bluuebunny/crossref_metadata_2025_split huggingface dataset:
Use of small stents for rehabilitation of hypoplastic pulmonary arteries in pulmonary atresia with ventricular septal defect
Authors: Vranicar Mark , Teitel David F. , Moore Phillip 
Published: August 2002

AbstractBranch pulmonary artery stenosis frequently occurs in pulmonary atresia with ventricular septal defect (PA/VSD). Balloon dilation alone is often unsuccessful in patients with severely hypoplastic pulmonary arteries with residual stenoses after surgical repair. In an attempt to promote distal pulmonary artery growth, 17 stents were placed in 12 severely stenotic pulmonary artery lesions in 10 patients with PA/VSD. All had prior surgery, including pulmonary artery repair, right ventricle to pulmonary artery homograft, and, in 6 of 10, closure of VSD. Median age at stent placement was 16.8 months (range, 13.2–56). Stents were placed using 3.0, 3.5, or 4.0 mm balloons in all but one lesion, in which a 7 mm balloon was used. Following stent placement, there was an increase in the lesion diameter from 1.5 to 3.4 mm (P < 0.05) and an increase in flow to the affected lung from 27% to 34% (P < 0.05). Repeat catheterization 2 to 6 months after stenting in six patients revealed complete occlusion in two of eight lesions. In the other six vessels, there was an increase in distal vessel diameter from 2.96 to 3.94 mm (P < 0.05) even though four had severe restenosis requiring restenting. Two patients underwent surgical pulmonary artery reconstruction and stent removal because of adequate distal vessel growth. Stenting of hypoplastic pulmonary arteries in PA/VSD results in immediate improvement in vessel size and blood flow. Stent restenosis is common although distal vessel growth can be achieved. Stenting of these lesions should be reserved only for those patients unresponsive to other interventions. Cathet Cardiovasc Intervent 2002;55:78–82. © 2002 Wiley‐Liss, Inc.
Intracoronary beta‐radiation of de novo coronary lesions using a 186Re liquid‐filled balloon system: Six‐month results from a clinical feasibility study
Authors: Coussement Patrick K. , Stella Pieter , Vanbilloen Hubert , Verbruggen Alfons , van Rijk Peter , Hoekstra A. , Van Limbergen Erik , de Jaegere Peter , De Scheerder Ivan 
Published: August 2002

AbstractVascular brachytherapy has shown to be effective for in‐stent restenosis, but efficacy in de novo lesions remains uncertain. We evaluated feasibility and outcome of intracoronary beta‐radiation therapy in de novo coronary lesions using a 186Re liquid‐filled balloon system. Thirty‐three patients received 20 Gy 186Re beta‐radiation immediately after balloon angioplasty. The 6‐month restenosis rate was 41% (12/29) and restenosis was located within the target lesion in eight patients and at the edges of the injured and irradiated segment, outside the target lesion, in four patients. At 6 months, four patients (12%), all stented during the initial procedure, had experienced a late (> 30 days) total occlusion. Intracoronary beta‐radiation therapy of de novo coronary lesions using 186Re is technically feasible. No reduction in restenosis was observed. The high incidence of late total occlusions may have been prevented by avoiding new stent implantation and prolonging double antiplatelet therapy. Cathet Cardiovasc Intervent 2002;55:28–36. © 2002 Wiley‐Liss, Inc.
Closure of an iatrogenic aortocoronary arteriovenous fistula: Transcatheter balloon embolization following failed coil embolization and salvage of coils that migrated into the coronary venous system
Authors: Maier Lars S. , Buchwald Arnd B. , Ehlers Björn , Rühmkorf Klaus , Scholz Karl H. 
Published: August 2002

AbstractWe report a 50‐year‐old patient with successful percutaneous closure of a large inadvertent surgical aortocoronary arteriovenous fistula (shunt flow: 1.8 L/min). With initial embolization of multiple coils, no lasting occlusion of the large fistula could be achieved. Above that, two coils migrated into the coronary venous system. Following rescue of the migrated coils through a retrograde coronary sinus approach, the fistula was occluded using a detachable balloon. Follow‐up angiograms confirmed successful closure of the fistula. In contrast to coil embolization, use of a detachable balloon seems to be the appropriate technique for percutaneous closure of such fistulas. Cathet Cardiovasc Intervent 2002;55:109–112. © 2002 Wiley‐Liss, Inc.
Use of a 0.052″ Gianturco coil to embolize a persistent right superior vena cava following extracardiac total cavopulmonary connection
Authors: Tomita Hideshi , Ishikawa Yuichi , Hasegawa Satoshi , Ono Yasuo , Yamada Osamu , Kimura Kohji , Uemura Hideki , Yagihara Toshikatsu , Echigo Shigeyuki 
Published: August 2002

