bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of New Surfactants Mono and Bipolar Derived from 1,2,4‐Triazole‐5‐thione.
Authors: Chebabe Driss , Dermaj Ahmed , El Abidine Ait Chikh Zine , Hajjaji Najat , Rico‐Lattes Isabelle , Lattes Armand 
Published: March 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of New Polycyclic β‐Lactams via One‐Pot Enyne Metathesis and Diels—Alder Reactions.
Authors: Desroy Nicolas , Robert‐Peillard Fabien , Toueg Julie , Henaut Charlotte , Duboc Romain , Rager Marie‐Noelle , Savignac Monique , Genet Jean‐Pierre 
Published: March 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Post‐reperfusion changes of monocyte function in coronary blood after extracorporeal circulation
Authors: Sbrana Silverio , Bevilacqua Stefano , Buffa Manuela , Spiller Dario , Parri Maria Serena , Gianetti Jacopo , De Filippis Rossella , Clerico Aldo 
Published: March 2005

AbstractBackgroundNeutrophil and mononuclear cell functional changes represent a hallmark of inflammation during cardiopulmonary bypass and cardiovascular surgery. Knowledge of mechanisms underlying monocyte functional modulation in coronary blood may be useful to develop protective interventions that can limit ischemia/reperfusion injury.MethodsSamples of 13 patients were drawn from venous coronary sinus before cardioplegic arrest and after reperfusion. The following parameters were studied: surface molecules expression (CD18, CD11b, CD44, CD162, CD15s, CD80, CD86, CD16, CD49d, CD29, CD25, HLA‐DR, Toll‐like receptor‐4 [TLR‐4], CXCR1, CCR2, CCR5, CX3CR1), oxidative burst response, monocyte‐platelet conjugates (using antibodies against CD45, CD14, CD41a), and platelet activation (CD62P, PAC‐1). Enzyme‐linked immunosorbent assays were performed to measure levels of interleukin (IL)‐1β, IL‐6, IL‐8, IL‐10, and tumor necrosis factor‐α (TNF‐α).ResultsCoronary reperfusion down‐modulated monocyte molecules expression, especially for CD18 (P = 0.048), CD44 (P = 0.0035), CD49d (P = 0.0029), CD29 (P = 0.032), HLA‐DR (P < 0.0001), TLR‐4 (P = 0.0109), CCR2 (P = 0.0184), CCR5 (P = 0.0396), and CX3CR1 (P < 0.0001). A marginal increase (P = 0.062) of a normalized adhesion index between monocytes and platelets was observed at reperfusion. No variations were detected for the monocyte oxidative burst and platelet activation. Increased levels of IL‐6 (P = 0.013), TNF‐α (P = 0.0272), and IL‐10 (P = 0.0008) were measured after cardioplegia.ConclusionsThe lack of CD11b and CD25 variations and of the oxidative burst exclude monocyte activation at reperfusion. The high after‐cardioplegia level of IL‐10, the decreased expression of HLA‐DR and TLR‐4, and the absence of IL‐1β and IL‐8 suggest an IL‐10–mediated functional depression of monocyte, including their adhesive and migratory capacities. The lack of an after‐cardioplegia orientation toward IL‐10 producing a “macrophage‐like” CD14+/CD16+ phenotype might mean that myocardial infiltrating lymphocytes are the main source of IL‐10. Moreover, the increased after‐cardioplegia levels of IL‐6 and TNF‐α might be due to myocardial and endothelial activations. The increased adhesion index between monocyte and platelets, without receptor variations, suggests a monocyte membrane modification induced by extracorporeal circulation. © 2005 Wiley‐Liss, Inc.
Residual insulin secretion at diagnosis of type 1 diabetes is independently associated with both, age of onset and HLA genotype
Authors: Petrone A. , Galgani A. , Spoletini M. , Alemanno I. , Di Cola S. , Bassotti G. , Picardi A. , Manfrini S. , Osborn J. , Pozzilli P. , Buzzetti R. 
Published: March 2005

