bluuebunny/crossref_metadata_2025_split huggingface dataset:
Identification of barriers and facilitators of successful interprofessional education (IPE) – a scoping umbrella review / Identifizierung der Einflussfaktoren für die interprofessionelle Ausbildung (IPE) – ein Umbrella Scoping Review
Authors: Handgraaf Marietta , Wallin Jasmin , Groll Christina , Posenau André 
Published: December 2023

Abstract

Objective
The study aims to provide an overview of factors influencing interprofessional education (IPE).

Method
A systematic literature search was performed using the databases MEDLINE, CINAHL, PsycINFO, Embase, and Cochrane Library. Two reviewers conducted the study selection and data analysis. Subsequently, the factors influencing IPE were summarized through qualitative narrative synthesis.

Results
The search yielded 1,040 results, of which 10 studies were ultimately included. The influencing factors that were identified were clustered into three dimensions: learners, educators, and institutions. Reviewing the selected studies, it became evident that all influencing factors are closely interdependent. In the learners’ dimension, the construct of diversity, related to group formation and the strengthening of their sense of belonging, was identified as a facilitating factor for IPE. Thus, it appears that the formation of an interprofessional identity has a positive impact on the constructs mentioned. Moreover, the competence of the educators, and the combination of teaching methods, were crucial factors for sustainable IPE. Institutional support plays a facilitating role.

Conclusion
The overview results of this study can be used to identify areas for improvement and changes in IPE. Crucial for institutions is the support through management and leadership, along with the implementation of effective faculty development concepts. Further research on IPE is needed to extend understanding of the constructs of diversity, team efficiency and interprofessional identity, as well as the respective relations between them.
Medical laboratory technicians’ job satisfaction in Generations X, Y, and Z: Findings from an online survey in Austria / Arbeitszufriedenheit österreichischer biomedizinischer Analytiker*innen in den Generationen X, Y und Z: Ergebnisse einer Online-Umfrage aus Österreich
Authors: Schmidt Diana , Latzke Markus 
Published: December 2023

Abstract

Goal
Medical laboratory technicians (MLTs) play an essential role in health care, and the profession has to deal increasingly with staff shortages. Consequently, retention of employees has become a crucial issue. So far, little attention has been paid to generational differences in factors regarding job satisfaction of MLTs, and comparatively few studies have included the youngest cohort of Generation Z. The aim of this study was to analyse aspects of MLTs’ job satisfaction from a generational perspective and to identify potential for improvement according to the different generations studied.

Methods
A cross-sectional online survey study design was used. A total of 382 MLTs completed the online survey of which 371 met the eligibility criteria and were assigned to one of the three generational cohorts. The analysis focused on several aspects of job satisfaction, the gap between the perceived relevance and realization of these aspects, and factors influencing job satisfaction by generation.

Principal findings
For all aspects of job satisfaction, and across all generations, realization was rated worse than importance. Recognition represents the most important influencing factor for job satisfaction, but other aspects are specifically relevant to one of the three generations, such as relationships for Generation X, meaningful contribution for Generation Y, and income for Generation Z.

Practical applications
The various aspects of job satisfaction show commonalities and differences between the three generations. Employers and professional associations can draw on these findings to positively influence job satisfaction through generation-specific interventions to support this essential healthcare workforce.
Examining the presence of sarcopenia in women with rheumatoid arthritis: Case-control study
Authors: Akar Begum , Calik Bilge Basakci , Kabul Elif Gur , Akbaş Ayşe Nur Bayindir , Cobankara Veli 
Published: December 2023

Abstract

Introduction
The aim of this study was to compare the frequency of sarcopenia, functional status, fear-avoidance behaviors, biopsychosocial status and quality of life in RA women with healthy controls.

Methods
25 RA women and 25 healthy women were included in the study. Definition of sarcopenia was assessed using parameters recommended by the European Working Group on Sarcopenia (EWGSOP): Bioimpedance analysis for muscle mass (body fat ratio, skeletal muscle mass, skeletal muscle mass index); grip and knee extension strength for muscle strength and 4-m course gait speed test for physical performance was applied. Functional status was evaluated with the Health Assessment Questionnaire (HAQ), fear-avoidance behaviors with the Tampa Kinesiophobia Scale (TKS), biopsychosocial status with the Biopsychosocial Questionnaire (BETY-BQ), and quality of life with Short Form-36 (SF-36).

