bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perspectives of Healthcare Professionals on the use of Immersive Virtual Reality in Teenage and Young Adult Oncology: A Qualitative Interview Study
Authors: Deighan Mairi , Simpson Daniel , Brigden Amberly , Cater Kirsten 
Published: December 2023

Abstract

Background: Applications of Virtual Reality (VR) in healthcare continue to grow at a rapid pace, yet the challenges and opportunities associated with VR from the perspective of clinicians and healthcare staff remain underexplored, particularly in the context of Teenage and Young Adult (TYA) oncology. This study aims to bridge this knowledge gap by interviewing clinicians and staff regarding the use of VR in TYA cancer care.
Method: Fourteen semi-structured qualitative interviews were conducted with a diverse range of healthcare professionals working in TYA oncology within the United Kingdom including oncologists, hematologists, clinical nurse specialists, clinical psychologists, radiographers, play specialists, clinical social workers and youth support coordinators. Data were analysed thematically with three themes and seven sub-themes developed.
Results: The findings reveal that TYA healthcare professionals are optimistic and enthusiastic about the potential of using VR to enhance cancer care for teenagers and young adults. However, they also expressed notable concerns related to the practical implementation of VR in clinical settings. These concerns included infection and safety risks, privacy and security concerns, cost implications, storage requirements and staff burden. Clinicians and staff proposed valuable applications for VR in TYA oncology specifically in patient distraction, physiotherapy, procedure preparation, and the delivery of psychotherapy, including acceptance and commitment therapy.
Conclusions: This research has demonstrated that despite an enthusiasm to adopt VR in TYA oncology there are still many challenges, both practical and ethical, that must be addressed to enable the successful implementation of VR in hospitals within the UK. Further research into applications of VR for TYA oncology is warranted, particularly in areas of psychology, physiotherapy, and procedure preparation.
HyperGCN - A Multi-layer Graph NeuralNetworks to Enhance Hyperspectral Image Classification
Authors: P Haseena Rahmath , Srivast Vishal , Chaurasia Kuldeep 
Published: December 2023

Abstract
Graph neural networks (GNNs) have recently attracted much attention due totheir exceptional performance in a wide range of applications, including hyperspectralimage classification. However, most GNN-based models developed forhyperspectral image classification are shallow-layer models that combine CNNand GNN to improve performance. The use of fewer layers in their GNN models isattributed to the observed degradation in performance as the depth of GNN modelsincreases. This study proposes HyperGCN, an exclusive GNN-based modelwith multiple graph convolutional layers that exploit the rich spectral informationcontained in hyperspectral images and improve classification performance.HyperGCN prevents performance degradation by incorporating over-smoothingresistanttechniques into its architecture. Extensive experiments on widely usedhyperspectral benchmark datasets such as the Indian Pines dataset and thePavia University dataset show that HyperGCN outperforms traditional graphconvolutional neural network models in all performance metrics, including overallaccuracy, average accuracy, class-specific accuracy, and Cohen’s kappa coefficient.HyperGCN also outperformed fusion models that combine the benefits of CNNand GNN when classifying hyperspectral images.
Allogeneic haematopoietic stem cell transplantation might overcome the poor prognosis of adult T-lineage acute lymphoblastic leukaemia with CDKN2 deletion
Authors: Liu Qifa , Hu Xiaoshan , Wang ZhiXiang , Qin Yuting , Xu Jun , Xu Na , Wang Qiang , Lin Ren , Zhao Ke , Zhou Hongsheng , Xuan Li , Yu Sijian 
Published: December 2023

