bluuebunny/crossref_metadata_2025_split huggingface dataset:
Portable non‐enzymatic electrochemical biosensor based on caffeine for Alzheimer's disease diagnosis
Authors: Zhang Xindan , Wang Audrey , Wang Chaojie , Tang Xiaoying , Jiang Zhenqi , Qin Jieling 
Published: October 2023

AbstractCaffeine and its derivatives can effectively bind amyloid beta 16–22 (Aβ16–22) fragment of amyloid beta 1–42 (Aβ1–42), a biomarker for the early diagnosis of Alzheimer's disease (AD), by means of conformation selection, π–π stacking, van der Waals forces, and hydrogen bonding, so as to achieve high specificity and quantitative detection of Aβ1–42. In this study, 3‐mercaptopropionic acid (MPA), conductive polymer poly(thiophene‐3‐acetic acid) (PTAA), and pine‐like/Au pine PTAA (pine PTAA) were applied to modify the electrodes, and the non‐enzymatic caffeine was used as specific biorecognition element to study the analytical performance of the electrochemical sensor platform for Aβ1–42 oligomer (AβO). It was found that caffeine/pine PTAA‐based sensor with large surface area, high active sites, and excellent electrical conductivity demonstrated the widest linear range (10−8 to 100 nM) and highest sensitivity (743.77 Ω/log nM) in comparison. The prepared caffeine‐based sensor was afterward applied to cerebrospinal fluid and blood tests for real sample analysis, demonstrating its potential for practical use in detecting AβO at the attomolar level. Furthermore, the non‐enzymatic caffeine was constructed on the pine‐like PTAA‐modified screen‐printed electrodes for the rapid detection of AβO using portable meter.
Optimization of stabilized anaerobic landfill leachate treatment using ozonation with metallic compound using response surface methodology
Authors: Zakaria Siti Nor Farhana , Aziz Hamidi Abdul , Mohamad Maheera , Mohamad Habib Musa , Sulaiman Mohd Fauzy 
Published: October 2023

AbstractMalaysia encounters a consistent rise in the generation of solid waste and leachate on a daily basis. It should also be noted that leachate has a low degree of biodegradability (BOD5/chemical oxygen demand [COD]), as shown by its BOD5/COD ratio. Its high toxicity levels significantly threaten the environment, water bodies, and human well‐being. High concentrations of COD, color, and ammoniacal nitrogen (NH3‐N) in leachate prevent this wastewater from being allowed to be discharged directly into the water body. Therefore, an effective process to remove the pollutant is desired. The aims of this study are to investigate the performance of ozonation with two metallic compounds, ZrCl4 and SnCl4, and optimize their performance using response surface methodology (RSM). In this study, the performance of ozonation with ZrCl4 (O3/ZrCl4) recorded better pollutant removals compared with the ozonation with tin tetrachloride (O3/SnCl4), as seen in the removals of 99.8%, 93.5%, and 46.3% for color, COD, and NH3‐N, respectively. These removals were achieved by following the experimental model (optimum experiment condition) generated by RSM at O3 dosage of 31 g/m3, COD and ZrCl4 dosage ratio (COD, mg/L/ZrCl4, mg/L) of 1:1.35, with the pH solution of 8.78 and reaction time of 89 min. The R2 of each parameter for this model was recorded as 0.999 (COD), 0.999 (color), and 0.998 (NH3‐N), respectively. These data indicated that the model is well fitted as the predicted data by statistical calculation and in good agreement with the actual data.Practitioner Points
The performance of O3/ZrCl4 and O3/SnCl4 was examined for remediate stabilized landfill leachate.
The performance of O3/ZrCl4 and O3/SnCl4 was optimized using RSM, and a set of experimental models was generated and tested.
O3/ZrCl4 recorded the higher removal of COD, color, and NH3‐N compared with O3/SnCl4.
At best condition, both methods recorded removal as 89% to 99.8% of pollutants in leachate and product clear effluent.
This finding gives a new approach to treat landfill leachate effectively and efficiently.
Leadership education as democracy‐in‐action: In pursuit of the United Nations Sustainable Development Goals
Authors: LeBlanc Julie , Odegard Stine 
Published: October 2023

