bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lifestyle and Sense of Coherence: A comparative analysis among university students in different areas of knowledge
Authors: Braga João Paulo Costa , Wolfgram Eduardo , Batista de Souza João Paulo , Fausto Silva Larissa Gabriele , Estavien Yonel , de Almeida Roberto , Pestana Cezar Rangel 
Published: September 2023

Background
The concept of health has undergone profound changes. Lifestyle Medicine consists of therapeutic approaches that focus on the prevention and treatment of diseases. It follows that the quality of life of university students directly affects their health and educational progress.

Experimental methodology
Socioeconomic, lifestyle (LS), and Salutogenesis Theory/sense of coherence (SOC) questionnaires were administered to college students from three different areas. The results were analyzed for normality and homogeneity, followed by ANOVA variance analysis and Dunn and Tukey post hoc test for multiple comparisons. Spearman’s correlation coefficient evaluated the correlation between lifestyle and sense of coherence; p values < 0.05 were considered statistically significant.

Results
The correlation between LS and SOC was higher among males and higher among Medical and Human sciences students compared to Exact sciences. Medical students’ scores were higher than Applied sciences and Human sciences students on the LS questionnaire. Exact science students’ scores on the SOC questionnaire were higher than Human sciences students. In the LS areas related to alcohol intake, sleeping quality, and behavior, there were no differences between the areas. However, women scored better in the nutrition domain and alcohol intake. The SOC was also higher in men compared to women.

Conclusion
The results obtained demonstrate in an unprecedented way in the literature that the correlation between the LS and SOC of college students varies according to gender and areas of knowledge, reflecting the importance of actions on improving students’ quality of life and enabling better academic performance.
Impact of anthropometry training and feasibility of 3D imaging on anthropometry data quality among children under five years in a postmortem setting
Authors: Gupta Priya M. , Sivalogan Kasthuri , Oliech Richard , Alexander Eugene , Klein Jamie , Addo O. Yaw. , Gethi Dickson , Akelo Victor , Blau Dianna M. , Suchdev Parminder S. 
Published: September 2023

Background
The Child Health and Mortality Prevention Surveillance Network (CHAMPS) identifies causes of under-5 mortality in high mortality countries.

Objective
To address challenges in postmortem nutritional assessment, we evaluated the impact of anthropometry training and the feasibility of 3D imaging on data quality within the CHAMPS Kenya site.

Design
Staff were trained using World Health Organization (WHO)-recommended manual anthropometry equipment and novel 3D imaging methods to collect postmortem measurements. Following training, 76 deceased children were measured in duplicate and were compared to measurements of 75 pre-training deceased children. Outcomes included measures of data quality (standard deviations of anthropometric indices and digit preference scores (DPS)), precision (absolute and relative technical errors of measurement, TEMs or rTEMs), and accuracy (Bland-Altman plots). WHO growth standards were used to produce anthropometric indices. Post-training surveys and in-depth interviews collected qualitative feedback on measurer experience with performing manual anthropometry and ease of using 3D imaging software.

Results
Manual anthropometry data quality improved after training, as indicated by DPS. Standard deviations of anthropometric indices exceeded limits for high data quality when using the WHO growth standards. Reliability of measurements post-training was high as indicated by rTEMs below 1.5%. 3D imaging was highly correlated with manual measurements; however, on average 3D scans overestimated length and head circumference by 1.61 cm and 2.27 cm, respectively. Site staff preferred manual anthropometry to 3D imaging, as the imaging technology required adequate lighting and additional considerations when performing the measurements.

Conclusions
Manual anthropometry was feasible and reliable postmortem in the presence of rigor mortis. 3D imaging may be an accurate alternative to manual anthropometry, but technology adjustments are needed to ensure accuracy and usability.
Quantitative sonographic assessment of muscle thickness and fasciculations distribution is a sensitive tool for neuromuscular disorders
Authors: Abraham Alon , Fainmesser Yaara , Drory Vivian E. , Bril Vera 
Published: September 2023

Introduction
Loss of muscle thickness can be demonstrated in a wide spectrum of neuromuscular disorders, while fasciculations are more frequent in amyotrophic lateral sclerosis (ALS). In the current study, we aimed to determine the sensitivity and specificity of quantitative sonographic assessment of muscle thickness and the presence of fasciculations for diagnosing various neuromuscular disorders.

