bluuebunny/crossref_metadata_2025_split huggingface dataset:
Feasibility and uptake of a digital mental health intervention for depression among Lebanese and Syrian displaced people in Lebanon: a qualitative study
Authors: Abi Ramia Jinane , Abi Hana Racha , Noun Philip , Cuijpers Pim , Carswell Kenneth , van't Hof Edith , Heim Eva , Zoghbi Edwina , Sijbrandij Marit , El Chammay Rabih 
Published: January 2024

IntroductionDigital interventions are increasingly regarded as a potential solution for the inaccessibility of mental health treatment across low-and-middle-income settings, especially for common mental disorders. Step-by-Step (SbS) is a digital, guided self-help intervention for depression found effective in two Randomized Controlled Trials (RCTs) in Lebanon. For research implementation and further scale-up, this paper reports the results of a qualitative evaluation of SbS among the Lebanese and others and displaced Syrians in Lebanon.MethodsThirty-four Key Informant Interviews (KIIs) were executed with participants of the RCTs, SbS staff members, and external stakeholders. Questions garnered feedback about the feasibility, acceptability, enabling factors, and barriers to adhering to the research, implementation, and the SbS intervention. A thematic analysis was conducted using NVivo, and key themes, topics, and recommendations, on research methods and the intervention itself, were generated and reported.ResultsResults showed a high level of acceptability of SbS among Lebanese and Syrians and identified sub-groups for whom acceptance or use might be lower, such as older adults and people with limited access to the internet or smartphones. Furthermore, interviews identified the main enabling factors and barriers to adherence related to the research design, content, and delivery approach. Barriers related to feasibility included lengthy assessments as part of the RCTs, and mistrust related to delays in study compensations. Other common challenges were forgetting login credentials, poor internet connection, being busy and competing needs. Enabling factors and best practices included motivating participants to use the intervention through the weekly support provided by helpers, setting an oral contract for commitment, and dividing the compensations into several installments as part of the RCTs. Recommendations regarding sustainability were given.DiscussionThe findings show that overall, SbS is feasible, acceptable, and much needed in Lebanon among the Lebanese and Syrians. This assessment identifies reasons for low adherence to the research and the intervention and presents improvement solutions. Recommendations generated in this paper inform the upscale of SbS and the planning, design, and implementation of future digital interventions in research and service provision settings in the mental health field.
Add-on effects of oral tocopherol supplementation to surgical varicocelectomy on the outcome of assisted reproductive technology: a single-center pilot study report
Authors: Takeshima Teppei , Mihara Takahiro , Tomita Makoto , Kuroda Shinnosuke , Yumura Yasushi , Ueno Hiroe , Yamamoto Mizuki , Murase Mariko 
Published: January 2024

IntroductionVaricocelectomy is well known to improve the pregnancy outcome of patients with clinical varicoceles in assisted reproductive technologies as well as spontaneous conception. Therefore, this study aimed to evaluate the additional effects of oral antioxidant therapy after varicocelectomy on the pregnancy outcome in the assisted reproductive technology setting.MethodsThis study was a retrospective cohort study. The subjects were couples among whom the male partner had undergone varicocelectomy and was scheduled for subsequent assisted reproductive technology. Pregnancy outcomes were followed retrospectively in 62 couples with male partners who received tocopherol (antioxidant group) and 37 couples who did not (control group). The tocopherol and control groups were assigned dependent on the decision of the physician in charge and the patient's request. The clinical pregnancy rates per couple and embryo transfer, time to pregnancy, and the number of cycles during transfer to pregnancy were evaluated.ResultsNo significant differences were observed in the pregnancy rate per couple (antioxidant group 70.9% vs. control group 64.9%, P = 0.55) and per embryo transfer (50.4% vs. 39.6%, P = 0.22). Regarding the time to event analyzed by adjusted restricted mean survival time, the mean time to pregnancy was significantly shorter in the antioxidant (tocopherol) group (14.2 vs. 17.4 months, P = 0.025). No significant difference was observed in the embryo transfer cycle to pregnancy (mean embryo transfer cycles: 2.6 vs. 3.0, P = 0.238).ConclusionsAdditional oral tocopherol nicotinate as antioxidant therapy after varicocelectomy was shown to shorten the time to pregnancy. It is recommended that add-on effects be tested in more well-designed randomized controlled trials to examine whether it improves assisted reproductive outcomes.
Gross motor proficiency deficits among children and adolescents post posterior fossa brain tumor removal vs. traumatic brain injury in the chronic phase of recovery: a cross-sectional study
Authors: Barak Sharon , Brezner Amichai , Yissar Tamar , Eisenstein Etzyona , Ackerman-Laufer Shirley , Landa Jana 
Published: January 2024

