bluuebunny/crossref_metadata_2025_split huggingface dataset:
Conductas sustentables en estudiantes de psicología: análisis comparativo por semestre de estudios, género, capacitación formal y ocupación
Authors: Galindo Ceja Ma de la Cruz , Duran Badillo Tirso , Vargas Ramos Catalina , Guerra Ordoñez Jesús Alejandro 
Published: January 2025

Objetivo: determinar si existen diferencias estadísticamente significativas en las conductas sustentables de los estudiantes de psicología, de acuerdo con el semestre en el que se encuentran, género, ocupación y capacitaciones formales previas. Metodología: Estudio descriptivo y comparativo en una muestra de 301 estudiantes del programa educativo de Licenciatura en Psicología, se aplicaron las escalas de indignación por daño ambiental, intención para actuar, afinidad por la diversidad, frugalidad o austeridad, altruismo y conducta pro ecológica general.
Resultados: No se presentaron diferencias estadísticamente significativas de acuerdo con el semestre en el que se encontraban estudiando (p>.05). Se observó mayor indignación por daño ambiental (p=.000) y mayor conducta proecológica general (p=.001) en el género femenino en comparación con el masculino. Los estudiantes que reportaron haber recibido algún tipo de capacitación sobre conductas sustentables resultaron con mayor intención para actuar (p=.000) y mayor conducta proecológica general (p=.017) en comparación con los que reportaron no haber recibido capacitaciones. Las conductas sustentables son similares entre los que estudian y los que estudian y trabajan (p>.05). Conclusiones: En el diseño de intervenciones para el desarrollo de conductas sustentables es importante considerar el género y las capacitaciones previas.
APPLICATION OF LEGO PLAY THERAPY TO REDUCE ANXIETY LEVELS IN PRESCHOOL CHILDREN DUE TO HOSPITALIZATION
Authors: Budiyati Budiyati , Firmansyah Bayu 
Published: January 2025

Anxiety is one of the responses of preschoolers who are undergoing hospitalization. Hospitalization often causes trauma to the child and sometimes makes the child cry, and refuses to cooperate during treatment. To overcome anxiety in preschoolers, the role of nurses in providing interventions must pay attention to the needs of children according to their growth and development. One of the activities to reduce anxiety in preschoolers is to provide lego play therapy. The purpose of proving EBNP by applying lego play therapy to reduce anxiety levels in preschool children in the age range of 3-6 years who are undergoing hospitalization. The design used is a descriptive method involving 3 respondents of preschool children, the instrument used is using the Preschool Anxiety Revised Scale (PASR) questionnaire. The action given is lego play therapy 6 times for 3 days with a duration of 20-30 minutes. The conclusion is that there is an effect of Lego play therapy on anxiety levels in children aged 3 – 6 years during hospitalization.
Pendidikan Agama dan Moral sebagai Alat Pencegahan Radikalisme
Authors: Virgana Virgana , Kasyadi Soeparlan 
Published: January 2025

Tujuan dari penelitian untuk mengkaji dampak perilaku warga negara Indonesia terhadap keamanan negara, terutama berfokus pada radikalisme di kalangan siswa SMA, penelitian ini untuk mengetahui pengaruh Pendidikan Agama dan Pendidikan Moral dengan menggunakan analisis jalur menggunakan Smart Partial Least Square (Smart-PLS) dengan ukuran sampel 1000 responden yang dipilih secara acak. Pengumpulan data dilakukan dengan menggunakan kuesioner untuk mengukur persepsi responden terhadap Pendidikan Agama (RE), Pendidikan Moral (ME), dan Pencegahan Radikalisme (RP). Kuesioner divalidasi melalui Exploratory Factor Analysis (EFA). Hasil yang diperoleh menunjukkan bahwa Pendidikan Agama secara langsung mempengaruhi Pencegahan Radikalisme, dengan Pendidikan Moral memainkan peran penting. Juga ditemukan bahwa ada keterkaitan antara dua variabel independen. Selain itu, temuan juga mengidentifikasi bahwa Pendidikan agama memberikan pengaruh tidak langsung pada Pencegahan Radikalisme, yang dimediasi melalui Pendidikan Moral di sekolah menengah. Berdasarkan hasil tersebut, disarankan agar pelaksanaan mata pelajaran Moral dan agama diwajibkan dari TK hingga SMA untuk semua siswa. .
Hands, Skills, Tools. Learning the Craft of Violin Making
Authors: May Sarah , Osner Sinah , Stransky Fabian , Wildhage Janine 
Published: January 2025