Methods
The thickness and the presence of fasciculations in eight muscles were determined by sonography in patients with myopathy (22), polyneuropathy (36), ALS (91), and spinal muscular atrophy (SMA) (31) and compared to normative values determined in 65 heathy control subjects.

Results
Reduced muscle thickness in at least one relaxed muscle showed 92–100% sensitivity for diagnosing a neuromuscular disease, with a specificity of 85% for differentiating patients from heathy controls (AUC = 0.90). Subtracting distal from proximal muscle thickness may differentiate between myopathy and polyneuropathy. Fasciculations in ≥1 proximal muscle showed good diagnostic accuracy (AUC = 0.87) for diagnosing ALS.

Discussion
Sonographic assessment of muscle thickness is a sensitive tool for diagnosing a wide spectrum of neuromuscular diseases, and may facilitate diagnosis even in patients with normal strength on neurological examination, while the presence of fasciculations in proximal muscles may facilitate ALS diagnosis.
A Decade of Research Into Second Language Acquisition: A State-of-the-Science Review (2009-2019)
Authors: Wang Huili , Guo Hanning , Yang Lianrui , Wolter Brent 
Published: September 2023

Abstract
This study investigated the knowledge domain of second language acquisition (SLA) research in 2009-2019. It selected about a decade of studies in the SLA knowledge domain and applied an available data analysis tool CiteSpace to show a picture of SLA research. The 11-year period of studies was retrieved from the Web of Science database, totally 4, 660 bibliographic records. By employing the embedded algorithm analyzing literature in CiteSpace, the present study found the factors influencing SLA and statistical models were critical aspects in L2 research, and research topics were conducted in psychological, neuroscience, linguistic, and language teaching frameworks. Additionally, research patterns in the SLA domain have become more diversified, and empirical studies of cognitive science have gradually taken a dominant position in recent years. Spikes of increased numbers of detected papers in the period of 2009-2019 showed research focus and methodology would possibly continue to be interdisciplinary in future research.
Chinese Learners’ Use of Translation in Learning Academic Subjects in English-Medium Instruction Context
Authors: Zhang Xiaohan , Zou Bin 
Published: September 2023

Abstract
Many researchers have identified learning strategies that university students adopt to overcome difficulties in programs taught in English, among which translation is a potentially helpful one. This study explores Chinese undergraduate students’ perceptions of translation as a learning strategy when learning content in the English-medium instruction (EMI) context. Although a number of studies have investigated translation used by learners in second or foreign language acquisition, those studies were rare in the EMI context of tertiary education, particularly in China. By focusing on students’ perspectives, this study provides an insight into how translation is used to assist academic learning in EMI context and highlights its effectiveness. Data consisted of semistructured interviews with 14 volunteer Chinese undergraduates of various majors. It is found that most of the participants resorted to translation to deal with language-related problems, especially in English reading and writing activities. They usually translated utilizing various machine translators, which did not always have a fulfilling effect on students’ learning. Although the majority considered translation helpful for academic learning, it might not be the preferred solution to subject-related confusion for Chinese undergraduate students learning in the EMI context.
Second Language Learners Listening to their Peers: Is There a Shared L1 Effect for L2 Comprehensibility and Accentedness?
Authors: Tergujeff Elina 
Published: September 2023

Abstract
Previous research on the perception of second-language speech has suggested that non-native listeners may benefit from sharing the speakers’ first language, e. g. speakers of Spanish find Spanish-accented English easy to understand. In the present study, L2 English speech samples elicited from L1 Finnish and L1 Finland-Swedish speakers were rated for comprehensibility and accentedness by English-speaking listeners and the speakers’ peers, seeking to explore whether there is a difference between the listener groups. In addition, the speakers’ overall spoken proficiency (A2, B1, B2 on the CEFR scale) was considered in the analysis to find out if the possible shared L1 effect is connected to the speakers’ proficiency. The results were mixed, finding that L1 Finland-Swedish listeners were more lenient towards their peers’ English than the English-speaking listeners were, whereas L1 Finnish listeners gave comprehensibility ratings equal to those given by English-speaking listeners, and accentedness ratings that were stricter. The finding supports earlier suggestions on the effects of sharing the speakers’ L1 for L2 speech perception being L1 dependent. As for the influence of the speakers’ proficiency, the results demonstrate a greater difference between English-speaking listeners and listeners who share the speakers’ L1 regarding low-proficiency speakers.
HMGB1-RAGE axis contributes to myocardial ischemia/reperfusion injury via regulation of cardiomyocyte autophagy and apoptosis in diabetic mice
Authors: He De-Wei , Liu De-Zhao , Luo Xiao-Zhi , Chen Chuan-Bin , Lu Chuang-Hong , Na Na , Huang Feng 
Published: September 2023

