bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pathogenic, Total Loss-of-Function DYRK1B Variants Cause Monogenic Obesity Associated With Type 2 Diabetes
Authors: Folon Lise , Baron Morgane , Scherrer Victoria , Toussaint Bénédicte , Vaillant Emmanuel , Loiselle Hélène , Dechaume Aurélie , De Pooter Frédérique , Boutry Raphaël , Boissel Mathilde , Diallo Aboubacar , Ning Lijiao , Balkau Beverley , Charpentier Guillaume , Franc Sylvia , Marre Michel , Derhourhi Mehdi , Froguel Philippe , Bonnefond Amélie 
Published: January 2024

OBJECTIVE
Rare variants in DYRK1B have been described in some patients with central obesity, type 2 diabetes, and early-onset coronary disease. Owing to the limited number of conducted studies, the broader impact of DYRK1B variants on a larger scale has yet to be investigated.

RESEARCH DESIGN AND METHODS
DYRK1B was sequenced in 9,353 participants from a case-control study for obesity and type 2 diabetes. Each DYRK1B variant was functionally assessed in vitro. Variant pathogenicity was determined using criteria from the American College of Medical Genetics and Genomics (ACMG). The effect of pathogenic or likely pathogenic (P/LP) variants on metabolic traits was assessed using adjusted mixed-effects score tests.

RESULTS
Sixty-five rare, heterozygous DYRK1B variants were identified and were not associated with obesity or type 2 diabetes. Following functional analyses, 20 P/LP variants were pinpointed, including 6 variants that exhibited a fully inhibitory effect (P/LP-null) on DYRK1B activity. P/LP and P/LP-null DYRK1B variants were associated with increased BMI and obesity risk; however, the impact was notably more pronounced for the P/LP-null variants (effect of 8.0 ± 3.2 and odds ratio of 7.9 [95% CI 1.2–155]). Furthermore, P/LP-null variants were associated with higher fasting glucose and type 2 diabetes risk (effect of 2.9 ± 1.0 and odds ratio of 4.8 [95% CI 0.85–37]), while P/LP variants had no effect on glucose homeostasis.

CONCLUSIONS
P/LP, total loss-of-function DYRK1B variants cause monogenic obesity associated with type 2 diabetes. This study underscores the significance of conducting functional assessments in order to accurately ascertain the tangible effects of P/LP DYRK1B variants.
The Lviv Archaeological Milieu During World War
Authors: Bulyk Natalia , Berest Roman 
Published: January 2024

The article deals with the scientific and museological activities of Lviv archaeologists during World War I. The focus is on the fate of archaeologists who were forced to serve in the army (Y. Pasternak, V. Hrebeniak); the state of scientific institutions of Lviv, and the living and working conditions of professors and teaching staff of the University of Lviv, as well as museum workers of the city, were analyzed. In addition, it is about stocking and inventorying the museum collections with archaeological finds, and attempts to restore the activities of museum institutions regardless of conditions (National Museum of Jan III Sobieski, Dzieduszycki Museum). The issue of the loss of human lives is not the least. During these years, Lviv archaeology lost a Polish professor of archaeology Karol Hadaczek and his student, the talented Ukrainian archaeologist Volodymyr Hrebeniak. It was found that the War stopped the development of archaeological science in Lviv and pushed it back for some time. Only in the post-War years, was it possible to restore field research, and publishing activities, replenish museum collections, and educate new personnel.
Servur'a and Krym'a (Crimean Roma) as Indigenous Peoples of Ukraine
Authors: Panchenko Janush , Homanyuk Mykola 
Published: January 2024