Violin makers are striving to create instruments of perfect sound and form. At this, they move between contradictive objectives: the canonized standards and one’s own creativity. The violin making schools occupy a powerful position in this negotiation process – while their attitudes, practices and objectives differ substantially. Accordingly, it is necessary to answer the question comparatively: How is violin making taught and learned in European schools at present and how do they respond to technical and cultural changes?
This volume explores parallels and differences between learning and teaching in the violin making schools in different European countries. In order to realize this work, the cooperation of a violin maker, a cultural anthropologist and two photographers proves to be as necessary as fruitful, since the implicit knowledge of the craftsmanship needs to be understood on the levels of observation, experience and dialogue against a culture-analytical background.
VNIIFTRI reference base in the field of underwater acoustic measurements: metrological characteristics, functional capabilities, innovations and prospects for improving standards
Authors: Isaev A. E. , Kuznetsov S. I. , Lomovatskiy Yu. A. , Matveev A. N. 
Published: January 2025

The updated VNIIFTRI’s underwater acoustic reference base is described. The article provides information about a special multifunctional metrological water tank, an underwater acoustic excess pressure tank, metrological characteristics of reference facilities of state primary standard of units of sound pressure and oscillating velocity in the water media GET 55-2017, state primary standard of the unit of ultrasound power in water GET 169-2019, state primary standard of the unit of sound velocity in liquid media GET 201-2012. A model of a hydrophone as an operational link and a minimum-phase four-terminal network is proposed, the concept of energy sensitivity in frequency bands is introduced, a method for determining the effective size of a hydrophone and obtaining its minimum-phase frequency response of sensitivity is proposed, implemented in GET 55-2017. A method for representing the complex frequency response of sensitivity by a formula is proposed, and requirements for the functionality of a digital metrology platform are formulated. GET 169-2019 is supplemented with two facilities for reproducing units of intensity and pressure of ultrasound in water, which will make it possible to find a comprehensive solution to the problem of metrological support for ultrasound medical and other equipment manufactured and used in Russia. GET 201-2012 is supplemented with a facility for reproducing and transmitting the unit of sound velocity in water using the time-of-flight pulse method with a variable base. The change in the base length is measured using the optical interference method, and the time delay is measured using characteristic points of pulse signals. Prospects for improving primary standards are discussed. Attention is drawn to the problems that have arisen in the participation of the Russia in international comparisons and possible ways to solve them.
Analisis Bukti Digital Untuk Penanganan Kekerasan Berbasis Gender Online Pada Media Sosial Whatsapp Menggunakan Metode National Institute Of Justice (NIJ)
Authors: Sinusi Isnan , Salim Yulita , Alwi Erick Irawadi 
Published: January 2025

