bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparable use of tidal living shorelines and natural‐fringe marshes by herons and shorebirds
Authors: Leu Matthias , Isdell Robert E. , Galvin Robert M. , Rapp Andrew J. , Mason Samuel D. , Bilkovic Donna M. , Chambers Randolph M. 
Published: November 2023

AbstractLiving shorelines (LSs) increasingly are implemented as a defense against coastal erosion and rising seas; however, their ecological function for wading birds has not been evaluated. Here, we compared heron and shorebird use of LSs (created fringe salt marshes with a wave break fronting the planted marshes) to natural‐fringe marshes (NFMs) in the Chesapeake Bay. We assessed the use between May and August in 2018 and 2019 at 13 tidal marsh pairs, each consisting of one LS and NFM site, with sites within pairs having similar surrounding land use and wave exposure. In each year, we assessed diurnal use with video cameras recording at least four 30‐min segments/day for a total of 677 h of video, and nocturnal/diurnal use with acoustic recording equipment recording 10‐min sound files every 2 h/day for a total of 160 h of recording. We quantified diurnal use by measuring the total time a species spent at a site, and nocturnal/diurnal use by estimating the probability of detection (i.e., presence/absence). We detected four heron and five shorebird species when data were aggregated across pairs and sampling methods. Using Bayesian mixed models, time of use did not differ between LS and NFM sites for great blue herons (Ardea herodias) and yellow‐crowned night‐herons (Nyctanassa violacea). In contrast, time of use was higher for green herons (Butorides virescens) and spotted sandpipers (Actitis macularis) at LS sites but tended to be higher for great egrets (Ardea alba) at NFM sites. The probability of detection did not differ between LS and NFM sites for great blue herons and great egrets (combined as “Ardea spp.” due to difficulty in differentiating calls under noisy conditions), yellow‐crowned night‐herons, and spotted sandpipers. Green herons and killdeer (Charadrius vociferous), however, tended to be detected more frequently at LS sites. Collectively, our research indicates that LSs are functionally equivalent to NFMs for herons and shorebirds. We hypothesize that the low‐profile rock sills of LS provide platforms for resting and preening and offer prey even when vegetated marshes are unavailable to short‐legged species during flooding tides. In addition to their established reduction of coastal erosion, LSs provide habitat for herons and shorebird species.
Synthetic Outer Membrane Vesicles Bearing Tn Antigen
Authors: Chieffo Carolina , Comte Arnaud , Strazewski Peter , Fiore Michele 
Published: November 2023

AbstractN‐Alkyl‐thio glycolipids (TGL) are proposed as fundamental components in the production of synthetic outer membrane vesicles (S‐OMVs). A small but representative library of glycolipids was prepared by thiol‐ene coupling (TEC), using unprotected thiols in acceptable to good yields (63‐96 %). Multilamellar giant vesicles (GVs) of varying sizes were assembled from mixtures of TGL and 1‐palmitoyl‐2‐oleoyl‐sn‐glycero‐3‐phosphate (POPC). Our results mark an important advancement for the development of synthetic anticancer vaccines, supramolecular adjuvants and drug delivery systems based on glycolipid/phospholipid formulations (10 % mol/mol in 0.1 mm solution).
KA2 Coupling, Catalyzed by Well‐Defined NHC‐Coordinated Copper(I): Straightforward and Efficient Construction of α‐Tertiary Propargylamines**
Authors: Chalkidis Savvas G. , Vougioukalakis Georgios C. 
Published: November 2023

AbstractA new, straightforward, highly efficient, and mild catalytic protocol for the synthesis of α‐tertiary propargylamines, via the multicomponent KA2 reaction (Ketone‐Amine‐Alkyne), employing well‐defined, sustainable copper(I) complexes bearing N‐heterocyclic carbene ligands, is reported herein. The methodology uses very low catalyst loading under moderate heating to achieve the construction of a wide range of propargylamines in good to excellent yields in very short reaction times. Challenging substrates, including acyclic linear ketones, aromatic ketones, and electron‐poor aromatic alkynes, as well as substrates bearing synthetically valuable functionalities, are well tolerated.
Methanol as a C1 Source for the Synthesis of 1,3‐Polyheterocyclic Systems
Authors: Molteni Letizia , Beccalli Egle M. , Castoldi Laura , Broggini Gianluigi , Loro Camilla 
Published: November 2023

