bluuebunny/crossref_metadata_2025_split huggingface dataset:
Early disruptions to syringe services programs during the Russian invasion of Ukraine
Authors: Nikitin Benjamin M. , Bromberg Daniel J. , Pykalo Iryna , Ivasiy Roman , Islam Zahedul , Altice Frederick L. 
Published: November 2023

IntroductionThe widespread HIV epidemic in Ukraine is concentrated among people who inject drugs (PWID), making access to sterile injection paraphernalia (SIP) like sterile needles and syringes a critical method of HIV/AIDS prevention; however, the Russian invasion has threatened to disrupt the operations of syringe services programs (SSPs), creating a risk of HIV outbreaks among PWID.MethodsWe conducted 10 semi-structured interviews with outreach workers from SSPs. Interviews were purposively sampled to cover three prototypic regions of Ukraine: temporarily Russian-controlled, frontline, and destination. Qualitative results from interviews were then compared against a standardized, nationwide harm reduction database.ResultsWe found that the Russian invasion triggered both supply and demand challenges for SSPs. Demand increased for all regions due to client transitions from pharmacies that closed to SSPs, increases in illicit drug use, greater client openness to NGO support, and displacement of clients to destination regions. Supply decreased for all areas (except for remote destination regions) due to battle-related barriers like curfews, roadblocks, and Internet disruptions; diminished deliveries of SIP and funding; and staff displacement. Time series plots of the number of unique clients accessing harm reduction services showed that an initial decrease in service provision occurred at the start of the war but that most regions recovered within several months except for Russian-controlled regions, which continued to provide services to fewer clients relative to previous years.ConclusionTo ensure continued scale-up of SIP and other HIV prevention services, the SyrEx database should be leveraged to serve as a streamlined harm reduction locator that can inform workers and clients of open site locations and other pertinent information.
Mediating effects of workgroup processes on the relationship between nurse turnover and nurse outcomes in hospitals
Authors: Bae Sung-Heui , Kim Suin , Myung Hwasook 
Published: November 2023

BackgroundNurse turnover is often considered to be an outcome, and few studies have investigated its consequences in nursing care. The underlying mechanism of the nurse turnover–nurse outcome relationship has not been empirically investigated. Therefore, this study examines workgroup processes and nurse outcomes as the consequences of nurse turnover and the mediating effect of workgroup processes on the nurse turnover–nurse outcomes relationship.MethodsA cross-sectional design was adopted to investigate the data collected from 264 staff nurses. Furthermore, six-month turnover rates, workgroup processes (nurse–nurse collaboration, team cohesion), and nurse outcomes (job satisfaction, intent to leave) were utilized in the multivariate regression models.ResultsOverall, 53 (24.4%) nurses had worked in nursing units with a zero six-month turnover rate. The average mean six-month turnover rate was 15.5%. Nurse turnover adversely affected nurses’ job satisfaction and several subscales of team cohesion including task cohesion and social cohesion. Team cohesion partially mediated the relationship between nurse turnover and job satisfaction.ConclusionNurse turnover decreased job satisfaction and team cohesion, and team cohesion partially mediated the nurse turnover–nurse outcomes relationship. These findings provide evidence supporting the significant adverse effects of nurse turnover and suggest the potential role of workgroup processes in explaining the underlying mechanism of the relationship between nurse turnover and nurse outcomes.Implications for nursing and health policyHealthcare organizations must create a positive work environment to reduce nurse turnover. Further, states and countries should try to develop and establish nursing and health policies to prevent turnover.
Determinants and indicators of successful aging as a multidimensional outcome: a systematic review of longitudinal studies
Authors: Rodrigues Caue Egea , Grandt Caine Lucas , Alwafa Reem Abu , Badrasawi Manal , Aleksandrova Krasimira 
Published: November 2023

