bluuebunny/crossref_metadata_2025_split huggingface dataset:
Global observational coverage of onshore oil and gas methane sources with TROPOMI
Authors: Gao Mozhou , Xing Zhenyu , Vollrath Coleman , Hugenholtz Chris H. , Barchyn Thomas E. 
Published: October 2023

AbstractSatellite observations have been used to measure methane (CH4) emissions from the oil and gas (O&G) industry, particularly by revealing previously undocumented, very large emission events and basin-level emission estimates. However, most satellite systems use passive remote sensing to retrieve CH4 mixing ratios, which is sensitive to sunlight, earth surface properties, and atmospheric conditions. Accordingly, the reliability of satellites for routine CH4 emissions monitoring varies across the globe. To better understand the potentials and limitations of routine monitoring of CH4 emissions with satellites, we investigated the global observational coverage of the TROPOMI instrument onboard the Sentinel-5P satellite—the only satellite system currently with daily global coverage. A 0.1° × 0.1° gridded global map that indicates the average number of days with valid observations from TROPOMI for 2019–2021 was generated by following the measurement retrieval quality-assurance threshold (≥ 0.5). We found TROPOMI had promising observational coverage over dryland regions (maximum: 58.6%) but limited coverage over tropical regions and high latitudes (minimum: 0%). Cloud cover and solar zenith angle were the primary factors affecting observational coverage at high latitudes, while aerosol optical thickness was the primary factor over dryland regions. To further assess the country-level reliability of satellites for detecting and quantifying CH4 emissions from the onshore O&G sector, we extracted the average annual TROPOMI observational coverage (TOC) over onshore O&G infrastructure for 160 countries. Seven of the top-10 O&G-producing countries had an average annual TOC < 10% (< 36 days per year), which indicates the limited ability to routinely identify large emissions events, track their duration, and quantify emissions rates using inverse modelling. We further assessed the potential performance of the latter by combining TOC and the uncertainties from the global O&G inventory. Results indicate that the accuracy of emissions quantifications of onshore O&G sources using TROPOMI data and inverse modeling will be higher in countries located in dryland and mid-latitude regions and lower in tropical and high-latitude regions. Therefore, current passive-sensing satellites have low potential for frequent monitoring of large methane emissions from O&G sectors in countries located in tropical and high latitudes (e.g., Canada, Russia, Brazil, Norway, and Venezuela). Alternative methods should be considered for routine emissions monitoring in these regions.
Sustainable development, eco-tourism carrying capacity and fuzzy algorithm-a study on Kanas in Belt and Road
Authors: Yu Kui , Gao Han 
Published: October 2023

AbstractIn this paper, the method of fuzzy pattern recognition is adopted in more precisely evaluating the actual state of eco-tourism development regarding a given tourist destination in comparison with the three standard patterns (saturated/optimal/deficient) of development degree. The research process is as follows: Firstly, the indictors of carrying capacity of a tourist destination and the corresponding measuring factors are established; secondly, an assessment group is recruited to work out the most constraining factors among the measuring factors; thirdly, by means of field survey, numerical values of the actual state are acquired; fourthly, there comes out the membership vectors and the membership matrix of the standard patterns corresponding to the vectors of three standard patterns, threshold and the actual state; Finally, it could be identified which standard pattern that the actual state is closest to via the lattice degrees of proximity. An exemplary case study on Kanas National Nature Reserves is attached to the logic calculus. This paper is contributed to dynamically monitor the threshold of tourism carrying capacity and precisely identify which carrying capacity (spatial resource/ecological environment/economic resources/people’s psychology/socio-culture) with potential risks.
New opto-electro-mechanical sensor for two-dimensions dosimetry based on radiochromic films
Authors: Mena S. , Karkour N. , Alaphilippe V. , Botero J. P. , Jiménez M. , Linget D. , Gibelin L. , Le Ven V. , Marquet A. , Mellouh S. , Josson E. , Benassou W. , Muñoz-Berbel X. , Guirado G. , Guardiola C. 
Published: October 2023

