bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic literature review and bibliometric analysis of leadership influence on employee unethical pro-organisational behaviour
Authors: Manelkar Shekhar , Mishra Dharmesh K. 
Published: February 2024

Purpose
Since the idea of “Unethical Pro-organisational Behaviour” (UPB) was introduced in 2010, a substantial corpus of empirical research has contributed to its expanding, contemporary knowledge. This includes research studies on how leadership exerts an influence on UPB. This paper aims to consolidate the current understanding of organisational leadership’s impact on employee UPB and offer future research agendas.

Design/methodology/approach
A systematic literature review (SLR) using the “Preferred Reporting Items for Systematic Reviews and Meta-Analyses” (PRISMA) guidelines was adopted for the study. Literature that satisfied the search conditions was examined. The factors determining leadership’s influence on UPB were studied, and the findings were thematically synthesised.

Findings
Leader behaviour plays a large part in influencing UPB in organisations. Leader-member exchange and organisational belonging create favourable circumstances for UPB in organisations. UPB is moderated by the employee’s personal moral orientation.

Originality/value
UPB is unethical behaviour that benefits the organisation and is likely to be rewarded. However, there is a cost that other stakeholders pay. UPB has been researched since 2010, as well as the role of leaders in perpetuating UPB. However, there has not been an SLR of this study. This paper seeks to capture the essence of the research so far and pave a path for future research on the subject. These insights would prove valuable to management practitioners and academic experts.
Igniting work innovation: performance pressure, extraversion, feedback seeking and innovative behavior
Authors: Arun Kumar P. , Lavanya V. 
Published: February 2024

PurposeThis study investigates how performance pressure affects feedback-seeking and innovative work behaviors. The study also examines the effect of extraversion on the performance pressure–FSB relationship.Design/methodology/approachThe hypotheses in this study were tested by analyzing two-wave data collected from a sample of employees in the information technology sector in India using the PLS-SEM approach.FindingsOur findings revealed that individuals possessing extraverted personality traits exhibited a positive response to performance pressure, thereby enhancing their FSB. Moreover, our results demonstrated that FSB mediates the relationship between performance pressure and IWB.Research limitations/implicationsThe results underscore the importance of individual variations in personality traits, particularly extraversion, in influencing how employees respond to performance pressure. By providing insights into the mediating mechanism of feedback-seeking behavior, our study contributes to a deeper understanding of the interplay between performance pressure, feedback-seeking behavior and innovative work behavior.Practical implicationsManagers should consider extraversion as a factor in the relationship between performance pressure and FSB, adapting strategies and support systems accordingly. Creating a feedback-oriented culture and providing resources for extroverts during high-pressure periods can enhance their coping mechanisms.Originality/valuePrevious research has provided a limited exploration of the mechanisms that establish the connection between job demands and innovative work behaviors. This study contributes by uncovering the previously unexplored relationship between performance pressure, extraversion, feedback-seeking behavior and, subsequently, innovative work behavior.
Doing business in Russia: normative organizational resilience, organizational identity and exit decisions
Authors: Avioutskii Viatcheslav , Roth Fabrice 
Published: February 2024

PurposeOur study examines multinational enterpris (MNE) decisions to withdraw from the Russian market on moral grounds in reaction to the Russo–Ukrainian war. We investigate to what extent these decisions reflect the normative organizational resilience of MNEs under institutional pressures in Russia. We test the impact of various macro- (home democracy, institutional quality, stakeholder pressure) and micro-variables (ESG criteria) that define the organizational identities of MNEs in relation to their withdrawal decisions. Our sample comprises 1,648 companies from 55 countries doing business in Russia before the start of the conflict.Design/methodology/approachTo test our hypotheses, we perform a nuanced analysis using both latent constructs and regression analysis on data for 1,648 MNEs.FindingsOur results are in line with the foreign divestment literature, suggesting that MNEs are likely to exit normatively distant countries.Originality/valueIn this study, we explore the impact of organizational values on normative responses of MNEs to a geopolitical crisis. We introduce a normative organizational resilience construct to demonstrate how MNEs respond to institutional pressures in a host country, in this case Russia. Making exit decisions on moral grounds, MNEs have acted as social actors endowed with moral sense and intentionality, in conformity with their organizational values.
Creating a sustainable urban ecosystem: the Azheke village model
Authors: Wu Yuting , Azmi Athira , Ibrahim Rahinah , Ghafar Azmiah Abd , Salih Sarah Abdulkareem 
Published: February 2024

