bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of moderate-intensity statin with ezetimibe combination vs. high-intensity statin therapy according to sex in patients with atherosclerosis
Authors: Kim Byung Gyu , Lee Seung-Jun , Lee Yong-Joon , You Seng Chan , Hong Soon Jun , Yun Kyeong Ho , Hong Bum-Kee , Heo Jung Ho , Rha Seung-Woon , Hong Sung-Jin , Ahn Chul-Min , Kim Byeong-Keuk , Ko Young-Guk , Choi Donghoon , Hong Myeong-Ki , Jang Yangsoo , Cho Yun-Hyeong , Kim Jung-Sun 
Published: November 2023

AbstractWe aimed to evaluate sex differences in the effects of moderate-intensity statin with ezetimibe combination therapy (rosuvastatin 10 mg plus ezetimibe) versus high-intensity statin (rosuvastatin 20 mg) monotherapy in patients with atherosclerotic cardiovascular disease (ASCVD). This was a sex-specific subgroup analysis of the RACING trial that evaluated the interaction between sex and treatment strategies for the primary outcome (composite of cardiovascular death, major cardiovascular events, or nonfatal stroke at 3 years). Of 3780 patients in the RACING trial, 954 (25.2%) were women. Regardless of sex, the effect of moderate-intensity statin with ezetimibe combination therapy on primary outcome compared with high-intensity statin monotherapy was similar (hazard ratio [HR] 0.98 [0.63–1.52] in women; HR 0.90 [0.71–1.14] in men). The rate of discontinuation or dose reduction of study drugs due to intolerance was lower in the ezetimibe combination group than in the high-intensity statin monotherapy group in both women (4.5% vs. 8.6%, P = 0.014) and men (4.8% vs. 8.0%, P < 0.001). LDL cholesterol levels of < 70 mg/dL at 1, 2, and 3 years were more frequently achieved in the ezetimibe combination group than in the high-intensity statin monotherapy group (all P < 0.001) in both sexes. There were no significant interactions between sex and treatment groups regarding the primary outcome, discontinuation, or dose reduction of study drugs, or the proportion of achievement of LDL cholesterol levels < 70 mg/dL. The effect of ezetimibe combination therapy for the 3-year composite outcomes was not different in both men and women. The benefits of ezetimibe combination therapy on LDL cholesterol lowering and drug tolerance were similarly observed regardless of sex.Trial registration: https://clinicaltrials.gov; Unique identifier: NCT03044665.
Uric acid as a mediator in the correlation between white blood cells and preeclampsia severity: a retrospective cohort study
Authors: Li Bai-jia , Zhu Ting-ting , Hu Xiao-ying , He Chao-man 
Published: November 2023

AbstractThis study aimed to analyze the independent risk factors for predicting preeclampsia severity and explore its underlying mechanism. Clinical data of patients with preeclampsia were collected from the Medical Information Mart for Intensive Care (MIMIC)-IV database. Univariate and multivariate analyses were employed to assess the significant factors associated with preeclampsia severity. Additionally, we performed multivariate logistic regression analysis and mediation analysis to investigate the potential regulatory path. Based on inclusion and exclusion criteria, 731 participants were enrolled: severe preeclampsia (n = 381) and mild to moderate preeclampsia (n = 350). Age, white blood cells (WBC), platelet, creatinine, albumin, uric acid, aspartate aminotransferase, alanine aminotransferase, international normalized ratio, and prothrombin time were significantly related to preeclampsia severity. Besides, hospital length of stay was significantly higher in the severe group. Notably, age and uric acid were independent predictors for preeclampsia severity. Further, WBC and creatinine were significantly associated with uric acid. Finally, the mediation analysis showed that uric acid was a mediator of the relationship between WBC and preeclampsia severity. In conclusion, WBC might affect preeclampsia severity and progression via the mediation of uric acid. This study might provide novel insight into preventing preeclampsia development.
First spectroscopic investigation of anomalous Cepheid variables
Authors: Ripepi V. , Catanzaro G. , Trentin E. , Straniero O. , Mucciarelli A. , Marconi M. , Bhardwaj A. , Fiorentino G. , Monelli M. , Storm J. , De Somma G. , Leccia S. , Molinaro R. , Musella I. , Sicignano T. 
Published: November 2023