The article presents an ethnographic and sociological description of two sub-ethnic groups of Ukrainian Roma: Sérvur’a and Krým’a (Crimean Roma). Based on the field research conducted in 2016–2022, we have concluded that the Krym’a and the Servur’a are (sub-) ethnic groups which meet most of the national and international criteria for being regarded as indigenous people of Ukraine. Servur’a and Krýmʼa were both formed in the territory of Ukraine, are predominantly based in Ukraine, are bearers of distinctive languages and cultures, have traditional, social, cultural and/or representative bodies, identify as (indigenous) people of Ukraine, as is reflected in their self-names; each of them is an ethnic minority within the population of Ukraine, and neither has a state formation of its own outside of Ukraine. Therefore, they fully satisfy the requirements of the relevant Ukrainian legislation. Additional grounds for classifying Servur’a and Krym’a as indigenous peoples are their non-dominant position in society, their traumatic historical experience, which includes the Holocaust of the Roma, the 1944 deportation of the Crimean peoples, as well as their vulnerability to forced displacement from their historic lands and the fact that the Krym’a became refugees and internally displaced persons as a result of the Russian-Ukrainian war. In the authors’ opinion, the initiation of the discussion on granting indigenous status to the Servur’a and the Krym’a can draw attention to the urgent problems of all Romani ethnic groups in Ukraine and give impetus to the formation of the state’s policy towards the Roma.
Review of Zbigniew Marcin Kowalewski, Ukraińskie Rewolucje [Eng. Ukrainian Revolutions], Instytut Wydawniczy Książka i Prasa, Warsaw 2022.
Authors: Jóźwiak Ignacy 
Published: January 2024

This is a review of a book by Zbigniew Marcin Kowalewski, Ukraińskie Rewolucje [Eng. Ukrainian Revolutions] published by Instytut Wydawniczy Książka i Prasa, Warsaw 2022.
Metastatic Neuroblastoma with Initial Orbital Presentation
Authors: Laabi Imane , El Alami Meriem , Baqadir Chaimae , Laftimi Zyad , Daghouj Ghizlane , El Maaloum Loubna , Allali Bouchra , El Kettani Asmae 
Published: January 2024

Neuroblastoma, also called sympathoblastoma, is a malignant embryonal tumor developed at the expense of neural crest cells, the most frequent solid tumor in children under 5 years of age.
The objective is to recall the clinical variability and the importance of evoking neuroblastoma in a child presenting with an ophthalmological symptom.
We report the case of a 5-year-old child who presented with a right orbital metastatic neuroblastoma, whose ophthalmologic complaint led to the diagnosis.
An ophthalmologist in the emergency room for a VAD and eye pain first saw the child. On examination, true exophthalmos with palpebral edema was found on the right. Cerebral and orbital CT revealed a right latero-orbital osteolytic mass of secondary appearance with endocranial extension. The workup showed lymph node involvement, unilateral right adrenal, osteomedullary, hepatic, and pancreatic involvement.
The child was admitted to a specialized pediatric oncology department and received chemotherapy. The patient was then declared under palliative treatment.
“Gender and Violence in Vijay Tendulkar’s Sakharam Binder (1972)”
Authors: Gupta Anamika 
Published: January 2024

In the developmental procedure of culture and civilization, human beings are divided into men and women. Both of them suppress their impulsiveness and spontaneity and lose the real delight of life by adopting the ways of culture and social norms. Man becomes the head of the family. He controls and presides over all its affairs. He becomes the master that in due course leads to the formation of male biased society that oppresses womankind all over the globe.Vijay Tendulkar in most of his foremost plays presents women as victim. Women’s place is of greatest concern to Vijay Tendulkar because of the abysmal difference that women experience in relation to men. Vijay Tendulkar depicts the diurnal humiliations and abasements that women undergo in this male chauvinist society. This paper is an attempt to expose the tyranny or oppressive nature of Gender in the play Sakharam Binder (1972) by Vijay Tendulkar that leads to violence (Physical, Sexual and Psychological) due to social and gender inequality. Tendulkar reveals the dramatic tension among Sakharam and Laxmi and Champa. This play depicts the life in all its nefariousness, ugliness, primitiveness and crudity. It explores the complexities of human nature. This play is a study in human violence, antagonism and terror, in how people try to keep down and oppress one another at the first opportunity. Moreover, Tendulkar reaches into the depth of physical lust and violence in human beings. Tendulkar depicts violence not only in form of physical cruelty and sexual violence but also tries to explore the real causes and deep-rooted sources, which are responsible for such kind of violence.
PENGARUH LOVE OF MONEY, SIFAT MACHIAVELLIAN DAN TINGKAT PENGETAHUAN AKUNTANSI TERHADAP PERSEPSI ETIS MAHASISWA AKUNTANSI
Authors: Isa Alma Choiril , Endri Nedi H , Sari Gustin Padwa 
Published: January 2024

