bluuebunny/crossref_metadata_2025_split huggingface dataset:
Food cravings after bariatric surgery: comparing laparoscopic sleeve gastrectomy and Roux-en-Y gastric bypass
Authors: Koball Afton M. , Ames Gretchen E. , Fitzsimmons Alec J. , Kallies Kara J. , Bennie Barb A. 
Published: January 2024

Abstract
Background
Research suggests that food choices, preferences, and tastes change after bariatric surgery, but evidence regarding changes in food cravings is mixed.

Objectives
The primary aim of this cohort study was to compare food cravings during the first year following bariatric surgery in patients who had undergone sleeve gastrectomy (SG) versus Roux-en-Y gastric bypass (RYGB).

Setting
Integrated multispecialty health system, United States.

Methods
Patients aged ≥ 18 years seen between May 2017 and July 2019, provided informed consent, completed the Food Craving Inventory (FCI), and had ≥ 1 year of follow-up after undergoing primary SG or RYGB were included in the study. Secondary data captured included psychological and behavioral measures. Preoperative and postoperative (3, 6, 9, and 12 months) FCI scores of patients who underwent SG and RYGB were compared.

Results
Some attrition occurred postoperatively (N = 187 at baseline, 141 at 3 months, 108 at 6 months, 89 at 9 months, and 84 at 12 months). No significant relationship between pre- or postoperative food cravings and surgery type was found except on the carbohydrate subscale. Patients with higher preoperative food addiction symptoms were not more likely to experience an earlier reoccurrence of food cravings during the first 12 months after surgery. Likewise, patients with higher levels of preoperative depression and anxiety were not more likely to have early reoccurrence of food cravings during the first 12 months after surgery; however, those with higher PHQ9 scores at baseline had uniformly higher food craving scores at all timepoints (pre-surgery, 3 m, 6 m, 9 m, and 12 m).

Conclusions
Results suggest that food cravings in the year after bariatric surgery are equivalent by surgery type and do not appear to be related to preoperative psychological factors or eating behaviors.

Level of evidence
Level III: Evidence obtained from well-designed cohort.
Design of synthetic peptide-based fluorescence probes for turn-on detection of hyaluronan
Authors: Fan Xinyu , Sato Yusuke , Shiraki Yudai , Nishizawa Seiichi 
Published: January 2024

AbstractHerein, we designed and examined a series of fluorescent peptide-based probes for turn-on detection of hyaluronan (HA), a member of the glycosaminoglycan family. We utilized two kinds of synthetic HA-binding peptides as the binding unit for HA, and each peptide was coupled with three kinds of environment-sensitive fluorophores as the signaling unit. From the examination of the peptides, fluorophores, and the position and number of fluorophore modification, we found that X7 peptide (RYPISRPRKR) labelled with an aggregation-induced emission (AIE) fluorogen, tetraphenylethene (TPE), at the N-terminal (named TPE-X7) did function as a light-up probe for HA. The response of TPE-X7 was highly selective to higher molecular weight HA in comparison with lower ones, having the possible potential for the analysis of HA size. TPE-X7 was also applicable to the quantification of HA in synovial fluids.
Graphical abstract
Overcoming the limitations of wildlife disease monitoring
Authors: Barroso Patricia , López-Olvera Jorge R. , Kiluba wa Kiluba Théophile , Gortázar Christian 
Published: January 2024

AbstractIntegrated wildlife monitoring (IWM) combines infection dynamics and the ecology of wildlife populations, including aspects defining the host community network. Developing and implementing IWM is a worldwide priority that faces major constraints and biases that should be considered and addressed when implementing these systems. We identify eleven main limitations in the establishment of IWM, which could be summarized into funding constraints and lack of harmonization and information exchange. The solutions proposed to overcome these limitations and biases comprise: (i) selecting indicator host species through network analysis, (ii) identifying key pathogens to investigate and monitor, potentially including nonspecific health markers, (iii) improve and standardize harmonized methodologies that can be applied worldwide as well as communication among stakeholders across and within countries, and (iv) the integration of new noninvasive technologies (e.g., camera trapping (CT) and environmental nucleic acid detection) and new tools that are under ongoing research (e.g., artificial intelligence to speed-up CT analyses, microfluidic polymerase chain reaction to overcome sample volume constraints, or filter paper samples to facilitate sample transport). Achieving and optimizing IWM is a must that allows identifying the drivers of epidemics and predicting trends and changes in disease and population dynamics before a pathogen crosses the interspecific barriers.
Phonological and acoustic properties of ATR in the vowel system of Akebu (Kwa)
Authors: Makeeva Nadezhda , Kuznetsova Natalia 
Published: January 2024

