bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGEMBANGAN USAHATANI GAMBIR MELALUI PRODUK TANIN
Authors: Nasrul Wedy , Satria Dedi , Arief Rudi Kurniawan , Arel Afdhil , Suwita Leli , Ernanda Revi , Ramadhan Fajri 
Published: November 2023

Usahatani gambir menjadi mata pencarian pokok petani di wilayah sentra gambir. Produksi gambir saat ini fokus pada produk gambir biasa (lumpang). Produk yang dihasilkan saat ini memiliki mutu yang buruk dan harga yang rendah. Sehingga perlu pengembangan produk gambir untuk mendapatkan harga yang lebih baik dan tambahan penghasilan. Pengembangan usaha gambir penting agar petani tidak tergantung pada satu produk dan pasar. Penelitan ini menggunakan metode kulitatif dan kuantitatif. Metode kualitatif untuk menjelaskan pengembangan usahatani gambir berbasis tanin. Metode kuantitatif untuk menganalisis kelayakan pengembangan usaha gambir. Hasil penelitian menunjukan produksi gambir dapat dikembangkan dengan alat-alat sederhana dengan biaya terjangkau. Tanin memiliki harga yang lebih mahal dibanding harga gambir biasa. Harga gambir biasa sekitar Rp. 80.000,-/kg sedangkan harga tanin mencapai Rp. 300.000,-/kg. Pengembangan agroindustri tanin layak untuk dikembangkan, dimana hasil analisis Revenue Cost Ratio (R/C) sebesar 1,6. Break Event Point (BEP) untuk katekin Rp. 118.787,-/Kg jadi sangat menguntungkan dilihat dari harga tanin saat ini.Kata Kunci : Gambir, Petani, Tanin
Políticas públicas dilemas e desafios do programa Minha Casa Minha Vida na região metropolitana de Natal
Authors: Oliveira Osmar Faustino de , Neto Manoel Raymundo de Carvalho , Neto José Geraldo Pimentel 
Published: November 2023

O desempenho da política habitacional em Natal é um campo importante para vários estudos, porque existe algumas especificidades, tais como: a expansão urbana sucedida da construção dos conjuntos que é expressiva. Então, O Programa Minha Casa Minha Vida vem exercendo um papel de ordem social de razoável importância em relação ao binômio emprego e renda e no tocante a redução do déficit habitacional do país. O presente estudo tem como objetivo trazer dados e uma discussão do PMCMV na Região Metropolitana de Natal, para isso foi necessária uma revisão bibliográfica de autores que trabalharam com a temática abordada. Com os resultados, foi possível identificar que o programa não atende toda a população e que não cobre o déficit habitacional, atende as faixas de renda 2 e 3. A faixa de renda 1 é excluída, e a política pública não vem eliminado o déficit habitacional.
From New Media to New Piety: The Construction of Muhammadiyah Digital Piety Ideas
Authors: Mualimin  , Tokhirov Shakhzod , Ramadhana Nada 
Published: November 2023

Muktamar is the highest consultative forum in Muhammadiyah, held every five years to discuss and formulate various decisions on responding to the ummah and nationality issues. At the 48th Muktamar in 2022 in Surakarta, Muhammadiyah discussed six strategic issues, one of which was digital piety. This is very interesting because apart from Muhammadiyah, no Islamic organization in Indonesia has officially made the issue of digital piety a strategic issue to be discussed at its Muktamar. Therefore this study aims to analyze the construction of the idea of digital piety by Muhammadiyah. This study is qualitative research with a literature study approach. The data was obtained by collecting print and digital literature related to the idea of digital piety by Muhammadiyah. The data obtained were then analyzed using the Miles and Huberman interactive qualitative analysis model. This analysis model has three stages: data reduction, presentation, and conclusion. Analysis of the data obtained leads to two findings in this study. First, digital piety is interpreted by Muhammadiyah as behaving and doing activities in the digital space accompanied by morality and ethics based on Islamic values. At this level, digital piety will lead to more civilized interactions and activities in the digital space. Second, three dimensions build the construction of Muhammadiyah’s digital piety ideas, namely the ideological dimension, the normative dimension, and the internalization dimension. The three dimensions are related to one another to create a civilized digital culture.
The sugar kelp Saccharina latissima II: Recent Advances in farming and applications
Authors: Sather Maren , Diehl Nora , Monteiro Cátia , Niedzwiedz Sarina , Burgunter-Delamare Bertille , Bischof Kai , Scheschonk Lydia , Forbord Silje , Huiru Li 
Published: November 2023

