bluuebunny/crossref_metadata_2025_split huggingface dataset:
CTA-Net: A Gaze Estimation network based on Dual Feature Aggregation and Attention Cross Fusion
Authors: Xia Chenxing , Tao Zhanpeng , Wang Wei , Zhao Wenjun , Ge Bin , Gao Xiuju , Li Kuan-Ching , Zhang Yan 
Published: September 2023

Abstract

Recent work has demonstrated the Transformer model is effective for computer vision tasks. However, the global self-attention mechanism utilized in Transformer models does not adequately consider the local structure and details of images, which may result in the loss of information and local details, causing decreased estimation accuracy in gaze estimation tasks when compared to convolution or sequential stacking methods. To address this issue, we propose a parallel CNNs-Transformer aggregation network (CTA-Net) for gaze estimation, which fully leverages the advantages of the Transformer model in modeling global context while the convolutional neural networks (CNNs) model in retaining local details. Specifically, Transformer and ResNet are deployed to extract facial and eye information, respectively. Additionally, an attention cross fusion (ACFusion) Block is embedded with CNN branch, which decomposes features in space and channels to supplement lost features, suppress noise, and help extract eye features more effectively. Finally, a dual-feature aggregation (DFA) module is proposed to effectively fuse the output features of both branches with the help feature a selection mechanism and a residual structure. Experimental results on the MPIIGaze and Gaze360 datasets demonstrate that our CTA-Net achieves state-of-the-art results.
Study on Low Viscosity Hydroxypropyl Methylcellulose Obtained by Electron Beam Irradiation and Its Role in Powder Modification
Authors: Cheng Hong , Wang Youjie , Hong Yanlong , Wu Fei , Shen Lan , Lin Xiao 
Published: September 2023

Abstract
In this study, hydroxypropyl Methylcellulose (HPMC) with lower viscosity was obtained by electron beam irradiation (EBI), and its physical modifiers for pharmaceutical powders was investigated when it was used during spray drying. After HPMC was irradiated at a dose of 150 kGy, the main structure of HPMC was not affected, and the substitution degree of methoxy and hydroxypropyl was not destroyed significantly. As the irradiation dose increased from 10 to 150 kGy, the molecular weight and viscosity of HPMC decreased continuously. The results of spray drying showed that HPMC could quickly migrate to the surface of the liquid medicine to cover droplets during spray drying and atomization, which improved the hygroscopicity and increased the softening point of spray-dried powder. And the powder water content is lower. After the powder is prepared into particles, the dissolution rate of particles is faster. Therefore, the modified powder exhibits better physical properties. The low viscosity HPMC obtained by electron beam irradiation is suitable for powder modification materials during spray drying, and is expected to be developed as excipient in traditional Chinese medicine and other industries.
Factors Associated With Inappropriately Use of Urinary Catheters in Elderly Patients Hospitalized in Internal Medicine Departments
Authors: Shimoni Zvi , Mustarchi Abdoul , Froom Paul 
Published: September 2023

Abstract
Purpose
To identify factors resulting in excess rates of urinary catheterization in elderly hospitalized patients to internal medicine departments.
Methods
We retrospectively selected randomly a sample of about 30% (n = 350) of the hospital charts of 1176/4571 (25.7%) discharged patients aged 65 or older who were newly catheterized and admitted during six months in 2019 and during 3 months in 2021 to one of three internal medicine departments in the Laniado Hospital, a 400-bed regional hospital. The independent variables included patient age, sex, disorientation (demented and or confused), urine volume on catheterization, and serum creatinine. The outcome variables were proportion of patients with inappropriately inserted catheters on admission and not adhering to consensus indications for keeping the catheter in after admission.
Results
There were 25.7% (1176/4571) of patients aged ≥ 65 years with newly placed urinary catheter. From a random sample reviewed, only 11.1% (39 /350) had consensus criteria for an indwelling catheter. There were 144 (41.1%) patients catheterized to obtain a urine sample for culture, not removed after admission in 57 (39.6%). Factors associated with failure to remove the catheter (odds ratios, 95% confidence intervals) included an incidentally detected increase in urine volumes (1.69,1.155–2.47), elevated serum creatinine values (2.71,1.66–4.42), and being disoriented (1.75,1.06–2.87).
Conclusions
Adherence to consensus criteria would have reduced urinary indwelling catheterization rates by nearly 90%, and efforts to ensure removal on admission might focus on those catheterized to obtain a urine sample, those with an incidentally detected increase in urine volumes, and those disoriented.
MAGNETIC ORIENTATION IN ANURANS: A CASE STUDY ON Rhinella arenarum (ANURA: BUFONIDAE)
Authors: Navas Romero Ana Laura , Herrera Moratta Mario Andres , Quiroga Lorena , Sanabria Eduardo , Escudero Consuelo 
Published: September 2023