AbstractA very attractive approach toward 1,3‐polyheterocyclic systems was provided exploiting the copper‐catalyzed reaction of aminoalcohols and diaminoalkanes, in oxidative conditions and in the presence of methanol. The synthetic pathway showed the involvement of methanol both as solvent and as a reagent, making the procedure particularly efficient and sustainable for the synthesis of five‐, six‐, and seven‐membered polyheterocyclic rings.
Cobalt perchlorate hexahydrate catalyzed one‐pot synthesis of dihydropyrimidin‐ones/‐thiones through sonochemistry and its mechanistic study using density functional theory calculations
Authors: Ambatwar Ramesh , Kumar Sumit , Agarwal Dhairiya , Chandrakar Lokesh , Khatik Gopal L. 
Published: November 2023

AbstractA cobalt(II) perchlorate hexahydrate coordinated synthesis of dihydropyrimidin‐ones and ‐thiones through sonochemistry is developed. Herein, the reaction was demonstrated as a simple, efficient, and one‐pot method for synthesizing a series of interesting 3,4‐dihydropyrimidin‐2(1H)‐ones. Further, the reaction mechanism was investigated using mass spectrometry and density functional theory calculations suggesting that a Lewis acid character of cobalt(II) perchlorate hexahydrate plays a crucial role in coordinating carbonyl functionalities and stabilizing the polar intermediates like imine–enamine which further led to cyclized dihydropyrimidin‐ones and ‐thiones. This methodology was further explored to synthesize a gram‐scale synthesis of monastrol drug, a kinase inhibitor.
Cultivation and competition in Colombia: Disentangling the effects of coca price changes on violence
Authors: Stoelinga Nicole 
Published: November 2023

AbstractThough evidence indicates the presence of coca increases violence, changes to the price of coca products can have both negative and positive effects on conflict. This study addresses this matter. Using novel data on local prices of coca products, production and supply chains, this study disentangles the returns to employment in the agricultural sector (cultivators) and employment in the criminal sector (guerillas and paramilitaries). I identify each agents' respective exposure to price changes and estimate the effect of such changes on violence. The results show the presence of the opportunity cost effect: an increase in income from coca results in a reduction in violence. This reduction comes with an increase in school attendance for rural households. An increase in the objective prize (OP) leads to more violence. Moreover, guerillas flock to the area that witnesses such an increase, resulting in higher levels of competition which coincides with the timing of the increase in violence. Additionally, increasing expected returns to joining an armed group can lead to higher school dropout rates among children.
What are the impacts of climate change and the Ukrainian war on the sustainable development goals? A case study for Burkina Faso
Authors: Sawadogo Boureima , Maisonnave Hélène 
Published: November 2023

AbstractRepeated shocks to fragile economies call into question the feasibility of the achievement of the sustainable development goals. This study uses a gender‐dynamic computable general equilibrium model linked to a micro model to assess the impacts of the war in Ukraine and climate shocks on SDG1, SDG2, SDG5 and SDG8 for Burkina Faso's economy. The results reveal negative impacts on economic growth with an increase in food insecurity and household poverty. Urban households are the most affected by food insecurity, while unskilled men are most likely to lose their jobs in the short run. In the long run, however, women experience more job losses than men.
Medication error reporting attitudes and practices in a regional Australian hospital: a qualitative study
Authors: Abdelmaksoud Shady , Salahudeen Mohammed S. , Curtain Colin M. 
Published: November 2023

AbstractBackgroundMedication errors are events that may cause or lead to inappropriate medication use or patient harm. Australians living outside metropolitan areas have poorer health outcomes than those living in urban areas. Medication error reporting (MER) practices vary due to the attitude of healthcare professionals (HCPs). MER can improve patient safety in community and hospital settings.AimTo explore HCPs' attitudes, practices, and recommendations towards MER in a regional hospital setting in Australia.MethodSemistructured interviews were employed to identify the attitudes, practices, and recommendations of HCPs for the best utilisation of medication error reports. The study recruited HCPs (nurses, pharmacists, and doctors) working in all clinical areas from November 2021–February 2022. Interviews were recorded and transcribed via thematic analysis. Ethics approval was obtained from the Goulburn Valley Health (GVH) Human Research Ethics Committee (Reference no: GVH 35/21). Informed consent was obtained from participants via an information sheet and completion of a written consent form.ResultsInterviews with twelve HCPs elucidated four themes: barriers and enablers to reporting, and perceived benefits and recommendations for medication error reports. There was good understanding among regional HCPs about the benefits of MER. Attitudes and practices varied, with nurses reporting more medication errors than doctors, and pharmacists being concerned about the impact of reporting on interprofessional relations. Their recommendations involved standardising medication error definition and improving electronic system education.ConclusionDespite HCPs' understanding of the role of MER, their practices varied. We recommend improved protected time for learning, training with the incident reporting software, education about medication errors, and formalisation of test feedback to clinicians. The implementation of workplace cultural practice changes to improve organisational systems and enhance error reporting without fear of repercussions, and the adoption of additional solutions such as electronic prescribing are also encouraged.
Elastic Macroporous Matrix‐Supported In Situ Formation of Injectable Extracellular Matrix‐Like Hydrogel for Carrying Growth Factors and Living Cells
Authors: Abune Lidya , Wen Connie , Lee Kyungsene , Wang Xuelin , Ravnic Dino , Wang Yong 
Published: November 2023

