bluuebunny/crossref_metadata_2025_split huggingface dataset:
Neuropathic-Like Symptoms as Preoperative Predictor for Chronic Postsurgical Pain and Dissatisfaction in Total Hip and Knee Arthroplasty Patients
Authors: Blikman Tim , Akker-Scheek Inge , Raaij Tom. M. , Dijkstra Baukje , Bulstra Sjoerd K. , Stevens Martin 
Published: January 2024

Abstract

Background
A significant portion of total knee and hip arthroplasty (TKA/THA) patients experience chronic postsurgical pain (CPSP). The proportion of suffering patients runs in the 10–34% range. CPSP is the main cause of postoperative dissatisfaction. For prevention purposes it is essential to know which preoperative factors are predictive for CPSP. It is unknown whether neuropathic-like symptoms add predictive value to known predictors for CPSP and dissatisfaction after TKA/THA.
Methods
A prospective cohort study including 453 TKA/THA patients (TKA 208, THA 245). Preoperatively, pain intensity (numeric rating scale [NRS]) and neuropathic-like symptoms (modified-painDETECT questionnaire [mPDQ]; score ≥ 13) were obtained. One year postoperatively CPSP and dissatisfaction (single NRS item (0–10); dissatisfied: ≤ 5) was captured. CPSP by means of the Oxford Knee/Hip Score (moderate or severe pain on question 1), as well by pain intensity at rest and with movement (NRS ≥ 1). Multivariate logistic regression modeling was used to determine the additive predictive value of preoperative neuropathic-like symptoms (mPDQ ≥ 13) on experiencing CPSP and dissatisfaction for the total group and knee and hip patients separately.
Results
The odds (p < 0.05) of experiencing CPSP at one year ranged from 2.16 (total group) to 4.15 (hip patients) for patients that experienced neuropathic-like symptoms preoperatively (m-PDQ ≥ 13). Neuropathic-like symptoms had no additional value for predicting CPSP in knee patients nor for predicting dissatisfaction.
Conclusion
The results of this study showed that neuropathic-like symptoms (m-PDQ ≥ 13) have an additional predictive value over known predictors, especially in hip patients. Patients with neuropathic-like symptoms have over twice the odds of suffering from CPSP one year after TKA/THA.
Epidemiological characteristics of eleven common respiratory viral infections in children
Authors: Li Suling , Xue Zhengfeng , Feng Yuxin , Zhou Xue , Qi Yang , Feng Na , Li Yuanxia 
Published: January 2024

Abstract

Background Lower respiratory tract infections (LRTIs) are one of the leading causes of hospital admissions among children. In this study, we aimed to describe the epidemiological characteristics of viral pathogens associated with LRTIs in hospitalized children in Yan'an; this has yet to be reported in the literature and may guide public health interventions and resource allocation in this region.
Methods Between June 2021 and May 2023, we conducted a retrospective analysis of the results of viral detection using oral pharyngeal swabs from 4565 children with LRTIs in the Inpatient Department of Yan'an University Affiliated Hospital. Eleven respiratory viruses, including influenza A virus (Flu A), influenza A H1N1 virus (H1N1), seasonal influenza A H3N2 virus (H3N2), influenza B virus (Flu B), parainfluenza virus (HPIV), adenovirus (HADV), bocavirus (HBoV), rhinovirus (HRV), metapneumovirus (HNPV), coronavirus (HCoV), and respiratory syncytial virus (HRSV), were confirmed by applying a multiplex real-time polymerase chain reaction (PCR) kit for respiratory viruses. We evaluated the epidemiological features of infections caused by respiratory pathogens, including aging and the seasonal variations of different pathogens, and explored the high-risk factors associated with virus-caused pneumonia.
Results At least one virus was detected in all 4565 cases; the positivity rate was 27.95%. We also detected a total of 1,276 cases with mixed infections (with two or more viruses). Of the positive cases, 59.3% were male and 40.7% were female (x2 = 0.41, P = 0.68). The highest positivity rates for respiratory pathogens were observed for HRSV, HRV, and HADV, at 5.98%, 5.67%, and 4.38%, respectively. We also observed variations in the number and positivity rates of respiratory pathogen infections by season and age. HPIV (x2 = 12.05，P < 0.05) and HADV (x2 = 11.73，P < 0.05) were more common in children under 3 years-of-age.
Conclusions In conclusion, our analysis revealed that respiratory pathogen infections varied by gender, season, and age in the enrolled population of children.
Developing a distributed modeling framework considering the spatiotemporally varying hydrological processes for sub-daily flood forecasting in semi-humid and semi-arid watersheds
Authors: Li Xiaoyang , Ye Lei , Gu Xuezhi , Chu Jinggang , Wang Jin , Zhang Chi , Zhou Huicheng 
Published: January 2024

