bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risky sexual behavior and associated factors among in-school adolescents: a school-based, cross-sectional study
Authors: Habeeb Omoponle Adewuyi , Veronica Dwarika 
Published: October 2023

Despite increased sexual education, secondary school students in Nigeria are still engaging in risky sexual behavior. This may be due to various social, psychological, and physical factors. The study looked at how family structure, peer pressure, and self-esteem affected the likelihood that adolescents in Ibadan, Oyo State, Nigeria, would engage in risky sexual behavior. For this study, a descriptive research design using correlational data was adopted. The study adopted the purposive sampling method in selecting 200 in-school adolescents. Valid and standardized instruments including risky sexual behavior rating scale (α=0.758), peer pressure scale (α=0.714), self-esteem scale (α=0.826) and family structure scale (α=0.827) were used for information gathering. Three research questions were raised and answered.
Data collected was analyzed using simple percentages, Pearson product-moment correlation, and multiple regression statistical method at the 0.05 level of significance. Findings revealed that risky sexual behavior of secondary school students is significantly correlated with peer pressure (r=.594; p<.05), self-esteem (r=.605; p<.05), and family structure (r=.521; p<.05). The value of R=.783 and adjusted R2=.613 were observed. The analysis of variance, performed on the multiple regressions, yielded an F-ratio value of 98.056. In terms of the magnitude of contribution, self-esteem made the most significant contribution (β=.509; t=8.647; p<0.05) to the prediction, followed by peer pressure (β=.342; t=3.545; p<0.05) and family structure (β=.223; t=1.348; p<0.05).
Based on these findings, it was concluded, that peer pressure, self-esteem, and family structure influence risky sexual behavior of adolescents. It is therefore recommended, that students’ sense of self is very important and should be improved and also that students should be guided, particularly in meeting different categories of people in the school setting, such as peers, teachers, and others with varying degrees of sexual attitudes because it affects the students’ sexual behaviors.
Tensor network variational optimizations for real-time dynamics: Application to the time-evolution of spin liquids
Authors: Ponnaganti Ravi Teja , Mambrini Matthieu , Poilblanc Didier 
Published: October 2023

Within the Projected Entangled Pair State (PEPS) tensor network formalism, a simple update (SU) method has been used to investigate the time evolution of a two-dimensional U(1) critical spin-1/2 spin liquid under Hamiltonian quench [Phys. Rev. B 106, 195132 (2022)]. Here we introduce two different variational frameworks to describe the time dynamics of SU(2)-symmetric translationally-invariant PEPS, aiming to improve the accuracy. In one approach, after using a Trotter-Suzuki decomposition of the time evolution operator in term of two-site elementary gates, one considers a single bond embedded in an environment approximated by a Corner Transfer Matrix Renormalization Group (CTMRG). A variational update of the two tensors on the bond is performed under the application of the elementary gate and then, after symmetrization of the site tensors, the environment is updated. In the second approach, a cluster optimization is performed on a finite (periodic) cluster, maximizing the overlap of the exact time-evolved state with a symmetric finite-size PEPS ansatz. Observables are then computed on the infinite lattice contracting the infinite-PEPS (iPEPS) by CTMRG. We show that the variational schemes outperform the SU method and remain accurate over a significant time interval before hitting the entanglement barrier. Studying the spectrum of the transfer matrix, we find that the asymptotic correlations are very well preserved under time evolution, including the critical nature of the singlet correlations, as expected from the Lieb-Robinson (LR) bound theorem. Consistently, the system (asymptotic) boundary is found to be described by the same Conformal Field Theory of central charge c = 1c=1 during time evolution. We also compute the time-evolution of the short distance spin-spin correlations and estimate the LR velocity.
Water footprint approach in measuring the potential of bioenergy production from agricultural products
Authors: Zeng Fangfang 
Published: October 2023

