bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation of artificial intelligence in SMEs: a systematic review of the state of the art and the main implementation challenges
Authors: Oldemeyer Leon , Jede Andreas , Teuteberg Frank 
Published: February 2024

AbstractWhile the topic of artificial intelligence (AI) in multinational enterprises has been receiving attention for some time, small and medium enterprises (SMEs) have recently begun to recognize the potential of this new technology. However, the focus of previous research and AI applications has therefore mostly been on large enterprises. This poses a particular issue, as the vastly different starting conditions of various company sizes, such as data availability, play a central role in the context of AI. For this reason, our systematic literature review, based on the PRISMA protocol, consolidates the state of the art of AI with an explicit focus on SMEs and highlights the perceived challenges regarding implementation in this company size. This allowed us to identify various business activities that have been scarcely considered. Simultaneously, it led to the discovery of a total of 27 different challenges perceived by SMEs in the adoption of AI. This enables SMEs to apply the identified challenges to their own AI projects in advance, preventing the oversight of any potential obstacles or risks. The lack of knowledge, costs, and inadequate infrastructure are perceived as the most common barriers to implementation, addressing social, economic, and technological aspects in particular. This illustrates the need for a wide range of support for SMEs regarding an AI introduction, which covers various subject areas, like funding and advice, and differentiates between company sizes.
Diuretic Treatment in Patients with Heart Failure: Current Evidence and Future Directions—Part II: Combination Therapy
Authors: J.J Cuthbert , J.G.F Cleland , A.L Clark 
Published: February 2024

Abstract
Purpose of Review
Fluid retention or congestion is a major cause of symptoms, poor quality of life, and adverse outcome in patients with heart failure (HF). Despite advances in disease-modifying therapy, the mainstay of treatment for congestion—loop diuretics—has remained largely unchanged for 50 years. In these two articles (part I: loop diuretics and part II: combination therapy), we will review the history of diuretic treatment and current trial evidence for different diuretic strategies and explore potential future directions of research.

Recent Findings
We will assess recent trials, including DOSE, TRANSFORM, ADVOR, CLOROTIC, OSPREY-AHF, and PUSH-AHF, and assess how these may influence current practice and future research.

Summary
There are few data on which to base diuretic therapy in clinical practice. The most robust evidence is for high-dose loop diuretic treatment over low-dose treatment for patients admitted to hospital with HF, yet this is not reflected in guidelines. There is an urgent need for more and better research on different diuretic strategies in patients with HF.
Robust detection of clinically relevant features in single-cell RNA profiles of patient-matched fresh and formalin-fixed paraffin-embedded (FFPE) lung cancer tissue
Authors: Trinks Alexandra , Milek Miha , Beule Dieter , Kluge Julie , Florian Stefan , Sers Christine , Horst David , Morkel Markus , Bischoff Philip 
Published: February 2024

Abstract
Purpose
Single-cell transcriptional profiling reveals cell heterogeneity and clinically relevant traits in intra-operatively collected patient-derived tissue. So far, single-cell studies have been constrained by the requirement for prospectively collected fresh or cryopreserved tissue. This limitation might be overcome by recent technical developments enabling single-cell analysis of FFPE tissue.

Methods
We benchmark single-cell profiles from patient-matched fresh, cryopreserved and archival FFPE cancer tissue.

Results
We find that fresh tissue and FFPE routine blocks can be employed for the robust detection of clinically relevant traits on the single-cell level. Specifically, single-cell maps of fresh patient tissues and corresponding FFPE tissue blocks could be integrated into common low-dimensional representations, and cell subtype clusters showed highly correlated transcriptional strengths of signaling pathway, hallmark, and clinically useful signatures, although expression of single genes varied due to technological differences. FFPE tissue blocks revealed higher cell diversity compared to fresh tissue. In contrast, single-cell profiling of cryopreserved tissue was prone to artifacts in the clinical setting.

