bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrative taxonomy of Serrasentis gibsoni n. sp. (Acanthocephala: Isthmosacanthidae) from flatfishes in the Gulf of Mexico
Authors: Martínez-Aquino A. , García-Teh J.G. , Ceccarelli F.S. , Aguirre-Macedo M.L. , Vidal-Martínez V.M. 
Published: December 2023

Abstract
The Isthmosacanthidae acanthocephalan species of the genus Serrasentis are parasites of marine teleosts and an elasmobranch. In this study, Serrasentis gibsoni n. sp. is described from the intestines of four flatfish species (Paralichthyidae), namely Ancyclopsetta quadrocellata, Cyclopsetta chittendeni, Syacium gunteri, and S. papillosum from 10 oceanic sites in the Gulf of Mexico (GoM). Twenty sequences of the ‘barcoding’ region of cytochrome C oxidase subunit I gene were obtained from 20 adults of Serrasentis gibsoni n. sp. Additionally, five sequences of the barcoding region were obtained from five adults of rhadinorhynchid Gorgorhynchus lepidus from C. chittendeni, S. papillosum and one species of Haemulidae, Haemulom aurolineatum, from five oceanic sites from the GoM. Two phylogenetic approaches were followed: Bayesian inference and maximum likelihood. In both phylogenetic reconstructions, the sequences of Serrasentis gibsoni n. sp. were recovered as a monophyletic group within the genus Serrasentis and placed as a sister group to G. lepidus. However, due to the lack of molecular data for species of the Isthmosacanthidae and Rhadinorhynchidea, these phylogenetic inferences must be taken with caution. Serrasentis gibsoni n. sp. is the first species of Serrasentis described from Paralichthyidae flatfish species from marine waters of the Americas and from the GoM. Based on the barcoding data set analyzed, Serrasentis gibsoni n. sp. appears to have high intraspecific genetic variation; thus, it is necessary to continue exploring the genetic diversity of this species to infer its intraspecific evolutionary patterns.
Las Huelgas: Arabic inscriptions for Christian liturgy
Authors: Francis Razan 
Published: December 2023

AbstractThis article analyses the little-studied thirteenth-century Arabic inscriptions of the monastery of Santa María la Real de Las Huelgas in Burgos, Spain. Despite their creation during an intensifying Christian–Muslim conflict, they were part of a decorative programme that relied on shared religious ideas and iconography. Their incorporation reinforced daily, funerary and commemorative monastic liturgies. While the article explores the Islamic provenance of these inscriptions, it also reveals the overlooked Arabic New Testament as a source. The inscriptions’ provenance, however, was deliberately obscured first and foremost by the nature of their visual display. Examining the relationship of the Latin to the Arabic inscriptions illustrates an unusual symbiosis between the meaning of the inscriptions, the iconography and the monastery's ritual. This symbiosis was formulated through a highly selective editorial process on the part of the Christian patrons, and predicated on their knowledge of the finer points of Islamic doctrine and cultural practices.
Store-specific grocery shopping patterns and their association with objective and perceived retail food environments
Authors: Recchia Daisy , Perignon Marlène , Rollet Pascaline , Bricas Nicolas , Vonthron Simon , Perrin Coline , Sirieix Lucie , Charreire Hélène , Méjean Caroline ,   Surfood-Foodscapes Working Group
Published: December 2023

Abstract

Objective:
To explore store-specific grocery shopping patterns and assess associations with the objective and perceived retail food environment (RFE).

Design:
This cross-sectional study used principal component analysis and hierarchical cluster analysis to identify grocery shopping patterns and logistic regression models to assess their associations with the RFE, while adjusting for household characteristics.

Setting:
The Montpellier Metropolitan Area, France.

Participants:
To be eligible for inclusion, participants had to be 18 years of age or older and reside in the Montpellier Metropolitan Area. Analyses were carried out on 415 households.