Kekerasan Berbasis Gender Online (KBGO) adalah bentuk tindakan kriminal yang membuat seseorang merasa tidak aman atau menyerang gender seksualitas seseorang dengan difasilitasi oleh internet serta teknologi. Salah satu bentuk KBGO yaitu pelecehan seksual (sexual harassment).Berdasarkan Catatan Tahunan Komnas Perempuan yang dirilis pada 5 Maret 2021, terdapat 940 kasus KBGO dari sebelumnya 281 kasus sepanjang 2020. Dari banyaknya kasus tersebut mayoritas bentuk pelecehan yang dilakukan berupa ancaman untuk menyebarkan media tak senonoh (37,5%), pornografi balas dendam (15%), dan penuntutan gambar atau video tak senonoh (10,4%). Salah satu teknologiyang dijadikan media untuk komunikasiadalah Aplikasi Whatsapp. WhatsappMessenger adalah layanan komunikasi pertukaran pesan di smartphone berbasis Android. Kelengkapan fitur yang dimiliki Whatsapp memaksimalkan pengalaman pemanfaatan teknologi bagi pengguna secara umum yang dapat dimanfaatkan para pelaku kejahatan. Salah satunya yaitu Tindakan pelecehan seksual. Fitur penghapusan pesan hingga penghapusan riwayat panggilan dapat menjadi salah satu fitur yang dimanfaatkan pelaku kejahatan untuk menyembunyikan atau menghilangkan bukti digital. Oleh karena itu dibutuhkan protokol tertentu yang dapat membantu pihak berwajib untuk memeriksaatau menganalisa bukti digital yang telah berusaha dihilangkan oleh pelaku kejahatan pelecehan seksual. Metode yang digunakan untuk melakukan pemeriksaan pada barang bukti digital dalam konteks hukum adalahForensik digital. Penelitian ini melakukan skenario akuisisi bukti digital pada aplikasi Whatsapp berbasis Android dengan menerapkanmetode NIJ dalam tahapan proses investigasi barang bukti digital untuk mendapatkan barang bukti digital tersebut hingga menyimpulkan hasil bukti digital yang didapatkan. Dari hasil penelitian didapatkan berupa bukti fisik berupa 1 unit smartphone berbasis Android dilakukan proses penghilangan jangkauan sinyal dengan mengaktifkan airplane mode. Sementara itu, Proses Akuisisi Smartphone 1 dilakukan menggunakanMagnet Axiom dan MOBILedit Forensic Express dengan mengkoneksikannya ke Laptop Merk Asus ROG Strix G17, OS Windows 10 64 bit. Pada Smartphone 1 juga dilakukan pemeriksaan berdasarkan prosedur metode NIJ ditemukan informasi terkait aplikasi yang digunakan yaituWhatsApp Messenger dan menemukan chat, dan gambar yang dikirimkan kepada korban.
METODE SUPPORT VECTOR MACHINE UNTUK KLASIFIKASI DATA PENYAKIT HATI YANG IMBALANCE
Authors: Rahmah Nur , Purnawansyah Purnawansyah , Umar Fitriyani 
Published: January 2025

Penelitian ini bertujuan untuk melakukan klasifikasi penyakit hati menggunakan metode Support Vector Machine (SVM) dan Synthetic Minority Oversampling Technique (SMOTE). Data yang digunakan berupa data sekunder yang diperoleh dari situs Kaggle dengan jumlah data sebanyak 582 sampel. Data tersebut terdiri dari 10 fitur yang digunakan sebagai variabel masukan SVM. Proses klasifikasi dilakukan dengan membagi data menjadi data training 70% dan data testing 30%. Hasil dari penelitian yang telah dilakukan ialah dengan menggunakan metode support vector machine mampu melakukan klasifikasi data penyakit hati dengan hasil klasifikasi yang menunjukkan nilai 0 dan 1. Dimana nilai 0 menandakan bahwa pasien tersebut tidak mengidap penyakit hati dan nilai 1 menandakan bahwa pasien tersebut mengidap penyakit hati. Berdasarkan proses klasifikasi data penyakit hati yang telah dilakukan memperoleh nilai akurasi performansi yaitu 67,06%, dan berdasarkan proses visualisasi data yang telah dilakukan dalam proses pengklasifikasian data tersebut ditemukan ketidakseimbangan data penyakit hati. Ketidakseimbangan data yang peroleh dilakukan oversampling menggunakan metode SMOTE untuk menyeimbangkan data. Penelitian telah melakukan proses penyeimbangan data penyakit hati sehingga tenaga menis lebih terbantukan dalam mendeteksi penyakit hati yang diderita oleh pasien
Associations between left atrial indices and cardiorespiratory and muscular fitness among physically active military personnel
Authors: Lin Yen-Chen , Liu Pang-Yen , Tsai Kun-Zhe , Huang Wei-Chun , Yu Wen-Chung , Sui Xuemei , Lavie Carl J. , Lin Gen-Min 
Published: January 2025

