bluuebunny/crossref_metadata_2025_split huggingface dataset:
AMMONIA (FORAMINIFERA) IN LONG ISLAND SOUND (USA): MOLECULAR AND MORPHOLOGICAL DIVERSITY
Authors: Goetz Eleanor J. , Yan Allison , Hull Pincelli M. , Thomas Ellen 
Published: January 2025

ABSTRACT
Ammonia is one of the best studied and earliest recognized foraminifera, yet genetic and morphological data from the northeastern USA are scarce. We present the first molecular data of Ammonia phylotypes collected in Long Island Sound (LIS), USA (2022–2023), identified using SSU rDNA. We identified four species from eight sites, using genetic and morphological data: A. veneta (T1), A. confertitesta (T6), A. advena (T7), and A. sobrina (T9). Morphological analysis was challenging due to high intraspecies variation and the occurrence of partially decalcified and deformed specimens. We found that A. confertitesta was the most abundant taxon in both our molecular and morphological data, followed by A. veneta, A. advena, and A. sobrina. Ammonia confertitesta was originally described from Shandung Province (China) but recognized as an invasive species in Europe and British Columbia (CA). This group, previously unknown from the East Coast (USA), is the dominant Ammonia taxon in LIS.
Cimentación para Torre de Observación en la Parroquia de Limoncocha, un Reto en la Reserva Natural y Faunística. Aplicación de cálculos de geotecnia y cimentaciones profundas
Authors: Durán Sánchez Fernando Antonio , Macas Chanaluisa Diego Ronaldo , Arroba Giraldo Andrea Mariela , Gómez Gómez Byron Wladimir 
Published: January 2025

El presente Artículo trata de utilizar parámetros de diseño establecidos en normativas nacionales como la Norma Ecuatoriana de la Construcción NEC-2015; normas internacionales como NTC-Cimentaciones de la CDMX (2017) y Norma N·PRY·CAR·8·02·001, Ejecución de Proyectos de Cimentaciones Profundas, las cuales brindan recomendaciones necesarias para el diseño estructural de cimentaciones de forma analítica destacándose el desarrollo de cálculos que garantizan la seguridad de la edificación con el fin de evidenciar cual será el comportamiento estructural del sistema edificado analizado teniendo como base que dicha estructura está configurada por medio de pórticos y cimentación de hormigón armado anclado a un grupo de pilotes pre excavados, que garantizara el funcionamiento de esta Torre de Observación además de que provocara en funcionamiento óptimo ante un sismo ya que su desempeño garantiza que es una estructura segura ubicándose su punto de capacidad entre el punto B e IO que quiere decir que luego de un sismo El nivel de desempeño de la estructura es el adecuado decir la Torre podría tener daños estructurales leves luego de un evento sísmico fuerte, además por tratarse de una estructura con arrostramientos sus deformaciones serán mínimas y no se prevé pandeo, y si existen replicas sísmicas esta torre no sufrirá el colapso, sumado a que tendrá una estabilidad estructural adecuada ante excitaciones por cargas de vientos probables sumado a que su impacto ambiental será mínimo lo que permite su implementación constructiva dentro del área de la reserva bilógica de Limoncocha..
Percepción sobre la brecha salarial de género en la ciudad de Tarija – Bolivia
Authors: Vásquez Fernández Bernardino Jesús 
Published: January 2025

La brecha salarial de género se define como la diferencia existente entre el salario medio de los hombres y el salario medio de las mujeres, en donde la mujer gana menos que el hombre por hacer el mismo trabajo, generalmente ocasionado por desigualdades en el trabajo, educación y responsabilidades familiares que tienen las mujeres. La investigación busca determinar si la brecha salarial presenta diferencias significativas en la ciudad de Tarija, en base a sus principales causas, efectos y alternativas para reducirla. El estudio aplicó mil encuestas de opinión, mediante un muestro no probabilístico por cuotas de sexo y edad, en la ciudad de Tarija en Bolivia, en los meses de abril y mayo de 2019. Los resultados más importantes señalan que la brecha salarial entre hombres y mujeres es del 32%. El ingreso promedio de los hombres es de Bs 3304 al mes (aproximadamente USD$454), mientras que el ingreso promedio de las mujeres es de Bs 2495 al mes (aproximadamente USD$358). Los principales causantes son la antigüedad laboral, la formación profesional y la experiencia laboral. Las mujeres dedican más horas a las actividades domésticas y cuidados familiares que los hombres. Las principales consecuencias son la limitación de las mujeres para tomar decisiones, mayor dependencia de otras personas, baja autoestima, pensiones más bajas y empobrecimiento. Entre las medidas para reducir la brecha están la promoción de las mujeres a puestos directivos, políticas retributivas más claras y la promoción de una labor más equitativa en los trabajos domésticos del hogar.
‘Story Bird’ As A Platform For Writing Classroom
Authors: Aminah Aminah , Syahputra M. 
Published: January 2025

