bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploratory analysis of the knowledge, attitudes and perceptions of healthcare workers about arboviruses in the context of surveillance in the Republic of Guinea
Authors: Bangoura Salifou Talassone , Hounmenou Castro Gbêmêmali , Sidibé Sidikiba , Camara Saidouba Cherif , Mbaye Aminata , Olive Marie-Marie , Camara Alioune , Delamou Alexandre , Keita Alpha-Kabinet , Delaporte Eric , Khanafer Nagham , Touré Abdoulaye 
Published: December 2023

Background
The escalating risk and contemporary occurrences of arbovirus infections prompt a critical inquiry into the ability of nations to execute efficient surveillance systems capable to detect, prevent and respond to arbovirus outbreaks. Healthcare workers (HCWs) are the major actors in the surveillance of infectious diseases with epidemic potential. The objective of this study was to evaluate the knowledge, attitudes and perceptions of HCWs regarding arboviruses in the public health facilities of Conakry, Guinea.

Methods
A cross-sectional survey was conducted during the from December 27, 2022, to January 31, 2023, encompassing from public health facilities in Conakry. The data collection process encompassed various aspects, including the characteristics of health facilities, socio-demographic and professional attributes of HCWs, the information received concerning arboviruses and the sources of information, as well as a series of inquiries designed to evaluate their knowledge, attitudes and perceptions. Subsequently, scores were computed for knowledge, attitude and perception. To identify the factors influencing the knowledge, attitudes, and perceptions of HCWs regarding arboviruses, Decision Tree and Inference Conditional Tree models were used.

Results
A total of 352 HCWs participated in the study, comprising 219 from national hospitals, 72 from municipal hospitals and 61 from primary health centers. More than half of the respondents (54.3%) had never received information on arboviruses. Only 1% of the respondents had good knowledge about arboviruses, 95.7% had a negative attitude about arboviruses. Moreover, nearly 60% of the respondents had a moderate perception and 24.1% had a good perception. The analysis revealed significant associations between the knowledge and attitudes of respondents concerning arboviruses and their years of professional experience and age.

Conclusion
This study highlights the imperative requirement for comprehensive training targeting HCWs to enhance their capacity for early case detection within healthcare facilities. Additionally, there is a crucial need for analogous studies adopting a mixed-methods approach across all healthcare regions in Guinea.
Effect of pueraria on left ventricular remodelling in HFrEF: A systematic review and meta-analysis
Authors: Shi Lipeng , Huang Lumei , Yin Erqian , Deng Jingwei , Du Xuqin 
Published: December 2023

Background
Heart failure with reduced ejection fraction (HFrEF) is a prevalent cardiovascular disease globally, posing a significant burden on healthcare and society. Left ventricular remodelling is the primary pathology responsible for HFrEF development and progression, leading to increased morbidity and mortality. Pueraria, a traditional Chinese herbal medicine and food, is commonly used in China to treat HFrEF. Accumulating evidence suggests that pueraria can effectively reverse left ventricular remodelling in HFrEF patients. This meta-analysis aims to assess the impact of pueraria on left ventricular remodelling in HFrEF patients.

Methods
Eight electronic databases, including PubMed, EMBASE, Clinicaltrials.gov, Cochrane Library, Wanfang, CNKI, CQVIP, and CBM were searched for literature from inception to June 2023. All randomized controlled trials (RCTs) using pueraria in the treatment of HFrEF were included. The Cochrane Risk of Bias tool was utilized for RCTs’ methodological evaluation, while Review Manager 5.4.1 was used to analyze the data.

Results
Nineteen RCTs with a total of 1,911 patients (1,077 males and 834 females) were identified. Meta-analysis indicated that combination medication of pueraria and conventional medicine (CM) was superior to the CM alone in raising left ventricular ejection fraction (LVEF; MD = 6.46, 95% CI, 4.88 to 8.04, P < 0.00001), and decreasing left ventricular end-diastolic diameter (LVEDD; MD = -4.78, 95% CI, -6.55 to -3.01, P < 0.00001), left ventricular end-Systolic diameter (LVESD; MD = -3.98, 95% CI, -5.98 to -1.99, P < 0.00001) and N-terminal pro-brain natriuretic peptide (NT-proBNP; MD = -126.16, 95% CI, -185.30 to -67.03, P < 0.0001). Besides, combination medication improved clinical efficacy rate (RR = 3.42, 95% CI, 2.54 to 4.59, P < 0.00001), 6-min walk test (6-MWT; MD = 65.54, 95% CI, 41.77 to 89.31, P < 0.00001), and TCM syndrome score efficacy (RR = 3.03, 95% CI, 1.57 to 5.83, P = 0.0009). Regarding safety, no difference was observed for adverse events (RR = 0.59, 95% CI, 0.22 to 1.54, P = 0.28).

