bluuebunny/crossref_metadata_2025_split huggingface dataset:
Daya Tarik Minat Generasi Z Dalam Bertransaksi Menggunakan Financial Technology (E-Wallet)
Authors: Rahman Alifiyah Nabilah , Purwanto Setiyo 
Published: February 2024

To maximize the use of technology in expediting financial services, financial technology makes transactions in the financial industry easier, more practical, and efficient. Non-cash payment methods, including e-wallets, are highly sought after by consumers. The development of financial technology is common among Indonesians, especially generation Z. Therefore, the population determined in this research case study is the people of DKI Jakarta province who belong to generation Z. The sampling technique in this study was purposive sampling method. The data used used primary data, namely by distributing questionnaires which were responded to by 100 respondents. The analysis technique used in this study using multiple linear regression tests using the SPSS 25 program. The results showed that the variables of effectiveness, trust, and perceived convenience had the same t significance value of 0.000 where the t value was smaller than 0.05. This shows that effectiveness, trust, and perceived ease of use affect the interest in transactions using financial technology (e-wallet) together by 80.4% and the remaining 19.6% is influenced by other factors.
Changes Seen in Platelets and Coagulation Profile in SARS-CoV-2 Infection
Authors: Priyadarshinee Anamika , Lakhey Ashish , Acharya Sneh , Regmi Samikchhya , Bhatta Sushama 
Published: February 2024

Introduction: COVID-19 is a multisystemic disease with profound effects on the hematolymphoid and coagulation system. It is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) belonging to the Corona viridae. The Objective of the study was to evaluate the platelet and coagulation profile in patients with SARS-CoV-2 infection.
Methods: A descriptive (cross-sectional) study, conducted in KIST medical college and teaching hospital (KIST MCTH), as census data, from 1st June 2021 to 30th December 2021
Results: COVID-19 association was seen more in male patients and most of the admitted patients had moderate severity. N:L ratio was higher in 55.6% (n= 29) admitted cases. In the admitted patients of COVID thrombocytopenia was noted in only 10 patients. Forty-two patients had normal platelets. Nine patients had raised Prothrombin time and 21 patients had raised D-dimer.
Conclusion: Unlike most viral infections, COVID-19 showed systemic inflammation and DIC features with lymphopenia and increased D-dimer. Thrombocytopenia is not associated with less severe cases; thus, it cannot be used as a prognostic factor.
Knowledge about Prenatal Exercises among Medical Undergraduates in a Medical College in Nepal
Authors: Maskey Smrity , Thapa Bibechan , Karki Shreyashi , Pandey Aakriti , Tiwari Anu , Pokhrel Story 
Published: February 2024

Introduction: Exercise and regular physical activity during pregnancy are beneficial to maintain good maternal and fetal health, and to improve the ability to cope with labor. Pregnant women can follow physical activity guidelines with pregnancy-specific recommendations unless contraindicated. The benefits of prenatal exercises include reduction in cesarean rates, appropriate maternal and fetal weight gain, and managing gestational diabetes. This study aims to assess knowledge about prenatal exercises among medical undergraduates.
Methods: A cross-sectional study was carried out among 254 medical undergraduates after ensuring ethical clearance (ref no 077/078/48). Simple random sampling was done. Five-point Likert scale questionnaire was directly administrated. Data entry and analysis were done with Statistical Package for the Social Sciences version 26 version. Descriptive analysis were carried out and point estimate at 95% Confidence Interval was calculated along with frequency and percentages for binary data.
Results: Out of 254 undergraduate medical students, 88.58% (225) participants disagreed that pregnant women should rest only while 85.43% (217) agreed that every pregnant women should adapt prenatal exercises. About 93.37% (237) agreed that prenatal exercises are safe. About 76.38% (194%) participants agreed that prenatal exercises make normal delivery easier but only 55.12% (140) agreed that prenatal exercises prevents the aches of having CS. Almost all participants (99.2%) wanted to learn more about prenatal exercises.
Conclusions: The knowledge of medical undergraduates on prenatal exercises was found inadequate when compared to reported literatures. However, the willingness of the participants to learn about it suggests programs and policies be formulated to incorporate prenatal exercises in medical curriculum and training.
Initial Experiences in Starting a Renal Transplant Center: Ab-initio profile of donors we encountered
Authors: Dargay Sonam , Bodapati Shruti , Bodapati Sivaramakrishna 
Published: February 2024

