bluuebunny/crossref_metadata_2025_split huggingface dataset:
The place of comprehensive environmental and analytical assessment of the impact of the "CRE" system on environmental components in the EIA procedure
Authors: Adamova Hanna 
Published: February 2024

Problem. The operation of highways has a wide and multi-component impact on all components of the environment. Environmental Impact Assessment of roads is crucial for assessing the potential environmental consequences of road construction and operation. It is advisable to conduct this assessment based on a systemic analysis using a hierarchical structure for a comprehensive evaluation of the impact of the "CRE" system on the environment. Goal. The goal is to present the results of a comprehensive ecological-analytical assessment of the impact of roads on environment, which can be effectively used in the EIA procedure. Methodology. The 'CRE' system was analyzed using system analysis. Prioritization and weight coefficients for each element of the hierarchy were determined using expert-analytical assessments with the use of the MAI software complex. For a rapid assessment of the impact of road operation on the state of environment and the accumulation of heavy metals (HM) in vegetation and roadside soils, natural measurements and atomic absorption spectrometry methods were employed. Results. The expert-analytical research results revealed the contributions of each component within the complex hierarchical structure. Accumulation of HM in the roadside areas, including pollution of vegetation and soil, exceeding the permissible levels, was confirmed. Rank series were constructed: accumulation of HM in vegetation and soil samples, vegetation according to the property of accumulation of different HM in them. Originality. The study proposed a comprehensive assessment of the impact of road operation on the components of environment through an ecological-analytical evaluation of the developed hierarchical 'CRE' structure, resulting in the determination of weight coefficients and priorities of each element in the hierarchy's contribution to the environmental impact through expert-analytical assessment using the T. Saaty AНР method. Practical value. Using the proposed systematic approach in the EIA procedure for roads at every stage of their life cycle can improve control quality and the effectiveness of environmental protection measures, reducing environmental impact.
Pesan Dakwah Bil Qalam Ustadzah Halimah Alaydrus melalui Akun Instagram @Halimahalaydrus
Authors: Ramadhani Nurul Faizah 
Published: February 2024

<p>Instagram merupakan salah satunya, saat ini instagram menjadi salah satu media untuk berbagi dan mendapatkan informasi dalam berbagai jenis aspek dan bidang kehidupan, sehingga banyak <em>dai</em> dan <em>daiyah</em> yang memanfaatkan media instagram untuk berdakwah seperti halnya akun Instagram @halimahalaydrus yang menjadikan Instagram sebagai media dalam menyampaiakan pesan dakwah. Proses penelitian ini menggunakan pendekatan kualitatif. Pengumpulan data dalam penelitian dilakukan dengan observasi dan dokumentasi. Metode yang digunakan dalam penelitian adalah metode analisais isi (<em>content analysis</em>). Data primer diperoleh dari unggahan foto dalam akun @halimahalaydrus. Penelitian ini menggunakan teori kategori substansi pesan oleh Endan Saifuddin. Hasil penelitian menunjukan dari 19 sample foto dalam akun Instagram @halimahalaydrus yang menjadi objek penelitian ini terdapat 3 kategori pesan dakwah yang sudah dianalisis sesuai dengan teori yang dipakai, dimana 3 kategori tersebut yaitu: 1) Pesan dakwah Aqidah meliputi: iman kepada Rasul dan iman kepada Allah. 2) Pesan dakwah Syariah meluputi: berjihad, berdo’a dan bertawakal. 3) Pesan dakwah Akhlak meliputi: akhlak kepada sesama makhluk, lapang dada, bersyukur, melawan ego, sabar, menebar kasih sayang, tidak saling menyakiti, dan perbaikan/ intropeksi diri.</p><p> </p><p><em>Instagram is one of them, currently Instagram is one of the media for sharing and obtaining information in various types of aspects and fields of life, so that many preachers and daiyah utilize Instagram media for preaching, such as the Instagram account @halimahalaydrus which makes Instagram a medium in delivering da'wah messages. This research process uses a qualitative approach. Data collection in the study was carried out by observation and documentation. The method used in the research is the content analysis method. Primary data is obtained from photo uploads in the @halimahalaydrus account. This study uses the theory of message substance categories by Endan Saifuddin. The results showed that of the 19 sample photos in the @halimahalaydrus Instagram account which was the object of this research, there were 3 categories of da'wah messages that had been analyzed in accordance with the theory used, where the 3 categories were: 1) Aqidah da'wah messages include: faith in the Messenger and faith in Allah. 2) Sharia da'wah messages include: jihad, prayer and trust. 3) Moral da'wah messages include: morals to fellow creatures, spaciousness, gratitude, fighting ego, patience, spreading compassion, not hurting each other, and self-improvement / introspection.</em></p>
Bimbingan Belajar Olimpiade Sains Nasional (OSN) Matematika Siswa di SMPN 3 Batusangkar
Authors: Putri Jeni Tri , Alberianto Alberianto , Yuberta Kurnia Rahmi 
Published: February 2024

