bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Change of Symptom Clusters in Gastrointestinal Cancer Patients During the Perioperative Period: A Longitudinal Study
Authors: Wei Jianjian , Yan Hongxia , Yin Wen , He Fang 
Published: January 2024

Abstract
Aim and objectives:
The aim of this study was to describe the numbers, types, and trajectory of symptom clusters during the perioperative period in gastrointestinal cancer patients at four different time points. The study also aimed to identify the changes and consistency of these symptom clusters over time.
Design:
This was a longitudinal study.
Methods
This study conducted at a tertiary cancer hospital involving 205 gastrointestinal cancer patients. The M.D. Anderson Symptom Inventory Gastrointestinal Cancer Module was used to assess the incidence and severity of symptom clusters. Exploratory factor analysis was employed to extract the symptom clusters.
Results
The study identified four symptom clusters in gastrointestinal cancer patients during the perioperative period: gastrointestinal symptom cluster, physical symptom cluster, psychological symptom cluster, and sleep disturbance symptom cluster. These clusters were observed across two to four time points.
Conclusion
The findings of this study provide scientific evidence for medical staff and researchers to gain a better understanding of the symptom experiences of gastrointestinal cancer patients during the perioperative period. This knowledge can be valuable in developing individualized symptom management interventions.
Relevance to clinical practice
: Gastrointestinal cancer patients suffered from various symptom clusters and lasted from day before surgery to one month after surgery, which should be paid attention by clinical staff.
Comparative Study of Cognitive Behavior Therapy and Virtual Reality Exposure Therapy for PTSD Patients
Authors: Akhtar Shammem 
Published: January 2024

Abstract
INTRODUCTION: Posttraumatic stress disorder (PTSD) is a severe and multifarious anxiety disorder precipitated by exposure to psychotically stressful events that affects 5 to 10% of the population (Yehuda et al., 2015). It is characterized by constant disturbing memories about the traumatic event, consisting of escaping stimuli associated with the disturbance and persistent symptoms of increased stimulation. PTSD can be triggered by either bodily trauma or psychological trauma (APA, 2013). Among the most common traumatic I-e traffic accidents, earth quakes, floods, rape, and all other psychological problems, PTSD is most common (Huang, et al., 2010).
OBJECTIVEV: The objective of the present study was to analyse the effectiveness of cognitive therapy and EMDR therapy for PTSD patients with posttraumatic stress disorder.
MATERIAL AND METHODS: A purposive sampling method was used. Samples consisted of thirty known posttraumatic stress disordersamples taken from Nishtar Hospital Multan. TheMississippi Scale for Combat Related Post-Traumatic Stress Disorders (Keane et al., 1988) was used to measure the severity of posttraumatic stress disorder. Three groups were established as group one (A), in which ten patients were provided cognitive therapy. The second ten groups (B) were subjected to eye movement desensitization and reprocessing (EMDR). The third group was used as a control.
RESULTS: SPSS version 26 and an independent t test were used to determine the significance of the therapeutic efficacy. The results revealed a significant difference in the number of patients in the experimental group who received cognitive behaviour therapy (t=-3.588, df=18, p>0.05). Systematic desensitization for posttraumatic stress disorder (t=--2.527, df=18, p=0.05) was concluded.
Conclusions: Cognitive behaviour therapy is more effective for the rapid and better management of PTSD.
Coordination of Overcurrent and Distance Relays in Power System Networks with Distributed Generations
Authors: Majhi Abhilash Asit Kumar , Ray Papia , Biswal Monalisa , Arya Sabaraj 
Published: January 2024

Abstract
The integration of distributed generations (DGs) in power systems poses challenges in coordinating protection devices originally designed for a centralized generation. This study examines numerous scenarios for choosing and coordinating protection systems in presence & absence of DGs and provides a thorough analysis of how DGs impact protection coordination. The technique takes into account a variety of relay attributes and use Teaching Learning Based Optimization (TLBO) algorithm to ascertain ideal relay configuration that will enable most efficient coordination. Optimization techniques are employed to optimize the zones of distance relays and ensure a suitable coordination time interval (CTI) [0.2 sec or more]. Simulation results on real-time networks, such as the IEEE-9 and IEEE-30 bus test systems, demonstrate the effectiveness of the method in achieving optimal coordination. TSM and over-current relay characteristics are found for various cases and uniform values in every situation to prevent relay resets. Using the TSM and Characteristics values operating time of overcurrent relays and the operating time of the second zone of distance relays are found. The simulation outcomes showcase the ability of the method used to generate practical and feasible solutions.
Analysis of Losses in Physiotherapy Students During the Covid-19 Pandemic: A Phenomenological Approach
Authors: Pérez Marta Terrón , Amador Sara Cortés , Simeó Juan Bautista Portolés 
Published: January 2024

