bluuebunny/crossref_metadata_2025_split huggingface dataset:
Buffalopox: An emerging cutaneous disease in humans
Authors: Burningham Kevin M. , Hinojosa Tiffany , Cavazos Annia , Goyal Tarang , Tyring Stephen K. 
Published: December 2023

AbstractBackgroundBuffalopox virus (BPXV) infection is an under‐recognized zoonotic disease associated with recently reported outbreaks in humans in South Asia. It is frequently isolated from skin lesions in cattle and buffalos, and can be transmitted to humans by direct contact with the skin of infected animals and fomites. Very little data exist to inform treatment guidelines.Case ReportWe present a case report of a 50‐year‐old male with this rare but emerging disease.ConclusionsAs outbreaks of viral skin disease such as buffalopox become more common, it is essential for dermatologists to be familiar with their cutaneous manifestations.
The association between atopic dermatitis and inflammatory bowel disease in adults: A cross‐sectional study in a specialized atopic dermatitis clinic
Authors: Rom H. , Snir Y. , Schwartz N. , Hodak E. , Leshem Y. A. 
Published: December 2023

AbstractBackgroundAtopic dermatitis (AD) and inflammatory bowel disease (IBD) share genetic susceptibility loci with immune regulation functions. Atopic dermatitis was associated with IBD mostly in database studies.ObjectiveTo assess whether AD is associated with an increased prevalence of IBD in a tertiary dermatology clinic.MethodsA retrospective cross‐sectional analysis using medical records of adults with verified AD followed up at an AD clinic, compared with age‐ and sex‐matched (1:2) controls from the general dermatology clinic in the same hospital.ResultsOverall, 9/364 (2.47%) of patients with AD had verified IBD, compared with 7/725 (0.97%) of controls (p = 0.0512). In multivariable logistic regression adjusting for age, gender and smoking, the association became significant (adjusted OR = 3.89, 95% CI: 1.28–11.85). Stratified for AD severity, only moderate‐to‐severe AD was associated with IBD (p = 0.035), with an adjusted OR of 4.45 (95% CI: 1.43–13.90). Mild AD was not associated with IBD, but the study was not powered for this sub‐analysis. In the AD group, older age was associated with IBD (p = 0.0172).ConclusionThis study, in a robustly verified cohort of patients, supports an association between AD, especially the moderate‐to‐severe forms, and IBD. A multidisciplinary approach for patients with moderate‐to‐severe AD should extend to consider IBD.
Short sellers and capital structure dynamics
Authors: Mishra Suchismita , Öztekin Özde , Rahman Anisur 
Published: December 2023

AbstractManagers tend to issue equity when a firm is overvalued. Short selling is more frequent among overvalued firms. By conditioning short selling on overvaluation, we show that short selling increases leverage, lenghtens debt maturity, and speeds up adjustment to target leverage. The leverage increase is more pronounced in firms with independent boards and an increased likelihood of misvaluation, is driven by overvaluation relative to long‐run value, and occurs through lower equity issuance and higher long‐term debt issuance. Analyses using the exogenous shock to the short‐selling environment from the US Securities and Exchange's Reg SHO pilot program suggest these results are causal.
Physical frailty and survival time after the onset of functional disability: Is there a sex difference?
Authors: Makino Keitaro , Raina Parminder , Griffith Lauren E. , Lee Sangyoon , Harada Kenji , Chiba Ippei , Katayama Osamu , Tomida Kouki , Morikawa Masanori , Makizako Hyuma , Shimada Hiroyuki 
Published: December 2023

