bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of radiation and viscous dissipation using the Galerkin method over a vertical porous plate with variation in temperature
Authors: Mangamma Ch. , Appidi Lakshmi , Malga Bala Siddulu , Kumar P. Pramod , Matta Sweta 
Published: January 2024

AbstractIn the presence of viscous dissipation and radiation effects, a numerical analysis is performed for an unsteady‐free convective, radiative, chemically reactive, radiation absorption, viscous, incompressible, and electrically conducting fluid passing through an exponentially accelerating vertical porous plate. Numerical methods are used to solve the collection of nondimensional governing equations and their boundary conditions. Graphs are used to study the effects of different physical characteristics on flow quantities. Tables are used to study the differences in skin friction, the Sherwood number, and the Nusselt number for the physical interest. The analysis and explanation of the fluctuation in radiation and flow parameters on velocity and temperature gradient profiles through graphs using the Galerkin technique is the novelty of this work. For the magnetic, Prandtl, heat sink, radiation, Schmidt, and chemical reaction parameters, skin friction is significantly higher; however, for the Grashof, modified Grashof, permeability, radiation absorption, Dufour, and Soret numbers, skin friction has the opposite tendency.
Maternal and fetal factors associated with stillbirth in singleton pregnancies in 13 hospitals across six states in India: A prospective cohort study
Authors: Boo Yebeen Ysabelle , Bora Amrit K. , Chhabra Shakuntala , Choudhury Saswati S. , Deka Gitanjali , Kakoty Swapna , Kumar Pramod , Mahanta Pranabika , Minz Bina , Rani Anjali , Rao Sereesha , Roy Indrani , Solomi V. Carolin , Verma Ashok , Zahir Farzana , Deka Rupanjali , Kurinczuk Jennifer J. , Nair Manisha ,   the MaatHRI collaborators
Published: January 2024

AbstractObjectiveThis study aimed to investigate the incidence of and risk factors for stillbirth in an Indian population.MethodsWe conducted a secondary data analysis of a hospital‐based cohort from the Maternal and Perinatal Health Research collaboration, India (MaatHRI), including pregnant women who gave birth between October 2018–September 2023. Data from 9823 singleton pregnancies recruited from 13 hospitals across six Indian states were included. Univariable and multivariable Poisson regression analysis were performed to examine the relationship between stillbirth and potential risk factors. Model prediction was assessed using the area under the receiver‐operating characteristic (AUROC) curve.ResultsThere were 216 stillbirths (48 antepartum and 168 intrapartum) in the study population, representing an overall stillbirth rate of 22.0 per 1000 total births (95% confidence interval [CI]: 19.2–25.1). Modifiable risk factors for stillbirth were: receiving less than four antenatal check‐ups (adjusted relative risk [aRR]: 1.75, 95% CI: 1.25–2.47), not taking any iron and folic acid supplementation during pregnancy (aRR: 7.23, 95% CI: 2.12–45.33) and having severe anemia in the third trimester (aRR: 3.37, 95% CI: 1.97–6.11). Having pregnancy/fetal complications such as hypertensive disorders of pregnancy (aRR: 1.59, 95% CI: 1.03–2.36), preterm birth (aRR: 4.41, 95% CI: 3.21–6.08) and birth weight below the 10th percentile for gestational age (aRR: 1.35, 95% CI: 1.02–1.79) were also associated with an increased risk of stillbirth. Identified risk factors explained 78.2% (95% CI: 75.0%–81.4%) of the risk of stillbirth in the population.ConclusionAddressing potentially modifiable antenatal factors could reduce the risk of stillbirths in India.
Accuracy of Dare's formula in estimating fetal birth weight in pregnant women
Authors: Kumari Vinita , Singh Abha 
Published: January 2024

AbstractObjectiveTo evaluate the accuracy of Dare's formula in estimating fetal birth weight in pregnant women.MethodsA prospective study was conducted at a tertiary care hospital in New Delhi after institutional ethical committee clearance. In all, 175 pregnant women with singleton pregnancies of 37 weeks or more were included. The aim was to assess fetal birth weight by Dare's formula and ultrasonography. This estimated fetal weight (EFW) was compared with actual birth weight (ABW) of newborn.ResultsEstimated fetal birth weight by Dare's formula was within 10% of ABW in 77 (44.00%) cases. Meanwhile in the majority (98; 56.00%), EFW by Dare's formula was not within 10% of ABW. The proportion of EFW by ultrasonography within 10% and not within 10% of ABW were comparable (50.29% [88] and 49.71% [87], respectively).ConclusionDare's formula can be used by medical personnel as a clinical method in routine prenatal care to estimate fetal weight, for better management of women in labor to decrease the maternal and neonatal mortality and morbidity.
Association between earthquakes and perinatal outcomes: A systematic review and meta‐analysis
Authors: Wada Yoshimitsu , Watanabe Jun , Yamamoto Norio , Kubota Takafumi , Kamijo Kyosuke , Hirano Daishi , Takahashi Hironori , Fujiwara Hiroyuki 
Published: January 2024

