bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparing COVID-19 severity in patients hospitalized for community-associated Delta, BA.1 and BA.4/5 variant infection
Authors: Sočan Maja , Mrzel Maja , Prosenc Katarina , Korva Miša , Avšič-Županc Tatjana , Poljak Mario , Lunar Maja M. , Zupanič Tina 
Published: February 2024

BackgroundDespite decreasing COVID-19 disease severity during the Omicron waves, a proportion of patients still require hospitalization and intensive care.ObjectiveTo compare demographic characteristics, comorbidities, vaccination status, and previous infections in patients hospitalized for community-associated COVID-19 (CAC) in predominantly Delta, Omicron BA.1 and BA.4/5 SARS-CoV-2 waves.MethodsData were extracted from three national databases—the National COVID-19 Database, National Vaccination Registry and National Registry of Hospitalizations.ResultsAmong the hospitalized CAC patients analyzed in this study, 5,512 were infected with Delta, 1,120 with Omicron BA.1, and 1,143 with the Omicron BA.4/5 variant. The age and sex structure changed from Delta to BA.4/5, with the proportion of women (9.5% increase), children and adolescents (10.4% increase), and octa- and nonagenarians increasing significantly (24.5% increase). Significantly more patients had comorbidities (measured by the Charlson Comorbidity Index), 30.3% in Delta and 43% in BA.4/5 period. The need for non-invasive ventilatory support (NiVS), ICU admission, mechanical ventilation (MV), and in-hospital mortality (IHM) decreased from Delta to Omicron BA.4/5 period for 12.6, 13.5, 11.5, and 6.3%, respectively. Multivariate analysis revealed significantly lower odds for ICU admission (OR 0.68, CI 0.54–0.84, p &lt; 0.001) and IHM (OR 0.74, CI 0.58–0.93, p = 0.011) during the Delta period in patients who had been fully vaccinated or boosted with a COVID-19 vaccine within the previous 6 months. In the BA.1 variant period, patients who had less than 6 months elapsed between the last vaccine dose and SARS-CoV-2 positivity had lower odds for MV (OR 0.38, CI 0.18-0.72, p = 0.005) and IHM (OR 0.56, CI 0.37- 0.83, p = 0.005), but not for NIVS or ICU admission.ConclusionThe likelihood of developing severe CAC in hospitalized patients was higher in those with the Delta and Omicron BA.1 variant compared to BA.4/5.
Medical errors, affected sites, and adverse consequences among patients in the orthopaedic department: Does age matter?
Authors: Liu Paicheng , Cheng Jianxin , Yang Yuxuan , Zhu Haipeng 
Published: February 2024

BackgroundOrthopaedics have become the focus of research on patient safety due to the high incidence of medical errors. Previous studies were based on all orthopaedic patients and rarely conducted empirical analyses from the perspective of age. This study aimed to fill the academic gap in the age variable by comparing medical errors, affected sites, and adverse consequences in orthopaedic patients.MethodsThis retrospective study included 329 litigation claims against orthopaedists using data from China Judgments Online. First, we performed computer crawling and screened 5,237 litigation documents using keywords, including medical errors. Second, 2,536 samples were retained through systematic random sampling, and 549 irrelevant cases were deleted after manual reading. Finally, three clinicians from different medical departments selected 329 incidents related to orthopaedics for further analysis, according to the description of the lawsuits. Three other professional orthopaedists evaluated the patients’ ages, affected sites of medical errors, and adverse consequences.ResultsThe greatest number of medical errors was observed in the joints (30.43%) for all orthopaedic patients. However, adult patients (aged 18–60 years) were most susceptible to errors in the extremities (30.42%). A higher rate of complications was associated with a higher rate of morbidity/mortality for the corresponding patients. Medical errors correlated with complications occurred in the following sites: joints (15.38%), extremities (12.50%), spine (16.95%), multiple sites (15.38%), and hands and feet (14.81%). In addition to surgical errors, over 10% of all orthopaedic patients experienced missed diagnoses. The incidence of insufficient adherence to informed consent obligations was 13.5% among adult patients and was much higher in paediatric and older adults patients. When orthopaedic patients suffered from medical technical errors, iatrogenic mortality/morbidity would decrease by 0.3% for one unit increase in age.ConclusionDividing patients into different ages demonstrated diverse results in terms of medical errors and affected sites. Negligence in diagnosis and examination can be fatal factors that endanger safety, and complications may cause morbidity/mortality. When patients suffered from technical errors, age is inversely proportional to mortality/morbidity. Special attention needs to be paid to technical errors in the younger older adults population (60–64 years old), which has inspired implications in promoting aging and public health.
Sustainability of shared economy in the agri-food, tourism, and hospitality industries
Authors: Alloh Karel , Abrham Josef , Sanova Petra , Čermák Michal , Petrzilka Slavibor , Schilla Filip 
Published: February 2024

