bluuebunny/crossref_metadata_2025_split huggingface dataset:
A co‐rotational virtual element method for 2D elasticity and plasticity
Authors: Yaw Louie L. 
Published: December 2023

AbstractThe virtual element method (VEM) allows discretization of the problem domain with polygons in 2D. The polygons can have an arbitrary number of sides and can be concave or convex. These features, among others, are attractive for meshing complex geometries. VEM applied to linear elasticity problems is now well established. Nonlinear problems involving plasticity and hyperelasticity have also been explored by researchers using VEM. Clearly, techniques for extending the method to nonlinear problems are attractive. In this work, a novel first‐order consistent VEM is applied within a static co‐rotational framework. To the author's knowledge, this has not appeared before in the literature with virtual elements. The formulation allows for large displacements and large rotations in a small strain setting. For some problems avoiding the complexity of finite strains, and alternative stress measures, is warranted. Furthermore, small strain plasticity is easily incorporated. The basic method, VEM specific implementation details for co‐rotation, and representative benchmark problems are illustrated. Consequently, this research demonstrates that the co‐rotational VEM formulation successfully solves certain classes of nonlinear solid mechanics problems. The work concludes with a discussion of results for the current formulation and future research directions.
The theoretical and experimental buckling analysis of a nanocomposite beams reinforced by nanorods made of recycled materials
Authors: Bargozini F. , Mohammadimehr M. 
Published: December 2023

AbstractIn this article, the numerical and experimental results for buckling analysis of a nanocomposite beams reinforced by nanorods are studied and compared. The Chebyshev–Ritz method is used to calculate the buckling numerically and compare it with the buckling test. Epoxy resin, glass's fiber, and nanorods are used to make composites. These nanorods are made using recycled materials. Also, bending and tensile tests are used to obtain the properties of these composites. In addition, the effect of various parameters such as Young's modulus, temperature change, Poisson's ratio, and boundary conditions, the strain gradient parameter, and different shape function is investigated. The addition of nanorods increases the strength and stiffness of composites and increases the critical buckling load. Actually, the made nanorods are used as a reinforcement in matrix, thus in the made nanocomposites, fracture and buckling tests are done and the results indicate that the inclusion of nanorods (0.32%) increases the critical buckling load by 16.4%. A facile hydrothermal method to synthesis the nano rodes has a less cost with the other methods, thus by adding a small percentage of it to the composite, the stiffness of the structure increases. According to the results and the significant increase in Young's modulus and critical buckling load and the cost‐effectiveness of carbon nanorods (CNRs) made from recycled materials, these environmentally friendly reinforcements can be used in various industries such as machine body construction, automobile manufacturing, shipbuilding and construction of type's turbines.Highlights
Using potato peels and hydrothermal methods, CNRs produced.
These CNRs are useful, and production is cheap and no harm environmental.
Buckling sample include of glass fiber, without and with CNRs and epoxy resin.
Third order shear deformation beam theory and Chebyshev–Ritz are used
Theoretical and experimental buckling critical load are compared.
Therapeutic potential of propolis in alleviating inflammatory response and promoting wound healing in skin burn
Authors: Manginstar Christian Oktavianus , Tallei Trina Ekawati , Niode Nurdjannah Jane , Salaki Christina Leta , Hessel Sofia Safitri 
Published: December 2023

AbstractBurns can cause inflammation and delayed healing, necessitating alternative therapies due to the limitations of conventional treatments. Propolis, a natural bee‐produced substance, has shown promise in facilitating burn healing. This literature review provides a comprehensive overview of propolis' mechanisms of action, wound‐healing properties, and its application in treating skin burns. Propolis contains bioactive compounds with antimicrobial, antioxidant, and anti‐inflammatory properties, making it a promising candidate for managing skin burn injuries. It helps prevent infections, neutralize harmful free radicals, and promote a well‐balanced inflammatory response. Moreover, propolis aids in wound closure, tissue regeneration, collagen synthesis, cellular proliferation, and angiogenesis, contributing to tissue regeneration and remodeling. The article discusses various propolis extracts, extraction methods, chemical composition, and optimized formulations like ointments and creams for burn wound treatment. Considerations regarding dosage and safety are addressed. Further research is needed to fully understand propolis' mechanisms, determine optimal formulations, and establish suitable clinical dosages. Nevertheless, propolis' natural origin and demonstrated benefits make it a compelling avenue for burn care exploration, potentially complementing existing therapies and improving burn management outcomes.
Dynamic switched periodic event‐triggered control systems under denial‐of‐service attacks
Authors: Fu Anqi , Zhang Yan , Qiao Junfei 
Published: December 2023