BackgroundLeft atrial (LA) size and function are linked to exercise intolerance in heart failure, while associations between LA parameters and exercise performance remain unclear in athletes.ObjectivesThis study aimed to identify correlations between echocardiographic LA size, pressure, stiffness, and composite indices, and various exercise performance indicators.MethodsEchocardiographic parameters were obtained from 181 physically active military personnel receiving regular training and tests for a 3-km run and 2 min of push-ups and sit-ups. The top 16% of runners were compared sex-specifically, with the remaining 84% as controls to identify LA discriminators for running capacity. LA composite indices were defined as the LA volume index (LAVI) divided by the stiffness index (LASI) or pressure index (mitral E/e′). Spearman correlations were used to identify LA correlates with exercise performance. Generalized linear regressions were used to identify LA predictors of exercise performance with adjustments for potential covariates.ResultsThe top 16% of runners vs. controls had a lower LASI based on LA volume changes (LASI_v, 0.196 vs. 0.245, p = 0.013) and higher LAVI-to-LASI_v (12.30 vs. 8.08, p = 0.001) and LAVI-to-(mitral E/e′) (4.37 vs. 3.76, p = 0.038) ratios. The LAVI-to-LASI_v ratio was the most highly correlated shared LA parameter for running (|rho| = 0.403), push-up (rho = 0.335), and sit-up (rho = 0.352) performance. The LAVI-to-mitral E/e′ ratio was the most highly correlated, independent, and unique LA parameter for running (|rho| = 0.457) performance.ConclusionsThe LAVI-to-LASI_v ratio, comprising LA size and stiffness information, was the best correlate across exercise types, while the LAVI-to-mitral E/e′ ratio, comprising LA size and pressure information, was the best correlate of an endurance exercise, i.e., 3-km running performance.
Case Report: Surgery combined with extracorporeal membraneoxygenation for acute type A aortic dissection complicated with acute myocardial infarction
Authors: Xia Jianming , Qiu Yan , Chang Shuo , Feng Ying , Zhang Heng , Wang Xiaoqi 
Published: January 2025

BackgroundAcute myocardial infarction (AMI) is one of the most serious complications of acute type A aortic dissection (ATAAD) and markedly increases patient mortality. Simultaneous treatment strategies remain controversial. How to improve the treatment of these patients remains a critical challenge for cardiovascular surgeons.Case presentationAll three patients who experienced chest pain were admitted to emergency department of our hospital. The 12-lead electrocardiogram revealed ST-segment depression, myocardial enzyme levels were significantly elevated. Emergency physicians diagnosed ATAAD with AMI, and emergency surgery was planned in collaboration with the cardiovascular surgery team. One-stage surgery for coronary revascularization and central aortic repair were performed, extracorporeal membrane oxygenation (ECMO) was implanted, ECMO was discontinued when hemodynamics stabilized. The patient ultimately recovered well and was discharged.ConclusionFor ATAAD combined with right ventricular AMI, one-stage surgery for coronary revascularization and central aortic repair, supported by ECMO as bridge, can be life-saving treatment strategy, the prognosis for all three patients was excellent.
Sex differences in cardiorespiratory control under hypoxia: the roles of oxygen desaturation and hypoxic exposure time
Authors: Oliveira André Luiz Musmanno Branco , Rodrigues Gabriel Dias , Silva Bruno Moreira , Rohan Philippe de Azeredo , Soares Pedro Paulo da Silva 
Published: January 2025

