bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adenocarcinoma of sigmoid colon with metastasis to an ovarian mature teratoma: A case report
Authors: Wang Wei , Lin Chun-Chi , Liang Wen-Yi , Chang Shih-Ching , Jiang Jeng-Kai 
Published: January 2024

BACKGROUND
Colorectal cancer ranks third in global cancer-related mortality, often due to metastases to liver and lungs. Ovarian metastases are less common, accounting for 3.6% to 7.4% of cases. In contrast, mature ovarian teratomas are frequently benign. Tumor-to-tumor metastasis is a rare phenomenon, with a limited number of documented cases. Three cases of mature ovarian teratomas metastasizing from different cancers have been reported. This report focuses on a case of tumor-to-tumor metastasis from sigmoid colon adenocarcinoma to a mature ovarian teratoma.
CASE SUMMARY
A 41-year-old Taiwanese woman with no known systemic diseases presented with lower back pain, which led to imaging revealing malignant lesions in the spine, pelvis, liver, and multiple lung metastases. She was diagnosed with sigmoid colon adenocarcinoma with metastases to the liver, lung, bone, and a left ovarian teratoma. Treatment involved radiotherapy and chemotherapy, resulting in regression of the primary tumor and stable lung and liver lesions. Due to abdominal symptoms, she underwent exploratory surgery, unveiling a mature teratoma in the left ovary with signs of metastatic adenocarcinoma.
CONCLUSION
Consider resecting mature ovarian teratomas with concurrent colorectal adenocarcinoma to prevent tumor-to-tumor metastasis.
DESCRIPTION OF A COLLECTION OF SALVIA SCLAREA L. IN TERMS OF ITS BIOCHEMICAL PROPERTIES
Authors: Nevkrytaya Natal'ya Vladimirovna , Krivchik Nina Sergeyevna , Krivda Svetlana Ivanovna , Skipor Oleg Boleslavovich , Grunina Yelena Nikolayevna 
Published: January 2024

The study object is the accumulation of essential oil in the inflorescences of clarysage, the content of its main components and the sclareol yield. The study purpose is to analyze a collection of clarysage (112 specimens) in terms of the basic biochemical properties (the essential oil content in raw material, its chemical composition and the sclareol yield) and to identify the specimens showing good prospects for inclusion in the breeding process. The study was carried out in 2018–2020 at the experimental plot of the Research Institute of Agriculture of Crimea located in the piedmont region of Crimea (KrymskayaRoza village, Belogorsk district). The climate is moderate continental. The average year-round temperature is +10 °С. The average year-round air humidity is 70%, the hydrothermic factor is 0.91. The accounting and analyses were performed in accordance with the techniques developed. The study revealed higher degree of genetic determination of the essential oil buildup in plants as compared to the weather effect. As noted, increased precipitation and extremely high temperatures during the plant flowering and seed formation time affect negatively the sclareol buildup. The variability of the properties analyzed (Cv=7.8–23.4%) bears evidence to a feasibility of selecting promising parent material for breeding. Based on the outcomes of the collection analysis there have been isolated 12 specimens leaving behind the varieties cultivated in terms of the basic biochemical properties including five specimens with a high mass fraction of essential oil – 0.90–1.06% on the dry basis (as compared to 0.6–0.88% in the varieties cultivated) and seven specimens with a high sclareol content in raw material – 2.00–2.35% (as compared to 1.58–1.71% in the varieties cultivated).
Agentive Cognitive Construction Grammar: a predictive semiotic theory of mind and language
Authors: Torres-Martínez Sergio 
Published: January 2024

Abstract
This paper introduces a novel perspective on Agentive Cognitive Construction Grammar (AgCCxG) by examining the intricate interplay between mind and language through the lens of both Active Inference and Peircean semiotics. AgCCxG emphasizes the impact of intention and purpose on linguistic choices as a cognitive imperative to balance the symbolic Self (Intelligent Agent) with the dynamics of the environment. Among other things, the paper posits that linguistic constructions, particularly Constructional Attachment Patterns (CAPs), like argument structure constructions, embody experienced interactions with the world through reenactment routines via the integration of multisensory channels. Unlike traditional usage-based approaches (e.g., construction grammars), AgCCxG embraces a robust theory of signs that reveals human representation as a continuous process of semiotic hybridization for the creative prediction of uncertain scenarios. Importantly, the paper challenges the notion of the mind as a unified, rational, uncertainty-reducing machine by asserting that physical processes governing open biological systems profoundly influence the linguistic sign system. Intelligent agents’ adaptability in expressing incongruous realities thus highlights the role of semiotic hybridization in preserving an agent’s autonomy and semiotic boundary.
Bienestar Psicológico y Espiritualidad
Authors: Acosta Díaz Emilio 
Published: January 2024

