bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arterial revascularization in patients with hand pain dialyzing with upper arm Arteriovenous (AV) fistulas: A single center experience
Authors: Balamuthusamy Saravanan , Dhanabalsamy Nisha , Bala Manu S , Reddy Prashant , Siddiqui Ayla , Ellappan Manonmani , Gopalakrishnan Sowmya , Nguyen Peter 
Published: December 2023

Background: Distal hand ischemia syndrome (DHIS) is a well reported adverse outcome in patients with upper arm AV access. 25%–40% of these patients have been reported to be due to primary arterial disease complicated with significant arterial calcification. The effectiveness of revascularization of the distal arterial circulation on symptom resolution has not been reported yet. Methods: Retrospective single center analysis of patients evaluated for hand/forearm pain in patients with upper arm AV access who had arterial revascularization between 01/2016 and 12/2020 were included for the analysis. Fifty-one patients met inclusion criteria. Stenotic lesions greater than 70% in the subclavian, axillary, brachial, radial, or ulnar artery were treated with balloon angioplasty. Institutional approval was obtained to review charts. Outcomes: Successful revascularization, improvement in pain in 48 h, 1 month, and 3 months. Results: Seventy six percent of patients had an upper arm Arteriovenous Fistula (AVF) and 24% patients had an upper arm Arteriovenous Graft (AVG). Mean access flow was 1210 (556) ml/min. 55% of patients had radial or ulnar arterial stenosis, 45% had brachial/axillary or subclavian artery stenosis. 45% patients had lesions in both radial and ulnar arteries, 88% of patients were successfully revascularized. 76% (18) of patients had improvement in symptoms within 48 h and 68% remained symptom free in 3 months. Mean DHIS stage was 3.1 before intervention and improved to 1.1 post intervention ( p < 0.001). Patient satisfaction with their AV access improved from 34% to 72% ( p < 0.01). Multiple regression analysis did not reveal statistically significant correlations between time on dialysis vintage and other chronic medical conditions on post procedure symptom improvement. Conclusions: DHIS with occlusive arterial disease can be successfully revascularized to improve symptoms. Complete evaluation of the inflow arterial segment and optimal endovascular revascularization could decrease the need for access revision procedures or access abandonment.
The Relationship Between the Wrist Flexion Creases and the Volar Radiocarpal Joint: A Cadaveric Study
Authors: Rust Andrew R. , Jain Sonu A. 
Published: December 2023

Background: Surgical approaches to the volar radiocarpal joint have historically entailed wide exposure, possibly contributing to poor wound healing and wrist denervation. To avoid wound complications and wrist denervation, minimally invasive and percutaneous approaches to the volar radiocarpal joint have been proposed. To help guide these minimally invasive or percutaneous approaches to the joint, we sought to characterize the relationship between the volar wrist flexion creases and the volar radiocarpal joint. We propose that the wrist flexion creases will be a reliable method for localizing the joint. Methods: Ten cadaveric upper-extremity specimens consisting of fingertip to mid forearm were obtained. Measurements from the proximal and distal wrist flexion creases were taken via fluoroscopy and gross dissection. Results: The wrist flexion creases were located distal to the volar radiocarpal joint in all specimens. The volar radiocarpal joint was located 7 and 16 mm proximal to the proximal and distal wrist flexion creases, respectively. The radiographic anatomy correlated well with the underlying deep anatomy. Conclusions: The wrist flexion creases can serve as a reliable superficial landmark for the identification of the volar radiocarpal joint. These landmarks aid clinicians in performing or interpreting a physical examination or in performing minimally invasive or percutaneous approaches to the volar radiocarpal joint.
The Duration of Bone Healing and Nonunion Ratio After Ulnar Shortening Osteotomy Using a 5-Hole Forearm Compression Plate With Transverse Osteotomy
Authors: Hama Shunpei , Moriya Koji , Koda Hisao , Tsubokawa Naoto , Maki Yutaka , Nakamura Hiroaki 
Published: December 2023