Abstract
The complex and varied climate, short duration and high intensity of rainfall, and complicated subsurface properties of semi-humid and semi-arid watersheds pose challenges for sub-daily flood forecasting. Previous studies revealed that lumped models are insufficient because they do not effectively account for the spatial variability of hydrological processes. Extending the lumped model to a distributed modeling framework is a reliable approach for runoff simulation. However, existing distributed models do not adequately characterize the strong spatiotemporal variability of the sub-daily hydrological processes in semi-humid and semi-arid watersheds. To address the above concerns, a distributed modeling framework was proposed that is extended by lumped models and accounts for the effects of time-varying rainfall intensity and reservoir regulation on hydrological processes. Moreover, the Fourier Amplitude Sensitivity Test (FAST) method is performed to identify the sensitive parameters for efficient calibration. To evaluate the performance of the proposed distributed model, it was tested in eight watersheds. The results indicate that the proposed distributed model simulates sub-daily flood events with mean evaluation metrics of 0.80, 9.2%, 13.0%, and 1.05 for NSE, BIAS, RPE, and PTE, respectively, superior to the lumped model. Furthermore, to further evaluate the difference between the proposed distributed model and the existing distributed models, it was compared with the Variable Infiltration Capacity (VIC) model at various time steps, including 3h, 6h, 12h, and24 h. The proposed distributed model was able to better capture the flooding processes at shorter time steps, especially 3 h. Therefore, it can be considered a practical tool for sub-daily flood forecasting in semi-humid and semi-arid watersheds.
Passive imaging through inhomogeneous scattering media
Authors: Bian Yaoming , Wang Fei , Liu Haishan , Yuan Haiming , Li Siteng , Huang Wenxin , Situ Guohai 
Published: January 2024

Abstract
According to the atmospheric scattering model (ASM), the object signal's attenuation diminishes exponentially as the imaging distance increases. This imposes limitations on ASM-based methods in situations where the scattering medium one wish to look through is inhomogeneous. Here, we extend ASM by taking into account the spatial variation of the medium density, and propose a two-step method for imaging through inhomogeneous scattering media. In the first step, the proposed method eliminates the direct current component of the scattered pattern by subscribing to the estimated global distribution (background). In the second step, it eliminates the randomized components of the scattered light by using threshold truncation, followed by the histogram equalization to further enhance the contrast. Outdoor experiments were carried out to demonstrate the proposed method.
Continuously Fiber Path Optimization Based on Gaussian Distribution Function with Convergent Material Orientation
Authors: Zhang Leen , Lu Qian , Hua Yilian , Wang Xiaoping 
Published: January 2024

Abstract
How to optimize the fiber placementpath is of great significance for improving the mechanical properties of composite material. Fiber orientation discretization is regarded as a common means to solve the above problem, and themethod with multivariate is generally adopted to find the optimal fiber angle. However, the cost is high, and eventually there are still multiple discrete angles as the result, which cannot meet the ultimate requirements of fiber orientation convergence and path continuity. Therefore, an optimization method of fiber placement path based on Gaussian distribution function is proposed, where only one variable is used to select the optimized angle among any number of discrete placement angles. By adjusting several parameters in the Gaussian distribution function, the fiber orientation is converged, and the path continuity is realized by the spatial filtering. New method can be used to avoid the multiple local minima problem found in fiber orientation discretization process. Numerical experiments are carried out to optimize the fiber placement path of aerofoil skin and rocket interstagesection skin respectively, which shows the efficiency of the proposed method.
One-stop hybrid operation versus microsurgery for treating brain arteriovenous malformation in children--A retrospective case series
Authors: Fan Chen , Haibing Liu , Jianbin Ying , Qingshuang Zhao , Kaiming Chen , Jingfang Hong , Qinchuan Liang , Junjie Jing 
Published: January 2024