Context. Anomalous Cepheids (ACEPs) are intermediate-mass metal-poor pulsators that are mostly discovered in dwarf galaxies of the Local Group. However, recent Galactic surveys, including the Gaia Data Release 3, found a few hundred ACEPs in the Milky Way. Their origin is only poorly understood.
Aims. We aim to investigate the origin and evolution of Galactic ACEPs by studying the chemical composition of their atmospheres for the first time.
Methods. We used UVES at the Very Large Telescope to obtain high-resolution spectra for a sample of nine ACEPs belonging to the Galactic halo. We derived the abundances of 12 elements, C, Na, Mg, Si, Ca, Sc, Ti, Cr, Fe, Ni, Y, and Ba. We complemented these data with literature abundances from high-resolution spectroscopy for an additional three ACEPs that were previously incorrectly classified as type II Cepheids. This increased the sample to a total of 12 stars.
Results. All the investigated ACEPs have an iron abundance [Fe/H] < −1.5 dex, as expected from theoretical predictions for these pulsators. The abundance ratios of the different elements to iron show that the chemical composition of ACEPs is generally consistent with that of the Galactic halo field stars, with the exception of sodium, which is found to be overabundant in 9 out of the 11 ACEPs where it was measured. This is very similar to the situation for second-generation stars in Galactic globular clusters. The same comparison with dwarf and ultra-faint satellites of the Milky Way reveals more differences than similarities. It is therefore unlikely that the bulk of Galactic ACEPs originated in a galaxy like this that subsequently dissolved into the Galactic halo. The principal finding of this work is the unexpected overabundance of sodium in ACEPs. We explored several hypotheses to explain this feature, finding that the most promising scenario is the evolution of low-mass stars in a binary system with either mass transfer or merging. Detailed modelling is needed to confirm this hypothesis.
Polyphenols, Antioxidants, and Wound Healing of Lecythis pisonis Seed Coats
Authors: Pimentel Elisângela Flávia , de Oliveira Bruno Gomes , Pereira Ana Claudia Hertel , Figueira Mariana Moreira , Portes Danielle Braga , Scherer Rodrigo , Ruas Fabiana Gomes , Romão Wanderson , Fronza Márcio , Endringer Denise Coutinho 
Published: November 2023

AbstractTo better use the Lecythis pisonis Cambess. biomass, this study investigates whether Sapucaia seed coats present wound healing properties. We analyzed the antibacterial, antioxidant,
and wound healing-promoting potentials, plus cytotoxicity and stimulation of vascular endothelial growth factor-A. The chemical composition was analyzed by positive ion mode electrospray
ionization Fourier transform ion cyclotron resonance mass spectrometry. A total of 19 compounds were identified, such as proanthocyanidin A1, procyanidins A1, B2, and C1, epigallocatechin,
and kaempferol (p-coumaroyl) glycoside. Potent antioxidant strength/index was verified for 2,2-diphenyl-1-picrylhydrazyl radical (IC50 = 0.99 µg/mL) and ferric reducing
antioxidant power (IC50 = 1.09 µg/mL). The extract did not present cytotoxicity and promoted significant cell migration and/or proliferation of fibroblasts (p < 0.05). Vascular
endothelial growth factor-A was stimulated dose-dependently at 6 µg/mL (167.13 ± 8.30 pg/mL), 12.5 µg/mL (210.3 ± 14.2 pg/mL), and 25 µg/mL (411.6 ± 29.4 pg/mL). Platelet-derived growth
factor (PDGF) (0.002 µg/mL) was stimulated at 215.98 pg/mL. Staphylococcus aureus was susceptible to the extract, with a minimum inhibitory concentration of 31.25 µg/mL. The
identified compounds benefit the antioxidant activity, promoting hemostasis for the wound healing process, indicating that this extract has the potential for use in dermatological
cosmetics.
Facilitated Synthetic Access to Boronic Acid-Modified Nucleoside Triphosphates and Compatibility with Enzymatic DNA Synthesis
Authors: Niogret Germain , Röthlisberger Pascal , Hollenstein Marcel , Levi-Acobas Fabienne , Bonhomme Frédéric , Gasser Gilles 
Published: November 2023

AbstractDecorating nucleic acids with boronic acids can extend the usefulness of oligonucleotide-based tools to the development of medical imaging agents, the promotion of binding of aptamers to markedly more challenging targets, or the detection of (poly)saccharides. However, due to the hygroscopic nature and high intrinsic reactivity of boronic acids, protocols for their introduction into nucleic acids are scarce. Here, we have explored various synthetic routes for the crafting of nucleoside triphosphates equipped with phenylboronic acids. Strain-promoted azide–alkyne cycloaddition appears to be the method of choice for this purpose and it enabled us to prepare a modified nucleotide. Enzymatic DNA synthesis permitted the introduction of up to thirteen boronic acid residues in oligonucleotides, which bodes well for its extension to SELEX and related methods of in vitro selection of functional nucleic acids.
The influence of the Chinese Cinderella (“Yeh-Shen”) on the evolving image of Cinderella in the West
Authors: Ou Peiyi , Zhang Xiaohong 
Published: November 2023