Background: Ulnar shortening osteotomy using various osteotomy sites, osteotomy methods, and surgical techniques with a variety of implants has been reported, but nonunion rates and the duration of bone healing are not uniform by the authors. The purpose of this study was to investigate the duration of bone healing and nonunion ratio in patients who underwent ulnar shortening osteotomy by a 5-hole nonlocking plate with a simple transverse osteotomy for ulnar impaction syndrome and to determine the correlation between the gap length of the osteotomy site and the duration of bone healing. Methods: We assessed patients who underwent ulnar shortening osteotomy for ulnar impaction syndrome using a 5-hole nonlocking plate fixation followed by a simple transverse osteotomy between July 2012 and October 2021. This study was a case series study, and the level of evidence was IV. Results: A total of 80 patients were included. The mean age of the patients was 46.7 years, and 46 patients were men. The average bone union period was 41.8 ± 18.7 weeks. The correlation between the gap length of the osteotomy site and the duration of bone union of the osteotomy site was not significant. The nonunion ratio of our method was 2.5%. Conclusion: The nonunion rate of our ulnar shortening osteotomy with a simple transverse osteotomy and a 5-hole nonlocking plate was comparable to that in previous reports, but our method required slightly longer periods for bone union. There was no correlation between the gap length of the osteotomy and the duration of bone union. Level of Evidence: Level IV (Case series)
Student’s perspectives, satisfaction and experiences with online and classroom learning during the COVID-19 pandemic: Findings and implications on blended learning
Authors: Mudenda Steward , Daka Victor , Mufwambi Webrod , Matafwali Scott Kaba , Chabalenge Billy , Skosana Phumzile , Mfune Ruth Lindizyani , Kasanga Maisa , Okonji Osaretin Christabel , Mayoka Godfrey , Kampamba Martin , Hikaambo Christabel Nang’andu , Mukosha Moses , Kanaan Manal Hadi Ghaffoori , Zikalala-Mabope Lindi Angeline , Sinkamba George , Okoro Roland Nnaemeka , Chulu Martha , Godman Brian , Fadare Joseph 
Published: December 2023

Objectives: The coronavirus disease 2019 (COVID-19) pandemic disrupted classroom-based learning, necessitating the adoption of online learning in most universities. However, there has been a lack of information on university students’ perspectives regarding online learning during the COVID-19 pandemic. This study assessed the perspectives, satisfaction and experiences with online and classroom learning among human health students at the University of Zambia. Methods: This cross-sectional study was conducted among 737 students at the University of Zambia from October 2022 to April 2023. Data were analysed using Stata version 16.1. Results: Of the 737 participants, 51.6% were female and 56.5% agreed that blended learning should continue even after the COVID-19 pandemic. However, 78.4% of the students believed that group discussions were more suitable in the classroom than online learning. Most students (67.1%) disagreed that they preferred online learning to classroom learning. Furthermore, 77.6% of the students disagreed that online learning gave more satisfaction than classroom learning. Conclusions: This study found that most students recommended the continuation of blended learning after the pandemic. However, they believed that follow-up tutorials and assessments were better undertaken in physical classrooms than online learning. These findings are important in sensitising stakeholders in the education sector and governments to consider blended learning as a teaching strategy in the future. There is a need to develop and implement curricula that offer blended learning to students as well as ensure the students have the necessary facilities and equipment to support such learning.
Targeting the tissue factor coagulation initiation complex prevents antiphospholipid antibody development
Authors: Müller-Calleja Nadine , Grunz Kristin , Nguyen T. Son , Posma Jens , Pedrosa Denise , Meineck Myriam , Hollerbach Anne , Braun Johannes , Muth Sabine , Schild Hansjörg , Saar Kathrin , Hübner Norbert , Krishnaswamy Sriram , Royce Jennifer , Teyton Luc , Lemmermann Niels , Weinmann-Menke Julia , Lackner Karl J. , Ruf Wolfram 
Published: December 2023

