bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Follow-up Study on Coping Strategies and its Association with Relapse Among Alcohol-dependent Patients
Authors: Venkateswaran Sabitha , Thirumalai Ranganathan 
Published: January 2024

Background: Alcohol Dependence Syndrome is a chronic illness that is relapsing in nature. Past research has shown that coping strategies that are specific to alcohol dependence are useful in preventing long-term relapse. This follow-up study is, therefore, an attempt to understand the coping styles and strategies that are associated with relapse among individuals dependent on alcohol. Methods: We aimed to cross-sectionally assess the severity of alcohol dependence and coping styles of Alcohol dependent individuals. One hundred and twenty-seven consecutive patients who satisfied the International Classification of Diseases Tenth Edition (ICD 10) criteria for alcohol dependence and who were above the age of 18 years were included. This study was conducted in the de-addiction outpatient services of a Tertiary care center in South India between April 2019 and June 2020. Our Institutional Ethical Committee granted the approval for this study. We used a self-designed proforma for collecting the socio-demographic details. The Severity of Alcohol Dependence Questionnaire (SADQ) and Coping Orientation to Problems Experienced Inventory (Brief – COPE) were administered. Patients were followed up for six months. Motivation Enhancement Therapy was given to all our participants during their monthly follow-up visit. Descriptive analysis was performed using mean and standard deviation. We used the student t-test and chi-squared test to understand the differences in the coping strategies between relapsed and non-relapsed persons. Spearman’s correlation was used to assess the correlation between the severity of alcohol dependence and coping strategies. A p value of <.05 was taken as significant. Results: Non-relapsed individuals had significantly higher scores on active coping ( p = .008), emotional support ( p = .044), informational support ( p = .017), planning ( p < .001), acceptance ( p = .030), and humor ( p = .001). Relapsed individuals had statistically significant scores on denial ( p = .005), substance use ( p = .024), and self-blame ( p = .012). We found a positive correlation between the severity of alcohol dependence and maladaptive coping strategies ( p < .01). Conclusions: Relapsed individuals were found to have significantly higher maladaptive coping strategies. Non-relapsed individuals exhibited greater adaptive coping styles. Maladaptive coping strategies positively correlated with the severity of alcohol dependence.
Association Between Sleep-related Cognitions, Sleep-related Behaviors, and Insomnia in Patients with Anxiety and Depression: A Cross-sectional Study
Authors: Muthuraman Kavya , Sankaran Avudaiappan , Subramanian Karthick 
Published: January 2024

Background: The cognitive model of insomnia states that worry about sleep contributes to poor sleep quality. Besides worry, beliefs about sleep and maladaptive safety behaviors also affect sleep quality. We aimed to find the association among the presence of insomnia, sleep-related cognitions, and behaviors among patients diagnosed with anxiety or depression. Methodology: The present cross-sectional comparison study included patients with anxiety spectrum or depressive disorders as per the Diagnostic and Statistical Manual for Mental Disorders—fifth edition and healthy controls. Mood status, insomnia severity, sleep quality, dysfunctional beliefs about sleep, maladaptive safety behaviors, and pre-sleep arousal were evaluated using Hamilton Anxiety Scale (HAM-A), Montgomery Åsberg Depression Rating Scale (MADRS), Insomnia Severity Index, Pittsburgh Sleep Quality Index, Dysfunctional Beliefs and Attitudes Sleep Scale (DBAS), Sleep-related Behavior Questionnaire (SRBQ), and Pre-sleep Arousal Scale (PSAS), respectively. A p value ≤.05 was considered statistically significant. Results: Both patients ( n = 80) and controls ( n = 80) were similar in sociodemographic profile, though the sample was predominantly female. Comparison between patients with insomnia ( n = 60), patients without insomnia ( n = 20), and healthy controls ( n = 80) showed that HAM-A and MADRS, DBAS, SRBQ, and PSAS scores were higher in patients with insomnia compared to their counterparts. DBAS and SRBQ scores positively correlated with increasing severity of insomnia. Dysfunctional beliefs regarding sleep (OR: 1.05; 95% CI = 1.00–1.09) and maladaptive behaviors related to sleep (OR: 1.02; 95% CI = 1.00–1.05) predicted insomnia in patients with depression or anxiety. Conclusion: Insomnia in anxiety or depression is associated with illness severity, dysfunctional beliefs regarding sleep, and sleep-related maladaptive behaviors. Maladaptive cognitions and behaviors can independently influence sleep quality.
Influence of vaginal birth on lumbopelvic muscle mechanical properties on urinary incontinence
Authors: Garzón-Alfaro María Teresa , Cruz-Medel Inés , Alcaraz-Clariana Sandra , García-Luque Lourdes , Carmona-Pérez María Cristina , Garrido-Castro Juan Luis , Alburquerque-Sendín Francisco , Rodrigues-de-Souza Daiana Priscila 
Published: January 2024

