bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between perceived social support and mental health among Chinese college football athletes: a moderated mediation model
Authors: Liu Zongyu , Zhao Xiuhan , Zhao Liangyu , Zhang Liguo 
Published: October 2023

AbstractPrevious researches have confirmed that perceived social support has a profound effect on individuals’ mental health. However, the effects and potential mechanisms of perceived social support on mental health of college athletes are still largely unknown, especially during and after the COVID-19 pandemic. Thus, the aim of this study was to explore the relationship between perceived social support and mental health in college football athletes, and to evaluate whether hopelessness and psychological pressure affected this relationship. A sample of 672 Chinese college football athletes (37.9% girls; Mage = 20.43 years; SDage = 1.68) were investigated with the Perceived Social Support Scale (PSSS), the Kessler Psychological Distress Scale (K10), the Beck Hopelessness Scale (BHS) and the Perceived Stress Scale (PSS). Surveys were voluntary and anonymous. The findings revealed that, after adjusting for demographic factors, hopelessness mediated the relationship between Chinese college football athletes’ perceived social support and their mental health. Furthermore, psychological pressure moderated the negative association between perceived social support and hopelessness, and the association was stronger for them with high-level psychological pressure. These results underline the need for focused strategies in the prevention and treatment of mental health issues among Chinese college football athletes.
"Better Living with Non-memory-led Dementia": protocol for a feasibility randomised controlled trial of a web-based caregiver educational programme
Authors: Suárez-González Aida , John Amber , Brotherhood Emilie , Camic Paul M. , McKee-Jackson Roberta , Melville Mel , Sullivan Mary Pat , Tudor-Edwards Rhiannon , Windle Gill , Crutch Sebastian , Hoare Zoe , Stott Joshua ,   the Rare Dementia Support Impact team
Published: October 2023

Abstract
Background
Non-memory-led dementias such as posterior cortical atrophy (PCA), primary progressive aphasia (PPA) and behavioural variant frontotemporal dementia (bvFTD) are low prevalent and often affect individuals under the age of 65. Tailored educational and support resources for caregivers of people living with these dementia phenotypes are scarce and unevenly distributed geographically. Web-based educational programmes are emerging as promising alternatives to improve caregiver self-efficacy and well-being. Here, we present the protocol of a study aiming to assess the feasibility of a co-produced online educational programme for caregivers of people living PCA, PPA and bvFTD: the Better Living with Non-memory-led Dementia programme.

Methods
A randomised controlled feasibility trial will be conducted on a sample of 30 caregivers of people living with PCA, PPA and bvFTD. Participants will be recruited among members of the support organisation Rare Dementia Support (based at UCL in the UK). The intervention group will be given access to an 8-week co-produced web-based educational programme consisting of 6 modules addressing education about PCA, PPA and bvFTD and support strategies for the person with dementia and for the caregiver. The control group will receive treatment as usual (TAU). Feasibility will be measured through feasibility of recruitment, clinical measurement tools and acceptability. Clinical measures will be used to assess preliminary efficacy and data on completion rates, missing data and variability used to decide on measures to be included in a full-scale trial.
Allocation ratio will be 2:1 (intervention:control) stratified by diagnosis. Feasibility of recruitment and acceptability will be assessed. Clinical measures will be administered at baseline and 8-week and 3-month post-randomisation. The control group will be offered access to the intervention at the completion of data collection. Participants will be unblinded, and all measures will be self-reported online.

Discussion
Online-delivered educational programmes show potential for improving care competency of caregivers and may contribute to overcoming geographical inequalities in local provision of support services. This pilot study will inform a fully powered international trial to determine the effectiveness of Better Living with Non-memory-led Dementia.

