bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association Between Frailty and Mortality, Falls and Hospitalisation Among Patients Undergoing Dialysis: A Systematic Review and Meta‐Analysis
Authors: He Wan‐Qiao , Zhang Xiao‐Ming , Zhang Yi‐Zhen , Gai Wei , Wu Xin‐Juan , Tao Yan‐Ling 
Published: February 2025

ABSTRACTAimFrailty is a risk factor for adverse events in older individuals; however, it has not been fully verified in patients undergoing dialysis. Our aim was to verify the association between frailty and adverse outcomes consisting of mortality, falls and hospitalisation among patients undergoing dialysis by a systematic review and meta‐analysis.DesignSystematic review and meta‐analysis.MethodsMultiple internet databases, were searched from the establishment of each database to April 2022, including the PubMed, EMbase, Cochrane, CNKI, WanFang and China Science and Technology Journal (VIP) databases. Cohort studies exploring the association between frailty and adverse outcomes among patients undergoing dialysis were analysed. The Newcastle Ottawa Scale (NOS) was used to assess the risk of bias in the included studies. A random effects model was used to pool the effect size, and comprehensive analyses consisting of subgroup analysis, sensitivity analysis and publication bias were assessed.ResultsThe search initially identified 2744 studies from six databases. After the screening, 26 studies including 14,089 patients with dialysis aged 44.95–78.10 years were included in the final analysis, all of which were observational cohort studies. The pooled results showed that frailty was a powerful predictor of adverse outcomes (mortality, falls and hospitalisation) among the patients. Therefore, dialysis patients should be screened for early frailty and appropriate interventions should be implemented to improve adverse outcomes.
Thinking with Amazonian Indigenous Peoples to expand ideas on domestication
Authors: Cassino Mariana Franco , Henriques Soares Guilherme , Mendes dos Santos Gilton , Gouveia Jonilda Hauwer , Barreto João Paulo Lima , Azevedo Dagoberto Lima , Maia Gabriel Sodré , Lins Juliana , Ramos Clarinda Maria , Shock Myrtle Pearl , Madella Marco , Clement Charles Roland 
Published: February 2025

Abstract

Indigenous knowledges are being increasingly recognized as fundamental for environmental governance, ecosystem management and biodiversity conservation. However, they tend to be recognized by Western science only when they converge with Western scientific knowledge, while ontological differences are generally treated as irrelevant or unreasonable beliefs. Given this scenario, embracing difference as a productive and fundamental aspect to truly understand these epistemologies is crucial to advance fair and symmetrical epistemological dialogues.

Current domestication models are key to interpreting human‐plant‐animal‐landscape entanglements. However, they have been criticized in the Amazonian context for remaining steeped in the Western logic of human control over nature and for neglecting local worldviews, which do not assume a dichotomy between nature and culture. In light of this, we propose a thought‐provoking exercise that aims to broaden ideas on domestication as inspired by Indigenous worldviews. We integrate insights derived from Amazonian Indigenous knowledge systems to construct a conceptual model of domestication. We then engage the synthesis resulting from this approach with concepts and theories from ecology and anthropology.

In our model, plants, animals, supernatural beings and humans care for, manage and cultivate their domains. Since, according to Indigenous ontologies, all these beings have agency, intentionality, and human qualities, they all share the status of domesticators in our model. The outcome of the combined actions of these beings is an entirely socialized forest, formed by a mosaic of domūs of both humans and non‐humans. Thus, in our model, the forest is fully domesticated by the action of a multiplicity of beings, who possess symmetrical agencies and are constantly interacting socially.

By following the reflective path constructed in our approach, we invite the reader to ‘think with’ Indigenous Peoples. Instigated by this framework, we suggest directions to broaden conventional ecological approaches used for studying socio‐ecological systems and promote conservation. We hope to inspire the creativity of current ecological research dynamics to design investigations that go beyond the anthropocentric perspective and the nature/culture dichotomy.

