bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of Dynamic Force Coefficients for an Additively Manufactured Hermetic Squeeze Film Bearing Support Damper Utilizing a Pass-Through Channel
Authors: Ertas Bugra , Gary Keith , Adcock Tom 
Published: October 2023

Abstract
The following paper presents breakthrough experimental results for a new hermetic squeeze film damper (HSFD) concept that is integrally designed within an externally pressurized tilting-pad radial gas bearing support. The flexibly damped gas bearing module was designed for a 7.2″ (183 mm) diameter shaft and fabricated using direct metal laser melting (DMLM); also known as additive manufacturing. The bearing and HSFD were sized based on ongoing studies for oil-free supercritical carbon dioxide (sCO2) power turbines in the 8.5 MW–10 MW power range. The development of the new damper concept was motivated by past dynamic testing on HSFD, which generated frequency-dependent stiffness and damping force coefficients. In efforts to eliminate the frequency dependency, a new HSFD architecture was conceived that adds accumulator volumes and a pass-through channel to previously conceived HSFD flow network designs. The other motivation for the work is the need to develop a cost-effective and reliable oil-free bearing technology that is scalable to large power turbomachinery applications. There were several objectives for the following work. The first objective was to successfully design and fabricate a single piece bearing-damper using additive manufacturing, while dimensionally controlling critical design features. The paper discusses the manufacturing steps and shows cut-ups that reveal adequate clearance control capability with internal damper clearances. The second objective was to perform experimental testing with the new HSFD design in efforts to extract stiffness and damping coefficients for excitation frequencies within 20–160 Hz and peak vibration amplitudes between 0.25 mils (6.35 microns) to 1 mil (25.4 microns). The test results for a single HSFD bearing module indicated that the design modifications to the HSFD architecture were successful in eliminating nearly all the frequency dependencies for the stiffness force coefficient. The dynamic tests yielded a stiffness coefficient that varied between 112 klb/in. (19.6 MN/m) and 96 klb/in. (16.8 MN/m). The damping force coefficient however, exhibited relatively more variation with frequency with values residing between 175 lb-s/in. (31 kN-s/m) to 214 lb-s/in. (37 kN-s/m). Finally, the paper advances a three-dimensional fluid-structure interaction (FSI) model using transient finite element analysis (FEA) coupled to a computational fluid dynamics (CFD) model. The FSI analysis performed between 20 Hz and 80 Hz was used to predict the stiffness and damping of the HSFD using a quarter-section model of the damper. The FSI analysis was able to support test results by showing only a 6–7.4% change in the magnitude of force coefficients. Stiffness predictions agree reasonably well with experiments whereas damping is underpredicted.
Six Weeks of Unilateral Flywheel Hip-Extension and Leg-Curl Training Improves Flywheel Eccentric Peak Power but Does Not Enhance Hamstring Isokinetic or Isometric Strength
Authors: de Keijzer Kevin L. , McErlain-Naylor Stuart A. , Beato Marco 
Published: October 2023

Purpose: This preregistered trial investigated how 6 weeks of unilateral flywheel leg-curl and hip-extension training impact isokinetic, isometric, and flywheel strength and power outcomes. Methods: The study involved 11 male university athletes (age 22 [2] y; body mass 77.2 [11.3] kg; height 1.74 [0.09] m) with one leg randomly allocated to flywheel training and one leg to control. Unilateral eccentric and isometric knee-flexion torque and flywheel unilateral leg-curl and hip-extension peak power were tested. Training intensity and volume (3–4 sets of 6 + 2 repetitions) were progressively increased. Results: The intervention enhanced hip-extension concentric (P < .01, d = 1.76, large) and eccentric (P < .01, d = 1.33, large) peak power more than the control (significant interaction effect). Similarly, eccentric (P = .023, d = 1.05, moderate) peak power was enhanced for the leg curl. No statistically significant differences between conditions were found for isokinetic eccentric (P = .086, d = 0.77, moderate) and isometric (P = .431, d = 0.36, small) knee-flexor strength or leg-curl concentric peak power (P = .339, d = 0.52, small). Statistical parametric mapping analysis of torque–angle curves also revealed no significant (P > .05) time–limb interaction effect at any joint angle. Conclusion: Unilateral flywheel hamstring training improved knee-flexor eccentric peak power during unilateral flywheel exercise but not flywheel concentric, isokinetic eccentric, or isometric (long-lever) knee-flexor strength.
Studying on failure compensation in low-energy region of superconducting cavity in CAFe2
Authors: Jia Yongzhi , Chen Xiaolong , Li JiaoSai , Sun Kunxiang , Wang Zhijun , Qi Xin , He Yuan 
Published: October 2023

