bluuebunny/crossref_metadata_2025_split huggingface dataset:
PEMBUATAN LAYANAN PENGADUAN WARGA BERBASIS WEBSITE DI KELURAHAN KALUMATA
Authors: Umasugi Mohbir , Yusuf Helmi Hi. , Hi.Adam Muhammad Darsan 
Published: September 2023

Pelayanan pengaduan warga di Kelurahan Kalumata masih manual. Warga yang mengadu harus datang ke kantor lurah untuk menjelaskan laporannya. Hal ini membuat pelayanan pengaduan belum efektif dan aksesya terbatas. Untuk menatanya agar efektif dan efesien, maka kegiatan Pengabdian Kepada Masyarakat (PKM membuat suatu sistem pelayanan warga berbasis website. Sistem ini bertujuan membantu warga dan pemerintah kelurahan dalam mengelola pengaduan warga. Metode pelaksanaan dilakukan melalui tahapan sosialisasi, peningkatan kapasitas staf kelurahan dalam penggunaan website, dan pelatihan pelaporan warga. Hasil dari kegiatan PKM Dosen yaitu telah dibuatkan sistem layanan pengaduan warga berbasis website yang langsung dioperasionalkan oleh Pemerintah Kelurahan Kalumata, Kecamatan Kota Ternate Selatan, Kota Ternate.Website ini sudah dapat digunakan warga dalam melaporkan berbagai keluhan seperti persoalan sampah, banjir, drainase, keamanan, dan ketertiban yang terjadi di lingkungan masing-masing.

The citizen complaint service in Kalumata Village is still manual. Residents who complain must come to the sub-district office to explain their reports. This makes the complaint service ineffective and access to it limited. To arrange it to be effective and efficient, the Community Service (PKM) activity created a website-based citizen service system. This system aims to assist residents and the village government in managing citizen complaints. The implementation method is carried out through socialization stages, increasing the capacity of village staff in using the website, and citizen reporting training. The result of PKM Lecturer activities is that a website-based citizen complaint service system has been created which is directly operated by the Kalumata Village Government, South Ternate City District, Ternate.Website City can be used by residents in reporting various complaints such as garbage, flooding, drainage, security, and order problems that occur in their respective neighborhoods.
PENINGKATAN PRODUKSI DAN KUALITAS SAUS TOMAT DAN SAMBAL SERTA PERANCANGAN STERILISATOR UV-C UNTUK UMKM DESA SUKADANA LOMBOK TIMUR
Authors: Amrullah Shafwan , Mikhratunnisa Mikhratunnisa , Pathiassana Mega Trishuta 
Published: September 2023

Pengembangan Usaha Mikro Kecil dan Menengah selalu memberikan perhatian khusus dari semua kalangan. Hal ini disebabkan karena kurangnya pengetauan dan teknologi yang dimilikinya, terutama UMKM yang bergelut di bidang makanan. Salah satu usaha yang dilakukan oleh UMKM Desa Sukadana adalah proses pembuatan saus tomat dan sambal. Akan tetapi produksi saus yang dilakukan mengalami kegagalan di bagian proses pembuatan. Sehingga pada kegiatan ini, Program Studi teknologi Industri Pertanian, Universitas Teknologi Sumbawa melakukan kegiatan pengabdian masyarakat untuk memberikan pelatihan terhadap UMKM Desa Sukadana dalam hal proses pembuatan saus serta proses sterilisasi yang baik. Selain itu Prodi TIP juga memberikan pelatihan tentang pembuatan sterilizer berbasis sinar UV-C. Hasil kegiatan ini berupa dihasilkan pelatihan bermanfaat berupa pelatihan pembuatan saus tomat dan saus sambel yang baik dan berkualitas. Selain itu kegiatan ini juga berhasil memberikan pelatihan dan pengetahuan tentang proses sterilisasi yang baik sehingga produk yang dihasilkan tidak mengalami kegagalan seperti sebelumnya. Pada bagian akhir kegitan ini berupa pelatihan perancangan alat sterilisasi yang terbaru, yaitu menggunaka sinar UV-C sebagai alat sterilisasinya.

