bluuebunny/crossref_metadata_2025_split huggingface dataset:
Absolute Quantification of Donor-Derived Cell-Free DNA in Pediatric and Adult Patients After Heart Transplantation: A Prospective Study
Authors: Böhmer Jens , Wasslavik Carina , Andersson Daniel , Ståhlberg Anders , Jonsson Marianne , Wåhlander Håkan , Karason Kristjan , Sunnegårdh Jan , Nilsson Staffan , Asp Julia , Dellgren Göran , Ricksten Anne 
Published: October 2023

In this prospective study we investigated a cohort after heart transplantation with a novel PCR-based approach with focus on treated rejection. Blood samples were collected coincidentally to biopsies, and both absolute levels of dd-cfDNA and donor fraction were reported using digital PCR. 52 patients (11 children and 41 adults) were enrolled (NCT03477383, clinicaltrials.gov), and 557 plasma samples were analyzed. 13 treated rejection episodes &gt;14 days after transplantation were observed in 7 patients. Donor fraction showed a median of 0.08% in the cohort and was significantly elevated during rejection (median 0.19%, p &lt; 0.0001), using a cut-off of 0.1%, the sensitivity/specificity were 92%/56% (AUC ROC-curve: 0.78). Absolute levels of dd-cfDNA showed a median of 8.8 copies/mL and were significantly elevated during rejection (median 23, p = 0.0001). Using a cut-off of 7.5 copies/mL, the sensitivity/specificity were 92%/43% for donor fraction (AUC ROC-curve: 0.75). The results support the feasibility of this approach in analyzing dd-cfDNA after heart transplantation. The obtained values are well aligned with results from other trials. The possibility to quantify absolute levels adds important value to the differentiation between ongoing graft damage and quiescent situations.
Thickness-Dependent Terahertz Permittivity of Epitaxially Grown PbTe Thin Films
Authors: Kawahala Nicolas M. , Matos Daniel A. , Rappl Paulo H. O. , Abramof Eduardo , Baydin Andrey , Kono Junichiro , Hernandez Felix G. G. 
Published: October 2023

The exceptional thermoelectric properties of PbTe are believed to be associated with the incipient ferroelectricity of this material, which is caused by strong electron–phonon coupling that connects phononic and electronic dynamics. Here, we have used terahertz time-domain spectroscopy measurements to generate complex permittivity spectra for a set of epitaxially grown PbTe thin films with thicknesses between 100 nm and 500 nm at temperatures from 10 K to 300 K. Using a Drude–Lorentz model, we retrieved the physical parameters of both the phononic and electronic contributions to the THz permittivity. We observed a strong decrease, or softening, of the transverse optical phonon mode frequency with decreasing temperature, determining a thickness-independent negative ferroelectric-transition critical temperature, while we found a thickness-dependent anharmonic phonon decay lifetime. The electronic contribution to the permittivity was larger in thinner films, and both the carrier density and mobility increased with decreasing temperature in all films. Finally, we detected a thickness-dependent longitudinal optical phonon mode frequency, indicating the presence of plasmon–phonon coupling.
FvbHLH1 Regulates the Accumulation of Phenolic Compounds in the Yellow Cap of Flammulina velutipes
Authors: Zeng Jiangyi , Shi Dingding , Chen Ying , Bao Xuemei , Zong Yuan 
Published: October 2023

Flammulina velutipes is a renowned edible and medicinal fungus. Commercially cultivated F. velutipes occurs in two distinct phenotypes: white and yellow. However, the underlying mechanism contributing to the yellow phenotype and high nutritional value remain uncertain. We reconfirmed that the browning process in F. velutipes is attributable to melanin accumulation, although the initial yellow cap seemed unrelated to melanin. A transcriptomic and metabolomic joint analysis revealed that 477 chemical compounds categorized into 11 classes, among which 191 exhibited significantly different levels of accumulation between different phenotypes. Specifically, 12 compounds were unique to the yellow F. velutipes, including ferulic acid, and 3-Aminosalicylic acid. Free fatty acids and xanthine were identified as the primary compounds correlating with the yellow and oily cap. A total of 44,087 genes were identified, which were more homologous to Pleurotus ostreatus PC15. Structural genes such as PAL (phenylalanine ammonialyase), C4H (cinnamate 4-hydroxylase), C3H (Coumarin-3-hydroxylase), AoMT (caffeoyl coenzyme A-O-methyltransferase), and 4CL (4-coumarate: CoA ligase) were up-regulated, thereby activating the lignin biosynthesis and metabolism pathway. Additionally, FvbHLH1 can lead to the consumption of a huge amount of phenylalanine while generating flavonoids and organic acid compounds. Meanwhile, ferulic acid biosynthesis was activated. Therefore, this study clarifies the chemical and molecular bases for the yellow phenotype and nutritional value of F. velutipes.
Closed Timelike Curves Induced by a Buchdahl-Inspired Vacuum Spacetime in R2 Gravity
Authors: Nguyen Hoang Ky , Lobo Francisco S. N. 
Published: October 2023

