bluuebunny/crossref_metadata_2025_split huggingface dataset:
Investigation on Photo‐Assisted Fenton‐like Mechanism of Single‐Atom Mn–N–Fe–N–Ni Charge Transfer Bridge Across Six‐Membered Cavity of Graphitic Carbon Nitride
Authors: Li Di , Li Hongmiao , Wen Qi , Gao Chunyan , Song Fang , Zhou Jun 
Published: January 2024

AbstractHerein, Mn, Fe, and Ni single atoms are designed to be embedded into the six‐membered cavity of the adjacent graphite phase carbon nitride layer, and the 2p orbitals of interlayer N atoms are hybridized with 3d orbitals of the Mn, Fe, and Ni single atom to form Mn–N–Fe–N–Ni charge transfer bridge throughout the six‐membered cavity of the graphite phase carbon nitride. The DFT calculations provide a clear explanation for how the p–d orbital hybridization of Mn–N–Fe–N–Ni atoms facilitate the creation of a charge‐transfer pathway. This pathway, which is located in the Mn–N–Fe–N–Ni charge‐transfer bridge, serve as the catalyst for the degradation of oxytetracycline hydrochloride through photocatalysis. The photoatalytic activity is much higher than the graphite phase carbon nitride. The effects of the Mn–N–Fe–N–Ni charge transfer bridge on the migration of photogenerated carriers, photocatalytic degradation performance, and degradation mechanism are discussed in detail. In order to improve the degradation efficiency of oxytetracycline hydrochloride, the Mn–N–Fe–N–Ni charge‐transfer bridge is utilized to activate peroxymonosulfate (PMS) under visible light exposure. The factors affecting the activation of PMS for oxytetracycline hydrochloride degradation are thoroughly investigated, and the degradation mechanism is also analyzed. This research contributes to a better comprehension of the photo‐assisted Fenton‐like effect of single‐atom photocatalysts.
Supramolecular Hydrogel with Ultra‐Rapid Cell‐Mediated Network Adaptation for Enhancing Cellular Metabolic Energetics and Tissue Regeneration
Authors: Li Zhuo , Yang Boguang , Yang Zhengmeng , Xie Xian , Guo Zhengnan , Zhao Jianyang , Wang Ruinan , Fu Hao , Zhao Pengchao , Zhao Xin , Chen Guosong , Li Gang , Wei Fuxin , Bian Liming 
Published: January 2024

AbstractCellular energetics plays an important role in tissue regeneration, and the enhanced metabolic activity of delivered stem cells can accelerate tissue repair and regeneration. However, conventional hydrogels with limited network cell adaptability restrict cell–cell interactions and cell metabolic activities. In this work, it is shown that a cell‐adaptable hydrogel with high network dynamics enhances the glucose uptake and fatty acid β‐oxidation of encapsulated human mesenchymal stem cells (hMSCs) compared with a hydrogel with low network dynamics. It is further shown that the hMSCs encapsulated in the high dynamic hydrogels exhibit increased tricarboxylic acid (TCA) cycle activity, oxidative phosphorylation (OXPHOS), and adenosine triphosphate (ATP) biosynthesis via an E‐cadherin‐ and AMP‐activated protein kinase (AMPK)‐dependent mechanism. The in vivo evaluation further showed that the delivery of MSCs by the dynamic hydrogel enhanced in situ bone regeneration in an animal model. It is believed that the findings provide critical insights into the impact of stem cell–biomaterial interactions on cellular metabolic energetics and the underlying mechanisms.
Semimetallic Bismuthene with Edge‐Rich Dangling Bonds: Broad‐Spectrum‐Driven and Edge‐Confined Electron Enhancement Boosting CO2 Hydrogenation Reduction
Authors: Wang Bin , Chen Hailong , Zhang Wei , Liu Heyuan , Zheng Zhaoke , Huang Fangcheng , Liu Jinyuan , Liu Gaopeng , Yan Xingwang , Weng Yu‐Xiang , Li Huaming , She Yuanbin , Chu Paul K. , Xia Jiexiang 
Published: January 2024

