bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal control of the Aux/IAA genes BnIAA32 and BnIAA34 mediates Brassica napus dual shade responses
Authors: Li Yafei , Guo Yiyi , Cao Yue , Xia Pengguo , Xu Dongqing , Sun Ning , Jiang Lixi , Dong Jie 
Published: November 2023

ABSTRACTPrecise responses to changes in light quality are crucial for plant growth and development. For example, hypocotyls of shade‐avoiding plants typically elongate under shade conditions. Although this typical shade‐avoidance response (TSR) has been studied in Arabidopsis (Arabidopsis thaliana), the molecular mechanisms underlying shade tolerance are poorly understood. Here we report that B. napus (Brassica napus) seedlings exhibit dual shade responses. In addition to the TSR, B. napus seedlings also display an atypical shade response (ASR), with shorter hypocotyls upon perception of early‐shade cues. Genome‐wide selective sweep analysis indicated that ASR is associated with light and auxin signaling. Moreover, genetic studies demonstrated that phytochrome A (BnphyA) promotes ASR, whereas BnphyB inhibits it. During ASR, YUCCA8 expression is activated by early‐shade cues, leading to increased auxin biosynthesis. This inhibits hypocotyl elongation, as young B. napus seedlings are highly sensitive to auxin. Notably, two non‐canonical AUXIN/INDOLE‐3‐ACETIC ACID (Aux/IAA) repressor genes, BnIAA32 and BnIAA34, are expressed during this early stage. BnIAA32 and BnIAA34 inhibit hypocotyl elongation under shade conditions, and mutations in BnIAA32 and BnIAA34 suppress ASR. Collectively, our study demonstrates that the temporal expression of BnIAA32 and BnIAA34 determines the behavior of B. napus seedlings following shade‐induced auxin biosynthesis.
Minimally invasive cosmetic procedures for mothers of brides: Strategies and considerations
Authors: Magacho‐Vieira Fabiano Nadson 
Published: November 2023

AbstractThe pivotal role of the bride's mothers in wedding celebrations is an effective motivation to seek cosmetic therapies, making them frequent patients in a dermatologists' offices. Addressing their aesthetic concerns contributes to their holistic well‐being, but faces an intricate relationship between time availability, financial factors, and the critical emotional context. This article underscores the varying behavioral patterns of mothers of brides when seeking aesthetic treatments, providing tailored strategies for effective communication and decision‐making, based on individual personalities. Additionally, this paper presents a specific timeline for the implementation of these interventions, including neuromodulators, collagen stimulators, and fillers. Understanding the unique traits and expectations of this particular population can lead to improved patient satisfaction, enhanced outcomes, and an overall positive experience.
Information Cascades and Threshold Implementation: Theory and an Application to Crowdfunding
Authors: CONG LIN WILLIAM , XIAO YIZHOU 
Published: November 2023

ABSTRACTEconomic interactions often involve sequential actions, observational learning, and contingent project implementation. We incorporate all‐or‐nothing thresholds in a canonical model of information cascades. Early supporters effectively delegate their decisions to a “gatekeeper,” resulting in unidirectional cascades without herding on rejections. Project proposers can consequently charge higher prices. Proposal feasibility, project selection, and information aggregation all improve, even when agents can wait. Equilibrium outcomes depend on crowd size, and project implementation and information aggregation achieve efficiency in the large‐crowd limit. Our key insights hold under thresholds in dollar amounts and alternative equilibrium selection, among other model extensions.
Digitally designed and manufactured sectional custom tray for a patient with microstomia: A case report
Authors: Jagielska Marika , Somohano‐Marquez Tanya , Delgado‐Ruiz Rafael 
Published: November 2023

AbstractMicrostomia presents a challenge for the patient and dental provider. This report describes a partial digital workflow for the fabrication of a mandibular complete denture for a patient with microstomia. Computer‐aided design and computer‐aided manufacturing technology was utilized to 3D print a sectional custom tray with a unique design. The sectional custom tray was used to make a conventional border molded impression of the edentulous arch to fabricate a flexible complete mandibular denture for a 58‐year‐old female patient with scleroderma and microstomia. This treatment resulted in a successful prosthetic outcome and high patient satisfaction.
The joy of being frightened: Fear experience in psychopathy
Authors: Hofmann Miriam J. , Mokros Andreas , Schneider Sabrina 
Published: November 2023

