bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gorham Oil Field, Russell County, Kansas
Authors: Walters Robert F. 
Published: January 2025

The 1,397 oil wells in the Gorham oil field have produced nearly 100 million barrels of oil (BO) from 1926 to 1986. Wells were drilled on 10-acre (4-hectare) spacing 660 ft (198 m) apart, within the 50 mi2 (130 km2) oil field. The Arbuckle dolomite (Cambrian-Ordovician) and Reagan Sandstone (Cambrian), a unit reservoir with a strong water drive (original oil-water contact near subsea -1,440 ft), has produced 66% of the oil from porosity under the Pennsylvanian unconformity surface near 3,300 ft (9.90 m). The Lansing-Kansas City (Pennsylvanian) limestone reservoirs have produced 25% of the oil from structural and porosity traps by primary dissolved gas drive and secondary water flooding. A fracture zone in the Topeka limestones (Pennsylvanian) provided the reservoir(s) for spectacular oil recovery of 200,000 BO per well from 30 oil wells. A fourth pay zone yielded gassy, stratigraphically trapped oil from the Tarkio (Pennsylvanian) after fracturing. Precambrian granite and quartzite yield small amounts of oil in 15 wells.
The Gorham oil field is localized by a 10-mi (16-km)-long northwest-trending anticline with 400 ft (120 m) of faulting in the Precambrian granite on the southwest flank. Fault relief diminishes upward with 30 ft (9 m) of closure present in the near-surface Fence-post limestone (Cretaceous). The anticline was defined by the then-unique method of core drilling which provided the location for the discovery well in 1926.
In the 1920's, 1930's, and early 1940's, holes were drilled by the now-obsolete method of cable-tool drilling, providing excellent samples of well cuttings used by the author for acid insoluble residue studies, permitting subdivision of the Arbuckle dolomites into six mapped units. The drilling and development history and the changing role of the petroleum geologist are reviewed with illustrations of cable-tool rigs, derricks, and historic maps.
The adverse environmental effects of.this 60-year-old oil field (444 remaining active oil wells, December 31, 1986) include saline contamination of formerly useful freshwater aquifers and of limited agricultural areas plus slow, long-continued, costly subsidence affecting Interstate Highway 70 (I-70) in three areas. Subsidence rates are diminishing to only one-half foot per year, maximum, in 1986. Subsidence is caused by inadvertent dissolution of the Wellington salt (Permian) at depths of 1,300-1,550 ft (390-465 m) by improperly disposed waste oil-field brines that were unsaturated with regard to salt (halite, NaCl). Stringent regulation by the Kansas Corporation Commission of brine disposal and plugging of abandoned wells is minimizing additional adverse environmental impact.
Heat Flow in the Cretaceous of Northwestern Kansas and Implications for Regional Hydrology
Authors: Förster Andrea , Merriam Daniel F. 
Published: January 2025

Temperature logs are interpreted to investigate the thermal structure of the units overlying the Kansas portion of the Cretaceous Dakota aquifer. The aim of this study is to determine if additional heat input by fluids exists and thus clarify whether the overall conductive heat flow from the basement through the sequence might be overprinted by heat advection. Although interval thermal gradients are determined for different lithologic (stratigraphic) units, the shale thermal gradients are preferred for heat-flow estimation. Shale thermal conductivity as measured in Mesozoic shales in Nebraska and South Dakota is extrapolated to the area because of the similar lithology. A few thermal-conductivity values are determined in sandstone samples of the Dakota Formation and also used in heat-flow estimation. In general, the noncalcareous, marine Cretaceous shales (Pierre, Carlile, Graneros, and Kiowa) show different thermal gradients. Gradients in the Pierre (average value 58.5°C/km) and Carlile (55.5°C/km) are slightly higher than the average gradient in the Graneros Shale (45.1°C/km) and Kiowa Formation (46.5°C/km). The higher thermal gradients are limited to the extreme northwestern corner of the study area where the Pierre and Carlile are present. The heat-flow density of 69-74 mW/m2 observed there is slightly higher than the average of 60 mW/m2 typical for central and eastern Kansas. The higher heat flow observed is in the range of data reported and mapped for northeastern Colorado and the Nebraska Panhandle on the western flank of the Chadron Arch, an area with geothermal overprint by warm fluids. Regional differences in heat flow in western Kansas seemingly are caused by the different composition, porosity, and permeability of the aquifer and the nearness to recharge areas.
Technique for Determining Coccolith Abundance in Shaly Chalk of Greenhorn Limestone (Upper Cretaceous) of Kansas
Authors: Hattin Donald E. , Darko David A. 
Published: January 2025