The development of Micro, Small and Medium Enterprises always gives special attention from all walks of life. This is due to a lack of knowledge and technology, especially MSMEs that are engaged in the food sector. One of the efforts made by SMEs in Sukadana Village is the process of making tomato sauce and chili sauce. However, the production of sauce that was carried out failed in the manufacturing process. So that in this activity, the Agricultural Industry Technology Study Program, Sumbawa University of Technology carried out community service activities to provide training for SMEs in Sukadana Village in terms of the process of making sauces and good sterilization processes. This activity was carried out for 1 day, namely on October 21, 2021. While the preparation process for the initial independent research was from July 6 to October 20, 2021. The training was attended by 9 people, with details of 3 people from the TIP Study Program and 6 people from MSMEs. The TIP Study Program also provides training on the manufacture of UV-C light-based sterilizers. This training in making tomato sauce and chili sauce can run well and with quality. In addition, this activity has also succeeded in providing training and knowledge about a good sterilization process so that the resulting product does not fail as before. At the end of this activity, there is training on the design of the latest sterilizer, namely using UV-C light asa sterilizer.
Spatio-Temporal Dynamics of Sediment Transport Pathways: Sand Apron Bars and Islands of Tokelau and Kiribati, Central Pacific
Authors: Rankey Eugene C. , Uriam Tion , Perez Mika 
Published: October 2023

Although there is general agreement that global change will influence low-lying atoll islands, considerable uncertainty remains concerning the nature, rates, and causes of morphological change (or, conversely, the stability) of islands. As the net geomorphical product of sediment erosion, transport, and accumulation, islands are intimately tied to reef flat sedimentological processes. Recognizing the morphodynamical linkages between reef flats and islands, the purpose of this study is to examine the nature and controls on spatial and temporal variations in sediment transport pathways on reef flats and their relation to island planform changes or stability on atolls of Tokelau and Kiribati. GIS analysis of historical aerial images and high-resolution remote-sensing data capture patterns of reef flat change up to 72 years in duration with up to weekly temporal resolution. Data reveal how granular materials that make up bars and islands on reef flats respond to physical oceanographic processes via sedimentary-geomorphical change across temporal scales, from “instantaneous” impacts of cyclones or swell events to seasonal to multi-decadal shifts. Each of these shifts is manifest as migration of sediment of island beaches and bar forms, but the character varies markedly—bars form new islands, others erode and disappear; some changes are cyclic, others are directional, still others are hybrid; sediment can be transported lagoonward, oceanward, along the reef flat, or in combinations thereof; and migration rates reach up to 10 s of m/month. Although sea-level change likely plays a modulating role, much of the considerable spatial and temporal variability relates to differences in energy controlled by seasonal change in swell direction and climate shifts. Nonetheless, sedimentary response to these external forcings at any specific location also is shaped by local factors, such as trade wind-generated lagoonal waves and currents, atoll lagoon size and depth, margin width and orientation relative to waves, and autogenic processes such as attachment of migrating bars. Collectively, these influences shape the spatially and temporally heterogeneous sediment flux to and from islands, and thus the variable response of islands to ongoing sea-level change. Understanding such local influences is requisite to predictive understanding of how global change might impact these sensitive seascapes.
Quantifying internal intervertebral disc strains to assess nucleus replacement device designs: a digital volume correlation and ultra-high-resolution MRI study
Authors: Rahman Tamanna , Tavana Saman , Baxan Nicoleta , Raftery Kay A. , Morgan George , Schaer Thomas P. , Smith Nigel , Moore Axel , Bull Jonathan , Stevens Molly M. , Newell Nicolas 
Published: October 2023

