bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rapid, systematic updating of movement by accumulated decision evidence
Authors: Molano-Mazón Manuel , Garcia-Duran Alexandre , Pastor-Ciurana Jordi , Hernández-Navarro Lluís , Bektic Lejla , Lombardo Debora , de la Rocha Jaime , Hyafil Alexandre 
Published: November 2023

AbstractActing in the natural world requires not only deciding among multiple options but also converting decisions into motor commands. How the dynamics of decision formation influence the fine kinematics of response movement remains, however, poorly understood. Here we investigate how the accumulation of decision evidence shapes the response orienting trajectories in a task where freely-moving rats combine prior expectations and auditory information to select between two possible options. Response trajectories and their motor vigor are initially determined by the prior. Rats movements then incorporate sensory information as early as 60 ms after stimulus onset by accelerating or slowing depending on how much the stimulus supports their initial choice. When the stimulus evidence is in strong contradiction, rats change their mind and reverse their initial trajectory. Human subjects performing an equivalent task display a remarkably similar behavior. We encapsulate these results in a computational model that, by mapping the decision variable onto the movement kinematics at discrete time points, captures subjects’ choices, trajectories and changes of mind. Our results show that motor responses are not ballistic. Instead, they are systematically and rapidly updated, as they smoothly unfold over time, by the parallel dynamics of the underlying decision process.
High-quality genome assembly of a white eared pheasant individual and related functional and genetics data resources
Authors: Wu Siwen , Wang Kun , Dou Tengfei , Yuan Sisi , Wu Dong-Dong , Su Zhengchang , Ge Changrong , Jia Junjing 
Published: November 2023

AbstractWhite eared pheasant (WT), (Crossoptilon crossoptilon), inhibiting at high altitudes (3000∼4,300 m), is a Galliformes bird native to the Qinghai, Sichuan, Yunnan and Tibet Province of China. Due to the difficulty of sequencing the precious species, there is no high-quality genome assembly for the species, hampering the understanding of their genetic mechanisms. To fill the gap, we sequenced and assembled a WT individual using Illumina short reads, PacBio long reads and Hi-C reads. With a contig N50 of 19.63 Mb, scaffold N50 of 29.59 Mb, total length of 1.02 Gb and BUSCO completeness of 97.2%, the assembly is highly complete. Evaluation shows that the assembly is at chromosome-level with only six gaps. Thus, our assembly provides a valuable genetic resource for thecrossoptilonspecies. To further provide resources for gene annotation and population genetics analysis, we also sequenced transcriptomes of 20 tissues of the WT individual and re-sequenced another 10 individuals of WT. Our assembled WT genome and the sequencing data can be valuable resources to study thecrossoptilonspecies.
Acetylation of H3K115 at the nucleosome dyad is associated with fragile nucleosomes at active regulatory sites
Authors: Sengupta Dipta , Friman Elias T. , Illingworth Robert S. , Bickmore Wendy A. , Kumar Yatendra 
Published: November 2023

AbstractAcetylation of lysine residues in the tail domain of histone H3 is well characterized. However, acetyl-lysines in the histone globular domain also hold regulatory potential because of their impact on nucleosome dynamics and stability. In this study, we report the genome-wide distribution of acetylated H3 lysine 115 (H3K115ac), a residue on the lateral surface at the nucleosome dyad, in mouse embryonic stem cells. We find that H3K115ac is associated with highly active promoters, particularly those associated with CpG islands, and with enhancers. During differentiation H3K115ac is dynamic, changing in line with gene activation and chromatin accessibility. Most strikingly, unlike other commonly studied histone acetylation marks, H3K115ac is enriched on “fragile” nucleosomes within the nucleosome depleted regions of active promoters, and enhancers where it coincides with transcription factor binding. Additionally, we detect H3K115ac-marked fragile nucleosomes at sites most strongly occupied by CTCF, within the CTCF footprint and oriented relative to the CTCF motif. This unusual genomic distribution suggests that H3K115ac could have a role in nucleosome destabilization and that it might be a valuable marker for identifying functionally important regulatory elements in mammalian genomes.
Insights into B Cell and Antibody Kinetics Against SARS-CoV-2 Variants Using Mathematical Modelling
Authors: Farhang-Sardroodi Suzan , Deng Xiaoyan , Portet Stéphanie , Arino Julien , Craig Morgan 
Published: November 2023

