bluuebunny/crossref_metadata_2025_split huggingface dataset:
КОНСТРУКТ «ЗНАЧИМОГО ДРУГОГО» В МОЛОДЕЖНОМ СЕГМЕНТЕ СОВРЕМЕННОГО РОССИЙСКОГО ОБЩЕСТВА
Authors: Капанян Нина Николаевна 
Published: November 2023

Целью исследования является социокультурный анализ конструирования образа «значимого другого» в условиях, когда полистилизм современной культуры совпал с цифровизацией культурного пространства, макдонализацией производства массовой культуры, что оказывает существенное влияние на конструирование «значимого другого», особенно в молодежном сегменте российского общества.
Методологическую базу исследования составляют концептуальные подходы теории социализации, теории символического интеракционизма и теории социального конструирования реальности, теория «значимого другого» в интерпретации Дж. Мида, а также концептуальные идеи российских ученых о полистилистизме современной культуры, об особенностях цифровой социализации современной молодежи.
Результаты исследования. Социокультурный анализ конструирования «значимого другого» в молодежном сегменте современного российского общества показал, что существующая социальная неопределенность, рискогенность современного общества, продолжающаяся геополитическая нестабильность способствуют поиску «значимого другого», его актуальности для молодежи как образца для выбора собственной модели поведения.
Перспективу исследования составляет дальнейший социокультурный анализ конструирования образа «значимого другого» с акцентом на геополитическую напряженность и проведение специальной военной операции
Study the Applicability of a Shelf-Type Fish Drying Machine with a Heat Source from Coconut Shell Biomass
Authors: Budi Agus Sulistiyo , Bakhri Mohammad Samsul , Nurasri Yuli , Suripto Aghna Ilma Nurdin , Amir Sultan Krisna , Rojikin Rojikin 
Published: November 2023

The sun’s heat is usually utilized to dry traditional processed salted fish. However, its quality suffers as a result of the lengthy drying process. This issue can only be resolved with the help of efficient drying equipment. Advantages of artificial drying include selecting the drying capacity according to requirements, without requiring a considerable space, and managing the drying conditions. This research aims to discover an effective way to utilize biomass waste from coconut shells to speed up the drying process for salted fish. The study method involved several steps: acquiring data, analyzing the tools and machine, observing the machine, and designing a new machine. The three airspeed parameters tested in this study were 7 m/s, 10 m/s, and 12 m/s. The drying shelf reached a maximum temperature of 81.4 °C at 7 m/s, 100.3 °C at 10 m/s, and 99.4 °C at 12 m/s.
A rare case of myasthenia gravis in pregnancy with impending eclampsia
Authors: Singh Eshita , Hedge Radhesh 
Published: November 2023

Managing myasthenia gravis during pregnancy is challenging due to its high-risk nature, particularly among women aged 20 to 30, coinciding with childbearing age. This risk is exacerbated when myasthenia gravis coexists with pregnancy-induced hypertension, leading to an increased threat of morbidity and mortality for both the mother and the fetus.This case report highlights the challenges associated with simultaneous occurrence of myasthenia gravis and pregnancy-induced hypertension, leading to impending eclampsia. Employing a multidisciplinary approach involving obstetricians, neurologists, anesthesiologists, and neonatologists was pivotal in addressing the complexities presented. An emergency cesarean section at the eighth month addressed worsening pre-eclampsia and respiratory distress. Strategic administration of a bolus of steroids and pyridostigmine, coupled with the use of cardiac-stable ropivacaine for spinal anesthesia, contributed to a successful procedure. Post-delivery, neonatal observation confirmed the absence of transient myasthenia gravis, with subsequent normal follow-up examinations for both mother and baby. This case underscores the need for a comprehensive approach in managing these uncommon but high-risk conditions during pregnancy.
Presentación
Authors: Zorrilla de San Martín Verónica 
Published: November 2023