Conclusion
Our analysis highlights the potential of single-cell profiling in the analysis of retrospectively and prospectively collected archival pathology cohorts and increases the applicability in translational research.
Natural and engineered xylosyl products from microbial source
Authors: Qi Jianzhao , Kang Shi-jie , Zhao Ling , Gao Jin‑ming , Liu Chengwei 
Published: February 2024

AbstractGlycosylation is a prevalent post-modification found in natural products and has a significant impact on the structural diversity and activity variation of natural products. Glucosylation is the most common type of glycosylation, whereas xylosylation is relatively rare. Despite their unique chemical structures and beneficial activities, xylosylated natural products from microorganisms have received little attention. This review provides, for the first time, a comprehensive summary of 126 microbial-derived xylosylated natural products, including xylosyl-cyathane diterpenes, xylosylated triterpenes, xylosyl aromatic compounds, and others. Among these compounds, xylosyl-cyathane diterpenes represent the highest number of derivatives, followed by xylosylated triterpenes. Xylosyl compounds from bacterial sources have less defined structural profiles compared to those from fungi. The characterization of xylosyltransferase EriJ from Basidiomycota extended the structural diversity of xylosyl cyathane diterpenes. This work provides a valuable reference for the research and use of xylosyltransferase for drug discovery and synthetic chemistry. Further work is needed to explore the potential applications of microbial derived xylosyl compounds and to develop novel xylosyl transferases. With the deepening of genomic sequencing of medicinal fungi, more biosynthesis of bioactive xylosyl compounds is expected to be elucidated in the future.
Graphical Abstract
Ability to Simulate Absorption and Melt Pool Dynamics for Laser Melting of Bare Aluminum Plate: Results and Insights from the 2022 Asynchronous AM-Bench Challenge
Authors: Simonds Brian J. , Tanner Jack , Artusio-Glimpse Alexandra , Parab Niranjan , Zhao Cang , Sun Tao , Williams Paul A. 
Published: February 2024

AbstractThe 2022 Asynchronous AM-Bench challenge was designed to test the ability of simulations to accurately predict laser power absorption as well as various melt pool behaviors (width, depth, and solidification) during laser melting of solid metal during stationary and scanned laser illumination. In this challenge, participants were asked to predict a series of experimental outcomes. Experimental data were obtained from a series of experiments performed at the Advanced Photon Source at Argonne National Laboratories in 2019. These experiments combined integrating sphere radiometry with high-speed X-ray imaging, allowing for the simultaneous recording of absolute laser power absorption and two-dimensional, projected images of the melt pool. All challenge problems were based on experiments using bare aluminum solid metal. Participants were provided with pertinent experimental information like laser power, scan speed, laser spot size, and material composition. Additionally, participants were given absorptance and X-ray imaging data from stationary and scanned laser experiments on solid Ti–6Al–4V that could be used for testing their models before attempting challenge problems. In total, this challenge received 56 submissions from eight different research groups for eight individual challenge problems. The data for this challenge, and associated information, are available for download from the NIST Public Data Repository. This paper summarizes the results from the 2022 Asynchronous AM-Bench challenge as well as discusses the lessons learned to help inform future challenges.
The Marrakesh Treaty to Facilitate Access to Published Works for Persons Who Are Blind, Visually Impaired or Otherwise Print Disabled in the European Union: Reflecting on Its Implementation and Gauging Its Impact from a Disability Perspective
Authors: Ferri Delia 
Published: February 2024

