bluuebunny/crossref_metadata_2025_split huggingface dataset:
Photosynthetic animals and where to find them: abundance and size of a solar-powered sea slug in different light conditions
Authors: Vital Xochitl G. , Simões Nuno , Cruz Sónia , Mascaró Maite 
Published: October 2023

AbstractThree populations of the solar-powered sea slugElysia crispataon reefs from the southern Gulf of Mexico and the Caribbean were analyzed. The aim was to describe and compare the changes in abundance and size of this species in different localities, as a function of depth and time-of-day. We hypothesized that differences in abundance would be related to locality, time of the day and depth, and differences in size would be related to locality and time of the day. Using snorkeling and SCUBA diving, all individuals within quadrats were counted and measured. A total of 680 organisms were recorded at Verde, Arcas and Puerto Morelos (PM) reefs at five times of the day (sunrise, morning, zenith, evening, and night) and depths of 0–13 m. Zero inflated negative binomial (ZINB) regressions adjusted to abundance data showed thatE. crispatain Arcas and Verde reefs is expected to be more abundant (> 50) in shallow depths (< 2 m) at any time of the day except sunrise, whereas a low abundance (≤ 1 organism) is predicted in PM regardless of depth and time-of-day. According to linear models, size was not related to depth, but was related to locality and time-of-day, with sea slugs from Arcas and Verde having similar size, and both larger than those in PM. This information suggests that this sea slug is capable of moving within the reefs and helps to understand the unique biological phenomena of kleptoplasty.
Integrating TSPO PET imaging and transcriptomics to unveil the role of neuroinflammation and amyloid-β deposition in Alzheimer’s disease
Authors: Zhang Miao , Qian Xiao-hang , Hu Jialin , Zhang Yaoyu , Lin Xiaozhu , Hai Wangxi , Shi Kuangyu , Jiang Xufeng , Li Yao , Tang Hui-dong , Li Biao 
Published: October 2023

Abstract
Purpose
Despite the revealed role of immunological dysfunctions in the development and progression of Alzheimer’s disease (AD) through animal and postmortem investigations, direct evidence regarding the impact of genetic factors on microglia response and amyloid-β (Aβ) deposition in AD individuals is lacking. This study aims to elucidate this mechanism by integrating transcriptomics and TSPO, Aβ PET imaging in clinical AD cohort.

Methods
We analyzed 85 patients with PET/MR imaging for microglial activation (TSPO, [18F]DPA-714) and Aβ ([18F]AV-45) within the prospective Alzheimer’s Disease Immunization and Microbiota Initiative Study Cohort (ADIMIC). Immune-related differentially expressed genes (IREDGs), identified based on AlzData, were screened and verified using blood samples from ADIMIC. Correlation and mediation analyses were applied to investigate the relationships between immune-related genes expression, TSPO and Aβ PET imaging.

Results
TSPO uptake increased significantly both in aMCI (P < 0.05) and AD participants (P < 0.01) and showed a positive correlation with Aβ deposition (r = 0.42, P < 0.001). Decreased expression of TGFBR3, FABP3, CXCR4 and CD200 was observed in AD group. CD200 expression was significantly negatively associated with TSPO PET uptake (r =—0.33, P = 0.013). Mediation analysis indicated that CD200 acted as a significant mediator between TSPO uptake and Aβ deposition (total effect B = 1.92, P = 0.004) and MMSE score (total effect B =—54.01, P = 0.003).

Conclusion
By integrating transcriptomics and TSPO PET imaging in the same clinical AD cohort, this study revealed CD200 played an important role in regulating neuroinflammation, Aβ deposition and cognitive dysfunction.
Environmental impact and nutritional quality of adult diet in France based on fruit and vegetable intakes
Authors: Komati Nathalie , Vieux Florent , Maillot Matthieu , Darmon Nicole , Calvarin Johanna , Lecerf Jean-Michel , Amiot Marie-Josèphe , Belzunces Luc , Tailliez Delphine 
Published: October 2023

Abstract
Purpose
To describe the nutritional quality and environmental impact of self-selected diets of adults in France in relation to their fruit and vegetable (FV) intakes.

