bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cell-mediated immune response evaluation of live in-vivo attenuated and killed vaccines against Babesia bigemina in calves
Authors: Ullah Naimat , Suleman Muhammad , Ashraf Kamran , Rashid Muhammad Imran , Rehman Abdul 
Published: October 2023

Abstract

The economic significance of babesiosis to the cattle population demands the adoption of alternate, effective and safe prophylactic measures. The current study aimed to develop an effective vaccine against babesiosis caused by B. bigemina. A total (n = 20) six months old, cattle calves were divided into four groups (A, B, C and D; five per group). Group A was inoculated with 2.5 x 106 B. bigemina-infected RBCs propagated and attenuated in-vivo in a rabbit model as a live attenuated vaccine, and Group B was subcutaneously administered with 2 x 106 B. bigemina merozoites as a killed vaccine having Montanide oil. Group C served as the B. bigemina-infected group, while Group D was an uninfected healthy control group. Group B was administered with a booster dose at the same dose on the 14th day post-primary immunization. Both groups, A and B, were challenged with exposure to five B. bigemina-infected Rhipicephalus microplus ticks on the 30th day post-vaccination. Blood samples were collected from all groups at day 0, 7th, and two-week intervals up to three months to evaluate cell-mediated immune response. Group A exhibited the highest cell-mediated immune response among all the groups, with higher protection at post-immunization and post-challenge stage. The significantly higher quantification of CD8 + and CD4 + T cells was associated with the protective potential of live attenuated B. bigemina vaccinated calves (Group A) than killed B. bigemina vaccinated calves (Group B) up to day 100 post-challenge. Based on these results, the live attenuated B. bigemina vaccine from local isolates can be used for prophylaxis against this disease to overcome the economic losses in cattle farming in the future.
Design of a novel cold expansion tool for deep small holes based on FEM simulations and experimental study
Authors: Wang Jiachen , Lei Xue-lin , Fei Zeng , Li Wei , He Cenyao , Cheng Lvyi , Zhang Xiancheng 
Published: October 2023

Abstract
Cold hole expansion is a crucial technology for enhancing the fatigue life of hole structures. This paper presents the design and optimization of a novel multi-convex hulls expansion tool for deep small holes in Inconel 718 superalloy using the finite element method (FEM) and experimental techniques. The results from the FEM model, which was used to investigate the compressive residual stress (CRS) distribution and contact force during the expansion process, indicate that the curved single convex hull(CSCH) structure is more suitable for deep small hole expansion (DSHE). However, accounting for the strength limitations of the actual expansion tool, a multi-convex hulls expansion tool structure was proposed. The FEM model was employed to compare the effects of various tool structures on the hole wall CRS distribution and the contact force during the expansion process. The obtained optimal parameters for enhancing deep small holes in Inconel 718 superalloy under high temperature and high load conditions are as follows: expansion section hull spacing l1 = 0.4 mm, taper ratio C = 0.008, number of convex hulls in the sizing section n = 10, and sizing section hull spacing l2 = 1 mm. Moreover, an optimized convex hull expansion amount allocation scheme was obtained through an experimental study. The results of the FEM simulations and experimental study demonstrate that the optimized multi-convex hulls expansion tool (with an expansion rate of 1.92%) can induce the formation of a high CRS layer and a refined surface without causing significant microcracks in the hole walls.
Evaluation of Thermal-Based Physiological Indicators for Determining Water Stress Thresholds in Drip- Irrigated 'Regina' Cherry Trees
Authors: Carrasco-Benavides Marcos , Espinoza-Meza Sergio , Umemura Kashike , Ortega-Farías Samuel , Baffico-Hernández Antonella , Neira-Román José , Ávila-Sánchez Carlos , Fuentes Sigfredo 
Published: October 2023

