bluuebunny/crossref_metadata_2025_split huggingface dataset:
One Health governance principles for AMR surveillance: a scoping review and conceptual framework
Authors: Ruckert Arne , Harris Fiona , Aenishaenslin Cécile , Aguiar Raphael , Boudreau-LeBlanc Antoine , Pedro Carmo Luís , Labonté Ronald , Lambraki Irene , Parmley E. Jane , Wiktorowicz Mary E. 
Published: February 2024

Abstract
Antimicrobial resistance (AMR) is a pressing global health issue with serious implications for health, food security, and livelihoods. Collective action, from local to global, that draws on the One Health (OH) approach to facilitate collaboration between the human, animal, and environmental sectors is required to inform initiatives to mitigate AMR. For AMR surveillance, this involves applying an intersectoral, multistakeholder perspective to guide the co-creation of knowledge and policy around the collection, analysis, and application of surveillance data to detect, monitor, and prevent AMR health threats. Currently, there is little available evidence on how to operationalize a OH approach to support integrated AMR surveillance systems, or on how the governance of such systems facilitates intersectoral action on AMR. We conducted a scoping review of the literature to identify the governance domains most relevant to applying the OH approach to the design and evaluation of AMR surveillance systems. We found that governance is a crucial component of the development of surveillance systems equipped to tackle complex, structural issues such as AMR. The governance domains identified include participation, coordination and collaboration, management, sustainability, accountability and transparency, and equity. These domains are relevant throughout all stages of policy design, implementation, and evaluation of AMR surveillance systems. Equity is both a domain and an essential component of the other domains. All the domains are interdependent and co-constitutive, so that progress in one domain can accelerate progress in another. The conceptual framework presented in this article can inform the design and evaluation of OH AMR governance systems and other complex health challenges that have similar barriers and facilitators to OH governance. The qualitative evaluation questions developed for each domain facilitate assessment of the breadth (the range of actors involved in governance) and depth (how meaningful their engagement is) for each domain relevant to OH governance. Finally, the prioritization of formal, sustainable, and democratic governance of AMR can help to facilitate achievement of the sustainable development goals (SDGs) and promote conservation of the use of antimicrobials for future generations.
Pattern of anuran infection by acanthocephalans from the Cerrado, Northeastern Brazil with a summary for South America
Authors: dos Santos B.R. , Teixeira A.A.M. , do Nascimento J.M. , Brito S.V. 
Published: February 2024

AbstractIn Brazil, acanthocephalans parasitise anurans in several biomes. In the present study, we performed an analysis of acanthocephalan infections across 175 anuran individuals from the Cerrado biome, belonging to ten species:Boana raniceps, Pithecopus hypochondrialis, Scinax fuscomarginatus, Scinax x-signatus,Leptodactylus pustulatus, Leptodactylus macrosternum, Leptodactylus vastus, Physalaemus cuvieri, Adenomera hylaedactyla, andElachistocleis piauiensis.We also verified the specificity of the parasites using theSTD* index. Additionally, we conducted a survey of acanthocephalan infection in anurans in South America. The studied assemblage in the Brazilian Cerrado presented 57 parasitised hosts of 175 specimens (overall prevalence: 32.6%). In total, 437 acanthocephalans cystacanths were recorded, among which 286 presented the same morphotype but could not be identified, 148 belonged to the genusCentrorhynchus, and three belonged toOncicola. Unidentified acanthocephalans had a higher prevalence inL. vastus(53.85%) and the highest intensity was inL. pustulatus(17±16). The highest prevalence ofCentrorhynchussp. was in the speciesS. fuscomarginatus(28.57%), while the highest intensity was observed inL. vastus(111). The taxonOncicolasp. it had a prevalence of 3.23% and an intensity of 3 only in S.x-signatus. The highest specificity was recorded forOncicolasp. (STD*= 1), whereas the lowest was found inCentrorhynchussp. (STD*= 2.21). Finally, according to the survey for South America, we found ten records of acanthocephalan taxa parasitizing 58 species of anurans distributed in seven countries (Brazil with the most records).
Host-specific Cryptosporidium, Giardia and Enterocytozoon bieneusi in shelter dogs from central Europe
Authors: Szydłowicz Magdalena , Zajączkowska Żaneta , Lewicka Antonina , Łukianowski Błażej , Kamiński Mateusz , Holubová Nikola , Sak Bohumil , Kváč Martin , Kicia Marta 
Published: February 2024