Methods
Estimates of food and nutrient intakes were taken from the national INCA3 Survey on food intakes carried out in France in 2014–2015. The population (n = 2121 adults) was split into five quintiles of FV intakes, in g/d (Q1 representing the lowest intake, and Q5 the highest). The nutritional quality of diets was assessed through 4 indicators: mean adequacy ratio (MAR), solid energy density, mean excess ratio (MER) and Programme National Nutrition Santé guideline score 2 (PNNS-GS2). The environmental impacts were measured with environmental footprint (EF) scores and 4 additional indicators: climate change, ozone depletion, fine particulate matter and water use. Indicators were compared between quintiles. Analysis was conducted on diets adjusted to 2000 kcal.

Results
MAR and PNNS-GS2 increased with increased FV quintiles, while solid energy density decreased. Fibre, potassium, vitamin B9 and vitamin C densities increased with increasing FV intakes. Climate change, ozone depletion and fine particulate matter impacts of diets decreased with increasing quintiles of FV consumption. Conversely, water use impact increased.

Conclusion
Higher intake of FV is associated with higher nutritional quality of diets and lower environmental impact, except for water use. Given the benefits of fruit and vegetables for human health and the environment, their negative impact on water use could be improved by working on the agricultural upstream, rather than by changing individuals’ food choices and reducing their consumption.
Radioactive nanosized colloids and indocyanine green identify the same sentinel lymph nodes in oral squamous cell carcinoma
Authors: Hingsammer Lukas , Schönegg Daphne , Gander Thomas , Lanzer Martin 
Published: October 2023

Abstract
Purpose
Near-infrared fluorescence imaging using indocyanine green (ICG) combined with radioactive markers has the potential to improve sentinel lymph-node (SLN) mapping in oral squamous cell carcinoma (OSCC). This study aimed to evaluate the ability of 99mTc and ICG in identifying the sentinel lymph nodes in patients with early stage OSCC.

Methods
Data were collected prospectively, and a retrospective analysis of 15 patients with early stage OSCC and a cN0 neck was performed. All patients received peritumoral injection of 99mTc the day before surgery and ICG was administered intraoperatively. Intentionally, the application of the two different tracers were done by two different physicians with varying degrees of experience. The number of identified lymph nodes positive for 99mTc and ICG, the overlap or possible discrepancies of both methods, and the time until fluorescence signals of ICG were detected were noted.

Results
In all patients, a 100% agreement in sentinel lymph-node identification was achieved, regardless of both the exact location of the peritumoral injection and the experience of the injecting surgeon. Time until ICG accumulation in the sentinel lymph node was consistently found to be between 1 and 3 min.

Conclusion
ICG constitutes a viable and useful addition to 99mTc for intraoperative sentinel lymph-node detection in this study.
Swinv2-Imagen: hierarchical vision transformer diffusion models for text-to-image generation
Authors: Li Ruijun , Li Weihua , Yang Yi , Wei Hanyu , Jiang Jianhua , Bai Quan 
Published: October 2023

AbstractRecently, diffusion models have been proven to perform remarkably well in text-to-image synthesis tasks in a number of studies, immediately presenting new study opportunities for image generation. Google’s Imagen follows this research trend and outperforms DALLE2 as the best model for text-to-image generation. However, Imagen merely uses a T5 language model for text processing, which cannot ensure learning the semantic information of the text. Furthermore, the Efficient UNet leveraged by Imagen is not the best choice in image processing. To address these issues, we propose the Swinv2-Imagen, a novel text-to-image diffusion model based on a Hierarchical Visual Transformer and a Scene Graph incorporating a semantic layout. In the proposed model, the feature vectors of entities and relationships are extracted and involved in the diffusion model, effectively improving the quality of generated images. On top of that, we also introduce a Swin-Transformer-based UNet architecture, called Swinv2-Unet, which can address the problems stemming from the CNN convolution operations. Extensive experiments are conducted to evaluate the performance of the proposed model by using three real-world datasets, i.e. MSCOCO, CUB and MM-CelebA-HQ. The experimental results show that the proposed Swinv2-Imagen model outperforms several popular state-of-the-art methods.
Translating the Cluster Headache Quality of Life Questionnaire (CHQ) from English to Dutch with the TRAPD method
Authors: Naber Willemijn C. , Brandt Roemer B. , Figetakis Dimitris D. , Jahanshahi Marjan , Terwindt Gisela M. , Fronczek Rolf 
Published: October 2023

Abstract
Objective
Cluster headache is associated with a decreased quality of life (QoL). The increased focus on patient-reported outcome measures (PROMS) has led to the creation of a tailored Cluster Headache Quality of Life scale (CHQ). Our objective was to create and authenticate a Dutch version of the CHQ (CHQ-D).

