bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meningkatkan Aktivitas, Kemampuan Literasi Sains dan Hasil Belajar Muatan IPA Menggunakan Model Plant and Teach
Authors: MA'RUF ANANG , Rafianti Wahdah Refia 
Published: November 2023

Abstract: The problem in this study is the low activity, scintific literacy skill and student learning outcomes in science content material Changes in The Form Of Objects in class V SDN 1 Sumber Alaska. The causes of these problems are that learning is still one-way, less interesting and meaningful, students are passive when learning, are not used to problem-solving activities and are scientifically literate. This type of research is Classroom Action Research (CAR) with a qualitative and quantitative approach which is carried out in four meeting and aims to describe teacher activities, analyze activities, scientific literacy abilities and student learningoutcomes. The result showed an increase, namely teacher activity obtained the proportion of 62.50% to 93.75% in the “very good” category, student activity obtained the proportion from 45% to 90% in the “almost entirely active” category, scientific literacy test result obtained the proportion from 50% to 78% eith the “high” category and learning outcomes get the proportion from 35% to 85%. So it can be concluded that the applications of the Plant and Teach model can increase activity, scientific literacy skills and student learning outcomes.
Abstrak: Permasalahan pada penelitian ini yaitu rendahnya aktivitas, kemampuan literasi sains dan hasil belajar siswa muatan IPA materi Perubahan Wujud Benda pada kelas V SDN 1 Sumber Alaska. Penyebab dari masalah tersebut adalah pembelajaran masih bersifat satu arah, kurang menarik dan bermakna, siswa pasif saat pembelajaran, tidak terbiasa dengan aktivitas pemecahan masalah dan berliterasi sains. Jenis penelitian ini adalah Penelitian Tindakan Kelas berpendekatan kualitatif dan kuantitatif yang dilaksankaan empat kali pertemuan dan bertujuan untuk mendeskripsikan aktivitas guru, menganalisis aktivitas, kemampuan literasi sains dan hasil belajar siswa. Hasil penelitian menunjukkan adanya peningkatan yaitu aktivitas guru memperoleh persentase dari 62.50% menjadi 93.75% dengan kategori “sangat baik”, aktivitas siswa memperoleh persentase dari 45% menjadi 90% dengan kategori “hampir seluruhnya aktif”, hasil tes literasi sains memperoleh persentase dari 50% menjadi 78% dengan katehori “tinggi” dan hasil belajar memperoleh persentase dari 35% menjadi 85%. Jadi dapat disimpulkan bahwa penerapan model Plant and Teach dapat meningkatkan aktivitas, kemampuan literasi sains dan hasil belajar siswa.
Pelanggaran Hak Cipta Pada Penjualan Buku Hasil Bajakan Berdasarkan Undang-Undang Nomor 28 Tahun 2014 Tentang Hak Cipta
Authors: Rejeki Henlia Peristiwi , Iriyanti Iriyanti , Dadang Dadang 
Published: November 2023

