bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tingkat Pemahaman Atlet Olahraga Tradisional terhadap Sikap Fair Play
Authors: Supriady Andy , Schiff Nancy Trisari , Setiawan Dede 
Published: January 2024

Tujuan penelitian ini adalah untuk mengetahui tingkat pemahaman atlet olahraga tradisional terhadap sikap fair play. Metode yang digunakan ialah Deskriptif kuantitatif dengan bentuk Survey melalui google form (digital) dalam bentuk kuisioner langsung. Populasi pada penelitian ini adalah 14 atlet olahraga tradisional STKIP Pasundan. Instrumen yang digunakan ialah berupa angket kuesioner. Hasil analisis dari keseluruhan indikator pemahaman fair play menujukan bahwa 36% mempunyai tingkat pemahaman fair play yang sangat baik, 43% mempunyai tingkat pemahaman fair play yang baik, sebanyak 7% mempunyai tingkat pemahaman fair play yang cukup baik, dan 14% mempunyai tingkat pemahaman fair play yang sangat kurang. Secara umum tingkat pemahaman fair play atlet olahraga tradisional STKIP Pasundan tergolong baik.
PENGATURAN RESTORATIVE JUSTICE TERHADAP PELAKU DAN KORBAN DALAM PENYELESAIAN PERKARA TINDAK PIDANA ANAK
Authors: Taufan Usyadat , Alam Arief Syahrul , Chaidar Muhamad 
Published: January 2024

Pada hakikatnya hukum dibuat untuk memberikan perlindungan dan keadilan bagi masyarakat luas. Selain jalur litigasi, saat ini pemerintah melalui aparat penegak hukumnya mulai menerapkan metode non ligitasi, yakni penyelesaian perkara pidana diluar peradilan yang disebut restorative justice. Restorative Justice (Keadilan Berbasis Musyawarah) adalah satu pendekatan utama,yang saat ini, berdasarkan Undang-undang Nomor 11 Tahun 2012 tentang Sistem Peradilan Pidana Anak, wajib dilakukan dalam perkara anak yang berhadapan dengan hukum. Pendekatan ini lebih menitikberatkan pada kondisi terciptanya keadilan dan keseimbangan bagi pelaku tindak pidana serta korbannya sendiri. Mekanisme tata cara dan peradilan pidana yang berfokus pada pemidanaan diubah menjadi proses dialog dan mediasi untuik menciptakan kesepakatan atas penyelesaian perkara pidana yang lebih adil dan seimbang bagi pihak korban dan pelaku. Dari latar belakang tersebut, pada penelitian ini terdapat dua rumusan masalah, yaitu 1. Bagaimanakah pengaturan restorative justice terhadap pelaku dan korban dalam penyelesaian perkara tindak pidana anak berdasarkan peraturan perundang-undangan ? 2. Bagaimanakah perlindungan hukum restorative justice terhadap pelaku dan korban dalam penyelesaian perkara tindak pidana anak?. Dalam penelitian ini, peneliti menggunakan metode penelitian yuridis normatif yaitu penelitian hukum kepustakaan yang dilakukan dengan cara meneliti bahan-bahan kepustakaan atau data sekunder saja melalui jenis pendekatan perundang-undangan dan pendekatan konseptual. Dari hasil penelitian ini, penulis menyimpulkan bahwa Keadilan restoratif adalah sebuah konsep pemikiran yang merespons pengembangan sistem peradilan pidana dengan menitikberatkan pada kebutuhan pelibatan masyarakat dan korban yang dirasa tersisihkan dengan mekanisme yang bekerja pada sistem peradilan pidana yang ada pada saat ini. Restorative justice bisa menjadi obat bagi penyelesaian berbagai macam kasus yang melibatkan anak-anak.
The Late-epoch, Intermediate Excitation Spectrum of the Nova V612 Scuti
Authors: Rudy Richard J. , Subasavage John P. , Mauerhan Jon C. 
Published: January 2024