IntroductionAcquired brain injury (ABI) is a prevalent diagnosis in pediatric rehabilitation. Gross motor skills are often affected by ABI and limit the ability to participate in various physical activities. However, as ABI injury location is diverse, children and adolescents (youth) with localized ABI, such as ABI in the posterior fossa (ABI-PF) may present unique and different motor disabilities than youth with ABI on account of traumatic brain injury (TBI).AimsThe aims of the study were: (1) to compare gross motor deficits in youth with TBI vs. ABI-PF; and (2) to compare two methods on scoring BOT2 to determine which is better for identifying motor deficits.MethodsParticipated in this study youth with TBI (N = 50) and ABI-PF (N = 30). Participants were tested on Bruininks-Oseretsky Test of Motor Proficiency-2nd Edition (BOT2) Upper-Limb Coordination, Balance, Strength, Running Speed and Agility, and Bilateral-Coordination subtests. Motor performance deficits were established using two-standard deviations (2SD) and age-equivalent methods. Between-group differences were assessed via independent t-tests and receiver operating characteristic curves (ROC).ResultsAccording to the 2SD method, motor deficits in the ABI-PF group ranged from 20% to 66.66%, whereas in the TBI group 8%–16%. According to the age-equivalent method, in the TBI and ABI-PF groups 40%–66.0% and 46.66%–76.66% of the youth presented motor deficits, respectively. Moreover, ROC analysis showed that motor performance deficits of both groups in all sub-scales except for Bilateral Coordination differed enough to result in medium area under the curve.ConclusionsMotor deficits post-pediatric ABI are prevalent. In comparison to the TBI group, deficits are greater in the ABI-PF group. Moreover, compared to the 2SD method, the extent of motor deficiency is greater in the age-equivalent method. Therefore, using the later might provide a more valid classification of deficits in gross motor proficiency for youth post-ABI.
Cochlear implant positioning: development and validation of an automatic method using computed tomography image analysis
Authors: Kemper Erik H. M. , Markodimitraki Laura M. , Magré Joëll , Simons Dominique C. , Thomeer Hans G. X. M. 
Published: January 2024

The aim of this study was to preoperatively asses the feasibility of drilling a bony recess for the fixation of a cochlear implant in the temporal bone. Even though complications are rare with cochlear implantations, drilling at the site of implantation have resulted in hematoma or cerebrospinal fluid leakage. Mainly in cases with a reduced temporal bone thickness, the risk for complications has increased, such as in paediatric patients.MethodsAn in-house designed semi-automatic algorithm was developed to analyse a 3D model of the skull. The feasibility of drilling the recess was determined by a gradient descent method to search for the thickest part of the temporal bone. Feasibility was determined by the residual bone thickness which was calculated after a simulated drilling of the recess at the thickest position. An initial validation of the algorithm was performed by measuring the accuracy of the algorithm on five 3D models with known thickest locations for the recess. The accuracy was determined by a part comparison between the known position and algorithm provided position.ResultsIn four of the five validation models a standard deviation for accuracy below the predetermined cut-off value of 4.2 mm was achieved between the actual thickest position and the position determined by the algorithm. Furthermore, the residual thickness calculated by the algorithm showed a high agreement (max. 0.02 mm difference) with the actual thickness.ConclusionWith the developed algorithm, a semi-automatic method was created to analyse the temporal bone thickness within a specified region of interest on the skull. Thereby, providing indications for surgical feasibility, potential risks for anatomical structures and impact on procedure time of cochlear implantation. This method could be a valuable research tool to objectively assess feasibility of drilling a recess in patients with thin temporal bones preoperatively.
Anti-Fibrosis Effect of Panax ginseng and Inula japonica Formula in Human Pulmonary Fibroblasts
Authors: Jung YeonGyun , Yim Nam-Hui , Lee Sang Myung , Cho Won-Kyung , Cha Min Ho , Ma Jin Yeul 
Published: January 2024