Read the free Plain Language Summary for this article on the Journal blog.
Hydroxyurea Therapy and Sleep‐Disordered Breathing in Children With Sickle Cell Disease
Authors: Abramson Zachary , Olanrewaju Ayobami , Kang Guolian , Olufadi Yunusa , Chen Pei‐Lin , Rai Parul , Heitzer Andrew M. , Takemoto Clifford M. , Bashir Ahsan , Akil Nour , Hankins Jane S. 
Published: February 2025

ABSTRACTBidirectional relationships exist among sickle cell disease (SCD), sleep‐disordered breathing (SDB), and hydroxyurea therapy, and this complex interplay poses challenges to research attempting to elucidate causal mechanisms and determine therapeutic targets. We therefore set out to study all three components of this clinical triad simultaneously (SCD, SDB, and hydroxyurea therapy), documenting correlations and suggesting underlying pathophysiological mechanisms. Hydroxyurea therapy was associated with improved SDB and with decreased inflammation, implicating the anti‐inflammation effects of hydroxyurea as a plausible mechanism driving these correlations. These results underscore the need for longitudinal studies to elucidate causal relationships.
Shared Priorities for Sibling Psychosocial Support in Pediatric Cancer Care: A Value‐Weighting Study
Authors: Davis Kathryn A. , Lai Samuel , Alderfer Melissa A. , Long Kristin A. 
Published: February 2025

ABSTRACTBackgroundAlthough psychosocial support for siblings of youth with cancer is a standard of care, what sibling supportive services should entail remains unclear. Given limited resources for sibling care, establishing clinical and research priorities may guide resource allocation toward supports perceived as holding the greatest potential benefit. The current study used a two‐round, value‐weighting approach to identify priorities for sibling support services.ProcedureParticipants were recruited from a group of sibling experts (clinicians, researchers, community program leaders, and adults who had a sibling with childhood cancer) invited to attend an international sibling summit. In Round 1, 27 participants provided feedback on a list of potential priorities for sibling psychosocial support. In Round 2, 30 participants completed a web‐based value‐weighting questionnaire indicating how they would allocate 100 units of hypothetical funding among various priorities and qualitatively described the rationale for their decisions.ResultsFunding allocations generally averaged out across participants, highlighting the need for investments across all domains of sibling support. Participants allocated the greatest proportion of hypothetical funding to community‐based sibling supports, which they perceived as more accessible to siblings than hospital‐based supports. Participants allocated a particularly high level of funding to sibling supports in local schools. Within sibling subpopulations, bereaved siblings, siblings during active cancer treatment, and siblings with more adverse social determinants of health were allocated the largest proportion of funds.ConclusionsSibling‐focused researchers, clinicians, program leaders, and adult siblings endorse broad investments in sibling support. Investments in community‐based supports particularly may improve access to sibling support services.
Sandwich‐structured light‐transmitting composites based on waste textiles: Fabrication, optical properties, and bending failure behavior
Authors: Ren Tianxiang , Fang Taorong , Xu Yudong , Zhan Haihua , Chen Lifeng , Shen Wei , Zhao Defang , Shao Yuanyi , Zhang Xiaolin 
Published: February 2025

AbstractCurrently, glass fiber‐reinforced resin composites, as an advanced optically transparent material, have garnered widespread attention and research. In the context of new‐era developments, there is a growing demand and expectation for the visual artistic expression of light‐transmitting composites. In this study, glass fiber fabric, silk fabric, and recycled polyester jacquard fabric were used as reinforcement materials, while epoxy resin was selected as the matrix material. A green decorative light‐transmitting composite with uniform light diffusion and soft light effects was prepared using the vacuum bag molding process. By altering the woven structure (plain weave, twill weave, satin weave), yarn density, and yarn twist of the silk fabric, the optical properties of the composites can be regulated. The unique triangular cross‐section, woven structure, and large folds of the plain‐woven silk fabric were particularly conducive to the reflection and refraction of light within the composite, thereby significantly enhancing the uniform light diffusion and soft light properties of the material. Furthermore, the bending failure behavior of the composites was investigated through three‐point bending tests, acoustic emission (AE) test, and micro‐computed tomography (Micro‐CT) scanning. The laminate specimens reinforced with plain‐woven silk fabric exhibited the best bending performance, with bending strength and modulus reaching 434.4 MPa and 19.0 GPa, respectively. The combination of AE and micro‐CT scanning techniques successfully established the correlation between AE signals and damage modes. This study identified the main failure modes for plain woven, twill woven, and satin woven silk reinforced composites as fiber breakage, interlayer delamination, and fiber/resin debonding, respectively.Highlights
Waste textiles were recycled for use in transparent composites.
Silk fabric's weave structure affected composites' optical properties.
Fiber breakage was the main failure in bending of plain woven composites.
Plain woven composites exhibited optimal diffuse light, superior flexural performance.
Remifentanil Ameliorates Lipopolysaccharide‐Induced Neuroinflammation by Regulating the Phosphatidylinositol 3‐Kinase/Serine–Threonine Protein Kinase/Hypoxia‐Inducible Factor 1 Alpha Pathway
Authors: Özcan Mustafa Soner , Aşcı Halil , Karabacak Pınar , Özden Eyyüp Sabri , İmeci Orhan Berk , Özmen Özlem 
Published: February 2025

