bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating Place and Sense of Place into Geovisualizations of Hurricane Storm Surge Risk
Authors: Wilhelmi O. V. , Chamberlain B. C. , Morss R. E. , Demuth J. L. , Walpole H. D. , Boehnert J. , Gambill J. M. , Lazrus H. , Dobson J. G. 
Published: October 2023

Abstract
Geovisualizations play a central role in communicating hurricane storm surge risks to the public by connecting information about the hazard to a place. Meanwhile, people connect to places through meaning, functions, and emotional bond, known as a sense of place. The mixed-method approach presented in this paper focuses on the intersection of sense of place, geovisualization, and risk communication. We explored place meaning, scale of place, and place attachment in the coastal communities in Georgia and South Carolina. We conducted cognitive mapping focus groups and developed a series of geovisualizations of storm surge risk with varying representations of place. We then investigated people’s ability to connect visual storm surge information to a place and understand their risk by testing these geovisualizations in a large population survey (n = 1442). We found that a 2D regional-scale map displayed together with a 3D abstract representation of a neighborhood was the most helpful in enabling people to relate to a place, quickly make sense of the information, and understand the risk. Our results showed that while the geovisualizations of storm surge risk can be effective generally, they were less effective in several important and vulnerable groups. We found substantial impacts of race, income, map-reading ability, place attachment, and scale of place on how people connected the storm surge risk shown in the visual to a place. These findings have implications for future research and for considering the way weather forecasters and emergency managers communicate storm surge information with diverse audiences using geovisualizations.

Significance Statement
Weather forecasters and emergency managers often use geovisualizations to communicate hurricane storm surge risks and threats to the public. Despite the important role that geovisualizations play, few studies have empirically investigated their effectiveness in hazardous weather risk communication. With the overarching goal of understanding how geovisualizations enable coastal residents to understand and respond to risk, we use an interdisciplinary approach to create new knowledge about the effectiveness of geovisualizations in storm surge risk communication. Our results show substantial impacts of sociodemographic factors across many of the measures that enable people to connect to a place through visualizations. These findings have implications for communicating geospatially varying risk to diverse audiences.
Twenty-Five Year Multicentre Experience of Explantation of Infected Abdominal Aortic Endografts
Authors: Perini Paolo , Gargiulo Mauro , Silingardi Roberto , Bonardelli Stefano , Bellosta Raffaello , Piffaretti Gabriele , Michelagnoli Stefano , Ferrari Mauro , Turicchia Giorgio Ubaldo , Freyrie Antonio ,   On Behalf of the LOCOS-1 Investigators (Late Open COnversions and Semiconversions-1 Investigators), Fornasari Anna , Mariani Erica , Faggioli GianLuca , Spath Paolo , Migliari Mattia , Gennai Stefano , Paro Barbara , Baggi Paolo , Attisani Luca , Pegorer Matteo , Franchin Marco , Mauri Francesca , Chisci Emiliano , Troisi Nicola , Paciaroni Elisa , Fanelli Mara 
Published: October 2023

We report a multicenter experience of open conversions (OC) for aortic endograft infections (AEI). We retrospectively analyzed all patients who underwent OC for AEI after endovascular aneurysm repair (EVAR), from 1997 to 2021 in 12 Italian centers. The endpoints were as follows: mortality (30-days, in-hospital), major postoperative complications. Follow-up data included: survival, aortic-related complications, infection persistence or reoccurrence. Fifty-eight patients (mean age: 73.8 ± 6.6 years) were included. Median time from EVAR to OC was 14 months (interquartile range 7–45). Thirty-five patients (60.3%) were symptomatic at presentation. Aortic reconstruction was anatomic in 32 patients (55.2%), extra-anatomic in 26 (44.8%). Thirty-day mortality was 31% (18/58). Six additional patients died after 30 days during the same hospitalization (in-hospital mortality: 41.4%). Most common post-operative complications included respiratory failure (38.6%) and renal insufficiency (35.1%). During 28.1 ± 4 months follow-up, 4 aneurysm-related deaths were recorded. Infection re-occurred in 29.4% of the patients. Estimated survival was 50% at 1 year, and 30% at 5 years, and was significantly lower for patients who underwent extra-anatomic reconstructions (37 vs 61% at 1 year, 16 vs 45% at 5 years; log-rank P = .021). OC for AEI is associated with high early mortality. The poor mid-term survival is influenced by aortic complications and infection re-occurrence.
Intra-articular autologous conditioned serum and triamcinolone injections in patients with knee osteoarthritis: a controlled, randomized, double-blind study
Authors: Damjanov Nemanja , Zekovic Ana 
Published: October 2023