Objective To identify differences in the muscle mechanical properties of the pelvic floor (PF) and lumbar paravertebral (LP) muscles between young nulliparous and uni/multiparous women. Secondarily, specific behaviors, depending on the presence or absence or urinary incontinence (UI), were also researched. Design Case–control study. Setting Higher education institution. Participants One hundred young women participated, divided into two groups depending on whether they had vaginal birth (nulliparous or uni/multiparous). Each group included women with and without UI. Main measures A muscle mechanical properties (tone, stiffness, decrement—inverse of elasticity—, and viscoelastic properties: relaxation and creep) assessment of the PF and LP muscles were performed with a hand-held tonometer. Results Tone and stiffness of both sides of the PF presented group by UI interaction ( p < 0.05), with uni/multiparous women with UI showing higher tone and stiffness compared to multiparous women without UI. In LP muscles, uni/multiparous women showed greater tone and stiffness on the right and left sides [−2.57 Hz (95% confidence interval −4.42,−0.72) and −79.74 N/m (−143.52,−15.97); −2.20 Hz (−3.82,−0.58) and −81.30 N/m (−140.66-,21.95), respectively], as well as a decrease in viscoelastic properties compared to nulliparous women [relaxation: 2.88 ms (0.31,5.44); creep: 0.15 (0.01,0.30); relaxation: 2.69 ms (0.13,5.25); creep: 0.14 (0,0.28), respectively]. Conclusions Vaginal birth and UI have a differential influence on the muscle mechanical properties of the PF and LP muscles. The determination of muscle mechanical properties by externally applied hand-held tonometry improves the knowledge of the lumbopelvic status, with applicability in clinical and research fields.
Improvement in sustainability: Evidence from the mergers and acquisitions market
Authors: Nguyen Duy Thanh , Michayluk David , Van de Venter Gerhard , Walker Scott 
Published: January 2024

One approach to improve a firm’s Environmental, Social, and Governance (ESG) rating is to acquire a target with a higher relative ESG rating. We explore changes in an acquirer’s ESG rating around merger and acquisition (M&A) announcements and provide empirical evidence of a positive relationship between the change in an acquirer’s ESG rating and the target’s relative ESG rating. Of the three components of an ESG rating, an acquirer’s environmental rating displays the largest increase, with social and governance ratings exhibiting a smaller but still significant post-merger increase. This relationship is weaker for cross-border deals or cross-industry deals. However, deals that are both cross-border and same-industry are associated with a larger increase in an acquirer’s ESG rating. In addition to improved ESG ratings, the acquisition of a firm with a superior ESG rating is also associated with higher bid premiums and improved post-merger financial performance which suggests that acquirers act in shareholders’ best interests. JEL Classification: G14, G34
Preparation and properties of modified zirconium dioxide reinforced poly (butylene adipate-co-terephthalate)
Authors: He Xiao-feng , Nie Guang-zhi , Zhang Shuang , Xie Ya-qi , Ge Tie-jun , Liu Pei-han 
Published: January 2024

