bluuebunny/crossref_metadata_2025_split huggingface dataset:
Zombie papers, the Data Deluge column
Authors: Frederick Donna Ellen 
Published: November 2023

Purpose
The purpose of this paper is to discuss how retracted scientific papers become zombie papers and why they are problematic and to encourage librarians to become active in addressing these problems.

Design/methodology/approach
This paper explains what zombie papers are, how they are created and the potential impact they can have on the body of scientific literature. It explains how and why they are different than other common types of misleading scientific publications. It also explores recent developments such as the growth of artificial intelligence (AI) technologies and changes to organizations that make data about paper retractions available.

Findings
While journal retractions are as old as scientific publishing itself, the seriousness of retractions persisting and being used in the body of scientific literature has recently been recognized as a serious concern. The rise of new AI technologies such as ChatGPT has made the presence of zombie papers in the data used to train large language models (LLMs) extremely concerning.

Originality/value
While librarians are well-aware of journal retractions and most include information about them in their information literacy training, concerns around zombie papers and their potential presence in the data used to train LLMs will likely be a new consideration for most.
Postbiotics: an innovative approach to increase shelf life and quality of foods
Authors: Nikravan Leila , Zamanpour Setayesh , Noori Seyyed Mohammad Ali 
Published: November 2023

Purpose
The purpose of this paper is to provide an overview of the antimicrobial and antioxidant properties of postbiotics and the use of postbiotics to increase the shelf life and quality of food.

Design/methodology/approach
In this review paper, all articles from five electronic databases containing Google Scholar, Web of Science, PubMed, Scopus and Science Direct were considered and selected according to the purpose of the study.

Findings
In addition to improving food safety and increasing its shelf life, natural food preservation using biological preservatives also has a positive effect on improving consumer health. As a result, protection using natural antioxidants and antimicrobial agents seems essential. Postbiotics, having favorable characteristics such as nontoxicity, long shelf life and ease of standardization and transportation, are known as suitable antioxidant and antimicrobial, and there is an interest in making antioxidant and antimicrobial active films containing postbiotics to delay spoilage, increase the shelf life of perishable foods without changing their sensory characteristics.

Originality/value
Postbiotic refers to all soluble factors that are either secreted from living probiotic cells or released after cell lysis. These compounds include enzymes, peptides, polysaccharides, organic acids, teichoic acids and cell surface proteins, and their effects have been proven to improve some human and animal diseases. Probiotic bacteria must survive unfavorable conditions such as processing, storage, distribution, preparation and the digestive system to exert their health-giving effects, whereas their metabolites (postbiotics) have overcome these adverse conditions well and may be a good substitute for probiotics.
Modeling wine consumer typology, motivation, satisfaction and loyalty: Wine tourism destination visitors vs residents in Florida
Authors: Tasci Asli D.A. , Wei Wei , Back Robin M. 
Published: November 2023

Purpose
This study aimed to identify both visitors’ and residents’ general wine consumer typology as well as their typology specific to a wine destination, Florida, and investigated the influences of these typologies on consumer motivation to visit a winery in Florida and their motivations’ influences on their satisfaction with the winery visit and loyalty in the way of likelihood to revisit.

Design/methodology/approach
Two studies were conducted to identify the wine consumer typology and its influences, one with residents of a wine destination and one with its visitors. In both studies, the same cross-sectional survey design was conducted. The survey was designed using the survey design tools of Qualtrics.

Findings
Study results showed similar general wine consumer typology for both visitors and residents but slight differences in the destination-specific wine consumer typology. Results also revealed differences in the influences of these typologies on motivation, with different influences on satisfaction and loyalty for the two segments.

