bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors Associated with Reliable Contact Tracing During the 2021 Ebola Virus Disease Outbreak in Guinea
Authors: Keita Mory , Cherif Ibrahima Sory , Polonsky Jonathan A. , Boland Samuel T. , Kandako Youba , Cherif Mahamoud Sama , Kourouma Mamadou , Kamano Aly Antoine , Bah Houssainatou , Fofana Ibrahima Sory , Ki-zerbo Georges Alfred , Dagron Stephanie , Chamla Dick , Gueye Abdou Salam , Keiser Olivia 
Published: February 2024

Abstract
Background
In 2021, an Ebola virus disease (EVD) outbreak was declared in Guinea, linked to persistent virus from the 2014–2016 West Africa Epidemic. This paper analyzes factors associated with contact tracing reliability (defined as completion of a 21-day daily follow-up) during the 2021 outbreak, and transitively, provides recommendations for enhancing contact tracing reliability in future.

Methods
We conducted a descriptive and analytical cross-sectional study using multivariate regression analysis of contact tracing data from 1071 EVD contacts of 23 EVD cases (16 confirmed and 7 probable).

Results
Findings revealed statistically significant factors affecting contact tracing reliability. Unmarried contacts were 12.76× more likely to miss follow-up than those married (OR = 12.76; 95% CI [3.39–48.05]; p < 0.001). Rural-dwelling contacts had 99% lower odds of being missed during the 21-day follow-up, compared to those living in urban areas (OR = 0.01; 95% CI [0.00–0.02]; p < 0.01). Contacts who did not receive food donations were 3× more likely to be missed (OR = 3.09; 95% CI [1.68–5.65]; p < 0.001) compared to those who received them. Contacts in health areas with a single team were 8× more likely to be missed (OR = 8.16; 95% CI [5.57–11.96]; p < 0.01) than those in health areas with two or more teams (OR = 1.00; 95% CI [1.68–5.65]; p < 0.001). Unvaccinated contacts were 30.1× more likely to be missed compared to vaccinated contacts (OR = 30.1; 95% CI [5.12–176.83]; p < 0.001).

Conclusion
Findings suggest that contact tracing reliability can be significantly influenced by various demographic and organizational factors. Considering and understanding these factors—and where possible addressing them—may be crucial when designing and implementing contact tracing strategies during future outbreaks in low-resource settings.
Upregulation of lnc-FOXD2-AS1, CDC45, and CDK1 in patients with primary non-M3 AML is associated with a worse prognosis
Authors: Manoochehrabadi Saba , Talebi Morteza , Pashaiefar Hossein , Ghafouri-Fard Soudeh , Vaezi Mohammad , Omrani Mir Davood , Ahmadvand Mohammad 
Published: February 2024

