bluuebunny/crossref_metadata_2025_split huggingface dataset:
The impact of credit reforms on bank loans and firm leverage around the world
Authors: Gonenc Halit , Jansen Floris , Tinoco Mario Hernandez , Vulanovic Milos 
Published: January 2024

AbstractThis study examines how credit reforms impact commercial bank loans and nonfinancial firms' debt. Using two international samples for commercial banks and nonfinancial firms from 2004 to 2019, we find that global information‐sharing reforms encourage banks to increase corporate loans, thus improving firm debt financing, particularly in countries with weak creditor rights. Legal rights reforms significantly boost corporate bank loans in emerging countries and enhance firms' debt financing in developed countries. Our findings suggest credit reforms positively impact firms' financing; however, their effects on debt financing supply and demand vary by economic development level and the strength of creditor rights.
Staying connected after divorce: Adolescent child and nonresidential parent perspectives
Authors: Markham Melinda Stafford , DeGreeff Becky , Guyette Erin 
Published: January 2024

AbstractObjectiveThe purpose of this study was to investigate how nonresidential parents and adolescent children maintained their relationships and communicated with one another following parental divorce.BackgroundA substantial proportion of children whose parents have divorced live with one parent and have less contact with the other parent. It is important to understand nonresidential parent–child relationships and the role communication technology plays in relationship maintenance.MethodQualitative interviews were conducted with a total of 34 adolescent and nonresidential parent participants (10 nonresidential parent–child dyads and 14 individual participants) to understand how nonresidential parents and children maintain their relationship following parental divorce and how they use communication technology to stay connected from a distance. Thematic analysis techniques (Braun & Clarke, 2006) were used to analyze the data.ResultsThree common positive factors or “benefits” relating to nonresidential parent–adolescent relationship closeness emerged: planned physical visits, frequent communication using multiple communication methods, and same sex of parent and child. Factors that served as barriers that interfered with nonresidential parent–adolescent relationship closeness were identified: residential parent interference, perceived child disengagement or lack of interest, and child blocking methods of communication.ConclusionThe results of this study provide additional insight and understanding that will help positively influence nonresidential parent–child relationships.ImplicationsPractitioners can help nonresidential parents identify communication technologies they can use with their adolescents and ways of reducing existing communication barriers.
Modelling the potential for local management practices to offset climate change impacts on freshwater macroinvertebrate communities
Authors: Orr James A. , Bussi Gianbattista , Hughes Jocelyne M. R. , Whitehead Paul G. , Jackson Michelle C. 
Published: January 2024

Abstract

A robust understanding of the interactions between global and local anthropogenic stressors is crucial for ecosystem management in the Anthropocene. Manipulative experiments in the laboratory or in the field can be used to build knowledge about the physiological and ecological effects of stressors, but predicting the combined landscape‐scale effects of global stressors such as climate change, and local stressors such as land‐use change requires a different approach.

Here we used water quality and hydrology process‐based models of entire river catchments in combination with a large biomonitoring dataset to predict the responses of macroinvertebrate communities under different climate change and land‐use change scenarios. Using the River Thames in the U.K. as a model system, we predicted changes in water quality (temperature, flow, phosphorus [P], nitrogen, dissolved oxygen [DO]) and subsequent changes in macroinvertebrate communities for two climate change scenarios, individually and in combination with intensified agriculture and reduced P pollution (representing improved wastewater treatment).

Our models predicted that water‐quality changes associated with climate change may not influence total species richness, but that community composition will shift towards more pollution‐tolerant and common taxa based on responses of community indices and taxon‐specific responses. We also found that the negative impacts of climate change on water quality (e.g., increased P concentration, decreased DO concentration) accumulate through the catchment, but that local land‐use practices influencing P dynamics can modify this trend. Furthermore, although the intensified agriculture scenario was predicted to have minimal impacts on macroinvertebrate communities (a result potentially related to shifting baselines as the Thames is already heavily polluted), we found that reduced P pollution resulting from improved wastewater treatment was able to mostly offset the negative impacts of climate change on macroinvertebrate communities.