IntroductionThis study aims to provide a systematic literature review on the sustainability of shared economy in the food, agricultural, and hospitality sectors. We assess relationships between the sharing economy and sustainability in the examined industries. Furthermore, we identify gaps in knowledge and recommend possible research directions for future studies.MethodsThis study provides a systematic literature review on sustainable sharing economy in the hospitality and agri-food sectors. We applied the Procedure for Systematic Reviews and Meta-Analyses (PRISMA). Based on the mentioned methodological procedure, we conducted a literature search through scientific databases Scopus and Web of Science. The research period is 2014–2023.ResultsUsing the Procedure for Systematic Reviews and Meta-Analyses (PRISMA), we extracted 2185 scientific articles from the Scopus and Web of Science databases published between 2014 and 2023. A total of 117 studies met the eligibility criteria. Based on the review, we identified the following frequently researched areas in the literature: sustainable housing sharing, urban and community sustainability, energy efficiency and carbon footprint, public sector regulation and sustainability, food sharing, exchanges and networks, food waste-reducing platforms, and food-based applications.ConclusionThe studies reviewed confirmed growing research interest in the sustainability of the shared economy in agri-food and hospitality. The number of studies in the Web of Science and Scopus databases has increased over the last decade. Our systematic review indicates that shared accommodation and food sharing are dominant topics in the literature. The sustainability of shared accommodation has been examined in previous studies, mainly concerning the impacts on cities and communities. In food sharing, we identified relevant linkages between food waste and sharing platforms.
Improving risk communication: a proof-of-concept randomised control trial assessing the impact of visual aids for neurosurgical consent
Authors: Chatzopoulou Despoina , Jalal Arif Hanafi Bin , Stoyanov Danail , Marcus Hani J. , Pandit Anand S. 
Published: February 2024

IntroductionInformed consent is a fundamental component in the work-up for surgical procedures. Statistical risk information pertaining to a procedure is by nature probabilistic and challenging to communicate, especially to those with poor numerical literacy. Visual aids and audio/video tools have previously been shown to improve patients' understanding of statistical information. In this study, we aimed to explore the impact of different methods of risk communication in healthy participants randomized to either undergo the consent process with visual aids or the standard consent process for lumbar puncture.Material and methodsHealthy individuals above 18 years old were eligible. The exclusion criteria were prior experience of the procedure or relevant medical knowledge, lack of capacity to consent, underlying cognitive impairment and hospitalised individuals. After randomisation, both groups received identical medical information about the procedure of a lumbar puncture in a hypothetical clinical scenario via different means of consent. The control group underwent the standard consent process in current clinical practice (Consent Form 1 without any illustrative examples), whereas the intervention group received additional anatomy diagrams, the Paling Palette and the Paling perspective scale. Anonymised questionnaires were received to evaluate their perception of the procedure and its associated risks.ResultsFifty-two individuals were eligible without statistically significant differences in age, sex, professional status and the familiarity of the procedure. Visual aids were noted to improve the confidence of participants to describe the risks by themselves (p = 0.009) and participants in the intervention group felt significantly less overwhelmed with medical information (p = 0.028). The enhanced consent process was found to be significantly more acceptable by participants (p = 0.03). There was a trend towards greater appropriateness (p = 0.06) and it appeared to have “good” usability (median SUS = 76.4), although this also did not reach statistical significance (p = 0.06)ConclusionVisual aids could be an appropriate alternative method for medical consent without being inferior regarding the understanding of the procedure, its risks and its benefits. Future studies could possibly compare or incorporate multiple interventions to determine the most effective tools in a larger scale of population including patients as well as healthy individuals.
Genetic and Phenotypic Characterization of Bacillus velezensis Strain BV379 for Human Probiotic Applications
Authors: Brutscher Laura M. , Gebrechristos Sebhat , Garvey Sean M. , Spears Jessica L. 
Published: February 2024

