bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between fish body and sagittal otolith morphometrics in the pool barb Puntius sophore (Hamilton, 1822) from the Ganga and Punpun rivers of Bihar, India
Authors: Jaspreet singh  , Ahirwal S. K. , Tarkeshwar Kumar  , Vivekanand Bharti  , Pranab Gogoi  , Kamal Sarma  
Published: November 2023

The present study estimated the morphometric relationships between body and sagittal otolith of the economically and nutritionally important pool barb Puntius sophore (Hamilton, 1822). A total of 266 fish specimens were collected monthly from the Ganga and Punpun rivers of Bihar, India from September 2021 to March 2022 Length-weight relationships (LWRs), length frequency distribution, condition factor and otolith aspect ratio were assessed. The fish length and weight ranged from 5.57 cm to 11.17 cm and 1.18 g to 18.98 g, respectively. The b value in LWRs (b>3) were estimated as 3.20 and 3.17 for Ganga and Punpun, respectively. Condition factors indicated optimal growth conditions for this species in both the rivers. The fish and otolith morphometrics showed a positive correlation, and the highest coefficient of determination (R2) was observed between total fish length and otolith weight (R2= 0.942) followed by fish length and otolith length (R2=0.90). All of these relationships are significant to fisheries management and useful for future time series studies on food-feeding habits, stock structure, environmental change and resource conservation.
Keywords : Coefficient of determination, Condition factor, Fish otolith, Growth, Length-weight relationship
Preservative effect of ready to disperse bioactive edible coating powder from fish protein hydrolysate incorporated with chitosan and active clove oil on tuna fillets (Thunnus albacares) during chilled storage
Authors: Sathish Kumar K. , Bindu J. , Elavarasan K. , Balange Amjad K. , Narasimhamurthy L. 
Published: November 2023

Developing bioactive edible coatings is an emerging trend to improve nutritional value, food quality, and safety. The present work was undertaken to develop ready to disperse bioactive edible coating (BEC) powder from fish protein hydrolysate incorporated with chitosan and clove oil, and to evaluate their preservative effect (10 and 20% level) on tuna fillets during chilled storage at 4°C. Microbiological, biochemical, and sensory evaluation were carried out during 18 days of storage study. Aerobic plate count of tuna fillets treated with 10 and 20% BEC solutions showed 5.45±0.007 log cfu g-1 and 5.33±0.009 log cfu g-1, respectively at the end of storage, whereas the control sample reached 9.25±0.004 log cfu g-1. Among the BEC solution treated samples, 20% BEC solution treated sample had the lowest TBARS (Thiobarbituric acid reactive substances) value (1.68±0.04 mg MDA kg-1) followed by 10% BEC solution treated sample (1.93±0.02 mg MDA kg-1) at the end of the storage, while the control sample exceeded the acceptable limit (2.388±0.167248 mg MDA kg-1) on 9th day itself, which gave clear evidence that BEC solutions effectively extended the tuna fillet’s shelf-life. The overall study revealed that the sample treated with BEC solutions showed an excellent preservative effect on tuna fillets, which indicates the potential of combined use of these agents in food products.
Keywords: Bioactive edible coating, Biochemical analysis, Chilled Storage, Sensory evaluation, Tuna fillets
The Role of Diffusion on Reservoir Performance in Underground Hydrogen Storage
Authors: Arekhov Vladislav , Clemens Torsten , Wegner Jonas , Abdelmoula Mohamed , Manai Taoufik 
Published: November 2023

