bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sosialisasi “Calling and Career” melalui program Career Day di kalangan murid SMAK IPEKA Balikpapan
Authors: Alfian Alfian Samudra 
Published: November 2023

Manusia diciptakan oleh Allah dengan sebuah tujuan utama yaitu untuk menikmati Allah serta memuliakan Allah. Jika merujuk pada tujuan tersebut, seluruh keberadaan manusia patut mengarah kepada Allah termasuk pekerjaan. Salah satu bentuk sikap memuliakan Allah dalam pekerjaan adalah dengan melakukan pekerjaan yang sesuai dengan panggilan Allah yaitu selaras dengan desain yang Allah telah siapkan dalam diri setiap manusia. Oleh karena itu, diperlukan sebuah wadah untuk menolong setiap peserta didik menemukan pekerjaan yang cocok dengan desain yang Allah telah siapkan. Salah satu wadah tersebut adalah program career day guna memperlihatkan kepada setiap peserta didik SMAK IPEKA Balikpapan agar bisa mengenali panggilan yang Tuhan berikan kepada mereka melalui pengenalan diri serta pengetahuan terhadap kebutuhan dunia masa kini dan juga menolong peserta didik untuk melihat ragam karier sebagai sebuah referensi karier di masa yang akan datang.
Kata Kunci: Program Career Day, Pekerjaan, Panggilan, Pengenalan diri
Sosialisasi dan Pelatihan Pemanfaatan Limbah Kain Menjadi Ornamen Dekorasi Interior Rumah Tinggal di Pulau Harapan
Authors: Ulinata Ulinata , Erwin Bambang , Sudarwani Margareta Maria , Nainggolan Susanti Muvana , Simatupang Sahala 
Published: November 2023

Kegiatan Pengabdian kepada Masyarakat yang dijalankan Program Studi Arsitektur FakultasTeknik UKI mengangkat tema Green Action 28 Sosialisasi dan Pelatihan Pemanfaatan Limbah Kain Menjadi Ornamen Dekorasi Interior Rumah Tinggal Di Pulau Harapan. Kegiatan ini merupakan lanjutan dari Kegiatan Pengabdian kepada Masyarakat sebelumnya yang bertujuan untuk mengedukasi masyakat mengenai desain dan pembuatan mini garden yang dapat dimanfaatkan sebagai penambahan ruanghijau terbuka pada rumah tinggal. Metodenya dengan mengadakan sosialisasi dan Workshop yang menghadirkan narasumber yang pakar di bidangnya sehingga para peserta memperoleh edukasi mengenai cara mendesain dan membuat Limbah Kain Menjadi Ornamen Dekorasi Interior Rumah Tinggal sehingga peserta dapat secara mandirimelakukannya di rumah tinggalnya serta menularkannya kepada tetangga maupun keluarganya yang belum pernah ikut serta dalam sosialisasi dan pelatihan tersebut. Prosesnya yaitu peserta mempraktikkan langsung dengan limbah kain perca yang dibawa oleh masing-masing peserta yang dapat dikreasikan sehingga menjadi elemen dekorasi interior pada rumah tinggal sehingga lebih estetis. Pada pelatihan ini juga diadakan sesi tanya jawab kepada para peserta.

Kata Kunci: Green Action, Kain Perca, Pulau Harapan
Pelatihan Pengolahan Sumber Daya Hasil Laut Kepada Kelompok Pemberdayaan Usaha dan Potensi (KPUP) Desa Sungai Kakap
Authors: Saragih Fry Melda , William Wendy Ary  , Fitri Yutika  
Published: November 2023

Abstrak
Ekonomi biru telah menjadi sektor unggulan yang ada di Indonesia dan berkontribusi besar atas perekonomian di Indonesia melalui produktivitas hasil laut dan serapan tenaga kerja. Desa Sungai Kakap merupakan salah satu desa yang terkenal dengan potensi hasil lautnya di Provinsi Kalimantan Barat. Namun, permasalahan terkait pengolahan produk kelautan menjadi produk olahan alternatif yang bernilai tinggi menjadi permasalahan utama yang menghambat optimalisasi hasil kelautan di desa ini. Tujuan kegiatan pengabdian ini adalah untuk mencari solusi dari permasalahan tersebut dan membangun kemitraan dengan KPUP Desa Sungai Kakap. Metode yang digunakan dalam kegiatan pengabdian ini adalah Participatory Rural Appraisal (PRA) dan dilaksanakan secara bertahap yaitu 1) Identifikasi dan Analisis, 2) Perencanaan Pendampingan, 3) Pelaksanaan Pendampingan, 4) Monitoring dan Evaluasi, dan 5) Laporan Akhir. Hasil dari kegiatan pengabdian ini adalah mayoritas peserta yang hadir merasa sangat puas dan merasakan manfaat yang tinggi dari kegiatan pengabdian ini terutama pada aspek penyampaian materi dan penyediaan teknologi. Namun, pada aspek solusi dapat ditingkatkan kembali.
Kata Kunci: Ekonomi Biru; Pemberdayaan; Hasil Laut; Potensi; Sungai Kakap
Early incident and subsyndromal delirium in older patients undergoing elective surgical procedures: a randomized clinical trial of an avoid delirium protocol
Authors: Sachdev Alisha , Moges Yabtsega , Rubin Micah , Sremac Amanda C. , Arvanitakis Zoe , McCarthy Robert J. 
Published: November 2023