AbstractA persistent right superior vena following extracardiac total cavopulmonary connection was occluded using a 0.052″ Gianturco coil combined with a 3 Fr biopsy forceps. Controlled delivery of a 0.052″ Gianturco coil is a safe and effective procedure to occlude a large anomalous vessel other than a large persistent arterial duct. Cathet Cardiovasc Intervent 2001;52:481–483. © 2001 Wiley‐Liss, Inc.
An unusual case of groin discomfort
Authors: Tuli Ajay , Lim Sung S. , Zafari A. Maziar 
Published: August 2002

AbstractGroin complications after cardiac catheterizations are common. With the increasing use of mechanical hemostatic devices, cardiologists must be alert to a wide array of potential problems. We report an unusual complication after the use of a closure device. Cathet Cardiovasc Intervent 2001;52:484–485. © 2001 Wiley‐Liss, Inc.
Successful stenting of a complex inferior vena cava stenosis using a modified sharp recanulization technique
Authors: Patel Tejas , Shah Sanjay , Sanghvi Kintur , Fonseca Keith 
Published: August 2002

AbstractWe describe a case of a 30‐year‐old male who presented with features of noncirrhotic portal hypertension, who was diagnosed to have inferior vena cava (IVC) obstruction. IVC angiogram and ultrasound study revealed a long‐segment (36 mm long), chronic total thrombotic occlusion that was dilated and stented with a satisfactory end result. The unique feature of this case is a modified sharp recanulization technique involving the use of Brokenborough (septal puncture) needle and Mullin dilator to create a track in such a long, chronic total occlusion under simultaneous ultrasound and fluoroscopic guidance. Cathet Cardiovasc Intervent 2001;52:492–495. © 2001 Wiley‐Liss, Inc.
Laser angioplasty in a right coronary artery stent restenosis with the guidance of left internal mammary artery contrast injection: Case report
Authors: Okmen Ertan , Cakmak Mahmut , Celik Seden , Yapici Fikri , Erdinler Izzet , Ozturk Recep , Cam Nese 
Published: August 2002

AbstractA 43‐years‐old male who underwent right coronary artery stent implantation 6 months ago presented with total occlusion of right coronary artery at proximal part of the stent without antegrade flow. We successfully used the left internal mammary artery contrast injections for guidance in all stages of the right coronary laser angioplasty intervention. Cathet Cardiovasc Intervent 2001;53:71–74. © 2001 Wiley‐Liss, Inc.
Noninvasive detection of coronary lesions by multislice computed tomography: Results of the new age pilot trial
Authors: Schroeder Stephen , Kopp Andreas F. , Baumbach Andreas , Kuettner Axel , Herdeg Christian , Rosenberger Albert , Selbmann Hans‐K. , Claussen Claus D. , Oberhoff Martin , Karsch Karl R. 
Published: August 2002

AbstractThe reliable noninvasive assessment of coronary artery disease would constitute an important step forward in clinical cardiology. The aim of the New Age pilot trial was to evaluate the diagnostic accuracy of multislice computed tomography (MSCT) in determining coronary lesions. As a gold standard for in vivo plaque detection, intracoronary ultrasound (ICUS) was used. Forty plaques were detected by ICUS in 15 target vessels (LAD, n = 8; RCA, n = 7) in patients assigned for ICUS‐guided PTCA. Preinterventional MSCT was performed in all patients and the results were compared to ICUS with regard to lesion detection and quantification. According to ICUS results, the 40 plaques were divided into three groups: group I, mild lesions < 50% (n = 14; 44.36% ± 5.77%); group II, intermediate lesions 50%–75% (n = 12; 59.18% ± 9.39%); and group III, severe lesions > 75% (n = 14; 91.47% ± 3.68%). All MSCT scans showed sufficient image quality for analysis. Thirty of 40 (75%) plaques were detected by MSCT in a first blinded session. After unblinding the ICUS results, the remaining 10 (25%) plaques could be identified. Lesion severity was classified correctly in 34 of 40 (85%) plaques. Plaque calcifications were diagnosed correctly in 16 of 19 (84.2%) plaques. Quantification of vessel size revealed a good correlation to the ICUS results (r2 0.68; P = 0.004). Noninvasive MSCT angiography showed good diagnostic accuracy with regard to lesion detection and quantification of vessel size. The overall good image quality, makes this new technology a promising modality, which might become an alternative diagnostic approach in patients with known or suspected coronary artery disease. Cathet Cardiovasc Intervent 2001;53:352–358. © 2001 Wiley‐Liss, Inc.
Percutaneous transluminal alcohol septal myocardial ablation after aortic valve replacement
Authors: Sitges Marta , Kapadia Samir , Rubin David N. , Thomas James D. , Tuzcu Murat E. , Lever Harry M. 
Published: August 2002

