bluuebunny/crossref_metadata_2025_split huggingface dataset:
Analysis of Leverage, Profitability and Interest Rate Ratio on Company Value With Size as an Intervening Variable
Authors: Ibnussoim Mohamad , Suyanto Suyanto 
Published: December 2023

The Indonesia Stock Exchange (IDX) is a place for transactions of shares of companies that have met the requirements. The incident of the spread of Covid-19 has an impact on stock market instability which also has an impact on company value. Investors are cautious in investing in the IDX including considering the value of the company. According to a number of studies, firm value (PBV) is influenced by leverage (DER), profitability (ROE), interest rates (BI Rate), and company size (SIZE) but inconsistently (positively or negatively). There are other studies that show an inconsistent relationship between DER, ROE, BI Rate and SIZE. Therefore, it is necessary to analyze DER, ROE, and BI Rate on PBV with SIZE as an intervening variable. The research was conducted on companies listed in LQ45 for the 2019-2022 Period using purposive sampling method and based on their annual financial statements. Other data is obtained from the Central Bureau of Statistics, and Yahoo Finance. Data processing using SmartPLS with the PLS-SEM method with a 95% confidence level reinforced by the Sobel Test. The results of the study are based on direct influence, namely: 1) Leverage (DER) has a significant positive effect on firm value (PBV), 2) Profitability (ROE) has no effect on firm value (PBV), 3) Interest Rate (BI Rate) has no effect on firm value (PBV), 4) Firm size (SIZE) has a significant negative effect on firm value (PBV), 5) Leverage (DER) has a significant positive effect on firm size (SIZE ), 6) Profitability (ROE) has no effect on firm size (SIZE), 7) Interest rate (BI Rate) has no effect on company size (SIZE). Based on the indirect effect, the results are: 1) Leverage (DER) has a significant negative effect on firm value (PBV) through firm size (SIZE), 2) Profitability (ROE) has no effect on firm value (PBV) through firm size (SIZE), and 3) Interest rates (BI Rate) have no effect on firm value (PBV) through company size (SIZE). Based on this research, companies need to be wise in managing debt in connection with the significant positive leverage (debt) on firm value. Likewise, with the effect of profitability (ROE) on firm value negatively although not significant, companies need to anticipate/be careful because in real conditions profitability should have a positive effect on firm value. This anomalous condition can occur during Covid-19 and therefore companies must be wiser in running their business effectively and efficiently in order to achieve high profitability and firm value.
Cloning and Characterization of Rep Gene of the Strain of Tomato Leaf Curl New Delhi Virus (G: Begomovirus, F: Geminiviridae) Infecting Ridge Gourd in Karnataka and in silico Analysis of Rep Protein
Authors: Ananya  , Nagesha N.  , Mahesha B.  
Published: December 2023

Ridge gourd [Luffa acutangula (Roxb.) L.,] is one of the important vegetable crop affected by various diseases particularly viral disease tomato leaf curl New Delhi virus (ToLCNDV). The ridge gourd plants with leaf curling and yellowing symptoms were collected and used in for the amplification of the of the Rep gene. Cloning, sequencing and bioinformatics analysis of the Rep gene was carried out. The results revealed the association of this virus isolate with the different host of Cucurbitaceae family. Pairwise identity derived implemented by BLAST identified that the replicator initiator protein gene (Rep) of the bipartite virus showed maximum 96.90% sequence identity to the corresponding Rep gene of ridge gourd tomato leaf curl New Delhi virus isolate RG3 in ridge gourd - complete genome from Madikari, Karnataka (accession no KT426905). This also showed 97.90% sequence similarities with tomato leaf curl New Delhi virus strain CH7 of Chrysanthemum. Phylogenetic dendrogram of the Rep gene depicted that it grouped with ToLCNDV of different Indian isolates of ridge gourd and with ToLCNDV of potato from Pakistan (LN908936), and with tomato from Bangladesh (KM383738.1) showing 93.12% and 92.94% sequence similarity respectively. This study provides association of the Rep gene infected ridge gourd pants with Cucurbitaceae family crops and other related crops. This will helps in carrying further research in the management of ToLCNDV diseases using different biotechnological applications.
Race, Population Affinity, and Mortality Risk during the Second Plague Pandemic in Fourteenth-Century London, England
Authors: Redfern Rebecca , DeWitte Sharon N. , Hefner Joseph T. , Kim Dorothy 
Published: December 2023