AbstractThis study examines phonological and phonetic properties of ATR contrasts in the vowel system of Akebu (Kwa). The sum of descriptive evidence, including vowel harmony, vowel distribution in non-harmonising contexts, vowel reduction and typological and etymological considerations, indicates a rare vowel inventory with an ATR contrast in front/back vowels but a height contrast in the three redundantly [−ATR] central vowels /ᵻ, ə, a/. This analysis was checked against four common acoustic metrics of ATR: F1 and F2 frequencies, spectral slope and F1 bandwidth size (B1). As expected, the results for the last three metrics were variable across speakers and vowel types, and are therefore inconclusive. The results for F1 were consistent but do not distinguish between ATR and vowel height. Two results nonetheless suggest the [−ATR] status of central vowels: they occupy the same belt of F1 frequencies and show the same position of observed-over-predicted B1 values as front and back [−ATR] vowels.
Machine Ethics in Care: Could a Moral Avatar Enhance the Autonomy of Care-Dependent Persons?
Authors: Misselhorn Catrin 
Published: January 2024

AbstractIt is a common view that artificial systems could play an important role in dealing with the shortage of caregivers due to demographic change. One argument to show that this is also in the interest of care-dependent persons is that artificial systems might significantly enhance user autonomy since they might stay longer in their homes. This argument presupposes that the artificial systems in question do not require permanent supervision and control by human caregivers. For this reason, they need the capacity for some degree of moral decision-making and agency to cope with morally relevant situations (artificial morality). Machine ethics provides the theoretical and ethical framework for artificial morality. This article scrutinizes the question how artificial moral agents that enhance user autonomy could look like. It discusses, in particular, the suggestion that they should be designed as moral avatars of their users to enhance user autonomy in a substantial sense.
NONLINEAR SELF-MODULATION OF GRAVITY-CAPILLARY WAVES ON SHEAR CURRENTS IN FINITE DEPTH
Authors: PAL TANMOY , DHAR ASOKE KUMAR 
Published: January 2024

AbstractA nonlinear evolution equation correct to fourth order is developed for gravity-capillary waves on linear shear currents in finite water depth. Therefore, this equation covers both effects of depth uniform currents and uniform vorticity. Starting from this equation, an instability analysis is then made for narrow banded uniform Stokes waves. The notable feature is that our investigation due to fourth order shows a remarkable improvement compared with the third-order one, and produces an excellent result compatible with the exact result of Longuet-Higgins. We observe that linear shear currents considerably change the modulational instability properties of capillary-gravity waves, such as the growth rate and bandwidth of instability.
Comment on “Highly Contrasted Geochemical Pattern in Sediments of the Okavango Delta, Botswana Driven by Dust Supply, Hydrological Heritage and Biogeochemical Reactions” by Jolivet et al.
Authors: McCarthy Terence , Humphries Marc 
Published: January 2024