AbstractWhen left ventricular outflow tract obstruction develops after aortic valve replacement, few treatment choices have been available until now. We present a patient with prior aortic valve replacement who developed left ventricle outflow tract obstruction that was successfully treated with a percutaneous transcoronary myocardial septal alcohol ablation. This technique is a useful tool for the treatment of obstructive hypertrophic cardiomyopathy, especially in those patients with prior heart surgery. Cathet Cardiovasc Intervent 2001;53:524–526. © 2001 Wiley‐Liss, Inc.
Acute symptomatic hyponatremia complicating invasive cardiac procedures: A report of three patients
Authors: Boulos Monther , Nakhoul Farid , Hir Jamal , Markiewicz Walter 
Published: August 2002

AbstractHyponatremic encephalopathy is a well‐known complication of surgical procedures. This syndrome has not been described in the cardiology literature. We report three patients who developed acute hyponatremia with life‐threatening encephalopathy following an invasive cardiac procedure. Diagnosis and treatment were delayed because of a lack of awareness for the syndrome among the cardiology staff. The diagnosis of hyponatremia should be suspected in any patient who develops behavioral or neurological manifestations following an invasive cardiac procedure. Prompt diagnosis and treatment are essential to avoid permanent neurological damage or death. Cathet Cardiovasc Intervent 2001;53:542–545. © 2001 Wiley‐Liss, Inc.
A comparison of total hospital costs for percutaneous coronary intervention patients receiving abciximab versus tirofiban
Authors: McCollam Patrick L. , Lage Maureen J. , Bala Mohan 
Published: August 2002

AbstractThe purpose of this study was to examine the total hospital costs associated with the receipt of abciximab versus tirofiban for percutaneous coronary intervention (PCI) patients. Hospital billing data for patients with a primary procedure of PCI was examined for the period of July 1998 to June 1999 from HCIA‐Sach's Clinical Pathways Database. Data were analyzed for all patient discharges whose records indicated use of abciximab or tirofiban with a PCI. Results are reported for 3,967 patients. Multivariate analysis was used to control for a wide range of factors (GP IIb/IIIa selection, patient demographics, stent use, insurance type, health conditions, admission information, and hospital characteristics) that may influence the cost of hospitalization. A two‐stage sample selection model was used to estimate total costs. The first stage of the analysis utilizes a probit regression to determine the factors associated with the likelihood of receiving abciximab versus tirofiban. The second stage of the analysis examines the factors associated with total hospital costs, while controlling for unobserved factors that may be correlated with the patient's likelihood of receiving abciximab. The mean unadjusted cost per hospitalization, including drug costs, was $10,762 (abciximab $10,813 and tirofiban $10,567). After controlling for high‐risk indications and selection bias with the two‐stage sample selection model, results indicate there was no significant difference in costs associated with the receipt of abciximab versus tirofiban. However, the results also indicate that the two‐stage sample selection model may not be needed (λ was not statistically significant) hence, the cost equation was reestimated using ordinary least‐squares methodology (OLS). In the OLS analysis, receipt of abciximab versus tirofiban was associated with a significant reduction in costs ($470 reduction; P = 0.05). This study uses real‐world data to examine the total hospital costs for PCI patients who receive abciximab versus tirofiban. Results of the two‐stage sample selection model indicate there is no difference in total hospital costs (including drug costs) between abciximab‐ and tirofiban‐treated patients. If the results of the OLS model are considered, a slight decrease in total hospital costs is observed in abciximab recipients. Cost‐containment strategies that focus on component costs may not lead to intended overall cost savings. Cathet Cardiovasc Intervent 2001;54:152–157. © 2001 Wiley‐Liss, Inc.
Activated clotting time as a screening test prior to catheter‐based cardiovascular procedures
Authors: Siskin Gary P. , Reiner Eric , Stainken Brian F. , Dowling Kyran , Dolen Eric G. , Quarfordt Steven , Albons Gom 
Published: August 2002

