bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interactions between civil society, business and government for environmental sustainability
Authors: Pozniakovska Nataliia , Savina Natalia , Mikluha Olesia , Pilyavets Viktor 
Published: December 2023

Abstract
The article examines the essence of civil society and reveals its main components in cooperation with business and government. The place and role of civil organisations and public are considered in the context of modern environmental requirements. An analysis of national features in the formation and development of civil society is provided. Trends in interactions of civil society, business and government in Ukraine have been revealed through the comparison with other countries. An attempt was made to understand the national civil movement as a prerequisite for the formation of civil society in Ukraine during the years of independence. Tools for assessing the sustainability and general viability of the civil society sector are classified according to various criteria. Global indicators of trust in various institutions of society and its institutional activity are analysed. There was carried out an analysis of the dynamics of the sustainability index for Ukraine. Guidelines for the institutional transformation of the interactions between domestic civil society, business, government have been worked out in order to substantiate the information and analytical provision.
Role of technological innovation for sustainable management of tourism organizations
Authors: Ilieva L , Todorova L 
Published: December 2023

Abstract
The principles of sustainable management are applicable to all sectors, and especially to tourism, as they relate to the environmental, economic and socio-cultural aspects of the development of the activity. Tourism and sustainable development are inextricably linked given that the tourism product is based on the natural resources and the preserved cultural identity of peoples. Tourism organizations shape their offering by establishing an appropriate balance between these three dimensions in order to offer an attractive tourism product. This is possible only by building a system for sustainable development of the tourist organization. In the present study, the relationship between innovation and sustainable management of tourism organizations is sought. For this purpose, the possibilities for innovation in the activity of the tourist organization are presented, the principles of sustainable management of the organization are clarified and the role of the system for sustainable management is outlined. As a result of the conducted research, technological innovations are presented that allow organizations to use resources more rationally and achieve sustainable development.
Delving into the anisotropic interlayer exchange in bilayer CrI3
Authors: Stavrić Srdjan , Barone Paolo , Picozzi Silvia 
Published: December 2023

Abstract
Bilayer CrI3 attracted much attention due to stacking-induced switching between the layered ferromagnetic and antiferromagnetic order. This discovery brought under the spotlight the interlayer Cr–Cr exchange interaction, which despite being much weaker than the intralayer exchange, plays an important role in shaping the magnetic properties of bilayer CrI3. In this work we delve into the anisotropic part of the interlayer exchange with the aim to separate the contributions from the Dzyaloshinskii–Moriya (DMI) and the Kitaev interactions (KI). We leverage the density functional theory calculations with spin Hamiltonian modeling and develop an energy mapping procedure to assess these anisotropic interactions with

μ

e
V

accuracy. After inspecting the rhombohedral and monoclinic stacking sequences of bilayer CrI3, we reveal a considerable DMI and a weak interlayer KI between the sublattices of a monoclinic bilayer. We explain the dependence of DMI and KI on the interlayer distance, stacking sequence, and the spin–orbit coupling strength, and we suggest the dominant superexchange processes at play. In addition, we demonstrate that the single-ion anisotropy in bilayer CrI3 is highly stacking-dependent, increasing by 50% from monoclinic to rhombohedral bilayer. Remarkably, our findings prove that iodines are highly efficient in mediating the DMI across the van der Waals gap, much owing to spatially extended 5p orbitals which feature strong spin–orbit coupling. Our study gives promise that the interlayer chiral control of spin textures, demonstrated in thin metallic films where the DMI is with a much longer range, can be achieved with similar efficiency in semiconducting two-dimensional van der Waals magnets.
Fabrication of Z-scheme ZnO/g-C3N4/ZnS nanocomposites using high power laser for methylene blue degradation
Authors: Alnoaimi Aljazi , Tamimi Naflah , Alade Ibrahim Olanrewaju , Manda Abdullah , Sultan Badriah , Akhtar Sultan , Fatty Muhammed , Elsayed Khaled A , Drmosh Qasem A 
Published: December 2023