140Tiempos Nuevos. Año 28. No. 30. (2023). pp. 140 - 152 https://doi.org/10.15658/rev.inst.tiempnuevos23.12283014Bienestar Psicológico y Espiritualidad:Factor Protector de la Salud Mental y Calidad de VidaPsychological Well-Being and Spirituality:Protective Factor for Mental Health and Quality of LifeEmilio Acosta Díaz1ResumenEn las actuales circunstancias en las que se da el desarrollo de la persona, son diversos y variados los desafíos en torno al bienestar psicológico y espiritual; el presente artículo trata de reconocer el bienestar a partir de dos criterios: salud mental y calidad de vida. El esfuerzo por ubicar un horizonte de comprensión de la realidad desde cuatro ámbitos importantes como son: el escenario de interacción, la esencia del ser humano, su capacidad inteligente y el sentido de trascendencia, se convierten en rutas claves para entender mejor la salud mental y la calidad con la que se debe aprender a administrar la vida.
Este ejercicio de reflexión y comprensión hermenéutica, tanto de la realidad como del movimiento de la vida, permitirá tener una visión integral en orden al cuidado de la salud mental y la calidad de vida en todas las fases evolutivas de la misma, toda vez que el bienestar psicológico y espiritual se encarga de mantener el equilibrio emocional y motiva a vivir de manera organizada y con calidad la vida.
La construcción del paisaje queer en torno al Mediterráneo
Authors: BAROS TOWNSEND MAURICIO 
Published: January 2024

Esta investigación tiene por objetivo abordar dos conceptos, cuales son la liminalidad y lo queer a partir del análisis de los viajes y estadías en torno del Mediterráneo realizados por prominentes artistas durante los siglos XIX y XX. El supuesto hipotético plantea que el Mediterráneo ha ofrecido las condiciones liminales que le ha permitido convertirse en el destino preferido de viajeros con una orientación sexual queer. Estos personajes han plasmado sus intereses sexuales tanto en su obra literaria, pictórica, fotográfica, cinematográfica, etc., creando de esta manera una geografía íntima y personal que terminó por plasmarse en una arquitectura, que sirvió como refugio y teatro para su doble existencia homosexual. En ellas es posible apreciar toda una estética que podemos denominar como queer, que parte en la arquitectura y termina en la vestimenta, y que ha sido posible construir gracias a la existencia de este Mediterráneo liminal.
PALABRAS CLAVE: Queer, liminalismo, Mediterráneo, Orientalismo, arquitectura.
Język bohaterów w utworach Michaiła Zoszczenki
Authors: Wierzbiński Jarosław 
Published: January 2024

Twórczość Michaiła Zoszczenki przenosi nas w lata socrealistycznej ortodoksji, kiedy względy ideologiczne odgrywały pierwszoplanową rolę w rozmaitych sferach życia. W języku jego bohaterów manifestują się takie zjawiska, jak upolitycznienie słownictwa, manipulacje semantyczne, przewrotna argumentacja, spiętrzenie absurdów, a także fikcyjna konwersacja graniczącą nierzadko z pustosłowiem.
Wśród przykładów spekulowania słownictwem znajduje się termin идеология, który nie powinien mieć zastosowania w rozmaitych konsytuacjach. Adresatom tego słowa imputuje się cechy o wydźwięku politycznym. Intencją jego użytkowników jest wykreowanie przeciwnika politycznego. Zdumiewa też łatwość, z jaką bohaterowie Zoszczenki poddają się manipulacjom językowym, nie popadając przy tym w najmniejsze zakłopotanie. Wręcz przeciwnie, akceptują swoje nielogiczne wywody, aprobują też niezrozumiałe wypowiedzi przedstawicieli władzy.
Zasygnalizowane w artykule zjawiska są symptomatyczne i znamienne dla języka, odzwierciedlającego czasy Zoszczenki. Zoszczenko ujawnił w ten sposób mechanizmy rządzące ludzką mentalnością w porewolucyjnej rzeczywistości. Jego utwory, jakkolwiek utrzymane w tona­cji groteskowej, są swoistą formą protestu wobec politycznej manipulacji w języku. Fenomenu Zoszczenki nie sposób rozpatrywać z pominięciem przedstawionego fragmentu rzeczywistości językowej czy też w oderwaniu od czasów, w których przyszło mu tworzyć.
Machine Learning Bolsters Evidence That D1, Nef, and Tat Influence HIV Reservoir Dynamics
Authors: Cannon LaMont , Fehrman Sophia , Pinzone Marilia , Weissman Sam , O'Doherty Una 
Published: January 2024