This research was conducted to determine the effect of love of money, machiavellian character and the level of accounting knowledge on the ethical perceptions of accounting students (a case study of accounting students at Muhammadiyah University of Metro). The research method in this research was quantitative. The sample used in this study were accounting students in the seventh semester (VII). By using purposive sampling technique in sampling, in order to obtain a sample of 68 respondents. The data were processed using the SPSS.20 output with multiple linear regression analysis. The result obtained was that the machiavellian nature influenced on the ethical perceptions of accounting students. Meanwhile, love of money and the level of accounting knowledge had no effect on the ethical perceptions of accounting students.
PENGARUH ACADEMIC SELF EFFICACY, KONFORMITAS, DAN FRAUD DIAMOND TERHADAP PERILAKU KECURANGAN AKADEMIK MAHASISWA AKUNTANSI
Authors: Ermalia Elda Desi , Hendri Nedi , Darmayanti Elmira Febri 
Published: January 2024

Penelitian yang berjudul “Pengaruh Academic Self Efficacy, Konformitas, dan Fraud Diamond Terhadap Perilaku Kecurangan Akademik Mahasiswa Akuntansi (Studi Kasus Pada Mahasiswa S1 Akuntansi Universitas Muhammadiyah Metro).” Dengan Metode Kuantitatif, yang bertujuan untuk mengetahui adanya perilaku kecurangan akademik yang dilakukan oleh mahasiswa S1 Akuntansi angkatan 2016 sampai 2020 yang berjumlah 321 dengan 76 responden di Fakultas Ekonomi dan Bisnis, Universitas Muhammadiyah Metro. Berdasarkan hasil penelitian yang diperoleh data hasil Academic Self Efficacy (X1), Konformitas (X2), Fraud Diamond (X3), Perilaku Kecurangan Akademik Mahasiswa Akuntansi (Y) sebesar 52.6% , dan sisanya dipengaruhi independen lainnya sebesar 47.4%. Dari variabel dependen udan independen menunjukkan pengaruh positif dari dependen lebih dominan daripada independen.
Influence of Window Roller Blinds on Energy Consumption in Residential Buildings in Serbia
Authors: Djoković Jelena M. , Nikolić Ružica R. , Bokůvka Otakar , Pastorková Jana 
Published: January 2024

Abstract
Roller blinds are devices that are retracted and wrapped in a box above the window opening and are used to protect against the solar radiation. Those are the wellknown devices with distinct advantages over the fixed external dimming elements. The influence of external blinds on the internal thermal environment in climatic conditions in the Republic of Serbia, the city of Kragujevac, was considered in this research. An external blind was installed in the test room and its influence on the internal temperature was compared with the internal temperature of the room without the blind. Real-time monitoring was carried out in February and August 2023. The results presented in this paper show that the blind reduces the temperature in summer by 3.57ºC and increases it in winter by 1.76ºC. The cooling load can be reduced by about 20%, and the heat load by about 15%.
Analysis and Assessment of Threats Existing in Selected Small Sports and Recreational Infrastructure Facilities Using Quality Management Tools
Authors: Jagusiak-Kocik Marta 
Published: January 2024

Abstract
The aim of the work was to determine the effectiveness of the use of the Ishikawa diagram and the Pareto-Lorenz diagram in the analysis and assessment of threats that occur in small sports and recreation infrastructure - playgrounds. After analysing the available literature, it can be concluded that there are studies in the field of safety on playgrounds, but there are no publications combining surveys with the use of quality management tools in relation to this topic. Through a direct survey conducted among parents and caregivers, information was obtained about the threats in playgrounds located near housing estates they meet most often. Using the Ishikawa diagram, this information was grouped and a brainstorming session was conducted to isolate the root causes of these threats. After conducting an analysis using the Pareto-Lorenz diagram, the threats that appeared most frequently in the respondents' responses were specified. The result of the work is to propose actions that can reduce or eliminate these threats.
The Impact of Ergonomics on Quality of Life in the Workplace
Authors: Marková Petra , Škurková Katarína Lestyáska 
Published: January 2024

