bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hepatic steatosis after pancreatectomy: Does duodenum preservation mitigate the risk?
Authors: L Harilal S , Azam Mohamed Bilal , Pottakkat Biju , Raja Kalayarasan , VC Sunita , Mohan Pazhanivel 
Published: January 2024

Abstract
Background: Hepatic steatosis is a potential cause of long-term morbidity in 20-40% of post-pancreatectomy patients. Various risk factors have been proposed for hepatic steatosis after pancreatectomy. The present study aims to compare the incidence of post-pancreatectomy hepatic steatosis in patients with and without duodenum-preserving surgeries.
Methods: A prospective cohort study of patients who underwent pancreatectomy with or without duodenum preservation for benign and malignant pancreatic diseases between January 2019 and December 2022 was included. Patients who underwent distal and total pancreatectomy were excluded. CT criteria for hepatic steatosis were absolute liver attenuation of less than 40 Hounsfield units (HU) or the difference between mean splenic and liver attenuation of more than 10 HU. Demographic parameters, exocrine insufficiency, and hepatic steatosis in post-operative periods were compared between the two groups.
Results: 40 patients who underwent PD for malignant or non-malignant diseases were compared with 40 who underwent duodenal preserving pancreatic head resection (DPPHR) for chronic pancreatitis. Around 35% of patients had post-operative exocrine pancreatic enzyme insufficiency (EPI) in the DPPHR group, and 15% had EPI in the PD group. The incidence of hepatic steatosis after a minimum follow-up after six months was 17.5% (7/40) in the DPPHR group and 37.5% (15/40) in the PD group. Duodenal resection was found to be a significant risk factor for developing hepatic steatosis (P-0.045), which also persisted after propensity score matching analysis.
Conclusion: Duodenal resection surgeries have more association with hepatic steatosis compared to duodenal preserving pancreatic surgeries.
Effect of habituation and gene silencing on blood biochemical traits in local chicken indicative of their level of welfare
Authors: Mahmood O. K. , Abdulateef Salwan M. , Alnori H. M. , Tatar A. 
Published: January 2024

Abstract

Chickens respond to the signals of other chickens, and as the signals are repeated, the chicken's reactions adapt over time. In studies of chickens responding to repeated playbacks of recorded chicken signals, the word "habituation" has been used to describe both overt behaviours and behavioural responses during specific tests in both field and laboratory settings. Gene silencing, on the other hand, is the regulation of gene expression in a cell that inhibits a particular gene from expressing. The current study aimed to reduce the stress responses of a breed of local chickens by changing their behavioural or genetic factors, and assessed blood traits that reflect their level of welfare. The study used 120 hen chickens obtained at 22 weeks old, divided into six treatments, with four replicates for each treatment (20 chicks per treatment, 5 chicks per replicate) as follows: T1 was a negative control treatment consisting of a local Iraqi chicken breed; T2 was a positive control treatment consisting of a commercial breed of chickens; T3 involved the local breed with siRNA used to silence the corticosterone hormone pathway to the CYP11B2 and CYP11B1 genes by injection in the jugular vein at the age of 24 and 40 weeks; T4 consisted of mixed groups with 25% commercial chicken + 75% local chicks; whilst T5 consisted of 50% commercial chicken + 50% local chicken; and T6 consisted of 75% commercial chicken + 25% local chicken. The results showed a significant improvement (P≤0.05) in Glucose, Cholesterol, Total Protein, LDL, HDL, Globulin and Albumin for T3 and T5 compared with the other treatments; and a significant improvement (P≤0.05) in blood corticosterone in T3 immediately after the injection and two weeks later. The results show that there is an effect of habituation and gene silencing on blood traits, indicating an improved level of welfare for the T3 and T5 chickens.
Bi-parameter pseudo-differential operators in bi-parameter Triebel-Lizorkin and Besov Spaces
Authors: Huang Liang , Zhang Yaming 
Published: January 2024

