bluuebunny/crossref_metadata_2025_split huggingface dataset:
APLICACIÓN DEL DERECHO DE LA UNIÓN EUROPEA POR EL TRIBUNAL DE JUSTICIA DE LA UNIÓN EUROPEA PARA RESOLVER LA CUESTIÓN PREJUDICIAL SOBRE LA INTERPRETACIÓN DEL ARTÍCULO 7, APARTADO 2, PRIMER GUIÓN, DE LA DIRECTIVA 86/653/ CEE DEL CONSEJO, DE 18 DE DICIEMBRE DE 1986
Authors: Morales Villanueva Paloma 
Published: November 2023

Litigio principal versa sobre el derecho a la comisión debida que reclama el Agente comercial, Paul Chevassus-Marche, parte demandante y recurrente en primera instancia, apelación y casación, al Principal o Empresario, Sociedad Groupe Danone, y sus filiales, Societé Kro beer brands SA (BKSA) y Societé Évian eaux minérales d´Evian SA (SAEME), todas ellas conjuntamente, como parte demandada y recurrida, tras la resolución del Contrato de Agencia Comercial internacional, reclamando el Agente las comisiones relativas a adquisiciones efectuadas por dos sociedades que pertenecían al sector geográfico coincidente con el pactado con el Principal o Empresario, sin el control del Empresario, es decir de Groupe Danone o sus filiales y sin intervención del Agente en las mismas y el consiguiente planteamiento de cuestión prejudicial sobre la interpretación del artículo 7, apartado 2, primer guión de la Directiva 86/653/CEEE del Consejo, de 18 de diciembre de 1986, relativa a la coordinación de los derechos de los Estados miembros en lo referente a los agentes comerciales independientes, sobre el derecho a la comisión.APLICACIÓN DEL DERECHO DE LA UNIÓN EUROPEA POR EL TRIBUNAL DE JUSTICIA DE LA UNIÓN EUROPEA PARA RESOLVER LA CUESTIÓN PREJUDICIAL SOBRE LA INTERPRETACIÓN DEL ARTÍCULO 7, APARTADO 2, PRIMER GUIÓN, DE LA DIRECTIVA 86/653/ CEE DEL CONSEJO, DE 18 DE DICIEMBRE DE 1986
Drill-In Fluid Optimization for Formation Damage Control Considering Salt Dissolution in Saline-Lacustrine Reservoirs
Authors: Tan Qigui , Yang Bin , You Lijun , Kang Yili , Peng Haoping , Song Fuquan , Lin Chong 
Published: November 2023

Summary
Salt dissolution induced by drill-in fluid loss is a frequent occurrence in saline-lacustrine reservoirs, which can potentially result in serious formation damage. In light of this, an experimental study was conducted to investigate the salt mineral dissolution and dynamic damage in the rock samples collected from a saline-lacustrine carbonate reservoir and the response of pore-fracture structures using the in-situ drill-in fluids. The study further involved analyzing the formation-damage-control (FDC) ability of the in-situ drill-in fluids. The results indicated that although salt dissolution significantly increased the pore size of the tight matrix and the width of natural fractures, improving the conductivity of seepage channels, the increase in pore-fracture size may have greatly aggravated the drill-in fluid loss during the process. The continuous serious filtrate loss, lower pressure-bearing capacity of the plugging zone, and lower permeability recovery rate (PRR) of rock indicated poor FDC performance of in-situ brine drilling fluids for the salt-dissolved core samples. The FDC performance of drill-in fluids for saline-lacustrine carbonate reservoirs was optimized based on the response of reservoir pore-fracture structure to salt dissolution and the theory of slightly underbalanced activity. The experimental results showed that the optimized drill-in fluids had better FDC ability, with an average PRR increase of 14.04%. Field application indicated that the optimized drill-in fluids reduced the drill-in fluid loss by 76.48%, shortened the drilling cycle by 45.20%, and increased the initial production capacity per well by 7.70%. This study can provide insightful guidance to optimize the FDC performance of drill-in fluids for saline-lacustrine hydrocarbon reservoirs during drilling.
Does carbon trading affect the investment efficiency？——DEA test method based on enterprise-caliber
Authors: Liu Biqian , Zhou Chang 
Published: November 2023