Abstract
People spend most of their adult lives in the workplace and at work. It is therefore essential to create an environment and working conditions that positively affect their work performance and well-being at work. Ergonomics is the science that studies the relationship between people and the environment that surrounds them on a daily basis. It is not only about achieving optimum work performance, but for companies ergonomics can save costs associated with health problems and physical and psychological illnesses of employees due to poor quality of life in the workplace. Even today, with the implementation of Industry 4.0 and increasing levels of automation and robotization, technological developments are enabling efficient production processes and bringing about changes in human work. With this comes the emergence of new threats to employee well-being and challenging their existing skills and knowledge. It is therefore essential to provide quality workplaces for the workforce that will be work-ing in the changed environment. The aim of this paper is to present how ergonomic rationalisation can be used to influence the quality of life in the workplace so that employees are able to perform optimally at work without negatively impacting on their health.
Proposal of the E-Services Quality Scale – Preliminary Results
Authors: Ingaldi Manuela 
Published: January 2024

Abstract
Quality plays a crucial role in both e-commerce and online stores because customers expect not only convenient shopping but also satisfaction with products and services. High-quality services and products contribute to increased customer loyalty and the establishment of a positive company image in the competitive online market. In the case of e-commerce, the main attributes considered when evaluating quality are those related to the functioning of the website through which the customer orders products. The main goal of the study was an attempt to compile attributes that would reflect the quality of a specific e-service, especially an e-commerce store, and influence customer satisfaction. Based on the list of attributes, an effort was made to identify those most important to customers. The research results, the importance of individual attributes and groups, further demonstrate what customers pay particular attention to in e-shops and what matters to them. Emphasizing the fulfillment of these attributes is crucial.
Evaluating Occupational Hazards and Prevention Strategies in Agriculture: Case Study
Authors: Pilarczyk Maria , Ulewicz Rober 
Published: January 2024

AbstractThis article explores the multifaceted issues of occupational hazards in agriculture, focusing on common causes, circumstances of accidents, and preventive measures. Agriculture is recognized as one of the most hazardous industries, second only to construction. The study delves into the reasons for the high incidence of accidents, which include a tolerance for risky behaviors, poor engagement, lack of proper risk assessment, and inadequate safety regulations. By analyzing data from the International Labour Organization and other relevant sources, the research identifies the primary risks faced by agricultural workers, such as mechanical, chemical, biological hazards, and accidents involving animals and machinery. The findings highlight the necessity of comprehensive safety education, technological improvements, and legal regulations to mitigate these risks. The goal is to provide a thorough understanding of the current safety landscape in agriculture and to propose actionable strategies to enhance occupational safety and health.
Study on Safety Management in Turkish Earthquakes
Authors: Stasiak-Betlejewska Renata , Ömek Gökhan 
Published: January 2024

Abstract
Natural disasters affect not only humans but also all living beings and societal elements. The term "disaster “meaning a Great Calamity. Among these calamities, earthquakes stand out as the most significant in terms of the damages they cause. Internationally, all authorities define earthquakes as the disasters that result in the highest loss of life and property. This paper highlights the urgent need for effective debris management measures, drawing on established scientific knowledge and operational experience from scientific studies authored by universities. By highlighting the challenges faced during earthquake debris management and safety management and the associated threats to public health and the environment, this study was undertaken to raise people's awareness against similar negligence in future catastrophic events.
Laser Surface Texturing: Characteristics and Applications
Authors: Artur Kalinowski , Norbert Radek , Łukasz Orman , Jacek Pietraszek , Marcin Szczepaniak , Jozef Bronček 
Published: January 2024

