bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Presence of Anti-TPO Antibodies Increase the Likelihood of
Post-I131 Hypothyroidism
Authors: Quataert Felix , Bravenboer Bert , Keyaerts Marleen , Andreescu Corina Emilia 
Published: November 2023

AbstractThe use of radioactive iodine in the treatment of hyperthyroidism is common
practice. However, a standardized treatment protocol with regard to radioactive
iodine treatment (RAI) remains subject to discussion. We retrospectively
analyzed 100 patient records. Patient diagnosis, age, gender, body mass index
(BMI), dose of radioactive iodine, thyroid size, the 24 h radioiodine
uptake (24 h RAIU) and protein bound iodine (PBI) were deducted, as well
as the use of antithyroid drugs prior to RAI. Biochemical parameters were
obtained, such as TSH, fT4, fT3, Anti-TPO, Anti-TG antibodies and thyroid
stimulating antibodies. After 5 years of follow-up, 46% of the patients
proved to be hypothyroid, whereas 8% of the patients were not cured
after one dose of RAI. One year after RAI, a larger proportion of patients with
a toxic nodule developed hypothyroidism compared to patients with a multinodular
goiter (MNG) (44.2% vs. 21.2%). Radioactive iodine dose, PBI,
RAIU, BMI, size of the thyroid gland, diagnosis, age and TPO-antibodies showed
statistically significant differences in the development of hypothyroidism.
Furthermore, thiamazole pretherapy was shown to be a predictor of
hypothyroidism, as well as a high PBI value, exhibiting a positive predictive
value of 85.2% when the PBI exceeded 0.16. We suggest a standardized
measurement of TPO-Ab’s to further determine their role in the
development of hypothyroidism after RAI. The empirical dosing regimen was very
effective, illustrating a 92% cure rate after 1 dose.
Total Synthesis of the Pyrrole Alkaloids Strychnuxinal and Strychnuxin
Authors: Reber Keith P. , Okwor Neechi F. , Gujarati Priyansh D. 
Published: November 2023

AbstractThe first asymmetric total syntheses of the fused-pyrrole alkaloids strychnuxinal and strychnuxin have been achieved in 6 and 7 steps, respectively, starting from commercially available (±)-4-chlorostyrene oxide. Key steps in the synthetic route include a regioselective epoxide opening, a reductive etherification sequence to form the central 1,4-oxazine ring, and a late-stage phenol synthesis using a mild palladium-catalyzed coupling reaction. Notably, the optimized synthetic sequence presented avoids the use of traditional protecting groups. Total synthesis of these two structurally related natural products confirmed both their constitution (via NMR and X-ray crystallography) and their absolute configuration (via optical rotation).
Zygmunt Grudziński, 1870–1929
Authors: Sudoł-Szopińska Iwona , Panas-Goworska Marta , Szczerbo-Trojanowska Małgorzata 
Published: November 2023

AbstractThis history page in the series “Leaders in MSK Radiology” is dedicated to the memory and achievements of Zygmunt Grudziński, Polish radiologist at the University of Warsaw and founder of the Polish Society of Radiology and Polish Radiological Review, the first radiology journal.
A Case of Uterine Fibroid Associated with Gallbladder Polyp Treated with Homoeopathy
Authors: Rath Padmalaya , Jain Shruti 
Published: November 2023

AbstractUterine fibroids are benign growths in female reproductive system. The presentation of uterine fibroid varies, if it is symptomatic; it may include abnormal uterine bleeding or abdominal pressure and heaviness distressing the patient both physically and mentally. A case of a female patient aged 45 years with prolonged uterine bleeding for 10 to 12 days and pain in lower abdomen for 1 year is reported here. Imaging study showed multiple uterine fibroids with grade II fatty liver and gallbladder polyps. Constitutional homoeopathic medicine Phosphorus was prescribed. This case report is an example of speedy recovery by homoeopathy as evident from decrease in symptoms (visual analogue score) and ultrasonography of abdomen report which shows not only the regression of fibroids but also disappearance of grade II fatty liver and gallbladder polyps within 2 months of treatment. Assessment of the causal attribution of the outcomes of this treated case to the homoeopathic intervention was done using Modified Naranjo Criteria and ‘definite’ association was found.
Translating harassment: cross cultural reconstruction of the feminist identity in translated fiction
Authors: Irshad Isra , Yasmin Musarat 
Published: November 2023

