bluuebunny/crossref_metadata_2025_split huggingface dataset:
JWST Reveals Excess Cool Water near the Snow Line in Compact Disks, Consistent with Pebble Drift
Authors: Banzatti Andrea , Pontoppidan Klaus M. , Carr John S. , Jellison Evan , Pascucci Ilaria , Najita Joan R. , Muñoz-Romero Carlos E. , Öberg Karin I. , Kalyaan Anusha , Pinilla Paola , Krijt Sebastiaan , Long Feng , Lambrechts Michiel , Rosotti Giovanni , Herczeg Gregory J. , Salyk Colette , Zhang Ke , Bergin Edwin A. , Ballering Nicholas P. , Meyer Michael R. , Bruderer Simon ,   The JDISCS Collaboration
Published: November 2023

Abstract
Previous analyses of mid-infrared water spectra from young protoplanetary disks observed with the Spitzer-IRS found an anticorrelation between water luminosity and the millimeter dust disk radius observed with ALMA. This trend was suggested to be evidence for a fundamental process of inner disk water enrichment proposed decades ago to explain some properties of the solar system, in which icy pebbles drift inward from the outer disk and sublimate after crossing the snow line. Previous analyses of IRS water spectra, however, were uncertain due to the low spectral resolution that blended lines together. We present new JWST-MIRI spectra of four disks, two compact and two large with multiple radial gaps, selected to test the scenario that water vapor inside the snow line is regulated by pebble drift. The higher spectral resolving power of MIRI-MRS now yields water spectra that separate individual lines, tracing upper level energies from 900 to 10,000 K. These spectra clearly reveal excess emission in the low-energy lines in compact disks compared to large disks, demonstrating an enhanced cool component with T ≈ 170–400 K and equivalent emitting radius R
eq ≈ 1–10 au. We interpret the cool water emission as ice sublimation and vapor diffusion near the snow line, suggesting that there is indeed a higher inward mass flux of icy pebbles in compact disks. Observation of this process opens up multiple exciting prospects to study planet formation chemistry in inner disks with JWST.
Little Red Dots or Brown Dwarfs? NIRSpec Discovery of Three Distant Brown Dwarfs Masquerading as NIRCam-selected Highly Reddened Active Galactic Nuclei
Authors: Langeroodi Danial , Hjorth Jens 
Published: November 2023

Abstract
Cold, substellar objects such as brown dwarfs have long been recognized as contaminants in color-selected samples of active galactic nuclei (AGNs). In particular, their near- to mid-infrared colors (1–5 μm) can closely resemble the V-shaped (f

λ
) spectra of highly reddened accreting supermassive black holes (“little red dots”), especially at 6 < z < 7. Recently, a NIRCam-selected sample of little red dots over 45 arcmin2 has been followed up with deep NIRSpec multiobject prism spectroscopy through the UNCOVER program. By investigating the acquired spectra, we identify 3 of the 14 followed-up objects as T/Y dwarfs with temperatures between 650 and 1300 K and distances between 0.8 and 4.8 kpc. At

4.8

−
0.1

+
0.6

kpc, A2744-BD1 is the most distant brown dwarf discovered to date. We identify the remaining 11 objects as extragalactic sources at z
spec ≳ 5. Given that three of these sources are strongly lensed images of the same AGN (A2744-QSO1), we derive a brown dwarf contamination fraction of 25% in this NIRCam selection of little red dots. We find that in the near-infrared filters, brown dwarfs appear much bluer than the highly reddened AGN, providing an avenue for distinguishing the two and compiling cleaner samples of photometrically selected highly reddened AGN.
Soins par Acupression auriculaire® dispensés chez une patiente hospitalisée en soins palliatifs d’oncologie
Authors: Huyen Nguyen Thuy 
Published: November 2023

Un soin par acupression auriculaire® en vue de soulager des douleurs neuropathiques au membre inférieur droit a été réalisé chez une patiente de 41 ans hospitalisée en oncologie pour une récidive d’un mélanome. La séance de soins a eu comme effet inattendu une libération des selles au bout de 10 minutes. Les effets, en fin de séance, ont été multiples : soulagement de la douleur, levée de la constipation et une détente ressentie et exprimée par la patiente. L’acupression auriculaire® a été une aide pour cette patiente en soins palliatifs en termes d’amélioration de sa qualité de vie.
84 , revue indifférente
Authors: Baillaud Bernard 
Published: November 2023

