bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research on the mechanism of the two-dimensional ultrasonic surface burnishing process to enhance the wear resistance for aluminum alloy
Authors: Zhou Zhen-Yu , Zheng Qiu-Yang , Li Yu , Ding Cong , Peng Guang-Jian , Piao Zhong-Yu 
Published: December 2023

AbstractThe gradient nanostructure is machined on the aluminum (Al) alloy by the two-dimensional ultrasonic surface burnishing process (2D-USBP). The mechanism of why the gradient nanostructure enhances wear resistance is investigated. The mechanical properties and microstructure characterization for the gradient nanostructure are performed by operating a nanoindenter, transmission electron microscopy (TEM), and electron backscattered diffraction (EBSD). Dry wear tests are performed on the samples before and after machining to evaluate the wear resistance and mechanisms. The effect of the gradient nanostructure on the wear resistance is explored by developing the crystal plasticity (CP) finite element and molecular dynamics (MD) models. The characterization results show that the 2D-USBP sample prepared a gradient structure of ∼600 µm thick on the aluminum surface, increasing the surface hardness from 1.13 to 1.71 GPa and reducing the elastic modulus from 78.84 to 70.14 GPa. The optimization of the surface microstructure and the increase of the mechanical properties effectively enhance the wear resistance of the sample, with 41.20%, 39.07%, and 54.58% of the wear scar areas for the 2D-USBP treated samples to the original samples under 5, 10, and 15 N loads, respectively. The gradient nanostructure hinders the slip of dislocations inside the sample during the wear process and reduces the size and scope of plastic deformation; meanwhile, the resistance to deformation, adhesion, and crack initiation and propagation of the sample surface is improved, resulting in enhanced wear resistance.
Railway Safety Assessment Model Solving by Decision Tree and PSO Algorithm
Authors: Jun Liu , Wanqi Wang , Ping Li , Xiaoning Ma , Yanhua Wu , Wenya Xu 
Published: December 2023

AbstractSafety assessment and safety warning in intelligent railway play an important role in safety management. This paper utilizes the PSO algorithm with bounds and time-varying attractor to obtain some parameters in the safety assessment model. Firstly, the safety assessment model is provided to evaluate the safety status on the existing problem, railway equipment and railway worker. Secondly, one objective function and three constraint conditions on training the safety assessment model are introduced to minimize the square error between the output and the safety classification level. Thirdly, it is important to discuss the convergence behavior and spectral radius on transfer matrix in the PSO algorithm with bounds and time-varying attractor. Finally, in order to show and demonstrate the effectiveness of the PSO algorithm, it is important to analyze the objective fitness, the swarm velocity, the time-varying attractor, the parameters in the safety assessment model and the computational time during the evolutionary process. And the PSO algorithm with bounds and time-varying attractor can solve parameter optimization problem on the railway safety assessment and warning.
Reactive Power Output Modeling of Synchronous Condenser in UHVDC Converter Station Based on Interlaced Superposition CNN-BiLSTM
Authors: Wang Lin , Wang Honghua , Lu Tianhang , Wang Chengliang 
Published: December 2023

AbstractTo guarantee stable power system operation, a synchronous condenser (SC) is configured in an ultra-high voltage direct current (UHVDC) converter station to provide dynamic reactive power support to the power system. The research on the reactive power output modelling of a SC in an UHVDC converter station has important theoretical significance and practical value for the reactive power control of a SC in an UHVDC converter station. Focusing on the reactive power regulation system of the SC with strong coupling, multivariable, and nonlinear features, it is difficult for the universal analytic method to build the SC reactive power output model. A novel reactive power output model of the SC in the UHVDC converter station based on interlaced superposition convolutional neural network-bidirectional long short-term memory (CNN-BiLSTM) is proposed, in which a novel interlaced superposition CNN composed of convolution units with two different structures is built to increase the depth of the network and avoid over-fitting. Particularly the branch channels of convolution units with two different structures are connected by a convolution layer and a skip connection respectively. The interlaced superposition CNN-BiLSTM model is that the combination of the interlaced superposition CNN model and BiLSTM model for improving the model accuracy and generic capability. The Bayesian optimization method is used to optimize its hyperparameters. The application of interlaced Superposition CNN-BiLSTM in SC reactive power output modelling is a new technology. The excitation voltage and excitation current of the SC are used as inputs for the training and testing sampled data, and the reactive power of the SC is used as outputs for the training and testing sampled data. Therefore, the reactive power output model of a SC in an UHVDC converter station based on interlaced superposition CNN-BiLSTM is obtained, and it attains a low root mean square error (RMSE = 0.126750) and a high determination coefficient (R2 = 0.999999).
An RBF-FD Method for Numerical Solutions of 2D Diffusion-Wave and Diffusion Equations of Distributed Fractional Order
Authors: Taghipour Fatemeh , Shirzadi Ahmad , Safarpoor Mansour 
Published: December 2023

