Miao , Han Bochen 
Published: December 2023

BackgroundActual motor competence (AMC) and perceived motor competence (PMC), as determinants of children’s active participation in physical activity (PA), were important for children’s healthy development. The correlation between the two had been confirmed. To further understand this relationship, this study investigated the current status of AMC, PMC, and PA in Chinese school-age children, used a person-centered approach to reveal the characteristics of the development of motor competence (MC) in Chinese school-age children and the differences in the level of PA among different MC profiles of children.Materials and methodsA total of 532 children (age: M = 9.37, SD = 1.80 years-old) from grades 1 to 6 participated in this cross-sectional study (male, n = 284, 53.4%; female, n = 248, 46.6%). The Test of Gross Motor Development-3 (TGMD-3) was used to measure children’s AMC, the Pictorial Scale of Perceived Movement Skill Competence (PMSC) to measure children’s PMC, and the revised Chinese version of Physical Activity Questionnaire for Older Children (PAQ-C) to assess children’s PA levels.ResultsThere were some gender differences in AMC but no significant gender differences in PMC and PA in children. AMC and PA levels increased as the children aged, while PMC showed some decline. Cluster analysis identified four groups of children with different MC profiles. Two groups of children had corresponding AMC and PMC levels (the “high-high” cluster, N = 200, 38.91%; the “low-low” cluster, N = 63, 12.26%), and the other two groups were inconsistent in AMC and PMC (the “high-low” cluster, N = 100, 19.46%; the “low-high” cluster, N = 151, 29.38%). Significant differences in PA levels were found between children with different MC profiles. The “high-high” cluster children had the highest PA levels, whereas the “low-low” cluster children demonstrated the lowest PA levels.ConclusionAMC, PMC, and PA in Chinese school-age children were consistent with the pattern of child growth and development. Children with high AMC and high PMC usually had high levels of PA. Therefore, it was recommended to seize the best opportunity to intervene with children, and family, school, and community should synergize to help children improve AMC and PMC, and then actively participate in PA.
Pharmacoeconomic evaluation of isavuconazole, posaconazole, and voriconazole for the treatment of invasive mold diseases in hematological patients: initial therapy prior to pathogen differential diagnosis in China
Authors: Han Guangxin , Xu Qing , Lv Qianzhou , Li Xiaoyu , Shi Xiaoping 
Published: December 2023

BackgroundInvasive mold diseases (IMD) is associated with high mortality and a substantial economic burden. For high-risk patients, fever drive or diagnostic drive therapy is usually initiated prior to the differential diagnosis of the pathogen. This study evaluated the cost-effectiveness of isavuconazole, posaconazole, vs. voriconazole in the treatment of IMD from the perspective of the Chinese healthcare system, informing healthcare decision-making and resource allocation.MethodsA decision analytic model was constructed using TreeAge Pro 2011 software to evaluate the cost-effectiveness of the entire disease course. We assumed that the prevalence of mucormycosis in the patients entering the model was 7.8%. Efficacy, cost, adverse events, and other data included in the model were mainly derived from clinical studies, published literature, and publicly available databases. The primary outcomes of the model output were total cost, quality-adjusted life years (QALYs), life years (Lys), and incremental cost-effectiveness ratio (ICER). The willing-to-pay (WTP) threshold was defined as one to three times China's GDP per capita in 2022. One-way sensitivity analysis and probability sensitivity analysis were used to determine the robustness of the model. At the same time, the cost-effectiveness of three triazole antifungal agents under a broader range of mucormycosis prevalence, when voriconazole was covered by medical insurance reimbursement, and after the price reduction of posaconazole was discussed.ResultsCompared with voriconazole, isavuconazole provided an additional 0.38 Lys (9.29 vs. 8.91 LYs) and 0.31 QALYs (7.62 vs. 7.31 QALYs); ICER was $15,702.46/QALY, well-below the WTP threshold ($38,223/QALY). However, posaconazole did not provide a significant economic advantage over voriconazole (9.40 vs. 9.36 Lys; 7.71 vs. 7.68 QALYs; ICER $64,466.57/QALY). One-way sensitivity analysis found that ICER was highly sensitive to the mortality of patients with invasive aspergillus infection. In the probabilistic sensitivity analysis, when the WTP threshold was $38,223/QALY, the probability of isavuconazole being cost-effective was 72.9%. The scenario analysis results indicated that posaconazole would become cost-effective when the price was reduced by 15% or the prevalence of mucormycosis was 14%.ConclusionsIsavuconazole represents a cost-effective initial option for treating IMD in high-risk hematological patients prior to the differential diagnosis of pathogens. It will also be economical when a 15% reduction in posaconazole cost is achieved.
Molecular epidemiology of SARS-CoV-2 in Northern South Africa: wastewater surveillance from January 2021 to May 2022
Authors: Tambe Lisa Arrah Mbang , Mathobo Phindulo , Matume Nontokozo D. , Munzhedzi Mukhethwa , Edokpayi Joshua Nosa , Viraragavan Amsha , Glanzmann Brigitte , Tebit Denis M. , Mavhandu-Ramarumo Lufuno Grace , Street Renee , Johnson Rabia , Kinnear Craig , Bessong Pascal Obong 
Published: December 2023

