bluuebunny/crossref_metadata_2025_split huggingface dataset:
Matched-pair analysis of patients with ischemic stroke undergoing thrombectomy using next-generation balloon guide catheters
Authors: Kim Lily H , Choi John , Zhou James , Wolman Dylan , Pendharkar Arjun V , Lansberg Maarten G , Albers Gregory W , Dodd Robert , Do Huy M , Pulli Benjamin , Heit Jeremy J , Telischak Nicholas A 
Published: October 2023

BackgroundBalloon guide catheters (BGCs) have not been widely adopted, possibly due to the incompatibility of past-generation BGCs with large-bore intermediate catheters. The next-generation BGC is compatible with large-bore catheters. We compared outcomes of thrombectomy cases using BGCs versus conventional guide catheters.MethodsWe conducted a retrospective study of 110 thrombectomy cases using BGCs (n=55) and non-BGCs (n=55). Sixty consecutive thrombectomy cases in whom the BOBBY BGC was used at a single institution between February 2021 and March 2022 were identified. Of these, 55 BGC cases were 1:1 matched with non-BGC cases by proceduralists, age, gender, stent retriever + aspiration device versus aspiration-only, and site of occlusion. First-pass effect was defined as Thrombolysis In Cerebral Infarction 2b or higher with a single pass.ResultsThe BGC and non-BGC cohorts had similar mean age (67.2 vs 68.9 years), gender distribution (43.6% vs 47.3% women), median initial National Institutes of Health Stroke Scale score (14 vs 15), and median pretreatment ischemic core volumes (12 mL vs 11.5 mL). BGC and non-BGC cases had similar rates of single pass (60.0% vs 54.6%), first-pass effect (58.2% vs 49.1%), and complications (1.8% vs 9.1%). In aspiration-only cases, the BGC cohort had a significantly higher rate of first-pass effect (100% vs 50.0%, p=0.01). BGC was associated with a higher likelihood of achieving a modified Rankin Scale score of 2 at discharge (OR 7.76, p=0.02). No additional procedural time was required for BGC cases (46.7 vs 48.2 min).ConclusionBGCs may be safely adopted with comparable procedural efficacy, benefits to aspiration-only techniques, and earlier functional improvement compared with conventional guide catheters.
Impact of gender, ethnicity and social deprivation on access to surgical or transcatheter aortic valve replacement in aortic stenosis: a retrospective database study in England
Authors: Rice Caoimhe T , Barnett Sophie , O'Connell Shea P , Akowuah Enoch , Appleby Clare E , Chambers John B , Shah Benoy N , Blackman Daniel J 
Published: October 2023

ObjectiveTo assess gender, ethnicity, and deprivation-based differences in provision of aortic valve replacement (AVR) in England for adults with aortic stenosis (AS).MethodsWe retrospectively identified adults with AS from the English Hospital Episode Statistics (HES) between April 2016 and March 2019 and those who subsequently had an AVR. We separately used HES-linked Clinical Practice Research Datalink (CPRD) to identify people with AVR and evaluate the timeliness of their procedure (CPRD-AVR cohort). ORs for AVR in people with an AS diagnosis were estimated using multivariable logistic regression adjusted for age, region and comorbidity. AVR was considered timely if performed electively and without evidence of cardiac decompensation before AVR.Results183 591 adults with AS were identified in HES; of these, 31 436 underwent AVR. The CPRD-AVR cohort comprised 10 069 adults. Women had lower odds of receiving AVR compared with men (OR 0.65; 95% CI 0.63 to 0.66); as did people of black (OR 0.70; 95% CI 0.60 to 0.82) or South Asian (OR 0.75; 95% CI 0.69 to 0.82) compared with people of white ethnicities. People in the most deprived areas were less likely to receive AVR than the least deprived areas (OR 0.8; 95% CI 0.75 to 0.86). Timely AVR occurred in 65% of those of white ethnicities compared with 55% of both those of black and South Asian ethnicities. 77% of the least deprived had a timely procedure compared with 58% of the most deprived; there was no gender difference.ConclusionsIn this large, national dataset, female gender, black or South Asian ethnicities and high deprivation were associated with significantly reduced odds of receiving AVR in England. A lower proportion of people of minority ethnicities or high deprivation had a timely procedure. Public health initiatives may be required to increase clinician and public awareness of unconscious biases towards minority and vulnerable populations to ensure timely AVR for everyone.
Src inhibition rescues FUNDC1-mediated neuronal mitophagy in ischaemic stroke
Authors: Tang Tianchi , Hu Li-bin , Ding Chao , Zhang Zhihua , Wang Ning , Wang Tingting , Zhou Hang , Xia Siqi , Fan Linfeng , Fu Xiong-jie , Yan Feng , Zhang Xiangnan , Chen Gao , Li Jianru 
Published: October 2023

