bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bentuk Pengungkapan Citraan pada Aspek Kejiwaan dalam Sajak Penyair Jambi Dimas Arika Miharja
Authors: Sumiharti Sumiharti , Amral Sainil 
Published: October 2023

This research is included in the type of descriptive research with a content analysis approach to documents in the form of poetry literary works. The purpose of this study is to describe the type of image revealing psychological aspects contained in the poems of Jambi poet Dimas Arka Mihardja. The primary data in this study are words or sentences in the form of expressions contained in poems by Jambi poet Dimas Arka Mihardja which are related to the image of revealing psychological aspects. While the source of data in this study is the Anthology of Jambi Poetry Poems by Dimas Arka Mihardja. Research data were collected using documentation study techniques. The research data were analyzed using document analysis techniques that rely on rhyme discourse containing psychiatric aspects. From the results of the study, it was found that the poems of Jambi poet Dimas Arka Mihardja contained many forms of imaging revealing psychological aspects in the form of visual images, auditory images, olfactory images, taste images and motion images. Psychiatric aspects found include depression, obsession, irritation, fear, frustration, hope, attention, and anxiety.
Extracción de aceites esenciales de dos especies forestales y dos especies arbustivas para la determinación de sus propiedades en condiciones de laboratorio
Authors: Valle Logroño Klever Xavier , Paredes Herrera Marco Marcel , Benavides Enríquez Celso Vladimir , Basantes Vaca Carmen Viviana 
Published: October 2023

Introducción: la filosofía de la ingeniería forestal no debería estar únicamente enfocada a planificar y ejecutar sistemas de explotación forestal, sino más bien dar énfasis como alternativa a la conservación ambiental a la investigación de la extracción de aceites esenciales que en son útiles en la industria, medicina, fitoterapia, perfumería, etc. Objetivos: El objetivo de esta investigación fue la obtención de aceites esenciales de las especies forestales de Eucalipto, Molle , edemas especies arbustivas como el Romero y Cedrón, la determinación de su composición , Utilizando la técnica de estracción de aceites de arrastre a vapor se obtuvo los siguientes Resultados: El rendimiento del Eucalipto fue de 12%; Molle 7%; Cedrón 2% ; Romero 0,60%; Mediante la técnica de cromatografía fina se determinó que el Eucalipto presenta 0.39% Cineol; 0.50% Pineno, 0.65 % Terpineol; El Molle presenta 0.23% Terpineol, 0.38% Felandreno, 0.50% Metil Pentanol; El Romero presenta 0.45% Pineno, 0.60% de Cineol, 0.70% Bromeol, 0.82% Alcanfor; El Cedrón presenta 0.48% Citral, 0.55% de Berona. Conclusiones: Los aceites esenciales son compuestos fenólicos y aromáticos volatiles, poseen diferente grado de refracción, peso específico, concentración y pureza, están constituidos por moléculas orgánicas, presentando diferente estructura y disposición especial. Área de estudio general: Aromatología. Área de estudio Especifico: Aromaterapia.
COMPARATIVE ASSESSMENT OF HARDNESS OF TWO NANO-HYBRID RESIN-BASED DENTAL COMPOSITES
Authors: Amin Nayab , Siddiqui Usama , Ammar Sahibzada , Ejaz Munazzah 
Published: October 2023

Objectives: To compare the hardness of two nano-hybrid resin-based dental composites.
Materials and Methods: Two nano-hybrid composites i.e., Nexcomp by Meta Biomed, Korea, and Tetaric N Ceram by Ivoclar Vivadent, AG, Liechtenstein were selected, and hardness was evaluated according to ASTM E384-11e. T-test was used to statistically analyze the data.
Results: The mean hardness value (VHN) of Tetaric N Ceram (78.4±3.14) was high when compared with Nexcomp (50±4.12). The statistical analysis showed a signifi cant diff erence with p-value of 0.00.
Conclusion: Both composites had adequate hardness values and dental practitioners may select the material subject to the clinical situation and patient’s aff ordability.
EVALUATION OF OUTCOME OF FULL PULPOTOMY IN MATURE PERMANENT MOLARS WITH SYMPTOMATIC IRREVERSIBLE PULPITIS
Authors: Ali Ahsan , Maqbool Hassan , Khan Ghulam Ishaq , Abrar Faisal , Ali Shah Fawad , Zeb Jan Mashal 
Published: October 2023