In samples of shaly chalk from the Greenhorn Limestone, coccolith abundance can be determined by means of a newly devised technique. A known volume of shaly chalk is disaggregated ultrasonically and the resulting sludge suspended in 2000 ml of water. A 0.001-ml aliquot of the suspension is then placed on a slide, dried, and covered. Using a polarizing microscope fitted with a mechanical stage, coccoliths are counted and the number on the slide is used to calculate total number in the suspension. Correction is made for portions of the original sample that did not disaggregate. Chief difficulty is in counting specimens that are clustered together on the slide. Duplicate counts were made for most samples, with results suggesting that the technique is valid.
Shaly chalk samples from a Mitchell County locality contain from 5 x 108 to 6 x 109 coccoliths per cubic centimeter. The lowest values are for samples adjacent to bentonite seams. Coccolith abundance in the Greenhorn samples compares favorably with estimates that have been made for Jurassic limestone of Dorset (England) and Franciscan limestone of California, and with some modern shelf deposits.
Un intruso en el discurso de la realidad: El sueño en El pabellón de las peonías y Sueño en el pabellón rojo
Authors: Espinosa-Campos Lucía 
Published: January 2025

Este artículo compara el papel de los sueños en las obras literarias clásicas de la literatura china El pabellón de las peonías y Sueño en el pabellón rojo, descubriendo patrones recurrentes en la representación de los sueños. A través de la identificación, la enumeración y la descripción de las características de estos patrones similares en la intervención de los sueños en ambas obras, se propone un método de análisis sistemático que permita reconocer y comprender estos rasgos, así como su impacto en el conjunto de cada obra. Por medio del análisis de la influencia de los sueños en el discurso, en los personajes y en el desarrollo de la trama en sí mismo, se explora si estos atienden a un mecanismo específico y si es posible su normalización. Este estudio, desde una perspectiva crítica en el campo de los estudios sinológicos, persigue establecer una base sólida para la comprensión de los sueños en El pabellón de las peonías y Sueño en el pabellón rojo, revelando la riqueza simbólica y narrativa de estos elementos oníricos en la literatura clásica china.
Применение алгоритмов машинного обучения на платформе Hadoop для эффективного анализа и классификации мошеннических операций в банковской сфере
Authors: Лихоузов К.И. 
Published: January 2025

Материалом для исследования послужили последние научные работы в области машинного обучения, больших данных, алгоритмов в этой сфере и финансов. Были применены ряд методов анализа: монографический метод позволил глубоко погрузиться в тему, оценочный – эффективно анализировать данные, а рефлексивный метод дал возможность критически оценить полученные результаты. Использование машинного обучения в финансовых системах является революционным подходом в обнаружении и предотвращении мошенничества. Метод не только решает сложные задачи, связанные с несбалансированными данными и изменчивостью паттернов, но и позволяет обрабатывать информацию с большой скоростью и точностью. В результате применение таких технологий не только улучшает, а кардинально меняет способы защиты финансовых учреждений от мошеннических атак, обеспечивая высокий уровень безопасности для операций и клиентов.
The article uses the latest research work in the field of machine learning, big data, algorithms in this area and financial activities as research material. A number of analytical methods were applied in the process: the monographic method allowed to dive deeply into the topic, the evaluative method allowed effectively analyze the data, and the reflective method allowed to critically evaluate the findings. The use of machine learning in financial systems is a revolutionary approach to fraud detection and prevention. This method not only solves complex problems associated with unbalanced data and pattern variability, but also allows information to be processed with incredible speed and accuracy. As a result, the use of such technologies is not just improving, but revolutionizing the way financial institutions protect themselves from fraudulent attacks, ensuring the highest level of security for operations and customers.
Прогнозирование и оптимизация нового продукта мобильного оператора
Authors: Селивонин А.Е. , Вечерская С.Е. 
Published: January 2025