Introduction: Kidney transplantation is the ultimate treatment for people with ESRD. The Donors for such kidney can be either from living or from cadaver donors. The living donors are healthy people who are thoroughly worked up and screened. For the benefit of another person we subject a healthy subject to surgery. For this reason a study on how a donor’s health is affected as a result of kidney donation needs evaluation.
Methods: This study is a combined retrospective and prospective study. The retrospective data were taken from the case sheet of patients maintained at the urology department of a large tertiary level hospital doing renal transplants. Prospective study of the cases were carried out by following up detail donor workup including history, clinical examination and investigations relevant to donor work up as per the protocol followed in the transplant center. Each prospective case were studied for complications of donor nephrectomy and followed up for a period of up to one year after donor nephrectomy.
Results: A total of 36 donors underwent donor nephrectomy during the study period. There were only two laparoscopic nephrectomies and 34 by standard retroperitoneal open surgical method. 13 donors had postoperative complications (36.11%). The duration of stay varied from 5-35 days. Majority of the donors (44%) had a stay within the range of 10-15 days, followed by a stay of 5-10 days (30-56 percent of the donors). The remaining stay ranged from 2.78% to 8.33 %. The average stay in the hospital was found to be 14.17 days with SD of 6.45 days.
Conclusion: Living kidney donation with all its advantages still holds the best solution for end stage renal disease. The inconvenience of haemodialysis along with the cost and loss of labour of a patient on haemodialysis makes renal transplant the ultimate replacement of a non-functioning kidney. The advantage of timing of transplantion according to the condition of the recipient makes it far superior than cadaver grafts.
Pattern of Pre-Anesthetic Medications Used In Various Surgical Specialties in A Tertiary Care Hospital
Authors: Pradhan Rosi , Maharjan Anil , Lamichhane Bibena , Bhochhibhoya Anisha , Laudari Uttam , Khadka Anjan , Bhochhibhoya Ashmita , Bista Parichhya , Kumar Jha Aditya 
Published: February 2024

Introduction: Most of the surgeries done in our country under anesthesia are mostly at urban region and very low number at remote areas. Even those surgeries done under anesthesia do not receive proper premedication. Pre-anesthetic medicine has been linked to a variety of outcomes, including postoperative recovery time, the need for postoperative analgesia, and hospital stay. Yet, we have very less data regarding the patterns of use of drugs for premedication.
Methods: It is a cross-sectional descriptive study performed in the department of Anesthesiology at KIST Medical College and Teaching Hospital from 15th Feb 2022 till 14th Feb 2023, after obtaining ethical clearance from the Institutional Review Committee. The total sample size was 385 which were calculated using Cochrane formula. All the patients who belonged to American Society of Anesthesiologists (ASA) I-III undergoing elective surgical procedures and administered premedication were selected for the study only after their informed written consent.
Results: Out of 496 cases, 385 (53.8%) of patients were selected and pre-medications were recorded. The premedication used were metoclopramide 375 (97.4%), pantoprazole 375 (97.4%), paracetamol 52 (13.5%), glycopyrrolate 26 (6.75%), pregabalin 21 (5.45%), alprazolam 20 (5.19%), and lorazepam 1 (0.25%). Types of surgeries categorizations were 59.22 % general surgery, 17.92 % Gynecological and Obstetrics, 17.14 % Orthopedic cases, 4.67 % ENT and 1.04 % dental cases.
Conclusion: The most commonly administered pre-anesthetic drugs were metoclopramide, pantoprazole, paracetamol, pregabalin, alprazolam and then lorazepam.
Epidemiological and Clinical Profiles of Cases of Appendicitis Managed At a Tertiary Hospital in Nepal
Authors: Shakya Yagya Ratna 
Published: February 2024

ABSTRACT
Introduction: Appendicitis is worldwide the most common surgical emergency that affects both genders and all ages.
Methods: This study aimed to assess the epidemiology and clinical profiles of cases of appendicitis in Nepal and compare it with the existing literature. A cross-sectional descriptive study was done on 756 patients attending Dhulikhel hospital a tertiary health care center in Dhulikhel Nepal. All the patients clinically diagnosed with appendicitis were included in this study. The required information was coded, and entered in a Microsoft Excel spreadsheet and analysis was done using SPSS version 22. The epidemiological and clinical findings were analyzed.
Results: Mean age of patients was 29.13 ± 16 years. Out of 756 patients, 458 (60.9 %) of patients were male and 298 (39.4%) were females. The majority 42.7% of patients were from Brahmin/Chhetri ethnicity. The most common procedure for the management of appendicitis was laparoscopic appendectomy (61.24%) followed by Open appendectomy (30.6%). The mean duration of postoperative hospital stay was highest among conservative (5.2 days) and lowest among laparoscopic appendectomies (2.2 days). Most of the cases were acute inflammation (47.8%).
Conclusion: Appendicitis is more common among males than females, and between 20- 30 yrs of age. The most common surgical procedure was laparoscopic appendectomy, and it has been recorded those minimum days of postoperative hospital stay was also found among laparoscopic appendectomy. Most cases are acute inflammation.
Attitudes of Undergraduate Medical Students towards Personal and Professional Advancement (PPA): A Cross- sectional Study at School of Medicine, Maldives National University
Authors: Kumar Yadav Shekhar , Shakya Shuvechha , Ranabhat Pashupati , Zubair Shaistha 
Published: February 2024