Abstract
Patients with acute myocardial infarction complicated with diabetes are more likely to develop myocardial ischemia/reperfusion (I/R) injury (MI/RI) during reperfusion therapy. Both HMGB1 and RAGE play important roles in MI/RI. However, the specific mechanisms of HMGB1 associated with RAGE are not fully clarified in diabetic MI/RI. This study aimed to investigate whether the HMGB1-RAGE axis induces diabetic MI/RI via regulating autophagy and apoptosis. A db/db mouse model of MI/RI was established, where anti-HMGB1 antibody and RAGE inhibitor (FPS-ZM1) were respectively injected after 10 min of reperfusion. The results showed that treatment with anti-HMGB1 significantly reduced the infarct size, serum LDH, and CK-MB level. Similar situations also occurred in mice administrated with FPS-ZM1, though the HMGB1 level was unchanged. Then, we found that treatment with anti-HMGB1 or FPS-ZM1 performed the same effects in suppressing the autophagy and apoptosis, as reflected by the results of lower LAMP2 and LC3B levels, increased Bcl-2 level, reduced BAX and caspase-3 levels. Moreover, the Pink1/Parkin levels were also inhibited at the same time. Collectively, this study indicates that the HMGB1-RAGE axis aggravated diabetic MI/RI via apoptosis and Pink1/Parkin mediated autophagy pathways, and inhibition of HMGB1 or RAGE contributes to alleviating those adverse situations.
Reflection 6593: Kant’s Rousseau and the Vocation of the Human Being
Authors: Kryluk Michael 
Published: September 2023

Abstract
In this essay, I examine Kant’s interpretation of Rousseau through the lens of Reflection 6593. This Reflection deserves scrutiny because it serves as a bridge between Kant’s well-known engagement with Rousseau in the mid-1760s and his later discussions of the vocation of the human being in the lectures on ethics and anthropology. Through a close reading of R 6593, I argue that the Reflection offers the earliest evidence of Kant’s philosophy of history and its integration into his treatment of the human vocation. This change, I propose, is instigated by Rousseau’s “Abstract” of St. Pierre’s Perpetual Peace. I conclude that R 6593 is a crucial indicator of Kant’s evolving views on Rousseau and shows his enduring importance for understanding the formation of Kant’s mature political thought.
Ethics and Social Responsibility in Information Behavior, an Interdisciplinary Research in Uruguay
Authors: Sabelli Martha 
Published: September 2023

Abstract
This article presents a series of projects focused, within the framework of the ethical and social responsibility of a Latin American public university, on the information behavior of disadvantaged people, developed from 2008 to the present, within the Information Institute of the University of the Republic, Uruguay. They arose from the views and ideas supported by the project leaders and teams concerning the deficiencies and limitations in the access, use, and appropriation of necessary, relevant, valuable, and reliable information for the personal and social development of social sectors in unfavorable situations in the contexts in which they live. Each of the studies has real social impacts on information policy agendas, incorporating actions to achieve the 2030 Agenda. The projects comprise the theoretical and methodological perspectives presented in each one on the field of information behavior and related to each situation problem identified in a specific user community. The research subjects were young women (2008–2010), adolescents (2010–2015), older women (2017–2019), and family members of children with autism spectrum syndrome (ASD) (2021–2023). We seek to understand the social realities of information and information technologies insofar as most investigations incorporate the development and use of ICTs in the quest to disseminate inclusive information.
Epistemic modality and grounding: constructions expressing positive epistemic judgement in Spanish and Italian from the perspective of cognitive grammar (with particular reference to the verbs credere and creer)
Authors: Kratochvílová Dana 
Published: September 2023