ABSTRACTThere has been scarce research on the potential neuroprotective effects of remifentanil (REM) in septic individuals. We aimed to investigate the role and underlying mechanism of REM in LPS‐induced neuroinflammation. Thirty‐two rats were randomly divided to control, lipopolysaccharide (LPS), LPS + REM, and REM groups. Depending on the group, 4 h after intraperitoneal administration of LPS or saline, REM or saline was infused intravenously for 40 min. Following the sacrification, blood samples and brain tissues were collected for analysis. Brain tissues (prefrontal cortex, cerebellum, and hippocampus) were stained with hematoxylin and eosin, caspase‐3 (Cas‐3), and tumor necrosis factor alpha (TNF‐α). Quantitative reverse transcription‐polymerase chain reaction analysis was used to detect claudin‐5 (CLDN5), zonula occludens‐1 (ZO‐1), phosphatidylinositol 3‐kinase (PI3K), serine–threonine protein kinase (AKT), and hypoxia‐inducible factor 1 alpha (HIF‐1α) gene expression levels. Histopathologic and immunohistochemical analyses showed that REM treatment improved LPS‐induced histological changes. REM does not reduce TOS and OSI levels or increase TAS levels, suggesting that it is ineffective through oxidative stress. LPS‐induced changes in gene expression levels (PI3K, AKT, HIF‐1α, and CLDN5) were also reversed by REM. REM was found to prevent neuroinflammation, and apoptosis by restoring blood–brain barrier, and regulating the PI3K/AKT/HIF‐1α pathway. These findings suggest that REM is protective against neuroinflammation.
Characterization and functional analysis of Spodoptera litura galectins
Authors: Zhong Jielai , Li Jin , Wu Denghui , Deng Xinyue , Lu Yuzhen , Yu Xiao‐Qiang 
Published: February 2025

AbstractBACKGROUNDInsects rely on their effective innate immune system to defend against pathogen infection, and pattern recognition receptors (PRRs) play a crucial role in insect immunity. Galectins, a family of animal β‐galactoside‐binding lectins, may serve as PRRs. Mammalian galectins are involved in diverse physiological processes; however, less is known about functions of insect galectins.RESULTIn this study, we focused on an agricultural pest Spodoptera litura and identified a total of 13 Slgalectins, and a functional study of Slgalectin‐4 and Slgalectin‐7 was conducted. Both recombinant Slgalectin‐4 and Slgalectin‐7 proteins directly bound to Bacillus thuringiensis and an entomopathogenic fungus Metarhizium rileyi. Importantly, supplementing recombinant Slgalectin‐4 to S. litura larvae significantly increased larval survival after M. rileyi infection but accelerated larvae death after B. thuringiensis infection, whereas supplementing Slgalectin‐7 increased larval survival after B. thuringiensis infection but did not influence larval survival after M. rileyi infection. Supplementing both Slgalectin‐4 and Slgalectin‐7 altered the expression of some antimicrobial peptide genes in larval hemocytes after microbial infection, which may partly account for the roles of Slgalectin‐4 and ‐7 in larval survival.CONCLUSIONOur findings revealed that Slgalectin‐4 and ‐7 may serve as PRRs to bind different pathogens and alter expression of immune effector genes such as antimicrobial peptide genes, eventually modulating immune responses of S. litura larvae to pathogens such as B. thuringiensis and M. rileyi. © 2025 Society of Chemical Industry.
Pyrolysis Kinetics of Polytetrafluoroethylene (PTFE)
Authors: Wang Yongjin , Wang Shengkai , Chu Qingzhao , Chen Dongping 
Published: February 2025

