bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PERPUTARAN MODAL KERJA, STRUKTUR MODAL, DAN PERTUMBUHAN PENJUALAN TERHADAP PROFITABILITAS PADA PERUSAHAAN SUB SEKTOR FARMASI YANG TERDAFTAR DI BURSA EFEK INDONESIA TAHUN 2018-2022
Authors: Anindia Septiani , Amrizal Amrizal 
Published: November 2023

Salah satu sektor industri yang mampu berkembang dan mempertahankan kelangsungan hidup perusahaannya yaitu sektor industri farmasi bahkan sektor ini mampu bertahan dan berkembang dengan pesat ketika terjadi pandemi. Selain itu, sektor ini juga mengalami pertumbuhan laba yang signifikan. Tujuan penelitian ini adalah untuk menguji pengaruh perputaran modal kerja, struktur modal, dan pertumbuhan penjualan baik secara parsial maupun simultan terhadap profitabilitas. Penelitian ini menggunakan desain penelitian kuantitatif asosiatif. Data yang digunakan adalah data sekunder berupa laporan keuangan perusahaan sub sektor farmasi yang terdaftar di Bursa Efek Indonesia tahun 2018-2022. Populasi dalam penelitian ini adalah seluruh Perusahaan Sub Sektor Farmasi yang terdaftar di Bursa Efek Indonesia tahun 2018-2022. Sampel yang digunakan dipilih dengan menggunakan teknik purposive sampling dan diperoleh 7 perusahaan yang memenuhi kriteria. Teknik analisis data menggunakan analisis regresi linear berganda dengan menggunakan alat analisis SPSS Versi 26. Hasil penelitian ini menunjukkan bahwa perputaran modal kerja secara parsial berpengaruh signifikan terhadap profitabilitas, struktur modal secara parsial tidak berpengaruh signifikan terhadap profitabilitas, dan pertumbuhan penjualan secara parsial berpengaruh signifikan terhadap profitabilitas. Hasil pengujian secara simultan menyatakan bahwa perputaran modal kerja, struktur modal, dan pertumbuhan penjualan secara bersama-sama berpengaruh signifikan terhadap profitabilitas.
Kata kunci: Perputaran Modal Kerja, Struktur Modal, Pertumbuhan Penjualan, dan Profitabilitas
Selection of Mungbean Genotypes Against Waterlogging Stress
Authors: Jahan MA , Ahmed F 
Published: November 2023

A pot experiment was conducted in the vinyl house of Sher-e-Bangla Agricultural University (SAU), Dhaka-1207, during kharif-I season (March to June 2022) to identify waterlog tolerant mungbean genotypes. Thirty mungbean genotypes (29 advanced lines and one variety, BARI Mung-6) were evaluated under waterlogging (96 hours) and normal conditions. Waterlogging caused a drastic reduction in dry matter and seed yield in mungbean, however, genotypes showed variable response to waterlogging. Under waterlog condition the higher relative yield was found in M11, M8, M30, M7, M16 and M14 while lower in M2 and M17. Dry matter production also varied among the genotypes due to waterlogging; however, dry matter production of the genotypes M8, M7, M22, M2, M19 and M11 were comparatively higher than other genotypes. Stress tolerance index (STI), yield index (YI) and relative yield (RY) of M16, M20, M7, M8, M11, M30 and M14 were higher than other genotypes. On the basis of dry matter production, STI, YI and RY, genotypes M7, M8, M11, M12, M16, and M20 could be selected as relatively tolerant genotypes against waterlogging stress.
Bangladesh Agron. J. 2023, 26(1): 40-47
Nonligation and ligation of hernial sac technique during orchiopexy for palpable undescended testis in children: A comparative study
Authors: Alam Md Mahbubul , Majumder Partha Sarathy , Adil Syed Abdul , Aziz Md Abdul , Rahman Ashrarur 
Published: November 2023

