bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge and attitudes of primary care physicians regarding childhood hearing loss in Malaysia
Authors: Mazlan Rafidah , Othman Sagshafraa 
Published: December 2023

Background
Childhood hearing loss is a significant health concern. Early identification and intervention are essential to maximize hearing potential and developmental outcomes, with primary care physicians (PCPs) playing a pivotal role in this process.

Objectives
This study aimed to assess PCPs’ knowledge and attitudes toward childhood hearing loss, investigate the association between knowledge and attitudes, and examine the influence of demographic factors on PCPs’ knowledge and attitudes towards childhood hearing loss.

Methods
This cross-sectional study was conducted from 30 November 2017 to 30 July 2018 at three public health clinics in Malaysia, specifically in the Federal Territory of Kuala Lumpur, Selangor, and Terengganu. A self-administered questionnaire assessed PCPs’ knowledge of general facts, diagnosis and intervention, and risk factors for childhood hearing loss. Additionally, the questionnaire evaluated PCPS’ attitudes across cognitive, affective, and behavioural domains regarding childhood hearing loss.

Results
Most participants lacked sufficient knowledge about childhood hearing loss, with 61.4% not seeing it as a major health issue. Almost half (45.9%) didn’t know that children with hearing loss can succeed in regular schools, and 78% were unaware that hearing aids don’t fully restore normal hearing. Participants’ awareness of risk factors varied widely, ranging from 24.6% to 90.3%. Despite these knowledge gaps, participants generally had positive attitudes towards childhood hearing loss, especially in cognitive and behavioural aspects. The study found a strong positive link between knowledge and attitudes, but demographic factors didn’t significantly affect them.

Conclusions
This study highlights the urgent need to address knowledge gaps among Malaysian PCPs regarding childhood hearing loss. While these knowledge gaps exist, PCPs’ positive attitudes form a foundation for developing targeted educational interventions to improve PCPs’ knowledge and skills in managing childhood hearing loss. Collaborative efforts are essential to translate these findings into meaningful improvements in paediatric audiological care.
Untargeted metabolomics analysis reveals the metabolic disturbances and exacerbation of oxidative stress in recurrent spontaneous abortion
Authors: Wu AiNing , Zhao YanHui , Yu RongXin , Zhou JianXing , Tuo Ya 
Published: December 2023

Background
Recurrent spontaneous abortion (RSA) is characterized by the occurrence of two or more consecutive spontaneous abortions, with a rising prevalence among pregnant women and significant implications for their physical and mental well-being. The multifaceted etiology of RSA has posed challenges in unraveling the molecular mechanisms underlying that underlie its pathogenesis. Oxidative stress and immune response have been identified as pivotal factors in the development of its condition.

Methods
Eleven serum samples from healthy pregnant women and 17 from RSA were subjected to liquid chromatography/mass spectrometry (LC-MS) analysis. Multivariate statistical analysis was employed to excavate system-level characterization of the serum metabolome. The measurement of seven oxidative stress products, namely superoxide dismutase (SOD), catalase (CAT), malonaldehyde (MDA), glutathione (GPx), glutathione peroxidase (GSH), oxidized glutathione (GSSG), heme oxygenase (HO-1), was carried out using ELISA.

Results
Through the monitoring of metabolic and lipid alternations during RSA events, we have identified 816 biomarkers that were implicated in various metabolic pathways, including glutathione metabolism, phosphonate and phosphinate metabolism, nucleotide metabolism, sphingolipid metabolism, lysine degradation and purine metabolism, etc. These pathways have been found to be closely associated with the progression of the disease. Our finding indicated that the levels of MDA and HO-1 were elevated in the RSA group compared to the control group, whereas SOD, CAT and GPx exhibited a contrary pattern. However, no slight difference was observed in GSH and GSSG levels between the RSA group and the control group.

Conclusion
The manifestation of RSA elicited discernible temporal alternations in the serum metabolome and biochemical markers linked to the metabolic pathways of oxidative stress and immune response. Our investigation furnished a more comprehensive analytical framework encompassing metabolites and enzymes associated with oxidative stress. This inquiry furnished a more nuanced comprehension of the pathogenesis of RSA and established the ground work for prognostication and prophylaxis.
The development of physical characteristics in adolescent team sport athletes: A systematic review
Authors: Tingelstad Lars M. , Raastad Truls , Till Kevin , Luteberget Live S. 
Published: December 2023

Background
Physical development during adolescence is crucial for athletes in team sports, as it prepares them for the high sport demands at the senior level. While physical development in non-athletes are well-documented, a comprehensive understanding of adolescent athletes’ development, including the potential effects of team sports participation and training load, is lacking.

