bluuebunny/crossref_metadata_2025_split huggingface dataset:
PRAMEL7 and CUL2 decrease NuRD stability to establish ground-state pluripotency
Authors: Rupasinghe Meneka , Bersaglieri Cristiana , Leslie Pedrioli Deena M , Pedrioli Patrick GA , Panatta Martina , Hottiger Michael O , Cinelli Paolo , Santoro Raffaella 
Published: February 2024

AbstractPluripotency is established in E4.5 preimplantation epiblast. Embryonic stem cells (ESCs) represent the immortalization of pluripotency, however, their gene expression signature only partially resembles that of developmental ground-state. Induced PRAMEL7 expression, a protein highly expressed in the ICM but lowly expressed in ESCs, reprograms developmentally advanced ESC+serum into ground-state pluripotency by inducing a gene expression signature close to developmental ground-state. However, how PRAMEL7 reprograms gene expression remains elusive. Here we show that PRAMEL7 associates with Cullin2 (CUL2) and this interaction is required to establish ground-state gene expression. PRAMEL7 recruits CUL2 to chromatin and targets regulators of repressive chromatin, including the NuRD complex, for proteasomal degradation. PRAMEL7 antagonizes NuRD-mediated repression of genes implicated in pluripotency by decreasing NuRD stability and promoter association in a CUL2-dependent manner. Our data link proteasome degradation pathways to ground-state gene expression, offering insights to generate in vitro models to reproduce the in vivo ground-state pluripotency.
On multiple handoff blocking‐then‐reaccess for opportunistic spectrum access
Authors: Zhang Jing , Liang Chu‐Long , Gao Hong‐Xu , He Yan , Zhu Hong‐Bo 
Published: February 2024

AbstractOpportunistic spectrum access (OSA), a promising technology to resolve radio spectrum scarcity, is still faced with some challenges, of which one is potentially frequent channel handoff (CH) even handoff blocking (HB) for secondary user (SU) to avoid primary user (PU). Reaccess is a direct way to resolve HB. However, multiple handoff blocking‐then‐reaccess (H‐BTR) are time consuming. Whether it is worthwhile to make multiple H‐BTR, is an interesting but hardly mentioned issue. To this end, the multiple H‐BTR‐based OSA are focused on here. Three key indices, the average transmission probability, handoff delay, and average reaccess times of SU in the H‐BTR‐based OSA, are deduced as close form first. Then, the effects of H‐BTR frequency and service traffic rate of SU on OSA are discussed. Finally, the H‐BTR‐based OSA is compared to two other schemes, the handoff without BTR (HWBTR)‐based OSA and the stop‐and‐waiting (SW)‐based OSA. Theoretical and simulated results show that the H‐BTR‐based OSA performs best among three schemes. Making H‐BTR in moderate frequency according to service traffic rate can increase transmission opportunity while additional delay of SU is tolerable, thus the performance of OSA can be well improved.
Post-COVID in women after SARS-CoV-2 infection during pregnancy
– a pilot study with follow-up data from the COVID-19-related Obstetric
and Neonatal Outcome Study (CRONOS)
Authors: Backes Clara , Pecks Ulrich , Keil Corinna Nora , Zöllkau Janine , Scholz Christoph , Hütten Matthias , Rüdiger Mario , Büchel Johanna , Andresen Kristin , Mand Nadine 
Published: February 2024

