bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the prioritisation of sleep, diet, and physical activity as pillars of health: correlates and associations with health behaviours in Australian adults
Authors: Gupta Charlotte C , Duncan Mitch J , Ferguson Sally A , Rebar Amanda , Vandelanotte Corneel , Sprajcer Madeline , Khalesi Saman , Booker Lauren A. , Rampling Caroline , Rigney Gabrielle , Vincent Grace E 
Published: December 2023

Abstract
Background
Chronic disease is the leading cause of death globally. Sleep, diet, and physical activity are modifiable health behaviours that are key for reducing the burden of chronic disease. These health behaviours are collectively termed ‘The 3 Pillars of Health’ and are critical for populations who are at risk of poor health. Shiftworkers are one such at-risk population. To target behavioural change it is critical to first understand which of these health behaviours Australians currently prioritise. Therefore, this study aimed to investigate how Australians (including shift workers) prioritise sleep, physical activity, and diet, and examine the associations with correlates of health behaviours.

Methods
Two cohorts of Australian adults were sampled. A cohort of 1151 Australian adults (54% female, aged 18–65 years) including employed (in any work schedule), unemployed, studying, and retired completed a phone interview. A cohort of 533 Australian shiftwork-only adults (76% female, 18–72) completed an online survey. All participants were asked which health behaviour (sleep, physical activity, or diet) they prioritised in their own life. Behavioural correlates of sleep, diet, and physical activity (sleep duration, frequency of moderate to physical activity, healthy dietary behaviour), and years of shiftwork experience were also collected. Multinomial logistic regressions were used to investigate the association between the highest prioritised pillar of health and the behavioural correlates.

Results
Diet was prioritised by the Australian adults (49%), whereas sleep was prioritised by the shiftwork-only sample (68%). Australian adults who prioritised diet were significantly more likely to report diets with less fast-food consumption (p < 0.002) and more fruit consumption (p < 0.002) compared to those that prioritised sleep. For the shiftwork-only sample, those with 16–30 years of shiftwork experience were significantly more likely to prioritise sleep compared to diet (p < 0.05). However, prioritising sleep was not associated with meeting the sleep duration recommendations in the shiftwork-only sample.

Conclusions
Across two cohorts of Australians, prioritisation of health behaviour was only associated with actual behaviour for diet. This may reflect different motivations for prioritising different health behaviours, in addition to different capabilities to change different health behaviours. Future research should include longitudinal methodologies to understand how behaviour prioritisation changes over work- and life-span, and any associations with actual health behaviour.
Exploring perceptions and experiences of stigma in Canada during the COVID-19 pandemic: a qualitative study
Authors: Cooper Jeanette , Theivendrampillai Suvabna , Lee Taehoon , Marquez Christine , Lau Michelle Wai Ki , Straus Sharon E. , Fahim Christine ,   in partnership with the Chinese Canadian National Council Toronto Chapter,   the Chinese Canadian National Council for Social Justice
Published: December 2023

Abstract
Background
The COVID-19 pandemic fueled stigmatization and discrimination, particularly towards individuals of Chinese or East Asian ethnicity. We conducted interviews with members of the public in Canada in order to describe and understand stigma perceptions and experiences during the COVID-19 pandemic.

Methods
We used a phenomenological approach to describe stigma experiences of Canadian residents during the COVID-19 pandemic and compared the stigma perceptions and experiences of East Asian and non-East Asian individuals. Participants were invited to take part in a single, semi-structured interview. The interview guide was rooted in the Health Stigma and Discrimination Framework (HSDF). Interviews were conducted in English, Mandarin, and Cantonese. Following participant consent, interviews were audio recorded and transcribed verbatim. Data were double coded and analyzed using qualitative content analysis guided by a framework approach.

Results
A total of 55 interviews were conducted between May and December 2020. Fifty-five percent of the sample identified as East Asian, 67.3% identified as women, and mean age was 52 years (range 20–76). Fear of infection, fear of social and economic ramifications, and blame for COVID-19 were reported drivers of stigma. Participants described preexisting perceptions on cultural norms and media influence as facilitators of stigma that propagated harmful stereotypes, particularly against Chinese and East Asian individuals. Participants observed or experienced stigmatization towards place of residence, race/ethnicity, culture, language, occupation, and age. Stigma manifestations present in the public and media had direct negative impacts on East Asian, particularly Chinese, participants, regardless of whether or not they personally experienced discrimination.

