bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative cross‐sectional study of socio‐psychological orthodontic needs and oral habits in Autism Spectrum Disorder
Authors: da Silva Gustavo Correia Basto , Firmino Ramon Targino , Souto Nóbrega Waleska Fernanda , Nogueira Ana Beatriz Dantas , d’Ávila Sérgio 
Published: November 2023

AbstractObjectiveThis cross‐sectional study analyzed the socio‐psychological need for orthodontic treatment in children and adolescents with and without Autism Spectrum Disorder (ASD) and its association with deleterious oral habits.MethodsChildren/adolescents aged 6–14 years old, with and without ASD, and their respective caregivers were included. Caregivers completed a questionnaire addressing children and adolescents' deleterious oral habits. To assess the socio‐psychological need for orthodontic treatment, we utilized the aesthetic component of the Index of Orthodontic Treatment Needs (IOTN). Caregivers and an orthodontist independently used the standardized IOTN aesthetic attractiveness scale containing ten intraoral photographs and compared them with the most similar condition of the child/adolescent. Data collection occurred at two universities in northeastern Brazil and at an ASD referral center. Statistical analyses encompassed descriptive statistics, Shapiro‐Wilk, Kruskal‐Wallis, Mann‐Whitney, and Chi‐squared tests with linear trend (α5%).ResultsThe study involved 144 participants, evenly divided into two groups (ASD and non‐ASN). The ASD group showed higher average IOTN‐AC scores as evaluated by both professionals (mean score = 4.78 [± 2.34], p = .182) and caregivers (mean score = 4.31 [± 2.71], p = .992). Caregivers reported notably elevated IOTN‐AC scores in cases where onychophagy was absent (p = .049).ConclusionsPatients with ASD are indicated as having a relatively higher socio‐psychological need for orthodontic treatment.
Marine biomaterials in biomedical nano/micro-systems
Authors: Wang Yanan , Chen Long , Wang Yuanzheng , Wang Xinyuan , Qian Deyao , Yan Jiahui , Sun Zeyu , Cui Pengfei , Yu Liangmin , Wu Jun , He Zhiyu 
Published: November 2023

AbstractMarine resources in unique marine environments provide abundant, cost-effective natural biomaterials with distinct structures, compositions, and biological activities compared to terrestrial species. These marine-derived raw materials, including polysaccharides, natural protein components, fatty acids, and marine minerals, etc., have shown great potential in preparing, stabilizing, or modifying multifunctional nano-/micro-systems and are widely applied in drug delivery, theragnostic, tissue engineering, etc. This review provides a comprehensive summary of the most current marine biomaterial-based nano-/micro-systems developed over the past three years, primarily focusing on therapeutic delivery studies and highlighting their potential to cure a variety of diseases. Specifically, we first provided a detailed introduction to the physicochemical characteristics and biological activities of natural marine biocomponents in their raw state. Furthermore, the assembly processes, potential functionalities of each building block, and a thorough evaluation of the pharmacokinetics and pharmacodynamics of advanced marine biomaterial-based systems and their effects on molecular pathophysiological processes were fully elucidated. Finally, a list of unresolved issues and pivotal challenges of marine-derived biomaterials applications, such as standardized distinction of raw materials, long-term biosafety in vivo, the feasibility of scale-up, etc., was presented. This review is expected to serve as a roadmap for fundamental research and facilitate the rational design of marine biomaterials for diverse emerging applications.
Graphical Abstract
The top Bulgarian contributions to sunflower breeding
Authors: Hristova-Cherbadzhi Miroslava 
Published: November 2023

Abstract
The sunflower (Helianthus annuus L.) is a fundamental oil-yielding culture for Bulgaria and the world and thus, special attention is paid to it. Various selection methods have been used over the years and as a result of successful breeding programs new sunflower forms, lines (В/А and R) and hybrids (oil and confectionery type) were created in Bulgaria. Some of these new forms have new plant architectonic, different vegetation periods, seeds with different sizes and coloration, high combining ability, resistance to diseases, the parasite Broomrape and some herbicides, high seed oil and fatty acid content, genes for restoration of fertility (Rf genes), and different types of cytoplasmic male sterility (CMS).
DEVELOPMENT OF CUMULATIVE RAINFALL THRESHOLD FOR LANDSLIDE OCCURRENCE IN PENINSULAR MALAYSIA
Authors: Ali Supiah , Kasim Norhidayu , Saiful Anuar Afiq Aiman , Ruslan Muhammad Imran , Wan Azahar Wan Nur Aifa , Ramli Ahmad Bukhari 
Published: November 2023