Objectives: To assess the outcome of full pulpotomy in patients with symptomatic irreversible pulpitis.
Materials and Methods: This observational study was done at the Endodontics Department, Rehman College of Dentistry, Peshawar from April 2022 to April 2023. Eighty-four patients within the age range of 18-50 years with painful vital permanent molar were selected using purposive sampling. Full Pulpotomy procedure was performed. Treatment was completed in two visits. In the first visit, after taking an informed consent the tooth was anesthetized, and full pulpotomy was done. A cotton pellet soaked in 3% sodium hypochlorite (NaOCL) was used to achieve hemostasis. After achieving hemostasis, a 2-4mm of mineral trioxide aggregate was used to seal the root stumps and restored with glass ionomer cement. In the second visit, the glass ionomer cement was removed, and tooth was permanently restored using composite fi lling material. Outcome was evaluated in terms of pain and periapical changes at one week and six month post-operatively. The outcome was considered successful in case of no or mild pain and no periapical changes post-operatively. Data was entered using SPSS version 26.0.
Results: In the present study 46.4% males and 53.6% females were included. The mean age was 34.04±10.524. Follow-up showed 95.2% success after one week and 89.3% after six months. No significant association of the outcome with age, gender and tooth type was found (p value > 0.05).
Conclusion: Full pulpotomy was successful in patients with symptomatic irreversible pulpitis.
Analisis Selisih Biaya Antara Tarif riil Rumah Sakit Dengan Tarif Ina-Cbgâ€™s Pada Kasus Sectio Caesarean Di Rumah Sakit Panti Nugroho
Authors: Pradnyantara I Gusti Agung Ngurah Putra 
Published: October 2023

AbstrakLatar Belakang :Angka operasi caesar terus meningkat di setiap negara, WHO merekomendasikan Caesarean Section Rate (CSR) yang ideal bagi suatu negara berkisar 10% sampai 15%. Rumah Sakit Panti Nugroho merupakan rumah sakit rujukan Pelayanan Obstetri Neonatal Emergency Dasar (PONED) yang bekerja sama dengan Jaminan Kesehatan Nasional yang menerapkan sistem INA-CBGâ€™s. Dalam penerapan sistem INA-CBGâ€™s sering terjadi permasalahan dalam pembiayaanya. Hal yang sering terjadi adalah besarnya tarif rumah sakit pada prosedur Sectio Caesarea melebihi klaim INA-CBGâ€™s. Tujuan :Penelitian ini bertujuan untuk mengetahui selisih antara tarif rumah sakit dengan klaim INA-CBGâ€™s di RS Panti Nugroho. Metode penelitian : penelitian ini adalah Â penelitian deskriptif dengan pendekatan kualitatif, data diambil secara retrospektif dari data klaim peserta JKN pasien Sectio Caesarea tahun 2020 di RS Panti Nugroho sebanyak 89 sampel data menggunakan total sampel. Perhitungan data untuk mengetahui selisih dilakukan dengan cara mengurangkan tarif rumah sakit dengan tarif INA-CBGâ€™s.Hasil penelitian: menunjukkan selisih antara tarif rumah sakit dengan tarif INA-CBGâ€™s pada pasien Sectio Caesarea di RS Panti Nugroho adalah selisih negative nilai, selisih minimumnya sebesar Rp 834.699,00 dan selisih maksimalnya sebesar Rp 7.517.699,00 dengan nilai rata-rata selisihnya sebesar Rp3.036.855,37. nilai persentase selisih minimal sebesar 13,59% dan persentase selisih maksimalnya sebesar 58,62% dengan nilai rata-rata persentase selisihnya sebesar 36,66%Kesimpulan :dapat disimpulkan bahwa nilai rata-rata pada tarif RS dan tarif INACBG tidak sama, dimana tarif RS lebih besar dari pada tarif INACBG Diharapkan tim BPJS melakukan analisa tarif setiap bulannya untuk bahan evaluasi manajemen rumah sakit dalam pengendalian tarif dan melakukan evaluasi penghitungan unit cost pada layanan persalinan dengan pertolongan section caesarean yang mengalami selisih tarifÂ Kata Kunci: Selisih tarif, Sectio Cesarea, Tarif Rumah Sakit.
«Муравйовщина»: російська військова диктатура в Одесі (лютий-березень 1918 р.) у листівках і наказах з колекції бібліотечного фонду Державного архіву Одеської області
Authors: Савченко Віктор 
Published: October 2023