AbstractHydrogels loaded with biologics hold great potential for various biomedical applications such as regenerative medicine. However, biologics may lose bioactivity during hydrogel preparation, shipping, and storage. While many injectable hydrogels do not have this issue, they face a dilemma between fast gelation causing the difficulty of injection and slow gelation causing the escape of solutions from an injection site. The purpose of this study is to develop an affinity hydrogel by integrating a pre‐formed elastic macroporous matrix and an injectable hydrogel. The data shows that the macroporous hydrogel matrix can hold a large volume of solutions for the formation of in situ injectable hydrogels loaded with growth factors or living cells. The cells can proliferate in the composite hydrogels. The growth factors can be stably sequestered and sustainably released due to the presence of aptamers. When both living cells and growth factors are loaded together into the hydrogels, cells can proliferate under culture conditions with a reduced serum level. Therefore, a macroporous and elastic matrix‐supported formation of aptamer‐functionalized injectable hydrogels is a promising method for developing the carriers of biologics.
Pricing and outsourcing strategies in different online sales models within a co‐opetitive supply chain
Authors: Shi Baoli , Xu Qi , Shan Renbang 
Published: November 2023

AbstractWe examine a dual‐tier supply chain where the brand entrusts its production to competitive and non‐competitive manufacturers. We explore three online sales models used by the brand and manufacturers: traditional, pre‐sale, and hybrid. Manufacturers serve the brand while competing with their own products. Considering consumer valuations across models, we create Stackelberg and Nash models. We analyze consumer valuation impact and the interplay of sales models and structural configurations on operational efficiency. We find that with competitive manufacturers' lower pricing, retailers tend to outsource to them. Retailers can choose sales models based on consumer evaluations, and higher dominance enhances profitability.
Bound‐preserving discontinuous Galerkin methods for compressible two‐phase flows in porous media
Authors: Sarraf Joshaghani Mohammad , Riviere Beatrice 
Published: November 2023

AbstractThis paper presents a numerical study of immiscible, compressible two‐phase flows in porous media, that takes into account heterogeneity, gravity, anisotropy and injection/production wells. We formulate a fully implicit stable discontinuous Galerkin solver for this system that is accurate, that respects maximum principle for the approximation of saturation, and that is locally mass conservative. To completely eliminate the overshoot and undershoot phenomena, we construct a flux limiter that produces bound‐preserving elementwise average of the saturation. The addition of a slope limiter allows to recover a pointwise bound‐preserving discrete saturation. Numerical results show that both maximum principle and monotonicity of the solution are satisfied. The proposed flux limiter does not impact the local mass error and the number of nonlinear solver iterations.
Predictive consensus tracking of multi‐agent systems in the presence of Byzantine agents and connection loss of reference signals
Authors: Rezaei Mohammad Amin , Bagheri Peyman , Hashemzadeh Farzad 
Published: November 2023

AbstractThis article proposes the consensus tracking of multi‐agent systems, in the presence of Byzantine agents and loss of connection between agents and the reference signal. The main purpose of this work is to steer a multi‐agent system to the desired reference, assuming that there are some agents which send incorrect information to the other agents, and the connection between the agents and the reference signal may lose. Using graph properties alongside the weighted‐mean‐subsequence‐reduced (W‐MSR) algorithm led to a novel control method for multi‐agent systems. With the aid of model predictive control (MPC), the agents reach the desired consensus with connection loss of reference signals, misbehaving agents in the system, and constraints on the input signals. Combining MPC with the W‐MSR algorithm results in an algorithm called reference‐based‐W‐MSR (RBW‐MSR), which has made the consensus point fixed according to a predetermined reference. A theorem is illustrated to guarantee the consensus with the interruption of reference signals and agents. The effectiveness of the proposed algorithm is illustrated via simulation results.
SSDraw: Software for generating comparative protein secondary structure diagrams
Authors: Chen Ethan A. , Porter Lauren L. 
Published: November 2023

