bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of Aircraft Noise on the Cognitive Function of Elementary School Students in Korea
Authors: Baek Kiook , Park Chulyong , Sakong Joon 
Published: December 2023

Background:
This study evaluated the effects of chronic exposure to aircraft noise on the cognitive functions of Korean elementary school students attending an elementary school around a military airfield and clarified the relationship between noise exposure and cognitive functions.

Methods:
Five schools with average weight equivalent continuous perceived noise levels (WECPNL) of ≥75 dB were selected from four regions in Korea. Each of these schools was matched with a non-exposed school. The Korean Intelligence Test Primary (KIT-P) was used to measure the scores of four subcategories and the intelligence quotient (IQ). The noise exposure groups were divided into high-exposure (WECPNL ≥ 80 dB) and medium-exposure (75 ≤ WECPNL < 80) groups. The period of exposure during the school year was collected. A linear mixed model, with matched pairs of schools, was used for statistical analysis.

Results:
In the multivariable linear mixed model adjusted by possible confounders, the reasoning score was significantly lower in the high-exposure group of students than in the no-exposure group. Other scores and IQ were lower in the noise exposure groups, although these were not statistically significant. The duration of exposure did not show a significant relationship with cognitive functions.

Conclusion:
Chronic exposure to noise from military airfields may influence the cognitive functions, thereby reducing the learning performance of Korean children.
Determining the Relationship Between Noise Sensitivity Levels and Violence Tendencies of Nursing Students
Authors: Karabey Tuba 
Published: December 2023

Purpose:
Exposure to noise has been related to aggressive behavior. As hospital noise may affect nursing students’ psycho-physiological health due to their inexperience, it; 1; is important to investigate possible violent tendencies among them. Since no similar research has been found in the literature, a study has been conducted to investigate the relationship between noise sensitivity and violence tendencies among nursing students.

Methods:
The design of this study was cross-sectional. There were 260 nursing students (61% female) aged 18 to 24 years who filled out the Personal Information Form, Weinstein’s Noise Sensitivity scale, and Violence Tendency scale. We investigated the distribution of students’ noise sensitivity and violence tendencies scores in relation to age, gender, grade, and place of residence. Multiple regression analysis was performed with the noise sensitivity score and possible confounders as independent variables and the severity tendency score as a dependent variable.

Results:
We found smoking to be significantly and positively associated with both noise sensitivity and violent tendencies (P < 0.001). Multiple regression analysis with smoking as a possible confounder revealed that a raise of 0.203 units on the violence tendencies scale may be expected per unit increase on the noise sensitivity scale (P < 0.001).

Conclusion:
Due to the limitations of our study, a possible relationship between nursing students’ noise sensitivity and violent tendencies is tentatively pointed out. More detailed studies are needed to test this assumption.
Online questionnaire on knowledge and risk factors associated with keratoconus
Authors: Juliani Mariana Garcia Herrero , Penhalber Eduarda Eduarda Penhalber , Ferrari Marcia , Rodrigues Pablo Felipe , Moscovici Bernardo Kaplan 
Published: December 2023

Abstract

Purpose:
The purpose of the study is to investigate the impact of body mass index on the progression of this disease and verify patients’ knowledge about the disease and possible forms of treatment.

Methods:
A nonrandomized cross-sectional study analyzing the prevalence of risk factors and patients’ knowledge of keratoconus through a Google forms questionnaire.

Results:
This study demonstrates that most keratoconus patients understand the severity of the disease and maintain regular follow-ups with the ophthalmologist, although many seek information through social networks. We found a correlation between the laterality of the eye with more severe keratoconus and the eye with more rubbing or sleeping with it sunk into the pillow.

Conclusion:
Despite having a small sample of participants, we can notice some statistical significances, such as the correlation between the eye with more severe keratoconus and the laterality of rubbing the eyes or pressing them against the pillow, suggesting a risk factor for the onset or progression of the disease. In addition, we can see that social networks have been widely used as source of information for patients about their disease.
Corneal drug delivery with tattoo technique: A new route for intrastromal cornea administration
Authors: Farah Michelle de Lima , Arbache Samir , Grupenmacher Alex Treiger , Muralha Felipe , Filho Acácio Alves de Souza Lima , Maia Mauricio , Burnier Miguel , Rubens Belfort Jr. 
Published: December 2023

Abstract

Purpose:
The purpose of this study was to describe a new corneal drug delivery technique using a tattoo machine.