Стаття присвячена аналізу одеського епізоду російської агресії в Україні, який увійшов в історію під назвою «муравйовщина» (лютий-березень 1918 р.). У той час російський колоніалізм проявився у вигляді вторгнення на терени незалежної України й окупації значної частини УНР. М. Муравйов був призначений російським комуністичним урядом командуючим військом, що окупувала Україну, а згодом, Командувачем фронтом, який діяв проти «румунської олігархії». Цей фронт проходив на Одещині, а своїм «центром» М. Муравйов призначив Одесу, де він вирішив встановити особисту військову диктатуру. Фактично відсторонивши від прийняття владних рішень одеський Совєт, одеську Раду Народних комісарів, Румчерод та арештувавши представників міського самоврядування, він встановив військове «осадне» положення у місті.
Три тижні «муравйовщини» в Одесі висвітлили особливості колоніальної залежності від РСФРР: грабунки та здирництво з боку «завойовників», злочини проти особистості стали буденною справою. Диктатура будувалася завдяки знищенню місцевого самоврядування, свободи слова, свободи зборів, української ідентичності. «Червона» диктатура трималася на більшовиках, що були «відряджені» до Одеси з Петрограду, солдат армії Муравйова з РСФРР, та на матросах Чорноморського флоту. Брутальна поведінка військової хунти Муравйова привела до масових протестів, що проявлялися у бойкоті мобілізації і бойкоті підтримки армії та військової диктатури, протестах і маніфестаціях одеситів.
Hubungan Pola Hidup Terhadap Kadar Gula Darah Penderita Diabetes Mellitus Tipe 2
Authors: Rini Syarifah , Manto Onieqie Ayu Dhea , Irawan Angga 
Published: October 2023

Latar Belakang: Diabetes Melitus merupakan suatu kelompok penyakit metabolik dengan karakteristik hiperglikemia (tinggi kadar gula darah) yang terjadi akibat kelainan pengeluaran insulin, kerja suatu insulin ataupun keduanya. DM tipe 2 Harus selalu memperhatikan pola hidup agar tetap sehat atau dengan cara selalu memperhatikan 5 pilar pengelolaan diabetes mellitus yaitu makanan, obat-obatan, olahraga, kontrol glikemik, perawatan kaki dan yang paling penting yaitu pola makan dan diet agar mencegah terjadinya peningkatan kadar gula darah dan menghindari terjadinya komplikasi karena banyak masyarakat yang masih tidak memperhatikan pola makan dan pola diet.
Tujuan: Untuk mengetahui hubungan antara pola hidup terhadap kadar gula darah penderita DM tipe 2 di UPT Puskesmas Terminal Banjarmasin
Metode: Penelitian ini menggunakan metode kuantitatif dan menggunakan pendekatan studi cross sectional. Jumlah sampel sebanyak 73 orang dengan teknik purposive sampling
Hasil: Hasil uji korelasi Chi Square dengan Î± = 0,05. Dari hasil uji statistik Chi Square didapatkan Nilai signifikan 0.441 > 0,05 menunjukkan tidak ada hubungan antara pola hidup terhadap kadar gula darah penderita DM Tipe 2.
Kesimpulan: Meningkatnya kadar gula darah tidak hanya dipengaruhi oleh pola hidup tetapi juga dipengaruhi oleh faktor lain seperti pola makan, diet, merokok, perawatan kaki dan perawatan diri diabetes
Kata kunci: diabetes melitus, kadar gula darah, pola hidup
FAKTOR FAKTOR YANG MEMPENGARUHI KEPATUHAN KUNJUNGAN LANSIA KE POSYANDU LANSIA DI DESA RANTAU PANJANG HULU KECAMATAN KUSAN HILIR KABUPATEN TANAH BUMBU TAHUN 2020
Authors: Putra Farhandika , Hikmah Indah Nurul 
Published: October 2023

