bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coupled Ferroelectric‐Photonic Memory in a Retinomorphic Hardware for In‐Sensor Computing
Authors: Duong Ngoc Thanh , Shi Yufei , Li Sifan , Chien Yu‐Chieh , Xiang Heng , Zheng Haofei , Li Peiyang , Li Lingqi , Wu Yangwu , Ang Kah‐Wee 
Published: January 2024

AbstractThe development of all‐in‐one devices for artificial visual systems offers an attractive solution in terms of energy efficiency and real‐time processing speed. In recent years, the proliferation of smart sensors in the growth of Internet‐of‐Things (IoT) has led to the increasing importance of in‐sensor computing technology, which places computational power at the edge of the data‐flow architecture. In this study, a prototype visual sensor inspired by the human retina is proposed, which integrates ferroelectricity and photosensitivity in two‐dimensional (2D) α‐In2Se3 material. This device mimics the functions of photoreceptors and amacrine cells in the retina, performing optical reception and memory computation functions through the use of electrical switching polarization in the channel. The gate‐tunable linearity of excitatory and inhibitory functions in photon‐induced short‐term plasticity enables to encode and classify 12 000 images in the Mixed National Institute of Standards and Technology (MNIST) dataset with remarkable accuracy, achieving ≈94%. Additionally, in‐sensor convolution image processing through a network of phototransistors, with five convolutional kernels electrically pre‐programmed into the transistors is demonstrated. The convoluted photocurrent matrices undergo straightforward arithmetic calculations to produce edge and feature‐enhanced scenarios. The findings demonstrate the potential of ferroelectric α‐In2Se3 for highly compact and efficient retinomorphic hardware implementation, regardless of ambipolar transport in the channel.
Injectable, Antioxidative, and Tissue‐Adhesive Nanocomposite Hydrogel as a Potential Treatment for Inner Retina Injuries
Authors: Liu Yi‐Chen , Lin Yi‐Ke , Lin Yu‐Ting , Lin Che‐Wei , Lan Guan‐Yu , Su Yu‐Chia , Hu Fung‐Rong , Chang Kai‐Hsiang , Chen Vincent , Yeh Yi‐Cheun , Chen Ta‐Ching , Yu Jiashing 
Published: January 2024

AbstractReactive oxygen species (ROS) have been recognized as prevalent contributors to the development of inner retinal injuries including optic neuropathies such as glaucoma, non‐arteritic anterior ischemic optic neuropathy, traumatic optic neuropathy, and Leber hereditary optic neuropathy, among others. This underscores the pivotal significance of oxidative stress in the damage inflicted upon retinal tissue. To combat ROS‐related challenges, this study focuses on creating an injectable and tissue‐adhesive hydrogel with tailored antioxidant properties for retinal applications. GelCA, a gelatin‐modified hydrogel with photo‐crosslinkable and injectable properties, is developed. To enhance its antioxidant capabilities, curcumin‐loaded polydopamine nanoparticles (Cur@PDA NPs) are incorporated into the GelCA matrix, resulting in a multifunctional nanocomposite hydrogel referred to as Cur@PDA@GelCA. This hydrogel exhibits excellent biocompatibility in both in vitro and in vivo assessments, along with enhanced tissue adhesion facilitated by NPs in an in vivo model. Importantly, Cur@PDA@GelCA demonstrates the potential to mitigate oxidative stress when administered via intravitreal injection in retinal injury models such as the optic nerve crush model. These findings underscore its promise in advancing retinal tissue engineering and providing an innovative strategy for acute neuroprotection in the context of inner retinal injuries.
Nanotextile 100% Si Anodes for the Next Generation Energy‐Dense Li‐ion Batteries
Authors: Pendashteh Afshin , Tomey Rafael , Vilatela Juan J. 
Published: January 2024