ABSTRACTPolytetrafluoroethylene (PTFE) is widely used in fields such as propellants and flame retardants. However, this is still a vacancy of detailed kinetic mechanisms to describe the complete decomposition of PTFE in the gas phase. The current work addresses this issue by conducting ab initio calculations for key reactions involved in the PTFE pyrolysis system. The potential energy surfaces (PESs) of PTFE unimolecular and bimolecular reactions are determined at the DLPNO‐CCSD(T)/cc‐pVTZ//B3LYP‐D3/6–31++G(d,p) level. Rate constants and branching ratios of the main reaction pathways are calculated by solving the RRKM master equation, and the thermochemical properties of related species at the DLPNO‐CCSD(T)/CBS level are calculated via the atomization method. The current study found that the initial decomposition of PTFE is dominated by the CC scission reactions and free radical (H, OH, CF, CF2, and CF3) abstraction reactions, forming the corresponding free radical species. Further β‐CC scission reactions dominate the overall kinetics and continuously generate CF2CF2. Self‐decomposition and free radical–driven decomposition of PTFE produce small molecules such as HF, FOH, CF2, CF3, and CF4. This work provides quantitative predictions of the detailed decomposition reaction pathways of gas‐phase PTFE and will lay a solid foundation for the development of detailed kinetic mechanisms for PTFE combustion and degradation.
Extrinsic Pseudocapacitive CoOOH Achieved by the Suppression of Its Phase Transition Triggered by S2− Doping
Authors: Qi Lizhuo , Li Jing , Liu Yuanyuan , Liu Kaihua , Wang Meiri , Cui Hongtao 
Published: February 2025

AbstractThe behavior transformation of battery‐type materials to extrinsic pseudocapacitive behavior is accomplished by suppressing their phase transition. The resulting extrinsic pseudocapacitive materials are a valuable supplement to intrinsic pseudocapacitive materials, enriching the connotation of pseudocapacitive materials. Nevertheless, the research on this category of materials remains inactive as of now, probably due to the as yet unclear phase transition suppression mechanism and the associated electrochemical mechanism. In this work, the battery‐type Co(OH)2 is selected as a research object to create an extrinsic pseudocapacitive material by S2− doping. It is revealed that the K+ intercalation/deintercalation is the essential reason for the phase transition of CoOOH that is irreversibly converted from Co(OH)2, leading to its battery‐type behavior. Whereas, the fully protonated CoOOH produced due to the high reaction activity of S2− doped Co(OH)2 only allows the intercalation/deintercalation of H+. During the process of intercalation/deintercalation of H+, CoOOH retains the P3 structure, thereby giving rise to extrinsic pseudocapacitive behavior. The electrochemical measurement results indicate that this extrinsic pseudocapacitive material and the assembled device have electrochemical performance equivalent to that of intrinsic pseudocapacitive materials.
Low‐Concentration Flame‐Retardant PC‐Based Electrolytes for Wide‐Temperature and High‐Voltage Lithium‐Ion Batteries
Authors: Xu Tonghui , Luo Shengyao , Wu Mengqi , Amzil Said , Ru Zhengzheng , Yue Ye , Xiao Yiyao , Peng Meilan , Li Yinghui , Zuo Xiuxia , Gao Jie , Yu Ying , Zheng Tianle , Zhao Hongbin , Cheng Ya‐Jun , Xia Yonggao 
Published: February 2025

AbstractPropylene carbonate (PC) is regarded as a promising solvent for replacing ethylene carbonate due to its high dielectric constant and wide working temperature range. However, the co‐intercalation behavior between PC and Li+ on graphite poses limitations to its further application. In this study, a weakly solvating solvent of methyl trifluoromethyl carbonate (FEMC) and lithium bis(oxalato)difluorophosphate (LiDODFP) synergistically enable reversible cycling of low‐concentration PC‐based electrolytes on graphite. Nuclear magnetic resonance spectroscopy and theoretical calculations indicate that FEMC partially substitutes PC in the solvation structure and interacts with PC through intermolecular forces, facilitating desolvation of Li+. Moreover, the utilization of LiDODFP enhances the solvation structure of Li+, effectively resolving the compatibility issue between graphite and PC. This electrolyte exhibits exceptional oxidative stability and nonflammability properties. At a cut‐off voltage of 4.5 V, the NCM811/graphite full cell exhibits 88.86% capacity retention after 300 cycles at 25 °C, and retains 76.23% capacity after 100 cycles at 60 °C; even at −40 °C, it still delivers a capacity of 67 mAh g−1. This work presents a novel strategy for developing low‐concentration, wide‐temperature‐applicable, high‐safety, and high‐voltage PC‐based electrolytes.
Counter Ions Determine Self‐Assembled Nanostructure and Activation Energy of Ion‐Conductive Mesogens
Authors: Rim Minwoo , Kim Woojin , Kang Dong‐Gue , Pham Huu Huan , Wi Youngjae , Oh Mintaek , Ko Hyeyoon , De Sio Luciano , Kim Dae‐Yoon , Jeong Kwang‐Un 
Published: February 2025

