bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid Posterior Capsular Opacification in Two Patients Treated for Negative Dysphotopsias
Authors: Navia Juan Carlos , Reategui Joaquin A. , Huang Jordan J. , Martinez Jaime D. 
Published: January 2024

Abstract

Background: Negative dysphotopsias (ND) are visual aberrations associated with in-the-bag optic intraocular lens (IOL) placement, causing arc-shaped or linear shadows. Reverse optic capture (ROC) is employed to prevent ND, yet it poses the risk of posterior capsular opacification (PCO) which usually develops within 2-5 years post-surgery due to the lens epithelial cells (LECs) proliferation and migration onto the posterior capsule. This can lead to a cloudy or hazy appearance in the visual field. Early identification of posterior capsular opacities is crucial to ensure timely intervention and minimize visual impairment.
Cases Presentations: Two cases of acute and rapidly progressive PCO following cataract extraction (CE) and IOL placement using the ROC technique to prevent ND are reported at the Bascom Palmer Eye Institute. At the two-week postoperative follow-up, both patients reported a significant progressive decrease in vision in the treated eye, and severe posterior capsular opacities were observed. A diagnosis of PCO was confirmed, and successful visual rehabilitation was achieved through the performance of ND:YAG laser capsulotomy without complications. This case series represents the first reported instances of patients developing PCO within two weeks of CE and IOL placement using the ROC technique.
Conclusions: This case series sheds light on the occurrence of posterior capsular opacities shortly after CE and IOL placement using the ROC technique. It highlights the importance of preoperative patient education, postoperative monitoring, and prompt management of potential complications in cataract surgery.
Comparison and benchmark of gut viral genomes detected from short- and long-read metagenomes
Authors: Wang Huarui , Sun Chuqing , Chen Jingchao , Zhao Xing-Ming , Chen Wei-Hua 
Published: January 2024

Abstract

Background
Metagenome-assembled viral genomes have significantly advanced the discovery and characterization of the human gut virome. However, we lack a comparative assessment of assembly tools on the efficacy of viral genome identification, particularly across Next Generation Sequencing (NGS) and Third Generation Sequencing (TGS) data.
Results
We evaluated the efficiency of NGS, TGS and hybrid assemblers for viral genome discovery using 95 viral-like particle (VLP) enriched fecal samples sequenced on both Illumina and PacBio platforms. MEGAHIT, metaFlye and hybridSPAdes emerged as the optimal choices for NGS, TGS and hybrid datasets, respectively. Notably, these assemblers produced distinctive viral genomes, demonstrating a remarkable degree of complementarity. By combining individual assembler results, we expanded the total number of non-redundant high-quality viral genomes by 4.43 ~ 11.8 fold compared to individual assemblers. Among them, viral genomes from NGS and TGS data have the least overlap, indicating the impact of data type on viral genome recovery. We also evaluated two binning methods, finding that CONCOCT incorporated more unrelated contigs into the same bins, while MetaBAT2 balanced inclusiveness and taxonomic consistency within bins.
Conclusions
Our findings highlight the challenges in metagenome-driven viral discovery, underscoring tool limitations. We recommend the simultaneous use multiple assemblers, and both short- and long-read sequencing if resources permit, and advocate the pressing need for specialized tools tailored to gut virome assembly. This study contributes essential insights for advancing viral genome research in the context of gut metagenomics.
Random Forests for Inflation Forecasting with Discretized Data and Integrated Moving and static Seasonality
A case study of Algeria
Authors: CHERFAOUI Yasmine , FALI Fatima 
Published: January 2024

Abstract
Accurately forecasting inflation fluctuations is critical for effective economic policy. This paper introduces a novel Random Forest (RF) approach that integrates both lunar and Gregorian month seasonality to enhance inflation prediction accuracy.In this paper discretized data are used to construct aggregated model, enabling analysis of categorical inflation representations. The RF models of this paper leverages month-on-month inflation alongside lunar and Gregorian month features to capture potential cyclical patterns beyond standard temporal trends. This framework to forecast both global and food inflation. Empirical findings suggests the effectiveness of incorporating diverse seasonality features and data representations within the RF framework, offering promising avenues for improving inflation forecasting accuracy and informing well-informed economic policy decisions.
Wilcoxon Nonparametric CFAR Scheme for Ship Detection in SAR Image
Authors: Meng Xiangwei 
Published: January 2024