Our results demonstrate that using process‐based models to study networks of interacting stressors at a landscape scale can provide useful insights into the ecological impacts of anthropogenic global change, and adds support to the idea that management of local stressors has the potential to mitigate some of the impacts of climate change on ecosystems.
Exploring experiences of living with removable dentures—A scoping review of qualitative literature
Authors: Broomhead T , Baker SR , Martin N , McKenna G , El‐Dhuwaib B , Alavi A , Gibson B 
Published: January 2024

ObjectiveExamine the literature on the experiences of living with removable dentures (complete or partial) to identify any gaps and provide a map for future research.BackgroundIncreasing proportions of society are living partially dentate with some form of restoration, including removable dentures. Previous studies have reported on the location, materials and usage of these prostheses, along with effects on oral‐health‐related quality of life (OHRQoL). However, less is known about experiences with removable dentures from a patient‐centred perspective.MethodsA scoping review of the qualitative literature was undertaken using the framework of Arksey and O'Malley, updated by Levac et al. Literature searches were carried out using Medline and Web of Science. Papers were screened by title and abstract using inclusion and exclusion criteria. Remaining papers were read in full and excluded if they did not meet the required criteria. Nine papers were included in the final review.FindingsKey themes from these papers were: impact of tooth loss and living without teeth, and its impacts in relation to social position, appearance, confidence and function (chewing and speaking); social norms and tooth loss, including attitudes to tooth retention and treatment costs, and changes in intergenerational norms towards dentures; expectations of treatment, including patients being more involved in decision making, viewing the denture as a “gift” and dentures helping to achieve “an ideal”; living with a removable denture (complete or partial), including patient preparedness for a denture, adaptation and impacts on activities and participation; and the dentist‐patient relationship, including issues with information and communication, and differing priorities between patients and dentists.ConclusionLittle qualitative research exists on experiences of living with a removable denture. Existing literature demonstrates the importance of dispersed activities in differing social, spatial and temporal contexts when wearing removable dentures. Focusing on processes of positive adaptation to dentures and OHRQoL, rather than deficits, is also required to fully understand patients' experiences. Additionally, more complex technological advances may not always be in the best interest of every patient.
Mouse transient receptor potential melastatin 2 (TRPM2) isoform 7 attenuates full‐length mouse TRPM2 activity through reductions in its expression by targeting it to ER‐associated degradation
Authors: Yamamoto Shinichiro , Kiyatake Naoto , Kaneko Akihiro , Shimamura Masanao , Yoshida Takashi , Shimizu Shunichi 
Published: January 2024

AbstractTransient receptor potential melastatin 2 (TRPM2) assembles into tetramers to function as an oxidative stress‐sensitive Ca2+ channel at the surface membrane. Limited information is currently available on the 10 protein isoforms of mouse TRPM2 (mTRPM2) identified. This study investigated whether these isoforms function as Ca2+ channels and examined their effects on full‐length mTRPM2 activity using the HEK 293 cell exogenous expression system. Only full‐length mTRPM2, isoform 1 localized to the surface membrane and was activated by oxidative stress. Isoform 7 was clearly recognized by protein quality control systems and degraded by endoplasmic reticulum‐associated degradation after transmembrane proteolysis. In the co‐expression system, the activation and expression of full‐length mTRPM2 were attenuated by its co‐expression with isoform 7, but not with the other isoforms. This decrease in the expression of full‐length mTRPM2 was recovered by the proteasomal inhibitor. The present results suggest that isoforms other than isoform 1 did not function as oxidative stress‐sensitive channels and also that only isoform 7 attenuated the activation of full‐length mTRPM2 by targeting it to endoplasmic reticulum‐associated degradation. The present study will provide important information on the functional nature of mTRPM2 isoforms for the elucidation of their roles in physiological and patho‐physiological responses in vivo using mouse models.
Can increased support to foster care families reduce the number of moves for children in out‐of‐home care? Evidence from Norway
Authors: Hornset Norunn , Smedsvik Bård 
Published: January 2024

