bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brain-charting autism and attention deficit hyperactivity disorder reveals distinct and overlapping neurobiology
Authors: Bedford Saashi A. , Lai Meng-Chuan , Lombardo Michael V. , Chakrabarti Bhismadev , Ruigrok Amber , Suckling John , Anagnostou Evdokia , Lerch Jason P. , Taylor Margot , Nicolson Rob , Stelios Georgiades , Crosbie Jennifer , Schachar Russell , Kelley Elizabeth , Jones Jessica , Arnold Paul D. , Courchesne Eric , Pierce Karen , Eyler Lisa T. , Campbell Kathleen , Barnes Cynthia Carter , Seidlitz Jakob , Alexander-Bloch Aaron F. , Bullmore Edward T. , Baron-Cohen Simon , Bethlehem Richard A.I. ,   MRC AIMS Consortium and Lifespan Brain Chart Consortium
Published: December 2023

AbstractBackgroundAutism and attention deficit hyperactivity disorder (ADHD) are heterogeneous neurodevelopmental conditions with complex underlying neurobiology. Despite overlapping presentation and sex-biased prevalence, autism and ADHD are rarely studied together, and sex differences are often overlooked. Normative modelling provides a unified framework for studying age-specific and sex-specific divergences in neurodivergent brain development.MethodsHere we use normative modelling and a large, multi-site neuroimaging dataset to characterise cortical anatomy associated with autism and ADHD, benchmarked against models of typical brain development based on a sample of over 75,000 individuals. We also examined sex and age differences, relationship with autistic traits, and explored the co-occurrence of autism and ADHD (autism+ADHD).ResultsWe observed robust neuroanatomical signatures of both autism and ADHD. Overall, autistic individuals showed greater cortical thickness and volume localised to the superior temporal cortex, whereas individuals with ADHD showed more global effects of cortical thickness increases but lower cortical volume and surface area across much of the cortex. The autism+ADHD group displayed a unique pattern of widespread increases in cortical thickness, and certain decreases in surface area. We also found evidence that sex modulates the neuroanatomy of autism but not ADHD, and an age-by-diagnosis interaction for ADHD only.ConclusionsThese results indicate distinct cortical differences in autism and ADHD that are differentially impacted by age, sex, and potentially unique patterns related to their co-occurrence.
Transposition, duplication, and divergence of the telomerase RNA underlies the evolution ofMimulustelomeres
Authors: Kumawat Surbhi , Martinez Irene , Logeswaran Dhenugen , Chen Hongfei , Coughlan Jenn M. , Chen Julian J.-L. , Yuan Yaowu , Sobel James M. , Choi Jae Young 
Published: December 2023

AbstractTelomeres are nucleoprotein complexes with a crucial role of protecting chromosome ends. It consists of simple repeat sequences and dedicated telomere-binding proteins. Because of its vital functions, components of the telomere, for example its sequence, should be under strong evolutionary constraint. But across all plants, telomere sequences display a range of variation and the evolutionary mechanism driving this diversification is largely unknown. Here, we discovered in Monkeyflower (Mimulus) the telomere sequence is even variable between species. We investigated the basis ofMimulustelomere sequence evolution by studying the long noncoding telomerase RNA (TR), which is a core component of the telomere maintenance complex and determines the telomere sequence. We conducted total RNA-basedde novotranscriptomics from 16Mimulusspecies and analyzed reference genomes from 6 species, and discoveredMimulusspecies have evolved at least three different telomere sequences: (AAACCCT)n, (AAACCCG)n, and (AAACCG)n. Unexpectedly, we discovered several species with TR duplications and the paralogs had functional consequences that could influence telomere evolution. For instance,M. lewisiihad two sequence-divergent TR paralogs and synthesized a telomere with sequence heterogeneity, consisting of AAACCG and AAACCCG repeats. Evolutionary analysis of theM. lewisiiTR paralogs indicated it had arisen from a transposition-mediate duplication process. Further analysis of the TR from multipleMimulusspecies showed the gene had frequently transposed and inserted into new chromosomal positions duringMimulusevolution. From our results, we propose the TR transposition, duplication, and divergence model to explain the evolutionary sequence turnovers inMimulusand potentially all plant telomeres.
Nucleic acid sequence contributes to remodeler-mediated targeting of histone H2A.Z
Authors: Converso Cynthia , Pierrakeas Leonidas , Chan Lirong , Chowdhury Shalvi , Kuznetsov Vyacheslav I. , Denu John M. , Luk Ed 
Published: December 2023