Materials and Methods:
Five human eye bank corneas and four rabbits were included in the study. All interventions were performed with a tattoo machine with the following: 60-Hz needling speed, 200-m needling depth, and liner cartridges with seven solid microneedles. Our study was conducted in two stages: an experimental model with ink injection in eye bank corneas and a drug delivery in the corneas of live rabbis. Each cornea received from the eye bank was injected with black and brown inks. Each rabbit received an intrastromal application of biguanide 0.2 mg/mL, triamcinolone 40 mg/mL, or bevacizumab 25 mg/mL. Dry needling was performed in the fourth rabbit. The rabbits were followed clinically for 30 days and were euthanized on day 30. All corneas were photographed before and after the procedure and then processed, stained with H and E, and underwent microscope analysis.

Results:
In the human corneas, pigment was delivered into the corneas with the tattoo machine and the ink remained in the stroma at the desired and stipulated depth. In the rabbits, the treated corneas showed no vascularization, inflammatory cells, or corneal perforation after 30 days of the procedure.

Conclusions:
Corneal drug delivery performed with the tattoo machine was achieved without side effects. Further studies are needed to determine the safety and effectiveness of the intervention in ocular pathologies.
Chat Generative Pretrained Transformer to optimize accessibility for cataract surgery postoperative management
Authors: Waisberg Ethan , Ong Joshua , Masalkhi Mouayad , Zaman Nasif , Sarker Prithul , Lee Andrew G. , Tavakkoli Alireza 
Published: December 2023

Abstract
Cataract surgery is one of the most common surgeries (over 3 million cases) in the United States per year. Consequently, there are multiple diverse and unique postoperative questions in the postoperative course following cataract extraction. To provide rapid and accessible guidance, large language models may help optimize this area in cataract surgery. Chat Generative Pretrained Transformer (GPT) is a complex conversational artificial intelligence model built by OpenAI and trained using an extensive collection of textual data sourced from the internet. The utilization of ChatGPT has a significant potential for diverse applications within various academic disciplines. In the field of medicine, it has the potential to aid health-care professionals, researchers, and patients through a variety of ways. We describe the use of ChatGPT to respond to common postoperative questions associated with cataract extraction. Although further research is required before more widespread acceptance and clinical implementation, we believe that GPT-4 has the potential to improve cataract and refractive postoperative care by providing immediate and accurate responses to patient queries.
Text-to-image artificial intelligence to understand astronaut visual phenomena during spaceflight
Authors: Waisberg Ethan , Ong Joshua , Masalkhi Mouayad , Zaman Nasif , Lee Andrew G. , Tavakkoli Alireza 
Published: December 2023

Abstract
Astronauts have documented visual phenomena during spaceflight. However, given that these are only experienced by the astronaut themselves, these unique neuro-ophthalmic visual phenomena occur while in space which remain poorly understood by nonastronauts. There are various risks to the neuro-ophthalmic system in space including spaceflight-associated neuro-ocular syndrome and galactic cosmic radiation, and thus, further understanding what astronauts are experiencing is of critical importance. In this study, we employ artificial intelligence (AI) text-to-image AI frameworks to descriptions of visual phenomena experienced during spaceflight to further understand phosphenes and oscillopsia in space motion sickness. Building upon this technology may help researchers and clinicians to further understand how the spaceflight environment impacts the neuro-ophthalmic system.
Lacrimal gland cavernous hemangioma masquerading pleomorphic adenoma
Authors: Abusleme Eugenia I. , Arraño Leonardo , Bustos Juan Carlos , Bergeron Sabrina , Zoroquiain Pablo 
Published: December 2023

