bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impacts of climate change on streamflow of Qinglong River, China
Authors: Liu Xingpo , Tang Zixuan 
Published: December 2023

Abstract

Climate change significantly influences water resources and flood hazards in global watersheds. This study focuses on predicting the impact of climate change on the streamflow of the Qinglong River situated in northern China. The streamflow of the Qinglong River (2021-2100) under two climate change scenarios (RCP 4.5 and RCP 8.5) was mainly synthesized over multiple timescales. Meteorological data from 31 Global Climate Models (GCMs) in the Coupled Model Intercomparison Project Phase 5 (CMIP5) served as inputs for the Hydrological Simulation Program-Fortran (HSPF) to conduct hydrological simulations. Results show that: (1) The peak flood flow and average daily streamflow for the RCP4.5 scenario are at least 101.15% and 110.14% of the historical phase, and at least 108.89% and 121.88% of the historical phase for the RCP8.5 scenario. (2) Under both scenarios, the proportion of summer streamflow to the annual total is expected to increase from 61.46% (historical phase) to over 85%, while the proportion of winter streamflow to the annual total is expected to decrease from 8.84% (historical phase) to below 0.5%. (3) Compared to the historical period, the maximum increase in future multi-year average annual streamflow for the RCP4.5 and RCP8.5 scenarios is 30.34%, 31.48%, respectively.
Review on different shapes of spurs and their effects on channel morphology
Authors: Chakravarty Supran , Patel Harish Kumar , Mohanty Bijayananda , Kumar Bimlesh 
Published: December 2023

Abstract

In this paper, the significance of the shape of spurs on flow and bed morphology is understood, accompanied by an appeal to investigate alternative shapes like L-head, T-head spurs, and hockey-shaped spurs, which could offer considerable benefits for river management. The spurs with T-head shape are found to be more efficient in reducing the bed scouring of the channel relatively, although it depends on the orientation of the spur, location of installation, and shape of the channel. Furthermore, development of horseshoe vortex is found insignificant near the base of the T-head spur dike. T-head spurs could more effectively redirect flow and prevent erosion while L-head spurs may enhance riverbank stability. This highlights the need for more investigation into how different spur shapes collectively affect river morphology, flow velocity, and sediment transport patterns. Temporal variations in bed morphology, especially the scour depth and sediment transport dynamics near spur dikes, should also be investigated to understand their changing impact better. Finally, this study provides a complete summary of existing knowledge gaps and future research initiatives relevant to various shapes of spur dikes and their role in riverbank erosion management.
Potential Therapeutic Role of Cannabinoid System in Alzheimer’s Disease: A Review
Authors: Zargar Abrar Ahmad , Kumar Ranjeet , Kumar Arvind , Gangwar Ruby , Sharma Amit 
Published: December 2023

Abstract:The purpose of the study was to investigate the role of the endocannabinoid system and the therapeutic potential benefits of cannabinoids in Alzheimer’s disease. The most frequent form of dementia in older individuals is Alzheimer's disease (AD), a progressive neurological ailment that gradually deprives people of their memory, cognitive abilities, and, ultimately, their ability to perform daily tasks. Alzheimer's disease is distinguished by a progressive deterioration in cognitive function, which includes a decline in memory, learning capacity, and thinking power. The human body's endocannabinoid system functions as a channel for cell communication. It is a neurotransmission system that is present in various regions of the body and tissues as well as assists in the control of a number of metabolic processes. Endocannabinoids, enzymes, and cannabinoid receptors all play a role in managing a variety of biological functions. In this review, we aimed to summarize the endocannabinoid system, the effect of beta-amyloid, tau-protein accumulation and neuroinflammation, potential therapeutic benefits of cannabinoids, current pre-clinical and clinical evidence for the potential therapeutic benefits, limitations, and challenges, and potential future research in the field. Emerging scientific data suggests that the ECS (Endocannabinoid system) is linked to neurodegenerative illnesses and that altering its tone may be a useful therapeutic strategy for the treatment of AD (Alzheimer’s disease).
Cultivating Bone Health: Exploring Medicinal Plants and Bioactive Compounds for Osteoporosis Treatment
Authors: Dhiman Simran , Chopra Bhawna , Dhingra Ashwani K , Grewal Ajmer Singh , Kriplani Priyanka , Deswal Geeta , Dass Rameshwar , Guarve Kumar 
Published: December 2023

