bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nutzung von Injektions- und Monitoring-While-Drilling-Daten mit künstlicher Intelligenz zur adaptiven Optimierung von Injektionsmaßnahmen im Tunnelbau (Forschungsprojekt AVANT)
Authors: Wenighofer Robert , Villeneuve Marlène C. , Rathenböck Florian , Maroschek Philipp , Thienert Christian , Klaproth Christoph , Pechhacker Robert , Köneman Frank 
Published: December 2023

ZusammenfassungBeim Tunnelvortrieb wird das Gebirge vor dem Tunnel oft zu Erkundungszwecken oder für vorausauseilende Sicherungsmaßnahmen angebohrt, z. B. zur Injektion von Zementsuspension oder zur Entwässerung. Mittlerweile haben in die Bohr- und Injektionstechnik beim Spezialtiefbau und Tunnelbau digitale Datenaufzeichnungssysteme verbreitet Einzug gehalten. Im Zuge des Projektes AVANT wurden nun Methoden untersucht und entwickelt, um diese Daten bereits Untertage auszuwerten und in den weiteren Bauablauf einfließen zu lassen, anstatt diese bloß für Dokumentationszwecke zu archivieren. Mit dem Ziel modifizierte Ingenieurmodelle für Gebirge und Injektionen abzuleiten sowie für den Aufbau einer injektionsspezifischen Wissensdatenbank wurde untersucht, inwieweit hierfür Methoden der Künstlichen Intelligenz (KI) zweckmäßig zum Einsatz kommen können. Ein Konsortium bestehend aus den deutschen Partnern STUVAe. V., geoteam Ingenieur GmbH und den österreichischen Partnern eguana GmbH, Montanuniverstät Leoben und Züblin Spezialtiefbau Ges.m.b.H. hat kürzlich das Projekt „AVANT – Adaptive Planung von Injektionsmaßnahmen im Tunnelbau mittels Künstlicher Intelligenz“ abgeschlossen, das einige neue interessante Ergebnisse hervorgebracht hat. Der vorliegende Beitrag zeigt auf, wie Bohr- und Injektionsdatensätze unter Anwendung von KI-Methoden zu verwendet werden können, das Gebirge vor der Ortsbrust bzw. den Injektionsmittelbedarf zu prognostizieren, um damit die Baulogistik zu optimieren. Schlussendlich wird ein Vorschlag unterbreitet, wie derartig innovative Ansätze bauvertraglich berücksichtigt werden können.
Restoring microRNA-34a overcomes acquired drug resistance and disease progression in human breast cancer cell lines via suppressing the ABCC1 gene
Authors: Yahya Shaymaa M. M. , Nabih Heba K. , Elsayed Ghada H. , Mohamed Shimaa Ibrahim Abdelmenym , Elfiky Asmaa M. , Salem Sohair M. 
Published: December 2023

Abstract
Purpose
Breast cancer is one of the leading types of cancer diagnosed in women. Despite the improvements in chemotherapeutic cure strategies, drug resistance is still an obstacle leading to disease aggressiveness. The small non-coding RNA molecules, miRNAs, have been implicated recently to be involved as regulators of gene expression through the silencing of mRNA targets that contributed to several cellular processes related to cancer metastasis. Hence, the present study aimed to investigate the beneficial role and mechanism of miRNA-34a-based gene therapy as a novel approach for conquering drug resistance mediated by ATP-binding cassette (ABC) transporters in breast cancer cells, besides exploring the associated invasive behaviors.

Material and Methods
Bioinformatics tools were used to predict miRNA ABC transporter targets by tracking the ABC transporter pathway. After the establishment of drug-resistant breast cancer MCF-7 and MDA-MB-231 sublines, cells were transfected with the mimic or inhibitor of miRNA-34a-5p. The quantitative expression of genes involved in drug resistance was performed by QRT-PCR, and the exact ABC transporter target specification interaction was confirmed by dual-luciferase reporter assay. Furthermore, flow cytometric analysis was utilized to determine the ability of miRNA-34a-treated cells against doxorubicin uptake and accumulation in cell cycle phases. The spreading capability was examined by colony formation, migration, and wound healing assays. The apoptotic activity was estimated as well.

