bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hybridity in Non‐profits: Innovating for Social Value Creation
Authors: Logue Danielle , Edwards Melissa , McAllister Gillian 
Published: January 2025

AbstractNon‐profits face rising pressure to secure funding and innovate for increasingly complex social problems, while cognizant that failed innovations could produce consequential societal harm. In a longitudinal case study, we apply a social innovation lens to examine how a non‐profit experiments with hybridity. Applying such a lens foregrounds mechanisms of social value creation, capture and distribution and reveals how non‐profits can move beyond managing tensions and instead look to reframe hybridity as innovation. Our study, based as it is in social innovation, brings a focus to organizational dynamics and processes and reveals how organizational responses to hybridity occur in mission and operations and, importantly, in strategy. This reconceptualization of hybridity makes a theoretical contribution in bridging literature on hybridity and social innovation, anchoring in management and strategy. It also makes a significant empirical contribution in reconceptualizing hybridity for practitioners and in showing how hybridity may then be viewed not as a threat to non‐profit values and traditions and not as an ongoing tension to resolve, but rather as a process to innovate and amplify social value and impact.
Adverse Reactions to Cosmetic Fillers in the Oral and Maxillofacial Region: Clinico‐Pathological, Histochemical, and Immunohistochemical Characterization
Authors: Tetzner Ana Cristina , Viana Laura Regina Mendes , Abreu Lucas Guimarães , Mendonça Elismauro Francisco , Arantes Diego Antônio Costa , Vasconcelos Ana Carolina Uchoa , Gomes Ana Paula Neutzling , Nonaka Cassiano Francisco Weege , Alves Pollianna Muniz , Tapia Roberto Onner Cruz , Mesquita Ricardo Alves , de Sousa Sílvia Ferreira , Silva Tarcília Aparecida , Caldeira Patrícia Carlos 
Published: January 2025

ABSTRACTBackgroundCosmetic injections are increasing, as their complications, which can be misdiagnosed as neoplastic lesions. This study aimed to detail clinical, pathological, histochemical, and immunohistochemical features of adverse reactions to cosmetic fillers in the oral and maxillofacial region.MethodsSamples were retrieved from five pathology laboratories. Hematoxylin–eosin (H&E), Alcian Blue, Sirius Red, and Toluidine blue stains were performed, as well as immunohistochemistry for CD68, CD3, and CD20. H&E was evaluated under polarization. Descriptive statistics were performed.ResultsTwenty‐three cases were included. Polymethyl‐methacrylate was the most common material. Most reactions affected women, lips and were asymptomatic, with a variable time of evolution, presenting as nodules. Materials had different shape and size on H&E. Giant cells were commonly found, except in silicone and hyaluronic acid. Foreign‐body granuloma was frequent in polymethyl‐methacrylate. Calcium hydroxyapatite and poly‐L‐lactic acid were refractile under polarized light. Hyaluronic acid and polyacrylamide hydrogel were metachromatic by Toluidine blue. Alcian blue was positive in all cases of hyaluronic acid. Mast cells were detected in all materials, except hyaluronic acid and polyacrylamide hydrogel. Eosinophils were rarer than mast cells. Numerous CD68‐positive cells were seen in all cases. All cases had CD3‐positive cells, with variable amounts. CD20 was scant or negative in most cases.ConclusionsAn evident macrophage reaction is observed in all aesthetic fillers, frequently associated with giant cell formation. Despite similarities, there are specific features of each material and the host response that assist the correct histopathological diagnosis. Immunohistochemistry for CD68 and Toluidine blue stain are useful in doubtful cases.
A New Empirical Model of the Determinants of Sickness and the Choice Between Presenteeism and Absence
Authors: Denis Théo , Lanfranchi Joseph 
Published: January 2025

