bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Epley Maneuver versus Betahistine in Treatment of Benign Paroxysmal Positional Vertigo
Authors: Dawood Mohammed Radef 
Published: December 2023

Background:
Benign paroxysmal positional vertigo (BPPV) is considered the most common cause of vertigo. The necessity for early and effective management resulted in the improvement of the patient’s life quality. The objective was to compare the efficacy between Epley’s maneuver and betahistine dihydrochloride in BPPV treatment.

Patients and Methods:
A prospective follow-up comparative study on 60 patients with BPPV, who diagnosed with a positive Dix–Hallpike test, were divided equally and randomly into two groups; Group “A” treated with Epley’s maneuver and Group “B” treated with betahistine dihydrochloride. The efficacy of each modality was assessed, regarding the sense of vertigo and its associated symptoms, data of vertigo scales as the Visual Analog Scale (VAS), and Dizziness Handicap Inventory (DHI).

Results:
There were 23 males (38.33%), and 37 females (61.66%), with mean age (54 ± 7.521) years. The total vertigo improvement was (78.33%); being (93.33%) in group “A” and (63.33%) in group “B”, nausea and vomiting symptoms improvement was (76.66%) in group “A”, and (70%) in group “B”. The baseline VAS score in Group “A” (7.69 ± 1.235 SD) and in Group “B” (6.35 ± 3.267 SD) after treatment improved to 0.56 ± 0.731 SD and 1.86 ± 1.375 SD, respectively, as well as the baseline DHI value in Group “A” (51.86 ± 23.583 SD) and in Group “B” (49.37 ± 18.152 SD) then improved to 2.31 ± 3.986 and 7.98 ± 9.512 SD, respectively.

Conclusions:
The Epley maneuver was more effective and “statistically significant” in relieving vertigo, and both the VAS and DHI scales compared to betahistine, while regarding associated nausea and vomiting symptoms, it shows no statically significant difference.
Takotsubo Cardiomyopathy Due to Electric Shock by Home Appliance; An Unusual Finding in Day-to-day Life
Authors: Manuja Nishtha , Saboo Keyur , Daiya Varun , Kumar Jayanth , Kumar Sunil , Acharya Sourya 
Published: December 2023

Abstract
Takotsubo cardiomyopathy or stress cardiomyopathy is a sudden transient cardiac syndrome that shows left ventricular apical akinesis and mimics acute coronary syndrome. Coronary flow is normal. We describe the case of a 28-year-old male who encountered an electric shock at home, and after that, developed acute chest pain and palpitations. His cardiac markers were raised, and his electrocardiogram revealed myocardial ischemia. The epicardial flow was found to be normal after coronary angiography. Takotsubo cardiomyopathy was identified as the cause.
Understanding the Position of Beta-blockers in the Management of Hypertension among Patients with Different Clinical Comorbidities: An Expert Opinion of Cardiologists from India
Authors: Kumar Arram Sreenivas , Jadhav Uday , Solanki Dharmesh , Hazra Prakash K. , Alexander Thomas , Biswas Kaushik , Revankar Santosh , Ghatge Shweta , Kumar Neeraj 
Published: December 2023

Abstract

Background:
Elevated blood pressure (BP) increases the risk of cardiovascular mortality, underscoring the vital importance of effective management in individuals with hypertension (HTN) and cardiovascular disease. However, lack of clear guidance on the utilization of the new beta-blockers has caused hesitation among doctors in using them effectively. The objective of this expert opinion was to understand the role and current position of beta-blockers in the management of patients with HTN and different clinical comorbidities.

Methods:
A collective of 828 cardiologists throughout India were invited to participate in an online survey and virtual meetings. Their clinical insights were gathered on approaches in managing these patients and their understanding of the role of beta-blockers.

Results:
The panel of experts recommended that in patients with HTN and angina, the BP target should be 130/80 mmHg (40.70%), and the use of a combination of telmisartan and cardio-selective beta-blockers should be used to lower BP (63.29%). A combination of telmisartan and a beta-1 blocker was recommended for effective BP control and structural regression of left ventricular hypertrophy (52.78%). For intensive BP control, combination therapy of telmisartan and beta-blockers should be used in patients with HTN and atrial fibrillation (59.18%). The panel of experts opined (60.02%) that different BP targets should be considered for different stroke subtypes. Telmisartan (44.44%) and selective beta-1 blockers (29.35%) are recommended to manage BP variability in patients with HTN and recurrent stroke.

