bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE SYSTEMATIC REVIEW OF THE ASSOCIATION OF PREGNANCY OUTCOMES AND CHRONIC KIDNEY DISEASE
Authors: Supriyadi Agung , Andimapali Zulfikar , Fitria Adina , Whisnu Dewanegara Rahadiyan 
Published: February 2024

Background: Pregnancy as a metabolic stress test that might reveal underlying endothelial dysfunction and vascular illness. Maternal cardiovascular disease risk is heightened in cases of adverse pregnancy outcomes, including hypertensive disorders of pregnancy, gestational diabetes, and premature birth.
Aims : This systematic review is to review the association of chronic kidney disease to its outcomes at pregnant women.
Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as up-to-date as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed and SCIENCE DIRECT, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search brought up 661 articles, whereas the results of our search on SCIENCE DIRECT brought up 3.6314 articles. The results of the search conducted for the last year of 2014 yielded a total 12 articles for PubMed and 96 articles for SCIENCE DIRECT. In the end, we compiled a total of 5 papers, 4 of which came from PubMed and 1 of which came from SCIENCE DIRECT. We included five research that met the criteria.
Conclusion: In summary, an increased risk of chronic kidney disease was linked to exposure to unfavorable pregnancy outcomes, such as hypertensive disorders of pregnancy, gestational diabetes, and premature birth. Preeclamptic women had the highest chance of developing ESKD. To identify women who are more likely to develop kidney disease, especially following hypertensive disorders during pregnancy, a systematic strategy may be necessary to maximize the patients' long-term follow-up.
OVEREDUCATION E VIÉS DE GÊNERO: UM ESTUDO DE CASO SOBRE OS TÉCNICOS ADMINISTRATIVOS DA UNIVERSIDADE FEDERAL DE SÃO JOÃO DEL REI
Authors: ALINE CRISTINA CRUZ  , Elis Gonçalves Pinto  , Torres Daniela Almeida Raposo 
Published: February 2024

O artigo objetiva traçar o perfil dos técnicos administrativos efetivos da UFSJ, com atenção às diferenças entre homens e mulheres, com ênfase à sobre-educação e à satisfação no trabalho. A metodologia utilizada é Estudo de Caso e Análise de Conteúdo, a partir de aplicação de questionários combinada à Análise Documental do Plano de Carreira dos Cargos Técnico-Administrativos em Educação da UFSJ e Estatística Descritiva. Os resultados apontam que 93,3% dos respondentes são sobre-educados (62% são mulheres). Entre as técnicas, 58% são sobre-educadas e, entre os homens, o peso relativo é menor (36%), confirmando a discussão na literatura de que mulheres são mais propensas ao status de sobre-educadas. Ademais, 80% destas mulheres insatisfeitas com as atividades desempenhadas, no comparativo com a renda salarial, encontram-se na condição de sobre-educadas, confirmando a relação inversa prevista na literatura entre o status de sobre-educado e o patamar de satisfação laboral na UFSJ.
The Comparative Effects of Aqueous Extracts of Green Tea and Catechin on Inflammation, Apoptosis and Oxidative Stress in the Testicular Tissue of Diabetic Rats
Authors: Roshnavand Fatemeh , Hojati Vida , Vaezi Gholamhassan , Rahbarian Raheleh 
Published: February 2024

Diabetes mellitus causes damage to testicular tissue through inflammation and oxidative stress. Catechin has been reported to have anti-oxidant and anti-inflammatory properties. This study was performed to compare the effects of aqueous extracts of green tea and catechin on inflammation, apoptosis and oxidative stress in the testicular tissue of type-1 diabetic rats. In this experimental study, 48 male Wistar rats were divided into control group, and diabetic rats treated with aqueous extract of green tea (100 and 200 mg/kg) and diabetic rats treated with catechin (100 and 200 mg/kg) (n = 6/each group) for 4 weeks. Diabetes was induced by an intraperitoneal injection of 240 mg/kg Aloxan. Levels of glucose, CRP, TNF-α, IL-1β and IL-6, SOD, CAT, GPX, MDA, Bax and Bcl-2 were measured by Elisa in testicular tissue. Histomorphometric changes in testicular tissue were evaluated using E&H staining method. Treatment with aqueous extract of green tea (200 mg/kg) and catechin (100 and 200 mg/kg) resulted in a significant increase in Bcl-2, SOD, CAT, GPX levels and a significant decrease in serum glucose, Hs-CRP, TNF-α, IL-1β, IL-6, Bax and MDA levels, and significantly increased seminiferous tubules diameter and germinal cells count in testicular tissue compared to the diabetic control group. Treatment of diabetic rats with catechin had more improving effects on blood glucose, apoptosis, inflammation, lipid peroxidation, antioxidant enzymes, and histological structure of testis than green tea aqueous extract.
Significance of wetland and it’s dependent Avifauna in Bangoli Wetland Complex, Raipur District, Chhattisgarh, India
Authors: Bharos AMK , Vishwakarma Anurag , Verma Jageshwar , Bharos Akhilesh , Verma Dilip 
Published: February 2024