Abstract
Photocatalysis plays a vital role in addressing environmental challenges by harnessing solar energy for efficient pollutant degradation. In this study, we investigate the photocatalytic activity of a ZnO/g-C3N4/ZnS composite system in the degradation of methylene blue, a widely used dye with detrimental effects on aquatic ecosystems. The composite materials were synthesized using a facile and scalable approach, and their structural properties, morphologies, sizes, and elemental compositions were characterized using different analytical techniques. The ZnO/g-C3N4/ZnS composite exhibited enhanced photocatalytic performance compared to individual components. Remarkably, the degradation efficiency reached 80% for the composite with a 30% ZnO composition, surpassing the efficiencies of ZnS alone (29%) and ZnS/g-C3N4 (65%). The composite’s higher degradation efficiency is due to synergistic semiconductor effects, enhancing charge transfer and reducing electron–hole recombination. ZnO incorporation increases active sites and surface area, improving interaction with methylene blue. The favorable band edge positions of ZnO aligned with ZnS and g-C3N4, facilitating the utilization of a broader spectrum of solar light. The composite’s photocatalytic activity was achieved under UV light irradiation, demonstrating its potential for sustainable and energy-efficient applications. This study highlights the significance of composite design and the Z-scheme concept in photocatalysis, offering insights into the development of advanced materials for environmental remediation. The findings contribute to the understanding of efficient solar-driven pollutant degradation and pave the way for the design and optimization of innovative photocatalytic systems for sustainable environmental solutions.
Biomass estimation models for Acacia saligna trees in restored landscapes
Authors: Hagazi Niguse , Kebede Mulat , Mokria Mulugeta , Birhane Emiru , Gebrekirstos Aster , Bräuning Achim 
Published: December 2023

Abstract

Acacia saligna, originating from Australia, is a naturalized multipurpose tree species widely grown to restore degraded lands of Africa. The contribution of A. saligna in biomass restoration can be quantified using a precise estimation of tree biomass carbon. This study developed species-specific allometric models and evaluated the spatial variation of tree biomass across restored areas in exclosures and open grazing landscapes. These models could play a considerable role in the monitoring of carbon dynamics across A. saligna planation dominated areas. We harvested, excavated, and weighed twenty-one sample trees representing different size classes to develop allometric models for the estimation of aboveground (AGB), belowground (BGB) and total tree (TB) biomass. The average dry-to-fresh mass ratio and the root-to-shoot ratio was 0.47 (±0.13) and 0.28 (±0.14), respectively. Tree biomass significantly correlated with diameter at breast height (r = 0.93; P < 0.001), diameter at stump height (r = 0.88, P < 0.001) and tree height (r = 0.56, P < 0.05). Our best biomass estimation models explained 86%, 82% and 87% of variations in AGB, BGB, and TB, respectively. Models using DSH and DSH & H explained 70%–78% of the variation in AGB, BGB, and TB. Estimated C-stock showed a significant relationship with stem density (R

2

= 0.91, P < 0.01). Estimated TB varied between 1.5–18 Mg ha−1 on grazed land and exclosures. Estimated C-stocks in the exclosure exceeded the estimated C-stock in the open grazing land by ∼60%. This implies that with proper management practices and enrichment planting A. saligna significantly contributes to increasing carbon accumulation on degraded landscapes, playing a key role in climate change mitigation efforts while improving land productivity.
The use of electronic health record embedded MRC-ICU as a metric for critical care pharmacist workload
Authors: Webb Andrew J , Carver Bayleigh , Rowe Sandra , Sikora Andrea 
Published: December 2023

Abstract

Objectives
A lack of pharmacist-specific risk-stratification scores in the electronic health record (EHR) may limit resource optimization. The medication regimen complexity-intensive care unit (MRC-ICU) score was implemented into our center’s EHR for use by clinical pharmacists. The purpose of this evaluation was to evaluate MRC-ICU as a predictor of pharmacist workload and to assess its potential as an additional dimension to traditional workload measures.