Conclusions
We used the HSDF as a rooting framework to describe perceptions and impact of stigma, particularly as they related to race/ethnicity-based stigmatization in Canada. Participants reported a number of drivers and facilitators of stigma that impacted perceptions and experiences. These findings should be used to develop sustained strategies to mitigate stigma during public health emergencies or other major crises.
Management of RANKL-mediated Disorders With Denosumab in Children and Adolescents: A Global Expert Guidance Document
Authors: Vanderniet Joel A , Szymczuk Vivian , Högler Wolfgang , Beck-Nielsen Signe S , Uday Suma , Merchant Nadia , Crane Janet L , Ward Leanne M , Boyce Alison M , Munns Craig F 
Published: December 2023

Abstract

Context
Denosumab is an effective treatment for many receptor activator of nuclear factor kappa-B ligand (RANKL)-mediated disorders but there are potential safety considerations and limited data to guide its use in children and adolescents.

Objective
This document seeks to summarize the evidence and provide expert opinion on safe and appropriate use of denosumab in pediatric RANKL-mediated disorders.

Participants
Ten experts in pediatric bone and mineral medicine from 6 countries with experience in the use of denosumab participated in the creation of this document.

Evidence
Data were sourced from the published literature, primarily consisting of case reports/series and review articles because of the lack of higher level evidence. Expert opinion of the authors was used substantially when no published data were available.

Conclusion
Denosumab is an effective treatment for RANKL-mediated disorders in children and adolescents but is often not curative and, in some cases, is best used in conjunction with surgical or other medical treatments. Careful multidisciplinary planning is required to define the goals of treatment and expert oversight needed to manage the risk of mineral abnormalities. Substantive, collaborative research efforts are needed to determine optimal treatment regimens and minimize risks.
From Social to Mathematical Science: Transforming Economics at the École des Hautes Études en Sciences Sociales, 1956–85
Authors: Benest Serge 
Published: December 2023

Abstract
Within the French academic landscape, the École des hautes études en sciences sociales (EHESS) stands out as the only institution exclusively devoted to the social sciences. Since its creation in 1947, it has claimed a scientific agenda based on interdisciplinary approaches. Originally, economists had a prominent place within the institution. The so-called realist economists endorsed an empirical and interdisciplinary approach and rejected mathematical and abstract approaches. Yet, in the past fifty years or so, most EHESS economists have conducted model-oriented research and adopted international standards. That transformation was accomplished despite strong opposition from noneconomist social scientists. This article follows the chaotic journey of economics at the EHESS and shows that local institutional configurations shaped the shift in economic methods.
Evaluation of Cytotoxicity of 1H-1,2,4-Triazole-3-carboxamide Derivatives in Various Cancer Cell Lines using MTT Assay: Synthesis, Characterization and Molecular Docking Studies
Authors: Sharma Dipesh Kumar , Singh Surabhi 
Published: December 2023

The pursuit of discovering efficacious novel anticancer agents is an ongoing and perpetual endeavour. The ongoing research endeavour involves the discovery of a new set of various substituted 1,2,4-triazole carboxamide derivatives. The synthetic process involves multiple steps: converting thiooxamic acid ethyl ester to ethyl b-N-boc-oxalamidrazone (2), preparing ethyl esters of 5-substituted 1,2,4-triazole-3-carboxylic acid (3) and synthesizing 5-substituted 1,2,4-triazole-3-carboxylic acid amides (4a-n) using potassium tert.-butoxide. The resulting compounds are characterized using 1H and 13C NMR spectroscopy and HRMS. Molecula docking experiments were performed using the synthesized compounds against two cancer targets, viz. EGFR (6LUD) and CDK-4 (7SJ3). The compounds were assessed for their anticancer potential against four different cancer cell lines, namely non-small cell lung cancer (A-549), pancreatic cancer (PANC-1), colorectal cancer (HCT-116) and cervical cancer (HaLa) cell lines. Additionally, a normal human embryonic kidney cell line (HEK-293) was used for comparison. The results obtained from molecular docking analysis demonstrated that the 1,2,4-triazole carboxamides (4c, 4e, 4h, 4m and 4n) exhibited more favourable binding interactions compared to the ligands that were co-crystallized. All the compounds exhibited a satisfactory cytotoxicity profile in comparison to the reference drug doxorubicin. Among the compounds that tested, it was observed that compounds 4e and 4m displayed the most pronounced inhibitory activity across all the cell lines that were tested.
Profiling of adenine‐derived signaling molecules, cytokinins, in myotubes reveals fluctuations in response to lipopolysaccharide‐induced cell stress
Authors: Tobin Stephanie W. , Seneviratne Dev , Phan Lorna , Seegobin Mark , Rico Alexander L. , Westby Beth , Kisiala Anna , Martic Sanela , Brunetti Craig R. , Emery R. J. Neil 
Published: December 2023

