bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metallothionein as a biomarker for mercury in tissues of rat fed orally with cinnabar
Authors: Huang Zhi‐Yong , Shen Jin‐Can , Zhuang Zhi‐Xia , Wang Xiao‐Ru , Lee Frank S. C. 
Published: May 2004

AbstractCinnabar, as one of the most widely used mineral drugs in traditional Chinese medicines, has been proven to have prominent curative effects in clinical use for more than 2000 years. But the safety and toxicity of the drug has been under constant debate in clinic usage. Metallothionein (MT) contains about 30% of cysteine in the molecule, and plays an important detoxification role against heavy metals. In this study, it was used as a biomarker to assess mercurial accumulation in rats fed orally with cinnabar. After feeding rats with cinnabar by gastric gavage at different dosages and at different times, the distribution of heavy metals (including mercury, copper and zinc) and MT was investigated among rat tissues, including liver, kidney, heart, brain, testis and blood. Metals and MT determinations were carried out using inductively coupled plasma mass spectrometry (ICP‐MS) and a modified mercury saturation assay technique respectively. The results indicated that mercury was easily accumulated in the tissues of rats exposed to cinnabar, especially in kidney. For example: at a feeding dosage of 5 g kg−1 (bw) for 4 weeks, the mercury concentrations in kidney were 13, 8.7, 21.6 and 26 times those in liver, testis, brain and heart respectively; and at 2.5 g kg−1 (bw) for 2 weeks, the mercury concentrations in kidney were 21, 2.1, 3 and 21 times those in liver, testis, brain and heart respectively. In addition, mercury in kidney and liver of all cinnabar groups was significantly higher than that of the control group (P < 0.01). A high positive correlation observed between MT concentrations and mercury levels in both liver and kidney (R2 = 0.9299, P < 0.02 for liver; R2 = 0.9923, P < 0.0008 for kidney) indicated that MT could be used as a biomarker for mercury in tissues. Copyright © 2004 John Wiley & Sons, Ltd.
Should we be using bilateral carotid distal protection devices during the percutaneous closure of patent foramen ovale in patients with a history of paradoxical embolus?
Authors: Richardson Gail , Keeble Thomas R. , Rothman Martin T. 
Published: May 2004

AbstractPercutaneous closure of patent foramen ovale (PFO) is becoming standard practice, particularly in patients with a history of embolic phenomena. The acute risk of cerebrovascular accident in patients undergoing this procedure is ∼ 1%. We report the first successful use of bilateral carotid artery distal protection in this situation. Catheter Cardiovasc Interv 2004;62:272–275. © 2004 Wiley‐Liss, Inc.
Intra‐arterial thrombolysis for left middle cerebral artery embolic stroke during percutaneous mitral commissurotomy
Authors: Vijayakumar M. , Rajesh T. , Kumar Prasanna , Haridas K.K. 
Published: May 2004

AbstractCerebral thromboembolism is a serious complication. Early recognition and rapid reperfusion can prevent long‐term neurological morbidity. We report a case of successful intra‐arterial thrombolysis for middle cerebral artery embolic stroke during percutaneous mitral commissurotomy, which resulted in complete neurological recovery. Catheter Cardiovasc Interv 2004;62:249–251. © 2004 Wiley‐Liss, Inc.
Early ostial saphenous vein graft stenosis associated with the use of Symmetry sutureless aortic proximal anastomosis device: Successful percutaneous revascularization
Authors: Cline Sharon L. , Guduvalli Anuradha , Kalaria Vijay G. 
Published: May 2004

