bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimente zum Primärprozeß der Photosynthese
Authors: Witt H. T. 
Published: October 2023

AbstractBei Anregung der Photosynthese mit Blitzlicht wurden mit einer besonderen Apparatur kurzzeitige optische Absorptionsänderungen beobachtet. In Abhängigkeit von verschiedenen physikalischen und chemischen Parametern zeigen diese Absorptionsänderungen Eigenschaften, die auf einen unmittelbaren Zusammenhang mit dem Primärprozeß hinweisen. Mit dieser Methode ist es möglich, den Primärprozeß der Photosynthese getrennt vom Gesamtprozeß zu untersuchen.
Das Göttinger Integralprogramm
Authors: Preuss H. 
Published: October 2023

AbstractBei der Berechnung von Moleküleigenschaften nach der Quantenmechanik sind eine Reihe langwieriger Integrationen erforderlich, die die Rechnungen stark belasten. Es ist daher sehr wünschenswert, die Integrale schon tabelliert vorliegen zu haben. Dieses Ziel verfolgt das hiesige Integralprogramm mit besonderer Hilfe der elektronischen Rechenmaschinen G 1 und G 2. Zur Zeit sind die Tabellen aller Wechselwirkungsintegrale mit gleichen Abschirmzahlen in den verwendeten Slater‐Funktionen und die Einelektronen‐integrale bei verschiedener Abschirmzahl sowie eine Reihe von Hilfsfunktionen fertiggestellt. Alle Tabellen werden in einigen Bänden im Springer‐Verlag veröffentlicht.
Die Struktur der Einschlußverbindungen des Phenols
Authors: Stackelberg M. V. , Hoverath A. , Scheringer Ch. 
Published: October 2023

AbstractDie isomorphen Verbindungen des Phenols mit X, HCl, HBr, HJ, H2S, H2Se, SO2, CO2, COS, CS2, CH3Br, CH2Cl2, CH3CHF2, CH2CHF kristallisieren in der rhomboedrischen Raumgruppe C32i — R 3 mit den Gitter‐konstanten a = 12,05 Å, α = 86,0° bis 85,0° (letzteres bei länglichen Gastmolekeln: SO2, CO2). Die Zelle enthält 12 Phenolmolekeln und normalerweise 4 Gastmolekeln, bei sehr kleinen Gastmolekeln (HCl, HBr) mehr, bei großen (CS2) weniger.Je 6 Phenolmolekeln sind zu einem Ring verbunden, indem die Sauerstoffatome über Wasserstoffbrücken zu einem ebenen Sechseck verkettet sind. Die an den Sauerstoffatomen hängenden 6 Phenylreste sind aus der Sechseckebene abwechselnd nach oben und nach unten herausgeklappt. Je zwei solche Sechsringe liegen im Abstand von 5,6 Å parallel übereinander. Diese Zwölfergruppen besetzen die Ecken der Elementarzelle (Normale der Sauerstoffring‐Ebenen in [111]‐Richtung). Im Inneren dieser Zwölfergruppe befindet sich der Hohlraum I. Art, der von einer Gastmolekel besetzt wird. Die größeren, in 1/2 1/2 1/2 liegenden, nach [111] gestreckten Hohlräume II. Art werden von 3 (bis 4) Gastmolekeln besetzt. Große Molekeln (CS2) besetzen nur die Hohlräume II, wobei in I Luftmolekeln aufgenommen werden können.Es handelt sich um ausgesprochene Käfigverbindungen. Die Struktur ist der der Hydrochinon‐Einschluß‐verbindungen analog.
Untersuchungen über das H+‐Ionengrenzstromgebiet
Authors: Breiter M. 
Published: October 2023