The Bangoli complex of wetlands is situated in central region of Chhattisgarh. This region is part of the Mahanadi river basin and is predominantly a plain area with the good number of tanks and village ponds. The geography of the area is mainly plains dotted with wetlands and sparse trees, thereby attracting both resident and migratory species. The aim of this study was to determine the avian diversity and composition in this complex, as no previous specific study was found undertaken, The available studies were either for specific species or covered the whole of the state. Our study spanned from the year 2015 to 2021. During the period the complex was visited intermittently covering all seasons and using standard methodology for observation and documentation, covering wetlands and their surroundings. This study area of the Bangoli complex comprised of five major wetlands and five smaller tanks, all situated within the area of about 20 sq km.. Our study revealed the presence of 293 species belonging to 20 orders and 69 families. The encountered species were categorized in Occurrence status as Resident (R)171 and Migratory(M) 122 in numbers respectively; Passerby mainly coastal species in Autumn and Spring seasons, Habitat used like Aquatic(A), Near Aquatic(NA)(Shore) , Grass and Arboreal (GA), Himalayan and sub-Himalayan species and Important Nesting species. Study also revealed presence of four new species unreported from central region. Also, 11 Threatened species as per Birdlife International- IUCN (2020) were identified in categories EN – 1, VU – 4, NT – 6. These wetlands are subjected to threats of the killing by snares and traps particularly in the winter season, commercial exploitations like fishing, cultivation , amusement, fodder collection and grazing,. The destruction of habitats caused by stone quarries and crushers, felling of trees are of another major concern.
Factors Associated with Providing Complete Basic Immunization in Toddlers
Authors: Handiny Febry , Tari Meysi Neldian , Oresti Syalvia 
Published: February 2024

Complete basic immunization (CBI) in toddlers is a crucial aspect of public health. It can protect children from infections that can kill or disable them. Nevertheless, the CBI is still low in the working area of Lubuk Buaya Public Health Center, standing at 49.7%, while the national target achievement is 95%, indicating a disparity of 45.3%. The purpose of this study was to determine the factors associated with the provision of complete basic immunization to toddlers in Pasia Nan Tigo Village, Lubuk Buaya Public Health Center Working Area. The type of research was quantitative with a cross-sectional design. The researchers conducted the study from March to August 2023. The population of this study were mothers who had toddlers who were residing in Pasia Nan Tigo Village, as many as 105 people. Accidental sampling was used to collect 51 respondents. We obtained data by questionnaire and interview. We analyzed the data using the chi-square test. The result found that 58.8% of respondents did not provide complete basic immunization to toddlers, 64.7% of respondents had a low level of knowledge, 60.8% of respondents did not have available facilities and infrastructure, 62.7% of respondents stated that the role of health workers was not satisfying, and 62.7% of respondents did not get family support. The level of knowledge, availability of facilities and infrastructure, the role of health workers, and family support were associated with the provision of complete basic immunization in toddlers. Knowledge, facilities and infrastructure, health workers, and family support are factors that can influence the provision of complete basic immunization for toddlers. It is expected for the head of the Lubuk Buaya Public Health Center to complete Integrated Healthcare Center tools such as reading materials, brochures, and leaflets so that Integrated Healthcare Center services can motivate cadres to change the mother’s behavior.
Keywords: CBI, Knowledge, Facilities and Infrastructure, Health Worker, Family Support ,
Double‐Step nerve stimulation test for myasthenic block: Sensitization of postactivation exhaustion by ischemia
Authors: Desmedt John E. , Borenstein Samuel 
Published: January 2005