PurposeWith rapid urbanization, cities are facing various ecological and environmental problems. Living in harmony with nature is more important than ever. This paper aims to evaluate the ecosystem and ecological features of Azheke village, a key component of the Hani Rice Terraces World Cultural Heritage in China. The focus is on exploring effective ways to improve the relationship between humans and the natural environment through urban design in order to create a livable and sustainable city that can promote the development of sustainable smart urban ecology design.Design/methodology/approachThis study conducted a systematic literature review to answer the following research questions: (1) How does Azheke design achieve harmony between humans and nature? (2) What are the effective approaches to improve the relationship between humans and nature within urban ecosystems? (3) How can urban design learn and integrate from Azheke’s ecological features to improve the relationship between humans and nature?FindingsAzheke sustains long-term human-nature harmony through traditional ecological knowledge (TEK) and efficient natural resource use. By incorporating biophilic design and nature-based solutions from Azheke, along with biodiversity-friendly urban planning, we can boost urban ecosystem health and create unique Azheke-inspired urban designs.Research limitations/implicationsThis research primarily focuses on the human-nature relationship, exploring design strategies based on biodiversity without delving into the interactions between other components of urban ecosystems, such as social-cultural and economic components.Originality/valueThis paper provides a new perspective and strategies for developing sustainable and smart urban ecology design. These findings can provide theoretical references for urban planners, designers and decision-makers.
An advanced exploration of functionalities as the underlying principles of construction control metrics
Authors: Sheikhkhoshkar Moslem , Bril El Haouzi Hind , Aubry Alexis , Hamzeh Farook 
Published: February 2024

PurposeIn academics and industry, significant efforts have been made to lead planners and control teams in evaluating project performance and control. In this context, numerous control metrics have been devised and put into practice, often with little emphasis on analyzing their underlying concepts. To cover this gap, this research aims to identify and analyze a holistic list of control metrics and their functionalities in the construction industry.Design/methodology/approachA multi-step analytical approach was conducted to achieve the study’s objectives. First, a holistic list of control metrics and their functionalities in the construction industry was identified. Second, a quantitative analysis based on social network analysis (SNA) was implemented to discover the most important functionalities.FindingsThe results revealed that the most important control metrics' functionalities (CMF) could differ depending on the type of metrics (lagging and leading) and levels of control. However, in general, the most significant functionalities include managing project progress and performance, evaluating the look-ahead level’s performance, measuring the reliability and stability of workflow, measuring the make-ready process, constraint management and measuring the quality of construction flow.Originality/valueThis research will assist the project team in getting a comprehensive sensemaking of planning and control systems and their functionalities to plan and control different dynamic aspects of the project.
An Integrated Experimental-Computational Study of Vocal Fold Vibration in Type I Thyroplasty
Authors: Avhad Amit , Wilson Azure , Sayce Lea , Li Zheng , Rousseau Bernard , Doyle James F. , Luo Haoxiang 
Published: February 2024

Abstract
Subject-specific computational modeling of vocal fold (VF) vibration was integrated with an ex vivo animal experiment of type 1 thyroplasty to study the effect of the implant on the vocal fold vibration. In the experiment, a rabbit larynx was used to simulate type 1 thyroplasty, where one side of the vocal fold was medialized with a trans-muscular suture while the other side was medialized with a silastic implant. Vocal fold vibration was then achieved by flowing air through the larynx and was filmed with a high-speed camera. The three-dimensional computational model was built upon the pre-operative scan of the laryngeal anatomy. This subject-specific model was used to simulate the vocal fold medialization and then the fluid-structure interaction (FSI) of the vocal fold. Model validation was done by comparing the vocal fold displacement with postoperative scan (for medialization), and by comparing the vibratory characteristics with the high-speed images (for vibration). These comparisons showed the computational model successfully captured the effect of the implant and thus has the potential for presurgical planning.
In vivo
pharmacodynamic characterization of a next-generation polyene, SF001, in the invasive pulmonary aspergillosis mouse model
Authors: Lepak Alexander J. , VanScoy Brian , Rubino Chris , Ambrose Paul G. , Andes David R. 
Published: February 2024

