bluuebunny/crossref_metadata_2025_split huggingface dataset:
Syntheses, Structures, Second‐Harmonic Generating, and Ferroelectric Properties of Tungsten Bronzes: A6M2M′8O30 (A: Sr2+, Ba2+, or Pb2+; M: Ti4+, Zr4+, or Hf4+; M′: Nb5+ or Ta5+).
Authors: Chi Eun Ok , Gandini Alberto , Ok Kang Min , Zhang Lei , Halasyamani P. Shiv 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
High‐Energy‐Density Materials: Synthesis and Characterization of N+5[P(N3)6]‐, N+5[B(N3)4]‐, N+5[HF2]‐×nHF, N+5[BF4]‐, N+5[PF6]‐, and N+5[SO3F]‐.
Authors: Haiges Ralf , Schneider Stefan , Schroer Thorsten , Christe Karl O. 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Lithium Acetate‐Catalyzed Aldol Reaction Between Aldehyde and Trimethylsilyl Enolate in Anhydrous or Water‐Containing N,N‐Dimethylformamide.
Authors: Nakagawa Takashi , Fujisawa Hidehiko , Nagata Yuzo , Mukaiyama Teruaki 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reaction of Aryl Di‐, Tri‐, or Tetrabromides with Arylboronic Acids or Alkenes in the Presence of a Palladium‐Tetraphosphine Catalyst.
Authors: Berthiol Florian , Kondolff Isabelle , Doucet Henri , Santelli Maurice 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stereoselective Synthesis of Functionalized Triol Units by SnCl4 Promoted Allylation of α‐Benzyloxyaldehydes: Crucial Role of the Stoichiometry of the Lewis Acid.
Authors: Dubost Christophe , Leroy Bernard , Marko Istvan E. , Tinant Bernard , Declercq Jean‐Paul , Bryans Justin 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Hemisynthesis of Methyl Pyrethroates from γ‐Alkoxy‐Alkylidene Malonates and Isopropylidenediphenylsulfurane and Isopropylidenetriphenylphosphorane.
Authors: Krief Alain , Froidbise Alexandre 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Reactions of Azomethines Containing a m‐Phenoxyphenyl Group. Part 2. Chemical Transformations of N‐Aryl‐m‐phenoxyphenylmethanimines and Arylhydrazones of m‐Phenoxybenzaldehyde.
Authors: Popov Yu. V. , Korchagina T. K. , Chicherina G. V. , Ermakova T. A. 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Identification of [(Naphthalene‐1‐carbonyl)‐amino]‐acetic Acid Derivatives as Nonnucleoside Inhibitors of HCV NS5B RNA Dependent RNA Polymerase.
Authors: Gopalsamy Ariamala , Lim Kitae , Ellingboe John W. , Krishnamurthy Girija , Orlowski Mark , Feld Boris , van Zeijl Marja , Howe Anita Y. M. 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
β‐Polynitration of 5,10,15,20‐tetrakis(2′,6′‐Dichlorophenyl)porphyrins with HNO3 and Cu(NO3)2 on Clay Using Microwave Irradiation.
Authors: Chauhan S. M. S. , Kumar Anil , Srinivas K. A. 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Six New 2‐Aryl‐N‐biphenyl Benzimidazoles and Crystal Structure of Methyl 4′‐[(2‐p‐Chlorophenyl‐1H‐benzimidazole‐1‐yl)‐methyl] biphenyl‐2‐carboxylate.
Authors: Zhiming Zhou , Weifa Yu , Jun Zhang , Xinqi Zhao , Congxuan Yu 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of New Coumarin 3‐(N‐Aryl) Sulfonamides and Their Anticancer Activity.
Authors: Srinivasa Reddy Natala , Mallireddigari Muralidhar Reddy , Cosenza Stephen , Gumireddy Kiranmai , Bell Stanley C. , Premkumar Reddy E. , Ramana Reddy M. V. 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Aryl‐Substituted Quinoline Derivatives via Broensted Acid‐Catalyzed [4 + 2] Aza Diels—Alder Reaction.
Authors: Akiyama Takahiko , Nakashima Saeko , Yokota Koji , Fuchibe Kohei 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
4,5‐Dihydro‐3H‐benzo[c]azepines from 1,7‐Electrocyclization Reactions of 2‐Aza‐4,5‐benzoheptatrienyllithium Compounds.
Authors: Gerdes Klaus , Sagar Pramod , Froehlich Roland , Wibbeling Birgit , Wuerthwein Ernst‐Ulrich 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis, Conformation and PKC Isozyme Surrogate Binding of Indolinelactam‐Vs, New Conformationally Restricted Analogues of (‐)‐Indolactam‐V.
Authors: Nakagawa Yu , Irie Kazuhiro , Komiya Yusuke , Ohigashi Hajime , Tsuda Ken‐ichiro 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Affordable Asymmetric Olefin Hydrogenation Using Monodentate Phosphoramidites
Authors: De Vries Andre H. M. , Boogers Jeroen A. F. , van den Berg Michel , Pena Diego , Minnaard Adriaan J. , Feringa Ben L. , de Vries Johannes G. 
Published: November 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Ionization‐Induced Proton Transfer in Model DNA Base Pairs: A Theoretical Study of the Radical Ions of the 7‐Azaindole Dimer
Authors: Chen Hsing‐Yin , Chao Ito 
Published: November 2004

