bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Report: Gastrointestinal neuroendocrine carcinoma with SMARCA4 deficiency: a clinicopathological report of two rare cases
Authors: Zhou Ping , Fu Yiyun , Wang Weiya 
Published: November 2023

BackgroundGastrointestinal neuroendocrine carcinoma (GI NEC) is a rare but highly malignant neoplasm with an aggressive clinical course. SMARCA4 is one of the subunits of the SWI/SNF chromatin remodeling complex. SMARCA4 deficiency can occur rarely in subsets of NECs. Reports of the clinicopathological features of GI NECs with SMARCA4 deficiency are limited.MethodsIn this study, we retrospectively reported two rare cases of GI NEC with SMARCA4 deficiency and described the clinicopathological, radiographic and histopathological features.ResultsCase 1 was a 43-year-old male with a stage cT3NxM1, IV tumor. Case 2 was a 64-year-old female with a stage cT4aN1M0, IIIA tumor. Both tumors presented as ulcerated masses with infiltration. Pathological examination indicated a solid architecture with poorly differentiated morphology, and complete loss of SMARCA4 (BRG1) was found. Immunohistochemical staining showed positivity for Syn, CgA and CD56. The Ki-67 index was 90% and 70%, respectively. None of the cases had mismatch repair (MMR) deficiency. Case 1 received treatment with chemotherapy and anti-PD-1 immunotherapy. He did not respond to treatment, and died 9 months later. Case 2 received neoadjuvant chemotherapy before surgical treatment, and the tumor showed TRG3 in response to neoadjuvant chemotherapy, chemotherapy and anti-PD-1 immunotherapy were continued after surgical resection. There was no evidence of disease for 10 months.ConclusionsGI NEC with SMARCA4 deficiency is a rare entity of gastric NEC. SMARCA4 may be a promising targetable and prognostic biomarker. BRG1 immunohistochemical staining could be performed for GI NECs. Further studies with a larger cohort will be needed.
Pulse shaping, high average power narrow linewidth Er, Yb co-doped fiber amplifier
Authors: Wang Yunpeng , Li Yang , Zhang Dongming , Xiong Chen , Li Pingxue 
Published: November 2023

We demonstrate a high repetition rate, high average power narrow-linewidth fiber amplifier at 1.55 μm eye-safe waveband by using a very-large-mode-area active fiber doping Er and Yb, having a 60-μm-diameter core and a 600-μm-diameter inner cladding. A maximum average power reaches 16 W at a 10 kHz repetition rate for 600 ns pulses in the stimulated Brillouin scattering (SBS) free operation, which calculates to a 1.6 mJ pulse energy and 2.7 kW peak power. In addition, the peak power rises to 4.9 kW with 148 ns pulses at the onset of SBS. The signal peak is located at 1,551.15 nm with a 36 dB signal-to-noise ratio (SNR). In order to eliminate the pulse steepening, the pulse shaping technology using a triangular-like wave with a slower rising edge is applied on the input pulses. The half-width of the frequency-intensity spectrum from high-average-power fiber amplifier is about 1.02 MHz, approaching the Fourier transform limit.
The psychology of romantic relationships: motivations and mate preferences
Authors: Tartakovsky Eugene 
Published: November 2023

IntroductionThis study investigates motivations to engage in romantic relationships. We examine the structure of romantic motivations and their connections with personal values and mate preferences.MethodThe study was conducted in Israel among young men and women looking for a romantic partner (n = 1,121, 40% male, age 18–30).ResultsData analysis demonstrated that basic romantic motivations form a circumplex that may be partitioned into four higher-order romantic motivations: love and care, family and children, status and resources, and sex and adventure. The romantic motivations formed a meaningful pattern of connections with higher-order values, thus confirming that context-specific motivations are derived from general motivational goals expressed in values. Personal value preferences and romantic motivations predicted the sought-after partner characteristics over and above sociodemographic variables. Values were indirectly (through romantic motivations) and directly connected to mate preferences.DiscussionThe study advances our understanding of romantic relationships among young people and opens new directions for research and counseling.
Influence of different caregiving styles on fundamental movement skills among children
Authors: Hu Jiahui , Zhang Shudan , Ye Weibing , Zhu Yuanye , Zhou Huiling , Lu Lihua , Chen Qian , Korivi Mallikarjuna 
Published: November 2023