AbstractThe subject of this paper is to propose a numerical algorithm for solving 2D diffusion and diffusion-wave equations of distributed order fractional derivatives. Such equations arise in modelling complex systems and have many important applications. Existence of integral term over the order of fractional derivative causes the high complexity of these equations and so their numerical solutions needs special cares. Using Gauss quadrature approach for discretizing the integral term of fractional derivative converts the distributed equation into a multi-term fractional differential equation. Then, the time variable is discretized with a suitable finite difference approach. The resultant semi-discretized equations are fully discretized by a radial basis function-generated finite difference based method. Convergence of the method are studied numerically. Various kind of test problems are considered for a comprehensive numerical study and the results confirm the efficiency of the method.
Properties of flyash based wood geopolymer composite
Authors: Mamatha B. S. , Sujatha D. , Uday D. N. , Kiran M. C. 
Published: December 2023

AbstractGeopolymers are inorganic adhesive synthesized from industrial waste such as fly ash thus the development of wood geopolymer composite would be a low carbon footprint material. Geopolymers, being a non-formaldehyde adhesive can be used as an alternative binder for wood based composites where environmentally friendly and sustainability of product is important. In this study flyash as precursor is been used in the development of wood geopolymer composite product. Flyash is activated with a combination of sodium hydroxide and sodium silicate solutions at a weight ratio of 1:2.5 for geopolymer formation. The study investigated the properties of wood geopolymer composite made with ratios of wood particle to flyash percentage (23/77), (37/62), (44/55), (50/50) and (57/43). Geopolymer formation was observed by X-ray Diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR). Influence of wood particles in wood geopolymer composite were observed by Scanning electron microscope. The study shows that the water absorption and thickness selling properties of all the formulations of wood geopolymer composites are comparable with the medium density particle board and cement-bonded particleboard according to the IS:3087–2005 standard and IS: 12406: respectively. Highest mechanical properties and good bond strength was obtained by the composite containing 23% wood particle ratio with 77% percent flyash. However, still improvement in mechanical properties is needed to achieve the mechanical properties comparable to cement bonded particle board.
Association of vancomycin-induced acute kidney injury with trough versus AUC monitoring in patients receiving extended durations of therapy
Authors: Tyler Pitcock C. , Schadler Aric , Burgess David S. , Burgess Donna R. , Cotner Sarah E. , Van Hoose Jeremy , Gregory Eric R. , Wallace Katie L. 
Published: December 2023

Abstract

Objective:
Vancomycin therapy is associated with an increased risk of acute kidney injury (AKI). Previous studies suggest that area under the curve (AUC) monitoring reduces the risk of AKI, but literature is lacking to support this in patients receiving longer durations of vancomycin therapy.

Design:
Retrospective cohort study.

Method:
Patients ≥18 years old, admitted between August 2015 and July 2017 or October 2017 and September 2019, and received at least 14 days of intravenous (IV) vancomycin therapy were included in the study. Our primary outcome was the incidence of AKI between trough monitoring and AUC monitoring groups using Kidney Disease Improving Global Outcomes criteria. Secondary outcomes included inpatient mortality, median inpatient length of stay, and median intensive care unit length of stay.

Results:
Overall, 582 patients were included in the study, with 318 patients included in the trough monitoring group and 264 included in the AUC monitoring group. The median duration of vancomycin therapy was 23 days (interquartile range, 16–39). Patients within the trough monitoring group had a higher incidence of AKI compared to the AUC monitoring group (45.6% vs 28.4%, p < 0.001). Furthermore, logistic regression analysis showed that AUC monitoring was associated with a 54% lower incidence of AKI (OR 0.46, 95% CI [0.31–0.69]). All-cause inpatient mortality was numerically higher in the trough monitoring group (12.9% vs 8.3%, p = 0.078).

