bluuebunny/crossref_metadata_2025_split huggingface dataset:
A comparison between erythrocytapheresis and venesection for the treatment of JAK2‐mutated polycythaemia
Authors: Ngo Trung Q. , Scott Matthew W. , Sirdesai Shreerang , Hempton Jennifer L. , Hodges Georgina S. , Campbell Philip J. 
Published: December 2023

AbstractBackgroundJAK2‐mutated polycythaemia vera (PV) is associated with reduced survival because of thrombotic events and haematological disease transformation. Therapeutic venesection has traditionally been used to lower haematocrit, but the technique of erythrocytapheresis has emerged over the last decade.AimTo compare erythrocytapheresis with venesection as treatment for PV by assessing medical efficacy and financial viability.MethodsOne hundred sixteen patients with PV who received red cell depletion therapy at Barwon Health between 2014 and 2021 were identified. The haematocrit drop after each session, interval between treatment times and number of sessions required to achieve a haematocrit <0.45 were compared with an independent t test. Thrombosis rates were compared with Pearson's chi‐squared test. Cost‐funding analysis was done by assessing the Weighted Inlier Equivalent Separation and National Weighted Activity Unit funding models.ResultsPatients treated with erythrocytapheresis achieved a greater haematocrit drop each treatment session (0.075 vs 0.03, P < 0.01), required fewer sessions to achieve a haematocrit <0.45 (1 vs 4, P < 0.01) and experienced fewer thrombotic complications (8.7% vs 32.1%, P = 0.02) than those treated with venesection. Cost‐funding analysis demonstrated that erythrocytapheresis was more financially viable with a surplus of AU$297 per session compared to a deficit of AU$176 with venesection. Even if funding for venesection is increased, the cost of erythrocytapheresis may be mitigated by a lower number of procedures required per year (3.8 vs 5.3, P < 0.01).ConclusionsErythrocytapheresis is more efficacious than venesection for the treatment of PV and is accompanied by rapid reductions in haematocrit and reduced thrombotic complications.
The effect of Li/Ce co‐doping on structural and electrical properties of Sr2−x(Li, Ce)x/2Nb2O7 piezoelectric ceramics
Authors: Yang Xinji , Chen Ning , Wang Fei , Tang Manjing , Xing Jie , Zhu Jianguo 
Published: December 2023

AbstractAs a typical perovskite‐like layered structure (PLS) ceramic, Sr2Nb2O7 (SNO) possesses a high Curie temperature TC value above 1300°C, which is expected to work in higher temperature environment. However, pure SNO presents a piezoelectric constant d33 value of ∼ 1 pC/N. Hence, (Li, Ce) ions are doped in SNO ceramics, which increases the distortion of oxygen octahedrons and enhances the intrinsic contribution of piezoelectric properties. The increased domain size with large proportion of high response areas means that the extrinsic contribution is also improved. The introduction of (Li, Ce) ions can also promote ceramic's grain growth and reduce oxygen vacancies, leading to the improvement of electrical properties. The optimal component Sr1.96(Li, Ce)0.02Nb2O7 ceramics exhibit a d33 value of 3.1 pC/N, a higher resistivity of 1.65×106
Ω·cm at 700°C and an excellent thermal stability (a d33 value of 3.0 pC/N after annealing at 1200°C for 2 h). This work provides an effective approach with simple process and low cost for the application of PLS materials in high‐temperature environments.
Cultures of power and politics: Two cases of the limits of anti‐essentialism in the political anthropology of lowland South America
Authors: Tym Christian , Saturno Silvana 
Published: December 2023

AbstractPost‐structuralism's focus on hegemonic power, subjection, and political opportunity remains pre‐eminent in political anthropology, but its appropriateness for the post‐neoliberal conjuncture is up for question. While the arrival of neoliberal multiculturalism brought contingent identities and strategic deployment of culture‐as‐product into focus, questions remain about how and why some groups mobilize to claim cultural rights while others decline to do so. For this reason, this article returns to an earlier concern in Latin American political anthropology with cultural differences in the conceptualization and execution of political organization and power. This argument is based on two ethnographic case studies—from the Venezuelan Pume and the Ecuadorian Shuar—that demonstrate the contemporary significance for indigenous politics of evolving autochthonous notions of power and their expression in conventional forms of social organization. These politico‐cultural qualities are already constituting the form and objectives of indigenous political action prior to their expression in the public fora whose terms and opportunities are often presented as driving indigenous people's politics. Such an approach is important for understanding the dilemmas of solidarity as indigenous groups become more empowered and diverse in their political orientations.
Risk factors for food contamination among children discharged from community management of acute malnutrition programmes in South Sudan: A cross‐sectional study and hazard analysis critical control point approach
Authors: Wells Joseph , Abugo David Gama , Angong John , Lamwaka Nancy Grace , Gallandat Karin , Hassan Jackson Lwate , Deng Lino , Save Dimple , Braun Laura , Gose Mesfin , Amanya Jacob , Ayoub Khamisa , King Sarah , Stobaugh Heather , Cumming Oliver , D'Mello‐Guyett Lauren 
Published: December 2023