Writing is a process of transferring your ideas in written form. It is not an easy thing to do because there are some rules that we should follow in order to make our messages deliver to the reader. The aim of this study is to investigate the use of Story Bird application in teaching writing. This research belongs to descriptive library research by analysis the content of documents. It can be seen that storybird as a web 2.0 tool is really appropriate to use in writing classroom. It offers some advantages including the allowing collaborative work, easy to organize work, allowing students to publish their work that can increase their motivation to write. This research is recommended to use in teaching writing.
Perceptions of Use of Names, Recognition of Roles, and Teamwork After Labeling Surgical Caps
Authors: Wong Becky J. , Nassar Aussama K. , Earley Michelle , Chen Ling , Roman-Micek Teresa , Wald Samuel H. , Shanafelt Tait D. , Goldhaber-Fiebert Sara N. 
Published: November 2023

ImportanceCommunication failures in perioperative areas are common and have negative outcomes for both patients and clinicians. Names and roles of teammates are difficult to remember or discern contributing to suboptimal communication, yet the utility of labeled surgical caps with names and roles for enhancing perceived teamwork and connection is not well studied.ObjectiveTo evaluate the use of labeled surgical caps in name use and role recognition, as well as teamwork and connection, among interprofessional perioperative teammates.Design, Setting, and ParticipantsIn this quality improvement study, caps labeled with names and roles were distributed to 967 interprofessional perioperative clinicians, along with preimplementation and 6-month postimplementation surveys. Conducted between July 8, 2021, and June 25, 2022, at a single large, academic, quaternary health care center in the US, the study comprised surgeons, anesthesiologists, trainees, and all interprofessional hospital staff who work in adult general surgery perioperative areas.InterventionLabeled surgical caps were offered cost-free, although not mandatory, to each interested clinician.Main Outcome and MeasureQuantitative survey of self-reported frequency for name use and role recognition as well as postimplementation sense of teamwork and connection. The surveys also elicited free response comments.ResultsOf the 1483 eligible perioperative clinicians, 967 (65%; 387 physicians and 580 nonphysician staff; 58% female) completed preimplementation surveys and received labeled caps, and 243 of these individuals (51% of physicians and 8% of staff) completed postimplementation surveys. Pre-post results were limited to physicians, due to the low postsurvey staff response rate. The odds of participants reporting that they were often called by their name increased after receiving a labeled cap (adjusted odds ratio [AOR], 13.37; 95% CI, 8.18-21.86). On postsurveys, participants reported that caps with names and roles substantially improved teamwork (80%) and connection (79%) with teammates. Participants who reported an increased frequency of being called by their name had higher odds for reporting improved teamwork (AOR, 3.46; 95% CI, 1.91-6.26) and connection with teammates (AOR, 3.21; 95% CI, 1.76-5.84). Free response comments supported the quantitative data that labeled caps facilitated knowing teammates’ names and roles and fostered a climate of wellness, teamwork, inclusion, and patient safety.Conclusions and RelevanceThe findings of this quality improvement study performed with interprofessional teammates suggest that organizationally sponsored labeled surgical caps was associated with improved teamwork, indicated by increased name use and role recognition in perioperative areas.
Brain Volume in Fetal Alcohol Spectrum Disorders Over a 20-Year Span
Authors: Pfefferbaum Adolf , Sullivan Edith V. , Pohl Kilian M. , Bischoff-Grethe Amanda , Stoner Susan A. , Moore Eileen M. , Riley Edward P. 
Published: November 2023