Conclusions:
In patients who received at least 14 days of IV vancomycin therapy, AUC monitoring was associated with a lower incidence of AKI.
Contesting the Lonely Queen
Authors: Hanna Monica 
Published: December 2023

AbstractThe bust of Nefertiti symbolizes the transformation of the Egyptian heritage where the West has become the rightful heir of Ancient Egypt through a system of knowledge production that controls the Egyptian cultural heritage in Western Museum collections. This article explores the intricacies of the entanglement of cultural property with heritage politics projected on the famous bust. It is the best example to discuss decolonization and its ethical implications on museum practice in the twenty-first century and Egyptology as an area study. The article discusses the legal and ethical framework of the bust of Nefertiti’s discovery, export, and current exhibition and its complex receptions in Germany and Egypt.
Analysis of a SARIMA-XGBoost model for hand, foot, and mouth disease in Xinjiang, China
Authors: Man Haojie , Huang Hanting , Qin Zhuangyan , Li Zhiming 
Published: December 2023

Abstract
Hand, foot, and mouth disease (HFMD) is a common childhood infectious disease. The incidence of HFMD has a pronounced seasonal tendency and is closely related to meteorological factors such as temperature, rainfall, and wind speed. In this paper, we propose a combined SARIMA-XGBoost model to improve the prediction accuracy of HFMD in 15 regions of Xinjiang, China. The SARIMA model is used for seasonal trends, and the XGBoost algorithm is applied for the nonlinear effects of meteorological factors. The geographical and temporal weighted regression model is designed to analyze the influence of meteorological factors from temporal and spatial perspectives. The analysis results show that the HFMD exhibits seasonal characteristics, peaking from May to August each year, and the HFMD incidence has significant spatial heterogeneity. The meteorological factors affecting the spread of HFMD vary among regions. Temperature and daylight significantly impact the transmission of the disease in most areas. Based on the verification experiment of forecasting, the proposed SARIMA-XGBoost model is superior to other models in accuracy, especially in regions with a high incidence of HFMD.
Contextual dilution in French gender inclusive writing: An experimental investigation
Authors: Pozniak Céline , Corbeau Emma , Burnett Heather 
Published: December 2023

AbstractGender inclusive writing, a term that refers to a wide range of feminist linguistic practices aimed at reducing linguistic androcentrism, has been the topic of heated debates in France. Recent experimental studies have investigated its interpretation and showed that inclusive forms with the point médian (“étudiant·e·s”) and repetition (“étudiants et étudiantes”) feminize participants’ mental representations compared to the generic masculine (“étudiants”). In this article, we bring novel results from three experiments investigating the interpretation of these two inclusive forms in a more detailed context (university brochures). We find that the point médian is subject to “context dilution” effects: its meaning disappears in rich contexts, while repetition consistently changes readers’ mental representations, provided it is used systematically. We argue that our results show the necessity of looking at more ecological contexts in experimental (socio)linguistics for understanding the interpretation and processing of socially important linguistic variants.
The Poona Pact, Indian National Congress and the descriptive and substantive representation of Dalits in colonial India
Authors: Biswas Sujay 
Published: December 2023

