bluuebunny/crossref_metadata_2025_split huggingface dataset:
Escaping Damocles’ Sword: Endogenous Climate Shocks in a Growing Economy
Authors: Brausmann Alexandra , Bretschger Lucas 
Published: February 2024

AbstractWe consider a growing economy which is subject to recurring, random, uninsurable, and potentially large and long-lasting climate shocks leading to destruction of infrastructure, land degradation, collapse of ecosystems or similar loss of productive capacity. The associated damages and the hazard rate are endogenously driven by the stock of greenhouse gases. We highlight the important role of the relative risk aversion and provide analytical solutions for the optimal climate policy, the growth rate and the saving propensity of the economy. We stress the importance of jointly determining these variables, especially if the objective is to formulate meaningful policy prescriptions. If, for example, the growth rate or the saving rate are assumed to be exogenous, and thus independent of the characteristics of climate shocks and economic fundamentals, then future economic developments in the face of climate change and, consequently, the future mitigation efforts will deviate from the optimal paths. In a quantitative assessment we show that with log-utility and under favorable technological and climatic conditions the abatement expenditure represents only 0.5% of output, equivalent to $37 per ton carbon. Under less favorable conditions, coupled with a relative risk aversion which exceeds unity, the abatement propensity increases to 2.9%, equivalent to $212 per ton carbon, and it jumps to a striking 16% in the pessimistic scenario involving severe shocks and low efficiency of abatement technology.
Sex-specific ventral dichromatism and melanization in harlequin toads (Atelopus): a common but overlooked character of unknown function
Authors: Plewnia Amadeus , Lötters Stefan , Gomides Samuel , De Agrò Massimo , Rößler Daniela C. 
Published: February 2024

AbstractHidden colors are a widespread phenomenon in the animal kingdom, particularly in anurans. In some cases, hidden colors are suddenly exposed during defensive displays to startle predators, others seemingly remain hidden—particularly from researchers. Amazonian species of Neotropical harlequin toads (genus Atelopus) show striking and consistent ventral sexual dichromatism where females show and males generally lack melanization. Inspired by these observations we undertook a deeper inquiry across this species-rich genus. We collected data on ventral sexual dichromatism in Atelopus species and scored expression of sex-specific ventral melanization (i.e. black, brown and/or grey coloration). Ventral sexual dichromatism was present throughout the entire range of the genus and in almost all phylogenetic groups. However, there was a clear geographic signal with this trait being most common and widespread in Amazonian Atelopus species. Ventral melanization was correlated with temperature and elevation. Focusing on the Amazonian species, we present hypotheses on potential functions of sexually dimorphic ventral patterns and sex-specific ventral melanization as a baseline to further investigate the dynamics of sexual and natural selection as potential drivers of these traits. Selective pressures on less exposed body parts, such as ventral sides, likely differ considerably from those on dorsal appearance. Given the amount of research on amphibian coloration, it is remarkable how little we know about the evolution, function and underlying mechanisms of ventral appearance. We hope our work will spark more interest in the flip side of amphibians, thereby broadening our understanding of animal coloration.
Spectral Engineering for Optimal Signal Performance in the Microwave SQUID Multiplexer
Authors: Salum J. M. , García Redondo M. E. , Ferreyro L. P. , Bonilla-Neira J. , Müller N. , Geria J. M. , Bonaparte J. , Muscheid T. , Gartmann R. , Fuster A. , Almela A. , Hampel M. R. , Ardila-Perez L. E. , Sander O. , Kempf S. , Platino M. , Weber M. , Etchegoyen A. 
Published: February 2024