BackgroundIschaemic stroke triggers neuronal mitophagy, while the involvement of mitophagy receptors in ischaemia/reperfusion (I/R) injury-induced neuronal mitophagy remain not fully elucidated. Here, we aimed to investigate the involvement of mitophagy receptor FUN14 domain-containing 1 (FUNDC1) and its modulation in neuronal mitophagy induced by I/R injury.MethodsWild-type and FUNDC1 knockout mice were generated to establish models of neuronal I/R injury, including transient middle cerebral artery occlusion (tMCAO) in vivo and oxygen glucose deprivation/reperfusion in vitro. Stroke outcomes of mice with two genotypes were assessed. Neuronal mitophagy was analysed both in vivo and in vitro. Activities of FUNDC1 and its regulator Src were evaluated. The impact of Src on FUNDC1-mediated mitophagy was assessed through administration of Src antagonist PP1.ResultsTo our surprise, FUNDC1 knockout mice subjected to tMCAO showed stroke outcomes comparable to those of their wild-type littermates. Although neuronal mitophagy could be activated by I/R injury, FUNDC1 deletion did not disrupt neuronal mitophagy. Transient activation of FUNDC1, represented by dephosphorylation of Tyr18, was detected in the early stages (within 3 hours) of neuronal I/R injury; however, phosphorylated Tyr18 reappeared and even surpassed baseline levels in later stages (after 6 hours), accompanied by a decrease in FUNDC1-light chain 3 interactions. Spontaneous inactivation of FUNDC1 was associated with Src activation, represented by phosphorylation of Tyr416, which changed in parallel with the level of phosphorylated FUNDC1 (Tyr18) during neuronal I/R injury. Finally, FUNDC1-mediated mitophagy in neurons under I/R conditions can be rescued by pharmacological inhibition of Src.ConclusionsFUNDC1 is inactivated by Src during the later stage (after 6 hours) of neuronal I/R injury, and rescue of FUNDC1-mediated mitophagy may serve as a potential therapeutic strategy for treating ischaemic stroke.
$$\theta $$-diagram technique for $${\mathcal {N}}=1$$, $$d=4$$ superfields
Authors: Bason D. , Billò M. 
Published: October 2023

AbstractWe describe a diagrammatic procedure to carry out the Grassmann integration in super-Feynman diagrams of 4d theories expressed in terms of $${\mathcal {N}}=1$$

N
=
1

superfields. This method is alternative to the well known D-algebra approach. We develop it in detail for theories containing vector, chiral and anti-chiral superfields, with the type of interactions which occur in $${\mathcal {N}}=2$$

N
=
2

SYM theories with massless matter, but it would be possible to extend it to other cases. The main advantage is that this method is algorithmic; we implemented it as a Mathematica program that, given the description of a super Feynman diagram in momentum space, returns directly the polynomial in the momenta produced by the Grassmann integration.
Probing gluon GTMDs through exclusive coherent diffractive processes
Authors: Boer Daniël , Setyadi Chalis 
Published: October 2023

AbstractWe extend a previous GTMD model to improve the description of the HERA data on diffractive dijet production, and include exclusive coherent diffractive $$J/\psi $$

J
/
ψ

production data. We find that within our gluon GTMD model context and assumptions, there is considerable tension between the data for these two types of processes concerning the t dependence. Photo- and electroproduction data for protons and nuclei from EIC and UPC data from LHC and RHIC can help to establish whether a common GTMD description is possible, as one would expect, and to facilitate studies of such data we provide predictions for the various experiments. We point out explicitly in which sense this goes beyond the description in terms of GPDs.
A braneworld model in a massive gravity
Authors: Yang Ke , Guo Shi-Fa , Gu Bao-Min 
Published: October 2023