Originality/value
Even though consumer typologies have been discussed in tourism destination decision-making and choice, consumer typology in wine destination consumption has been lacking in the literature. To the best of the authors’ knowledge, this is the first study to identify both visitors’ and residents’ general wine consumer typology as well as their typology specific to a wine destination, Florida, and to investigate the influences of these typologies on consumer motivation to visit a winery in Florida and their motivations’ influences on their satisfaction with the winery visit and likelihood to revisit.
Revenge tourism value co-destruction: the role of resilience and altruism
Authors: Deng Chengdan , Shen Huawen , Yan Qi 
Published: November 2023

Purpose
Following the trait activation theory, this study aims to shed light on the influence of tourists’ personality traits on their value co-destruction (VCD) behavior in “revenge tourism”, considering the moderating effect of perceived risk as the environment factor.

Design/methodology/approach
A pilot study (n = 204) was first conducted to check the reliability of the measurement scale and remove inappropriate items. Thereafter, a convenience sampling method was used for data collection in the main survey among people (n = 330) who have at least one traveling experience after COVID-19 tourism restrictions have been terminated. Confirmatory factor analysis and structural equation modeling (SEM) were performed for data analysis to testify the theoretical framework proposed.

Findings
Results of SEM analysis show that both resilience and altruism of tourists reduced their VCD behavior. What’s more, perceived risk has been found to moderate the relationship between altruism and VCD behavior. As perceived risk increased, the negative impact of altruism on VCD behavior would be weaken.

Originality/value
VCD have been recently emphasized as a key block to the development of tourism industry. This study examines VCD behavior following the trait activation theory. Results of the study can provide new insights on how to mitigate VCD, which would contribute to the preparation for future tourism crisis management, such as the next pandemic.
Evaluating the influences of floral traits and pollinator generalism on α and β diversity of heterospecific pollen on stigmas
Authors: Ashman Tia‐Lynn , Wei Na 
Published: November 2023

Abstract

Pollinator sharing often leads to receipt of heterospecific pollen (HP) along with conspecific pollen. As a result, flowering plants can accumulate diverse communities of HP on stigmas. While variation in HP diversity is an important selective force contributing to flowering plant fitness, evolution and community assembly, our understanding of the extent and drivers of heterogeneity of HP diversity is limited.

In this study, we examined the species compositions and abundances of ~1000 HP communities across 59 co‐flowering plant species in three serpentine seep communities in California, USA. We evaluated the variation in HP diversity (γ diversity) across plant species in each seep and asked whether the variation in HP γ diversity was caused by variation in HP diversity within stigmas (α diversity) or HP compositional variation among stigmas (β diversity) due to the replacement of HP species (turnover) or their loss (nestedness) from one stigma to another. We further evaluated the potential drivers of variation in HP α and β diversity using phylogenetic structural equation models.

We found that variation in HP γ diversity across plant species was driven strongly by differences among species in HP α diversity and to a lesser extent by HP β diversity. HP community turnover contributed more to HP β diversity than nestedness consistently across plant species and seeps, suggesting a general pattern of HP compositional heterogeneity from stigma to stigma. The phylogenetic structural equation models further revealed that floral traits (e.g., stigma area, stigma‐anther distance, stigma exposure) and floral abundance were key in determining HP α diversity by influencing HP abundance (load size), while floral traits and abundance showed variable impact on HP β diversity (turnover and nestedness). Pollination generalism contributed relatively less to HP‐α and β diversity.

These findings disentangle the heterogeneity in HP diversity at different levels, which is essential for understanding the process underlying patterns of HP receipt in plant communities. That floral traits drive the heterogeneity in HP diversity points to additional avenues by which HP receipt may contribute to plant evolution.

Read the free Plain Language Summary for this article on the Journal blog.
Association of remnant cholesterol and newly diagnosed early‐onset type 2 diabetes mellitus in Chinese population: A retrospective cross‐sectional study
Authors: Dong Wenjing , Yan Shiju , Chen Han , Zhao Jian , Zhang Zengqiang , Gu Weijun 
Published: November 2023

