bluuebunny/crossref_metadata_2025_split huggingface dataset:
Multi‑scale Experimental Investigations on the Deterioration Mechanism of Sandstone after high-temperature treatment
Authors: Zhang Na , Song Yu , Ren Yuxin , Zhang Piaopiao , Zhang Ziyun , Wang Shuaidong 
Published: December 2023

Abstract
With the continuous construction and development of deep engineering, in order to study the macro-damage and micro-change of temperature on sandstone, this paper conducts a series of Uniaxial Compressive Strength (UCS) tests, Acoustic Emission (AE) monitoring and Nuclear Magnetic Resonance (NMR) experiments on white sandstone treated at 25℃, 100℃, 300℃, 500℃ and 700℃. The study shows that the peak stress of the white sandstone specimens decreases with increasing temperature, and the corresponding axial strain increases significantly. The decrease in uniaxial compressive strength and modulus of elasticity increased sharply. The brittle-ductile transition occurs at about occurs between 500°C ~ 700°C. At temperatures between 25°C and 500°C, the peak AE energy occurs near the peak strength of the sandstone. The ringing counts of the sandstone specimens reached a maximum after the peak stress when the temperature was 700°C, and the peak AE energy gradually decreased at higher heating temperatures. The T2 spectrum curve and pore size curve of the white sandstone increased and gradually shifted to the right with the increase of the treatment temperature, and the total area of the T2 spectrum and porosity also gradually increased. There is a negative correlation between porosity and total area of T2 spectrum and peak stress and elastic modulus of white sandstone under high temperature. The micropores showed a monotonically decreasing trend with increasing temperature, the mesopores showed a trend of decreasing, then increasing, and finally decreasing, and the macropores-cracks enlarged the most.
Design, implementation and validation of a web platform aimed at comparatively evaluating different methods of analgesia for patients undergoing thoracic surgery
Authors: Trò Rosella , Orecchia Angelica , Disma Nicola , Uva Paolo , Cavanna Roberto , Zanardi Nicolò , Torre Michele , Fato Marco Massimo 
Published: December 2023

Abstract
Purpose
This study presents the implementation of a web and mobile application within a clinical trial at Giannina Gaslini Children’s Hospital, aimed at simplifying questionnaire completion for Pectus Excavatum condition, including medical history, preoperative, postoperative, and follow-up evaluations. The ultimate aim focuses on enhancing data collection efficiency, reducing errors, and improving patient engagement within a digital healthcare framework.
Methods
The approach involved careful design based on clinician input, resulting in an intuitive application structure with three main screens. XTENS managed data, and Ionic facilitated cross-platform app development, ensuring secure and adaptable data handling.
Results
Preliminary analysis showcased successful patient enrollment, balanced representation across treatment groups and genders. Notably, cryoanalgesia demonstrated significantly reduced hospitalization days compared to standard therapy, validating treatment efficacy.
Conclusion
This work signifies a step towards modernizing healthcare through digital transformation and patient-centered models. The application shows promise in streamlined data collection and patient engagement, although improvements in multilingual support, data validation, and incentivizing questionnaire completion are warranted. Overall, this study highlights the potential of digital health solutions in revolutionizing healthcare practices, fostering patient involvement, and improving care quality.
Blueprinting the Future: Automatic Item Categorization using Hierarchical Zero-Shot and Few-Shot Classifiers
Authors: Wang Ting , Stelter Keith , Floyd Jenn , O’Neill Thomas , Hendrix Nathaniel , Bazemore Andrew , Rode Kevin , Newton Warren 
Published: December 2023