Esta edición de Cuadernos de Investigación Educativa está dedicada a la memoria de la académica argentina Inés Aguerrondo, docente de la Universidad ORT Uruguay e integrante del Comité Científico de la revista. Desde el Instituto de Educación lamentamos profundamente por su fallecimiento. Siempre será recordada por su profesionalismo, generosidad y capacidad de pensar una nueva escuela.
Es así que presentamos el volumen 14 número 2 de la revista, correspondiente al período comprendido entre julio y diciembre de 2023. El nuevo número reúne una selección de artículos de Argentina, Chile, Colombia, España, México, Perú y Uruguay, que abordan temas cruciales y de vanguardia en el ámbito educativo.
Los trabajos incluidos en esta ocasión reflejan la diversidad de enfoques y perspectivas que caracterizan a la investigación educativa iberoamericana, al ofrecer rigurosos análisis e innovadoras propuestas para la reflexión en el campo de la educación.
Postsurgical Pyoderma Gangrenosum After Minimally Invasive Transforaminal Lumbar Interbody Fusion
Authors: Varas-Rodríguez Emil , Cedeño Francis , Gonzalez-Diaz Gabriel , Vivas Joshua , Salgueiro Ariana , Dávila Katherine , Nevarez Pomales Oscar , Duyos Oscar 
Published: November 2023

Case:
A 61-year-old woman with lower back and radicular leg pain underwent minimally invasive spinal fusion at L5-S1. By postoperative day 6, she exhibited erythema, wound dehiscence, and necrotic changes. Although a necrotizing infection was initially suspected, multiple debridements and antibiotic therapy failed to improve her condition. The patient was eventually diagnosed with pyoderma gangrenosum (PG) and was managed with immunosuppressants and extended wound care.

Conclusion:
PG is a rare dermatosis that is often misdiagnosed, leading to inappropriate treatment, debridements, and additional complications. Prompt identification and multidisciplinary collaboration are key to preventing unnecessary interventions and achieving the best outcomes.
Delirium current practice among Intensive Care Units Doctors, Khartoum
Authors: El-Raheem Ghada Omer Hamad Abd , Hamid Sheema Hamid Seidna , Abdallah Mudawi Mohammed Ahmed 
Published: November 2023

Abstract
Delirium is a brain dysfunction that is characterized by attention and cognition disturbances in a fluctuating pattern. International guidelines recommend daily screening of delirium. The Confusion Assessment Method for the Intensive Care Unit (CAM-ICU) and the Intensive Care Delirium Screening Checklist (ICDSC) were the most commonly used for delirium assessment. The reasons why this study was developed were to identify the barriers and gaps in knowledge and practice. Multi-center Hospital-based Cross-Sectional study was developed. Multistage sampling technique was used. 72 ICU doctors were randomly selected. Statistical analysis was performed through chi-square test to determine association among variables. It was considered significant when p ≤ 0.05. More than 70% of doctors were ≤ 30 years and females. 69.4% had < 1year experience. 94.4% worked in medical ICUs. Less than 20% of the doctors used delirium assessment tools with a statistically significant difference based on experience (p=0.012). 13.9% had not assessed delirium regularly. Non-pharmacological management was applied by 76.4% of the doctors, communication with patients was the most frequent (75%). Haloperidol was the most used agent (83.3%). 40.3% of doctors had not stopped delirium medications on ICU discharge. Regular assessment of delirium was applied. Yet, the use of validated assessment tools was not common. Non-pharmacological management of delirium is important which is mostly done. Our doctors prescribed anti-psychotics for treatment of both forms of delirium and almost half of them did not stop medications on ICU discharge. Medication reconciliation and contact with the next in-charge of patients is important.
The Impact of Oil Refinery Exposure on Lung Cancer in Homs, Syria: A Retrospective Cohort Study
Authors: Daas Mahmoud , Bakir Hesham , ALShawaf Ahmad Zahi 
Published: November 2023

Abstract
As the global burden of lung cancer continues to increase, we cannot ignore the impact of environmental factors on its incidence. This retrospective cohort study aimed to shed light on the impact of an oil refinery on lung cancer incidence in the city of Homs, Syria, and to highlight the need for further research in this area. The investigation contrasted the occurrence of lung cancer in Homs, where an oil refinery has been a reason for anxiety because of the release of toxic gases, and Hama, the nearby city with no such air pollution. The results showed a higher incidence of lung cancer in Homs, with a relative risk of 2.21, suggesting a potential association between exposure to refinery gases and lung cancer. Lung cancer rates were higher among males than females in both cities, according to the study. This study underscores the importance of environmental monitoring and public health measures to mitigate the impact of air pollution on human health.
Mapping the Pandemic: A Review of GIS-based Spatial Modeling of COVID-19
Authors: Aboalyem Mustafa Shebani , Ismail Mohd Tahir 
Published: November 2023

