bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the efficiency of some weed control treatments on maize growth, and yield under high infestation by Ipomea eriocarpa and Setaria virdis soil seed banks
Authors: Abusteit Ezzaldin Omar , Absy Ragab , Ismail Abdo , Hassan Assem 
Published: January 2024

Abstract

Background Ipomea eriocarpa and Setaria virdis are widespread in maize fields in Egypt due to the recommended herbicides having less effect on one or every two species. Ipomea eriocarpa is twines on maize plants and breaks it as well as fewer pollution processes in maize, causing more damage to maize yield losses. The rotations of applied herbicides can overcome this problem, so, this work aims to evaluate the best sequence over two years for ten weed control treatments in sequence in maize fields chemical treatments with the fotowing six herbicides: Pendimethaline 45.5% CS (T1) at 3.6 l ha-1, Isoxaflutol 22.5%+Theincarbazone-methyl 9% SC Cyprosulfamide (safener) 10% SC (T2) at 360 cm3ha-1, Metribuzin 70% WG (T3) at 720 g ha-1, Foamsulfuron 3.35%+Iodosulfuron methyl-sodium 0.11%+Thiencarbazone-methyl 1.07% OD (T4) at 1200 cm3 ha-1, Foramsulfuron 2.25 OD (T5) at 1800 cm3 ha-1 and Bromoxynil 10%+Terbuthylanine 25% SE (T6) at 1200 cm3ha-1 with three hand hoeing treatment as mechanical weed control thrice (T7), twice (T8) and once (T9) and check weedy (untreated) (T10). Two field experiments were carried out at the experimental farm station, Agricultural Research Center, Giza, Egypt, during the 2021 and 2022 summer seasons in a randomized complete block design (RCBD).
Results showed that weed biomass was approximately 96 and 59.5 ton ha-1 in the 2021 and 2022 seasons, respectively, in the infested plots. The efficacy of treatments T2 and T4 were nearly equaled T8 and T9 under high infestation by Ipomea eriocarpa and Setaria vir dis during the first season, while treatments T1, T2, T4 and T5 were insignificantly different in reduced weed biomass as well as improvement maize growth, yield and its components than T8 in the second season as well as increased gross income and profitability of maize crop.
Conclusion according to the obtained results, the treatments T2, T4, T5, T1 and T7 or T8 as a rotation for two years were recommend for weed control and increased grain yield and profitability of maize.
Online BCI systems: cross-subject motor imagery classification based on weighted time-domain feature extraction methods
Authors: Yang Cheng , Wang Shiyu , Chen Xiaoyu , Peng Yiteng , Zhang Zhichao , Kong Lei , Zhou Chuyi , Tao Ye 
Published: January 2024

Abstract

Motor imagery electroencephalogram (MI-EEG) is becoming increasingly important. This paper solves the problem of online signal recognition for motor imagery across subjects by finding common features across multiple subjects to improve the generality of the classification model. We analyzed the EEG data from left/right-hand motor imagery of eight subjects and proposed a weighted time-domain (WTD) feature extraction method based on a weighted channel screening method. The classification model constructed by combining this feature extraction method with the support vector machine (SVM) classification method was faster in classification and achieved good cross-subject classification accuracy (The average offline classification accuracy was 91.39%). In this paper, an online control system for asynchronous brain-controlled wheelchairs was built with good performance. The online average motor imagery classification accuracy was 81.67%, and the average response time was 1.36s. This method contributes to bringing the online Brain-computer interface (BCI) system out of the laboratory and into wider application.
Mitochondrial calcium uniporter-mediated mitochondrial dynamics imbalance contributes to contrast medium-induced renal tubular cell injury
Authors: Huang Shuo , Lv Meiling , Chen Sha , Zhang Manyu , Yang Dingping , Hong Ge , Yang Dingwei 
Published: January 2024