Conclusion:
In patients with HTN and cardiovascular disease, individualized decision-making is necessary for beta-blocker use in HTN management. Selective beta-blockers should be considered first-line therapy or combined with telmisartan when indicated.
A Study of the Role of Prognostic Laboratory Parameters among COVID-19 Patients: A Retrospective Cohort Study
Authors: Parikh Nirav , Patel Hasmukh , Chauhan Ankit 
Published: December 2023

Abstract

Background:
The emergence and spread of the coronavirus disease 2019 (COVID-19) pandemic presents an immense challenge to public health and has resulted in a dramatic loss of human life worldwide. Thus, diagnosis and identification of clinical laboratory parameters associated with the disease become crucial in critical cases, requiring intensive care management.

Aim:
To investigate clinical laboratory parameters that may be associated with severe or critical COVID-19 disease patients, particularly those requiring intensive care management.

Materials and Methods:
A retrospective cohort study was conducted at the U. N. Mehta Institute of Cardiology and Research Institute, Ahmedabad, Gujarat. A total of 1460 COVID-19-positive patients (aged 18 years and older) requiring admission to the intensive care unit were selected from April 3 to May 23, 2021, were enrolled, and were diagnostically monitored. Patients were evaluated based on their demographics. A Welsch t-test was used to calculate the progression in the mean difference among inflammatory and/or thromboembolic markers.

Results:
We analyzed and examined certain laboratory parameters across the timeline and compared survival (Group 1) and nonsurvival (Group 2). All the factors were higher in Group 2 compared to Group 1, except for C-reactive protein-Q (CRP-Q), which decreased in both groups, but in Group 1, there was a further decrease in CRP-Q value as compared to Group 2 on retest day.

Conclusion:
The results of the current study provide clinical value for prognostic factors associated with COVID-19 and establish the role of laboratory parameters in evaluating disease severity and complications.
Impact of comorbidities and inflammatory markers on mortality of COVID-19 patients
Authors: Karim Azmat , Shameem Mohammad , Talwar Anjana , Talwar Deepak 
Published: December 2023

Background:
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus that causes coronavirus disease 2019 (COVID-19) is a serious global health concern. The severity of the disease can be determined by serologic indicators such as C-reactive protein, lactate dehydrogenase, D-dimer, ferritin, and interleukin-6. (IL-6). Patients with preexisting conditions such as respiratory, cardiovascular, and pulmonary disease could be at risk of adverse outcomes. It is crucial to provide adequate medical care to manage these patients and increase their chances of survival.

Aim:
The study examined the impact of comorbidity and inflammatory markers on the severity and mortality of hospitalised COVID-19 patients.

Materials and Methods:
This retrospective study included 101 COVID-19 patients who had comorbidities and were hospitalised from April 2021 to April 2022.

Results:
Patients with a severe COVID-19 infection could be anticipated to have higher levels of inflammatory markers in their blood. Patients with chronic kidney and coronary artery disease have a worse prognosis than those with other comorbidities (P value <0.001). However, tuberculosis had no statistically significant effect on mortality and showed a minimal chance of death (P value = 0.303). In addition, tocilizumab performed poorly and was ineffective against the COVID-19 treatment. However, ivermectin exhibited a statistically significant probability of survival in COVID-19 patients.

Conclusion:
The inflammatory markers D-dimer, ferritin, and IL-6 were identified as valuable indicators of disease severity. Further, chronic kidney disease and coronary artery disease were identified as risk factors for mortality, while tuberculosis showed potential protective effects. The study showed that higher neutrophil levels were linked to mortality in tocilizumab-treated patients, while ivermectin showed promise in increasing survival rates.
Gauging the knowledge, attitude and practice of interns and dentists about obstructive sleep apnoea—A cross-sectional study
Authors: Chauhan Megha , Chauhan Manish R. , Agrawal Ananya , Chawla Ashokkumar R. 
Published: December 2023

Context:
Obstructive sleep apnoea is less known and lesser practised in dentistry. Dentists often struggle to educate, diagnose or offer treatment to the patient. Hence, the disorder of the patient and the opportunity for the dentist both go unnoticed.

Aim:
To assess the knowledge, attitude and practice regarding aspects of obstructive sleep apnoea among dental practitioners, faculty and interns in India.

Methods and Material:
A self-constructed validated questionnaire was prepared and circulated online among dental interns and professionals in India. Responses received from 237 participants were evaluated and statistically analysed.

Results:
Only questions about diagnosis and symptoms of OSA were correctly answered by more than 50% of the participants. In all other questions, the knowledge was poor. Only 11.4% of respondents felt that they are well equipped to diagnose OSA. The general attitude of the participants was favourable but with poor practice. Only 5.1% of participants were ever involved in the treatment of OSA.

