bluuebunny/crossref_metadata_2025_split huggingface dataset:
Higher-dimensional holographic superconductors in Born–Infeld electrodynamics and f(R) gravity
Authors: Roussev Alexandar 
Published: February 2024

AbstractIn this paper, the properties of higher dimensional holographic superconductors are studied in the background of f(R) gravity and Born–Infeld electrodynamics. A specific model of f(R) gravity is considered, allowing a perturbative approach to the problem. The Sturm–Liouville eigenvalue problem is used to analytically calculate the critical temperature and the condensation operator. An expression for the critical temperature in terms of the charge density including the correction from modified gravity is derived. It is seen that the higher values of the Born–Infeld coupling parameter make the condensation harder to form. In addition, the limiting values of this parameter, above which Born–Infeld electrodynamics cannot be applied, are found for different dimensions. Another interesting property is that the increasing modifications of f(R) gravity lead to larger values of the critical temperature and a decrease in the condensation gap, which means that the condensation is easier to form.
High-resolution stratigraphy and characterization of reservoir-critical heterogeneities in the giant Tupi Field, pre-salt Santos Basin, Brazil
Authors: Pedrinha Saulo , de Mello Artagão Victor 
Published: February 2024

Abstract
The large oil discoveries that have occurred in recent decades in the pre-salt section of the South Atlantic sedimentary basins have promoted a significant volume of scientific research regarding the origin of these deposits. Most of the current studies of this stratigraphic interval focus on regional aspects or sedimentological and diagenetic processes. However, few studies encompass the geological characteristics of the pre-salt deposits from a reservoir-scale perspective.
This work addresses the construction of a detailed reservoir-oriented stratigraphic framework for the giant Tupi Field. Discovered in 2006 following a successful exploratory campaign in the southeastern Brazilian deep-water, the Tupi Field's main reservoirs are sag-phase carbonates from the Aptian-aged Barra Velha Formation. These rocks accumulated in alkaline to highly alkaline lacustrine settings, which allowed the development of unusual syngenetic elements, such as magnesian clays, calcitic spherulites and calcitic shrubs. The reservoirs' depositional organization was essentially conditioned by climatic oscillations and tectonic activity, which controlled sedimentation rates and accommodation styles through space and time.
The high-resolution stratigraphic framework established in this article supports a detailed understanding, at different scales, of the Tupi Field's sedimentological evolution and its main vertical and lateral facies distribution. These aspects have, in turn, provided essential inputs for reservoir characterization and constrained critical heterogeneities of the 3D geocellular model, even in reservoirs affected by diagenetic processes.
Sleep and Risk of Pancreatic Cancer in the UK Biobank
Authors: Freeman Joshua R. , Saint-Maurice Pedro F. , Zhang Ting , Matthews Charles E. , Stolzenberg-Solomon Rachael Z. 
Published: February 2024

Abstract

Background:
Light at night, which may cause circadian disruption, is a potential pancreatic cancer risk factor. However, evidence from related exposures such as poor sleep health and shift work remains inconclusive and sparsely investigated.

Methods:
We evaluated associations between self-reported typical sleep duration, chronotype, shift work, insomnia symptoms, snoring, and daytime sleeping and pancreatic ductal adenocarcinomas (PDAC) incidence among 475,286 UK Biobank participants. We used Cox proportional hazards models to estimate HRs and 95% confidence intervals (CI) adjusting for age, sex, body mass index, smoking status, duration, and frequency, alcohol intake, diabetes status, race, and employment/shift work.

Results:
Over 14 years of follow-up, 1,079 adults were diagnosed with PDAC. There were no associations observed between sleep characteristics, including sleep duration [&lt;7 vs. 7–&lt;9 hours; HR, 1.03; 95% CI, 0.90–1.19; ≥9 hours; HR, 1.00 (0.81–1.24), evening chronotype (“definitely” an evening person vs. “definitely” a morning person; HR, 0.99 (0.77–1.29)], shift work, insomnia symptoms, snoring, or daytime sleep and PDAC risk.

Conclusions:
Self-reported typical sleep characteristics and shift work were not associated with PDAC risk.

