bluuebunny/crossref_metadata_2025_split huggingface dataset:
Precise colocalization of sorghum's major chilling tolerance locus with Tannin1 is due to tight linkage drag not antagonistic pleiotropy
Authors: Schuh Anthony , Felderhoff Terry J , Marla Sandeep , Morris Geoffrey P 
Published: October 2023

Abstract
Chilling tolerance in crops can increase resilience through longer growing seasons, drought escape, and nitrogen use efficiency. In sorghum (Sorghum bicolor [L.] Moench), breeding for chilling tolerance has been stymied by coinheritance of the largest-effect chilling tolerance locus, qSbCT04.62, with the major gene underlying undesirable grain proanthocyanidins, WD40 transcriptional regulator Tannin1. To test whether this coinheritance is due to antagonistic pleiotropy of Tannin1, we developed and studied near-isogenic lines (NILs) carrying chilling tolerant haplotypes at qCT04.62. Whole-genome sequencing of the NILs revealed introgressions spanning part of the qCT04.62 confidence interval, including the Tannin1 gene and an ortholog of Arabidopsis cold regulator CBF/DREB1G. Segregation pattern of grain tannin in NILs confirmed the presence of wildtype Tannin1 and the reconstitution of a functional MYB-bHLH-WD40 regulatory complex. Low-temperature germination did not differ between NILs, suggesting that Tannin1 does not modulate this component of chilling tolerance. Similarly, NILs did not differ in seedling growth rate under either of two contrasting controlled environment chilling scenarios. Finally, while the chilling tolerant parent line had notably different photosynthetic response from the susceptible parent line – including greater non-photochemical quenching before, during, and after chilling – the NIL responses match the susceptible parent. Thus, it is likely that tight linkage drag, not pleiotropy, underlies the precise colocalization of Tan1 with qCT04.62 and the qCT04.62 quantitative trait nucleotide lies outside the NIL introgressions. Our findings suggest breaking linkage at this locus would advance chilling tolerance breeding in sorghum and the identification of a novel chilling tolerance regulator.
Assessment of the incidence of lateral incisive canals in a Japanese population using dental cone-beam computed tomography
Authors: Ogawa Atsushi , Ikeda Yunosuke , Kawai Tadashi , Izumisawa Mitsuru , Fujimura Akira , Yamada Hiroyuki 
Published: October 2023

Abstract
Purpose
This observational study employed dental cone-beam computed tomography (CBCT) to evaluate the incidence and anatomical features of neurovascular structures within the lateral incisive canal (LIC).
Methods
CBCT images obtained from 221 patients were evaluated to determine the presence, diameter, and length of the LIC.
Results
In this study, LICs were identified in 24.4% of the included CBCT images (bilaterally in 61.1% and unilaterally in 38.9%). One LIC was observed in 57.4% of cases, while two and three LICs were observed in 16.7% and 14.8% of cases, respectively, with only a minority of cases displaying four to six LICs. The mean diameters of the LIC and foramen were 0.7 ± 0.3 mm (0.3 − 1.8) and 0.8 ± 0.4 mm (0.3–2.3), respectively. Moreover, the mean length of the LIC was 8.9 ± 4.1 mm (2.1–32.3). The incidence of LICs (24.4%) in our study was lower than that reported in previous CBCT studies on Asian populations. However, it is important to note that there may be regional differences in the incidence of anatomical structures, even among individuals of the same race.
Conclusion
Identification of the LIC through CBCT can provide valuable information for surgical procedures involving the anterior maxilla.
Population structure and pest dynamics of invasive whiteflies, Rugose spiraling whitefly (Aleurodicus rugioperculatus) and Bondar nesting whitefly (Paraleyrodes bondari) on Oil Palm
Authors: Subbanna A. R.N.S. , S. Sai Tejasri , Shil Sandip , CH. Chinnabbai , N. Emmanuel 
Published: October 2023