AbstractBackgroundPhysical frailty accelerates the timing of both subsequent disability and death; however, evidence regarding the impact of frailty on the period from disability onset to death and sex differences of this impact is lacking. The aim of this study was to examine the relationship among physical frailty, disability, death, and sex differences.MethodsThis Japanese cohort study included 10,524 community‐dwelling people aged ≥65 years. Physical frailty was operationalized by key phenotypes as per Fried's criteria (slowness, weakness, exhaustion, weight loss, and low activity) at baseline. We calculated hazard ratios (HRs) with 95% confidence intervals (CIs) for disability onset and post‐disability survival according to the frailty status.ResultsDuring a 5‐year follow‐up, the risk of disability onset for pre‐frailty (HR: 1.74, 95% CI: 1.51–2.00) and frailty (HR: 3.27, 95% CI: 2.77–3.87) were significantly higher than that for robust people. Furthermore, among participants who developed disabilities within 5 years (n = 1481), the risk of post‐disability death for pre‐frailty was not different from that for robust (HR: 1.49, 95% CI: 0.99–2.24), but frailty showed a higher risk of post‐disability death than did robust people. (HR: 1.75, 95% CI: 1.13–2.72). In the sex‐stratified analysis, although the female group showed no association between frailty status and post‐disability death (HR: 1.21, 95% CI: 0.63–2.33 in pre‐frailty; HR: 1.24, 95% CI: 0.60–2.57 in frailty), the male group showed higher risk of post‐disability death in both pre‐frailty (HR: 1.74, 95% CI: 1.03–2.96) and frailty (HR: 2.32, 95% CI: 1.32–4.09).ConclusionsPhysical frailty shortens the period from disability onset to death. Additionally, the impact of frailty on post‐disability death is greater for males than for females. Our findings suggest that physical frailty is an important clinical indicator distinct from disability and that interventions to prevent and address frailty in men need further investigation.
Insufficient sleep blunts positive, but not negative, affective response to emotionally complex film clips
Authors: Minkel Jared , Pascuzzi Emma , Mushkat Zoe , Gentes Emily , Adams Sue K. 
Published: December 2023

SummaryThe effects of sleep deprivation on emotional function are not yet fully understood. Although sleep deprivation has been shown to have larger effects on positive emotional reactivity than on negative, this research has been limited by the use of separate stimuli for positive and negative emotion elicitation. Different sets of stimuli represent a confound that makes it difficult to interpret this difference with confidence. The study reported here was designed to overcome this limitation by using film clips that elicit both positive and negative emotional responses at the same time. Undergraduate participants (33 female, 2 male) completed a laboratory‐based emotion elicitation procedure using these film clips. Differences in sleep deprivation, estimated by subjective sleepiness and reaction times, were used to predict responses to these emotion probes. Greater subjective sleepiness was associated with significantly lesser positive responses to the film clips (rs = −0.37, p = 0.03). The relationship between subjective sleepiness and negative responses to the same clips was smaller and not significant (rs = −0.11, p = 0.51). Reaction times were not related to subjective emotional responses in this sample (all p > 0.40). These results support the theory that sleepiness has asymmetrical effects on positive and negative emotional functioning.
Diet in phenotypically divergent sympatric species of African weakly electric fish (genus: Campylomormyrus)—A hybrid capture/HTS metabarcoding approach
Authors: Amen Rahma , Havenstein Katja , Kirschbaum Frank , Tiedemann Ralph 
Published: December 2023

AbstractEcological speciation within the mormyrid genus Campylomormyrus resulted in sympatric species exhibiting divergence in their feeding apparatus and electric organ discharge (EOD). This study documents the overall diet of the genus Campylomormyrus and examines the hypothesis that the Campylomormyrus radiation is caused by adaptation to different food sources. We performed diet assessment of five sympatric Campylomormyrus species (C. alces, C. compressirostris, C. curvirostris, C. tshokwe, C. numenius) and their sister taxon Gnathonemus petersii with markedly different snout morphologies and EODs using hybrid capture/HTS DNA metabarcoding of their stomach contents. Our approach allowed for high taxonomic resolution of prey items, including benthic invertebrates, allochthonous invertebrates and vegetation. Comparisons of the diet compositions using quantitative measures and diet overlap indices revealed that all species are able to exploit multiple food niches in their habitats, that is fauna at the bottom, the water surface and the water column. A major part of the diet is larvae of aquatic insects, such as dipterans, coleopterans and trichopterans, known to occur in holes and interstitial spaces of the substrate. The results indicate that different snout morphologies and the associated divergence in the EOD could translate into different prey spectra. This suggests that the diversification in EOD and/or morphology of the feeding apparatus could be under functional adaptation.
Comparison of maxillary transversal changes between auxiliary beta‐titanium expansion arch and miniscrew‐assisted rapid palatal expansion
Authors: Sader Luis Henrique Braga , Siécola Gustavo , Marin Ramirez Cecilia Maria , Otazu Aldo , Torres Dino Marcelo , Cotrin Paula , Valarelli Fabrício Pinelli , Pinzan‐Vercelino Célia Regina Maio , Freitas Karina Maria Salvatore 
Published: December 2023