Results
Our findings firstly discovered the mechanism of miRNA-34a-5p restoration as an anti-drug-resistant molecule that highly significantly attenuates the expression of ABCC1 via the direct targeting of its 3′- untranslated regions in resistant breast cancer cell lines, with a significant increase of doxorubicin influx by MDA-MB-231/Dox-resistant cells. Additionally, the current data validated a significant reduction of metastatic potentials upon miRNA-34a-5p upregulation in both types of breast cancer-resistant cells.

Conclusion
The ectopic expression of miRNA-34a ameliorates the acquired drug resistance and the migration properties that may eventually lead to improved clinical strategies and outcomes for breast cancer patients. Additionally, miRNA-34a could be monitored as a diagnostic/prognostic biomarker for resistant conditions.
Improving the effectiveness of video-based flipped classrooms with question-embedding
Authors: Deng Ruiqi , Feng Siqi , Shen Suqin 
Published: December 2023

AbstractAlthough video-based flipped learning is a widely accepted pedagogical strategy, few attempts have been made to explore the design and integration of pre-class instructional videos into in-class activities to improve the effectiveness of flipped classrooms. This study investigated whether question-embedded pre-class videos, together with the opportunity to review these questions at the beginning of in-class sessions, affected student learning processes and outcomes. Seventy university students from two naturally constituted classes participated in the quasi-experimental study. The experiment adopted a pre-test/post-test, between-subjects design and lasted for six weeks, with the same instructional content for the experimental and control groups. Students’ age, sex, pre-experiment motivation, prior knowledge, and perceived knowledge were controlled for in the study. The results indicate that the educational intervention significantly strengthened learning performance, likely due to the increased regularity of engagement with pre-class materials. The intervention did not influence student satisfaction with the pre-class videos or the video viewing duration. Overall, the findings suggest that instructors should consider embedding questions in pre-class videos and reviewing them at the beginning of in-class sessions to facilitate student learning in video-based flipped classrooms.
Wind Turbines and Property Values: A Meta-Regression Analysis
Authors: Schütt Marvin 
Published: December 2023

AbstractA key concern for property owners about the set up of proximate wind turbines is the potential devaluation of their property. However, there is no consensus in the empirical hedonic literature estimating this price-distance relationship. It remains unclear if the proximity to wind turbines reduces, increases, or has no significant effect on property values. This article addresses this ambiguity, combining 720 estimates from 25 hedonic pricing studies in a first comprehensive meta-analysis on this topic. Using Bayesian model averaging techniques and novel publication bias correction methods, I calculate an average of the reported estimates that is free from misspecification and publication bias. In economic terms, I find an average reduction in property values of $$-0.68\%$$

-
0.68
%

for properties 1.89 miles away, which turns to zero beyond 2.8 miles. Next to publication selection, the studies’ ability to control for confounding factors such as pre-existing price differentials and spatial effects explains the variance in reported effect sizes.
Satisfied and High Performing? A Meta-Analysis and Systematic Review of the Correlates of Teachers’ Job Satisfaction
Authors: Wartenberg Gyde , Aldrup Karen , Grund Simon , Klusmann Uta 
Published: December 2023

AbstractJob satisfaction has long been discussed as an important factor determining individual behavior at work. To what extent this relationship is also evident in the teaching profession is especially relevant given the manifold job tasks and tremendous responsibility teachers bear for the development of their students. From a theoretical perspective, teachers’ job satisfaction should be negatively related to turnover intentions and absenteeism, and positively to high-quality teacher-student interactions (i.e., emotional support, classroom management, and instructional support), enhanced student motivation, and achievement. This research synthesis provides a comprehensive overview of the relationship between teachers’ job satisfaction and these variables. A systematic literature search yielded 105 records. Random-effects meta-analyses supported the theoretically postulated relationships between teachers’ job satisfaction and their turnover intentions, absenteeism, teacher-student interactions, and students’ outcomes. Effects were significant not only for teachers’ self-reports of their professional performance, but also for external reports. On the basis of the research synthesis, we discuss theoretical, conceptual, and methodological considerations that inform future research and prospective intervention approaches.
Residual Stresses in Alloy IN718 Produced Through Modulated Laser Powder Bed Fusion
Authors: Georgilas K. , Guo H. , Ahmad B. , Khan R. H. U. , Fitzpatrick M. E. , Kartal M. E. 
Published: December 2023

Abstract
Background
Laser powder bed fusion (L-PBF) additive manufacturing (AM) is used for building metallic parts layer-by-layer and often generates non-uniform thermal gradients between layers during fabrication, resulting in the development of residual stresses when parts are cooled down.