ABSTRACTThis article revisits the association between employment characteristics, working conditions, and the annual duration of sickness presenteeism or absence using a French representative survey. Our novel estimation method controls for endogenous participation, as working conditions can affect employees' likelihood of illness separately from the decision to stay at home or work ill. We use a copula approach to model the link between illness and the duration of presenteeism and absence. Without correcting for endogenous participation, our estimates would be biased, and the determinants of sickness absence or presenteeism incorrectly identified. This work helps to highlight firm policy instruments that protect health and affect the choice between sickness presenteeism and absence.
Autonomous construction framework for crane control with enhanced soft actor–critic algorithm and real‐time progress monitoring
Authors: Xiao Yifei , Yang T. Y. , Xie Fan 
Published: January 2025

AbstractWith the shortage of skilled labors, there is an increasing demand for automation in the construction industry. This study presents an autonomous construction framework for crane control with enhanced soft actor–critic (SAC‐E) algorithm and real‐time progress monitoring. SAC‐E is a novel reinforcement learning algorithm with superior learning speed and training stability for lifting path planning. In addition, robotic kinematics and a control algorithm are implemented to ensure that the crane can autonomously execute the lifting path. Last, novel hardware communication interfaces between robot operating system and building information modeling (BIM) are developed for real‐time construction progress monitoring. The performance of the proposed framework was demonstrated using a robotized mobile crane to stack concrete retaining blocks. The results show that the proposed framework can be effectively used to execute the retaining block construction using the robotized mobile crane with real‐time construction update in the BIM platform.
Prevalence and Treatment Patterns of Anaemia in Individuals With Chronic Kidney Disease Across Asia: A Systematic Review and Meta‐Analysis
Authors: Kim Dana , Lee Joshua , Toyama Tadashi , Liyanage Thaminda , Woodward Mark , Matsushita Kunihiro , Hooi Lai Seong , Lin Ming‐Yen , Iseki Kunitoshi , Jha Vivekanand , Wong Muh Geot , Jun Min ,   For the Asian Renal Collaboration
Published: January 2025

ABSTRACTAimAnaemia is a significant complication of chronic kidney disease (CKD). However, its prevalence and treatment patterns in Asia are poorly understood. We sought to quantify prevalence of anaemia and its treatment in people with CKD across the region.MethodsMEDLINE and Embase (inception to 2023) were systematically searched for observational studies of adults with CKD conducted in Asia that reported the prevalence of anaemia or its treatment. Additional relevant unpublished data were obtained from national experts. Summary estimates of the prevalence of anaemia and its treatment were determined using a random‐effects meta‐analysis according to country and study‐specific CKD inclusion criteria.ResultsEighty‐six studies from 10 Asian countries reported data on 1 342 121 participants. The overall prevalence of anaemia in individuals with CKD was 42% (95% CI 33%–52%), with wide variation (12%–57% in studies including all CKD stages; 21%–96% in studies limited to individuals with kidney failure). Anaemia prevalence progressively increased with more advanced CKD (80% in Stage 5). Studies reporting data on anaemia treatment, particularly in early CKD, were limited. The prevalence of erythropoietin‐stimulating agents (ESAs) and iron therapy was 40% (95% CI 24%–58%) and 21% (95% CI 14%–31%), respectively (ESA: 7%–29% in CKD, 63%–95% in kidney failure; iron: 6%–26% in CKD, 15%–88% in kidney failure).ConclusionOur findings indicate a significant, but widely varying, prevalence of anaemia and its treatment in people with CKD in Asia. Substantial variability in data availability and collection highlights the need for standardised reporting to facilitate the development of regionally relevant strategies for anaemia management in CKD.
A First Case Report of Autoimmune Acquired Factor V Deficiency After Severe Acute Respiratory Syndrome Coronavirus 2 mRNA Vaccination at the Time of Initiating Haemodialysis
Authors: Tasaki Ayako , Fukuda Akihiro , Kudo Akiko , Nishikawa Emiko , Koumatsu Nobuchika , Wada Megumi , Okita Jun , Maruo Misaki , Uchida Hiroki , Nakata Takeshi , Itani Kazuhito , Shibata Hirotaka 
Published: January 2025

