bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sensory acceptability of sweet potatoes: Influence of the cultivar, cooking method and the city
Authors: Sosa M. , Garitta L. , Elizagoyen E. , Arce S. , Budde C. , Gabilondo J. , Ottaviano F. Gugole 
Published: November 2023

AbstractBackgroundThis study aimed to evaluate the sensory acceptability of four sweet potato cultivars (Beauregard, Morada‐INTA, Colorado‐INTA, and Arapey), considering two cooking methods: boiled and baked; and two cities, 9 de Julio (9DJ) and San Pedro (SP), of Buenos Aires province. 120 women were recruited in each city. A home use test was carried out. Each consumer received at home each sample in a bag containing three sweet potatoes and the evaluation form. The sensory acceptability of different characteristics of the samples was evaluated, before and after cooking. To inquire the reasons for consumption of each sample, the methodology check all that apply (CATA) was used.ResultsOf the two factors evaluated (city and cooking method), city had a significant influence when evaluating the samples. Participants of SP gave higher acceptability to Beauregard cultivar than 9DJ in most attributes. Colorado INTA had greater acceptability in some descriptors by the consumers of 9DJ. While Arapey and Morada INTA had the greatest acceptability in 9DJ trial. In CATA results 9DJ consumers associated the Beauregard cultivar with negative phrases: It tastes weird and It has little flavor/tasteless and to a lesser extent to The internal color is artificial and It breaks when cooking. While SP consumers characterized with negative phrases the Arapey and Morada INTA samples as follows: It changes color (brown) quickly, Its shape is not regular and When cooked, it has threads or fibers.ConclusionConsumer preferences provide opportunities for the development or improvement of new cultivars. It would be interesting to extend this study to other regions and/or countries.
Effects of co‐fermentation of high‐yield ester Zygosaccharomyces rouxii and Saccharomyces cerevisiae on the quality of rice wine
Authors: Cui Rongrong , Liu Xueli , Wang Qifeng , Wang Shujia , He Jing , Zhou Shengli , Zhao Guozhong , Yao Yunping 
Published: November 2023

AbstractBackgroundAt present, rice wine has the characteristics of fast fermentation, energy saving, and simple production due to the addition of commercial Saccharomyces cerevisiae. However, this kind of fermented rice wine has the disadvantages of single flavor and weak taste. To address this concern, the combination of Saccharomyces cerevisiae and non‐Saccharomyces yeast has been identified as an effective approach to enhance the quality of fermented rice wine. This research aims to further enhance the ethyl ester and higher alcohol components of rice wine by utilizing the co‐fermentation method of high‐yield ester Zygosaccharomyces rouxii and Saccharomyces cerevisiae, thereby increasing the aroma complexity of rice wine.ResultsAccording to the fermentation performance and gas chromatography–mass spectrometry (GC–MS) analysis, it was found that S. cerevisiae GJM and Z. rouxii SC01 have a strong metabolic ability for glucose and sucrose. Furthermore, the crucial alcohols such as isobutanol, isoamyl alcohol, and phenylethyl alcohol increased by 85%, 29%, and 138%, respectively, when compared to single S. cerevisiae GJM. Additionally, the ethyl acetate and phenylethylene acetate were increased by 1.35 and 1.45 times, respectively, when compared to single S. cerevisiae GJM. These findings were comparable with the results of sensory evaluation and electronic nose analysis, where the fruit flavor score and the content of mellow substances were found to be higher.ConclusionThese findings suggest that the co‐fermentation of S. cerevisiae and high‐yield ester Z. rouxii has the potential to enhance the quality and diversity of aroma in liquid rice wine.
Preparation and Specific Detection of Zn2+ Ions of Polyacylhydrazones with Polymerization‐Induced Emission
Authors: Guo Huiying , Huang Yu , Lin Jiayu , Hao Tingting , Zhang Pengfei , Zhao Ronghui , Cao Lili , Deng Kuilin 
Published: November 2023