ImportanceAnomalous brain development and mental health problems are prevalent in fetal alcohol spectrum disorders (FASD), but there is a paucity of longitudinal brain imaging research into adulthood. This study presents long-term follow-up of brain volumetrics in a cohort of participants with FASD.ObjectiveTo test whether brain tissue declines faster with aging in individuals with FASD compared with control participants.Design, Setting, and ParticipantsThis cohort study used magnetic resonance imaging (MRI) data collected from individuals with FASD and control individuals (age 13-37 years at first magnetic resonance imaging [MRI1] acquired 1997-2000) compared with data collected 20 years later (MRI2; 2018-2021). Participants were recruited for MRI1 through the University of Washington Fetal Alcohol Syndrome (FAS) Follow-Up Study. For MRI2, former participants were recruited by the University of Washington Fetal Alcohol and Drug Unit. Data were analyzed from October 2022 to August 2023.Main Outcomes and MeasuresIntracranial volume (ICV) and regional cortical and cerebellar gray matter, white matter, and cerebrospinal fluid volumes were quantified automatically and analyzed, with group and sex as between-participant factors and age as a within-participant variable.ResultsOf 174 individuals with MRI1 data, 48 refused participation, 36 were unavailable, and 24 could not be located. The remaining 66 individuals (37.9%) were rescanned for MRI2, including 26 controls, 18 individuals with nondysmorphic heavily exposed fetal alcohol effects (FAE; diagnosed prior to MRI1), and 22 individuals with FAS. Mean (SD) age was 22.9 (5.6) years at MRI1 and 44.7 (6.5) years at MRI2, and 35 participants (53%) were male. The FAE and FAS groups exhibited enduring stepped volume deficits at MRI1 and MRI2; volumes among control participants were greater than among participants with FAE, which were greater than volumes among participants with FAS (eg, mean [SD] ICV: control, 1462.3 [119.3] cc at MRI1 and 1465.4 [129.4] cc at MRI2; FAE, 1375.6 [134.1] cc at MRI1 and 1371.7 [120.3] cc at MRI2; FAS, 1297.3 [163.0] cc at MRI1 and 1292.7 [172.1] cc at MRI2), without diagnosis-by-age interactions. Despite these persistent volume deficits, the FAE participants and FAS participants showed patterns of neurodevelopment within reference ranges: increase in white matter and decrease in gray matter of the cortex and decrease in white matter and increase in gray matter of the cerebellum.Conclusions and RelevanceThe findings of this cohort study support a nonaccelerating enduring, brain structural dysmorphic spectrum following prenatal alcohol exposure and a diagnostic distinction based on the degree of dysmorphia. FASD was not a progressive brain structural disorder by middle age, but whether accelerated decline occurs in later years remains to be determined.
Preeclampsia and Long-Term Risk of Venous Thromboembolism
Authors: Havers-Borgersen Eva , Butt Jawad H. , Johansen Marianne , Petersen Olav Bjørn , Ekelund Charlotte Kvist , Rode Line , Olesen Jonas Bjerring , Køber Lars , Fosbøl Emil L. 
Published: November 2023

ImportanceAs venous thromboembolism (VTE) remains one of the leading causes of maternal mortality, identifying women at increased risk of VTE is of great importance. Preeclampsia is a pregnancy-induced hypertensive disorder with generalized endothelial dysfunction. Some studies suggest that preeclampsia is associated with an increased risk of VTE, but much controversy exists.ObjectiveTo examine the association between preeclampsia and the risk of VTE during pregnancy, during the puerperium, and after the puerperium.Design, Setting, and ParticipantsThis observational cohort study used Danish nationwide registries to identify all eligible primiparous women who gave birth in Denmark from January 1, 1997, to December 31, 2016. The women were followed up from primiparous pregnancy to incident VTE, emigration, death, or the end of the study (December 31, 2016). Statistical analyses were carried out from January to May 2023.ExposurePreeclampsia during primiparous pregnancy.Main Outcomes and MeasureThe main outcome was incident VTE, and the secondary outcome was all-cause mortality.ResultsA total of 522 545 primiparous women (median age, 28 years [IQR, 25-31 years]) were included, and 23 330 (4.5%) received a diagnosis of preeclampsia. Women with preeclampsia were of similar age to women without preeclampsia but had a higher burden of comorbidities. During a median follow-up of 10.2 years (IQR, 5.2-15.4 years), preeclampsia was associated with a higher incidence of VTE compared with no preeclampsia (incidence rate, 1.23 [95% CI, 1.10-1.38] vs 0.85 [95% CI, 0.82-0.87] per 1000 patient-years, corresponding to an unadjusted hazard ratio [HR] of 1.45 [95% CI, 1.29-1.63] and an adjusted HR of 1.43 [95% CI, 1.27-1.61]). When stratified according to the subcategories of VTE, preeclampsia was associated with an increased rate of deep vein thrombosis (unadjusted HR, 1.51 [95% CI, 1.32-1.72] and adjusted HR, 1.49 [95% CI, 1.31-1.70]) as well as pulmonary embolism (unadjusted HR, 1.39 [95% CI, 1.09-1.76]; adjusted HR, 1.36 [95% CI, 1.08-1.73]). These findings held true in landmark analyses during pregnancy, during the puerperium, and after the puerperium.Conclusions and RelevanceThis cohort study suggests that preeclampsia was associated with a significantly increased risk of VTE during pregnancy, during the puerperium, and after the puerperium, even after thorough adjustment. Future studies should address how to improve the clinical management of women with a history of preeclampsia to prevent VTE.
Modular Aptamer Switches for the Continuous Optical Detection of Small‐Molecule Analytes in Complex Media
Authors: Hariri Amani A. , Cartwright Alyssa P. , Dory Constantin , Gidi Yasser , Yee Steven , Thompson Ian A. P. , Fu Kaiyu X. , Yang Kiyoul , Wu Diana , Maganzini Nicolò , Feagin Trevor , Young Brian E. , Afshar Behrad Habib , Eisenstein Michael , Digonnet Michel J. F. , Vuckovic Jelena , Soh H. Tom 
Published: November 2023

