bluuebunny/crossref_metadata_2025_split huggingface dataset:
SAGA1 and SAGA2 promote starch formation around proto-pyrenoids in Arabidopsis chloroplasts
Authors: Atkinson Nicky , Stringer Rhea , Mitchell Stephen R , Seung David , McCormick Alistair J. 
Published: November 2023

AbstractThe pyrenoid is a chloroplastic microcompartment in which most algae and some terrestrial plants condense the primary carboxylase, Rubisco (ribulose-1,5-bisphosphate carboxylase/oxygenase) as part of a CO2-concentrating mechanism that improves the efficiency of CO2capture. Engineering a pyrenoid-based CO2-concentrating mechanism (pCCM) into C3 crop plants is a promising strategy to enhance yield capacities and resilience to the changing climate. Many pyrenoids are characterized by a sheath of starch plates that is proposed to act as a barrier to limit CO2diffusion. Recently, we have reconstituted a phase-separated ‘proto-pyrenoid’ Rubisco matrix in the model C3 plantArabidopsis thalianausing proteins from the alga with the most well studied pyrenoid,Chlamydomonas reinhardtii(1). Here we describe the impact of introducing the Chlamydomonas proteins StArch Granules Abnormal 1 (SAGA1) and SAGA2, which are associated with the regulation of pyrenoid starch biogenesis and morphology. We show that SAGA1 localizes to the proto-pyrenoid in engineered Arabidopsis plants, which results in the formation of atypical spherical starch granules enclosed within the proto-pyrenoid condensate and adjacent plate-like granules that partially cover the condensate, but without modifying the total amount of chloroplastic starch accrued. Additional expression of SAGA2 further increases the proportion of starch synthesised as adjacent plate-like granules that fully encircle the proto-pyrenoid. Our findings pave the way to assembling a diffusion barrier as part of a functional pCCM in vascular plants, whilst also advancing our understanding of the roles of SAGA1 and SAGA2 in starch sheath formation and opening novel avenues for engineering starch morphology.
Bait, not reward: CO2-enrichedNepenthespitchers secrete toxic nectar
Authors: Lathika Chandni Chandran , Sujatha Gokul Baburaj , Thomas Gintu , Johnson Anil John , Viswanathan Gayathri , Varghese Thania Sara , Mohamed Saleem , Shereefa Lubaina Abdulhadeef , Baby Sabulal 
Published: November 2023

AbstractNepenthespitchers are leaf-evolved biological traps holding high levels of CO2within them. Extrafloral nectar (EFN) secreted by these pitchers has long been regarded as the major reward to visiting arthropods, but its chemical constituents and their role in prey capture are least explored. Here we demonstrateNepenthesEFN as a sugar (glucose-fructose-sucrose) mix with high C:N ratio, minimal amino acids, proteins, and vitamin C.Nepenthes khasianaperistome and lid EFNs displayed strong acetylcholinesterase (AChE) inhibition; the naphthoquinone derivative, (+)-isoshinanolone, has been identified as the AChE inhibitor. Plumbagin, the major volatile naphthoquinone inNepenthes, also showed strong AChE inhibition. Direct EFN– and (+)-isoshinanolone-feeding bioassays demonstrated symptoms of cholinergic toxicity in ants. We testify thatNepenthesEFN is a toxic bait which hinders neuronal activity in visiting arthropods. These unique traps adopt various deceptive strategies for prey capture, and our discovery abolishes the notion thatNepenthesEFN is a reward to visiting ants and other arthropods. Moreover, our findings infer elevated CO2within their pitchers as the key factor influencing the growth, metabolism, herbivory, and carnivory inNepenthes.HighlightNepenthesextrafloral nectar has high content of carbohydrates and minimal nitrogenous metabolites. It is laced with (+)-isoshinanolone, an acetylcholinesterase inhibitor, and acts as a toxic bait, aiding prey capture.
Correlation Between Neighborhood Built Environment and Leisure Walking Time Around a Riverside Park
Authors: Gong Youngeun , Kim Eun Jung 
Published: November 2023

