bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eksistensi Lahan Pasang Surut Untuk Pertanian Di Desa Mulya Sari Kabupaten Banyuasin
Authors: Helfa Septinar  , Emilia Ita , Panca Putri Yunita , Suryani Eva 
Published: December 2023

Tidal land is land that is in a zone where it is still influenced by sea tides. This land is marginal and can still be developed while maintaining water availability and pyrite oxidation. In Sumatra, Kalimantan and Irian Jaya, tidal land has been opened through the transmigration program. This land was opened as agricultural land to meet the food needs of the community. One of the efforts in managing tidal land is water management. This research aims to determine the existence of tidal land as agricultural land in Mulya Sari village. The method used is field observation, data collection through direct interviews and related literature, and descriptive analysis. The results of the research show that for the existence of tidal land, the community in Mulya Sari village optimizes the channels built by orders and also those created by the community itself. The water conditioning in each plot of land and tertiary canals is maintained by the optimal operation of the automatic water gates. In addition, the water level must be above the ground water level to prevent oxidation of the pyrite layer. Under these conditions, the tidal land in Mulya Sari village continues to exist as agricultural land.

Tidal land is land that is in a zone where it is still influenced by sea tides. This land is marginal and can still be developed while maintaining water availability and pyrite oxidation. In Sumatra, Kalimantan and Irian Jaya, tidal land has been opened through the transmigration program. This land was opened as agricultural land to meet the food needs of the community. One of the efforts in managing tidal land is water management. This research aims to determine the existence of tidal land as agricultural land in Mulya Sari village. The method used is field observation, data collection through direct interviews and related literature, and descriptive analysis. The results of the research show that for the existence of tidal land, the community in Mulya Sari village optimizes the channels built by orders and also those created by the community itself. The water conditioning in each plot of land and tertiary canals is maintained by the optimal operation of the automatic water gates. In addition, the water level must be above the ground water level to prevent oxidation of the pyrite layer. Under these conditions, the tidal land in Mulya Sari village continues to exist as agricultural land.
Relations between Russia and the DPRK in 2023
Authors: Dyachkov Ilya 
Published: December 2023

2023 witnessed a marked surge in contacts between Russia and the DPRK. Active mutual visits were the main event and the main surprise. In summer Russian defense minister Sergey Shoigu visited Pyongyang, in September North Korean leader Kim Jong-un came to Vladivostok to meet President Vladimir Putin, and in October Russian foreign minister Sergey Lavrov went to the DPRK.
After the COVID-induced break, the two countries’ representatives met face to face to seek ways to develop bilateral relations in a new political reality. Moscow and Pyongyang are concerned about the US — South Korea — Japan trilateral alliance emerging in North East Asia. Besides, practical cooperation should reach a level worthy of neighbors who have converging foreign policy views. Also, the two parties are discussing how to organize their political cooperation in the future.
Now, in a changed world, Russia promises to block all new sanctions against the DPRK in the UN Security Council, but it does not mean Moscow will neglect its duties as a permanent member or ignore sanctions that are already in effect. The quest for available profitable cooperation formats may prove arduous, and possible options might include projects in the areas of logistics, tourism, etc. Still, it is highly unlikely that Russia receives or seeks arms supplies from the DPRK, like the West claims.

As the global confrontation intensifies, North Korea keeps close to traditionally like-minded actors, but Pyongyang may yet diversify their diplomatic options should the opportunity present itself. In the meantime, Russia should use this chance to flesh out our relations with the close neighbor.
Penyegaran Kemahiran Berbahasa Indonesia Bidang Tata Kalimat dan Paragraf
Authors: Yulistio Didi 
Published: December 2023

