bluuebunny/crossref_metadata_2025_split huggingface dataset:
Response of anchor investors to pre-IPO earnings management: evidence from an emerging market
Authors: Narang Sahil , Pradhan Rudra P. 
Published: December 2023

PurposeThis study aims to examine the reaction of anchor investors (AIs) to pre-IPO earnings management (EM). The authors use the unique detailed bid data from the Indian anchor experiment. The authors also study the reputed AIs’ EM detection ability and pricing behavior in response to pre-IPO EM.Design/methodology/approachThe authors use unique AI bid data for 169 Indian IPO firms. Utilizing the logistic regression and Tobit regression models with industry and year-fixed effects, the authors examine the relationship between various measures of AI participation and proxies of short-term and long-term discretionary accruals.FindingsThe authors document that pre-IPO EM is positively associated with the likelihood of anchor backing but negatively related to the likelihood of reputed anchor backing. The findings indicate that AIs are misled by pre-IPO EM, but reputed AIs are not. The authors also observe that reputed AIs, compared to the non-reputed, pay less than the upper band with increasing EM. The findings are robust to using various AI measures and EM proxies.Practical implicationsThe findings have significant implications for regulators in the implementation of AI concept in non-anchor markets and better implementation of policies in existing anchor settings. Findings can also be relevant for non-institutional investors in the IPO domain.Originality/valueThis is one of the few studies on institutional investors' IPO bidding behavior in response to pre-IPO EM. However, this is the first study to analyze AIs' IPO bidding behavior in response to pre-IPO EM.
Does digital transformation restrict the carbon emission intensity of enterprises? Evidence from listed manufacturing enterprises in China
Authors: Deng Fuming , Cai Lu , Ma Xiaolei 
Published: December 2023

AbstractDigitalization and greening are key themes in global development, the manufacturing industry, as a major sector of energy consumption and carbon emissions, is in urgent need of transformation to realize energy conservation and emission reduction, digital transformation provides an opportunity for its green development. However, whether digital transformation can restrain the carbon emission intensity (CEI) of enterprises is still controversial. Based on the data of China's A‐share manufacturing listed companies from 2013 to 2020, this paper uses fixed effect model and intermediary effect model to explore the relationship between digital transformation and enterprise CEI and the influence path. the results show that: (1) Digital transformation has significantly reduced the CEI of manufacturing enterprises. (2) Mechanism analysis indicates that green technological innovation and resource allocation efficiency play a chain mediating role in this relationship. (3) Heterogeneity analysis shows that the carbon emission reduction effect of digital transformation is more significant when enterprises belong to an energy‐intensive manufacturing industry or face strong environmental regulations and industry competition. The analysis of this paper not only deepens enterprises' understanding of digital transformation and green development but also provides a policy basis for China to advocate the coordinated development of the digital economy and green economy.
IgG4‐related retroperitoneal fibrosis induced by nivolumab and ipilimumab in a patient with non‐small cell lung cancer: A case report
Authors: Nishimura Masashi , Kimizuka Yoshifumi , Ogawa Takunori , Tsuchiya Motohiro , Kato Yoshiki , Matsukida Akira , Igarashi Shunya , Ito Koki , Serizawa Yusuke , Tanigaki Tomomi , Fujikura Yuji , Katsurada Yuka , Ogata Sho , Kawana Akihiko 
Published: December 2023

AbstractIgG4‐related diseases are adverse events that occur after receiving treatment with immune checkpoint inhibitors (ICI). This study reports the first case of IgG4‐related retroperitoneal fibrosis after the administration of chemotherapy with nivolumab and ipilimumab (NI therapy). An 80‐year‐old man developed lower abdominal pain eight months after NI therapy was initiated. Although the primary lesion maintained its reduced size on computed tomography, there was an increase in the soft tissue shadows intensity around the abdominal aorta, bladder, and seminal vesicles, suggesting retroperitoneal fibrosis. Blood tests showed elevated IgG4 levels. Computed tomography‐guided biopsy of the retroperitoneum showed B cell‐dominant lymphocyte infiltration consistent with IgG4‐related retroperitoneal fibrosis and characteristic CD8‐positive lymphocyte infiltration, suggestive of the involvement of cytotoxic T cells. Based on the clinical, imaging, and pathological findings, the patient was diagnosed with IgG4‐related retroperitoneal fibrosis due to ICI. Immunotherapy discontinuation alone did not result in improvement; therefore, steroid therapy was initiated. In clinical practice, IgG4‐related retroperitoneal fibrosis can occur as an immune‐related adverse event when administering anti‐PD‐1 and anti‐CTLA‐4 antibodies for cancer immunotherapy. Early steroid therapy could be effective in controlling this immune‐related adverse event.
Women's fear of childbirth during pregnancy: A concept analysis
Authors: Souto Sandra P. , Prata Ana Paula , Albuquerque Rosemeire S. , Caldeira Sílvia 
Published: December 2023