AbstractDas H+‐Ionengrenzstromgebiet wurde mittels stationärer potentiostatischer Stromspannungskurven und mittels kathodischer Einschaltvorgänge in stark verdünnten schwefelsauren Lösungen mit Fremdsalzüberschuß und ohne Fremdsalzzusatz an anodisch vorbehandelten glatten Pt‐Elektroden untersucht. Die in schwach schwefelsauren Lösungen mit Fremdsalzüberschuß bei H2‐Bespülung aufgenommenen kathodischen und anodischen Stromspannungskurven stimmen gut mit den unter der Voraussetzung berechneten Kurven überein, daß die Diffusion der H+‐Ionen und der H2‐Moleküle geschwindigkeitsbestimmend ist. Aus den Bezugsspannung‐Zeit‐Kurven kathodischer galvanostatischer Einschaltvorgänge von der Ruhespannung U = 0 aus wird die Übergangszeit τH+, innerhalb der die H+‐Ionenkonzentration an der Elektrodenoberfläche auf annähernd den Wert der H+‐Ionenkonzentration des neutralen Wassers absinkt, in Abhängigkeit von der kathodischen Stromdichte ik in schwach schwefelsauren Lösungen verschiedener H+‐Ionenkonzentration mit Fremdsalzüberschuß und ohne Fremdsalzzusatz ermittelt. Aus dem experimentellen Befund ik√rdτH+ = const für Lösungen mit Fremdsalzüberschuß und ohne Fremdsalzzusatz läßt sich schließen, daß die der H+‐Ionenabscheidung vorgelagerte Dissoziation von Wassermolekülen in H+‐Ionen und OH−‐Ionen in den untersuchten Lösungen praktisch ungehemmt abläuft. Der Einfluß des sich in Lösungen ohne Fremdsalzzusatz innerhalb der Diffusionsschicht ausbildenden elektrischen Potentialabfalls auf die Übergangszeiten τH+ wird diskutiert. Die Bezugsspannung‐Zeit‐Kurven anodischer galvanostatischer Einschaltvorgänge ergeben, daß die Belegung der Elektrodenoberfläche mit adsorbierten H‐Atomen an aktiven Pt‐Elektroden in schwach schwefelsauren Lösungen in ähnlicher Weise mit wachsender Bezugsspannung von U = 0 aus abnimmt wie in konzentrierteren Lösungen. Aus den anodischen Bezugsspannung‐Zeit‐Kurven in Lösungen mit Fremdsalzüberschuß läßt sich, wie ein Vergleich mit den unter der Annahme reiner Konzentrationsüberspannung berechneten Bezugsspannung‐Zeit‐Kurven zeigt, auf eine geringe Ionisierungshemmung der adsorbierten H‐Atome in H+‐Ionen schließen. Trotz der relativ geringen H+‐Ionenkonzentration in den verwendeten schwach schwefelsauren Lösungen ist der Einfluß der Durchtrittsreaktionen auf die Geschwindigkeit der kathodischen H+‐Ionenabscheidung bzw. der anodischen H2‐Auflösung an aktiven Pt‐Elektroden vernachlässigbar gegen den Einfluß der Transportvorgänge.
Die Geschwindigkeit der Oxydation (Korrosion) des Titans in geschmolzenem Salz und die Zusammensetzung der Oxydationsprodukte
Authors: Straumanis M. E. , Chiou Ch. 
Published: October 2023

AbstractWird metallisches Titan unter geschmolzenem NaCl in Gegenwart von Luft erhitzt, so oxydiert sich das Metall sehr schnell. Der Sauerstoff diffundiert hierbei durch die flüssige Salzschmelze zum Metall, wo er sich löst. Sobald die Oberflächenschicht eine Sauerstoff konzentration von etwa 6,2 Gew.‐%, der Zusammen‐setzung von TiO0.2 entsprechend, erreicht hat, bröckelt die Schicht vom Metall und wird im geschmolzenen Salz dispergiert. Diese TiOx‐Partikeln sind besonders aktiv, indem sie sich auf den Wänden des Tiegels oder auf manche, in die Schmelze getauchten Metalle in Form einer zusammenhängenden Ti‐Schicht abscheiden. Das Losbrechen der TiOx‐Oberflächenschicht vom kompakten Titan verursacht die schwere Korrosion des letzteren. Die Gewichtsverluste sind lineare Funktionen der Zeit und Temperatur und die Korrosions‐geschwindigkeiten betragen 0,00607 bei 880°, 0,0104 bei 950° und 0,0136 g h−1 cm−2 bei 1000 °C. Die niedrige Aktivierungswärme nach Arrhenius (19,140 cal mol−1, berechnet aus den Geschwindigkeiten) erklärt die Leichtigkeit des Oxydationsprozesses. Allein, die Reaktion könnte auch von nur scheinbarer nullter Ordnung sein.
Beobachtungen bei der Diffusion im System Gold‐Silber
Authors: Ruth V. 
Published: October 2023