Results:
Households of cluster ‘Supermarket’ (49 % of households) primarily shopped at supermarkets and were less likely to live near a convenience store. Households of cluster ‘Diversified’ (18 %) shopped mostly at organic stores, at markets, at specialised stores, and from producers and were more likely to have a market in their activity space. Households of cluster ‘Discount’ (12 %) primarily shopped at discounters and were less likely to perceive a producer in their activity space. Households of cluster ‘Convenience’ (12 %) mostly shopped online or in convenience stores. Finally, households of cluster ‘Specialized’ (9 %) had high expenditures in greengrocers and in other specialised food stores and were more likely to live near a specialised food store.

Conclusions:
This study highlighted the importance of considering both perceived and objective RFE indicators, as well as assessments around the home and in activity space. Understanding how people buy food and interact with their RFE is crucial for policymakers seeking to improve urban food policies.
Development and validation of a questionnaire to explore preferences of patients, family caregivers, and kidney care providers on advance care planning in an end-stage kidney disease setting
Authors: Naik Bharathi , Singhai Pankaj , Damani Anuja , Prabhu Attur Ravindra , Salins Naveen , Naik Prathvi , Nayak Ajith M. , Nagaraju Shankar Prasad 
Published: December 2023

AbstractObjectivesTo develop and validate an English and Kannada version of the questionnaire to assess awareness and knowledge of advance care planning (ACP) among end-stage kidney disease (ESKD) patients, caregivers, and healthcare providers.MethodsThe questionnaire was developed from the published literature on ACP use in ESKD setting after a literature search. An expert panel consisting of nephrologists, palliative medicine physicians, ESKD patients, and their family caregivers participated in the content validity of the questionnaire using the Delphi process. The study was conducted between August 2021 and July 2022 at a tertiary care hospital in India. A validated questionnaire was administered to eligible 30 ESKD patients, 30 caregivers, and 10 health care professionals. A retest was carried out 1 week after the first administration.ResultsThe content validity ratio of patient, caregiver, and health care professions questions ranged from 0.6 to 1 and Cronbach’s α value was 0.737 to 0.925. The intraclass correlation coefficient values for the test–retest of all three sections of this questionnaire varied from 0.879 to 0.972.Significance of resultsThe developed questionnaire is a reliable and valid method for assessing the preference and knowledge of ACP in ESKD patients, family caregivers, and kidney care providers both in English and Kannada.
Impact of Convection‐Permitting and Model Resolution on the Simulation of Mesoscale Convective System Properties Over East Asia
Authors: Ding Tian , Guo Zhun , Zou Liwei , Zhou Tianjun 
Published: December 2023

AbstractIn this study, two limited‐area convection‐permitting models (ICON‐CPMs) and convection‐parameterized models (ICON‐CParMs) covering the Asia monsoon region from ICOsahedral Nonhydrostatic model are conducted to investigate the sensitivities of Mesoscale Convective Systems (MCSs) to convection configurations and horizontal resolutions. We find that ICON‐CPMs outperform ICON‐CParMs and ERA5 in number, lifetime, size, shape, orientation, effective speed, and MCS‐mean precipitation. Compared to the satellite observation, MCSs in ICON‐CParMs and ERA5 are oversized (30%–66%) and have longer (21%–29%) lifetimes but occur less (37%–46%) frequently. When turning off the convection scheme, performances are improved to a large extent. The underestimation of MCS‐mean precipitation rates in ICON‐CParMs and ERA5 are improved in ICON‐CPMs. Moisture budgets show that low‐level winds rather than moisture determine the strength of MCS‐mean precipitation rate. The strong low‐level convergence produces strong updrafts in ICON‐CPMs and eventually results in strong MCS precipitation. The overly intense convective precipitation of MCSs in CPMs is an inherent problem since the scale of convection triggered at the gray zone grid spacing is larger than that in the real world. Although the MCS‐mean precipitation rate is closer to the satellite observation in ICON‐CPMs, it is actually a compensation for overly strong convective precipitation and overly weak stratiform precipitation. Upgrading resolution from 8 to 4 km in ICON‐CPMs has benefits in simulating MCS lifetime, size, shape, orientation, and precipitation but not in MCS number.
Modeling “Wrong Side” Failures Caused by Geomagnetically Induced Currents in Electrified Railway Signaling Systems in the UK
Authors: Patterson C. J. , Wild J. A. , Boteler D. H. 
Published: December 2023