Panax ginseng Meyer and Inula japonica Thunb. are well established in traditional medicine and are known for their therapeutic properties in managing a range of ailments such as diabetes, asthma, and cancer. Although P. ginseng and I. japonica can alleviate pulmonary fibrosis (PF), the anti-fibrosis effect on PF by the combination of two herbal medicines remains unexplored. Therefore, this study explores this combined effect. In conditions that were not cytotoxic, MRC-5 cells underwent treatment using the formula combining P. ginseng and I. japonica (ISE081), followed by stimulation with transforming growth factor (TGF)-β1, to explore the fibroblast-to-myofibroblast transition (FMT). After harvesting the cells, mRNA levels and protein expressions associated with inflammation and FMT-related markers were determined to evaluate the antiinflammation activities and antifibrosis effect of ISE081. Additionally, the anti-migratory effects of ISE081 were validated through a wound-healing assay. ISE081 remarkably reduced the mRNA levels of interleukin (IL)-6, IL-8, α-smooth muscle actin (SMA), and TGF-β1 in MRC-5 cells and suppressed the α-SMA and fibronectin expressions, respectively. Furthermore, ISE081 inhibited Smad2/3 phosphorylation and wound migration of MRC-5 cells. Under the same conditions, comparing those of ISE081, P. ginseng did not affect the expression of α-SMA, fibronectin, and Smad2/3 phosphorylation, whereas I. japonica significantly inhibited them but with cytotoxicity. The results indicate that the synergistic application of P. ginseng and I. japonica enhances the anti-fibrotic properties in pulmonary fibroblasts and concurrently diminishes toxicity. Therefore, ISE081 has the potential as a prevention and treatment herbal medicine for PF.
Cell Staining Microgels Derived from a Natural Phenolic Dye: Hematoxylin Has Intriguing Biomedical Potential
Authors: Sahiner Mehtap , Sunol Aydin K. , Sahiner Nurettin 
Published: January 2024

Hematoxylin (HT) as a natural phenolic dye compound is generally used together with eosin (E) dye as H&E in the histological staining of tissues. Here, we report for the first time the polymeric particle preparation from HT as poly(Hematoxylin) ((p(HT)) microgels via microemulsion method in a one-step using a benign crosslinker, glycerol diglycidyl ether (GDE). P(HT) microgels are about 10 µm and spherical in shape with a zeta potential value of −34.6 ± 2.8 mV and an isoelectric point (IEP) of pH 1.79. Interestingly, fluorescence properties of HT molecules were retained upon microgel formation, e.g., the fluorescence emission intensity of p(HT) at 343 nm was about 2.8 times less than that of the HT molecule at λex: 300 nm. P(HT) microgels are hydrolytically degradable and can be controlled by using an amount of crosslinker, GDE, e.g., about 40%, 20%, and 10% of p(HT) microgels was degraded in 15 days in aqueous environments for the microgels prepared at 100, 200, and 300% mole ratios of GDE to HT, respectively. Interestingly, HT molecules at 1000 mg/mL showed 22.7 + 0.4% cell viability whereas the p(HT) microgels exhibited a cell viability of 94.3 + 7.2% against fibroblast cells. Furthermore, even at 2000 mg/mL concentrations of HT and p(HT), the inhibition% of α-glucosidase enzyme were measured as 93.2 ± 0.3 and 81.3 ± 6.3%, respectively at a 0.03 unit/mL enzyme concentration, establishing some potential application of p(HT) microgels for neurogenerative diseases. Moreover, p(HT) microgels showed two times higher MBC values than HT molecules, e.g., 5.0 versus 2.5 mg/mL MIC values against Gram-negative E. coli and Gram-positive S. aureus, respectively.
Chemical mechanical polishing for indium bond pad damascene processing
Authors: Ceulemans Karl , Shafahian Ehsan , Struyf Herbert , Devriendt Katia , Deckers Steven , Heylen Nancy , Derakhshandeh Jaber 
Published: January 2024