Objective
The impact of modulated laser used during the L-PBF process on residual stresses in Inconel 718 (IN718) material was investigated. The impact of build directions on residual stress is also determined.

Methods
The contour method is employed to measure the full-field residual stress component on the cross-section of samples. A complementary residual stress measurement method, incremental hole drilling, was employed for obtaining in-plane residual stress components.

Results
The results show that the residual stress distribution is sensitive to the build direction, with a higher magnitude of residual stress in the direction of build than that in the transverse direction. Multiple measurements with the same manufacturing parameters show good repeatability.

Conclusion
Residual stresses in the as-built parts are significant and hence a further consideration regarding relieving residual stresses is required when post-thermal treatments are developed.
Spontaneous Comparison of Nanotechnology and Controversial Objects among Laypersons, Scientists and Environmentalists
Authors: Brunel Maïté , Launay Céline , Henry Maryelle , Cascino Nadine , Py Jacques , Le Floch Valérie 
Published: December 2023

AbstractNanotechnologies are a controversial topic, as they seem promising but also cause concern. Previous research has highlighted the potential link between nanotechnologies and other hazardous technologies. The aim of this research was to analyse the discourse on this topic by three groups of participants: laypersons, scientists and environmentalists. Thirty-four people (13 laypersons, ten scientists and eleven environmentalists) were interviewed using a semi-structured interview. Lexical and thematic analyses showed that scientists engage in explanatory discourse and perceive fewer risks than laypersons and environmentalists. The latter two groups describe applications and list the main actors in the development of nanotechnologies. Environmentalists are significantly more likely to make spontaneous associations with other technologies, such as electromagnetic waves, and perceive more risks than the other two groups. Contrary to our expectations, laypersons make fewer associations with biotechnologies than experts or environmentalists. The results are discussed in terms of the interest of a qualitative approach to uncovering new objects spontaneously associated with nanotechnologies, as well as in terms of a risk governance framework.
On the uniqueness of a meromorphic function and its higher difference operator under the purview of two shared sets
Authors: Mallick Sanjay , Basak Pratap 
Published: December 2023

AbstractIn the paper, we investigate the uniqueness problem of a meromorphic function and its difference operator to the most general setting via two shared set problems and thus improve a recent result of Chen–Chen (Bull Malays Math Sci Soc 35(3): 765-774, 2012) .
Repetitorium Sonographie der Nieren Teil 1: technische Grundlagen und korrekte Durchführung der Untersuchung
Authors: Tsarov Dimitar , Furrer Marc A. 
Published: December 2023