BackgroundSuccessful aging (SA) has been coined as a term to describe the multidimensional aspects associated with achieving optimal combination of physical and mental health along with social well-being health, mental and social well-being at older age. In recent years there has been an increased interest in understanding the role of determinants of SA, such as demographic, biological, behavioral, psychological and social factors. To synthesize the recent evidence, we conducted a systematic review of longitudinal studies on a range of determinants and indicators of SA defined as a multidimensional outcome.MethodsA systematic search of PubMed, MEDLINE and Web of Science for finding eligible papers published between August 2016 and June 2023 was conducted following the Preferred Reporting Items for a Systematic Review and Meta-Analysis (PRISMA) guidelines. The review protocol was registered in PROSPERO International Prospective Register of Systematic Reviews (Registration number: CRD42021250200). The web-based automated screening tool–Rayyan–was used for title and abstract screening. The study quality was assessed using the Quality in Prognosis Studies (QUIPS) tool.ResultsA total of 3,191 records were initially identified using the predefined search strategy. Out of 289 articles selected for full text screening, 22 were found eligible and included in the review. A variety of factors have been explored in relation to SA, ranging from socio-demographic factors, nutrition, lifestyle, biological pathways, psychological health, and well-being. Overall, the results of recent studies have confirmed the role of metabolic health, adherence to healthy dietary patterns, such as the Mediterranean diet, physical activity, non-smoking, and higher socio-economic status as main factors associated with higher odds for SA. Emerging research highlights the role of psycho-social factors and early life health as determinants of SA.ConclusionIn summary, this review highlights the importance of healthy living and monitoring metabolic risk along with sustaining psychological well-being in adult life as major determinants of SA. Further methodological and research work on SA would pave the way toward development of adequate health promotion policies in aging societies.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021250200, CRD42021250200.
Is the COVID-19 epidemic affecting the body mass of Chinese teenagers? – A longitudinal follow-up study
Authors: Qin Guoyang , Li Hui , Qin Yong , Liu Bin 
Published: November 2023

BackgroundAfter the spread and outbreak of COVID-19 worldwide, the learning, lifestyle, and health level of young individuals have been immensely impacted. With regard to the existing studies, the development trend of adolescents’ body shape in the late COVID-19 period is not sufficiently analyzed, and relevant targeted investigation is lacking. This study aimed to explore the body mass index (BMI) changes of 6–14 years-old adolescents before and after the COVID-19 epidemic, and to provide a reference for promoting the continuous enhancement of adolescent health.MethodsThe BMI and related data pertaining to 93,046 individuals from 2019 to 2022 were collected by cluster sampling, and changes in the BMI Z score and detection rate of overweight and obese adolescents before and after the epidemic were analyzed. Furthermore, the trend of obesity rates among adolescents in Jinan from 2019 to 2022 was analyzed using a logistic regression analysis model.ResultsThe one-way ANOVA models indicated that the BMI Z score of 6–14 years-old adolescents in 2020 significantly increased compared to 2019 (p &lt; 0.01), and decreased in 2021 and 2022; in 2020, the obesity rate of adolescents exhibited a significant increase; however, the rate decreased after being controlled in 2021 and 2022. The normal-body size proportion continued to rise (p &lt; 0.01), and adolescents of different age groups and genders exhibited similar development trends; the results of the logistic regression analysis indicate that there was a significant increase in obesity rates in 2020, adolescents of different age groups and genders exhibited similar development trends (p &lt; 0.05).ConclusionThis study demonstrated that the COVID-19 epidemic impacts the BMI and obesity detection rate of adolescents. Adolescents from different age groups and genders exhibited similar development trends.
Sexually transmitted diseases knowledge assessment and associated factors among university students in the United Arab Emirates: a cross-sectional study
Authors: Alshemeili Abdulla , Alhammadi Ahmed , Alhammadi Abdulrahman , Al Ali Mohamed , Alameeri Eisa Saud , Abdullahi Aminu S. , Abu-Hamada Bayan , Sheek-Hussein Mohamud M. , Al-Rifai Rami H. , Elbarazi Iffat 
Published: November 2023

