bluuebunny/crossref_metadata_2025_split huggingface dataset:
Desarrollo del pensamiento crítico en estudiantes de Ingeniería mediante una estrategia didáctica que integra laboratorios remotos sobre circuitos eléctricos: primera intervención
Authors: Guerrero Zambrano Marcos , Concari Sonia Beatriz 
Published: December 2023

The objective of this research is to evaluate the effect of a didactic strategy that integrates remote laboratory practices on the subject of electrical circuits to promote the development of critical thinking in engineering students from a state university in Ecuador. It is design-based research that combines both quantitative and qualitative methodologies divided into two interventions; here we present the first intervention in which a teacher and 60 subjects between 18 and 20 years of age participated. The design of the didactic strategy included readings, open and closed questions and carrying out experimental practices with a remote laboratory. Two tests were applied to determine the levels of development of critical thinking and the level of learning achievement of the studied subjects: at the beginning, prior to the design and application of the strategy, as a diagnostic evaluation and at the end, after applying the didactic strategy. Comparing the results of both tests at the beginning and at the end of the application of the didactic strategy, it was found that 33 subjects increased their level of critical thinking by at least 1 point, a result validated with the Wilcoxon test, and 38 subjects increased their level of learning achievement by at least 1 point, a result validated through the Hake gain, which corresponds to 61 % and 63 % respectively of the total sample. As a result of the application of the didactic strategy, of the 60 subjects in the sample, 23 (38 %) significantly improved both the development of critical thinking and learning.
COMPLICATIONS OF MINIMALLY INVASIVE PERCUTANEOUS NEPHROLITHOTOMY IN THE TREATMENT OF KIDNEY STONES AT MILITARY HOSPITAL 103
Authors: Le Huy Ngoc , Tran Van Hinh , Pham Quang Vinh , Lanh My Duyen 
Published: December 2023

Objectives: To evaluate the complications of the minimally invasive percutaneous nephrolithotomy (mini-PCNL) in treating kidney stones at Military Hospital 103. Methods: A prospective, longitudinal study on 286 kidney stone patients operated using the mini-PCNL technique at Military Hospital 103 from July 2017 to July 2019. Results: After mini-PCNL, most patients had no complication (77.62%). Bleeding and fever after mini-PCNL were the two most common complications; there were 35 patients with intraoperative bleeding and no need for blood transfusion (12.24%) and 15 patients with fever after surgery and no chills (5.24%). The stone size affected its clearance rate but did not affect fever and bleeding after mini-PCNL. After mini-PCNL, the mean values of Red Blood Cell (RBC), Hemoglobin (HGB), and Hematocrit (HCT) decreased from 4.75 ± 0.53 T/L, 140.38 ± 15.38 g/L, and 0.42 ± 0.04 L/L to 4.25 ± 0.44 T/L, 125.05 ± 13.36 g/L, and 0.38 ± 0.04 L/L, respectively. Conclusion: After mini-PCNL, the complication rate was 22.38%. Bleeding and fever after mini-PCNL were the two most common complications, with 46 patients (16.08%) and 18 patients (6.29%), respectively. The residual stone fragments were 19.58%. The stone size affected its clearance rate but did not affect fever and bleeding after mini-PCNL
Assessment of Epizootic Ulcerative Syndrome (EUS) in Estuarine Fishes Collected from Arasalar Estuary, Puducherry State, India
Authors: Saravanan, S.  , Rajendiran, A.  , Sivakami R. 
Published: December 2023