ZusammenfassungDie transabdominale Sonographie ist schon lange ein integraler Bestandteil der alltäglichen urologischen Praxis und spielt bei der Erstbeurteilung des Urogenitaltrakts (in der Regel klassische Grauwertsonographie, B‑Modus), im Rahmen der Nachsorge sowie bei komplexen Fragestellungen wie der Abgrenzung malignomsuspekter Nierenraumforderungen mittels kontrastmittelverstärkten Ultraschalls (CEUS) eine wichtige Rolle. Sie stellt ein kosteneffizientes, nichtinvasives und ubiquitär verfügbares Diagnoseverfahren dar, welches aufgrund der fehlenden Strahlenbelastung auch bei speziellen Patientengruppen wie Kindern und Schwangeren bedenkenlos angewendet werden kann. Die Nierensonographie geniesst einen hohen Stellenwert, da die Niere von ihrer Lage her optimal zugänglich ist, gut dargestellt werden kann und Nierenpathologien oft durch anschauliche Organalterationen gekennzeichnet sind, die sonographisch pathognomonisch abgebildet werden können.Allerdings ist die Diagnostik untersucherabhängig und die Interpretation daher für Drittpersonen nicht immer trivial. Trotz ihrer unbestrittenen Untersucherabhängigkeit bleibt die Nierensonographie eine wertvolle Untersuchung, die auch in der Notfallsituation rasch eine Orientierung über mögliche renale Pathologien verschafft (z. B. Beurteilung einer Nierenstauung bei Flankenkoliken und Verdacht auf Urosepsis oder als E‑FAST [„extended focused assessment with sonography in trauma“] als bettseitiges Ultraschallprotokoll zum Nachweis von freier Flüssigkeit als Indiz für ein Urinom oder Hämatom beim Nierentraumapatienten). Die konventionelle Sonographie ist essenziell für die Indikationsstellung von weiteren diagnostischen und therapeutischen Massnahmen. Dank der technischen Entwicklung mit der im Laufe der Zeit deutlich verbesserten Bildwiedergabe, der Herstellung von kompakten portablen Geräten, die problemlos im ambulanten Setting bei z. B. institutionalisierten Patienten eingesetzt werden können, und der flachen Lernkurve werden für diese Untersuchungsmodalität auch zukünftig weite Perspektiven in Aussicht gestellt.Diese Übersichtsarbeit soll als praxisorientiertes Repetitorium der Nierensonographie mit Fokus auf technische Grundlagen und korrekte Durchführung der Untersuchung dienen. Es wird auf die Entwicklung dieser Untersuchungstechnik sowie die technischen Details gezielt eingegangen.
A vertically translating collection system to facilitate roll-to-roll centrifugal spinning of highly aligned polyacrylonitrile nanofibers
Authors: Ippolito Jason , Beachley Vince 
Published: December 2023

AbstractCentrifugal spinning is a fiber spinning method capable of producing fibers in the nanoscale diameter range from a multitude of polymers, including polyacrylonitrile (PAN). With a traditional centrifugal spinner, fiber can be rapidly spun and collected on static collection posts. However, the use of posts inevitably forms a dense fiber “ring” that is incompatible with roll-to-roll manufacturing processes. In this work, factors that influence throughput and scalability of highly aligned centrifugally spun PAN fibers are explored. A custom centrifugal setup is used to vertically translate collected fibers during the spinning process to distribute them over a large surface area. In addition, factors that affect PAN fiber diameter during the spinning process are investigated, including spinneret to collector distance, rotational speed, and humidity. Resulting data demonstrates that these factors can be independently optimized to reliably produce quality PAN fiber in the nanoscale diameter range. Furthermore, the fiber mass collection rate can be increased without affecting sample quality when the vertical translation speed is increased. This work demonstrates the potential scalability of centrifugal spinning to quickly produce large amounts of highly aligned nanofiber in a cheap, efficient, and reliable manner, and also lends the ability to be collected in a roll-to-roll fashion.
Solidarity with Chrystul Kizer: On Disparate Failures of Knowledge-Attribution and Survivors of Sexual Violence
Authors: Spencer Ayanna De'Vante 
Published: December 2023

AbstractI write in solidarity with Chrystul Kizer, a criminalized Black teen survivor of sexual violence in Wisconsin, to detail how her ongoing legal fight occurs in a tilted sociopolitical and epistemological landscape with weighted opponents. I offer a theory of disparate failures of knowledge-attribution for survivors of sexual violence, a structural epistemological problem that I call constructed pragmatic encroachment (CPE). CPE explains that pragmatic encroachment is a nonneutral knowledge-attribution problem whereby attributors are empowered to affirm or deny a subject's knowledge-claim based on the subject's constructed practical stakes. Constructed practical stakes here refers to the potential costs/consequences of acting on knowledge of some p for some subject, “S,” constructed by their practical environment. Examining CPE in Kizer's self-defense case, I highlight why real-world pragmatic encroachment is exceptionally alarming for survivors of sexual violence, especially criminalized survivors. The epistemological problem is not merely whether people in powerful positions are frequently fallible, but the convergence of sociopolitical and epistemic power to deny what survivors know about our own experiences of violence, and power to punish survivors for acting on what we know.
DIVERGENT MODELS WITH THE FAILURE OF THE CONTINUUM HYPOTHESIS
Authors: TRANG NAM 
Published: December 2023

Abstract
We construct divergent models of

$\mathsf {AD}^+$

along with the failure of the Continuum Hypothesis (

$\mathsf {CH}$

) under various assumptions. Divergent models of

$\mathsf {AD}^+$

play an important role in descriptive inner model theory; all known analyses of HOD in

