bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inferring the impacts of climate extreme in the Kabul River Basin
Authors: Khatiwada Kabi Raj , Pradhananga Saurav , Nepal Santosh 
Published: January 2024

AbstractThe increasing temperature and variability in precipitation, in terms of both frequency and intensity, are affecting different sectors in the Himalayan region. This study aims to quantify the future scenario and related extremes in the Kabul River Basin (KRB) of the western Himalaya using high-resolution climate datasets. We selected four representative General Circulation Model (GCM) runs from Representative Concentration Pathway (RCP) 4.5 and 8.5 scenarios, based on future projections, climatic extremes and their abilities to represent the historical climate cycle (1981–2010) of KRB. The seasonal analysis of precipitation shows decreasing pattern during the winter and pre-monsoon seasons and annual mean temperature will increase consistently by 3 to 5 °C in RCP4.5 and 8.5 scenarios. Ten indices were selected to study climatic extremes pertaining to the health, agriculture and water resources sectors. The extremes, like consecutive summer days, warm days and heatwaves, will increase, whereas the frost days, cold nights, cold waves and extreme precipitation days will decrease towards the end of this century. Besides, the extremes are not homogenous in time and space. Based on the results of this study, there is a need for prompt climate actions in order to increase the adaptive capacity against these extreme changes and to build resilient livelihoods in the KRB.
Linking telomere dynamics to evolution, life history and environmental change: perspectives, predictions and problems
Authors: Monaghan Pat 
Published: January 2024

AbstractThis perspectives paper considers the value of studying telomere biology outside of a biomedical context. I provide illustrative examples of the kinds of questions that evolutionary ecologists have addressed in studies of telomere dynamics in non-model species, primarily metazoan animals, and what this can contribute to our understanding of their evolution, life histories and health. I also discuss why the predicted relationships between telomere dynamics and life history traits, based on the detailed cellular studies in humans and model organisms, are not always found in studies in other species.
“Every morning I take two steps to my desk…”: students’ perspectives on distance learning during the COVID-19 pandemic
Authors: Chiodaroli Marco , Freyhult Lisa , Solders Andreas , Tarrío Diego , Günter Katerina Pia 
Published: January 2024

AbstractDuring the COVID-19 pandemic, distance learning became the predominant teaching method at most universities, exposing students and teachers alike to novel and unexpected challenges and learning opportunities. Our study is situated in the context of higher physics education at a large Swedish university and adopts a mixed-methods approach to explore how students perceive shifts to distance learning. Quantitative student survey responses comparing distance learning during the pandemic with previous in-person learning are analyzed with k-means cluster analysis and with a random-intercept multilevel linear model. Combined analyses produce a consistent picture of students who report having experienced the greatest challenges. They are on average younger, report being less autonomous in their learning, and find it harder than peers to ask questions to the instructor. They are also less likely to have access to a place where they can study without interruptions. Variation across courses is small with students being largely subjected to the same set of challenges. Qualitative data from semi-structured focus group interviews and open-ended questions supports these findings, provides a deeper understanding of the struggles, and reveals possibilities for future interventions. Students report an overall collapse of structure in their learning that takes place along multiple dimensions. Our findings highlight a fundamental role played by informal peer-to-peer and student-instructor interactions, and by the exchange of what we refer to as “structural information.” We discuss implications for teachers and institutions regarding the possibility of providing support structures, such as study spaces, as well as fostering student autonomy.
High Public Good Values for Ecosystem Service Attributes of on-farm Quinoa Diversity Conservation in Peru
Authors: Drucker Adam G. , Pradel Willy , Scott Craig , Elmes Sarah , Arpazi Valero Kleny G. , Zander Kerstin K. 
Published: January 2024

