bluuebunny/crossref_metadata_2025_split huggingface dataset:
Enhanced knowledge inversed attitude of oral cancer risk habit associated with sociocultural: A quantitative and qualitative pilot study
Authors: Nathaniel Fransiskus Arnold , Amtha Rahmi , Gunardi Indrayadi , Hartanto Firstine Kelsi , Sari Elizabeth Fitriana 
Published: October 2023

Abstract

Aim:
In 2023, the global incidence of oral cancer reached 54,540 new cases, with risk factors including smoking (S), alcohol consumption (A), and betel quid chewing (BQC). The knowledge and attitudes about these risk factors impact this practice, particularly in communities that follow local traditions. The aim of this study was to determine the level of knowledge and attitude regarding risk factors for oral cancer on Flores Island, East Indonesia.

Materials and Methods:
This was an analytical observational study with a cross-sectional design using quantitative and qualitative approaches. Structured questionnaires and focus group discussions (FGDs) were conducted with the community, local government, and dentists to obtain data; quantitative analysis was performed using regression; and qualitative analysis was performed using themes.

Results:
Of 542 participants (men 66.42 %; women 33.57 %), 64.4% had a high level of knowledge and a low level of attitude for S = 62.5%, A = 66.7%, and BQC = 50.0%. There was a correlation between knowledge and attitudes about S (P = 0.009) and BQC (P = 0.011). The FGDs yielded 14 subjects (five men and nine women) with three themes of knowledge (betel nut ingredients, causes of cancer, and impacts of habits) and three themes of attitude (type of habit, desire to stop, and oral cancer prevention programs). On the basis of FGDs, most of the subjects already knew the causes of oral cancer, but the desire to stop and prevent oral cancer was difficult.

Conclusion:
The population on Flores Island has a high level of knowledge but a low level of attitude. Nevertheless, it is difficult to minimize or eliminate oral cancer-risk behaviors due to their cultural and socioeconomic conditions.
Family Factors of COVID-19 Vaccine Hesitancy in a Rural Primary Care Environment in Eastern Nigeria: A Cross-sectional Study
Authors: Iloh Gabriel Uche , Chukwuonye Miracle Erinma 
Published: October 2023

Background:
COVID-19 vaccine hesitancy (VH) is a context-specific phenomenon that varies across families around the world. Although factors that are responsible for VH are myriads and differ in times, places, persons, and types of vaccine, family factors may contribute to the variability with the pattern of VH, especially in sociocentric family setting. The aim of the study was to determine family sociomedical factors associated with COVID-19 VH and reasons for VH in a cross-section of adults in rural Nigeria.

Materials and Methods:
A cross-sectional study was carried out from March to April 2021 on 400 adults in eastern Nigeria. Data were collected using a structured, pretested, and researcher-administered questionnaire which elicited information on family factors and reasons for COVID-19 VH.

Results:
The study participants were aged 18–86 with a mean age of 51 ± 14.2 years. There were 227 (56.8%) females. Three hundred and twelve (78.0%) of the study participants were COVID-19 vaccine hesitant. The most common reason for VH was safety of COVID-19 vaccines (100.0%). Family factors associated with VH were young age <50 years (P = 0.002), family nonbelief in COVID-19 infection (P < 0.00001), and family communication on COVID-19 vaccines (P < 0.00026). The independent predictors of VH were age < 50 years (odds ratio [OR] = 2.461; 95%CI, 1.043–5.260; P = 0.010), family nonbelief in COVID-19 infection (OR = 3.752; 95%CI, 1.770–5.011; P = 0.003), and family communication on COVID-19 infection (OR = 2.624; 95%CI, 1.026–7.900; P = 0.029).

