bluuebunny/crossref_metadata_2025_split huggingface dataset:
1. Lumbosacral radicular pain
Authors: Peene Laurens , Cohen Steven P. , Kallewaard Jan Willem , Wolff Andre , Huygen Frank , Gaag Antal van de , Monique Steegers , Vissers Kris , Gilligan Chris , Van Zundert Jan , Van Boxem Koen 
Published: November 2023

AbstractIntroductionPatients suffering lumbosacral radicular pain report radiating pain in one or more lumbar or sacral dermatomes. In the general population, low back pain with leg pain extending below the knee has an annual prevalence that varies from 9.9% to 25%.MethodsThe literature on the diagnosis and treatment of lumbosacral radicular pain was reviewed and summarized.ResultsAlthough a patient's history, the pain distribution pattern, and clinical examination may yield a presumptive diagnosis of lumbosacral radicular pain, additional clinical tests may be required. Medical imaging studies can demonstrate or exclude specific underlying pathologies and identify nerve root irritation, while selective diagnostic nerve root blocks can be used to confirm the affected level(s).In subacute lumbosacral radicular pain, transforaminal corticosteroid administration provides short‐term pain relief and improves mobility. In chronic lumbosacral radicular pain, pulsed radiofrequency (PRF) treatment adjacent to the spinal ganglion (DRG) can provide pain relief for a longer period in well‐selected patients. In cases of refractory pain, epidural adhesiolysis and spinal cord stimulation can be considered in experienced centers.ConclusionsThe diagnosis of lumbosacral radicular pain is based on a combination of history, clinical examination, and additional investigations. Epidural steroids can be considered for subacute lumbosacral radicular pain. In chronic lumbosacral radicular pain, PRF adjacent to the DRG is recommended. SCS and epidural adhesiolysis can be considered for cases of refractory pain in specialized centers.
Disaster preparedness perception, pyschological resiliences and empathy levels of nurses after 2023 Great Turkiye earthquake: Are nurses prepared for disasters: A risk management study
Authors: Ediz Çiçek , Yanik Derya 
Published: November 2023

AbstractObjectiveThe purpose of the study is to determine the disaster preparedness perceptions, psychological resilences and empathy levels of nurses after 2023 Great Turkiye Earthquake.MethodThis descriptive study was conducted in 2023 using with E‐Anket. This study was carried out with voluntary participation of 464 nurses living in different geographical regions of Turkiye. The data of the study were obtained utilizing Nurses’ Disasters Prepardeness Perception Scale (NDPPS), Pyschological Resileince Scale (PRS) and Empathy Scale (ES).ResultsIn this study, the disaster preparedness perception of the nurses was found to be at medium level. More than half of the nurses (65.1%) reported that they did not received any disaster training before. A meaningful was found between the nurses’ disaster preparedness perceptions and their empathy levels and psychological resilence.ConclusionsAs in many countries, it is possible to state that also in Turkiye, the training of nurses for disasters are inadequate and that the studies on this subject are limited. This study will provide a theoretical platform to develop nurses' awareness of disaster preparedness and pyschological resilience and empathic approach programs to increase disaster resilience, and to conduct future research on disaster nursing.
Loss of function mutations at the tomato SSI2 locus impair plant growth and development by altering the fatty acid desaturation pathway
Authors: Quevedo‐Colmena A. S. , Ortiz‐Atienza A. , Jáquez‐Gutiérrez M. , Quinet M. , Atarés A. , Yuste‐Lisbona F. J. , Moreno V. , Angosto T. , Lozano R. 
Published: November 2023

Abstract

The stearoyl‐ACP desaturase (SACPD) is a key enzyme in the regulation of saturated to unsaturated fatty acid ratio, playing a crucial role in regulating membrane stability and fluidity, as well as photosynthesis efficiency, which makes it an important research focus in crop species.

This study reports the characterization and molecular cloning of pale dwarf (pad), a new tomato (Solanum lycopersicum L.) T‐DNA recessive mutant, which exhibits a dwarf and chlorotic phenotype. Functional studies of the T‐DNA tagged gene were conducted, including phylogenetic analysis, expression and metabolomic analyses, and generation of CRISPR/Cas9 knockout lines.

