bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors and survival outcomes in children with early cardiotoxicity after allogeneic hematopoietic stem cell transplantation
Authors: dou ying , Tong Ke , Meng Yan , Zhang lu , Lei xiao , Liu Qihui , Guan Xianmin , Yu Jie 
Published: December 2023

Abstract
We conducted a retrospective single-center study of pediatric patients who underwent allogeneic hematopoietic stem cell transplantation (allo-HSCT) between January 2016 and December 2022 at the Children's Hospital Affiliated with Chongqing Medical University to evaluate the clinical characteristics of early cardiac events (ECEs) after allo-HSCT and its impact on survival outcome. We enrolled 444 patients who underwent allo-HSCT—304 males (68%) and 140 females (32%)—with a median age of 3.3 years (1.8-6.5 years) at transplantation. We found that 73 patients (16.4%) had ECEs after allo-HSCT. The ECEs included valvular disease (n=46), pericardial effusion (n=38), arrhythmia (n=9), heart failure (n=16), and dilated cardiomyopathy (n=1). Female sex, age ≥ 6 years, body mass index (BMI) < 16 kg/m2 and HLA-type mismatches were risk factors for ECEs. We designed a stratified cardiac risk score that included these risk factors, and the higher the score was, the greater the cumulative incidence of ECEs. The occurrence of an ECE had a significant negative effect on overall survival (OS) rates after allo-HSCT. In addition, stratified analysis based on the number of combined ECEs showed that the greater the number of combined ECEs, the more significant was the negative impact on OS rates.
Newborn Care Service Utilization and Associated Factors among Women who gave birth in Kore District, West Arsi Zone, Ethiopia, 2022. A mixed method study
Authors: Guye Ararso Hordofa , Lata Bekele Niguse , Banti Tomas , Nigussie Tadesse , Meka Beka Teressa 
Published: December 2023

Abstract

Background: Community-based newborn care is a national initiative that brings life-saving care to mothers and newborns in Ethiopian communities by integrating a newborn care program into the continuum of maternal and child health care by improving community participation to reduce child morbidity and mortality, and it promotes healthy growth and development.
Objective:To assess newborn care service utilization and associated factors among women who gave birth in Kore District, West Arsi Zone, Ethiopia 2022.
Methods:A community-based cross-sectional study design supplemented with a qualitative study approach was implemented from January 02 to February 10, 2022, with a total sample size of 560. Data collection was done by using a structured interviewer-administered questionnaire using simple random sampling techniques to select mothers with their neonates from the selected kebeles. For qualitative findings, a focus group discussion guide was used to supplement the quantitative findings. Data were entered into Epi-info version 7.2 and exported to SPSS version 25 for analysis. Binary logistic regression analysis was used to declare the statistical significance of the variables with community-based newborn care services utilization with an adjusted odds ratio with a 95% confidence interval at p-value ≤ 0.05.
Result:In this study, the prevalence of community-based newborn care service utilization among women who gave birth was 45.3 % with a 95% CI of (41.2, 49.6). The mean age of the participants was 29.32 (±6 SD) years and their age ranged from 18 to 61 years. Of all assessed factors;knowledge of community-based newborn care service (AOR= 2.16, 95% CI: 1.34-3.51), attended PNC follow-up (AOR=3.27, 95% CI: 1.67-1.72), closed health post (AOR= 0.50, 95% CI: 0.31-0.82) and distance from a health facility (AOR= 2.63, 95% CI: 1.09-5.44) were significantly associated with community-based newborn care service utilization. The qualitative finding revealed that; having sufficient knowledge about community-based newborn care, closed health posts; cultural beliefs, and the distance from health facilities were the key factors for community-based newborn care service utilization.
Conclusion:The study revealed that, community-based newborn care service utilization was low, which is only 45.3% of participants utilized community-based newborn care services. The study identified that having knowledge of community-based newborn care service, attended PNC follow-up, closed health posts and less distance from health facilities were significantly associated with community-based newborn care service utilization. Thus, the district health office and concerned stakeholders should work on community-based newborn care service utilization by strengthening child care service delivery and improving community awareness of newborn care service at the community level.
Association between alcohol consumption characteristics and anxiety : A gender perspective for Korean adults
Authors: Kim Joo O , Park Gyu Nam , Oh Jae Won , Lee San 
Published: December 2023