Fishes form an important source of cheap protein for people of many countries. The majority of the global production comes from freshwater aquaculture (58%) followed by marine (36%) and brackish water (6%). With an average increase in aquaculture production of 11% during the last decade, aquaculture has become the fastest growing sector of the world food economy However, fish diseases is now posing a great threat to achieve maximum production and has become a limiting factor to the success of aquaculture. Among the various diseases, Epizootic Ulcerative Syndrome (EUS) is a disease affecting a wide range of wild and farmed freshwater and estuarine fish which has spread across south-east Asia and India. From the fish survey, Food Fishes were collected from the Arasalar estuary, Puducherry State, India. The fish caught were identified and average 200 species of each fish were examined for EUS (Epizootic ulcerative syndrome) infection for the four seasons of the year (Pre-summer, Summer, Post-summer and Rainy season). The results of the number of fishes with EUS that could be identified in the different seasons are reported. Of the 75 fishes, that were examined, 12 were affected with EUS. This shows that 16% of the fishes were subjected to infection.
Among Lizaparsia, 11 species were infected representing 14.6% of infection and among Mystus, seven fishes were infected forming 9.3% of infection. With regard to Oreochromis mossambicus, only four species were infected forming 5.3% of infection. With regard to Glossogobius giuris, nine species were infected thus 12% of infection. Nevertheless, during this period, the range of infection ranged from nil to 16%.
During the pre-summer season, the percentage of infection again ranged from nil but to 12%. The maximum infection was noticed in Liza parsia (9 fishes) representing 12% infection, Puntius filamentosus (8 fishes) recording 10.6% followed by Glossogobius and Mystus (8%) and Oreochromis mossambicus (1.33%) infection respectively. During the summer and the post-summer season, none of the fishes that were investigated recorded any signs of EUS. Thus, an overall comparison reveals that the highest percentage of EUS was recorded in the rainy season followed by the pre-summer season and least in summer and post-summer season.
DENTAL HEALTH OF AN ELDERLY PERSON WITH DIABETES MELLITUS: MYTH OR REALITY?
Authors: Иорданишвили А.К. 
Published: December 2023

Повышение качества стоматологического здоровья людей, страдающих сахарным диабетом, является актуальной задачей современной мировой медицины. Целью работы явилось улучшение показателей стоматологического здоровья пожилых людей, страдающих сахарным диабетом 2-го типа, путем совершенствования организационных форм оказания стоматологической помощи и применения отечественных средств индивидуального ухода за полостью рта. В ходе работы проведен анализ стоматологического здоровья 55 женщин пожилого возраста, страдающих сахарным диабетом 2-го типа, которые находились под динамическим наблюдением врача-стоматолога, а также 34 женщин этой же возрастной группы, страдающих сахарным диабетом 2-го типа, которые посещали врача-стоматолога по обращаемости. Показано, что у пожилых людей, страдающих сахарным диабетом 2-го типа, можно добиться хорошего стоматологического здоровья при их нахождении под динамическим наблюдением у врача-стоматолога при двукратном его посещении в течение года, при соблюдении адекватного ухода за полостью рта (с регулярным применением в домашних условиях отечественных средств). В подавляющем большинстве такие пожилые люди не нуждались в лечении патологии твердых тканей зубов (90,91%), имели хорошую индивидуальную гигиену полости рта (индекс гигиены — 0,88±0,24), ремиссию патологии тканей пародонта (87,27%) при удовлетворительном уровне стоматологической помощи (индекс УСП — 66,24%) в отличие от пожилых людей, страдающих сахарным диабетом 2-го типа и посещающих врача-стоматолога по обращаемости.
Improving the quality of dental health of people suffering from diabetes is an urgent task of modern world medicine. The aim of the work was to improve the dental health indicators of elderly people suffering from type 2 diabetes mellitus by improving the organizational forms of dental care and the use of domestic means of individual oral care. In the course of the work, an analysis of the dental health of 55 elderly women suffering from type 2 diabetes who were under the dynamic supervision of a dentist, as well as 34 women of the same age group suffering from type 2 diabetes who visited a dentist on the appeal was carried out. It is shown that in elderly people suffering from type 2 diabetes, it is possible to achieve good dental health when they are under the dynamic supervision of a dentist with a 2-fold visit during the year, adequately using oral care products. In the vast majority of such elderly people did not need treatment for pathology of hard dental tissues (90.91%), had good individual oral hygiene (hygiene index — 0.88 ± 0.24), remission of periodontal tissue pathology (87.27%) with a satisfactory level of dental care (USP index — 66.24%), unlike older people, suffering from type 2 diabetes mellitus, and visiting a dentist on appeal
LIFE-THREATENED ARRYTHMIA IN PATIENT WITH RHEUMATOID ARTRITIS AFTER COVID-19 INFECTION
Authors: Галенко А.С. , Исецкая А.О. , Ушаков В.А. , Паршков Е.Е. , Морозов А.Н. 
Published: December 2023

Несмотря на частое поражение сердечно-сосудистой системы при ревматоидном артрите, возникновение при этом иммуновоспалительном заболевании стойких желудочковых нарушений ритма нехарактерно. Однако инфекция SARS-CoV-2 изменила привычное течение многих заболеваний, вызывая ранее практически не встречающиеся жизнеугрожающие осложнения, что и продемонстрировано в данной статье.
Despite are frequent cardiovascular complications in rheumatoid arthritis, persistent ventricular tachycardia is uncommon. However, SARS-CoV-2 infection has changed the usual course of many diseases, so now we can face with previously almost non-existing life-threatening complications, which we have demonstrated in the article.
De la recherche à la production industrielle des produits de santé (Présentations d'expériences réussies) Expérience n°2 : PHYTOMED de la Côte d’Ivoire
Authors: KOUAKOU SIRANSY Gisèle 
Published: December 2023

