bluuebunny/crossref_metadata_2025_split huggingface dataset:
Canola bee pollen is an effective artificial diet additive for improving larval development of predatory coccinellids: a lesson from Harmonia axyridis
Authors: Sun Yuan‐Xing , Chen Ming‐Juan , Hao Ya‐Nan , Wang Sen‐Shan , Zhang Chu‐Lin 
Published: January 2024

AbstractBACKGROUNDPollen is a common plant‐derived food source for predatory ladybird beetles under field conditions, yet the potential for pollen to improve the quality of artificial diets remains largely unexplored. In this study, we developed three pollen diets by incorporating varying proportions of canola bee pollen (7.5%, 15.0% and 22.5% with 2.5%, 5.0%, and 7.5% of water, respectively) into a conventional diet. The feeding efficiency of Harmonia axyridis, an omnivorous predator, was evaluated and compared on three pollen diets, a conventional nonpollen diet and pea aphids.RESULTSThe larvae fed a medium or high pollen diet exhibited significantly higher survival in the 4th instar, pupa and adult stages than those fed a nonpollen diet. These larvae also developed into significantly heavier adults, and their survival rates in adulthood were comparable to those fed pea aphids. Specifically, we revealed the underlying mechanisms through which a high pollen diet enhances pupal development. Consumption of high pollen diet versus nonpollen diet resulted not only in a significant decrease in pupal glycogen content, but also an increase in adult lipid content. Both diet treatments induced similar changes in carbohydrate and glycogen content compared to the aphid diet while exhibiting different alterations in pupal protein content and adult lipid content. Furthermore, the transcriptome analysis revealed that the nutrient metabolism, immune response, and cuticle development pathways were predominantly enriched among the differentially expressed genes (DEGs).CONCLUSIONCanola bee pollen offers diverse advantages in terms of rearing H. axyridis larvae with an artificial diet, which will advance the development of effective diets for predaceous coccinellids. © 2024 Society of Chemical Industry.
Public health consequences of armed conflict in Sudan in the face of global donor fatigue
Authors: Musa Muhammad Kabir , Eshun Gibert , Modber Mohamed Abdulkareem Adam , Haruna Usman Abubakar , Abdulsalam Abdullateef , Zailani Asma'u Shuaibu , Zakariya Farida , Adamu Nuruddeen Abubakar , Musa Mohamed Babiker , Biney Godness Kye 
Published: January 2024

AbstractSudan, a country located in northeastern Africa, is grappling with a profound health crisis resulting from the recent war that erupted on April 15, 2023. This conflict has inflicted significant damage on the country's health system, particularly through the destruction of healthcare infrastructure. Approximately 61% of health facilities have been destroyed, leaving only 16% operating optimally in Khartoum. Hospitals and clinics, vital for public health, have become targets of violence, exacerbating the challenges faced by the nation. The World Health Organization has noted the closure of roughly 16 hospitals since the start of the conflicts due to staff safety concerns as well as a shortage of hospital supplies, consumables, and medication. There has also been a gradual waning of donor support and resources allocated to address protracted crises and emergencies worldwide Sudan receives very little funding from donor organizations to maintain its healthcare system, which worsens the nation's general public health architecture. This makes the country vulnerable to serious challenges like disease outbreaks, starvation, infectious diseases, deteriorating health infrastructure, and mental health issues. To successfully reduce the severity of negative impacts on public health, the crisis must be ceased and facilities reopened. An emergency disease surveillance system for infectious diseases should be established, women and child health should be prioritized, and mental health awareness programs and services should be implemented. The global community must support the efforts to mitigate the devastating effects of this crisis. This article aims to highlight the critical impact of the recent war on Sudan's healthcare, advocating for urgent measures, including facility reopening, disease surveillance, and global support to mitigate devastating consequences.
Monitoring the mean of autocorrelated data with long memory from cable production using one‐sided runs rules schemes with ARFIMA (1,d,1) model
Authors: Babatunde Oluwagbenga Tobi , Khoo Michael B. C. , Saha Sajal , Godase Dadasaheb G. 
Published: January 2024