AbstractPeriodic event‐triggered control (PETC) can save network bandwidth and sensor energy at the same time; therefore, it is a promising approach for applications, especially large scale plants, such as smart water distribution systems. This work extend PETC by considering denial of service (DoS) attacks. For the PETC, a dynamic variable is introduced with a switched strategy. Different from other dynamic variables, our variable keeps store energy when there is no attacks and only release energy when attacks happen. Thus, the inter‐event intervals when attacks happen can be prolonged while guarantees the same stability and performance. If the variable equals to 0 before the ending of the attacks, then characteristic of the attack duration is analyzed to guarantee a slower Lyapunov convergence rate. The presented approach is verified via a numerical example from smart water distribution systems.
Fine‐scale damage assessment of urban flooding based on the 1D/2D coupled hydrodynamic model
Authors: Dong Boliang , Xia Junqiang , Li Qijie , Wang Xiaojie 
Published: December 2023

AbstractDue to the high population density and economic property in urban environments, urban flooding can result in substantial economic losses. However, accurate urban flood modeling and assessing the associated damages are challenging due to complex urban layouts and rugged topography. Furthermore, the rapid development of urban underground spaces has introduced additional complexities. To address the demanding need for accurate flood modeling and damage assessment in cities, a fine‐scale flood damage assessment method was proposed in this study, based on the 1D/2D coupled hydrodynamic model, which can not only assess the flood damage on the ground surface but also evaluate the flood loss in underground spaces. Taking the Gangxi drainage area in Wuhan City, China as a case, this study extensively discussed the flood inundation processes on the ground surface as well as in the buildings and underground spaces, under different rainfall scenarios with the return period ranging from 2 to 200 years. Based on the high spatial‐temporal hydrodynamic simulations, the flood damage degrees were evaluated for the buildings and underground spaces with different industry types. The results indicated that the inundation of buildings and underground spaces in densely built cities cannot be neglected in urban flood modeling. Buildings with public service attributes can have a higher flood damage degree, as compared with other types of buildings and underground spaces.
Celebrating 100 Years of University of Delhi (1922–2022)
Authors: Awasthi Satish K. , Biswas Parbati , Singh Brajendra K. , Deka Sasanka , Kaur‐Ghumaan Sandeep 
Published: December 2023

AbstractUniversity of Delhi (DU) has attained global recognition for its research and teaching in Chemistry. This Guest Editorial introduces the research showcased in the “Institute Feature: Celebrating 100 Years of University of Delhi (1922–2022)” ‐ a joint special collection from the European Journal of Organic Chemistry (EurJOC), European Journal of Inorganic Chemistry (EurJIC) and ChemistrySelect The collection highlights the contributions to the field of chemistry through research articles and reviews authored by faculty members from the Department of Chemistry, alumni of the department and faculty members of chemistry department of various colleges affiliated with the university, celebrating 100 years of DU.
Neutrophil‐Mimetic, ROS Responsive, and Oxygen Generating Nanovesicles for Targeted Interventions of Refractory Rheumatoid Arthritis
Authors: Tang Zhuang , Meng Shiyu , Yang Xiaoxue , Xiao Yi , Wang Wentao , Liu Yonghang , Wu Kefan , Zhang Xican , Guo Hui , Zhu Yi Zhun , Wang Xiaolin 
Published: December 2023