Contexte : Le développement de phytomédicaments ou médicaments traditionnels améliorés en Afrique sub-saharienne connait un succès grandissant. En Côte d’Ivoire, diverses unités artisanales de fabrication de phytomédicaments se développent mais restent peu évalués pour leur efficacité, innocuité et qualité.
Justificatif : Parmi toutes les pathologies affectant la population subsaharienne, le paludisme occupe une place importante étant la première cause de maladie infectieuse parasitaire, et la 3ème cause de maladies infectieuses. Les produits de santé des tradithérapeutes restent peu évalués pour leur efficacité, innocuité et qualité. Les chercheurs et enseignants chercheurs au sein des universités ont emboîté le pas dans plusieurs pays. En Côte d’Ivoire aucune université n’a franchi le pas de la production à l’échelle d’unité industrielle pilote.
Objectif : L’objectif de ce travail visait à sélectionner des plantes pour la mise au point de phytomédicaments antipaludiques de qualité de catégorie 2 OMS.
Méthodologie : La sélection des plantes à l’essai a concerné celles ayant fait l’objet de travaux de recherche des Universités en Côte d’Ivoire. Parmi ces derniers, ceux évaluant l’effet sur des extraits aqueux de parties aériennes des plantes. De ces extraits ceux présentant les meilleures inhibitions de croissance du Plasmodium selon les critères de Wilcox, ont été retenues pour la mise au point de phytomédicaments de catégorie 2 OMS. Les essais de pré formulation er formulation galénique à l’échelle de laboratoire ont permis de mettre en œuvre le procédé de fabrication adéquat. Une transposition à l’échelle pilote a été ensuite réalisée pour démontrer la reproductibilité de la fabrication industrielle de la forme galénique mise au point.

Résultats : Ces résultats issus des travaux de chercheurs des universités ivoiriennes ont permis de recenser 58 plantes médicinales étudiées pour leur activité antiplasmodiale depuis 1996. Parmi ces plantes 38 ont fait l’objet d’extraits aqueux, décoctés ou infusés. Sept extraits aqueux présentant de CI50
<5µg/ml ont été retenues entre autres. Cependant la majorité des études scientifiques portant sur les plantes médicinales potentiellement antipaludiques ont été réalisées dans des modèles in vitro, rare sont celle réalisés in vivo, dans des modèles murins. Les résultats des essais pharmacologiques, de formulation et de transposition à l’échelle pilote ont permis de disposer de gélules à base de granulés de plantes issus d’une granulation humide.
Conclusion : Les travaux scientifiques des Universités de Côte d’Ivoire offre un large éventail de plantes médicinales à potentiel antimalarial pour la conception de phytomédicaments de qualité de catégorie 2 OMS. Des essais préliminaires réalisés in vivo ont permis d’obtenir un brevet d’invention.
De la recherche à la production industrielle des produits de santé (Présentations d'expériences réussies) - Expérience n°5 : Développement de MelaK@ crème pour le traitement des brûlures chez l’enfant (Expérience du CEA-CFOREM)
Authors: SEMDE Rasmané 
Published: December 2023

