bluuebunny/crossref_metadata_2025_split huggingface dataset:
Graft-versus-host-disease in hematopoietic stem cell transplant recipients from diverse nationalities and transplant centers: a single-center cohort study in the UAE
Authors: Syed Naveed , Afrooz Imrana , Mir Farooq Ahmed , Khan Azmat Ali , Abdulla Nada J.M.H. , Hussain Shakir , Uttamchandani Ashok , Samer Hanin , Hassan Amera , Ghazali Gehad El , Hashmi Shahrukh 
Published: December 2023

Abstract
Background: Graft-versus-host-disease (GVHD), affecting 30-50% of cases, is a complex, multisystem disorder contributing to non-relapse mortality. In the UAE, where patients from different nationalities have historically sought transplants abroad at multiple transplant centers due to a lack of local facilities, the epidemiology of and outcomes for GVHD are unknown.
Objectives: To assess the incidence, risk factors and correlations of GVHD in different organs of HSCT recipients from different transplant centers and countries.
Methods: We conducted a single-center cohort study of 91 patients seen from January 2019 to December 2022. Data was extracted from Electronic Medical Records (EMRs). Descriptive statistics, bivariate correlation analyses, and relative risk calculations were utilized to present the results.
Results: 32% of the recipients were from different countries of origin that underwent transplants in transplant centers globally. The male-to-female ratio among recipients was 1.27; the average recipient age was 24 years. A total of 69.2% had matched identical donors, and gender distribution among donors was 61% male and 29.6% female. The most common indications for HSCT included acute leukemia (28.4%) and Beta-thalassemia (2 0.8%).
GVHD was observed in 43.9% of patients, with acute and chronic types almost equally present. Significant risk factors for GVHD included recipient age (p=0.004), HSCT indication (p=0.007), GVHD prophylaxis (p=0.03), pre-HSCT chemotherapy lines (p=0.03) and HLA match (p=0.66). The most affected organs were the skin (34%) and gastrointestinal tract (25.5%). Organ-specific GVHD correlated well with other organ GVHD, apart from lung and ocular GVHD. Risk factors aligned well with overall risk factors, except for lung GVHD. Ocular GVHD occurrence was less frequent compared to existing reports. Among the 10% deceased at study closure, 66% had GVHD.
Conclusions: Predominant HSCT recipients were young and mainly had related, HLA identical donors. Our study uniquely reported that HLA matching did not significantly influence GVHD outcomes. The skin emerged as the primary site for GVHD, ocular GVHD was less common than in other studies, and lung GVHD showed no association with typical risk factors or ocular GVHD. These variations contributed to the complexity and variability of GVHD risk and manifestations, which posed challenges for post-transplant care.Sample size and heterogeneity underscore the necessity for more extensive, multi-center research.
Jugendroman
Authors: Ullmann Anika 
Published: December 2023

[English title and abstract below]
Der Begriff Jugendroman wird gemeinhin als Sammelbegriff für eine Vielzahl von Genres verwendet. Bezeichnenderweise bleibt der Jugendroman selbst in den Definitionen abwesend, da er erst durch andere Gattungen als Ergänzung an Substanz gewinnt. Ziel des Aufsatzes ist es, eigenständige Erzähllogiken des Jugendromans zu benennen. Zu diesem Zweck wird zunächst ein Konzept von Jugendliteratur als Oberkategorie für mehrdimensionale Altersbilder skizziert und anschließend die Bedeutung von Jugend als sozialer Dimension des Alters aufgezeigt. Weiterhin wird eine Neugewichtung gängiger Erzähl- und Deutungsmuster vorgenommen, die intrapersonales Wachstum als Kern der Jugendliteratur etablieren und verfestigen. Daraus ergibt sich die Genese flexibler narratologischer Konzepte von Mobilität. Jugendromane sind demnach Narrative der äußeren, sozialen Mobilität, die die soziale Dimension des Alters konstruieren und verhandeln.