Abstract
In this paper, we mainly establish the $F^{(s_1,s_2)}_{p,q}(\mathbb{R}^{n_1}\times\mathbb{R}^{n_2})$ and $B^{(s_1,s_2)}_{p,q}(\mathbb{R}^{n_1}\times\mathbb{R}^{n_2})$ boundedness of the bi-parameter pseudo-differential operator, where the symbol involved is given by the standard symbols of the H\"{o}rmander class $BS^{(m_1,m_2)}_{(1,1),(\delta_1,\delta_2)}(\mathbb{R}^{2n_1}\times\mathbb{R}^{2n_2})$ for $-\infty
Mathematics Subject Classification 42B15, 42B25.
High-flux, ultraviolet-to-visible-tunable, ultrafast light source based on gas-filled capillary fibre system
Authors: Huang Zhiyuan , Liu Donghan , Pan Jinyu , Wang Xinliang , Chen Tiandao , Yu Yue , Chang Xinshuo , Jiang Xin , Pang Meng , Leng Yuxin , Li Ruxin 
Published: January 2024

Abstract
Ultrafast light sources with broadband wavelength tunability, as useful tools for studying ultrafast phenomena and light-matter interactions, have attracted extensive interests in recent several decades. High-performance ultrafast pulse generation with simultaneously high pulse repetition rate, high photon flux, and broad wavelength-tuning range covering deep ultraviolet to visible has, however, proven difficult to realize. Here, we demonstrate that through cascading two nonlinear pulse compression stages (one is based on a multi-pass-cell cavity and the other based on a 1-m length of hollow capillary fibre), high-repetition-rate pulses from an industrial-grade high-power picosecond laser can be efficiently compressed to ~15 fs durations, giving rise to an ultrahigh compression ratio of ~74. The generated few-cycle optical pulses, exhibiting excellent beam quality and stability, were used in our set-up to drive the high-efficiency dispersive-wave-emission process in another 1-m length of gas-filled capillary fibre, delivering few-cycle short-wavelength pulses with μJ-level pulse energy, 25 kHz/100 kHz pulse repetition rate, >1016 phs/s photon flux and continuous wavelength-tuning ability from 200 nm to 700 nm. The table-top ultrafast laser system, featuring broad wavelength coverage, may have many potential applications in advanced spectroscopy and ultrafast-optics experiments.
Assessment of Water Quality of Otamiri River Along Selected Reach Using Drone Technology
Authors: Nmecha Engr. , Okereke C. D. , Egwuonwu Chukwudi , Okorafor Okore 
Published: January 2024

Abstract
research work focuses on the study of water quality in the Otamiri River in Imo State, Nigeria. It highlights the concerns about pollution due to anthropogenic and industrial activities, the need for innovative monitoring methods like drone technology, and the global challenges in water quality. The study emphasizes the implications for public health and environmental policies, aiming to assess and monitor the distribution of contaminants along the river using drones, and compare these findings with laboratory analyses. This approach is seen as a transformative step in water management practices, contributing to international knowledge in water quality management. The document also discusses the integration of drone technology in environmental monitoring to bridge local challenges with global solutions.
Removal of tellurium(IV) from environmental aquatic systems using metal-organic framework material MIL-100(Fe)
Authors: Huang Yiru , Li Youyou , Zhong Qingwei , Luo Chen 
Published: January 2024

Abstract

Metal-organic framework (MOF) materials, characterized by their porosity and large specific surface areas, exhibit excellent adsorption properties. With the aim of removing Te(IV) from environmental aquatic systems, this study is the first to propose the use of MIL-100(Fe). The material reveals a strong adsorption capacity for Te(IV), with maximum adsorption of 531.9 mg/g, superior to other adsorbent materials. Adsorption isotherm and kinetic models indicate that the adsorption process primarily involves monolayer chemical adsorption. According to the thermodynamic parameters, the adsorption reaction is endothermic. The experiment individually examined factors affecting the material's adsorption performance, including adsorbent dose, initial concentration of Te(IV), pH, adsorption time, and coexisting ions. Even under high ion strength conditions and high concentrations of coexisting ions, the material's adsorption efficiency for Te(IV) still reached over 94%. The material has been successfully applied to remove Te(IV) from lake water, river water, and seawater, yielding satisfactory results. Due to the high salinity and ionic strength of the solution, the removal efficiency of Te(IV) in the seawater matrix was slightly lower than that in freshwater (river and lake water). Thus, this material shows promise for the removal of Te(IV) from complex aquatic systems.
Microwave-assisted Natural Gums for Drug Delivery Systems: Recent
Progresses and Advances over Emerging Biopolymers and Technologies
Authors: Matini Amir , Naghib Seyed Morteza 
Published: January 2024