AbstractBackgroundWe investigated whether residual insulin secretion and metabolic derangement at diagnosis of type 1 diabetes (T1DM) are influenced by human leukocyte antigens (HLA) class II genes.MethodsEight hundred and seventy‐one T1DM consecutive Caucasian patients were typed for HLA class II genes. In 300 of these patients, glycated haemoglobin, insulin requirement, baseline C‐peptide and body mass index (BMI) Z‐score were measured at clinical diagnosis. The effect of the HLA genotypes on the quantitative variables was investigated using multiple linear regression. The beta coefficient regression of the age at onset and HLA genotypes were standardized to compare their specific importance for C‐peptide levels.ResultsThe HLA genotypes were divided in high‐, moderate‐ and low‐risk categories. The frequency of high‐risk genotype, DRB1*03‐DQB1*0201/DRB1*04‐DQB1*0302, decreased with increasing age of onset (p < 0.0001, χ2 linear trend). The presence of the high‐risk genotype was independently associated with lower C‐peptide levels at diagnosis (p = 0.002). In the regression analysis of C‐peptide levels, the standardized beta coefficient for age of onset and high risk compared to low‐risk genotypes showed similar results (0.27 and 0.24 respectively). There was a positive association between age of onset and C‐peptide (p < 0.0001) and a negative association between age of onset and insulin requirement (p < 0.0001).ConclusionsThe degree of beta‐cell destruction at diagnosis of T1DM is independently associated with both, age of onset and HLA genotypes, the two variables exert a similar quantitative effect on residual beta‐cell function at diagnosis. Copyright © 2005 John Wiley & Sons, Ltd.
Microwave‐assisted from synthesis of 2‐arylamino‐2‐imidazolines on a solid support
Authors: Genc Murat , Servi Süleyman 
Published: March 2005

AbstractAn efficient synthesis of 2‐arylamino‐2‐imidazolines from dimethyl N‐aryldithioimidocarbonates and ethylenediamine on solid support under microwave irradiation has been developed. The reaction time has been reduced from hours to minutes with improved yields as compared to conventional heating. Their piperidin‐4‐ylmethyl and morpholin‐4‐ylmethyl derivatives were synthesized by treatment with formaldehyde and piperidine or morpholine. © 2005 Wiley Periodicals, Inc. Heteroatom Chem 16:142–222, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20081
1,3,5‐Triamino‐1,3,5‐trideoxy‐cis‐inositol, a Ligand with a Remarkable Versatility for Metal Ions. Part XIII
Authors: Hegetschweiler Kaspar , Egli André , Herdtweck Eberhardt , Herrmann Wolfgang A. , Alberto Roger , Gramlich Volker 
Published: March 2005

AbstractThe two neutral complexes [Re(CO)3(H−1taci)] (1) and [ReO3(H−1taci)] (2) (taci=1,3,5‐triamino‐1,3,5‐trideoxy‐cis‐inositol) were synthesized from the conventional ReI and ReVII precursors (Et4N)2[ReBr3(CO)3] and [ReO3(OSnMe3)]. The crystal structures of 1 and 2, which were determined by single crystal X‐ray analysis, are virtually isomorphous. Both compounds crystallize in the orthorhombic space group Pnma, Z=4; 1: a=14.806(3), b=8.466(2), c=9.781(2) Å, 2: a=13.050(2), b=8.732(1), c=9.061(1) Å. In both complexes, the monodeprotonated H−1taci ligand is bonded to the Re center in an N,O,N‐coordination mode. The resulting molecular Cs symmetry is retained in the crystal structure and confirmed by IR spectroscopy of solid‐state samples. The observed binding mode of the ligand is discussed in terms of steric and electronic effects.
Aqueous Organometallic Chemistry. Synthesis and Solution Equilibria of Trisodium Carbonylchlorotris[3‐(diphenylphosphino‐κP)benzenesulfonato]hydridoruthenate(3−) ([RuH(Cl)(CO){m‐(Ph2P)C6H4SO3Na}3]) and Trisodium Aquacarbonyltris[3‐(diphenylphosphino‐κP)benzenesulfonato]hydridoruthenate(2−) Tetrafluoroborate(1−) ([RuH(CO)(H2O){m‐(Ph2P)C6H4SO3Na}3] [BF4])
Authors: Papp Gábor , Horváth Henrietta , Kathó Ágnes , Joó Ferenc 
Published: March 2005