Summary
Underground hydrogen storage (UHS) has the potential to balance fluctuating sustainable energy generation and energy demand by offering large-scale seasonal energy storage. Depleted natural gas fields or underground gas storage fields are attractive for UHS as they might allow for cost-efficient hydrogen storage. The amount of cushion gas required and the purity of the backproduced hydrogen are important cost factors in UHS.
This study focuses on the role of molecular diffusion within the reservoir during UHS. Although previous research has investigated various topics of UHS such as microbial activity, UHS operations, and gas mixing, the effects of diffusion within the reservoir have not been studied in detail. To evaluate the composition of the gas produced during UHS, numerical simulation was used here. The hydrogen recovery factor and methane-to-hydrogen production ratio for cases with and without diffusive mass flux were compared. A sensitivity analysis was carried out to identify important factors for UHS, including permeability contrast, vertical-to-horizontal permeability ratio, reservoir heterogeneity, binary diffusion coefficient, and pressure-dependent diffusion. Additionally, the effect of numerical dispersion on the results was evaluated.
The simulations demonstrate that diffusion plays an important role in hydrogen storage in depleted gas reservoirs or underground gas storage fields. Ignoring molecular diffusion can lead to the overestimation of the hydrogen recovery factor by up to 9% during the first production cycle and underestimation of the onset of methane contamination by half of the back production cycle. For UHS operations, both the composition and amount of hydrogen are important to design facilities and determine the economics of UHS, and hence diffusion should be evaluated in UHS simulation studies.
Does the use of phytostimulants and the cutting times influence the productivity of the soybean crop?
Authors: Viana Jeandson Silva , de Oliveira José Fábio Ferreira , Gonçalves Edilma Pereira , Silva Monalisa Alves Diniz da , BORGES JOÃO PAULO GOES DA SILVA , Melo Luan Danilo Ferreira de Andrade , Silva Júlio César de Almeida , Lima Juliana Joice Pereira , Junior João Luciano de Andrade Melo 
Published: November 2023

Abstract
The use of techniques and products that maximize the production of a crop is fundamental when considering the scarcity of areas in regions that have adequate edaphoclimatic conditions for production or climatic inconsistency in other regions. Thus, the growth of national soybean production is due to research related to the theme; however, more studies can contribute to a greater productive advance in this segment. With this, the objective was to observe the influence of cutting times and the phytostimulant on the productivity of the soybean crop. Studies developed were in two agricultural years 2014/15 and 2015/16. The plot design was used, where the plots were formed by the cutting periods (40, 50, 60, 70 and 90 days after emergence (DAE) [1]and the subplots by the application of the phytostimulant (auxin, cytokinin and gibberellin), plus the witness without cutting. The Stimulate® positively (statistically higher) influenced analyzed variables; number of total pods (NVT), number of full pods (NVC), straw yield (RP), crop growth rate (TCC), harvest index (CI) and yield (GY). Cutting the aerial part of soybean plants at 40 DAE does not reduce grain production. Treatment of soybean seed with Stimulate® increases productivity at 15% and up to 60 DAE significantly stimulates soybean growth and regrowth.
The Efficacy of Preventing Portal Hypertension and Treating Cirrhosis Decompensation Due to Hepatitis B with Fuzheng Huayu Tablets, Entecavir and Carvedilol: study protocol for a multicenter randomized controlled trial
Authors: Guo Yanan , Li Zhengxin , Yangqing Ma , Huang Jihan , Lv Jing , Liu Chenghai 
Published: November 2023

Abstract
Background
Portal hypertension is an important pathological basis for the development of cirrhotic decompensation and its complications. The mechanism of its formation and development is complex, involving both increased intrahepatic resistance due to structural destruction of the liver and extrahepatic hyperdynamic circulation due to vasoactive substance disorders. However few drug has been provided values of primary prevention. Whether anti-liver fibrosis drugs would reduce the risk of portal hypertension was still not known.
Methods/design:
This is a non-blind, non-placebo-controlled, randomized, multicenter clinical trial. 192 chronic hepatitis B(CHB) patients with or without mild gastroesophageal varices in compensatory stage were enrolled for protocol A. Which the control group is given entecavir(ETV), and the experimental group is given Fuzheng Huayu Tablets(FZHY) and ETV. 184 CHB patients with moderate or severe gastroesophageal varices in compensatory stage were enrolled for protocol B. Which the control group is given ETV plus carvedilol(CDL), and the experimental group is given FZHY, ETV and CDL. Both protocols were carried out with 96w of treatment and 12w of follow-up. The primary outcome is the incidence of clinical event. The secondary outcome include: measurements of varicose veins, liver fibrosis and liver functions.
Discussion
This trial may carry out the effects of anti-liver fibrosis drugs(FZHY) on preventing portal hypertension or treating cirrhosis decompensation due to CHB.
Trial registration:
Clinical Trials.gov, ID: NCT 02945982. Registered on October 26, 2016.
Experimental Evaluation of Flexural and Bond Behaviours of Adobe Masonry
Authors: Rafi Muhammad Masood , Khan Sher , Marri Amanullah , Bhutto Muhammad Aslam 
Published: November 2023