Abstract:
Natural polymers play a crucial role in a wide range of industries, allowing
for extensive conjugation with a variety of materials and components to produce a vast
multitude of products. Biomaterials have been extensively studied due to their application potential in pharmaceutical formulation development, tissue engineering, and
biomedical fields. Despite this, many natural gums in their natural state have limitations
in terms of microbial contamination, susceptibility, solubility, and stability. To surmount these limitations, chemical or physical modifications are made to the polymer to
tailor its properties to particular applications. These polymer modifications integrate traditional elements of materials science, physics, biology, chemistry, medicine, and engineering. Microwave irradiation has become an established method for accelerating and
facilitating chemical modification reactions over the past several decades. This method
allows for the efficient execution of synthesis protocols by providing precise temperature and voltage control. In addition, microwave irradiation contributes to sustainable
and environmentally friendly chemistry principles. This article highlights the importance of microwave-assisted natural gum modification in the production of novel dosage
forms.
Recent Advances in Molecular Imprinting for Proteins on Magnetic Microspheres
Authors: Zhang Jing , Yuan Shujie , Beng Shujuan , Luo Wenhui , Wang Xiaoqun , Wang Lei , Peng Can 
Published: January 2024

Abstract:
The separation of proteins in biological samples plays an essential role in the development
of disease detection, drug discovery, and biological analysis. Protein imprinted polymers
(PIPs) serve as a tool to capture target proteins specifically and selectively from complex media
for separation purposes. Whereas conventional molecularly imprinted polymer is time-consuming
in terms of incubation studies and solvent removal, magnetic particles are introduced using their
magnetic properties for sedimentation and separation, resulting in saving extraction and centrifugation
steps. Magnetic protein imprinted polymers (MPIPs), which combine molecularly imprinting
materials with magnetic properties, have emerged as a new area of research hotspot. This review
provides an overview of MPIPs for proteins, including synthesis, preparation strategies, and applications.
Moreover, it also looks forward to the future directions for research in this emerging field.
Nitrogen-fused Heterocycles: Empowering Anticancer Drug Discovery
Authors: Biswas Tanya , Mittal Ravi Kumar , Sharma Vikram , Kanupriya  , Mishra Isha 
Published: January 2024

Abstract:
The worldwide impact of cancer is further compounded by the constraints of current
anticancer medications, which frequently exhibit a lack of selectivity, raise safety apprehensions,
result in significant adverse reactions, and encounter resistance mechanisms. The current situation
highlights the pressing need to develop novel and more precise anticancer agents that prioritize
safety and target specificity. Remarkably, more than 85% of drugs with physiological activity contain
heterocyclic structures or at least one heteroatom. Nitrogen-containing heterocycles hold a
significant position among these compounds, emerging as the most prevalent framework within the
realm of heterocyclic chemistry. This article explores the medicinal chemistry behind these molecules,
highlighting their potential as game-changing possibilities for anticancer medication development.
The analysis highlights the inherent structural variety in nitrogen-containing heterocycles,
revealing their potential to be customized for creating personalized anticancer medications. It also
emphasizes the importance of computational techniques and studies on the relationships between
structure and activity, providing a road map for rational medication design and optimization. Nitrogen-
containing heterocycles are a promising new area of study in the fight against cancer, and this
review summarises the state of the field so far. By utilizing their inherent characteristics and exploiting
cooperative scientific investigations, these heterocyclic substances exhibit potential at the
forefront of pioneering therapeutic approaches in combating the multifaceted obstacles posed by
cancer.
Investigation of The Effect of Metal-based Medicine Arsenicum album on Humoral Immune Response in SRBC-immunized Mice
Authors: Behera Sangita , Sharma Mahima , Lal Roshan , Regar Raj Kumar , Tripathi Deepika , Gupta Pankaj , Kumar Godlaveti Vijay Narasimha , Verma Digvijay , Kaushik Subhash , Khurana Anil 
Published: January 2024