AbstractObjectivePsychopathic traits are associated with abnormalities in fear processing. While traditional theories focus on a lack of fear, Hosker‐Field et al. (2016) provided a new perspective. They suggested that individuals with elevated psychopathic traits may experience threatening situations with appreciation or positivity, resulting in reduced negative fear responses and heightened positive responses (fear enjoyment hypothesis, FEH).MethodOur study aimed to refine Hosker‐Field et al.'s (2016) study design, addressing methodological limitations and improving the inconsistent operationalization of fear experience in the literature. In an online sample of 353 participants from the general population, we examined the relationship between the FEH and relevant psychopathic traits, specifically those derived from the PCL‐R framework (i.e., SRP 4 Factor 1), and from a more trait‐based approach to psychopathy with assumed links to fearlessness (i.e., TriPM Boldness).ResultsBy employing linear mixed effect models, we extended Hosker‐Field et al.'s correlational analysis and provided further evidence for the FEH, particularly in relation to psychopathic traits measured using the PCL‐R framework. The results regarding Boldness, however, are somewhat inconclusive.ConclusionThe present study enhances existing research on fear deficits in psychopathy by assessing the subjective experience of individuals facing threat.
Almost half of the Gymnura van Hasselt, 1823 species are unknown: Phylogeographic inference as scissors for cutting the hidden Gordian knot and clarify their conservation status
Authors: Gales Suellen M. , Parsons Kristene T. , Biesack Ellen E. , Ready Jonathan , Siccha‐Ramirez Raquel , Rosa Leonardo C. , Rosa Ricardo , Rotundo Matheus M. , Bills Roger , Rodrigues Alan Erik S. , Rodrigues‐Filho Luis Fernando S. , McDowell Jan , Sales João Bráullio L. 
Published: November 2023

AbstractGymnurid rays are found in tropical, subtropical, and temperate regions around the world, where they are associated with sandy or muddy bottoms in coastal areas, being easily distinguished from other rays by the width of the disc. In recent years, the systematics of this family have been revised extensively. However, there has been no comprehensive molecular review of the family based on an adequate sample of species and localities, which may have obscured the presence of distinct evolutionary lineages. The present study was based on samples of 12 of the 13 valid species of the genus Gymnura, which were used for a multilocus reconstruction of the evolutionary history of the family Gymnuridae. Our results indicate the existence of several cryptic gymnurid lineages, within the species Gymnura micrura, Gymnura lessae, Gymnura altavela, and Gymnura poecilura. Also, we indicate that only half of the species that compose the genus are known, as well their conservation status. The analyses also indicate that the gymnurids originated during the Paleocene, with events of dispersal and vicariance occurring through the formation of oceanographic barriers, and species diversification peaking during the Oligocene and Miocene. The results of the present study reinforce the need for a comprehensive revision of the systematics of the family, in particular, the widely distributed species that are considered valid taxa, but may, in fact, represent different cryptic species. The inadequate classification of this cryptic diversity may have negative implications for the development of effective conservation measures.
3D printed meat and the fundamental aspects affecting printability
Authors: Moparthi Sai Sathvika , L. Gokul Krishna , Karyappa Rahul , Upadhyay Rituja 
Published: November 2023

AbstractThree‐dimensional (3D) printing, one of the forms of additive manufacturing, has become a popular trend worldwide with a wide range of applications including food. The technology is adaptable and meets foods nutritional and sensory needs allowing meat processing to reach a sustainable level, technology addressing the food requirement of the ever‐increasing population and the fast‐paced lifestyle by reducing food preparation time. By minimizing food waste and the strain on animal resources, technology can help to create a more sustainable economy and environment. This review article discusses the 3D printing process and various 3D printing techniques used for food printing, such as laser powder bed fusion, inkjet food printing, and binder jetting, a suitable 3D technique used for meat printing, such as extrusion‐based bioprinting. Moreover, we discuss properties that affect the printability of meat and its products with their applications in the meat industry, 3D printing market potential challenges, and future trends.
Effects of soaked hay on lung function and airway inflammation in horses with severe asthma
Authors: Westerfeld Roxane , Payette Flavie , Dubuc Valérie , Manguin Estelle , Picotte Khristine , Beauchamp Guy , Bédard Christian , Leclere Mathilde 
Published: November 2023