Significant issues related to landslides are exposed tremendously in Peninsular Malaysia which have an impact on human beings, animals as well as properties. Reported over twenty-eight significant landslides taking place between 1993 and 2011 which resulted in more than 100 deaths in total. Most of the landslides are the consequences of accumulation of water in underground soil which is connected to rainfall threshold. To establish an empirical Cumulative-Duration threshold through linear regression, analysis of 69 landslide incidents undertaken as well as rainfall data sourced from Public Works Department (PWD) and Department of Irrigation and Drainage (DID) were collected. A comprehensive assessment of all gathered parameters conducted to achieve the confidential purpose of this research which is to determine the threshold for cumulative rainfall event duration which can be utilized in early warning systems and planning for future safety measures. Thus, correlation between rainfall patterns and landslide events are observed. Cumulative rainfall threshold produced an equation E = with identical range of event duration 1 < D < 2448 h which acts as a critical line of landslide occurrences. Validation of threshold was revised using recent landslide cases to acquire new threshold values to represent current rainfall induced landslides. The threshold serves as an early warning mechanism and planning to protect lives and property.
Adopting Project Based Learning in Translation Class to Facilitate Translator Emergent Competences
Authors: Hariyanto Sugeng , Suyono Achmad , Maulidiyah Fitrotul , Mustain Kun 
Published: November 2023

Background:
The teaching of language-related skills in universities and colleges needs to equip students with relevant skills suitable for work after graduation. One way of building studentsâ€™ skills to meet the related industryâ€™s demands is by adopting project based learning (PBL) in teaching. There have been several studies on the topic of PBL in translation courses, but none of them have provided a step-by-step classroom procedure.
Methodology:
The study was a case study to describe the model of project-based learning adopted in the English Department of one Polytechnic in Java island, Indonesia. The object of the study was the Localization and Transcreation class. The data sources included the teacher and 24 sixth-semester students taking the class. Questionnaires and interview were used for the data collection. The questionnaires were used to know the studentsâ€™ perceived competences. The interview was used to get more information on how the PBL was conducted and studentsâ€™ further opinion about it. Before a class was started, the students were asked to fill in the provided questionnaire on the status of their competence at the time. Then, the PBL was employed to teach the class. After the PBL was done, the students were asked to fill in the same questionnaire to report their competences at the time. The researcher analyzed the results. Finally, an interview was conducted with the teacher and three students who answered the questionnaire most comprehensively.
Findings:
The findings of this study show that PBL could be employed to teach translation in vocational higher education and the students saw PBL positively. Based on the studentsâ€™ opinion, this research found that PBL in the translation class helped students develop their translation skills, teamwork skills, workplace skills, communication skills, and self-confidence.
Conclusion:
In conclusion, PBL employed in the translation class has shown its effectiveness in improving studentsâ€™ translation and other competences.
Originality:
The Ministry of National Education of the Republic of Indonesia has promoted project-based learning. To date, no clear model has been developed for the teaching of translation in Indonesian universities. This article describes project-based learning developed and practiced in a Polytechnic and how students react and the improvement of their competences or skills.
Haydn’s Trumpet Concerto in the Twentieth Century
Authors: Мур Б.Р. 
Published: November 2023

В переводе работы американского ученого и музыканта Брайана Мура представлены интересные факты об истории заново открытого произведения Й. Гайдна для трубы в XX веке. Они имеют не только научный, но и исполнительский интерес. Следуя эмпирическим путем, автор не только рассказывает об истории исполнения, редакций и изданий концерта, но и приходит к переосмыслению самих исполнительских принципов в данном произведении — темпов всех частей концерта, штрихов, артикуляции и динамических оттенков. Тем самым он меняет современные общепринятые представления об интерпретации и исполнении концерта в сторону более аутентичной трактовки, при возросших технических возможностях инструмента.
The translation of a work by the American scholar and musician Brian Moore presents interesting facts about the fate of the rediscovered piece for trumpet by J. Haydn in the 20th century. They are not only of scholarly, but also of performing interest. Following the empirical path, the author considers the history of performance, editions, and publications of the Concerto and comes to rethink the very principles of this work performing – tempi of all movements, articulation, and dynamic nuances. Thus, he changes the modern generally accepted ideas about the interpretation and performance of the Concerto towards a more authentic performance, with increased technical capabilities of the instrument.
El sistema de conductos radiculares de segundos premolares maxilares y mandibulares mediante la técnica de diafanización dental
Authors: Castillo Chacón Andrés Alexander , Lozada Yundun Yessenia Alejandra , Hernández Santander Gladys Rocío , Granda Untuña WWilliam Omar , Aguayza Castro Michelle Estefania 
Published: November 2023

