bluuebunny/crossref_metadata_2025_split huggingface dataset:
A good neighbor, a found treasure: Do local neighbors affect corporate innovation?
Authors: Cao Shaopeng , Cui Xin , Liao Jing , Wang Chunfeng , Yao Shouyu 
Published: January 2024

AbstractThis study examines whether local neighbors operating in different industries affect corporate innovation engagement. Based on mimetic isomorphism theory, we find that innovative local neighbors can serve as a social reference group for corporations to build legitimacy and guide corporations' mimetic innovation behavior. Our results remain robust after controlling for endogeneity by employing various methods. More importantly, our mechanism analysis indicates that local government activism is crucial to promote mimetic innovation behavior in a region. Our study provides a valid mechanism to explain the emergence of highly innovative cities that agglomerate across industry boundaries. Our research makes two key contributions to the literature. First, our study contributes to the literature on corporate innovation clustering by adding new evidence of the mimetic effects in corporate innovation across industries. Different from the industrial peer effects in innovation, which address the industrial peer effects through the lenses of competitiveness and information dissemination, our results highlight that mimetic isomorphism explains the regional effects of mimicry on corporate innovation. We find strong evidence indicating that firms imitate the innovation behaviors of their local neighbors, and this tendency is most plausibly explained by the incentives associated with acquiring legitimacy. Second, our findings clarify the mimetic behaviors in corporate innovation by extending the theory of mimetic isomorphism. We link local government activism to mimetic isomorphism from the psychological and sociological perspectives. In particular, our results indicate that local governments can implement activism through the psychological and sociological mechanisms illustrated in this study. Those “soft” mechanisms initiated by government contribute to a better understanding of the regional effects of mimicry on corporate innovation.
Treatment of onychomycosis in an era of antifungal resistance: Role for antifungal stewardship and topical antifungal agents
Authors: Gupta Aditya K. , Elewski Boni , Joseph Warren S. , Lipner Shari R. , Daniel C. Ralph , Tosti Antonella , Guenin Eric , Ghannoum Mahmoud 
Published: January 2024

AbstractA growing body of literature has marked the emergence and spread of antifungal resistance among species of Trichophyton, the most prevalent cause of toenail and fingernail onychomycosis in the United States and Europe. We review published data on rates of oral antifungal resistance among Trichophyton species; causes of antifungal resistance and methods to counteract it; and in vitro data on the role of topical antifungals in the treatment of onychomycosis. Antifungal resistance among species of Trichophyton against terbinafine and itraconazole—the two most common oral treatments for onychomycosis and other superficial fungal infections caused by dermatophytes—has been detected around the globe. Fungal adaptations, patient characteristics (e.g., immunocompromised status; drug–drug interactions), and empirical diagnostic and treatment patterns may contribute to reduced antifungal efficacy and the development of antifungal resistance. Antifungal stewardship efforts aim to ensure proper antifungal use to limit antifungal resistance and improve clinical outcomes. In the treatment of onychomycosis, critical aspects of antifungal stewardship include proper identification of the fungal infection prior to initiation of treatment and improvements in physician and patient education. Topical ciclopirox, efinaconazole and tavaborole, delivered either alone or in combination with oral antifungals, have demonstrated efficacy in vitro against susceptible and/or resistant isolates of Trichophyton species, with low potential for development of antifungal resistance. Additional real‐world long‐term data are needed to monitor global rates of antifungal resistance and assess the efficacy of oral and topical antifungals, alone or in combination, in counteracting antifungal resistance in the treatment of onychomycosis.
Understanding clinical outcomes and factors influencing mortality in intensive care unit patients with COVID‐19‐associated candidemia
Authors: Aydın Selda , Mert Ali , Yılmaz Mesut , Al Maslamani Muna , Rahimi Bilal Ahmad , Ayoade Folusakin , El‐Kholy Amani , Belitova Maya , Sengel Buket Erturk , Jalal Sabah , Albayrak Ayşe , Alatawi Jamayel Adnan , Szabo Balint Gergely , Ganeshan Ramesh Shankar , Nsutebu Emmanuel , Poojary Aruna , Akkoyunlu Yasemin , Alkan Sevil , Elik Dilşah Başkol , Eser‐Karlidag Gulden , Santos Lurdes , Moroti Ruxandra , Altın Nilgün , Gürbüz Esra , Ulusoy Tülay Ünver , Sipahi Oğuz Reşat , Çaşkurlu Hülya , Esmaoğlu Aliye , Lakatos Botond , El‐Sayed Nagwa Mostafa , Marıno Andrea , Cascio Antonio , Mihai Alexandru , Dumitru Irina Magdalena , Pshenichnaya Natalia , Ripon Rezaul Karim , Makek Mateja Jankovic , Rashid Naveed , Baljić Rusmir , Dascalu Cosmin , Sincan Gülden , Kızmaz Yeşim Uygun , Madendere Berk , Erdem Hakan 
Published: January 2024

