bluuebunny/crossref_metadata_2025_split huggingface dataset:
LDL levels and ejection fraction in ischemic stroke patients: a hospital based cross-sectional study
Authors: Das Soumya K. , Raj A. Thomas Edwin , Jebasingh Y. Kingsly , Kannan B. , Pai Hrishikesh S. 
Published: December 2023

Background: Ischemic stroke is a top contributor to mortality amongst non-infectious diseases. Atherosclerosis is a major risk factor. This study aims to assess LDL levels and ejection fraction in ischemic stroke patients.
Methods: This descriptive cross-sectional study was conducted in Government Thoothukudi Medical College from November, 2022 to April, 2023. 35 patients admitted in the neuromedicine ward and diagnosed as acute ischemic stroke were included in the study after informed consent and ethical clearance. Patients with acute neurological deficit and evidence of infarct on diffusion-weighted MRI were included. Patients with no evidence of infarct on DWI, those already on lipid lowering therapy, patients with a history of cerebrovascular disease or transient ischemic attacks were excluded. Blood for lipid profile taken after 8 hours of overnight fasting. Echocardiography done for all patients.
Results: Of the 35 patients, 26 (74.28%) were men, mean age was 62.4. 57.14% ischemic stroke patients had their LDL levels elevated, 28.57% had decreased HDL, 28.57% had total cholesterol levels elevated, and in 14.28% triglycerides was elevated. This study also observed the cardiac status of the patients which showed 29% patients had decreased ejection fraction.
Conclusions: This study concluded that most patients had elevated LDL levels which is an independent risk factor of ischemic cerebrovascular disease. LDL levels were also associated with decreased ejection fraction in a significant number of patients. Thereby it can be concluded that elevated LDL cholesterol levels can add to the cardiac risk, potentially contributing to stroke morbidity and mortality.
A study of vitamin C, superoxide dismutase and FEV1/FVC ratio in chronic obstructive pulmonary disease
Authors: Mulani Manzura R. , Deshmukh Savita , Masaram Shrikant W. , Bhave Dilip 
Published: December 2023

Background: Chronic obstructive pulmonary disease (COPD) is a progressive lung disease characterized by incomplete reversible airflow limitation, which is associated with emphysema and chronic inflammation. Oxidative/antioxidant imbalance is one of the mechanisms of the current pathogenesis of COPD ECSOD is an antioxidant protein that scavenges superoxide free radicals from cigarette smoke and protects the lungs from free radical damage and chronic inflammation.
Methods: Vitamin C was estimated by acid phosphotungustate on spectrometer at 660nm (Ayekygw 1978) method. SOD was estimated by Marklund S and Marklund G (1974) modified by Nandi and Chatterjee. FEV1/FEV ratio was done by spirometry technique.
Results: The present study revealed that there was an increased oxidative stress in patients with COPD, when compared with controls and also decreased level of antioxidant activity in COPD patients, when compared with controls. In our studies significantly decreased sr. superoxide dismutase activity and FEV1/FVC ratio levels were found in subjects with COPD than healthy normal subjects.
Conclusions: A significant decline in lung function may be associated with altered antioxidant enzyme activity due to the strong correlation between SOD and lung functions with COPD severity.
Correlative study of sonological appearance of BI-RADS 4 and above breast lumps with histopathology and immunohistochemistry markers
Authors: Holla K. Vijaya Narayana , H. Tara , K. Veena 
Published: December 2023

Background: Breast cancer is clinically categorized into 4 major subtypes, ER (+), PR (+), Her2 (+), and TNBC. Although the correlation between sonographic features of breast cancer and immunohistochemistry markers expression is found, it is not still very clear; thus, this study aimed to investigate the ultrasound features of breast cancer and analyze the correlation between them.
Methods: This was a prospective study, in which patients with breast lumps were sonologically categorized as BI-RADS 4 and above. Percutaneous biopsy was done. Histopathology and immunohistochemistry markers were correlated with ultrasound findings.
Results: ER (+), PR (+) tumors were associated with irregular shape. ER (+), PR (+), and Her2 (+) tumors were associated with indistinct margin. TNBC tumor was associated with microlobulated margin. TNBC cases had more posterior acoustic enhancement.
Conclusions: Young female with ultrasound features of oval/round shape, micro-lobulated margin, abrupt tumor interface, showing posterior acoustic enhancement, absence of microcalcification was significantly associated with TNBC. Tumor with an irregular shape, indistinct margin, hyperechoic halo, no change in posterior acoustic feature, and presence of microcalcification were significantly associated with ER (+) cancers. Tumor with irregular shape, indistinct margin, and no change in the posterior acoustic feature was significantly associated with PR (+) cancers. Tumour with indistinct margin, and hyperechoic halo is significantly associated with Her2 (+) cancers. Tumor with irregular shape, indistinct margin, hyperechoic halo, and no posterior acoustic feature was associated with NTNBC.
Fetus in fetu: rare Indian case of infancy
Authors: Sharma Girraj Prasad , Chauhan Jagriti 
Published: December 2023