BackgroundSexually transmitted diseases and infections (STDIs) remain a serious public health menace with over 350 million cases each year. Poor knowledge of STDIs has been identified as one of the bottlenecks in their control and prevention. Hence, assessment of knowledge, both general and domain-specific, is key to the prevention and control of these diseases. This study assessed the knowledge of STDIs and identified factors associated with STDI knowledge among university students in the United Arab Emirates (UAE).MethodsThis is a cross-sectional study among 778 UAE University students across all colleges. An online data collection tool was used to collect data regarding the participants' demographics and their level of knowledge of STDIs across different domains including general STDI pathogens knowledge (8 items), signs and symptoms (9 items), mode of transmission (5 items), and prevention (5 items). Knowledge was presented both as absolute and percentage scores. Differences in STDI knowledge were statistically assessed using Mann-Whitney U and Chi-squared tests. Logistic regression models were further used to identify factors associated with STDI knowledge.ResultsA total of 778 students participated in the study with a median age of 21 years (IQR = 19, 23). The overall median STDI knowledge score of the participants was 7 (out of 27), with some differences within STDI domains–signs &amp; symptoms (1 out of 9), modes of transmission (2 out of 5), general STDI pathogens (2 out of 8), and prevention (1 out of 5). Higher STDI knowledge was significantly associated with being non-Emirati (OR = 1.85, 95% CI = 1.24–2.75), being married (OR = 2.89, 95% CI = 1.50–5.56), residing in emirates other than Abu Dhabi (OR = 1.61, 95% CI = 1.16–2.25), and being a student of health sciences (OR = 4.45, 95% CI = 3.07–6.45).ConclusionIn general, STDI knowledge was low among the students. Having good knowledge of STDIs is essential for their prevention and control. Therefore, there is a need for informed interventions to address the knowledge gap among students, youths, and the general population at large.
Association between acoustic features and brain volumes: the Framingham Heart Study
Authors: Ding Huitong , Hamel Alexander P. , Karjadi Cody , Ang Ting F. A. , Lu Sophia , Thomas Robert J. , Au Rhoda , Lin Honghuang 
Published: November 2023

IntroductionAlthough brain magnetic resonance imaging (MRI) is a valuable tool for investigating structural changes in the brain associated with neurodegeneration, the development of non-invasive and cost-effective alternative methods for detecting early cognitive impairment is crucial. The human voice has been increasingly used as an indicator for effectively detecting cognitive disorders, but it remains unclear whether acoustic features are associated with structural neuroimaging.MethodsThis study aims to investigate the association between acoustic features and brain volume and compare the predictive power of each for mild cognitive impairment (MCI) in a large community-based population. The study included participants from the Framingham Heart Study (FHS) who had at least one voice recording and an MRI scan. Sixty-five acoustic features were extracted with the OpenSMILE software (v2.1.3) from each voice recording. Nine MRI measures were derived according to the FHS MRI protocol. We examined the associations between acoustic features and MRI measures using linear regression models adjusted for age, sex, and education. Acoustic composite scores were generated by combining acoustic features significantly associated with MRI measures. The MCI prediction ability of acoustic composite scores and MRI measures were compared by building random forest models and calculating the mean area under the receiver operating characteristic curve (AUC) of 10-fold cross-validation.ResultsThe study included 4,293 participants (age 57 ± 13 years, 53.9% women). During 9.3 ± 3.7 years follow-up, 106 participants were diagnosed with MCI. Seven MRI measures were significantly associated with more than 20 acoustic features after adjusting for multiple testing. The acoustic composite scores can improve the AUC for MCI prediction to 0.794, compared to 0.759 achieved by MRI measures.DiscussionWe found multiple acoustic features were associated with MRI measures, suggesting the potential for using acoustic features as easily accessible digital biomarkers for the early diagnosis of MCI.
Health research systems in Somaliland: a qualitative study on perspectives of government and non-governmental staff
Authors: Ahmed Soheir H. , Kiruja Jonah , Solieman Ayanle , Wangamati Cynthia Khamala 
Published: November 2023