AbstractWe describe a technique to optimize the dynamic performance of microwave SQUID multiplexer (µMUX)-based systems. These systems proved to be adequate for reading out multiple cryogenic detectors simultaneously. However, the requirement for denser detector arrays to increase the sensitivity of scientific experiments makes its design a challenge. When modifying the readout power, there is a trade-off between decreasing the signal-to-noise ratio (SNR) and boosting the nonlinearities of the active devices. The latter is characterized by the spurious free dynamic range (SFDR) parameter and manifests as an increment in the intermodulation products and harmonics power. We estimate the optimal spectral location of the SQUID signal containing the detector information for different channels. Through the technique, what we refer to as Spectral Engineering, it is possible to minimize the SNR degradation while maximizing the SFDR of the detector signal, thus, overcoming the trade-off.
A defense of Isaacson’s thesis, or how to make sense of the boundaries of finite mathematics
Authors: Dopico Pablo 
Published: February 2024

AbstractDaniel Isaacson has advanced an epistemic notion of arithmetical truth according to which the latter is the set of truths that we grasp on the basis of our understanding of the structure of natural numbers alone. Isaacson’s thesis is then the claim that Peano Arithmetic (PA) is the theory of finite mathematics, in the sense that it proves all and only arithmetical truths thus understood. In this paper, we raise a challenge for the thesis and show how it can be overcome. We introduce the concept of purity for theories of arithmetic: a theory of arithmetic is pure when it only proves arithmetical truths. Then, we argue that, under Isaacson’s thesis, some PA-provable truths—including transfinite induction claims for infinite ordinals and some consistency statements—are seemingly not arithmetical in Isaacson’s sense, and hence that Isaacson’s thesis might entail the impurity of PA. Nonetheless, we conjecture that the advocate of Isaacson’s thesis can avoid this undesirable consequence: the arithmetical nature, as understood by Isaacson, of all contentious PA-provable statements can be justified. As a case study, we explore how this is done for transfinite induction claims with infinite ordinals below $$\varepsilon _0$$

ε
0

. To this end, we show that the PA-proof of such claims employs exclusively resources from finite mathematics, and that ordinals below $$\varepsilon _0$$

ε
0

are finitary objects despite being infinite.
3-styrylcoumarin scaffold-based derivatives as a new approach for leishmaniasis intervention: biological and molecular modeling studies
Authors: Yepes Andrés F. , Robledo Sara M. , Quintero-Saumeth Jorge , Cardona-Galeano Wilson 
Published: February 2024

AbstractSeven 3-styrylcoumarins were tested for antileishmanial activity against Leishmania (Viannia) panamensis amastigotes. Cytotoxic activity was also evaluated against mammalian U-937 cells. The 3-methoxy-4-hydroxy coumarin derivative 6 was the most active with an IC50 of 40.5 µM, and did not reveal any conspicuous toxicity toward mammalian U-937 cells. Therefore, it may have potential to be considered as candidate for antileishmanial drug development. Further, among several druggable Leishmania targets, molecular docking studies revealed that compound 6 had docking preference by the N-myristoyltransferase (Lp-NMT) of Leishmania panamensis, showing a higher docking score of − 10.1 kcal mol−1 than positive controls and making this protein as a presumably druggable target for this compound. On the other hand, molecular dynamics simulations affirm the docking hypothesis, showing a conformational stability of the 6/Lp-NMT complex throughout 100 ns simulation. Moreover, the molecular mechanics/Poisson–Boltzmann surface area method also support the docking findings, revealing a total free energy of binding of − 47.26 ± 0.08 kcal mol−1, and identifying through energy decomposition analysis that those key aminoacids are contributing strongly to ligand binding. Finally, an optimal pharmacokinetic profile was also estimated for 6. Altogether, coumarin 6 could be addressed as starting point for further pharmacological studies concerning the therapeutic leishmaniasis intervention.
Graphical abstract
Association Between 18F-FDG PET Activity and HER2 Status in Breast Cancer Brain Metastases
Authors: Young Jonathan R. , Ressler Julie A. , Mortimer Joanne E. , Schmolze Daniel , Fitzgibbons Mariko , Chen Bihong T. 
Published: February 2024

Abstract
Purpose
The objective of this study was to evaluate whether uptake on 18F-fluorodeoxyglucose (18F-FDG) PET could help differentiate HER2-positive from HER2-negative breast cancer brain metastases.

