bluuebunny/crossref_metadata_2025_split huggingface dataset:
Influence of Immediate and Delayed Dentin Sealing on Bonding Strength of Lithium Disilicate Glass Ceramic: An in vitro Study
Authors: Darweesh Rami , Al-Zahawi Abdulsalam 
Published: December 2023

Objective: To investigate the influence of immediate and delayed dentin sealing technique on shear bonding strength (SBS) of the lithium disilicate glass-ceramic on tooth structure with different depths. Methods: The buccal surfaces of 40 maxillary first premolars were prepared with two different depths (1mm and 1.5 mm) and two different timings for bonding (immediate and delayed dentin sealing). G1 (1 mm preparation) and G2 (1.5 mm preparation) were treated with bonding (Tetric N-Bond Universal, Ivoclar,2021, Schaan/Liechtenstein) two weeks after preparation, before cementation to the ceramic block with delayed dentin sealing (DDS), while G3 (1 mm preparation) and G4 (1.5 mm preparation) were treated immediately after preparation with bonding and immediate dentin sealing (IDS). All specimens were stored in artificial saliva (Biotene dry mouth, GSK goupe, Canada) for two weeks at 24℃. Forty lithium disilicate glass-ceramic rectangular blocks (Rosetta SM) (HASSBIO, Korea) with dimensions of (2 mm height, 2mm width and 3 mm thickness) were prepared. After preparation of the tooth surfaces, all prepared blocks were cemented to the prepared teeth in groups GI and G2 with phosphoric acid 37% for 15 seconds, and all ceramic fitting surfaces were treated with 10% hydroflouric acid for 20 seconds and coupling agent monobond, then aging was performed for 5000 cycles in artificial saliva from 5-55 °C for all specimens. A universal test machine was used to test the shear bond strength (SBS). The statistical analysis was done using a one-way ANOVA test followed by Tukey's post hoc test (p<0.05). Results: The result revealed that IDS and minimum preparation depth had significantly higher bonding strength than DDS. Bonding strength in sequence was 15.50 ± 3.873 MPa in G3 and G4 8.25 ± 3.344 MPa, while for delayed dentin sealing the bonding strength was 7.75 ± 2.993 in G1 and 6.25 ± 2.125 MPa in G2. Conclusions: Teeth treated with IDS immediately after preparation showed significantly higher bonding strength than those treated with DDS for indirect ceramic restoration. Also, increase in the depth of the preparation toward the dentin led to a decrease in the bonding strength of the restoration.
A rare case of nulliparous prolapse at term
Authors: Phool Divya , Kaur Khushpreet , Pandove Arti , Jindal Ruchi 
Published: December 2023

Uterovaginal prolapse complicating pregnancy is an extremely rare event. Obstetricians should be familiar with the condition as early recognition and close follow up is essential in order to avoid possible fetomaternal risks. Its incidence is higher in women of advanced age and parity. This case report presents a rare occurrence of prolapse in nulliparous woman. In the present case report, we describe a case of a 24 year-old nulliparous female who experienced sudden uterine prolapse at 38 weeks of gestation without labor. She was delivered by cesarean section in view of primi with breech. Following delivery, the prolapse promptly improved and did not recur.
A rare location of the rare tumour-chondromyxoid fibroma of calcaneum
Authors: Rajpurohit Narendrasinh , Shariff Fardeen 
Published: December 2023

Chondromyxoid fibroma (CMF) primary location is the long tubular bones of the lower extremity followed by foot and knee. This benign cartilaginous tumor of bone is the rarest reported neoplasm of cartilaginous origin. This mass can mimic other benign and malignant bone tumors owing to its variable histologic features. We report a case of CMF of the calcaneum with varying presentations. Pathologic examination is difficult but can be used to differentiate this lesion from more serious conditions. A quick and accurate diagnosis of CMF can prevent unnecessary treatment that could be harmful to the patient.
A study of stages and supplementary issues of Parkinson\'s in Parkinson disease and movement disorders
Authors: Raju V Rama , Lavanya N , Premchand P 
Published: December 2023

