bluuebunny/crossref_metadata_2025_split huggingface dataset:
Genome-Wide Identification and Expression Analysis of the SQUAMOSA Promoter-Binding Protein-like (SPL) Transcription Factor Family in Catalpa bungei
Authors: Fan Erqin , Liu Caixia , Wang Zhi , Wang Shanshan , Ma Wenjun , Lu Nan , Liu Yuhang , Fu Pengyue , Wang Rui , Lv Siyu , Qu Guanzheng , Wang Junhui 
Published: December 2023

As a plant-specific transcription factor, the SPL gene family plays a critical role in plant growth and development. Although the SPL gene family has been identified in diverse plant species, there have been no genome-wide identification or systematic study reports on the SPL gene family in Catalpa bungei. In this study, we identified 19 putative SPL gene family members in the C. bungei genome. According to the phylogenetic relationship, they can be divided into eight groups, and the genes in the same group have a similar gene structure and conserved motifs. Synteny analysis showed that fragment duplication played an important role in the expansion of the CbuSPL gene family. At the same time, CbuSPL genes have cis-acting elements and functions related to light response, hormone response, growth and development, and stress response. Tissue-specific expression and developmental period-specific expression analysis showed that CbuSPL may be involved in flowering initiation and development, flowering transition, and leaf development. In addition, the ectopic expression of CbuSPL4 in Arabidopsis confirmed that it can promote early flowering and induce the expression of related flowering genes. These systematic research results will lay a foundation for further study on the functional analysis of SPL genes in C. bungei.
H .S. LEVCHENKO’S MUSIC PEDAGOGY
Authors: Haidamaka V. 
Published: December 2023

This article combines scientific approaches to understanding the pedagogical work of Professor Hryhorii Semenovych Levchenko with his expressive and emotional memories. The relevance of the article is due to the ongoing interest of researchers in the figure of the contemporary educator, including Professor H. Levchenko.
The author emphasizes the role of song in the education of a nationally conscious and self-aware citizen of Ukraine. She convincingly argues that the aspects of the influence of musical art on the formation of the personality of future teachers have always been the foundation of the teaching and choral work of Hryhorii Levchenko. The Ukrainian folk choir “Kalyna,” created by Hryhorii Semenovych in 1979, became the creative laboratory of the professor, as the researcher believes. Therefore, the goal of the article is to clarify the dominant techniques of Professor H. S. Levchenko’s music pedagogy.
The article establishes that the pedagogue-musician Levchenko paid significant attention to repertoire selection, working with the content of song compositions, and setting an example as a means of influencing the student audience in his educational and upbringing activities. The author relies on original documents, including concert programs, for the analysis of Professor Levchenko’s pedagogy.
Patient experiences of an online consultation system: a qualitative study in English primary care post-COVID-19
Authors: Moschogianis Susan , Darley Sarah , Coulson Tessa , Peek Niels , Cheraghi-Sohi Sudeh , Brown Benjamin C 
Published: December 2023

BackgroundOnline consultation systems (OCSs) allow patients to contact their healthcare teams online. Since 2020 they have been rapidly rolled out in primary care following policy initiatives and the COVID-19 pandemic. In-depth research of patients’ experiences using OCSs is lacking.AimExplore patients’ experiences of using an OCS.Design and settingQualitative study in English GP practices using the Patchs OCS (www.Patchs.ai) from March 2020 to July 2022.MethodThematic analysis of 25 patient interviews and 21 467 written comments from 11 851 patients who used the OCS from nine and 240 GP practices, respectively.ResultsPatients cited benefits of using the OCS as speed, flexibility, and efficiency. Nevertheless, some patients desired a return to traditional consultation methods. GP practices often did not clearly advertise the OCS or use it as patients expected, which caused frustration. Patients reported advantages of having a written record of consultations and the opportunity to communicate detailed queries in free text. Views differed on how the OCS influenced clinical safety and discussions of sensitive topics. Patients who struggled to communicate in traditional consultations often preferred using the OCS, and male patients reported being more likely to use it.ConclusionGlobally, this is the largest in-depth study of patient experiences of an OCS. It contributes new knowledge that the patient experience of using OCSs can be influenced by previously unreported patient characteristics and the conditions they consult about. Further, it contributes recommendations on the design and implementation of the OCS in practice.
Otoimmün Özellikler Gösteren İnterstisyel Pnömoninin Klinik Özellikleri: Tek Merkez Deneyimi
Authors: ORUÇOĞLU Nurdan , BALCI Yüksel 
Published: December 2023