Methods
In this retrospective, cross-sectional study of a cohort of 14 histologically proven breast cancer brain metastases, we analyzed both preoperative 18F-FDG PET/CT and HER2 status of the resected/biopsied brain specimens. The maximum standardized uptake values (SUVmax) of the lesions were normalized to contralateral normal white matter and compared using Mann–Whitney U tests.

Results
The study cohort was comprised of 12 women with breast cancer with a mean age of 59 years (range: 43–76 years) with a total of 14 distinct brain metastatic lesions. The SUVmax ratio of HER2-positive breast cancer brain metastases was significantly greater than that of HER2-negative lesions (3.98 vs 1.79, U = 38.00, p = 0.008).

Conclusion
The SUVmax ratio may help to identify the HER2 status of breast cancer brain metastases, if validated prospectively.
Does information about MIH on dental homepages in Germany offer high quality? A systematic search and analysis
Authors: Geiken A. , Banz L. , Kock M. , Schwendicke F. , Graetz C. 
Published: February 2024

Abstract
Purpose
The internet is increasingly used to seek health information. A dental condition of increasing concern and public interest is molar incisor hypomineralisation (MIH), why we evaluated the information quality of German dentists ‘websites on the topic of MIH.

Methods
A systematic search was performed by two independent investigators using three search engines. The information content of websites on MIH and technical, functional aspects, overall quality, and risk of bias were assessed using validated instruments (LIDA, DISCERN). Practice-related characteristics (practice type, specialization, setting, number and mean age of dentists) were recorded, and associations of these characteristics with websites’ overall quality were explored using multivariable linear regression modelling.

Results
70 sites were included. 52% were multipractices in urban areas (49%). The most common age group was middle-aged individuals (41–50 years). The average number of dentists/practice was 2.5. The majority met more than 50% of the DISCERN and LIDA criteria (90%, 91%). The MIH definition was frequently used (67%), MIH symptoms were described (64%), and 58% mentioned therapies. The prevalence of MIH was mentioned less frequently (48%). MIH example photographs were rarely shown (14%). In multivariable analysis, most practice-related factors were not significant for overall site quality. Only chain practices had slightly higher quality in this regard (2.2; 95% CI of 0.3–4.1).

Conclusions
MIH is mentioned on a large proportion of dentists’ websites. Overall technical, functional, and generic quality was high. Risk of bias is limited. While most websites provided a basic definition of MIH and its symptoms, important information for patients was missing.
Spelling and Autism: a Narrative Review of Recent Developments and Directions for New Research Priorities
Authors: Bailey Benjamin , Ray Karen 
Published: February 2024

Abstract
Purpose of Review
This review provides a critical overview of recent research on spelling and autism, highlighting developments and future research priorities.

Recent Findings
It has long been known that some children with autism have difficulty learning to spell. Recent studies have explored the reasons why these children have difficulty learning to spell and how they are best supported to learn to spell.

Summary
Spelling development has been linked to various factors in groups of autistic children, with language skills and intellectual functioning identified as key contributors to spelling achievement. Autistic and non-autistic children appear to draw on similar processes when spelling and may benefit from similar forms of instruction. Additional participatory research guided by autistic children, their parents and teachers is needed to further our understanding of spelling development and efficacious spelling instruction for autistic children. Potential avenues for future research are presented.
Development of Experimental Low-Cost Rain Gauges and their Evaluation During a High Intensity Storm Event
Authors: Dervos Nikolaos A. , Baltas Evangelos A. 
Published: February 2024