Abstract

The parametric constant false alarm rate (CFAR) detection algorithms which are based on various statistical distributions, such as Gaussian, Gamma, Weibull, log-normal, G0 distribution, alpha-stable distribution, etc, are most widely used to detect the ship targets in SAR image at present. However, the clutter background in SAR images is complicated and variable. When the actual clutter background deviates from the assumed statistical distribution, the performance of the parametric CFAR detector will deteriorate. In addition to the parametric CFAR schemes, there is another class of nonparametric CFAR detectors which can maintain a constant false alarm rate for the target detection without the assumption of a known clutter distribution. In this work, the Wilcoxon nonparametric CFAR scheme for ship detection in SAR image is proposed and analyzed, and a closed form of the false alarm rate for the Wilcoxon nonparametric detector to determine the decision threshold is presented. By comparison with several typical parametric CFAR schemes on Radarsat-2, ICEYE-X6 and Gaofen-3 SAR images, the robustness of the Wilcoxon nonparametric detector to maintain a good false alarm performance in different detection backgrounds is revealed, and its detection performance for the weak ship in rough sea surface is improved to some extent. Moreover, the Wilcoxon nonparametric detector can suppress the false alarms resulting from the sidelobes at some degree and its detection speed is fast.
A Global Health Survey of People Who Vape but Never Smoked: Protocol for the VERITAS (Vaping Effects: Real-World International Surveillance) Study
Authors: Zamora Goicoechea Jeffrey , Boughner Allison , Cirion Lee Juan José , Mahajan Aman , Yeo Kurt , Sproga Maris , Patel Tasmin , Saitta Claudio , Russell Christopher , Coughlan Michael , Caponnetto Pasquale , Polosa Riccardo 
Published: January 2024

Background
There is only limited information about the health effects of regular vaping. Research on the health status of people who used to smoke faces the challenge that previous smoking may have caused unknown health effects. Only studies of people who vape but have never smoked combustible cigarettes can enable the detection of harms attributable to vaping. Large prospective studies of well-characterized electronic cigarette users with and without a history of combustible cigarette smoking are warranted to establish the long-term effects of regular vaping on respiratory health.

Objective
We will conduct a global cross-sectional survey of individuals from 6 world regions. Respiratory symptoms will be assessed using a validated questionnaire—the Respiratory Symptom Experience Scale (RSES). Current vapers who are nonusers of other tobacco or nicotine products will be compared with matched controls who are nonusers of vapes and other tobacco or nicotine products.

Methods
This will be a multicountry, cross-sectional internet-based survey of 750 adults aged ≥18 years who satisfy the criteria for inclusion in either a cohort of people who exclusively vape and who are nonusers of other tobacco or nicotine products (“vapers cohort”; target N=500) or a cohort of nonvapers who are also nonusers of other tobacco or nicotine products (“controls cohort”; target N=250). The primary end point of the study is the RSES score. RSES scores of people in the “vapers cohort” will be compared with those of people in the “controls cohort.” Additionally, the study will collect data to characterize patterns of vaping product use among the vapers cohort. Data collection will include information about the age initiation of using vape products, reasons for starting and continuing the use of vape products, specific types of products used, flavors and nicotine strengths of recently used products, as well as the frequency and intensity of product use in the past 30 days.

Results
Participant recruitment started in April 2023, and enrollment was completed by November 2023 with 748 participants. Results will be reported in 2024.

Conclusions
This will be the first study providing key insights into respiratory health effects associated with using electronic cigarettes in people who vape with no established use of combustible cigarettes or other tobacco or nicotine products.

International Registered Report Identifier (IRRID)
DERR1-10.2196/54236
nomenclatura chinanteca y la función social de la microtoponimia en Santiago Comaltepec, Oaxaca
Authors: Hernández Israel , Nakamoto Shun 
Published: January 2024