Abstract
This work aimed to assess the performance of different thermal-infrared (TIR)-based physiological indicators (PI) as an alternative to the stem water potential (Ψs) and stomatal conductance (gs) for monitor the water status of grafted drip-irrigated 'Regina' cherry trees. In addition, we evaluated the usefulness of piecewise linear regression for finding PI thresholds that are important for post-harvest regulated deficit irrigation (RDI) management. With this purpose, an irrigation experiment was carried out in the post-harvest period. Trees were submitted to three Ψs-based water stress treatments: T0 (fruit grower management treatment, or control) (Ψs > -1.0 MPa, without-to-low water stress); T1 (low to mild water stress treatment = -1.0 > Ψs > -1.5 MPa); and T2 (mild-to-severe water stress treatment = -1.5 > Ψs > -2.0 MPa).
The results indicated that the trees were more stressed in T2 than in T0. In the former, averages of Ψs and gs were -1.75 MPa and 372 mmol m-2 s-1, whereas they were -1.56 MPa and 427 mmol m-2 s-1 in T0. The piecewise model allowed determining the water stress thresholds of almost all studied PI. The breakpoints yielded by this analysis indicated that trees at Ψs lower than -1.5 MPa had a gs lower than 484 mmol m-2 s-1. These results also showed that TIR-based PI, whose equations incorporate a temperature normalization, are a better indicator of cherry tree water status than those without normalization. The derived TIR-based PI threshold values could be used as a reference for managing drip-irrigated 'Regina' cherry trees.
Moderating effect of grip strength in the association between cancer and depressive symptomatology
Authors: Veiga Diogo , Peralta Miguel , Carvalho Laura , Encantado Jorge , Gouveia Élvio , Teixeira Pedro J. , Marques Adilson 
Published: October 2023

Abstract
Purpose
Depression, as one of the leading causes of disease burden, frequently co-occurs with other diseases. Cancer seems to be strongly associated with depression more than any other disease. As an outcome of physical fitness, grip strength seems to have a protective effect on depression. This study aimed to analyse how grip strength moderates the relationship between cancer and depressive symptoms among older European adults.
Methods
Cross-sectional data from wave 8 (2019/2020), including 41701 participants (18003 men) of the population-based Survey of Health, Aging, and Retirement in Europe, were analysed. Grip strength, used as the moderator, was measured twice on each hand using a dynamometer. The EURO-D 12-item scale was used to measure depressive symptoms.
Results
Grip strength had a significant effect as a moderator in the association between cancer and depressive symptoms (male: B= -0.04, 95% CI = -0.04, -0.03; female: B = -0.06, 95% CI = -0.07, -0.06). Also, the grip strength moderation values are below 55.7kg for males and 39kg for females.
Conclusions
Muscular fitness, as measured by grip strength, moderated the relationship between cancer and depressive symptomatology. This supports the theory that recovery programs should include physical activity, namely muscle-strengthening exercises, to prevent depression.
Assessment of Safety and Efficacy in Ambulatory Bilateral same-session Ureterorenoscopy: Results of a Multicenter Study
Authors: Gul Tawiz , Abdelkareem Mohamed , Ebrahim Mohammed , Shehadeh Hamzah , Alnadhari Ibrahim , Salah Morshed 
Published: October 2023

Abstract
Aim:
This study aims to assess the safety and efficacy of Bilateral Same - Session Retrograde Intrarenal Surgery (BSS-RIRS) for bilateral renal stones in ambulatory care settings.
Materials and Methods:
We retrospectively reviewed records from January 2019 to December 2022 for 83 patients who underwent Bilateral Same-Session Retrograde Intrarenal Surgery (BS-RIRS) to manage bilateral renal stones in an ambulatory care setting. Stone clearance was assessed six to eight weeks post-operation via imaging (NCCT KUB, US, or KUB X-ray), defining stone-free status as the absence of fragments or fragments smaller than three millimeters.
Results:
The median stone size was 870 cubic millimeters on the right side (IQR: 452.5 – 1752.5) and 656 cubic millimeters on the left side (IQR: 496.5 – 1276.8). Of the total cohort, 56 patients (68.3%) were pre-stented. The average surgical duration was 105.70 minutes (± 35.97). The stone-free rate (SFR) was 74%, indicating successful clearance. Notably, 13 patients (15.9%) required additional procedures due to incomplete clearance.
Post-operatively, the majority (95.1%) were discharged the same day. However, four patients needed extended stays: one for IV antibiotics, another for bilateral ureteric catheter removal, and two due to surgeon preference. The mean hospital stay was 10.20 hours (± 9.05). Within 30 days post-op, 9 patients (11%) visited the emergency department due to abdominal pain. Four reported hematuria, and 1 had a fever. Importantly, only one patient required hospitalization for IV antibiotics.
Conclusion:
In carefully selected patients, simultaneous bilateral ureterorenoscopy in ambulatory settings is a secure intervention with commendable stone-free rates. This approach offers advantages such as shorter hospitalization, minimized intervention needs, and cost-effectiveness. To achieve these outcomes, selecting patients with a total stone burden of less than 3 cm is crucial.
Trend and disparities in authorship of healthcare-related publications on the ongoing russia- ukraine war
Authors: Alagbo Habib olatunji , Mitra Saloni , Madueke Karen , Azuwike Uchechi Blessing , Ferreira Samantha Dos Santos Rocha , Ademuyiwa Alimat Temitope , Adeleke Oluwaseun , Ejinkeonye Chigozirim , Onyebuchi David Izuchukwu , Atowoju Inioluwa , Odelola Faith Inioluwa , Kumari Jyoti , Sowunmi Marvellous , Al-Inaya Yana , Abdul-Rahman Toufik , Shlobin Nathan A. 
Published: October 2023