Latar Belakang: Posyandu lansia adalah pos pelayanan terpadu untuk masyarakat lansia di wilayah tertentu yang sudah disepakati, yang digerakkan oleh masyarakat untuk mendapatkan pelayanan kesehatan. Tujuan: Tujuan penelitian ini untuk mengetahui faktor-faktor yang mempengaruhi kepatuhan kunjungan lansia ke posyandu lansia. Metode: Jenis penelitian ini adalah survei analitik dengan pendekatan cross sectional. Sampel dalam penelitian ini 32 lansia yang terdaftar di posyandu lansia teknik sampling total sampling. Instrumen yang digunakan berupa kuesioner dan KMS. Hasil: Dari hasil penelitian didapatkan bahwa variabel independen yang berpengaruh dengan kepatuhan kunjungan lansia adalah tingkat pendidikan lansia (p value = 0,000), tingkat pengetahuan lansia (p value = 0,08), sikap lansia (p value = 0,08), Sosial Ekonomi (p value = 0,000), variabel independen paling berpengaruh yaitu faktor pendidikan dan sosial ekonomi dengan (p value = 0,000). Kesimpulan: Kesimpulan dari penelitian ini adalah terdapat faktor yang paling mempengaruhi kepatuhan kunjungan lansia ke posyandu lansia adalah faktor pendidikan dan sosial ekonomi. Saran dari penelitian ini diharapkan kepada kader dan petugas kesehatan untuk dapat meningkatkan kualitas pelayanan dengan memberi penyuluhan lansia dan keluarganya mengenai pentingnya posyandu lansia
Functional contacts for activation of urease from Helicobacter pylori: an integrated approach using evolutionary couplings, in-cell enzymatic assays, and computational docking
Authors: Carosella Noemi , Brock Kelly P. , Zambelli Barbara , Musiani Francesco , Sander Chris , Ciurli Stefano 
Published: October 2023

Introduction: Urease is an enzyme exploited by many virulent bacteria and fungi to infect the host and exert their virulence. The Gram-negative bacterium Helicobacter pylori relies on the activity of urease to infect the highly acidic human stomach. The activity of urease depends on the presence of a catalytic site containing two Ni(II) ions. In vivo, urease is initially synthesized as an inactive apo-enzyme and requires a post-translational activation process that involves the incorporation of the metal ions into its buried active site. In H. pylori, as well as in other bacteria, this activation process is mediated by four accessory proteins, named UreD, UreF, UreG, and UreE. Targeting the interactions between urease chaperones could potentially inhibit the activation of urease through blocking the Ni(II) ions incorporation, providing a route for the development of antimicrobial strategies against ureolytic pathogens.Methods: In this paper, an evolutionary couplings (EC) approach was adopted to determine the interaction surface between urease and UreD, the first protein that binds the enzyme, preparing it for the subsequent activation steps. Site-directed mutagenesis and an in-cell assay were used to detect urease activity in recombinant bacteria expressing the mutated operon. The obtained data were used to drive a protein-protein docking computational approach.Results and Discussion: The EC prediction retrieved ten pairs of residues lying at the interface between UreD and the urease subunit UreB, likely involved in contacts essential to build the protein complex. These contacts were largely confirmed experimentally, leading to the obtainment of a model for the urease-UreD complex that agrees well with the recently reported experimental cryo-EM structure. This work represents a proof of concept for the calculation of reliable models of protein interaction surfaces in the absence of experimental structures of critical assemblies.
Bioprospecting for the soil-derived actinobacteria and bioactive secondary metabolites on the Western Qinghai-Tibet Plateau
Authors: Liu Lifang , Liu Yuyu , Liu Shaowei , Nikandrova Arina A. , Imamutdinova Arina N. , Lukianov Dmitrii A. , Osterman Ilya A. , Sergiev Petr V. , Zhang Benyin , Zhang Dejun , Li Feina , Sun Chenghang 
Published: October 2023

