bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metallkomplexe mit Polyaminen XII: Mit cis‐cis‐1,3,5‐Triaminocyclohexan
Authors: Brauner Phyllis A. , Schwarzenbach G. 
Published: December 2004

AbstractThe 1:1‐metal complexes of cis‐cis‐1,3,5‐triamino cyclohexane (denoted by B) have been investigated. CuII, ZnII and AgI are forming a protonated complex of composition MHB3+ and AgHB2+ respectively, and their stability shows them to be chelates with the cyclohexane ring in the boat form. At higher pH‐values deprotonation to MB2+, AgB+ takes place. With silver a bimetallic complex Ag2B2+ is also formed. Complex formation with Ni2+, Co2+ and Cd2+ at equimolecular concentrations of 10−3 M is negligible.
Heilmittelchemische Studien In Der Heterocyclischen Reihe 35. Mitteilung. Über Sydnonimine. I. Herstellung und Eigenschaften von Sydnonimin‐Salzen
Authors: Daeniker H. U. , Druey J. 
Published: December 2004

AbstractThe synthesis and properties of different types of sydnonimine salts have been investigated. The stability of these salts containing different types of acid components has been examined, and their behaviour towards bases and acids and on catalytic hydrogenation is described. The UV.‐ and NMR.‐spectra of a number of these compounds are given and discussed.
Reaktionen von Steroid‐Hypojoditen IV. Über den Verlauf intramolekularer Substitutionsreaktionen, insbesondere bei 2β‐ und 4β‐Hydroxysteroiden. Über Steroide, 192. Mitteilung
Authors: Heusler K. , Kalvoda J. , Wieland P. , Anner G. , Wettstein A. 
Published: December 2004

AbstractFrom 4β‐ as well as from 2β‐hydroxy‐steroids 19‐hemiacetal derivatives are formed in the «hypoiodite reaction», especially with lead tetraacetate and iodine, whereas 6β‐hydroxy‐steroids give 6β,19‐ethers exclusively(1). This behaviour is explained on the basis of the differences in the relative orientation of the hydroxyl groups towards the conformationally fixed 19‐CH2I group in the iodohydrin intermediates.
Recherches sur la formation et la transformation des esters XXXVIII. Sur la phosphonylation de divers types d'alcools
Authors: Cherbuliez Emile , Baehler Br. , Probst H. , Rabinowitz J. 
Published: December 2004

AbstractThe preparation of the phenylphosphonic monoesters of tribromoethanol, propargyl alcohol, glycerol, choline, menthol, and borneol is described.
Mizellenbildung in wässerigen Lösungen der sulfatierten Polyäthylenoxid‐Kondensaten des Nonylphenols
Authors: Milićević B. 
Published: December 2004

AbstractThe critical micelle concentration of detergents composed of ethoxylated nonyl‐phenyl sulfates has been determined by the surface tension method. Although the effect of ethylene oxide chain length on the critical micelle concentration follows a linear expression similar to that of non‐ionic detergents, the influence of temperature on the cloud point suggests a basic difference between the micelles of ethoxylated nonylphenols and those of their sulfates.
Über die Konstitution des Biflorins, eines o‐Chinons der Diterpen‐Reihe
Authors: Comin J. , de Lima O. Gonçalves , Grant Heather N. , Jackman L. M. , Keller‐Schierlein W. , Prelog V. 
Published: December 2004

AbstractChemical and spectroscopic evidence leads to constitution III for the bluish‐red antibiotic biflorin, C20H20O3 obtained from Capraria biflora L.
Recherches sur l'accumulation et la toxicité du radium et du radiostrontium dans le corps humain. III. Courbes d'élimination du strontium 90
Authors: Wenger Pierre , Soucas Kyriacos 
Published: December 2004

AbstractThe urinary excretion of two persons contaminated by 90Sr was followed up for 34 weeks. The excretion curve of one of these persons, whose contamination ceased 940 days before the beginning of the analyses, and which corresponds to a period of slow elimination, indicates a half‐time value of 2502 days. The curve of the other one, which has been taken just after contamination ceased and which corresponds therefore to a period of more rapid elimination, indicates a half‐time value of 337 days.
Reaktionen von Steroid‐Hypojoditen V Einwirkung von Blei(IV)‐acetat‐Jod auf 11β‐Hydroxysteroide. Über Steroide, 195. Mitt
Authors: Kalvoda J. , Heusler K. , Anner G. , Wettstein A. 
Published: December 2004

