bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lurasidone uses and dosages in Spain: RETROLUR, a real-world retrospective analysis using artificial intelligence
Authors: Mora Fernando , Gómez Sánchez-Lafuente Carlos , De Iceta Mariano , Roset Carolina , Cárdenas Antonio , Pérez Daniel , Álvarez-Barón Elena , Gabarda-Inat Irene ,   Savana Research Group
Published: February 2025

IntroductionLurasidone is used for schizophrenia and bipolar depression in many countries, yet there is a lack of existing literature about its use, efficacy, and safety in real life. We aimed to characterize lurasidone-treated patients by analyzing unstructured information in electronic health records (EHRs).MethodsThis was a multicenter, retrospective, observational, and descriptive study that used data extracted from EHRs of patients initiating treatment with lurasidone in four Spanish hospitals from September 2019 to March 2022. Stratification included primary diagnosis, antipsychotic therapy, and lurasidone dose. Natural language processing and machine learning were used to extract and analyze unstructured clinical data using SNOMED CT terminology. Sociodemographic, clinical, and treatment characteristics, as well as symptoms and potential adverse events as efficacy and safety outcomes, were evaluated at inclusion and during follow-up.ResultsAmong 2,374,218 patients attending the participating hospitals during the study period with 66,523,391 EHRs, 272 initiated lurasidone and were included. Median (Q1; Q3) age was 46 (37; 56) years, and 60.3% were female. Common comorbidities were hypertension (46.7%), dyslipidemia (44.5%), and diabetes (30.5%), and 87.1% had received a median of three antipsychotics before lurasidone, being olanzapine (52.9%) and quetiapine (45.2%) the most frequently used. During follow-up, 16.9% of the patients discontinued lurasidone, and few patients (&lt;1.2%) reached high doses (111 and 148 mg/day). Lurasidone demonstrated effectiveness in reducing positive and negative symptoms, anxiety, depression, and suicidal ideation, with a marked reduction in most of the adverse events compared to the pre-lurasidone period.DiscussionLurasidone reduced positive and negative symptoms frequencies with a favorable safety profile, while low discontinuation rates suggest efficacy-tolerability balance, patient satisfaction, and acceptability. Our data reflect that in Spain lurasidone is used at low doses, limiting its beneficial effects according to clinical trials results.
The effects of profit-sharing distributions on employee stock purchase plan participation
Authors: Hennig Jan C. , Hullmann Rieke , Rau Holger A. , Wolff Michael 
Published: February 2025

IntroductionFirms use various forms of equity-based compensation to allow employees to participate in their success.MethodsWe examine how an unannounced profit-sharing distribution (PSD) affects participation in Employee stock purchase plans (ESPPs), which offer discounted shares. Using panel data from a multinational firm, we find counterbalancing effects of the PSD.ResultsWhile it attracts new participants to the ESPP, a similar share of former participants exit the program after receiving the distribution. This latter effect is particularly pronounced in countries characterized by higher average levels of prosociality.DiscussionOur findings suggest that unexpected profit sharing can have heterogeneous effects on ESPP participation across different cultural contexts.
Determinant of unmet need for family planning among adolescent and young women in Kenya: multilevel analysis using recent Kenyan demographic health survey
Authors: Damtew Beyene Sisay , Abdi Hinsermu Bayu , Hussien Beker Ahemed , Tiruye Getahun , Urgie Nafyad Tolossa , Yigezu Beniam worku , Mohammed Sifan Ahmed , Fente Bezawit Melak 
Published: February 2025