Giriş ve Amaç: Otoimmün özellikli interstisyel pnömoni (OÖİP), altta yatan otoimmün bir süreci düşündüren klinik veya serolojik özelliklerin mevcut olduğu; ancak bağ doku hastalıkları için tanımlanmış sınıflandırma kriterlerinin karşılanmadığı, yakın zamanda tanımlanmış bir antitedir. Bu çalışmanın amacı, OÖİP hastalarının klinik, serolojik ve morfolojik özelliklerini belirlemektir.
Gereç ve Yöntemler: Bu çalışma bir retrospektif kohort çalışmasıdır. Çalışmaya 2015-2022 tarihleri arasında XXX üniversitesi Romatoloji bölümünde OÖİP tanısı ile takip edilen 38 hasta dahil edilmiştir.
Bulgular: Çalışmadaki hastaların yaş ortalamaları 58,26 ± 12,31 idi. Çoğunluğu (n=27, %71) kadın hastalar oluşturmaktaydı. Hastalarda en sık tanımlanan klinik özellikler inflamatuar artrit veya 60 dakikadan uzun süren poliartiküler sabah sertliği (n=9, %23,6) ve Raynaud fenomeniydi (n=9, %23,6). En sık tanımlanan serolojik bulgular antinükleer antikor (ANA) pozitifliği (n=27, %71,1), Anti-Ro/SSA antikor pozitifliği (n=6, %15,8), romatoid faktör (RF) (n=5, %13,2) ve Anti-Siklik sitrüline peptid pozitifliği (Anti-CCP) (n=5, %13,2) idi. Ortalama takip süresi 43,21 ± 23,30 ay olup, takip süresince ex olan 10 hastadan yalnızca biri OÖIP ile ilişkilendirilmiştir. Hastaların 31’i (%81,5) immünsüpresiflerle tedavi edilmiş olup, 29’una (%76,3) steroid tedavisi verilmiştir. Steroidlerle birlikte en çok kullanılan immünsüpresif ilaç siklofosfamid (n=9, %23,6) idi. İmmünsupresif ilaçlara yeterli yanıt alınamayan 4 hastaya (%10,5) ise anti-fibrotik verilmiştir. Morfolojik alanda radyolojik paternler içerisinde en sık nonspesifik interstisyel pnömoni (NSİP) paterni gözlenmiştir (n= 15, %39,5).
Sonuç: Tek merkez deneyimini sunan bu çalışmada OÖİP’nin çoğunlukla kadın hastalardan oluştuğu, sıklıkla eklem bulguları ve Raynaud ile prezente olduğu ve görüntülemede en sık NSİP paterni özelliklerini gösterdikleri belirlenmiştir. Oldukça heterojen özellikler gösteren OÖİP’nin klinik ve morfolojik özelliklerinin iyi belirlenmesi, hastalığın erken tanısı ve tedavisi için önemlidir.
ASPEK KELEMBAGAAN TERHADAP PENYELESAIAN PERKARA PERCERAIAN AKIBAT KEKERASAN DALAM RUMAH TANGGA (KDRT) DI PENGADILAN AGAMA ARSO
Authors: Musrifah  
Published: December 2023