AbstractB cells and antibodies are crucial in protecting against infections like SARS-CoV-2. However, antibody levels decline after infection or vaccination, reducing defences against future SARS-CoV-2 infections. To understand antibody production and decline, we developed a mathematical model that predicts germinal center B cell, long-lived plasma cell, memory B cell, and antibody dynamics. Our focus was on B cell activation and antibody generation following both primary and secondary SARS-CoV-2 infections. Aligning our model with clinical data, we adjusted antibody production rates for germinal center B cells and plasma B cells during primary and secondary infections. We also assessed antibody neutralization against Delta and Omicron variants post-primary and secondary exposure. Our findings showed reduced neutralization against Omicron due to its immune evasion. In primary and secondary exposures to Delta and Omicron, our predictions indicated enhanced antibody neutralization in the secondary response within a year of the primary response. We also explored waning immunity, demonstrating how B cell kinetics affect viral neutralization post-primary infection. This study enhances our understanding of humoral immunity to SARS-CoV-2 and can predict antibody dynamics post-infection or vaccination.
Cardiometabolic Health in Asian American Children
Authors: Sethna Julian , Wong Kristal , Meyers Kevin 
Published: November 2023

AbstractBackgroundThe aim was to compare cardiometabolic health between Asian American children and Non-Hispanic White (NHW) children as well as to compare cardiometabolic health among Asian American children by birthplace.MethodsChildren aged 6-17 years enrolled in the National Health and Nutrition Examination Survey (NHANES) from 2011-2018 who self-identified as non-Hispanic Asian and NHW were included. Among Asian Americans, place of birth was defined as foreign-born vs United States (US)-born. Regression models were adjusted for age, sex, household income, food insecurity, passive smoke exposure, and body mass index (BMI) z-score.ResultsAmong 3369 children, 8.4% identified as Asian American (age 11.7 years) and 91.6% identified as NHW (age 11.7 years). Compared to NHW children, Asian American children had significantly lower BMI z-scores and odds of obesity. Asian American children had higher HOMA-IR and uric acid, and greater odds of dyslipidemia, microalbuminuria and glomerular hyperfiltration compared to NHW children. Among Asian Americans, 30.5% were foreign-born. Compared to foreign-born Asian American children, US-born Asian American children had significantly higher non-HDL, triglycerides, HOMA-IR and uric acid, lower HDL, and lower odds of hyperfiltration. There were no differences in blood pressure by racial group or place of birth.ConclusionsAlthough Asian American children have lower odds of obesity, they have significantly worse glucose intolerance, higher serum uric acid levels, more dyslipidemia and more microalbuminuria compared to NHW children. US-born Asian American children have worse cardiometabolic health profiles compared to foreign-born Asian Americans.
Captivity affects mitochondrial aerobic respiration and carotenoid metabolism in the house finch (Haemorhous mexicanus)
Authors: Koch Rebecca E. , Okegbe Chidimma , Ramanathan Chidambaram , Zhu Xinyu , Hare Ethan , Toomey Matthew B. , Hill Geoffrey E. , Zhang Yufeng 
Published: November 2023