BackgroundUnmet need for family planning (FP) refers to the proportion of women who are fecund, sexually active, and wish to delay or limit childbearing but are not using any effective contraceptive method. Unmet need for FP remains a significant public health concern, particularly among young women aged 15–24 years. This study explores the determinants of unmet need for FP among young women.Method and materialThis study used data from the 2022 Kenyan Demography and Health Survey to investigate the relationship between various factors and a binary outcome variable of unmet need for family planning among adolescent young age group. A multilevel binary logistic regression model was used to analyze the data, accounting for the clustering effects of the survey data. The statistical significance of the relationships was assessed using adjusted odds ratios with 95% confidence intervals. The model with the lowest deviance was considered the best fit for the data.ResultMagnitude of unmet need family planning among adolescent young age in Kenya is 25% (95% CI: 24.5%–26%). Determinants of Unmet need for family planning are age 15–19 (AOR: 3.4, 95%CI (1.3–11), undecided desire number of children (AOR: 2.3, 95%CI: 1.4–2.1), age at first sex 15–29 (AOR: 2.7, 95%CI: 1.2–6.2), rural residency (AOR: 3.9, 95%CI: 1.1–14), high community level poverty (AOR: 2.1, 95%CI: 1.1–4.5).ConclusionThe study finds that 25% of young women in Kenya lack access to family planning. Factors like age, desired family size, early sex, rural life, and poverty contribute to this. These factors create barriers that hinder women's ability to plan their pregnancies and access necessary resources. Younger women, those in rural areas, and those living in poverty are particularly affected. Addressing this issue requires a comprehensive approach that considers the specific circumstances of these vulnerable populations.
Control Error Convergence Using Lyapunov Direct Method Approach for Mixed Fractional Order Model Reference Adaptive Control
Authors: Ceballos Benavides Gustavo E. , Duarte-Mermoud Manuel A. , Martell Lisbel Bárzaga 
Published: February 2025

This paper extends Lyapunov stability theory to mixed fractional order direct model reference adaptive control (FO-DMRAC), where the adaptive control parameter is of fractional order, and the control error model is of integer order. The proposed approach can also be applied to other types of model reference adaptive controllers (MRACs), provided the form of the control error dynamics and the fractional order adaptive control law are similar. This paper demonstrates that the control error will converge to zero, even if the derivative of the classical Lyapunov function V˙ is positive during a transient period, as long as V˙(e,ϕ) tends to zero as time approaches infinity. Finally, this paper provides application examples that illustrate both the convergence of the control error to zero and the behavior of V˙(e,ϕ).
Антикризисное управление и дальнейшее его совершенствование
Authors: Стеблянский Л.Н. 
Published: February 2025

Актуальность рассматриваемого вопроса злободневна особенно в настоящее время, когда промышленное производство и катастрофические природные явления создают человеку комплексную угрозу этими компонентами. В статье рассмотрено развитие антикризисного управления и предложен вариант развития ее элементов через дальнейшее совершенствование органов управления РСЧС и развитие системы оперативного принятия решения посредством развития интеллектуальных систем (базы данных), в том числе с использование ортофотопланов
The relevance of the issue under consideration is topical especially at the present time, when industrial production and catastrophic natural phenomena pose a complex threat to humans with these components. The article considers the development of anti-crisis management and suggests a variant for the development of its elements through further improvement of the management bodies of the Emergency management system and the development of an operational decision-making system through the development of intelligent systems (databases), including the use of orthophotoplanes
Sericin-Au nanoparticles composite-based artificial synapse for brain-inspired neuromorphic computing
Authors: Gao Zexin , Zhao Lulu , Ge Mingjia , Zhai Dashuai , Wang Yanqing , Guo Jiajun , Xiao Xia 
Published: February 2025

Abstract
Developing appropriate materials for memristor-based artificial synapses is necessary for advancing brain-inspired neuromorphic computing. Using biomaterials as the resistive switching layer offers promise due to their biocompatibility and biodegradability. This study presents a memristor fabricated using a sericin-Au nanoparticles (NPs) composite. While pure sericin-based devices exhibit digital-type switching, the incorporation of Au NPs enables analog-type resistive switching by controlling the compliance current. This behavior effectively emulates various synaptic functions. Additionally, a simulated artificial neural network utilizing the bio-memristor achieved a learning accuracy of 92.8% in handwritten digit recognition. These findings highlight the potential of the sericin-Au NPs composite for neuromorphic applications.
Systematic investigation of charge transport and thermoelectric properties in semicrystalline polymers: electrochemical doping effects on doping level and temperature dependence using one sample
Authors: Ito Shun-Ichiro , Tanaka Hisaaki , Oshima Yugo , Kanahashi Kaito , Ito Hiroshi , Chen Binjie , Ohta Hiromichi , Takenobu Taishi 
Published: February 2025

