bluuebunny/crossref_metadata_2025_split huggingface dataset:
Demand for Statehood: The Case of Native Military Recruitment in World War II
Authors: Yi Joowon 
Published: September 2023

Abstract
This paper examines how the demand for independence appeared in the era of Decolonization. I argue that nationalist movements were more likely to emerge in places where the colonial authorities recruited the native population in World War II. The theory highlights the role of war veterans in creating the demand for independence and in facilitating it through organized collective action. Drawing on original World War II native recruitment data, an analysis of nationalist movements in sub-national units from 1945 to 1984 provides evidence consistent with the theory. The findings in this study help us better understand the rise of nationalist movements in the twentieth century and the political effects of military service.
The Power of Personal Archives in Witnessing, Teaching, and Visual Storytelling: The Armenian Memory Project
Authors: Masud Catherine , Marsoobian Armen T 
Published: September 2023

Abstract
The Armenian Memory Project (AMP) is a collaborative effort designed to harness the energy and resources of the University of Connecticut and the New England Armenian community for the goal of fostering greater understanding of the region’s Armenian cultural heritage and the impact human rights crimes had on the Armenian community. In 2019, students and faculty from the university worked with Armenian American institutions and individuals on an initial component of the AMP, employing digital media technology to tell the story of one immigrant Armenian family, the Dildilians. A unique course was created to produce a documentary film centring around this family’s experiences in Ottoman Turkey before, during, and after the Armenian Genocide. Designed and taught by a documentary filmmaker with support from a family archivist/historian, the course brought students together in a collaborative learning experience. By immersing themselves in the family’s extensive photograph archive, these students came to understand the important role that the past continues to play in the lives of present-day Armenians. Furthermore, by taking on the responsibility as storytellers of the Dildilian narrative, students developed a deeper identification with this distant history and, in a wider sense, an appreciation for the ethical value of memory in bearing witness to the past. This collaborative and participatory framework for teaching using archival collections can serve as a model for creating a transformative learning experience in the study of human rights, war, and genocide.
Relativistic binary-disc dynamics and the timing of OJ-287’s flares
Authors: Zwick Lorenz , Mayer Lucio 
Published: October 2023

ABSTRACT
We revisit the precessing black hole binary model, a candidate to explain the bizarre quasi-periodic optical flares in OJ-287’s light curve, from first principles. We deviate from existing work in three significant ways: (1) Including crucial aspects of relativistic dynamics related to the accretion disc’s gravitational moments. (2) Adopting a model-agnostic prescription for the disc’s density and scale height. (3) Using Markov chain Monte Carlo methods to recover reliable system parameters and uncertainties. We showcase our model’s predictive power by timing the 2019 Eddington flare within 40 h of the observed epoch, exclusively using data available prior to it. Additionally, we obtain a novel direct measurement of OJ-287’s disc mass and quadrupole moment exclusively from the optical flare timings. Our improved methodology can uncover previously unstated correlations in the parameter posteriors and patterns in the flare timing uncertainties. According to the model, the 26th optical flare is expected to occur on the 21st of August 2023 ± 32 d, shifted by approximately a year with respect to previous expectations.
Consenting Under Coercion: The Partial Validity Account
Authors: Bajaj Sameer , Tomlin Patrick 
Published: September 2023

Abstract
How is the validity of our consent, and others’ moral permission to act on our consent affected by coercion? Everyone agrees that in cases of two-party coercion—when X coerces Y to do something with or for X—the consent of the coerced is invalid, and the coercer is not permitted to act upon the consent they receive. But coercers and the recipients of consent are not always identical. Sometimes a victim, Y, agrees to do something to, with, or for Z because they are being coerced by X. Recently, several philosophers have argued that consent under third-party coercion can be fully valid. We argue that this view has troubling implications. We develop a novel view of consent in third-party coercion cases, which we call the partial validity account. The core idea is that, under severe coercion, Y’s consent is at most partially valid—it reduces the strength of, but does not completely dissolve, Z’s consent-sensitive duties. We argue that the partial validity account gets the right results in important cases and explains the moral factors at play better than alternative accounts.
Identification of microRNAs involved in ectomycorrhizal formation in Populus tomentosa
Authors: Tao Yuanxun , Li Chaofeng , Liu Ying , Xu Changzheng , Okabe Shin , Matsushita Norihisa , Lian Chunlan 
Published: September 2023