Background:Osteoporosis is a severe bone condition characterized by a bone mineral density (BMD) 2.5 standard deviations below peak bone mass. Osteoporosis will become a serious issue as the population ages. Traditional anti-osteoporotic medications are effective in both the prevention and treatment of Osteoporosis. However, they are linked to several adverse effects, enabling many women to seek alternative treatment with medicinal herbs. Chinese herbs, which are all-natural products, are thought to treat Osteoporosis primarily by improving bone quality.Methods:A literature survey has been carried out to determine the real potential of medicinal plants and their bioactive constituents in treating Osteoporosis.Results:Many medicinal plants can modulate bone metabolism and thus reduce bone loss. TCM formulations and their constituent plant remedies have a wealth of phytochemicals with significant promise for discovering novel antiosteoporotic medications. The active substances in TCM formulae can be established as potency medications in combination with antiosteoporotic benefits that may be superior to those of the individual compounds.Conclusion:The primary goal of the review is to describe the potential of antiosteoporosis medicinal plants and some of their phytoconstituents, along with an overview of osteoporosis pathogenesis, clinical studies, and their patent studies.
The Amalgamation of Federated Learning and Explainable Artificial
Intelligence for the Internet of Medical Things: A Review
Authors: Govardanan Chemmalar Selvi , Murugan Ramalingam , Yenduri Gokul , Gurrammagari Deepti Raj , Bhulakshmi Dasari , Kandati Dasaradharami Reddy , Supriya Yarradoddi , Gadekallu Thippa Reddy , Rathore Rajkumar Singh , Jhaveri Rutvij H 
Published: December 2023

Abstract:
The Internet of Medical Things (IoMT) has emerged as a paradigm shift in healthcare,
integrating the Internet of Things (IoT) with medical devices, sensors, and healthcare systems.
From peripheral devices that monitor vital signs to remote patient monitoring systems and smart
hospitals, IoMT provides a vast array of applications that empower healthcare professionals. However, the integration of IoMT presents numerous obstacles, such as data security, privacy concerns,
interoperability, scalability, and ethical considerations. For the successful integration and deployment of IoMT, addressing these obstacles is essential. Federated Learning (FL) permits collaborative model training while maintaining data privacy in distributed environments like IoMT. By incorporating Explainable Artificial Intelligence (XAI) techniques, the resulting models become
more interpretable and transparent, enabling healthcare professionals to comprehend the underlying
decision-making processes. This integration not only improves the credibility of Artificial Intelligence models but also facilitates the detection of biases, errors, and peculiar patterns in the data.
The combination of FL and XAI contributes to the development of more privacy-preserving, trustworthy, and explainable AI systems, which are essential for the development of dependable and
ethically sound IoMT applications. Hence, the aim of this paper is to conduct a literature review on
the amalgamation of FL and XAI for IoMT.
<i>In Silico</i> Analysis of <i>Phalaenopsis Orchid Homeobox1</i> (<i>POH1</i>) Functional Gene for Shoot Development in <i>Phalaenopsis</i> Orchid
Authors: Rasjid Nuzlan , Kurniawan Febri Yuda , Putri Saifa Usni , Linggabuwana Aviesta , Prasojo Ireneus Seno , Semiarti Endang 
Published: December 2023

The most favorite ornamental crop in Indonesia is orchid which benefited as floriculture. Therefore, the quality of this crop must be improved. Biotechnology is appropriate to be used to improve the quality and quantity of orchid plants. To conduct this method, researchers must know what genes function in plant development. In Phalaenopsis orchids, the gene has been identified as homeobox genes called Phalaenopsis Orchid Homeobox1 (POH1). This research aims to conduct in silico analysis of the gene. The materials were retrieved from mRNA and amino acid databases. Then, the materials are aligned, visualized, motif location analysis, motif function discovery, phylogenetic construction, and protein 3D structural modelling. Based on mRNA and amino acid alignment, there are 4 domain regions that are conserved in POH1 and other homologous genes, such as KNOX1, KNOX2, ELK Domain, and Homeobox KN Domain, which roles as a transcription factor involved in plant development. SWISS-MODEL and ColabFold were used in protein modelling of the protein. By ColabbFold modelling, the modelling prediction uses 325 residues, higher than SWISS-MODEL in 59 residues. ColabFold validation by Ramachandra Plot depicts having the most favourite regions is 68.6%, while SWISS-MODEL is 92.3%. Another validation parameter is overall quality factor and QMEAN Score. Protein modelling by ColabFold has overall quality factor 89.252 and QMEAN Score 0.41 ± 0.05. However, SWISS-MODEL 3D prediction has overall quality factor 98.039 and QMEAN score of 0.71 ± 0.11.
DETEKSI AWAL KAKI DATAR PADA PELAJAR SMP DI KOTA JAMBI
Authors: Humaryanto Humaryanto , Patrick Patrick 
Published: December 2023