Abstract
Optical and optical/infrared spectra of V612 Scuti from three and four years after outburst show a nova that has sustained nuclear burning and slowly increased in excitation but has not reached the excitation levels exhibited by many novae. The emission lines range in excitation from the nebular lines (e.g., [S iii], [O iii]), up to the coronal lines [Ca viii] and [Si vii]. Distinctive spectral features are particularly strong lines of [Fe vii] and several features of [Fe vi] that include rarely seen infrared lines. A line at 2.04 μm frequently identified with [Al ix] in other novae, is shown to be [Fe v] 2.0401 in V496 Scuti. An analysis with the photoionization code CLOUDY suggests that a largely matter-bounded emission line region is excited by a photosphere of temperature 2.6 × 105 K and luminosity 1 × 104 L
⊙.
A 36-year-old woman with a parathyroid cyst
Authors: Nedeva Iveta , Vodenicharov Vlayko , Karamfilova Vera , Assyov Yavor 
Published: January 2024

Background: Parathyroid cysts are rare entities. They account for less than 0.5% of parathyroid lesions. They are divided into two main groups: functioning and non-functioning.
Case description: We present a 36- year-old woman with complaints of palpitations, sweating, and nervousness of about 2 months’ duration. From an ultrasound of the thyroid gland with data on anechoic formation under the lower pole of the left lobe of the thyroid gland with dimension 14/16/24 mm. Fine needle aspiration (FNA) of the formation was performed with aspiration of about 5 ml of clear liquid and examination of washout. PTH from the washout of the extrathyroidal lesion-1040 pg/ml. A month later with ultrasound data on recurrence of the formation; repeated aspiration of about 5 ml of blood fluid was performed with subsequent application of 1 ml of absolute alcohol intranodal.
Conclusion: Thirty days after the procedure with ultrasound data of slight regression in the dimension: 10/11/20 mm.
Immunité d’exécution et immunité de juridiction : distinction, comparaison, articulation
Authors: Perreau-Saussine Louis 
Published: January 2024

Il est de tradition à la fois de distinguer clairement l’immunité de juridiction et d’exécution des États et de les associer dans une étrange situation à la fois de dépendance et d’indépendance. L’article aborde trois points. D’abord, la distinction des deux immunités, à la fois dans sa version traditionnelle, mais aussi dans sa confrontation avec des questions plus contemporaines (injonctions de Common Law par exemple) ; ensuite, la comparaison des deux immunités, qui repose sur un postulat selon lequel l’exercice de la contrainte sur des biens de l’État constitue une atteinte à la fois plus grave et plus concrète aux intérêts de l’État que des questions d’accès à la justice ; enfin, l’articulation des deux immunités, tout entière construite autour du principe d’indépendance de ces deux immunités consacrée par la Cour internationale de Justice, et qui justifie, notamment, des critères de renonciation distincts pour chacune des deux immunités.
Immunité d’exécution et droits fondamentaux
Authors: Lemaire Sophie 
Published: January 2024

Confrontée aux droits fondamentaux, l’immunité d’exécution est-elle remise en question ? Parce que la Cour internationale de Justice comme la Cour européenne des droits de l’homme estiment que l’immunité d’exécution ne porte pas atteinte aux droits fondamentaux, leur impact est en principe limité. Les zones de résistance paraissent d’autant plus marginales que, si certaines juridictions nationales ont marqué leur dissidence à l’égard de la jurisprudence internationale, leurs positions ont été vivement sanctionnées. Dans la perspective d’évolutions futures, elles méritent néanmoins d’être explorées.
Immunité d’exécution et arbitrage
Authors: Meyer Fabre Nathalie 
Published: January 2024