Materials and methods
Data were abstracted from the EHR on adult ICU patients, including MRC-ICU scores and 2 traditional measures of pharmacist workload: numbers of medication orders verified and interventions logged. This was a single-center study of an EHR-integrated MRC-ICU tool. The primary outcome was the association of MRC-ICU with institutional metrics of pharmacist workload. Associations were assessed using the initial 24-h maximum MRC-ICU score’s Pearson’s correlation with overall admission workload and the day-to-day association using generalized linear mixed-effects modeling.

Results
A total of 1205 patients over 5083 patient-days were evaluated. Baseline MRC-ICU was correlated with both cumulative order volume (Spearman’s rho 0.41, P &lt; .001) and cumulative interventions placed (Spearman’s rho 0.27, P &lt; .001). A 1-point increase in maximum daily MRC-ICU was associated with a 31% increase in order volume (95% CI, 24%-38%) and 4% increase in interventions (95% CI, 2%-5%).

Discussion and conclusion
The MRC-ICU is a validated score that has been previously correlated with important patient-centered outcomes. Here, MRC-ICU was modestly associated with 2 traditional objective measures of pharmacist workload, including orders verified and interventions placed, which is an important step for its use as a tool for resource utilization needs.
Bacterial natural product discovery by heterologous expression
Authors: Kadjo Adjo E , Eustáquio Alessandra S 
Published: December 2023

Abstract

Natural products have found important applications in the pharmaceutical and agricultural sectors. In bacteria, the genes that encode the biosynthesis of natural products are often colocalized in the genome, forming biosynthetic gene clusters. It has been predicted that only 3% of natural products encoded in bacterial genomes have been discovered thus far, in part because gene clusters may be poorly expressed under laboratory conditions. Heterologous expression can help convert bioinformatics predictions into products. However, challenges remain, such as gene cluster prioritization, cloning of the complete gene cluster, high level expression, product identification, and isolation of products in practical yields. Here we reviewed the literature from the past 5 years (January 2018 to June 2023) to identify studies that discovered natural products by heterologous expression. From the 50 studies identified, we present analyses of the rationale for gene cluster prioritization, cloning methods, biosynthetic class, source taxa, and host choice. Combined, the 50 studies led to the discovery of 63 new families of natural products, supporting heterologous expression as a promising way to access novel chemistry. However, the success rate of natural product detection varied from 11% to 32% based on four large-scale studies that were part of the reviewed literature. The low success rate makes it apparent that much remains to be improved. The potential reasons for failure and points to be considered to improve the chances of success are discussed.

One-Sentence Summary
At least 63 new families of bacterial natural products were discovered using heterologous expression in the last 5 years, supporting heterologous expression as a promising way to access novel chemistry; however, the success rate is low (11–32%) making it apparent that much remains to be improved—we discuss the potential reasons for failure and points to be considered to improve the chances of success. BioRender was used to generate the graphical abstract figure.
Complete Genome Sequence of Pseudomonas promysalinigenes Strain RL-WG26, a PGPR Isolated from the Rice Rhizosphere for Studying the Promotion of Plant Growth Under Salt Stress
Authors: Song Jia , Wang Yanyan , Weng Liyun , Ling Yu , Zhang Yueqing , Xue Yingbin , Hu Hanqiao , Ren Lei 
Published: December 2023

The Pseudomonas promysalinigenes strain RL-WG26, which was previously isolated from the rhizosphere of Sea Rice 86 (SR86), could promote the plant growth and alleviate the plant salt stress of SR86 by regulating the ion concentration in plants, increasing the dry weight and chlorophyll content of plants, and reducing the proline and malondialdehyde content in roots. Here, we report the complete genome sequence of Pseudomonas promysalinigenes strain RL-WG26 to lay a foundation for deciphering the molecular mechanisms of strain RL-WG26-mediated plant salt tolerance and to further the application potential of this strain. [Formula: see text] Copyright © 2023 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
Surgical Failure and Revision Strategy for Atlantoaxial Dislocation
Authors: Ma Xiangyang , Zou Xiaobao , Chen Zexing , Yang Haozhi , Chen Junlin , Ma Rencai , Fu Suochao , Xia Hong 
Published: December 2023

Study Design.
Retrospective study.

