bluuebunny/crossref_metadata_2025_split huggingface dataset:
Efficacy of Accelerated Vaccination Against Hbv to Achieve Antibody Formation in Multiple Sclerosis Patients Receiving Anti-Cd20 Therapy
Authors: Koc Emine Rabia , Turan Omer Faruk , Saridas Furkan , Menguc Bedirhan , Minaz Sema Nur , Ozkaya Guven 
Published: October 2023

Abstract

Aim:
Ocrelizumab is a monoclonal antibody that has been approved for use in both relapsing–remitting multiple sclerosis (RRMS) and primary progressive multiple sclerosis (PPMS). Since ocrelizumab acts on B cells, it also affects humoral immunity, thus reducing the vaccine response. In this study, we aimed to elucidate the relationship between the antibody response following rapid vaccination against hepatitis B virus (HBV) in multiple sclerosis (MS) patients receiving ocrelizumab treatment, and the time of vaccination.

Materials and Methods:
A total of 220 MS patients were included in this retrospective analysis. The patients’ baseline HBV serostatuses (HbsAg, Anti-HbsAb, Anti-HbcAb), previous drug history for MS, whether they were vaccinated against HBV in the past, vaccination status before or after ocrelizumab treatment, and protective antibody titers according to vaccination times, occult HBV incidence and initiation of antiviral treatment were evaluated.

Results:
Forty-nine percent of MS patients using ocrelizumab were not vaccinated against HBV. The patients were divided into three groups according to their vaccination status as: individuals vaccinated in the past (7.3%, n = 16), vaccinated before treatment (4.5%, n = 10), and vaccinated after treatment (22.3%, n = 49). The antibody titers of the patients in the 6th month after ocrelizumab treatment were measured as 78 mIU/ml, 193 mIU/ml, and 0, respectively. The number of patients with occult HBV infection was 38.

Conclusion:
In patients with a suspected diagnosis of MS, HBV serostatus should be evaluated at the beginning and if necessary, patients should be vaccinated in the early period. Vaccinating patients at least 1 month before initiating multiple sclerosis treatment is more effective in terms of protective antibody formation.
Darier Disease with Acrokeratosis Verruciformis of Hopf and their Aggravation on Lithium Therapy for Bipolar Disorder
Authors: Sharma Avinash , Saini Brij Kishore , Jain Suresh Kumar , Kushwaha Ramesh Kumar 
Published: October 2023

Abstract
Darier disease (DD) and acrokeratosis verruciformis of Hopf are rare autosomal dominant skin disorders. Both are caused by a single gene mutation, i.e., ATP2A2 located on chromosome 12, which is expressed in the skin and brain. However, both the diseases are clinically and histopathologically distinct. DD is associated with many neuropsychiatric conditions such as depression, bipolar disorder (BPD), and seizures. Lithium is commonly used as a mood stabilizer in psychiatry and is reported to aggravate DD. We report a case of a 17-year-old female with DD and acrokeratosis verruciformis with associated with BPD Type 1 presenting with an aggravation of skin lesions after starting lithium therapy.
PENGARUH MOTIVASI KERJA, PENGALAMAN, DAN PELATIHAN DALAM MENINGKATKAN KINERJA KARYAWAN PADA RESTAURANT DI BALI
Authors: Ribek Pande Ketut , Imbayani I Gusti Ayu , Sulistyawati Ni Putu Dian 
Published: October 2023

