bluuebunny/crossref_metadata_2025_split huggingface dataset:
Al-Tajârib wa al-Taḥadiyyât ‘inda Muta’allimi al-Lughah al-‘Arabiyyah fî âdâi Ikhtibar al-Lughah al-Mi’yârîy (TOAFL)
Authors: Rahman Aulia , Supriani Ria Rafita 
Published: February 2024

Purpose- This study aims to describe the experience of STAIN Mandailing Natal Arabic students in taking the TOAFL test, both when taking the TOAFL exam and when doing TOAFL questions. This study also describes the challenges faced by students in taking the TOAFL test.
Design/Methodology/Approach- The study used a qualitative approach based on analytical descriptive methods and used two data collection methods, namely questionnaires and interviews.
Findings- In this study, it can be seen that (1) the average Arabic student is very happy when taking the toafl exam because it can measure their Arabic language skills and not all students are selected in participating in the activity, (2) in doing toafl questions there are difficulties, namely the audio istima is very fast so they cannot hear well and long qiraah questions make students become bored and panic. (3) The challenges faced by students are regarding timing, lack of practice, inadequate facilities and infrastructure and the atmosphere of the exam.
Research Limitation/Implications- With the research, it is expected that all TOAFL organizers will see and pay attention to the factors that are difficulties and challenges in the TOAFL test, especially non-linear factors so that the implementation of the exam can be maximized
Cytokine profile in patients with vibration disease, aggravated by hypertension and obesity
Authors: Chistova N. P. , Bodienkova G. M. 
Published: February 2024

Comorbid diseases which include arterial hypertension (AH) accompanied by overweight, and vibration disease (VD) are known to contribute to the mutual aggravation of occupational and cardiovascular pathology. Despite numerous studies indicating that some changes of immune system are observed when exposed to vibration, the contribution of cytokines to the comorbid course of vibration disease has not been sufficiently studied. The aim of the work is to evaluate the role of inflammatory mediators in development of hypertension and obesity in vibration disease.The cytokine profile parameters were determined by ELISA immunoassay using “Vector-Best” test systems. Some unidirectional changes in serum cytokine concentrations were found in patients with VD complicatedby AH, and those with VD without AH, being characterized by increase in pro-inflammatory IL-1β, TNFα, IL-17, anti-inflammatory IL-4 and IFNγ, and a decrease in multifunctional IL-2 cytokinem, relative to the comparison group. The groups with versus without AH differed in compensatory increase of anti-inflammatory IL-10 in the latter group. At the same time, all patients with combined VD and AH had excessive body weight, with grade 1 obesity in half of the cases, thus being significantly different from those with VD without AH. It is shown that IL-1β, IL-2, IL-4, IL-8, TNFα play an apparent role in the development of obesity. The greatest contribution is observed for IL-1β, as evidenced by the quantitative relationship of body mass index with its concentrations as assessed by logistic regression analysis. The limitation of this study may be a small sample size.It was found that the unidirectional changes in cytokines when compared to the comparison group were revealed in patients with VD complicated by AH, and in patients with VD without AH. In the subjects with VD and AH, these changes were more pronounced, which may suggest the hypertension is an aggravating factor. The established relationship between individual cytokines (IL-1β, IL-2, IL-4, IL-8, TNFα) and BMI indicates their participation in development of obesity. All these findings may provide a basis for development of preventive and therapeutic measures that reduce the risk of hypertension and obesity in the people working under permanent exposure of vibration.
Features of innate immunity in children with hypertrophy of the palatine tonsils
Authors: Grankovsky V. A. , Karpova E. P. , Gankovskaya L. V. , Avalyan Ya. S. , Merkusheva E. D. , Zinina E. V. 
Published: February 2024