Abstract

Background
Studies have examined the association of alcohol consumption characteristics with depression, but few studies explored their association with anxiety. This study investigated the association of alcohol consumption characteristics such as drinking frequency, drinks per occasion, and alcohol flushing with anxiety in South Korea.
Methods
Using data from the 2021 Korea National Health and Nutrition Examination Survey (3509 participants aged 19 years and older), we identified alcohol flushing in individuals when their faces turned red after one glass of beer. Drinking frequency and drinks per occasion were categorized by the Korean Alcohol Guidelines. The Generalized Anxiety Disorder − 7 score of 5 or more indicated anxiety. A multivariable logistic regression performed separately by gender determined the relationship between alcohol consumption and anxiety.
Results
Alcohol flushing and anxiety symptoms were found associated only for women drinkers (Odd Ratio (OR):1.30, 95% Confidence Interval (CI):1.00–1.69, p = 0.047). Women consuming ≥ 3 drinks per occasion showed higher anxiety symptoms than light drinkers (OR: 1.38, 95% CI: 1.06–1.79, p = 0.017). Both men and women who consumed alcohol more than four times a week showed increased odds of anxiety symptoms (OR: 1.87, 95% CI: 1.23–2.84, p = 0.003; OR: 2.42, 95% CI: 1.32–4.43, p = 0.004, respectively).
Conclusion
The study found key drinking characteristics such as alcohol flushing and drinks per occasion associated with anxiety symptoms only for women, emphasizing the need for tailoring anxiety detection and prevention by gender and drinking pattern.
The Nexus between Access to Agricultural Extension Services and Adoption of Sustainable Soil Conservation Practices in Limu Districts, Oromia, Ethiopia
Authors: Kerorsa Gemechu Mulatu 
Published: December 2023

Abstract
Provision of agricultural extension service is the primary mechanism that increases smallholder farmer’s adoption of sustainable soil conservation practices. This study was, therefore, attempted to examine the nexus between access to agricultural extension services and the adoption of sustainable soil conservation practices in western oromia in the case Limu districts. Data was collected from both primary and secondary data sources. Primary data was collected using a structured questionnaire collected from 771 sample respondents. Descriptive, inferential, and seemingly unrelated bivariate probit regressions (SUBPR) were used for data analysis. The results of the SUBPR indicated that sex of household head, educational attainment of household head, credit, access to information and income were among the common underlying factors affecting access to agricultural extension services and adoption of sustainable soil conservation practices in Limu districts. Therefore, government should strengthen rural credit institutions, dissemination of information, and infrastructural development issues were some of the areas that should be considered.
The recently compiled strong motion databank of Iran
Authors: Shokouhirad Sahar , Ansari Anooshiravan , Ghafory-Ashtiany Mohsen 
Published: December 2023

Abstract

This paper presents a comprehensive and integrated databank of the Iranian strong ground motions that occurred from 1973 to 2018. The databank consists of 7196 three-component acceleration records from 3180 earthquakes and 1157 stations in Iran. In this paper, the characteristics of the Iranian strong ground motion data are presented in terms of event, station, and recording distributions. The events are characterized by magnitude in the range 2.4–7.7. Shear wave velocity has been measured and reported at 603 strong motion stations of the databank. In this study, three different empirical techniques are applied to classify the stations. A new method is proposed for site classification based on the correlation coefficient between the horizontal-to-vertical (H/V) response spectral ratios of the ground motion records recorded by each station. It is noticeable that the raw accelerograms have been uniformly processed in the entire databank using the filtering and wavelet de-noising methods to remove high- and low-frequency noise. Moreover, by comparison between the Fourier Amplitude Spectrum (FAS) of the noises detected in all acceleration and velocity time series by the filtering and the wavelet de-noising methods, it was determined that the mean and mode of FAS of the noises detected by the wavelet de-noising method in most of the frequencies is higher than mean and mode of FAS of the noises detected by the filtering method.
Hydrastinine and β-sitosterol Synergistically Target Acute Myelocytic Leukemia in a Ferroptosis-Related Prognostic Model
Authors: Yang Shuyao , Lin Xiangbo , Shi Bo , Meng Jiaqi , Liu Liang , Yan Lina , Xie Fang 
Published: December 2023