Abstract
Antiphospholipid antibodies (aPL) in primary or secondary antiphospholipid syndrome (APS) are a major cause for acquired thrombophilia, but specific interventions preventing autoimmune aPL development are an unmet clinical need. Although autoimmune aPL cross react with various coagulation regulatory proteins, lipid-reactive aPL, including those derived from patients with COVID-19, recognize the endolysosomal phospholipid lysobisphosphatidic acid presented by the cell surface–expressed endothelial protein C receptor. This specific recognition leads to complement-mediated activation of tissue factor (TF)–dependent proinflammatory signaling and thrombosis. Here, we show that specific inhibition of the TF coagulation initiation complex with nematode anticoagulant protein c2 (NAPc2) prevents the prothrombotic effects of aPL derived from patients with COVID-19 in mice and the aPL–induced proinflammatory and prothrombotic activation of monocytes. The induction of experimental APS is dependent on the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex, and NAPc2 suppresses monocyte endosomal reactive oxygen species production requiring the TF cytoplasmic domain and interferon-α secretion from dendritic cells. Latent infection with murine cytomegalovirus causes TF cytoplasmic domain–dependent development of persistent aPL and circulating phospholipid-reactive B1 cells, which is prevented by short-term intervention with NAPc2 during acute viral infection. In addition, treatment of lupus prone MRL-lpr mice with NAPc2, but not with heparin, suppresses dendritic-cell activation in the spleen, aPL production and circulating phospholipid-reactive B1 cells, and attenuates lupus pathology. These data demonstrate a convergent TF-dependent mechanism of aPL development in latent viral infection and autoimmune disease and provide initial evidence that specific targeting of the TF initiation complex has therapeutic benefits beyond currently used clinical anticoagulant strategies.
Proteomic Profiles Associated With Postsurgical Progression in Nonfunctioning Pituitary Adenomas
Authors: Hallén Tobias , Johannsson Gudmundur , Thorsell Annika , Olsson Daniel S , Örndal Charlotte , Engvall Angelica , Jacobson Frida , Widgren Anna , Bergquist Jonas , Skoglund Thomas 
Published: December 2023

Abstract

Context
There is a lack of reliable biomarkers capable of predicting postoperative tumor progression of nonfunctioning pituitary adenomas (NFPAs).

Objective
To discover proteomic profiles associated with postoperative tumor progression in patients with NFPAs. This was a case-controlled exploratory study at a tertiary university hospital. Tissue samples were obtained from 46 patients with residual tumor following surgery for NFPAs of gonadotroph lineage. Two patient groups were compared: patients requiring reintervention due to residual tumor progression (cases; reintervention group, n = 29) and patients with a residual tumor showing no progression for a minimum of 5 years (controls; radiologically stable group, n = 17). Differentially expressed proteins (DEPs) between patient groups were measured.

Results
Global quantitative proteomic analysis identified 4074 proteins, of which 550 were differentially expressed between the 2 groups (fold change &gt;80%, false discovery rate–adjusted P ≤ .05). Principal component analysis showed good separation between the 2 groups. Functional enrichment analysis of the DEPs indicated processes involving translation, ROBO-receptor signaling, energy metabolism, mRNA metabolism, and RNA splicing. Several upregulated proteins in the reintervention group, including SNRPD1, SRSF10, SWAP-70, and PSMB1, are associated with tumor progression in other cancer types.

Conclusion
This is the first exploratory study analyzing proteomic profiles as markers of postoperative tumor progression in NFPAs. The findings clearly showed different profiles between tumors with indolent postoperative behavior and those with postoperative tumor progression. Both enriched pathways involving DEPs and specific upregulated proteins have previously been associated with tumor aggressiveness. These results suggest the value of proteomic profiling for predicting tumor progression in patients with NFPAs.
Verlo todo con los propios ojos: Medicina legal y policía científica en Colombia, 1886–1930
Authors: Hering Torres Max S. 
Published: December 2023

Abstract
Este artículo tiene por objetivo analizar los cruces entre la medicina legal y el naciente ejercicio de policía científica como un intento del Estado por hacer legible la criminalidad. Para realizar este propósito se analiza el papel que tuvieron la Oficina Central de Investigación Criminal (1911) y la Oficina Central de Medicina Legal de Bogotá (1914) en la historia de Colombia, entre 1886 y 1930. Si bien ambas instituciones han sido abordadas en la historiografía, no han sido investigadas en su conexión. En este texto queda claro que la alianza entre médicos legistas y policía científica –siempre con el deseo de verlo todo– pasa más bien por una zona gris de incertidumbres. En esta medida, la reflexión histórica permite entender cómo las instituciones fabrican, en medio de la incertidumbre, sus discursos y crean un efecto de certeza, de infalibilidad y de convicción, mientras que en las prácticas se oscila entre el desinterés, la impotencia, la duda, la criminalización, la impunidad y, en algunos casos también, el acierto.
2024 ACSM Worldwide Fitness Trends: Future Directions of the Health and Fitness Industry
Authors: Newsome A'Naja M. , Reed Rachelle , Sansone Jessica , Batrakoulis Alexios , McAvoy Cayla , W. Parrott Matthew 
Published: December 2023