AbstractThe issue of the sexual harassment of women is often discussed in academic literature, but how this issue is dealt with translated works has rarely been investigated. Targeting this lacuna, this study analyses the construction of the identity of the sexually harassed woman in two selected translations of a single novel. It also investigates how the translators’ perspectival positions are reflected in the translated versions of the source text. Mastoor’s Urdu novel, Aangan, and its two English translations by Rockwell and Hussain were chosen and used a parallel corpus. NLTK is used for the extraction of frequencies and concordances from this corpus. The data are analysed through critical discourse analysis (CDA), while drawing upon the theoretical assumptions of feminist translation. Both translators used discursive and translation strategies according to their perspectival positions. Rockwell has treated the issue of sexual harassment with sensitivity, whereas Hussain has shown tolerance of it and romanticized this issue. The image of the harassed woman appears maintained or magnified in Rockwell’s text, in which feminist translation strategies of supplementing, hijacking, adding commentary, substituting, deleting, adding and intensifying discursive choices were found to be employed. However, Hussain presented the same gender ideology as the one found in the source text, at times, the image of harassment was found to be de-emphasized in the translated version. She has mainly used the translation strategies of literal translation, omission, and explicitness. Moreover, the discursive processes of foregrounding, mitigated linguistic choices, and nominalisation were also employed. The findings imply that both translated texts depict the translators’ subjectivity, where the Rockwell’s translation seems to highlight the image of sexual harassment of women in Pakistani society.
A 3D printed tensile testing system for micro-scale specimens
Authors: Choi Won June , Rudolf Christopher , Safari Hamid , Riyad M. Faisal , Kulak Maxwell , Yeom Junghoon , Kang Wonmo 
Published: November 2023

Mechanical property characterization of micro-scale material systems, such as free-standing films or small diameter wires (&lt;20 µm), often requires expensive, specialized test systems. Conventional tensile test systems are usually designed for millimeter scale specimens with the force sensing capability of &gt;1N while microdevice-based testers are intended for micro-/nano-scale specimens operating within a much smaller force range of &lt;10 mN. This disparity leaves a technology gap in reliable and cost-effective characterization methods for specimens at the intermediate scale. In this research, we introduce the cost-effective and all-in-one tensile testing system with a built-in force sensor, self-aligning mechanisms, and loading frames. Owing to the advantages of 3D printing technologies, the ranges of force measurement (0.001–1 N) and displacement (up to tens of millimeters) of our 3D printed tensile tester can be readily tailored to suit specific material dimension and types. We have conducted a finite element simulation to identify the potential sources of the measurement error during tensile testing and addressed the dominant errors by simply modifying the dimension/design of the loading frames. As a proof-of-concept demonstration, we have characterized fine copper (Cu) wires with 10–25 µm diameters by the 3D printed tensile tester and confirmed that the measured mechanical properties match with the known values of bulk Cu. Our work shows that the proposed 3D printed tensile testing system offers a cost-efficient and easily accessible testing method for accurate mechanical characterization of specimens with cross-sectional dimensions of the order of tens of micrometers.
Optimizing the regularization in size-consistent second-order Brillouin-Wigner perturbation theory
Authors: Carter-Fenk Kevin , Shee James , Head-Gordon Martin 
Published: November 2023