Fetus in fetu (FIF) is an extremely rare condition in which malformed twin develop inside the body of living twin. It is most commonly found within the retroperitoneum. Currently, at least 200 cases have been reported across the globe, yet very few instances seen in India. We describe a case of five months old infant born via normal vaginal delivery. She had a firm palpable mass measuring 7×10×7 cm in the left hypochondriac epigastric region crossing midline. A preoperative diagnosis of FIF was made by using ultrasonography (USG) and computed tomography (CT). An exploratory laparotomy and excision of mass was performed successfully. The excised mass was proven to be FIF on the basis of gross and histopathological examination. Even though teratoma is a differential diagnosis, surgical removal is the most suitable treatment method.
Evaluation of aprepitant as an add-on therapy for prevention of chemotherapy induced nausea and vomiting in children
Authors: Chowdhury Tapas , Karim M. Anwarul , Sultana Tania , Sharmin Farzana , Manik Zamil Ahmed , Ara Umme Nusrat , Akhter Sharmin , Akter Jesmine , Mou Farzana Alam 
Published: December 2023

Background: Chemotherapy-induced nausea and vomiting (CINV), represents a common and distressing side effect associated with antineoplastic treatment in pediatric patients. Aprepitant, a selective neurokinin-1 receptor antagonist, is recommended for preventing CINV in combination with a standard antiemetic regimen in children undergoing chemotherapy. This study aimed to evaluate the effectiveness of aprepitant as an add-on therapy to the standard antiemetic regimen for the prevention of CINV in children.
Methods: This randomized control study was conducted in the BSMMU, Dhaka, Bangladesh from February 2020 to October 2020. Forty-six children with malignancy undergoing chemotherapy were divided into two arms: the Aprepitant arm (23 patients receiving granisetron, dexamethasone, and aprepitant) and the control arm (23 patients receiving Granisetron and Dexamethasone). Data were analyzed using SPSS version 22.0.
Results: The complete response rates for the aprepitant versus control arm during the acute and overall phase were 82% vs. 40% (p=0.003) and 65% vs. 26% (p=0.008), respectively. However, a higher percentage of patients who achieved complete response in the delayed phase was also observed, though statistically not significant (65% vs 40%, p=0.077). In the acute phase, there was a significant reduction in mild to moderate vomiting in the Aprepitant arm as compared to the control arm (p=0.01). In the overall phase, 35% of patients in the Aprepitant arm had mild to moderate vomiting as compared to 74% in the control group (p=0.027). No major adverse effects were reported by patients or caregivers.
Conclusions: Adding Aprepitant to the standard antiemetic regimen was effective and safe in preventing CINV, especially in the acute phase, in pediatric patients receiving the moderately and highly emetogenic chemotherapy (HEC).
Interesting case of subglottic hemangioma presented with stridor
Authors: Patel Bhavya , Shah Binoy , Mehta Ashish , Mehta Abhijit , Shah Vaidehi 
Published: December 2023

Subglottic hemangioma is a very rare infantile form of hemangioma as compared to cutaneous hemangioma but if left undiagnosed or untreated can be life-threatening. Here we report one case of preterm who presented with sudden onset of inspiratory stridor and respiratory distress in OPD in a previously normal child. The patient was initially misdiagnosed as croup which did not improve after nebulized adrenaline and steroids later on direct laryngobrochoscopy showed subglottic stenosis. A CT scan was done later which revealed subglottic hemangioma which showed complete remission in symptoms after starting oral propranolol. A careful approach towards diagnosing and managing the sudden onset of stridor with probable structural cause is necessary for a favorable outcome.
A study of clinical, etiological demographic profile of patients with concomitant esotropia between ages 0-10 years
Authors: Kishore Arikeri Krishna , Ramdas Paspula , Chandrasekhar Bonu , Nelapatla Gopikrishna , Yenugandula Raman 
Published: December 2023