AbstractCryptosporidium spp., Giardia intestinalis and microsporidia are unicellular opportunistic pathogens that can cause gastrointestinal infections in both animals and humans. Since companion animals may serve as a source of infection, the aim of the present screening study was to analyse the prevalence of these intestinal protists in fecal samples collected from dogs living in 10 animal shelters in central Europe (101 dogs from Poland and 86 from the Czech Republic), combined with molecular subtyping of the detected organisms in order to assess their genetic diversity. Genus-specific polymerase chain reactions were performed to detect DNA of the tested species and to conduct molecular subtyping in collected samples, followed by statistical evaluation of the data obtained (using χ2 or Fisher's tests). The observed prevalence was 15.5, 10.2, 1 and 1% for G. intestinalis, Enterocytozoon bieneusi, Cryptosporidium spp. and Encephalitozoon cuniculi, respectively. Molecular evaluation has revealed the predominance of dog-specific genotypes (Cryptosporidium canis XXe1 subtype; G. intestinalis assemblages C and D; E. cuniculi genotype II; E. bieneusi genotypes D and PtEbIX), suggesting that shelter dogs do not pose a high risk of human transmission. Interestingly, the percentage distribution of the detected pathogens differed between both countries and individual shelters, suggesting that the risk of infection may be associated with conditions typical of a given location.
Mādayān ī Wīrāzagān: a newly discovered Middle Persian text: transliteration, transcription, and translation
Authors: Nikoghosyan Ruben 
Published: February 2024

AbstractIn 2017, the editio princeps of a newly discovered Middle Persian text, the “Mādayān ī Wīrāzagān” or simply “Wīrāzagān”, was published by Raham Asha. This text, which is important not only from a literary and religious perspective, but also from a mythological point of view, was previously unknown to the scholarly community. The Middle Persian original of the text is found in the Codex TD 26 (49r-62v), preserved in the library of the K.R. Cama Oriental Institute, Mumbai. The manuscript was first discovered and studied by R. Asha in March 2011. The preliminary remarks on the Mādayān ī Wīrāzagān and other texts contained in the Codex TD 26 (Ms. R 494) were published in 2012 in the journal of the same institution. Here I present a translation (accompanied by the transliteration and transcription) of the original text published on pages 3–16 of Asha's book.
Lazy, Selfish and Ruthless: Marketing Legal Information Services
Authors: Leopold Matthew 
Published: February 2024

Abstract“I will build it and so they will come” is not an effective strategy for any business or business function, Matthew Leopold tells us, and in this article, based on his presentation at the BIALL Conference in Belfast, he expands on this, exploring the importance of marketing legal information services internally and externally. Drawing on marketing principles and insights from renowned marketing thought leaders and academic research, this paper presents a four-step framework to enhance marketing effectiveness: understanding marketing's role, capturing attention through relevance and connection, delivering impactful communications and implementing actionable campaigns. By employing these strategies, legal information professionals can effectively promote their library services, enhance their visibility and meet the evolving needs of their audience.
Increasing Your Visibility and Going Beyond Your Job Title: the Pros and Cons of Saying Yes to Everything
Authors: Hunter Ian 
Published: February 2024

AbstractThis article by Ian Hunter, which has been adapted from his BIALL Conference presentation at the Belfast Europa Hotel, examines increasing the visibility of law firm library and information services in terms of what should be done and what should not be done. Or, as Ian puts it: “Is saying yes to everything really the right thing to do?”
Commercial Awareness in the Law Library: a New Role for Academic Law Librarians?
Authors: Cummings Lauren 
Published: February 2024

AbstractIn this article, which expands on a lightning talk that was delivered at the BIALL Conference 2023, Lauren Cummings discusses how she developed and delivered a commercial awareness workshop to third-year students at Goldsmiths, University of London. She then reflects on how employability training relates to information skills and how developing these skills can help students from less advantaged backgrounds achieve their career goals. Lauren also discusses how employability work might fit into the role of the academic law librarian.
Blazing a Trail with Library Apprenticeships
Authors: Sullivan Emma , Smythe Sandra 
Published: February 2024