Pr. Rasmané Semdé, CEA-CFOREM, École doctorale sciences et santé (ED2S), UFR - Sciences de la santé (UFR/SDS), Université Joseph KI-ZERBO, 03 BP 7021 Ouagadougou, Burkina Faso
Les brûlures cutanées figurent parmi les problèmes de santé majeurs en Afrique, avec plus de 17 millions de victimes chaque année. Au Burkina Faso, l’incidence est en croissance avec 13,7% des enfants de moins de 5 ans. La prise en charge précoce et appropriée aide à minimiser la douleur, à prévenir les complications et à favoriser une guérison rapide. Elle peut nécessiter une urgence médico-chirurgicale, une réanimation ou juste un traitement local utilisant des produits importés sont souvent financièrement inaccessibles aux populations africaines.
MelaK@ crème est une émulsion Huile dans Eau constituée du miel et du beurre de karité, fournis à des prix abordables par des producteurs sélectionnés du Burkina Faso. Elle visait à créer un effet synergique entre les propriétés anti-inflammatoire, cicatrisante et antimicrobienne du miel et celles régénératrice et photoprotectrice du beurre de karité. Le travail de développement a permis d’obtenir un produit d’application aisée, homogène et stable sous certaines conditions de conservation. Après avoir démontré son efficacité comparée aux traitements modernes conventionnels par des tests in vivo sur des rats de laboratoire, puis confirmée par une étude clinique en 2020chez des brulés de 2nd degré, l’émulsion a été brevetée à l’Organisation Africaine de la Propriété intellectuelle (OAPI) le 13/07/2020, sous le N°19447.
MelaK@ crème est présentée dans des tubes en aluminium verni de 45 g et de 75 g pour application locale destinés aux traitements des brûlures. Demandée comme préparation magistrale à travers les officines pharmaceutiques privées par les chirurgiens pédiatres des CHU du Burkina Faso, plus de 1500 tubes préparés à l’échelle du laboratoire ont déjà permis de traiter plus de 250 enfants brulés. Face à la demande croissante des praticiens hospitaliers et du grand public, un business plan démontre sa rentabilité, le dossier de demande d’AMM d’un médicament traditionnel amélioré (MTA) de catégorie II a déjà été déposé à l’ANRP du Burkina Faso.
Antiviral Targets and Known Antivirals (HAART)
Authors: Helen Ifedilichukwu Nma , Joy Oladimeji-Salami 
Published: December 2023

In 2021, the number of HIV-positive people worldwide was estimated to be 38.4 million. Since its discovery four decades ago, the scope of the HIV infection has outstripped all predictions, necessitating the urgent need to develop novel antivirals against the virus that target crucial stages in the virus’ life cycle. New antiviral drug classes that were developed in response to the HIV epidemic were coupled to offer very highly active antiretroviral treatment. These novel highly active antiretroviral therapies (HAART) were developed as a result of the emergence of drug-resistant strains of the virus. By inhibiting these enzymes, reverse transcriptase, integrase, and protease that are essential for viral attachment, entry, integration, and maturation, antiretroviral therapy (ART) strategies can suppress the virus, lower the viral load, boost CD4 count, and ultimately halt the progression of the disease. Advances in research on the biology of both the immature and the mature forms of the HIV capsid in terms of its structure and function have made it possible to discover and/or design small molecules and peptides that interfere with the virus’s assembly and maturation. This article presents and reviews HAART’s current state and strategies as a very active antiviral.
The Effect of Liquid Fermented Potato Hash Diet on Testicular Size, Weight and Epididymal Semen Quality of Large White × Landrace Boars
Authors: Richard Netshirovha Thivhilaheli , Constance Raphalalani Zwivhuya , Lottus Mphaphathi Masindi , Tsatsimpe Mammikele , Deirdre Sehlabela Lerato , Sebothoma Pulane 
Published: December 2023

The study aimed to evaluate testicular size, weight and epididymal semen quality of Large White × Landrace (LW × LR) boars fed fermented liquid potato hash. Diets containing either 200 (LFLPH) g/kg potato hash; 400 (HFLPH) g/kg potato hash or no fermented potato hash (control). Forty-two crossbred boars (LW × LR) weighing (25 ± 2.3 kg) were individually housed and fed ad-lib one of the seven dietary treatments for three months. Pigs were allocated to diets in complete randomized design. After 3 months and 600 ± 4 kg average body weight boars were slaughtered and epididymal semen was collected from head of epididymis. Boars that were fed control had higher (P < 0.05) live spermatozoa concentration than LLFPH and HFLPH diets. However, HLFPH had higher (P < 0.05) proximal droplet, distal droplet and dead spermatozoa concentration than control and LLFLPH. In addition, boars that were fed control and LLFPH had higher (P < 0.05) total, progressive, rapid motility, and lower non-progressive, static, medium and slow motility than HLFPH. It is concluded that low liquid fermented potato hash diet could be used as an alternative feed source for pigs. The results indicated that diets contain LFLPH can be used in boar diets without any adverse effects on spermatozoa quality.
Archaeometric characterization of chlorite-based manufacturing waste from workshop areas of the Konar Sandal South Complex, Jiroft (Kerman, Iran, 3rd millennium BCE)
Authors: SHAFIEE Mojgan , COLETTI Chiara , FAZELI NASHLI Hassan , ESKANDARI Nasir , VIDALE Massimo , MARITAN Lara 
Published: December 2023