Abstract
We developed a system to measure the temperature dependence of the Seebeck coefficient (S), electrical conductivity, and magnetoconductivity of conducting polymers with controlled doping levels, using an electrolyte-gated transistor structure on a single sample. In the semicrystalline polymer poly[2,5-bis(3-alkylthiophen-2-yl)thieno[3,2-b]thiophene] (PBTTT), S reflects hopping-like transport in the low-doped state, while metallic behavior dominates in the highly-doped state. At low temperatures in the highly-doped regime, S deviates from metallic behavior, showing an unusual trend attributed to the coexistence of localized and delocalized transport processes. Magnetoconductance measurements down to 80 mK confirm this coexistence, highlighting the interplay between two-dimensional weak localization and variable-range hopping. These findings reveal the complexity of transport mechanisms in conducting polymers and provide essential insights for optimizing thermoelectric and electronic devices through careful control of doping and transport properties.
PENGARUH KOMITMEN ORGANISASI, KUALITAS SUMBER DAYA MANUSIA (SDM) DAN PEMANFAATAN TEKNOLOGI INFORMASI TERHADAP IMPLEMENTASI STANDAR AKUNTANSI PEMERINTAH (SAP) BERBASIS AKRUAL PADA PEMERINTAH DAERAH KABUPATEN KUANTAN SINGINGI
Authors: Candra Diki , Diskhamarzaweny Diskhamarzaweny , Dewi Dessy Kumala 
Published: February 2025

Abstract
This aims of this research are to know the effect of organizational commitment, quality of human resources and Utilization of Information Technology on the implementation of accrual-based government accounting standards in the regional government of Kuantan Singingi. The population in this study are employees of the regional apparatus organization Kuantan Singingi who work in the financial department which consists of the Head of Finance, Treasurer of Expenditures, Treasurer of Receipts and financial staff. Data were analyzed using multiple linear regression with a statistical program (SPSS 25), after the classical assumption test was fulfilled. The result of the research shows that Organizational Commitment, Quality of Human Resources and Utilization of Information Technology simultaneously had a positive and significant effect on the implementation of accrual-based government accounting standards in the regional government of Kuantan Singingi Regency.

Keywords : Organizational Commitment, Quality of Human Resources, Utilization of Information Technology, Implementation of Accrual Based Government Accounting Standards.
Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh komitmen organisasi, kualitas sumber daya manusia dan pemanfaatan teknologi informasi terhadap implementasi standar akuntansi pemerintah (SAP) berbasis akrual pada pemerintah daerah Kabupaten Kuantan Singingi. Populasi dalam penelitian ini adalah pegawai pada organisasi perangkat daerah Kabupaten Kuantan Singingi yang bekerja di bagian keuangan yang terdiri dari Kepala Sub Bagian (Kasubbag) Keuangan, Bendahara Pengeluaran, Bendahara Penerimaan dan staff keuangan. Data dianalisis dengan menggunakan regresi linier berganda dengan alat program statistik (SPSS 25), setelah uji asumsi klasik terpenuhi. Hasil penelitian ini menunjukkan bahwa Komitmen Organisasi, Kualitas SDM dan Pemanfaatan Teknologi Informasi secara simultan berpengaruh signifikan terhadap implementasi SAP berbasis akrual pada pemerintah daerah Kabupaten Kuantan Singingi