Despite its simplicity and relatively low computational cost, second-order Møller-Plesset perturbation theory (MP2) is well-known to overbind noncovalent interactions between polarizable monomers and some organometallic bonds. In such situations, the pairwise-additive correlation energy expression in MP2 is inadequate. Although energy-gap dependent amplitude regularization can substantially improve the accuracy of conventional MP2 in these regimes, the same regularization parameter worsens the accuracy for small molecule thermochemistry and density-dependent properties. Recently, we proposed a repartitioning of Brillouin-Wigner perturbation theory that is size-consistent to second order (BW-s2), and a free parameter (α) was set to recover the exact dissociation limit of H2 in a minimal basis set. Alternatively α can be viewed as a regularization parameter, where each value of α represents a valid variant of BW-s2, which we denote as BW-s2(α). In this work, we semi-empirically optimize α for noncovalent interactions, thermochemistry, alkane conformational energies, electronic response properties, and transition metal datasets, leading to improvements in accuracy relative to the ab initio parameterization of BW-s2 and MP2. We demonstrate that the optimal α parameter (α = 4) is more transferable across chemical problems than energy-gap-dependent regularization parameters. This is attributable to the fact that the BW-s2(α) regularization strength depends on all of the information encoded in the t amplitudes rather than just orbital energy differences. While the computational scaling of BW-s2(α) is iterative O(N5), this effective and transferable approach to amplitude regularization is a promising route to incorporate higher-order correlation effects at second-order cost.
First hyperpolarizability of the di-8-ANEPPS and DR1 nonlinear optical chromophores in solution. An experimental and multi-scale theoretical chemistry study
Authors: Bouquiaux Charlotte , Beaujean Pierre , Ramos Tárcius N. , Castet Frédéric , Rodriguez Vincent , Champagne Benoît 
Published: November 2023

The solvent effects on the linear and second-order nonlinear optical properties of an aminonaphtylethenylpyridinium (ANEP) dye are investigated by combining experimental and theoretical chemistry methods. On the one hand, deep near infrared (NIR) hyper-Rayleigh scattering (HRS) measurements (1840–1950 nm) are performed on solutions of di-8-ANEPPS in deuterated chloroform, dimethylformamide, and dimethylsulfoxide to determine their first hyperpolarizablity (βHRS). For the first time, these HRS experiments are carried out in the picosecond regime in the deep NIR with very moderate (≤3 mW) average input power, providing a good signal-to-noise ratio and avoiding solvent thermal effects. Moreover, the frequency dispersion of βHRS is investigated for Disperse Red 1 (DR1), a dye commonly used as HRS external reference. On the other hand, these are compared with computational chemistry results obtained by using a sequential molecular dynamics (MD) then quantum mechanics (QM) approach. The MD method allows accounting for the dynamical nature of the molecular structures. Then, the QM part is based on TDDFT/M06-2X/6-311+G* calculations using solvation models ranging from continuum to discrete ones. Measurements report a decrease of the βHRS of di-8-ANEPPS in more polar solvents and these effects are reproduced by the different solvation models. For di-8-ANEPPS and DR1, comparisons show that the use of a hybrid solvation model, combining the description of the solvent molecules around the probe by point charges with a continuum model, already achieves quasi quantitative agreement with experiment. These results are further improved by using a polarizable embedding that includes the atomic polarizabilities in the solvent description.
A new converb originating from the locative noun in Beserman
Authors: Usacheva Maria , Serdobolskaya Natalia 
Published: November 2023

Abstract
In Beserman, a new converb grammaticalizes from the possessive locative form of the locative noun in
(o)ń-ńig. We show that the constructions with the converb have a clausal structure, while the constructions
with the locative noun are mostly noun phrases, even if they include an indication of the agent and patient of the situation
encoded by the locative noun. Semantically, the two types of constructions are also different. In the converb constructions the
situations encoded by the main and the embedded clause must overlap, while with locative nouns this is not necessarily the case.
The temporal reference of locative nouns is habitual/iterative, while converbs often have episodic (non-habitual) interpretation.
The original locative noun denotes a reference to a fixed location where the situation usually takes place. In the constructions
with the converb this meaning is bleached and generalized as an action which takes place in any possible location.
Analytic expressions for quasinormal modes and grey-body factors in the eikonal limit and beyond
Authors: Konoplya R A , Zhidenko A 
Published: November 2023