Abstract
Background
During the COVID 19 Pandemic situation, young people experienced numerous personal losses in many aspects, which impacted their quality of life.
Objective
To explore and analyse the losses in physiotherapy students during the first year of the COVID-19 pandemic.
Methods
A qualitative phenomenological study was carried out using an open format exercise carried out during the Clinical Specialties class from February-May 2021. Thirty-four (83% female) third-year physical therapy students participated. ATLAS.ti software was used for the analysis and coding of the data by three researchers.
Results
After the analysis of the categories, different losses by the participants were found: losses in psychological well-being, losses in physical health, losses in the social sphere (friendships, partners and family relationships, as well as deaths) and spiritual losses (loss of freedom and identity), losses in leisure time (travel, recreational activities and physical exercise) and different losses related to university studies (motivation and enthusiasm and clinical practices).
Conclusion
The COVID-19 pandemic has generated losses worldwide in physiotherapy students, with losses in the social sphere being the most expressed. The present study can be used to generate resources that improve the well-being of physiotherapy students, both for optimal academic performance and greater self-care, and reduce psychosocial problems.
In vitro and in silico anticoccidial activity of the seeds of Lepidium sativum red and black varieties
Authors: Alebachew Yonatan , Wondu Kebede ,   Tigist Getachew3, Tilahun Debora , Adamu Meskerem , Gebre-Mariam Tsige 
Published: January 2024

Abstract

Coccidiosis is a parasitic disease of major economic importance in the poultry industry. The exploration of natural alternative strategies such as phytochemicals is becoming significant in controlling coccidiosis. Therefore, in the present study, we investigate the in vitro anticoccidial activity of the seeds of red and black Lepidium sativum varieties that have multiple traditional medicinal uses and identify their major active components. The seeds of red and black L. sativum varieties were extracted with 80% methanol and tested for their in vitro anticoccidial activity using a sporulation inhibition assay. The 80% methanol extract of the red variety was solvent partitioned into four fractions, and each was tested for activity. Then, column chromatography of the active fractions was carried out to isolate compounds. The chemical structures of the compounds were determined by spectroscopic methods (1H, 13C and DEPT NMR). The 80 methanol extract of both the black and red varieties inhibited sporulation of oocysts by 83.71% and 98.27% at concentrations of 1000 mg/ml, respectively. Among all tested substances, the chloroform fraction, followed by the hexane, was found to be the most active one with sporulation inhibition values of 93.5% and 98.91% at 500 and 1000 mg/ml doses, respectively. Moreover, linoleic acid, alpha-linolenic acid and methyl sinapate were identified and characterized as the major components of the active fractions. Furthermore, molecular docking and conformational similarity scanning study of the compounds and anticoccidial drugs revealed that methyl sinapate had a strong binding affinity and conformational alignment to dihydrofolate reductase (HYDE score, -41.6 KJ/mol) and trimethoprim (FlexS scores, 0.84), respectively. In addition, to find further chemically similar analogs of methyl sinapate, we navigated the chemical space library of billions of commercially available synthetic compounds using the bioinformatics tool infiniSee 5.0.1 and identified 100 molecules with FlexS scores in the range of 0.67–0.78. These findings along with the safety profile derived from the acute oral toxicity tests of the extract suggest L. sativum as an alternative source of treatment for coccidiosis.
On the third ABC index of trees and unicyclic graphs
Authors: Song Rui 
Published: January 2024

Abstract
Let $G=(V,E)$ be a simple connected graph with vertex set $V(G)$ and edge set $E(G)$. The third atom-bond connectivity index, $ABC_3$ index, of $G$ is defined as $ABC_3(G)=\sum\limits_{uv\in E(G)}\sqrt{\frac{e(u)+e(v)-2}{e(u)e(v)}}$, where eccentricity $e(u)$ is the largest distance between $u$ and any other vertex of $G$, namely $e(u)=\max\{d(u,v)|v\in V(G)\}$. This work determines the maximal $ABC_3$ index of unicyclic graphs with any given girth and trees with any given diameter, and characterizes the corresponding graphs.
AMS Classification: 05C50
On the clinical interpretation of overground gait stability indices in children with cerebral palsy
Authors: Sangeux Morgan , Viehweger Elke , Romkes Jacqueline , Bracht-Schweizer Katrin 
Published: January 2024

