bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comorbidity clusters and in-hospital outcomes in patients admitted with acute myocardial infarction in the USA: A national population-based study
Authors: Zghebi Salwa S. , Rutter Martin K. , Sun Louise Y. , Ullah Waqas , Rashid Muhammad , Ashcroft Darren M. , Steinke Douglas T. , Weng Stephen , Kontopantelis Evangelos , Mamas Mamas A. 
Published: October 2023

Background
The prevalence of multimorbidity in patients with acute myocardial infarction (AMI) is increasing. It is unclear whether comorbidities cluster into distinct phenogroups and whether are associated with clinical trajectories.

Methods
Survey-weighted analysis of the United States Nationwide Inpatient Sample (NIS) for patients admitted with a primary diagnosis of AMI in 2018. In-hospital outcomes included mortality, stroke, bleeding, and coronary revascularisation. Latent class analysis of 21 chronic conditions was used to identify comorbidity classes. Multivariable logistic and linear regressions were fitted for associations between comorbidity classes and outcomes.

Results
Among 416,655 AMI admissions included in the analysis, mean (±SD) age was 67 (±13) years, 38% were females, and 76% White ethnicity. Overall, hypertension, coronary heart disease (CHD), dyslipidaemia, and diabetes were common comorbidities, but each of the identified five classes (C) included ≥1 predominant comorbidities defining distinct phenogroups: cancer/coagulopathy/liver disease class (C1); least burdened (C2); CHD/dyslipidaemia (largest/referent group, (C3)); pulmonary/valvular/peripheral vascular disease (C4); diabetes/kidney disease/heart failure class (C5). Odds ratio (95% confidence interval [CI]) for mortality ranged between 2.11 (1.89–2.37) in C2 to 5.57 (4.99–6.21) in C1. For major bleeding, OR for C1 was 4.48 (3.78; 5.31); for acute stroke, ORs ranged between 0.75 (0.60; 0.94) in C2 to 2.76 (2.27; 3.35) in C1; for coronary revascularization, ORs ranged between 0.34 (0.32; 0.36) in C1 to 1.41 (1.30; 1.53) in C4.

Conclusions
We identified distinct comorbidity phenogroups that predicted in-hospital outcomes in patients admitted with AMI. Some conditions overlapped across classes, driven by the high comorbidity burden. Our findings demonstrate the predictive value and potential clinical utility of identifying patients with AMI with specific comorbidity clustering.
Medicine information helpline after hospitalization–a randomized trial: Impact on patient satisfaction, patient concerns about medicines and clinical outcome on patient safety
Authors: Fjære Karianne Wilhelmsen , Vejborg Tim Emil , Colberg Lene , Ulrich Cecilia Strøjer , Pedersen Lars , Demény Ann Kathrin , Poulsen Joo Hanne , Armandi Helle Byg , Clemmensen Marianne Hald 
Published: October 2023

Background and aim
Hospitalization often leads to changes in patients’ medicine which challenges a safe medication use after discharge. Medicine information helplines (MIHs) can be valuable for patients in overcoming these challenges. This study evaluates patient satisfaction with a newly established Danish hospital-based MIH for discharged patients. The MIH is operated by experienced pharmacists and a pharmacy technician, and the study explores how the service affects the patient’s concerns and perception of safety in relation to their medication, followed by an assessment of the clinical impact of MIH on patient safety.

Method
A randomized controlled study design was used in the present study. The study was registered at clinicaltrials.gov with the identification number NCT03829995. Participants were randomized 1:4 (50:200) into a control- and intervention group. Participants in the control group were offered standard care and those in the intervention group were offered access to the MIH. A telephone interview performed 2–4 weeks after discharge assessed patient satisfaction with the helpline and patient’s feeling of safety in relation to medicine use (primary outcome). Data were analyzed using a Mann-Whitney U test. After case handling of each enquiry to the MIH, the cases were assessed with regard to medication-related problems (MRPs) and clinical impact of the MIH service was assessed (primary outcome).

Results
A total of 250 participants were included in the study and 152 participated in the telephone interviews (33 control and 119 intervention). Thirty-seven questions were enquired by 26 participants to the MIH. Of these, 8 were requested before the telephone interviews and these patients all expressed a high satisfaction with the MIH (score 4.57 +/- 0.73 on a 5-point scale). Most patients offered access to the MIH expressed that it increased the sense of safety in relation to their medicines (79%). However, comparing the control- and intervention group with regard to patient concerns and feeling of safety in relation to medicine use no differences were found. Evaluation of the enquiries revealed at least one MRP per enquiry, and in most cases the advice given were assessed to have a high- or moderate clinical significance.