Methods
The TRAPD model (Translation, Review, Adjudication, Pretesting, Documentation) was used to translate the CHQ from English to Dutch and ensure cross-cultural adaption. Pre-testing was performed in n = 31 participants, and validity was in a new sample of n = 40 participants who completed the CHQ twice at a 2-day interval. Intraclass correlation coefficient (ICC) and Cronbach’s alpha were used to assess the validity and reproducibility of the CHQ-D.

Results
To produce the CHQ-D, we made five modifications based on pretesting. Participants finished the questionnaire in a median time of 10 min (IQR:10.0, 17.5) and 90% within 20 min. The majority of participants (74.2%) did not find it burdensome at all. The reliability of the CHQ-D was excellent (Cronbach’s alpha: 0.94; ICC: 0.94).

Conclusion
The CHQ-D is a valid and practical instrument for QoL in individuals with cluster headache. We aim to use CHQ-D as PROM in clinical research in the Netherlands to enforce international collaborations and comparisons of studies.
Digitalization and changes to work organization and management in the Norwegian petroleum industry
Authors: Melberg Kjersti , Gressgård Leif Jarle 
Published: October 2023

AbstractThis article analyses how implementation and use of digital technologies involve changes in work content, organization, and management in the petroleum industry. This is important, given that the industry is in a phase with mature technology and heavy pressure on efficiency and cost-effectiveness, at the same time as older systems and work processes prevail. The article draws on data acquired through interviews in a number of companies, organizations and specialist teams. The results show that far-reaching digitalization will mean radical changes to the way employees and managers work. The level of success in using digital technologies can be related to the ability to alter the content and form of work and expertise requirements, while retaining trust in technology and coping with uncertainty. A key conclusion is that clarifications related to work processes, roles, and responsibilities between the various actors in the supply chain are the most significant obstacles to successful technology adoption.
Diffusion of climate policy integration in adaptation strategies: translating the EU mandate into UK and Danish national contexts
Authors: Jensen Anne , Nielsen Helle Ørsted , Russel Duncan 
Published: October 2023

AbstractIn this paper, we examine how the EU Climate Adaptation Strategy and especially its pivotal principle of policy integration of climate adaptation has diffused into the climate adaptation strategies of Member States. We explore how this quest for climate adaptation policy integration (CPI) was pushed by vertical diffusion of the framing and policy mixes launched at the EU level. To do so, we analyse and compare national climate adaptation strategies in two EU Member States—the UK and Denmark—during 2013–2021, which witnessed Brexit and increased attention to climate impacts. Conceptually and analytically, we draw on the policy diffusion literature centring on four potential drivers of vertical policy diffusion: interests, rights, ideology and recognition. Furthermore, to scrutinize what is diffused, we conceptualize climate policy integration including the rationale and policy instruments for climate policy integration. We find that both countries’ approaches to climate change adaptation have been shaped by rights-based diffusion in a mixture of shadow hierarchy, soft power and activation of other policy areas with binding directives and observe how what appears to be asymmetrical diffusion has strong elements of symmetrical diffusion. We further identify divergence between the cases before and after Brexit and in mandating local level actions.
How do countries frame climate change? A global comparison of adaptation and mitigation in UNFCCC National Communications
Authors: Wright Sarah Judith , Sietsma Anne , Korswagen Stefanie , Athanasiadis Ioannis N. , Biesbroek Robbert 
Published: October 2023