Abstract
According to the World Health Organization (WHO), COVID-19 has caused more than 6.5 million deaths, while over 600 million people are infected. With regard to the tools and techniques of disease analysis, spatial analysis is increasingly being used to analyze the impact of COVID-19. The present review offers an assessment of research that used regional data systems to study the COVID-19 epidemic published between 2020 and 2022. The research focuses on: categories of the area, authors, methods, and procedures used by the authors and the results of their findings. This input will enable the contrast of different spatial models used for regional data systems with COVID-19. Our outcomes showed increased use of geographically weighted regression and Moran I spatial statistical tools applied to better spatial and time-based gauges. We have also found an increase in the use of local models compared to other spatial statistics models/methods.
Population-based Evidence for the Use of Serum Neurofilaments as Individual Diagnostic and Prognostic Biomarkers in Amyotrophic Lateral Sclerosis
Authors: Witzel Simon , Huss André , Nagel Gabriele , Rosenbohm Angela , Rothenbacher Dietrich , Peter Raphael , Baezner Hansjörg , Boertlein Axel , Dempewolf Silke , Schabet Martin , Hecht Martin , Kohler Andreas , Opherk Christian , Naegele Andrea , Sommer Norbert , Lindner Alfred , Alexudis Christoforos , Bachhuber Franziska , Halbgebauer Steffen , Brenner David , Ruf Wolfgang , Weiland Ulrike , Mayer Benjamin , Schuster Joachim , Dorst Johannes , Tumani Hayrettin , Ludolph Albert 
Published: November 2023

Abstract
OBJECTIVE
Neurofilament light (NfL) and phosphorylated heavy chains (pNfH), established as diagnostic and prognostic biomarkers in hospital-based amyotrophic lateral sclerosis (ALS) cohorts, are now surrogate markers in clinical trials. This study extends their evaluation to a population level, with the aim of advancing their full establishment and assessing the transferability of biomarker findings from controlled cohorts to real‑world ALS populations.
METHODS
We measured serum NfL and pNfH levels in all ALS patients (n=790) and general population controls (n=570) with available baseline samples participating in the epidemiological ALS Registry Swabia, providing platform-specific (ELLATM) reference data and Z-scores for controls, as well as reference data, disease-specific Z-scores and longitudinal data in ALS. We evaluated the diagnostic and prognostic utility of neurofilaments and quantified the impact of ALS-related factors and non-ALS confounders.
RESULTS
Neurofilaments showed high diagnostic and prognostic utility at the population level, with NfL superior to pNfH. The novel concept of a population-based ALS Z‑score significantly improved the prognostic utility compared to absolute raw values. Both biomarkers increased more strongly with age in controls than in ALS, and age adjustment improved diagnostic accuracy. Our data show that disease progression rates, ALS phenotype, BMI and renal function need to be considered when interpreting neurofilament levels; longitudinal neurofilament levels were generally stable in individual patients, especially when adjusted for age and baseline levels.
INTERPRETATION
Population-based assessment enhances the utility of particularly serum NfL as a diagnostic and prognostic biomarker in ALS and improves the translation of findings from controlled cohorts to real-world populations.
Combining episodic and semantic memory: a brain-inspired approach for video captioning
Authors: Yao Xiao , Yuan Zhaohui , Gu Min 
Published: November 2023

Abstract
Traditional video captioning algorithms mainly rely on detecting objects in the video, realizing the simulation of episodic memory. However, these methods neglect the discussion of the implicit relation between objects, lacking the simulation of semantic memory. In this paper, we discuss the mechanisms of episodic and semantic memory and their relations in the human brain, and a semantic memory branch is added. By using a semantic graph linking to an external knowledge base, the interaction mechanism between episodic and semantic memory is modeled to enhance and inhibit the relations between the semantics of the learned video. We evaluate the effectiveness of our method on public benchmarks (Microsoft Research Video Description Corpus (MSVD) and Microsoft Research Video to Text (MSRVTT)). Extensive experiments demonstrate that our model outperforms general state-of-the-art methods and effectively improves the effect of content understanding in videos.
In situ expression of TNF-α and IL-10 in human dermatophytosis lesions due to Trichophyton rubrum
Authors: Reis Ana Paula Carvalho , Correia Franciele Fernandes , Celestrino Giovanna Azevedo , Pagliari Carla , Criado Paulo Ricardo , Lalwani Pritesh Jaychand , Benard Gil , STAFOCKER MARIA DA GLÓRIA SOUSA , Sousa Maria Gloria Teixeira 
Published: November 2023