Hypertrophy of pharyngeal lymphoid tissue is among the most common problems in pediatric otorhinolaryngology, in particular, hypertrophy of the palatine tonsils. This disorder is characterized by increased size of a single or both palatine tonsils combined with various clinical symptoms. The principles of treatment in children with this pathology remain debatable, since the long-term effects of bilateral tonsillotomy are still not fully understood. The aim of the study was to assess the expression levels of genes encoding the innate immunity molecules (TLR4, HBD1, HBD2, IL1β) in the mucous membranes of palatine tonsils in children with palatine tonsillitis before and after treatment.We conducted a study of 78 patients divided into three independent groups. The 1st group (comparison) included 20 somatically healthy children. The 2nd group included 28 children with grade 2 palatine tonsil hypertrophy who underwent local treatment. The 3rd group included 30 children with grade 3 hypertrophy of the palatine tonsils, who, by clinical indications, underwent bilateral tonsillotomy. Determination and evaluation of innate immunity indices was carried out both before starting the treatment, and one month later, using the real-time PCR method.In children with hypertrophy of palatine tonsils, the initial values of TLR4 gene expression and antimicrobial peptides differed from those of healthy children. A decreased expression of HBD1 and HBD2 genes, which provide immediate protection against pathogens, was revealed. The values of TLR4 gene expression differed in groups of children with varying degrees of palatine tonsillar hypertrophy. In patients with bilateral tonsillotomy, an increased expression of TLR4 gene and a decreased expression of antimicrobial peptide genes (HBD1, HBD2) were revealed, which may indicate a readiness for development of tonsillar inflammation in response to pathogens. One month after surgical treatment, the indices of innate immunity were comparable with those of healthy children thus confirming the validity of surgical treatment. In the 2nd group of patients, the TLR4 gene expression one month after conservative treatment remained reduced, the expression of β-defensin HBD1 gene increased and exceeded the indicators of the group of healthy children, the expression level of the IL-1β gene was reduced.The revealed imbalance between the TLR4, HBD1 and HBD2 expression levels confirms an important role of innate immunity mechanisms in pathogenesis of palatine tonsillitis. The assessment of innate immunity indices may be used as an additional criterion in administration of therapy for hypertrophy of palatine tonsils and evaluation of its efficiency.
Evaluating the Antifungal Activity of Nano-curcumin against Candida Species Isolated from Otomycosis Patients
Authors: Hossein Kashirifar , Keyvan Kiakojouri , Saeid Mahdavi Omran , Akbar Hoseinnejad , Jalal Jafarzadeh , Reza Aminian Ahmad , Mohammad Jahangiri , Soghra Bagheri , Mojtaba Taghizadeh Armaki 
Published: February 2024

Background & Objective: Candida species are one of the most common causes of otomycosis. Antifungal drugs commonly used in treatment often have a variety of side effects, including toxicity, cross-reactivity, and drug resistance. In recent years, along with the advances in nanotechnology and the motivation to find new antifungal drugs, there has been a growing interest in the use of nanoparticles such as nano-curcumin in the treatment of fungal infections. The aim of this study was to evaluate the antifungal sensitivity of nano-curcumin on Candida species isolated from otomycosis.
Materials & Methods: In this experimental study, 100 isolated Candida samples from patients with otomycosis were included. Synthesis of nano-curcumin using chitosan (CS) nanoparticles was performed by ionic gelation method. Antifungal susceptibility testing was performed using broth microdilution method according to CLSI-M27-S4 guidelines on all Candida isolates to miconazole, clotrimazole and nanocurcumin. Data were analyzed in SPSS 27 software with independent t-test and chi-squared tests.
Results: Curcumin nanoparticles showed antifungal activity against all Candida species. However, the mean MIC of miconazole and clotrimazole for different Candida species was significantly lower than curcumin nanoparticles, indicating the lower antifungal effect of nano-curcumin than these two antifungals. Also, the mean MIC of nano-curcumin was not significantly different among Candida species (P < 0.05), whereas it was significantly different for miconazole and clotrimazole (P < 0.05).
Conclusion: The results of the present study showed that nano-curcumin had a lower antifungal effect than miconazole and clotrimazole, but due to nano-curcumin's safety, it can be used as a potential antifungal drug for the treatment of otomycosis after further investigation.
Pengaruh Pelatihan Range of Motion (ROM) pada CareGiver terhadap Kemandirian Activity Of Daily Living Pasien Pasca Stroke
Authors: Akbar M Agung , Rustiati Nelly , Supangat Supangat , Sujati Ni Ketut 
Published: February 2024