AbstractIn this article Emma Sullivan and Sandra Smythe go through the presentation they gave at the BIALL conference entitled “Apprenticeship pathways into the library, information and knowledge profession”. Emma and Sandra co-Chair the CILIP Trailblazer group, which is currently developing a Level 7 Library, Information and Knowledge Professional Apprenticeship Standard. Here they discuss how and why they became involved with the group and why the apprenticeship route is so important for the profession, both for employees and employers. (For more background to the CILIP apprenticeship schemes see page 140 of the Autumn 2023 issue of LIM.)
Rooted in turbulence: arguing ethnicity in folk narratives about violence
Authors: Zhao Yuanhao 
Published: February 2024

Abstract
This article begins with a folk idea, or stereotype, attached to the Hui Muslim minority in China: that of being violent. The analysis focuses on how ideas of ethnicity are contextualized in folk or popular narratives about violence. Specifically, cases presented in this article are narratives where different aspects of violence feature either positively or negatively: as a collective ethnic mark of being unreasonable, as martial spirit, as fighting prowess and so forth. This article argues that differently contextualized ideas of being violent or narratives about violent events enable Hui and non-Hui to not only establish ethnic turfs, but also to co-exist and merge ethnic boundaries, rendering ethnic borders open to redrawing and straddling.
3‐D Ionospheric Imaging Over the South American Region With a New TEC‐Based Ionospheric Data Assimilation System (TIDAS‐SA)
Authors: Aa Ercha , Zhang Shun‐Rong , Erickson Philip J. , Wang Wenbin , Coster Anthea J. , Rideout William 
Published: February 2024

AbstractThis study has developed a new TEC‐based ionospheric data assimilation system for 3‐D regional ionospheric imaging over the South American sector (TIDAS‐SA) (45°S–15°N, 35°–85°W, and 100–800 km). The TIDAS‐SA data assimilation system utilizes a hybrid Ensemble‐Variational approach to incorporate a diverse set of ionospheric data sources, including dense ground‐based Global Navigation Satellite System (GNSS) line‐of‐sight Total Electron Content (TEC) data, radio occultation data from the Constellation Observing System for Meteorology, Ionosphere, and Climate‐2 (COSMIC‐2), and altimeter TEC data from the JASON‐3 satellite. TIDAS‐SA can produce a reanalyzed three‐dimensional (3‐D) electron density spatial variation with a high time cadence, yielding spatial‐temporal resolution of 1° (latitude) × 1° (longitude) × 20 km (altitude) × 5 min. This allows us to reconstruct and study the 3‐D ionospheric morphology with multi‐scale structures. The performance of the data assimilation system is validated against independent ionosonde and in situ measurements through an experiment for a strong geomagnetic storm event on 03–04 November 2021. The results demonstrate that TIDAS‐SA can provide detailed and altitude‐resolved information that accurately characterizes the storm‐time ionospheric disturbances in vertical and horizontal domains over the equatorial and low‐latitude regions of South America.
A UK prospective multicentre decision impact, decision conflict and economic evaluation of the 21-gene assay in women with node+ve, hormone receptor+ve, HER2-ve breast cancer
Authors: Holt Simon , Verrill Mark , Pettit Laura , Rigg Anna , Hickish Tamas , Archer Caroline , Dent Jo , Dillon Marianne , Nathan Mark , Barthelmes Ludger , Rehman Shazza , Sharaiha Yousef , Innis Paige , Sai-Giridhar Priya , Khawaja Saira 
Published: February 2024

Abstract
Background
For a tumour profiling test to be of value, it needs to demonstrate that it is changing clinical decisions, improving clinical confidence, and of economic benefit. This trial evaluated the use of the Oncotype DX Breast Recurrence Score® assay against these criteria in 680 women with hormone receptor-positive (HR+), HER2-negative early breast cancer with 1–3 lymph nodes positive (LN+) in the UK National Health Service (NHS).

Methods
Prior to receipt of the Recurrence Score (RS) result, both the physician and the patient were asked to state their preference for or against chemotherapy and their level of confidence on a scale of 1–5. Following receipt of the RS result, the physician and patient were asked to make a final decision regarding chemotherapy and record their post-test level of confidence.