AbstractWith the world growing in complexity and interconnectedness, the demand for leaders equipped to solve compound problems will only increase. Higher education is called upon to develop leadership in students and needs to engage relevant tools and techniques to prepare students for the tasks ahead. Democratic engagement—from voter education and engagement to critical service learning—and leadership development are powerful vehicles for student development. The United Nations Sustainable Development Goals are effective and compelling tools to support student learning in academic and cocurricular arenas as part of democratic engagement and leadership education and development. The authors will explore some of the implications and considerations in advancing these initiatives and using these means to advance our local and global communities.
Leadership and the regenerative economy ‐ Concepts, cases, and connections: Leveraging the Sustainable Development Goals to move toward sustainability leadership
Authors: Balda Janis Bragan , Stanberry Joanna , Altman Barbara 
Published: October 2023

AbstractHow leadership is taught and applied must take into account the complexities of socio‐ecological systems, the opportunities found in diverse viewpoints, the ability to parse conflict and power differences, and the ability to resource expert knowledge for more sustainable futures. We discuss and chart resources linked to leadership concepts critical to constructively harness business engagement with the Sustainable Development Goals (SDGs), identifying eight that are primary to active learning and application: systems resilience, strength through interdependence, scaling adaption, innovation for transformation, context and collectiveness, diversity of learning, negotiating power, and elevating the normative nature of the Global Goals.
From Romantic Advances to Cyberstalking in the Field
Authors: Dall’Agnola Jasmin 
Published: October 2023

AbstractSo far, the implications of sexual advances and cyberstalking on fieldworkers’ personal and professional lives have been rarely discussed in published form. While collecting data for my postdoctoral project in Central Asia, I experienced various forms of sexual harassment, ranging from unwelcomed sexual verbal and physical advances, whistling and catcalling to stalking both off- and online. In being honest and transparent about my personal experiences with unwanted sexual advances in the field, I neither wish to draw generalisations about Central Asian men, nor to discourage other female scholars from conducting fieldwork in the region. By contrast, I hope that my personal reflections will help other researchers mitigate and avoid similar situations.
Pitfalls and Promise for Public Opinion Research in Central Asia
Authors: Ysmanova Kasiet 
Published: October 2023

AbstractThe Central Asia Barometer (CAB) is one of the most active opinion polling institutions in Central Asia. It conducts large-scale surveys in all countries of Central Asia, including Turkmenistan. As the director of CAB, I coordinate the groups’ various research initiatives, ranging in methodology from phone polls to in-person interviews and focus groups with experts and the wider public. In discussing some of the challenges that my team and I face when collecting public opinion data, I seek to offer useful tips and recommendations for organisations and researchers that plan to conduct public opinion research in Central Asia.
‘Swiping Right’—The Ethics of Using Tinder as a Recruitment Tool in the Field
Authors: Sorbello Paolo 
Published: October 2023

AbstractThis article delves into the risks and pitfalls of using dating apps as participant recruitment tools in the field. To source people who worked in Kazakhstan’s oil industry for my Ph.D. research in 2018, I made use of various popular social media apps such as Facebook and LinkedIn as well as the dating app Tinder. In an effort to “normalise” heterodox recruiting methods, in this essay, I seek to openly discuss how Tinder helped me recruit women working in the oil sector who, under less informal circumstances, would not have agreed to talk to me for my research.
The Power of a Multi-layered Identity in Central Asian Research
Authors: Gafu Gulzhanat 
Published: October 2023

AbstractConducting research in the Central Asian context is complex due to the competing historical, cultural, and linguistic narratives of the past(s) and present(s). In this essay, I, as a female Kazakh scholar, discuss how various aspects of my multi-layered positionality (e.g., gender, social status, motherhood, and institutional affiliation) shape my research in/on Central Asia. While critically reflecting on my insider versus outsider position, I also touch on my positionality as a single mother of three underaged children and how this influences the way I experience fieldwork.
Navigating Academic Repression in Central Asia
Authors: Norov Ruslan 
Published: October 2023

AbstractWhile much has been written about the risks facing foreign researchers conducting fieldwork under the “watchful eyes” of the local authorities in Central Asia, personal accounts by local scholars are less common. In this chapter, I reflect on attempts by the local organs to suppress and silence my voice, as well as to recruit me to spread government propaganda. While doing so, I examine the various state-led threats to academic freedom and researcher safety. I also discuss how these threats have affected my ability to conduct research and what others can do to avoid or manage them.
The Historian as Pedagogue: On Hayden White’s Practical Past
Authors: Low Remy Y. S. 
Published: October 2023