Trial registration
This trial has been registered prospectively on the Clinical Trials Registry on 1st September 2022, registration number NCT05525377.
Au@109Pd core–shell nanoparticle conjugated to trastuzumab for the therapy of HER2+ cancers: studies on the applicability of 109Pd/109mAg in vivo generator in combined β− auger electron therapy
Authors: Gharibkandi Nasrin Abbasi , Wawrowicz Kamil , Majkowska-Pilip Agnieszka , Żelechowska-Matysiak Kinga , Wierzbicki Mateusz , Bilewicz Aleksander 
Published: October 2023

Abstract
Background
In radionuclide therapy, to enhance therapeutic efficacy, an intriguing alternative is to ensure the simultaneous implementation of low- and high-LET radiation emitted from a one radionuclide. In the present study, we introduce the concept of utilizing 109Pd (T1/2 = 13.7 h) in the form of a 109Pd/109mAg in vivo generator. In this system, 109Pd emits beta particles of medium energy, while 109mAg releases a cascade of conversion and Auger electrons. 109Pd was utilized in the form of 15 nm gold nanoparticles, which were coated with a monolayer of 109Pd. In this system, the 109Pd atoms are on the surface of the nanoparticle, while the 109mAg atoms generated in the decay reaction possess the capability for unhindered emission of Auger electrons.

Results
109Pd, obtained through neutron irradiation of natural palladium, was deposited onto 15-nm gold nanoparticles, exceeding a efficiency rate of 95%. In contrast to previously published data on in vivo generators based on chelators, where the daughter radionuclide diffuses away from the molecules, daughter radionuclide 109mAg remains on the surface of gold nanoparticles after the decay of 109Pd. To obtain a radiobioconjugate with an affinity for HER2 receptors, polyethylene glycol chains and the monoclonal antibody trastuzumab were attached to the Au@Pd nanoparticles. The synthesized bioconjugate contained an average of 9.5 trastuzumab molecules per one nanoparticle. In vitro cell studies indicated specific binding of the Au@109Pd-PEG-trastuzumab radiobioconjugate to the HER2 receptor on SKOV-3 cells, resulting in 90% internalization. Confocal images illustrated the accumulation of Au@109Pd-PEG-trastuzumab in the perinuclear area surrounding the cell nucleus. Despite the lack of nuclear localization, which is necessary to achieve an effective cytotoxic effect of Auger electrons, a substantial cytotoxic effect, significantly greater than that of pure β− and pure Auger electron emitters was observed. We hypothesize that in the studied system, the cytotoxic effect of the Auger electrons could have also occurred through the damage to the cell’s nuclear membrane by Auger electrons emitted from nanoparticles accumulated in the perinuclear area.

Conclusion
The obtained results show that trastuzumab-functionalized 109Pd-labeled nanoparticles can be suitable for the application in combined β−—Auger electron targeted radionuclide therapy. Due to both components decay (β− and conversion/Auger electrons), the 109Pd/109mAg in vivo generator presents unique potential in this field. Despite the lack of nuclear localization, which is highly required for efficient Auger electron therapy, an adequate cytotoxic effect was attained.
A rare gastrointestinal bleeding due to a cholecystoduodenal fistula: a case report
Authors: Zippi Maddalena , Toma Antonella , Hong Wandong , Fiorino Sirio , Grottesi Alfonso 
Published: October 2023

Abstract
Background
Gastrointestinal bleeding from cholecystoduodenal fistula is rare. It is usually managed surgically, although a conservative approach is reported in isolated cases.

Case presentation
A 71-year-old male patient was admitted to the emergency department (ED) presenting melena associated with severe anemia, requiring a blood transfusion. An urgent upper endoscopy showed the intestinal orifice of a cholecystoduodenal fistula. This finding was confirmed by radiological examination and laparoscopy. Cholecystectomy and simultaneous excision of the fistula were successfully performed. As a result, a diagnosis of Mirizzi syndrome type Va was also made.