The recently obtained special Buchdahl-inspired metric Phys. Rev. D 107, 104008 (2023) describes asymptotically flat spacetimes in pure Ricci-squared gravity. The metric depends on a new (Buchdahl) parameter k˜ of higher-derivative characteristic, and reduces to the Schwarzschild metric, for k˜=0. For the case k˜∈(−1,0), it was shown that it describes a traversable Morris–Thorne–Buchdahl (MTB) wormhole Eur. Phys. J. C 83, 626 (2023), where the weak energy condition is formally violated. In this paper, we briefly review the special Buchdahl-inspired metric, with focuses on the construction of the Kruskal–Szekeres (KS) diagram and the situation for a wormhole to emerge. Interestingly, the MTB wormhole structure appears to permit the formation of closed timelike curves (CTCs). More specifically, a CTC straddles the throat, comprising of two segments positioned in opposite quadrants of the KS diagram. The closed timelike loop thus passes through the wormhole throat twice, causing two reversals in the time direction experienced by the (timelike) traveller on the CTC. The key to constructing a CTC lies in identifying any given pair of antipodal points (T,X) and (−T,−X) on the wormhole throat in the KS diagram as corresponding to the same spacetime event. It is interesting to note that the Campanelli–Lousto metric in Brans–Dicke gravity is known to support two-way traversable wormholes, and the formation of the CTCs presented herein is equally applicable to the Campanelli–Lousto solution.
Analisis Faktor – Faktor yang Mempengaruhi Minat Penggunaan Uang Elektronik (LinkAja)
Authors: Dianti Muthia Rahma , Dwi Zulstra Jumadil , Rahim Hamidah 
Published: October 2023

Payment systems have been evolving along with technological developments, from the barter system in ancient times to today’s non-cash payment instruments. Electronic money is the newest non-cash payment instrument. The purpose of this paper is to explore the factors that influence postgraduate students’ intention to use LinkAja Application. This research was done in Padang, West Sumatra. A questionnaire was developed from the 160 postgraduate students from three universities in Padang who have LinkAja accounts yet or experience before. The model used here had been developed from the Technology Acceptance Model integrated with the perceived risk theory, five specific risk–performances, financial, security/privacy, social, and time risk was tested on a sample of postgraduate students to explain postgraduate student’s behavioral intention to use LinkAja. A quantitative research method was employed utilizing the survey method. Data were analyzed using the Structural Equation Model technique. The results reveal that perceived usefulness and perceived ease of use consistently have significant and positive impacts on behavioral intention to use LinkAja. However, perceived risk has no significant impact on behavioral intention to use LinkAja. This study confirmed the TAM model is important factor for predicting postgraduate students’ behavioral intention to use LinkAja in Padang Universities.
Microwave Energy Harvesting With No Extra Receiving Antenna
Authors: YAŞLI Ahmet , ÜLKER Sadık 
Published: October 2023

This paper addresses different cases of radio frequency harvesting using different antenna types as
transmitting antenna but using just the lead of the capacitor as the wire antenna at the receiving end
with a voltage rectifier circuit. Different antennas were used in the input and with two different
rectification circuits the conversion efficiencies were studied accordingly. For a source of log periodic
antenna, without any antenna, 27.31% RF-DC power conversion efficiency value was obtained at the
far-field. For a source of half wavelength dipole antenna, at the near-field, 50.53% RF-DC power
conversion efficiency value was obtained. For a source of helical antenna, up to 5 cm distance about
14.78% RF-DC power conversion efficiency was observed. For the Yagi-Uda antenna used as a source,
RF-DC power conversion efficiency that was obtained at the far was 28.89% without any receiving
antenna..
Jenerik Katı Bir Füze Kanat Geometrisinin Doğal Frekans Değerlerinin Çok Amaçlı Geometrik Optimizasyonu
Authors: TOLA Ceyhun , AKSEN Ukte 
Published: October 2023