Kata Kunci : Komitmen Organisasi, Kualitas Sumber Daya Manusia (SDM), Pemanfaatan Teknologi Informasi, Implementasi Standar Akuntansi Pemerintah (SAP) Berbasis Akrual
Pengaruh Rasio Keuangan Terhadap Perubahan Laba Pada Perusahaan Sektor Bahan Baku di Bursa Efek Indonesia
Authors: Roza Ela Alvina , Irwan Muhammad , Sapridawati Yeni 
Published: February 2025

Penelitian ini menganalisis pengaruh rasio keuangan terhadap perubahan laba perusahaan sektor bahan baku yang terdaftar di Bursa Efek Indonesia (BEI) selama periode 2020-2022. Fokus utama adalah pada rasio keuangan seperti Current Ratio, Debt to Equity Ratio, Total Assets Turnover, dan Net Profit Margin. Metode yang digunakan adalah analisis regresi linear berganda dengan data panel yang bersumber dari laporan keuangan perusahaan. Hasil penelitian menunjukkan bahwa Current Ratio dan Net Profit Margin memiliki pengaruh positif yang signifikan terhadap perubahan laba, sedangkan Debt to Equity Ratio dan Total Assets Turnover tidak menunjukkan pengaruh yang signifikan. Temuan ini memberikan wawasan penting bagi manajemen perusahaan dan investor dalam memahami faktor-faktor yang mempengaruhi kinerja laba di sektor bahan baku, yang memainkan peran penting dalam perekonomian Indonesia.
Pierwszy Sojusznik, czyli Trzeci Człowiek. Historia i inni
Authors: Uherek Paweł 
Published: February 2025

Każdy zapis, w tym również o charakterze historycznym, staje się narracją, a każda narracja musi skorzystać z tropu, czyli „tonacji”, „sposobu” prezentacji opowieści. Gra wideo nie odtwarza więc historii przez przywołanie obrazów przeszłości, lecz przez wybór charakterystycznego tropu. Jedną z głównych cech tropu gry jest postać bohatera, który przywołuje cechy herosów kultury oralnej: odwagę, męstwo, poświęcenie. Taki bohater może stanąć w sytuacji tragicznej. Tragizm łączy się z doznaniami immersyjnymi i doświadczeniem „bycia-w-świecie”. Dzięki tak opowiedzianej historii powraca przesłanie etyczne, powraca pierwotny związek czynu i odpowiedzialności. W ten sposób może zostać dopowiedziany, uzupełniony, dyskurs historiograficzny. Kwestie te zostają omówione na przykładzie gry Velvet Assassin – opowieści o działaniach dywersyjnych w okresie II wojny światowej na terenach okupowanych przez hitlerowców.
Pelatihan Bagi Operator Bengkel Di Surabaya Barat Dampak Emisi Dari Penggunaan Bahan Aditif Butanol-Etanol Dengan RON-90 Pada Kendaraan Bermotor
Authors: Kholili Navik , Setyono Gatot , Nugroho Alfi , Khusna Dwi 
Published: February 2025

Bahan bakar bioalkohol memiliki beberapa keunggulan signifikan dibandingkan bahan bakar alternatif lainnya, termasuk kemampuan untuk bekerja pada mesin yang sudah ada serta kemampuan untuk mengurangi emisi gas rumah kaca. Kegiatan ini bertujuan intuk menentukan seberapa jauh tingkat emisi yang dihasilkan mesin SI dengan menggunakan bahan bakar butanol-etanol-RON-90. Sifat bahan bakar butanol-etanol menyajikan sifat-sifat terpenting yang memungkinkan bahan bakar tersebut sebagai kandidat yang cocok sebagai bahan bakar alternatif untuk mesin SI. Emisi mesin seperti NOx, CO dan HC telah dievaluasi terkait karakteristik pada bahan bakar bensin. Kegiatan pelatihan ini dilaksanakan pada bengkel AHASS di sambikerep Surabaya Barat, peserta yang mengikuti dari para operator dan teknisi bengkel tersebut. Alat uji yang digunakan adalah exhaust analyzer gas Qrotech QROI-401 menunjukkan bahwa bahan bakar butanol-etanol-RON-90 memberikan hasil yang berbeda terhadap emisi mesin. fenomena tersebut menunjukkan hasil yang optimal untuk butanol-etanol dibandingkan dengan bahan bakar bensin RON-90. Sehingga kegiatan pelatihan ini dapat disimpulkan bahwa butanol-etanol mampu mengurangi emisi gas buang mesin yang berbahaya, namun dengan mengorbankan karakteristik kinerja mesin yang lebih rendah.
On the Observational Solid Angle in Estimating the Moon-based Disk-integrated Earth Outgoing Longwave Radiation
Authors: Ye Hanlin , Guo Huadong , Liang Dong , Xu Zhen , Jin Yin , Liu Guang 
Published: February 2025