AbstractProton‐transfer reactions of the radical anion and cation of the 7‐Azaindole (7AI) dimer were investigated by means of density functional theory (DFT). The calculated results for the dimer anion and cation were very similar. Three equilibrium structures, which correspond to the non‐proton‐transferred (normal), the single‐proton‐transferred (SPT) and the double‐proton‐transferred (tautomeric) forms, were found. The transition states for proton‐transfer reactions were also located. The calculations showed that the first proton‐transfer reaction (normal→SPT) is exothermic and almost barrier‐free; therefore, it should occur spontaneously in the period of a vibration. In contrast, the second proton‐transfer reaction (SPT→tautomer) was found to be far less‐probable in terms of reaction energy and barrier. Hence, it was concluded that both (7AI)2 and (7AI)2 exist in the SPT form. The conclusion was further confirmed by the calculated electron vertical detachment energy (VDE) of the SPT form of (7AI)2, 1.33 eV, which is very close to the experimental measurement of 1.35 eV. The calculated VDEs of the normal and tautomeric (7AI)2 forms were too small compared to the experimental value. The proton transfer process was found to be multidimensional in nature involving not only proton motion but also intermolecular rocking motion. In addition, IR spectra were calculated and reported. The spectra of the three structures showed very different features and, therefore, can be considered as fingerprints for future experimental identifications. The implications of these results to biology and spectroscopy are also briefly discussed.
Potentiometric Biosensors Based on ISFETs and Immobilized Cholinesterases
Authors: Dzyadevych Sergei V. , Arkhypova Valentyna N. , Martelet Claude , Jaffrezic‐Renault Nicole , Chovelon Jean‐Marc , El'skaya Anna V. , Soldatkin Alexey P. 
Published: November 2004

AbstractThis paper describes the authors' achievements in the development, investigation, and application of cholinesterase biosensors based on ISFETs. Various biosensors for determination of concentrations of different toxic substances (organophosphorous and carbamate pesticides, hypochlorite, glycoalkaloids) were designed on the basis of reversible and/or irreversible enzyme inhibition effects. The main analytical characteristics of the biosensors developed have been studied under different conditions and optimal experimental protocols for toxic substances determination have been proposed. Most of these biosensors show a high reproducibility and a good operational and storage stability. A quite good correlation with results obtained through routinely used standard methods as HPLC has been shown.
A New General Equation of the Polarographic Waves
Authors: Ruiz Morales Juan Carlos , Trujillo Jacinto del Castillo Juan José , Barrera Niebla Manuel , Placeres Jesús César Rodríguez 
Published: November 2004

AbstractA new general equation of the polarographic waves that improves the accuracy of the analysis has been obtained. The theoretical approach has been developed for Current Sampled DC Polarography or TAST Polarography, and can be used to study reversible, irreversible and quasi‐reversible waves. In order to facilitate the use of the new equation proposed, we have developed a computer program, TOP v1.0. This version works on Windows 32 bits systems (95/98/NT/Xp).
Spatial geochemical and isotopic characteristics associated with groundwater flow in the North China Plain
Authors: Chen Jianyao , Tang Changyuan , Sakura Yasuo , Kondoh Akihiko , Yu Jingjie , Shimada Jun , Tanaka Tadashi 
Published: November 2004