AbstractHerein, inspired by the specific detection of the commercial dithizone to Zn2+, a series of polyacylhydrazones (PAHZs) with polymerization‐induced emission (PIE) properties are successfully prepared and applied to the specific recognition and detection of Zn2+. It is found that all selected monomers do not emit fluorescence. In contrast, the as‐prepared PAHZs can emit strong fluorescence at 455 nm, due to the intramolecular aggregation of acylhydrazone groups along the macromolecular chains, indicating a significant PIE effect. As it is expected, the PAHZs can specifically recognize and detect Zn2+ ions from 17 metal ions by the significantly enhanced fluorescence with a lower limit of detection (LOD) of 66 nM. Additionally, the complexation ratio of 2:1 between the repeating units in PAHZs and Zn2+, the coordination of Zn2+ with N and O atoms on acylhydrazone groups, and the fluorescence enhancement induced via intramolecular proton transfer are confirmed by 1H NMR and FT‐IR measurements. In conclusion, the successful preparation of PIE‐active PAHZs and the specific detection of Zn2+ ions provide a useful reference for the molecular design of new functional materials on the base of the traditional detection methods.
Well‐posedness of degenerate fractional differential equations with finite delay in complex Banach spaces
Authors: Bu Shangquan , Cai Gang 
Published: November 2023

AbstractWe study the well‐posedness of the degenerate fractional differential equations with finite delay: on Lebesgue–Bochner spaces and periodic Besov spaces , where and are closed linear operators in a complex Banach space satisfying , and are fixed, when , and the delay operator is a bounded linear operator from (resp. ) into . Using known operator‐valued Fourier multiplier theorems on and , we completely characterize the ‐well‐posedness and the ‐well‐posedness of above equations. We also give concrete examples that our abstract results may be applied.
Functional analysis of a novel splice site variant in the ASAH1 gene
Authors: Yan Shujuan , Fu Fang , Zhou Hang , Huang Ruibin , Wang You , Liao Can 
Published: November 2023

AbstractBackgroundAcid ceramidase (ACDase) deficiency is an ultrarare autosomal recessive lysosomal disorder caused by pathogenic N‐acylsphingosine amidohydrolase (ASAH1) variants. It presents with either Farber disease (FD) or spinal muscular atrophy with progressive myoclonic epilepsy (SMA‐PME).ObjectiveThe study aims to identify a novel splice site variant in a hydrops fetus that causes ASAH1‐related disorder, aid genetic counseling, and accurate prenatal diagnosis.MethodsWe report a case of hydrops fetalis with a novel homozygous mutation in ASAH1 inherited from non‐consanguineous parents. We performed copy number variation sequencing (CNV‐Seq) and whole exome sequencing (WES) on the fetus and family, respectively. Minigene splicing analyses were conducted to confirm the pathogenic variants.ResultsWES data revealed a splice site variant of the ASAH1 (c.458‐2A>T), which was predicted to affect RNA splicing. Minigene splicing analyses found that the c.458‐2A>T variant abolished the canonical splicing of intron 6, thereby activating two cryptic splicing products (c.456_458ins56bp and c.458_503del).ConclusionsOverall, we identified a novel splice site variant in the mutational spectrum of ASAH1 and its aberrant effect on splicing. These findings highlight the importance of ultrasonic manifestation and family history of fetal hydrops during ASAH1‐related disorders and could also aid genetic counseling and accurate prenatal diagnosis. To the best of our knowledge, this is the shortest‐lived account of ASAH1‐related disorders in utero with severe hydrops fetalis.
Clinical study and genetic analysis of Cornelia de Lange syndrome caused by a novel MAU2 gene variant in a Chinese boy
Authors: Peng Yin , Zhu Ying , Wu Lin , Deng Fang 
Published: November 2023

AbstractBackgroundCornelia de Lange syndrome (CdLS) is mainly characterized by specific facial features, growth retardation, and bone deformities. Seven genes reportedly cause CdLS. Recent research has reported that loss‐of‐function variants affecting MAU2, which encodes a regulator of the cohesin complex, can cause CdLS. Thus far, only one MAU2‐CdLS case has been reported worldwide.MethodsWe detected a novel variant in MAU2 gene, NM_015329, c.526C>T (p.Arg176Trp) in a Chinese patient with CdLS, constructed a plasmid for in vitro transcriptional and protein level analysis, and analyzed the interaction between the MAU2/NIPBL complex using molecular dynamics (MD).ResultsThe results showed that the level of the exogenous MAU2 mutant protein was significantly reduced compared with that of the exogenous wild‐type protein. However, MD analysis predicted an increased binding free energy between the MAU2 and NIPBL proteins that may impact the structural stability of the complex.ConclusionWe investigated a MAU2‐CdLS case in a Chinese family, which strengthens the association between MAU2 variants and CdLS phenotypes. We therefore propose that MAU2 be included in the CdLS gene screening list.
X‐band dual‐band horn antenna with isoflux pattern for deep‐space applications
Authors: Liu Zhijia , Lu Fan , Duan Jiangnian , Jiang Hua , Sun Dayuan , Yang Dong , Fan Yong , Huang Yuhan 
Published: November 2023