AbstractNach einer kontinuierlichen Messung der Kirkendall‐Wanderung im System Gold‐Silber, die Karger mit einer Stabwaage durchführte, erfolgt die Verschiebung der markierten Schweißebene unstetig. Dieser Sachverhalt läßt vermuten, daß an dem Kirkendall‐Effekt die Verlagerung größerer Kristallbereiche beteiligt ist. An Hand der vorliegenden Beobachtungen einer Anzahl von Oberflächeneffekten, die bei der Metalldiffusion im System Gold‐Silber auftreten, konnte diese Vermutung erhärtet werden.Die Wulst‐ und Talzone in der Umgebung der Schweißnaht wurde in Abhängigkeit von der Glühdauer und ‐temperatur gemessen. Einige Oberflächenerscheinungen wurden mikrophotographisch untersucht: Die Ausbildung von kristallin geformten Löchern und von „Kanälchen”︁ auf der Seite der silberreicheren Legierung und auf der Seite der goldreicheren Legierung die Entstehung von Rissen längs der Korngrenzen und eine der Lochbildung analoge Erscheinung des Kristallwachstums. Ferner konnte in der Diffusionszone eine ausgeprägte Riffelbildung und eine Erhöhung der Sintergeschwindigkeit festgestellt werden.
Undescended superior parathyroid: A case report
Authors: Sina Elliott M. , Han Chihun J. , Cottrill Elizabeth E. 
Published: October 2023

AbstractAberrant migration of parathyroid glands from their embryologic origin may result in undescended parathyroid glands. We present a case of an ectopic parathyroid adenoma at the level of the pyriform sinus. A 41‐year‐old female was evaluated for primary hyperparathyroidism. Following non‐localizing ultrasound and planar sestamibi imaging, the patient underwent SPECT/CT and 4‐D computed tomography demonstrating evidence of an ectopic parathyroid adenoma. The surgical approach was modified based on the location. Following extirpation, PTH fell from 80 to 16 pg/mL, and the 15‐min post‐excision level remained stable at 14pg/mL, indicating a biochemical cure. While rare, undescended parathyroid adenoma should be considered when preoperative imaging fails to identify a target adenoma or after unsuccessful surgery. The combined use of 99m Tc‐MBI or 4D CT and other anatomical scans may improve diagnostic accuracy. Due to the potential need to perform a second incision to conduct a four‐gland exploration, preoperative patient discussion regarding surgical risks may differ from that of a standard parathyroidectomy.
Listeria meningitis diagnosed by blood culture with fever, neurological symptoms, and no meningeal irritation signs
Authors: Tago Masaki , Hirata Risa , Hirakawa Yuka , Makio Seijiro , Oishi Toru , Nakamura Masahiko , Yamashita Shun , Tokushima Yoshinori , Tokushima Midori , Katsuki Naoko E. , Aihara Hidetoshi , Fujiwara Motoshi 
Published: October 2023

Key Clinical MessageListeria can cause neurological symptoms in immunocompromised and older patients. Additionally, it is impossible to rule out meningitis by the absence of typical meningeal irritation signs. Therefore, patients with fever and neurological impairments should be rapidly examined for blood and cerebrospinal fluid cultures to rule out Listeria meningitis.AbstractA woman in her 90s developed fever, dysarthria, and transient disturbance of consciousness. Physical examination revealed no meningeal irritation signs. Listeria monocytogenes were detected in her blood culture the following day. Because of an increased number of cells in cerebrospinal fluid, she was diagnosed with Listeria meningitis.
Rapidly and successful improvement of nail psoriasis with risankizumab
Authors: Orsini Diego , Pacifico Alessia , Iacovelli Paolo , Frascione Pasquale , De Simone Paola , Assorgi Chiara , Pigliacelli Flavia 
Published: October 2023

Key Clinical MessageThis clinical case demonstrates quick resolution of nail psoriasis in a patient treated with risankizumab, highlighting the role of IL‐23 in the pathogenesis of nail psoriasis.
A life‐threatening presentation of postgastrectomy exocrine pancreatic insufficiency: A case report
Authors: Rahimipour Anaraki Shiva , Gholizadeh Mesgarha Milad , Bahadorizadeh Leyla , Hassanzadeh Morteza 
Published: October 2023