AbstractPurposeTo map and analyze the concept of women's fear of childbirth (FOC) during pregnancy and to develop a new nursing diagnosis (ND).MethodsConcept analysis based on Walker and Avant's methodology. An integrative literature search was conducted in Scopus, Web of Science, and CINAHL Complete databases, including peer‐reviewed articles published in English from January 1981 to October 2022.FindingsThirty‐one studies were included in the review. Women's FOC during pregnancy comprises three central categories: attributes, antecedents, and consequences. Nine main characteristics (attributes) are related to one or more of eight prior conditions (antecedents) that have the potential to exert negative or favorable impacts (consequences), depending on whether coping strategies have been a part of a fearful woman's pregnancy. These elements and relationships among them should be viewed as dynamic.ConclusionsWomen's FOC during pregnancy is a subjective, multidimensional, and dynamic concept that benefits prenatal care responses. A conceptual matrix on prenatal care will consider the factors underlying women's FOC and their potential mechanisms, how fearful pregnant women respond, the aspects that shape FOC, and how it influences outcomes when supporting pregnant women with FOC. Therefore, the study findings can be used to inform ways of identifying fearful women or as a basis for interventions to manage fears and enhance the confidence of pregnant women for childbirth.Implications for nursing practiceThe results of this study help nurses, OB nursing practitioners, nurse–midwives, and midwives to identify the condition of women's FOC during pregnancy and guide nursing therapeutic interventions to decrease the negative effects on women's health and well‐being. Therefore, there are valuable reasons to propose using “fear of childbirth” as a ND in the class “coping responses” within domain coping/stress tolerance, contributing to refining the NANDA‐I taxonomy.
Dietary index based on the Food Standards Agency nutrient profiling system and risk of Crohn's disease and ulcerative colitis
Authors: Meyer Antoine , Dong Catherine , Chan Simon S. M. , Touvier Mathilde , Julia Chantal , Huybrechts Inge , Nicolas Geneviève , Oldenburg Bas , Heath Alicia K. , Tong Tammy Y. N. , Key Timothy J. , Tjønneland Anne , Kyrø Cecilie , Kaaks Rudolf , Katzke Verena A. , Bergman Manuela M. , Palli Domenico , Masala Giovanna , Tumino Rosario , Sacerdote Carlotta , Colorado‐Yohar Sandra M. , Sánchez Maria‐Jose , Guevara Marcela , Grip Olof , Holmgren Johanna , Cross Amanda , Karling Pontus , Hultdin Johan , Murphy Neil , Deschasaux‐Tanguy Mélanie , Hercberg Serge , Galan Pilar , Mahamat‐Saleh Yahya , Amiot Aurélien , Gunter Marc J. , Boutron‐Ruault Marie‐Christine , Carbonnel Franck 
Published: December 2023

SummaryBackgroundNutri‐score is now widely available in food packages in Europe.AimTo study the overall nutritional quality of the diet in relation to risks of Crohn's disease (CD) and ulcerative colitis (UC), in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohortMethodsWe collected dietary data at baseline from validated food frequency questionnaires. We used a dietary index based on the UK Food Standards Agency modified nutrient profiling system (FSAm‐NPS‐DI) underlying the Nutri‐Score label, to measure the nutritional quality of the diet. We estimated the association between FSAm‐NPS‐DI score, and CD and UC risks using Cox models stratified by centre, sex and age; and adjusted for smoking status, BMI, physical activity, energy intake, educational level and alcohol intake.ResultsWe included 394,255 participants (68.1% women; mean age at recruitment 52.1 years). After a mean follow‐up of 13.6 years, there were 184 incident cases of CD and 459 incident cases of UC. Risk of CD was higher in those with a lower nutritional quality, that is higher FSAm‐NPS‐DI Score (fourth vs. first quartile: aHR: 2.04, 95% CI: 1.24–3.36; p‐trend: <0.01). Among items of the FSAm‐NPS‐DI Score, low intakes of dietary fibre and fruits/vegetables/legumes/nuts were associated with higher risk of CD. Nutritional quality was not associated with risk of UC (fourth vs. first quartile of the FSAm‐NPS‐DI Score: aHR: 0.91, 95% CI: 0.69–1.21; p‐trend: 0.76).ConclusionsA diet with low nutritional quality as measured by the FSAm‐NPS‐DI Score is associated with a higher risk of CD but not UC.
Estimation of off‐farm temperatures and temperature‐humidity index from meteorological observation records
Authors: Satoh Masahiro , Fukuzawa Yo , Ogawa Shinichiro , Okamura Toshihiro 
Published: December 2023