AbstractAn improved procedure for the preparation of the known H2O‐soluble hydrogenation and hydroformylation catalyst, [RuH(Cl)(CO)(mtppms)3] (mtppms=meta‐monosulfonated triphenylphosphine) was developed. In contrast to the methods reported earlier, this synthesis yields the complex free of mtppms impurities. 1H‐ and 31P{H}‐NMR measurements revealed that in aqueous solution, [RuH(Cl)(CO)(mtppms)3] reversibly dissociated to give [RuH(CO)(H2O)(mtppms)3]+ (Scheme). The equilibrium constant of this dissociation was determined as 9.8⋅10−2 M at 293 K. Such a dissociation was not observed in MeOH but took place to varying degrees in MeOH/H2O mixtures of varying composition. [RuH(CO)(H2O)(mtppms)3][BF4] was also obtained on an independent synthetic route: by ligand exchange in [RuH(CO)(NCMe)2(PPh3)2][BF4] (Scheme). The results may help the understanding of the mechanisms of reactions catalyzed by [RuH(Cl)(CO)(mtppms)3] in aqueous solutions or in aqueous–organic biphasic systems.
H5dotasa (=(αRS)‐α‐(Carboxymethyl)‐1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic Acid), an Asymmetrical Derivative of H4dota (=1,4,7,10‐Tetraazacyclododecane‐1,4,7,10‐tetraacetic Acid) Substituted at One Acetate Pendant Arm: 1H‐NMR and Potentiometric Studies of the Ligand and Its Lanthanide(III) Complexes
Authors: André João P. , Brücher Ernö , Kiraly Robert , Carvalho Rui A. , Mäcke Helmut , Geraldes Carlos F. G. C. 
Published: March 2005

AbstractThe ligand H5dotasa (=(αRS)‐α‐(carboxymethyl)‐1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid) is a H4dota‐like macrocyclic ligand with a carboxymethyl CH2COOH substituent at the C(α) atom of one of the four acetate pendant arms of H4dota (=1,4,7,10‐tetraazacyclododecane‐1,4,7,10‐tetraacetic acid), present as a racemic mixture of (αR) and (αS) enantiomers. The protonation constants of the ligand were determined by potentiometry, giving values close to those of H4dota except for the extra pK3 value of 5.35 assigned to protonation of the extra carboxylate group in the α‐substituted (=succinic acid) pendant arm. The 1H‐NMR spectra of H5dotasa at different pH values are too complex to allow the determination of its microscopic protonation scheme, due to the presence of multiple isomeric structures in solution. The thermodynamic stability constant of its Gd3+ chelate was determined by a potentiometric method, and the value obtained, log KML=27.2 (0.2), is higher than for the [Gd(dota)(OH2)]− complex. The solution structure of the asymmetric Ln3+ chelates of dotasa was studied by 1H‐NMR spectroscopy, indicating the presence of four isomers, corresponding to the combination of the antiprismatic (M) and twisted antiprismatic (m) helicities of the pendant arms and to the (αR) and (αS) configurations at the substituted pendant arm. The m/M isomer ratio decreases along the lanthanide series, with the m isomer decreasing from 90% at La to ca. 50% from Eu–Lu. This shows that the expected m isomer population of the [Gd(dotasa)(OH2)]2− complex is higher than for the unsubstituted [Gd(dota)(OH2)]− (ca. 15%) but lower than for a Gd3+ chelate of an α,α′,α″,α′′′‐tetrasubstituted (RRRR)‐configurated dota (ca. 70%). Thus the stabilization of the m isomer by C' monosubstitution at the dota acetate pendant arm in [Gd(dotasa)(OH2)]2− is responsible for its increased H2O‐exchange rate and higher relaxivity.
Study on the self‐setting property and the in vitro bioactivity of β‐Ca2SiO4
Authors: Gou Zhongru , Chang Jiang , Zhai Wanyin , Wang Junying 
Published: March 2005