AbstractCombined with other materials and device improvements, Si anodes can provide a step change in Lithium‐ion battery properties, enabling cell energy density to exceed 400 Wh kg−1. Freestanding, large‐area anodes of 100% Si produced by a slurry‐free method without carbon or binders are introduced. Their structure, a dense network of interconnected high aspect ratio Si nanowires (Si NWs), is analogous to a nanotextile and provides handling like paper. In conventional liquid electrolytes, the anode capacity is 2500 mAh g−1 at high mass loadings (e.g., 6.6 mAh cm−2), and cycling stability is 76% after 200 deep cycles, and 100% after 1800 cycles when cycled at 1000 mAh g−1. The nanowire network structure reduces junction resistance between particles and prevents any pulverization upon cycling. Combined impedance and composition‐selective electron microscopy demonstrate that capacity fading is exclusively through the progressive increase of SEI thickness and resistance. Full cell capacity with NMC811 translates into an energy density of 420 Wh kg−1 at the true cell level.
Single‐Atom Immobilization Boosting Oxygen Redox Kinetics of High‐Entropy Perovskite Oxide Toward High‐Performance Lithium‐Oxygen Batteries
Authors: Du Dayue , He Hanna , Zheng Ruixin , Zeng Li , Wang Xinxiang , Shu Chaozhu , Zhang Chuhong 
Published: January 2024

AbstractUnderstanding and modulating the unique electronic interaction between single‐metal atoms and high entropy compounds are of great significance to enable their high‐efficiency oxygen electrocatalysis for aprotic lithium‐oxygen (Li‐O2) batteries. Herein, a novel bi‐functional electrocatalyst is for the first time created by immobilizing single‐atom ruthenium (Ru) on lanthanum‐based high entropy perovskite oxide La(Mn0.2Co0.2Fe0.2Ni0.2Cr0.2)O3 (Ru@HEPO), which demonstrates high activity and stability in Li‐O2 batteries. The heteronuclear coordination between single‐atom Ru and HEPO facilitates fast electron transfer from Ru to HEPO by establishing Ru‐O‐M (M stands for Mn, Co, Fe, Ni) bridges, which well redistributes electrons within the Ru@HEPO hence significantly improving its interfacial charge transfer kinetics and electrocatalytic activity. Additionally, the strong electron coupling between Ru and Mn atoms enhances the hybridization between Mn 3d and O 2p orbitals, which promotes the inherent affinity of Ru@HEPO toward the LiO2 intermediate, thereby reducing the reaction energy barrier of the oxygen electrode. As a result, the Ru@HEPO‐based Li‐O2 batteries deliver remarkable electrochemical performances, such as high energy efficiency (87.3% at 100 mA g−1), excellent rate capability (low overpotential of 0.52 V at 100 mA g−1) and durable cyclability (345 cycles at 300 mA g−1). This work opens up a promising avenue for the development of high entropy‐based electrocatalysts for Li‐O2 batteries by precisely tailoring the electronic distributions at an atomic scale.
Long‐lifespan Zinc‐ion Capacitors Enabled by Anodes Integrated with Interconnected Mesoporous Chitosan Membranes through Electrophoresis‐driven Phase Separation
Authors: Wang Ruoyu , Wang Wenqiang , Sun Ming , Hu Yanjie , Wang Gengchao 
Published: January 2024