AbstractThe activated clotting time (ACT) was investigated as a rapid, inexpensive, point‐of‐service screening test for coagulation abnormalities prior to catheter‐based procedures. A total of 963 patients were screened by obtaining a history, standard coagulation profile, and activated coagulation time. The prevalence of normal patients (normal ACT and coagulation profile) was 94% (sensitivity = 91%; specificity = 27%). A normal ACT had a positive predictive value of 95%. The ACT was an acceptable screening test due to its ability to predict positively a low rate of bleeding complication and normal coagulation studies. Patients with ACT > 150 sec should be further evaluated with a screening coagulation panel. Additionally, given its low specificity, coagulation studies should be obtained in high‐risk patients since an abnormal ACT does not effectively correlate with abnormal coagulation studies. Cathet Cardiovasc Intervent 2001;54:191–195. © 2001 Wiley‐Liss, Inc.
Successful closure of coronary artery perforation using makeshift stent sandwich
Authors: PienvichitMD Pavit , Waters James 
Published: August 2002

AbstractAn elderly woman underwent stenting of mid left anterior descending coronary artery (LAD) 2 days after myocardial infarction. During high‐pressure stent dilatation, vessel perforation was noted. We assembled a “stent sandwich” in the cardiac catheterization laboratory and used it successfully to seal the perforation with good angiographic result. Although the long‐term patency remains an issue, this case demonstrates the feasibility of using makeshift covered‐stent as a bailout for arterial perforation in selected cases where emergency thoracotomy is undesirable. Cathet Cardiovasc Intervent 2001;54:209–213. © 2001 Wiley‐Liss, Inc.
Ernest L. Eliel: A life of purpose, determination, and integrity
Authors: Seeman Jeffrey I. 
Published: August 2002

AbstractA concise biography of Ernest L. Eliel is presented. The highlights of Eliel's scientific achievements are described, beginning with his Ph.D. thesis research performed under the supervision of Professor Harold Snyder (University of Illinois) and continuing as a faculty member at Notre Dame (synthesis of nonracemic C6H5CHDCH3; kinetic method of conformational analysis; equilibrium and NMR methods of conformational analysis); and at the University of North Carolina (conformational analysis of heterocyclic compounds; enantioselective synthesis). Eliel's professional career as a teacher, textbook author, and major figure in the American Chemical Society are discussed. His philosophies of life, science, and chemistry are described by a series of poignant quotations. Chirality 14:98–109, 2002. © 2002 Wiley‐Liss, Inc.
Stereospecific cleavage of carbon‐phosphorus bonds: Stereochemical course of the phosphinoyl curtius (harger) reaction
Authors: Denmark Scott E. , Dorow Roberta L. 
Published: August 2002

AbstractThe homochiral phosphinic azides (R,R)‐1 and (S,S)‐1 were prepared in enantiomerically pure form by resolution of diastereomeric phosphinamides derived from (S)‐l‐phenylethylamine and (R)‐phenylglycine. Irradiation of the azides in methanol induced a photo‐Curtius rearrangement to phosphonamidates in which the stereogenic carbon unit migrated to a nitrogen atom. Hydrolysis of the phosphonamidates produced 1‐phenylethylamine, which was 99.0% e.e. and of the same configuration as the carbon unit in the starting azide (99.0% retention). Chirality 14:241–257, 2002.© 2002 Wiley‐Liss, Inc.
Regioselective and stereoselective cleavage of cis‐4‐methyl‐2‐vinyl‐l,3‐dioxane by alkyllithiums
Authors: Bailey William F. , Zarcone Lyn M.J. 
Published: August 2002

AbstractThe reaction of alkyllithiums with cis‐4‐methyl‐2‐vinyl‐1,3‐dioxane proceeds in virtually quantitative yield via a formal SN2′ ring opening that proceeds in a regioselective manner to give preferential cleavage of the C(2)–O(l) bond remote from the 4‐methyl substituent, affording the E‐enol ether as the major stereoisomer. A two‐step mechanism, involving addition of the alkyllithium followed by syn‐elimination of lithium alkoxide, is suggested to account for the stereochemical outcome. Chirality 14:163–165, 2002.© 2002 Wiley‐Liss, Inc.
An NMR investigation of the conformational equilibria of 2‐(2′‐pyridyl)ethylphosphonic acid in several solvents
Authors: Petterson Krag A. , Fort Diana , Wei Peter D. , Roberts John D. 
Published: August 2002