ABSTRAK Peningkatan kinerja memberikan dampak positif dalam pencapaian tujuan perusahaan sehingga manajemen harus mempelajari sikap dan prilaku para karyawan dalam perusahaan. Dalam meningkatkan kinerja karyawan perusahaan harus dapat mengetahui faktor-faktor yang dapat mempengaruhi kinerja. Penelitian ini bertujuan untuk mengetahui pengaruh motivasi kerja, pengalaman kerja dan pelatihan kerja tehadap kinerja karyawan pada restaurant tendan korean BBQ di Bali. Penelitian ini dilakukan di Restaurant Tendan Tendan Korean BBQ dengan total sampel sebanyak 30 orang karyawan dengan sampling jenuh. Teknik analisis regresi linier berganda.Berdasarkan hasil penelitian dinyatakan bahwa motivasi kerja berpengaruh positif dan signifikan terhadap kinerja karyawan, pengalaman kerja berpengaruh positif dan signifikan terhadap kinerja karyawan, pelatihan kerja berpengaruh positif dan signifikan terhadap kinerja karyawan pada Restaurant Tendan Korean BBQ di Bali Kata Kunci : Motivasi Kerja, Pengalaman Kerja, Pelatihan Kerja, Kinerja Karyawan.
Production of ice-nucleating particles (INPs) by fast-growing phytoplankton
Authors: Thornton Daniel C. O. , Brooks Sarah D. , Wilbourn Elise K. , Mirrielees Jessica , Alsante Alyssa N. , Gold-Bouchot Gerardo , Whitesell Andrew , McFadden Kiana 
Published: October 2023

Abstract. Sea spray aerosol contains ice-nucleating particles (INPs), which affect the formation and properties of clouds. Here, we show that aerosols emitted from fast-growing marine phytoplankton produce effective immersion INPs, which nucleate at temperatures significantly warmer than the atmospheric homogeneous freezing (−38.0 ∘C) of pure water. Aerosol sampled over phytoplankton cultures grown in a Marine Aerosol Reference Tank (MART) induced nucleation and freezing at temperatures as high as −15.0 ∘C during exponential phytoplankton growth. This was observed in monospecific cultures representative of two major groups of phytoplankton, namely a cyanobacterium (Synechococcus elongatus) and a diatom (Thalassiosira weissflogii). Ice nucleation occurred at colder temperatures (−28.5 ∘C and below), which were not different from the freezing temperatures of procedural blanks, when the cultures were in the stationary or death phases of growth. Ice nucleation at warmer temperatures was associated with relatively high values of the maximum quantum yield of photosystem II (ΦPSII), an indicator of the physiological status of phytoplankton. High values of ΦPSII indicate the presence of cells with efficient photochemistry and greater potential for photosynthesis. For comparison, field measurements in the North Atlantic Ocean showed that high net growth rates of natural phytoplankton assemblages were associated with marine aerosol that acted as effective immersion INPs at relatively warm temperatures. Data were collected over 4 d at a sampling station maintained in the same water mass as the water column stabilized after deep mixing by a storm. Phytoplankton biomass and net phytoplankton growth rate (0.56 d−1) were greatest over the 24 h preceding the warmest mean ice nucleation temperature (−25.5 ∘C). Collectively, our laboratory and field observations indicate that phytoplankton physiological status is a useful predictor of effective INPs and more reliable than biomass or taxonomic affiliation. Ocean regions associated with fast phytoplankton growth, such as the North Atlantic during the annual spring bloom, may be significant sources of atmospheric INPs.
Global patterns and drivers of phosphorus fractions in natural soils
Authors: He Xianjin , Augusto Laurent , Goll Daniel S. , Ringeval Bruno , Wang Ying-Ping , Helfenstein Julian , Huang Yuanyuan , Hou Enqing 
Published: October 2023

Abstract. Most phosphorus (P) in soils is unavailable for direct biological uptake, as it is locked within primary or secondary mineral particles, adsorbed to mineral surfaces, or immobilized inside of organic material. Deciphering the composition of different P forms in soil is critical for understanding P bioavailability and its underlying dynamics. However, widely used global estimates of different soil P forms are based on a dataset containing few measurements in which many regions or soil types are unrepresented. This poses a major source of uncertainty in assessments that rely on these estimates to quantify soil P constraints on biological activity controlling global food production and terrestrial carbon balance. To address this issue, we consolidated a database of six major soil P “forms” containing 1857 entries from globally distributed (semi-)natural soils and 11 related environmental variables. These six different forms of P (labile inorganic P (Pi), labile organic P (Po), moderately labile Pi, moderately labile Po, primary mineral P, and occluded P) were measured using a sequential P fractionation method. As they do not represent precise forms of specific discrete P compounds in the soil but rather resemble operational pools, we will now refer to them as P pools. In order to quantify the relative importance of 11 soil-forming variables in predicting soil P pool concentrations and then make further predictions at the global scale, we trained random forest regression models for each of the P pools and captured observed variation with R2 higher than 60 %. We identified total soil P concentration as the most important predictor of all soil P pool concentrations, except for primary mineral P concentration, which is primarily controlled by soil pH and only secondarily by total soil P concentration. When expressed in relative values (proportion of total P),
the model showed that soil pH is generally the most important predictor for
proportions of all soil P pools, alongside the prominent influences of soil
organic carbon, total P concentration, soil depth, and biome. These results
suggest that, while concentration values of P pools logically strongly depend on soil total P concentration, the relative values of the different
pools are modulated by other soil properties and the environmental context.
Using the trained random forest models, we predicted soil P pools'
distributions in natural systems at a resolution of 0.5∘×0.5∘. Our global maps of different P pools in soils as well as the pools' underlying drivers can inform assessments of the role of natural P availability for ecosystem productivity, climate change mitigation, and the functioning of the Earth system.
Session 1: Aeroelastic modelling
Authors: Cesnik Carlos E. S. , Ritter Markus , Hilger Jonathan , Riso Cristina 
Published: October 2023