Objetivo: Identificar el sistema de conductos radiculares que presentan los segundos premolares maxilares y mandibulares, utilizando la técnica de diafanización dental. Materiales y métodos: 100 segundos premolares humanos, superiores e inferiores, fueron donados por distintos centros odontológicos de la ciudad de Quito. Los mismos fueron seccionados a nivel amelocementario para disponer de la raíz. Se permeabilizó el conducto radicular con lima K # 10 y se procedió a inyectar tinta china Pelikan ® en la cámara pulpar y conductos radiculares. Para lograr la descalcificación, los dientes se sumergieron en un frasco de vidrio con ácido nítrico al 5%. El proceso de deshidratación consistió en colocar los dientes en alcohol al 80 ,90 y 100%. Finalmente, los dientes deshidratados fueron almacenados en metil salicilato. Resultados: La clasificación tipo I de Vertucci fue predominante en 50 segundos premolares superiores con un total de n=25 (50%) piezas seguida de la clasificación tipo IV n=16 (32%) tipo V n=6 (12%) tipo III n=4 (4%) y clasificación tipo VII n=1 (2%). Los 50 segundos premolares inferiores restantes presentaron la clasificación tipo I de Vertucci en un 74% correspondiente a n=37, seguida de la clasificación tipo IV n=8 (16%) y tipo III n=5 (10%). Conclusión: La diafanización es una técnica que permite observar de forma directa y tridimensional la anatomía interior de los dientes extraídos. En este estudio la clasificación predominante fue la de tipo I de Vertucci, tanto en premolares superiores como inferiores.
Comparative Efficacy of Insulin, Biguanides and Sulfonylureas In The Glycemic Control of Newly Diagnosed Diabetes Mellitus Patients in Rajshahi, Bangladesh
Authors: Zaman Md Saif Zaman , Hassan Parvez Hassan , Islam S M Shahinul Islam , Ullah Md Anayet Ullah , Rabbani Md Golam Rabbani 
Published: November 2023

The goal of the present study was to examine how well three distinct kinds of anti-diabetic drugs- insulin, biguanides and sulfonylureas performed in Bangladeshi patients who had recently been diagnosed with diabetes mellitus. This was an observational study and carried out on 102 patients admitted in different hospitals in Rajshahi, Bangladesh during the study period. Majority (32.02%) respondents belonged to 51-60 years age group, followed by 41-50 years and the least >60 years age group viz. 7.19%. Female preponderance was noticed in the study population where 59.80% were females; whereas 40.20% males. Results of distribution of respondents based on residence and class of anti-diabetic medication use showed in insulin receiving group 66.67% were urban people and 33.33% were rural resident; biguanides receiving groups 64.71% were urban resident and 35.29% were rural resident; sulfonylureas receiving groups 58.82% were urban resident and 41.18% were rural residents. Data on participant’s lifestyle and smoking habit showed lifestyle of 65.70% patients were sedentary and 34.30% were active and according to smoking habit of the patients 14% were smokers while 86% were non-smokers. Family history of DM among the patients showed 17% had familial history and 83% did not have. Data showed that the patients taken insulin, biguanides and sulfonylurea as with BMI were mostly in 18.50 - 24.99 with p-value 0.621. Although no statistically significant difference was noticed among the groups regarding treatment response of three drugs (p = 0.252, 0.284, 0.675 for HbA1c, FBS and PPBS respectively) after 3 months follow-up of medication use and (p = 0.284, 0.323, 0.817 for HbA1c, FBS and PPBS respectively) after 6 months follow-up. However, p-value was not significant but insulin receiving patients had relatively better treatment response than biguanide receiving group than sulfonylurea receiving group at 3rd and 6th month. In insulin receiving group 90.19 % had desired glycemic control. In biguanide receiving group 76.47 % had desired glycemic control. In sulfonylurea receiving group 84.31 % had desired glycemic control. So it appears that insulin provides the best glycemic control followed by sulfonylurea and the biguanides are relativity less potent in glycemic control of newly diagnosed patients in our study area. In this study, the sample size was quite small, which may not represent the whole population and the research used purposeful sampling, which may have skewed the results.
J. Bio-Sci. 31(1): 39-49, 2023
Encrucijadas de la educación universitaria en el marco de las orientaciones de la UNESCO para el siglo XXI
Authors: Casas-Álvarez José 
Published: November 2023