AbstractBy varying counter ions of ion‐conductive mesogens (ICMs) from bromide (Br), to tetrafluoroborate (BF4), and to bis(trifluoromethanesulfonyl)imide (TFSI), the ionic conductivity of ICM is systematically investigated based on their self‐assembled nanostructure and activation energy. Thermal and phase transition behaviors of ICM‐Br, ‐BF4, and ‐TFSI exhibit significant variation based on the anion type. These differences are further reflected in the self‐assembled nanostructures of the ICMs, which are characterized through X‐ray and electron diffraction experiments. Ionic conductivity measured by electrochemical impedance spectroscopy and activation energy calculated by Arrhenius equation allow us to build the relationship between self‐assembled nanostructures of ICMs and their activation energy. The constructed relationship between self‐assembled nanostructures and activation energy can provide valuable insights for the development of novel ion‐conductive materials.
Room‐Temperature Synthesis of Amorphous Fe‐Doped Nickel Phosphate for High‐Efficiency Alkaline Seawater Oxidation
Authors: Xu Deshuang , Zhang Chenxi , Liu Yun , Ye Qing , Lu Jinjun , Zhao Yanxia , Ma Jiani , Cheng Yongliang 
Published: February 2025

AbstractThe construction of an efficient and durable oxygen evolution reaction (OER) electrocatalyst through a simple synthesis strategy is crucial for the hydrogen produced from seawater splitting. However, achieving this goal remains a great challenge. Herein, the synthesis of amorphous Fe‐doped nickel phosphate (Fe‐NixPO4) as a high‐performance OER electrocatalysts for alkaline freshwater/seawater splitting is presented using a straightforward co‐precipitation method at room‐temperature. Experimental results reveal the structural reconstruction of Fe‐NixPO4 into Fe‐doped NiOOH decorated with PO43−. The collaborative interplay between Ni2+ and Fe3+, along with the decoration of PO43−, can effectively modulate the electronic environment of the electrocatalyst. Consequently, the optimized Fe‐NixPO4 exhibits exceptional OER activity, requiring overpotentials of 359 and 422 mV to generate 1000 mA cm−2 in alkaline freshwater and alkaline seawater, respectively. Moreover, Fe‐NixPO4 also displays outstanding stability for 100 h at 100 mA cm−2 in alkaline seawater. This research presents a viable approach for fabricating OER electrocatalysts with exceptional efficiency for seawater electrolysis.
All‐Inorganic Lead‐Free Cs₂AgBiBr₆/ZnO Artificial Retina Synapse Based on Photoelectric Synergistic Dual‐Mechanism for Neuromorphic Computing
Authors: Cheng Zhenpeng , Wang Tianle , Zhu Junyan , He Yaqi , Liu Shijie , Li Ming‐Yu , Lu Haifei , Wen Xiaoyan , Lee Jihoon , Liu Sisi , Mao Sui 
Published: February 2025

AbstractAdaptive learning capability of optoelectronic synaptic hardware holds promising application prospects in next generation artificial intelligence, and the development of biometric retina perception is sternly hampered by three crucial issues, including well‐balance between excitatory and inhibitory, non‐volatile multi‐state storage, and optimal energy consumption. In this work, a novel Cs2AgBiBr6/ZnO non‐volatile optoelectronic synapse is proposed and successfully programmed with optical excitatory and electronic inhibitory in the light of dual‐mechanism: Lead‐free perovskite Cs2AgBiBr6 guarantees abundant photogenerated carrier concentration, and the process of carrier capture and release occurs in ZnO layer, which can collaboratively modulate various synaptic plasticity behaviors depending on distinct stimulus. Consequently, multi‐bit storage is attained with the dual‐mechanism non‐volatile memory (DNVM) as a function of consecutive light spikes. The energy consumption of the DNVM is 1.85 nJ at a single light spike, and an ultra‐low one of 13.8 fJ is triggered with a single electrical pulse, which approximatively meets the requirement of the biological synaptic event energy consumption. The performance of the DNVM is further evaluated with the Pavlov's classical conditioning experiment and visual hardware system, offering an exciting paradigm for implementing on‐chip adaptive visual perception and neuromorphic computing.