bluuebunny/crossref_metadata_2025_split huggingface dataset:
Representation of shared surface information and false memory for abstract versus concrete pictures in the conjoint recognition paradigm
Authors: Nieznański Marek , Ford Daria , Obidziński Michał 
Published: December 2023

AbstractAn effective factor by which false memories can arise is relatedness which includes not only semantic associations but also perceptual resemblance. This issue raises questions about how patterns of perceptual features are represented in memory and how they relate to semantic representations. In five experiments, we investigated the memory processes underlying the false recognition of perceptually or semantically related pictures from the perspective of fuzzy trace theory. Multinomial processing tree model analyses for the conjoint recognition paradigm showed that the parameter representing gist trace retrieval not only contributes to false acceptances of semantically related pictures, but also underlies the false recognition of non-semantically related abstract shapes. These results challenged the hypothesis that the false recognition of non-semantically related distractors is solely due to interference with the verbatim suppression process. These experiments also showed that adding a surface feature (colour) to the category exemplars increases false recognition of related distractors by enhancing the contribution of the familiarity process, but only for pictures of real objects. Comparisons between experiments showed that different variants of the conjoint recognition model, used to analyse the effects of the same experimental manipulation, can lead to partially different conclusions.
An emerging link between lncRNAs and cancer sex dimorphism
Authors: Naciri Ikrame , Andrade-Ludena Maria D. , Yang Ying , Kong Mei , Sun Sha 
Published: December 2023

AbstractThe prevalence and progression of cancer differ in males and females, and thus, sexual dimorphism in tumor development directly impacts clinical research and medicine. Long non-coding RNAs (lncRNAs) are increasingly recognized as important players in gene expression and various cellular processes, including cancer development and progression. In recent years, lncRNAs have been implicated in the differences observed in cancer incidence, progression, and treatment responses between men and women. Here, we present a brief overview of the current knowledge regarding the role of lncRNAs in cancer sex dimorphism, focusing on how they affect epigenetic processes in male and female mammalian cells. We discuss the potential mechanisms by which lncRNAs may contribute to sex differences in cancer, including transcriptional control of sex chromosomes, hormonal signaling pathways, and immune responses. We also propose strategies for studying lncRNA functions in cancer sex dimorphism. Furthermore, we emphasize the importance of considering sex as a biological variable in cancer research and the need to investigate the role lncRNAs play in mediating these sex differences. In summary, we highlight the emerging link between lncRNAs and cancer sex dimorphism and their potential as therapeutic targets.
Partial and Simultaneous Transitive Orientations via Modular Decompositions
Authors: Münch Miriam , Rutter Ignaz , Stumpf Peter 
Published: December 2023

AbstractA natural generalization of the recognition problem for a geometric graph class is the problem of extending a representation of a subgraph to a representation of the whole graph. A related problem is to find representations for multiple input graphs that coincide on subgraphs shared by the input graphs. A common restriction is the sunflower case where the shared graph is the same for each pair of input graphs. These problems translate to the setting of comparability graphs where the representations correspond to transitive orientations of their edges. We use modular decompositions to improve the runtime for the orientation extension problem and the sunflower orientation problem to linear time. We apply these results to improve the runtime for the partial representation problem and the sunflower case of the simultaneous representation problem for permutation graphs to linear time. We also give the first efficient algorithms for these problems on circular permutation graphs.
Stretched non-positive Weyl connections on solvable Lie groups
Authors: Bocheński Maciej , Jastrzȩbski Piotr , Tralle Aleksy 
Published: December 2023

AbstractWe determine the structure of solvable Lie groups endowed with invariant stretched non-positive Weyl connections and find classes of solvable Lie groups admitting and not admitting such connections. In dimension 4 we fully classify solvable Lie groups which admit invariant SNP Weyl connections.
Cognitive Behavioral Digital Interventions are Effective in Reducing Anxiety in Children and Adolescents: A Systematic Review and Meta-analysis
Authors: Csirmaz Luca , Nagy Tamás , Vikor Fanni , Kasos Krisztian 
Published: December 2023

