bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of previous administration of potassium iodine and different durations of low iodine diets for radioiodine therapy on the treatment of Graves' disease in iodine-rich areas
Authors: Tamura Mika , Nakada Kunihiro , Iwanaga Haruna , Fujita Naotoshi , Kato Katsuhiko 
Published: November 2023

Abstract
Purpose
To examine whether adherence to a low-iodine diet (LID) enhances the therapeutic efficacy of radioiodine therapy (RAI) in Graves’ hyperthyroidism (GH) in iodine-rich areas.

Methods
We retrospectively evaluated 185 patients with GH from Aichi (n = 114) and Hokkaido (n = 71) Prefectures. Patients aged ≥ 18 years with GH who underwent RAI between December 2012 and March 2022 were divided into subgroups based on pretreatment with anti-thyroid drug (ATD) or potassium iodide (KI). Patients were followed up with LID from 18 days (group A) or 7 days (group H) before RAI to 3 days after RAI. The dose of radioactive iodine 131 (131I) was adjusted to deliver > 100 Gy to the thyroid. The associations between urinary iodine concentration on UIC2 vs. 24hRU and UIC2 vs. the 1-year RAI success rate (SR) were investigated.

Results
Compared with UIC1, UIC2 was significantly decreased in all subgroups (P < 0.01). An inverse correlation between UIC2 and 24hRU was observed in the four groups; however, the difference was insignificant. The SR in groups A and H was 85% and 89%, respectively. Univariate analysis revealed no association between UIC2 and SR in each group. Additionally, stratification of the 185 patients into quartiles using UIC2 yielded no significant differences in SR (p = 0.79).

Conclusions
LID sufficiently reduced UIC in patients undergoing RAI. Although a lower UIC2 may increase 24hRU, it did not increase the success of RAI. The benefit of LID in enhancing the efficacy of RAI in GH treatment remains uncertain.
Internistische Abklärung bei retinalen Gefäßverschlüssen
Authors: Feltgen Nicolas , Ochmann Tabea , Hoerauf Hans 
Published: November 2023

ZusammenfassungRetinale Gefäßverschlüsse erfordern eine enge Kooperation der medizinischen Fächer, um eine optimale Betreuung der Betroffenen sicherzustellen. Dabei unterscheidet sich die internistische Abklärung zwischen den arteriellen und venösen Verschlüssen kaum, bei den retinalen Arterienverschlüssen sollte sie aber unmittelbar erfolgen. Die wichtigsten assoziierten Diagnosen sind arterielle Hypertonie, Diabetes mellitus, Fettstoffwechselstörung und Vorhofflimmern. Bei jüngeren Patienten und bei fehlenden Risikofaktoren sollte nach selteneren Ursachen gesucht und insbesondere eine Riesenzellarteriitis ausgeschlossen werden. Bei beiden Verschlussarten muss auch an ein verursachendes Glaukom gedacht werden.
Trace element partitioning in basaltic systems as a function of oxygen fugacity
Authors: Leuthold J. , Blundy J. , Ulmer P. 
Published: November 2023

