bluuebunny/crossref_metadata_2025_split huggingface dataset:
A meta-analysis of the efficacy and safety of the traditional Chinese medicine formula Kaixinsan decoction for depression
Authors: Li Jia-liang , Lin Lin , Wu Min-min , Zhang Jing-yu , Zhang Yi-xin , Cao Meng-ru , Wang Long 
Published: January 2024

Background:
Kaixinsan (KXS) decoction is a traditional Chinese herbal formulation commonly used to treat depression. This study aimed to evaluate the efficacy and safety of KXS, which is widely used, alone and in combination with other therapies, for the treatment of depression. The main objective was to assess the efficacy and safety of KXS in the treatment of depression as a single agent or in combination with other methods.

Methods:
Randomized controlled trials of KXS in the treatment of depression were systematically searched from several Chinese and English databases with no language restriction. Patients in these studies met the relevant diagnostic criteria for depression. Data on HAMD, SDS, practical situations, and occurrence of side effects in the studies were extracted. Finally, the methodological quality and risk of bias of the included studies were assessed using the Jadad scale and Cochrane bias evaluation tool.

Results:
Twelve studies with 1034 patients were included after screening. The Jadad scale and Cochrane bias evaluation tool indicated that the quality of the studies ranged from fair to good, with 41.7% categorized as good and 58.3% as poor. Egger test and funnel plots showed that the publication bias remain low.

Conclusion:
The results showed that the frequency of side effects in the control group was higher than that in the treatment group, and there was a statistically significant difference. KXS was comparable or superior to antidepressants in treating depression and has fewer side effects. The data analysis showed that effectiveness and other indicators differed significantly by geographic area and dosage form, which has implications for future clinical work.
The Brunner adenoma of the duodenum with positive fecal occult blood and anemia: A case report
Authors: Duan Junwei , Wang Xiaoyan , Xu Chenxi , Guo Rongxin 
Published: January 2024

Rationale:
Brunner gland adenoma (BGA) is a rare benign duodenal tumor that is an adenomatoid lesion in nature rather than an actual tumor. Patients with different adenoma sizes have various clinical manifestations with nonspecific clinical symptoms. Here, We report a case of BGA with black stool and anemia as the primary manifestations.

Patient concerns:
A young female patient was admitted to the hospital because of black stool and anemia. Endoscopic surgery was performed to a definitive diagnosis, and endoscopic tumor-like lesions were resected.

Diagnosis:
The patient was diagnosed with duodenal Brunner adenoma and received related treatment.

Outcomes:
After treatment, the patient symptoms improved, and he was discharged.

Lessons:
Brunner adenoma of the duodenum is a rare benign duodenum tumor. This report paper describes a case of BGA with black stool and anemia as the primary manifestations, followed by endoscopic resection and treatment. The literature on Brunner adenoma of the duodenum has been analyzed and discussed. Clinicians should pay attention to differentiating the disease based on atypical symptoms.
The effects of mobile technology-based support on young women with depressive symptoms: A block randomized controlled trial
Authors: Jeong Sookyung , Cha Chiyoung , Nam Sujin , Song Jiyoon 
Published: January 2024

Background:
The current body of knowledge highlights the potential role of mobile technology as a medium to deliver support for psychological and physical health. This study evaluated the influence of mobile technology support on depressive symptoms and physical activity in female university students.

Methods:
A block randomized controlled trial design with a single site was used. Ninety-nine participants were block-randomized into 3 arms: Experimental Group 1 (emotional and informational support group), Experimental Group 2 (informational support group), and the control group. Interventions were delivered via mobile technology for 2 weeks. Data on depressive symptoms and physical activity were collected from 84 participants at baseline and on Days 8 and 15. Data analyses included descriptive statistics, t tests, one-way analysis of variance, and repeated-measures analysis of variance.

Results:
This study showed no interaction effect of time and group on depressive symptom scores and physical activity, considering the emotional and informational support from mobile technology. However, Experimental Group 1 exhibited a significant reduction in depressive symptoms during the first week of the study compared to Experimental Group 2 and the control group. While physical activity in Experimental Group 2 and control group increased only during the first week of the study and subsequently decreased, Experimental Group 1 showed an initial increase during the first week that was sustained into the second week.