AbstractIn this paper, an X‐band dual‐band dual‐polarized medium‐gain antenna (MGA) is designed for deep‐space satellite applications. The MGA has isoflux radiation patterns in the 7.145–7.19 and 8.40–8.45 GHz frequency bands. The concentric ring horn qualification model named MGA is developed for TIAN WEN‐2 (TW‐2) mission. MGA is fabricated and the measurements are conducted on it and its installation on the deck of the TW‐2 Radiation Mockup (RM). The performance evaluation of MGA and its corresponding RM measurements indicate an axial ratio lower than 4.0 dB and a gain higher than 5.8 dBic on the operational bandwidth at the coverage limit of 40° for all azimuth angles (φ). The calculated and measured data align exceedingly well, confirming that MGA satisfactorily meets the requirements for the forthcoming TW‐2 deep‐space spacecraft.
Stress analysis of elliptical tunnels in an orthogonally anisotropic elastic full‐space under non‐uniform in‐situ stress
Authors: Ai Zhi Yong , Ye Zi Kun , Huang Hong Wei , Hu Ke Xin 
Published: November 2023

AbstractNon‐uniformly distributed in‐situ stress around the tunnel is a significant factor inducing various geohazards during tunnel excavation in the rock mass, and the anisotropy of the rock mass would further differentiate the in‐situ stress state around the tunnel. To ensure the safety of tunnel construction and operation, it is necessary to deeply analyze the stress distribution law and mechanical mechanism of the orthogonally anisotropic elastic media the around tunnel. This paper presents a complex variable function method for the elliptical tunnel in an orthogonally anisotropic elastic full‐space under non‐uniform in‐situ stress. To obtain the analytical solution, the affine transform and conformal mapping are applied to consider the orthogonal anisotropy of material and the ellipticity of the tunnel. A numerical series fitting method is introduced to describe the non‐uniformly distributed load, and then the stress solution around tunnel is further obtained. The comparisons with the existing literature, numerical solutions and model tests are provided to verify the correctness of the proposed method. Finally, the convergence study and the numerical analysis on the stress distribution are given graphically.
Fluid intake behavior in women with refractory overactive bladder undergoing third line therapy
Authors: Zhao Kelley , Harandi Arshia Aalami , Ramgopal Jennifer , Kim Jason , Weissbart Steven 
Published: November 2023

AbstractIntroduction and ObjectivesFluid intake has been shown to be related to urinary symptoms, but no studies to date have investigated the effect of fluid intake on urinary symptoms in women with refractory overactive bladder (OAB). As this group of women are considered to have a possible unique pathophysiologic mechanism of OAB, we investigated the relationship between fluid intake, fluid intake behavior, and urinary symptoms in women with refractory OAB.MethodsA prospective cross‐sectional study of women with refractory OAB was conducted by assessing the relationship between fluid intake and lower urinary tract symptoms (LUTS) in women undergoing third line OAB therapies. Fluid intake and behavior were measured by the questionnaire based voiding diary and urinary symptoms were measured by the International Consultation on Incontinence Questionnaire for Female Lower Urinary Tract Symptoms (ICIQ‐FLUTS). The relationship between fluid intake and symptom severity was assessed using Spearman's rank correlation and χ2 tests.ResultsOf the 126 individuals undergoing third line therapy for OAB, 60 (48%) underwent intradetrusor onabotulinumtoxinA injection (BTX) injection, 42 (33%) peripheral tibial nerve stimulation, and 24 (19%) sacral neuromodulation. The mean total daily fluid intake was 2567.0 ± SD 1292.4 mL and did not differ significantly across treatment groups. Total fluid intake was weakly correlated with worse filling‐type LUTS (r = 0.241, p = 0.007), and there was no relationship between LUTS and caffeinated fluid intake. Half (52%) of the subjects reported current fluid restricting behavior to control urinary symptoms, but this behavior was not correlated with LUTS severity (all p > 0.05). Patients that currently use tobacco have greater LUTS (current = 25.8 ± SD 9.5, former = 14.8 ± SD 6.1, never = 15.0 ± SD 6.1; p < 0.001). BMI was also positively correlated with worse incontinence symptoms (r = 0.351, p < 0.001).ConclusionsFluid intake along with other lifestyle factors, including tobacco use and weight, are minimally related to the symptomatology seen in women with refractory OAB. Further studies are needed to assess if behaviors change during treatment with third line therapies, and if these behavioral changes may affect treatment response.
Functional neuroimaging related to lower urinary tract sensations: Future directions for study designs and selection of patient groups: ICI‐RS 2023
Authors: de Rijk Mathijs M. , Drake Marcus J. , von Gontard Alexander , Solomon Eskinder , Dmochowski Roger , Schurch Brigitte , van Koeveringe Gommert A. 
Published: November 2023