AbstractThe Okavango Delta in southern Africa has been the subject of geomorphological and hydrological investigations since the 1970s. In the early 1990s, McCarthy and co‐workers developed a geomorphological and hydrological model which describes the processes that give rise to the gently undulating topography and the lack of saline surface water in this semi‐arid environment. This model is based on extensive investigations of soil and water chemistry conducted across the Okavango Delta, and has been subject to rigorous testing by a number of independent researchers. In their recent paper, Jolivet et al. (2023, https://doi.org/10.1029/2023GC010978) proposed an alternative hydrological model based on chemical and mineralogical analyses of samples from six auger holes drilled at a site on the lower fringe of the permanent swamp. We provide a critique of their model and explain how this model cannot describe the geohydrological functioning of the Okavango Delta. Jolivet et al. suggest there are two shallow aquifers, one hosted in sand and the other in clay‐rich material. Previous studies of subsurface soils on 18 islands have failed to reveal a deeper clay‐rich layer. Rather, the shallow groundwater is laterally fully connected and salinity varies in response to evapotranspiration. We attribute REE fractionation in subsurface soils observed by Jolivet et al. to be caused by the precipitation of calcite from groundwater which strongly accumulates REE. We are of the opinion that Jolivet et al. have insufficient data to suggest revisions to the current understanding of the functioning of the Okavango hydrological and sedimentological system.
Evolution of a Lake Margin Recorded in the Sutton Island Member of the Murray Formation, Gale Crater, Mars
Authors: Gwizd S. , Fedo C. , Grotzinger J. , Banham S. , Rivera‐Hernández F. , Gupta S. , Stack K. M. , Edgar L. A. , Vasavada A. R. , Davis J. , Kah L. C. 
Published: January 2024

AbstractThis study uses data from the Mars Science Laboratory Curiosity rover to document the facies of the Sutton Island member of the Murray formation, interpret paleoenvironments, and establish key stratigraphic transitions at Gale crater. Two facies associations were identified: Facies Association 1 (FA1) and Facies Association 2 (FA2). Individual facies in FA1 include planar‐laminated mudstone with minor intervals of planar sandstone, ripple cross‐laminated sandstone, cross‐stratified sandstone, and alternating laminated sandstone and mudstone. Meter‐thick packages of planar‐laminated mudstone in FA1 are interpreted to represent deposition in low‐energy ponded environments along the lake margin. Straight‐ and curve‐crested ripple cross‐laminated facies are interpreted to represent current‐influenced deposition. Cross‐stratified sandstone facies consist of dm‐thick sets that represent deposition in distal channels. Intercalated mm‐scale mudstone and sandstone laminae represent waning flow conditions and possible channel abandonment. Facies in FA1 collectively represent deposition in a distal delta plain. FA2 is comprised of planar‐laminated mudstone with minor sandstone and is interpreted to represent deposition in a lacustrine‐basin setting by suspension settling linked to density flows. FA1 transitions upward into FA2, defining a rapid transgression substantial enough to facilitate the deposition of distal lake facies above delta plain facies. The abrupt transition from FA2 back to FA1 deltaic deposits is suggestive of forced regression. Facies in FA1 and FA2 are consistent with the prevalence of aqueous environments recorded in other Murray formation members and extend our understanding of the dynamic sedimentary processes that characterized ancient lacustrine systems at Gale crater.
Blood donor biobank as a resource in personalised biomedical genetic research
Authors: Clancy Jonna , Ritari Jarmo , Vaittinen Eevaleena , Arvas Mikko , Tammi Silja ,   FinnGen, Koskela Satu , Partanen Jukka 
Published: January 2024

AbstractHealth questionnaires and donation criteria result in accumulation of highly selected individuals in a blood donor population. To understand better the usefulness of a blood donor-based biobank in personalised disease-associated genetic studies, and for possible personalised blood donation policies, we evaluated the occurrence and distributions of common and rare disease-associated genetic variants in Finnish Blood Service Biobank. We analysed among 31,880 blood donors the occurrence and geographical distribution of (i) 53 rare Finnish-enriched disease-associated variants, (ii) mutations assumed to influence blood donation: four Bernard-Soulier syndrome and two hemochromatosis mutations, (iii) type I diabetes risk genotype HLA-DQ2/DQ8. In addition, we analysed the level of consanguinity in Blood Service Biobank. 80.3% of blood donors carried at least one (range 0–9 per donor) of the rare variants, many in homozygous form, as well. Donors carrying multiple rare variants were enriched in Eastern Finland. Haemochromatosis mutation HFE C282Y homozygosity was 43.8% higher than expected, whereas mutations leading to Bernard-Soulier thrombocytopenia were rare. The frequency of HLA-DQ2/DQ8 genotype was slightly lower than expected. First-degree consanguinity was higher in Blood Service Biobank than in the general population. We demonstrate that despite donor selection, the Blood Service Biobank is a valuable resource for personalised medical research and for genotype-selected samples from unaffected individuals. The geographical genetic substructure of Finland enables efficient recruitment of donors carrying rare variants. Furthermore, we show that blood donor biobank material can be utilised for personalised blood donation policies.
Global emergence of a hypervirulent carbapenem-resistant Escherichia coli ST410 clone
Authors: Ba Xiaoliang , Guo Yingyi , Moran Robert A. , Doughty Emma L. , Liu Baomo , Yao Likang , Li Jiahui , He Nanhao , Shen Siquan , Li Yang , van Schaik Willem , McNally Alan , Holmes Mark A. , Zhuo Chao 
Published: January 2024