AbstractThe advancement of highly secure and inexpensive aqueous zinc ion energy storage devices is impeded by issues, including dendrite growth, hydrogen evolution and corrosion of zinc anodes. It is essential to modify the interface of zinc anodes that homogenizes ion flux and facilitates highly reversible zinc planarized deposition and stripping. Herein, by coupling zinc ion coordination with acid‐base neutralization under the driving of electrophoresis, manageable mesoscopic phase separation for constructing chitosan frameworks was achieved, thereby fabricating interconnected mesoporous chitosan membranes based heterogeneous quasi‐solid‐state electrolytes integrated with anodes. The framework is constructed by twisted chitosan nanofiber bundles, forming a three‐dimensional continuous spindle‐shaped pore structure. With this framework, the electrolyte provides exceptional ion conductivity of 25.1 mS cm−1, with a puncture resistance strength of 2.3 GPa. In addition, the amino groups of chitosan molecule can make the surface of the framework positively charged. Thus, reversible zinc planarized deposition is successfully induced by the synergistic effect of stress constraint and electrostatic modulation. As a result, as‐assembled zinc ion capacitor has an excellent cycle life and sustains the capacity by over 95 % after 20000 cycles at a current density of 5 A g−1. This research presents a constructive strategy for stable electrolytes‐integrated zinc anodes.
Water‐Resistance‐Based S‐Scheme Heterojunction for Deep Mineralization of Toluene
Authors: Li Yuhan , Chen Bangfu , Liu Li , Zhu Bicheng , Zhang Dieqing 
Published: January 2024

AbstractDeep mineralization of low concentration toluene (C7H8) is one of the most significant but challenging reactions in photocatalysis. It is generally assumed that hydroxyl radicals (⋅OH) as the main reactive species contribute to the enhanced photoactivity, however, it remains ambiguous at this stage. Herein, a S‐scheme ZnSn(OH)6‐based heterojunction with AlOOH as water resistant surface layer is in situ designed for tuning the free radical species and achieving deep mineralization of C7H8. By employing a combination of in situ DRIFTS and materials characterization techniques, we discover that the dominant intermediates such as benzaldehyde and benzoic acid instead of toxic phenols are formed under the action of holes (h+) and superoxide radicals (⋅O2−). These dominant intermediates turn out to greatly decrease the ring‐opening reaction barrier. This study offers new possibilities for rationally tailoring the active species and thus directionally producing dominant intermediates via designing water resistant surface layer.
Topologically Invisible Defects in Chiral Mirror Lattices
Authors: Coutant Antonin , Zheng Li‐Yang , Achilleos Vassos , Richoux Olivier , Theocharis Georgios , Pagneux Vincent 
Published: January 2024

AbstractOne of the hallmark of topological insulators is having conductivity properties that are unaffected by the possible presence of defects. In this work, by going beyond backscattering immunity and topological invisibility across defects or disorder is obtained. Using a combination of chiral and mirror symmetry, the transmission coefficient is guaranteed to be unity. Importantly, but no phase shift is induced making the defect completely invisible. Many lattices possess the chiral‐mirror symmetry, and the principle is chosen to be demonstrated on an hexagonal lattice model with Kekulé distortion displaying topological edge waves, and analytically and numerically is shown that the transmission across symmetry preserving defects is unity. Then this lattice in an acoustic system is realized, and the invisibility is confirmed with numerical experiments. It is foreseen that the versatility of the model will trigger new experiments to observe topological invisibility in various wave systems, such as photonics, cold atoms or elastic waves.
Visualization of poikilocytosis as an emerging erythrocytic biomarker for fish health assessment
Authors: Bardhan Avishek , Abraham Thangapalam Jawahar , Das Ratnapriya , Patil Prasanna Kumar 
Published: January 2024

AbstractFish health assessment is essential for maintaining sustainable aquatic ecosystems and ensuring the well‐being of wild and farmed fish populations. Hematological parameters are crucial indicators of fish health, with poikilocytosis emerging as a fundamental marker with significant diagnostic value. Poikilocytosis refers to abnormally shaped erythrocytes in bloodstream, reflecting underlying physiological and pathological conditions. Poikilocytosis can occur in various fish species and can be influenced by environmental stressors, infectious agents, nutritional deficiencies, and exposure to pollutants. Morphological alterations in erythrocytes, such as acanthocytes, echinocytes, dacrocytes, schistocytes, spherocytes, and codocytes are common poikilocytes in fish. Understanding the relationship between poikilocytosis and fish health has important implications for disease diagnosis, monitoring, surveillance, and management. By quantifying poikilocytic changes, researchers and veterinarians can differentiate normal variations from pathological conditions, facilitating targeted interventions and treatment strategies. While most studies have focused on heavy metal toxicity, stressors, nutritional deficiencies, pollutants, and therapeutics, the etiological induction of poikilocytosis in fish health has been overlooked. Nonetheless, poikilocytosis remains a valuable biomarker for assessing fish health and their environment. This review highlights piscine poikilocytosis as a significant fish hematological biomarker and its importance in understanding their health and culture conditions.
Metal‐Free Heterogeneous Photocatalysis for Carbocarboxylation of Alkenes: Efficient Synthesis of γ‐Amino Carboxylic Derivatives
Authors: Wu Ziwei , Zhai Senmao , Luo Meizhen , Dong Quan , Wu Shiwen , Zheng Meifang 
Published: January 2024