Purpose: We prospectively evaluated the surgical outcomes of non ligation of hernial sac technique in children with a palpable undescended testis compared with the traditional hernial sac ligation technique during orchiopexy.
Material and Methods: A total of 34 orchiopexies (30 children with age ranged from 6 months to 5 years) were included and randomly assigned to the non ligation of hernial sac technique orchiopexy group (Group-A, 15 children, 16 testes) and the traditional hernial sac ligation orchiopexy group (Group-B, 15 children, 18 testes). Operation time and surgical complications were compared between the two groups. Complications, testicular location and development of inguinal hernia were assessed at the follow-up evaluation for 6 months postoperatively.
Results: The operation time was significantly shorter in Group-A (34.13±10.3 minutes) than Group-B (73.73±28.97 minutes) (<p001). Postoperative complications were found in two cases (wound infection and testicular re-ascent) in Group-B. Wound infection was managed by conservative care and redo surgery was done for testicular re-ascent after 6 months of operation. None of the patients developed post operative inguinal hernia.
Conclusion: We conclude that non ligation of hernial sac technique is a simple procedure that is associated with a shorter operation time than the conventional hernial sac ligation technique during open orchiopexy for palpable undescended testis.
Journal of Paediatric Surgeons of Bangladesh (2016) Vol. 7 (2): 35-40
Comparative Analysis of Anticonvulsant Activity of Trans and Cis 5,5′-Diphenylhydantoin Schiff Bases
Authors: Tchekalarova Jana , Todorov Petar , Stoyanova Tsveta , Atanasova Milena 
Published: November 2023

Recently, the four 5,5′-diphenylhydantoin Schiff bases, possessing different aromatic species (SB1-Ph, SB2-Ph, SB3-Ph and SB4-Ph) were synthesized, characterized, and evaluated for anticonvulsant activity in combination with phenytoin. In the present study, the SB1-Ph and SB4-Ph compounds were selected, based on their anticonvulsant potency, and compared with their cis isomers, prepared after a one-hour exposure to the UV source, for their anticonvulsant potency in the maximal electroshock (MES) test and the kainate (KA)-induced status epilepticus (SE) test in mice. In the MES test, the cis SB1-Ph compound exhibited superior to phenytoin and trans isomer activity in the three tested doses, while the cis SB4-Ph compound entirely suppressed the electroshock-induced seizure spread at the highest dose of 40 mg/kg. Pretreatment with the cis SB1-Ph compound and the cis SB4-Ph at the doses of 40 mg/kg, respectively, for seven days, significantly attenuated the severity of KA SE compared to the matched control group pretreated with a vehicle, while phenytoin was ineffective in this test. The cis SB4-Ph but not the cis SB1-Ph demonstrated an antioxidant effect against the KA-induced SE in the hippocampus. Our results suggest that trans–cis conversion of 5,5′-diphenylhydantoin Schiff bases has potential against seizure spread in the MES test and mitigated the KA-induced SE. The antioxidant potency of cis SB4-Ph might be associated with its efficacy in mitigating the SE.
Antagonistic Activity of Streptomyces alfalfae 11F against Fusarium Wilt of Watermelon and Transcriptome Analysis Provides Insights into the Synthesis of Phenazine-1-Carboxamide
Authors: Dong Dan , Li Maoying , Zhang Taotao , Niu Zhenfeng , Xue Guoping , Bai Hongmei , Zhao Wenyu , Yu Jiajia , Jiang Wei , Wu Huiling 
Published: November 2023

