bluuebunny/crossref_metadata_2025_split huggingface dataset:
Обґрунтування підходу до удосконалення інформаційної інфраструктури Міністерства оборони України для функціонування в умовах збройної агресії
Authors: Кірпічніков Ю. , Рибидайло А. , Литовченко Г. , Бутенко М. 
Published: November 2023

В умовах воєнно-політичної кризи та збройної агресії проти України, її державним інститутам, зокрема Міністерству оборони (МО) України, належить виробити і застосувати нові сучасні підходи до розвитку власного інформаційного простору, забезпечення його стійкості та безпеки. Особливостями розвитку інформаційної інфраструктури на сучасному етапі є високий рівень уніфікації апаратних, зокрема обчислювальних засобів (інфраструктура як сервіс), системного програмного забезпечення (базових сервісів), впровадження різного за призначенням прикладного спеціального програмного забезпечення (функціональних сервісів). Забезпечення належної якості сервісів є динамічною задачею, складність якої пропорційна завданням та вимогам до інформаційної інфраструктури.
Мета статті – обґрунтування рекомендацій стосовно шляхів удосконалення інформаційної інфраструктури Міністерства оборони України з урахуванням можливостей новітніх ІТ-технологій для забезпечення її функціонування та надійного застосування в умовах збройної агресії.
Побудова інформаційної інфраструктури для оборонних потреб може бути реалізована за допомогою різних підходів. Кожному з підходів притаманні власні переваги і недоліки та їх використання доцільне за певних умов і цілей створення інформаційної інфраструктури. Реалізація об’єднаного підходу при створенні інформаційної інфраструктури для її стійкого функціонування в умовах збройної агресії потребує проведення аналізу потреб та можливостей у рамках конкретного контексту конфлікту (або збройної агресії). Удосконалення інформаційної інфраструктури на основі об’єднаного підходу є складним проєктом. Запропоновано порядок удосконалення інформаційної інфраструктури МО України.
Birth defect: Findings from Obstetrics & Gynae Department of a tertiary Hospital
Authors: Alam Irin Parveen , Jahan Eva Nusrat 
Published: November 2023

Objectives: To determine the frequency and types of birth defect among newborn in Sir Salimullah Medical College Hospital Study Design: Cross-sectional study.
Methods: The study was conducted in Sir Salimullah Medical College Hospital from January- December 2018. Birth defect identified previously during pregnancy on USG or defect detected at birth at Obstetrics department were included in the study. The study was conducted at Obstetrics department of SSMC MH. All births with gross congenital malformations were noted. All malformations were classified as per ICD 10 classification. The mother of the newborn with congenital malformations was interviewed consecutively using predesigned, pretested questionnaire. The variables included parents age, antenatal registration, antenatal history of drug intake, consanguinity and previous history of malformations. Statistical analysis was done using chi square test.
Results: Out of 8912 live births, congenital malformations were observed in 50 cases. The frequency of congenital malformation was 0.56%. There were 25 males and 23 females and two newborns had ambiguous genitalia. The highest congenital abnormality reported in this study was in the age group between 20-29 years, which was 31(62%), The central nervous system was the most common system involved. Among 50 neonates, 8 neonate had multiple congenital anomalies and 42 babies had isolated malformations.
Bangladesh J Obstet Gynaecol, 2022; Vol. 37(2): 127-131
Scar Ectopic: Diagnostic and Management Challenge
Authors: Saha Joysree , Podder Priyanka 
Published: November 2023

Scar ectopic pregnancy is the rarest form of ectopic pregnancy and has been increasingly diagnosed all over the world. Usually when a blastocyst implants on the fibrous tissue of the previous Caesarean scar is called scar ectopic. This type of abnormal implantation of embryo can occur following hysterotomy, dilatation and curettage ,abnormal placentation surgery on uterus like myomectomy ,hysteroscopy and manual removal of placenta. The incidence is increased due to increase in number of Caesarean deliveries. Trans vaginal Sonography helps in early diagnosis. Early diagnosis leads to prompt management and improves the outcome by allowing preservation of future fertility. Excision of trophoblastic tissues using laparotomy or laparoscopy, systemically administered methotrexate, and more recently uterine artery embolization are the treatment options for scar ectopic. When TVS is inconclusive, MRI can be recommended.
We are reporting here a case of first trimester caesarean scar pregnancy with viable fetus in the process of rupture, where uterine repair could be done to preserve the future fertility.
Bangladesh J Obstet Gynaecol, 2022; Vol. 37(2): 154-156
Penggunaan Media Sosial Untuk Pemasaran Produk Kerajinan Tangan di Kelurahan Bentiring Kota Bengkulu
Authors: Pasaribu Esti , Ekaputri Retno Agustina , Yusnida  , Yefriza  , Putri Novi Tri , Septriani  
Published: November 2023