AbstractRheumatoid arthritis (RA) is the most prevalent inflammatory joint disease worldwide, leading to irreversible disability and even mortality. Unfortunately, current treatment regimens fail to cure RA due to low therapeutic responses and off‐target side effects. Herein, a neutrophil membrane‐cloaked, natural anti‐arthritic agent leonurine (Leo), and catalase (CAT) co‐loaded nanoliposomal system (Leo@CAT@NM‐Lipo) is constructed to remodel the hostile microenvironment for RA remission. Due to the inflammation tropism inherited from neutrophils, Leo@CAT@NM‐Lipo can target and accumulate in the inflamed joint cavity where high‐level ROS can be catalyzed into oxygen by CAT to simultaneously accelerate the drug release and alleviate hypoxia at the lesion site. Besides, the neutrophil membrane camouflaging also enhances the anti‐inflammatory potentials of Leo@CAT@NM‐Lipo by robustly absorbing pro‐arthritogenic cytokines and chemokines. Consequently, Leo@CAT@NM‐Lipo successfully alleviated paw swelling, reduced arthritis score, mitigated bone and cartilage damage, and reversed multiple organ dysfunctions in adjuvant‐induced arthritis rats (AIA) rats by synergistic effects of macrophage polarization, inflammation resolution, ROS scavenging, and hypoxia relief. Furthermore, Leo@CAT@NM‐Lipo manifested excellent biocompatibility both at the cellular and animal levels. Taken together, the study provided a neutrophil‐mimetic and ROS responsive nanoplatform for targeted RA therapy and represented a promising paradigm for the treatment of a variety of inflammation‐dominated diseases.
Sequence‐Guided Localization of DNA Hybridization Enables Highly Selective and Robust Genotyping
Authors: Wang Xuchu , Chen Tao , Ping Ying , Dai Yibei , Yu Pan , Xie Yiyi , Liu Zhenping , Sun Bohao , Duan Xiuzhi , Tao Zhihua 
Published: December 2023

AbstractGenetic variations are always related to human diseases or susceptibility to therapies. Nucleic acid probes that precisely distinguish closely related sequences become an indispensable requisite both in research and clinical applications. Here, a Sequence‐guided DNA LOCalization for leaKless DNA detection (SeqLOCK) is introduced as a technique for DNA hybridization, where the intended targets carrying distinct “guiding sequences” act selectively on the probes. In silicon modeling, experimental results reveal considerable agreement (R2 = 0.9228) that SeqLOCK is capable of preserving high discrimination capacity at an extraordinarily wide range of target concentrations. Furthermore, SeqLOCK reveals high robustness to various solution conditions and can be directly adapted to nucleic acid amplification techniques (e.g., polymerase chain reaction) without the need for laborious pre‐treatments. Benefiting from the low hybridization leakage of SeqLOCK, three distinct variations with a clinically relevant mutation frequency under the background of genomic DNA can be discriminated simultaneously. This work establishes a reliable nucleic acid hybridization strategy that offers great potential for constructing robust and programmable systems for molecular sensing and computing.
Engineering Low‐Cost Organic Cathode for Aqueous Rechargeable Battery and Demonstrating the Proton Intercalation Mechanism for Pyrazine Energy Storage Unit
Authors: Niu Suyan , Wang Yao , Zhang Jianwen , Wang Yiming , Tian Yaxiong , Ju Na , Wang Haipeng , Zhao Shuya , Zhang Xinyue , Zhang Wenlong , Li Chengrui , Sun Hong‐bin 
Published: December 2023

AbstractSeeking organic cathode materials with low cost and long cycle life that can be employed for large‐scale energy storage remains a significant challenge. This work has synthesized an organic compound, triphenazino[2,3‐b](1,4,5,8,9,12‐hexaazatriphenylene) (TPHATP), with as high as 87.16% yield. This compound has a highly π‐conjugated and rigid molecular structure, which is synthesized by capping hexaketocyclohexane with three molecules of 2,3‐diaminophenazine derived from low‐cost o‐phenylenediamine, and is used as a cathode material for assembling aqueous rechargeable zinc ion batteries. Both experiments and DFT calculations demonstrate that the redox mechanism of TPHATP is predominantly governed by H+ storage. The Zn‐intercalation product of nitride‐type compound, is too unstable to form in water. Moreover, the TPHATP cathode exhibits a capacity of as high as 318.3 mAh g−1 at 0.1 A g−1, and maintained a stable capacity of 111.9 mAh g−1 at a large current density of 10 A g−1 for 5000 cycles with only a decay of 0.000512% per cycle. This study provides new insights into understanding pyrazine as an active redox group and offers a potential affordable aqueous battery system for grid‐scale energy storage.
A Dual‐Responsive Morphologically‐Adaptable Nanoplatform for Targeted Delivery of Activatable Photosensitizers in Precision Photodynamic Therapy
Authors: Jiao Qishu , Zheng Yaxin , Xie Qinqing , Luo Xuan , Zhou Shuyao , Pei Shicheng , Zhang Tingting , Wu Xiaoxing , Xu Keming , Zhong Wenying 
Published: December 2023