Streptomyces alfalfa strain 11F has inhibitory effects on many phytopathogenic fungi and improves the establishment and biomass yield of switchgrass. However, the antagonistic effects of strain 11F on Fusarium wilt of watermelon and its secondary metabolites that contribute to its biocontrol activity are poorly understood. We evaluated the antagonistic and growth-promoting effects of strain 11F and conducted a transcriptome analysis to identify the metabolites contributing to antifungal activity. Strain 11F had marked inhibitory effects on six fungal pathogens. The incidence of Fusarium wilt of watermelon seedlings was decreased by 46.02%, while watermelon seedling growth was promoted, as indicated by plant height (8.7%), fresh weight (23.1%), and dry weight (60.0%). Clean RNA-sequencing data were annotated with 7553 functional genes. The 2582 differentially expressed genes (DEGs) detected in the Control vs. Case 2 comparison were divided into 42 subcategories of the biological process, cellular component, and molecular function Gene Ontology categories. Seven hundred and forty functional genes (55.47% of the DEGs) were assigned to Kyoto Encyclopedia of Genes and Genomes metabolic pathways, reflecting the complexity of the strain 11F metabolic regulatory system. The expression level of the gene phzF, which encodes an enzyme essential for phenazine-1-carboxylic acid (PCA) synthesis, was downregulated 3.7-fold between the 24 h and 48 h fermentation time points, suggesting that strain 11F can produce phenazine compounds. A phenazine compound from 11F was isolated and identified as phenazine-1-carboxamide (PCN), which contributed to the antagonistic activity against Fusarium oxysporum f. sp. niveum. PCA was speculated to be the synthetic precursor of PCN. The downregulation in phzF expression might be associated with the decrease in PCA accumulation and the increase in PCN synthesis in strain 11F from 24 to 48 h. Streptomyces alfalfae 11F protects watermelon seedlings from Fusarium wilt of watermelon and promotes seedling growth. The transcriptome analysis of strain 11F provides insights into the synthesis of PCN, which has antifungal activity against F. oxysporum f. sp. niveum of watermelon.
Problems of intensification of bank lending to the real sector of the economy in the conditions of martial law
Authors: Dziubliuk Oleksandr 
Published: November 2023

Introduction. The difficult conditions of the economic situation in Ukraine during the period of martial law directly affected the activities of the banking system in terms of credit provision for the production and consumer needs of all market subjects, although problematic moments in the field of bank lending did not arise with the start of full-scale war, but accumulated over a quite long period time. Under such circumstances, the study of the main problems arising in the field of bank lending to the real sector should be considered particularly relevant, so that the functioning of banks in the conditions of martial law is stable and maximally provides the needs of the national economy in terms of credit resources.Purpose. The purpose of the study is to find out the main trends and problems of the organization of bank lending to the economy in the conditions of martial law and, on this basis, determine possible directions for optimizing the credit relations of banks with clients for the effective redistribution of monetary resources in favor of the real sector and contributing to the stabilization of the economic situation in the country.Methods. The methods of the system approach and generalization of data are used to assess trends and regularities in the organization of credit relations. In addition, general scientific and empirical techniques and tools of economic science, methods of analysis and synthesis, comparison, summary and grouping were used.Results. The main trends in the functioning of commercial banks on the credit market and the specific of the formation of the structure of bank assets are studied. Factors affecting the credit activity of the banking system under martial law are systematized. The actions of the National Bank to stimulate the work of the banking sector in lending to the economy are analyzed. The main directions of economic policy, which are necessary as a set of measures for the activation of bank lending to the real sector, are substantiated.Prospects. It is advisable to focus further scientific research on the assessment of the macroeconomic conditions for the effective functioning of the credit mechanism, in particular regarding ensuring the stable value of the national currency, preventing crisis phenomena in the banking system, and reliable legal protection of the interests of banks as creditors.
Pengaruh Lingkungan Kerja dan Pengembangan Karir Terhadap Kinerja Karyawan PT Pelangi Inti Pertiwi Musi Banyuasin
Authors: Romansah Dedi , Yanti Siti Komariah Hilda , Kurniawan Muhammad 
Published: November 2023