AbstractCarbapenem-resistant Escherichia coli (CREC) ST410 has recently emerged as a major global health problem. Here, we report a shift in CREC prevalence in Chinese hospitals between 2017 and 2021 with ST410 becoming the most commonly isolated sequence type. Genomic analysis identifies a hypervirulent CREC ST410 clone, B5/H24RxC, which caused two separate outbreaks in a children’s hospital. It may have emerged from the previously characterised B4/H24RxC in 2006 and has been isolated in ten other countries from 2015 to 2021. Compared with B4/H24RxC, B5/H24RxC lacks the blaOXA-181-bearing X3 plasmid, but carries a F-type plasmid containing blaNDM-5. Most of B5/H24RxC also carry a high pathogenicity island and a novel O-antigen gene cluster. We find that B5/H24RxC grew faster in vitro and is more virulent in vivo. The identification of this newly emerged but already globally disseminated hypervirulent CREC clone, highlights the ongoing evolution of ST410 towards increased resistance and virulence.
Spatiotemporal imaging and shaping of electron wave functions using novel attoclock interferometry
Authors: Ge Peipei , Dou Yankun , Han Meng , Fang Yiqi , Deng Yongkai , Wu Chengyin , Gong Qihuang , Liu Yunquan 
Published: January 2024

AbstractElectrons detached from atoms by photoionization carry valuable information about light-atom interactions. Characterizing and shaping the electron wave function on its natural timescale is of paramount importance for understanding and controlling ultrafast electron dynamics in atoms, molecules and condensed matter. Here we propose a novel attoclock interferometry to shape and image the electron wave function in atomic photoionization. Using a combination of a strong circularly polarized second harmonic and a weak linearly polarized fundamental field, we spatiotemporally modulate the atomic potential barrier and shape the electron wave functions, which are mapped into a temporal interferometry. By analyzing the two-color phase-resolved and angle-resolved photoelectron interference, we are able to reconstruct the spatiotemporal evolution of the shaping on the amplitude and phase of electron wave function in momentum space within the optical cycle, from which we identify the quantum nature of strong-field ionization and reveal the effect of the spatiotemporal properties of atomic potential on the departing electron. This study provides a new approach for spatiotemporal shaping and imaging of electron wave function in intense light-matter interactions and holds great potential for resolving ultrafast electronic dynamics in molecules, solids, and liquids.
Modelling dataset bias in machine-learned theories of economic decision-making
Authors: Thomas Tobias , Straub Dominik , Tatai Fabian , Shene Megan , Tosik Tümer , Kersting Kristian , Rothkopf Constantin A. 
Published: January 2024

AbstractNormative and descriptive models have long vied to explain and predict human risky choices, such as those between goods or gambles. A recent study reported the discovery of a new, more accurate model of human decision-making by training neural networks on a new online large-scale dataset, choices13k. Here we systematically analyse the relationships between several models and datasets using machine-learning methods and find evidence for dataset bias. Because participants’ choices in stochastically dominated gambles were consistently skewed towards equipreference in the choices13k dataset, we hypothesized that this reflected increased decision noise. Indeed, a probabilistic generative model adding structured decision noise to a neural network trained on data from a laboratory study transferred best, that is, outperformed all models apart from those trained on choices13k. We conclude that a careful combination of theory and data analysis is still required to understand the complex interactions of machine-learning models and data of human risky choices.
Simulated outcomes for durotomy repair in minimally invasive spine surgery
Authors: Balu Alan , Kugener Guillaume , Pangal Dhiraj J. , Lee Heewon , Lasky Sasha , Han Jane , Buchanan Ian , Liu John , Zada Gabriel , Donoho Daniel A. 
Published: January 2024