AbstractNorwegian youth in out‐of‐home care move three times as frequently as their peers. Such placement instability is linked to negative outcomes in terms of social attachment, well‐being, educational achievements, health, and future opportunities. Norway implemented a new child welfare service reform in 2022 that increased the municipalities responsibilities for out‐of‐home care. The “incentive package” and “Barneløftet” were measures implemented to prepare the municipalities for these changes. This study evaluates how the implemented measures affect the number of moves within out‐of‐home care in Trøndelag county. An event‐study design with difference‐in‐difference estimates was used to study the effect of the measures. The data are Norwegian registers that include most children in out‐of‐home care from 2013 to 2021. The findings of this study indicate that increased support for foster care homes significantly reduces the number of moves. Increased placement stability is associated with an increased sense of belonging, thus facilitating positive development.
The hAT family hopper transposon exists as highly similar yet discontinuous elements in the Bactrocera tephritid fly genus
Authors: Handler Alfred M. , Furlong Richard B. 
Published: January 2024

AbstractThe hAT family transposable element, hopper, was originally discovered as a defective 3120‐bp full‐length element in a wild‐type strain of the oriental fruit fly, Bactrocera dorsalis (Hendel) (Diptera: Tephritidae), and subsequently a functional 3131‐bp element, hopperBdwe, was isolated from a white eye mutant strain. The latter study showed that closely related elements exist in melonfly, Zeugodacus cucurbitae (Coquillett) (Diptera: Tephritidae), a closely related subgenus, suggesting that hopper could have a widespread presence in the Bactrocera genus. To further understand the distribution of hopper within and beyond the B. dorsalis species complex, primer pairs from hopperBdwe and its adjacent genomic insertion site were used to survey the presence and relatedness of hopper in five species within the complex and four species beyond the complex. Based on sequence identity of a 1.94 kb internal nucleotide sequence, the closest relationships were with mutated elements from B. dorsalis s.s. and species synonymized with B. dorsalis including B. papayae, B. philippinensis and B. invadens, ranging in identity between 88.4% and 99.5%. Notably, Bactrocera carambolae (Drew & Hancock) (Diptera: Tephritidae), which is most closely related to B. dorsalis beyond the synonymized species, shared hopper identities of 97.3%–99.5%. Beyond the B. dorsalis complex, Z. cucurbitae, Bactrocera tryoni (Froggatt) (Diptera: Tephritidae) and Bactrocera zonata (Saunders) (Diptera: Tephritidae) shared identities of 83.1%–97.1%, while hopper was absent from the Bactrocera oleae (Gmelin) (Diptera: Tephritidae) strain tested. While the functional autonomous hopperBdwe element was not detected in these species, another closely related hopper element isolated from a B. dorsalis genetic sexing strain has an uninterrupted transposase open reading frame. The discontinuous presence of hopper in the Bactrocera genus has implications for its use for genomic manipulation and understanding the phylogenetic relationship of these species.
A 6‐year experience of Zephyr endobronchial valves for severe emphysema in an Australian single‐centre cohort
Authors: Brown Michael V. , Badiei Arash , Jersmann Hubertus , Fon Andrew , Chew Chong G. , Lorraine Brett , Nguyen Phan 
Published: January 2024

AbstractBackgroundEndobronchial valve (EBV) insertion for lung volume reduction is a management option for patients with severe emphysema. One‐way valves cause lobar deflation and improve lung function, exercise capacity and quality of life.AimsTo retrospectively analyse and compare the outcomes of the first 57 patients treated with EBVs between 2015 and 2021 at the Royal Adelaide Hospital to international standards.MethodsClinical outcomes of forced expiratory volume in 1 s (FEV1), residual volume (RV), treated lobe volume reduction (TLVR) and 6‐min walk distance (6MWD) at 3, 6 and 12 months after valve insertion were reviewed against established minimally clinically important differences (MCIDs). Complications and subjective breathlessness measured by Borg scores were also reviewed.ResultsFifty‐seven patients were included. At 12 months, 77.2% achieved TLVR. FEV1 improved by 170 mL (95% confidence interval (CI): 100–250, P < 0.001), 80 mL (95% CI: 10–150, P = 0.019) and 40 mL (95% CI: −60 to 130, P 0.66) at 3, 6 and 12 months respectively. RV improved by −610 mL (95% CI: −330 to −900, P < 0.0001) at 3 months, −640 mL (95% CI: −360 to −920, P < 0.0001) at 6 months and −360 mL (95% CI: −60 to −680, P = 0.017) at 12 months. 6MWD improved by 57.34 m (95% CI: 36.23–78.45, P < 0.0001) and 44.93 m (95% CI: 7.19–82.67, P = 0.02) at 3 and 6 months. Borg score improved by −0.53 (95% CI: 0.11 to −1.2, P = 0.11) and −0.49 (95% CI: 0.17 to −1.15, P = 0.16) at 3 and 6 months. Complication rates aligned with international standards with mucous/infection (26.3%) and pneumothorax (17.5%) as the most common. Subgroup analysis signalled improved outcomes in patients with heterogeneous emphysema.ConclusionOur study represents the first publicly funded Australian analysis of EBVs. The results align with international prospective trials demonstrating improved lung function and exercise capacity. Australians with severe emphysema and gas trapping should be referred to a multidisciplinary centre for consideration of EBVs.
Reliability comparisons between additively manufactured and conventional SiC–Si ceramic composites
Authors: Chaugule Pawan S. , Du Wenchao , Kamath Rakesh R. , Barua Bipul , Messner Mark C. , Singh Dileep 
Published: January 2024