AbstractClassical control charts were developed with the assumption that the quality characteristics being monitored are independent. However, observations from several time‐dependent processes, such as industrial or manufacturing, are bound to be autocorrelated such that their autocorrelations decay gradually (long memory) rather than exponentially (short memory). Runs rules monitoring schemes have been proposed in Statistical Process Control literature to monitor processes in the presence of autocorrelation by incorporating the autoregressive integrated moving average (ARIMA) class of models which can only handle autocorrelation with a short memory. This paper therefore incorporates the autoregressive fractionally integrated moving average (ARFIMA (1,d,1)) model into four one‐sided runs rules schemes to monitor the mean of an autocorrelated process with long memory. The performance of these four one‐sided schemes was assessed using average run length (ARL) and expected ARL (EARL) metrics. Based on the ARL and EARL of the improved runs rules (IRR) schemes, the IRR5‐of‐5 and IRR2‐of‐7 were found to issue an out‐of‐control signal faster than the corresponding standard runs rules (RR) schemes, RR5‐of‐5 and RR2‐of‐7, respectively. Also, the four one‐sided schemes IRR5‐of‐5, IRR2‐of‐7, RR5‐of‐5, and RR2‐of‐7 in their steady state condition perform better than their corresponding zero state condition. We further observed that as the fractional parameter d increases, the detection ability of the monitoring schemes reduces. The application of the four one‐sided schemes was demonstrated on the diameter of cable production.
Ni‐Catalyzed/mediated C−X (X=N, O, S) Bond Formation Chelation‐Assisted by Bidentate Directing Groups
Authors: Xu Peng , Zhao Shengxian 
Published: January 2024

AbstractRecently, transition‐metal‐catalyzed C−H functionalization has attracted significant attention due to its potential applications in different fields. Among different metals, nickel is regarded as a more sustainable 3d‐transition metal, which has been widely explored. Therefore, this review focuses on the recent advances in the field of nickel‐catalyzed C−H functionalization assisted with bidentate directing groups (DGs) to construct C−X (N, S, O) bond. The latest advancement in nickel catalysed C−X (N, S, O) bond are reviewed and covers literatures from 2015–2022. In addition, the substrate scope and limitations as well as partial mechanism are discussed.
Improvements in stress among Latinas participating in a randomized controlled trial of technology‐supported physical activity interventions
Authors: Pekmezi Dori , Dunsiger Shira , Benitez Tanya , Larsen Britta , Vasconez Andrea Mendoza , Marcus Bess 
Published: January 2024

AbstractHigh levels of stress and inactivity likely contribute to chronic disease disparities among Latinas in the U.S. and call for intervention. To inform such efforts, the current study examined the relationships among changes (over time) in physical activity, stress, and related cardiometabolic biomarkers among sedentary (mostly) first generation Latinas. Data are taken from a randomized controlled trial (N = 199 Latinas) of two home‐based physical activity interventions (Original vs. theory‐ and technology‐ Enhanced versions). Physical activity and perceived stress were assessed at baseline and 6 and 12 months. Blood draws occurred at baseline and 6 months in a random subsample (N = 153). The participants were underactive (<60/min week of moderate‐to‐vigorous physical activity) Mexican American (89%) women with moderate perceived stress scores (M = 21.49, SD = 8.55, range = 0–40) and excess weight (M BMI = 30.6) at baseline. Overall, participants reported decreases in stress after 6 months enroled in the physical activity programs. The odds of a reduction in perceived stress were 11% higher among Enhanced versus Original Intervention participants (OR = 1.11, 95% CI: 1.05–2.27). Those who met physical activity guidelines were significantly more likely to report reductions in perceived stress over 6 months (OR = 1.92, 95% CI: 1.08–4.16). Furthermore, those who reported reductions in perceived stress over 6 months reported significantly more moderate‐to‐vigorous physical activity at 12 months (+69 min/week, SE = 27.98, p = 0.01) compared to those who did not. Greater reductions in perceived stress over 6 months were associated with greater improvements in cardiometabolic biomarkers (HbA1c, triglycerides, p's < 0.05). These results support a bidirectional relationship between improvements in stress and physical activity among Latinas. Future implications include using physical activity to address stress management and health disparities in this community.
Tip‐based Lithography with a Sacrificial Layer
Authors: Jo Jeong‐Sik , Lee Jinho , Choi Chiwon , Jang Jae‐Won 
Published: January 2024