Results
While none of the healthy women had sarcopenia, severe sarcopenia was detected in 7 (28%) of the women with RA. When RA and healthy groups were compared; skeletal muscle mass (p: 0,004); skeletal muscle mass index (p: 0,011); grip strength-right (p:0.001) and left (p:0.001); knee extension strength-right (p:0.001) and left (p:0.001), 4-m course gait speed test (p:0.001), HAQ (p:0.001), TKS (p:0.001), BETY-BQ (p:0.001), SF-36 physical (p:0.001) ve mental component (p:0.001) results were significant in favor of the healthy group while there was no difference in body fat ratio (p>0.05).

Conclusion
In women with RA, the frequency of sarcopenia is higher, and functional status, fear-avoidance behaviors, biopsychosocial status and quality of life are worse than healthy.
Nurses Supporting Harm Reduction: How Take-Home Naloxone is Conceived in the Context of Neoliberalism
Authors: Kusdemir Sibel , Oudshoorn Abe 
Published: December 2023

Introduction – Individuals must be personally invested in their own recovery journey; however, the neoliberal perspective absolves the state of responsibility of this work and makes promotion of health merely an individual action. Naloxone distribution, as a harm reduction strategy, is presented herein as one practice engaged by nurses that demonstrates philosophical tension between neoliberalism and harm reduction.
Background Literature – The research literature supporting the provision of take-home naloxone (THN), non-medically administered, is significant and broad.
Discussion – The problem with neoliberal discourses of constrained healthcare resources in this case is that without broad availability of naloxone, drug poisonings will continue unchecked. There is an ethical call to nurses to support broad distribution of naloxone regardless of the costs involved.
Conclusion – THN is not only a best practice to reduce the harms of substance use, but it is also a political and philosophical act to hand over the control of public health resources to the public.
Impact of advanced maternal age and parity on birth outcome at a tertiary hospital in Nigeria
Authors: Uji Ago Boniface , Etenikang Abeshi Sylvester 
Published: December 2023

Objectives
To assess the impact of advanced maternal age (AMA) and parity on birth outcomes.

Material and Methods
This was a three month retrospective observational study conducted at a tertiary hospital in Calabar, Nigeria. It involved hospital and delivery records of parturients who registered for delivery at this centre. They were grouped into those aged 20–34, and 335 referred to as AMA. The required data for the selected obstetric and neonatal outcomes were entered in Epi Info version 7.2.3 CDC Atlanta, Georgia statistical software for analysis.

Results
The odds for caesarean delivery were 4.42 with a 95% Confidence interval of 2.35–8.31. There were also increased odds of birth asphyxia, postpartum haemorrhage (PPH), and stillbirths. There were no significant differences in the risks for foetal macrosomia, multiple pregnancy, and prematurity.

Conclusion

AMA women were more likely to have caesarean birth, PPH and stillbirths, while their babies were more likely to have birth asphyxia. There is a need for preventive strategies to ameliorate these risks in this group of parturients.
Utility of cerebrospinal fluid protein biomarkers in predicting the outcome of Guillain-Barre syndrome
Authors: Amalakanti Sridhar , Venkata Raman Arepalli Kesava , Priya Jillella Jyothi 
Published: December 2023

Objectives
The study aimed to investigate the potential of peripheral myelin protein 2 (P2) and Alpha B-crystallin (αBC) as predictive biomarkers in Guillain-Barré syndrome (GBS). Given the unpredictability of GBS prognosis, the need for specific and reliable biomarkers for disease development and intensity assessment is crucial.

Material and Methods

A prospective observational study was conducted on a cohort of 220 individuals diagnosed with GBS at a tertiary general hospital in South India. P2 and αBC levels in cerebrospinal fluid (CSF) were quantified using ELISA assay kits. The study spanned from March 2021 to April 2023, with participants aged 18–60 years. The study protocol adhered to ethical standards, and the Brighton criteria were employed for GBS diagnosis. CSF samples were collected at admission and two weeks post-onset. Data analysis utilised SPSS, and statistical significance was set at p < 0.05.