AbstractAgrobiodiversity is associated with a range of important but poorly quantified public good ecosystem services, the conservation of which requires public support. With a view to determining the general public’s willingness to pay (WTP) for such conservation, we organised interviews with 491 adult Peruvian residents in three regions a stated preference choice experiment (CE) to elicit the value they place on crop genetic resources conservation, using quinoa cultivation as a case study. Responses revealed strong support for the conservation of quinoa diversity particularly when conservation was framed in terms of conserving national cultural identity or food security. Respondents were willing to make a one-off donation of US$31.79 to an in situ on-farm quinoa crop diversity conservation programme, placing the highest values on programme attributes related to securing bequest/existence and option values, followed closely by stable landscape conservation. WTP was higher when the public was reminded that conservation also contributed to national cultural identify or food security. A conservative aggregation of the WTP estimates to the population of the three regions results in an estimated total WTP for quinoa conservation of US$24.18 m and a benefit-cost ratio of 1.22. Findings demonstrate the significant and frequently ignored social welfare benefits associated with non-market agrobiodiversity-related public good ecosystem services, in this case equivalent to just over a quarter of market production values. Such information can be used to design and prioritise quinoa genetic diversity conservation programmes with an emphasis on such attributes.
Mental Health and Behavioral Interventions for Children and Adolescents with Incarcerated Parents: A Systematic Review
Authors: Merhi Dania , Demou Evangelia , Niedzwiedz Claire 
Published: January 2024

AbstractParental incarceration is a traumatic experience that affects millions of children and adolescents worldwide. This population is at an increased risk of suffering from mental health problems and problematic behaviors that can lead to future delinquency, furthering the inter-generational cycle of criminality. The aim of this systematic review is to evaluate the effectiveness of different types of interventions for the mental health and behavior of children and adolescents with incarcerated parents. The following databases were searched to retrieve relevant studies from 1995 to 2021: PsycINFO, Psychology and Behavioral Sciences Collection, Child Development and Adolescent Studies, SocINDEX, CINAHL, MEDLINE, Embase, and the Web of Science Core Collection. Quality assessment was performed using the Critical Appraisal Skills Programme qualitative checklist and the “Quality Assessment Tool for Quantitative Studies” developed by the Effective Public Health Practice Project. The initial search yielded 2,711 records and 16 studies met the inclusion criteria. The narrative synthesis conducted determined that interventions focusing on improving caregiver outcomes and support, and maternal attachment may be effective in reducing mental health problems and problematic behaviors, however, findings need to be evaluated with regards to the included studies’ quality of evidence since many (n = 7) had a weak rating. Future research should aim to conduct a comparative analysis between the effectiveness of different types of interventions, while focusing on improving the quality of the evidence.
Corporate Responsibility to Respect Human Rights Defenders Under the UNGPs and Steps Towards Mandatory Due Diligence
Authors: Koula Aikaterini-Christina 
Published: January 2024

AbstractBesides state actors, non-state actors and particularly private companies target human rights defenders (HRDs) and violate their rights to intimidate and stop them from challenging their interests. Despite the absence of responsibility of non-state actors in international human rights law, the United Nations Guiding Principles on Business and Human Rights (UNGPs) set out global standards and acknowledge the role of HRDs in the promotion of human rights, urging corporations to work closely with defenders. Considering the effectiveness of the UNGPs, the article explores the potential for protecting HRDs within the framework and concludes that the UNGPs could be utilised to enhance the protection of defenders in relation to business activities. It also suggests that current efforts of implementation would be strengthened by mandatory human rights due diligence laws at the national and regional levels, and emphasises that a clear inclusion of corporate responsibility to respect defenders is required, as it would be beneficial for both sides, defenders and business enterprises.
Cholesterol associated genetic risk score and acute coronary syndrome in Czech males
Authors: Hubacek Jaroslav A. , Adamkova Vera , Lanska Vera , Staněk Vladimir , Mrázková Jolana , Gebauerová Marie , Kettner Jiri , Kautzner Josef , Pitha Jan 
Published: January 2024

Abstract

Background
Despite a general decline in mean levels across populations, LDL-cholesterol levels remain a major risk factor for acute coronary syndrome (ACS). The APOB, LDL-R, CILP, and SORT-1 genes have been shown to contain variants that have significant effects on plasma cholesterol levels.

