bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Dynamic Buffering of Social Support on Depressive Symptoms and Cancer Worries in Patients Seeking Cancer Genetic Counseling
Authors: Ho Sally , Palka Jayme M. , Mersch Jacqueline , Martin W. Blake , Howe-Martin Laura 
Published: January 2024

Abstract
Purpose: Social support is a crucial protective factor against psychological concerns in patients with cancer. However, there is limited knowledge regarding the differential impacts of social support on cancer worries and depressive symptoms in patients undergoing genetic counseling for hereditary cancer. The current study utilized a high-volume database from a multi-site cancer genetics clinic to assess the impact of perceived social support on depressive symptoms and cancer worries among patients of different age groups (young versus older patients) and diagnosis status (diagnosed survivors versus undiagnosed).
Methods: 6,666 patients completed brief assessments of depressive symptoms, cancer worries, social support, and demographic questionnaires as part of routine clinical care between October 2016 and October 2020. Logistics and moderated regression were used to analyze the relationships between social support, depressive symptoms, and cancer worries.
Results: Increased social support was associated with fewer depressive symptoms and fewer cancer worries across all patients. Social support mitigated depressive symptoms most significantly for young adult patients with and without cancer. Social support mitigated cancer worries most significantly for young adults with cancer and older adults without cancer.
Conclusions While results were mixed, general findings upheld original hypotheses. Social support buffered depressive symptoms and cancer worries differentially for patients of different ages and different disease status.
Implications for Cancer Survivors: Social support groups are beneficial for all patients and should be emphasized by cancer clinics. However, increasing patient-tailored and age-appropriate support networks will be crucial for managing depression and cancer worries for high-risk survivors: young adults with cancer.
The Soret Effect in Laser Chemical Vapor Deposited Fibers
Authors: Cook Charles A. , Fronk Kenan , Thompson Gregory B 
Published: January 2024

Abstract

Laser Chemical Vapor Deposition (LCVD) is the process by which free standing fibers additively deposit from the gas-to-solid phase under a laser focal point. In this letter, we address how the mixing of disparate molecular weight precursors facilitate changes in the growth and fiber structure using the Soret effect. The Soret effect causes lighter particles to migrate to warmer regions and heavier particles to migrate to cooler regions in a reaction. Using ethylene mixed with helium, the reaction rate, temperature, activation energy, and morphology for a series of carbon fibers are compared. It was found that the onset of the Soret effect bypasses specific growth regimes, reduces the extent of graphitization, and creates morphological variations within the fiber core. These results highlight the potential use of the Soret effect as a new means of tailoring LCVD fiber processing.
Maglev-fabricated long and biodegradable stent for interventional treatment of peripheral vessels
Authors: Ding Jiandong , Zhang Wanqian , Gao Xian , Zhang Hongjie , Sun Guoyi , Zhang Gui , Li Xin , Qi Haiping , Guo Jingzhen , Qin Li , Shi Daokun , Shi Xiaoli , Li Haifeng , Zhang D.Y. , Guo Wei 
Published: January 2024

Abstract

While chronic limb-threatening ischemia is a serious peripheral artery disease, the lack of an appropriate stent significantly limits the potential of interventional treatment. In spite of much progress in coronary stents, little is towards peripheral stents, which are expected to be long and biodegradable and thus require more breakthroughs in core techniques. Herein, we develop a long & biodegradable stent (LBS) with a length of up to 118 mm based on a metal-polymer composite material. Nitriding treated iron with elevated mechanical performance was applied as the skeleton of the stent, and a polylactide coating was used to accelerate iron degradation. To achieve a well-prepared homogeneous coating on a long stent during ultrasonic spraying, a magnetic levitation (Maglev) was employed. In vivo degradation of the LBS was investigated in rabbit abdominal aorta/iliac arteries, and preclinical safety and efficacy were evaluated in canine infrapopliteal arteries. First-in-man implantation of LBS was carried out in the below-the-knee artery, and the 6–13 months follow-ups demonstrated the feasibility of the first LBS.
Predicting the Effect of Hydro-Climatic and Land-Use Dynamic Variables on Watershed Health Status
Authors: Rajabi Mohammadrasoul , Vafakhah Mehdi , Sadeghi Seyed Hamidreza 
Published: January 2024

