bluuebunny/crossref_metadata_2025_split huggingface dataset:
Distribution of Aedes mosquito species along the rural–urban gradient in Lambaréné and its surroundings
Authors: Bikangui Rodrigue , Boussougou-Sambe Stravensky Terence , Saidou Mahmoudou , Ngossanga Barclaye , Doumba Ndalembouly Ange Gatien , Djida Ynous , Ayong More  , Beh Mba Romuald , Abe Haruka , Ushijima Yuri , Borrmann Steffen , Lell Bertrand , Yasuda Jiro , Adegnika Ayola Akim 
Published: October 2023

Abstract
Background
Aedes albopictus and Aedes aegypti are known for their potential as vectors of dengue (DENV) and chikungunya (CHIKV) viruses. However, entomological surveys are mostly carried out during epidemics. In Gabon where outbreaks of both viruses have occurred, there is no vector control program targeting these arboviruses. Therefore, we assessed the presence of Aedes species along a rural–urban gradient in Lambaréné (Gabon) and its surroundings and determined ecological factors associated to their presence.

Methods
An entomological survey was conducted in Lambaréné and its surrounding rural areas. Mosquitoes were collected with aspirators around human dwellings, and ecological and environmental data were collected from each study area. Morphological identification keys were used to identify Aedes species. RNA was extracted from pools of female mosquitoes and amplified by RT-qPCR to detect the presence of DENV and CHIKV.

Results
Overall, the most common vector collected was Aedes albopictus (97%, 4236/4367 specimens), followed by Aedes aegypti (3%, 131/4367). Albopictus vectors was more abundant in the rural area (Wilcoxon signed-rank test, Z = 627, P = 0.043) than in the urban area. In the urban area, a higher number of mosquitoes (45%) were recorded in the economic zone (zone 3) than in the historical and administrative zones (zone 1 and 2). In the rural area, the proportions of species numbers were significantly higher along the south rural transect (92%) compared to the north rural transect (Wilcoxon signed-rank test, Z = 43, P ˂ 0.016). We also noted a high abundance of vectors in environments characterized by monocultures of Hevea brasiliensis (Hevea) and Manihot esculenta (cassava) (Kruskal–Wallis H-test, H = 25.7, df = 2, P < 0.001). Finally, no mosquito pools were positive for either DENV or CHIKV.

Conclusion
Aedes albopictus was the dominant vector across the study sites due to its high invasiveness capacity. This presence re-affirms the potential for local transmission of both DENV and CHIKV, as indicated previously by serological surveys conducted in our study area, even though no transmission was detected during the current study. These findings underscore the need for regular arbovirus surveillance in the study region, with the aim of supporting vector control efforts in the event of outbreaks.

Graphical Abstract
Analyses of actions which cause anterior cruciate ligament injuries in the national basketball association players: YouTube-based video analyses
Authors: Saito Takanobu , Matsumura Natsuki , Kawamoto Shinichi , Doi Naoki , Aoyama Tomoki , Nagai-Tanima Momoko 
Published: October 2023

Abstract
Background
Anterior cruciate ligament (ACL) injuries are among the most common injuries in the National Basketball Association (NBA), and it is important to investigate the actual nature of the injury because it can impair a player’s performance after returning to the game. Although the moment of injury has been investigated, the details of the movements and circumstances leading to injury in basketball games are unknown. This study aimed to clarify the actions leading to ACL injuries and to investigate their characteristics, based on YouTube video analyses of the NBA players.

Methods
Players with ACL injuries in the NBA were identified through web-based research over 10 seasons (2011/2012–2021/2022, through October 2021), with 29 recorded videos of ACL injuries in the NBA. Actions were categorized based on basketball-specific gestures, and determined whether the player was in contact with an opponent or not and, if so, the location of the contact was analyzed focusing on two time points: at the injury frame (IF) and one step before the injury frame (IF-1). The “injury leg” timing was counted for each of the first and second steps after ball possession.

Results
The majority (68.2%) of ACL injury occurred during the 2 steps phase (only two steps can proceed after ball retention in basketball, so we defined them as two steps) in the offense action, and most notably during the first step (80.0%). 73.3% of players who were injured during the 2 steps phase got contact to an area other than the knee (Indirect contact) at the IF-1, with 81.8% of contact being located in the upper body contralateral to the respective knee injury. The probability of players with ACL injuries during the 2 steps at the IF-1 who got Indirect contact was statistically significantly greater than those who got no contact with other players (p = 0.042).