Abstract
Acute myeloid leukemia (AML) is a malignant tumor with a high incidence and poor prognosis. Ferroptosis plays a crucial role in regulating carcinogenesis and tumor progression. However, a combination therapy of traditional Chinese medicine and western medicine targeting AML using a ferroptosis-related prognostic model is lacking. Herein, β-sitosterol and hydrastinine were shown to exert a significant synergistic effect on AML. First, prognostic genes associated with ferroptosis were evaluated and the prognosis model was obtained by bioinformatics. Second, the results of immune infiltration analysis showed that the abundances of B cells, macrophages, T cells and monocytes were significantly different between the high- and low-risk groups. Notably, these genes were associated with 296 drugs in the CellMiner database. Network pharmacology and molecular docking analyses showed that β-sitosterol, the active ingredient in Tripterygium wilfordii, targeted oncogenes, CAS9 and PON1. Combinatorial experiments further supported that hydrastinine and β-sitosterol significantly inhibited the growth of AML cells and improved the drug sensitivity of AML cells to ferroptosis inducers. In conclusion, our findings provide a potential strategy for the combined treatment of AML for integrative medicine.
Comparative Analysis of Sands for Concrete Making: Case Study of River Sand, White Sand and Crushed Sand in Kinshasa, DR Congo
Authors: MUFUNGIZI Innocent , MABA Christopher , AWADHIFO Alain 
Published: December 2023

Abstract
Background: Urbanization is one of the keys to development. Population growth and rural exodus are putting pressure on demand for social housing. The city of Kinshasa, being a megalopolis, faces this strong demand in the construction sector. Unfortunately, several problems arise, notably non-compliance with standards, haphazard construction and limited knowledge of the properties of the materials available.
Methods: With the aim of making a contribution to the choice of materials, this work is based on the physical properties of sands including Congo River sand, white sand and crushed sand and their impacts on the compressive strength of the concretes made using these sands. To do this, we sampled 70kg of each type of sand that we used in the laboratory for the physical identification tests of the sands, then we made the concretes to finally move on to the mechanical tests.
Results: The compressive strength of concrete made from river sand recorded a value of 23.3 N/mm2 at 7 days, then increased to 26.2 N/mm2 at 14 days, finally reaching 29.7 N/mm2 at 28 days. For white sand, the variation in the compressive strength of concrete is very small, it goes from 21 N/mm2 at 7 days, to 21.3 N/mm2 at 14 days, then to 21.5 N/mm2 at 28 days. Finally, the variation in the breaking stress of concrete made from crushed sand is 15.5 N/mm2 at 7 days, 16.05 N/mm2 at 14 days, and 18.05 N/mm2 at 28 days.
Conclusion: Congo River sand has the best physical properties. Concrete made from this sand has the best compressive strength. It therefore becomes the best type of sand to use for making concrete. Crushed sand presents poor performance due to its physical properties and requires reinforcement techniques to use it in the manufacture of concrete.
Ensemble rainfall–runoff modeling of physically based semi-distributed models using multi-source rainfall data fusion
Authors: Gichamo Tagesse , Nourani Vahid , Gökçekuş Hüseyin , Gelete Gebre 
Published: December 2023

Abstract

This study was aimed at ensemble rainfall–runoff modeling by Soil and Water Analysis Tool (SWAT), the Hydrologic Engineering Center's Hydraulic Modeling System, and Hydrologiska Byråns Vattenbalansavdelning of Gilgel-Abay watershed, Blue Nile basin, Ethiopia. For modeling, daily rainfall datasets of five gauges and three satellites, streamflow, and spatial data were used. In the modeling stage, first, the runoff was simulated separately using the rainfall data of gauges, satellites, and their fusion. Second, ensemble rainfall–runoff simulation of the rainfall dataset fusion-based runoff result was conducted via the proposed weighted average, simple average, and neural network (NNE) ensemble techniques. The results exhibited that all models are good in capturing the rainfall–runoff relationship; however, SWAT showed slight superiority by Nash–Sutcliffe efficiency of 0.807 and 0.821 for gauge and fusion data, respectively. The rainfall fusion ensemble model revealed significant improvement over modeling by satellite rainfall owing to the bias-correcting gauge rainfall over satellite rainfall. The NNE technique enhanced the efficiency of the low-performing satellite-rainfall-based model by 17.5% and the rainfall fusion-based model by 13.3% at the validation stage. In general, the result of this study points out that the rainfall datasets’ fusion from multi-sources would be worthy for the rainfall–runoff simulation of ungauged basins.
Consequence assessment of the La Giang dike breach in the Ca River system, Vietnam
Authors: Tran Chau Kim , Nguyen Thai Canh 
Published: December 2023