Key Clinical MessagePhysicians must be alert for the exocrine pancreatic insufficiency diagnosis through the follow‐up of postgastrectomy patients, regardless the severity and lag time. Urgent albumin and pancreatic enzyme replacement should be considered when diagnosed.AbstractIt is documented that exocrine pancreatic insufficiency (EPI) can develop after gastrectomy. Steatorrhea, malnutrition, and weight loss are common symptoms of the disease; however, it is usually mild to moderate postgastrectomy. This article reports a case of EPI manifested by hypoalbuminemia leading to dyspnea and anasarca, which are not typical symptoms of postgastrectomy EPI. A 61‐year‐old man with a history of gastric adenocarcinoma treated by total gastrectomy and chemoradiotherapy was admitted to the hospital with dyspnea and anasarca. Despite being diagnosed as a case of malignancy recurrence in another hospital, based on the symptoms described, no evidence of malignancy was found. His ascites and pleural effusion were determined to be caused by hypoalbuminemia. In addition, he claimed steatorrhea, and his stool elastase was lower than expected. EPI was diagnosed based on his medical history, paraclinical tests, and examinations. He remained asymptomatic for 1 year after being treated with albumin and pancreatic enzymes. Postgastrectomy EPI may be severe enough to cause steatorrhea or hypoalbuminemia. Hence, regardless of the severity of the presentation, physicians must be alert for this diagnosis throughout the follow‐up of patients with a history of gastrectomy. Urgent albumin and pancreatic enzyme replacement should be considered when diagnosed.
Impact of N, P, and K rates on stockpiled tall fescue in claypan soils
Authors: Yasuoka Junior Issamu , Pedreira Bruno C. , Helwig Dale , Farney Jaymelynn , Sassenrath Gretchen 
Published: October 2023

AbstractStockpiled tall fescue [Lolium arundinaceum (Schreb.) Darbysh.] is an alternative to extend the grazing season and reduce feeding costs during the winter. In addition, adequate fertility management with N, P, and K nutrients can improve forage production. Our objective was to evaluate the impact of N, P, and K fertilization (from 0 to 120 lb/a, 0 and 50 lb/a, and 0 and 30 lb/a, respectively) on forage accumulation (FA) and nutritive value in stockpiled tall fescue in claypan soils. The study was carried out in Columbus, KS, on established ‘Kentucky 31’ tall fescue pastures in the fall of 2019 and 2021 (two years). The treatments were one unfertilized control and fertilization with six combinations of nitrogen (0, 40, 60, 80, and 120 lb/a), phosphorus (0 and 50 lb/a), and potassium (0 and 30 lb/a) rates. Forage accumulation was greater in the treatments with at least 60 lb N/a compared with the unfertilized control (1,235 vs. 570 lb DM/a). However, the greatest crude protein content (CP; 13%) and crude protein accumulation (CPA; 163 lb CP/a) were produced when 120 lb N/a was applied. Nitrogen fertilization also resulted in greater total digestible nutrients, net energy gain, net energy maintenance, and lower acid detergent fiber. Phosphorus and potassium had little effect on the measured responses. Nitrogen fertilization can be an alternative to increase stockpiled tall fescue FA and nutritive value, reducing the need for energy and protein supplementation of livestock during the winter.
Pharmacokinetics and Drug–Drug Interaction of Allisartan Isoproxil and Indapamide Sustained‐Release Formulation
Authors: Yi Wu , Lin Sisi , Hao Rui , Shao Yiming , Wang Yannan , Yu Jin , Fang Lu , Zhu Jingjing , Wang Aiwei , Wu Yanfang , Huang Hua , Deng Chongyang , Sun Jingchao , Zhao Hongcan , Wang Ying , Tong Xiangming 
Published: October 2023

