bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minimizing the expected maximum lateness for a job shop subject to stochastic machine breakdowns
Authors: Zambrano-Rey Gabriel Mauricio , González-Neira Eliana María , Forero-Ortiz Gabriel Fernando , Ocampo-Monsalve María José , Rivera-Torres Andrea 
Published: October 2023

AbstractThis paper addresses a stochastic job shop scheduling problem with sequence-dependent setup times, aiming to minimize the expected maximum lateness. The stochastic nature is modeled by considering uncertain times between failures (TBF) and uncertain times to repair (TTR). To tackle this problem, a simheuristic approach is proposed, which combines a tabu search (TS) algorithm with Monte Carlo simulation. A total of 320 instances were used to conduct multiple experiments. Instances were generated with two distributions to study the behavior of stochastic TTR and TBF under log-normal and exponential distributions. Firstly, the performance of the simheuristic was evaluated for small instances by comparing it with the simulation of optimal solutions obtained with a mixed-integer linear programming (MILP) model. The simheuristic approach demonstrated an average improvement of around 7% compared to the simulation of MILP model solutions. Secondly, the simheuristic performance was evaluated for medium and large-size instances by comparing it with the simulation of the solutions obtained by the earliest due date (EDD) and process time plus work in the next queue plus negative slack (PT + WINQ + SL) dispatching rules. The results showed an average improvement of around 11% compared to EDD and 14% compared to PT + WINQ + SL. Furthermore, the results highlight that even when the two distributions have the same expected value and coefficient of variation, they can yield different expected maximum lateness values. This emphasizes the importance of precise distribution fitting when solving real cases to achieve effective scheduling performance.
Femmephobia Is a Uniquely Powerful Predictor of Anti-Gay Behavior
Authors: Hoskin Rhea Ashley , Blair Karen L. , Holmberg Diane 
Published: October 2023

AbstractThe current study explored a form of femmephobia (specifically, negative attitudes toward femininity in men) as a predictor of anti-gay behaviors among a sample of heterosexual men (N = 417). Additional predictor variables included hierarchical worldviews (i.e., social dominance orientation, right-wing authoritarianism, narcissism) and prejudicial attitudes (i.e., old-fashioned and modern homonegativity). Femmephobia emerged as a robust predictor, accounting for 23% of the variance in anti-gay behavior, surpassing the explanatory power (15%) of all other considered variables combined. Moreover, social dominance only predicted anti-gay behavior when femmephobia levels were high. Future research on discrimination and violence related to sexual identity and gender expression should incorporate femmephobia as a key predictive factor.
Practical Advice on Scientific Design of Freeze-Drying Process: 2023 Update
Authors: Tchessalov Serguei , Maglio Vito , Kazarin Petr , Alexeenko Alina , Bhatnagar Bakul , Sahni Ekneet , Shalaev Evgenyi 
Published: October 2023

Abstract
Objective
The purpose of this paper is to re-visit the design of three steps in the freeze-drying process, namely freezing, primary drying, and secondary drying steps. Specifically, up-to-date recommendations for selecting freeze-drying conditions are provided based on the physical–chemical properties of formulations and engineering considerations.

Methods and Results
This paper discusses the fundamental factors to consider when selecting freezing, primary drying, and secondary drying conditions, and offers mathematical models for predicting the duration of each segment and product temperature during primary drying. Three simple heat/mass transfer primary drying (PD) models were tested, and their ability to predict product temperature and sublimation time showed good agreement. The PD models were validated based on the experimental data and utilized to tabulate the primary drying conditions for common pharmaceutical formulations, including amorphous and partially crystalline products. Examples of calculated drying cycles, including all steps, for typical amorphous and crystalline formulations are provided.