AbstractThis work presents the validation of a new Opto‒Electro-Mechanical (MOEM) system consisting of a matrix of photodetectors for two-dimensional dosimetry evaluation with radiochromic films. The proposed system is based on a 5 × 10 matrix of photodetectors controlled by both in-house electronic circuit and graphical user interface, which enables optical measurements directly. We present the first tests performed in an X-ray machine and 137Cs source with that array by using Gafchromic EBT3 films. We obtained similar results than with a standard method (e.g. flat-bed scanner). Results were compared with Monte Carlo simulations and very good agreement was found. Results show the feasibility of using this system for dose evaluations. To the best of our knowledge, this is the first MOEM sensor for radiotherapy. Further developments are ongoing to create an advanced 16 × 16 LDRs system covering 1.6 cm × 1.6 cm with a 1 mm of spatial resolution. We point to develop a portable dosimetry tool delivering dose maps in real time to improve the clinical application of radiochromic films.
Association between breast diseases and symptomatic uterine fibroids by using South Korean National Health Insurance database
Authors: Yuk Jin-Sung , Yang Seung-Woo , Yoon Sang-Hee , Kim Myoung Hwan , Seo Yong-Soo , Lee Yujin , Joo Yilseok , Kim Jungbin , Yoon Sam-Youl , Cho Hyunjin , Yang Keunho , Gwak Geumhee 
Published: October 2023

AbstractBoth the uterus and breasts have sex hormone dependence, yet there are few studies on the association between breast disease and uterine fibroids (UFs). The purpose of this study was to investigate the incidence of benign breast disease (BBD), carcinoma in situ (CIS), and breast cancer (BC) in women treated for UFs compared to women who were not treated for UFs. This retrospective cohort study used national health insurance data from January 1st, 2011, to December 31st, 2020. We selected women between 20 and 50 years old who (1) were treated for UFs (UF group) or (2) visited medical institutions for personal health screening tests without UFs (control group). We analyzed independent variables such as age, socioeconomic status (SES), region, Charlson comorbidity index (CCI), delivery status, menopausal status, menopausal hormone therapy (MHT), endometriosis, hypertension (HTN), diabetes mellitus (DM), and dyslipidemia based on the first date of uterine myomectomy in the UF group and the first visiting date for health screening in the non-UF group. There were 190,583 and 439,940 participants in the UF and control groups, respectively. Compared with those of the control group, the RRs of BBD, CIS, and BC were increased in the UF group. The hazard ratios (HRs) of BBD, CIS, and BC in the UF group were 1.335 (95% confidence interval (CI) 1.299–1.372), 1.796 (95% CI 1.542–2.092), and 1.3 (95% CI 1.198–1.41), respectively. When we analyzed the risk of BC according to age at inclusion, UFs group had the increased risk of BCs in all age groups in comparison with control group. Women with low SES (HR 0.514, 95% CI 0.36–0.734) and living in rural areas (HR 0.889, 95% CI 0.822–0.962) had a lower risk of BC. Our study showed that women with UFs had a higher risk of BBD, CIS, and BC than those without UFs. This result suggests that women with UFs should be more conscious of BC than those without UFs. Therefore, doctors should consider recommending regular breast self-exams, mammography, or ultrasound for the early detection of BC in women with UFs.
Examining factors that influence medication adherence with children seen at outpatient department in Western China: a cross-sectional survey
Authors: Yang Chunsong , Yang Yaya , Zhang Lingli , Li Dan 
Published: October 2023