Objectives
The study aimed to investigate the development of physical characteristics in team sport athletes during adolescence (12–20 years) and explore the impact of training load.

Methods
A systematic search of the databases PubMed, SPORTDiscus and Web of Science were conducted combining keywords related to physical characteristics, youth athletes, team sport and study design. Criteria for inclusion were: (1) team sport athletes aged 12–20 years, (2) cross-sectional or longitudinal designs investigating physical characteristics, (3) comparisons across different age groups, (4) peer-reviewed original article, (5) written in English, and (6) available results from physical testing. Results were normalized and weighted based on sample size.

Results
176 eligible articles were identified. The results showed consistent annual improvement in most physical characteristics from 12 to 16 years for both sexes (e.g., boys: lower body strength 14.3%; intermittent endurance 11%; countermovement jump height 6.7%; change of direction 2.8%; 30 m sprint 3.6%, and girls: lower body strength 9.4%; intermittent endurance 12.1%; countermovement jump 4.7%; change of direction 3.3%; 30 m sprint 1.9%). Only 4 studies investigated the effect of training load on physical development.

Conclusions
Although both sexes consistently improved through adolescence, girls tended to have less pronounced physical development compared to boys, likely due to lower increase in lean mass and limb length. The existing evidence do not definitively establish whether team sports participation, compared to studies examining non-athletes, or training load have an additive effect on physical development during this period.
Dietary magnesium, C-reactive protein and interleukin-6: The Strong Heart Family Study
Authors: Rao Nandana D. , Lemaitre Rozenn N. , Sitlani Colleen M. , Umans Jason G. , Haack Karin , Handeland Veronica , Navas-Acien Ana , Cole Shelley A. , Best Lyle G. , Fretts Amanda M. 
Published: December 2023

Objectives
To examine the associations of dietary Mg intake with inflammatory biomarkers (C-reactive protein (CRP) and interleukin 6 (IL-6)), and the interaction of dietary Mg intake with single nucleotide polymorphism (SNP) rs3740393, a SNP related to Mg metabolism and transport, on CRP and IL-6 among American Indians (AIs).

Methods
This cross-sectional study included AI participants (n = 1,924) from the Strong Heart Family Study (SHFS). Mg intake from foods and dietary supplements was ascertained using a 119-item Block food frequency questionnaire, CRP and IL-6 were measured from blood, and SNP rs3740393 was genotyped using MetaboChip. Generalized estimating equations were used to examine associations of Mg intake, and the interaction between rs3740393 and dietary Mg, with CRP and IL-6.

Results
Reported Mg intake was not associated with CRP or IL-6, irrespective of genotype. A significant interaction (p-interaction = 0.018) was observed between Mg intake and rs3740393 on IL-6. Among participants with the C/C genotype, for every 1 SD higher in log-Mg, log-IL-6 was 0.04 (95% CI: -0.10 to 0.17) pg/mL higher. Among participants with the C/G genotype, for every 1 SD higher in log-Mg, log-IL-6 was 0.08 (95% CI: -0.21 to 0.05) pg/mL lower, and among participants with the G/G genotype, for every 1 SD higher in log-Mg, log-IL-6 was 0.19 (95% CI: -0.38 to -0.01) pg/mL lower.

Conclusions
Mg intake may be associated with lower IL-6 with increasing dosage of the G allele at rs3740393. Future research is necessary to replicate this finding and examine other Mg-related genes that influence associations of Mg intake with inflammation.
Predictors of triage pain assessment and subsequent pain management among pediatric patients presenting to the emergency department
Authors: Valani Rahim , Kassam Fazila , Jose Shauna , Hanna Mario , Sharma Tanmay , Sriranjan Jhanahan , Bhathena Yazad , Boodoo Umairah , Agarwal Aashna , Upadhye Suneel 
Published: December 2023

Background
Pediatric patients with pain of various causes present to the emergency department. Appropriate assessment and management of pain are important aspects of emergency department treatment. However, only a few studies have identified the predictors of both outcomes. This study aimed to evaluate the rate of pain assessment at triage and subsequent management and to identify the predictors of each outcome.

