bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reliability of the Harris Hip limping sub-score in patients undergoing total hip arthroplasty
Authors: Rose-Dulcina Kevin , Gasparutto Xavier , Djebara Az-Eddine , Gauthier Morgan , Zingg Matthieu , Lübbeke Anne , Armand Stéphane , Hannouche Didier 
Published: January 2024

Abstract
Purpose
In patients undergoing total hip arthroplasty, limping is a significant symptom, often assessed with the limping sub-score of the Harris Hip Score. However, the reliability of this sub-score has not been specifically investigated. The purpose of this study is to investigate the intra- and inter-rater reliability of this sub-score.

Methods
Thirty patients undergoing THA were recruited and performed a gait analysis before surgery and three months after surgery. In addition, 30 asymptomatic participants were included. In total, 90 visits were analysed in this study. The HHS limping sub-score was assessed for each visit using a video (front and back view side-by-side) of a ten metre walk at a self-selected speed. Two orthopaedic surgeons evaluated the limping of each video in two different grading sessions with a one week delay. To avoid recall bias, the patient’s number identity was randomized and different for each grading session and each rater. The weighted Cohen’s Kappa coefficient was used to quantify the intra- and inter-reliability. The reliability of three components was studied: the presence of limping, its severity, and the compensation type.

Results
For all components, the agreement for intra-rater reliability ranged from moderate to strong and from none to moderate for the inter-rater reliability.

Conclusion
These results do not encourage the use of HHS-limping sub-score for data involving different raters in both clinical and research contexts. It calls for improved consensus on limping definitions or the creation of objective measures.
Relocation of lower pole renal stones helps improve the stone-free rate during flexible ureteroscopy with a low complication rate
Authors: Huang Ru , Chen Jian-chun , Zhou Yong-qiang , Wang Jin-jin , Hui Chu-chu , Jiang Min-jun , Xu Chen 
Published: January 2024

Abstract
Objective
To compare the efficacy and safety of relocating the lower pole stones to a favorable pole during flexible ureteroscopy with in situ lithotripsy for the treatment of 10–20 mm lower pole stone (LPS).

Methods
This study was a prospective analysis of patient outcomes who underwent an FURS procedure for the treatment of 10–20 mm lower pole renal stones from January 2020 to November 2022. The patients were randomized into a relocation group or in situ group. The LPSs were relocated into a calyx, during lithotripsy in the relocation group was performed, whereas the in situ group underwent FURS without relocation. All the procedures were performed by the same surgeon. The patients’ demographic data, stone characteristics, perioperative parameters and outcomes, stone-free rate (SFR), complications, and overall costs were assessed retrospectively.

Results
A total of 90 patients were enrolled and analyzed in this study (45 per group) with no significant differences between the two groups in terms of age, gender, BMI, diabetes, hypertension, stone size, number, laterality, composition, and density. The mean operation time, total energy consumption, postoperative stay, and complications were similar between the groups. Both groups had similar SFR at 1 day postoperative follow-up (p = 0.091), while the relocation group achieved significantly higher SFR 3 months later (97.8% vs 84.4%, p = 0.026). The relocation group also had a significantly higher WisQol score than the in situ group (126.98 vs 110.18, p < 0.001).

Conclusion
A satisfactory SFR with a relatively low complication rate was achieved by the relocation technique during the FURS procedure.
Defining the role of multiparametric MRI in predicting prostate cancer extracapsular extension
Authors: Sanguedolce Francesco , Tedde Alessandro , Granados Luisa , Hernández Jonathan , Robalino Jorge , Suquilanda Edgar , Tedde Matteo , Palou Joan , Breda Alberto 
Published: January 2024

Abstract
Objectives
To identify the predictive factors of prostate cancer extracapsular extension (ECE) in an institutional cohort of patients who underwent multiparametric MRI of the prostate prior to radical prostatectomy (RP).

Patients and methods
Overall, 126 patients met the selection criteria, and their medical records were retrospectively collected and analysed; 2 experienced radiologists reviewed the imaging studies. Logistic regression analysis was conducted to identify the variables associated to ECE at whole-mount histology of RP specimens; according to the statistically significant variables associated, a predictive model was developed and calibrated with the Hosmer–Lomeshow test.