Artikel ini membahas tentang hasil penelitian terkait kasus KDRT yang terdapat di Pengadilan Agama Arso yang penyebabnya diantaranya karena kekerasan fisik, ekonomi, kekerasan psikologis, kekerasan seksual, dan kekerasan spiritual. Penelitian ini dilakukan untuk mengetahui penyebab dan penyelesaian perkara KDRT yang mengakibatkan terjadinya perceraian. Penelitian ini dilakukan selama 2 bulan (Juni- Agustus 2022) dengan lokasi penelitian Kabupaten Keerom (Pengadilan Agama Arso). Hasil penelitian menjelaskan bentuk Penyelesaian Perkara Perceraian Akibat KDRT di Pengadilan Agama Arso ialah dengan cara melakukan penasehatan melalui persidangan atau mediasi diluar persidangan dan bila proses perdamaian tidak berhasil mencapai kesepakatan diantara kedua belah pihak, maka dilanjutkan proses pemeriksaan perkara dalam persidangan dengan menggunakan asas personalitas ke-islaman, asas kebebasan, asas wajib mendamaikan, asas sederhana cepat dan biaya ringan, asas persidangan tertutup untuk umum untuk perkara tertentu, dan asas persamaan kedudukan dimuka hukum. Adapun akibat hukum terhadap korban kekerasan dalam rumah tangga di Pengadilan Agama Arso yakni Penggugat boleh menuntut/menggugat haknya pasca perceraian yakni nafkah lampau, nafkah iddah, mut’ah, hak asuh anak, nafkah anak dan harta gono-gini.
Real-World Health Care Outcomes and Costs Among Patients With Juvenile Idiopathic Arthritis in Spain
Authors: Antón Jordi , Moreno Ruzafa Estefania , Lopez Corbeto Mireia , Bou Rosa , Sánchez Manubens Judith , Carriquí Arenas Sonia , Calzada Hernández Joan , Bittermann Violetta , Estepa Guillén Carolina , Mosquera Angarita Juan , Rodríguez Díez Lucía , Iglesias Estíbaliz , Marti Masanet Miguel , Lopez Montesinos Berta , González Fernández Maria I. , de Lossada Alfonso , Peral Carmen , Valderrama Mónica , Llevat Noelia , Montoro Álvarez María , Calvo Penadés Immaculada 
Published: December 2023

Background: Juvenile idiopathic arthritis (JIA) is the most frequent chronic rheumatic disease in children. If inflammation is not adequately treated, joint damage, long-term disability, and active disease during adulthood can occur. Identifying and implementing early and adequate therapy are critical for improving clinical outcomes. The burden of JIA on affected children, their families, and the healthcare system in Spain has not been adequately assessed. The greatest contribution to direct costs is medication, but other expenses contribute to the consumption of resources, negatively impacting healthcare cost and the economic conditions of affected families. Objective: To assess the direct healthcare, indirect resource utilization, and associated cost of moderate-to-severe JIA in children in routine clinical practice in Spain. Methods: Children were enrolled in this 24-month observational, multicentric, cross-sectional, retrospective study (N = 107) if they had been treated with biologic disease-modifying anti-rheumatic drugs (bDMARDs), had participated in a previous study (ITACA), and continued to be followed up at pediatric rheumatology units at 3 tertiary Spanish hospitals. Direct costs included medication, specialist and primary care visits, hospitalizations, emergency visits or consultations, surgeries, physiotherapy, and tests. Indirect costs included hospital travel expenses and loss of caregiver working hours. Unitary costs were obtained from official sources (€, 2020). Results: Overall, children had inactive disease/low disease activity according to JADAS-71 score and very low functional disability as measured by Childhood Health Assessment Questionnaire score. Up to 94.4% of children received treatment, mainly with bDMARDs as monotherapy (84.5%). Among anti-TNFα treatments, adalimumab (47.4%) and etanercept (40.2%) were used in similar proportions. Annual mean (SD) total JIA cost was €7516.40 (€5627.30). Average cost of pharmacological treatment was €3021.80 (€3956.20), mainly due to biologic therapy €2789.00 (€3399.80). Direct annual cost (excluding treatments) was €3654.60 (€3899.00). Indirect JIA cost per family was €747.20 (€1452.80). Conclusion: JIA causes significant costs to the Spanish healthcare system and affected families. Public costs are partly due to the high cost of biologic treatments, which nevertheless remain an effective long-term treatment, maintaining inactive disease/low disease activity state; a very low functional disability score; and a good quality of life.
AS PRINCIPAIS MANIFESTAÇÕES BUCAIS EM PACIENTES DESDENTADOS INTERNADOS NA UTI: UMA REVISÃO DE LITERATURA
Authors: Almeida Pedro Arthur Silva de , Ponte Yohana de Oliveira 
Published: December 2023