IntroductionMales and females differ anatomically and functionally in cardiorespiratory regulation, with males tending to experience greater oxygen desaturation under hypoxia. Therefore, sex might moderate cardiorespiratory responses to acute hypoxia exposure. Accordingly, we hypothesized that sex differences in cardiovascular and ventilatory responses would be more pronounced with equal hypoxia duration (iso-time) but less pronounced at similar oxygen desaturation levels (iso-saturation).MethodsTwenty-two (12 females) healthy individuals were exposed to normoxia (10 min at FiO2 = 0.21) and hypoxia (10 min at FiO2 = 0.115), respectively. Pulse oxygen saturation (SpO2), R-R intervals, cardiac output, blood pressure (BP), and ventilatory data were continuously recorded during spontaneous breathing. Spectral analysis of R-R intervals and systolic BP revealed cardiovascular autonomic modulation in the low- (LF; 0.04–0.15 Hz) and high-frequency (HF; 0.15–0.40 Hz) bands and alpha-index (α–LF) assessed spontaneous baroreflex sensitivity (BRS). Sex differences were compared in iso-saturation and iso-time analyses.ResultsAt 10 min of hypoxia (iso-time), males desaturated more than females (interaction: p = 0.004), and hypoxia-induced tachycardia in both groups (p &lt; 0.001), but no “sex-time” interaction was found for cardiovascular data. In contrast, only males responded with ventilatory responses during iso-time hypoxia, decreasing breathing frequency (interaction: p = 0.022) and increasing tidal volume (Vt) (interaction: p = 0.036). Otherwise, during iso-saturation (SpO2-matched ∼91%), heart rate and LF of R-R intervals increased more in females than in males (interaction: p = 0.049). However, only males increased Vt (interaction; p = 0.037).ConclusionOur data indicate that females counterbalance hypoxia mainly by systemic circulatory adjustments, while males use both, circulatory and ventilatory adjustments.
Impact of strict IGF1 control on quality-of-life scores in patients with acromegaly
Authors: Gandhi Chaitanya , Denis Marie-Claire , Holmes Daniel , Rivera Juan , van Uum Stan , Ezzat Shereen , Chik Constance 
Published: January 2025

ObjectiveExamine, in a real-world setting, whether strict normalization of modestly elevated insulin-like growth factor 1 (IGF1) results in clinical and health-related quality of life benefits in patients with acromegaly using an open-label, non-randomized, 6-month prospective interventional study.MethodsIn patients with acromegaly and modest IGF1 elevation, strict IGF1 control was achieved by addition or dose escalation of pegvisomant. Clinical and biochemical parameters were assessed at baseline, 1 and 3 months for pegvisomant dose titration, and at 6 months. The Patient-Assessed Acromegaly Symptom Questionnaire (PASQ), the Acromegaly Quality of Life questionnaire (AcroQoL) and the Acromegaly Disease Activity Tool (ACRODAT®) were completed at baseline and at 6 months.ResultsTen patients (8 males) with mean age of 50.7 years participated in the study. All patients had a macroadenoma and nine had prior transsphenoidal surgeries. At time of screening, six patients were on a somatostatin analog, two on pegvisomant, and two on pegvisomant and a somatostatin analog. After six months of dose escalation or the addition of pegvisomant, IGF1 decreased from 1.22 ± 0.14 to 0.87 ± 0.20 times the upper limit of normal (p=0.001). PASQ score decreased by 3.5 (p=0.02) and the ACRODAT® overall status decreased by 50.5 (p=0.001); however, there was no difference in the AcroQoL score. Hemoglobin A1c and liver enzymes did not differ and repeat MRI of the sella at 6 months showed no change.ConclusionsIn this pilot study, stricter control of modest IGF1 elevations led to symptomatic improvement as measured by the PASQ score. These findings prompt larger prospective trials.
Molecular genetic analysis of Rubinstein–Taybi syndrome in Russian patients
Authors: Ismagilova Olga R. , Adyan Tagui A. , Beskorovainaya Tatiana S. , Polyakov Alexander V. 
Published: January 2025