AbstractBackgroundDuring the COVID pandemic, research has shown an increase in candidemia cases following severe COVID infection and the identification of risk factors associated with candidemia. However, there is a lack of studies that specifically explore clinical outcomes and mortality rates related to candidemia after COVID infection.ObjectivesThe aim of this international study was to evaluate the clinical outcomes and identify factors influencing mortality in patients who developed candidemia during their COVID infection.Patients/MethodsThis study included adult patients (18 years of age or older) admitted to the intensive care unit (ICU) and diagnosed with COVID‐associated candidemia (CAC). The research was conducted through ID‐IRI network and in collaboration with 34 medical centres across 18 countries retrospectively, spanning from the beginning of the COVID pandemic until December 2021.ResultsA total of 293 patients diagnosed with CAC were included. The median age of the patients was 67, and 63% of them were male. The most common Candida species detected was C. albicans. The crude 30‐day mortality rate was recorded at 62.4%. The logistic regression analysis identified several factors significantly impacting mortality, including age (odds ratio [OR] 1.04, 95% confidence interval [CI] 1.02–1.07, p < .0005), SOFA score (OR 1.307, 95% CI 1.17–1.45, p < .0005), invasive mechanical ventilation (OR 7.95, 95% CI 1.44–43.83, p < .017) and duration of mechanical ventilation (OR 0.98, 95% CI 0.96–0.99, p < .020).ConclusionsBy recognising these prognostic factors, medical professionals can customise their treatment approaches to offer more targeted care, leading to improved patient outcomes and higher survival rates for individuals with COVID‐associated candidemia.
Focal 18F‐fluorodeoxyglucose uptake in spinal dural arteriovenous fistula: A report of two cases
Authors: Hayashida Hitoshi , Masaki Katsuhisa , Ogata Hidenori , Yamaguchi Takahiro , Tanaka Koji , Arimura Koichi , Maruoka Yasuhiro , Kikuchi Kazufumi , Togao Osamu , Yamasaki Ryo , Isobe Noriko 
Published: January 2024

AbstractMagnetic resonance imaging of spinal dural arteriovenous fistula (SDAVF) shows longitudinally extensive spinal cord lesions mimicking neoplastic or inflammatory myelopathy. On positron emission tomography/computed tomography (PET/CT), we report two patients who showed focal 18F‐fluorodeoxyglucose (FDG) uptake in longitudinally extensive spinal cord lesions. These lesions were indistinguishable from tumors or myelitis but were finally diagnosed as SDAVF. Although PET/CT availability may be limited, in cases of myelopathy with diagnostic challenges, it is important to recognize that focal FDG uptake can be observed in SDAVF.
HLS1 promotes apical hook formation by regulating YUCCA8 and GH3.17 expression differently in the inner and outer side of the hook in cotton
Authors: Kong Xiangqiang , Zhou Jingyuan , Li Xue , Liu Cuimei , Chu Jinfang , Zhang Hui , Dong Hezhong 
Published: January 2024