The Youth Novel Narratives of Social Mobility
The term ‘youth novel’ is commonly used as a collective term for a variety of genres. Significantly, the youth novel itself is rarely defined; it seems to gain substance only via other genres. The aim of this article is to outline the independent narrative logic of the youth novel. At the outset, a concept of youth literature as a superordinate category for multidimensional age emplotments is sketched, followed by a demonstration of the significance of youth as a social dimension of age. After that, the common narrative and interpretive patterns that establish and solidify intrapersonal growth as the core of young adult literature are rebalanced, and the genesis of a flexible, narratological concept of mobility emerges. Youth novels are thus shown to be narratives of external social mobility that construct and negotiate the social dimension of age.
St. Petersburg Academy of Arts and Sciences in the Network of European Academies in the Early Modern Period: The Place of "Arts" in the Structure of Scientific Knowledge
Authors: Келлер А.В. 
Published: December 2023

Анализируется структура научного знания Раннего Нового времени на примере места «художеств» в Академии художеств и наук, учрежденной именным указом из Сената 28 января (8 февраля) 1724 года в Санкт-Петербурге, и место последней в общеевропейской сети академических сообществ. Задача исследования показать актуальность и инновационность петровского академического проекта, как в силу специфических российских условий, так и в силу особенностей структуры научного знания Раннего нового времени. На примере 1) общего и различного между Петербургской академией наук и ведущими европейскими академиями, 2) особенностей словосочетания «художества и науки» в контексте петровского времени обосновывается тезис, что Художественные палаты и ремесленные мастерские при Академии не были всего лишь «обслуживающими» потребности науки и осуществлявшие «побочные» работы, не имеющие отношения к «чистой науке». Художества были самими инструментами «производства фактов» в науке и для науки, неотделимые от ее процесса. В момент учреждения Академии, без наук не могло быть художеств, как и художеств без наук. Присутствие словосочетания «художества и науки» в названии Академии хорошо объясняется семантикой слова «художество», включавшего в себя и науки, и искусства, и ремесла.
This article analyzes the structure of scientific knowledge in the Early Modern period with reference to the place of "arts" in the Academy of Arts and Sciences, established by a nominal decree from the Senate on January 28 (February 8), 1724 in St. Petersburg, and the place of the latter in the pan-European network of academic communities. The study aims to show the relevance and innovativeness of the Russian academic project, both due to specific Russian conditions and the peculiarities of the structure of scientific knowledge of the Early Modern period. Based on 1) the common and the different between the St. Petersburg Academy of Sciences and the leading European academies, 2) peculiarities of the phrase "arts and sciences" in the context of Petrine times, the thesis is substantiated that the Art Chambers and craft workshops at the Academy did not just "serve" the needs of science and carry out "side" work that had nothing to do with "pure science". The arts were themselves instruments of "fact production" in and for science, inseparable from its process. At the time of the establishment of the Academy, there could be no sciences without art, just as there could be no arts without sciences. The presence of the phrase "arts and sciences" in the name of the Academy is well explained by the semantics of the word "art", which included sciences, arts, and crafts.
What Was Said and What Jordan's «Getica» Kept Silent About
Authors: Буданова В.П. 
Published: December 2023

На основе системного анализа мировосприятия человека и писателя VI в. Иордана в статье предпринята попытка осмыслить сумбурное изложение событий, композиционные приемы путаницы, авторских сокрытий и исключений в тексте «Getica». Предложен анализ творческой стратегии Иордана в применении особых средств организации текста. Подчеркивается, что доминирующая тема сочинения сопровождалась тенденциозностью, композиционными приемами авторских умолчаний и исключений. Главное внимание в статье обращено на лакуны и громкие умолчания «Getica». Высказано предположение, что Иордан осуществлял их умышлено и достаточно грамотно. Ставится вопрос о необходимости актуализировать внимание к исследованию лакун и умолчаний письменного источника во избежание его двусмысленной интерпретации и фальсификации истории.
Based on a systematic analysis of the worldview of a person and a writer of the VI century . The article attempts to comprehend the chaotic presentation of events, compositional techniques of confusion, author's concealments and exceptions in the text of «Getica». The analysis of Jordan's creative strategy in the application of special means of text organization is proposed. It is emphasized that the dominant theme of the composition was accompanied by tendentiousness, compositional techniques of author's omissions and exceptions. The main attention in the article is paid to the lacunae and loud omissions of «Getica». It is suggested that Jordan carried them out intentionally and quite competently. The question is raised about the need to update attention to the study of lacunae and omissions of a written source in order to avoid its ambiguous interpretation and falsification of history.
Formation of the Temporal Regime of the Modern Era on the Example of the British Educational Board Games of the XVII-XVIII Centuries
Authors: Шпак Г.В. 
Published: December 2023