The sugar kelp Saccharina latissima has received intense scientific attention over the last decades. In recent years, interest in cultivation of the species has strongly increased in the North Atlantic Ocean and the Eastern Pacific Ocean, driven by the great potential of S. latissima to be utilised for various industrial applications, including food, feed, and biomaterials. Accordingly, current research has focused on improving farming methods and technology, environmental impacts, and site selection. In addition, many studies have investigated the varying chemical composition of S. latissima, extraction of commercially interesting components, and the use of the biomass and its derived components in various applications. This review provides acomprehensive overview of farming and applications of S. latissima from the last 15 years. Additional insights on other research topics, such as ecology, physiology, biochemical and molecular biology of S. latissima, are given in the first review, “The sugar kelp Saccharina latissima I: recent advances in a changing climate” (Diehl et al. 2023).
DETERMINATION OF VITAMIN C AND MINERAL CONTENT OF TWO LOCAL SPECIES OF Carica papaya (SAMBA AND HORTUS GOLD PAPAYA) AT VARIOUS STAGES OF RIPENING
Authors: Aroh A. O. , Omoniyi K. I. , Mohammed F. R. 
Published: November 2023

Papaya (Carica papaya Linn) is a popular fruit grown in the tropical and subtropical parts of the world, also known as "pawpaw". The fruit is consumed when ripe and also processed. The many benefits of papaya are owed due to the high content of Vitamin A, B and C, and minerals. This study aimed at determining the concentration of vitamin C in two species of the fruits as a function of the ripening periods, using the redox titration method indicated that the concentration of vitamin C decreased from 98 mg/kg to 70 mg/kg in Samba papaya and from 96 mg/kg to 68 mg/kg in the Hortus gold papaya with ripening period. Samba papaya is recommended for vitamin C enhancement at the early ripening stage. Calcium, magnesium and potassium concentrations determined using atomic absorption spectrophotometry decreased in concentration with storage day. Domestic and industry supply of vitamin C and essential minerals is key to health need to be obtained from fruits at the optimum stage.
ANALISIS KEAMANAN PENGELOLAAN WEB SIMPEL UPN “VETERAN” JAWA TIMUR MENGGUNAKAN ISO 27001:2013
Authors: Pulungan Lawaahizh Hanifah , Radithya Markarito Ariputra  , Ardilla Firosya  , Diajeng Putri Widiastuti  , Permatasari Reisa 
Published: November 2023

Pada era digital yang terus berkembang saat ini, keamanan informasi dan perlindungan data menjadi faktor kritis yang harus dipertimbangkan dalam pengelolaan laboratorium solusi. Keamanan informasi yang digunakan pada Web SIMPEL berupa ISO 27001:2013. Tujuan penelitian ini untuk mengidentifikasi dan melakukan pemahaman yang lebih baik terhadap risiko keamanan informasi yang ada, serta menyediakan rekomendasi untuk peningkatan sistem keamanan pada Web SIMPEL. Untuk mencapai tujuan penelitian ini, pengumpulan data dilakukan menggunakan metode kualitatif dengan melakukan wawancara kepada Kepala Ruangan Laboratorium Solusi Universitas Pembangunan Nasional “Veteran” Jawa Timur. Berdasarkan hasil analisis dengan menggunakan ISO 27001:2013, Web SIMPEL belum memenuhi standar keamanan sistem informasi ISO 27001:2013. Hal tersebut diperoleh dari beberapa domain yang belum sesuai standar ISO 27001:2013 dijabarkan pada tabel Gap Analysis yang menunjukkan bahwa masih belum adanya kebijakan dalam keamanan sistem informasi, autentikasi pengguna, hingga belum adanya prosedur yang jelas. Hasil analisis yang ada pada tabel Gap Analysis berupa rekomendasi untuk memenuhi domain yang belum sesuai standar. Dengan adanya rekomendasi tersebut, diharapkan dapat membantu pengembangan Web SIMPEL dalam mencapai standar ISO 27001:2013 khususnya dalam hal information security.
KESADARAN MAHASISWA DALAM MELINDUNGI PRIVASI DATA PADA BANK DIGITAL
Authors: Kuslaila Nur Racana , Siti Oktavia Eka Putri  , Nabila Athifah Zahra  , Siti Mukaromah  
Published: November 2023