AbstractThe majority of studies into space weather impacts on ground‐based systems focus on power supply networks and oil and gas pipelines. The effects on railway signaling infrastructure remain a sparsely covered aspect even though these systems are known to have experienced adverse effects in the past as a result of geomagnetic activity. This study extends recent modeling of geomagnetic effects on DC signaling for AC‐electrified railways in the UK that analyzed “right side” failures in which green signals are turned to red. The extended model reported here allows the study of “wrong side” failures where red signals are turned green: a failure mode that is potentially more dangerous. Railway lines using track circuit signaling, like those modeled in this study, are separated into a number of individual blocks. This study shows that a relay is most susceptible to “wrong side” failure when a train is at the end of a track circuit block. Assuming that each train is positioned at the end of the block it is occupying, the results show that the geoelectric field threshold at which “wrong side” failures can occur is lower than for “right side” failures. This misoperation field level occurs on a timescale of once every 10 or 20 years. We also show that the estimated electric field caused by a 1‐in‐100 years event could cause a significant number of “wrong side” failures at multiple points along the railway lines studied, although this depends on the number of trains on the line at that time.
The association between urban land use and depressive symptoms in young adulthood: a FinnTwin12 cohort study
Authors: Wang Zhiyang , Whipp Alyce M. , Heinonen-Guzejev Marja , Foraster Maria , Júlvez Jordi , Kaprio Jaakko 
Published: December 2023

Abstract
Background
Depressive symptoms lead to a serious public health burden and are considerably affected by the environment. Land use, describing the urban living environment, influences mental health, but complex relationship assessment is rare.

Objective
We aimed to examine the complicated association between urban land use and depressive symptoms among young adults with differential land use environments, by applying multiple models.

Methods
We included 1804 individual twins from the FinnTwin12 cohort, living in urban areas in 2012. There were eight types of land use exposures in three buffer radii. The depressive symptoms were assessed through the General Behavior Inventory (GBI) in young adulthood (mean age: 24.1). First, K-means clustering was performed to distinguish participants with differential land use environments. Then, linear elastic net penalized regression and eXtreme Gradient Boosting (XGBoost) were used to reduce dimensions or prioritize for importance and examine the linear and nonlinear relationships.

Results
Two clusters were identified: one is more typical of city centers and another of suburban areas. A heterogeneous pattern in results was detected from the linear elastic net penalized regression model among the overall sample and the two separated clusters. Agricultural residential land use in a 100 m buffer contributed to GBI most (coefficient: 0.097) in the “suburban” cluster among 11 selected exposures after adjustment with demographic covariates. In the “city center” cluster, none of the land use exposures was associated with GBI, even after further adjustment with social indicators. From the XGBoost models, we observed that ranks of the importance of land use exposures on GBI and their nonlinear relationships are also heterogeneous in the two clusters.

Impact

This study examined the complex relationship between urban land use and depressive symptoms among young adults in Finland. Based on the FinnTwin12 cohort, two distinct clusters of participants were identified with different urban land use environments at first. We then employed two pluralistic models, elastic net penalized regression and XGBoost, and revealed both linear and nonlinear relationships between urban land use and depressive symptoms, which also varied in the two clusters. The findings suggest that analyses, involving land use and the broader environmental profile, should consider aspects such as population heterogeneity and linearity for comprehensive assessment in the future.
Entanglement monogamy in indistinguishable particle systems
Authors: Das Soumya , Paul Goutam , Sengupta Ritabrata 
Published: December 2023