В статье рассмотрен виртуальный мобильный оператор TeleCom, описана его архитектура. Рассчитано прогнозирование и внедрение чат-бота в архитектуру оператора. Представлен основные моменты по интеграции и масштабируемости чат-бота. Построены графики данных, диаграмма активности чат-бота. Показана значимость прогнозирования и внедрения экспертной системы, которая может успешно функционировать без участия человека-эксперта.
The article considers the virtual mobile operator TeleCom and describes its architecture. The prediction and implementation of a chatbot in the operator’s architecture is calculated. The main points on the integration and scalability of the chatbot are highlighted. Data graphs and a chatbot activity diagram are constructed. The article shows the importance of the expert system forecasting and implementation, which can successfully function without the participation of a human expert.
Astronomische biografieën
Authors: Baneke David 
Published: January 2025

This essay review discusses four biographies of Dutch astronomers: Kapteyn, Oort, De Sitter, and Fockens. The first three are established names from twentieth century astronomy, the fourth is a forgotten, nineteenth-century talent, whose career never got off the ground. Three of the books were written by ‘amateur’ historians. I shall argue that professional historians should appreciate this group, and their efforts, for what they initiate rather than criticize them for what they omit.
Pendidikan Kristen yang Holistik dalam Pembelajaran IPS (Studi Kasus Di Sekolah Menegah Pertama XYZ Lippo Karawaci) [Holistic Christian Education in Social Studies Learning (Case Study at XYZ Lippo Karawaci Junior High School)]
Authors: Purba Rasta Wahyuni , Suwu Selvi Ester 
Published: January 2025

Holistic Christian education covers all aspect of student’s potentials in harmony. In fact education oftens times is seen just from particular aspects, intellectual aspect is considered as the most important. This issue can lead to unablity in maximazing the student’s potentials in other aspects. Learning process in social studies class frequently give boredom to the student, somehow learning become so tighten because of the competition who will have the best grade, it makes student will learn due to the examination period. The researcher found this phenomenon when the researcher was doing observation in learning process. In this research is aimed to research how the XYZ junior high school implements the holistic education in social studies learning. Research method was used in this research was qualitative research, specifically a study case by doing depth interview to the teachers, students’ questionnaire and observation. The result of the research shows that the school already implemented the holistic education but not yet comprehensively and maximally. The supportive aspect in implementing of holistic education is the school program as professional development which helped the teacher in implementing the holistic education and the obstacle which was found in implementing the holistic education is too much content of the material in social studies class with limited time.

ABSTRACT BAHASA INDONESIA: Pendidikan Kristen yang holistik mencakup aspek keseluruhan pribadi siswa sebagai ciptaan yang utuh. Pada kenyataanya pendidikan sering kali dilihat dari salah satu aspek saja, cenderung mengutamakan aspek kognitif sehingga siswa tidak dapat memaksimalkan potensi lainnya. Pembelajaran di dalam kelas khususnya pelajaran IPS seringkali membosankan bahkan menegangkan karena adanya persaingan untuk memperoleh nilai yang paling tinggi, sehingga siswa hanya belajar jika ujian, seperti yang terjadi di sekolah XYZ di Lippo Karawaci khususnya di kelas XI.
Penelitian ini bertujuan untuk mengetahui penerapan pendidikan holistik dalam pembelajaran IPS di sekolah XYZ, serta hal yang menjadi faktor pendukung dan penghambat dalam penerapannya. Metode yang digunakan adalah kualitatif studi kasus dengan menggunakan instrumen, lembar wawancara, lembar observasi dan lembar angket.
Hasil dari penelitian menunjukkan bahwa sekolah ini sudah menerapkan pendidikan yang holistik namun masih ada catatan-catatan yang harus diperhatikan. Hal yang menjadi faktor pendukung dalam penerapan pendidikan yang holistik ialah adanya program Professional development dari sekolah yang membantu guru dalam penerapannya. Kendala yang ditemukan ialah padatnya materi IPS yang diajarkan guru dengan waktu yang terbatas.
Perceptions paysannes de la dynamique des parcours naturels et stratégies d’adaptation dans la vallée du Mandoul au Tchad
Authors: Mabilo Terei Massa , Bechir Ali Brahim , Mama Adi , Oundanang Koussou Mian , Affossogbe Sedjro Antoine Tranquillin , Dossa Luc Hippolyte 
Published: January 2025

