bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mixed Methods Evaluation of the ‘Caring for Providers to Improve Patient Experience’ intervention
Authors: Afulani Patience A. , Getahun Monica , Okiring Jaffer , Ogolla Beryl A. , Oboke Edwina N. , Kinyua Joyceline , Oluoch Iscar , Odiase Osamuedeme , Ochiel Dan , Mendes Wendy Berry , Ongeri Linnet 
Published: October 2023

AbstractObjectiveTo assess the impact of the “Caring for Providers to Improve Patient Experience (CPIPE)” intervention, which sought to improve person-centered maternal care (PCMC) by addressing two key drivers—provider stress and bias.MethodsCPIPE was successfully piloted over 6-months in two health facilities in Migori County, Kenya in 2022. The evaluation employed a mixed-methods pretest-posttest-non-equivalent-control-group design. Data are from surveys with 80 providers (40 intervention; 40 control) at baseline and endline, and in-depth-interviews with 20 intervention providers. We conducted bivariate, multivariate, and difference-in-difference analysis of quantitative data and thematic analysis of qualitative data.ResultsIn the intervention group, average knowledge scores increased from 7.8(SD=2.4) at baseline to 9.5(SD=1.8) at endline for stress(p=0.001), and from 8.9(SD=1.9) to 10.7(SD=1.7) for bias(p=0.001); perceived stress scores decreased from 20.9(SD=3.9) to 18.6(SD=5.3)(p=0.019), and burnout from 3.6(SD=1.0) to 3.0(SD=1.0)(p=0.001); with no significant change in the control group. Qualitative data indicated CPIPE had impact at multiple levels. At the individual level, it improved provider knowledge, skills, self-efficacy, attitudes, behaviors, and experiences. At the interpersonal level, it improved provider-provider and patient-provider relationships leading to a supportive work environment and improved PCMC. At the institutional level, it created a system of accountability for providing PCMC and nondiscriminatory care; and collective action and advocacy to address sources of stress.ConclusionCPIPE impacted multiple outcomes in the theory of change leading to improvements in both provider and patient experience, including for the most vulnerable patients. These findings will contribute to global efforts to prevent burnout and promote PCMC and equity.Clinical trial registrationClinicalTrials.gov Identifier:NCT05019131https://www.clinicaltrials.gov/study/NCT05019131?term=Afulani&checkSpell=false&rank=1
A Systematic Review of the Association between Sedentary Behavior and Non-Motor Symptoms of Parkinson’s Disease
Authors: Khan Aiza , Ezeugwa Joy , Ezeugwu Victor 
Published: October 2023

AbstractBackgroundParkinson’s disease, known for motor symptoms, often brings early non-motor issues that severely affect patients’ quality of life. While there are not many effective treatments, physical activity and exercise can help. Yet, another component of the movement intensity continuum warrants examination—prolonged sitting or sedentary behavior. Thus, aim of this study was to perform a systematic review to investigate the relationship between sedentary behaviour and non-motor symptoms, specifically cognitive decline, depression and sleep deficits in Parkinson’s disease.MethodsConforming to PRISMA guidelines, we reviewed the literature up to February 28, 2023, to investigate how sedentary behavior correlates with non-motor symptoms such as cognitive impairment, depression, and sleep disturbances in Parkinson’s disease. A systematic search of the literature was conducted via electronic databases including MEDLINE, CINAHL, Scopus, PubMed and PsycINFO. The eligibility criteria for study selection was: (i) If it studied the Individuals with Parkinson’s disease with sedentary behaviour(iii) studies investigating the association between sedentary behavior and at least one of the non-motor symptoms, including depression, sleep quality, and/or cognitive impairment. New-castle-Ottawa scale for cross-sectional and cohort studies was used to perform quality assessment of the studies.ResultsOf the 463 publications found, 7 studies met the inclusion criteria. All the studies were observational. Total number of cases across all studies were 980. Collectively, these studies show that prolonged sedentary time is associated with increased cognitive, depressive, and sleep-related problems.ConclusionRecognizing sedentary behavior as an independent factor holds pivotal significance. The intricate relationship between sedentary behavior and Parkinson’s disease non-motor symptoms necessitates further exploration to potentially enhance therapeutic strategies for those living with the disease.
Rethinking conceptualizations of adult ADHD and how care is provided: a qualitative study
Authors: Ginapp Callie M. , Greenberg Norman R. , Macdonald-Gagnon Grace , Angarita Gustavo A. , Bold Krysten W. , Potenza Marc N. 
Published: October 2023

