bluuebunny/crossref_metadata_2025_split huggingface dataset:
Financially supported nonprofits and IRS Form 990 expense reporting
Authors: Allen Arthur , Corradino Laurie , McAllister Brian 
Published: January 2024

PurposeThe authors examine whether limitations in Form 990 result in zero or understated fundraising and administrative expenses for organizations supported by related organizations. Form 990 does not consolidate financial information of legally separate related organizations, resulting in fundraising and administrative expenses being reported by supporting organizations but not by the supported organization.Design/methodology/approachThe authors use the IRS Statistics of Income Sample Data Files and compare charities receiving support from related organizations (supported) to non-supported charities.FindingsThe authors find evidence that supported organizations are likely to report zero or understated fundraising expenses and zero administrative expenses. Those receiving related donations are more likely to have zero or understated fundraising expense while those receiving related compensation are more likely to have zero and understated fundraising and administrative expenses. The authors also find evidence that supported organizations receiving greater amounts of related donations and related compensation are also more likely to report zero and understated fundraising expenses as well as zero administrative expenses while greater amounts of related compensation are also associated with understated administrative expense.Practical implicationsSince donors and other stakeholders use Form 990 to evaluate nonprofits, its unconsolidated nature could result in a lack of comparability across organizations and misinformed resource allocation (e.g. donation) decisions. The results also have implications for researchers who use zero and understated fundraising and administrative expenses as proxies for low quality reporting or interpret them as data errors.Originality/valueThe paper examines the extent to which zero or understated fundraising expense reporting (i.e. the fundraising expense puzzle) is associated with supported organizations receiving financial support from related organizations. The authors also expand their examination to zero and understated administrative expenses.
Leading collaborative change amid a crisis: a framework to liberate a team’s leadership skills and promote sales performance
Authors: Garrido Sol 
Published: January 2024

PurposeThis study aims to introduce an alternative model, “volatility, uncertainty, complexity and ambiguity (VUCA), Virtue and Vice” (3V’s), to unleash leadership skills, promote organisational collaborative change and impact sales performance during an unprecedented crisis.Design/methodology/approachThe methodology outlines action research based on the 3V’s model and its application in an international business-to-business sales organisation during Covid-19. It explores alternative paths informed by play-at-work and Plato’s philosophy applied to work-based-learning. Each action/iteration adds to the model, which becomes more likely appropriate for various situations.FindingsThe 3V’s boosted change implementation and improved sales performance. The 3V’s conceptualised an invitation to immerse oneself in the constant “river of change” (VUCA) and a means of understanding the role of leadership in navigating this change by embracing simple rules: searching for justice (Virtue) and overcoming the barrier of public opinion (Vice).Research limitations/implicationsThe 3V’s model is grounded in leadership literature and a sole application, providing real international data relevant to organisations and leaders. This has yet to be evaluated further.Practical implications3V’s can enhance the understanding of a leading collaborative change and re-frame team dynamics in post-pandemic times for the broader public.Social implicationsThe approach advocated is a practice of “swimming alongside the team”, which should enable empowerment and collaboration rather than a top-down direction. Focussing on leaders who are moral people, this approach becomes a differentiator in a digital world.Originality/valueThis study examines Plato’s philosophy, play-at-work and other leadership theories in a model which prepares organisations to respond to crisis by providing the ability to reflect on human aspects and straightforward, transferable skills.
Predictive simulation of construction site noise emissions from heavy equipment
Authors: Babazadeh Nasim , Teizer Jochen , Bargstädt Hans-Joachim , Melzner Jürgen 
Published: January 2024

