bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analisis Faktor-Faktor Layanan Kesehatan dan Gizi Pada Penyelenggaraan PAUD Hi dalam Pencegahan Stunting
Authors: Yani Suryani  , Rivo Panji Yudha  
Published: January 2024

Penelitian ini bertujuan untuk mengetahui faktor-faktor layanan kesehatan dan gizi pada penyelenggaraan PAUD HI dalam mencegah stunting. Jenis penelitian ini adalah kuantitatif asosiatif. Polulasi penelitian ini terdiri dari kepala sekolah, guru serta wali murid yang berada di Lembaga PAUD Ranting Cikakak sebanyak 176 orang. Sample yang digunakan sebanyak 130 orang dengan tehnik pengambilan sampel menggunakan teknik purposive sampling. Tehnik pengumpulan data melalui kuesioner yang disebar melalui google form. Analisis data menggunakan analisa inner model dan outer model denggan bantuan Software smartPLS SEM (Partial Least Square – Structural Equation Modeling). Hasil penelitian ini menunjukkan bahwa 1) adanya hubungan langsung yang signifikan dari layanan kesehatan terhadap pencegahan stunting dengan melihat nilai original sampel sebesar 0,291, kemudian nilai T-Statistic sebesar 3,088 > 1,978 t Tabel dan nilai P-Value menunjukkan nilai 0,002 atau < 0,05, dengan nilai R Square 0,648 yang dipengaruhi salah satunya oleh layanan kesehatan dengan nilai F2 sebesar 0,405, 2) adanya hubungan langsung yang signifikan dari layanan gizi terhadap pencegahan stunting dengan melihat nilai original sampel sebesar 0.565, kemudian nilai T-Statistic sebesar 6.354 > 1,978 t Tabel dan nilai P-Value sebesar 0,000 atau < 0,05, dengan nilai R Square 0,648 yang dipengaruhi salah satunya oleh layanan gizi dengan nilai F2 sebesar 0.107.
Effect of alternate food sources on biological parameters of Stethorus pauperculus Weise (Coleoptera: Coccinellidae)
Authors: Godhani Hiteshkumar S. , Shukla Abhishek 
Published: January 2024

The effect of different alternate food sources on survival, mating frequency, fecundity and egg hatchability of Stethorus pauperculus was tested under laboratory conditions. None of the alternative hosts was able to maintain fertility of the female S. pauperculus, except the primary hosts which included two spotted red spider mite (Tetranychus urticae Koch), sorghum mite (Oligonychus indicus (Hirst)) and yellow mite (Polyphagotarsonemus latus (Banks)). Although some eggs were laid when S. pauperculus was supplied with pollen and honey mixture, they did not hatch. The most effective food source for maintaining adult longevity was T. urticae (39.30±1.08 days), followed by sorghum mite, O. indicus (29.75±0.67 days) and yellow mite (25.25±0.78 days).
PENGARUH PEMBERIAN TETES TERHADAP BIOGAS YANG DI PT ENERGI AGRO NUSANTARA
Authors: Fadhila Nur , Siswanti Nana Dyah 
Published: January 2024

Spent wash adalah limbah dari proses produksi alkohol. Tahap produksi alkohol mulai dari molase hingga terbentuk alkohol melalui fermentasi. Untuk setiap liter alkohol, maksimum 8 hingga 12 liter limbah cair dihasilkan. Limbah tersebut mengandung bahan organik dan mineral nutrient yang berasal dari tebu. Maka diperlukan proses pengolahan baik secara aerob maupun anaerob. Pengolahan limbah cair spent wash dapat diolah secara anaerob dengan dijadikan sebagai biogas. Pada unit Biogas Plant di PT ENERGI AGRO NUSANTARA mengolah limbah dari distilasi (spent wash) dan limbah dari sanitasi (spent lees) menjadi biogas dan pupuk hayati cair. Gas metana yang dihasilkan dari PT Energi Agro Nusantara sebesar 50-58% pada bulan Juni 2019 dan baku mutu yang telah ditetapkan PT Energi Agro Nusantara sebesar 60%. Pada proses anaerobic digestion dibutuhkan nutrisi untuk perkembangan mikroba salah satunya dengan penambahan tetes tebu. Tetes tebu (molasses) merupakan produk sisa pada proses pembuatan gula yang tidak dapat dikristalkan lagi. Tujuan percobaan ini adalah untuk mengetahui pengaruh penurunan COD , penambahan nutrisi berupa tetes tebu, volume yang dihasilkan biogas, dan pengolahan spent wash dengan metode anaerobic digestion.
"The Influence of Education using the Teams Games Tournament (TGT) Method to Enhance Knowledge of Pre-Disaster Preparedness for Mount Kelud Eruption in Students of Penataran 03 Elementary School."
Authors: Nurfinanda Pipit , Mujito Mujito 
Published: January 2024