ABSTRACTThe variant histone H2A.Z is inserted into nucleosomes immediately downstream of promoters and is important for transcription. The site-specific deposition of H2A.Z is catalyzed by SWR, a conserved chromatin remodeler with affinity for promoter-proximal nucleosome depleted regions (NDRs) and histone acetylation. By comparing the genomic distribution of H2A.Z in wild-type and SWR-deficient cells, we found that SWR is also responsible for depositing H2A.Z at thousands of non-canonical sites not directly linked to NDRs or histone acetylation. To understand the targeting mechanism of H2A.Z, we presented SWR with a library of nucleosomes isolated from yeast and characterized those preferred by SWR. We found that SWR prefers nucleosomes associated with intergenic over coding regions, especially when polyadenine tracks are present. Insertion of polyadenine sequences into recombinant nucleosomes near the H2A-H2B binding site stimulated the H2A.Z insertion activity of SWR. Therefore, the genome is encoded with information contributing to remodeler-mediated targeting of H2A.Z.
Retroelement-Age Clocks: Epigenetic Age Captured by Human Endogenous Retrovirus and LINE-1 DNA methylation states
Authors: Ndhlovu Lishomwa C. , Bendall Matthew L. , Dwaraka Varun , Pang Alina PS , Dopkins Nicholas , Carreras Natalia , Smith Ryan , Nixon Douglas F. , Corley Michael J. 
Published: December 2023

AbstractHuman endogenous retroviruses (HERVs), the remnants of ancient viral infections embedded within the human genome, and long interspersed nuclear elements 1 (LINE-1), a class of autonomous retrotransposons, are silenced by host epigenetic mechanisms including DNA methylation. The resurrection of particular retroelements has been linked to biological aging. Whether the DNA methylation states of locus specific HERVs and LINEs can be used as a biomarker of chronological age in humans remains unclear. We show that highly predictive epigenetic clocks of chronological age can be constructed from retroelement DNA methylation states in the immune system, across human tissues, and pan-mammalian species. We found retroelement epigenetic clocks were reversed during transient epigenetic reprogramming, accelerated in people living with HIV-1, responsive to antiretroviral therapy, and accurate in estimating long-term culture ages of human brain organoids. Our findings support the hypothesis of epigenetic dysregulation of retroelements as a potential contributor to the biological hallmarks of aging.
Lifelong learner needs for human-centered self-regulated learning analytics
Authors: Nguyen Andy , Lämsä Joni , Dwiarie Adinda , Järvelä Sanna 
Published: December 2023

Purpose
Self-regulated learning (SRL) is crucial for successful learning and lifelong learning in today’s rapidly changing world, yet research has shown that many learners need support for SRL. Recently, learning analytics has offered exciting opportunities for better understanding and supporting SRL. However, substantial endeavors are still needed not only to detect learners’ SRL processes but also to incorporate human values, individual needs and goals into the design and development of self-regulated learning analytics (SRLA). This paper aims to examine the challenges that lifelong learners faced in SRL, their needs and desirable features for SRLA.

Design/methodology/approach
This study triangulated data collected from three groups of educational stakeholders: focus group discussions with lifelong learners (n = 27); five teacher interviews and four expert evaluations. The groups of two or three learners discussed perceived challenges, support needs and willing-to-share data contextualized in each phase of SRL.

Findings
Lifelong learners in professional development programs face challenges in managing their learning time and motivation, and support for time management and motivation can improve their SRL. This paper proposed and evaluated a set of design principles for SRLA.

Originality/value
This paper presents a novel approach for theory-driven participatory design with multistakeholders that involves integrating learners, teachers and experts’ perspectives for designing SRLA. The results of the study will answer the questions of how learners’ voices can be integrated into the design process of SRLA and offer a set the design principles for the future development of SRLA.
Prospects of Islamic capital market in Uzbekistan: issues and challenges
Authors: Asadov Alam , Turaboev Ikhtiyorjon , Yildirim Ramazan 
Published: December 2023

Purpose
Despite its potential as an emerging market for Islamic financial services, Uzbekistan has lagged in legislative support. This study aims to evaluate the feasibility of introducing an Islamic capital market (ICM) in Uzbekistan, preceding a broader industry establishment.

Design/methodology/approach
The authors begin by assessing Islamic finance literacy and the potential demand for ICMs in Uzbekistan. The authors then scrutinize Uzbekistan’s capital market legislation and its readiness. This analysis uses primary data, including surveys and interviews, and secondary data from literature and financial legislation.

Findings
This study highlights a significant demand for ICMs, despite low Islamic finance awareness in Uzbekistan. Presently, Uzbekistan’s capital market development is lacking, with regulations not yet suitable for ICMs. As a result, legal and operational enhancements are needed.

Practical implications
The authors provide essential policy recommendations for authorities and practitioners to facilitate the effective launch of ICMs and enhance Uzbekistan’s capital market stature.