IntroductionWastewater-based genomic surveillance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) provides a comprehensive approach to characterize evolutionary patterns and distribution of viral types in a population. This study documents the molecular epidemiology of SARS-CoV-2, in Northern South Africa, from January 2021 to May 2022.MethodologyA total of 487 wastewater samples were collected from the influent of eight wastewater treatment facilities and tested for SARS-CoV-2 RNA using quantitative reverse transcriptase polymerase chain reaction (qRT-PCR). SARS-CoV-2 positive samples with genome copies/mL ≥1,500 were subjected to allele-specific genotyping (ASG) targeting the Spike protein; 75 SARS-CoV-2 positive samples were subjected to whole genome sequencing (WGS) on the ATOPlex platform. Variants of concern (VoC) and lineages were assigned using the Nextclade and PangoLIN Software. Concordance for VoC between ASG and WGS analyses was determined. Sequence relationship was determined by phylogenetic analysis.ResultsSeventy-five percent (365/487) of the influent samples were positive for SARS-CoV-2 RNA. Delta and Omicron VoC were more predominant at a prevalence of 45 and 32%, respectively, and they were detected as early as January and February 2021, while Beta VoC was least detected at a prevalence of 5%. A total of 11/60 (18%) sequences were assigned lineages and clades only, but not a specific VoC name. Phylogenetic analysis was used to investigate the relationship of these sequences to other study sequences, and further characterize them. Concordance in variant assignment between ASG and WGS was seen in 51.2% of the study sequences. There was more intra-variant diversity among Beta VoC sequences; mutation E484K was absent. Three previously undescribed mutations (A361S, V327I, D427Y) were seen in Delta VoC.Discussion and ConclusionThe detection of Delta and Omicron VoCs in study sites earlier in the outbreak than has been reported in other regions of South Africa highlights the importance of population-based approaches over individual sample-based approaches in genomic surveillance. Inclusion of non-Spike protein targets could improve the specificity of ASG, since all VoCs share similar Spike protein mutations. Finally, continuous molecular epidemiology with the application of sensitive technologies such as next generation sequencing (NGS) is necessary for the documentation of mutations whose implications when further investigated could enhance diagnostics, and vaccine development efforts.
The factors that influence the growth and performance of micro and small-scale enterprises in Dessie Town administration
Authors: Ebrahim Endris Assen , Toy Ahmet , Kassim Yissa Hassen 
Published: December 2023