Abstract
Background
Contrast-induced acute kidney injury (CI-AKI) is the acute onset of renal failure occurring 24–48 hours after intravascular injection of contrast medium (CM), which is a common cause of hospital-acquired acute kidney injury. Previous researches on CI-AKI have demonstrated that cytoplasmic Ca2+ overload and mitochondrial damage were strongly associated with CI-AKI, but the precise pathogenesis remains elusive. Therefore, we aimed to identify the role of mitochondrial calcium uniporter (MCU), the most important Ca2+ unidirectional channel of mitochondria, in CM-induced tubular epithelial cell injury and explore the molecular conformation of MCU interacting with iohexol.
Methods
Human renal proximal tubular epithelial (HK-2) cells were incubated with 100 mg I/ml iohexol. Cell injury and apoptosis were detected by Cell Counting Kit-8 and flow cytometry. The mitochondrial Ca2+ level was evaluated by Rhod-2 fluorescence. Mitochondrial damage was assessed by transmission electron microscopy, fluorescence of mitotracker, and JC-1. Protein expression of dynamin-related protein 1 (DRP1) and optic atrophy 1 (OPA1) was assessed by Western Blot.
Results
Iohexol administration successfully induced HK-2 cell injury and apoptosis. Moreover, there is an interaction between Iohexol and MCU. We also demonstrated that iohexol could lead to increase of mitochondrial Ca2+ concentration, upregulation of MCU expression, mitochondrial injury, and mitochondrial dynamics imbalance (excessive mitochondrial fission and loss of mitochondrial fusion) in HK-2 cells. Of note, inhibiting MCU by Ru360 efficiently maintaining mitochondrial function by reducing mitochondrial Ca2+ influx and improving impaired mitochondrial dynamics, thereby protecting HK-2 cells from CM-induced injury and apoptosis. On the contrary, the activation of MCU by spermine aggravated cell injury under the same mechanisms.
Conclusions
The present study illustrated a novel molecular mechanism of CI-AKI involving MCU-mediated mitochondrial dynamics imbalance, and suppression of MCU exhibited a cytoprotective effect on CM-treated renal tubular cells.
Colour Trademarks: A Creative Approach to Representing Green Brands and Sustainable Business Practices
Authors: R Jananipriya , B Ravi Kumar , S Usha , H Attchaya 
Published: January 2024

Abstract

Colours are important while marketing the products for its numerous benefits such as attracting consumers to distinguish one brand from another from one side, on the other hand, it optimises brand loyalty. Existing research has shown the significance of factors including social, economic, cultural, etc. at the time of selling a product as colourful, with special reference to the food and beverage sector. This study focuses on two perspectives; one, consumers' willingness to purchase eco-friendly products, and the other emphasis on colour trademarks as a new factor that affects consumer purchase intention using Mediation Analysis. This empirical study collected data through an online survey and received 139 responses based on the convenient sampling method. This study strives to test the hypothesis that, green brands mediate the relationship between colour trademark and purchase intention. The results show a positive relationship between the stated constructs, which is tested using SmartPLS 4.0 (Structural model method). The colour trademark significantly impacts the brands because consumers are confused between brands with colour logos of similar colours as it directly influences the purchase decision. This research has contributed to the awareness of green brands among consumers.
Temozolomide promotes matrix metalloproteinase 9 expression through p38 MAPK and JNK pathways in glioblastoma cells
Authors: Thanh Hien Duong , Lee Sueun , Nguyen Thuy Thi , Huu Thang Nguyen , Ahn Eun-Jung , Cho Sang-Hee , Kim Min Soo , Moon Kyung-Sub , Jung Chaeyong 
Published: January 2024

Abstract
Glioblastoma multiforme (GBM) is a highly aggressive and deadly brain cancer. Temozolomide (TMZ) is the standard chemotherapeutic agent for GBM, but many patients experience recurrence and invasion of tumor cells. We investigated whether TMZ treatment of GBM cells regulates matrix metalloproteinases (MMPs), which have main function to promote tumor cell invasion. TMZ effectively killed GL261, U343, and U87MG cells at a concentration of 500 µM, and surviving cells upregulated MMP9 expression and its activity but not those of MMP2. TMZ also elevated levels of MMP9 mRNA and MMP9 promoter activity. Subcutaneous graft tumors survived from TMZ treatment also exhibited increased expression of MMP9 and enhanced gelatinolytic activity. TMZ-mediated MMP9 upregulation was specifically mediated through the phosphorylation of p38 and JNK. This then stimulates AP-1 activity through the upregulation of c-Fos and c-Jun. Inhibition of the p38, JNK, or both pathways counteracted the TMZ-induced upregulation of MMP9 and AP-1. This study proposes a potential adverse effect of TMZ treatment for GBM: upregulation of MMP9 expression associated with increased invasion and poor prognosis. This study also provides valuable insights into the molecular mechanisms by which TMZ treatment leads to increased MMP9 expression in GBM cells.
WITHDRAWN: Exploring Adipsin, Irisin, and Osteopontin as Biomarkers in Polycystic Ovary Syndrome and Their Associations with Metabolic Alterations: A prospective, case-control study
Authors: Duzenli Fatma Nur , Yurtcu Engin , Keyif Betul , Basbug Alper 
Published: January 2024