PurposeConstruction activities conducted in urban areas are often a source of significant noise disturbances, which cause psychological and health issues for residents as well as long-term auditory impairments for construction workers. The limited effectiveness of passive noise control measures due to the close proximity of the construction site to surrounding neighborhoods often results in complaints and eventually lawsuits. These can then lead to delays and cost overruns for the construction projects.Design/methodology/approachThe paper proposes a novel approach to integrating construction noise as an additional dimension into scheduling construction works. To achieve this, a building information model, including the three-dimensional construction site layout object geometry, resource allocation and schedule information, is utilized. The developed method explores further project data that are typically available, such as the assigned equipment to a task, its precise location, and the estimated duration of noisy tasks. This results in a noise prediction model by using noise mapping techniques and suggesting less noisy alternative ways of construction. Finally, noise data obtained from sensors in a case study contribute real values for validating the proposed approach, which can be used later to suggest solutions for noise mitigation.FindingsThe results of this study indicate that the proposed approach can accurately predict construction noise given a few available parameters from digital project planning and sensors installed on a construction site. Proactively integrating construction noise control measures into the planning process has benefits for both residents and construction managers, as it reduces construction noise-related disturbances, prevents unexpected legal issues and ensures the health and well-being of the workforce.Originality/valueWhile previous research has concentrated on real-time data collection using sensors, a more effective solution would also involve addressing and mitigating construction noise during the pre-construction work planning phase.
Can a change in the leadership of a populist radical right party be traced among voters? The case of the Finns Party
Authors: Söderlund Peter , Grönlund Kimmo 
Published: January 2024

AbstractWhat happens to the electorate of a populist radical right party when the party splits? Finland provides an excellent case for an analysis of this nature. In 2017, the Finns Party split due to an internal rift. Party leadership was taken over by members of the party's anti‐immigrant faction, who, in the election of 2019, succeeded in replicating the party's previous electoral successes in 2011 and 2015. At the same time, the moderate faction that split from the party was wiped out in the election. In the election of 2023, the party gained yet another victory. Using the Finnish National Election Studies (2011, 2015, 2019 and 2023), we examine whether the party's transformation to a more anti‐immigrant populist radical right party is reflected in the policy positions and sociodemographic composition of the party's electorate. Our findings show that the electorate came to reflect the change in leadership after the party split. Furthermore, we are able to demonstrate that the pattern prevails in the newest election of 2023 under the leadership of Riikka Purra.
Learning from errors versus explicit instruction in preparation for a test that counts
Authors: Metcalfe Janet , Xu Judy , Vuorre Matti , Siegler Robert , Wiliam Dylan , Bjork Robert A. 
Published: January 2024

AbstractBackgroundAlthough the generation of errors has been thought, traditionally, to impair learning, recent studies indicate that, under particular feedback conditions, the commission of errors may have a beneficial effect.AimsThis study investigates the teaching strategies that facilitate learning from errors.Materials and MethodsThis 2‐year study, involving two cohorts of ~88 students each, contrasted a learning‐from‐errors (LFE) with an explicit instruction (EI) teaching strategy in a multi‐session implementation directed at improving student performance on the high‐stakes New York State Algebra 1 Regents examination. In the LFE condition, instead of receiving instruction on 4 sessions, students took mini‐tests. Their errors were isolated to become the focus of 4 teacher‐guided feedback sessions. In the EI condition, teachers explicitly taught the mathematical material for all 8 sessions.ResultsTeacher time‐on in the LFE condition produced a higher rate of learning than did teacher time‐on in the EI condition. The learning benefit in the LFE condition was, however, inconsistent across teachers. Second‐by‐second analyses of classroom activities, directed at isolating learning‐relevant differences in teaching style revealed that a highly interactive mode of engaging the students in understanding their errors was more conducive to learning than was teaching directed at getting to the correct solution, either by lecturing about corrections or by interaction focused on corrections.ConclusionThese results indicate that engaging the students interactively to focus on errors, and the reasons for them, facilitates productive failure and learning from errors.
Understanding the pathogenic mechanisms and therapeutic effects in neurocysticercosis
Authors: Castillo Gino , Fustamante Lizbeth , Delgado‐Kamiche Ana D. , Camen‐Orozco Rogger P. , Clark Taryn , Bernal Edson , Morales‐Alvarez Jemima , Ferrufino Maria , Mamani‐Palomino Javier , Bustos Javier A. , Garcia Hector H. , Gavidia Cesar M. , Gilman Robert H. , Verastegui Manuela ,   Cysticercosis Working Group in Peru
Published: January 2024