Abstract
Background
Brain arteriovenous malformation (AVM) is one of the most common causes of cerebral hemorrhage in children. The effectiveness of one-stop hybrid operation in the treatment of AVMs in adults has been widely confirmed, but there are few studies in children. This study intends to analyze the role and significance of one-stop hybrid operation versus microsurgery in the treatment of AVMs in children by retrospective analysis.
Methods
A total of 57 children (≤ 18 years old) with AVMs who were admitted to the 900th Hospital of United Logistics Support Forces and Fujian Children's Hospital between September 2018 and August 2022 were retrospectively analyzed. According to the inclusive criteria and exclusion criteria, 38 cases were included, and they were divided into microsurgery group (25 cases) and hybrid operation group (13 cases) according to the different treatment modalities. Observation indicators included clinical characteristics: gender, age, initial symptom, presence or absence of signs, GCS score, Hunt-Hess grade; imaging characteristics such as the location of AVMs, Spetzler-Martin (S-M) grade, whether accompanied by intraventricular hemorrhage, treatment and prognosis indicators such as intraoperative blood loss, operation time, imaging cure, postoperative complications, hospital stay, and 3 months and 6 months mRS after operation.
Results
The proportion of female patients (P = 0.042), the proportion of patients whose AVMs was located on the supratentorial (P = 0.034) and the proportion of patients whose S-M grade was above grade III (P = 0.003) in the hybrid operation group were higher than those of the microsurgery group. The intraoperative blood loss (P < 0.001), operation time (P < 0.001) and postoperative hospital stay (P = 0.024) of patients in the microsurgery group were higher than those in the hybrid operation group. The presence of signs and S-M grade may be relevant factors in predicting the surgical approach, and the probability of selecting hybrid operation for each step of increasing S-M grade is 3.046 times that of microsurgery.
Conclusions
One-stop hybrid operation is effective and safe for the treatment of brain AVMs in children. High S-M grade of AVMs is more suitable for hybrid operation.
Approaches to Embryonic Neurodevelopment: From Neural Cell to Neural Tube Formation through Mathematical Models
Authors: Rafati Ali H. , Joca Sâmia , Vontell Regina T. , Wegener Gregers , Ardalan Maryam 
Published: January 2024

Abstract

The human central nervous system (CNS) undergoes development from early embryonic stages to well beyond birth, with various neurological and neuropsychiatric diseases originating from prenatal events. Mathematical models offer a direct avenue for understanding these neurodevelopmental processes, particularly during the embryonic period. However, approaching and initiating such modeling presents challenges, including the formulation of appropriate equations that capture the dynamics of neurodevelopment.Therefore, this study aimed to comprehensively address the mathematical challenges by exploring different approaches. The approaches were divided into three embryonical categories: cell division, neural tube growth and neural plate growth. We concluded that the neural plate growth approach provides a suitable platform for simulation of brain formation/neurodevelopment compared to cell division and neural tube growth. We devised a novel equation and designed algorithms that include geometrical and topological algorithms that could fit most of the essential elements of the neurodevelopmental process during the embryonic period.
Rapid developmental changes in retinal organoids after brief exposure to extrinsic electrical fields
Authors: Thomas Biju , Nair Deepthi S. Rajendran , Gupta Anika , Iseri Ege , Shehi Andrea , Wei Tianyuan , Quach Le Tam Phuong , Seiler Magdalene , Lazzi Gianluca 
Published: January 2024