AbstractAn additively manufactured reaction‐bonded silicon carbide ceramic composite is fabricated using a bimodal powder feedstock and the binder‐jetting printing technique. On fabricating, the ceramic is investigated to report its composition, mechanical, and thermal properties at room temperature and high temperatures (up to 750). The ceramic has a density of 2.76 g/cc, and shows a hardness of 21.74 GPa, and a flexure strength of 207.5 MPa at room temperature. The mechanical property of flexure strength is used to estimate its failure probability under applied stress, using a Weibull distribution. The mechanical properties and failure probabilities are compared with those of conventionally fabricated reaction‐bonded silicon carbide ceramics reported in the literature. These ceramics were fabricated using methods such as slip‐casting, compacting, and tape‐casting. The comparison is used to elucidate the advantages and areas of improvement of the present additive manufacturing technique for reaction‐bonded ceramics.
Genome‐wide detection of structural variation in some sheep breeds using whole‐genome long‐read sequencing data
Authors: Qiao Guoyan , Xu Pan , Guo Tingting , He Xue , Yue Yaojing , Yang Bohui 
Published: January 2024

AbstractGenomic structural variants (SVs) constitute a significant proportion of genetic variation in the genome. The rapid development of long‐reads sequencing has facilitated the detection of long‐fragment SVs. There is no published study to detect SVs using long‐read data from sheep. We applied a long‐read mapping approach to detect SVs and characterized a total of 30,771 insertions, deletions, inversions and translocations. We identified 716, 916, 842 and 303 specific SVs in Southdown sheep, Alpine merino sheep, Qilian White Tibetan sheep and Oula sheep, respectively. We annotated these SVs and found that these SV‐related genes were primarily enriched in the well‐established pathways involved in the regulation of the immune system, growth and development and environmental adaptability. We detected and annotated SVs based on NGS resequencing data to validate the accuracy based on third‐generation detection. Moreover, five candidate SVs were verified using the PCR method in 50 sheep. Our study is the first to use a long‐reads sequencing approach to construct a novel structural variation map in sheep. We have completed a preliminary exploration of the potential effects of SVs on sheep.
Clinical outcomes and risk factor analysis of dental implants inserted with lateral maxillary sinus floor augmentation: A 3‐ to 8‐year retrospective study
Authors: Zhang Liefen , Zhou Chuan , Jiang Jimin , Chen Xiaoyu , Wang Yaoqiong , Xu Antian , He Fuming 
Published: January 2024