Abstract
In testing industry, precise item categorization is pivotal to align exam questions with the designated content domains outlined in the assessment blueprint. Traditional methods either entail manual classification, which is laborious and error-prone, or utilize machine learning requiring extensive training data, often leading to model underfit or overfit issues. This study unveils a novel approach employing the zero-shot and few-shot Generative Pretrained Transformer (GPT) classifier for hierarchical item categorization, minimizing the necessity for training data, and instead, leveraging human-like language descriptions to define categories. Through a structured python dictionary, the hierarchical nature of examination blueprints is navigated seamlessly, allowing for a tiered classification of items across multiple levels. An initial simulation with artificial data demonstrates the efficacy of this method, achieving an average accuracy of 92.91% measured by the F1 score. This method was further applied to real exam items from the 2022 In-Training Examination (ITE) conducted by the American Board of Family Medicine (ABFM), reclassifying 200 items according to a newly formulated blueprint swiftly in 15 minutes, a task that traditionally could span several days among editors and physicians. This innovative approach not only drastically cuts down classification time but also ensures a consistent, principle-driven categorization, minimizing human biases and discrepancies. The ability to refine classifications by adjusting definitions adds to its robustness and sustainability.
The impacts of inter- and intra-seasonal burns on the terrestrial orchid Pterostylis curta
Authors: Thomsen Alexandria M. , Davies Richard J. P. , Ooi Mark K. J. 
Published: December 2023

Abstract

Prescribed burning is a management tool used for both management of fuel loads and for ecological purposes across fire prone areas. While in temperate areas wildfires usually occur during the hottest summer months, prescribed burns are generally conducted in autumn and spring to reduce risk. Plant species such as orchids are adapted to summer fires and maintain avoidance mechanisms, such as persisting as dormant tubers during the predominant fire season, and therefore may be at risk from prescribed burns occurring during their active life cycle period. Using a glasshouse experiment, we investigated the impacts of fire season on the Australian orchid species Pterostylis curta. This approach allowed us to i) implement seasonal burns and relate impacts to quantifiable life cycle stages of the study species, ii) isolate and assess the role of smoke, and iii) control for life stage of the study species at each of the treatment levels to enable robust comparison. We found that late autumn burns caused complete failure of a cohort in our glasshouse study. Another key finding is that heat alone is not the driver of tuber mortality, because soil heating was similar across all burn seasons, and plants burnt in the three other seasons were able to resprout strongly in the first growing season after fire. Generally, burning orchids like P. curta at the latter stages of their growing season seems to have low risk, while burning at the start of the growing season is of greater risk but potentially with minimal negative impacts.
Spatial delineation of soil erosion vulnerability in Angereb watershed, Amhara Region, Ethiopia
Authors: TESHOME SAMUEL 
Published: December 2023

Abstract
Background: Soil erosion has always been one of the most severe problems challenging watersheds around the world, mostly in Ethiopia. It is the major type of land degradation, resulting from a combination of natural and human activities.
The main purpose of this research is to demarcate a soil erosion-vulnerable area for watershed planning and conservation plans in study area. In order to map erosion hotspot areas multi-criteria decision analysis (MCDA) technique combined with GIS was used. Based on a conversation with local specialists, as well as the topography of the area and the physical and chemical characteristics of the soil types found in the study area, six major factors: and use, soil, slope, rainfall, Topographic Wetness Index (TWI), and Stream Power Index (SPI) were considered. Each factor was reclassified based on sensitivity classes. These reclassified factors overlaid using the ArcGIS 10.7 weighted overlay analysis tool and produce the final soil erosion source area map of study area.
Results: The final findings indicated that 11.18% of the entire watershed area was highly sensitive, 82.93% was moderately sensitive, 4.64% was low, and 1.25% was very susceptible to soil erosion.
Conclusion: Based on these findings, we can conclude that the majority of the investigated region was moderate to high risk, and most of the soil erosion-susceptible areas were found in the northern, eastern, and north-eastern parts of the watershed, which need suitable plans to conserve water and soil to reduce the disturbing issue of soil loss.
Optimization of Alginate Extraction From Dictyota Mertensii From a Central Composite Design Associated With Response Surface Methodology: Characterization and Antioxidant Potential
Authors: Queiroz Luiz Paulo Oliveira , Aroucha Edna Maria Mendes , Santos Francisco Klebson Gomes dos , Leite Ricardo Henrique Lima 
Published: December 2023