Abstract

Background
Polycystic Ovary Syndrome (PCOS) is a prevalent endocrine disorder in premenopausal women, often associated with metabolic alterations. This study aimed to assess adipsin, irisin, and osteopontin levels and correlate the measurements with the metabolic changes in PCOS patients, with a scientific rationale rooted in exploring potential links between these biomarkers and the pathophysiology of PCOS.
Methods
A prospective, case-control study was conducted on patients diagnosed with PCOS. Group PCOS comprised patients with PCOS, while healthy women were included in Group Control. Serum adipsin, irisin, and osteopontin levels were measured, and various demographic and clinical characteristics and laboratory parameters related to the metabolic status of PCOS were assessed.
Results
The study included 96 PCOS patients and 80 healthy women. The patients in Group PCOS were significantly younger than those in Group Control (p < 0.001). There were significantly more obese patients in Group PCOS than in Group Control (p = 0.013). PCOS patients had higher serum adipsin (p = 0.020) and lower osteopontin levels (p < 0.001) than healthy women, with obesity and age influencing these differences. The predictive power of osteopontin, with an AUC value of 0.802, was superior to adipsin, with an AUC value of 0.602, in diagnosing PCOS. Besides, osteopontin, in combination with adipsin, had the highest AUC value (AUC = 0.817) than the other dual or triple combinations.
Conclusion
This study suggests potential links between adipsin, osteopontin, and irisin and PCOS. However, further research is needed to fully understand their roles and clinical implications in PCOS and its associated metabolic changes. The findings highlight the influence of age and obesity on these biomarkers and their relationship with PCOS, shedding light on the complex pathophysiology of the syndrome.
Design and Development of a Novel Tray Bioreactor for Optimization of Bacterial Nano-cellulose Production
Authors: Dermani Reza Khalili , Babaeipour Valiollah , Jabbari Farzaneh , Khanchezar Sirwan 
Published: January 2024

Abstract
In this research, a 30-liter bench-scale tray bioreactor was designed and built to increase bacterial cellulose (BC) production with a static culture system. Then, the effect of various parameters including the ratio of the volume to the surface of the culture medium in the tray, the aeration method, and inlet airflow on the increase of bacterial cellulose production in HS and molasses-gluten liquid culture media were investigated. Under the optimal conditions of volume-to-surface ratio of 1.16 cm and aeration rate of 1.5 vvm in the liquid molasses-gluten culture medium 8.23 g/L and 74.07 g of BC on each tray and the total amount obtained. In the following, to increase the scale and develop a system with easier use, an 80-liter incubator equipped with an aeration system was used along with trays with larger dimensions to provide the possibility of checking the ratio of volume to surface up to 3.8 cm. The results obtained can be used in higher scales as well. The amount of bacterial cellulose production in different volume-to-surface ratios was investigated. The results showed that the highest production value was obtained in the volume-to-surface ratio of 2.5, which is 8.63 g/L.
Failure’s Effect Analysis on Cloud Security using Markov Process
Authors: Goyal Nupur , Nawani Nikhil , Gupta Akansha 
Published: January 2024

Abstract
Cloud computing has become a crucial component in numerous industries. A lot of research has been done to make cloud more reliable. Despite that, there have been several instances where we have witnessed the shortcomings of cloud, not just due to external hacking attacks like DDoS but due to internal failures like misconfigurations as well. In this research work, the authors have analysed the performance of a cloud security through various reliability measures like reliability, availability and mean time to failure (MTTF) using Markov process and Laplace transformation. The authors have conducted an analysis of the obtained results to identify the primary causes of failures in the system, both internal and external-related. By controlling these causes, the overall reliability of the system can be improved, resulting in a faster and more effective cloud security.
Investigating the Determinants of Beds for High-Care Specialties in the Italian Regions in the Environmental, Social and Governance Model
Authors: Resta Emanuela , Resta Onofrio , Costantiello Alberto , Leogrande Angelo 
Published: January 2024

