bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preparation of antistatic and biodegradable packaging of PLA/PHBV blend‐based glassy carbon and graphene nanoplatelets composites
Authors: Oyama Isabela Monteiro Cesar , dos Anjos Erick Gabriel Ribeiro , de Melo Morgado Guilherme Ferreira , Brazil Tayra Rodrigues , Kantun‐Uicab María Cristina , Passador Fabio Roberto 
Published: November 2023

AbstractGlassy carbon (GC) and graphene nanoplatelets (GNP) were used as fillers for the preparation of antistatic and biodegradable composites based on poly (lactic acid)/poly(3‐hydroxybutyrate‐co‐3‐hydroxyvalerate) (PLA/PHBV) blend. In this work, PLA/PHBV (80/20) blends with the addition of different GC contents (0.1, 0.3, and 0.5 wt%) were prepared by melt mixing using a twin‐screw extruder, and specimens were injection molded. Furthermore, hybrid composites were prepared with the addition of 5 wt% of GNP and different GC contents (0.1, 0.3, and 0.5 wt%) using the same processing. The effect of the addition of GC and GNP on the mechanical, electrical, and electromagnetic properties and its effect on the biodegradability of the PLA/PHVB blend was evaluated. The simultaneous addition of GC (0.3 and 0.5 wt%) and GNP (5 wt%) significantly increases the elastic modulus and decreases the electrical resistivity, becoming suitable for electrostatic discharge protection packaging applications. The hybrid composite GC0.5/GNP5 reached a maximum value of total attenuation (4.5 dB), which corresponds to 60% EMI shielding. The degree of crystallinity affects biodegradability more than the type or presence of carbon material. After 110 days of anaerobic biodegradation, the hybrid composite exhibited 10% biodegradability due to the high degree of crystallinity that hinders the biodegradability process. The hybrid composites with the addition of GC and GNP are very promising for use in antistatic packaging.
The emotional appeal of shared fantasies in Nazi propaganda: A psychoanalytic view
Authors: Hartman John J. 
Published: November 2023

AbstractThis paper explores the emotional appeal of Nazi propaganda from a psychoanalytic point of view. A shared ideological narrative connecting to unconscious fantasies within a large group psychology are utilized to explain this emotional appeal in the context of an intersubjective leader‐audience relationship. A narrative of narcissistic revenge, apocalyptic battle, and utopian unity and purification are explored utilizing speeches of Hitler as examples of ideological transmission. Prophesizing the extermination of the Jews of Europe is understood as integral to the emotional appeal of Nazi propaganda.
Geoarchaeological investigations in Artanish Peninsula, Armenia: Testing a new geochemical prospecting method for archaeology
Authors: Hovhannisyan Arshavir , Bobokhyan Arsen , Kunze René , Fassbinder Jörg W. E. , Hahn Sandra E. , Arakelyan Dmitri , Grigoryan Avetis , Harutyunyan Marianna , Siradeghyan Varduhi 
Published: November 2023

AbstractWithin the framework of an Armenian–German research project, taking place between 2019 and 2021 on the Artanish Peninsula at Lake Sevan (Armenia), in addition to numerous (geo‐) archaeological investigations, methods of geochemical prospection have been carried out. The ancient burial grounds of Artanish 23 and Artanish 29 have served as model sites to successfully test the well‐known method of geochemical prospection and evaluation of metal deposits in geology (mineral sector). As a result, a new experimental archaeo‐geochemical prospecting and evaluation method has been developed, which has been adapted for the exploration of archaeological monuments. It is planned to use this experimental method (which we consider new and important in archaeogeochemical investigation, but not a conclusive and comprehensive work per se), which has already proven its work capacity, in archaeological research, in the prospective areas of Armenia and other countries. In addition to these investigations, research on the transformations in the landscape of the ancient tombs related to Lake Sevan fluctuations has also been carried out. The anthropogenic impact of humans on the environment (geochemical halos formed in the soil on the surface of the tombs) has been studied, as well as the problem of the impact of geological environment on human life activities, that is, the relocation of the burial grounds to more elevated areas due to the rise in the lake level. Based on the results of geochemical sampling and high‐resolution magnetometer surveys, excavations have been performed at the site. Here, we present the results of an experimental study exploring the potential of combined magnetometer prospection and chemical soil analyses to locate and characterize the burial ground of Artanish on Lake Sevan, Armenia. The results have demonstrated the capability of these analyses to detect the sites, outline hotspots and interpret the features identified in the magnetometer results.
The challenges of signal interpretation of burials in ground‐penetrating radar
Authors: Martindale Andrew , Wadsworth William T. D. , Simons Eric , Whiting Brian , Grier Colin 
Published: November 2023

