bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strengthening household resilience for enhanced food security in northwestern Ethiopia: insights from resilience pillars
Authors: Abebe Mekonen Getachew 
Published: February 2025

IntroductionEthiopia has faced significant food insecurity challenges, impacting households from the district to the national level. To strengthen household resilience to food security, it is essential to assess their current resilience levels accurately. The main objective of the study was to assess rural household resilience to food insecurity in Libo Kemkem, a district in northwest Ethiopia, which is particularly susceptible to food insecurity, and identify the contributions of the key pillars that enhance households' capacity to cope with food insecurity.MethodologyThe research used a cross-sectional survey with 216 households, drawn using a multi-stage stratified sampling technique to ensure representation across different subgroups. The Food and Agricultural Organization's Resilience Index Measurement and Analysis II framework was applied to assess the levels of resilience. Factor analysis was used as the main analytical tool to estimate the household resilience index.Result and discussionThe result indicated that asset, adaptive capacity, and access to basic services are highly contributed to resilience with positive scores of scores of 0.85, 0.82, and 0.81 respectively. All the aforementioned scores of resilience pillars are highly significant since it is greater than 0.37 which is recommended for a sample size of 200 and above. Nevertheless, the social safety net is negatively associated with resilience, with a score of 0.68. The average household resilience capacity index was 0.56, showing that 63% of households are less resilient. The overall results of the study showed that households with better assets, adaptive capacity, and better access to basic services, are likely to be more resilient. Consequently, this study recommends applying targeted resilience-oriented strategies programs, packages, and projects that improve these positively contributing pillars of resilience to enhance food security in the area.
Supplementation of DHA enhances the cryopreservation of yak semen via alleviating oxidative stress and inhibiting apoptosis
Authors: Zhu Yanjin , Yu Jun , Li Xupeng , Chen Zhuo , Li Yuan , Xiong Yan , He Honghong , Yin Shi , Lan Daoliang , Li Jian , Yang Lixue , Xiong Xianrong 
Published: February 2025

IntroductionSemen cryopreservation is a crucial method for preserving genetic resources and accelerating the breeding process in domestic animals. However, the frozen-thawed process often leads to physical and chemical damage in semen, resulting in oxidative stress that diminishes sperm vitality and fertilization potential. This study aimed to explore the effects of docosahexaenoic acid (DHA) on the quality of frozen-thawed yak semen.MethodsSemen samples were collected from six healthy adult Maiwa yaks and cryopreserved in liquid nitrogen using extenders with varying DHA concentrations: 0, 0.1, 1, 10, and 100 ng/mL. After thawing, we assessed indices, antioxidant capacity, mitochondrial activity, and apoptosis status to identify the optimal DHA concentration.Results and discussionOur findings indicate that the addition of DHA significantly improved the total motility (TM), progressive motility (PM), velocity of straight line (VSL), curvilinear velocity (VCL), and average path velocity (VAP) of cryopreserved spermatozoa, as well as the integrity of membrane and acrosome (P &lt; 0.05). Additionally, DHA supplementation markedly reduced the levels of reactive oxygen species (ROS) and malondialdehyde (MDA) in frozen-thawed yak spermatozoa (P &lt; 0.05) and enhanced the antioxidant enzyme activities (T-AOC, SOD, CAT, GSH-Px, P &lt; 0.05). It also improved the mitochondrial membrane potential (MMP) and ATP levels (P &lt; 0.05). Notably, the group treated with 10 ng/mL DHA showed significantly better outcomes than the other treatment groups (P &lt; 0.05). Furthermore, the addition of 10 ng/mL DHA to the semen cryopreservation dilution effectively decreased the apoptotic ratio of frozen-thawed yak spermatozoa (P &lt; 0.05), and notably upregulated the expression level of anti-apoptotic protein Bcl-2 (P &lt; 0.05), while downregulating the expression of the pro-apoptotic protein Bax and Caspase3 (P &lt; 0.05).ConclusionIn conclusion, the incorporation of 10 ng/mL DHA into semen extenders enhances the quality and viability of yak sperm after cryopreservation by alleviating the oxidative stress, bolstering antioxidant defenses, and preserving mitochondria function, as well as inhibiting the apoptotic pathway activation.
Modeling and Implementation of Synchronization for Large-Aperture Electromagnetic MEMS Mirrors
Authors: Xu Fahu , Zhao Lingxiao 
Published: February 2025