Conclusion
A cholecystoduodenal fistula orifice leading to gastrointestinal bleeding is difficult to diagnose without an endoscopic examination of the upper digestive tract. Following this first diagnostic step, a comprehensive patient examination should be conducted, specifically if a history of gallbladder lithiasis has been reported.
Seasonal variation of cardiac structure and function in the elite rugby football league athlete
Authors: Forsythe Lynsey , George Keith , Papadakis Michael , Mill Nathan , Daniels Matt , Oxborough David 
Published: October 2023

Abstract
Background
Pre-participation cardiac screening (PCS) of “Super-League” rugby football league (RFL) athletes is mandatory but may be completed at any time point. The aim of this study was to assess cardiac electrical, structural and functional variation across the competitive season.

Methods
Elite, male, RFL athletes from a single Super-League club underwent cardiac evaluation using electrocardiography (ECG), 2D echocardiography and speckle tracking echocardiography (STE) at four time points across the RFL season; (1) End pre-season (ENDPRE), (2) mid-season (MIDCOMP), (3) end-season (ENDCOMP) and (4) End off-season (ENDOFF). Training loads for each time point were also determined. One-way ANOVA with post-hoc Bonferroni were used for statistical analyses.

Results
Total workload undertaken by athletes was lower at both MIDCOMP and ENDCOMP compared to ENDPRE (P < 0.001). ECG patterns were normal with training-related changes that were largely consistent across assessments. Structural data did not vary across assessment points. Standard functional data was not different across assessment points but apical rotation and twist were higher at ENDPRE (9.83˚ and 16.55˚, respectively compared to all other time points (MIDCOMP, 6.13˚ and 12.62˚; ENDCOMP, 5.84˚ and 12.12˚; ENDOFF 6.60˚ and 12.35˚).

Conclusions
Despite some seasonal variation in training load, the athletes’ ECG and cardiac structure were stable across a competitive season. Seasonal variation in left ventricular (LV) apical rotation and twist, associated with higher training loads, should be noted in the context of PCS.
Latent profiles identified from psychological test data for people convicted of sexual offences in the UK
Authors: Gillespie Steven M. , Elliott Ian A. 
Published: October 2023

BackgroundOne size does not fit all in assessment and intervention for people with convictions for sexual offences. Crime scene indicators and risk-related variables have been used to identify distinct clusters of people with convictions for sexual offences, but there is a need for more robust typologies that identify clusters based on psychologically meaningful risk factors that can be targeted in treatment.AimsTo use robust modelling techniques to identify latent profiles of people with convictions for sexual offences based on indicators of dynamic risk.MethodAdult male participants, who had been convicted for sexual offences and assessed for eligibility for the prison-based Core Sex Offender Treatment Programme delivered by His Majesty's Prison and Probation Service (UK), were randomly allocated to a test (n = 1577: 70.2%) or validation (n = 668: 29.8%) data-set. Exploratory factor analysis (EFA) was used to select measures of dynamic risk from psychological test data. EFA indicated four factors, from which six measures were selected for inclusion in latent profile analysis.ResultsFive latent profiles were identified in the test and validation data-sets. These were labelled low psychological impairment, impulsive, distorted thinker, rape preoccupied and child fantasist. Profiles varied in individual characteristics, offence histories, victim preferences and level of risk.ConclusionsOur findings should be used to guide assessment and intervention practices that are tailored to distinct psychological profiles consistent with principles of risk, need and responsivity.
MODEL OF INTEGRATION OF ARTIFICIAL INTELLIGENCE INTO THE STAFF ADAPTATION SYSTEM
Authors: Baynakova M. , Chulanova Oksana 
Published: October 2023

During the period of digital transformation, artificial intelligence technologies are actively developing and being introduced into human resource management processes. The authors consider the concept of artificial intelligence, explore the possibility of using artificial intelligence in the system of personnel adaptation. The article analyzes the main advantages and disadvantages of the ChatGPT model. A model for integrating artificial intelligence into the adaptation of company personnel is proposed.
Public health policies for children and youth with special health care needs in OECD member countries and Brazil: A scoping review protocol
Authors: Gimenes Ângela Cristina Rocha , Cury Elenir Rose Jardim 
Published: October 2023

Background
Because public health policies lay down guidelines for health promotion in specific populations, a review of policies devised for children and youth with special health care needs (CYSHCN) can reveal the actual degree of priority assigned to this population segment, while also highlighting relevant policies in this field.