A study of clinical, etiological demographic profile of patients with concomitant esotropia between ages 0-10 years in a tertiary care hospital to assess various clinical patterns and refractive errors.It is a prospective observation study of patients with concomitant esotropia conducted at Sarojini Devi Eye Hospital, Hyderabad from September 2016 to March 2018. The study included 100 patients who attended the squint department, with chief complaints of inward deviation of eyes. A total of 100 patients were examined, 37 (37%) were of the 0-5 age group, and 63 (63%) were of the 6-10 age group. 41(41%) were male 59 (59%) were of female. 50 (50%) were from urban areas and 50 (50%) rural areas.The majority of the cases were of infantile esotropia 39 (39%) followed by Basic esotropia 34 (34%) sensory esotropia 12 (12%), accommodative esotropia 6 (6%), partially accommodative esotropia 5 (5%) and esotropia in myopia 4 (4%).Amblyopia was seen in 69 (69%) of cases which majority improved with amblyopia therapy. The most common refractive error was hypermetropia 76 (76%) and Myopia was seen in 24 (24%) of cases. AHP in 5.12% of cases, DVD in 15.38%, of cases, IOOA in (64.10%), DVD and IOOA in 10.25% of cases, manifest nystagmus in 10.25% of cases, manifest latent nystagmus in 5.12% of cases were seen.This study provides data on the most prevalent forms and associations of concomitant esotropia. Knowledge of various clinical types and timely intervention will help in the development of binocular single vision.
Family perceptions and barriers towards rehabilitation of visually disabled people: A qualitative survey from Western Uttar Pradesh
Authors: Singh Mahendra , Radhika  , Khurana Ashi , Chauhan Lokesh 
Published: December 2023

Looking at the number of visually disabled people population of Uttar Pradesh, there has been a paucity of evidence available on their perception and rehabilitation. This study was conducted to explore the perceptions and possible barriers to the uptake of visual rehabilitation services among visually disabled patients and their families in western Uttar Pradesh.A qualitative investigation using one-to-one interviews with the convenience sampling method in the subjects severely visually disabled (Blind) participants, and their family members. The unstructured interviews were conducted by an independent interviewer. All the interviews were conducted in Hindi. The anonymous quotes of transcripts were translated into English for reporting purposes.A total of 32 interviews were conducted. 16 Participants were between 12 to 52 years of age. Parents of participants who were less than 18 years of age were present during the interview. For the rest 16 patients below 10 years of age, interviews were conducted with their parents. The discussion of each interview was transcribed. The interviews ranged in length from 12 to 30 minutes. From content analysis, four main themes were identified. They are; 1) the denial phase of parents, 2) over protective families, 3) social stigma, and 4) awareness of rehabilitation services, training centers, and government policies in communities. While the majority (95%) were aware of railway discounts many participants had not been aware of other welfare schemes run by the state government. Only 15% had heard of rehabilitation services in the state and vocational training facilities.This study highlights three major challenges in the rehabilitation of visually disabled people in western Uttar Pradesh: 1) The availability of rehabilitation services in the study area, 2) The awareness of visually disabled people about these services, and, 3) The robust strategy for creating awareness about these services at the community level.
Portret polskich superbohaterów w obrazie Jana Komasy Miasto 44
Authors: Sosnowska Joannav 
Published: December 2023

Artykuł przestawia problematykę portretu filmowego jako elementu konstrukcji dzieła filmowego i kreacji bohatera. Kolejne dziedziny sztuki, w ramach których rozwija się portret, oferują nowe środki i możliwości opowiadania o postaci (bohaterze). Silnym elementem tworzącym konstrukt dzieła filmowego jest portret zarówno w wymiarze formalnym, jak I psychologicznym. Podjęte badania łączą analizę portretu filmowego ze współczesną tendencją gatunkową w kinematografii, jakim jest kino komiksowe i superbohaterskie. Jan Komasa stworzył nowoczesny, eklektyczny obraz wydarzeń historycznych w filmie Miasto 44 o Powstaniu Warszawskim, łącząc konwencję filmów o superbohaterach z opowieścią historyczną, odtwarzającą autentyczne wydarzenia II wojny światowej. Poprzez analizę elementów sztuk plastycznych (m.in. kompozycji, kolorystyki, perspektywy, stosunkach światła i cienia) oraz elementów filmowych (takich jak muzyka i dźwięk, ruch, montaż i zastosowanie efektów specjalnych) udało się ukazać inspiracje kinem superbohaterskim oraz wskazać na możliwości portretu w oddawaniu psychicznych i fizycznych cech bohaterów.
Chrystus samoobjawieniem Boga
Authors: Góźdź Krzysztof 
Published: December 2023