Abstract
The majority of woody plants are able to form ectomycorrhizal (ECM) symbioses with fungi. During symbiotic development, plants undergo a complex re-programming process involving a series of physiological and morphological changes. MicroRNAs (miRNAs) are important components of the regulatory network underlying symbiotic development. To elucidate the mechanisms of miRNAs and miRNA-mediated mRNA cleavage during symbiotic development, we conducted high-throughput sequencing of small RNAs and degradome tags from roots of Populus tomentosa inoculated with Cenococcum geophilum. This process led to the annotation of 51 differentially expressed miRNAs between non-mycorrhizal and mycorrhizal roots of P. tomentosa, including 13 novel miRNAs. Increased or decreased accumulation of several novel and conserved miRNAs in ECM roots, including miR162, miR164, miR319, miR396, miR397, miR398, novel-miR44 and novel-miR47, suggests essential roles for these miRNAs in ECM formation. The degradome analysis identified root transcripts as miRNA-mediated mRNA cleavage targets, which was confirmed using real-time quantitative PCR. Several of the identified miRNAs and corresponding targets are involved in arbuscular mycorrhizal symbioses. In summary, increased or decreased accumulation of specific miRNAs and miRNA-mediated cleavage of symbiosis-related genes indicate that miRNAs play important roles in the regulatory network underlying symbiotic development.
Perioperative Chemotherapy and Chemoradiotherapy for Patients With Resectable and Borderline Resectable Pancreatic Adenocarcinoma
Authors: Coveler Andrew L. , Pillarisetty Venu G. , Koh Wui-Jin , Zhen David B. , Park James O. , King Gentry G. , Sham Jonathan G. , Hannan Lindsay M. , Mann Gary N. , Baker Kelsey K. , Redman Mary W. , Swanson Paul E. , Chiorean E. Gabriela , Whiting Sam H. 
Published: October 2023

Objectives
Pancreatic ductal adenocarcinoma (PDA) is the third most common cause of cancer death in the United States. Most patients who undergo resection develop recurrence. Standard treatment confers a median overall survival (OS) of 24 months. Exposure to alternate regimens may prevent chemoresistance. This study evaluated multiagent perioperative therapy for potentially resectable PDA patients to improve OS.

Methods
A single center, phase 2, trial of patients with resectable or borderline resectable PDA. Patients received neoadjuvant therapy with induction chemotherapy (gemcitabine, docetaxel, capecitabine) for 3 cycles, chemoradiation (intensity-modulated radiation therapy with capecitabine and oxaliplatin) followed by surgery, and 2 months of adjuvant gemcitabine and oxaliplatin and 2 months of gemcitabine. The primary endpoint was OS. The secondary endpoint was recurrence-free survival (RFS).

Results
Thirty-two eligible patients were enrolled. Twenty-two patients underwent surgical resection. After a median follow-up of 56.8 months, mOS was 31.6 months (95% confidence interval [CI], 14.2–58.1) for all patients, 58.1 months (95% CI, 31.6 to NR) for those who completed surgery. The mRFS was 31.3 months (95% CI, 12.5 to NR).

Conclusions
Perioperative therapy with GTX, chemoradiotherapy, and adjuvant GemOx/Gem resulted in promising survival of 58 months for patients who underwent resection and may represent another treatment option for PDA.
Relating Therapy for Distressing Voices in the Context of Anorexia Nervosa
Authors: Pugh Matthew , Bibby-Jones Anna-Marie , Coyle-Stewart Annabel , Hayward Mark 
Published: October 2023