Background: The primary hurdle to curing HIV is due to the establishment of a reservoir early in infection. In an effort to find new treatment strategies, we and others have focused on understanding the selection pressures exerted on the reservoir by studying how proviral sequences change over time.
Methods: To gain insights into the dynamics of the HIV reservoir we analyzed longitudinal near full-length sequences from 7 people living with HIV between 1 and 20 years following the initiation of antiretroviral treatment. We used this data to employ Bayesian mixed effects models to characterize the decay of the reservoir using single-phase and multiphasic decay models based on near full-length sequencing. In addition, we developed a machine-learning approach utilizing logistic regression to identify elements within the HIV genome most associated with proviral decay and persistence. By systematically analyzing proviruses that are deleted for a specific element, we gain insights into their role in reservoir contraction and expansion.
Results: Our analyses indicate that biphasic decay models of intact reservoir dynamics were better than single-phase models with a stronger statistical fit. Based on the biphasic decay pattern of the intact reservoir, we estimated the half-lives of the first and second phases of decay to be 18.2 (17.3 to 19.2, 95%CI) and 433 (227 to 6400, 95%CI) months, respectively.
In contrast, the dynamics of defective proviruses differed favoring neither model definitively, with an estimated half-life of 87.3 (78.1 to 98.8, 95% CI) months during the first phase of the biphasic model. Machine-learning analysis of HIV genomes at the nucleotide level revealed that the presence of the splice donor site D1 was the principal genomic element associated with contraction. This role of D1 was then validated in an in vitro system. Using the same approach, we additionally found supporting evidence that HIV nef may confer a protective advantage for latently infected T cells while tat was associated with clonal expansion.
Conclusions: The nature of intact reservoir decay suggests that the long-lived HIV reservoir contains at least 2 distinct compartments. The first compartment decays faster than the second compartment. Our machine-learning analysis of HIV proviral sequences reveals specific genomic elements are associated with contraction while others are associated with persistence and expansion. Together, these opposing forces shape the reservoir over time.
Long-term patterns and mechanisms of plant invasions in forests: the role of forest age and land-use history
Authors: Jones Chad C. , Yamamoto Matthew H. 
Published: January 2024

Abstract
It has become increasingly apparent that even mature forests are susceptible to plant invasions. However, invasive plants are often more abundant in younger forest stands. It is difficult to disentangle possible mechanisms that would explain this pattern due to the scarcity of long-term studies in successional forests. Several mechanisms have been proposed to explain patterns of invasions as forests age, including biotic resistance, window of opportunity, historical legacies, and invasion debt. We explored patterns and potential mechanisms of plant invasions over 70-years in a regenerating forest with different land use histories in the Bolleswood Natural Area, Connecticut, USA. We examined how environmental factors related to colonization patterns of invasive and non-invasive introduced species over time, and whether these patterns were consistent with the proposed mechanisms. Non-invasive introduced species declined rapidly with forest development, while many invasive plants persisted or even increased over time as the forest aged. Colonization was focused in areas that were unforested when the study began, although this declined with time. Dispersal distance, soil conditions, and initial land cover played important roles in patterns of colonization, while the effect of shading was less clear. There was some evidence for each mechanism, but the relative importance of each mechanism was species-dependent, making generalizations about how invasive plants invade forests difficult. We found that land use history impacted invasion more strongly than forest age, but over time even mature forests were slowly being invaded by some species. Thus, invasive species management may be required even in mature forests.
Induction of Bacteriocin Production by Lacticaseibacillus rhamnosus Using the Co-culture Method
Authors: Khundrakpam Matilda , Kulkarni Padmashree , Bordoloi Sreya , Pani Somya 
Published: January 2024