La lengua de la comunidad chinanteca de Santiago Comaltepec, Ixtlán, Oaxaca, en México, posee una alta densidad de microtopónimos, con los que se refieren a pequeñas partes dentro de la población, y con los que dividen una superficie de 35 ha en, al menos, 56 partes pequeñas, a tal grado que a menudo un nombre corresponde a un área habitada por una o dos familias. En este estudio, documentamos tales designaciones de lugar a través de los relatos orales grabados en un acervo de documentación lingüísica y analizamos su estructura lingüística así como la correspondencia ontológica entre los términos fisiográficos y el entorno actual. De ese modo, demostramos que i) los microtopónimos chinantecos de Santiago Comaltepec incluyen más de veinte términos con etimología desconocida; ii) la mayoría de los microtopónimos se forman más bien alrededor de un término de relieve o de monumento, y no de la flora y la fauna u otro tipo de información ambiental; iii) los microtopónimos forman una subclase léxica cerrada que se distinguen de las descripciones momentáneas de lugares en términos de la ubicación relativa a un monumento; y iv) los microtopónimos tienen la función de identificar a individuos y se usan en diferentes momentos de la vida social en Santiago Comaltepec. Posteriormente, describimos la nomenclatura de los topónimos menores. Éstos difieren de los microtopónimos en i) incluir términos de relieve adicionales que se refieren a formaciones geográficas grandes, ii) incluir con frecuencia términos de flora y fauna e iii) incluir términos que describen condiciones climáticas. El resultado resalta la importancia de las perspectivas lingüística y social para estudiar los topónimos en general.
EFEKTIVITAS KEBIJAKAN FISKAL DAN KEBIJAKAN MONETER DALAM MENGATASI INFLASI DI INDONESIA PERIODE 1984-2019
Authors: Paramita Rastri 
Published: January 2024

This research was conducted to determine the effectiveness of fiscal and monetary policy in dealing with inflation in Indonesia in the 1984-2019 period. The variables that serve as a proxy for fiscal policy are government spending (rBP) and tax revenue (rPP). Meanwhile, the proxies for monetary policy are the Indonesian interest rate (rSBI) and the exchange rate (rKurs). By using a quantitative methodology, VECM analysis tools is conducted because the variables are cointegrated but stationary in the first difference. The result of this study is the impulse response function (IRF) shows the shock of fiscal policy is responded more quicklyby inflation to achieve a level of stability than the shock given by monetary policy. Based on the results of the variance decomposition (VD) test, the rBP variable had the largest contribution of 89.15 percent to inflation. Meanwhile, rPP contributed 1.12 percent, RSBI contributed 0.01 percent, and rKurs contributed 8.21 percent to inflation. So that based on the results of the VECM test on the effectiveness of fiscal policy and monetary policy on inflation control for the 1984-2019 period, it is found that fiscal policy has greater effectiveness than monetary policy on controlling inflation.
Pengaruh Pelatihan Dan Teknologi Penginderaan Jauh Terhadap Kualitas Salah Satu Komponen Intelijen Geospasial
Authors: Setiawan Sony , Pujo Widodo  , Djoko Andreas Navalino  
Published: January 2024

Pemanfaatan teknologi kecerdasan informasi spasial atau dikenal dengan geospasial intelijen menjadi populer digunakan dalam mencari informasi komponen strategis salah satuya adalah informasi mengenai pangkalan militer. Penelitian ini memiliki tujuan mengetahui dan menganalisis dampak pengaruh pelatihan dan teknologi penginderaan jauh terhadap kualitas salah satu komponen intelijen geospasial (foto udara pangkalan militer). Populasi penelitian ini adalah seluruh personel khusus pemotretan udara di salah satu unit militer di Jakarta yang berjumlah 86 orang. Adapun teknik pengambilan sampel menggunakan teknik sensus, dengan mengambil 100% jumlah populasi yang ada di unit tersebut, yaitu sebanyak 86 responden. Pada pengumpulan data digunakan metode dengan melakukan studi dokumentasi literature dan kuisioner. Model analisis data yang digunakan adalah regresi linier berganda dengan menggunakan software Ms Excel dan SPSS 24. Kuesioner sebagai instrumen penelitian divalidasi dengan korelasi Pearson (Product Moment) sementara reliabilitas instrumen diukur dengan Cronbach Alpha. Hasil penelitian menunjukkan nilai koefisien determinasi (R) sebesar 83.70%, disimpulkan bahwa kemampuan variabel independen (pelatihan dan teknologi penginderaan jauh) menjelaskan pengaruhnya terhadap variabel dependen (kualitas foto udara pangkalan militer) sebesar 83.70%, sedangkan sisanya merupakan variabel yang tidak terungkap. Temuan penelitian adalah (1) pelatihan memiliki pengaruh positif terhadap hasil kualitas foto udara; (2) teknologi penginderaan jauh memiliki dampak pengaruh positif terhadap kualitas foto udara; (3) pelatihan dan penginderaan jauh memiliki dampak pengaruh positif terhadap hasil kualitas foto udara secara simultan. Kualitas foto udara lebih ditingkatkan oleh teknologi penginderaan jauh daripada pelatihan. Oleh karena itu, penggunaan sensor harus mengikuti kaidah fotogrametri dan tujuan pemetaan, sehingga dapat menghasilkan informasi foto udara yang lebih akurat dan presisi.
Adverse events for biologics in patients with CRSwNP: A meta-analysis
Authors: Shen Yang , Chang Lei , Lv Lan 
Published: January 2024