Broad‐spectrum‐driven high‐performance artificial photosynthesis is quite challenging. Herein, atomically ultrathin bismuthene with semimetallic properties is designed and demonstrated for broad‐spectrum (ultraviolet‐visible‐near infrared light) (UV–vis–NIR)‐driven photocatalytic CO2 hydrogenation. The trap states in the bandgap produced by edge dangling bonds prolong the lifetime of the photogenerated electrons from 90 ps in bulk Bi to 1650 ps in bismuthine, and excited‐state electrons are enriched at the edge of bismuthine. The edge dangling bonds of bismuthene as the active sites for adsorption/activation of CO2 increase the hybridization ability of the Bi 6p orbital and O 2p orbital to significantly reduce the catalytic reaction energy barrier and promote the formation of C─H bonds until the generation of CH4. Under λ ≥ 400 nm and λ ≥ 550 nm irradiation, the utilization ratios of photogenerated electron reduction CO2 hydrogenation to CO and CH4 for bismuthene are 58.24 and 300.50 times higher than those of bulk Bi, respectively. Moreover, bismuthene can extend the CO2 hydrogenation reaction to the near‐infrared region (λ ≥ 700 nm). This pioneering work employs the single semimetal element as an artificial photosynthetic catalyst to produce a broad spectral response.
Broadband and Tunable Microwave Absorption Properties from Large Magnetic Loss in Ni–Zn Ferrite
Authors: Ghosh Subrata , Sharma Shweta , Li Wenjie , Nozariasbmarz Amin , Raman Lavanya , Liu Na , Goyal Gagan K , Zhang Yu , Perini Steven E. , Lanagan Michael , Priya Shashank , Poudel Bed 
Published: January 2024

AbstractHighly effective electromagnetic (EM) wave absorber materials with strong reflection loss (RL) and a wide absorption bandwidth (EBW) in gigahertz (GHz) frequencies are crucial for advanced wireless applications and portable electronics. Traditional microwave absorbers lack magnetic loss and struggle with impedance matching, while ferrites are stable, exhibit excellent magnetic and dielectric losses, and offer better impedance matching. However, achieving the desired EBW in ferrites remains a challenge, necessitating further composition design. In this study, impedance matching is successfully enhanced and EBW in Ni–Zn ferrite is broadened by successive doping with Mn and Co , without incorporation of any polymer filler. It is found that Ni0.4Co0.1Zn0.5Fe1.9Mn0.1O4 material exhibits exceptional EM wave absorption, with a maximum RL of −48.7 dB. It also featured a significant EBW of 10.8 GHz, maintaining a 90% absorption rate (RL < −10 dB) for a thickness of 4.5 mm. These outstanding properties result from substantial magnetic losses and favorable impedance matching. These findings represent a significant step forward in the development of microwave absorber materials, addressing EM wave pollution concerns within GHz frequencies, including the frequency band used in popular 5G technology.
Window Grilles‐Inspired Detachable and Heatable AgNWs/PU Composite Films for Indoor Electromagnetic Interference Shielding
Authors: Hu Jun , Lyu Pei , Liu Yuemei , Ren Jie , Sun Xiangdong , Wei Peng , Liu Xin 
Published: January 2024