Bacterial spore-forming Bacillaceae species, including Bacillus subtilis and Heyndrickxia coagulans, are increasingly utilized for probiotic dietary supplementation. Bacillus velezensis is a Bacillus species that is frequently used as a direct-fed microbial in animal feed but less so as a probiotic for humans. The objective of this study was to characterize the suitability of the Bacillus velezensis strain BV379 for probiotic applications by (1) in silico screening for both adverse genetic elements and putatively beneficial traits, (2) in vitro evaluation of interactions with human intestinal epithelial cells, and (3) in vitro characterization of BV379 spore viability at various temperatures, pH, and in the presence of bile salt. In silico screening of the BV379 genome revealed few genes encoding Bacillaceae-associated toxins, virulence factors, and enzymes involved in the production of toxins. While BV379 encodes five antimicrobial resistance genes, minimum inhibitory concentration assays determined that BV379 is susceptible to all eight clinically relevant antibiotics tested. Preliminary cell culture experiments showed that BV379 lysates did not adversely impact human intestinal epithelial cell viability and monolayer permeability. It was also determined that BV379 spores can easily tolerate the harsh pH, bile salt, and microaerobic conditions typical of the GI tract. Altogether, the results presented herein support the safety and potential of Bacillus velezensis strain BV379 for use as an oral probiotic.
Synthesis, Characterization, and Catalytic Behaviors in Isoprene Polymerization of Pyridine–Oxazoline-Ligated Cobalt Complexes
Authors: Hao Xiuge , Liu Jin-Kui , Zhuo Weize , Zheng Jiajing , Hao Xin-Qi , Gong Jun-Fang , Jiang Hui , Song Mao-Ping 
Published: February 2024

A family of pyridine–oxazoline-ligated cobalt complexes L2CoCl2 3a–h were synthesized and characterized. Determined via single-crystal X-ray diffraction, complexes 3a and 3d, ligated by two ligands, displayed a distorted tetrahedral coordination of a cobalt center. The X-ray structure indicated the pyridine–oxazoline ligands acted as unusual mono-dentate ligands by coordinating only to Noxazoline. Upon activation with AlEt2Cl (diethylaluminum chloride), these cobalt complexes all exhibited high catalytic activity (up to 2.5 × 106 g·molCo−1·h−1), affording cis-1,4-co-3,4-polyisoprene with molecular weights of 4.4–176 kg mol−1 and a narrow Ð of 1.79–3.42, suggesting a single-site nature of the active sites. The structure of cobalt catalysts and reaction parameters, especially co-catalysts and the reaction temperature, all have significant influence on the polymerization activity but not on the microstructure of polyisoprene.
Using Photovoice to Explore the Lived Environment and Experience of Older Adults with Frailty on their Kidney Transplant Journey
Authors: Hladek Melissa deCardi , Wilson Deborah , Krasnansky Katie , McDaniel Kennedy , Shanbhag Meera , McAdams-DeMarco Mara , Crews Deidra C. , Brennan Daniel C. , Taylor Janiece , Segev Dorry , Walston Jeremy , Xue Qian-Li , Szanton Sarah L. 
Published: February 2024