Havadan karaya füze sistemlerini uzak mesafeden hedefe göndermek, taarruz eden hava platformunun
düşman unsurlarına mümkün olduğunca daha uzak kalmasını sağlamak açısından kritik öneme sahiptir.
Bu bağlamda, hâlihazırda kullanımda olan kanatsız mühimmatlar için kanat kitlerinin geliştirilmesi önem
kazanmıştır. Geliştirilen kanat kitleri, aerodinamik performans bakımından tatmin edici sonuçlar
sunmalı, uçuş sırasında karşılaşılabilecek en kritik yüklere dayanmalı ve kanadın en düşük doğal frekans
değeri kuyruk kontrolcüsünün manevra ve denge sağlama amacıyla uyguladığı müdahale frekansından
daha yüksek olmalıdır. Çalışma kapsamında, içi dolu metalik bir jenerik füze kanadının çok amaçlı
geometrik optimizasyonu parçacık sürü optimizasyonu yöntemi kullanılarak gerçekleştirilmiştir. Sonlu
elemanlar analizleri, Abaqus yazılımında parametrik model oluşturmak ve çözüm gerçekleştirmek
amacıyla hazırlanan Python kodu yardımıyla gerçekleştirilmiş; optimizasyon akışı ve çözümleri ise
ModeFrontier yazılımında yürütülmüştür. Kanat açıklığı boyunca kanadın kök, ara ve uç kesitinde
kullanılan kanat profilleri, kanat profil değişiminin gerçekleştiği ara kesitin köke olan mesafesi, uç ve ara
kesitteki veter uzunlukları, kökten ara kesite ve ara kesitten kanat ucuna olan ok açıları optimizasyon
değişkenleri olarak belirlenmiştir. Optimizasyon kapsamında, kanat alanının ve doğal titreşim analizleri
sonucunda elde edilen birinci moda ait doğal frekans değerinin maksimize edilmesi, kanat kütlesinin ise
minimize edilmesi hedeflenmiştir. Kanadın yeterli taşıma kuvvetini oluşturabilmesi için gerekli
minimum kanat alanı kısıt olarak tanımlanmıştır. Ayrıca kökten uca doğru kanat profillerinin sabit
kalması ya da doğrusal olarak incelmesi ve sivrilmesini sağlayacak kısıtlar tanımlanmıştır. Optimizasyon
sonucunda 1897 adet uygulanabilir, 1107 adet kısıtları ihlal eden ve dolayısıyla uygulanamayan çözüm
elde edilmiştir. Son olarak, girdi parametrelerinin kanadın birinci titreşim modunun doğal frekans değeri
üzerindeki etkileri hassasiyet analizi sonucunda belirlenmiştir.
Grafen Oksit/Altın/Polianilin Nanokompozitlerinin Eş Zamanlı Çöktürme/Polimerizasyon Yöntemleriyle Sentezi ve Fototermal Performansı
Authors: SOYSAL Furkan , ÇIPLAK Zafer 
Published: October 2023

Bu çalışmada, grafen oksit (GO) üzerinde tek basamakta altın tuzunun (HAuCl4) indirgenmesi ve anilin
monomerinin polimerize edilmesiyle GO/Au/Polianilin (PANI) nanokompozitleri faklı bileşimlerde
sentezlenmiş, karakterize edilmiş ve 808 nm dalgaboyuna sahip bir lazer ile fototermal özellikleri
incelenmiştir. 1.5 W/cm2 lazer güç yoğunluğunda 0.1 mg/mL derişime sahip nanokompozit
dispersiyonları arasında 10 dakikalık ısıtma işlemi sonucunda ulaşılan en yüksek sıcaklık GO1-Au-PANI4
nanokompozitinde 62.6 °C, en yüksek fototermal dönüşüm verimi ise 0.384 olmuştur. Bu nanokompozit
üzerinde tekrarlı ısıtma soğutma deneyleri gerçekleştirilmiş ve ulaşılan en yüksek sıcaklıkta kayda değer
bir değişiklik gözlenmemiştir. GO/Au/PANI nanokompozitinin tek basamaklı kolay sentez yöntemi ve
yüksek fototermal performansı ile umut verici bir fotoajan olduğu tespit edilmiştir.
Chaotic Snake Optimizer
Authors: YILDIZDAN Gülnur 
Published: October 2023