J’ai choisi pour qualifier la revue 84 le mot le moins approprié : revue indifférente . Animée d’une main de feu par Marcel Bisiaux, secondé par Henri Thomas, Alfred Kern et André Dhôtel, relayés par Georges Lambrichs, la revue 84 résulte de deux logiques. La première est individuelle et comprend les figures tutélaires de Gide, Artaud et Paulhan. La seconde relève des groupes qu’elle agrège provisoirement : le Grand Jeu et le Collège de’Pataphysique, le surréalisme. Deux éditeurs se la disputent, Minuit pour la reprendre, Gallimard pour en absorber les forces individuelles. Déjà esquissées avant la création de la revue, les lignes individuelles tracées par les auteurs de 84 se poursuivront après sa disparition. Chacun de ses noms portant avec lui contradictions et complexités, l’ensemble apparaît comme un étoilement particulièrement riche. C’est cette complexité des figures qui fait l’intérêt de la revue.
La fabrique discursive de la haine
Authors: Voirol Olivier , Martini Émilie 
Published: November 2023

Face à la prolifération des discours de haine en ligne, la réponse la plus courante est celle de la modération des contenus, de la régulation de la parole et de l’élaboration de protocoles numériques visant à repérer et exclure de façon automatisée les énoncés haineux. Le présent texte propose de remonter en amont de ce processus en examinant la manière dont les discours de haine transfigurent des affects réels en leur impulsant une trajectoire spécifique par la fabrication d’un objet de haine. Sur la base d’un corpus de discours d’« agitateurs de la toile » officiant sur Youtube, l’analyse montre que ces discours procèdent à une excitation des affects, un détournement de ces derniers et un évitement du monde objectif. La disparition du monde, doublée de la haine de cibles précises, caractérise cette trajectoire de la haine propre à une « politique du ressentiment » aux antipodes de l’agir démocratique. Le propre de ce dernier est, en effet, de transfigurer les affects en objets discursifs constituant la base d’un monde troublé appelé à devenir l’objet de délibérations au sein de l’espace public. Une autre réponse à la prolifération des discours de haine est, par conséquent, de faire fructifier les conditions matérielles et sociales permettant de « prendre soin » et d’étendre l’espace public d’expérience, d’enquête et de délibération.
Technicisation des registres de vote et participation matérielle au cameroun
Authors: Eyenga Georges Macaire 
Published: November 2023

Les réflexions sur la biométrie électorale en Afrique ont eu sur cette technologie un regard critique soulignant les logiques de son adoption à l’échelle du continent et les limites de sa mise en œuvre dans les processus électoraux. Le présent texte poursuit cette histoire des techniques, mais en décentrant la focale d’analyse sur la technicisation et la participation matérielle dont cette technologie est porteuse. À partir d’une étude menée à Yaoundé auprès d’Elections Cameroon, le texte analyse la manière dont la biométrie utilisée pour la constitution d’un registre de vote sécurisé et fiable, a été investie comme un mode d’engagement sur la question démocratique. Ce faisant, il s’inscrit au sein du « tournant matériel » pour saisir les qualités politiques de la biométrie, sa construction sociale et son rôle en tant que participant notable à l’utopie démocratique. L’analyse s’ancre dans les travaux de Noortje Marres sur les modalités contemporaines de la participation qui, au-delà d’informer les citoyens des problèmes publics, s’oriente de plus en plus vers une transformation des pratiques matérielles de la vie quotidienne. Il ressort de cette étude que, loin d’être une condition préalable de la démocratie, la biométrie électorale est perçue par certains acteurs comme une « technologie d’engagement » dont l’agence lui permet de s’assembler aux autres technologies de participation pour rendre agile les opérations d’enregistrement des électeurs et résoudre certaines controverses liées à l’organisation d’élections libres et transparentes.
Figures de l’ironie et thématiques politiques dans le streaming de jeu vidéo sur Twitch.tv : approche rhétorique des performances d’Antoine Daniel
Authors: Barnabé Fanny 
Published: November 2023

Cet article propose d’étudier, depuis une perspective rhétorique, les formes et fonctions pragmatiques de l’ironie employée par les streamers de jeux vidéo sur la plateforme Twitch.tv à travers une étude de cas : l’articulation des figures ironiques et des thématiques politiques dans les performances du streamer Antoine Daniel. L’article part de l’hypothèse que l’ironie peut servir la mise en spectacle du jeu (activité déjà caractérisée par son « second degré » ; Henriot, 1989 : 279), être le support de sa remédiation sur une plateforme de diffusion audiovisuelle, et qu’en retour l’attitude ludique du streamer n’est pas sans effet sur les modes d’expression de l’ironie et du discours critique qu’elle est censée porter. Sur la base d’un corpus de 127 vidéos de « best of » archivées sur YouTube et reprenant les temps forts des diffusions d’Antoine Daniel sur Twitch.tv , nous détaillons quatre grands types de fonctions pragmatiques exercées par l’ironie dans le contexte du streaming : la production d’incertitude, la narration, l’effacement énonciatif et la production de sociabilité (tantôt sous forme coopérative, tantôt comme jeu de sabotage).
Fonctionnement textuel des syntagmes nominaux démonstratifs appositifs
Authors: Tritar-Ben Ahmed Saloua 
Published: November 2023

