bluuebunny/crossref_metadata_2025_split huggingface dataset:
Serbest fetal DNA fraksiyonu plasental problemlere bağlı gebelik sonuçlarında değişir mi?
Authors: AKAR Bertan , KÖLE Emre , ÖZCAN Canan , ÇAKIR KÖLE Merve 
Published: October 2023

Amaç: Cff-DNA’nın non-invazif tanı uygulamaları dışında, bu biyobelirtecin preeklampsi, IUGR, preterm doğum gibi önemli obstetrik komplikasyonları belirlemede yerini araştırmak.
Yöntemler: Çalışmamız eylül 2019-mart 2020 tarihleri arasında, kliniğimize başvuran 10-24. Gebelik haftaları arasında kendi isteği, ileri anne yaşı olan (≥40) ve ikili testte artmış trizomi 13, 18 ve 21 riski nedeniyle serbest fetal DNA analizi (HarmonyTM Prenatal Test; Ariosa Diagnostics Inc., San Jose, Calif., USA) yapılan 131 hastalarda tek merkezli retrospektif çalışma olarak planlandı.
Bulgular: Çalışmamızda hastaların 10’ unda (%8,1) oligohidramnios, 10’ unda (%8,1) gestasyonel diyabet, 7’ sinde de (%8,6) preeklampsi gözlenmiştir. 2 hastada da (%1,2) dekolman plasenta izlenmiştir. 10-24. gebelik haftaları arası ölçülen hücre dışı fetal DNA fraksiyonlarının artmış düzeyleri IUGR ile sonuçlanan gebelikleri öngörmede anlamlı bulunmuştur (p< 0.01). Diğer gebelik sonuçları ( preeklampsi, GDM, preterm eylem, oligohidroamnios, dekolman plasenta ) ve hücre dışı fetal DNA fraksiyon düzeyleri ile anlamlı ilişki bulunamamıştır.
Sonuç: Cff-DNA’nın prenatal taramada bir dizi değerli uygulamaya sahiptir ancak gebelik komplikasyonlarını öngörmede cff-DNA’nın düzeyleri ile ilişkisi klinik uygulamada henüz yeri netleşmemiştir. Bu nedenle çalışmalar, cff-DNA’nın potansiyel öngörüsü ve tanısal uygulamalarını belirlemek için gebelikteki patolojik koşullar altındaki düzeylerinin belirlemesini amaçlamalıdır.
Inhibitory Effect of Cell Phones Against Human Breast Cancer and Myeloid Leukemia Cells Proliferation in Culture Media
Authors: BOĞA Bircan , AKBULUT Merve , MAYTALMAN Erkan , KOZANOĞLU İlknur 
Published: October 2023

Objective: There is current news that emerges regarding the relationship between the magnetic effects of cell phones and some types of cancer. In spite of the studies carried out, the level of evidence of this news is low, and also the relationship between the magnetic effects of cell phones and other types of cancer is not certain except for brain cancer. In this study, it is aimed at examining the effects of magnetic field of cell phones on the samples of breast cancer human myeloid leukemia cell growth.
Methods: In the study, breast cancer MCF-7 and leukemia K562 cell lines were used as the source of cancer cell. During the six-day cell culture, cancer cells were subjected to the effects of cell phone by using a telephone call program (Automated outbound call software). The system made 6 calls for 1 minute for each call once in 144 minutes from fixed line. The number of cultured cells and proliferation capacities of the two types of tumor cells in the control and experimental groups were assessed.
Results: The number of cancer cells, which were subjected to the effects of cell phone as a result of the culture of tumor cells, was found lower when compared with control group (7500000 ± 100000 vs 6625000 ± 225000 for MCF-7; 15412500 ± 112500 vs 13700000 ± 250000 for K562; P < 0.05 for both). In MTT test, it was found out that two types of cell proliferation was inclined to slow down with the effect of cell phone.
Conclusion: The results can be translated that cell phone may inhibit neoplastic transformation, and this observation may promote to initiate a new clinical studies both for healthy people and for patients with cancer.
KEEP IN MIND OTHER CAUSES THAN INTRINSIC SPHINCTER DYSFUNCTION IN POST-PROSTATECTOMY INCONTINENCE
Authors: YILDIZ Hüseyin Alperen , SOGUTDELEN Emrullah 
Published: October 2023