AbstractAnxiety disorders are the most prevalent mental health issues in childhood, yet most children do not receive treatment. With recent advances in technology, a growing number of digital anxiety interventions are becoming accessible. This study is the first meta-analysis to evaluate the effectiveness and usefulness of digital cognitive-behavioral anxiety interventions for individuals under the age of 18. Five electronic databases (PsycNET, Web of Science, Science Direct, Pub Med, SAGE Journals.) were systematically searched in 2021. Inclusion criteria were: randomized control trials with a wait list no treatment control, standalone to blended care with minimal therapist involvement, diagnosed anxiety disorder or elevated levels of anxiety, outcome anxiety levels had to be assessed by a clinician, or the patients themselves by a validated anxiety measure. We assessed and controlled for publication bias, and considered the risk of bias using the Cochrane risk-of-bias tool. Eighteen studies were found eligible, which examined 1290 participants in total. Pooled effect sizes using a random-effects model yielded low overall effect for self-ratings (g = 0.28, k = 18, p < 0.001, 95% CI [0.14; 0.41]), and medium effect for ratings of clinicians (g = 0.66, k = 13, p < 0.001, 95% CI [0.50; 0.80]) as well as for parental report (g = 0.49, k = 16, p < 0.001, 95% CI [0.29; 0.69]). We found that the effects were homogenous across studies. Further examining potential moderating factors of treatment efficacy is needed in future research, as well as conducting studies that compare traditional methods of care to their digital counterparts. Digital interventions could contribute to the well-being of children regardless of age, minimizing therapist involvement. We conclude that digital cognitive-behavioral interventions may provide an accessible, cost-effective, and scalable anxiety treatment option for children and adolescents.
Influence of data selection on aquatic ecotoxicity characterization factors for selected persistent and mobile substances
Authors: Aggarwal Rahul , Holmquist Hanna , Arvidsson Rickard , Reppas-Chrysovitsinos Efstathios , Peters Gregory 
Published: December 2023

Abstract
Purpose
This paper addresses the lack of ecotoxicity characterization factors (CFs) for persistent and mobile (PM) chemicals in life cycle assessment. The specific aims are (1) to provide CFs for 64 selected chemicals and benchmark them against the USEtox database, (2) to propose an ecotoxicity data harmonization strategy, and (3) to analyze the influence of ecotoxicity data sources and data harmonization strategies.

Methods
Sixty-four per- and polyfluoroalkyl substances (PFAS), triazines, and triazoles were selected. An ecotoxicity data harmonization strategy was developed to ensure data consistency. A screening strategy for including transformation products was also developed. Existing CFs in the USEtox organic substances database (version 2.01) were identified, and new CFs were calculated based on available data sources. The USEtox model (version 2.13) was used for calculations, and the collected ecotoxicity data from different sources were varied to test their influence.

Results and discussion
The ecotoxicity data harmonization strategy excluded a considerable amount of incompatible data. To the list of 64 chemicals, 3 transformation products were added. Out of the 67 chemicals, experimental ecotoxicity data were available for 47, leading to the use of in silico tools and average values to fill data gaps for 20 chemicals. CFs for 67 chemicals could thus be provided. Comparing CFs calculated based on experimental and estimated ecotoxicity data reveals that the estimated data leads to considerably different CF values.

