bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-cultural adaptation of educational design patterns at scale
Authors: Vallis Carmen Jane , Nguyen Huyen Thi , Norman Adrian 
Published: February 2024

PurposeEducational design patterns offer practical strategies that can be shared and adapted to address problems in teaching and learning. This article explores how educational design patterns for connected learning at scale at an Australian university may be adapted to a Vietnamese higher education context.Design/methodology/approach12 educational design patterns that address the challenges of active learning and large teaching team management are discussed. The authors then critically reflect on their cross-cultural adaptation for the higher education context, from an Australian to a Vietnamese university.FindingsTransitioning from passive to active learning strategies and effectively leading large teaching teams present similar challenges across our contexts. Educational design patterns, when dynamically adapted, may assist educators to teach skills that are critical for work and the future. Higher education institutions globally could enhance their practices by incorporating international best practice approaches to educational design.Practical implicationsThe Connected Learning at Scale (CLaS) educational design patterns explored in this article offer solution-oriented strategies that promote a more active learning experience. This paper identifies adaptations for educators, especially those in Vietnamese higher education that respect traditional structures, cultural nuances and resource limitations in implementation.Originality/valueWhilst educational design patterns are well-researched in the Western contexts, few studies analyse design patterns in an Asian, and in particular the Vietnamese context. More research is needed in the cross-cultural adaptation of educational design patterns that joins practice and theory.
Perceived climate of Cha-xu and trust on knowledge sharing: a moderated mediation model
Authors: Xia Fangfang , Wang Changfeng , Sun Rui , Qi Mingyue 
Published: February 2024

Purpose
This study aims to identify an antecedent that hinders knowledge sharing, namely, the perceived climate of Cha-xu. Based on the social exchange perspective, the authors propose a theoretical model that links the perceived climate of Cha-xu to employee knowledge sharing. This model focuses on the mediating role of two types of trust (vertical and horizontal trust) and the moderating role of task interdependence in influencing the mediation.

Design/methodology/approach
Using a sample of 509 Chinese employees, this study carried out a survey on an online platform. This study developed a structural equation model and tested the moderated mediation hypothesis by using Mplus 8.0.

Findings
The results showed that two types of trust act as mediators in the relationship between the perceived climate of Cha-xu and knowledge-sharing processes. The mediating effect of horizontal trust is stronger. Most significantly, findings show that this mediated relationship is contingent on the level of task interdependence.

Originality/value
This paper provides evidence for distinguishing vertical trust and horizontal trust in the field of knowledge management. From a managerial perspective, this study identifies traditional cultural factors for hindering knowledge-sharing processes within Chinese organizations.
Shifts from an extensive to an intensive root nutrient‐acquisition mode with stand development of three Pinus species
Authors: Wang Guangru , Lin Guigang , Zhang Yansong , Zheng Linlin , Zeng De‐Hui , Lambers Hans 
Published: February 2024

Abstract

Plant roots employ diverse strategies to acquire soil nutrients, including direct nutrient uptake through absorptive fine roots and root hairs, scavenging nutrients by forming symbioses with mycorrhizal fungi, and mining nutrients by releasing root exudates. However, whether these three strategies are differently coordinated among phylogenetically closely related tree species and how this coordination shifts with stand development remains largely unclear.

To fill these knowledge gaps, we measured 13 root morphological, architectural, physiological and mycorrhizal traits tightly related to nutrient‐acquisition of three Pinus species (P. sylvestris var. mongolica, P. densiflora and P. tabuliformis) at young (20‐year‐old) and mature (50‐year‐old) stages planted in nutrient‐impoverished sandy soils, in Northeast China.

We found that young trees had thinner absorptive fine roots and a higher specific root length than mature trees across three Pinus species, indicating that roots become morphologically less efficient in ‘do it yourself’ scavenging nutrients during stand development. Moreover, young stands had greater root length density and root area index, and mature stands had faster root‐exudation rates, suggesting that young stands rely more on expanding soil volumes to scavenge nutrients and mature stands depend more on root exudation to ‘mine’ nutrients. The three Pinus species exhibited different nutrient‐acquisition strategies at the mature stage; P. densiflora had higher root length density and root area index, and the other two Pinus species had greater ectomycorrhizal colonization rates.