Adanya bank digital tentu memudahkan masyarakat untuk melakukan transaksi dengan cepat. Berbagai bank digital juga semakin banyak bermunculan di Indonesia seperti neobank, bank jago, seabank, dan lain-lain. Meskipun telah diawasi oleh otoritas jasa keuangan, pengguna juga harus waspada terhadap kerentanan privasi keamanan data nya. Terlebih dengan adanya kasus pencurian data di beberapa bank digital membuat pengguna harus sadar tentang keamanan data. Oleh karena itu, dalam artikel ini dilakukan survei dan analisis kesadaran keamanan dan privasi data pada pengguna bank digital. Dengan menggunakan model information Security Awareness (ISA) artikel ini berfokus pada dimensi knowledge, attitude, dan behavior pengguna bank digital.Hasil akhir yang digunakan adalah hasil dari proses kesimpulan rata-rata dari tiga variabel yang menunjukkan bahwa 85.52% responden memiliki knowledge yang cukup baik terhadap perlindungan privasi data dan 83,32% attitude responden cukup baik dalam bertindak ketika menggunakan bank digital serta didampingi 90% behavior responden memiliki kebiasaan yang baik dalam menjaga privasi datanya. Dapat dikatakan bahwa pengguna bank digital terutama di kalangan mahasiswa memiliki kesadaran yang baik dan perlu diperhatikan agar privasi data lebih aman dan terjaga.
ANALISIS PENGUKURAN FAKTOR ADOPSI TEKNOLOGI E-COMMERCE PADA PELAKU UMKM MENGGUNAKAN FRAMEWORK TOE
Authors: Zahra Nabila Athifah , Putri Amalia , Kamilah Ismiazzah , Kuslaila Nur Racana 
Published: November 2023

Teknologi informasi dan komunikasi dapat digunakan untuk mendukung sistem penjualan online yakni E-Commerce. Salah satu e-commerce yang digemari masyarakat adalah Shopee. Dalam kurun waktu beberapa tahun jumlah pengguna Shopee di Indonesia mencapai angka 50 juta pengguna. Namun, berdasarkan data Asosiasi E-Commerce Indonesia, masih terdapat gap sebesar 20% pelaku UMKM yang belum terdigitalisasi. Berdasarkan fakta tersebut, penelitian ini bertujuan untuk mengetahui dan mengukur faktor adopsi teknologi e-commerce Shopee terhadap pelaku UMKM. Adapun metode yang digunakan sebagai acuan dalam pengukuran adopsi e-commerce yaitu menggunakan model ukur teknologi, organisasi, lingkungan, dan individu atau dikenal dengan model ukur TOE (Technology Organization Environment). Penelitian ini menggunakan teknik sampling dengan total responden sebesar 100 pelaku UMKM yang menggunakan shopee merchant di Surabaya. Setelah dilakukan pembersihan data, uji validitas, realibilitas, dan uji hipotesis dapat disimpulkan bahwa keempat variabel memiliki pengaruh positif terhadap adopsi e-commerce namun tidak signifikan karena nilai p-value didapatkan lebih besar dari 0.05. Nilai tidak signifikan bisa disebabkan karena masih terdapat variabel lain yang menjadi faktor determinan adopsi e-commerce. Hal ini diperkuat dengan hasil determinasi sebesar 0.340 yang menunjukkan bahwa variabel teknologi, organisasi, dan lingkungan dapat menjelaskan variabel dependen adopsi e-commerce sebesar 34% dan 66% sisa nya merupakan kontribusi dari faktor selain penelitian ini.
LITERASI DIGITAL PADA MASYARAKAT DESA
Authors: Pitrianti Siti , Sampetoding Eliyah A M , Purba Arini Anestesia , Pongtambing Yulita Sirinti 
Published: November 2023

