bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASPECTOS CLÍNICOS E TERAPEUTICOS DA ESCLEROSE LATERAL AMIOTRÓFICA
Authors: Cott Mário Cezar Aspett , Teixeira Jr. George Fernandes , Mayer Douglas de Souza Braz , Santos Alcione de Oliveira dos 
Published: November 2023

INTRODUÇÃO: A Esclerose Lateral Amiotrófica é uma doença hereditária que pode levar o paciente a óbito em poucos anos, essa doença degenera o sistema nervoso do indivíduo, afetando suas funções motoras e cognitivas. A Esclerose Lateral Amiotrófica pode ser herdada, afetando o gene que codifica a enzima de cobre-zinco superóxido dismutase. Outro causador da doença de ELA é a alteração do status de cobre com o estresse oxidativo, afetando diretamente o perfil lipídico e o cobre, que possui um papel fundamental no sistema nervoso, pois influencia no estado de oxidação e redução celular. OBJETIVO: Levantar informações acerca da etiologia, do tratamento e os impactos da doença no indivíduo. METODOLOGIA: Por meio de leituras e pesquisas seletivas de artigos e estudos presentes em sites como Scientific Electronic Library Online (SciELO), Public Medical Literature Analysis and Retrieval System (PubMed), Drug Bank e Sci-Hub que retratassem os aspectos clínicos, terapêuticos e etiológicos da Esclerose Lateral Amiotrófica. RESULTADOS: A Esclerose Lateral Amiotrófica é uma doença neurodegenerativa que apresenta origens multifatoriais, como a genética e o estilo de vida do paciente. A doença de ELA acarreta diversos sintomas para os portadores dessa doença, como perca de força, dificuldades para andar, demência, excesso de saliva e tosse em excesso, com isso, o paciente necessita de cuidados especiais e tratamentos específicos. Entre os tratamentos estudados, o método que apresentou mais eficiência foi a terapia neurofuncional, essa terapia busca melhorar a qualidade de vida do paciente, com esse tratamento, a doença não vai ser tratada, mas sim amenizada, diminuindo o progresso da doença e mantendo a independência do paciente. CONCLUSÃO: Com as alterações do perfil lipídico e no status de cobre, a bainha de mielina é danificada, interferindo na contração do músculo, com os diferentes estágios da doença. Com todos os possíveis tratamentos disponíveis para a doença de ELA, o que apresenta maior eficiência é a fisioterapia neurofuncional. A fisioterapia não vai curar ou tratar a doença, e sim diminuir seus danos, a fisioterapia, se acompanhada de uma dieta balanceada, pode manter a independência motora do paciente e retardar os danos da doença de ELA as atividades motoras, melhorando a qualidade de vida.
TRATAMENTO DA SÍNDROME ANTIFOSFOLÍPIDE NA GESTAÇÃO
Authors: Siqueira João Marcos Costa de , Sousa Ana Carolina Rodrigues de , Santos Alcione de Oliveira dos 
Published: November 2023

INTRODUÇÃO: A síndrome antifosfolípide (SAF) é definida pela presença de anticorpos antifosfolípides associados com algum quadro clínico quer sejam: perda gestacional de repetição, trombocitopenia ou trombose arterial ou venosa. Em pacientes portadoras dessa síndrome, a chance de sucesso da gravidez é de apenas 20%, na ausência de uma terapêutica adequada. Ademais, não são raras complicações que levem a prematuridade do feto, podendo alcançar uma margem de 60%. Tal cenário implica, portanto, no consolidado conhecimento dos tratamentos viáveis para contornar essa síndrome. OBJETIVO: Evidenciar a melhor medida terapêutica adotada atualmente para as gestantes portadoras da Síndrome Antifosfolípide. METODOLOGIA: Realizou-se uma pesquisa bibliográfica nas principais plataformas digitais, como Google Acadêmico, Scielo e Biblioteca Virtual em Saúde, buscando-se por artigos completos, gratuitos, escritos entre 2010 e 2022 e publicados nas línguas portuguesas e inglesas. Foram encontrados doze artigos, dos quais foram descartados quatro por não preencherem os objetivos da presente pesquisa. RESULTADOS: Evidenciou-se que a terapêutica padrão ouro para gestações onde a mãe é portadora de SAF se faz com o uso de heparina de baixo peso molecular (HBPM), principalmente a enoxaparina, associada com aspirina (AAS), ambas em baixas dosagens. A HBPM se mostrou mais eficaz que a heparina não fracionada. Sua atuação se dá por meio da inibição da ligação aos fosfolípides, o que ocasiona uma interação entre a heparina e os anticorpos antifosfolípides inibindo a ação destes. Também apresenta a vantagem de não atravessar a barreira placentária, não gerando qualquer efeito adverso ao feto. Já a aspirina atua promovendo a inibição seletiva da síntese de tromboxano A2, prevenindo a trombose de pequenas veias. As dosagens observadas ideais para o tratamento giraram em torno de 40mg e 80mg, respectivamente, por dia. Os usos das medicações devem perdurar durante toda a gestação, sendo suspensa ao se iniciar o trabalho de parto ou 12 horas antes da interrupção da gestação, quando for possível programá-la. Com a adoção de tal estratégia garante-se o sucesso gestacional de até 80% das gravidezes. CONCLUSÃO: A síndrome do anticorpo antifosfolipíde deve ser sempre investigada pelos obstetras e ginecologistas frente aos quadros clínicos de aborto recorrente, óbito fetal, crescimento intrauterino retardado, pré-eclâmpsia grave ou de início precoce, trombocitopenia e em qualquer fenômeno trombótico presente ou como antecedente clínico na vida da mulher, instituindo-se a terapêutica citada o mais rápido possível, visando impedir abortamentos, prematuridades e danos físicos e psicológicos à gestante.
New Minerals from the Redmond Mine, North Carolina, USA: IV. Haywoodite and Hanahanite, Two New Minerals Containing Gordaite-Like Sheets
Authors: Kampf Anthony R. , Smith Jason B. , Hughes John M. , Ma Chi , Emproto Christopher 
Published: November 2023