AbstractChildren under‐5 years of age are particularly vulnerable to severe acute malnutrition (SAM), and the risk factors associated with relapse to SAM are poorly understood. Possible causes are asymptomatic or symptomatic infection with enteric pathogens, with contaminated food as a critical transmission route. This cross‐sectional study comprised a household survey with samples of child food (n = 382) and structured observations of food preparation (n = 197) among children aged 6–59 months that were discharged from treatment in community management of acute malnutrition (CMAM) programmes in South Sudan. We quantified Escherichia coli and total coliforms (TCs), measured in colony forming units per g of food (CFU/g), as indicators of microbial contamination of child food. A modified hazard analysis critical control point (HACCP) approach was utilised to determine critical control points (CCPs) followed by multivariate logistic regression analysis to understand the risk factors associated with contamination. Over 40% (n = 164) of samples were contaminated with E. coli (43% >0 E. coli CFU/g, 95% CI 38%–48%), and 90% (n = 343) had >10 TCs (CFU/g) (>10 TC CFU/g, 95% CI 87%–93%). Risk factors associated (p < 0.05) with child food contamination included if the child fed themselves (9.05 RR, 95% CI [3.18, 31.16]) and exposure to animals (2.63 RR, 95% CI [1.33, 5.34]). This study highlights the risk factors and potential control strategies that can support interventions that reduce food contamination exposure in young children and help further protect those that are highly vulnerable to recurrent exposure to enteric pathogens.
Current Trends in the Synthesis of Inorganic and Organoelement Phosphorus- and Sulfur-Containing Polymers. A Review
Authors: Tarasova N. P. , Krivoborodov E. G. , Mezhuev Ya. O. 
Published: December 2023

Abstract
An analysis of literature data on the set of reactions for the production of macromolecules with a high content of phosphorus and sulfur has been carried out, and basic approaches that allow the introduction of these elements into the composition of polymers and polymeric materials have been considered in compliance with the fundamental principles of green chemistry. Methods for synthesis of functional polymers under mild conditions that require minimal energy input from external sources, which can become new growth points for green industrial technologies, are considered. Particular attention focuses on the synthesis of polyphosphazenes and polyphosphoesters for biomedical purposes, as well as on the inverse vulcanization reaction to give polymers used in sorption wastewater treatment, the creation of current sources, and IR optics.
Peripheral nerve stimulation for saphenous neuralgia
Authors: McCullough Meghan , Kenney Deborah , Curtin Catherine , Ottestad Einar 
Published: December 2023

BackgroundInjury to saphenous nerve branches is frequent during knee surgery and can result in chronic pain. This saphenous neuralgia remains challenging to treat. Peripheral nerve stimulation (PNS) is a new potential non-pharmacologic treatment option. We present our outcomes experience using this technology in 12 patients.MethodsWe retrospectively reviewed PNS placement for saphenous neuralgia between 2000 and 2022 at a single institution. Demographic information was collected as well as response to the device. Four-question short-form Patient-Reported Outcome Measurement Information System (PROMIS) Scores were collected before and 2 weeks, 6 weeks, and 6 months postprocedure. Specific scores included pain interference and behavior, functional mobility, depression, anxiety, and sleep impairment. Change in pain interference measured by the short-form PROMIS tool at 6 months was chosen as the primary outcome.ResultsTwelve patients met inclusion criteria, with 10 patients having the full 6-month follow-up. In these 10 patients, the mean change from baseline in the short-form adjusted pain interference score (greater difference means improved pain) at 6 months was 5.8 (SD 6.5). Among all patients, average follow-up was 11.5 months (range 3–35 months). Most patients’ symptoms developed after knee surgery (84%). Prior to PNS, patients underwent other treatments including cryoablation (8%), radiofrequency ablation (16%), saphenous neurectomy (16%), or surgical release of adjacent nerves (25%). Ten patients (83%) reported any improvement in symptoms while two reported no benefit. Complications occurred in four patients (33%). Two patients had the device removed and a third discontinued use. PROMIS Scores for pain, functional mobility, mood, and sleep impairment all improved.DiscussionLimited effective treatments exist for saphenous neuralgia. Our case series demonstrates the potential of PNS as a treatment for saphenous neuralgia. Comparative effectiveness studies are warranted to assess whether our effect size is clinically relevant.
Reanimating experimental psychology: Media archaeology, Hugo Münsterberg, and the ‘Testing the Mind’ film series
Authors: Blatter Jeremy 
Published: December 2023