**Chair: Rafael Palacios (Imperial College)**Modeling Challenges and Opportunities for Aircraft with High-Aspect-Ratio Wings (HARW)We highlight the differences that come in the requirements for the modeling of aircraft with HARW. We will also discuss possible solutions for some of the outputs of interests that makes this class of aircraft different than the more traditional ones.Nonlinear Aeroelastic Analyses and Structural Optimization in Aircraft Preliminary DesignThe presentation covers different topics related to nonlinear aeroelastic analysis in aircraft preliminary design. Methods for the calculation of steady (maneuver) and unsteady (gust) loads including geometrical nonlinearities - which are required for the structural optimization - are discussed. Furthermore, one of our goals is to consider aeroelastic and structural nonlinearities as early in the aircraft (preliminary) design and structural optimization process as possible.
Impact of Model Complexity on Aeroelastic Predictions for Very Flexible WingsThis presentation covers a comprehensive study on the impact of model complexity on aeroelastic predictions for wings with levels of flexibility relevant to high-aspect-ratio-wing aircraft. Metrics of interest include natural frequencies, static structural and aeroelastic response, and instability onsets. The presentation ends with an outlook on areas where additional investigations are necessary to advance our understanding of how to appropriately model, analyze, and simulate very flexible wings to support the development of future high-aspect-ratio-wing aircraft.
Propriedades sensoriais e físico-químicas de patê de frango com teor reduzido de sal
Authors: Gelinski Flávia Renata , Rodrigues Bruna Magusso , Hokama Lais Maluf , Santos Elisvânia Freitas dos , Candido Camila Jordão , Novello Daiana 
Published: October 2023

O objetivo deste estudo foi de verificar a aceitabilidade sensorial de patês de frango elaborados com diferentes teores de cloreto de sódio (NaCl), cloreto de potássio (KCl) e glutamato monossódico (GM) e avaliar a composição físico-química do produto. Na Etapa 1, avaliaram-se cinco formulações de patê, com adição de NaCl e KCl (de 0 a 1 %). Na Etapa 2, foram avaliadas as mesmas formulações com adição de GM (0,2 %). Na Etapa 1, não houve diferença significativa para os atributos aparência, aroma, textura e cor. Contudo, para as características sabor, aceitação global e intenção de compra a amostra contendo KCl (1 %) recebeu menores notas do que aquela sem adição de KCl. Na Etapa 2, os produtos apresentaram aumento na aceitabilidade após adição de GM. Foi possível reduzir 75 % de sódio nos patês de frango (NaCl - 0,25 % e KCl - 0,75 %), e obter amostra com aceitação sensorial semelhante ao produto padrão e maior possibilidade de adição de KCl, principalmente em conjunto com o GM.
ESTIMASI BOBOT BADAN BERDASARKAN DIMENSI TUBUH SAPI MADURA BETINA
Authors: Zoelfan Fahmi , Umar Malikah , Agustini Desi Maharani 
Published: October 2023