Abstract

This study was conducted with the objectives of predicting the effect of changing hydro-climatic variables, predicting the effect of land-use change on the future health status of the Safa-Roud Watershed, and the role of hydro-climatic and land-use variables in the spatial prioritization of sub-watersheds based on watershed health index. To conduct this study, first, key characteristics were extracted based on human, climatic, and hydrological factors for all three indicators of pressure, state, and response. Then, the watershed health index was calculated for the current conditions. After that, watershed health was predicted based on dynamic hydro-climatic and land-use variables for the 10 and 20 years ahead. The health assessment and zoning of the Safa-Roud Watershed showed that the average value and standard deviation of the current pressure index were equal to 0.573 and 0.185, respectively. The lowest value of this index was around 0.290 and related to sub-watershed 5, and the highest value was around 0.840 and related to sub-watershed 11. The initial evaluation of the classification indicated the prevalence of moderate and high-pressure conditions with a range of about 79%. Finally, the physical factors of sub-watersheds (time of concentration with 15.72%) had the most minor role. In general, among the criteria used to calculate the pressure index in the current period, human factors and climatic factors showed the highest percentage of participation in determining the pressure index. The quantification of the current watershed health status and the 10- and 20-year forecast periods showed that the values of the watershed health index were similar. However, the changes in the health index in the sub-watersheds at the beginning of the study period ranged from relatively unhealthy favorable conditions to moderately positive and moderately negative conditions.
Comparative Study of Traditional vs. Digital Learning Materials in Ghanaian Schools
Authors: Atuahene Samspon , Xu Qian , Bentum-Micah Goeffrey 
Published: January 2024

Abstract
This paper examines the escalating concerns within the Ghanaian educational sector, particularly in primary and secondary education. It delves into the influence of rapidly evolving scientific and technological landscapes and their impact on educational quality. A specific focus is placed on the critical role of textbook selection, mainly electronic textbooks, in enhancing students' academic performance. A quasi-experimental study targeted the efficacy of e-textbook selection in a mathematics curriculum among fifth-grade students in a Ghanaian primary school. The rapid advancement in technology and its integration into educational methodologies has prompted a reevaluation of traditional teaching resources, mainly textbooks. In Ghana, this paradigm shift has sparked an interest in understanding how these changes impact student learning outcomes. The selection of appropriate educational materials, especially in foundational subjects like mathematics, is crucial in this digital era. The study employed a quasi-experimental design involving 280 fifth-grade students from a primary school in Ghana. These students, with an average age of nine, were divided into two groups, each using a different type of e-textbook for mathematics learning. The research methodology was designed to measure the impact of these textbooks on student performance quantitatively. The ANCOVA analysis of the data indicated a notable difference in the academic performance between the two groups. The second type of e-textbook group demonstrated a higher average score of 72.75 in the assessment, compared to 66.58 in the first group. This difference (F = 9.34, p < 0.05) was statistically significant, suggesting the choice of e-textbook plays a vital role in academic achievement. The findings suggest that selecting e-textbooks is critical in enhancing student learning outcomes. The study also provides educators with valuable criteria for selecting high-quality e-textbooks. These criteria, grounded in theoretical and empirical research, can significantly influence the educational process and outcomes. This research highlights the potential of e-textbooks to transform educational experiences and outcomes in primary education, particularly in mathematics. It underscores the need to carefully select digital educational resources based on robust educational theories and quality indicators. The implications of this study are significant for educators and policymakers in the Ghanaian education system as they navigate the integration of technology in teaching and learning processes.
A Comprehensive Framework for Evaluating and Predicting Investment Risks in Renewable Energy Projects: A Case Study of Maynak Hydropower Station
Authors: Xu Nanjie , Wan Anxia , Li Yue , Elahi Ehsan , Peng Benhong 
Published: January 2024