Abstract

Several indices have been devised to quantify a person’s stability from its gait pattern during overground walking. However, clinical interpretation of the indices is difficult because the link between being stable and adopting a mechanically stable gait pattern may not be straightforward. This is particularly true for one of these indices, the margin of stability, for which opposite interpretations are available in the literature. We collected overground walking data in two groups of 20 children, with unilateral cerebral palsy (CP) and typically developing (TD), for two conditions, on flat and on uneven grounds (UG). We postulated that TD children were more stable during gait than children with CP and that both groups were more stable on flat compared to UG. We explored the coherent association between several indices and the two postulates to clarify clinical interpretation. Our results showed that increased margin of stability, increased amplitude of the whole-body angular momentum, decreased single limb support %, increased variability (gait kinematics, step length, and step width) were associated with reduced stability for both postulates. However, results for the margin of stability were paradoxical between the sides in the CP group where small margin of stability was indicative of a fall forward strategy on the affected side rather than improved stability. Whole-body angular momentum and single support % appeared as the most sensitive indices. However, walking speed influenced these and would need to be considered when comparing groups of different walking speed.
Network Algorithm to Model Automotive Supply Chain Structure
Authors: Barros José , Turner Christopher 
Published: January 2024

Abstract

In this study, we present a network algorithm that models the structure of automotive supply chains. We compiled a comprehensive dataset from a proprietary database, detailing automotive manufacturers and their suppliers across various tiers. An initial structural analysis was conducted using key performance indicators - including average path length, clustering coefficient, and degree distribution - to assess network configurations. The networks were then partitioned, with an emphasis on reflecting the operational dynamics of supply chain activities.
Regression analysis was applied to each network segment, using the number of vertices as the independent variable, to develop an algorithm for generating synthetic networks. These synthetic constructs serve as benchmarks for the automotive sector and have shown a strong average correlation (0.94) with the structure of actual supply networks. The prevalence of tree-like structures within these synthetic networks challenges conventional beliefs regarding the complexity of automotive supply chains and prompts further investigation into the determinants of their resilience.
Healthcare workers experience of screening older adults in emergency care settings: A qualitative descriptive study using the Theoretical Domains Framework
Authors: Barry Louise , Leahy Aoife , O’Connor Margaret , Ryan Damien , Corey Gillian , Tighe Sylvia Murphy , Galvin Rose , Meskell Pauline 
Published: January 2024

Abstract

In emergency care settings, screening for disease or risk factors for poor health outcomes among older adults can identify those in need of specialist and early intervention. The aim of this study was to identify barriers and facilitators to implementing older person-centred screening in emergency care settings in the Mid-West of Ireland.
Methods
This study employed a qualitative descriptive design underpinned by the theoretical domains framework (TDF). This design informs implementation strategy by establishing a theoretical foundation for focused objectives. One on one semi-structured interviews were conducted with a purposive sample of healthcare workers (HCWs) to explore their screening experiences with older adults in emergency care settings. Information power guided sample size calculation. In data analysis, verbatim interview transcripts were deductively mapped to TDF constructs forming meta-themes that revealed specific barriers and facilitators to person-centred screening for older individuals. These findings will directly inform implementation strategies.
Results
Three themes were identified; Preconditions to Implementing Older Person-Centred Screening; Knowledge and Skills Required to Implement Older Person-centred Screening and Motivation to Deliver Older Person-Centred Screening. Overall, screening in emergency care settings is a complicated process which is ideally undertaken by knowledgeable and skilled practitioners with a keen awareness of team dynamics and environmental challenges in acute care settings. These practitioners serve as champions and sources of specialist knowledge and practice. Less experienced clinicians seek supervision and support to undertake screening competently and confidently. Education on frailty and aged related syndromes facilitates screening uptake. Recognition of the value of screening is a clear motivator and leadership is vital to sustain screening practices.
Conclusions Screening serves as an entry point for specialist intervention, necessitating a specialist multidisciplinary team (MDT) approach for effective implementation in emergency care settings. Strengthening screening practices for older adults who attend emergency care settings involves employing audit, supervision and tailored supports. Skilled and experienced practitioners play a key role in mentoring and supporting the broader MDT in screening engagement. Long-term and sustainable implementation relies on utilising existing managerial, practice development and educational resources to underpin screening practices. Communication between ED staff, the specialist team and wider geriatric team is vital to ensure a cohesive approach to delivering older person-centred care in the ED.
Modified osteotomy for sternoclavicular graft harvest in temporomandibular joint ankylosis patients: A technical note
Authors: Mohanty Sujata , Verma Anjali , S Hemavathy 
Published: January 2024