AbstractThe fabrication of a highly controlled gold (Au) nanohole (NH) array via tip‐based lithography is improved by incorporating a sacrificial layer—a tip‐crash buffer layer. This inclusion mitigates scratches during the nano‐indentation process by employing a 300 nm thick poly(methyl methacrylate) layer as a sacrificial layer on top of the Au film. Such a precaution ensures minimal scratches on the Au film, facilitating the creation of sub‐50 nm Au NHs with a 15 nm gap between the Au NHs. The precision of this method exceeds that of fabricating Au NHs without a sacrificial layer. Demonstrating its versatility, this Au NH array is utilized in two distinct applications: as a dry etching mask to form a molybdenum disulfide hole array and as a catalyst in metal‐assisted chemical etching, resulting in conical‐shaped silicon nanostructures. Additionally, a significant electric field is generated when Au nanoparticles (NPs) are placed within the Au NHs. This effect arises from coupling electromagnetic waves, concentrated by the Au NHs and amplified by the Au NPs. A notable result of this configuration is the enhancement factor of surface‐enhanced Raman scattering, which is an order of magnitude greater than that observed with just Au NHs and Au NPs alone.
Crown Ether Electrolyte Additive Enables High‐Rate and Stable Polyviologen Cathode Material for Chloride Ion Batteries
Authors: Xue Zhiyang , Chen Yun , Xu Kangjie , Miao Yingchun , Zhao Xiangyu 
Published: January 2024

AbstractA variety of inorganic and inorganic cathode materials for chloride ion storage are reported. However, their application in chloride ion batteries (CIB) is hindered by poor rate capability and cycling stability. Herein, an organic poly(butyl viologen dichloride) (PBVCl2) cathode material with significantly enhanced rate and cycling performance in the CIB is achieved using a crown ether (18‐Crown‐6) additive in the tributylmethylammonium chloride‐based electrolyte. The as‐prepared PBVCl2 cathodes exhibit impressive capacity increases from 149.4 to 179.1 mAh g−1 at 0.1 C and from 57.8 to 111.9 mAh g−1 at 10 C, demonstrating the best rate performance with the highest energy density among those of various reported cathodes for CIBs. This impressive performance improvement is a result of the great boosts in charge transfer, ion transport, and interface stability of the battery by the use of 18‐Crown‐6, which also contributes to a more than twofold increase in capacity retention after 120 cycles. The electrode reaction mechanism of the CIB based on highly reversible chloride ion transfer is revealed by Fourier transform infrared spectroscopy and X‐ray photoelectron spectroscopy.
Language teacher identities and identity tensions of early career English teachers
Authors: Taşdemir Hanife , Seferoğlu Gölge 
Published: January 2024

AbstractIn this article, we explore the tensions early career English teachers experience in their language teacher identities (LTIs). To this effect, we conducted semi‐structured interviews with three early career English teachers at Turkish public schools. The findings showed that the teachers experienced tensions with their roles as teachers, language competency, and structural and relational aspects in their contexts. Devising and employing coping strategies in navigating challenges, the teachers developed their own ways to deal with various identity tensions. The findings of this study conclude that (i) maintaining LTIs is emotionally complex, (ii) LTIs happen in social practice, and (iii) meso and macro contexts supersede ideals causing dilemmas, conflicts, and tensions in LTIs. Drawing on the findings, we argue that teachers' emotional needs and identity tensions should be provided for through institutional and interrelational support systems so that teachers can manage tensions and emotionality as potential in their identities.
Constraining the Higgs trilinear coupling from an SU(2) quadruplet with bounded-from-below conditions
Authors: Kannike K. 
Published: January 2024

AbstractIntegrating out a heavy scalar can cause the Higgs trilinear coupling to deviate from its Standard Model value: a good example is provided by an SU(2) quadruplet. Constraints on the full theory, however, can limit the size of the deviation. We show that the bounded-from-below conditions for the Standard Model extended by an SU(2) quadruplet strongly constrain the ℤ2-breaking Higgs portal and can bound the Higgs trilinear coupling close to its Standard Model value. For TeV-scale quadruplet masses in models with custodial symmetry violation, these constraints can be a few times stronger than constraints from electroweak precision measurements. For the custodial quadruplet, these are the strongest theoretical constraints available.
Computational Mirror Symmetry
Authors: Demirtas Mehmet , Kim Manki , McAllister Liam , Moritz Jakob , Rios-Tascon Andres 
Published: January 2024