AbstractWith all the panic about how the contemporary political and media landscape is awash with ‘fake news’, and the attempted response to that through fastidious ‘fact checks’, the late Hayden White’s lifelong exhortation to consider history as stories crafted by historians using fragments of the past must surely seem untimely. In his final scholarly intervention, White doubles down on this line, urging historians to consider practical uses of the past beyond the cloistered confines of disciplinary History (with a big ‘H’). Drawing on my experiences as a teacher in higher education, I want to show how practical pasts are regularly constructed: we are always selecting from fragments, stringing together facts, amplifying dramatic scenes, and muting minutiae. In other words, given the constraints of time and space—not to mention attention spans and working memory—teaching obliges us to treat the past in a practical manner.
How We Use Social Theory: Common Threads and Concluding Thoughts
Authors: Bell Amani 
Published: October 2023

AbstractIn this concluding chapter, I draw together the central themes and ideas to emerge in how each contributor has put social theory to work to make sense of aspects of our endeavours in higher education. I noticed four common threads: (1) Theory is personal and contextual; (2) What theory does; (3) Grappling; and (4) The collective individual. These are expanded on in this chapter, followed by a brief discussion of topics you may wish to explore beyond the book and some final reflections.
The Decolonial Imperative—Text and Context: A Response to Amani Bell and Gulwanyang Moran
Authors: Towers Lorraine 
Published: October 2023

AbstractResearch is not innocent, Linda Tuhiwai Smith tell us (2013). As a critical form of knowledge production about Indigenous people, research has been forged in the body of imperialism and the practice of colonialism and must now be the object of decolonisation. The revealing responses to this work of two contemporary academics, one Indigenous (Gulwanyang Moran) and one non-Indigenous (Amani Bell), have elicited my reflections on the significance of this work being understood through our subjectivities and everyday lives amidst the broader socio-political context. This contemplation has drawn me to consider how this work was both produced out of and through dynamic contexts of Indigenous resistance and activism, weaving through lives, thoughts and experiences, of those within and outside of the academy. My particular position as a settler, non-Indigenous academic in Aboriginal Education at a time of Aboriginal and Torres Strait Islander challenge to the coloniality of research and education becomes the prism through which I explore the limits of my initial reading of the work and the ongoing imperative of decoloniality in the institutions of research and education.
Interplay among gravitational waves, dark matter and collider signals in the singlet scalar extended type-II seesaw model
Authors: Ghosh Purusottam , Ghosh Tathagata , Roy Subhojit 
Published: October 2023

Abstract
We study the prospect of simultaneous explanation of tiny neutrino masses, dark matter (DM), and the observed baryon asymmetry of the Universe in a Z3-symmetric complex singlet scalar extended type-II seesaw model. The complex singlet scalar plays the role of DM. Analyzing the thermal history of the model, we identify the region of the parameter space that can generate a first-order electroweak phase transition (FOEWPT) in the early Universe, and the resulting stochastic gravitational waves (GW) can be detected at future space/ground-based GW experiments. First, we find that light triplet scalars do favor an FOEWPT. In our study, we choose the type-II seesaw part of the parameter space in such a way that light triplet scalars, especially the doubly charged ones, evade the strong bounds from their canonical searches at the Large Hadron Collider (LHC). However, the relevant part of the parameter space, where FOEWPT can happen only due to strong SM doublet-triplet interactions, is in tension with the SM-like Higgs decay to a pair of photons, which has already excluded the bulk of this parameter space. On the other hand, the latest spin-independent DM direct detection constraints from XENON-1T and PANDA-4T eliminate a significant amount of parameter space relevant for the dark sector assisted FOEWPT scenarios, and it is only possible when the complex scalar DM is significantly underabundant. In short, we conclude from our analysis that the absence of new physics at the HL-LHC and/or various DM experiments in the near future will severely limit the prospects of detecting a stochastic GW at future GW experiments and will exclude the possibility of electroweak baryogenesis within this model.
Symmetries for the 4HDM: extensions of cyclic groups
Authors: Shao Jiazhen , Ivanov Igor P. 
Published: October 2023