Tujuan Pengabdian pada Masyarakat ini untuk memberikan penyegaran pengalaman Kemahiran Berbahasa Indonesia berkenaan dengan pengetahuan dan keterampilan bidang Tata Kalimat dan Paragraf Bahasa Indonesia bagi guru SMP Negeri/Swasta di Kabupaten Seluma. Tempat pelaksanaan kegiatan di hotel Arnanda, Pasar Tais Seluma dan waktu pelaksanaan hari Selasa, 8 Oktober 2019, Pukul 08.00 s.d 16.15 WIB. Sasaran kegiatan ini tercapainya perubahan sikap dan pengetahuan serta keterampilan dalam menulis kalimat dan paragraf bahasa Indonesia bagi guru bahasa Indonesia SMP Negeri/Swasta di Kabupaten Seluma, dengan jumlah peserta sebanyak 50 orang dari 32 sekolah. Metode kegiatan menggunakan metode ceramah, tanya jawab, diskusi terpimpin, intensif-partisipasif. Kegiatan dilakukan melalui presentasi materi tata kalimat dan paragraf dari narasumber dilanjutkan dengan kegiatan menulis teks sesuai persyaratan kalimat dan paragraf bahasa Indonesia yang baik. Target Capaian dalam kegiatan pengabdian pada masyarakat ini adalah tersusunnya laporan hasil kegiatan pengabdian pada masyarakat dan terjadinya perubahan pola pikir (mindset) sikap dan pengetahuan serta keterampilan dalam menggunakan kalimat dan paragraf bahasa Indonesia yang baik dalam meningkatkan kompetensi akademik guru bahasa Indonesia SMP Negeri/Swasta di Kabupaten Seluma. Hasil kegiatan pengabdian kepada masyarakat dapat dikemukakan bahwa terjadi perubahan sikap, pengetahuan, dan keterampilan pada guru bahasa Indonesia SMP Negeri/Swasta di Kabupaten Seluma dalam menggunakan kalimat dan paragraf bahasa Indonesia. Hal ini dapat dilihat dari hasil kegiatan (1) penyegaran yang mengubah sikap dan pola berpikir (mindset), guru bahasa Indonesia SMP Negeri/Swasta peserta pelatihan dalam menulis kalimat dan paragraf yang baik, benar, dan santun, (2) peserta yang bersemangat, termotivasi, dan antusias dalam mewujudkan produk tulisan kalimat dan paragraf secara baik, (3) perubahan pengetahuan dan keterampilan peserta terlihat dari cara bertanya tentang materi menulis persyaratan dan jenis kalimat dan paragraf yang baik serta mewujudkan produk tulisan yang baik, dan (3) harapan tindak lanjut kegiatan ini berupa pelatihan penulisan buku teks bahasa Indonesia untuk Siswa SMP.
Improving Interpersonal Communication Quality of Students Through Social Guidance: Evaluation of Effectiveness and Implications
Authors: Rizal Syamsul 
Published: December 2023

Social guidance is guidance given to individuals to get to know their environment so that they can socialize well and become responsible individuals which is carried out at SMP N 2 Rejang Lebong. The social problems that are often faced by students within the scope of school are related to relationships between individuals or relationships between individuals and the social environment such as difficulty in making friends, alienation from group work, and others. Research to know the interpersonal communication of students at school. This type of research is quantitative. The population in this study was students of SMP Negeri 01 and the sample population of class VII A amounted to 30 people and the sample used sampling techniques. Data collection is observation, interviews, and questionnaires. The data analysis technique with product moment correlation statistics. The results of the study The relationship between the effectiveness of student social guidance in interpersonal communication at SMP N 2 Rejang Lebong in grade VII is mostly 29.06% which is included in the influential category, which means that there is a significant influence between peers. The way of interpersonal communication between grade VIII students at SMP N 2 Rejang Lebong is mostly 37.20% who fall into the high category. High here means that most teenagers or students can already communicate with their peers.
Evaluation of New Derivatives of 2,4-dioxobutanoic Acid Salts in Behavioral Studies of Laboratory Animals
Authors: Krasnova A. I. , Polezhaeva V. D. , Pulina N. A. 
Published: December 2023

Introduction. Correction of pathological anxiety is currently an important task of modern pharmacology, since anxiety disorders are among the most common mental illnesses. Taking into account the trend of a constant increase in the incidence of anxiety and depressive disorders (ADD) in the world, the urgency of searching for various tools for studying this group of diseases and creating safe, highly effective drugs for the pharmacotherapy of ADD is growing.Aim. The study of new derivatives of salts of 2,4-dioxobutanoic acids containing fragments of benzimidazole and pyrimidine cycles on behavioral reactions of animals.Materials and methods. The salts of 4-methoxyphenyl-4-oxobut-2-enoic acid with heterocyclic amines synthesized by us were used as objects of research. Behavioral reactions of animals to the introduction of the studied compounds were evaluated using a number of tests: "open field", light/dark box", "extrapolation escape task", "forced swim".Results and discussion. The results of the experiments made it possible to identify a potentially active compound 1b, which showed an improvement in a number of indicators of motor activity of animals and an anti-anxiety effect. In addition, with the introduction of substance 1b, there is a manifestation of antidepressant activity in an acute stress situation.Conclusion. The effect of compounds 1a, 1b obtained for the first time on the behavioral reactions of animals was studied. The "structure-activity" analysis was carried out with the establishment of the priority of further targeted synthesis of salts of 2,4-dioxobutane acid derivatives containing a fragment of 2-aminopyrimidine. A compound with a neuropsychotropic activity profile has been identified, which is recommended for further in-depth study.
Prospects for the Search for New Antidiabetic Agents Among Vanadium-containing Complex Compounds (Review)
Authors: Krasnova A. I. , Pulina N. A. , Yushkova T. A. 
Published: December 2023