Metaheuristic algorithms provide approximate or optimal solutions for optimization problems in a
reasonable time. With this feature, metaheuristic algorithms have become an impressive research area
for solving difficult optimization problems. Snake Optimizer is a population-based metaheuristic
algorithm inspired by the mating behavior of snakes. In this study, different chaotic maps were
integrated into the parameters of the algorithm instead of random number sequences to improve the
performance of Snake Optimizer, and Snake Optimizer variants using four different chaotic mappings
were proposed. The performances of these proposed variants for eight different chaotic maps were
examined on classical and CEC2019 test functions. The results revealed that the proposed algorithms
contribute to the improvement of Snake Optimizer performance. In the comparison with the literature,
the proposed Chaotic Snake Optimizer algorithm found the best mean values in many functions and
took second place among the algorithms. As a result of the tests, Chaotic Snake Optimizer has been
shown to be a promising, successful, and preferable algorithm.
Molten Salt Approach for Co3O4 Synthesis as a Charge Storage Electrode
Authors: KURTAN Ümran 
Published: October 2023

A versatile molten salt method was targeted to fabricate the cobalt oxide (Co3O4) nanospheres as
charge storage electrodes. The Co3O4 nanospheres were prepared in KNO3 molten salt in only one step
within 5 minutes. The nanospheres were with an average size distribution of almost 80-130 nm. The
specific capacitance of cobalt oxide was found to be 285 F/g at 10 mV/s and 171 F/g at 0.5 A /g in 6 M
KOH and the Trasatti method was used to understand the outer and inner surface capacitive
contributions. The material possessed a moderate rate capability (63.1% at 5 A/g) and had good cyclic
stability (90.5% after 1200 cycles). This experimental study does not require any solvent usage and thus
can provide a green and continuous approach for the preparation of various transition metal oxides
with good electrochemical properties in the energy storage field.
Mask R-CNN ile Mikroskobik İdrar Görüntüsü İçeriklerinin Tespiti
Authors: YÖRÜK Yunus Emre , SARAOĞLU Hamdi Melih , ÖZER Ömer Faruk 
Published: October 2023

Mikroskobik idrar içerikleri doğru ve dikkatli bir şekilde analiz edildiğinde vücut hakkında önemli bilgiler
verir. İdrar tahlilinin insan sağlığı için önemi nedeniyle mikroskobik idrar içeriklerinin tespit edilmesi
amacıyla derin öğrenme görüntü işleme tekniği kullanılarak yapay zeka uygulamaları yapılmıştır.
Literatürde yer alan çalışmaların çoğunda genel olarak semantik segmentasyon üzerine yoğunlaşılmıştır.
Bu çalışmada ise piksel düzeyinde segmentasyon yapabilen Mask R-CNN modeli ile mikroskobik idrar
görüntülerindeki alyuvar, akyuvar, epitel, kristal, bakteri ve mantar içerikleri konum ve nesne türü
bilgisiyle birlikte tespit edilmiştir. Mask R-CNN ile tespit edilen nesnelere maske ve çerçeve olmak üzere
iki tip sınır çizilmektedir. Sistemin performansı her iki sınır tipi için ayrı ayrı incelenmiştir. Test için
kullanılan 100 görüntüdeki toplam 1154 örüntüden maskelere göre 808 ve çerçevelere göre 843 nesne
doğru şekilde tespit edilmiştir (IoU=0,5). En iyi tespit oranı akyuvarlar ve alyuvarlar için gerçekleşmiştir.
Epiteller çerçevelere göre hesaplamada başarılı bir şekilde tespit edilmiştir fakat düzgün maske
oluşturulamamıştır. Bakteriler diğerlerine göre çok küçük olduğu için doğru tespit oranı düşük kalmıştır.
Kristallerin ve mantarların çoğu doğru şekilde tespit edilmiştir. Ayrıca, nesne tespitinde sıklıkla kullanılan
değerlendirme metriği mAP de hesaplanmıştır. Sistem için hesaplanan mAP değerleri maskelere göre
0,7842 ve çerçevelere göre 0,8343 olmuştur. Mask R-CNN sistemi iyi bir şekilde optimize edilip daha
fazla idrar içeriğine ait görüntülerle eğitilmesi durumunda idrar analiz sistemlerinde kullanılabilir.
AI Embodiment Through 6G: Shaping the Future of AGI
Authors: Bariah Lina , Debbah Merouane 
Published: October 2023