Women have a big role in the economy, especially during the pandemic covid-19. In this situation, many people can not stand in normal way for selling and buying. The others lost their jobs because the economy were not running well. For this reason, it is necessary to carry out Community Service (PPM) by taking place in the Bentiring Village, Bengkulu City. Activities was carried out in November 2020 not only by providing training on making handicraft accessories but also facilitating them to sell it online using social media. The participants of this activity is representatives of housewives. Online marketing of handicraft accessories will help the community in increasing family income during the pandemic.
Analisis Kekritisan dan Rasio Konversi Reaktor Cepat Berpendingin Gas dengan Variasi Fraksi Bahan Bakar UN-PuN Menggunakan Skema Burn-up Modified CANDLE Arah Radial
Authors: Irka Feriska Handayani , Su'ud Zaki , Irwanto Dwi , Khotimah Siti Nurul , Sekimoto Hiroshi 
Published: November 2023

Analysis of the criticality and conversion ratio of a gas-cooled fast reactor (GFR) with various UN-PuN fuel fractions using modified CANDLE scheme burn-up in radial direction has been conducted. The fuel fraction varies from 40% - 60% with 5% intervals, the cladding fraction is 10% and the coolant fraction varies from 30% -50%. Data calculations were performed using SRAC 2006 programming with JENDL 4.0 library data. The reactor is divided into 10 regions with equal volume in the radial direction. Each region is filled with natural uranium fuel without enrichment with different burn-up levels. Regions are arranged in such a way that the reactor can reach critical conditions throughout the burn-up period. The results showed that variations in the 40% fuel fraction had not been able to reach critical conditions at the beginning of life, while 45%-60% fuel fraction variations had reached reactor criticality. The conversion ratio for all fuel fractions is greater than 1, which indicates that a breeding process appears in the GFR reactor core. The conversion ratio for all variations in fuel fractions has almost the same pattern for all regions. The first region has the largest conversion ratio value because it has natural uranium as fuel input which has the highest density compared to other regions.
The Next Stage of Federalization of the European Union
Authors: Sаvkova Mariela 
Published: November 2023

Today, from the distance of time, it is clear that during the last 15 years, the European Union and Euro-Atlantic unity have been under attack from the revived nationalist movements in the member-states. It is difficult to name their direct “sponsor”, but the external and internal threats to the European Union are certainly growing, most visibly after the barbarian attack of Russia over Ukraine a year ago.
The manuscript analyses some aspects of European federalism in comparison with the American and Canadian models and what is the way forward for the EU. After the United Kingdom’s departure became obvious that the economic convergence of a member-state is insufficient for sustainable European integration.
The process of Europeanisation of Europe is been analyzed with the view of the EU enlargement and the achievements of the first phase of federalization of the European Union. The main questions for the author are what the political future of the EU is and how to strengthen its unity to deal more efficiently with today’s challenges.
Patterns of de novo metastasis and survival outcomes by age in breast cancer patients: a SEER population-based study
Authors: Xiao Qian , Zhang Weixiao , Jing Jingfeng , Zhong Tingting , Li Daxue , Zhou Jing , Liu Pan , Duan Zhongxu , Gao Han , Shen Liyuan 
Published: November 2023