AbstractAcute myeloid leukemia (AML) is a heterogeneous hematologic malignancy with an unfavorable outcome. The present research aimed to identify novel biological targets for AML diagnosis and treatment. In this study, we performed an in-silico method to identify antisense RNAs (AS-RNAs) and their related co-expression genes. GSE68172 was selected from the AML database of the Gene Expression Omnibus and compared using the GEO2R tool to find DEGs. Antisense RNAs were selected from all the genes that had significant expression and a survival plot was drawn for them in the GEPIA database, FOXD2-AS1 was chosen for further investigation based on predetermined criteria (logFC ≥|1| and P < 0.05) and its noteworthy association between elevated expression level and a marked reduction in the overall survival (OS) in patients diagnosed with AML. The GEPIA database was utilized to investigate FOXD2-AS1-related co-expression and similar genes. The Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analysis and gene ontology (GO) function analysis of the mentioned gene lists were performed using the DAVID database. The protein–protein interaction (PPI) network was then constructed using the STRING database. Hub genes were screened using Cytoscape software. Pearson correlation analysis was conducted using the GEPIA database to explore the relationship between FOXD2-AS1 and the hub genes. The transcription of the selected coding and non-coding genes, including FOXD2-AS1, CDC45, CDC20, CDK1, and CCNB1, was validated in 150 samples, including 100 primary AML non-M3 blood samples and 50 granulocyte colony stimulating factor (G-CSF)-mobilized healthy donors, using quantitative Real-Time PCR (qRT-PCR). qRT-PCR results displayed significant upregulation of lnc-FOXD2-AS1, CDC45, and CDK1 in primary AML non-M3 blood samples compared to healthy blood samples (P = 0.0032, P = 0.0078, and P = 0.0117, respectively). The expression levels of CDC20 and CCNB1 were not statistically different between the two sets of samples (P = 0.8315 and P = 0.2788, respectively). We identified that AML patients with upregulation of FOXD2-AS1, CDK1, and CDC45 had shorter overall survival (OS) and Relapse-free survival (RFS) compared those with low expression of FOXD2-AS1, CDK1, and CDC45. Furthermore, the receiver operating characteristic (ROC) curve showed the potential biomarkers of lnc -FOXD2-AS1, CDC45, and CDK1 in primary AML non-M3 blood samples. This research proposed that the dysregulation of lnc-FOXD2-AS1, CDC45, and CDK1 can contribute to both disease state and diagnosis as well as treatment. The present study proposes the future evolution of the functional role of lnc-FOXD2-AS1, CDC45, and CDK1 in AML development.
Real-world incidence and risk factors of bortezomib-related cardiovascular adverse events in patients with multiple myeloma
Authors: Jang Bitna , Jeong Jonghyun , Heo Kyu-Nam , Koh Youngil , Lee Ju‑Yeun 
Published: February 2024

Abstract
Background
Although most studies on the cardiovascular toxicity of proteasome inhibitors have focused on carfilzomib, the risk of cardiotoxicity associated with bortezomib remains controversial. This study aimed to evaluate the incidence and risk factors of cardiovascular adverse events (CVAEs) associated with bortezomib in patients with multiple myeloma in a real-world setting.

Methods
This cross-sectional study included patients who were treated with bortezomib at a tertiary hospital in South Korea. CVAEs, defined as hypertension, arrhythmia, heart failure, myocardial infarction, pulmonary arterial hypertension, angina, and venous thromboembolism, were detected using cardiac markers, ECG, echocardiography, medications, or documentation by clinicians. The patients were observed for at least 6 months and up to 2 years after starting bortezomib administration.

Results
Among the 395 patients, 20.8% experienced CVAEs of any grade, and 14.7% experienced severe adverse events. The median onset time for any CVAE was 101.5 days (IQR, 42–182 days), and new-onset/worsened hypertension was the most prevalent CVAE. The risk of CVAEs increased in patients with a body mass index lower than 18.5 (adjusted HR (aHR) 3.50, 95% confidence interval (CI) 1.05-11.72), light chain (1.80, 1.04-3.13), and IgD (4.63, 1.06-20.20) as the multiple myeloma subtype, baseline stroke (4.52, 1.59-12.80), and hypertension (1.99, 1.23-3.23). However, CVAEs did not significantly affect the 2-year overall survival and progression-free survival.

Conclusion
Approximately 15% of the Korean patients treated with bortezomib experienced severe CVAEs. Thus, patients, especially those with identified risk factors, should be closely monitored for CVAE symptoms during bortezomib treatment.
Assessing the quality of European Impact Assessments
Authors: Danciu Diana-Maria , Martens Laura , Marneffe Wim 
Published: February 2024

AbstractThis paper explores the possibility of developing a framework to assess the quality of Impact Assessments (IAs) by examining the common elements found in the existent academic literature around this concept, the stocktaking exercises carried out by the European institutions and the opinions of the Regulatory Scrutiny Board. At this intersection, we find that diversity in the interpretation and application of the guidelines is not only acceptable but also necessary in tailoring IAs to the needs they represent. Our findings are relevant because a universal framework that avoids focusing solely on assessing quality not only will provide much-needed coherence in this field but will also raise awareness about the normality of variability in the application of any European Union guidelines, thus reflecting the inherent nature of the IAs.
Acquitted on the Benefit of Doubt … but not Proven Innocent! The Judgment of the German Federal Constitutional Court on the Next Generation EU Program
Authors: Anagnostaras Georgios 
Published: February 2024

