bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bibliometric analysis of the global research status and trends of mechanotransduction in cancer
Authors: Zhang Yi-Zhan , Li Meng-Zhu , Wang Guang-Xin , Wang Da-Wei 
Published: November 2023

BACKGROUND
The development of cancer is thought to involve the dynamic crosstalk between the tumor cells and the microenvironment they inhabit. Such crosstalk is thought to involve mechanotransduction, a process whereby the cells sense mechanical cues such as stiffness, and translate these into biochemical signals, which have an impact on the subsequent cellular activities. Bibliometric analysis is a statistical method that involves investigating different aspects (including authors’ names and affiliations, article keywords, journals and citations) of large volumes of literature. Despite an increase in mechanotransduction-related research in recent years, there are currently no bibliometric studies that describe the global status and trends of mechanotransduction-related research in the cancer field.
AIM
To investigate the global research status and trends of mechanotransduction in cancer from a bibliometric viewpoint.
METHODS
Literature on mechanotransduction in cancer published from January 1, 1900 to December 31, 2022 was retrieved from the Web of Science Core Collection. Excel and GraphPad software carried out the statistical analysis of the relevant author, journal, organization, and country information. The co-authorship, keyword co-occurrence, and keyword burst analysis were visualized with VOSviewer and CiteSpace.
RESULTS
Of 597 publications from 745 institutions in 45 countries were published in 268 journals with 35510 citation times. With 270 articles, the United States is a well-established global leader in this field, and the University of California system, the most productive (n = 36) and influential institution (n = 4705 citations), is the most highly active in collaborating with other organizations. Cancers was the most frequent publisher with the highest H-index. The most productive researcher was Valerie M. Weaver, with 10 publications. The combined analysis of concurrent and burst keywords revealed that the future research hotspots of mechanotransduction in cancer were related to the plasma membrane, autophagy, piezo1/2, heterogeneity, cancer diagnosis, and post-transcriptional modifications.
CONCLUSION
Mechanotransduction-related cancer research remains a hot topic. The United States is in the leading position of global research on mechano-oncology after almost 30 years of investigations. Research group cooperations exist but remain largely domestic, lacking cross-national communications. The next big topic in this field is to explore how the plasma membrane and its localized mechanosensor can transduce mechanical force through post-transcriptional modifications and thereby participate in cellular activity regulations and cancer development.
The Chinese Character as an Interface for Artistic Creation: Re-Cognition of Graphics and Phonetics
Authors: Gong Haomin 
Published: November 2023

ABSTRACT
This article examines two modern artistic explorations of the Chinese character. It takes Xu Bing’s Square Word Calligraphy and Jonathan Stalling’s Sinophonic English Poetry as examples and investigate how contemporary art reimagines and reconstructs the “potential” of Chinese characters and what ideological and political implications these processes may have for transcultural communication in today’s world. Situating the production of both works in Xu’s and Stalling’s respective creative experiences and larger sociocultural conditions, this article shows how both works, which deploy the graphics and the phonetics of the Chinese character as interfaces, engage in the politics of transcultural art creation and communication, and achieve their generative effects. Through this investigation, it hopes to illuminate the critical power of the Chinese character used as an interface in challenging linguistic, ideological, and cultural “norms” and questioning racial, national, and political prejudice.
Analysis of clinical characteristics and risk factors between elderly patients with severe and nonsevere Omicron variant infection
Authors: Liu Xiao-Qin , Lu Guan-Zhu , Yin Dong-Lin , Kang Yao-Yue , Zhou Yuan-Yuan , Wang Yu-Huan , Xu Jie 
Published: November 2023