Conclusion
The use of pueraria combined with conventional medicine in HFrEF patients has superiority over conventional medicine alone in ameliorating cardiac function and reversing left ventricular remodeling. Moreover, combination medication has no increase in adverse drug events. Given some limitations, more prudence and high-quality clinical trials are needed in the future to verify the conclusions.
‘Caligrafía vegetal’, una nueva lectura del paisaje a través de la escultura
Authors: Linaza Iglesias Marta 
Published: December 2023

Caligrafía vegetal, proyecto que he realizado entre 2021 y 2023 se presenta como reflexión sobre las prácticas artísticas contemporáneas vinculadas a la naturaleza. Simultaneando el cuidado de las plantas y el trabajo artístico ocurre una simbiosis entre ambas actividades, muy interesante desde el punto de vista de la investigación plástica. El título del proyecto recoge el carácter de código desconocido, que da paso a una nueva narración, dando voz a una alternativa a lo real. De la importancia que tiene como recurso de vida, se señala su valor como alimento de la experiencia artística, resultando unas obras que exploran las nociones de positivo y negativo, la idea de la producción en arte como algo intrínseco a la vida y la necesidad de cuidar y entender el entorno como una de las claves para resaltar la importancia de nuestro ecosistema y un desarrollo humano pleno.
Magnetoelastic Losses in the Linear Response Region for Three- and Four-Axis Idealized Magnets
Authors: Petrova L.P. , Ignatenko N.M. , Gromkov A.S. 
Published: December 2023

In the presented studies, a description of the losses related to relaxation processes in idealized three- and four-axis ferromagnets, as well as ferrites, is considered for the case of a linear response (small perturbations) on the basis of a macroscopic approach. The description takes into account reversible 90° displacements of domain walls (DW) of concentrations (с), ways of DW pinning by linear defects, and processes of DW displacements and rotations of the spontaneous magnetization vector I⃗s, caused by a longitudinal elastic stress wave σ. As a result, the anisotropy of amplitude-independent losses emerges due to displacement processes. Frequency dependence of losses is obtained with consideration of the magnetic symmetry of the crystal, its magnetostructural parameters, and the concentration of magnetic phases ci. The paper also describes the internal frictionn Q-1, the absorption coefficient a, the velocity of propagation of elastic vibrations v and the Δ (1/E)-effect, thus allowing to reveal the texture in the distribution of DWs by their types.
It is shown that if the relaxation times of rotation processes τ = β / 2K1 and displacement processes τc = βс / mω20 are the same, then the maxima of the dependence of internal friction on frequency Qc-1(ω) and QB-1(ω) superimpose on each other.
The revealed features of magneto-elastic energy dissipation are of interest for laboratory studies and have promising applications in practice for determining the orientation of crystals, describing the texture, and calculating the differential ΔЕ-effect in magnets. The features of the ΔЕ-effect for the considered cases are also revealed.
Genetic polymorphism of populations and phylogeny of the Central Siberian Polygonum (Polygonaceae) section using ISSR and chloroplast markers
Authors: Yamskikh Irina E. , Tupitsyna Natalya N. , Ryabova Ksenya K. , Kutsev Maxim G. 
Published: December 2023