: Indorsing (endorsing or encouraging) participation plus autonomy (PA) within the people has been tinted or emphasized as an definitive goal-of-rehabilitation for subjects with constant disorders and/or diseases by the World Health Organization (WHO), yet there are insufficient studies concentrating over the “PA” within the subjects through the Parkinson disease (PD). Thus, we present this study objectives to clarify/explain (explicate) the degree of “PA “within the Palasioses’ve the psychosomatic also developmental(behavioral) causes linked through it. : Subjects were inducted as of the neurology of a tertiary care hospital and city neuro research center by applying ease sampling for this type of research study design. A survey casing or layering the societal-demographic, illness-linked typical, Bharat version of impact over the involvement and participation autonomy (“IPA”) survey, and other rating scales including H and Y staging system plus all time UPDRS considering the UK brain bank criteria were employed. A statistical multi latent-variate stepwise linear regression analysis-technique was applied to decide the features/ (factors) which influences IPA. : Regression showed UPDRS-stage III, β=0.34, p&#60;0.001, chi-square, with 2 degree of freedom, highly significant had very good correlation by IPA, followed by drive (i.e., tenacity) as the second robust feature β=-0.24, p&#60; 0.001. Also, H and Y score β=0.18, p&#60; 0.001, plus accessibility-of- community sustain β=-0.11, p =0.001 were great factors. : Standard echelon of PA amid Parkinson`s was middle (worse). Their bodily function, `psychological-resilience` plus `social-support` were the best factors coupled through PA amongst Parkinson`s. Thus the results yield significant insights in to Parkinson`s `PA` which aid clinicians for determining/predicting early-risks of limited PA amid Parkinson`s, executing involvement to endorse, to advance-PA and lastly to complete the decisive therapeutic-treatment.
A comparative evaluation of microsurgical excision of olfactory groove meningioma through unilateral (pterional) vs Bilateral (Bifrontal-transbasal) approach
Authors: Singh Deepak Kumar , Mishra Vineet Kumar , Chand Vipin Kumar , Singh Neha , Gupta Amit 
Published: December 2023

Surgical management of olfactory groove meningiomas poses significant challenges. Common microsurgical approaches often result in delayed exposure of neurovascular structures. In contrast, the pterional approach offers the advantage of early dissection of the posterior neurovascular complex. Olfactory groove meningiomas constitute 4 to 13% of all meningiomas. Surgery is the primary treatment, but the recommended extent and types of approaches vary. We conducted a retrospective review of our olfactory groove meningioma series treated with microsurgery via standard unilateral or bilateral approaches. Patient records from our department (RMLIMS, LUCKNOW) were reviewed, encompassing cases treated with unilateral or bilateral approaches. Thirty patients who underwent olfactory groove meningioma removal were included, and clinical data, radiological findings, surgical treatment, and clinical outcomes were retrospectively analyzed. A total of 30 craniotomies were performed, with 16 employing unilateral pterional approaches and 14 using bilateral transbasal approaches. Overall, gross total tumor resection was achieved in 27 cases. Postoperative complications included edema (in three patients) and hematoma (in three patients). The unilateral (pterional) approach emerges as an excellent solution for olfactory groove meningioma treatment, offering early visualization of the posterior neurovascular complex. Additionally, it enables frontal sinus preservation and minimizes excessive brain retraction.
Survival and analysis of patients with various central nervous tumors who received post-operative radiation therapy: A retrospective study
Authors: Bhandari Virendra , Singhal Saloni , Lodi Ashar , Kumar Amresh 
Published: December 2023