AbstractBackgroundAttention-deficit/hyperactivity disorder (ADHD) is a common condition that frequently persists into adulthood. Adults with ADHD often have unmet needs including experiencing high rates of substance use disorders, incarceration, and unemployment. Despite having unmet needs, there is little research on how adults with ADHD conceptualize their condition and how they believe the care they receive could be improved. We aimed to better understand what adults with ADHD would like the medical community to know about what it is like to live with ADHD and to characterize possible misconceptions of ADHD they would like to see addressed.MethodNine online focus groups involving young adults (aged 18-35 years, N = 43) recruited from online communities for people with ADHD were conducted. Data were analyzed using an interpretive phenomenological analysis framework.ResultsIndividually, participants reported wanting increased support, education, and rejection of stigma. Structurally, participants reported desiring ADHD to be reframed as a difference as opposed to a disorder, viewing of ADHD as a mismatch with their environments, and wanting the condition to be viewed through the lens of what it is like to embody the condition.ConclusionsIncorporating patient-lived experiences into psychiatric diagnoses may increase diagnostic patient-centeredness and help healthcare providers better meet patient needs.
Bail-out transvenous temporary pacing during rotational atherectomy PCI
Authors: Schwarz Konstantin , Mascherbauer Julia , Schmidt Elisabeth , Zirkler Martina , Vock Paul , Lamm Gudrun , Kwok Chun Shing , Borovac Josip Andelo , Mousavi Roya Anahita , Hoppe Uta C. , Leibundgut Gregor , Will Maximilian 
Published: October 2023

ABSTRACTBackgroundRotational atherectomy (RA) percutaneous coronary intervention (PCI) may cause transient bradycardia or heart block. Traditionally, some operators use prophylactic transvenous pacing wire (TPW) to avoid haemodynamic complications associated with bradycardia. We sought to establish the frequency of bail-out need for emergency TPW insertion in patients undergoing RA PCI that have received no upfront TPW insertion.MethodsWe performed a single-centre retrospective study of all patients undergoing RA PCI between October 2009 and October 2022. Patient characteristics, procedural variables and in-hospital complications were registered.ResultsA total of 331 patients who underwent RA procedure were analyzed. No patients underwent prophylactic TPW insertion. The mean age was 73.3±9.1 years, 71.6% (n=237) were male, while nearly half of patients were diabetic (N=47.7%, N=158). The right coronary artery was the most common target for RA PCI (40.8%), followed by left anterior descending (34.1%), left circumflex (14.8%) and left main stem artery (10.3%). Twenty (6%) of patients required intraprocedural atropine therapy. Emergency TPW insertion was needed in one patient (0.3%) only. Eight (2.4%) patients died, however only one was adjudicated as possibly related to RA-induced bradycardia. Five patients (1.5%) had ventricular fibrillation arrest while nine (2.7%) required cardiopulmonary resuscitation. Six (1.8%) procedures were complicated by coronary perforation, two (0.6%) were complicated by tamponade while 17 (5.1%) patients experienced vascular access complications.ConclusionsBail-out transvenous temporary pacing is very rarely required during RA PCI. A standby temporary pacing strategy is reasonable and may avoid unnecessary TPW complications compared to routine use.
Knowledge-guided Deep Temporal Clustering for Alzheimer’s Disease Subtypes in Completed Clinical Trials
Authors: Wang Dulin , Ma Xiaotian , Schulz Paul E. , Jiang Xiaoqian , Kim Yejin 
Published: October 2023