AbstractHOOKLESS1 (HLS1) plays an indispensable role in apical hook development by promoting asymmetric auxin distribution in the hook. However, the precise mechanisms by which HLS1 regulates the differential gene expression in the inner and outer sides of the apical hook to promote this asymmetric auxin distribution remains unknown. The inner and outer sides of the cotton apical hook were separated for gene sequencing to search for differently expressed auxin‐related genes. Then, the GhYUCCA8 and GhGH3.17 genes, which are highly expressed in the inner and outer side, respectively, as well as GhHLS1, were silenced by the SSA‐VIGS method to study their interaction and function on auxin asymmetric distribution and hook formation. The hook formation was inhibited in the VIGS‐GhHLS1, VIGS‐GhYUCCA8 and VIGS‐GhGH3.17 seedlings. Silencing GhHLS1 decreased the expression of GhYUCCA8 on the inner side but increased the expression of GhGH3.17 on the outer side of the apical hook, which weakened the auxin asymmetric distribution in the hook. Our results indicated that the high expression of GhHLS1 in the inner side caused high expression of GhYUCCA8 and GhGh3.17 in the inner and outer side of the apical hook, respectively, which caused the gradient of free auxin between the inner and outer side and ultimately promoted apical hook formation.
Personalized tendon loading reduces muscle‐tendon imbalances in male adolescent elite athletes
Authors: Domroes Theresa , Weidlich Kolja , Bohm Sebastian , Mersmann Falk , Arampatzis Adamantios 
Published: January 2024

AbstractAn imbalanced adaptation of muscle strength and tendon stiffness in response to training may increase tendon strain (i.e., the mechanical demand on the tendon) and consequently tendon injury risk. This study investigated if personalized tendon loading inducing tendon strain within the effective range for adaptation (4.5%–6.5%) can reduce musculotendinous imbalances in male adolescent handball athletes (15–16 years). At four measurement time points during a competitive season, we assessed knee extensor muscle strength and patellar tendon mechanical properties using dynamometry and ultrasonography and estimated the tendon's structural integrity with a peak spatial frequency (PSF) analysis of proximal tendon ultrasound scans. A control group (n = 13) followed their usual training routine, an intervention group (n = 13) integrated tendon exercises into their training (3x/week for ~31 weeks) with a personalized intensity corresponding to an average of ~6.2% tendon strain. We found a significant time by group interaction (p < 0.005) for knee extensor muscle strength and normalized patellar tendon stiffness with significant increases over time only in the intervention group (p < 0.001). There were no group differences or time‐dependent changes in patellar tendon strain during maximum voluntary contractions or PSF. At the individual level, the intervention group demonstrated lower fluctuations of maximum patellar tendon strain during the season (p = 0.005) and a descriptively lower frequency of athletes with high‐level tendon strain (≥9%). The findings suggest that the personalized tendon loading program reduced muscle‐tendon imbalances in male adolescent athletes, which may provide new opportunities for tendon injury prevention.
Excluded workers and exempted employers: A qualitative study on domestic workers' access to social protection in the Netherlands
Authors: de Kort David , Bekker Sonja 
Published: January 2024

AbstractIn the Netherlands, many part‐time domestic workers fall within the scope of a particular type of labour law, that gives them fewer social protection rights and that renders private actors (households and workers) responsible for exercising those rights. Over the years, this policy has been criticised for institutionalising the differential treatment of domestic workers, which goes against ideas propagated in international initiatives, like the European Pillar of Social Rights. This contribution explores Dutch domestic workers' access to social protection in greater detail. Drawing on semi‐structured interviews with 30 domestic workers, we show that the actual access to social protection greatly varies over different workers and over different employment relationships of individual workers, but generally falls below par. Our findings indicate that this is partly due to the fact that the Dutch policy option underestimates domestic workers' wariness of placing demands on the households they work for, which raises questions over the desirability of non‐mediated employment relationships in the sector. We conclude with a brief discussion and suggestions for future policy directions.
Digital labour platforms and social dialogue at EU level: How new players redefine actors and their roles and what this means for collective bargaining
Authors: Piasna Agnieszka 
Published: January 2024

AbstractDigital labour platforms transform work and employment relations in many ways. Crucially, they renounce the role of the employer, leading to a redefinition of traditional categories of actors and their roles in social policy and dialogue. Using the example of the EU proposal for a directive on improving working conditions in platform work, this article examines how this redefinition is materialising in practice among social partners in order to understand its implications for the future of social dialogue and legislation. While previous research focused on the status of workers, this study takes a complementary view by considering the employer side as a key counterpart in a functioning employment relationship. The actor‐approach is used to analyse the views and positions of EU social partners and how their prerogatives are affected by the blurring of the role of the employer and the redefinition of traditional categories of actors in social policy.
A bibliometrics study on the status quo and hot topics of pathogenesis of psoriasis based on Web of Science
Authors: Yang Yujie , Zheng Xuwei , Lv Haiying , Tang Bin , Bi Yang , Luo Qianqian , Yao Danni , Chen Haiming , Lu Chuanjian 
Published: January 2024