Conclusion:
This study has shown the pattern of VH, with the most common reason for VH being safety of COVID-19 vaccines. Independent predictors of VH were age <50 years, family nonbelief in COVID-19 infection, and family communication on COVID-19 vaccines. Widespread family-directed COVID-19 infection and vaccine-related health information and education targeted against these factors that promote VH are recommended in order to improve vaccine acceptance, and avoid vaccine resistance in the family.
Knowledge, Attitude, and Practices toward First Aid against Occupational Injuries and their Determinants among Agricultural Workers: A Cross-sectional Study
Authors: Kumar Tamminana Sai , Chivukula Satya Kishore 
Published: October 2023

Background:
The hazards faced by agricultural workers are many and varied as the tasks performed by them are likewise diverse. Knowledge of basic first aid (FA) helps in preserving life, preventing the condition from worsening, and promoting recovery. Thus, the present study was conducted to assess the knowledge about and attitude toward basic FA practices against occupational injuries and identify the determinants that promote good FA practices among agricultural workers.

Materials and Methods:
A cross-sectional study was conducted to assess the knowledge about and attitude toward basic FA practices against occupational injuries and identify the determinants that promote good FA practices among agricultural workers. A predesigned pretested semi-structured questionnaire was used which include sociodemographic profile, personal history, knowledge, and attitude regarding basic FA for wounds, fractures, burns, bites, and poisoning. The questionnaire also includes the practices that the workers adopt against occupational injuries.

Results:
In the present study, 15.5% were observed to have good knowledge about the precautions to be taken to prevent occupational injuries. About 27.7% of the study population were showing good FA practice in the event of an occupational injury. Determinants that promote good FA practices observed in the study are literacy (odds ratio [OR] = 160.16, 05% confidence interval [CI] = 9.73–2635.45, P = 0.0004*), participants with >6 km distance from workplace to hospital (OR = 2.19, 95% CI = 1.19–4.03, P = 0.01*). Participants who received FA treatment in the past (OR = 2.95, 95% CI = 1.30–6.67, P = 0.009*).

Conclusion:
Awareness of FA is a low-cost measure through which stakeholders at village, state and national levels, policymakers, and researchers can implement appropriate strategies to reduce injuries among farmers and address their occupational health needs. Because there is little literature on FA awareness among agricultural workers, there is a need to promote FA as a primary preventive measure in preventing the majority of work-related injuries.
Effect of Simulated Gastric Acid on Aesthetical Restorative CAD-CAM Materials’ Microhardness and Flexural Strength
Authors: Gülakar TL , Comert GN , Karaman E , Cakan U , Ozel GS , Ahmet SO 
Published: October 2023

ABSTRACT

Background:
Gastric acid, which is among erosive substances, gradually rises to the mouth in individuals with reflux and bulimia nervosa disorders, and this causes various effects on dental restorations.

Aim:
The objective of this study is in vitro investigation of gastric acid’s effect on flexural strength and hardness on aesthetic restorative computer-aided design and computer-aided manufacturing (CAD-CAM) materials.

Materials and Methods:
For this study, four materials have been used, namely Enamic (Vita), Superfect Zir (Aidite) Zirconia, IPS e.max CAD (Ivoclar Vivadent), and Mark II (Vita). From these four different materials, 24 samples with 14 × 4 × 1 dimensions in rectangular prism form are used, which makes a total of 96 samples. One group was separated as the control group, while the rest was allowed to wait at 37°C, 5 ml gastric acid for 96 hours. Hardness value and flexural strengths were measured as pre-exposure and post-exposure to gastric acid.

Results:
There is a statistically significant difference between the groups in terms of the amount of decrease in the mean hardness after exposure to gastric acid compared to pre-exposure values (p: 0,000; P < 0,05). There was no statistically significant difference between the groups in terms of the amount of decrease in the post-exposure average flexural strength compared to the pre-exposure value (p: 0.063; P > 0.05). There is a statistically significant difference between the groups in terms of the average flexural strength after exposure to the acid.

Conclusions:
According to the data obtained, it was concluded that exposure to gastric acid affects the hardness and flexural strength properties of dental restorative ceramic materials.
Is the BNT162b2 Vaccine Still Effective against the Latest Variant: XBB.1.5?
Authors: Erdag Emine , Sultanoglu Nazife , Ozverel Cenk S. 
Published: October 2023