Central Nervous Tumors constitute 3% of cancer cases worldwide. The incidence of CNS tumors in India ranges from 5-10 per 100,000 population, ranking 14 among all other tumors and accounting for 2% of all malignancies. The five most frequent tumors are astrocytoma (47.3%), Medulloblastoma (11.4%), craniopharyngioma (9.7%), ependymal tumors (4.8%), and nerve sheath tumors (4.1%). The tumor spectrum varies among different ages and sexes. The medical records of 238 patients were evaluated, out of which only 102 were fit for the study as per the inclusion and exclusion criteria. The 3-year median overall survival (OS) of 8 years and Progression Free Survival (PFS) of 7 years, while the 5-year median OS of 9 years and PFS of 7 years is recorded. Glioblastoma (GBM) is the most aggressive out of all histologies, with a 2-year survival of 31% and a median OS of 8 months, as per our study. We got some good results with brainstem glioma as well, with a 2-year survival of 40% and a median OS of 18 months. The survival in CNS tumours has improved widely with adjuvant concurrent chemotherapy with temozolamide along with radiation postoperatively and then adjuvant for 6months to 1 year and it was also seen that more complete the tumour resection done, the better was the survival seen.
Diagnostic concordance in consultation liaison psychiatry – Referring physicians to psychiatrists
Authors: Benerji Therissa , Bodepudi Sarath , Cherukuri Gayathri Devi , Kodali Madhavi , Parvathaneni Krishna Mohan 
Published: December 2023

Psychiatric co-morbidity in patients with physical illness is known to influence the course and outcome of both conditions. Consultation liaison psychiatry [CLP] can be regarded as an essential service between psychiatry and other medical specialties. Efficient communication between different levels of care is known to have an impact on the quality of health care. To study the patterns of referrals to the department of psychiatry and diagnostic concordance between referring physicians to CL-Psychiatrist.The present study was a cross-sectional study conducted in the Department of Psychiatry of a tertiary care hospital. All the patients referred to the Psychiatry department for 4 months were taken after excluding referrals sent for disability assessment. Socio-demographic details, source of referral, reason for referral, and the psychiatric diagnosis by both the referring doctor and CL-psychiatrist were recorded. Statistical analysis was done using SPSS 25.0 software and kappa value was used to estimate the diagnostic concordance.In the sample of 100 referrals studied, the mean age of the sample was 40.96±13.42 years. The majority of the cases referred were inpatients (61%), from the department of general medicine and allied branches (85%), (General medicine -55, Neurology- 21). The most common diagnosis was alcohol dependence syndrome 24 (24%), followed by depression (18%) and phobic anxiety (18%).The concordance of the diagnosis between the referral and the psychiatry team was in perfect agreement (κ=0.81- 1.00) for paranoid schizophrenia, bipolar affective disorder, delirium, dissociative disorder, delusional disorder, and alcohol dependence syndrome. Very low concordance was observed in diagnosing obsessive-compulsive disorder (k=0) and adjustment disorder (k=0).The overall diagnostic concordance was poor for adjustment disorder, OCD, and vascular dementia, and good for paranoid schizophrenia, delirium, dissociative disorder, delusional disorder, and BPAD.
Dichotomous interpretations and a stroke of luck: A case of silent cerebral hemorrhage
Authors: Paul Ankan , Tripathi Utkarsh K , Kaur Simranjit , Chakladar Abhishek , Alphonse Alexander M. 
Published: December 2023

“Silent Cerebral Hemorrhage” in a young alcohol-dependent individual can pose a significant challenge to the treating physician. The neuroimaging and clinical presentation maybe dichotomous to a critical extent.Our aim was to explore the scientific understanding of “Silent Cerebral Hemorrhage” and share the wisdom gathered about the diagnosis and management of this rare entity. A 32-year-old male presented with fever and episodes of vomiting alongwith urinary incontinence, in the backdrop of heavy alcohol abuse. Detailed neurological assessment revealed no abnormal findings. MMSE indicated towards no significant cognitive deficits. On MRI, an extensive intracerebral hemorrhage was observed.The I.C.H. score was 2/6 and the FUNC score was 8/11; which was in stark contrast to NIH Stroke Scale score of 0/42.Blood-panel showed deranged liver enzymes. Patient was managed conservatively. Irritability was controlled using Haloperidol. Prophylactic antiepileptics were also started.Upon follow-up, patient showed drastic improvement. Patient was started on Acamprosate for maintenance of abstinence.Through this case report we have tried to highlight that “Silent Cerebral Hemorrhage” can present as a curve-ball for clinicians and psychiatrists. The dichotomy in interpretation of stroke-related scales may cause a dilemma about the course of management.“In this case, the absence of neurological deficits was indeed a stroke of luck for the patient.”: “Silent Cerebral Hemorrhage” can present as a curve-ball for clinicians and psychiatrists. Hence, we should be vigilant about it in our clinical practice. The dichotomy in interpretation of stroke-related scales may cause a dilemma about the course of management.
Design and fabrication of a system to capture ambient CO2
Authors: Khan Sagir , Navalgund Lokeshwari , Joshi Keshava , Kumar Abhishek 
Published: December 2023