Results
The predictive ability to detect ECE with the generated model was 81.4% by including the length of capsular involvement (LCI) and intraprostatic perineural invasion (IPNI). The predictive accuracy of the model at the ROC curve analysis showed an area under the curve (AUC) of 0.83 [95% CI (0.76–0.90)], p < 0.001. Concordance between radiologists was substantial in all parameters examined (p < 0.001). Limitations include the retrospective design, limited number of cases, and MRI images reassessment according to PI-RADS v2.0.

Conclusion
The LCI is the most robust MRI factor associated to ECE; in our series, we found a strong predictive accuracy when combined in a model with the IPNI presence. This outcome may prompt a change in the definition of PI-RADS score 5.
The use of Versius CMR for pelvic surgery: a multicentric analysis of surgical setup and early outcomes
Authors: Sighinolfi Maria Chiara , De Maria Maurizio , Meneghetti Iacopo , Felline Mauro , Ceretti Andrea Pisani , Mosillo Luca , Catalano Chiara , Morandi Alessandro , Calcagnile Tommaso , Panio Enrico , Sangalli Mattia , Turri Filippo , Terzoni Stefano , Assumma Simone , Sarchi Luca , Afonina Margarita , Marconi Annamaria , Bianchi Paolo Pietro , Micali Salvatore , Rocco Bernardo , Gaia Giorgia 
Published: January 2024

Abstract
Introduction
Versius CMR is a novel robotic system characterized by an open surgical console and independent bedside units. The system has potentials of flexibility and versatility, and has been used in urological, gynecological, and general surgical procedure. The aim is to depict a comprehensive analysis of the Versius system for pelvic surgery.

Methods
This is a study involving two Institutions, ASST Santi Paolo and Carlo, Milan, and Apuane Hospital, Massa, Italy. All interventions performed in the pelvic area with the Versius were included. Data about indications, intra-, and post-operative course were prospectively collected and analyzed.

Results
A total of 171 interventions were performed with the Versius. Forty-two of them involved pelvic procedures. Twenty-two had an oncological indication (localized prostate cancer), the remaining had a non-oncological or functional purpose. The mostly performed pelvic procedure was radical prostatectomy (22) followed by annexectomy (9). No intra-operative complication nor conversion to other approaches occurred. A Clavien II complication and one Clavien IIIb were reported. Malfunctioning/alarms requiring a power cycle of the system occurred in 2 different cases. An adjustment in trocar placement according to patients’ height was required in 2 patients undergoing prostatectomy, in which the trocar was moved caudally. In two cases, a pelvic prolapse was repaired concomitant with other gynecological procedures.

Conclusions
Pelvic surgery with the Versius is feasible without major complications; either dissection and reconstructive steps could be accomplished, provided a proper OR setup and trocar placement are pursued. Versius can be easily adopted by surgeons of different disciplines and backgrounds; a further multi-specialty implementation is presumed and long-term oncological and functional outcomes are awaited.
Mid-term results of a cementless hip stem in femoral revision: how much diaphyseal press-fit do we need?
Authors: Herold Dirk , Kuttner Axel , Dreyer Lutz , Eingartner Christoph 
Published: January 2024

Abstract
Introduction
The aim of this retrospective study was to analyze the clinical and functional outcome of a modular tapered revision hip stem after mid-term follow-up with a special focus on the length of the distal bicortical fixation of the cementless hip stem.

Materials and Methods
Follow-up examination was carried out for all patients with implantation of the Prevision hip stem between 2014 and 2019 to collect demographic, functional, and radiographic data.

Results
44 patients with stem in situ were examined, and 61 patients could be included in the Kaplan–Meier survival analysis. Oxford’s hip score was 37.3 at the mean follow-up of 4.0 years. Two hip stem revisions were performed due to periprosthetic infection, which resulted in a hip stem survival rate of 96.7% (CI: 87.4–99.1%) at the final follow-up of 7.5 years. No aseptic hip stem revision was required. The length of bicortical distal fixation was in the interquartile range of 6.8 to 9.0 cm, which was associated with good bone healing and a low rate of subsidence (4.5%). Implant-associated complications were observed in 10 cases (21.7%).