Conclusions
We argue that including pre-injury play and contact falls into the novelty category. Through YouTube-based video analyses, this study revealed that ACL injuries tend to be characterized by specific types of actions, the timing of contact, and the location of contact in NBA players.
Factors influencing the degree of disability in patients with neuromyelitis optica spectrum disorders
Authors: Shi Lili , Li Dawei , Zhang Yunxiu , Wang Jinling , Fu Jingxuan , Liu Xia , Wang Peichang 
Published: October 2023

Abstract
Objective
To investigate the factors influencing the degree of disability in patients with neuromyelitis optica spectrum disorder (NMOSD) and provide evidence for disease monitoring and clinical intervention.

Methods
Eighty-four patients with NMOSD at Xuanwu Hospital Capital Medical University were enrolled in this retrospective study. Before treatment, blood was collected from all patients, and their expanded disability status scores were assessed.

Results
Of the 84 patients assessed, 66 (78.57%) had an expanded disability status scale score < 7, and 18 (21.43%) had scores ≥ 7. The univariate analysis showed that the total bilirubin (TBil), cerebrospinal fluid albumin (CSF ALB), cerebrospinal fluid immunoglobulin G (CSF IgG), QALB, and QIgG levels in the group with scores ≥ 7 were significantly different from those with scores < 7 (P < 0.05). In addition, Spearman’s correlation analysis showed a significant correlation between ALB and expanded disability status scores in patients with NMOSD (P < 0.05), and the multivariate logistic regression analysis showed that TBil was an independent factor influencing the degree of disability in patients with NMOSD (P < 0.05). The receiver operating characteristic curve was constructed using TBil values; the area under the curve of TBil was 0.729 (P < 0.01), and the best cut-off value was 11.015 g/L. Its sensitivity in predicting the severity of disability in NMOSD patients was 51.5% while its specificity was 88.9%.

Conclusion
TBil is an independent factor that influences the severity of disability in patients with NMOSD. In addition, ALB is closely related to NMOSD severity, and some factors associated with the BBB are significantly increased in severely disabled NMOSD patients.
The effectiveness and safety of botulinum toxin injections for the treatment of sialorrhea with Parkinson's disease: a systematic review and meta-analysis
Authors: Yang Chun-Lan , Huang Jia-Peng , Tan Ying-chao , Wang Ting-ting , Zhang Han , Qu Yun 
Published: October 2023

Abstract
Background
Botulinum toxin (BoNT) injection is an important adjunctive method to treat sialorrhea. The purpose of this systematic review was to analyze the effect and safety of BoNT injections in the intervention of sialorrhea with Parkinson’s disease (PD).

Methods
We searched PubMed, Web Of Science (WOS), Scopus, Cochrane CENTRAL, and Embase from inception until April 2022. Randomized controlled trials or randomized crossover trials comparing BoNT with placebo in sialorrhea with PD were eligible. PRISMA guidelines were used to carry out the meta-analysis. The Drooling Severity Frequency Scale (DSFS) score and the number of adverse events (AEs) were the primary and secondary outcomes, respectively. Standardized mean differences (SMDs) and risk differences (RDs) are used to express continuous and categorical outcomes, respectively. Heterogeneity among these studies was evaluated using I2 tests. We used the GRADE tool to assess the certainty of evidence (COE).

Results
Eight articles involving 259 patients compared BoNT injections with a placebo for PD with sialorrhea. This meta-analysis showed a significant reduction in DSFS scores between BoNT injections and placebo (SMD=-0.98; 95% CI, -1.27 to 0.70, p<0.001; COE: high). This meta-analysis showed a significant difference in AEs between BoNT injections and placebo (RD=0.15; 95% CI, 0.05 to 0.24, p=0.002; COE: low).

Conclusions
The pooled results suggest that BoNT injections have some effect on DSFS scores with sialorrhea caused by PD. There are also mild adverse events, which generally recover within a week or so. The results indicate that BoNT injection is one of the treatments for sialorrhea caused by PD, but we need to pay attention to adverse events. In addition, the follow-up time was extended to observe oral hygiene, ulceration or dental caries, and digestive function.