Background:
In complementary and alternative medicinal systems, the Arsenicum
album in ultra-high dilution was used in various therapeutic conditions, considering its effects
on the body’s immune system, including the COVID-19 pandemic. However, scientific evidence
regarding its immunomodulatory effects is insufficient.

Objective:
The current study aimed to investigate the immunomodulatory effects of Arsenicum
album in an experimental mouse model.

Materials and Methods:
Immunomodulatory activity of potentized dilutions of Arsenicum album
i.e., 6C, 30C, 200C in BALB/c mice was evaluated by humoral antibody titer and delayedtype
hypersensitivity assays wherein a fixed concentration (0.5 ml of 1× 109 cells/ml) of freshly
prepared sheep RBC was administered as a foreign antigen to generate primary and secondary
antibodies.

Results:
Arsenicum album showed significant immunomodulatory activity by increasing primary
antibody titer evaluated on day 21 of the treatment in all the dilutions as compared to SRBC
and vehicle control group in humoral immune response assay without showing any effect on
delayed-type hypersensitivity.

Conclusion:
The results of this preliminary study indicate that oral administration of Arsenicum
album has the potential to augment primary humoral response at all dilutions. Hence, the possibility
of using the Arsenicum album could be explored to treat immunological conditions, infections,
etc., as an alternative therapy alongwith modern medicines.
Impact of type 2 diabetes mellitus on heart failure with preserved ejection fraction depending on the presence of atrial fibrillation
Authors: Kulaiets N.M. , Kulaiets V.M. , Tkachuk-Hryhorchuk O.O. , Nyshchuk-Oliinyk N.B. 
Published: January 2024

Background. Cardiovascular diseases, including heart failure (HF) and heart failure with preserved ejection fraction (HFpEF), pose a global health challenge. HFpEF is on the rise, especially among the elderly and those with conditions like diabetes, obesity, and hypertension. Type 2 diabetes mellitus (T2DM) often coexists with HFpEF, and atrial fibrillation (AF) further complicates matters due to shared risk factors. The purpose of this study is to comprehensively investigate the influence of type 2 diabetes mellitus on cardiac function and biomarker profiles in patients with heart failure with preserved ejection fraction in the presence or absence of atrial fibrillation. Mate­rials and methods. This was a cohort, single-center study. Four hundred and forty-eight patients with HFpEF were examined. They were divided into 4 groups: group 1 — 189 patients with HFpEF alone; group 2 — 39 patients with HFpEF and T2DM; group 3 — 176 patients with HFpEF and atrial fibrillation; group 4 — 44 patients with HFpEF, AF, T2DM. Results. T2DM may contribute to a slightly older patient population in HFpEF, but age alone is not a primary discriminator. T2DM alone does not substantially impact left ventricular mass index but, when combined with AF, it does. T2DM is associated with an increased left atrial volume index, and AF intensifies this effect. T2DM influences diastolic function, with AF exacerbating it. T2DM affects left ventricular filling pressure, and AF worsens this in HFpEF. T2DM also influences left ventricular systolic function, further compromised when combined with AF in HFpEF patients. Galectin-3 levels are elevated in HFpEF patients with T2DM, further exacerba­ted with AF. NT-proBNP levels are influenced by T2DM and worsened with the combination of AF in HFpEF. SST2 levels are elevated in HFpEF patients with T2DM, further increased with AF, indicating myocardial fibrosis and adverse remodeling. Conclusions. The interaction between T2DM and AF in HFpEF patients creates a synergistic effect, resulting in significant cardiac structural and functional alterations. Novel biomarkers such as galectin-3, NT-proBNP, and sST2 emerge as valuable diagnostic tools, reflecting the complex pathophysiological processes in HFpEF.
Russian History in the Mirror of Heraldry
Authors: Naumov Oleg 
Published: January 2024