Abstract
Background Pregnant women are at an increased risk of severe COVID-19 and
adverse pregnancy outcomes; data on maternal long-term outcome is scarce. We
analyzed long-term follow-ups on women who experienced a SARS-CoV-2 infection
during pregnancy to evaluate post-COVID symptoms, particularly fatigue, and
their association with quality of life (QoL).
Methods 773 women who enrolled in the CRONOS registry between April 2020
and August 2021 were contacted for follow-up from December 2022 to April 2023.
Data was gathered through a web-based questionnaire. Subsequently, study
coordinators matched the follow-up data with the existing CRONOS data.
Results 110/773 (14%) women provided data. 20.9%
experienced only acute symptoms during their SARS-CoV-2 infection in pregnancy,
while 2.7% women experienced symptoms lasting longer than 4 weeks (long
COVID). Symptoms lasting longer than 12 weeks (post-COVID) were reported by
63.6% women and occurred more often after severe COVID-19. Fatigue was
the most frequently reported symptom (88%), with 55% of women
still experiencing it more than one year after initial infection. 76% of
women rated their QoL as “good” or “very good”.
Women experiencing post-COVID reported a significantly lower QoL.
Conclusion This is the first German long-term data on women after
SARS-CoV-2 infection during pregnancy, showing a high rate of post-COVID, a
persistence of fatigue, and the impact on QoL. Continuous monitoring of pregnant
women with COVID-19 is needed to develop comprehensive management
strategies.
Evolution of Fetal Growth in Symptomatic Sars-Cov-2
Pregnancies
Authors: Hachenberg Jens , Guenther Julia , Steinkasserer Lena , Brodowski Lars , Dueppers Ansgard Lena , Delius Maria , Chiaie Loredana Delle , Lobmaier Silvia , Sourouni Marina , Richter Manuela F. , Manz Jula , Parchmann Olaf , Schmidt Saskia , Winkler Jennifer , Werring Pia , Kraft Katrina , Kunze Mirjam , Manz Maike , Eichler Christian , Schaefer Viola , Berghaeuser Martin , Schlembach Dietmar , Seeger Sven , Schäfer-Graf Ute , Kyvernitakis Ioannis , Bohlmann Michael K. , Ramsauer Babette , Morfeld Christine Angela , Ruediger Mario , Pecks Ulrich , von Kaisenberg Constantin 
Published: February 2024

Abstract
Introduction SARS-CoV-2 is a viral disease with potentially devastating
effects. Observational studies of pregnant women infected with SARS-CoV-2 report
an increased risk for FGR. This study utilizes data from a prospective
SARS-CoV-2 registry in pregnancy, investigating the progression of fetuses to
fetal growth restriction (FGR) at birth following maternal SARS-CoV-2 and
evaluating the hypothesis of whether the percentage of SGA at birth is increased
after maternal SARS-CoV-2 taking into account the time interval between
infection and birth.
Materials & Methods CRONOS is a prospective German registry
enrolling pregnant women with confirmed SARS-CoV-2 infection during their
pregnancy. SARS-CoV-2 symptoms, pregnancy- and delivery-specific information
were recorded. The data evaluated in this study range from March 2020 until
August 2021. Women with SARS-CoV-2 were divided into three groups according to
the time of infection/symptoms to delivery: Group I<2 weeks,
Group II 2–4 weeks, and Group III>4 weeks. FGR was defined as
estimated and/or birth weight<10% ile, appropriate for
gestational age (AGA) was within 10 and 90%ile, and large for
gestational age (LGA) was defined as fetal or neonatal
weight>90%ile.
Results Data for a total of 2,650 SARS-CoV-2-positive pregnant women were
available. The analysis was restricted to symptomatic cases that delivered after
24+0 weeks of gestation. Excluding those cases with missing values for
estimated fetal weight at time of infection and/or birth weight centile,
900 datasets remained for analyses. Group I consisted of 551 women, Group II of
112 women, and Group III of 237 women. The percentage of changes from AGA to FGR
did not differ between groups. However, there was a significantly higher rate of
large for gestational age (LGA) newborns at the time of birth compared to the
time of SARS-CoV-2 infection in Group III (p=0.0024), respectively.
Conclusion FGR rates did not differ between symptomatic COVID infections
occurring within 2 weeks and>4 weeks before birth. On the contrary, it
presented a significant increase in LGA pregnancies in Group III. However, in
this study population, an increase in the percentage of LGA may be attributed to
pandemic measures and a reduction in daily activity.
Identification of Patients with Early HR+ HER2− Breast Cancer at High Risk of Recurrence
Authors: Fasching Peter A. , Kreipe Hans , Del Mastro Lucia , Ciruelos Eva , Freyer Gilles , Korfel Agnieszka , Chouaki Nadia , Stoffregen Clemens , Sapunar Francisco , Cameron David 
Published: February 2024