The high availability of Accelerator-Driven Sub-critical system (ADS) facilities poses a major challenge for the accelerators, which sets stringent requirements on the beam trip rate. However, beam trips caused by component failures in the low-energy region of the superconducting (SC) radio-frequency (RF) cavity are always a bottleneck for the long-term stable operation of high-power beams. In this paper, we present a compensation method. This method can be used to compensate for cavity faults that occur at low-energy ([Formula: see text][Formula: see text]MeV). The compensation is achieved by rematching the beam with nearby components and compensating for energy using all cavities. The new Epeak and RF phases of the remaining components are calculated in the simulation environment using a multi-objective genetic algorithm. The compensation scheme is then tested on the super-heavy element research accelerator II (CAFe2). The experimental results show that the scheme can compensate for the energy, maintaining the same level as the normal operation status, while keeping the transmission efficiency [Formula: see text]. The entire compensation process takes only 36[Formula: see text]s. This is the first compensation experiment in the low-energy region, and it demonstrates the feasibility of long-term stable operation.
First-order linear Marcus SPDEs
Authors: Hartmann Lena-Susanne , Pavlyukevich Ilya 
Published: October 2023

In this paper, we solve a Lévy driven linear stochastic first-order partial differential equation (transport equation) understood in the canonical (Marcus) form. The solution can be obtained with the help of the method of stochastic characteristics. It has the same form as a solution of a deterministic PDE or a solution of a stochastic PDE driven by a Brownian motion studied by Kunita [First order stochastic partial differential equations, in Stochastic Analysis. Proc. Taniguchi Int. Symp. Stochastic Analysis, Katata and Kyoto, 1982, North-Holland Mathematical Library, Vol. 32, ed. K. Itô (North-Holland Publishing Company, 1984), pp. 249–269; Stochastic Flows and Stochastic Differential Equations, Vol. 24 (Cambridge University Press, 1997)].
Territorial Dynamics Supported by a Collaborative Network of Innovation Labs: Toward an Approach to Establish a Portfolio of Indicators to Monitor and Assess their Territorial Impact
Authors: Pruvot Fanny , Dupont Laurent , Morel Laure 
Published: October 2023

The multiplication of apparently similar Innovation Labs throughout the local territories raises questions about their role and their positioning. Innovation Labs are generally supplied by local resources. This substantial growth could facilitate the connection of various regions within a territory, thereby creating new areas for experimentation. The public authorities need these labs to bring added value to their territory. This study shows that a network of Innovation Labs could be a strategic means to support territorial dynamics at a local scale. The literature does not provide concrete tools, resources, and methods to evaluate the territorial impacts of Innovation Labs. Furthermore, no literature review regarding the networking of Innovation Labs in a territory has yet been conducted. This paper begins to fill this gap and shows that the linking of innovation labs can support territorial dynamics. Through a review of the literature, research trends pertaining to territorial dynamics and innovation laboratories were identified. The contribution of this paper is the proposal of an approach to design a system of indicators to analyze a network of ILs adapted to a local territory as well as a portfolio of indicators. These results will allow us to follow the evolution of these labs, their interactions and their impacts on a local territory.
The Effect of Sustainable Applications of Chitin and Chitosan to Remove Dyed Pollutants Using Adsorption: A Review
Authors: Moradi O. , Hosseinian Naeini A. , Kalaee M. R. , Mirkhan S. M. R. 
Published: October 2023