Abstract
Promoting the supply of energy from biomass to reduce the emission of greenhouse gases has resulted in focusing on the production of important products from the perspective of energy and, ultimately, increasing water consumption. Therefore, in the present study, an index called water footprint was used to investigate the link between water and bioenergy. For this purpose, information related to grain maize crops was collected in the study plains of Fujian Province in eastern China. Based on the calculations, it was found that the water footprint of maize products in the province was equal to 3,728 m3/ton on average, and the water footprint of its biomass was estimated to be 219.6 m3/ton. Moreover, the investigation of the water footprint of maize biomass energy showed that the highest and lowest water footprints per unit of energy are found in Ningde and Zhangzhou, respectively. It was also found that the plains of Zhangzhou, Ningde and Xiamen have little priority for biomass production because the water footprint of their biomass energy is less than 900 MJ/m3. On the other hand, Nanping and Putian plains with bioenergy water footprints between 1,500 and 1,800 MJ/m3 have high priority for using maize biomass for energy production.
Review on descaling and anti-scaling technology of heat exchanger in high-salt wastewater thermal desalination
Authors: Wu Zhigen , Yan Zihan , Zhang Qinghong , Zhu Yuting , Luo Maohui , Zhou Dan 
Published: October 2023

Abstract

Thermal desalination evaporation of high-salt wastewater has been widely used in industry because of the proposed concept of ‘zero liquid discharge’. However, due to the high content of Ca2+ and Mg2+ in high-salt wastewater, the heat exchanger, as the main treatment equipment, suffers from serious scaling problems. This review presents descaling and scale inhibition technologies of high-salt wastewater. The advantages and disadvantages of various technologies are summarized and analyzed to provide theoretical support for the research of descaling and anti-scaling of heat exchangers with high-salt wastewater. In future industrial development, the synergistic application of electromagnetic water treatment technology and scale inhibitors can significantly improve the anti-scaling effect, which can reach over 95% stably. Furthermore, the addition of a physical field can also expand the application range of scale inhibitors.
A Combination of EGFR Inhibitors and AE-PDT Could Synergistically Suppress
Breast Cancer Progression
Authors: Niu Yajuan , Guo Xiya , Han Wang , Han Xiaoyu , Li Kaiting , Tian Si , Zhu Ying , Bai DingQun , Chen Qing 
Published: October 2023

Background:
Breast cancer is the most frequently diagnosed malignancy and the leading cause of cancerrelated
deaths in women. Activation of EGFR by EC-secreted EGFR ligands promotes breast cancer progression. Current
treatments provide limited benefits in triple-negative breast cancer (TNBC). Photodynamic therapy (PDT) has
been proven effective for the treatment of TNBC through the EGFR pathway, but the underlying mechanism is still
unclear.

Purpose:
The purpose of this study was to determine the role of the EGFR pathway in the treatment of PDT on TNBC
in a co-culture system.

Methods:
MB-231 and HUVEC were co-cultured for experiments (HU-231). Cell viability and ROS production were
detected after AE-PDT, a combination of EGFR inhibitors (AEE788)with PDT to test angiogenesis, apoptosis, and
pyroptosis. WB detects expression of EGFR. EGFR, P-EGFR, VEGF, caspase-1, capase-3, and GSDMD .

Results:
AE-PDT inhibited HU-231 cell proliferation and tumor angiogenesis, and induced cell apoptosis and pyroptosis
by promoting ROS production. AEE788, an inhibitor of the EGFR, enhanced HU-231 cell killing after AE-PDT

Conclusion:
Our study suggested that the combination of EGFR inhibitors and AE-PDT could synergistically suppress
breast cancer progression, providing a new treatment strategy.
L-proline as co-crystal forming amino acid for enhanced dissolution rate of lamotrigine: Development of buccal tablet
Authors: Abdelrahman Howaida , Essa Ebtesam , El Maghraby Gamal , Arafa Mona 
Published: October 2023

Lamotrigine is an antiepileptic drug with slow dissolution rate which can reduce its oral bioavailability. In addition, it was reported to have first pass metabolism. Accordingly, the aim of this work was to enhance its dissolution rate utilizing co-crystallization technique to be suitable for incorporation in buccal dosage form. L-proline was selected as co-crystal co-former for enhancing dissolution in addition to its beneficial anticonvulsant properties. Formulations containing lamotrigine and L-proline at different molar ratios were prepared using ethanol assisted co-grinding. The prepared formulations were characterized using FTIR, X-Ray powder diffraction, differential scanning calorimetry and dissolution studies. The formulation recorded the highest dissolution rate was incorporated in fast disintegrating tablet for buccal use. Characterization techniques suggested the formation of lamotrigine-l-proline co-crystals with 1:2 molar ratio being optimum for interaction. This interaction resulted in significant enhancement in dissolution rate with the ratio of lamotrigine to proline at molar ratio of 1:4 showed greatest dissolution rate (% DE= 80.57). The prepared tablet utilizing lamotrigine and L-proline at molar ratio of 1:4 showed fast disintegration and rapid dissolution rate compared with control tablet containing lamotrigine alone. The study suggested L-proline as an efficient co-crystal co-former for enhancing dissolution rate of lamotrigine for buccal delivery.
Effectiveness of Dry Grinding and Wet Grinding Methods on Solution and Dissolution Rate of Nimodipine-HPMC Nanoparticles
Authors: Fadhila Muthia 
Published: October 2023