<p>The national mathematics science olympiads in junior high schools in the mathematics branch have an important role in the world of education by providing students with the ability to understand, apply and appreciate mathematical concepts in a scientific context. This includes developing a deeper understanding of mathematics, understanding of the scientific method, the ability to think logically, effective communication skills, and the ability to solve problems. This discussion details how the national science Olympiad helps students become individuals who are experts in mathematics and ready to play a role in science, technology and society.</p><p> </p>
The Oath-Taking (BAIAT) Phenomenon of Sampang Shia Become Sunni from A Human Rights Perspective
Authors: Muhlis Ahmad , Hannan Abd 
Published: February 2024

<p>This study discusses the integration of Sampang Shia followers into the Sunni sect from the Human Rights perspective. There are two formulations of the problem discussed in this study: what is the reality of the religious life of Sampang Shia adherents in Madura? Does the initiation of Shia Sampang contradict the principles of freedom of religion, especially the legal principles of human rights? This study uses a type of qualitative research. There are primary and secondary sources and data in this study. By using an analysis based on the perspective of legal sociology, this study found that Sampang Shia adherents experienced much unexpected problems such as intimidation, expulsion, and coercion to their religious life. Even though Sampang Shia adherents have taken allegiance to become Sunnis, they are still feeling worried and afraid. The stigma of being a former Shia adherent makes their existence and religious activities often come under scrutiny and suspicion. From the perspective of democracy in Indonesia, the series of events that have occurred in the religious life of the Shia followers of Sampang has violated the law, as contained in Article 28E paragraph (1) and Article 29 paragraph (2). Besides that, it is contrary to the principles of human rights, especially human rights principles at the personal level related to freedom of religion.</p><p><em>Studi ini fokus membahas fenomena pembaitan pengikut syiah Sampang ke dalam aliran Sunni ditinjau dari perspektif Hak Asasi Manusia (HAM). Terdapat dua rumusan masalah yang dibahas dalam kajian ini, bagaimana realitas kehidupan beragama penganut syiah Sampang di Madura? Adakah pembaitan Syiah Sampang bertentangan dengan prinsip kebebasan beragama, terkhusus prinsip hukum Hak Asasi Manusia? Studi ini menggunakan jenis penelitian kualitatif. Sumber dan jenis data dalam penelitian ini terdiri dari dua, primer dan sekunder. Dengan menggunakan analisa berdasarkan perspektif sosiologi hukum, studi ini mendapati temuan bahwa realitas kehidupan beragama muslim syiah Sampang Madura mengalami banyak perlakuan negatif seperti intimidasi, pengusiran, dan pemaksaan. Bahkan meski sudah melakukan baiat diri menjadi Sunni, mereka (Syiah Sampang) masih dilanda rasa kekhawatiran dan ketakutan. Stigma sebagai eks penganut Syiah membuat keberadaan dan aktivitas beragama mereka sering kali mendapat sorotan dan kecurigaan. Dalam perspektif demokrasi di Indonesia, rangkaian pristiwa yang menimpa khidupan beragama penganut syiah Sampang bukan saja telah melanggar perundangan, sebagaimana termuat alam pasal 28E ayat (1) dan Pasal 29 Ayat (2). Lebih dari itu, juga bertentangan dengan prinsip Hak Asasi Manusia (HAM), khususnya prinsip HAM di level personal yang terkait dengan kebebasan beragama.</em></p>
Implementasi Manajemen Mutu Pendidikan di Madrasah Tsanawiyah Negeri 2 Kota Malang
Authors: Widodo Wahyudi 
Published: February 2024