Abstract: Preparedness is an activity to anticipate pre-disaster mitigation so that each individual is always ready and prepared to face natural disasters. This study aims to determine the knowledge of school-aged children about pre-disaster preparedness for the eruption of Mount Kelud. This study used a pre-experimental method with a sample size of 31 respondents taken through purposive sampling technique. Data collection was done using a questionnaire. The results of the study showed a significant increase in knowledge. The pre-test results showed that there were no respondents in the good knowledge category, but after being given education using the Time Games Tournament method, there were 23 respondents (74%) in that category. Additionally, the category of sufficient knowledge increased from 0% to 26%, and the category of poor knowledge decreased from 100% to 0%. The Time Games Tournament method is an effective learning technique for delivering pre-disaster preparedness knowledge in a fun way. This method can also increase students' spirit, enable them to actively participate, foster a sense of togetherness and mutual respect, and improve creativity. Therefore, educators and health workers are expected to apply an educational program using the Time Games Tournament learning method in conducting health education. Keywords: preparedness, education, Team Games Tournament method, school age child
The Effect of Benson Relaxation on Anxiety Levels In Major Surgical Preoperative Patients in the Dahlia Room Mardi Waluyo Blitar Hospital
Authors: Setiyono Agus , Sari Yeni Kartika , Pribadi Yohanes Kusuma 
Published: January 2024

Surgery can cause excessive fear and anxiety and can lead to complications. To reduce anxiety, non-pharmacological techniques is Benson Relaxation Therapi which is carried out by deep breathing and accompanied by beliefs held by the patient to achieve a relaxed state. Population on this research is preoperative major surgery patients. Sampling technique with Purposive Sampling 22 respondent. This research method : Quasy Experimental with One Group Pre-Test Post-Test, using questionnaire sheets, Standard Operating Procedures of Benson’s Relaxations, and Wilcoxon Sign Rank Test analysis. The purpose of study to determine the effect of Benson’s Relaxations on anxiety levels in preoperative major surgery patients. The Results of the Study : Using the analysis with the results of p-value = 0.000 which means <0.005. Conclusion : There is an effect of Benson’s Relaxation on the anxiety levels of pre operative major surgery patients. With the result of this reseach be used as a reference for Mardi Waluyo Blitar District Hospital in publishing of SPO Benson’s Relaxation it can be used to treat anxiety non-pharmacologically. Beside that, of nurses are expected to be able and willing to implement of Benson’s Relaxation which is proven effective in treating anxiety patients in all patients who experience anxiety in general.Keywords : Surgery, Benson Relaxation Technique, Anxiety
A doença periodontal como um fator agravante para a COVID-19
Authors: França Thaise Batista , Da Silva Karoline Rocha , Pereira Alan Oliveira , Pedroso Fabricio Hallef Fontes , Nascimento Yeska Gabriele Silva 
Published: January 2024

Recentemente, vários estudos sugeriram hipóteses para a potencial ligação inicial entre periodontite e complicações da COVID-19. Pode-se especular que um aumento nas bactérias periodontopatogênicas devido à má higiene oral agrava o quadro da COVID-19, já que as bactérias periodontopatogênicas podem influenciar na infecção por SARS-CoV-2 por aumentar a expressão de enzima conversora de angiotensina 2 (ACE2), que funcionam como um receptor para o coronavírus. Outra sugestão, que sustenta esse vínculo, são fatores de risco compartilhados, que incluem obesidade, idade, diabetes e hipertensão, entre outros. As superinfecções bacterianas são comuns em casos graves de COVID-19 e a tempestade de citocinas que ocorrem nesta doença tem muitos componentes comuns com o perfil de expressão de citocinas da doença periodontal, diante dessa semelhança observada na resposta inflamatória, podemos sugerir que há um relacionamento potencial entre COVID-19 e DP. O presente estudo foi composto mediante a compilação de 14 (quatorze) artigos publicados, em 2020 e 2021 e tem como principal objetivo realizar um levantamento bibliográfico através de uma revisão de literatura integrativa sobre uma possível relação entre doença periodontal e COVID-19, uma vez que o conhecimento sobre a conexão, se houver, entre a microbiota oral e complicações de COVID-19, são urgentes e necessários para estabelecer a importância da higiene oral e doenças bucais pré-existentes na gravidade e risco de mortalidade de COVID-19.
Cenário interprofissional de simulação de choque séptico em pediatria: qualificando o processo de ensino e aprendizagem
Authors: Silva Jaqueline Vitoria Bragato Pereira , Scota Luiz Antonio , E Silva Mariana Xavier 
Published: January 2024