Results

Upon admission, mean P2 levels were 2.2 ± 0.5 ng/mL, and αBC levels were 9.8 ± 2.3 ng/mL. After two weeks, P2 increased to 4.8 ± 0.8 ng/mL, and αBC increased to 15.1 ± 2.3 ng/mL. A positive correlation was observed between the rise in P2 and αBC levels and enhanced muscle strength at 4 weeks and 6 months.

Conclusion

The study suggests a significant increase in P2 and αBC levels in GBS patients, correlating with improved muscle strength. P2 and αBC ratios in CSF between the second and first weeks may serve as prognostic markers for GBS. Limitations include a small sample size and the absence of a control group, necessitating caution in generalizability.
Impact of MDR-1 mutations on HIV viral load and gender-specific effects: Insights from Co-Infection with malaria parasites
Authors: Onwuzurike Peace Amaka , Nkpeh Ushie Simon , Nnaemeka Ilokanuno Chinedu , Okwelogu Izunna Somadina 
Published: December 2023

Objectives
MDR-1 mutations in HIV patients cause a significant increase in viral load due to impaired function of the transporter protein responsible for eliminating drugs from cells. As a result, infected cells show reduced drug removal, leading to elevated viral replication and higher viral load levels in the bloodstream. This poses challenges in HIV treatment, potentially leading to treatment failure and the development of drug-resistant viral strains. Identifying MDR-1 mutations in HIV patients is crucial to optimise treatment approaches, potentially involving alternative medications or combination therapies to overcome drug resistance.

Material and Methods
The study utilised various laboratory techniques to analyse the collected blood samples, including HIV serology using rapid diagnostic kits, viral load estimation using the COBAS® Ampli Prep/COBAS® Taq Man® HIV-1 Test, microscopy for detecting malaria parasites and PCR for characterising Plasmodium species and studying resistance genes.

Results
There is a positive relationship with the viral load when comparing patients who tested negative for MDR-1 mutations to those who tested positive. The p-value for this relationship is stated as <0.001, which means it is less than 0.001. This indicates that the relationship is statistically significant (p < 0.001), and we can conclude that MDR-1 status has a significant impact on viral load. HIV patients with identified MDR-1 mutations have been shown to have a dramatic increase in their viral load than in the absence of the mutation.

Conclusion
In conclusion, this study sheds light on the impact of MDR-1 mutations on HIV viral load, gender-specific effects and their interactions with malaria co-infection. The findings emphasise the importance of personalised treatment strategies for HIV patients, considering genetic variations, gender-specific factors and co-infections to optimise management and improve health outcomes in regions with overlapping disease burdens.
Samsun Tütünlerinin Genetik, Verim ve Kalite Varyasyonları Üretim Alanlarında Hala Devam Ediyor
Authors: KURT Dursun , SAYGILI İbrahim , KINAY Ahmet 
Published: December 2023

Amaç: Samsun bölgesi kalite tipi tütünlerin üretimi yerel çeşit, hat ya da ekotiplerle yapılmaktadır. Bu genotipler verim ve kalite bakımından önemli varyasyonlar içermektedir. Bu araştırmanın amacı bölgedeki tütün üretiminde kullanılan genotiplerindeki varyasyonun belirlenmesidir.
Materyal ve Yöntem: Samsun bölgesi tütün üretim alanlarından toplanan 28 tütün hattındaki genetik varyasyon sekiz SSR markörü ile incelenmiştir. Bu hatlar ile Bafra ve Canik 190/5 standart çeşitlerinin 2018-2019 yıllarında tütün tarımının yaygın yapıldığı Samsun-Bafra’da tarla denemelerinde verim ve kalite performansları belirlenmiştir.
Bulgular: SSR markör verileri genetik olarak 19 farklı hattı ortaya çıkarmıştır. Hatların %67’sinin en az bir allel bakımından farklılık belirlenmesi Samsun tütünlerinde varyasyonların yüksek olduğunu göstermektedir. Hatların kuru yaprak verimleri 1266-2199 kg ha-1, randımanı %43-70, brüt geliri 3474-6802 $ ha-1 arasında değişiklik göstermiştir. Hatların nikotin oranının %0.76-1.16, indirgen şeker oranının %6.7-14.2 ve fenolik bileşiklerin 44.8-938.7 ppm arasında olduğu belirlenmiştir. Hatlardan S4, S5 ve S9’un Samsun bölgesinde yaygın kullanılan standart hatlardan daha yüksek yaprak verimine sahip olduğu tespit edilmiştir. Tüm karakterler bakımından verim ve kimyasal karakterler içerisinde indirgen şeker oranında geniş bir varyasyon saptanmıştır.
Sonuç: Kaliteli Samsun tütünlerinin sürdürülebilirliği için verimi ve iyi kalite göstergelerinden dolayı özellikle S4, S5 ve S14 hatları sonraki tarla denemeleri için seçilmiştir. Bu hatların üretimde kullanımı ile tütün ürünlerinin homojenliğini ve gelir artışın sağlanacağı öngörülmektedir.
Determination of Tolerance to Drought Stress of Two American Grapevine Rootstocks by PEG Application
Authors: İLHAN Mert , BİLİR EKBİÇ Hatice 
Published: December 2023