AbstractUntil recently, the recognition to the European Union of the capacity to borrow from capital markets for spending purposes was considered almost inconceivable without a treaty amendment. When borrowing for spending was authorized under the Next Generation EU program to support the recovery of member states from the unprecedented consequences of the coronavirus, it was immediately faced with the suspicion that the pandemic was being used as a pretext to promote the creation of a fiscal and transfer union by the back door in violation of the principle of conferral. In its NGEU judgment, the German Federal Constitutional Court concluded that the authorization to borrow under the program could not be considered ultra vires. However, the ambiguous and controversial reasoning of the Constitutional Court gives rise to uncertainty as to whether the funding and financing model introduced by the recovery program could be used again in the future, beyond the exceptional circumstances of the pandemic. At the same time, it appears that, in this case, the Constitutional Court applied a considerably more restrained version of its ultra vires review compared to its recent case law on the asset purchase programs of the European Central Bank.
Using local ecological knowledge to determine the status of Cantor's giant softshell turtle Pelochelys cantorii in Kerala, India
Authors: Jain Ayushi , Akshay V.A. , Deepak V. , Das Abhijit , Barnes Paul , Tapley Benjamin , Cavada-Blanco Francoise 
Published: February 2024

AbstractThe Critically Endangered Cantor's giant softshell turtle Pelochelys cantorii is a freshwater turtle found in South and Southeast Asia. Its population is declining because of habitat destruction and alteration, and hunting for its meat. Data on the species’ ecology, behaviour, population size, distribution and threats are limited, and previous surveys undertaken in India have failed to detect individuals in the wild. This lack of data hinders strategic conservation planning. Ecologists and conservationists increasingly utilize local ecological knowledge to determine the status and gain insights into the ecology of threatened and rare species that are difficult to detect in field studies. To examine the historical and current occurrence of Cantor's giant softshell turtle, we conducted community interviews along the Chandragiri River in Kerala, India. With data from these interviews, we identified multiple sites where the species continues to occur. Older respondents and those that used the river for fishing and irrigation were more likely to report sightings of the species. Our findings also improved knowledge about the turtles’ seasonal and diel activity patterns. A network of key informants identified through the interviews provided information on turtle bycatch, sightings and nesting. This network is being utilized for the continued monitoring of the species and could help in devising evidence-based management strategies for softshell turtles in India. These methods can also be adopted more widely for other threatened species of freshwater turtles globally.
Gender and the Displaced Worker in Contemporary France: Women, Mobility, and Economic Restructuring Beyond the Industrial Heartlands
Authors: Clarke Jackie , Gallot Fanny 
Published: February 2024

AbstractA considerable proportion of the research conducted within the developing field of deindustrialisation studies has focused on the loss of work in industrial closures, and on the attachments that long-serving workers feel to their former workplace. This article focuses instead on the phenomenon of constrained mobility which often occurs as companies restructure and workers are offered a choice between redundancy or relocation to another site. Steven High (2003) has examined the ‘transplanted identities’ of male workers who had moved repeatedly as plants downsized and closed across the American rust belt, highlighting a group who styled themselves as the ‘I-75 gypsies’ (after the interstate highway that runs through Michigan and Ohio). Forging a new identity articulated in terms of mobility rather than place, these men constructed a new version of heroic working-class masculinity as they moved from site to site. This article draws on a case study of the Moulinex domestic appliance company in north western France to examine how such mobility has been experienced by women workers in a region beyond the industrial heartlands. In doing so, it considers the particular relationship to place that was constructed as companies like Moulinex established factories in rural regions of France after the Second World War and the implications of this for work-based identities. The article highlights the intersecting effects of age and gender, the significance of the gendered division of labour for women's experiences of mobility, and the extent to which identities were reshaped as women moved to stay in work.
Botany and national identities: The Tokyo Cherry
Authors: Kuitert Wybe 
Published: February 2024

