bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cyclization reactions of ω‐tosyloxy‐1‐alkynyl‐ and ω‐tosyloxy‐1‐alkenylborates and their ω‐halo analogues
Authors: Negishi Ei‐ichi , Nguyen Thinh , Boardman Larry D. , Sawada Hiroyuki , Morrison James A. 
Published: January 2005

AbstractThe reaction of trialkylboranes with ω‐tosyloxy‐1‐lithio‐1‐alkynes can induce transfer of an alkyl group from the boron atom to the alkynyl carbon atom with concomitant formation of four‐ through six‐membered carbocycles via intramolecular displacement of the ω‐tosyloxy group. The stereoselectivity of the reaction, however, is low (anti/syn≃1.6–1.7). The corresponding reaction of ω‐halo‐ or ω‐tosyloxy‐1‐alkenylborates also gives exocyclic alkenes via 1,2‐migration‐cyclization followed by dehydroboration. In the cases of cyclopropanation, cyclopropylcarbinyl‐to‐homopropargyl rearrangement rather than dehydroboration takes place. Diphenylzirconocene reacts similarly with 6‐lithio‐5‐hexynyl tosylate to give phenylmethylenecyclopentane in 45% yield. On the other hand, attempts to induce a similar migration with phenyl derivatives of Y, V, Cr, and Mn have led to < 5–10% yields of the same cyclization product.
X‐Ray determination of the effective charges on sulfur and phosphorus atoms in chemical compounds
Authors: Dolenko G. N. , Litvin A. L. , Elin V. P. 
Published: January 2005

AbstractThe dependencies of Kα line shifts of the P and S atoms on effective charges of the atoms, calculated by CNDO/S, CNDO/2, INDO, and MNDO methods in the minimal and extended basis sets, have been investigated for model compounds. Good linear relationships between Kα shifts and atomic charges have been obtained for all cases investigated except for CNDO/2 and INDO calculations in the extended basis set. It is found that the PS bond ionicity is a nearly constant value, whereas the PS bond ionicity increases linearly with an increase in the positive charge of the central P atom. It is shown that the P and S atom charge in sulfides and phosphines containing no substituents with a strong M‐effect at the central atom depend only on inductive substituent effects. Also, the positive charge on the central atom increases with the growth of the π‐donor properties of substituents in sulfides and phosphines containing substituents exerting a strong M‐effect, as well as in phosphoryl and thiophosphoryl compounds and sulfones.
Substitution of 2‐phosphaindolizines by bromine and by chlorophosphines
Authors: Bansal Raj K. , Gupta Neelima , Kabra Vijaya , Spindler Claudia , Karaghiosoff Konstantin , Schmidpeter Alfred 
Published: January 2005

AbstractBromine does not add to phosphorus in a 2‐phosphaindolizine 1 but substitutes its 1‐position. The 1‐bromo derivatives 2 are best prepared with Br2/NEt3 or N‐bromosuccinimide. Their hydrolysis is remarkable; it involves a debromination of C‐1, an oxidation of P and a selective opening of the P/C‐3 bond.PCl3 also causes a substitution of the 1‐position. The resulting 1‐dichlorophosphino derivatives 5 easily undergo a substituent exchange at the exocyclic phosphorus. More 1‐phosphino derivatives are formed in the reaction of 1 with phenyl and diazaphospholyl dichlorophosphine.
Preparation of polyfluorodihydrobenzothiophenes and investigation of some of their chemical properties
Authors: Maksimov Alexander M. , Platonov Vyacheslav E. 
Published: January 2005

AbstractCo‐pyrolysis of thiophenol or diphenyl disulfide with tetrafluoroethylene or chlorotrifluoroethylene in the presence of oxidants gave 2,2,3,3‐tetrafluoro‐2,3‐dihydrobenzo[b]thiophene (I) or the corresponding chlorotrifluorodihydrobenzothiophenes.Reactions of compounds synthesized by use of electrophilic and nucleophilic reagents and with oxidants have been studied.
NMR studies on the ligand exchange reactions between diaryl tellurides and phenyllithium: Detection of hypervalent triaryl tellurium ate complexes
Authors: Ogawa Satoshi , Masutomi Yutaka , Furukawa Naomichi , Erata Tomoki 
Published: January 2005