AbstractA recent advance in technology permits the creation of sutureless proximal aortic anastomosis during coronary artery bypass graft surgery. This new tool has significant potential benefit by minimizing aortic manipulation with subsequent reduction in neuroembolization. Implantation of a nitinol‐based proximal aortic connector (Symmetry) has a potential to elicit intimal hyperplastic reaction analogous to restenosis after coronary stent placement. We report cases of early vein graft stenosis in association with the use of the Symmetry device. Three patients suffered from severe ostial stenosis within 6 months of bypass surgery with symptomatic presentation. Of these three patients, two underwent successful percutaneous revascularization. Fluoroscopic star‐shaped appearance of the metallic Symmetry allows device recognition during angiography. We review current data regarding graft patency with the use of Symmetry device and discuss technical issues to address specific problems during percutaneous revascularization. Catheter Cardiovasc Interv 2004;62:203–208. © 2004 Wiley‐Liss, Inc.
Novel use of a high‐energy excimer laser catheter for calcified and complex coronary artery lesions
Authors: Bilodeau Luc , Fretz Eric B. , Taeymans Yves , Koolen Jacques , Taylor Kevin , Hilton David J. 
Published: May 2004

AbstractThis study was designed to evaluate safety and effectiveness of the 0.9 mm excimer laser coronary catheter with increased laser parameters. We report a prospective trial of 100 calcified and/or balloon‐resistant lesions where a new 0.9 mm excimer laser catheter was used at standard or higher energy level to facilitate angioplasty. Standard in‐hospital clinical and angiographic parameters were collected and measured. Laser technical success was obtained in 87 lesions (92%), procedural success was reached in 88 lesions (93%), and clinical success in 82 lesions (86%). Increased laser parameters were used for 29 resistant lesions. This new 0.9 mm excimer laser coronary catheter using higher energy parameters seems to be safe and effective for management of calcified and nondilatable lesions. Catheter Cardiovasc Interv 2004;62:155–161. © 2004 Wiley‐Liss, Inc.
Aortic aneurysm repair with endovascular grafts: Developing a graft surveillance program
Authors: Slovut David P. , Bacharach J. Michael 
Published: May 2004

AbstractThe objective of this study was to describe the development of a comprehensive surveillance program for monitoring the long‐term follow‐up of endoluminal stent graft (ELG) patients. Despite high procedural success rates, ELG patients remain at ongoing risk for aneurysm sac expansion, rupture, and other adverse events that make long‐term surveillance imperative. As they perform more ELG, practitioners face increased logistical difficulty performing appropriate patient follow‐up. A computer‐based data ELG registry was created using Epi Info, a program developed by the Centers for Disease Control and Prevention that enables users to design a data entry form, enter data, and perform statistical analyses. The database has been used to track 259 patients (214 men and 45 women) who underwent ELG between November 1999 and October 2003. One‐year follow‐up was available for 182 patients, 2‐year follow‐up for 104 patients, and 3‐year surveillance data for 40 patients, which represent follow‐up rates of 89.6%, 78.8%, and 61.5%, respectively. There were 25 late deaths. The Kaplan‐Meier estimate for 1‐year survival was 92.5%. Twenty‐one patients underwent 24 secondary angiographic procedures at a mean 8.6 ± 10.3 months (range, 1–37.6) after stent‐graft repair. No mortality was observed in association with a secondary intervention. There were no late conversions to open aneurysm repair. The Kaplan‐Meier estimate for freedom from secondary intervention for all patients at 1 year was 91.0%. A computer‐based registry facilitates appropriate and timely patient follow‐up and may improve the long‐term outcome from ELG. Catheter Cardiovasc Interv 2004;62:252–261. © 2004 Wiley‐Liss, Inc.
Growth of Ba2Re(Y,Pr)Ru1‐xCuxO single crystals in a high temperature solution drop using an infrared imaging system
Authors: Rao S. M. D. , Lin B. H. , Lu C. Y. , Sutanto N. , Liao Y. C. , Wu M. K. 
Published: May 2004

AbstractInfrared imaging furnace was used to grow single crystals of Ba2YRu1‐xCuxO6 and Ba2PrRu1‐xCuxO6 using high temperature solutions of PbO‐PbF2 in the form of a bubble attached to the feed rods. Several small crystals were found deposited on the cooler portions of the sintered rod as well as in the drop like portion at the end of the rod. These crystals were collected and the morphology, microstructure and magnetic properties were studied. The details of these investigations are presented. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Growth of near‐stoichiometric LiNbO3 crystals and Li2O contents determination
Authors: Sun D. L. , Hang Y. , Zhang L. H. , Luo G. Z. , Zhu S. N. , Lim P. K. , Hung W. W. 
Published: May 2004