For historians of psychology, Hugo Münsterberg is best remembered as William James’ successor as director of the Harvard Psychological Laboratory and a pioneer of applied psychology. By contrast, for film and media studies scholars, Münsterberg is recognized less for his contributions to experimental psychology than for those to film theory, a field in which his penultimate book, The Photoplay: A Psychological Study (1916), is frequently claimed as an inaugural text. However, lost in the blind spots of both disciplinary perspectives has been a thorough examination of Münsterberg's collaboration with Paramount Pictures, translating psychological tests into experimental short films. Despite reaching millions of moviegoers in 1916, Münsterberg’s ‘Testing the Mind’ series has received little attention from historians of science and early cinema alike. One reason for this neglect is that, to date, not a single extant copy of a ‘Testing the Mind’ release has been located. This article is about the author's efforts, in collaboration with students, to reanimate these lost psychological tests for the screen through meticulous historical reconstruction based on the original scripts, journalistic accounts, and correspondence between Münsterberg and Paramount. This reconstructive process, I show, yields new insights into the relationship between psychology and early cinema and an opportunity for reflection on this promising new space for research at the intersection of media archaeology, the history of psychology, and experimental history of science. Film URL: https://archive.org/details/munsterberg_paramount.pictographs
Hepatocellular carcinoma in cirrhotic versus non-cirrhotic liver: Treatment and survival differences in a nationwide cohort
Authors: Engstrand Jennie , Stål Per , Gilg Stefan , Jansson Anders , Strömberg Cecilia 
Published: December 2023

Background and aims: Numerous studies have reported superior outcome for patients with hepatocellular carcinoma (HCC) in non-cirrhotic compared to cirrhotic livers. This cohort study aims to describe the clinical presentation, disease course, treatment approaches, and survival differences in a population-based setting. Methods: Data on patients diagnosed with HCC in Sweden between 2008 and 2018 were identified and extracted from the Swedish Liver registry (SweLiv). Descriptive and survival statistics were applied. Results: Among the 4259 identified patients, 34% had HCC in a non-cirrhotic liver. Cirrhotic patients presented at a younger age (median = 64 vs 74 years, p < 0.001) and with a poorer performance status (Eastern Cooperative Oncology Group (ECOG) = 0–1: 64% vs 69%, p = 0.024). Underlying liver disease was more prevalent among cirrhotic patients (81% vs 19%, p < 0.001). Tumors in non-cirrhotic livers were diagnosed at a more advanced stage (T3–T4: 46% vs 31%) and more frequently with metastatic disease at diagnosis (22% vs 10%, p < 0.001). Tumors were significantly larger in non-cirrhotic livers (median size of largest tumor 7.5 cm) compared to cirrhotic livers (3.5 cm) (p < 0.001). Curative interventions were more commonly intended (45% vs 37%, p < 0.001) and performed (40% vs 31%, p < 0.001) in the cirrhotic vs non-cirrhotic patients. Median survival was 19 months (95% confidence interval (CI) = 18–21 months), in patients with cirrhosis as compared to 13 months in non-cirrhotic patients (95% CI = 11–15) (p < 0.001). In the multivariable Cox regression model, cirrhosis was not an independent predictor of survival, neither among curatively nor palliatively treated patients. Conclusion: These population-based data show that patients with HCC in a cirrhotic liver receive curative treatment to a greater extent and benefit from superior survival compared to those with HCC in a non-cirrhotic liver. The differences in survival are more attributable to patient and tumor characteristics rather than the cirrhotic status itself. Clinical trial registration: not applicable. Patient confidentially: not applicable.
The effects of context and characteristics of women entrepreneurs on innovation performance
Authors: Chávez-Rivera María Eulalia , Ruíz-Jiménez Jenny María , Fuentes-Fuentes María del Mar 
Published: December 2023