Abstract
Laser surface texturing (LST) has emerged as a versatile and efficient technique for modifying surface properties across various materials. This paper provides an analysis of the characteristics and diverse applications of laser surface texturing. The paper begins by explaining the fundamental principles underlying LST, highlighting the mechanisms involved in material interaction and the resultant surface modifications. It explores the influence of laser parameters such as pulse duration, energy density, and wavelength on the texturing process, emphasizes their impact on surface morphology, roughness, and topographical features. Furthermore, this paper delves into the wideranging applications of LST across different industries and fields. It examines how LST enhances surface functionalities, including improvements in tribological properties, wettability, friction reduction, and biocompatibility. Additionally, the utilization of LST for creating microstructures enabling advanced functionalities in optics, electronics, biomedical devices, and energy harvesting systems is discussed. Moreover, the challenges and future directions in LST technology are highlighted, which encompass advances in precision, scalability, and integration of LST with other manufacturing processes. The potential environmental implications and economic feasibility of LST are also discussed.
In summary, this paper examines the characteristics, applications, challenges, and future prospects of laser surface texturing, showcasing its significance as a promising technology for tailoring surface properties across diverse materials and industries.
Critical Analysis of Pool Boiling Correlations
Authors: Radek Norbert , Orman Łukasz J. , Honus Stanislav , Pietraszek Jacek 
Published: January 2024

Abstract
The manuscript describes the problem of boiling heat flux determination with the focus on nucleate boiling mode. It presents the boiling phenomenon on the bare surface and provides a review of the correlations that can be used for modelling purposes. Two most commonly applied correlations were validated against the experimental results. One of them showed significant discrepancies, which might be attributed to the conditions of the research and possible variations in the morphology of the heater. The other correlation proved to be successful in determining heat flux.
Trademarks and Industrial Designs Management in European Industry in the Context of Industrial Property Safety
Authors: Stasiak-Betlejewska Renata , Halima Imane Ben , Betlejewska Oliwia 
Published: January 2024

Abstract
Utilization of companies trademarks and industrial designs in the market strengthens activities of selected companies. Authors of the paper analyse the significance of a trademark and industrial design for the level of the company's industrial property safety. The threats resulting from the lack of trademark registration were identified and analysed, and selected cases from the case law in the field of trademark protection were reviewed to indicate the scope of protection and safety of products placed on the market.
Pengaruh Fasilitas Belajar dan Motivasi Belajar terhadap Hasil Belajar Siswa Jurusan Tata Busana Kelas XI Tata Busana di SMKN 1 Gegerbitung
Authors: Supriatna Endang , Rahayu Sri 
Published: January 2024

Penelitian ini bertujuan untuk mengetahui Pengaruh Fasilitas Belajar Dan Motivasi Belajar Terhadap Hasil Belajar Siswa Mata Pelajaran Pembuatan Busana Industri. Jenis penelitian yang peneliti gunakan adalah penelitian kuantitatif dengan melakukan pendekatan korelasional. Lokasi pada penelitian ini yaitu dilaksanakan di sekolah SMKN 1 Gegerbitung. Populasi yakni semua siswa kelas XI jurusan tata busana dengan berjumlah 33 orang. Sampel menggunakan (total sampling) sehingga sampel sebanyak 33 orang. Metode pengumpulan data yang digunakan dalam penelitian ini adalah sebagai berikut: 1) Observasi , 2) Dokumentasi, 3) Kuesioner. Hasil penelitian ini menampilkan kalau fasilitas belajar serta motivasi belajar berpengaruh positif terhadap hasil belajar siswa pada mata pelajaran pembuatan busana industri di SMKN 1 Gegerbitung. Perihal ini dibuktikan dengan variabel fasilitas belajar mendapatkan nilai sebesar thitung 2,681 serta motivasi belajar mendapatkan nilai sebesar 3,162 thitung lebih besar dari nilai ttabel 2,042. Tidak hanya itu, nilai signifikansi variabel fasilitas belajar 0, 012 serta motivasi belajar 0, 000, yang berarti fasilitas belajar serta motivasi belajar berpengaruh positif terhadap hasil belajar siswa mata pelajaran pembuatan busana industri pada siswa kelas XI tata busana di SMKN 1 Gegerbitung.
Kata kunci : Fasilitas Belajar, Motivasi Belajar, Hasil Belajar