ABSTRACTA 73‐year‐old Japanese man with chronic kidney disease had no history of abnormal clotting or bleeding. Six days after receiving his third dose of the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccine (BNT162b2; Pfizer/BioNTech), blood tests showed a marked prolongation of the prothrombin time‐international normalised ratio and activated partial thromboplastin time, as well as a decrease in factor V (FV) activity. Three months later, he required dialysis owing to worsening heart and renal failure. After supplementation with FV, a flexible double‐lumen catheter was inserted, and haemodialysis was initiated without the use of anticoagulants. The patient was found to be positive for FV inhibitors and was diagnosed with autoimmune acquired factor V deficiency (AiFVD). AiFVD is a rare autoimmune disease in which factor V inhibitors decrease FV activity. The patient did not undergo immunosuppressive therapy because he did not have severe bleeding symptoms, and he is currently able to continue dialysis without causing fatal bleeding. FV inhibitors can be induced by bovine thrombin, surgery, and infection, but have also been detected after SARS‐CoV‐2 infection. The development of various acquired coagulation factor inhibitors has been reported after SARS‐CoV‐2 infection or vaccination, but there have been no reports of AiFVD due to SARS‐CoV‐2 vaccination. To the best of our knowledge, this is the first report of AiFVD probably associated with SARS‐CoV‐2 vaccination. Although AiFVD is rare, physicians should be aware of its possibility after SARS‐CoV‐2 vaccination.
Cardiac Vagal Efficiency Is Enhanced by Percutaneous Auricular Neurostimulation in Adolescents With Nausea: Moderation by Antidepressant Drug Exposure
Authors: Kolacz Jacek , Roath Olivia K. , Lewis Gregory F. , Karrento Katja 
Published: January 2025

ABSTRACTObjectivesPercutaneous electrical nerve field stimulation (PENFS) is an effective treatment for disorders of gut–brain interaction (DGBI), proposed to influence vagal pathways. Cardiac metrics such as respiratory sinus arrythmia (RSA) and vagal efficiency (VE) can noninvasively assess parasympathetic output. Commonly used antidepressant drugs inhibit vagal signaling and may interfere with PENFS. This study examined immediate effects of active compared to sham PENFS on cardiac vagal function in adolescents with chronic nausea with and without concurrent drug therapy.Materials and MethodsParticipants (n = 84) were randomized to active (3.2 V, 1–10 Hz) or sham PENFS within an 8‐week prospective, double‐blind clinical trial. Subjects underwent posture challenges to elicit a vagal response before and after PENFS device placement mid‐way through the study. RSA, mean heart period (HP), and VE were calculated from electrocardiogram recordings. Exposure to antidepressant drugs was recorded.ResultsThe mean (SD) age was 15.61 (2.07) years (83% female). Fifty percent were treated with antidepressants. PENFS neurostimulation enhanced VE in patients without antidepressant exposure (mean increase after PENFS stimulation =7.56 [95% CI: 0.26, 14.86], d = 0.30, 17% increase) but not in those treated with antidepressants (mean change = −5.30 [95% CI:−14.28, 3.68]). Sham PENFS did not produce significant VE changes regardless of medication use (both p > 0.40). There were no significant effects on RSA or HP.ConclusionsAcute enhancement of cardiac VE is demonstrated with PENFS in patients not exposed to chronic antidepressant drug therapy. Findings indicate that VE is a sensitive metric for rapid assessment of PENFS effects but raise concern for possible interaction or interference by standard of care medications.Trial Registration: Clinicaltrials.gov #: 1064187–2
Effects of Porphyromonas gingivalis Outer Membrane Vesicles (OMVs) on Macrophages in Periodontitis
Authors: Zhang Shuyi , Jiao Yao , Liu Siyan , Liu Yitong , Liu Yi 
Published: January 2025

ABSTRACTObjectiveTo review the effect of outer membrane vesicles (OMVs) of the periodontal pathogen Porphyromonas gingivalis (P. gingivalis) on macrophages during periodontitis development.MethodLiterature pertaining to P. gingivalis OMVs and macrophages was reviewed and discussed, with a focus on the immunomodulatory effects of P. gingivalis OMVs on macrophages.ResultsP. gingivalis OMVs affect the recognition, phagocytosis, polarization, and apoptosis functions of macrophages. However, information on their antigen‐presenting effect remains lacking, and further research is required for clinical applications.ConclusionP. gingivalis OMVs can influence the development of periodontitis through immune modulation of macrophages; however, further research is required to provide novel ideas for the prevention and treatment of periodontitis.
Arabidopsis Ankyrin‐Repeat Protein Kinase ANK‐PK2 Negatively Regulates Salt Tolerance by Mediating Degradation of the Sugar Transporter Protein STP11
Authors: Ma Qijun , Xu Shuo , Hu Shi , Zuo Kaijing 
Published: January 2025

