bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wood products with advanced solar-to-thermal conversion and
phase change energy storage
Authors: Li Shujun , Dang Ben , Yang Chenhui , Zhou Tao , Yin WeiMing , Liu Shouxin , Zhang Yahui , Xu Ting , Si Chuanling , Li Jian , Chen Zhijun 
Published: November 2023

Abstract
Naturally porous wood, which has the potential to incorporate photothermal absorbers and phase-change materials, has proven to be a valuable scaffold for advanced solar-to-thermal materials and heat management technologies. Nonetheless, the light-absorbing role of lignins, which contain numerous polyaromatic rings, has been largely overlooked. Our study presents a straightforward approach to enhance solar light absorption by wood through in-situ complexation of Fe 3+ with the phenolic hydroxyl groups found in demethylated wood lignin. Phase change energy storage is subsequently achieved by in situ polymerization of polyethylene glycol and hexamethylene diisocyanate to form polyurethane in the cell lumen. This effective combination of solar-to-thermal energy conversion and phase change energy storage exploits the polyaromatic rings of lignin to enhance light-harvesting and utilizes the porous structure of natural wood for the accommodation of phase change materials. The resultant wood shows a real-life application for long-lasting solar-to-thermal conversion, thermal insulation and solar-thermal-electric conversion. This smart wood product provides a cost-effective, highly stable, and easy-to-implement solution for energy conversion and thermal management technologies.
Pan-cancer Analysis for the Prognostic and Immunological Role of CD47: Interact with TNFRSF9 Inducing CD8+T Cell Exhaustion.
Authors: Liang Hongxin , Yao Lintong , Xie Daipeng , Chen Duo , Dai Jinchi , Qiu Hongrui , Wang Huili , Li Hao , Leng Jinhang , Tang Ziming , Jiao Xiuwei , Qiu Liyun , Zhou Haiyu 
Published: November 2023

Abstract

Purpose
The role of CD47 in the effectiveness of immunotherapy has been researched. An understanding of the impact of CD47 on the tumor immune microenvironment, particularly with regard to CD8 + T cells, remains inadequately clarified. Our research focuses on investigating the prognostic and immunological significance of CD47 to gain a deeper understanding of its potential applications in immunotherapy.
Methods
The examination of differential gene expression, prognosis, immunological infiltration, pathway enrichment, and correlation was conducted using various R packages, computational tools, datasets, and cohorts. The notion was validated by the use of single-cell sequencing.
Results
CD47 was expressed in nearly all cancer types, associated with poor prognosis in pan-cancer. The immunological research revealed that CD47 exhibited a stronger correlation with T-cell infiltration as opposed to T-cell rejection in cases of multiple cancers. The cytotoxic CD8 + T cell Top group had a poorer prognosis in the CD47-high group than the CD47-low group showing CD47 might impair CD8 + T cell function. Mechanism exploration found that CD47 differential genes in multiple cancers were enriched in the CD8 + T-cell exhausted pathway. Subsequent analysis of the CD8 TCR Downstream Pathway and correlation analysis of genes further demonstrated the significant involvement of TNFRSF9.
Conclusion
There is a strong correlation between CD47 and the exhaustion of CD8 + T cells, which in turn can facilitate immune evasion by cancer cells, ultimately resulting in a negative prognosis. Hence, the genes CD47 and T-cell exhaustion-linked genes, particularly TNFRSF9, exhibit potential as dual antigenic targets and offer valuable insights into the realm of immunotherapy.
Tocilizumab timing and COVID-19 mortality: a cohort study of early vs late administration
Authors: MacGregor Fiona , O’Prey Alison , Caulfield Carolyn , MacTavish Pamela , Lowrie Richard , Henderson Philip 
Published: November 2023