Conclusions
The paper provides strategies for ecotoxicity data harmonization and the inclusion of transformation products. The limited availability of experimental ecotoxicity data and differing results of the applied estimation methods highlight the need for further development of estimation methods. In addition, further development in including transformation products is recommended, which is particularly relevant for PM chemicals.
Photostimulation of lymphatic clearance of β-amyloid from mouse brain: a new strategy for the therapy of Alzheimer’s disease
Authors: Li Dongyu , Lin Hao , Sun Silin , Liu Shaojun , Liu Zhang , He Yuening , Zhu Jingtan , Xu Jianyi , Semyachkina-Glushkovskaya Oxana , Yu Tingting , Zhu Dan 
Published: December 2023

AbstractAlzheimer’s disease (AD) is an age-related neurodegenerative disorder that poses a significant burden on socio-economic and healthcare systems worldwide. However, the currently available therapy of AD is limited, and new strategies are needed to enhance the clearance of β-amyloid (Aβ) protein and improve cognitive function. Photobiomodulation (PBM) is a non-invasive and effective therapeutic method that has shown promise in treating various brain diseases. Here, we demonstrate that 1267-nm PBM significantly alleviates cognitive decline in the 5xFAD mouse model of AD and is safe as it does not induce a significant increase in cortical temperature. Moreover, with the combination of 3D tissue optical clearing imaging and automatic brain region segmentation, we show that PBM-mediated reductions of Aβ plaques in different subregions of prefrontal cortex and the hippocampus are different. The PBM-induced lymphatic clearance of Aβ from the brain is associated with improvement of memory and cognitive functions in 5xFAD mice. Our results suggest that the modulation of meningeal lymphatic vessels (MLVs) should play an important role in promoting Aβ clearance. Collectively, this pilot study demonstrates that PBM can safely accelerate lymphatic clearance of Aβ from the brain of 5xFAD mice, promoting improvement of neurocognitive status of AD animals suggesting that PBM can be an effective and bedside therapy for AD.
Graphical Abstract
Modes of Bonding and Morphogenesis. Deleuze, Ruyer, and the Rearticulation of Life and Nonlife
Authors: Pugliaro Francesco 
Published: December 2023

AbstractThis paper takes up some threads of Deleuze’s and Ruyer’s engagement with biology. I begin by laying out the main features of Deleuze’s scheme of morphogenesis, through the lens of his references to embryology. I take Deleuze’s interest in embryology to be guided by the effort to define bodies solely by form-generating factors which are immanent to them. His concept of virtuality, which indicates the creative component of reality, the open field of connections defining a body’s capacities for transformation and interaction, plays a key role in this regard. I then consider two implications: (1) The insistence on morphogenesis displaces the question of life from given biological entities, which preserve themselves and act through regulated cycles, to the myriad of activities that compose and modify them; (2) It also rearticulates the distinction between the living and the nonliving, in that it separates the question of life from that of its emergence from a given material arrangement. In the second part I examine these points with greater reference to Ruyer. After introducing Ruyer’s concepts of functioning and formation, I focus on his account of the continuity between biological and physicochemical forms, following some of his work on the microbiology and ethology of the time. The real difference is not between the living and the nonliving, but between two modes of bonding and composition variously operating on all scales: morphogenetic and statistical. I conclude by assessing the significance of this claim with respect to the traditional distinction between vitalism and mechanism.
Absolute dating of construction materials and petrological characterisation of mortars from the Santalla de Bóveda Monument (Lugo, Spain)
Authors: Blanco-Rotea Rebeca , Sanjurjo-Sánchez Jorge , Freire-Lista David M. , Benavides-García Rosa 
Published: December 2023

AbstractThe construction materials of the Santalla de Bóveda Monument, one of the most studied buildings in Galicia (Spain), are analysed to date the mortars and bricks of walls and vaults by combining three dating techniques: optically stimulated luminescence, radiocarbon and thermoluminescence. Petrological characterisation of the mortars themselves is carried out. Until now, the paintings on the vault have been interpreted as Roman, early Christian or Pre-Romanesque, depending on the interpretative framework used by the researcher who studied them. There is also no consensus on their functionality. A total of 21 samples were collected, and 39 datings were made. The results are conclusive: the original building dates from the second half of the fourth century AD, the paintings date from the beginning of the seventh century or the upper floor from the tenth to twelfth centuries. These results make it necessary to review the history of Galician architecture between Late Antiquity and the Early Medieval Ages.
Advancing spacecraft demisability through a novel composite bolt joint system: a step toward sustainable and safe space environments
Authors: Looten Alexandre A. , Vodermayer Albert , Caiazzo Antonio , Usinger Ralf , Richard Muriel , Michaud Véronique 
Published: December 2023