Madrasah berada dalam kondisi permasalahan yang bersifat saling berhubungan satu sama lain, meliputi dana yang kurang memadai, fasilitas kurang, guru seadanya dan mengajar di lebih dari satu sekolah, kualitas rendah, kurang bersemangat, inovasi rendah, dan rendahnya peminat. Madrasah belum memiliki penjamin mutu internal. Penelitian ini bertujuan untuk mengungkap implementasi manajemen mutu di Madrasah Tsanawiyah Negeri 2 Kota Malang. Metode penelitian menggunakan pendekatan deskriptif kualitatif yaitu mendeskripsikan fenomena dalam pelaksanaan mutu di madrasah swasta. Teknik pengumpulan data menggunakan studi wawancara bersama kepala madrasah, wakil kepala madrasah dan pendidik; studi dokumentasi berkaitan dengan dokumen yang terkait dengan 8 standar di madrasah; studi observasi yaitu pelaksanaan mutu, penjaminan mutu di internal madrasah. Hasil penelitian menunjukan bahwa rendahnya mutu pendidikan di madrasah tersebut berdampak dari pembiayaan madrasah yang masih belum memiliki kemandirian finansial, madrasah masih bertumpu pada bantuan operasional madrasah dan biaya bulanan dari siswa. Agenda penjaminan mutu akademik dilaksanakan secara maksimal oleh sivitas akademik madrasah.
Bioinformatics analysis of markers based on m6A related to prognosis combined with immune invasion of rectal adenocarcinoma
Authors: Yan Shunkang , Zhang Jiandong , Li Lianghe , Chen Gang , Chen Zhongsheng , Zhan Wei 
Published: February 2024

BACKGROUND: Colorectal cancer (CRC) is a common form of cancer, with rectal cancer accounting for approximately one-third of all cases. Among rectal cancers, 95% are classified as rectal adenocarcinoma (READ). Emerging evidence suggests that long noncoding RNAs (lncRNAs) play a significant role in the development and progression of various cancers. In our study, we aimed to identify differentially expressed lncRNAs potentially associated with m6A and establish a risk assessment model to predict clinical outcomes for READ patients. METHODS: The READ dataset from the TCGA database was utilized in this study to synergistically and logically integrate m6A and lncRNA, while employing bioinformatics technology for the identification of suitable biomarkers. A risk prediction model comprising m6A-associated lncRNAs was constructed to investigate the prognostic, diagnostic, and biological functional relevance of these m6A-related lncRNAs. RESULTS: Our research builds a composed of three related to m6A lncRNA rectal gland cancer prognosis model, and the model has been proved in the multi-dimensional can serve as the potential of the prognosis of rectal gland cancer biomarkers. Our study constructed a prognostic model of rectal adenocarcinoma consisting of three related m6A lncRNAs: linc00702, ac106900.1 and al583785.1. CONCLUSION: The model has been validated as a potential prognostic biomarker for rectal cancer in multiple dimensions, aiming to provide clinicians with an indicator to assess the duration of straight adenocarcinoma. This enables early detection of rectal cancer and offers a promising target for immunotherapy.
Deep hybrid classification model for leaf disease classification of underground crops
Authors: Salini R. , Charlyn Pushpa Latha G. , Khilar Rashmita 
Published: February 2024

Underground crop leave disease classification is the most significant area in the agriculture sector as they are the significant source of carbohydrates for human food. However, a disease-ridden plant could threaten the availability of food for millions of people. Researchers tried to use computer vision (CV) to develop an image classification algorithm that might warn farmers by clicking the images of plant’s leaves to find if the crop is diseased or not. This work develops anew DHCLDC model for underground crop leave disease classification that considers the plants like cassava, potato and groundnut. Here, preprocessing is done by employing median filter, followed by segmentation using Improved U-net (U-Net with nested convolutional block). Further, the features extracted comprise of color features, shape features and improved multi text on (MT) features. Finally, Hybrid classifier (HC) model is developed for DHCLDC, which comprised CNN and LSTM models. The outputs from HC(CNN + LSTM) are then given for improved score level fusion (SLF) from which final detected e are attained. Finally, simulations are done with 3 datasets to show the betterment of HC (CNN + LSTM) based DHCLDC model. The specificity of HC (CNN + LSTM) is high, at 95.41, compared to DBN, NN, RF, KNN, CNN, LSTM, DCNN, and SVM.
Accessibility and Affordability Impacts of Half Price Public Transport Fares in Aotearoa New Zealand
Authors: Curl Angela , Coppens Anna , Dares Cushla , Williman Jonathan , Fitt Helen , Kingham Simon 
Published: February 2024