Abstract
Multi-Higgs models equipped with global symmetry groups, either exact or softly broken, offer a rich framework for constructions beyond the Standard Model and lead to remarkable phenomenological consequences. Knowing all the symmetry options within each class of models can guide its phenomenological exploration, as confirmed by the vast literature on the two- and three-Higgs-doublet models. Here, we begin a systematic study of finite non-abelian symmetry groups which can be imposed on the scalar sector of the four-Higgs-doublet model (4HDM) without leading to accidental symmetries. In this work, we derive the full list of such non-abelian groups available in the 4HDM that can be constructed as extensions of cyclic groups by their automorphism groups. This list is remarkably restricted but it contains cases which have not been previously studied. Since the methods we develop may prove useful for other classes of models, we present them in a pedagogical manner.
Simultaneous Approximation via Laplacians on the Unit Ball
Authors: Marriaga Misael E. , Pérez Teresa E. , Recarte Marlon J. 
Published: October 2023

AbstractWe study the orthogonal structure on the unit ball $$\textbf{B}^d$$

B
d

of $$\mathbb {R}^d$$

R

d

with respect to the Sobolev inner products $$\begin{aligned} \left\langle f,g\right\rangle _{\Delta } =\lambda \, \mathscr {L}(f,g) + \int _{\textbf{B}^d}{\Delta [(1-\Vert x\Vert ^2) f(x)] \, \Delta [(1-\Vert x\Vert ^2) g(x)]\,\textrm{d}x}, \end{aligned}$$

f
,
g

Δ

=
λ

L

(
f
,
g
)

+

∫

B
d

Δ
[
(
1

-

‖
x
‖

2

)
f

(
x
)

]

Δ
[
(
1

-

‖
x
‖

2

)
g

(
x
)

]

d
x

,

where $$\mathscr {L}(f,g) = \int _{\textbf{S}^{d-1}}f(\xi )\,g(\xi )\,\textrm{d}\sigma (\xi )$$

L

(
f
,
g
)

=

∫

S

d
-
1

f

(
ξ
)

g

(
ξ
)

d
σ

(
ξ
)

or $$\mathscr {L}(f,g) = f(0) g(0)$$

L
(
f
,
g
)
=
f
(
0
)
g
(
0
)

, $$\lambda >0$$

λ
>
0

, $$\sigma $$
σ
denotes the surface measure on the unit sphere $$\textbf{S}^{d-1}$$

S

d
-
1

, and $$\Delta $$
Δ
is the usual Laplacian operator. Our main contribution consists in the study of orthogonal polynomials associated with $$\langle \cdot , \cdot \rangle _{\Delta }$$

⟨
·
,
·
⟩

Δ

, giving their explicit expression in terms of the classical orthogonal polynomials on the unit ball, and proving that they satisfy a fourth-order partial differential equation, extending the well-known property for ball polynomials, since they satisfy a second-order PDE. We also study the approximation properties of the Fourier sums with respect to these orthogonal polynomials and, in particular, we estimate the error of simultaneous approximation of a function, its partial derivatives, and its Laplacian in the $$L^2(\textbf{B}^d)$$

L
2

(

B
d

)

space.
Silencing circSERPINE2 restrains mesenchymal stem cell senescence via the YBX3/PCNA/p21 axis
Authors: Chen Fenglei , Wang Shan , Zeng Chenying , Tang Su’an , Gu Huimin , Wang Ziming , Li Jinteng , Feng Pei , Zhang Yunhui , Wang Peng , Wu Yanfeng , Shen Huiyong 
Published: October 2023

AbstractIncreasing evidence indicates that circular RNAs (circRNAs) accumulate in aging tissues and nonproliferating cells due to their high stability. However, whether upregulation of circRNA expression mediates stem cell senescence and whether circRNAs can be targeted to alleviate aging-related disorders remain unclear. Here, RNA sequencing analysis of differentially expressed circRNAs in long-term-cultured mesenchymal stem cells (MSCs) revealed that circSERPINE2 expression was significantly increased in late passages. CircSERPINE2 small interfering RNA delayed MSC senescence and rejuvenated MSCs, while circSERPINE2 overexpression had the opposite effect. RNA pulldown followed by mass spectrometry revealed an interaction between circSERPINE2 and YBX3. CircSERPINE2 increased the affinity of YBX3 for ZO-1 through the CCAUC motif, resulting in the sequestration of YBX3 in the cytoplasm, inhibiting the association of YBX3 with the PCNA promoter and eventually affecting p21 ubiquitin-mediated degradation. In addition, our results demonstrated that senescence-related downregulation of EIF4A3 gave rise to circSERPINE2. In vivo, intra-articular injection of si-circSerpine2 restrained native joint-resident MSC senescence and cartilage degeneration in mice with aging-related osteoarthritis. Taken together, our findings provide strong evidence for a regulatory role for the circSERPINE2/YBX3/PCNA/p21 axis in MSC senescence and the therapeutic potential of si-circSERPINE2 in alleviating aging-associated syndromes, such as osteoarthritis.
t-Structures with Grothendieck hearts via functor categories
Authors: Saorín Manuel , Št’ovíček Jan 
Published: October 2023