AbstractPhotodynamic therapy (PDT) is an effective approach for treating melanoma. However, the photosensitizers employed in PDT can accumulate in healthy tissues, potentially causing harm to normal cells and resulting in side effects such as heightened photosensitivity. To address this, an activatable photosensitizer (PSD) by linking PpIX with a fluorescence quencher using a disulfide bond is designed. PSD responded to endogenous GSH, showing high selectivity for A375 cells. To enhance PSD's bioavailability and anticancer efficacy, an enzyme‐responsive nanoplatform based on a lonidamine‐derived self‐assembling peptide is developed. Initially, PSD and the peptide self‐assembled into nanoparticles, displaying potent tumor targeting of PSD in vivo. Upon cell uptake, these nanoparticles specifically responded to elevated cathepsin B, causing nanoparticle disintegration and releasing PSD and lonidamine prodrug (LND‐1). PSD is selectively activated by GSH for cancer‐specific fluorescence imaging and precision PDT, while LND‐1 targeted mitochondria, forming a fibrous lonidamine depot in situ and intensifying photosensitizer's cytotoxicity through ROS generation, mitochondrial dysfunction, and DNA damage. Notably, intravenous administration of LND‐1‐PEG@PSD with light irradiation significantly suppressed A375‐xenografted mouse tumor growth, with minimal systemic toxicity. Together, the synergy of activatable photosensitizer and enzyme‐responsive nanoplatform elevates PDT precision and diminishes side effects, showcasing significant potential in the realm of cancer nanomedicine.
Recent Advances on Pulsed Laser Deposition of Large‐Scale Thin Films
Authors: Yu Jing , Han Wei , Suleiman Abdulsalam Aji , Han Siyu , Miao Naihua , Ling Francis Chi‐Chung 
Published: December 2023

Abstract2D thin films, possessing atomically thin thickness, are emerging as promising candidates for next‐generation electronic devices, due to their novel properties and high performance. In the early years, a wide variety of 2D materials are prepared using several methods (mechanical/liquid exfoliation, chemical vapor deposition, etc.). However, the limited size of 2D flakes hinders their fundamental research and device applications, and hence the effective large‐scale preparation of 2D films is still challenging. Recently, pulsed laser deposition (PLD) has appeared to be an impactful method for wafer‐scale growth of 2D films, owing to target‐maintained stoichiometry, high growth rate, and efficiency. In this review, the recent advances on the PLD preparation of 2D films are summarized, including the growth mechanisms, strategies, and materials classification. First, efficacious strategies of PLD growth are highlighted. Then, the growth, characterization, and device applications of various 2D films are presented, such as graphene, h‐BN, MoS2, BP, oxide, perovskite, semi‐metal, etc. Finally, the potential challenges and further research directions of PLD technique is envisioned.
Enhancing android application security: A novel approach using DroidXGB for malware detection based on permission analysis
Authors: Kumar Pawan , Singh Sukhdip 
Published: December 2023

AbstractThe prevalence of malicious Android applications targeting the platform has introduced significant challenges in the realm of security testing. Traditional solutions have proven insufficient in handling the growing number of malicious apps, resulting in persistent exposure of Android smartphones to evolving forms of malware. This study investigates the potential of extreme gradient boosting (XGB) in identifying complex and high‐dimensional malicious permissions. By leveraging attribute combination and selection techniques, XGBoost demonstrates promising capabilities in this area. However, enhancing the XGBoost model presents a formidable challenge. To overcome this, This research employs adaptive grey wolf optimization (AGWO) for hyper‐parameter tuning. AGWO utilizes continuous values to represent the position and movement of the grey wolf, enabling XGBoost to search for optimal hyper‐parameter values in a continuous space. The proposed approach, DroidXGB, utilizes XGBoost and AGWO to analyze permissions and identify malware Android applications. It aims to address security vulnerabilities and compares its performance with baseline algorithms and state‐of‐the‐art methods using four benchmark datasets. The results showcase DroidXGB's impressive accuracy of 98.39%, outperforming other existing methods and significantly enhancing Android malware detection and security testing capabilities.
Impact of exposure to glyphosate‐based herbicide on morphological and physiological parameters in embryonic and larval development of zebrafish
Authors: Durante Laíse da Silva , Hollmann Gabriela , Nazari Evelise Maria 
Published: December 2023