Penelitian ini membahas tentang pengaruh lingkungan kerja dan pengembangan karir berpengaruh terhadap kinerja karyawan. Tujuan penelitian ini adalah untuk menganalisis pengaruh lingkungan kerja dan pengembangan karir terhadap kinerja karyawan PT. Pelangi Inti Pertiwi Musi Banyuasin baik secara parsial maupun simultan. Jenis penelitian ini adalah deskriptif kuantitatif. Teknik pengambilan sampel menggunakan metode sensus dengan jumlah sampel sebanyak 93 responden karyawan PT. Pelangi Inti Pertiwi Musi Banyuasin. Uji analisis data mengunakan adalah SPSS versi 25. Hasil penelitian menunjukan bahwa lingkungan kerja berpengaruh positif dan signifikan terhadap kinerja karyawan. Hal ini dapat dilihat pada nilai t hitung sebesar 3.127 dengan signifikansi (0,002 < 0,05). Pengembangan karir berpengaruh positif dan signifikan terhadap kinerja karyawan. Hal ini dapat dilihat pada nilai t hitung sebesar 6.636 dengan signifikansi (0,000 < 0,05). Hasil pengujian yang telah dilakukan mendapatkan nilai F hitung sebesar 40.315>F tabel 2.70 sehingga dapat disimpulkan bahwa lingkungan kerja dan pengembangan karir berpengaruh secara simultan terhadap kinerja karyawan., koefesien determinasi (R2) sebesar 47,30%, sedangkan sisanya 52,70% dipengaruhi oleh variabel lainnya yang belum diteliti.
Úlceras y perforaciones intestinales asociadas a COVID-19
Authors: Perez Karen 
Published: November 2023

La infección por SARS-CoV-2 afecta principalmente el sistema respiratorio, pero se han descrito otros órganos con frecuencia, entre ellos se encuentra el sistema gastrointestinal. Se presenta un caso de una paciente femenina de 35 años de edad con antecedente VIH positivo, quien ingresa a la emergencia por abdomen agudo. Se realiza hemicolectomía derecha, evidenciando multiples perforaciones. Al estudio anatomopatológico se evidencian úlceras, que van de 2.5 x 1.5 a 1 x 1 cm, de bordes irregulares y en estudio de inmunohistoquimica fue positiva para SARS-Cov2. Paciente fallece 3 días después del procedimiento.
D. N. Ushakov was the first… to bring the country to a zugunder!
Authors: Северская О.И. 
Published: November 2023

В статье рассматривается история фразеологизма довести до цугундера от момента его возникновения в армейском жаргоне царской России до наших дней. Автор, используя данные Национального корпуса русского языка, показывает, как переосмысливалось значение опорного элемента цугундер, прослеживая цепочку изменений: ‘сотня палочных ударов’ – ‘наказание, расправа, унижение’ – ‘тюрьма или другое место отбывания наказания’ – ‘любые проблемы’ – ‘ситуация на грани срыва’. Рассматривается и варьирование фразеологизма за счет глагольного компонента, чья лексическая сочетаемость и предопределяет семантический сдвиг.
The article deals with the history of phraseological unit dovesti do tsugundera ‘punish with a hundred stick blows’, from the moment of its origin in the army jargon of tsarist Russia to the present day. The author, using the data of the Russian National Corpus, shows how the meaning of the element zugunder was rethought, tracing the chain of changes: ‘a hundred stick blows’ – ‘punishment, reprisal, humiliation’ – ‘prison or another place of punishment’ – ‘any problems’ – ‘the situation is on the verge of breakdown’. The variation of phraseological unit due to its verbal component, whose lexical compatibility determines the semantic shift, is also considered.
Are Switchback Boundaries Observed by Parker Solar Probe Closed?
Authors: Bizien Nina , Dudok de Wit Thierry , Froment Clara , Velli Marco , Case Anthony W. , Bale Stuart D. , Kasper Justin , Whittlesey Phyllis , MacDowall Robert , Larson Davin 
Published: November 2023