Methods and results
We examined polymorphisms within these genes in 1191 controls and 929 patients with ACS. Only rs646776 within SORT-1 was significantly associated with a risk of ACS (P < 0.05, AA vs. + G comparison; OR 1.21; 95% CI 1.01–1.45). With regard to genetic risk score (GRS), the presence of at least 7 alleles associated with elevated cholesterol levels was connected with increased risk (P < 0.01) of ACS (OR 1.26; 95% CI 1.06–1.52). Neither total mortality nor CVD mortality in ACS subjects (follow up—9.84 ± 3.82 years) was associated with the SNPs analysed or cholesterol-associated GRS.

Conclusions
We conclude that, based on only a few potent SNPs known to affect plasma cholesterol, GRS has the potential to predict ACS risk, but not ACS associated mortality.
A trilemma for the lexical utility model of the precautionary principle
Authors: Stefánsson H. Orri 
Published: January 2024

AbstractBartha and DesRoches (Synthese 199(3–4):8701–8740, 2021) and Steel and Bartha (Risk Analysis 43(2):260–268, 2023) argue that we should understand the precautionary principle as the injunction to maximise lexical utilities. They show that the lexical utility model has important pragmatic advantages. Moreover, the model has the theoretical advantage of satisfying all axioms of expected utility theory except continuity. In this paper I raise a trilemma for any attempt at modelling the precautionary principle with lexical utilities: it permits choice cycles or leads to paralysis or implies that the smallest value difference that is possible in a context has extreme axiological implications.
Monadic panpsychism
Authors: Kadić Nino 
Published: January 2024

AbstractOne of the main obstacles for panpsychism, the view that consciousness is fundamental and ubiquitous, is the difficulty of explaining how simple subjects could combine to form complex subjects. Known as the subject combination problem, it poses a possibly insurmountable challenge to the view. In this paper, I will assume that this challenge cannot be overcome and instead present a version of panpsychism that completely avoids talk of combination. Inspired by Gottfried Wilhelm Leibniz’s metaphysics of monads, I will focus on a relational explanation of how simple subjects could constitute complex experiences, without them having to combine in virtue of their subjectivity. I call this view monadic panpsychism. Additionally, my proposal will not rely on emergence and so it will circumvent problems commonly faced by emergentist accounts. As I will argue, monadic panpsychism is preferable to combinatory and emergentist panpsychism because it faces a significantly less worrisome set of objections. Apart from being unaffected by the seemingly insuperable issue of subject combination, I will demonstrate that monadic panpsychism also has tools to address other kinds of the combination problem. That alone justifies the need for a new formulation of panpsychism, one which faces unique difficulties but also offers unique solutions.
The social contract for science and the value-free ideal
Authors: Douglas Heather , Branch T. Y. 
Published: January 2024

AbstractWhile the Value-Free Ideal (VFI) had many precursors, it became a solidified bulwark of normative claims about scientific reasoning and practice in the mid-twentieth century. Since then, it has played a central role in the philosophy of science, first as a basic presupposition of how science should work, then as a target for critique, and now as a target for replacement. In this paper, we will argue that a narrow focus on the VFI is misguided, because the VFI coalesced in the midst of other important shifts in the relationship between science and society. In particular, the mid-twentieth century saw the acceptance of the “social contract for science,” a tacit agreement between scientists and government officials, and more broadly between science and society. It was built around three core concepts: a distinction between basic and applied science, a conception of scientific freedom that limited social responsibility for scientists, and a justification for public funding of basic science in the form of the linear model. Within the conceptual framework of the social contract for science, it is clearer both (1) why the VFI was adopted, (2) why it is difficult to replace the VFI within the old social contract, and (3) how we need to revise the social contract for science in order to replace the VFI.
Parasaturnius maurepasi n. gen. et n. comb. (Digena: Bunocotylidae) from the stomach of the silver mullet, Mugil curema (Perciformes: Mugilidae) in coastal lagoons of northern Yucatán, Mexico
Authors: Andrade-Gómez Leopoldo , Pérez-Ponce de León Gerardo 
Published: January 2024