AbstractBackgroundEvidence for the association between earthquakes and adverse perinatal outcomes is limited.ObjectivesTo evaluate the association between earthquakes and perinatal outcomes including preterm birth and low birth weight.Search StrategyWe searched studies using MEDLINE, Cochrane Central Register of Controlled Trials, EMBASE, World Health Organization International Clinical Trials Platform Search Portal, and ClinicalTrials.gov on February 9, 2023.Selection CriteriaWe included before‐and‐after studies that evaluated the associations between earthquakes and perinatal outcomes in women living in affected areas.Data Collection and AnalysisTwo independent reviewers extracted data. We calculated the pooled odds ratio (OR) with the random‐effects model. We analyzed outcomes in subgroups of Asians and others. We evaluated the certainty of evidence with the Grading of Recommendations Assessment, Development and Evaluation system.Main ResultsWe included 2 607 405 women in 13 studies. Earthquakes may not increase preterm birth (nine studies, 1 761 760 participants: OR 1.10, 95% confidence interval [CI] 0.98–1.24, low certainty of evidence) or low birth weight (seven studies, 1 753 891 participants: OR 1.10, 95% CI 0.94–1.28, low certainty of evidence). Subgroup analyses showed that earthquakes may be associated with an increase of preterm birth among populations in Asia (OR 1.44, 95% CI 1.07–1.95), but this was not evident in others (OR 0.93, 95% CI 0.83–1.05).ConclusionsPerinatal outcomes might not change after earthquakes. Further research on the association between earthquakes and perinatal outcomes, combined with an assessment of the characteristics of the region, is needed.
Assessment and cost analysis of mycoremediated textile effluent for irrigation
Authors: Rajhans Geetanjali , Sen Sudip Kumar , Pallavi Preeti , Raut Sangeeta 
Published: January 2024

AbstractIn the current study, mycoremediated textile effluents were used for irrigation in a cultivation system to promote resource recycling and cost‐effective spinach production. The raw textile effluents from two different textile mills were decolorized by 93.2 and 94.5%, respectively, as well as mineralized by the immobilized novel fungus Geotrichum candidum. Subsequently, both the treated effluents, treated textile effluent 1 (TTE1) and treated textile effluent 2 (TTE2), were used to cultivate spinach. The results indicated that irrigation with TTE1 and TTE2 resulted in ~9% higher spinach yields compared with the control. Moreover, the water use efficiency with the TTE1 and TTE2 treatments was ~1.2 times better than that with the control. The need for fertilizers in the case of spinach cultivation with treated effluents was compensated by the textile effluents as a result of the breakdown and mineralization of the effluent by immobilized G. candidum. Notably, the energy content, dietary fiber and protein content of spinach irrigated with mycoremediated textile effluent were substantially elevated, with values of 34 kcal/100 g−1, 3.4 g 100 g−1 and 6.92 g 100 g−1, respectively. The preliminary cost analysis indicated that the costs of the whole process (from treatment to irrigation) were approximately US$0.35‐0.38 m−3 (INR 28.22–30.45 m−3) of textile effluent. The study concluded that the mycoremediated textile effluent could be efficiently applied for agronomic usages.
An economic analysis of the “Buy Local” trend
Authors: Ray Susweta , Giannakas Konstantinos 
Published: January 2024

AbstractThis study develops a novel framework of heterogeneous consumers and producers to analyze the market and welfare impacts of the “Buy Local” trend. Analytical results show that the trend's impacts depend on the size and type of the locality; that is, whether the locality is an exporter or an importer of the relevant products. For instance, while the trend benefits both consumers and producers of large localities, it leaves producers of small exporting localities unaffected. The presence of the trend in large localities affects also outside consumers and producers with the welfare impact depending on the type of locality.
Adolescents' effort in vocational education and training and upper secondary general education: Analyses of stability, determinants, and group differences
Authors: Neuenschwander Markus P. , Ramseier Lukas , Hofmann Jan 
Published: January 2024