Abstract

This paper presents the results of experimental testing of adobe masonry assemblages to study their flexure and bond behaviours. The properties of soil and water absorption of adobe units were also investigated. The plasticity index of the soil was 7.56 which was higher compared to that reported for the adobe soil in a few regions of the world. The silt and clay contents of the soil were also higher as compared to the soil used by the researchers elsewhere. High water absorption of the adobe units (27.37%) indicated their low cohesion characteristic which was evidenced by low bond strength. The flexure strength of the wallettes tested in a direction parallel to the bed joints was less as compared to those tested perpendicular to the bed joints. The tensile bond strength determined by the bond wrench method was considerably smaller as compared to the flexural strength of the wallettes. The observed flexural and bond strengths of the adobe masonry were also smaller as compared to those reported in the existing literature.
From Leaf to Soil: Exploring the Dynamics of Leaf Litter Production and Decomposition in a Sal Forest Ecosystems in Jharkhand, India
Authors: ANANDITA KUMARI , Sinha Anand Kumar , Jeganathan C 
Published: November 2023

Abstract

Understanding the complex processes of leaf litter production and decomposition is essential for understanding the nutrient cycle and ecosystem functioning in various terrestrial settings. The dynamics of leaf litter in Sal (Shorea robusta) forest ecosystems are investigated in this work. With comprehensive field sampling, quantification of the changes in leaf litter and pinpointing the underlying causes of these variances. This year-long study delved into the dynamics of litter in the Sal Forest across seven distinct locations. Results aligned with prior findings, emphasizing the role of Sal tree phenology and local climate, particularly temperature, in litter production dynamics. Sample point 6, inside a dense forest, stood out with abundant vegetation and diverse species, exhibiting optimal litter decomposition, nutrient accumulation, and utilization due to favorable temperature and humidity with a decay constant of 0.5358. May, June, and July fostered the highest decomposition, with a total mass loss of ~ 84.68%. Principle composite correlation value of soil factors such as pH (0.812), water holding capacity (0.924), moisture content (0.944), soil organic carbon (0.772), soil carbon (0.893), soil nitrogen (0.857), soil phosphorous (0.847), and soil potassium (0.726) and humidity (0.836) suggests that these factors significantly influence decomposition. The research underscores the intricate nature of litter decomposition, shaped by Sal tree phenology, climate, vegetation cover, and soil properties, collectively driving the Sal Forest ecosystem's ecological processes. This study provides a thorough picture of the transit of leaf litter from the forest canopy to the forest floor to comprehend the intricate links between leaf litter production and soil health in Sal Forest ecosystems.
Polariton Bose–Einstein Condensate from Bound State in the Continuum at Room Temperature
Authors: Liu Xinfeng , Wu Xianxin , Zhang Shuai , Song Jiepeng , Deng Xinyi , Du Wenna , Zeng Xin , Zhang Zhiyong , Chen Yuzhong , Wang Yubin , Jiang Chuanxiu , Zhong Yangguang , Wu Bo , Zhu Zhuoya , Liang Yin , Zhang Qing , Xiong Qihua 
Published: November 2023

Abstract
Exciton–polaritons (polaritons) resulting from the strong exciton–photon interaction stimulates the development of novel low-threshold coherent light sources to circumvent the ever-increasing energy demands of optical communications1-3. Polaritons from bound states in the continuum (BICs) are promising for Bose–Einstein condensation owing to their theoretically infinite quality factors, which provide prolonged lifetimes and benefit the polariton accumulations4-7. However, BIC polariton condensation remains limited to cryogenic temperatures ascribed to the small exciton binding energies of conventional material platforms. Herein, we demonstrated room-temperature BIC polariton condensation in perovskite photonic crystal lattices. BIC polariton condensation was demonstrated at the vicinity of the saddle point of polariton dispersion that generates directional vortex beam emission with long-range coherence. We also explore the peculiar switching effect among the miniaturized BIC polariton modes through effective polariton−polariton scattering. Our work paves the way for the practical implementation of BIC polariton condensates for integrated photonic and topological circuits.
Age-dependent loss of Crls1 causes myopathy and skeletal muscle regeneration failure
Authors: Seo Young Kyo , Yoo Youngbum , Yeon MyeongHoon , Kim Won-Kyung , Shin Hyeon-Bin , Lee Seung-Min , Yoon Mee-Sup , Ro Hyunju 
Published: November 2023