AbstractWithin the prevailing historiographical tradition of modern India, critics see the Poona Pact as having “disenfranchised” Dalits, which they attribute to the fact that, due to the numerical superiority of caste Hindus, the implementation of joint electorates resulted in the consolidation of power within the Indian National Congress: the party that, critics allege, protected the interests of the caste Hindu community. Critics further argue that Dalit candidates who successfully ran for office under the Congress party’s banner, garnering support mostly from caste Hindu voters, failed to speak for the interests of the Dalit community effectively. This article examines the returns of the provincial assembly elections held in 1936–1937 and 1945–1946, as well as the functioning of the Congress ministries in the provinces of British India between 1937 and 1939 and 1946 and 1947 to challenge the criticisms mentioned above and to argue that the inclusion of reserved seats, primary elections, and cumulative voting mechanisms had a significant role in enhancing the potential of the Poona Pact to ensure genuine descriptive representation of Dalits. The article also finds that the affiliation of Dalit legislators with the Congress party had a beneficial impact on their substantive representation in the provincial legislatures where the Congress formed ministries because Dalit interests and the ideological and programmatic dynamics of the Congress party were congruent. In this context, Gandhi, a member of the caste Hindu community, played the role of a “critical actor” who encouraged the Congress party to undertake measures to advance the interests of the Dalit community. Moreover, a powerful and autonomous anti-untouchability movement led by the Harijan Sevak Sangh played a crucial role in enhancing the institutional capabilities of the Congress governments, enabling them to effectively address the concerns and challenges faced by the Dalit community, which further bolstered the substantive representation of Dalits.
Strongly Nonlinear Effects on Determining Internal Solitary Wave Parameters From Surface Signatures With Potential for Remote Sensing Applications
Authors: Xu Tao , Chen Xu , Li Qun , He Xiao , Wang Jing , Meng Jing 
Published: December 2023

AbstractThe inversion of remote sensing signatures of internal solitary waves (ISWs) can retrieve dynamic characteristics in the ocean interior. However, the presence of ubiquitous large‐amplitude ISWs poses challenges to the commonly used weakly nonlinear methods for parameter retrieval. Through laboratory experiments, we establish a relationship between surface features and internal characteristics of ISWs by the remote sensing imaging mechanism. The results demonstrate that strong nonlinearity significantly influences the retrieval of ISWs, primarily manifested in the calculation of wave‐induced velocities and the applicability of ISW solutions. A fully nonlinear model Dubreil–Jacotin–Long equation is used in the retrieval and has been tested under different conditions. Mooring observations indicate that the determination of ISW parameters from satellite images is affected by the complexity of in situ stratification, but additional remote sensing information such as surface velocities enables us to perform retrievals even if the real‐time measurement of pycnocline depth is not available.
Activation of prefrontal parvalbumin interneurons ameliorates working memory deficit even under clinically comparable antipsychotic treatment in a mouse model of schizophrenia
Authors: Arime Yosefu , Saitoh Yoshito , Ishikawa Mikiko , Kamiyoshihara Chikako , Uchida Yasuo , Fujii Kazuki , Takao Keizo , Akiyama Kazufumi , Ohkawa Noriaki 
Published: December 2023

AbstractOne of the critical unmet medical needs in schizophrenia is the treatment for cognitive deficits. However, the neural circuit mechanisms of them remain unresolved. Previous studies utilizing animal models of schizophrenia did not consider the fact that patients with schizophrenia generally cannot discontinue antipsychotic medication due to the high risk of relapse. Here, we used multi-dimensional approaches, including histological analysis of the prelimbic cortex (PL), LC-MS/MS-based in vivo dopamine D2 receptor occupancy analysis for antipsychotics, in vivo calcium imaging, and behavioral analyses of mice using chemogenetics to investigate neural mechanisms and potential therapeutic strategies for working memory deficit in a chronic phencyclidine (PCP) mouse model of schizophrenia. Chronic PCP administration led to alterations in excitatory and inhibitory synapses, specifically in dendritic spines of pyramidal neurons, vesicular glutamate transporter 1 (VGLUT1) positive terminals, and parvalbumin (PV) positive GABAergic interneurons located in layer 2–3 of the PL. Continuous administration of olanzapine, which achieved a sustained therapeutic window of dopamine D2 receptor occupancy (60–80%) in the striatum, did not ameliorate these synaptic abnormalities and working memory deficit in the chronic PCP-treated mice. We demonstrated that chemogenetic activation of PV neurons in the PL, as confirmed by in vivo calcium imaging, ameliorated working memory deficit in this model even under clinically comparable olanzapine treatment which by itself inhibited only PCP-induced psychomotor hyperactivity. Our study suggests that targeting prefrontal PV neurons could be a promising therapeutic intervention for cognitive deficits in schizophrenia in combination with antipsychotic medication.
Characterisation of FLT3 alterations in childhood acute lymphoblastic leukaemia
Authors: Gutierrez-Camino Angela , Richer Chantal , Ouimet Manon , Fuchs Claire , Langlois Sylvie , Khater Fida , Caron Maxime , Beaulieu Patrick , St-Onge Pascal , Bataille Alain R. , Sinnett Daniel 
Published: December 2023

Abstract
Background
Alterations of FLT3 are among the most common driver events in acute leukaemia with important clinical implications, since it allows patient classification into prognostic groups and the possibility of personalising therapy thanks to the availability of FLT3 inhibitors. Most of the knowledge on FLT3 implications comes from the study of acute myeloid leukaemia and so far, few studies have been performed in other leukaemias.