Abstract
This study introduces a holistic analysis framework designed to evaluate and predict the investment risks associated with foreign renewable energy initiatives. The primary objective of this framework is to address the inherent uncertainties that often accompany such projects. To achieve this, we employ the variable weight matter-element extension model to establish the project's fundamental reliability function. Subsequently, we enhance this model using evidence theory to determine the project's risk level and generate risk index measurement results. Additionally, we utilize the GM model for forecasting future project risks. To illustrate the practicality of our approach, we provide a case study focused on the risk assessment and prediction for the Maynak Hydropower Station. Our findings indicate that during 2008, 2014, 2020, and 2022, the project faced a high level of investment risk. Key risk indicators included political instability, policy changes, legislative gaps, cultural risks, exchange rate fluctuations, technical challenges, and management risks. Moreover, from 2023 to 2027, the project's investment risk level moderated, with risk measurement results aligning closely with actual circumstances, thus validating the efficacy and applicability of our model.
Capturing ring opening in photoexcited enolic acetylacetone upon hydrogen bond dissociation by ultrafast electron diffraction
Authors: Leone Stephen , Scutelnic Valeriu , Tikhonov Denis , Poullain Sonia Marggi , Haugen Eric , Attar Andrew , Barreau Lou , Chang Kristina , Fidler Ashley , Gaynor James , Lin Yen-Cheng , Yang Jie , Champenois Elio , Wang Xijie , Shen Xiaozhe , Luo Duan , Ji Fuhao , Weathersby Stephen , Vishnevsky Yury , Schnell Melanie , Wolf Thomas , Lin Ming-Fu 
Published: January 2024

Abstract

Photoinduced biological and chemical reactions are often based on key structural transformations of a molecule driven across multiple electronic states. Acetylacetone (AcAc) is a prototypical system for complex chemical pathways involving several conical intersections (CI) and singlet-triplet intersystem crossings (ISC) characterized by distinct geometries. In the gas phase, AcAc is predominantly in a planar ring-like enolic form stabilized by a strong intramolecular O-H∙∙∙O hydrogen bond. Following excitation into the S2 (ππ*) state at 266 nm, acetylacetone undergoes rapid internal conversion followed by intersystem crossing. Such relaxation pathways are associated with structural changes including ring opening, deplanarization and bond elongation. In this work, ultrafast electron diffraction (UED) at the SLAC MeV-UED setup is employed as a direct structural probe with a time resolution of 160 fs. Together with trajectory surface hopping simulations, analysis of the UED data provides a new perspective on the early time nuclear dynamics in acetylacetone. Specifically, AcAc is observed to undergo ring opening, deplanarization and bond elongation all within the first 700 fs after photoexcitation. The monitored dynamics is associated mainly with the nuclear motion on the S1 potential energy surface, formed after very rapid transfer from S2 to S1, allowing AcAc to reach the conical intersection to intersystem crossing. Such timescales of nuclear motion are contrasted with the timescales of electronic transitions in AcAc that were previously characterized with spectroscopic methods, specifically internal conversion (<100 fs) and intersystem crossing (≈ 1.5 ps).
Robust Mendelian Randomization Analysis by Automatically Selecting
Valid Genetic Instruments with Applications to Identify Plasma Protein Biomarkers for Alzheimer’s Disease
Authors: Liu Zhonghua , Yao Minhao , Miller Gary , Vardarajan Badri , Baccarelli Andrea , Guo Zijian 
Published: January 2024