Objective: This study aims to determine the causes of urinary incontinence and accompanying bladder pathologies in patients with persistent incontinence 12 months after radical prostatectomy.
Methods: Thirty-four patients who underwent open radical retropubic prostatectomy (RRP) due to localized prostate cancer and incontinent after surgery between January 2015 and December 2020 and underwent urodynamic study (UDS) were retrospectively reviewed. All UDSs were performed according to the ICS protocol of good urodynamic practice and assessed by the same doctor. Patients were assessed by demographic and clinical parameters including age, body mass index (BMI), comorbidity, preoperative PSA level, prostate volume (PV), transrectal prostate biopsy Gleason score, clinical stage, pathological ISUP grade, pathological stage, lymph node positivity, international consultation on incontinence questionnaire-short form and subjective questionnaire for daily pad use.
Results: Urodynamic studies showed that 29 patients (85.2%) had intrinsic sphincter deficiency (ISD). Nine (26.4%) of 29 patients with ISD had a secondary diagnosis of overactive bladder (OAB), impaired detrusor contractility (IDC) and OAB+IDC 9 (11.6%), 4 (11.6%), 1 (2.9%), respectively. Nineteen patients (55.8%) had a sole diagnosis of ISD, whereas 15 patients (44.1%) had another primary diagnosis or a secondary diagnosis other than ISD.
Conclusion: Although ISD is the most common cause of persistent urinary incontinence in patients after radical prostatectomy, it should be taken into account that overactive bladder and impaired detrusor contractility are also accompanied by a significant proportion of patients.
Antibiotic resistance of acinetobacter strains in our intensive care unit : a retrospective study
Authors: KARAKOÇ Ebru , AYYILDIZ Ayşe , YELKEN Birgül 
Published: October 2023

Objective: Antibiotic resistance development in the treatment of acinetobacter infection is a serious health care problem and responsible for high mortality in intensive care units (ICU). In our study, it was aimed to determine rates of antibiotics resistance of Acinetobacter strains isolated from various samples in our ICU.
Methods: We examined the records of acinetobacter isolates and antibiotics resistance for one year follewed up in our ICU. The samples from different patients and different type of samples of the same patients were evaluated.The data was analyzed with SPSS for Windows version 23.0. Categorical variables were expressed in terms of numbers and percentage.
Results: 50% of the samples were isolated from tracheostomy.96.4% of the 138 isolates were A. Baumanii and 3.6% were the other strains.We found high resistance to all of antibiotics except colistin(3.6%) and tigecycline (13.1%).
Conclusion: Acinetobacter is the most important opportunistic human pathogen causing fatal nosocomial infections because of its ability of develop resistance new antibiotics overly fast. Compared to the results reported from Dicle University Hospital in south east of our country it seems that antibiotics especially cholistin resistance ratio in our ICU is different. It is important to remember that antibiotic susceptibility may vary in regions, hospitals even clinics, and resistance development should be constantly detected to make the appropriate initial therapy until deescalation.
Assessment of endothelial dysfunction and vascular stiffness after cholecalciferol according to dialysis modality
Authors: AYTAC Mehmet Baha , ÖZGÜR Merve Aktaş , DOĞAN Kenan , DEVECİ Murat , KAYABEY Özlem , BEK Kenan 
Published: October 2023