AbstractSelf-reporting is an important mechanism of the UNFCCC to collect information about what countries are doing to achieve their climate change mitigation and adaptation targets and how much progress has been made. Here we empirically test four hypotheses about what countries prioritise in their self-reporting through the National Communications. Using quantitative text analysis methods (structural topic modelling and keyness statistics), we analyse over 600 submissions (from 1994 to 2019) and find evidence that vulnerable countries highlight impacts, vulnerability, and adaptation rather than mitigation targets, whereas high-emitting countries tend to focus their messaging more on mitigation. Despite the Paris Agreement being considered a “watershed moment”, we find no statistically significant increase in focus on climate solutions post-Paris, and no significant increase in attention to adaptation. Our global assessment and the methods used offer a novel perspective to understand what gets framed as important by governments. Finally, we provide reflections on how self-reporting mechanisms can be used for global stocktaking of progress on climate action.
How do the activity patterns of people with chronic pain influence the empathic response of future health professionals: an experimental study*
Authors: Esteve Rosa , Serrano-Ibáñez Elena R. , Castillo-Real Sheila , Ramírez-Maestre Carmen , López-Martínez Alicia E. 
Published: October 2023

AbstractEmpathy in healthcare professionals is associated with better treatment outcomes and higher satisfaction among patients with chronic pain. Activity patterns play an essential role in the adjustment of these patients and, as a pain behaviour, may have a communicative function and elicit distinct empathic responses. This study investigated whether the activity pattern profiles characteristic of these patients had differential effects on the empathic response (empathic distress and compassion/sympathy) of future healthcare professionals. Healthcare professionals should improve their knowledge about the role of different activity patterns in the well-being of people with chronic pain and receive specific training in empathic skills. We controlled for several variables that could affect the empathic response (sex, age, academic degree, previous experience of chronic pain, and dispositional empathy).A total of 228 undergraduates performed an experimental task using vignettes depicting four activity pattern profiles displayed by people with chronic pain and completed questionnaires measuring dispositional and situational empathy. We conducted a MANCOVA analysis.Undergraduates showed more compassion/sympathy toward the medium cycler profile than toward the doer profile. Participants’ age was associated with empathic distress. Sex, academic degree, and previous experiences with chronic pain were not associated with their empathic response to the vignettes. Dispositional perspective-taking and empathic concern were significantly associated with compassion/sympathy responses, and personal distress was significantly associated with empathic distress.Activity pattern profiles may have a communicative function and elicit different empathic responses toward people with chronic pain. Individual differences in dispositional empathy play an important role on situational empathic responses.
Cultural Adaption, Translation, Preliminary Reliability and Validity of Key Psychological and Behavioural Measures for 18 to 25 Year-Olds Living with HIV in Uganda: A Multi-Stage Approach
Authors: Evangeli Michael , Foster Caroline , Musiime Victor , Fidler Sarah , Seeley Janet , Frize Graham , Uwizera Annette , Price Joseph 
Published: October 2023

AbstractHIV remains a significant public health issue among young adults living in Uganda. There is a need for reliable and valid measures of key psychological and behavioural constructs that are related to important outcomes for this population. We translated, adapted and tested the psychometric properties of questionnaires measuring HIV stigma, HIV disclosure cognitions and affect, antiretroviral therapy (ART) adherence, social support, personal values, and hope, using a multi-step process. This included: translation, back-translation, expert review, cognitive interviewing, readability and assessments of internal consistency with 93 young adults (18–25 years) living with perinatally acquired HIV in Uganda. Preliminary criterion validity was assessed by examining relationships between the adapted measures and wellbeing, HIV disclosure behaviour, HIV disclosure intention and viral load suppression. The measures all showed acceptable reliability and every questionnaire apart from the Agentic and Communal Value Scale was easy to read. Those scales measuring HIV disclosure affect and cognitions, social support, HIV stigma and hope showed relationships with other constructs suggestive of validity. There is preliminary evidence to support the use of these measures in research and clinical contexts for young adults living with perinatally acquired HIV in Uganda.
Guiding the integration of analytics in business operations through a maturity framework
Authors: Menukin Olga , Mandungu Catherine , Shahgholian Azar , Mehandjiev Nikolay 
Published: October 2023