Abstract

Ca River is one of the largest rivers in Vietnam. The river provides water, electricity, and navigation for millions of people living along the banks. Besides these great benefits, the river also poses many potential risks for people. In the case of flooding, this river can cause terrible damage, especially in the case of dike breach. Therefore, this article, by combining a field survey and mathematical simulation, has been conducted to present the results of the dike breach for the La Giang dike of Ca river, in Ha Tinh province, Vietnam. Via the field survey, potential dike breach locations were specifically identified, which helps minimize the number of calculation scenarios. The mathematical model was calibrated and validated with large floods in the area. The results from the mathematical model show that the model is consistent with the observation data, with the Nash index at good to very good levels. Based on the data, a series of simulations was performed to assess the dike breach consequences. In each case, the study provided details on the inundation area, the number of affected residents and the length of flooded road for each inundation level by administrative unit. Based on the calculated results, the degree and scope of consequence varied depending on the locations of the dike breach. The results of the study are the foundation for the building of a local database of flood and storm control. This is very useful information for the decision-makers to establish different response plans for different emergency cases.
Amalgamation of Transfer Learning and Explainable AI for Internet of
Medical Things
Authors: Murugan Ramalingam , Paliwal Manish , Lakshmi Patibandla Rama Seetha Maha , Shah Pooja , Balaga Tarakeswara Rao , Gurrammagari Deepti Raj , Singaravelu Parvathavarthini , Yenduri Gokul , Jhaveri Rutvij 
Published: December 2023

Abstract:
The Internet of Medical Things (IoMT), a growing field, involves the interconnection of medical devices and data sources. It connects smart devices with data and optimizes patient data with real time insights and personalized solutions. It is mandatory to hold the development of IoMT and join the evolution of healthcare. This integration of Transfer Learning
and Explainable AI for IoMT is considered to be an essential advancement in healthcare. By
making use of knowledge transfer between medical domains, Transfer Learning enhances diagnostic accuracy while reducing data necessities. This makes IoMT applications more efficient which is considered to be a mandate in today’s healthcare. In addition, explainable AI
techniques offer transparency and interpretability to AI driven medical decisions. This can foster trust among healthcare professionals and patients. This integration empowers personalized
medicine, supports clinical decision making, and confirms the responsible handling of sensitive
patient data. Therefore, this integration promises to revolutionize healthcare by merging the
strengths of AI driven insights with the requirement for understandable, trustworthy, and
adaptable systems in the IoMT ecosystem.
Experimental Determination of the Bearing Capacity of a Reinforced Concrete Floor Slab
Authors: Masalov A. V. , Filatov Yu. B. 
Published: December 2023

Purpose of research. Experimental determination and analysis of the bearing capacity, deformability and crack resistance of a reinforced concrete floor slab supported on three sidesMethods. Testing a specimen of a reinforced concrete floor slab supported on three sides (loggia floor) by a controlled load simulating the operational one. Measurement of deflections. Analysis and justification of test resultsResults. The slab was loaded to a level of 325 kN or 20.1 kPa. This load exceeded the control load by a factor of 1.64 with a safety factor of 1.6, exceeded the design load by a factor of 2.64, and exceeded the standard load by a factor of 3.08. The maximum recorded deflection at maximum load was 3.01 mm in or in span fractions of 0.0009, which is 7.41 times less than the allowable deflection from the standard load - 0.00667 of the span length. The testing has been terminated for safety reasons.Conclusion. The points that could allow the developing of more economical building structures are: refinement of the design scheme for the operation of structures, the optimal choice of a finite element in the calculation, as well as the gradual inclusion in the sets of rules of methods for calculating building structures based on the theory of structural systems with distributed parameters at critical energy levels.
Compound Molecules of Network Pharmacology-Based of Tamarillo (Cyphomandra betacea Cav.) and the Potential as Noodle for Type 2 Diabetes Mellitus Treatment
Authors: Fitriyani Fitriyani , Ningrum Salsabila E.S. , Mutiah Rohiatul , Kinasih Larasati Sekar 
Published: December 2023