AbstractIntroductionThe effort adolescents make determines the risk for dropping out of vocational education and training (VET) early and their chances of graduating upper secondary education. Studies have shown that adolescents' efforts decrease during the transition to upper secondary general education and increases for the transition to VET. In this study, we examined adolescent self‐efficacy in lower secondary education, adolescent‐instructor relationship (AIR) in VET and general education, and perceived person–environment fit (PEF) as predictors of adolescent effort.MethodWe calculated two longitudinal multigroup structural equation models. Group 1 comprised 1266 (mean age in T1 = 15.7 years; female: 44%) lower secondary education graduates who moved on to VET with two learning contexts, company and vocational school in Switzerland. Group 2 included 517 (mean age in T1 = 15.7 years; female: 44%) lower secondary education graduates who moved on to upper secondary general education and thus stayed in a school. Adolescents' survey data was collected in 2016 and 2017.ResultsSelf‐efficacy in lower secondary education and AIR in upper secondary education indirectly predicted effort in upper secondary education via PEF, controlling for effort in lower secondary education. Findings were similar for general education and vocational school. However, the effects differed between company and general education (moderation). The positive effect of AIR on PEF was statistically significantly weaker for adolescents in general education than for adolescents in VET and their company learning context.ConclusionWe discuss strategies to enhance adolescents' efforts in upper secondary education.
Overcoming challenges associated with identifying FBN1 deep intronic variants through whole‐genome sequencing
Authors: Kim Jee Ah , Jang Mi‐Ae , Jang Shin Yi , Kim Duk‐Kyung , Kim Young‐gon , Kim Jong‐Won , Park Taek Kyu , Jang Ja‐Hyun 
Published: January 2024

AbstractBackgroundMarfan syndrome (MFS), caused by pathogenic variants of FBN1 (fibrillin‐1), is a systemic connective tissue disorder with variable phenotypes and treatment responsiveness depending on the variant. However, a significant number of individuals with MFS remain genetically unexplained. In this study, we report novel pathogenic intronic variants in FBN1 in two unrelated families with MFS.MethodsWe evaluated subjects with suspected MFS from two unrelated families using Sanger sequencing or multiplex ligation‐dependent probe amplification of FBN1 and/or panel‐based next‐generation sequencing. As no pathogenic variants were identified, whole‐genome sequencing was performed. Identified variants were analyzed by reverse transcription‐PCR and targeted sequencing of FBN1 mRNA harvested from peripheral blood or skin fibroblasts obtained from affected probands.ResultsWe found causative deep intronic variants, c.6163+1484A>T and c.5788+36C>A, in FBN1. The splicing analysis revealed an insertion of in‐frame or out‐of‐frame intronic sequences of the FBN1 transcript predicted to alter function of calcium‐binding epidermal growth factor protein domain. Family members carrying c.6163+1484A>T had high systemic scores including prominent skeletal features and aortic dissection with lesser aortic dilatation. Family members carrying c.5788+36C>A had more severe aortic root dilatation without aortic dissection. Both families had ectopia lentis.ConclusionVariable penetrance of the phenotype and negative genetic testing in MFS families should raise the possibility of deep intronic FBN1 variants and the need for additional molecular studies. This study expands the mutation spectrum of FBN1 and points out the importance of intronic sequence analysis and the need for integrative functional studies in MFS diagnosis.
Empathy rules, maps and paths: A qualitative exploration of the factors that facilitate or inhibit empathy and prosocial responding among youth
Authors: Silke Charlotte , Brady Bernadine , Dolan Pat , Boylan Ciara 
Published: January 2024

AbstractThe aim of this study is to explore young people's perspectives on the factors that facilitate or inhibit empathy and prosocial responding among youth. Qualitative focus groups (n = 29) were undertaken with Irish young people aged 13–17 years relating to their views on the factors that facilitate or inhibit the expression of empathy. Parents, friends, and social media were found to be key influences, whereas barriers identified included societal norms, gender norms, lack of skill, or knowledge and target characteristics. This research provides important insights into adolescents’ perceptions of the social correlates of empathy. Concepts from the sociology of empathy, such as empathy maps and paths, are helpful in drawing out the implications for future research and practice.
Optimal conditions for 2‐phenylethanol production from l‐phenylalanine by Acinetobacter soli ANG344B
Authors: Bernardino Ana RS , Torres Cristiana AV , Grosso Filipa , Peixe Luísa , Reis Maria AM 
Published: January 2024