BackgroundThe role of age in metastatic disease, including breast cancer, remains obscure. This study was conducted to determine the role of age in patients with de novo metastatic breast cancer.MethodsBreast cancer patients diagnosed with distant metastases between 2010 and 2019 were retrieved from the Surveillance, Epidemiology, and End Results database. Comparisons were performed between young (aged ≤ 40 years), middle-aged (41–60 years), older (61–80 years), and the oldest old (&gt; 80 years) patients. Adjusted hazard ratios (aHRs) and 95% confidence intervals (CIs) were estimated using multivariate Cox proportional hazard models. Survival analysis was performed by the Kaplan–Meier method.ResultsThis study included 24155 (4.4% of all patients) de novo metastatic breast cancer patients. The number of young, middle-aged, older, and the oldest old patients were 195 (8.3%), 9397 (38.9%), 10224 (42.3%), and 2539 (10.5%), respectively. The 5-year OS rate was highest in the young (42.1%), followed by middle-aged (34.8%), older (28.3%), and the oldest old patients (11.8%). Multivariable Cox regression analysis showed that middle-aged (aHR, 1.18; 95% CI, 1.10–1.27), older (aHR, 1.42; 95% CI, 1.32–1.52), and the oldest old patients (aHR, 2.15; 95% CI, 1.98–2.33) had worse OS than young patients. Consistently, middle-aged (aHR, 1.16; 95% CI, 1.08–1.25), older (aHR, 1.32; 95% CI, 1.23–1.43), and the oldest old patients (aHR, 1.86; 95% CI, 1.71–2.03) had worse BCSS than young patients.ConclusionThis study provided clear evidence that de novo metastatic breast cancer had an age-specific pattern. Age was an independent risk factor for mortality in patients with de novo metastatic breast cancer.
Genetic variations underlying Gilbert syndrome and HBV infection outcomes: a cross-sectional study
Authors: Yao Bilian , Xu Qi , Zhang Xinxin , Han Yue 
Published: November 2023

Background: Constant cellular damage causes a poor prognosis of hepatitis B virus (HBV) infection. Accumulating evidence indicates the cytoprotective properties of bilirubin. Here, we investigated the association of UDP glucuronosyltransferase family 1 member A1 (UGT1A1), the genetic cause of Gilbert syndrome (GS), a common condition of mild unconjugated bilirubinemia, with HBV infection outcomes.Methods: Patients (n = 2,792) with unconjugated hyperbilirubinemia were screened for HBV infection and host UGT1A1 variations in Ruijin Hospital from January 2015 to May 2023, and those with confirmed HBV exposure were included. The promoter/exons/adjacent intronic regions of UGT1A1 were sequenced. HBV infection outcomes were compared between hosts with wild-type and variant-type UGT1A1. The effect magnitudes of UGT1A1 variations were evaluated using three classification approaches.Results: In total, 175 patients with confirmed HBV exposure were recruited for final analysis. Age, gender, level of HBV serological markers, and antiviral treatment were comparable between UGT1A1 wild-type and disease-causing variation groups. Five known disease-causing mutations (UGT1A1*28, UGT1A1*6, UGT1A1*27, UGT1A1*63, and UGT1A1*7) were detected. The incidence of cirrhosis or hepatocellular carcinoma (LC/HCC) was significantly lower in UGT1A1 variant hosts than in UGT1A1 wild-type hosts (13.14% vs. 78.95%, p &lt; 0.0001). The rarer the UGT1A1 variation a patient possessed, the higher the age at which LC/HCC was diagnosed (R = 0.34, p &lt; 0.05). In contrast, patients without cirrhosis achieving HBsAg clearance were identified only in the UGT1A1 variant group (12.32% vs. 0%).Conclusion: The findings of this study provide insights into the association between preexisting genetically mild bilirubin elevation and viral infection outcome. We showed that the accumulation of UGT1A1 variants or the rarity of the variation is associated with a better prognosis, and the effect magnitude correlates with UGT1A1 deficiency. This study demonstrates the therapeutic potential of host UGT1A1 variations underlying GS against HBV infection outcomes.
Feasibility of apalutamide combined with androgen deprivation therapy and short-course low-dose prednisone in treating metastatic hormone-sensitive prostate cancer: a pilot randomized controlled trial
Authors: Yang Dingyuan , Chen Wenqiang , Lai Fei , Qiu Mingxing , Li Jun 
Published: November 2023

