bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review in Polymers for Fluid Loss Control in Drilling Operations
Authors: Li Ao , Gao Shangdong , Zhang Guiqing , Zeng Yinan , Hu Yangyang , Zhai Runsha , Dong Anjie , Zhang Jianhua 
Published: January 2024

AbstractThe ever‐increasing consumption of fossil energy highlights the urgent need to develop technologies to ensure the efficient drilling and exploration of oil and gas resources mainly distributed in deep layers. The complex geological conditions in deep formations with the feature of high temperature, high pressure, and high salinity result in high requirements for the performance of drilling fluids. Various additives are demonstrated to decide the physicochemical properties and functional characteristics of water‐based drilling fluids. As one of the most widely used additives in water‐based drilling fluids, various polymeric filtrate reducers play an important role in minimizing fluid loss, maintaining wellbore stability, ensuring drilling safety and efficiency as well as avoiding formation damage. Herein the design, preparation, and applications of polymer‐based filtrate reducers for fluid loss control in drilling operation are comprehensively summarized. The spotlight is centered on the design strategies and structure–property–performance relationships of polymeric filtrate reducers to minimize fluid loss under high temperature, high pressure, and high salinity conditions. Future perspectives for achieving excellent comprehensive performance are also discussed to motivate new strategies and technologies to design and develop high‐performance drilling fluids with optimal rheological and filtration properties.
Polyacetylene‐Based Asymmetric Bicyclic Polymer by Blocking‐Cyclization Technique
Authors: Ma Cuihong , Wang Hao , Sun Ruyi , Liao Xiaojuan , Han Huijing , Xie Meiran 
Published: January 2024

AbstractA rare asymmetric bicyclic polymer containing different length of conjugated polyacetylene segments is synthesized by metathesis cyclopolymerization‐mediated blocking‐cyclization technique. The size of each single ring differs from each other, and the unique cyclic polymer topology is controlled by adjusting the feed ratio of monofunctional monomer to catalyst. The topological difference between linear and bicyclic polymers is confirmed by several techniques, and the visualized morphology of asymmetric bicyclic polymer is directly observed without tedious post‐modification process. The photoelectric and thermal properties of polymers are investigated. This work expands the pathway for the derivation of cyclic polymers, and such unique topological structure enriches the diversity of cyclic polymer classes.
Investigation of product quality and advertising: Government intervention in advertising
Authors: Park Soohoon , Lee Pyoungsoo , Yoo Seung Ho 
Published: January 2024

AbstractWe investigate the joint operations and marketing decisions of a manufacturer under government intervention in advertising. We introduce four possible intervention scenarios: no government intervention, proactive intervention to maximize social welfare, proactive intervention to protect consumer rights, and reactive intervention by imposing penalties. We obtain the firm's best joint decision on product quality and advertising in response to the government's intervention. The investigation results reveal that there is no one‐size‐fits‐all strategy. The goal of consumer protection can damage the total welfare of society, while the pursuit of social welfare harms consumer rights. The government needs to carefully consider not only the characteristics of products and consumer markets to determine how it intervenes but also the effect of its policies on overall performance. It is recommended to control misleading advertising by imposing penalties reactively. By imposing penalties differently, consumer rights can be protected, while enhancing the total welfare of society. The investigation results also have important implications for business managers. There is a best mix of operations and marketing decisions that properly responds to each government policy and achieves the best profit performance.
The role of Toll‐like receptors in neuropsychiatric disorders: Immunopathology, treatment, and management
Authors: Saleki Kiarash , Alijanizadeh Parsa , Javanmehr Nima , Rezaei Nima 
Published: January 2024

AbstractNeuropsychiatric disorders denote a broad range of illnesses involving neurology and psychiatry. These disorders include depressive disorders, anxiety, schizophrenia, bipolar disorder, attention deficit hyperactivity disorder, autism spectrum disorders, headaches, and epilepsy. In addition to their main neuropathology that lies in the central nervous system (CNS), lately, studies have highlighted the role of immunity and neuroinflammation in neuropsychiatric disorders. Toll‐like receptors (TLRs) are innate receptors that act as a bridge between the innate and adaptive immune systems via adaptor proteins (e.g., MYD88) and downstream elements; TLRs are classified into 13 families that are involved in normal function and illnesses of the CNS. TLRs expression affects the course of neuropsychiatric disorders, and is influenced during their pharmacotherapy; For example, the expression of multiple TLRs is normalized during the major depressive disorder pharmacotherapy. Here, the role of TLRs in neuroimmunology, treatment, and management of neuropsychiatric disorders is discussed. We recommend longitudinal studies to comparatively assess the cell‐type‐specific expression of TLRs during treatment, illness progression, and remission. Also, further research should explore molecular insights into TLRs regulation and related pathways.
Influence of a Surgical Mask on Voice Analysis in Dysphonic Patients During the COVID‐19 Pandemic
Authors: Mehta Rupal , Mat Quentin , Maniaci Antonino , Lelubre Christophe , Duterme Jean‐Pierre 
Published: January 2024

