bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hypoxia Protocols in a Normobaric Environment for Aviators: a Scoping Review
Authors: Paula Tainah de , Haberland Debora Fernanda , Calvo Adriano Percival Calderaro , Guilherme Fábio José de Almeida , Coutinho André Brand Bezerra , Ferreira Domenica Baroni Coelho de Oliveira , Guimarães Thiago Teixeira 
Published: January 2025

Objective: Identify the protocols used in normobaric hypoxia and the main symptoms in that context.

Theoretical Framework: Hypoxia, particularly hypoxic hypoxia, is a critical challenge in aviation, caused by reduced atmospheric pressure at high altitudes. Controlled hypoxia training allows aviators to recognize symptoms, assess the time of useful consciousness, and practice emergency responses. This study synthesizes key parameters in normobaric hypoxia training, addressing gaps in oxygen concentrations, exposure times, and symptom monitoring.

Method: Systematic electronic searches were conducted in MEDLINE and Embase databases. Inclusion criteria required original studies involving aircraft crews, descriptions of gas mixtures used for altitude simulation, and details of simulated altitudes during training.

Results and Discussion: From 295 identified articles, eight met the inclusion criteria. Sample sizes ranged from 8 to 89 participants, predominantly male. Protocols varied widely, with O₂ concentrations of 6%, 7%, and 8% frequently used to simulate altitudes of 25,919 feet (7,900 m) to 20,341 feet (6,200 m). Considerable heterogeneity was found in protocols for the same simulated altitude, likely due to differences in equipment calibration. Continuous exposure periods of three to five minutes were common, and diverse hypoxia symptoms were reported, emphasizing the importance of symptom recognition for operational safety.

Research Implications: This study offers practical insights for standardizing hypoxia training protocols, enhancing safety procedures, and developing guidelines for normobaric environments.

Originality/Value: By synthesizing hypoxia training parameters, this research highlights the need for protocol standardization to ensure aviator safety and operational efficiency.
Strain Energy and Biomechanical Constituent Models in Blood Vessel Tissues
Authors: Lélis José María Rodríguez , Pérez Oscar Domínguez 
Published: January 2025

Objective: To show the analysis of mechanical constitutive models in blood vessel tissues with a continuous media approach based on strain energy, which serve as a reference for new mathematical modeling proposals in them.

Theoretical Framework: The mechanics of blood vessels, describes the structural and functional behavior of blood vessels and can characterize various cardiovascular diseases. Harmful changes that alter the mechanical response of the walls of blood vessels produce severe alterations in the health of the circulatory system. Predicting the mechanical behavior of blood vessels based on physiological status using biomechanical models is paramount for diagnosis. Therefore, in the present work, an analysis of the constitutive models is carried out with a continuous media approach based on strain energy.

Method: Bibliographic review that identifies, analyzes and synthesizes the existing scientific proposals on blood vessel tissue modeling based on the deformation energy theory.

Results and Discussion: A bibliographic study of the biomechanical constitutive models of blood vessel walls, generated over time, is presented. The behavior of the vascular wall is analyzed from the deformation energy approach. The benefits, limitations and potentialities of the models are also exposed: a) Strain energy with a transversely isotropic and homogeneous matrix; b) Strain energy with axis-symmetric fiber constants; c) Strain energy with collagen fibers subject to dispersion; d) Strain energy of four families of fibers without dispersion; and e) Strain energy of two families of fibers with anisotropic elastin and fiber recruitment.

Implications of the research: The conclusions and analyzes presented serve as a basis for future research and mathematical modeling of the phenomenon of degradation and deformation of blood vessels, which will facilitate the understanding of the phenomenon and the subsequent strengthening of alternative treatment strategies that combat the clinical conditions derived from the transformations of mechanical properties in the same blood vessels.

Originality/Value: This study contributes by giving order to the multiple bibliographic information related to the subject. The relevance of this research is evidenced in the conclusions issued when analyzing models based on the theory of continuous media as a function of strain energy.
Curricular Integration of Mathematics and Dance to Improve Geometric Reasoning in Secondary School Students
Authors: Suárez Yanira Mayerly Salinas , González Mariacarla Martí 
Published: January 2025

Objective: The objective of this study is to investigate the effectiveness of integrating dance into mathematics education, with the purpose of improving geometric reasoning among secondary school students in Colombia and increasing their interest in STEAM disciplines.

Theoretical Framework: This section presents the main concepts and theories supporting the research. Notable among these are theories of geometric reasoning, such as the Van Hiele model, as well as theories of interdisciplinary education in STEM and STEAM. These theories provide a solid foundation for understanding how integrating artistic disciplines, such as dance, can influence mathematics learning and activate students' creativity.