The cloning of T‐DNA flanking genomic sequences and a co‐segregation analysis found the pad phenotype was caused by a T‐DNA insertion disrupting the tomato homologue of the Arabidopsis SUPPRESSOR OF SALICYLIC ACID INSENSITIVITY 2 (SlSSI2), encoding a plastid localized isoform of SACPD. The phenotype of CRISPR/Cas9 SlSSI2 knockout lines confirmed that the morphological abnormalities in pad plants were due to SlSSI2 loss of function. Functional, metabolomic and expression analyses proved that SlSSI2 disruption causes deficiencies in 18:1 fatty acid desaturation and leads to diminished jasmonic acid (JA) content and increased salicylic acid (SA) levels.

Overall, these results proved that SSI2 plays a crucial role in the regulation of polyunsaturated fatty acid profiles in tomato, and revealed that SlSSI2 loss of function results in an inhibited JA‐responsive signalling pathway and a constitutively activated SA‐mediated defence signalling response. This study lays the foundation for further research on tomato SACPDs and their role in plant performance and fitness.
Revisiting scriptures: Unbinding a critical comparative subfield
Authors: Newton Ritchard 
Published: November 2023

Abstract“Scriptures” is a term provoking no shortage of anxiety for postmodern scholars. This literature review introduces theorists to a subfield committed to theorizing about that term in critical and comparative terms. Revisiting the contributions of classic and contemporary scholars, readers will learn how the analytical study of scriptures is being unbound from the baggage of the term's Christian provenance while also keeping its history, politics, and mediation in the fore.
Radiocarbon ages of microcrystalline authigenic carbonate in Lake Neusiedl (Austria) suggest millennial‐scale growth of Mg‐calcite and protodolomite
Authors: Neuhuber Stephanie , Gier Susanne , Draganits Erich , Steier Peter , Bolka Monika , Ottner Franz , Spötl Christoph , Hippler Dorothee , Meister Patrick 
Published: November 2023

ABSTRACTAuthigenic Mg‐calcite and dolomite are frequently observed in restricted, evaporative environments, such as lagoon or lake systems, but their formation is difficult to capture due to slow growth rates. Lake Neusiedl, an alkaline and subhaline lake with a mean water depth of 0.7 m in Austria, offers a natural system to study the precipitation of Ca‐Mg‐carbonate phases, which occur as fine‐grained, unconsolidated and largely homogenized mud. To elucidate the timing and formation mechanisms of these authigenic carbonate phases, the mineralogical and isotopic composition and radiocarbon age of different sediment grain‐size fractions from <0.2 to >3.0 μm were analysed. X‐ray diffraction analyses show two broad peaks of Mg‐calcite and protodolomite (lacking ordering peaks), suggesting that the carbonates are authigenic rather than detrital in origin. Calibrated carbon‐14 ages range between 200 cal yr bp and 3700 cal yr bp. The linear correlation of age and grain size suggests a very slow growth rate of single crystals of 0.23 to 0.60 μm/ka. These rates suggest an extremely slow sedimentation rate in a shallow lake that existed during most of the Holocene. The higher abundance of protodolomite in older grain fractions, in contrast to the presence of high‐Mg calcite in the youngest fractions, suggests a growth succession where high‐Mg calcite develops first and subsequently transforms into protodolomite. Much higher ages of 6 cal ka bp to 15 cal ka bp are measured in carbonates of lake deposits exposed on land, in a section north‐west of the recent lake, suggesting a growth rate of those carbonate minerals of 0.13 μm/ka. These time constraints further suggest that some carbonate grains could already have nucleated from lake water before or during the last glacial maximum, although under slightly different hydrochemical conditions.
Disclosure as family practice: Changing family dynamics in Hong Kong after a gay son comes out
Authors: Kong Travis S. K. 
Published: November 2023

AbstractThis paper examines the family dynamics between parents and gay sons after the latter's disclosure of their sexual orientation. Situated in the “doing family” and life course literature, the paper offers a sociological account of coming out and family dynamics in Hong Kong that presents the narratives of both gay sons and their parents, examining the changing moral and emotional economies of family life across two generations. Thirty‐five in‐depth individual interviews were conducted with a purposive sample of gay sons (n = 15) and their mothers (n = 14) and/or fathers (n = 6). The findings revealed that heteronormative family life, as part of the moral economy of family life, is challenged after disclosure, with parents forced to admit or accept the queer component of their family. Yet, both parents and gay sons work hard to accomplish a “correct” version of sexual normativity that views homosexuality as inborn (sexual essentialism) and conforms to the “good homosexual” image. Sons' disclosure also shifts the burden of the closet, as part of the emotional economy of family life, to their parents, especially mothers, on whom that burden often takes an emotional toll. The paper concludes that disclosure is a contested site of negotiation of the meaning of male identity, parenthood, and homosexuality, as well as a key family practice that changes the moral and emotional economies of families, eventually leading to the formation of new family forms. By viewing disclosure as family practice in a culture where intergenerational closeness and family co‐residence are prominent, this paper rethinks coming out, arguing that in the Chinese context it should be understood not only as identity politics, as it often is in Western contexts, but also as relational politics, thus revitalizing the coming‐out debate across cultural contexts and offering new insights on the relationship between homosexuality and contemporary family life.
All in, against all odds. Path shift in family policy via cross‐party agreement: the case of the Single Universal Allowance reform in Italy
Authors: Madama Ilaria , Mercuri Eugenia 
Published: November 2023