IntroductionThe increase in incidence of multidrug-resistant bacteria and the inadequacy of new antimicrobial drugs have led to a widespread outbreak of bacterial antimicrobial resistance. To discover new antibiotics, biodiversity, and novelty of culturable actinobacteria dwelled in soil of the Western Qinghai-Tibet Plateau were investigated. By integrating antibacterial assay with omics tools, Amycolatopsis sp. A133, a rare actinobacterial strain and its secondary metabolites were further studied.MethodCulture-dependent method was used to obtain actinobacterial strains from two soil samples collected from Ali region in Qinghai-Tibet Plateau. The cultural extractions of representative strains were assayed against “ESKAPE” pathogens by paper-disk diffusion method and the double fluorescent protein reporter “pDualrep2” system. An Amycolatopsis strain coded as A133 was prioritized and its secondary metabolites were further analyzed and annotated by omics tools including antiSMASH and GNPS (Global Natural Social Molecular Networking). The predicted rifamycin analogs produced by Amycolatopsis sp. A133 were isolated and identified by chromatographic separation, such as Sephadex LH-20 and HPLC, and spectral analysis, such as NMR and UPLC-HRESI-MS/MS, respectively.ResultsA total of 406 actinobacteria strains affiliated to 36 genera in 17 families of 9 orders were isolated. Out of 152 representative strains, 63 isolates exhibited antagonistic activity against at least one of the tested pathogens. Among them, 7 positive strains were identified by the “pDualrep2” system as either an inhibitor of protein translation or DNA biosynthesis. The cultural broth of Amycolatopsis sp. A133 exhibited a broader antimicrobial activity and can induce expression of TurboRFP. The secondary metabolites produced by strain A133 was annotated as rifamycins and zampanolides by antiSMASH and GNPS analysis. Five members of rifamycins, including rifamycin W, protorifamycin I, rifamycin W-M1, proansamycin B, and rifamycin S, were purified and identified. Rifamycin W-M1, was found as a new member of the naturally occurring rifamycin group of antibiotics.DiscussionAssisted by omics tools, the successful and highly efficient discovery of rifamycins, a group of clinically used antibiotics from actinobacteria in Ali area encouraged us to devote more energy to explore new antibiotics from the soils on the Western Tibetan Plateau.
Pandemic-specific coping, anxiety, and depression across multiple waves of COVID-19 in elite athletes with disabilities
Authors: Urbański Piotr K. , Tasiemski Tomasz , Brewer Britton W. 
Published: October 2023

ObjectivesCompetitive athletes have faced many of the same mental health challenges experienced by the general population during the COVID-19 pandemic. The purpose of the current study was to examine the extent to which pandemic-specific coping predicted anxiety and depression over and above general coping styles in elite athletes with disabilities across multiple waves of the COVID-19 pandemic.MethodsParticipants were 91 athletes (60 men and 31 women) in the Polish Paralympic Preparation Program before the 2020 Tokyo Summer Paralympic Games and 2022 Beijing Winter Paralympic Games. The Coping Inventory for Stressful Situations and an open-ended item asking participants to describe coping resources they had used to overcome stressful situations caused by the pandemic were administered in April 2021, and the Hospital Anxiety and Depression Scale was administered in April, July, and November of 2021.ResultsGeneral coping styles were not significantly associated with pandemic-specific coping, anxiety, or depression in the July and November 2021 assessments. Pandemic-specific coping was related prospectively to both anxiety and depression across the July and November 2021 assessments when controlling for age, gender, general coping styles, and April 2021 anxiety and depression, respectively.ConclusionThe findings suggest that elite athletes with disabilities may cope with pandemic-related stress differently from how they cope with stress in general and that pandemic-specific coping may be relevant to mental health outcomes during the COVID-19 pandemic. This information may be useful in the development of interventions to assist elite athletes with disabilities cope with pandemics and other atypical stressors.
Adherence to Pharmacotherapies After Heart Transplantation in Relation to Multimorbidity and Socioeconomic Position: A Nationwide Register-Based Study
Authors: Mols Rikke E. , Bakos István , Løgstrup Brian B , Horváth-Puhó Erzsébet , Gustafsson Finn , Eiskjær Hans 
Published: October 2023