AbstractThe objective of this study was to devise an optimal method for estimating air temperatures outside pig farms to be able to evaluate the genetic performance of pigs. Using daily temperature data from Japan Meteorological Agency meteorological stations, we investigated the optimal number of observation weather stations (number of records), and methods of estimating outside temperature when temperature records are missing. We also considered the possibility of using relative humidity data. Our results showed that it is possible to use records from the three nearest weather stations to estimate off‐farm ambient temperatures. We also concluded that estimates of outside temperatures when records are missing can be made by using data from at least one weather station that holds a full set of data. The correlation coefficients between the true THI (temperature‐humidity index) and the estimated THI and the average daily temperature were almost the same, indicating that the daily average temperature can be used instead of estimated THI.
Why do college students engage in in‐class media multitasking behaviours? A social learning perspective
Authors: Yin Chunxiao , Li Lirui , Yu Liang 
Published: December 2023

AbstractPeople in modern society are media multitaskers due to portable devices and omnipresent wireless networks, and college students are no exception. Previous studies have indicated that students' media multitasking behaviours in class harm their academic performances, and understanding the reasons for college students' engagement in such behaviour is meaningful. However, the literature takes media multitasking behaviour as an audience behaviour, which ignores the interaction between students and their surroundings. This study fills this gap by emphasizing the role of the social learning process. A survey was conducted in a public and comprehensive university in western China, and a total of 457 valid respondents were obtained. The results from PLS‐SEM revealed that college students' in‐class media multitasking behaviours were influenced by both observational learning (ie, imitating others) and reinforcement learning (ie, in‐class interventions), and this learning process was shaped by students' media multitasking self‐efficacy and self‐management of learning. These findings contribute to the current literature by providing a relatively new perspective for understanding college students' in‐class media multitasking behaviours, and suggestions about how to deal with such behaviours are also provided.
Practitioner notesWhat is already known about this topic

In‐class media multitasking behaviours (ICMMBs) damage college students' academic performance.
College students' ICMMBs are affected by individual factors, such as internet addiction and sensation seeking.
Social learning theory is widely adopted as a general theoretical background to explain those behaviours of which possible consequences are easily observed no matter from others or from individuals themselves.
What this paper adds

This work enriches the media multitasking literature by investigating the predictors of ICMMBs from a relatively new perspective, that is, the social learning perspective.
This work also contributes to the literature on media multitasking by examining how the social learning process of college students' ICMMBs differs across students.
This work extends the application scope of social learning theory to the context of college students' ICMMBs.
Implications for practice and/or policy.

The role of imitating others proves the importance of the learning atmosphere in classrooms, so teachers or lecturers should pay special attention to build a learning atmosphere away from ICMMBs.
Some in‐class interventions should be established, especially the formal policy of schools to require students to hand in their smartphones or other media before class and students' own mindfulness of such behaviour.
Teachers or lecturers should take actions to lower the academic performance expectations of students with higher media multitasking self‐efficacy (MMSE) because students with higher MMSE often overestimate their capabilities to have good performance when conducting other tasks simultaneously.
Treatment and follow‐up of children with chronic myeloid leukaemia in chronic phase (CML‐CP) in the tyrosine kinase inhibitor (TKI) era—Two decades of experience from the Tata Memorial Hospital paediatric CML (pCML) cohort
Authors: Roy Moulik Nirmalya , Keerthivasagam Swaminathan , Pandey Ankita , Agiwale Jayesh , Hegde Kriti , Chatterjee Gaurav , Dhamne Chetan , Prasad Maya , Chichra Akanksha , Srinivasan Shyam , Mohanty Purvi , Jain Hemani , Shetty Dhanlaxmi , Tembhare Prashant , Patkar Nikhil , Narula Gaurav , Subramanian Papagudi G. , Banavali Shripad 
Published: December 2023