Bóg, sam w sobie ukryty i tajemniczy, nie pozostaje ukryty na wieki za obłokiem obrazów, które bardziej Go zasłaniają, niż ukazują, lecz również objawia się i ujawnia tajemnice swojej woli. Bóg zatem czyni siebie widzialnym, słyszalnym, zrozumiałym i bliskim nam poprzez ludzi, w których działa w Jego wychodzeniu do świata i tworzeniu dziejów zbawienia. W sposób ostateczny i pełny objawił się Bóg w swoim wcielonym Synu, który jako współistotny Ojcu jest jednocześnie Jego praobrazem. W ten sposób Jezus Chrystus jest samoobjawieniem Boga Ojca, który przez Syna w Duchu Świętym udziela się człowiekowi, otwierającemu się w wierze na Niego. Autor tekstu proponuje spekulatywną drogę wyrażenia prawdy samoobjawienia się Boga przez zastosowanie takich pojęć, jak: Chrystokształtność, samoudzielanie się Boga, posłannictwo Mesjasza i formułę „Ego-eimi”.
Eklezjologia sponsa Christi — odpowiedź na współczesne kryzysy Kościoła?
Authors: Lekan Janusz 
Published: December 2023

Kościół jest tą rzeczywistością wiary, która chyba najmocniej bywa interpelowana przez współczesny świat. Sobór Watykański II, nawiązując do biblijnych obrazów Kościoła, nie wskazał żadnego typu eklezjologii jako przewodniego. Autor bada w artykule eklezjologię sponsa Christi, temat mało podejmowany we współczesnej teologii. Wskazuje na jego bogactwo biblijne i patrystyczne. Proponuje ten typ eklezjologii jako realizację eklezjologii soborowej (powrót do źródeł biblijnych i patrystycznych) oraz jako pomoc w przezwyciężeniu kryzysów tożsamości chrześcijanina (sakrament małżeństwa, sakrament święceń, brak myślenie eschatologicznego, rozumienie grzechu).
ПРОФЕСІЙНО ВАЖЛИВІ ЯКОСТІ МАЙБУТНЬОГО ФАХІВЦЯ З МІЖНАРОДНОГО ПРАВА
Authors: Ладогубець Наталія 
Published: December 2023

У статті проаналізовано сутність і теоретичні засади поняття «професійно важливі якості майбутнього фахівця з міжнародного права» з урахуванням сучасних професійних вимог до майбутніх фахівців. Мета статті полягає в аналізі наукового визначення поняття «професійно важливі якості майбутнього фахівця з міжнародного права». Проаналізовано ряд вітчизняних і зарубіжних наукових, науково-публіцистичних джерел, у яких особливу увагу приділено поняттю «професійно важливі якості». З використанням методів наукового пізнання: теоретичних (вивчення, аналіз, синтез, порівняння, узагальнення наукової літератури з проблеми дослідження, систематизація і узагальнення отриманих даних), що дали змогу з’ясувати ряд питань як теоретичного, так і методологічного характеру стосовно професійно важливих якостей майбутніх фахівців з міжнародного права із урахуванням особливостей сучасного етапу розвитку суспільства.
Результати дослідження, проведеного на основі теоретичного осмислення наукових праць, визначено поняття «професійно важливі якості майбутнього фахівця з міжнародного права» показали, що проведений теоретико-методологічний дискурс поняття «професійно-важливі якості майбутніх фахівців з міжнародного права» є комплексом особистісних властивостей, індивідуальних психофізіологічних і соціально важливих якостей, які сприяють успішному виконанню майбутньої професійної діяльності, розв’язанню складних спеціалізованих завдань з багатовекторною невизначеністю, особистісно-професійному зростанню й удосконаленню
ОСОБИСТІСНИЙ РОЗВИТОК ТА ПРОФЕСІЙНЕ СТАНОВЛЕННЯ СТУДЕНТА В ОСВІТНЬО-ІНФОРМАЦІЙНОМУ СЕРЕДОВИЩІ ЗАКЛАДІВ ВИЩОЇ ОСВІТИ: РЕФЛЕКСИВНИЙ ПІДХІД
Authors: Лузік Ельвіра , Семиченко Валентина , Селезень Анна 
Published: December 2023