AbstractLong‐time indoor exposure to electromagnetic waves generated by electronic devices has posed a threat to the health of young life. The threat may intensify in low‐temperature environments due to low immunity. Prolific endeavors have focused on developing electromagnetic interference (EMI) shielding materials but failed to meet the visible, portable, and temperature‐controllable indoor‐use requirements. Herein, a detachable and heatable AgNWs/PU composite film is fabricated by facile spray coating and quick melting. The half‐inserted 3D network structure of AgNWs on PU ensures stable and high conductivity, thus endowing sufficient EMI shielding performance at 27 dB for indoor use. The high transparency (≥73.2%) and strong electrostatic force enable the detachable and portable use of the composite film. The resulting Joule heat at the voltage of 5 V endows a heatable property, which raises to 44.8 °C within 60 s. The AgNWs/PU composite film can self‐adhere in an indoor protective chamber, enabling visual monitoring and blocking electromagnetic radiation while keeping a comfortable inside temperature. The facile fabrication makes the self‐adhesive and multifunctional film possible in large‐scale production for practical application.
An Intelligent Glove System for Real‐Time Multiple Electrical Signal Acquisition and Display
Authors: Qiu Yulin , Dai Xingyi , Yang Jingkun , Liao Jiaying , Han Jiaxin , Wu Yinghui , Cao Yajun , Zhang Xuyang , Zhong Aihua , Ni He , Huang Long‐Biao 
Published: January 2024

AbstractRealizing multimodal tactile perception for robots is highly desirable for achieving more intelligent human–machine interaction. A real‐time intelligent glove system that can capture and monitor hand tactile information, including pressure, bending, and temperature is proposed. This system processes the collected data and visualizes the tactile information in a 2D image. The intelligent glove system integrates a palm‐shaped sensor unit, a multi‐channel data acquisition board, and a data analysis module. The glove consists of 34 flexible sensors, including 28 pressure sensors, five bending sensors, and one temperature sensor, which convert biological information into electrical signals. By enhancing the performance of the system, the intelligent glove achieves high sensitivity and good fault tolerance, allowing it to analyze the multimodal tactile information of the entire hand with fast responsivity. By analyzing the acquired multi‐channel electrical signals, the system can analyze object shapes and various gripping states. This work paves the way for wearable devices used in multimodal tactile perception and promotes the emergence of new modes of human–machine interaction.
Surface‐Engineered Methylammonium Lead Bromide Single Crystals: A Platform for Fluorescent Security Tags and Photodetector Applications
Authors: Mahato Somnath , Tamulewicz‐Szwajkowska Magdalena , Singh Sudarshan , Kowal Dominik , Bose Shaona , Serafińczuk Jarosław , Czyż Krzysztof , Jędrzejewski Roman , Birowosuto Muhammad Danang , Ray Samit Kumar , Abdelhady Ahmed L. 
Published: January 2024

AbstractSurface/interface engineering of methylammonium lead bromide (MAPbBr3) single crystals (SCs) is crucial for carrier generation/recombination, separation, and transportation, thereby enabling superior optoelectronics. Herein, a surface‐engineered crystallization technique is presented in which a thin polycrystalline MAPbBr3 layer is in situ grown on the surface of bulk mm‐sized MAPbBr3 SCs. The growth direction and the atomic distribution of both the polycrystalline surface layer and the single crystalline core have been analyzed by damage‐free atomic‐resolution transmission electron microscopy (TEM). The polycrystalline nature of the crystals gives rise to bright green emission under UV light. Scanning probe microscopy results show that the current at the emissive MAPbBr3 film/MAPbBr3 SC surface is five times higher than that at a non‐emissive surface when illuminated. Lateral photodetectors based on MAPbBr3 film/MAPbBr3 SCs can achieve excellent detectivities (≈1013 Jones) and high photoresponsivities (≈20 A W−1). Furthermore, a semiconductor‐based fluorescence quick response (FQR) code is patterned on the same bright green‐emitting surface of the MAPbBr3 film/MAPbBr3 SC using a picosecond laser pulse, with a scalability of 3 × 3 mm2. An FQR code integrated with a photodetector may serve as a potential double security tag in bank cards, passports, door security, etc.
Optimizing Emission Stability in Blue Perovskite Light‐Emitting Diodes via Oxygen‐Plasma Treatment of NixOy Hole Transport Layer
Authors: Yan Zhen‐Li , Huang Hong‐Yu , Benas Jean‐Sebastien , Yang Ching‐Wei , Su Chun‐Jen , Liang Fang‐Cheng , Chen Wei‐Cheng , Tsai Hsinhan , Jeng Ru‐Jong , Kuo Chi‐Ching 
Published: January 2024