Originality/value
To the best of the authors’ knowledge, this is the first study offering an in-depth analysis of the potential and feasibility of ICMs in Uzbekistan.
Assessing the impact of external determinants on the social performance of Islamic banks
Authors: Meskovic Admir , Avdukic Alija , Kozarevic Emira 
Published: December 2023

Purpose
Explaining the sources of the differences in social performance among Islamic banks (IBs) is the motivation for this research. Consequently, the purpose of this paper is to investigate the relationship between the development of Islamic finance regulation, the development of an Islamic financial system, the proportions of affected Muslim populations and the level of competition, on the one hand, and the social performance of IBs, on the other. To the best of the authors' knowledge, this is the first study that investigates the impact of the development of regulation and the Islamic financial system on the social performance of IBs.

Design/methodology/approach
A balanced panel of annual data for 40 banks from 13 countries is applied, spanning 2012–2018. A social performance index with eight dimensions is constructed and measures the social performance of IBs. The index based on qualitative and quantitative data derives from IBs’ annual reports and financial statements. The linear scaling transformation method articulates the quantitative dimensions of the index. In hypotheses testing, the authors use OLS, LSDV, FEM and Random Effect Model to estimate Model (1) and panel-corrected standard errors with Prais–Winsten transformation to estimate Model (2).

Findings
This unique research confirms the positive impact of the development of Islamic finance regulation on the social performance of IBs. The results show that the development of Islamic finance regulation is consistently significant on all standard significance levels. IBs’ age and the presence of Muslim populations in the country are also significant in most estimators.

Research limitations/implications
The results of this research highlight a significant value for regulators, shareholders and the management of IBs. Without proper regulation, these banks can hardly operate under the principles and expectations of the Islamic moral economy.

Originality/value
This is pioneering research that explores the development of Islamic finance regulation and market concentration as a determinant of social performance of IBs. Development of Islamic finance regulation has proved significant in all estimated models, which confirms that a new variable has been discovered among determinants of the social performance of IBs.
The 2016 US presidential election, opinion polls and the stock market
Authors: Upadhyaya Kamal , Nag Raja , Ejara Demissew 
Published: December 2023

Purpose
The purpose of this paper is to study the impact of the 2016 presidential election polls on the stock market.

Design/methodology/approach
The empirical model includes daily stock returns as the dependent variable and past asset prices, 10-year treasury rates, opinion polls and VIX (market uncertainty) as explanatory variables with a one-year lag. The model was estimated using two sets of daily polling data: from July 1, 2015, to November 8, 2016, and from June 1, 2016, to November 8, 2016. Additional descriptive statistics, such as means and standard deviations, were also calculated.

Findings
The estimated results did not reveal any statistically significant effects of opinion polls in favor of one candidate over another on stock returns. Simple statistical tests, however, show that the market performed better when Trump held a polling advantage over Clinton.

Originality/value
To the best of the authors’ knowledge, this is the only study that has examined the effects of the 2016 presidential election polls on the US stock market. This study adds value to the understanding of the relationship between election polls and the stock market in the USA.
15 years of Airbnb's authenticity that influenced activity participation: a systematic literature review
Authors: Sakr Mohamed Ahmed Qotb , Elsharnouby Mohamed H. , AbdelAziz Gamal Sayed 
Published: December 2023

PurposeThis paper aims to address three research questions (1) Who is the main stakeholder that shapes Airbnb experience, (2) Does Airbnb offers an authentic travel experience? and (3) What should be the future research trends in Airbnb?Design/methodology/approachThis paper uses the systematic literature review (SLR) with a well-defined protocol, research strategy and methods to answer the research questions.FindingsThe review revealed that while Airbnb plays a significant role as the platform provider, the stakeholders influencing the experiences are multifaceted. Hosts, guests, local communities and even regulatory bodies all contribute to shaping the overall Airbnb Experience ecosystem. Hosts, in particular, have a crucial role in curating and delivering unique experiences, which significantly impacts the quality and authenticity of the offerings. On the question of whether Airbnb offers an authentic travel experience, the review uncovered mixed findings. For examples, some studies emphasized the potential for Airbnb to provide authentic and local experiences, allowing travelers to engage with the community and cultural aspects of a destination. However, other studies raised concerns about the commodification and standardization of experiences, leading to a potential loss of authenticity.Originality/valueThis paper is different from previous SLR where previous research systematically reviewed; motivations to use and choose Airbnb, institutionalization of Airbnb, stakeholders of Airbnb. This paper addresses authentic experience as a factor that influences activity participation.
Exploring options to leverage partnership information for designing donation calls
Authors: Nurmala N. , de Vries Jelle , de Leeuw Sander 
Published: December 2023

Purpose
This study aims to help understand individual donors’ preferences over different designs of humanitarian–business partnerships in managing humanitarian operations and to help understand if donors’ preferences align with their actual donation behavior.