Menjual buku yang diproduksi secara ilegal merupakan kegiatan ilegal dan melanggar Undang-Undang Hak Cipta No. 28 Tahun 2014. Undang-undang memberikan sanksi yang jelas bagi mereka yang melanggar hukum. Permasalahan dari karya ini adalah bagaimana sanksi yang diberikan terhadap pelanggaran pengusaha yang berjualan secara illegal berdasarkan ketentuan Undang-Undang Hak Cipta 2014 28 dan bagaimana pengawasan pemerintah dan aparaturnya dalam penertiban peredaran penjualan barang bajakan. Buku. Dalam penelitian ini, menerapkan pendekatan empiris kanan dengan keterlibatan peneliti dalam kegiatan lapangan untuk memperoleh pemahaman tentang pelaksanaan UU Hak Cipta No. 28 Tahun 2014. Metode penelitian yang digunakan adalah pendekatan empiris kanan, yang melibatkan peneliti secara langsung di lapangan untuk mengamati implementasi UU Hak Cipta No. 28 Tahun 2014. Penelitian ini dilakukan berdasarkan situasi nyata di masyarakat guna memperoleh pemahaman yang lebih mendalam.. Tujuannya untuk mengetahui dan menemukan fakta dan informasi yang dibutuhkan. Kemudian mengumpulkan informasi yang diperlukan yang mengarah pada identifikasi masalah dan akhirnya penyelesaian masalah. Penelitian ini didukung oleh berbagai sumber data primer dan sekunder berupa wawancara, angket, observasi dan penelitian kepustakaan mengenai hal tersebut, antara lain UU Hak Cipta No. Setelah informasi diolah dan dirasa cukup, maka akan disajikan dalam bentuk naratif. Ketika data telah dikumpulkan dan diproses sepenuhnya melalui laporan atau tabel, analisis kualitatif dilakukan. Analisis data kualitatif adalah metode yang digunakan untuk menerangkan dan memaknai data yang terhimpun guna memperoleh pemahaman mengenai realitas yang ada.
Strategi Guru Dalam Menghadapi Character Loss Pada Pembelajaran Online Bagi Siswa Kelas 1 Sekolah Dasar
Authors: Fauzia Wulan 
Published: November 2023

Abstrak. Lamanya jangka waktu belajar daring di rumah yang disebabkan oleh pamdemi virus corona menyebabkan kekhawatiran adanya learning loss atau berkurangnya pengetahuan dan juga keterampilan belajar anak (Andriani, dkk., 2021). Selain itu, dikhawatirkan juga akan adanya kehilangan dalam pendidikan nilai moral dan karakter (character loss) anak yang merupakan salah satu tujuan pendidikan (UU No. 20 Tahun 2003). Penelitian ini dilakukan untuk mengetahui metode dan penerapan pendidikan nilai moral dan karakter yang dilakukan oleh Guru Kelas 1 di salah satu sekolah dasar di Kota Serang. Metode yang diterapkan pada penelitian ini adalah metode kualitatif dengan pendekatan deskriptif. Hasil penelitian ini menunjukan bahwa Guru menerapkan beberapa metode dalam pendidikan nilai moral dan karakter seperti penerapan peraturan kelas daring, penerapan peraturan ketika beristirahat, pembiasaan berdoa, pemberian hadis dan kata- kata bijak dan pemberian dorongan (encouragement). Kesimpulan dari penelitian ini adalah, perlunya kerjasama antara Guru dan orang tua dalam mengawasi penerapan dari pendidikan nilai moral dan karakter tersebut di rumah.
Kata kunci: Pendidikan Nilai Moral, Pendidikan Karakter, Pembelajaran Daring
Abstract. The long duration of online learning at home caused by the corona virus pandemic raises concerns about learning loss or reduced knowledge and learning skills of children (Andriani et al., 2021). In addition, it is also feared that there will be a loss in the education of children's moral values ​​and character which is one of the goals of education (Law No. 20 of 2003). This study was conducted to determine the method and application of moral values ​​and character education conducted by Class 1 teacher at an Elementary School in Serang City. The method applied in this research is a qualitative method with a descriptive approach. The results of this study indicate that the teacher applies several methods in the education of moral values ​​and character such as the application of online class rules, the application of rules before break time, the habit of praying, giving hadith and words of wisdom and giving encouragement by the teachers. The conclusion of this study is the need for cooperation between teachers and parents in supervising the implementation of moral values ​​and character education at home.
Differences in Halothane and Isofluran Anesthesia on Hemodynamic Status
Authors: Mustamu Alva Cherry , Nobel Bistara Difran , Susanti  
Published: November 2023