AbstractThe Marrakesh Treaty to Facilitate Access to Published Works for Persons Who Are Blind, Visually Impaired or Otherwise Print Disabled (Marrakesh Treaty) requires State Parties to introduce limitations and exceptions to national copyright rules in order to allow the reproduction, distribution and making available of published works in formats that are accessible to persons who are blind, visually impaired or otherwise print disabled. This Treaty was concluded by the European Union (EU) on behalf of its Member States in 2018. It was then implemented by means of a Directive and a Regulation. On the tenth anniversary of its adoption, and six years after the enactment of the EU implementing acts, this article reflects on the implementation of the Marrakesh Treaty in the EU, highlighting its strengths and shortcomings. It then discusses, from a disability perspective, the impact of the Marrakesh Treaty within Europe on foot of a multimethod empirical study conducted within the projectReCreating Europe. On the whole, this article argues that, in spite of some weaknesses of the Marrakesh Directive, which leaves room for differences across the Member States, the ratification of the Marrakesh Treaty by the EU has supported access to printed materials for people with disabilities.
Territoriality and the Quest for a Unitary Copyright Title
Authors: van Eechoud Mireille M. M. 
Published: February 2024

AbstractAfter 30 years of harmonization at EU level, copyright and related rights remain decidedly territorial in scope. This is despite the continuous quest for an internal market and the profound impact on cross-border creation, dissemination and use of cultural content. This contribution recounts the outcome of research done on territoriality in the context of the ReCreating Europe project. It discusses why national territorial rights persist, what type of legal mechanisms the EU legislature employs to address the adverse effects of territoriality, and sketches a number of models for a unitary title based on Art. 118 TFEU which could be explored going forward.
Lessons From the COVID-19 Unplanned Transition to Online Learning at Home for Students With Disability: Socialisation, Technology, Education and Future Research Opportunities
Authors: Young Kirsty , Clerke Teena 
Published: February 2024

Abstract
Purpose of Review
Periods of transition for children and adolescents with disability are complex but usually anticipated. The COVID-19 pandemic resulted in an unexpected transition to online learning at home for students. This review examines the literature on the transition to online learning at home for students with disabilities in K–12 education during the COVID-19 pandemic and identifies the challenges and perceived benefits that emerged for these students to inform future planned or unplanned transitions to online learning.

Recent Findings
Thirty-one articles met the inclusion criteria. Overall, the transition to online learning generated significant social and technical challenges for students with disability—ranging from inadequate socialisation and engagement issues to technological barriers. There were also notable benefits. For some students, this included fewer social pressures, improvements in mental health and the development of personal skills such as resilience. Parent and caregiver participation in the online learning tasks was crucial, often leading to deeper insights into the learning preferences and needs of students with disability and the ability to tailor and customise learning activities. The review identifies a need for inclusive research methods that actively involve students with disability in research on their online learning experiences. Furthermore, the predominant focus on boys with disability and the lack of representation of specific types of disability and support needs suggest that in future larger studies should strive for a more diverse and representative sample of the students with disability.

Summary
Challenges and benefits reveal much about the disruptive impact the COVID-19 online learning transition exacted on some school-aged students with disability and their families. Greater attention to increasing access to technologies required for online learning is needed. The findings of this review can be applied in the adaptation of existing, or implementation of new learning modalities, accommodations and support for students with disability to promote their inclusion and access to education. Future research should explore a more inclusive approach and identify longer-term impacts of online learning on COVID-19 cohorts of students with disability and identify ways that schools can plan for more effective transition to online learning in the event of a future pandemic or other disaster requiring school closures.
Environmentally adjusted technical efficiency and the impact of energy and transport taxes on the eco-efficiency index of Greek industry
Authors: Bampatsou Christina , Halkos George , Gkampoura Eleni-Christina 
Published: February 2024

AbstractThis study aims to investigate the ecological efficiency of industry in Greece through a sector-wise framework using data envelopment analysis and considering three different types of environmental emissions. Through this quantification, it is possible to determine the degree of internalization of the environmental impact for each sector of the Greek economy. This fact supports the administrative decision-making process for the planning of sustainable industrial development. Subsequently, the effect of energy and transportation taxes on the eco-efficiency index is examined. It is shown that the revenues from the collection of environmental taxes in Greece have not been sufficiently used to improve eco-efficiency. This fact underlines the need to achieve long-term economic development that is compatible with environmental goals and social needs through appropriate strategic decisions and measures. It also highlights the need to create a well-designed tax system in order to reduce environmental pollution and improve environmental quality.
Policy Evolution and Lessons Learned from China’s Efforts to Eliminate Leprosy
Authors: Liu Ying 
Published: February 2024