Contexte : Dans les pays sahéliens, depuis plus de trois décennies, l’activité pastorale est soumise à des contraintes climatiques et démographiques engendrant une forte dégradation de l’écosystème. Objectif : La présente étude a eu pour objectifs de cerner les perceptions par les éleveurs de la vallée du Mandoul au Tchad des changements climatiques et de leurs incidences sur les pâturages, et de comprendre les stratégies d’adaptation de ces éleveurs. Méthodes : Cette analyse s’est appuyée sur le diagnostic agropastoral. Au total, 205 personnes appartenant à différents groupes d’éleveurs ont été sélectionnés pour cette étude. Cependant, 180 éleveurs ont effectivement participé aux groupes de discussion (focus groups) et 34 autres ont fait objet d’entretiens individuels basés sur un questionnaire préétabli. Résultats : Les résultats ont montré que tous les éleveurs enquêtés perçoivent les changements climatiques à travers la répartition inégale des pluies (88,3 %), une hausse de température (50,5 %) et une plus grande fréquence des vents violents accompagnés de poussières (78,9 %). Ils ont tous déclaré que plusieurs espèces fourragères ont disparu au cours des dix dernières années et que d’autres sont menacées ou en voie de disparition. Ils ont également mentionné l’apparition d’espèces envahissantes de faible valeur pastorale et non appétées par les animaux. Dans ce contexte de vulnérabilité accrue, les stratégies développées par les éleveurs pour leur survie reposent sur la mobilité des troupeaux, la diversification des activités génératrices de revenus et le stockage des résidus de culture pour l’alimentation des animaux pendant la saison sèche. Cependant, selon les éleveurs, ces stratégies ne répondent pas à toutes leurs attentes et montrent des limites, surtout en matière de durabilité. Conclusions : Cette étude fait ressortir la nécessité de la mise en place de stratégies adéquates pour une gestion durable des ressources pastorales dans le Mandoul afin d’assurer la pérennité des espèces végétales tout en soutenant les moyens de subsistance des communautés d'éleveurs.
Pengembangan Video Pembelajaran Interaktif Asking and Offering Help
Authors: Zianadezdha Asfara , Suprayekti Suprayekti , Widyaningrum Retno 
Published: January 2025

Penelitian pengembangan ini bertujuan untuk menghasilkan produk pembelajaran berupa video pembelajaran interaktif Asking and Offering Help untuk peserta didik kelas X di SMA Negeri 62 Jakarta dalam rangka memfasilitasi pembelajaran bahasa Inggris di dalam kelas. Pengembangan video pembelajaran didasarkan pada analisis kebutuhan dan tujuan pembelajaran. Video pembelajaran interaktif merupakan media pembelajaran yang baru dibandingkan dengan media pembelajaran yang sebelumnya digunakan, yaitu media presentasi. Proses pengembangan video pembelajaran interaktif ini menerapkan model pengembangan 4D. Model pengembangan 4D terdiri atas empat tahapan utama, yaitu tahap pendefinisian, tahap desain, tahap pengembangan, dan tahap penyebarluasan. Penelitian pengembangan ini menghasilkan video pembelajaran interaktif yang dapat diakses melalui tautan dan dimuat pada poster. Dalam proses pengembangannya, video pembelajaran interaktif ini telah melalui penilaian ahli media pembelajaran dan ahli materi pelajaran. Dan sudah melalui serangkaian uji coba pengguna, yaitu uji coba one to one, small group, dan field test. Melalui serangkaian proses ini, maka video pembelajaran interaktif adalah media yang dapat digunakan untuk memfasilitasi pembelajaran Asking and Offering Help.
Gasdermins induce the release of mitochondrial DNA during pyroptosis and apoptosis
Authors: de Torre-Minguela Carlos , Gomez Ana , Couillin Isabelle , Pelegrin Pablo 
Published: January 2025