Abstract
Voice hearing experiences are commonly reported by patients with anorexia nervosa (AN) and are associated with negative outcomes. The “eating disorder voice” (EDV) can be understood within relational frameworks. Relating therapy (RT) has offered encouraging outcomes when targeted at voice hearing experiences transdiagnostically but has not been evaluated in the context of AN. This study aimed to offer a preliminary and mixed methods exploration of RT for the EDV. RT was delivered to three participants with a diagnosis of AN who were distressed by an EDV. Weight, negative impact of voices, and eating disorder cognitions were assessed at baseline, posttherapy and at brief follow-up. Participant experiences were explored through exit interviews. Therapy was completed by all participants. Weight gain was reported by two participants and maintained at brief follow-up. Positive changes were not reported on other measures. Qualitative data were suggestive of positive experiences that facilitated assertive responding.
Impact of Mental Health Legislation on Public Interest and Awareness of Common Mental Disorders
Authors: Alibudbud Rowalt 
Published: October 2023

Abstract
This study explored online public interest using search volumes for various mental disorders using an infodemiological design. Google Trends search volumes for schizophrenia, bipolar disorder, major depressive disorder, anxiety disorder, and substance abuse from January 2004 to December 2021 in the Philippines were described and compared. In addition, interrupted time series and mean comparisons were done to determine the impact of the Philippine Mental Health Act. Findings show that public interest was highest for major depressive disorder, followed by anxiety disorder, substance abuse, bipolar disorder, and schizophrenia. Among them, public interest in schizophrenia, major depressive disorder, bipolar disorder, and substance abuse improved following the Act's legislation. The uneven stigma of mental disorders and the incomplete implementation and unequal focus of Philippine mental health promotion programs can explain these findings. Thus, mental disorders with low public interest should be given attention in mental health awareness activities.
The social equity and the spatial accessibility of general hospitals in big Chinese cities: an exploration based on different income groups and transportation modes in Shenzhen
Authors: Xia Yuanxiang , Zhu Wenjian 
Published: October 2023

Abstract

Objectives:
The rational planning and allocation of hospitals significantly improve residents’ health and quality of life. However, the unequal allocation of medical resources remains a significant issue in large Chinese cities. This study investigated the disparities in access to health care among different social groups in Shenzhen and explored the discrepancy in equity and its influencing mechanisms.

Methods:
The population was divided into 5 social groups based on housing prices: high-income, middle-high income, middle-income, middle-low income, and low-income. The actual travel times of residential neighborhoods and general hospitals under both driving and public transportation were accessed through the application programming interface Amap, a mapping technology application. The accessibility of general hospitals was calculated by the Gaussian-based 2-step floating catchment area method. The Gini coefficient was used to further investigate the equity in medical facility services.

Results:
Accessibility to first and second-level hospitals was adequate for the high-income group. However, a significant spatial mismatch in the allocation of hospitals was identified for the middle-low income and low-income groups, especially those reliant on public transportation.

Conclusions:
This study reveals an inequitable allocation of hospitals, with driving accessibility generally superior to public transport accessibility in Shenzhen, and a significant spatial mismatch for middle-low income and low-income groups. This study suggests optimizing public transportation around hospitals and middle-low income or low-income neighborhoods through urban planning to improve the accessibility of public service facilities for middle-low income and low-income households, thereby promoting more health equity.
Can Whole-Body Magnetic Resonance Imaging Predict Relapse in Juvenile Idiopathic Arthritis? A Longitudinal Pilot Study
Authors: Bhalla Deeksha , Bagri Narendra , Jana Manisha , Upadhyay Ashish Datt 
Published: October 2023

Objective
To determine the utility of whole-body magnetic resonance imaging (WB MRI) to predict relapse in children with juvenile idiopathic arthritis (JIA) in clinical remission.

Methods
Consecutive patients with JIA who fulfilled the Wallace criteria for remission were recruited into this longitudinal pilot study and underwent WB MRI. A radiological score was devised, incorporating synovitis, bone marrow edema, sacroiliitis, enthesitis, and bone erosions. Two readers independently scored the MR data sets. The same score was calculated for both knee joints individually and correlated with outcome for that joint. Score-based models incorporating clinical and laboratory variables were generated. Logistic regression analysis was done to determine predictors for relapse. Receiver operating characteristic curve was drawn for significant variables.