AbstractDespite being a leading cause of acquired seizures in endemic regions, the pathological mechanisms of neurocysticercosis are still poorly understood. This study aims to investigate the impact of anthelmintic treatment on neuropathological features in a rat model of neurocysticercosis. Rats were intracranially infected with Taenia solium oncospheres and treated with albendazole + praziquantel (ABZ), oxfendazole + praziquantel (OXF), or untreated placebo (UT) for 7 days. Following the last dose of treatment, brain tissues were evaluated at 24 h and 2 months. We performed neuropathological assessment for cyst damage, perilesional brain inflammation, presence of axonal spheroids, and spongy changes. Both treatments showed comparable efficacy in cyst damage and inflammation. The presence of spongy change correlated with spheroids counts and were not affected by anthelmintic treatment. Compared to white matter, gray matter showed greater spongy change (91.7% vs. 21.4%, p < 0.0001), higher spheroids count (45.2 vs. 0.2, p = 0.0001), and increased inflammation (72.0% vs. 21.4%, p = 0.003). In this rat model, anthelmintic treatment destroyed brain parasitic cysts at the cost of local inflammation similar to what is described in human neurocysticercosis. Axonal spheroids and spongy changes as markers of damage were topographically correlated, and not affected by anthelmintic treatment.
Behandlung der Acne fulminans mit Tumornekrosefaktor‐α‐Inhibitoren – eine Übersicht klinischer Fälle und der Literatur
Authors: Taudorf Elisabeth Hjardem , Jensen Mikkel Bak , Bouazzi Dorra , Sand Carsten , Thomsen Simon Francis , Jemec Gregor Borut Ernst , Saunte Ditte Marie Lindhardt 
Published: January 2024

ZusammenfassungAcne fulminans (AF) ist eine seltene, schwerwiegende, plötzlich auftretende und lang andauernde Hauterkrankung, die Vernarbungen im Gesicht und am Körper verursacht. Die Standardbehandlung mit langfristiger Verabreichung einer Kombination aus Isotretinoin und Prednisolon reicht nicht immer aus und kann unerwünschten Wirkungen haben. Es gibt daher einen ungedeckten Bedarf an besseren Therapien. Fallberichte lassen darauf schließen, dass Tumornekrosefaktor‐α (TNF‐α)‐Inhibitoren eine Rolle bei der Behandlung von AF spielen könnten. In einer 3 Jahre abdeckenden retrospektiven Datenerhebung aus zwei dermatologischen Zentren sowie einer Literaturübersicht klinischer Fälle von Acne fulminans, die mit Anti‐TNF‐α‐Therapie behandelt wurden, konnten drei klinische Fälle und zwölf Literaturfälle ermittelt werden. Insgesamt wurden fünf verschiedene TNF‐α‐Inhibitoren eingesetzt, am häufigsten Adalimumab. Klinisches Ansprechen wurde nach 1 Monat bei 2/3 (67%) der klinischen Fälle beziehungsweise 5/12 (42%) der Literaturfälle beobachtet. Nach einer medianen Dauer von 3–7 Monaten war die Behandlung bei 2/3 (67%) und 11/12 (92%) der Betroffenen erfolgreich. Alle berichteten unerwünschten Wirkungen waren leicht und reversibel. Die Anti‐TNF‐α‐Behandlung kann zu schneller Verbesserung bei Patienten mit AF führen, wenn die Erstbehandlung mit Isotretinoin und Prednisolon versagt. Allerdings fehlen randomisierte, kontrollierte Studien, und die exakte Dosierung sowie der exakte Zeitablauf müssen vor der klinischen Umsetzung genauer geprüft werden.
Prevalence of dental, oral, and maxillofacial traumatic injuries among domestic violence victims: A systematic review and meta‐analysis
Authors: de Souza Cantão Ana Beatriz Carvalho , da Silva Lima Thiago César , Fernandes Marina Izabelle Avelar Pires , Nagendrababu Venkateshbabu , Bastos Juliana Vilela , Levin Liran 
Published: January 2024