Abstract
In order to tackle the severe environmental problems associated with climate warming, countries worldwide have shifted their focus on micro-enterprises. They have effectively guided enterprises to participate in carbon emission projects by establishing several environmental regulations policies that internalize environmental costs. This process will also impact the business activities, innovation activities, and investment decisions of micro-enterprises. In this context, considering the clean development mechanism (CDM) project carried out by China in cooperation with developed countries and China's domestic PPP projects related to climate change mitigation as the research background, this study selects A-share listed companies from 2003 to 2017 as the research sample, constructs enterprise investment efficiency with Data envelopment analysis (DEA) model, and uses two-way fixed multi-period DID model and fixed year and industry OLS model to test the impact of carbon emission projects on the investment efficiency of industry and individual enterprises. The empirical results show that whether from the industry or individual level, carbon emission projects have significantly promoted investment efficiency. The participation of enterprises in carbon trading projects can improve their investment efficiency by increasing R&D (research and development) investment, alleviating financing constraints, and improving risk-taking levels. Further research shows that the investment efficiency of state-owned enterprises, enterprises with a high proportion of institutional investors, and enterprises in highly active carbon market areas is more significantly affected by carbon emission projects.
A Descriptive Study on Patient Satisfaction with Waiting Time in Emergency Departments: Insights from Hospitals in the Northern Emirates
Authors: Mosleh Sultan , Hamoud Aisha R , Saeed Aisha A , Alnaqbi Hessa M , Alhouti Rayan S , Alshehhi Shamma S 
Published: November 2023

Abstract
Background: Long waiting times in emergency departments (EDs) are a major challenge for healthcare systems, especially during the COVID-19 pandemic.
Purpose: identify factors that contribute to low satisfaction levels and long waiting times in EDs in the United Arab Emirates (UAE).
Methods: A quantitative cross-sectional study was conducted, with 394 patients participating.
Results: The overall satisfaction rate was 6.82, with the highest satisfaction with medication (78.6%), and the lowest was related to waiting times (36.7%). There was a negative association between waiting time and patient satisfaction. The four most common barriers to long waiting times were computer systems (46%), crowded waiting lounges (42.7%), understaffing (38.1%), and an inadequate number of examination/consultation rooms (37.3%).
Conclusion: Patient satisfaction is significantly impacted by waiting times in EDs. To improve patient satisfaction, hospital management should address the barriers to long waiting times that were identified in this study.
Climate Change Impact on the Trigger of Natural Disasters Over South-Eastern Himalayas Foothill Region of Myanmar: Extreme Rainfall Analysis
Authors: oo KYAW Than , Haishan CHEN , JONAH Kazora 
Published: November 2023

Abstract
The study examines the characteristics and variability of monsoon rainfall in Myanmar, focusing on the relationship between heavy rainfall, floods, and earthquakes, which impact agriculture, hydrology, and the environment. Generally, heavy rainfall can cause flooding, economic losses, and water table changes. Northern Myanmar floods occur mainly during the monsoon season from June to October and can be classified into widespread floods along major rivers like Ayeyarwady, Thanlwin, Chindwin, and Sittoung, and flash floods in small streams and rivers. Climate change is expected to increase the frequency and intensity of extreme weather events, including heavy rainfall, which can trigger floods or landslides, which also can in turn cause earthquakes. Heavy rainfall over northern Myanmar and the Sagaing faults, which are the main triggers of earthquakes, has been the subject of several studies. The study uses the Copernicus 5 database of Global Climate Model (GCM) simulations with two scenarios analysis on Climate Change Detection and Indices (ETCCDI) to study changes in climatic extremes. Results show high intensity in the northern region and monsoon core regions, while the central region shows less intensity. The study also uses intensity-duration-frequency (IDF) curves to analyze the relationship between rainfall duration, intensity, and return time in major risk zones. The study finds that as short duration lengthens with rainfall intensity increases for future rainfall patterns. This information is expected to be convenient for local authorities and flood protection projects in rural and urban basins.
Apparent Non-Suppression of Chaos in Spatiotemporal Chaotic Systems under Spatial and Temporal Variation of Parameters
Authors: Teli Bishnu Gupta 
Published: November 2023