Conclusions
The modular revision hip stem provides promising results at medium-term follow-up, with satisfactory clinical and functional outcomes comparable to other modular revision hip stems. The presented length of bicortical distal fixation shows the practice of the study center and was associated with good implant survival, bone healing and radiological results.

Registration
Clinicaltrials.gov registration: NCT04833634 registered on April 6, 2021
Peritoneal mesometrial resection with lymphadenectomy following prior hysterectomy in intermediate/high-risk endometrial cancer: feasibility and safety
Authors: Buderath Paul , Elgharib Mohamed , Kimmig Rainer 
Published: January 2024

Abstract
Objective
Peritoneal mesometrial resection (PMMR) plus targeted compartmental lymphadenectomy (TCL) aims at removal of the locoregional cancer field in endometrial cancer (EC). Optimal locoregional control without adjuvant radiotherapy should be achieved concomitantly sparing systematic lymphadenectomy (LNE) for most of the patients. However, intermediate/high-risk EC is often definitely diagnosed postoperatively in simple hysterectomy specimen. Our aim was to evaluate feasibility and safety of a completing PMMR + TCL in patients following prior hysterectomy.

Methods
We evaluated data from 32 patients with intermediate/high-risk EC treated with PMMR + TCL or systematic pelvic and periaortic LNE following prior hysterectomy. Perioperative data on disease characteristics and morbidity were collected and patients were contacted for follow-up to determine the recurrence and survival status.

Results
We report data from 32 patients with a mean follow-up of 31.7 months. The recurrence rate was 12.5% (4/32) without any isolated locoregional recurrences. Only 21.9% of patients received adjuvant radiotherapy. Rates of intra- and postoperative complications were 6.3% and 18.8%, respectively.

Conclusion
Our data suggest that robotic PMMR can be performed following prior hysterectomy when previously unknown risk factors arise, albeit with a moderate increase in morbidity. Moreover, despite a relevant reduction of adjuvant radiotherapy, follow-up data suggest an excellent locoregional control even without adjuvant radiotherapy.
The effectiveness of integrated online health-coaching on physical activity and excessive gestational weight gain: a prospective randomized-controlled trial
Authors: Téoule Julia , Woll Christian , Ray Jana , Sütterlin Marc , Filsinger Barbara 
Published: January 2024

Abstract
Purpose
Low levels of physical activity during pregnancy go along with increased risks for numerous health complications. We investigated whether an integrated lifestyle intervention leads to higher levels of physical activity and reduces the rate of excessive gestational weight gain (EGWG).

Methods
We conducted a randomized-controlled trial on 97 pregnant women, randomly assigned to receive an additional telehealth lifestyle intervention (experimental group, EG; n = 49) or conventional antenatal care (control group, CG; n = 48). The core lifestyle intervention comprised regular video calls, providing integrated personal support and motivation to physical activity. The primary outcome was change in physical activity measured in steps per day. An additional exploratory outcome was the proportion of participants with EGWG.

Results
The mean step count during the third trimester was 6483 steps/day (EG) and 5957 steps/day (CG), respectively (p = 0.078). Repeated-measures ANOVA revealed a significant interaction effect (p = 0.045) reflecting an overall increase of 497 steps per day in the EG vs. a decrease of 300 steps per day in the CG. The proportion of participants who met the IOM recommendation for total weight gain during pregnancy was significantly higher in the EG (p = 0.048) and the ratio of women that gained excessively was higher in the CG (p = 0.026).

Conclusions
We assume that the personalized online intervention supports women in increasing or at least maintaining their level of physical activity during the course of pregnancy. Additionally, it reduces the rate of excessive weight gain.
Porosity generation via spatially uncoupled dissolution precipitation during plagioclase replacement in quartz undersaturated fluids
Authors: Nurdiana Astin , Okamoto Atsushi , Uno Masaoki , Tsuchiya Noriyoshi 
Published: January 2024