Le fondement et le régime de l’immunité d’exécution qui protègent les biens souverains ont une cohérence propre que, malgré ses particularités, l’arbitrage n’est pas parvenu à ébranler. Les espoirs fondés sur l’idée qu’en matière d’arbitrage l’exigence de bonne foi serait en quelque sorte magnifiée se sont heurtés aux réalités politiques, diplomatiques et juridiques qui commandent l’usage de la contrainte par un État à l’encontre de biens appartenant à un autre État. Résultat : il n’est en réalité pas plus simple de faire sauter le verrou de l’immunité d’exécution lorsque l’on est muni d’une sentence arbitrale plutôt que d’un jugement étatique.
Immunité d’exécution des États et créances salariales
Authors: Nasom-Tissandier Hélène 
Published: January 2024

Tant le salarié que les créances salariales ont une place privilégiée en droit international. Si l’immunité de juridiction des États est limitée, il n’en va pas de même de l’immunité d’exécution. Peut-on alors aisément accepter le déni de justice résultant de l’immunité d’exécution, la condamnation à des dommages-intérêts restant lettre morte ? Deux voies sont explorées pour tenter d’y remédier : celle d’une possible convergence d’analyse entre immunité de juridiction et immunité d’exécution au regard de certains contentieux du travail, celle d’une conciliation de l’immunité d’exécution et de l’intérêt du salarié par l’engagement de la responsabilité sans faute de l’État du for.
Denrées et marchandises circulant à la fin de la période proto califale au large de la Provence
Authors: Richarté-Manfredi Catherine , Garnier Nicolas 
Published: January 2024

Initié en 2013, ce projet a été conçu pour caractériser les échanges et les contacts dans le sud de la France avec le Dār al-Islām et notamment al-Andalus, en particulier durant le haut Moyen Âge. Les participations interdisciplinaire de C. Capelli (DISTAV, Università degli Studi di Genova) pour la caractérisation archéométrique des charges convoyées ainsi que des responsables des recherches subaquatiques pour l’étude de ces épaves, tels M.-P. Jézégou (DRASSM), S. Ximenes (GRASM) et J.-P. Joncheray (CAS) ont permis à cette contribution de s’inscrire dans un large cadre de réflexion historique, archéologique et économique portant sur la caractérisation des denrées transportées dans ces navires et sur le commerce en Méditerranée occidentale entre la fin du IXe et le début du Xe siècle.
Production agricole, transformation et alimentation dans le Palermitain
Authors: Nef Annliese , Pezzini Elena , Sacco Viva 
Published: January 2024

L’article offre une première synthèse des connaissances disponibles à partir des sources écrites et céramologiques sur la production et la transformation des denrées agricoles en produits alimentaires en Sicile du IXe au XIIe siècle. Il se concentre sur la zone la mieux documentée, le Palermitain, qui a connu des mutations profondes sous l’effet de la croissance sans précédent de la ville de Palerme, devenue capitale insulaire à l’époque islamique, et de l’affirmation de ses élites et de leur investissement, notamment dans la Conca d’oro, la plaine environnant Palerme. Après un retour sur ce premier point, sont ensuite passées en revue les différentes catégories agro‑alimentaires. Les productions dont la présence est le plus souvent attribuée à l’intégration de telle ou telle région à une aire islamique, apparaissent peu nombreuses, mais importantes. De manière générale, plus qu’attester l’introduction de nouveaux produits, cet article suggère outre un investissement des zones circum‑urbaines par les élites palermitaines, une évolution des façons culturales et une intégration de la Sicile à un horizon botanico‑alimentaire islamique.
Antiviral and Anti-Inflammatory Therapeutic Effect of RAGE-Ig Protein against Multiple SARS-CoV-2 Variants of Concern Demonstrated in K18-hACE2 Mouse and Syrian Golden Hamster Models
Authors: Dhanushkodi Nisha Rajeswari , Prakash Swayam , Quadiri Afshana , Zayou Latifa , Srivastava Ruchi , Shaik Amin Mohammed , Suzer Berfin , Ibraim Izabela Coimbra , Landucci Gary , Tifrea Delia F , Singer Mahmoud , Jamal Leila , Edwards Robert A , Vahed Hawa , Brown Lawrence , BenMohamed Lbachir 
Published: January 2024