We investigate whether hazards of death from plague and physiological stress at a fourteenth-century plague cemetery (Royal Mint, London) differed between populations using N = 49 adults whose affiliation was established using macromorphoscopic traits. Compared to a nonplague cemetery (N = 96), there was a greater proportion of people of estimated African affiliation in the plague burials. Cox proportional hazards analysis revealed higher hazards of death from plague for those with estimated African affiliation. There were higher rates of linear enamel hypoplasia in those with estimated African affiliation, but this finding is not statistically significant. These results provide the first evidence that hazards of plague death were higher for people of estimated African affiliation compared to other affiliations, possibly because of existing inequalities, in addition to migration (free or forced) outcomes. These findings may reflect premodern structural racism’s devastating effects.
Investigamos si los riesgos de la muerte resultando de la peste y estrés fisiológico en un cementerio de la peste del siglo XIV (Royal Mint, Londres) son diferente entre poblaciones de adultos (N = 49) quienes afiliación estuvieron establecido utilizando rasgos macromorfoscópicos. En comparación con un cementerio no asociado con la peste (N = 96), había una proporción más grande de gente estimado tener afiliación africana en los entierros asociados con la peste. Análisis de riesgos proporcional de Cox indicaron que había un riesgo de muerte de la plaga más alto por individuos estimados tener afiliación africana. Había índices más grandes de hipoplasia de esmalte dental en individuos de afiliación africana, pero el nivel estadístico no fue significativo. Los resultados demuestran la primera evidencia que los riesgos de la muerte de la peste fueron más altos por gente de afiliación africana en comparación a otras afinidades, posiblemente como resultado de disparidades sociales en combinación con los efectos de migración (libre o forzada). Los resultados se pueden reflejar las consecuencias devastadoras del racismo estructural premoderno.
Impact of climate change on the dairy production in Fiji and the Pacific Island Countries and Territories: an insight for adaptation planning
Authors: Bundi Magiri Royford , Sagero Phillip , Danmaigoro Abubakar , Rashid Razia , Mocevakaca Wati , Singh Shivani , Okello Walter , A. Iji Paul 
Published: December 2023

Climate change affects weather patterns, leading to changes in average temperatures, increased frequency, variability, and intensity of extreme weather events, especially in the Pacific Island countries. Climate change poses the greatest threats to the sustainability of smallholder dairy farming in Fiji, with the farmers being highly vulnerable, yet their adaptive capacity is low. Additionally, the Pacific’s current and future sustainable livestock development will heavily depend on its ability to cope with climate variability and adapt to future climate changes. Available data indicate that there is high spatial and temporal variability of rainfall over Fiji Island with the mean annual rainfall ranging from 1600 to 3600 mm, with Rotuma station receiving the highest rainfall over Fiji Island. Rainfall in Fiji has shown an increasing and decreasing trend, where both minimum and maximum temperatures have shown a decreasing trend. This will have a great impact on the smallholder dairy farmers who consist of over 95% of the existing farmers. Using available information and drawing from other contexts or countries where data or information is unavailable, we provide an overview of dairy production in Fiji as a prototype to other Pacific Island Countries and Territories (PICTs), highlighting smallholder dairy systems in the Fijian dairy sector, challenges, and opportunities of the dairy sector in the PICTs. We conclude that climate change significantly impacts dairy production in Fiji and the Pacific.
Populist Foreign Policy of Venezuela and Hungary: Post-Westernism and Its Limitations
Authors: Lehoczki Bernadett 
Published: December 2023

The global rise of populism has fuelled academic interest in how populism impacts international relations. The article argues that the post-Western international order as a context and its perceived opportunities strongly guide the foreign policy conduct of populist leaders regardless of their ideological background or geographical situation. The cases examined are Venezuela under Hugo Chávez (1999–2013) and Hungary under Viktor Orbán since 2010 (excluding his first term between 1998 and 2002). The research questions are as follows: (1) how does post-Westernism manifest itself in Chávista and Orbánist foreign policy and (2) what limitations do or did they face in terms of their post-Western foreign policies? The analysis is structured along three interrelated thematic lines of foreign policy making: populists’ conflicts with traditional (Western) powers¸ populists’ search for new partnerships in the non-Western world, and empowerment of regional institutions. Finally, the limitations of post-Westernism are explained on a comparative basis to highlight the contradictory features of populist foreign policy making in terms of loud short-term successes and silent long-term challenges.
Editorial
Authors: Carrasco Ortega Omar Francisco 
Published: December 2023