Objective This study was performed to assess the impact of autologous conditioned serum (ACS) when added to preceding intra-articular glucocorticoid therapy on pain, function, and quality of life outcomes over 24 weeks. Methods In this single-center, randomized controlled trial involving 40 patients with advanced knee osteoarthritis (Kellgren–Lawrence grades III and IV), ACS or saline placebo was injected after 40 mg triamcinolone acetonide (TA) intra-articular injection. Numerical rating scale (NRS) pain scores and Knee Injury and Osteoarthritis Outcome Score (KOOS) assessments were conducted at baseline and at weeks 3, 6, 12, and 24. The primary endpoint was the change in KOOS Pain at 24 weeks. Patient safety events were also monitored. Results At week 24, TA + ACS significantly improved KOOS Pain, Symptoms, Activities of Daily Living, Quality of Life, and KOOS Sport scores. TA + ACS also outperformed TA + placebo in NRS pain scores (average and maximum intensity) at week 24 and NRS pain score (at rest) at weeks 12 and 24. The TA injection followed by ACS or placebo was well-tolerated. Conclusion ACS adds long-term pain relief and functional improvement to the short-term pain relief provided by glucocorticoids.
Youtube is an unreliable source of information about delayed ejaculation treatment
Authors: Demirci Aykut , Başar Halil 
Published: October 2023

Background: Social platforms such as YouTube have become sources of information about diseases as they can be easily and rapidly accessed. However, this also has the risk of ill-intentioned content and misleading information. Objective: To evaluate the reliability of YouTube video content about delayed ejaculation treatment. Material and methods: YouTube videos were searched using the terms “delayed ejaculation,” “retarded ejaculation,” “inhibited ejaculation,” and “anejaculation.” Videos were excluded if they were not in English, were not related to the subject, or did not have audio and visual content. In accordance with the scientifically proven accurate information, the videos were separated as reliable (Group 2, n: 112) and unreliable videos (Group 1, n: 94). The groups were compared in respect of the video characteristics, and the scores obtained in the DISCERN-5, Global Quality Scale, the Patient Education Materials Assessment Tool Audiovisual, and the Journal of the American Medical Association scales. Intraclass correlation test was used to evaluate the level of agreement between the two investigators. Results: Of the 1200 videos, 994 were excluded. No significant difference was determined between the Group 1 and Group 2 in respect of the median number of views [1672 (4555) vs 1547 (28,559), p = 0.63] and likes [10 (42) vs 17 (255), p = 0.07]. There was a greater number of videos in the Group 2 (54.4%) and the points obtained on the scoring scales were significantly higher than the Group 1 ( p < 0.001). The videos originating from universities/professional organizations/non-profit physician/physician group were comprised the majority of the reliable videos (55.3%) and the unreliable videos had more content related to treatment (71.4%) ( p < 0.001). Conclusion: Although there was a greater number of reliable videos related to the problem of delayed ejaculation, the content could be misleading and should be avoided by patients seeking treatment without consulting a physician.
Skeletal Growth Arrest Lines in Fetal Remains: Histopathology and Correlative Placental Pathology
Authors: Chu Tsz Wing , Shannon Patrick , Parks Tony 
Published: October 2023

Introduction: Skeletal growth arrest lines (GAL) are transverse lines of metaphyseal radiodensity accompanying episodic severe physiological stress. They are poorly described in fetal remains. Materials and Methods: We searched our autopsy practice for instances of fetal GAL in post mortem radiology, and correlated them with long bone histology and placental pathology. We describe the appearance, distribution, and pathology of GAL in a cohort of fetal autopsies, and compare the placental pathology accompanying GAL to the placental pathology of asymmetrical growth restriction (AGR) in the same time period. Results: In 2108 consecutive fetal post mortems, we found 20 cases with GAL. About 16 were in singletons with AGR. In these 16, the distribution of placental pathologies was similar to a contemporaneous cohort of 113 cases with AGR. Of the remaining 4, two twins out of 9 sets of monochorionic twins with AGR demonstrated GAL. One case of GAL had symmetrical growth restriction with cytomegalovirus infection, and one case had no AGR and an old, unexplained retroplacental hemorrhage. On histology, GAL are characterized by a region of mineralized chondroid, which is variably incorporated into irregular trabecular bone. Discussion: GALs accompany a variety of placental pathologies and twin-twin transfusion, suggesting episodic disease progression.
Low-intensity resistance exercise with blood flow restriction for patients with claudication: A randomized controlled feasibility trial
Authors: Parkington Thomas , Broom David , Maden-Wilkinson Thomas , Nawaz Shah , Klonizakis Markos 
Published: October 2023