Abstract
Background
The optimal timing of tocilizumab treatment during the disease course of COVID 19 has yet to be adequately defined in the context of randomised controlled trials, and the effect of tocilizumab on real-world populations remains unclear. We examined the effect of different timing of tocilizumab, on mortality, in a cohort of adults with COVID 19.
Methods
All adults (≥ 18 years old) with confirmed COVID-19 admitted to four hospitals in the West of Scotland between 8th Jan 2021 and 31st March 2021 and who received tocilizumab were included in a retrospective cohort study. Patients were assigned to either an early (day 0 or day 1 of admission) or late (days 2 to 7 of admission) cohort based on tocilizumab initiation. The primary outcome was 90 day all-cause mortality, in early versus late cohorts. Secondary outcomes were 28 and 180 day all-cause mortality.
Results
203 patients were included (138 in the early cohort and 65 in the late cohort). Mortality was significantly higher in the late cohort compared to the early cohort (adjusted OR: 3.33; CI: 1.29 to 8.54; p = 0.012). The secondary outcomes demonstrated the same effect with higher rates of death at 28 days (late cohort adjusted OR: 3.28; CI 1.23 to 8.75; p = 0.018) and 180 days (late cohort adjusted OR: 3.70; CI 1.45–9.45; p = 0.006). This effect was seen whether the outcome was adjusted or unadjusted. Mortality at 90 days in the early cohort was 22% (n = 30) compared to 45% (n = 29) in the late cohort (P = < 0.001).
Conclusion
Early administration of tocilizumab within the first 2 days of hospitalisation was associated with significant survival benefit compared to late exposure. Late administration was associated with particularly high mortality.
An empirical study on the impact of pre-processing steps for code-mix text
Authors: Tiwari Paras , Chowdary C. Ravindranath 
Published: November 2023

Abstract
Code-mix is widespread in domains like sentiment classification, polarity identification, dialect identification, question answering, part-of-speech tagging, named entity recognition, speech technologies, and other emerging domains. Studying the impact of pre-processing steps has been limited to the monolinguals. The emerging contributions in various applications for code-mix data lack such a dedicated study. Our study fills the gap. In this paper, we conduct an empirical study involving 512 combinations of pre-processing steps with 7 different tokenizers applied to 3 multi-domain datasets. We have investigated the impact of these pre-processing steps and tokenizers on the performance of three conventional neural networks and five machine-learning techniques. Our study includes a detailed analysis of 3,44,064 scores. Our study shows mean differences of 0.3276, 0.2178, 0.1999, and 0.1467 over the Matthews Correlation Coefficient, Macro-F1, Weighted-F1, and Accuracy, respectively , due to the choice of pre-processing steps. We propose to choose the best-performing set of pre-processing steps for good performance.
CKD-Associated Pruritus is associated with greater use of antidepressants and anti-pruritus medications
Authors: Titapiccolo Jasmine Ion , Neri Luca , Schaufler Thilo , Arens Hans-Jurgen , Usvyat Len , Stuard Stefano , Soro Marco 
Published: November 2023

Abstract
Chronic kidney disease–associated pruritus (CKD-aP) is a common, yet underdiagnosed condition among patients on hemodialysis. Considering the lack of established treatment pathways, we sought to evaluate the use of antidepressant, systemic antihistamines or gabapentinoid medications among patients with CKD-aP in the year following pruritus assessment. We included 6209 hemodialysis patients in the analysis. We retrospectivelly extracted clinical and patient-reported data from electronic health records. The intensity of CKD-aP was assessed by KDQOL-36 and 5-D Itch questionnaires. Prescription of antidepressant, antihistamine, and gabapentinoids was ascertained by the occurrence of a suggestive active medical order in patients’ medical records. We observed a consistent and graded association between the severity of CKD-aP and the use of antidepressant, systemic antihistamines and gabapentinoid medications. This association remained consistent and intensified over the duration of the year after pruritus screening. This trend was robust even after accounting for potential confounding factors. Even though we cannot exclude the possibility that these drugs have been prescribed to treat medical conditions warranting their use, previous evidence suggested that doctors may also use such medications in the attempt to buffer CKD-aP. These findings underline the importance of further elucidating current treatment strategies adopted in clinical practice to address CKD-aP.
Fast Dynamical Analysis of High-dimensional Fractional-Order Memristive-Coupled Hopffeld Neural Networks utilizing a modiffed Non-Classical Methods
Authors: Liu Tian Ming , Chen Yan Mao , Liu Qi Xian 
Published: November 2023