AbstractAllisartan isoproxil (AI) is an angiotensin II type 1 receptor blocker and be converted into the active substance EXP3174 in vivo. We evaluated the drug–drug interactions of AI and an indapamide sustained‐release (Ind SR) preparation, as well as the pharmacokinetic characteristics and safety of AI and Ind SR in healthy subjects. The trial was set up in 6 sequences and 3 cycles, and each cycle contained a 7‐day washout period. Subjects received 3 different trial drugs (A, AI; B, Ind SR; C, AI + Ind SR) during 3 different cycles. Twenty‐four subjects were enrolled in the clinical trial. Of these, 22 completed the study, 2 subjects dropped out due to adverse events (AEs). For subjects given AI alone or combined with Ind SR, the pharmacogenetic parameters Cmax and the geometric mean ratio of steady state (combined/single) of EXP3174 was 130%. The geometric mean ratio of area under the concentration–time curve over the dosing interval at steady state (combined/single use) was 144.5%. Therefore, the combination of Ind SR had an impact on the pharmacokinetics of AI. Then, the results indicated that the AI combination had no effect on the pharmacokinetics of Ind SR. Serious AEs did not occur. The AEs in this clinical trial were the same as those for AI and Ind SR. Combined administration resulted in 2 cases (2 subjects) of Grade 3 hypotension and 1 case of Grade 3 hypotension with AI alone. Considering that this trial included healthy volunteers, the risk of hypotension was expected to be manageable.
Thin diameter optical displacement sensor for grasping force sensing of surgical robot
Authors: Dong Jiayuan , Sato Kazutaka , Morizane Shuichi , Ueki Masaru , Takenaka Atsushi , Lee Sang‐Seok , Matsunaga Tadao 
Published: October 2023

AbstractThe purpose of this study is to realize a grasp force measurement of forceps for robotic surgery systems. Generally, surgical robot forceps is actuated by traction wire, and we have suggested a newly force sensing system by measuring the wire expansion utilizing micro displacement sensors. For measuring the elongation of the wire, the white‐light interference principle has been utilized on sensor system, and the sensor consists of a tip‐tilted optical fiber, a Fizeau interferometer and a sensor holder. In this report, displacement sensor has been successfully fabricated and mounted onto the wire to measure the elongation of the wire under tension and discussed the experimental results.
An exploratory study of brain temperature and choline abnormalities in temporal lobe epilepsy patients with depressive symptoms
Authors: Oates Mina , Sharma Ayushe A. , Nenert Rodolphe , Mueller Christina , Szaflarski Jerzy P. 
Published: October 2023

AbstractObjectiveEpilepsy and depression share neurobiological origins, and evidence suggests a possible bidirectional relationship that remains poorly understood. This exploratory, cross‐sectional study aimed to investigate this relationship by employing magnetic resonance spectroscopic imaging (MRSI) and thermometry (MRSI‐t) in patients with temporal lobe epilepsy (TLE) with comorbid depressive symptoms and control participants. This is the first study to combine MRSI and MRSI‐t to examine brain temperature and choline abnormalities in regions implicated in seizure onset and depression.MethodsTwenty‐six patients with TLE and 26 controls completed questionnaires and underwent imaging at 3T. Volumetric echo‐planar MRSI/MRSI‐t data were processed within the Metabolite Imaging and Data Analysis System (MIDAS). Choline (CHO) was quantified as a ratio over creatine (CRE; CHO/CRE). Brain temperature (TCRE) was calculated based on the chemical shift difference of H2O relative to CRE's stable location on the ppm spectrum. The Hospital Anxiety and Depression Scale measured anxiety and depressive symptoms. The Chalfont Seizure Severity Scale measured seizure severity in patients with TLE. Two sets of voxelwise independent sample t tests examined group differences in CHO/CRE and TCRE maps. Voxel‐based multimodal canonical correlation analysis (mCCA) linked both datasets to investigate if, how, and where CHO/CRE and TCRE abnormalities were correlated in TLE participants and controls.ResultsCompared to controls, patients with TLE reported more depressive symptoms (P = 0.04) and showed CHO/CRE and TCRE elevations in left temporal and bilateral frontal regions implicated in seizure onset and depressive disorders (pFWE < 0.05). For the TLE group, CHO/CRE levels in temporal and frontal cortices were associated with elevated TCRE in bilateral frontal and temporal gyri (r = 0.96), and decreased TCRE in bilateral fronto‐parietal regions (r = −0.95).SignificanceAbnormalities in TCRE and CHO/CRE were observed in seizure‐producing areas and in regions implicated in depression. These preliminary findings suggest that common metabolic changes may underlie TLE and depression. Our results suggest further investigations into the proposed bidirectional mechanisms underlying this relationship are warranted.
When molecular outsmarts morphology: Malignant ossifying fibromyxoid tumors masquerading as osteosarcomas, including a novel CREBZF::PHF1 fusion
Authors: Sharma Aarti E. , Dermawan Josephine K. , Sherrod Andy E. , Chopra Shefali , Maki Robert G. , Antonescu Cristina R. 
Published: October 2023