AbstractWe aimed to evaluate the prevalence of medication adherence, assess the association between guardians’ mental health and medication adherence for children seen at outpatient department from western China, and identify characteristics associated with nonadherence. We conducted a cross-sectional survey. Participants were recruited by consecutive sampling from the outpatient of the West China Second Hospital from October 2021 to April 2022. The Morisky Medication Adherence Scale (MMAS-8) was used to evaluate patients’ medication adherence. A multivariate linear regression model was used to analyze influencing factors. 1206 children with a mean age of 6.02 ± 3.86 years were included. Seventeen percent (208/1206) of patients showed good adherence, 24.7% (298/1206) showed moderate adherence, and 58% (700/1206) showed poor adherence. Thirty-five percent (428/1206) of guardians had anxiety. Factors that influenced medication adherence included anxiety score of guardian (P = 0.030), education level of guardian (P = 0.003), annual household income (P = 0.001), and days the patient is on the medication (P = 0.023). A majority of children seen at outpatient department from West China had low medication adherence, and depression and anxiety among guardians were common. Implementing health education measures will be important for improving medication adherence in future.
Metabolic profiling to evaluate the impact of amantadine and rimantadine on the secondary metabolism of a model organism
Authors: Kostina-Bednarz Marianna , Płonka Joanna , Barchanska Hanna 
Published: October 2023

AbstractMetabolic profiling offers huge potential to highlight markers and mechanisms in support of toxicology and pathology investigations during drug development. The main objective was to modify therapy with adamantane derivatives: amantadine and rimantadine, to increase their bioavailability and evaluate the influence of such therapy on drug metabolism using Saccharomyces cerevisiae as the model organism. In this study, the profile of endogenous metabolites of a model organism was measured and interpreted to provide an opportunity to investigate changes induced by treatment with amantadine and rimantadine. It was found that resveratrol supplementation synergistically enhanced the effects of amantadine treatment and increased rimantadine metabolism, potentially reducing side effects. The fingerprinting strategy was used as an efficient technique for qualitatively evaluating and monitoring changes in the profiles of endogenous components and their contents in a model organism. Chemometric tools were employed to find marker compounds that can be defined as characteristic indicators of a pharmacological response to a therapeutic intervention. An improved understanding of the mechanisms involved in drug effect and an increased ability to predict individual variations in the drug response of organisms will improve the treatment process and the development of new therapies.
In-situ micro-CT scanning and compressive strength assessment of diammonium hydrogen phosphate (DAP) treated chalk
Authors: Samarkin Yevgeniy , Amao Abduljamiu Olalekan , Aljawad Murtada Saleh , Borji Mostafa , Scott Norman , AlTammar Murtadha J. , Alruwaili Khalid M. 
Published: October 2023

AbstractThe occurrence of wellbore mechanical failure is a consequence of the interaction among factors such as in situ stress, rock strength, and engineering procedures. The process of hydrocarbons production, causing reduction of pore pressure, alters the effective stresses in the vicinity of a borehole, leading to borehole instability issues. Estimating the rocks’ elastic modulus and compressive strength is essential to comprehend the rock matrix’s mechanical response during drilling and production operations. This study aimed to assess the practicality of Diammonium Hydrogen Phosphate (DAP) application as a chemical for strengthening chalk in hydrocarbon reservoirs, to make it resistant to high stresses and failure during drilling and production. The mechanical and physical properties of Austin chalk rock samples treated with DAP under mimicked reservoir conditions were studied. The results showed that DAP is a highly effective carbonate rock consolidating agent that improves the mechanical strength of the chalk. Compressive test measurements conducted on rocks treated at two different temperatures (ambient and 50 °C) showed that DAP effectively strengthened the rock matrix, resulting in an increase in its compressive strength (22–24%) and elastic modulus (up to 115%) compared to the untreated sample. The favorable outcomes of this research suggest that the DAP solution holds promise as a consolidation agent in hydrocarbon reservoirs. This contributes to the advancement of knowledge regarding effective strategies for mitigating mechanical failures of the wellbore during drilling and production.
Anticipating older populations’ health risk exacerbated by compound disasters based on mortality caused by heart diseases and strokes
Authors: Gao Shangde , Wang Yan 
Published: October 2023