A odontologia no âmbito hospitalar tem como finalidade proporcionar ao paciente uma melhora significativa na condição sistêmica e na qualidade de vida, sendo estabelecida como um ato responsável por tratar da higiene bucal. O objetivo deste trabalho é descrever as principais manifestações bucais que influenciam na saúde integral de pacientes desdentados internados na UTI. Trata-se de uma revisão integrativa da literatura. A coleta de dados nas bases de dados PubMed , BVS (Biblioteca Virtual em Saúde Brasil) e Portal da periódicos Capes. Para a busca dos artigos utilizou-se os descritores cadastrados em Ciências da Saúde: “Oral manifestations”, “Oral hygiene” e “Dental Staff, Hospital”, correspondentes em Língua Portuguesa “Manifestações bucais”, “Higiene bucal” e “Equipe Hospitalar de Odontologia”. Como critério de inclusão, foram definidos artigos publicados nos idiomas português e inglês, estudos do tipo revisão de literatura e ensaios clínicos. Os critérios de exclusão estabelecidos foram estudos in vitro, artigos não encontrados na íntegra, artigos relacionados à pacientes dentados. Como resultados foram encontrados apenas 02 (dois) artigos que demonstraram coerência e correlação com o tema proposto, destacam-se as manifestações bucais relacionados aos pacientes com maior tempo de internação foram ressecamento labial, queilite angular, língua despapilada, candidíase e pneumonia e o conhecimento do médico hospitalar referente à higiene e as manifestações bucais de pacientes internados, destacando-se a doença periodontal e cárie dentária como principais manifestações bucais. Portanto, os pacientes desdentados internados no âmbito hospitalar necessitam de uma equipe multiprofissional para promover diagnóstico, prevenção e tratamento, pois as manifestações bucais demonstram cada vez mais que a cavidade oral está relacionada com a saúde integral. A relação entre as principais manifestações bucais e a saúde geral ocorre por meio da entrada de microrganismos na corrente sanguínea, causando diversos tipos de agravos, como infecções ao coração e aumento a resistência à insulina, piorando assim o controle glicêmico em pacientes diabéticos. No entanto, é necessária a realização de mais estudos com alto rigor científico sobre este tema além de envolver a atuação de profissionais capacitados com habilidades e técnicas específicas para atuar na Odontologia Hospitalar. As principais manifestações bucais que influenciam na saúde integral de pacientes desdentados internados na UTI são ressecamento labial, queilite angular, língua despapilada, candidíase e pneumonia.
olhar diferente para a mesma palavra
Authors: Muniz Rosane de Miranda 
Published: December 2023

O presente artigo procura trazer uma compreensão de um caso clínico, à luz da ontologia existencial do filósofo Martin Heidegger (1889-1976) e a sua analítica do Dasein, denominada daseinsanalítica. Pensamento esse, trazido pelo psiquiatra e psicoterapeuta suíço Medard Boss (1903-1990) para embasar sua maneira de abordar o fenômeno patológico em sua clínica. Procuraremos trazer além dos aspectos gerais do caso clínico, o esclarecimento de algumas dimensões da experiência da paciente a partir da perspectiva de Boss, sobre como realiza seu existir e sobre a noção de privação.
KONSEP SEKOLAH DAMAI: HARMONISASI PROFIL PELAJAR PANCASILA DALAM IMPLEMENTASI KURIKULUM MERDEKA BELAJAR
Authors: Istianah Anif , Maftuh Bunyamin , Malihah Elly 
Published: December 2023