AbstractCurrently, wide‐color gamut perovskite light‐emitting diodes (PeLEDs) are commonly controlled through halide composition tuning. However, the formation of perovskite crystals involving different ion radii of halogens often results in structural fragility and ionic defects, leading to emission instability during operation. This study showcases a novel approach to achieving a homogeneous and low‐defect crystalline state by regulating the thermodynamic nucleation mechanism of sky‐blue perovskite, thereby enhancing emission stability. Utilizing oxygen‐plasma treatment, a highly uniform surface energy is ensured for the nickel oxide acting as a hole transport layer. This treatment not only induces homogeneous nucleation of the perovskite layer but also effectively suppresses crystal defects. Simultaneously, the uniform surface energy alleviates halide phase separation caused by Ostwald ripening. Upon optimizing the fabrication conditions for sky‐blue perovskite, the resulting PeLEDs, featuring an electroluminescent peak at 486 nm, attain a luminance of 1125.3 cd m−2 with exceptional electroluminescent stability and a T50 lifetime. Furthermore, gaining insights into the thermodynamic nucleation mechanism in mix‐halides and perovskites contributes to the advancement of research on sky‐blue PeLEDs and offers valuable perspectives for future development.
Phosphine‐Free NNN‐Manganese(II) Catalyzed C‐alkylation of Methyl N‐Heteroarenes via Borrowing Hydrogen
Authors: Rong Qiang , Li Xiaojing , Sun Nan , Hu Baoxiang , Hu Xinquan , Jin Liqun 
Published: January 2024

AbstractMn(II)‐catalyzed alkylations of methyl N‐heteroarenes was reported via borrowing hydrogen strategy with alcohols as the alkylating reagent. The developed geometry‐constrained benzimidazole‐iminopyridyl ligand played a key role in promoting the transformation and stablizing the metal center. A wide range of alcohols (aromatic, heteroaromatic and aliphatic) and methyl N‐Heteroarenes could be able to apply in the current catalytic system, with TON up to 7400.
Swelling via Impedimetry Using Specifically Adhered Hydrogels on Co‐Planar Microfabricated Electrodes
Authors: Whitney Lauren V. , Abasi Sara , Aggas John R. , Guiseppi‐Elie Anthony 
Published: January 2024

AbstractResponsive hydrogels adhered to microfabricated electrodes find applicability as chemical or biological sensors and in electro‐stimulated drug delivery. A well‐defined method of cleaning, surface modification, and surface functionalization of microlithographically‐fabricated biochips composed of heterogeneous, abio surfaces (gold and glass) is presented for the reproducible adhesion of responsive hydrogels. The method uses cleaning approaches adapted from the semiconductor electronics industry and combines these with reactive organosilane chemistry to achieve the specific (covalent) attachment of UV cross‐linked, poly(HEMA‐co‐PEGMA‐co‐HMMA)‐based hydrogels. Specific attachment of hydrogels via acryloyl‐poly(ethylene glycol)‐3500 n‐hydroxysuccinimide (APNHS)‐functionalized surfaces and subsequent hydrogel hydration resulted in the strongest adhesive force as determined by centrifugal adhesion testing. Comparison with substrates functionalized via hydroxyl‐poly(ethylene glycol)‐3500 n‐hydroxysuccinimide (PNHS) confirmed the superiority of adhesion involving covalent bonding (APNHS) (4.48 kPa) versus hydrogen bonding (PNHS) (1.29 kPa). Adhered, fully hydrated and dehydrated hydrogels are characterized by Electrochemical Impedance Spectroscopy (EIS) and their hydration kinetics determined using impedimetry at a rationalized frequency. Impedimetry confirmed that p(HEMA‐co‐PEGMA‐co‐HMMA) hydrogels have an equilibration time of ≈30 min, a diffusion‐dependent rate coefficient k1 = 0.311 s−0.5 and relaxation‐dependent coefficient k2 = −0.022 s−1. Hydrogel swelling may be studied by impedimetry to fashion biomedical devices for co‐joined, real‐time biosensing with electro‐stimulated drug delivery.
Fine‐scale genetic structure in the orchidGymnadenia conopseais not associated with local density of flowering plants
Authors: Sletvold Nina , Joffard Nina , Söderquist Linus 
Published: January 2024