Abstract
Solving high-dimensional fractional differential equations has consistently remained one of the most signiffcant challenges within the realm of fractional calculus. Classical numerical methods often grapple with extensive history datasets, resulting in decreased computational efffciency. Existing non-classical methods frequently result in huge dimensional integer-order systems. To address these issues, an improved non-classical method is established in this paper. By introducing an integral interval decomposition strategy, the decay rate of the integrand in the non-classical method is signiffcantly accelerated, achieving a transition from algebraic decay to exponential decay. Consequently, there is a substantial reduction in the dimensionality of the approximate integerorder systems. Simultaneously, the introduction of the interpolation quadrature method further improves the computational accuracy. Theoretical analysis and numerical examples demonstrate that the proposed method offers substantial performance advantages in tackling fractional differential equations. In conclusion, the dynamic behavior of a high-dimensional memristive-coupled Hopffeld neural network was effectively investigated using the proposed method by phase diagrams and bifurcation diagrams. The proposed method demonstrates the capability to accurately identify both chaotic and periodic behavior within the system. Furthermore, it offers a substantial reduction in computation time for high-dimensional systems. This efffciency in capturing complex dynamics while decreasing computational overhead can be highly advantageous in various applications. It holds crucial theoretical implications for the numerical solution of fractional differential equation. Furthermore, it has the potential to foster and stimulate research and practical applications within the realm of fractional order systems.
Internet-assisted cognitive behavioral intervention with telephone coaching versus an educational control for antenatal depression: protocol for a randomized controlled trial with population-based screening
Authors: Sourander Andre , Matinolli Hanna-Maria , Korpilahti-Leino Tarja , Ristkari Terja , Koffert Tarja , Arrhenius Bianca , Ståhlberg Tiia , Hinkka-Yli-Salomäki Susanna , Berglund Mari , Upadhyaya Subina , Yunus Wan Mohd Azam Wan Mohd , Sinokki Atte , Marjamäki Altti , Kankaanranta Iida , Palmroth Johanna , Sourander Saana , Zadkova Anna , Casagrande Linda , Yamada Yuko , Karjalainen Satu , Kurki Marjo , Vuori Miika 
Published: November 2023

Abstract
Background
Antenatal depression is common and identifying effective treatments is crucial to avoid harmful consequences of unrecognized and untreated depression. Up to 15% of pregnant women suffer from antenatal depression and there is mounting evidence that the consequences can be devastating for both the woman and her child.
Methods
This ongoing research project evaluates the efficacy of the Stronger Together internet-assisted cognitive behavioral intervention (iCBT) with telephone coaching for antenatal depression. It is a large population-based two-parallel group randomized controlled trial. The overarching hypothesis is that iCBT programs are easy to access, affordable and will reduce self-reported symptoms of antenatal depression better than an educational control. The intervention group is also expected to report less anxiety symptoms after treatment than the control group.
The study population consists of all Finnish or Swedish speaking women, aged ≥ 18 years, who attend maternity health check-ups at 13-18 weeks of gestation in selected areas of Finland. The aim is to recruit all women who exceed 10 points on the Edinburgh Postnatal Depression Scale and meet other eligibility criteria. Other measures used are the Beck Depression Inventory-II, the General Anxiety Disorder 7-Item Scale, the Pregnancy-Related Anxiety Questionnaire-Revised, the Social Phobia Inventory and the Perceived Stress Scale. The primary data are collected at baseline and 11 weeks after randomization. The women are randomized 1:1 to the Stronger TogetheriCBT intervention, which combines seven weekly themes on a digital platform with weekly telephone coaching, or the educational control group. The CBT components include psychoeducation, behavioral activation, coping with social relationships, cognitive restructuring and preventing setbacks. The educational control group receives psychoeducational material about wellbeing during pregnancy. Both groups continue to receive standard treatment and maternity health check-ups.
Discussion
We hypothesize that the Stronger Together iCBT intervention will reduce self-rated symptoms of antenatal depression, general and pregnancy-related anxiety, social phobia and stress. The intervention might offer an accessible and effective treatment for depressed pregnant women.
Trial registration: ClinicalTrials.gov ID NCT04223115, Date of first registration: January 10, 2020
Advanced OFDM-Based Wideband Transmission and Direction- Finding for Wearable Devices in Rician Channels
Authors: Aldelemy Ahmad , Oguntala George , Gadhafi Rida , Amar Ahmed , Shuaieb Wafa S. , Abd-Alhameed Raed 
Published: November 2023

