bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sand control screen selection for cased dual‐annulus gas offshore wells based on scaled laboratory tests
Authors: Miri Rahman , Salimi Mahmoud , Stewart Suzanne , Bermudez Gonzalez Jose Manuel , Mazo Suárez Camilo , Nouri Alireza 
Published: December 2023

AbstractThis paper assessed and ranked several alternatives to control sand production in a well recompletion effort of offshore gas wells that have experienced massive sanding. The aim was to select an appropriate thru‐liner sand control system to increase well productivity. Four different screen types were evaluated, including a wire‐wrapped screen (WWS), slotted liner (SL), punched screen (PS), and a new multi‐layer open cell matrix polymer (OCMP) filter resembling gravel‐pack. The performance of screens regarding sand production and plugging was evaluated using a sand retention testing facility featuring a custom‐made device that mimics the unique well completion configuration. Further, a novel testing setup was constructed to assess the erosion potential of screens subject to high‐velocity gas and sand flow. All assessments were conducted under the representative actual well conditions. Laboratory tests indicate the superior performance of the OCMP filter compared to the other three options. Even though SL, WWS, and PS performed similarly in sanding, the WWS posed a higher erosion risk, with PS following in second place. The plugging tendency of the WWS was the least among all the options, whereas the PS had the highest tendency. Despite this, the WWS's sanding performance is expected to decline due to its vulnerability to erosion. Overall, the testing results indicated that the OCMP filter provides a promising solution to the issue of sand production in the gas wells being evaluated. However, the interaction of the OCMP filter with potential treatment chemicals in the wells should be tested before it can be used.
A Disulfide‐Based Poly(ether‐b‐amide) Copolymer with Rapid Self‐healing Ability under Moderate Conditions†
Authors: Lu Weijian , Zhu Ping , Zhao Ying , Wang Dujin , Dong Xia 
Published: December 2023

Comprehensive SummaryA disulfide‐based poly(ether‐b‐amide) copolymer with rapid self‐healing capability under moderate conditions was synthesized from 4,4’‐dithiodibutyric acid (DTDBA), isophorondiamine (IPDA) and poly(tetramethylene oxide) (PTMO) based on a two‐step method. The incorporation of IPDA with asymmetric structure and substantial steric hindrance not only effectively decreased the number of regular H‐bonds, but also inhibited the crystallization of polyamide segments, imparting the synthesized poly(ether‐b‐amide) copolymer with an amorphous structural feature. Based on the coordination of segmental diffusion and recombination of disulfide bonds and hydrogen bonds, the scratches and damaged mechanical properties of PEBADS‐I611 could be completely self‐healed after healing at 40 °C for only 11 min and 3 h, respectively.
A High‐Contrast Autolysosome Probe for Detecting Interaction between Autophagosomes and Autolysosomes in Mitophagy†
Authors: Wang Weihua , Han Chu , Xie Shengjie , Cong Zisong , Yang Zixuan , Feng Yuxin , Xiang Limin , Song Heng 
Published: December 2023

Comprehensive SummaryAutophagy is a multi‐step cell metabolism process in which cells remove damaged and unwanted materials. During autophagy, autophagosomes fuse with lysosomes to form autophagosomes. Autophagosomal membrane components are recycled from autolysosomes through the autophagosomal components recycling (ACR), while lysosomal components circulate on the autolysosomal surface through the autophagic lysosome reformation (ALR) process. Autolysosomes contain components from autophagosomes and lysosomes. However, whether there is a fusion between autolysosome and autophagosome or lysosome at the organelle level remains unknown. In this study, a pH and viscosity dual‐controlled mitochondria‐targeting fluorescent probe Mito‐Q was designed based on an asymmetric norcyanine to achieve the high‐contrast imaging of mitochondria‐containing autolysosomes. Mito‐Q not only effectively detected mitochondrial viscosity changes and mitophagy with high sensitivity, but more importantly, the fusion of mitochondria‐containing autolysosomes and autophagosomes (FMAA) was observed during autophagy by the real‐time confocal imaging of HeLa cells.
Cooperative and Bifunctional Adsorbent‐Catalyst Materials for In‐situ VOCs Capture‐Conversion
Authors: Mondal Sukanta K. , Aina Peter , Rownaghi Ali A. , Rezaei Fateme 
Published: December 2023