Methods
This was a multi-center retrospective study based at five community emergency departments. Pediatric patients (< 18 years) with pain or injury who presented to the emergency department between February 2018 and May 2018 were included. In addition to patient demographics, the initial pain assessment at triage, reason for visit, and time to analgesia were determined. Further, the type and route of analgesia were identified in patients who received analgesia. Univariate and multivariable regression models were used to identify predictors of pain assessment and management.

Results
There were 4,128 patients with an average age of 9.6 years, and 49.1% of them were female. Only 74.2% of the patients underwent assessment for pain at triage, and 18.3% received analgesia. The median time to analgesia was 95 (IQR: 49–154) min. Most patients presented with head/neck (36.1%), upper limb (21.6%), and lower limb (19.9%) pain. The oral route was the most common analgesia delivery method (67.4%), and ibuprofen and acetaminophen were the primary agents used. Younger age, higher acuity, and presenting with head or neck pain were independent predictors of pain assessment at triage, while children 3–5 years and those with lower extremity pain were more likely to receive analgesia.

Conclusion
Although pain assessment at triage has improved in pediatric patients, there is still a major deficiency in adequate pain management. Our study highlights predictors of pain assessment and management that can be considered for improved pediatric care.
The Bloomsbury Handbook of Radio, Kathryn Mcdonald and Hugh Chignell (eds) (2023)
Authors: Medhurst Jamie 
Published: December 2023

Review of: The Bloomsbury Handbook of Radio, Kathryn Mcdonald and Hugh Chignell (eds) (2023)
London: Bloomsbury, xiii + 547 pp.,
ISBN 978-1-50138-531-5, h/bk, £126
ISBN 978-1-50138-529-2, e-PDF, £100.80
ISBN 978-1-50138-530-8, e-book, £100.80
Finding of the Amanita phalloides in the Akmola region and its distribution in Kazakhstan
Authors: Fedorenko Vasiliy 
Published: December 2023

The article presents data on a new finding of the Death cap – Amanita phalloides (Vaill. ex Fr.) Link in Kazakhstan. The species were found in two locations in a mixed forest in the vicinity of the Shchuchinsky village near the Shchuchinsk city. This is the first record of the species for the Akmola region and the fourth location in Kazakhstan. Based on the studied specimens, a clarified description of the macroscopic and microscopic characteristics of A. phalloides. Detailed descriptions for specimens from Kazakhstan are provided for the first time. A comparison of the obtained description with literary data did not reveal significant discrepancies. The photographs of the macro- and microcharacteristics of the collected specimens are presented in the article. A number of literary and electronic sources were analyzed, as a result of which a map of the Death cap finds in Kazakhstan and in the adjacent territory of Russia was built. Considering its general distribution, the discovery of the A. phalloides can be expected in other forested areas of the northern and eastern regions of the country in the future. The article discusses the overall distribution of this species in the republic and the likelihood of its appearance as a result of introduction.
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On the occurrence of Sisymbrium orientale (Cruciferae) in Middle Asia
Authors: German Dmitry A. , Ruzimatov Ruzali Yo. , Hoshimov Hushbacht R. 
Published: December 2023

The matter of presence of Sisymbrium orientale in the flora of Middle Asia long known in the region based on the single gathering from Turkmenistan is clarified. Occurrence of the species in the latter country is not confirmed because of incorrect identification of relevant collection which belongs to S. septulatum. At the same time, S. orientale is a novelty for the region based on its recent (2023) finding in Uzbekistan first reported here. Alien character of the gathering is proposed and further spread of the species in the Middle Asia is assumed.
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Therapeutic Endoscopy to the Rescue: EUS Gallbladder Drainage and ESD of a Giant Duodenal Polyp
Authors: Chen Bing , Johal Riya , Abdulsamad Molham 
Published: December 2023