Abstract
Globalization of trade occasionally resulted in unwanted biological invasions incurring huge monetary losses. The recent alien whitefly complex on palms in India viz., rugose spiraling whitefly (RSW), Aleurodicus rugioperculatus Martin and bondar nesting whitefly (BNW), Paraleyrodes bondari Peracchi are well dispersed and established. Although both are coexisting on oil palm, the distribution patterns and population dynamics are studied using population counts of four fronds at four directions and at three locations per frond (base middle and tip) taken over four months (February, March, April and May, 2022) on 36 palms of a garden. The results revealed that both species preferred tip leaflets of frond with no significant difference between middle and tip leaflets in case of RSW and with a clear significant preference of tip leaflets in case of BNW. Specific preference of palms, population variation over time and locations are revealed. The reduction in population over time was prevalent in RSW. These results help in understanding the population dynamics and designing effective management tools against both the pests as unified program.
Effects of the grass in different phenological periods on rumen fermentation and gastrointestinal tract bacteria community in grazing yak on the Qinghai-Tibetan Plateau
Authors: Guo Tongqing , Wang Xungang , Zhang Qian , Wang Yalin , Wei Lin , Li Na , Xu Xianli , Liu Hongjin , Hu Linyong , Zhao Na , Xu Shixiao 
Published: October 2023

Abstract
Background: In this study, we investigated the effects of grass in different phenological periods on ruminal fermentation, serum biochemical indices, and gastrointestinal tract microbes in grazing yak on the Qinghai-Tibetan Plateau. A total of eighteen female freely grazing yaks with an average age of 3 years old and a body weight of 130 ± 19 kg were selected. According to the plant phenology periods, yaks were randomly allocated to one of three treatments: (1) regreen periods group (RP, n = 6); (2) grassy periods group (GP, n = 6); (3) hay periods group (HP, n = 6). At the end of the experiment, the blood, rumen fluids, and rectal contents were collected to perform further analysis.
Results: Yak in the GP group increased the concentration of total volatile fatty acid (TVFA), acetate, urea acid (UA), glucose (GLU), triglyceride (TG), cholesterol (CHO), high density lipoprotein (HDL), low density lipoprotein (LDL), the abundance of Prevotella in the rumen, and the abundances of Rikenellaceae_RC9_gut_group, Eubacterium_coprostanoligenes_group, and Prevotellaceae_UCG-004 in the gut (P < 0.05). However, yak in the HP group increased the concentrations of isobutyrate, isovalerate, valerate, creatinine (CREA), the abundance of Eubacterium_coprostanoligenes_group in the rumen, and the abundances of Romboutsia and Arthrobacterin the gut (P < 0.05).
Conclusions: Based on the results of rumen fermentation, serum biochemical, differential biomarkers, and function prediction, yak increased the digestion of carbohydrates via gastrointestinal tract microbes with the grass regreen and grassy. However, the gastrointestinal tract of yaks increased the risk of microbe disorders and host inflammation with the grass wither.
Indocyanine green endoscopic evaluation of pituitary stalk and gland blood flow in craniopharyngiomas
Authors: Makino Ryutaro , Fujio Shingo , Sugata Jun , Yonenaga Masanori , Hanada Tomoko , Higa Nayuta , Yamahata Hitoshi , Hanaya Ryosuke 
Published: October 2023

Abstract
Objective: We aimed to assess the use of indocyanine green (ICG) fluorescence endoscopy to evaluate pituitary blood flow in craniopharyngioma resection and its possible impact on intraoperative decisions regarding pituitary stalk processing.
Methods: Patients with craniopharyngiomas who had undergone transsphenoidal surgery since March 2021, when an ICG endoscope was introduced at Kagoshima University Hospital, were included in the study. When targeted tumor removal was approaching completion, 10 mg of ICG was administered intravenously, and blood flow in the pituitary stalk and gland was evaluated. Subsequently, ICG signals and endocrinological status before and after surgery were evaluated retrospectively. Pituitary stalk and gland blood flow was evaluated as sufficient (++), weakly positive (+), and no signal (-).
Results: Ten patients with craniopharyngiomas underwent transsphenoidal surgery using an ICG endoscope (mean age 56.6 ± 14.2 years; 40% male). Among the eight patients in whom the pituitary stalk was preserved, pituitary function with sufficient signal on the stalk was intact in two. Two other patients with weakly positive stalk and sufficient pituitary gland signals showed intact function or minimal pituitary dysfunction. Four patients had impairments in more than three axes with poor ICG signals in the stalk or pituitary gland. Two patients underwent pituitary amputation because of high tumor invasion and lack of ICG signal in the stalk after tumor removal, resulting in panhypopituitarism.
Conclusion: A negative ICG signal is likely to indicate postoperative loss of pituitary function. Craniopharyngioma surgery using ICG endoscopy may be useful for predicting endocrine prognosis and improving tumor outcomes.
High-precision matching algorithm for multi-image segmentation of micro animation videos in mobile network environment
Authors: Su Yehui , Djenouri Youcef 
Published: October 2023