Abstract
Coupled Map Lattice systems have been extensively studied in the past. The behavior of such systems under various mechanisms for the suppression of chaos has been investigated. The suppression of chaos is investigated here for both spatial as well as temporal variations of parameters. For this, the well-known Logistic map is used as the dynamical system. The method of homogeneous pinning is used as the chaos suppression mechanism. It is found that with pinning conditions, the STC when (i) control parameter r having only spatial variation together with coupling parameter ϵ having either only temporal temporal variation or spatial as well as temporal variation at the same time, (ii) r having temporal variation with every possible variation in ϵ and (iii) r having both spatial as well as temporal variation at the same time with every possible variation in ϵ, appears to have narrow range of values with non-suppression of chaos. However, upon close examination, it is found that the system is not chaotic at all.
Lightweight and Anonymous Mutual Authentication and Key Agreement Scheme for WBAN
Authors: Marandi Saba , Moazami Farokhlagha , Malekinezhad Amir 
Published: November 2023

Abstract

In the medical field, a wearable body area network is a wireless network in which wearable sensors are implemented in or on patients' bodies to gather their sensitive health information and send it to the medical servers accordingly. These multi-functional sensors provide all users with optimized and convenient services, such as homecare monitoring people’s health conditions. On the other hand, the mobility and insecure communication channels pose a vital threat from unauthorized entities to the information transferred in this network and endanger users' privacy. Therefore, numerous authentication and key agreement schemes have been suggested by researchers to solve this issue. Furthermore, the wearable body area network consists of resource-constrained devices. Thus, lightweight protocols are required to guarantee the authenticity, confidentiality, and integrity of the information. Recently, Ankur Gupta and his colleagues proposed a mutual authentication and key agreement protocol and proved its security against well-known attacks. However, after in-depth analysis, we discovered that their proposed protocol is vulnerable to the sensor node impersonation attack, and sensor node capture attack. In this paper, we propose a new lightweight mutual authentication and key agreement scheme in WBAN based on basic symmetric cryptosystems (Exclusive OR and Hash functions) to overcome the security weaknesses in Gupta's protocol and provide indispensable security for communicating data. Unlike the Gupta’s protocol, our proposed scheme is safe in CK-adversary threat model. The security of the presented scheme is evaluated using BAN-Logic, the AVISPA tool, and Real or Random (ROR) model. Overall, the performance comparison of the proposed protocol with the existing related protocols depicts that our new scheme is more efficient than others in terms of communication and computational complexities.
Effect of air pollutants on the processes of fertilization and embryo formation
Authors: Jiang Nan , Huang Qiongxiao 
Published: November 2023

Abstract
Fertilization and embryo cultures are at risk of direct exposure of germ cells to air pollutants in assisted reproductive technology. The degree of exposure of germ cells to the pollutants is different in vitro fertilization methods, conventional in vitro fertilization (c-IVF), and intracytoplasmic sperm injection (ICSI) cycles. However, there are conflicting conclusions about the effect of air pollutants on in vitro cultures. A retrospective analysis of fertilization and embryo cultures of 2689 c-IVF and 1133 ICSI cycles that underwent assisted reproductive treatment for the first time was performed. Weighted binary logistic regression models were used to investigate the correlation between air pollutant exposure and fertilization, cleavage, and embryo development. We found that D− 1-NO2 (adjusted odds ratios (aOR): 0.996; 95% CI: 0.992–1.000) was negatively correlated with normal fertilization, whereas D− 1-PM2.5 (aOR: 0.989; 95% CI: 0.982–0.995) and D1-O3 (aOR: 0.998; 95% CI: 0.997–1.000) were negatively correlated with high-quality embryo formation, D− 1-CO (aOR: 1.631; 95% CI: 1.152–2.311) and D− 1-O3 (aOR: 1.002; 95% CI: 1.001–1.004) were positively correlated with high-quality embryo formation. In c-IVF cycles, D0-SO2 (aOR: 0.974; 95% CI: 0.953–0.995) was negatively correlated with normal fertilization, D− 1-PM2.5 (aOR: 0.986; 95% CI: 0.978–0.993) was negatively correlated with high-quality embryos formation, and D− 1-CO (aOR: 1.498; 95% CI: 1.002–2.240; p = 0.049) was positively correlated with high-quality embryos formation. In ICSI cycles, D− 1-NO2 (aOR: 0.991; 95%CI: 0.983–0.999) was negatively correlated with normal fertilization, whereas D− 1-CO (OR: 2.161; 95%CI: 1.068–4.373) and D− 1-O3 (OR: 1.004; 95%CI: 1.001–1.007) were positively correlated with high-quality embryos formation. We conclude that air pollutants affect the processes of fertilization and embryo development in vitro; however, the types and interference stages of air pollutants that affect germ cell cultures in vitro are different in c-IVF and ICSI.
Nature-derived five-star general fighting postoperative abdominal adhesion
Authors: Jin Lin , Pan Xiaolin , Ren Congling , Chen Xing , Liu Xiaoli , Yang Zhe , Wang Taoxia , Li Guiying , Zhang Xingcai 
Published: November 2023