Objective: This study was conducted to establish the in vivo protocol for the use of polyethylene glycol (PEG-6000) in 5BB (V. berlandieri x V. riparia) and 1103P (V. berlandieri x V. rupestris) American grapevine rootstocks, as well as to determine the plants' resilience to artificially induced drought stress.
Materials and Methods: The experimental design of this study was planned as a randomized complete plot design with 3 replications, each consisting of 10 plants. Polyethylene glycol (PEG-6000) was administered to the plants in each irrigation at doses of 0%, 2%, 4%, 8%, and 16%, based on the percentage of irrigation water. The application lasted for a total of 3 weeks. The study investigated the responses of plants to drought in terms of shoot development parameters (shoot fresh weight, shoot dry weight, shoot length, node and leaf number, leaf area, shoot tolerance ratio), root development parameters (root fresh weight, root number, rooting rate, root tolerance ratio, root length), and physiological development parameters (plant vitality, damage degree, leaf turgor weight, chlorophyll content, ion flux, and cell membrane damage rate).
Results: When examining the findings of the study, it was observed that polyethylene glycol material retained water, reducing the plant's water uptake and consequently creating artificial drought stress. The impact of drought induced by polyethylene glycol revealed that the 1103P rootstock exhibited higher resilience in shoot development parameters compared to the 5BB rootstock. On the contrary, the 5BB rootstock outperformed the 1103P rootstock in root development parameters. Concerning physiological development parameters, the severity of drought led to a significant decrease in plant vitality, chlorophyll content, and leaf turgor weight, while ion flux, cell membrane damage rate, and damage degree increased significantly to critical levels.
Conclusion: As a result of the research, the 1103P rootstock was found to be more successful in terms of shoot and physiological development under drought conditions, while the 5BB rootstock was found to be more successful in terms of root development parameters. Compared to other cultivation environments (in vitro, hydroponics), it was determined that polyethylene glycol (PEG) had a less pronounced effect at lower doses due to the difficulty of binding PEG in the soil. However, when compared to control plants, statistically significant differences were observed in the examined traits. Regarding the parameters investigated in this study, the 16% PEG concentration used was identified as the most effective dose in triggering drought stress.
Effect of Sleep Deprivation on the Number of Prefrontal Cortex Neuroglia Cells in Male White Rats (<i>Rattus norvegicus</i>)
Authors: Arjadi Fitranto , Kuncoro Prasetyo Tri , Gumilas Nur Signa Aini , Harini Ika Murti , Mustofa Mustofa , Wisesa Sindhu 
Published: December 2023