Conclusions
The authors revisited advice from a seminal paper by Tang and Pikal (Pharm Res. 21(2):191-200, 2004) on selecting freeze-drying process conditions and found that the majority of recommendations are still applicable today. There have been a number of advancements, including methods to promote ice nucleation and computer modeling for all steps of freeze-drying process. The authors created a database for primary drying and provided examples of complete freeze-drying cycles design. The paper may supplement the knowledge of scientists and formulators and serve as a user-friendly tool for quickly estimating the design space.
Anti-oomycete activities from essential oils and their major compounds on Phytophthora infestans
Authors: Deweer Caroline , Sahmer Karin , Muchembled Jérôme 
Published: October 2023

AbstractBotanicals are various plant-based products like plant extracts or essential oils. Anti-fungal activities of selected essential oils were tested on the pathogen causing potato and tomato late blight (Phytophthora infestans). Tests to evaluate anti-oomycete activities of commercial essential oils and their major compounds were carried out in vitro in microplate in liquid media. Anti-oomycete activities on Phytophthora infestans strain were obtained from essential oils/major compounds: Eucalyptus citriodora/citronellal; Syzygium aromaticum (clove)/eugenol; Mentha spicata/D-Carvone, L-Carvone; Origanum compactum/carvacrol; Satureja montana (savory)/carvacrol; Melaleuca alternifolia (tea tree)/terpinen-4-ol, and Thymus vulgaris/thymol. As an active substance of mineral origin, copper sulfate was chosen as a control. All selected essential oils showed an anti-oomycete activity calculated with IC50 indicator. The essential oils of clove, savory, and thyme showed the best anti-oomycete activities similar to copper sulfate, while oregano, eucalyptus, mint, and tea tree essential oils exhibited significantly weaker activities than copper sulfate. Clove essential oil showed the best activity (IC50 = 28 mg/L), while tea tree essential oil showed the worst activity (IC50 = 476 mg/L). For major compounds, three results were obtained: they were statistically more active than their essential oils (carvacrol for oregano, D- and L-Carvone for mint) or as active as their essential oils sources (thymol for thyme, carvacrol for savory, terpinen-4-ol for tea tree) or less active than their original essential oils (eugenol for clove, citronellal for eucalyptus). Microscopical observations carried out with the seven essential oils showed that they were all responsible for a modification of the morphology of the mycelium. The results demonstrated that various essential oils show different anti-oomycete activities, sometimes related to a major compound and sometimes unrelated, indicating that other compounds must play a role in total anti-oomycete activity.
Cognitive Complaints and Their Impact on Daily Life in Patients with Degenerative Cerebellar Disorders
Authors: Reumers Stacha F.I. , Schutter Dennis J.L.G. , Maas Roderick P.P.W.M. , de Leeuw Frank-Erik , Kessels Roy P.C. , van de Warrenburg Bart P.C. 
Published: October 2023

AbstractCognitive and affective sequelae of cerebellar disease are receiving increased attention, but their actual rate of occurrence remains unclear. Complaints may have a significant impact on patients, affecting social behavior and psychological well-being. This study aims to explore the extent of subjective cognitive and affective symptoms in patients with degenerative ataxias in the Netherlands. An explorative study was set up in a heterogeneous group of degenerative ataxia patients. Self-reported cognition was evaluated in terms of executive functioning and affect (Dysexecutive Questionnaire/DEX), and memory/attention (Cognitive Failures Questionnaire/CFQ). The Daily Living Questionnaire (DLQ) was administered to quantify the impact on daily life. Furthermore, informants completed questionnaires to obtain insight into patients’ self-awareness and social cognition (Observable Social Cognition Rating Scale/OSCARS). This study shows that subjective complaints in the domains of (1) executive functioning and/or (2) memory and attention were reported by 29% of all patients (n = 24/84). In addition, more difficulties in daily life in terms of language/comprehension and community/participation were reported, and this was more common for patients with cognitive complaints than those without. Discrepancies between patients and informants about executive functioning were present in both directions. Deficits in social cognition were not identified at the group level, but more social-cognitive problems were observed in patients with more executive problems rated by informants. Taken together, our findings indicate that cognitive complaints are common in patients with degenerative cerebellar disorders and have an impact on daily life functioning. These results may help to increase awareness of cognitive symptoms and their impact in patients with cerebellar ataxia, their significant others, and professional caregivers.
Photodegradation of free base and zinc porphyrins in the presence and absence of oxygen
Authors: Golec Barbara , Buczyńska Joanna , Nawara Krzysztof , Gorski Aleksander , Waluk Jacek 
Published: October 2023