Transport costs can constitute a large proportion of household budgets and restrict travel. Reduced or free public transport fares are one strategy to address these affordability and accessibility challenges. We analyse data from a 2022 transport survey to investigate participants perspectives and experiences of half price public transport fares in Ōtautahi Christchurch, a city in Aotearoa New Zealand. We find that those experiencing transport poverty are likely to have benefitted in terms of widening access and reduced financial stress.
HPLC-UV Analysis of Flavonoid Glycosides in the Herb of <i>Astragalus</i> (<i>A. dasyanthus</i>, <i>A. varius</i>, <i>A. testiculatus</i>, <i>A. henningii</i>), Growing in the Volga Region
Authors: Matvienko U. A. , Durnova N. A. , Poluyanov A. M. , Bobkova N. V. , Ramenskaya G. V. 
Published: February 2024

Introduction. The search for new promising sources of biologically active substances is one of the tasks of modern pharmacognosy. Among the huge variety of species of the genus Astragalus L., only a few of them have been studied. In addition, none of them is included in the current edition of the State Pharmacopoeia of the Russian Federation. In our opinion, the study of four species of this genus of Astragalus L. (A. dasyanthus, A. varius, A. testiculatus, A. henningii) growing in the Volga region is of interest.Aim. Study of the glycoside composition of flavonoids in the astragalus herb of four species (A. dasyanthus, A. varius, A. testiculatus, A. henningii) by HPLC-UV using external standards.Materials and methods. The material was samples of astragalus grass (A. dasyanthus, A. varius, A. testiculatus, A. henningii), collected on the territory of the Saratov region in accordance with the basic rules of collection and preparation and dried to an air-dry state. Aqueous-alcoholic extracts (1 : 50) were analyzed. Qualitative and quantitative analysis of flavonoid glycosides was carried out on an Agilent 1260 chromatograph (Agilent Technologies, USA) equipped with a diode array detector, manual sample injection (Agilent G1328C manual injector, Agilent Technologies USA) and an Agilent Open Lab CDS system for collecting and processing chromatographic data. The elution gradient was selected individually using 0.1 % phosphoric acid/acetonitrile solution as solvents. Compounds were identified by retention times and UV spectra of reference standards (RS). The quantitative content of each detected component was expressed in mg/g of dry raw material. All studies were repeated five times, the results were statistically processed using MS Exсel 2010.Results and discussion. The chromatographic profiles of aqueous-alcoholic extracts from the herbs of four types of astragalus were studied. Differences were found in both the qualitative composition and quantitative content of flavonoid glycosides in the grass of the analyzed species. The largest number of compounds was found in the herb of A. varius (6 compounds), 4 compounds were identified in the herb of A. dasyanthus and A. henningii, and 3 compounds were identified in the herb of A. testiculatus. The dominant components in the herb of A. henningii are orientin and rutin, in the herb of A. testiculatus and A. varius it is cynaroside, and in A. dasyanthus it is rutin.Conclusion. A HPLC-UV method was developed for determining the quantitative content of flavonoid glycosides in extracts from the herbs of four species of astragalus (A. dasyanthus, A. varius, A. testiculatus, A. henningii) and the chromatographic profiles of the analyzed samples were studied.
Evaluate the effects of low-intensity pulsed ultrasound on dental implant osseointegration under type II diabetes
Authors: Wang Yingying , Cao Ximeng , Shen Yingyi , Zhong Qi , Wu Ziang , Wu Yaqin , Weng Weimin , Xu Chun 
Published: February 2024