AbstractCytokinins (CTKs) are a diverse collection of evolutionarily conserved adenine‐derived signaling molecules classically studied as phytohormones; however, their roles and production have been less studied in mammalian systems. Skeletal muscles are sensitive to cellular cues such as inflammation and in response, alter their secretome to regulate the muscle stem cell and myofiber niche. Using cultured C2C12 muscle cells, we profiled CTK levels to understand (1) whether CTKs are part of the muscle secretome and (2) whether CTKs are responsive to cellular stress. To induce cellular stress, C2C12 myotubes were treated with lipopolysaccharides (LPS) for 24 h and then media and cell fractions were collected for ultra high‐performance liquid chromatography tandem mass spectrometry with electrospray ionization (UHPLC‐(ESI+)‐HRMS/MS) for metabolomics and CTK profiling. Across LPS‐treated and control cells, 11 CTKs were detected in the extracellular space while 6 were detected intracellularly. We found that muscle cells are enriched in isopentenyladenine (iP) species (from free base, riboside to nucleotide forms), and that extracellular levels are increased after LPS treatment. Our study establishes that muscle cells express various forms of CTKs, and that CTK levels are responsive to LPS‐induced cell stress, suggesting a role for CTKs in intra‐ and extracellular signaling of mammalian cells.
Runx1 is upregulated by STAT3 and promotes proliferation of neonatal rat cardiomyocytes
Authors: Suzuki Shota , Tanaka Shota , Kametani Yusuke , Umeda Ayaka , Nishinaka Kosuke , Egawa Kaho , Okada Yoshiaki , Obana Masanori , Fujio Yasushi 
Published: December 2023

AbstractThough it is well known that mammalian cardiomyocytes exit cell cycle soon after birth, the mechanisms that regulate proliferation remain to be fully elucidated. Recent studies reported that cardiomyocytes undergo dedifferentiation before proliferation, indicating the importance of dedifferentiation in cardiomyocyte proliferation. Since Runx1 is expressed in dedifferentiated cardiomyocytes, Runx1 is widely used as a dedifferentiation marker of cardiomyocytes; however, little is known about the role of Runx1 in the proliferation of cardiomyocytes. The purpose of this study was to clarify the functional significance of Runx1 in cardiomyocyte proliferation. qRT‐PCR analysis and immunoblot analysis demonstrated that Runx1 expression was upregulated in neonatal rat cardiomyocytes when cultured in the presence of FBS. Similarly, STAT3 was activated in the presence of FBS. Interestingly, knockdown of STAT3 significantly decreased Runx1 expression, indicating Runx1 is regulated by STAT3. We next investigated the effect of Runx1 on proliferation. Immunofluorescence microscopic analysis using an anti‐Ki‐67 antibody revealed that knockdown of Runx1 decreased the ratio of proliferating cardiomyocytes. Conversely, Runx1 overexpression using adenovirus vector induced cardiomyocyte proliferation in the absence of FBS. Finally, RNA‐sequencing analysis revealed that Runx1 overexpression induced upregulation of cardiac fetal genes and downregulation of genes associated with fatty acid oxidation. Collectively, Runx1 is regulated by STAT3 and induces cardiomyocyte proliferation by juvenilizing cardiomyocytes.
Electro-chemo-mechanical properties of anodic oxide (passive) films formed on Cu, Ni and Fe
Authors: Seo Masahiro 
Published: December 2023