Background: Claudication is a common and debilitating symptom of peripheral artery disease, resulting in poor exercise performance and quality of life (QoL). Supervised exercise programs are an effective rehabilitation for patients with claudication, but they are poorly adhered to, in part due to the high pain and effort associated with walking, aerobic, and resistance exercise. Low-intensity resistance exercise with blood flow restriction (BFR) represents an alternative exercise method for individuals who are intolerant to high-intensity protocols. The aim of this study was to evaluate the feasibility of a supervised BFR program in patients with claudication. Methods: Thirty patients with stable claudication completed an 8-week supervised exercise program and were randomized to either BFR ( n = 15) or a control of matched exercise without BFR (control; n = 15). Feasibility, safety, and efficacy were assessed. Results: All success criteria of the feasibility trial were met. Exercise adherence was high (BFR = 78.3%, control = 83.8%), loss to follow up was 10%, and there were no adverse events. Clinical improvement in walking was achieved in 86% of patients in the BFR group but in only 46% of patients in the control group. Time to claudication pain during walking increased by 35% for BFR but was unchanged for the control. QoL for the BFR group showed improved mobility, ability to do usual activities, pain, depression, and overall health at follow up. Conclusion: A supervised blood flow restriction program is feasible in patients with claudication and has the potential to increase exercise performance, reduce pain, and improve QoL. (Clinicaltrials.gov Identifier: NCT04890275)
Analytical assessment of the full-bridge response to the vertical live load: An algorithm for hybrid cable-stayed suspension bridges
Authors: Zhang Wen-ming , Chen Jie , Chang Jia-qi , Tian Gen-min , Liu Tian-cheng 
Published: October 2023

Hybrid cable-stayed suspension bridges combine the advantages of cable-stayed and suspension bridges, mitigating their deficiencies. Due to its super spanning ability, this novel form of bridge enjoys a bright application prospect as a large-span structure. This study introduces an analytical algorithm to estimate the full-bridge response of a hybrid cable-stayed suspension bridge with a vertical uniformly distributed load applied to the main beam. This method is based on the assumption that all parameters, such as the geometric configuration, internal force distribution, and material properties, of the whole bridge under a dead load are known; then, it analyzes the full-bridge response under a live load. First, the minimum and independent basic unknown parameters of the full-bridge response are determined. Next, the governing equations are derived and solved based on the conservation of unstressed length of each section of cable, closure of span lengths and elevation difference in different spans, and conditions for stress balance of the main beam. Thus, the values of basic unknown parameters are obtained. Finally, they are substituted into the governing equations to estimate the full-bridge response, including each bridge component’s internal forces and deflections. The proposed analytical method involves no iterative procedures when dealing with nonlinear problems but only focuses on the bridge’s state with and without loading. The results are obtained directly by solving the equations, which have the advantages of high efficiency, simplicity, and clear physical meaning. Finally, the feasibility and effectiveness of the proposed method are verified by a finite-element-based calculation of an exemplary asymmetric cable-stayed suspension cooperation system bridge with a main span of 1400 m.
Use of angled-tip aspiration catheters is associated with a lower cost of thrombectomy in patients with acute ischemic stroke secondary to large and medium vessel occlusions
Authors: Ezzeldin Mohamad , Ota Riichi , Riha Eric , Delora Adam , Alenzi Bader , Gordon Victoria , Gupta Himanshu , Ezzeldin Rime , Bushnaq Saif 
Published: October 2023