AbstractBackground/AimsDomestic violence (DV) encompasses a series of abusive behaviors, perpetrated in a family environment, against individuals of all ages and genders. Injuries to the head, neck, and face are frequent findings among victims of abuse, negatively impacting their quality of life. Although oral and maxillofacial injuries (OMFI) and traumatic dental injuries (TDI) are commonly diagnosed among DV victims, their prevalence is still unknown. This systematic review was aimed to assess the prevalence of OMFI and TDI among victims of DV.MethodsThe protocol of the review was registered in PROSPERO (CRD42023424235). Literature searches were performed in eight electronic databases, up to August 7th, 2023. Observational studies published in the Latin‐roman alphabet and reporting the prevalence of OMFI and/or TDI were included. The Joanna Briggs Institute's critical appraisal tool, checklist for prevalence studies, was used for quality assessment. Results were presented as qualitative and quantitative syntheses.ResultsSeventeen studies, totaling 12,375 victims of domestic violence, were included. Meta‐analyses showed an overall prevalence of 29% (95% CI: 15%–48%, I2 = 99%) and 4% (95% CI: 1%–10%, I2 = 98%) for OMFI and TDI, respectively. Higher pooled prevalence for OMFI (41%, 95% CI: 13%–46%, I2 = 99%) was demonstrated in samples with only women. OMFI was less prevalent (20%) among DV victims under 18, while TDI was lower among adults (1%). Hospital samples presented higher pooled prevalence of OMFI (32%), and forensic data from fatal victims presented higher prevalence of TDI (8%).ConclusionThe overall prevalence of OMFI and TDI in DV victims was 29% and 4%, respectively. Women victims of DV presented higher rates of OFMI (41%) and TDI (6%).
Vitamin C compounds mixture prevents skin barrier alterations and inflammatory responses upon real life multi pollutant exposure
Authors: Ferrara Francesca , Pecorelli Alessandra , Pambianchi Erika , White Stacy , Choudhary Hina , Casoni Alice , Valacchi Giuseppe 
Published: January 2024

AbstractCutaneous tissues is among the main target of outdoor stressors such as ozone (O3), particulate matter (PM), and ultraviolet radiation (UV) all involved in inducing extrinsic skin aging. Only a few reports have studied the multipollutant interaction and its effect on skin damage. In the present work, we intended to evaluate the ability of pollutants such as O3 and PM to further aggravate cutaneous UV damage. In addition, the preventive properties of a cosmeceutical formulation mixture (AOX mix) containing 15% vitamin C (L‐ascorbic acid), 1% vitamin E (α‐tocopherol) and 0.5% ferulic acid was also investigated. Skin explants obtained from three different subjects were exposed to 200 mJ UV light, 0.25 ppm O3 for 2 h, and 30 min of diesel engine exhaust (DEE), alone or in combination for 4 days (time point D1 and D4). The results showed a clear additive effect of O3 and DEE in combination with UV in terms of keratin 10, Desmocollin and Claudin loss. In addition, the multipollutant exposure significantly induced the inflammatory response measured as NLRP1/ASC co‐localization suggesting the activation of the inflammasome machinery. Finally, the loss of Aquaporin3 was also affected by the combined outdoor stressors. Furthermore, daily topical pre‐treatment with the AOX Mix significantly prevented the cutaneous changes induced by the multipollutants. In conclusion, this study is among the first to investigate the combined effects of three of the most harmful outdoor stressors on human skin and confirms that daily topical of an antioxidant application may prevent pollution‐induced skin damage.
Extracellular vimentin as a modulator of the immune response and an important player during infectious diseases
Authors: Suprewicz Łukasz , Zakrzewska Magdalena , Okła Sławomir , Głuszek Katarzyna , Sadzyńska Alicja , Deptuła Piotr , Fiedoruk Krzysztof , Bucki Robert 
Published: January 2024

AbstractVimentin, an intermediate filament protein primarily recognized for its intracellular role in maintaining cellular structure, has recently garnered increased attention and emerged as a pivotal extracellular player in immune regulation and host–pathogen interactions. While the functions of extracellular vimentin were initially overshadowed by its cytoskeletal role, accumulating evidence now highlights its significance in diverse physiological and pathological events. This review explores the multifaceted role of extracellular vimentin in modulating immune responses and orchestrating interactions between host cells and pathogens. It delves into the mechanisms underlying vimentin's release into the extracellular milieu, elucidating its unconventional secretion pathways and identifying critical molecular triggers. In addition, the future perspectives of using extracellular vimentin in diagnostics and as a target protein in the treatment of diseases are discussed.
Clinicoradiologic features of ameloblastomas: A single‐centre study of 155 cases
Authors: Smit Chané , Robinson Liam , Ker‐Fox Jason , Fonseca Felipe Paiva , van Heerden Willie F. P. , Uys André 
Published: January 2024