ABSTRACT
Objective: The risk of developing cardiovascular disease (CVD) increases significantly in children with chronic kidney disease (CKD) especially with low serum 25- hydroxyvitamin D (25OHD) levels. Herein; we aimed to compare the effects of vitamin D deficiency and the impact of cholecalciferol treatment on endothelial functions and vascular stiffness in children with CKD receiving hemodialysis (HD), peritoneal dialysis (PD) and non- dialysis(ND).
Methods: 7 HD, 7 PD and 27 ND patient groups consisting of 41 children totally with low 25OHD levels were compared among each other in regards of biochemical parameters, flow-mediated dilatation(FMD) and local arterial stiffness before and after a single dose of 300.000 units of cholecalciferol treatment.
Results: There was no difference in FMD and local arterial stiffness values between HD, PD and ND patient groups before vitamin D supplementation. Significant increase in endothelium-dependent FMD was observed in all patient groups after intervention with cholecalciferol; however the improvement in endothelium-independent FMD and local arterial stiffness measurements was demonstrated in patients with PD and ND. Baseline parathormon level was higher in patients on dialysis; at the end of the study, significant decrease was detected only in patient group not receiving diaysis.
Conclusions: Endothelial dysfunction and impaired vascular stiffness were determined in children with CKD with low 25OHD levels regardless of the disease severity.. Recovery with cholecalciferol therapy revealed that vitamin D deficiency should be corrected even in early stages of CKD to prevent the development of CVD
Elektif Koroner Arter Bypass Cerrahisinde Traneksamik Asit Uygulama Tekniğinin Etkinliği
Authors: İNDELEN Cenk 
Published: October 2023

Amaç
Bu çalışmanın amacı, elektif koroner arter bypass cerrahisi geçiren hastalarda traneksamik asitin kardiyopulmoner bypass öncesi ve sonrası uygulanmaya başlanmasının etkilerini değerlendirmektir. Birincil güvenlilik son noktası, ameliyat sonrası yoğun bakım erken miyokart enfarktüsü, inme, tromboemboli (arteryal/venöz) olayları değerlendirmektir. Birincil etkinlik son nokta, eritrosit süspansiyonu transfüzyonu miktarı ve yoğun bakım kalış süresine etkiyi ölçmektir.
Yöntem
Ocak 2002 ile Aralık 2007 yılları arasında 3729 izole elektif koroner arter bypass greft operasyonu retrospektiftif olarak incelendi. 300 hasta çalışmaya dahil edildi. Örneklem büyüklüğü her grupta 100 hasta olacak şekilde oluşturuldu. Grup 1 kontrol grubuna traneksamik asit uygulaması yapılmadı, Grup 2 cerrahi insizyondan 20 dakika önce traneksamik asit 30mg/kg bolus dozunda uygulandı ve kardiyopulmoner bypass sonunda, protamin verilmesi bittikten 10 dakika sonra 10mg/kg dozunda başlandı, 4 saat infüzyon ile verildi. Grup 3 kardiyopulmoner bypass sonunda, protamin verilmesi bittikten 10 dakika sonra traneksamik asit 30mg/kg bolus dozunda uygulandı ve 10mg/kg dozunda başlandı, 4 saat infüzyon ile verildi. İstatistiksel olarak ANOVA analiz,post hoc Tukey HSD, Pearson chi kare, Fisher’s exact yöntemleri kullanıldı.
Bulgular
Traneksamik asit uygulama farklılığı postoperatif kanama miktarını anlamlı etkisi olmadı. Yoğun bakım kalış süresini etkilemedi. Kardiyopulmoner bypass sonrası traneksamik asit uygulamasının eritrosit transfüzyonunda olumlu anlamlı etkisi oldu. Ancak aynı grupta ciddi bir komplikasyon olan inme daha sık görüldü.
Sonuç
Traneksamik asit uygulama ve dozları ile ilgili ortak bir klinik yaklaşım yoktur. Kılavuzlar transüzyon miktarının azaltılması ve “Hasta Kan Yönetimi” uygulamaları için traneksamik asit kullanımını önermektedir. İnme komplikasyonu tedirgin edicidir
Pulmoner Hydatid Cyst Surgical Treatment, Single Center Experience
Authors: ELİCORA Aykut , SEZER Hüseyin Fatih 
Published: October 2023