AbstractGlyphosate‐based herbicides (GBH) have been commonly used in agriculture to inhibit weed growth and increase yields. However, due to the high solubility of these herbicides in water, they can reach aquatic environments, by infiltration, erosion, and/or lixiviation, affecting non target organisms. Thus, this study aimed to characterize the toxicity of GBH Roundup WG® (RWG®) during the embryonic and larval development of Danio rerio. Embryos (3 hours post fertilization, hpf–until hatching) and larvae (3 days post fertilization, dpf to 6 dpf) were exposed to concentrations of 0.065 and 6.5 mg L−1. They were evaluated for survival, hatching, spontaneous movements, heartbeat, morphology, and morphometry by in vivo photographs in microscope, cell proliferation and apoptosis by immunohistochemistry, and exploratory behavior and phototropism by video recording. Our results showed an increase in embryo and larvae mortality in those exposed to 0.065 mg L−1, as well as a reduction in spontaneous embryo movements. The larval heartbeats showed a decrease at 4 dpf in the group exposed to 0.065 mg L−1 and an increase at 5 and 6 dpf in both exposed groups. Cell proliferation was reduced in both groups exposed in embryos and only in the 0.065 mg L−1 group in larvae, while cell death increased in embryos exposed to 6.5 mg L−1. These results demonstrated the toxic effect of low concentrations of the herbicide RWG® during embryonic and larval development of non target organisms, as well as the importance of constantly reviewing acceptable limits for exposure in natural environments.
Prevalence and temporal trend of gastric preneoplastic lesions in Asia: A systematic review with meta‐analysis
Authors: Li Yunhao , Jiang Fang , Wu Chun Ying , Leung Wai K. 
Published: December 2023

AbstractBackgroundGastric cancer is the fifth most common cancer globally, with about 75% of cases occurring in Asia. While chronic atrophic gastritis (CAG) and intestinal metaplasia (IM) are well‐recognized preneoplastic gastric lesions, we determined the prevalence and temporal trend of CAG and IM in Asia over the past 50 years.MethodsIn this systematic review and meta‐analysis, we searched PubMed, Embase, MEDLINE, Scopus, and Web of Science for studies reporting the prevalence of CAG and IM in Asia (according to the United Nations geoscheme) published between 1970 and 2022. Heterogeneity was assessed by the I2 index and Cochran Q test. We adopted the random effects model to estimate the pooled prevalence and 95% confidence interval (CI). The slope of prevalence was estimated as a function of time in simple linear regression and weighted meta‐regression models to demonstrate the temporal trend. Studies that reported the odds ratio (OR) of Helicobacter pylori infection and CAG/IM were analyzed separately to compile a pooled OR with a 95% CI. This study was registered in INPLASY2022120028.ResultsOf the 81 studies from 19 Asian countries identified, the pooled prevalence for CAG and IM in Asia was 26.1% (95%CI: 22.7–30.0) and 22.9% (95%CI: 19.7–26.6), respectively. Over the past 5 decades, there was a significant decline in the prevalence of IM (slope in adjusted meta‐regression models: −0.79 [95%CI: −1.28 to −0.26], P = 0.003), but there was no significant change in the pooled prevalence of CAG. Within Asia, the prevalence varied significantly among different regions. Southern Asia reported the highest pooled prevalence of CAG (42.9%, 95%CI: 27.5%–67.1%), while Western Asia reported the lowest level (12.7%, 95%CI: 5.0%–32.3%). For IM, Eastern Asia reported the highest prevalence (27.1%, 95%CI: 21.1–34.9), with the lowest prevalence reported in Western Asia (3.1%; 95% CI 1.2%–8.0%). H. pylori infection was linked to CAG and IM with OR of 2.16 (95%CI: 2.09–2.22) and 1.64 (95%CI: 1.57–1.72), respectively.ConclusionThis updated meta‐analysis showed that up to 26% of study individuals in Asia harbored preneoplastic gastric lesions. There was a declining temporal trend in the prevalence of IM, but not for CAG, in Asia.