AbstractAlzheimer’s disease (AD) is a multifaceted neurodegenerative disorder with varied patient progression. We aim to test the hypothesis that AD patients can be categorized into subgroups based on differences in progression. We leveraged data from three randomized clinical trials (RCTs) to develop a knowledge-guided, deep temporal clustering (KG-DTC) framework for AD subtyping. This model combined autoencoders for contextual information capture, k-means clustering for representation formation, and clinical outcome classification for clinical knowledge integration. The derived representations, encompassing demographics, APOE genotype, cognitive assessments, brain volumes, and biomarkers, were clustered using the Gaussian Mixture Model to identify AD subtypes. Our novel KG-DTC framework was developed using placebo data from 2,087 AD patients across three solanezumab clinical trials (EXPEDITION, EXPEDITION2, and EXPEDITION3), achieving high performance in outcome prediction and clustering. The KG-DTC model demonstrated superior clustering structures, especially when combined with k-means clustering loss. External validation with independent clinical trial data showed consistent clustering results, with a 0.33 silhouette score for three clusters. The model’s stability was confirmed through a leave-one-out approach, with an average adjusted Rand Index around 0.945. Three distinct AD subtypes were identified, each exhibiting unique patterns of cognitive function, neurodegeneration, and amyloid beta levels. Notably, Subtype 3 (S3) showed rapid cognitive decline across multiple clinical measures (e.g., 0.64 in S1 vs. −1.06 in S2 vs. 15.09 in S3 of average ADAS total change score, p<.001). This innovative approach offers promising insights for understanding variability in treatment outcomes and personalizing AD treatment strategies.
DengueSeq: A pan-serotype whole genome amplicon sequencing protocol for dengue virus
Authors: Vogels Chantal B.F. , Hill Verity , Breban Mallery I. , Chaguza Chrispin , Paul Lauren M. , Sodeinde Afeez , Taylor-Salmon Emma , Ott Isabel M. , Petrone Mary E. , Dijk Dennis , Jonges Marcel , Welkers Matthijs R.A. , Locksmith Timothy , Dong Yibo , Tarigopula Namratha , Tekin Omer , Schmedes Sarah , Bunch Sylvia , Cano Natalia , Jaber Rayah , Panzera Charles , Stryker Ian , Vergara Julieta , Zimler Rebecca , Kopp Edgar , Heberlein Lea , Morrison Andrea M. , Michael Scott F. , Grubaugh Nathan D. 
Published: October 2023

AbstractBackgroundThe increasing burden of dengue virus on public health due to more explosive and frequent outbreaks highlights the need for improved surveillance and control. Genomic surveillance of dengue virus not only provides important insights into the emergence and spread of genetically diverse serotypes and genotypes, but it is also critical to monitor the effectiveness of newly implemented control strategies. Here, we present DengueSeq, an amplicon sequencing protocol, which enables whole-genome sequencing of all four dengue virus serotypes.ResultsWe developed primer schemes for the four dengue virus serotypes, which can be combined into a pan-serotype approach. We validated both approaches using genetically diverse virus stocks and clinical specimens that contained a range of virus copies. High genome coverage (>95%) was achieved for all genotypes, except DENV2 (genotype VI) and DENV 4 (genotype IV) sylvatics, with similar performance of the serotype-specific and pan-serotype approaches. The limit of detection to reach 70% coverage was 101-102RNA copies/μL for all four serotypes, which is similar to other commonly used primer schemes. DengueSeq facilitates the sequencing of samples without known serotypes, allows the detection of multiple serotypes in the same sample, and can be used with a variety of library prep kits and sequencing instruments.ConclusionsDengueSeq was systematically evaluated with virus stocks and clinical specimens spanning the genetic diversity within each of the four dengue virus serotypes. The primer schemes can be plugged into existing amplicon sequencing workflows to facilitate the global need for expanded dengue virus genomic surveillance.
Agricultural loan pricing by banks in Ghana: a panel data analysis
Authors: Dziwornu Raymond K. , Yiadom Eric B. , Narteh-yoe Sampson B. 
Published: October 2023