Abstract
This paper extracts alginate of Dictyota mertensii (DM), brown macroalgae found on the north coast of northeastern Brazil. A Composite Central Design (CCD) associated with Response Surface Methodology (RSM) was employed to optimize the extraction process of different fractions of alginate, in different conditions of time, temperature, and concentration of Na2CO3. Yield (𝜂), sulfate content, intrinsic viscosity ([𝜂]), viscosimetric molar mass (Mv), color parameters (a*, b* e L*), and M/G ratio are model response variables. The DM algae has its chemical composition expressed. Response surfaces are plotted from the variables studied, quadratic models were predicted, the influence of factors is analyzed, and response variables are subjected to analysis of variance (ANOVA) and F-test at 95% confidence. The antioxidant potential was evaluated based on the scavenging of the stable free radical 1,1-diphenyl-2-picrylhydrazyl (DPPH). The maximum extraction yield was 29.28±0.02 %, and sulfate content ranged from 3.50±0,00 % to 12.33±0.29 %. The maximum values of [𝜂] and Mv were 5.84±0.06 dL.g-1 and 278.00±2.66 kDa, respectively. The alginate showed a dark brown color and M/G ratio <1, indicating that the extracted alginate provides rigid and compact gels. The antioxidant potential and the CI50 were 54.93±0.27% and 0.51±0.07 mg.mL-1 , respectively, indicating moderate antioxidant activity.
Chatbot for social needs screening and resource sharing with vulnerable families: Iterative design and evaluation study
Authors: Sezgin Emre , Kocaballi A. Baki , Dolce Millie , Skeens Micah , Militello Lisa , Huang Yungui , Stevens Jack , Kemper Alex R. 
Published: December 2023

Abstract

Health outcomes are significantly influenced by unmet social needs. Although screening for unmet social needs has become common in healthcare settings, there is often poor linkage to resources after needs are identified. The structural barriers (e.g., staffing, time, space) to helping address social needs could be overcome by a technology-based solution. This study presents the design and evaluation of a chatbot, DAPHNE©, that screens for social needs and links patients to resources. This study used a two-step approach: (1) iterative design with interdisciplinary stakeholder groups and (2) feasibility and usability assessment. Virtual sessions were held with an interdisciplinary group of stakeholders (n=10) using thematic and content analysis to inform the chatbot's design and development. Evaluation included an online survey, focus group interviews, and scenario-based usability testing with community health workers (family advocates) (n=4) and social workers (n=9). The stakeholders emphasized the importance of provider-technology collaboration, inclusive conversational design, and user education. Users found the chatbot's capabilities met expectations and the chatbot was easy to use (System Usability Scale score=72). The stakeholders raised concerns about accuracy of suggested resources, electronic health record integration, and trust with a chatbot. Future research should examine effectiveness, cost- effectiveness, and scalability of chatbot interventions to address social needs.
Adsorption removal of copper (II) and chromium (VI) from wastewater by Fe3O4-loaded granular activated carbon
Authors: Su Qing , Zhang Jin , Wang Xiaomeng , Li Yuxia , Lin Shuang , Han Jianbo 
Published: December 2023

Abstract

Combining with the characteristics of Fe3O4 and activated carbon, magnetic granular activated carbon (GAC–Fe3O4) was prepared by chemical coprecipitation. With GAC–Fe3O4 as the adsorbent, the effects of GAC–Fe3O4 dosage, the initial pH of wastewater temperature, and the initial concentration of copper (II) and chromium (Ⅵ) on the removal performance were explored. The adsorption process of copper (II) and chromium (VI) on magnetic GAC was studied using adsorption kinetics, adsorption isotherms, scanning electron microscopy, and infrared spectroscopy. The experimental results indicate that among these influencing factors, the pH value of wastewater plays a vital role in the removal efficiency. When the pH value was 6 and 2, the initial concentration of copper (II) and chromium (VI) ions was 5 ppm, the optimum removal efficiencies of copper (II) and chromium (VI) were 99.98 and 96.39%, respectively. As to the adsorption mechanism of GAC–Fe3O4, the adsorption of copper (II) and chromium (VI) in wastewater was more consistent with the Langmuir model. The adsorption process in this study can be well explained by the pseudo-second-order kinetic model.
Analysis of a simplified approach for the determination of modified Kostiakov model parameters
Authors: Zakwan Mohammad 
Published: December 2023