Results
Twenty-two children (median age, 12 years; interquartile range, 9.5–14.25 years) were included in the final analysis. At 24 months' follow-up, 15 joints in 5 children relapsed; knee was the most common site. Seven knee joints had disease relapse. On univariate analysis, synovitis and total score on WB MRI were significant predictors of relapse at follow-up, with odds ratios of 9.46 (bias-corrected 95% confidence interval, 3.07–29.13) and 2.8 (bias-corrected 95% confidence interval, 1.23–6.39) respectively. Two models, which included a higher number of joints involved at presentation and abrupt drug withdrawal strategy as predictor variables, were also statistically significant (odds ratio, approximately 1.9). On multivariate analysis of the predictors variables in models where p < 0.6, it was found that only synovitis score and total score were near statistical significance (p = 0.06); no clinical or laboratory variables were significant. The areas under the receiver operating characteristic curve for relapse prediction were approximately 0.82, 0.87, 0.79, and 0.81 for synovitis score, total MRI score, and both models, respectively.

Conclusion
Synovitis on WB MRI is the strongest independent predictor for disease relapse in children with JIA in remission
Eating disorders in transgender and gender diverse people: characteristics, assessment, and management
Authors: Keski-Rahkonen Anna 
Published: October 2023

Purpose of reviewThis review summarizes recent research on eating disorders among gender minorities, transgender and gender diverse people. The focus is on research published in 2022 and the first half of 2023.Recent findingsUp to 1.2% of young people and 0.3–0.5% of adults identify as transgender, and 2.7–8.4% of young people and 0.3–4.5% of adults report some degree of gender diversity. About 20–50% of transgender and gender diverse people report engaging in disordered eating and >30% screen positive for eating disorder symptoms, and 2–12% have received an eating disorder diagnosis from a health professional. Many transgender and gender diverse people describe eating disorder symptoms as a way of coping with gender dysphoria. They also report high levels of mental and behavioral symptoms, particularly mood and anxiety disorders, suicidal thoughts and behaviors, trauma-related symptoms and disorders, alcohol and substance use, and autism. Gender minorities frequently experience discrimination, victimization, and violence, primarily sexual and physical violence. The minority stress model attributes mental health symptoms to these factors. Promising interventions based on the minority stress model have recently become available, but more research is needed on how to support transgender and gender diverse people with eating disorders. To manage eating disorders in this population, gender-affirming care should be combined with specialist eating disorder treatment.SummaryGender minorities are at high risk for eating disorders. Future studies should assess what is the most appropriate treatment for transgender and gender diverse people with eating disorders.
Effect of Baduanjin exercise of obstructive sleep apnea-hypopnea in chronic obstructive pulmonary disease: a study protocol for a randomized, single-blind, controlled trial
Authors: Zhang Xi , Cai Yi-hang , Ye Kang-Jie , Li Yu-Jin , Li Ji-Qiang , Zhang Zhong-De 
Published: September 2023

AbstractBackgroundBaduanjin is one of the traditional Chinese treatments for respiratory diseases. However, its effects on overlap syndrome (obstructive sleep apnea-hypopnea and chronic obstructive pulmonary disease) have not been rigorously tested. This study aims to evaluate the benefits and safety of Baduanjin treatment in chronic obstructive pulmonary disease (COPD) patients with obstructive sleep apnea-hypopnea (OSAH).MethodsCOPD patients with OSAH will be randomly allocated in a 1:1 ratio to Baduanjin group or control group. Both groups receive continuous positive airway pressure therapy and basic medication for 12 weeks. Baduanjin group will receive additional instructional Baduanjin exercises. The primary outcomes are BODE index. The secondary outcomes are polysomnogram, cardiopulmonary exercise test, Beck Depression Scale-II, and Saint George’s Respiratory Questionnaire.DiscussionThis trial will provide preliminary evidence about the efficacy and safety of Baduanjin exercise for COPD patients with OSAH. Baduanjin exercises may become an additional option for pulmonary rehabilitation of OSA-COPD overlap syndrome.Trial registrationClinicalTrials.gov, ID: NCT ChiCTR2200063171. Registered retrospectively on 1 June 2022.
The Physical Biology of Nucleolus Disassembly
Authors: Pham An T. , Mani Madhav , Wang Xiaozhong A. , Vafabakhsh Reza 
Published: September 2023