AbstractThis study sought to investigate the physical and chemical properties of β‐dicalcium silicate (β‐Ca2SiO4) in order to evaluate its use as an injectable bioactive cement filler. Workable β‐Ca2SiO4 pastes with a liquid‐to‐powder (L/P) ratio of 1.0–1.2 could be injected for 10–30 min (nozzle diameter 2.0 mm) and enabled initial setting times of 60–180 min. The setting process yielded cellular structures with compressive strengths of 4.8–28.8 MPa after 2–28 days. The paste was soaked in simulated body fluid (SBF), and the results demonstrated that it exhibited a moderate degradation and could induce carbonated hydroxyapatite formation. The ionic products of the paste dissolution enhanced a proliferative response of fibroblasts compared with the cells cultured alone, and this cement could also support adhesion and spreading of the mesenchymal stem cells. Finally, with the use of gentamicin as a model drug, it was found that a high dose of drug release from the paste was maintained for 14 days, and there was a sustained release over 4 weeks. This combination of properties indicates that the novel β‐Ca2SiO4 cement might be suitable for potential applications in the biomedical field, preferentially as materials for bone/dental repair and controlled drug‐delivery systems. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater
Exploring the potential energy surface of retinal, a comparison of the performance of different methods
Authors: Blomgren Fredrik , Larsson Sven 
Published: March 2005

AbstractThe ground state structure of retinal has been investigated. We found that DFT and CASSCF produce different results for the bond length alternation in a model system of retinal. Quantum mechanics/molecular mechanics calculations including the closest surrounding amino acids have been performed, using DFT and CASSCF to calculate the structure of retinal in the protein cavity. The planarity of the retinal molecule is affected by the surrounding protein. DFT and CASSCF produce different twist angles. The difference between CASSCF and DFT appears to be related to the positively charged nitrogen of the Schiff base, which leads to different π‐bond orders produced by the two methods. © 2005 Wiley Periodicals, Inc. J Comput Chem 26: 738–742, 2005
Site‐select procedure for non‐palpable breast lesions: Feasibility study with a 15‐mm cannula
Authors: Barranger Emmanuel , Marpeau Olivier , Chopier Jocelyne , Antoine Martine , Uzan Serge 
Published: March 2005

AbstractBackgroundAs screening mammography becomes more commonplace, increasing numbers of non‐palpable breast lesions are being found. The aim of this prospective study was to evaluate the feasibility, utility, and patient‐perceived cosmesis and satisfaction of the Site‐Select procedure in women with non‐palpable breast lesions.MethodsThirty‐two consecutive patients underwent the Site‐Select procedure, performed under local anesthesia by the same surgeon. The Site‐Select procedure was included in a protocol for small (<15 mm) breast imaging reporting and data system (BI‐RADS) grade 3 and 4 breast lesions. The pathologic diagnosis, specimen size, length of the procedure, perioperative and postoperative complications, subsequent interventions, patient satisfaction, and esthetic results were documented.ResultsThe Site‐Select procedure was successful in all 32 patients (mean age, 56 years; range, 44–79 years). Mammographic lesions corresponded to microcalcifications in 21 patients, microcalcifications with architectural distortion in 4 patients, microcalcifications with nodules in 2 patients, and architectural distortion alone in 5 patients. The Site‐Select procedure was used on an outpatient basis. Carcinomas were diagnosed in five patients (15.6%). No complications occurred during the procedure. The only postoperative complication was a hematoma, which did not require surgical drainage. No missed cancers were detected by follow‐up mammography (mean 8 months later; range, 1–18 months). The esthetic results and patient satisfaction were excellent.ConclusionsThis study demonstrates that the Site‐Select procedure is an effective diagnostic method in selected cases. It has a low complication rate, high patient satisfaction, and excellent esthetic results. J. Surg. Oncol. 2005;90:14–19. © 2005 Wiley‐Liss, Inc.
Vegetation index differencing and linear regression for change detection in a Swedish mountain range using Landsat TM® and ETM+® imagery
Authors: Nordberg M.‐L. , Evertson J. 
Published: March 2005