El campo magnético de la Tierra (EMF) es una de las fuentes de información direccional más uniformes y accesibles que los animales pueden usar en los movimientos de comportamiento. El presente estudio tuvo como objetivo determinar la capacidad de Rhinella arenarum para percibir los campos electromagnéticos. Para evaluar la influencia de los campos electromagnéticos en los anuros in situ, recolectamos cuarenta y cuatro especímenes adultos de R. arenarum durante la temporada de reproducción. Registramos el movimiento de cada sapo desde el centro hasta la periferia de un arenero circular utilizando una cámara de visión nocturna. Repetimos el experimento después de cinco minutos, con un campo magnético inducido adicional (IMF), que fue creado empleando dos bobinas de aire Helmholtz. Los movimientos de los sapos bajo la presencia de EMF y IMF fueron significativamente diferentes. Concluimos que R. arenarum podría usar el EMF como mecanismo de navegación y sistema de ubicación, para viajar largas distancias hasta los estanques de desove año tras año.
Karakterisasi mutu minuman jeli okra nanas dengan kombinasi karagenan-konjak[Characterization of pineapple okra jelly drink quality with different concentrations of carrageenan-konjac combination]
Authors: Amelia Julfi Restu , Pujilestari Shanti , Hamidatun Hamidatun , Monica Putri 
Published: September 2023

ABSTRACTOkra-pineapple jelly drink requires hydrocolloid as a gelling agent. The combination of carrageenan-konjac hydrocolloid used was 75:25 in order to produce acceptable and good quality jelly drink characteristics. This study aimed to characterize the quality of pineapple okra jelly drink with the addition of hydrocolloid (carrageenan-konjac combination). The concentration treatments of the carrageenan-konjac combination 75: 25 in this study were 0.6%, 0.7%, 0.8%, 0.9% and 1%. The research was carried out using a completely randomized design (CRD) experimental method with one factor and 3 replications. Data were analyzed statistically with ANOVA and Duncan multiple range test. The results showed that the concentration of the carrageenan-konjac combination had a significant effect on viscosity, water content, total dissolved solids, hedonic and scoring texture quality tests, but had no significant effect on pH, hedonic and scoring tests for color, taste and aroma. The best concentration of carrageenan-konjac combination in pineapple okra jelly drink was a concentration of 0.9% which had characteristics: viscosity 2488.33 cP, pH 4.05, water content 94.22%, total dissolved solids 5.10º Brix and sensory score from 3.9-4.2 (like) for color, aroma , taste and texture. This best treatment had greenish yellow color, fragrant aroma, sweet taste and slightly chewy texture. The supporting test in the form of antioxidant activity test (IC50) was 16.47 ppm indicated in the very strong category.
Pengaruh penambahan tepung kulit ari kedelai dan tepung wortel terhadap sifat fisikokimia dan sensori mie kering [Effect of the soybean husk and carrot flour addition on the physicochemical and sensory properties of dry noodles]
Authors: Prayitno Sutrisno Adi , Utami Dwi Retnaningtyas , Ningrum Sugiyati , Patria Domas Galih , Putri Silvy Novita Antrisna , Puspita Rizqa Arya , Niam Muhammad Khoirun 
Published: September 2023

