bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complexity of patients with or without infectious disease consultation in tertiary-care hospitals in Germany
Authors: Meyer-Schwickerath C. , Weber C. , Hornuss D. , Rieg S. , Hitzenbichler F. , Hagel S. , Ankert J. , Hennigs A. , Glossmann J. , Jung N. ,   The German,   Clinical Study Group in Infectious Diseases (DESTINi)
Published: January 2024

Abstract
Purpose
Patients seen by infectious disease (ID) specialists are more complex compared to patients treated by other subspecialities according to Tonelli et al. (2018). However, larger studies on the complexity of patients related to the involvement of ID consultation services are missing.

Methods
Data of patients being treated in 2015 and 2019 in four different German university hospitals was retrospectively collected. Data were collected from the hospitals’ software system and included whether the patients received an ID consultation as well as patient clinical complexity level (PCCL), case mix index (CMI) and length of stay (LOS) as a measurement for the patients’ complexity. Furthermore, a comparison of patients with distinct infectious diseases treated with or without an ID consultation was initiated.

Results
In total, 215.915 patients were included in the study, 3% (n = 6311) of those were seen by an ID consultant. Patients receiving ID consultations had a significantly (p < 0.05) higher PCCL (median 4 vs. 0), CMI (median 3,8 vs. 1,1) and deviation of the expected mean LOS (median 7 days vs. 0 days) than patients in the control group. No differences among hospitals or between years were observed. Comparing patients with distinct infectious diseases treated with or without an ID consultation, the differences were confirmed throughout the groups.

Conclusion
Patients receiving ID consultations are highly complex, frequently need further treatment after discharge and have a high economic impact. Thus, ID specialists should be clinically trained in a broad spectrum of diseases and treating these complex patients should be sufficiently remunerated.
Pharmacological Treatment of GHB Withdrawal Syndrome
Authors: Karila Laurent , Angerville Bernard , Benyamina Amine , Billieux Joël 
Published: January 2024

Abstract
Purpose of Review
Gamma-hydroxybutyrate (GHB) is an illicit drug used for many reasons: during music festivals or parties, for self-management of sleep and anxiety, or in combination with other drugs to facilitate chemsex. Most people who use GHB do so occasionally, without harm. However, a minority of users experience dependence or withdrawal symptoms. GHB withdrawal syndrome often has a specific course, with rapid onset and swift progression of severe complications. In this narrative review, we aimed to summarize recent evidence related to the pharmacological treatment of GHB withdrawal syndrome.

Recent Findings
The management of GHB withdrawal syndrome is challenging due to the lack of specific evaluation tools and pharmacological treatment guidelines. From current findings, two pharmacological regimens could be considered for inpatients and outpatients with GHB dependence during detoxification: benzodiazepines and pharmaceutical GHB.

Summary
Few detoxification protocols for GHB or its analogs have been reported in the literature. The main available evidence is based on case studies and uncontrolled open-label studies, which support the efficacy of pharmacological interventions, notably high-dose benzodiazepines and titration and tapering with pharmaceutical GHB, for the management of GHB withdrawal. Barbiturates such as phenobarbital and baclofen might also represent new therapeutic options. Future research should examine these pharmacological interventions with large-scale randomized trials, withdrawal scales, or validated treatment protocols.
Catenaries in Riemannian surfaces
Authors: da Silva Luiz C. B. , López Rafael 
Published: January 2024

AbstractThe concept of catenary has been recently extended to the sphere and the hyperbolic plane by the second author (López, arXiv:2208.13694). In this work, we define catenaries on any Riemannian surface. A catenary on a surface is a critical point of the potential functional, where we calculate the potential with the intrinsic distance to a fixed reference geodesic. Adopting semi-geodesic coordinates around the reference geodesic, we characterize catenaries using their curvature. Finally, after revisiting the space-form catenaries, we consider surfaces of revolution (where a Clairaut relation is established), ruled surfaces, and the Grušin plane.
Dimensionless quantities in discrete element method: powder model parameterization for additive manufacturing
Authors: Girnth Simon , Heitkamp Tim , Wacker Christian , Waldt Nils , Klawitter Günter , Dröder Klaus 
Published: January 2024