AbstractA new, double‐step test is described that increases the yield of diagnostically useful data in patients with localized ocular or bulbar paresis who may have myasthenia gravis. The first step involves a program of supramaximal stimulation of the ulnar nerve at a rate of 3 per second for four minutes while electrical responses are recorded in four muscles of the hand and forearm to detect decrements and postactivation exhaustion. The second step delivers the same program under ischemia and elicits decrements from the subclinically involved muscles that reacted normally to the first step. Control tests in a large number of normal subjects established the conditions that efficiently challenge the muscles with a reduced safety factor for neuromuscular transmission while avoiding false‐positive results. The test involves the hypoxic failure of neurochemical processes. The ulnar flexor muscle of the wrist in athletic normal men was surprisingly more susceptible to ischemic exercise than the other normal muscles.The diagnostic uses of the double‐step test are documented in patients in whom the orbicular muscle of the eye and the proximal limb muscles reacted normally, and the concept of occult myasthenia gravis is discussed.
Eosinophilic polymyositis
Authors: Layzer Robert B. , Shearn Martin A. , Satya‐Murti Saty 
Published: January 2005

AbstractIn 3 patients with subacute polymyositis, muscle biopsies were remarkable for showing abundant infiltration by eosinophils. In each case the inflammatory myopathy was part of a systemic illness known as the hypereosinophilic syndrome (HES). The systemic manifestations included eosinophilia, anemia, hypergammaglobulinemia, vascular involvement (subungual petechiae, livedo reticularis, Raynaud's phenomenon), skin rash and subcutaneous edema, pulmonary infiltrates and pleuritis, cardiac involvement (congestive heart failure, arrhythmias, heart block, pericarditis, myocardial and endocardial fibrosis), and peripheral neuropathy. Myopathy has received scant mention in previous reports of HES, but 30% of the patients had neurological symptoms such as encephalopathy, multiple cerebral infarcts (possibly embolic in origin), peripheral neuropathy, and mononeuropathy multiplex. The prognosis is poor, average survival being only nine months after the onset of symptoms; but 2 of our patients, and a few reported by others, have responded well to corticosteroid treatment.
Spinal cord sarcoidosis
Authors: Day Arthur L. , Sypert George W. 
Published: January 2005

AbstractThree patients with spinal cord involvement by sarcoid are described and the literature is reviewed. Fifteen patients with histologically verified sarcoidosis involving the spinal cord presented with progressive myelopathy due to tumor. Myelography variously showed an extramedullary intradural mass; an intramedullary mass; a thinned, atrophic cord; or normal configuration.Although laminectomy and biopsy are often required to establish the diagnosis, treatment is medical, using corticosteroid drugs. Treatment seldom leads to complete recovery, but neurological deficits may stabilize or improve.
Developments in the pharmacology and therapeutics of parkinsonism
Authors: Calne D. B. 
Published: January 2005

AbstractAdvances in synaptic pharmacology have led to new approaches to understanding and attempting to alleviate the disturbances in neurotransmission that occur in parkinsonism. Techniques which were initially developed to elucidate normal synaptic phenomena are being employed to screen potential therapeutic agents for efficacy, relative potency, and neurotoxicity and to analyze the mechanism of action of antiparkinsonian drugs. In vitro methods utilizing striatal tissue include the assay of dopamine release, the determination of active dopamine reuptake, the displacement of ligands from dopamine receptors, and the stimulation of dopamine‐sensitive adenylate cyclase. In vivo test systems in rats comprise alleviation of the reserpine syndrome, induction of stereotypic behavior, measurement of turning after unilateral nigrostriatal lesions, evaluation of regional changes in the concentration of dopamine and its metabolites, and recording of single‐unit responses in the brain. With these tools, it is proving possible to sustain progress in the search for improved treatment, exemplified by current experimental studies with dopaminergic agonists and selective inhibitors of monoamine oxidase isoenzymes. The pursuit of practical applications has been accompanied by conceptual advances, such as the proposal that cyclic nucleotides are “second messengers” in the nigrostriatal pathway and the recognition of certain amino acids and peptides as synaptic transmitters or modulators in the basal ganglia.
Suppression of essential tremor by propranolol: Correlation of effect with drug plasma levels and intensity of beta‐adrenergic blockade
Authors: McAllister R. G. , Markesbery William R. , Ware Ray W. , Howell Shirley M. 
Published: January 2005

