bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of medium-high shelf life ready-to-use dough rolls for making “pizza napoletana”
Authors: Falciano Aniello , Di Pierro Prospero , Sorrentino Angela , Cavella Silvana , Masi Paolo , Romano Annalisa 
Published: December 2023

The aim of this work was to investigate the possibility of developing an innovative technology to obtain ready-to-use dough rolls with a medium-high shelf life, useful for pizza-making within the disciplinary procedures of Pizza Napoletana production. For this purpose, dough obtained according to the classic recipe was leavened for 20 min at 25°C, divided into 250 g dough rolls, and further leavened for 8 (C8) or 16 h (C16) at 22°C before packaging. The packed samples were stored at 2.0 ± 0.5°C for 28 days. Every 7 days, colony-forming units, pH, total titratable acidity, volume, and the consistency of the dough rolls were evaluated. After 28 days, the samples with the longer leavening time (C16) exhibited similar characteristics to the fresh product. In addition, the ability of the dough to develop a pizza rim was evaluated through cooking tests after 28 days of storage: the rims of the C16 rolls were similar to that of the fresh product. These results represent an important starting point for large-scale marketing of ready-to-use dough rolls, allowing consumers to taste a real “Pizza Napoletana” (TSG) product even in pizzerias outside the Campania region.
Fracture analysis in 2D plane strain problems for composite materials containing hard inclusions and voids using an extended consecutive-interpolation quadrilateral element
Authors: Hoang Binh Hai , Lo Vay Siu , Tran Bang Kim , TRUONG Thien Tich 
Published: December 2023

This paper investigates fracture mechanics in particle-reinforced composites by using the extended finite element method enhanced by the consecutive-interpolation quadrilateral element. These composite materials have discontinuous boundaries such as cracks, voids, holes, and soft inclusions. And the extended consecutive-interpolation quadrilateral element (XCQ4) is employed to model these boundaries in two-dimensional linear elastic deformation problems. XCQ4 combines the enrichment functions in the traditional extended finite element method with the consecutive interpolation on a 4-node quadrilateral element. This element uses both nodal values and averaged nodal gradients as interpolated conditions. In fracture analysis, the stress intensity factors (SIFs) are important parameters that must be defined. In this study, the values of SIFs at the crack tips are evaluated with the help of the interaction integrals approach. The obtained numerical results are compared with other reliable results showing high accuracy and convergence rate of the XCQ4 element.
New method for determining the mode I fracture toughness of shotcrete: edge-notched partial disc test
Authors: Manesh Mohammad Omidi , Sarfarazi Vahab , Babanouri Nima , Rezaei Amir , Far Arsham Moayedi 
Published: December 2023

The fracture toughness (mode I) of shotcrete specimens was obtained using edge-notched partial disc (ENPD) specimens. Notched Brazilian discs (NBDs) were also tested to validate the results of the ENPD experiments. Numerical analysis was also conducted on the ENPD results to compare the measured and numerically obtained fracture toughness values. The notch lengths in the ENPD specimens were 15, 30, 45 and 60 mm, while the notch lengths in the NBD specimens were 10, 20, 30, 40, 50 and 60 mm. It was found that the flat joint model accurately predicted the potential crack growth path and crack initiation stress as compared with the experimental results. It was also deduced that the fracture toughness was roughly the same with an increase in the notch length. The tensile strength (σt) and fracture toughness (KIC) of the shotcrete specimens were found to be meaningfully correlated (σt = 7.92KIC). The ENPD tests yielded the lowest fracture toughness values because of the pure tensile stress distribution on the failure surface. It was also found that the derived fracture extension patterns from the laboratory investigations were in acceptable agreement with the outputs of numerical simulations.
Important issues of professional burnout among hematologists and hematology department nursing staff during the COVID-19 pandemic
Authors: Aleshina O. A. , Nikitina T. P. , Porfirieva N. M. , Vybornykh D. E. , Parovichnikova E. N. , Ionova T. I. 
Published: December 2023