AbstractBreast cancer incidence has increased in the last two decades and, simultaneously, survival has improved due to earlier detection and improved treatment options. Despite this improvement,
locoregional recurrences and distant metastases occur in up to 10 and 30% of women diagnosed with early breast cancer, respectively. Around 70% of breast cancers are hormone receptor
positive (HR+), human epidermal growth factor receptor 2 negative (HER2−), and associated with a persistent risk of relapse up to 20 years after diagnosis/initial treatment. We conducted a
narrative review by combining PubMed searches with our clinical experience to describe patient characteristics, biomarkers, and genomic profiling tools available to clinicians for the
identification of patients with HR+, HER2− early breast cancer at high risk of recurrence and to provide recommendations to classify patients into recurrence risk categories. National and
international treatment guidelines are also summarised. Accurate assessment of the risk of recurrence in these patients is crucial as the predicted risk guides treatment decisions; imprecise
estimations can result in over- or undertreatment, with either scenario having negative consequences for patients. Multiple prognostic tools and factors are recommended for early breast
cancer, and no single test provides accurate prognosis in isolation. Since no single test can provide accurate prognosis in isolation, a combination of tools should be used. Risk thresholds
are important to guide optimised and balanced therapeutic decisions in HR+, HER2− early breast cancer. However, prognostic assessment should be performed on a case-by-case basis, making
patient-specific prognostic approaches essential to avoid over- or undertreatment.
Allelic Variants of the Complement Genes in Acute Postinfectious
Glomerulonephritis
Authors: Leventoğlu Emre , Öğüt Betül , Gönül İpek Işık , Fidan Kibriya , Söylemezoğlu Oğuz 
Published: February 2024

IntroductionAcute postinfectious glomerulonephritis (APIGN) is one of the most common causes of
acute glomerulonephritis in children. It may lead to inflammation and proliferation
of glomerular tissue through immunologic mechanisms (Balasubramanian R, Paediatr Int
Child Health 2017;37:240–247).
Ethnic representation analysis of commercial movie posters
Authors: Kagan Dima , Levy Mor , Fire Michael , Fuhrmann Alpert Galit 
Published: February 2024

AbstractIn the last decades, global awareness toward the importance of diverse representation has been increasing. The lack of diversity and discrimination toward minorities did not skip the film industry. Here, we examine ethnic bias in the film industry through commercial posters, the industry’s primary advertisement medium for decades. Movie posters are designed to establish the viewer’s initial impression. We developed a novel approach for evaluating ethnic bias in the film industry by analyzing nearly 125,000 posters using state-of-the-art deep learning models. Our analysis shows that while ethnic biases still exist, there is a trend of reduction of bias, as seen by several parameters. Particularly in English-speaking movies, the ethnic distribution of characters on posters from the last couple of years is reaching numbers that are approaching the actual ethnic composition of the US population. An automatic approach to monitoring ethnic diversity in the film industry, potentially integrated with financial value, may be of significant use for producers and policymakers.
The role of emotion and social connection during the COVID-19 pandemic phase transitions: a cross-cultural comparison of China and the United States
Authors: Lu Liangdong , Xu Jia , Wei Jiuchang , Shults F. LeRon , Feng Xing Lin 
Published: February 2024

AbstractLeveraging substantial data from China’s Weibo and datasets from Reddit and X (previously Twitter) in the United States, this research explores the disparities and complex dynamics of emotions and social connections among social media users in China and the United States during the COVID-19 pandemic. The findings indicate that the expression of three negative emotions (anxiety, sadness, and anger) and positive emotions exhibited distinctive dynamics under the impact of the pandemic, with China individuals expressing more anxiety but less sadness and anger than those in the US. Moreover, Chinese social media experienced a surge in positive emotional expressions under lockdown, whereas the US witnessed a conspicuous decline in positive emotions. Also, the expression of three types of social connections - “family”, “collective”, and “country”-exhibited significant differences under the impact of the pandemic, with Chinese individuals establishing deeper connections with their country and American individuals leaning towards familial connections. Further analysis on the moderating effects of social connections substantiated that the “country” connection in China and the “family” connection in the US mitigated the negative emotions affected by the pandemic. These findings facilitate a deeper understanding of how cultural contexts shape social and psychological responses in crises. Based on topic analysis and forward-looking orientation analysis, this study dissects the aforementioned findings through the dichotomy of collectivist and individualist cultures, providing new insights for social psychological support and emotional guidance in the development of public health communication strategies in the future.
Exploring patterns of lexical variation in the use of epistemic stance markers in written L2 English across task types and levels of proficiency
Authors: Pyykönen Maria 
Published: February 2024

Abstract
The present study examines the lexical patterning of altogether 4,022 instances of epistemic stance markers (EDs)
across four levels of L2 proficiency (B1–C2) and three types of writing tasks (‘opinion’, ‘complaint’, and ‘letter’) by using the
exploratory technique of Multiple Correspondence Analysis. The data stem from a Finnish learner English corpus,
comprising of 1,773 texts. The results of the study showed that while the lexical patterns of EDs in the data seemed to be mostly
related to task type, some proficiency-related patterns of ED use were observed across all tasks. In some cases,
proficiency-related patterns could also only be observed in some of the tasks, suggesting task type and proficiency are, to some
extent, interrelated when examining the use of EDs. The results thus suggest that both task- and proficiency-related constraints
of EDs should be considered in both foreign language teaching and assessment.
Je dirais / diría yo, analyse contrastive français / espagnol
Authors: Vázquez-Molina Jesús , Donaire María Luisa 
Published: February 2024