AbstractBackgroundWith the increasing incidence of diabetes worldwide, patients diagnosed with diabetes has been getting younger. Previous studies have shown that high remnant cholesterol (RC) level leads to an increased risk of cardiovascular disease events. However, the relationship between RC levels and newly diagnosed early‐onset type 2 diabetes mellitus (T2DM) is unknown. This study aimed to explore the association between RC and newly diagnosed early‐onset T2DM.MethodsA total of 606 patients newly diagnosed with early‐onset T2DM and 619 gender‐matched subjects with normal blood glucose levels were retrospectively enrolled in this study. All T2DM patients showed onset age of 18–40 years. Binary logistic regression analysis was performed to analyze independent risk factors and receiver operating characteristic (ROC) analysis was used to explore the predictive value of RC and other unconventional lipids. Moreover, the correlation between RC and insulin resistance in patients with newly diagnosed early‐onset T2DM was also examined with binary logistic regression analysis and Spearman correlation analysis.ResultsIncreased RC level was an independent risk factor for early‐onset T2DM (p < .05). The area under the curve on ROC analysis of RC was 0.805, 95% confidence interval (CI) was 0.781 ~ 0.826, sensitivity was 82.18% and specificity was 66.24%, which showed higher predictive value than those of triglyceride/high‐density lipoprotein cholesterol (TG/HDL‐C) ratio and total cholesterol (TC)/HDL‐C ratio. Cutoff value of RC was 0.32 mmol/L. Level of RC in early‐onset T2DM patients with moderate or severe insulin resistance was significantly higher than that in patients with mild insulin resistance (p < .0001). No difference in RC levels was found between patients with moderate and severe insulin resistance (p > .05). RC was still correlated with insulin resistance after adjusting the conventional lipid parameters (TG, TC, HDL‐C, and low‐density lipoprotein cholesterol) using partial correlation analysis.ConclusionRC level was higher in patients with early‐onset T2DM and was correlated to the degree of insulin resistance as well. Patients aged 18–40 years with RC >0.32 mmol/L showed an increased risk of developing T2DM.
Demand uncertainty, inventory, and cost structure
Authors: Chang Xin , Kwok Wing Chun , Wong George 
Published: November 2023

AbstractBuilding on Banker, Byzalov, and Plehn‐Dujowich's (2014, The Accounting Review, 89(3), 839–865) congestion cost theory, we model firms' trade‐off between a rigid cost structure and a high inventory level to reduce the congestion costs caused by uncertain demand. We demonstrate that firms with a higher inventory level adopt a less rigid cost structure, but the effect of cost structure on inventory is theoretically ambiguous. Using a large sample of manufacturing firms in the United States, we empirically investigate the dynamic interdependence between cost structure and inventory choices. Our results reveal that cost structure rigidity and inventory are negatively associated with each other over time, suggesting that they serve as substitutes in tackling demand uncertainty. Further analysis demonstrates that firms favor higher inventory levels over more rigid costs when inventory‐carrying costs decrease, fixed input costs increase, or downside risk escalates.
Latent transforming growth factor beta binding protein 4: A regulator of mitochondrial function in acute kidney injury
Authors: Neikirk Kit , Ume Adaku C. , Prasad Praveena , Marshall Andrea G. , Rockwood Jananie , Wenegieme Tara‐Yesomi , McMichael Kelia E. , McReynolds Melanie R. , Williams Clintoria R. , Hinton Antentor 
Published: November 2023

AbstractRecently, latent transforming growth factor beta binding protein 4 (LTBP4) was implicated in the pathogenesis of renal damage through its modulation of mitochondrial dynamics. The seminal article written by Su et al. entitled “LTBP4 (Latent Transforming Growth Factor Beta Binding Protein 4) Protects Against Renal Fibrosis via Mitochondrial and Vascular Impacts” uncovers LTBP4's renoprotective role against acute kidney injury via modulating mitochondrial dynamics. Recently, LTBP4 has emerged as a driver in the mitochondrial‐dependent modulation of age‐related organ pathologies. This article aims to expand our understanding of LTBP4's diverse roles in these diseases in the context of these recent findings.
Impact of diffused versus vasculature targeted DNA damage on the heart of mice depleted of telomeric factor Ft1
Authors: La Torre Mattia , Centofante Eleonora , Nicoletti Carmine , Burla Romina , Giampietro Alessandro , Cannistrà Federica , Schirone Leonardo , Valenti Valentina , Sciarretta Sebastiano , Musarò Antonio , Saggio Isabella 
Published: November 2023