ABSTRACT
The role of endoscopy in the management of traditionally surgical conditions continues to evolve. Endoscopic techniques, including endoscopic mucosal resection and more recently endoscopic submucosal dissection, which remove cancerous and precancerous lesions in the gastrointestinal tract, continue to grow in use. In addition, therapeutic endoscopic ultrasound has evolved to include the management of patients with acute cholecystitis. Here, we present an 83-year-old man with acute calculus cholecystitis, who was considered ineligible for cholecystectomy and had a giant duodenal polyp that obstructed the visualization of the duodenal lumen, preventing the successful placement of lumen-apposing metal stents. Volume reduction of a duodenal polyp was performed through epinephrine injection to assist in the successful endoscopic ultrasound-guided gallbladder drainage. Subsequently, the patient underwent elective endoscopic mucosal resection to remove the giant duodenal polyp.
El gesto del mueble
Authors: Pantaleón Panaro Carlos 
Published: December 2023

Sin desconocer otras manifestaciones del diseño que tuvieron difusión internacional y alcanzaron diferentes niveles de reconocimiento, transformándose en verdaderos íconos, este artículo reflexiona, especialmente, sobre el tema del movimiento de los objetos de mobiliario.
Más allá del movimiento que pueda tener el objeto en sí, ya sea el que posibilita su traslado de un lugar a otro, o el interno, que le permite reducir o ampliar su tamaño —tales como el plegado, enrollado, giro, balance—, a los efectos de esta reflexión, interesan los casos cuyas formas sugieren movimiento. No se hará referencia, pues, al movimiento propio del objeto, que podrá tenerlo o no, sino al movimiento que evoca su forma, lo anticipa o lo mantiene en suspenso. Estaríamos hablando de un movimiento potencial, una situación del objeto que podría llegar a ocurrir, captado por nuestros sentidos −en particular por la visión— y nuestra imaginación.
Esta condición, planteada como premisa de la investigación, abre el campo de análisis a una serie de objetos en los que se detecta esta propiedad —movimiento potencial o sugerido— alcanzada a través de distintos recursos de diseño asociados por lo general al manejo de la forma.
Did Russia's Invasion of Ukraine Induce Herding Behavior in the Indian Stock Market?
Authors: KHAN Tabassum , NATCHIMUTHU Natchimuthu , TA Krishna 
Published: December 2023

This study empirically examines the herding behavior of the Indian stock market investors during the heightened geopolitical tensions between Russia and Ukraine in 2022.
An intensified Russia-Ukraine geopolitical event window was constructed, and the high-frequency trading data (intraday) of the Nifty index was analyzed using Multifractal Detrended Fluctuation Analysis (MFDFA) to compute the 5th-order Hurst exponent (Hq (5)) that detects herding behavior.
The study's empirical results revealed the presence of profound herding behavior during the intensified Russia-Ukraine geopolitical event window. The study contributes to the existing literature on herding behavior by examining the impact of a geopolitical event on the Indian stock market. Additionally, the study utilizes MFDFA to compute Hurst exponents, a relatively new approach to detecting herding behavior in financial markets.
The findings of this study may assist investors and policymakers in understanding the impact of geopolitical events on financial markets and the potential for herding behavior among investors during times of heightened uncertainty. The study's results demonstrate the interconnectedness of global events and financial markets, highlighting the need for policymakers to consider the potential social and economic consequences of geopolitical events.
Assessment of ALINEA method performance at different loop detector locations using field data and micro-simulation modeling via AIMSUN
Authors: Luaibi Wafaa Khudhair , Leong Lee Vien , Al-Jameel Hamid Athab 
Published: December 2023

Abstract
A ramp metering (RM) or ramp signal is an effective method for traffic management, especially at merging sections in urban expressways. This research aims to assess the Asservissement Linéaire d’Entrée Autoroutière (ALINEA) method performance at different loop detector locations using field data and micro-simulation modeling via advanced interactive microscopic simulator for urban and non-urban networks (AIMSUN). The operation of RM was executed using the ALINEA method. The field data were collected from two locations in Manchester in the UK for calibration and validation in AIMSUN. Occupancy values at different loop detector locations were evaluated. The results indicated that the current simulation model could represent reality to acceptable limits. Increasing the number of detector locations at the merging entrance will decrease the occupancy value. The results showed that the effect of loop detector location is a significant factor in determining the critical occupancy of the merging section. Also, the downstream location is more appropriate for determining the congestion or critical status. The AIMSUN software showed significant consistency in representing field data of merging sections. The minimum value of GEH (Geoffrey E. Havers) that equal to 0.5 has been used to statistically and graphically demonstrate this behavior.
Gamma-ray shielding analysis using the experimental measurements for copper(ii) sulfate-doped polyepoxide resins
Authors: Mahmoud K. A. , Binmujlli Mazen M. , Marashdeh M. W. , Aljaafreh Mamduh J. , Saleh Ahmad , Hanfi M. Y. 
Published: December 2023