Abstract
A 62-year-old female patient consulted for a slowly progressive, painless, upper eyelid mass that has been present for 9 years. At examination, a nodular tumor in the orbital lobe of the lacrimal gland was observed. Computed tomography scan demonstrates a 15 mm, predominantly solid, well-demarcated lesion. The working diagnosis was suggestive of a pleomorphic adenoma. The mass was removed by anterior orbitotomy and the excisional biopsy revealed an intralacrimal gland cavernous hemangioma. Glucose transporter type 1 (GLUT1) immunohistochemistry was negative, confirming the hamartomatous nature of this vascular lesion. This case highlights the importance of considering vascular lesions in the differential diagnosis of lacrimal gland tumors as these tumors may need different management. In this case, GLUT1-negative immunohistochemistry was a helpful marker to differentiate a malformation from a neoplastic process.
Orbital mucosa-associated lymphoid tissue lymphoma
Authors: Teles Lucas Pinheiro Machado , Lima Júlia Cristina De Oliveira , Schmidt Luiz Paulo Bastos , Andrade Eric Pinheiro De 
Published: December 2023

Abstract
Orbital lymphomas are rare conditions, and most non-Hodgkin’s lymphomas of the orbit are extranodal lymphomas of B cells of the marginal zone of the mucosa-associated lymphoid tissue type (MALT). In this report, we describe a case of MALT-type marginal zone B lymphoma in the orbital region. A female patient, 45 years old, searched for ophthalmological care, complaining, for 15 years, of low visual acuity (VA) associated with nonpulsatile bilateral proptosis, VA of 20/30 in the right eye and 20/40 in the left eye, without other changes. Magnetic resonance imaging of the brain and orbits showed solid expansive lesions in both orbital spaces, with biopsy and immunohistochemical study of the left orbit, showing lymphoproliferative syndrome, favoring B lymphoma of the MALT-type marginal zone. Thus, in view of the nonspecific initial presentation of MALT lymphoma, the use of imaging tests, as well as microsurgical biopsy, is essential for early diagnosis and surgical planning and constitutes the gold standard for adequate diagnostic elucidation.
Manual versus automated gonioscopy: Pros and cons of semi-automated devices
Authors: Puerto Mayerly Lopez , Martinez Claudia , Criollo Eveling , Toquica Jeanneth , Gomez H. 
Published: December 2023

Abstract

Introduction:
Narrow anterior chamber angles (ACAs) are a risk factor for closed-angle glaucoma development, being highly prevalent in Latin-American population. Manual gonioscopy remains the gold standard for ACA evaluation; however, new technologies have emerged, mainly to improve measurement objectivity.

Purpose:
The purpose of the study was to estimate the agreement and reproducibility of ACA measurement between manual gonioscopy performed with Posner lens, versus semi-automated gonioscopy using a prototype of the GS-1 gonioscope (NIDEK Co., Ltd.).

Materials and Methods:
This was a prospective blinded diagnostic test and interobserver agreement study. Manual gonioscopy was performed by a glaucoma specialist (observer 1), and semi-automated gonioscopy was taken by trained technicians using the GS-1 device. Obtained images were saved and later analyzed by a second glaucoma specialist (observer 2). Univariate analysis and Cohen’s kappa coefficient were calculated to estimate agreement between the two methods for ACA amplitude measurement, graded according to the Shaffer’s classification system.

Results:
One thousand and five eyes of 503 patients were included in the study. The mean age was 50.1 years (range 18–93 years) and 64.5% of participants were women. Cohen’s kappa coefficient showed a moderate agreement among the two observers for ACA amplitude evaluation, which translated into a moderate reproducibility for gonioscopy performed with the GS-1 device compared with the gold standard (P < 0.05).