AbstractThe identification of unmarked graves and burials is one of most common applications of ground‐penetrating radar (GPR) in archaeology. Despite a high frequency of use and a long history of experimentation, there appears to be considerable variability on what indicates a burial in GPR data—likely a consequence of heterogeneity in geological contexts, age and in burial practices. Although general statements about uncertainty in GPR interpretation may be acceptable in archaeological applications, the interpretative process becomes more complicated when GPR is used to locate unmarked graves in culturally, politically and legally contested locations such as at former Indian Residential Schools (IRSs) in Canada. In this paper, we review international applications of the technique and identify trends and traits between the authors' use of GPR to identify burials. By categorizing the studies based on the GPR reflection signatures identified, our review demonstrates that there is modest consensus across the 77 documents reviewed for what represents a burial. Interrogating these findings, we identify a range of potential contributors to signal heterogeneity and outline potential steps forward to a higher confidence or more statistically robust identification of unmarked graves using GPR.
Robust Laguerre‐based model predictive control for trajectory tracking of a mobile robot using an linear matrix inequality (LMI)‐based approach
Authors: Jamalabadi Marzieh , Firouzmand Elnaz , Sharifi Iman , Naraghi Mahyar 
Published: November 2023

AbstractThis paper studies the trajectory tracking of a constrained mobile robot under slippery conditions. The goal is to propose a controller for real‐time operations of time‐varying dynamics with insignificant execution time. Therefore, a Laguerre‐based model predictive control (LMPC) is designed, and robustness is provided with an linear matrix inequality (LMI)‐feedback controller. Moreover, a recursive least square (RLS) algorithm with a forgetting factor is utilized to identify the required parameters of the LMI‐based controller. LMPC and LMI‐based controller stability is achieved with suboptimal theory and Lyapunov function, respectively. This algorithm separates the nominal system and introduces new dynamics containing uncertainties. Furthermore, LMPC is removed from the online calculation, which dramatically reduces computation burden and time; consequently, online computation is dedicated to determining the LMI feedback. Simulations are provided to compare the proposed robust controller to its not robust counterpart. Finally, it is demonstrated that this controller diminishes the execution time considerably, making it incomparable to previous robust MPC strategies.
Robust control scheme for uncertain semi‐Markov jump systems subject to digital communication constraint and incomplete sojourn‐time information
Authors: Zhang Linchuang , Du Xinye , Sun Yonghui , Zhai Suwei , Wang Yi , Zhou Wei 
Published: November 2023

AbstractThis paper deals with the robust control problem for networked uncertain semi‐Markov jump systems over digital communication channel, where some complicated factors are considered in this framework, such as false data injection attacks, incomplete sojourn‐time information, and actuator fault. In network environment, these problems frequently occurred: (1) Data must be quantified before it is transmitted via digital communication channels, and (2) there is always the risk of cyber‐attack. Traditional controllers are not effective to solve the robust control design issue of uncertain semi‐Markov jump systems since the signal quantization and cyber‐attack will degrade control performance evidently. Then, a resilient controller is designed to guarantee the stable running of system with incomplete sojourn‐time information and the system resiliency to unsecure shared data. With the help of Lyapunov stability theory, sufficient conditions are derived in the form of linear matrix inequality, which can determine the gains of the resilient controller. Finally, the simulation examples about single‐machine infinite‐bus power system are given to explain the effectiveness and feasibility of the proposed control approach.
Trend der Brückeneinstürze bei zunehmender Berichterstattung
Authors: Proske Dirk 
Published: November 2023