Abstract
In the mobile network environment, the accuracy of related image matching algorithms is affected by factors such as bandwidth uncertainty and channel interference, resulting in significant limitations in image feature matching. This article designs a high-precision matching algorithm for multi-image segmentation of micro animation videos in mobile network environments. Fully denoise micro animation video images using 2D High Density Discrete Wavelet Transform (HD-DWT), and apply fixed block count segmentation to process micro animation video images; Using Harris algorithm to complete image corner detection and obtain corner features of sub images; In the K-means clustering algorithm, SIFT feature vectors are divided into clusters and paired with the nearest neighbor cluster in another sub image to form a sub image matching pair, completing block based sub image matching; Combine all sub image matching results to obtain video image matching results, and use the Improved Random Sampling Consistency (RANCAS) algorithm to remove incorrect matching during the matching process, improving matching accuracy. The experimental results show that the designed algorithm can effectively reduce image noise, improve image quality, and generate a large number of matching pairs in mobile network environments. After the application of the designed algorithm, the production effect of micro animated videos in mobile networks can be significantly improved.
Comprehensive Bioinformatics Analysis of Hub Genes in Ischemic Heart Failure and Atrial Fibrillation
Authors: Zhou Meimei , Xu Youkang , Zhang Lili , Yang Yushan , Zheng Jiejiao 
Published: October 2023

Abstract
Background
Atrial fibrillation (AF) and heart failure (HF) frequently coexist and mutually influence each other. The association between AF and the subtype of HF, Ischaemic heart failure (IHF), remains insufficiently described, despite their high prevalence. Hence, comprehending their underlying pathophysiological mechanisms and identifying new therapeutic targets are urgently needed.
Methods
Datasets for HF (GSE57338) and AF (GSE128188) were acquired from the Gene Expression Omnibus (GEO) database. Intersecting these sets generated common differentially expressed genes (DEGs) for further analyses, including Gene Ontology (GO) enrichment, Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, protein-protein interaction (PPI), and hub gene identification. Subsequently, the HF dataset (GSE116250) and AF dataset (GSE2240) were utilized to confirm the expression of the hub genes.
Results
The study identified 20 common DEGs. Among them, 10 hub genes (SFRP4, FMOD, HAPLN1, LTBP2, SVEP1, BCL6, ANPEP, CD38, ATRNL1, and BEX1) were found to be associated with the co-occurrence of HF and AF.
Conclusion
The identified 10 hub genes can serve as potentially valuable biomarkers for IHF and AF. Enrichment analysis reveals that these potential biomarkers are significantly associated with extracellular matrix, nicotinate, and nicotinamide metabolism, providing a foundational target for the joint diagnosis and treatment of the two diseases.
A nomogram to predict survival in patients older than 65 years with rectal cancer: A SEER-based population study
Authors: Nong Sikai , Huang Huan , Mo Qiyan , Zhang Weiming 
Published: October 2023

Abstract
Background: There has been no construction of nomograms specifically geared towards pblueicting the prognosis of older patients with rectal cancer. Our objective was to create a nomogram that can accurately pblueict the chances of cancer-specific survival (CSS) and overall survival (OS) for older patients with rectal cancer,stratifying them into distinct risk groups.
Methods: Data of older than 65 years with rectal cancer from the Surveillance, Epidemiology, and End Results (SEER) database between 2000 and 2020 were extracted.
Results: A total of 12,780 patients were collected in order to identify the independent prognostic factors for cancer-specific survival (CSS) and overall survival (OS) and construct nomograms. The factors included age, sex, race,year of diagnos, marital status, grade, tumor size, CEA, T classification, N classification, Months from diagnosis to treatment, surgery, chemotherapy, and radiation. LASSO regression was used for this purpose. The results showed that grade, chemotherapy, and months from diagnosis to treatment were identified as independent prognostic factors for OS, while grade, chemotherapy, and tumor size were identified as independent prognostic factors for CSS. The concordance index of the CSS nomogram was 0.609 (95% confidence interval [CI], 0.598-0.619) in the training cohort and 0.682 (95%CI, 0.665-0.698) in the validation cohort. The concordance index of the OS nomogram was 0.697 (95%CI, 0.686-0.708) in the training cohort and 0.605 (95%CI, 0.589-0.621) in the validation cohort.
Conclusion: Caution should be taken when administering adjuvant therapy after surgery in older patients with rectal cancer,as we have developed and validated a new pblueictive nomogram for CSS and OS.
Ophthamological Conditions Among Elderly Patients Attending a Private Eye Care Facility in Malawi.
Authors: Banda Owen , Ogbonna Grace , Mzumara Thokozani 
Published: October 2023