AbstractDiaryl tellurides undergo rapid ligand exchange and disproportionation reactions on treatment with phenyllithium at −78°C. Triarylteliuranes [10‐Te‐3(C3)]− Li+ were identified as discrete intermediates during the reactions by 125Te, 1H, 13C, and CH‐COSY NMR studies.
Coupling reactions of 2‐aryl‐1,3‐dithiolane‐S‐oxides with MeMgl
Authors: Cheng Wen‐Lung , Luh Tien‐Yau 
Published: January 2005

AbstractReactions of 2‐aryl‐1,3‐dithiolane‐S‐oxides 1 with MeMgl in refluxing benzene‐ether furnish a useful procedure for introducing the isopropenyl group. The reaction may proceed via a fragmentation‐coupling process leading to the alkylative olefination product.
Reductive ring opening of cyclopropyl ketones with samarium (II) diiodide
Authors: Kim Yong Hae , Lee In Sang 
Published: January 2005

AbstractFunctionalized cyclopropyl ketones have been found to undergo facile reductive cyclopropane ring opening with samarium (II) diiodide in the presence of a proton source. These reactions were exceedingly rapid, taking place in most cases at −78°C under neutral conditions. An ester group substituted at the C2 position of the cyclopropane ring played an important role in the ring opening of cyclopropyl ketones.
Synthesis of flavins bearing a sulfur functional group and their catalytic activities for reduction of disulfides
Authors: Nagata Toshiyuki , Fujimori Ken , Oae Shigeru 
Published: January 2005

AbstractBis‐flavins, each of which bears a disulfide linkage in the molecule, have been synthesized as model compounds for dihydronicotinamide dependent disulfide reductase. These flavins were found to be much better catalysts to promote the reduction of dibenzyl disulfide to α‐toluenethiol than 3‐methyllumiflavin.
Cyclization of N‐propargylaminophosphines—New method for synthesis of 2,5‐dihydro‐1,2‐azaphospholes
Authors: Angelov Christo M. , Enchev Dobromir D. 
Published: January 2005

AbstractThe reaction of N‐methyl‐N‐propargylamine with dialkoxy‐chlorophosphines 1a–e gave N‐dialkoxyphosphinyl‐N‐propargylammonium salts 2a–e which, by heating, undergo cyclization to new five‐membered azaphosphole derivatives 4a–e.
2,6‐Dithiodecahydro‐1H,5H‐Diimidazo[4,5,‐b:4′,5′‐e]Pyrazine and related dioxo‐ and diimino‐decahydrodiimidazopyrazines
Authors: Vedachalam Murugappa , Boyer Joseph H. 
Published: January 2005