Introduction:In the coming decades, addressing climate change necessitates substantial Carbon dioxide (CO2) emission reductions. Carbon capture and storage are vital for achieving these goals. Beyond industrial emissions, Direct Air Capture (DAC) extracts CO2 from the atmosphere, complementing point source capture and enabling the reduction of atmospheric CO2 concentrations. Our research confirms the thermodynamic feasibility of DAC with Potassium hydroxide (KOH) solution, taking into account energy and performance considerations.
Materials and methods: To assess DAC's potential, we built a 1.2 m contactor prototype measuring CO2 absorption from the air. Operating at 100 pa with an air speed of 1.75 m/s in a cross-flow regime, we used KOH and NaOH solutions as capture mediums, implementing duty cycles for absorbent pumping and exhaust fan operation.
Results: Our findings revealed that transitioning to intermittent operation can dramatically reduce overall energy costs by 70%. We explored various absorbent concentrations for both KOH and NaOH solutions, examining their impact. Operating temperatures ranged from 14°C to 33°C, providing insights into temperature's pivotal role in DAC performance.
Conclusion: This study showcases the viability of DAC with a KOH solution, particularly highlighting the significant energy savings achieved through intermittent operation. These findings emphasise DAC's role as a vital tool in our collective efforts to combat climate change.
Finding New VEGFR2 Inhibitors Using Support Vector Machine Classification Model
Authors: Arabi Nooshin , Torabi Mohammad Reza , Fassihi Afshin , Ghasemi Fahimeh 
Published: December 2023

Introduction: In our current era, the prevalence of cancer and its associated mortality rates have become a pressing concern. As such, finding effective methods for treating cancer has become a matter of significant importance. Abnormal angiogenesis is one of the common characteristics of different types of cancer. So far, the inhibition of vascular endothelial growth factor receptor 2 signaling pathway has received much attention due to its pro-angiogenic role. Therefore, finding reliable computational models to identify inhibitors can be effective in reducing time and cost. The purpose of this study was to use the support vector machine method to classify compounds into two inhibitory and non-inhibitory groups.
Methods: In order to implement the machine learning model, the ligands studied in this research were extracted from the https://www.bindingdb.org database and after passing the necessary pre-processing, some filter-based and embedded feature selection methods were used. After extracting the descriptors from the data, using the feature selection algorithm based on correlation, the dimensions of the data have been reduced in order to avoid overfitting the model. The classification task utilized a support vector machine model, employing various kernels such as Radial Basis Function (RBF), Polynomial, Sigmoid, and Linear.
Results: The implementation of the support vector machine model with the RBF kernel along with the feature selection method based on correlation has resulted in a higher accuracy of 82.4% (P=0.008) compared to other feature selection methods used in this study.
Conclusion: Observations indicate that the correlation-based feature selection method is more accurate than other methods used in this study.
Проектирование системы эффективного управления молодёжной миграцией на основе методологии функционально-ориентированного моделирования (на примере Омской области) (в печати)
Authors: Мухаметдинова Светлана 
Published: December 2023