AbstractA metal‐free heterogeneous protocol is established herein for the synthesis of value‐added γ‐amino acid scaffolds via carbocarboxylation of alkenes with CO2 and alkylamines under visible light irradiation. The protocol shows broad substrate scope under mild reaction conditions and good stability of the catalyst for recycle tests. Moreover, the methodology could be feasible to the late‐stage derivatization of several natural products, enriching the chemical arsenal for practical application.
Ersatzneubau Strombrückenzug Magdeburg
Authors: Burgard Stefan , Eins Karsten , Anistoroaiei Christian , Schulz Stefan 
Published: January 2024

AbstractDas Vorhaben „Ersatzneubau Strombrückenzug“ soll die vorhandene Brückenverbindung der bestehenden Anna‐Ebert‐Brücke ersetzen. Diese weist aufgrund des Hochwassers 2013 einen irreversiblen und nicht reparablen statischen Totalschaden auf und muss zwingend umgehend und schnellstmöglich durch den Ersatzneubau entlastet werden. Herzstück der innerstädtischen Neubauplanung aus zwei Brückenbauwerken und sechs Knotenpunkten ist die Schrägseilbrücke über die Alte Elbe, bei welcher aufgrund ihrer Lage im FFH‐Gebiet der Alten Elbe strenge Auflagen hinsichtlich der Montagetechnologie zu berücksichtigen waren.
Automatisierte, BIM‐basierte Ökobilanzierung am Beispiel des Infrastrukturbaus
Authors: Hermann Felix , Max Paul Christian , Kunz Matthias 
Published: January 2024

AbstractEin großer Teil der CO2‐Emissionen geht auf die Baubranche zurück. Das größte Potenzial, um diese zu reduzieren, besteht in den frühen Planungsphasen. Die Grundlage für ökologische Optimierungen sind Ökobilanzen (Life Cycle Assessment). Dennoch werden sie v. a. im Infrastrukturbau nur selten erstellt, weil sie mit einem hohen Aufwand verbunden sind und bestehende BIM‐LCA‐Tools eine Vielzahl an BIM‐Modellen nicht verarbeiten können. Nun hat ein Team bei AFRY Deutschland die Methode BIMetrix entwickelt, mit der sich LCAs auch für Hunderte von BIM‐Modellen automatisiert erstellen und dreidimensional visualisieren lassen. Sie wurde bereits erfolgreich in einem realen Pilotprojekt der Deutschen Bahn eingesetzt und validiert. Die Methode eröffnet allen Bereichen des Bauwesens die Möglichkeit, CO2‐Emissionen gezielt zu reduzieren.
Conductive MOFs: Synthesis and Applications in Supercapacitors and Batteries
Authors: Duan Pan , Dai Wenlei , Wang Zixuan , Chen Ming , Niu Liang , Wu Taizheng , Zeng Liang , Feng Guang 
Published: January 2024