Abstract

Considering the significant role played by both intrinsic and extrinsic electric fields in the growth and maturation of the central nervous system, the impact of short exposure to external electric fields on the development and differentiation of retinal organoids was investigated. Organoids derived from human embryonic stem cells at day 80, a critical time point in their differentiation and maturation, were used. A single 60-minute exposure to distinct biphasic electrical fields expedited the commitment and maturation of the photoreceptor lineage. Morphology, qPCR, and RNA sequencing data revealed elevated expression of rod photoreceptors, muller cells, horizontal cells, and amacrine cells, alongside the downregulation of retinal pigment epithelium and retinal ganglion cell genes. Furthermore, our study demonstrated varying degrees of organoid development and maturation depending on the specific electrical field applied. These findings provide valuable insights into the profound influence of extrinsic electrical fields on early retinal development and emphasize that several existing limitations in retinal organoid technology can be easily overcome by using suitable electrical field parameters without applying chemicals and small molecules.
Isolated persistent left superior vena cava in adults: A case report and brief literature review
Authors: Zhang Dian , Pan Mei-Fang 
Published: January 2024

Abstract
Background
Isolated persistent left superior vena cava is an extremely rare congenital anomaly. Due to abnormal venous drainage, isolated persistent left superior vena cava is often associated with abnormalities in the cardiac conduction system, leading to rapid or slow arrhythmias.
Case presentation:
We report a 37-year-old asymptomatic male patient who accidentally discovered isolated persistent left superior vena cava through chest echocardiography during routine physical examination. The patient has no history of cyanosis, breathing difficulties, chest pain, or family history of heart disease.
Conclusions
Although isolated persistent left superior vena cava patients are often asymptomatic in the early stages, it may increase the risk of central venous access, cardiothoracic surgery, and pacemaker implantation. Noninvasive echocardiography can provide a basis for early diagnosis of asymptomatic patients and has certain clinical significance.
Adsorption ability of DNA/calcium alginate magnetic aerogel microspheres toward benzo(a)anthracene
Authors: Huang Guoxia , Ma Ji , Li Junsheng 
Published: January 2024

Abstract
With the increasing development of industry, polycyclic aromatic hydrocarbons (PAHs) pollution is becoming increasingly serious, posing great harm to the health of humans and other organisms. It is urgent to develop effective solutions.In this study, DNA/calcium alginate magnetic aerogel microspheres were prepared based on the gel properties of sodium alginate and the magnetism of ferric oxide, which were used to remove benzo(a)anthracene (BaA) from aqueous solution. The aerogel microspheres were irregular spherical, with concave convex surface and good water absorption. The pores were mostly mesoporous. The aerogel microspheres had good adsorption on BaA and were easy to be magnetically separated. When the initial concentration of BaA was 350 µg/L, the removal efficiency was 98.52% when incubated at 25 ℃ and pH 7.0 for 50 min. The adsorption process accorded with Langmuir model and pseudo-2nd -order kinetic model. For natural river samples containing BaA, the removal efficiency was above 98.45% when the BaA initial concentration was in the range of 50–300 µg/L.The aerogel microspheres have high adsorption capacity, and the adsorption of BaA was simple and time-consuming, which have great potential application value in water purification.
Pulmonary function trajectories in COVID-19 survivors with- and without pre-existing respiratory disease at three and twelve months after hospital discharge
Authors: Gach Debbie , Beijers Rosanne J.H.C.G. , Zeeland Roel van , Boogaart Vivian van Kampen-van den , Posthuma Rein , Schols Annemie M.W.J. , Bergh Joop P. van den , Osch Frits H.M. van 
Published: January 2024