AbstractDNA damage is emerging as a driver of heart disease, although the cascade of events, its timing, and the cell types involved are yet to be fully clarified. In this context, the implication of cardiomyocytes has been highlighted, while that of vasculature smooth muscle cells has been implicated but not explored exhaustively. In our previous work we characterized a factor called Ft1 in mice and AKTIP in humans whose depletion generates telomere instability and DNA damage. Herein, we explored the effect of the reduction of Ft1 on the heart with the goal of comparatively defining the impact of DNA damage targeted to vasculature smooth muscle cells to that of diffuse damage. Using two newly generated mouse models, Ft1 constitutively knocked out (Ft1ko) mice, and mice in which we targeted the Ft1 depletion to the smooth muscle cells (Ft1sm22ko), it is shown that both genetic models display cardiac defects but with differences. Both Ft1ko and Ft1sm22ko mice display hypertrophy, fibrosis, and functional heart defects. Interestingly, Ft1sm22ko mice have early milder pathological traits that become manifest with age. Significantly, the defects of Ft1ko mice, including the alteration of the left ventricle and functional heart defects, are rescued by depletion of the DNA damage sensor p53. These results point to Ft1 deficiency as a driver of cardiac disease and show that Ft1 deficiency targeted to vasculature smooth muscle cells generates a pre‐pathological profile exacerbated by age.
LEF1 isoforms regulate cellular senescence and aging
Authors: Jia Minxue , Sayed Khaled , Kapetanaki Maria G. , Dion William , Rosas Lorena , Irfan Saad , Valenzi Eleanor , Mora Ana L. , Lafyatis Robert A. , Rojas Mauricio , Zhu Bokai , Benos Panayiotis V. 
Published: November 2023

AbstractThe study of aging and its mechanisms, such as cellular senescence, has provided valuable insights into age‐related pathologies, thus contributing to their prevention and treatment. The current abundance of high‐throughput data combined with the surge of robust analysis algorithms has facilitated novel ways of identifying underlying pathways that may drive these pathologies. For the purpose of identifying key regulators of lung aging, we performed comparative analyses of transcriptional profiles of aged versus young human subjects and mice, focusing on the common age‐related changes in the transcriptional regulation in lung macrophages, T cells, and B immune cells. Importantly, we validated our findings in cell culture assays and human lung samples. Our analysis identified lymphoid enhancer binding factor 1 (LEF1) as an important age‐associated regulator of gene expression in all three cell types across different tissues and species. Follow‐up experiments showed that the differential expression of long and short LEF1 isoforms is a key regulatory mechanism of cellular senescence. Further examination of lung tissue from patients with idiopathic pulmonary fibrosis, an age‐related disease with strong ties to cellular senescence, revealed a stark dysregulation of LEF1. Collectively, our results suggest that LEF1 is a key factor of aging, and its differential regulation is associated with human and murine cellular senescence.
Endodontic–orthodontic interactions: a review and treatment recommendations
Authors: Parashos P 
Published: November 2023

ABSTRACTThe literature is replete with articles describing the many and varied interactions between endodontic treatment and orthodontic tooth movement (OTM), often reporting conflicting views and findings, which creates confusion for clinicians. Original research and review articles have described aspects such as apical root resorption and potential pulpal complications of teeth related to OTM. Some interactions are of relatively minor clinical significance, whilst others may have adverse consequences. A history of dental trauma before or during OTM further complicates the interactions. This review re‐assesses the historical literature on endodontic‐orthodontic interactions in light of more recent research and presents guidelines for managing clinical situations involving both disciplines. © 2023 Australian Dental Association.
Embryonic development of the chick pineal gland throughout the incubation periods
Authors: Colakoglu Fatma , Selcuk Muhammet Lutfi 
Published: November 2023