AbstractAccurate estimation of infiltration losses is very important in many hydrologic projects. However, the lack of available data often forces hydrologists to resort to the application of empirical and semi-empirical models for estimating the infiltration rates. Estimation of infiltration rate from these empirical and semi-empirical models is highly dependent on the method adopted to determine the parameters of models. One of the most common infiltration models known as the Kostiakov model was modified to rectify zero infiltration at the start of the infiltration process. Recently, a simplified approach for determining the parameters of the modified Kostiakov model was proposed. The present article focuses on analyzing the reliability of the simplified approach for determining the parameters of the modified Kostiakov model. In this regard, six observed datasets were analyzed from different parts of the world to arrive at some generalized results on the reliability of the simplified approach. Cumulative infiltration obtained from simplified approaches was compared with that obtained through the application of an excel spreadsheet-based nonlinear optimization solver. It was found that on average Sum of Square of Error reduced by 72% on application of nonlinear optimization as compared to the simplified approach.
Childhood Heart Tumors: Detection, Diagnosis, and Treatments
Authors: Jayaraman Megala , Sivakumar Diveyaa 
Published: December 2023

:
Childhood cardiac tumors are rare but challenging conditions that can have a significant
impact on a child’s health and even be fatal if not detected and diagnosed timely. While various types
of tumors can occur in the heart, the most common among children are benign tumors, such as
rhabdomyomas. Diagnosis of pediatric cardiac tumors is often challenging and requires a
combination of clinical examination, imaging studies and biopsy. In some cases, the tumors may be
asymptomatic and discovered incidentally, while in others, they can cause symptoms, such as
shortness of breath, chest pain, arrhythmias and congestive heart failure. Treatment options for
pediatric cardiac tumors vary depending on the type, size and location of the tumor and may include
surgical resection, watchful waiting or a combination of both. The prognosis for children with cardiac
tumors is generally good, with a high rate of complete cure in many cases. However, long-term
follow-up and monitoring are important to detect and manage any potential complications or
recurrence of the tumors.
Epigenetic Modification of HepG2 Cells by Modulating DNA (cytosine-5)-
methyltransferase 1 (DNMT1) and Ten-eleven Translocation Methylcytosine
Dioxygenase 1 (TET1) Expression using Persian Shallot Extract
Authors: Yarahmadi Zahra , Sadeghi Atefeh , Mohammadian Fahimeh , Roustaei Farzad , Hajizadeh Mohammadreza , Mirzaei Mohamamdreza , Swann Jennifer , Hosseiniara Reza , Mahmoodi Mehdi 
Published: December 2023

Background:
Various forms of epigenetic modification, including DNA methylation,
contribute to hepatocellular carcinoma (HCC) dissemination, invasion, and metastasis. The Persian
shallot (Allium hirtifolium Bioss.) is reported to have antibacterial, antifungal, antioxidant, and anticarcinogenic
properties.

Aims:
In the present study, we examined the expression of DNA (cytosine-5)-methyltransferase 1
(DNMT1) and ten-eleven translocation methylcytosine dioxygenase 1 (TET1) at the mRNA level in
HepG2 cells following treatment with Persian shallot extract.

Method:
Ethanolic extracts of Persian shallot were prepared and dried at 80°C and 50°C for 20 and
30 minutes, respectively. Different concentrations of dried shallot extract over the range of 0-250
µg/ml were prepared. HepG2 cells were cultured and the cytotoxicity of each extract concentration
was measured using an MTT assay. The gene expression in treated and untreated cells was assessed
by Real-time polymerase chain reaction (RT-PCR).

Results:
The half maximal inhibitory concentration (IC50) was determined to be 149 µg/ml using an
MTT assay. A concentration of 175 µg/ml was found to reduce the expression of DNMT1 in the
treated group compared to the control group (P<0.001). Furthermore, the TET1 mRNA of HepG2
cells was down-regulated significantly after treatment with 100 and 1000 µg/ml of Persian shallot
extract (P<0.05). These doses reduced the viability of the samples by 60% or higher.