AbstractBackgroundReducing inhaled dust particles improves lung function in horses with severe asthma. Soaked hay is commonly used by owners, but its efficacy in improving lung function and inflammation has not been documented.ObjectivesTo measure the effects of soaked hay and alfalfa pellets in horses with severe asthma.AnimalsTen adult horses with severe asthma from a research colony.MethodsProspective controlled trial. Horses in clinical exacerbation were housed indoors and allocated to be fed either soaked hay (n = 5) or alfalfa pellets (n = 5) for 6 weeks. Soaked hay was immersed for 45 minutes and dried out hay was discarded between meals. Pulmonary function and clinical scores were measured before and after 2, 4, and 6 weeks. Tracheal mucus scores and bronchoalveolar lavages were performed before and after 6 weeks. Lung function was analyzed with a linear mixed model using log‐transformed data.ResultsLung resistance decreased from (median (range)) 2.47 (1.54‐3.95) to 1.59 (0.52‐2.10) cmH2O/L/s in the pellets group and from 1.89 (1.2‐3.54) to 0.61 (0.42‐2.08) cmH2O/L/s in the soaked hay group over the 6‐week period for an average difference of 1.06 cmH2O/L/s for pellets (95% confidence interval [95% CI]: 0.09‐2.04, P = .03, not significant after correction) and 1.31 cmH2O/L/s for soaked hay (95% CI: −0.23 to 2.85, P < .001, significant).Conclusion and Clinical ImportanceSoaked hay can control airway obstruction in horses with severe asthma. The strict protocol for soaking and discarding dried‐out hay in this study could however be considered too great of an inconvenience by owners.
Physcomitrium patens response to elevated CO2 is flexible and determined by an interaction between sugar and nitrogen availability
Authors: Mohanasundaram Boominathan , Koley Somnath , Allen Doug K. , Pandey Sona 
Published: November 2023

Summary

Mosses hold a unique position in plant evolution and are crucial for protecting natural, long‐term carbon storage systems such as permafrost and bogs. Due to small stature, mosses grow close to the soil surface and are exposed to high levels of CO2, produced by soil respiration. However, the impact of elevated CO2 (eCO2) levels on mosses remains underexplored.

We determined the growth responses of the moss Physcomitrium patens to eCO2 in combination with different nitrogen levels and characterized the underlying physiological and metabolic changes.

Three distinct growth characteristics, an early transition to caulonema, the development of longer, highly pigmented rhizoids, and increased biomass, define the phenotypic responses of P. patens to eCO2. Elevated CO2 impacts growth by enhancing the level of a sugar signaling metabolite, T6P. The quantity and form of nitrogen source influences these metabolic and phenotypic changes. Under eCO2, P. patens exhibits a diffused growth pattern in the presence of nitrate, but ammonium supplementation results in dense growth with tall gametophores, demonstrating high phenotypic plasticity under different environments.

These results provide a framework for comparing the eCO2 responses of P. patens with other plant groups and provide crucial insights into moss growth that may benefit climate change models.
Multivariate analysis of alveolar bone dehiscence and fenestration in anterior teeth after orthodontic treatment: A retrospective study
Authors: Luo Nan , Chen Yanxi , Li Lingfeng , Wu Yan , Dai Hongwei , Zhou Jianping 
Published: November 2023