<p>In the ever-evolving field of technologies, the emergence of Artificial General Intelligence (AGI), often referred as strong artificial intelligence (AI), stands as a breakthrough in the realm of machines intelligence, promising to witness a new era of capabilities and possibilities. In particular, AGI ventures into human-level cognition, and expands to thinking, reasoning, and awareness. This imminent evolution is envisioned to be manifested through the embodiment of AI machines, allowing machines to transcend their purely computational nature and interact with the world through the different senses. Accordingly, AI agents will be grounded in the physical environment, going through subjective experiences and acquiring the needed knowledge that will lead to understanding and cognition. In our article, we explore the path towards realizing the true vision of AGI through AI embodiment, where we dig into the different types of thinking required to achieve knowledge, and hence, cognition and understanding. Furthermore, we look through the evolution of generative AI models, and shed lights on the limitations of auto-regression in large language models (LLMs), with the aim to answer the question: is sensory grounding (through 6G) necessary, and enough, to achieve understanding in LLMs? Finally, we identify the main pillars of AGI and unveil how 6G networks will orchestrate the development of AGI systems. </p>
PENYULUHAN SEBAGAI UPAYA MENINGKATKAN PENGETAHUAN TENTANG OSTEOARTHRITIS PADA KOMUNITAS LANSIA DI POSYANDU DESA SUTOJAYAN
Authors: Rachmawati Miranti Ika , Rahmanto Safun , Ayu S.P. Herdiana 
Published: October 2023

Osteoarthritis (OA) adalah penyakit sendi degeneratif dan berdampak cukup besar pada individu pasien secara keseluruhan, mengakibatkan rasa nyeri, kecacatan, dan mempengaruhi aktivitas social dimasyarakat yang mempengaruhi >25% dari populasi di atas 18 tahun. Pengetahuan dan pemahaman mengenai osteoarthritis dimasyarakat sampai saat ini masih sangat kurang, oleh sebab itu penyuluhan merupakan salah satu kegiatan yang bisa dilakukan untuk menambah pengetahuan dan pemahaman mengenai osteoarthritis. Kegiatan penyuluhan yang diadakan diharapakan menambah pengetahuan serta pemahaman bagi komunitas lansia di poyandu desa Sutojayan. Metode yang digunakan dalam penyuluhan kali ini adalah dengan memberikan leafet dan memberikan beberapa pertanyaan pretest posttest untuk mengetahui gambaran pengatahuan pada komunitas lansia di posyandu desa Sutojayan. Hasil dari kegiatan ini terdapat 15 orang yang bersedia mengikuti penyuluhan dan didapatkan hasil posttest dari peserta yang mengikuti penyuluhan mengalami peningkatan pengetahuan. Dapat disimpulkan bahwa kegiatan penyuluhan yang dilakukan dapat memperbaiki serta menambah pengetahuan mengenai osteoarthritis.
Education PENDAMPINGAN BAGI FOS PSK (PEDULI SESAMA KITA) MELALUI PROGRAM LITTLE STAR CERDAS BERBAHASA INGGRIS DI DESA KETING, JEMBER
Authors: Yaqin Moh. Nazib Abdulloh , Putri Cendy Nur Faizah , Dwi Gresafril Wisnu , Chayyuna Aulia , Kuncoro Rishad Kurniawan 
Published: October 2023