Se abordan los ejes de trabajo que la UNESCO ha delineado para las universidades, con la intención de identificar tanto los vínculos y debates en torno a los escenarios de formación para el siglo XXI. Esto cobra particular relevancia en un contexto que llevó a prácticamente todos los actores involucrados en la educación, a replantearse el lugar de la presencia en las instituciones, en general, pero en la presencialidad educativa en lo particular, como efecto de la pandemia por COVID 19. Esto obligó a repensar la pertinencia y los significados de modelos educativos: digitales, a distancia e híbridos. Se logra advertir una fuerte relación de la UNESCO con el aprovechamiento eficiente y eficaz de las TIC en la educación en general, con particular interés en las universidades. Abriéndose así, debates importantes acerca de la orientación de la formación universitaria, por ejemplo: hacia las sociedades de la información, del conocimiento o de los aprendizajes; hacia los objetivos para el desarrollo sostenible; hacia los ciclos de innovación; hacia la transición económico-ecológica; así como retos antropológicos y civilizatorios, tales como el transhumanismo y la ética tecnológica con el advenimiento de la denominada revolución 4.0.
Modifikasi dan Uji Kinerja Alat Pengering Tipe Rak Model Teta 22 Biji Pala (Myristica Fragrans Houtt) Menggunakan Sumber Panas Gas LPG
Authors: Amiri Nofri Abdul Azis , Longdong Ireine , Tooy Dedie 
Published: November 2023

Penelitian ini bertujuan untuk: 1. Memodifikasi alat pengering tipe rak Model Teta’17, 2. Menguji kinerja alat meliputi suhu, kelembaban udara, kadar air dan laju pengeringan terhadap air. Penelitian ini dilakukan dengan menggunakan metode percobaan untuk peembuatan alat dan analisa data menggunakan metode deskriptif yaitu data dari pengamatan disusun dalam bentuk tabel, kemudian digambarkan dalam bentuk grafik, lalu dideskripsikan. Setiap rak yaitu rak atas dan rak bawah masing-masing menggunakan 500 sampel biji pala. Setiap percobaan dilakukan 2 (dua) kali ulangan. Variabel yang diamati adalah suhu, kelembaban udara, kadar air bahan dan laju pengeringan. Hasil dari penelitian ini modifikasi alat pengering tipe rak Model Teta’17 dengan cara menambahkan cerobong tidak menunjukan adanya kondensasi pada bagian permukaan dinding alat. Dari hasil penelitian rata-rata suhu rak atas sebesar 53°C dan rata-rata suhu rak bawah sebesar 55°C dan rata-rata suhu suhu dalam plenum sebesar 54°C. Rata-rata kelembaban udara dalam plenum sebesar 70%. Rata-rata kadar air biji pala rak atas sebesar 10.2% dan rak bawah 8.7%. Waktu pengeringan yang dibutuhkan untuk mengeringkan biji pala sampai dengan kadar air 8-10% yaitu 11 jam. Laju pengeringan terhdap kadar air ulangan 1 rak atas sebesar 2.55%, rak bawah 2,72% dan ulangan 2 rak atas sebesar 2.65%, rak bawah sebesar 2.75%..
Исторически преглед на дефиницията за редки тумори в контекста на здравните политики
Authors: Костадинов Костадин , Мусурлиева Нина 
Published: November 2023

Злокачествени заболявания като събирателна група от нозологични единици представляват значим социален и здравен проблем. Въпреки това, разглеждането на всички видове рак в една категория при изграждането на здравни политики е поставено под критика. Поради клиничните и епидемиологичните си характеристики, пациентите с редки тумори срещат в по-голяма степен бариери в достъпа си до иновативни медикаменти, съчетано с липса на експертиза в диагностично-лечебния процес. Изграждането на самостоятелни политики за тези пациенти изисква точна дефиниция на понятието.
Настоящият обзор цели да представи хронологичното развитие при дефинирането на понятието за редки тумори в контекста на изграждането на здравни политики в тази област. За целите на обзора е осъществено търсене по ключови думи „rare cancers”, „rare tumors” и „rare neoplasm” в базите данни PubMed/MEDLINE и ScienceDirect и Google Scholar. Откритите статии за организирани в три основни контекста на използване на термина „редки тумори“ – клинично базирани дефиниции; дефиниции, базирани на епидемиологични критерии и дефиниции, използвани в детската онкология.
Палиативно лечение и грижа в контекста на нормотворчеството
Authors: Илиева Антония , Мусурлиева Нина 
Published: November 2023