Perserikatan Bangsa-Bangsa (PBB) menetapkan tujuan pembangunan berkelanjutan (SDGs) yang didukung melalui pembangunan pada desa secara masif dengan membentuk desa menjadi Desa Cerdas. Prinsip SDGs yang digunakan dalam pembangunan desa cerdas terdiri dari enam pilar utama yaitu Masyarakat, Ekonomi, Tata Kelola Pemerintahan, Lingkungan, Kehidupan, dan Mobilitas. Desa Cerdas menganut prinsip Masyarakat Cerdas yang berorientasi pada digital. Aspek yang perlu dikembangkan untuk membentuk masyarakat cerdas adalah literasi digital. Penelitian ini bertujuan untuk mengidentifikasi dan menentukan kategori literasi digital, dampak literasi digital, dan ciri literasi digital yang dibutuhkan masyarakat desa untuk membentuk Desa Cerdas. Penelitian ini juga diharapkan dapat mengidentifikasi peran literasi digital pada masyarakat desa. Penelitian ini dilakukan dengan pendekatan Systematic Literature Review. Hasil penelitian ini menemukan dua kriteria literasi digital, yaitu kemampuan sumber daya manusia dan tata kelola pelayanan terhadap masyarakat. Kategori kemampuan sumber daya manusia yang dibutuhkan adalah partisipasi SDM pada komunitas, keterbukaaan SDM dalam percepatan IT, dan peningkatan kemampuan sumber daya manusia. Sementara tata kelola pelayanan yang dibutuhkan adalah layanan publik, transparansi, dan kebijakan terkait literasi digital. Dampak dari literasi digital yang dirasakan masyarakat adalah peningkatan ekonomi masyarakat desa, adanya transparansi data, pencegahan cyber crime, informasi desa yang lengkap, pencegahan informasi hoax, peningkatan branding desa, integrasi data, layanan publik yang terintegrasi, kualitas pelayanan yang semakin baik, serta penyampaian aspirasi masyarakat desa semakin terbuka.
Faktor-Faktor Yang Mempengaruhi Kepatuhan Wajib Pajak Badan Pada Kantor Pajak Pratama Tanjung Karang
Authors: Anggraeni Yeni , Kusnadi Kusnadi , Sariningsih Eka 
Published: November 2023

Tax is a mandatory contribution to the state owed by every person or entity that is forced but still based on the Act. The minimum level of compliance of taxpayers causes, among others, taxpayers still perceive taxes as mandatory levies because they do not yet have a high awareness so that taxes are assessed as burdens. This study aims to provide relevant evidence of any of these ten factors, which affect taxpayer compliance in the Tanjung Karang Bandar Lampung KPP. This study uses primary data obtained from questionnaires. The population in this study are taxpayers who are active in the Bandar Lampung Primary Tax Office. The number of samples taken was 355 respondents. Analysis of the data used is multiple linear analysis. The results showed knowledge and environmental variables that had an effect on and significant on tax compliance, while other variables had no effect.Keywords : Attitude, Age, gender, knowledge, financial condition, environment, morals, sanctions, E-system and Socialization
Estimating cardiac output from coronary CT angiography: an individualized compartment model in comparison to the Stewart–Hamilton method
Authors: Leiknes Jon Bjarne , Hiorth Aksel , Havnen Jorunn , Greve Ole Jacob , Kurz Kathinka Dæhli , Larsen Alf Inge 
Published: November 2023