Background Recently, the angled-tip Zoom™ aspiration catheters were introduced. The tip is designed to improve suction force for clot retrieval. We evaluated the possibility of reducing procedure costs when using angled-tip catheters and compared the safety and angiographic effectiveness of angled-tip versus straight-tip catheters. Methods We conducted a retrospective single-center cohort study involving patients with acute ischemic stroke due to large and medium vessel occlusions. The patients were divided into two groups: the post-Zoom group, in which angled-tip aspiration catheters were used and the pre-Zoom group, in which traditional straight-tip catheters were employed. Results A total of 163 patients were included; 95 (58.3%) in the pre-Zoom group and 68 (41.7%) in the post-Zoom group. The groups were well-matched at entry. The post-Zoom group demonstrated a significant decrease in mean procedure cost ($9728 vs. $12,127; p = 0.002), shorter time to achieve modified thrombolysis in cerebral infarction ≥2b reperfusion (38.30 min vs. 53.26 min; p = 0.018), and shorter puncture to procedure completion time (46.42 min vs. 62.38 min; p = 0.022). Additionally, the mean procedural cost when using the ADAPT technique supported by the Zoom catheters was significantly lower than the Solumbra technique ($5754 ± $2806 vs. $13,498 ± $3244, p < 0.001). There were no differences in the rate of hemorrhage between the pre-Zoom group (17.9%) and the post-Zoom group (20.6%), p = 0.690. Conclusion The study demonstrated significant benefits, including cost reduction and shorter time to achieve reperfusion in patients treated with Zoom aspiration catheters. These findings support the use of angled-tip catheters in acute ischemic stroke management.
Evaluation of functional, perioperative outcomes and common complications of robot-assisted vs open construction of orthotopic neobladder following a radical cystectomy in patients with bladder cancer: A systematic review
Authors: Bhiryani Mansha , El-Taji Omar , Hanchanale Vishwanath 
Published: October 2023

Introduction: Orthotopic neobladder (ONB) reconstruction following radical cystectomy for bladder cancer is a viable alternative to the formation of an ileal conduit. Although robotic surgery is gaining popularity, neobladder reconstruction is still most commonly done extra-corporeally (eONB) with a lower midline-laparotomy rather than intra-corporeal ONB (iONB) reconstruction. The novelty of a robotic approach has made several centres apprehensive to adopt this. This systematic review aims to compare functional outcomes as well as perioperative outcomes and common complications of robotic-assisted radical cystectomy with iONB versus eONB reconstruction. Materials and methods: A search of the literature from 2011 to 2021 was performed through PubMed, EMBASE, Medline and Scopus to identify articles comparing eONB formation with iONB formation. Urodynamic (UDS) outcomes (bladder volume, flow rate, post-voiding residual volume, continence rates and rate of clean intermittent catheterization (CIC) use) and perioperative outcomes (estimated blood loss, length of stay and operative time) were extracted as endpoints of interest. This review was registered with PROSPERO on 19 October 2022 (CRD42022366667). Results: Our searches identified 84 abstracts, of which 4 articles with 410 patients were eligible. Our results showed patients undergoing iONB had a higher bladder capacity and continence rate and achieved full continence much sooner than eONBs. iONBs, however, seemed to be left with higher residual volumes and a higher percentage of patients who needed CIC to void. Conclusion: Both perioperative outcomes and complications favoured the iONB technique; however, eONB seemed to give better functional outcomes. Level of evidence: Not applicable
Assessing the Prevalence, Predictors, and Consequences of Secondary Traumatic Stress Among Emergency Nurses in Palestine During the COVID-19 Pandemic
Authors: Salameh Basma , Daibes Abdalla Ghassen , Qaddumi Jamal 
Published: October 2023

Introduction Emergency nurses who are working in direct contact with COVID-19 patients are at an increased risk of developing secondary traumatic stress disorder. This study aimed to assess the prevalence, predictors, and consequences of secondary traumatic stress among emergency nurses in Palestine during the COVID-19 pandemic Methods The study utilized a cross-sectional design and recruited a total of 189 emergency nurses from multiple healthcare centers in Palestine. Data collected from January 21, 2021, to March 31, 2021. Results The study revealed that emergency nurses had a high degree of secondary traumatic stress with the prevalence of high to severe symptoms of secondary traumatic stress being 61% of the total participants. In terms of predictors, the results showed that years of experience, level of education, burnout, and organizational support were significantly correlated with secondary traumatic stress and thus that years of experience and burnout are predictors of secondary traumatic stress. Conclusion Based on our findings, nurses in emergency departments in Palestine have a high degree of secondary traumatic stress disorder which impacts their lives on a personal and professional level.
Tissue-specific transcriptome and metabolome analyses reveal candidate genes for lignan biosynthesis in the medicinal plant Schisandra sphenanthera
Authors: Sun Boshi , Wang Peng , Guan Meng , Jia Entong , Li Qian , Li Jun , Zhou Ziyun , Ma Pengda 
Published: October 2023