Introduction. The epidemic increase in the incidence of diabetes mellitus (DM) makes it urgent to search for new antidiabetic agents. In clinical practice, there is an urgent question about improving and/or replacing insulin therapy for the disease. Vanadium compounds are of particular interest in connection with the identification of their multifactorial effects on the body, including insulin-like and hypoglycemic properties, which opens up prospects for the creation of a new generation of therapeutic agents for the treatment of types 1 and 2 diabetes. The focus of this review is on the structure and antidiabetic properties of vanadium complexes.Text. This review is devoted to the analysis of scientific literature on studies of vanadium-containing compounds as potential antidiabetic agents. The mechanisms of antidiabetic activity of vanadium-containing complex compounds are discussed. The prospects for searching for oxovanadium(IV) complexes with O4-coordination have been assessed.Conclusion. As a result of the analysis of the literature data, it was found that vanadium-containing complex compounds have a significant potential for use as antidiabetic agents. The relevance of the search for highly effective oxo-vanadium metal complexes based on ligands close to endogenous substrates, for example, based on derivatives of aroylpyruvic acid, is shown.
Biological Activity study of the <i>Melampyrum sylvaticum</i> Extract
Authors: Galishevskaya E. E. , Polyakova E. N. , Bombela T. V. , Agafontseva A. V. , Anisimova A. G. , Krotkova O. A. , Yagontseva T. A. , Luzhanin V. G. , Kurbatov E. R. 
Published: December 2023

Introduction. Among wild plants that have an effect on the nervous system, species of the genus Melampyrum L. are distinguished, in particular, Melampyrum sylvaticum L. Extracts from the aerial part of the plant have long been used in folk medicine as sedatives and anticonvulsants. Currently, a number of studies are being carried out to confirm the possibility of using wildflower and drugs based on it in scientific medicine, as well as to obtain a drug with low toxicity, complex sedative and anticonvulsant activity, which will expand the arsenal of drugs used to treat diseases of the nervous system.Aim. To investigate the in vivo acute toxicity, anticonvulsant and sedative activity of a dry alcohol extract from the aerial part of Melampyrum sylvaticum.Materials and methods. The extract was obtained by extracting substances from the aerial part of Melampyrum sylvaticum with 50 % ethanol, by the method of repercolation with an equal loading of raw materials, followed by evaporation to a dry residue. The study of pharmacological properties was carried out on nonlinear white mice of both sexes weighing 17–25 g. Acute toxicity of the extract was determined by oral administration in doses up to 5000 mg/kg. Anticonvulsant activity was evaluated in the corazole convulsion test, sedative activity was evaluated in the open field test.Results and discussion. When determining the acute toxicity of a dry alcoholic extract from the aerial part of Melampyrum sylvaticum, there was no lethality in the experimental group of animals. LD50 could not be determined. In the corazol convulsion test, it was shown that oral administration of the extract at a dose of 100 mg/kg does not affect the latent period of convulsions, but significantly increases the life expectancy of animals. At a dose of 200 mg/kg, the latent period of seizures and life expectancy significantly increased, and the survival rate of animals was 20 %. When studying sedative activity of the extract from Melampyrum sylvaticum in the open field test, a decrease in vertical activity, a decrease in the number of vertical stands, a decrease in horizontal activity along the periphery and the number of animals entering the center of the area were noted, which indicates a suppression of orienting-exploratory behavior. In the experiment, there was a decrease in the intensity of grooming as an indicator of anxiety for this group of animals. A course of administration of the extract for thirty days led to a decrease in the vertical activity of mice and inhibition of orienting-exploratory behavior.Conclusion. It was found that a dry alcoholic extract from the aerial part of Melampyrum sylvaticum exhibits biological activity in animal experiments, compensating for the effect of corazol, and has a pronounced anticonvulsant and sedative effect. The LD50 of the extract when administered orally was more than 5000 mg/kg.
Evaluation of the Antioxidant Properties and Cytotoxic Activity of 1,3-dioxolane Derivatives Imidazole
Authors: Zykova S. S. , Shustov M. V. , Talismanov V. S. 
Published: December 2023