Impact:
Considering the role of light at night and shift work in circadian disruption and cancer risk, it is plausible that poor sleep health among a general population may be related to cancer risk through similar sleep and circadian disrupting processes. This work may suggest that typical sleep characteristics and shift work are not associated with PDAC, although additional work is needed to confirm these findings.
Differences in Cardiometabolic Proteins in Pregnancy Prioritize Relevant Targets of Preeclampsia
Authors: Lindley Kathryn J. , Perry Andrew , Jacobs Marni , Petty Lauren , Amancherla Kaushik , Zhao Shilin , Barker Claire , Davila-Roman Victor G. , Khan Sadiya S. , Osmundson Sarah S. , Tanriverdi Kahraman , Freedman Jane E. , Below Jennifer , Shah Ravi V. , Laurent Louise C. 
Published: February 2024

BACKGROUND:
Preeclampsia is a hypertensive disorder of pregnancy characterized by widespread vascular inflammation. It occurs frequently in pregnancy, often without known risk factors, and has high rates of maternal and fetal morbidity and mortality. Identification of biomarkers that predict preeclampsia and its cardiovascular sequelae before clinical onset, or even before pregnancy, is a critical unmet need for the prevention of adverse pregnancy outcomes.

METHODS:
We explored differences in cardiovascular proteomics (Olink Explore 384) in 256 diverse pregnant persons across 2 centers (26% Hispanic, 21% Black).

RESULTS:
We identified significant differences in plasma abundance of markers associated with angiogenesis, blood pressure, cell adhesion, inflammation, and metabolism between individuals delivering with preeclampsia and controls, some of which have not been widely described previously and are not represented in the preeclampsia placental transcriptome. While we observed a broadly similar pattern in early (<34 weeks) versus late (≥34 weeks) preeclampsia, several proteins related to hemodynamic stress, hemostasis, and immune response appeared to be more highly dysregulated in early preeclampsia relative to late preeclampsia.

CONCLUSIONS:
These results demonstrate the value of performing targeted proteomics using a panel of cardiovascular biomarkers to identify biomarkers relevant to preeclampsia pathophysiology and highlight the need for larger multiomic studies to define modifiable pathways of surveillance and intervention upstream to preeclampsia diagnosis.
Sympathetic Neural Control at Rest and During the Cold Pressor Test in Patients With Heart Failure With Preserved Ejection Fraction
Authors: Takeda Ryosuke , Hissen Sarah L. , Akins John D. , Washio Takuro , Hearon Christopher M. , MacNamara James P. , Sarma Satyam , Levine Benjamin D. , Fadel Paul J. , Fu Qi 
Published: February 2024

Background:
We tested the hypothesis that patients with heart failure with preserved ejection fraction (HFpEF) would have greater muscle sympathetic nerve activity (MSNA) at rest and sympathetic reactivity during a cold pressor test compared with non–heart failure controls. Further, given the importance of the baroreflex modulation of MSNA in the control of blood pressure (BP), we hypothesized that patients with HFpEF would exhibit a reduced sympathetic baroreflex sensitivity.

METHODS:
Twenty-eight patients with HFpEF and 44 matched controls (mean±SD: 71±8 versus 70±7 years; 9 men/19 women versus 16 men/28 women) were studied. BP, heart rate, and MSNA (microneurography) were measured during 6 to 10 minutes of supine rest and the 2-minute cold pressor test. Spontaneous sympathetic baroreflex sensitivity was assessed during supine rest.

Results:

Patients with HFpEF had higher resting MSNA burst frequency (39±14 versus 31±12 bursts/min;
P
=0.020) and lower sympathetic baroreflex sensitivity (−2.83±0.76 versus −3.57±1.19 bursts/100 heartbeats/mm Hg;
P
=0.019) than controls, but burst incidence was not different between groups (56±19 versus 50±20 bursts/100 heartbeats;
P
=0.179). During the cold pressor test, increases in MSNA indices did not differ between groups (
P
=0.135–0.998), but patients had a smaller increase in diastolic BP (Δ4±6 versus Δ14±11 mm Hg;
P
<0.001) compared with controls.