IntroductionThe growth or performance of Micro and Small-Scale Enterprises (MSSEs) is widely recognized for their important contributions to economic developments in developing countries. Small and Medium-sized businesses (MMEs) in most developing nations encounter obstacles throughout and after the start-up process. This research aims to explore the determinants of the growth of MSSEs with a special emphasis on five work sectors: manufacturing, trade, construction, service, and urban agriculture in Dessie Town, Ethiopia.MethodsThe primary data was collected using a self-questionnaire from a sample of 218 managers/owners of MSE operators. Both descriptive and inferential analysis were used to analyze the collected data. Descriptive narrations were used to analyze qualitative data as a concurrent triangulation strategy. The sample respondents were selected using a stratified random sampling method based on the type of business sector. This practical study provoked nine major issues affecting the growth of MSSEs in town: political &amp; legal factors, including bureaucratic bottlenecks system, the COVID-19 pandemic, working premises, market-related issues, road infrastructures, management system, technology-related factors, and entrepreneurial-related factors. The results show that linear and positive substantial to strong significant relationships or associations exist between some independent variables and the growth of MSSEs. Among the expected nine determinants of MSSEs' growth and performance, only political &amp; legal-related, management-related, market-related, technology-related, infrastructure-related, entrepreneur-related factors, and COVID-19 pandemic were statistically significant. Besides, the nominated factors explained the total variations in the MSSEs' growth and performance at a 5% significance level. Realizing this conclusion, the government and non-government bodies and operators of MSSEs should give attention to management, marketing, technology infrastructure, and entrepreneur-related factors.
Cognitive behavioral therapy for insomnia in a military traumatic brain injury clinic: a quality improvement project assessing the integration of a smartphone application with behavioral treatment
Authors: Matsuura Justin T. , Keller Nicole S. , Lustik Michael B. , Campbell Carmen E. , Grills Chad E. 
Published: December 2023

ObjectivesWhile the association between insomnia and traumatic brain injury (TBI) is well established, TBI rehabilitation programs that focus on sleep as a primary target are limited. Cognitive behavioral therapy for insomnia (CBTi) is an effective treatment for insomnia, however; its use within TBI clinics is relatively unknown. Therefore, our aim was to evaluate the implementation of CBTi, used in conjunction with a smartphone app for insomnia, within a US military TBI program to improve care within this setting.SettingA TBI clinic at a US military installation.MethodsMHS beneficiaries underwent 6 sessions of CBTi and a 1-month post-treatment follow up session. Data was collected at each treatment session as part of routine clinical care.ResultsA total of 69 US MHS beneficiaries seen at a TBI clinic with a diagnosis of insomnia began CBTi. Attrition rate at the end of the CBTi program and 1-month posttreatment session was 35% and 48%, respectively. Results demonstrated that sleep onset latency (SOL) and wake after sleep onset (WASO) decreased during treatment (p's &lt; 0.001). Further, symptoms reported on the Insomnia Severity Index (ISI) improved during CBTi (p &lt; 0.001).ConclusionFindings demonstrate how CBTi used in conjunction with a CBTi smartphone application can be used to effectively treat insomnia for MHS beneficiaries seeking care for TBIs. This evaluation provides the basis for further research on how CBTi may improve care within TBI programs.
Quantification of run-of-river hydropower potential in the Upper Indus basin under climate change
Authors: Dhaubanjar Sanita , Lutz Arthur F. , Smolenaars Wouter Julius , Khanal Sonu , Jamil Muhammad Khalid , Biemans Hester , Ludwig Fulco , Shrestha Arun Bhakta , Immerzeel Walter W. 
Published: December 2023

IntroductionDespite ambitious plans to quadruple hydropower generation in the Indus basin, a quantitative assessment of the impact of climate change on hydropower availability in the basin is missing. To address this gap, we combine downscaled CMIP6 projections with the Hydropower Potential Exploration (HyPE) model to quantify future hydropower potential available in the upper Indus basin.MethodsHyPE uses a spatial cost-minimization framework to evaluate four classes of hydropower potential, namely theoretical, technical, financial and sustainable, considering various constraints on the siting and sizing of two run-of-river hydropower plant configurations.ResultsUnder future discharge projections, all classes of potential increase while subbasin changes align with the spatial patterns projected in hydro-climatology. Theoretical potential changes by 3.9–56 %, technical potential by −2.3–46.8 %, financial potential by −8.8–50.4 % and sustainable potential by −6.1–49.7 %. A small decline is observed in the northwestern subbasins where increase in potential is lower than in the southeast. In contrast, with increasing variability in the Indian Summer Monsoon in the future, the southeastern subbasins have the strongest increase in sustainable potential accompanied by higher increase in plant size, decrease in costs and higher variability. The southeastern Satluj subbasin is the hotspot where sustainable potential has the highest increase of up to 145 %. The northwestern Kabul subbasin has the highest decrease of up to −27 %. The Swat subbasin has the lowest variability in sustainable potential while the Jhelum and Indus main subbasins remain the subbasins with the cheapest potential into the future. The performance of future sustainable portfolios differ from the performance of historical portfolios by −11.1–39.9 %.DiscussionHence, considering future climate in the present-day planning of hydropower will lead to improved performance under a majority of scenarios. The sufficiency of hydropower potential to fulfill energy security depends on future population growth. Energy availability is projected to decline in the northwest as population increases faster than hydropower potential. The per capita sustainable potential In the Kabul subbasin reduces to a third of the historical value. A socio-hydrological approach is necessary to address the complexity of achieving sustainable and equitable hydropower development in the Indus basin under such spatial mismatch between hydropower availability and energy demand in a resource-limited world.
Crane-powered pectus excavatum repair: the NeoPectus surgery
Authors: Park Hyung Joo , Rim Gongmin , Yoon Seung Keun 
Published: December 2023