ABSTRACTSoluble sugars provide energy sources required for plant growth and development. They also act as osmoprotectants to improve the salt tolerance of plants. However, molecular mechanism underlying the negative regulation of soluble sugar accumulation in plants under salt stress conditions remains unknown. In this study, we investigated the functions of ankyrin‐repeat kinase 2 (ANK‐PK2) that regulates soluble sugar content in Arabidopsis under salt stress. ANK‐PK2 interacts with and phosphorylates the sugar transporter protein 11 (STP11) under salt stress. Phosphorylated STP11 is easier to degrade, and its glucose‐transporting ability and soluble sugar accumulation are inhibited. The ank‐pk2 mutant exhibited increased salt tolerance. The salt‐sensitive phenotype of the mutant stp11 was recovered through a dephosphorylation mutation that changed Thr227 in STP11 to Ala227. Our results revealed a novel molecular mechanism underlying salt stress adaptation in Arabidopsis, which ANK‐PK2 negatively regulates salt tolerance by phosphorylating and subsequently decreasing the transport activity of STP11 to balance the cellular soluble sugar content in Arabidopsis.
“Rising Women”: Evidence From China's Agricultural Mechanization
Authors: Pan Rui , Gao Mengfei , Ji Yueqing 
Published: January 2025

ABSTRACTThe transformation of agricultural machinery technology in China has revolutionized traditional farming practices and reshaped gender relations. Utilizing data from five waves of the China Family Panel Studies (CFPS) spanning 2014 to 2022, this paper empirically investigates the impact of mechanization on women's empowerment. The findings reveal that mechanization significantly enhances women's empowerment scores, especially in the economically advanced eastern regions and among farming households. Rigorous endogeneity analysis and robustness tests affirm the reliability of these results. Mechanism analysis uncovers that mechanization promotes women's empowerment through labor migration and increased female relative income. Additionally, further analysis indicates that mechanization influences marital dynamics, notably by lowering wives' evaluations of their spouses. This study not only enriches the body of research on agricultural mechanization but also provides a novel perspective on the evolution of gender relations within rural families.
An insect †Archaeopteryx: Cretaceous amber fossil elucidates the evolution of complex host detection and ovipositor mechanisms in parasitoid woodwasps (Hymenoptera: Orussoidea)
Authors: Vilhelmsen Lars , Boudinot Brendon E. , Hammel Jörg U. , Nakamine Hiroshi , Yamamoto Shûhei 
Published: January 2025

AbstractWe describe †Cretovelona orussopteryx n. gen. & sp., a female orussoid from mid‐Cretaceous Kachin amber. We examine the fossil with synchrotron scanning and integrate it into an existing morphological data set for Orussoidea. †Cretovelona is placed as sister to crown group Orussoidea by Bayesian phylogenetic analyses. It is unique in displaying a combination of plesiomorphic (e.g. 12 antennomeres, exposed ovipositor sheaths, partly internalized ovipositor that does not extend further than anterior part of abdomen) and apomorphic characters (e.g. antenna with club, fore tarsus 3‐segmented) that display intermediate stages in the evolution of the host detection mechanism and the fully internalized ovipositor in extant Orussidae. The wing venation of †Cretovelona is even more reduced than observed in extant Orussidae, likely correlated with the small body size (<2 mm). Tracing the changes in body size across the orussoid tree indicates that the stem group underwent a size reduction event in the Cretaceous, something that might have influenced character evolution in for example wing venation and internalization of the ovipositor. †Cretovelona is a rare example of a transitional fossil that elucidates the evolution of complex features when adapting to a highly specialized lifestyle, in this case detecting and targeting hosts deep inside wood. We propose to recognize only the family Orussidae within Orussoidea. Orussidae comprises the crown group Orussoidea, including all Cenozoic fossils described so far. The stem group taxa, all Mesozoic fossils, are not assigned to any specific family within Orussoidea. Zoobank Registration: urn:lsid:zoobank.org:pub:397F76A5‐7467‐4BCA‐9963‐6A380EC05200.
Design and Implementation of a Low-Cost IoT-Based Real-Time Emission Monitoring System for a Thermoelectric Generator-Integrated Biomass Cookstove
Authors: Pandit Shankar , Das Dulal Chandra , Das Biplab , Newar Pranjal Prasad 
Published: January 2025