Необходимостта от предоставяне на палиативни грижи за пациентите и техните семейства е от ключово значение за облекчаването на болките и страданията им, както и за съхраняване на възможността за достойно приключване на земният им път. Липсата на фокус от страна на законодателя за приемането на една цялостна нормативна рамка, която да включва в себе си формите, метода, начина на предоставяне и финансиране на палиативното лечение и грижа за нелечимо болните пациенти, създава усещането за отсъствие на държавата и провокира пациентите и техните семейства сами да търсят подкрепа и помощ за облекчаване на болките и страданията.
Целта на настоящия анализ е да се представи съществуващата нормативната рамка, въз основа на която се предоставя палиативно лечение и грижа в Република България. Да се обобщи изчерпателността на нормативната дефиниция, както и да се направят релевантни препоръки за оптимизация на уредбата, с оглед констатираните празноти в нея. Използван е документален метод за проучване и анализ на научна литература, нормативната уредба и международната практика в областта на палиативното лечение и грижи.
Барух Блумберг – учен в движение и ловец на вируса-убиец
Authors: Кеворкян Ани , Рангелова Ваня 
Published: November 2023

Повече от петдесет години след откриването на вируса на хепатит В (HBV), той продължава да бъде един от най-важните човешки патогени, атакуващ черния дроб. От инфекциозна болест със сериозни последици към настоящия момент вирусният хепатит В се отнася към заболяванията, намиращи се във фаза на епидемиологичен контрол.
Д-р Барух Самюел Блумберг, определян като „учен в движение“, започва своята кариера в търсене на наследствените различия. Изследванията му водят до откриване на нов вирус – HBV. Скоро след доказване на вирусната етиология на HBV, се потвърждава и връзката му с първичния рак на черния дроб. Той създава първата ваксина за предотвратяване на инфекцията. За своя принос Барух Блумберг е удостоен с Нобелова награда за физиология или медицина през 1976 г.
С право откриването на вируса и създаването на сигурна и ефективна ваксина се определят като едно от забележителните научни постижения на XX век.
Дослідження впливу магнітного стану пробивних пуансонів з швидкорізальної сталі на стійкість
Authors: Kindenko Mykolaj 
Published: November 2023

Кінденко М. І. Дослідження впливу магнітного стану пробивних пуансонів з швидкорізальної сталі на стійкість
Робота присвячена дослідженню питань, пов'язаних з дослідженням впливу магнітного стану і полярності робочої частини пробивних пуансонів з швидкорізальної сталі Р6М5 та Р6М5К5 на стійкість після магнітно-імпульсної обробки, що є поєднанням електромагнітного і термодинамічного способів управління нерівноважною структурою речовини. Причини відмов інструментів найчастіше пов'язані не з їх поломкою, а з втратою ними своєї первинної поверхневої конфігурації унаслідок зносу, сколовши, зминання, розтріскування, тобто у зв'язку з руйнуванням або деформації тонких поверхневих шарів металу. Швидкорізальна сталь, як будь-яке тверде тіло, володіє пружним внутрішнім полем, обумовленим реальною дислокаційною структурою. З накладенням магнітного поля на матеріал, на це власне пружне поле накладається пружне поле, викликане магнітострикційною деформацією. В цілому результат магнітної обробки розглядається як прояв ефектів післядії в матеріалах, що знаходяться на кордонах стабільності їх властивостей і підданих дії зовнішнього силового поля. Відмічено, що в результаті дії імпульсного магнітного поля відбувається зміна фізико-механічних властивостей швидкорізальної сталі і інструментальний матеріал стає одноріднішим по структурі. Встановлено що зносостійкість магнітно обробленого інструменту відрізняється від зносу інструменту у вихідному положенні. Розбіжність середніх значень стійкості інструменту у вихідному стані і після магнітної обробки значимо, відповідно обробка імпульсним магнітним полем істотно впливає на стійкість інструменту. Показано, що інструмент повинен мати після магнітної обробки залишкову намагніченість близьку до нуля. Доведено що стійкість інструменту в будь-якому магнітному стані практично не відрізняється, хоча по відношенню до інструменту у вихідному стані вона багато вище.