На протяжении раннего Нового времени в Англии изменяются темпоральные характеристики реальности. Представление об увядании мира и грядущем конце света заменяется доминированием идеи постепенного прогресса и движения к благоденствию и будущему процветанию. Концепция влияния планет и чисел на здоровье и жизнь людей также отходит на второй план. Традицию описаний, нацеленных на прогресс и приобретение новых знаний о мире, можно выявить в разных типах текстов – историях графств, утопических повествованиях и пр. В статье рассмотрены образовательные настольные игры, расцвет которых приходится в Англии на конец XVIII – первую половину XIX в. Символические числовые значения и восприятие движения по полю игры как духовного восхождения сменяется идеей соревнования, обучения и личностного прогресса. Географические образовательные игры знакомят с особенностями топографического устройства Британии и мира, вкладывая в его описание идеологические подтексты. Подобное мы можем увидеть как в исторических играх, так и в играх «в человеческую жизнь». На примере образовательных игр конца XVIII века показаны темпоральные характеристики, усваиваемые детьми и молодежью за счет иммерсивности игрового процесса, когда практически каждое явление, представленное в игре, требует от игрока определенного действия.
During the early modern period in England, the temporal characteristics of reality are being corrected. The idea of the gradual decline of the world and the coming end of the world is replaced by the dominance of the idea of gradual progress and movement towards future prosperity. The concept of the influence of planets and numbers on human health and life also faded into the background. The tradition of descriptions aimed at progress and the acquisition of new knowledge about the world can be identified in various types of sources - county histories, utopian narratives, etc. This article discusses a lesser-known type, which is educational board games, which flourished in England at the end of the 18th - first half of the 19th centuries. Symbolic numerical values and the perception of movement across the playing field as a spiritual ascent were replaced by the idea of competition, learning and personal progress. Geographic educational games introduced the features of the topographic structure of Britain and the world, putting ideological overtones into its description. We can see this both in historical games and in games “in human life”. Using the example of educational games of the late 18th century, the article shows the temporal characteristics acquired by children and youth due to the immersive nature of the game process, when almost every phenomenon presented in the game requires a certain action from the player.
Declassified Archival Documents about the Kharuzins Family
Authors: Керимова М.М. , Наумова О.Б. 
Published: December 2023

Харузины – три брата (Михаил, Николай, Алексей) и сестра Вера Николаевна – известные ученые-этнографы, стоявшие у истоков становления и развития этнографической науки в России. Их жизнь и научная деятельность подробно изучена одним из авторов статьи. Однако перипетии послереволюционной жизни семьи крупного политического и научного деятеля Алексея Николаевича Харузина (1864–1932) до сих пор были известны лишь в самых общих чертах. На основе данных Центрального архива ФСБ РФ, а также воспоминаний невестки А.Н. Харузина И.Е. Огневой, авторы восстанавливают самый трагический период жизни А.Н. Харузина, его жены Н.В. Харузиной, их сына Всеволода (конец 1920-х – 1930-е гг.).
The Kharuzins – three brothers (Mikhail, Nikolai, Alexei) and sister Vera Nikolaevna – are famous ethnographers who stood at the origins of the formation and development of ethnographic science in Russia at the end of the 19th – the first third of the 20th c. Their lives and scientific activities have been studied in detail by one of the authors of the article. However, the circumstances of the post-revolutionary life of the family of Aleksey Nikolaevich Kharuzin (1864–1932), the only brother who survived the revolution, currently are known only in the most general terms. Based on the data of the Central Archive of the FSB of the Russian Federation and the personal archive of E.P. Kryukova, containing the memoirs of the A.N. Kharuzin’s daughter-in-law I.E. Ogneva and some documents of his family members, the authors restore the most tragic period of A.N. Kharuzin’s life, as well as the lifes of his wife N.V. Kharuzina and their son Vsevolod (i.e. the end of the 1920s–1930s).
Politics of Memory in Eastern Europe the Transformation of Narratives in "Old" and "New" Media
Authors: Игаева К.В. 
Published: December 2023