Objective.
To classify surgical failures following atlantoaxial dislocation, present strategies for revisions and evaluate the clinical results of revision surgery.

Summary of Background Data.
With the increase in atlantoaxial dislocation surgery, the number of surgical failures has gradually risen. However, current reports on atlantoaxial surgical revision are limited in scope. There remains a lack of summary regarding the causes of surgical failure, a detailed classification system, and no proposed strategy for revision surgery.

Methods.
109 cases of failed surgery following atlantoaxial dislocation were classified according to the reduction immediately after surgery and the fusion status before revision. The reduction, decompression, fusion status and outcomes following revision surgery were evaluated by X-ray, CT, MRI and JOA score. The data were analyzed statistically with a paired-samples t test and multivaraible logistic regression analysis.

Results.
The 109 patients were classified into three categories of failure: non-reduction with non-fusion (NR-NF, 73 cases), non-reduction with fusion (NR-F, 19 cases), and reduction with non-fusion (R-NF, 17 cases). Sixty-four patients underwent anterior revision, 21 posterior revision, and 24 anteroposterior revision. Postoperative complications were the primary cause of early revisions. After revision, complete decompression was achieved in all cases, anatomical reduction in 89 cases, significant improvement of JOA score in 77 cases, and fusion achieved in 86 cases. Twelve cases experienced surgical complications and 3 underwent a second revision.

Conclusions.
We found that NR-NF was the most common type of failure following surgery for atlantoaxial dislocation. Revision strategies can be guided according to our descriptive classification of failure, and revision surgery should focus on achieving adequate reduction, appropriate fixation and reliable fusion to optimize post-surgical outcomes.
BEST1 VARIANT ASSOCIATED WITH AN ATYPICAL MACULAR AND PERIPHERAL RETINAL PHENOTYPE
Authors: Singuri Srinidhi , DeBenedictis Meghan J. , Traboulsi Elias I. , Yuan Alex , Schur Rebecca M. 
Published: December 2023

Purpose:
Best vitelliform macular dystrophy is an inherited macular dystrophy associated with over 250 pathogenic variants of the Bestrophin-1 (BEST1) gene. Although several types of lesions of best vitelliform macular dystrophy are well-described, reports of phenotypic variations associated with rare genetic variants are limited.

Methods:
This was a retrospective case series performed in 2021 at a tertiary eye care center.

Patients:
Three members of one family referred to a tertiary eye care clinic for evaluation of their autosomal dominant macular dystrophy.

Results:
Study subjects presented with atypical findings of peripheral schisis-like lesions and atrophy with abnormal electroretinogram in addition to typical macular lesions found in best vitelliform macular dystrophy. Genetic analyses identified a heterozygous BEST1 c.227T>A, p.(Ile76Asn) pathogenic variant in all three subjects.

Conclusion:
This study represents the first report of the phenotype associated with the c.227T>A, p.(Ile76Asn) BEST1 variant, which—while mentioned twice in the literature—has not been previously described. The phenotype is unique, comprising features of typical best vitelliform macular dystrophy with electroretinogram and peripheral findings, suggestive of a panretinal dysfunction.
Decreasing ICU and Hospital Length of Stay through a Standardized Respiratory Therapist-driven Electronic Clinical Care Pathway for Status Asthmaticus
Authors: Lopez Merrick , Wilson Michele , Cobbina Ekua , Kaufman Danny , Fluitt Julie , Grainger Michele , Ruiz Robert , Abudukadier Gulixian , Tiras Michael , Carlson Bronwyn , Spaid Jeane , Falsone Kim , Cocjin Invest , Moretti Anthony , Vercio Chad , Tinsley Cynthia , Chandnani Harsha K. , Samayoa Carlos , Cianci Carissa , Pappas James , Chang Nancy Y. 
Published: December 2023

Introduction:
Status asthmaticus (SA) is a cause of many pediatric hospitalizations. This study sought to evaluate how a standardized asthma care pathway (ACP) in the electronic medical record impacted the length of stay (LOS).