PurposeThis study investigated the influence of parenting and grandparenting caregiving styles on fundamental motor skills (FMS) of preschool children.MethodA total of 1,326 preschool children (698 boys, 628 girls) aged 4–6 years were recruited from the kindergartens of Jinhua City, China. Locomotor skills (LM), ball skills (BS), and total fundamental movement skills (TS) of children were assessed by the Test of Gross Motor Development-3rd edition (TGMD-3).ResultsThere were 978 children in parenting and 348 children in grandparenting caregiving styles. The LM, BS and TS scores of children were considerably (p &lt; 0.001) increased with age (irrespective of sex or caregiving style). For the sex comparisons, BS scores of boys were significantly higher than girls (p &lt; 0.001), while LM and TS scores were not different between boys and girls. For the caregiving style comparison, parenting is superior to grandparenting in developing of children's FMS. Parenting boys of 4-, 5-, and 6-years old showed better BS compared to age-matched parenting girls, whereas boys of 5-years old in grandparenting only showed better BS compared to same-age grandparenting girls (p &lt; 0.05). Furthermore, parenting boys of 6-years reported higher LM (p &lt; 0.01), BS (p &lt; 0.001), and TS (p &lt; 0.001) scores compared to grandparenting boys, but girls' FMS at all ages were not significantly different between the caregiving styles.ConclusionParenting caregiving style is positively associated with proper development of FMS among children. Girl children with poor FMS in grandparenting may need a special care or intervention programs to promote their FMS.
Insights from China: understanding the impact of community resilience and government trust in psychological resilience and anxiety during COVID-19
Authors: Hu Yue , Huang Yuxin , Zhang Hua , Fang Min , Chen Guobang 
Published: November 2023

BackgroundCOVID-19 has the potential to greatly impact an individual mental well-being. However, an individual’s psychological resilience, combined with support from their community and government disaster relief efforts can aid individuals in confronting crises with a positive mindset. The purpose of this study is to investigate how individuals, across three dimensions of individual resilience perception, community resilience perception, and government trust perception, mitigate individual anxiety during COVID-19.MethodsThis study employed an online survey method that was not restricted by geographical location. Data collection took place from January 2022 to June 2022, and the valid questionnaires covered all 31 provinces, autonomous regions, and municipalities in China. The assessment of community resilience was conducted employing the Conjoint Community Resilience Assessment Measure-10 (CCRAM-10). Structural Equation Modeling (SEM) was also used to examine the relationship between community resilience, government trust, individual psychological resilience, and anxiety.ResultsThe SEM results reveal that individual psychological resilience is significantly negatively correlated with anxiety (b = −0.099, p &lt; 0.001), while there is a significant positive correlation between community resilience perception (b = 0.403, p &lt; 0.001) and government trust (b = 0.364, p &lt; 0.001) with individual psychological resilience. Furthermore, government trust perception enhances psychological resilience, consequently reducing anxiety (b = −0.036, p &lt; 0.001). The results also revealed that women and increasing age had a mitigating effect on individual anxiety during COVID-19.ConclusionIndividual’s mental state is influenced on multiple dimensions during COVID-19. Not only can individual psychological resilience better cope with anxiety, but support at the community and government dimensions has a significant impact on individual psychology. These resources can enhance the resilience of both individuals and communities, helping them better cope with stress and difficulties.
Hazardous, harmful, and dependent alcohol use in healthcare professionals: a systematic review and meta-analysis
Authors: Halsall Lauren , Irizar Patricia , Burton Sam , Waring Sara , Giles Susan , Goodwin Laura , Jones Andrew 
Published: November 2023