AbstractAlong with temperature, pressure and melt chemistry, magmatic oxygen fugacity (fO2) has an important influence on liquid and solid differentiation trends and melt structure. To explore the effect of redox conditions on mineral stability and mineral-melt partitioning in basaltic systems we performed equilibrium, one-atmosphere experiments on a picrite at 1200–1110 °C with fO2 ranging from NNO-4 log units to air. Clinopyroxene crystallizes from 1180 °C to near-solidus, along with plagioclase, olivine and spinel. Olivine Mg# increases with increasing fO2, eventually reacting to pigeonite. Spinel is absent under strongly reducing conditions. Mineral-melt partition coefficients (D) of redox-sensitive elements (Cr, Eu, V, Fe) vary systematically with fO2 and, in some cases, temperature (e.g. DCr in clinopyroxene). Clinopyroxene sector zoning is common; sectors along a- and b-axes have higher AlIV, AlVI, Cr and Ti and lower Mg than c-axis sectors. In terms of coupled substitutions, clinopyroxene CaTs (MgSi = AlVIAlIV) prevails under oxidized conditions (≥ NNO), where Fe3+ balances the charge, but is limited under reduced conditions. Overall, AlIV is maximised under high temperature, oxidizing conditions and in slowly grown (a–b) sectors. High AlIV facilitates incorporation of REE (REEAlIV = CaSi), but DREE (except DEu) show no systematic dependence on fO2 across the experimental suite. In sector zoned clinopyroxenes enrichment in REE3+ in Al-rich sectors is quantitatively consistent with the greater availability of suitably-charged M2 lattice sites and the electrostatic energy penalty required to insert REE3+ onto unsuitably-charged M2 sites. By combining our experimental results with published data, we explore the potential for trace element oxybarometry. We show that olivine-melt DV, clinopyroxene-melt DV/DSc and plagioclase-melt DEu/DSr all have potential as oxybarometers and we present expressions for these as a function of fO2 relative to NNO. The crystal chemical sensitivity of heterovalent cation incorporation into clinopyroxene and the melt compositional sensitivity of the Eu2+–Eu3+ redox potential limit the use of clinopyroxene-melt and plagioclase-melt, however, olivine-melt DV affords considerable precision and accuracy as an oxybarometer that is independent of temperature, and crystal and melt composition. Variation of DV and DV/DSc with fO2 for olivine and clinopyroxene contains information on redox speciation of V in coexisting melt. By comparing the redox speciation constraints from partitioning to data from Fe-free synthetic systems and XANES spectroscopy of quenched glasses, we show that homogenous equilibria involving Fe and V species modify V speciation on quench, leading to a net overall reduction in the average vanadium valence. Mineral-melt partitioning of polyvalent species can be a useful probe of redox speciation in Fe-bearing systems that is unaffected by quench effects.
Malpractice claims after antireflux surgery and paraesophageal hernia repair: a population-based analysis
Authors: Nurminen Nelli M. J. , Järvinen Tommi K. M. , Kytö Ville J. , Salo Silja A. S. , Egan Caitlin E. , Andersson Saana E. , Räsänen Jari V. , Ilonen Ilkka K. P. 
Published: November 2023

Abstract
Background
The complication rate of modern antireflux surgery or paraesophageal hernia repair is unknown, and previous estimates have been extrapolated from institutional cohorts.

Methods
A population-based retrospective cohort study of patient injury cases involving antireflux surgery and paraesophageal hernia repair from the Finnish National Patient Injury Centre (PIC) register between Jan 2010 and Dec 2020. Additionally, the baseline data of all the patients who underwent antireflux and paraesophageal hernia operations between Jan 2010 and Dec 2018 were collected from the Finnish national care register.

Results
During the study period, 5734 operations were performed, and the mean age of the patients was 54.9 ± 14.7 years, with 59.3% (n = 3402) being women. Out of all operations, 341 (5.9%) were revision antireflux or paraesophageal hernia repair procedures. Antireflux surgery was the primary operation for 79.9% (n = 4384) of patients, and paraesophageal hernia repair was the primary operation for 20.1% (n = 1101) of patients. A total of 92.5% (5302) of all the operations were laparoscopic. From 2010 to 2020, 60 patient injury claims were identified, with half (50.0%) of the claims being related to paraesophageal hernia repair. One of the claims was made due to an injury that resulted in a patient's death (1.7%). The mean Comprehensive Complication Index scores were 35.9 (± 20.7) and 47.6 (± 20.8) (p = 0.033) for antireflux surgery and paraesophageal hernia repair, respectively. Eleven (18.3%) of the claims pertained to redo surgery.

Conclusions
The rate of antireflux surgery has diminished and the rate of paraesophageal hernia repair has risen in Finland during the era of minimally invasive surgery. Claims to the PIC remain rare, but claims regarding paraesophageal hernia repairs and redo surgery are overrepresented. Additionally, paraesophageal hernia repair is associated with more serious complications.
Reliability of artificial intelligence in predicting total knee arthroplasty component sizes: a systematic review
Authors: Salman Loay A. , Khatkar Harman , Al-Ani Abdallah , Alzobi Osama Z. , Abudalou Abedallah , Hatnouly Ashraf T. , Ahmed Ghalib , Hameed Shamsi , AlAteeq Aldosari Mohamed 
Published: November 2023

Abstract
Purpose
This systematic review aimed to investigate the reliability of AI predictive models of intraoperative implant sizing in total knee arthroplasty (TKA).