Objectives: This study aimed to investigate whether the distance to a riverside park and the neighborhood built environment are related to individuals’ leisure walking time by examining the case of the Geumho riverside park in Daegu, South Korea. Background: Walking, being an inexpensive means of transportation with numerous health benefits, is influenced by the conditions of neighborhood built environments. Methods: A survey was conducted from October 12 to November 8, 2022, including 184 adults aged 18 years or older. The dependent variable was the total weekly minutes of leisure walking, and the independent variables included the neighborhood built environment measured objectively using geographic information systems as well as demographic/individual characteristics and health attitude data. Analysis of variance was conducted to determine whether leisure walking time differed depending on the distance to the riverside park, and regression analysis was conducted to examine the association between leisure walking time and the neighborhood built environment. Results: Individuals living within a quarter-mile of the park walked an average of 155 min per week for leisure, which was significantly more than those living further than 1 mile (mean = 85.14 min/week). Moreover, greater access to the park, higher crosswalk density, and a lower road density were associated with more leisure walking time for residents. Conclusions: The findings of this study indicate that good access to riverside parks and pedestrian-centered neighborhood environments may be related to leisure walking among residents. These findings hold significance for urban planning and the formulation of public health policies.
Treatment of sheep prior to movement: its contribution to an effective scab (psoroptic mange) management strategy
Authors: Lihou Katie , Wall Richard , Nixon Emily 
Published: November 2023

Abstract
Background
Ovine psoroptic mange (sheep scab) is an important disease of sheep worldwide caused by the parasitic mite, Psoroptes ovis. It has a negative impact on animal welfare and leads to significant economic losses for the sheep industry. Effective and targeted management is required to limit its transmission.

Methods
A stochastic metapopulation model of sheep scab transmission is used to investigate the contribution of the treatment of sheep prior to movements to sales, gatherings (predominantly markets) and away grazing to the reduction of prevalence of farms with scab in Great Britain.

Results
Treatment prior to movement to gatherings resulted in an 86% reduction in the overall prevalence of farms with scab and was more effective at reducing the overall prevalence of farms with scab than treatment before other categories of movements. The relative risk of farms having scab infection was inversely related to the percentage of farms which treated, but this relationship was not linear, with the biggest declines in the prevalence of farms with scab being achieved by small percentages of farms treating; a 50% relative reduction in the farm prevalence was achieved with only 15% of farms treating prior to gathering movements.

Conclusions
The results suggest that pre-movement treatment of sheep could make an important contribution to national scab control and, in practice, the approach could be more highly targeted if used in conjunction with known geographic and management risk factors for scab.

Graphical Abstract
Higher plasma aldosterone concentrations in patients with aortic diseases and hypertension: a retrospective observational study
Authors: Pu Yuting , Yang Guifang , Pan Xiaogao , Zhou Yang , Zhong Aifang , Ding Ning , Su Yingjie , Peng Wen , Zeng Mengping , Guo Tuo , Chai Xiangping 
Published: November 2023

Abstract
Background
Aortic diseases remain a highly perilous macrovascular condition. The relationship between circulating aldosterone and aortic diseases is rarely explored, thus we investigated the difference in plasma aldosterone concentration (PAC) between patients with and without aortic disease in hypertensive people.

Methods
We analyzed 926 patients with hypertension, ranging in age from 18 to 89 years, who had their PAC measured from the hospital's electronic database. The case group and control group were defined based on inclusion and exclusion criteria. The analysis included general information, clinical data, biochemical data, and medical imaging examination results as covariates. To further evaluate the difference in PAC between primary hypertension patients with aortic disease and those without, we used multivariate logistic regression analysis and also employed propensity score matching to minimize the influence of confounding factors.

Results
In total, 394 participants were included in the analysis, with 66 individuals diagnosed with aortic diseases and 328 in the control group. The participants were predominantly male (64.5%) and over the age of 50 (68.5%), with an average PAC of 19.95 ng/dL. After controlling for confounding factors, the results showed hypertension patients with aortic disease were more likely to have high PAC levels than those without aortic disease (OR = 1.138, 95% CI [1.062 to 1.238]). Subgroup analysis revealed consistent relationship between PAC and primary hypertensive patients with aortic disease across the different stratification variables. Additionally, hypertensive patients with aortic disease still have a risk of higher PAC levels than those without aortic disease, even after propensity score matching.