Conclusions:
Since informational and emotional support showed a strong effect over a short period of time, mobile technology offering emotional support could be used to provide crisis interventions for depression among young women when a short-term impact is required.
Visual analysis of obesity and hypothyroidism: A bibliometric analysis
Authors: Yao Lanying , Zhang Long , Tai Yuxing , Jiang Rongsheng , Cui Jianzhong , Gang Xiaochao , Liu Mingjun 
Published: January 2024

Background:
The prevalence of obesity is gradually increasing and is closely associated with hypothyroidism. It is of research interest to explore the association between obesity and hypothyroidism and the current status of research.

Methods:
We chose the Web of Science Core Collection (WoSCC) database as the data source and searched to obtain relevant literature on obesity and hypothyroidism. And we used CiteSpace and VOSviewer to analyze the related literature.

Results:
A total of 508 articles were included in the literature, with an overall increasing trend in the number of publications. There were 170 relevant countries or organizations, and the United States was the country with the most publications. There were 1742 related organizations, and the Egyptian Knowledge Bank (EKB) was the organization with the most publications. There are 3015 authors involved, and there is a clear collaboration between authors. There are 227 related journals and J CLIN ENDOCR METAB is the most cited journal. The most frequently occurring keywords were obesity and hypothyroidism, but also other related topics such as bariatric surgery, metabolic syndrome, insulin resistance, body mass index, and leptin.

Conclusion:
The research related to obesity and hypothyroidism is gradually gaining attention, and the research direction is gradually expanding to metabolic syndrome, insulin resistance, leptin, and other related topics.
Use of telemedicine to tackle health problems in South Asia during the COVID-19 era and beyond: a systematic review
Authors: Saleem Muhammad K. , Sattar Komal , Ejaz Khawaja F. , Rehman Muneeb U. , Saleem Humayun , Khursheed Soffia , Akbar Amna , Ahmed Jahanzeb , Tariq Maham , Jadoon Sarosh K. , Saleem Khan Mohammad , Tasneem Sabahat , Khandker Shahad S. , Kundu Shoumik , Alvi Sarosh 
Published: January 2024

Introduction:Telemedicine (TM) and teleconsultation services flourished during coronavirus disease 2019 (COVID-19) transmission to avoid COVID-19 infection and physical contact. Many physicians switched to the virtual treatment mode and nearly all types of health disciplines were covered. Through this systematic review, the authors tried to explore the strengths and weaknesses of TM, identify the barriers to adopting TM by population, and explain the limitations of this healthcare delivery model.Methods and results:In this systematic review, 28 studies were included (>53% high-quality studies) as eligible, where nearly 75% (n=21) of the studies were from India, and the remaining 25% (n=7) were from Pakistan, Bangladesh, Sri Lanka, and Nepal. Advice related to cancer, autoimmune diseases, and neurological diseases were the most common among the health disciplines in which TM was used. A peak in teleconsultation was observed during the high transmission phase of COVID-19, although major queries were associated with existing health complications and comorbidities.Conclusion:Other than a few concerns regarding connectivity, privacy, and diagnosis, TM was in fact affordable, timesaving, feasible, and accurate, which ensured a highly satisfying experience among the participants (>80%).
Patient Experiences and Perceptions of Care Coordination in Primary Care
Authors: Whitebird Robin R. , Solberg Leif I. , JaKa Meghan M. , Kindt Joan M. , Bergdall Anna , Beran Mary Sue , Winger Melissa 
Published: January 2024

Background:
Understanding patient perceptions of care coordination in primary care can help improve responsiveness to patients' needs, outcomes, and quality of care.

Purpose:
The purpose of this study was to explore patient experiences and perceptions of care coordination in primary care.

Method:
Interviews with 13 patients from 10 clinics were conducted and analyzed using directed content analysis.

Results:
Three primary themes arose: care coordinators provide a gateway to accessing needed care; patients needed and valued the support and trusted advice of their care coordinators; and patients valued care coordinators' help with navigating, engaging, and educating them about their care.

