Dyslipidemia in the Russian Federation: population data, associations with risk factors
Authors: Drapkina O. M. , Imaeva A. E. , Kutsenko V. A. , Kapustina A. V. , Balanova Yu. A. , Maksimov S. A. , Muromtseva G. A. , Kotova M. B. , Karamnova N. S. , Evstifeeva S. E. , Litinskaya O. A. , Pokrovskaya M. S. , Imaeva N. A. , Filichkina E. M. , Ivlev O. E. , Svinin G. E. , Gomanova L. I. , Doludin Yu. V. , Efimova I. A. , Borisova A. L. , Nazarov B. M. , Yarovaya E. B. , Repkina T. V. , Gonoshilova T. O. , Kudryavtsev A. V. , Belova N. I. , Shagrov L. L. , Samotrueva M. A. , Yasenyavskaya A. L. , Chernysheva E. N. , Glukhovskaya S. V. , Levina I. A. , Shirshova E. A. , Dorzhieva E. B. , Urbanova E. Z. , Borovkova N. Yu. , Kurashin V. K. , Tokareva A. S. , Ragino Yu. I. , Simonova G. I. , Shramko V. S. , Nikulin V. N. , Aslyamov O. R. , Khokhlova G. V. , Solovyova A. V. , Rodionov A. A. , Kryachkova O. V. , Shamurova Yu. Yu. , Tantsyreva I. V. , Baryshnikova I. N. , Ataev M. G. , Radjabov M. O. , Isakhanova M. M. , Umetov M. A. , Elgarova L. V. , Khakuasheva I. A. , Yamashkina E. I. , Esina M. V. , Kunyaeva T. A. , Nikitina A. M. , Savvina N. V. , Spiridonova Yu. E. , Naumova E. A. , Keskinov A. A. , Yudin V. S. , Yudin S. M. , Kontsevaya A. V. , Shalnova S. A. 
Published: February 2024

Aim. To study the prevalence of dyslipidemias and their association with various risk factors in the Russian population of men and women aged 35-74 years in 2020-2022.Material and methods. This work was carried out as part of the Epidemiology of Cardiovascular Diseases and their Risk Factors in Regions of Russian Federation-3 (ESSE-RF3) study. The sample included 28731 men and women aged 35-74 years living in 15 Russian regions. Hypercholesterolemia (HC) was diagnosed with total cholesterol (TC) ≥5,0 mmol/l, while elevated low-density lipoprotein cholesterol (LDL-C) was considered ≥3,0 mmol/l, hypertriglyceridemia — with triglyceride levels ≥1,7 mmol/l, reduced high-density lipoprotein cholesterol (HDL-C) <1,0 mmol/l in men and <1,2 mmol/l in women. Associations were assessed using logistic regression after adjustment for socio-demographic characteristics, drinking status, presence of hypertension (HTN) and stroke.Results. The prevalence of hypertriglyceridemia in the Russian Federation in 2020-2022 was 58,8%, hypertriglyceridemia — 32,2%. The incidence of lipid-lowering therapy increased with age from 1% in the group of 35-44 years to 16% in the group of 65-74 years. On average, only 7,6% of study participants received lipid-lowering therapy. Significant associations of HC with HTN, obesity and alcohol abuse were identified. Similar results were obtained for elevated LDL-C levels, with the exception of alcohol abuse. In turn, a reduced HDL-C level was significantly associated with the lack of higher education, marriage, physical activity, smoking and the presence of diseases.Conclusion. The prevalence of lipid disorders in the Russian Federation in 2020-2022 remained at a high level. These disorders occurred more often in women, and they were better informed about their cholesterol levels and more often received lipid-lowering therapy. HTN, obesity, and some behavioral and social risk factors were associated with dyslipidemia.