Background: Halothane and Isoflurane are two frequent inhalation agents used as maintenance anesthesia during surgery. After experiencing anesthesia, many patients experience decreased hemodynamic status as pressure blood, respiration, and pulse. Because that study this expected could determine proper anesthesia for use.
Purpose : evaluates differences in hemodynamic status post-anesthesia consequence use of halothane and isoflurane.
Method research: Study this is a study with quasi pre-post design experiment with a control group design. The sample study is all patients undergoing Installation Surgery at Sele Be Solu Hospital, Sorong City, which uses the general anesthesia technique with inhalation of halothane or isoflurane for as many as 21 people. Instrument study use sheet observation to measure pressure, blood, respiration, and pulse During surgery.
Research Results: The Wilcoxon test obtained a score of 0.157 on the pressure blood respondent after getting anesthesia halothane and respondents after getting anesthesia isoflurane, i.e., 0.007. significance of 1.000 and 0.317 on pulse respondents who got anesthesia halothane and isoflurane. Significance of 1.000 and 0.083 on respiration respondents who got anesthesia halothane and isoflurane. Mann Whitney test shows changes in blood pressure, pulse, and respiration in anesthetized respondents who used halothane and isoflurane score significance of 0.784, 0.576, and 0.307.
Conclusion: There is a difference in blood pressure at first and end anesthesia use of isoflurane. No, there is a difference in frequency pulse, initial pulse, and respiration anesthesia, and end anesthesia use isoflurane.No there is a difference in pressure blood, pulse, and respiration at the beginning and end anesthesia use halothane. There is no difference in blood pressure, pulse, and respiration after general anesthesia uses isoflurane and halothane.
Allah Algısı Açısından 4. ve 5. Sınıf DKAB Ders Programı ve Kitaplarının İncelenmesi
Authors: TAN Hümeyra Nazlı 
Published: November 2023

Allah algısı, çocukluk döneminde oluşmaya başlayan ve zamanla bireyin bütün hayatına etki edebilen oldukça önemli bir algı türüdür. Bu anlamda çocukluk döneminde Allah algısı ile ilgili verilen her türlü eğitim ve öğretim yaşantısı önem kazanmaktadır. Bununla birlikte Allah algısının Din Kültürü ve Ahlak Bilgisi (DKAB) ders programlarında ve kitaplarında nasıl oluşturulduğuna dair ayrıntılı çalışmalara henüz rastlanmamaktadır. Araştırma, bu eksikliği biraz olsun gidermek için DKAB ders programı ve kitaplarını Allah algısı açısından incelemektedir. Bu doğrultuda araştırmanın iki temel hedefi vardır. Birinci hedef, örgün eğitimde ilk defa DKAB dersi görmeye başlayan ve somut işlemler döneminde olan 4. ve 5. sınıf öğrencilerinin ders kitaplarında nasıl bir Allah tanımlaması ile karşılaştıklarını tespit etmektir. İkinci hedef ise bu tanımlamanın o yaş dönemindeki çocukların bilişsel ve duyuşsal gelişim düzeylerine uygun olup olmadığını ve çocukların olumlu yönde Allah algısı geliştirmelerine katkı sağlayıp sağlamadığını incelemektir.
Çalışma, nitel araştırma yöntemi ve içerik analizi tekniği ile yürütülmüştür. Araştırma materyalini, 4. ve 5. sınıf DKAB ders programı ve kitapları oluşturmaktadır. Önceden belirlenen dört temel kategori ve araştırma materyalinde Allah’ı tanımlamak için kullanılan ifadeler temel alınarak analiz işlemleri gerçekleştirilmiştir. Araştırmanın sonucuna göre 4. ve 5. sınıf DKAB ders programı ve kitaplarında içsel süreçler açısından çocuktaki Allah algısını olumlu yönde desteklemeye yönelik bilinçli bir stratejinin belirlenmediği ve İslam inancındaki Allah’a yönelik olumlu bağlanma figürlerine gerektiği kadar yer verilmediği tespit edilmiştir.
Prediction Ranifall Using Machine Learning Algorithms: Empirical Evidence from Bogura and Rangpur District of Bangladesh
Authors: Islam Md Rafiqul , Rahman Md Mostafizur , Afruz Afsana , Khalek Md Abdul , Rahman M Sayedur 
Published: November 2023