Apply It!
This article will inform and help readers to:
• Identify predictions for the top 20 fitness trends in the United States and across the globe for 2024.
• Use data to inform health and fitness business decisions and professional development.
• Recognize trend themes and region-specific needs to support consumer health and fitness.
Bright source of narrowband polarization-entangled photons from a thick type-II ppKTP crystal
Authors: Omshankar  , Venkataraman Vivek , Ghosh Joyee 
Published: December 2023

We demonstrate a high brightness (∼2.36 × 105 pairs/s/mW) polarization-entangled photon-pair source at 800-nm via spontaneous parametric down-conversion (SPDC) in a 3-cm long type-II ppKTP crystal pumped unidirectionally in a single-pass geometry. A high coincidences-to-accidentals ratio (CAR ∼ 1200) depicted by our source indicates a strong temporal correlation between the generated photon pairs. This correlated photon source is tunable from collinear to non-collinear emission of the photons and over a range of signal/idler wavelengths ∼8 − 9 nm corresponding to a temperature range of 20–60°C. We measure a quantum state fidelity F>95% with the singlet entangled state |ψ−⟩=12(|HV⟩−|VH⟩) along with a violation of the CHSH-Bell’s inequality by ∼485 standard deviations (S = 2.68 ± 0.0014).
Innovative and Marketing Features of Agri-Food Supply Chain Development
Authors: YASNOLOB Ilona , DEMIANENKO Nataliia , GORB Oleg , TIUTIUNNYK Yurii , TIUTIUNNYK Svitlana , SHULGA Lyudmyla , DUGAR Tetiana , MAIBORODA Olena , PYSARENKO Svitlana , POMAZ Yuliia 
Published: December 2023

The article emphasises that geopolitical instability (russian aggression in Ukraine, sanctions, tensions between the US and China, inflation, recession) has a negative impact on agri-food chains. In particular, the war in Ukraine is affecting Africa by increasing food prices, destabilising the situation and creating the threat of famine.
The article examines the export challenges faced by Ukraine during the war. Smart solutions provided in Ukraine and around the world in order to develop export opportunities are analysed. The specifics of investing in nearshoring production are investigated. The market of “digital logistics” as a set of services and tools for transportation is analysed.
The research studied digital platforms that can effectively manage cross-border transport in a single system and optimise the many business processes involved. Services that help to track real-time information on cargo, their location and transport conditions are analysed. They allow customers to reduce downtime costs, assess the efficiency of carriers, monitor cargo condition and quality.
This article focuses on the warehouse automation industry. In particular, it notes that robotic devices are already capable of sorting parcels, transporting them within warehouses and moving them from one shelf to another.
Particular attention is paid to the further transition to safer raw materials. The operators proposed to use green energy sources and support suppliers focused on renewable energy.
The main trends in 2023-2024 are expected to be the development of technology, flexibility, further transition to “green” solutions and other ways of developing the logistics market both in Ukraine and globally.
It is determined that Ukraine will be rebuild according to the principle of Build Back Better, in particular, it will build everything according to new rules and to the extent required, based on new realities.
Influence of Digital Technologies on Transition to a Circular Economy in Tourism: Values and Barriers
Authors: NASSANBEKOVA Samalgul , YESHENKULOVA Gaukhar , IBADILDIN Nurkhat 
Published: December 2023