Sapi Madura sebagai salah satu ternak lokal di Indonesia yang memiliki kesempatan baik untuk dikembangkan, mengingat tingkat kontribusinya yang relative tinggi dalam memenuhi kebutuhan daging nasional. Akan tetapi kelemahan dan keterbatasan sapi Madura terdapat pada pertumbuhan yang cukup lambat, hal tersebut dikarenakan manajemen pemberian pakan yang kurang tepat sehingga sapi Madura tumbuh tidak sesuai dengan potensi genetiknya (Umar, 2016). Tujuan dari penelitian ini adalah untuk mengetahui keeretan hubungan dimensi tubuh terhadap bobot badan sapi Madura betina. Materi penelitian menggunakan sapi Madura betina mulai dari PI0 sebanyak 25 ekor, PI1 sebanyak 9 ekor, PI2 sebanyak 55 ekor, PI3 sebanyak 34 ekor, PI4 sebanyak 58 ekor.. Metode dan Teknik pengambilan sampel menggunakan purposive sampling dengan menggunakan metode surve. Variabel yang di ukur adalah panjang badan, tinggi badan dan lingkar dada. Hasil penelitin rataan lingkar dada, tinggi badan, panjang badan dan bobot badan sapi Madura betina yaitu dapat diketahui bahwa semakin tua sapi maka rata-rata lingkar dada semakin bertambah. Nilai korelasi bobot badan dengan lingkar dada pada PI0 sebesar 0,91, PI1 sebesar 0,82, PI2 sebesar 0,85, PI3 sebesar 0,86 dan PI4 sebesar 0,85. Dengan demikian lingkar dada dapat dijadikan sebagai alat penduga bobot badan karena memiliki keeratan dimensi.
USAHA TERNAK AYAM PETELUR DI DESA GUGUL KECAMATAN TLANAKAN KABUPATEN PAMEKASAN
Authors: Sholehah Tantriatus , Sumiarsih Dedeh Ritta 
Published: October 2023

Usaha ternak ayam petelur merupakan salah satu usaha yang dapat menjadi sumber pendapatan utama bagi peternak. Kecamatan Tlanakan memiliki populasi ternak ayam terbanyak dan berasal dari Desa Gugul. Populasi ternak ayam petelur sebesar 85.000 ekor, berasal dari hasil 45 peternak ayam petelur. Pada awal 2022 jumlah peternak ayam petelur tinggal 30 usaha ternak. Penurunan jumlah ternak ayam petelur saat ini menyebabkan hasil telur yang dihasilkan dan pendapatan peternak di Desa Gugul berkurang. Tujuan penelitian ini untuk mengetahui karakteristik peternak dan usaha ternak ayam petelur dan tingkat pendapatan peternak ayam petelur di Desa Gugul Kecamatan Tlanakan. Metode penelitian adalah deskriptif kualitatif, dengan objek seluruh usaha ternak ayam petelur yang ada di Desa Gugul Kecamatan Tlanakan Kabupaten Pamekasan terdiri dari sebanyak 10 peternak dan usaha ayam petelur yang masih aktif. Karakteristik peternak meliputi: umur, tingkat pendidikan, tanggungan keluarga, jenis gender, motivasi beternak, lama beternak. Karakteristik usaha ternak meliputi: skala usaha, curahan waktu dan pengetahuan beternak. Tingkat keuntungan dianalisis dari biaya produksi, penerimaan, pendapatan, BCR, dan RCR. Hasil penelitian menunjukkan bahwa karaketristik peternak ayam petelur di Desa Gugul berusia 31- 60 tahun, dengan pekerjaan utama sebagai petani dan peternak; tanggungan keluarga berkisar antara 3 - 6 orang; berpendidikan SD - SMA; lama beternak kurang dari 10 tahun sebanyak 50% dengan motivasi yang kuat sebagai peternak. Karateristik usaha ternak: 60% peternak memiliki skala usaha kurang dari 500 ekor, 30% memiliki 500- 1200 ekor, dan 10 % memiliki skala usaha sebesar 20.000 ekor. Curahan waktu terhadap usaha ternak selama kurang dari 5 jam/hari sebanyak 90%. Pengetahuan tentang usaha ternak 90% diperoleh dari belajar sendiri. Komponen biaya total terdiri dari biaya tetap dan biaya variabel dan biaya total sebesar 1.82%, dan 98.18%. Penerimaan berkisar antara Rp 2.016.656,00 hingga Rp 628.603.711,00; Keuntungan antara Rp -17.754.711.289,00 hingga Rp -63.626.291,00 dengan BCR antara -0.99 hingga -0.39; sedangkan R/C rasio antara 0,01 dan 0,61. Hasil penelitian menunjukkan bahwa usaha ternak saat ini masih merugi akibat biaya pakan dan bibit yang tinggi, sedangkan produksi dan harga telur yang rendah
Working with women affected by children’s social care involvement in pregnancy and early motherhood: Insights from recent Birth Companions work
Authors: Miller Brunton Katherine , Kitchen Kirsty 
Published: October 2023