AbstractBackgroundThe purpose of the current study was to report on the clinical presentation and radiologic features of 155 cases of ameloblastoma (AB), representing a detailed, large, single‐centre radiologic study.MethodsHistologically confirmed cases were reviewed over 11 years. Demographic and clinical data were retrieved from the patient's records. Radiologic information was analysed from available radiographs. The radiologic features of ABs were assessed according to the mean age of presentation and the mean duration of the lesion. The distinguishing radiologic features between adults/children and sex were also evaluated.ResultsA statistically significant correlation existed between loss of border demarcation and advanced mean age. Multilocular lesions were markedly more common in adults compared to children. Multilocular ABs were associated with increased lesion duration and advanced mean age. Radiologic signs of reactive bony changes associated with the tumour presented at the highest mean duration of all bony effects. Bony expansion and cortical destruction were statistically correlated with lesion duration. Tooth impaction was more common in children. Some mandibular lesions reached a significant size, resulting in impingement of the maxillary sinus, zygoma, orbit and pterygoid plates.ConclusionDue to unfortunate healthcare access constraints, ABs grow to significant sizes and exhibit features not often reported in the literature. The findings of this analysis highlighted the radiologic features of ABs expressed through the mean age and duration of the lesion. This emphasises the significance of timely management of these lesions.
Decision aids for promoting shared decision‐making: A review of systematic reviews
Authors: Park Myonghwa , Doan Thao Thi‐Thu , Jung Jihye , Giap Thi‐Thanh‐Tinh , Kim Jinju 
Published: January 2024

AbstractIn the context of shared decision‐making (SDM), experts have advocated the use of validated decision aids (DAs) as valuable tools for facilitating SDM in various healthcare scenarios. This comprehensive review attempts to analyze a vast corpus of DA research by performing thorough searches across four prominent databases (PubMed, CINAHL, Embase, and Web of Science). Independent reviewers selected relevant reviews, extracted data, and assessed review quality using the AMSTAR II tool. A total of 34 systematic reviews were identified and evaluated in this review, encompassing a wide range of outcomes associated with using DAs. These outcomes include patient knowledge, patient involvement in SDM, decision conflict, decision regret, satisfaction, and adherence. In addition, DAs positively affect healthcare provider outcomes by increasing satisfaction, reducing decision conflicts, and lengthening clinical consultations. This review highlights the need for additional research in specific contexts such as long‐term care, mental health, and reproductive health to better understand the benefits and challenges of implementing DAs in these settings. Such research can contribute to the improvement of SDM practices and patient‐centered care.
Genomic basis of seed colour in quinoa inferred from variant patterns using extreme gradient boosting
Authors: Sandell Felix L. , Holzweber Thomas , Street Nathaniel R. , Dohm Juliane C. , Himmelbauer Heinz 
Published: January 2024

SummaryQuinoa is an agriculturally important crop species originally domesticated in the Andes of central South America. One of its most important phenotypic traits is seed colour. Seed colour variation is determined by contrasting abundance of betalains, a class of strong antioxidant and free radicals scavenging colour pigments only found in plants of the order Caryophyllales. However, the genetic basis for these pigments in seeds remains to be identified. Here we demonstrate the application of machine learning (extreme gradient boosting) to identify genetic variants predictive of seed colour. We show that extreme gradient boosting outperforms the classical genome‐wide association approach. We provide re‐sequencing and phenotypic data for 156 South American quinoa accessions and identify candidate genes potentially controlling betalain content in quinoa seeds. Genes identified include novel cytochrome P450 genes and known members of the betalain synthesis pathway, as well as genes annotated as being involved in seed development. Our work showcases the power of modern machine learning methods to extract biologically meaningful information from large sequencing data sets.