Drawing on institutional and upper echelons theories, this study delves into the underexplored intersection of gender, context, and innovation performance among women entrepreneurs in Ecuador. Based on a sample of 45 women entrepreneurs, the study employs a fuzzy-set qualitative comparative analysis (fsQCA) and identifies six distinct paths to innovation performance. Contrary to initial expectations, our research findings substantiate that both institutional and social factors play a key role in fostering innovation in women-led firms in Ecuador. This innovation is facilitated by establishing close and frequent interpersonal connections, as well as by the age of the female entrepreneurs. Conversely, certain individual variables traditionally associated with innovation, such as education level or prior experience, manifest only sporadically. Our research enriches the discourse in gender and innovation studies by employing a multilevel approach and provides valuable insights into female entrepreneurial leadership’s contribution to advancing developing economies. JEL CLASSIFICATION: O32; J16
Biomechanical Fixation Analysis of Minimally Invasive Chevron Osteotomy
Authors: Nunes Gustavo Araujo , Carvalho Kepler A.M. , Mansur Nacime Salomao Barbachan , de Cesar Netto Cesar 
Published: December 2023

Category: Bunion Introduction/Purpose: The original fixation for minimally invasive Chevron-Akin ( MICA) was described with two screws: a proximal screw reaching two cortices before fixing the metatarsal head and a distal parallel screw that can reach only one cortical before fixing the head. Despite this, some authors questioned the need for two screws and were able to reproduce good results from this technique using only one screw to fix the osteotomy. Notably, no biomechanical studies evaluate this osteotomy's most stable and safe fixation. This work aims to perform a biomechanical analysis based on finite element analysis (FEM) to compare different MICA fixation configurations using screws. Our hypothesis is that the fixation of the original technique with two screws is the safest. Methods: A Three-dimensional (3D) virtual model of a foot computer tomography (CT) image was made using the Rhinoceros™ program. The element finite analysis was performed with the SimLab™ program using the Optistruct solver. From these 3D virtual models, an extracapsular chevron osteotomy with 130 degrees with 70% of lateral translation was done and fixated. Five internal fixation configurations with screws were used for fixation of MICA and assessed by FEM -: original MICA fixation with 2 screws, 2 intramedullary screws, 2 bicortical screws, 01 intramedullary screw, and 01 bicortical screw. The simulated 150 N and 300 N loads were applied to the middle foot. The FEM evaluated the total and localized displacements of the osteotomy site. For the analysis of stresses, the variables maximum principal (traction) and minimum principal (compression) were used. The equivalent von Mises stress (VMS -S) was used for the metallic implants and for the bone (VMS -O). Results: The classical fixation for MICA showed the lowest values for total and localized displacement, minimum and maximum total stress, and VMS-S and VMS-o in both conditions( 150 and 300 N). The localized displacement was statistically lower for MICA screws compared to the other fixation configurations (p < 0.05) The maximum total stress was statistically lower for MICA screws compared to the other fixation configurations (p < 0.05) Conclusion: The classical fixation for MICA yields better results in terms of total and localized displacement, minimum and maximum total stress, and VMS in both conditions. These results demonstrate that the classical fixation for MICA described in the original technique is biomechanically the most efficient and safe.
Comparable Outcomes of Cartiva Implant, Cheilectomy, and Fusion for Hallux Rigidus of the 1st Metatarsophalangeal Joint: A Matched Cohort Study
Authors: Comfort Spencer M. , Marchetti Daniel , Duncan Parker , Dornan Grant J. , Haytmanek C. Thomas , Clanton Thomas O. 
Published: December 2023