Methods
Four databases were searched from inception till July 2023 for original studies that studied the reliability of AI prediction in TKA. The primary outcome was the accuracy ± 1 size. This review was conducted per PRISMA guidelines, and the risk of bias was assessed using the MINORS criteria.

Results
A total of four observational studies comprised of at least 34,547 patients were included in this review. A mean MINORS score of 11 out of 16 was assigned to the review. All included studies were published between 2021 and 2022, with a total of nine different AI algorithms reported. Among these AI models, the accuracy of TKA femoral component sizing prediction ranged from 88.3 to 99.7% within a deviation of one size, while tibial component sizing exhibited an accuracy ranging from 90 to 99.9% ± 1 size.

Conclusion
This study demonstrated the potential of AI as a valuable complement for planning TKA, exhibiting a satisfactory level of reliability in predicting TKA implant sizes. This predictive accuracy is comparable to that of the manual and digital templating techniques currently documented in the literature. However, future research is imperative to assess the impact of AI on patient care and cost-effectiveness.

Level of evidence III
PROSPERO registration number: CRD42023446868.
Design friction in autonomous drive—exploring transitions between autonomous and manual drive in non-urgent situations
Authors: Bley Jessica , Eriksson Alexander , Johansson Lisa , Wiberg Mikael 
Published: November 2023

AbstractIn the ongoing turn to automation, the growing trend towards the design of conditionally and highly automated vehicles (C/HAV) is evident. In a CAV, the driver no longer needs to partake in the driving. However, the vehicle might send a takeover request (TOR) when the CAV’s system reaches its operational boundaries, i.e. a call for a transition from autonomous to manual drive. Previous research on TORs has focused on the context of urgent situations, e.g. hazards and unpredictable events. Furthermore, it has been noted that drivers’ situation awareness (SA) deteriorates after being in autonomous drive. However, less is known about TORs in non-urgent situations. Motivated by this need, the study explores how design friction can serve as a guiding concept for transferring control between autonomous and manual drive in non-urgent situations to increase situation awareness. Design friction is defined as elements of interactions that steer attention and guides the driver to take informed decisions. The work resulted in prototypes that leveraged design friction as part of a takeover sequence. The proposed design was empirically evaluated in a fixed-base medium-fidelity driving simulator. The results indicated that the level of friction might have been too extensive, as some annoyance was expressed. However, participants claimed to feel calm and aware of their surroundings at the moment of regaining control of the vehicle. This suggests that design friction is a promising tool for guiding concept design to enhance transitions from autonomous to manual drive.
The Telephone Language Screener (TLS): standardization of a novel telephone-based screening test for language impairment
Authors: Aiello Edoardo Nicolò , Pucci Veronica , Diana Lorenzo , Corvaglia Alessia , Niang Aida , Mattiello Silvia , Preti Alice Naomi , Durante Giorgia , Ravelli Adele , Consonni Lucia , Guerra Carolina , Ponti Adriana Delli , Sangalli Gaia , Difonzo Teresa , Scarano Stefano , Perucca Laura , Zago Stefano , Appollonio Ildebrando , Mondini Sara , Bolognini Nadia 
Published: November 2023

Abstract
Background
This study aimed at developing and standardizing the Telephone Language Screener (TLS), a novel, disease-nonspecific, telephone-based screening test for language disorders.

Methods
The TLS was developed in strict pursuance to the current psycholinguistic standards. It comprises nine tasks assessing phonological, lexical-semantic and morpho-syntactic components, as well as an extra Backward Digit Span task. The TLS was administered to 480 healthy participants (HPs), along with the Telephone-based Semantic Verbal Fluency (t-SVF) test and a Telephone-based Composite Language Index (TBCLI), as well as to 37 cerebrovascular/neurodegenerative patients—who also underwent the language subscale of the Telephone Interview for Cognitive Status (TICS-L). An HP subsample was also administered an in-person language battery. Construct validity, factorial structure, internal consistency, test–retest and inter-rater reliability were tested. Norms were derived via Equivalent Scores. The capability of the TLS to discriminate patients from HPs and to identify, among the patient cohort, those with a defective TICS-L, was also examined.