This article is devoted to the study of genetic polymorphism of populations and phylogeny of Polygonum section using ISSR and chloroplast markers. Section Polygonum is a taxonomically complex group. Identification of individuals is complicated because of the small size of plants, the processes of interspecific hybridization, heterocarpy, phenological and ecological plasticity. In this work, the genetic variability of six populations of five knotweed species growing in Krasnoyarsk was studied. ISSR analysis revealed that the level of genetic diversity in the populations varies from 4.17 % to 35.83 % and has maximum values for genetically close species P. sabulosum (P = 35.83 %) and P. arenastrum (P = 22.5–30 %). Minimum values of genetic diversity were observed for populations of P. aviculare (P = 4.17 %) and P. calcatum (P = 5 %). The studied populations are characterized by a very high level of genetic differentiation (Gst = 0.78) and reliably belong to different species. On the similarity dendrogram (UPGMA), individuals of these species form clearly distinct clades. The genetic structure of populations using STRUCTURE also shows a reliable division of individuals into 5 clusters corresponding to the studied species. Phylogenetic analysis using the trnL-trnF chloroplast region shows the presence of a 5-nucleotide deletion and two transversions that makes it possible to divide the studied group of Polygonum into two morphologically different clusters. The first group is formed by P. arenastrum, P. calcatum, P. caspicum, P. sabulosum and characterized by the absence of a main shoot, a gradual reduction of leaves to the top of shoots and the perianth dissection by 1/2 of its length. The second group includes P. aviculare, P. boreale, P. neglectum, P rectum that have a main shoot, heterophilly, perianth dissection by 2/3–3/4 of its length. Two substitutions have been identified in the matK sequences, however it is less informative for solving taxonomic issues of the studied group.
INOVASI SISTEM DIGITAL PADA TATA KELOLA KOTA SURABAYA DALAM MENCAPAI PERTUMBUHAN KOTA GOOD GOVERNANCE
Authors: Qatrunnada Darin , Utomo Ryoji , Putri Safira 
Published: December 2023

Surabaya merupakan Salah satu kota di Indonesia di daerah Jawa Timur yang mendapat predikat pemerintah responsif dan inovatif dalam hal penerapan good governance karena berhasil mengembangkan e-Government miliknya. Dasar dari hal tersebut bisa dilihat dari ketersediaan variasi produk pemerintahan terutama untuk pelayanan publik yang sudah berbasis internet. Variasi produk pemerintahan berbasis internet ini mulai diterapkan di Surabaya sudah hampir 5 tahun lalu, dan pada saat itu Walikota Surabaya adalah Ibu Tri Rismaharini. Ibu Tri Rismaharini selaku Walikota Surabaya periode 2010 hingga 2015 dan periode 2016 hingga 2020 menerapkan e-Government karena ingin berfokus pada pengembangan seluruh pelayanan sehingga bisa diakses secara online, misalkan pada sistem pengelolaan keuangan daerah, kesehatan, sumber daya manusia, perizinan, pendidikan, dan masih banyak fasilitas lainnya. Artikel memiliki tujuan untuk mengkaji dan mengidentifikasi secara jelas bagaimana penerapan pelayanan publik Kota Surabaya berbasis sistem digital dalam mencapai pertumbuhan kota yang good governance. Penelitian ini ingin melihat perkembangan e-Government di Surabaya khususnya pada periode Ibu Tri Rismaharini dan Walikota Surabaya saat ini yaitu Bapak Eri Cahyadi. Metode yang digunakan pada penelitian ini adalah metode kualitatif yang menggunakan analisis deskriptif dengan teknik studi literatur. Sedangkan untuk pengumpulan data pada penelitian ini menggunakan studi literature pada penelitian terdahulu yang relevan untuk dijadikan sebagai acuan atas penelitian yang akan dilakukan. Hasil penelitian ini menunjukkan bahwa inovasi sistem digital pada tata kelola Kota Surabaya dalam mencapai pertumbuhan kota good governance menggunakan beberapa aplikasi bagi warga Surabaya seperti e-KTP, Suroboyo Bus, e-Health, e-UMKM, e-Budgeting, e-Surat. Implementasi e-Government di Kota Surabaya banyak berpengaruh pada dua hal, pertama peningkatan kualitas pelayanan publik dan pengurangan praktik korupsi pada organisasi birokrasi atau sebagai komunikasi antar warga dengan pemerintah.
Solver-In-The-Loop Cluster Resource Management for Database-as-a-Service
Authors: König Arnd Christian , Shan Yi , Newatia Karan , Marshall Luke , Narasayya Vivek 
Published: December 2023

In Database-as-a-Service (DBaaS) clusters, resource management is a complex optimization problem that assigns tenants to nodes, subject to various constraints and objectives. Tenants share resources within a node, however, their resource demands can change over time and exhibit high variance. As tenants may accumulate large state, moving them to a different node becomes disruptive, making intelligent placement decisions crucial to avoid service disruption. Placement decisions need to account for dynamic changes in tenant resource demands, different causes of service disruption, and various placement constraints, giving rise to a complex search space.
In this paper, we show how to bring combinatorial solvers to bear on this problem, formulating the objective of minimizing service disruption as an optimization problem amenable to fast solutions. We implemented our approach in the Service Fabric cluster manager codebase. Experiments show significant reductions in constraint violations and tenant moves, compared to the previous state-of-the-art, including the unmodified Service Fabric cluster manager, as well as recent research on DBaaS tenant placement.
Clinical specificity of two assays for immunoglobulin kappa and lambda free light chains
Authors: Farnsworth Christopher W. , Roemmich Brittany , Spears Grant M. , Murray David L. , Dispenzieri Angela , Willrich Maria Alice V. 
Published: December 2023

Abstract

Objectives
Free light chain (FLC) assays and the ratio of κ/λ are recommended for diagnosis, prognosis and monitoring of plasma cell dyscrasias (PCD). Limited data exists on FLC clinical specificity in patients diagnosed with other conditions.