$\mathsf {AD}^+$

models (without extra iterability assumptions) are carried out in the region below the existence of divergent models of

$\mathsf {AD}^+$

. Our results are the first step toward resolving various open questions concerning the length of definable prewellorderings of the reals and principles implying

$\neg \mathsf {CH}$

, like

$\mathsf {MM}$

, that divergent models shed light on, see Question 5.1.
Phylogenetic position of the Neotropical Family Zonocotylidae (Paramphistomoidea) using partial 28S rDNA sequences
Authors: Montes M.M. , Arrascaeta F.K. , Barneche J.A. , Balcazar D. , Reig Cardarella G.F. , Martorelli S.R. 
Published: December 2023

Abstract
Six families belonging to the Paramphistomoidea superfamily have been reported in South America, with only Zonocotylidae and Balanorchiidae being endemic. The Zonocotylidae was initially classified as Aspidogastrea and then as a paramphistomoid. This family comprises a single genus, Zononocotyle, with two species. It is primarily characterized by having an attachment organ with transverse ridges and a single testis. The placement of Zonocotylidae within Paramphistomoidea is controversial, as some researchers speculate that this genus is the most primitive member of the superfamily, while others consider it an aberrant form. The main objectives of our study were to provide the first sequences of Zonocotylidae and elucidate its phylogenetic position. We amplified the 28S gene from two parasites from Cyphocharax sp. from Punta Lara, Buenos Aires. Newly generated sequences were used to infer the phylogenetic relationships with other Paramphistomoidea species using a Bayesian approach. Zonocotylidae were clustered with Dadayiinae and Kalitrematinae (Cladorchiidae) species found in freshwater fishes from South America. Genetic analyses revealed that they formed a well-supported clade with cladorchiids in freshwater hosts from South America. However, the occurrence of genera of Cladorchiidae in North America, Middle America, Asia, and Australia suggested its polyphyletic nature and may indicate the need for the erection of new families. Other Paramphistomoidea families may also require further revision. The addition of new sequences to phylogenetic analyses along with a comprehensive and more detailed description of the genera will help resolve the relationships within this group.
Models of vision need some action
Authors: Rothkopf Constantin , Bremmer Frank , Fiehler Katja , Dobs Katharina , Triesch Jochen 
Published: December 2023

Abstract
Bowers et al. focus their criticisms on research that compares behavioral and brain data from the ventral stream with a class of deep neural networks for object recognition. While they are right to identify issues with current benchmarking research programs, they overlook a much more fundamental limitation of this literature: Disregarding the importance of action and interaction for perception.
Deathbed experiences and meaning-making: Perspectives of family caregivers of patients who received cancer palliative care
Authors: Teo Irene , Paramasivam Keerthana , Chee Wai Yee , Ng Carolyn , Neo Patricia Soek Hui , Lee Geok Ling 
Published: December 2023

AbstractObjectivesThe deathbed symbolizes a time when the patient is dangerously ill and where death is imminent. The memories of family caregivers during this time can potentially shape their meaning-making of the patient’s death and bereavement adjustment. We aimed to understand the experiences of family caregivers at the deathbed of patients receiving palliative care. We also examined caregiver’s meaning-making that occurred after the patient’s death.MethodsIn this retrospective qualitative study, family caregivers of cancer patients who received palliative care in Singapore were recruited through purposive sampling. In-person, semi-structured interviews were individually conducted with study participants to understand their experiences from a caregiver’s perspective before and after the death of the patient. Thematic content analysis method was conducted.ResultsA total of 25 bereaved family caregivers were interviewed, with spouses, adult children, and others comprising one-third each of the sample. Six themes emerged from caregivers’ recollected experiences around the patient deathbed: Lasting image of the patient, A time of intense emotions, Healthcare providers prepare caregivers, A time for saying goodbye, Rituals provide comfort, and Impact on family ties. Four themes emerged surrounding post-loss meaning-making: An end to the pain and suffering, “Have I done enough?,” Significance in the timing of events, and Gaining strength and personal growth.Significance of resultsThe deathbed is a salient time for family caregivers as they prepare for patient’s death. There are opportunities to provide support to the family based on the study findings.