Synthesis. Our findings highlight that phylogenetically closely related tree species may exhibit different nutrient‐acquisition strategies and suggest a shift from an extensive nutrient‐acquisition mode depending more on absorptive fine roots to an intensive nutrient‐acquisition mode relying more on root exudation during stand development.
Caesarean delivery: Global perspective on unwanted effects
Authors: Lumbiganon Pisake , Tungtang Paradee , Jampathong Nampet 
Published: February 2024

Linked article: This is a mini commentary on Al Khalaf et al., pp. 1054‐1061 in this issue. To view this article visit https://doi.org/10.1111/1471‐0528.17760.
Synergic kinetic and physiological control to improve the efficiency of Komagataella phaffii recombinant protein production bioprocesses
Authors: Sales‐Vallverdú Albert , Gasset Arnau , Requena‐Moreno Guillermo , Valero Francisco , Montesinos‐Seguí José Luis , Garcia‐Ortega Xavier 
Published: February 2024

AbstractThe yeast Komagataella phaffii (Pichia pastoris) is currently considered a versatile and highly efficient host for recombinant protein production (RPP). Interestingly, the regulated application of specific stress factors as part of bioprocess engineering strategies has proven potential for increasing the production of recombinant products. This study aims to evaluate the impact of controlled oxygen‐limiting conditions on the performance of K. phaffii bioprocesses for RPP in combination with the specific growth rate (μ) in fed‐batch cultivations. In this work, Candida rugosa lipase 1 (Crl1) production, regulated by the constitutive GAP promoter, growing at different nominal μ (0.030, 0.065, 0.100 and 0.120 h−1) under both normoxic and hypoxic conditions in carbon‐limiting fed‐batch cultures is analysed. Hypoxic fermentations were controlled at a target respiratory quotient (RQ) of 1.4, with excellent performance, using an innovative automated control based on the stirring rate as the manipulated variable developed during this study. The results conclude that oxygen limitation positively affects bioprocess efficiency under all growing conditions compared. The shift from respiratory to respiro‐fermentative metabolism increases bioprocess productivity by up to twofold for the specific growth rates evaluated. Moreover, the specific product generation rate (qp) increases linearly with μ, regardless of oxygen availability. Furthermore, this hypoxic boosting effect was also observed in the production of Candida antarctica lipase B (CalB) and pro‐Rhizopus oryzae lipase (proRol), thus proving the synergic effect of kinetic and physiological stress control. Finally, the Crl1 production scale‐up was conducted successfully, confirming the strategy's scalability and the robustness of the results obtained at the bench‐scale level.
Indigenous populations of the Pacific and American West
Authors: La Croix Sumner , Maxwell‐Stewart Hamish 
Published: February 2024

AbstractThis special issue of the Asia Pacific Economic History Review explores the impact of colonisation on Indigenous populations across the Pacific and American West from the late eighteenth to the early twentieth century. Three of the contributing articles examine ways of modelling Indigeous populations at point of contact and the scale and pace of subsequent declines. A further two explore the problematics of counting violent deaths on the frontier and reconstructing the factors motivating settler aggression. The last article examines the impact of colonisation on sex ratios and the implications of this for marriage rates between and within different ethnicities.
The neurobiological mechanisms and therapeutic prospect of extracellular ATP in depression
Authors: Wang Kaixin , Huang Shiqian , Fu Daan , Yang Xinxin , Ma Lulin , Zhang Tianhao , Zhao Wenjing , Deng Daling , Ding Yuanyuan , Zhang Yanyan , Huang Li , Chen Xiangdong 
Published: February 2024