AbstractThiourea condensed with 1,4‐diformyl‐2,3,5,6‐tetrahydroxypiperazine 2 in the presence of hydrochloric acid to give 2,6‐dithiodecahydro‐1 H,5H‐diimidazo[4,5,‐b:4′,5′‐e]pyrazine 5 isolated as the dihydrochloride salt. The salt 5. 2HCl was converted to the free base 5 by lithium hydroxide, to the dinitrate salt 5. 2HNO3 by silver nitrate, degraded to 2‐thio‐2,3,4,7‐tetrahydro‐1 H‐imidazo[4,5‐b]pyrazine 6 in a reaction with tert‐butyl amine, and converted to 4,8‐dihydro‐4,8‐dinitro‐1H,5H‐diimidazo[4,5‐b:4′,5′‐e]pyrazine‐2,6‐ disulfonic acid 9 by nitric acid (100%) at −40°C. Denitration of the dinitramine 9 to give 4,8‐dihydro‐1H,5H‐diimidazo[4,5‐b:4′,5′‐e]pyrazine 11 was brought about by methanolic hydrogen chloride in ether. In one run nitration without oxidation converted the salt 5 · 2HCl to the dinitrate salt of the 4,8‐dinitro derivative 10; treatment with triethyl amine liberated the free base 10 from the salt. Degradation of 2,6‐dioxo‐1,3,4,5,7,8‐hexanitrodecahydro‐1H,5H‐diimidazo[4,5‐b:4′,5′‐e]pyrazine 12 to 2‐oxo‐2,3‐dihydro‐1,3‐dinitro‐1H‐imidazo[4,5‐b] pyrazine 13 was brought about by hydrochloric acid. Treatment with lithium hydroxide also liberated 2,6‐dioxodecahydro‐1H,5H‐diimidazo [4,5‐b:4′,5′‐e]pyrazine 3 from its dihydrochloride salt. Attempts to liberate 2,6‐diiminodecahydro‐1H, 5H‐diimidazo[4,5‐b:4′,5′‐e]pyrazine 4 from its tetrahydrochloride salt led instead to intractable mixtures. The tetrahydrochloride salt 4 · 4HCl was converted to the dihydrochloride salt 4 · 2HCl in a reaction with tert‐butyl amine.
P‐Substituted 3‐phosphabicyclo [3.1.0] hexane 3‐oxides from diastereoselective substitution at phosphorus
Authors: Keglevich György , Kovács Attila , Tőke László , Újszászy Kálmán , Argay Gyula , Czugler Mátyás , Kálmán Alajos 
Published: January 2005

AbstractPreparation of P‐amino‐3‐phosphabicyclo[3.1.0]‐hexane 3‐oxides either by addition of dichlorocarbene to the double bond of 1‐amino‐2,5‐dihydro‐1H‐phosphole 1‐oxides or by substitution of the P‐chloro derivative of the bicyclic system was accomplished. Two different diastereomers are obtained by the two approaches; their 13C NMR spectra were interpreted on the basis of the P‐ethoxy isomers, whose structures were confirmed by X‐ray analysis. The P‐hydroxy adduct was also prepared, and it was found that intermolecular OH … O hydrogen bonding connects the molecules together in the solid phase. This effect eliminates the possibility of diastereoisomerism, as was also observed in the case of P‐hydroxy tetrahydrophosphinine oxides. Thermolysis of the P‐hydroxy adduct is a better way to synthesize 1‐hydroxy‐1,2‐dihydrophosphinine oxides than by hydrolysis of the phosphinic chlorides.
Synthesis, characterization, and X‐ray crystallographic structure of 1,3‐dimethyl‐2(3H)‐imidazoleselone
Authors: Williams Daniel J. , Fawcett‐Brown Melissa R. , Raye Rhonda R. , VanDerveer Donald , Pang Yong T. , Jones Robert L. , Bergbauer Katrina L. 
Published: January 2005

AbstractThe reaction of elemental Se with 1,3‐dimethylimidazolium iodide in methanolic K2CO3 yields 1,3‐dimethyl‐2(3H)‐imidazoleselone for which three addition products, two with bromine and one with iodomethane, have been synthesized and for which X‐ray crystallographic analysis shows the structure to consist of a selenium‐substituted planar heterocyclic ring with bond distances and angles significantly different from those noted for the previously reported sulfur analog [1,3‐dimethyl‐2(3H)‐imidazolethione, dmit]. Crystal data: C5H8N2Se, space group C mcm, M = 175.03, a = 8.625(3), b = 11.447(6), c = 6.900(4) Å, V = 681.24 Å3, Z = 4, Dc = 1.707 g cm−3, D0 = 1.68 g cm−3, λ = 0.71073 Å (Mo‐Kα), μ = 5.35 mm−1, R = 0.034, and Rw = 0.031.
Kinetic studies of hydrolysis of some alkyl benzenesulfinates
Authors: Okuyama Tadashi 
Published: January 2005