La présente contribution se propose de focaliser l’intérêt sur la catégorie des syntagmes nominaux appositifs comportant des déterminants démonstratifs en les inscrivant dans une double opposition : celle, d’une part, entre les syntagmes nominaux démonstratifs appositifs spécifiques et les génériques, et celle, d’autre part, entre les syntagmes nominaux démonstratifs appositifs mémoriels spécifiques et leurs pendants génériques. Cette double opposition relative au fonctionnement des syntagmes nominaux démonstratifs appositifs est saisie dans un cadre textuel, en l’occurrence l’œuvre romanesque d’H. de Balzac, Le Lys dans la vallée , et se focalise sur leur rôle énonciatif dans le discours en tant que foyer du point de vue – au sens narratologique et axiologique du terme – à travers l’analyse de leurs cotextes et de leurs supports.
Corneal Higher Order Aberrations and Epithelial Remodeling With Femtosecond Laser–Assisted LASIK Topography-guided and Customized Asphericity Ablation in the Contralateral Eye: A Randomized, Double-Blind, Prospective Study
Authors: Lyra Adriana F.V. , Alves Ermano M. , Montenegro Afra A. , Parente Natália S. , Cardoso Manuela T. , Alves Lucas M. , Maia Carolina B. , Fontes Bruno M. , Nose Walton 
Published: November 2023

Purpose:
To evaluate refractive results, corneal higher order aberrations (HOAs), and epithelial remodeling in the preoperative and postoperative period of regular corneas that had topography-guided femtosecond laser–assisted laser in situ keratomileusis (LASIK) (Contoura WaveLight; Alcon Laboratories, Inc) and compare them with the contralateral eye that underwent ablation customized by asphericity (Custom-Q WaveLight; Alcon Laboratories, Inc) in myopic eyes with or without astigmatism.

Methods:
A prospective, randomized, and double-blind study was conducted. Patients underwent preoperative and postoperative epithelial mapping and corneal tomography to assess the epithelial thickness map, HOAs of the corneal anterior surface, visual acuity, and refractive evaluation.

Results:

This study enrolled 96 normal eyes of 48 patients. Uncorrected distance visual acuity of 20/20 or better was achieved in 97% of patients and gains in corrected distance visual acuity and effectiveness in correcting refractive astigmatism were similar in both techniques. Seventeen sectors of the corneal epithelium map were assessed by spectral-domain optical coherence tomography and no significant differences were found between techniques preoperatively and postoperatively (
P
> .05). HOA root mean square, coma Z
3
±1
, trefoil Z
3
−
3
, and tissue consumption exhibited statistically significant between-technique differences (
P
< .05).

Conclusions:

The Contoura and Custom-Q techniques were similar with respect to refractive and visual outcomes after 3 months, as well as in epithelial remodeling. The Contoura provides lower postoperative HOA root mean square, coma Z
3
±1
, and trefoil Z
3
−
3
values, but the techniques showed no differences in the correction of the corneal astigmatic wavefront component and in the spherical aberration after 3 months.

[
J Refract Surg
. 2023;39(11):751–758.]
Homer1a reduces inflammatory response after retinal ischemia/reperfusion injury
Authors: Dou Yanan , Fei Xiaowei , He Xin , Huan Yu , Wei Jialiang , Wu Xiuquan , Lyu Weihao , Fei Zhou , Li Xia , Fei Fei 
Published: November 2023

Abstract

JOURNAL/nrgr/04.03/01300535-202407000-00042/figure1/v/2023-11-20T171125Z/r/image-tiff