Circular economy (CE) designed as a socio-economic system where resources are maintained for a long term with minimal leakage and waste, making them circular through closing, narrowing and slowing resource loops. In this system, we should not only consider materials and technical resources but also human capital. Creating circular business strategies is one of the paradigms of sustainable development and has potential to achieve many of the SDGs. Digital technologies (DT) enable this movement to CE including in the service sectors as a tourism. The aim of this paper is to identify how DT supports the transition to CE in tourism (CET). In this study, we conducted semi-structured interviews with 12 experts from tourism, CE and DT fields. Findings determined main values created by DT in CET, with special attention to values for human development, and existing barriers to utilize whole potential of DT for CET. This study contributes to conceptualization of knowledge about the role of digitalization in transition to CE in tourism and outlines future research areas.
Structured abstract: Purpose: to show how DT aids in the transformation of tourism to CE business model, by examine values created by DT for CE in tourism and human development and determine barriers for DT in transition to CE in tourism.
Design/methodology/approach: In this study, we applied semi-structured interviews with experts. To address study subjects, we employed a non-random judgment sampling strategy. Twelve specialists in total participated in semi-structured interviews.
Findings: Enhancing community participation, provide educational and training resources, access to information about sustainable tourism practices – are values created by DT for social development in tourism. Findings from the study suggest that DT can provide platforms for collaboration and innovation in tourism development. This can lead to new business models, products, and services that are more sustainable, inclusive, and resilient. However, in order to utilize DT in CET more effectively required particular economic, social, legal conditions, in the other word there are barriers and challenges.
Originality: The present study reveals roles of DT for transition to CE in tourism particularly outlining human-centered approach. The exciting frameworks considering links between DT and CE in the literature mainly directed for closing, narrowing and slowing material resource flow and only few included human capital. In this study, we outlined the main DT important for transition to CE in tourism, values created by this DT for CE and human development in tourism and existing barriers for them.
Assessment and Forecast of Atmospheric Air Quality at the Regional Level. Example of Central Kazakhstan
Authors: BEISENOVA Raikhan , ZHUMASHEV Bektemir , TAZITDINOVA Rumiya , RAKHYMZHAN Zhanar , TULEGENOVA Symbat , ZHAZNAYEVA Zhanat 
Published: December 2023

One of the main issues of environmental protection is the quality of atmospheric air. The reason for this is that all life on Earth, first of all, needs air, which affects all climatic and biological processes in general. Harmful and dangerous impurities can be transferred alongside the movement of air masses. These problems are especially acute in industrialized regions, where the level of anthropogenic impact is increasing. These regions include Central Kazakhstan.
When studying the issues of ecological and economic development of such regions, it is necessary to consider all possible consequences of anthropogenic impact that affect or may affect the atmospheric air. The main factor which plays a key role in this is strengthening the forecasting functions of environmental monitoring services, in our case, in relation to atmospheric air, and, when drawing up a plan for the infrastructure of the territories, taking into account the level of anthropogenic impact.
The Legal Framework Governing the Offence of Environmental Pollution in Jordan and the Sultanate of Oman
Authors: GHARIBEH Ashraf Mohamad , MAKHMARI Mohammed Rashid Ahmed Al , HAF Radwan Ahmad Al , ELAYAT Mohammad Njim Ibrahim , ALSHARQAWI Ahmad Hussein 
Published: December 2023

The focus of this study pertains to the legal regulations governing environmental pollution offences, as stipulated by the Environmental Protection Law No. 6 of 2017 and its subsequent revisions. Initially, the study examined the definitions of environmental pollution in accordance with the methodology employed by Jordanian lawmakers and international conferences. Subsequently, an analysis was conducted on the Environmental Protection Law No. 6 of 2017 and its subsequent amendments. This was followed by a determination of the fundamental components upon which the criminal offence is predicated. Additionally, a review of select cases that were brought before the Jordanian judiciary was undertaken.
The environmental policy in Oman legislation underscores adopting a multifaceted approach, sometimes emphasizing obligatory measures and resorting to prohibitive or unrestricted policies. It is apparent that the responsibility for safeguarding the environment from pollution is not solely vested in the state but is a collective responsibility shared among individuals and society as a whole, as reinforced by the provisions of Article 6. This underscores the importance of environmental protection as an effective means to combat wrongdoing, thus the enactment of Law No. 26 for Environmental Protection and Pollution Control, which establishes specific legal principles to define criminal behaviour and prescribes penalties, adhering to the fundamental legal principle that "there is no crime and no punishment except by law."