Nimodipine is a dihydropyridine calcium channel blocker that shares the general properties of nifedipine, but acts mainly on cerebral blood vessels. Nimodipine belongs to the Class II Biopharmaceutical Classification System (BCS) drug group, which has low solubility and high permeability. The purpose of this study was to look at the differences in the yield of nanoparticles between the dry grinding and wet grinding methods on the physicochemical properties, solubility, and dissolution rate of nimodipine nanoparticles. The nanoparticles were prepared a nimodipine: HPMC ratio of 1:0.6 using two different methods. Sample characterization was carried out using Particle Size Analyzer (PSA), Scanning Electron Microscopy (SEM), Differential Scanning Calorimetry (DSC), X-ray Diffraction (XRD), and Fourier Transform Infrared (FT-IR). The Solubility test was carried out in CO2-free distilled water and the dissolution rate was carried out in phosphate buffer pH 7.2. The solubility of pure nimodipine in CO2-free distilled water was 0.339 µg/mL, the physical mixture was 1.948 µg/mL, the dry grinding nanoparticles were 3.367 µg/mL, and the wet grinding nanoparticles were 19.952 µg/mL. The dissolution test results obtained with the percentage of pure nimodipine dissolution at 60th minutes was 33.947%, the physical mixture was 39.482%, the dry grinding nanoparticles were 49.798%, and the wet grinding nanoparticles were 56.484%. Based on the results of the study, it can be said that the nimodipine-HPMC nanoparticles significantly increased the solubility and dissolution rate of nimodipine.
Isolation and Characterization of Curcumenotone, a Sesquiterpene from Curcuma aeruginosa Roxb as Antioxidant
Authors: Suharsanti Ririn , Wahyuono Subagus , Astuti Puji , Yuniarti Nunung 
Published: October 2023

Antioxidant compounds are necessary to block the initiation of oxidation chain reactions and inhibit the formation of ROS which are the cause of various diseases. Natural antioxidants can be isolated from various sources, one of them from Curcuma aeruginosa Roxb Rhizome. This study was aimed to isolate and identify antioxidant compounds from Curcuma aeruginosa Roxb rhizome. To isolate the active compound, the 2,2-diphenyl-1-picrylhidrazyl (DPPH) free radical scavenging activity guide was used. Initially the Curcuma aeruginosa Roxb rhizome powdered material macerated with ethanol 70% to give ethanol extract (EE). The EE was then fractionated gradually with increasing polarity solvents to give n-hexane (HF), ethyl acetate (EAF), ethanol (EF) and insoluble (IF) fractions. The EF was the active fraction, was fractionated into 6 fractions (EE.a-f) based on their TLC picture. Two compounds (EF.a1 and EF.a2) were isolated from active fraction (EF.a) by preparative TLC. The EF.a2 appeared as white crystals demonstrates better activity as anti radical DPPH, having 96.24% purity (HPLC). EF.a2 appeared as a single peak in GC (Rt 12,78), and having molecular weight at m/z 234. There were 2 absorbtion peaks at 226 nm and 260 nm in Uv-Vis spectrophotometer and absorption bands at 3364, 3314, 2905 and 1653 cm-1 on the FT-IR spectrum. Based on spectroscopic data (1H-,13C-NMR) and comparison with reported data, the EF.a2 was identified as sesquiterpene, curcumenotone (C15H22O2). The curcumenotone was shown potent antioxidant in DPPH radical scavenging assay had an IC50 53.24±1.51 µg/mL, ABTS radical scavenging assay had an IC50 41.33±3.15 µg/mL, and FRAP assay had an IC50 37,82±2.02 µg/mL.
Integración de un ova para el aprendizaje significativo de la estequiometría en educación media
Authors: Urbano Mantilla Pablo César , García García Miguel Ángel , Arévalo Duarte Mayra Alejandra 
Published: October 2023