BACKGROUND
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has led to millions of confirmed cases and deaths worldwide. Elderly patients are at high risk of developing and dying from COVID-19 due to advanced age, decreased immune function, intense inflammatory response, and comorbidities. Shanghai has experienced a wave of infection with Omicron, a new variant of SARS-CoV-2, since March 2022. There is a pressing need to identify clinical features and risk factors for disease progression among elderly patients with Omicron infection to provide solid evidence for clinical policy-makers, public health officials, researchers, and the general public.
AIM
To investigate clinical characteristic differences and risk factors between elderly patients with severe and nonsevere Omicron SARS-CoV-2 variant infection.
METHODS
A total of 328 elderly patients with COVID-19 admitted to the Ninth People’s Hospital Affiliated to Shanghai Jiao Tong University School of Medicine from April 2022 to June 2022 were enrolled and divided into a severe group (82 patients) and a nonsevere group (246 patients) according to the diagnosis and treatment protocol of COVID-19 (version 7). The clinical data and laboratory results of both groups were collected and compared. A chi-square test, t test, Mann-Whitney U test, hierarchical log-rank test, univariate and multivariate logistic regression, and hierarchical analyses were used to determine significant differences.
RESULTS
The severe group was older (84 vs 74 years, P < 0.001), included more males (57.3% vs 43.9%, P = 0.037), had a lower vaccination rate (P < 0.001), and had a higher proportion of comorbidities, including chronic respiratory disease (P = 0.001), cerebral infarction (P < 0.001), chronic kidney disease (P = 0.002), and neurodegenerative disease (P < 0.001), than the nonsevere group. In addition, severe disease patients had a higher inflammatory index (P < 0.001), greater need for symptomatic treatment (P < 0.001), longer hospital stay (P = 0.011), extended viral shedding time (P = 0.014), and higher mortality than nonsevere disease patients (P < 0.001). No difference was observed in the application of Paxlovid in the severe and nonsevere groups (P = 0.817). Oxygen saturation, cerebral infarction, and D-dimer were predictive factors for developing severe disease in patients with COVID-19, with D-dimer having an excellent role (area under the curve: 90.1%, 95%CI: 86.1-94.0%). In addition, D-dimer was a risk factor for developing severe COVID-19 according to multivariate stratified analysis.
CONCLUSION
The clinical course of severe COVID-19 is complex, with a higher need for symptomatic treatment. D-dimer is a suitable biomarker for identifying patients at risk for developing severe COVID-19.
Reflexões sobre a boa morte: em busca da autonomia perdida no processo de cuidado
Authors: Dias Quezia Cardoso , Mendonça André Luis de Oliveira , Magalhães Karla de Souza , De Mello Maycom Maia , Peres Patrícia Lima Pereira , Carvalho Eloá Carneiro 
Published: November 2023

O objetivo deste ensaio é refletir sobre a boa morte como uma proposta de direito à promoção e cuidado integral em saúde. Buscou-se analisar a temática da eu (boa), e thanatos (morte), sob a ótica de pensamento que terá como norte o cuidado em vez de a cura; a dimensão do sofrimento e não da dor, assim como a insuspeição de que o sujeito no fim de vida deve ter sua autonomia assegurada, sendo protagonista no processo decisório de sua morte. Ao se falar de boa morte refere-se à eutanásia, que será discutida à luz dos princípios da autonomia e da dignidade humana, buscando entender que tal prática se coaduna às diretrizes da integralidade do cuidado preconizada pela Constituição, por visar a qualidade de vida e o empoderamento do paciente; diferindo-a de outras práticas (como ortotanásia). Para tanto, optou-se por uma perspectiva ensaística, num estudo de reflexão, recorrendo a autores clássicos e contemporâneos a fim de fundamentar a presente pesquisa. Conclui-se que a eutanásia pode representar uma estratégia de respeito à dignidade humana e zelo pela emancipação subjetiva dos indivíduos.
The level of services and facilities in tourist sites for people with disabilities (accessible tourism) in Najran region
Authors: Alqarni Turki Mahdi , Hamadneh Burhan Mahmoud , Abduh Yahya Mohammed Bani 
Published: November 2023

Objectives: The purpose of this study was to determine the degree of services and facilities at tourist sites for individuals with disabilities (accessible tourism) in Najran region, as well as the disparities based on gender, type of disability, and nature of the visit.