Introduction: Personal and Professional Advancement module (PPA) is introduced in today’s updated medical school curriculum. The main purpose of PPA is to assess student’s personal growth and professional development. It emphasizes the importance of “hidden curriculum” as part of medical training. The success story of a modern-day physician center is substantially based on the knowledge of proper professional skills. PPA is introduced to achieve the general objective of producing medical doctors who are caring, holistic and professional in their approach. Therefore, it has become extremely important to start a professional skills course early on in undergraduate medical study, but to date, this has been given relatively little or no emphasis. In the present study, an attempt was made to assess the attitude of undergraduate medical students towards learning the PPD module
Methods: A total of 130 undergraduate medical students at School of Medicine were included in the study. This study was based on an anonymous self-administered questionnaire on attitudes of undergraduate medical students towards personal and professional advancement module. The data were collected from all the batches of students. All participants (n=130) had completed the questionnaires completely, therefore, 100% of samples were included for data analysis. Data was coded and entered into Microsoft Excel software and analyzed using SPSS version 22.0
Results: The content that was covered by the PPA sessions satisfied the needs of the 46.2% of students, 44.6% were not sure and 9.2% were not satisfied. The students seem to embrace the course better as they go into clinical practice.
Conclusion: This study provides perceptions of undergraduate medical students towards PPA module learning. We suggest the integration of PPA module curriculum into the undergraduate medical syllabus, with an acceptable, focused, and interesting teaching module.
Spectrum of Intracerebral Hemorrhage in a Tertiary Hospital
Authors: Prajapati Chandra Man , Sah Lalit Kumar , Koirala Sachit , Shrestha Sikhar , Dhakal Grish , Adhikari Eliza , Mukhia Rupashi , Koirala Kamal , Rai Arati 
Published: February 2024

Introduction: Intracerebral hemorrhage is a devastating type of stroke that leads to profound morbidity and carries high mortality. Survivors of hemorrhagic stroke suffer not only from physical and social decline but also results in loss of productivity and financial burden.
Causes of hemorrhagic stroke are hypertension, coagulopathic condition, diabetes mellitus and cardiovascular diseases. lesional hemorrhagic stroke can be due to subarachnoid hemorrhage from intracranial aneurysm, arteriovenous malformation, dural arteriovenous fistula etc.
Methods: A retrospective cross sectional study carried out at KISTMCTH. Data from six years duration was analysed from hospital records, outpatient department records. Patients that presented with intracranial hemorrhage were included. Post operative patients and traumatic intracerebral hemorrhage cases were not included.

Results: Total of 112 patients was included in the study. 73 (65.1%) of them were male and 39 (34.8%) were female. putamen and caudate region were most common 47 (41.9%) followed by subarachnoid region 27 (24.1%), thalamus 19 (16.9%), cerebellum 9 (8.04%) , lobar region 8 (7.1%) and brainstem 2 (1.7%). Intracranial hemorrhage was more common in age group of 41-60 years 59 (52.6%) followed by age group 61- 100 years 42 (37.5%). 14 (51.8%) female had subarachnoid hemorrage in comparision to 13 male (48.1%). Anterior communicating artery aneurysm had highest occurrence 10 (37%) followed by middle cerebral artery aneurysm 6 (22.2%) , paraclinnoidal / anterior choroidal/posterior communicating artery aneurysm 5 (18.5%), vertebral artery aneurysm 3 (11.1%), distal anterior cerebral artery aneurysm 1 (3.7%).
Intracranial hemorrhage had highest occurrence on the month of January (15%) and lowest on the month of November (3.57%). 29 (25.8%) of total intracranial hemorrhage patient had intraventricular extension of hemorrhage. Intraventricular extension was more common in thalamic hematoma 15 (13.39%) followed by caudate/putaminal hematoma 10 (8.9%), cerebellum 3 (2.6%).Modified Rankin Scale ( MRS) outcome score was found to be highest as MRS 6 for 34 (30.6%) patients . while good outcome in terms of MRS 1 , MRS 2 and MRS 3 were observed for 7 (6.2%), 26 (23.2%), 25 (22.3%) patients respectively.
Conclusion: Hypertension remains one of the major risk factor that results in various location specific hemorrhage and it shows specific peak seasonal variation. Proper blood pressure control is recommended for prevention of intracranial hemorrhages.
THE SYSTEMATIC REVIEW OF EXAMINING THE CONNECTION BETWEEN NUTRITION AND VERTIGO
Authors: Fitri Bumantari Annisa , Ade Dewi Fitri 
Published: February 2024