ABSTRACTBackground:The XBB.1.5 sub-variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron now continues to spread rapidly due to the increased transmission rate as a result of increased affinity of the virus binding over the ACE-2 receptor – a gained property due to the mutation that occurred in spike protein.Aim:The protectivity of BNT162b2 antibodies produced in the serum of patients is an important parameter for preventing transmission. However, the affinity of the antibodies of patients vaccinated with BNT162b2 over the latest SARS-CoV-2 variant, XBB.1.5, is not well established. This study aimed to evaluate the efficacy of the BNT162b2 vaccine-induced antibody on XBB.1.5 by comparing the X-ray crystallographic structures and spike protein mutations of BA.5 and XBB.1.5 usingin silicomethods.Materials and Methods:Binding points and binding affinity values of the BNT162b2 antibody with BA.5 and XBB.1.5 spike protein were calculated using ClusPro 2.0 protein–protein docking and Discovery Studio 2021 Client software. Mutations in the genetic code of the spike protein for SARS-CoV-2 BA.5 and XBB.1.5 sub-variants were screened using the GISAID database.Results:Binding affinity values showed that BNT162b2 had higher negative values in the XBB.1.5 sub-variant than BA.5 at the mutation sites at the binding region. The results suggested that BNT162b2 may retain its activity despite mutations and conformational changes in the binding site of the XBB.1.5.Conclusion:The findings of this study shed light on the importance and usability of the current BNT162b2 vaccine for XBB.1.5 and future variants of concern.
Cases of Hypogonadotropic Hypogonadism: A Single-Center Experience
Authors: Buluş AD , Yaşartekin Y , Ceylan AC , Dirican O , Husseını AA 
Published: October 2023

ABSTRACT

Background:
Delayed puberty (DP) affects approximately 2% of adolescents. In most patients of both genders, delayed puberty is due to constitutional delay in growth and puberty (CDGP); it is a self-limiting condition starting later than usual during puberty but progressing normally. Other causes of DP include permanent hypogonadotropic hypogonadism, functional hypogonadotropic hypogonadism, and gonadal insufficiency.

Methods:
Nine patients admitted to the Ankara Atatürk Sanatoryum Training and Research Hospital Pediatric Endocrinology Department with hypogonadotropic hypogonadism between January 2012 and December 2022 were analyzed.

Results:
Nine patients who applied to our pediatric endocrinology clinic with delayed puberty were analyzed. These nine patients were diagnosed and reported as hypogonadotropic hypogonadism with molecular methods. We aimed to determine the status of these cases from a molecular point of view, to emphasize the importance of hypogonadotropic hypogonadism in patients with delayed puberty, and to reveal the rarely encountered delayed puberty together with the clinical and laboratory data set of the patients.

Conclusions:
To emphasize the importance of hypogonadotropic hypogonadism, which is a rare cause of delayed puberty, the molecular predispositions of our patients followed in our clinic are reviewed, and the data we have provided will contribute to the accumulation of data in this area.
The Relationship between Oral Health and Sleep Quality in Community-Dwelling Older Adults
Authors: Safak E Deniz , Celik F , Mazicioglu MM , Akin S , Manav TY , Kesim S , Ozturk A 
Published: October 2023

ABSTRACT

Introduction:
The assessment of the sleep status of older adults and its relationship to oral health can help determine their well-being and quality of life. In accordance with this purpose, we aimed to evaluate the relationship between oral health and sleep quality in community-dwelling older adults in an urban area.

Materials and Methods:
The data of this study were taken from the Kayseri Elderly Health Study. The study group was administered a questionnaire form and the Pittsburgh Sleep Quality Index. A specialist dentist examined the oral health conditions (dentures use; caries; deficient, filled, natural teeth numbers; periodontal health) using the Community Periodontal Index and the Oral Health Impact Profile-14 (OHIP-14-TR).

Results:
One hundred forty (38.1%) of the study group were female, and 227 (61.9%) were male. When evaluated in terms of oral hygiene, there was a statistically significant difference between those with good sleep quality and poor sleep quality in terms of mechanical interventions such as using toothpaste and an inter-dental brush, and also, OHIP-14-TR was significant. In the binary logistic regression analysis, OHIP-14-TR was found to be a significant risk factor, reflecting only the subjective interpretation of the older adults in terms of oral health-related quality of life (odds ratio: 1.069, 95.0% confidence interval: 1.043–1.096).