Trial registration
Our review protocol was registered on PROSPERO (42021288334).
Dispersal of juvenile Barrow’s goldeneyes (Bucephala islandica) mirrors that of breeding adults
Authors: Forstner T. M. , Boyd W. S. , Esler D. , Green D. J. 
Published: October 2023

AbstractBarrow’s goldeneyes across western North America have been shown to have a high degree of subpopulation independence using several data types. However, evidence for structured populations based on mitochondrial DNA, band recoveries, and tracking of adults is discordant with evidence from autosomal DNA. We used satellite tracking data from both juveniles and adults marked on natal and breeding grounds, respectively, in British Columbia, Canada to evaluate the hypothesis that male-biased juvenile dispersal maintains genetic panmixia of Pacific Barrow’s goldeneyes otherwise structured by migratory movements and high winter and breeding site fidelity of adults. We found that juvenile males traveled to overwintering sites located within the range of the overwintering sites of juvenile females, adult males, and adult females. Juvenile males migrated at the same time, travelled the same distance when moving between natal and overwintering sites, and had the same winter dispersion as juvenile females. Although juveniles did not travel with attendant females, all juveniles overwintered within the wintering range of adults. We tracked some juveniles into the following spring/summer and even second winter. Prospecting juveniles of both sexes travelled from their wintering grounds to potential breeding sites in the proximity of Riske Creek and within the bounds of the breeding locations used by adults. Juveniles tracked for more than a year also showed relatively high winter site fidelity. Because Barrow’s goldeneyes pair on wintering grounds, our tracking data are not consistent with the hypothesis that male-biased juvenile dispersal explains the genetic structure in the mitochondrial DNA and panmixia in the autosomal DNA of Barrow’s goldeneye. We suggest that uncommon or episodic dispersal of males might be enough to homogenize autosomal DNA but is unlikely to influence demographic population structure relevant to contemporary population management.
Validity of serum resistin level and Il-6 as prognostic biomarkers of decompensated liver cirrhosis in chronic hepatitis C virus patients
Authors: El-Shayeb Ayman F. , Degheidy Akram A. , El-Mallah Sawsan , Farid John , Abbasy Amany N. 
Published: October 2023

Abstract
Background
Decompensated liver cirrhosis (DLC) is now known as a chronic inflammatory process, evidenced by elevated levels of circulatory pro-inflammatory cytokines and chemokines which in turn lead to the development of more hepatic decompensation and multi-organ failure. Resistin has a pro-inflammatory effect through the production of several cytokines (e.g., IL-1, IL-6, IL-12, and TNF-α) and cell adhesion molecules. Interleukin-6 (IL-6) is a proinflammatory cytokine playing a crucial role in acute phase responses and in regulating immune reactions through activation and differentiation of T and B lymphocytes. The current study aimed to evaluate the value of serum resistin and IL-6 as biomarkers of DLC and their role as prognostic markers of complications in these patients.

Results
This study was conducted on 90 patients divided into three groups: group I—30 patients with compensated cirrhosis (CLC); group II—40 patients with DLC; and group III consisted of 20 healthy controls. Serum resistin and IL-6 levels were statistically significantly higher in patients with DLC compared to patients with CLC at baseline. A cut-off value of > 302 pg/ml for serum resistin was found to discriminate between CLC and DLC with a specificity of 73.33% and sensitivity of 92.50% and a cut-off level of > 31 pg/mL for IL-6 differentiated between the two groups with a sensitivity of 85.0% and specificity of 76.67%. Patients with DLC were followed up for 3 months, 10 patients (25%) passed away, and 19 patients out of the remaining 30 (63.3%) patients developed complications including acute kidney injury, spontaneous bacterial peritonitis, variceal hemorrhage, encephalopathy, and hepatocellular carcinoma. Serum resistin and IL-6 were found to be significantly higher at baseline in those patients who developed complications or mortality after the follow-up period. In addition, there were positive correlations between IL-6 and resistin and MELD-NA and CRP.