Статья представляет собой рецензию на книгу «Исследование памяти и идентичность в России и Восточной Европе», вышедшую под редакцией Д. МакГлинн и Т. Джонс. В центре внимания находятся страны, в которых прошлое сильно политизировано, – Сербию, Украину, Польшу, Россию и страны Балтии. Распространяемые (прежде всего через медиа) в этих странах исторические нарративы предполагают ревизию представлений не только о прошлом, но и о будущем. Авторы предлагают рассматривать память как диалог с прошлым и с различными социальными группами, чьи версии исторической политики широко тиражируются современными медиа.
The article is a review of the book "Memory Research and Identity in Russia and Eastern Europe", edited by D. McGlynn and T. Jones. Its focus is on countries where the past is highly politicized, including historical narratives in Serbia, Ukraine, Poland, Russia, and the Baltic States, which involve a revision of ideas not only about the past, but also about the future in this region and beyond. The authors propose to consider memory as a dialogue with the past and with various social groups, whose versions of historical politics are widely replicated by contemporary media.
About One Page from the Subject Area "History of Ideas"
Authors: Задорожнюк И.Е. , Задорожнюк Э.Г. 
Published: December 2023

Авторы анализируют творческое наследие историка литературы Д.П. Святополк-Мирского. Оно трактуется как продолжение отечественной традиции, заложенной в трехтомных трудах по истории идей Иванова-Разумника, Г.В. Плеханова и Т.Г. Ма-сарика. Подчеркивается новаторский подход Д.П. Святополк-Мирского: привлечение к анализу истории идей инструментария психологии искусства, достижений представителей формальной школы и Общества изучения поэтического языка (ОПОЯЗ), зарождавшейся в то время философии науки.
The authors analyze the creative heritage of the literary historian D.P. Svyatopolk-Mirsky. It is interpreted as a continuation of the domestic tradition laid down in three-volume works on the history of the ideas of Ivanov-Razumnik, G.V. Plekhanov and T.G. Masaryk. His innovative approach is emphasized: attracting to the analysis of the history of the ideas of the toolkit of the psychology of art, the achievements of representatives of the formal school and the Society for the Study of the Poetic Language (OPOYAZ), the philosophy of science that was emerging at that time.
Early crop yield prediction for agricultural drought monitoring using drought indices, remote sensing, and machine learning techniques
Authors: Pandya Parthsarthi , Gontia Narendra Kumar 
Published: December 2023

Abstract

The unpredictability of crop yield due to severe weather events such as drought and extreme heat continues to be a key worry. The present study evaluated six meteorological and three Landsat satellite-based vegetation drought indices from 1986 to 2019 in the drought-prone-semi-arid Saurashtra region of Gujarat (India). Cotton and groundnut crop yield prediction models were developed using multiple linear regression (MLR), artificial neural network with MLP, and random forest (RF). The models performed crop yield estimation at two timescales, i.e., 75 days after sowing and 105 days after sowing. The standardized precipitation evapotranspiration index/reconnaissance drought index among meteorological drought indices, normalized difference vegetation anomaly index/vegetation condition index, and normalized difference water index anomaly were chosen as best highest correlations with crop yields. The RF-based models were found most efficient in predicting the cotton and groundnut yield of Saurashtra with R2 ranging from 0.77 to 0.92, Nash–Sutcliffe efficiency ranging from 71 to 90%, and root-mean-square error ranging from 80 to 133 kg/ha for cotton and 299 to 453 kg/ha for groundnut. This study demonstrated the method for making several decisions based on early crop yield prediction including timely drought mitigation measures.
Ecotoxicological and human health risk assessment of triclosan antibacterial agent from municipal wastewater treatment plants
Authors: Ebrahimi Afshin , Ebrahimpour Karim , Mohammadi Farzaneh , Moazeni Malihe 
Published: December 2023