Conclusions
The results of this study suggest that primary hypertensive patients with aortic diseases have elevated levels of PAC, but the causal relationship between PAC and aortic disease requires further study.
Generation "Z's Perception of Religious Moderation and Tendency to Choose Religious Studies in Indonesia
Authors: Abdul Hopid  , Sama alee Abdunrorma , Nur Anisyah Rachmaningtyas  , Hanif Cahyo Adi Kistoro  
Published: November 2023

Purpose – The purpose of this research is to reveal the potential interest tendency of Gen Z in choosing the theme of religious studies, when Gen Z has an open character but does not want to be bound by a religious system that is too strict based on student experience.
Design/methods/approach – This type of research is qualitative research with a phenomenological approach. The focus of this phenomenological research is the researcher's curiosity about students' experiences in behavior and the extent of their perceptions related to the selection of religious studies in successive time series that occur to respondents. Respondents in this study consisted of 40 students from different schools. The respondents were selected by purposive sampling. The data analysis used is based on Bogdan and Biklen's method.
Findings – The experience of students in participating in the study tends to lead to themes that are easy to enjoy such as the theme of fiqh and akhlaq. This diversity shows the openness and openness of this shows the potential for more moderation in religious views and attitudes.
Research implications/limitations – Opening up knowledge is related to awareness of the importance of choosing religious studies, especially for the younger generation or known as Gen Z. Therefore, it is important to help teenagers to choose places for religious studies that do not lead to radicalism to the point of destroying proper understanding. Apart from that, the first step to start is through school. Schools should be more responsive and increase their sensitivity regarding student potential.
Originality/value – This research still has limitations, especially in collecting the number of respondents. Hopefully future researchers can minimize this deficiency, and subsequent research can be more perfect. Apart from that, future researchers can also measure the extent of religious literacy in students so that the studies that can be given can be measured well.
Healthcare Logistics System Planning for Facility Location of Aging Society
Authors: Amchang Chompoonut , Suraraksa Juthathip 
Published: November 2023

Healthcare facility location management is essential to the public infrastructure, particularly as it relates to access to the healthcare system. Therefore, the locations of primary healthcare centers (PHCs) must be sufficient to accommodate the size of the elderly population in the future. Thailand is entering an aging society. Most of research studied to improve service quality of healthcare more than consider amount of location of PHCs. So, the purpose of this study was to applied a geographic information system (GIS) to study coverage area of accessing to health facility location under condition of increasing elderly population. It analyzed by using the Dijkstra Algorithm and concept of last mile delivery center. For the elderly population, this research applied auto regression to forecast elderly population. The study found the population of elderly people will increase in every district by 2025, with the highest increase being in Khlong Sam Wa. The original locations point of PHCs in Bangkok included 145 locations, which can accommodate an area for the elderly to access a PHC. Health services need to be easily accessible by walking in 5-15 minutes [1]. Thus, the problem is the current locations of PHCs are insufficient to support a future aging society. This research applied the location of Covid-19 vaccine distribution model (CVDM) to support the positioning of healthcare services. The CVDM comprised 191 pharmacies/clinics then analysis the service coverage area. The point of location CVDM and PHCs which showed health services coverage by comparing walking times. This modal can increase service covering of walking in 5 minutes, 10 minutes, and 15 minutes of 4.34%, 11.78% and 20.35%, respectively. The efficiency of service cover-age for primary and secondary medical care for elder can be improved if the location of health service centers is increased.
Effects of Nursing Guidance About Venipuncture Versus Ordinary Syringe, A Comparative Study On Rates of Phlebotomy Hematoma
Authors: Hassan Anaam Mohammed , Mohammed Ghada Thabet , Hefnawy Gehan Refat , Khalil Shaymaa Sayed 
Published: November 2023

Objective: To assess the effects of nursing guidance about Venipuncture versus ordinary syringe, a Comparative Study on Rates of phlebotomy hematoma. Background: In order to reducing the incidence of phlebotomy hematoma, nurses should receive comprehensive training regarding appropriate blood sampling Study design and methods: Pre-posttest, comparative study design using a quasi-experimental design for both groups. Setting: The surgery departments at Assiut University Hospital. Subjects: There were 40 nurses in total coverage, and 100 randomly selected patients underwent blood sample. The nurses and patients were split into two equal groups. Tools: (I): Patients' assessment (personnel and clinical data), (II): Easy hematoma degree classification and (III) Nurses' awareness questionnaire (demographic characteristics, knowledge, and observation checklist). Results: A statistically significant difference the venipuncture and ordinary syringe groups regarding the rates of phlebotomy hematoma (wound quality of life and wound healing) with a significant correlation between them. Moreover, a statistically significant difference between nurses' knowledge and practice of applying the nursing guidance pre- and post-test. Conclusion: The nursing guidance had a beneficial impact on nurses' knowledge and practice, and it improved the rates of phlebotomy hematoma occurrence among patients who underwent venipuncture compared to the other group using an ordinary syringe Implications for research, policy, and practice: Enhance nurses' knowledge and practice, offer ongoing education and in-service training program to the surgery departments. Apply venipuncture to blood sampling to reduce the risk of phlebotomy hematomas.
Calculation of Structures Lying On an Anisotropic Basis
Authors: N Dyussembayev I. , Z Nigmetov M. , K Suimenova M. , I Izbassar A. , A Dyussembayev 
Published: November 2023