ABSTRACT
Flat feet (pes planus) are common in infants and children and often disappear before adulthood. Thus, flat feet are described as physiological because they are usually flexible, painless, and have no functional consequences. In rare cases, flat feet can become painful or stiff, which may be a sign of underlying foot pathology, including arthritis or tarsal coalitions. The earlier it is detected, the easier it is to make corrections, the faster the recovery of muscle and bone function, and the better the growth and development of a child. Efforts to screen flat feet in children can be done ink to assess the prints of the subject's feet.
This activity is carried out by using counseling methods and examining the prints of the children's feet. The location of the activity was carried out in 8 randomly selected junior high schools in the city of Jambi. The total number of students suspected of having flat feet was 765 people with a prevalence of 17.99%. Students suspected of having flat feet were 374 women (48.89%), and 433 men (51.11%), ranging in age from 12 to 15 years with an average age of 14 years. All students suspected of flat feet will be subjected to further examination to confirm and measure the severity of flat feet.
Keywords: Counseling, Flat feet, SMP
ABSTRAK
Kaki datar (pes planus) sering terjadi pada bayi dan anak-anak dan sering menghilang sebelum menginjak dewasa. Dengan demikian, kaki datar digambarkan sebagai fisiologis karena biasanya fleksibel, tidak nyeri, dan tidak memiliki konsekuensi fungsional. Dalam kasus yang jarang terjadi, kaki datar dapat menjadi menyakitkan atau kaku, yang mungkin merupakan tanda patologi kaki yang mendasarinya, termasuk radang sendi atau koalisi tarsal. Semakin dini terdeteksi, semakin mudah koreksi yang dilakukan, semakin cepat pemulihan fungsi otot dan tulang, serta semakin baik tumbuh kembangnya seorang anak. Upaya skrining kaki datar pada anak-anak dapat dilakukan tinta untuk menilai cetakan telapak kaki subjek.
Kegiatan ini dilakukan dengan metode penyuluhan dan pemeriksaan cetakan telapak kaki anak. Lokasi kegiatan dilakukan di 8 SMP yang dipilih secara acak di kota Jambi. Jumlah total siswa yang dicurigai memiliki kaki datar sebanyak 765 orang dengan prevalensi sebesar 17,99%. Siswa yang diduga kaki datar berjenis kelamin perempuan sebanyak 374 orang (48,89%), dan laki-laki 433 orang (51,11%), rentang usia 12 sampai 15 tahun dengan rerata usia 14 tahun. Semua siswa yang dicurigai kaki datar akan dilakukan pemeriksaan lebih lanjut untuk memastikan dan mengukur derajat keparahan dari kaki datar.
Kata Kunci: Penyuluhan, Kaki datar, SMP.
PENINGKATAN PENGETAHUAN SISWA PONDOK PESANTREN NURUL IMAN TENTANG INFEKSI STAPHYLOCOCCUS AUREUS DI KULIT DENGAN METODE PENYULUHAN
Authors: Hanina Hanina , Humaryanto Humaryanto , Gading Patrick William , Aurora Wahyu Indah Dewi , Harahap Huntari 
Published: December 2023