Consuming noodles excessively is not good for health because it contains high trans fat, which can cause diabetes mellitus (DM) as a disease with a high prevalence, especially type 2 DM, as much as 95% in Indonesia. Tamarillo (Chypomandra betacea Cav.) can potentially reduce blood glucose levels and restore adipokine regulation to prevent insulin resistance in type 2 DM. This study aims to determine the formulation and potential of tamarillo compounds into noodle products named "Chypotes (Chypomandra Antidiabetes) Noodle" as an alternative food for type 2 DM patients. The methods used are noodle formulation, organoleptic test, hedonic test, and network pharmacology. Based on the results of an organoleptic test, Chypotes Noodle has a chewy texture, a distinctive smell, yellow colour, and a slightly sour tasteless taste typical of Tamarillo. Based on the results of the hedonic test, 30 respondents chose the like and very like options in filling out the questionnaire with a percentage of 80-90%. Based on the Network Pharmacology of Tamarillo shows that 150 of the 365 target proteins of Tamarillo are involved in the biological processes and signaling pathways of type 2 diabetes mellitus, with 75 target proteins locking and interacting. Compound Molecules of Tamarillo, such as six bioactive components of the hydroxycinnamic acids group, have activity in type 2 DM and affect the biological processes and signaling pathways of type 2 DM against ADIPOQ, TNF, and INS. Therefore, Tamarillo can potentially be used as an alternative food product in the form of noodles for type 2 DM treatment.
Klaipėdos krašto oikonimų <i>Jan Alzeik, andulen / Greger Zceyp, Wittblind</i> kilmė
Authors: Kregždys Rolandas 
Published: December 2023

Straipsnyje detalizuojami Klaipėdos krašto, t. y. Mažosios Lietuvos šiaurinės dalies palei Nemuno žemupį ir Baltijos jūrą, oikonimų Jan Alzeik, Andullen / Greger Zceyp, Wittblind formaliosios pateikties ypatumai bei pateikiama šių toponimų etimologinė analizė.
Pengaruh Pendidikan Kesehatan ASI Eksklusif terhadap Breastfeeding Self-Efficacy pada Ibu Menyusui
Authors: Widayanti Arief , Mawardika Tina 
Published: December 2023

Breast milk (ASI) is the optimal nutrition for infants compared to formula milk. One key factor in the success of exclusive breastfeeding is Breastfeeding Self-Efficacy (BSE), which can be enhanced through health education. This study aims to determine the impact of health education on exclusive breastfeeding on breastfeeding self-efficacy. The research employed a quasi-experimental design with a nonequivalent (pretest and posttest) control group approach. The sample comprised breastfeeding mothers with infants aged 0 to 2 years, totaling 34 respondents divided into intervention and control groups. Purposive sampling was utilized for sample selection. The instrument employed was the Breastfeeding Self-Efficacy Scale Short Form (BSES-SF). Bivariate analysis was conducted using an independent t-test to examine whether there were differences in breastfeeding self-efficacy between the intervention and control groups. Results showed a significant p-value (0.000) < α (0.05), indicating an influence of exclusive breastfeeding health education on breastfeeding self-efficacy among breastfeeding mothers.
Abstrak
Air Susu Ibu (ASI) merupakan nutrisi terbaik bagi bayi dibandingkan dengan susu formula. Salah satu faktor keberhasilan pemberian ASI eksklusif adalah Breastfeeding Self- Efficacy (BSE). BSE bisa ditingkatkan dengan pemberian pendidikan kesehatan. Penelitian ini bertujuan untuk mengetahui pengaruh pemberian pendidikan kesehatan tentang ASI eksklusif terhadap breastfeeding self-efficacy. Metode penelitian menggunakan quasy experimental dengan pendekatan nonequivalent (pretest and posttest) with control group design. Sampel dalam penelitian ini adalah ibu menyusui bayi berusia dari 0 bulan sampai dengan 2 tahun yaitu sebanyak 34 responden yang terbagi atas kelompok intervensi & kelompok kontrol. Teknik pengambilan sampel pada penelitian ini menggunakan purposive sampling. Instrument yang digunakan adalah kuesioner breastfeeding self-efficacy scale short form (BSES-SF). Analisa bivariat menggunakan uji independent t test. Berdasarkan hasil penelitian didapatkan nilai signifikasi p value (0,000) < α (0,05) yang berarti ada pengaruh pemberian pendidikan kesehatan tentang ASI eksklusif terhadap breastfeeding self-efficacy pada ibu menyusui.