AbstractIn den letzten Wochen und Monaten erfolgten in den Tagesmedien vermehrt Berichterstattungen über Brückeneinstürze. Diese betrafen sowohl Einstürze von Brücken im Bau als auch Einstürze durch außergewöhnliche Einwirkungen wie Hochwasser, Blitzfluten, Anpralle oder Brände oder unter Verkehrsbelastung. Diese gehäufte Berichterstattung legt die Frage nahe, ob sich die Einsturzhäufigkeit von Brücken in diesem und im letzten Jahr erhöht hat. In diesem Beitrag wird der Versuch unternommen, diese Frage zu beantworten. Dazu werden sowohl bisherige Studien als auch aktuelle Prognosen zusammengefasst. Darüber hinaus erfolgt ein Vergleich der Daten der IABSE‐Einsturzdatenbank mit einer eigenen Datensammlung. Im Ergebnis kann man nicht bestätigen, dass die Einsturzhäufigkeit von Brücken gestiegen ist, vermutlich ist aber der seit Jahrzehnten zu beobachtende fallende Trend der Einsturzhäufigkeiten zum Stillstand gekommen.
Water contaminant: Use it but do not shield it to synthesize co‐polymers with multiple emission colours
Authors: Yang Yuan , Dong Fenghao , Qi Chunxuan , Lv Jiawei , Lu Huiming , Sun Yuqing , Zeng Cheng , Shen Richao , Lei Ziqiang , Ma Hengchang 
Published: November 2023

AbstractDue to the high affinity with water molecules, amide compounds are easily contaminated by moisture; therefore, the water interference effect cannot be totally excluded from the amide‐involved reactions. Thus, the perfect solution is to use the interference effect but not shield it in a real application. In this work, we introduced different contents of sodium acrylate (AAS) to scavenge water from the monomers of N‐isopropylacrylamide (NIPAm) when copolymerized with TPA‐Vinyl‐4CN. Herein, water molecules play a role as nucleophilic reagents to attack highly active functional groups as –C=C–CN from TPA‐Vinyl‐4CN, leading to a blue emissive TPA‐Vinyl‐2CHO. From this study, we made a deep awareness of the interactions between three reaction partners of AAS and NIPAm as well as TPA‐Vinyl‐4CN. Our results clearly demonstrated the fact that water can be perfectly used and controlled by the water absorbent of AAS, developing a new approach to synthesizing multiple emission‐coloured polymers by using only one luminogen of TPA‐Vinyl‐4CN.
Developing an ultra‐intensified fed‐batch cell culture process with greatly improved performance and productivity
Authors: Xiang Shaoxun , Zhang Jinliang , Yu Le , Tian Jun , Tang Wenxiu , Tang Hao , Xu Kecui , Wang Xin , Cui Yanyan , Ren Kaidi , Cao Weijia , Su Yuning , Zhou Weichang 
Published: November 2023

AbstractIntensified fed‐batch (IFB), a popular cell culture intensification strategy, has been widely used for productivity improvement through high density inoculation followed by fed‐batch cultivation. However, such an intensification strategy may counterproductively induce rapidly progressing cell apoptosis and difficult‐to‐sustain productivity. To improve culture performance, we developed a novel cell culture process intermittent‐perfusion fed‐batch (IPFB) which incorporates one single or multiple cycles of intermittent perfusion during an IFB process for better sustained cellular and metabolic behaviors and notably improved productivity. Unlike continuous perfusion or other semi‐continuous processes such as hybrid perfusion fed‐batch with only early‐stage perfusion, IPFB applies limited times of intermittent perfusion in the mid‐to‐late stage of production and still inherits bolus feedings on nonperfusion days as in a fed‐batch culture. Compared to IFB, an average titer increase of ~45% was obtained in eight recombinant CHO cell lines studied. Beyond IPFB, ultra‐intensified IPFB (UI‐IPFB) was designed with a markedly elevated seeding density of 20–80 × 106 cell/mL, achieved through the conventional alternating tangential flow filtration (ATF) perfusion expansion followed with a cell culture concentration step using the same ATF system. With UI‐IPFB, up to ~6 folds of traditional fed‐batch and ~3 folds of IFB productivity were achieved. Furthermore, the application grounded in these two novel processes showed broad‐based feasibility in multiple cell lines and products of interest, and was proven to be effective in cost of goods reduction and readily scalable to a larger scale in existing facilities.
Usage and impact of patient‐reported outcomes in epilepsy
Authors: Vonck Kristl , Biraben Arnaud , Bosak Magdalena , Jennum Poul Jørgen , Kimiskidis Vasilios K , Marusic Petr , Mitchell James W. , Ferreira Lara N. , Ondrušová Martina , Pana Adrian , Persson Ulf , von Oertzen Tim J. , Lattanzi Simona 
Published: November 2023