AbstractA Randall–Sundrum-like braneworld scenario is constructed in a 5D extension of the Lorentz-violating massive gravity. The gauge hierarchy problem is solved in current model. The linear perturbations are calculated, and it is found that the tensor and vector perturbations are robust and free from the ghost and tachyonic instabilities, however, the scalar perturbation is a ghost filed. After Kaluza–Klein reduction, all the tensor, vector and scalar modes are massive and possess the mass splitting of order of TeV in their respective mass spectra. The massive ground states of tensor and scalar modes propagate only along the brane, however, the vector ground state is absent in the mass spectrum. By introducing the Goldberger-Wise mechanism to stabilize the extra dimension, the 4D effective theory on the brane includes a nearly massless graviton plus three towers of very massive spin-2, spin-1 and ghost spin-0 particles.
A fractional matter sector for general relativity
Authors: Palacios J. , Teodoro A. Di , Fuenmayor E. , Contreras E. 
Published: October 2023

AbstractIn this work, we construct a fractional matter sector for general relativity. In particular, we propose a suitable fractional anisotropy function relating both the tangential and radial pressure of a spherically symmetric fluid based on the Grünwald–Letnikov fractional derivative. The system is closed by implementing the polytropic equation of state for the radial pressure. We solve the system of integro-differential equations by Euler’s method and explore the behavior of the physical quantities, namely, the normalized density energy, the normalized mass function, and the compactness.
How does Twitter account moderation work? Dynamics of account creation and suspension on Twitter during major geopolitical events
Authors: Pierri Francesco , Luceri Luca , Chen Emily , Ferrara Emilio 
Published: October 2023

AbstractSocial media moderation policies are often at the center of public debate, and their implementation and enactment are sometimes surrounded by a veil of mystery. Unsurprisingly, due to limited platform transparency and data access, relatively little research has been devoted to characterizing moderation dynamics, especially in the context of controversial events and the platform activity associated with them. Here, we study the dynamics of account creation and suspension on Twitter during two global political events: Russia’s invasion of Ukraine and the 2022 French Presidential election. Leveraging a large-scale dataset of 270M tweets shared by 16M users in multiple languages over several months, we identify peaks of suspicious account creation and suspension, and we characterize behaviors that more frequently lead to account suspension. We show how large numbers of accounts get suspended within days of their creation. Suspended accounts tend to mostly interact with legitimate users, as opposed to other suspicious accounts, making unwarranted and excessive use of reply and mention features, and sharing large amounts of spam and harmful content. While we are only able to speculate about the specific causes leading to a given account suspension, our findings contribute to shedding light on patterns of platform abuse and subsequent moderation during major events.
Towards Intersectional Moderation: An Alternative Model of Moderation Built on Care and Power
Authors: Gilbert Sarah 
Published: October 2023

Shortcomings of current models of moderation have driven policy makers, scholars, and technologists to speculate about alternative models of content moderation. While alternative models provide hope for the future of online spaces, they can fail without proper scaffolding. Community moderators are routinely confronted with similar issues and have therefore found creative ways to navigate these challenges. Learning more about the decisions these moderators make, the challenges they face, and where they are successful can provide valuable insight into how to ensure alternative moderation models are successful.
In this study, I perform a collaborative ethnography with moderators of r/AskHistorians, a community that uses an alternative moderation model, highlighting the importance of accounting for power in moderation. Drawing from Black feminist theory, I call this "intersectional moderation." I focus on three controversies emblematic of r/AskHistorians' alternative model of moderation: a disagreement over a moderation decision; a collaboration to fight racism on Reddit; and a period of intense turmoil and its impact on policy. Through this evidence I show how volunteer moderators navigated multiple layers of power through care work. To ensure the successful implementation of intersectional moderation, I argue that designers should support decision-making processes and policy makers should account for the impact of the sociotechnical systems in which moderators work.
Reconsidering Priorities for Digital Maternal and Child Health: Community-centered Perspectives from South Africa
Authors: Coleman Toshka , Till Sarina , Farao Jaydon , Shandu Londiwe , Khuzwayo Nonkululeko , Muthelo Livhuwani , Mbombi Masenyani , Bopape Mamare , van Heerden Alastair , Mothiba Tebogo , Norris Shane , Verdezoto Nervo , Densmore Melissa 
Published: October 2023