Abstract
Electro-chemo-mechanical properties of anodic oxide (passive) films formed on metals have been reviewed focusing on the results of stress variations caused by anodic oxidation of Cu, Ni, and Fe thin film electrodes in deaerated pH 8.4 borate buffer solution at 25 °C. The surface stress varies toward compressive direction due to adsorption of OH on Cu from aqueous solution as well as adsorption of oxygen on metals from gas phase. The stresses are generated with the growth of three-dimensional anodic oxide films on metals. The magnitude and sign (tensile or compressive) of the intrinsic film stress were determined by taking the residual stress of the substrate and the dielectrostriction into consideration. The tensile or compressive intrinsic film stress depends on p-type or n-type semiconductive properties of the anodic oxide films, which is explained in terms of the void formation or oxide formation in the metal side at the metal/film interface. Furthermore, the stress variation toward compressive direction during cathodic reduction of the anodic oxide films is explained in terms of the volume expansion due to the formation of intermediate species.
CO2 adsorption behavior of a highly-microporous KOH-activated carbon obtained from rice husk waste: kinetic and equilibrium studies
Authors: Granados-Correa Francisco , Gutiérrez-Bonılla Elvira , Jiménez-Reyes Melania , Roa-Morales Gabriela , Balderas-Hernández Patricia 
Published: December 2023

Abstract
In this study, rice husk was the precursor for a KOH-activated carbon with high surface area and high micro-porosity. CO2 adsorption capacity of this material was measured by thermogravimetric analysis. The CO2 adsorption kinetic showed that equilibrium was reached 30 min after the solid-gas phases came into contact and is well-described by the pseudo-first order model (R
2 > 0.99 and 95 % confidence level). Intraparticle diffusion model revealed multilinearity over the CO2 adsorption range. Isotherm data at 25, 35, and 45 °C were well-fitted by the Freundlich model, revealing the adsorbent’s surface heterogeneity and the exothermic behavior of the process. The material reached a maximum CO2 adsorption capacity of 2.54 mmol/g. A comparison with literature data showed a good agreement.
Improved kernel density peaks clustering for plant image segmentation applications
Authors: Bi Jiaze , Zhang Pingzhe , Gao Yujia , Dong Menglong , Zhuang Yongzhi , Liu Ao , Zhang Wei , Chen Yiqiong 
Published: December 2023

Abstract
In order to better solve the shortcomings of the k-means clustering method and density peaks clustering (DPC) method in agricultural image segmentation, this work proposes a method to divide points in a high-dimensional space, and a clustering method is obtained to divide crops and soil. In the process of assigning points in the DPC method, if a point is divided incorrectly, a series of points may be assigned to a cluster that is not related to it. In response to this problem, this study uses the decision graph to select the centroids, and uses Gaussian kernel to map the data to the high-dimensional space, each centroid searches for the most relevant points in the high-dimensional space until a temporary boundary point is found to stop the first assignment strategy, and then the points that are not clustered are assigned to the correct cluster to complete the clustering. The experimental results show that the proposed method has a better clustering effect through experiments on multiple artificial datasets and UCI datasets, compared with other clustering methods, and finally applied to plant image segmentation.
Switchable radiative cooling and solar heating for sustainable thermal management
Authors: Yoo Myung Jin , Pyun Kyung Rok , Jung Yeongju , Lee Minjae , Lee Jinwoo , Ko Seung Hwan 
Published: December 2023

Abstract
Radiative thermal management technologies that utilize thermal radiation from nano/microstructure for cooling and heating have gained significant attention in sustainable energy research. Passive radiative cooling and solar heating operate continuously, which may lead to additional heating or cooling energy consumption due to undesired cooling or heating during cold nighttime/winters or hot daytime/summers. To overcome the limitation, recent studies have focused on developing radiative thermal management technologies that can toggle radiative cooling on and off or possess switchable dual cooling and heating modes to realize sustainable and efficient thermal management. This review will explore the fundamental concepts of radiative thermal management and its switching mechanisms, utilizing novel systems composed of various materials and nano/microstructures. Additionally, we will delve into the potential future research directions in radiative thermal management technologies.
Numerical simulation and analysis of Airy's-type equation
Authors: Alderremy Aisha A. , Yasmin Humaira , Shah Rasool , Mahnashi Ali M. , Aly Shaban 
Published: December 2023