SummaryTyrosine kinase inhibitors (TKIs) have drastically improved the outcomes of pCML (paediatric CML) but data on long‐term off‐target toxicities of TKIs in children are scarce. In this single‐centre, retrospective cum prospective study of pCML in chronic phase, we report our experience of treating 173 children with imatinib and following them for long‐term toxicities. Mean (SD) time to attain CHR, CCyR and MMR were 3.05 (2.1), 10.6 (8.4) and 43.4 (31.8) months respectively. DMR was not attained in 59 (34%) patients at last follow‐up. Ten patients were switched to second‐generation TKIs (2G‐TKIs; nilotinib = 1/dasatinib = 9) due to poor/loss in response, of which seven had kinase domain mutations. Three patients progressed to the blastic phase. At a median follow‐up of 84 (3–261) months, the 5‐year EFS and OS for the entire cohort were 96.9% (95% CI: 93.4–100) and 98.7% (95% CI: 96.9–100) respectively. Screening for long‐term toxicities revealed low bone density and hypovitaminosis D in 70% and 80% respectively. Other late effects included short stature (27%), delayed puberty (15%), poor sperm quality (43%) and miscellaneous endocrinopathies (8%). Children younger than 5 years at diagnosis were more susceptible to growth and endocrine toxicities (p = 0.009). Regular monitoring for long‐term toxicities, timely intervention and trial of discontinuation whenever feasible are likely to improve the long‐term outlook of pCML.
Impact of lymphovascular invasion on survival in surgically treated upper tract urothelial carcinoma: a nationwide analysis
Authors: Cirulli Giuseppe Ottone , Corsi Nicholas , Rakic Ivan , Stephens Alex , Chiarelli Giuseppe , Finati Marco , Davis Matthew , Tinsley Shane , Sood Akshay , Buffi Nicolò , Lughezzani Giovanni , Carrieri Giuseppe , Salonia Andrea , Briganti Alberto , Montorsi Francesco , Rogers Craig , Abdollah Firas 
Published: December 2023

ObjectivesTo assess the prognostic ability of lymphovascular invasion (LVI) in upper tract urothelial carcinoma (UTUC) as a predictor of overall survival (OS) using a large North American cohort.Patients and MethodsOur cohort included 5940 patients with clinical M0 UTUC who underwent a radical nephroureterectomy (RNU), between 2010 and 2016, within the National Cancer Database. The main variable of interest was LVI status, and its interaction with pathological nodal (pN) status. Kaplan–Meier curves were used to depict the OS also stratifying patients on LVI status. Cox regression analysis tested the impact of LVI status on OS after accounting for the available covariates.ResultsThe median (interquartile range [IQR]) age at diagnosis was 71 (63–78) years and most patients had pathological T1 stage disease (48.6%). Nodal status was pN0, pN1 and pNx in 45.8%, 6.3% and 47.9%, respectively. Overall, 22.1% had LVI. The median (IQR) follow‐up time was 32.6 (16.0–53.3) months. At the 5‐year postoperative follow‐up, the estimated OS rate was 28% in patients with LVI vs 66% in those without LVI (P < 0.001). When patients were stratified based on nodal status those rates were 32% vs 68% in pN0 patients (P < 0.001), 23% vs 30% in pN1 patients (P = 0.8), and 28% vs 65% in pNx patients (P < 0.001). On multivariable analysis, the presence of LVI was associated with less favourable OS (hazard ratio 1.79, 95% confidence interval 1.60–1.99; P < 0.001).ConclusionOur study assessed the impact of LVI on OS in patients with UTUC in a large North American nationwide cohort. Our series, as the largest to date, indicate that LVI is associated with less favourable survival outcomes in patients with UTUC after RNU, and this variable could be used in counselling patients about their prognosis and might be a useful tool for future trials to risk‐stratify patients.
Occupational performance and participation in children with developmental coordination disorders before and during Covid‐19
Authors: Kolit Zeynep , Temizkan Ege , Kara Özgün Kaya , Kara Koray , Şahin Sedef 
Published: December 2023