ABSTRACTIn many species of animals, red carotenoid-based coloration is produced by metabolizing yellow dietary pigments, and this red ornamentation is an honest signal of individual quality. However, the physiological basis for associations between organism function and the metabolism of red ornamental carotenoids from yellow dietary carotenoids remains uncertain. A recent hypothesis posits that carotenoid metabolism depends on mitochondrial performance, with diminished red coloration resulting from altered mitochondrial aerobic respiration. To test for an association between mitochondrial respiration and red carotenoids, we held wild-caught, molting male house finches in either small bird cages or large flight cages to create environmental challenges during the period when red ornamental coloration is produced. We predicted that small cages would present a less favorable environment than large flight cages and that captivity would affect both mitochondrial performance and the abundance of red carotenoids. We found no evidence that living in smallversuslarge cages had significant effects on wild-caught house finches; however, birds in cages of any size circulated fewer red carotenoids, showed increased mitochondrial respiratory rates, and had lower complex II respiratory control ratios—a metric associated with mitochondrial efficiency—compared to free-living birds. Moreover, among captive individuals, the birds that circulated the most red carotenoids had the highest mitochondrial respiratory control ratio for complex II substrates. These data support the hypothesis that the metabolism of red carotenoid pigments is linked to mitochondrial aerobic respiration in the house finch, but the mechanisms for this association remain to be established.SUMMARY STATEMENTHolding wild-caught male house finches in cages exposed a relationship between red carotenoid production and mitochondrial respiratory efficiency.
Structure-property machine learning models with predictive capabilities for glycans in food
Authors: Naravane Tarini , Simmons Gabriel 
Published: November 2023

ABSTRACTStructure-property predictive models for food aim to decipher the complex relation between the physical shape of a molecule and its physical properties and/or the functional role of the molecule in a product formulation. Our focus in this paper is the modeling of glycans (i.e., carbohydrates), which are not only abundant in food, but essential to both food production and, more importantly, human health. In our study, we use regression methods to generalize the relationships between the structure of starch (e.g., chain length and composition of protein and amylose) and a range of its properties (e.g., gelatinization temperature, time series viscosity data, gel consistency, and sensory texture) for 301 samples of rice. Our results indicate that the structure-composition data is a significantly better predictor of sensory mouthfeel than the physical properties, even though the latter is typically used in experimental research. This demonstrates the potential to harness several structure-property relationships and we provide strategies to accelerate further experiment-based research.
Breaking the vertical barrier: effects of vertical direction and rotation of an English loan brand name on product evaluation
Authors: Park Jihye , Zhang Min , Yoo Seunghyun , Kwon Hannah Gloria 
Published: November 2023

PurposeThis study investigates the effects of vertical direction and rotation of English loan brand names in East Asian languages (Chinese and Korean) on processing fluency, perceived product quality and purchase intention.Design/methodology/approachFour experiments were conducted in China and Korea, employing a 2 (vertical direction: downward vs upward) X 3 (rotation: 0°/marquee vs 90° clockwise vs 90° counterclockwise) between-subjects factorial design.FindingsThe findings showed that when the English loan Chinese brand name was displayed downward, the marquee format was preferred, while counterclockwise rotation was favored when displayed upward. In Korean, clockwise rotation was preferred for downward presentation, while counterclockwise rotation was favored for upward presentation. The effects on purchase intention were mediated by processing fluency and perceived product quality.Practical implicationsThis research provides practical implications for global manufacturers and retailers, offering guidance on presenting brand names in East Asian languages and optimizing product packaging designs. For Chinese consumers, the marquee format is recommended for downward-oriented brand names, while counterclockwise rotation is effective for upward orientation. For Korean consumers, clockwise rotation is favored for downward presentation and counterclockwise rotation is preferred for upward presentation. Understanding linguistic habits allows the tailoring of brand presentations, enhancing brand perception and consumer responses.Originality/valueThis study contributes to understanding the role of cultural and linguistic influences on consumer information processing and product perception in vertical presentations of brand names.
Linking innovation and firm performance in an emerging market: does supply chain play a mediation role?
Authors: Nguyen Van It , Kotaskova Anna , Ferraris Alberto , Le Thanh Tiep 
Published: November 2023