Noodles are generally made from wheat flour which is only high in carbohydrates. Meanwhile, noodle products are needed sholud have others nutritional compound that can be used as daily needs consumption. One of them is the utilization of soybean husk which has been only discardes or used as animal feed. The utilazation of soybean husk waste has not been widely used for the food products. Noodles product can be susbtituted for carrots which are rich ini vitamins and carotenoids. Between of them can be substituted into noodle product proccesed. The purpose of this study was to analyze dry noodle products on the effect of soybean epidermis and carrot flour addition on physicochemical and sensory properties. These dry noodles could be used for a healthy menu as an alternative to carbohydrates in rice. There are some previous study about the effect of soybean husk added to the making of biscuit and cookies products that increase status of nutrition, however it was rarely utilized to substitute on the noodle making. Hence, the aim of this study were to utilize of the soybean husk and to analyze dry noodle products on the effect of soybean husk and carrot flour addition on physicochemical and sensory properties. The method of this study was carried out using quantitatve descriptive with prameters analyzed were moisture content, rehydration power, swelling power, and elasticity as well assensory. While the sensory data were examined by the Kruskal Wallis test. The physicochemical analysis properties test results showed that significant differences in rehydration power, swelling power, and water content, while the product elasticity showed no significant difference. The rehydration power, swelling power, elasticity,and water content showed that 86.67-133.34%;10-20%; 29.80-48.21% and1.19-1.95%, respectively. Furthermore, the sensory test results showed that there were significant differences in aroma and taste, while no significant differences in color and texture. The evaluation sensory of color and texture showed sig>α (0.88>0.05; 0.62>0.05), it mean that there was no difference, while in aroma and taste there were differences with sig<α (0.01<0.05). It can be concluded that the addition of soybean husk and carrot flour had an effect on the chemicals and organoleptic properties of dry noodle. To distguise the aroma of soybean husk other ingredients such as ginger or can be added. Hence,, the further research was necessary conducted in order to obtain strongly attractive color and aroma in dry noodle and to get rid of the unpleasant aroma optimally.
COVID-19防控中醫療衛生人員的責任衝突——儒家倫理的視角
Authors: 謝 廣寬 
Published: September 2023

LANGUAGE NOTE | Document text in Chinese; abstract also in English.
自2019年COVID-19疫情爆發以來，醫療衛生人員承擔 了繁重的疫情防控工作。在這些工作中，他們承擔了更多的責 任，有些責任是相互衝突的，如照護患者的責任與照顧家庭的 責任。本文根據對部分中國醫療衛生人員的訪談，結合國內外 發表的相關文獻，對疫情防控中醫護人員面臨的責任衝突進行 梳理，並從儒家倫理的視角進行評析。
During the COVID-19 pandemic, healthcare providers faced many challenges and were loaded with heavy psychological burdens. This paper focuses on a moral dilemma between the duty of healthcare providers and the overall well-being of the providers and their families during the medical crisis of the pandemic in Huhan, China. Based on interviews, the paper takes a Confucian perspective to explicate the duties and supererogatory acts of those who volunteered to help and the balance between the moral duties of loyalty and filial piety.
Comparison of disc-diffusion and disc-volatilization assays for determining the antimicrobial activity of Thymus vulgaris L. essential oil
Authors: Ignatiuk Katarzyna , Dzikon Ewelina , Hagdej Brygida , Slotwinska Weronika , Malm Maria , Ossowski Mateusz , Kasela Martyna 
Published: September 2023

Abstract
Essential oils (EOs), being mixtures of various natural compounds, constitute an attractive source of novel antimicrobial agents. Along with multiple studies concerning their rich biological activity, there are different methods allowing to determine both antimicrobial activity in direct contact, as well as through the activity of vapours. Thyme constitutes one of the most common aromatic herbs used for pharmaceutical, cosmetic and culinary purposes. The aim of the study was to compare the antibacterial activity of liquid and vapour phases of Thymus vulgaris L. essential oil (TEO) against most common pathogenic Gram-positive (Staphylococcus aureus ATCC 25913, Enterococcus faecalis ATCC 29212, Bacillus cereus ATCC 10876) and Gram-negative (Escherichia coli ATCC 25922, Salmonella typhimurium ATCC 14028, Pseudomonas aeruginosa ATCC 27853) microorganisms. To determine TEO antibacterial properties, two methods were used: disc-diffusion assay so as to test activity in direct contact; disc-volatilization assay so as to determine activity in gaseous contact.
Statistical analysis showed that Gram-positive bacteria were more sensitive to TEO vapours than Gram-negative (p=0.005), while in the case of disc-diffusion assay, no such differences were evident. Moreover, sensitivity towards TEO differed among Gram-positive bacteria in disc-diffusion (p=0.009) and disc-volatilization assay (p=0.001). Among Gram-negative rods, a statistically higher sensitivity regarding E. coli was noted when compared to S. typhimurium in both direct (p=0.011) and gaseous (p=0.006) TEO contact. No activity of TEO against P. aeruginosa was found.
As thyme essential oil exhibited significant antimicrobial activity against Gram-positive bacteria in gaseous contact, this justifies its use as an addition to inhalation agents to prevent or support the treatment of upper respiratory tract infections. Further studies should therefore apply other methods for determining the antibacterial activity of TEO vapours to assess the exact minimal concentration inhibiting bacterial growth.
Assessment of the potential role of Trefoil Factor-3 marker as a predictive marker of complication in splenectomized and non splenectomized patients with beta thalassemia major
Authors: Ali Hanaa Adday , Awad Ayat Saeed , Ali Rawaa Adday , Salah Muthana , Alrufaie Mohauman M. 
Published: September 2023