Abstract
Background
The Russia-Ukraine war has undeniably impacted global science and healthcare in Ukraine. Many Ukrainian researchers have had their projects disrupted by this war, either due to loss of life, displacement, or destruction of resources. Despite these challenges, these researchers have sought to make their voices heard. This scoping review highlights the trend of healthcare-related publications on the current Russian-Ukrainian war and characterizes the contribution of Ukrainian authors to these publications.
Method
A comprehensive literature search was performed using two databases (Scopus and Pubmed) for publications related to the ongoing Russia-Ukraine war. We included articles only related to healthcare. We then extracted and analyzed bibliometric data.
Result
One hundred and eighty-three articles were identified, including 12 (6.6%) original articles, 26 (14.2%) cross-sectional studies, 19 (10.4%) letters to the editor, 10 (5.5%) commentaries, 5 (2.7%) perspectives, 35 (19.1%) editorials, 2 (1.1%) randomized controlled trials, 11(6.0%) correspondences, 13 (7.1%) opinions, 8 (4.4%) reviews and 42 (23.0%) are identified as others. 180 (98.4%) studies were in English, and 3 (1.7%) were in German. 54 (29.5%) papers on the war had at least one author affiliated with a Ukrainian institution, and 29 (15.9%) studies had authors with Ukrainian affiliation as first authors.
Conclusion
There has been a significant number of publications on the Russia-Ukraine war. Despite the relatively high number of publications, most publications do not arise from the perspective of Ukrainian authors.
Implementation and Evaluation of a Community-based Mindful Walking Randomized Controlled Trial to Sustain Cognitive Health Among Older African Americans at Risk for Dementia
Authors: Yang Chih-Hsiang , Lee Jongwon , Wilcox Sara , Rudisill A. Caroline , Friedman Daniela B. , Hakun Jonathan G. , Neils-Strunjas Jean , Wei Jingkai , Miller Margaret , Byers Megan D. 
Published: October 2023

AbstractBackground With an increasing proportion of older adults and the associated risk of Alzheimer’s Disease and Related Dementias (ADRD) around the globe, there is an urgent need to engage in ADRD risk reduction efforts. African American (AA) older adults in the U.S. are disproportionally impacted by ADRD compared to other races and ethnicities. Mindful walking integrates two potentially protective factors of ADRD by elevating mindfulness and physical activity (i.e., walking), resulting in a synergistic behavioral strategy that is feasible and safe for older adults. However, the efficacy of applying this intervention for cognitive health outcomes has not been evaluated using experimental designs. Methods This paper documents the goal and protocol of a community-based, mindful walking randomized controlled trial to examine the short- and longer-term efficacy on cognitive and other health-related outcomes in ADRD at-risk AA older adults. The study outcomes include various brain health determinants, including cognitive function, quality of life, psychological well-being, physical activity, mindfulness, sleep, and overall health status. In addition, the estimated costs of program implementation are also collected throughout the study period. This study will recruit 114 older adults (ages 60 + years) with elevated ADRD risk from the Midlands region of South Carolina. Older adults are randomly assigned to participate in 24 sessions of outdoor mindful walking over three months or a delayed mindful walking group (n = 57 in each group). Participants in both groups follow identical measurement protocols at baseline, after 12 weeks, after 18 weeks, and after 24 weeks from baseline. The outcome measures are administered in the lab and in everyday settings. Costs per participant are calculated using micro-costing methods. The eliciting participant costs for mindful walking engagement with expected results are reported using the payer and the societal perspectives. Discussion This study will generate evidence regarding the efficacy of mindful walking on sustaining cognitive health in vulnerable older adults. It can inform future large-scale effectiveness trials to support our study findings. If successful, this mindful walking program can be scaled up as a low-cost and viable lifestyle strategy to promote healthy cognitive aging in diverse older adult populations, including those at greatest risk. Trial registration: ClinicalTrials.gov number NCT06085196 (retrospectively registered on 10/08/2023)
Poor quality, pro-inflammatory diet in children with Crohn’s disease and healthy controls: a cross-sectional study
Authors: Breton Jessica , Quinn Ryan , Conrad Máire , Kachelries Kelly , Schwab Erica , Baldassano Robert , Albenberg Lindsey , Compher Charlene 
Published: October 2023