AbstractMinimally invasive spine surgery (MISS) is increasingly performed using endoscopic and microscopic visualization, and the captured video can be used for surgical education and development of predictive artificial intelligence (AI) models. Video datasets depicting adverse event management are also valuable, as predictive models not exposed to adverse events may exhibit poor performance when these occur. Given that no dedicated spine surgery video datasets for AI model development are publicly available, we introduce Simulated Outcomes for Durotomy Repair in Minimally Invasive Spine Surgery (SOSpine). A validated MISS cadaveric dural repair simulator was used to educate neurosurgery residents, and surgical microscope video recordings were paired with outcome data. Objects including durotomy, needle, grasper, needle driver, and nerve hook were then annotated. Altogether, SOSpine contains 15,698 frames with 53,238 annotations and associated durotomy repair outcomes. For validation, an AI model was fine-tuned on SOSpine video and detected surgical instruments with a mean average precision of 0.77. In summary, SOSpine depicts spine surgeons managing a common complication, providing opportunities to develop surgical AI models.
Gonococcal resistance to zoliflodacin could emerge via transformation from commensal Neisseria species. An in-vitro transformation study
Authors: Abdellati Saïd , Laumen Jolein Gyonne Elise , de Block Tessa , De Baetselier Irith , Van Den Bossche Dorien , Van Dijck Christophe , Manoharan-Basil Sheeba Santhini , Kenyon Chris 
Published: January 2024

AbstractOne of the most promising new treatments for gonorrhoea currently in phase 3 clinical trials is zoliflodacin. Studies have found very little resistance to zoliflodacin in currently circulating N. gonorrhoeae strains, and in-vitro experiments demonstrated that it is difficult to induce resistance. However, zoliflodacin resistance may emerge in commensal Neisseria spp., which could then be transferred to N. gonorrhoeae via transformation. In this study, we investigated this commensal-resistance-pathway hypothesis for zoliflodacin. To induce zoliflodacin resistance, ten wild-type susceptible isolates belonging to 5 Neisseria species were serially passaged for up to 48 h on gonococcal agar plates containing increasing zoliflodacin concentrations. Within 7 to 10 days, all strains except N. lactamica, exhibited MICs of ≥ 4 µg/mL, resulting in MIC increase ranging from 8- to 64-fold. The last passaged strains and their baseline were sequenced. We detected mutations previously reported to cause zoliflodacin resistance in GyrB (D429N and S467N), novel mutations in the quinolone resistance determining region (QRDR) (M464R and T472P) and mutations outside the QRDR at amino acid positions 28 and 29 associated with low level resistance (MIC 2 µg/mL). Genomic DNA from the laboratory evolved zoliflodacin-resistant strains was transformed into the respective baseline wild-type strain, resulting in MICs of ≥ 8 µg/mL in most cases. WGS of transformants with decreased zoliflodacin susceptibility revealed presence of the same zoliflodacin resistance determinants as observed in the donor strains. Two inter-species transformation experiments were conducted to investigate whether zoliflodacin resistance determinants of commensal Neisseria spp. could be acquired by N. gonorrhoeae. N. gonorrhoeae strain WHO P was exposed to (i) pooled genomic DNA from the two resistant N. mucosa strains and (ii) a gyrB amplicon of the resistant N. subflava strain 45/1_8. Transformants of both experiments exhibited an MIC of 2 µg/mL and whole genome analysis revealed uptake of the mutations detected in the donor strains. This is the first in-vitro study to report that zoliflodacin resistance can be induced in commensal Neisseria spp. and subsequently transformed into N. gonorrhoeae.