Conclusions:
Despite augmented resting MSNA burst frequency, burst incidence was not significantly different between groups, and sympathetic baroreflex sensitivity was reduced in patients with HFpEF. Furthermore, patients had preserved sympathetic reactivity but attenuated diastolic BP responses during the cold pressor test. These data suggest that, during physiological stress, sympathetic reactivity is intact, but the peripheral pathway for sympathetic vasoconstriction may be impaired in HFpEF.
Validity of Modified STOP-Bang Questionnaire as a Screening Tool for Obstructive Sleep Apnea
Authors: Lee Min-Ki , Choi Ji Ho , Lee Jae Yong 
Published: February 2024

Objectives: The aim of this study was to evaluate the validity of a modified STOP-Bang questionnaire with different body mass index reference as a screening tool for obstructive sleep apnea in Korean population. Methods: The medical records of 1417 participants who underwent overnight Level I polysomnography were retrospectively analyzed. Predictive parameters were calculated for each of the 3 groups classified by obstructive sleep apnea severity with a cut-off value of 3 or 4. Responses to modified and traditional questionnaires were comparatively analyzed by receiver-operator characteristic curves and area under the receiver-operator characteristic curves. Results: The optimal cut-off values of the modified and traditional questionnaires were both 3.5. The area under the receiver-operator characteristic curve of modified STOP-Bang questionnaire for any obstructive sleep apnea group was 0.786 ± 0.018, which was significantly higher than that of the traditional questionnaire. The modified STOP-Bang questionnaire with a cut-off value ≥4 showed significantly higher sensitivity than the traditional one for any obstructive sleep apnea group. The diagnostic accuracy of the modified questionnaire was also significantly higher for the any obstructive sleep apnea group when the cut-off value was 4. Conclusion: The modified STOP-Bang questionnaire, with a cut-off value of 4, can be used as an alternative to the traditional screening tool for the Korean population.
Data from four consecutive cohorts of students in Australia (2019–2022) show the impact of the COVID-19 pandemic on domestic and international university students’ mental health
Authors: Dingle Genevieve A , Han Rong , Alhadad Sakinah SJ , Beckman Emma , Bentley Sarah V , Gomersall Sjaan R , Hides Leanne , Maccallum Fiona , McKimmie Blake M , Rossa Kalina , Smith Simon S , Walter Zoe C , Williams Elyse , Wright Olivia 
Published: February 2024

Introduction: COVID-19 and related travel and social restrictions caused significant stress for university students in Australia and globally. Learning quickly moved online and many students (particularly international students) were separated from social and economic support. This study examined the impact of the pandemic from pre-pandemic (2019) to the COVID-19 Omicron wave (2022) on domestic and international students’ mental health. Methods: Participants were 1540 students (72% females, 28% international) in four first-year cohorts (2019, 2020, 2021, 2022). We screened for mental health concerns (% positive) and symptom scores for depression, anxiety and somatic distress using the PsyCheck, and general wellbeing using the Warwick–Edinburgh Mental Well-being scale. Results: From pre-COVID (2019) to the first wave of COVID-19 (2020), the proportion of students screening positive for mental health problems rose in both domestic students (66–76%) and international students (46–67%). Depression symptoms and wellbeing were worse in 2020 than in 2019, 2021 and 2022. Anxiety symptoms increased from 2019 to 2020 and continued to rise in 2021 and 2022. Somatic symptoms did not show an effect of cohort. Contrary to expectations, domestic students reported higher distress and lower wellbeing than international students across cohorts. Conclusion: The pandemic was associated with a marked increase in psychological distress in first-year university students, not all of which settled with the easing of restrictions. Post-pandemic recovery in the Australian university sector must include university-wide access to mental health information and support for incoming students.
Access to inpatient mood management services after stroke in Australian acute and rehabilitation hospitals
Authors: Hancock Shaun L , Purvis Tara , Thayabaranathan Tharshanah , Stolwyk Rene , Cameron Jan , Dalli Lachlan L , Reyneke Megan , Kilkenny Monique F , Hill Kelvin , Cadilhac Dominique A 
Published: February 2024