ABSTRACT

SF001 is a next-generation polyene antifungal drug in development, designed to have increased specificity to fungal ergosterol, which is absent in humans, and decreased binding to cholesterol. SF001 demonstrates long-acting, potent, broad-spectrum fungicidal activity. The goal of the current study was to determine the pharmacodynamic index and target of SF001 in an immunocompromised mouse model of invasive pulmonary aspergillosis against six
Aspergillus fumigatus
isolates. Minimum inhibitory concentration (MIC) values ranged from 0.5 to 2.0 mg/L. Plasma and epithelial lining fluid (ELF) pharmacokinetics were performed following single intraperitoneal doses of 1, 4, 16, and 64 mg/kg. Treatment efficacy was assessed with each of the six fungal isolates using daily doses of SF001 ranging from 0.25 to 64 mg/kg/day over a 96-h treatment duration. Efficacy was assessed by
A. fumigatus
quantitative PCR of conidial equivalents from lung homogenates. Nonlinear regression analysis using the Hill equation demonstrated that the 24-h exposure-response relationships for both plasma and ELF area under the concentration/MIC and
C
max
/MIC ratios were strong and relatively similar [coefficient of determination (
R
2
) = 0.74–0.75). Exposure-response relationships included a median plasma 24-h
C
max
/MIC target for stasis and 1-log kill endpoint of 0.5 and 0.6, respectively. The present studies demonstrated
in vitro
and
in vivo
SF001 potency against
A. fumigatus
. These results have potential relevance for SF001 clinical dose selection and evaluation of susceptibility breakpoints.
PKM2 induces mitophagy through the AMPK-mTOR pathway promoting CSFV proliferation
Authors: Liu Xiaodi , Yan Quanhui , Liu Xueyi , Wei Wenkang , Zou Linke , Zhao Feifan , Zeng Sen , Yi Lin , Ding Hongxing , Zhao Mingqiu , Chen Jinding , Fan Shuangqi 
Published: February 2024

ABSTRACT

Viruses exploit the host cell’s energy metabolism system to support their replication. Mitochondria, known as the powerhouse of the cell, play a critical role in regulating cell survival and virus replication. Our prior research indicated that the classical swine fever virus (CSFV) alters mitochondrial dynamics and triggers glycolytic metabolic reprogramming. However, the role and mechanism of PKM2, a key regulatory enzyme of glycolytic metabolism, in CSFV replication remain unclear. In this study, we discovered that CSFV enhances PKM2 expression and utilizes PKM2 to inhibit pyruvate production. Using an affinity purification coupled mass spectrometry system, we successfully identified PKM as a novel interaction partner of the CSFV non-structural protein NS4A. Furthermore, we validated the interaction between PKM2 and both CSFV NS4A and NS5A through co-immunoprecipitation and confocal analysis. PKM2 was found to promote the expression of both NS4A and NS5A. Moreover, we observed that PKM2 induces mitophagy by activating the AMPK-mTOR signaling pathway, thereby facilitating CSFV proliferation. In summary, our data reveal a novel mechanism whereby PKM2, a metabolic enzyme, promotes CSFV proliferation by inducing mitophagy. These findings offer a new avenue for developing antiviral strategies.