ArgumentWhen Japan faced the world after the collapse of its feudal system, it had to invent its own modern identity in which the Tokyo Cherry became the National Flower. Despite being a garden plant, it received a Latin scientific species name as if it was an endemic species. After Japan’s colonial conquest of Korea, exploring the flora of the peninsula became part of imperial knowledge practices of Japan. In the wild, a different cherry was discovered in Korea that was proposed as the endemic parent of the Tokyo Cherry, supporting imperialist policies. Following Japan’s defeat after the Pacific War, South Korea in turn entered its search for cultural identity. The supposed parent of the Tokyo Cherry was now successfully acclaimed as the parent species of the colonial oppressor’s Tokyo Cherry and named the King Cherry. Such scientific practice into cherries smoothly intertwined with nationalism and its legacy continues to interfere with research today.
Daydreaming and grandiose delusions: development of the Qualities of Daydreaming Scale
Authors: Isham Louise , Loe Bao Sheng , Hicks Alice , Wilson Natalie , Bentall Richard P. , Freeman Daniel 
Published: February 2024

AbstractBackground:Daydreaming may contribute to the maintenance of grandiose delusions. Repeated, pleasant and vivid daydreams about the content of grandiose delusions may keep the ideas in mind, elaborate the details, and increase the degree of conviction in the delusion. Pleasant daydreams more generally could contribute to elevated mood, which may influence the delusion content.Aims:We sought to develop a brief questionnaire, suitable for research and clinical practice, to assess daydreaming and test potential associations with grandiosity.Method:798 patients with psychosis (375 with grandiose delusions) and 4518 non-clinical adults (1788 with high grandiosity) were recruited. Participants completed a daydreaming item pool and measures of grandiosity, time spent thinking about the grandiose belief, and grandiose belief conviction. Factor analysis was used to derive the Qualities of Daydreaming Scale (QuOD) and associations were tested using pairwise correlations and structural equation modelling.Results:The questionnaire had three factors: realism, pleasantness, and frequency of daydreams. The measure was invariant across clinical and non-clinical groups. Internal consistency was good (alpha-ordinals: realism=0.86, pleasantness=0.93, frequency=0.82) as was test–retest reliability (intra-class coefficient=0.75). Daydreaming scores were higher in patients with grandiose delusions than in patients without grandiose delusions or in the non-clinical group. Daydreaming was significantly associated with grandiosity, time spent thinking about the grandiose delusion, and grandiose delusion conviction, explaining 19.1, 7.7 and 5.2% of the variance in the clinical group data, respectively. Similar associations were found in the non-clinical group.Conclusions:The process of daydreaming may be one target in psychological interventions for grandiose delusions.
New insights on what leads bilinguals to be able to name some pictures only in their nondominant language: Immersion, dominance reversal, and balanced bilingualism
Authors: Neveu Anne , Gollan Tamar H. 
Published: February 2024

AbstractObjective:The present study asked if bilinguals who are immersed in their nondominant language are more likely to know some words only in their nondominant language.Method:The either-language scoring benefit (ELSB) reflects how many more points bilinguals get when credited for pictures named regardless of which language is used. We asked if the ELSB varies with self-rated proficiency level of the nondominant language in young English-dominant (n = 68) compared to Spanish-dominant (n = 33) bilinguals, and in older English-dominant (n = 36) compared to Spanish-dominant (n = 32) bilinguals. All bilinguals were immersed in English (in the USA) at the time of testing.Results:Spanish-dominant bilinguals showed a larger ELSB than English-dominant bilinguals (in both young and older groups), but simple correlations showed that the degree of Spanish dominance was associated with a higher ELSB only in young bilinguals. Additionally, the ELSB was larger for bilinguals with more years of immersion and for more balanced bilinguals, whether measured by naming scores or self-rated balance (in both age groups). Nearly half (n = 14/33) of the young bilinguals who said they were Spanish-dominant scored higher in English than in Spanish, and on average these participants had similar naming scores in English and Spanish.Conclusions:Either-language scoring benefits bilinguals with higher proficiency level in the nondominant language, which is more likely in bilinguals with extended immersion in the nondominant language, who also tend to be more balanced bilinguals, and for young adult bilinguals who may be in the process of a switch in which language is dominant.
The expansion and remaining suitable areas of global oil palm plantations
Authors: Zhao Qiang , Yu Le , Li Xiyu , Xu Yidi , Du Zhenrong , Kanniah Kasturi , Li Chengxiu , Cai Wenhua , Lin Hui , Peng Dailiang , Zhang Yongguang , Gong Peng 
Published: February 2024