AbstractThe prevention and treatment of leprosy is a public health and social issue of global concern. China has become the first country in the world to put forward a proposal on the elimination of the harm caused by leprosy. This paper briefly introduces the status of the spread of leprosy in China, and systematically reviews the evolution of policies and measures at different stages of the disease in China, from the serious epidemic of leprosy to the control of the infection, to the basic elimination, and to the elimination of the hazards. On this basis, five main lessons learned from the control and elimination of leprosy in China were also summarized. These provide the basis for promoting the complete global elimination of leprosy and preventing its re-transmission, thereby benefiting all those who still suffer from the scourge of leprosy.
Effectiveness of the continuous professional development training on upper primary mathematics and science and elementary technology teachers’ Pedagogical Content Knowledge in Rwanda
Authors: Nkundabakura Pheneas , Nsengimana Theophile , Uwamariya Eugenie , Nyirahabimana Pascasie , Nkurunziza Jean Baptiste , Mukamwambali Concilie , Dushimimana Jean Claude , Batamuliza Jane , Byukusenge Celine , Iyamuremye Aloys 
Published: February 2024

AbstractThis research aimed to determine the influence of Continuous Professional Development (CPD) training offered by Rwanda Quality Basic education for Capital Human Development Project (RQBEHCD) sub-component 1.2 on upper primary teachers’ Pedagogical Content Knowledge (PCK) in mathematics and science, and elementary technology (SET) subjects. The study adopted an explanatory sequential design to collect and analyze data. Quantitative data were collected from Mathematics and SET achievement tests while qualitative data were collected from semi-structured interview. Quantitative data were collected from 290 participants including 166 male and 124 female teachers. On the other side, the qualitative data were collected from 20 teachers including 12 males and 8 females selected randomly. Descriptive and inferential statistics (repeated measures Analysis of Variance were used to analyze quantitative data while interpretive and thematic analysis were used to analyze qualitative data. The results found high statistical significance in mean scores of mathematics teachers between pre and post-test, with a p < 0.001, medium learning gain of 0.37, and an effect size of 0.450. However, there were no significant differences found between male and female teachers (p > 0.05). Likewise, SET teacher's results showed a significant difference in mean score between pre and post-test with p < 0.01, learning gain of 0.20, and effect size of 0.432 but no significant difference was found between male and female teachers (p > 0.05). In addition, the qualitative results indicated that the CPD program enhanced engagement, interest, confidence, and self-efficacy in teaching Mathematics and Science. Thus, we recommended that the CPD program should be done nationwide to maintain teachers’ PCK in mathematics and science.
The Philosophy of Evolutionary Theory
Authors: Sober Elliott 
Published: February 2024

Natural selection, mutation, and adaptation are well-known and central topics in Darwin's theory of evolution and in the 20th - and 21st -century theories which grew out of it, but many other important topics are used in evolutionary biology that raise interesting philosophical questions. In this book, Elliott Sober analyses a much larger range of topics, including fitness, altruism, common ancestry, chance, taxonomy, phylogenetic inference, operationalism, reductionism, conventionalism, null hypotheses and default reasoning, instrumentalism versus realism, hypothetico-deductivism, essentialism, falsifiability, the principle of parsimony, the principle of the common cause, causality, determinism versus indeterminism, sensitivity to initial conditions, and the knowability of the past. Sober's clear philosophical analyses of these key concepts, arguments, and methods of inference will be valuable for all readers who want to understand evolutionary biology in both its Darwinian and its contemporary forms.
Improving pilots’ tactical decisions in air combat training using the critical decision method
Authors: Mansikka H. , Virtanen K. , Lipponen T. , Harris D. 
Published: February 2024