Abstract
SARS-CoV-2 variants of concern (VOCs) continue to evolve and reemerge with chronic inflammatory long COVID sequelae, necessitating the development of anti-inflammatory therapeutic molecules. Therapeutic effects of the receptor for advanced glycation end products (RAGE) were reported in many inflammatory diseases. However, a therapeutic effect of RAGE in COVID-19 has not been reported. In the present study, we investigated whether and how the RAGE-Ig fusion protein would have an antiviral and anti-inflammatory therapeutic effect in the COVID-19 system. The protective therapeutic effect of RAGE-Ig was determined in vivo in K18-hACE2 transgenic mice and Syrian golden hamsters infected with six VOCs of SARS-CoV-2. The underlying antiviral mechanism of RAGE-Ig was determined in vitro in SARS-CoV-2–infected human lung epithelial cells (BEAS-2B). Following treatment of K18-hACE2 mice and hamsters infected with various SARS-CoV-2 VOCs with RAGE-Ig, we demonstrated (1) significant dose-dependent protection (i.e., greater survival, less weight loss, lower virus replication in the lungs); (2) a reduction of inflammatory macrophages (F4/80+/Ly6C+) and neutrophils (CD11b+/Ly6G+) infiltrating the infected lungs; (3) a RAGE-Ig dose-dependent increase in the expression of type I IFNs (IFN-α and IFN-β) and type III IFN (IFNλ2) and a decrease in the inflammatory cytokines (IL-6 and IL-8) in SARS-CoV-2–infected human lung epithelial cells; and (4) a dose-dependent decrease in the expression of CD64 (FcgR1) on monocytes and lung epithelial cells from symptomatic COVID-19 patients. Our preclinical findings revealed type I and III IFN-mediated antiviral and anti-inflammatory therapeutic effects of RAGE-Ig protein against COVID-19 caused by multiple SARS-CoV-2 VOCs.
Arterial thoracic outlet syndrome in an adolescent
Authors: Kothari Shyam S. , Champaneri Bhavik , Panchal Nirav 
Published: January 2024

ABSTRACT
Arterial thoracic outlet syndrome (aTOS) is rarely diagnosed in children. A 15-year-old boy with recent-onset claudication was found to have aTOS on investigation. Bony abnormality other than the cervical rib might also cause aTOS. Enhanced awareness of aTOS as a cause of vascular symptoms in children is warranted.
Spectrum and outcome of the use of noninvasive ventilation in a pediatric cardiac intensive care unit: A single-center experience
Authors: Das Shubhadeep , Desai Minal , Das Debasis , Dutta Nilanjan , Gajpal Shivani , Sharma Manish 
Published: January 2024

ABSTRACT

Background and Aims:
The pediatric cardiac intensive care unit (PCICU) frequently uses noninvasive ventilation (NIV). There are several reasons for its use, including prophylactic use right after the patient has been extubated. It is also used when patients are experiencing acute respiratory failure due to either cardiac or noncardiac reasons but are still able to maintain their airways. The objective of this study was to understand the spectrum of use of NIV following congenital cardiac surgery and analyze the outcome.

Methods and Results:
A retrospective observational study was conducted in a 14-bed PCICU, reviewing data from August 2019 to August 2022. Among 1750 congenital cardiac surgeries, 523 patients (29.9%) received NIV. The median age of the population was 2.5 months. Factors such as higher Risk-Adjusted Classification for Congenital Heart Surgery-1 category, longer intraoperative cardiopulmonary bypass time, and aortic cross-clamp time were associated with increased NIV use. Preoperative ventilator needs, infections, genetic syndromes, diaphragmatic paralysis, high vasoactive inotrope score (VIS) in the first 24 h, neonatal age, and weight <5 kg were independently associated with increased NIV need. The NIV group had a longer intensive care unit (ICU) stay compared to non-NIV patients. The success rate of NIV was 84%, with 440 successful cases and 83 failures. The mortality rate in the success and failure groups was not significantly different (5.27% vs. 6.0%).