Background. Professional burnout (PB) among medical staff, namely hematologists, is of major importance, especially given the current shortage of personnel. It is of extreme value during the COVID-19 pandemic.Aim. To determine the degree of PB development among hematologists and nursing staff of hematological departments of federal and regional medical institutions in the context of the COVID-19 pandemic and to identify the associated factors.Materials and methods. The study was conducted in the period from July 2022 to September 2022 in the form of a onetime online survey of hematologists and nursing staff of hematology departments of federal and regional medical institutions in different cities of the Russian Federation. To interview specialists, a special checklist based on an Internet resource (Google forms) was used. It included burnout questionnaire Maslach Burnout Inventory (MBI) and questions related to factors that may be associated with the formation of PB. Statistical analysis included pairwise and multiple comparisons, as well as χ2 test, correlation and logistic regression analysis.Results. A total of 162 specialists took part in the online survey. More than half of the specialists (52 %) had high degree of emotional exhaustion, high level of depersonalization was detected in 39.5 % of specialists, and low level of personal accomplishment – in one third of specialists (32.1 %). It was shown that physicians, compared with nurses, had significantly higher indicators of PB. The level of problems for all PB components was significantly lower among specialists working in federal health facilities than among specialists working in regional clinics. The specialists who worked in the “red zone” showed a greater degree of emotional exhaustion and depersonalization than the specialists who did not work in the “red zone” during the pandemic. The formed PB syndrome was observed in 16 % of specialists, and its signs – in 42 %. The risk of PB was significantly greater in hematologists than in nurses, as well as among specialists with increased levels of depression and anxiety and dissatisfaction with the level of personal protective measures.Conclusion. The high importance of PB and the need for preventive measures among specialists of hematological centers and hematology departments in the Russian Federation is shown.
STATE OF THYROID GLAND FUNCTION IN PATIENTS ADMITTED TO CORONARY CARE UNIT
Authors: Khaznadar Amanj , Baban Zaynab 
Published: December 2023

Background
A large number of patients are admitted to coronary care units daily. Thyroid gland abnormalities are one of the reasons which cause people to have cardiac events. Therefore, detecting thyroid gland abnormalities among cardiac care unit patients and early management leads to less morbidity/mortality and a better long-term prognosis for those patients.
Objectives
The study was done to detect the function of thyroid gland abnormalities and their effect on different cardiac conditions among patients admitted to CCU.
Patients Methods
This descriptive cross-sectional study includes a consecutive non-random sampling of 201 patients. All the patients enrolled in this study were admitted to the CCU unit of Sulaimanya Teaching Hospital and Shar Hospital in Sulaimanya city/Iraq between August 2021 and January 2022. Thyroid function test and lipid profile were checked for the participants. The pediatric age group, pregnant women, patients with malignancies/ severe systemic illness /on amiodarone/ congenital heart disease were excluded. Statistical Package analysed the collected data for Social Science (SPSS) (version 22.0).
Results
One hundred fifteen (57.2%) participants were male, and 86(42.8%) were female. The most common age group was between 45-64 years. HTN(%44.3), diabetes (29.9%) and hyperlipidemia (17.9%) were common comorbid conditions. The most common cause of admissions to CCU was due to ACS (63.2%) and then arrhythmia (22.9%), decompensated heart failure (12.9%) and pericardial diseases (1%). In addition, 82.59% (166) of the participants were euthyroid, and 17.41% (35) had thyroid gland function abnormalities.
Conclusion
The effect of thyroid hormone problems on cardiac conditions is one of the important causes of CCU admissions. Patients with ACS and heart failure are presented with hypothyroidism. However, arrhythmia is present more in cases of hyperthyroidism.
Restoration of Global Offset and Limb Length in Primary Unilateral Total Hip Arthroplasty When Preoperative Templating is not Applied
Authors: Kamal Miran , Saeed Arewan , Mahmud Kawa 
Published: December 2023

