bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of perioperative versus postoperative intratumoral administration of cisplatin for treatment of cutaneous sarcoids and squamous cell carcinomas in horses
Authors: Théon Alain P. , Pascoe John R. , Galuppo Larry D. , Fisher Paul E. , Griffey Stephen M. , Madigan John E. 
Published: December 2023

Objective
To determine the benefits of reducing the interval between surgical cytoreduction and intratumoral administration of cisplatin.

Design
Randomized clinical study.

Animals
70 horses with 89 incompletely resected T2- and T3-stage sarcoids (n = 64) and squamous cell carcinomas (25).

Procedure
Horses were given 4 intratumoral treatments of cisplatin at 2-week intervals. The first treatment was given at the time of, or immediately after, surgical resection for horses treated in accordance with the perioperative protocol (group 1). Horses in group 2 were treated with cisplatin after the skin healed following surgical resection in accordance with the postoperative protocol.

Results
A difference was not found in duration of overall local tumor control between the 2 groups. Patterns of treatment failures and interval to failure differed between the 2 groups. Length of the surgical scar was the only factor that affected prognosis; an increase in length was associated with a poorer prognosis. A detrimental effect of postoperative treatment was only found in tumors with a high tumor proliferative fraction. Local reactions were similar for the 2 treatment groups, and chronic reactions were not observed.

Conclusions and Clinical Relevance
Intratumoral administration of cisplatin is beneficial for treatment of cutaneous tumors in horses. Tumor repopulation during the interval between surgery and intratumoral administration of cisplatin decreases treatment efficacy. These results provide evidence of rapid tumor repopulation following surgical resection without a lag period for tumors with a high proliferation index. When tumor proliferation index is not known, it may be prudent to use the perioperative protocol. (J Am Vet Med Assoc 1999;215:1655–1660)
Usefulness of aerobic microbial culture and cytologic evaluation of corneal specimens in the diagnosis of infectious ulcerative keratitis in animals
Authors: Massa Kathleen L. , Murphy Christopher J. , Hartmann Faye A. , Miller Paul E. , Korsower Carolyn S. , Young Karen M. 
Published: December 2023

Objective
To determine the diagnostic value of aerobic microbial culture and cytologic evaluation of corneal specimens in the diagnosis of infectious ulcerative keratitis (IUK).

Design
Prospective study.

Animals
48 animals (26 dogs, 13 horses, 7 cats, 1 bird, and 1 llama) with corneal ulcers.

Procedure
Scrapings from corneal ulcers were examined cytologically. Corneal swab specimens were submitted for microbial culture. Animals were grouped according to whether they had been receiving antimicrobials at the time of admission.

Results
Of the 38 animals receiving antimicrobials, 19 had positive results for IUK on cytologic evaluation, 20 on microbial culture, and 26 on cytologic evaluation, microbial culture, or both. Of the 10 animals not receiving antimicrobials at the time of admission, 7 had positive results for IUK on cytologic evaluation, and 9 had positive results on microbial culture. In this group of 10 animals, additional animals with IUK were not identified on the basis of cytologic evaluation alone. When all 48 animals were considered irrespective of antimicrobial treatment, 26 and 29 had positive results for IUK on cytologic evaluation and microbial culture, respectively, whereas IUK was confirmed in 35 animals on the basis of cytologic evaluation, microbial culture results, or both.

Conclusions and Clinical Relevance
Microbial culture and cytologic evaluation of corneal specimens maximizes identification of IUK, especially in animals receiving antimicrobial treatment. Because of serious consequences of untreated IUK, we recommend that both diagnostic tests be used to tailor treatment and reduce risk of vision impairment in animals. (J Am Vet Med Assoc 1999;215:1671–1674)
Serum copper concentrations in beef cows and heifers
Authors: Dargatz David A. , Garry Franklyn B. , Clark Gary B. , Ross Paul F. 
Published: December 2023

Objective
To characterize serum copper status of cows and heifers in beef cow-calf herds throughout the United States and to evaluate use of copper supplements in those herds.

Design
Cross-sectional survey.

Animals
2,007 cows and heifers from 256 herds in 18 states.

Procedures
Producers participating in a health and management survey conducted as part of the National Animal Health Monitoring System voluntarily allowed serum samples to be obtained from cows and heifers for determination of copper concentration. Results were categorized as deficient, marginally deficient, or adequate. The proportion of cattle and herds (on the basis of mean value of the tested cattle) in each category was determined. Copper concentrations were compared between herds that reportedly used copper supplements and those that did not.