Methods: Following the survey approach, the descriptive method was employed to fulfill the study's goal. The researchers' study technique (an electronic questionnaire) was employed. After validating its validity and dependability in the Saudi context, it was reduced to (14) elements. It was applied to a sample of (111) male and female volunteers with impairments (sight, hearing, and motor). A stratified random sample was drawn from Najran area of the Kingdom of Saudi Arabia.

Results: The results revealed that the level of services and facilities in tourist sites for individuals with disabilities (accessible tourism) was poor in Najran region. According to the answers of the study sample members, there are statistically significant differences in the level of services and facilities in tourist sites for people with disabilities (accessible tourism) in Najran region due to the type of disability variable in favor of visual disability and hearing disability. Furthermore, differences in the nature of the visit arose in favor of the nature of the visit with the center, although no statistically significant differences showed on the variable of gender. The study recommended that the authorities responsible for the tourism sector and tourism industry in the Kingdom of Saudi Arabia adopt an organized and thoughtful strategic plan. The plan must work to make the services and facilities of accessible tourism of high quality by following effective methods to stimulate the accessible tourism movement in a way that meets the Kingdom’s ambitions and vision 2030.
Emotional intelligence and management of school culture in Nigeria
Authors: Enefiok Ukpabio, Godfrey , Ekpenyong Ekanem, Ekpenyong , Iyaji Ngaji Mary , Eja Ojong, Felix , Nkemdilim Amalu, Melvina 
Published: November 2023

Purpose: The purpose of this study was to examine the concept of Emotional Intelligence (EI) and determine if managers’ emotional intelligence is a significant predictor of school culture. It also examined the possibility that gender may have an effect on managers' influence on school culture.
Design/Methodology/Approach: The study used a survey research method in order to learn more about how managers' emotional intelligence (EI) affected school culture in the study region during the time of the research. The independent t-test and multiple regression analysis were used to analyse the data using a sample of 100 vice principals.
Findings: The findings indicated that managers’ emotional intelligence influence on school culture varies by gender and that the emotional intelligence of school managers is a significant predictor of school culture.
Conclusion: According to the results' interpretation, emotionally intelligent principals can improve the school's environment making it more friendly and compassionate. Principal plays a significant role in their management effect on school culture.
Research Limitations and Practical Implications: Stakeholders can practically create a positive school culture and rid the school system of a toxic atmosphere by improving their employees’ EI competencies which are important comprehensible skills. Future research should aim at finding out specific areas of differences between male and female managers’ EI.
Contribution to the Literature: The results of this study may serve as a tool for policymakers in teacher and student personnel management, in addition to providing literature for future research. It may also serve as a resource for school improvement.
Evaluating the impact of computer accounting media applications on human development
Authors: Listiadi Agung , Rochmawati  
Published: November 2023

Purpose: Technology in education especially in accounting and computer learning is currently needed to support teacher performance and as a facility for students to participate in the learning process in the 21st century. This study aimed to determine whether there are differences in the performance of teachers before and after training on information technology-based learning evaluation models that use accounting applications.
Design/Methodology/Approach: The process of mastering Wondershare software is carried out for economics and accounting teachers in order to enhance the quality of learning. The research design uses a true pre-and post-tests experimental design with respondents being teachers in the field of accounting learning.
Findings: The results showed that there were differences before and after the training was carried out. After the training, the ability of teachers to perform the learning evaluation process improved.
Conclusion: Similarly, the responses of the teachers during the training and their perceptions of using the learning evaluation application were very enthusiastic.
Research Limitations and Implications: The limitation in this study is that there are many choices in using the questions in this application so not all the model questions in the application are taught.
Practical Implications: The findings of this study may be used to train instructors and raise their levels of proficiency, resulting in higher-quality human development.
Contribution to the Literature: The theoretical ramifications of this research include developing appropriate modelling in training and learning through the use of direct instructional applications.
Principio de especialidad en los consejos para la igualdad intergeneracional
Authors: Reyes Paladines Manolo Joselito , Añazco Aguilar Alan Osvaldo 
Published: November 2023