Sustainable wastewater treatment methods are very important and necessary because they help to protect the environment and the health of humans, animals and other living organisms. With the increase in industries and population, toxic dyes produced in various industries have created a serious issue for public health and the main concern of environmental protection. This method affects the quality of purified water and causes various diseases, and as a result, it ends in death. Water purification is very important and plays an important role in the environment. Pollutant removal has different methods that include physicochemical and biological treatment. Each of these methods shows different pollutant removal capabilities that are studied here, depending on the experimental limitations. Among the different methods of wastewater treatment, the methods that have a high cost are not used today, and the results have shown that researchers consider more in the fields that have a low cost of material and testing. Surface adsorption is considered the most efficient method due to its high removal efficiency, easy operation, cost-effectiveness and recyclability of adsorbents. In this paper, the sustainable applications of wastewater treatment for the removal of colored pollutants have been investigated. Here, chitin and chitosan are more commonly used nowadays due to the naturalness of the polymer material, and it is not toxic and has many uses in various fields that can be used by adsorption. In this context, this work aims to provide a comprehensive summary of the adsorption of dyes from wastewater by nano-biopolymers, especially chitin and chitosan, as adsorbents. First, a summary of biopolymers, the properties of chitin and chitosan and synthesis techniques are presented. After the classification of dyes, the techniques for removing them from the wastewater are described. In addition, the adsorption process and isotherms used for adsorption are described with different models. Among various adsorbents, such as carbon materials, metals/metal oxides and zeolites, nano-biopolymers, especially chitin and chitosan, are the most promising ones for environmental sustainability. The results show that the use of biocompatible biopolymers to remove dye pollutants in different dyeing and textile industries plays an important role in determining the sustainable methods of wastewater treatment and can reduce the environmental effects of industries. Surface adsorption can be compatible with the environment and remove various colored pollutants well so that we have clean and pollution-free water and can use water.
Genetic data to describe the hybrid zone between Bufo bufo (Linnaeus, 1758) and Bufo verrucosissimus (Pallas, 1814) in northeastern Türkiye
Authors: Dursun Cantekin , Sánchez-Montes Gregorio , Özdemir Nurhayat , Gül Serkan , Martínez-Solano Iñigo 
Published: October 2023

Abstract
Hybrid zones are geographic areas where individuals from distinct taxa meet, mate, and hybridize. These zones may have complex histories, but many of them originated relatively recently, during climatic oscillations in the Quaternary, following range shifts of formerly isolated, well-differentiated lineages. The Bufo bufo species group comprises four species distributed over the Western Palearctic. Whereas the contact zone between Bufo bufo and B. spinosus in western Europe has been well characterized, little is known about other species contacts. Here we focused on the contact between B. verrucosissimus and B. bufo in northeastern Türkiye, using mtDNA and microsatellite markers to describe genetic structure and patterns of admixture in the hybrid zone based on Bayesian clustering and cline analyses. Both species meet in a narrow contact zone at Rize province, with restricted introgression suggesting barriers to hybridization consistent with species status. Spatial population genetic analyses of microsatellite data pinpoint a possible enclave population of B. bufo at the Borçka district in Artvin province, isolated within the B. verrucosissimus range. The centers of the microsatellite and mtDNA-based clines are slightly displaced, with B. verrucosissimus mtDNA introgressing about 33 km W of the nuclear contact. Hybrid zone dynamics seem to be associated with range shifts mediated by Pleistocene glacial cycles and/or sex-biased dispersal.
Insights Into Metformin XR Pharmacotherapy Knowledge Among Community Pharmacists: A Cross-Sectional Study
Authors: Jairoun Ammar Abdulrahman , Al-Hemyari Sabaa Saleh , Shahwan Moyad , Hassan Nageeb , Zyoud Sa’ed H , Jaber Ammar Ali Saleh , Al-Qirim Tariq 
Published: October 2023