AbstractHydrolysis reactions of methyl, ethyl, isopropyl, and t‐butyl benzenesulfinates were kinetically investigated. Rates of alkaline hydrolysis decrease with increasing steric effects (Me > Et > i‐Pr > t‐Bu), while the t‐butyl ester is the most reactive in perchloric acid (t‐Bu > Me > Et > i‐Pr). The hydrolysis is faster in HCl and HBr than in HClO4, and the relative rates in the halide acids are not unusual (Me > Et > i‐Pr ∼ t‐Bu). The high reactivity of the t‐butyl ester in HClO4, is ascribed to the reaction at the carbon via the A1 mechanism, while halide ions accelerate the hydrolysis by nucleophilic participation at sulfur.
Stereoselective sulfur extrusion reaction of syn‐ and anti‐10,20‐dibromo‐2,3,12,13‐tetrathia[4.4]metacyclophanes to the corresponding syn‐ and anti‐dithia[3.3]metacyclophanes
Authors: Fujihara Hisashi , Chiu Jer‐Jye , Furukawa Naomichi 
Published: January 2005

AbstractA new cyclophane, 10,20‐dibromo‐2,3,12,13‐tetrathia[4.4]metacyclophane (1), has been synthesized by the oxidative coupling reaction of 2,6‐bis(mercaptomethyl)‐1‐bromobenzene with I2. Both syn and anti isomers of 1 can be isolated at room temperature. The thermal sulfur extrusion reaction of anti‐1 with (Et2N)3P afforded anti‐9,18‐dibromo‐2,11‐dithia[3.3]metacyclophane, while syn‐1 gave 9,19‐dibromo‐2,11,12‐trithia[3.4]metacyclophane. syn‐9,18‐Dibromo‐2,11‐dithia[3.3]metacyclophane was produced from the photochemical sulfur extrusion of syn‐1 with (MeO)3P.
Formation of allyl‐substituted allene episulfide S‐oxides and their thermal and acid‐catalyzed rearrangements
Authors: Choi Nami , Tokitoh Norihiro , Ando Wataru 
Published: January 2005

AbstractOxidation of allyl‐substituted allene episulfides with a peracid gave the corresponding allene episulfide S‐oxides which were found to undergo ready isomerization to bicyclo[2.1.1]thiahexane S‐oxide derivatives on thermolysis or under acid‐catalyzed reaction conditions.
Chlorodiazaphospholines as intermediates in the synthesis of 1,2‐dihydro‐2‐alkenyl‐3H‐pyrazol‐3‐ones and 2‐pyrrolylacetates
Authors: Baccolini Graziano , Biondi Daniele 
Published: January 2005

AbstractNew derivatives of 1,2‐dihydro‐2‐alkenyl‐3H‐pyrazol‐3‐ones 6 and 7 have been synthesized at room temperature by a one‐pot two‐step reaction of PCl3, a ketone methylhydrazone, and a β‐keto ester. With ketone methylhydrazones bearing at least a phenyl group in the α‐positions to the CN bond and in the second step β‐keto esters, such as propionyl‐ or butyrylacetates, we obtained 2‐pyrrolylacetates 8 as unexpected products together with pyrazolones 7. The ratio of the two products depends on the nature of the groups in the α‐positon to the CN bond. A chlorodiazaphospholine 1 is the key intermediate of this new reaction, and a plausible mechanism of formation of the azaheterocycles is reported.
Phosphonic systems. Part 12. Fragmentation‐rearrangement of dialkyl 2‐acyloxyalkylphosphonates
Authors: de Jongh Connie P. , Modro Tomasz A. , Modro Agnes M. 
Published: January 2005

AbstractDialkyl esters of 2‐acyloxyalkylphosphonic acids, RCH(OAc)CH2PO3R′2, undergo thermolytic fragmentation to an alkene RCHCH2, a new ester AcOR′, and an alkyl metaphosphate R′OPO2. The reaction represents a new type of a process in which a metaphosphate species is generated from a neutral precursor and involves alkyl group (R′) migration as a prerequisite for the reaction. Mechanistic studies indicate that the reaction involves interaction between the phosphoryl group and the electrophilic center of the Ac group, followed by the intramolecular dealkylation of the POR′ function and the subsequent fragmentation of the intermediate.
Syntheses of β‐amidovinyltellurides and oxazoles by addition reactions of alkynes with benzenetellurinyl trifluoromethanesulfonate in acetonitrile
Authors: Fukumoto Takahiro , Aso Yoshio , Otsubo Tetsuo , Ogura Fumio 
Published: January 2005