Los procesos de enseñanza de la estequiometría constituyen un verdadero desafío para los docentes, porque involucran diferentes procesos químico-matemáticos que dificultan la comprensión de los estudiantes. En este sentido, los objetos virtuales de aprendizaje [OVA] constituyen una herramienta idónea para integrar la tecnología y enriquecer los procesos de enseñanza aprendizaje. El presente estudio tiene como objetivo, implementar un objeto virtual de aprendizaje que permita la construcción de aprendizajes significativos en la enseñanza de la estequiometría en estudiantes de educación media. Se orienta desde el método cuasi-experimental con diseño de prueba pretest y postest desarrollado en tres fases: aplicación de prueba pretest, implementación del OVA, aplicación de prueba postest. Los resultados evidencian mejores resultados en la prueba postest con mayor apropiación en los conceptos de masa, volumen, molar en los procesos estequiométricos que le permiten al estudiante la asimilación teórica para interpretar situaciones, argumentar y resolver problemas. Se concluye que la enseñanza de la estequiometría a través de prácticas significativas, evidencia aumento de interés y motivación por parte de los estudiantes. Incentiva la construcción del conocimiento científico de manera crítica y objetiva en relación con los pre-saberes y la perspectiva personal. Mejora la comprensión y comunicación asertiva de los fenómenos químicos.
Surface Rupture and Fault Characteristics Associated with the 2020 Magnitude (MW) 6.6 Masbate Earthquake, Masbate Island, Philippines
Authors: Llamas Deo Carlo Escat , Marfito Bryan Jimenez , Cruz Ronald Dela , Aurelio Mario 
Published: October 2023

The magnitude (M) 6.6 earthquake that
struck Masbate Island on 18 August 2020 offers a unique opportunity to
investigate the slip and seismic behavior of the Philippine Fault in the
Masbate region. In this study, we employ InSAR, seismicity analysis, and
field investigations to comprehensively characterize the coseismic and
postseismic slip associated with the event. Our findings reveal a
50-km-long fault rupture along the Masbate segment of the Philippine
Fault, with ~23 km surface rupture mapped onshore,
despite the occurrence of interseismic creep. The slip distribution
demonstrates decreasing displacements northwestward towards the creeping
section, with a maximum left-lateral displacement of 0.97 m near the
epicenter. Toward the southeast offshore, the rupture terminates at
a fault left stepover. While the surface rupture appears relatively
straight and narrowly concentrated, the secondary ruptures and mapped
offshore faults reveal a more complex transtensional fault structure in
the vicinity of Cataingan Bay. This fault complexity represents an
asperity that facilitates high-stress accumulation and rupture
initiation. Postseismic slip persists for several months along the
onshore creeping segment. We derived a slip rate of 2.8 to 4.3 cm/year
from long-term and short-term slip measurements. Furthermore, we
calculated a recurrence interval of 16 to 41 years for earthquakes
similar to the 2020 Masbate earthquake. Our study highlights how
heterogeneity in fault properties, including geometry and coupling
state, influences the distribution of slip and magnitude of earthquakes.
The 2020 Masbate earthquake provides valuable insights into the rupture
dynamics and fault behavior of the Philippine Fault in the Masbate
region.
ANALISIS WACANA STRATEGI KOMUNIKASI PUBLIC RELATIONS PEMPROV JATENG MELALUI PROGRAM ‘JOGO TONGGO’ DI KELURAHAN BLOTONGAN KOTA SALATIGA
Authors: Afifah Sandra Lutfi , Huwae George Nicholas , Darmastuti Rini 
Published: October 2023

ABSTRACT
The Covid-19 virus pandemic that is increasingly spreading has made the Central Java Provincial Government is taking various measures to deal with Covid-19. Public Relations which has an important role in building communication with the public will be a bridge in conveying various information about Covid-19 to health protocols that must be carried out. This study aims to find out how the Public Relations communication strategy from the Central Java Provincial Government through a program ‘Jogo Tonggo’, implementation of the program, and the obstacles that occur in implementing program ‘Jogo Tonggo’ in the Blotongan village, Salatiga city. The research approach used is a qualitative approach with an discourse analysis method research. The results of this research show that the communication strategy carried out by the Public Relations of the Central Java Provincial Government and the Salatiga city government synergizes with each in disseminating of program ‘Jogo Tonggo’ to public in Blotongan village. The obstacles in implementing of program ‘Jogo Tonggo’ is the lack of capital to fulfill the social assistance in post Jogo Tonggo and the difficulty of maintaining the spirit of the ‘Jogo Tonggo’ officer unit and the public because of the pandemic that has lasted so long that it causes saturation.