AbstractBACKGROUND2‐Phenylethanol (2‐PE) is a valuable flavor compound renowned for its rose‐like scent and widespread application in the cosmetic, perfume and food industries. While it can be naturally sourced from plants, the majority is currently produced through chemical synthesis, leading to environmental concerns. As an ecofriendly alternative, biotechnological production of 2‐PE presents a promising solution, yielding a natural product.RESULTSIn this work, the newly isolated bacterium Acinetobacter soli ANG344B was used to produce 2‐PE from l‐phenylalanine (L‐Phe), using glucose as carbon source, aiming to determine the best conditions for cellular growth and aroma production. The optimal conditions for Acinetobacter cultivation and 2‐PE production were 30 °C and pH 7. Further, yeast extract proved to be a key element for 2‐PE production. The concentration of L‐Phe that maximizes 2‐PE volumetric productivity was found to be 5 g L−1, present in the cultivation media from the beginning of the cultivation. Under these conditions 2.14 ± 0.18 g L−1 of the aroma compound was produced, which is the highest concentration obtained for a wild‐type bacterium. The toxicity of 2‐PE was also evaluated, revealing that cellular growth of A. soli ANG344B was adversely affected at concentrations above 1 g L−1, and beyond 4 g L−1 no cellular growth was observed.CONCLUSIONBy elucidating the crucial factors affecting 2‐PE production by A. soli ANG344B, we pave the way for the development of biotechnological strategies to harness its potential as a natural and sustainable aroma compound. © 2024 Society of Chemical Industry (SCI).
Identification of stable reference genes for relative quantification of long RNA expression in urinary extracellular vesicles
Authors: Zhu Xiao‐Xiao , Shen An‐Ran , Li Ning , Feng Song‐Tao , Tang Tao‐Tao , Zhang Yue , Jing Jing , Zhong Xin , Xie Li‐Jun , Huang Sheng‐Lin , Liu Bi‐Cheng , Lv Lin‐Li 
Published: January 2024

AbstractUrinary extracellular vesicles (uEVs) are rich in valuable biomolecule information which are increasingly recognized as potential biomarkers for various diseases. uEV long RNAs are among the critical cargos capable of providing unique transcriptome information of the source cells. However, consensus regarding ideal reference genes for relative long RNAs quantification in uEVs is not available as of date. Here we explored stable reference genes through profiling the long RNA expression by RNA‐seq following unsupervised analysis and validation studies. Candidate reference genes were identified using four algorithms: NormFinder, GeNorm, BestKeeper and the Delta Ct method, followed by validation. RNA profile showed uEVs contained abundant long RNAs information and the core transcriptome was related to cellular structures, especially ribosome which functions mainly as translation, protein and RNA binding molecules. Analysis of RNA‐seq data identified RPL18A, RPL11, RPL27, RACK1, RPSA, RPL41, H1‐2, RPL4, GAPDH, RPS27A as candidate reference genes. RT‐qPCR validation revealed that RPL41, RPSA and RPL18A were reliable reference genes for long RNA quantification in uEVs from patients with diabetes mellitus (DM), diabetic nephropathy (DN), IgA nephropathy (IgAN) and prostate cancer (PCA). Interestingly, RPL41 also outperformed traditional reference genes in renal tissues of DN and IgAN, as well as in plasma EVs of several types of cancers. The stable reference genes identified in this study may facilitate development of uEVs as novel biomarkers and increase the accuracy and comparability of biomarker studies.
Export stability and adolescent fertility rate
Authors: Huang Lili , Gao Qingyi , Fan Jiachen , Zhu Jingwen , Hong Zhenmu 
Published: January 2024

AbstractThis paper studies the effect of export stability on the adolescent fertility rate. The test results show that the improvement of export stability will decrease the adolescent fertility rate of exporting countries through four mechanisms: raising female labour income, increasing health expenditure, promoting urbanization and strengthening female education empowerment. Compared to developed or high‐income countries, the impact of export stability in developing or low‐income countries is more substantial. The increase in export scale will strengthen the impact of export stability on adolescent fertility rates. The findings of this article can help countries to govern the adolescent fertility rate further.
From expanding financial services to tackling poverty in West African Economic and Monetary Union: The accelerating role of mobile money
Authors: Senou Melain Modeste , Houensou Denis Acclassato 
Published: January 2024