Abstract
The study’s goal is to appraise the immunological inflammatory marker Trefoil Factor 3, which interacts with thalassemia pathogenesis particularly following splenectomy, and may offer new therapy options for the illness and its repercussions.
This is a case-control study design that included 60 patients identified as β-thalassemia major as participators in this study, in addition to 30 seemingly healthy subjects with age and sex close to the patients group who served as a control group. The participants were distributed into four groups: control group, splenectomized patients, non-splenectomized patients, and total patients. Suitable statistical techniques were employed to investigate the results.
The study’s findings demonstrated that there was a significance increase in the serum levels of TFF3 when comparing between (splenectomized, non-splenectomized and total patients) with healthy group (322.16±51.241, p-value=0.01, 317.20±42.449, p-value=0.01, 320±46.6, p-value=0.01), vs (309.38±21.94), respectively. Moreover, a comparison between splenectomized and non-splenectomized showed a significantly decrease in TFF3 (322.16±51.241) vs (317.20±42.449), (p-value=0.043).The presented study also revealed significant positive correlation between TFF3 level with ferritin, iron, total iron binding capacity, transferrin saturation, transferrin, fasting serum glucose, insulin and homeostasis model assessment-insulin resistance. Furthermore, unsaturated iron binding capacity and homeostasis model assessment-beta found a significant negative correlation with TFF3 level.
High serum levels of TFF3 in beta thalassemia patients, especially in splenectomies patients, are downregulated by inflammatory cytokines, which are primarily regarded as traditional inflammatory cytokines and are related to insulin resistance. Hence, TFF3 level can serve as a potential predictive for the early detection of beta thalassemia in the development and progression of complications.
The Effects of Bifidobacterium animalis Subsp. Lactis and Vitamin D on Immunological Response Following Vaccination in Puppies
Authors: Saridag Gökhan , Erdogan Songul , Ozalp Tahir , Ural Kerem , Erdogan Hasan 
Published: September 2023

Abstract
This study aimed to determine the effects of oral application of Bifidobacterium animalis subsp. lactis and vitamin D on the immune response after vaccination in puppies. Crossbred dogs at the age of 55–65 days (n=21) of both sexes were grouped according to the application as follows: Group 1 - commercial polyvalent vaccine only (Vanguard 5L4, Zoetis); Group 2 -polyvalent vaccine and vitamin D; and Group 3 - polyvalent vaccine, B. animalis subsp. lactis, and vitamin D. The antibody titers, measured 3 weeks after the vaccination and after the 1st booster, demonstrated sufficient protective levels against the canine distemper virus but without significant difference between the groups when compare both values. No significant differences either, were observed in antibody titers against canine parvovirus after the initial vaccination. However, after the 1st booster, Group 2 samples showed significantly higher antibody titer value compared to the other groups (p<0.05). In conclusion, the dogs included in this study had an adequate antibody response to canine parvovirus and distemper viruses following the vaccination and 1st booster in all three groups of animals, and significant increasing of protective antibody titers against canine parvovirus virus the after the 1st booster in the group where B. animalis subsp. lactis was included.
Effect of Seminal Plasma Protein Fractions on Cooled Dog Semen Kinetics
Authors: Tsvetkov Tsvetan Stefanov , Daskalova Denica Boyanova 
Published: September 2023