Abstract
We investigated chemical mechanical polishing (CMP) of indium, with the goal of obtaining indium bond pads for later cryo-3D integration of quantum computing-related chips, through bonding between these bond pads and indium bumps. Higher removal rates were obtained with soft CMP pads than with hard pads. The latter led to deep scratching, while this effect was much more limited for soft pad CMP. On patterned wafers, indium is cleared well in structured areas using soft pad CMP, leading to relatively high-quality indium surfaces inside bond pads, although corrosion might be of some concern. Pattern density uniformity was an important factor for within-die deviation in indium clearing time. Dishing was much more limited than in earlier work on indium polishing, while surface roughness was also found to be relatively limited. The obtained indium damascene bond pads may be suitable for 3D die-to-die and wafer-to-wafer bonding through indium pad-to-bump bonding.
A new approach to assessing and forecasting the stock of sprat in the Baltic Sea in modern conditions
Authors: Amosova V. M. , Zezera A. S. 
Published: January 2024

The aim of this article: analysis of information and software for forecasting of the Baltic Sea sprat stock Sprattus sprattus balticus at 22–32 ICES subdivisions in the context of the suspension of Russia’s activities in the International Council for the Exploration of the Sea (ICES).Methods used: The data of estimates of sprat abundance and biomass by hydroacoustic methods, commercial and biostatistical characteristics of the species were used to assess the stock and predict its catch in the Baltic Sea. Estimation of the sprat stock was carried out using the traditional method of virtual population analysis (VPA) adjusted according to the method of extended survival analysis (XSA) using the internationally approved VPA module software within the framework of ICES and the R software environment. The recruitment calibration program RCT3 (Recruitment calibration) was used for the abundance of recruitment (age 1 year) according to XSA and forecast. A multivariate short-term forecast was carried out at different levels of development of the total allowable catch (TAC) under the MFDP program (Multi Fleet Deterministic Projection). As an alternative, the domestic software «KAFKA» was tested.Novelty: for the first time, estimates of the sprat stock were made in the conditions of limited access of Russian specialists to primary data in ICES in full.Result: modern methodological and informational support of scientific research in the Baltic Sea in the conditions of the suspension of the activities of Russian experts in ICES makes it possible to obtain information in the minimum necessary amount for assessing the stock of sprat and predicting its catch. Modeling with the «KAFKA» software showed satisfactory results.Practical significance: The current level of information support for forecasting the state of the stock and catch of sprat in the Baltic Sea will allow solving a complex of problems of managing this resource in modern conditions.
To the assessment of green sea urchin stocks in the coastal zone of the Barents Sea
Authors: Labutin A. V. , Shatsky A. V. , Buyanovsky A. I. 
Published: January 2024

The purpose of the work is to assessment the state of stocks of the green sea urchin (Strongylocentrotus droebachiensis) in the coastal zone of the Barents Sea.Methods used — to achieve the set goal, standard methods for collecting hydrobiological material and calculating the abundance and biomass of hydrobionts were used.Novelty — the data obtained as a result of the research made it possible to update information on the state of the green sea urchin stocks on the coasts of Western and Eastern Murman.Results — the total and commercial reserves of sea urchin were determined on an area of 2812 thousand m2. The total stock of sea urchins was 3.58 thousand tons, the commercial one — 2.17 thousand tons. The total density of urchins in the studied water area was 32 specimens/m², the commercial one — 10.3 specimens/m². The most promising areas for fishing have been identified.Practical significance — thanks to the use of the research results, adding them to materials from other sources, it will be possible to more accurately predict the volumes and timing of fishing. Mining companies will receive more complete information about promising fishing areas and possible catch volumes.
The dynamics of arabesque greenling fishery off south Kuril Islands
Authors: Kim Sen Tok 
Published: January 2024

The purpose of this work was to characterize the biological and commercial indicators of arabesque greenling in the Kunashir Strait during 1998–2022.The basic material for the article was the data collected during the net fishery of arabesque greenling by the fleet of small-tonnage vessels of the Japanese fishing cooperative in the city of Rausu in the eastern (Russian) zone of the Kunashir Strait.Results: It is shown that the stock resources of arabesque greenling in the waters of the southern Kuril Islands have been declining during for a long period of time. Despite a short-term growth of catch per effort in 2018–2021, in 2022 there was again a decrease of fishery indicators. The negative trend of catch per effort is directly associated with the features of dynamics of arabesque greenling resources distributed in Kunashir Strait and in the Sea of Okhotsk waters of Hokkaido.Practical significance: The new information makes it possible to determine the current trends in total biomass changing for commercial fish and to clarify the fishery capabilities of the area in the nearest future.
ЗАХИСТ ПЕРСОНАЛЬНИХ ДАНИХ В УКРАЇНІ І В УГОРЩИНІ: ПОРІВНЯЛЬНИЙ АНАЛІЗ
Authors: Zhuravleva Iryna 
Published: January 2024