Актуальность. Миграционный отток населения в последнее десятилетие является одной из актуальнейших проблем Омского региона, от решения которой в значительной зависит социально-экономическое благополучие области. Значительную часть исходящего миграционного потока составляют выпускники общеобразовательных средних школ, которые стремятся получить престижное образование в столичных вузах и обеспечить себе в дальнейшем более качественный уровень жизни. Все попытки переломить негативную ситуацию в сфере миграции на протяжении длительного периода времени не привели к желаемому результату. Одной из причин такого положения дел является отсутствие масштабных комплексных научных исследований проблемной области, результаты которых могли бы стать основой эффективной стратегии управления миграционными процессами. Цель: выявить социально-экономические факторы, влияющие на интенсивность миграционных потоков на основе результатов опроса старшеклассников общеобразовательных средних школ г. Омска и спроектировать систему эффективного управления молодежной миграцией с использованием методологии функционально-ориентированного моделирования (на примере Омского региона). Методы: контент-анализ, синтез, классификация и обобщение, социологический опрос, функционально-ориентированного моделирование. Результаты: на основе анализа данных, полученных в ходе исследования, были выявлены социально-экономические факторы, оказывающее влияние на интенсивность исходящих миграционных потоков и спроектирована система эффективного управления молодежной миграцией с использованием методологии функционально-ориентированного моделирования (на примере Омской области), которая может быть использована в процессе разработки региональной стратегии в сфере миграции. Выводы: миграция представляетсобой сложную проблемную область, на которую оказывает влияние система взаимосвязанных социально-экономических факторов и результативность управления ею предполагает наличие научно-обоснованной стратегии. Одним из подходов к проектированию системы эффективного управления молодежной миграцией является методология функционально-ориентированного моделирования (на примере Омского региона), позволяющая визуализировать факторы, влияющие на интенсивность миграционных процессов, с учетом взаимосвязей между ними.
В поисках новых подходов к оценке благополучия в умных городах (в печати)
Authors: Колобашкина Татьяна 
Published: December 2023

Череда социально-экономических кризисов последнего времени актуализировано внимание исследователей и политиков к теме благополучия. Актуальность статьи обусловлена появлением новых вызовов, связанных со стремительным развитием технологической и цифровой среды мировых городов, несущей как как новые возможности, так и риски для человека. С одной стороны, цифровизация позволяет повысить доступность, качество и объем муниципальных услуг для горожан и, соответственно, положительно влияет на уровень благополучия горожан. ИКТ инструменты гибко, оперативно и мобильно позволяют адаптировать городскую среду под меняющиеся потребности наиболее активной части городского населения как драйвера развития территории, отслеживать и корректировать уровень благополучия человека в городcкой среде. С другой стороны, не решенной пока остается проблема растущего цифрового развития, технологической уязвимости, особенно в условиях растущей внешней конкуренции и санкций, нехватки цифровых компетенций у некоторых социальных категорий горожан, психологические проблемы социальной фрустрации, изолированности, разобщенности, ослабления социальных контактов, в том числе внутрисемейных и др. Цель: обзор существующих подходов к оценке городского развития и обоснование необходимости выработки нового подхода к оценке благополучия в цифровой среде умных городов. В качестве основного используется метод сравнения. В статье поведен анализ понятий «умный город», «умная нация», «умное общество». Проанализированы опыт и перспективы разработки подходов к оценке благополучия в городской среде, включая существующие глобальные и национальные индексы и рейтинги (Индекс городского процветания ООН, Индекс городской жизни, Индекс «IQ городов», Рейтинги устойчивого развития регионов и городов, Индекс умных городов, Индекс «Город в движении», Индекс качества жизни населения, основанный на структуре ценностей города/горожан, Индекс городской успешности, Индекс культурного капитала городов, Рейтинг инновационной привлекательности мировых городов и др.). Полученные результаты позволяют сделать выводы о преобладающем внимании к технологической составляющей и недостаточном внимании к социальным и психологическим аспектам усиливающейся урбанизации и цифровизации, необходимости перехода от концепции «умного города» к концепциям «умного общества» и «умного городского управления». Подчеркнута необходимость сопряжения подходов, связанных с использованием человекосберегающих и цифровых технологий, особенно в условиях преодоления опыта пандемии Covid-19. Сделан ключевой вывод, что комплексный подход к оценке благополучия человека в цифровой среде умных городов еще предстоит выработать, в том числе перспективным направлением дальнейшего развития походов к оценке благополучия в городах с перспективой локализации разрабатываемых рейтингов и индексов является сотрудничество в рамках ЕАЭС и БРИКС. На решение этой задачи будет направлена работа создаваемого межвузовского консорциума «Благополучие человека в цифровой среде умных городов».