AbstractThe “hypoiodite reaction” with 11β‐hydroxysteroids of the 5αH, 5βH und Δ5 series is described. Both methyl groups C‐18 and C‐19 are substituted, and products of single and double radical attack are found. In the case of 5βH steroids the reaction at C‐19 gives 11β, 19‐ethers exclusively. The results are explained on the basis of the differences in the steric arrangement of the reactive centres in the intermediates of type C.
Notiz über die Alkaloide von Kopsia fruticosa
Authors: Guggisberg A. , Govindachari T. R. , Nagarajan K. , Schmid H. 
Published: December 2004

AbstractUnter sehr milden Aufarbeitungsbedingungen liessen sich aus getrockneten Blattern von Kopisia fruticosa (KER.) A. DC., neben Kopsin, Fruticosin und Fruticosamin, Decarbomethoxy‐kopsin und Decarbomethoxy‐isokopsin isolieren. Fruticosin und Fruticosamin sind Isomere der Formel C22H24O4N2 und lassen sich gegenseitig ineinander umwandeln; das chromophore System und die Natur der funktionellen Gruppen dieser beiden Alkaloide wurden abgeklärt.
Über Pterinchemie. 6. Mitteilung. Ein in 9,10‐Stellung (ortho)‐dihydriertes Pterin: 9,10‐Dihydropterin‐8‐carbonsäureamid
Authors: Viscontini M. , Merlini L. , von Philipsborn W. 
Published: December 2004

AbstractProtonenresonanz‐Spektren zeigen, dass ein fruher von uns als para‐Dihydro‐verbindung (11) aufgefasstes Pterinamid in Wirklichkeit die Struktur eines 9,10‐(ortho)‐Dihydropterin‐8‐carbonsaureamids (IV) besitzt.
19‐Norsteroide IV. Über die reduktive Ätherspaltung bei 5α‐Halogen‐6β, 19‐oxido‐steroiden. Über Steroide, 198. Mitteilung
Authors: Kalvoda J. , Heusler K. , Ueberwasser H. , Anner G. , Wettstein A. 
Published: December 2004

AbstractThe reductive cleavage of the ether bridge of 5α‐chloro‐ and 5α‐bromo‐6β, 19‐oxido‐steroids to 19‐hydroxy‐Δ5‐steroids has been studied : Whereas 5α‐bromo‐6β, 19‐ethers could be reduced under mild conditions, i. e. with zinc and acetic acid, 5α‐chloro‐6β, 19‐ethers could only be cleaved with lithium and liquid ammonia. However, the latter steroids with an additional electronegative substituent in 19‐position, namely 5α‐chloro‐6β, 19‐hemiacetals and ‐lactones, were smoothly converted into Δ5‐19‐aldehydes and Δ5‐19‐acids, respectively, by the action of zinc and acetic acid. The Δ5‐steroid‐3 9‐oic acids obtained could be decarboxylated thermally to Δ5(10)‐19‐norsteroids.
Thermodynamik der Färbevorgänge. I. Absorptionsmodelle
Authors: McGregor R. 
Published: December 2004

AbstractA brief discussion is given of the selection of the reference states for defining the relative activity of a desperse dye in the fibre phase and in the solution phase. Contrary to recent findings2), it is suggested that the application of the Flory‐uggins equations for polymer solutions to desperse dyeing equilibria leads to the prediction that the adsorption isotherm will be linear for concentrations expressed in molalities. Furthermore, the partition coefficient should not vary with the molecular weight of the polymer or fibre phase.
Zur Kenntnis ätherischer Öle. 1. Mitteilung. Zur Kenntnis des Mandarinenschalen‐Öls (Citrus reticulata BLANCO, bzw. Citrus nobilis var. deliciosa SWINGLE „Mandarin”︁)
Authors: Kugler E. , Kováts E. sz. 
Published: December 2004

AbstractThe volatile part of the essential oil of mandarine peel has been analysed. The crude, pressed oil was first divided into various fractions, mainly with the aid of physical methods. On distillation of these fractions the pure components could be isolated by preparative gas chromatography.
De la chimie des Ptérines. 7e communication. Obtention de dimères à partir de ptérines hydrogénées
Authors: Viscontini M. , Piraux M. 
Published: December 2004

AbstractPar oxydation de ptérines auxquelles est attribuée, à titre d'hypothèse de travail, la structure de ptérines para‐dihydrogénées, on obtient 3 paires de ptérines probablement dimères.
Photochemische Reaktionen. 22. Mitteilung. UV.‐Bestrahlung von 11‐Oxo‐Steroiden III. Zur Beeinflussung der (11 → 19)‐Cyclisation durch sterische Faktoren
Authors: Iriarte J. , Schaffner K. , Jeger O. 
Published: December 2004