Inorganic particles dispersed in the polymer matrix can enhance the strength of polymers. In this paper, 3-Glycidyloxypropyltrimethoxysilane (KH560) and 2-Amino-1,3-propanediol were used to surface modify Zirconium dioxide (ZrO2) to prepare modified Zirconium dioxide (ZrO2), denoted as ZrO2-g. The modified ZrO2-g was characterized by Fourier transform infrared (FTIR) spectroscopy and nuclear magnetic hydrogen (1HNMR) spectroscopy, and the results showed that the modification was successful. Then the PBAT/ZrO2-g composites were synthesized by grafting ZrO2-g into poly (butylene adipate-co-terephthalate) (PBAT) molecular chain segments using in situ copolymerization. The results showed that ZrO2-g acted as a nucleating agent and improved the crystallinity of poly (butylene adipate-co-terephthalate) (PBAT). The rheological behavior analysis showed that the composite viscosity, storage modulus and loss modulus of PBAT/ZrO2-g composites were improved compared to PBAT. The ZrO2-g content had a significant effect on the tensile properties of the composites, and the composites had the highest tensile strength and elongation at break when the ZrO2-g content was 1% wt, reaching 23.27 MPa and 888.89%, respectively, which were increased by 60% and 38%, respectively, compared with PBAT. When the content of ZrO2-g exceeds 1.5 wt%, aggregation phenomenon occurs, which rather reduces the performance of the composites. Meanwhile, the thermal stability of the composites decreases with the increase of ZrO2-g incorporation.
A novel anion exchange membrane comprised of three aromatic units for fuel cells
Authors: Zheng Shanchang , Huang Yue , Hua Yani , Gao Zhan 
Published: January 2024

Anion exchange membrane fuel cell (AEMFC) has made great progress recently due to the continuous improvement of anion exchange membrane (AEM). Aryl ether bond-free membranes are considered to be promising for improving the overall performance of AEMs. Here, we present a copolymer consisting of m-terphenyl, diphenyl ethane and biphenyl (PMDBP) to further enhance the microphase separation structure by introducing a third structural unit, biphenyl. Meanwhile, the more compact biphenyl structure enhances the mechanical strength of AEMs. Specifically, PMDBP AEMs possess superior OH- conductivity (up to 113 mS cm−1) and excellent mechanical properties (tensile strength up to 42 MPa). Furthermore, the PMDBP has an outstanding single-cell performance with a peak power density (PPD) of up to 95 mW cm−2 with a platinum-carbon (Pt/C) catalyst at 80°C in H2-air. In addition, PMDBP is provided with excellent durability, including NMR spectral consistency and over 90% ion conductivity retention in 1 M NaOH at 60°C for 720 h. This study provided a copolymer structure suitable for anion exchange membrane that can provide excellent performance for fuel cells and electrolyzers.
Prevalence, risk factors and genotyping of chlamydia trachomatis from endocervical specimens of infertile women at a tertiary care hospital, Vietnam
Authors: Nguyen Hoa , Do Ngoc Anh , Nguyen Le Van , Nguyen Thi Nhu Quynh , Hoang Thi Yen , Hoang Canh Dinh , Tran Quang Phuc , Vu Van Du 
Published: January 2024

Background To our knowledge, the prevalence, risk factors and distribution of C. trachomatis genotypes are rarely mentioned in Vietnam. This study aimed to find the prevalence, risk factors and distribution of C. trachomatis genotypes in infertile Vietnamese women. Methods Endocervical swabs were collected from infertile women at the National Hospital of Obstetrics and Gynecology, Vietnam, between January 2020 and December 2021. All samples were analyzed for C. trachomatis presence by Cobas 4800 CT/NG Test. Sequencing methods of ompA gene were used to determine the C. trachomatis genotypes. An approximately 1200 bp ompA fragment was aligned with reference sequences from GenBank to identify the corresponding genotype. Results The prevalence of endocervical C. trachomatis infection was 15.6% of 761 participants. Factors independently associated with CT infection among infertile women, obtained by multivariate analysis, included abnormal vaginal discharge, cervicitis, lower abdominal pain, a history of ectopic pregnancy, having more than one sex partner, and age at first intercourse. Among the samples, genotype E (25.93%) was most frequently found, followed by genotypes D/Da (22.23%), F (13.58%), G/Ga (12.35%), J (12.35%), H (6.17%), K (3.70%), B/Ba (2.47%), and I/Ia (1.23%), respectively. Genotype F was related to types of infertility, and genotype H was associated with a history of miscarriage. Conclusions The present study indicated a high prevalence of C. trachomatis in infertile Vietnamese women. The most common genotypes found in this population were E, D, and F. Our findings suggest that routine screening is necessary for early detection and performance of infection control methods.
The prognostic potential of mammographic growth rate of invasive breast cancer in the Nijmegen breast cancer screening cohort
Authors: Peters Jim , van Dijck Jos A.A.M. , Elias Sjoerd G. , Otten Johannes D.M. , Broeders Mireille J.M. ,   on behalf of the IMAGINE Consortium
Published: January 2024