AbstractAptamers are a promising class of affinity reagents because signal transduction mechanisms can be built into the reagent, so that they can directly produce a physically measurable output signal upon target binding. However, endowing the signal transduction functionality into an aptamer remains a trial‐and‐error process that can compromise its affinity or specificity and typically requires knowledge of the ligand binding domain or its structure. In this work, a design architecture that can convert an existing aptamer into a “reversible aptamer switch” whose kinetic and thermodynamic properties can be tuned without a priori knowledge of the ligand binding domain or its structure is described. Finally, by combining these aptamer switches with evanescent‐field‐based optical detection hardware that minimizes sample autofluorescence, this study demonstrates the first optical biosensor system that can continuously measure multiple biomarkers (dopamine and cortisol) in complex samples (artificial cerebrospinal fluid and undiluted plasma) with second and subsecond‐scale time responses at physiologically relevant concentration ranges.
Photoelectrons Sequentially Regulate Antibacterial Activity and Osseointegration of Titanium Implants
Authors: Tang Yufei , Wang Kai , Wu Bingfeng , Yao Keyi , Feng Shuqi , Zhou Xuemei , Xiang Lin 
Published: November 2023

AbstractTitanium implants are widely used ; however, implantation occasionally fails due to infections during the surgery or poor osseointegration after the surgery. To solve the problem, an intelligent functional surface on titanium implant that can sequentially eradicate bacteria biofilm at the initial period and promote osseointegration at the late period of post‐surgery time is designed. Such surfaces can be excited by near infrared light (NIR), with rare earth nanoparticles to upconvert the NIR light to visible range and adsorb by Au nanoparticles, supported by titanium oxide porous film on titanium implants. Under NIR irradiation, the implant converts the energy of phonon to hot electrons and lattice vibrations, while the former flows directly to the contact substance or partially reacts with the surrounding to generate reactive oxygen species, and the latter leads to the local temperature increase. The biofilm or microbes on the implant surface can be eradicated by NIR treatment in vitro and in vivo. Additionally, the surface exhibits superior biocompatibility for cell survival, adhesion, proliferation, and osteogenic differentiation, which provides the foundation for osseointegration. In vivo implantation experiments demonstrate osseointegration is also promoted. This work thus demonstrates NIR‐generated electrons can sequentially eradicate biofilms and regulate the osteogenic process, providing new solutions to fabricate efficient implant surfaces.
Optical Nonlinearity Enabled Super‐Resolved Multiplexing Microscopy
Authors: Ding Lei , Chen Chaohao , Shan Xuchen , Liu Baolei , Wang Dajing , Du Ziqing , Zhao Guanshu , Su Qian Peter , Yang Yang , Halkon Benjamin , Tran Toan Trong , Liao Jiayan , Aharonovich Igor , Zhang Min , Cheng Faliang , Fu Lan , Xu Xiaoxue , Wang Fan 
Published: November 2023