Stroke menjadi penyakit yang paling sering menyebabkan ketergantungan dan penurunan kemampuan fungsional pada penderitanya. Salah satunya adalah ketidakmampuan perawatan diri akibat kelemahan pada ekstremitas dan penurunan fungsi mobilitas yang dapat menghambat pemenuhan aktivitas harian. Penelitian ini bertujuan untuk mengetahui pengaruh program pelatihan Range Of Motion (ROM) pada caregiver pasien stroke di rumah sebagai upaya peningkatan kemandirian pasien pasca stroke. Desain Penelitian menggunakan quasi eksperiment. Teknik sampling dengan metode purposive sampling dan dilanjutkan simple random sampling saat dibagi kedalam kelompok intervensi atau kontrol. Adapun besar sampel yaitu 112 orang, dengan distribusi 56 kelompok intervensi dengan metode pelatihan ROM pada caregiver dan 56 kelompok kontrol dengan metode ceramah. Instrumen Penelitian menggunakan Indeks Katz. Analisis data menggunakan wilcoxon dan manwhitney. Hasil uji menunjukkan perbedaan yang signifikan antara kelompok intervensi dan kontrol dalam hal kemandirian klien dalam melakukan ADL dan kemampuan caregiver dalam melatih dengan masing-masing pvalue 0,00. Penelitian ini menyarankan pentingnya caregiver dalam perawatan pasien stroke sangat diperlukan untuk meningkatkan kualitas hidup dan perawatan harian pasien stroke.
The Difference of Chest Pain in Adult and Elderly Patients with Acute Myocardial Infarction
Authors: Widaryati Widaryati , Pratama Rendy Arya , Enaryaka Enaryaka 
Published: February 2024

Chest pain in an acute attack of myocardial infarction cannot be underestimated because this pain will have a harmful impact on the patient. Pain is influenced by personality, life stress, social economic factor, cognitive, and psychology factor. There is no study comparing chest pain between adult and elderly patients with coronary artery disease. Thus, this study to compare chest pain in patients with acute myocardial infarction in adults and the elderly. This research is a quantitative analytic study with a documentation study. With the purposive sampling technique, the number of samples in this study was 68 respondents. The statistical analysis employed the Mann Withney test. Out of total participant ( n=68), 72,1 % were elderly, 60,3 % were male and 79,4 % were STEMI. The results were obtained from the pain scale in adults with a mean value of 54.11 and a mean value at the elderly age 26.90 with a value of p (0.000). There is a significant difference between myocardial infarction pain in adults and acute myocardial infarction pain in the elderly. Adult more high intensity of pain than elderly patients. This study recommended that health workers so provide serious treatment for chest pain patients in elderly althaought the pain is not serious.
Dampak Tuberkulosis Terhadap Kesejahteraan Remaja
Authors: Angelia Ninuk , Dewi Nur Setiawati , Agushybana Farid 
Published: February 2024

Pendahuluan : Remaja telah diketahui berada pada peningkatan risiko infeksi baru dan tingkat kegagalan pengobatan yang lebih tinggi. Selain dampak pengobatan yang buruk, rendahnya dukungan sosial, dan masalah kesehatan mental juga mendukung temuan tersebut.
Tujuan: Menggambarkan dampak pengobatan TBC terhadap kesejahteraan remaja.
Metode: Review ini menggunakan pendekatan scoping review. Sumber literatur di peroleh melalui pencarian dengan menggunakan database yang terdiri dari PUBMED, Google Scholar, Science Direct dan Proquest. Kata kunci yang digunakan“Adolescents” OR “Youth” AND “Tuberculosis” AND “Impact” OR “Effect” AND “Wellbeing” OR “Happiness” OR “Life Satisfaction” OR “Quality of Life”. Kriteria inklusi dalam pemilihan artikel yaitu 1) rentang publikasi artikel 10 tahun terakhir; 2) Bahasa inggris; 3) tema artikel terkait dengan dampak TBC terhadap kesejahteraan remaja, 4) tersedia full teks dan spesifik.
Hasil: Berdasarkan artikel yang didapatkan, peneliti mengklasifikasikan kesejahteraan dalam empat aspek yaitu aspek fisik, psikologis, sosial, dan ekonomi.
Kesimpulan: Pengobatan TBC berdampak pada seluruh aspek perkembangan remaja. Dibutuhkan pelayanan TBC yang ramah untuk remaja sehingga dapat mempertahankan kesejahteraan remaja selama menjalani pengobatan.
Relationship between Knowledge Level about Anemia, Parents' Income and Menstrual Pattern with Anemia Status in Young Girls at 7th-Grade Junior High School Students in Palangka Raya City
Authors: Theresia Nita , Putri Fina Ratih Wira 
Published: February 2024