AbstractRecently, it has been realized that indistinguishability is a resource for quantum information processing. A new method to represent the indistinguishable particles by Franco et al. (Sci Rep 6:20603, 2016, https://doi.org/10.1038/srep20603) and measure the concurrence is developed by Nosrati et al. (npj Quantum Inf 6:39, 2020, https://doi.org/10.1038/s41534-020-0271-7). The monogamy property says that quantum entanglement cannot be shared freely between more than two particles. For three distinguishable particles, the monogamy of entanglement was first expressed as an inequality using squared concurrence where each particle has a single degree of freedom (for pure or mixed states). Using multiple degrees of freedom, similar inequality was shown to be held between two distinguishable particles. However, for two indistinguishable particles, where each particle cannot be addressed individually, the monogamy inequality was shown to be violated maximally for a specific state. Thus a question naturally arises: what happens to the monogamy of entanglement in the case of three or more indistinguishable particles? We prove that monogamy holds in this scenario and the inequality becomes equality for all pure indistinguishable states. Further, we provide three major operational meanings of our result. Finally, we present an experimental schematic using photons to observe our result.
Computational study of a co-infection model of HIV/AIDS and hepatitis C virus models
Authors: Dayan Fazal , Ahmed Nauman , Bariq Abdul , Akgül Ali , Jawaz Muhammad , Rafiq Muhammad , Raza Ali 
Published: December 2023

AbstractHepatitis C infection and HIV/AIDS contaminations are normal in certain areas of the world, and because of their geographic overlap, co-infection can’t be precluded as the two illnesses have a similar transmission course. This current work presents a co-infection model of HIV/AIDS and Hepatitis C virus with fuzzy parameters. The application of fuzzy theory aids in tackling the issues associated with measuring uncertainty in the mathematical depiction of diseases. The fuzzy reproduction number and fuzzy equilibrium points have been determined in this context, focusing on a model applicable to a specific group defined by a triangular membership function. Furthermore, for the model, a fuzzy non-standard finite difference (NSFD) technique has been developed, and its convergence is examined within a fuzzy framework. The suggested model is numerically validated, confirming the dependability of the devised NSFD technique, which successfully retains all of the key properties of a continuous dynamical system.
Clinical characteristics of Long COVID patients presenting to a dedicated academic post-COVID-19 clinic in Central Texas
Authors: Aziz Rija , Siles Nadia , Kelley Mary , Wylie Dennis , Melamed Esther , Brode W. Michael 
Published: December 2023

AbstractPost-acute sequelae SARS-CoV-2 (PASC), also known as Long COVID, is a complex and widely recognized illness with estimates ranging from 5 to 30% of all COVID-19 cases. We performed a retrospective chart review of patients who presented to a dedicated Post-COVID-19 clinic between June 2021 and May 2022. The median patient age was 44.5 years, 63.5% patients were female, and patients presented at a median of 10.4 months from acute COVD-19 infection. 78% self-identified their race as white, and 21% identified as Latino ethnicity. During the acute COVID-19 infection, 50% of patients experienced moderate disease severity and 10.5% were hospitalized. The top three co-morbid conditions prior to SARS-CoV-2 infection included mental health conditions, hypertension and asthma. Patients reported a median of 18 new symptoms following COVID-19 illness, the most common were fatigue (89%), forgetfulness or “brain fog” (89%), and difficulty concentrating (77%). MoCA (Montreal Cognitive Assessment) assessment demonstrated that 46% had mild cognitive dysfunction. PHQ-9 (Patient Health Questionnaire) testing revealed 42% had moderate to severe depression, and 38% had moderate to severe anxiety on the GAD-7 (Generalized Anxiety Disorder) assessment. Symptom burden was similar across gender, age, and initial disease severity. PASC patients presenting to an academic Post-COVID-19 clinic experienced numerous multisystem symptoms and functional impairment, independent of the initial COVID-19 disease severity.
Genetic and clinical characteristics of PROM1-related retinal degeneration in Korean
Authors: Hwang Sungsoon , Kang Se Woong , Jang Ja-Hyun , Kim Sang Jin 
Published: December 2023