Abstract
Although the WKB series converges only asymptotically and guarantees the exact result solely in the eikonal regime, we have managed to derive concise analytical expressions for the quasinormal modes and grey-body factors of black holes, expanding beyond the eikonal approximation. Remarkably, these expressions demonstrate unexpectedly strong accuracy. We suggest a comprehensive approach for deriving analytical expressions for grey-body factors and quasinormal modes at various orders beyond the eikonal approximation. Two cases are examined as examples: the Schwarzschild-de Sitter black hole and hairy black holes within the framework of Effective Field Theory. We have publicly shared a generic code that calculates analytical expressions for grey-body factors and quasinormal modes of spherical black holes.
Phase formation and electrical properties of reactively sputtered Fe1−x
O thin films
Authors: Evertz S , Nicolin N , Cheng N , Primetzhofer D , Best J P , Dehm G 
Published: November 2023

Abstract
Wüstite, Fe1−x
O, is a crucial phase for the transition to CO2-free steel manufacturing as well as promising for electrochemical applications such as water splitting and ammonia synthesis. To study the effect of interfaces in these applications, thin-film model systems with defined interfaces are ideal. Previous studies lack a description of the growth mechanism to obtain Fe1−x
O thin films. Here, we investigate the phase formation of metastable Fe1−x
O during reactive magnetron sputtering while systematically varying the O2/Ar flow ratio from 1.8% to 7.2% and the pressure–distance product between 3.5 and 7.2 Pa cm. If bulk diffusion is minimized, thin films containing 96 vol.% wüstite and 4 vol.% Fe as impurity phase were achieved. Therefore, the wüstite phase formation appears to be surface diffusion dominated. To reveal the influence of impurity phases in wüstite on the electrical resistivity, systematic electrical resistivity measurements while cooling in situ were performed for the first time. The electrical resistivity was lower than that of single crystals of the respective iron oxides. This is attributed to the formation of Fe-rich layers at the substrate-film interface, which serve as additional conduction paths.
Systematic study of fusion suppression and its dependency on projectile breakup threshold energy
Authors: Ali Sabir , Gull Muntazir , Kumar Kamal , Ahmad Tauseef , Rizvi I A , Agarwal Avinash , Ghugre S S , Ali R N , Khan Faizan 
Published: November 2023

Abstract
Measurements of the excitation function (EF) of the observed evaporation residues (ERs) populated in the 20Ne + 93Nb reaction at E
lab ≈ 91−145 MeV are carried out to explore the systematic of fusion suppression and its dependency on projectile breakup threshold energy, by employing the offline γ-ray detection method. The EF of the observed ERs populated through complete and/or incomplete fusion processes are analysed in the framework of statistical mode code PACE4. The fusion function, derived from the experimentally measured fusion cross section data, is compared with the universal fusion function (UFF) to estimate the degree of fusion incompleteness. Based on the observed results, an empirical formula is proposed to interrelate the degree of fusion suppression and breakup threshold energy of the incident projectile.
Hierarchical dynamic aggregation graph modeling of vibration for semi-supervised fault diagnosis of power transformer
Authors: Liu Xiaoyan , He Yigang 
Published: November 2023

Abstract
Power equipment fault diagnostics is a critical aspect of ensuring the stability of the power grid system. However, it presents substantial challenges in obtaining labeled data that is spatial-temporal, multi-scale, and multi-domain, low noise for effective fault analysis and diagnosis. To address this issue, we propose a novel approach called hierarchical dynamic aggregation graph (HDAG) modeling for self-supervised fault diagnosis of power transformers using vibration data. Firstly, HDAG focuses on modeling the spatial and temporal correlations within the fault vectors, before converting them into time–frequency images for visualization. Secondly, our proposed fault diagnosis approach, (comprising the ST-sparse swin-transformer and multi-domain transformer fusion module), is integrated into the methodology. The ST-sparse swin transformer incorporates soft threshold modules, enabling the retention of relevant information while discarding irrelevant information. The multi-domain transformer fusion is designed to utilize the intra-domain and inter-domain signal characteristics to achieve a comprehensive feature representation. Finally, we present case studies based on experimental data that demonstrate the feasibility and effectiveness of our approach. Comparative evaluations against eight state-of-the-art techniques validate the improved information representation and diagnostic capabilities of our recommended strategy.
Defect detection of glassivation passivation parts wafer surface with random texture and different brightness
Authors: Meng Chao , Hao Fei , Li Panyu , Shi Jinfei 
Published: November 2023