Abstract
Switchbacks are sudden and large deflections in the magnetic field that Parker Solar Probe frequently observes in the inner heliosphere. Their ubiquitous occurrence has prompted numerous studies to determine their nature and origin. Our goal is to describe the boundary of these switchbacks using a series of events detected during the spacecraft’s first encounter with the Sun. Using FIELDS and SWEAP data, we investigate different methods for determining the boundary normal. The observed boundaries are arc-polarized structures with a rotation that is always contained in a plane. Classical minimum variance analysis gives misleading results and overestimates the number of rotational discontinuities. We propose a robust geometric method to identify the nature of these discontinuities, which involves determining whether or not the plane that contains them also includes the origin (
B
= 0). Most boundaries appear to have the same characteristics as tangential discontinuities in the context of switchbacks, with little evidence for having rotational discontinuities. We find no effect of the size of the Parker spiral deviation. Furthermore, the thickness of the boundary is within MHD scales. We conclude that most of the switchback boundaries observed by Parker Solar Probe are likely to be closed, in contrast to previous studies. Our results suggest that their erosion may be much slower than expected.
AC Her: Evidence of the First Polar Circumbinary Planet
Authors: Martin Rebecca G. , Lubow Stephen H. , Vallet David , Anugu Narsireddy , Gies Douglas R. 
Published: November 2023

Abstract
We examine the geometry of the post–asymptotic giant branch (AGB) star binary AC Her and its circumbinary disk. We show that the observations describe a binary orbit that is perpendicular to the disk with an angular momentum vector that is within 9° of the binary eccentricity vector, meaning that the disk is close to a stable polar alignment. The most likely explanation for the very large inner radius of the dust is a planet within the circumbinary disk. This is therefore both the first reported detection of a polar circumbinary disk around a post-AGB binary and the first evidence of a polar circumbinary planet. We consider the dynamical constraints on the circumbinary disk size and mass. The polar circumbinary disk feeds circumstellar disks with gas on orbits that are highly inclined with respect to the binary orbit plane. The resulting circumstellar disk inclination could be anywhere from coplanar to polar depending upon the competition between the mass accretion and binary torques.
Effective Optical Zone and Centration Following SMILE and FS-LASIK for High Myopia Calculated With a Novel Method
Authors: Liu Shengtao , Liu Jingying , Cheng Chiwen , Cai Yu , Huang Yangyi , Han Tian , Xiao Yichen , Zhou Xingtao 
Published: November 2023

Purpose:
To compare the effective optical zone (EOZ) and centration in eyes with high myopia after small incision lenticule extraction (SMILE) and femtosecond laser–assisted in situ keratomileusis (FS-LASIK) using a novel method.

Methods:
Forty eyes of 40 consecutive patients with high myopia scheduled for SMILE or FS-LASIK were enrolled in the study. The EOZ, optical zone decentration, and corneal aberrations were analyzed using Scheimpflug imaging. These values were then analyzed and compared between the two procedures 6 months after surgery.

Results:

The mean EOZ diameter for SMILE (4.41 ± 0.14 mm) was larger than that for FS-LASIK (4.24 ± 0.28 mm;
P
= .002), corresponding to reductions of 1.60 ± 0.11 and 1.71 ± 0.21 mm, respectively, compared with the programmed optical zone (POZ) (
P
= .007). Moreover, the total decentration for SMILE (0.33 ± 0.12 mm) was greater than that for FS-LASIK (0.27 ± 0.15 mm;
P
= .020). The induction of spherical aberration (SA) was lower with SMILE than with FS-LASIK (
P
= .007).

Conclusions:
A larger EOZ and less SA were observed after SMILE than after FS-LASIK in eyes with high myopia.