AbstractOptical multiplexing for nanoscale object recognition is of great significance within the intricate domains of biology, medicine, anti‐counterfeiting, and microscopic imaging. Traditionally, the multiplexing dimensions of nanoscopy are limited to emission intensity, color, lifetime, and polarization. Here, a novel dimension, optical nonlinearity, is proposed for super‐resolved multiplexing microscopy. This optical nonlinearity is attributable to the energy transitions between multiple energy levels of the doped lanthanide ions in upconversion nanoparticles (UCNPs), resulting in unique optical fingerprints for UCNPs with different compositions. A vortex beam is applied to transport the optical nonlinearity onto the imaging point‐spread function (PSF), creating a robust super‐resolved multiplexing imaging strategy for differentiating UCNPs with distinctive optical nonlinearities. The composition information of the nanoparticles can be retrieved with variations of the corresponding PSF in the obtained image. Four channels multiplexing super‐resolved imaging with a single scanning, applying emission color and nonlinearity of two orthogonal imaging dimensions with a spatial resolution higher than 150 nm (1/6.5λ), are demonstrated. This work provides a new and orthogonal dimension – optical nonlinearity – to existing multiplexing dimensions, which shows great potential in bioimaging, anti‐counterfeiting, microarray assays, deep tissue multiplexing detection, and high‐density data storage.
Visible Light‐Driven Eosin Y‐Catalyzed Suzuki‐Type Sulfonylation
Authors: Tang Lin , Lv Ge , Jia Fengjuan , Zhao Rui , Wang Xiaoyu , Zhou Qiuju 
Published: November 2023

AbstractA strategy for sulfonylation of boronic acids with sulfonyl chlorides has been established via Suzuki‐type radical cross‐coupling. This approach allows for the synthesis of more than 50 sulfone examples enabled by photoredox catalysis under visible light radiation. Moreover, the title reaction is applied in late‐stage functionalization of bioactive molecules, and further transformation of the resulting sulfones into 2‐functionalized sulfones, borates, triphenylphosphine oxide and N‐arylcarbazole can be also achieved.
CO2‐Induced Spin‐Lattice Coupling for Strong Magnetoelectric Materials
Authors: Gao Bo , Xu Song , Xu Qun 
Published: November 2023

AbstractThe preparation of 2D magnetoelectric (ME) nanomaterials with strong ME coupling is crucial for the fast reading and writing processes in the next generation of storage devices. Herein, 2D BaTiO3 (BTO)‐CoFe2O4 (CFO) ME nanocomposites are prepared through a substrate‐free coupling strategy using supercritical CO2. Such 2D BTO‐CFO with strong coupling is built through alternating in‐plane and out‐of‐plane epitaxy stacking, leading to remarkable mutual biaxial strain effects for spin‐lattice coupling. As a results, such strain effect significantly enhances the ferroelectricity of BTO and the ferrimagnetism of CFO, where an unexceptionally high ME coupling coefficient of (325.8 mV cm−1 Oe−1) is obtained for the BTO‐CFO nanocomposites.
HSPA8 Activates Wnt/β‐Catenin Signaling to Facilitate BRAF V600E Colorectal Cancer Progression by CMA‐Mediated CAV1 Degradation
Authors: Li Bowen , Ming Hui , Qin Siyuan , Zhou Li , Huang Zhao , Jin Ping , Peng Liyuan , Luo Maochao , Zhang Tingting , Wang Kui , Liu Rui , Liou Yih‐Cherng , Nice Edouard C. , Jiang Jingwen , Huang Canhua 
Published: November 2023

AbstractBRAF V600E attracts wide attention in the treatment of colorectal cancer (CRC) as stratifying and predicting a refractory classification of CRC. Recent evidence indicates that Wnt/β‐catenin signaling is broadly activated and participates in the refractoriness of BRAF V600E CRC, but the underlying molecular mechanism needs to be elucidated. Here, heat shock 70 kDa protein 8 (HSPA8), an essential regulator in chaperone‐mediated autophagy (CMA), is identified as a potential therapeutic target for advanced BRAF V600E CRC. These results show that HSPA8 is transcriptionally upregulated in BRAF V600E CRC, which promotes CMA‐dependent degradation of caveolin‐1 (CAV1) to release β‐catenin into the nucleus and thus activates the Wnt/β‐catenin pathway, contributing to metastasis and progression of BRAF V600E CRC. Of note, HSPA8 directly interacts with the KIFSN motif on CAV1, the interaction can be enhanced by p38 MAPK‐mediated CAV1 S168 phosphorylation. Furthermore, pharmacological targeting HSPA8 by VER155008 exhibits synergistic effects with BRAF inhibitors on CRC mouse models. In summary, these findings discover the important role of the HSPA8/CAV1/β‐catenin axis in the development of refractory BRAF V600E CRC and highlight HSPA8 as a predictive biomarker and therapeutic target in clinical practice.