AbstractDuring cell division, precise and regulated distribution of cellular material between daughter cells is a critical step and is governed by complex biochemical and biophysical mechanisms. To achieve this, membraneless organelles and condensates often require complete disassembly during mitosis. The biophysical principles governing the disassembly of condensates remain poorly understood. Here, we used a physical biology approach to study how physical and material properties of the nucleolus, a prominent nuclear membraneless organelle in eukaryotic cells, change during mitosis and across different scales. We found that nucleolus disassembly proceeds continuously through two distinct phases with a slow and reversible preparatory phase followed by a rapid irreversible phase that was concurrent with the nuclear envelope breakdown. We measured microscopic properties of nucleolar material including effective diffusion rates and binding affinities as well as key macroscopic properties of surface tension and bending rigidity. By incorporating these measurements into the framework of critical phenomena, we found evidence that near mitosis surface tension displays a power-law behavior as a function of biochemically modulated interaction strength. This two-step disassembly mechanism, which maintains structural and functional stability of nucleolus while allowing for its rapid and efficient disassembly in response to cell cycle cues, may be a universal design principle for the disassembly of other biomolecular condensates.
Evolutionary patterns and heterogeneity of Dengue Virus serotypes in Pakistan
Authors: Mumtaz Zilwa , Saif Rashid , Yousaf Muhammad Zubair 
Published: September 2023

AbstractComprehensive and systematic examination of Dengue virus (DENV) evolution is essential in the context of Pakistan as the virus presents a significant public health challenge with the ability to adapt and evolve. To shed light on intricate evolutionary patterns of all four DENV serotypes, we analyzed complete genome sequences (n=43) and envelope (E) gene sequences (n=44) of all four DENV serotypes collected in Pakistan from 1994 to 2023 providing a holistic view of their genetic evolution. Our findings revealed that all four serotypes of DENV co-circulate in Pakistan with a close evolutionary relationship between DENV-1 and DENV-3. Genetically distinct serotypes DENV-2 and DENV-4 indicate that DENV–4 stands out as the most genetically different, while DENV-2 exhibits greater complexity due to the presence of multiple genotypes and the possibility of temporal fluctuations in genotype prevalence. Selective pressure analysis in Envelope (E) gene revealed heterogeneity among sequences (n=44) highlighting 46 codons in the genome experiencing selective pressure, characterized by a bias towards balancing selection indicating genetic stability of the virus. Furthermore, our study suggested an intriguing evolutionary shift of DENV-4 towards the DENV-2 clade, potentially influenced by antibodies with cross-reactivity to multiple serotypes providing a critical insight into the complex factors shaping DENV evolution and contributing to the emergence of new serotype.Author SummaryThe emergence of the fifth serotype of dengue virus heightened our interest in investigating its presence in Pakistan. In our quest to understand the evolving landscape of dengue in Pakistan, we conducted a comprehensive analysis, comparing whole genome sequences and E gene sequences. Notably, we focused on the E gene recognized as the most mutable component and a key determinant of dengue’s virulence. The phylogenetic analysis unveiled fascinating findings, demonstrating a strong genetic affinity between serotypes 1 and 3. Substantially signifying its implications for vaccine development and understanding of cross-immunity dynamics within serotypes. We delved into the genetic dynamics of dengue by subjecting the whole genome of DENV and E gene to neutrality tests. The outcomes of these tests unveiled a critical aspect of dengue virus evolution: the genome is not evolving neutrally. Instead, the E gene experiences selective pressure, indicating a bias towards balancing selection. The finding underscores the complex interplay of factors shaping the genetic diversity of dengue in Pakistan and provides valuable insights into the virus’s adaptive strategies.