Abstract
Background: - The rise of antibiotic-resistant bacterial strains in the past decade has led to research on the microorganisms in the human gut and their interactions with pathogenic counterparts. The human gut microbiome houses bacteria like Lactobacilli, which produces bioactive metabolites, called bacteriocins which are known for their antimicrobial activity against disease-causing microorganisms. However, their production is limited in monocultures which can be improved by introducing bacteriocinogenic pathogenic strains in the culture. To enhance bacteriocin production, we have co-cultured Lacticaseibacillus rhamnosus with Staphylococcus aureus, a pathogenic inducer strain in different media like MRS, proso millet modified media (PmMRS) [1], and foxtail millet modified media (FmMRS) [2].
Results: - Antimicrobial assays conducted on bacteriocin extracts revealed potent inhibitory effects against prevalent food-borne pathogenslike Staphylococcus aureus (MTCC[3] 1430), Shigella flexneri (MTCC1457) and Enterobacter cloacae (MTCC 509). The SEM analysis of the co-cultures corresponded to the results from the antimicrobial assay. The bacteriocin extract was analyzed using SDS-PAGE and MALDI-TOF analysis and it exhibited 58% sequence similarity with a translocase protein in Zymomonas mobilis subsp. Mobilis (ATCC31821) and 20% sequence similarity with a bioactive protein produced by Lactiplantibacillus plantarum WCFS5. Encapsulation of the extract in chitosan-based nanoparticles was pursued to enhance its antimicrobial effectiveness.
Conclusion: - While potential applications against foodborne pathogens and antibiotic-resistant bacteria are promising, further research, including purification and delivery optimization, is imperative for practical implementation. This work sheds light on harnessing microbial interactions and bioactive compounds for addressing antibiotic resistance challenges.
Comparative Research on Monitoring Methods for Nitrate Nitrogen Leaching in Tea Plantation Soils
Authors: zheng shenghong , Chai Hongling , Ning Qiuyan , Cheng Chen , He Weizhong , Shu Zaifa , Ni Kang , Ruan Jianyun 
Published: January 2024

Abstract
Background and aims Great concern has long been raised about nitrate leaching in cropland due to its possible environmental side effects in ground water contamination. we conducted a comparative study on monitoring methods for nitrate N leaching in tea plantation soils.Methods Here we employed two common techniques to measure nitrate leaching in tea plantation soils in subtropical China. Using drainage lysimeter as a reference method, the adaptability of estimating drainage and nitrate leaching by combining the water balance equation with the suction cup technique was investigated.Results The final cumulative leachate volume for the calculated and measured method was 721.43 mm and 729.92 mm respectively during the study period. Meanwhile, The cumulative nitrate leaching loss from the lysimeter and suction cup-based method was 47.45 kg ha− 1 and 43.58 kg ha− 1 under lysimeter nitrate concentrations ranging from 7 mg L− 1 to 13 mg L− 1, 156.28 kg ha− 1 and 79.95 kg ha− 1 under lysimeter nitrate concentrations exceeding 13 mg L− 1.Conclusion The suction cup-based method could be an alternative way of monitoring nitrate leaching loss within a certain range of nitrate concentrations in leachate. Besides, lower results occurred in suction cup samplers due to lack of representative samples which mainly leached via preferential flow when in strong leaching events. Thus, it is advisable to increase sampling frequency under such special conditions. The results of this experiment can serve as a reference and guidance for the application of ceramic cups in monitoring nitrogen and other nutrient-ion leaching in tea plantation soils.
Apples, Oranges, Vanilla, and Myths: Adolescents’ Discourse on Alcohol and Substance Use in Kenya
Authors: Musyoka Catherine Mawia , Okunoren Oladoyin , Klein Elizabeth K. , Byansi William , Amulundu Maurice Kalande , Mathai Muthoni , Crea Thomas M 
Published: January 2024

Abstract
Background and Purpose: Alcohol and substance use disorders (ASUD) are highly prevalent among adolescents in sub-Saharan Africa and co-occur with mental health disorders. This study aims to understand the adolescents’ awareness about and attitudes towards ASUD and mental health literacy, with the long-term goal of informing the development of a sustainable intervention.
Methods: An exploratory qualitative study included 144 adolescents (aged 15-19) in 12 focus group discussions (FGDs). Participants were purposely sampled from three informal settlements in Nairobi and Kiambu counties in Kenya. Separate FGDs were conducted for boys and girls in two age groups (15-17 and 18-19). FGDs were audio recorded, transcribed, and translated into English when needed and analyzed using deductive thematic content analysis.
Results: Adolescents demonstrated both knowledge of facts and “myths” about mental health and ASUD. They believed ASUDs were significant community problems but at the same time perceived options that some substances like shisha (Hookah) as harmless. They also acknowledge that environmental factors, like financial and social pressures, increase the risk of ASUD. Adolescents made the connection that family members’ alcohol and substance use (ASU) and easy accessibility of alcohol and other substances of abuse in the community present a further risk for substance use. Adolescents highlighted that future interventions should include mental health and substance use education (risks and coping strategies), and access to non-stigmatizing support.
Conclusions and Implications: Study Results showed that adolescents are aware of ASUD in their communities and identified a combination of community-based support and virtual engagement via mobile technology which they viewed as useful resources possessing the potential for effective ASU prevention and intervention among adolescents.
Primary cutaneous anaplastic large-cell lymphoma resembling space infection: a case report
Authors: Yan Xiaohan , Ren Wenhao , Li Shaoming , Zhu Zhuang , Gao Ling , Zhi Keqian 
Published: January 2024