Abstract

Background:
Diet plays a critical role in development and progression of Crohn’s disease (CD). Dietary indices are important tools to evaluate diet quality and dietary inflammatory potential, and we investigated the associations of it with pediatric CD.
Method:
A cross-sectional study including 144 children with CD (122 with clinically active and 22 with quiescent disease) and 57 healthy controls 6-18 years of age was conducted. Dietary intake was estimated using three 24-h dietary recalls. Diet quality was assessed using the Healthy Eating Index (HEI)-2015, alternate Mediterranean diet (aMed) score and modified Children-Dietary Inflammatory Index (mC-DII).
Results:
Children with active CD had lower total HEI-2015 and aMed scores than healthy controls. A similar pro-inflammatory mC-DII score was found across the three groups. A higher mC-DII score in patients with CD was associated with higher intake of refined sugars, saturated fats and proteins, and lower intake of whole grains and dairy. Fiber intake was significantly lower in children with active CD (median fiber DRI: 37.0 [22.6-48.3] vs 41.2 [34.1-49.1] vs 45.8 [35.7-62.0], P <0.001).
Conclusions:
Using three dietary indices to evaluate diet quality, both children with CD and healthy children in North America consume a poor-quality, pro-inflammatory diet low in fiber, but the quality and fiber content are significantly lower in children with active CD. Future randomized controlled trials are required to evaluate the effect of the change in diet and secondarily dietary quality scores on the risk and progression of pediatric CD.
Structural and magnetic properties of Lu doped SrFe12O19 ferrites
Authors: Wang Huang-Yi , Han Jia-Jun 
Published: October 2023

Abstract
In this work, M-type strontium ferrite LuxSrFe12−xO19 (x = 0, 0.2, 0.4, 0.6) was prepared using a precursor chemical co-precipitation method. The structures, morphologies, and elemental compositions of the samples were analyzed using X-ray diffraction (XRD) and scanning electron microscopy (SEM). The magnetic properties of the prepared samples were determined using a vibrating sample magnetometer (VSM). XRD peaks revealed its crystalline nature, exhibiting a hexagonal single-phase magnetic spinel crystal structure. SEM micrographs displayed regular hexagonal grain structures, with the grain size gradually decreasing with increasing Lu3+ ions content. VSM analysis confirmed that LuxSrFe12−xO19 is essentially a hard magnetic material with significant coercivity, and the saturation magnetization and remanent magnetization exhibited a trend of initially decreasing and then increasing with the increasing Lu3+ ions content. Furthermore, Lu3+ ions substituted SrFe12O19 ferrites find wide applications in magnetic recording and memory devices.
Researchers’ views on and practices of knowledge translation: an international survey of transfusion medicine researchers
Authors: Thijsen Amanda , Masser Barbara , Davison Tanya Ellen , Williamson Anna 
Published: October 2023