El presente trabajo de investigación tuvo como objetivo analizar la vulneración de derechos de las personas que pertenecen a los grupos de atención prioritaria particularmente a la niñez y adolescencia frente a la creación de los Consejos de Igualdad que cumplen funciones multicompetentes. La metodología utilizada tiene que ver con lo Dogmática: permitiendo investigar en el ordenamiento jurídico ecuatoriano sobre las los Consejos de Igualdad intergeneracional para saber con certeza, si los funcionarios cumplen con la garantía y de precautelar el cumplimiento y restitución de derechos de estos grupos de atención prioritaria, teniendo en cuenta que en este Consejo de Igualdad actualmente se incluyó a jóvenes mujeres y adultos mayores. Se concluyó que, no se está dando respuesta en restitución de derechos a los grupos de atención prioritaria debido a la falta de especialidad para atender a estos sectores vulnerables y a la falta de entidades de atención ejecutoras de las medidas de protección dictadas para restituir derechos vulnerados
NPK Fertilizer Test and Plant Population on The Growth And Years of Sorgum (Sorghum bicolor (L.) Moench)
Authors: Triyono Kharis , Priyono Priyono , Agustina Wahyu 
Published: November 2023

This study aims to determine the effect of NPK fertilizer dose and plant population on the growth and yield of Sorghum (Sorghum bicolor (L.) Moench).The design that was carried out was a Complete Randomized Block Design (RAKL) Factorial consisting of NPK fertilizer dose treatment with four levels and the second-factor Spacing with two levels, so there are eight treatment combinations repeated four times. The data obtained were analyzed by analysis of variance and to find out significant differences continued with Duncan's Multiple Range Test with a significant level of 5%. The results showed that the fertilizer dose treatment had a significant effect on plant height and seed weight per panicle, the plant population treatment had no significant effect on all observed parameters, and the combination of fertilizer dose and population treatments had no significant effect on all observed parameters. The treatment with a fertilizer dose of 300 kg/ha produced the highest seed weight per panicle of 91.79 gr, and the lowest fertilizer dose of 150 kg/ha produced a seed weight per panicle of 71.95 gr.
The Effect Of Cooperative Integrated Reading And Composition (Circ) Technique On Reading Comprehension Of Narrative Text At Grade Eighth Students Of SMP Swasta GKPS 3 Pematang Siantar
Authors: Kesia Rahelin Simanjuntak  , Dumaris E Silalahi  , Yanti Kristina Sinaga  
Published: November 2023

This research aimed to find Out The Effect Of Cooperative Integrated Reading And Composition (Circ) Technique On Reading Comprehension Of Narrative Text At Grade Eighth Students Of Smp Swasta Gkps 3 Pematang Siantar. This research design is quantitative. The quantitative method is a planned and careful problems solving method. In quantitative, systematically control data collection design, and will focus on constructing inductively concluded theories within the framework of empirically proving hypothesis. The quantitative research imposes objective measuring to collect numeric data that are utilized the answers of questions or test the specified hypothesis. Researcher will choose two groups as the sample, namely class VIII.1 and VIII.2. The two classes that researcher will choose as sample have studied the narrative text based on school education curriculum. By calculating the data, we can conclude that the t-test result (2.42) exceeded the t-table value at a significance level of 0.05 (2.00), meaning 2.42 > 2.00. This indicates that the use of the CIRC technique has a significant impact on students' reading comprehension. This is evident from the list of student scores in reading comprehension when using the CIRC technique compared to the conventional technique. In other words, grade eighth students' capacity at SMP Swasta GKPS 3 Pematang Siantar in reading comprehension is significantly impacted by using of CIRC technique.
Hubungan Antara Literasi Kesehatan Dengan Kualitas Hidup Siswa SMKN 9 Kota Tangerang
Authors: Anisatun Zahroh  , Eka Noviana Nasriyanto  , Cicirosnita J.Idu  
Published: November 2023