Abstract
Mendelian randomization (MR) uses genetic variants as instrumental variables (IVs) to infer the causal effect of a modifiable exposure on the outcome of interest by removing unmeasured confounding bias. However, some genetic variants might be invalid IVs due to violations of core IV assumptions. MR analysis with invalid IVs might lead to biased causal effect estimate and misleading scientific conclusions. To address this challenge, we propose a novel MR method that first Selects valid genetic IVs and then performs Post-selection Inference (MR-SPI) based on two-sample genome-wide summary statistics. We analyze 912 plasma proteins using the large-scale UK Biobank proteomics data in 54,306 participants and identify 7 proteins (TREM2, PILRB, PILRA,
EPHA1, CD33, RET, CD55) significantly associated with the risk of Alzheimer's disease. We employ AlphaFold2 to predict the 3D structural alterations of these 7 proteins due to missense genetic variations, providing new insights into their biological
functions in disease etiology.
Effects of Climatic Factors on the Intraocular Pressure in Normal Eyes under Everyday Conditions
Authors: Ikushima Toru , Iwase Aiko , Murata Hiroshi , Ueno Morio , Mori Kazuhiko , Ikeda Yoko , Mieno Hiroki , Sotozono Chie , Kinoshita Shigeru , Yamamoto Tetsuya , Araie Makoto 
Published: January 2024

Abstract
Background/Objectives:Little is known about effects of climatic factors on intraocular pressure (IOP) in normal eyes. The purpose of this study is to investigate correlation between climatic factors and Goldmann applanation tonometer-measured IOP (GAT-IOP) in normal eyes under everyday conditions.
Subjects/Methods: Data from 2,341 normal eyes 2,341 subjects; mean age, 56.9 years) who participated in a population-based glaucoma survey in Japan were analyzed using the multivariable regression analysis, in which the GAT-IOP was the response variable; explanatory variables were the hourly time of day and day of the week/month when each subject was examined, ocular and systemic factors reportedly correlated with GAT-IOP and ambient atmospheric pressure (AP), relative humidity (RH), temperature, wind speed, amount of precipitation, and weather.
Results: The AP of the outside air when each subject was examined and the average AP and RH of the outside air over 24 hours before each subject’s examination were positively (P=0.0001, P=0.0056, P=0.0112, respectively) correlated with the GAT-IOP. The central corneal thickness, body mass index, and systolic blood pressure were positively (P<0.0001, P=0.0001, P=0.0007, respectively), corneal curvature radius and age were negatively (P=0.0168, P=0.0056, respectively) correlated with the GAT-IOP. The GAT-IOP measured on various days of the week and months fluctuated significantly (P<0.0001).
Conclusions:After adjusting for the effects of other possibly confounding factors, the GAT-IOP was significantly positively correlated with ambient AP and RH in normal eyes under everyday conditions. The effects of systemic, ocular factors and month on the GAT-IOP obtained were compatible with those previously reported.
Estimation of the size, density, and demographic distribution of the UK pet dog population
Authors: McMillan Kirsten M , Harrison Xavier A , Upjohn Melissa M , Christley Robert M , Casey Rachel A 
Published: January 2024

Abstract

There is limited knowledge about the size of the UK dog population. This makes it difficult to reliably monitor changes in overall population size and characteristics, or the dynamics of dog supply and movement. A repeatable method of measuring the UK dog population would help inform interventions to reduce risks to dog welfare such as poor breeding practices and the illegal import of young or pregnant dogs. However, estimating the total dog population in the UK is not straightforward. Although several estimates of dog numbers have been previously suggested, differing methodologies and limited public access to data sources makes comparison and replication difficult.
In this study, we compiled a comprehensive dataset of UK pet dogs from multiple sources, including breed registries, veterinary corporations, pet insurance companies, animal welfare charities, and academic institutions. Using a hierarchical Bayesian N-mixture model, we estimate 12.64 million (95% CI 8.54-15.16 million) pet dogs within the UK in 2019. Estimates were modelled at the postcode area scale, allowing for aggregation to region or country level, as well as providing associated metrics of uncertainty. Furthermore, we provide spatial demographic estimates, regarding age, breed, cephalic index, and body size.
Establishing a population baseline offers significant analytical benefits to welfare, veterinary, epidemiological, and business stakeholders alike: as it provides the spatial data required to underpin robust canine welfare strategies and campaigns.
Obtaining Optimum Cutting Parameters of Carbon Fiber Reinforced Polymer Composite (CFRP) Material by Using GA and SA Methods during Drilling
Authors: Gultekin Mehmet Sah , Isik Birhan , Jun Martin Byung-Guk 
Published: January 2024