AbstractThe replacement of feldspars is commonly characterized by pseudomorphism and reaction-induced pore generation. However, the effects of compositions of feldspars and fluids on porosity generation during alteration are still poorly understood. In this study, we conducted a series of hydrothermal experiments on plagioclase replacement by 2 M KCl or NaCl aqueous solutions at 600 °C and 150 MPa for 1–8 days, using plagioclase with different compositions (anorthite, An96Ab4; labradorite, An66Ab33Or1; albite, An1Ab99) with or without quartz. Albite replacement by K-feldspar was not affected by the presence of quartz, whereas anorthite was unaltered in the quartz-absent fluid. The replacement of labradorite by KCl(aq) showed different results: in the presence of quartz, labradorite was altered by K-feldspar, whereas in the absence of quartz, alteration proceeded significantly with the generation of large pores hosted by secondary anorthite coupled with euhedral K-feldspar overgrowth. Such textural relationship and oxygen isotope-labeled experiments reveal that silica-deficient fluid enhances the uncoupled dissolution reprecipitation process. The Si and Al ions in the reacted aqueous solution diffused outside the labradorite grains and encountered K+-rich solutions to grow K-feldspar. The experiments with polycrystalline rocks composed of amphibole + labradorite using 2 M KCl aqueous solution indicated the replacement of labradorite grains by anorthite and K-feldspar overgrowth, as found in single-crystal experiments. Our results indicate that the silica concentration in the fluids has different influences on the saturation indices of albite, anorthite, and K-feldspars in saline fluids, which significantly affect the replacement textures and porosity generation in crustal rocks.
Are sucking patterns and early spontaneous movements related to later developmental functioning outcomes? A cohort study
Authors: Yardımcı-Lokmanoğlu Bilge N. , Demir Numan , Porsnok Doğan , Sırtbaş-Işık Gülsen , Cengiz Emre , Serel-Arslan Selen , Mutlu Akmer 
Published: January 2024

AbstractSucking patterns and early spontaneous movements have an important role in the determination of later developmental problems, but the relationship of the two together with long-term outcomes has not been investigated. The objectives of this study were to (i) examine the relationship between sucking patterns using the Neonatal Oral Motor Assessment Scale (NOMAS) and fidgety movements and other movement patterns using detailed General Movements Assessment (GMA), and (ii) investigate the relationship between these early assessment methods and developmental functioning outcomes at later ages. We analyzed the NOMAS from 34 weeks’ postmenstrual age up to 10 weeks post-term and GMA between 9 and 20 weeks post-term age, and the Bayley Scales of Infant and Toddler Development-Third Edition (Bayley-III) was applied for the developmental functioning outcomes to 62 infants (61%, 62/102) between 12 and 42 months of age. Among 102 infants at-risk, 70 (69%) showed a normal sucking pattern, and 85 (83%) had fidgety movements. The median Motor Optimality Score-Revised (MOS-R), as determined by GMA, of all infants was 24. The NOMAS was related to the MOS-R and its subcategories (p < 0.05) in all infants at-risk. The NOMAS, MOS-R and its subcategories were also related to cognitive, language, and motor development at later ages according to Bayley-III (p < 0.05). Conclusion: This longitudinal study showed that the quality of sucking patterns, fidgety movements, and MOS-R were related to later developmental functioning, indicating that abnormal sucking patterns, aberrant fidgety movements, and lower MOS-R might predict developmental disorders.

What is Known:• Sucking patterns and early spontaneous movements in which central pattern generators play an important role are related.• Sucking patterns and early spontaneous movements might be used separately to predict developmental outcomes.

What is New:• Sucking patterns and early spontaneous movements, when used together, were related to later developmental functioning, including cognitive, language, and motor development in at-risk infants.• Predictive value of sucking patterns was lower for each developmental functioning outcome than early spontaneous movements.
Biometric systems for identification and verification scenarios using spatial footsteps components
Authors: Iskandar Ayman , Alfonse Marco , Roushdy Mohamed , El-Horbaty El-Sayed M. 
Published: January 2024