Abstract
The new minerals haywoodite, [Pb(H2O)10)][Zn12(OH)20(H2O)(SO4)3] (IMA2021-115), and hanahanite, [Zn8(OH)14(SO4)]·3H2O (IMA2022-012), were found in the Redmond mine, Haywood County, North Carolina, USA, where they occur in a highly unusual secondary assemblage that comprises a variety of rare Pb-Zn-Cu sulfates, thiosulfates, and carbonates. Haywoodite has the following properties: colorless to pale pink pseudohexagonal tablets and barrel-like prisms up to about 0.5 mm in diameter; white streak; vitreous luster; brittle; Mohs hardness 2½; curved and stepped fracture; one perfect cleavage on {011}; 3.27(2) g/cm3 measured density; biaxial (−) with 1.588(2), β = 1.600(2), γ = 1.607(2), and 2V (meas.) = 76(2)°. Hanahanite has the following properties: light blue prisms up to 0.3 mm in length; white streak; vitreous luster; brittle; Mohs hardness 3; curved fracture; one very good cleavage on {001}; 3.28(2) g/cm3 measured density; uniaxial (−) with ω = 1.636(3) and ε = 1.620(3). Electron probe microanalyses provided the empirical formulae Pb1.36Zn11.97S3.00O43H41.33 and (Zn6.69Cu1.27Co0.01)Σ7.97S1.00O21H20.04 for haywoodite and hanahanite, respectively. Haywoodite is triclinic, P1¯, a = 8.35298(19), b = 13.2769(7), c = 18.2744(13) Å, α = 92.427(8), β = 90.419(6), γ = 108.214(4)°, V = 1922.94(18) Å3, and Z = 2. Hanahanite is hexagonal, P63, a = 8.312(2), c = 15.295(2) Å, V = 915.2(5) Å3, and Z = 2. The structures of haywoodite (R1 = 0.037 for 6876 I &gt; 2σI) and hanahanite (R1 = 0.065 for 772 I &gt; 2σI) both contain gordaite-like sheets. In the haywoodite structure, a disordered interlayer region contains approximately one Pb and ten H2O pfu. In the hanahanite structure, ZnO4 tetrahedra in adjacent sheets are linked by sharing corners and the interlayer region only contains an H2O group.
Visual perceptual learning is effective in the illusory far but not in the near space
Authors: Zafarana Antonio , Farnè Alessandro , Tamè Luigi 
Published: November 2023