Conclusion
The MIH was appreciated by the participants, indicating that the MIH could be a valuable service for discharged patients in improving the sense of safety in relation to medication and alleviating MRPs. Providing easy access for patients to medicine information may contribute to patient safe medicine use after discharge.
Narrativas de las miradas: evocación de sentidos y experiencias corporales
Authors: Bohórquez Juliette 
Published: October 2023

Es una reflexión generada a partir de “tomar prestada[1]” la experiencia que tuvieron algunos participantes del Taller Itinerante de Arte para La Paz -TIAP- Medellín con el uso de la cámara subjetiva, buscando un acercamiento que permitiera ver, leer e interpretar los usos del y con el cuerpo en el taller desarraigo. Puntos de vista que generan unas narrativas corporales que tienen correspondencia con el territorio, en tanto el cuerpo mismo es concebido como tal, a la vez que se integra y dispone dentro de este; propiciando correlatos que dan cuenta sobre esas maneras de relacionamiento y descripciones de acciones, sensaciones, emociones y significados, como de memorias manifestadas dentro de ellos; convirtiéndose en otra forma, diferente a la oral, de relatar, en este caso, experiencias de desarraigo.

[1] Término que tomo del artículo “Compartir la mirada desde la cámara subjetiva” de David Romero Duque. En prensa.
Relaxed many-body optimal transport and related asymptotics
Authors: Bindini Ugo , Bouchitté Guy 
Published: October 2023

Abstract
Optimization problems on probability measures in

ℝ
d

{\mathbb{R}^{d}}

are considered where
the cost functional involves multi-marginal optimal transport. In a model of N interacting particles,
for example in Density Functional Theory, the interaction cost is repulsive and described by a two-point function

c
⁢

(
x
,
y
)

=

ℓ
⁢

(

|

x
-
y

|

)

{c(x,y)=\ell(\lvert x-y\rvert)}

where

ℓ
:

ℝ
+

→

[
0
,
∞
]

{\ell:\mathbb{R}_{+}\to[0,\infty]}

is decreasing to zero at infinity.
Due to a possible loss of mass at infinity, non-existence may occur and relaxing the initial problem over sub-probabilities becomes necessary.
In this paper, we characterize the relaxed functional generalizing the results of [4] and
present a duality method which allows to compute the Γ-limit as

N
→
∞

{N\to\infty}

under very general assumptions on the cost

ℓ
⁢

(
r
)

{\ell(r)}

. We show that this limit coincides with the convex hull of the so-called direct energy. Then we study the limit optimization problem when a continuous external potential is applied. Conditions are given with explicit examples under which minimizers are probabilities or have a mass

<
1

{<1}

.
In a last part, we study the case of a small range interaction

ℓ
N

⁢

(
r
)

=

ℓ
⁢

(

r
/
ε

)

{\ell_{N}(r)=\ell(r/\varepsilon)}

(

ε
≪
1

{\varepsilon\ll 1}

) and we show how the duality approach can also be used to determine the limit energy as

ε
→
0

{\varepsilon\to 0}

of a very large number

N
ε

{N_{\varepsilon}}

of particles.
Existence of non-negative periodic solutions for a degenerate anisotropic parabolic equation with strongly nonlinear source
Authors: Jourhmane Hamza , Kassidi Abderrezak , Elomari M’hamed , Hilal Khalid 
Published: October 2023

Abstract
The purpose of the present work is investigating a degenerate parabolic equation with anisotropic p-Laplacian operator and strongly nonlinear source under boundary conditions of Dirichlet type;
the existence of a periodic non-negative solution is shown. The proof is based on the Leray–Schauder topological degree, which is tricky to work with in this kind of equations.
Naringin ameliorates 5-fluorouracil elicited neurotoxicity by curtailing oxidative stress and iNOS/NF-ĸB/caspase-3 pathway
Authors: Zhou Peili , Wang Zhongfang , Chen Cheng , Famurewa Ademola C. , Olatunji Opeyemi Joshua 
Published: October 2023