Especially in developing regions, parents are rarely given a direct voice in the design of digital maternal and child health (MCH) interventions. Instead, MCH needs and requirements are driven by organizations and health workers. In this research, we engage with both rural and urban parents and community leaders to better understand their challenges and priorities for digital MCH and propose a parent-centered agenda for human-computer interaction research. This paper reports on the community-based, digital MCH priorities identified in our research, and describes how we approached community discourse and co-design of digital initiatives for these priorities, through parent-centered workshops with low-resource South African communities. Furthermore, we provide the parent-centered design opportunities and tensions we discovered for digital MCH in South African contexts, such as designing for local contexts and languages, designing for accessibility and connectedness, and highlighting the underdeveloped digital MCH niches. Finally, we highlight the importance of including facilitators for co-design workshops, such as using intermediaries and design cards.
Investigating Security Folklore: A Case Study on the Tor over VPN Phenomenon
Authors: Fassl Matthias , Ponticello Alexander , Dabrowski Adrian , Krombholz Katharina 
Published: October 2023

Users face security folklore in their daily lives in the form of security advice, myths, and word-of-mouth stories. Using a VPN to access the Tor network, i.e., Tor over VPN, is an interesting example of security folklore because of its inconclusive security benefits and its occurrence in pop-culture media.
Following the Theory of Reasoned Action, we investigated the phenomenon with three studies: (1) we quantified the behavior on real-world Tor traffic and measured a prevalence of 6.23%; (2) we surveyed users' intentions and beliefs, discovering that they try to protect themselves from the Tor network or increase their general security; and (3) we analyzed online information sources, suggesting that perceived norms and ease-of-use play a significant role while behavioral beliefs about the purpose and effect are less crucial in spreading security folklore. We discuss how to communicate security advice effectively and combat security misinformation and misconceptions.
Incidence of Dysmagnesemia among Medically Hospitalized Patients and Associated Clinical Characteristics: A Prospective Cohort Study
Authors: Al Shukri Zahra , Al-Maqbali Juhaina Salim , Al Alawi Abdullah M. , Al Riyami Nafila , Al Riyami Sulaiman , Al Alawi Hiba , Al Farai Qatiba , Falhammar Henrik 
Published: October 2023

Background. Magnesium (Mg) disorders are common among hospitalized patients and are linked to poor health outcomes. We aimed to determine the incidence of dysmagnesemia among medically hospitalized patients and to identify factors that are associated with dysmagnesemia. Methods. A prospective cohort study was conducted at Sultan Qaboos University Hospital (SQUH) from April 1st, 2022, to October 31st, 2022, and involved hospitalized adult patients (≥18 years) under the care of the general internal medicine unit. The patients’ serum total magnesium (Mg) concentrations were categorized as hypomagnesemia (≤0.69 mmol/L), hypermagnesemia (≥1.01 mmol/L), or dysmagnesemia, which encompassed either hypomagnesemia or hypermagnesemia. Results. Of the 304 patients evaluated, dysmagnesemia was observed in 22.0%, which comprised of 17.4% with hypomagnesemia and 4.6% with hypermagnesemia. Statistically significant associations were identified between hypermagnesemia and chronic kidney disease (CKD) (

p

= 0.05) and elevated creatinine levels (

p

< 0.01) and lower estimated glomerular filtration rate (eGFR) (

p

< 0.01). Hypomagnesemia was linked to lower ionized calcium (

p

= 0.03) and admission due to infectious diseases (

p

= 0.02). However, ordered regression analysis did not find any significant associations with the different magnesium groups. Conclusion. Dysmagnesemia was prevalent among hospitalized patients and was associated with different factors; however, ordered regression analysis did not find any association with the different magnesium group, probably due to the limited number of included individuals.
Shépa
Authors: Tso Bendi , Gyatso Marnyi , Tsering Naljor , Turin Mark , Members of the Choné Tibetan Community  
Published: October 2023