Abstract
In this article, we propose a novel new iteration method and homotopy perturbation method (HPM) along with the Elzaki transform to compute the analytical and semi-analytical approximations of fractional Airy’s-type partial differential equations (FAPDEs) subjected to specific initial conditions. A convergent series solution form with easily commutable coefficients is used to examine and compare the performance of the suggested methods. Using Maple graphical method analysis, the behavior of the estimated series results at various fractional orders

ς

\varsigma

and its modeling in two-dimensional (2D) and three-dimensional (3D) spaces are compared with actual results. Also, detailed descriptions of the physical and geometric implications of the calculated graphs in 2D and 3D spaces are provided. As a result, the obtained solutions of FAPDEs that are subject to particular initial values quite closely match the exact solutions. In this way, to solve FAPDEs quickly, the proposed approaches are considered to be more accurate and efficient.
Kaufmannswetten in der handelsrechtlichen Praxis, oder: Wie die Briten zum Sport kamen
Authors: Eisenberg Christiane 
Published: December 2023

Zusammenfassung
Der Beitrag befasst sich mit einer in der Forschung bislang vernachlässigten Grundlage des modernen englischen Sportmodells: der Kaufmannskultur des vormodernen Englands. Er analysiert die vertragsrechtliche Problematik, die es englischen Kaufleuten und Händlern seit dem späten Mittelalter zweckmäßig erscheinen ließ, ihre Geschäftsvereinbarungen mit Wetten und Wettkämpfen zu bekräftigen, und er zeigt, wie diese Praktiken zusammen mit weiteren, insbesondere solchen aus dem internationalen Law Merchant, so in den allgemeinen Rechtsrahmen des Königreiches England integriert wurden, dass das kaufmännische Sportmodell verstetigt und verallgemeinert werden konnte.
Psychedelics and schizophrenia: A mystery in history
Authors: Haden Mark , Woods Birgitta Anne , Paschall Sarah A. 
Published: December 2023

AbstractThis analysis of current and historical research and clinical reports observes that the relationship between psychedelics and schizophrenia is complex and there are reports of psychedelics benefiting this population. Specifically, lower doses of psychedelics (mostly LSD) appear to have a potential beneficial impact on the negative symptoms of schizophrenia.
Monitoring temperature and hydration by mortar sensors made of nanomodified Portland cement
Authors: Buasiri Thanyarat , Kothari Ankit , Habermehl-Cwirzen Karin , Krzeminski Lukasz , Cwirzen Andrzej 
Published: December 2023

AbstractMortar beams incorporating carbon nanofibers (CNFs), which were synthesized in situ on Portland cement particles, were used to produce nanomodified Portland cement sensors (SmartCem sensors). SmartCem sensors exhibited an electrical response comparable to a thermistor with a temperature coefficient of resistivity of − 0.0152/ °C. The highest temperature sensing was obtained for the SmartCem sensor, which contained ~ 0.271 wt.% of CNFs. The calculated temperature sensitivity was approximately 11.76% higher in comparison with the mortar beam containing only unmodified Portland cement. SmartCem sensors were used to monitor the cement hydration in large-scale self-compacting concrete beams. The measurements were conducted after casting for 7 days. Additionally, commercially available thermocouple and humidity sensors were used as references. The results showed that changes in electrical resistivity measured by the SmartCem sensor were well aligned with the ongoing hydration processes.
Gastrointestinal Stromal Tumor (GIST) presenting as acute abdomen: Image in surgery
Authors: Med Dheker Touati , Marwa Idani , Mohamed Raouf Ben Othmane , Fahd Khefacha , Nadhem Khelifi , Anis Belhadj , Ahmed Saidani , Faouzi Chebbi 
Published: December 2023

Gastrointestinal stromal tumors originating from the small bowel are uncommon. We present the case of a 45-year-old man with no prior medical or surgical history who presented to our hospital's emergency department with abdominal pain, vomiting, inability to pass gas, and no bowel movements. Physical examination revealed abdominal distention and tenderness. His white blood cell count was 10.9 x 10^3/µl, and hemoglobin levels were 13.3 g/dl.