In 2022, a team of specialists in the field of special historical disciplines completed the research stage of work on the project of the fundamental generalizing publication "Russian Heraldry: Encyclopedia", which was highly appreciated by the RFBR expert community.
Methodically, the project is based on micro- and macro-historical approaches to the study of the past that are fundamental for modern science. In this case, the micro–level is realized through the analysis of the genesis, iconographic evolution and semantics of the heraldic space, and the macro-historical – through their integration into the context of the main historical events and processes. The heraldic history of the country is presented as a complex, multidimensional process caused by a combination of political, social, cultural and other factors. The encyclopedia is a complete body of knowledge about Russian heraldry, contains articles on the theoretical concepts of this discipline, special terminology, heraldic figures, the history of state, territorial and ancestral coats of arms, the main sources (including material – banners), state institutions, heraldic scientists, artists, etc. The chronological boundaries of the publication are from the end of the XV to the present.
For the first time, a comprehensive encyclopedic study of the history of scientific and practical heraldry of one country (Russia) was undertaken in a broad general historical context, using the latest methods of historical analysis and theoretical experience accumulated by world herbology.
Chuvash Religious Practices: Traditions and Their Transformation (Late 20th – Early 21st Century)
Authors: Yagafova Ekaterina , Petrov Igor 
Published: January 2024

The paper examines modern religious practices of two ethno-confessional groups of the Chuvash — Orthodox and unbaptized, shows the traditional forms of worship and their trans-formation at the turn of the century, determines the compliance of existing practices with the "norms" of the declared religious identity. The study showed that changes in religious prac-tices were manifested in the reduction in number of participants, in the reduction of rituals and the disappearance of a number of elements, in the festivization of the festive and ritual culture, the loss of the original meaning of religious rituals, but at the same time in the growth of activity of the Orthodox Chuvash in the formation of the sacred landscape of their villages and the performance of religious cult. For both groups, there is a discrepancy be-tween confessional identity
and actual religious practices: among the Orthodox — in the form of Orthodox-pagan syncretism and dual faith, among the unbaptized — in the form of elements of Orthodox culture and participation in Orthodox rituals. They are caused by the instability of confessional "borders" due to religious conversion, and the transformation of ritual practices. The study is based on the author's field materials collected in Chuvash vil-lages in the Samara region, the Republics of Bashkortostan and Tatarstan, and the Chuvash Republic.
The Russian Arctic: From Settlements to ‘Colonies’ (Adaptation, Family and Culture)
Authors: Tereshchenko Elena , Fedorov Pavel , Malashenkov Aleksei 
Published: January 2024

In the chosen world, special attention is riveted to the Arctic. Against the backdrop of an overpopulated, overburdened South, conflicts and military clashes occur. The territory of the North and the Arctic is not taken into account as a certain land "reserve" of the planet, where space is still rarefied in that the climate is heavier and harsher. The creation of an environment for human life here, the evolution of this environment, from phenomenal to quite acceptable civilized forms, is the application of the experience of social history, which is very important for understanding the geography of the Russian world, substantiating the status of Russia as an Arctic state.
The purpose of the research project "Russian Arctic: from settlements to "colonies" (adaptation, family, culture)", implemented for three years (2020–2022), was the historical reconstruction of family-related structures that appeared on the Murmansk coast of the Barents seas during the formation of a permanent population in this area (the second half of the 19th – early 20th centuries). Based on the processing of registers of births and other records of the Orthodox population, demographic data were reconstructed and introduced into scientific circulation for the first time, as well as family structures in the form of generational lists of families living in this area, which included information about more than 7 thousand people. The results of the project are summarized in the new scientific publication "Historical and genealogical atlas of the Russian Arctic: Murmansk coast of the Barents Sea (1868–1920)". The publication illustrates the contribution of Russians to the development of the Arctic and is one of the visible evidence of Russia's historical rights to this region of the planet.