Results
The TLS was underpinned by a mono-component structure and converged with the t-SVF (p < .001), the TBCLI (p < .001) and the in-person language battery (p = .002). It was internally consistent (McDonald’s ω = 0.67) and reliable between raters (ICC = 0.99) and at retest (ICC = 0.83). Age and education, but not sex, were predictors of TLS scores. The TLS optimally discriminated patients from HPs (AUC = 0.80) and successfully identified patients with an impaired TICS-L (AUC = 0.92). In patients, the TLS converged with TICS-L scores (p = 0.016).

Discussion
The TLS is a valid, reliable, normed and clinically feasible telephone-based screener for language impairment.
Noise-Induced Hearing Threshold Shift Correlated with Body Weight and External-Ear Amplification in Chinchilla: a Preliminary Analysis
Authors: Grinn Sarah K. , Trevino Monica , Lobarinas Edward 
Published: November 2023

Abstract
Background
External-ear amplification (EEA) has been shown to vary from 5–19 dB-A in large datasets of pediatric, adolescent, and adult human participants. However, variable EEA is an overlooked characteristic that likely plays a role in individual noise-induced hearing loss (NIHL) susceptibility. A noise exposure varying 5–19 dB-A translates to high-EEA individuals theoretically experiencing 3–4 times greater NIHL risk than low-EEA individuals.

Objective
The purpose of this preliminary analysis was to test the hypothesis that higher EEA is correlated with increased noise-induced threshold shift susceptibility.

Design
Nine chinchillas were exposed to 4-kHz octave-band noise at 89 dB-SPL for 24 h. Auditory brainstem response thresholds were obtained pre-exposure, 24-h post-exposure, and 4-week post-exposure. Relationships between EEA and threshold shift were analyzed.

Results
Open-ear EEA ranged 11–19 dB-SPL, and occluded-ear EEA ranged 10–21 dB-SPL. Higher occluded-ear EEA was correlated with increased NIHL susceptibility (p = 0.04), as was lower body weight (p = 0.01). Male animals exhibited more threshold shift than female animals (p = 0.02), lower body weight than female animals (p = 0.02), and higher occluded-ear EEA (male mean = 18 dB; female mean = 15 dB).

Conclusions
Taken together, increased threshold shift susceptibility was observed in the smallest animals, animals with the highest occluded-ear EEA, and in male animals (which tended to have higher occluded-ear EEA). Given the established relationship between smaller body size and higher occluded-ear EEA, these preliminary results suggest that body size (and occluded-ear EEA; a function of body size) could be a potential, underlying driver of NIHL susceptibility differences, rather than true sex differences.
Grade one single-digit addition strategies as predictors of grade four achievement in mathematics
Authors: Sunde Pernille Bødtker , De Smedt Bert , Verschaffel Lieven , Sunde Peter 
Published: November 2023

AbstractEarly detection of and relevant information on children’s mathematical difficulties is important to initiate targeted teaching and intervention. This study investigated the extent to which strategy use in single-digit addition provides additional predictive information about 61 grade one children’s (6-year-old) mathematical achievement 3 years later that is not available from a standardised mathematics achievement test. Four predictors available in year one (arithmetic strategy use, mathematical achievement, non-verbal reasoning skills and sex) explained 54% of the variation in grade four mathematics achievement. Arithmetic strategy use was the most important single predictor of year four mathematics achievement (R2 = 30%) and explained an additional 12% variation if added to a model comprised by the three other year one predictors. This result suggests that systematically obtained measures of how young children solve single-digit arithmetic problems might provide useful information about their foundational number knowledge, which in turn may reveal how well they achieve later in school.
Surface Measure to Depth (SMeTD): a new low-budget system for 3D water temperature measurements for combining with UAV-based thermal infrared imagery
Authors: Loerke Eva , Pohle Ina , Drummond David , Miller Pauline E. , Geris Josie 
Published: November 2023