Shépa: ‘explanation’ or ‘elucidation’ in Tibetan.
A form of oral poetry sung antiphonally in a question-and-answer style.
This book contains a unique collection of Tibetan oral narrations and songs known as Shépa, as these have been performed, recorded and shared between generations of Choné Tibetans from Amdo living in the eastern Tibetan Plateau. Presented in trilingual format — in Tibetan, Chinese and English — the book reflects a sustained collaboration with and between members of the local community, including narrators, monks, and scholars, calling attention to the diversity inherent in all oral traditions, and the mutability of Shépa in particular.
From creation myths to Bon and Buddhist cosmologies and even wedding songs, Shépa engages with and draws on elements of religious traditions, historical legacies and deep-seated cultural memories within Choné and Tibet, revealing the multi-layered conceptualization of the Tibetan physical world and the resilience of Tibetan communities within it. This vital and unique collection, part of the World Oral Literature Series, situates Shépa in its ethnographic context, offering insights into the preservation and revitalization of intangible cultural heritage in the context of cultural Tibet, Indigenous studies and beyond.
Scholars and students in the fields of anthropology, linguistics, ethnic and minority relations, critical Indigenous studies, Tibetan studies, Himalayan studies, Asian studies and the broader study of China will find much to reward them in this book, as will all readers interested in the documentation and preservation of endangered oral traditions, intangible cultural heritage, performance and textuality, and Tibetan literature and religions.
Diversity of Lagged Relationships in Global Means of Surface Temperatures and Radiative Budgets for CMIP6 piControl Simulations
Authors: Tsuchida Ko , Mochizuki Takashi , Kawamura Ryuichi , Kawano Tetsuya , Kamae Youichi 
Published: October 2023

Abstract
Radiative feedbacks over interannual time scales can be potentially useful for global warming estimation. However, the diversity of the lead–lag relationships in global mean surface temperature (GMST) and net radiation flux at the top of the atmosphere (GMTOA) create uncertainty during the estimation of radiative feedbacks. In this study, key physical processes controlling lead–lag relationships were elucidated by categorizing preindustrial control simulations of CMIP6 into three groups based on cross correlation values of GMTOA against GMST at lag 0 and lag +1 year. The diversity in the lead–lag relationships was primarily caused by the climatological state difference of the atmosphere over the equatorial Pacific, which modulated the strength of convective activity and sensitivity of low-level clouds. Diminished atmospheric stability caused enhanced convective activity, more efficient energy release, and smaller lags. In addition, enhanced stability in the lower atmosphere rendered the low-level clouds more sensitive to sea surface temperature changes and considerably delayed the radiative response. The climatological state difference of the atmosphere resulted from model-inherent atmospheric conditions. These findings suggest that the diversity of lead–lag relationships of GMST and GMTOA over interannual time scales could represent the characteristics of general atmospheric circulation models and possible solutions of the actual atmosphere, which could also affect long-term feedback features.
Key Findings on Computed Tomography of the Head that Predict Death or the Need for Neurosurgical Intervention From Traumatic Brain Injury
Authors: Noorbakhsh Soroosh , Keirsey Michael , Hess Alexis , Bellu Kyle , Laxton Steven , Byerly Saskya , Filiberto Dina M. , Kerwin Andrew J. , Stein Deborah M. , Howley Isaac W. 
Published: October 2023

Background Traumatic brain injury (TBI) requires rapid management to avoid secondary injury or death. This study evaluated if a simple schema for quickly interpreting CT head (CTH) imaging by trauma surgeons and trainees could be validated to predict need for neurosurgical intervention (NSI) or death from TBI within 24 hours. Methods We retrospectively reviewed TBI patients presenting to our trauma center in 2020 with blunt mechanism and GCS ≤ 12. Primary independent variables were presence of 7 normal findings on CTH (CSF at foramen magnum, open fourth ventricle, CSF around quadrigeminal plate, CSF around cerebral peduncles, absence of midline shift, visible sulci/gyri, and gray-white differentiation). Trauma surgeons and trainees separately evaluated each patient’s CTH, scoring findings as normal or abnormal. Primary outcome was NSI/death in 24 hours. Results Our population consisted of 444 patients; 21.4% received NSI or died within 24 hours. By trainees’ interpretation, 5.8% of patients without abnormal findings had NSI/death vs 52.0% of patients with ≥1 abnormality; attending interpretation was 8.7% and 54.9%, respectively ( P < .001). Sulci/gyri effacement, midline shift, and cerebral peduncle effacement maximized sensitivity and specificity for predicting NSI/death. Considering pooled results, when ≥1 of those 3 findings was abnormal, sensitivity was 77.89%, specificity was 80.80%, positive predictive value was 52.48%, and negative predictive value was 93.07%. Discussion Any single abnormality in this schema significantly predicted a large increase in NSI/death in 24 hours in TBI patients, and three particular findings were most predictive. This schema may help predict need for intervention and expedite management of moderate/severe TBI.