MEMS-based LiDAR has showcased extensive application potential in the autonomous driving sector, attributed to its cost-effectiveness, compactness, and seamless integration capabilities. However, MEMS LiDAR suffers from a short detection range, due to the small receiving aperture of the MEMS mirror. Our early study attempted to increase the detection range of MEMS LiDAR with a semi-coaxial design. In this paper, we further investigate the synchronization method for large-aperture electromagnetic MEMS mirrors, in which a synchronous motion transfer model of electromagnetic MEMS mirrors is constructed. The results of the simulations and experiments demonstrate that two electromagnetic MEMS mirrors are synchronous with an aperture of 60 π mm2, FoV of 60°, and scanning frequency of 220 Hz. The entire synchronization process of the electromagnetic MEMS mirrors is completed within 10 s, which verifies the feasibility of synchronizing large-aperture electromagnetic MEMS mirrors to increase the detection range of MEMS LiDAR.
The Effects of Combined Scutellaria and Saffron Supplementation on Mood Regulation in Participants with Mild-to-Moderate Depressive Symptoms: A Randomized, Double-Blind, Placebo-Controlled Study
Authors: Dormal Valérie , Suchareau Marlène , Copine Sylvie , Simar Laurent , Deldicque Louise 
Published: February 2025

Background/Objectives: The global prevalence of mental health disorders, particularly anxiety and depression, has increased significantly, with rates further elevated by the COVID-19 pandemic. Conventional pharmacological treatments, while effective, often lead to side effects that can impact patient adherence and quality of life. This has driven interest in safer, natural adjunctive therapies. Crocus sativus L. (Iridaceae) (saffron) and Scutellaria baicalensis Georgi (Lamiaceae) (scutellaria) have individually shown potential, in humans and animals, respectively, as mood regulators, with bioactive compounds that modulate neurotransmitter systems and possess anti-inflammatory and anxiolytic effects. This study aimed (1) to explore the efficacy and safety of scutellaria extracts in humans and (2) to test a possible synergistic effect when combining scutellaria and saffron on mood regulation in individuals experiencing mild-to-moderate depressive symptoms. Methods: In a randomized, double-blind, placebo-controlled trial, 180 participants with mild-to-moderate depressive symptoms were assigned to receive either scutellaria extract alone (SCUTELL’UP®), saffron extract alone (SAFFR’ACTIV®), a combination of scutellaria and saffron extracts (SAFFR’UP®), or a placebo for six weeks. The primary outcome was assessed using a standardized depression scale (Beck Depression Inventory). The secondary outcomes, including anxiety, emotional state, well-being level, and sleep quality, were all assessed using validated questionnaires. Safety and tolerability were evaluated throughout the study period. Results: The results confirmed the beneficial effects of saffron extract on depressive and anxious symptoms, as well as its role in improving sleep quality. For the first time in humans, scutellaria extract demonstrated a positive effect on mood regulation. Furthermore, a synergistic effect of the combination of these two extracts was identified, leading to enhanced improvements in depressive and anxious symptoms and emotional well-being among individuals with mild-to-moderate depression, compared to the placebo group. Minimal adverse effects were reported across all treatment groups. Conclusions: This natural adjunctive nutritional strategy offers a promising alternative for individuals seeking safer options for mental health support. Further research is warranted to exclude potential long-term side effects and to explore potential mechanisms of this combined supplementation.
On the origin of gingival crevicular fluid
Authors: Ippolitov Yu. A. , Seredin P. V. , Goloshchapov D. L. , Ippolitov I. Yu. , Berkovich M. V. , Folomeeva D. M. 
Published: February 2025

Relevance. Limited scientific literature exists on the compositional relationship between dentinal fluid and gingival crevicular fluid, as well as their potential interaction. Objective. This study aims to determine the origin of gingival crevicular fluid, compare its composition with that of dentinal fluid and gingival capillary blood, and assess the potential for their interaction.Materials and methods. This study analyzed three biological fluids: dentinal fluid, gingival crevicular fluid, and gingival capillary blood. A total of 35 volunteers participated in the study. The biological fluids were examined using an infrared microspectrometer at the Australian Synchrotron. Additionally, the microrelief of the enamel in extracted intact teeth, removed for orthodontic reasons, was assessed using a JEOL JSM-6380LV scanning electron microscope (Japan).Results. Dentinal and gingival crevicular fluids exhibit a complex composition comparable to that of blood plasma. The findings reveal spectral modes unique to the infrared (IR) spectra of these fluids. Based on this evidence, it is hypothesized that dentinal fluid may infiltrate the gingival sulcus via dentinal and enamel tubules. During this passage, the fluid interacts with hydroxyapatite crystals, resulting in alkalization. Furthermore, the urea concentration in dentinal fluid is 2.3 times higher than in gingival crevicular fluid, which likely contributes to an increased urea concentration in gingival crevicular fluid diffusing from the gingival papilla.Conclusion. Given the newly discovered potential for dentinal and gingival crevicular fluid mixing, we propose refining the terminology by replacing the term "gingival crevicular fluid" with " dentogingival fluid."
Optimizing Clustering Analysis to Identify High-Potential Markets for Indonesian Tuber Exports
Authors: Prasetya Dwi Arman , Sari Anggraini Puspita , Idhom Mohammad , Lisanthoni Angela 
Published: February 2025