Objective
To map the available evidence of public health policies for CYSHCN in member countries of the Organization for Economic Cooperation and Development (OECD) and Brazil.

Method
A scoping review protocol was developed as per the Joanna Briggs Institute (JBI) manual and the Preferred Reporting Items for Systematic Review and Meta-Analyses–Extension for Scoping Reviews (PRISMA-ScR) checklist, for application to the Web of Science (WoS), Scopus, PubMed, and Embase databases;to theLatin American and Caribbean Literature in Health Sciences (LILACS)multilingual thesaurus; and to gray literature.The review will map the principal documents (irrespective of time frame or language) addressing public health policies for CYSHCN up to 19 years old. The research protocol has been registered on the Open Science Framework platform (identifier 10.17605/OSF.IO/UW5BH:DOI).

Results and conclusion
Tables, maps, charts, and/or graphs accompanied by descriptive texts will be employed to present the results to the research question and provide answers to it. Use of both open-access software IRaMuTeQ for similitude analysis and word clouds is also planned. This protocol is expected to reveal policies that meet the specific needs of this vulnerable population segment and highlight examples of good practices or current gaps.
South Asian, Black and White ethnicity and the effect of potentially modifiable risk factors for dementia: A study in English electronic health records
Authors: Mukadam Naaheed , Marston Louise , Lewis Gemma , Mathur Rohini , Lowther Ed , Rait Greta , Livingston Gill 
Published: October 2023

Introduction
We aimed to investigate ethnic differences in the associations of potentially modifiable risk factors with dementia.

Methods
We used anonymised data from English electronic primary care records for adults aged 65 and older between 1997 and 2018. We used Cox regression to investigate main effects for each risk factor and interaction effects between each risk factor and ethnicity.

Results
We included 865,674 people with 8,479,973 person years of follow up. Hypertension, dyslipidaemia, obesity and diabetes were more common in people from minority ethnic groups than White people. The impact of hypertension, obesity, diabetes, low HDL and sleep disorders on dementia risk was increased in South Asian people compared to White people. The impact of hypertension was greater in Black compared to White people.

Discussion
Dementia prevention efforts should be targeted towards people from minority ethnic groups and tailored to risk factors of particular importance.
Psychosocial and pharmacologic interventions for problematic methamphetamine use: Findings from a scoping review of the literature
Authors: Hersi Mona , Corace Kim , Hamel Candyce , Esmaeilisaraji Leila , Rice Danielle , Dryburgh Nicole , Skidmore Becky , Garber Gary , Porath Amy , Willows Melanie , MacPherson Paul , Sproule Beth , Flores-Aranda Jorge , Dickey Chandlee , Hutton Brian 
Published: October 2023

Rationale
Methamphetamine use and related harms have risen at alarming rates. While several psychosocial and pharmacologic interventions have been described in the literature, there is uncertainty regarding the best approach for the management of methamphetamine use disorder (MUD) and problematic methamphetamine use (PMU). We conducted a scoping review of recent systematic reviews (SR), clinical practice guidelines (CPG), and primary controlled studies of psychosocial and pharmacologic treatments for MUD/PMU.

Methods
Guided by an a priori protocol, electronic database search updates (e.g., MEDLINE, Embase) were performed in February 2022. Screening was performed following a two-stage process, leveraging artificial intelligence to increase efficiency of title and abstract screening. Studies involving individuals who use methamphetamine, including key subgroups (e.g. those with mental health comorbidities; adolescents/youths; gay, bisexual, and other men who have sex with men) were sought. We examined evidence related to methamphetamine use, relapse, use of other substances, risk behaviors, mental health, harms, and retention. Figures, tables and descriptive synthesis were used to present findings from the identified literature.