Aim : This study examined the association and connections between the uptake of nutrition and vertigo
Methods: By comparing itself to the standards set by the Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) 2020, this study was able to show that it met all of the requirements. So, the experts were able to make sure that the study was as uptodate as it was possible to be. For this search approach, publications that came out between 2014 and 2024 were taken into account. Several different online reference sources, like Pubmed and Science Direct, were used to do this. It was decided not to take into account review pieces, works that had already been published, or works that were only half done.
Result: In the PubMed database, the results of our search brought up 93 articles, whereas the results of our search on Science Direct brought up 163 articles. The results of the search conducted for the last year of 2014 yielded a total 67 articles for PubMed and 12 articles for Science Direct. In the end, we compiled a total of 4 papers, 2 of which came from PubMed and 2 of which came from Science Direct. We included four research that met the criteria.
Conclusion: In summary, nutrient intake and consumption frequency of certain food categories varied significantly.
ASSOCIATION OF SMOKING AND BLADDER CANCER: AN UPDATED SYSTEMATIC REVIEW
Authors: Amal Ramadhani Rizkia , Fithri Rofifa Amira 
Published: February 2024

Introduction: Bladder cancer is the 10th most common global cancer, with increasing incidence, primarily linked to smoking, occupational exposures, and genetic factors. This systematic review explores the association between tobacco use and bladder cancer, emphasizing the importance of understanding its multifactorial etiology for effective prevention.
Method: The researchers in this study followed the 2020 Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines to ensure that their work met the required standards. This was done to ensure the precision and reliability of the conclusions derived from the research.
Result: Our search produced 18 results. After looking at the titles and summaries, we found several papers that fit our criteria. At first, we excluded few articles because they were written in review and case report style. But after reading the full papers carefully, we included five papers in our final analysis. These papers included two-sample univariable and multivariable Mendelian Randomization (MR) analysis, case control study, prospective cohort study of patients with NMIBC diagnosed from 2015 to 2019, experimental study, and rtrospective study.
Conclusion: The systematic review involved Mendelian Randomization analysis, underscores smoking as a significant risk factor for bladder cancer, with no evidence linking alcohol consumption to the disease. In a prospective cohort study on Non-Muscle Invasive Bladder Cancer, the study establishes a dose-dependent relationship, emphasizing the urgency for effective smoking cessation interventions in patients, especially those with prolonged smoking history. Additionally, the investigation into molecular pathways reveals the upregulation of the platelet-activating factor (PAF) pathway by cigarette smoke exposure, suggesting PAF-PAF receptor (PAF-R) interaction as a promising therapeutic target for managing bladder cancer growth.
MOŽNOSTI REHABILITÁCIE PACIENTA PO RANIOCEREBRÁLNOM PORANENÍ V NRC. KOVÁČOVÁ
Authors: Šinská Marketa 
Published: February 2024

Východisko: V atestačnej práci sa v teoretickej časti venujeme problematike kraniocerebrálnych poranení a ich rehabilitačnej liečbe v NRC Kováčová. V praktickej časti sa zameriavame na zhodnotenie efektu komplexnej rehabilitácie pomocou testovania funkčného stavu pacientov.
Cieľ: Cieľom práce bolo vyhodnotiť efektívnosť komplexnej rehabilitačnej liečby pacientov s traumatickým mozgovým poškodením testovaním funkčných schopností pomocou FIM testu na začiatku a po ukončení liečby v NRC Kováčová. Súbor: Súbor pacientov bol reprezentovaný 12 pacientami oboch pohlaví vo veku od 20 do 59 rokov. Maximálny čas od úrazu bol 12 mesiacov, minimálny 2 mesiace. Dĺžka pobytu bola od 7 týždňov do 3 mesiacov.
Metóda: Na hodnotenie funkčnej zdatnosti pacientov na začiatku komplexnej rehabilitačnej liečby a po jej ukončení sme použili test FIM – Functional Independent Measure.
Výsledky: Celkové FIM skóre bolo pri príjme v priemere 59 pri prepustení v priemere 96. Výsledky sme štatisticky spracovali pomocou párového t-testu. Štatistické testovanie preukázalo signifikantne zvýšenie celkového FIM skóre po absolvovaní komplexného rehabilitačného pobytu v NRC Kováčová. Celkový výsledok rehabilitačnej liečby u pacientov po TMP možno hodnotiť na základe t- testu ako signifikantne zlepšený, čo zodpovedá výsledkom rehabilitačných pracovísk vo svete. Záver: Vďaka skorej ústavnej RHB liečbe sa dosiahlo zlepšenie funkčného stavu, avšak treba si uvedomiť, že veľakrát pretrváva určitý stupeň disability. Preto je potrebné pokračovať v rehabilitačnej starostlivosti ambulantnou formou (rehabilitácia, psychológ, logopéd apod.).
PÁDY U OSOB S ROZTROUŠENOU SKLERÓZOU
Authors: Menkyová I , Andělová M , Novotná K 
Published: February 2024