PurposeThe cost of agricultural loans is a major constraint to the growth of the agriculture sector. This paper examines agricultural loan pricing by banks in Ghana using panel data analysis.Design/methodology/approachData were obtained from audited financial reports of 15 agricultural loan lending banks from 2010 to 2017. The study applies the random-effect model and the fixed-effect model in the analysis and uses the system generalized system method of moment to check the robustness of the results from the baseline models.FindingsThe study found that agricultural loan pricing by banks is significantly influenced by risk premium, cost of funds, loan impairment, agricultural growth rate and food inflation. Banks should leverage emerging technologies to de-risk agriculture loan pricing to allay the fear of default. Farmers should look for long-term and relatively cheaper funds to support agricultural loans. Increasing credit to the agricultural sector could increase output, thereby reducing food inflation uncertainty for competitive pricing of agricultural loans.Originality/valueAgriculture employs about 52% of Ghana's labor force, contributing about 20% to GDP. But it is “under” financed. This study leads the way in unraveling the factors accounting for the high prices of agricultural loans in Ghana. This study further contributes to policy development toward increasing credit to the agricultural sector.
Ayahuasca ceremonies: set and setting features across Italy and Colombia
Authors: Ambrosini Federica , Pariset Laura , Biolcati Roberta 
Published: October 2023

PurposeAyahuasca ceremonies are currently practiced all over the world. This study aims to investigate ayahuasca ceremonies in Colombia (where ayahuasca use is culturally entrenched) and Italy (where ayahuasca use has only recently spread).Design/methodology/approachIn total, 32 Italian (53% males; 47% females) and 28 Colombian (79% males; 21% females) ayahuasca ceremony participants completed an online survey. Ceremonial setting and set (motivations for ayahuasca use, ayahuasca perceived effects and features of participants, i.e. drug use and problematic use, interpersonal dependency, spiritual orientation and quality of life) were investigated. Mann–Whitney U test, Pearson’sχ2test and Fisher’s exact test were used to compare the Italian and Colombian samples.FindingsNo differences emerged in the ceremonial setting. Slight differences were observed in motivations for ayahuasca intake and religious beliefs, but not in the preparation for ceremonies, quality of life, interpersonal dependence and spiritual orientation. Italians showed greater use of other psychoactive substances and more drug use problems.Practical implicationsPrevention regarding safer practices of consumption should be promoted to avoid improper uses.Originality/valueFew studies have explored ayahuasca ceremonies (set and setting characteristics) in countries with different traditions on ayahuasca consumption. The results highlight that the use and experience of ayahuasca can take on different meanings depending on the cultural context.
The customer perception of project value scale: development and validation
Authors: Cândido Da Silva Eduardo André , Bizarrias Flávio Santino , Penha Renato , Silva Luciano Ferreira da , Pedron Cristiane Drebes 
Published: October 2023

Purpose
Despite the significant interest from researchers and practitioners, the literature on project value measurement from the perspective of the customer is non-existent. This study aims to address this gap by developing and validating a scale to measure project value through a customer lens called the customer perception of project value scale.

Design/methodology/approach
A list of items was initially generated based on 762 sample responses through a systematic review of the literature and with the participation of specialists. Exploratory and confirmatory factorial analyses and structural equation modelling were used to develop and validate the scale.

Findings
The authors formulated a four-dimension scale. The dimensions used to measure the second-order construct are customer centrality, process, delivery and cost-benefit. This was validated using a nomological structure.

Research limitations/implications
The non-consensual nature of what is value in projects restricts the results of this study to the context of a specific group of stakeholders only, that is, the consumers of the projects. The authors also see limitations in the absence of competing scales, which do not allow the comparison of the instrument with alternative measures.

Practical implications
This study allows project managers and other professionals to measure a project’s perceived value from the customer’s point of view and manage the improvement of this perception.