Purpose This study investigates the impact of human capital (managers' capital, employees' capital) and orientation (market orientation, entrepreneurial orientation) for accelerating the digitalization process and improving the firm performance. It also studies the role of supply chains as both direct and indirect mediators of the correlation between digitalization and business performance.Design/methodology/approachThis article aims to develop an empirical study using a random sampling technique and survey data collected from 368 managers and owners of different food enterprises in Vietnam. The study adopted a methodological approach quantitatively. Analysis of the relationships and confirmatory factors was performed using structural equation modeling (SEM), a technique to evaluate the proposed relationships.FindingsIn line with expectations, the findings emphasize the impact of human capital (managers' capital, employees' capital) and orientation (market orientation, entrepreneurial orientation) for accelerating the digitalization process and the role of supply chains as both direct and indirect mediators of the correlation between digitalization and improving the firm performance, in the context of emerging markets.Originality/valueThis is an important investigation, according to the authors' knowledge, regarding the role of developing human capital (managers' capital, employees' capital) and orientation (market orientation, entrepreneurial orientation) as a key strategy for accelerating the digitalization process and improving the firm performance. Further, the study's novelty reinforces the role of supply chains as both direct and indirect mediators of the correlation between digitalization and business performance in the Vietnamese food companies, where a market economy is emerging.
Should I stay or should I go: how pay secrecy influences turnover intentions
Authors: Rodrigue Shelly , Cox Susie 
Published: November 2023

PurposeThe purpose of this study is to extend the pay communication literature by examining the relationship between pay secrecy and turnover intentions with the inclusion of mediators. This study further analyzes the influence pay secrecy and organizational trust have on three key employee attitudinal variables that are directly related to turnover intentions.Design/methodology/approachThe data were collected from participants that were recruited using Mechanical Turk, yielding a sample size of 496. Structural equation modeling (SEM) was used to analyze the hypotheses.FindingsFindings demonstrate pay secrecy positively influences turnover intentions. This relationship is double-mediated by organizational trust with organizational cynicism, organizational disidentification, and job embeddedness. All hypotheses were supported.Practical implicationsThis research shows that pay secrecy has negative effects on employee attitudes and behaviors. Based on the findings of this study, organizations should take steps toward pay openness to avoid employees becoming distrustful and more cynical of the organization, boost feelings of being embedded, and deter organizational disidentification.Originality/valueThis study contributes to the pay communication literature by further explaining the pay secrecy–turnover intentions relationship with the inclusion of mediators that have shown mixed results or have not been previously analyzed to the researchers' knowledge. Specifically, organizational trust, organizational cynicism, organizational disidentification, and job embeddedness were examined as mediators. Previous research has shown mixed results for the influence pay secrecy has on organizational trust, with some studies demonstrating pay secrecy to have a positive effect and others a negative effect. This study demonstrates support for pay secrecy's negative relationship with organizational trust.
The moderating role of high- and low-involvement product types on customer loyalty and satisfaction in banking: an Australian perspective
Authors: Hinchcliff Mercedez , Kyriazis Elias , McCarthy Grace , Mehmet Michael 
Published: November 2023

PurposeThe study aims to develop a holistic model identifying the constructs that impact customer loyalty in retail banking and introduce product type as a moderating variable to the model.Design/methodology/approachA conceptual model of customer loyalty is introduced and empirically tested with 416 valid samples obtained from Australian retail banking customers. The data were analysed using partial least squares structural equation modelling and multigroup analysis.FindingsThis study confirms the moderating effect of high- and low-involvement products on the relationship between customer loyalty and satisfaction, trust, service quality, commitment and perceived value. Surprisingly, the effect of satisfaction on loyalty was much stronger with low-involvement product types and the effect of commitment on loyalty was much stronger with customers who utilise high-involvement products.Research limitations/implicationsThe study uses a sample population in Australia who utilise one of the top four banks and investigates three product types. Further research could expand the product selection and include customers who use credit unions and other banks not in the top four categories.Originality/valueThis study is the first to confirm the moderating effect product type has on the customer loyalty relationship in retail banking in regard to high- and low-involvement product categories. The research provides a deeper understanding of the factors that influence customer loyalty and identifies which types of products influences customer loyalty the most. Additionally, this study highlights the importance of understanding the different needs and priorities of customers using different product types in order to effectively influence their loyalty.
From disclosure to sustainable performance: how corporate social responsibility disclosure impacts the long-term share price performance of Malaysian IPO
Authors: Abbas Yasir Abdullah , Ahmad-Zaluki Nurwati A. , Mehmood Waqas 
Published: November 2023