Objectives Insight into the aggressiveness of potential breast cancers found in screening may optimize recall decisions. Specific growth rate (SGR), measured on mammograms, may provide valuable prognostic information. This study addresses the association of SGR with prognostic factors and overall survival in patients with invasive carcinoma of no special type (NST) from a screened population. Methods In this historic cohort study, 293 women with NST were identified from all participants in the Nijmegen screening program (2003–2007). Information on clinicopathological factors was retrieved from patient files and follow-up on vital status through municipalities. On consecutive mammograms, tumor volumes were estimated. After comparing five growth functions, SGR was calculated using the best-fitting function. Regression and multivariable survival analyses described associations between SGR and prognostic factors as well as overall survival. Results Each one standard deviation increase in SGR was associated with an increase in the Nottingham prognostic index by 0.34 [95% confidence interval (CI): 0.21–0.46]. Each one standard deviation increase in SGR increased the odds of a tumor with an unfavorable subtype (based on histologic grade and hormone receptors; odds ratio 2.14 [95% CI: 1.45–3.15]) and increased the odds of diagnosis as an interval cancer (versus screen-detected; odds ratio 1.57 [95% CI: 1.20–2.06]). After a median of 12.4 years of follow-up, 78 deaths occurred. SGR was not associated with overall survival (hazard ratio 1.12 [95% CI: 0.87–1.43]). Conclusions SGR may indicate prognostically relevant differences in tumor aggressiveness if serial mammograms are available. A potential association with cause-specific survival could not be determined and is of interest for future research.
Cortical Bone Thickness and Morphology at the Infrazygomatic Crest Area in Growing Thai Patients with UCLP: A CBCT Study
Authors: Phusantisampan Ploypailin , Chaiworawitkul Marasri 
Published: January 2024

Objectives To determine and compare buccal cortical bone thickness and morphology (in terms of shape and height) at the infrazygomatic (IZ) crest in growing Thai patients with unilateral cleft lip and palate (UCLP) using cone-beam computed tomography (CBCT) with the ultimate goal of identifying potential sites that are suitable for the placement of miniplates. Design Prospective study. Settling Institutional research. Patients Twenty-four Thai patients with non-syndromic complete UCLP with Class III skeletal discrepancy aged 10-14 years. Interventions A total of 48 CBCT images captured the IZ crest. Five horizontal and six vertical reference planes were established in the IZ crest area. Main Outcome Measure The mean buccal cortical bone thickness of the cleft and non-cleft sides were 1.13 ± 0.45 mm and 1.15 ± 0.46 mm, respectively. The most frequently observed shape for the IZ crest was the external concave contour. There were no statistically significant differences in cortical bone thickness and shape distribution between the cleft and non-cleft sides. ( P > .05). Results The thickness of the buccal cortical bone increased anteriorly and superiorly from V + 0 and H + 0. The average height of IZ crest on the cleft side was 16.20 ± 1.59 mm and 16.78 ± 1.84 mm on the non-cleft side. Notably, significant differences were detected in terms of height between the cleft and non-cleft side and cortical bone thickness by gender ( P < .05). Conclusions The IZ crest was found to provide sufficient support for the insertion of a miniplate, particularly in the superior and anterior regions, ensuring primary stability in growing Thai patients with UCLP.
Concordance analysis of two databases to search for potential drug interactions in onco-hematologic patients
Authors: Moreira Pryscila Rodrigues , de Farias Leonardo Teodoro , Feitosa Amanda Ribeiro , Silva Lunara Teles , Ferreira Tatyana Xavier Almeida Matteucci , Provin Mércia Pandolfo , Amaral Rita Goreti , Modesto Ana Carolina Figueiredo 
Published: January 2024