Conclusion
Serum resistin and IL-6 could be used as sensitive diagnostic and prognostic biomarkers of decompensated cirrhotic patients.
Does newborn hearing screening cause anxiety among mothers? A cross-sectional study from a tertiary hospital in Malaysia
Authors: Mazlan Rafidah , Abdul Razak Nur Farahain 
Published: October 2023

Abstract
Background
The universal newborn hearing screening (UNHS) has effectively allowed babies with hearing loss to be detected early. However, findings from previous studies indicate that this procedure may adversely induce anxiety among mothers. Therefore, this study aimed to investigate anxiety among mothers whose babies received a hearing screening at a tertiary hospital in Malaysia. A cross-sectional study was conducted on 105 mothers from a tertiary hospital in Kuala Lumpur, Malaysia. Two questionnaires, the Infant Health Concern Scale (IHCS) and State-Trait Anxiety Inventory (STAI), were used to measure the mothers’ worry level on a 4-point Likert scale. Mothers were required to complete the questionnaires twice, before and 4 weeks after discharge, regardless of the hearing screening results.

Results
The STAI scores obtained from mothers whose babies failed the initial screening were significantly higher than mothers whose babies passed. During the initial screening, all mothers rated hearing as the sixth health aspect causing anxiety using the IHCS. However, the ranking fell to 15th place after the second screening. Similarly, mothers whose babies had false positive results also exhibited significantly higher STAI scores and a dropped hearing ranking during rescreening than the initial screening. In addition, mother’s anxiety was not significantly correlated with their education level, family income, or number of births.

Conclusion
Mothers who participated in this study experienced anxiety regardless of their babies hearing screening results. Therefore, the UNHS program must be reviewed to identify appropriate strategies to minimize this negative emotion among mothers.
Evaluation of Hydrophobic Attraction between Polystyrene Layer and Silanated Silica Surface by Atomic Force Microscopy
Authors: Okuda Yuta , Imamura Koreyoshi , Ishida Naoyuki 
Published: October 2023

Abstract
In this study, hydrophobic surfaces were prepared by depositing polystyrene (PS) on a glass substrate using three different methods to measure the interaction forces against a hydrophobized particle by atomic force microscopy. We found that smooth surfaces prepared by spin coating and living radical polymerization generated hydrophobic attraction, whereas uneven surfaces obtained by free radical polymerization produced only steric repulsion, even though they had sufficient hydrophobicity. Based on these results, the origin of the hydrophobic attraction was suggested.
Calixarene-based Cage Compound: Synthesis via Simple Condensation of t-Butylcalix[4]arene with α,ω-Dibromoacetate and Inclusion Complex Formation with Phenol
Authors: Maekawa Hiroyuki , Yajima Tatsuo , Kudo Hiroto 
Published: October 2023

Abstract
Reaction of p-t-butylcalix[4]arene (BCA[4]) with α,ω-dibromoacetate (DBH) afforded a soluble cage compound, BCA[4]-DBH, in high yield. Single-crystal X-ray analysis revealed that BCA[4]-DBH contains a fixed cavity. Examination of host-guest chemistry showed that BCA[4]-DBH forms a 1:1 inclusion complex with phenol, with an association constant (K) of 34.
THE MECHANISM OF MANAGEMENT OF DIGITAL TRANSFORMATION OF ECONOMIC ACTIVITY OF INDUSTRIAL ENTERPRISES
Authors: Arakcheev Dmitry V. 
Published: October 2023

The digital transformation of industry allows a significant increase in labor productivity and the growth of gross domestic product in the manufacturing sector, which ultimately leads to an increase in the welfare of the country’s citizens. However, to solve the existing systemic problems, such as low labor productivity, irrational use of resources, low efficiency of production facilities, etc., it is necessary to implement an effective management mechanism. The implementation of such a mechanism will solve the problems of managing the digital transformation of industrial enterprises, improve the efficiency of production facilities and reduce transaction costs and the complexity of forming responsible cooperative chains.
The purpose is to develop a mechanism for managing the digital transformation of economic activities of industrial enterprises.
Methodology in article: the research methodology is based on existing theoretical developments relating to industrial economics, management issues of industrial complexes, industries, enterprises.
Results: the mechanism for managing the digital transformation of the economic activities of industrial enterprises, representing a set of methods and tools used to change business models and management processes through new paradigms based on digital thinking, revision of organizational processes and digital culture of the industrial enterprise, optimization of the enterprise management system as a whole.
Practical implications: the obtained results can be used in the activities of corporate industrial systems engaged in technological development, digitalization and digital transformation projects.
STUDY OF THE RELATIONSHIP OF CITIZENS’ APPEALS TO THE OPEN PORTAL OF THE GOVERNMENT OF MOSCOW WITH THE SOCIO-ECONOMIC INDICATORS OF THE ADMINISTRATIVE DISTRICT
Authors: Sakhnyuk Pavel A. , Sakhnyuk Tatyana I. 
Published: October 2023