AbstractWe study when the heart of a t-structure in a triangulated category $$\mathcal {D}$$
D
with coproducts is AB5 or a Grothendieck category. If $$\mathcal {D}$$
D
satisfies Brown representability, a t-structure has an AB5 heart with an injective cogenerator and coproduct-preserving associated homological functor if, and only if, the coaisle has a pure-injective t-cogenerating object. If $$\mathcal {D}$$
D
is standard well generated, such a heart is automatically a Grothendieck category. For compactly generated t-structures (in any ambient triangulated category with coproducts), we prove that the heart is a locally finitely presented Grothendieck category. We use functor categories and the proofs rely on two main ingredients. Firstly, we express the heart of any t-structure in any triangulated category as a Serre quotient of the category of finitely presented additive functors for suitable choices of subcategories of the aisle or the co-aisle that we, respectively, call t-generating or t-cogenerating subcategories. Secondly, we study coproduct-preserving homological functors from $$\mathcal {D}$$
D
to complete AB5 abelian categories with injective cogenerators and classify them, up to a so-called computational equivalence, in terms of pure-injective objects in $$\mathcal {D}$$
D
. This allows us to show that any standard well generated triangulated category $$\mathcal {D}$$
D
possesses a universal such coproduct-preserving homological functor, to develop a purity theory and to prove that pure-injective objects always cogenerate t-structures in such triangulated categories.
Pointwise stabilization of Bresse systems
Authors: Muñoz Rivera Jaime E. , Naso Maria Grazia 
Published: October 2023

AbstractBresse system over the interval (0, L) with pointwise dissipation at $$\xi \in (0,{L})$$

ξ
∈
(
0
,
L
)

is analyzed. The exponential stability of the related semigroup is shown provided the dissipative points are of the form $$\xi \in \mathbb {Q}{L}$$

ξ
∈
Q
L

and $$\xi \ne \frac{n}{2m+1}L$$

ξ
≠

n

2
m
+
1

L

, where $$n,m\in \mathbb {N}$$

n
,
m
∈
N

and n, and $$2m+1$$

2
m
+
1

are co-prime.
A short remark on inviscid limit of the stochastic Navier–Stokes equations
Authors: Chaudhary Abhishek , Vallet Guy 
Published: October 2023

AbstractIn this article, we study the inviscid limit of the stochastic incompressible Navier–Stokes equations in three-dimensional space. We prove that a subsequence of weak martingale solutions of the stochastic incompressible Navier–Stokes equations converges strongly to a weak martingale solution of the stochastic incompressible Euler equations in the periodic domain under the well-accepted hypothesis, namely Kolmogorov hypothesis (K41).
Pandemic, sentiments over COVID-19, and EU convergence
Authors: Anastasiou Athanasios , Apergis Nicholas , Zervoyianni Athina 
Published: October 2023

AbstractThis study examines the convergence/divergence of people's sentiments over Covid-19 in European economies and investigates the role of the support policies that were implemented by governments and central banks. The analysis focuses on 26 EU countries plus the UK, using changes in human mobility to essential places as a proxy for pessimistic/optimistic sentiments. Based on a panel-clustering methodology and multinomial logistic regressions, the results suggest heterogeneous effects of Covid-19 on people’s behavior in Europe, which were not drastically reduced through fiscal- or monetary-policy interventions. Heterogeneous Covid-19 impacts are a matter of concern in the EU context, where harmonization is a primary target. Thus, given the need for harmonization, additional EU-wide support policies are necessary in the post-Covid-19 era in order to effectively address asymmetries across member economies and restore the convergence process.