AbstractPowder bed-based additive manufacturing processes offer an extended freedom in design and enable the processing of metals, ceramics, and polymers with a high level of relative density. The latter is a prevalent measure of process and component quality, which depends on various input variables. A key point in this context is the condition of powder beds. To enhance comprehension of their particle-level formation and facilitate process optimization, simulations based on the Discrete Element Method are increasingly employed in research. To generate qualitatively as well as quantitatively reliable simulation results, an adaptation of the contact model parameterization is necessary. However, current adaptation methods often require the implementation of models that significantly increase computational effort, therefore limiting their applicability. To counteract this obstacle, a sophisticated formula-based adaptation and evaluation method is presented in this research. Additionally, the developed method enables accelerated parameter determination with limited experimental effort. Thus, it represents an integrative component, which supports further research efforts based on the Discrete Element Method by significantly reducing the parameterization effort. The universal nature of deducting this method also allows its adaptation to similar parameterization problems and its implementation in other fields of research.
Red light mediates the exocytosis of vasodilatory vesicles from cultured endothelial cells: a cellular, and ex vivo murine model
Authors: Weihrauch Dorothee , Keszler Agnes , Broeckel Grant , Aranda Eva , Lindemer Brian , Lohr Nicole L. 
Published: January 2024

AbstractWe have previously established that 670 nm energy induces relaxation of blood vessels via an endothelium derived S-nitrosothiol (RSNO) suggested to be embedded in vesicles. Here, we confirm that red light facilitates the exocytosis of this vasodilator from cultured endothelial cells and increases ex vivo blood vessel diameter. Ex vivo pressurized and pre-constricted facial arteries from C57Bl6/J mice relaxed 14.7% of maximum diameter when immersed in the medium removed from red-light exposed Bovine Aortic Endothelial Cells. In parallel experiments, 0.49 nM RSNO equivalent species was measured in the medium over the irradiated cells vs dark control. Electron microscopy of light exposed endothelium revealed significant increases in the size of the Multi Vesicular Body (MVB), a regulator of exosome trafficking, while RSNO accumulated in the MVBs as detected with immunogold labeling electron microscopy (1.8-fold of control). Moreover, red light enhanced the presence of F-actin related stress fibers (necessary for exocytosis), and the endothelial specific marker VE-cadherin levels suggesting an endothelial origin of the extracellular vesicles. Flow cytometry coupled with DAF staining, an indirect sensor of nitric oxide (NO), indicated significant amounts of NO within the extracellular vesicles (1.4-fold increase relative to dark control). Therefore, we further define the mechanism on the 670 nm light mediated traffic of endothelial vasodilatory vesicles and plan to leverage this insight into the delivery of red-light therapies.
Graphical abstract
Ecological features of trace elements tolerant microbes isolated from sewage sludge of urban wastewater treatment plant
Authors: Perelomov L. , Rajput V. D. , Gertsen M. , Sizova O. , Perelomova I. , Kozmenko S. , Minkina T. , Atroshchenko Y. 
Published: January 2024

AbstractWorldwide wastewater treatment plants generate enormous amounts of sewage sludge, and their further disposal depends on the treatment technologies applied and spontaneously occurring microbiological processes. From different ages urban sewage sludge, 12 strains of bacteria with simultaneous tolerance to two or more trace elements: Co, Ni, Cu, Zn, Cd and Pb at concentration of 3-5 mmol were isolated and identified by PCR of target genes and Sanger sequencing methods. The isloated metal(loids) tolerant strains belong to the species, i.e., Serratia fonticola, Rhodococcus qingshengii, Pseudomonas fragi, Pseudomonas extremaustralis, Pseudomonas cedrina, Stenotrophomonas maltophilia, Serratia liquefaciens and Citrobacter freundii. The ecological features of the isolated strains were studied. The optimal growth temperatures for most strains was 15–30°C at pH range of 5–9, although some strains grew at 7°C (Pseudomonas fragi SS0-4, Serratia fonticola SS0-9 and Serratia fonticola SS12-11). Satisfactory growth of two strains (Serratia fonticola SS0-1and Citrobacter freundii SS60-12) was noted in an acidic medium at pH 4. Most of the strains grew in the NaCl concentration range of 1–5%. The isolated bacteria resistant to high concentrations of trace elements can be used for the effective mineralization of sewage sludge and for the decontamination of wastewater.
Computational fluid dynamic simulation of packed bed drying process: impact of particle properties, drying conditions, and lateral edge heating modes on drying kinetics
Authors: Tran Thi Thu Hang , Le Kieu Hiep 
Published: January 2024