Conclusions:
Given the high prevalence of OSA among the population, along with widespread ignorance among dentists for the same as found in our study, there is an urgent need to spotlight OSA in the dental curriculum at an undergraduate level. To complement this, extensive training and motivation must also be provided so that dental graduates can identify, refer and participate in the treatment of OSA.
Acute kidney injury in birth asphyxiated patients: A cross sectional study at Bahawal Victoria Hospital
Authors: Tounsa Akhtar , Hussain Arif , Hussain Irshad , Tariq Rabia , Saqlain Muhammad , Shaikh Saba A. , Mumtaz Hassan 
Published: December 2023

Background:
The presence of perinatal asphyxia and its severity appear to correlate with increasing incidence of Acute kidney injury (AKI). The objective of this study is to determine the frequency of AKI and its outcome in birth asphyxia.

Methods:
This cross-sectional study was carried out in the Department of Pediatric Medicine from March 2019 to September 2019. A total of 111 newborns with birth asphyxia of gestational age 37–41 weeks were included. Neonates born to mothers having hypertension and diabetes mellitus, patients with congenital kidney anomalies like polycystic kidney disease and renal agenesis, and mothers taking nephrotoxic drugs or any other known cause of AKI like hypovolemic shock were excluded. Urine output (UOP) and final outcome of the patient were also noted. AKI was noted.

Results:
The mean gestational age was 38.29 ± 1.07 weeks. The mean weight of neonates was 3.08 ± 0.31 kg. The frequency of AKI in birth asphyxia was 20 (18.02%) neonates. Complete recovery in AKI patients was seen in 07 (35.0%) and death in 13 (65.0%) patients.

Conclusion:
This study has shown that the frequency of AKI in birth asphyxia was found in 18.02% neonates with complete recovery seen in 35.0% and death in 65.0% patients.
Effect of delamanid on interim outcomes of bacteriological conversion amongst pediatric drug resistant tuberculosis cases in India
Authors: Kalawadia Dhruv , Gandhi Darshini , Dirkhipa Tsering Y. , Jaiswal Akanksha , Shah Daksha , Salve Jyoti , Parmar Malik , Sachdeva Kuldeep S , Bodhanwala Minnie , Shah Ira 
Published: December 2023

Aim:
To determine the bacteriological conversion rate after 6 months of Delamanid (DLM) based treatment in children with drug-resistant tuberculosis (DR-TB) and determine factors associated with bacteriological conversion.

Methods:
This is a descriptive retrospective study done in children between the age of 6-17 years with DR-TB who received DLM-based therapy from October 2018 to May 2021. The drug resistance pattern of TB was detected using Xpert RIF/MTB and phenotypic drug sensitivity testing (DST) on TB-MGIT culture reports. Follow-up sputum TB MGIT culture was carried out monthly after DLM initiation for 6 months. Factors associated with sputum bacteriological conversion such as age, gender, pulmonary TB (PTB) versus disseminated TB, unilateral or bilateral lung involvement, type of DR-TB, prior treatment failure, and type of DR-TB regimen were analyzed.

Results:
Sixty patients received DLM of which two had extrapulmonary TB (EPTB) and sputum conversion could not be assessed. The mean age at presentation was 12.69 ± 3.03 years. Five patients (8.3%) died while on DLM treatment. On follow-up, 8 (13.7%) out of 58 patients had no sputum bacteriological conversion after 6 months of DLM initiation of which three patients were on salvage therapy; 46 (79.3%) had sputum bacteriological conversion within 6 months of DLM initiation.

Conclusion:
Sputum bacteriological conversion rate was almost 80% at the end of 6 months of DLM-based treatment.
Sublobar resection for metachronous stage I second primary non-small cell lung cancer: A single-centre experience
Authors: Yotsumoto Takuma , Fujimori Sakashi , Suzuki Souichiro , Kikunaga Shinichiro , Niitsuma Toru 
Published: December 2023

Introduction:
More patients are developing second primary lung cancer (SPLC). This study aimed to evaluate the impact of the extent of SPLC resection on outcomes.

Material and Methods:
We retrospectively investigated 1,895 patients with lung cancer who underwent pulmonary resection from 2011 to 2018. SPLC was diagnosed using the criteria of Martini and Melamed. Patients with pathological stage I SPLC who underwent lobectomy for first primary lung cancer (FPLC) were included in the study. Outcomes and clinical factors that could affect survival were evaluated.