AbstractObjectivesNeuroimaging studies have advanced our understanding of the intricate central nervous system control network governing lower urinary tract (LUT) function, shedding light on mechanisms for urine storage and voiding. However, a lack of consensus in methodological approaches hinders the comparability of results among research groups and limits the translation of this knowledge to clinical applications, emphasizing the need for standardized methodologies and clinical utilization guidelines.MethodsThis paper reports the discussions of a workshop at the 2023 meeting of the International Consultation on Incontinence Research Society, which reviewed uncertainties and research priorities to progress the field of neuroimaging in LUT control and dysfunction.ResultsNeuroimaging holds great potential for improving our understanding of LUT control and pathophysiological conditions. To date, functional neuroimaging techniques have not yet achieved sufficient strength to make a direct clinical impact. Potential approaches that can improve the clinical utilization of neuroimaging were discussed and research questions proposed.ConclusionsNeuroimaging offers a valuable tool for investigating LUT control, but it's essential to acknowledge the potential for oversimplification when interpreting brain activity due to the complex neural processing and filtering of sensory information. Moreover, technical limitations pose challenges in assessing key brain stem and spinal cord centers, particularly in cases of neurological dysfunction, highlighting the need for more reliable imaging of these centers to advance our understanding of LUT function and dysfunction.
Dynamic smooth and stable obstacle avoidance for unmanned aerial vehicle based on collision prediction
Authors: Ma Haixu , Cai Zixuan , Xu Guoan , Yang Guang , Chen Guanyu 
Published: November 2023

AbstractAutonomous dynamic obstacle avoidance of unmanned aerial vehicles (UAVs) based on collision prediction is critical for stable flight missions. UAVs must deal with high‐speed and nonlinearly moving obstacles that obey nonlinear dynamics, which are one of the numerous objects affecting stable flight. To satisfy the requirements of smooth flight and attitude stability, a novel dynamic smooth obstacle avoidance (QVA) method based on obstacle trajectory prediction is proposed. To predict the dynamic obstacle trajectories, a trajectory prediction (QLTP) method using a quasi‐linear parameter varying representations is proposed. The proposed QVA integrates the QLTP approach, velocity obstacle (VO) approach, and artificial potential field (APF) methods. The QVA detects an imminent collision based on the QLTP method, and then replans the UAV path based on the VO method at the time of the predicted collision. The UAV tracks planned waypoints for collision avoidance. To ensure the flight safety of the UAV, a virtual APF is constructed with waypoints as local targets and obstacles. The simulation results show that the proposed method performs better than the improved APF and VO methods in terms of the smoothness of the obstacle avoidance path and the stability of the UAV attitude.
Yinbarnini Ngukunginyi (Singing of Water)
Authors: Dixon Ray Dimakarri , Morgan Terry 
Published: November 2023