Abstract
In the following article, it is presented an investigation of the determinants of Beds for High-Care Specialties-BHCS in the Italian regions in the context of Environmental, Social and Governance-ESG approach. Data from ISTAT-BES for 20 countries in the period 2004-2021 are been used. Different econometric techniques have been applied i.e.: Pooled Ordinary Least Squares, Panel Data with Fixed Effects, Panel Data with Random Effects, Dynamic Panel at 1 stage. Furthermore, a cluster analysis performed with a k-Means algorithm optimized with the Silhouette Coefficient indicated the presence of three clusters. Finally, eight different machine-learning algorithms are analysed to predict the future value of BHCS. The results show that the Artificial Neural Network-ANN algorithm is the best algorithm. The future value of BHSC is expected to growth on average of 4.88% for the analysed regions.
JEL CODE: I11, I12, I13, I14, I15, I18
Luminescent Au-Ag nanoclusters entrapped in protein matrix: Conditions of sample maturing influencing Au-Ag synergistic effect
Authors: Svačinová Veronika , Pluháček Tomáš , Petr Martin , Šišková Karolína 
Published: January 2024

Abstract
Gold-silver synergism has been well documented in many scientific works already. Frequently, the ratio of Au : Ag in synthetic mixtures was varied to influence the extent of Au-Ag synergism. However, in our approach, a new step, maturing (under differing conditions) of the luminescent bimetallic samples entrapped in a protein, has been introduced and applied for the very first time. The maturing conditions involved either prolonged time (2.5h vs. 0 min) and/or elevated temperature (50 °C vs. room temperature). The prolonged time of samples maturing progressively influenced Au-Ag synergism (documented by fluorescent quantum yield increase); while elevated temperature during samples maturing led rather to changes of the protein secondary structure (determined by circular dichroism) and stagnation of Au-Ag synergism effect. Importantly, the selected maturing conditions led to significant increase of nanocluster sizes and broadening of particle size distribution as evidenced by scanning transmission electron microscopy (STEM) and dynamic light scattering (DLS). The results unravel that Au-Ag synergism can be tuned by setting appropriate maturing conditions of bimetallic nanoclusters embedded in the protein scaffold.
Short-term effects of the Strengthening Families Program (SFP 10-14) in Brazil: a randomized controlled trial
Authors: Sanchez Zila M , Valente Juliana Y , Gubert Fabiane A , Galvão Patricia P O , Cogo-Moreira Hugo , Rebouças Lidiane N , Santos Miguel Henrique S dos , Melo Marcia H S , Caetano Sheila C 
Published: January 2024

Abstract
This study discloses the evaluation of the short-term effect of the Strengthening Families Program (SFP 10-14), adapted as Famílias Fortes (Strong Families) in Brazil, on preventing adolescent drug use and improving parenting behaviors.
Methods: A two-arm, parallel cluster randomized controlled trial was conducted in 60 Social Assistance Reference Centers (SARC) in 12 Brazilian municipalities. In each city, the SARC were randomly assigned to the intervention or control group. Eight hundred five families participated in the study, each contributing data from one parent/guardian and one adolescent for a total of 1,610 participants. Data collection occurred before the implementation of the intervention, and 6 months after baseline collection. Data were analyzed using multilevel mixed-effects modeling with repeated measuresin two different paradigms: Intention to Treat (ITT) and Per protocol (PP). The study was registered in the Brazilian Ministry of Health Register of Clinical Trials (REBEC), under protocol number RBR-5hz9g6z.
Results: Considering the ITT paradigm, the program reduced the chance of parents/guardians being classified as negligent by 60% (95%CI 0.21; 0.78); increased the use of nonviolent discipline by caregivers (Coef 0.33, 95%CI 0.01; 0.64) and decreased the chance of adults exposing adolescents to their drunken episodes by 80% (95%CI 0.06; 0.54). No program effects were observed on outcomes related to adolescent drug use. Similar results were observed in the PP paradigm.
Conclusion: The positive results on family outcomes suggest preventive potential of the program in the Brazilian population. Long-term evaluations need to be conducted to verify if the program will also achieve the drug use reduction goals that were not found in the short term.
Correlation Between Early Postnatal Body Weight Changes and Lung Ultrasound Scores as Predictors of Bronchopulmonary Dysplasia in Preterm Infants; A Secondary Analysis of a Prospective Study
Authors: Ghanem Mohab , Zozaya Carlos , Ibrahim Jenna , Lee Seungwoo , Mohsen Nada , Nasef Nehad , Mohamed Adel 
Published: January 2024