AbstractConductive metal‐organic frameworks (c‐MOFs) have uniform, adjustable pore sizes and customizable functional groups and excellent electrical conductivity, making them promising electrode materials for electrochemical energy storage. However, the synthesis of high crystallinity c‐MOFs remains a significant challenge. The purpose of this review is to provide guidance for the synthesis of high crystallinity c‐MOFs and emphasize their applications in the field of energy storage. We begin with reviewing the influence of various reaction conditions on the morphology, size, and crystallinity of c‐MOFs, and then summarize the current work on c‐MOFs in the field of electrochemical energy storage from both experiment and modeling. Furthermore, the existing issues are discussed in the development of c‐MOFs and the primary directions for future research.
In situ Electrolyte Design: Understanding the Prospects and Limitations of a High Capacity Ca(BH4)2 Anode for All Solid State Batteries
Authors: Chen Yixin , Sakamoto Ryo , Inoishi Atsushi , Okada Shigeto , Sakaebe Hikari , Albrecht Ken , Gregory Duncan H. 
Published: January 2024

AbstractAll‐solid‐state batteries have gained considerable attention due to their high safety and energy density. However, solid state electrolytes which contribute to the ionic conductivity component of a composite electrode, are not utilized during the electrode reaction and cannot directly contribute to capacity. This study focuses on decreasing the amount of electrolyte in the electrode by utilizing Ca(BH4)2 as an active electrode material. In this work, the charge‐discharge properties of Ca(BH4)2 as an electrode material were determined for the first time. The lithiation of the Ca(BH4)2 anode creates LiBH4 within the electrode mixture, providing new Li‐ion conduction pathways within the composite electrode in situ. An electrode fabricated only from Ca(BH4)2 and acetylene black (AB) showed an initial capacity of 473 mAh g−1 at 120 °C, which is comparable to the performance obtained from a composite electrode additionally containing electrolyte. Evidently, Ca(BH4)2 is a promising candidate negative electrode for increased energy density all‐solid‐state Li‐ion batteries.
Evidence for cytochrome P450 3A4‐mediated metabolic activation of SCO‐267
Authors: Li Cui , Li Xiaokun , Fan Ali , He Ning , Wu Dongmei , Yu Hongyan , Wang Kun , Jiao Weijie , Zhao Xu 
Published: January 2024

AbstractSCO‐267 is a potent G‐protein‐coupled receptor 40 agonist that is undergoing clinical development for the treatment of type 2 diabetes mellitus. The current work was undertaken to investigate the bioactivation potential of SCO‐267 in vitro and in vivo. Three SCO‐267‐derived glutathione (GSH) conjugates (M1–M3) were found both in rat and human liver microsomal incubations supplemented with GSH and nicotinamide adenine dinucleotide phosphate. Two GSH conjugates (M1–M2) together with two N‐acetyl‐cysteine conjugates (M4–M5) were detected in the bile of rats receiving SCO‐267 at 10 mg/kg. The identified conjugates suggested the generation of quinone‐imine and ortho‐quinone intermediates. CYP3A4 was demonstrated to primarily catalyze the bioactivation of SCO‐267. In addition, SCO‐267 concentration‐, time‐, and NADPH‐dependently inactivated CYP3A in human liver microsomes using testosterone as a probe substrate, along with KI and kinact values of 4.91 μM and 0.036 min−1, respectively. Ketoconazole (a competitive inhibitor of CYP3A) displayed no significant protective effect on SCO‐267‐induced CYP3A inactivation. However, inclusion of GSH showed significant protection. These findings revealed that SCO‐267 undergoes a facile CYP3A4‐catalyzed bioactivation with the generation of quinone‐imine and ortho‐quinone intermediates, which were assumed to be involved in SCO‐267 induced CYP3A inactivation. These findings provide further insight into the bioactivation pathways involved in the generation of reactive, potentially toxic metabolites of SCO‐267. Further studies are needed to evaluate the influence of SCO‐267 metabolism on the safety of this drug in vivo.
Factors contributing to the burnout of the faculties of a medical university in Iran: A cross‐sectional study
Authors: Ghahramani Sulmaz , Moghadami Mohsen , Omidifar Navid , Tabatabaei Seyed Mohamad Mehdi , Sayari Mohammad , Bagheri Lankarani Kamran 
Published: January 2024