Introduction. Modern chemotherapy widely considers the role of antioxidant and pro-oxidant methods in the treatment of oncologic pathologies. The use of agents that cause an increase of ROS is a relevant way to destroy tumors. At the same time, there is evidence of the ability of some antioxidants to lead to the cancer cells apoptosis through the generation of free radical forms of oxygen due to disruption of cellular homeostasis. The combination of the «Ecolum» biosensor using technique, antiradical activity data, and information about the cytotoxicity of compounds used in the study allows us to consistently conduct low-cost screening of as antioxidant, as antiradical activities and potentially reduce the required number of expensive cytotoxicity determinations using tumor cells.Aim. The main target of our work is the evaluation of antioxidant and cytotoxic activities of 1,3-dioxolane derivatives of imidazole using antioxidant, antiradical and cytotoxicity tests in vitro.Materials and methods. To carry out this study, 1,3-dioxolane derivatives of imidazole were obtained. The antiradical tests was performed using the DPPH (2,2-diphenyl-1-picrylhydrazyl) method. Antioxidant properties were assessed within the Ecolum biosensor in the state of oxidative stress. Cytotoxic activity was assessed in GIST-T1 cell culture using the MTT test (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide).Results and discussion. Data from studies of the antioxidant activity of substances using the «Ecolum» biosensor showed varying degrees of damage to the biosensor in the absence of antioxidant action. The antiradical potential, initially used to reveal a possible mechanism of antioxidant action, actually demonstrated a possible mechanism of toxic action of substance 2c due to its antiradical effect comparable to the standard (Trolox), but the substance has the highest cytotoxicity. However, the properties of substance 2a shows that the direct correlation discussed earlier is not found in all cases.Conclusion. The asessment of the antioxidant properties and cytotoxic activity of 1,3-dioxolane derivatives of imidazole demonstrated the relevance of further searching for connections between the results of substances binding with the Ecolum biosensor under conditions of oxidative stress, their antiradical potential and cytotoxic properties. This combination of tests will potentially reduce the cost of screening through the use of an available biosensor, establish a possible mechanism of action aimed at redox balance, and confirm previously obtained data through the use of tumor cell culture.
Synthesis and Quality Control of Calcium Chelidonate Substance with Osteogenic Activity
Authors: Avdeeva E. Yu. , Igidov N. M. , Gein V. L. , Krivoshchekov S. V. , Khlusov I. A. , Belousov M. V. , Dozmorova N. V. , Luzhanin V. G. 
Published: December 2023

Introduction. Osteogenic agents are used for pathologies associated with impaired bone formation, complications of bone fractures, the use of implants and endoprostheses, and tumor lesions of bone tissue. High osteogenic activity in vivo on the model of experimental osteomyelitis, in vitro and in situ on mesenchymal stem cells was revealed for calcium chelidonate, which is a promising substance for the production of osteogenic drugs.Aim. Development of a method for obtaining the calcium chelidonate substance by chemical synthesis and methods of its standardization.Materials and methods. The synthesis of chelidonic acid was carried out on the basis of diethyloxalate; calcium chelidonate – using synthesized chelidonic acid and anhydrous calcium chloride. The structure of the substances was confirmed by optical spectral methods, mass spectrometry, elemental and X-ray structural analysis. The quantitative content was assessed using a liquid chromatograph. Statistical processing of the results of quantitative measurements was carried out in the STATISTICA 8,0 program.Results and discussion. As a result of the synthesis, chelidonic acid (4-oxo-4H-piran-2,6-dicarboxylic acid) was obtained, which is colorless or cream-tinged crystals. The structure of the resulting compound is confirmed by spectral characteristics and elemental analysis data. A method for obtaining the calcium chelidonate substance has been worked out, while the yield of the target product was 100 ± 5 %. By X-ray structural analysis, it was found that the synthesized compound is calcium chelidonate trihydrate [Ca(ChA)(H2O)3]n with M.M. (C7H8O9Ca) 276,15. Methods for establishing authenticity, purity and quantification of the substance have been developed. The amount of impurities in the resulting substance did not exceed 0.1 %, and the content of the main component ranged from 99,2 ± 0,20 to 100,4 ± 0,35 %.Conclusion. Due to the limited resource reserves and the complexity of the process of extracting chelidonic acid from plant raw materials, a method for the chemical synthesis of calcium chelidonate substance with osteogenic activity is proposed. The obtained results provide prospects for further research in the direction of the development and introduction of synthetic calcium chelidonate as a new osteogenic drug, provided that the specific biological activity is comparable to the natural analogue.
ANALISIS KEBIJAKAN PENGARUSUTAMAAN GENDER (PUG) DI MTS AL-MA'HAD AN NUR
Authors: Mawarni Fadila Uyun , Afita Anisatul , Iriani Rigitha Ayu , Saputri Fania Albani , Abdilah Maryam Nisrina 
Published: December 2023