Abstract
Background: The elderly comprises the fastest-expanding age group globally, with the greatest increase occurring in developing countries. The elderly populace is prone to develop various ocular morbidities.
Purpose: To determine the distribution of ocular morbidities among the elderly population visiting a private eye care facility in Malawi.
Methods: This was a retrospective cross-sectional study conducted at St John’s Hospital in Mzuzu, Malawi. We retrieved data from the hospital’s ophthalmic outpatient registry from January to December 2021. A non-probability census sampling technique was used to recruit 52 elderly patients. Data analysis were done employing SPSS (v.26)
Results: Less males 25 (48.1%) than females 27 (51.9%) had ocular morbidities. Refractive error 21 (40.4%) was the most prevalent ocular morbidity followed by cataract 13 (25.0%), pinguecula 6 (11.5%), and glaucoma 4 (7.7%). No sex and age association were found with any of the ocular morbidities (p>0.05).
Conclusion: The pattern of eye diseases is endemic to the country. More resources should be targeting main causes of preventable blindness including refractive error and cataracts.
Hygro-Photo-Thermoelastic Solid Cylinder under Moisture and Thermal Diffusivity with Two Temperatures
Authors: Singh Kulvinder , Kaur Iqbal , Craciun Eduard-Marius 
Published: October 2023

Abstract
A new model for the simulation of moisture and thermal diffusivity in a semiconducting solid cylinder according to the Moore-Gibson-Thompson-Photo-Thermal (MGTPT) equation with two-temperature (Conducive and Thermodynamic temperature) theory of thermoelasticity has recently been presented. The purpose of this study is to investigate the photo-thermoelasticity of an infinite semiconducting solid cylinder rotating with the boundary surface being subjected to a laser pulse with a variable heat flux. For this purpose, the mathematical model is solved by using the Laplace transform technique in the transformed domain. The numerical inversion of the mathematical model yields all the physical parameters in the physical domain, such as displacement components, conductive temperatures, thermal stresses, and carrier densities. In order to clearly illustrate the effects of reference moisture with two temperatures, a graphic representation of all these parameters is generated by using the MATLAB software. The results of this study will be useful in further enhancing the behavior of semiconductors under these dynamic loading conditions and in hence, improve their performance in various applications. Thus, the model provides an effective way to model the moisture and thermal diffusivities of the solid cylinder in order to better understand phenomena occurring in a broad range of semiconductor devices and more effectively design them.
Data-driven Bayesian inference for stochastic model identification of nonlinear aeroelastic systems
Authors: McGurk Michael , Lye Adolphus , Renson Ludovic , Yuan Jie 
Published: October 2023

Abstract

The objective of this work is to propose a data-driven Bayesian inference framework to efficiently identify parameters and select models of nonlinear aeroelastic systems. The framework consists of the use of Bayesian theory together with advanced Kriging surrogate models to effectively represent the limit cycle oscillation response of nonlinear aeroelastic systems. Three types of sampling methods, namely Markov Chain Monte-Carlo, Transitional Markov Chain Monte-Carlo, and the Sequential Monte-Carlo sampler, are implemented into Bayesian model updating. The framework has been demonstrated using a nonlinear wing flutter test rig. It is modelled by a two-degree-of-freedom aeroelastic system and solved by the harmonic balance methods. The experimental data of the flutter wing is obtained using control-based continuation techniques. The proposed methodology provided up to 20 % improvement in accuracy compared to conventional deterministic methods. Transitional Markov Chain Monte-Carlo was identified as the optimal choice of the sampling method for stochastic model identification. In selecting alternative nonlinear models, multi-modal solutions were identified that provided a closer representation of physical behaviour suggesting the mathematical model requires further modification.
Microplastics in seafood: Consumer preferences and valuation for mitigation technologies
Authors: Barrientos Manuel , Lavín Felipe Vásquez , Oliva Roberto D. Ponce , Nayga Rodolfo M. , Gelcich Stefan 
Published: October 2023