AbstractBackgroundPsoriasis is an immune‐mediated chronic inflammatory skin disease. Great progress has been made in the pathogenesis of psoriasis in recent years, but there is no bibliometric study on the pathogenesis of psoriasis. The purpose of this study was to use bibliometrics method to analyze the research overview and hot spots of pathogenesis of psoriasis in recent 10 years, so as to further understand the development trend and frontier of this field.MethodsThe core literatures on the pathogenesis of psoriasis were searched in the Web of Science database, and analyzed by VOSviewer, CiteSpace, and Bibliometrix in terms of the annual publication volume, country, institution, author, journal, keywords, and so on.ResultsA total of 3570 literatures were included. China and the United States were the main research countries in this field, and Rockefeller University was the main research institution. Krueger JG, the author, had the highest number of publications and the greatest influence, and Boehncke (2015) was the most cited local literature. J INVEST DERMATOL takes the top spot in terms of the number of Dermatol articles and citation frequency. The main research hotspots in the pathogenesis of psoriasis are as follows: (1) The interaction between innate and adaptive immunity and the related inflammatory loop dominated by Th17 cells and IL‐23/IL‐17 axis are still the key mechanisms of psoriasis; (2) molecular genetic studies represented by Long Non‐Coding RNA (LncRNA); (3) integrated research of multi‐omics techniques represented by gut microbiota; and (4) Exploring the comorbidity mechanism of psoriasis represented by Metabolic Syndrome (MetS).ConclusionThis study is a summary of the current research status and hot trend of the pathogenesis of psoriasis, which will provide some reference for the scholars studying the pathogenesis of psoriasis.
An exploratory study of obstetrics trainees' experiences of breaking bad news
Authors: Julius V. , McCarthy G. 
Published: January 2024

AbstractIntroductionBreaking bad news is one of the hardest tasks performed by doctors. The news can significantly impact on the patient's life; however, the process also generates stress for the doctor. The aim of this study was to explore the lived experiences of breaking bad news for obstetrics trainees in Ireland.MethodsA qualitative study using interpretative phenomenological analysis (IPA) was performed to capture the experience of breaking bad news for the trainees. Semi‐structured interviews were conducted with trainees over Zoom. The transcripts were analysed in line with the IPA framework with the assistance of NVivo software.ResultsSeven trainees were interviewed, five at Basic Specialist Training (BST) level and two at Higher Specialist Training (HST) level. Four superordinate themes were identified from the analysis: “the reality of working in obstetrics,” “the role of the doctor,” “development of communication skills” and “the importance of the patient experience.” The trainees described breaking bad news in a variety of clinical contexts. This task could be emotionally draining; however, only two trainees mentioned ways of coping with this. Their formal training was limited with the majority of learning occurring “on the job.”ConclusionsThis study provides an insight into factors that influence trainees experiences of breaking bad news. The results complemented existing literature and raised questions about how to better support trainees through increased training and psychological support.
Visual Perception Principles in Constellation Creation
Authors: Kelly Bridget A. , Kemp Charles , Little Daniel R. , Hamacher Duane , Cropper Simon J. 
Published: January 2024

AbstractMany cultures share common constellations and common narratives about the stars in the night sky. Previous research has shown that this overlap in asterisms, minimal star groupings inside constellations, is clearly present across 27 distinct culture groups and can be explained in part by properties of individual stars (brightness) and properties of pairs of stars (proximity) (Kemp, Hamacher, Little, & Cropper, 2022). The same work, however, found no evidence that properties of triples (angle) and quadruples (good continuation) predicted constellation formation. We developed a behavioral experiment to explore how individuals form constellations under conditions that reduce cultural learning. We found that participants independently selected and connected similar stars, and that their responses were predicted by two properties of triples (angle and even spacing) in addition to the properties of brightness and proximity supported by previous work. Our findings lend further evidence to the theory that commonality of constellations across cultures is not a result of shared human history but rather stems from shared human nature.
THE EFFECTS OF DIFFERENT EGGSHELL-SILICONE BIOCOMPOSITE UNDER UNIAXIAL TENSILE LOADING
Authors: Azmi Nurul Nadiah , Gabrielle Marygrace Yong Poquita , Mohd Noor Nurul Muthmainnah , Hasnul Hisham Mohammad Hasmee Azmee 
Published: January 2024