AbstractIn this work, a two-dimensional computational fluid dynamic (CFD) model is developed to describe the drying process of a packed bed made of spherical particles. The volumetrical evaporation rate inside the bed is computed from the pressure difference between the particle surface and the airflow. By using the thermal equilibrium assumption, the heat conservation equation is derived. The CFD model is solved in the COMSOL Multiphysics environment. The obtained results indicate remarkable maldistributions of temperature and moisture content. These maldistributions can be explained by the impact of lateral edges on thermo-hydraulic behavior. Additionally, the impact of particle diameter, air velocity, and bed width on the spatial-temporal moisture content and temperature distribution is investigated. It shows that the CFD model can be simplified to the receding front drying model for a bed made of small particles. Furthermore, by changing the thermal boundary conditions at the lateral edges, the influence of the heating mode at the lateral edges on the drying behavior is explored. The results indicate that contact heating at the bed wall can help to accelerate the drying process significantly.
Fast elimination of emerging contaminates in complicated water environment medium over the resource conversion product of chicken manure biochar triggered by peroxymonosulfate
Authors: Sun Yingtao , Gu Yuting , Li Meiyi , Wang Hongqiang , Hu Chun , Lyu Lai 
Published: January 2024

AbstractAn innovative strategy for synthesizing novel dual-reaction-center (DRC) catalysts from chicken manure (CM) biochar to purify wastewater that contained emerging contaminants (ECs) is proposed to synchronously address the release of ECs and improper disposal of livestock manure. A series of characterization techniques reveal the formation of a special C-O-Ca bond bridge (cation-π) structure on resourcelized CM nanosheets (RCM NSs). RCM NSs exhibit distinct selectivity and anti-interference capability for various ECs removal in complex matrices, and the water purification system remains stable after 1735 hours (equivalent to 3470 cycles) of operation. Density Functional Tomography (DFT) calculations reveal that trace of peroxymonosulfate as an inducer initiates the continuous donation of electrons from electron-rich ECs and the C-O-Ca bond bridges provide a favorable pathway for electron transfer, which facilitates the electron capture effect of dissolved oxygen in the system. This study provides a novel strategy to convert livestock manure into DRC-catalysts for developing energy-saving and high-efficiency environmental remediation technologies.
Graphical Abstract
Microplastic pollution as an environmental risk exacerbating the greenhouse effect and climate change: a review
Authors: Li Kui , Du Linsen , Qin Chanyuan , Bolan Nanthi , Wang Hailong , Wang Hua 
Published: January 2024

AbstractMicroplastics are polymer-based materials with carbon as their main framework. During degradation, they release greenhouse gases such as carbon dioxide and methane. Additionally, environmental microplastics can enter plant tissues, triggering oxidative stress in plant cells, adversely affecting photosynthesis, metabolism, gene expression, and other growth parameters. This reduction in plant efficiency in sequestering and utilizing atmospheric carbon dioxide indirectly impacts global carbon cycling, exacerbating the global greenhouse effect. Furthermore, environmental microplastics significantly alter soil structure and the composition of microbial communities, affecting the emissions of greenhouse gases such as carbon dioxide, methane, and nitrous oxide, thus indirectly promoting greenhouse gas emissions. Increasing research suggests a mutual reinforcement between microplastic pollution and global climate warming, where microplastic pollution exacerbates global climate warming, and the rise in global average temperature leads to the resuspension of microplastics in sediments, intensifying microplastic pollution in the environment. This article primarily focuses on the impacts of environmental microplastic pollution on different ecosystems and the relationship between microplastic pollution and global climate warming. It summarizes the effects of microplastic pollution on greenhouse gas emissions in marine, terrestrial, and atmospheric ecosystems, as well as the mechanisms by which microplastics and climate change affect ecosystem services. By delving into the intricate connection between microplastic pollution and greenhouse gas emissions, this paper aims to raise awareness of the climate change caused by microplastic pollution and calls for further research on the impacts of microplastics on ecosystems and global climate change, with the ultimate goal of protecting ecosystems and human health.
Graphical Abstract
Unveiling global research trends in construction productivity: a scientometric analysis of twenty-first century research
Authors: Van Tam Nguyen 
Published: January 2024