Objective: Lung hydatid cyst is an infectious disease caused by the parasite Echinococcus granulosus. Surgery is the main treatment of the disease in lung hydatid cysts. In our article, we aimed to share our experiences with our patients who underwent surgical treatment for hydatid cysts of the lungs.
Methods: The data of 41 patients who underwent surgical treatment for pulmonary hydatid cysts in our clinic were analyzed retrospectively. The factors affecting the success of surgical treatment were analyzed.
Results: Eighteen (43.9%) of the patients were male and 23 (56.1%) were female. There was no statistically significant difference between the size groups in terms of length of hospital stay (p=0.070). No statistically significant correlation was found between the number of lesions and postoperative complications (p=0.367).
Conclusion: Lung hydatid cysts are a public health problem that can be seen in all age groups. Although different symptoms and complications related to the disease are encountered in lung hydatid cysts, surgery is an effective treatment method with low recurrence, morbidity and mortality.
Triple Jump Ability: The Effect Of Single Leg Speed Hop Training Method on High School Students
Authors: FADHOLI M. NUR 
Published: October 2023

The purpose of the study. This research was motivated by the results of the triple jump carried out by the students of class X SMAN 2 Tapung Hilir not optimal and less precise in its implementation. The triple jump is an athletic sport in the form of jumping, lifting the legs up and forward in an effort to carry the point of weight as long as possible in the air.
Materials and methods.. Methods This research uses an experimental method with One Group, namely Pre-test and Post-test Design. The data collection technique was saturated sampling with inclusion and exclusion criteria. Data analysis in this study used the Wilcoxon test, Paired Sample T-test.
Results. Data analysis in this study used the Wilcoxon test, Paired Sample T-test. Research results based on the statistical output "Test Statistics", it is known that Asymp.Sig (2-tailed) is worth 0.001. Because the value of 0.001 is smaller than <0.05.
Conclusions. The conclusion in this study is that there is a significant effect between the single leg speed hop exercise method and the triple jump ability of the students of SMAN 2 Tapung Hilir.
Pengembangan Media Pembelajaran Scrapbook untuk Meningkatkan Hasil Belajar Siswa
Authors: Khoirin Lukman 
Published: October 2023

Rendahnya minat belajar siswa dalam pembelajaran karena kurangnya pemanfaatan media berakibat pada kurangnya peningkatan hasil belajar siswa. Penelitian ini mengembangkan media scrapbook untuk meningkatkan hasil belajar pada pembelajaran matematika materi bilangan pecahan .Penelitian ini bertujuan untuk meningkatkan hasil belajar pada pembelajaran matematika materi bilangan pecahan denagn menggunakan media scrapbook di kelas III SD Islam Darussalam Kedungrejo Sumberrejo. Media scrapbook adalah salah satu media pembelajaran jenis 3 dimensi. Media ini berupa handmade yang dibuat dari kertas asturo maupun kertas karton. Subjek penelitian ini yaitu seluruh siswa kelas III SD Islam Darussalam Kedungrejo Sumberrejo dengan jumlah 39 siswa 18 laki-laki dan 21 perempuan . Penelitian ini menggunakan penelitian tindakan kelas dengan model desain Kemmis & Mc. Taggart, Teknik pengumpulan data pada penelitian ini adalah observasi, tes, dokumentasi. Hasil penelitian pra siklus mendapatkan persentase sejumlah 45,15%. Dan siklus pertama mendapatkan persentase sejumlah 57,35% pada siklus kedua mendapatkan persentase sejumlah 73,25%. Dapat disimpulkan bahwa hasil penelitian pengembangan media scrapbook dalam pembelajaran matematika materi bilangan pecahan dapat meningkatkan hasil belajar kelas III SD Islam Darussalam Kedungrejo Sumberrejo. Media pembelajarannya juga dapat diterima siswa terbukti dengan semangat siswa dan respon siswa.
Effect of Spirulina and Probiotic on Growth Performance of Japanese Quail
Authors: Alhussaini Ruaa , Bahaa A. Alsereah  , Assad H. Eissa  
Published: October 2023