BackgroundPharmacological avoidance guidelines for preventing delirium have been suggested; however, there are limited pragmatic studies of these strategies. Early (&lt;24 h) delirium can be observed in the postoperative care unit and is associated with an increased risk of subsequent delirium. We examined the effectiveness of an avoid delirium protocol (ADP) in older (&gt;65 years) patients undergoing elective surgeries.MethodsThe randomized controlled trial assessed an ADP developed using the American Geriatric Society's Clinical Practice Guidelines for Postoperative Delirium in Older Adults, on early (&lt;24 h) incident or subsyndromal delirium. Delirium was assessed using the confusion assessment method before surgery, in the post-anesthesia care unit, and on postoperative day 1. The primary outcome of early delirium was the combined incidence of incident or subsyndromal delirium.ResultsEarly delirium was identified in 24/235 patients (10.2%) with a risk ratio of 1.27 (95% CI 0.59–2.73, P = 0.667) for patients randomized to the ADP. In cases with protocol adherence and no benzodiazepine use, early delirium was present in 10/73 (13.7%) compared to 14/148 (9.5%) in non-adherent cases [risk ratio 1.45 (95% CI 0.57–3.10, P = 0.362)]. Lower American Society of Anesthesiologists physical class [odds ratio 3.31 (95% CI 1.35–8.92, P = 0.008)] and an inpatient admission [odds ratio 2.67 (95% CI 1.55–4.87, P = 0.0002)] were associated with early delirium.ConclusionsOur findings suggest that pharmacological avoidance protocols limiting or avoiding the use of specific classes of medications are not effective in reducing early incident or subsyndromal delirium in older patients undergoing elective surgery.
SARS-CoV-2 particles promote airway epithelial differentiation and ciliation
Authors: Gonzalez-Rubio Julian , Le-Trilling Vu Thuy Khanh , Baumann Lea , Cheremkhina Maria , Kubiza Hannah , Luengen Anja E. , Reuter Sebastian , Taube Christian , Ruetten Stephan , Duarte Campos Daniela , Cornelissen Christian G. , Trilling Mirko , Thiebes Anja Lena 
Published: November 2023

Introduction: The Severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), which caused the coronavirus disease 2019 (COVID-19) pandemic, enters the human body via the epithelial cells of the airway tract. To trap and eject pathogens, the airway epithelium is composed of ciliated and secretory cells that produce mucus which is expelled through a process called mucociliary clearance.Methods: This study examines the early stages of contact between SARS-CoV-2 particles and the respiratory epithelium, utilizing 3D airway tri-culture models exposed to ultraviolet light-irradiated virus particles. These cultures are composed of human endothelial cells and human tracheal mesenchymal cells in a fibrin hydrogel matrix covered by mucociliated human tracheal epithelial cells.Results: We found that SARS-CoV-2 particles trigger a significant increase in ciliation on the epithelial surface instructed through a differentiation of club cells and basal stem cells. The contact with SARS-CoV-2 particles also provoked a loss of cell-cell tight junctions and impaired the barrier integrity. Further immunofluorescence analyses revealed an increase in FOXJ1 expression and PAK1/2 phosphorylation associated with particle-induced ciliation.Discussion: An understanding of epithelial responses to virus particles may be instrumental to prevent or treat respiratory infectious diseases such as COVID-19.
Circulating exosomes decrease in size and increase in number between birth and age 7: relations to fetal growth and liver fat
Authors: Díaz Marta , Casano Paula , Quesada Tania , López-Bermejo Abel , de Zegher Francis , Villarroya Francesc , Ibáñez Lourdes 
Published: November 2023