Results:
Fifty-four patients were eligible for the study. Lobectomy, segmentectomy, or wedge resection was performed for 10, 32, and 12 patients, respectively. Neither overall nor relapse-free survival was significantly different based on the extent of resection for stage I SPLC. Multivariate analysis revealed that interval between FPLC and SPLC of less than 5 years was an independent risk factors for worse relapse-free survival after SPLC resection (interval: hazard ratio, 0.28; P = 0.048). The median interval from prior resection to secondary resection was 68 months.

Conclusions:
Sublobar resection might be a realistic option for stage I SPLC. To realize early detection of SPLC that can undergo radical sublobar resection, the surveillance period after prior resection of FPLC is worth reconsidering.
Pengembangan Bandara Waterbase Pesawat Terbang Laut Sebagai Penunjang Wisata di Pulau Tinabo, Kepulauan Selayar, Sulawesi Selatan
Authors: Sri Yusyarif Idham , Wunas Shirly , Sitepu Ganding 
Published: December 2023

Pariwisata merupakan salah satu bidang strategis penggerak roda perekonomian dengan kontribusi yang besar. Untuk memperkuat pengembangan pariwisata perlu ditunjang oleh akses transportasi yang memadai. Tujuan penelitian ini adalah 1)untuk menganalisis potensi wisata pulau dan potensi pengembangan pesawat terbang l(sea plane) untuk angkutan wisata Pulau Tinabo Besar, 2)menjelaskan kondisi Oseanografi dan Meteorologi yang dapat mendukung penerbangan pesawat terbang laut (sea plane), serta 3)menganalisis dimensi ruang yang layak untuk mengembangkan angkutan wisata pesawat terbang laut di pulau Tinabo Besar Taman Nasional Takabonerate kabupaten Kepulauan Selayar. Sumber data penelitian ini berasal dari dokumentasi BMKG, BPS 2020-2021, dan dari Balai Taman Nasional Takabonerate 2021 serta survei langsung di lokasi penelitian serta wawancara dengan Pengelola Banyuwa Balai Takabonerate, dan API Banyuwangi. Penelitian ini menggunakan analisis secara deskriptif, komparatif dan anlisis spatial. Hasil penelitian menunjukkan bahwa: 1) Pulau Tinabo Besar yang memiliki Taman Nasional Takabonerate sangat berpotensi untuk pengembangan wisata pulau, dan layak untuk pengembangan angkutan wisata berbasis pesawat terbang laut 2) kondisi Oseanografi dan Meteorologi Pulau Tinabo Besar layak diterapkan angkutan wisata berbasis pesawat terbang laut, berdasarkan hasil data BMKG, dan 3) dimensi ruang yang layak untuk mengembangkan angkutan wisata pesawat terbang laut di Pulau Tinabo Besar adalah luas operasi takeoff dan landing Pesawat terbang laut di tambah dengan zona luas zona pemnafaatan Pulau Tinabo besar yaitu 5,06 km2 + 9,73 km2 sehingga total luas wilayah adalah 14,79 km2. Dimesi ruang Pulau Tinabo Besar layak untuk perencanaan tempat landing dan takeoff pesawat terbang laut. Namun untuk dermaga perlu uji coba ketahanan apabila dikembangkan sebagai tempat tambat pesawat terbang laut, serta dilengkapi dengan beberapa peralatan penunjang, seperti alat pemadam kebakaran, alat keselamatan, lampu, kantong angin, dan peningkatan keterampilan personil yang bertugas.
Development Whitefly Pest Population (Bemisia tabaci G.) In Plants Cucumbers in the Pupuan Village, Tegallalang District, Gianyar Regency, Bali
Authors: I Wayan Dirgayana  , Dicky Marsadi  
Published: December 2023

Cucumber ( Cucumis sativus Linn. ) is one plant lots of fresh vegetables consumed Indonesian society . Production your cucumber affected by the attack Whitefly pest ( Bemisia _ tabaci ). study This aim For know the presence of whitefly ( Bemisia tabaci ) on plants cucumbers in the Village Pupuan , District Tegallalang , Regency Gianyar . Study This held with observation or exploration in a way directly on the land plant cucumber . Study using 5 grid plots observation . In each plot, 5 clumps were observed plants , determination plant sample done with method diagonal sampling method . Total plants observed cucumber _ as sampling is 25 clusters plant . Observation held every a week very . Research result shows the Bemesia Pest tabaci are found in the field plant cucumbers at 14 Days After Plant with average number of nymphs 0.4 and imago 0.2 / Plant and Number population pest Bemesia tabaci on plants cucumber increase from observation I arrived _ observation to -VIII
Escenas de contacto del archivo afectivo: fragmentos, búsquedas y sub-versiones de una viejita guerrillera
Authors: Tortosa Paula Inés 
Published: December 2023