Berdasarkan arus informasi yang terus berkembang, literasi penting untuk memahami informasi. Budaya membaca buku yang rendah di Indonesia menjadi permasalahan yang berlangsung dalam jangka waktu yang lama. Indonesia berada di peringkat 62 dari 70 negara, menempatkannya sebagai salah satu dari 10 negara dengan tingkat literasi yang rendah. UNESCO juga mengungkapkan minat baca masyarakat Indonesia hanya sebesar 0,001 persen. Indonesia ditempatkan di peringkat 60 dari 61 negara dalam hal minat baca. Indonesia menempati urutan ke 40 dari 80 negara yang disurvei dalam hal kualitas hidup. Berdasarkan perbandingan internasional, Indonesia memiliki nilai rendah yaitu 1,8 dari skala 10. Tujuan penelitian ini untuk mengetahui hubungan antara literasi kesehatan dengan kualitas hidup siswa SMKN 9 Kota Tangerang. Metode pengambilan sampel dilakukan menggunakan metode kuantitatif dengan teknik Simple Random Sampling. Pengumpulan data dilakukan dengan pengisian kuesioner Health Literacy Survey (HLS-EU-SQ-10 IDN) dan World Health Organization Quality Of Life (WHOQOL-BREF) yang telah diadaptasi dan dibagikan ke 212 siswa, dengan metode statistik Chi Square. Hasil analisis hubungan antara literasi kesehatan dengan kualitas hidup diperoleh bahwa ada sebanyak 4 siswa (2,7%) yang bermasalah dengan literasi kesehatan tetapi kualitas hidupnya baik. Sedangkan siswa yang memiliki literasi kesehatan baik, sebanyak 143 siswa (97,2%), kualitas hidupnya juga baik. Berdasarkan uji Chi Square diperoleh nilai p = 0,014.
Joe Mitchell Chapple. Un viajero estadounidense en la España de Primo de Rivera.
Authors: Roldán Carreño Ángel 
Published: November 2023

This research paper tackles, from a historical perspective, the travelogue Vivid Spain (1926), written by the Bostonian Joe Mitchell Chapple as a result of his journey throughout Spain. The main aim of this work is to study in detail the vision of this North American traveller across the Peninsula. With this purpose, an analysis of the aforementioned work will be carried out taking into account its form and content, supported by the public opinion and the impact it generated in the American historical press of the time.
Este artículo aborda desde una perspectiva histórica el libro de viajes Vivid Spain (1926), escrito por el bostoniano Joe Mitchell Chapple como resultado de su periplo por España. El principal objetivo de este trabajo es profundizar en la visión que este viajero norteamericano obtuvo al recorrer la Península. Para ello, se efectúa un análisis de la referida obra en sus aspectos formales y de fondo, apoyado en la opinión pública y la repercusión que generó en la prensa histórica estadounidense de la época.
Pequeños reales de minas sureños en Nueva España:
Authors: Von Mentz Brígida 
Published: November 2023

This study focuses on three ancient and unknown mining centers in New Spain during the years 1570-1660. Situated in densely populated Indigenous regions, they did not develop into important towns, their silver production was intermittent, and they have received little attention of the mining historiography. Here, their particular characteristics are analyzed, compared among each other, and the proposal of this article is that they were not only settlements of unknown adventurers, but also mining centers of interest for investors belonging to the oligarchy. Moreover, during some decades, the mining enterprises had important effects on the surrounding Indigenous population that delivered the working force during years of deep demographic crisis.
En este trabajo se estudian para el periodo 1570-1660 tres antiguos reales de minas novohispanos poco conocidos, ubicados en zonas indígenas densamente pobladas. Como no devinieron en urbes de importancia y su producción de plata fue intermitente, no han recibido atención por parte de la historiografía minera. Se analizan sus características específicas, se comparan entre sí y se propone que fueron centros mineros trabajados no sólo por numerosos busca-fortunas desconocidos, sino también por grandes inversionistas pertenecientes a la oligarquía. Además, se observa cómo la presencia, durante algunas décadas, de empresas mineras en esas zonas indígenas repercutió sobre la población que proporcionó la fuerza de trabajo en una época de profunda crisis demográfica.