AbstractThe photochemical cyclisation of 11‐keto steroids to 11β, 19‐cyclo‐11‐hydroxy compounds is strongly influenced by steric factors. The presence of a gem‐dimethyl group at C‐4 gives rise to a marked improvement in the yield of the cyclic product. The nature of this steric interaction is briefly discussed.
Heilmittelchemische Studien in der heterocyclischen Reihe. 42. Mitteilung. 2,3,4,5‐Tetrahydro‐1,4‐benzoxazepine
Authors: Schenker K. , Druey J. 
Published: December 2004

AbstractThe reaction of 2‐(2′‐chloroethoxy)‐acetophenone (I) with non‐hindered primary aliphatic amines is shown to give 4‐alkyl‐5‐methylene‐2.3.4.5‐tetrahydro‐1.4‐benzoxazepines (IV) which can be smoothly hydrogenated to the corresponding 5‐methyl derivatives VI. Steric limitations of this ring closure are discussed.
Chinazoline und 1,4‐Benzodiazepine. XIII. Mitteilung. Synthese von 7‐Carbalkoxy‐, 7‐Carbamoyl‐ und 7‐Cyan‐5‐phenyl‐1,4‐benzodiazepin‐Derivaten
Authors: Sternbach L. H. , Saucy G. , Smith F. A. , Müller M. , Lee J. 
Published: December 2004

AbstractThe synthesis of several 1.4‐benzodiazepine derivatives with a carbalkyxy, a carbomoyl or a cyano group in position 7 via the corresponding o‐aminobenzophenones is described.
Über die Herstellung von 1,1‐Chlorfluorcyclohexen und 1‐Fluorcyclohexen
Authors: Hopff H. , Valkanas G. 
Published: December 2004

AbstractReaction of hydrogen fluoride with 1‐chloro‐cyclohexene in ether solution at 0° C gave 1‐fluoro‐1‐chloro‐cyclohexane in 96% yield. The latter, when treated in the presence of cobalt naphthenate with a stream of air, is readily converted to 1‐fluoro‐cyclohexene.
Contribution à l'étude du système quinaire H+Na+K+Cl−PO4− − −H2O. I. Généralités et systèmes ternaires NaClKClH2O, KClKH2PO4H2O, NaClNaH2PO4  H2O et NaH2PO4KH2PO4H2O
Authors: Brunisholz G. , Bodmer M. 
Published: December 2004

AbstractA new technique suitable for the determination of solubilities at temperatures above 50° has been described. The ternary systems NaClKClH2O and KClKH2PO4H2O have been reinvestigated and solubility isotherms of the systems NaClNaH2PO4H2O and KH2PO4NaH2PO4H2O have been established at various temperatures.
Contribution à l'étude du système quinaire H+Na+K+Cl−PO4− − −H2O. II. Le diagramme de solubilité du système quaternaire Na+K+Cl−H2PO4−H2O
Authors: Brunisholz G. , Bodmer M. 
Published: December 2004

AbstractThe solubility isotherms of the quarternary system Na+K+Cl−H2PO4−H2O are given for O° 25° and 75°. Additional data have been used for the establishment of the polytherms, between 0° and 100°, of the two «3 salt lines» (saturation with NaCl + KCl + KH2PO4, and NaCl + KCl + a sodium dihydrogenophosphate) and of two «2 salt surfaces» (saturation with NaCl + KCl, and NaCl + KH2PO4). The parameters of the two invariant points of the system have been established by interpolation. The salts NaCl and KH2PO4 form the «stable salt pair» at all temperatures between 0° and 100°.
Die Löslichkeit von Metallsulfiden I. Schwarzes Quecksilbersulfid
Authors: Schwarzenbach G. , Widmer Michael 
Published: December 2004

AbstractThe total concentration of dissolved mercury in equilibrium with solid HgS and in the presence of excess sulfide (present in the form of H2S, HS‐ and S2− has been determined radiochemically and gravimetrically. The difficult problem of the clean separation of the precipitated HgS from the solution could be solved by very slow filtration of large quantities of the suspension through a small porous plate under constant pressure. The solubility at a constant concentration of excess sulfide (=0,019 molar) as a function of pH is demonstrated in figure 1. The solubility is due to the complex Hg(SH)2 below pH 5, the complex HS‐Hg‐S‐ between pH 6 and 8, and the complex HgS above pH 9. The solubility produce of black HgS, the stability constants of the complexes, and the two acidity constants of Hg(SH)2 are given in the last section of the paper.
Phtalocyanine in wässeriger Lösung IV. Kinetik und Mechanismus der Metallkomplexbildung
Authors: Schiller I. , Bernauer Klaus 
Published: December 2004