Conclusion:
Angle evaluation with semi-automated devices, such as the GS-1 gonioscope, can demonstrate concordant information compared with the gold standard, which remains being manual gonioscopy. Its main advantage is the possibility of storing photographic records for patient’s follow-up over time; however, these devices present certain limitations that make it necessary to carry out further studies.
Central serous chorioretinopathy: Chance or casualty?
Authors: Martínez-Ceballos María Alejandra , Daza-Irreño Laura Andrea , Rodríguez Francisco J. 
Published: December 2023

Abstract
We describe the clinical case of a man in the fifth decade of life with visual loss in his left eye without improvement since 2006, followed by a decreased visual acuity in 2017. The ophthalmic evaluation revealed bitemporal hemianopsia. A tumor in the pituitary gland was confirmed by a computed tomography scan and histopathological study. He was treated with systemic steroids and transsphenoidal resection. The patient improved his visual field, but his visual acuity remained decreased. Ophthalmological evaluation and imaging showed changes due to bilateral central serous chorioretinopathy (CSCR) with an acute process in the left eye during steroid systemic treatment. Reports suggest a possible association between the use of systemic corticosteroids and CSCR. Furthermore, the hormone-producing pituitary adenoma and retinal disease have been described. The ophthalmologist should consider the clinical backgrounds and risk factors associated with CSCR.
Good practices in simulation-based education in ophthalmology. A thematic series. An initiative of the Simulation Subcommittee of the Ophthalmology Foundation Part III: Curriculum development for simulation based education in ophthalmology training programs
Authors: Labuschagne Mathys , Thomsen Ann Sofia Skou , Lansingh Van , Grau Arturo , Clements John , Luciano Andreas Di , Musa Pablo , Ng Danny Siu-Chun , Filipe Helena Prior 
Published: December 2023

Abstract
Surgical training using the apprenticeship model of “see one, do one, teach one” originated with Halsted in the 19th century and has continued forward. However, it may not be the most optimal and effective way to train clinicians. Simulation-based training emerged in recent decades and follows a stepwise approach starting with basic skills training, moving on to procedural training culminating in team training in an authentic environment. Simulation is used for specific and specialized skills training, deliberate practice, mastery of learning, and rapid knowledge acquisition, creating a structured teaching and learning framework. Simulation-based education programs must be embedded into a curriculum and should not be an optional add-on. Several curriculum design models exist. In this review, the five-phase ADDIE approach was used to inform a prototype curriculum. ADDIE is the acronym for analyze, design, develop, implement, and evaluate. It is used for systematic instructional design where knowledge and performance gaps have been identified and where every step in the design is dictated by the learning outcomes. The ADDIE model is an iterative instructional design where the results of the formative evaluation of each phase may lead to any of the previous phases. The process validates the procedures and products related to the development of learner-centered learning encounters and adds credibility by analyzing and evaluating procedures and interrelatedness. Sufficient evidence that simulation training improves individual and team performance is available. It has a positive effect on self-confidence, knowledge, and operational performance. Further evidence proves that deliberate practice, procedural simulation, and debriefing can be transferred to operational performance in clinical settings and could result in safer and more efficient care for patients, health-care providers, and health systems.
Prospective Study of Clinical Characteristics and Visual Outcome in Vogt–Koyanagi–Harada Syndrome in a Tertiary Eye Hospital in South India
Authors: Balakrishnan Saranya , Arunachalasamy Chandrika , Ramalingam Uma 
Published: December 2023

Purpose:To describe the demographic pattern, clinical characteristics, treatment modalities, and visual outcome in Vogt–Koyanagi–Harada (VKH) disease patients observed at a tertiary eye care centre in South India.Methods:A prospective chart analysis of 38 patients with VKH disease.Results:Of the 38 VKH patients, 31 (81.6%) were female, the mean age was 39.8 years, and the median duration of symptoms was 10 days (range: 2 to 180 days). The most common ocular complaint was a defective vision (70 eyes or 92.1%). Extraocular manifestations were headache (13 patients or 34.2%) and tinnitus (4 patients or 10.5%). Twenty-four patients (63.2%) presented with bilateral panuveitis, and 12 patients (31.6%) had posterior uveitis. The most common posterior segment presentation included bilateral serous retinal detachment (100%), disc oedema (37 eyes or 48.7%), and vitritis (31 eyes or 40.8%). All patients (100%) were treated with oral and topical prednisolone, based on the ocular inflammation status, 9 patients (23.7%) required dexamethasone (intramuscular), 39 eyes (51.3%) required posterior subtenon triamcinolone, 16 patients (28.9%) required methotrexate, 1 (2.6%) required cyclophosphamide, 1 (2.6%) required azathioprine. At the final visit, the majority of the patients had statistically significant good visual outcomes.Conclusion:Prompt diagnosis and early initiation of treatment with systemic, local steroid and immunosuppressive therapy showed faster recovery with good visual outcome.
Challenges in Diagnosing and Treating Acutely Febrile Children with Suspected Malaria at Health Care Facilities in the Lake Mwanza Region of Tanzania
Authors: Koliopoulos Philip , Kayange Neema , Jensen Christian , Gröndahl Britta , Eichmann Jana , Daniel Tim , Huth Florian , Eckert Till , Klamm Nele , Follmann Marlene , Medina-Montaño Grey Carolina , Hokororo Adolfine , Pretsch Leah , Klüber Julia , Schmidt Christian , Züchner Antke , Addo Marylyn M. , Okamo Bernard , Mshana Stephen E. , Gehring Stephan 
Published: December 2023