Bakteri Staphylococcus aureus merupakan salah satu bakteri patogen pada manusia yang terdapat pada permukaan kulit maupun hidung manusia. Jika lapisan permukaan tubuh tersebut mengalami luka akibat gesekan, goresan atau penyakit kulit lainnya, bakteri akan menginfeksi bahkan dapat masuk ke pembuluh darah dan menyebabkan bacteremia dan menginfeksi berbagai organ tubuh manusia. Pada kulit, infeksi S.aureus dapat berupa bisul, selulitis, impetigo yang tidak sembuh-sembuh dengan pengobatan antibiotika topical yang umum digunakan. Penularan bakteri ini dapat terjadi melalui luka dan kontak langsung ataupun tidak langsung, misalnya melalui handuk, pakaian atau peralatan olahraga yang digunakan bersama. Hal ini tentu merupakan hal yang biasa terjadi pada sekolah berasrama dimana sekelompok pelajar tinggal pada kamar yang sama dan berbagi peralatan yang sama. Risiko penularan bakteri S.aureus semakin meningkat pada sekolah berasrama.
Penyuluhan ini mengikutsertakan 141 orang responden yang merupakan siswa Pondok Pesantren Nurul Iman Kota Jambi tingkat Madrasah Tsanawiyah. Metode penyuluhan yang dilakukan adalah diskusi interaktif dan pemberian leaflet. Responden mengisi kueisioner sebelum dan sesudah penyuluhan. Hasilnya terdapat peningkatan rata-rata hasil kueisioner dari 50 menjadi 66. Kategori tingkat pengetahuan responden sebelum penyuluhan didominasi oleh kategori cukup. Sedangkan setalh penyuluhan kategori tingkat pengetahuan responden berubah didominasi oleh kategori baik. Hasil analisis chi-square menunjukkkan terdapat perbedaan bermakna tingkat pengetahuan responden sebelum dan sesudah penyuluhan. Dapat disimpulkan bahwa metode penyuluhan dengan diskusi interaktif dan leaflet cukup efektif untuk meningkatkan pengetahuan siswa MTs Nurul Iman mengenai infeksi Staphylococcus aureus pada kulit.
Ubuntu as a valued capability for university students in South Africa
Authors: Mathebula Mikateko , Martinez-Vargas Carmen 
Published: December 2023

Universities are often described as institutions that can promote the wellbeing of their local populations. This is because they are central for advancing human development aims which support the aspirations of students and the communities from which they come. Nevertheless, we know this potential can be constrained by historical processes of oppression and negation of indigenous ways of being and doing. Applying the Capabilities Approach and Human Development paradigm as a normative framework for the outcomes of university education in the South African context, we argue for a focus on the centrality of capabilities (real freedoms) in assessing how well universities are doing to support student wellbeing. We pay special attention to one capability which we see as architectonic for other freedoms, which is Ubuntu. While Ubuntu is generally understood as a moral philosophy, in this paper we articulate it as a valued capability in the space of higher education. We also argue that it is a capability that has transformative and decolonial potential that can enable universities to promote student wellbeing if the conditions to practice it are in place.
Drawing from data collected through qualitative and participatory approaches in two longitudinal research projects that were carried out between 2016 and 2021 with undergraduate students in diverse universities in South Africa, we show that Ubuntu informs students’ conceptions of humanity and their aspirations for ‘a good life’ and that it can inform the vision of transformed and decolonised university spaces that reflect indigenous ways of being and indigenous ways of seeing the world.
Brain magnetic resonance imaging and computed tomography findings in cats and dogs with central nervous system cryptococcosis in Australia: 23 cases (2009–2020)
Authors: Jacobson Else , Podadera Juan , Siow Jia Wen , Woerde Dennis J. , Thompson Mary F. , Tebb Anna , Valle Zoe della , Collins David , Malik Richard 
Published: December 2023

Abstract

OBJECTIVE
To describe the imaging findings in Australian cats and dogs with CNS cryptococcosis.

ANIMALS
23 cases (10 cats; 13 dogs) with CNS cryptococcosis and brain MRI or CT studies available to review.

METHODS
Retrospective, multi-institutional case series. Brain MRI or CT studies were reviewed by a board-certified radiologist. Imaging findings were described and the differences between cats and dogs explored.

RESULTS
Morphologic features were consistent with extra-axial lesions in all (n = 13) dogs and either intra-axial (5/10) or extra-axial (4/10) lesions in cats, with 1 cat having no detectable lesions in low-field brain MRI scans. Meningeal abnormalities were most common, followed by forebrain and cerebellar lesions. Intracranial MRI lesions were typically T2 hyperintense and T1 hypo- to isointense. Four cases had T2 hypointense lesions affecting the brain, sinonasal cavity, or regional lymph nodes. Intracranial CT lesions were mostly soft tissue attenuating. Contrast enhancement was present in all cases with contrast series available, with ring enhancement shown only in cats. Osteolysis was more common in dogs than cats, particularly affecting the cribriform plate. All 13 dogs and many (6/10) cats had at least 1 lesion affecting sinonasal or contiguous tissues, and locoregional lymphadenomegaly was common (7/10 cats; 11/13 dogs).