Abstract
Postoperative adhesion of abdominal is one of major surgical complications, mainly due to inflammation in the wound tissue causing adhesion between the wound tissue and the tissue. These adhesions not only cause the loss of functional parts, but also seriously affect the postoperative rehabilitation. Recently, researchers have developed various types of hydrogels as barriers to prevent adhesion through physical and mechanical isolation. However, the swelling of hydrogel may lead to the new inflammation and generate excessive reactive oxygen species (ROS), inducing the tissue adhesion again. Herein, we designed a Nature-derived five-star general fighting postoperative abdominal adhesion, which possesses a five-star function of anti-swelling, ROS clearance, inflammation inhibition, anti-bacterial and anti-adhesion. Thus, the swelling rate of the prepared nanofiber hydrogel system is confined to 1.21 times, the antibacterial efficiency is 96%, and the adhesion inhibition efficiency is 99%. Combined with its excellent performance, we believe that the prepared anti-swelling, ROS scavenging and antibacterial composite hydrogel system will provide a new strategy for clinical postoperative adhesion inhibition.
Impaired bone morphogenetic protein (BMP) signaling pathways disrupt decidualization in endometriosis
Authors: Monsivais Diana , Liao Zian , Tang Suni , Jiang Peixin , Geng Ting , Cope Dominique , Dunn Timothy , Guner Joie , Radilla Linda Alpuing , Guan Xiaoming 
Published: November 2023

Abstract
Endometriosis is linked to increased infertility and pregnancy complications due to defective endometrial decidualization. We hypothesized that identification of altered signaling pathways during decidualization could identify the underlying cause of infertility and pregnancy complications. Our study reveals that transforming growth factor β (TGFβ) pathways are impaired in the endometrium of individuals with endometriosis, leading to defective decidualization. Through detailed transcriptomic analyses, we discovered abnormalities in TGFβ signaling pathways and key regulators, such as SMAD4, in the endometrium of affected individuals. We also observed compromised activity of bone morphogenetic proteins (BMP), a subset of the TGFβ family, that control endometrial receptivity. Using 3-dimensional models of endometrial stromal and epithelial assembloids, we showed that exogenous BMP2 improved decidual marker expression in individuals with endometriosis. Our findings unveil a previously unidentified dysfunction in BMP/SMAD signaling in the endometrium of individuals with endometriosis, explaining decidualization defects and subsequent pregnancy complications in these individuals.
Risk factors for incident fragility fractures in patients with rheumatoid arthritis: An cohort study based on a nation-wide prospective registry
Authors: Hou Ruihong , Jin Shangyi , Duan Xinwang , Fang Yongfei , Luo Hui , Wu Lijun , Li Hongbin , Wang Yongfu , Jiang Nan , Wang Qian , Tian Xinping , Zhang Liyun , Li Mengtao , Zeng Xiaofeng 
Published: November 2023