Chicken eggshells are a major waste product in almost every country due to their extensive use as eggs are used in millions of household and industries. As a result, managing these waste products has become challenging as they not only occupy space in landfills but also release greenhouse gasses decomposition. In recent years efforts have been made to develop new materials using sustainable sources such as biocomposites. This study aims to fabricate eggshell silicone biocomposites and examine its behaviour under uniaxial tensile loading. This study consisted of two phases: fabrication of eggshell silicone biocomposite and mechanical testing under uniaxial tensile with 50 kN. During the first phase; eggshells were washed, sterilized, and crushed into powder form. Subsequently, they were mixed with silicone at different eggshell powder content (e.g., 5, 10 and 15 wt.%). In the second phase, the specimens underwent uniaxial tensile strength. The ultimate tensile strength increases from 0.43772 MPa to 0.47331 MPa from 5 wt.% to 10 wt.%. However, it decreases to 0.42535 MPa when reaches 15 wt.% eggshell weight. This study is in line with previous study that uses Arengga Pinnata silicone biocomposite.
Design and Analysis of Leaf Beam Single-Translation Constraint Compliant Modules and the Resulting Spherical Joints
Authors: Hao Guangbo , He Xiuyun , Zhu Jiaxiang , Li Haiyang 
Published: January 2024

Abstract
A wire beam is a single-translation constraint along its axial direction. It offers many applications in compliant mechanisms, such as being a transmitting/decoupling element connected to a linear actuator and being a fundamental constitutive element to design complex compliant joints and mechanisms. It is desired to find an alternative leaf beam single-translation constraint to equal a wire beam in order to improve the manufacturability and robustness to external loading. In this paper, we propose and model a new single-translation constraint compliant module, I-shape leaf beam design, to compare with a corresponding L-shape leaf beam design reported in the literature. Two spherical (S) joints using three I-shape leaf beams and three L-shape leaf beams, respectively, are then analytically modeled and analyzed. Three key geometric parameters are adopted to thoroughly assess four performance indices of each S joint, including stiffness ratio, rotation radius error, coupling motion, and parasitic motion. It shows that the I-shape leaf beam–based S joint performance indices are generally 10 times better than those of the L-shape leaf beam–based S joint. For each S joint, the optimal parameters are found under the given conditions. Finally, experimental tests are carried out for a fabricated S joint prototype using the I-shape leaf beams, the results from which verify the accuracy of the proposed analytical model and the fabrication feasibility.
Numerical Investigation of Classic Flutter Mechanism Under Circumferentially Non-Uniform Inlet Condition
Authors: Yan Zhaoqi , Pan Tianyu , Su Guanting , Li Qiushi , Kielb Robert E. 
Published: January 2024

Abstract
Over recent years, the aeroelastic problem of fan blades has become significantly serious due to the demand for high performance of aero-engines. To explore the aeroelastic issue of flutter, fan instability is represented by the aerodynamic damping. When the inlet condition is uniform, aerodynamic damping is mainly caused by the temporal factor, and the classic flutter usually does not occur due to the usage of mistuning. However, with the existence of circumferentially non-uniform components in the distorted inflow, aerodynamic damping is also affected by the spatial factor, which may alter the occurrence mechanism of classic flutter. To investigate this issue, the full-annulus 3D (three-dimensional) unsteady calculation is conducted on a transonic fan NASA Rotor 67 with a typical circumferential distortion inflow. As demonstrated by the energy method for the rotor blades at each nodal diameter, the coefficients of aerodynamic damping contain an interval value rather than a fixed datum. Some of the blades have positive damping, and others are negative. The positive and negative aerodynamic damping is determined by the relative position between the rotor blade and the distorted region in the circumferential direction. Furthermore, a fast calculation method based on the fundamental principle regarding flow periodicity is developed to obtain the aerodynamic damping at different nodal diameters under non-uniform inlet conditions.