Abstract
The clinical significance of cyclin-dependent kinase inhibitor 2 (CDKN2) deletion in adult T-lineage acute lymphoblastic leukemia (T-ALL) is still a matter of debate. This study aimed to investigate the prognostic value of CDKN2 deletion and impact of allogeneic hematopoietic stem cell transplantation (allo-HSCT) in adult T-ALL. A total of 241 T-ALL patients were enrolled in this single-center retrospective study: 57 with CDKN2 deletion and 184 with CDKN2 wild-type (WT). CDKN2 deletion was associated with a higher white blood cell (WBC) count (P = 0.013), a greater proportion of high-risk disease (P = 0.004), and a complex karyotype (P = 0.004) than CDKN2 WT. The 5-year cumulative incidence of relapse (CIR) was 30.9% (95% CI 17.5-45.3) and 17.5% (95% CI 11.2-25.1) (P = 0.004), disease-free survival (DFS) was 39.7% (95% CI 25.6-53.4) and 53.8% (95% CI 45.1-61.7) (P = 0.002), and overall survival (OS) was 36.8% (95% CI 23.2-50.5) and 58.2% (95% CI 49.1-66.2) (P < 0.001) in patients with CDKN2 deletion and CDKN2 WT, respectively. In the multivariable analysis of the entire population, CDKN2 deletion was found to be an independent adverse prognostic factor for CIR (HR 2.79 (95% CI 1.3-6), P = 0.009), DFS (HR 1.76 (95% CI 1.1-2.79), P = 0.018), and OS (HR 1.91 (95% CI 1.19-3.07), P = 0.008). In the CDKN2 deletion subgroup, the 5-year CIR was 15.8% (95% CI 4.8-32.6) and 53.9% (95% CI 26.3-75.1) (P = 0.005), DFS was 51.8% (95% CI 30.9-69.1) and 21.1% (95% CI 7.2-39.8) (P < 0.001), and OS was 51.2% (95% CI 30.4-68.7) and 17.4% (95% CI 4.8-36.5) (P < 0.001) in patients with and without allo-HSCT, respectively.
Conclusion: CDKN2 deletion is associated with poor prognosis in adult patients with T-ALL. Patients with T-ALL and CDKN2 deletions may benefit from allo-HSCT.
Associations of Meaning of Home and Housing-Related Control Beliefs with Changes in Symptoms and Quality of Life: A Prospective Study Among Younger-Old Adults in Sweden
Authors: Eriksson Erik , Kylén Maya , Ekström Henrik , Slaug Björn , Elmståhl Sölve , Iwarsson Susanne , Schmidt Steven 
Published: December 2023

Abstract
Feeling in control of one’s environment, and perceiving one’s home as meaningful, have been found to be associated with health and wellbeing among older adults. As longitudinal studies of younger-old adults are lacking, this study aimed to investigate whether this association exists over time among older adults around retirement age. This study used longitudinal data from a random cohort of older adults in southern Sweden collected over a period of around 6 years (~2010-2016). In total, 329 community dwelling older adults, ages 65-76 (190 women and 139 men) participated in the study. Meaningfulness of one’s home was assessed by the Meaning of Home questionnaire, feelings of control of one’s home environment by the Housing-Related Control Beliefs questionnaire, symptom severity by a symptom checklist, and quality of life by Short-Form 12. Analyses was performed by stepwise General Linear Regression models. Housing-Related Control Beliefs was not significantly associated with changes in quality of life. Meaning of Home was found to be significantly associated with changes in gastrointestinal (B= 0.039, p= 0.031) and metabolism (B= 0.084, p< 0.000) symptoms. However, there were inconsistencies among the subscales of the instrument as some were negatively associated, and others were positively associated, with the change. The overall findings therefore suggest that the perceived home environment does not have a significant role in preventing symptoms, or in maintaining or improving quality of life, among older adults around retirement age. This finding is of importance to further develop theoretical understandings of the environments’ role in healthy ageing.
Complexity in Bolza Surface
Authors: Saha Bhola Nath , Sanki Bidyut 
Published: December 2023

Abstract
A surface in the Teichmüller space, where the systole function attains its maximum, is called a maximal surface. For genus two there exists a unique maximal surface which is called the Bolza surface. In this article, we study the complexity of the set of systolic geodesics on the Bolza surface. We show that any non-systolic geodesic intersects the systolic geodesics in 2n points, where n ≥ 5. Furthermore, we show that there are 12 second systolic geodesics on the Bolza surface and they form a triangulation of the surface.
Prevalence of breast cancer in rural population of Jaipur: A survey-based observational study
Authors: Singh Roshni , Kumar Sachin , Nakash Prashant , Kumar Ramesh , Kumar Govind , pal Pusparghya , Mishra Shivang , Raj Preeti , Rajotiya Sumit , Singh Anurag Kumar , Debnath Sourav , Chaturvedi Bhumi , Bareth Hemant , Patel Akhilesh , Singh Mahaveer , Srivast Anurag , Nathiya Deepak , Tomar Balvir Singh 
Published: December 2023