AbstractComparison of photostability in degassed and aerated toluene solutions is reported for 5,10,15,20-tetraphenylporphyrin, 5,10,15-tri(p-tolyl)porphyrin, and their zinc analogues. After degassing, quantum yields of photodegradation are higher, but the photodecomposition rates decrease. Lower stability in deoxygenated solutions is due to much longer triplet lifetimes: 200–300 microseconds, compared to 200–360 ns in non-degassed toluene. For the zinc porphyrins, the LC–MS results show that the initial photoproduct contains two oxygen atoms. Based on electronic absorption and calculations, it is assigned to dehydrated zinc biladienone structure, relatively stable in toluene, but readily demetallated in dichloromethane. A similar species is formed also in the case of free bases, but it then undergoes hydration due to traces of water present in the solvent. Zinc derivatives were found to form biladienones even in degassed solutions. To explain this observation, we postulate formation of a complex with remaining oxygen or oxygen-containing species which is not removed by freeze–thaw procedure. This hypothesis is confirmed by MS results and by the analysis of photodegradation products obtained when zinc porphyrin is complexed with dimethylsulfoxide (DMSO). Under these circumstances, changes in absorption are the same as in the absence of DMSO when non-degassed toluene is used, but irradiation of deoxygenated solutions leads to a different photoproduct. For both degassed and non-degassed solvents, complexation with DMSO results in the enhancement of photostability.
Graphical abstract
An accurate method for identifying hub dynamic loads by condition number of measured FRF matrix on helicopter fuselage
Authors: Shang L. , Wang E. , Xia P. 
Published: October 2023

AbstractIt is a simple method to identify the hub dynamic loads of rotor by measuring the vibration responses on helicopter fuselage. However, the identification accuracy of the hub dynamic loads is related to the layout or placement of measuring points on the fuselage. The identification will be inaccurate if the layout of measuring points on the fuselage is unreasonable to result in the “ill-conditioned” frequency response function (FRF) matrix measured on the fuselage. In order to avoid the inaccurate identification due to the “ill-conditioned” measured FRF matrix, an accurate method for identifying the hub dynamic loads of rotor by vibration measurement on helicopter fuselage is proposed in this paper. In the proposed method, the reasonable layout of the measuring points on the fuselage for the “well-conditioned” measured FRF matrix can be obtained according to the condition number of the measured FRF matrix on the fuselage, and then the hub dynamic loads of rotor can be accurately identified. The simulation and experiment of the identification of the hub dynamic loads on a dynamically similar frame structure of a helicopter cockpit floor have verified the effectiveness and accuracy of the proposed method.
The Relationship Between Constitutional Equality and Substantive Review
Authors: Chng Kenny 
Published: October 2023

AbstractGeneral equality rights in written constitutions – rights stating the ideal of equality without specifying categories of impermissible differentiation – have often been effected through the idea of equality as rationality. Equality as rationality demands that differentiations between like entities have to be rationally justifiable. Such equality rights are applicable to legislation and executive action. This presents a prima facie overlap with substantive review in common law administrative law, since substantive review is also concerned about the rational justifiability of executive action. This raises three questions: (1) Are both sets of legal principles indeed similar? (2) Have courts managed to distinguish them in practice? (3) If not, then given that both sets of legal principles exist at different levels in the legal order, how can their similarity be rationalised? This article will study these questions, drawing upon Hong Kong and Singapore law as test cases.
Mental health research in South America: Psychiatrists and psychiatry trainees’ perceived resources and barriers
Authors: Ramalho Rodrigo , Chappe Vanessa , Alvarez Lisette , Argomedo-Ramos Gianfranco C.A. , Rivera Arroyo Guillermo , Bonay Graciela L. , Libuy Mena Javiera C. , Cuellar Hoppe Miguel A. , Cevallos-Robalino Domenica N. , Gonzalez-Diaz Jairo M. 
Published: October 2023

Abstract
As mental health issues continue to rise in Latin America, the need for research in this field becomes increasingly pressing. This study aimed to explore the perceived barriers and resources for research and publications among psychiatrists and psychiatry trainees from nine Spanish-speaking countries in South America. Data was collected through an anonymous online survey and analyzed using descriptive methods and the SPSS Statistical package. In total, 214 responses were analyzed. Among the participating psychiatrists, 61.8% reported having led a research project and 74.7% of them reported having led an academic publication. As for the psychiatry trainees, 26% reported having conducted research and 41.5% reported having published or attempted to publish an academic paper. When available, having access to research training, protected research time and mentorship opportunities were significant resources for research. Further support is needed in terms of funding, training, protected research time and mentorship opportunities. However, despite their efforts to participate in the global mental health discussion, Latin American psychiatrists and psychiatry trainees remain largely underrepresented in the literature.
Association of dietary intake with micronutrient deficiency in Indian school children: a cross-sectional study
Authors: Awasthi Shally , Kumar Divas , Dixit Swati , Mahdi Abbas Ali , Gupta Barkha , Agarwal Girdhar G. , Pandey Anuj Kumar , Awasthi Avivar , A. R. Somashekar , Bhat Mushtaq A. , Kar Sonali , Mahanta B. N. , Mathew Joseph L. , Nair Suma , Singh C. M. , Singh Kuldeep , Thekkumkara Surendran Anish 
Published: October 2023