AbstractBenzenetellurinyl trifluoromethanesulfonate in conjunction with acetonitrile readily effected amidotellurinylation reactions with alkynes. Most of the addition reactions proceeded in a trans fashion to form the (E)‐β‐acetamidovinyl phenyl telluroxides. Subsequently, it was found that the prevailing Markovnikov adducts from terminal alkynes immediately isomerized to (Z)‐isomers which were isolated as the corresponding vinyltellurides. On the other hand, the adducts derived from internal alkynes thermally underwent a spontaneous intramolecular cyclization to be transformed eventually into oxazoles.
Studies on organophosphorus compounds 81. A novel synthetic approach to substituted cyclopentane‐1,1‐diylbisphosphonates via Pd(0) catalyzed enyne cyclization
Authors: Li Chaozhong , Yuan Chengye 
Published: January 2005

AbstractIntramolecular enyne cycloisomerization reactions catalyzed by Pd(PPh3)4 gave 4‐substituted 3‐methylenecyclopentane‐1,1‐diylbisphosphonates in good yield.
Stereoselective synthesis of and atropisomerism in 4‐pyridyl‐3‐(1‐pyridinio)‐3,4‐trans‐1,2,3,4‐tetrahydropyridines and their transformation products
Authors: Shestopalov Anatolij M. , Bogomolova Olga P. , Rodinovskaja Ludmila A. , Litvinov Victor P. , Bujnicki Bogdan , Mikol̀ajczyk Marian , Nesterov Vladimir N. , Struchkov Yurij T. 
Published: January 2005

AbstractA series of 2‐oxo‐4‐pyridyl‐3‐(1‐pyridinio)‐5‐cyano‐3,4‐trans‐1,2,3,4‐tetrahydropyridine‐6‐6‐olates were prepared by condensation of pyridinium ylides with α,β‐unsaturated carbonyl compounds or more conveniently by a three‐component condensation of pyridinium ylides, pyridine aldehydes, and ethyl cyanoacetate 3 and/or 6. This analogues of the above tetrahydropyridines were prepared in a similar way starting from suitable substrates. Spectroscopic data revealed that the reaction leads to trans‐isomers around the C3‐C4 bond and is atroposelective. The conformation of and tautomerism in the tetrahydropyridines are discussed in the light of 1H NMR data. The reaction of 5‐cyano‐3‐(3‐methyl‐1‐pyridinio)‐2‐oxo‐4‐(3‐pyridyl)‐1,2,3,4‐tetrahydropyridine‐6‐thiolate 10c with phenacyl bromide was found to give 3‐hydroxy‐5‐oxo‐7‐(3‐pyridyl)‐6‐(3‐methyl‐1‐pyridinio)‐3‐phenyl‐8‐cyano‐6,7‐trans‐2,3,6,7‐tetrahydrothiazol[3,2a]pyridine bromide, the crystal and molecular structure of which has been determined by X‐ray crystallographic analysis.
1‐Aminothiaalkanephosphonic acids and their sulfinyl and sulfonyl derivatives: Synthesis and acidic properties
Authors: Kudzin Zbigniew H. , Andrijewski Grzegorz , Drabowicz Józef 
Published: January 2005

AbstractSeveral 1‐aminothialkanephosphonic acids 2 were synthesized and selectively oxidized to their sulfinyl 3 and sulfonyl 4 derivatives. For the compounds 2, 3, and 4, their dissociation properties were determined potentiometrically.
A mild and efficient synthesis of intermediates for the Pomeranz‐Fritsch reaction
Authors: Katritzky Alan R. , Yang Zhijun , Cundy Darren J. 
Published: January 2005