AbstractTwo kinds of near‐stoichiometric LiNbO3 crystals (SLN11 and SLN19) were grown by a flux pulling method from stoichiometric melt with addition of 11mol%K2O and 19mol%K2O, respectively. Compared with the congruent melting LiNbO3, the ultraviolet absorption edges of two crystals shift towards shorter wavelengths, and the locations of the OH‐ infrared absorption band have obvious change and the bandwidths become greatly narrower. From these experimental results, the Li2O contents are determined indirectly to be about 49.6mol% for SLN11 and 49.9mol% for SLN19, respectively. The Li2O content in SLN19 is very close to the ideal value of 50mol%. The coercive fields of two crystals were measured by the poling method at room temperature. A linear relationship between the Li2O content and the coercive field was fitted. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Thermal conductivity of ZnSe by molecular dynamics simulation
Authors: Balasubramanian A. K. , Sankar N. , Ramakrishnan S. K. , Ramachandran K. 
Published: May 2004

AbstractMolecular dynamics simulation using the new fit of the empirical Tersoff Potential is applied to study the thermal properties of ZnSe at and below the room temperature. The resulting diffusivity and thermal conductivity are compared with the photoacoustic measurements on the grown ZnSe crystal. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Beamforming array antenna with heterogeneous signal distribution for UWB pulse transmission
Authors: Sato Tadatomo , Abreu Giuseppe , Kohno Ryuji 
Published: May 2004

AbstractAs ultra‐wideband (UWB) is a technology primarily aimed at short‐range communications, it is expected that in many UWB networks transmitters and receivers are concentrated in close proximity. Mutual interference among UWB devices is therefore a key problem to be overcome. One effective method to achieve this goal is the application of spatial division techniques using array antennas, which can have modified radiation patterns modified adaptively. UWB impulse radio systems, however, employ the transmission of baseband (carrierless) signals. This peculiarity of UWB‐IR systems makes the straightforward application of conventional beamforming methods, which are based on the control of amplitudes and phases of the signals transmitted from each element in the array, a rather difficult problem. In this paper a new beamforming method is proposed, which is based on the control of the power intensity profile of the frequency components shared by signals transmitted simultaneously from several antenna elements. In order to demonstrate the effectiveness of the method, computer simulations are shown which demonstrate that if a monocycle waveform is divided into several signals representing overlapping frequency subband components of the original, each transmitted from a different antenna element, a radiation pattern without sidelobes can be synthesized over the UWB. © 2004 Wiley Periodicals, Inc. Electron Comm Jpn Pt 3, 87(11): 1–10, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/ecjc.20074
Comparative study of electron density profiles in compact torus plasma merging experiments
Authors: Hayashiya Hitoshi , Asaka Takeo , Katsurai Makoto 
Published: May 2004

AbstractFollowing two previous papers on comparative studies of the electron density distributions for a single compact torus (CT) and a spherical tokamak (ST), and for a single ST and a merged ST, a comparative study on the dynamics of the electron density profile during and after the CT and ST plasma merging process was performed. The sharpness of the peak in the electron density profile around the midplane just after the merging of CT with a low safety factor (q value) such as RFP or spheromak is found to be related to the speed of the magnetic axis during the plasma merging process. It is also found that the electron density gradient near the plasma edge in a high‐q ST is larger than that of a low‐q CT. High‐q ST is found to have a magnetic structure which is able to sustain a large thermal pressure by a strong j × B force. Despite these differences in the electron density profile between CT and ST during merging, the confinement characteristics evaluated from the number of electrons confined within the magnetic separatrix after the completion of the merging are almost similar between the merging CT and the merging ST. For all configurations, the electron density profiles after the completion of the merging are analogous to those of the corresponding single configuration produced without the merging process. © 2004 Wiley Periodicals, Inc. Electr Eng Jpn, 148(2): 14–21, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.10312
Numerical simulation of blow‐down closed‐cycle disk MHD generator
Authors: Inui Yoshitaka , Ito Hideyuki , Ishida Taichi 
Published: May 2004