Стаття присвячена розгляду актуальності проблеми особистісного розвитку та професійного становлення студента як суб’єкта своєї життєдіяльності, який здатний критично аналізувати стан організації процесу навчання і професійної підготовки у закладі вищої освіти; визначати напрямки його оптимізації; усвідомлювати ступінь власної активності у професійній підготовці; оцінювати взаємовідносини між викладачами і студентами з позицій професійно-розвивальної доцільності.
Мета статті полягає в аналізі світових тенденцій особистісного росту та професійного становлення студента, що дозволить обгрунтувати необхідність організації освітнього процесу у закладі вищої освіти (ЗВО) на студентоцентрованій основі. Це зумовило необхідність проведення комплексних досліджень з виявлення, на рефлексивній основі, думок студентів щодо науково-методичних проблем організації навчального процесу у ЗВО; їх залучення до виявлення основних психолого-педагогічних проблем у викладацькій діяльності; визначення перспектив розвитку вищої професійної освіти.
Результати дослідження підтвердили доцільність врахування виявлених соціально-психологічних факторів і тенденцій у суспільстві, які супроводжуються стресами та конфліктами. Твердження, що ефективність of-line, on-line та змішаного режимів освітнього процесу у ЗВТО може бути значно оптимізована за умови врахування отриманого у процесі дослідження емпіричного матеріалу, доведено результатами педагогічного експерименту у відповідному освітньому інформаційному середовищі (ОІС) Національного авіаційного університету, про що свідчить проведене анкетування з використанням мультимедійних технологій в процесі викладання курсів циклу професійної підготовки майбутнім фахівцям.
Зроблений висновок щодо обґрунтування механізму врахування думок студентів відносно науково-методичних проблем організації освітнього процесу у ЗВО значною мірою підвищить якість викладання, ефективність сприйняття та засвоєння інформації студентами
TRAINING AIR TRANSPORT TECHNOLOGIES SPECIALISTS: FOREIGN EXPERIENCE
Authors: Akmaldinova Oleksandra , Akmaldinova Viktoriia , Volkovska Hanna 
Published: December 2023

The article is devoted to analysing the system of professional training of future specialists in air transport technologies in foreign higher technical education experience. The purpose of the article is to highlight the peculiarities of foreign experience in the formation of future aviation industry engineers professional competences under the influence of scientific and technical progress. Examples of aviation specialists theoretical and practical training in higher education institutions of the USA, Great Britain and the member-states of the European Union based on the use of innovative problem-oriented, distance and mixed learning methods, fruitful cooperation with stakeholders, taking into account the autonomy of educational institutions and the educational system flexibility are given.
Theoretical and empirical methods of comparative and generalizing analysis of different level academic programs (Bachelor’s & Master’s) and aviation specialists training experience have been used in the research.
Results.The system of the USA future pilots professional training effectively combines theoretical and practical types of activities, intensive use of computer technologies in the training process significantly improving its quality and effectiveness. According to the bachelor's and master's programs in aeronautical engineering presented by Great Britain higher technical education institutions, the training content involves an in-depth study of the flight practice basics and subjects of the professional orientation. The professional training of future specialists in air transport technologies in higher educational institutions of Germany is focused on integrated studying, practical training, internships and advanced training in airlines. The analysis of the international experience of future specialists in air transport technologies professional training shows that the characteristic features of training are the mandatory combination of theory and practice, with special emphasis on the professionally-oriented subjects in educational and professional programs, academic curricula, sufficient number of training hours for practice and internship in order to increase the future specialists competitiveness and attract experienced aviation experts to participate in the educational process.
Conclusion. Thus, it was concluded that in higher technical education institutions of EU member states (Germany, France, Poland), USA and Great Britain, the content of future specialists in air transport technologies professional training is based on the relevant educational standards implemented in educational and professional training programs involving the inclusion of practice-oriented academic subjects. It should be noted that the educational process of training air transport technologies specialists in higher technical education institutions of foreign countries is based on the application of traditional and rationalistic models as well as the developmental training model.