AbstractThis paper describes the extent to which the normalized difference vegetation index (NDVI) in combination with image regression used on satellite data can indicate vegetation cover decreases caused by increased exploitation of Swedish mountains. The methods outlined in this study give a basis for detection of less sustainable mountain ecosystems by using as an indicator bare patches of humus or soil where none existed previously. Landsat 5 TM® data from 1984 and 1994 and Landsat 7 ETM+® data from the year 2000 were used in the study. The results show that the NDVI significantly separates areas with vegetation cover decrease from areas with no vegetation cover decrease in sensitive, high‐latitude mountain ecosystems, such as mountainous dry heath communities. Copyright © 2005 John Wiley & Sons, Ltd.
Land degradation indicators in Kuwait
Authors: Al‐Awadhi J. M. , Omar S. A. , Misak R. F. 
Published: March 2005

AbstractIn arid regions, such as Kuwait, land degradation is exacerbated by the scarcity of rainfall and intensive wind and water erosion. In Kuwait seven land degradation indicators were recognized and described. These are: soil erosion by wind and/or water; deterioration of vegetation cover; soil crusting and sealing; soil compaction; soil contamination by oil; and soil salinization. Four areas in Kuwait, namely Al Mutlaa, Ras Al‐Sabiyah, Sulaibiyah and Ahmadi‐Al‐Dahr, were studied to assess the extent and magnitude of land degradation. Remote sensing images and the following parameters were investigated in each area: vegetation cover; soil bulk density; infiltration capacity; and top soil resistance. The areas showed significant variations in vegetation cover, and increase in erosion by wind and water and soil compaction. Based on the percentage of vegetation cover and the physical properties of the soil, three classes of land degradation are identified. These classes are: severe; moderate; and slight. Overgrazing was shown as a main cause of land degradation, followed by military operations, quarrying and camping. Copyright © 2005 John Wiley & Sons, Ltd.
Quality assurance of test pieces as a basis for adequate significance of test results
Authors: Badenheim D. , Hoffmann M. J. , Oberacker R. 
Published: March 2005

AbstractThe relevance of the centralised acquisition of test material needed within the SFB and the quality assurance carried out for this material is discussed. Results from quality inspections for components from commercial ceramic materials are reported to demonstrate this relevance. The surface characteristics of these components are compared to surfaces resulting from hard machining operations, carried out under defined conditions in the own laboratory. From the applied mechanical examinations, the crack growth behaviour of Al2O3 evaluated by various methods is compared. Finally, the raw part production and also the hard machining of test series from newly developed sialon ceramics is presented. These materials are considered for sliding applications.
Stereotypical movements and frontotemporal dementia
Authors: Mendez Mario F. , Shapira Jill S. , Miller Bruce L. 
Published: March 2005

AbstractStereotypical movements are characteristic of autism or mental retardation but can also occur in patients with dementia, particularly frontotemporal dementia (FTD). In this study, we administered the Abnormal Involuntary Movement Scale (AIMS) to 18 patients with FTD and to 18 patients with the most common form of dementia, Alzheimer's disease (AD). The AIMS scores were gathered at the initial presentation of patients who had not received antipsychotic medications. Compared to the AD patients, the FTD patients had significantly more stereotypical movements, including frequent rubbing behaviors and some self‐injurious acts. All the FTD patients with stereotypical movements had compulsive‐like behaviors, suggesting a similar pathophysiologic cause, and most had a decrease in their stereotypical movements with the administration of sertraline, a serotonin selective reuptake inhibitor. © 2005 Movement Disorder Society
Concanavalin a inhibits pathophysiological effects of anti‐ganglioside GQ1b antibodies at the mouse neuromuscular synapse
Authors: Bullens Roland W. M. , Halstead Susan K. , O'Hanlon Graham M. , Veitch Jean , Molenaar Peter C. , Willison Hugh J. , Plomp Jaap J. 
Published: March 2005