Abstract
This paper examines the means of expressing positive epistemic judgement in Spanish and Italian: modals in their epistemic interpretation, epistemic adverb + indicative/subjunctive, with particular attention to the verbs creer/credere and their possible combination with the subjunctive. The constructions are analysed through the prism of cognitive grammar, specifically Langacker’s theory of grounding. It is argued that the different types of epistemic judgement are analogous to nominal grounding elements (demonstrative pronouns, the definite article and relative quantifiers). The subjunctive after epistemic adverbs and verbs (such as tal vez or credere) is seen as the verbal counterpart of the relative quantifier some. Analyses suggest that this analogy helps to define the semantic difference between similar structures with the indicative and to resolve questions concerning the function of the subjunctive in epistemic contexts, such as the degree of uncertainty or the speaker’s attitude towards the propositional content.
Synthesis and surface properties of branched-chain tertiary fatty alcohol sulfate surfactants
Authors: Wang Qian , Li Xu , Dong Jinxiang 
Published: September 2023

Abstract
In this paper, anionic branched-chain tertiary fatty alcohol sulfate surfactants were synthesized from n-hexene and n-octene using selective olefin dimerization, hydration reaction (hydroxylation), and sulfur trioxide sulfation. The direct hydration reaction of the α-olefin dimer 2-butyl-1-octene with water as a model reaction was explored for the synthesis of branched-chain tertiary fatty alcohols. Two branched-chain tertiary fatty alcohol sulfate surfactants, namely C12-SBTAS and C16-SBTAS, with different carbon chain lengths, were synthesized by the sulfur trioxide sulfation method. Their structures were confirmed by various analytical techniques, including HPLC, FT-IR, HR-MS, and 1H NMR. Equilibrium and dynamic surface tension, foaming, wetting, and emulsifying properties were compared with those of Guerbet cetyl alcohol sulfate (C16-SGAS). C12-SBTAS and C16-SBTAS exhibited good surface activity with equilibrium surface tension (γ
CMC) values of 27.41 mN m−1 and 26.69 mN m−1, respectively. They also had low foaming and rapid defoaming abilities, as well as good wetting and emulsifying properties, which match the application characteristics of typical branched-chain surfactants.
En torno al pseudoanglicismo acuñado por traducción
Authors: Lillo Antonio 
Published: September 2023

Abstract
The study of pseudo-English words arising as translations of Spanish lexemes and expressions has been largely overlooked, if not deliberately ignored, by scholars working in the field of Anglicisms. There are several reasons for this, but the most important is surely that the type of translation involved in the coinage of these words goes right against the grain of what is deemed conventional, common-or-garden calquing. A lexical or phrasal unit coined as a calque of a Spanish word or phrase may look English, but is actually Spanish. On occasion, a Spanish word or word element may also be jocularly interpreted as if it were English, thus lending itself to playful calquing into Spanish. Drawing on a corpus of over 2,000 citations from the microblogging site Twitter, this article provides a detailed analysis of the processes used to create Spanish-based false Anglicisms, usually for playful or humorous effect. The bottom line of this analysis is that these calqued formations are generally motivated by a desire to undermine the sophistication and prestige associated with the use of English loanwords in Spanish.
SOSYO-EKONOMİK SONUÇLARI AÇISINDAN 1935 ERDEK-MARMARA ADASI DEPREMİ
Authors: KUMAŞ Nursal 
Published: September 2023

Deprem kuşağında yer alan Türkiye’de meydana gelen sarsıntıların bir kısmı insan ve mal kaybına neden olabilmektedir. Nitekim 4 Ocak 1935 Cuma günü merkez üssü Balıkesir’in Erdek ilçesine bağlı Marmara Adası olan 6,4 büyüklüğünde bir deprem meydana geldi. Çevre il ve ilçelerden de hissedilen bu deprem sonucunda birçok kişi yaralanırken resmi rakamlara göre 5 kişi hayatını kaybetti ve 600 bina da hasar gördü. Deprem en çok Marmara Adası nahiyesine bağlı köyleri etkiledi. Depremin artçı sarsıntılarının günlerce devam etmesi bölgedeki yıkımın etkisini artırdı. Bölgede kış koşullarının ağır geçmesi, fırtına, yağmur ve soğuk hava yardım faaliyetlerini olumsuz yönde etkiledi. Depremzedeler önce çadırlarda daha sonra da kendileri için yapılan barakalarda iskân edildiler.
Deprem bölgesinden Erdek Kaymakamı Esat Bey aracılığıyla elde edilen bilgiler Dâhiliye Vekâleti, Sıhhat ve İçtimai Muavenet Vekâleti ve Hilali Ahmer Cemiyeti Genel Merkezi’yle telgraf yoluyla paylaşıldı. Balıkesir valiliğinin koordinasyonuyla depremzedelere iaşe, ibate, iskân ve evlerin tamirinin gerçekleştirilmesi için bir yardım komitesi oluşturuldu. Komisyon Bandırma’yı kriz merkezi haline getirerek deprem bölgesine yardım sevkiyatını gerçekleştirdi. Ayrıca Dâhiliye Vekâleti Teftiş Heyeti Reisi İbrahim Sabri Çıtak’ı, Sıhhat ve İçtimai Muavenet Vekâleti de Başmüfettiş Dr. Fuad Sorağman’ı incelemeler yapmak üzere bölgeye gönderdi. Her iki müfettiş bölgede yaptıkları gözlemlerini ve yardım faaliyetlerini raporlar halinde ilgili bakanlıklara sundular. Bu çalışmada söz konusu teftiş raporları, Cumhurbaşkanlığı Devlet Arşivleri Başkanlığı Cumhuriyet Arşivi (BCA) Belgeleri ve dönemin gazetelerinden yararlanılarak depremin sosyo ekonomik sonuçları üzerinde duruldu.
Monomeric agonist peptide/MHCII complexes activate T‐cells in an autonomous fashion
Authors: Platzer René , Hellmeier Joschka , Göhring Janett , Perez Iago Doel , Schatzlmaier Philipp , Bodner Clara , Focke‐Tejkl Margarete , Schütz Gerhard J , Sevcsik Eva , Stockinger Hannes , Brameshuber Mario , Huppa Johannes B 
Published: September 2023