AbstractNumerical simulations of the closed‐cycle disk MHD generation experiment with Tokyo Institute of Technology's Fuji‐1 blow‐down facility are performed. In the calculations, the r–z two‐dimensional time‐dependent simulation code developed by the authors that can take the effect of water contamination into account is used, and the experimental conditions of Run A4109 operated by Disk‐F4 generator are selected as the numerical conditions. When the water contamination is the lowest level realized in the experiments, the simulation results coincide with the experimental results reasonably well, though there exist some discrepancies caused by inaccuracy of used basic plasma parameters, limitations of the two‐dimensional approximation, and so on. The voltage–current curve is almost linear, indicating that the MHD interaction is relatively weak and the flow field is mainly determined by the back‐pressure. The increase of the water contamination level results in decreased seed ionization rate at the generator channel inlet, leading to the steep deterioration of the generator performance. © 2004 Wiley Periodicals, Inc. Electr Eng Jpn, 148(2): 46–54, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.10335
Magnetostriction and motor vibration
Authors: Kamimoto Katsumi , Ishibashi Fuminori , Noda Shinichi , Yanase Shunji , Sasaki Tadashi 
Published: May 2004

AbstractA quiet induction motor is strongly demanded today. Electromagnetic factors are a main cause of vibration and acoustic noise in a small induction motor. Electromagnetic forces and magnetostrictive forces are considered as the origin of electromagnetic vibration and noise. In this paper, magnetostrictive vibration of a ring of electrical steel sheets was simulated by the mechanical finite element method. Magnetostriction was assumed as external forces and they were added at each node of the meshed ring. Resonant frequency and the mode of the ring were calculated. In the steel sheet ring excited by a PWM voltage source inverter, the frequency spectrum of vibration of ring was measured and compared with the calculated results. It was confirmed that these procedures simulated magnetostriction behavior of electrical steel sheets. Furthermore, the electromagnetic forces of a small induction motor were calculated and compared with the magnetostriction data. It became clear that electromagnetic vibration was affected by the magnetostriction of steel. These results will be useful in the reduction of acoustic noise and the development of quiet motors. © 2004 Wiley Periodicals, Inc. Electr Eng Jpn, 148(2): 8–13, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.10338
Development of a high‐speed laser interferometer using an acousto‐optic deflector
Authors: Fukuchi Tetsuo , Nayuki Takuya , Nemoto Koshichi , Uchino Kiichiro 
Published: May 2004

AbstractAn acousto‐optic laser deflector was used as a shutter for high‐speed imaging of laser interference fringes using an ordinary CCD camera. The exposure duration was set by the pulse width of the high‐frequency signal applied to the acousto‐optic deflector. Changes in laser interference fringes due to an impulse discharge in air were obtained at an exposure duration of 4 µs. By applying a sequence of high‐frequency signals with different frequency, the beam was deflected to four different angles at different times, allowing four interference images to be captured on a single video frame. This was used for time‐resolved imaging of the interference fringe pattern. © 2004 Wiley Periodicals, Inc. Electr Eng Jpn, 148(2): 76–83, 2004; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20011
Enantioselective Recognition of Amino Acid by Differential Pulse Voltammetry in Molecularly Imprinted Monolayers Assembled on Au Electrodes
Authors: Huan Shuangyan , Shen Guoli , Yu Ruqin 
Published: May 2004

AbstractAn electrochemical sensor based on L‐cysteine SAM imprinted by L‐serine has been developed for the detection of L‐serine. The sensor shows some entantioselectivity toward L‐serine and a stable response establishes within 5 min. The peak current intensity of potassium ferricyanide quantified by differential pulse voltammetry (DPV) decreased linearly with increasing L‐serine concentration from 10 to 100 μM with a gradient of 20.91 nA μM−1. The detection limit was 4.32 μM. The coefficient of enantiometric selectivity of the molecularly imprinted SAM was about 3.0. Compounds with similar structure as serine caused much less response.
A Novel Sulfate Polymeric Membrane Sensor Based on a New Bis‐Pyrylium Derivative
Authors: Ganjali Mohammad Reza , Shirvani‐Arani Simindokht , Nourozi Parviz , Salimzadeh Davood , Faal‐Rastegar Madjid , Moghimi Abolghasem 
Published: May 2004