AbstractConstruction productivity research has exploded in the twenty-first century, captivating scholars worldwide. To navigate this burgeoning field, this study utilizes a scientometric analysis approach to identify and evaluate 710 academic articles, examining geographical publication patterns, author contributions, leading journals, keyword co-occurrences, and key findings from previous studies. The results reveal that the United States, Canada, and Australia are the top contributors in terms of publication output. The Journal of Construction Engineering and Management, Automation in Construction, and Construction Management & Economics emerged as leading journals. Keyword analysis finds “productivity,” “construction industry,” and “project management” to be the most prevalent. Notably, research relies on empirical methods like questionnaires and utilizes popular measures such as relative importance index, factor analysis, and regression analysis. Additionally, smart construction and sustainable cities appear as promising paradigms for achieving sustainable productivity. Furthermore, prior studies advocate for workforce upskilling, enhanced motivation, work environment improvements, strengthened site management, and embraced technological advancements to boost construction productivity. This paper enriches the existing body of knowledge by mapping the global research landscape on construction productivity, uncovering emerging trends, identifying influential contributors, and highlighting promising areas for future research. In practical terms, it provides construction practitioners with valuable insights into emerging technologies and promising management approaches that can enhance productivity and optimize construction processes.
Identification of distinct roses suitable for future breeding by phenotypic and genotypic evaluations of 192 rose germplasms
Authors: Guan Huilin , Huang Bingyao , Yan Xinyue , Zhao Jiaxing , Yang Shaozong , Wu Quanshu , Bao Manzhu , Bendahmane Mohammed , Fu Xiaopeng 
Published: January 2024

AbstractRose (Rosa) is a prominent ornamental plant that holds substantial economic and social significance. Roses originating from different regions exhibit intricate phenotypic and genetic characteristics, but the majority of rose genetic resources are poorly characterized. In this study, 192 genotypes of the genus Rosa were examined using 33 phenotypic traits and 10 pairs of SSR markers. Compared to wild species, both old garden and modern roses exhibited a significant level of diversity, with flower color having the highest degree of diversity and style morphology having the lowest degree of diversity. This phenomenon may be attributed to the limited utilization of wild roses due to their simpler ornamental traits and the frequent phenotypic and molecular infiltration between old garden roses and modern roses. Following a inaugural comprehensive evaluation employing principal component analysis, R. chinensis ‘Zihongxiang’, R. hybrida ‘Burgundy Iceberg’, R. hybrida ‘Conrad F. Meyer’, R. rugosa ‘Gaohong’ and R. floribunda ‘Sheherazad’ were selected as core germplasm resources for future breeding. Moreover, three tetraploid roses, namely R. hybrida ‘Midnight Blue’, R. floribunda ‘Sheherazad’, and R. hybrida ‘Couture Rose Tilia’, with significant differences in both phenotypic and molecular profiles were selected and reciprocally intercrossed. Ultimately, two populations were obtained exhibiting significant variation in flower size, annual stem color, stem pickle density, and leaf number. Furthermore, our results indicated that the traits of flower diameter, flower height, petal width, and petal number may potentially be controlled by two major-effect loci. In conclusion, this study provides novel insights into the evolutionary patterns of Rosa germplasm resources. It paves the way for identifying core genotypes that carry distinct ornamental characteristics and possess immense value for breeding novel varieties in the future.
Involvement of citrus shoots in response and tolerance to abiotic stress
Authors: Vives-Peris Vicente , Pérez-Clemente Rosa M. , Gómez-Cadenas Aurelio , López-Climent María F. 
Published: January 2024