AbstractThe mechanism of metal ion incorporation into phthalocyanine tetrasulfonic acid has been investigated. The rate determining step of these reactions is the pyrrole‐NH‐dissociation of the ligand, which is catalysed by particles like MeOH+.
Die Analyse «scheinbar einfacher» kernmagnetischer Resonanzspektren
Authors: Diehl P. 
Published: December 2004

AbstractThe theory of observed spectra that give less than the theoretical number of transitions, i.e. apparently simple spectra, is studied. The general conditions for the existence of such spectra of the type AB … RX … are discussed in terms of effective LARMOR‐frequencies. Explicit experimental conditions for which observed spectra are apparently simple are given for spectra of the type ABX as well as A2B2X.
9. 3,4,7,8‐Tetrahydro‐2H‐6H‐pyrimido[2,1‐b]1,3‐oxazin‐2,4‐dione Derivate eines neuen Ringgerüstes 2. Mitteilung über Struktur und Reaktivität heterocyclischer Verbindungen
Authors: Gmünder J. , Lindenmann A. 
Published: December 2004

AbstractHexahydropyrimidone‐(Z), reacted with dialkylmalonic acid dichlorides, does not yield malonylhexahydropyrimidones 111, but carboxylic acid derivatives V, the structure of which is confirmed by various reactions. Splitting off of water from V with dicyclohexyl‐carbodiimide, again does not yield malonylhexahydropyrimidones 111, but ‐as may be shown by the NMR.‐spectrum ‐the isomeric 3,4,7,S‐tetrahydro‐ 2H‐6H‐pyrimido[Z21‐b]l, 3‐oxazine‐2,4‐diones X. Various reactions, as well as the spectral behaviour of these compounds in the infra‐red and ultra‐violet ranges, are discussed. These compounds are chemically similar to acid anhydrides and azlactones.
Papierchromatographische Prüfung der Sekrete von Bufo melanostictus Schneider und Bufo asper Gravenhorst Krötengifte, 30. Mitteilung
Authors: Iseli E. , Weiss Ek. , Reichstein T. , Chen K. K. 
Published: December 2004

AbstractAccording to paperchromatograms the paratoid secretion ofBufo melanostictus SCHNEIDER was found to contain 12 bufogenins. Three of these (M, Bt und H) have been identified with the known genins Marinobufagin, Bufotalin and Hellebrigenin. Two other ones (X1 and X2) are possibly identical with Resibufogenin and Bufalin. By the same method the secretion of Bufo asper GRAVENHORST was found to contain 9 bufogenins. A1 again is possibly identical with Resibufogenin; two others have been shown to be Marinobufagin (M) and Bufotalin (Bt). One genin (AZ), present in relatively large amount, should certainly be a new substance.
Präparative Darstellung und qualitative Eigenschaften von Xenontetrafluorid
Authors: Schumacher Ernst , Schaefer Manfred 
Published: December 2004

AbstractA method for continuous preparation of XeF4 is described. Several chemical properties of the substance are qualitatively studied. Among these a reaction with acetic acid or acetic anhydride leads to a crystalline compound, whereas the product formed between XeF4, and BF3, yields a violet solid, stable below −100°C.
Über pyrophores Eisen
Authors: Feitknecht W. , Durtschi A. 
Published: December 2004

AbstractIf iron oxides are reduced at temperatures ranging from 300° to 500°C, Fe3O4, is first formed, if not already present, and this goes directly over into iron. The nucleation of iron is slow, and if the oxide is finely crystalline, the iron nuclei grow by diffusion of iron atoms from many oxide crystals already at a temperature of approximately 300°C. The iron crystals sinter together to form irregular secondary particles. ‐ Responsible for the pyrophorous behaviour is the specific surface. Self‐ignition occurs when this surface is greater than approximately 3 m2/g. Pyrophorous iron can be inactivated with a mixture of N2 low in 02, an oxide layer being formed approximately 13 Å, i.e. ca. 6 02−‐layers, thick. An estimation of the heat produced on forming this layer and of the resulting temperature increase leads to a value which is in agreement with the ignition temperature of inactivated iron powder with a specific surface of approx. 3 m2/g.
Strahlungschemie der Kohlenwasserstoffe 11. MitteilungToluol‐α‐d3
Authors: Hoigné Jürg , Gäumann Tino 
Published: December 2004