O choque séptico é definido como uma resposta fisiológica contra um patógeno infeccioso, sendo importante causa de mortalidade na população pediátrica. Para aprimorar a formação de profissionais de saúde e capacitá-los no atendimento a pacientes com esse caso, foi criada e validada a simulação realística na graduação como principal pilar das metodologias ativas. A aplicação da simulação promove ao estudante o desenvolvimento de competências profissionais e interprofissionais, estimulando não somente as habilidades individuais, como também a atuação em conjunto com outras áreas médicas. Foi utilizada metodologia de pesquisa metodológica, fragmentada em 4 fases (elencar competências, construção cenário, seleção de juízes pelos Critérios de Ferring e validação do cenário), objetivando a elaboração e desenvolvimento de um instrumento científico que auxilie no ensino e aprendizagem do choque séptico pediátrico para estudantes de medicina e enfermagem. A partir da primeira rodada de validação do cenário por meio de análise descritiva dos itens, as considerações dos juízes, médicos e enfermeiros, foram revisadas e acatadas, sendo necessária a reformulação de determinados itens do cenário. Tais itens foram revistos na segunda rodada de validação, tendo 80% de concordância entre os juízes. Diante disso, este projeto pretendeu enfatizar a importância da educação interprofissional e da necessidade de inovar o ensino e criar novas metodologias de ensino e aprendizagem, objetivando melhores interações e funcionabilidade no trabalho interprofissional.
Aplicação do CRISPR-Cas9 no rastreio de linhagens de células tumorais como nova perspectiva na terapia de tumores
Authors: Oliveira Mi Hwa Morais , Peres Adrya Lúcia , Gomes Filho Sérgio Luiz da Rocha , Melo Willians Emanuel da Silva , Da Silva Bárbara Virgínia Mendonça , Brito Thaise Gabriele da Silva , De Andrade Fernanda Miguel , Simão Estefani Pontes 
Published: January 2024

Ao longo dos anos, os pesquisadores têm dedicado grandes esforços para entender e combater a adaptação do câncer, visando à cura. A arquitetura do câncer é complexa, composta por vários aspectos que tornam sua abordagem desafiadora. No entanto, essa complexidade também abre diferentes maneiras de abordar o problema. O campo da biologia tumoral tem uma vasta quantidade de literatura que é atualizada rapidamente. Portanto, descobrir o estado atual do conhecimento sobre a evolução do câncer e as ferramentas emergentes usadas nesses estudos pode proporcionar a clareza necessária para pesquisas futuras. Nesta revisão da literatura, foi apresentada uma visão geral das diferentes estratégias de aplicação da CRISPR-Cas9 na compreensão da evolução do tumor e seus respectivos níveis de contribuição. Foram selecionados artigos originais dos bancos de dados NCBI, Scielo e Biblioteca Virtual em Saúde que aplicaram a CRISPR-Cas9 para investigar a dinâmica tumoral. Através dos descritores "lineage tracing" "CRISPR-Cas9" "cancer" 22 artigos foram encontrados, e selecionados 12 artigos experimentais com base nos critérios estabelecidos. Por meio da análise desses artigos, foi averiguado que a incorporação da CRISPR-Cas nos estudos da evolução tumoral e na abordagem clínica do câncer proporcionou contribuições significativas. Seja por meio do desenvolvimento de modelos experimentais, da criação de marcadores moleculares ou do aprimoramento das técnicas de sequenciamento e rastreamento da linhagem tumoral. Apesar dos desafios inerentes à edição de genes, como a edição fora do alvo e mutações indesejadas, resultados promissores foram obtidos com a modificação da proteína Cas9 e do gRNA, tornando a ferramenta mais segura para uso em humanos.
Possibilidades de tratamento de pacientes submetidos a fratura na tíbia: revisão bibliográfica
Authors: Da Silva Neto Célio Gomes , Bueno Vinicius Ferreira Pires , De Araújo Fabrício Neiva 
Published: January 2024