Introduction: Nucleus replacement has been proposed as a treatment to restore biomechanics and relieve pain in degenerate intervertebral discs (IVDs). Multiple nucleus replacement devices (NRDs) have been developed, however, none are currently used routinely in clinic. A better understanding of the interactions between NRDs and surrounding tissues may provide insight into the causes of implant failure and provide target properties for future NRD designs. The aim of this study was to non-invasively quantify 3D strains within the IVD through three stages of nucleus replacement surgery: intact, post-nuclectomy, and post-treatment.Methods: Digital volume correlation (DVC) combined with 9.4T MRI was used to measure strains in seven human cadaveric specimens (42 ± 18 years) when axially compressed to 1 kN. Nucleus material was removed from each specimen creating a cavity that was filled with a hydrogel-based NRD.Results: Nucleus removal led to loss of disc height (12.6 ± 4.4%, p = 0.004) which was restored post-treatment (within 5.3 ± 3.1% of the intact state, p &gt; 0.05). Nuclectomy led to increased circumferential strains in the lateral annulus region compared to the intact state (−4.0 ± 3.4% vs. 1.7 ± 6.0%, p = 0.013), and increased maximum shear strains in the posterior annulus region (14.6 ± 1.7% vs. 19.4 ± 2.6%, p = 0.021). In both cases, the NRD was able to restore these strain values to their intact levels (p ≥ 0.192).Discussion: The ability of the NRD to restore IVD biomechanics and some strain types to intact state levels supports nucleus replacement surgery as a viable treatment option. The DVC-MRI method used in the present study could serve as a useful tool to assess future NRD designs to help improve performance in future clinical trials.
Decreased cholinesterase level combined with renal dysfunction and sympathetic denervation associated with increased cardiac mortality in systolic heart failure
Authors: Doi Takahiro , Nakata Tomoaki , Tsuzuki Taro , Mita Tomohiro , Nagahara Daigo , Yuda Satoshi , Hashimoto Akiyoshi 
Published: September 2023

AimsCardiac mortality in patients with heart failure (HF) is likely to be aggravated by malnutrition, assessed by serum cholinesterase (ChE) level, as well as by kidney dysfunction or impairment of cardiac sympathetic denervation. Their prognostic interactions, however, have not been determined.MethodsA total of 991 systolic HF patients were enrolled in our HF database following clinical evaluation including evaluation of the nutrition state and assessment of standardized heart-to-mediastinum ratio (sHMR) of iodine-123-labeled meta-iodobenzylguanidine activity. Patients were followed up for an average of 43 months with the primary endpoint of fatal cardiac events (CEs).ResultsThe CE patient group had a lower level of ChE, lower estimated glomerular filtration rate (eGFR) and lower late sHMR than those in the non-CE patient group. A five-parameter model with the addition of serum ChE selected in the multivariate logistic analysis (model 2) significantly increased the AUC predicting risk of cardiac events compared with a four-parameter model without serum ChE (model 1), and net reclassification analysis also suggested that the model with the addition of serum cholinesterase significantly improved cardiac event prediction. Moreover, in overall multivariate Cox hazard analysis, serum ChE, eGFR and late sHMR were identified to be significant prognostic determinants. HF patients with two or all of the prognostic variables of serum ChE &lt; 230 U/L, eGFR &lt; 48.8 ml/min/1.73 m2 and late sHMR &lt; 1.90 had significantly and incrementally increased CE rates compared to those in HF patients with none or only one of the prognostic variables.ConclusionDecreases in cholinesterase level and kidney function further increase cardiac mortality risk in HF patients with impairment of cardiac sympathetic innervation.
Atrioventricular nodal reentry tachycardia treatment using CARTO 3 V7 activation mapping: a new era of slow pathway radiofrequency ablation is under coming
Authors: Chieffo Enrico , D’Amore Sabato , De Regibus Valentina , Dossena Cinzia , Frigerio Laura , Taravelli Erika , Ferrazzano Carolina , De Iuliis Pasquale , Cacucci Michele , Landolina Maurizio E. 
Published: September 2023

BackgroundSlow pathway (SP) ablation is the cornerstone for atrioventricular nodal reentry tachycardia (AVNRT) treatment, and a low-voltage bridge offers a good target during mapping using low x-ray exposure. We aimed to assess a new tool to identify SP by activation mapping using the last CARTO3® version, i.e., CARTO PRIME® V7 (Biosense Webster, Diamond Bar, CA, USA)Methods and resultsRight atrial septum and triangle of Koch 3D-activation map were obtained from intracardiac contact mapping during low x-ray CARTO 3® procedure. In 60 patients (mean age 60.3 ± 14.7, 61% females) undergoing ablation for AVNRT, an automatic activation map using a DECANAV® mapping catheter and CARTO® Confidense™, Coherent, and FAM DX software modules were obtained. The SP was identified in all patients as the latest atrioventricular node activation area; RF catheter ablation (RFCA) in that region elicited junctional beats. The mean procedural time was 150.3 ± 48.3 min, the mean fluoroscopy time exposure was 2.9 ± 2 min, the mean dose-area product (DAP) was 16.5 ± 2.7 cGy/cm2. The mean number of RF applications was 3.9 ± 2, the mean ablation index was 428.6 ± 96.6, and the mean contact force was 8 ± 2.8 g. There were no adverse event during the procedure, and no AVNRT recurrences occurred during a mean follow-up of 14.3 ± 8.3 months.ConclusionAblation of the SP by automatic mapping using Confidense™, Coherent, and FAM DX software modules is an innovative, safe, and effective approach to AVNRT ablation. The CARTO3® V7 system shows on a 3D map the latest AV node activation area during sinus rhythm allowing low fluoroscopy time and highly effective RFCA.
Diagnostic accuracy of noninvasive fractional flow reserve derived from computed tomography angiography in ischemia-specific coronary artery stenosis and indeterminate lesions: results from a multicenter study in China
Authors: Ding Yaodong , Li Quan , Zhang Yang , Tang Yida , Zhang Haitao , Yang Qing , Shou Xiling , Ye Yicong , Zhao Xiliang , Ye Yi , Zhang Chao , Liu Yuqi , Zeng Yong 
Published: October 2023