The definition of the nucleus and the influence function of a transversally isotropic half-space is considered. Expressions of deflection and internal forces in an infinite base plate are obtained, taking into account their deepening into the rock mass, as well as the effect of the anisotropy of the base on the distribution of deflections and internal forces. The results obtained serve as a reference for the reconciliation of the results obtained by numerical and computer methods. This calculation algorithm allows us to estimate the bearing capacity of an anisotropic soil base.
Pneumatic press machine Rice bran oil Extractor for a Pilot scale and its potential for the SME Scale: Performance of Yield and Anthocyanin Content
Authors: Nugrahani Ratri Ariatmi , Hendrawati Tri Yuni , Hasyim Ummul Habibah , Sari Fatma , Saputra Muhammad Ilham , Busratama Afryan , Ramadhani Annisyah 
Published: November 2023

: Rice is a food crop that serves as a source of energy. As an edible food, the rice skin is separated, which produces solid waste in the form of rice bran. Generally, the rice bran produced from the rice milling process is 8-12%. Rice bran is only used for animal feed. Rice bran contains various vitamins and antioxidants, one of which is anthocyanins. The benefits of anthocyanins include natural pH indicators, natural dyes usually used in food and beverages, and anticancer. Extraction in this study using a pneumatic press machine for pilot scale and the other aim of this research were study the potential of SME (small and medium enterprises) Scale. The analysis of rice bran oil is conducted by the Spectrophotometric method. The variables used in the extraction process in this study were pressures of 3, 4, 5, 6, and 7 bars and stabilization time of 8, 11, 14, 17 and 20 minutes with a pressure of 7 bar on the yield and the content of anthocyanins. The obtained yield is at the 7 bar, which was 6.45%. The yield shows that the pressure is related to the yield of rice bran oil. It shows that the highest anthocyanin content was obtained at the optimum stabilization time is 20 minutes with an anthocyanin content of 36.9 mg/kg. The capacity of this press machine is 5 kg, so by using the ratio of rice bran: solvent (1: 7), if the maximum raw material that can be processed is 625 gr and 4375 gr solvent, a yield of 40.3125 gr will be obtained. This value shows the potential for using a pneumatic press machine as a pilot scale extractor for SME (Small Medium Entreprise) needs
Starość jednak chorobą? Kontrowersje wokół nowej Międzynarodowej Statystycznej Klasyfikacji Chorób i Problemów Zdrowotnych ICD-11
Authors: Wieczorkowksa Magdalena 
Published: November 2023

Podczas prac nad nową rewizją Międzynarodowej Statystycznej Klasyfikacji Chorób i Problemów Zdrowotnych ICD-11 zaproponowano, by biologiczne starzenie się uznać za chorobę. Wprawdzie w literaturze przedmiotu pisano o biomedykalizacji starości i starzenia się (m.in. Estes i Binney), jednak decyzja o zrównaniu procesu biologicznego starzenia się ze stanem choroby i oficjalne jej legitymizowanie w ramach klasyfikacji ICD wydaje się mieć poważne konsekwencje dla postrzegania schyłkowej fazy ludzkiego życia. Propozycja ostatecznego umedycznienia starości i starzenia się znalazła zwolenników i przeciwników. Celem artykułu jest analiza dyskusji toczącej się na łamach czasopism naukowych i w przestrzeni medialnej w oparciu o rekonstrukcję stanowisk oraz argumenty używane przez zwolenników, jak i przeciwników biomedykalizacji starości. Zwolennicy medykalizacji starości wskazywali na realne korzyści płynące z uznania biologicznego starzenia się za chorobę (efektywna dystrybucja leków nakierowanych na tę „chorobę”, ubezpieczenia pozwalające na pokrycie kosztów jej leczenia). Krytycy tego podejścia podkreślali ageistyczne nastawienie jego propagatorów i wskazywali na takie konsekwencje jak dalsze wykluczenie osób starszych z życia społecznego i usług zdrowotnych, a także nierówności zdrowotnych w starzejących się społeczeństwach. Realizacja powyższego celu pozwoli także na wskazanie wielowymiarowych konsekwencji medykalizacji biologicznego starzenia się.
Życie i praca za granicą w zdrowiu i w chorobie
Authors: Pawlak-Kałuzińska Agnieszka 
Published: November 2023