PurposeExosomes play a key role in cell-to-cell communication by transferring their cargo to target tissues. Little is known on the course of exosome size and number in infants and children.MethodsLongitudinally, we assessed the size and number of circulating exosomes at birth and at ages 2 and 7 yr in 75 infants/children born appropriate-for-gestational-age (AGA; n=40) or small-for-gestational-age (SGA; n=35 with spontaneous catch-up), and related those results to concomitantly assessed measures of endocrine-metabolic health (HOMA-IR; IGF-1), body composition (by DXA at ages 0 and 2) and abdominal fat partitioning (subcutaneous, visceral and hepatic fat by MRI at age 7).ResultsCirculating exosomes of AGAs decreased in size (on average by 4.2%) and increased in number (on average by 77%) between birth and age 7. Circulating exosomes of SGAs (as compared to those of AGAs) had a larger size at birth [146.8 vs 137.8 nm, respectively; p=0.02], and were in lower number at ages 2 [4.3x1011vs 5.6x1011 particles/mL, respectively; p=0.01] and 7 [6.3x1011vs 6.8x1011 particles/mL, respectively; p=0.006]. Longitudinal changes were thus more pronounced in SGAs for exosome size, and in AGAs for exosome number. At age 7, exosome size associated (P&lt;0.0001) to liver fat in the whole study population.ConclusionEarly-life changes in circulating exosomes include a minor decrease in size and a major increase in number, and these changes may be influenced by fetal growth. Exosome size may become one of the first circulating markers of liver fat in childhood.
Functional lightweight protective clothing shielding design for constant radiation shielding of flight attendants and Monte Carlo simulation verification
Authors: Kim Seon-Chil , Youn Sukwon 
Published: November 2023

The use of easily accessible shielding suits for personal defense by flight attendants to reduce occupational cosmic radiation exposure is attracting increasing attention. However, to ensure activity in a limited area, the flexibility of the thin film must be considered. Although several process technologies to reduce the thickness of the shielding fabric are available, nanofiber production through electrospinning is the most effective, and it is attracting attention owing to its excellent reproducibility of the shielding performance. Therefore, in this study, a general sheet and a nanofiber shielding sheet were manufactured, and their shielding performance was compared. In addition, the shielding effect of the nanofiber shielding sheet was verified under aircraft conditions via Monte Carlo simulation. The shielding performance for neutrons and gamma rays, which are the most common sources of cosmic radiation, was 17.5% and 15.2%, respectively, with the Ba-133 and Cs-137 sources in the 0.3 mm shielding fabric. The absorbed dose change with the 5 mm shielding fabric was 7 μGy/d for neutrons and 4.3 μGy/d for protons. The shielding fabric developed in this study is expected to have an active shielding effect when used as personal protective equipment (clothing) by aircrew.
Depth-driven patterns in lytic viral diversity, auxiliary metabolic gene content, and productivity in offshore oligotrophic waters
Authors: Tsiola Anastasia , Michoud Grégoire , Daffonchio Daniele , Fodelianakis Stilianos , Giannakourou Antonia , Malliarakis Dimitris , Pavlidou Alexandra , Pitta Elli , Psarra Stella , Santi Ioulia , Zeri Christina , Pitta Paraskevi 
Published: November 2023

IntroductionMarine viruses regulate microbial population dynamics and biogeochemical cycling in the oceans. The ability of viruses to manipulate hosts’ metabolism through the expression of viral auxiliary metabolic genes (AMGs) was recently highlighted, having important implications in energy production and flow in various aquatic environments. Up to now, the presence and diversity of viral AMGs is studied using -omics data, and rarely using quantitative measures of viral activity alongside.MethodsIn the present study, four depth layers (5, 50, 75, and 1,000 m) with discrete hydrographic features were sampled in the Eastern Mediterranean Sea; we studied lytic viral community composition and AMG content through metagenomics, and lytic production rates through the viral reduction approach in the ultra-oligotrophic Levantine basin where knowledge regarding viral actions is rather limited.Results and DiscussionOur results demonstrate depth-dependent patterns in viral diversity and AMG content, related to differences in temperature, nutrients availability, and host bacterial productivity and abundance. Although lytic viral production rates were similar along the water column, the virus-to-bacteria ratio was higher and the particular set of AMGs was more diverse in the bathypelagic (1,000 m) than the shallow epipelagic (5, 50, and 75 m) layers, revealing that the quantitative effect of viruses on their hosts may be the same along the water column through the intervention of different AMGs. In the resource- and energy-limited bathypelagic waters of the Eastern Mediterranean, the detected AMGs could divert hosts’ metabolism toward energy production, through a boost in gluconeogenesis, fatty-acid and glycan biosynthesis and metabolism, and sulfur relay. Near the deep-chlorophyll maximum depth, an exceptionally high percentage of AMGs related to photosynthesis was noticed. Taken together our findings suggest that the roles of viruses in the deep sea might be even more important than previously thought as they seem to orchestrate energy acquisition and microbial community dynamics, and thus, biogeochemical turnover in the oceans.
The effect of balance and gait training on specific balance abilities of survivors with stroke: a systematic review and network meta-analysis
Authors: Zhang Meng , Liang Zhide , Li Yali , Meng Jun , Jiang Xu , Xu Bichan , Li Haojie , Liu Tao 
Published: November 2023