Desde la primera edición del libro “Goodman&Gilman las bases farmacológicas de la terapéutica” publicada en 1941, se describía a la farmacología como una ciencia que estudia los orígenes, las propiedades físicas y químicas de los compuestos, explora las características farmacocinéticas, las acciones fisiológicas, e identifica los usos terapéuticos de los fármacos. Este extenso campo de estudio convierte a esta disciplina en un punto de referencia en el conocimiento médico.
El fin último de la práctica médica es aliviar al paciente, y si existe un alivio mediante la administración de medicamentos para alcanzar este fin, el médico debe entender cómo los fármacos llegan a su sitio de acción, debe dominar el conocimiento biológico de las membrabas celulares, el bioquímico de las características de los compuestos y su polaridad que les confiere atributos de liposolubilidad o hidrosolubilidad, el conocimiento anatómico que permite decidir la mejor vía de administración, el clínico que permite identificar el problema causante y de esta forma actuar para cumplir su deber profesional y humanístico. En este número de la Revista Farmacología se exploran diferentes ramas del conocimiento farmacológico, el desarrollo de fármacos, la descripción de características cinéticas y dinámicas de fármacos, análisis de la terapéutica y el análisis de datos farmacoepidemiológicos orientados en la farmacovigilancia; múltiples análisis farmacológicos que integran nuestro saber médico.
MEME KANSERI ALT TIPLERI ILE SERUM INFLAMATUAR BELIRTEÇLERI ARASINDAKI ILIŞKININ DEĞERLENDIRILMESI
Authors: TÜRKYILMAZ Zeliha , DEMİREL Tuğrul 
Published: December 2023

Amaç: Meme kanseri kadınlarda en sık görülen kanserdir. Meme kanserinin, luminal A, luminal B, cerbB2'den zengin tip, triple negatif moleküler subtipleri tanımlanmıştır. Bu çalışma moleküler subtipler ile enflamatuar belirteçler arasındaki ilişkiyi ortayı koymayı amaçlamıştır.
Gereç ve Yöntemler: Ocak 2019 ve Nisan 2023 tarihleri arasında opere edilen meme kanseri hastaları değerlendirmeye alındı. Hastaların demografik özellikleri, patoji değerlendirmeleri, moleküler alt tipleri ve labaratuvar verileri toplandı. Hemogramdan Nötrofil/Lenfosit oranı (NLR), Trombosit/Lenfosit oranı (PLR) ve Sistemik Enflamatuvar Yanıt İndeksi (SIRI) hesaplandı. Moleküler alt tipler ile enflamatuar belirteçler arasında ilişki istatistiksel olarak değerlendirildi.
Bulgular: Çalışmaya dahil edilen hastaların ortanca yaşı 56 idi. Hastaların %82,8'inde östrojen reseptörü (ER+), %61,3'ünde progesteron reseptörü (PR+) pozitif çıktı. En yaygın moleküler alt tip lümen A idi. Ki67 kesme değeri 14 olduğunda ER durumu arasında istatistiksel olarak anlamlı bir ilişki bulundu (p=0,047). Ki67 cut-off değeri 20 olarak alındığında hem ER ile (p=0,002), hem de PR ile istatistiksel olarak anlamlı ilişki (p=0,025) gözlendi. NLR ve PLR'nin ortanca değerleri sırasıyla 1,9 (aralık, 0,7:21,3) ve 123 (aralık, 53,3:252) idi.
Sonuç: Meme kanseri alt tipleri ile inflamatuar belirteçler arasında anlamlı bir ilişki bulamadık. Ancak cerbB2 ile PLR ve SIRI arasında istatistiksel olarak anlamlı fark gösterme eğilimi dikkat çekiciydi (sırasıyla p=0.08, p=0.057).
Az éghajlatváltozás várható hatásának integrált, modell alapú becslése a Felső-Tisza vízjárására, a bizonytalanság számszerűsítésével
Authors: Kis Anna , Pongrácz Rita , Bartholy Judit , Szabó János Adolf 
Published: December 2023