Results
We identified 2 SRs, one CPG, and 54 primary studies reported in 69 publications that met our eligibility criteria. Amongst SRs, one concluded that psychostimulants had no effect on methamphetamine abstinence or treatment retention while the other reported no effect of topiramate on cravings. The CPG strongly recommended psychosocial interventions as well as self-help and family support groups for post-acute management of methamphetamine-related disorders. Amongst primary studies, many interventions were assessed by only single studies; contingency management was the therapy most commonly associated with evidence of potential effectiveness, while bupropion and modafinil were analogously the most common pharmacologic interventions. Nearly all interventions showed signs of potential benefit on at least one methamphetamine-related outcome measure.

Discussion
This scoping review provides an overview of available interventions for the treatment of MUD/PMU. As most interventions were reported by a single study, the effectiveness of available interventions remains uncertain. Primary studies with longer durations of treatment and follow-up, larger sample sizes, and of special populations are required for conclusive recommendations of best approaches for the treatment of MUD/PMU.
Effect of varied waste concrete ratios on the mechanical properties of polymer concrete
Authors: Rasheed Aliaa , Sadiq Shatha , Shaaban Aseel 
Published: October 2023

Abstract
Polymer concrete (PC) was developed at the end of the 1950s and gained popularity in the 1970s for precast parts, flimsy floor coverings, and repairs. Due to its superior performance over traditional Portland cement concrete, which offers many benefits, including mechanical properties, quick hardening, and durability. In this article, polymeric concrete was made using a mixture of sand and epoxy, and different proportions of sand were replaced with crushed concrete waste. This study found that the ideal ratio between resin and fine aggregate was 23% resin to 77% fine aggregate in terms of the total weight of the combination to get the best dispersion of fine aggregate. Waste concrete replaced 5, 10, 15, and 20% of aggregate in PC, respectively. It was further demonstrated that increased waste concrete aggregate content in PC increased the 28-day compressive strength by 7.7, 13.44, 16.8, and 18.97%, respectively; flexural strength increased by 16.68, 25.32, 37.16, and 47.71% at 28 days’ age; and direct tensile strength was higher than the reference mixture by values of 3.41, 17.21, 23.54, and 30.38% at 28 days age. The findings recommended using recycled fine aggregate on PC and suggested a 20% replacement ratio as an optimum percentage.
The Contemporary Significance of Early German Romantic Philosophy
Authors: Bowie Andrew 
Published: October 2023

Abstract
Recent interest in early German Romantic philosophy can be linked to other approaches, such as that of John Dewey, which are critical of the dominant direction of modern philosophy. The Romantics rethink the relationship between philosophy and art as a way of questioning modern philosophy’s focus on epistemology and scepticism that leads to a lack of attention to the diverse other ways in which human beings make sense of things.
Studying the Use of Earth in Early Architecture of Southwest and Central Asia
Authors: Uzdurum Melis , Schönicke Julia , Kinzel Moritz , Barański Marek Z. 
Published: October 2023

AbstractUsing case studies from Aşıklı Höyük, Çatalhöyük, Boncuklu Tarla, Göbekli Tepe (all Turkey), and Monjukli Depe (southern Turkmenistan), this study presents a framework for in-depth research on prehistoric earthen architecture in southwestern and central Asia. It demonstrates the challenges and potential for innovative and comparative studies based on interdisciplinary approaches and the use of architectural, microstratigraphic, and microarchaeological analyses. Furthermore, it sheds new light on issues related to various aspects of building continuity which is commonly recognised as a very important phenomenon in the Neolithic but could have different facets. The study attempts to discuss the reasons behind the local decisions to use and recycle specified building materials. In addition, it evaluates – in relation to particular sites – the usefulness of specific analyses for reconstruction of daily, seasonal, or annual practices. Advanced analyses of floors and fire installations, for instance, can contribute not only to the identification of indoor and outdoor surfaces but also to a better understanding of activity areas and the intensity of use within particular spaces. Variations and different combinations of mudbrick, mortar, and plaster recipes allow for insights into how earth and sediment material were used to mark collective and individual identity through the performance of a building. Recognising reused materials and features allows us to trace further the nature of prehistoric societies and local architectural dialects.