Abstract
This study evaluated the protective effects of naringin (NRG) against 5-fluorouracil (5-FU)-elicited neurotoxicity. The animals were orally administered with NRG and subsequently injected with 5-FU. Injection of 5-FU caused depression in cerebral antioxidant enzymes, including glutathione peroxidase, superoxide dismutase, catalase, reduced glutathione and total protein levels, whereas malondialdehyde and acetylcholinesterase levels/activities were considerably upregulated. In addition, 5-FU-triggered cerebral pro-inflammation was shown via significantly increased levels of pro-inflammatory cytokines, inducible nitric oxide synthase, nuclear factor-ĸB, and caspase-3. Furthermore, necrotic and inflammatory histopathological lesions were observed in the cerebral tissues. Interestingly, the NRG administration considerably inhibited 5-FU-instigated cerebral oxido-inflammatory and apoptotic parameters in the treated animals. Thus, NRG could mitigate the neurotoxicity of 5-FU via the inhibition of oxido-inflammation and apoptosis in rats. These results suggested that NRG may have a relevant therapeutic importance in the management of 5-FU-elicited neurotoxicity.
Graphical solutions to one-phase free boundary problems
Authors: Engelstein Max , Fernández-Real Xavier , Yu Hui 
Published: October 2023

Abstract
We study viscosity solutions to the classical one-phase problem and its thin counterpart. In low dimensions, we show that when the free boundary is the graph of a continuous function, the solution is the half-plane solution. This answers, in the salient dimensions, a one-phase free boundary analogue of Bernstein’s problem for minimal surfaces.
As an application, we also classify monotone solutions of semilinear equations with a bump-type nonlinearity.
Impact of waste materials (glass powder and silica fume) on features of high-strength concrete
Authors: Saify Samir , Radhi Mohammed Sattar , Al-Mashhadi Samer A. , Mareai Basim , Jabr Sarah Fadel , Mohammed Zainab Adel , Al-Khafaji Zainab , Al-Husseinawi Fatimah 
Published: October 2023

Abstract
Pozzolanic materials, glass powder, and silica fume (SF) have all been used in concrete recently as a partial cement substitution to increase the strength of the concrete. The aim of this study is to analyze the impact of waste glass powder (WGP) and SF combination on high-strength concrete (HSC) characteristics. The working methodology of the current research consists of using SF passed through sieve No. 200, and WGP particles that passed through sieve No. 400 (particle size less than 38 µm), maximum size of aggregate (14, 20) mm and W/C + p (0.25, 0.35, and 0.45). The used waste materials were in three different amounts of SF and WGP (5, 10, and 15%) by weight of cement. HSC was tested for compressive strength, density, and ultrasonic pulse velocity (UPV) with various glass powder and SF contents. The obtained results show that after 7 and 28 days, concrete specimens containing 15% glass powder and SF demonstrated an increase in density, UPV, and compressive strength, depending on the test results. Conversely, concrete specimens with 5% SF and WGP had decreased compressive strength, UPV, and density. It was detected that WGP gave high mechanical (compressive strength) and physical properties (density and UPV) than SF with a ratio of 15% and lower properties with a ratio of 5%. In HSC manufacturing, glass powder may be used instead of SF.
Open orbits and primitive zero ideals for solvable Lie algebras
Authors: Baklouti Ali , Ishi Hideyuki 
Published: October 2023

Abstract
The aim of the paper is to provide a characterization criterion of exponential solvable Frobenius Lie algebras (having open coadjoint orbits), in terms of primitive ideals of the associated enveloping algebra.
In the case of complex solvable Lie algebras, we also show that an algebraic adjoint orbit is open if and only if the associated primitive ideal through the Dixmier map is trivial.
Electrostatic system with divergence-free Bach tensor and non-null cosmological constant
Authors: Leandro Benedito , Lousa Róbson 
Published: October 2023

Abstract
We prove that three-dimensional electrostatic manifolds with divergence-free Bach tensor are locally conformally flat, provided that the electric field and the gradient of the lapse function are linearly dependent. Consequently, a three-dimensional electrostatic manifold admits a local warped product structure with a one-dimensional base and a constant curvature surface fiber.
Concentrating solutions for singularly perturbed fractional (N/s)-Laplacian equations with nonlocal reaction
Authors: Yuan Shuai , Rădulescu Vicenţiu D. , Tang Xianhua , Zhang Limin 
Published: October 2023

Abstract
This paper is concerned with the following fractional (N/s)-Laplacian Choquard equation:

ε
N

⁢

(

-
Δ

)

N
/
s

s

⁢
u

+

V
⁢

(
x
)

⁢

|
u
|

N
s

-
2

⁢
u

=

ε
μ

⁢

(

1

|
x
|

N
-
μ

∗
F

⁢

(
u
)

)

⁢
f
⁢

(
u
)