Abstract
Semen cooling and cryopreservation have revolutionized the field of reproductive biotechnologies. However, challenges persist in maintaining sperm quality and viability during these processes. The unsatisfactory results and the main problems are associated with low quality, viability, morphological, structural, and DNA integrity, changes in plasma membrane, ability to interact with female tract and decrease in sperm fertilization potential. The objective of this study was to determine the effect of seminal plasma proteins with different molecular weights on the kinetic parameters of dog spermatozoa during cold storage at 4 °C. The proteins were isolated from the dogs’ seminal plasma ranging between 6-200 kDa, separated in four fractions. The ejaculates (n=15) were collected from 6 heathy dogs which were pooled. Spermatozoa were extended with Tris medium alone (control) or with addition of one of the isolated protein fractions, and were then incubated at 4 °C for 2 hours. Sperm incubated with seminal plasma proteins ranging between 10-15 kDa had significantly higher total motility (37.01±2.98%), sperm progressiveness (15.97±1.91%), curvilinear line velocity (37.46±3.75 μm/s), linearity (26.18±1.00%), and straightness (45.94±2.03%) compared to the other groups incubated with higher molecular weight proteins and the control group. The findings of this study indicated that the use of certain proteins in seminal plasma can be beneficial for reducing the detrimental effect of cooling at 4 °C and preserving the viability of dog spermatozoa. It seemed that the presence of 10-15 kDa proteins from canine seminal plasma rendered the spermatozoa less amenable to the negative influence during cooling.
First Report of Bartonella Henselae Infection in a Cat in North Macedonia
Authors: Shikoska Ivana , Djadjovski Igor , Krstevski Kiril , Hristovska Zagorka Popova , Janevski Aleksandar , Rashikj Ljubica , Cvetkovikj Aleksandar , Cvetkovikj Iskra 
Published: September 2023

Abstract
The genus Bartonella are fastidious, Gram-negative intracellular vector-borne bacteria with zoonotic potential. Cats have a crucial epidemiological role in the transmission of Bartonella henselae, the primary causal agent of cat-scratch disease in humans. Here we describe the first report of B. henselae infection in a cat in North Macedonia after a suspected Bartonella infection in a 7-year-old boy. A combination of cultural and molecular methods for detecting B. henselae in the asymptomatic cat was used. A blood sample was cultured on a blood agar plate, where colonies became visible after nine days of incubation. The DNA of a single colony was extracted, and the isolate was confirmed as B. henselae by sequencing the bacterial 16S ribosomal RNA gene and performing a Bartonella - specific PCR. The phylogenetic analysis demonstrated 100% similarity with B. henselae sequences, clustering on a single branch and establishing a distinct group. This finding indicates that B. henselae infection in cats circulates in North Macedonia and may affect feline and human health.
Low-dose interleukin-2 therapy in systemic lupus erythematosus
Authors: La Cava Antonio 
Published: September 2023

Abstract
In systemic lupus erythematosus (SLE), T regulatory cells (Tregs) contribute to the inhibition of autoimmune responses by suppressing self-reactive immune cells. Interleukin (IL)-2 plays an essential role in the generation, function and homeostasis of the Tregs and is reduced in SLE. Several clinical studies, including randomized trials, have shown that low-dose IL-2 therapy in SLE patients is safe and effective and can reduce disease manifestations. This review discusses the rationale for the use of low-dose IL-2 therapy in SLE, the clinical responses in patients, and the effects of this therapy on different types of T cells. Considerations are made on the current and future directions of use of low-dose IL-2 regimens in SLE.
Crecimiento económico en México: restricción por la balanza de pagos
Authors: Morones Carrillo Ana Lourdes 
Published: September 2023

El presente documento analiza el cumplimiento de la Ley de Thirlwall para México en el periodo 1993-2014. Se incluyen pruebas de raíz unitaria y cointegración que incorporan choques estructurales endógenos. El vector de cointegración en el contexto teórico sugiere una restricción al crecimiento de México por la balanza de pagos. La tasa de crecimiento del país en el periodo es mayor a la consistente con el equilibrio de balanza de pagos, lo que implica déficit comercial. Los resultados sugieren un cambio estructural de tal forma que se desincentiven las importaciones y se agregue mayor valor a las exportaciones.