Artykuł stanowi prezentację wstępnych, częściowych wyników badań przeprowadzanych w ramach projektu badawczego pt. (Nie)zdrowi migranci zarobkowi – osamotnienie, stres i choroba podczas emigracji zarobkowej oraz podejmowane strategie zaradcze realizowanego od sierpnia 2022 roku. Jednym z celów badania jest poznanie opinii migrantów i migrantek na temat stanu ich zdrowia przed emigracją oraz w trakcie trwania emigracji, a także strategii podejmowanych w celu utrzymania zdrowia i strategii podejmowanych w przypadku wystąpienia choroby. Obecnie próba liczy 150 osób, z których więcej niż połowa przebywa na emigracji od ponad 10 lat. Do oceny stanu zdrowia migrantów wykorzystano zarówno wskaźniki subiektywne, jak i deklaracje dotyczące obiektywnych wskaźników zdrowia. Badani migranci w momencie udania się na emigrację w większości cieszyli się bardzo dobrym lub dobrym stanem zdrowia, a więc w badanej próbie wystąpił efekt zdrowego migranta. Obecnie stan ich zdrowia ulega stopniowemu pogarszaniu się. Badani zgłaszają liczne dolegliwości zdrowotne, jednak tylko co piąty z nich cierpi na chorobę przewlekłą. Respondenci zazwyczaj wysoko oceniają służbę zdrowia w kraju emigracji i – jeśli zajdzie taka potrzeba – korzystają z niej częściej niż ze służby zdrowia w Polsce. Stosują jednak przede wszystkim strategie dbałości o zdrowie i samoleczenia. Istotną zmienną różnicującą otrzymane wyniki jest płeć badanych.
Second hand w przemianie. Transformacja ideowo– motywacyjnego kontekstu sklepów z używaną odzieżą
Authors: Uklańska Katarzyna 
Published: November 2023

Artykuł jest ujęciem zmiany znaczenia sklepów second hand w polskich warunkach w XXI w. Jego celem jest ukazanie przemiany ciucholandów w obrębie trzech płaszczyzn: idei towarzyszących tym sklepom, motywacji ich klientów oraz tożsamości, co wyraża nowe ich nazewnictwo, miejsce w przestrzeni publicznej oraz nowe zjawiska promujące drugi obieg ubrań. Analiza oparta jest na literaturze przedmiotu w badanym zakresie oraz zastanym dorobku empirycznym polskim i zagranicznym. Pozwoliła ona na sformułowanie wniosków o tym, że ciucholandy stanowią narzędzie idei zrównoważonej konsumpcji, co powoli dostrzegalne jest w motywacjach klientów tych sklepów. Także nazewnictwo, obecność w przestrzeni miejskiej i sposoby promocji nobilitują te sklepy, czyniąc z nich istotny element zrównoważonej konsumpcji.
Sens w pracy. Dlaczego ma znaczenie dla organizacji i o czym może świadczyć niezdolność do jego podtrzymania?
Authors: Kutyło Łukasz , Kubala Konrad 
Published: November 2023

Przedmiotem uwagi w artykule uczyniliśmy poczucie sensu z wykonywanej pracy. Nie kwestionując wniosków wyłaniających się z badań psychologicznych, postanowiliśmy spojrzeć na nie z innej perspektywy i wskazać, dlaczego poczucie to jest tak ważne dla sprawnego funkcjonowania organizacji. To od niego wydaje się bowiem zależeć zaangażowanie zawodowe pracowników, a jego brak niesie ze sobą wzrost kosztów, które trzeba przeznaczyć na monitorowanie ich pracy (w skrajnych przypadkach prowadzi zaś do anomii organizacyjnej). Chcieliśmy także pokazać, że niezdolność niektórych organizacji do podtrzymywania czy kształtowania sensu może być przejawem bardziej złożonego problemu, świadczącego o istnieniu nieefektywnej kultury organizacyjnej (np. spowalniającej rozwój gospodarczy). Założenia te spróbowaliśmy udowodnić, korzystając z danych dotyczących 21 krajów europejskich, pochodzących z badania pt. Work Orientations, zrealizowanego w 2015 roku w ramach Generalnego Sondażu Społecznego.