Résumé
L’objectif de cette contribution est une étude contrastive de deux entités, je dirais en
français et diría yo en espagnol. La stratégie discursive instruite par le marqueur français je
dirais représente une certaine attitude du locuteur, celui-ci présentant un contenu p, dont il est
la source, comme non partagé par la communauté linguistique. Cette description sémantico-pragmatique trouve sa correspondance en
surface avec des propriétés formelles spécifiques, notamment la position en incise et la combinatoire avec certaines unités
linguistiques. Le marqueur de la langue espagnole admet les mêmes combinaisons que je dirais et présente
d’autres propriétés communes avec ce dernier. Malgré ces quelques ressemblances le comportement sémantico-pragmatique des
deux marqueurs diffère, je dirais mettant l’accent sur le dire, tandis que dans le cas de diría
yo l’accent est mis sur le dit.
“Wouldn’t it be better for me to earn my own money and pay taxes?”
Authors: Lampropoulou Sofia , Johnson Paige 
Published: February 2024

Abstract
This study concentrates on migrant representations in stories posted on the websites of UK charity
organizations. Drawing upon critical discourse analytic and narrative positioning tools, we examine migrant identity
navigation in the past and present that, predominantly, leads to the construction of fulfillment identities.
We discuss the ways in which these positionings promote an ideal migrant norm that contributes to wider national homogenizing
discourses. We view these stories as sites of liquid racism that divide migrants who succeed and are, thus,
fulfilled and migrants who are deviant. We interrogate these representations, given that
charity organizations are committed to providing social assistance to migrants and refugees, thus aligning with humanitarian
and antiracist discourses.
Inverse problem for Love waves in a layered, elastic half-space
Authors: de Hoop Maarten V , Garnier Josselin , Iantchenko Alexei , Ricaud Julien 
Published: February 2024

Abstract
In this paper we study Love waves in a layered, elastic half-space. We first address the direct problem and we characterize the existence of Love waves through the dispersion relation. We then address the inverse problem and we show how to recover the parameters of the elastic medium from the empirical knowledge of the frequency–wavenumber couples of the Love waves.
Influence of temperature on bandgap shifts, optical properties and photovoltaic parameters of GaAs/AlAs and GaAs/AlSb p–n heterojunctions: insights from ab-initio DFT + NEGF studies
Authors: Mamindla Ramesh , Niranjan Manish K 
Published: February 2024

Abstract
The III–V group semiconductors are highly promising absorbers for heterojunctions based solar cell devices due to their high conversion efficiency. In this work, we explore the solar cell properties and the role of electron–phonon coupling (EPC) on the solar cell parameters of GaAs/AlSb and GaAs/AlAs p–n heterojunctions using non-equilibrium Green function method (NEGF) in combination of ab-initio density functional theory (DFT). In addition, the band offsets at the heterointerfaces, optical absorption and bandgap shifts (BGSs) due to temperature are estimated using DFT + NEGF approach. The interface band gaps in heterostructures are found to be lower than bulk band gaps leading to a shift in optical absorption coefficient towards lower energy side that results in stronger photocurrent. The temperature dependent electronic BGS is significantly influenced by the phonon density and phonon energy via EPC. The phonon influenced BGS is found to change the optical absorption, photocurrent density and open-circuit voltage. In case of GaAs/AlSb junction, the interface phonons are found to have significantly higher energies as compared to the bulk phonons and thereby may have important implications for photovoltaic (PV) properties. Overall, the present study reveals the influence of EPC on the optical absorption and PV properties of GaAs/AlSb and GaAs/AlSb p–n heterojunctions. Furthermore, the study shows that the DFT + NEGF method can be successfully used to obtain the reasonable quantitative estimates of temperature dependent BGSs, optical absorption and PV properties of p–n heterojunctions.
High-pressure induces topology boosting thermoelectric performance of Bi2Te3
Authors: Cheng Jiaen , Wang Fei , Lian Min , Wang Dianzhen , Wang Lu , You Cun , Wang Xinglin , Ge Yufei , Liang Xiao , Tao Qiang , Chen Yanli , Zhu Pinwen 
Published: February 2024