Abstract
Purpose: Sternoclavicular grafts are considered structurally, histologically and functionally most similar to the temporomandibular joint (TMJ). The technique of split thickness sternoclavicular graft employing the superior segment of clavicle has remain unchanged despite the occurrence of adverse events in the intra-operative and post-operative period. The aim of this technical note is to describe a modified approach for sternoclavicular graft harvest and the advantages of its use.
Methods: Two patients with TMJ ankylosis underwent ramus condyle unit reconstruction (RCU) with sternoclavicular grafts harvested using this modified technique. The incidence of clavicle fracture, neurovascular injury, pleural rupture, and radiographic healing as demonstrated on the chest radiograph taken six months after surgery were each evaluated as donor site consequences.
Results: Using the current harvesting technique, no adverse events occurred in the intra-operative and post-operative periods.
Conclusion: The results of the present study suggest that the modified harvest technique is a useful and straight-forward method and constitutes a new alternative for the TMJ ankylosis patients requiring reconstruction with sternoclavicular grafts after osteoarthrectomy. (Trial registration number (TRN) with Clinical Trials Registry-India CTRI: REF/2024/01/078456 and date of registration: 29/01/2024; Retrospectively registered)
The relationship between homocysteine and chronic obstructive pulmonary disease: Results from NHANES 2001-2006 and mendelian randomization Study
Authors: Xu Zhilong , Zeng Ao , Yin Yanze , Chen Keyi , Wang Chao , Fang Xinyun , Abuduwayiti Abudumijiti , Wang Jiarui , Jiang Gening , Dai Jie 
Published: January 2024

Abstract
We analyzed the relationship between homocysteine concentration in blood and chronic obstructive pulmonary disease (COPD) and related dyspnea by using the data from National Health and Nutrition Examination Survey (NHANES) database and Mendel Randomization (MR), and found that the increase of cysteine concentration will promote the occurrence of COPD dyspnea.
What is known about ——this topic-sufficient sample size or Mendelian randomized analysis can well determine the relevant causal relationship.
Summarize the impact of this study——in the past few years, some studies have recognized the relationship between cysteine level and acute exacerbation of COPD, but these studies have a small sample size and are not authoritative enough.
What does this study add——the level of cysteine in blood may be affected by the number of smoking and drinking.
Influence of Nano POFA Towards Production of Self-Consolidating High-Strength Concrete (SCHSC)
Authors: Halim Nuradila I. , Newman Aidan , Sidek Muhd Norhasri Muhd , Saman Hamidah Mohd 
Published: January 2024

Abstract

The applicability of green concrete in the construction industry makes it a favoured topic among researchers in many countries, including Malaysia. The development of this innovative green concrete is made of waste material as one of its constituents. Palm oil fuel ash (POFA) is one of the agricultural wastes, which is the product of burnt palm oil husk and palm kernel shells in a palm oil mill boiler. POFA negatively impacts the environment and health because it is abundantly disposed of in landfills without any commercial value. This paper reviews the potential and innovative incorporation of grinding POFA into concrete as a cement replacement to make it more sustainable. This research highlighted the influence of Nano-POFA (NaPOFA) on the production of Self Consolidating High-Strength Concrete (SCHSC) through an experimental study. NaPOFA is prepared using high-energy milling and introduced as cement replacement from 1–10%. The evaluation of NaPOFA is divided into four categories: physical properties using a particle size analyser, fresh properties using a flow table test, mechanical properties using a compressive strength test, and supported using microscope imaging.
MAPPING: Debiasing Graph Neural Networks for Fair Node Classification with Limited Sensitive Information Leakage
Authors: Song Ying , Palanisamy Balaji 
Published: January 2024

Abstract

Despite remarkable success in diverse web-based applications, Graph Neural Networks(GNNs) inherit and further exacerbate historical discrimination and social stereotypes, which critically hinder their deployments in high-stake domains such as online clinical diagnosis, financial crediting, etc. However, existing research in fair graph learning typically favors pairwise constraints to achieve fairness but fails to cast off dimensional limitations and generalize them into multiple sensitive attributes; besides, most studies focus on in-processing techniques to enforce and calibrate fairness, constructing a model-agnostic debiasing GNN framework at the pre-processing stage to prevent downstream misuses and improve training reliability is still largely under-explored. Furthermore, previous work tends to enhance either fairness or privacy individually but few probes into how fairness issues trigger privacy concerns and whether such concerns can be alleviated with fairness intervention. In this paper, we propose a novel model-agnostic debiasing framework named MAPPING (\underline{M}asking \underline{A}nd \underline{P}runing and Message-\underline{P}assing train\underline{ING}) for fair node classification, in which we adopt the distance covariance($dCov$)-based fairness constraints to simultaneously reduce feature and topology biases under multiple sensitive memberships, and combine them with adversarial debiasing to confine the risks of sensitive attribute inference. Experiments on real-world datasets with different GNN variants demonstrate the effectiveness and flexibility of MAPPING. Our results show that MAPPING can achieve better trade-offs between utility and fairness, and mitigate privacy risks of sensitive information leakage.