Background: Preoperative templating is an essential step before performing any total hip arthroplasty (THA). Restoration of global offset (GO) and limb length (LL) were among the templating purposes. Thus, we aimed to perform THA without preoperative templating based on clinical examination and intra-operative anatomical landmarks to restore hip biomechanics.Patients and Methods: This prospective observational study was conducted on 40 patients with primary THA through the posterior approach. The lesser trochanter was used to determine the level of femoral neck cut, the femoral component insertion depth, and version, along with adjusting the level of the center of the femoral head to the tip of the greater trochanter. The transverse acetabular ligament (TAL) was used as a reference for the acetabular component version and inclination. To optimize the LL, preoperative clinical assessment, intra-operative comparison with the normal side, soft tissue tension, and shuck test were used. GO was adjusted using the depth of acetabulum after reaming, placing the acetabular component fit or 10% overhang from the ridge and gluteus medius muscle tension. Postoperatively, computed tomography (CT) scan was used for measuring the GO (acetabular offset (AO) + femoral offset (FO)) and limb length discrepancy (LLD) and compared to the sound side. Pre and postoperatively, LL was measured using a tape measure from the anterior superior iliac spine (ASIS) to the medial malleolus.Results: Depending on postoperative CT measurements, there was no significant difference between the mean normal and operative GO (P=0.894). The mean LL difference between the two sides was 0.38 cm (P=0.007). Clinically, the mean LLD (comparing the normal side with the operated side preoperatively) was 1.001 cm, while the mean LLD was 0.722 cm (P=0.0455).Conclusions: This study demonstrated that when the preoperative templating step is omitted, depending on intraoperative landmarks, neither the GO nor the AO and FO of the operated side were significantly affected. The mean radiological and clinical postoperative LLD was almost consistent, and the mean difference was < 1 cm, which is within the acceptable range. Do not use abbreviations in abstract and conclusions.
Taxonomic Studies on Family Euphorbiaceae Based on Some Morphological, Biochemical and Molecular Characteristics
Authors: Ashwaq T. Althobaiti  
Published: December 2023

An informal group of scientists from multiple nations formed the Angiosperm Phylogeny Group (APG), in which experts work together for the development of taxonomy of angiosperms. The group took into account all new information about diverse plant species using a high steering phylogenetic investigation. The APG has developed four classification systems from 1998 through 2003 and 2009 up until 2016. Since, the previously classified angiosperm species and their wild relatives were not fully based on monophyletic grouping, the classification has a lot of shortcoming and faults. According to the Angiosperm Phylogeny Group system, the Phyllanthaceae of order Malpighiales is most important with Euphorbiaceae sensu lato as a pantropical family comprised of hundreds of genera and thousands of species. It has several physical characteristics which are the same as Euphorbiaceae sensu stricto. The most important characteristics include unisexual flowers and a syncarpous ovary. Further, the flowers have an axile-apical placentation without pistillode (rudimentary pistil). In the Middle East region, the critical taxonomic review of six important genera from 10 taxa of sub-families Phyllanthaceae and Euphorbiaceae were studied for various characteristics using the latest nomenclature, type citation, and keys for each genus and species. Euphorbia are very rich in natural plant products which have an incredible chemical composition and functional diversity. Compounds were found highly significant and have been the subject of extensive research globally. Further, the genetic composition of Euphorbia is diverse, maturing in various growth forms, cyathial features, and habitats. The molecular characterization of the family Euphorbiaceae also showed a diverse species composition. The members of the family Euphorbiaceae exhibit a palisadal exotegmen with cellular bundles in association with vascular bundles on inner integument as synapomorphies for several major clades. Within current studies on phylogeny and classification of Euphorbia subg. Esula are burning topics comprised of diverse species that make the genus most significant in the kingdom plantae..
PREVALENCE OF CLINICAL SYMPTOMS OF HYPOVITAMINOSIS AMONG STUDENTS
Authors: Merkulova Marina Dmitrievna 
Published: December 2023