Design/methodology/approach
Choice-based conjoint analysis was used to understand donation preferences for partnership designs, and a donation experiment was performed using real money to understand the alignment of donors’ preferences with actual donation behavior.

Findings
The results show that partnering with the business sector can be a valuable asset for humanitarian organizations in attracting individual donors if these partnerships are managed well in terms of partnership strategy, partnership history and partnership report and disclosure. In particular, the study finds that the donation of services and products from businesses corporations to humanitarian organizations are preferable to individual donors, rather than cash. Furthermore, donors’ preferences are not necessarily aligned with actual donation behavior.

Practical implications
The results highlight the importance of presenting objective data on projects to individual donors. The results also show that donors value the provision of services and products by business corporations to humanitarian operations.

Originality/value
Partnerships between humanitarian organizations and business corporations are important for the success of humanitarian operations. However, little is known about which partnership designs are most preferable to individual donors and have the biggest chance of being supported financially.
Services as emulation marketing: conceptualization and concerns
Authors: Lee Christopher , Kahle Lynn 
Published: December 2023

Purpose
The purpose of this paper is to introduce emulation marketing as an important strategy to consider for services marketing researchers and practitioners, given the ability to plant an aspirational goal in consumers' minds. Building on theories of lifestyle, values, self-concept and others, this conceptual paper presents the case for emulation marketing as an important consideration within services marketing.

Design/methodology/approach
To explore mechanisms that will define service research in the future, this conceptual paper reviews the literature across the spectrum of social comparison and learning, social adaptation, conformity, values, persuasion and role modeling. The authors analyze existing theories while proposing a new mechanism, emulation, to advance research in service literature.

Findings
This paper suggests mechanisms to promote emulation in services marketing through the consumer decision process. A research agenda for future work is provided with emphasis on lack of emulation, emulation and status, emulation and aging, emulation and technology, emulation and linguistics and the dark side of emulation. Within each area, a series of considerations are discussed.

Originality/value
This paper introduces emulation as an important mechanism within services marketing. It offers a research agenda focused on a variety of emerging areas in the field. The paper contributes to services marketing and future research by proposing a novel approach, via emulation, to services marketing.
Depth, breadth and structural virality: the influence of emotion, topic, authority and richness on misinformation spread
Authors: Meng Xiao , Dai Chengjun , Zhao Yifei , Zhou Yuan 
Published: December 2023

PurposeThis study aims to investigate the mechanism of the misinformation spread based on the elaboration likelihood model and the effects of four factors – emotion, topic, authority and richness – on the depth, breadth and structural virality of misinformation spread.Design/methodology/approachThe authors collected 2,514 misinformation microblogs and 142,006 reposts from Weibo, used deep learning methods to identify the emotions and topics of misinformation and extracted the structural characteristics of the spreading network using the network analysis method.FindingsResults show that misinformation has a smaller spread size and breadth than true news but has a similar spread depth and structural virality. The differential influence of emotions on the structural characteristics of misinformation propagation was found: sadness can promote the breadth of misinformation spread, anger can promote depth and disgust can promote depth and structural virality. In addition, the international topic, the number of followers, images and videos can significantly and positively influence the misinformation's spread size, depth, breadth and structural virality.Originality/valueThe influencing factors of the structural characteristics of misinformation propagation are clarified, which is helpful for the detection and management of misinformation.
From project to platform: a case study on evolving the software development team
Authors: Coughlin Daniel , Lush Binky 
Published: December 2023

PurposeAt the authors’ libraries, they consolidated two departments and attempted to find ways to increase productivity, reduce duplication and improve job happiness within their software development teams. The authors have lost institutional knowledge when developers leave the team, yet the authors remain responsible for critical library services. The merging of the authors’ departments provided the opportunity to rethink how their teams are structured and whether a different model could provide better professional development, more knowledge sharing and better stability of their services. This article presents a case study of moving from a project-centric approach to a platform-based model.Design/methodology/approachThe authors met with those responsible for establishing priorities for their services and developers to assess successful and unsuccessful implementations and pivoted based on those assessments.FindingsThe authors found that their developers were happier to increase their portfolios and professional development, and the librarians were satisfied with more stable services during a particularly unstable time within the authors’ institution.Originality/valueThis is a practical example of a positive way to structure development teams in libraries. Frequently, teams support a single service to the library because of the criticality of that service on a day-to-day basis, but that can create a lack of shared knowledge during institutional instability. This study reveals the benefits of a platform-based approach, including increased developer happiness, reduced disruptions due to staff turnover and improved system stability. It also discusses the challenges of managing product owners' expectations and balancing feature development with maintenance work.