Agriculture is a key contributor to Indonesia's economic growth, with tubers representing the second most important food crop. Despite their significance, the export value of Indonesia’s tuber crops has not yet reached its full potential given the decline in the value of tuber exports since 2021. One of the contributing factors is the restricted range of export market options. This study aims to analyze export trade patterns to identify the most high-potential markets for Indonesian tuber commodities. Clustering analysis is used as a key method to identify market locations by grouping countries based on similar trade characteristics. Clustering was conducted using the Gaussian Mixture Model (GMM), which enhanced by Particle Swarm Optimization (PSO) and evaluated by silhouette score and DBI. The dataset is collected from Indonesia’s Central Bureau of Statistics from 2019 to 2023, focusing on 5 kinds of tuber exports with total of 455 entries and 8 columns. Using the AIC/BIC method, the optimal number of clusters obtained is 2 which are low market opportunities (cluster 0) and high market oppurtunities (cluster 1). Results showed that the GMM model without optimization has silhouette score of 0.7602 and DBI of 0.8398, while the GMM+PSO model achieved an improved silhouette score of 0.8884 and DBI of 0.5584. Both score are categorized as strong structure but, GMM+PSO has higher silhouette score and lower DBI score, demonstrating the effectiveness of PSO in enhancing the clustering model’s performance. The key potential markets for Indonesian tuber exports are primarily concentrated in Asia, including countries such as China, Malaysia, Thailand, Vietnam, Hong Kong, and United States.
Upaya Penurunan Kasus TB Paru di Wilayah Kerja Puskesmas Kresek Kecamatan Kresek, Kabupaten Tangerang, Provinsi Banten
Authors: Aufatunnisa Fatimah , Syahputri Rahmi , Hafidza Azzahra , Sanjaya Juliana 
Published: February 2025

data at the Kresek Community Health Center, the number of tuberculosis cases increased from January to May. Seeing this, it is necessary to carry out a community diagnosis approach to further analyze and identify the factors causing the increase in cases of pulmonary tuberculosis so that immediate intervention can be carried out to prevent the spread and reduce the number of new cases of pulmonary tuberculosis in the working area of the Kresek Community Health Center, Tangerang Regency. Objective: To enhance public awareness of TB, proper coughing, and handwashing within the Kresek Community Health Center’s operational area. Method: Utilizing the Blum Paradigm for community diagnosis to identify underlying causes, conducting mini-seurveys to gather data, the non-scoring Delphi method to prioritize problem, and fishbone diagrams to determine root causes of issues. Interventions include education on TB, cough etique and handwashing steps. Intervention is monitored using the Plan-Do-Check-Action (PDCA) cycle, along with systemic approach to evaluation. Results: Lifestyle factors was contributing to hig TB cases according to the Blum Paradigm. Intervention I (Pulmonary TB) outcomes indicate 29 participants (80,5%) experienced an improvement in post-test score compared to pre-test, wiht 32 participants (88,9%) achieving a post-test score ≥70. Intervention II (PHBS) outcomes indicate 34 participant (94,4%) showed an improvement in post-test score compared to pre-test, and 35 participants (97,2%) achieved a post-test score ≥70 and 6 randomly selected participants executed all two demonstration. Conclusion: There has been an improvement in knowledge regarding pulmonary TB, cough etiquette, and handwashing steps in the working area of Kresek Community Health Center.
Abordagens Cirúrgicas para Tratamento da Insuficiência Cardíaca Avançada: Comparação entre Implante de Coração Artificial e Transplante Cardíaco
Authors: Felipe Laurindo Couto  , Ana Kelly de Azevedo Gonçalves  , Caio Enzo Dantas de Paiva Queiroz  , Monaliza Carvalho Alves Feitosa  , Maria Eduarda Torreão Medeiros Teobaldo  , Bruno Rafael de Souza Honorato  , Brenda Tawares Batista  , Gabriela Júlia Pereira Chacon de Araújo  , Maria Cecília Vieira Stewart Thomaz  , Marialice Pinto Viana Correia  , Mary Morioka  
Published: February 2025