AbstractThe analytics function is growing in importance as the digitisation of business operations and markets leads to the generation of ever-increasing amounts of data. Analysing this data in a manner aligned with company priorities and structures can generate value through supporting effective decision-making, rapid product innovation, supply chain visibility and other aspects of intra- and inter-company operations. To guide the growth we derive a novel maturity framework focused on driving the Analytics-Business alignment, covering a number of diverse organisational facets such as data, leadership support, processes, data management, governance, technology and people. It differentiates itself by using a firm theoretical foundation and providing guidance for analytics capability development instead of simply diagnosing the existing maturity level. To guide development, it distinguishes between two aspects of maturity – a “state” aspect, which is used to assess the present situation in an organisation, and a “management” aspect, which evaluates management attitude in order to establish the next stage of analytics growth. The framework has been implemented in a web-based tool and its utility has been demonstrated by obtaining feedback from 64 managers from a variety of sectors, who have praised its ability to integrate diagnosis of the current situation with guidance on the next steps necessary to develop analytics maturity.
Phosphorus enrichment enabled Amorpha fruticosa to invade on the floodplain of the Tagliamento River, Italy
Authors: Edwards Peter , Hügli Christian , Olde Venterink Harry , Ramseier Dieter 
Published: October 2023

AbstractThe North American nitrogen-fixing shrub Amorpha fruticosa (false indigo) is an aggressive invader of riverine habitats in Europe, though the reasons for its success are poorly understood. We hypothesized that its spread on the floodplain of the Tagliamento River in Northern Italy was enabled by anthropogenic phosphorus (P) enrichment. To investigate this hypothesis, we surveyed seed production at different locations along the river and performed a growth chamber experiment in which seedlings of three common floodplain shrubs (A. fruticosa, Salix eleagnos and Buddleja davidii) were grown at 10 levels of both nitrogen (N) and P. As a bioassay of N and P availabilities, we analyzed concentrations of these nutrients in Salix eleagnos leaves collected at different positions along the river. P availability was significantly higher in the lower reaches of the river, where A. fruticosa was abundant, than at its upstream limit. Numbers of A. fruticosa seeds per inflorescence increased strongly in a downstream direction and there was a trend for higher seed weight. In the growth experiment, A. fruticosa was more P-demanding than the other species, producing little biomass and no rhizobial nodules at low P. It also exhibited greater plasticity than the other species in both root mass fraction and ratio of longest root length to root mass. We conclude that anthropogenic P enrichment enabled A. fruticosa to invade what was originally a very oligotrophic environment. This N2-fixing shrub exhibits greater phenotypic plasticity than native S. eleagnos, giving it a competitive advantage under conditions of high P availability.
Assessment of dimethyl sulphide odorous emissions during coal extraction process in Coal Mine Velenje
Authors: Uranjek Gregor , Horvat Milena , Milačič Radmila , Rošer Janez , Kotnik Jože 
Published: October 2023

AbstractUnderground coal extraction at Coal Mine Velenje occasionally gives rise to odour complaints from local residents. This manuscript describes a robust quantification of odorous emissions of mine sources and a model-based analysis aimed to establish a better understanding of the sources, concentrations, dispersion, and possible control of odorous compounds during coal extraction process. Major odour sources during underground mining are released volatile sulphur compounds from coal seam that have characteristic malodours at extremely low concentrations at micrograms per cubic metre (μg/m3) levels. Analysis of 1028 gas samples taken over a 6-year period (2008–2013) reveals that dimethyl sulphide ((CH3)2S) is the major odour active compound present in the mine, being detected on 679 occasions throughout the mine, while hydrogen sulphide (H2S) and sulphur dioxide (SO2) were detected 5 and 26 times. Analysis of gas samples has shown that main DMS sources in the mine are coal extraction locations at longwall faces and development headings and that DMS is releasing during transport from main coal transport system. The dispersion simulations of odour sources in the mine have shown that the concentrations of DMS at median levels can represent relatively modest odour nuisance. While at peak levels, the concentration of DMS remained sufficiently high to create an odour problem both in the mine and on the surface. Overall, dispersion simulations have shown that ventilation regulation on its own is not sufficient as an odour abatement measure.