AbstractReaction of 1‐chloro‐2,2‐dimethoxyethane with sodium azide affords 1‐azido‐2,2‐dimethoxyethane which, upon treatment with triphenylphosphine followed by aromatic aldehydes, alkyl bromides, or isocyanates, gives the corresponding dimethyl α‐arylimino‐, α‐alkylamino‐, and α‐carbodiimido‐acetals, respectively, in good to excellent yields.
Crystal and molecular structure and determination of absolute configuration of two enantimers of methoxycarbonylmethyl carboxymethyl sulfoxide
Authors: Wieczorek Michał W. , Błaszczyk Jarosław , Mikołajczyk Marian , Kiełbasiń;ski Piotr , ŻurawińSki Remigiusz 
Published: January 2005

AbstractCrystal and molecular structures of two enantiomers of methoxycarbonylmethyl carboxymethyl sulfoxide 2 ( 2(−) and 2(+) ) have been determined by X‐ray methods. Crystals of 2 are orthorhombic, space group P212121, Z = 4, with a = 5.1900(4) Å, b = 8.7960(7) Å, and c = 18.489(2) Å in 2(−) and a = 5.1897(7) Å, b = 8.787(1) Å, and c = 18.520(2) Å in 2(+). Structures 2(−) and 2(+) were refined to R factors equal to 0.041 and 0.052, respectively. The absolute configuration at the sulfur atom in enantiomer 2(−) with [α] = −20° (MeOH) is Rs. (In 2(+), where [α] equals + 20° (MeOH), the absolute configuration at S atom is Ss.) In compounds 2(−) and 2(+), a strong intermolecular hydrogen bond O3H3 … O1 occurs.
Cyclization of Ph2Si(NHNHMe)2. I. Reaction with n‐BuLi/Ph2SiCl2 and ring rearrangement
Authors: He Jiliang , Harrod John F. 
Published: January 2005

AbstractReaction of Ph2Si(NHNHMe)2 (1) with n‐BuLi and Ph2SiCl2 in 1 : 2 : 1 ratio afforded 54% of 1,2,4‐triaza‐1‐methyl‐4‐methylamino‐3,3, 5, 5‐tetraphenyl‐3,5‐disilacylopentane (2). In the presence of a catalytic amount of n‐BuLi, 2 is rearranged to two isomers, 1,2,4,5‐tetraaza‐1,4‐dimethyl‐3,3,6,6‐tetraphenyl‐3,6‐disilacyclohexane (3) and 1,2,4,5‐tetraaza‐1,5‐dimethyl‐3,3,6,6‐tetraphenyl‐3,6‐disilacyclohexane (4), with 3 as the major product. The crystal structure of 3 reveals a twist‐boat conformation of the Si2N4 ring [a = 10.691(4) Å, b = 13.178(4) Å, c = 17.812(3) Å, β = 95.11(7)°; monoclinic, P21/n; Z = 4], in which eachN(Me)N(H)unit contains one pyramidal (NH) and one planar (NMe) nitrogen.
The intramolecular sila‐Pummerer cyclization: A new route to sulfur heterocycles
Authors: Still Ian W. J. , Toste F. Dean 
Published: January 2005

AbstractThe generality of the intramolecular cyclization of suitable nucleophilic sites to a S+CH2 center created by a sila‐Pummerer rearrangement has been investigated. Successful nucleophilic sites included the OH group (in alcohols, carboxylic acids, and hydroxylamines) and the NH group (in amines and carbamates): attempts to produce carbon‐based nucleophilic sites were not effective. Successful cyclizations were achieved to produce sulfur heterocycles with 5‐, 6‐, and 7‐membered rings.
Reactions of N‐sulfonyldiarylchalcogenimides with diaryl ditellurides
Authors: Naddaka Vladimir I. , Cherkinskaya Marina L. , Avanesyan Knarik V. 
Published: January 2005

AbstractUnlike the N‐sulfonylsulfimide 1a, which does not react with diaryl ditellurides 2 even at 180°C, the selenimide 1b, and tellurimides 1c,d convert quantitatively compounds 2 to N,N‐bis‐(N′‐p‐tosylimidoarenetellurinyl)‐p‐tosylamides 4a,b in refluxing benzene. The reactivity of N‐sulfonylchalcogenimides 1 increases in the order S < Se < Te. Diaryl telluroxides 6 readily oxidize ditellurides 2 to arenetellurinic anhydrides 5. The mechanisms of these reactions are discussed.
Modified components of RNA. The molecular and crystal structure of 5‐carboxymethylaminomethyl‐2‐thiouridine (S2cmnm5U)
Authors: Wieczorek Michał W. , Bujacz Grzegorz D. , Adamiak Dorota A. , Małkiewicz Andrzej , Nawrot Barbara 
Published: January 2005