AbstractBirds have a very different pineal gland structure morphologically and cytologically. The structure of the organ shows significant changes during the incubation periods. This study, which follows the embryological development of the pineal gland and makes histomorphometric measurements of the cellular elements that make up the gland parenchyma, is a current reference for studies in these areas. These brains were taken from 24 Babcock White Leghorn chick embryos on the 10th, 13th, 16th and 21st days of incubation. At 10th embryonic day, the pineal recess was in the structure of an elongated pineal canal. Solid rosette‐shaped cell clusters were transforming into round vesicles with a small lumen. These vesicles had developed into larger, oval‐shaped follicles with a well‐defined central lumen. On 13th day, it was observed that the number and development of follicles increased considerably. The pineal gland showed a follicular‐solid structure in 16th day embryos. While the mean follicle diameter was determined as 123.46 ± 13.28 μm on the 10th embryonic day, the highest value was measured as 187.62 ± 7.37 μm on the hatching day (p < 0.05). While the mean follicle area had the lowest value in the 10th day embryos, it was determined that this value gradually increased compared to the advancing embryonic days (p < 0.05). As conclusion, it is thought that this study provides new data to the literature about pineal gland development by monitoring the histological and histomorphometric developments of chick pineal gland in different incubation periods.
Participation and commercialization in producer cooperatives: Insights on the role of cooperative functioning and equity strategies
Authors: Cheyo Esther J. , Nyuyki Mainimo Edmond , Okello Daniel M. , Odongo Walter , Kalule Stephen W. 
Published: November 2023

AbstractIn sub‐Saharan Africa, there are growing calls for policy reforms to revive the farmer cooperative movement. However, questions remain over whether farmer participation in agricultural cooperatives brings the desired innovation for markets and commercialization. This study uses a sample of 206 farmers from northern Uganda to examine what drives farmer participation and commercialization among members of groundnut producer cooperatives. Results from a two‐stage Heckman regression reveal that cooperative functioning in the form of hiring equipment to farmers, value addition, farmer training, and product quality assessment drives farmer participation in cooperative business. The study also shows that equity strategies, notably through subscription fees and farm‐inputs supply negatively impact commercialization among cooperative participant farmers. This study deepens the literature on cooperatives pinpointing the role of cooperative services in farmer participation and how stringent equity strategies reduce farmer commercialization among cooperative participants. We call for policy interventions that prioritize capacity building of producer cooperatives for improved functioning and better provision of services. This approach will enable these cooperatives to be effectively harnessed for market innovation.
UMG1/CD3ε‐bispecific T‐cell engager redirects T‐cell cytotoxicity against diffuse large B‐cell lymphoma
Authors: Caracciolo Daniele , Polerà Nicoletta , Belmonte Beatrice , Conforti Francesco , Signorelli Stefania , Gulino Alessandro , Staropoli Nicoletta , Tuccillo Franca Maria , Bonelli Patrizia , Juli Giada , Grillone Katia , Ascrizzi Serena , Cirillo Maria , Migale Leonardo , Ballerini Andrea , Pelizon Cristina , Di Martino Maria Teresa , Tagliaferri Pierosandro , Riillo Caterina , Tassone Pierfrancesco 
Published: November 2023

SummaryUMG1 is a unique epitope of CD43, not expressed by normal cells and tissues of haematopoietic and non‐haematopoietic origin, except thymocytes and a minority (<5%) of peripheral blood T lymphocytes. By immunohistochemistry analysis of tissue microarray and pathology slides, we found high UMG1 expression in 20%–24% of diffuse large B‐cell lymphomas (DLBCLs), including highly aggressive BCL2high and CD20low cases. UMG1 membrane expression was also found in DLBCL bone marrow‐infiltrating cells and established cell lines. Targeting UMG1 with a novel asymmetric UMG1/CD3ε‐bispecific T‐cell engager (BTCE) induced redirected cytotoxicity against DLBCL cells and was synergistic with lenalidomide. We conclude that UMG1/CD3ε‐BTCE is a promising therapeutic for DLBCLs.