AbstractBackgroundDepression is a prevalent psychiatric disorder with high long‐term morbidities, recurrences, and mortalities. Despite extensive research efforts spanning decades, the cellular and molecular mechanisms of depression remain largely unknown. What's more, about one third of patients do not have effective anti‐depressant therapies, so there is an urgent need to uncover more mechanisms to guide the development of novel therapeutic strategies. Adenosine triphosphate (ATP) plays an important role in maintaining ion gradients essential for neuronal activities, as well as in the transport and release of neurotransmitters. Additionally, ATP could also participate in signaling pathways following the activation of postsynaptic receptors. By searching the website PubMed for articles about “ATP and depression” especially focusing on the role of extracellular ATP (eATP) in depression in the last 5 years, we found that numerous studies have implied that the insufficient ATP release from astrocytes could lead to depression and exogenous supply of eATP or endogenously stimulating the release of ATP from astrocytes could alleviate depression, highlighting the potential therapeutic role of eATP in alleviating depression.AimCurrently, there are few reviews discussing the relationship between eATP and depression. Therefore, the aim of our review is to conclude the role of eATP in depression, especially focusing on the evidence and mechanisms of eATP in alleviating depression.ConclusionWe will provide insights into the prospects of leveraging eATP as a novel avenue for the treatment of depression.
Cognitive domains affected post‐COVID‐19; a systematic review and meta‐analysis
Authors: Fanshawe Jack B. , Sargent Brendan F. , Badenoch James B. , Saini Aman , Watson Cameron J. , Pokrovskaya Aleksandra , Aniwattanapong Daruj , Conti Isabella , Nye Charles , Burchill Ella , Hussain Zain U. , Said Khanafi , Kuhoga Elinda , Tharmaratnam Kukatharmini , Pendered Sophie , Mbwele Bernard , Taquet Maxime , Wood Greta K. , Rogers Jonathan P. , Hampshire Adam , Carson Alan , David Anthony S. , Michael Benedict D. , Nicholson Timothy R. , Paddick Stella‐Maria , Leek Charles E. 
Published: February 2024

AbstractBackground and purposeThis review aims to characterize the pattern of post‐COVID‐19 cognitive impairment, allowing better prediction of impact on daily function to inform clinical management and rehabilitation.MethodsA systematic review and meta‐analysis of neurocognitive sequelae following COVID‐19 was conducted, following PRISMA‐S guidelines. Studies were included if they reported domain‐specific cognitive assessment in patients with COVID‐19 at >4 weeks post‐infection. Studies were deemed high‐quality if they had >40 participants, utilized healthy controls, had low attrition rates and mitigated for confounders.ResultsFive of the seven primary Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) cognitive domains were assessed by enough high‐quality studies to facilitate meta‐analysis. Medium effect sizes indicating impairment in patients post‐COVID‐19 versus controls were seen across executive function (standardised mean difference (SMD) −0.45), learning and memory (SMD −0.55), complex attention (SMD −0.54) and language (SMD −0.54), with perceptual motor function appearing to be impacted to a greater degree (SMD −0.70). A narrative synthesis of the 56 low‐quality studies also suggested no obvious pattern of impairment.ConclusionsThis review found moderate impairments across multiple domains of cognition in patients post‐COVID‐19, with no specific pattern. The reported literature was significantly heterogeneous, with a wide variety of cognitive tasks, small sample sizes and disparate initial disease severities limiting interpretability. The finding of consistent impairment across a range of cognitive tasks suggests broad, as opposed to domain‐specific, brain dysfunction. Future studies should utilize a harmonized test battery to facilitate inter‐study comparisons, whilst also accounting for the interactions between COVID‐19, neurological sequelae and mental health, the interplay between which might explain cognitive impairment.
Prevalence and clinical profiles of anti‐myelin‐associated glycoprotein neuropathy in Japan: A nationwide survey study of 133 patients
Authors: Aotsuka Yuya , Misawa Sonoko , Suichi Tomoki , Shibuya Kazumoto , Nakamura Keigo , Kano Hiroki , Otani Ryo , Morooka Marie , Ogushi Moeko , Nagashima Kengo , Sato Yasunori , Kuriyama Nagato , Kuwabara Satoshi 
Published: February 2024