Abstract
Equipping sensors on the lunar surface would enable the capture of Earth’s outgoing longwave radiation (OLR) from nearly an entire hemisphere. However, the Earth’s nonsphericity would profoundly impact the observational solid angle, thereby influencing the disk-integrated Earth OLR estimation. This study analyzes the impact of the Earth’s ellipsoidal shape on the OLR estimation by examining the effects of the observational solid angle. In particular, an expansion-series-based method is proposed for calculating the observational solid angle, avoiding complex numerical integration. Three critical issues are analyzed. (1) Comparing the observational solid angles calculated by using an Earth ellipsoidal model versus those obtained by adjusting the Earth’s radius. We find that adjusting the Earth’s radius can approximate the results based on an Earth ellipsoidal model, offering insights into parameterizing the observational solid angle. (2) Parameterizing the observational solid angle through series expansion, which is validated by comparing the associated results to those from numerical integrations. The observational solid angle is parameterized into two components: one is attributable to a variable Earth radius and another is related to the nadir point’s latitude and the Earth–Moon distance. (3) Guiding parameter selection for observational solid angle estimation. These findings enhance our understanding of disk-integrated Earth OLR estimates and provide a unique tool for establishing benchmarks for the Earth samples needed in the study of habitable planets, thereby contributing to sustainable development.
Observations of Microlensed Images with Dual-field Interferometry: On-sky Demonstration and Prospects
Authors: Mróz Przemek , Dong Subo , Mérand Antoine , Shangguan Jinyi , Woillez Julien , Gould Andrew , Udalski Andrzej , Eisenhauer Frank , Ryu Yoon-Hyun , Wu Zexuan , Liu Zhuokai , Yang Hongjing ,   —, Bourdarot Guillaume , Defrère Denis , Drescher Antonia , Fabricius Maximilian , Garcia Paulo , Genzel Reinhard , Gillessen Stefan , Hönig Sebastian F. , Kreidberg Laura , Bouquin Jean-Baptiste Le , Lutz Dieter , Millour Florentin , Ott Thomas , Paumard Thibaut , Sauter Jonas , Shimizu T. Taro , Straubmeier Christian , Subroweit Matthias , Widmann Felix ,   (The GRAVITY+ Collaboration), Szymański Michał K. , Soszyński Igor , Pietrukowicz Paweł , Kozłowski Szymon , Poleski Radosław , Skowron Jan , Ulaczyk Krzysztof , Gromadzki Mariusz , Rybicki Krzysztof , Iwanek Patryk , Wrona Marcin , Mróz Mateusz J. ,   (The OGLE Collaboration), Albrow Michael D. , Chung Sun-Ju , Han Cheongho , Hwang Kyu-Ha , Jung Youn Kil , Shin In-Gu , Shvartzvald Yossi , Yee Jennifer C. , Zang Weicheng , Cha Sang-Mok , Kim Dong-Jin , Kim Seung-Lee , Lee Chung-Uk , Lee Dong-Joo , Lee Yongseok , Park Byeong-Gon , Pogge Richard W. ,   (KMTNet Collaboration)
Published: February 2025