Conclusion:
This is the first epidemiologic study to examine the relationship between oral health status and sleep quality, in which many oral health indicators are evaluated together in Turkish community-dwelling older adults. OHIP-14-TR may be a useful tool to employ in sleep disorder clinics for older people.
Clinical trial trends over the last 5 years among the BRICS (Brazil, Russia, India, China, and South Africa) nations
Authors: Manoharan Kaviya , Jinson Juanna , Ramesh Kalaivani , George Melvin 
Published: October 2023

Abstract

Purpose:
Although the Americas and Europe have historically dominated the global research landscape, emerging economies – Brazil, Russia, India, China, and South Africa (BRICS) have significantly increased their contributions in recent years. This article studies clinical trial trends in the BRICS nations between 2018 and 2022 and compares it with trends in the G7 nations (comprising Canada, France, Germany, Italy, Japan, the UK, the USA, and the European Union). This will help stakeholders in planning drug development strategies.

Materials and Methods:
Data were collected from the World Health Organization International Clinical Trials Registry Platform (WHO ICTRP) and the World Bank database. An electronic search was done for the total number of trials registered between January 1, 2018, and March 15, 2023. Information was analyzed based on the year of registration, therapeutic area, type of intervention, sponsorship, and type of special population. The trial density indices (TDIs) were calculated based on population (Xi) and gross domestic product (GDP) (Yi) using author-derived formulae.

Results:
Altogether 2, 77, 536 trials from the BRICS and G7 were registered. China and the US had the most trials among the BRICS and G7, respectively. Between 2018 and 2022, the gap between the BRICS and G7 steadily reduced. The most common indication for clinical trials among the BRICS was cancer. Based on population, the TDI was the highest in China and the lowest in Russia. In proportion to the GDP, the TDI was maximum in Russia and minimum in India.

Conclusion:
There is a remarkable reduction in the gap in clinical trial trends between the BRICS and G7 nations. Among the BRICS, India and China are at the forefront in drug development. There is scope for improvement in trial density based on India’s population and GDP. Stakeholders are likely to utilize the strengths of the BRICS as an attractive destination for investment in this area.
Analisis Semiotika pada Music Video Jkt 48 dengan Judul Benang Sari, Putik dan Kupu-Kupu Malam
Authors: Sari Sri Indah , Ananda Rizki Ayu , Sazali Hasan , Dalimunthe Maulana Andinata 
Published: October 2023

This research focuses on semiotic analysis of music videos which are the pros and cons in society. The music video for JKT 48 is entitled "Stamen and Night Butterflies". The method used in this study is a qualitative method, which includes: ideas, descriptions of meanings, definitions, characteristics, metaphors, symbols, and others. Based on the author's observations and analysis, in the music video there are scenes that are not in accordance with the culture of our country, namely those that lead to LGBT and are inappropriate for viewing by minors. And using the concept of queerbaiting which refers to and implies heterosexual/LGBT relationships because it uses talent that is entirely female.
Keywords: music, symbols, video
Design of Horizontal Shell Core Casting Machine for Small and Medium Enterprise in the Automotive Sector
Authors: Armansyah  , Agus Sudianto  , Budhi Martana  , Satrio Bagas Damar Handito  , Ridwan Bambang Riantio  , Raden Pranaya Didva  , Ferdyanto  
Published: October 2023

The manufacturing industry plays an important role in a country's economy because it can produce high-value products and has the opportunity to create jobs for local communities. In this study, the authors designed a horizontal shell core casting machine for small and medium enterprises in the automotive sector with a productivity of 60 seconds per cycle of products is designed based on requirements needed. This shell core casting machine is a device to produce shell core molds used to manufacture automotive components and parts. The design of this device was focused on engineering design in the form of 2-dimensional drawings and computer aided design models in 3-dimensional form. This study was done in collaboration with a local machinery manufacturer in Karawang district in Indonesia. It is expected from these designs will become a reference to manufacture shell core casting machines to support national industrialization impacted on improving the local community's economy.
Occupational Therapy Practice Guidelines for Adults With Stroke
Authors: Hildebrand Mary W. , Geller Daniel , Proffitt Rachel 
Published: October 2023