Abstract
Adequate nutrition is necessary during childhood and early adolescence for adequate growth and development. Hence, the objective of the study was to assess the association between dietary intake and blood levels of minerals (calcium, iron, zinc, and selenium) and vitamins (folate, vitamin B12, vitamin A, and vitamin D) in urban school going children aged 6–16 years in India, in a multicentric cross-sectional study. Participants were enrolled from randomly selected schools in ten cities. Three-day food intake data was collected using a 24-h dietary recall method. The intake was dichotomised into adequate and inadequate. Blood samples were collected to assess levels of micronutrients. From April 2019 to February 2020, 2428 participants (50⋅2 % females) were recruited from 60 schools. Inadequate intake for calcium was in 93⋅4 % (246⋅5 ± 149⋅4 mg), iron 86⋅5 % (7⋅6 ± 3⋅0 mg), zinc 84⋅0 % (3⋅9 ± 2⋅4 mg), selenium 30⋅2 % (11⋅3 ± 9⋅7 mcg), folate 73⋅8 % (93⋅6 ± 55⋅4 mcg), vitamin B12 94⋅4 % (0⋅2 ± 0⋅4 mcg), vitamin A 96⋅0 % (101⋅7 ± 94⋅1 mcg), and vitamin D 100⋅0 % (0⋅4 ± 0⋅6 mcg). Controlling for sex and socioeconomic status, the odds of biochemical deficiency with inadequate intake for iron [AOR = 1⋅37 (95 % CI 1⋅07–1⋅76)], zinc [AOR = 5⋅14 (95 % CI 2⋅24–11⋅78)], selenium [AOR = 3⋅63 (95 % CI 2⋅70–4⋅89)], folate [AOR = 1⋅59 (95 % CI 1⋅25–2⋅03)], and vitamin B12 [AOR = 1⋅62 (95 %CI 1⋅07–2⋅45)]. Since there is a significant association between the inadequate intake and biochemical deficiencies of iron, zinc, selenium, folate, and vitamin B12, regular surveillance for adequacy of micronutrient intake must be undertaken to identify children at risk of deficiency, for timely intervention.
War, Revolution, and Failed Democratization in Bolivia and Ecuador
Authors: Carrión Julio F. 
Published: October 2023

This essay reviews the following works:The FBI in Latin America: The Ecuador Files. By Marc Becker. Durham, NC: Duke University Press Books, 2017. Pp. vii + 322. $27.95 paperback. ISBN: 9780822369080.The CIA in Ecuador. By Marc Becker. Durham, NC: Duke University Press Books, 2021. Pp. xi + 317. $27.95 paperback. ISBN: 9781478011385.Movilidad y poder en el sur del Ecuador, 1950–1990. By María Mercedes Eguiguren. Quito: Editorial FLACSO Ecuador, 2019. Pp. viii + 274. Open access e-book. ISBN: 9789978675199.Peasant Wars in Bolivia: Making, Thinking, and Living the Revolution in Cochabamba (1952–64). By José M. Gordillo. Calgary: University of Calgary Press, 2022. Pp. xiv + 337. $34.99 paperback. ISBN: 9781773854014.A Concise History of Bolivia. 3rd ed. By Herbert F. Klein. New York: Cambridge University Press, 2021. Pp. xix + 380. $34.99 paperback. ISBN: 9781108948890.Indigenous Struggle and the Bolivian National Revolution: Land and Liberty. By James Kohl. New York: Routledge, 2021. Pp. xii + 413. $64.95 paperback. ISBN: 9780367471392.Historical Dictionary of Ecuador. By George M. Lauderbaugh. Lanham, MD: Rowman & Littlefield Publishers, 2019. Pp. xlviii + 322. $96.84 hardcover. ISBN: 9781538102459.¡Vamos a avanzar! The Chaco War and Bolivia’s Political Transformation, 1899–1952. By Robert Niebuhr. Albuquerque: University of New Mexico Press, 2021. Pp. xii + 260. $60.00 hardcover. ISBN: 9781496207784.Los inconformistas del Centenario: Intelectuales, socialismo y nación en una Bolivia en crisis (1925–1939). By Pablo Stefanoni. La Paz: Plural Editores, 2015. Pp. 383. ISBN: 9789995416430.The Bolivia Reader: History, Culture, Politics. Edited by Sinclair Thomson, Rossana Barragán, Xavier Albó, Seemin Qayum, and Mark Goodale. Durham, NC: Duke University Press, 2018. Pp. xx + 719. $35.95 paperback. ISBN: 9780822371526.
The trajectory of maternal perinatal depressive symptoms predicts executive function in early childhood
Authors: Power Josephine , Watson Stuart , Chen Wai , Lewis Andrew , van IJzendoorn Marinus , Galbally Megan 
Published: October 2023