Abstract
Background
Breast cancer, a global health concern predominantly affecting women, recorded 2.3 million new cases and 685,000 deaths in 2020. Alarmingly, projections suggest that by 2040, there could be over 3 million new cases and 1 million deaths.
Objectives
To assess breast cancer prevalence in 24 rural villages within a 60 km radius of NIMS Hospital, Tala Mod, Jaipur, Rajasthan, North India 303121.
Materials and Methods
A study involving 2023 participants conducted initial screenings, and positive cases underwent further tests, including ultrasound, mammography, and biopsy. SPSSv28 analysed collected data.
Results
Among 2023 subjects, 3 screened positive for breast lumps. Subsequent clinical examination and biopsy identified 1 normal case and 2 with breast cancer, resulting in a prevalence proportion of 0.0009 or 98 per 100,000.
Conclusion
This study helps fill gap in breast cancer prevalence data for rural Rajasthan. The results highlight a concerning prevalence of breast cancer in the rural area near NIMS hospital, emphasizing the urgent need for increased awareness, early detection, and better healthcare access. Challenges like limited resources, awareness programs, and delayed diagnosis contribute to this high incidence. To address this, comprehensive approach is necessary, including improved screening programs and healthcare facilities in rural areas. Prioritizing rural healthcare and evidence-based strategies can reduce the burden of breast cancer and improve health outcomes.
Global Financial Investment Connectedness, ICT, and Intellectual Property Strategy: A Country-Level Empirical Analysis
Authors: Yoo Sungjin 
Published: December 2023

Abstract
This study investigated the direct and indirect impacts of financial investment connectedness and Information and Communication Technology (ICT) on countries’ Intellectual Property (IP) strategies. By utilizing the panel logit model on the longitudinal country-level data, we found that countries’ positions in the global financial investment network significantly affect their IP strategies. Furthermore, ICT usage weakens the IP strategy’s reliance on global financial investment connectedness. This study is among the first to link financial investment connectedness and ICT to intellectual property strategy. Implications for governments to manage financial investment portfolios as well as make intellectual property strategies are derived.
Development of an Effective Sentiment Classification Architecture for Texts Containing Negation Words and Emojis
Authors: Bonga Favour Kefas , Varshney Pooja 
Published: December 2023

Abstract
The widespread use of social media platforms like Facebook, Instagram, Reddit, and Twitter has profoundly influenced human interactions and decision-making. Twitter, in particular, has become a popular platform for sharing opinions on diverse topics, resulting in a substantial volume of user-generated content known as tweets. Emojis, which convey emotions and moods, have become integral to online communication. However, existing sentiment analysis methods struggle with the unique characteristics of tweets, such as negation words, contracted phrases, shortened text, language ambiguities, and emojis. To address these challenges, a novel word representational framework is proposed in this research, considering both negation words and emojis. Sentiment analysis is performed using Long Short-Term Memory (LSTM) neural networks to capture both syntactic and semantic features of tweets, enhancing sentiment classification efficiency. Extensive experiments on three benchmark datasets validate the approach, resulting in impressive accuracy rates of 95.24%, 87.13%, and 94.18% on different datasets. These results underscore the effectiveness of the proposed method in handling the complexities of sentiment analysis in the context of tweets, with applications in business insights, government policy formulation, decision-making processes, and brand identity monitoring.
Can audit firms be trusted (again)?
Authors: Beretta Valentina , Demartini Maria Chiara , Trucco Sara 
Published: December 2023

Abstract
Accounting research demonstrated that financial audit can hardly be conceived of as a trust engendering technology yet. According to the sociological theory of trust, trust in auditors is divided into first order and second order trust. First order trust aims at identifying the factors that primarily contribute to the auditor’s trustworthiness, whereas second order trust mirrors the capability of the trust on auditors to be transferred to their clients.
In order to gauge if audit can be trusted again and to analyze if trust can be transferred and how, this study investigates the current audit industry through the lens of the sociological theory of trust.
Results from a panel data analysis show that audit professionalism, commercial orientation and market concentration are the main determinants of first order trust. Moreover, findings from this study highlight that an audit firm’s trustworthiness is negatively transferred to its client.
This study adds knowledge to the theory of trust developed by Sztompka, by providing evidence of which factors impact on the primary object of trust, and how it is possible to transfer them on the secondary object of trust. Indeed, empirical evidence supports that part of literature arguing that auditing is primarily aimed at reproducing social order, whereas limited support is found to the trust engendering role of financial audit.
Occurrence and diversity of nontuberculous mycobacteria affected by water stagnation in building plumbing
Authors: Rahmatika Iftita , Simazaki Dai , Kurisu Futoshi , Furumai Hiroaki , Kasuga Ikuro 
Published: December 2023