AbstractObjectiveCOVID‐19 has radically changed medical practice. The main objective of this study was to assess the impact of surgical mask (SM) on voice quality analyzes in a group of patient with different common benign vocal organic pathologies.Study DesignA cross‐over study.SettingA group of 20 patients with different organic benign vocal pathologies was recruited from the ENT consultation of the University Hospital of Charleroi in Belgium.MethodsOn the day of the assessment, each subject underwent an endonasal laryngeal videostroboscopy followed by a voice analysis (VA) with and without a new SM. The following parameters were analyzed: fundamental frequency, maximum frequency, range in amplitude and frequency of the voice, jitter and maximum phonatory time.ResultsIn this research, we showed that VA can be performed with an SM while not changing the measured vocal parameters. These results also suggest that for the same individual a VA performed before the pandemic without SM could be compared to one with a SM to follow the patient's evolution of his or her voice quality.ConclusionThe wearing of an SM during VA should always be recommended in case of immunodeficiency, a contagious disease of the patient or during a (new) pandemic.
Prediction and adjustment of elastic properties in three‐dimensional orthogonal woven composites through dual‐scale modeling
Authors: Jing Kunkun , Zhou Hui , Wang Hao , Yan Hongyu , Xie Suchao 
Published: January 2024

AbstractThree‐dimensional (3D) orthogonal woven composites can overcome the drawback of weak interlaminar strengths in traditional laminated composites and exhibit excellent resistance to out‐of‐plane impact, however, the significant difference in properties in the in‐plane orthogonal direction will limit the potential range of application thereof. Predicting elastic properties and exploring methods of adjustment are therefore of paramount importance. Using computed tomography (CT) scanning to obtain detailed parameter models, a corresponding dual‐scale model of microscopic representative volume element (RVE) and mesoscopic RVE was established, and the accuracy of the model was experimentally validated, which can predict the elastic properties of materials. In addition, the influences of the yarn fiber volume fraction and weaving distance on elastic properties were evaluated using the elastic modulus visualization method, and a formula integrating these two factors is provided for adjustment of the in‐plane orthogonal Young's modulus.Highlights
Experimentally validated microscale and mesoscale RVE models were established.
The influences of factors on elastic properties were visualized.
The relationship between Young's modulus and influencing factors was derived.
A reliable strategy for adjusting the in‐plane Young's modulus was proposed.
Surface saturation current densities of perovskite thin films from Suns‐photoluminescence quantum yield measurements
Authors: Chin Robert Lee , Soufiani Arman Mahboubi , Fassl Paul , Zheng Jianghui , Choi Eunyoung , Ho‐Baillie Anita , Paetzold Ulrich W. , Trupke Thorsten , Hameiri Ziv 
Published: January 2024

AbstractWe present a simple yet powerful analysis of Suns‐photoluminescence quantum yield measurements that can be used to determine the surface saturation current densities of thin film semiconductors. We apply the method to state‐of‐the‐art polycrystalline perovskite thin films of varying absorber thickness. We show that the non‐radiative bimolecular recombination in these samples originates from the surfaces. To the best of our knowledge, this is the first study to demonstrate and quantify non‐linear (bimolecular) surface recombination in perovskite thin films.
Pharmacokinetic study of osilodrostat and identification of mono‐hydroxylated metabolite in equine plasma for the purpose of doping control
Authors: Ishii Hideaki , Ishikawa Yuhiro , Mizobe Fumiaki , Nomura Motoi , Yamanaka Takashi , Tanabe Sohei , Nagata Shun‐ichi , Yamada Masayuki , Leung Gary Ngai‐Wa 
Published: January 2024