[
J Refract Surg
. 2023;39(11):736–740.]
CD45.1/CD45.2 Congenic Markers Induce a Selective Bias for CD8+ T Cells during Adoptive Lymphocyte Reconstitution in Lymphocytopenia Mice
Authors: Kalari Kandy Rakhee Rathnam , Fan Xiaoxuan , Cao Xuefang 
Published: November 2023

Abstract
CD45.1/CD45.2 congenic markers have been used to track hematopoietic lineage differentiation following hematopoietic stem and progenitor cell (HSPC) transplantation. However, several studies suggest that a bias exists in CD45.1 versus CD45.2 hematopoietic cell reconstitution from HSPCs. Meanwhile, no definitive comparison has been reported for mature immune cells as to whether the CD45.1/CD45.2 disparity can skew the immune cell response. In this study, using lymphocytopenia Rag1−/− CD45.2 mice as hosts, we assessed the reconstitution potential of CD45.1 versus CD45.2 lymphocytes following adoptive transfer of mature T and B cells. We have found a selective bias for CD8+ T cells in that CD45.1 cells showed significantly higher reconstitution compared with CD45.2 cells, whereas CD4+ T cells and CD19+ B cells showed equivalent reconstitution. These results suggest that CD45.1/CD45.2 markers may induce an alloreactive response or a survival bias specific to CD8+ T cells, and they therefore call for caution for using them as congenic markers in immunologic models.
Rhabdomyolysis-Induced Acute Kidney Injury Treated with Medium Cut-Off Membrane: A Case Report
Authors: Kumthekar Girish V. , Shukla Urvi , Purandare Veena 
Published: November 2023

Abstract
Acute kidney injury can complicate rhabdomyolysis in 10-40% patients. Myoglobinuria and elevated creatine kinase (CK) form the basis of diagnosis. When associated with azotemia and/or oliguria, intermittent hemodialysis is a treatment option. 31-year-old young man came with lower limb pain after doing 800 sit ups. At the presentation, blood pressure was high, serum creatinine was 15.7mg/dl and creatine kinase(CK)>20000 IU/L. Intermittent dialysis was initiated. He developed posterior reversible encephalopathy syndrome, generalized tonic clonic convulsions and a further rise in CK. He underwent extracorporeal removal of myoglobin with medium cut-off (MCO) membrane. After 3 sessions with MCO membrane, myoglobin and CK levels reduced. He was transitioned to conventional dialysis and discharged in a stable condition with complete renal recovery. Medium cut-off membrane effectively removes circulating myoglobin without significant albumin loss and is cost effective.
The Effectiveness of The Six Tier Diagnostic Test (STDT) Instrument in Viewed from Empirical Validity to Identify Student's Misconceptions in Chemical Equilibrium Materials
Authors: Suyono Suyono , Aini Khurrotul , Sanjaya I Gusti Made 
Published: November 2023

Objective: Students are said to understand the concept comprehensively if they master the concepts from dimensions of ontology, epistemology, and axiology. One of the topics that still needs to be clarified is chemical equilibrium. Therefore, it is necessary to develop instruments to diagnose conceptions about the chemical concepts taught. The STDT is one of the instruments that will be developed by researchers, which contains three scientific questions to identify misconceptions in chemical equilibrium. Method: This development research used the ADDIE model. The instrument's effectiveness refers to the empirical validity after applying the STDT instrument. The effectiveness of the STDT instrument was obtained through the correlation of misconceptions experienced by students with the level of difficulty of the items. The STDT instrument was applied to 86 students. Results: The percentage of students who experienced the highest misconceptions occurred in the chemical equilibrium section of the equilibrium shift due to the influence of a catalyst. In each item of questions, most students need more knowledge or knowledge. The composition of the difficulty of these items should be considered from the start of the instrument's preparation. In the developed STDT instrument, the item difficulty obtained from empirical trials on students did not meet the ideal conditions for the composition of the item difficulty level. Novelty: The resulting instrument for detecting misconceptions. It is a tier diagnostic test that is integrated with three scientific questions.