PurposeThis paper examines the relationship between the extent and quality of the four dimensions of corporate social responsibility disclosure (CSRD) namely community, environment, workplace and marketplace with the long-run share price performance of Malaysian initial public offering (IPO) companies.Design/methodology/approachThis study utilised secondary data by the content analysis of the annual reports and Datastream of 115 IPOs listed from 2007 to 2015 in Malaysia. The IPO’s performance was determined by calculating the return measures under the equally weighted and value-weighted schemes of the mean abnormal returns and buy-and-hold abnormal returns covering the three years post-listing using the event-time approach.FindingsThe findings demonstrate that Malaysian IPOs experience substantial overperformance and underperformance when both the IPO performance measures are benchmarked against the matched companies and market. The results indicated that the extent and quality of the community and environment CSRD dimensions are positively and significantly correlated to the IPO’s performance. On the other hand, the extent and quality of the workplace and marketplace CSRD dimensions are negatively and significantly correlated to the IPO performance.Practical implicationsMalaysian regulators could benefit from these findings in their endeavour to carry out a reform process on CSRD to improve its quality. The results of this study are important to investors, regulators, non-government organisations, communities and policymakers. They also enhance the understanding of companies about the importance of disclosing greater CSR information to improve their performance and profitability.Originality/valueTo the researchers' best knowledge, this study provides new insights into the association between CSRD and the performance of Malaysian IPO companies, which is considered important.
Does circular economy entrepreneurship drive technical capabilities for circular economy performance? The moderating role of environmental dynamism
Authors: Baah Charles , Rijal Anita , Agyabeng-Mensah Yaw , Afum Ebenezer , Acquah Innocent Senyo Kwasi 
Published: November 2023

Purpose Drawing on the resource-based view (RBV) and the dynamic capabilities view (DCV), this study investigates how circular economy entrepreneurship (CEE) drives technical capabilities (TC) in achieving greater circular economy (CE) performance for small and medium-sized enterprises (SMEs) under the moderating influence of environmental dynamism. SMEs, facing resource constraints, need to promote CE due to growing stakeholder pressures. Thus, the authors recommend that SMEs via CEE can identify CE opportunities and then develop specific TC to exploit opportunities in the business environment to achieve CE performance. However, in doing so SMEs should pay attention to the varying degrees of environmental dynamism.Design/methodology/approach The RBV and DCV are used as a theoretical lens to investigate the direct and moderation effects between CEE, TC, CE performance and environmental dynamism tested via partial least square structural equation modeling (PLS-SEM) using survey data from 152 managers of SMEs in Nepal.Findings The study results show that CEE directly has a positive and significant effect on the development of TC and CE performance. Similarly, the development of TC drives SMEs to achieve improved CE performance, as evidenced by the positive and significant effect. Interestingly, the results suggest that environmental dynamism significantly improves the relationship between TC and CE performance, but this effect is strongest at high levels of environmental dynamism rather than at low and moderate levels. Additionally, the findings reveal that while environmental dynamism has a positive effect on the relationship between CEE and TC, this effect is insignificant.Originality/value Based on the arguments of the RBV and the DCV, this study explores how environmental dynamism can reduce and amplify SMEs' ability to use CEE to develop TC and improve CEP. First, this study integrates the circular economy and entrepreneurship domains to suggest essential CEP and TC benefits for SMEs via CEE. Second, this study suggests that at low levels of environmental dynamism, CEE has less effect on the SMEs’ development of TC, compared to high levels. Third, this study is conducted in the novel institutional context of Nepal, providing insights regarding how SMEs' CE entrepreneurship impacts TC and CEP.