AbstractThe North China Plain (NCP) is an important agricultural area in China and has a high population density. Serious water shortages have occurred in this region over the last 20 years. Water transfer from the Yangtze River (the east route) was initiated in the year 2002 to provide water for the major cities of the NCP. This study was carried out before the implementation of the water transfer project, focusing on the spatial integration of the groundwater flow system and geochemical characteristics, which are mainly controlled by tectonics, geomorphology, and lithology. The field survey and the geochemical analyses of the groundwater samples indicated that the groundwater in the NCP has a two‐layer structure, with a boundary at a depth of about 100–150 m. The two layers differ in pH, concentrations of SiO2 and major ions, and isotopes (18O, deuterium and tritium (T)). Chemical components in the upper layer showed a wider range and higher variability than those in the lower layer, indicating the impact of human activity. The flow direction of the groundwater in the upper layer was examined in detail in two profiles, showing that the upper layer flows east towards the Cangzhou–Daming fault, while the groundwater in the lower layer flows northeast towards Tianjin. Three hydrogeological zones are identified: recharge (Zone I), intermediate (Zone II), and discharge (Zone III). The recharge zone was found to be low in chloride (Cl−) but high in T. The discharge zone was found to be high in Cl− and low in T. This may be due to the difference in groundwater age. The discharge zone was subdivided into two sub‐zones, Zone III1 and Zone III2, by considering the effects of human activities. Zone III2 was strongly affected by water diversions from the Yellow River. As groundwater flows from the recharge zone to the intermediate and discharge zones, chemical patterns evolve in the order: Ca‐HCO3 > Mg‐HCO3 > Na‐Cl + SO4. Copyright © 2004 John Wiley & Sons, Ltd.
Evidence of a dominant negative mutant of yeast methionine aminopeptidase type 2 in Saccharomyces cerevisiae
Authors: Vetro Joseph A. , Dummitt Benjamin , Micka William S. , Chang Yie‐Hwa 
Published: November 2004

AbstractEukaryotic methionine aminopeptidase type 2 (MetAP2, MetAP2 gene (MAP2)), together with eukaryotic MetAP1, cotranslationally hydrolyzes initiator methionine from nascent polypeptides when the side chain of the second residue is small and uncharged. In this report, we took advantage of the yeast (Saccharomyces cerevisiae) map1 null strain's reliance on MetAP2 activity for the growth and viability to provide evidence of the first dominant negative mutant of eukaryotic MetAP2. Replacement of the conserved His174 with alanine within the C‐terminal catalytic domain of yeast MetAP2 eliminated detectable catalytic activity against a peptide substrate in vitro. Overexpression of MetAP2 (H174A) under the strong GPD promoter in a yeast map1 null strain was lethal, whereas overexpression under the weaker GAL1 promoter slightly inhibited map1 null growth. Deletion mutants further revealed that the N‐terminal region of MetAP2 (residues 2–57) is essential but not sufficient for MetAP2 (H174A) to fully interfere with map1 null growth. Together, these results indicate that catalytically inactive MetAP2 is a dominant negative mutant that requires its N‐terminal region to interfere with wild‐type MetAP2 function. © 2004 Wiley‐Liss, Inc.
C3‐induced 3LL cell proliferation is mediated by C kinase
Authors: Longo Agostina , Gradini Roberto , Mattei Vincenzo , Morgante Emanuela , Sale Patrizio , Tafani Marco , Lipari Marcella , Pontieri Giuseppe M. , Russo Matteo A. 
Published: November 2004

AbstractIt has been demonstrated that the third component of complement (C3)1 and its peptides increase normal and tumour cell proliferation. However, the signal cascade responsible for this phenomenon is still unknown. In this study, we elucidate some of the mechanisms involved in the signalling of C3 stimulation of cell proliferation. We have first investigated the in and out traffic of C3 peptides, then we have identified the subcellular localisation of internalised C3 and, finally, we have explored the role of protein phosphorylation in C3 traffic and in the proliferation of the Lewis lung carcinoma (3LL) cells. Our results indicate that traffic of C3 is not dependent on cytoskeletal integrity and requires protein kinase C‐dependent phosphorylation. In addition, proliferation of 3LL cells stimulated by C3 depends on both C3 internalisation and protein‐kinase C phosphorylation. © 2004 Wiley‐Liss, Inc.
Role of Thy‐1 in in vivo and in vitro neural development and regeneration of dorsal root ganglionic neurons
Authors: Chen Chien‐Hsing , Wang Seu‐Mei , Yang Shih‐Hung , Jeng Chung‐Jiuan 
Published: November 2004