Abstract
This paper proposes a new technique for wideband transmission and direction-finding using orthogonal frequency division multiplexing (OFDM) for wearable devices in noisy Rician channels. The technique uses a coded OFDM signal combined with a pseudo-random permutation and a Walsh sequence to mitigate inter-carrier interference, peak-to-average power ratio, and frequency offset. The technique also inserts a pilot symbol into each OFDM block and uses it for frequency offset estimation, channel estimation, message detection, and angle of arrival estimation. The technique employs a delay discrimination algorithm to extract the first arriving impulse from each antenna channel and then applies a direction-finding algorithm to estimate the angle of arrival. The technique is evaluated through rigorous simulations using MATLAB. It shows superior performance and reliability compared to existing methods in terms of signal-to-noise ratio, bit error rate, and angle error.
A decadal Twin Dipole mode in the Southern Atlantic and Indian Oceans
Authors: Gao Xing , Li Yuanlong , Lin Pengfei , Zhang Lei , Lu Ying , Ren Qiuping , Wang Fan 
Published: November 2023

Abstract
Our analysis of observed sea surface temperature (SST) data robustly detects dipole-pattern decadal anomalies in the southern Atlantic and Indian Oceans (SAIOs) which co-occur like twins. This trans-basin mode on decadal timescales, termed as the Atlantic-Indian Twin Dipoles (AITDs), is effective in promoting synchronized regional SST extremes in both basins such as the Benguela Niño/Niña and Ningaloo Niño/Niña and thereby exerts notable climatic and socioeconomic impacts. Further, the mechanism of the AITDs is investigated using observational data, ocean model experiments, and climate models. A positive phase of the AITDs – with warm and cold SSTs in the southwestern and northeastern sectors of the SAIOs, respectively – is coupled with alterations in subtropical highs that involve a variety of regional air-sea processes. Specifically, wind-driven coastal ocean dynamics and cloud-controlled radiative heating play key roles in the South Atlantic, while the perturbed turbulent heat flux by air temperature advection is more important in the Indian Ocean. Both the Interdecadal Pacific Oscillation (IPO) and the Southern Annular Mode (SAM) are conducive to the AITDs by modulating the subtropical highs. By highlighting the trans-basin linkage between the SAIOs, our results have important implications for the decadal prediction of the Southern-Hemisphere climate and regional extremes.
Whole exome sequencing shows novel COL4A3 and COL4A4 variants as causes of Alport syndrome in Rio Grande do Norte, Brazil
Authors: Araújo Washington Candeia , Falcão Raul Maia , Uchoa Raquel Araujo Costa , Garcia Carlos Alexandre , Silva Arthur Quintiliano Bezerra , Ferreira Leonardo Capistrano , Duggal Priya , Souza Jorge Estefano S. , Jeronimo Selma M. B. 
Published: November 2023