Introduction Potential drug interactions exert a significant impact on patient safety, especially within intricate onco-hematological treatments, potentially resulting in toxicity or treatment failures. Despite the availability of databases for potential drug interaction investigation, persistent heterogeneity in concordance rates and classifications exists. The additional variability in database agreement poses further complexity, notably in critical contexts like onco-hematology. Aim To analyze the concordance of two databases for researching potential drug interaction in prescriptions for hematological patients at a University Hospital in the Midwest region of Brazil. Method Cross-sectional study developed in a Brazilian hospital. The search for potential drug interaction was conducted in Micromedex® and UpToDate®. The variables were: the presence of potential drug interaction, severity, mechanism, management, and documentation. Data was analyzed in terms of frequency (absolute and relative), Cohen's kappa, and Fleiss kappa . Results The presence of potential drug interaction, showed a lack of concordance between the databases ( k = −0.115 [95% CI: 0.361–0.532], p = 0.003). Regarding the mechanism, a strong agreement was observed ( k = 0.805, p < 0.001 [95% CI: 0.550–0.941]). The management concordance showed a fair agreement, 46.8% ( k = 0.22, p < 0.001 [95% CI: 0.099–0.341]). Stratifying the categories, significant concordance was observed in “Adjustment of dose + Monitoring” ( k = 0.302, p = 0.018) and “Monitoring” ( k = 0.417, p = 0.001), while other categories did not reach statistical significance. Conclusion Our study emphasizes the variability in potential drug interaction research, revealing disparities in severity classification, management recommendations, and documentation practices across databases.
Effects of Stimulant Treatment on Changes in Brain Activation During Reward Notifications in Drug Naïve Youth With ADHD
Authors: Ivanov Iliyan , Krone Beth , Schulz Kurt , Shaik Riaz B. , Parvaz Muhammad A. , Newcorn Jeffrey H. 
Published: January 2024

Background: Research examining the potential effects of stimulant exposure in childhood on subsequent development of substance use disorder (SUD) have focused on differences in the brain reward system as a function of risk. Methods: 18 drug naïve children ages 7 to 12 years (11 High Risk [ADHD + ODD/CD]; 7 Low Risk [ADHD only]), underwent fMRI scans before and after treatment with mixed amphetamine salts, extended release (MAS-XR). We examined correlations between clinical ratings and fMRI activation at baseline and following treatment as a function of risk status. Results: High Risk children had higher activation than Low Risk children at baseline during both the Reward and Surprising Non-Reward conditions. Treatment produced strong differential effects on brain activation pertinent to group and reward outcome. Conclusions: Findings support the hypothesized role of reward mechanisms in SUD risk, and suggest that stimulant treatment may have differential effects on reward processing in relation to SUD risk.
Bilateral central retinal vein occlusion following COVID-19 vaccination: Cause or coincidence?
Authors: Matri Khaled El , Werda Slim , Chebbi Zouheir , Saidane Rahma , Doukh Meryem , Choura Racem , Falfoul Yousra , Limaiem Rim , Matri Leila El 
Published: January 2024

AimTo report a case of sequential bilateral ischemic central retinal vein occlusion (CRVO) following the third dose of anti-COVID 19 vaccination.MethodsObservational case report.ResultsA 73-year-old Caucasian male patient, with no known medical history, complained of sudden vision loss in his right eye (RE) 18 days following the third dose of Pfizer-BioNTech anti-COVID 19 vaccination. Ten days later, he suffered from sudden vision loss in his left eye (LE). Best-corrected visual acuity was limited to counting fingers at 50cm in both eyes. Fundus examination of both eyes revealed signs of ischemic central retinal vein occlusion (CRVO) with diffuse superficial and deep retinal hemorrhages in all four quadrants. Diagnosis was confirmed of fluorescein angiography. Optical coherent tomography (OCT) showed an ischemic hyperreflectivity and disorganization of the inner retinal layers in both eyes with significantly increased central macular thickness, associated to intraretinal fluid accumulation in LE. An urgent systemic assessment was requested. A mild hypertension was discovered and the rest of the work up was unremarkable.ConclusionTo our knowledge, we report the first case of bilateral CRVO in a healthy patient after anti-COVID 19 vaccination. CRVO occurred few days following third shot of vaccine followed by a sequential CRVO in the fellow eye in a patient with recently diagnosed very mild hypertension and no thrombo-embolic risk factors, strongly suggesting a relationship between both events. Nowadays, CRVO should be kept in mind as a potential side effect of Covid-19 vaccination and should be added to the spectrum of their ophthalmic complications.