Abstract
Background: Health research is often driven by the desire to improve the care and health of the community; however, the translation of research evidence into policy and practice is not guaranteed. Knowledge translation (KT) activities, such as dissemination and end-user engagement by researchers, are important to achieving this goal. This study examined researchers’ views on and practices of KT in the field of transfusion medicine.
Methods: An anonymous, cross-sectional survey was distributed to transfusion medicine researchers in May 2022 by emailing corresponding authors of papers in four major blood journals, emailing grant recipients, posting on social media, and through international blood operator networks. Comparative analyses were conducted for career stage, work setting, research type, and KT training.
Results: The final sample included 117 researchers from 33 countries. Most participants reported that research translation was important (86%) and felt it was their responsibility (69%). Fewer than half felt they had the skills to translate their research (45%) or knew which strategies to employ (45%). When examining how research findings are shared, most reported using diffusion activities (86%), including publishing in peer-reviewed journals (74%), or presenting at academic conferences (72%). Fewer used dissemination methods (60%), such as developing educational materials (29%) or writing plain language summaries (30%). Greater use of tailored dissemination strategies was seen among researchers with KT training, while traditional diffusion strategies were used more by those working in an academic setting. Most participants had engaged end-users in their research (72%), primarily to consult on a research component (47%) or to involve them in the research process (45%). End-user engagement was greater among researchers with established careers, working in both an academic and applied setting, and with KT training.
Conclusions: While participating researchers acknowledged the importance of KT, they typically focused on traditional diffusion strategies. This is despite well-established knowledge of the limited impact of these strategies in achieving KT. Those with KT training were more likely to use tailored dissemination strategies and engage end-users in their research. This demonstrates the value of sharing knowledge from the KT field with health researchers to facilitate KT.
Coverage and use of improved sanitation facilities at household level after implementation of National Sanitation Campaign in Siha District, Kilimanjaro Region, Tanzania
Authors: Bernad Fina , Sakwari Gloria , Luoga Pankras , Nyaboke Jemima 
Published: October 2023

Abstract
Introduction Improved sanitation and hygiene practices coverage and use are still very low worldwide. The situation is worse in developing countries and sub-Saharan Africa, as one person in five has sanitation services. Before implementing the National Sanitation Campaign (NSC), Tanzania, particularly Siha District, had an estimated 21% and 15% coverage for improved toilets and functional handwashing facilities, respectively. In comparison, 5.7% of households practiced open defecation. Therefore, this study intended to assess factors and changes brought about by the NSC intervention and the sustainability of the improved sanitation facilities two years after the intervention ended. Materials and Methods The study was conducted in Siha District, Kilimanjaro Region, using a cross-sectional pre- and post-study design with a quantitative approach. Cluster sampling was used to select households from the four villages in the district. The post-intervention data were collected using interviewing and observation methods to assess the coverage and use of improved sanitation facilities and factors for its sustainability. All objectives were analyzed using Statistical Package for Social Sciences version 21 (SPSS). Results The study revealed increased coverage of households with improved latrines and handwashing facilities. The HH with improved toilets increased from 21–36.3%, and handwashing facilities increased from 15–15.9% after the intervention. There was a decrease in open defecation practices from 5.7–3.9%. Income (AOR = 2.9, 95% CI (1.79–4.96) and education (OR = 3.33, 95% CI ((1.53–7.725), were the significant factors for the sustainability of improved sanitation facilities. Conclusion The sanitation campaign brought about the desired changes in improving household sanitation and hygiene practices. The Health and Environmental Village committees should provide education on the benefits of construction and use of the improved toilets and handwashing facilities to reduce OD (Open Defecation) practices and disease spread among household members in the setting.
Effect of Annealing Temperature on the Microstructure and Properties of 2024 Aluminum Alloy with Large Deformation
Authors: Jian Haigen , Wu jiangyao , Chen Miao , Xiao Kemou , Pai Junjun 
Published: October 2023

Abstract
The findings demonstrate that as the annealing temperature is raised, the proportion of low angle grain boundaries (2-15°, LAGB) in the 2024 aluminum alloy falls, and the proportion of high angle grain boundaries (≤15°, HAGB) increases. The strength and hardness of the alloy drop as the degree of recrystallization rises, but the plasticity and toughness rise. The texture becomes less intense, and there is an evolution path of Brass + Copper → R-Cu + m-Brass + Cu35° + α55° + {101}<232> → P0° + Goss → V + F. Σ3 coincidence site lattice (CSL) grain boundary's volume fraction grows, increasing the grain boundary's resistance to corrosion.