Immunoglobulin E (IgE) is a key mediator for the immune reaction in
airway mucosa and plays a vital role in nasal polyposis(NP). We review
the most recent evidence for the local IgE’s characteristics, the
modulation of its synthesis and function in NPs. The level of local IgE
is significantly elevated in polyps independently of IgE serum levels
and atopic status. Furthermore, local IgE is polyclonal and functional,
which is correlated with type 2 inflammation. IgE is produced by active
B cell and dependent on the classing switch recombination(CSR). In NPs,
this process is triggered by not only allergens but also microbial
colonization, especially the superantigen- Staphylococcus aureus. The
production of local IgE is modulated by lymphocytes, cytokines,
transcription factors and B cell intrinsic factor. Due to the central
role of IgE in NPs, it is regarded as an ideal target for therapy and
has been proved to be clinically successful. Based on this knowledge, we
believe that exploring the trigger and regulatory factors for the
activation of local B cells and CSR to IgE will provide more valuable
information for us to recognize the pathological mechanisms of local IgE
and offer the possible option for new therapeutic targets of NPs.
Comparison of amlodipine versus nifedipine for hypertension during pregnancy: a systematic review and meta-analysis
Authors: Yin Jin jin , Mei zhengrong , Shi shengying , Du Peili , Qin Shumin 
Published: January 2024

Backgroud: There is a lack of sufficient evidence regarding efficacy and
safety of amlodipine on treating hypertension during pregnancy.
Objective: To compare the efficacy and safety of amlodipine with
nifedipine on hypertension during pregnancy. Search strategy: PubMed,
Embase, Cochrane Library, clinicaltrials.gov, Chinese National Knowledge
Infrastructure, Wanfang Database and China Biology Medicine disc were
searched from inception to April l5, 2021. Selection criteria:
Randomised controlled trials were included. Data collection and
analysis: Data extraction was carried out by one researcher and checked
by another. Results were reported as risk ratios (RR) for dichotomous
outcomes or mean differences (MD) for continuous outcomes, with 95%
confidence intervals (CI). Results: Seventeen RCTs were included.
Amlodipine was found the efficacy is slightly superior to nifedipine on
treating hypertension during pregnancy (RR 1.06, 95% CI 1.01 to 1.10)
with a decreased risk for maternal side effects (RR 0.42, 95% CI 0.29
to 0.61). Subgroup analysis found amlodipine can get a better control on
SBP (RR -11.68, 95% CI -17.98 to -5.37) and DBP (RR -7.44, 95% CI
-13.81 to -1.06) compared with extended release nifedipine. In addition,
there was no difference between amlodipine and nifedipine on pregnancy
outcomes including caesarean section, premature labour, placental
abruption, FGR, fetal distress, neonatal asphyxia. Conclusions: Given
the results of this systematic review and meta-analysis, amlodipine can
be effectively and safely used for hypertension during pregnancy. Key
words: Amlodipine, Nifedipine, Hypertension during pregnancy,
Meta-analysis Tweetable abstract: This review found that amlodipine is
noninferior to nifedipine in managing hypertension during pregnancy.
Simultaneous Detection and Identification of Peste des petits ruminants Virus Types Ⅱ and Ⅳ by MCA-Based Real-Time RT-qPCR Assay within Single Reaction
Authors: Tang Jingyu , Du Hanyu , Jia Nannan , Tang Aoxing , Li Chuanfeng , Meng Chunchun , Liu Guangqing 
Published: January 2024