Background: There is a little knowledge on the extent to which healthcare providers understand and accept the professional recommendations and appropriate dosing strategy regarding metformin XR. Objectives: To evaluate UAE community pharmacists’ knowledge, attitude, and practices (KAP) concerning metformin XR. Methods: This is a cross-sectional research study conducted amongst licensed community pharmacists. The survey took place via a questionnaire and physical interviews were held. The survey used in this study included questions on demographics and questions on the participants’ attitudes, knowledge and practices concerning metformin XR. The factors influencing KAP regarding metformin XR were examined via simple logistic regression analysis. Results: Threehundred fifty-three (n = 353) participants were recruited in the study. Independent pharmacies constituted 57.5% of this study sample and 42.5% were chain pharmacies. The average knowledge score about metformin XR tablets was 42.5% with a confidence interval (CI) of 95% [37.3%, 47.4]. Better knowledge scores on metformin XR tablets was observed in respondents aged ⩾40 years (OR 2.97, 95% CI 1.63-5.4), having greater than 10 years in terms of experience (OR 2.28; 95% CI 1.25-4.16) and pharmacist graduated from Regional or international universities (OR 2.08; 95% CI 1.34-3.24). About 78% (n = 275) of the participants believed that metformin XR tablets have better efficacy and 63.2% (n = 233) indicated that metformin IR was associated with greater adverse effects. Conclusion: This study demonstrated a distinct gap in knowledge, attitude and practice pertaining to metformin XR among community pharmacists in the UAE. The community pharmacists need to enhance their practice by receiving accurate and reliable data to support their decision-making on the prescribing of metformin XR. The implementation of novel guidelines and evidence dissemination strategies may help bridge this gap.
Quercetin supplementation attenuates airway hyperreactivity and restores airway relaxation in rat pups exposed to hyperoxia
Authors: Kryeziu Islam , Reçica Shkëlzen , Thaçi Qëndrim , Kurshumliu Fisnik , Hadzi-Petrushev Nikola , Basholli-Salihu Mimoza , Mladenov Mitko , Sopi Ramadan B 
Published: October 2023

Hyperoxia exposure of immature lungs contributes to lung injury and airway hyperreactivity. Up to now, treatments of airway hyperreactivity induced by hyperoxia exposure have been ineffective. The aim of this study was to investigate the effects of quercetin on hyperoxia-induced airway hyperreactivity, impaired relaxation, and lung inflammation. Newborn rats were exposed to hyperoxia (FiO2 > 95%) or ambient air (AA) for seven days. Subgroups were injected with quercetin (10 mg·kg−1·day−1). After exposures, tracheal cylinders were prepared for in vitro wire myography. Contraction to methacholine was measured in the presence or absence of organ bath quercetin and/or Nω-nitro-L-arginine methyl ester (L-NAME). Relaxation responses were evoked in preconstricted tissues using electrical field stimulation (EFS). Lung tumor necrosis factor-alpha (TNF-α) and interleukin-1β (IL-1β) levels were measured by enzyme-linked immunosorbent assay (ELISA). A P < 0.05 was considered statistically significant. Contractile responses of tracheal smooth muscle (TSM) of hyperoxic animals were significantly increased compared with AA animals ( P < 0.001). Treatment with quercetin significantly reduced contraction in hyperoxic groups compared with hyperoxic control ( P < 0.01), but did not have any effect in AA groups. In hyperoxic animals, relaxation of TSM was significantly reduced compared with AA animals ( P < 0.001), while supplementation of quercetin restored the lost relaxation in hyperoxic groups. Incubation of preparations in L-NAME significantly reduced the quercetin effects on both contraction and relaxation ( P < 0.01). Treatment of hyperoxic animals with quercetin significantly decreased the expression of TNF-α and IL-1β compared with hyperoxic controls ( P < 0.001 and P < 0.01, respectively). The findings of this study demonstrate the protective effect of quercetin on airway hyperreactivity and suggest that quercetin might serve as a novel therapy to prevent and treat neonatal hyperoxia-induced airway hyperreactivity and inflammation.
Development of a Novel Rat Knee Osteoarthritis Model Induced by Medial Meniscus Extrusion
Authors: Fukui Daisuke , Nishiyama Daisuke , Yamanaka Manabu , Tamai Hidenobu , Nishio Naoko , Kawakami Mamoru , Yamada Hiroshi 
Published: October 2023