AbstractCharacterising spatial patterns in water temperature is important for monitoring aquatic habitats and understanding physical and biogeochemical processes to support environmental management decisions. As freshwater bodies exhibit high spatial and temporal variability, high-resolution 3D temperature data are essential to understand local anomalies. The acquisition of simultaneously high spatial and temporal datasets in the field has so far been limited by costs and/or workload associated with commonly used monitoring systems.We present a new, low-cost, spatially and temporally flexible 3D water temperature monitoring system, Surface Measures to Depth (SMeTD). SMeTD can be used to provide information on the relation of water surface temperature to changes with depth, characterise water temperature in 3D and ground truth remotely sensed thermal infrared data. The systems performance was tested under laboratory conditions and under controlled conditions in the field. This revealed an accuracy comparable to established but more expensive monitoring systems. Field testing of SMeTD involved 1-min data collection of 3D water temperature for a full diurnal cycle in a lake. The 3D temperature patterns were supported by a thermal infrared image of the lakes surface. The field dataset demonstrated higher water temperatures and higher water temperature variation at the surface compared to deeper layers. SMeTD can be used to observe a broad range of hydrological processes in natural and artificial aquatic environments and help to understand processes involved with energy budgets, infiltration, limnology, or groundwater surface water exchange.
Therapeutic potential and possible mechanisms of ginseng for depression associated with COVID-19
Authors: Zhao Fangyi , Zhang Kai , Chen Hongyu , Zhang Tianqi , Zhao Jiayu , Lv Qianyu , Yu Qin , Ruan Mengyu , Cui Ranji , Li Bingjin 
Published: November 2023

AbstractRecently, a global outbreak of COVID-19 has rapidly spread to various national regions. As the number of COVID-19 patients has increased, some of those infected with SARS-CoV-2 have developed a variety of psychiatric symptoms, including depression, cognitive impairment, and fatigue. A distinct storm of inflammatory factors that contribute to the initial disease but also a persistent post-acute phase syndrome has been reported in patients with COVID-19. Neuropsychological symptoms including depression, cognitive impairment, and fatigue are closely related to circulating and local (brain) inflammatory factors. Natural products are currently being examined for their ability to treat numerous complications caused by COVID-19. Among them, ginseng has anti-inflammatory, immune system stimulating, neuroendocrine modulating, and other effects, which may help improve psychiatric symptoms. This review summarizes the basic mechanisms of COVID-19 pneumonia, psychiatric symptoms following coronavirus infections, effects of ginseng on depression, restlessness, and other psychiatric symptoms associated with post-COVID syn-dromes, as well as possible mechanisms underlying these effects.
Sharing a medical decision
Authors: Engelsma Coos 
Published: November 2023

AbstractDuring the last decades, shared decision making (SDM) has become a very popular model for the physician-patient relationship. SDM can refer to a process (making a decision in a shared way) and a product (making a shared decision). In the literature, by far most attention is devoted to the process. In this paper, I investigate the product, wondering what is involved by a medical decision being shared. I argue that the degree to which a decision to implement a medical alternative is shared should be determined by taking into account six considerations: (i) how the physician and the patient rank that alternative, (ii) the individual preference scores the physician and the patient (would) assign to that alternative, (iii) the similarity of the preference scores, (iv) the similarity of the rankings, (v) the total concession size, and (vi) the similarity of the concession sizes. I explain why shared medical decisions are valuable, and sketch implications of the analysis for the physician-patient relationship.
The roles of public libraries in enhancing educational systems and social inclusion in Africa
Authors: Bouaamri Asmaa 
Published: November 2023

AbstractPublic libraries constitute an important part of social life and are crucial for supporting the educational system in any society. However, in many African countries, awareness of the role that public libraries can play in strengthening the social contract is largely unrecognized. This may be partly due to the social background that was/is based on oral tradition, to which libraries can adapt in order to sustain the tradition. In the current era, with the fast advancement of technologies, the library's role has changed from a passive institution to an active one by creating new interactive services and activities. The human right for each and every person to have access to information, education, and knowledge plays a significant role in the inclusion and integration of citizens for their lifelong learning and continuous development. Countries’ development relies on the participation of each citizen, who needs equal opportunities and quality education, including the right to benefit from public institutions such as libraries. Hence, this article explores the roles of public libraries in enhancing educational systems and social inclusion in Africa and provides some of the challenges and obstacles faced in this concern. It also examines some remedies and recommendations that can help strengthen social inclusion, particularly in certain African developing countries, as they aim to support the development of educational systems in isolated areas.