Este trabajo se pregunta sobre el vínculo entre afectividad y memoria a partir de la construcción del archivo afectivo de Czury Edith Lamy, mi tía abuela desaparecida en 1977 por la dictadura cívico-eclesiástica- militar en Argentina. Se centra en algunas “escenas de contacto” que exceden la acepción centrada en las prácticas teatrales y amplía el espectro de posibilidades: algunas son provenientes de documentos, testimonios y relatos sobre Czury, y otras surgen a partir de mí experiencia de participación y creación de dispositivos estéticos que conjugan lenguajes de distintas artes escénicas como el teatro, la danza, la performance y la expresión corporal. La metodología toma elementos de la Investigación Acción Participativa y de la autoetnografía. Se realizó un trabajo de campo y se utilizaron tanto fuentes primarias como secundarias. En primer lugar daré cuenta de las escenas de Czury que emergen del silencio y aparecen difusas, fragmentadas y plagadas de “errores”. Luego las que tienen como eje la búsqueda, para finalmente indagar en las que plantean otras (di)versiones de Czury, incluyendo su devenir performer que conecta con la propuesta performática que despliego en el Relato Situado. A partir del trabajo realizado se produjeron formas de “encuirar” las memorias de Czury que se narraron en forma encuerpada en escenas inexactas, sensoriales y contrahegemónicas. A su vez, se pudo visibilizar el carácter político de los afectos en tanto son capaces de generar acciones, crear otros sentidos y temporalidades.
Biocha Soil Amendment: Effect on Soil, Crop Performance, and Diseases Resistance
Authors: Amare Ermias Misganaw 
Published: December 2023

One of the main challenges facing developing countries is an ever-increasing gap between population growth and food supply. Diseases, insects, and weeds decrease the production of crops worldwide by 36%. Hence, control of crop pests contributes to increased crop production. Organic amendments to the soil have direct impacts on crop productivity and plant health as it enhances soil fertility, water, and nutrient retention and plant disease defense mechanisms. Biochar is an important organic amendment. It is produced by the pyrolysis process, whereby organic substances are broken down at higher temperatures in low oxygen conditions. Biohar improved soil nutrient availability and water retention capacity, and induced plant resistance against broad ranges of plant pathogenic organisms including fungi, nematodes, and bacteria. Biochar soil amendment also enhances root-associated microbes such as flavobacterium and arbuscular mycorrhizae. Biochar amendments can increase soil essential nutrients for crop productivity and suppress plant pathogens. Suppression of plant pathogens is attributed to the stimulation of beneficial soil microbes, providing nutrients, and inducing plant defense. The objectives of the review are to depict the importance of biochar soil amendment on crop performance, disease resistance, and soil properties.
Design of an E-Nose Detector for Contaminated Gas in Cow Farming Waste
Authors: Rusdianto Andrew Setiawan , Amilia Winda , Malik Laila Adhani Putri 
Published: December 2023

Cattle farm waste is organic waste produced by the livestock industry in the form of feces and can emit gases that cause air pollution. Cow dung contamination can cause environmental problems, disturbing humans and livestock. Hazardous gases produced from the decomposition of livestock manure, namely methane (CH4), sulfur dioxide (SO2), ammonia (NH3), and hydrogen sulfide (H2S), can cause respiratory diseases, deplete ozone and contribute to the greenhouse effect. Based on these problems, measuring gas levels using an Electronic Nose (E-Nose) tool capable of detecting harmful gases in livestock pens is necessary. The E-nose is a device that mimics the human nose and consists of several gas sensors that can detect environmental odors. The design of the detection and measurement of toxic gases using an electronic nose in this study adopts the Internet of Things (IoT) concept using the Arduino Uno and ESP8266 microcontrollers and MQ-4, MQ-136, and MQ-137 gas sensors to read levels of pollutant gas in units of ppm with an average of 46.25 ppm for the MQ-4 sensor, 1.86 ppm for the MQ-136 sensor, and 4.97 ppm for the MQ-137. The sensors were subjected to functional tests consisting of validity testing, resulting in a calculated r value of 1, meaning that each gas sensor performs its measurement function correctly or validly. The reliability test of the MQ-4 sensor is 0.00, the MQ-136 sensor is 2.442× 10-15, and the MQ-137 sensor is 1.554× 10-15, which means that the data reading from each gas sensor is unstable, less accurate, or unreliable compared to secondary data. However, the designed E-Nose tool can work well and improve farmers' performance in their daily work.