AbstractThe products produced by γ‐rays in liquid toluene‐α‐d3 are compared with those measured in toluene‐α‐d0. The overall polymer‐formation is hardly affected by the deuteration but the yield of the individual dimeric compounds is characterised by the fact that the formation of the benzyl radicals becomes about 40% of the value in protonated toluene. This results in a benzyl formation of 17%, a benzyl‐toluene formation of 400%, and an increased yield of all the bitolyls as compared with the values found for toluene‐α‐d0.
Über die Aktivierung des Biotins
Authors: Valloton M. , Leuthardt F. 
Published: December 2004

AbstractBiotin hydroxamate is formed when [14C]‐biotin is incubated with a partially purified extract of chicken liver in the presence of ATP, Mg++ and an excess of hydroxylamine. Free biotin and the hydroxamate have been separated by chromato‐ graphy on anion‐exchange paper. Hence we conclude that biotin was activated to form biotin‐adenylate.
Recherches sur la formation et la transformation des esters L Réaction entre acide phosphoreux et alcools de divers types, notamment diols
Authors: Cherbuliez Emile , Prince R. , Rabinowitz J. 
Published: December 2004

AbstractReacted with phosphorous acid under reduced pressure, the linear 1,ωdiols (ω= 3 to 8) yield a mixture of the corresponding phosphorous diprimary diesters H,2O2‐R‐OPO2, H2, and ω‐hydroxy‐1‐alkyl monoesters. Cyclohexane‐1,4‐diol reacts in the same manner. The linear diols with ω = 2, 9, 10 or 32, as well as cyclohexane‐ l12‐diol, yield the phosphorous monoesters exclusively. Halogenated alcohols, cyclohexanol, and glycerol, reacted with phosphorous acid, yield the corresponding phosphorous monoesters. Phosphorous monoesters and diprimary diesters are stable in aqueous solutions between pH 3 and pH 9, but are very quickly hydrolized in strongly acidic or alka‐ line solutions.
Zur Kenntnis des Kohlenstoffringes. 78. Mitteilung Untersuchung von trans‐1‐Methl‐cyclodecen‐(1)‐on‐(6) auf Atropisomerie mittels einer asymmetrischen Synthese aus (1s, 9R, 10R)‐10‐Hydroxy‐1‐methansulfonyloxy‐9‐methyl‐decalin
Authors: Westen H. H. 
Published: December 2004

AbstractRepetition of WHARTON'S stereospecific synthesis [6] of trans‐l‐methyl‐l‐cyclo‐decen‐6‐one has led to the elucidation of the hitherto partly unknown configuration of the intermediates.
Die Cardenolide der Samen von Strophanthus vanderijstii Staner. 2. Mitteilung. Trennung der wasserlöslichen Glykoside Glykoside und Aglykone, 254, Mitteilung
Authors: Brenneisen K. , Euw J. V. , Tamm Ch. , Reichstein T. 
Published: December 2004

AbstractThe presence of 19 cardenolides (G, H, J, K, L1 L2 L3 M1, M2 M3 M4 M5, O, P1, P2, Q1, Q2, Q3 and R) could be traced in the water‐soluble parts obtained after fermentation from the seeds of Stropkalzthus vartderijstii STANER. Eight of these (G, H, J, K, L1, L2, L3 and M1) could be isolated in crystal line form, and two (O and P2) in amorphous but homogeneous form, according to paper chromatography. P2 M2 and M3 were obtained as crystalline O‐acetyl derivatives. The presence of M4 M5 and of three components in the Q group became evident only after degradation reactions.
Über die Herstellung von 2‐Amino‐5‐Pyrazincarbonsäure und Derivaten
Authors: Felder E. , Pitré D. , Grabitz E. B. 
Published: December 2004

Abstract2‐Acetylaminoquinoxaline was oxidized with potassium permanganate to 2‐acetyl‐aminopyrazine‐5,6‐dicarboxylic acid which yielded 2‐aminopyrazine‐5,6‐dicarboxy‐lic acid by acid hydrolysis. This acid was decarboxylated in high yield to 2‐amino‐pyrazine‐5‐carboxylic acid which was further converted into its methyl ester, ethylester and amide, and into 2‐hydroxypyrazine‐5‐carboxylic acid.
BECKMANN‐Umlagerung und Fragmentierung. 1. Teil. Mechanismus sowie Nachweis der Zwischenstufen Fragmentierungsreaktionen. 7. Mitteilung
Authors: Grob C. A. , Fischer H. P. , Raudenbusch W. , Zergenyi J. 
Published: December 2004