Abstract
We present an efficient algorithm for computing the prepotential in compactifications of type II string theory on mirror pairs of Calabi-Yau threefolds in toric varieties. Applying this method, we exhibit the first systematic computation of genus-zero Gopakumar-Vafa invariants in compact threefolds with many moduli, including examples with up to 491 vector multiplets.
Investigation of thermomechanical properties of solid rocket propellant used in multi-barrel rocket systems
Authors: Cegla Marcin , Czerwinska Magdalena , Kasprzak Piotr 
Published: January 2024

AbstractThe effectiveness of multi-barrel rocket systems on today’s battlefields is strongly dependent on the reliability of operation and, hence, proper action of all components, especially rockets and propellants. Therefore, the properties of the solid rocket propellants used in the rocket motors must be determined with an efficient and reliable tool providing repeatable results. The article presents the results of a thermomechanical analysis of solid double-base rocket propellant used in multi-barrel rocket systems. One of the recommended methods for testing solid rocket propellants is dynamic mechanical analysis. Mechanical properties such as the dynamic storage modulus $$(E^\prime )$$

(

E
′

)

, the dynamic loss modulus $$(E^{\prime \prime }),$$

(

E
″

)
,

and the tangent tan$$(\delta )$$

(
δ
)

of the phase shift angle $$(E^{\prime \prime }/E^\prime )$$

(

E
″

/

E
′

)

were measured with the use of the TA Instruments DMA Q 800 device, in a temperature range of − 100 to $$+$$
+
100 $$^\circ $$

∘

C with the use of different frequencies of applied force and heating rates. Special attention was devoted to determining the glass transition temperature following the STANAG 4540 standardization agreement, as well as the influence of testing parameters on the obtained experimental results. Dynamic mechanical analysis has proven to be an effective method for the evaluation of key properties influencing rocket motor behavior.
Linear models with time-varying parameters: a comparison of different approaches
Authors: Lucchetti Riccardo “Jack” , Valentini Francesco 
Published: January 2024

AbstractEstimation of linear models with time-varying parameters can be accomplished in a variety of ways, each making different assumptions, with varying degrees of accuracy and computational complexity. In this paper, we compare different packages by means of simulated and real data focusing on both statistical and computational aspects. Our findings show that all the estimators provide similar results under ideal conditions, but the practitioner’s choice could be far from obvious.
Establishing performance metrics for quantitative non-targeted analysis: a demonstration using per- and polyfluoroalkyl substances
Authors: Pu Shirley , McCord James P. , Bangma Jacqueline , Sobus Jon R. 
Published: January 2024

AbstractNon-targeted analysis (NTA) is an increasingly popular technique for characterizing undefined chemical analytes. Generating quantitative NTA (qNTA) concentration estimates requires the use of training data from calibration “surrogates,” which can yield diminished predictive performance relative to targeted analysis. To evaluate performance differences between targeted and qNTA approaches, we defined new metrics that convey predictive accuracy, uncertainty (using 95% inverse confidence intervals), and reliability (the extent to which confidence intervals contain true values). We calculated and examined these newly defined metrics across five quantitative approaches applied to a mixture of 29 per- and polyfluoroalkyl substances (PFAS). The quantitative approaches spanned a traditional targeted design using chemical-specific calibration curves to a generalizable qNTA design using bootstrap-sampled calibration values from “global” chemical surrogates. As expected, the targeted approaches performed best, with major benefits realized from matched calibration curves and internal standard correction. In comparison to the benchmark targeted approach, the most generalizable qNTA approach (using “global” surrogates) showed a decrease in accuracy by a factor of ~4, an increase in uncertainty by a factor of ~1000, and a decrease in reliability by ~5%, on average. Using “expert-selected” surrogates (n = 3) instead of “global” surrogates (n = 25) for qNTA yielded improvements in predictive accuracy (by ~1.5×) and uncertainty (by ~70×) but at the cost of further-reduced reliability (by ~5%). Overall, our results illustrate the utility of qNTA approaches for a subclass of emerging contaminants and present a framework on which to develop new approaches for more complex use cases.
Graphical Abstract
Selenium speciation studies in cancer patients to evaluate the responses of biomarkers of selenium status to different selenium compounds
Authors: del Castillo Busto M. Estela , Ward-Deitrich Christian , Evans Stephen O. , Rayman Margaret P. , Jameson Michael B. , Goenaga-Infante Heidi 
Published: January 2024