AbstractObjective(s)This study compared buccal bone thickness, dental inclinations and maxillary transverse width dimensions changes between auxiliary beta‐titanium expansion arch (AEA) and miniscrew‐assisted rapid palatal expansion (MARPE).Materials and MethodsThe sample consisted of 29 patients, aged between 18 and 40 years, with transverse maxillary deficiency and treated without extractions, divided into two groups: group AEA: comprised 13 individuals (initial mean age: 29.23 ± 9.13 years) treated using auxiliary beta‐titanium expansion arch; group MARPE: comprised 16 patients (initial mean age: 24.92 ± 7.60 years) treated with miniscrew‐assisted rapid palatal expansion. Buccal bone thickness, dental inclinations and transverse width dimensions (dental, nasal base and jugular) were measured in cone‐bean computed tomographies at pre‐ and post‐treatment stages. The variables were compared using the independent t‐test.ResultsThe buccal bone thickness was similar for both groups at the post‐treatment stage. The second premolars were significantly more buccal inclined in the AEA group and the right maxillary first molars in the MARPE group. The intercanine and intermolar distances were statistically significantly greater in the MARPE group. Changes in dental arch transverse dimensions were significantly greater for the MARPE group.ConclusionBoth treatment protocols corrected the maxillary transverse discrepancy; however, MARPE provided greater correction.
The misconception of soil organic carbon sequestration notion: When do we achieve climate benefit?
Authors: Petersson Tashina , Antoniella Gabriele , Chiriacò Maria Vincenza , Perugini Lucia , Chiti Tommaso 
Published: December 2023

AbstractSoil organic carbon (SOC) sequestration is a key function of natural and semi‐natural ecosystems. Restoring this property in terrestrial ecosystems has become central to the EU's climate change mitigation and adaptation strategies. However, SOC sequestration is a widely misunderstood concept. The different methodological approaches used to investigate and compare SOC stock under sustainable agricultural practices play a key role in reinforcing misconceptions about this complex process. This commentary paper aimed not only to provide a clear definition of SOC sequestration, but also to interpret the results that can be obtained for SOC stock change estimation using the SOC stock difference and the paired comparison methods, as well as to identify the soil carbon‐related processes that achieve climate mitigation. SOC sequestration can be defined as the progressive increase in a site's SOC stock compared with pre‐intervention via a net depletion and transfer of atmospheric CO2 into the soil, where it is retained as soil organic matter (SOM), by plants, plant residues, or other organic solids such as the material derived from the organic fraction of farming solid waste, which can be used as a fertilizer (e.g., manure, compost, biochar, and digestate), and that is produced or derived from that land unit. To date, the most appropriate way to determine whether a land unit's soil is a sink or rather a source of atmospheric CO2 is to implement the SOC stock difference method, provided the non‐occurrence of carbon exchange between ecosystems.
Arabidopsis BBX14 is involved in high light acclimation and seedling development
Authors: Atanasov Vasil , Schumacher Julia , Muiño Jose M. , Larasati Catharina , Wang Liangsheng , Kaufmann Kerstin , Leister Dario , Kleine Tatjana 
Published: December 2023