AbstractThe measurement of rainfall via ground sensors is fundamental in a variety of hydrological applications, including rainfall-runoff simulations, basin water balance and flood forecasting. The tipping bucket rain gauge (TBR) constitutes the most common type of automatic gauge for the measurement of rainfall intensity. The objective of this work is the development of low-cost and reliable rain gauges, including their data logger, which could be installed at remote, rural areas, in order to supplement with rainfall data the limited or non-existing network of hydrological stations. To achieve this target, two experimental TBRs with diameters of 20 cm (RG20) and 28 cm (RG28) were developed. Electronic boards Arduino UNO and Raspberry Pi were used for their data logger. The measurements of RG20 and RG28 were compared with those of a high quality rain gauge ARG100 and a daily non-recording rain gauge. The cyclone Daniel on 06-09-2023 caused an intermittent storm event in the city of Athens, Greece, which was measured by all three TBRs for purposes of evaluation. The results showed that the variations between ARG100 and RG28 were lower than 6%, while the variations between ARG100 and RG20 were about 10% during a few time intervals of high rainfall intensity. The return period of the storm event were estimated at 43, 59 and 45 years for rainfall durations of 10, 20 and 30 min, respectively.
The search for neutrinoless double-beta decay
Authors: Gómez-Cadenas Juan José , Martín-Albo Justo , Menéndez Javier , Mezzetto Mauro , Monrabal Francesc , Sorel Michel 
Published: February 2024

Abstract
Neutrinos are the only particles in the Standard Model that could be Majorana fermions, that is, completely neutral fermions that are their own antiparticles. The most sensitive known experimental method to verify whether neutrinos are Majorana particles is the search for neutrinoless double-beta decay. The last 2 decades have witnessed the development of a vigorous program of neutrinoless double-beta decay experiments, spanning several isotopes and developing different strategies to handle the backgrounds masking a possible signal. In addition, remarkable progress has been made in the understanding of the nuclear matrix elements of neutrinoless double-beta decay, thus reducing a substantial part of the theoretical uncertainties affecting the particle–physics interpretation of the process. On the other hand, the negative results by several experiments, combined with the hints that the neutrino mass ordering could be normal, may imply very long lifetimes for the neutrinoless double-beta decay process. In this report, we review the main aspects of such process, the recent progress on theoretical ideas and the experimental state of the art. We then consider the experimental challenges to be addressed to increase the sensitivity to detect the process in the likely case that lifetimes are much longer than currently explored, and discuss a selection of the most promising experimental efforts.
Optoelectronic Synapses Based on MXene/Violet Phosphorus van der Waals Heterojunctions for Visual-Olfactory Crossmodal Perception
Authors: Ma Hailong , Fang Huajing , Xie Xinxing , Liu Yanming , Tian He , Chai Yang 
Published: February 2024

AbstractThe crossmodal interaction of different senses, which is an important basis for learning and memory in the human brain, is highly desired to be mimicked at the device level for developing neuromorphic crossmodal perception, but related researches are scarce. Here, we demonstrate an optoelectronic synapse for vision-olfactory crossmodal perception based on MXene/violet phosphorus (VP) van der Waals heterojunctions. Benefiting from the efficient separation and transport of photogenerated carriers facilitated by conductive MXene, the photoelectric responsivity of VP is dramatically enhanced by 7 orders of magnitude, reaching up to 7.7 A W−1. Excited by ultraviolet light, multiple synaptic functions, including excitatory postsynaptic currents, paired-pulse facilitation, short/long-term plasticity and “learning-experience” behavior, were demonstrated with a low power consumption. Furthermore, the proposed optoelectronic synapse exhibits distinct synaptic behaviors in different gas environments, enabling it to simulate the interaction of visual and olfactory information for crossmodal perception. This work demonstrates the great potential of VP in optoelectronics and provides a promising platform for applications such as virtual reality and neurorobotics.
An outbreak of Verticillium dahliae on sycamore maple in a forest stand in Slovenia
Authors: Brglez Ana , Devetak Zina , Ogris Nikica , Radišek Sebastjan , Piškur Barbara 
Published: February 2024