AbstractWe have examined the expression of Thy‐1, an abundant glycosylphosphatidylinositol (GPI)‐anchored glycoprotein, in dorsal root ganglia (DRG) and associated nerve fascicles, during postnatal development and following a nerve crush. The expression levels of Thy‐1 in DRG neurons, dorsal roots, and central processes in spinal cord were rather low at postnatal day 2, and gradually increased as DRG neurons matured. During early development, the expression of Thy‐1 within DRG neurons was low and equally distributed between plasma membrane and cytosol. With maturation, the staining intensities of Thy‐1 in both the plasma membrane and the cytosol of DRG neurons became increased. We also studied Thy‐1 expression in the regeneration of mature DRG neurons following the crush injury of sciatic nerve. Two days after the crush injury, Thy‐1 expression dramatically decreased in the DRG neurons on the lesion side. Between 4 and 7 days after the injury, the expression of Thy‐1 gradually increased and returned to a normal level 1 week after the sciatic nerve crush. The time course of the up‐regulation of Thy‐1 expression during regeneration matched that of the recovery of sensory functions, such as pain withdraw reflex, placing reflex, and the score of Basso–Beattie–Bresnahan Locomotor Rating Scale. Taken together, our results suggest that Thy‐1 expression is developmentally regulated and is closely associated with the functional maturation of DRG neurons during both postnatal development and nerve regeneration. Furthermore, perturbation of Thy‐1 function with anti‐Thy‐1 antibodies promoted neurite outgrowth from primary cultured DRG neurons, again confirming the inhibitory role of Thy‐1 on neurite outgrowth. © 2004 Wiley‐Liss, Inc.
Extensive theoretical studies on the low‐lying electronic states of indium monochloride cation, InCl+
Authors: Zou Wenli , Liu Wenjian 
Published: November 2004

AbstractThe global potential energy curves for the 14 low‐lying doublet and quartet Λ‐S states of InCl+ are calculated at the scalar relativistic MR‐CISD+Q (multireference configuration interaction with single and double excitations, and Davidson's correction) level of theory. Spin‐orbit coupling is accounted for via the state interaction approach with the full Breit–Pauli Hamiltonian, which leads to 30 Ω states. The computed spectroscopic constants of nine bound Λ‐S states and 17 bound Ω states are in good agreement with the available experimental data. The transition dipole moments and Franck–Condon factors of selected transitions are also calculated, from which the corresponding radiative lifetimes are derived. © 2004 Wiley Periodicals, Inc. J Comput Chem 26: 106–113, 2005
Junmei Wang, Romain M. Wolf, James W. Caldwell, Peter A. Kollman, and David A. Case, "Development and testing of a general amber force field"Journal of Computational Chemistry(2004) 25(9) 1157–1174
Authors: Wang Junmei , Wolf Romain M. , Caldwell James W. , Kollman Peter A. , Case David A. 
Published: November 2004

AbstractThe original article to which this Erratum refers was published in Journal of Computational Chemistry (2004) 25(9) 1157–1174
Charge distribution in the water molecule—A comparison of methods
Authors: Martin F. , Zipse H. 
Published: November 2004

AbstractThe charge distribution in the water molecule has been analyzed using a broad variety of basis sets, four different quantum mechanical methods (Hartree–Fock, Becke3LYP, MP2, and QCISD), and six population analysis methods (Mulliken, NPA, AIM, CHELPG, Merz–Kollman, and Resp). The influence of the molecular structure on the calculated atomic charges has been studied using small perturbations of the experimentally determined structure. © 2004 Wiley Periodicals, Inc. J Comput Chem 26: 97–105, 2005
Protein polymer build‐up during wheat grain development: influences of temperature and nitrogen timing
Authors: Johansson Eva , Kuktaite Ramune , Andersson Allan , Prieto‐Linde Maria Luisa 
Published: November 2004

AbstractThe amount and size distribution of polymeric protein, environmentally influenced by temperature and nitrogen timing, is an important factor determining gluten strength in wheat. Differences in mature wheat might be explained by alterations in accumulation and build‐up of proteins in the developing wheat grain. One cultivar was grown to maturity in a greenhouse using two temperatures and four nitrogen regimes. Plants were harvested during grain development and protein compositions were determined. Proteins were accumulated and built up similarly independent of temperature and nitrogen regime. Temperature influenced the protein concentration significantly, for all protein types throughout the grain development period and at maturity. The time for increase in amount of polymeric proteins differed with temperature if time was measured as days after anthesis, but not if time was measured as degree‐days. Different temperature regimes did not generally result in changes in amount and size distribution of polymeric protein. The combination of lower temperature, different nitrogen regimes and one of the cultivations led to changes in the amount and size distribution of polymeric protein in mature grains. These differences were due to a change in amount of SDS‐extractable polymeric and large monomeric proteins during grain development, indicating influences on disulphide bond formation. Copyright © 2004 Society of Chemical Industry
Consumer perceptions of novel fruit and familiar fruit: a repertory grid application
Authors: Jaeger Sara R , Rossiter Karen L , Lau Karen 
Published: November 2004