The aim of current project is to fortify the quail feeds with various types of supplements such as spirulina, Used as a substitute for Prob. & study the growth performance to recognize the best formula of spirulina for best production. untreated was feed on standard diet, Spirulina group was feed with Spirulina , Probiotics complex group was feed with probiotics complex, Mix Spirulina with probiotic complex group was feed with above Spirulina & probiotic. complex. BW, BWG, FI & FCE were daily recoded. Results noted at highest significant increase (P≤0.05) for the addition of spirulina occurred in the average body weight of Japanese quail compared to the control and other treated groups. The highest significant increase (P≤0.05) occurred in the BWG rates of birds treated with the addition of spirulina for weeks (1 and 4) and the cumulative (1-6) weeks. the highest rate (p≤0.05) of feed consumption was recorded in the group of birds treated with spirulina for weeks (2, 3, 4, 5, and 6). and the cumulative feed consumption rate from (1-6) weeks compared with the other treatments and the control group. Rresults showed FCE rates recorded a significant improvement in adding spirulina during (1,2,3,4,6) weeks and the cumulative feed conversion efficiency average (1-6) weeks for birds. From this research, we concluded that adding spirulina to quail diets improved productive traits.
morphological Study of the Small Intestine in the Geese (Anser anser).
Authors: Radwan Zeena 
Published: October 2023

This study aimed to identify morphological of the small intestine in adult geese. Six healthy geese were bought from the Baghdad local market, their age from (2- 5) years, and weight from (1.5 - 2.5) kg. All geese were euthanized and their coelomic cavity was dissected to determine the placement of the digestive organs, including their relative shapes. The coelomic cavity was dissected from the thoracic intake to the vent orifice. Gross descriptions and measurements of the small intestine were taken, including its length, weight, diameter, relative length, and relative weight according to the morphological investigation. Our results showed that the small intestine is made up of three segments (duodenum, jejunum, and ileum), The duodenum forms a U-shaped tube that occupied the pancreas, jejunum has (5) fluxes. Mickel’s diverticulum appeared as a small bunch separating the jejunum from the illum. Illum was shorter than the rest of the small intestine.
The Impact of Two Types of Mycoplasma gallisepticum Vaccines on Broiler Chicken Respiratory System.
Authors: Saad Muofaq Al-Tamimi  , Abtisam Jawad Ali  , Rawah A. Faraj  
Published: October 2023

This study aimed to evaluate the effect of vaccinating 1-day-old broilerchicks with two commercial vaccines such as live chronic respiratorydisease F strain (CRDF) and killed Mycoplasma gallisepticum (MG)vaccines on the respiratory system. For this purpose, one-day-old broilerchicks (n=120) were randomly divided into four groups; (n=30 birdseach). All groups were treated as followed: G1(CRDF): chicks werevaccinated with live CRDF vaccine (eye drop one drop 0.03ml/dose/10 5 ),G2 (killed MG): chicks were vaccinated with killed MG vaccine injectionwith 0.3ml s.c /3 x10 10 C.F.U/ml), G3: chicks were combined vaccinatedwith killed MG and CRDF live vaccines G4: served as controlunvaccinated group. The vaccination was performed at one day old in G1(CRDF), G2(killed MG), and G3 (killed MG and live CRDF). Thehistopathological changes of the trachea and air sacs were examined andevaluated at 35 days old. The results of histopathological examination ofair sacs in the G1(CRDF) revealed various mild epithelial hyperplasiawith papillary-like growth, subepithelial lymphocytic infiltration, in G2
(killed MG), showed hyperplastic epithelial surfaces with moderatelymphocytic infiltration mainly around congestion capillaries. While G3(killed MG and CRDF) showed focal epithelial hyperplasia (villus-like),and perivascular lymphocytic aggregation in laminar C.T. Whereas G4(control) showed normal structures without any histopathological lesions.In the trachea the histopathological changes in G1(CRDF) showed focallymphocytic aggregation with a follicle-like appearance, another sectionshowed focal epithelial and cilia loss with goblet cell hypertrophy of theadjacent gland. G2 (killed MG) showed partial loss of thin mucosa withmild and desquamation lymphocytic infiltration in lamina propria,G3(killed MG and CRDF) showed diffuse mononuclear cells (MNCs)infiltration in tracheal mucous and submucosa with evidence of cysticdilution of adjacent gland together G4 control tracheal tissue showednormal structure without any lesions. Finally, it was determined thatvaccination with killed MG and live CRDF vaccines caused a moreobvious immune reaction (lymphoproliferative infiltration) in therespiratory system, including the trachea and air sac than the vaccinationwith combined killed and live vaccines, while the live Mycoplasmavaccines individually caused minor damage, particularly in the trachea.
Coagulation Abnormalities in Pediatric Patients with β-Thalassemia, An experience at a Tertiary Care Hospital
Authors: Shabbir Ayesha , Farhan Saima , Ur Rehman Attiq , Mazhar Neelam , Hareem Sidra , Iqbal Iram 
Published: October 2023