AbstractPremiseDensity‐dependent pollinator visitation can lead to density‐dependent mating patterns and within‐population genetic structure. InGymnadenia conopsea, individuals in low‐density patches receive more self pollen than individuals in high‐density patches, suggesting higher relatedness at low density. Ongoing fragmentation is also expected to cause more local matings, potentially leading to biparental inbreeding depression.MethodsTo evaluate whether relatedness decreases with local density, we analyzed 1315 SNP loci in 113 individuals within two large populations. We quantified within‐population genetic structure in one of the populations, recorded potential habitat barriers, and visualized gene flow using estimated effective migration surfaces (EEMS). We further estimated the magnitude of biparental inbreeding depression that would result from matings restricted to within 5 m.ResultsThere was no significant relationship between local density and relatedness in any population. We detected significant fine‐scale genetic structure consistent with isolation by distance, with positive kinship coefficients at distances below 10 m. Kinship coefficients were low, and predicted biparental inbreeding depression resulting from matings within the closest 5 m was a modest 1–3%. The EEMS suggested that rocks and bushes may act as barriers to gene flow within a population.ConclusionsThe results suggest that increased self‐pollen deposition in sparse patches does not necessarily cause higher selfing rates or that inbreeding depression results in low establishment success of inbred individuals. The modest relatedness suggests that biparental inbreeding depression is unlikely to be an immediate problem following fragmentation of large populations. The results further indicate that habitat structure may contribute to governing fine‐scale genetic structure inG. conopsea.
As prey and pollinators, insects increase reproduction and allow for outcrossing in the carnivorous plant Dionaea muscipula
Authors: Hamon Laura E. , Youngsteadt Elsa , Irwin Rebecca E. , Sorenson Clyde E. 
Published: January 2024

AbstractPremiseUnderstanding the factors that limit reproductive success is a key component of plant biology. Carnivorous plants rely on insects as both nutrient sources and pollinators, providing a unique system for studying the effects of both resource and pollen limitation on plant reproduction.MethodsWe conducted a field experiment using wild‐growing Dionaea muscipula J. Ellis (Droseraceae) in which we manipulated prey and pollen in a factorial design and measured flower production, number of fruits, and number of seeds. Because understanding reproduction requires knowledge of a plant species' reproductive and pollination biology, we also examined the pollination system, per‐visit pollinator effectiveness, and pollen‐ovule (P/O) ratio of D. muscipula.ResultsPlants that received supplemental prey produced more flowers than control plants. They also had a higher overall fitness estimate (number of flowers × fruit set (total fruits/total flowers) × seeds per fruit), although this benefit was significant only when prey supplementation occurred in the previous growing season. Neither pollen supplementation nor the interaction between pollen and prey supplementation significantly affected overall plant fitness.ConclusionsThis study reinforces the reliance of D. muscipula on adequate prey capture for flower, fruit, and seed production and a mobile pollen vector for reproduction, indicating the importance of considering insects as part of an effective conservation management plan for this species.
Neutrophils in sickle cell disease: Exploring their potential role as a therapeutic target
Authors: de Ligt Lydian A. , Gaartman Aafke E. , Biemond Bart J. , Fijnvandraat Karin , van Bruggen Robin , Nur Erfan 
Published: January 2024