AbstractPropranolol was given intravenously to 6 adult patients with essential tremor, using a bolus‐infusion regimen for rapid production and maintenance of predicted drug plasma levels. Tremor in the outstretched hand was quantitated by integration of the waveform signal recorded from a miniature accelerometer. Propranolol had no effect on tremor frequency (6 to 8 cps), but it suppressed tremor amplitude in all patients in direct proportion to the drug's plasma concentration and to the intensity of beta‐adrenergic blockade produced. Among this group of patients the maximal tremor decrease occurred at plasma levels of about 100 ng per milliliter and varied widely between individuals (18 to 85%), implying that the efficacy of propranolol therapy in essential tremor depends on both the plasma drug level and the innate sensitivity of the disorder in the individual patient.
Prolonged focal epilepsy and hypoxemia as a cause of focal brain damage: A case study
Authors: Knopman David , Margolis George , Reeves Alexander G. 
Published: January 2005

AbstractA 48‐year‐old woman developed epilepsia partialis continue (EPC) involving the right arm and leg, which lasted for four weeks until she died. Systemic hypoxia associated with chronic obstructive pulmonary disease and acute pneumonia complicated her hospital course. At autopsy, diffuse cortical changes resembling the sequelae of ischemic anoxia were observed in the left cerebral hemisphere. The right cerebral hemisp here and cerebellum were minimally involved. No other significant pathological processes could be identified in the central nervous system, and the cerebrovascular system was free of obstructive lesions. It is proposed that the left‐sided damage was precipitated by the increased metabolic demand of the cerebral cortex associated with the EPC, with which autoregulatory circulatory responses were unable to cope in a patient with underlying hypoxia.
Basilar artery occlusion in a 10–year–old boy
Authors: Ackerman Edward S. , Levinsoh Morris W. , Richards David , Bonstelle Charles , Mitchell Mark 
Published: January 2005

AbstractA 10‐year‐old boy developed vertigo and signs of brainstem dysfunction. Arteriography demonstrated complete occlusion of the basilar artery. No cause of the occlusion could be determined. This case emphasizes the rarity of basilar artery occlusion during childhood. Its differential diagnosis is discussed.
Cerebral vasculitis in coccidioidal meningitis
Authors: Kobayashi Ronald M. , Coel Marc , Niwayama Gen , Trauner Doris 
Published: January 2005

AbstractCerebral vasculitis producing focal central nervous system manifestations was observed in 2 patients with meningitis due to Coccidioides immitis. Cerebral angiography demonstrated the characteristic changes of arteritis, including irregular narrowing of arteries at the base of the brain in 1 patient and occlusion of a middle cerebral artery branch in the other. Pathological examination of the brain in the latter patient revealed extensive basilar meningitis along with prominent vasculitis and organisms. One patient responENd to intrathecal and intravenous amphotericin B treatment combined with a ventriculopleural shunt, the other died despite amphotericin B therapy.
Cerebral‐cerebellar paroxysmal activity in experimental focal seizures
Authors: Caveness William F. , Kosaka Kenji , Hosokawa Shinichi , O'Neill Raymond R. 
Published: January 2005

AbstractFocal seizures were induced in 14 monkeys by injection of 25,000 units of penicillin into area 4 of the right cerebral motor cortex. Prior to and throughout the development and propagation of the seizures, bipolar recording of the surface electrical activity was obtained from an array of four pairs of platinum electrodes over the right precentral gyrus of the cerebral cortex and a similar array over the paravermal area of the lobulus simplex and the anterior lobe of the left cerebellar cortex.There was a very close correlation between the initial and subsequent rhythmic spike activity from the right cerebral to the left cerebellar cortices, as evidenced by: (1) an identical time of onset of spike activity in 11 of 14 monkeys, as recorded by the ink‐writing equipment; (2) a comparable increase in frequency and complexity of waveform with progression of paroxysmal activity; and (3) an appropriate and simultaneous somatotopic representation of initiation and progression of the paroxysmal activity along the motor strip of the right motor cortex and the left paravermal area of the cerebellar cortex. The activity in both was consonant with that from electromyograms of the left face, arm, and leg.
Huntington's disease—growth of fibroblast cultures in lipid‐deficient medium: A preliminary report
Authors: Menkes John H. , Hanoch Amalia 
Published: January 2005