Children’s social care (CSC) involvement during pregnancy and the first two years of a child’s life – the period known as the ‘1001 critical days’ – can have a significant impact on the mental health and wellbeing of both mothers and infants. By putting bonding and attachment between mothers and their babies at risk, this can pose long-term implications for children’s emotional and psychological development.Drawing on findings from Birth Companions’ recent projects with women with lived experience of CSC involvement, this article offers insight into the mental health impacts of assessment and/or care proceedings during the first 1001 days.The article also outlines key principles for all those working with women in these circumstances, published in the form of theBirth Companions Birth Charter for women with involvement from children’s social care(2023c). This aims to embed improved practice across all systems and services working with women with CSC involvement.Key recommendations focus on the significance of trauma-informed care for women, and the centralisation of pregnancy and early motherhood in multi-agency practice. Birth Companions is calling for this to be driven forward in the form of a joint national health and social care pathway for pregnant women and mothers of infants who are subject to pre-birth or parenting assessment, or child protection proceedings, to guide the care and support they receive up to their child’s second birthday.
Working in partnership to support trauma informed care for children, young people and their families in North Yorkshire
Authors: Carter Shevaun , Hadgett Laura , Phillips Katy , Snodgrass Clare 
Published: October 2023

The Psychologically Informed Partnership Approach (PIPA) is a partnership between North Yorkshire Council (NYC) and Tees, Esk and Wear Valleys NHS Foundation Trust (TEWV). PIPA aims to provide a flexible, psychological and trauma-informed service to meet a wide range of needs of vulnerable children across Children and Families Services (C&FS) within North Yorkshire.PIPA consists of Clinical and Forensic Psychologists, and Advanced Practitioners working across NYC. The service considers the individual needs, complexities and experiences of children, young people, family members and practitioners, whilst also holding in mind broader systemic and organisational perspectives. This paper outlines how PIPA applies a range of models and frameworks to support innovative, non-blaming approaches with children, young people and their families, and the outcome of this approach thus far.A variety of measures are used to evaluate how PIPA involvement has influenced a range of outcomes for children, young people and families, as seen in theOutcomes and Feedback section. Two case studies are also included to demonstrate how this approach works in practise.The paper concludes with reflections on our learning and recommendations for similar practices to be embedded across other children and families’ services in the country.
Reviews of Books
Authors: G. J. A. K. , F. A. , H. J. P. , L. E. V. 
Published: October 2023

JOURNEY INTO IRELAND. By W. A. Poucher. Country Life, Ltd., London. 128 pp. (30pp. text, 90 pp. illustrations). 30s. 11x 81/2 in.THE GEOLOGY OF IRELAND. By J. K. Charlesworth. Oliver and Boyd, Edinburgh and London, 1953. 276 pp. 25s.THE GEOGRAPHY OF TOWNS, by A. E. Smailes. Hutchinson's University Library, London, 1953. 166 pp., 22 maps. 8s. 6d.THE RESTLESS ATMOSPHERE, by F. K. Hare. Hutchinson's University Library, London, 1953. 192pp. 8s. 6d
Reviews of Books
Authors: D. G. L. , G. J. A. K. , H. T. J. , A. J. H. , A. J. H. , A. F. H. A. , A. F. H. A. , O. A. R. , G. J. A. K. 
Published: October 2023