Conclusions:
Understanding what patients value in care delivery can help frame a vision for a more responsive approach in delivering primary care, as well as create a pathway to quality improvement, moving toward a truly patient-centered focus in primary care.
Evaluating the Efficiency of Survey Collection Methods to Trauma Patients
Authors: Moran Vicki , Oberle Andrew , Israel Heidi 
Published: January 2024

Background:
Traumatic injury survivors often experience negative health consequences, impacting recovery. No studies have assessed the feasibility of evaluating the resiliency of hospitalized trauma patients using the 10-item Connor-Davidson Resilience Scale (CD-RISC-10).

Purpose:
The purpose of this study was to determine the most efficient method to collect survey responses on the CD-RISC-10.

Methods:
This cross-sectional study used a convenience sample of admitted patients with traumatic injury. Patients were randomized to complete the CD-RISC-10 using pen and paper, tablet, or workstation on wheels.

Results:
Of the 161 patient surveys, the tablet-based survey took the shortest time to complete (2 minutes, 21 seconds), and the paper survey resulted in the lowest percentage of missed questions (0.5%). Trauma patients reported high levels of resiliency.

Conclusion:
The CD-RISC-10 can be easily administered to trauma patients. Clinicians should balance efficiency and patient preferences when deciding on a survey collection method.
Parallel Osteotome Technique: New Approach to Reduce Neurosensory Disturbances following Bilateral Sagittal Split Osteotomy
Authors: Parameswaran Anantanarayanan , Panneerselvam Elavenil 
Published: January 2024

Background:
The purpose of this study was to determine clinically whether the parallel osteotome technique (POST) reduces the incidence of neurosensory disturbances (NSDs) following bilateral sagittal split osteotomy (BSSO), and to corroborate the findings with finite element analysis.

Methods:
The authors conducted a quasiexperimental study of 30 patients requiring BSSO. The sample was divided into two groups: a control group who underwent the conventional osteotomy technique and an experimental group who underwent POST osteotomy. A finite element analysis simulation of the two techniques was also generated for computational analysis. The primary outcome was clinical comparison of subjective and objective measures for NSDs; the secondary outcome was a comparison of stress, strain, and deformation. The osteotomy technique was the exposure studied. Data were analyzed for differences in proportions and means.

Results:
Thirty patients (12 female and 18 male patients; age range, 18 to 28 years; mean age, 21.6 years) were recruited for the study, providing 60 sides as a sample. The experimental group had significantly lower subjective scores for NSD at the 3-month (P = 0.03) and 6-month follow-ups (P = 0.025). Objective testing revealed a lower incidence of NSDs for the experimental group during postoperative months 3 (P = 0.07), 6 (P = 0.007), and 12 (P = 0.17). The computational analysis also revealed significantly lower stress (P = 0.007), strain (P = 0.009), and deformation (P = 0.04) on the inferior alveolar nerve with the POST osteotomy.

Conclusions:
The incidence of NSDs following BSSO is lower with the POST osteotomy. This technique also induced significantly lower deformational forces on the inferior alveolar nerve when compared with the conventional osteotomy.
The disease burden of respiratory syncytial virus in older adults
Authors: Kenmoe Sebastien , Nair Harish 
Published: January 2024

Purpose of review
To highlight the respiratory syncytial virus (RSV) disease burden and the current developments and challenges in RSV prevention for older adults ≥60 years through analysis of RSV epidemiology and the effectiveness of emerging vaccines.

Recent findings
In industrialized countries, RSV incidence rates and hospitalization rates among older adults are estimated to be 600.7 cases per 100 000 person-years and 157 hospitalizations per 100 000 person-years, respectively. Yet, accurately determining RSV morbidity and mortality in older adults is challenging, thus resulting in substantially under-estimating the disease burden. The in-hospital fatality rates vary substantially with age and geographies, and can be as high as 9.1% in developing countries. Two promising RSV vaccines for the elderly have been approved, demonstrating efficacies of up to 94.1%, signifying considerable advancement in RSV prevention. However, concerns over potential side effects remain.

Summary
RSV is associated with a significant burden in older adults. While the landscape of RSV prevention in older adults is promising with the licensure of vaccines from two companies, current trial data underscore the need for additional studies. Addressing the real-world effectiveness of these vaccines, understanding potential rare side effects, and ensuring broad inclusivity in future trials are crucial steps to maximize their potential benefits.
Veterinary High-Stakes Immersive Simulation Training With Repeat Practice Following Structured Debriefing Improves Students' Ability to Cope With High-Pressure Situations
Authors: Pollock Kristina , MacKay Jill R.D. , Hearns Stephen , Morton Carolyn , Pollock Patrick John 
Published: January 2024

Introduction
Immersive simulation is used increasingly in medical education, and there is increasing awareness of the impact of simulation scenarios on emotional state and cognitive load and how these impact learning.
1
There is growing awareness of the requirement to equip veterinarians with skills for managing high-pressure environments and provide training on human factors.