Isu gender sudah menjadi perhatian global dan dinamikanya terus dikaji dari waktu ke waktu. Pengarusutamaan gender atau PUG merupakan sebuah strategi yang dilakukan pemerintah secara sistematis dan rasional dalam mencapai sebuah keadilan dan kesetaraan terhadap peran atau gender laki-laki dan perempuan dalam semua aspek kehidupan manusia. Penelitian ini menerapkan metode penelitian kualitatif. Adapun lokasi penelitian yang diambil adalah MTs Al Ma'had An Nur, Ngrukem, Bantul, DIY. Penelitian ini menggunakan data primer yang dilaksanakan dengan cara observasi, wawancara dan dokumentasi. Berdasarkan hasil penelitian yang telah dilakukan nampak terlihat bahwasanya di MTs Al-Ma'had An Nur dalam pelaksanaan kebijakan pengarusutamaan gender di sekolah aktor yang terlibat dan memiliki peran penting, sepertiÂ guru, staf atau karyawan, dan peserta didik yang mana justru lebih didominasi oleh kaum perempuan. Sedangkan untuk peran dan posisi kepala sekolah masih didominasi oleh laki-laki. MTs Al-Ma'had An Nur memiliki 27 kelas dengan jumlah peserta didiknya sebanyak 896 yangÂ berasal dari berbagai daerah di Indonesia, seperti Aceh, Sumatera, Kalimantan, Sulawesi, Papua, dan Jawa. Untuk jumlah guru terdapat 54, dengan mayoritas guru perempuan.
Peran Yayasan Surya Pringga Dermayu dalam Pelestarian Manuskrip Koleksi Masyarakat Indramayu
Authors: Rosyiqoh Humairotur , Hayati Nurul , Lolytasari Lolytasari 
Published: December 2023

Manuscripts, often overlooked by the government and society, hold crucial information, with the Yayasan Surya Pringga Dermayu standing out as a dedicated activist organization in Indramayu, striving to preserve this cultural heritage. This study investigates the organization's preservation efforts and how they navigate challenges. Two main strategies emerge: physical preservation involves conservation activities, cleaning, and storage, while content preservation employs transliteration, recopying, and digitization in collaboration with governmental and international entities. Obstacles include the lack of a set maintenance schedule, limited human resources, and insufficient funding. Mitigation efforts involve periodic maintenance, urging youth involvement, and collaboration with local governments. The Surya Pringga Dermayu foundation serves as a noteworthy example, emphasizing the need for broader societal and governmental recognition of manuscript preservation's importance.
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Manuskrip menyimpan informasi penting yang sering kali dianggap kurang mendapat perhatian. Sanggar Aksara Jawa Surya Pringga Dermayu menonjol sebagai organisasi pelestari naskah di Indramayu yang berdedikasi melestarikan warisan budaya ini. Penelitian ini mengeksplorasi upaya pelestarian organisasi dan bagaimana mereka mengatasi tantangan. Terdapat dua strategi utama: pelestarian fisik melibatkan kegiatan konservasi, pembersihan, dan penyimpanan, sementara pelestarian konten melibatkan transliterasi, penyalinan, dan digitalisasi dengan kerjasama lembaga pemerintah dan internasional. Kendala melibatkan jadwal pemeliharaan yang tidak pasti, sumber daya manusia yang terbatas, dan pendanaan yang kurang memadai. Upaya mitigasi melibatkan pemeliharaan berkala, dorongan partisipasi pemuda, dan kerja sama dengan pemerintah setempat. Sanggar Aksara Jawa Surya Pringga Dermayu menjadi contoh nyata, menekankan perlunya pengakuan lebih luas dari masyarakat dan pemerintah akan pentingnya pelestarian manuskrip.