AbstractBunocotylid trematodes represent a group of 149 species with a rather complex taxonomic history. The current concept of the subfamily only includes three genera, Bunocotyle, Saturnius, and Robinia. Specimens of a bunocotylid were collected from the silver mullet, M. curema, from a coastal lagoon of Yucatán and identified as belonging to Saturnius. Further detailed morphological study revealed they corresponded to S. maurepasi, a species previously reported from the stripped mullet, Mugil cephalus in Mississippi, USA. Specimens were sequenced for the LSU of nuclear ribosomal RNA gene (28S) to test their phylogenetic position. We discovered that they do not belong in Saturnius since they nest as an independent lineage which is the sister taxa of a clade formed by Robinia, and Saturnius + Bunocotyle; additionally, the new genus exhibits high genetic divergence (10-12%) with respect to species allocated in the other bunocotylid genera. The species S. maurepasi was then transferred to the new genus as Parasaturnius maurepasin. gen., n. comb. that was created to accommodate it, and was redescribed based on newly sampled specimens.
Flow Characterization in a Partially Liquefied Vitreous Humor
Authors: Khoobyar Anahid , Penkova Anita , Humayun Mark S. , Irimia Andrei , Sadhal Satwindar Singh 
Published: January 2024

AbstractThe purpose of this study is to systematically examine the basic fluid dynamics associated with a fully liquid region within a porous material. This work has come about as a result of our investigation on the ocular fluid dynamics and transport process in a partially liquefied vitreous humor. The liquid is modeled as a sphere with Stokes flow while the surrounding infinite porous region is described by Brinkman flow. The development here provides basic three-dimensional axisymmetric results on flow characterization and also serves to evaluate the limits of validity of Darcy flow analysis for the same geometry. In the Darcy flow model, the liquid region is also treated as a porous region with a much higher permeability. Therefore, both liquid and porous regions are modeled by Darcy’s law. Besides the analytical results from Brinkman–Stokes model, the simpler case of Darcy–Darcy flow for the same geometry has been provided. The results of both cases are compared and the differences between the two sets of results provide the range of validity of our computational model (Khoobyar et al. in J Heat Transf 144:031208, 2022). Some interesting fluid-dynamical aspects of the system are observed through the analysis. For the Darcy–Darcy system, the liquid region velocity is uniform throughout, as expected for potential flow. With the Brinkman–Stokes model, the liquid region has a paraboloidal profile with the maximum possible peak value of six times the far-field velocity in the porous medium. With the liquid region having a lower resistance, the flow tends to converge there for both models as it seeks the path of least resistance. As for the validation of the Darcy–Darcy model, it is a good approximation as far as the exterior flow is concerned. However, the liquid region flow profiles for the two models are different as noted. The current Brinkman–Stokes model has led to explicit analytical solutions for the flow field for both regions. This has permitted an asymptotic analysis giving deeper insight into the flow characterization.
Comparison of photoinduced and electrochemically induced degradation of venlafaxine
Authors: Voigt Melanie , Dluziak Jean-Michel , Wellen Nils , Langerbein Victoria , Jaeger Martin 
Published: January 2024

AbstractThe European Union requires environmental monitoring of the antidepressant drug venlafaxine. Advanced oxidation processes provide a remedy against the spread of micropollutants. In this study, the photoinduced and electrochemical decompositions of venlafaxine were investigated in terms of mechanism and efficacy using high-performance liquid chromatography coupled to high-resolution multifragmentation mass spectrometry. Kinetic analysis, structure elucidation, matrix variation, and radical scavenging indicated the dominance of a hydroxyl-mediated indirect mechanism during photodegradation and hydroxyl and direct electrochemical oxidation for electrochemical degradation. Oxidants, sulfate, and chloride ions acted as accelerants, which reduced venlafaxine half-lives from 62 to 25 min. Humic acid decelerated degradation during ultra-violet irradiation up to 50%, but accelerated during electrochemical oxidation up to 56%. In silico quantitative structure activity relationship analysis predicted decreased environmental hazard after advanced oxidation process treatment. In general, photoirradiation proved more efficient due to faster decomposition and slightly less toxic transformation products. Yet, matrix effects would have to be carefully evaluated when potential applications as a fourth purification stage were to be considered.
Robot-assisted language assessment: development and evaluation of feasibility and usability
Authors: Seok Sukyung , Choi Sujin , Kim Kimun , Choi Jongsuk , Sung Jee Eun , Lim Yoonseob 
Published: January 2024