Methods
We assessed the κ, λ, and κ/λ FLC ratio using the FreeLite assay and the Sebia FLC ELISA assay in 176 patients with clinical presentations of fatigue, anemia, polyclonal hypergammaglobulinemia, joint disorders, kidney disease and non PCD-cancers with no monoclonal protein observed on serum protein electrophoresis or MASS-FIX immunoglobulin isotyping. Manufacturer defined reference intervals (RI) and glomerular filtration rate (GFR) specific RI (renal RI) were utilized.

Results
For the κ/λ ratio, 68.7 % (121/176) of specimens on the FreeLite and 87.5 % (154/176) of specimens on the Sebia assay were within RI. For κ, 68.2 % (120/176) and 72.2 % (127/176) of results were outside RI for FreeLite and Sebia respectively. For λ, 37.5 % (66/176) and 84.1 % (148/176) of FreeLite and Sebia results were outside RI. With FreeLite and Sebia, patients with kidney disease (n=25) had the highest κ/λ ratios. 44 patients (25.0 %) had GFR <60 mL/min/BSA. When renal RI were applied, 13.6 % had a FLCr outside the renal RI with FreeLite, and 4.5 % with Sebia.

Conclusions
In a cohort of patients with signs and symptoms suggestive of PCDs, but ultimately diagnosed with other conditions, Sebia FLC had improved clinical specificity relative to FreeLite, if one was using an abnormal κ/λ ratio as a surrogate for monoclonality.
Analyse der webbasierten Kommunikation von Informationen und Verhaltensempfehlungen der Bundesregierung zur Covid-19-Pandemie
Authors: Schaeffer Anja , Yetim Fahri 
Published: December 2023

Zusammenfassung
Die Online-Kommunikation der staatlichen Organe wie der Bundesregierung kommt in Zeiten der Corona-Pandemie eine besondere Relevanz zu, da sie – ihrer Informationspflicht entsprechend – den Bürgern in Krisenzeiten durch verlässliche Informationen und Verhaltensempfehlungen Orientierung geben müssen. Diese Studie analysiert, die Online-Kommunikation von Informationen und Verhaltensempfehlungen der Bundesregierung über ihre Website zur Covid-19-Pandemie, um zu verstehen, wie die Bürger die Informationen, Interaktionsmöglichkeiten mit der Website und Verhaltensempfehlungen wahrnehmen. Zu diesem Zweck wurde eine Online-Befragung durchgeführt, die sich an ausgewählten Kriterien der angemessenen Kommunikation aus einer kommunikationstheoretischen Perspektive orientierte. Die Ergebnisse zeigen, dass die Mehrheit der Befragten die kommunizierten Inhalte, Interaktionen und Verhaltensempfehlungen auf der Website der Bundesregierung gemäß den hier berücksichtigten Kriterien in zufriedenstellendem Maße erfüllt wahrgenommen hat. Aus der Befragung geht zudem hervor, dass bei der Kommunikation von Inhalten und Handlungsempfehlungen ein stärkerer Fokus auf Werte wie Freiheit, Solidarität oder Mitbestimmung gewünscht wird.
Clinical application of circulating tumor cells
Authors: Stoecklein Nikolas H. , Oles Julia , Franken Andre , Neubauer Hans , Terstappen Leon W.M.M. , Neves Rui P.L. 
Published: December 2023

Abstract
This narrative review aims to provide a comprehensive overview of the current state of circulating tumor cell (CTC) analysis and its clinical significance in patients with epithelial cancers. The review explores the advancements in CTC detection methods, their clinical applications, and the challenges that lie ahead. By examining the important research findings in this field, this review offers the reader a solid foundation to understand the evolving landscape of CTC analysis and its potential implications for clinical practice. The comprehensive analysis of CTCs provides valuable insights into tumor biology, treatment response, minimal residual disease detection, and prognostic evaluation. Furthermore, the review highlights the potential of CTCs as a non-invasive biomarker for personalized medicine and the monitoring of treatment efficacy. Despite the progress made in CTC research, several challenges such as standardization, validation, and integration into routine clinical practice remain. The review concludes by discussing future directions and the potential impact of CTC analysis on improving patient outcomes and guiding therapeutic decision-making in epithelial cancers.
Should You Use GARCH Models for Forecasting Volatility? A Comparison to GRU Neural Networks
Authors: Pallotta Alberto , Ciciretti Vito 
Published: December 2023