AbstractObjectiveTo compare the prevalence of fenestration and dehiscence between pre‐ and post‐orthodontic treatment and to explore the factors related to fenestration and dehiscence in the anterior teeth after treatment.MethodsThis study included 1000 cone‐beam computed tomography (CBCT) scans of 500 patients before (T1) and after (T2) orthodontic treatment. These images were imported into Dolphin 11.9 software to detect alveolar fenestration and dehiscence in the anterior teeth area. The chi‐square test and Fisher's exact test were performed to compare the prevalence of alveolar bone defects between time points T1 and T2. A total of 499 patients were selected for logistic regression analysis to examine the correlation among age, sex, crowding, sagittal facial type, extraction, miniscrew use and fenestration or dehiscence post‐treatment.ResultsExcept for the maxillary lingual fenestration and labial fenestration of mandibular canines, a significant change in the prevalence of fenestration and dehiscence was noted between time points T1 and T2 (P < .025). Multinomial logistic regression showed that age, miniscrew use and extraction highly influenced the prevalence of anterior lingual dehiscence (P < .05). Dehiscence of the mandibular labial side (skeletal Class III vs. I, OR = 2.368, P = .000) and fenestration of the mandibular lingual side (skeletal Class II vs. I, OR = 2.344, P = .044) were strongly correlated with the sagittal facial type. Dehiscence of the maxillary labial side (moderate vs. mild, OR = 1.468, P = .017) was significantly associated with crowding.ConclusionsOlder age, maxillary moderate crowding, skeletal Class III, extraction and miniscrew potentially significantly affect the prevalence of anterior teeth dehiscence. Adult females, skeletal Class III patients on the mandibular labial side and skeletal Class II patients on the mandibular lingual side should be monitored for anterior teeth fenestration.
Effects of daily versus weekly teriparatide for medication‐related osteonecrosis of the jaw: A case–control study
Authors: Kim Kang‐Min , Kim Sehyang , Hwang Hyun , Kim Hey‐Yun , Kim Dohyun , Park Jung‐Hyun , Choo HyeRan , Kim Jin‐Woo 
Published: November 2023

AbstractIntroductionMedication‐related osteonecrosis of the jaw (MRONJ) is uncommon but can result in severe destruction of the jaw. This case–control study investigated the therapeutic effects of daily or weekly administration of teriparatide in the management of MRONJ using a cohort for osteonecrosis of the jaw.MethodsPatients who were diagnosed with MRONJ and consented to teriparatide administration were assigned either to a group of daily injection or of weekly injection and completed a 4‐week course of injection preoperatively and at least an 8‐week course postoperatively. The control group received either the intraoperative rhBMP treatment (CG_BMP) or no additional perioperative treatment (CG_noBMP). The state of MRONJ was evaluated 2 months (T1) and 6 months (T2) postoperatively for all participants.ResultsEither group of daily injection (8.35 weeks ± 1.58; n = 17) or weekly injection (9.17 ± 3.79; n = 12) showed significantly faster healing than those of CG_BMP (14.40 ± 6.08; n = 25) or CG_noBMP (15.79 ± 9.79; n = 39). MRONJ was resolved completely in 24 out of 29 participants who completed the course of teriparatide injections, whereas 46.9% of CG showed delayed resolution. Multiple regression analysis indicated 7.50 times (95% CI, 1.77–31.82) more likelihood of complete resolution of MRONJ for participants with teriparatide injections.ConclusionA course of daily or weekly administration of teriparatide injections may improve treatment outcomes for patients with MRONJ.
The bidirectional effect of neutrophils on periodontitis model in mice: A systematic review
Authors: Liu Siyan , Chen Yingyi , Jiang Yiyang , Du Juan , Guo Lijia , Xu Junji , Liu Yitong , Liu Yi 
Published: November 2023

AbstractObjectiveTo evaluate the regulatory role of neutrophils as the first line of host immune defense in the periodontal microenvironment of mice.MethodsA systematic search was performed using PubMed, Web of Science, and ScienceDirect databases for articles published between 2012 and 2023. In this review, articles investigating the effect of neutrophils on alveolar bone resorption in a mouse model of periodontitis were selected and evaluated according to eligibility criteria. Important variables that may influence outcomes were analyzed.ResultsEleven articles were included in this systematic review. The results showed that because of their immune defense functions, the functional homeostasis of local neutrophils is critical for periodontal health. Neutrophil deficiency aggravates alveolar bone loss. However, several studies have shown that excessive neutrophil infiltration is positively correlated with alveolar bone resorption caused by periodontitis in mice. Therefore, the homeostasis of neutrophil function needs to be considered in the treatment of periodontitis.ConclusionsPooled analysis suggests that neutrophils play a bidirectional role in periodontal tissue remodeling in mouse periodontitis models. Therefore, targeted regulation of local neutrophil function provides a novel strategy for the treatment of periodontitis.
Exploring collaboration dynamics and representation in environmental justice councils
Authors: Ambrose Graham 
Published: November 2023