Objective Post-stroke mental health impairments are common, but under-assessed and under-treated. We aim to describe trends in the provision of mood management to patients with stroke, and describe factors associated with adoption of national mood management recommendations for stroke within Australian hospitals. Design Secondary analysis of cross-sectional data from the biennial Stroke Foundation Audit Program. Setting Participating acute (2011–2021) and rehabilitation hospitals (2012–2020) in Australia. Participants In the acute audit, 22,937 stroke cases were included from 133 hospitals. In the rehabilitation audit, 15,891 stroke cases were included from 127 hospitals. Main measures Hospital- and patient-level mood management processes. Results Among 133 acute hospitals (22,937 stroke episodes), improvements were made between 2011 and 2021 in utilization of mood screening (17% [2011], 33% [2021]; p < 0.001) and access to psychologists during hospital stay (18% [2011], 45% [2021]; p < 0.001). There was no change in access to a psychologist among those with a mood impairment ( p = 0.34). Among 127 rehabilitation hospitals (15,891 stroke episodes) improvements were observed for mood screening (35% [2012], 61% [2020]; p < 0.001), and access to a psychologist during hospital stay (38% [2012], 68% [2020]; p < 0.001) and among those with a mood-impairment (30% [2012], 50% [2020]; p < 0.001). Factors associated with receiving mood management processes included: younger age, not requiring an interpreter and longer length of stay. Conclusions Adherence to mood management recommendations has improved over 10 years within Australian hospitals. Those aged over 65, requiring an interpreter, or with shorter hospital stays are at risk of missing out on appropriate mood management.
A qualitative exploration of an autism-specific self-compassion program: The ASPAA
Authors: Edwards Chris , Gibbs Vicki , Love Abigail M A , Brown Lydia , Cai Ru Ying 
Published: February 2024

As mental health concerns coupled with inadequate supports have been described as reaching crisis proportions in autistic people, there is a pressing need for accessible and effective support systems. While self-compassion has shown various benefits in the general population, its application in supporting autistic individuals remains limited. This study investigated the experiences of 39 autistic adults who participated in an autism-specific online self-compassion program. The program included a series of five modules which incorporated psychoeducation, meditation, and self-reflective exercises that were completed over a 5-week period. Qualitative data was collected through weekly check-ins and a post-program survey, which underwent thematic analysis through the lens of an autistic researcher resulting in four key themes: the positive impact of self-compassion, challenges faced during the program, recognizing self-compassion as a journey, and the value of program adaptations. These findings shed light on the experiences of autistic adults engaging with self-compassion interventions, highlighting both the benefits and barriers they encountered. The study underscores the importance of developing tailored interventions that consider the unique needs and perspectives of autistic individuals to promote improved mental health outcomes and foster inclusivity. Lay abstract Autistic people often struggle to find the right support for their mental health. We wanted to change that by trying a new approach to help autistic adults with their emotions and well-being. We focused on something called “self-compassion,” which is a way of being kind and understanding toward ourselves. This approach has worked well for many people, but we didn’t know if it would work for autistic individuals. We invited 39 autistic adults to join an online program that taught them about self-compassion. The program lasted 5 weeks and included educational materials, meditation exercises, and self-reflection activities. We asked the participants for feedback each week and at the end of the program. From their responses, we discovered four important things. First, self-compassion had a big positive impact on the well-being of autistic adults. Second, they faced some challenges during the program. Third, they saw self-compassion as a journey that takes time and practice. Finally, they described how they valued changes to help autistic people engage with the program. Our findings show that self-compassion can really help autistic adults. We learned about the benefits they experienced and the difficulties they faced. Most importantly, we found that personalized support is crucial for autistic individuals. By creating programs that consider their specific needs, we can improve their mental health and make their lives better.
Percutaneous Pulmonary Thrombectomy Beyond Acute Pulmonary Embolism: Removing Organized Thrombus in Subacute Massive Pulmonary Embolism
Authors: Tébar Márquez Daniel , Jurado-Román Alfonso , Galeote Guillermo , Jiménez-Valero Santiago , García Muñoz Andoni , Lorenzo Hernández Alicia , Angélica Rivera Núñez María , Alcolea Batres Sergio , Moreno Raúl 
Published: February 2024

Subacute massive pulmonary embolism is an uncommon manifestation of severe pulmonary embolism associated with poor prognosis. Given the chronicity of the thrombi, standard medical treatment may not be effective. We present a case where mechanical thrombectomy using thromboaspiration catheter was effective, resulting in clinical improvement following the extraction of a large amount of thrombus. Clinical Impact Mechanical thrombectomy using a thromboaspiration catheter can be an effective alternative in the treatment of subacute pulmonary embolism.
Yoga Therapy as an Intervention to Improve Patient-Reported Outcomes Among Adults After Treatment for Cancer: Preliminary Findings From a Trial Using Single-Subject Experimental Design
Authors: Brunet Jennifer , Hussien Julia , Pitman Anne , Wurz Amanda , Conte Ellen , Polskaia Nadia , Seely Dugald 
Published: February 2024