ABSTRACT.
Acute febrile diseases transmitted by mosquitos are a diagnostic challenge for pediatricians working in sub-Saharan Africa. Misclassification due to the lack of rapid, reliable diagnostic tests leads to the overuse of antibiotics and antimalarials. Children presenting with acute fever and suspected of having malaria were examined at health care facilities in the Mwanza Region of Tanzania. The sensitivity and specificity of blood smear microscopy and malaria rapid diagnostic tests that targeted histidine-rich protein 2 and Plasmodium lactate dehydrogenase were compared with a multiplex reverse transcriptase-polymerase chain reaction (PCR)–ELISA. Six hundred ninety-eight children presented with acute fever and met the criteria for inclusion; 23% received antibiotics and 23% received antimalarials prior to admission. Subsequently, 20% were confirmed by PCR to have Plasmodium falciparum infection. Blood smear microscopy exhibited 33% sensitivity and 93% specificity. The malaria rapid test provided 87% sensitivity and 98% specificity in detecting acute malaria infections. Only 7% of malaria-negative children received antimalarials at Sengerema Designated District Hospital when treatment was guided by the results of rapid testing. In contrast, 75% of malaria-negative patients were treated with antimalarial drugs at health facilities that used blood smears as the standard diagnostic test. Misclassification and premedication of nonmalarial, febrile illnesses contribute to the emergence of antimalarial and antimicrobial resistance. The incorporation of malaria rapid diagnostic tests into the clinical routine translated into improved treatment and a significant reduction in antimalarial drug prescriptions.
Evaluasi Kebijakan Pemilihan Pesawat Terbang Polri dengan Menggunakan Analisis Technique of Order Preference by Similarity to Ideal Solution (Topsis)
Authors: Ariyanto Stefanus Timonora Wahyu 
Published: December 2023

Penelitian ini bertujuan melakukan melakukan evaluasi kebijakan dalam pemilihan alat utama Polri berupa pesawat terbang dengan menggunakan TOPSIS. kuantitatif dipilih sebagai methodological Choice-nya dengan menggunakan tujuh langkah pada metode Technique of Order Preference by Similarity to Ideal Solution (TOPSIS). Strategi Pengumpulan Data yang dilakukan adalah dengan telaah dokumen pada pesawat terbang yang akan dipilih serta menentukan kriteria yang akan digunakan. Teknik Analisis Datanya adalah dengan menggunakan pengolahan data di excel dengan menggunakan rumus yang terdapat pada tujuh langkah Technique of Order Preference by Similarity to Ideal Solution (TOPSIS) yang kemudian dimasukkan dalam formula setiap cell nya. Berdasarkan analisis dengan Technique of Order Preference by Similarity to Ideal Solution (TOPSIS), didapatkan hasil dimana berdasarkan perhitungan nilai preferensi (V), ditemukan bahwa preferensi nilai terbesar adalah 0,88. Dari hasil pemeringkatan dapat dilihat bahwa urutan pertama Boeing B737-900ER, peringkat kedua Boeing B737-800, peringkat ketiga Airbus A-320 dan peringkat keempat adalah Boeing 737-500. Hal ini menunjukkan bahwa jenis pesawat terbang yang paling tepat dipilih adalah jenis Boeing B7373-900ER