AbstractMolecular crowding of agonist peptide/MHC class II complexes (pMHCIIs) with structurally similar, yet per se non‐stimulatory endogenous pMHCIIs is postulated to sensitize T‐cells for the recognition of single antigens on the surface of dendritic cells and B‐cells. When testing this premise with the use of advanced live cell microscopy, we observe pMHCIIs as monomeric, randomly distributed entities diffusing rapidly after entering the APC surface. Synaptic TCR engagement of highly abundant endogenous pMHCIIs is low or non‐existent and affects neither TCR engagement of rare agonist pMHCII in early and advanced synapses nor agonist‐induced TCR‐proximal signaling. Our findings highlight the capacity of single freely diffusing agonist pMHCIIs to elicit the full T‐cell response in an autonomous and peptide‐specific fashion with consequences for adaptive immunity and immunotherapeutic approaches.
The p53 Family of Transcription Factors Represses the Alpha- fetoprotein Gene Expression in Hepatocellular Carcinoma
Authors: Wölfel Gisela , Ostheim Elisabeth , Staub Agnes , Tümen Deniz , Heumann Philipp , Schmid Stephan , Schlosser Sophie , Müller Martina , Gulow Karsten , Kunst Claudia 
Published: September 2023

Background: p53 deletion and mutation as well as upregulation of alpha-fetoprotein (AFP) are hallmarks of hepatocarcinogenesis. p63 and p73 belong to the family of p53-related transcription factors expressing a variety of isoforms. The expression of dominant negative (ΔN) p73 is related to the reduced survival of patients with hepatocellular carcinoma (HCC). In this study, we characterized the interaction between p53 family-dependent signaling pathways and the regulation of AFP at the gene and protein levels as essential determinants of therapeutic response and prognosis in HCC.
Methods: Putative p53-, p63- and p73-binding sites within the AFP gene were identified in silico. Hep3B cells were transfected with plasmids encoding for p53, p63 and p73 to analyze the interplay of the p53 family with AFP. AFP transcription was determined by RT-qPCR. Protein levels of AFP, p53, p63 and p73 were analyzed by Western blot.
Results: Underlining the importance of the crosstalk between the p53 family-dependent pathways and AFP regulation we identified eight novel putative binding sites for the members of the p53 family within the introns 1, 2, 3, 4, 7, 8, 11, and 12 of the AFP gene. Accordingly, full-length isoforms of p53, p63 and p73 efficiently downregulated AFP both on mRNA and protein level. Thus, the p53 family members were identified to be major regulators of AFP repression. Of note, p63 was characterized as a novel and p73 as the most efficient repressor of AFP.
Conclusion: p53 mutation and upregulation of AFP are essential oncogenic events in the development of HCC. Here we show that AFP gene regulation occurs via a combined action of the p53 family members p53, p63 and p73. All three tumor suppressors reduce AFP gene and protein expression. Thus, our findings reveal a novel interaction of p53 family-dependent signaling pathways and AFP regulation at the gene and protein levels in HCC.