BackgroundTo determine the diagnostic performance of a novel computational fluid dynamics (CFD)-based algorithm for in situ CT-FFR in patients with ischemia-induced coronary artery stenosis. Additionally, we investigated whether the diagnostic accuracy of CT-FFR differs significantly across the spectrum of disease and analyzed the influencing factors that contribute to misdiagnosis.MethodsCoronary computed tomography angiography (CCTA), invasive coronary angiography (ICA), and FFR were performed on 324 vessels from 301 patients from six clinical medical centers. Local investigators used CCTA and ICA to conduct assessments of stenosis, and CT-FFR calculations were performed in the core laboratory. For CCTA and ICA, CT-FFR ≤ 0.8 and a stenosis diameter ≥ 50% were identified as lesion-specific ischemia. Univariate logistic regression models were used to assess the effect of features on discordant lesions (false negative and false positive) in different CT-FFR categories. The diagnostic performance of CT-FFR was analyzed using an invasive FFR ≤ 0.8 as the gold standard.ResultsThe Youden index indicated an optimal threshold of 0.80 for CT-FFR to identify functionally ischemic lesions. On a per-patient basis, the diagnostic sensitivity, specificity, accuracy, positive predictive value (PPV), and negative predictive value (NPV) for CT-FFR were 96% (91%–98%), 92% (87%–96%), 94% (90%–96%), 91% (85%–95%), and 96% (92%–99%), respectively. The diagnostic efficacy of CT-FFR was higher than that of CCTA without the influence of calcification. Closer to the cut point, there was less certainty, with the agreement between the invasive FFR and the CT-FFR being at its lowest in the CT-FFR range of 0.7–0.8. In all lesions, luminal stenosis ≥ 50% significantly affected the risk of reduced false negatives (FN) and false positives (FP) results by CT-FFR, irrespective of the association with calcified plaque.ConclusionsIn summary, CT-FFR based on the new parameter-optimized CFD model has a better diagnostic performance than CTA for lesion-specific ischemia. The presence of calcified plaque has no significant effect on the diagnostic performance of CT-FFR and is independent of the degree of calcification. Given the range of applicability of our software, its use at a CT-FFR of 0.7–0.8 requires caution and must be considered in the context of multiple factors.
An application and exploration of entrustable professional activities in Chinese orthopaedic postgraduate residents training: a pilot study
Authors: Qu Rundong , Yang Xu , Li Ying , Gao Fuqiang , Sun Wei , Li Zirong 
Published: October 2023

BackgroundThrough the standardization of residency training in certain Chinese medical education institutions, it was discovered that the current evaluation system falls short in accurately assessing residents’ professional skills in clinical practice. Therefore, we developed the list of Entrustable Professional Activities (EPAs) in orthopaedic residency training to explore a new evaluation system.MethodsThe process of constructing EPAs includes seven steps. 40 orthopaedic residents were randomly assigned to two groups (20 in each). The experimental group used the EPAs evaluation system while the control group employed the traditional Mini Clinical Exercise (Mini-CEX) system. Post-residency, theoretical and practical tests were conducted to measure training effectiveness. Additionally, a survey gauged teaching satisfaction, knowledge mastery, and course engagement in both groups.ResultsThe control group scored an average of 76.05 ± 10.58, while the experimental group achieved 83.30 ± 8.69 (p &lt; 0.05) on the combined theoretical and practical test. Statistically significant differences were observed between the two groups concerning teaching satisfaction, knowledge mastery, and course engagement.ConclusionThe application of EPAs in orthopaedic residency training yielded higher theoretical and practical test scores compared to the traditional formative evaluation system. It also enhanced teaching satisfaction, knowledge mastery, and course engagement. The EPAs present a potential model for national orthopaedic residency training.
Cardiovascular and metabolic status in patients with primary hyperparathyroidism: a single-center experience
Authors: Dobreva Ekaterina A. , Gorbacheva Anna M. , Bibik Ekaterina E. , Eremkina Anna K. , Elfimova Alina R. , Salimkhanov Rustam Kh. , Kovaleva Elena V. , Maganeva Irina S. , Mokrysheva Natalia G. 
Published: September 2023