AbstractThe introduction of the Single Universal Child Allowance in 2021 marked a sharp turning point in Italian family policy. Presented as a major revolution aimed at combating the country's alarmingly low birth rates as well as child poverty, the reform was also meant to rationalise the benefits system while overcoming the historical fragmentation and uneven protection granted to families. Against this backdrop, the article contributes to the literature from two different angles. First, the study offers fresh empirical evidence of the path‐shifting scope of the reform, marking a rupture with the longstanding weak model of income support. Second, the article engages from an interpretative standpoint with the puzzling emergence of a cross‐party consensus around approval. Drawing from the comparative literature on institutional change and the modernisation of family policies, the article asks which factors made it possible—after decades of substantial inertia—to overcome path dependency through cross‐party agreement in Italy, providing an in‐depth, original examination of parties' positions throughout the legislative process and identifying key elements of agreement and conflict.
The CDX2 G allele and the FoKI F allele of the VDR gene are more prevalent and related to changes in vitamin D levels in patients with psoriasis vulgaris: A pilot study
Authors: AbdElneam Ahmed Ibrahim , Al‐Dhubaibi Mohammed Saleh , Bahaj Saleh Salem , Arshad Mohammad , Mohammed Ghada Farouk , Atef Lina Mohamed 
Published: November 2023

AbstractBackground and aimsPsoriasis is a chronic, non‐contagious autoimmune condition marked by dry, itchy,erythematous and scaly plaques. From modest, localized plaques to total body coverage, the severity of psoriasis varies. Plaque, guttate, inverted, pustular, and erythrodermic psoriasis are the five primary kinds. About 90% of cases are of plaque psoriasis, commonly known as psoriasis vulgaris. Study aims to determine the impact of an rs2228570 (FokI) variant and an rs11568820 (CDX2) variant on serum vitamin D levels (SVD) in patients with psoriasis, and the correlation between the two variants and disease severity.MethodsA case‐control study consisting of 95 psoriasis vulgaris patients and 84 healthy controls. The clinical investigation, molecular genetics analysis, and biochemical analysis were done for both groups.ResultsSVD levels were significantly decreased in psoriasis patients group. FokI genotypes analysis, we found no significant variance between groups. CDX2 G/G genotype is more prevalent in patients than controls. Moderate psoriasis vulgaris patients with CDX2 G/G genotypes have higher SVD levels than CDX2 G/A, and CDX2 A/A p = 0.003.ConclusionThe study found a difference in vitamin D levels between patients and healthy subjects, as well as a difference in vitamin D levels with different FoKI and CDX2 genotypes.
Faculty perspectives and values toward mathematics and science content information used in teacher preparation admissions processes
Authors: Slavit David , Roth McDuffie Amy , Griggs Nicole , Goldhaber Dan , Theobald Roddy 
Published: November 2023

AbstractThis qualitative study examines the information collected about applicants to mathematics or science teacher preparation programs (MSTPPs) and how university faculty perceive and value this information in admissions decisions. Based on document review and interviews with MSTPP faculty and admissions directors, we found that broad measures of mathematics and science content background (e.g., achievement test scores, past mathematics and science courses taken) were used more frequently than information on applicants‐specific mathematics and science content knowledge and dispositions. In many cases, application components (such as interviews and personal essay statements) were perceived by faculty to be conducive to surfacing applicants‐content knowledge and dispositions; however, they were not constructed or employed in a way that afforded the obtainment of this information. We highlight salient examples of MSTPPs‐collection and use of information related to mathematics and science and discuss implications for TPP admissions processes.
Effects of low‐density polyethylene and polyamide microplastics on the microbiological and chemical characteristics of an Andisol
Authors: Riveros Gustavo , Soria Rocío , Villafuerte Ana , Gómez Paloma , Ortega Raúl , Miralles Isabel , Schoebitz Mauricio 
Published: November 2023