Hypovitaminosis is a common problem in the modern world, despite the abundance of pharmaceuticals on the market. To date, about 70% of the population has a lack of any vitamin. Early detection of the first signs of hypovitaminosis will help avoid the occurrence of various pathological processes in the human body.
Purpose. To identify the prevalence of symptoms of hypovitaminosis among students of the Voronezh State Medical University named after N.N. Burdenko.
Materials and methods. A survey was conducted on the basis of the Voronezh State Medical University named after N.N. Burdenko. The questionnaire consisted of blocks of questions that were aimed at detecting the manifestations of hypovitaminosis of individual vitamins.
Results. The study analyzed 80 questionnaires. The age of the respondents varies from 19 to 23 years. Among them are 22 males and 58 females. The study results were statistically processed using a standard method of calculating arithmetic averages using Microsoft Excel 2011.
Thus, to date, it has been revealed that most students are deficient in vitamins V1, C, V12, E and trace elements of calcium, magnesium, iodine and zinc. Complivit, Doppelgerz and effervescent vitamin C tablets were among the three most popular medicines among students for the prevention of hypovitaminosis.
MUTUAL MODIFICATION OF EFFECTS OF METABOLICS AND IMMUNOMODULATORS
Authors: Zemskova Veronika A. 
Published: December 2023

Metabolics, antioxidants, immunomodulators of various origins and mechanisms of action are able to realize a wide range of effects on the pathogenetic units of chronic pyelonephritis. Clinical manifestations in patients with exacerbation of the disease dynamics of normalization of the level of cellular, humoral markers of inflammation, T-B-dependent and cytokine units of immunity, as well as enzymatic and non-enzymatic mechanisms of the antioxidant system (AOS) are subject to correction.
The implementation of these effects is differentiated, dependent on the combination of used metabolic and immunotropic drugs. It specifically includes the possibility of modification by metabolites (Mk, Ml) of the properties of the immunomodulator (If) and immunomodulators (Bf, Sl) of the characteristics of the metabolic (Gp).
The experience of caregiving for children with rare musculoskeletal conditions: A qualitative study in Arthrogryposis Multiplex Congenita
Authors: Elekanachi Rose Uzoma , Lajoie Ariane , Tavukcu SeyhanSena , Snider Laurie , Dahan-Oliel Noemi 
Published: December 2023

Abstract

Background Arthrogryposis Multiplex Congenita (AMC) is a rare musculoskeletal condition with a global health impact. It imposes significant financial burdens on caregivers, affecting them directly, indirectly, and psychologically. Caring for a child with AMC is complex due to their mobility limitations and frequent hospitalizations. Other challenges experienced by caregivers include, but are not limited to, financial strain, job changes, abandonment, and changes in interpersonal relationships. Hence, our study was aimed at exploring the experience of caregivers of children with AMC. Methods This study is part of a global mixed method study. Over 100 caregivers of children aged 0–21 years with AMC participated in the quantitative aspect of this mixed-method study which involved responding to a validated cost of care survey on Qualtrics. Of the 100 participants, 13 caregivers consented to be part of the qualitative aspect of this study which involved a 60-minute semi-structured interview. Individual interviews were semi-structured, conducted remotely with open-ended questions exploring a deeper understanding of the different direct and indirect costs and their impact on the caregivers' lives and caregiving experience. Interviews were subsequently transcribed; a coding scheme was developed drawing from both existing literature and the content of the interviews. The qualitative data were then inductively and deductively analyzed using the coding scheme on the qualitative data analysis software (NVivo). Results and Conclusion Five themes describing the experience of caregivers of children with AMC emerged from the analysis of the qualitative data: 1. Impact of caregiving experience; 2. Cost of childcare; 3. Support system for care; 4. Managing and navigating care; 5. Supporting child’s growth and development. Alongside these themes, recommendations shared by the caregivers included the need for support groups and providing support for youth to prepare them for adolescence. These findings can inform resource allocation, policymaking, and support services for children with rare conditions.
THE INFLUENCE OF PHYSICAL THERAPY ON BALANCE INDICATORS AND THE RISK OF FALLS AS NON-RESPIRATORY MANIFESTATIONS OF THE POST-COVID SYNDROME IN ELDERLY PATIENTS WITH SARCOPENIA
Authors: Rakaieva A.E. , Aravitska M.G. 
Published: December 2023