SUMMARYThe development of photosynthetically competent seedlings requires both light and retrograde biogenic signaling pathways. The transcription factor GLK1 functions at the interface between these pathways and receives input from the biogenic signal integrator GUN1. BBX14 was previously identified, together with GLK1, in a core module that mediates the response to high light (HL) levels and biogenic signals, which was studied by using inhibitors of chloroplast development. Our chromatin immunoprecipitation‐Seq experiments revealed that BBX14 is a direct target of GLK1, and RNA‐Seq analysis suggests that BBX14 may function as a regulator of the circadian clock. In addition, BBX14 plays a role in chlorophyll biosynthesis during early onset of light. Knockout of BBX14 results in a long hypocotyl phenotype dependent on a retrograde signal. Furthermore, the expression of BBX14 and BBX15 during biogenic signaling requires GUN1. Investigation of the role of BBX14 and BBX15 in GUN‐type biogenic (gun) signaling showed that the overexpression of BBX14 or BBX15 caused de‐repression of CA1 mRNA levels, when seedlings were grown on norflurazon. Notably, transcripts of the LHCB1.2 marker are not de‐repressed. Furthermore, BBX14 is required to acclimate plants to HL stress. We propose that BBX14 is an integrator of biogenic signals and that BBX14 is a nuclear target of retrograde signals downstream of the GUN1/GLK1 module. However, we do not classify BBX14 or BBX15 overexpressors as gun mutants based on a critical evaluation of our results and those reported in the literature. Finally, we discuss a classification system necessary for the declaration of new gun mutants.
The stochastic Schwarz lemma on Kähler manifolds by couplings and its applications
Authors: Chae Myeongju , Cho Gunhee , Gordina Maria , Yang Guang 
Published: December 2023

AbstractWe first provide a stochastic formula for the Carathéodory distance in terms of general Markovian couplings and prove a comparison result between the Carathéodory distance and the complete Kähler metric with a negative lower curvature bound using the Kendall–Cranston coupling. This probabilistic approach gives a version of the Schwarz lemma on complete noncompact Kähler manifolds with a further decomposition Ricci curvature into the orthogonal Ricci curvature and the holomorphic sectional curvature, which cannot be obtained by using Yau–Royden's Schwarz lemma. We also prove coupling estimates on quaternionic Kähler manifolds. As a by‐product, we obtain an improved gradient estimate of positive harmonic functions on Kähler manifolds and quaternionic Kähler manifolds under lower curvature bounds.
Interventions to prevent or manage workplace violence against student nurses during clinical placement: a systematic review protocol
Authors: Dafny Hila Ariela , McCloud Christine , Champion Stephanie , Pearson Vincent , Hines Sonia , Brown Shannon , Phillips Craig , Waheed Nasreena , Cabilan C.J. , Johnston Sandra 
Published: December 2023

Objectives:
The objective of this review is to investigate the effectiveness of workplace violence management or prevention interventions, including strategies, protocols, and policies, to address violence against, and provide support to, registered nursing students (RNS) following incidents of violence during clinical placement.

Introduction:
Workplace violence is a global issue that affects victims’ physical and mental health. RNS are especially vulnerable to workplace violence because of their limited work experience and confidence. These students often feel shocked and unprepared when experiencing workplace violence due to limited education and support provided by educational institutions or clinical sites. Workplace violence can lead to anxiety, decreased confidence, and professional attrition. There is a need to systematically synthesize the evidence on workplace violence management and prevention to support nursing students during clinical placement.

Inclusion criteria:
The review will consider studies assessing the effectiveness of interventions to address workplace violence or improve support for RNS. Studies that report on educational interventions or pre-clinical placement strategies and measure the preparedness of students will also be considered. Study designs will be limited to quantitative methods that evaluate intervention effectiveness.

Methods:
Databases to be searched include MEDLINE (Ovid), CINAHL (EBSCOhost), Web of Science Core Collection, Scopus, Embase (Ovid), Cochrane Central, ERIC (ProQuest), ProQuest Central, ProQuest Social Science Premium Collection, and ProQuest Dissertations and Theses Global. Two independent reviewers will screen, review, appraise, and extract data from eligible articles. For data synthesis, studies will be pooled using JBI SUMARI. The GRADE approach for grading the certainty of evidence will be followed and a Summary of Findings will be created.