AbstractTaking Cinderella as an evolving image across cultures, this article compares the image of Yeh-Shen in major English translations to those of Cinderella in the Western classics of Giambattista Basile, Charles Perrault, the Brothers Grimm, and Disney. The study incorporates a comparison of the story types and the protagonists’ family backgrounds, social statuses, and personalities in constructing the evolving image of Cinderella. It is argued that the widely acknowledged story genealogy of “Basile–Perrault–the Brothers Grimm–Disney” is questionable in terms of the phenomenon of Cinderella “becoming of the people’s princess”. Evidence found in both reader acceptance and postmodernist rewritings supports the hypothesis that the story of Yeh-Shen has had a substantial influence on the evolving image of Cinderella. The analysis of its English translation and acceptance from a comparative perspective brings to light the continued legacy of the literary image of Yeh-Shen, illustrates the esthetic complexity and possibilities of image translation, and most importantly, reveals the rich roots of postmodernist themes contained in the Chinese tale that has long influenced the West.
“May the path never close”
Authors: Abbasi Pyeaam , Mousavi Maryamossadat 
Published: November 2023

Abstract
Resistance to postcolonial oppressive ideologies assumes significance within Chinua Achebe’s Anthills of the Savannah (1987), portraying predicaments of a post-independence fictional African state of Kangan. Drawing on the Deleuze-Guattarian “ontology of becoming”, “rhizome”, “nomad thought”, distinction of “striated” and “smooth” spaces, their account of the “State Apparatus” and the “war machine”, and “assemblage”, the study demonstrates how Achebe entertains possibilities of convergence with their philosophy. It displays how the Kangan people, while engaging in “ontology of becoming”, strive to deterritorialise themselves from Sam’s State that attempts to define their subjectivity. Concurrently, Sam’s State implements varieties of schemes to re-subjugate its subjects under its territorial authority. The study concludes how the war machine’s menacing force eventually destabilises the whole “State Apparatus”.
‘Narrative structure’, ‘rhetorical structure’, ‘text structure’
Authors: Tincheva Nelly 
Published: November 2023

Abstract
The paper seeks to provide a cognitive-linguistic re-interpretation of the centuries-old notion of whole-text structure. The investigation presented here draws on 317 data sources selected through a scoping literature review. The paper demonstrates how text structure, narrative structure, rhetorical structure, etc. all represent metonymically one and the same multi-faceted underlying concept. That concept is argued to result from the amalgamated operation of conceptual metaphor and conceptual metonymy combined with the simultaneous and dynamic operation of (what are known in gestalt psychology as) profiling shifts. The paper further demonstrates how such shifts in profiling operate on text-worlds and discourse-worlds to bring about perceptions of a text’s ‘progression’ and of whole-text structure.
Speaking about knowledge
Authors: Aikhenvald Alexandra Y. 
Published: November 2023

AbstractWe focus on the grammatical expression of four major groups of meanings related to knowledge: I. Evidentiality: grammatical expression of information source; II. Egophoricity: grammatical expression of access to knowledge; III. Mirativity: grammatical expression of expectation of knowledge; and IV. Epistemic modality: grammatical expression of attitude to knowledge. The four groups of categories interact. Some develop overtones of the others. Epistemic-directed evidentials have additional meanings typical of epistemic modalities, while egophoricity-directed evidentials combine some reference to access to knowledge by speaker and addressee. Over the past thirty years, new evidential choices have evolved among the Tariana – whose language has five evidential terms in an egophoricity-directed system – to reflect new ways of acquiring information, including radio, television, phone, and internet. Evidentials stand apart from other means of knowledge-related categories as tokens of language ecology corroborated by their sensitivity to the changing social environment.
A direct sampling-based deep learning approach for inverse medium scattering problems
Authors: Ning Jianfeng , Han Fuqun , Zou Jun 
Published: November 2023