Objective The medial meniscus extrusion (MME) is associated with increased stress on the knee joint, which leads to cartilage degeneration. To evaluate the etiology of knee osteoarthritis, it is extremely important to create animal models of the disease that more closely resemble actual clinical conditions in terms of symptomatology, molecular biology, and histology. This study aimed to create a clinically relevant model of MME in rats. Design Behavioral, molecular biological, and histological changes in the newly developed rat MME model were compared with those in sham and medial meniscus transection and medial collateral ligament transection (MMT) models to examine the characteristics of this model. Results In the MME rat model, behavioral evaluation shows abnormalities in gait compared with the other 2 groups, and molecular biological evaluation of the infrapatellar synovia of rats shows that gene expression of inflammatory cytokines, matrix-degrading enzymes, and pain-related nerve growth factor was increased compared with the sham group. Furthermore, histological evaluation reveals that cartilage degeneration was the most severe in the MME group. Conclusions The newly developed MME model reproduced the characteristic pathology of MME in clinical practice, such as severe pain, inflammation, and rapid progression of osteoarthritis. The MME model, which might more closely mimic human knee osteoarthritis (OA), could be a useful model for elucidating the pathophysiology and considering therapeutic management for knee OA.
Self-sacrificial leadership, thriving at work, workplace well-being, and work–family conflict during the COVID-19 crisis: The moderating role of self-leadership
Authors: Huang Danyu , Zhou Hao 
Published: October 2023

The COVID-19 crisis has created instability in nurses’ workplace well-being (WWB) and work–family relationships. Exploring effective leadership tailored to the needs in a special context is significant to address these issues. Therefore, we examined how the interaction of self-sacrificial leadership (SSL) and self-leadership (SL)—explaining in the integration of conservation of resources and self-determination theories—related to thriving at work (TAW), WWB, and work–family conflict (WFC). A multi-wave questionnaire was distributed to 405 nurses working at a large hospital in China. The results indicate that (1) SSL brought more WWB and less WFC, (2) TAW mediated the correlations between them, and (3) SL stimulated more TAW than did SSL and weakened the influence of SSL on TAW. Alongside improving the understanding of the role of SSL and SL during the COVID-19 pandemic, we facilitate management interventions to practitioners. JEL CLASSIFICATION: L200
Intravenous thrombolysis with tenecteplase versus alteplase combined with endovascular treatment of anterior circulation tandem occlusions: A pooled analysis of ETIS and TETRIS
Authors: Marnat Gaultier , Lapergue Bertrand , Gory Benjamin , Kyheng Maeva , Labreuche Julien , Turc Guillaume , Olindo Stephanze , Sibon Igor , Caroff Jildaz , Smadja Didier , Chausson Nicolas , Clarençon Frederic , Seners Pierre , Bourcier Romain , Pop Raoul , Olivot Jean-Marc , Mazighi Mikael , Moulin Solène , Janot Kevin , Cognard Christophe , Alamowitch Sonia , Gerschenfeld Gaspard 
Published: October 2023

Background: Tandem occlusions are a singular large vessel occlusion entity involving specific endovascular and perioperative antithrombotic management. In this context, data on safety and efficacy of prior intravenous thrombolysis (IVT) with tenecteplase is scarce. We aimed to compare IVT with tenecteplase or alteplase in patients with acute tandem occlusions intended for endovascular treatment. Patients and methods: A retrospective pooled analysis of two large observational registries (ETIS (Endovascular Treatment of Ischemic Stroke) and TETRIS (Tenecteplase Treatment in Ischemic Stroke)) was performed on consecutive patients presenting with anterior circulation tandem occlusion treated with IVT using either alteplase (ETIS) or tenecteplase (TETRIS) followed by endovascular treatment between January 2015 and June 2022. Sensitivity analyses on atherosclerosis related tandem occlusions and on patient treated with emergent carotid stenting were conducted. Propensity score overlap weighting analyses were performed. Results: We analyzed 753 patients: 124 in the tenecteplase and 629 in the alteplase group. The overall odds of favorable outcome (3-month modified Rankin score 0–2) were comparable between both groups (49.4% vs 47.1%; OR = 1.10, 95%CI 0.85–1.41). Early recanalization, final successful recanalization and mortality favored the use of tenecteplase. The occurrence of any intracranial hemorrhage (ICH) was more frequent after tenecteplase use (OR = 2.24; 95%CI 1.75–2.86). However, risks of symptomatic ICH and parenchymal hematoma remained similar. In atherosclerotic tandems, favorable outcome, mortality, parenchymal hematoma, early recanalization, and final successful recanalization favored the tenecteplase group. In the carotid stenting subgroup, PH were less frequent in the tenecteplase group (OR = 0.18; 95%CI 0.05–0.69). Conclusion: In patients with tandem occlusions, IVT with tenecteplase seemed reasonably safe in particular with increased early recanalization rates. These findings remain preliminary and should be further confirmed in randomized trials.