Elevated intraocular pressure (IOP) is one of the causes of retinal ischemia/reperfusion injury, which results in NLRP3 inflammasome activation and leads to visual damage. Homer1a is reported to play a protective role in neuroinflammation in the cerebrum. However, the effects of Homer1a on NLRP3 inflammasomes in retinal ischemia/reperfusion injury caused by elevated IOP remain unknown. In our study, animal models were constructed using C57BL/6J and Homer1flox/
–/Homer1a+/
–/Nestin-Cre+/
– mice with elevated IOP-induced retinal ischemia/reperfusion injury. For in vitro experiments, the oxygen-glucose deprivation/reperfusion injury model was constructed with Müller cells. We found that Homer1a overexpression ameliorated the decreases in retinal thickness and Müller cell viability after ischemia/reperfusion injury. Furthermore, Homer1a knockdown promoted NF-κB P65Ser536 activation via caspase-8, NF-κB P65 nuclear translocation, NLRP3 inflammasome formation, and the production and processing of interleukin-1β and interleukin-18. The opposite results were observed with Homer1a overexpression. Finally, the combined administration of Homer1a protein and JSH-23 significantly inhibited the reduction in retinal thickness in Homer1flox/
–/Homer1a+/
–/Nestin-Cre+/
– mice and apoptosis in Müller cells after ischemia/reperfusion injury. Taken together, these studies demonstrate that Homer1a exerts protective effects on retinal tissue and Müller cells via the caspase-8/NF-κB P65/NLRP3 pathway after I/R injury.
Lactate: a prospective target for therapeutic intervention in psychiatric disease
Authors: Cai Yanhui , Guo Haiyun , Han Tianle , Wang Huaning 
Published: November 2023

Abstract
Although antipsychotics that act via monoaminergic neurotransmitter modulation have considerable therapeutic effect, they cannot completely relieve clinical symptoms in patients suffering from psychiatric disorders. This may be attributed to the limited range of neurotransmitters that are regulated by psychotropic drugs. Recent findings indicate the need for investigation of psychotropic medications that target less-studied neurotransmitters. Among these candidate neurotransmitters, lactate is developing from being a waste metabolite to a glial-neuronal signaling molecule in recent years. Previous studies have suggested that cerebral lactate levels change considerably in numerous psychiatric illnesses; animal experiments have also shown that the supply of exogenous lactate exerts an antidepressant effect. In this review, we have described how medications targeting newer neurotransmitters offer promise in psychiatric diseases; we have also summarized the advances in the use of lactate (and its corresponding signaling pathways) as a signaling molecule. In addition, we have described the alterations in brain lactate levels in depression, anxiety, bipolar disorder, and schizophrenia and have indicated the challenges that need to be overcome before brain lactate can be used as a therapeutic target in psychopharmacology.
Functional near-infrared spectroscopy in non-invasive neuromodulation
Authors: Huo Congcong , Xu Gongcheng , Xie Hui , Chen Tiandi , Shao Guangjian , Wang Jue , Li Wenhao , Wang Daifa , Li Zengyong 
Published: November 2023

Abstract
Non-invasive cerebral neuromodulation technologies are essential for the reorganization of cerebral neural networks, which have been widely applied in the field of central neurological diseases, such as stroke, Parkinson's disease, and mental disorders. Although significant advances have been made in neuromodulation technologies, the identification of optimal neurostimulation parameters including the cortical target, duration, and inhibition or excitation pattern is still limited due to the lack of guidance for neural circuits. Moreover, the neural mechanism underlying neuromodulation for improved behavioral performance remains poorly understood. Recently, advancements in neuroimaging have provided insight into neuromodulation techniques. Functional near-infrared spectroscopy, as a novel non-invasive optical brain imaging method, can detect brain activity by measuring cerebral hemodynamics with the advantages of portability, high motion tolerance, and anti-electromagnetic interference. Coupling functional near-infrared spectroscopy with neuromodulation technologies offers an opportunity to monitor the cortical response, provide real-time feedback, and establish a closed-loop strategy integrating evaluation, feedback, and intervention for neurostimulation, which provides a theoretical basis for development of individualized precise neurorehabilitation. We aimed to summarize the advantages of functional near-infrared spectroscopy and provide an overview of the current research on functional near-infrared spectroscopy in transcranial magnetic stimulation, transcranial electrical stimulation, neurofeedback, and brain-computer interfaces. Furthermore, the future perspectives and directions for the application of functional near-infrared spectroscopy in neuromodulation are summarized. In conclusion, functional near-infrared spectroscopy combined with neuromodulation may promote the optimization of central neural reorganization to achieve better functional recovery from central nervous system diseases.
A “messenger zone hypothesis” based on the visual three-dimensional spatial distribution of motoneurons innervating deep limb muscles
Authors: Huang Chen , Wang Shen , Deng Jin , Gu Xinyi , Guo Shuhang , Yin Xiaofeng 
Published: November 2023