No studies have examined the impact of multimorbidity and socioeconomic position (SEP) on adherence to the pharmacological therapies following heart transplantation (HTx). Using nationwide Danish registers, we tested the hypothesis that multimorbidity and SEP affect treatment patterns and adherence to pharmacological therapies in first-time HTx recipients. Pharmacological management included cost-free immunosuppressants and adjuvant medical treatment (preventive and hypertensive pharmacotherapies; loop diuretics). We enrolled 512 recipients. The median (IQR) age was 51 years (38–58 years) and 393 recipients (77%) were males. In recipients with at least two chronic diseases, prevalence of treatment with antihypertensive pharmacotherapies and loop diuretics was higher. The overall prevalence of adherence to treatment with tacrolimus or mycophenolate mofetil was at least 80%. Prevalence of adherence to preventive pharmacotherapies ranged between 65% and 95% and between 66% and 88% for antihypertensive pharmacotherapies and loop diuretics, respectively. In socioeconomically disadvantaged recipients, both the number of recipients treated with and adherence to cost-free everolimus, lipid modifying agents, angiotensin-converting enzyme/angiotensin II inhibitors, calcium channel blockers, and loop diuretics were lower. In recipients with multimorbidity, prevalence of treatment with antihypertensive pharmacotherapies and loop diuretics was higher. Among socioeconomically disadvantaged recipients, both number of patients treated with and adherence to cost-free everolimus and adjuvant pharmacotherapies were lower.
Hyperspectral Imaging and Selected Biological Control Agents for the Management of Fusarium Head Blight in Spring Wheat
Authors: Rieker Martin E. G. , Lutz Maximilian A. , El-Hasan Abbas , Thomas Stefan , Voegele Ralf T. 
Published: October 2023

Fusarium spp. are important pathogens on cereals, capable of causing considerable yield losses and significantly reducing the quality of harvested grains due to contamination with mycotoxins. The European Union intends to reduce the use of chemical-synthetic plant protection products (csPPP) by up to 50% by the year 2030. To realize this endeavor without significant economic losses for farmers, it is crucial to have both precise early detection of pathogens and effective alternatives for csPPP. To investigate both the early detection of Fusarium head blight (FHB) and the efficacy of selected biological control agents (BCAs), a pot experiment with spring wheat (cv. ‘Servus’) was conducted under semi-field conditions. Spikes were sprayed with different BCAs prior to inoculation with a mixture of F. graminearum and F. culmorum conidia. While early detection of FHB was investigated by hyperspectral imaging (HSI), the efficiency of the fungal (Trichoderma sp. T10, T. harzianum T16, T. asperellum T23 and Clonostachys rosea CRP1104) and bacterial (Bacillus subtilis HG77 and Pseudomonas fluorescens G308) BCAs was assessed by visual monitoring. Evaluation of the hyperspectral images using linear discriminant analysis (LDA) resulted in a pathogen detection nine days post inoculation (dpi) with the pathogen, and thus four days before the first symptoms could be visually detected. Furthermore, support vector machines (SVM) and a combination of LDA and distance classifier (DC) were also able to detect FHB symptoms earlier than manual rating. Scoring the spikes at 13 and 17 dpi with the pathogen showed no significant differences in the FHB incidence among the treatments. Nevertheless, there is a trend suggesting that all BCAs exhibit a diminishing effect against FHB, with fungal isolates demonstrating greater efficacy compared to bacterial ones.