AbstractBackgroundThe use of patient‐reported outcomes (PRO) in clinical practice is gaining increasing attention. This study aimed to provide a critical assessment of the current state‐of‐the‐art and beliefs about the use of PRO in the management of people with epilepsy across some European countries.MethodsStructured interviews were conducted with European experts to collect insights about (I) the personal experience with PRO; (II) the value and impact of PRO in the decision‐making process at the national level; and (III) the interest for and use of PRO by national health authorities.ResultsNine neurologists (Austria, Belgium, Czechia, Denmark, France, Greece, Italy, Poland, and United Kingdom), three health economists (Portugal, Romania, and Sweden), and one epidemiologist (Slovakia) participated. They all stated that PRO are collected at their own countries in the context of clinical trials and/or specific projects. During everyday clinical practice, PRO are collected routinely/almost routinely in Austria and Sweden and only at the discretion of the treating physicians in Czechia, Denmark, France, Greece, and Portugal. There was complete consensus about the favorable impact that the PRO can have in terms of clinical outcomes, healthcare resources utilization, and general patient satisfaction. Only participants from Portugal and Sweden answered that the PRO are perceived as very important by the National Health Authorities of their respective countries.ConclusionsDifferences exist in attitudes and perspectives about PRO in epilepsy across Europe. An active plan is warranted to harmonize the measurement of PRO and ensure they can be relevant to people with epilepsy and health services.
Risks in circular business models innovation: A cross‐industrial case study for composite materials
Authors: Tuni Andrea , Gutteridge Fiona , Ijomah Winifred L. , Mirpourian Maryam 
Published: November 2023

AbstractCircular business models (CBMs) are key enablers to implement circular economy (CE), yet they entail risks, which often discourage organisations. This work aims to explore the main risk factors perceived by the manufacturing industry in transitioning to CBMs to enable the development of appropriate risk management strategies. A cross‐industrial multiple‐case study research design was used to explore risk factors across seven organisations planning the transition to CBMs for composite‐based products and involving three different CBM types—‘Circular Supplies’, ‘Product Life Extension’ and ‘Hybrid’. Results evidenced that risks are multi‐disciplinary but are not equally perceived across different CBM types. Customers' perceptions of CE products, economic cycle and take‐back systems were prevalent across all CBMs. Supply and technological risks were prioritised for ‘Circular Supplies’ CBM, whereas political and regulatory risks for ‘Product Life Extension’ CBM. This research contributes to the CE field by evaluating and prioritising the perceived risk factors in transitioning to CBMs and first disaggregating such risk factors according to CBM types. Critical risk patterns identified across different industries and CBM types enable mitigating actions to be prioritised.
Hydraulic conductivity of human cancer tissue: A hybrid study
Authors: Salavati Hooman , Pullens Pim , Debbaut Charlotte , Ceelen Wim 
Published: November 2023

AbstractBackgroundElevated tumor tissue interstitial fluid pressure (IFP) is an adverse biomechanical biomarker that predicts poor therapy response and an aggressive phenotype. Advances in functional imaging have opened the prospect of measuring IFP non‐invasively. Image‐based estimation of the IFP requires knowledge of the tissue hydraulic conductivity (K), a measure for the ease of bulk flow through the interstitium. However, data on the magnitude of K in human cancer tissue are not available.MethodsWe measured the hydraulic conductivity of tumor tissue using modified Ussing chambers in surgical resection specimens. The effect of the tumor microenvironment (TME) on K was investigated by quantifying the collagen content, cell density, and fibroblast density of the tested samples using quantitative immune histochemistry. Also, we developed a computational fluid dynamics (CFD) model to evaluate the role of K on interstitial fluid flow and drug transport in solid tumors.ResultsThe results show that the hydraulic conductivity of human tumor tissues is very limited, ranging from approximately 10−15 to 10−14 m2/Pa∙s. Moreover, K values varied significantly between tumor types and between different samples from the same tumor. A significant inverse correlation was found between collagen fiber density and hydraulic conductivity values. However, no correlation was detected between K and cancer cell or fibroblast densities. The computational model demonstrated the impact of K on the interstitial fluid flow and the drug concentration profile: higher K values led to a lower IFP and deeper drug penetration.ConclusionsHuman tumor tissue is characterized by a very limited hydraulic conductivity, representing a barrier to effective drug transport. The results of this study can inform the development of realistic computational models, facilitate non‐invasive IFP estimation, and contribute to stromal targeting anticancer therapies.
Evaluation of colposcopy after the addition of human papillomavirus testing to the Turkish cervical cancer screening program
Authors: Gunes Ali Can , Ozgul Nejat , Turkyılmaz Murat , Kara Fatih , Unlu Fahriye , Ayhan Ali , Gultekin Murat 
Published: November 2023