AbstractFrom the recent awareness of the booming number of space debris and their derived worldwide re-entry event threat originating from the use of high survivability components, complementary mitigation measures must be taken for future orbital elements. In this direction, the implementation of a design for demise at an early stage of spacecraft conception allows a progressive and effective solution. As part of a collaborative effort launched by École Polytechnique Fédérale de Lausanne and the European Space Agency, we focus on the evaluation of polymer composite bolts as the main structural satellite panel fastening systems to improve the overall spacecraft demisability during its destructive re-entry into the atmosphere as compared to baseline critical systems, while maintaining equivalent mission-relevant properties. Two carbon fiber-reinforced polyetheretherketone (PEEK) designs were compared to a stainless steel baseline in terms of static properties at room temperature, dynamic properties over a temperature range, as well as demise capability by static re-entry simulation testing. The results led us to identify a promising short CF/PEEK composite bolt design.
Noncytotoxic Carbon Nanotubes Bioconjugated with Fucosyltransferase 4-Derived Peptides Modulate Macrophage Polarization In Vitro
Authors: Guzmán-Mendoza J. J. , Sánchez-Ramírez B. , Cigarroa-Mayorga O. E. , Orrantia-Borunda E. , Talamás-Rohana P. 
Published: December 2023

AbstractImportant developments in nanoparticle-based therapies have occurred in recent years. Carbon nanotubes (CNTs) are among the most valuable nanoparticles because of their physicochemical properties and functionalization possibilities; therefore, they are proposed as peptide carriers for immunotherapy. Immunotherapy has been explored as a promising treatment for ovarian cancer (OvCa), and it has been reported that macrophage polarization to M1 and M2 phenotypes plays a pivotal role in OvCa initiation, progression, and metastasis, providing therapeutic targets for macrophage-targeted treatment. In this work, we explored the initial stages of designing CNT-based immunotherapy for OvCa using fucosyltransferase-4-derived T-cell epitopes conjugated with CNTs (f-CNTs). Their cytotoxicity and biological interactions were analyzed in macrophages (J774A.1) and human ovarian cancer cells (SKOV-3). Here,f-CNTs did not show cytotoxicity at concentrations < 6 μg/mL; additionally, they induced morphological changes and activation in macrophages; time-dependent uptake in lysosomes; production of M1-like cytokines; upregulation of CD80, CD86, and major histocompatibility complex II (MHC II); and downregulation of arginase-1 (ARG-1). In conclusion,f-CNTs exhibited biocompatibility in both cell lines and displayed M1-like polarization in macrophages, and we propose their exploration as a peptide carrier system for macrophage activation and polarization in ovarian cancer immunotherapy.
The effect of a combined rehabilitation program on the temporomandibular joint in systemic sclerosis evaluated by ultrasound exam
Authors: Melchiorre Daniela , Passalacqua M. , Maresca M. , Landi G. , Bagni M. A. , El Aoufy K. , Baccini M. , Matucci-Cerinic M. , Maddali Bongi S. 
Published: December 2023

Abstract
Purpose
Temporomandibular joint (TMJ) involvement is frequent in Systemic Sclerosis (SSc). Dysfunction and X-ray changes of TMJ were described only in few observational studies. Treatment as well has been seldom considered. Aim of the present study was to evaluate the effects on TMJ of two specifically designed physiotherapy protocols.

Methods
The study group included 26 SSc outpatients (22 females and 4 males with mean age ± SD 59.08 ± 10.31 years). Thirteen patients were randomly assigned to a treatment (protocol 1) including home exercises for TMJ and thirteen to a treatment (protocol 2) including home exercises and a combined procedure. The rehabilitation effects on the TMJ were evaluated by ultrasound examination (UE) in static and dynamic phases. UE was performed in all patients before and at the end of the treatment and after a follow up (8 weeks).