Method: The methodology adopted for this research includes a pre-post test design using the Van Hiele Test to measure geometric reasoning. The sample consisted of three groups of secondary school students in Colombia. A curricular integration proposal linking dance with mathematics was implemented, and results were evaluated before and after the intervention to determine its impact on geometric reasoning.

Results and Discussion: The results revealed significant improvements in students' geometric reasoning following the intervention, with notable gains in visualization and recognition levels according to the Van Hiele Test. In the discussion section, these results are contextualized within the theoretical framework, highlighting how integrating dance into mathematics teaching can overcome fragmented knowledge and increase students' interest in STEAM disciplines. Possible study limitations, such as sample size and intervention duration, are also considered.

Research Implications: The practical and theoretical implications of this research are discussed, providing information on how the results can be applied to educational practices to improve performance in STEAM disciplines. These implications could include reformulating school curricula to incorporate interdisciplinary approaches that integrate arts and sciences, particularly in the context of secondary education in Colombia.

Originality/Value: This study contributes to the literature by demonstrating the effectiveness of an innovative proposal that integrates dance into mathematics education to improve geometric reasoning. The relevance and value of this research are evidenced by its potential to transform the way STEAM disciplines are taught, offering a more creative and interdisciplinary approach that can motivate more students to pursue careers in science, technology, engineering, art, and mathematics.
Environmental Law and Green Marketing: Perspectives for Sustainable Consumption
Authors: Moraes Alex Souza , Mezzomo Agnaldo Luiz , Pacheco Clecia Simone Gonçalves Rosa , Santos Reinaldo Pacheco dos , Moreira Márcia Bento , Oliveira Maira Danuse Santos de , Oliveira Deivison Ferreira , Chagas Samaira Cristina Souza , Campos Daniel Ferreira , Bonomo Brunno , Diniz Mateus Henrique dos Santos , Araújo Nícolas Matheus da Fonseca Tinoco de Souza , Brito Clara Rodrigues de , Cruz Tereza Cristina de Souza Freitas da 
Published: January 2025

Objective: This study aimed to analyze the relationship between environmental law and green marketing, exploring its perspectives for sustainable consumption.

Methodology: The research adopted a qualitative descriptive approach, with a sample made up of 15 professionals in the areas of environmental law and marketing.

Results: Data collection was carried out through semi-structured interviews, and data analysis followed the content analysis technique. The results indicated that, although companies are increasingly paying attention to sustainability and green marketing, they still face significant challenges, such as internal resistance, the cost of adaptation and the practice of greenwashing. Furthermore, environmental regulation has proven essential to guarantee transparency in business actions.

Conclusion: The conclusion points out that, to promote sustainable consumption, a joint effort between governments, companies and consumers is necessary, with an emphasis on environmental education and transparency in business practices, in addition to strengthening environmental legislation.
Satisfaction Assessment of Training in Artificial Intelligence With a Focus on Sustainable Projects for the Amazon
Authors: Maranhão Geraldo Neves de Albuquerque , Oliveira Werbeston Douglas de , Brito Alaan Ubaiara , Vasconcelos Osvaldo Campelo de Mello , Siqueira Marcelo Ricardo Souza 
Published: January 2025

Objective: To list challenges and assess student satisfaction with training in artificial intelligence focused on developing sustainable projects for the Amazon.

Theoretical Framework: AI refers to systems that model human intelligence to perform tasks, improving based on collected information. The digital transformation market has seen significant growth, with global investments expected to reach $665 billion by 2023.

Method: The applied methodology consisted of a quantitative and qualitative approach. A specific form was used for the demographic study and student satisfaction. Only students who completed the training were included in the research.

Results and Discussion: The sample used had a margin of error of 9.40% with a confidence level of 90%. The research conducted with the participants revealed a high satisfaction rate, with 98.1% of students declaring themselves satisfied or very satisfied with the offered training.

Research Implications: The research revealed several important aspects of the training provided, the difficulties faced by the students, and their satisfaction in carrying out the specific activities of the course considering its various modules.

Originality/Value: This training consisted of a pilot project by the Federal University of Amapá in partnership with the International Software Technology Center (CITS) that brings an innovative approach to developing sustainable projects for the Amazon using technical knowledge in Artificial Intelligence and considering high school and elementary school students.
Assessment of Water Quality in a Public Supply Source: Combined With the General Index of Human Contamination
Authors: Constantino Wellington Leandro , Monego Maurici Luzia Del , Lima Bárbara Alves de , Medeiros Samanta Teixeira , Peixoto Luiz Otávio , Azevedo Júlio César Rodrigues de 
Published: January 2025

Objective: The aim of this study was to evaluate the water quality of the Miringuava River watershed through monitoring of chemical water quality parameters, assess the presence of Emerging Contaminants (EC) such as hormones and caffeine, and determine the General Index of Human Contamination (GIHC).