Abstract
In this work, we focus on the inverse medium scattering problem (IMSP), which aims to recover unknown scatterers based on measured scattered data. Motivated by the efficient direct sampling method (DSM) introduced in Ito et al (2012 Inverse Problems
28 025003), we propose a novel direct sampling-based deep learning approach (DSM-DL) for reconstructing inhomogeneous scatterers. In particular, we use the U-Net neural network to learn the relation between the index functions and the true contrasts. Our proposed DSM-DL is computationally efficient, robust to noise, easy to implement, and able to naturally incorporate multiple measured data to achieve high-quality reconstructions. Some representative tests are carried out with varying numbers of incident waves and different noise levels to evaluate the performance of the proposed method. The results demonstrate the promising benefits of combining deep learning techniques with the DSM for IMSP.
The MLE is a reliable source: sharp performance guarantees for localization problems
Authors: Munier Nathanaël , Soubies Emmanuel , Weiss Pierre 
Published: November 2023

Abstract
Single source localization from low-pass filtered measurements is ubiquitous in optics, wireless communications and sound processing. We analyze the performance of the maximum likelihood estimator (MLE) in this context with additive white Gaussian noise. We derive necessary conditions and sufficient conditions on the maximum admissible noise level to reach a given precision with high probability. The two conditions match closely, with a discrepancy related to the conditioning of a noiseless cost function. They tightly surround the Cramér–Rao lower bound for low noise levels. However, they are significantly more precise to describe the performance of the MLE for larger levels. As an outcome, we obtain a new criterion for the design of point spread functions in single molecule microscopy.
The effect of intrinsic strain on the thermal expansion behavior of Janus MoSSe nanotubes: a molecular dynamic simulation
Authors: Zhang Run-Sen , Yin Xiang-Lei , Zhang Yu-Long , Jiang Jin-Wu 
Published: November 2023

Abstract
In this study, we conducted molecular dynamic simulations to investigate the thermal expansion behavior of Janus MoSSe nanotubes. We focused on understanding how the intrinsic strain in these nanotubes affects their thermal expansion coefficient (TEC). Interestingly, we found that Janus MoSSe nanotubes with sulfur (S) on the outer surface (MoSeS) exhibit a different intrinsic strain compared to those with selenium (Se) on the outer surface (MoSSe). In light of this observation, we explored the influence of this intrinsic strain on the TEC of the nanotubes. Our results revealed distinct trends for the TEC along the radial direction (TEC-r) and the axial direction (TEC-l

x
) of the MoSSe and MoSeS nanotubes. The TEC-r of MoSeS nanotubes was found to be significantly greater than that of MoSSe nanotubes. Moreover, the TEC-l

x
of MoSeS nanotubes was smaller than that of MoSSe nanotubes. Further analysis showed that the TEC-r of MoSeS nanotubes decreased by up to 37% as the radius increased, while that of MoSSe nanotubes exhibited a slight increase with increasing radius. On the other hand, the TEC-l

x
of MoSeS nanotubes increased by as much as 45% with increasing radius, whereas that of MoSSe nanotubes decreased gradually. These opposite tendencies of the TECs with respect to the radius were attributed to the presence of intrinsic strain within the nanotubes. The intrinsic strain was found to play a crucial role in inducing thermally induced bending and elliptization of the nanotubes’ cross-section. These effects are considered key mechanisms through which intrinsic strain influences the TEC. Overall, our study provides valuable insights into the thermal stability of Janus nanotubes. By understanding the relationship between intrinsic strain and the thermal expansion behavior of nanotubes, we contribute to the broader understanding of these materials and their potential applications.
Poisson problems involving fractional Hardy operators and measures
Authors: Chen Huyuan , Gkikas Konstantinos T , Nguyen Phuoc-Tai 
Published: November 2023

Abstract
In this paper, we study the Poisson problem involving a fractional Hardy operator and a measure source. The complex interplay between the nonlocal nature of the operator, the peculiar effect of the singular potential and the measure source induces several new fundamental difficulties in comparison with the local case. To overcome these difficulties, we perform a careful analysis of the dual operator in the weighted distributional sense and establish fine properties of the associated function spaces, which in turn allow us to formulate the Poisson problem in an appropriate framework. In light of the close connection between the Poisson problem and its dual problem, we are able to establish various aspects of the theory for the Poisson problem including the solvability, a priori estimates, variants of Kato’s inequality and regularity results.
Corrigendum: Multi-temperature generalized Zhdanov closure for scrape-off layer/edge applications (2022 Plasma Phys. Control. Fusion
64 045005)
Authors: Raghunathan M , Marandet Y , Bufferand H , Ciraolo G , Ghendrih Ph , Tamain P , Serre E 
Published: November 2023