Abstract
The present work aims to study the effect of the CuSO4 additive on the physical and radiation-shielding properties of polyepoxide resins. As a result, a series of four samples with the chemical composition xCuSO4 + (100 − x) (epoxy resin and hardener) was synthesized. The fabrication of samples was performed under atmospheric pressure and at room temperature. The density of the fabricated CuSO4-doped polyepoxides resin was measured experimentally using an MH-300A densimeter with an accuracy of 0.001 mg·cm−3. A narrow beam transmission method with an NaI (Tl) detector was used to evaluate and describe the effect of CuSO4 on the linear attenuation coefficient of the fabricated composites in the γ-ray energy interval, which ranged between 33 and 1,332 keV. The estimated results showed a high enhancement in the µ values that increased from 0.259 to 1.749 cm−1, raising the CuSO4 concentration from 0 to 40 wt% at a γ-photon energy of 33 keV. The enhancement in the µ values decreased with an increase in the γ-photon energy to 1,332 keV, whereas the µ values increased from 0.077 to 0.102 cm−1 with an increase in the CuSO4 concentration between 0 and 40 wt%, respectively. This showed that increased µ values positively affected the half-value thickness (Δ
0.5, cm), mean free path (λ, cm), lead equivalent thickness (Δ
eq, cm), and the transmission factor (%); all of the mentioned parameters suffer a considerable decrease with increasing CuSO4 concentration between 0 and 40 wt%.
Unexplained subfertility: active or conservative management?
Authors: Ahmad Siti Maisarah , Mat Jin Norazilah , Ahmad Mohd Faizal , Abdul Karim Abdul Kadir , Abu Muhammad Azrai 
Published: December 2023

Abstract

Objectives
Unexplained subfertility (UEI) describes a couple whose standard subfertility workout consider acceptable but unable to conceived.

Methods
This retrospective study was conducted in the Advanced Reproductive Centre, UKM Hospital, Kuala Lumpur, from January 2016 to December 2019. The data of 268 UEI couples were obtained from the clinical database. Women aged 21–45 years old was included and further divided into four groups according to the female partner’s age and subfertility duration: group A (age <35 years and subfertility <2 years), group B (age <35 years and subfertility >2 years), group C (age >35 years and subfertility <2 years), and group D (age >35 years and subfertility <2 years). All statistical analyses were performed using SPSS 22.0 for Windows.

Results
A total of 255 cases were included in this study. The mean age of the women was 32.9 ± 4.04 years, and the mean subfertility duration was 5.04 ± 2.9 years. A total of 51 (20 %) cases underwent timed sexual intercourse, 147 (57.6 %) cases had intrauterine insemination (IUI), whereas 57 (22.4 %) cases opted for in vitro fertilization (IVF). A total of 204 cases underwent active management (IUI/IVF), which showed a significant difference (p<0.05). Out of eight clinical pregnancies, half of them were from group B.

Conclusions
Active management in younger women with a shorter subfertility duration revealed a better pregnancy outcome. Otherwise, individualized treatment should be considered in selecting a suitable treatment plan.
Research on electric energy measurement system based on intelligent sensor data in artificial intelligence environment
Authors: Zhang Jieliang , Jiang Libin , Zhang Huanghui , Zhao Sikan , Yong Lin 
Published: December 2023

Abstract
Electric power resources are the core energy for a country’s economic development and growth. China is at the peak of electric energy consumption at this stage. Improving the accuracy and integrity of electric energy metering technology is of great significance for evaluating the use and consumption of resources in China. Under the background of artificial intelligence, this research analyzes and studies the integrated module, demand status, performance optimization, and coupling degree of the electric energy metering system (hereinafter referred to as EES) through the application of two different types of sensors. The results show that the application of intelligent sensors has a better integration effect with the system management of electric energy metering, which plays a very important role in promoting the sustainable development of automation and informatization of the EES.