AbstractMicroplastics (MPs) are a significant threat to soils. However, there is scarce information on the impact of MPs on soil properties, particularly in volcanic ash‐derived soils. The objective of this study was to evaluate the impact of polyamide (PA) and low‐density polyethylene (LDPE) MPs on the biological and chemical characteristics of an Andisol from central Chile. Twenty‐one parameters were evaluated, including pH, electrical conductivity (EC), total organic carbon (TOC), dissolved organic carbon (DOC), total phosphorus (TP), available phosphorous (AP), available nitrogen (AN), inorganic nitrogen forms (NH4+, NO2− and NO3), carbohydrates (CHO), polyphenols (POLs), humic substances, soil basal respiration (SBR) and activities of soil enzymes such as dehydrogenase, β‐glucosidase, phosphatase and urease. For this, a microcosm was set up in clay pots in an incubation chamber at 21°C and 60% soil moisture, with the addition of PA and LDPE at doses of 1% and 3% w/w; a control treatment consisting of microcosm without MPs was also included. After 6 weeks of incubation, PA addition resulted in an increase in TOC and NH4+ by up to 32% and 26%, respectively, and a decrease in NO3− by 22%. AP decreased by 15%–19% with the addition of PA and LDPE. Similarly, acid phosphatase and β‐glucosidase activities decreased by 15% and 26% with PA and LDPE, respectively. The distance‐based linear model (DistLM) was used to analyse relationships in chemical and biological datasets. The analysis revealed that TOC and TP were primary components in the best model for predicting microbiological changes (R2 = .469, AICs = 16.026), indicating that MPs accumulation affects soil carbon cycling and P content. Overall, the results show that MPs addition alters soil chemical and microbiological properties in Andisols, with varying effects depending on the type and dose of MPs, with the highest dose (3%) producing the most marked negative effects.
Long‐term fertilization regulates dissimilatory nitrate reduction processes by altering paddy soil organic carbon components
Authors: Li Chenglin , Wei Zhijun , Wang Xiaomin , Ma Xiaofang , Yang Pinpin , Shan Jun , Yan Xiaoyuan 
Published: November 2023

AbstractTo enhance rice yields, synthetic nitrogen (N) fertilizers are often applied in rice paddy fields. Under waterlogged conditions, denitrification, anaerobic ammonium oxidation (anammox) and dissimilatory nitrate reduction to ammonium (DNRA) are the main N transformation processes. However, the effects of long‐term fertilization on the dissimilatory nitrate reduction processes remain largely unclear. Here, we investigated rates of denitrification, anammox and DNRA and the abundance of bacterial and nitrate reduction‐related genes (16S rRNA, narG, nirK, nirS, nosZ and hzsB) in rice paddy fields under different fertilization regimes [i.e., non‐fertilization (CK), NPK fertilization (NPK) and NPK fertilization plus straw returning (NPKS)]. The rates of denitrification, anammox and DNRA in the CK treatment were 46.18, 0.35 and 1.29 nmoL N g−1 h−1, respectively, which were significantly (p < .05) increased by 7.32%–27.78%, 2.45–4.12 folds and 1.01–13.23 folds by NPK and NPKS treatments. This was largely consistent with the increased bacterial and nitrate reduction‐related gene abundances in the NPK and NPKS treatments. In addition, NPKS also significantly increased the relative contribution of DNRA to the total nitrate reduction relative to NPK and CK treatments, indicating that NPKS was more beneficial to N retention in the paddy field. Changes in rates of dissimilatory nitrate reduction processes in response to NPK and NPKS treatments were correlated to variations of soil total N, ammonium contents, pH, soil organic carbon (SOC) contents and nitrate reduction‐related genes, among which SOC contents had the highest explanation. Specifically, fulvic‐like compounds, alkyl C and methoxyl and nitrogen‐alkyl C were the key components determining denitrification, anammox and DNRA rates, respectively. Overall, our study suggests that long‐term NPK and NPKS fertilization stimulate rates of dissimilatory nitrate reduction processes mainly by altering soil C components and NPKS is more effective in maintaining soil fertility in the paddy field.
Patterns and outcomes of late onset thyroid disturbances after COVID‐19 vaccination: A report of 75 cases
Authors: Kaur Upinder , Reddy Noti Taruni Srija , Reddy Jaideep , Krishna Dondapati Venkata Vamshi , Dehade Amol , Agrawal Neeraj Kumar 
Published: November 2023