Theoretical Framework: Watersheds located near urbanized areas play a crucial role in water resource management, especially when used for public supply. Due to land use and occupation, the natural dynamics of rivers, and reurbanization processes, monitoring water quality within a watershed is necessary (Pereira et al., 2021). Consequently, the social impact and effects on aquatic environments must be considered (Sekamane et al., 2023).

Method: Two collections were conducted (C1 with 7 points and C2 with 16 points) upstream of the water intake station of SANEPAR to obtain water samples from the Miringuava River watershed. The methodology was defined in four stages: Definition of sampling points, sending water samples to the LEAQUA Laboratory – UTFPR, analysis of the data processed by the laboratory, and construction of the GIHC graphs.

Results and Discussion: The results obtained revealed the presence of Emerging Contaminants in some water bodies in the region. Considering the hormone Estradiol (E2), which is an emerging contaminant, Ide et al., (2017) found a maximum value of 1420 ng L-1 in the Iguaçu River basin. In comparison, the values found in the Miringuava River basin were 23.14 ng L-1, indicating that the level of estradiol is considered low.

Research Implications: The practical and theoretical implications of this research indicate that there are already signs of minor contamination in the water bodies of the Miringuava River basin. Such implications demonstrate the need for monitoring in the region.

Originality/Value: This study contributes to the understanding and confirmation of the presence of emerging contaminants in the Miringuava River basin, which will be used for public supply. By evaluating chemical parameters and the General Index of Human Contamination, it provides important information for water quality management in the region.
Law Enforcement on Criminal Acts of Fuel Oil Distribution Illegally Subsided
Authors: Surya Achmad , Suhartini Suhartini 
Published: January 2025

Misuse of distribution of fuel oil (BBM) often occurs illegally, to gain individual or business entity benefits by harming the interests of the general public and the state. This act is against the law and can be subject to criminal penalties as regulated in Law Number 22 of 2001 concerning Oil and Gas. This type of research is empirical law using primary data obtained directly from the field through interviews with related parties, while secondary data obtained through library data in the form of primary legal materials, namely binding regulations, secondary and tertiary materials. Research results show, law enforcement against the illegal distribution of subsidized fuel oil (BBM) has never been carried out by the Central Aceh Resort Police, due to the absence of reports from the public. The efforts of police investigators in overcoming the crime of distributing subsidized fuel oil (BBM) in Central Aceh Regency. First, Supervise the distribution of subsidized fuel in cooperation with local governments, as well as coordinate with owners of Public Fuel Filling Stations (SPBU). Second, urge the public to report to the police if it is found that the distribution of subsidized fuel is illegal
Land Dispute Resolution: Village Deliberation and Consensus to Establish Public Order
Authors: Gunawan Yoga , Dialog Bias Lintang , Fitriana Diana 
Published: January 2025

Land disputes are common in society, and the village head, as witnessed by the family, resolved the matter in congruent with the parties' will and good intention. Purpose to investigate the arrangement of land dispute resolution in Indonesia; and to investigate its application through consensus deliberation in villages to realize public order. Methodology an socio-legal approach, involving primary data gathered from the interview. Furthermore, the study was also conducted in Kuningan Regency. Findings in Indonesia, land disputes resolution have been completely regulated, ranging from laws to derivative regulations and is carried out through community discourse and consensus. However, deliberation method is more common than going to the court. The deliberations include bringing the parties together; if peace arrangements can be made, they will be made. It can, however, only function optimally if both sides (the family and the community) agree to deliberate. The method is thought to be more efficient in terms of time, cost, and mechanism. Conclusion in the village, there are two procedures for resolving land conflicts through consensus deliberation: mediation and family negotiation. Recommendation at the village level, it is critical to provide a legal framework for deliberation so that the outcomes are more equitable and mutually beneficial to all parties.
The Regulation of Legal Responsibility: Illegal Logging Perpetrators in Indonesia and Nigeria
Authors: Akhmaddhian Suwari , Okolie Ugo Chuks , Hidayat Sarip , Andriyani Yani , Tiaranita Intan 
Published: January 2025

The study aims to analyze the offenders of illegal logging in Indonesia and Nigeria from its legal liability regulations. The study employed an socio-legal approach involving literary analyses on legal materials used─the statutory regulations, scientific journals and other pertinent documents. The results shows that legal responsibility for illegal logging perpetrators in Indonesia are under the Law on Forestry, the Law on Prevention and Eradication of Forest Destruction, and the Law on Cipta Kerja. In Nigeria, it is governed by several states, such as the Edo State Forestry (Amendment) Law 2002; Cross River State Forestry Commission Law 2010; and Taraba State Forestry Law 2010. Finally, the legal responsibility for illegal logging has been established in both countries. Accordingly, the indonesian government is suggested to disseminate the latest laws and regulations, so that the public and corporations are aware of them. Meanwhile, Nigerian government is expected to immediately issue nationwide legislation on illegal logging, so that law enforcement is not relied solely on the requirements of each state
Social Impact of Converting Rice Field Agricultural Land into Housing
Authors: Yuniati Ati , Hamidah Upik , Nurmayani Nurmayani , Deviani Eka 
Published: January 2025