O tratamento da insuficiência cardíaca avançada representa um desafio significativo na cardiologia, exigindo abordagens cirúrgicas de alta complexidade. As principais opções para esse tratamento se destacam o transplante cardíaco e o implante de coração artificial, cada um com indicações, benefícios e desafios específicos. Essa escolha depende de fatores como a disponibilidade de órgãos para transplante, a condição clínica do paciente e a evolução tecnológica dos dispositivos de assistência circulatória. A pesquisa foi realizada no indexador PubMed, utilizando os termos “Insuficiência Cardíaca”, “Transplante Cardíaco”, “Coração Artificial”, “Dispositivos de Assistência Ventricular”, “Cirurgia Cardíaca” e “Complicações Pós-operatórias”, combinados pelo operador booleano AND, no intervalo de 2015 a 2025, nos idiomas inglês e português. Os resultados apontam que, embora o transplante cardíaco ainda seja considerado o padrão-ouro no tratamento da insuficiência cardíaca terminal, a falta de doadores e as complicações associadas à imunossupressão estimulam o avanço dos corações artificiais. Dispositivos de assistência ventricular e corações artificiais têm se mostrado eficazes como terapia de ponte para o transplante ou até mesmo como tratamento definitivo em determinados casos. Além disso, nota-se a importância de estratégias para reduzir complicações pós-operatórias, como infecções, tromboses e falência orgânica, otimizando tanto a sobrevida quanto a qualidade de vida dos pacientes submetidos a essas intervenções.
Utilização de Plasma Rico em Plaquetas e Plasma Rico em Fibrina em Ferida Crônica de Paciente Diabético: relato de caso.
Authors: Oliveira de Araújo Alves Ana Elizabeth , Marques Braga Ana Beatriz , Rodrigues da Silva Fernandes Beatriz , Bispo da Fonseca Margareth , Maraschine Barbosa Marianne , Firmino Lima de Oliveira Marina 
Published: February 2025

Introdução: A importância do plasma sanguíneo, e suas propriedades cicatrizantes em tratamento de feridas crônicas é uma terapia promissora na medicina regenerativa. O plasma rico em plaquetas é extraído do sangue venoso, composto de células responsáveis pela ativação da defesa do organismo. Sua aplicação em feridas crônicas junto com a fibrina rica em plaqueta, promove aceleração do processo de cicatrização e regeneração tecidual. Objetivo: Realizar procedimento de aplicação de plasma rico em plaquetas (PRP) e fibrina rica em plaquetas (PRF) em ferida de um paciente diabético avaliando a eficácia e segurança do tratamento. Métodos: Trata-se de um relato de caso, realizado em uma clínica escola de um centro universitário privado do Distrito Federal. Foram coletados dados clínicos relatado em entrevista com paciente, fotodocumentação em todas as aplicações e o paciente foi orientado sobre assinatura do termo de consentimento livre e esclarecido. Foram realizadas coletas de sangue em cada sessão. Este foi centrifugado a 1800 rpm para obtenção do PRP e PRF para posterior aplicação. O concentrado foi quantificado em relação a sua densidade. Resultados: Ambas as aplicações de PRP e PRF nas feridas resultou em uma melhora importante na cicatrização e regeneração tecidual. Observou-se uma redução no tamanho da ferida crônica e oxigenação tecidual. Conclusão: Com base nos resultados obtidos, pode-se concluir que as aplicações de plasma foram um mecanismo auxiliar eficaz e relevante na recuperação da ferida do paciente, demonstrando potencial para ser um tratamento valioso em casos semelhantes.
O IMPACTO DA MICROBIOTA CUTÂNEA NA RESPOSTA TERAPÊUTICA DA DERMATITE ATÓPICA
Authors: Lênio Airam de Pinho  , Gustavo Cavalcante de Freitas  , Charlene Glaucia Nunes de Almeida  , Marcela Lourenço Lacerda  , Fernanda Oliveira Brito dos Reis  , Lourdes Judith Medeiros Max  , Angélica de Almeida  , Isaque Ramos Silva  , Gabriela Romano de Oliveira  , Rodrigo Daniel Zanoni  
Published: February 2025