Around the world, forecasting rainfall has been regarded as one of the most difficult task. Exact and timely rainfall forecasting may be extremely helpful. By uncovering novel links between the readily available elements of historical data, data mining algorithms may accurately anticipate the amount of rainfall. Therefore, it remains intriguing to forecast rainfall data with both the highest degree of accuracy by combining and improving various data mining approaches in case of different weather stations. In this study we compare the forecasting performance of different data mining techniques such as Classification and Regression Trees (CART), Support Vector Machine (SVM), K-Nearest Neighbors (K-NN), Random Forest (RF), and Linear Discriminant Analysis (LDA) in case of Bogura and Rangpur district of Bangladesh. For this analysis, the monthly time series data from January 1964 to December 2017 are taken into account. For empirical investigations, the data mining process, including data collection, data pre-processing, modeling, and assessment, is closely adhered to. The empirical study shows that SVM approach is the best option for predicting rainfall in the case of both Bogura and Rangpur district, Bangladesh, for the next time period. The above study will be useful in providing information to support crop, water, and flood control, which will protect people's lives and property and promote economic in its growth.
International Journal of Statistical Sciences , Vol. 23(2), November, 2023, pp 47-62
High-sensitivity troponin T levels before and after cardiac surgery and the 30-day mortality: a retrospective cohort study
Authors: Liang Jian-Wei , Zhou Min , Jin Yong-Qiang , Li Ting-Ting , Wen Jiang-Ping 
Published: November 2023

BackgroundThe suggested threshold level of cardiac troponin T elevation after cardiac surgery is not very clear, and the values recommended by various guidelines and literature reports are quite different.MethodsIn this retrospective cohort study, we collected clinical data of patients who underwent heart surgery at Tsinghua University First Hospital between January 2015 and December 2022. Using the high-sensitivity cardiac troponin T levels (reference upper limit: 14 ng/L) measured at 1–3 days postoperation, the relationship between the cardiac troponin T level and the 30-day mortality risk was evaluated using Cox regression analysis.ResultsAmong the 3,128 patients included in this study, the types of operations mainly consisted of coronary artery bypass graft (CABG, 1,164, 37.2%), aortic valve replacement (AVR, 735, 23.5%), and other cardiac operations (1,229, 39.3%). Within 30 days postoperation, 57 patients (1.8%) died and 72 patients (2.3%) developed major vascular complications. In patients undergoing CABG or AVR, the cardiac troponin T threshold level measured within one day postoperation related to an increased 30-day mortality was determined to be 3,012 ng/L (95% CI: 1,435–3,578 ng/L), which is 218 times higher than the reference upper limit. In patients undergoing other cardiac operations, this threshold was 5,876 ng/L (95% CI: 2,458–8,119 ng/L), which is 420 times higher than the reference upper limit.ConclusionThe high-sensitivity cardiac troponin T level associated with an increased 30-day mortality risk after cardiac surgery is significantly higher than the current recommendations for defining clinically important perioperative myocardial injury.
Prominent muscle involvement in a familial form of mitochondrial disease due to a COA8 variant
Authors: Rimoldi Martina , Magri Francesca , Antognozzi Sara , Ripolone Michela , Salani Sabrina , Piga Daniela , Bertolasi Letizia , Zanotti Simona , Ciscato Patrizia , Fortunato Francesco , Moggio Maurizio , Corti Stefania , Comi Giacomo Pietro , Ronchi Dario 
Published: November 2023