У статті аналізуються системи захисту персональних даних в Україні та її порівнянню з аналогічною системою в Угорщині. Відповідно у статті на комплексному рівні розглянуто сучасний стан законодавчого забезпечення захисту персональних даних в Україні та Угорщині, здійснено порівняльний аналіз нормативно-правового регулювання, а також оцінено ефективність заходів, спрямованих на забезпечення приватності громадян. Мета статті – розширити розуміння питань, пов’язаних із реалізацією різноаспектних механізмів забезпечення захисту персональних даних на прикладі порівняння сучасних аспектів захисту персональних даних в Україні та Угорщині. Було встановлено, що сучасні нормативно-правові та технічно-реалізаційні механізми захисту персональних даних в Україні та Угорщині є схожими. Однак між законодавчими нормами обох країн є деякі відмінності. Так, в угорських нормативно-законодавчих актах окреслюється більш широке визначення персональних даних, ніж українських. Зокрема, в Угорщині на законодавчому рівні передбачається більш жорсткі вимоги до повідомлення про порушення безпеки персональних даних і відповідно передбачено більш широкий спектр технічних заходів захисту персональних даних, ніж в Україні. Виявлена тенденція пов’язана з тим, що Угорщина є членом Європейського Союзу і повинна відповідати вимогам Регламенту GDPR. Аналіз захисту персональних даних в Україні та порівняння з практикою в Угорщині вказують на значущі виклики та перспективи у сфері конфіденційності громадянської інформації. Обидві країни визнають важливість відповідності європейським стандартам, проте відмінності у втіленні та ефективності заходів потребують уваги. Україна зосереджується на вдосконаленні законодавства та контролю, тоді як Угорщина активно розвиває систему кіберзахисту та намагається узгодити свої закони з європейськими. Подальше посилення освіти громадян щодо захисту персональних даних сприятиме створенню більш безпечного і цифрового суспільства в обох країнах.
"Study of leisure activities among students of the Faculty of Arts and Science – Al-Marj"
Authors: Badr Ahmed 
Published: January 2024

The study aims to identify the forms of leisure activities in students of the Faculty of Arts and Sciences, Al-marj as well as to identify the order of these activities according to importance and from the point of view of the sample, the researcher has relied during his study on the descriptive curriculum, and one of the most important results was that the highest activity in the axis of sports activities was PlayStation with an average of 2.60 and always in response and the lowest equestrian activity and an average of 1.60 and towards a response never, and the highest activity within the axis of cultural activities surfing the Internet with an average of 2.46 and in a direction of response always and the least activity writing and writing and writing and an average of 1.43 and towards the response Never, the highest activity within the center of artistic activities is watching television with an average of 2.53, with a constant response direction, less activity of fine arts, an average of 1.28 and a response rate of never, and the highest activity within the axis of social activities family meetings with an average of 2.41 and a constant response direction The lowest activity of scout ing activity with an average of 1.46 and a response direction never, and the highest activity within the activities of the activity of the cellular activities journeys with an average of 2.36 and the direction of the response always and the least activity of the camps and an average of 1.61 and towards the response never, and that the order of leisure activities according to the responses of the sample in The first playstation is an average of 2.60, always in response and less activity of fine arts, with an average of 1.28 and a response direction at all.
On Hyper Ideals of Γ – hypernear-ring
Authors: AbouElwan Yasser , Fanoush Mahmoud 
Published: January 2024

In 2010, hyperideals of Γ- hypernear-ring introduced by B. Davvaz [8]. In this paper, arbitrary union and intersection of a family of hyperideals of Γ- hypernear-ring is hyperideal of Γ- hypernear-ring are proved. This study showed that, the quotient Γ-hypernear-ring ( M/I, ⊕, ⊙ ) is Γ-hypernear-ring.
Key Words: near-ring, subnear-ring, hyperoperation, hypergroupoid, hypernear-rings, Γ – hypernear-ring, hyperideal of Γ – hypernear-ring, and Γ – hypernear-ring homomorphism.