COASTAL CHANGES. By W. W. Williams. London : Routledge and Kegan Paul, 1960. 5 ½ × 8 ½ inches, xviii and 220 pages. Maps, plates, and diagrams. 28s.DUBLIN : FUNKTIONEN UND ENTWICKLUNG, by Reinhard Stewig. Kiel : Schriften des Geographischen Instituts der Universität, Band xviii. Heft 2, 1959. Pp. 254. 9 ½ × 6 ½ in. DM 10, 50.A SOCIAL GEOGRAPHY OF BELFAST. Emrys Jones. 8 3/4 × 5 ½ in. xiv + 299 pp. Oxford University Press, 1960. 35s.THE LARGE SCALE MAPS OF THE BRITISH ISLES, 1596–1850. E.M. Rodger. 9 3/4 × 6in. xx + 52 pp. Oxford : Bodleian Library, 1960.RAUMFORSCHUNG: 25 JAHRE RAUMFORSCHUNG IN DEUTSCHLAND. Academie für Raumforschung und Landes‐planung. 10 × 7 in. 534 pp. Bremen. 1960. 42 DM.A GEOGRAPHY OF NORDEN. Axel SFmme (ed.). 360 pp. Oslo : J.W. Cappelens Forlag. 1960.WELSH RURAL COMMUNITIES. Elwyn Davies and Alwyn D. Rees (eds.). xi + 254pp. Cardiff : University of Wales Press 1960. 15s.LANDSCAPE DRAWING. Geoffrey E. Hutchings. Methuen, London. 1960. 134pp. 30s.SURVEY OF IRELAND, 1 : 250,000. Sheet 3 : Ireland, West. Dublin: Ordnance Survey Office, 1960. 32 × 24 in. 2s. 6d. flat, 3s. 6d. folded.
Reviews of Books
Authors: F. A. , F. T. W. , A. J. H. , G. J. A. K. , G. J. A. K. , O. A. R. , S. J. A. , B. R. A. , A. J. H. , D. G. L. , B. R. A. , G. J. A. K. , H. J. P. , P. E. M. 
Published: October 2023

HISTORICAL GEOLOGY OF IRELAND. J. K. Charlesworth. 9×6 in. xxiii + 565 pp. Oliver and Boyd: Edinburgh and London. 1963. 84s.JACKSON, John N., Surveys for Town and Country Planning, London, Hutchinson University Library, 1963, 15s.THE IRISH BORDER AS A CULTURAL DIVIDE. M. W. Heslinga. 225 pp. Assen. 1962.SHELL GUIDE TO IRELAND, by Lord Killanin and Michael V. Duignan. London: The Ebury Press, 1962. 478 pp. 9 3/4 × 6 in. 45s.IRELAND BY THE IRISH, edited by Michael Gorman. London: Galley Press Ltd., 1963. 162 pp. 9 3/4 × 7 in. 30s.MARINE CARTOGRAPHY IN BRITAIN. A history of the sea chart to 1855. A. H. W. Robinson. 11¼ × 9 in. 222 pp., 30 text figures, 42 photographic plates. Leicester: Leicester University Press, 1962. £5. 5s.VEGETATION AND SOILS, A WORLD PICTURE, by S. R. Eyre. London: Edward Arnold, 1963. pp. 324. 36/‐.MORPHOGENESIS OF THE AGRARIAN CULTURAL LANDSCAPE, (ed.) S. Helmfrid. Published as Geografiska Annaler, Vol. XLIII, 1961, Number 1–2. Stockholm. Pp. 1–328.NOTIONS ESSENTIELLES DE GÉOGRAPHIE ÉCONOMIQUE, by Jean Mérigot and Roland Froment, Volume one, Sirey, Paris, 1963; 555 pp., 54 illustrations.THE MONSOON. Pierre Pédelaborde. 8 × 5½ in. xii + 196 pp. Methuen, London, 1963, 21s.ON THE MARGINS OF THE GOOD EARTH. The South Australian Wheat Frontier 1869–1894. D. W. Meinig. Murray, London, 1963. 231 pp. 35s.INDEX TO AUSTRALIAN RESOURCES MAPS OF 1940–59. Canberra : Dept. of National Development, 1961. 241 pp. 9 × 6½ in.BRITISH LANDSCAPES THROUGH MAPS. Numbers 1 to 5. The Geographical Association. Price 4/6 each.‘SAMPLE STUDIES’. The Geographical Association. 1962. Price 4/6.