BackgroundGlobally, the importance of effective national health research systems has gained considerable attention. Literature indicates low research output in Africa; Africa accounts for only 2% of the world's research output and 1.3% of global publications. In Somaliland, where provision of quality healthcare services is crucial, understanding and enhancing the health research system is a critical endeavor.AimThe aim of this study is to explore the perspectives of government and non-governmental stakeholders on the health research systems in Somaliland.MethodThe study employed an exploratory qualitative study design that entailed in-depth interviews with participants. Thirty-four study participants were interviewed; they included key persons in the academic and health sector, government and international and local non-governmental organisations (NGOs) involved in health research systems. A semi structured interview guide was used to conduct the in-depth interviews with purposively selected participants. The collected data was analyzed thematically.FindingsWe found that there was no national health research center in Somaliland. The country also lacked a national health research policy. There was limited funding for research, funds were mostly from international organisations and researchers' own funds. In addition, staff working in research centers were ill equipped to conduct research and study participants highlighted the need for national health research governance.ConclusionThis study highlights the importance of health research systems in Somaliland. We recommend the establishment of a national health research institute, development of a national health research policy and priorities, allocation of sufficient and sustainable funding, capacity building of staff and strengthening of the national health research governance in health research systems.
Genetic research with Indigenous Peoples: perspectives on governance and oversight in the US
Authors: Garrison Nanibaa' A. , Carroll Stephanie Russo 
Published: November 2023

IntroductionIndigenous Peoples are increasingly exerting governance and oversight over genomic research with citizens of their nations, raising questions about how best to enforce research regulation between American Indian, Alaska Native, and Native Hawaiian peoples and researchers.MethodsUsing a community-engaged research approach, we conducted 42 semi-structured interviews with Tribal leaders, clinicians, researchers, policy makers, and Tribal research review board members about their perspectives on ethical issues related to genetics research with Indigenous Peoples in the US.ResultsWe report findings related to (1) considerations for Indigenous governance, (2) institutional relationships upholding sovereignty, (3) expectations for research approvals, and (4) agreements enacting Indigenous governance. Participants described concerns about different ways of exerting oversight, relationships and agreements between Indigenous Peoples and researchers, and gaps that need to be addressed to strengthen existing governance of genomic data.DiscussionThe results will ultimately guide policy-making and development of new strategies for Indigenous Peoples to enforce oversight in research to promote ethically and culturally appropriate research.
Enhancing skill learning with dual-user haptic feedback: insights from a task-specific approach
Authors: Zhang Yao , Wang Olyvia , Wang Yanqing , Tavakoli Mahdi , Zheng Bin 
Published: November 2023

Introduction: This study was to examine whether inter-user haptic feedback would have a differential impact on skill acquisition based on the nature of the surgical task involved. Specifically, we hypothesized that haptic feedback would facilitate target orientation more than cutting tasks in the context of laparoscopic surgery.Methods: Ten novice participants were recruited and assigned to one of two training groups. Each group underwent six half-hour training sessions dedicated to laparoscopic pattern-cutting tasks. In the haptic group, five participants received expert guidance during the training sessions, whereas the remaining five participants in the control group engaged in self-practice. All trials were recorded on video, enabling a comparative analysis of task performance between the participants’ left hand (target manipulation) and right hand (cutting task). Additionally, the number of haptic feedback instances provided to the trainees in the haptic group was recorded.Results: Practice led to a reduction in total task time, grasping time, and cutting errors. However, no significant differences were observed between the two training groups, except for the grasping time, where haptic feedback significantly reduced the grasping time compared to the control group. Moreover, the frequency of haptic feedback instances provided to the trainees was notably higher for the grasping than for the cutting task.Discussion: Our study suggests that haptic feedback has a more substantial impact on orientation tasks than on cutting tasks in laparoscopic surgery training. However, we acknowledge that a larger sample size would provide a more robust evaluation of this effect.
Challenges and opportunities from water under soft nanoconfinement
Authors: Mezzenga Raffaele 
Published: November 2023

Nanoconfined water differs significantly from bulk water and challenges our common understanding of liquid water in both its most fundamental features, as well as in many applied aspects which stem out from its peculiar behavior. This brief perspective pinpoints both challenges associated with the study of water under soft nanoconfinement as well as some opportunities which arise from it, and which would not be at reach with standard bulk water. A special focus is given to the strong nanoconfinement (∼1–10 nm) offered by inverse lipidic mesophases, viewed as a natural soft nanoconfinement environment for water.
Combined effect of age and body mass index on postoperative mortality and morbidity in laparoscopic cholecystectomy patients
Authors: Fakhoury Hana M. A. , Yousef Ziad , Tamim Hani , Daher Sarah , Attasi Abdul Aleem , Al Ajlan Abdulaziz , Hajeer Ali H. 
Published: November 2023