Trata-se de uma revisão integrativa da literatura, Foi possível assim estruturar a seguinte pergunta norteadora: “Quais os impactos da microbiota cutânea na resposta terapêutica da dermatite atópica?”. Foi feito um levantamento através da biblioteca eletrônica sendo a Biblioteca Virtual em Saúde (BVS), sendo selecionada as seguintes bases de dados: Literatura Latino-Americana e do Caribe em Ciências da Saúde (LILACS) e Medical Literatures Analysis and Retrieval System Online (MEDLINE), foi utilizado os descritores consultados nos Descritores em Ciência e Saúde (DeCS), no mês de fevereiro de 2025, sendo: “Microbiota”, “Dermatite atópica” e “Terapêutica”, utilizando o operador booleando AND entre os descritores quando combinados. Após a aplicação dos critérios de elegibilidade foram utilizados dez artigos selecionados ao total. De acordo com os estudos encontrados, a microbiota cutânea de pacientes com dermatite atópica (DA) difere significativamente da microbiota de indivíduos saudáveis. Uma das alterações mais frequentemente observadas é a redução da diversidade microbiana, ou seja, o número de diferentes espécies de microrganismos presentes na pele. Essa diminuição na diversidade pode levar a um desequilíbrio na comunidade microbiana, tornando a pele mais vulnerável a infecções e inflamações. Em suma, a microbiota cutânea emerge como um ator crucial no intrincado cenário da dermatite atópica (DA), exercendo influência tanto na patogênese da doença quanto na resposta aos tratamentos. As alterações observadas na microbiota de pacientes com DA, como a redução da diversidade e o aumento da abundância de espécies específicas, como o Staphylococcus aureus, contribuem para a disfunção da barreira cutânea, a inflamação crônica e a exacerbação dos sintomas.
MÉTODOS DE PREVENÇÃO AO TRAUMA DE FACE EM ACIDENTES DE TRÂNSITO COM ÊNFASE PARA FRATURAS NASAIS: UMA REVISÃO DA LITERATURA DE BASE NACIONAL
Authors: Lima Anycia Laura Oliveira da Silva Matos , Santos Ana Clara Ferreira dos , Rodrigues Eduarda Ellen da Silva , Paiva Danielle Cardoso Batista de , Falcão Emily Kerolaynne Gomes , Oliveira Jeanete Marília Santos Lino de , Silva Kisla Monteiro da , Santos Lívia Nayane Simão dos , Silva Myllena Galvão da , Vasconcelos Rafaela Brito 
Published: February 2025

Introdução: O trauma facial decorrente de acidentes de trânsito é uma ocorrência frequente e de grande impacto nos sistemas de saúde, com as fraturas nasais sendo a lesão mais comum. A posição proeminente do nariz e sua estrutura frágil tornam essa região especialmente vulnerável durante colisões. Embora o avanço da tecnologia de segurança veicular tenha reduzido a mortalidade em acidentes, as fraturas nasais ainda permanecem frequentes devido a comportamentos inseguros no trânsito, como a não utilização do cinto de segurança e o excesso de velocidade. Diante disso, é fundamental explorar e enfatizar medidas preventivas que possam minimizar a ocorrência desse tipo de lesão. Objetivos: O presente estudo objetivou revisar a literatura no que se refere as principais medidas preventivas que podem ser adotadas para redução da ocorrência de fraturas nasais em acidentes de trânsito, com foco nos equipamentos de segurança e métodos preventivos relacionados ao veículo.

Métodos: A revisão bibliográfica se deu através da busca nas bases de dados SciELO, Biblioteca Virtual em Saúde (BVS) e em dados Nacionais do Governo. Foram utilizados os descritores em português “Prevenção de Acidentes” “Segurança no Trânsito” “Septo Nasal” e “Cintos de Segurança” e suas correspondentes em inglês, dentro do período dos últimos 18 anos. Resultados: Mediante a revisão bibliográfica, há inúmeros métodos para prevenção das fraturas faciais, dentre os quais, destacam-se os cuidados automotivos, tanto dos motoristas e ciclistas, bem como do estado do automóvel, como a devida revisão no sistema de pneus e freios. Conclusões Finais: A prevenção de fraturas nasais em acidentes de trânsito está diretamente relacionada ao uso de equipamentos de segurança automotiva, como o cinto de segurança, e capacetes, bem como, no uso de medidas preventivas ligadas ao veículo, tais como manutenção dos freios, pneus, uso correto do sistema de suspensão, e ainda, manutenções regulares do veículo. A conscientização da população sobre o uso correto desses dispositivos e a implementação de veículos com tecnologias de proteção avançada são medidas fundamentais para reduzir a incidência de trauma facial. O compromisso com a segurança no trânsito pode salvar vidas e prevenir lesões debilitantes, como as fraturas nasais com sequelas permanentes.