AbstractVolatile organic compounds (VOCs) are gases that are emitted into the air from products or processes and are major components of air pollution that significantly deteriorate air quality and seriously affect human health. Different types of metals, metal oxides, mixed‐metal oxides, polymers, activated carbons, zeolites, metal‐organic frameworks (MOFs) and mixed‐matrixed materials have been developed and used as adsorbent or catalyst for diversified VOCs detection, removal, and destruction. In this comprehensive review, we first discuss the general classification of VOCs removal materials and processes and outline the historical development of bifunctional and cooperative adsorbent‐catalyst materials for the removal of VOCs from air. Subsequently, particular attention is devoted to design of strategies for cooperative adsorbent‐catalyst materials, along with detailed discussions on the latest advances on these bifunctional materials, reaction mechanisms, long‐term stability, and regeneration for VOCs removal processes. Finally, challenges and future opportunities for the environmental implementation of these bifunctional materials are identified and outlined with the intent of providing insightful guidance on the design and fabrication of more efficient materials and systems for VOCs removal in the future.
Deep ultraviolet 266 nm laser excitation for flow cytometry
Authors: Telford William 
Published: December 2023

AbstractHigh dimensional flow cytometry relies on multiple laser sources to excite the wide variety of fluorochromes now available for immunophenotyping. Ultraviolet lasers (usually solid state 355 nm) are a critical part of this as they excite the BD Horizon™ Brilliant Ultraviolet (BUV) series of polymer fluorochromes. The BUV dyes have increased the number of simultaneous fluorochromes available for practical high‐dimensional analysis to greater than 40 for spectral cytometry. Immunologists are now seeking to increase this number, requiring both novel fluorochromes and additional laser wavelengths. A laser in the deep ultraviolet (DUV) range (from ca. 260 to 320 nm) has been proposed as an additional excitation source, driven by the on‐going development of additional polymer dyes with DUV excitation. DUV lasers emitting at 280 and 320 nm have been previously validated for flow cytometry but have encountered practical difficulties both in probe excitation behavior and in availability. In this article, we validate an even shorter DUV 266 nm laser source for flow cytometry. This DUV laser provided minimal excitation of the BUV dyes (a desirable characteristic for high‐dimensional analysis) while demonstrating excellent excitation of quantum nanoparticles (Qdots) serving as surrogate fluorochromes for as yet undeveloped DUV excited dyes. DUV 266 nm excitation may therefore be a viable candidate for expanding high‐dimensional flow cytometry into the DUV range and providing an additional incidental excitation wavelength for spectral cytometry. Excitation in a spectral region with strong absorption by nucleic acids and proteins (260–280 nm) did result in strong autofluorescence requiring care in fluorochrome selection. DUV excitation of endogenous molecules may nevertheless have additional utility for label‐free analysis applications.
Exploring the links among peripheral immunity, biomarkers, cognition, and neuroimaging in Alzheimer's disease
Authors: Li Jie‐Qiong , Zhang Ya‐Ru , Wang Hui‐Fu , Guo Yu , Shen Xue‐Ning , Li Meng‐Meng , Song Jing‐Hui , Tan Lan , Xie An‐Mu , Yu Jin‐Tai 
Published: December 2023

AbstractINTRODUCTIONWe analyzed relationships among peripheral immunity markers, cognition, Alzheimer's disease (AD)‐related biomarkers, and neuroimaging to understand peripheral immunity involvement in AD.METHODSPeripheral immunity markers were assessed in AD, non‐AD neurodegenerative disorders, and controls, examining their connections with cognition, AD‐related biomarkers, and neuroimaging using multiple regression models.RESULTSThe study included 1579 participants. Higher levels of white blood cell, neutrophil, monocyte, neutrophil‐to‐lymphocyte ratio (NLR), platelet‐to‐lymphocyte ratio (PLR), systemic immune‐inflammation index (SII), and lower lymphocyte‐to‐monocyte ratio (LMR) were associated with cognitive decline and more severe anxiety and depression. The impact of lower LMR, lymphocyte count, and higher NLR on cognitive decline is mediated through cerebrospinal fluid amyloid beta (Aβ) levels. Additionally, increased PLR, NLR, and SII were associated with brain atrophy and hippocampal Aβ deposition (amyloid positron emission tomography).DISCUSSIONPeripheral immunity markers offer a non‐invasive and cost‐effective means of studying AD‐related pathophysiological changes, providing valuable insights into its pathogenesis and treatment.Highlights
Peripheral immunity markers linked to cognitive decline and anxiety/depression.
Low LMR, LYM, and high NLR linked to reduced CSF Aβ, impacting cognition.
High PLR, NLR, SII associated with brain atrophy and hippocampal Aβ deposition
Ecomorphological convergence in the walking leg dactyli of two clades of ascidian‐ and mollusc‐associated shrimps (Decapoda: Caridea: Palaemonidae)
Authors: de Gier Werner , Helleman Pepijn , van den Oever Jurriaan , Fransen Charles H. J. M. 
Published: December 2023