Land conversion refers to the shift in the use or function of land, which has become increasingly common due to population growth and the rising demand for housing, food, and infrastructure. In Pesawaran Regency, particularly in Mada Jaya Village, the conversion of rice fields into housing presents both procedural challenges and significant social impacts. This study examines the process of land conversion and its social consequences, focusing on two key questions: how the conversion process is carried out and what social impacts arise from it. This study applies Talcott Parsons' functional structural theory using the AGIL framework, supported by legal analysis and field studies, to offer practical insights into sustainable land management. The findings reveal that while land conversion should follow legal procedures, such as obtaining a Location Permit (IPPT) and land use transfer permits—discrepancies occur in practice. Some agricultural land has been pre-filled with soil, classifying it as productive land and making it ineligible for conversion permits. The social impacts include reduced food availability, unemployment, and economic instability, despite some landowners benefiting from land sales. To address these challenges, stricter enforcement of regulations, community participation, and support programs for displaced workers are needed. Economic diversification, such as small business development and agro-tourism, is also recommended.
Jumonji domain-containing protein 6 promotes gastric cancer progression: Modulating immune evasion through autophagy and oxidative stress pathways
Authors: Zhang Xinyue , Na Di 
Published: January 2025

Objective:
Immune response is crucial in the development of gastric cancer (GC), and Jumonji domain-containing protein 6 (JMJD6) plays an important role in mediating GC cell behavior. This study aims to elucidate the mechanisms through which JMJD6 affects autophagy and immune evasion in GC cells.

Material and Methods:
Immunocytochemistry was employed to assess JMJD6 and programmed death-ligand 1 (PD-L1) levels in gastric cancer cell line (MKN-45) and gastric epithelial cell line cells. MKN-45 cells with JMJD6 knockdown and overexpression were generated. The effect of JMJD6 on MKN-45 cells was evaluated using cell counting kit-8 assay, cellular fluorescence staining, and Transwell assays. Western blot analysis and immunofluorescence techniques were employed to investigate the regulation of autophagy by JMJD6. Reactive oxygen species (ROS) levels were evaluated by applying ROS fluorescence staining. Meanwhile, the protein and gene expression levels of molecules related to antioxidant stress responses were assessed through immunofluorescence assays and quantitative real-time polymerase chain reactions, respectively.

Results:
The expression levels of JMJD6 and PD-L1 were elevated in GC cells (P < 0.001). JMJD6 overexpression enhanced MKN-45 cell migration, invasion, and colony formation in vitro (P < 0.001). In MKN-45 cells, the epithelial-mesenchymal transition was promoted by JMJD6 upregulation but was notably inhibited by JMJD6 knockdown (P < 0.001). JMJD6 overexpression increased the expression levels of Sequestosome 1, Microtubule-associated protein 1A/1B-light chain 3 (LC3)II/LC3I, and PD-L1 in MKN-45 cells, and autophagy activation further elevated PD-L1 levels (P < 0.001). In addition, JMJD6 overexpression reduced ROS production and increased the expression of molecules related to antioxidant stress response, with the reverse effects observed on JMJD6 knockdown (P < 0.001).

Conclusion:
JMJD6 notably facilitates GC progression and immune evasion by modulating autophagy and oxidative stress pathways.
Pengaruh Pengendalian Akuntansi, Sistem Pelaporan, Dan Kejelasan Sasaran Anggaran Terhadap Akuntabilitas Kinerja Instansi Pemerintah Kabupaten Pekalongan
Authors: Dini Indriyani  , Shulthoni Muhammad 
Published: January 2025

The change in regional budget standards is to create regional budgets accurately and economically, efficiently, and effectively that represent the interests and aspirations of local communities in relation to regional financial management. Accountability must be fulfilled by the government by looking at the budget, accounting control, and reporting system. The purpose of this study is to determine the effect of accounting control, reporting system, and clarity of budget targets on the accountability of the performance of government agencies of Pekalongan Regency. This research belongs to the type of quantitative research. The data collection method in this study was a questionnaire method using a sample of 51 respondents. Sampling technique by purposive sampling method. This study used a multiple linear regression test data analysis method with the help of SPSS 26. The results showed that accounting control affects the accountability of the performance of government agencies in Pekalongan District. The reporting system and clarity of budget targets do not affect the accountability of the performance of government agencies in Pekalongan District.