BackgroundPrevious studies have assessed the impact of age and body mass index (BMI) on surgery outcomes separately. This retrospective cohort study aimed to investigate the combined effect of age and BMI on postoperative mortality and morbidity in patients undergoing laparoscopic cholecystectomy.MethodsData from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database for laparoscopic cholecystectomy patients between 2008 and 2020 were analyzed. Patient demographics, functional status, admission sources, preoperative risk factors, laboratory data, perioperative variables, and 30-day postoperative outcomes were included in the dataset. Logistic regression was used to determine the association of age, BMI, and age/BMI with mortality and morbidity. Patients were stratified into different subcategories based on their age and BMI, and the age/BMI score was calculated. The chi-square test, independent sample t-test, and ANOVA were used as appropriate for each category.ResultsThe study included 435,052 laparoscopic cholecystectomy patients. Logistic regression analysis revealed that a higher age/BMI score was associated with an increased risk of mortality (adj OR 13.13 95% CI, 9.19–18.77, p &lt; 0.0001) and composite morbidity (adj OR 2.57, 95% CI 2.23–2.95, p &lt; 0.0001).ConclusionOlder age, especially accompanied by a low BMI, appears to increase the post-operative mortality and morbidity risks in laparoscopic cholecystectomy patients, while paradoxically, a higher BMI seems to be protective. Our hypothesis is that a lower BMI, perhaps secondary to malnutrition, can carry a greater risk of surgery complications for the elderly. Age/BMI is strongly and positively associated with mortality and morbidity and could be used as a new scoring system for predicting outcomes in patients undergoing surgery. Nevertheless, laparoscopic cholecystectomy remains a very safe procedure with relatively low complication rates.
Feasibility and safety of one-stage sacral laminoplasty with autologous sacral laminar reimplantation fixed by absorbable fixation clamps in direct microsurgical treatment of symptomatic sacral extradural spinal meningeal cysts
Authors: Yin Xiaoliang , Zhang Jia , Ma Qianquan , Chen Suhua , Wu Chao , Yang Chenlong , Si Yu , Jiang Haihui , Guo Wei , Liu Ying , Yuan Huishu , Yang Jun , Sun Jianjun 
Published: November 2023

IntroductionSacral laminoplasty with titanium mesh and titanium screws can reduce symptomatic sacral extradural spinal meningeal cysts (SESMCs) recurrence and operation complications. However, due to a defect or thinning of the sacrum, the screws cannot be securely anchored and there are also problems with permanent metal implantation for titanium mesh and screws. We propose that sacral laminoplasty with absorbable clamps can provide rigid fixation even for a thinned or defected sacrum without leaving permanent metal implants.MethodsIn the direct microsurgical treatment of symptomatic SESMCs, we performed one-stage sacral laminoplasty with autologous sacral lamina reimplantation fixed by absorbable fixation clamps. Retrospectively, we analyzed intraoperative handling, planarity of the sacral lamina, and stability of the fixation based on clinical and radiological data.ResultsBetween November 2021 to October 2022, we performed sacral laminoplasty with the absorbable craniofix system in 28 consecutive patients with SESMCs. The size of the sacral lamina flaps ranged from 756 to 1,052 mm2 (average 906.21 ± 84.04 mm2). We applied a minimum of two (in four cases) and up to four (in four cases) Craniofix clamps in the operation, with three (in 20 cases) being the most common (82.14%, 20/28) and convenient to handle. Excellent sacral canal reconstruction could be confirmed intraoperatively by the surgeons and postoperatively by CT scans. No intraoperative complications occurred.ConclusionsOne-stage sacral laminoplasty with absorbable fixation clamps is technically feasible, and applying 3 of these can achieve a stable fixation effect and are easy to operate. Restoring the normal structure of the sacral canal could reduce complications and improve surgical efficacy.