AbstractA novel ion‐selective polymeric membrane sensor based on pyrylium‐4,4‐(1,4‐phenylen) bis[2,6‐bis(2‐naphthyl)]‐bis[tetrafluoroborate] (PBGNB) as an excellent sensing material is successfully developed. The electrode possesses the advantages of a very low detection limit (5.0×10−8 M), a wide working concentration range (1.0×10−8−1.0×10−1 M) and specially, a high sulfate selectivity over most common organic and inorganic anions. The sensor displays Nernstian behavior (slope of 29.5±0.5 mV per decade) in a wide pH range (3.0–8.5). It shows a short response time in the whole concentration range (ca. 10 s). The electrode was used as an indicator electrode in the potentiometric titration of sulfate ions with barium ions. The proposed sensor was successfully applied to the direct determination of salbutamol sulfate and paromomycin sulfate.
Effects of hydrogen peroxide on light emission by various strains of marine luminescent bacteria
Authors: Katsev Andrey M. , Węgrzyn Grzegorz , Szpilewska Hanna 
Published: May 2004

AbstractLight‐emitting bacteria are the most abundant and widespread luminescent organisms. Most species of such bacteria live in marine environments. However, until recently, biological role of bacterial luminescence remained unknown. Recent studies indicated that light produced in bacterial cells may stimulate DNA repair. Therefore, it is not surprising that agents that cause DNA damage induce expression of lux genes. Moreover, it was proposed previously that bacterial luciferases may be involved in detoxification of reactive oxygen species. Recently, this hypothesis was confirmed experimentally. Here we investigated effects of hydrogen peroxide on light emission by various strains of luminescent bacteria. We found that luminescence of strains with luciferase of fast kinetics of reaction decreased at considerably lower concentrations of H2O2 than that of strains with luciferase of the slow kinetics. The action (either direct or indirect) of luciferases as anti‐oxidants seemed to be independent of activity of catalase, which was found to be different in various strains. Therefore, it seems that luciferases of the slow kinetics are more efficient in detoxification of reactive oxygen species than those of the fast kinetics. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)
Cytosolic NADP phosphatases I and II from Arthrobacter sp. strain KM: Implication in regulation of NAD+/NADP+ balance
Authors: Kawai Shigeyuki , Mori Shigetarou , Mukai Takako , Murata Kousaku 
Published: May 2004

AbstractNADP phosphatase (NADPase) is an enzyme that converts NADP+ into NAD+ through dephosphorylation of NADP+, and is considered to be one of the possible candidates for regulation of the NAD+/NADP+ balance in vivo. In order to obtain an intrinsic NADPase, the NADP+‐degrading activity in a membrane‐free cell extract of a Gram‐positive bacterium, Arthrobacter sp. strain KM, was first assessed and demonstrated to be mainly achieved through the NADPase reaction, indicating NADPase is essential for degradation of NADP+ and therefore for regulation of the NAD+/NADP+ balance in cytosol. Then, the isolation of cytosolic NADPase was attempted using NADP+ as a substrate. Two NADPase isozymes, designated as NADPases I and II, were purified from the cell extract of the bacterium, and were indicated to be the sole cytosolic NADPases regulating the balance of NAD+/NADP+. NADPases I and II are homodimers of 32 and 30 kDa subunits, respectively, and most active at pH 7–8. The N‐terminal amino acid sequences of the two enzymes are similar to each other. Among the biological substrates tested, both enzymes showed the highest activity toward NADP+ and NADPH. AMP, ADP, and pyridoxal 5′‐phosphate were also dephosphorylated, but to lower extents. Comparison of the features of NADPases I and II with those of other acid phosphatases possessing NADPase activity suggested that NADPases I and II are novel enzymes participating in regulation of the NAD+/NADP+ balance in the cytosol. (© 2004 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)