Stress induced by sleep deprivation can increase inflammation and oxidative stress, destroying the pyramidal and neuroglia cells in the prefrontal cerebral cortex and interrupting cognitive and behavioral functions. This study aims to observe the difference in the number of pyramidal and neuroglia cells in the prefrontal cortex of male white rats (Rattus norvegicus) after stress induction by paradoxical sleep deprivation (PSD) and total sleep deprivation (TSD). This study was conducted in the Anatomy Laboratory of the Faculty of Medicine, Universitas Jenderal Soedirman, from November 2019 to February 2020. The method of this study was a posttest-only design with a control group approach using ten rats for each group; that was control (K.I.), PSD (KII), and TSD (K.I.). PSD and TSD groups received sleep deprivation treatment for eight days for 20 hours/day and 24 hours/day, respectively. The mean pyramidal cell number decreased in the PSD (66.67±24.55) and TSD (65.90±34.91) compared to the control (77.10±26.11) group, but no significant differences were found between all groups (p>0.05). The mean neuroglial cell number was lower in the PSD (97.78±28.17) and TSD (75.80±22.39) compared to the control (126.00±48.81). Post-hoc Bonferroni test showed a significant difference between control and TSD (p<0.05) but not between control and PSD or PSD and TSD (p>0.05). In conclusion, there was a significant difference in the number of neuroglial cells but not pyramidal cells in the prefrontal cortex of male white rats (Rattus norvegicus) after stress induction with total sleep deprivation (TSD).
Exploring Variability in Sea Level at a Tide Gauge Station through Control Charts
Authors: İz H. Bâki 
Published: December 2023

Monitoring temporal changes in sea level is important in assessing coastal risk. Sea level anomalies at a tide gauge station, if kinematically conceived, include systematic variations such as trend, acceleration, periodic oscillations, and random disturbances. Among them, the non-stationary nature of the random sea level variations of known or unknown origin at coastal regions has been long recognized by the sea level community. This study proposes the analyses of subgroups of random residual statistics of a rigorously formulated kinematic model solution of tide gauge variations using X-bar and S control charts. The approach is demonstrated using Key West, Florida tide gauge records. The mean and standard errors of 5-year-long subgroups of the residuals revealed that sea level changes at this location have been progressively intensifying from 1913 to the present. Increasing oscillations in sea level at this locality may be attributed partly to the thermal expansion of seawater with increasing temperatures causing larger buoyancy-related sea level fluctuations as well as the intensification of atmospheric events including wind patterns and the impact of changes in inverted barometer effects that will alter coastal risk assessments for the future.
“God Is One” or “the One Is God” in Hellenistic Jewish and Greco-Roman Theology
Authors: Grossberg David Michael 
Published: December 2023

Abstract
“God is one” is the theological foundation of many of the world’s religions. The Greek version of this expression, heis theos, was especially significant to ancient religious development. Past scholarship has tended to place its emergence early, among the sixth century BCE Presocratic philosophers. In this article, I argue that the expression “God is one” in Greek likely develops later, in Jewish writings of the Hellenistic period. My work supports a minority opinion in the scholarship that attributions in second century Christian apologetics of this expression to Presocratics such as Xenophanes should not be relied upon. Rather, I suggest that the expression heis theos emerged in the context of second to first century BCE Alexandrian Jewish theology in conversation with ideas from Greek philosophy.
Pension System for the Rural Areas in Actual Social and Economic Conditions in China
Authors: Lebedintseva Liubov 
Published: December 2023

The article first describes and analyzes China&apos;s social support measures for rural population from 1950s to nowadays. It depicts the indistinct stages of pension system institutionalization from the time it appeared and up to the present. The major Chinese society peculiarity lies in a huge gap between standards of living in the city and in the country. It has its present characteristics due to the historical environment of official employment in Chinese villages and the previous absence of social and pension governmental support as its circumstances. In the study latent periods of switching from one pension form to the others are revealed. The fact is that China&apos;s social support measures for rural population has only history of one hundred years. However different pension forms replace each other dramatically during this time while special aspects of moral issues, family relations and social structures of Chinese society complicate the situation. Various aspects of rural pension policy in China are underexplored for that moment. The paper fills this important gap and gives much attention to its social, cultural and economical aspects. Evolution of Chinese rural pension policy starts from the &quot;Five Guarantees&quot; system, continues with the &quot;Baoji model&quot; and concludes with the &quot;New Pension System&quot; development. This system is to equalize rural and urban pension rights in China. In conclusion due to the National Social Policy only from 2014 every Chinese rural citizen aged 60 and older has pension entitlements. This fact can indicate that the primary maturity of China’s state pension system for old-age rural population has been reached.