AbstractWe present two cases of malignant ossifying fibromyxoid tumor (OFMT) which eluded diagnosis due to compelling clinicopathologic mimicry, compounded by similarly elusive underlying molecular drivers. The first is of a clavicle mass in a 69 year‐old female, which histologically showed an infiltrative nested and trabeculated proliferation of monomorphic cells giving rise to scattered spicules of immature woven bone. Excepting SATB2 positivity, the lesion showed an inconclusive immunoprofile which along with negative PHF1 FISH led to an initial diagnosis of high‐grade osteosarcoma. Next generation sequencing (NGS) revealed a particularly rare CREBBP::BCORL1 fusion. The second illustrates the peculiar presentation of a dural‐based mass in a 52 year‐old female who presented with neurologic dyscrasias. Sections showed a sheeted monotonous proliferation of ovoid to spindle cells, but in contrast to Case #1, the tumor contained an exuberance of reticular osteoid and woven bone deposition mimicking malignant osteogenic differentiation. NGS showed a novel CREBZF::PHF1 fusion. Both tumors recurred locally less than 1 year post‐operatively. As such we reiterate that careful morphologic examination is axiomatic to any diagnosis in our discipline, but this paradigm must shift to recognize that molecular diagnostics can provide closure where traditional tools have notable limitations.
Estimation of 10‐year cardiovascular risk among adult population in western Nepal using nonlaboratory‐based WHO/ISH chart, 2023: A cross‐sectional study
Authors: Sitaula Deekshanta , Dhakal Aarati , Mandal Sujit K. , Bhattarai Nisha , Silwal Amisha , Adhikari Pradeep , Gupta Shikha R. , Khatri Dhan , Lageju Nimesh , Guragain Bhimsagar 
Published: October 2023

AbstractBackground and AimsNoncommunicable diseases have emerged as a major cause of morbidity and mortality worldwide among which the majority of the deaths are caused by cardiovascular diseases. Estimating the risk of cardiovascular diseases helps eliminate the risk factors and prevent developing cardiovascular diseases in the future. The World Health Organization in association with the International Society of Hypertension has developed risk charts for the estimation of 10‐year risk for cardiovascular diseases. This study aimed to estimate 10‐year cardiovascular risk in the Nepalese population using nonlaboratory‐based charts.MethodsA hospital‐based cross‐sectional study was conducted among 314 adults aged 40–74 years visiting the outpatient departments of Shishuwa Hospital in western Nepal. Systematic random sampling was used to select the participants. Questionnaire‐guided short interviews, physical examination, and anthropometric measurements were done. The χ2 test was used to test the significance and a p < 0.05 was considered statistically significant.ResultsAs per the risk estimation charts, high cardiovascular risk (20%–30%) was seen in 6.1% of total participants and moderate cardiovascular risk (10%–20%) was found in 29% of participants. The moderate–high risk was significantly higher among male participants compared to females (p < 0.01). Of all the participants, 22.0% were current smokers, 17.2% were alcohol users, 61.1% were hypertensive, and 35.7% were diabetics. Smoking tobacco, alcohol use, and hypertension were significantly more prevalent among the male participants. (p < 0.01) Adults in the 50–59 years age group had a significantly high prevalence of hypertension (p < 0.01), diabetes (p = 0.02), and alcohol abuse (p = 0.01).ConclusionThis study shows high cardiovascular risk among adult population in western Nepal. The 10‐year cardiovascular risk score and risk factors were significantly higher among males than females. There seems to be a prompt necessity of health promotion interventions to reduce cardiovascular risk factors and prevent the burden of cardiovascular diseases in Nepal.