AbstractSchisandra sphenanthera is an extremely important medicinal plant, and its main medicinal component is bioactive lignans. The S. sphenanthera fruit is preferred by the majority of consumers, and the root, stem, and leaf are not fully used. To better understand the lignan metabolic pathway, transcriptome and metabolome analyses were performed on the four major tissues of S. sphenanthera. A total of 167,972,229 transcripts and 91,215,760 unigenes with an average length of 752 bp were identified. Tissue-specific gene analysis revealed that the root had the highest abundance of unique unigenes (9703), and the leaves had the lowest (189). Transcription factor analysis showed that MYB-, bHLH- and ERF-transcription factors, which played important roles in the regulation of secondary metabolism, showed rich expression patterns and may be involved in the regulation of processes involved in lignan metabolism. In different tissues, lignans were preferentially enriched in fruit and roots by gene expression profiles related to lignan metabolism and relative lignan compound content. Furthermore, schisandrin B is an important compound in S. sphenanthera. According to weighted gene co-expression network analysis, PAL1, C4H-2, CAD1, CYB8, OMT27, OMT57, MYB18, bHLH3, and bHLH5 can be related to the accumulation of lignans in S. sphenanthera fruit, CCR5, SDH4, CYP8, CYP20, and ERF7 can be related to the accumulation of lignans in S. sphenanthera roots. In this study, transcriptome sequencing and targeted metabolic analysis of lignans will lay a foundation for the further study of their biosynthetic genes.
A new Plasmodium vivax reference genome for South American isolates
Authors: De Meulenaere Katlijn , Cuypers Bart , Gamboa Dionicia , Laukens Kris , Rosanas-Urgell Anna 
Published: October 2023

AbstractBackgroundPlasmodium vivaxis the second most important cause of human malaria worldwide, and accounts for the majority of malaria cases in South America. A high-quality reference genome exists for Papua Indonesia (PvP01) and Thailand (PvW1), but is lacking for South America. A reference genome specifically for South America would be beneficial though, asP. vivaxis a genetically diverse parasite with geographical clustering.ResultsThis study presents a new high-quality assembly of a South AmericanP. vivaxisolate, referred to as PvPAM (P. vivaxPeruvian AMazon). The genome was obtained from a low input patient sample from the Peruvian Amazon and sequenced using PacBio technology, resulting in a highly complete assembly with 6497 functional genes. Telomeric ends were present in 17 out of 28 chromosomal ends, and additional (sub)telomeric regions are present in 12 unassigned contigs. A comparison of multigene families between PvPAM and the PvP01 genome revealed remarkable variation invirgenes, and the presence of merozoite surface proteins (MSP) 3.6 and 3.7. Threedhfranddhpsdrug resistance associated mutations are present in PvPAM, similar to those found in other Peruvian isolates. Mapping of publicly available South American whole genome sequencing (WGS) data to PvPAM resulted in significantly fewer variants and truncated reads compared to the use of PvP01 or PvW1 as reference genomes. To minimize the number of core genome variants in non-South American samples, PvW1 is most suited for Southeast Asian isolates, both PvPAM and PvW1 are suited for South Asian isolates, and PvPAM is recommended for African isolates. Interestingly, non-South American samples still contained the least subtelomeric variants when mapped to PvPAM, indicating high quality of the PvPAM subtelomeric regions.ConclusionsOur findings show that the PvPAM reference genome more accurately represents South AmericanP. vivaxisolates in comparison to PvP01 and PvW1. In addition, PvPAM has a high level of completeness, and contains a similar number of annotated genes as PvP01 or PvW1. The PvPAM genome therefore will be a valuable resource to improve future genomic analyses onP. vivaxisolates from the South American continent.