Methods
Veterinary students participated in a high-fidelity immersive simulation of a road traffic collision involving multiple casualties. The students took part in the same simulation twice, the second time after a debrief. Each participant's emotional state and cognitive load were assessed after participating in each simulation. Each participant was asked to score the effect of pressure on their performance.

Results
One hundred twenty-five students participated and demonstrated a higher cognitive load with more positive emotional states during the second scenario after the completion of a structured debrief and discussion focusing on pressure relief techniques (cognitive load - ¯μ Scenario run 1 = 4.44 ± 1.85 [SD], ¯μ Scenario2 = 5.69 ± 1.74 [SD]). Most (63%) participants described being in a low-performance state of frazzle during the first scenario compared with most (61%) who described being in a high-performance state of flow during the second.

Conclusion
Immersive simulation scenarios, with structured debriefing, may allow the measurement of emotional state and cognitive load in participants. Furthermore, this study suggests that curriculum training in human factors and pressure relief techniques, coupled with immersive simulation and debrief, may improve future performance in high-stakes and high-pressure scenarios.
Trauma surgeons experience compassion fatigue: A major metropolitan area survey
Authors: Hoefer Lea , Tatebe Leah C. , Patel Purvi , Tyson Anna , Kingsley Samuel , Chang Grace , Kaminsky Matt , Doherty James , Hampton David 
Published: January 2024

INTRODUCTION
Compassion fatigue (CF), the physical, emotional, and psychological impact of helping others, is composed of three domains: compassion satisfaction (CS), secondary traumatic stress (STS), and burnout (BO). Trauma surgeons (TSs) experience work-related stress resulting in high rates of CF, which can manifest as physical and psychological disorders. We hypothesized that TSs experience CF and there are potentially modifiable systemic factors to mitigate its symptoms.

METHODS
All TSs in a major metropolitan area were eligible. Personal and professional demographic information was obtained. Each participant completed six validated surveys: (1) Professional Quality of Life scale, (2) Perceived Stress Scale, (3) Multidimensional Scale of Perceived Social Support, (4) Adverse Childhood Events Questionnaire, (5) Brief Coping Inventory, and (6) Toronto Empathy Questionnaire. Compassion fatigue subscale risk scores (low, <23; moderate, 23–41; high, >41) were recorded. Linear regression analysis assessed the demographic and environmental factors association with BO, STS, and CS. Variables significant on univariate analysis were included in multivariate models to determine the independent influence on BO, STS, and CS. Significance was p ≤ 0.05.

RESULTS
There were 57 TSs (response rate, 75.4% [n = 43]; White, 65% [n = 28]; male, 67% [n = 29]). Trauma surgeons experienced CF (BO, 26 [interquartile range (IQR), 21–32]; STS, 23 [IQR, 19–32]; CS, 39 [IQR, 34–45]). The Perceived Stress Scale score was significantly associated with increased BO (coefficient [coef.], 0.52; 95% confidence interval [CI], 0.28–0.77) and STS (coef., 0.44; 95% CI, 0.15–0.73), and decreased CS (coef., −0.51; 95% CI, −0.80 to −0.23) (p < 0.01). Night shifts were associated with higher BO (coef., 1.55; 95% CI, 0.07–3.03; p = 0.05); conversely, day shifts were associated with higher STS (coef., 1.94; 95% CI, 0.32–3.56; p = 0.03). Higher Toronto Empathy Questionnaire scores were associated with greater CS (coef., 0.33; 95% CI, 0.12–0.55; p < 0.01).

CONCLUSION
Trauma surgeons experience moderate BO and STS associated with modifiable system- and work-related stressors. Efforts to reduce CF should focus on addressing sources of workplace stress and promoting empathic care.