Category: Midfoot/Forefoot; Other Introduction/Purpose: The primary goal of treating hallux rigidus of the 1st metatarsophalangeal (MTP) joint of the foot is to reduce pain. Treatment options include cheilectomy, interposition arthroplasty, and arthrodesis for more severe disease. Recently, the use of a synthetic cartilage implant (Cartiva, Stryker Inc., MI, USA) has been introduced with the advantage of motion preservation. While a Level 1 study has demonstrated similar outcomes of fusion and Cartiva, other comparative studies have shown less favorable results for the Cartiva implant. The purpose of this study was to evaluate minimum 2-year patient reported outcomes (PROs) of the Cartiva implant for the treatment of hallux rigidus in the 1st MTP joint in comparison to a matched cohort of patients treated with fusion or cheilectomy. Methods: Patients >18 years old who underwent surgery for treatment of 1st MTP joint hallux rigidus with Cartiva implant, cheilectomy, or fusion performed by two surgeons (T.O.C. or C.T.H.) between January 2009 and January 2020 were identified. A 2:1 matched control cohort of patients who underwent cheilectomy or fusion was constructed using a nearest neighbor, greedy algorithm based on age, sex, prior surgery, and Coughlin osteoarthritis grade. Minimum 2-year follow-up was obtained with patients completing subjective questionnaires including Foot and Ankle Ability Measure (FAAM) with Activities of Daily Living (ADL) and Sport subscales, Short Form-12 (SF-12), Tegner activity scale, and patient satisfaction with surgical outcome. Demographics and patient-reported outcomes were compared between groups. Results: Follow-up was obtained for 22/27 (82%) Cartiva patients (mean age 54±19) at median 4.3 years and 41/49 (84%) control patients (mean age 58±11) at median 3.5 years. Prevalence of Coughlin grade was similar between Cartiva and control groups (6 vs 10 grade 1, 8 vs 15 grade 2, 2 vs 6 grade 4, 6 vs 10 grade 5; p=.93), respectively. There was no significant difference in median post-operative FAAM-ADL (96 vs 95, p=.53), FAAM-Sport (92 vs 89, p=.89), SF-12 PCS (56 vs 51, p=.054), SF-12 MCS (56.3 vs 57.5, p=.50), Tegner score (4 vs 3, p=.30), or patient satisfaction (9 vs 9, p=.91) between Cartiva and control cohorts, respectively. Revision surgery was required for 3 (14%) Cartiva patients and 4 (10%) control patients (p=.70). Conclusion: Patients treated with a Cartiva synthetic cartilage implant for 1st MTP joint hallux rigidus had similar patient-reported outcomes and revision rate compared to patients treated with cheilectomy or fusion for Coughlin grade 2-5 osteoarthritis.
Does Total Ankle Replacement Help to Improve Physical Activity in Patients 2 Year Post-Operatively? A Pilot Activity Monitoring Study
Authors: Hakeem Samir , Nicolas Andrea Pujol , Ramaskandhan Jayasree R. , Smith Karen M. , Siddique Malik 
Published: December 2023

Category: Ankle Arthritis Introduction/Purpose: Step count and activity monitoring are objective tools to measure improvement in functional ability in patients undergoing Total ankle replacement (TAR); this area is underexplored in literature. Activity monitoring sensors provide additional information on physical activity and energy expenditure in addition to step counts. These carried out in a real-life environment helps us to understand the impact of intervention in improving physical activity. The aim of this study was to study physical activity patterns in the community in patients who underwent TAR surgery. Methods: 10 patients who underwent a TAR between 2017 and 2019 were recruited. Exclusion criteria included previous reconstructive surgery, h/o infection, PVD, neurological disease and other joint replacements. Written consent was obtained. Patients were provided with ActivPAL TM activity monitor to wear over a 7-day period along with a self-reported diary to record activity patterns. This was carried out pre-operatively and 2 years. Data from sensors were downloaded and activity patterns were analysed with SPSS IBM 28 statistical package. Results: 10 patients (7 males, 3 females) were recruited. Mean age of patients were 65.16 years (52.4 to 78.1yrs).there was a trend for improvement in Sitting / Lying (hours) from 121.36 to 132.56 (p=0.367) and Standing (hours) 25.53 to 33.23 (p=0.411), although this did not achieve statistical significance. Step count (in hours) improved from 8.8 hrs to 10.8 hrs (p=0.05); Step count increased from 38544 to 47074 (p=041) from pre-op to 2 years. Energy expenditure (metabolic equivalents) improved from 192.3 to 219.5 (p=0.033). Conclusion: At 2 years post-operatively, TAR patients showed considerable improvement in step count and energy expenditure compared to pre-operative levels. The results of this novel study helps us to understand the functional improvements in terms of physical activity and energy expenditure gained from TAR surgery