BackgroundAttenuation is correlated with the concentration of contrast medium (CM) in the arteries. The cardiac output (CO) affects the concentration of CM in the circulatory system; therefore, CO affects the time–density curve (TDC). Thus, estimating CO using TDC from test-bolus images acquired in computed tomography (CT) is possible. In this study, we compare two methods of estimating CO, namely, an individualized mathematical compartment model, integrating patient, contrast, and scanning factors with TDC, and the Stewart–Hamilton method based on the area under the curve of the TDC.Materials and methodsAttenuation in the aorta was measured during test-bolus in 40 consecutive patients with a clinical indication for coronary CT angiography (CCTA). Each participant underwent cardiac magnetic resonance imaging following CCTA to validate the estimated CO. The individual compartment model used TDC in conjunction with scanning and patient-specific parameters to estimate the concentration of CM and CO over time. This was compared to the CO calculated from the area under the curve using the Stewart–Hamilton method.ResultsBoth CO estimated with our individualized compartment model (r = 0.66, p &lt; 0.01) and the Stewart–Hamilton method (r = 0.53, p &lt; 0.01) were moderately correlated with CO measured with cardiac MRI. Body surface area (BSA) and time to peak (TTP) affected the accuracy of our model. Lower BSA resulted in overestimation, and lower TTP resulted in CO underestimation, respectively. We found no gender-specific difference in the accuracy of our model when correcting for BSA. The Stewart–Hamilton method performed better with a more complete TDC, whereas the compartment model performed better overall with a partial TDC.ConclusionThe TDC acquired in CCTA allows for CO estimation. Both the Stewart–Hamilton method and our mathematical compartment model show moderate correlation when applied to our data, although each method has its strengths and limitations. If the majority of the TDC is known, the Stewart–Hamilton method may be more reliable, but an individual compartment model is preferable when there are insufficient data points in the TDC. Regardless, both methods can potentially increase the diagnostic information acquired from a CCTA, which is increasingly recommended in clinical guidelines.
The role of WRKY transcription factors in exogenous potassium (K+) response to NaCl stress in Tamarix ramosissima
Authors: Chen Yahui , Zhang Xuanyi , Fan Yunlong , Sui Dezong , Jiang Jiang , Wang Lei 
Published: November 2023

Introduction: Soil salinization poses a significant challenge to plant growth and vitality. Plants like Tamarix ramosissima Ledeb (T. ramosissima), which are halophytes, are often integrated into planting schemes tailored for saline environments. Yet, the role of WRKY transcription factors in T. ramosissima, especially under sodium chloride (NaCl) stress mitigated by exogenous K+ application, is not well-understood. This research endeavors to bridge this knowledge gap.Methods: Using Pfam protein domain prediction and physicochemical property analysis, we delved into the WRKY genes in T. ramosissima roots that are implicated in counteracting NaCl stress when aided by exogenous K+ applications. By observing shifts in the expression levels of WRKY genes annotated to the KEGG pathway under NaCl stress at 0, 48, and 168 h, we aimed to identify potential key WRKY genes.Results: We found that the expression of 56 WRKY genes in T. ramosissima roots responded to exogenous K+ application during NaCl stress at the indicated time points. Particularly, the expression levels of these genes were primarily upregulated within 168 h. From these, 10 WRKY genes were found to be relevant in the KEGG pathways. Moreover, six genes, namely Unigene0024962, Unigene0024963, Unigene0010090, Unigene0007135, Unigene0070215, and Unigene0077293, were annotated to the Plant-pathogen interaction pathway or the MAPK signaling pathway in plants. These genes exhibited dynamic expression regulation at 48 h with the application of exogenous K+ under NaCl stress.Discussion: Our research highlights that WRKY transcription factors can modulate the activation or inhibition of related genes during NaCl stress with the application of exogenous K+. This regulation enhances the plant’s adaptability to saline environments and mitigates the damage induced by NaCl. These findings provide valuable gene resources for future salt-tolerant Tamarix breeding and expand our understanding of the molecular mechanisms of WRKY transcription factors in alleviating NaCl toxicity.
Molecular analysis of eight splicing variants in the hydroxymethylbilane synthase gene
Authors: Ren Yi , Wang Jiajia , Li Shuang , Lei Jiajia , Liu Yunfeng , Wang Yan , Gao Fei , Wang Jianhong , Yin Jianhong , Yang Jing 
Published: November 2023