IMPORTANCE
Viruses rely on the host cell’s material-energy metabolic system for replication, inducing host metabolic disorders and subsequent immunosuppression—a major contributor to persistent viral infections. Classical swine fever virus (CSFV) is no exception. Classical swine fever is a severe acute infectious disease caused by CSFV, resulting in significant economic losses to the global pig industry. While the role of the metabolic enzyme PKM2 (pyruvate dehydrogenase) in the glycolytic pathway of tumor cells has been extensively studied, its involvement in viral infection remains relatively unknown. Our data unveil a new mechanism by which the metabolic enzyme PKM2 mediates CSFV infection, offering novel avenues for the development of antiviral strategies.
Agnodice: indexing experimentally supported bacterial sRNA-RNA interactions
Authors: Kotsira Vasiliki , Skoufos Giorgos , Alexiou Athanasios , Zioga Maria , Tastsoglou Spyros , Kardaras Filippos S. , Perdikopanis Nikos , Elissavet Zacharopoulou , Gouzouasis Vasileios , Charitou Theodosia , Hatzigeorgiou Artemis G. 
Published: February 2024

ABSTRACT

In the last decade, the immense growth in the field of bacterial small RNAs (sRNAs), along with the biotechnological breakthroughs in Deep Sequencing permitted the deeper understanding of sRNA-RNA interactions. However, microbiology is currently lacking a thoroughly curated collection of this rapidly expanding universe. We present Agnodice (
https://dianalab.e-ce.uth.gr/agnodice
), our effort to systematically catalog and annotate experimentally supported bacterial sRNA-RNA interactions. Agnodice, for the first time, incorporates thousands of bacterial sRNA-RNA interactions derived from a diverse set of experimental methodologies including state-of-the-art Deep Sequencing interactome identification techniques. It comprises 39,600 entries which are annotated at strain-level resolution and pertain to 399 sRNAs and 12,137 target RNAs identified in 71 bacterial strains. The database content is exclusively experimentally supported, incorporating interactions derived via low yield as well as state-of-the-art high-throughput methods. The entire content of the database is freely accessible and can be directly downloaded for further analysis. Agnodice will serve as a valuable source, enabling microbiologists to form novel hypotheses, design/identify novel sRNA-based drug targets, and explore the therapeutic potential of microbiomes from the perspective of small regulatory RNAs.

IMPORTANCE

Agnodice (
https://dianalab.e-ce.uth.gr/agnodice
) is an effort to systematically catalog and annotate experimentally supported bacterial small RNA (sRNA)-RNA interactions. Agnodice, for the first time, incorporates thousands of bacterial sRNA-RNA interactions derived from a diverse set of experimental methodologies including state-of-the-art Next Generation Sequencing interactome identification techniques.
The role of GpsB in
Staphylococcus aureus
cell morphogenesis
Authors: Costa Sara F. , Saraiva Bruno M. , Veiga Helena , Marques Leonor B. , Schäper Simon , Sporniak Marta , Vega Daniel E. , Jorge Ana M. , Duarte Andreia M. , Brito António D. , Tavares Andreia C. , Reed Patricia , Pinho Mariana G. 
Published: February 2024

ABSTRACT

For decades, cells of the Gram-positive bacterial pathogen
Staphylococcus aureus
were thought to lack a dedicated elongation machinery. However,
S. aureus
cells were recently shown to elongate before division, in a process that requires a shape elongation division and sporulation (SEDS)/penicillin-binding protein (PBP) pair for peptidoglycan synthesis, consisting of the glycosyltransferase RodA and the transpeptidase PBP3. In ovococci and rod-shaped bacteria, the elongation machinery, or elongasome, is composed of various proteins besides a dedicated SEDS/PBP pair. To identify proteins required for
S. aureus
elongation, we screened the Nebraska Transposon Mutant Library, which contains transposon mutants in virtually all non-essential staphylococcal genes, for mutants with modified cell shape. We confirmed the roles of RodA/PBP3 in
S. aureus
elongation and identified GpsB, SsaA, and RodZ as additional proteins involved in this process. The
gpsB
mutant showed the strongest phenotype, mediated by the partial delocalization from the division septum of PBP2 and PBP4, two penicillin-binding proteins that synthesize and cross-link peptidoglycan. Increased levels of these PBPs at the cell periphery versus the septum result in higher levels of peptidoglycan insertion/crosslinking throughout the entire cell, possibly overriding the RodA/PBP3-mediated peptidoglycan synthesis at the outer edge of the septum and/or increasing stiffness of the peripheral wall, impairing elongation. Consequently, in the absence of GpsB,
S. aureus
cells become more spherical. We propose that GpsB has a role in the spatio-temporal regulation of PBP2 and PBP4 at the septum versus cell periphery, contributing to the maintenance of the correct cell morphology in
S. aureus
.