Methods:
An interdisciplinary team internally validated a standardized respiratory score for patients admitted with SA to a 25-bed pediatric intensive care unit (PICU) at a tertiary children’s hospital. The respiratory score determined weaning schedules for albuterol and steroid therapies. In addition, pharmacy and information technology staff developed an electronic ACP within our electronic medical record system using best practice alerts. These best practice alerts informed staff to initiate the pathway, wean/escalate treatment, transition to oral steroids, transfer level of care, and complete discharge education. The PICU, stepdown ICU (SD ICU), and acute care units implemented the clinical pathway. Pre- and postintervention metrics were assessed using process control charts and compared using Welch’s t tests with a significance level of 0.05.

Results:
Nine hundred two consecutive patients were analyzed (598 preintervention, 304 postintervention). Order set utilization significantly increased from 68% to 97% (P < 0.001), PICU LOS decreased from 38.4 to 31.1 hours (P = 0.013), and stepdown ICU LOS decreased from 25.7 to 20.9 hours (P = 0.01). Hospital LOS decreased from 59.5 to 50.7 hours (P = 0.003), with cost savings of $1,215,088 for the patient cohort.

Conclusions:
Implementing a standardized respiratory therapist-driven ACP for children with SA led to significantly increased order set utilization and decreased ICU and hospital LOS. Leveraging information technology and standardized pathways may improve care quality, outcomes, and costs for other common diagnoses.
Genetic heterogeneity in theSalmonellaTyphi Vi capsule locus: A population genomic study from Fiji
Authors: Getahun Strobel Aneley , Hayes Andrew J. , Wirth Wytamma , Mua Mikaele , Saumalua Tiko , Cabenatabua Orisi , Soqo Vika , Rosa Varanisese , Wang Nancy , Lacey Jake A. , Hocking Dianna , Valcanis Mary , Jenney Adam , Howden Benjamin P. , Duchene Sebastian , Mulholland Kim , Strugnell Richard A. , Davies Mark R. 
Published: December 2023

AbstractTyphoid fever is endemic in many parts of the world and remains a major public health concern in tropical and sub-tropical developing nations, including Fiji. To address high rates of typhoid fever, the Northern Division of Fiji is implementing a mass vaccination with typhoid conjugate vaccine (Vi-polysaccharide conjugated to tetanus toxoid) as a public health control measure in 2023. In this study we define the genomic epidemiology ofS. Typhi in the Northern Division prior to island-wide vaccination, sequencing 85% (n=419) of the total cases from the Northern Division and Central Divisions of Fiji that occurred in the period 2017-2019. We found elevated rates of nucleotide polymorphisms intviD and tviEgenes (responsible for Vi-polysaccharide synthesis) relative to core genome levels within the Fiji endemicS. Typhi genotype 4.2. Expansion of these findings within a globally representative database of 12,382S. Typhi (86 genotyphi clusters) showed evidence of convergent evolution of the sametviEmutations across theS. Typhi population, indicating thattviselection has occurred both independently and globally. The functional impact oftvimutations on the Vi-capsular structure and other phenotypic characteristics are presently unknown, yet commonly occurringtviEpolymorphisms localise adjacent to predicted active site residues when overlayed against the predicted TviE protein structure. Given the central role of the Vi-polysaccharide inS. Typhi biology and vaccination, further integrated epidemiological, genomic, and phenotypic surveillance is required to determine the spread and functional implications of these mutations.