,

x
∈

ℝ
N

,

\varepsilon^{N}(-\Delta)_{N/s}^{s}u+V(x)\lvert u\rvert^{\frac{N}{s}-2}u=%
\varepsilon^{\mu}\Bigl{(}\frac{1}{\lvert x\rvert^{N-\mu}}\ast F(u)\Bigr{)}f(u)%
,\quad x\in{\mathbb{R}}^{N},

where

(

-
Δ

)

N
/
s

s

{(-\Delta)_{N/s}^{s}}

denotes the (N/s)-Laplacian operator,

0
<
μ
<
N

{0<\mu<N}

, and V and f are continuous real functions satisfying some mild assumptions. Applying the weak growth conditions on the exponential critical nonlinearity f and without using the strictly monotone condition, we use some refined analysis and develop the arguments in the existing results to establish the existence of the ground state solution of the fractional (N/s)-Laplacian Choquard equation. Moreover, we also study the concentration phenomenon of the ground state solutions.
As far as we know, our results seem to be new concerning the fractional (N/s)-Laplacian equation with the Choquard reaction.
Inverse nodal problem for singular Sturm–Liouville operator on a star graph
Authors: Amirov Rauf , Arslantaş Merve , Durak Sevim 
Published: October 2023

Abstract
In this study, singular Sturm–Liouville operators on a star graph
with edges are investigated. First, the behavior of sufficiently large eigenvalues is
learned. Then the solution of the inverse problem is given to determine the
potential functions and parameters of the boundary condition on the star graph
with the help of a dense set of nodal points. Lastly, a constructive solution to the inverse problems of this class
is obtained.
Developmental scores in offspring of women with subclinical hypothyroidism in pregnancy are affected by gender and thyrotropin cutoff
Authors: Stryhn Julie Kristine Guldberg , Væver Mette Skovgaard , Hoffmann Anne Lisbeth , Gæde Peter Haulund 
Published: October 2023

Abstract

Objectives
Subclinical hypothyroidism (SCH) is defined by elevated thyrotropin (TSH) and normal level of thyroxine (T4). The definition of SCH and the cutoff for TSH normality in pregnancy are debated. In the present study, we assess offspring perinatal outcome, anthropometrics and early development in relation to different TSH levels.

Methods
An observational study with 77 singleton-pregnant women included by thyroid screening before a planned cesarean section. Two TSH-cutoffs (3.0 and 3.7 mIU/L) defined euthyroid and SCH groups, and were applied to evaluate offspring anthropometrics, complication rates (maternal blood loss, Apgar-score, cord arterial-pH, admission to neonatal intensive care unit, perinatal hypoglycemia) and offspring development. Development was evaluated by Bayley-III test in a subsample at age 6 months (n=27) and 15 months (n=22).

Results
Prevalence of SCH was 31.2 % at TSH-cutoff 3.0 mIU/L, and 16.9 % at TSH-cutoff 3.7 mIU/L. No differences in complications and anthropometrics were observed. In Bayley-III tests, cognitive score was decreased at 6 months (p=0.012) and at 15 months (p=0.056) by applying TSH-cutoff 3.0 mIU/L. At cutoff 3.7 mIU/L, motor score was decreased at 15 months (p=0.020). Male offspring had significantly lower cognitive scores at age 6 and 15 months (TSH-cutoff 3.0 mIU/L), and motor scores at age 15 months (TSH-cutoff 3.7 mIU/L).

Conclusions
The importance of the definition of thyroid normality in pregnancy is underlined. This study suggests that a gender-effect might be present in maternal thyroid disease, and that developmental differences exist if TSH-cutoff is low. Further research is needed.
The impact of the COVID-19 pandemic on antenatal care provision and associated mental health, obstetric and neonatal outcomes
Authors: Woods Anousha , Ballard Emma , Kumar Sailesh , Mackle Tracey , Callaway Leonie , Kothari Alka , De Jersey Susan , Bennett Elizabeth , Foxcroft Katie , Willis Meg , Amoako Akwasi , Lehner Christoph 
Published: October 2023

Abstract

Objectives
The COVID-19 pandemic imposed many challenges on pregnant women, including rapid changes to antenatal care aimed at reducing the societal spread of the virus. This study aimed to assess how the pandemic affected perinatal mental health and other pregnancy and neonatal outcomes in a tertiary unit in Queensland, Australia.