AbstractThe mechanism of the BECKMANN rearrangement and the fragmentation of ketoximes 1 has been studied by determining rate constants and products in «80%» ethanol of several anti‐alkyl‐, ‐cycloalkyl‐, ‐aralkyl‐ and ‐phenyl‐ketoxime tosylates with stationary syn‐methyl and ‐phenyl substituents. The ratio of fragmentation to amide formation is not related to reaction rate, but increases with the stability of the carbonium ion R+ formed, as reflected by the solvolysis rates of the corresponding alkyl chlorides RC1. Fragmentation to nitriles, therefore, occurs after the rate‐deter‐ mining migration step.
Recherches sur les arǒmes 10ecommunication [1] Sur l'arǒme des fraises fraîches. Analyse des composés, esters et alcools volatils
Authors: Winter M. , Willhalm B. 
Published: December 2004

AbstractThe analysis of the volatile parts of fresh strawberry flavour is described. Among 35 substances identified, the following had not been found before in strawberries:

Carbonyl compounds: propanal, acrolein, crotonal, pent‐2‐enal, cis‐hex‐3‐enal, pentan‐2‐one, and heptan‐2‐one.
Alcohols: pent‐1‐en‐3‐ol, heptan‐2‐ol and benzylic alcohol.
Esters: propyl acetate, methyl caproate, hexyl butyrate, isopropyl butyrate, ethyl crotonate and trans‐hex‐2‐en‐1‐yl butyrate.
Scillarenin‐β‐D‐glucosid, ein neues Herzglykosid aus der roten Meerzwiebel 52. Mitteilung über Herzglykoside [1]
Authors: von Wartburg Albert 
Published: December 2004

AbstractThe isolation of scillarenin‐@‐D‐glucoside, a hitherto unknown glycoside from the red variety of squill (sea onion, Scilla maritima (BAKER) L.), is described. The structure of the new compound has been elucidated by acid hydrolysis to D‐glucose and the anhydrogenin scillaridin (VII), and by enzymatic degradation to the true aglycone scillarenin (VIII).
Ein neues Diterpen aus Salvia officinalis L. und eine Notiz zur Konstitution von Pikrosalvin
Authors: Linde Horst 
Published: December 2004

AbstractAus den Blättern von Salvia officinalis L. konnte eine neue Diterpen‐diphenol‐carbonsäure (äls Diacetylverbindung) isoliert und in ihrer Konstitution aufgeklärt werden. Durch eine relativ einfache und übersichtlich verlaufende Reaktionsfolge liess sich eine Verknüpfung rnit dem in derselben Pflanzenart von BRIESKORN et al. aufgefundenen Pikrosalvin erzielen, womit die von diesen Autoren postulierte Konstitution XIII (vgl. [6]) für Pikrosalvin im Sinne der Formel XIV modifiziert werden sollte. Pikrosalvin selbst liess sich in dem untersuchten Drogenmuster nicht auffinden.
Über die Synthese des 1,2,4‐Triacetylbenzols
Authors: Hopff H. , Grasshoff J. 
Published: December 2004

AbstractThe unknown 1,2,4‐triacetylbenzene has been prepared by oxidation of 2,4‐di‐ethylacetophenone with aqueous potassium permanganate. With amino acids in low concentrations, it gives deeply coloured solutions.
In den Catecholamin‐Metabolismus eingreifende Substanzen. 3. 2,3‐Dihydroxyphenylacetamide und verwandte Verbindungen
Authors: Carlsson A. , Corrodi H. 
Published: December 2004

AbstractA series of new derivatives of 2,3‐dihydroxyphenylacetamide and congeners is described. Results are reported which support the view that these compounds inhibit in mammals the enzymatic hydroxylation of phenylalanine to tyrosine, of tryptophan to 5‐hydroxytryptophan, and of tyrosine to dopa, without inhibiting catechol‐O‐methyl‐transferase (COMT). In this regard they differ from the earlier published 3,4‐dihydroxyphenylacetamides (dopacetamides) Most potent are α‐ethoxy‐2,3‐dihydroxyphenylacetamide and α‐isopropyl‐2,3‐dihydroxyphenylacetamide.