BackgroundStroke, which is a common clinical cerebrovascular disease, causes approximately 83% of survivors to suffer from balance impairments. Balance and gait training (BGT) is widely used to restore balance in patients with stroke. However, its wide variety presents clinicians with a dilemma when selecting interventions. This study aimed to compare and rank BGT interventions by quantifying information based on randomized controlled trials (RCTs).MethodsWe conducted a network meta-analysis (NMA) of non-gait-trained controls and head-to-head RCTs and compared the effects of 12 BGT interventions. A total of nine literature databases, including Medline, Embase, Cochrane Library, Web of Science, Scopus, SPORTDiscus, ClinicalTrials.gov, CNKI, and Chinese biomedical literature databases, were searched from their database inception to August 2023. Two authors independently selected studies and extracted data. The difference in outcomes, which were expressed as standardized mean differences and confidence intervals (CIs) of 95%, were explored in this meta-analysis.ResultsA total of 66 studies with 1,933 participants were included. Effect size estimates showed that not all BGT interventions were more effective than controls, with treadmill training as the least effective for balance test batteries (SMD = −0.41, 95% CI [−1.09, 0.27]) and proactive balance (SMD = −0.50, 95% CI [−1.14, 0.14]). Body-weight-supported treadmill training with external stimulation was most effective for proactive balance and dynamic steady-state balance (SMD = 1.57, 95% CI [−0.03, 3.16]); SMD = 1.18, 95% CI [0.67, 1.68]. Virtual reality gait training (SMD = 1.37, 95% CI [0.62, 2.11]) had the best effect on improving balance test batteries, while dual-task BGT (SMD = 1.64, 95% CI [0.50, 2.78]) had the best effect on static steady-state balance. After analyses for possible impact covariates, the findings through the outcomes did not change substantially. Confidence in the evidence was generally low or very low.ConclusionThis NMA suggested that virtual reality gait training was the most effective BGT modality for improving balance test batteries. Body-weight support treadmill training with external stimulation was the most effective for improving active and dynamic balance. In addition, dual-task BGT was the best choice for improving static balance. However, balance is a multidimensional concept, and patients’ different needs should be considered when selecting BGT.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022316057, ID: CRD42022316057.
Comparison of treprostinil and oral sildenafil for the treatment of persistent pulmonary hypertension of the newborn: a retrospective cohort study
Authors: Wei Enhuan , Chen Xiu-hua , Zhou Si-Jia 
Published: November 2023

BackgroundThis study aims to evaluate the effectiveness of treprostinil and oral sildenafil in managing persistent pulmonary hypertension of newborns (PPHN).MethodsWe conducted a retrospective cohort study of 42 neonates with PPHN treated with continuous intravenous treprostinil or oral sildenafil from January 2020 to October 2022 in China. Outcomes assessed included echocardiographic pulmonary artery systolic pressure (PASP), shunt direction, and arterial blood gas measures.ResultsTreprostinil lowered PASP and improved oxygenation significantly better than sildenafil on days 1, 2, and 3 of treatment (P &lt; 0.05). Treprostinil also corrected shunt direction faster than sildenafil (P &lt; 0.05). The duration of mechanical ventilation, length of NICU stay, and overall hospital stay did not significantly differ between the two groups (P &gt; 0.05).ConclusionsTreprostinil effectively lowers pulmonary artery pressure and improves oxygenation in neonates with PPHN, without being associated with severe complications. It may serve as a beneficial adjunct therapy for neonates with PPHN.
An analysis of the influencing factors of depression in older adults under the home care model
Authors: You Yanjie , Huang Lei , Peng Xiao , Liao Lulu , Zhang Fengjian , Feng Mingjiao , Chen Yuqin , Chang Hongwei , Mo Beirong , Liu Yilan 
Published: November 2023