AbstractTo explore how consumers perceive novel and familiar fruit, repertory grid interviews were carried out with 60 New Zealand women. Participants described their perceptions of nine fruit varying in familiarity. The data analysis established a two‐dimensional stimuli space that separated samples with respect to familiarity and the amount of preparation required. Fruit that was familiar was characterised as being well liked, easily available in shops and by a number of different use situations. The primary association with novel fruit was that it was expensive. The participants could not readily think of use situations for fruit they were unfamiliar with. Consumers were separated into groups according to the trait of food neophobia, which pertains to an individual's stable propensity to approach or avoid novel foods. When comparing the most neophobic (n = 14; avoids novel foods) and most neophilic (n = 14; approaches novel foods), individuals perceptual differences were uncovered pertaining to which of the fruit were considered novel and to the suitability of some usage situations (cooking and for children). This finding contributed to the growing evidence of the relationship between food neophobia and consumers' everyday food‐related behaviour. Copyright © 2004 Society of Chemical Industry
Atypical protein kinase C‐ζ modulates clonogenicity, motility, and secretion of proteolytic enzymes in murine mammary cells
Authors: Urtreger Alejandro J. , Grossoni Valeria C. , Falbo Karina B. , Kazanietz Marcelo G. , Bal de Kier Joffé Elisa D. 
Published: November 2004

AbstractIn this paper, we investigated whether protein kinase C‐ζ (PKCζ), a member of the atypical PKC family, induces phenotypic alterations associated with malignant transformation and tumor progression in mammary cells. The stable overexpression of PKCζ in immortalized mammary epithelial cells (NMuMG), activates the mitogenic extracellular signal‐regulated kinase (ERK) pathway, enhanced clonal cell growth and exerts profound effects on proteases secretion. The effect on proteases expression seems to be specific for urokinase‐type plasminogen activator and metalloproteinase‐9 (MMP‐9) because no modulation in MMP‐2 and MMP‐3 production could be detected. In addition, our experiments demonstrated that PKCζ overexpression markedly altered the adhesive, spreading, and migratory abilities of NMuMG cells. The overexpression of this enzyme was not sufficient to confer an anchorage‐independent growth capacity. An extensive mutational analysis of PKCζ revealed that the effects observed in NMuMG cells were strictly dependent on the kinase (catalytic) domain of the enzyme. Taken together, these results suggest that in mammary cells PKCζ modulates several of the critical events involved in tumor development and dissemination through the activation of mitogen activated protein kinase (MAPK)/ERK pathway. © 2004 Wiley‐Liss, Inc.
Comparative study of macro‐ and microsurgical extrahepatic cholestasis in the rat
Authors: Aller Maria Angeles , Duran Manuel , Ortega Luis , Arias Jorge Luis , Nava Maria Paz , Prieto Isabel , Arias Jaime 
Published: November 2004

AbstractThe long‐term (5‐week) evolution of two experimental models of extrahepatic cholestasis, i.e., macrosurgical by bile duct ligation (n = 20) and microsurgical by biliary tract resection (n = 13), is studied. All cholestatic animals showed jaundice, choluria, and portosystemic collateral circulation. Macrosurgical cholestasis causes greater hepatosplenomegaly, hilar biliary pseudocysts, and ascites. Microsurgical extrahepatic cholestasis occurs with a lower degree of hepatosplenomegaly as well as with serum increase (P < 0.001) of γ‐GT and alkaline phosphatase. The bile ductular proliferation in the four hepatic lobes is very intense (P < 0.001) in both experimental models. The differences between both experimental models may be considered secondary to the increase of the predisposition to infection in rats with bile duct ligation, that complicates their evolution. The microsurgical cholestasis model could be useful in studying cholestasis secondary to biliary atresia. © 2004 Wiley‐Liss, Inc. Microsurgery 24:442–447, 2004.