Abstract

In this study, the occurrence and environmental risks related to triclosan (TCS) in the two wastewater treatment plants (WWTPs) were investigated in Isfahan, Iran. Influent and effluent samples were collected and analyzed by dispersive liquid–liquid microextraction (DLLME)–GC–MS method with derivatization. Moreover, the risk of TCS exposure was conducted for aquatic organisms (algae, crustaceans, and fishes) and humans (males and females). TCS mean concentrations in influent and effluent of WWTPs were in the range of 3.70–52.99 and 0.83–1.09 μg/L, respectively. There were also no differences in the quantity of TCS and physicochemical parameters among the two WWTPs. The mean risk quotient (RQ) for TCS was higher than 1 (in algae) with dilution factors (DFs) equal to 1 in WWTP1. Moreover, the RQ value was higher than 1 for humans based on the reference dose of MDH (RFDMDH) in WWTP1. Furthermore, TCS concentration in wastewater effluent was the influential factor in varying the risk of TCS exposure. The results of the present study showed the risk of TCS exposure from the discharge of effluent of WWTP1 was higher than WWTP2. Moreover, the results of this study may be suitable for promoting WWTP processes to completely remove micropollutants.
Removal of estrogens from primary settled sewage by repeated culture of Selenastrum capricornutum
Authors: Wang Ping , Luan Jianwen , Luo Lijuan 
Published: December 2023

Abstract

Biotransformation and biodegradation of estrogenic compounds by bacteria and even fungi have been reported widely, but the role of microalgae in the elimination of estrogens from municipal wastewater treatment plants and their interaction with other microorganisms in wastewater are not clear. This study reported the feasibility of repeatedly removing a mixture of 17β-estradiol (E2) and 17α-ethinylestradiol (EE2), each was 100 μg L−1, from primary settled municipal sewage by Selenastrum capricornutum (SC), a ubiquitous microalga, in four exposure cycles, each lasted 7 days, and how they interacted with the microbial consortium in sewage. Mixed estrogen in sewage stimulated the growth of SC, and the indigenous microorganisms in sewage also affected the microalgal growth. The indigenous microorganisms, particularly bacteria, could easily remove E2 (with 99.5% removal), so the role of SC was insignificant. On the contrary, EE2 was difficult to remove by indigenous microorganisms but the removal was significantly enhanced by SC, with almost all spiked EE2 being removed, even at the end of the fourth cycle (with 99.0% removal). These results indicated that SC, together with the indigenous microorganisms in wastewater, could be repeatedly used for simultaneous removal of E2 and EE2 from municipal sewage.
CMMRD-associated embryonic rhabdomyosarcoma in a child. Clinical case with literature review
Authors: Rodina A. D. , Polyakov V. G. , Krylov A. S. , Semenova V. V. , Kozlova V. M. , Nasedkina T. V. , Kashanina A. L. , Kozlov N. A. , Migunova V. V. , Gorbunova T. V. 
Published: December 2023

Introduction. Hereditary disorders in the DNA repair system can lead to the development of malignant neoplasms in childhood. DNA constitutional mismatch repair deficiency syndrome (CMMRD) is a very rare genetic autosomal recessive disorder caused by homozygous mutations in one of the four mismatch repair genes (MLH1, MSH2, MSH6, and PMS2). The frequency of occurrence is 0.0000001 of the adult and child population. For now about 150 observations have been published in the world literature. The prognosis for CMMRD syndrome is extremely unfavorable. The spectrum of tumors that make up the CMMRD syndrome is very wide, and includes mainly malignant brain tumors, tumors of the digestive tract, hematological malignancies, embryonic tumors, all of which develop in childhood.The purpose of the study is to report a case of CMMRD-associated embryonic rhabdomyosarcoma in a 3-year-old child.Conclusions. A review of the literature and the clinical case we have described show that rhabdomyosarcoma belongs to the tumor spectrum of the CMMRD syndrome. An immunohistochemical study revealed an isolated loss of PMS2 gene expression. Taking into account the clinical course of the CMMRD syndrome, a thorough study of the family history in patients with rhabdomyosarcoma is recommended, as well as a molecular genetic study, including the search for germinal mutations in genes in the DNA repair system and the assessment of microsatellite instability in the material of the tumor tissue. The clinical symptoms of CMMRD syndrome are nonspecific and depend on the morphological variant of the primary tumor. Distinctive molecular genetic features of this syndrome are: homozygous mutations with loss of function of the germline genes of the MMR system (mismatch repair) (MLH1, MSH2, MSH6 or PMS2).