AbstractIn fighter pilot training, much of upgrade pilots’ (UPs’) learning takes place during mission debriefs. A debrief provides instructor pilots (IPs) the opportunity to correct situation awareness (SA) upon which the UPs base their tactical decisions. Unless the debrief is conducted with proper depth and breadth, the IPs’ feedback on UPs’ SA and tactical decision-making may be incomplete or false, resulting in poor, or even negative learning. In this study, a new debrief protocol based on the Critical Decision Method (CDM) is introduced. The protocol specifically addresses the SA of UPs. An evaluation was conducted to examine if a short CDM training programme to IPs would enhance their ability to provide performance feedback to UPs regarding their SA and tactical decision-making. The IPs were qualified flying instructors and the UPs were air force cadets completing their air combat training with BAe Hawk jet trainer aircraft. The impact of the training intervention was evaluated using Kirkpatrick’s four-level model. The first three levels of evaluation (Reactions, Learning and Behaviour) focused on the IPs, whereas the fourth level (Results) focused on the UPs. The training intervention had a positive impact on the Reactions, Learning and debrief Behaviour of the IPs. In air combat training missions, the UPs whose debriefs were based on the CDM protocol, had superior SA and overall performance compared to a control group.
Brain over brawn: Job polarisation, structural change, and skill prices
Authors: Paweenawat Sasiwimon Warunsiri , Liao Lusi 
Published: February 2024

AbstractThis study investigates the relationship between occupational skills and wages in Thailand using the Labour Force Survey from 1985 to 2020. We quantify the contribution of changes in the skill requirement and highlight the increase in the return on the ‘brain’ and the decrease in the penalty on ‘brawn’, which helps explain the wage distribution changes across periods. We further explore the polarisation in the labour market and analyse the changes in the wage distribution by applying the decomposition method proposed by Firpo et al (2009). Our results suggest that wage dispersion increases in the top end over the first two time periods but decreases in the third time period, while it continues to decrease in the lower end of the distribution.
Emissary to Jews in the Diaspora and to Some Non-Jews, Champion of Jewish Monotheism and Circumspect of Diaspora Judaism: Paul of Tarsus in the Book of Acts
Authors: Stenschke Christoph 
Published: February 2024

AbstractIn Christian tradition, Paul is the apostle to the nations. However, his portrayal in the Book of Acts is more nuanced. For a longer period, Paul's ministry is limited to Jews. Only from Acts 13 onwards does Paul slowly emerge as ministering to non-Jews. Yet even then, Paul remains foremost an emissary to diaspora Judaism. In its apology for Paul and his disputed way of including non-Jews into the people of God, Acts emphasises that Paul did so without diminishing the priority of Israel, as a staunch proponent of Jewish monotheism and in a way that took full account of the precarious situation of diaspora Judaism.
Reading the Gospel of Luke's Walk to Calvary as a Funeral Procession: A Study of Luke 23.27–8
Authors: Closterman Wendy E. 
Published: February 2024

AbstractThis study offers a fresh explanation for the characterisation of the women in Luke 23.27 as mourning. It argues that the uniquely Lukan material of women mourning on the walk to Calvary subtly fashions that walk into a funeral procession. The phrase μὴ κλαίɛτɛ in the following verse, Luke 23.28, recalls accounts of Jesus bringing the dead to life earlier in the Gospel, thereby evoking the concept of resurrection. Luke 23.27-8 works in conjunction with material later in Chapter 23 about the ritual preparation of Jesus’ body, to portray funerary ritual for Jesus conducted in reverse (the funeral procession precedes rather than follows the preparation of the body). This inverted order of funeral allusions adds extra resonance to the endpoint of the Gospel, casting it as the logical culmination of a reverse funeral—the resurrection of Jesus from death to life. The interpretation in this paper highlights one way that lived ritual experiences among the Gospel's readers, in this case, the paradigm of funeral ritual, informed the narrative technique in the Gospel of Luke, complementing other well-recognised uses of Greco-Roman rhetorical devices and literary themes.