Background: Cancer is a chronic condition associated with a substantial symptom burden, which can impair recovery after treatment. Investigating interventions with potential to improve self-reported disease and/or treatment effects—known as patient-reported outcomes (PROs)—is paramount to inform cancer care. The objective of this study was to evaluate the effects of a yoga therapy (YT) intervention on key PROs (ie, cancer-related fatigue, anxiety, cognitive function, depression, stress, quality of life [QoL]) among adults after treatment for cancer. Methods: Data from 20 adults ( Mage = 55.74 years, 85% female; Mtime since diagnosis = 2.83 years) who had completed treatment for cancer were analyzed for this study. In this single-subject exploratory experimental study, the YT intervention comprised a 1:1 YT session (ie, 1 participant with 1 yoga therapist) followed by 6 weekly small (ie, 2–3 participants) group YT sessions. Group sessions were facilitated by the same yoga therapist who delivered participants’ 1:1 session to ensure an in-depth personalized approach. PROs were assessed before (ie, pre-intervention) and after the 1:1 YT session (ie, during the intervention), as well as after the last group YT session (ie, post-intervention). Hierarchical linear modeling was used to analyze the data. Results: Participants showed improvements in cancer-related fatigue, state anxiety, trait anxiety, perceived cognitive impairments, impacts of perceived cognitive impairments on QoL, and 1 dimension of QoL (ie, functional wellbeing) over time. Notably, cancer-related fatigue and state anxiety increased immediately after the 1:1 session, but showed greater improvements over time afterward (ie, during the intervention phase). No changes were observed for the remaining PROs. Conclusion: Although results require confirmation in future trials, this study highlights the importance of continuing to investigate YT as an intervention to enhance important PROs (ie, cancer-related fatigue and state anxiety) after treatment for cancer. More research is needed to identify additional beneficial effects and factors that influence participants’ responses to 1:1 and group YT (ie, moderators and mediators). Registration number: ISRCTN64763228 Date of registration: December 12, 2021. This trial was registered retrospectively. URL of trial registry record: https://www.isrctn.com/ISRCTN64763228 Published Protocol: Brunet, J., Wurz, A., Hussien, J., Pitman, A., Conte, E., Ennis, J. K., . . . & Seely, D. (2022). Exploring the Effects of Yoga Therapy on Heart Rate Variability and Patient-Reported Outcomes After Cancer Treatment: A Study Protocol. Integrative Cancer Therapies, 21, 15347354221075576.
Injuries in elite football (soccer) academy: A 4-year observational cohort study of five categories and 515 players
Authors: Pulici L , Randelli P , Pellegrini A , Zago M , Bellistri G , Niccolai R , Galli M , Dellasette E , Tosi L , Volpi P 
Published: February 2024

Background Youth football (soccer) players in professional teams face a higher likelihood of injury compared to adults. The interplay between football and injury hinges on the contextual environment. Despite this, a gap in knowledge persists regarding the epidemiology within Italian elite football academies. Purpose Assessing injury incidence and distribution in an Italian professional football academy ( n = 515 from U14 to U18) during match and training to understand injury incidence, severity, types, and related factors. Study design Observational cohort study. Methods A descriptive epidemiological study was conducted in a football academy (Campionato Nazionale Serie A) from July 2014 to June 2018. We analyzed data from 515 players divided into five age categories (U14 to U18). Injury occurrence was monitored using a custom data reporting tool adhering to FIFA and UEFA injury surveillance protocols. Injury incidence was calculated as the number of injuries/1000 h of exposure. Injury distribution was classified according to severity, location, type, playing position, and period of injuries across different age categories. Results Eight hundred thirty-two injuries were documented with 4.7 injuries/1000 h of training, 12.4 injuries/1000 h of match and 5.9 injuries/1000 h of total exposure. The months with the lowest number of injuries were June, July, and August ( p < .019). Of all injuries, 430 (51.7%) were caused by trauma, while overuse contributed to 402 injuries (48.3%). Conclusion Findings revealed that injury epidemiology within an Italian professional football academy can be compared to other European countries. These data can serve as a reference for clinicians and sports scientists.