Abstract
This work presents the first systematic comparison of selenium (Se) speciation in plasma from cancer patients treated orally with three Se compounds (sodium selenite, SS; L-selenomethionine, SeMet; or Se-methylselenocysteine, MSC) at 400 µg/day for 28 days. The primary goal was to investigate how these chemical forms of Se affect the plasma Se distribution, aiming to identify the most effective Se compound for optimal selenoprotein expression. This was achieved using methodology based on HPLC-ICP-MS after sample preparation/fractionation approaches. Measurements of total Se in plasma samples collected before and after 4 weeks of treatment showed that median total Se levels increased significantly from 89.6 to 126.4 µg kg−1 Se (p < 0.001), particularly when SeMet was administered (190.4 µg kg−1 Se). Speciation studies showed that the most critical differences between treated and baseline samples were seen for selenoprotein P (SELENOP) and selenoalbumin after administration with MSC (p = 5.8 × 10−4) and SeMet (p = 6.8 × 10−5), respectively. Notably, selenosugar-1 was detected in all low-molecular-weight plasma fractions following treatment, particularly with MSC. Two different chromatographic approaches and spiking experiments demonstrated that about 45% of that increase in SELENOP levels (to ~ 8.8 mg L−1) with SeMet is likely due to the non-specific incorporation of SeMet into the SELENOP affinity fraction. To the authors’ knowledge, this has not been reported to date. Therefore, SELENOP is probably part of both the regulated (55%) and non-regulated (45%) Se pools after SeMet administration, whereas SS and MSC mainly contribute to the regulated one.

Graphical abstract
Updated systematic review and network meta-analysis of first-line treatments for metastatic renal cell carcinoma with extended follow-up data
Authors: Yanagisawa Takafumi , Mori Keiichiro , Matsukawa Akihiro , Kawada Tatsushi , Katayama Satoshi , Bekku Kensuke , Laukhtina Ekaterina , Rajwa Pawel , Quhal Fahad , Pradere Benjamin , Fukuokaya Wataru , Iwatani Kosuke , Murakami Masaya , Bensalah Karim , Grünwald Viktor , Schmidinger Manuela , Shariat Shahrokh F. , Kimura Takahiro 
Published: January 2024

AbstractImmune checkpoint inhibitor (ICI)-based combination therapies are the recommended first-line treatment for metastatic renal cell carcinoma (mRCC). However, no head-to-head phase-3 randomized controlled trials (RCTs) have compared the efficacy of different ICI-based combination therapies. Here, we compared the efficacy of various first-line ICI-based combination therapies in patients with mRCC using updated survival data from phase-3 RCTs. Three databases were searched in June 2023 for RCTs that analyzed oncologic outcomes in mRCC patients treated with ICI-based combination therapies as first-line treatment. A network meta-analysis compared outcomes including overall survival (OS), progression-free survival (PFS), objective response rate (ORR), and complete response (CR) rate. Subgroup analyses were based on the International mRCC Database Consortium risk classification. The treatment ranking analysis of the entire cohort showed that nivolumab + cabozantinib (81%) had the highest likelihood of improving OS, followed by nivolumab + ipilimumab (75%); pembrolizumab + lenvatinib had the highest likelihood of improving PFS (99%), ORR (97%), and CR (86%). These results remained valid even when the analysis was limited to patients with intermediate/poor risk, except that nivolumab + ipilimumab had the highest likelihood of achieving CR (100%). Further, OS benefits of ICI doublets were not inferior to those of ICI + tyrosine kinase inhibitor combinations. Recommendation of combination therapies with ICIs and/or tyrosine kinase inhibitors based on survival benefits and patient pretreatment risk classification will help advance personalized medicine for mRCC.