Abstract

Objective
To identify the risk factors associated with incident fragility fractures in Chinese patients with rheumatoid arthritis (RA).
Methods
This study was based on the Chinese Registry of rhEumatoiD arthrITis (CREDIT), a nation-wide prospective registry. For each patient with incident fragility fracture, 20 control patients with matched follow-up duration (with < 1 month difference) were randomly selected for analysis using multivariable logistic regression analysis. Results are shown as odds ratio (OR) and 95% confidence interval (CI).
Results
A total of 11564 patients were screened. Incident fragility fracture occurred in 32 patients (27 women) patients during the median follow-up of 24.5(10.3, 31.8)months. In comparison to the control patients (n = 642; 534 women), patients who developed fragility fractures had older age, higher rate of menopause, longer disease duration, higher rate of morning stiffness, higher number of swollen joints and higher DAS28 CRP at the baseline. The cases also had lower use rate for glucocorticoid, csDMARDs, and calcium-vitamin D supplementation. In multivariable logistic regression, incident fragility fracture was associated with older age (OR: 1.006 per year, 95%CI: 1.001, 1.011), longer disease duration (OR: 1.006 per year, 95%CI: 1.001, 1.011), menopause (OR: 28.411, 95%CI: 3.154, 255.935), and no calcium-vitamin D supplementation (OR: 4.505, 95%CI: 1.414, 14.289).
Conclusion
Risk factors for incident fragility fracture in RA patients included older age, longer disease duration, menopause and no calcium-vitamin D supplementation.
Estimands for clinical endpoints in Tuberculosis treatment randomized controlled trials: a retrospective application in a completed trial
Authors: Weir Isabelle R , Dufault Suzanne M , Phillips Patrick PJ 
Published: November 2023

Abstract
Background:
Randomized trials for the treatment of tuberculosis (TB) rely on a composite primary outcome to capture unfavorable treatment responses. However, variability between trials in the outcome definition and estimation methods complicates across-trial comparisons and hinders the advancement of treatment guidelines. The International Council for Harmonization (ICH) provides international regulatory standards for clinical trials. The estimand framework outlined in the recent ICH E9(R1) addendum offers a timely opportunity for randomized trials of TB treatment to adopt broadly standardized outcome definitions and analytic approaches. We previously proposed and defined four estimands for use in this context. Our objective was to evaluate how the use of these estimands and choice of estimation method impacts results and interpretation of a large phase III TB trial.
Methods:
We reanalyzed participant level data from the REMoxTB trial. We applied four estimands and various methods of estimation to assess non-inferiority of both novel 4-month treatment regimens against standard of care.
Results:
With each of the four estimands we reached the same conclusion as the original trial analysis; that the novel regimens were not non-inferior to standard of care. Each estimand and method of estimation gave similar estimates of the treatment effect with fluctuations in variance and differences driven by the methods applied for handling intercurrent events.
Conclusions:
Our application of estimands defined by the ICH E9(R1) addendum offers a formalized framework for addressing the primary TB treatment trial objective and can promote uniformity in future trials by limiting heterogeneity in trial outcome definitions. We demonstrated the utility of our proposal using data from the REMoxTB randomized trial. We outlined methods for estimating each estimand and found consistent conclusions across estimands. We recommend future late-phase TB treatment trials to implement some or all of our estimands to promote rigorous outcome definitions and reduce variability between trials.
Trial registration: NCT00864383
Validating the Delone and Mclean’s Model in a Developing Country's Infectious Disease Pandemic Context
Authors: Ikenyei Uche , Haggerty Nicole 
Published: November 2023

Abstract

Purpose: This study aimed at validating the updated DeLone and McLean’s information systems success model (D&MISS) in a developing country’s infectious disease pandemic preparedness and response context. The findings are relevant to inform policies and actions for enhancing the Health Information System’s (HIS) performance in developing countries specifically to improve their future pandemic readiness and response. The study sought to respond to a key research question; to what extent can the D&MISS model provide evidence to improve the HIS’s infectious disease pandemic readiness and response in developing countries?
Method: A cross-sectional study design that involved a multistage sampling approach to select eligible respondents was applied. Conducted in Nigeria and Liberia, 576 primary healthcare workers, out of the planned 600, participated representing a response rate of 96%. The D&MISS model served as the theoretical underpinning for this study and nine hypothesized relationships were stated prior to the study based on the interconnectedness of the model’s six dimensions.
Results: Eight of the nine hypothesized relationships were supported, except for the relationship between Information Quality and Use. The relationships between System Quality and Use and between User Satisfaction and Net Benefit had the highest beta coefficient which was statistically significant at p<0.05.
Conclusion and Relevance: While the D&MISS model continues to remain valuable in information systems (IS) and HIS research, its enhancement with context specific dimensions will improve its ability to determine context specific gaps peculiar to developing countries. The results of which will improve their HIS’s pandemic preparedness and response.