Background: One of the most common problems in adolescents was iron anemia. In adolescents who experience anemia, it would had very significant effects such as reduced body fitness, decreased learned abilities, suboptimal height, decreased physical abilities and pale faces.
Objective: : To analyze the relationship between knowledge levelled, parental income and menstrual patterns with anemia status in young girls at 7th-grade junior high school in Palangka Raya city.
Method: The design of this studied was an analytical descriptive with a quantitative cross-sectional studied, a sample of 146 of 1409 population of 7th-grade students spread across 47 schools in the city of Palangka Raya. The instrument used a knowledge questionnaire and a digital hemometer. The analysis used in this studied was the spearman correlation test and multiple logistic regression.
Result: : There was a relationship between the leveled of knowledge of anemia and anemia status in young girls at 7th-grade junior high school in Palangka Raya city (p-value=0.0001;r=0.325). There was a relationship between parents' income and anemia status in young girls at 7th-grade junior high school in Palangka Raya city (p-value=0.0001;r=0.392). There was a relationship between menstrual patterns and anemia status in 7th-grade junior high school girls in Palangka Raya city (p-value=0.006;r=0.227). Parents' income factor was the factor that most influences the incidence of anemia in young women (exp. B=8.241).
Conclusion: Knowledge was a protective factor which means a protective action in the form of anemia prevention behaviour.
Keywords: Anemia Status, Anemia Knowledge; Menstrual Patterns; Parents Income
Hubungan Iklim Keselamatan dengan Kekerasan di Tempat Kerja pada Perawat di Rumah Sakit Pemerintah Provinsi Aceh
Authors: Habibi Habibi , Maliki Imam , Faidhil Faidhil 
Published: February 2024

This study aims to explore the relationship between overtime and workplace violence (WPV) against nurses in the Government Hospital of Aceh Province. The research method employed is quantitative with a cross-sectional design. Data were collected from RSUD Aceh during the period of May 31 to June 14, 2022. Out of 161 respondents, 127 nurses successfully participated, resulting in a response rate of 78.9%. Sampling was conducted using a total sampling technique, involving nurses working in the emergency room, pediatric ward, pediatric surgery ward, male internal medicine ward, and internal medicine ward at the Government Hospital of Aceh Province. Data analysis was performed using univariate and bivariate approaches. The study found a significant relationship between overtime and psychological violence against nurses in RSUD Aceh (p=0.000). However, no significant relationship was found between physical violence among nurses at RSUD Aceh (p=0.290). In conclusion, overtime work is associated with the occurrence of psychological/non-physical violence against nurses working in the Government Hospital of Aceh Province.

Keywords: WPV, Overtime, Nursing
Hubungan Pola Makan Dengan Kejadian Gastritis pada Remaja : Literature Review
Authors: Puspitasari Tety Retno , Dhaneswari Pradhani , Putra Yonathan Kristian Yuan 
Published: February 2024