AbstractBackground and aimsFaculty members confront a variety of obstacles over time, the most recent of which is the coronavirus disease 2019 pandemic, which may increase their vulnerability to burnout (BO). This study aims to examine BO in medical school faculties, as well as the factors that lead to BO and well‐being in them.MethodsThis cross‐sectional study was conducted in 2021 using online questionnaires completed by 222 faculty members of a medical university in Iran. The Maslach Burnout Inventory‐Human Services Survey (MBI‐HSS) and the Well‐being index (WBI) were used. Additionally, we gathered individual‐level profiles (demographic, well‐being) and occupational information (job profile, attitude toward work).ResultsA total of 60 (27%) faculties reported having high BO, and 112 (50.5%) reported having low well‐being. Being female (odds ratio, OR = 2.69), having time to spend with the family (OR = .26), the intent of turnover (OR = 8.65), job recommendation to the offspring (OR = .26), and experiencing violence last year (OR = 2.97) were some of the individual‐level factors and job‐related attitudes associated with a higher BO. In the neural network for BO, the most important variables were the intention of turnover, followed by adequate family time.ConclusionOne third of the responding faculty reported severe BO, and BO was found to be significantly associated with lower well‐being. The increased levels of BO and a decreased experience of well‐being were both associated with a higher intention of turnover. According to the study, it is important to pay attention to both clinical and nonclinical field faculty members, female faculty members, those who have a high workload, and members who have experienced violence in the workplace. By acknowledging the unique challenges and experiences faced by these individuals, tailored measures can be developed to address their specific concerns and foster a supportive and inclusive environment.
Association between functional network connectivity, retina structure and microvasculature, and visual performance in patients after thalamic stroke: An exploratory multi‐modality study
Authors: Ye Chen , Kwapong William Robert , Tang Biqiu , Liu Junfeng , Tao Wendan , Lu Kun , Pan Ruosu , Wang Anmo , Liao Lanhua , Yang Tang , Cao Le , Wang Youjie , Jiang Shuai , Zhang Xuening , Liu Ming , Wu Bo 
Published: January 2024

AbstractBackground and objectiveNeuro‐ophthalmologic symptoms and retinal changes have been increasingly observed following thalamic stroke, and there is mounting evidence indicating distinct alterations occurring in the vision‐related functional network. However, the intrinsic correlations between these changes are not yet fully understood. Our objective was to explore the altered patterns of functional network connectivity and retina parameters, and their correlations with visual performance in patients with thalamic stroke.MethodsWe utilized resting‐state functional MRI to obtain multi‐modular functional connectivity (FC), and optical coherence tomography‐angiography to measure various retina parameters, such as the retinal nerve fiber layer (RNFL), ganglion cell‐inner plexiform layer (GCIPL), superficial vascular complex (SVC), and deep vascular complex. Visual acuity (VA) was used as a metric for visual performance.ResultsWe included 46 patients with first‐ever unilateral thalamic stroke (mean age 59.74 ± 10.02 years, 33 males). Significant associations were found between FC of attention‐to‐default mode and SVC, RNFL, and GCIPL, as well as between FC of attention‐to‐visual and RNFL (p < .05). Both RNFL and GCIPL exhibited significant associations with FC of visual‐to‐visual (p < .05). Only GCIPL showed an association with VA (p = .038). Stratified analysis based on a disease duration of 6 months revealed distinct and significant linking patterns in multi‐modular FC and specific retina parameters, with varying correlations with VA in each subgroup.ConclusionThese findings provide valuable insight into the neural basis of the associations between brain network dysfunction and impaired visual performance in patients with thalamic stroke. Our novel findings have the potential to inform future targeted and individualized therapies. However, further comprehensive studies are necessary to validate our results.