IntroductionThe conventional technique for pectus excavatum repair was pushing up the depressed chest wall by turning over the convexity of the bent pectus bar. We developed a new concept in which a total crane lift was used as the source of power to elevate the depressed sternum without using pectus bar leverage. This study aims to verify the efficacy of exclusively crane-powered pectus excavatum repair in recent years.MethodsAmong the 3622 pectus deformity repairs since 1999, 691 cases repaired with the total crane power between 2017 and 2022 were enrolled. The mean age was 12.0 years (3–45). The operative technique involved wire/screw crane elevation of the sternum, the entire chest wall remodeling with the cross or parallel bars, the bridge/claw bar fixations, and other adjunctive techniques. Outcome analysis included morphological variations, patterns of pectus bar placement, and complication rates.ResultsThe crane technique and pectoscopy (100%) were used. The bar placements were parallel (22.0%) and cross-bar (47.5%). The bar fixations were the claw fixators for a single bar (30.5%) and the bridge plates for multiple bars (69.5%). The flare-buster and magic strings were liberally used. No serious complications or catastrophic events occurred, but minor complications occurred in 16.9%: pneumothorax in 7.4% (51), pleural effusion in 1.6% (11), and wound problems in 0.4% (3). There was no case of bar displacement.DiscussionThe crane-powered pectus excavatum repair showed excellent results with minimal complications and no bar displacement. This innovative approach, part of the NeoPectus surgery, represents a significant advancement in correcting pectus excavatum deformities by utilizing a crane machine to elevate the chest wall.
Estudio de métodos para incrementar la productividad en la curtiembre Industrias Herpami EIRL
Authors: Palma Mejía Luis Roli , Quiroz Flores Percy Alex , Robles Lora Marcos Alejandro 
Published: December 2023

El mal desempeño de los operarios impacta en la productividad de la empresa, lo que a su vez afecta la rentabilidad, por ello es fundamental un estudio de métodos en las industrias. El objetivo fue implementar un estudio de método para aumentar la productividad en la curtiembre Industrias Herpami EIRL. Bajo una investigación aplicada con un diseño experimental del tipo pre-experimental. La población estuvo conformada por datos de la productividad correspondiente a los meses de enero a mayo del 2022. Se empleó como técnica la observación y análisis documental, apoyado con la guía de observación y matriz de análisis como instrumento. Se determinó que el índice combinado de productividad para los meses de abril y mayo fue de 3.58 incrementándose en 0.79 soles en relación a los meses de enero y febrero´. Se concluye que gracias a la implementación de un estudio de método aumentó la productividad de la materia prima, como de la mano de obra.
COMMUNITY EMPOWERMENT THROUGH TRAINING AND ASSISTANCE OF LOCAL MATERIAL APPLIED TECHNOLOGY AND ENTREPRENEURSHIP
Authors: Fauziyah Roro Nur , Syarief Osman , Gumilar Mulus , Agustina Nina 
Published: December 2023