Abstract

Nontuberculous mycobacteria (NTM) refer to mycobacteria other than Mycobacterium tuberculosis and Mycobacterium leprae. Some NTM are known to cause pulmonary and skin diseases. As NTM are prevalent in water supply systems, the health burden of waterborne NTM is concerned. However, little is known about NTM in building plumbing. This study revealed the abundance and diversity of NTM in building plumbing by using culture-dependent and culture-independent approaches. Moreover, the chlorine susceptibility of NTM isolates in tap water was evaluated. The increase in the abundance of Mycobacterium spp. was observed in some taps after 24 h of stagnation, indicating that NTM could have the potential to regrow in building plumbing. While Mycobacterium mucogenicum and Mycobacterium avium were detected by cultivation, amplicon sequencing of NTM-specific hsp65 genes revealed that Mycobacterium gordonae was dominant in most of the samples, which was not detected by cultivation. The chlorine susceptibility experiment demonstrated that NTM strains related to M. avium and M. mucogenicum were 119 and 426 times more tolerant to chlorine than Escherichia coli, respectively. As M. mucogenicum, M. avium, and M. gordonae are regarded as opportunistic pathogens, intensive monitoring of NTM in tap water in building plumbing is necessary.
Classification and description of the drainage state of manholes in urban drainage systems
Authors: Zhang Dawei , Han Dixi , Zhong Qiang , Chen Qigang 
Published: December 2023

Abstract

Manholes are important structures in urban storm drainage systems connecting roads and underground drainage networks, and they are also an important part of the research on improving urban resistance to storm flooding. Due to cost and space constraints, most of the existing experimental data on manholes come from scale model experiments obtained by scaling according to Froude's similarity criterion, and there is a lack of validation based on full-size experimental data. This also leads to inconsistencies in the form and parameter values of the manhole flow exchange equations derived from different experiments. To remedy this deficiency, a full-scale urban drainage engineering physics model was developed in this study with the aim of investigating the flow exchange of surface water as it flows through manholes into the sewer system. Experiments were conducted under steady flow conditions and compared with predictions from the existing models. The results show that the predictions of the existing model deviate significantly from the measured values when the flow is between free weir flow and submerged orifice flow. Therefore, we constructed a weighting equation based on weir and orifice flows and found that the weighting coefficients decayed exponentially during the transition from weir to orifice flow.
Hubungan antara Anonimitas dan Moral Disengagement dengan Perilaku Cyberbullying pada Penggemar K-Pop yang Melakukan Fanwar
Authors: Khoiriyah Erfira , Pramono Ridwan Budi 
Published: December 2023

This study is a quantitative study that aims to determine the relationship between anonymity and moral disengagement with cyberbullying behavior in K-Pop fans who do fanwar. Purposive sampling was used in sampling so that 250 K-Pop fans filled out the cyberbullying scale, anonymity scale, and moral disengagement scale. The results of the analysis show that there is a relationship between anonymity and moral disengagement with cyberbullying behavior in K-pop fans who do fanwar with a correlation coefficient of 0.413 and a p value 0.001 (p 0.01) and an effective contribution of 17%. Anonymity is positively and significantly related to cyberbullying as indicated by a correlation coefficient of 0.271 and a p value of 0.001 (p 0.01). Moral disengagement is positively and significantly related to cyberbullying as indicated by a correlation coefficient of 0.398 and a p value of 0.001 (p 0.01). The results indicate that anonymity and moral disengagement can increase individual participation in cyberbullying behavior. Structural Equation Modeling (SEM) analysis was conducted to assess the strength of aspects. The aspect of "Imbalance Power" in measuring cyberbullying, the aspect of "Lack of Identification" in measuring anonymity, and the aspect of "Moral Justification" in measuring moral disengagement have low loading factors, thus proving less effective in measurement in this research. Penelitian ini merupakan penelitian kuantitatif yang bertujuan untuk mengetahui hubungan antara anonimitas dan moral disengagement dengan perilaku cyberbullying pada penggemar K-Pop yang melakukan fanwar. Purposive sampling digunakan dalam pengambilan sampel sehingga 250 penggemar K-Pop mengisi skala skala cyberbullying, skala anonimitas, dan skala moral disengagement. Hasil analisis menunjukkan bahwa terdapat hubungan anonimitas dan moral disengagement dengan perilaku cyberbullying pada penggemar K-pop yang melakukan fanwar dengan koefisien korelasi 0.413 dan nilai p 0.001 (p 0.01) serta sumbangan efektif sebesar 17%. Anonimitas berhubungan positif yang sangat signifikan dengan cyberbullying ditunjukkan dengan koefisien korelasi 0.271 dan nilai p 0.001 (p 0.01). Moral disengagement berhubungan positif yang sangat signifikan dengan cyberbullying ditunjukkan dengan koefisien korelasi 0.398 dan nilai p 0.001 (p 0.01). Hasil penelitian menunjukkan bahwa anonimitas dan moral disengagement dapat meningkatkan partisipasi individu dalam perilaku cyberbullying. Analisis Structural Equation Modeling (SEM) dilakukan untuk mengukur kekuatan aspek. Aspek “Ketidakseimbangan Kekuatan” dalam mengukur cyberbullying. Aspek “Kurangnya Identifikasi” dalam mengukur anonimitas, dan Aspek “Justifikasi Moral” dalam mengukur moral disengagement memiliki loading factor yang rendah sehingga kurang efektif melakukan pengukuran dalam penelitian ini.
Catalytic Combustion of Acrylonitrile over CuCeOx-HBETA Catalysts
Authors: Bueno Romero Torres , Da Mata João Emanuel Cabral , Urquieta-González Ernesto Antônio , Batista Marcelo da Silva 
Published: December 2023