Results
Overall, 34 of 2,007 (1.7%) cows and heifers were deficient in copper, and 781 (38.9%) were marginally deficient. In each region, at least a third of the cattle were deficient or marginally deficient. For herds, 92 of 256 (35.9%) were marginally deficient, and 22 (0.8%) were deficient. Approximately half of the producers reported use of copper supplements, but a sizeable proportion of those producers' cattle and herds were classified as marginally deficient or deficient.

Conclusions and Clinical Relevance
Copper deficiency is not restricted to a single geographic region of the United States. Copper deficiency can persist despite reported use of supplements by producers. Veterinarians dealing with beef cow-calf herds that have problems consistent with copper deficiency should not rule out copper deficiency solely on the basis of geographic region or reported use of copper supplements for the herd. (J Am Vet Med Assoc 1999;215:1828–1832)
The Haunting of Illa Bella Negreeta: Uncanny Home(Lands) in Bernardine Evaristo’s The Emperor’s Babe
Authors: Macmillan Catherine 
Published: December 2023

Abstract
This paper focuses on Zuleika, a young black inhabitant of Roman Londinium, and her uncanny relationship with her various homes and homelands in Evaristo’s The Emperor’s Babe. It also argues that the novel may provoke a sense of the uncanny in the reader, leading them to question traditional views of classical and British history as “all-white”.
“With a Home Nowhere, I Belong Everywhere”: Travel as a Heterotopic Space of Feminist Resistance in Shivya Nath’s The Shooting Star (2018)
Authors: Talukdar Amrita , Tripathi Priyanka 
Published: December 2023

Abstract
In India, male dominance historically prevailed in the realms of travel and travel writing due to their alignment with ideals of masculine courage and sexuality. However, in the post-millennial era, Indian women began to emerge as solo travelers in the tourism industry, facilitated by increased access to higher education and diverse professions. By analyzing the travel memoir of Shivya Nath, a prominent Indian female travel blogger, titled The Shooting Star (2018), this article explores the concept of solo travel as a heterotopic space—a realm of resistance and negotiation that empowers women and offers an alternative form of liberation. Nath’s memoir celebrates female emancipation, defying narratives of victimhood. The argument presented is that solo travel represents an active form of resistance against gender stereotypes, enabling women to overcome personal fears and logistical obstacles.
From Orthodoxy to the Universal Logic of Human Rights: A Case Study of Film Thappad (The Slap)
Authors: Sharma Navin , Tripathi Priyanka 
Published: December 2023

Abstract
This article analyses the film Thappad (The Slap) (2020) directed by Anubhav Sinha, which portrays slapping as a form of domestic abuse and a violation of women’s right to self-respect. This study investigates the incorporation of Universal Human Rights principles into the discourse of Hindi cinema. Through textual analysis of the film text, the paper examines how the film employs the language of rights as a counter-narrative against patriarchal ideologies, promoting gender equality and dignity within domestic settings. It argues that by countering the conservative cultural perspectives pertaining to spousal abuse through the discourse and philosophy of Human Rights, the film contributes to societal transformation. The paper identifies a shift in the film’s discourse from traditional, orthodox narratives to universal narratives centred around rights.
Multi-Disciplinary and Multi-Objective Optimization Method Based on Machine Learning
Authors: Dai Jiahua , Liu Peiqing , Li Ling , Qu Qiulin , Niu Tongzhi 
Published: December 2023

The optimization of aircraft is a typical multidisciplinary and multi-objective problem. To solve this problem, the difficulty lies not only in the high cost of discipline performance evaluation but also in the complex coupling relationship between different disciplines. To improve the optimization efficiency, a new optimization method is proposed, including two new algorithms: conditional generative adversarial nets with vector similarity (VS-CGAN) and distributed single-step deep reinforcement learning with transfer learning (TL-DSDRL). For low-cost disciplines, VS-CGAN learns the relationship between variables and objectives through presampling to compress the variable domains. The cosine function is used to evaluate the similarity between the random noise and generated variables to avoid mode collapse. For high-cost disciplines, TL-DSDRL improves optimization efficiency through pretraining. The newly designed reward function and multi-agent cooperation mechanism enhance the multi-objective search ability of reinforcement learning.
Assessing Chicken Manure's Competitiveness with Inorganic Nitrogen in Broccoli Production
Authors: KAYMAK Haluk Çağlar , TIRAŞCI Serpil , KAŞKA Mustafa 
Published: December 2023