IntroductionThe role of prednisone in the prevention of androgen receptor antagonist-related rash and treatment for metastatic hormone-sensitive prostate cancer (mHSPC) is unclear. This pilot trial (ChiCTR2200060388) aimed to investigate the feasibility of apalutamide combined with androgen deprivation therapy (ADT) and short-course low-dose prednisone in the treatment of mHSPC.MethodsAll patients received apalutamide and ADT and were randomly divided into two groups based on the administration of oral prednisone or not (control group). The primary endpoint was the incidence of rash. The secondary endpoint included the proportions of patients with a decline in PSA ≥50% from baseline, PSA ≥90% from baseline, and decreased to PSA ≤0.2 ng/mL.ResultsBetween June 2021 and March 2022, a total of 83 patients were enrolled (41 in the prednisone group and 42 in the control group). During the 6-month follow-up, the incidence of rash was significantly lower in the prednisone group compared with the control group (17.1% vs. 38.1%, P=0.049). There were no significant differences in the incidence of other adverse events, the number of patients who required dose adjustment (reduction, interruption, or discontinuation) of apalutamide due to rash, the number of patients with prostate-specific antigen (PSA) decreased by ≥50%, the number of patients with PSA decrease ≥90%, and the number of patients with PSA ≤0.2 ng/mL between the two groups. All patients with diabetes had stable glycemic control with no glucose-related adverse events.DiscussionIn patients with mHSPC, the addition of short-course low-dose prednisolone to apalutamide plus ADT can reduce the incidence of rash without risk of other adverse events.
Healthy helpers: using culinary lessons to improve children’s culinary literacy and self-efficacy to cook
Authors: Policastro Peggy , Brown Alison H. , Comollo Erin 
Published: November 2023

BackgroundChildren do not eat the recommended amounts of vegetables, and school-based nutrition education has not been found to impact this behavior. Cooking education is associated with improved children’s culinary literacy (CL) and eating behaviors. This study investigated the impact of a culinary literacy (CL) curriculum on children’s acceptance of vegetable-added (mushrooms) recipes, CL, self-efficacy to cook (SE), and willingness to try vegetables (WV).MethodsA convenience sample of 39 fourth and fifth graders were exposed to a six-lesson virtual CL curriculum that taught basic cooking skills and how to prepare six recipes, including three traditional recipes and the same recipes with added vegetables.ResultsChildren who participated in the CL curriculum accepted vegetables added to pizza pockets, but vegetables added to macaroni and cheese and fajitas negatively affected the acceptance of recipes. Children improved their CL and SE but did not show a significant change in their WV.ConclusionFindings suggest that CL programs focusing on vegetables may drive factors associated with dietary behavior change, SE, and acceptance of vegetables. Future studies should consider CL as a potential method to improve vegetable intake in children in tandem with nutrition education or as a sole intervention. The study was limited by its small sample size, the virtual setting, and the use of mushrooms as the primary vegetable source. Future studies should be conducted with a larger sample size, in a traditional classroom setting, use a variety of vegetables, and collect qualitative data on the sensory characteristics affecting children’s WV.
Early life programming by diet can play a role in risk reduction of otitis in dogs
Authors: Hemida Manal B. M. , Vuori Kristiina A. , Borgström Nona C. , Moore Robin , Rosendahl Sarah , Anturaniemi Johanna , Estrela-Lima Alessandra , Hielm-Björkman Anna 
Published: November 2023

IntroductionOtitis in dogs is often chronic while local treatment primarily consists of flushing, antibiotics, and/or antifungals. We were interested in finding early life variables that associate with otitis later in life, preferably some that could be modified.MethodsA cross-sectional hypothesis-driven study with longitudinal data was performed to search for associations between pre- and postnatal exposures, and the incidence of owner-reported otitis in dogs at over 1 year of age. The multivariate logistic regression analysis study included data from 3,064 dogs and explored 26 different early life variables at four early life stages: prenatal, neonatal, postnatal, and puppyhood. We compared two feeding patterns, a non-processed meat-based diet (NPMD, raw) and an ultra-processed carbohydrate-based diet (UPCD, dry).ResultsWe report that eating a NPMD diet significantly decreased the risk of otitis later in life, while eating a UPCD diet significantly increased the risk. This was seen in different life stages of mother or puppy: The maternal diet during pregnancy (p=0.011) and the puppies’ diet from 2 to 6 months of age (p=0.019) were both significantly associated with otitis incidence later in life, whereas the puppies’ first solid diet, was associated in the same way, but did not reach significance (p=0.072). Also, analyzing food ratios showed that when puppies were consuming &gt;25% of their food as NPMD it significantly decreased their incidence of otitis later in life, while a ratio of &gt;75% UPCD in their diet significantly increased their risk of otitis. Also, if the dog was born in the current family, was exposed to sunlight for more than 1 hour daily, and was raised on a dirt floor during puppyhood, there was a lower risk of otitis development later in life.DiscussionThe findings only suggest causality, and further studies are required. However, we propose that veterinarians, breeders, and owners can impact otitis risk by modifying factors such as diet and environment.
PENGARUH PENERAPAN SISTEM INFORMASI E-SAMSAT TERHADAP TINGKAT KEPATUHAN WAJIB PAJAK KENDARAAN BERMOTOR
Authors: Alghaviqi Muhammad Wafqi Aufa , Ishak Jouzar Farouq 
Published: November 2023