Abstract
Automatic defect detection for glassivation passivation parts (GPP) wafer surface becomes an extremely challenging task, due to the interference of random texture, disturbance of low-contrast pseudo defects within the image, and difference of different brightness between images. In this paper, we propose a novel defect detection scheme for GPP wafer surface with random texture and different brightness. First, an automatic segmentation method center expansion idea-based for the region of interest (ROI) of die image is presented to eliminate the interference from edge background and improve the efficiency of defect detection. Then, a feature point set extraction method based on adaptive gain and error diffusion is proposed so that the defect feature between images with different brightness can be highlighted by adaptive gain, and the candidate defect feature point set under random texture feature is able to be extracted by error diffusion. Finally, the density-based spatial clustering of applications with noise considering grayscale constraint (GC-DBSCAN) is designed to identify the true defect clusters from the candidate defect feature point set and accomplish the detection of various types of surface defects. Experimental results show that the proposed method can completely implement the extraction of crack and dirty defects and eliminate the false detection caused by random texture and different brightness, which is very efficient and superior to other methods.
Combined detection of SARS-CoV-2 neutralizing antibodies and specific IgG in plasma based on SERS magnetic sensor
Authors: Song Bailing , Wang Lei , Jiao Feiyan , Zhao Huixue , Liu Tingwei , Sun Shijiao , Zhou Hao , Li Jiutong , Li Xinxia 
Published: November 2023

Abstract
In this study, a surface-enhanced Raman spectroscopy (SERS) magnetic sensor is established based on SERS principle and magnetic separation technology, and a highly sensitive, simple and fast method for quantitative detection of neutralizing antibodies (nABs) and specific IgG of SARS-CoV-2 in plasma is established combined with immunoassay. Two kinds of Raman nanospheres (RNPs) with different characteristic Raman shifts are used as signal sources and coupled to ACE2 and anti-IgG (FC) antibodies respectively, and magnetic beads are coupled to RBD. The competitive relationship between ACE2 and nABs, the binding relationship between specific IgG and anti-IgG (FC) antibodies are determined. The results show that the concentrations of nABs and specific IgG in the range of 10–2000 ng ml−1 are well correlated with SERS response intensity, and the recoveries are both between 90%–110%, with good precision. Bilirubin and common anticoagulants have no interference on the detection results. This method is accurate, reliable, sensitive and does not require complex pre-treatment, and is expected to be used for simultaneous detection of nABs and specific IgG in plasma of SARS-CoV-2. It has guiding significance for the development and evaluation of vaccines and the formulation of individualized vaccination schedule.
A rapid element pressure field simulation method for transcranial phase correction in focused ultrasound therapy
Authors: Xu Peng , Wu Nan , Shen Guofeng 
Published: November 2023

Abstract
Transcranial focused ultrasound ablation has emerged as a promising technique for treating neurological disorders. The clinical system exclusively employed the ray tracing method to compute phase aberrations induced by the human skull, taking into account computational time constraints. However, this method compromises slightly on accuracy compared to simulation-based methods. This study evaluates a fast simulation method that simulates the time-harmonic pressure field within the region of interest for effective phase correction. Experimental validation was carried out using a 512-element, 670 kHz hemispherical transducer for four ex vivo skulls. The ray tracing method achieved a restoration ratio of 64.81% ± 4.33% of acoustic intensity normalized to hydrophone measurements. In comparison, the rapid simulation method demonstrated improved results with a restoration ratio of 73.10% ± 7.46%, albeit slightly lower than the full-wave simulation which achieved a restoration ratio of 75.87% ± 5.40%. The rapid simulation methods exhibited computational times that were less than five minutes for parallel computation with 8 threads. The incident angle was calculated, and a maximum difference of 6.8 degrees was found when the fixed position of the skull was changed. Meanwhile, the restoration ratio of acoustic intensity was validated to be above 70% for different target positions away from the geometrical focus of the transducer. The favorable balance between time consumption and correction accuracy makes this method valuable for clinical treatment applications.