AbstractThe health of older populations in the Southeastern U.S. receives threats from recurrent tropical cyclones and extreme heat, which may exacerbate the mortality caused by heart diseases and strokes. Such threats can escalate when these extremes form compound disasters, which may be more frequent under climate change. However, a paucity of empirical evidence exists concerning the health threats of compound disasters, and anticipations regarding the health risks of older populations under future compound disaster scenarios are lacking. Focusing on Florida, which has 67 counties and the second-largest proportion of older populations among U.S. states, we calibrate Poisson regression models to explore older populations’ mortality caused by heart diseases and strokes under single and compound disasters. The models are utilized to estimate the mortality across future disaster scenarios, the changing climate, and the growing population. We identify that under multiple hurricanes or heat, current-month hurricanes or heat can affect mortality more heavily than previous-month hurricanes or heat. Under future scenarios, co-occurring hurricanes and extreme heat can exacerbate the mortality more severely than other disaster scenarios. The same types of compound disasters can coincide with an average of 20.5% higher mortality under RCP8.5-SSP5 than under RCP4.5-SSP2. We assess older populations’ future health risks, alerting health agencies to enhance preparedness for future “worst-case” scenarios of compound disasters and proactively adapt to climate change.
A comparison of language control while switching within versus between languages in younger and older adults
Authors: de Bruin Angela , Kressel Heidi , Hemmings Daisy 
Published: October 2023

AbstractWord retrieval during language production slows down with age. However, bilinguals also require language control to manage language competition, in particular when switching languages to cues. The current study examined how this bilingual language control differs between younger and older adults. It also compared bilingual control, and age-group differences, to control that might be applied when alternating between responses within one language. In Experiment 1, 40 younger and 40 older monolingual adults completed a task alternating between noun and verb responses to pictures. The task showed costs associated with language control but these did not differ between age groups. Experiment 2 was completed by 50 older and 50 younger bilingual adults. Older adults showed larger switching costs than younger adults when switching between and within languages, suggesting they experienced more difficulty with reactive control. However, while older adults showed larger mixing costs than younger adults when using two languages in the dual-language environment relative to the single-language environment, they surprisingly showed smaller mixing costs than younger adults in the noun-verb within-language naming task. These findings show that language control, and the way it differs between older and younger adults, is not the same across within- and bilingual-language competition.
Height detection of crop divider toes of sugarcane harvester based on Kalman adaptive adjustment
Authors: Wen Chunming , Yan Yunzhi , Wu Wanling , Li Jianheng , Hou Bingxu , Cui Wenxuan , Huang Youzong , Li Kaihua , Long Xiaozhu , Nong Hongliang 
Published: October 2023

AbstractCrop divider toes are an essential device of sugarcane harvester. Moving forward against the ground is a critical way to improve the harvesting rate of lodged sugarcane. Height detection is the basis for precise control of crop divider toes moving forward against the ground. Due to the current problem of operating difficulties in manually adjusting the height of crop divider, a height detection system based on a millimeter wave radar sensor was designed to detect the height of crop divider toes from the ground. This paper proposed a height detection method of crop divider toes for sugarcane harvester based on Kalman adaptive adjustment. The data measured by the sensor was pretreated to determine whether the height had changed. Reset the Kalman filter and adjust the parameters when changes occur to improve the filter response speed and ranging accuracy. To adapt to the scenario of quickly adjusting the height of crop divider during the traveling process of sugarcane harvester. A one-way ANOVA test and a two-way ANOVA test were conducted on a simulated test platform. The results of the one-way ANOVA test showed that both forward speed and vegetation cover thickness had a significant effect on height detection accuracy. The results of the two-way ANOVA test showed that the interaction of forward speed and vegetation cover thickness did not have a significant effect on ranging accuracy. It was verified through experiments that both the ranging accuracy and the response speed of height change were significantly improved after the processing of the method in this paper. The mean square error after processing was lower than 2.5 cm. The feasibility of the height detection system was verified by field trials. The results of this study will provide a reference for the design of automatic elevation of crop divider.
Alum and a TLR7 agonist combined with built-in TLR4 and 5 agonists synergistically enhance immune responses against HPV RG1 epitope
Authors: Mashhadi Abolghasem Shirazi Maryam , Sadat Seyed Mehdi , Haghighat Setareh , Roohvand Farzin , Arashkia Arash 
Published: October 2023