Results
Receipt of the RS result led to a 51.5% (95% CI, 47.2–55.8%) reduction in chemotherapy, significantly increased the relative and absolute confidence for both physicians and patients and led to an estimated saving to the NHS of £787 per patient.

Conclusion
The use of the Oncotype DX assay fulfils the criteria of changing clinical decisions, improving confidence and saving money.
Patients’ perceptions and practices of informing relatives: a qualitative study within a randomised trial on healthcare-assisted risk disclosure
Authors: Nääs Charlotta , von Salomé Jenny , Rosén Anna 
Published: February 2024

AbstractIn a multicentre randomised controlled trial (DIRECT), we evaluate whether an intervention of providing direct letters from healthcare professionals to at-risk relatives (ARRs) affects the proportion of ARRs contacting a cancer genetics clinic, compared with patient-mediated disclosure alone (control). With the aim to explore how the patients included in the trial perceived and performed risk communication with their ARRs we analysed 17 semi-structured interviews with reflexive thematic analysis. All patients described that they disclosed risk information to all close relatives themselves. No integrity-related issues were reported by patients offered the intervention, and all of them accepted direct letters to all their ARRs. Patients’ approaches to informing distant relatives were unpredictable and varied from contacting all distant ARRs, sharing the burden with the family, utilising the offer of sending direct letters, vaguely relying on others to inform, or postponing disclosure. Most patients limited their responsibility to the disclosure, although others wanted relatives to get genetic counselling or felt a need to provide additional information to the ARRs before ending their mission. We also identified confusion about the implication of test results, who needed risk information, and who was responsible for informing ARRs. These misunderstandings possibly also affected risk disclosure. This study revealed that despite accepting the direct letters to be sent to all relatives, the patients also contributed to risk disclosure in other ways. It was only in some situations to distant relatives that the healthcare-assisted letter was the only means of communication to the ARRs.
Renal denervation improves cardiac function independently of afterload and restores myocardial norepinephrine levels in a rodent heart failure model
Authors: Miklovič Matúš , Gawryś Olga , Honetschlägerová Zuzana , Kala Petr , Husková Zuzana , Kikerlová Soňa , Vaňourková Zdeňka , Jíchová Šárka , Kvasilová Alena , Kitamoto Misuzu , Maxová Hana , Puertas-Frias Guillermo , Mráček Tomáš , Sedmera David , Melenovský Vojtěch 
Published: February 2024

AbstractRenal nerves play a critical role in cardiorenal interactions. Renal denervation (RDN) improved survival in some experimental heart failure (HF) models. It is not known whether these favorable effects are indirect, explainable by a decrease in vascular afterload, or diminished neurohumoral response in the kidneys, or whether RDN procedure per se has direct myocardial effects in the failing heart. To elucidate mechanisms how RDN affects failing heart, we studied load-independent indexes of ventricular function, gene markers of myocardial remodeling, and cardiac sympathetic signaling in HF, induced by chronic volume overload (aorto-caval fistula, ACF) of Ren2 transgenic rats. Volume overload by ACF led to left ventricular (LV) hypertrophy and dysfunction, myocardial remodeling (upregulated Nppa, MYH 7/6 genes), increased renal and circulating norepinephrine (NE), reduced myocardial NE content, increased monoaminoxidase A (MAO-A), ROS production and decreased tyrosine hydroxylase (+) nerve staining. RDN in HF animals decreased congestion in the lungs and the liver, improved load-independent cardiac function (Ees, PRSW, Ees/Ea ratio), without affecting arterial elastance or LV pressure, reduced adverse myocardial remodeling (Myh 7/6, collagen I/III ratio), decreased myocardial MAO-A and inhibited renal neprilysin activity. RDN increased myocardial expression of acetylcholinesterase (Ache) and muscarinic receptors (Chrm2), decreased circulating and renal NE, but increased myocardial NE content, restoring so autonomic control of the heart. These changes likely explain improvements in survival after RDN in this model. The results suggest that RDN has remote, load-independent and favorable intrinsic myocardial effects in the failing heart. RDN therefore could be a useful therapeutic strategy in HF.
Effect of bulbospongiosus muscle injection with botulinum-A toxin for treatment of lifelong premature ejaculation; a randomized controlled trial
Authors: Almekaty Khaled , Ghaith Ahmed , Ragab Maged , Rashed Ayman , Hagras Ayman , Ghoneem Ayman , Raheem Amr Abdel , Zahran Mohamed H. 
Published: February 2024