Abstract
Skeletal muscle aging results in the gradual deterioration of myogenesis, leading to muscle mass loss. However, the precise role of cardiolipin in myogenesis remains unclear. This study investigated the crucial role of mitochondrial cardiolipin and cardiolipin synthase 1 (Crls1) in age-related muscle deterioration and myogenesis. Our findings demonstrate that both cardiolipin and Crls1 are downregulated in aged skeletal muscles. Moreover, the knockdown of Crls1 in myoblasts resulted in reduced mitochondrial mass, activity, and expression of OXPHOS complex IV, along with the destruction of the mitochondrial cristae structure. AAV9-shCrls1-mediated downregulation of Crls1 impaired regeneration in a mouse model of cardiotoxin (CTX)-induced muscle damage, whereas Crls1 overexpression using AAV9-mCrls1 improved regeneration in an aging animal model of CTX-induced damage. Overall, our results highlight that the age-dependent decrease in Crls1 expression contributes to muscle loss by diminishing mitochondrial quality in skeletal muscle myoblasts. These findings suggest that modulation of Crls1 expression holds promise as a therapeutic strategy for mitigating muscle deterioration associated with aging, offering potential avenues for developing interventions to improve overall muscle health and quality of life in the elderly.
Blockade of C5aR1 resets M1 via gut microbiota-mediated PFKM stabilization in a TLR5-dependent manner
Authors: Yang Jing , Zhao Jie , Yao Chen , Qin Yongqin , Zhu Hanyong , Guo Hui , Ji Binbin , Li Xueqin , Sun Na , Li Rongqing , Wu Yuzhang , Zheng Kui-Yang , Pan Yuchen , Zhao Tingting 
Published: November 2023

Abstract
Background: Targeting C5aR1 modulates the function of infiltrated immune cells including tumor-associated macrophages (TAMs). The gut microbiome plays a pivotal role in colorectal cancer (CRC) tumorigenesis and development through TAM education. However, whether and how the gut flora is involved in C5aR1 inhibition-mediated TAMs remains unclear.
Methods: Genetic deletion C5ar1 or pharmacological inhibition of C5aR1 using anti-C5aR1 antibodies or PMX-53, in the presence or absence of deletion antibodies, were employed to investigate the impact and mechanism by which C5aR1 inhibition regulates polarization of tumor-associated macrophages through modulation of gut microbiota composition. The effects of C5aR1 inhibition in tumor growth were evaluated in MC-38 tumor bearing mice treated with or without the indicated compounds. The infiltrated immune cells and the polarization of TAMs was measured by flow cytometry. The glycolysis was examined by metabolic assays. Microarray analysis was utilized to assess the gene profiling. The levels of key enzymes in glycolysis were determined by Western blotting and quantitative PCR. The composition of gut microbiota was investigated using bacterial 16S rRNA sequencing. The relative expression of C5aR1 in TAMs from CRC patients was assessed using single-cell RNA-seq data from SCDVA and multiplexed immunofluorescence staining, respectively.
Results: C5aR1 inhibition elevated the concentration of serum IL-22 and the mRNA levels of its downstream target genes encoded antimicrobial peptides (AMPs), leading to gut microbiota modulation and flagellin releasement, which contributed to M1 polarization. In addition, our data revealed that high levels of C5aR1 in TAMs predicted poor prognosis.
Conclusion: C5aR1 inhibition reduced CRC growth via resetting M1 by AKT2 activation-mediated PFKM stabilization in a TLR5-dependent manner, which relied on IL-22-regulated gut flora.
Using Planar Biaxial Testing to Characterize the Changes in Axial Load and Strain of Human, Porcine, and Ovine Fossa Ovalis Following a Transseptal Puncture
Authors: Iaizzo Paul A , Vergen Jorge A , Ziph Josh , Lindberg Mary Elizabeth 
Published: November 2023