Tanulmányunkban a Felső-Tisza vidékére a klímaváltozásból eredő felszíni lefolyás várható megváltozását célzó becsléseink eredményeit foglaljuk össze, amelyeket szekvenciálisan végrehajtott többmodelles szimulációk alkalmazásával nyertünk. Az elemzés meteorológiai adatait a historikus időszakra a CARPATCLIM adatbázis, a jövőre pedig a RegCM4 regionális klímamodell szolgáltatta. Elemzési koncepciónknak megfelelően első lépésként a tény és a szimulált meteorológiai változók belső statisztikus variabilitásának számszerűsítésére egy Monte-Carlo ciklusba ágyazott időjárás-generátort (a DIWA-SDSWG-t) alkalmaztunk, amely képes előállítani reális, azonos valószínűségű, független szintetikus meteorológiai idősorokat. Majd ezen szintetikus adatokkal – mint felső peremfeltétellel – hajtottuk meg a fizikai alapú, térben és paramétereiben is osztott DIWA hidrológiai modellt, amely ezáltal megadta az adott meteorológiai szekvenciák hidrológiai válaszait, melyekből előállíthatóvá váltak a becslési bizonytalanság statisztikai jellemzői is. Eredményeink szerint a XXI. század során a napi középvízhozamok csökkenése várható a Felső-Tisza tiszabecsi szelvényében az évi átlagokat tekintve. A nyári hónapok lefolyásának jelentős csökkenése valószínűsíthető (különösen júliusban és augusztusban), míg januárra és februárra egy kisebb mértékű növekedésre számíthatunk. A harmadfokú árvízvédelmi készültségi szintet meghaladó esetek száma várhatóan szignifikánsan kevesebb lesz a XXI. század közepére és végére, azonban ezek időnként árvíztömegükben súlyosabbak lehetnek a jelenleg megszokottaknál. A kritikusan alacsony mederteltségek gyakoriságában drasztikus növekedésre számíthatunk a július és október közötti időszakban a jövőben, amely a századvégi időszakban jelentősebb.
Evaluation of the Emerging Small Scale Rural Aquaculture in Dara and Yirga Chefe Woredas of SNNPRS, Ethiopia
Authors: Debebe Samson , Gize Bazezew 
Published: December 2023

A survey on small scale fish farming practice was conducted in two woredas, namely Yirgachefe and Dara in the SNNPRS. The study intended to evaluate the state of the recently emerging fish farming practices in the woredas. Detail survey with regard to fish pond management, feeding, and stocking, identification of culture species, fish yield and marketing were conducted. It was found that on average, one pond was owned by fish farmers in both woredas. Statistically significant difference was observed with regard to pond size (P<0.05), where fish farmers in Dara owned larger ponds (176.4 m2) compared to farmers in Yirga chefe (130.5m2). All fish farmers under the study used earthen ponds to culture fish (P>0.05), and river is the principal source of water (74.6%) while spring water came second (25.4%). The majority of the ponds (82.7%) in both woredas (P>0.05) were stocked with Nile tilapia (Oreochromis niloticus) and only few of the farmers (17.3%) practice polyculture of Nile tilapia (Oreochromis niloticus) with African Catfish (Clarias gariepinus). In both areas (P>0.05) 91.3% of the farmers practiced pond fertilization while 8.7% of them did not. With regard to feeding, majority of the ponds (82.6%) were provided with supplementary feeds (P<0.05) and only small number ponds (17.4%) relied on natural foods alone. Depending on fry availability, farmers in both woredas stock their ponds once per year (P>0.05). The reported average weight of fish at harvest was 256.74g and the estimated annual fish yield was 4905.94kg/ha/yr in both woredas (P>0.05). Farmers in Yerga chefe exclusively utilized what they produced for home consumption purpose while farmers in Dara sold majority of their produce and utilized few of the harvest for home consumption. Lack of technological support, poor growth rate of culture fish species, shortage of fry and lack of quality fish feeds were identified as the major constraints of fish farming in the two woredas.
Análisis del estado anímico de estudiantes durante la pandemia
Authors: Yépez Sánchez Eliecer , Rodríguez Correal Patricia 
Published: December 2023