Objective: The objective of this study is to assess the impact of low-intensity pulsed ultrasound (LIPUS) therapy on the peri-implant osteogenesis in a Type II diabetes mellitus (T2DM) rat model.Methods: A total of twenty male Sprague-Dawley (SD) rats were randomly allocated into four groups: Control group, T2DM group, Control-LIPUS group, and T2DM-LIPUS group. Implants were placed at the rats’ bilateral maxillary first molar sites. The LIPUS treatment was carried out on the rats in Control-LIPUS group and T2DM-LIPUS group, immediately after the placement of the implants, over three consecutive weeks. Three weeks after implantation, the rats’ maxillae were extracted for micro-CT, removal torque value (RTV), and histologic analysis.Results: Micro-CT analysis showed that T2DM rats experienced more bone loss around implant cervical margins compared with the non-T2DM rats, while the LIPUS treated T2DM rats showed similar bone heights to the non-T2DM rats. Bone-implant contact ratio (BIC) were lower in T2DM rats but significantly improved in the LIPUS treated T2DM rats. Bone formation parameters including bone volume fraction (BV/TV), trabecular thickness (Tb.Th), bone mineral density (BMD) and RTV were all positively influenced by LIPUS treatment. Histological staining further confirmed LIPUS’s positive effects on peri-implant new bone formation in T2DM rats.Conclusion: As an effective and safe treatment in promoting osteogenesis, LIPUS has a great potential for T2DM patients to attain improved peri-implant osteogenesis. To confirm its clinical efficacy and to explore the underlying mechanism, further prospective cohort studies or randomized controlled trials are needed in the future.
Therian origin of INSL3/RXFP2-driven testicular descent in mammals
Authors: Menzies Brandon R. , Tarulli Gerard A. , Frankenberg Stephen R. , Pask Andrew J. 
Published: February 2024

Introduction: During early development in most male mammals the testes move from a position near the kidneys through the abdomen to eventually reside in the scrotum. The transabdominal phase of this migration is driven by insulin-like peptide 3 (INSL3) which stimulates growth of the gubernaculum, a key ligament connecting the testes with the abdominal wall. While all marsupials, except the marsupial mole (Notoryctes typhlops), have a scrotum and fully descended testes, it is unclear if INSL3 drives this process in marsupials especially given that marsupials have a different mechanism of scrotum determination and position relative to the phallus compared to eutherian mammals.Methods: To understand if INSL3 plays a role in marsupial testicular descent we have sequenced and curated the INSL3 gene and its receptor (RXFP2) in a range of marsupials representing every order. Furthermore, we looked at single cell RNA-seq and qPCR analysis of INSL3 in the fat-tailed dunnart testis (Sminthopsis crassicaudata) to understand the location and timing of expression during development.Results: These data show a strong phylogenetic similarity between marsupial and eutherian orthologues, but not with monotreme INSL3s which were more similar to the ancestral RLN3 gene. We have also shown the genomic location of INSL3, and surrounding genes is conserved in a range of marsupials and eutherians. Single cell RNA-seq and qPCR data show that INSL3 mRNA is expressed specifically in Leydig cells and expressed at higher levels during the testicular descent phase in developing marsupials.Discussion: Together, these data argue strongly for a therian origin of INSL3 mediated testicular descent in mammals and suggests that a coordinated movement of the testes to the abdominal wall may have preceded externalization in marsupials and therian mammals.
Mitochondrial dysfunction and therapeutic perspectives in osteoporosis
Authors: Liu Jialing , Gao Zhonghua , Liu Xiangjie 
Published: February 2024

Osteoporosis (OP) is a systemic skeletal disorder characterized by reduced bone mass and structural deterioration of bone tissue, resulting in heightened vulnerability to fractures due to increased bone fragility. This condition primarily arises from an imbalance between the processes of bone resorption and formation. Mitochondrial dysfunction has been reported to potentially constitute one of the most crucial mechanisms influencing the pathogenesis of osteoporosis. In essence, mitochondria play a crucial role in maintaining the delicate equilibrium between bone formation and resorption, thereby ensuring optimal skeletal health. Nevertheless, disruption of this delicate balance can arise as a consequence of mitochondrial dysfunction. In dysfunctional mitochondria, the mitochondrial electron transport chain (ETC) becomes uncoupled, resulting in reduced ATP synthesis and increased generation of reactive oxygen species (ROS). Reinforcement of mitochondrial dysfunction is further exacerbated by the accumulation of aberrant mitochondria. In this review, we investigated and analyzed the correlation between mitochondrial dysfunction, encompassing mitochondrial DNA (mtDNA) alterations, oxidative phosphorylation (OXPHOS) impairment, mitophagy dysregulation, defects in mitochondrial biogenesis and dynamics, as well as excessive ROS accumulation, with regards to OP (Figure 1). Furthermore, we explore prospective strategies currently available for modulating mitochondria to ameliorate osteoporosis. Undoubtedly, certain therapeutic strategies still require further investigation to ensure their safety and efficacy as clinical treatments. However, from a mitochondrial perspective, the potential for establishing effective and safe therapeutic approaches for osteoporosis appears promising.