Abstract
Background. Alport syndrome is a progressive and hereditary nephropathy characterized by hematuria and proteinuria as well as extra renal manifestations as hearing loss and eye abnormalities. The disease can be expressed as autosomal recessive or autosomal dominant at COL4A3 and COL4A4 loci, respectively, or X-linked at the COL4A5 locus. This study investigated two unrelated families with nephropathy from Brazil with the aim to identify the mutations involved with the disease.
Methods. Whole Exome Sequencing was performed for 4 people from each pedigree (case, parents and a sibling). DNA sequences were mapped against the human genome (GRCh38/hg38 build) to identify associated mutations.
Results. Two novel deleterious variants in COL4A3 and COL4A4 loci on chromosome 2 were identified. The variants were detected in the probands with mutant alleles in the homozygous state, a premature stop codon at position 481 of COL4A3 protein and a frameshift mutation leading to a stop codon at position 786 of COL4A4 protein. For both Alport cases the putative variants were surrounded by broad Runs of Homozygosity as well as genes associated with other hereditary nephropathies.
Conclusions. Two novel variants were identified in two unrelated families from northeast of Brazil. The two deleterious variants identified are located on ROH´s locus with all variants in a homozygous state.
Universities driving innovation in the ‘new normal’: a multi-ontological perspective of dynamic capability microfoundations for knowledge exchange
Authors: Kelleher Leonard , Ulrichsen Tomas Coates 
Published: November 2023

Abstract
Governments are calling upon universities to work with civil society, the public and private sectors to harness lessons from the Covid-19 pandemic for a step-change in innovation, to boost economic growth and sustainable/equitable transitions. However, a paucity of university strategic management frameworks which enable enhanced fulfilment of economic development, civic engagement and sustainability social responsibilities through knowledge exchange may impede delivery of this ambition. In this study, we develop a multi-ontological perspective of the dynamic capability microfoundations UK universities are using to enable knowledge exchange and achieve the innovation step-change ambition within the uncertain and dynamic post-pandemic ‘new normal’. We argue that the microfoundations being utilised suggest a reflexivity failure, impeding universities’ ability to adapt their strategic management to foster radical system change, limiting prospects that the step-change ambition will be achieved.
JEL Classification I23 · O30
conceito de violência numa perspectiva decolonial e o modelo discursivo de democracia
Authors: Feldhaus Charles 
Published: November 2023

Este estudo pretende reconstruir alguns traços gerais da concepção de feminismo decolonial de Françoise Vergès na obra Feminismo decolonial e na obra Uma teoria feminista da violência buscando enfatizar de que maneira a teoria discursiva de Jurgen Habermas em sua obra Facticidade e validade enfrenta a questão das demandas sociais por igualdade entre homens e mulheres ao tratar da dialética entre igualdade de direito e igualdade fato no mercado de trabalho. Vergès sustenta que é necessário um tipo de reconstrução da história do feminismo em que o protagonismo das mulheres racializadas seja levado em consideração e que se preste atenção à maneira como o feminismo decolonial e o que ela chama de feminismo civilizatório conceituam a emancipação da mulher. Embora seja importante reconhecer que a inclusão das mulheres racializadas na arena pública ou na esfera pública possa ser ainda insuficiente como uma estratégia para garantir a igualdade das mulheres, a invisibilização das mulheres racializadas pode até mesmo distorcer o ponto do debate da emancipação feminina e Vergès analisa alguns casos para ilustrar seu ponto de vista, como o que se costuma chamar de a polêmica do biquíni na França. Além disso, o próprio conceito de violência numa perspectiva diferenciada do termo, que inclui não apenas a agressão física, mas também a distribuição desigual de tarefas (atividades relacionadas com a manutenção do capital e atividades executivas de empresas) entre mulheres racializadas e mulheres brancas, a distribuição entre as pessoas que podem ser mortas de maneira arbitrária e as que não podem, todos estes aspectos podem ser considerados como um avanço importante na discussão das questões relacionadas com a igualdade na sociedade contemporânea.