AbstractSymbiotic species, living within or on the surface of host organisms, may evolve a wide range of adaptations as a result of various selection pressures, host specificity of the symbiont and the nature of the symbiosis. In tropical marine coral reef ecosystems, palaemonid shrimps (Crustacea: Decapoda: Caridea) live in association with at least five different invertebrate phyla. Host switches between (distantly) related host groups, and the thereby associated selection pressures were found to play a major role in the diversification of these shrimp lineages, giving rise to various host‐specific adaptations. Two lineages of palaemonid shrimp, which have switched from an ectosymbiotic association towards endosymbiosis, are studied for their morphological diversification and possible convergence. Special attention is given to the between‐phyla host switches involving ascidian and bivalve hosts, which are characteristic for these lineages. Using landmark‐based (phylo)morphospace analyses and Scanning Electron Microscopy, the walking leg dactylus shape and the microstructures on these dactyli are studied. No specific bivalve‐ or ascidian‐associated morphotypes were found, but morphological convergence in dactylus morphology was found in various species within the two studied clades with similar host groups. In addition, multiple lineages of bivalve‐associated species appear to be morphologically diverging more than their ascidian‐associated relatives, with ‘intermediate’ morphotypes found near host‐switching events.
Amazonian mixed‐species flocks demonstrate flexible preferences for vertical forest structure
Authors: Coddington Charles P. J. , Cooper W. Justin , Rutt Cameron L. , Mokross Karl , Amaral Bruna R. , Stouffer Philip C. , Luther David A. 
Published: December 2023

AbstractHow species interact with human‐disturbed environments is a central focus of conservation biology. Within disturbed landscapes, regenerating forests have potential to provide habitat for forest species, especially as increasing amounts of primary forest are lost. As secondary forest regenerates beside primary forest, it increases habitat heterogeneity. However, relatively little is known about the influence of habitat heterogeneity on space use. In this study, we analyzed the topography and vertical vegetation structure of regenerating forest, small forest fragments, and undisturbed rainforest in the central Amazon to determine (1) how these structural characteristics influence understory mixed‐species flock space use and (2) how the vegetative preferences of flocks varied across a disturbance gradient. We first used behavioral observations to quantify the vertical foraging niche of flocks and then associated variation in horizontal space use with the three‐dimensional features of forest structure. Surprisingly, we found that flock space use was not consistently associated with any variable, even though available habitat differed both within and across forest types. Overall, the best predictors were elevation and leaf area density within the subcanopy (16–25 m), yet most flock foraging occurred in the midstory (6–15 m). Together, these results indicate that while flocks may have certain habitat preferences, these preferences are flexible or idiosyncratic and do not correspond to a specific vertical profile. For example, flocks spent a disproportionate amount of time in low elevations when available, but not all flocks had access to low‐lying areas within their home ranges. Although other studies show flock size and diversity can be highly sensitive to habitat disturbance, mixed‐species flocks demonstrate remarkable plasticity as a unit, virtually saturating undisturbed and disturbed forest at our site, as long as regeneration has passed a certain threshold.
Two Synthesis Approaches of the 2H‐Tetrahydro‐4,6‐dioxo‐1,2‐oxazine Ring System of Alchivemycins A and B
Authors: Ishibashi Osamu , Meguro Yasuhiro , Kuwahara Shigefumi , Enomoto Masaru 
Published: December 2023