AbstractThis scientific report aims to comprehensively describe the genetic and clinical characteristics of PROM1-related retinal degeneration in Korean patients. Medical records of patients diagnosed with retinal dystrophy who underwent comprehensive ophthalmologic examination and genetic testing at Samsung Medical Center between January 2016 and April 2023 were retrospectively reviewed. Genetic testing included targeted gene panel sequencing and Sanger sequencing, with diagnosis based on the presence of a “Likely Pathogenic” or “Pathogenic Variant” in the PROM1 gene, as determined by the ACMG criteria. The study identified seven patients from five unrelated families with PROM1-related retinal degeneration, all carrying the autosomal dominant variant PROM1 p.R373C; no other PROM1 gene variants were detected. All patients exhibited degenerative retinal area within the macula, with peripheral retinal degeneration observed in five patients. Substantial interfamilial and intrafamilial variability was observed in the extent of macular and peripheral degeneration. Ultra-widefield autofluorescence imaging and fluorescein angiography aided in the detection of mild peripheral degeneration in one case. In conclusion, the autosomal dominant variant PROM1 p.R373C constitutes a significant proportion of PROM1-related retinal degeneration cases in the Korean population. The observed clinical heterogeneity may suggests the potential influence of additional genetic, epigenetic, and environmental factors on disease phenotypes.
Sustainable road network design considering hydrogen fuel cell vehicles
Authors: Liu Hongxi 
Published: December 2023

AbstractEnvironmental pollution and energy shortages have brought about an increased focus on new energy vehicles. Hydrogen fuel cell vehicles (HFCVs) have experienced rapid development due to the potential to alleviate energy pressures and reduce pollution emissions. Near zero-carbon emissions offer a promising avenue for promoting sustainable transportation development. To evaluate the impact of HFCVs on the transportation environment, this paper investigates the problem of sustainable transportation network design including HFCVs. Specifically, the problem is formulated as a bi-level multi-objective programming problem, with the upper level aimed at determining the optimal network design scheme considering multiple objectives, while the lower level addresses the mixed traffic flow that comprises both HFCVs and fuel vehicles. To solve the multi-objective sustainable network design problem, an integrated solution framework that combines the particle swarm optimization (PSO) algorithm with the Frank-Wolfe algorithm (FW) is developed. Specifically, the PSO algorithm is utilized to solve the upper-level model and identify the optimal network design schemes, while FW algorithm is adopted to handle mixed traffic flow assignments. Finally, the proposed model and algorithm are implemented in two numerical experiment to demonstrate their effectiveness and efficiency.
Latent inter-organ mechanism of idiopathic pulmonary fibrosis unveiled by a generative computational approach
Authors: Kozawa Satoshi , Tejima Kengo , Takagi Shunki , Kuroda Masataka , Nogami-Itoh Mari , Kitamura Hideya , Niwa Takashi , Ogura Takashi , Natsume-Kitatani Yayoi , Sato Thomas N. 
Published: December 2023

AbstractIdiopathic pulmonary fibrosis (IPF) is a chronic and progressive disease characterized by complex lung pathogenesis affecting approximately three million people worldwide. While the molecular and cellular details of the IPF mechanism is emerging, our current understanding is centered around the lung itself. On the other hand, many human diseases are the products of complex multi-organ interactions. Hence, we postulate that a dysfunctional crosstalk of the lung with other organs plays a causative role in the onset, progression and/or complications of IPF. In this study, we employed a generative computational approach to identify such inter-organ mechanism of IPF. This approach found unexpected molecular relatedness of IPF to neoplasm, diabetes, Alzheimer’s disease, obesity, atherosclerosis, and arteriosclerosis. Furthermore, as a potential mechanism underlying this relatedness, we uncovered a putative molecular crosstalk system across the lung and the liver. In this inter-organ system, a secreted protein, kininogen 1, from hepatocytes in the liver interacts with its receptor, bradykinin receptor B1 in the lung. This ligand–receptor interaction across the liver and the lung leads to the activation of calmodulin pathways in the lung, leading to the activation of interleukin 6 and phosphoenolpyruvate carboxykinase 1 pathway across these organs. Importantly, we retrospectively identified several pre-clinical and clinical evidence supporting this inter-organ mechanism of IPF. In conclusion, such feedforward and feedback loop system across the lung and the liver provides a unique opportunity for the development of the treatment and/or diagnosis of IPF. Furthermore, the result illustrates a generative computational framework for machine-mediated synthesis of mechanisms that facilitates and complements the traditional experimental approaches in biomedical sciences.