AbstractBackgroundPerinatal maternal depression may affect fetal neurodevelopment directly or indirectly via exposures such as smoking, alcohol, or antidepressant use. The relative contribution of these risk factors on child executive function (EF) has not been explored systematically.MethodsA prospective pregnancy cohort of 197 women and their children was studied to determine whether maternal depression diagnosis and the trajectory of maternal depressive symptoms (MDSs) from early pregnancy to 12 months postpartum predicts child EF at age 4 (measured using the preschool age psychiatric assessment, NEPSY-II, and Shape School task) using latent growth curve modeling. Indirect effects of smoking, alcohol, and antidepressant use were also formally tested.ResultsIncreasing maternal perinatal depressive symptoms over time predicted more inattentive symptoms, poorer switching, and motor inhibition, but not cognitive inhibition. When adjusted for multiple comparison, and after accounting for maternal cognition and education, the association with child inattentive symptoms remained significant. However, diagnosed depression did not predict child EF outcomes. Prenatal exposure to smoking, alcohol, and antidepressants also did not mediate pathways from depressive symptoms to EF outcomes. Our findings were limited by sample size and statistical power to detect outcome effects of smaller effect size.ConclusionsThis study suggests that increasing MDSs over the perinatal period is associated with poorer EF outcomes in children at age 4 – independent of prenatal smoking, drinking, or antidepressant use. Depressive chronicity, severity, and postpartum influences may play crucial roles in determining childhood outcomes of EF.
A cognitive account of the puzzle of ideography
Authors: Arsiwalla Xerxes D. 
Published: October 2023

Abstract
We posit a cognitive account of the puzzle of ideography, which complements the standardization account of Morin. Efficient standardization of spoken language is phenomenologically attributed to a modality effect coupled with chunking of cognitive representations, further aided by multisensory integration and the serialized nature of attention. These mechanisms explain why languages dominate graphic codes for general-purpose communication.
Revisiting the social construction of old age
Authors: Gilleard Chris 
Published: October 2023

Abstract
The aim of this paper is to review the social constructionist view of age and ageing that emerged in the late 1970s and early 1980s. It begins with a general consideration of social constructionism as an epistemological framing of the world, before turning to its use in social gerontology. It considers two distinct social constructionist approaches treating later life as a social reality: (a) as a structural consequence of the rise of the modern state and its organisation of the labour market and (b) as a consequence of shifting cultural and social representations. Arguing that the earlier more structuralist accounts have gradually become overshadowed by concerns over age as identity, socially constructivist approaches now place as much emphasis upon the social representation of age as on its social-structural organisation. The paper then reviews the costs and benefits of social constructionism in general and its becoming a key part in the study of ageing. Its benefits arise from drawing attention to the salience of the cultural and the social in fashioning age and ageing and thereby advancing the sociology of later life. At the same time, social constructionist approaches to old age risk neglecting an other personal and social reality arising from corporeal decline and fear of the body-to-come. The paper concludes by noting how, whether approaching ageing and old age as natural kinds or as human kinds, adopting biological or sociological methodologies, all such methods privilege the externality of age – whether as a social or a biological fact. What is not captured by either is the problematic internality of age. What might be called the subjectivity of age will remain a topic for cultural representation, beyond the methods of both biological and social science.