Abstract

Dermatophytosis is a very common superficial mycosis, but there are few studies about the human immune response to dermatophytes. We aim to analyze the in situ expression of TNF-α and IL-10 in human dermatophytosis. Expression of TNF-α and IL-10 were evaluated in skin samples from 10 patients with dermatophytosis and 12 healthy subjects using an immunohistochemistry assay. TNF-α and IL-10 were significantly elevated in lesions from patients with dermatophytosis compared to healthy controls. These data illustrate the balance of pro- and anti-inflammatory cytokines suggesting Trichophyton rubrum infection could control the local immune response.
Feasibility of blinding spinal manual therapy interventions among participants and outcome assessors: protocol for a blinding feasibility trial
Authors: Laguna Javier Muñoz , Kurmann Astrid , Hofstetter Léonie , Nyantakyi Emanuela , Clack Lauren , Bang Heejung , Foster Nadine E. , Braun Julia , Puhan Milo A. , Farshad Mazda , Hincapié Cesar A 
Published: November 2023

Abstract

Introduction: Blinding is a methodologically important aspect in randomised controlled trials, yet frequently overlooked in trials of spinal manual therapy interventions for back pain. To help inform the blinding methods of a future, double-sham-controlled trial comparing spinal manual therapy and nerve root injection for sciatica, we set four objectives: (1) to assess the feasibility of blinding participants, randomly allocated to an active or sham-control spinal manual therapy intervention protocol, (2) to assess the feasibility of blinding outcome assessors within the trial, (3) to explore the influence of spinal manual therapy experience and low back pain on blinding, and (4) to explore factors contributing to perceptions about intervention assignment among participants and outcome assessors. Methods and analysis: Two-parallel-group, single-centre, sham-controlled, methodological blinding feasibility randomised trial. We will recruit between 60 and 100 adults with or without back pain and with or without experience of spinal manual therapy from Zurich, Switzerland. Participants will be randomised to either an active spinal manual therapy, or a sham-control spinal manual therapy protocol—both interventions delivered over two study visits, one to two weeks apart. The primary outcome is participant blinding using the Bang blinding index within each intervention arm immediately after each of the two study visits. Secondary outcomes are participant study-level blinding using the James blinding index, outcome assessor blinding (Bang and James blinding indices), self-reported factors influencing perceived intervention assignment among participants and outcome assessors, and participant-reported credibility and expectancy of study interventions. Other outcomes—included to mask the study objective from participants—include lumbar spine range of motion, self-rated general health, satisfaction with care, back flexibility, pain intensity and function. Treating clinician outcomes include intervention delivery fidelity and self-rated quality of intervention delivery. Ethics and dissemination: The independent ethics commission of Canton Zurich granted ethical approval for this study (KEK 2023 − 00381). Written informed consent will be obtained from all participants. Findings will be disseminated in scientific conferences and a peer-reviewed publication and inform the blinding component of a future randomised controlled trial comparing spinal manual therapy and nerve root injection for sciatica—the SALuBRITY trial. Trial registration number: NCT05778396
Comparison of efficacy and safety of first-line treatment options for unresectable stage III non-small cell lung cancer: a retrospective analysis
Authors: Zhao Luqing , Zhao Zhiting , Yan Xiaoqi , Wu Fei , Sun Ning , Guo Renhong , Hu Xiao , Feng Jifeng , Yu Shaorong 
Published: November 2023