BackgroundHealthcare professionals work in high-pressured and demanding environments, which has been linked to the use of alcohol as a coping strategy. This international review aimed (i) to determine the pooled prevalence of hazardous, harmful, dependent, and frequent binge drinking in healthcare professionals, and (ii) to explore factors associated with variation in these outcomes.MethodsScopus, MEDLINE, and PsycINFO were searched from 2003 to 17th November 2022, for studies reporting a prevalence estimate for any outcome among healthcare professionals. Random-effects meta-analyses determined pooled prevalence estimates. Sub-group analyses were conducted, stratifying the meta-analyses by pandemic period vs pre-pandemic period. Meta-regressions explored factors that were associated with variation in the outcomes. PROSPERO (CRD42020173119).ResultsAfter screening 9,108 records, 64 studies were identified as eligible. The pooled prevalence was 19.98% [95% Confidence Intervals [CI]: 16.05–24.23%] for hazardous alcohol use (K = 52), 3.17% [95% CI: 0.95–6.58%] for harmful drinking (K = 8), 14.59% [95% CI: 7.16–25.05%] for dependent drinking (K = 7), and 17.71% [95% CI: 8.34–29.63%] for frequent binge drinking (K = 11). The prevalence of hazardous drinking was greater during the pandemic (28.19%) compared with pre-pandemic estimates (17.95%), though this was not statistically significant (p = 0.049). Studies including all hospital staff (32.04%) showed higher prevalence estimates for hazardous drinking compared with studies of doctors (16.78%) and nurses (27.02%).ConclusionApproximately one fifth of healthcare professionals drink to hazardous levels, with higher prevalence estimates observed during the COVID-19 pandemic. It may be that healthcare professionals used alcohol to cope with the additional trauma and stressors. Further research is needed to investigate whether this is sustained in the post-pandemic period.
Assessment of indoor air quality in health clubs: insights into (ultra)fine and coarse particles and gaseous pollutants
Authors: Peixoto Cátia , Pereira Maria do Carmo , Morais Simone , Slezakova Klara 
Published: November 2023

IntroductionExercising on regular basis provides countless health benefits. To ensure the health, well-being and performance of athletes, optimal indoor air quality, regular maintenance and ventilation in sport facilities are essential.MethodsThis study assessed the levels of particulate, down to the ultrafine range (PM10, PM2.5, and particle number concentration in size range of 20–1,000 nm, i.e., – PNC20-1000 nm), gaseous pollutants (total volatile organic compounds – TVOCs, CO2, and O3) and comfort parameters (temperature – T, relative humidity – RH) in different functional spaces of health clubs (n = 8), under specific occupancy and ventilation restrictions.Results and DiscussionIn all HCs human occupancy resulted in elevated particles (up to 2–3 times than those previously reported), considering mass concentrations (PM10: 1.9–988.5 μg/m3 PM2.5: 1.6–479.3 μg/m3) and number (PNC 1.23 × 103 – 9.14 × 104 #/cm3). Coarse and fine PM indicated a common origin (rs = 0.888–0.909), while PNC showed low–moderate associations with particle mass (rs = 0.264–0.629). In addition, up to twice-higher PM and PNC were detected in cardiofitness &amp; bodybuilding (C&amp;B) areas as these spaces were the most frequented, reinforcing the impacts of occupational activities. In all HCs, TVOCs (0.01–39.67 mg/m3) highly exceeded the existent protection thresholds (1.6–8.9 times) due to the frequent use of cleaning products and disinfectants (2–28 times higher than in previous works). On contrary to PM and PNC, TVOCs were higher (1.1–4.2 times) in studios than in C&amp;B areas, due to the limited ventilations combined with the smaller room areas/volumes. The occupancy restrictions also led to reduced CO2 (122–6,914 mg/m3) than previously observed, with the lowest values in HCs with natural airing. Finally, the specific recommendations for RH and T in sport facilities were largely unmet thus emphasizing the need of proper ventilation procedures in these spaces.
The function of mating plugs in the spider Neriene emphana: mating strategy or sperm protection?
Authors: Tian Shuang , Jiang He , Zhan Yongjia , Wu Qingqing , Kuntner Matjaž , Tu Lihong 
Published: November 2023