The article discusses the possibilities of studying the state of the social sphere according to the repository of the open data portal of the Government of Moscow for administrative districts and urban districts using business intelligence platforms and intelligent technologies of Data Science and machine learning platforms. The possibilities of using machine learning technologies for business intelligence platforms to identify hidden patterns in order to make informed management decisions are presented.
Purpose – is to familiarize with business intelligence platforms; the use of intelligent BI-platform technologies for monitoring socio-economic indicators.
Method or methodology of the work: the clustering method and statistical research methods were used in the article.
Results: to confirm the hypothesis of a positive relationship between the number of families receiving subsidies in the city of Moscow, in various sections, and the number of appeals of citizens to the open portal of the Government of Moscow
Practical implications: the objective information obtained as a result of monitoring can be used to develop a strategy and make management decisions on the development of districts and improving the quality of life in Moscow
Consenso colombiano de expertos sobre recomendaciones basadas en evidencia para el diagnóstico, tratamiento y seguimiento de enfermedad de Fabry en pediatría
Authors: Baquero Rodriguez Richard , Serrano Gayubo Ana Katherina , Prieto Rivera Juan Carlos , Cardenas Aguilera Juan Guillermo , Rodríguez Cuéllar Carmen Inés , Reina Ávila Maria Fernanda , Estévez Capacho Mayra Alexandra , Mateus Heidy , Valencia González Maylin , Chacón Acevedo Kelly Rocío , Gutiérrez Sepúlveda Maria Paula , Germain Dominique P , Politei Juan , Fainboim Alejandro Fabian , Cerón Rodríguez Magdalena , Cabrera Gustavo , Rodríguez Ibarra Edicson , Carrascal Guzmán Martha Isabel , Martínez Cáceres Lida Esperanza , Ospina Lagos Sandra Yaneth , Trimarchi Hernán , Liern Miguel 
Published: October 2023

Antecedentes: La enfermedad de Fabry (EF) es una enfermedad rara ligada a X secundaria al depósito lisosomal de glicoesfingolípidos debido a la deficiencia de la enzima alfa galactosidasa A (α-Gal A). A pesar de su baja frecuencia, es una condición que afecta la calidad de vida de los pacientes y disminuye su esperanza de vida.
Objetivo: Generar recomendaciones informadas en evidencia para el diagnóstico y tratamiento de pacientes pediátricos (menores de 8 años) con EF.
Métodos: Se realizó una revisión de literatura en bases de datos y literatura gris a partir del 2010, incluyendo guías de práctica clínica, revisiones sistemáticas, estudios primarios. La calidad de evidencia se evalúo de acuerdo con el tipo de evidencia. Las recomendaciones se sometieron a consenso de expertos a través de metodología Delphi modificada. El acuerdo se definió a partir del 80%.
Resultados: A partir del análisis de la evidencia recolectada, se formularon un total de 45 recomendaciones para tamización, diagnóstico y tratamiento de paciente pediátrico con enfermedad de Fabry. El panel revisor estuvo conformado por once expertos en el tema. Las recomendaciones fueron aprobadas con puntuaciones entre 82.3% y 100%.
Conclusiones: Las recomendaciones resultantes del consenso de expertos permitirán la toma de decisiones clínicas y estandarización de la práctica en la atención de pacientes pediátricos con EF a nivel nacional y regional; el diagnóstico temprano y oportuno garantiza una disminución del impacto en la calidad de vida de los pacientes y sus familiares.
Palabras clave: Enfermedad de Fabry, niños, diagnóstico, terapeutica, biomarcadores