Background: Molecular genetic testing is the most sensitive and specific method to confirm acute intermittent porphyria (AIP), a rare autosomal dominant disease, caused by Hydroxymethylbilane synthase (HMBS) gene mutation. According to the Human Gene Mutation Database (HGMD), approximately 20% of the reported HMBS gene variants affect pre-RNA splicing. Thus, the ensuing challenge is how to decipher the pathogenicity of these splicing variants.Methods: Using next-generation sequencing, we identified a novel heterozygous variant in the HMBS gene (c.160 + 5G&gt;C) from a Chinese family with AIP. And, previously, seven HMBS variants (c.33 + 5G&gt;A, c.88-16_88-4del, c.88-2A&gt;G, c.161-1G&gt;C, c.652-1G&gt;A, c.772-2A&gt;G and c.772-1G&gt;C) have been reported to be linked with AIP. Herein, we performed a valid and novel in vitro minigene assay to analyze the pathogenicity of these eight splicing variants.Results: By minigene assay in 293 T cell experiments, we demonstrated that all eight variants caused splicing defects in the pre-mRNA of the HMBS gene: c.160 + 5G&gt;C (intron3p_141bp retention), c.33 + 5G&gt;C(intron1p_91bp retention), c.88-16_88-4del and c.88-2A&gt;G (Exon3p_15bp deletion), c.161-1G&gt;C (Exon4p_18bp deletion), c.652-1G&gt;A (Exon11p_1bp deletion), c.772-2A&gt;G and c.772-1G&gt;C (intron11q_104bp retention or Exon12p_4bp deletion).Encouragingly, the c.160 + 5G&gt;C RNA sequencing from peripheral blood lymphocytes was consistent with the minigene assay result.Conclusion: We have made a pioneering attempt to apply minigene in vitro validation to the HMBS gene to evaluate the splicing effect of eight variants, including a novel splice variant (c.160 + 5G&gt;C). This study provides a molecular basis for future research on the pathogenesis and gene therapy of AIP.
A look at the past to draw lessons for the future: how the case of an urgent ICU transfer taught us to always be ready with a plan B
Authors: Brunelli Laura , Miotto Edoardo , Del Pin Massimo , Celotto Daniele , Moccia Adriana , Borghi Gianni , De Monte Amato , Macor Cristiana , Cocconi Roberto , Lattuada Luca , Brusaferro Silvio , Arnoldo Luca 
Published: November 2023

ObjectiveThe urgent transfer of an intensive care unit (ICU) is particularly challenging because it carries a high clinical and infectious risk and is a critical node in a hospital’s patient flow. In early 2017, exceptional rainfall damaged the roof of the tertiary hospital in Udine, necessitating the relocation of one of the three ICUs for six months. We decided to assess the impact of this transfer on quality of care and patient safety using a set of indicators, primarily considering the incidence of healthcare-associated infections (HAIs) and mortality rates.MethodsWe performed a retrospective, observational analysis of structural, process, and outcome indicators comparing the pre- and posttransfer phases. Specifically, we analyzed data between July 2016 and June 2017 for the transferred ICU and examined mortality and the incidence of HAI.ResultsDespite significant changes in structural and organizational aspects of the unit, no differences in mortality rates or cumulative incidence of HAIs were observed before/after transfer. We collected data for all 393 patients (133 women, 260 men) admitted to the ICU before (49.4%) and after transfer (50.6%). The mortality rate for 100 days in the ICU was 1.90 (34/1791) before and 2.88 (37/1258) after transfer (p = 0.063). The evaluation of the occurrence of at least one HAI included 304 patients (102 women and 202 men), as 89 of them were excluded due to a length of stay in the ICU of less than 48 h; again, there was no statistical difference between the two cumulative incidences (13.1% vs. 6.9%, p = 0.075).ConclusionIn the case studied, no adverse effects on patient outcomes were observed after urgent transfer of the injured ICU. The indicators used in this study may be an initial suggestion for further discussion.