Objective: This research was undertaken to evaluate the assessment of chicken manure's competitiveness with inorganic nitrogen in broccoli production.
Material and Method: This study was conducted out in field conditions at the experimental area of Atatürk University, Faculty of Agriculture, Department of Horticulture, Erzurum, Türkiye, in 2021 and 2022. Two broccoli cultivars (Brassica oleracea var. italica, Plenk cvs. 'Burney F1' and 'Lucky F1') were used as plant material. While phosphate (200 kg P2O5 ha-1) was kept constant in the plots, 1000 kg ha-1 (CM-1), 2000 kg ha-1 (CM-2), and 4000 kg ha-1 (CM-3) chicken manure were applied additionally. The other application was planned according to the recommended dose of nitrogen (Ammonium nitrate (AN), 200 kg N ha-1). Head weight (g), diameter, and length (cm); dry matter contents of head (%); chlorophyll (SPAD); pH and soluble solid content (SSC) (%) content of heads and yield (kg ha-1) were recorded in harvested heads.
Results: The head weight ranged from 81.2 g (control) to 295.4 g (AN). The head diameter and length changed from 6.4 cm and 4.9 cm (control) to 13.9 cm and 13.6 cm (AN), respectively. The highest chlorophyll (SPAD) content (87.6) was consistently observed in the AN application. CM applications were consistently lower than those from AN application for all cultivars and across both years. Furthermore, in CM applications, the highest yield was attained in 2021 at 16820 kg ha-1 (CM-3, 4000 kg ha-1), whereas the peak yield of 20618 kg ha-1 was recorded in the AN treatment in 2022.
Conclusion: While the yield derived from chicken manure application falls below that achieved through AN application, it is worth noting that, in the context of environmentally sustainable production practices, the utilization of chicken manure at a rate of 4000 kg ha-1 can be advocated. As a result, chicken manure at a rate of 4000 kg ha-1 can be recommended to broccoli producers for environmentally friendly production.
Origins of the ritual of Puliša (CTH 407)
Authors: Ivanov Valerii 
Published: December 2023

The Hittite text of the ritual of Puliša describes the way of counteraction to the plague in the army which returns from a military campaign. The king and his officers should appease the angry gods of the enemy land. Two prisoners are presented to the gods among the ritual carriers.
Puliša’s place of birth and profession are in lacuna that is why it is impossible to determine the ritual tradition which inspired Puliša to compose this text. The only way is to compare this composition with other rites.
The ritual of Zarpiya from Kizzuwatna against pest (CTH 757) contains Luwian incantations. The ritual practitioners ask the gods to stop the epidemic in exchange for the offerings. The ritual of Zarpiya is very different from the ritual of Puliša, while the rituals against plague from Arzawa have a lot in common with the latter. The rituals from Arzawa (CTH 394, 410, 424.1) use the ritual carriers for transporting the epidemic to the enemy and for pacifying the angry gods.
The vocabulary of Puliša’s ritual is close to the one of the royal substitution rituals (CTH 419, 421), which were held for saving a king from the ominous signs. But the sense of the rituals is different. The ritual of Puliša is not focused on the royal power.
The conclusion is reached that the ritual of Puliša was created in the ritual tradition of Arzawa by a scribe that was familiar with the texts of the royal substitution rituals.
Teaching Students to Identify, Document, and Assess Internal Controls
Authors: Behrend Matthew J. , Bradley Jean Ryberg 
Published: December 2023

Abstract
Accounting graduates today need to think critically and evaluate information effectively (Freeman, 2018, citing AICPA, 2016). In particular, accountants need to identify and document business processes and evaluate the associated internal controls. Reflecting these trends, the AICPA (2020) has significantly increased CPA exam coverage of business processes, risk identification, and internal control mapping. This semester-long case, in which students identify and flowchart a business process, uses experiential learning in three areas: internal controls, business-process analysis, and system documentation/flowcharting (Garnsey et al., 2019). It addresses the four key components of experiential learning: Do, Think, Reflect, and Apply; and includes practice in written and oral communication skills (Butler et al., 2019). Unlike many case studies that provide written process narratives, this case requires students to interact with an actual process owner. This interaction helps students develop interpersonal communication skills. Instructors can use this case at the undergraduate or graduate level in either an accounting information systems (AIS) or audit course.
Antibacterial Activity of Andaliman Ethanol Extract (Zantoxylum Acanthopodium Dc.) Against Porphyromonas Gingivalis Bacteria
Authors: Martayuda Yosepa , Kurnia Calvin , Sugiaman Vinna K 
Published: December 2023