AbstractVisual shape discrimination is faster for objects close to the body, in the peripersonal space (PPS), compared with objects far from the body. Visual processing enhancement in PPS occurs also when perceived depth is based on 2D pictorial cues. This advantage has been observed from relatively low-level (detection, size, orientation) to high-level visual features (face processing). While multisensory association also displays proximal advantages, whether PPS influences visual perceptual learning remains unclear. Here, we investigated whether perceptual learning effects vary according to the distance of visual stimuli (near or far) from the observer, illusorily induced by leveraging the Ponzo illusion. Participants performed a visual search task in which they reported whether a specific target object orientation (e.g., triangle pointing downward) was present among distractors. Performance was assessed before and after practicing the visual search task (30 minutes/day for 5 days) at either the close (near group) or far (far group) distance. Results showed that participants that performed the training in the near space did not improve. By contrast, participants that performed the training in the far space showed an improvement in the visual search task in both the far and near spaces. We suggest that such improvement following the far training is due to a greater deployment of attention in the far space, which could make the learning more effective and generalize across spaces.
What you don’t know can’t hurt you: Retro-cues benefit working memory regardless of prior knowledge in long-term memory
Authors: Loaiza Vanessa M. , Cheung Hiu Wah , Goldenhaus-Manning David T. 
Published: November 2023

AbstractKnowledge stored in long-term memory (LTM) impacts working memory (WM) overall, but it is unclear whether LTM facilitates focusing or switching attention in WM. We addressed this question using the retro-cue paradigm: Briefly presented arrays of individually calibrated numbers of shapes (concrete or abstract) were followed by a blank retention interval (no-cue) or a retro-cue to focus participants’ attention to the to-be-probed shape. Experiment 3 included double retro-cue trials that required participants to switch their attention to a different shape. Participants recalled the color (Experiments 1) or location (Experiment 2) of the probed shape, or recognized the target shape among two other options (Experiment 3). Confirming the overall LTM effect on WM, fewer abstract shapes were needed to match the performance of concrete shapes during the calibration phase. Most importantly, retro-cues benefitted performance regardless of the nature of the shape, suggesting that LTM impacts WM overall without moderating attention.
Astrophysical Distance Scale. VII. A Self-consistent, Multiwavelength Calibration of the Slopes and Relative Zero Points for the Run of Luminosity with the Color of Stars Defining the Tip of the Red Giant Branch
Authors: Madore Barry F. , Freedman Wendy L. , Owens Kayla 
Published: November 2023

Abstract
Given the recent successful launch of the James Webb Space Telescope, determining robust calibrations of the slopes and absolute magnitudes of the near- to mid-infrared tip of the red-giant branch (TRGB) will be essential to measuring precise extragalactic distances via this method. Using ground-based data of the Large Magellanic Cloud from the Magellanic Clouds Photometric Survey along with near-infrared (NIR) data from 2MASS and mid-infrared (MIR) data collected as a part of the SAGE survey using the Spitzer Space Telescope, we present slopes and zero-points for the TRGB in the optical (VI), NIR (JHK), and MIR ([3.6] and [4.5]) bandpasses. These calibrations utilize stars +0.3 ± 0.1 mag below the tip, providing a substantial statistical improvement over previous calibrations which only used the sample of stars narrowly encompassing the tip.
Heavy-ion Acceleration in 3He-rich Solar Energetic Particle Events: New Insights from Solar Orbiter
Authors: Mason G. M. , Roth I. , Nitta N. V. , Bučík R. , Lario D. , Ho G. C. , Allen R. C. , Kouloumvakos A. , Wimmer-Schweingruber R. F. , Rodriguez-Pacheco J. 
Published: November 2023

Abstract
We present Solar Orbiter energetic particle observations of two 3He-rich events with features more clearly observed than in prior studies. The event of 2022 November 9 observed from 0.59 au contained hundreds of ultraheavy (UH; mass >78 amu) ions whereas previous observations at 1 au have shown only an occasional count or two. The event of 2023 April 8 observed from 0.29 au fortuitously had very low ambient activity, making it possible to observe spectra from the 3He acceleration mechanism without contamination, revealing extremely low H and 4He intensities arriving simultaneously with other ions observed in typical 3He-rich events. Taken together with previous studies, we believe these data show that 3He-rich events have a single acceleration mechanism that is responsible for the unique abundance features of 3He, heavy ions, and UH ions. Considering the acceleration model of Roth & Temerin that heats the ions over a broad range of gyrofrequencies away from those damped by H and 4He, we calculate reasonable fits to the observed abundances O–Fe. A key result is that high values of, e.g., Fe/O typical of such events is not due to preferential Fe heating, but on the contrary is due mainly to the depletion of O, which at elevated temperatures has a charge-to-mass ratio in the region of the waves damped by 4He. The model also naturally incorporates features of high-ionization states and neutron-rich isotope enhancements that have been long-standing puzzles in observations of this type of flare.
Hycean Exoplanets as Targets for Technosignature Detection: A Case Study of K2-18 b in the 3–10 GHz Band
Authors: Saide Ramiro C. , Farah Wael , Sheikh Sofia Z. , Pollak Alexander W. , Siemion Andrew P. V. , Cruz Luigi F. , Davis Roy H. , DeBoer David R. , Gajjar Vishal , Karn Phil , Masters Mark , Shumaker Carol , Singh Gurmehar , Snodgrass Michael 
Published: November 2023