Masa pubertas pada remaja adalah masa dimana seorang remaja sedang mencari identitas diri, Mempunyai keinginan untuk diterima oleh teman dan mulai tertarik pada lawan jenis. Kemudian hal ini dapat mempengaruhi pola makan remaja, termasuk dalam penentuan makanan dan frekuensi makan. Pada remaja seringkali melakukan diet yang tidak sehat, bahkan sampai pola makannya terganggu sehingga menyebabkan gastritis. Oleh karena itu, penelitian ini bertujuan untuk menganalisis dan mengeksplorasi hubungan pola makan dengan kejadian gastritis pada remaja. Penelitian ini menggunakan pendekatan sistematik literature review. Sampel dalam penelitian ini berjumlah 7 jurnal, 6 jurnal yang bersumber dari google scholar dan 1 jurnal bersumber dari PubMed.yang sesuai dengan kriteria inklusi dan eksklusi untuk dianalisis. Dapat disimpulkan bahwa terdapat hubungan pola makan dengan kejadian gastritis pada remaja. Kepada peneliti selanjutnya diharapkan untuk mengembangkan dan menganalisis penelitian tentang hubungan pola makan dengan kejadian gastritis, dengan menambahkan variabel lain atau mengubah dengan metode lain seperti penelitian primer dengan metode penelitian kualit
Performa Kambing Peranakan Etawah (PE) Jantan yang Memperoleh Suplementasi Urea Moringa Molasses Multinutrien Block (UMMMB) dalam Ransum
Authors: Nugroho Indra Adi , Rizqiana Sista , Syarifuddin Nursyam Andi 
Published: February 2024

Penelitian ini bertujuan untuk mengetahui perbedaan performa kambing PE Jantan yang diberikan pakan tambahan berupa pakan suplemen UMMB dengan UMMMB. Penelitian ini menggunakan 8 ekor kambing PE jantan, 4 ekor diberi suplemen UMMB sebagai kontrol dan 4 ekor diberi pakan suplemen UMMMB sebagai perlakuan. Setiap kambing percobaan diberi pakan dengan kadar TDN 61% dan PK 13%. Setiap kambing percobaan diberi pakan hijauan dan pakan suplemen UMMB dan UMMMB sebanyak 200 gram. Perlakuan penelitian ini adalah P0 (Kontrol dengan pemberian hijauan rawa ad libitum + UMMB sebanyak 200 gram) dan P1 (Perlakuan dengan pemberian hijauan rawa ad libitum + UMMMB sebanyak 200 gram). Data yang di peroleh dianalisis dengan menggunakan uji banding yaitu uji t (t-Test Independent Sample). Hasil penelitian menunjukkan bahwa pemberian pakan suplemen UMMB dan UMMMB tidak menunjukkan perbedaan yang nyata (P>0,05) terhadap rataan konsumsi ransum harian (kg), rataan konsumsi bahan kering (BK), rataan PBBH (kg/ekor), dan rataan efisiensi ransum (kg) pada ternak kambing. Kelompok perlakuan UMMMB (P1) memiliki rataan PBBH lebih baik sebesar (0,074kg/ekor) dibandingkan kelompok kontrol UMMB (P0) (0,066kg/ekor).
Penggunaan Limbah Roti Sebagai Sumber Energi dalam Ransum Terhadap Bobot Akhir, Persentase Karkas, Persentase Lemak Abdominal dan IOFC Itik Peking
Authors: Taufik Muhammad , Sulaiman Abrani , Habibah Habibah 
Published: February 2024

Penelitian ini bertujuan untuk mengetahui pengaruh pemberian limbah roti dalam ransum terhadap bobot akhir, persentase karkas, persentase lemak abdominal dan IOFC itik peking. Penelitian dilaksanakan di Laboratorium Kandang Unggas sebagai tempat percobaan dan di Laboratium Nutrisi dan Makanan Ternak Fakultas Pertanian ULM Banjarbaru sebagai tempat uji laboratorium sampel. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL), dengan 5 perlakuan dan 4 ulangan, dimana setiap ulangan terdiri dari 4 ekor itik peking sehingga jumlah DOD yang digunakan adalah 80 ekor. Sebagai perlakuan adalah limbah roti dalam bentuk tepung pada pakan itik peking sebagai sumber energi pengganti jagung kuning. Perlakuan penelitian meliputi :P0 (Tanpa limbah roti (kontrol), P1 (Penggunaan limbah roti 10 % dalam ransum), P2 (Penggunaan limbah roti 20 % dalam ransum), P3 (Penggunaan limbah roti 30 % dalam ransum), P4 (Penggunaan limbah roti 40 % dalam ransum). Hasil penelitian penambahan tepung limbah roti 40% meningkatkan pertambahan bobot akhir sebesar 1,482,50 g/ekor, meningkatkan persentase karkas sebesar 64,73 % dengan kandungan lemak abdominal 2,96 %. Penambahan tepung limbah roti 40% menghasilkan IOFC tertinggi sebesar Rp 14,787 dan mampu menurunkan harga ransum dari Rp 5,419/ kg menjadi Rp 3,717/kg.
STUDI KERUSAKAN EKOSISTEM TERUMBU KARANG DI KAWASAN WISATA BAHARI PULAU LIUKANG LOE KABUPATEN BULUKUMBA PROVINSI SULAWESI SELATAN
Authors: Nirwan Nirwan , Syahdan Muhammad , Salim Dafiuddin 
Published: February 2024