AbstractObjectiveTo evaluate colposcopy performance following the human papillomavirus (HPV) DNA screening program in Turkey.MethodsWomen aged 30–65 years are screened for cervical cancer every 5 years, with individuals positive for HPV 16 and/or 18 or other high‐risk HPV types with abnormal cytology referred for colposcopy. Both HPV test and cytology are obtained at the same visit. If HPV is negative, cytology will not be assessed. However, if HPV is positive, both cytology and HPV genotyping will be performed. Colposcopy‐require was defined as HPV 16/18 positivity or abnormal smear results with any hrHPV positivity, and the remaining patients (normal smear with hrHPV positivity other than HPV 16/18) were grouped as colposcopy non‐required. National data on colposcopy outcomes and unnecessary performance rates in February 2018–2019 were evaluated via a questionnaire.ResultsA total of 9808 patients were included, divided based on colposcopy requirement: 5751 (58.6%) patients required colposcopy and 4057 (41.4%) did not. Unnecessary colposcopy was performed on 90.1% of the non‐required group (3657 of 4057 patients). In the colposcopy‐required group, 4455 patients (79.9%) underwent punch biopsy; 3194 (57.1%), endocervical curettage (ECC); and 421 (7.5%), “see and treat” in the non‐required group, the results were 2790 (76.3%), 1957 (53.2%), and 211 (5.7%), respectively. A total of 746 cervical intraepithelial neoplasia (CIN)‐3 isolates were detected, including 702 using existing screening and triage with 94.1% sensitivity (702/746). Multiple biopsies were taken in 69.8% (n = 3110) of patients from the colposcopy‐required group and 63.7% (n = 1777) from the non‐required group. The ECC samples included 19 cervical cancers and 212 ≥CIN‐3 lesions in the colposcopy‐required group, and four cancers and 41 ≥CIN‐3 lesions in the non‐required group. The proportion of ≥CIN‐3 lesions detected by ECC only was 4.7% (35 of 746 ≥CIN‐3 lesions).ConclusionOur results showed high rates of unnecessary colposcopies, and a high percentage of multiple and random punch biopsies and ECC.
A novel nomogram and risk stratification for early metastasis in cervical cancer after radical radiotherapy
Authors: Liu Linying , Lin Jie , Deng Sufang , Yu Haijuan , Xie Ning , Sun Yang 
Published: November 2023

AbstractObjectThis study aimed to establish an effective risk nomogram to predict the early distant metastasis (EDM) probability of cervical cancer (CC) patients treated with radical radiotherapy to aid individualized clinical decision‐making.MethodsA total of 489 patients with biopsy‐confirmed CC between December 2018 and January 2021 were enrolled. Logistic regression with the stepwise backward method was used to identify independent risk factors. The nomogram efficacy was evaluated by using the area under the receiver operating characteristic curve (AUC), C‐index by 1000 bootstrap replications, etc. Finally, patients were divided into high‐ and low‐risk groups of EDM based on the cut‐off value of nomogram points.Results36 (7.36%) CC patients had EDM, and 20 (55.6%) EDM had more than one metastatic site involved. Age below 51 (OR = 2.298, p < 0.001), tumor size larger than 4.5 cm (OR = 3.817, p < 0.001) and radiotherapy (OR = 3.319, p < 0.001) were independent risk factors of EDM. For the nomogram model, C‐index was 0.701 (95% CI = 0.604–0.798), and 0.675 (95% CI = 0.578–0.760) after 1000 bootstrap resampling validations. The Hosmer–Lemeshow test demonstrated no overfitting (p = 0.924). According to the Kaplan–Meier curve of risk score, patients with high risk were more prone to get EDM (p < 0.001).ConclusionThis is the first research to focus on EDM in CC patients. We have developed a robust scoring system to predict the risk of EDM in CC patients to screen out appropriate cases for consolidation therapy and more intensive follow‐up.
Protect Jewish students from anti‐Semitism, discrimination
Authors: Lyerly Eric 
Published: November 2023

Earlier this year, the Office for Civil Rights published a fact sheet focused on how colleges and universities can protect students from discrimination related to “shared ancestry or ethnic considerations” (bit.ly/3iPfyZP). Campus Legal Advisor covered this fact sheet in depth in our March 2023 issue (bit.ly/48gwhdu).