Isolated mitochondrial respiratory chain Complex IV (Cytochrome c Oxidase or COX) deficiency is the second most frequent isolated respiratory chain defect. Causative mutations are mainly identified in structural COX subunits or in proteins involved in the maturation and assembly of the COX holocomplex. We describe an Italian familial case of mitochondrial myopathy due to a variant in the COX assembly factor 8 gene (COA8). Patient 1 is a 52-year-old woman who presented generalized epilepsy and retinitis pigmentosa at 10 years of age. From her early adulthood she complained about cramps and myalgia after exercise, and bilateral hearing loss emerged. Last neurological examination (52 years of age) showed bilateral ptosis, muscle weakness, peripheral neuropathy, mild dysarthria and dysphonia, cognitive impairment. Muscle biopsy had shown the presence of ragged-red fibers. Patient 2 (Patient 1’s sister) is a 53-year-old woman presenting fatigability, myalgia, and hearing loss. Neurological examination showed ptosis and muscle weakness. Muscle biopsy displayed a diffuse reduction of COX activity staining and ragged-red fibers. Both sisters presented secondary amenorrhea. After ruling out mtDNA mutations, Whole Exome Sequencing analysis identified the novel homozygous COA8 defect c.170_173dupGACC, p.(Pro59fs) in the probands. Loss-of-function COA8 mutations have been associated with cavitating leukoencephalopathy with COX deficiency in 9 reported individuals. Disease course shows an early-onset rapid clinical deterioration, affecting both cognitive and motor functions over months, followed by stabilization and slow improvement over several years. Our findings expand the clinical spectrum of COA8-related disease. We confirm the benign course of this rare disorder, highlighting its (intrafamilial) clinical variability.
The outcome and the risk factors of mucormycosis among patients with hematological diseases: a systematic and meta-analysis
Authors: Shen Meixiao , Wang Juan , Lei Meiqing , Wang Zhiming 
Published: November 2023

ObjectivesMucorale has come into a significant pathogen over recent decades. Nonetheless, mucormycosis-related mortality rates among patients with hematological disorders remain unascertained. Thus, we conducted a meta-analysis to determine mortality rates of mucormycosis in patients with hematology-related conditions.MethodsWe scoured PubMed, Embase, and Web of Science for original papers exploring the intersection of Mucormycosis and Hematological Diseases (from 2000 to 2022). We scrutinized the overall mortality across three distinct periods, as well as differentiating between high-income and middle-income nations. We further evaluated the pooled mortality and the risk differential (RD) across several subgroups.ResultsThe overall mortality rate for hematology patients with mucormycosis was 61%, within a 95% confidence interval (CI) of 0.54–0.68. A significant observation was that mortality rates were somewhat lower in high-income countries compared to middle-income countries (0.60 versus 0.64, p = 0.45). Importantly, we discovered that a combination of surgical and medical treatment significantly improved survival rates compared to medical treatment alone [mortality 0.49 versus 0.67, RD -0.19 (95%CI -0.38-0.00, I2 63.7%)]. As might be expected, disseminated mucormycosis posed a significantly higher risk of death compared to isolated mucormycosis [0.60 versus 0.57, RD death 0.16 (95%CI 0.03–0.28)]. Additionally, our analysis showed no discernible differences in survival rates between genders, between patients with and without breakthrough infection, between those who received mucor-active or mucor-inactive drugs prior to mucor infection, or between those on a multi-drug regimen and those on a single drug treatment.ConclusionDespite the high mortality rates associated with mucormycosis in patients with hematological disorders, those receiving both medical and surgical interventions, as well as those with isolated infection sites, exhibited improved survival outcomes. Conversely, factors such as gender, the presence of breakthrough infection, the use of mucor-active drugs before mucor infection, and multi-drug administration did not significantly influence patient outcomes.
The effects of prolonged stress exposure on the brain of rats and insights to understand the impact of work-related stress on caregivers
Authors: Pujo Jean Marc , Fitriani Dewi Yunia , Ben Saad Hajer , Ghariani Marwa , Dghim Amel , Mellouli Manel , Burin Antoine , Mutricy Remi , Houcke Stephanie , Roujansky Ariane , Mansyur Muchtaruddin , Nkontcho Flaubert , de Toffol Bertrand , Ben Amara Ibtissem , Kallel Hatem 
Published: November 2023