Keywords: Covid-19, Public Relations, Strategy, Jogo Tonggo, Central Java.

ABSTRAK
Pandemi Covid-19 yang semakin merebak membuat Pemerintah Provinsi Jawa Tengah melakukan berbagai tindakan untuk mengatasi Covid-19. Humas yang memiliki peranan penting dalam membangun komunikasi dengan masyarakat akan menjadi jembatan dalam menyampaikan berbagai informasi mengenai Covid-19 hingga protokol kesehatan yang harus dilakukan. Penelitian ini bertujuan untuk mengetahui bagaimana strategi komunikasi Public Relations dari Pemerintah Provinsi Jawa Tengah melalui sebuah program ‘Jogo Tonggo’, pelaksanaan program tersebut, dan hambatan-hambatan yang terjadi dalam melaksanakan program ‘Jogo Tonggo’ di Kelurahan Blotongan, Kota Salatiga. Pendekatan penelitian yang digunakan yaitu pendekatan kualitatif dengan desain penelitian metode analisis wacana. Hasil penelitian ini menunjukkan strategi komunikasi yang dilakukan Public Relations Pemerintah Provinsi Jawa Tengah dan Pemerintah Kota Salatiga saling bersinergi dalam mensosialisasikan program ‘Jogo Tonggo’ ke masyarakat Kelurahan Blotongan. Hambatan dalam pelaksanaan program ‘Jogo Tonggo’ adalah kurangnya modal untuk pemenuhan bantuan di posko Jogo Tonggo dan sulitnya menjaga semangat para satgas Jogo Tonggo dan masyarakat karena pandemi yang sudah berlangsung sangat lama sehingga menyebabkan kejenuhan.

Keywords: Covid-19, Humas, Strategi, Jogo Tonggo, Jawa Tengah.
FENOMENOLOGI OBJEKTIFIKASI SEKSUAL PADA WANITA PENGGUNA TIKTOK DAN INSTAGRAM
Authors: Marietha Andini Rizka , Najwarani Desvita , Almuttaqin Fatya Putri , Novianti Felita Eka , Sihotang Jesslyn , Wulan Roro Retno 
Published: October 2023

Abstract. Sexual objectification is someone whose body parts are separate - the eyes are used as objects for sexual use. This research uses objectification theory and symbolic interaction as grounding theory. This study uses a phenomenological approach with a qualitative descriptive method. Interviews were conducted using online media in the form of virtual meet Zoom due to limited distances and adjusting health protocols during the Covid-19 pandemic. Sexual objectivity does exist and has often happened. Publicity of sexual objectification towards women is not a natural thing because this action can harm certain parties, therefore in today's digital era it is important to be eliminated and its badness is recognized by society in order to achieve equality. Already consider social media as a means for women as media users if they have to prioritize them for media content, especially the moral values of society.
Keywords: Sexual, Objectification, Women

Abstrak. Objektifikasi seksual adalah seseorang yang bagian tubuhnya terpisah - mata digunakan sebagai objek untuk penggunaan seksual. Penelitian ini menggunakan teori objektifikasi dan interaksi simbolik sebagai landasan teori. Penelitian ini menggunakan pendekatan fenomenologis dengan metode deskriptif kualitatif. Wawancara dilakukan menggunakan media online berupa virtual meet Zoom karena keterbatasan jarak dan penyesuaian protokol kesehatan selama masa pandemi Covid-19. Objektivitas seksual memang ada dan sudah sering terjadi. Publisitas objektifikasi seksual terhadap perempuan bukanlah hal yang wajar karena tindakan ini dapat merugikan pihak-pihak tertentu, oleh karena itu di era digital sekarang ini penting untuk dihilangkan dan diakui keburukannya oleh masyarakat demi tercapainya kesetaraan. Sudah selayaknya diasumsikan sebagai saran bagi perempuan sebagai pengguna media sosial jika mereka harus memprioritaskan niat mereka untuk konten media, terutama nilai moral masyarakat.
Kata kunci: Seksual, Objektifikasi, Perempuan