AbstractA collaboration's ability to convene diverse stakeholders and knowledge is often associated with success. However, a more nuanced evaluation of representation is needed to understand if meeting‐level factors (e.g., who attends as well as including facilitators or external technical experts) influence representation. This article examines representation via two‐way communication in meetings to explore: (1) patterns of discussion across sectors (i.e., appointed citizens, agency delegates, and external stakeholders), (2) how patterns of discussion change given attendance differences across sectors, and (3) how meeting‐level factors associate with observed discussion patterns. Using meeting‐level data, across three US, state‐level, legislatively‐mandated environmental justice councils, results suggest: (1) sectors have different patterns of how much and with whom they discuss, (2) retreat meetings increase discussion for all, and (3) other meeting‐level factors and discussion patterns are narrowly focused to specific sectors. The discussion applies the findings of this study to the broader field of collaborative governance.
Fatty alcohols, a minor component of the tree tobacco surface wax, are associated with defence against caterpillar herbivory
Authors: Negin Boaz , Shachar Lior , Meir Sagit , Ramirez Claudio C. , Rami Horowitz A. , Jander Georg , Aharoni Asaph 
Published: November 2023

AbstractDespite decades of research resulting in a comprehensive understanding of epicuticular wax metabolism, the function of these almost ubiquitous metabolites in plant–herbivore interactions remains unresolved. In this study, we examined the effects of CRISPR‐induced knockout mutations in four Nicotiana glauca (tree tobacco) wax metabolism genes. These mutations cause a wide range of changes in epicuticular wax composition, leading to altered interactions with insects and snails. Three interaction classes were examined: chewing herbivory by seven caterpillars and one snail species, phloem feeding by Myzus persicae (green peach aphid) and oviposition by Bemisia tabaci (whitefly). Although total wax load and alkane abundance did not affect caterpillar growth, a correlation across species, showed that fatty alcohols, a minor component of N. glauca surface waxes, negatively affected the growth of both a generalist caterpillar (Spodoptera littoralis) and a tobacco‐feeding specialist (Manduca sexta). This negative correlation was overshadowed by the stronger effect of anabasine, a nicotine isomer, and was apparent when fatty alcohols were added to an artificial lepidopteran diet. By contrast, snails fed more on waxy leaves. Aphid reproduction and feeding activity were unaffected by wax composition but were potentially affected by altered cutin composition. Wax crystal morphology could explain the preference of B. tabaci to lay eggs on waxy wild‐type plants relative to both alkane and fatty alcohol‐deficient mutants. Together, our results suggest that the varied responses among herbivore classes and species are likely to be a consequence of the co‐evolution that shaped the specific effects of different surface wax components in plant–herbivore interactions.
Pulmonary vein stenosis in heart transplant patients
Authors: Choi Connie , Morray Brian H. , Ahmed Humera , Kemna Mariska 
Published: November 2023

AbstractBackgroundPulmonary vein stenosis (PVS) is a rare pediatric condition associated with significant mortality and morbidity. PVS in patients following heart transplant (HT) has not yet been described.MethodsPatients who had clinically significant PVS following a heart transplant during the time period of April 1, 2013 to April 30, 2023, at Seattle Children's Hospital were identified. Clinically significant PVS was defined as an atretic vein or a vein with a gradient of ≥4 mmHg across at least one vein by echocardiogram or during cardiac catheterization. Patients who had a diagnosis of PVS prior to their transplant were excluded. A total of six patients were identified. We collected clinical data on these patients from their pre‐transplant course to their most recent status.ResultsThe median age at HT was 7.5 months (range 2–13 months). The median time from HT to diagnosis of PVS was 3.5 months (range 0.3–13 months). At the last follow‐up, the patients had had two to five pulmonary vein interventions, and there were no mortalities. The donor‐to‐recipient weight and total cardiac volume (TCV) ratios were less than 2.0 in five of six of the patients.ConclusionsPVS is a rare complication that is associated with patients who undergo HT during infancy. PVS develops soon after HT and screening should occur accordingly. Interestingly, high donor‐to‐recipient weight and TCV ratios are not necessarily associated with the development of PVS. Further work will need to be performed in order to determine the significance of PVS in post‐HT patients.