Мета: визначити ефективність упливу розробленої програми фізичної терапії на динаміку параметрів рівноваги та ризику падіння як нереспіраторних проявів постковідного синдрому в осіб похилого віку з саркопенією.
Матеріал. Обстежено 108 осіб похилого віку. Контрольну групу склали 33 особи, які не хворіли на коронавірусну хворобу. Основну групу склали 75 осіб, які перехворіли на коронавірусну пневмонію, з діагностованим постковідним синдромом. Основну групу 1 склали 34 особи, які проходили реабілітацію в поліклінічних умовах згідно з загальними принципами Протоколу надання реабілітаційної допомоги пацієнтам із COVID-19. Основну групу 2 склав 41 хворий, пацієнти котрої проходили відновлення за розробленою реабілітаційною програмою, що залучала терапевтичні вправи різної спрямованості, функціональні тренування, самостійне виконання комплексу Otago exercise programme, курс загального масажу, ерготерапевтичні методи, рекомендації щодо харчування, навчання пацієнтів із акцентацією на особливостях патогенезу та клінічного перебігу геріатричних синдромів. Ефективність програми оцінювали за динамікою Dynamic Gate Test, Functional Gait Assessment, ABC Scale, Berg Balance Scale, Fall efficacy scale.
Результати. У пацієнтів похилого віку з постковідним синдромом і саркопенією виявлено порушення рівноваги (за Dynamic Gate Test, Functional Gait Assessment), що призвело до погіршення виконання активностей повсякденного життя (за ABC Scale), ризику падіння (за Berg Balance Scale) та страху падіння (за Fall efficacy scale). Розроблена програма реабілітації з урахуванням особливостей перебігу геріатричних синдромів продемонструвала вищу ефективність за статистично значущо кращим результатом показників рівноваги та ризику падіння у хворих із постковідним синдромом порівняно з групою, яка займалась за загальними рекомендаціями клінічного протоколу.
Висновки. Пацієнти похилого віку із постковідним синдромом і саркопенією потребують розробки програм фізичної терапії з урахуванням та корекцією специфіки кожного стану, наявності порушень рівноваги й ризику падіння.
STUDY OF THE INFECTION SPREAD USING MATHEMATICAL MODELING IN PROFESSIONAL HIGHER MEDICAL EDUCATIONAL INSTITUTIONS
Authors: Yaremiy S.I. , Yaremiy I.P. , Moyseenko M.I. , Shulepa S.G. , Lisovska S.A. 
Published: December 2023

Резюме. Підготовка молодшого медичного персоналу вимагає глибокого розуміння не лише основ своєї спеціальності, але й широкого спектра знань, пов'язаних з інфекційними захворюваннями та їх поширенням. Одним із ключових аспектів цієї підготовки є вивчення математичного моделювання поширення інфекцій, яке є важливим інструментом встановлення закономірностей та прогнозування розвитку захворювань. Тому, розгляд підходів до навчання студентів медичних коледжів моделюванню поширення епідемій, зокрема, аналізу процесів поширення вірусу у популяції та факторів, які впливають на швидкість і величину зони його поширення, є актуальною задачею. Дана стаття має за мету ознайомити майбутніх медичних працівників з основними принципами епідеміології та моделювання; допомогти зрозуміти, як вірус чи інфекційне захворювання поширюється всередині популяції; навчити аналізувати, критично оцінювати та інтерпретувати наукові дані та дослідження, не виходячи за рамки базових знань з математики.
У роботі проаналізовано особливості математичного моделювання у медицині та під час навчання майбутніх медичних працівників, та обґрунтовано, що для здобувачів фахової передвищої освіти при моделюванні поширення інфекцій оптимальним є використання найпростіших аналітичних моделей та дещо складнішого імітаційного моделювання за допомогою уже розробленого програмного забезпечення, що обумовлено певним рівнем математичних знань на даному освітньому рівні. Показано, що одним із підходів, які дають можливість досягнення вище вказаної мети, є використання міжнародної безкоштовної навчальної платформи Go-Lab при навчанні молодшого медичного персоналу моделюванню поширення інфекції. Зокрема, моделювання засобами навчальної платформи Go-Lab дає можливість встановити вплив стартових параметрів, що характеризують епідемію, на динаміку поширення вірусу та прогнозувати подальші параметри поширення епідемії і, відповідно, необхідні протиепідеміологічні заходи.