AbstractVerticillium dahliae Kleb., the causal agent of Verticillium wilts, is a devastating plant disease affecting many plant species. Fungus V. dahliae was detected in a partially artificially established Acer pseudoplatanus L. forest stand in central Slovenia. This finding incited further study about the risk of different sources of V. dahliae isolates for maples in forests and the pathogenicity of three V. dahliae isolates of different origins was tested on saplings of A. pseudoplatanus, A. platanoides L., and A. campestre L. The inoculated saplings exhibited disease symptoms, i.e., leaf necrosis and wilting. At the end of the pathogenicity test, typical xylem browning was visible on the cross-sections, and the pathogen was successfully re-isolated. The isolates showed significant differences in their pathogenicity to specific maple hosts, with the agricultural isolate (originated from bell pepper) being the most aggressive on all three maple species. The disease severity index (DSI) and relative area under the disease progress curve (rAUDPC), as well as the success of re-isolation, indicate that A. platanoides is the most susceptible to inoculation with V. dahliae. In addition, significant differences in sapling biomass were observed between treated and control plants. These results suggest that maples in forest stands are threatened by V. dahliae, and biosecurity measures should be considered and implemented in forest management to reduce the transmission and potential spread of the pathogen.
Near-Optimal Feedback Guidance for Low-Thrust Earth Orbit Transfers
Authors: Atmaca D. , Pontani M. 
Published: February 2024

AbstractThis research describes a near-optimal feedback guidance, based on nonlinear orbit control, for low-thrust Earth orbit transfers. Lyapunov stability theory leads to proving that although several equilibria exist, only the desired operational conditions are associated with a stable equilibrium. This ensures quasi-global asymptotic convergence toward the desired final orbit. The dynamical model includes the effect of eclipsing on the available thrust, as well as all the relevant orbit perturbations, such as several harmonics of the geopotential, solar radiation pressure, aerodynamic drag, and gravitational attraction due to the Sun and the Moon. Near-optimality of the feedback guidance comes from careful selection of the control gains. They are identified in two steps. Step (a) is an extensive table search in which the gains are changed in a large interval. Step (b) uses a numerical optimization algorithm that refines the gains found in (a), while minimizing the time of flight. For the numerical simulations, two scenarios are defined: (i) nominal conditions and (ii) nonnominal conditions, which arise from orbit injection errors and stochastic failures of the propulsion system. For case (i), gain optimization leads to obtaining numerical results very close to those corresponding to a known optimal orbit transfer with eclipse arcs. Moreover, for case (ii), extensive Monte Carlo simulations demonstrate that the nonlinear feedback guidance at hand is effective in driving a spacecraft from a low Earth orbit to a geostationary orbit, also in the presence of nonnominal flight conditions.
Modified Playfair for Text File Encryption and Meticulous Decryption with Arbitrary Fillers by Septenary Quadrate Pattern
Authors: Sugirtham N. , Jenny R. Sherine , Thiyaneswaran B. , Kumarganesh S. , Venkatesan C. , Sagayam K. Martin , Dang Lam , Dinh Linh , Dang Hien 
Published: February 2024

AbstractCryptography secures data and serves to ensure the confidentiality of records. Playfair is a cryptographic symmetrical algorithm that encrypts statistics based on key costs. This secret is shared with an authorized person to retrieve data. In the conventional pattern, there is an area complexity and deficiency in letters, numbers, and special characters. This hassle has been overcome in previous studies by editing pattern dimensions. The fillers used throughout the enciphering were not eliminated during the retrieval process, which resulted in the indiscrimination of the retrieved statistics. The proposed method uses a separate quadrate pattern that strengthens the Playfair cipher and guarantees that the fillers are eliminated to ensure the authentic retrieval of records. The fillers indiscriminate and strengthen the set of rules in opposition to brute force and avalanche impact. The proposed algorithm was evaluated with a minimal change in the key, and was found to have an avalanche effect between 65% and 93.7%. The encrypted document is further encoded using the Lempel–Ziv–Markov chain algorithm (LZMA) to provide compressed second-level secured text with a compression ratio of 0.75 for a file size of 100 KB. The pattern was designed to subsidize the integrated characters found on the keyboard.