AbstractMany studies have shown that robots can provide medical help to patients, such as supporting physical movements, managing mood, or simulating cognitive function. However, robotic cognitive/language assessment, which is vital for mental health care, has not been fully explored and is limited to only a few types of assessment. The aim of this study is to present and evaluate a social robot equipped with a web-based language assessment for sentence comprehension test (SCT) with a dialogue system involving yes/no questions. A total of 50 participants took the test with 36 items conducted by a robot (robot-SCT), while a total of 55 participants took the same test but conducted by a human examiner (human-SCT). Comparative analyses were performed to evaluate the validity of the robot-SCT in terms of test scores and time-related measures. Usability was evaluated through the system usability score and interview feedback. With regard to the validity of the robot-SCT, the test scores indicated no significant differences between the robot-SCT and human-SCT. In addition, conditional differences in reaction time for the test items were observed, similar to the previous paper-and-pencil researches. The high system usability scores (i.e., mean = 78.5, SD = 11) demonstrated the high usability of the robot-SCT. This study demonstrates the validity and usability of robotic language assessment among normal adults. However, further evaluation is required for people with dementia or mild cognitive impairment.
Healthcare Utilization Differences Among Primary Care Patients Using Telemedicine in the Veterans Health Administration: a Retrospective Cohort Study
Authors: O’Shea Amy M. J. , Mulligan Kailey , Carlson Paige , Haraldsson Bjarni , Augustine Matthew R. , Kaboli Peter J. , Shimada Stephanie L. 
Published: January 2024

Abstract
Background
The COVID-19 pandemic encouraged telemedicine expansion. Research regarding follow-up healthcare utilization and primary care (PC) telemedicine is lacking.

Objective
To evaluate whether healthcare utilization differed across PC populations using telemedicine.

Design
Retrospective observational cohort study using administrative data from veterans with minimally one PC visit before the COVID-19 pandemic (March 1, 2019–February 28, 2020) and after in-person restrictions were lifted (October 1, 2020–September 30, 2021).

Participants
All veterans receiving VHA PC services during study period.

Main Measures
Veterans’ exposure to telemedicine was categorized as (1) in-person only, (2) telephone telemedicine (≥ 1 telephone visit with or without in-person visits), or (3) video telemedicine (≥ 1 video visit with or without telephone and/or in-person visits). Healthcare utilization 7 days after index PC visit were compared. Generalized estimating equations estimated odds ratios for telephone or video telemedicine versus in-person only use adjusted for patient characteristics (e.g., age, gender, race, residential rurality, ethnicity), area deprivation index, comorbidity risk, and intermediate PC visits within the follow-up window.

Key Results
Over the 2-year study, 3.4 million veterans had 12.9 million PC visits, where 1.7 million (50.7%), 1.0 million (30.3%), and 649,936 (19.0%) veterans were categorized as in-person only, telephone telemedicine, or video telemedicine. Compared to in-person only users, video telemedicine users experienced higher rates per 1000 patients of emergent care (15.1 vs 11.2; p < 0.001) and inpatient admissions (4.2 vs 3.3; p < 0.001). In adjusted analyses, video versus in-person only users experienced greater odds of emergent care (OR [95% CI]:1.18 [1.16, 1.19]) inpatient (OR [95% CI]: 1.29 [1.25, 1.32]), and ambulatory care sensitive condition admission (OR [95% CI]: 1.30 [1.27, 1.34]).

Conclusions
Telemedicine potentially in combination with in-person care was associated with higher follow-up healthcare utilization rates compared to in-person only PC. Factors contributing to utilization differences between groups need further evaluation.