Abstract
The GARCH model is the most used technique for forecasting conditional volatility. However, the nearly integrated behaviour of the conditional variance originates from structural changes which are not accounted for by standard GARCH models. We compare the forecasting performance of the GARCH model to three regime switching models: namely, the Markov Switching GARCH, the Hidden Markov Model, and the Gated Recurrent Unit neural network. We define the number of optimal states by means of three methods: piecewise linear regression, Baum–Welch algorithm and Markov Chain Monte Carlo. Since forecasting volatility models face the bias-variance trade-off, we compare their out-of-sample forecasting performance via a walk-forward methodology. Moreover, we provide a robustness check for the results by applying k-fold cross-validation to the original time series. The Gated Recurrent Unit network is the best suited for volatility forecasting, while the Hidden Markov Model is the best at discerning the market regimes.
Von toxischen Substanzen und toxischer Männlichkeit. Eine korpuspragmatische Studie zur Erschließung eines Gegenwartsphänomens
Authors: Hoffmeister Toke 
Published: December 2023

Abstract
This article deals with the phenomenon of labeling something as toxic. In social media, one often reads about toxic masculinity or toxic relationships and the like. Therefore, the question is addressed whether this is a singular phenomenon for social media or whether labeling something as toxic also affects other domains. First, the historical development since the 19th century is outlined. Then, the DWDS newspaper and reference corpus is evaluated based on a corpus-pragmatic methodology to break down the dimensions of meaning and usage in the context of different usage domains. The end result is thus a comprehensive analysis of writing about toxicity and its metaphorizations, which is finally interpreted and understood as a contemporary phenomenon.
Zweitspracherwerb der präpositionalen Kasusrektion albanischsprachiger DaZ-Lerner
Authors: Selmani Lirim 
Published: December 2023

Abstract
The present article examines the second language acquisition of prepositional case in German by primary school children whose first language is Albanian. I have conducted an experiment in which I examined how case within PPs is acquired and used. My study shows that the children have difficulties regarding the prepositional case marking. There is no difference between the error rate of prepositional accusative and dative. Furthermore, there is no difference among the case markings of the two-way prepositions which appears semantically driven in German with dative and accusative and the one-way prepositions which appears either with the dative or accusative. It will be argued that the morphological opacity within nominal phrases as parts of prepositional phrases in German makes the acquisition of prepositional case system difficult.
Mental Health of Nurses Employed in Surgical and Non-invasive Treatment Wards
Authors: Skuzińska Anna 
Published: December 2023

Introduction. The nursing profession requires employees to be highly resistant to stress. Assisting patients in their experience of pain, illness, helplessness is a stressful experience can be a traumatic experience especially in the face of an immediate threat to a patient’s life. Nursing staff working in treatment wards is exposed to particularly intense stress, in contact with a patient experiencing fear of a surgery and a patient after a surgery experiencing postoperative pain and requiring specialist care.
Aim. The exploratory goal of the study was to diagnose the level of mental health in case of the nurses working in two types of wards: surgical and non-invasive treatment ones. The nurses working in hospital non-invasive treatment wards were expected to have better mental health than the ones working in treatment units.
Material and Methods. An anonymous questionnaire survey was conducted among N=244 nurses of randomly selected hospital wards in a district town in the north of Poland. In the study there were used: General Health Questionnaire GHQ-28 by D. Goldberg and Life Satisfaction Scale by E. Diener and co-workers.
Results. Contrary to the expectations, nurses from non-invasive treatment wards experienced stronger anxiety, insomnia, social dysfunction and lower life satisfaction than their colleagues from surgical units.
Conclusions. Counter to the intuitively imposing image of the work of a nurse in various types of hospital wards, professional burden and mental condition, the need for mental health prevention of nursing staff applies primarily to staff employed in non-invasive treatment wards. With the aging of the population, it is becoming increasingly important to equip these nurses with the skills to cope with prolonged exposure to occupational stressors. (JNNN 2023;12(2):69–73)