AbstractBackground and purposeThe aim of this study was to determine the prevalence of anti‐myelin‐associated glycoprotein (MAG) neuropathy and the current status of such patients in Japan.MethodsWe conducted a nationwide survey in 2021 using established epidemiological methods. Questionnaires were sent to all neurology and pediatric neurology departments throughout Japan to identify patients with anti‐MAG neuropathy. An initial questionnaire was used to determine the number of patients, with a second one used to collect detailed clinical information.ResultsThe estimated number of patients with anti‐MAG neuropathy was 353, with a prevalence of 0.28 per 100,000 and an incidence of 0.05 per 100,000. The detailed clinical profiles of 133 patients were available. The median (range) age of onset was 67 (30–87) years, with a prominent peak in the age range 66–70 years, and the male‐to‐female ratio was 3.6. Most patients had distal sensory‐predominant polyneuropathy, and neuropathic pain (50%), or sensory ataxia (42%), while 18% had Waldenström's macroglobulinemia or multiple myeloma. Intravenous immunoglobulin was the most frequently used treatment (65%), but the response rate was <50%, whereas rituximab was given in 32% of patients, and 64% of these showed improvement. At the last visit, 27% of patients could not walk independently.ConclusionsThis study on anti‐MAG neuropathy provides updated insights into the epidemiology of this disease, clinical profiles, and treatment approaches in Japan. Rituximab therapy, used for only one‐third of the patients, demonstrated efficacy. During the final visit, a quarter of the patients were unable to walk independently. Further studies are warranted to determine the optimal management of this rare and intractable disorder.
Intraluminal administration of a carboxymethyl‐starch powder for bladder haemorrhage treatment in two adult horses
Authors: Memoli Giulia , Fontana Lucia , Basano Ilaria , Pallante Marcello , Bertuglia Andrea , Bullone Michela 
Published: February 2024

SummaryInternal bleeding and mucosal bleeding in hollow organs are uncommon conditions in equine medicine and endoscopy. Most of the time, they respond to treatment of the underlying primary condition. However, there are cases in which a rapid and effective control of blood loss is required and the animal is not suited for surgery or general anaesthesia. We report two cases referred to our Veterinary Teaching Hospital with signs of urinary disease and bladder haemorrhage identified by cystoscopy which were successfully managed with topical application of a haemostatic carboxymethyl‐starch powder. The product was applied directly on the bleeding mucosa after bladder emptying either under endoscopic guidance or blindly, through a urinary catheter. The application of the haemostatic powder appears to be easy to perform, safe and helpful in controlling mucosal bleeding in hollow organs in a short time, with no adverse reactions noticed. This approach should be considered in cases where mucosal bleeding can be identified by endoscopy and a prompt control of blood loss is required, also in the field.
Climate regulation processes are linked to the functional composition of plant communities in European forests, shrublands, and grasslands
Authors: Kambach Stephan , Attorre Fabio , Axmanová Irena , Bergamini Ariel , Biurrun Idoia , Bonari Gianmaria , Carranza Maria Laura , Chiarucci Alessandro , Chytrý Milan , Dengler Jürgen , Garbolino Emmanuel , Golub Valentin , Hickler Thomas , Jandt Ute , Jansen Jan , Jiménez‐Alfaro Borja , Karger Dirk Nikolaus , Lososová Zdeňka , Rašomavičius Valerijus , Rūsiņa Solvita , Sieber Petra , Stanisci Angela , Thuiller Wilfried , Welk Erik , Zimmermann Niklaus E. , Bruelheide Helge 
Published: February 2024