Abstract
Corrigendum for the manuscript (Raghunathan et al 2022 Plasma Phys. Control. Fusion
64 045005).
α-In2Se3/Nb-doped MoSh2 heterojunction: a first-principles study
Authors: Lv Xiurui , Liu Guipeng , Mao Bangyao , Huang Heyuan , Zhao Guijuan , Yang Jianhong 
Published: November 2023

Abstract
The α-In2Se3 material is a two-dimensional ferroelectric semiconductor whose structural asymmetry gives it spontaneous polarization properties, and exhibits a direct bandgap structure when it is multilayered. α-In2Se3 is an n-type semiconductor, which is usually used in experiments to form heterojunctions with p-type semiconductors to prepare photodetectors. In this paper, we designed α-In2Se3/Nb-doped MoS2 heterojunction, because Nb doping is a good p-type dopant for MoS2. Our research shows that: the heterojunction exhibits type-Ⅱ band alignment; the band offset can be changed by the out-of-plane polarization direction; doping can modulate the Fermi energy level position of MoS2 and thus further modulate the band alignment and band offset. The α-In2Se3/Nb-doped MoS2 heterojunction is expected to be applied to the field of photodetectors, and we proposed a method to adjust the band alignment of the heterojunction by adjusting the doping concentrations.
Temperature dependence of transport critical current density for REBCO superconducting tapes deposited by MOCVD
Authors: Wang Qianfu , Jiang Ping , Li Meng , Zhao Yaoyao , Zhang Shudong , Zhang Xuefeng , Chen Yimin 
Published: November 2023

Abstract
The temperature-dependent transport critical current density (

J

c

) behavior of REBa2Cu3O7−δ
(REBCO) superconducting tapes with various RE substitutions and combinations has been systematically studied in the temperature range of 4 K–77 K. The measured

J

c

values were found to be highly in accordance with

J

c

T
,
B

=

J

c

(
0

K

,
B
)
(
1
−
T

/

T

c

)

s

with the values of the exponent coefficients s ranging from 1.9 to 2.6 in the magnetic-field range of 1–5 T depending on RE ion(s), revealing the dominative pinning mechanism of flux core pinning. The RE-ionic-radius (r) dependences of

J

c

T
,
B

showed reversed trends for temperatures below and above 50 K, with

J

c

increasing with r at higher temperatures while it decreased with r at lower temperatures, which was consistent with previously reported results. In particular, the in-field

J

c

of REBCO tapes at 4 K as a function of r was consistent with the

J

c

–r trend for low temperatures. We propose to attribute the

J

c

–r trends to the higher charge carrier density and the lower critical transition temperature (

T

c

) in REBCO films with smaller r. The Gd0.5Yb0.5BCO tape with superior

J

c

at low temperatures exhibited the furthest diversion from the

J

c

–r trendlines due to enhanced correlated pinning by the high-density of vertically aligned second-phase nanocolumns in the film. The temperature dependence of

J

c

for REBCO tapes with a larger r was found to be more susceptible to the magnetic field. Meanwhile, the exponent coefficients s showed a more precipitous increase with the increasing magnetic field, partially due to the lack of effective pinning defects, which was also confirmed by the two-dimensional x-ray diffraction patterns and the higher α values. This work contributes to the study of the

J

c

of REBCO superconducting tapes below 20 K and leads to a deeper understanding of the temperature-dependent

J

c

behavior of REBCO films with various RE substitutions and combinations. This provides more comprehensive guidelines for the optimization of RE ions in REBCO for applications at specific temperatures and magnetic fields.
A novel heater-triggered HTS semi-persistent current switch with high switching-off resistance
Authors: Tan Haowen , Huang Zhen 
Published: November 2023

Abstract
A semi-persistent current switch (semi-PCS) with a simple fabrication process, high switching-off resistance, and minimal power dissipation during operation is required to realize the semi-persistent mode in a high-temperature superconducting (HTS) magnet. In this study, a semi-PCS with high switching-off resistance was developed by optimizing the HTS tape structure in a heater-triggered semi-PCS. This optimization was achieved by selectively removing a portion of the conductive and superconducting layers on the surface and edges of the HTS tapes. The microstructure of the treated HTS tape was then analyzed. The resistance of the semi-PCS in a non-superconducting state was measured, and it was connected to an insulated coil for performance testing. To further evaluate its impact, an equivalent electrical circuit model was developed and used to predict the effect of the semi-PCS when applied to a larger superconducting coil. Furthermore, the study explored the impact of the excitation rates on the power dissipation and heat generation of the semi-PCS.