Abstract
Recently the James Webb Space Telescope performed near-infrared spectroscopic observations of the atmosphere of a potential Hycean exoplanet, K2-18 b. These spectra provided evidence of methane and carbon dioxide in its atmosphere, along with a possible line attributed to biomarker dimethyl sulfide. In this work, we present triggered narrow-band radio observations of K2-18 b conducted using the Allen Telescope Array over 3–10 GHz, in search of signs of artificially produced radio emissions (technosignatures). We do not find any spatially isolated signals in the direction of K2-18 b, establishing lower and upper limits on the equivalent isotropic radiated power (∼1013–1016 W) of potential extraterrestrial transmitters between 3 and 10 GHz. This study emphasizes the importance of ongoing observations to further explore K2-18 b’s potential as a candidate for the detection of technosignatures.
Aménités territoriales et dérèglement climatique : quelles conséquences pour les modèles de développement résidentiels des communes littorales de la région Provence-Alpes Côte d’Azur ?
Authors: Monier Vincent , Ben Saad Myriam , Sabrinni-Chatelard Fernanda 
Published: November 2023

Les différents changements climatiques en cours et à venir impactent de manière conséquente la région Provence-Alpes Côte d’Azur (PACA). Au travers d’une approche pluridisciplinaire et exploratoire, cet article vise à tracer une typologie des développements résidentiels des communes littorales. À partir des statistiques (Corine Land Cover, 2018) et de la cartographie présentée dans cet article, les résultats décrivent une région PACA caractérisée par un défi d’adaptation faible et un défi d’atténuation élevé. À cet effet, au regard de nouvelles contraintes imposées par la loi climat et résilience, une efficacité sur ce degré de gravité du dérèglement climatique peut être envisagée. Cet instrument juridique ne devrait pas agir seul mais en se combinant à d’autres mécanismes financiers. Classification JEL : K32, Q51, Q54, R14
L’extrême droite estonienne et la Suède
Authors: Kesa Katerina 
Published: November 2023

Afin de comprendre la circulation d’informations et d’images entre les pays de l’espace baltique, cet article cherche à montrer comment les informations et images (souvent négatives ou jugées telles), venant de la Suède à propos des migrants ou concernant la situation des minorités sexuelles sont utilisées par les acteurs d’extrême droite estonienne, EKRE, pour promouvoir leur idéologie xénophobe et ultra-conservatrice en Estonie. En s’intéressant au discours de ce parti estonien et au contenu de son média « hyperpartisan » en ligne, Uued Uudised, en référence à la Suède, nous comprenons comment la présentation de ce pays nordique comme « contre-modèle » permet à EKRE de fonder ses actions politiques. Cette contribution s’intéresse aussi plus largement à la transnationalisation de l’activité d’EKRE, en observant aussi bien la coopération de cette formation avec d’autres mouvements de l’espace nordique que la reprise des pratiques et stratégies en matière de politique étrangère.
Les traces inconscientes des traumatismes vécus par les générations précédentes sont-elles des traces mnésiques phylogénétiques ?
Authors: Diatkine Gilbert 
Published: November 2023

Comment les traces des évènements vécus par les générations précédentes s’inscrivent-elles dans notre inconscient ? Dans Totem et tabou, Freud soutient qu’elles se transmettent de génération en génération. Dans Moïse et le monothéisme, il propose au contraire que leurs traces mnésiques phylogénétiques y sont inscrites depuis les origines. Mais une trace ne peut être « mnésique », c’est-à-dire remémorable, que si elle est liée à des représentations de mots. Personne n’a donc de souvenirs antérieurs à sa propre acquisition du langage et encore moins des évènements antérieurs à sa naissance. Freud serait néanmoins revenu à l’idée de trace mnésique phylogénétique pour réaffirmer sa confiance dans le processus de civilisation, sérieusement ébranlée par sa rencontre directe avec les nazis au moment de l’Anschluss.
Common methods and outcomes of employee engagement: a systematic literature review towards identifying gaps in research
Authors: Priyashantha Gayan , De Alwis A.Chamaru , Welmilla I. 
Published: November 2023