AbstractTo relieve the limitations of the human papillomavirus (HPV) vaccines based on L1 capsid protein, vaccine formulations based on RG1 epitope of HPV L2 using various built-in adjuvants are under study. Herein, we describe design and construction of a rejoined peptide (RP) harboring HPV16 RG1 epitope fused to TLR4/5 agonists and a tetanus toxoid epitope, which were linked by the (GGGS)3 linker in tandem. In silico analyses indicated the proper physicochemical, immunogenic and safety profile of the RP. Docking analyses on predicted 3D model suggested the effective interaction of TLR4/5 agonists within RP with their corresponding TLRs. Expressing the 1206 bp RP-coding DNA in E. coli produced a 46 kDa protein, and immunization of mice by natively-purified RP in different adjuvant formulations indicated the crucial role of the built-in adjuvants for induction of anti-RG1 responses that could be further enhanced by combination of TLR7 agonist/alum adjuvants. While the TLR4/5 agonists contributed in the elicitation of the Th2-polarized immune responses, combination with TLR7 agonist changed the polarization to the balanced Th1/Th2 immune responses. Indeed, RP + TLR7 agonist/alum adjuvants induced the strongest immune responses that could efficiently neutralize the HPV pseudoviruses, and thus might be a promising formulation for an inexpensive and cross-reactive HPV vaccine.
Crowdsourced audit of Twitter’s recommender systems
Authors: Bouchaud Paul , Chavalarias David , Panahi Maziyar 
Published: October 2023

AbstractThis research conducts an audit of Twitter’s recommender system, aiming to examine the disparities between users’ curated timelines and their subscription choices. Through the combined use of a browser extension and data collection via the Twitter API, our investigation reveals a high amplification of friends from the same community, a preference for amplifying emotionally charged and toxic tweets and an uneven algorithmic amplification across friends’ political leaning. This audit emphasizes the importance of transparency, and increased awareness regarding the impact of algorithmic curation.
Accuracy of intraoral scanning versus conventional impressions for partial edentulous patients with maxillary defects
Authors: Cao Rongkai , Zhang Shilei , Li Lishan , Qiu Piaopiao , Xu Hui , Cao Yujie 
Published: October 2023

AbstractThis study aimed to evaluate the accuracy of digital dental impressions obtained by intraoral scanning (IOS) for partial edentulous patients with maxillary defects by comparing them with conventional impression techniques. Ten subjects underwent an experimental procedure where three ceramic blocks were affixed to the healthy palate mucosa. Digital dental impressions were captured using IOS and subsequently imported into software. Conventional impressions obtained by silicone rubber were also taken and scanned. Linear distance and best-fit algorithm measurements were performed using conventional impression techniques as the reference. Twenty impressions were analyzed, which included 30 pairs of linear distances and 10 best-fit algorithm measurements. Regarding linear distance, paired two-sample t-test demonstrated no significant differences between IOS and model scanning in groups A and C, whereas significant differences were found in group B (P < 0.05). Additionally, ANOVA revealed significant differences among the groups (P < 0.05). No significant differences were found for the best-fit algorithm measurement of the dentition. IOS can provide accurate impressions for partial edentulous patients with maxillary defects and its accuracy was found to be comparable with conventional impression techniques. A functional impression may be needed to ensure accurate reproduction of soft and hard tissues in defect or flap areas.