IntroductionRubinstein–Taybi syndrome (RSTS) is one of the many forms of syndromic intellectual disability, occurring in the population with a frequency of 1: 100–125 thousand newborns. The specific phenotype of patients enables the so-called “portrait” diagnosis of classical cases of RSTS, followed by the analysis of the CREBBP and EP300 genes, whose association with RSTS has been confirmed. Nevertheless, for approximately half of the patients in various cohorts, the diagnosis cannot be confirmed.MethodsIn this paper we present the results of a study of 158 Russian patients referred for molecular diagnosis of RSTS using multiplex ligation-dependent probe amplification (MLPA) and next-generation sequencing (NGS).ResultsPathogenic and likely pathogenic variants were identified in 67 patients (42.4%), of which 62 (39%) were in CREBBP and 4 cases (2%)—in EP300. In one case, a known pathogenic variant in SRCAP, associated with Floating–Harbor syndrome (FHS), which is phenotypically similar to RSTS, was also identified; therefore, the possibilities and prospects for differential diagnosis were considered.
Gene prediction of immune cells association between gut microbiota and colorectal cancer: a Mendelian randomization study
Authors: Zhong Yan , Chen Guanglei , Chen Menglu , Cui Junsong , Tan Qianren , Xiao Zhenghua 
Published: January 2025

BackgroundAn increasing number of studies have revealed that gut microbiota influences the development and progression of Colorectal cancer (CRC). However, whether a causal relationship exists between the two remains unclear, and the role of immune cells in this context is not well understood.ObjectiveTo elucidate the causal relationship between gut microbiota and CRC and to explore the potential mediating role of circulating immune cells.Materials and methodsTo analyze the causal relationship between gut microbiota and CRC, we employed a univariable Mendelian randomization (UVMR) approach. Subsequently, a two-step multivariable Mendelian randomization (MVMR) to assess the potential mediating role of circulating immune cells. Primarily, applied the Inverse-Variance Weighted method to evaluate the causal relationship between exposure and outcome. To ensure the robustness of the results linking gut microbiota and CRC, we validated the findings using Robust Inverse-Variance Weighted, Penalized Inverse-Variance Weighted, and Penalized Robust Inverse-Variance Weighted methods. Additionally, we employed MR-Egger Intercept to mitigate the influence of horizontal pleiotropy. MR-PRESSO was used to detect and correct outliers by excluding anomalous instrumental variables. Finally, we supplemented our analysis with methods such as Bayesian Weighted Mendelian Randomization (BWMR), Maximum-Likelihood, Lasso, Debiased Inverse Variance Weighted, and Contamination Mixture to establish a robust and compelling causal relationship.ResultsAfter accounting for reverse causality, horizontal pleiotropy, and various methodological corrections, Bifidobacterium kashiwanohense, GCA-900066755 sp900066755, Geminocystis, and Saccharofermentanaceae exhibited strong and robust causal effects on CRC. Specifically, CD40 on monocytes (2.82%) and CD45 on CD33+HLA-DR+CD14- cells (12.87%) mediated the causal relationship between Bifidobacterium kashiwanohense and CRC risk. Furthermore, CD45 on CD33-HLA-DR+ (3.94%) mediated the causal relationship between GCA-900066755 sp900066755 and CRC risk. Additionally, terminally differentiated CD4+T cells (11.55%) mediated the causal relationship between Geminocystis and CRC risk. Lastly, CD40 on monocytes (2.35%), central memory CD4+T cells (5.76%), and CD28 on CD28+CD45RA+CD8+T cells (5.00%) mediated the causal relationship between Saccharofermentanaceae and CRC risk.ConclusionOur mediation MR analysis provides genetic evidence suggesting that circulating immune cells may mediate the causal relationship between gut microbiota and CRC. The identified associations and mediation effects offer new insights into potential therapeutic avenues for CRC.