AbstractWhen skin fibroblast cultures derived from subjects with Huntington's disease (HD) were grown in medium supplemented with lipid‐deficient serum (LDS), growth rates were less than those of control cultures. The mean percentage increase in generation time for nine control cultures incurred by using LDS rather than fetal calf serum (FCS) was 8.0%. Four cultures from 2 patients with HD failed to grow in LDS but grew well in medium supplemented with FCS. In nine other cultures derived from 7 patients with HD the mean percentage increase in generation time incurred by using LDS was 88.1%. Returning cultures to FCS or adding a mixture of linoleic and linolenic acids restored the growth rate of HD cultures to normal.
Botulism: Electrophysiological studies
Authors: Oh Shin Joong 
Published: January 2005

AbstractIn a patient with botulism type B, electrophysiological studies showed: (1) a pattern in the repetitive nerve stimulation test resembling that found in the Eaton‐Lambert syndrome but without any significant increment at high rates of stimulation or posttetanic exhaustion phenomenon; (2) a prominent response to guanidine hydrochloride; (3) a short mean duration of motor unit potentials that reversed with recovery; (4) a mild, prolonged latency and low amplitude of the H‐reflex; (5) mild peripheral nerve dysfunction; and (6) a long‐lasting persistence of abnormalities beyond the time of clinical recovery. The literature reports two types of responses in the repetitive nerve stimulation test in botulism: in the severe form one obtains a low‐amplitude muscle potential, a decremental response at low rates of stimulation, and an insignificant incremental response at high rates of stimulation; in the mild form a normal amplitude of muscle potential occurs together with a normal response to low rates of stimulation and a significant incremental response at high rates of stimulation.
Speech disorders in cerebellar disease
Authors: Lechtenberg Richard , Gilman Sid 
Published: January 2005

AbstractThe areas of cerebellar damage most commonly associated with dysarthria were sought by reviewing the clinical, radiographic, surgical, and autopsy findings in patients with nondegenerative cerebellar disease. Case histories on 162 patients with focal cerebellar lesions were reviewed. All but 15 of the patients underwent surgery, and 28 had autopsies. Thirty‐one of the 122 patients with adequate descriptions of speech had dysarthria. Twenty‐two of these 31 dysarthric patients had exclusively or predominantly left cerebellar hemisphere disease; 7 had right hemisphere disease; and 2 had vermal disease. Only 19 of 41 patients with exclusively or predominantly left hemisphere disease had had normal speech before surgery. Dysarthria developed in isolated cases following cerebellar resections extending into the paravermal segments of the left hemisphere. There was no correlation between the extent of vermal damage and development of abnormal speech. Cerebellar speech function was most commonly affected with damage to the superior portion of the left cerebellar hemisphere.
The distribution of myelin basic protein in central nervous system lesions of multiple sclerosis and acute experimental allergic encephalomyelitis
Authors: Whitaker John N. 
Published: January 2005

AbstractTo obtain more information about early events in central nervous system myelin injury in multiple sclerosis (MS), a comparative study was conducted of the distribution of myelin basic protein (BP) in tissue lesions of both MS and experimental allergic encephalomyelitis (EAE). Sixteen postmortem specimens containing lesions from 4 persons with MS and the brains of 14 guinea pigs with acute EAE induced with BP were studied. Cryostat sections of quick‐frozen material were fixed, treated with rabbit antibody to BP, and processed by immunoperoxidase techniques. The reaction of antibody to BP was reduced or absent in MS lesions but normal in uninvolved surrounding tissue. Alterations in BP generally paralleled changes in staining of myelin by histological methods. Marked diminution of reactivity with anti‐BP occurred in early lesions of MS and extended far beyond any identifiable inflammatory elements. In both parenchyma and perivascular areas, lipid‐laden macrophages in MS plaques frequently contained BP material in addition to a variable amount of endogenous peroxidatic activity. Compared with MS, BP was relatively well preserved in brains of guinea pigs with EAE. At the light microscopy level, normalappearing patterns of BP existed adjacent to the perivascular cellular infiltrates, and macrophages containing BP material were rare. The results of this study suggest differences between MS and acute EAE in both removal of BP from the central nervous system and its subsequent disposal.