IntroductionIt is generally thought that mating plugs, where present, impede or reduce the possibilities of female subsequent mating. Behavioral studies on numerous spiders, where mating plugs are common, have generally supported this function. However, mating plugs in spiders could plausibly serve other functions as well. Namely, the structure of entelegyne spermathecae—the morphology of most spiders—could require a mechanism that would prevent sperm from leakage, desiccation, and backflow. Although the form and function of mating plugs in several spider species imply their potential adaptation for sperm protection, this function has never been empirically tested.MethodsHere, we test whether mating plugs in the sheet-web spider Neriene emphana serve as a sperm protective device by investigating its genital morphology, its copulation process, and the precise formation of its amorphous mating plugs. ResultsThis species constructs secretion plugs through male-female cooperation. Additionally, we found sperm plugs to be formed as a side product of sperm transfer, as well as an intermediate type of secretion plugs. These plug materials are transferred in different mating stages as documented by variations in the rhythm of male palpal application during copulation. We showed that complete copulations always resulted in formation of secretion plugs at spermathecal entrances via laborious deposition of male materials. DiscussionWhile our findings do not reject that secretion plugs in N. emphana prevent females from subsequent mating, we suggest that they must have evolved to provide sperm protection.
The impact of COVID-19 pandemic on pet behavior and human-animal interaction: a longitudinal survey-based study in the United States
Authors: Weng Hsin-Yi , Ogata Niwako 
Published: November 2023

IntroductionAlthough multiple studies have explored behavioral changes in pets during the strict lockdown of the COVID-19 pandemic between May and July 2020, this longitudinal study uniquely investigated the phases beyond strict lockdown. The primary objective of this research was to evaluate the pandemic’s impact on pet behavior.MethodsTo achieve this goal, we conducted an online survey, completed by pet owners residing in the United States between June 2020 (including retrospective data for February and April 2020) and December 2021. The study encompassed four distinct pandemic phases: Pre-pandemic (data collected retrospectively), Strict lockdown, Prolonged lockdown, and Re-opening.Results and discussionThe data collected from surveys completed by 3,278 pet owners across one to six time points revealed declining trends in all investigated behavior problems of both dogs and cats. Concurrently, human-animal interaction activities also showed variations across different COVID-19 phases. The association between human-animal interactions and the occurrence of behavior problems underscored the importance of not only exercise quantity but also adherence to consistent schedules, particularly for dogs, in mitigating behavior problems. Interestingly, among cats, sleeping outside the bedroom was associated with a reduced occurrence of aggression, anxiety, fear, and physiological behavior changes. However, sleep location displayed limited or no association with behavior problems in dogs. In summary, this study highlights the importance of tailoring interventions to the unique needs of each species through human-animal interactions to mitigate the occurrence of behavioral problems and enhance human-animal relationships.
Arthropods Associated with Invasive Frangula alnus (Rosales: Rhamnaceae): Implications for Invasive Plant and Insect Management
Authors: Greenleaf Jennifer , Holásková Ida , Rowen Elizabeth , Gutensohn Michael , Turcotte Richard , Park Yong-Lak 
Published: November 2023

The invasive shrub glossy buckthorn (Frangula alnus) has been progressively colonizing the Northeastern United States and Southeastern Canada for more than a century. To determine the dominant arthropod orders and species associated with F. alnus, field surveys were conducted for two years across 16 plots within the Allegheny National Forest, Pennsylvania, USA. Statistical analyses were employed to assess the impact of seasonal variation on insect order richness and diversity. The comprehensive arthropod collection yielded 2845 insects and arachnids, with hemipterans comprising the majority (39.8%), followed by dipterans (22.3%) and arachnids (15.5%). Notably, 16.2% of the hemipterans collected were in the immature stages, indicating F. alnus as a host for development. The two dominant insect species of F. alnus were Psylla carpinicola (Hemiptera: Psyllidae) and Drosophila suzukii (Diptera: Drosophilidae); D. suzukii utilized F. alnus fruits for reproduction. Species richness and diversity exhibited significant variations depending on the phenology of F. alnus. The profiles of volatile compounds emitted from the leaves and flowers of F. alnus were analyzed to identify factors that potentially contribute to the attraction of herbivores and pollinators. The results of our study will advance the development of novel F. alnus management strategies leveraging the insects associated with this invasive species.
The Problem of "Dual Diagnosis" in Psychiatry and an Attempt to Solve it
Authors: Скугаревский О.А. 
Published: November 2023