Abstract
This paper presented a new comprehensive approach to select cutting parameters for surface roughness in drilling of carbonfiber reinforced polymer composite (CFRP) material. The influence of drilling on surface quality of woven CFRP materials was investigated experimentally. The CFRP material (0/90° fiber orientation) was drilled at different cutting parameters and the surface roughness of the hole was measured. Drilling tests were carried out using carbide drills of 8 mm in diameter at 50, 70, and 90 m/min cutting speeds; 2, 3 and 4 flute numbers and 0.2, 0.3, and 0.4 mm/rev feed rates. Simulated Annealing (SA) and Genetic Algorithm (GA) methods were used for optimization. According to the results of the experimental study and optimization technique, optimum cutting parameters were obtained and started to be changed in order to have the best surface quality.
Integrated nutrient management on oat-grasspea intercropping system: An evaluation of system productivity, economics, energetics and carbon footprint
Authors: Biswas Saikat , Das Rupa , Jana Kalyan , Puste A.M. 
Published: January 2024

Abstract

A field investigation was conducted at Central Research Farm of Bidhan Chandra Krishi Viswavidyalaya, West Bengal, India during winter seasons of 2020-21 and 2021-22 with the aim to evaluate system productivity, economics, energetics and carbon footprint (CF) of oat-grasspea intercropping systems under different integrated nutrient managements (INM). The experiment was laid out in split-plot design with 4 cropping systems in main plots and 4 levels of nutrient management in sub plots. Sole grasspea cultivation stood best in terms of system productivity, economics, energetics and environment safety by low CF. Moreover, INM involving 75% N through urea + rest N through vermicompost registered significantly higher system productivity (15.49 q ha-1) in case of 3:3 oat+ grasspea intercropping system (CS4N3). Further, this intercropping system registered high economic profitability (net return: US$ 430.4 ha-1, B:C- 1.71) as well as energy indices (energy output: 71179.1 MJ ha-1, net energy gain: 60352.0 MJ ha-1, energy ratio: 6.57 and energy profitability: 5.57). CF was also found relatively less under CS4N3 (Yield scaled CF: 75.3 kg CO2-e q-1). High carbon efficiency (7.92) and carbon sustainability index (6.92) were also recorded by CS4N3 as it produced maximum carbon output (1801.2 kg ha-1). Overall, 3:3 oat+ grasspea intercropping system can be cultivated by the cereal and legume growers of India under intensive cropping scenario using 75% N through urea + rest N through vermicompost as INM option.
Theoretical solvent recovery and grafting application in Xinjiang waste PE based on solubility parameters
Authors: wang xin , Yu Shenglong , Li Yuan , Fang Yue , Wang Yifan , yalikun nuerbiya 
Published: January 2024

Abstract
This paper investigates the recovery of waste PE (mulch film) from Xinjiang by solvent recovery method. Under the guidance of solubility parameter theory, combined by HSPiP（version 4.1.07）experiment and HSPs library screening, xylene was selected as the most suitable solvent for recovery of PE. Subsequently, the solid-liquid method was used to graft MAH to PE, and the optimal process conditions were obtained through orthogonal experiments, and the successful grafting of MAH to PE was verified by infrared spectroscopy. Then through XRD and other checks to analyze the PE before and after grafting, MAH did not change the crystal arrangement of PE, nor did it alteration the crystal type, the introduction of MAH enhanced the surface energy of PE and reduced the regularity of the PE structure. The results of DSC showed that after MAH grafting, the nucleation site on the surface of PE increased, which could make the modified PE crystallize rapidly, so that the cold crystallization peak disappeared, and the stability was enhanced, which is of great significance for subsequent asphalt modification.