LEVEL OF EVIDENCE
Prognostic and Epidemiological; Level III.
Trends and variation in cervical spine imaging utilization across children's hospitals for pediatric trauma
Authors: Ross Erin E. , Ourshalimian Shadassa , Spurrier Ryan G. , Chaudhari Pradip P. 
Published: January 2024

BACKGROUND
Cervical spine (c-spine) evaluation is a critical component in trauma evaluation, and although several pediatric c-spine evaluation algorithms have been developed, none have been widely implemented. Here, we assess rates of c-spine imaging use across children's hospitals, specifically temporal trends in imaging use, variation across hospitals in imaging used, and timing of magnetic resonance imaging in admitted patients.

METHODS
Data from the Children's Hospital Associations Pediatric Health Information System were abstracted from 2015 to 2020. Patients younger than 18 years seen in the emergency department with an International Classification of Diseases, Tenth Revision, code indicative of trauma and c-spine plain radiograph or computed tomography (CT) in the emergency department were included. Data visualization and descriptive statistics were used to assess rates of imaging use by age, year, hospital, injury severity, and day of service. Changes in rates of imaging use over time were evaluated via simple linear regression.

RESULTS
Across 25,238 patient encounters at 35 children's hospitals, there was an increase in use of c-spine CT from 2015 to 2020 (28.5–36.5%). There was substantial interinstitutional variation in rates of use of plain radiographs versus CT for initial evaluation of the c-spine across all age groups. Magnetic resonance imaging was obtained more than 3 days after admission in 31.5% of intensive care patients who received this imaging.

CONCLUSION
Increasing use of CT, substantial interinstitutional variation in rates of use of plain radiographs versus CT, and heterogenous timing of magnetic resonance imaging for evaluation of the pediatric c-spine demonstrate the growing need for development and implementation of an age-specific c-spine evaluation algorithm to guide judicious use of diagnostic resources.

LEVEL OF EVIDENCE
Prognostic and Epidemiological; Level III.
Decompressive craniectomy versus craniotomy for acute subdural hematoma: Updated meta-analysis of real-world clinical outcome after RESCUE-ASDH trial
Authors: Chang Yu , Wong Chia-En , Perng Pang-Shuo , Atwan Hany , Chi Kuan-Yu , Lee Jung-Shun , Wang Liang-Chao , Huang Chih-Yuan 
Published: January 2024

INTRODUCTION
The Randomized Evaluation of Surgery with Craniectomy for Patients Undergoing Evacuation of Acute Subdural Hematoma trial found that disability and quality-of-life outcomes were similar between craniotomy and decompressive craniectomy for traumatic acute subdural hematoma (ASDH), contrasting previous literature. This meta-analysis aimed to validate the applicability of RESCUE-ASDH results using real-world data in ASDH patients.

METHODS
We searched Chocrane, Embase, and MEDLINE for relevant articles reporting clinical outcomes of craniotomy and decompressive craniectomy. Meta-analysis used R software (Ross Ihaka and Robert Gentleman at the University of Auckland, New Zealand) with the restricted maximum likelihood method for random-effects meta-analyses, presenting odds ratios (ORs) and 95% confidence intervals (CIs) with Hartung-Knapp-Sidik-Jonkman adjustment for heterogeneity.

RESULTS
Besides RESCUE-ASDH, five retrospective studies were included, spanning 2006 to 2016. A total of 961 patients with traumatic ASDH were included in this study (craniotomy, 467; decompressive craniotomy, 494). The pooled analysis of retrospective studies showed no significant difference in poor clinical outcomes between the two groups (OR, 0.59; 95% CI, 0.32–1.10). These findings align with the RESCUE-ASDH trial (OR, 0.84; 95% CI, 0.58–1.23). Mortality rate was significantly higher in patients undergoing craniectomy in pooled result of retrospective studies (OR, 0.59; 95% CI, 0.32–1.10). In RESCUE-ASDH trial, reoperation rate was higher in the craniotomy group, but the pooled result of retrospective did not show significant difference between the craniotomy and craniectomy group.

CONCLUSION
This real-world evidence confirms the RESCUE-ASDH trial results. Both craniotomy and decompressive craniectomy yielded similar disability and quality-of-life outcomes for traumatic ASDH patients.

LEVEL OF EVIDENCE
Systematic Review/Meta-Analysis; Level III.