Abstract
Background:Based on PACIFIC trail, durvalumab as consolidation therapy following concurrent chemoradiotherapy (cCRT) has been a new standard treatment for unresectable stage III non-small cell lung cancer (NSCLC). In clinical applications, there are heterogeneous adjustments or novel strategies following specialized discussions in experienced multidisciplinary teams. This study retrospectively compared the efficacy and safety of different first-line treatments for unresectable stage III NSCLC.
Methods:We retrospectively analyzed 397 patients who received first-line treatment for unresectable stage III NSCLC. Comparisons and statistical analyses of treatment were made in terms of efficacy and safety. Adverse events and responses were assessed using CTCAE v5.0 and RECIST v1.1. The progression-free survival (PFS) wasestimated using the Kaplan-Meier method or Cox survival regression model and compared using the log-rank test.
Results:In wild type driver genes group, the objective response rate (ORR), disease control rate (DCR) and median PFS (mPFS) were prolonged in the radiotherapy group than in the non-radiotherapy group (ORR: 50.94% vs. 30.06%, p＜0.001; DCR: 98.11% vs. 80.37%, p＜0.001; mPFS: 21.00 vs. 8.20 months, p＜0.001). The incidence of pneumonia at any grade in the radiotherapy group was higher than that in the non-radiotherapy group (9.43% vs. 2.45%, p=0.008). In the radiotherapy group, the chemoradiotherapy (CRT) plus immunotherapy subgroup had longer mPFS than the CRT subgroup, with increased toxicity at any grade (24.60 vs. 17.90 months, p=0.025; 83.17% vs. 65.52%, p=0.011). In the non-radiotherapy group, the DCR and mPFS were higher in the chemotherapy plus immunotherapy subgroup than in the chemotherapy subgroup, with increased toxicity at any grade (DCR: 93.67% vs. 67.86%, p＜0.001; mPFS: 13.53 vs. 5.07 months, p＜0.001; 68.35% vs. 41.67%, p=0.001). In mutant driver genes group, the efficacy did not significantly differ among radiotherapy subgroup, targeted therapy subgroup and radiotherapy plus targeted therapy subgroup (ORR: p=0.633; mPFS: p=0.450).
Conclusions: For unresectable stage III NSCLC patients with wild type driver genes, the combination of radiotherapy and immunotherapy in the initial treatment were essential to significantly improve the efficacy. For patients with mutant driver genes, radiotherapy, targeted therapy, and the combination of radiotherapy and targeted therapy showed similar short-term efficacy.
Transcriptomic changes in the testes and brain associated with sperm competition risk in male zebra finches
Authors: Riyahi Sepand , Liebermann-Lilie Navina D. , Jacobs Arne , Korsten Peter , Mayer Uwe , Schmoll Tim 
Published: November 2023

Abstract

We investigated how phenotypic plasticity induced by experimentally manipulated sperm competition risk is reflected in transcriptomic profiles of testes and two brain areas (posterior pallium and optic tectum) in breeding male zebra finches (Taeniopygia guttata). Based on an exceptionally large sample of 59 individual transcriptomes, we compared two experimental groups: males held in single pairs versus two pairs per breeding cage. We found tissue-specific differential gene expression in all three tissues at the level of gene co-expression network modules. The treatment affected multiple cellular functions in the testes, which can be associated with germ cell production and modification. Moreover, neural and glial brain cell changes indicate phenotypic adjustment of male zebra finch behaviour to the social environment. Finally, individual co-expression modules correlated with individual behavioural phenotypes and hormonal profiles. Our pre-registered study shows the importance of transcriptomic plasticity for phenotypic adjustment to male-male competition in zebra finches.

Peter Korsten, Uwe Mayer and Tim Schmoll share the last authorship.
Sense of social integration and academic achievement in adolescent students: Quasi-experimental estimates of reciprocal effects
Authors: Sakellariou Chris 
Published: November 2023

Abstract

This study investigated the role of endogeneity of variables of interest and associated biases when deriving effect estimates in the relationship between perceptions of social integration and students’ academic achievement. The dataset used is a large sample of 15-year-old students from the 2018 PISA surveys. Following an Instrumental Variable (IV) approach, paying particular attention to testing the suitability of instruments used, I derived bias-corrected effect estimates which are generally larger than conventional regression estimates. This was especially the case for female students in the direction from sense of social integration to reading literacy. Reciprocal effects were also established, with small to medium effect sizes in the direction from reading and mathematics scores to sense of social integration, for both male and female students. Clear policy implications emerge, targeting heterogeneous pairs/groups of students with respect to their social integration in school, as well as their academic performance.