AbstractVicinal proton–proton NMR couplings have been used to investigate whether the position of conformational equilibria is determined by intramolecular N‐H hydrogen bonding for 2‐(2′‐pyridyl)ethylphosphonic acid 1 in its various possible ionization states in water, methanol, ethanol, and dimethyl sulfoxide (DMSO). With 1 in the form of its monoanion and dianion, the trans is favored, with the dianion being more trans than the monoanion for a given solvent, probably as the result of steric effects, possibly enhanced by repulsive electrostatic effects between the negatively charged phosphonic group and the lone pair on the pyridine nitrogen. For 1 and its conjugate acid, the gauche amounts, respectively, to 43% and 45% in water, 66% and 51% in methanol, 66% and 64% in ethanol, and 29% and 49% in DMSO. For these latter two species, electrostatic, steric, and hydrogen bonding‐effects are all likely to play a role in determining the conformational equilibria. Chirality 14:204–208, 2002. © 2002 Wiley‐Liss, Inc.
Hydrobenzoin‐based rigid chiral polymer
Authors: Bieging Anna , Liao Li‐Xin , McGrath Dominic V. 
Published: August 2002

AbstractWe prepared a rigid, chiral polymer (1) from optically active hydrobenzoin‐based subunits. Nonracemic monomer units 6 and 8 were prepared by asymmetric dihydroxylation (AD) methodology and polymerization was carried out under Sonagashira coupling conditions. Polymer 1 was obtained in good yield with a molecular weight Mn = 5,100 (PDI = 2.3). Modeling suggests that polymer 1 could form a stable helical mainchain conformation in solution or the solid state. The chiroptical data of the polymer and a low‐molecular weight model compound (9) are compared. Chirality 14:258–263, 2002. © 2002 Wiley‐Liss, Inc.
Ab initio (CASPT2) excited state calculations, including circular dichroism, of helically twisted cyanine dyes
Authors: Schreiber Marko , Vahrenhorst Rainer , Buss Volker , Fülscher Markus P. 
Published: August 2002

AbstractAb initio calculations at the CASSCF/CASPT2 level were performed on helically twisted mono‐, tri‐, and pentamethine cyanine dyes in the all‐Z‐configurations. Excitation energies and oscillator and rotatory strengths were calculated for the five lowest energy singlet states. Both the long wavelength methine band and the cis‐band could be identified unambiguously from their configurational parentage. The calculated state energies are within 0.09 eV of the experimental value for the methine band and within 0.16 eV for the cis‐band. The calculated rotatory strengths of the methine band shows sign inversion as the length of the chromophore increases: negative for the short monomethine, strongly positive for the pentamethine. The trimethine presents a borderline case: the measured rotatory strength is almost nil, the calculated one depends on the geometry. There is good agreement between rotatory strengths calculated in the velocity and in the length formalism. Chirality 13:571–576, 2001. © 2001 Wiley‐Liss, Inc.
Mechanism of chiral recognition in the enantioseparation of 2‐aryloxypropionic acids on new brush‐type chiral stationary phases
Authors: Vinkovic Vladimir , Kontrec Darko , Sunjic Vitomir , Navarini Luciano , Zanetti Flavio , Azzolina Ornella 
Published: August 2002

AbstractNew brush‐type chiral stationary phases (CSP I–IV) comprising N‐3,5,6‐trichloro‐2,4‐dicyanophenyl‐L‐α‐amino acids (1–4) were prepared by binding of chiral selectors 1–4 to γ‐aminopropyl silica gel. To check the role of excess free aminopropyl groups, CSP V was prepared by binding N‐3,5,6‐trichloro‐2,4‐dicyanophenyl‐L‐alanyl‐(3‐triethoxysilyl)propylamide to unmodified silica gel. The best separation of racemic 2‐aryloxypropionic acids (TR‐1‐13) was obtained with CSP I; the ‐(−)‐S enantiomer were regularly eluted first, as determined by a CD detector. The mechanism of chiral recognition implies a synergistic interaction of carboxylic acid analyte with the chiral selector and achiral free γ‐aminopropyl units on silica. In fact, CSP V, which is lacking an achiral aminopropyl spacer, shows a lower separation ability for 2‐aryloxypropionic acids, but a similar enantioselective discrimination of esters TR‐19‐20, in comparison with CSP I. CSP I–IV retain unaltered separation ability after a few months of continuous work using a large number of various mobile phases. Chirality 13:581–587, 2001. © 2001 Wiley‐Liss, Inc.
Intelligent agents for competitive intelligence: Survey of applications
Authors: Desouza Kevin C. 
Published: August 2002

AbstractIn this article the author discusses a rather recent paradigm to artificial‐intelligence‐based computing, namely intelligent agents for generating competitive intelligence. The explosion in Internet use and private network development can be viewed as both a blessing and a curse. Companies that can effectively manage available information without suffering from “information overload” are leaders in their industry as they generate competitive intelligence. Those who drown in the information are part of history or will be soon. The article concludes by highlighting a series of business cases exemplifying the benefits of intelligent agents. © 2001 John Wiley & Sons, Inc.