AbstractIntroductionDevelopmental coordination disorder (DCD) is a neurodevelopmental disorder that affects children's occupational performance and participation. It is known that the Covid pandemic has adversely affected the whole world in many areas. We aim to investigate the occupational performance and participation of children with DCD before and during the COVID‐19.MethodsSixty‐five children aged 5–12 years included in the study were assessed by the Canadian Measure of Occupational Performance and the Participation and Environment Measure for Children and Youth.ResultsStatistically significant differences were detected in occupational performance and satisfaction scores (p < 0.01). Additionally, except for ‘involvement in the home environment’ (p > 0.05), there were statistically significant differences in all other areas of participation (p < 0.01).ConclusionThe occupational performance and participation of children with DCD are impacted during COVID‐19. In addition, it is seen that the desire of families to change regarding participation has increased due to COVID‐19. It would be beneficial to include strategies to improve these areas in the rehabilitation processes.
Can angiotropism and lymphovascular invasion refine the current cutaneous melanoma staging system?
Authors: Namubiru Patricia , Dalleywater William , Lashin Shaimaa , Elsheikh Somaia 
Published: December 2023

AbstractBackgroundSeveral prognostic factors for primary cutaneous melanoma (PCM) have been identified, and these predict metastasis and survival, to a certain extent. We sought to determine the frequency of angiotropism (AT) and lymphovascular invasion (LVI) in PCM and the relationship between AT, LVI, and other clinicopathological parameters and patient's prognosis.MethodsThis study included 538 cases of PCM diagnosed between 2003 and 2016. It comprised 246 females and 292 males whose clinicopathological variables were evaluated with respect to LVI and AT using univariate and multivariate analyses. Overall survival (OS) was assessed by Kaplan–Meier (KM) analysis and Cox regression multivariate analysis.ResultsAT occurred more frequently than LVI. Ulceration, mitotic rate, and Breslow thickness were found to be highly associated with both LVI and AT (p < 0.01). All LVI+ cases had AT, with a significant positive correlation (p < 0.01). Both AT and LVI predicted lymph node (LN) metastasis (odds ratio [OR] = 1.47, 1.12, respectively). Multivariate analysis showed LN metastasis, Breslow thickness, LVI, and AT as predictors of OS. LVI and AT independently predicted adverse OS by Cox regression analysis (hazard ratio [HR] = 1.66, 1.49, respectively) and with KM survival analysis.ConclusionAT is a marker for angiotropic extravascular migratory tumor spread (angiotropic EVMM), and LVI is a marker for intra‐lymphovascular tumor spread. Both predict poor prognosis. Given its ease of detection, AT could be adopted as a histologpathological feature in the routine assessment of primary cutaneous malignant melanoma cases.
Neural complexity and the spectral slope characterise auditory processing in wakefulness and sleep
Authors: Alnes Sigurd L. , Bächlin Lea Z. M. , Schindler Kaspar , Tzovara Athina 
Published: December 2023

AbstractAuditory processing and the complexity of neural activity can both indicate residual consciousness levels and differentiate states of arousal. However, how measures of neural signal complexity manifest in neural activity following environmental stimulation and, more generally, how the electrophysiological characteristics of auditory responses change in states of reduced consciousness remain under‐explored. Here, we tested the hypothesis that measures of neural complexity and the spectral slope would discriminate stages of sleep and wakefulness not only in baseline electroencephalography (EEG) activity but also in EEG signals following auditory stimulation. High‐density EEG was recorded in 21 participants to determine the spatial relationship between these measures and between EEG recorded pre‐ and post‐auditory stimulation. Results showed that the complexity and the spectral slope in the 2–20 Hz range discriminated between sleep stages and had a high correlation in sleep. In wakefulness, complexity was strongly correlated to the 20–40 Hz spectral slope. Auditory stimulation resulted in reduced complexity in sleep compared to the pre‐stimulation EEG activity and modulated the spectral slope in wakefulness. These findings confirm our hypothesis that electrophysiological markers of arousal are sensitive to sleep/wake states in EEG activity during baseline and following auditory stimulation. Our results have direct applications to studies using auditory stimulation to probe neural functions in states of reduced consciousness.