Saat ini pendidikan berpusat pada konsep Sekolah Damai yang bertujuan menciptakan lingkungan belajar yang harmonis, inklusif dan damai. Artikel ini menjelaskan pentingnya mengintegrasikan kurikulum terbuka Pancasila, kurikulum dan profil siswa ke dalam konsep Sekolah Damai. Penelitian ini adalah penelitian kajian pustaka. Hasil kajian pustaka mendeskripsikan bahwa untuk menjawab tantangan yang dihadirkan dengan menyelaraskan Kebebasan Belajar, Kurikulum Kebebasan, dan profil pelajar Pancasila, seperti menyeimbangkan praktik kebebasan akademik dengan keberlanjutan dan mengintegrasikan nilai-nilai Pancasila dengan baik. Manfaat yang mungkin diperoleh dari penerapan konsep Sekolah Damai, seperti: menyediakan lingkungan belajar yang inklusif dan inovatif serta mendorong keterlibatan siswa. Memberikan contoh best practice sekolah yang berhasil mengintegrasikan Pembelajaran Bebas, Kurikulum Mandiri dan Profil Pelajar Pancasila dengan tujuan mewujudkan sekolah damai. Metode untuk menulis artikel ini analisis literatur dan penelitian yang relevan untuk lebih memahami topik yang dibahas. Hasil penelitian ini memberikan pemahaman tentang pentingnya hubungan antara konsep Sekolah Damai: Harmonisasi kurikulum dan profil Pelajar Pancasila dalam implementasi kurikulum Borderless Learning mengarah pada upaya menciptakan lingkungan belajar kooperatif yang damai, inklusif, dan lintas batas. Dalam konteks integrasi antar kurikulum, profil Pelajar Pancasila, dan pemahaman konteks global berperan penting dalam membentuk generasi yang memiliki pemahaman yang lebih luas dan adaptif, generasi yang menjaga perdamaian dan keamanan.
معايير اختيار القيادات الإدارية العُليا وعلاقتها بمستوى الأداء الوظيفي دراسة حالة: المؤسسة الوطنية للنفط والشركات التابع لها بنغازي/ ليبيا
Authors: مسعود جميلة عبد النبي محمد , البركاوي ابتسام خليفة 
Published: December 2023

هدفت هذه الدراسة إلى بيان معايير اختيار القيادات الإدارية العليا واختبار طبيعة العلاقة بينها وبين مستوى الأداء الوظيفي في الشركات النفطية بمدينة بنغازي.
حيث تم تناول بعض الدراسات السابقة ذات الصلة بمشكلة الدراسة الحالية والاستفادة منها في بناء أداة الدراسة. وقد ناقشت الدراسة في جانبها النظري أهم المواضيع والمفاهيم ذات الصلة بمشكلة الدراسة الحالية وإلقاء الضوء على موضوع المعايير والاختيار وطبيعة العلاقة بينها وبين مستوى الأداء الوظيفي.
تكون مجتمع الدراسة من جميع الإدارات بالشركات التابعة للمؤسسة الوطنية للنفط في مدينة بنغازي، وتضم هذه الصناعة (14) شركة ليبية منها (10) مملوكة بالكامل للمؤسسة الوطنية للنفط، (4) منها مشاركة وشركات أخرى عقود. ونظراً لوجود عدد من هذه الشركات في مناطق متفرقة من ليبيا مما أدى إلى صعوبة مقابلة المديرين بهذه الشركات للحصول على البيانات اللازمة للدراسة، عليه، اخْتِيرت الشركات العاملة الموجودة في نطاق مدينة بنغازي.
والقياديون هم رؤساء المجالس والأعضاء والمدراء العامون ومدراء الإدارات العاملة بالشركات قيد الدراسة، وقد تم ذلك بالحصر الشامل لهذه القيادات البالغ عددهم (120) مفردة، ولتحليل بيانات الدراسة وتحقيق أهدافها استخدم برنامج الحزم الإحصائية للعلوم الاجتماعية SPSS)).
وفي الختام، قدمت الدراسة العديد من التوصيات والمقترحات في ضوء النتائج التي حُصِلَ عليها. وحيث إن الدراسة قد أُجْرِيت خلال العام 2014م، يتطلع المؤلفون إلى إعادة إجراءها في القريب العاجل ومقارنة النتائج التي سيُحْصَل عليها مع نتائج الدراسة الحالية للتمكن من تقويم مدى التغير في اختيار المعايير المناسبة للاختيار وبالتالي وضع التوصيات المناسبة وفقاً لذلك.
Lineament Mapping of Jabal Arkenu in Southern Libya
Authors: Afkareen Mohammed. M. , Zamot Jamal. A. , Al Alwani Ragab. M. 
Published: December 2023