CLINICAL RELEVANCE
Imaging lesions in cryptococcal meningoencephalitis were extra-axial in dogs but could be intra-axial or extra-axial in cats. Careful examination for extracranial lesions (sinonasal, retrobulbar, facial soft tissue, tympanic bullae, or locoregional lymph nodes) is important to provide alternative safe biopsy sites. T2 hypointense lesions, while rare, should prompt consideration of cryptococcosis.
Seroprevalence of Schmallenberg Virus in Sheep in Belgrade Epizootic Area
Authors: Veljović Ljubiša , Maksimović Zorić Jelena , Glišić Dimitrije , Nišavić Jakov , Maletić Jelena , Milićević Vesna 
Published: December 2023

Abstract
Schmallenberg disease is an infectious disease of cattle, sheep, and goats of viral aetiology caused by the Schmallenberg virus that belongs to the family Bunyaviridae and the genus Ortobunyavirus. Schmallenberg disease is a vector-borne disease transmitted by midges from the genus Culicoides but also by other hematophagous insects. The disease has a seasonal character and most often occurs in the warm months, from late spring to autumn. In this study, we investigated the seroprevalence of Schmallenberg disease in sheep in the epizootic area of Belgrade in the period from 2017 to 2022. A total of 600 sheep serums from the serum bank were tested, 100 serum samples from each year. Sera were tested by commercial ELISA test for the detection of specific antibodies against the Schmallenberg virus. The results showed an average annual seroprevalence of 24.5% in sheep in the Belgrade area in these six years with an increasing trend predicted for the next years.
Clearance of Trehalose Lyophilized Platelets in Mice
Authors: Kim Mu-Young , Han Hyun-Jung 
Published: December 2023

Abstract
The utilization of stored platelet transfusion has emerged as an effective approach in the management of thrombocytopenia. However, the limited availability of fresh platelets in veterinary medicine due to the challenging storage requirements poses a significant constraint. Lyophilized platelets offer extended shelf-life and convenient storage options, enhancing their accessibility for thrombocytopenic patients. However, only a limited number of studies have examined the clearance and survival rate of transfused lyophilized platelets, particularly regarding the lyophilization technique utilizing trehalose as a platelet stabilization agent. The objective of this study was to assess the recovery and survival rate of trehalose lyophilized platelets within the circulatory system. To investigate these parameters, CMFDA-labeled lyophilized platelets were administered to mice, and their recovery and survival rates were analyzed. Flow cytometric analysis revealed the rapid clearance of lyophilized platelets from the systemic circulation. The immediate post-infusion percent recovery of labeled platelet particles was 42.7 ± 8.15 %. The average survival rates at post-infusion time points at 15, 30, 45, and 60 minutes were 28.2 ± 4.31, 14.5 ± 3.56, 5.1 ± 2.02, and 0.82 ± 0.57, respectively. The calculated mean half-life was 8.39 ± 0.44 minutes. The most pronounced decrease in labeled lyophilized platelet count occurred during the 30-minute timeframe immediately following infusion. Subsequently, over 99% of lyophilized platelets were eliminated after 60 minutes post-infusion. These findings indicate that higher dosages and more frequent administration of trehalose lyophilized platelets might be necessary to achieve a therapeutic effect comparable to that of fresh platelets.
Mathematics Connection Between CMM and CNC Parameter Setup
Authors: Serban Petru Emanoil , Stanase Iulian , Peti Ferencz 
Published: December 2023

Abstract
The purpose of this article is to establish a new approach for the use of CMM in production serial validation. Even the scope of CMM’s is to give results based on drawing requirements, the capability of this measurement system, can ensure with an advanced program development the parameter setup of CNC’s during setup or any changeover stages. The preparation and the scope of this development is to analyze the mathematic approach of coordinate systems which must be converted from a static coordinate system to a new system that is changed at every CNC clamping operation and rotation of any axis.
Assessment on the Acoustic Comfort Inside the Heavy Vehicle Cabin
Authors: Căşeriu Bianca , Blaga Petruța 
Published: December 2023

Abstract
Noise, vibration, and harshness (NVH) researchers spend inexhaustible resources of materials, time and money in determining the objective factors that are important in ensuring acoustic comfort in vehicles. In this paper, the factors that directly influence the interior acoustic pressure level in a heavy-duty vehicle were investigated. It was determined using specific descriptors and different units of measurement in assessment of sound levels and the impact generated by noise, the level of interior acoustic pressure and particular values of some prominent sources of noise in the operation of vehicles (engine, HVAC system), taking into account the factors of insurance and thermal comfort, with the aim of determining the cumulative impact at the board of heavy vehicles due to noise.