ObjectivesTo explore and analyze the influencing factors of depression in older adults living at home, so as to propose suggestions for improving the quality of older adults living at home.MethodsWe conducted a cross-sectional study on 498 older adults living at home based on questionnaire survey on the general information, daily living ability, health status, and care perception (including self-care, care for cohabitants, and care for non-cohabitants) of older adults living at home, as well as their willingness to help each other, and analyzed the influencing factors of depression among older adults living at home.ResultsThe results showed a willingness to help older adults, self-care, and total activities of daily living (ADL), health status was an influential factor for depression in older adults (p &lt; 0.05).ConclusionIt aims to take targeted measures, such as encouraging older adults at home to actively participate in mutual assistance activities for older adults and care for themselves, so as to prevent and reduce the occurrence of depression in older adults.
HIV case reporting and HIV treatment outcomes in Qatar
Authors: Farag Elmoubashar , Bozicevic Ivana , Tartour Angham Ibrahim , Nasreldin Hiba , Daghfal Joanne , Himatt Sayed , Sallam Mohamed A. , Ismail Ahmed , Al Shamali Maha , Coyle Peter V. , Abdelmajid Alaaeldin , Al Mawlawi Naema , Al Thani Mohammed Hamad , Al-Romaihi Hamad Eid , Al Soub Hussam Abdel Rahman , Al Maslamani Muna , Al Khal Abdullatif 
Published: November 2023

AimThe aim of the paper is to provide an overview of available HIV case reporting and treatment data for in Qatar for the period 2015–2020.MethodsHIV case reporting data were analyzed by sex and mode of transmission. To construct HIV care continuum from the data available, we obtained information on the total number of HIV diagnosed patients on antiretroviral treatment (ART) between January 1st 2015 and December 31st 2020, number of patients on ART who had an HIV viral load test and the number who were virally suppressed (defined as having the viral load of less than 1,000 copies/mL).ResultsA total of 515 HIV cases were reported to the Ministry of Public Health since beginning of reporting in 1986, and that included Qatari nationals and expatriate residents diagnosed in Qatar. There was an increase in the annual number of newly reported HIV cases from 16 cases in 2015 (of these, 14 were males) to 58 cases in 2020 (of these, 54 were males). The total number of HIV diagnosed people on ART increased from 99 in 2015 to 213 in 2020. During 2020 the overall viral load testing coverage and viral load suppression among those tested for viral load in men were 72.5% and 93.1%, respectively, while in women these values were 60.4% and 84.4%, respectively.ConclusionDue to increase in newly reported HIV cases, there is a need to develop an effective HIV strategic information system in Qatar and data-driven and targeted national HIV response.
Public perceptions of the FDA’s marketing authorization of Vuse on Twitter/X
Authors: Lee Sarah , Xie Zidian , Xu Emily , Shao Yihan , Ossip Deborah J. , Li Dongmei 
Published: November 2023

IntroductionOn October 12, 2021, the FDA issued its first marketing granted orders for Vuse, the e-cigarette product by R.J. Reynolds Vapor Company. The public perceptions and reactions to the FDA’s Vuse authorization are prevalent on social media platforms such as Twitter/X. We aim to understand public perceptions of the FDA’s Vuse authorization in the US using Twitter/X data.MethodsThrough the Twitter/X streaming API (Application Programming Interface), 3,852 tweets between October 12, 2021, and October 23, 2021, were downloaded using the keyword of Vuse. With the elimination of retweets, irrelevant tweets, and tweets from other countries, the final dataset consisted of 523 relevant tweets from the US. Based on their attitudes toward the FDA authorization on Vuse, these tweets were coded into three major categories: positive, negative, and neutral. These tweets were further manually classified into different categories based on their contents.ResultsThere was a large peak on Twitter/X mentioning FDA’s Vuse authorization on October 13, 2021, just after the authorization was announced. Of the 523 US tweets related to FDA’s Vuse authorization, 6.12% (n=32) were positive, 26.77% (n=140) were negative, and 67.11% (n=351) were neutral. In positive tweets, the dominant subcategory was Cessation Claims (n=18, 56.25%). In negative tweets, the topics Health Risk (n=43, 30.71%), Criticize Authorization (n=42, 30.00%), and Big Tobacco (n=40, 38.57%) were the major topics. News (n=271, 77.21%) was the most prevalent topic among neutral tweets. In addition, tweets with a positive attitude tend to have more likes.DiscussionPublic perceptions and discussions on Twitter/X regarding the FDA’s Vuse authorization in the US showed that Twitter/X users were more likely to show a negative than a positive attitude with a major concern about health risks.