Penelitian ini dilakukan untuk mengetahui pengaruh penerapan sistem informasi E-Samsat terhadap kepatuhan wajib pajak kendaraan bermotor di kantor SAMSAT Kabupaten Garut. Metode penelitian yang digunakan adalah deskriptif kuantitatif. Jumlah sampel yang digunakan dalam penelitian ini adalah 100 responden dengan beberapa kriteria. Data primer diperoleh melalui kuesioner. Dari hasil uji koefisien determinasi, penerapan sistem informasi E-Samsat memberikan pengaruh terhadap tingkat kepatuhan wajib pajak kendaraan bermotor sebesar 29,5%. Adapun dari hasil pengujian hipotesis terlihat nilai thitung sebesar 6,407 dan nilai ttabel sebesar 1,984. Hasil tersebut menunjukkan bahwa nilai thitung lebih besar dari nilai ttabel sehingga dapat disimpulkan bahwa H0 ditolak dan H1 diterima. Dengan demikian dapat disimpulkan bahwa terdapat pengaruh positif antara penerapan sistem informasi E-Samsat terhadap kepatuhan wajib pajak kendaraan bermotor di Kabupaten Garut.
Kata kunci: E-Samsat, Pajak Kendaraan Bermotor, Kepatuhan Wajib Pajak
Currency Fluctuations and Islamic Stock Indices in Emerging Markets
Authors: Mubarok Faizul 
Published: November 2023

This research aims to explain why Islamic stock indexes tend to track the currency exchange rates of emerging countries. Granger causality is used in this analysis, and it is applied to daily data beginning with the day the index was first formed for each country. The Islamic stock indices of Malaysia, Indonesia, and India were employed as a research sample in this study. According to the findings of the research, there is only a correlation in one direction between the Islamic stock index and the currency exchange rate. Both the Islamic stock indexes in Malaysia and India have an effect on the currency exchange rate in that nation, whereas the currency exchange rate in India affects the Islamic stock index. This finding is helpful as a source of data in determining policies for the development of the Islamic financial system because it was discovered that.
Keywords: Islamic Stock; Granger Causality; Exchange Rates; Developing Country
Analysis of the Influence of Online Promotion, Product Packaging and Price on Purchasing Decisions with Price as a Moderating Variable
Authors: Firdaus* Edi , Hurriyati Ratih , Dirgantari Dwi Puspo , Murugesu Karina Devi 
Published: November 2023

This study aims to find out how online promotions, product packaging and prices affect purchasing decisions for culinary products "Cau Nugget" and to determine the effect of price moderation on online promotions in determining purchasing decisions. This study used a quantitative method involving consumer Instagram followers 'Cau Nugget' as a population and a sample of 121 respondents. The results of the study found that, of the three existing factors, online promotions did not have a significant influence on purchasing decisions. Meanwhile, product packaging and price have a significant effect on purchasing decisions. This study proves that price negatively moderates online promotions on purchasing decisions, as well as being the indicator that has the highest impact on purchasing decisions.
Keywords: Online Promotion; Product Packaging; Price; Buying Decision; Home Industry
Digital Marketing Utilization Determinants: Study on MSEs in Salatiga City
Authors: Fevriera Sotya , Saraswati Birgitta Dian , Adhitya Dhian , Siwi Virgiana Nugransih , Wahyudi* Yustinus 
Published: November 2023

This research aims to identify the factors influencing the use of digital marketing by Micro, Small, and Medium Enterprises (MSMEs) and to examine the factors affecting the preference for digital marketing usage by MSMEs in the city of Salatiga. The research sample consists of 135 business units representing MSMEs in Salatiga. Data analysis techniques involve descriptive statistical analysis, qualitative analysis, binomial and multinomial logistic regression. The research findings provide evidence of the implementation of the UTAUT theory, particularly concerning performance expectations and facilitating conditions, significantly influencing the probability of digital marketing usage and the marketing of business products. Surprisingly, acceptance as part of performance expectations has a negative impact on digital marketing usage, especially on social media platforms. Furthermore, digital marketing proves to be of paramount importance for MSMEs looking to expand their businesses.
Keywords: MSMEs; Digital Marketing; Covid-19; UTAUT Theory; Logistic Regression