AbstractThe program SSDraw generates publication‐quality protein secondary structure diagrams from three‐dimensional protein structures. To depict relationships between secondary structure and other protein features, diagrams can be colored by conservation score, B‐factor, or custom scoring. Diagrams of homologous proteins can be registered according to an input multiple sequence alignment. Linear visualization allows the user to stack registered diagrams, facilitating comparison of secondary structure and other properties among homologous proteins. SSDraw can be used to compare secondary structures of homologous proteins with both conserved and divergent folds. It can also generate one secondary structure diagram from an input protein structure of interest. The source code can be downloaded (https://github.com/ncbi/SSDraw) and run locally for rapid structure generation, while a Google Colab notebook allows easy use.
Genome‐scale metabolic models applied for human health and biopharmaceutical engineering
Authors: Li Feiran , Chen Yu , Gustafsson Johan , Wang Hao , Wang Yi , Zhang Chong , Xing Xinhui 
Published: November 2023

AbstractOver the last 15 years, genome‐scale metabolic models (GEMs) have been reconstructed for human and model animals, such as mouse and rat, to systematically understand metabolism, simulate multicellular or multi‐tissue interplay, understand human diseases, and guide cell factory design for biopharmaceutical protein production. Here, we describe how metabolic networks can be represented using stoichiometric matrices and well‐defined constraints for flux simulation. Then, we review the history of GEM development for quantitative understanding of Homo sapiens and other relevant animals, together with their applications. We describe how model develops from H. sapiens to other animals and from generic purpose to precise context‐specific simulation. The progress of GEMs for animals greatly expand our systematic understanding of metabolism in human and related animals. We discuss the difficulties and present perspectives on the GEM development and the quest to integrate more biological processes and omics data for future research and translation. We truly hope that this review can inspire new models developed for other mammalian organisms and generate new algorithms for integrating big data to conduct more in‐depth analysis to further make progress on human health and biopharmaceutical engineering.
Cholangiocellular adenoma in Franciscana dolphins (Pontoporia blainvillei)
Authors: Jerdy Hassan , Ribeiro Vanessa , Souza Aline , Valle Rodrigo , Maracini Pryscilla , Bertozzi Carolina , Hauser‐Davis Rachel Ann , Carvalho Eulógio 
Published: November 2023

AbstractPontoporia blainvillei, commonly known as the Franciscana dolphin, inhabits the coastal waters of South America and is classified as vulnerable and as undergoing significant population declines. This species is generally found in turbid coastal waters, although it is also found in clear waters, as well as marine areas associated with islands and rocky shores. Tumours originating from cholangiocytes have been rarely described in cetaceans, with descriptions limited to cholangiocellular carcinomas. Cholangiocellular adenomas are characterised by the formation of bile ducts and are rarer than cholangiocellular carcinoma. This study described the first report of a tumour originating from cholangiocytes in P. blainvillei, raising concerns on this endangered cetacean's health status and conservation. The underlying causes of this tumour in Franciscana dolphins remain unknown, highlighting the need for further research.
Two loop mass renormalisation in heterotic string theory: NS states
Authors: Bhattacharya Ritabrata 
Published: November 2023

Abstract
In this work computation of the renormalised mass at two loop order for the NS sector of heterotic string theory is attempted. We first implement the vertical integration prescription for choosing a section avoiding the spurious poles due to the presence of a required number of picture changing operators. As a result the relevant amplitude on genus 2 Riemann surface can be written as a boundary term. We then identify the 1PI region of the moduli space having chosen a gluing compatible local coordinates around the external punctures. We also identify the relevant integrands and the relevant region of integration for the modular parameters at the boundary.
Tachyons and Misaligned Supersymmetry in orientifold vacua
Authors: Leone Giorgio 
Published: November 2023

Abstract
We extend the analysis of Misaligned Supersymmetry to orientifold vacua. The lack of modular invariance in the Klein bottle, annulus and Möbius strip amplitudes implies that the IR properties of the physical spectrum are related to the UV behaviour of closed strings freely propagating between D-branes and O-planes, and vice versa. We thus build sector averaged sums 〈d(n)〉 associated to both representations of each Riemann surface. We find that the 〈d(n)〉’s associated to the loop channel control the coupling of closed-string tachyons to D-branes and/or O-planes, and therefore their vanishing is a necessary, but not sufficient, condition for stability in the closed sector. Similarly, the sector averaged sums associated to the tree-level amplitudes encode the presence of tachyons in the physical spectrum, and their vanishing is a sufficient, but not necessary, condition for classical stability. Using this technology, it is difficult, if not impossible, to formulate necessary and sufficient criteria for the absence of tachyons since, in orientifold vacua, they can be removed from the spectrum by the orientifold projection. Although in these cases one would naively expect a cancellation between 〈d(n)〉’s associated to different amplitudes, this does not occur in practice. We provide several examples in ten and lower dimensions supporting our results.