Abstract
Background
In many cardiovascular interventional procedures, transseptal punctures are used to gain access to the left atrial and ventricular anatomies. As various types of transseptal procedures (TSP) continue to be developed and improved, the fossa ovalis (FO), within the human hearts and pre-clinical models, still needs to be biomechanically studied. For example, the induced changes in FO properties following a transseptal procedure, are not fully understood. The goal of this study was to quantify changes in the biomechanical properties of human, porcine, and ovine FO before and after a TSP.
Methods
Physiologically viable human FO were recovered from non-transplantable human hearts. FO were also recovered from porcine and ovine hearts immediately after slaughter. Recovered FO were then measured using microcomputed tomography (µCT) and biomechanically assessed using planar biaxial testing. A proprietary instrument was then used to puncture the FO. Changes were then measured using planar biaxial testing.
Results
A total of five human FO, four porcine FO, and three ovine FO were successfully recovered and tested for this study. Across all sample groups, planar biaxial testing shows increased axial strain following a TSP. Axial load was observed to decrease across all sample groups.
Conclusions
Our study used planar biaxial testing to measure the changes in biomechanical properties following a TSP. This includes data on changes in the maximum mean axial strain and maximum mean axial load of human, porcine, and ovine FO following TSP procedures. These findings provide important insights for medical device and procedural developers.
Analyzing river disruption factors and ecological flow in China's Liu River Basin amid environmental changes
Authors: Li Mingqian , Wang He , Gu Hongbiao , Chi Baoming 
Published: November 2023

Abstract
Water resources variability and availability in a basin affect river flows and sustain river ecosystems. Climate change and human activities disrupt runoff sequences, causing water environmental issues like river channel interruptions. Therefore, determining ecological flow in changing environments is challenging in hydrological research. Based on an analysis of long-term changes in hydrological and meteorological variables and interruption conditions in the semi-arid Liu River Basin (LRB), this study summarizes the controlling factors of river interruption at different temporal and spatial scales and proposes a framework to determine ecological flow under changing environments. Hydrological model and the monthly optimal probability distribution (MOPD) were used to determine the optimal ecological runoff of LBR. The results showed that from 1956 to 2017, precipitation and potential evapotranspiration in the basin showed no significant decreasing trend, but the streamflow significantly decreased, and the downstream interruption worsened, with an average annual interruption duration of 194 days at Xinmin Station from 1988 to 2017. The controlling factors of river interruption are: (1) soil and water conservation measures in the upstream significantly reduce the runoff capacity; (2) the operation mode of the controlling reservoir in the middle reaches changes from "all-year discharge" to "winter storage and spring release" to "combined storage and supply,” severing the hydraulic connection between upstream and downstream; and (3) siltation in the downstream river channel coupled with over-extraction of groundwater increases the seepage capacity of the river. The monthly ecological flow of Naodehai Reservoir was determined by considering the monthly seepage losses after reconstructing the natural runoff using the SWAT model and determining the optimal probability distribution function for monthly runoff. The findings are important for downstream LRB ecological restoration and for determining the ecological flow of other river basins in changing environments.
Introduction of CS/GP improves the self-healing and flame-retardant effect of ENR/PLA composites
Authors: You Pingfeng , zhang ping , Chen Pengfei , Xie Ruishi , Chen lin , Xiong Ying 
Published: November 2023

Abstract
With the rapid development of society, polymer materials are widely used in automotive, construction, and electronic components due to their excellent properties such as easy processing, cheap price, and corrosion resistance. However, most polymers, such as rubber and leather, suffer from poor mechanical properties, susceptibility to micro cracking and flammability. In this paper, an epoxidized natural rubber (ENR)/polylactic acid (PLA)/chitosan (CS)/guanidine phosphate (GP) composite with certain self-healing and flame-retardant properties was successfully prepared. The network structure is constructed by forming thermoplastic elastomers (TVPs) through ENR and PLA, and the amino groups on CS and GP can form hydrogen bonds with ENR. which improves the mechanical properties of ENR/PLA composites and gives the ENR/PLA/CS/GP composites excellent self-healing properties. Secondly, CS and GP can also form intumescent flame retardants to improve the flame-retardant properties of ENR/PLA composites. Among them, the ENR/PLA/CS2/GP4 composite can achieve 78% self-healing effect and 35.8% reduction in flame retardant heat release rate (HRR).