Key PointsPhotovoice, a qualitative method, visually depicted the daily lives of participants with frailty, providing insights into independence and symptom management to guide clinicians and researchers.This photovoice study uncovered subthemes of home safety and organization, revealing potential safety hazards like dialysis fluid storage, and suggests its potential use in geriatric nephrology.The findings emphasize the importance of integrating participant values and goals into care decisions and interventional design in the context of kidney transplant journeys for frail adults.BackgroundOlder adults with frailty and kidney failure face higher waitlist mortality and are more likely to be listed as inactive on the kidney transplant (KT) waitlist. Photovoice is a qualitative participatory research method where participants use photographs to represent their environment, needs, and experiences. It offers unique insight into the lived environment and experience of patients and may offer direction in how to improve functional independence, symptom burden, and KT outcomes in adults with frailty.MethodsThis photovoice study was embedded within a larger intervention adaptation project. Participants with prefrailty or frailty awaiting a KT or recently post-transplant took photographs with Polaroid cameras and wrote short descriptions for 11 prompts. Each participant completed a semistructured interview wherein their photographs were discussed. The team coded and discussed photographs and interviews to determine overarching themes and implications. Focus groups were used to triangulate visual data findings.ResultsSixteen participants completed both the photovoice and the interview. Participants were a mean age of 60.5 years, 31.2% female, 43.4% self-identifying as Black, and 69% were frail. Outcomes were categorized into seven themes: functional space, home safety, medication management, adaptive coping, life-changing nature of dialysis, support, and communication. Visual data clarified and sometimes changed the interpretations of the text alone. Especially within the themes of home safety and functional space, safety hazards not previously recognized in the literature, like dialysis fluid storage, were identified.ConclusionsPhotovoice contextualizes the living conditions and experiences of adults with frailty on the KT journey and could be a useful tool in geriatric nephrology and transplant. Addressing issues of home storage, organization, and accessibility should be explored as potential intervention targets. Incorporating participant values and goals into care decisions and interventional design should be further explored.
PENILAIAN KINERJA IPAL KOMUNAL TERBANGUN DI KOTA CIMAHI
Authors: Sururi Mohamad Rangga , Dirgawati Mila , Wiliana Wili , Widiawati Nining 
Published: February 2024

Permasalahan limbah domestik di Kota Cimahi harus direspon dengan penyediaan sanitasi yang layak, utamanya pengelolaan limbah domestik terpusat (SPALD-T) skala komunal yang menyediakan prasarana dan sarana pengolahan air limbah domestik berbasis masyarakat (Sanimas). Pada 2021, terdapat 14 sistem komunal baru yang harus didata untuk memperbarui data keseluruhan sistem yang terbangun. Oleh karena itu, perlu dilakukan pemutakhiran data dengan sistem informasi yang mengintegrasikan data spasial dan non spasial. Hal ini untuk menunjang ketersediaan database, mengidentifikasi permasalahan dan mengenali potensi perbaikan; serta memberikan masukan dalam menentukan dan merencanakan penempatan lokasi sarana serta prasarana air limbah di masa yang akan datang. Kondisi eksisting sistem jaringan dan sistem pengolahan diperoleh dengan pengamatan dan wawancara. Penilaian sistem dilakukan melalui skoring parameter keberfungsian sistem, jumlah sambungan rumah, kondisi jaringan, kondisi IPAL, kondisi keuangan pengelolaan IPAL, pemelihara IPAL, dan aspek kelembagaan. Selain itu akan di data kepadatan penduduk dan status risiko sanitasi setiap kelurahan di integrasikan secara spasial dengan Arc GIS. Hasil skoring dan analisis Arc Gis keseluruhan sistem menunjukan bahwa sistem baru berfungsi sesuai tujuannya hanya masih lemah dari sisi keuangan dan kelembagaan dengan rata – rata skor 82,05%. Selain itu, terdapat 1 kelurahan berisiko sangat tinggi (zona merah) namun tidak terdapat system baru di wilayah ini. Hasil ini menjadi dasar untuk perencanaan penempatan atau perbaikan sarana serta prasarana air limbah di Kota Cimahi.
GENETIC CHARACTERIZATION IN FOUR INDONESIAN CATTLE BREEDS INFERRED FROM ILLUMINA PARENTAGE SNP MARKERS
Authors: W.P.B. Putra  , Hartati  , Mariyono  , R.R. Noor  , C. Sumantri  , E.T. Margawati  
Published: February 2024