AbstractThe structure of the title compound 1 has been determined by X‐ray analysis. The following crystal data were found: orthorhombic, P212121, a = 5.243(2), b = 24.864(4), and c = 37.083(6) Å. Three molecules of the compound with four molecules of water are present in the independent part of the unit cell. The sugar ring puckering is 3E for the molecules A and C and 3T2 for the molecule B. The conformation of the hydroxymethylene group is g+ and g− for B and A, C, respectively. The torsion angles χ for all molecules are in the range of the anti conformation. In the crystal lattice of 1 both the intra‐and intermolecular hydrogen bonding systems occur.
Convenient synthesis of heterocycles by sulfur‐assisted carbonylation at ordinary pressure and temperature
Authors: Mizuno Takumi , Toba Hitoshi , Miyata Toshiyuki , Nishiguchi Ikuzo 
Published: January 2005

AbstractHeterocyclic compounds, including benzimidazolones, naphthimidazolone, benzoxazolones, benzothiazolone, quinazolinone, benzoxazinone, quinazolinedione, and imidazopyridinone were synthesized in good yields by sulfur‐assisted carbonylation of aromatic amines with carbon monoxide (1 atm) at room temperature, with subsequent oxidation using molecular oxygen (1 atm, RT). The present method is characterized as a simple procedure carried out under quite mild conditions.
An unexpected synthesis of thiophene derivatives by thionation of N‐phenylacetylthiobenzamides
Authors: Lai Long‐Li , Reid David H. , Wang Sue‐Lein , Liao Fen‐Ling 
Published: January 2005

AbstractFour thiophene derivatives have been obtained unexpectedly from the reaction of N‐phenylacetyithiobenzamides with P4S10 in boiling carbon disulfide. The structure of one of these was established by X‐ray crystallography.
Synthesis of 1‐(8‐phosphonomethoxy‐3,6‐dioxaoctyl)pyrimidines and purines, a novel series of acyclonucleotide analogues
Authors: Charron Marie , Tse H. L. Allan , Mansour Tarek S. , Knight David J. , O'Sullivan Corrine , Coates Jonathan A. V. 
Published: January 2005

AbstractA convenient synthesis of 1‐(8‐phosphonomethoxy‐3,6‐dioxaoctyl) uracil, cytosine, adenine, and guanine nucleotide analogues 26, 28, 30, and 32 by Mitsunobu coupling of the nucleobases with suitably functionalized alcohol derivative 24 is described. The antiviral activity of this series of compounds against herpes simplex virus (HSV) types 1 and 2 and human cytomegalovirus is reported.
Electrophilic chemistry of the cubic arsaalkyne tetramer (AsCtBu)4: Arsonium ions of ethylation (EtOTf), benzylation (PhCH2OTf), and mono‐ and diprotonation (FSO3H/SO2)
Authors: Laali Kenneth K. , Nixon John F. , Johnson Julian A. 
Published: January 2005

AbstractThe cubic arsaalkyne tetramer 2 reacts at room temperature with ethyl triflate to give the As‐ethylated arsonium salt 4. A similar reaction of 2 with benzyl triflate (generated in situ via PhCH2Cl/AgOTf) gives the As‐benzylated salt 5. Low‐temperature protonation of 2 with FSO3H/SO2 produces a mixture of arsonium ions 6 and 7 resulting from mono‐ and diprotonation. The NMR characteristics of the resulting arsonium ions are discussed and compared with those of the corresponding phosphonium ions derived from the tetraphosphacubane 3. The FAB mass spectrum of 4 and its decomposition products (FAB‐CAD‐MS/MS) are also discussed.