Conclusion:
This study provides evidence for the potential use of Persian shallot extract as a supplementary
herbal agent for the treatment of HCC. The concentrations of extract used in this study
are near or above the level required for toxicity, and as such, further study is warranted.
PRAKIRAAN KEBUTUHAN ENERGI LISTRIK WILAYAH PROVINSI JAWA TENGAH MENGGUNAKAN METODE BACKPROPAGATION NEURAL NETWORK DAN METODE EKSTRAPOLASI LINIER
Authors: Deltania Deva Okky 
Published: December 2023

Kebutuhan energi listrik mengalami peningkatan seiring dengan berjalannya waktu. Faktor-faktor yang mempengaruhi peningkatan tersebut, diantaranya yaitu laju pertumbuhan penduduk, permintaan kebutuhan listrik dalam berbagai sektor seperti rumah tangga, industri, bisnis, social atau public dan juga kenaikan PDRB suatu wilayah. PLN sebagai perusahaan penyedia listrik harus memikirkan hal tersebut agar terjadi keseimbangan supply dan demand. Salah satu cara yang dapat dilakukan oleh PLN yaitu memprakirakan kebutuhan energi listrik di masa yang akan datang. Metode Backpropagation Neural Network (Jaringan Syaraf Tiruan) dan metode Ekstrapolasi Linier digunakan untuk memprakirakan kebutuhan listrik di wilayah Provinsi Jawa Tengah dari tahun 2022-2027. Hasil dari penelitian ini menunjukkan pada metode Backpropagation Neural Network arsitektur jaringan terbaik menggunakan model fungsi pembelajaran LEARNGDM, fungsi pelatihan TRAINGDX dengan 30 neuron yang menghasilkan nilai MAPE atau nilai rata-rata error dengan data aktual PLN terkecil yaitu 8,4%. Sedangkan pada metode Ekstrapolasi Linier prakiraan yang dihasilkan menunjukkan nilai MAPE atau nilai rata-rata error dengan data aktual PLN sebesar 10,7%.
Fly-catching syndrome responsive to a gluten-free diet in a French Bulldog
Authors: Galli Greta , Uccheddu Stefania , Menchetti Marika 
Published: December 2023

Abstract

OBJECTIVE
Fly-catching syndrome (FCS) is a rare condition typically characterized by episodes during which affected dogs bite or lick the air and jump for no apparent reason. Among veterinary literature, obsessive-compulsive disorders, focal epileptic seizures, and underlying gastrointestinal diseases were considered the most likely triggering causes. Recently, gluten-sensitive dyskinesia has been described in dogs, but it has never been reported to be associated to FCS.

ANIMAL
A 6-year-old male French Bulldog.

CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES
The dog was presented for a 2-month history of episodes characterized by sudden onset of jumping while trying to catch something in the air without impaired consciousness or autonomic signs. The episodes could be interrupted by the owner and lasted several minutes. The dog suffered from chronic gastrointestinal signs. The neurological examination was within normal limits except for the episodes suggestive of FCS during the consultation. The serological test for anti-gliadin immunoglobulin G (AG IgG) and anti-transglutaminase-2 immunoglobulin A (ATG-2 IgA) antibodies resulted above the reference range (3.092 and 0.929, respectively; normal range < 0.6).

TREATMENT AND OUTCOME
An exclusively gluten-free diet was started. Complete resolution of the episodes was reported during a 3-month follow-up.

CLINICAL RELEVANCE
To the authors’ knowledge, this is the first report of FCS associated to positive AG IgG and ATG-2 IgA antibodies responsive to a gluten-free diet. The typical manifestation of the episodes and response to diet support the hypothesis that FCS may be associated to gastrointestinal disorders. However, more studies are needed in order to confirm this hypothesis.
Vertical facial pattern and orthodontic stability Part II: Facial axis changes and stability
Authors: Beatrice Mark , Woods Michael 
Published: December 2023

Abstract
Lateral cephalograms and study casts of 55 patients were evaluated to determine if any relationships exist between Facial Axis changes occurring during and after active treatment and either the pretreatment Jarabak Facial Height Quotient or the amount of post-treatment occlusal change, as measured with a weighted PAR score. No significant relationships could be found. There was instead a wide range of individual variation in the post-treatment behaviour of both the Facial Axis and the weighted PAR score, in both the total sample and three Jarabak Facial Height subgroups. Long-term Facial Axis changes occurring in individual patients, however, were not necessarily associated with occlusal deterioration. Since the Facial Axis is likely to change to some extent in the long-term, it was suggested that widely recommended methods for Facial Axis control during treatment should be considered primarily for functional and aesthetic reasons, rather than on the basis of directly ensuring long-term occlusal stability.