Genetic characterization in native livestock is essential to conserve the genetics standard of livestock for pure-breeding programs. This research aimed to characterize four Indonesian cattle breeds using 156 sites of Parentage SNP Markers, includingARS-USMARC-Parent (119 sites) and ARS-USMARC (37 sites). Total of 113 mixed-sex animals were used for the evaluation, including 16 Bali (Bos javanicus), 16 Madura (Bos indicus), 33 Ongole grade (Bos indicus), and 48 Sumba Ongole (Bos indicus) cattle breeds. Results showed Bali, Madura, and Ongole lineage (Ongole grade and Sumba Ongole) cattle can be discriminated against with the Parentage SNP Markers. The pairwise genetic distance analysis revealed that Bali cattle had a closer genetic relationship with Madura cattle (0.043 - 0.151) than Ongole lineage cattle (0.073 - 0.325). However, the phylogenetic tree explained that the Ongole lineage cattle are grouped into two different clades. At the same time, Bali, Madura and Ongole lineage cattle are grouped into their original cluster. The study suggests that the Parentage SNP Markers can be used to characterize Bali, Madura, and Ongole lineage cattle accurately.
A falta de acompanhamento nutricional interfere no reganho ponderal após dez anos de realização da cirurgia bariátrica?
Authors: Lima Maríllia Raquel de , De Araújo Rolim Francisco Felippe , Paz Teixeira Martins Maria Yasmin , Neves de Lucena Rochelli , Gomes de Sousa Araújo Débora , Cézar de Lima Fernandes Nataly , Queiroga de Sousa Sarah , Arnaud Moura Formiga Walnara , Bandeira Ferraz Alvaro Antonio , Siqueira Silva Fradique Bruna Nolasco 
Published: February 2024

Introdução: A cirurgia bariátrica é um dos tratamentos mais eficazes na perda de peso. No entanto, após o período de 24 meses de cirurgia, é elevada a prevalência de pacientes que apresentam reganho de peso. Objetivo: Avaliar se a ausência do acompanhamento nutricional é um dos fatores que interferem no reganho ponderal de pacientes submetidos ao Bypass Gástrico após dez anos da cirurgia. Métodos: Estudo longitudinal, retrospectivo, com prontuários de pacientes submetidos ao Bypass Gástrico, no Serviço de Cirurgia Geral do Hospital das Clínicas da Universidade Federal de Pernambuco. Coletaram-se variáveis sóciodemográficas, comorbidades associadas, acompanhamento nutricional e atividade física. Na avaliação antropométrica, verificou-se peso pré-cirúrgico, após 24 meses e 10 anos de cirurgia. Os dados foram armazenados em um banco de dados no Excel. Realizaram-se frequências percentuais, média e desvio padrão e se utilizaram os testes Chi-quadrado, Fisher e t de Student, considerando os achados significativos quando p < 0,05. Resultados: Foram avaliados 41 prontuários, sendo 78% mulheres com idade média de 46,27 ± 7,78 anos. O reganho ponderal esteve presente em 70,7% dos pacientes. Não houve significância estatística ao associar reganho ponderal com acompanhamento nutricional periódico, sexo e atividade física. Observou-se menor média de peso nos pacientes acompanhados por nutricionista após 24 meses da cirurgia (p = 0,041). Conclusão: O acompanhamento nutricional periódico promove resultados mais satisfatórios na manutenção da perda de peso.
مــــــــــــدى إسهام الأسرة في تنمية القيم الاجتماعية
Authors: محمد أمحمد المريمي الصديق , علي أبو القاسم صالح مريم 
Published: February 2024