IntroductionCardiovascular diseases (CVD) and metabolic disorders (MD) have retained leading positions in the structure of morbidity and mortality for many years. Primary hyperparathyroidism (PHPT) is also associated with a greater incidence of CVD and MD. The aim of the present study was to describe the prevalence and structure of CVD and MD in hospitalized patients with PHPT and to search for possible associations between these pathologies.Methods838 patients with a verified PHPT were included in the study. The studied cohort was divided into 2 groups according to their age at the time of admission: patients aged 18 to 49 years (group A, n = 150); patients aged 50 years and older (group B, n = 688).ResultsThere were no significant differences between two groups in parameters of calcium-phosphorus metabolism. Obesity was diagnosed in 24.2% of patients in group A and in 35.9% in group B. Type 2 diabetes mellitus was more common in older patients (14.4% in group B vs. 2.6% in group A). Arterial hypertension, ischemic heart disease, chronic heart failure and brachiocephalic arteries atherosclerosis were more frequent in older patients, occurring in 79.1%, 10.8%, 8.4%, and 84% of cases respectively. The cutoff points that increased the risk of CVD detection turned out to be age above 56 years, eGFR below 92 ml/min/1.73m2, BMI above 28.3 kg/m2.DiscussionThe present study demonstrated a high incidence of some CVD, as well as disorders of lipid, carbohydrate and purine metabolism in patients with PHPT.
Application of calcium-to-phosphorus (Ca/P) ratio in the diagnosis of pseudohypoparathyroidism: another piece in the puzzle of diagnosis of Ca-P metabolism disorders
Authors: De Vincentis Sara , Del Sindaco Giulia , Pagnano Angela , Brigante Giulia , Moretti Antonio , Zirilli Lucia , Rochira Vincenzo , Simoni Manuela , Mantovani Giovanna , Madeo Bruno 
Published: October 2023

ObjectiveThe serum calcium (Ca)–to–phosphorus (P) ratio has been proposed to identify patients with primary hyperparathyroidism and chronic hypoparathyroidism (HPT), but it has never been tested in pseudohypoparathyroidism (PHP). The aim of this study was to test the performance of Ca/P ratio in PHP diagnosis compared with that in healthy subjects and patients with HPT for differential diagnosis.DesignA retrospective, cross-sectional, and observational study was carried out.MethodsSerum Ca, P, creatinine, parathyroid hormone (PTH), and albumin were collected. Ca and P were expressed in mmol/L. Ca/P diagnostic performance was evaluated by receiver operating characteristic curve, sensitivity, specificity, and accuracy.ResultsA total of 60 patients with PHP, 60 patients with HPT, and 120 controls were enrolled. The Ca/P ratio was lower in patients with PHP and HPT than that in controls (p &lt; 0.0001). The cutoff of 1.78 (2.32 if Ca and P measured in mg/dL) for Ca/P ratio could identify patients with PHP and HPT among the entire cohort (sensitivity and specificity of 76%). No valid cutoff of Ca/P was found to distinguish patients with PHP from patients with HPT; in this case, PTH above 53.0 ng/dL identified patients with PHP (sensitivity and specificity of 100%). The index (Ca/P × PTH) above 116 ng/L recognized patients with PHP from controls (sensitivity of 84.7% and specificity of 87.4%), whereas (Ca/P × PTH) below 34 ng/L recognized patients with HPT from controls (sensitivity of 88.9% and specificity of 90.8%).ConclusionsThe Ca/P ratio below 1.78 (2.32 CU) is highly accurate to identify patients with PHP and HPT, although it is not reliable to differentiate these two conditions. The index (Ca/P × PTH) is excellent to specifically recognize PHP or HPT from healthy subjects.