Review registration:
PROSPERO CRD42022377318
Pharmacy practice and First Peoples health equity: a scoping review protocol
Authors: Rothwell Michelle , Carlisle Karen , Cairns Alice , Wallace Valda , McDermott Karl , Topp Stephanie 
Published: December 2023

Objective:
The objective of this review is to examine and describe global pharmacy practice strategies and interventions designed to achieve health equity for First Peoples.

Introduction:
Access to medicines and quality use of medicines is critical to achieving health equity for First Peoples. Pharmacists are uniquely placed to lead the charge in transforming current health systems, reducing health disparities, and bolstering the movement toward health equity.

Inclusion criteria:
Global studies describing pharmacy practice strategies and interventions designed to achieve health equity for First Peoples will be considered for inclusion in the review. Studies relating to all areas of pharmacy practice, including community and clinical pharmacy, social, administrative, pharmaceutical sciences, practice, teaching, research, advocacy, or service relevant to the review’s objective will also be considered for inclusion. The types of studies to be included are qualitative, quantitative, and mixed methods systematic reviews, scoping reviews, literature reviews, and gray literature.

Methods:
This review will be conducted in accordance with JBI methodology for scoping reviews. Embase, MEDLINE, Scopus, CINAHL, and gray literature sources will be searched from 1998 to the present. Titles, abstracts, and full texts will be screened against the inclusion criteria. Strategies and interventions identified in the included reviews will be mapped to a published framework, outlining actionable strategies for pharmacy practice inclusion in sustainable efforts to achieve health equity. Qualitative content analysis and descriptive statistics will be utilized with data presented in tables, accompanied by a narrative.

Review registration:
Open Science Framework osf.io/qa64b
Insights into pathophysiology and therapeutic strategies for heat stroke: Lessons from a baboon model
Authors: Abdullah Mashan , Ehaideb Salleh , Roberts George , Bouchama Abderrezak 
Published: December 2023

AbstractHeat stroke is a perilous condition marked by severe hyperthermia and extensive multiorgan dysfunction, posing a considerable risk of mortality if not promptly identified and treated. Furthermore, the complex biological mechanisms underlying heat stroke‐induced tissue and cell damage across organ systems remain incompletely understood. This knowledge gap has hindered the advancement of effective preventive and therapeutic strategies against this condition. In this narrative review, we synthesize key insights gained over a decade using a translational baboon model of heat stroke. By replicating heat stroke pathology in a non‐human primate species that closely resembles humans, we have unveiled novel insights into the pathways of organ injury and cell death elicited by this condition. Here, we contextualize and integrate the lessons learned concerning heat stroke pathophysiology and recovery, areas that are inherently challenging to investigate directly in human subjects. We suggest novel research directions to advance the understanding of the complex mechanisms underlying cell death and organ injury. This may lead to precise therapeutic strategies that benefit individuals suffering from this debilitating condition.
Draft genome sequence of
Amycolatopsis camponoti
RTGN1, a bacterial endophyte isolated from
Alnus glutinosa
root nodules
Authors: Thompson Ryan Michael , Fox Edward M. , Montero-Calasanz Maria del Carmen 
Published: December 2023

ABSTRACT

Here, we report the draft genome sequence of
Amycolatopsis
camponoti RTGN1, a bacterial endophyte of
Alnus glutinosa
root nodules, collected from Saltwell Park, United Kingdom. The genome is 11.9 Mbp in size, composed of 147 contigs, with an N
50
of 179,211 bp and presenting a GC content of 70.9%.
Metagenomes and metagenome-assembled genomes from a sequentially fed anaerobic digester treating solid organic municipal waste
Authors: Nesbø Camilla L. , Fitamo Temesgen M. , Lee Hyunwoo , Edwards Elizabeth A. 
Published: December 2023

ABSTRACT
We present a data set of four metagenomes and 281 metagenome-assembled genomes describing the microbial community of a laboratory-scale high solids anaerobic digester. Our objective was to obtain information on the coding potential of the microbial community and draft genomes of the most abundant organisms in the digester.