Introdução: Um dos tipos mais frequentes de fratura óssea é a fratura tibial. Essa modalidade de lesão ocorre com maior prevalência em pessoas jovens e do sexo masculino. Em muitos casos, podem surgir complicações como: a necessidade de reoperação, infecção, pseudoartrose e consolidação viciosa. Objetivo: Este estudo tem como principal objetivo apresentar as atuais modalidades de tratamento para as fraturas da tíbia, evidenciando seus benefícios e limitações. Materiais E Métodos: foi analisado artigos do banco de dados da SciElo® e PubMed® que atenderam os seguintes critérios: data de inclusão 2016 a 2022; idiomas português e inglês; estar publicado na integra. Os achados científicos foram organizados dentro de quatro categorias, sendo elas: a redução incruenta seguida de imobilização gessada ou órtese; as fixações externas; as reduções cruentas com fixação extramedular e as fixações intramedulares. Resultados: a tomografia computadorizada auxilia na realização do diagnóstico e na programação cirúrgica. A artroscopia possibilita melhor visualização direta da superfície articular, sendo minimamente invasivo e pode ser uma opçao terapêutica no tratamento de fraturas articulares. O fixador externo circular tipo Ilizarov é um método simples e eficaz para o tratamento de fraturas da tibia com lesão extensa de partes moles associada. A haste intramedular é uma boa opção para o tratamento de fraturas diafisárias, possibilitando carga precoce e ganho progressivo de amplitude de movimento. A redução cruenta associado ao uso de órtese é mais utilizada em crianças. Conclusão: Observa-se que os métodos de tratamento, em geral, não demonstram ser superiores ou inferiores uns aos outros. Cada paciente e tipo de fratura deve ser avaliado de forma individualizada para a definição de um plano terapêutico.
Characteristics and Management of Pediatric Ocular Trauma
Authors: Wahyuni Laila , Sari Maya , Kartasasmita Arief S 
Published: January 2024

Background: To describe the characteristics of patients with ocular trauma in Cicendo Eye Hospital (CEH) Bandung, West Java.Methods: Data was taken from medical record of patients aged 0-14 between January to December 2011. The patient age, gender, visual acuity (before and after treatment), onset, types of trauma, laterality, location of trauma, causes and treatment were documented and analyzedResults: We found 188 children recorded with eye injury, 130 boys (69.1%) and 58 girls(30.9%) . Based on age distribution, eye trauma was mostly in group 2-7 years in 83 children (44.14%). The initial visual acuity obtained was mostly > 0.5 (Snellen chart) in 89 children (53,7%) and 0,02 â€“ LP of 11 children (50%) of closed globe injury and open globe injury respectively. Most patient came to CEH between 1-3 days of onset. Laterality of ocular trauma was mostly on the rigth eye (53,2%) and occur at out door (53,2%). The most causes of injury was blunt trauma 166 cases (88,3%). Medical management was needed in 141 cases, 46 cases had to been operated, and 1 cases just conservative.Conclusions: Ocular trauma was a common injury in preschool children, boys and right eye, mostly occur at out door, but those were no significant difference in both open and closed ocular trauma. Prognosis for visual function are mostly good in closed globe injury. We need more intensive supervision in the home especially outdoor enviroment, for that group of children.Â Key word: open globe injury, closed globe injury, Children, Cicendo eye hospital
Severity of Amblyopia and Its Correlation with The Amount of Refractive Error
Authors: Deneska Ria Sandy 
Published: January 2024

Background: To analyze the correlation between the severity of amblyopia and the amount of refractive errorMethods: Patients in outpatient clinic dr Soetomo General Hospital, who was diagnozed as amblyopia, from November 2011 â€“ January 2013, were enrolled in this retrospective study. All subjects were evaluated for subjective refraction using Snellen Chart and objective refraction using streak retinoscopy. The severity of amblyopia determined by the BCVA and the amount of refractive error stated by the spherical equivalent and the amount of cylindrical errors.Result: The subjects of this study was 40 patients (73 eyes) with age 5-11 years old. The range of BCVA was 0,1-0,8 logMAR units, the spherical equivalent of refractive errors were minus 1,5D â€“ 12,75D and the cylindrical errors were minus 0,50 â€“ 5,00D. Statistically, there was correlation between the severity of amblyopia and the spherical equivalent of refractive errors, but there was no correlation with the cylindrical errors.Conclusion: The severity of amblyopia has a correlation with the amount of spherical equivalent of refractive error, but has no correlation with the amount of astigmatism.Â Key words: Amblyopia, Spherical Equivalent, Cylindrical Error
Retinal Neurodegeneration on the Early Type 2 Diabetes Mellitus
Authors: Susilo Teguh , Rares Freddy , Poluan Herny 
Published: January 2024