AbstractThe 2H‐tetrahydro‐4,6‐dioxo‐1,2‐oxazine (TDO) ring, a rare structural motif embedded in the molecular architecture of alchivemycins, is synthesized from 2,2,6‐trimethyl‐4H‐1,3‐dioxin‐4‐one via two routes. Both routes involve the intramolecular trapping of an acylketene intermediate by an internal hydroxy group to form the TDO ring as a key step. The first synthesis was achieved in 29 % overall yield from the starting material by a four‐step sequence featuring a DMAP−CaCl2‐mediated O‐ to C‐acyl migration reaction to install an acyl group at the C5 position of the TDO ring. The second synthesis was completed in 8 % overall yield from the same starting material as the first one through five steps by exploiting a photo‐induced double bromination reaction.
Does the absence or presence of sleep spindles on EEG have prognostic value for cognitive outcome in children with infantile epileptic spasms syndrome? A systematic literature review
Authors: Lähdetie Jaana , Muñoz‐Ruiz Miguel , Kokki Hannu 
Published: December 2023

AbstractInfantile Epileptic Spasms Syndrome (IESS) is an epileptic encephalopathy in childhood that affects infants under the age of two years. When spasm series occur, prognosis for cognitive outcome is poor in the majority of cases. The encephalopathy in IESS includes delayed maturation of normal sleep phenomena in the EEG, such as sleep spindles. Children with intellectual disabilities often have abnormal sleep, and children with sleep problems have difficulties learning at school. We examined whether there is evidence of prognostic value of detection of sleep spindles in the EEG of children with IESS on their future cognitive development. A systematic literature search yielded five studies touching this question. They were evaluated by two scorers independently. The lack of normal sleep patterns including lack of sleep spindles was used as a biomarker of poor cognitive outcome. Positive (PPV) and Negative (NPV) prognostic values were calculated. A summary of all five studies indicates a PPV of 82% and an NPV of 45%. Given the small amount of data, the retrospective quality of most studies, and the differences in the outcome parameters reported, it is prudent to say that currently available data do not allow us to conclude whether spindles have a specific and independent role in the cognitive prognosis of affected children. Since sleep spindles are needed for memory consolidation and demonstrate the active role of sleep for learning and memory, the hypothesis remains that their absence in the EEG may indicate an increased risk of cognitive delay, but more supporting data are needed to reach such a firm conclusion.
Numerical and experimental investigation of an Archimedes screw turbine for open channel water flow application
Authors: Abbas Zeshan , Waqas Muhammad , Khan Saad Saleem , Khatoon Rabia , Larkin Stephen , Zhao Lun 
Published: December 2023

AbstractLow‐head turbines are becoming an agricultural imperative due to their high efficiency, low cost, ability to operate at low flow rates and minimal environmental impact. Therefore, the Archimedes screw turbine (AST) can play a leading role for producing electric power, especially in Pakistan's rural areas where most of the places have less than 1 m head. In this research work, performance evaluation of AST was carried out at different flow velocities in terms of power coefficient and torque generated. Design parameters such as blade width, blade pitches, and blade rotational angles are also used for performance evaluation. For this purpose, computational fluid dynamic (CFD) analyses of AST blades were conducted at different water flow velocities (e.g., 1, 1.5, 2, 2.5, 3, and 3.5 m/s). ANSYS FLUENT was used for AST blade simulations using three different design parameters such as blade width, blade pitch, and blade rotational angles. Additionally, CFD simulations have inherent errors and uncertainties that may lead to findings and deviations from their exact or real values. To prevent these uncertainties and errors, an experimental study was also conducted to provide validation for the CFD simulation results. The results revealed from CFD simulations for optimized design parameters were then compared with experimental data. From the results, it was examined that the numerical findings were in good agreement with the experiment data. The highest power coefficient and power output values were obtained under optimized design parameters such as inner and outer diameter, blade pitch, blade width, blade rotation angles and shaft length (e.g., 40 mm, 120 mm, 130 mm, 2 mm, 60°, and 850 mm respectively). The findings can be useful to implement the AST unit for those places where the available water head is ranging from 1 to 6.5 m and a flow rate of 0.2–6.5 m3/s, especially for rural areas of Pakistan.
Terrestrial Isopods Generate Microplastics from Low-Density Polyethylene Without Effects on Survival
Authors: Musgrave C. , Prosser Ryan S. 
Published: December 2023