IMPORTANCE

Staphylococcus aureus
is a Gram-positive clinical pathogen, which is currently the second cause of death by antibiotic-resistant infections worldwide. For decades,
S. aureus
cells were thought to be spherical and lack the ability to undergo elongation. However, super-resolution microscopy techniques allowed us to observe the minor morphological changes that occur during the cell cycle of this pathogen, including cell elongation.
S. aureus
elongation is not required for normal growth in laboratory conditions. However, it seems to be essential in the context of some infections, such as osteomyelitis, during which
S. aureus
cells apparently elongate to invade small channels in the bones. In this work, we uncovered new determinants required for
S. aureus
cell elongation. In particular, we show that GpsB has an important role in the spatio-temporal regulation of PBP2 and PBP4, two proteins involved in peptidoglycan synthesis, contributing to the maintenance of the correct cell morphology in
S. aureus
.
Precambrian to Pleistocene 40Ar/39Ar dating of clinopyroxene-hosted melt inclusions
Authors: Jicha Brian R. , Schaen Allen J. , Wathen Bryan , Nachlas William O. 
Published: February 2024

Abstract
Clinopyroxene is a rock-forming mineral that commonly hosts melt inclusions in mafic to intermediate composition volcanic and plutonic rocks. It is highly resistant to alteration compared to other co-existing phenocrysts such as plagioclase. Several recent studies have 40Ar/39Ar dated clinopyroxene in Neoproterozoic to Miocene basalts and dolerites. To assess the viability of the technique at the youngest end of the geologic time scale, we performed 40Ar/39Ar incremental heating experiments on clinopyroxene-hosted melt inclusions from a variety of mafic lithologies and tectonic settings. Most samples produced precise plateau ages including several Quaternary basalts to andesites as young as 0.6 Ma. All data are indistinguishable from new and/or published 40Ar/39Ar ages on groundmass or plagioclase from the same samples. The source of potassium (K) and resulting 40Ar* within clinopyroxene has been debated, but thus far has only been inferred based on 40Ar/39Ar data. Using electron probe microanalysis (EPMA) we show that there is negligible K in the clinopyroxene host, but substantial K (e.g., 1–4 wt%) in trapped melt inclusions and minor amounts in plagioclase inclusions. Thus, melt inclusions, which are common in phenocrysts in basaltic magmas, can be used to obtain accurate and precise 40Ar/39Ar ages for difficult-to-date volcanic and plutonic rocks from the Precambrian to the Pleistocene.
Intersection between tectonic faults and magmatic systems promotes swarms with large-magnitude earthquakes around the Tengchong volcanic field, southeastern Tibetan Plateau
Authors: Liu Min , Tan Yen Joe , Lei Xinglin , Li Hongyi , Zhang Yunpeng , Wang Weitao 
Published: February 2024

Abstract
Volcanic regions commonly host swarms comprising small to moderate-sized earthquakes while tectonic faults host mostly mainshock-aftershock sequences that can include very large earthquakes. In the southeastern Tibetan Plateau, large tectonic faults formed by the collision between the Indian and Eurasian plates intersect with the intraplate Tengchong volcanic field, and the seismic behavior of such an environment remains unclear. Here, we built a deep-learning-based high-precision earthquake catalog for the Tengchong volcanic field and found that (1) ~59% of the seismicity occurred as swarms but on faults aligned with the regional tectonic stress field; (2) all swarms contained fluid-diffusion-like migration fronts, with some occurring where high CO2 emissions have been detected; and (3) a year-long swarm, including two ML 5.2 earthquakes within two months, revealed complex fluid-fault interaction. Combined with the historical occurrences of M &gt;6 earthquake swarms around the Tengchong volcanic field, our observations suggest potential increased likelihood of swarms with large-magnitude earthquakes where large tectonic faults and magmatic systems intersect.