Background: retinal neurodegeneration has been known to happen before any vascular lesion detected in the histological study in diabetic induced rats. This research was aimed to analyse neurodegeneration of the retina anatomically in vivo on the diabetic patient before any lesion could be seen clinically as the manifestation of microvascular disease.Method: comparative observational research was conducted on two groups, i.e. normal and NDR (no diabetic retinopathy) which fulfil the inclusion and exclusion criteria. The macular thickness of each group measured with Stratus OCT machine. The collected data was analysed statistically.Result: samples of 42 eyes collected from 21 patients in the normal group and 41 eyes collected from 22 patients in the NDR group. The normal group consisted of 20 (48%) males and 22 (55%) females while NDR group consisted of 17 (41%) males and 24 (59%) females. The age mean was 51.33 years on the normal group and 53.44 years on the NDR group. The sex and the age difference between the two groups had no statistical significance. Statistical analysis on the two groups showed very significant reduction of the macular thickness apply to all macula region except for the foveal minimal and superior outer which only showed significant reduction. The thinning of macula showed a greater extends of reduction on the fovea and inner ring compare to outer ring.Conclusion: there was thinning of macula as result of retinal neurodegeneration on the early diabetic patient before any microvascular lesion could be seen (no diabetic retinopathy/NDR).Â Keywords: neurodegeneration, diabetes mellitus, macular thickness, OCT
Comparison of Topical and Subconjunctival Curcumin Injection on Corneal Neovascularization on Alkali Injuries of Wistarâ€™s Cornea.
Authors: Y.A Rakhmasari , Inakawati Sri , Sundari Siti , Winarto Winarto , Sasmito Ediati 
Published: January 2024

Background: Neovascularization of the cornea causing loss of corneal clarity, decrease of visual acuity and also improve the failure of Keratoplasty. It can occur due to the imbalance of angiogenic and antiangiogenic factors such as on chemical trauma. Curcumin is the active extract which have anti-angiogenesis pharmacological effect. Subconjungtival injection have many advantages compared with topical administration. The purpose is to compare the effect of subconjunctival curcumin injection and topical curcumin on corneal neovascularization on alkali injuries of wistarâ€™s cornea.
Methods: Experimental study with post test only control group design using 28 male Wistar rat strain which received chemical trauma. The samples were randomly devided into 4 group. Topical curcumin 80 Î¼mol/L, topical DMSO 0,1% five times daily for 7 days. Subconjunctival injection of curcumin 40 Î¼mol/L and DMSO 0,1% were received once after the chemical trauma on the cornea. On day 8 was measured the corneal neovascularization in length of blood vessels and width of area. Statisticaly hypotheses with independent t-test and significant p < 0,05.
Result: Subconjunctival injection of curcumin group were significantly reduced the area of corneal neovascularization than topical curcumin group (p = 0,045).â€¨
Conclusion: Subconjunctival injection of curcumin needs further study to compare the benefits and side effect
The Challenges in Managing Proliferative Diabetic Retinopathy with Neovascular Glaucoma
Authors: Idham Putri A , Elvioza Elvioza , Victor Andi Arus , Andayani Gitalisa , Djatikusumo Ari , Ramayudatha Anggun 
Published: January 2024

Background: The aim of this study is to emphasize the importance of close monitoring of the disease progression, minimize late complication, and knowing the important parameters of succesful treatment.Methods: A 52 years old woman with proliferative diabetic retinopathy was referred to Vitreoretina division. Patient came with chief complaint blurry vision of the left eye. Patien was diagnosed with diabetes melitus type 2 since 10 months ago. At ophthalmological examination, there was iris neovascularization on the left eye. Due to this finding, patient was given treatment for the proliferative diabetic retinopathy and neovascular glaucoma.Results: The patient undewent intravitreal injection of bevacizumab and Kehki Meta implant surgery after panretinal photocoagulation laser. Neovascularization of the iris was regressed and the intraocular pressure was controlled.Conclusion: This patient underwent laser panretinal photocoagulation, bevacizumab injection and Keiki Mehta implant surgery. The result was good. The neovascularization was regressed. Closed monitoring should be continued to evaluate the progression of the disease and control the intraocular pressure to prevent further visual loss.Â Keywords: Proliferative diabetic retinopathy, neovascular glaucoma, diabetic macular edema