AbstractIsolated cases of subacute thyroiditis exist in the early period of COVID‐19 vaccination, largely after mRNA vaccines. Here we report late onset thyroid disturbances and persistent health issues in patients of thyroid disorders after COVID‐19 vaccination. Seventy‐five patients with post COVID‐19 vaccination thyroid disturbances were identified. Among these, 41 had flare of underlying thyroid illness, majority occurring at a median time lag of 28.4 weeks since 2nd dose. Thirty‐one cases of new onset hypothyroidism and three of new onset hyperthyroidism were reported, with a median time lag respectively of 17.2 and 22.6 weeks since 2nd dose. Most cases occurred after ChAdOx1‐nCoV‐19, which was the commonest vaccine employed in mass roll out in India. Significant improvement was observed in majority, after a median follow up of 22–26 weeks. New onset health issues persisting for ≥4 weeks were reported in 37.3% and were common in individuals with history of COVID‐19 before vaccine. New onset metabolic, musculoskeletal, and reproductive disorders were the common health complaints. Active monitoring is warranted for late onset adverse events after COVID‐19 vaccines of all types. Larger studies with involvement of unvaccinated individuals are required to understand the incidence and causality of late onset thyroid disturbances after COVID‐19 vaccines.
Origin and early divergence of tandem duplicated sorbitol transporter genes in Rosaceae: insights from evolutionary analysis of the SOT gene family in angiosperms
Authors: Yang Fan , Luo Jiawei , Guo Wenmeng , Zhang Yuxin , Liu Yunxiao , Yu Ze , Sun Yaqiang , Li Mingjun , Ma Fengwang , Zhao Tao 
Published: November 2023

SUMMARYSorbitol is a critical photosynthate and storage substance in the Rosaceae family. Sorbitol transporters (SOTs) play a vital role in facilitating sorbitol allocation from source to sink organs and sugar accumulation in sink organs. While prior research has addressed gene duplications within the SOT gene family in Rosaceae, the precise origin and evolutionary dynamics of these duplications remain unclear, largely due to the complicated interplay of whole genome duplications and tandem duplications. Here, we investigated the synteny relationships among all identified Polyol/Monosaccharide Transporter (PLT) genes in 61 angiosperm genomes and SOT genes in representative genomes within the Rosaceae family. By integrating phylogenetic analyses, we elucidated the lineage‐specific expansion and syntenic conservation of PLTs and SOTs across diverse plant lineages. We found that Rosaceae SOTs, as PLT family members, originated from a pair of tandemly duplicated PLT genes within Class III‐A. Furthermore, our investigation highlights the role of lineage‐specific and synergistic duplications in Amygdaloideae in contributing to the expansion of SOTs in Rosaceae plants. Collectively, our findings provide insights into the genomic origins, duplication events, and subsequent divergence of SOT gene family members. Such insights lay a crucial foundation for comprehensive functional characterizations in future studies.
Jasmonate activates secondary cell wall biosynthesis through MYC2‐MYB46 module
Authors: Im Jong Hee , Son Seungmin , Kim Won‐Chan , Kim Kihwan , Mitsuda Nobutaka , Ko Jae‐Heung , Han Kyung‐Hwan 
Published: November 2023

SUMMARYFormation of secondary cell wall (SCW) is tightly regulated spatiotemporally by various developmental and environmental signals. Successful fine‐tuning of the trade‐off between SCW biosynthesis and stress responses requires a better understanding of how plant growth is regulated under environmental stress conditions. However, the current understanding of the interplay between environmental signaling and SCW formation is limited. The lipid‐derived plant hormone jasmonate (JA) and its derivatives are important signaling components involved in various physiological processes including plant growth, development, and abiotic/biotic stress responses. Recent studies suggest that JA is involved in SCW formation but the signaling pathway has not been studied for how JA regulates SCW formation. We tested this hypothesis using the transcription factor MYB46, a master switch for SCW biosynthesis, and JA treatments. Both the transcript and protein levels of MYB46, a master switch for SCW formation, were significantly increased by JA treatment, resulting in the upregulation of SCW biosynthesis. We then show that this JA‐induced upregulation of MYB46 is mediated by MYC2, a central regulator of JA signaling, which binds to the promoter of MYB46. We conclude that this MYC2‐MYB46 module is a key component of the plant response to JA in SCW formation.