ABSTRACTExploratory fracking has commenced in the Beetaloo Basin, adjacent to Mudburra Country. At the time of writing, the Northern Territory Government is preparing to issue production licences to the gas companies involved. Environmental groups and some Aboriginal traditional owners, however, are insisting that the potential impact on land, water, pastoral operations, and Aboriginal communities has not been properly taken into account. Amongst other things, they point to the existence of stygofauna – tiny creatures that live in the underground water – which, though known to the traditional owners for millennia, are relatively new to western science. (It is likely that a word for stygofauna existed in the Mudburra language, but as far as we know it has not survived.) Research to establish environmental baselines prior to the commencement of fracking indicates that the stygofauna perform a vital function in purifying the underground water, and that they would be seriously threatened by fracking operations. As part of the protest movement against fracking, the authors have composed a song about stygofauna to be taught to the Mudburra children at Newcastle Waters School.
A multicenter, double‐blind, randomized, controlled study of patients with treatment‐resistant schizophrenia treated with yokukansan for 12 weeks
Authors: Horiguchi Jun , Wake Rei , Murotani Kenta , Seno Haruo , Miyaoka Tsuyoshi , Inoue Ken 
Published: November 2023

AbstractAimWe conducted a 12‐week double‐blind, placebo‐controlled, multicenter study to evaluate the efficacy and safety of yokukansan in patients with schizophrenia.MethodsPatients with schizophrenia resistant to antipsychotics whose Positive and Negative Syndrome Scale (PANSS) scores were stable within five points were enrolled and assigned to the yokukansan or placebo group. Fifty‐three of the 61 consenting patients were allocated to the yokukansan (n = 27) and placebo (n = 26) groups.ResultsThe changes in total and positive PANSS scores at 12 weeks were significantly greater in the yokukansan group than in the placebo group. There were no significant changes in other psychiatric symptom rating scores in either group. Adverse reactions were reported in six of 27 patients (22.2%) in the yokukansan group and five of 26 patients (19.2%) in the placebo group, all of which were nonserious.ConclusionYokukansan is very safe and has clinical potential as a treatment for schizophrenia in combination with Western medicine.
The effects of blueberry and cranberry supplementation on blood pressure in patients with cardiovascular diseases: A systematic review and meta‐analysis of randomized clinical trials
Authors: Delpino Felipe Mendes , dos Santos Francine Silva , Flores Thaynã Ramos , Cerqueira Henrique S. , Santos Heitor O. 
Published: November 2023

AbstractBlueberries and cranberries are berry fruits with the highest number of randomized clinical trials (RCTs) focusing on blood pressure (BP). This systematic review and meta‐analysis of RCTs analyzed the effects of blueberry and cranberry supplementation alone and in concert with systolic BP (SBP) and diastolic BP (DBP) in patients with cardiometabolic diseases. The searches were performed until August 2023 in the following databases: PubMed, Scopus, Web of Science, Cochrane, and Embase. Studies that examined the effects of blueberry or cranberry intake/supplementation were included. The risk of bias was evaluated using the Rob 2 scale. A meta‐analysis was performed to estimate the effects of blueberry and cranberry supplementation on BP levels in patients with cardiometabolic diseases. A total of 17 articles were included, from which two found significant results from blueberry and/or cranberry supplementation in reducing BP. Pooled results revealed statistically non‐significant reductions of −0.81 mm Hg for SBP (95% confidence interval [CI]: −2.26, 0.63; I2 = 0%) and −0.15 mm Hg for DBP (95% CI: −1.36, 1.05; I2 = 27%). Blueberry and/or cranberry supplementation had neutral effects on SBP and DBP in patients with cardiometabolic diseases, regardless of duration or age. Further high‐quality studies are needed to firmly establish clinical efficacy.
How does financial openness affect pollution emission of industrial enterprises?—Empirical evidence from the entry of foreign banks in China
Authors: Liu Bei , Bao Xing , Qiu Zhaoxuan , Zhang Yunyun , Xia Qiu 
Published: November 2023

AbstractCurrently, the effects of financial openness (FO) on the environment have not been assessed at the micro level of enterprises. This article uses the difference‐in‐differences method to explore the pollution abatement effect of FO. The results show that FO can effectively promote pollution abatement with a significant environmental performance enhancement effect. In addition, the pollution abatement effect of FO is stronger in large, heavy industrial, and state‐owned enterprises. Besides, FO significantly alleviates financing constraints and promotes the pollution abatement by driving R&D investment and strengthening the intensity of end‐of‐pipe treatment. Policy recommendations are given to steadily expand the FO pattern, improve the financial disclosure system of small and medium‐sized enterprises, and optimize subsidies for increased R&D investment to stimulate pollution abatement. A reference for other emerging economies, especially transitioning economies, is provided to fully utilize the financial system under construction or improvement to realize the value of pollution control.