Originality/value
To the best of the authors’ knowledge, this is the first study to propose a scale to measure project value, which advances the literature on project management and value and contributes to academic knowledge and practice by measuring project value from the customer standpoint.
Extrinsic rewards for employee creativity? The role of perceived organisational support, work engagement and intrinsic motivation
Authors: Aldabbas Hazem , Pinnington Ashly , Lahrech Abdelmounaim , Blaique Lama 
Published: October 2023

Purpose
This study aims to investigate the relationship between extrinsic rewards and employee creativity through the intervening mechanism of perceived organisational support (POS) and work engagement. The moderating role of intrinsic motivation on the relationship between work engagement and employee creativity is also examined.

Design/methodology/approach
The authors report the results of a survey completed by 372 respondents employed in the United Arab Emirates. Structural equation modelling was applied to test the hypothesised relationships.

Findings
The main findings are that extrinsic rewards influence employee creativity through POS and work engagement. Moreover, the effect of work engagement on employee creativity is moderated by intrinsic motivation. This model effect is stronger for employees with high intrinsic motivation.

Research limitations/implications
Convenience sampling was used, which limits its generalisability. Also, the data were collected through a cross-sectional survey at one point in time.

Practical implications
Managers should consider provision of extrinsic rewards and support to increase employee motivation and engagement in creative work.

Originality/value
This study contributes to the limited amount of available literature on creativity and rewards adding to our knowledge about the influence of extrinsic rewards on creativity considered in the presence of intrinsic motivation. Theoretical and practical recommendations are discussed.
Co-production of social innovations and enabling ecosystems for social enterprises
Authors: Perikangas Sofi , Kostilainen Harri , Kainulainen Sakari 
Published: October 2023

PurposeThe purpose of this article is to show (1) how social innovations are created through co-production in social enterprises in Finland and (2) how enabling ecosystems for the creation of social innovations can be enhanced by the government.Design/methodology/approachThis study is a descriptive case study. The data comprises focus group interviews that were conducted during a research project in Finland in 2022. The interviewees represented different social enterprises, other non-profit organisations and national funding institutions.FindingsSocial enterprises create social innovations in Finland through co-production, where service innovation processes, activism and networking are central. Also, to build an enabling ecosystem, government must base the system upon certain elements: enabling characteristics of the stakeholders, co-production methods and tools and initiatives by the government.Originality/valueThe authors address an important challenge that social enterprises struggle with: The position of social enterprises in Finland is weak and entrepreneurs experience prejudice from both the direction of “traditional” businesses and the government which often does not recognise social enterprise as a potential partner for public service delivery. Nonetheless, social enterprises create public value by contributing to the co-production of public services. They work in interorganisational networks by nature and can succeed where the traditional public organisations and private businesses fail.
Hydroforming of double-layer Y-shaped tube controlled by a novel backward punch shape
Authors: Feng Ying Ying , Jia Yue , Sun Xiao Qian , Chen Guo Peng , Luo Zong An 
Published: October 2023

PurposeA new backward punch shape was designed and used in the hydroforming process of double-layer Y-shaped tubes to achieve uniform wall thickness. This study focuses on the implementation and effectiveness of this novel punch shape.Design/methodology/approachA numerical simulation and experimental validation of the hydroforming process of double-layer Y-shaped tubes under various backward punch, replenishment ratios (left and right feed ratios) and internal pressure loading paths was performed using finite elements. During the hydroforming process, an analysis was made on the distribution of stress, strain and wall thickness in both the inner and outer layers of the Y-shaped conduit.FindingsThe novel backward punch parallel to the main tube has been found to improve the distribution of wall thickness in Y-shaped tubes. By controlling the feeding ratio and modifying the loading path of the internal pressure, it is possible to obtain the optimal forming part of the double-layer Y-shaped tube. The comparison between the simulation and experimental results of the double-layer Y-shaped tube formed under the optimal path indicates that the error is within 5% and the distribution of wall thickness is consistent.Originality/valueA novel backward punch technique is employed to control the hydroforming process in a Y-shaped tube. A study on hydroforming of double-layer Y-shaped tubes with asymmetric features and challenging forming conditions is being suggested.