As global surveys reported, employee engagement is currently in crisis. Hence, this study aimed to discover (1) common methods and outcomes of employee engagement and (2) researchgaps relating to employee engagement. The study employed the Systematic Literature Review (SLR) methodology. Publications selected for this review were based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, as it is recommended for SLRs. The review included two 260 studies published in Scopus from 2008 to 2021. The studies were analysed through bibliometric analysis for reviewing purposes and achieving the two objectives. Findings indicate different methods and outcomes of employee engagement.
Three-dimensional evaluation of maxillary sinus volume, skeletal and dentoalveolar maxillary anterior region, in unilateral palatally impacted maxillary canine (Cross-sectional study)
Authors: Faiq Sahar Y. , Dewachi Zaid 
Published: November 2023

OBJECTIVES:
Three-dimensional evaluation of maxillary sinus volume using VR mesh and correlate it with the volume of maxillary canine, lateral incisor, and dentoalveolar and skeletal dimensions in both impacted and non-impacted sites.

MATERIALS AND METHODS:
In a retrospective cross-sectional study, cone beam computed tomography scans of 100 patients with unilateral palatally impacted maxillary canine were analyzed. Canine, lateral incisor, and maxillary sinus volumes on the impaction and non-impaction sides were measured using DICOM files, with three-dimensional softwares (MIMICS) and VR mesh to accomplish this assessment.

RESULTS:
There were no significant differences in canine and lateral incisors volumes between male and female patients in the impacted side at (p > 0.05) while the maxillary sinuses volume revealed a statistical difference (P = 0.022) between male (12642 ± 810) and female (12481 ± 650) patients in the impacted side. A strong positive correlation was found between canine and lateral incisor volume for male patients in the non-impacted (r = 0.420**, P = 0.008) and impacted sides (r = 0.334*, P = 0.038).

CONCLUSIONS:
There were no significant differences in the canine volume, the height of the anterior alveolar ridge (AARHMLI), and anterior dentoalveolar (ADAHMLI) of maxillary lateral incisors in the impacted/non-impacted side, but it showed a statistically significant difference for the lateral incisors volume in the impacted and non-impacted sides for male and female patients. The maxillary sinus volumes revealed a statistical difference between males and females in impacted and non-impacted sides.
Stress effect on the mandibular dental arch by mentalis muscle over activity, finite element analysis
Authors: Al Zubaidi Saba H. , Alsultan Mustafa M.H. , Hasan Lamiaa A. 
Published: November 2023

OBJECTIVES:
The perioral muscles postural and functional abnormality should be clearly evaluated. The influence of the abnormal function of mentalis muscle on the shape and posture of the mandible was evaluated using a finite element approach.

METHODS:
Finite element analysis was used to create a three-dimensional representation of a human mandible that represents a dry normal mandible with teeth (33-36 gm/cm2). Pressures were applied directly to the labial surface of the mandible's lower anterior dento-alveolar structure reflecting the normal lips muscle function. While on abnormal swallowing pattern, lip muscle force (300 gm\cm2) had been assumed.

RESULTS:
Shape and postural abnormality of the mandible with malocclusion particularly at the anterior dentoalveolar and basal bone region in sagittal direction as well as inward pressure on the mandibular posterior region.

CONCLUSION:
Abnormal perioral muscle function throughout growth and development may result in a shape and postural abnormality of the mandible and a companying malocclusion.
Dental arch form in a sample of Iraqi adults with sickle cell anemia using 3D scanning technique: A cross-sectional study
Authors: Abdullah Hawraa Ali , Ahmad Haider M. A. 
Published: November 2023

OBJECTIVE:
Sickle cell anemia (SCA) is a hematological condition that involves the synthesis of sickle-shaped, hemoglobin with a short lifespan. This study employed three-dimensional (3D) scanning to pinpoint the most common arch form in a sample of Iraqi adults with SCA.

MATERIALS AND METHODS:
A cross-sectional study included maxillary and mandibular casts of 50 patients (25 male and 25 female) with SCA and 50 participants in a control group (25 male and 25 female). The facio-axial (FA) point was digitized on each tooth's labial or buccal surface using SolidWorks® 2020 software. The dimensions of the arch were calculated using two proportional measures and four linear measurements. The dental arch form was determined using 3M templates, and the arches were categorized as square, ovoid, or tapered to establish the most-common arch form. Chi-square was used to compare arch form distribution, and an independent t-test was used to calculate the difference between the control group and the SCA group.

RESULTS:
The tapered arch was the predominant form in SCA males and females for the maxilla and the mandible. The molar vertical distance (upper and lower) was significantly higher in males in the SCA group than in males in the control group. There was no significant difference between females in the SCA group and females in the control group.

CONCLUSION:
Most patients with SCA had tapered arches. Sagittal jaw dimensions in males with SCA were more affected by marrow hyperplasia. There was little if any to no effect on females with SCA.