Abstract

JOURNAL/nrgr/04.03/01300535-202407000-00036/figure1/v/2023-11-20T171125Z/r/image-tiff

Coordinated contraction of skeletal muscles relies on selective connections between the muscles and multiple classes of the spinal motoneurons. However, current research on the spatial location of the spinal motoneurons innervating different muscles is limited. In this study, we investigated the spatial distribution and relative position of different motoneurons that control the deep muscles of the mouse hindlimbs, which were innervated by the obturator nerve, femoral nerve, inferior gluteal nerve, deep peroneal nerve, and tibial nerve. Locations were visualized by combining a multiplex retrograde tracking technique compatible with three-dimensional imaging of solvent-cleared organs (3DISCO) and 3-D imaging technology based on lightsheet fluorescence microscopy (LSFM). Additionally, we propose the hypothesis that “messenger zones” exist as interlaced areas between the motoneuron pools that dominate the synergistic or antagonist muscle groups. We hypothesize that these interlaced neurons may participate in muscle coordination as messenger neurons. Analysis revealed the precise mutual positional relationships among the many motoneurons that innervate different deep muscles of the mouse. Not only do these findings update and supplement our knowledge regarding the overall spatial layout of spinal motoneurons that control mouse limb muscles, but they also provide insights into the mechanisms through which muscle activity is coordinated and the architecture of motor circuits.
Fibroblast growth factor 21 inhibits ferroptosis following spinal cord injury by regulating heme oxygenase-1
Authors: Gu Qi , Sha Weiping , Huang Qun , Wang Jin , Zhu Yi , Xu Tianli , Xu Zhenhua , Zhu Qiancheng , Ge Jianfei , Tian Shoujin , Lin Xiaolong 
Published: November 2023

Abstract

JOURNAL/nrgr/04.03/01300535-202407000-00037/figure1/v/2023-11-20T171125Z/r/image-tiff

Interfering with the ferroptosis pathway is a new strategy for the treatment of spinal cord injury. Fibroblast growth factor 21 can inhibit ferroptosis and promote neurofunctional recovery, while heme oxygenase-1 is a regulator of iron and reactive oxygen species homeostasis. The relationship between heme oxygenase-1 and ferroptosis remains controversial. In this study, we used a spinal cord injury rat model to show that the levels of fibroblast growth factor 21 in spinal cord tissue decreased after spinal cord injury. In addition, there was a significant aggravation of ferroptosis and a rapid increase in heme oxygenase-1 expression after spinal cord injury. Further, heme oxygenase-1 aggravated ferroptosis after spinal cord injury, while fibroblast growth factor 21 inhibited ferroptosis by downregulating heme oxygenase-1. Thus, the activation of fibroblast growth factor 21 may provide a potential treatment for spinal cord injury. These findings could provide a new potential mechanistic explanation for fibroblast growth factor 21 in the treatment of spinal cord injury.
Comprehensive review on millets: Nutritional values, effect of food processing and dietary aspects
Authors: Maurya Rahul , Boini Thirupataiah , Misro Lakshminarayana , Radhakrishnan Thulasi , Sreedharan Aswani Pulikunnel , Gaidhani Dhanashree 
Published: November 2023

Millets are a group of small-seeded grains cultivated for centuries as staple food crops in many parts of the world. In the recent years, there has been a growing interest in millet due to its exceptional nutritional and health benefits. Millets are rich in essential nutrients such as proteins, dietary fiber, vitamins, minerals, and antioxidants. They are also gluten-free and have a low glycemic index, making them suitable for individuals with gluten intolerance or diabetes. Studies have shown that regular millet consumption can contribute to several health benefits. The high fiber content in millet aids digestion, prevents constipation, and promotes a healthy gut microbiome. Millets reduce the risk of chronic diseases, including cardiovascular diseases, type 2 diabetes, and certain cancers. The antioxidants in millet help to protect against oxidative stress and inflammation, which are underlying factors in various conditions.
Furthermore, millet has a positive impact on weight management. The combination of high fiber and low glycemic index in millets promotes satiety, regulates blood sugar levels, and helps to maintain a healthy body weight. Additionally, millet has anti-inflammatory, antimicrobial, and anticancer properties. In conclusion, millet offers a wide range of nutritional and health benefits. Their nutrient density, gluten-free nature, and low glycemic index make them valuable in a balanced diet. Incorporating millet into regular meals can contribute to improved overall health and well-being. Further research is needed to explore the full potential of millets and their specific health effects on different populations. This review discussed the various involved government bodies and their dietary guidelines. Policy development and dietary guidelines play a crucial role in promoting millet consumption.