AbstractTerrestrial ecosystems affect climate by reflecting solar irradiation, evaporative cooling, and carbon sequestration. Yet very little is known about how plant traits affect climate regulation processes (CRPs) in different habitat types. Here, we used linear and random forest models to relate the community‐weighted mean and variance values of 19 plant traits (summarized into eight trait axes) to the climate‐adjusted proportion of reflected solar irradiation, evapotranspiration, and net primary productivity across 36,630 grid cells at the European extent, classified into 10 types of forest, shrubland, and grassland habitats. We found that these trait axes were more tightly linked to log evapotranspiration (with an average of 6.2% explained variation) and the proportion of reflected solar irradiation (6.1%) than to net primary productivity (4.9%). The highest variation in CRPs was explained in forest and temperate shrubland habitats. Yet, the strength and direction of these relationships were strongly habitat‐dependent. We conclude that any spatial upscaling of the effects of plant communities on CRPs must consider the relative contribution of different habitat types.
Calcium hydroxide‐loaded nanoparticles dispersed in thermosensitive gel as a novel intracanal medicament
Authors: Roig Xavier , Halbaut Lyda , Elmsmari Firas , Pareja Rubén , Arrien Aizea , Duran‐Sindreu Fernando , Delgado Luis María , Espina Marta , García María Luisa , Sánchez José Antonio González , Sánchez‐López Elena 
Published: February 2024

AbstractAimDesign, produce and assess the viability of a novel nanotechnological antibacterial thermo‐sensible intracanal medicament This involves encapsulating calcium hydroxide (Ca(OH)2) within polylactic‐co‐glycolic acid (PLGA) nanoparticles (NPs) and dispersing them in a thermosensitive gel (Ca(OH)2‐NPs‐gel). In addition, perform in vitro and ex vivo assessments to evaluate tissue irritation and penetration capacity into dentinal tubules in comparison to free Ca(OH)2.MethodologyReproducibility of Ca(OH)₂‐NPs was confirmed by obtaining the average size of the NPs, their polydispersity index, zeta potential and entrapment efficiency. Moreover, rheological studies of Ca(OH)2‐NPs‐gel were carried out with a rheometer, studying the oscillatory stress sweep, the mean viscosity value, frequency and temperature sweeps. Tolerance was assessed using the membrane of an embryonated chicken egg. In vitro Ca(OH)2 release was studied by direct dialysis in an aqueous media monitoring the amount of Ca(OH)2 released. Six extracted human teeth were used to study the depth of penetration of fluorescently labelled Ca(OH)2‐NPs‐gel into the dentinal tubules and significant differences against free Ca(OH)2 were calculated using one‐way anova.ResultsCa(OH)2‐NPs‐gel demonstrated to be highly reproducible with an average size below 200 nm, a homogeneous NPs population, negative surface charge and high entrapment efficiency. The analysis of the thermosensitive gel allowed us to determine its rheological characteristics, showing that at 10°C gels owned a fluid‐like behaviour meanwhile at 37°C they owned an elastic‐like behaviour. Ca(OH)2‐NPs‐gel showed a prolonged drug release and the depth of penetration inside the dentinal tubules increased in the most apical areas. In addition, it was found that this drug did not produce irritation when applied to tissues such as eggs' chorialantoidonic membrane.ConclusionCalcium hydroxide‐loaded PLGA NPs dispersed in a thermosensitive gel may constitute a suitable alternative as an intracanal antibacterial medicament.
A quasi‐31‐vibrator method for the characterization of piezoelectric full matrix parameters using a single sample
Authors: Huo Da , Wang Biao , Sun Changqing , Zhang Rui , Qi Xudong 
Published: February 2024

AbstractThe full matrix parameters of a piezoelectric material are crucial for designing and evaluating piezoelectric devices. However, due to their inverse problematic nature, commonly used single‐sample characterization methods heavily depend on the accuracy of initial values and mode matching. In this paper, we propose a quasi‐31‐vibrator method to directly evaluate these parameters by designing the sample geometry and establishing the relationship equation between the parameters. This approach completely bypasses the need for characteristic spectrum simulation and mode identification processes. Subsequently, we tested the full matrix parameters of PZT‐5H ceramics and compared the simulated impedance spectra with the measured ones. The presence of well‐fitting spectra validates the feasibility of the method. This method will contribute to characterize the parameters of new piezoelectric materials and advance the intelligent implementation of measuring full matrix parameters.