AbstractHumans are distinguished by their walking patterns; many approaches, including using various types of sensors, have been used to establish walking patterns as biometrics. By studying the distinguishing features of a person's footsteps, footstep recognition may be utilized in numerous security applications, such as managing access in protected locations or giving an additional layer of biometric verification for secure admittance into restricted regions. We proposed biometric systems for verifying and identifying a person by acquiring spatial foot pressure images from the values obtained from the piezoelectric sensors using the Swansea Foot Biometric Database, which contains 19,980 footstep signals from 127 users and is the most prominent open-source gait database available for footstep recognition. The images acquired are fed into the ConvNeXt model, which was trained using the transfer learning technique, using 16 stride footstep signals in each batch with an Adam optimizer and a learning rate of 0.0001, and using sparse categorical cross-entropy as the loss function. The proposed ConvNeXt model has been adjusted to acquire 512 feature vectors per image, and these feature vectors are used to train the logistic regression models. We propose two biometric systems. The first biometric system is based on training one logistic regression model as a classifier to identify 40 different users using 1600 signals for training, 6697 signals for validation, and 200 signals for evaluation. The second biometric system is based on training 40 logistic regression models, one for each user, to validate the user's authenticity, with a total number of 2363 training signals, 7077 validation signals, and 500 evaluation signals. Each of the 40 models has a 40-training signal per client and a different number of signals per imposter, a different number of signals for the validation that ranges between 8 and 650 signals, a 5-signal for an authenticated client, and a different number of signals per imposter for evaluation. Independent validation and evaluation sets are used to evaluate our systems. In the biometric identification system, we obtained an equal error rate of 15.30% and 21.72% for the validation and evaluation sets, while in the biometric verification system, we obtained an equal error rate of 6.97% and 10.25% for the validation and evaluation sets.
Efficient CNN-based low-resolution facial detection from UAVs
Authors: Diez-Tomillo Julio , Martinez-Alpiste Ignacio , Golcarenarenji Gelayol , Wang Qi , Alcaraz-Calero Jose M. 
Published: January 2024

AbstractFace detection in UAV imagery requires high accuracy and low execution time for real-time mission-critical operations in public safety, emergency management, disaster relief and other applications. This study presents UWS-YOLO, a new convolutional neural network (CNN)-based machine learning algorithm designed to address these demanding requirements. UWS-YOLO’s key strengths lie in its exceptional speed, remarkable accuracy and ability to handle complex UAV operations. This algorithm presents a balanced and portable solution for real-time face detection in UAV applications. Evaluation and comparison with the state-of-the-art algorithms using standard and UAV-specific datasets demonstrate UWS-YOLO’s superiority. It achieves 59.29% of accuracy compared with 27.43% in a state-of-the-art solution RetinaFace and 46.59% with YOLOv7. Additionally, UWS-YOLO operates at 11 milliseconds, which is 345% faster than RetinaFace and 373% than YOLOv7.
Antibacterial and clinical effectiveness of a mouthwash with a novel active system of amine + zinc lactate + fluoride: a randomized controlled trial
Authors: Montesani Lorenzo , Montesani Luigi , Mateo Luis , Daep Carlo , Huber Norbert , Isapour Golnaz , Zhang Yun-Po 
Published: January 2024

Abstract
Objectives
To support the daily oral hygiene of patients experiencing gum inflammation, a new mouthwash was developed containing an amine + zinc lactate + fluoride system. In vitro and clinical efficacy was assessed using traditional methods as well as using novel site-specific and subject-specific analyses of the clinical data.

Materials and methods
This mouthwash was evaluated in a 12-h biofilm regrowth assay against a negative control mouthwash and in a 6-month plaque and gingivitis clinical study as compared to a negative control mouthwash. Analyses of healthy versus inflamed sites, visible plaque versus non-visible plaque sites, as well as subject-level evaluations bring new perspectives to the overall performance of this mouthwash and its significance from a patient outcome perspective.

Results
Studies demonstrated that this new mouthwash provided long-term (12-h) antibacterial activity after single application in vitro and reduced clinically all plaque and gingivitis parameters after 3 months and 6 months of use when compared to the negative control mouthwash. Examination of site-level and subject-level data determined that this mouthwash significantly increased the number of healthy sites in the oral cavity and significantly improved the gum health of subjects in the study, as compared to the negative control mouthwash.

Conclusions
In vitro and clinical research has demonstrated the antibacterial and clinical benefits of this mouthwash containing an amine compound + zinc lactate + fluoride system.

Clinical relevance
Our subject-specific and site-specific analyses provide the dental practitioner with tools that can be used to guide patients who suffer from gingivitis toward optimal product selection and use.

Clinical trial registration
The trial was registered at ClinicalTrials.gov (reference no. NCT05821712).