Peste des petits ruminants (PPR) disease is a cross-species infectious
disease that severely affects small ruminants and causes great losses to
livestock industries in various countries. Distinguishing
vaccine-immunized animals from naturally infected animals is an
important prerequisite for the eradication of PPR.
[ ](javascript:void(0);)Although peste des petits ruminants virus
(PPRV) was currently divided into lineages I-IV and only one vaccine
strain N75 belongs to type II, its epidemic strains in China all belong
to lineage IV. As to achieve this goal, we developed an SYBR Green I
real-time RT-qPCR method for rapid detection and differentiation of PPRV
lineage II and IV by analyzing different melting curve analyses. Primers
targeting the L gene were highly specific, as evidenced by the negative
amplification of closely related viruses, such as Orf virus, goat
poxvirus, and Foot-and-mouth disease virus. The sensitivity of the assay
was assessed based on plasmid DNA and the detection limit achieved was
10 copies of PPRV-II and PPRV-IV respectively. As the method has high
sensitivity, specificity, and reproducibility, which will be significant
in effectively controlling the occurrence and transmission of PPRV.
Cluster Analysis of Allergic Poly-Sensitizations in Urban Adults with Asthma
Authors: Patchett Brian J. , Nriagu Bede N. , Mavraj Granit , Patel Ruchi R. , MacLellan Christopher , Thakur Tushar , Schulman Edward 
Published: January 2024

Introduction: While reliable in vitro testing for sensitivity to
common aeroallergens has been available for decades, if and how asthma
might be predictably expressed in people matched for comparable multiple
sensitizations is unknown. Objective: Our aim is to develop an
understanding of these relations, which are known as allergic
poly-sensitizations (APS) using a machine learning approach. We
performed an audit of adult urban patients with moderate to severe
asthma who presented to an urban outpatient pulmonary clinic. Methods:
We constructed a database of sensitizations to the 25 aeroallergens in
the zone 1 ImmunoCAP® assay. We used the Scikit-Learn® machine learning
library to perform model-based clustering to identify APS clusters.
Subsequently, clusters were compared for differences in clinical markers
of allergic asthma. Results: The database consisted of 509 patients.
Mixture modeling identified ten clusters of increasing APS of varying
size (n = 1 to 339). There were significant increases in mean serum
immunoglobulin E (p<.001), peripheral blood eosinophil count
(p<.001), and D (p=.02) with increasing
APS. There was a significant decline in mean age at presentation
(p<.001), FEV /FVC (p=.01), and FEF
(p=.002), but not FEV (p=.29),
nor RV/TLC (p=.14) with increasing APS by simple linear regression.
Finally, we identified two apparent divergent paths for the poly-atopic
march, one driven by perennial allergens and the other by seasonal
allergens. Conclusion: We provide the framework for a novel machine
learning understanding and approach to the classification of APS and its
heretofore under-appreciated potential influences on asthma cluster
analyses. To our knowledge, this represents the first attempt to
identify poly-sensitization patterns that have clinical implications.
Association Between Obesity and Surgical Outcomes in patients undergoing minimally invasive Hysterectomy
Authors: Jalloul Randa , Dziadek Olivia , Ward Clara , Bartal Michal 
Published: January 2024

Objective: To investigate morbidity associated with minimal invasive
hysterectomy in obese women. Design: This is a retrospective cohort
study using the National Surgical Quality Improvement Project database
from 2014 to 2017. Individuals that underwent a laparoscopic, robotic or
vaginal hysterectomy were included in the study. Our primary outcome was
the composite morbidity (including surgical site infection, sepsis,
pulmonary, thromboembolic, cardiac and renal complications, and death).
Our secondary outcomes included length of hospital stay, readmission,
reoperation, and other surgical complications. A multivariable logistic
regression was performed adjusting for age, race, American society of
anesthesiology classification (ASA), smoking, surgical approach and
operation time. Setting: Hospitals participating in the National
Surgical Quality Improvement Project database. Patients or
Participants: Patients undergoing minimally invasive hysterectomy for
benign disease. Measurements and Main Results: 39,368 individuals
underwent hysterectomies; 18,767 (47.8%) were obese. Class II obesity
or more was associated with increased risk for the primary outcome
compared to nonobese women. The difference in the primary outcome
primarily was driven by an increased risk of superficial site infection.
Class III obesity was associated with increased risk for length of stay.
There was no difference in the rate of ureteral/bladder/bowel injury,
urinary tract infection, blood transfusion, readmission, surgical site
closure or reoperation between obese and nonobese women. Conclusion: The
rate of surgical morbidity in obese women undergoing minimally invasive
hysterectomy remains higher. It is driven by surgical site infection.
Future interventions such as preoperative optimization as well as
specific wound care interventions in obese patients should be emphasized