Remote sensing technology is an important technique in studying perilously and hard-to-reach places for investigating them in the field. Furthermore, it provides fast and accurate data to characterize natural features or physical objects on the ground. Remote sensing data could be used with other approaches to provide a more comprehensive overview of the feature of interest.
Accordingly, in this study, the linear features of Jabal Arkenu, in the Kufrah Basin, south of Libya, were studied remotely. The main source data is a satellite image produced from the Alos Palsar satellite, which has a spatial resolution of 12.5 meters. The lineament features map of Jabal Arkenu was created by analyzing several shadow relief images. The length, density, direction and intersection of the lineaments have been extracted from the lineaments map and compared to provide clear maps for determining the type of faults, structural relationships and the geology in the study area. Additionally, the central part of Jabal Arkenu is dominated by high to very high lineament density, while the greater part of the study area is characterized by medium to low lineament density. The dominant direction of the analyzed lineaments is in the northeast direction, and they are concentrated in the north and south parts. Some linear features exist as a boundary between Nepheline syenite with Cambrian Sandstone and Phonolite with Syenite granite.
Grammatical aspect of semantics of substantive-infinitive phrases
Authors: Сатина Т.В. 
Published: December 2023

В статье описываются формальные, семантические и функцио-нальные свойства субстантивно-инфинитивных словосочетаний. Субстантивно-инфинитивное словосочетание, имеющее в качестве основного значение атрибутивности, проявляет способность к выражению многослойности семантики и семантическим приращениям без изменения внешней структуры, что создает бо́льшую гибкость синтаксической структуры. Доказано, что в высказывании субстантивно-инфинитивное словосочетание может проявлять конденсированную в нем предикативность, являющуюся результатом его синтаксической деривации.
The article describes the formal, semantic and functional properties of substantive-infinitive phrases. The substantive-infinitive phrase, which has attribution as its main meaning, shows the ability to express multilayered semantics and semantic increments without changing the external structure, which creates greater flexibility of the syntactic structure. It is proved that in an utterance a substantive-infinitive phrase can manifest a predicativity condensed in it, which is the result of its syntactic derivation.
THE YIN-YANG DOCTRINE AS THE MENTAL BASIS OF THE CHINESE FOR THE PERCEPTION OF THE THEORY OF TRANSITIVITY OF V.V. BABAYTSEVA
Authors: Милованова М.С. , Го Сяоюй 
Published: December 2023

В статье проводится сопоставительный анализ между древнекитайской философией инь-ян и русской грамматической теорией переходности для того, чтобы выявить мыслительную основу восприятия китайцами, в целом подготовленными для понимания этой теории. Авторы приходят к выводу о том, что, несмотря на различия, мышление инь-ян в менталитете китайцев способствует лучшему восприятию и распространению теории переходности среди китайских русистов.
This article conducts a comparative analysis between the ancient Chinese philosophy of Yin-yang and the Russian grammatical theory of transitivity in order to identify the mental basis of perception by the Chinese, who are generally prepared to perceive this theory. A conclusion is that despite the differences, Yin-yang doctrine in the Chinese mentality contributes to a better perception and dissemination of the theory of transitivity among Chinese Russian scholars.
What is the role of sensitization in carpal tunnel syndrome where pain impacts functional capacity?
Authors: GÜLER Emel , POLAT Musa , SOYKÖK Gülay , YAVUZ MOLLAVELİOĞLU Tuğçe 
Published: December 2023

Aims: Expression of carpal tunnel syndrome (CTS) caused by the entrapped median nerve includes pain, paraesthesia and numbness. Extra median spread of pain can furthermore be seen as a clinical requirement defined by neuro inflammation. Central sensitization (CS) constructs a similar mechanism. This study aims to evaluate sensitization in patients diagnosed with CTS.
Methods: A total number of 152 patients diagnosed with CTS were evaluated, prospectively. Patients data such as gender, age, body mass index (BMI), disease duration, pain severity (NRS), painDETECT questionnaire, Boston CTS symptom severity scale (SSS) and functional status scale (FSS), CS scale, electroneuromyography results have been collected by the author and then the patients are divided into three groups.
Results: Regarding the age, BMI and CS rate, there was no statistical difference between the three patient groups (p>0.05). However, a statistically significant difference was found between these groups in disease duration, day-time and night-time NRS, Boston SSS, FSS, and pain DETECT scores (p0.05). Yet, statistically significant differences were found in a comparison of the patients with and without CS, in disease duration, NRS night scores, and painDETECT scores (p