Abstract
Microplastics, an emerging pollutant, have garnered widespread attention due to potential repercussions on human health and the environment. Given the critical role of seafood in food security, growing concerns about microplastics might be detrimental to meeting future global food demand. This study employs a discrete choice experiment to investigate Chilean consumers' preferences for technology aimed at mitigating microplastic levels in mussels. Using a between-subjects design with information treatments, we examined the impact of informing consumers about potential human health and environmental effects linked to microplastics pollution on their valuation for the technology. We found that the information treatments increased consumers’ willingness to pay for them. Specifically, consumers’ willingness to pay for mussels with a 90% depuration efficiency certification is around US$ 4. The provision of health impact information increased the price premium by 56%, while the provision of environmental information increased it by 21%. Furthermore, combined health and environmental information significantly increased the probability of non-purchasing behavior by 22.8% and the risk perception of microplastics for human health by 5.8%. These results emphasize the critical role of information in shaping consumer preferences and provide evidence for validating investment in research and development related to microplastic pollution mitigation measures.
Discussion on stress assumption and yield criterion determination rule of the PSM
Authors: Ruibin Mei , li Bao , Lihao Chen , Xianghua Liu 
Published: October 2023

Abstract
As one of the main methods to solve deformation mechanics, the principal stress method (PSM) is widely used in stress analysis and technology optimization of metal forming processes. The stress assumption, yield criterion and boundary conditions have been investigated according to the frequently asked questions in teaching and application of the PSM, and then the determination rule was proposed and described. The yield criterion, boundary conditions and calculated results should keep the corresponding relationship with the initial stress assumption of the micro-element. The stress distribution and load in the plane deformation of the rectangular workpiece was successfully solved using the PSM based on the rule proposed and FEM. The average relative error is 8.3% between the predicted loads by FEM and PSM, and the stress and load predicted by PSM are in good agreement with the FEM. Furthermore, the same calculated results of stress were obtained under different conditions, indicating that the rule proposed is reliable and practical significance for and application of the PSM.
A causal analysis of the impact of early antibacterial therapy on ICU patient outcomes for sepsis
Authors: Moghadam Hamed Markazi , Moghaddam Nader Markazi 
Published: October 2023

Abstract
This paper addresses the global issue of sepsis, a major cause of ICU-related deaths, by focusing on the impact of early antibiotic administration on patient outcomes. The Surviving Sepsis Campaign guidelines recommend timely antimicrobial treatment, but the association with mortality remains uncertain, and other outcomes like hospital and ICU stay length are understudied. We employ the Double Machine Learning (DML) method and the eICU Collaborative Research Database to analyze the relationship between early antibiotics and patient outcomes. Although initial summary statistics imply a substantial influence of the timing of antibacterial therapy on patient outcomes, indicating earlier treatment with reduced mortality rates and shorter hospital and ICU stays, our causal model refines these results. It shows that quicker initiation of therapy primarily affects hospital and ICU length of stays, while showing no significant impact on mortality rates. Given the substantial hospital costs associated with septicemia, the findings hold implications for cost savings.
OS DESAFIOS DA GESTÃO ESCOLAR FRENTE À PANDEMIA: UMA ANÁLISE DO CAMPO
Authors: Couto Bueno Eliane , Rosa Gama Maria Eliza 
Published: October 2023

Este estudo tem por objetivo apresentar um panorama sobre os impactos da pandemia de covid-19 sobre a gestão educacional, tendo por objeto de análise a produção acadêmica e científica do período de 2020-2021, disponível no repositório Google Acadêmico. A análise do material aponta para questões que afetaram diretamente a atuação de gestores, tais como: a precariedade do ensino remoto em relação ao presencial; o baixo envolvimento das famílias na devolução das atividades às escolas; a necessidade de se investir mais em recursos tecnológicos a fim de contemplar a todos os estudantes; e com destaque a pressão sofrida pelos gestores para a instrumentação de seu quadro de professores para que correspondessem às novas exigências do ensino remoto, através de formações para a correta utilização das ferramentas digitais, a adaptação das aulas ao modelo digital e os desafios da alfabetização à distância.