Abstract
With concern growing regarding the impact of microplastics (MPs) on terrestrial ecosystems, it is important to assess the role invertebrates may play in the fate of MPs within these ecosystems. Commonly, MPs enter these environments through improperly discarded waste or the application of treated biosolids and/or wastewater on agricultural soils. The present study investigated whether three species of terrestrial isopod (Porcellio scaber, Porcellio laevis, and Porcellionides pruinosus) ingest plastic debris and generate MPs during exposures varying from 24 h to 14 days and whether this may have an adverse effect on their health. Test vessels were designed to expose isopods to plastic fragments in the form of polyethylene plastic foam. Isopods were exposed to plastic that was either (1) pristine, or (2) weathered in a soil and water solution prior to incorporation in test vessels. When exposed to weathered polyethylene, all three species generated MPs (minimum–maximum size values for all durations inclusive: P. laevis = 114–1673 µm, P. scaber = 99–1635 µm, P. pruinosus = 85–1113 µm) through the consumption of macroplastic fragments with no observed impact on their health. In the shorter-duration exposures, the number of MPs generated by the isopod species in the present study was highly variable between experimental vessels (minimum–maximum generated MPs for 14-day exposure: P. laevis = 25–420, P. scaber = 50–583, P. pruinosus = 48–311). However, as the exposure durations increased, there was a clear trend of increasing MP generation, indicating that the isopods continued to consume the plastic fragments as long as the surface was weathered. A significant difference in the size of generated MPs was observed as well, with smaller isopod species generating smaller MP fragments on average. The results of the present study confirm that certain species of isopod can contribute to the generation of MPs, which constitutes an additional pathway of MP exposure to soil ecosystems. Environ Toxicol Chem 2024;43:784–792. © 2023 The Authors. Environmental Toxicology and Chemistry published by Wiley Periodicals LLC on behalf of SETAC.
The sensory evaluation and antimicrobial efficacy of Lactobacillus acidophilus supernatant on Salmonella enteritidis in milk
Authors: Kamali Abbas , Hosseini Hedayat , Mahmoudi Razzagh , Pakbin Babak , Gheibi Nematollah , Mortazavian Amir Mohammad , Shojaei Saeideh 
Published: December 2023

AbstractPostbiotics are metabolites derived from living probiotic bacteria like Lactobacillus strains, during the fermentation process and/or produced in pure form on laboratory scales. These compounds, depending on the type of probiotic from which they are prepared, have specific antibacterial agents such as: organic acids, bacteriocins, short‐chain fatty acids, and peptides. The objective of this study was to investigate the effect of Lactobacillus acidophilus supernatant (LAS) on the growth pattern of Salmonella enteritidis at fluctuating temperatures and the sensory evaluation of milk that contains this probiotic. Baranyi and Roberts's model determined the best‐fit curve for the microbial growth. According to mathematical equations, the highest and lowest specific growth (μmax) rates of S. enteritidis were obtained at 0.055 h−1 and 0.0059 h−1 and also highest and lowest maximum generation time (MGT) values were obtained at 20.06 h and 8.85 h, respectively. Sensory evaluation by the Triangel test reveals that LAS could not establish a significant (p > .05) adverse effect on milk perceptible. Regarding the results obtained in the present study, LAS, without causing adverse sensory change, could act as a safe food additive for the control of bacterial pathogens and reducing food waste, particularly in milk and milk‐containing food products.
The art of specimen orientation: Two‐dimensional maps for oropharynx squamous cell carcinoma
Authors: Divakar Prashanthi , Kim Stephanie S. , Kerr Darcy A. , Pettus Jason R. , Paydarfar Joseph A. 
Published: December 2023

AbstractThe goal of surgical treatment for oropharynx squamous cell carcinoma (SCCa) is resection to negative margins. Current methods of orienting resection specimens often do not give a comprehensive view, especially in oropharynx SCCa where specimens can lack anatomic landmarks. We created standardized two‐dimensional maps of oropharynx anatomy drawn to scale to improve communication between surgeons and pathologists. Notes regarding surgery including anatomic landmarks, areas of concern, additional margins, and relevant clinical information were added to the map. The maps guided pathology work‐up, and the pathologist could communicate details back to the surgeon on how the specimen was sectioned or locations of microscopic foci to direct future treatment and clinical monitoring. The use of two‐dimensional maps for oropharynx SCCa specimens offers a standardized solution to address the challenges of anatomic orientation. These maps summarized key pathological information, preserved clinical details from the specimens, and guided multidisciplinary conferences when planning adjuvant treatment.