Kerusakan terumbu karang diakibatkan dua faktor yakni aktivitas manusia dan proses alami. Aktivitas manusia yang mengancam ekosistem terumbu karang yakni penggunaan bahan peledak, jala tarik, racun dan wisata bahari. Sementara proses alami seperti bleaching, penyakit, pemanansan global, pemangsaan dan eutrofikasi. Salah satu metode yang efektif untuk menentukan tingkat kerusakan terumbu karang yaitu Underwater Photo Transek (UPT) kemudian dianalis menggunakan aplikasi Coral Point Count with Excel extensions (CPCe). Penelitian ini dilaksanakan di perairan daerah wisata bahari Pulau Liukang Loe Kabupaten Bulukumba Provinsi Sulawesi Selatan dengan tujuan untuk mengetahui tingkat dan penyebab kerusakan terumbu karang. Hasil penelitian menunjukkan telah terjadi kerusakan tingkat “Sedang” dengan tutupan rata-rata karang mati pada kedalaman 3 meter 41,47% dan kedalaman 10 meter 38,66%. Kerusakan ini disebabkan berbagai macam aktivitas manusia seperti kegiatan wisata snorkeling dan diving, pengeboman ikan, pelemparan jangkar kapal, dan pembiusan. Adapun kerusakan akibat proses alami yakni penyakit dan pemanasan global.
ANALISIS SEBARAN TINGKAT PENCEMARAN BERDASARKAN METODE INDEKS PENCEMARAN DI MUARA SUNGAI KAPUAS PROVINSI KALIMANTAN TENGAH
Authors: Hayati Norlaila , Baharuddin Baharuddin , Dewi Ira Puspita 
Published: February 2024

Penentuan tingkat pencemaran air dilakukan untuk melakukan pemantauan pencemaran kualitas air. Penelitian ini bertujuan untuk mengetahui sebaran spasial status mutu air dan penentuan tingkat pencemaran di perairan muara Sungai Kapuas berdasarkan metode Indeks Pencemaran. Penelitian ini pada dilaksanakan bulan Juli 2017, pengumpulan data berupa pengambilan sampel kualitas air fisika, kimia dan biologi dengan menggunakan metode Porposiv Sampling dari 13 lokasi sampling, masing-masing nilai parameter diklasifikasikan mengacu pada “Kepmen LH No 51 Tahun 2004 tentang Baku Mutu Air Laut untuk Biota laut” sehingga terbentuk sebaran spasial status mutu air. Tahap berikutnya melakukan analisis data berupa pengisian data dan atribut dari masing-masing parameter dengan mengacu pada “Kepmen LH No 115 Tahun 2003 tentang Pedoman Penentuan Status Mutu Air” sehingga menghasilkan tingkat pencemaran di perairan muara Sungai Kapuas. Sebaran spasial parameter kualitas air yang memenuhi baku mutu diantaranya DO, BOD5, pH. Sedangkan tidak memenuhi baku mutu diantaranya yaitu Suhu, TSS, Kecerahan, Salinitas, Fosfat dan Nitrat. Keadaan fitoplankton di lokasi penelitian mempunyai tingkat keanekaragaman sangat stabil, keseragaman sangat merata dengan kategori sangat baik. Berdasarkan hasil perhitungan Indeks Pencemaran disimpulkan bahwa kondisi perairan Muara Sungai Kapuas tergolong dalam kategori tercemar sedang.