Periodontitis is a destructive inflammatory disease of the supporting tissues of the teeth that causes further damage to the periodontal ligament, alveolar bone to the formation of pockets, and decreased gums caused by the bacterium Porphyromonas gingivalis. The most common and frequent periodontal disease is chronic periodontitis which is caused by the accumulation of plaque and calculus. Alternative treatment using herbal ingredients such as andaliman fruit (Zantoxylum acanthopodium DC.) has therapeutic benefits because of its broad biological activity, and lower side effects. Andaliman fruit (Zantoxylum acanthopodium DC.) contains active compounds such as phenolic compounds, saponins, flavonoids, tannins, triterpenoids, steroids, and alkaloids that act as antibacterial. The aim of this study was to determine the minimum inhibitory level (MIC) and minimum killing rate (MBC) of andaliman fruit ethanol extract against Porphyromonas gingivalis bacteria. The research procedure used for the MIC and MBC tests was broth microdilution and the number of colonies was counted using the total plate count (TPC) with variations of 6 concentrations of andaliman fruit ethanol extract with 10% DMSO solvent and 0.2% Chlorhexidine. Statistical analysis in this study was performed using Levene Statistics and Post Hoc Dunnet T3. The ethanol extract of andaliman fruit has a minimum inhibitory concentration (MIC) and a minimum killing concentration (MBC) against the growth of Porphyromonas gingivalis bacteria. The minimum inhibitory concentration in the ethanol extract of andaliman fruit was at a concentration of 25%, while the minimum killing concentration was at a concentration of 100%.
The Effect of Ciplukan Leaves Extract (Physalis minima) Effervescent Tablets as an Denture Cleanser to the Growth Candida albicans
Authors: Soesetijo FX Ady , Kristiana Dewi , 'Aini Berliana Khusnul 
Published: December 2023

Denture stomatitis is one of the problems that often occurs in denture wearers. Prevention of denture stomatitis can be done by immersing the denture in a cleaning solution. Ciplukan leaves (Physalis minima) are natural ingredients that can be used for denture cleaning because they contain antimicrobials. This study aims to determine the effect of effervescent tablets of ciplukan leaf extract (Physalis minima) as a denture cleanser in inhibiting the growth of C. albicans. Methods: This type of research is a laboratory experiment with the post-test-only control group design. The sample used is acrylic resin plate made of heat curing acrylic material The samples used were 24 pieces with a size of 10x10x1 mm which were divided into 4 treatment groups. Samples were immersed in alkaline peroxide effervescent tablets and ciplukan leaf extract effervescent tablets with concentrations of 25%, 50%, and 75% for 20 minutes. The number of C. albicans colonies was counted using a spectrophotometer and converted into the formula. The results of the One-Way ANOVA statistical test showed that the number of C. albicans in each treatment group was significantly different with a significance value of 0,00. Ciplukan leaf extract effervescent tablets were able to inhibit the growth of C. albicans on heat cured acrylic resin plates with the most effective concentration of 75%.
Pelatihan Implementasi Komunikasi Efektif plus Pemasaran Sosial 7P (KEPPS 7P) dalam Pelayanan Kesehatan di Rumah Sakit Setia Mitra Jakarta Selatan
Authors: Rindu Rindu , Novita Astrid , Sihura Sancka Stella Ganiasnda , GP Lazuardi , Reni Reni 
Published: December 2023

Komunikasi efektif dan efisien dalam layanan kesehatan memiliki peran yang vital bagi keselamatan pasien. Tidak hanya dalam menyampaikan informasi pelayanan yang tersedia namun juga saat harus memberikan kabar kurang menyenangkan. Hal ini berdampak pada penurunan kualitas mutu pelayanan rumah sakit sehingga perlu adanya patient care yang optimal yang akan berdampak pada kepuasan pasien. Didalam mewujudkan komunikasi efektif di rumah sakit, setiap staf perlu mengimplementasikan konsep bauran pemasaran 7P yang memiliki 7 elemen yang terdiri dari product, price, promotion, place, people, process serta physical evidence. Berdasar 7 elemen tersebut maka para staf rumah sakit diharapkan bisa mengimplementasikan komunikasi efektif di setiap unit mereka. Pengabdian kepada masyarakat ini bekerjasama dengan Rumah Sakit Setia Mitra Jakarta Selatan. Adapun tujuan dari kegiatan ini adalah diharapkan dapat meningkatkan kompetensi yaitu mampu menjelaskan Teknik Komunikasi, mampu menerapkan Etika Dalam Penampilan Kerja, mampu menerapkan Etika Komunikasi, mampu melaksanakan Manajemen Konfik, mampu melaksanakan Penanganan Komplain, mampu melaksanakan Komunikasi Efektif dan Komunikasi SBAR, serta mampu menerapkan bauran pemasaran 7P. Pengabdian masyarakat berupa pelatihan komunikasi efektif dan pemasaran sosial 7P menunjukkan hasil yang efektif dimana terdapat nilai perbedaan mean 1,08 menunjukkan terdapat selisih rata-rata nilai pengetahuan sebelum (15.81) dan sesudah (16.89) dimana tujuan daripada edukasi dan pelatihan sudah tercapai, yakni perubahan pengetahuan, sikap dan tingkah laku individu, keluarga, kelompok khusus, dan masyarakat.
Upaya Peningkatan Kesehatan Masyarakat Melalui Pengetahuan Dan Pengobatan PTM Di Desa Cikeas Udik
Authors: Liana Duta , Yuliati Yuliati , Pamungkas Rian Adi 
Published: December 2023