Methods
A comprehensive genomic (DNA-seq in 267 patients) and transcriptomic (RNA-seq in 160 patients) analysis of FLT3 in 342 childhood acute lymphoblastic leukaemia (ALL) patients was performed. Mutations were functionally characterised by in vitro experiments.

Results
Point mutations (PM) and internal tandem duplications (ITD) were detected in 4.3% and 2.7% of the patients, respectively. A new activating mutation of the TKD, G846D, conferred oncogenic properties and sorafenib resistance. Moreover, a novel alteration involving the circularisation of read-through transcripts (rt-circRNAs) was observed in 10% of the cases. Patients presenting FLT3 alterations exhibited higher levels of the receptor. In addition, patients with ZNF384- and MLL/KMT2A-rearranged ALL, as well as hyperdiploid subtype, overexpressed FLT3.

Discussion
Our results suggest that specific ALL subgroups may also benefit from a deeper understanding of the biology of FLT3 alterations and their clinical implications.
Identification of PCPE-2 as the endogenous specific inhibitor of human BMP-1/tolloid-like proteinases
Authors: Vadon-Le Goff Sandrine , Tessier Agnès , Napoli Manon , Dieryckx Cindy , Bauer Julien , Dussoyer Mélissa , Lagoutte Priscillia , Peyronnel Célian , Essayan Lucie , Kleiser Svenja , Tueni Nicole , Bettler Emmanuel , Mariano Natacha , Errazuriz-Cerda Elisabeth , Fruchart Gaillard Carole , Ruggiero Florence , Becker-Pauly Christoph , Allain Jean-Marc , Bruckner-Tuderman Leena , Nyström Alexander , Moali Catherine 
Published: December 2023

AbstractBMP-1/tolloid-like proteinases (BTPs) are major players in tissue morphogenesis, growth and repair. They act by promoting the deposition of structural extracellular matrix proteins and by controlling the activity of matricellular proteins and TGF-β superfamily growth factors. They have also been implicated in several pathological conditions such as fibrosis, cancer, metabolic disorders and bone diseases. Despite this broad range of pathophysiological functions, the putative existence of a specific endogenous inhibitor capable of controlling their activities could never be confirmed. Here, we show that procollagen C-proteinase enhancer-2 (PCPE-2), a protein previously reported to bind fibrillar collagens and to promote their BTP-dependent maturation, is primarily a potent and specific inhibitor of BTPs which can counteract their proteolytic activities through direct binding. PCPE-2 therefore differs from the cognate PCPE-1 protein and extends the possibilities to fine-tune BTP activities, both in physiological conditions and in therapeutic settings.
Catalyst control over pentavalent stereocentres
Authors: Budeev Anton , Dong Jianyang , Häussinger Daniel , Sparr Christof 
Published: December 2023

AbstractA monumental diversity of catalytic methods imparts the ability to select one of two configurations of tetravalent stereocentres. Conversely, catalyst control over pentavalent stereocentres, where a fifth moiety bound to the central atom encodes an expanded stereochemical space, remained a challenge to be accomplished. Herein, we report the feasibility of the catalytic tractability of pentavalent stereocentres. A bifunctional iminophosphorane thiourea catalyst enables enantio- and diastereocontrol over pentavalent phosphoranes to differentiate configurationally stable enantiomers and ensembles of diastereomers which emerge together from a single stereocentre. The desired dioxophosphorane stereoisomers are obtained with excellent yield and selectivity (up to 99% yield, 96:4 e.r. and 99:1 d.r.), while stereodivergent catalysis reroutes the reaction for selective access to each of the viable stereoisomeric states of pentavalent phosphoranes. Considering the diversity of high-valent main group species, it is expected that catalyst control over pentavalent stereocentres significantly increases the synthetically addressable stereochemical space.