Обсуждена проблема коморбидности психических и поведенческих расстройств с точки зрения «двойного диагноза», когда проблемное употребление психоактивных веществ сосуществует с психическим расстройством. Сделан акцент на нейробиологических закономерностях, лежащих в основе взаимообусловленности тяжелых психических расстройств (шизофрения и биполярное аффективное расстройство) и проблемного употребления алкоголя. Представлены доказательства новизны использования парциального агониста дофаминовых рецепторов карипразина для влияния на ключевые биологические механизмы психотических расстройств (аффективные, когнитивные, продуктивные симптомы) и зависимости от психоактивных веществ.
The problem of comorbidity of mental and behavioral disorders is discussed from the point of view of a dual diagnosis, when problematic substance use coexists with a mental disorder. Emphasis is placed on the neurobiological patterns underlying the interdependence of severe mental disorders (schizophrenia and bipolar affective disorder) and problematic alcohol use. Evidence of the novelty of using the partial dopamine agonist cariprazine to influence the key biological mechanisms of psychotic disorders (affective, cognitive, productive symptoms) and substance dependence is presented.
PEMANFAATAN LIMBAH KULIT UDANG DALAM PEMBUATAN PRODUK PEMBERSIH TOILET GUNA MENANGGULANGI PENYEBARAN BAKTERI
Authors: Soraya Zalkha , Indrayani Syarthini , Chadijah Andi 
Published: November 2023

Pengabdian Kepada Masyarakat Pesisir Galesong Kabupaten Takalar menyangkut mengenai sumber penghasilan dari hasil tangkapan udang dilaut. Kegiatan pengabdian ini dilakukan dengan memanfaatkan hasil limbah dari kulit udang yang biasanya dibuang begitu saja tidak dimanfaatkan sehingga akan menumpuk mencemari lingkungan dan menyebabkan penyebaran bakteri.Tujuan dari pemanfaatan Limbah kulit udang tersebut adalah untuk menanggulangi penyebaran bakteri dan pencemaran lingkungan dan kesehatan, limbah kulit udang tersebut diolah dan akan dijadikan pembersih toilet yang bernilai ekonomis dan dapat menambah penghasilan dari masyarakat dipesisir galesong.
Metode pelaksaaan dengan menggunakan metode demonstrasi dari input sampai output dengan beberapa rancangan kegiatan yaitu Tahap persiapan meliputi perencanaan tempat, alat, bahan, dan waktu serta persiapan pengolahan kulit udang, tahap penyuluhan dan pelatihan, tahap mengevaluasi kegiatan hasil penyuluhan dan pelatihan yang dilakukan, tahap mengaplikasikan hasil produk di lingkungan masyarakat untuk mengurangi penyebaran bakteri dan tahap pendampingan kepada masyarakat dalam memasarkan suatu produk untuk meningkatkan ekonomi masyarakat di pesisir galesong.
Target dan Luaran yang ingin dicapai menghasilkan luaran artikel ilmiah yang akan dipublikasikan dalam jurnal nasional terakreditasi ber ISSN Sinta-5 Jurnal Pengabdian Kepada Masyarakat, modul pengabdian, HAKI, dan video pengabdian yang akan dipublikasikan di media sosial.

Kata Kunci: Ekonomi, Limbah udang, Mengurangi penyebaran bakteri
Amicus Curiae: Position and Role in Issuing Decisions by Judges as an Effort to Achieve Substantive Justice
Authors: Kholiq Abdul 
Published: November 2023

In practice of criminal justice system, a judge plays a fundamental role in making decision that will be imposed on the defendant. The Law on Judicial Power requires judges to widely disclose information and opinions from various groups and public participation. Amicus curiae concept is a mechanism that permits third parties who believe they are interested in a particular criminal case. However, the existence of amicus curiae in positive law has not been regulated explicitly or formally to explain how it is applied in criminal justice. While the judge plays a part in delivering a verdict on the defendant, it is anticipated to be founded on legal principles and a commitment of substantive public justice. This study employs a normative juridical research approach, utilizing secondary data acquired through library research and analyzed using qualitative methods and presented in a descriptive and explanatory format. The findings of this investigation that the position of amicus curiae can be known as stipulated in Article 5, paragraph (1) of the Judicial Power Act. In the application of the judge's decision to realize substantive justice, the judge does not only see a settlement in terms of formal law as a form of legal certainty, but the judge must also be able to see aspects of a sense of substantive justice by the expectations of the community as a seeker of justice.