Abstract
Importance: Stroke is a leading cause of disability. Occupational therapy practitioners ensure maximum participation and performance in valued occupations for stroke survivors and their caregivers.
Objective: These Practice Guidelines are meant to support occupational therapy practitioners’ clinical decision making when working with people after stroke and their caregivers.
Method: Clinical recommendations were reviewed from three systematic review questions on interventions to improve performance and participation in daily activities and occupations and from one question on maintaining the caregiving role for caregivers of people after stroke.
Results: The systematic reviews included 168 studies, 24 Level 1a, 90 Level 1b, and 54 Level 2b. These studies were used as the basis for the clinical recommendations in these Practice Guidelines and have strong or moderate supporting evidence.
Conclusions and Recommendations: Interventions with strong strength of evidence for improving performance in activities of daily living and functional mobility include mirror therapy, task-oriented training, mental imagery, balance training, self-management strategies, and a multidisciplinary three-stages-of-care rehabilitation program. Constraint-induced therapy has strong strength of evidence for improving performance of instrumental activities of daily living. Moderate strength of evidence supported cognitive–behavioral therapy (CBT) to address balance self-efficacy, long-term group intervention to improve mobility in the community, and a wearable upper extremity sensory device paired with training games in inpatient rehabilitation to improve social participation. Practitioners should incorporate problem-solving therapy in combination with CBT or with education and a family support organizer program.
What This Article Adds: These Practice Guidelines provide a summary of strong and moderate evidence for effective interventions for people with stroke and for their caregivers.
Pengaruh Kualitas Pengajaran, Kualitas Pelayanan akademik dan Lingkungan Belajar Virtual pada Kepuasan Mahasiswa Pascasarjana dalam Perkuliahan Daring
Authors: Manaransyah Grace , Rahman Agus , Rachmawaty Ike Kusdyah 
Published: October 2023

Penting bagi perguruan tinggi untuk memperhatikan kepuasan pengguna jasa pendidikan karena hal ini berkontribusi besar pada kemajuan perguruan tinggi. Kepuasan mahasiswa terhadap pembelajaran daring dipengaruhi oleh kualitas pengajaran, kualitas pelayanan akademik, dan lingkungan belajar. Mahasiswa yang merasa puas dengan ketiga faktor antara lain kualitas pengajaran, kualitas pelayanan akademik, dan lingkungan belajar cenderung memiliki tingkat kepuasan yang lebih tinggi. Namun, masih terdapat kesenjangan penelitian yang perlu diisi, terutama dalam hal mengukur pengaruh masing-masing faktor secara lebih spesifik dan menyeluruh, serta mempertimbangkan faktor lain yang dapat mempengaruhi kepuasan mahasiswa. Tujuan penelitian ini yaitu (1) Untuk mengetahui dan menganalisis pengaruh kualitas pengajaran terhadap kepuasan mahasiswa, (2) Untuk mengetahui dan menganalisis pengaruh kualitas pelayanan akademik terhadap kepuasan mahasiswa, (3) Untuk mengetahui dan menganalisis pengaruh lingkungan belajar terhadap kepuasan mahasiswa, (4) Untuk mengetahui dan menganalisis pengaruh kualitas pengajaran, kualitas pelayanan akademik dan lingkungan belajar secara bersamaan terhadap kepuasan mahasiswa. Jenis penelitian ini adalah penelitian kausalitas dengan pendekatan penelitian metode kuantitatif. Populasi dalam penelitian ini adalah 119 mahasiswa pasca sarjana dengan sampel yang digunakan adalah 30 mahasiswa pasca sarjana. Teknik analisis data yang digunakan adalah uji instrumen, uji asumsi klasik dan uji hipotesis. Hasil penelitian menunjukkan bahwa (1) Kualitas pengajaran berpengaruh secara parsial terhadap kepuasan mahasiswa, (2) Kualitas pelayanan akademik secara parsial berpengaruh terhadap kepuasan mahasiswa, (3) Lingkungan belajar secara parsial berpengaruh terhadap kepuasan mahasiswa, dan (4) Kualitas pengajaran, kualitas pelayanan akademik dan lingkungan belajar secara bersama-sama berpengaruh terhadap kepuasan mahasiswa.