Abstract
Background: Primary cutaneous anaplastic large-cell lymphoma (PC-ALCL) is a rare T-cell lymphoma belonging to the CD30+ T-cell lymphoproliferative disorders. The case of PC-ALCL in the temporal and parotid gland region is exceedingly rare. Herein, we report a case of PC-ALCL involving the temporal and parotid gland region mimicking maxillofacial space infection.
Case presentation: A 78-year-old woman presented to maxillofacial surgery service with a 6-month history of swelling and pain in the left side of her face. The patient underwent incision and drainage, and we unexpectedly found no pus in the lesion area. Incisional biopsy showed necrosis and extensive involvement of the left temples by a diffuse infiltrate containing large, atypical cells. The tumor cells were positive for CD30, CD3, and Ki67, and negative for ALK (SP8). After considering these findings, a diagnosis of PC-ALCL was rendered. The patient was admitted to the lymphoma department for systemic chemotherapy and no relapse occurred during a follow-up period of three months.
Conclusions: This report suggests that if there are suspicious intraoperative manifestations, carrying out a biopsy simultaneously, using HE staining, comprehensive IHC panels, and combining them with a systematic approach is essential to diagnosing ALCL to prevent misdiagnosis.
Salt intake among Iranian population: national and subnational report from STEPS 2021
Authors: Nosratinia Nasim , Azadnajafabad Sina , Masinaei Masoud , Golestani Ali , Ghamari Seyyed-Hadi , Abbasi-Kangevari Mohsen , Rezaei Negar , Khosravi Sepehr , Rezaei Shahabeddin , Ahmadi Naser , Kazemi Ameneh , Ghasemi Erfan , Farzi Yosef , Rashidi Mohammad-Mahdi , Yoosefi Moein , Rezaei Nazila , Nasserinejad Maryam , Haghshenas Rosa , Fateh Sahar Mohammadi , Keykhaei Mohammad , Moghimi Mana , Mehr Elmira Foroutan , Rankohi Azadeh Momen Nia , Djalalinia Shirin , Farzadfar Farshad 
Published: January 2024

Abstract
High salt intake is a major risk factor for non-communicable diseases, resulting in numerous deaths and disability-adjusted life-years worldwide. The study aimed to analyze data from a 2021 nationwide survey of 25,202 Iranian adults, investigating daily salt intake. Participants were randomly chosen by a systematic proportional size cluster sampling. All of them completed questionnaires and their anthropometric and physical measurements were taken. Using Tanaka method and necessary equations, spot urine samples were taken to estimate 24-hour urine sodium and evaluate daily sodium intake in grams. The mean amount of salt intake was 9.71g (95% CI: 9.66–9.76) in 2021. Furthermore, 98.0% of participants consumed more than 5g of salt daily. Salt intake in men was higher than in women (9.95g (95% CI: 9.87–10.3) vs 9.51g (9.44–9.58) daily. Rural areas’ residents and people with lower years of schooling consumed higher levels of salt per day, 10.02g (9.96–10.07) and 9.99g (9.88–10.1), respectively. Mean salt consumption in married people was higher than in single individuals by 0.37g per day. Salt consumption was higher in obese participants in comparison to people with normal BMI (10.16g (10.06–10.26) vs 8.72g (8.43–9.01)). The risk of high salt consumption was significantly lower in hypertensive participants than normotensive ones (adjusted OR = 0.467, 95% CI: 0.345–0.631), as well as being aware of hypertension in hypertensive patients (adjusted OR = 0.338, 95% CI: 0.190–0.603). Iranians’ salt intake was nearly double the WHO-recommendation. Approved effective interventions must be considered to lower salt consumption in Iran like food labeling, educating people, and using salt substitutes.