AbstractAnti‐GQ1b antibodies are present in the Miller Fisher syndrome (MFS), a monophasic neuropathy characterized by ataxia, areflexia, ophthalmoplegia, and sometimes cranial muscle weakness. We have previously shown, at the mouse neuromuscular junction (NMJ) ex vivo, that anti‐GQ1b antibodies, through complement classic pathway activation, block synaptic transmission in a way that resembles the effect of the pore‐forming α‐latrotoxin (αLTx). In order to clarify the mechanism of these αLTx‐like effects, including possible involvement of the alternative and mannose‐binding protein complement pathways, we studied the effects of concanavalin A (ConA), a lectin known to block the action of αLTx, immunoglobulins, and early complement components. With electrophysiological, immunohistological, and bioassay experiments, we showed that the αLTx‐like effects of anti‐GQ1b antibody and complement were inhibited by pre‐ and coincubation with ConA. However, ConA was not able to inhibit evolution of αLTx‐like effects when coincubated upon addition of complement at NMJs that had already bound anti‐GQ1b antibody. Our data suggest that the mannose‐binding protein pathway is not involved in the αLTx‐like effect and that the inhibiting effect of ConA principally arises through interference with presynaptic binding of anti‐GQ1b antibody. In control experiments, ConA prevented the neuroexocytotic effects of αLTx, indicating that αLTx receptors were inhibited under these conditions. We conclude that, although the physiological effects at the NMJ of anti‐GQ1b antibody and αLTx are very similar, the activity of anti‐GQ1b antibody is not mediated through activation of αLTx receptors, but rather is caused by direct presynaptic membrane damage through classic complement pathway activation. Muscle Nerve, 2005
One‐pot synthesis of linear and branched poly(amide aspartimide)s with good solubility in organic solvents
Authors: Wu Chuan‐Shao , Tsai Shr‐Hau , Liu Ying‐Ling 
Published: March 2005

AbstractLinear and branched poly(amide aspartimide)s were prepared through the reaction of 4,4′‐diaminodiphenylmethane with 4‐maleimidobenzoic acid and 5‐maleimidoisophthalic acid, respectively. The synthesis was performed through a one‐pot operation by means of the Michael addition reaction between amine and maleimide groups and the dehydration condensation reaction between amine and carboxylic acid groups. The obtained polymers exhibited fairly good solubility in aprotic polar solvents at room temperature and in pyridine, tetrahydrofuran, acetone, and chloroform upon heating. High glass‐transition temperatures (≥225 °C) and thermal stability above 360 °C were found for the polymers. © 2005 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 43: 1923–1929, 2005
Atomic force microscopy study on blend morphology and clay dispersion in polyamide‐6/polypropylene/organoclay systems
Authors: Chow W. S. , Ishak Z. A. Mohd , Karger‐Kocsis J. 
Published: March 2005

AbstractThe phase structure and clay dispersion in polyamide‐6(PA6)/polypropylene(PP)/organoclay (70/30/4) systems with and without an additional 5 parts of maleated polypropylene (MAH‐g‐PP) as a compatibilizer were studied with atomic force microscopy (AFM). AFM scans were taken from the polished surface of specimens that were chemically and physically etched with formic acid and argon ion bombardment, respectively. The latter technique proved to be very sensitive to the blend morphology, as PP was far more resistant to ion bombardment than PA6. In the absence of the MAH‐g‐PP compatibilizer, the organoclay is located in the PA6 phase; this finding is in line with transmission electron microscopic results. Further, the PP is coarsely dispersed in PA6 and the adhesion between PA6 and PP is poor. The addition of MAH‐g‐PP resulted in a markedly finer PP dispersion and good interfacial bonding between PA6 and PP. In this blend, the organoclay was likely dispersed in the PA6‐grafted PP phase. © 2005 Wiley Periodicals, Inc. J Polym Sci Part B: Polym Phys 43:1198–1204, 2005