تهدف الدراسة الحالية إلى التعرف على مدى إسهام الأسرة في تنمية القيم الاجتماعية (العفو- الصداقة-التواضع-الكرم) لدى أبنائها ، و التعرف على ما إذا كانت هناك فروق في مدى إسهام الأسرة يُعزى إلى نوعها (طبيعية –غير طبيعية) قامت الدراسة على عيّنة تكونت من 145 تلميذا من تلاميذ المرحلة الأساسية ببلدية الغيران، و استخدمت الدراسة الاستبيان لتحديد مدى إسهاما لأسرة،و استخدمت المتوسطات الحسابية والانحرافات المعيارية، و استخراج قيمة t لقياس الدلالة الفروق في مدى الإسهام تبعا لنوع الأسرة،وتوصلت الدراسة إلى أنّ إسهام الأسرة كان مرتفعا، و جاء في الترتيب الأول إسهامها في تنمية قيمة الكرم ، ويليها قيمة الصداقة ، ثمّ جاءت قيمة التواضع، وأخيرا جاءت قيمة العفو ، كما توصلت الدراسة إلى وجود فروق دالة إحصائيا في مدى الإسهام لصالح الأسرة الطبيعية، وانتهت الدراسة بمجموعة من التوصيات ذات العلاقة بنتائج الدراسة. .
Diagnostic and therapeutic role of endoscopic ultrasound in liver diseases: A systematic review and meta-analysis
Authors: Gadour Eyad , Awad Abeer , Hassan Zeinab , Shrwani Khalid Jebril , Miutescu Bogdan , Okasha Hussein Hassan 
Published: February 2024

BACKGROUND
In hepatology, the clinical use of endoscopic ultrasound (EUS) has experienced a notable increase in recent times. These applications range from the diagnosis to the treatment of various liver diseases. Therefore, this systematic review summarizes the evidence for the diagnostic and therapeutic roles of EUS in liver diseases.
AIM
To examine and summarize the current available evidence of the possible roles of the EUS in making a suitable diagnosis in liver diseases as well as the therapeutic accuracy and efficacy.
METHODS
PubMed, Medline, Cochrane Library, Web of Science, and Google Scholar databases were extensively searched until October 2023. The methodological quality of the eligible articles was assessed using the Newcastle-Ottawa scale or Cochrane Risk of Bias tool. In addition, statistical analyses were performed using the Comprehensive Meta-Analysis software.
RESULTS
Overall, 45 articles on EUS were included (28 on diagnostic role and 17 on therapeutic role). Pooled analysis demonstrated that EUS diagnostic tests had an accuracy of 92.4% for focal liver lesions (FLL) and 96.6% for parenchymal liver diseases. EUS-guided liver biopsies with either fine needle aspiration or fine needle biopsy had low complication rates when sampling FLL and parenchymal liver diseases (3.1% and 8.7%, respectively). Analysis of data from four studies showed that EUS-guided liver abscess had high clinical (90.7%) and technical success (90.7%) without significant complications. Similarly, EUS-guided interventions for the treatment of gastric varices (GV) have high technical success (98%) and GV obliteration rate (84%) with few complications (15%) and rebleeding events (17%).
CONCLUSION
EUS in liver diseases is a promising technique with the potential to be considered a first-line therapeutic and diagnostic option in selected cases.