Masalah kesehatan fisik masih menjadi ancaman kesehatan masyarakat terutama pada penyakit tidak menular (PTM) misalnya hipertensi, stroke, penyakit jantung dan diabetes mellitus. Secara global, 41 juta orang meninggal setiap tahunnya karena PTM dimana 17 juta meninggal sebelum usia 70 tahun. Peningkatan prevalensi PTM mengindikasikan perlunya mengubah pola hidup sehat. Kegiatan skrining, penyuluhan, dan pengobatan dapat menjadi alternatif pemberdayaan masyarakat. Kegiatan dilaksanakan tanggal 30 September-1 Oktober 2023 di Desa Cikeas Udik, Kabupaten Bogor. Hasil skrining sebanyak 93 orang (88,6%) eligible mendapatkan pengobatan dimana sebagian besar berusia ≥ 46 tahun (52,7%). Lima penyakit terbanyak adalah hipertensi (26,8%), myalgia (13,8%), DM (9,7%), ISPA (7,3%), dan dyspepsia (7,3%). Dalam kegiatan ini diberikan penyuluhan dan edukasi kepada masyarakat meliputi definisi, faktor risiko, pencegahan, pengobatan, penanganan penyakit, pola hidup sehat, olahraga, menjaga pola dan jenis makanan yang dikonsumsi. Kemudian dilaksanakan pengobatan oleh dokter dengan pengobatan terbanyak pada penderita hipertensi, myalgia, dan DM. Harapannya kegiatan ini dapat menjadi upaya peningkatan kesehatan masyarakat dengan meningkatknya pengetahuan dan kesadaran akan pentingnya pencegahan dan pengobatan penyakit tidak menular, khususnya hipertensi dan diabetes mellitus sehingga dapat terkontrol dan menghindari komplikasi. Diperlukan juga keterlibatan aktif kader dan puskesmas setempat dalam meneruskan edukasi kepada warga didesanya tentang penyakit hipertensi dan diabetes mellitus.
СОЦІО-ГУМАНІТАРНА ПУБЛІЧНА ПОЛІТИКА ДЕРЖАВИ В УМОВАХ ВИКЛИКІВ ВІЙНИ
Authors: Титаренко Любов , Костенюк Наталя , Яценко Володимир 
Published: December 2023

У статті розглянуто спрямування публічної політики в напрямку гуманітарно-орієнтованого розвитку держави в епоху викликів під час війни. Сучасний світовий порядок перебуває у стані інтенсивної трансформації, що передбачає перерозподіл важелів впливу і контролю над планетарними ресурсами, глобалізованою фінансово-економічною системою, енергетичною сферою, регуляцією й домінуванням технологічних комунікацій, набуттям контролю над механізмами міжнародної системи безпеки.
Акцентуючи увагу на спрямованості політики держави в умовах викликів війни, ми стали свідками, що іде війна цивілізації з антицивілізацією, усвідомлюючи, що зважена, відповідальна та ефективно – функціонуюча політика потребує гуманітарного підґрунтя з урахуванням кращого світового і європейського досвіду. Звідси і постають питання, що зумовлюють ефективність використання державою людського потенціалу: а) що і в який спосіб суспільство, держава, влада можуть і спроможні дати людям, котрі попали в скрутні життєві обставини внаслідок втрати домівки, майна, рідних та близьких; б) яким чином активізувати морально-етичний світогляд громадян, і, особливо молодого покоління, що активно залучене до відстоювання незалежності країни; в) питання зміни ціннісних орієнтирів громадськості від суспільства споживання до функціональних відносин підтримки людського життя.
Спрямованість політики держави розглядаємо в напрямку вітчизняного цивілізаційного розвитку, захисту України від наявних небезпек війни, суспільних викликів і змін, перспектив відновлення та підтримки громадськості владними структурами.