Conclusions:
NIV is widely used in PCICU, but it is associated with longer ICU stays. It proves beneficial after congenital cardiac surgery, especially for patients with specific risk factors. However, NIV may not directly impact mortality rates, suggesting that other factors contribute to patient survival.
In silico prediction, molecular modeling, and dynamics studies on the targeted next-generation sequencing identified genes underlying congenital heart disease in Down syndrome patients
Authors: Carlus Fiona Hannah , Sujatha L. Balasubramaniam , Kumar Anbazhagan Ganesh , Loganathan Lakshmanan , Muthusamy Karthikeyan , Carlus Silas Justin 
Published: January 2024

ABSTRACT

Background:
Individuals with Down syndrome (DS) have a 40%–60% chance of being born with congenital heart disease (CHD). This indicates that CHD in individuals with DS is not solely caused by trisomy 21, and there may be other genetic factors contributing to the development of CHD in these children. A study has identified variants in the specific genes that contribute to the pathogenesis of CHD in children with DS, isolated DS, and the CHD group. Computational studies on these identified variants, which, together with trisomy 21, determine the risk for CHD in DS cases, were limited. Here, we aimed to identify the impact of the identified variants that contribute to the pathogenesis of CHD in children with DS through in silico prediction, molecular modeling, and dynamics studies.

Methodology and Results:
The target single-nucleotide polymorphisms included in the study were examined for pathogenicity, residue conservation, and protein structural changes. The structural predictions were done using I-TASSER, Robetta, SWISS-MODEL, and Phyre2 tools. Further, the predicted models were validated through the PROCHECK server and molecular dynamics simulation using GROMACS software. The conservation analysis conducted on the identified variant highlights its significance in relation to the genetic disorders. Furthermore, a dynamics simulation study revealed the impact of the variant on protein structural stability (≤3 Å), providing valuable insights into its pathogenicity. We have also observed that the structure of the centrosomal protein of 290 kDa gene is relatively unstable, which may be attributed to its exclusive inclusion of helices within its secondary structural components.

Conclusions:
This computational study explores, for the first time, the association between genes and CHD-DS, evaluating the identified specific frameshift variants. The observed pathogenic mutations in CHD-DS patients require further experimental validation and may contribute to the development of prospective drug design research. The insights gained from the structural and functional implications of these variants could potentially serve as a cornerstone in the development of effective treatments for this debilitating condition.
Left sided Scimitar syndrome
Authors: Pandey Sabyasachi , Bharath Adaligere Paraswanath , Mohata Aditya P. , Barthur Ashita , Subramanian Anand P. , Jayranganath Mahimarangaiah 
Published: January 2024

ABSTRACT
The images depict a rare case of Scimitar syndrome involving the left lower pulmonary vein.
Toxicological Studies and Antibacterial Efficacy of Sorghum bicolor Fermented Liquor Extracts of Bambusa tuldoides cv. ventricosa Leaf against Salmonella typhi
Authors: Gabriel Ajobiewe Ruth Adefolakemi Oluwahenyinmi , Okotie Blessing O. , Gabriel Mosope Blessing , Fowora Memunat A. , Cyril Olutayo Christian Mojisola , Ojo Stephen Kayode S. 
Published: January 2024

Abstract

Background:
Bamboo leaf extracted with steep liquor from fermented cereal grains has been used as an ethnomedicine for the treatment of severe typhoid fever in Africa without the proper documentation of its efficacy and side effects.

Aim:
This study embarks on the evaluation of the toxicity and pharmacological safety profile of fermented Sorghum bicolor liquor extract of Bambusa tuldoides cv. ventricosa leaf as an ethnomedicine against Salmonella typhi infection.

Settings and Design:
Reconstituted concentrates of various fermented extracts were used for the minimum inhibitory concentration (MIC) assay. Acute toxicity assay comprised two phases. The bioassay constitutes a total of 25 albino mice randomly distributed into 5 test groups.