AbstractThis paper aims to assess the accelerating role of digital technology in fighting poverty through financial inclusion in the countries of West African Economic and Monetary Union (WAEMU). Based on a sample of the adult population from the World Bank's Findex database, we estimate a recursive bivariate probit model that addresses endogeneity. The findings show that the regular usage of mobile money as well as the purpose of mobile money usage including saving, borrowing, remittance and their combinations increase diversely and significantly the probability of short‐term poverty alleviation in WAEMU. In addition, the change in poverty status can be indirectly due to certain driving factors of mobile money usage including mainly the ownership of mobile phones.
Cerebral Sinus Hemodynamics in Adults Revealed by 4D Flow MRI
Authors: Dai Chihang , Zhao Pengfei , Ding Heyu , Lv Han , Qiu Xiaoyu , Tang Ruowei , Xu Ning , Huang Yan , Han Xu , Yang Zhenghan , Wang Zhenchang 
Published: January 2024

BackgroundThe hemodynamics of the cerebral sinuses play a vital role in understanding blood flow‐related diseases, yet the hemodynamics of the cerebral sinuses in normal adults remains an unresolved issue.PurposeTo evaluate hemodynamics in the cerebral sinus of adults using 4‐dimensional flow MRI (4D Flow MRI).Study TypeCross‐sectional.PopulationNinety‐nine healthy volunteers (mean age, 42.88 ± 13.16 years old; females/males, 55/44).Field Strength/Sequence3 T/4D Flow MRI.AssessmentThe blood flow velocity, average blood flow rate (Q), and vortexes at the superior sagittal sinus (SSS), straight sinus (STS), transverse sinus, sigmoid sinus, and jugular bulb of each volunteer were evaluated by two independent neuroradiologists. The relationship between the total cerebral Q and sex and age was also assessed. Twelve volunteers underwent two scans within a month.Statistical TestsThe intraclass correlation coefficient (ICC) evaluated the inter‐observer agreement. Blood flow parameters among volunteers were compared by the independent‐sample t‐test or Mann–Whitney U test. The multiple linear regression equation was used to evaluate the relationship between total cerebral Q and age and sex. P < 0.05 indicated statistical significance.ResultsThe test–retest and interobserver reliability of average velocity and Q were moderate to high (ICC: 0.54–0.99). Cerebral sinus velocity varied by segment and cardiac cycle. The SSS's velocity and Q increased downstream and Q near torcular herophili was 3.5 times that through the STS. The total cerebral Q decreased by 0.06 mL/s per year (β = −0.06 ± 0.013) and was sex‐independent within the group. Vortexes were found in 12.12%, 8.9%, and 59.8% of torcular herophili, transverse‐sigmoid junction, and jugular bulb, respectively, and were related to higher upstream flow.Data ConclusionCerebral sinuses could be measured visually and quantitatively in vivo by 4D Flow MRI, providing a basis for future research on pulsating tinnitus, multiple sclerosis, and other related diseases.Evidence Level2Technical EfficacyStage 1
Novel antiviral discoveries for Japanese encephalitis virus infections through reporter virus‐based high‐throughput screening
Authors: Yin Chunhong , Yang Peipei , Xiao Qingcui , Sun Peng , Zhang Xuekai , Zhao Jiaxuan , Hu Xue , Shan Chao 
Published: January 2024

AbstractJapanese encephalitis (JE) caused by JE virus (JEV), remains a global public health concern. Currently, there is no specific antiviral drug approved for the treatment of JE. While vaccines are available for prevention, they may not cover all at‐risk populations. This underscores the urgent need for prophylaxis and potent anti‐JEV drugs. In this context, a high‐content JEV reporter system expressing Nanoluciferase (Nluc) was developed and utilized for a high‐throughput screening (HTS) of a commercial antiviral library to identify potential JEV drug candidates. Remarkably, this screening process led to the discovery of five drugs with outstanding antiviral activity. Further mechanism of action analysis revealed that cepharanthine, an old clinically approved drug, directly inhibited virus replication by blocking GTP binding to the JEV RNA‐dependent RNA polymerase. Additionally, treatment with cepharanthine in mice models alleviated JEV infection. These findings warrant further investigation into the potential anti‐JEV activity of cepharanthine as a new therapeutic approach for the treatment of JEV infection. The HTS method employed here proves to be an accurate and convenient approach that facilitates the rapid development of antiviral drugs.