Abstract
Decoupling conductivity

(
σ
)

and Seebeck coefficient

(
S
)

by electronic topological transitions (ETT) under high pressure (2–4 GPa) is a promising method for bismuth telluride (Bi2Te3) to optimize thermoelectric (TE) performance. However, the

S

cannot dramatically increase with increasing

σ

when ETT occurs in Bi2Te3, which impedes optimizing TE performance by utilizing ETT in Bi2Te3. A new strategy of enhanced ETT by combining lattice distortions and high pressure is proposed in this work. The lattice distortions in Bi2Te3 were introduced by high pressure and high temperature (HPHT) treatment to generate surplus dislocations. The in-situ measurements of

σ

and

S

at HPHT in Bi2Te3 with lattice distortions show an enhanced ETT effect at 2 GPa, which causes decouple

σ

and

S

with an anomalous increase in its

|
S
|

about 22%. The ETT effect causes the figure of merit (

Z
T

) of Bi2Te3 can be improved to 0.275 at 1.50–2.62 GPa, 460 K, it is more than 62% compared with 0.79 GPa, at 450 K. The excellent TE performance of Bi2Te3 arising from the lattice distortions can result in local non-hydrostatic pressure which enhances ETT under high pressure. This work provides a new strategy to enhance ETT to decouple

σ

and

S

, and search for better TE materials from the pressure dimension in the future.
Advanced spectroscopic investigation of colour centres in LiF crystals irradiated with monochromatic hard x-rays
Authors: Vincenti M A , Montereali R M , Bonfigli F , Nichelatti E , Nigro V , Piccinini M , Koenig M , Mabey P , Rigon G , Dabrowski H J , Benkadoum Y , Mercere P , Da Silva P , Pikuz T , Ozaki N , Makarov S , Pikuz S , Albertazzi B 
Published: February 2024

Abstract
Nominally-pure lithium fluoride (LiF) crystals were irradiated with monochromatic hard x-rays of energy 5, 7, 9 and 12 keV at the METROLOGIE beamline of the SOLEIL synchrotron facility, in order to understand the role of the selected x-ray energy on their visible photoluminescence (PL) response, which is used for high spatial resolution 2D x-ray imaging detectors characterized by a wide dynamic range. At the energies of 7 and 12 keV the irradiations were performed at five different doses corresponding to five uniformly irradiated areas, while at 5 and 9 keV only two irradiations at two different doses were carried out. The doses were planned in a range between 4 and 1.4 × 103 Gy (10.5 mJ cm−3 to 3.7 J cm−3), depending on the x-ray energy. After irradiation at the energies of 7 and 12 keV, the spectrally-integrated visible PL intensity of the F2 and F3
+ colour centres (CCs) generated in the LiF crystals, carefully measured by fluorescence microscopy under blue excitation, exhibits a linear dependence on the irradiation dose in the investigated dose range. This linear behaviour was confirmed by the optical absorption spectra of the irradiated spots, which shows a similar linear behaviour for both the F2 and F3
+ CCs, as derived from their overlapping absorption band at around 450 nm. At the highest x-ray energy, the average concentrations of the radiation-induced F, F2 and F3
+ CCs were also estimated. The volume distributions of F2 defects in the crystals irradiated with 5 and 9 keV x-rays were reconstructed in 3D by measuring their PL signal using a confocal laser scanning microscope operating in fluorescence mode. On-going investigations are focusing on the results obtained through this z-scanning technique to explore the potential impact of absorption effects at the excitation laser wavelength.
Twist angle, strain, corrugation and moire unit cell in twisted bi-layer graphene
Authors: Pal Veer , Ajay  
Published: February 2024

Abstract
Knowledge of the internal configuration of carbon atoms inside a moire unit cell of twisted bi-layer graphene (TBG) would enhance the accuracy of many-body quantum mechanical calculations related to TBG. This work put forward a comprehensive theoretical study of moire pattern in TBG, supported with computational analysis; which seek a mechanism to determine the internal configuration of carbon atoms inside a moire unit cell of TBG. This study first time establishes that all twist angles are commensurate twist angles which produce perfectly periodic commensurate moire patterns of TBG. It is also first time established that strain appearing in moire patterns of TBG can occur purely due to intrinsic reasons. Taking some insight from available experimental data related to TBG systems and conventional bi-layer graphene systems, a mathematical model is also presented for corrugation in TBG. Finally we present an universal algorithm to determine the internal configuration of carbon atoms inside a moire unit cell of TBG, which is first of its kind.