Abstract
More than 2 billion people globally depend on biomass for cooking, predominantly using conventional cookstoves. This leads to approximately 4 million annual deaths due to indoor air pollution. Currently, air pollution stands as the biggest environmental health challenge worldwide, having harmful effects on human health, climate, and ecosystems. These health risks can be reduced by improving stove design and combustion characteristics. This article focuses on the design and development of a low-cost IoT-based real-time emission monitoring system (LIEMS) integrated with a thermoelectric generator-integrated biomass cookstove (TIBC). The TIBC is designed to support multi-fuel use, improve user-friendliness, reduce emissions, and enhance overall efficiency. Here, the emission performance evaluation is facilitated by the LIEMS, which monitors pollutants such as particulate matter PM2.5, PM1.0, PM10, carbon monoxide (CO), carbon dioxide (CO2), and volatile organic compounds (VOCs) while also capturing temperature profiles of the cookstove. The LIEMS system is powered entirely by the thermoelectric generator, eliminating the need for an external power source. Built on the ESP-WROOM-32 development board and integrated with the ThingSpeak IoT platform, the system enables real-time data visualization, email alerts for unsafe pollutant levels, and air quality management strategies. Validation results showed measurement discrepancies of ±5.42% for PM2.5, ±5.46% for PM1.0, ±5.49% for PM10, ±23.68% for CO, ±2.38% for CO2, and ±2.17%, ±8.57%, and ±2.17% for the cookstove's hot-side temperature (Thot) and ±8.57% for its cold-side temperature (Tcold). This new integration of IoT technology with TIBC offers a reliable and user-friendly solution for real-time indoor air quality monitoring, advancing household air quality management and sustainability.
Identification Method of Remaining Oil Potential Area Based on Deep Learning
Authors: Zhao Beichen , Yao Yuedong , Xiao Zheyu , Wei Yafei , Liu Hanze , Huang Jiacheng , Tian Ya-Peng , Wang Jianchao 
Published: January 2025

Abstract
Efficiently classifying potential areas of remaining oil is essential for enhancing the recovery in high water cut reservoir. The distribution of remaining oil is complex and challenging to mobilize due to temporal evolution and spatial variation in long-term waterflood development. Currently, reservoir classification relies on manual experience and unsupervised machine learning, both of which have limitations. Manual classification is constrained by human understanding, leading to inaccuracies, while unsupervised learning lacks adherence to reservoir theory, resulting in a possible lack of physical interpretability. This article introduces the Beluga whale optimization and the improved temporal convolutional network (BWO-ITCN) model, a novel prediction classification model that combines intelligent classification with reservoir theory constraints. The structure of the ITCN model was improved by changing the serial structure to the parallel pooling structure, in order to extract the features of time series data. The BWO-ITCN model incorporates expert experience by considering five dynamic and one static indicators for evaluating potential areas. It aims to identify remaining oil potential areas by learning the evaluation indicators in spatial variations and temporal evolution. The BWO algorithm enhances the classification precision by optimizing hyperparameters, particularly, blending samples. The experimental results demonstrate that the BWO-ITCN model achieves an accuracy of 94.25%, a precision of 94.1%, a recall rate of 93.82%, and an F1-score of 93.83%. Notably, the overall accuracy of a spatiotemporal model is higher than a nonspatiotemporal model. This autonomous classification model effectively addresses the challenges in classifying potential areas, simplifies the process, and offers valuable insights for development.