Pendidikan merupakan suatu proses pembelajaran meliputi pengajaran suatu keahlian, pemberian pengetahuan,pertimbangan dan kebijaksanaan. Jalur pendidikan terdiri dari dua macam yaitu pendidikan formal yaitu melalui sekolah dan pendidikan nonformal yaitu di luar sekolah. Pendidikan di luar sekolah atau nonformal dilakukan untuk menunjang atau menambah pengetahuan siswa mengenai pembelajaran materi di sekolah. Desa Keting Kabupaten Jember memiliki suatu organisasi sosial independen dengan nama FOS PSK ( Forum Organisasi Sosial Peduli Sesama Kita) . Organisasi ini memiliki program bernama Little Star yang memberikan pengajaran pada anak usia TK dan SD dalam mata pelajaran bahasa Inggris untuk meningkatkan pengeahuan dan pemahaman mereka. Penelitian ini menggambarkan mahasiswa KKN Kolaboratif dalam kunjungan dan kegiatan pendampingan di FOS PSK (Peduli Sesama Kita) dalam program Little Star. Metode yang digunakan adalah metode wawancara dan pelaksanaan. Wawancara dilakukan antara mahasiswa dan pengurus dan pengajar PSK untuk mengetahui kondisi dari pemahaman Bahasa Inggris dan masalah yang dihadapi dari program Little Star. Pelaksanaan pendampingan dilakukan oleh mahasiswa dengan disertai oleh pengajar PSK selama dua kali pada hari Minggu. Kegiatan pendampingan yang dilakukan terdiri dari beberapa kegiatan yaitu senam,pemberian materi, dan latihan soal yang dipadukan dengan permainan berhadiah. Anak – anak Little Star menunjukkan minat yang tinggi dalam belajar Bahasa Inggris karena adanya pembelajaran yang dipadukan dengan permainan berhadiah.
PENGARUH PENAMBAHAN REMAZOL YELLOW TERHADAP EFEKTIVITAS FOTOREDUKSI ION Cr(VI) TERKATALISIS TiO2-RESIN
Authors: A'yun Ayu Qurota , Ridho Rosyid 
Published: October 2023

Pengaruh Remazol Yellow terhadap efektivitas fotoreduksi ion Cr(VI) yang dikatalisis TiO2-Resin telahditeliti. Penelitian ini diawali dengan pembuatan katalisis TiO2-Resin dengan perbandingan 1:1. Hasil preparasi Katalis TiO2-Resin dikarakterisasi menggunakan difraksisinar-X. Kemudian katalisis TiO2-Resin diujikan untuk mereduksi ion Cr (V) dan mendegradasi senyawa Remazol Yellow dalam limbah. Proses fotoreduksi ion Cr(VI) dan fotodegradasi Remazol Yellow dilakukan di dalam suatu sistem reaktor tertutup (sistem batch) yang dilengkapi dengan lampu UV yaitu dengan cara menyinari campuran yang terdiridari ion Cr(VI) dan serbuk fotokatalis TiO2-Resin disertai pengadukan selama waktu tertentu. Dalam penelitian ini dipelajari pengaruh waktu penyinaran, konsentrasi awal ion Cr(VI) dan keberadaan Remazol Yellow terhadap efektivitas fotoreduksi. Hasil penelitian ini menunjukkan bahwa fotokatalis TiO2-Resin dapat meningkatkan hasil fotoreduksi ion Cr(VI) yaitu waktu 48 jam hasil fotoreduksi sebesar 82,83%. Pengaruh konsentrasi awal ion Cr(VI) diperoleh hasil fotoreduksi ion Cr(VI) yaitu 5 ppm sebesar 89,54%. Adanya penambahan Remazol Yellow mempengaruhi efektivitas fotoreduksi ion Cr(VI) sebesar 76,44% pada konsentrasi 5 ppm ion Cr(VI). Hasil Fotodegradasi Remazol Yellow hasilterbesar juga terdapat pada konsentrasi ion Cr(VI) 5 ppm sebesar 29,28%. Ketersediaanradikal •OH yang diperlukan untuk mengoksidasi Remazol Yellow dalam jumlah yang tetap dan relative banyakmembuatfotodegradasi Remazol Yellow meningkat. Hasil pengaruhvariasi Remazol Yellow terhadap efektivitas fotoreduksi ion Cr(VI) sebesar 78,46% pada konsentrasi Remazol Yellow 10 ppm. Adanya penambahan Remazol Yellow dapat meningkatkan reduksi ion Cr(VI) dan sebaliknya, hal ini dikarenakan keberadaan Remazol Yellow dapat mencegah penggabungan kembali •OH dan elektron.