Purpose: Evaluate the acrylonitrile combustion using copper and cerium catalysts supported on BETA zeolite (CuCeOx-HBETA), aiming to reduce the emission of this pollutant in industrial exhaust gases.

Theoretical framework: Acrylonitrile (ACN) is one of the most used monomers in the chemical industry. However, it is a volatile organic compound (VOC) of high toxicity, being present in the exhaust gases of its own production process. In this context, selective catalytic combustion (SCC) stands as a highly promising technology for the removal of ACN in industrial gas effluents.

Method: CuCeOx-HBETA catalysts were prepared by wet impregnation. For characterize the catalysts, the techniques of X-ray diffractometry (XRD), Fourier transform infrared spectroscopy (FTIR) and reduction with hydrogen at programmed temperature (TPR-H2) were used. Catalytic tests were carried out on ACN combustion by varying the reaction temperature.

Results and conclusion: The characterization results showed that copper and/or cerium oxides are present in the catalysts as nanoparticles. The addition of CeO2 improved the dispersion and facilitated the reducibility of CuO. The CuCeOx-HBETA catalysts achieved high ACN conversions at temperatures (300-350°C) much lower than traditional thermal combustion (T > 900°C). The greater activity of the catalysts can be attributed to the presence of highly dispersed CuO species and isolated Cu2+ ions. The 10Cu10Ce-HBETA catalyst, with a copper/cerium ratio equal to 1, was the most active due to the best synergy between copper and cerium species.

Research implications: The research indicates great potential for the use of CuCeOx-HBETA catalysts in the combustion of ACN.

Originality/value: This study brings new contributions to the research of catalysts to be applied in the catalytic combustion of nitrile compounds.
Changes in the amino acid pool in the rat parietal lobe and hippocampus with incomplete cerebral ischemia
Authors: Bon E. I. , Maksimovich N. Ye. , Doroshenko E. M. , Smirnov V. Yu. , Danilevich M. A. , Golushko A. S. 
Published: December 2023

Introduction. Amino acids and their derivatives are involved in synaptic transmission as neurotransmitters and neuromodulators, and some of them are involved in the formation of neurotransmitters of the nervous system. Therefore, the study of the state of the amino acid pool in incomplete cerebral ischemia plays a significant role.The objective was to assess the nature of changes in amino acid pool and evaluate their participation in oxidative processes in rats with incomplete cerebral ischemia.Methods and materials. The experiments were carried out on 16 male outbred white rats weighing 260±20 g in compliance with the requirements of the Directive of the European Parliament and of the Council No. 2010/63/EU of September 22, 2010 on the protection of animals used for scientific purposes.Results. Compared with the indicators in the control group, rats with an ischemic period of 1 hour in the parietal lobe had a decrease in the content of sulfur-containing amino acids: methionine by 12 % and cysteate by 28 %. In addition, there was an increase of L-arginine in the parietal lobe by 39 %, and in the hippocampus – by 56 %.Conclusions. The following changes are characteristic for one-hour incomplete cerebral ischemia: a decrease in the content of sulfur-containing amino acids, with a decrease in both methionine and an increase in the content of L-arginine. Changes in the parietal lobe and hippocampus had a similar nature, except for the absence of a drop in the level of cysteate in the hippocampus, as a reflection of the higher sensitivity of the parietal lobe to oxygen deficiency, compared with the hippocampus.