AbstractThis study aimed at assessing a new line of treatment for lifelong premature ejaculation which is botulinum-A toxin injection into the bulbospongiosus muscle. Sixty patients with lifelong premature ejaculation were independently randomized into 2 groups; group I, 100 U botulinum-A toxin at 10 U/ml saline was injected with ultrasound guidance into the bulbospongiosus muscle and group II which was injected with similar volume of saline. The primary outcome was to compare both groups for changes in the Premature Ejaculation Profile (PEP), Intravaginal Ejaculatory Latency Time (IELT) and partner’s satisfaction at 1, 3 and 6 months after intervention. The second outcome was to compare the adverse events in both groups. Fifty-seven patients completed the study. In group I, the mean PEP increased significantly at 1- (P = 0.02) and 3- months (P = 0.04) with insignificant increase at 6-month (P = 0.6) of follow-up. Also, no significant changes had been noted in IELT or partner’s satisfaction scores throughout the study duration (P > 0.05). In group II, no significant changes had been noted in the PEP, IELT and partner’s satisfaction scores throughout the study duration (P > 0.05). There were insignificant differences in the changes in the mean PEP (P = 0.7, 0.6 and 0.4), IELT (P = 0.6,0.6 and 0.5) and partner’s satisfaction scores (P = 0.5,0.7 and 0.3) in comparison to the baseline values at 1-, 3- and 6- months, respectively between both groups. Adverse events were observed in only 3 patients (5.3%). In group I, mild erectile dysfunction and post micturition dribbling were reported in one patient each. Where in group II, one patient reported bleeding per urethra (P = 0.5). To conclude, injection of botulinum-A toxin into bulbospongiosus seems to be safe but failed to prove clinical efficacy for treatment of lifelong premature ejaculation when compared to placebo.
Ultrafast electronic relaxation pathways of the molecular photoswitch quadricyclane
Authors: Borne Kurtis D. , Cooper Joseph C. , Ashfold Michael N. R. , Bachmann Julien , Bhattacharyya Surjendu , Boll Rebecca , Bonanomi Matteo , Bosch Michael , Callegari Carlo , Centurion Martin , Coreno Marcello , Curchod Basile F. E. , Danailov Miltcho B. , Demidovich Alexander , Di Fraia Michele , Erk Benjamin , Faccialà Davide , Feifel Raimund , Forbes Ruaridh J. G. , Hansen Christopher S. , Holland David M. P. , Ingle Rebecca A. , Lindh Roland , Ma Lingyu , McGhee Henry G. , Muvva Sri Bhavya , Nunes Joao Pedro Figueira , Odate Asami , Pathak Shashank , Plekan Oksana , Prince Kevin C. , Rebernik Primoz , Rouzée Arnaud , Rudenko Artem , Simoncig Alberto , Squibb Richard J. , Venkatachalam Anbu Selvam , Vozzi Caterina , Weber Peter M. , Kirrander Adam , Rolles Daniel 
Published: February 2024

AbstractThe light-induced ultrafast switching between molecular isomers norbornadiene and quadricyclane can reversibly store and release a substantial amount of chemical energy. Prior work observed signatures of ultrafast molecular dynamics in both isomers upon ultraviolet excitation but could not follow the electronic relaxation all the way back to the ground state experimentally. Here we study the electronic relaxation of quadricyclane after exciting in the ultraviolet (201 nanometres) using time-resolved gas-phase extreme ultraviolet photoelectron spectroscopy combined with non-adiabatic molecular dynamics simulations. We identify two competing pathways by which electronically excited quadricyclane molecules relax to the electronic ground state. The fast pathway (<100 femtoseconds) is distinguished by effective coupling to valence electronic states, while the slow pathway involves initial motions across Rydberg states and takes several hundred femtoseconds. Both pathways facilitate interconversion between the two isomers, albeit on different timescales, and we predict that the branching ratio of norbornadiene/quadricyclane products immediately after returning to the electronic ground state is approximately 3:2.