Abstract

Non-technical summary
Oil palm has been criticized for being an environmentally unfriendly oil crop. In recent decades, oil palm plantations have extended into conservation landscapes, causing severe environmental damage and harming biodiversity. Nevertheless, oil palm remains a highly productive oil crop from which most of the world's vegetable oil is produced. Therefore, measuring the environmental impact of oil palm plantations and identifying suitable land to support its sustainable development is crucial.

Technical summary
To meet the rising global palm oil demand sustainably, we tracked annual land cover changes in oil palm plantation and mapped areas worldwide suitable for sustainable oil palm cultivation. From 1982 to 2019, 3.6 Mha of forests were converted to oil palm plantations. Despite a recent decline in overall conversion, the shift from forest to oil palm plantations has become increasingly more common over the last decade, rising from 14.1 to 34.5% between 2009 and 2019. During 1982–2019, 2.23 Mha of peatland and 0.1 Mha of protected areas were converted for oil palm plantations. The potential sustainable land amounts to 103.5–317.9 Mha (Asia: 44.6–105.1 Mha, Africa: 34.7–96.4 Mha, and Latin America: 35.2–116.5 Mha). Future oil palm expansion is anticipated to take place in countries like Brazil, Nigeria, Colombia, Indonesia, Ivory Coast, the Democratic Republic of the Congo, and Ghana, where more sustainable land is available for cultivation. Malaysia, on the other hand, is about to exceed the area of sustainable cultivation, and further expansion is not recommended. These findings can advance our understanding of the environmentally damaging impacts of oil palm and enhance the feasibility of sustainable oil palm development.

Social media summary
How should suitable land be chosen for the establishment of oil palm plantations to support the sustainable development of the oil palm plantation industry?
More than meets the ITT: A guide for anticipating and investigating nonsignificant results in survey experiments
Authors: Kane John V. 
Published: February 2024

AbstractSurvey experiments often yield intention-to-treat effects that are either statistically and/or practically “non-significant.” There has been a commendable shift toward publishing such results, either to avoid the “file drawer problem” and/or to encourage studies that conclude in favor of the null hypothesis. But how can researchers more confidently adjudicate between true, versus erroneous, nonsignificant results? Guidance on this critically important question has yet to be synthesized into a single, comprehensive text. The present essay therefore highlights seven “alternative explanations” that can lead to (erroneous) nonsignificant findings. It details how researchers can more rigorously anticipate and investigate these alternative explanations in the design and analysis stages of their studies, and also offers recommendations for subsequent studies. Researchers are thus provided with a set of strategies for better designing their experiments, and more thoroughly investigating their survey-experimental data, before concluding that a given result is indicative of “no significant effect.”
Seismic Evidence for Craton Formation by Underplating and Development of the MLD
Authors: Boyce Alistair , Bodin Thomas , Durand Stéphanie , Soergel Dorian , Debayle Eric 
Published: February 2024

AbstractInconsistencies between observations from long and short period seismic waves and geochemical data mean craton formation and evolution remains enigmatic. Specifically, internal layering and radial anisotropy are poorly constrained. Here, we show that these inconsistencies can be reconciled by inverting cratonic Rayleigh and Love surface wave dispersion curves for shear‐wave velocity and radial anisotropy using a flexible Bayesian scheme. This approach requires no explicit vertical smoothing and only adds anisotropy to layers where required by the data. We show that all cratonic lithospheres are comprised of a positively radially anisotropic upper layer, best explained by Archean underplating, and an isotropic layer beneath, indicative of two‐stage formation. Within the positively radially anisotropic upper layer, we find a variable amplitude low velocity zone within 9 of 12 cratons studied, that is well correlated with observed Mid‐Lithospheric Discontinuities (MLDs). The MLD is best explained by metasomatism after craton formation.