Abstract
Interferometric observations of gravitational microlensing events offer an opportunity for precise, efficient, and direct mass and distance measurements of lensing objects, especially those of isolated neutron stars and black holes. However, such observations have previously been possible for only a handful of extremely bright events. The recent development of a dual-field interferometer, GRAVITY Wide, has made it possible to reach out to significantly fainter objects and increase the pool of microlensing events amenable to interferometric observations by 2 orders of magnitude. Here, we present the first successful observation of a microlensing event with GRAVITY Wide and the resolution of microlensed images in the event OGLE-2023-BLG-0061/KMT-2023-BLG-0496. We measure the angular Einstein radius of the lens with subpercent precision, θ
E = 1.280 ± 0.009 mas. Combined with the microlensing parallax detected from the event light curve, the mass and distance to the lens are found to be 0.472 ± 0.012 M
⊙ and 1.81 ± 0.05 kpc, respectively. We present the procedure for the selection of targets for interferometric observations and discuss possible systematic effects affecting GRAVITY Wide data. This detection demonstrates the capabilities of the new instrument, and it opens up completely new possibilities for the follow-up of microlensing events and future routine discoveries of isolated neutron stars and black holes.
The Effects of Active Galactic Nuclei Feedback on the Lyα Forest Flux Power Spectrum
Authors: Tillman Megan Taylor , Burkhart Blakesley , Tonnesen Stephanie , Bird Simeon , Bryan Greg L. 
Published: February 2025

Abstract
We study the effects of active galactic nuclei (AGN) feedback on the Lyα forest 1D flux power spectrum (P1D). Using the Simba cosmological-hydrodynamic simulations, we examine the impact that adding different AGN feedback modes has on the predicted P1D. We find that, for Simba, the impact of AGN feedback is most dramatic at lower redshifts (z < 1) and that AGN jet feedback plays the most significant role in altering the P1D. The effects of AGN feedback can be seen across a large range of wavenumbers (1.5 × 10−3 < k < 10−1 s km−1) changing the ionization state of hydrogen in the IGM through heating. AGN feedback can also alter the thermal evolution of the IGM and thermally broaden individual Lyα absorbers. For the Simba model, these effects become observable at z ≲ 1.0. At higher redshifts (z > 2.0), AGN feedback has a 2% effect on the P1D for k < 5 × 10−2 s km−1 and an 8% effect for k > 5 × 10−2 s km−1. We show that the small-scale effect is reduced when normalizing the simulation to the observed mean flux. On large scales, the effect of AGN feedback appears via a change in the IGM temperature and is thus unlikely to bias cosmological parameters. The strong AGN jets in the Simba simulation can reproduce the z > 2 Lyα forest. We stress that analyses comparing different AGN feedback models to future higher precision data will be necessary to determine the full extent of this effect.
Influence of Effective Nucleon Mass on Equation of State for Supernova Simulations and Neutron Stars
Authors: Li Shuying , Pang Junbo , Shen Hong , Hu Jinniu , Sumiyoshi Kohsuke 
Published: February 2025

Abstract
We investigate the influence of the effective nucleon mass on the equation of state (EOS), which is constructed for simulations of core-collapse supernovae and binary neutron star mergers, within the relativistic mean-field (RMF) framework. The study introduces a new RMF parameter set, TM1m, which is a modification of the TM1e model with an adjusted effective mass, maintaining the saturation properties of nuclear matter. The TM1m model, with a larger effective mass ratio (M
*/M ~ 0.8) compared to the TM1e model (M
*/M ~ 0.63), is employed to construct a new EOS table, EOS5. This EOS table is designed to offer insights into the influence of the effective nucleon mass on the EOS within a relativistic framework, particularly above the saturation density. The results of EOS5 are compared with those obtained from other models, including both relativistic and nonrelativistic approaches. The properties of cold neutron stars, calculated using the TM1m model, are compatible with the existence of a 2 M
⊙ pulsar and the latest constraints on the tidal deformability and radii of a canonical 1.4 M
⊙ neutron star, derived from astrophysical observations.