Porušená posturální stabilita zapříčiňuje u osob s RS i zvýšené riziko pádů. Uvádí se, že více než 50 % osob s RS má s pády zkušenost. Nepříjemný zážitek pádu často způsobuje strach z dalších pádů, což může vést k bludnému kruhu, ve kterém pacienti omezují své fyzické, sociální a další aktivity. Cílem naší studie bylo zjistit, které klinické charakteristiky korelují s výskytem pádů a obav z pádů u pacientů s RS v českém prostředí.
Ze souboru 69 osob s RS, které byly zařazeny do naší studie, bylo na základě pádů v anamnéze identifikováno celkem 13 osob (18,8 %) s opakovanými pády v anamnéze. Obavy z pádů vyjádřené skórem v dotazníku FESI výrazně korelovaly s mírou neurologické disability (r=0.776) a zvýšenou únavou (r=0.716). Slabší korelace byla nalezena s pomalejší rychlostí chůze (r=0.694) a depresí (r=0.589). Terapeutické intervence cílené k ovlivnění chůze a poruch rovnováhy by tedy měly zohledňovat také zmíněné faktory spojené s výskytem pádů.
VPLYV KOMBINOVANÉHO TRÉNINGU NA MOTORICKÉ FUNKCIE, BALANČNÉ SCHOPNOSTI/ROVNOVÁHU, RÝCHLOSŤ CHÔDZE A KVALITU ŽIVOTA U PACIENTOV S ROZTRÚSENOU SKLERÓZOU
Authors: Klobucká S , Maťašková E , Suchá B , Šiarnik P , Kollár B 
Published: February 2024

Východisko: Cieľom klinickej prospektívnej štúdie bolo posúdiť vplyv kombinovaného tréningu na motorické funkcie, balančné schopnosti/rovnováhu, rýchlosť chôdze a kvalitu života u pacientov s roztrúsenou sklerózou (RS) a zároveň preskúmať vzájomné vzťahy medzi hodnotenými modalitami.
Súbor a metódy: 22 pacientov (18 žien, 4 muži) s relaps-remitujúcou formou RS (RR RS) vo veku 24-66 rokov, s ľahším klinickým postihnutím (Expanded Disability Status Scale (EDSS) ≤ 4), absolvovalo 24 terapeutických jednotiek (T.J.) kombinovaného tréningu počas 8 týždňov s frekvenciou 3x týždenne. Motorické funkcie a rovnováhu sme hodnotili prostredníctvom testu POMA (Performance-Oriented Mobility Assessment) a BBS (Berg Balance Scale), rýchlosť chôdze prostredníctvom 10 metrového testu chôdze (10 mWT) a kvalitu života pomocou WHOQOL-BREF.
Výsledky: Po 8 týždňovej intervencii sme v sledovanom súbore pacientov zaznamenali štatisticky vysoko signifikantné zlepšenie sledovaných parametrov (p<0,001). Analýzou závislosti zmien priemerných hodnôt POMA a WHOQOL sme v našom súbore nepreukázali štatisticky signifikantnú koreláciu medzi zlepšením motorických funkcií a rovnováhy hodnotených pomocou POMA testu a zlepšením kvality života pacientov.
Záver: Výsledky tejto štúdie dokumentujú pozitívny vplyv kombinovaného tréningu na zlepšenie motorických funkcií, balančných schopností/rovnováhy a rýchlosti chôdze u pacientov s RR RS. Ukazuje sa však, že krátkodobý rehabilitačný program neovplyvní subjektívne vnímanie kvality života u pacientov s RR RS s miernejším zneschopnením (priemerná hodnota EDSS u pacientov bola 2,8 ± 0,88).