Abstract

Pyroptosis and intrinsic apoptosis are two forms of regulated cell death driven by active caspases where plasma membrane permeabilization is induced by gasdermin pores. Caspase-1 induces gasdermin D pore formation during pyroptosis meanwhile caspase-3 promotes gasdermin E pore formation during apoptosis. These two types of cell death are accompanied by mitochondrial outer membrane permeabilization due to BAK/BAX pore formation in the external membrane of mitochondria, and to some extent this complex also affects the inner mitochondrial membrane facilitating mitochondrial DNA relocalisation from the matrix to the cytosol. However, the detailed mechanism responsible for this process has not been investigated. Herein, we reported that gasdermin processing is required to induce mitochondrial DNA release from cells, despite mitochondrial outer membrane permeabilization, during pyroptosis and apoptosis. Gasdermin targeting the plasma membrane promotes a fast-mitochondrial collapse with the initial accumulation of mitochondrial DNA in the cytosol and then facilitate its release from the cell upon plasma membrane rupture. These findings demonstrate a critical role of gasdermin action on the plasma membrane facilitating the release of mitochondrial DNA as a damage-associated molecular pattern.
Disease exacerbation in MYOrganoids derived from Duchenne Muscular Dystrophy iPSC reveals limitations of microdystrophin therapeutic efficacy
Authors: Albini Sonia , Palmieri Laura , Pili Louna , Jaber Abbass , Hong Ai Vu , Moula Melissa , El-Khoury Riyad , Brochier Guy , Bigot Anne , israeli David , Richard Isabelle 
Published: January 2025

Abstract

Current gene therapy approaches for Duchenne muscular dystrophy (DMD) using AAV-mediated delivery of microdystrophin (µDys) have shown limited efficacy in patients, contrasting with the favorable outcomes observed in animal models. This discrepancy is partly due to the lack of models that replicate key pathogenic features associated with the severity of the human disease, such as fibrosis and muscle dysfunction. To tackle the translational gap, we develop a human disease model that recapitulates these critical hallmarks of DMD for a more predictive therapeutic investigation. Using a muscle engineering approach, we generate MYOrganoids from iPSC-derived muscle cells co-cultured with fibroblasts that enable functional maturation for muscle force analysis upon contractions. Incorporation of DMD fibroblasts within DMD iPSC-derived muscle cells allows phenotypic exacerbation by unraveling of fibrotic signature and fatiguability through cell-contact-dependent communication. Although µDys gene transfer partially restores muscle resistance, it fails to fully restore membrane stability and reduce profibrotic signaling. These findings highlight the persistence of fibrotic activity post-gene therapy in our human DMD system, an unparalleled aspect in existing DMD models, and provide the opportunity to explore the underlying mechanisms of dysregulated cellular communication to identify anti-fibrotic strategies empowering gene therapy efficacy.
Inhibiting DPP4 activity protects hiPSC-derived steatotic HLCs by supporting fatty acid and purine metabolism and dampening inflammation
Authors: Lörch Christiane , Wruck Wasco , Julian Reiss , Adjaye James , Graffmann Nina 
Published: January 2025

Abstract

Background
Metabolic dysfunction-associated steatotic liver disease (MAFLD) has a high prevalence and high co-morbidity for other diseases. Due to the complexity of this multifactorial disease, therapy options are still rather limited. We employed an in vitro pluripotent stem cell-based model to decipher basic disease-associated molecular pathways and to study the mode of action of potential drugs.
Methods
We induced the steatosis phenotype in human induced pluripotent stem cell (iPSC) derived hepatocyte-like cells (HLCs) by oleic acid (OA)-feeding and confirmed regulation of clinically relevant pathways by NGS-based global transcriptomic analyses. Analysis of the secretome of steatotic HLCs revealed Dipeptidyl peptidase 4 (DPP4) as a potential key mediator of the disease. To further elucidate its role in the development of MAFLD, we inhibited DPP4 activity with Vildagliptin (VILDA) and analyzed the global transcriptome changes as well as specific gene and protein expression of steatosis-associated genes with and without DPP4 inhibition.
Results
MAFLD-associated pathways such as PPAR- and TNF signaling were differentially regulated in hiPSC-derived steatotic HLCs. We found increased hepatic DPP4 activity and secretion upon OA. Fatty acid and purine metabolism and inflammation response pathways were improved upon DPP4 inhibition.
Conclusions
Our HLC-model confirmed clinically-relevant association of DPP4 with metabolism and inflammation which foster the development of MAFLD. Inhibiting DPP4 with VILDA partially relieved the steatotic phenotype.
Trial registration
Not applicable
Impact and implications:
Given the difficulties of identifying suitable anti-MAFLD drugs, novel model systems are urgently needed. Our in vitro HLC-model reproduced DPP4-dependent aspects of the disease and responded positively to Vildagliptin treatment. Further elucidation of the role of DPP4 in the etiology of MAFLD is warranted.