AbstractAimTo evaluate the 3‐ to 8‐year outcomes of dental implants placed with lateral sinus floor augmentation (LSFA) and to identify factors affecting implant survival.Materials and MethodsThis retrospective study was performed by screening all implants placed with LSFA procedures, which were conducted between January 2012 and December 2016. Subantral bone gain (SABG) and apical bone height (ABH) were assessed using panoramic radiographs. The cumulative survival rate of implants was analysed using life‐table analysis and Kaplan–Meier survival curves. The influential risk factors affecting survival were assessed using univariate log‐rank tests and multivariable mixture cure rate model. Implant complications were recorded.ResultsBased on the established criteria, a total of 449 patients (760 implants) were included in this study. In the 3‐ to 8‐year follow‐up (mean ± SD, 5.81 ± 1.33 years), 15 implants in 14 patients failed, with a CRS of 96.81% on an implant basis and 95.07% on a patient basis. A history of periodontitis and poor compliance with supportive periodontal treatment was associated with a significantly higher risk of implant failure at both implant and patient levels. Significant decreases in ABH occurred during each yearly interval except for 3 years. A similar trend has been observed for SABG at 1, 2, 6 and 8 years. The total complication rate was 31.84% on implant basis, with peri‐implant mucositis (21.58%) being the most frequent biologic complication and porcelain cracking (5.00%) being the most common technical complication.ConclusionsImplant with LSFA is a reliable treatment option in atrophic maxilla. A history of periodontitis without regular supportive periodontal treatment was identified as a predictor for implant failure. Slight but significant shrinkage of vertically augmented bone can be observed after implant placement.
Association between glycemia risk index and arterial stiffness in type 2 diabetes
Authors: Cai Lingli , Shen Wenqi , Li Jiang , Wang Bin , Sun Ying , Chen Yi , Gao Ling , Xu Fei , Xiao Xinhua , Wang Ningjian , Lu Yingli 
Published: January 2024

ABSTRACTAimThis study aims to investigate the association of glycemia risk index (GRI), a novel composite metric derived from continuous glucose monitoring (CGM), with arterial stiffness in patients with type 2 diabetes.Materials and MethodsA total of 342 adults with type 2 diabetes were enrolled between April and June 2023 from 11 communities in Shanghai, China. Medical examinations, including measurements of anthropometric parameters, blood pressure, and venous blood samples were conducted. Brachial‐ankle pulse wave velocity (baPWV) was examined to evaluate arterial stiffness. All the participants underwent a 14 day CGM recording and GRI was calculated from the CGM data.ResultsThe mean age was 70.3 ± 6.8 years, and 162 (47.4%) were male. Participants with a higher baPWV had significantly higher levels of GRI and hyperglycemia component (both P for trend < 0.05). Linear regression revealed the significant positive linear associations of the GRI with baPWV in unadjusted or adjusted models (All P < 0.05). In the multivariable logistic analysis, each increase in the GRI quartile was associated with a 1.30‐fold (95% CI 1.01–1.68, P for trend < 0.05) higher prevalence of increased arterial stiffness after adjustment for age, sex, BMI, diabetes duration, current smoking status, blood pressure, and lipid profile. Subgroup analyses showed that the association between the GRI quartiles and increased arterial stiffness was stronger among participants with a diabetes duration ≥15 years (P for interaction = 0.014).ConclusionGlycemia risk index assessed by continuous glucose monitoring is associated with increased arterial stiffness in type 2 diabetes.
Staged esthetic crown lengthening: Classification and guidelines for periodontal‐restorative therapy
Authors: Lee Ernesto A. , Cambra Victor , Bergler Michael 
Published: January 2024

AbstractObjectiveThis article presents technical guidelines for perio‐restorative esthetic crown lengthening, along with a discussion of the biologic rationale. A classification system is proposed to assist in treatment planning and sequencing the surgical and restorative phases.Clinical ConsiderationsWhen esthetic crown lengthening is performed as an adjunct to restorative therapy, the surgical approach must be determined by the anticipated position of the restorative margins. The removal of sufficient bone to achieve the desired clinical crown length and preserve the supracrestal gingival tissue dimensions is facilitated by the use of a surgical guide fabricated according to the design of the restorations. A staged approach allows sequencing the provisional restoration to minimize unesthetic sequelae during the healing period. Inadequate bone resection and/or alteration of the soft tissue dimensions results in delayed healing, leading to coronal gingival rebound and biologic width impingement.ConclusionThe identification and preservation of appropriate restorative and biologic landmarks is essential for success in pre‐prosthetic esthetic crown lengthening treatment. A staged approach improves the esthetic management during the postsurgical healing and maturation period.Clinical SignificanceA restorative driven classification system for sequencing and staging adjunctive esthetic crown lengthening procedures is presented. Technical guidelines to enhance gingival margin predictability are suggested, accompanied by relevant evidence. In addition, wound healing timelines following gingival and osseous resection are provided.