Results
Both rehabilitation protocols induced a significant improvement (protocol 1: p < 0.01 and protocol 2: p < 0.005) of mouth opening with a long-lasting effect. Protocol 2 was more effective than protocol 1. A significant increase of bilateral condyle-head temporal bone distance was detected by UE at the end of both treatments. It was maintained at follow-up in patients treated with Protocol 2.

Conclusions
The present investigation shows that a rehabilitation program characterized by home exercises with a combined procedure is useful to recover the function of TMJ. The data also show that UE is helpful in the evaluation of TMJ in SSc and in the assessment of the efficacy of the rehabilitation programs.
Designing for dissemination among public health and clinical practitioners in the USA
Authors: Shato Thembekile , Kepper Maura M. , McLoughlin Gabriella M. , Tabak Rachel G. , Glasgow Russell E. , Brownson Ross C. 
Published: December 2023

AbstractIntroduction:The slow adoption of evidence-based interventions reflects gaps in effective dissemination of research evidence. Existing studies examining designing for dissemination (D4D), a process that ensures interventions and implementation strategies consider adopters’ contexts, have focused primarily on researchers, with limited perspectives of practitioners. To address these gaps, this study examined D4D practice among public health and clinical practitioners in the USA.Methods:We conducted a cross-sectional study among public health and primary care practitioners in April to June 2022 (analyzed in July 2022 to December 2022). Both groups were recruited through national-level rosters. The survey was informed by previous D4D studies and pretested using cognitive interviewing.Results:Among 577 respondents, 45% were public health and 55% primary care practitioners, with an overall survey response rate of 5.5%. The most commonly ranked sources of research evidence were email announcements for public health practitioners (43.7%) and reading academic journals for clinical practitioners (37.9%). Practitioners used research findings to promote health equity (67%) and evaluate programs/services (66%). A higher proportion of clinical compared to public health practitioners strongly agreed/agreed that within their work setting they had adequate financial resources (36% vs. 23%,p< 0.001) and adequate staffing (36% vs. 24%,p= 0.001) to implement research findings. Only 20% of all practitioners reported having a designated individual or team responsible for finding and disseminating research evidence.Conclusions:Addressing both individual and modifiable barriers, including organizational capacity to access and use research evidence, may better align the efforts of researchers with priorities and resources of practitioners.
A social science mixed-methods approach to stimulating and measuring creativity in the design classroom
Authors: Raghunath Nilanjan , Koronis Georgios , Karthikayen Rianne , Silva Arlindo , Yogiaman Christine 
Published: December 2023

Abstract
This study aimed to evaluate the effectiveness of using a social science mixed-methods approach to stimulate creativity and improve the attainment of creative outcomes in teaching design. In a focused study framed through a design collaborative experiment within a classroom context, sketches produced by a sample of 351 students were analyzed and the impact of stimuli was categorized by visual, physical, quantitative and contextual information on creative processes and outcomes in product design. Sixteen combinations of these stimuli were integrated as parameters of design briefs (DBs) given to the participating students. This research was augmented with a survey to understand participants’ perceptions and reactions and was rated by expert judges. The results demonstrate that certain combinations of quantitative and qualitative stimuli have a positive impact on creative processes and outcomes. These findings will inform new techniques for engaging and inspiring students in design studies.
Bracket words along Hardy field sequences
Authors: KONIECZNY JAKUB , MÜLLNER CLEMENS 
Published: December 2023

AbstractWe study bracket words, which are a far-reaching generalization of Sturmian words, along Hardy field sequences, which are a far-reaching generalization of Piatetski-Shapiro sequences
$\lfloor n^c \rfloor $
. We show that sequences thus obtained are deterministic (that is, they have subexponential subword complexity) and satisfy Sarnak’s conjecture.