Abstract

A significant proportion of COVID-19 survivors still experience a reduced diffusion capacity three and twelve months after discharge. We aimed to compare pulmonary function trajectories between hospitalized COVID-19 patients with pre-existing respiratory disease (PRD) and patients without pre-existing respiratory disease (Non-PRD) at three and twelve months after hospital discharge. This single-centre retrospective cohort study included COVID-19 patients admitted to the VieCuriMedical Centre (Venlo, the Netherlands) between February and December 2020 that were invited to the outpatient clinic at three and twelve months after discharge. During this visit, pulmonary function tests were performed and impairments were based on lower limit of normal. Data of 239 patients were analysed (65% male, 66±10 years, and 26% with a history of respiratory disease). Three months after discharge, 49% and 64% of the Non-PRD patients (n=177) and PRD patients (n=62) had a low diffusion capacity, respectively. This improved over time in Non-PRD patients (p=0.003), but not in PRD patients (p=0.250). A low diffusion capacity was still observed in 34% and 57% of the Non-PRD and PRD group, respectively, twelve months after discharge. Pulmonary function impairments, mainly a reduced diffusion capacity, are observed among hospitalized COVID-19 patients with PRD and Non-PRD, at three and twelve months follow-up. Although diffusion capacity impairments restore over time in Non-PRD patients, poor recovery was observed among PRD patients.
Prediction of Left Ventricular Echocardiography Mass from Romhilt-Estes score in hypertensive patients in Kinshasa: Cross-sectional study
Authors: Otshudi Noel Onembo , Mbunga Branly Kilola , Nkodila Aliocha Natuhoyila , Lubenga Yves , Ngoy Georges Nduba , Samafundu Yannick Mundedi , Buila Nathan Bimbi , M’buyamba-Kabangu Jean René 
Published: January 2024

Abstract

Introduction :
Transthoracic Doppler echocardiography (TDE) is an essential tool in the diagnosis of left ventricular hypertrophy (LVH), alongside the Gold standard which is magnetic resonance imaging (MRI), which is much more expensive. TDE is an easily accessible tool in developed countries but remains difficult to access in most rural areas of sub-Saharan African countries, making the diagnosis of LVH difficult. However, it is a predictive factor of cardiovascular events in hypertensive patients. The electrocardiogram being more accessible in these environments, we evaluated its performance in the diagnosis of LVH and especially sought to predict left ventricular mass from the most sensitive and specific electrocardiographic score in our study, the Romhilt-Estes.
Method
This is an analytical study of a consecutive series of cases, which covered the period from July to September 2018, in five hospital facilities in Kinshasa. Socio-demographic parameters, ECG, and TDE were studied. Spearman's Rho correlation coefficient and Bland Altman concordance test were used for numerical values. And multiple linear regression modeling was used for the entire workforce and in each sex separately.
Results
The area below the ROC curve of the Romhilt-Estes score was significantly greater than that of the other ECG indices (X²=4.78; p = 0.0289); the most important correlation coefficient was observed between the MVG and the Romhilt-Estes score (0.436) with better alignment and dispersion (95% CI) and finally in the multiple linear regression, age and the score of Romhilt-Estes emerged in both sexes as independent determinants of LVM.
Conclusion
Age and sex are variables that influence the modeling of LVM based on the Romhilt-Estes score. But the mathematical models found have a weak prediction.
External carotid artery-to-petrous internal carotid artery radial artery graft bypass for a giant high cervical aneurysm
Authors: Gao Kaiming , Guo Wenqiang , Tong Xiaoguang 
Published: January 2024

Abstract
Objective To investigate optimal treatment strategies for giant high-cervical internal carotid artery aneurysms.
Methods A retrospective analysis was conducted, examining clinical data, surgical approaches, and postoperative outcomes in a case involving a patient with a giant high-cervical internal carotid artery aneurysm. Additionally, pertinent literature was reviewed to contextualize the findings.
Results A 52-year-old male patient presented with a one-year history of intermittent coughing, exacerbated by a two-month history of headaches. Digital Subtraction Angiography (DSA) revealed the presence of a giant high-cervical internal carotid artery aneurysm on the right side. The patient underwent an external carotid artery-radial artery-internal carotid artery petrosal segment bypass and aneurysm isolation surgery. Postoperative angiography demonstrated the disappearance of the aneurysm and patency of the bypass. Notably, there were no occurrences of new cerebral ischemia or infarction, no manifestation of new neurological dysfunction, and a marked improvement in the patient's original symptoms.
Conclusion The treatment of giant high-cervical internal carotid artery aneurysms necessitates cerebral vascular bypass surgery, with the external carotid artery-radial artery-internal carotid artery petrosal bone segment bypass proving to be an efficacious and preferable therapeutic modality for such lesions.