Materials and Methods:
Steep liquor from fermented S. bicolor seeds served as the extracting solvent for the leaf of B. tuldoides using Soxhlet apparatus. The determination of both the sensitivity test and MIC assay used different levels. Extracts were orally administered for acute toxicity and dosage determination studies. Extracts were administered at concentrations 25, 50, and 100 mg/mL per day for the bioassays. Application of one-way analysis of variance was used for the determination of the statistical significance of the variations at 0.05 and 0.01 levels.

Results and Conclusions:
The average zones of inhibition were between 15.00 ± 2.34 and 20.00 ± 4.64 mm, and MIC was 12.5 mg/mL for the growth of S. typhi. The extract administered was found to be safe up to 5000 mg/kg body weight dosage. The agglutination result showed a concentration-dependent effectiveness of fermented liquor extract against S. typhi. Therefore, the bamboo leaf extract is efficient for the treatment of S. typhi infection.
Ayurvedic Management of Abnormal Uterine Bleeding in Uterine Fibroid
Authors: Rajoria Kshipra , Singh Sarvesh Kumar 
Published: January 2024

Summary
Abnormal uterine bleeding (AUB) is the most common gynecological problem and is often accompanied with uterine fibroid. Very limited options are available in biomedicine for the AUB. In this reported case, AUB associated with stasis dermatitis was managed on the line of treatment of Vataja Yonivyapada with satisfactory results. This is a case of AUB in uterine fibroid associated with stasis dermatitis in the left lower limb of a 39-year-old female. Gokshuradi Guggulu 750 mg, Shatavari Churna - 2 g, Gairika - 500 mg, and Mukta Shukti Pishti - 500 mg were given twice a day for 18 months, Pushyanuga Churna - 2 g, Chandraprabha Vati - 250 mg, and Arsha Kuthara Rasa 250 mg twice a day for 8 months, and Gokshura churna - 2 g twice a day for 14 months were given to her as oral medication. Jatyadi taila was applied locally twice a day on affected area for 17 months. Four sets of Anuvasana Basti (medicated oil enema), one set of Raktamokshana (therapeutic bloodletting) with Alabu, and three sets of Raktamokshana with Shringa were also adopted in 14 months of treatment duration. After 14 months of treatment, the size of the bulky uterus was reduced from 108 mm × 76 mm × 70 mm in May 2018 to 102 mm × 64 mm × 55 mm in May 2019 and from 7.0 to 6.6 mm in endometrium thickness. The fibroid was resolved, and abnormal bleeding was arrested. This case demonstrates that Ayurveda oral medication and Panchakarma based on the management of Vataja Yonivyapada may be useful in AUB associated with stasis dermatitis.
Phytochemistry and Pharmacology of Selected Species of Smilax L. (Smilacaceae) in India
Authors: Uthaman Neethu , Thomas Valukattil Ponnachan , Thomas Binoy Thundiathu 
Published: January 2024

Abstract

Background:
Medicinal plants have been used in traditional medical practices since prehistoric times. It is popularly known that roots, rhizomes, and leaves of some Smilax species are widely used for treating various diseases such as toothache, muscular pain, urinary diseases, and jaundice.

Methodology:
This review aims to document the information regarding major phytochemicals and pharmacological activity of selected Smilax species in India. Details of different species of Smilax species in India were collected from online databases such as https://wcsp.science.kew.org/(2022), https://powo.science.kew.org (2022), and https://www.ipni.org (2022). All the available information related to phytochemistry and pharmacological activities was collected from electronic databases such as Academic Journals, Springer, PubMed, Google Scholar, ScienceDirect, MEDLINE, Scopus, Web of Science, and other primary and secondary sources.

Results:
Literature survey revealed that members of the genus Smilax possess large quantities of steroids and phenolic compounds and possess various bioactive properties such as antibacterial, antifungal, antioxidant, and analgesic activities.

Conclusion:
This review concludes that more research on the genus Smilax is required to identify and evaluate the presence of potential bioactive constituents, and further investigations may be led to the development of new drugs.