El artículo presenta los resultados obtenidos en una investigación que analizó el estado anímico en -tiempo real-, de un grupo de estudiantes de educación media, ubicados en edades entre 12 y 18 años, quienes recibieron educación virtual durante la pandemia por Covid-19.
Debido a que el gobierno nacional de la República de Colombia ordenó la cuarentena total por pandemia, las instituciones educativas del país fueron obligadas a adaptar todos sus Proyectos Educativos Institucionales de manera inmediata a los ambientes virtuales, sin tener en cuenta las condiciones sociales de la comunidad educativa.
Por otro lado, investigaciones desarrolladas por la psicología positiva, dan cuenta sobre cómo durante el proceso de enseñanza-aprendizaje adquieren especial relevancia los momentos positivos, los cuales son asociados al bienestar, a la comodidad y de manera análoga a la felicidad. Por estas razones, se consideró importante analizar el estado anímico de los estudiantes durante la educación virtual ofrecida en pandemia.
Esta investigación no indaga sobre las variables que inciden en un estado anímico, sólo pretende vincular el estado anímico con otras variables involucradas en los procesos educativos, para que puedan ser utilizadas de manera predictiva en planeaciones institucionales, especialmente en aquellos procesos mediados por TIC.
Obstacles to the use of electronic administration in primary schools within the Green Line from the point of view of school principals -Suggestions and solutions-
Authors: Naa'ila Haddad  
Published: December 2023

The current study aimed to explore the obstacles to the use of electronic management in primary schools within the Green Line, and to conclude solutions in order to reduce the obstacles to the use of electronic management, and to answer the questions of the study, the researcher used the integrated curriculum, through the use of the descriptive approach, in addition to the use of the qualitative approach, where the researcher developed a questionnaire, and the study population consisted of (627) and the study sample consisted of (120) school principals in primary schools, the interview sample were conducted With a sample of (15) principals, the results showed a moderate degree of obstacles to the use of electronic administration in primary schools within the Green Line. The study also came up with a set of proposals to reduce obstacles, including continuous training, infrastructure development, keeping up with modern developments, and updating electronic administrative systems. In light of the results of the study, the study recommended carrying out modernization operations for the infrastructure necessary for electronic management, as well as human development operations that include continuous training and development projects
Using Technological Tools in Palestinian Higher Education – Reality and Expectancy
Authors: Naem Ali Salah  , Muhammad Okkeh  
Published: December 2023

This study is entitled "Using Technological Tools in Palestinian Higher Education – Reality and Expectancy". It aims at identifying the reality, challenges, motives, incentives, and what is expected and hoped from the use of technological tools in higher education as perceived by the faculty members. To collect the data, the study used the qualitative approach, and used the in-depth interview and it was applied on an intentional sample of (16) faculty members at Palestine Ahliya University, with a percentage of (%10) of the study population. The results of the study revealed that there is a difference in the use of technological tools in teaching process based on the different programs and colleges, some of which delve deeper into the use of technological tools in teaching, while others use them up to the minimum. The university also provides the needed infrastructure and resources required to facilitate communication to serve the educational process. The results also showed that the most important challenges that face the faculty members are the lack of knowledge of some technological resources and not possessing the needed languages that facilitate communication with the external world. In addition, lack of acquaintance with foreign experts and scientists, lack of orienting learners to the effective usage of technology and lack of time and effort to view the scientific content on the internet are also to be considered of the most important challenges that face the faculty members. Furthermore, the most important incentives and motives are knowledge transfer through technological tools and the increase of scientific knowledge by searching the internet search engines to build the student's scientific personality. It is also expected and hoped that technological tools will be developed and used in teaching process; and the university to become dependent on the effective usage of those technological tools in teaching throughout signing agreements with international universities and experts.
The originality of the study is determined by the urgent need for modern technological tools in delivering scientific knowledge to university students. While many researchers have addressed e-learning in their studies, researchers in Palestinian society have not explored how to utilize modern technology tools