Abstract
Purpose of the study: Recent research links Early Weight-Changes (EWC) with bronchopulmonary dysplasia (BPD) in preterm neonates, while lung ultrasound score (LUS) has shown promise in predicting BPD. We aimed to explore the correlation between LUS and EWC as markers of extravascular lung edema.
Objective: To investigate the correlation between LUS and EWC in preterm infants with respiratory distress syndrome regarding future BPD development.
Methods: This secondary analysis of a prospective study involved infants ≤ 28 weeks' gestation. Enrolled infants underwent lung ultrasound assessment on postnatal days 3, 7 and 14, measuring LUS. Respiratory severity score (RSS) and EWC were computed on the same time-points. Infants were classified as either having BPD or not. Descriptive statistics, Correlation Coefficient, and Area Under the Receiver Operating Characteristic Curve (AUROC) analysis were utilized.
Results: Of 132 infants, 70 (53%) had BPD. Univariate analysis revealed statistically significant differences in LUS, EWC, and RSS at days 3, 7, and 14 between BPD and no-BPD groups (p < 0.001). A statistically significant but weak positive correlation existed between LUS and EWC at all three assessment points. AUROC analysis indicated LUS having superior predictive capacity for the need for invasive mechanical ventilation at day 14 as well as the later BPD development compared to EWC (p < 0.0001).
Conclusions: In a cohort of extreme preterm infants, our study revealed a positive yet weak correlation between LUS and EWC, suggesting that EWC was not the major contributing to the evolving chronic lung disease.
Sol-Gel Assisted β-Cyclodextrin Coated MoO3-Fe2O3 Nanocomposite for Photodegradation of Methylene Blue Dye
Authors: Nagare Akash , Dhadage Amol , Baithy Mallesham , Bhuyan Priyanga Manjuri , Gogoi Parikshit , Athare Anil , Navgire Madhukar 
Published: January 2024

Abstract
In this work, series of β-Cyclodextrin coated MoO3-Fe2O3 nanocomposites were successfully synthesized by using the sol-gel technique to improve their optical properties with the photocatalytic activity of Fe2O3. The prepared materials were analyzed by using various characterization techniques like powder XRD, FT-IR, UV-DRS, FE-SEM, HR-TEM, RAMAN, BET, and XPS. The X-ray diffraction spectra analyzed that, it shows the nanocrystalline nature of synthesized materials. The indirect allowed transition optical energy band gap of nanocomposites is lies between 2.67 to 1.71 eV. The FE-SEM study revealed the nano-flakes to change occurs in the morphology of nanocomposites sample also it gives estimated size in between 30–50 nm. The BET analysis show mesoporous nature of nanocomposites and XPS spectra shows the elemental composition on surface of the synthesized sample. The proficiency of the nanocomposites was tested for the photodegradation of the methylene blue dye (MB) under sunlight at room temperature (25°C) in presence of H2O2. The pure MoO3 and Fe2O3 material gives 38.21% and 77.10% photodegradation of MB respectively. In series lies between 5% β-Cyclodextrin coated MoO3-Fe2O3 (5βMF) shows excellent photocatalytic activity which degrades 91.62% of MB at neutral pH. Thus, the photodegradation reaction is effectively attributed to charge carrier separation and reduced optical band gap energy due to enhanced photocatalytic activity.
Local Wisdom on Mangrove Management in Nipah Panjang Village, Indonesia
Authors: Fariz Trida Ridho , Permana Pawit Indra , Jabbar Abdul , Saoki Rafi Nadhifa , Purwadi Cintiya Egi 
Published: January 2024

Abstract

Indonesia is one of the countries that has the largest mangrove forest area. Although Indonesia is a country that has the largest mangrove forest in the world, several problems have caused the reduction of mangrove forest areas, so it requires strategic policies. Strategic mangrove management policies will be more easily applied in the community based on local wisdom in the region so that this study will discuss local wisdom in mangrove management in Nipah Panjang Village. This study is qualitative, with data collection using literature studies, interviews, and observations. This study shows that the existence of mangrove forests provides ecological and economic benefits for the people of Nipah Panjang Village. The economic benefit is that mangrove forests provide food and shelter for bees and Kelulut, which the community utilizes for honey. The cultivation process also has local wisdom values that aim to preserve mangrove forests, especially in forest honey cultivation. If mangrove forests are damaged, it will result in honey production, leading to the loss of community livelihoods. For this reason, it is necessary to make efforts to conserve mangroves.