AbstractSickle cell disease (SCD) is an inherited hemoglobinopathy characterized by chronic hemolytic anemia and recurrent microvascular occlusions, resulting in acute painful events and progressive organ damage. Although primarily a red blood cell disorder, the pathophysiology of SCD is increasingly characterized as a complex interplay between several different cell types and cellular processes. Evidence is accumulating that neutrophils are phenotypically different in SCD and have a significant contribution in the pathophysiology of the disease. In this review, we summarize the currently available evidence on the role of neutrophils in SCD pathophysiology, demonstrating that neutrophils in SCD have an activated phenotype and play an important role in vaso‐occlusion and inflammation in SCD. Activation of neutrophils in SCD is primarily driven by hemolysis and ischemia–reperfusion injury. The ameliorating effects of treatments, for example, hydroxyurea, might be partly mediated by decreasing neutrophil counts and reversing the pro‐inflammatory properties. Whether the novel anti‐sickling therapies, reducing hemolysis, have an anti‐inflammatory effect on neutrophils, remains to be elucidated.
Family‐based genetic analysis in schizophrenia by whole‐exome sequence to identify rare pathogenic variants
Authors: Shang Binli , Yang Runxu , Lian Kun , Dong Lei , Liu Hongbing , Wang Tianlan , Yang Guangya , Xi Kang , Xu Xiufeng , Cheng Yuqi 
Published: January 2024

AbstractSchizophrenia (SCZ) is influenced by a combination of genetic and environmental factors. Although several studies have been conducted to identify the causative loci and genes, few of these loci or genes can be repeated due to the high phenotypic and genetic heterogeneity of disease, and their mechanisms are not fully understood. There may be some “missing heritability” that has not yet been found. In order to investigate the deleterious heritable mutations, whole‐exome sequencing (WES) in pedigrees with SCZ was used in the current work. Two unrelated pedigrees with SCZ were recruited to perform WES. Genetic analysis was next performed to find potential variants in accordance with the prioritized strategy. Followed by genetic analysis to detect candidate variants according to the prioritized strategy. Next, a series of algorithms was used to predict the pathogenicity of variants. Sanger sequencing was finally conducted to verify the co‐segregation. Recessive mutations in six genes (TFEB, SNAI2, TFAP2B, PRKDC, ST18 in Pedigree 1 and PKHD1L1 in Pedigree 2) that co‐segregated with SCZ in two families were discovered through genetic analysis by WES. Sanger sequencing verified that all of the mutations in the affected siblings were homozygous. These results corroborated the hypothesis that SCZ exhibits strong heterogeneity and complex inheritance patterns. The newly discovered homozygous variations deepen our understanding of the mutation spectrum and offer more proof for the involvement of TFEB, SNAI2, TFAP2B, PRKDC, ST18, and PKHD1L1 in the development of SCZ.
A Semisynthesis Platform for the Efficient Production and Exploration of Didemnin‐Based Drugs
Authors: Zhang Haili , Li Xuyang , Hui Zhen , Huang Shipeng , Cai Mingwei , Shi Wenguang , Lin Yang , Shen Jie , Sui Minghao , Lai Qiliang , Shao Zongze , Dou Jie , Luo Xiaozhou , Ge Yun , Tang Xiaoyu 
Published: January 2024

AbstractPlitidepsin (or dehydrodidemnin B), an approved anticancer drug, belongs to the didemnin family of cyclic depsipeptides, which are found in limited quantities in marine tunicate extracts. Herein, we introduce a new approach that integrates microbial and chemical synthesis to generate plitidepsin and its analogues. We screened a Tistrella strain library to identify a potent didemnin B producer, and then introduced a second copy of the didemnin biosynthetic gene cluster into its genome, resulting in a didemnin B titer of approximately 75 mg/L. Next, we developed two straightforward chemical strategies to convert didemnin B into plitidepsin, one of which involved a one‐step synthetic route giving over 90 % overall yield. Furthermore, we synthesized 13 new didemnin derivatives and three didemnin probes, enabling research into structure–activity relationships and interactions between didemnin and proteins. Our study highlights the synergistic potential of biosynthesis and chemical synthesis in overcoming the challenge of producing complex natural products sustainably and at scale.