AbstractTraditionally, the root system has been regarded as the primary component influencing citrus tolerance. Aerial tissues also play a crucial role in abiotic stress tolerance, as they are responsible for vital physiological processes, such as photosynthesis and transpiration. In addition, these tissues are directly exposed to various stress conditions, including extreme temperatures (heat and cold), high light irradiation, and ultraviolet (UV) exposure. In the current climate change scenario, optimizing both citrus rootstocks and grafted scions is crucial to ensure fruit quality and crop yield. Various approaches have been used to investigate the significance of aerial tissues, including in vitro systems, isolated aerial tissue growth, reciprocal grafting, and girdling. This review highlights recent research on the role of aerial tissues in citrus plants under various abiotic stress conditions. Studying and optimizing the genotypes used as scions in grafted citrus plants under abiotic stress conditions is crucial and may contribute to the development of new crop management strategies and breeding programs. Furthermore, this knowledge could be extended to other crops, enabling the development of more resilient and productive agricultural systems.
Weathering alteration in the Antarctic environment as seen in the Miller Range (MIL) 090030 Martian meteorite
Authors: Coloma Leire , Aramendia Julene , Huidobro Jennifer , Población Iratxe , García-Florentino Cristina , Castro Kepa , Arana Gorka , Madariaga Juan Manuel 
Published: January 2024

AbstractThe analysis of Martian meteorites is a key research to understand the mineralogical composition of Mars. However, they suffer different types of alteration due to the environment where they fall on Earth. These differences should be identified in order to characterize correctly the original Martian compounds. Most of the meteorites found on Earth are collected in Antarctica where the environmental conditions are such that, in general and based on many previous investigations, produce fewer alterations compared with other terrestrial environments such as hot deserts. In this study, the weathering alterations of minerals from the MIL 090030 Martian Nakhlite found in Antarctica were analyzed to determine which minerals are formed by Antarctic environmental conditions. It was confirmed that the south-polar region environment can contaminate Martian meteorites and, in this study, several minerals like halite, nitratine and niter, were detected as weathering alteration products that have not been referenced in the literature before.
Repentance, Atonement, and Aquinas
Authors: Schmidt Taylor Greggory 
Published: January 2024

AbstractRepentance is central to the message of Christianity. Yet, repentance has received little analysis in recent scholarship despite being emphasized by the church fathers. In particular, there has been minimal effort to understand the necessity of repentance in light of Christ’s atoning work. With this as the background, I explore fundamental questions such as repentance’s definition, scope, and role in salvation history. Furthermore, I attempt to more precisely outline repentance’s role in Christ’s salvific work. Underpinning the project is my view that repentance should be understood as metanoia or transformation. This transformation of repentance is ordered toward divine metanoia – participation in Christ. In developing repentance, I put forward a synthesis of Thomas Aquinas’s framework of penance and John McLeod Campbell’s account of Christ’s vicarious repentance. Through this synthesis, I attempt to make sense of the relationship between repentance and atonement. I finish by suggesting that it would be appropriate to conclude that Thomas would endorse a vicarious repentance account of the atonement and hint at how it might fit into broader soteriologies.
Loser Takes All: Graham Greene’s Theological Puzzle Box
Authors: Comerford Peter J. 
Published: January 2024

AbstractGraham Greene’s novella Loser Takes All has been unfairly ignored in the critical literature. Rather than the mere frivolity it is taken to be, it is a humorous examination of some serious theological issues. By means of an inversion of Pascal’s Great Wager, Greene makes the case that attempts to rationalize the mystery that is the object of our faith will cheapen and diminish that faith. In the course of so doing, he alludes to and has fun with his earlier works, particularly Brighton Rock, and critiques the inversion of the Wager by Albert Camus. He shows the influence of Miguel de Unamuno, who years later would influence Greene’s Monsignor Quixote. Greene also invokes a poem by Charles Baudelaire, which Greene has quoted in many works, that the possibility of damnation adds meaning to life, though it may drift into what von Balthasar called Greene’s indulgence of the mystique of sin.