Sixteen small samples of fragmentary “chlorite” containers, coming from three different workshop sites of the Konar Sandal South network (Iran), were analyzed using a multianalytical approach, consisting in thin-section petrography and mineralogical characterization by X-ray powder diffraction. This preliminary study singled out at least two major different mineralogical groups, suggesting that different craft groups, possibly in different times, exploited different local sources of chloritic rocks. Results also indicates that the surroundings of Konar Sandal South, the main urban hub of the Halil valley, were involved – probably for several centuries – in the production of three major different classes of stone pots (cylindrical vessels with intricate geometric patterns, plain bell-shaped bowls and incised série récente vessels).
Pengaruh Good Corporate Governance Terhadap Pengungkapan ESG dan Kinerja Perusahaan Pada Perusahaan BUMN yang Terdaftar di Bursa Efek Indonesia Periode 2018-2022
Authors: Asmaul Husna Gempita , Yuhertiana Indrawati , Susilowati Endah 
Published: December 2023

Latar Belakang: Wujud komitmen perusahaan terhadap isu keberlanjutan adalah dengan melaksanakan tangung jawab yang berkaitan dengan sosial, lingkungan, dan tata kelola sehingga dengan demikian perusahaan bertanggung jawab dalam mewujudkan pembangunan yang berkelanjutan sesuai dengan komitmen negara-negara G20 terhadap isu SDGs (Sustainable Development Goals).
Tujuan: Tujuan dari penelitian ini adalah untuk mengukur pengaruh Good Corporate Governance terhadap pengungkapan ESG dan Kinerja Perusahaan pada Perusahaan BUMN yang terdaftar di BEI periode 2018-2022.
Metode: Metode penelitian yang digunakan dalam penelitian ini adalah pendekatan kuantitatif. Data pengungkapan ESG yang digunakan dalam penelitian ini berasal dari laporan keuangan dan laporan SR yang ada di BESI dalam kurun waktu lima tahun, dari tahun 2018-2022 dengan menggunakan alat uji statistic SmartPLS.
Hasil: Berdasarkan hasil penelitian dapat disimpulkan bahwa ukuran dewan direksi, independensi komite audit, jumlah rapat komite audit, tidak berpengaruh terhadap Pengungkapan ESG. Jumlah rapat dewan direksi, ukuran komite audit, keahlian komite audit berpengaruh terhadap pengungkapan ESG.
Kesimpulan: Ukuran dewan direksi, independensi komite audit, jumlah rapat komite audit tidak berpengaruh dengan kinerja perusahaan. Jumlah rapat dewan direksi, ukuran komite audit, dan keahlian komite audit berpengaruh terhadap kinerja perusahaan
Analysing entropy generation of MHD (50:50) slip flow over an inclined needle
Authors: Priya Selvaraj , Rajamani Gundada Raju , Ganga Bhose , Hakeem Abdul Kaffoor Abdul , Ragupathi Pachiyappan 
Published: December 2023

The primary objective of this study is to quantify the rate of entropy generation within the magnetohydrodynamic (MHD) slip flow system over the inclined needle. Entropy generation is a measure of the irreversibility and inefficiency in the flow process. The slip flow condition at the fluid interface can significantly impact the flow characteristics and heat transfer rates. In the hybrid nanofluid flow, which consists of non-magnetic and magnetic (Al2O3 and Fe3O4) nanoparticles, H2O+C2H6O2 (50:50) are considered as the base fluid. Furthermore, the effects of inclined magnetic fields are taken into interpretation. The PDE’s governing equations are converted into ODE’s using similarity transformations and solved by a numerical technique based on BVP4C. The results illustrate that crucial parameters such as the magnetic parameter, mixed convection parameter, nanoparticles of solid volume fractions, and Prandtl numbers are pointedly impacted by momentum and thermal profiles. The entropy and Bejan number also consider being various relationship-combined parameters. These analyses protest that raising the magnetic parameter estates an increase in the hybrid nanofluid thermal profile under slip circumstances. Examined magnetic field impact on flow and entropy generation in MHD flows, revealing significant changes in entropy generation due to interaction between magnetic field and nanoparticles. This analysis understands the impact of MHD and slip effects on entropy generation, particularly in the context of the newly emerging 50:50 fluid mixture. Hybrid nanofluids have been shown to have improved thermal conductivity compared to traditional fluids, which can enhance the cooling or heating capabilities of the inclined needle.