Life expectancy in thalassemia has markedly improved due to consistent blood transfer and amenability with iron chelation therapy, therefore this improvement is conditioned with various thromboembolic problems of this prolonged disorder including thromboembolic complaints. Objective: To determine coagulation abnormalities in beta (β) thalassemia major patients who have been multi transfused. Methods: This observational study was conducted at Department of Haematology & Transfusion Medicine, Children hospital & University of Child Health Sciences (CH&UCHS), Lahore, from October 2022 to January 2023. The study included 60 β-thalassemic patient, age less than 16 years whose samples were compared with upper and lower normal value as regards to Prothrombin Time (PT), Active Partial Thromboplastin Time (APTT), Protein S, Protein C, liver enzymes (Alanine Transaminase (ALT), Aspartate Transaminase (AST), Gamma-Glutamyl Transferase (GGT). The data were analyzed using IBM SPSS version 23.0. Results: When values were compared, natural clotting inhibitors (Protein S, Protein C) were remarkably reduced in β-thalassemic paeds patients (p<0.001).PT and APTT were prolonged in thalassemic children (p>0.05 and p<0.05 correspondingly). There was substantial increase in concentrations of ALT and AST in β-thalassemic patients (p < 0.001 and p < 0.001 respectively) due to iron over load by multiple transfusions. Conclusions: Marked changes in coagulation inhibition supporting thrombotic tendency was observed in thalassemic children. There were reduced levels of protein C and protein S, independent of slightly prolonged PT and APTT and elevated levels of ALT, AST with normal GGT in thalassemic children.
Quasi Experimental Study to Ascertain Link of PPI to Bone Profile in Healthy Individuals
Authors: Memon Yasra , Shaikh Imran Ali , Karim Imran 
Published: October 2023

Proton pump inhibitor (PPI) is only acid blocking agent used for treating the disease known as gastroesophageal reflux (non-erosive), erosive esophagitis disease, dyspepsia disease and the peptic ulcer disease because of its efficacy and potency. However, overuse of it is examined an immediate result of absence of determination of need for steady treatment in many outdoor subjects Objective: To evaluate impact of proton pump inhibitor (PPI) on bone biochemistry in young individuals of Hyderabad. Methods: The study contained 227 young individuals of age 20-45 years, it was conducted in Liaquat University Hospital, Hyderabad City and Medicine OPD’s of Jamshoro. The research study is undertaken using Quasi experimental study. The study duration is 6 months starting from 15th March 2020 to 15th September 2020 and sampling technique is non – probability convenience. SPSS 21 software is used to analyze the data. The post stratification chi – square test is performed at the interval of 95% confidence, besides it the P-value is observed ≤ 0.05. Results: There is no effect on serum calcium and vitamin D levels with use of proton pump inhibitor PPI. P-value was observed 0.7 for the serum calcium and the p- value for Serum Vitamin D was 0.1. Conclusions: Hence, the study showed that proton pump inhibitor PPI use for less than 6 months have no effect on bone biochemistry.