Background : The problem of poverty is a complex matter involving various aspects such as the fulfillment of food, health, education, employment and so on. Data from the Central Statistics Agency in 2014 shows that poverty rates are still high in Indonesia, which is around 13.8% in rural areas and 8.2% in urban areas. Poverty has a relationship with community welfare and health problems, including problems with the nutritional status of children under five.According to data from the Basic Health Research (Riskesdas) of the Ministry of Health of the Republic of Indonesia in 2013, 19.6% of children under five in Indonesia suffer from malnutrition and malnutrition. One of the long-term indicators for chronic malnutrition in children is childhood stunting. In 2013 in Indonesia as many as 37.3% of children under five, which is about 9 million children under five are short and very short. The efforts made according to this approach are to encourage an entrepreneurial culture, and encourage the emergence of small businesses, as well as encourage individual participation so that they can optimally utilize the entrepreneurial culture and the created business climate. One of the entrepreneurship is the production of black sticky rice tape. The biggest producer of black sticky rice tape in West Java Province is West Bandung Regency. Black sticky rice tape is a food that contains anthocyanins and has antioxidant activity and fiber.
Methods : Community service is carried out in West Bandung Regency, Cililin sub-district, Kidan Pananjung Village because it is the location of a large black glutinous tape producer center in West Java and in this location research has been carried out related to the consumption of black sticky rice tape in the prevention of non-communicable diseases, namely metabolic syndrome and One of the recommendations of the research results is community development.Based on the above, it is necessary to do community service, namely: Community Empowerment through Training and Assistance in Applied Technology of Local Materials and Entrepreneurship to Cadres in Cililin District, West Bandung Regency.
Results : The data from the pretest-posttest results of the effect of technology training on processed glutinous rice products in an effort to increase entrepreneurial abilities in Kidang Pananjung Village, Cililin District, West Bandung.
Conclusion : Community Empowerment through Training and Assistance in Applied Technology of Local Materials and Entrepreneurship to Cadres in Cililin District is necessary to aplly.
RESPON PERTUMBUHAN TANAMAN JERUK SIAM BANJAR (Citrus reticulata) PADA MEDIA YANG DI CAMPUR DENGAN LIMBAH ENDAPAN SAGU
Authors: Rahmawati Linda , Lukmana Mila , Iswahyudi Herry , Asfia Asfia 
Published: December 2023

Limbah sagu merupakan ampas empulur sagu yang telah diambil patinya. Limbah padat industri sagu yang telah menyebabkan pengaruh terhadap dilingkungan sekitar,sehingga dimanfaatkan untuk menjadi limbah organik yang kaya akan bahan organik yang dapat dijadikan sebagai pupuk.Saat ini, tanaman jeruk siam banjar merupakan tanaman uji coba di Desa Sungai Habaya kabupaten Barito Kuala, dalam media tanam dengan polibag. Tanaman jeruk siam banjar biasanya ditanam dalam suatu lahan atau wilayah perkebunan. dalam penelitian ini dijadikan kontrol (perlakuan P0). Dalam penelitian ini limbah sagu diberikan ke tanaman jeruk siam dengan perlakuan (P1,dengan limbah 200 g/polibag. P2,limbah 250 g/polibag dan P3,limbah 300 g/polybag ). Nutrisi yang diperoleh jeruk siam banjar hanya diperoleh dari kandungan media tanam. Berdasarkan hasil pengamatan menunjukkan adanya pemberian limbah sagu pada tanaman terhadap tinggi tanaman dan jumlah daun pada tanaman jeruk. Hasil pengamatan menunjukkan pertambahan tinggi tanaman jeruk siam banjar pada perlakuan P3 (limbah sagu 300 g/polibag )memperoleh hasil terbaik Dengan pertambahan tinggi 22,7 CM, dibandingkan dengan P1,P2, dan kontrol yaitu dengan perbedaan P1,16,7 CM, P2, 16,7 CM dan control 13,7 CM pada pertambahan tinggi tanaman,dan pada pertambahan jumlah daun juga hasil terbaiknya didapatkan oleh P2 dan P3 yaitu dengan jumlah P2,72 helai daun dan P3,78 helai daun selama 1,5 bulan dalam masa pengamatan dengan perbandinga pada P1, dan control yaitu P1,23,7 helai daun dan control 15,7 helai daun yang tumbuh selama masa vegetatif, dalam penelitian ini dapat disimpulkan Respon pertumbuhan pohon jeruk setelah diberi limbah sagu, yaitu semakin tinggi dosis yang diberikan,pertambahan tinggi dan jumlah daun semakin meningkat.