IntroductionStress exposure is a significant concern in the healthcare sector. This animal model study aims to reproduce caregivers’ working conditions and determine their impact on the brain.MethodTwenty-four healthy male rats of the Wistar strain were divided into four groups. Three groups were submitted each to one stressor for 21 days, while the fourth group was used as a control. Stressors were food and water deprivation (FW), permanent illumination (PI), and forced swimming (FS). At the end of the experiment, rats were euthanized, and stress biomarkers, biological parameters, and DNA damage were measured.ResultsProoxidant biomarker rates increased in the different groups (+50 to +75%) compared to the control (p &lt; 0.0001). Urinary corticosterone rates increased in all stressed animals, mainly in the PI group, with changes of up to +50% compared to the control group. Acetylcholinesterase levels decreased to −50% (p &lt; 0.0001 for the three exposed groups). Total ATPase, (Na+/K+)-ATPase, and Mg2+-ATPase activities decreased in all stressed groups. The percentage of brain cell congestion and apoptosis was 3% for the FW group (p &lt; 0.0001), 2% for the PI group (p &lt; 0.0001), and 4% for the FS group (p &lt; 0.0001) compared to the control (0.8%). DNA damage was observed in all exposed groups. Finally, we noticed behavioral changes and a depression-like syndrome in all stressed rats.ConclusionStressful conditions such as the working environment of caregivers can trigger several pathophysiological processes leading to oxidative, neurochemical, and hypothalamic–pituitary–adrenal disorders. These changes can progress to cell damage and apoptosis in the brain and trigger psychological and physical disorders.
Trophoblast glycoprotein is required for efficient synaptic vesicle exocytosis from retinal rod bipolar cells
Authors: Wakeham Colin M. , Shi Qing , Ren Gaoying , Haley Tammie L. , Duvoisin Robert M. , von Gersdorff Henrique , Morgans Catherine W. 
Published: November 2023

IntroductionRod bipolar cells (RBCs) faithfully transmit light-driven signals from rod photoreceptors in the outer retina to third order neurons in the inner retina. Recently, significant work has focused on the role of leucine-rich repeat (LRR) proteins in synaptic development and signal transduction at RBC synapses. We previously identified trophoblast glycoprotein (TPBG) as a novel transmembrane LRR protein localized to the dendrites and axon terminals of RBCs.MethodsWe examined the effects on RBC physiology and retinal processing of TPBG genetic knockout in mice using immunofluorescence and electron microscopy, electroretinogram recording, patch-clamp electrophysiology, and time-resolved membrane capacitance measurements.ResultsThe scotopic electroretinogram showed a modest increase in the b-wave and a marked attenuation in oscillatory potentials in the TPBG knockout. No effect of TPBG knockout was observed on the RBC dendritic morphology, TRPM1 currents, or RBC excitability. Because scotopic oscillatory potentials primarily reflect RBC-driven rhythmic activity of the inner retina, we investigated the contribution of TPBG to downstream transmission from RBCs to third-order neurons. Using electron microscopy, we found shorter synaptic ribbons in TPBG knockout axon terminals in RBCs. Time-resolved capacitance measurements indicated that TPBG knockout reduces synaptic vesicle exocytosis and subsequent GABAergic reciprocal feedback without altering voltage-gated Ca2+ currents.DiscussionTPBG is required for normal synaptic ribbon development and efficient neurotransmitter release from RBCs to downstream cells. Our results highlight a novel synaptic role for TPBG at RBC ribbon synapses and support further examination into the mechanisms by which TPBG regulates RBC physiology and circuit function.