Methods
This was a retrospective cohort study of pregnant women booked for care between March 2019 – June 2019 and March 2020 – June 2020. A total of 1984 women were included with no confirmed cases of COVID-19. The primary outcome of this study was adverse maternal mental health defined as an Edinburgh Postnatal Depression Scale score of ≥13 or an affirmative response to ‘EPDS Question 10’. Secondary outcomes were preterm birth <37 weeks and <32 weeks, mode of birth, low birth weight, malpresentation in labour, hypertensive disease, anaemia, iron/vitamin B12 deficiency, stillbirth and a composite of neonatal morbidity and mortality.

Results
There were no differences in the primary perinatal mental health outcomes. The rates of composite adverse neonatal outcomes (27 vs. 34 %, p<0.001) during the pandemic were higher; however, there was no difference in perinatal mortality (p=1.0), preterm birth (p=0.44) or mode of delivery (p=0.38).

Conclusions
Although there were no adverse consequences on maternal mental health during the pandemic, there was a concerning increase in neonatal morbidity potentially due to the altered model of maternity care implemented in the early COVID-19 pandemic.
THE INTERACTION BETWEEN ANCIENT MONGOLIAN NOMADS AND OTHER CIVILIZATIONS OF THE WORLD
Authors: Namjil Т. , Serchmaa Sh. 
Published: October 2023

Summary
In modern-day, the overall trend of international development is that the countries of the world become closer and more interdependent than ever before. In recent years, there has been a growing effort to join forces and address common challenges on their continents, and the world along with countries have become more interconnected and interdependent. In this article, we will try to explain the historical image and connections and interactions of the development of nomadic civilizations as widely as possible, i.e., in the context of the world, and compare them with Mongolia in terms of logical connections.
Assessment of noise pollution and associated subjective health complaints in Jharia Coalfield, India: A structural equation model analysis
Authors: Tiwari Shashi Kant , Kumaraswamidhas Lakshmi Annamalai , Garg Naveen 
Published: October 2023

AbstractNoise pollution in the mining industry has become a serious concern in recent years and has aroused extensive health complaints for the mine workers. Despite the increasing knowledge of the association between noise exposure and health effects, only a few studies have investigated the adverse health effects due to noise pollution in the mining industry. The present study aims to determine the interrelationship of mining noise (MN), demographic characteristics (DC), noise sensitivity and noise annoyance (NA) with subjective health complaints (SHC). A PLS-SEM approach has been used to assess the direct and indirect relationship between the influencing factors on the SHC of 272 people in the mines. Field measurements were made using a sound level meter to evaluate the ambient noise levels for 1 h duration during day and night hour shifts in Dhansar and Bastacolla mining areas of the Jharia coalfield. The noise maps revealed that most of the locations have noise levels higher than 70 dB(A). The statistical model suggests that NA is the most important predictor of SHC. Besides, DC and MN induce only indirect effect on SHC. The study shall facilitate in developing a decision support tool for the assessment of noise levels, induced annoyance, SHC, and suitable policy interventions for controlling noise exposure among mine workers in the coalfield.
A facile method to synthesize nZVI-doped polypyrrole-based carbon nanotube for Ag(i) removal
Authors: Zhang Wen-Juan , Ding Ye-Zhi , Wang Ya-Xian , Wang You-Liang , Fei Yu-Long , Ran Meng-Yu 
Published: October 2023

Abstract
The pollution of silver ion (Ag(i)) has become a serious environmental threat and hazard to ecosystem and human health. Thus, the nanoscale zero valent iron (nZVI)-doped polypyrrole-based carbon nanotube (nZVI/CNT) composites were synthesized by a facile method to remove Ag(i) from wastewater due to the toxicity and scarcity nature of Ag(i). In this process, Fe3+ initiated the self-assembly of polypyrrole tubes in the presence of methyl orange, while it also served as an iron source generated nZVI/CNTs by carbothermal reduction method. The nZVI/CNT composites exhibited a homogeneous tubular structure, and the nZVI formed were uniformly dispersed in the nZVI/CNT composites. The nZVI/CNT composites were used as an adsorbent for the removal of Ag(i) and showed a higher adsorption capacity compared to nZVI and CNTs, with a maximum adsorption capacity of 522.41 mg g−1. Ag(i) was adsorbed on nZVI/CNT composites by ion exchange and chelation, where Ag(i) was reduced to non-toxic Ag due to the redox reaction among pyrrolic-N, nZVI, and Ag(i). The adsorption process of Ag(i) on nZVI/CNT composites was dominated by monolayer adsorption. According to our results, nZVI/CNT composites can be used as economical treatment for wastewater containing Ag(i).