RationaleOsilodrostat is an inhibitor of 11‐beta‐hydroxylase (CYP11B) and is used for the treatment of Cushing's disease but also categorized as an anabolic agent. The use of osilodrostat is prohibited in horseracing and equestrian sports. To the best of our knowledge, this is the first metabolic study of osilodrostat in equine plasma.MethodsPotential metabolites of osilodrostat were identified by differential analysis using data acquired from pre‐ and post‐administration plasma samples after protein precipitation with liquid chromatography electrospray ionization high‐resolution mass spectrometry (LC/ESI–HRMS). [Correction added on 27 January 2023, after first online publication: In the preceding sentence, “C–HRMS” was changed to “LC/ESI–HRMS” in this version.] For quantification of osilodrostat, a strong cation exchange solid‐phase extraction was employed, and the extracts were analyzed using LC/ESI–triple quadrupole tandem mass spectrometry (LC/ESI–QqQ‐MS/MS) to establish its elimination profile. Such extracts were further analyzed using LC/ESI–HRMS to investigate the detectability of osilodrostat and its identified mono‐hydroxylated metabolite over a 2‐week sampling period.ResultsMono‐hydroxylated osilodrostat was identified based on the differential analysis and mass spectrometric interpretations, and it was found to be the most abundant metabolite in plasma. Elimination profile of osilodrostat in plasma was successfully established over the 24‐h post‐administration period. Both osilodrostat and its mono‐hydroxylated metabolite were detected up to the last sampling point at 2 weeks using HRMS, and osilodrostat could be confirmed up to 8‐day post‐administration with its reference material using HRMS as well.ConclusionsFor doping control, screening of both the parent drug osilodrostat and its mono‐hydroxylated metabolite in equine plasma would be recommended due to their extended detection windows of up to 2 weeks. Given the availability of reference material for potential confirmation in forensic samples, osilodrostat is considered the most appropriate monitoring target.
Apremilast is a Potentially Useful Treatment for Severe Palmoplantar Pustulosis with Extra-Palmoplantar Symptoms
Authors: Fukushima-Nomura Ayano , Takamiyagi Saeko , Kakuta Risa , Ito Yoshihiro , Hirai Ikuko , Umemoto Junichi , Hanaoka Hironari , Kaneko Yuko , Tanese Keiji 
Published: January 2024

Abstract
Palmoplantar pustulosis (PPP) is a chronic inflammatory skin disorder affecting the palms and soles. In rare cases, severe patients develop acute extra-palmoplantar lesions often accompanied by arthralgia. Such cases with extensive symptoms often necessitate systemic treatments with variable efficacy and potential side effects. Apremilast, known for its broad immune response modulation, presents promise as a therapeutic option for severe PPP with joint and extra-palmoplantar lesions. This case highlights apremilast as a potential systemic treatment for such cases with minimal side effects.
A Case of Dupilumab-Induced Psoriasis-Like Eruption Treated with Baricitinib
Authors: Kinoshita Yuki , Imanishi Hisayoshi , Oshimo Tomoko , Tsuruta Daisuke 
Published: January 2024

Abstract
Dupilumab is a humanized monoclonal antibody against the interleukin (IL)-4 receptor alpha chain that inhibits IL-4 and IL-13 signalling. It is one of the systemic treatments for patients with moderate-to-severe atopic dermatitis (AD), which provides favourable safety and efficacy. We report a case of psoriasis-like eruption induced by dupilumab as an adverse effect in a patient with AD, immediately remitted after switching to baricitinib, which inhibits JAK1/2. Moreover, the atopic skin lesion also simultaneously went into remission upon baricitinib treatment. Baricitinib could be a favourable option for patients with AD who develop dupilumab-induced psoriasis-like eruption.
Composition‐Dependent NiS‐Enriched FeNi2S4/ZnCr2O4 Catalyst for Electrochemical Oxygen Evolution Reaction
Authors: Begum Nazrana , Biswas Rathindranath , Roy Ayan , Ahmed Imtiaz , Thakur Pooja , Haldar Krishna Kanta 
Published: January 2024

AbstractTransition metal sulfide and oxide nanomaterials are gaining popularity as catalysts for electrochemical water splitting because of their cost effectiveness, durability, and stability without using noble metals. Our study focuses on a hybrid electrocatalyst, NiS‐enriched FeNi2S4/ZnCr2O4, which is synthesized in two steps by sol‐gel followed through thermal decomposition in an aqueous solution by a hydrothermal process. We investigated its potential application in the electrochemical oxygen evolution reaction (OER). Powder X‐ray diffraction and X‐ray photoelectron spectroscopy analyses were used to determine the chemical composition and structure. The results showed that the FeNi2S4 structure has an enriched NiS phase. Additionally, the morphology of the synthesized FeNi2S4/ZnCr2O4 was revealed by field emission scanning electron microscopy (FE‐SEM). Under alkaline (1 M KOH) conditions, the FeNi2S4/ZnCr2O4 hybrid nanostructure showed a low overpotential value of 295 mV (Tafel slope, 59 mV dec−1) for OER activities due to the synergistic effects of FeNi2S4 and ZnCr2O4. Furthermore, the hybrid nanostructure demonstrated its long‐term stability and efficiency as an electrocatalyst for OER activities, surpassing previously reported superior electrocatalysts and state‐of‐the‐art materials.
Chemoselectivity Inversion of Responsive Metal–Organic Frameworks by Particle Size Tuning in the Micrometer Regime
Authors: Abylgazina Leila , Senkovska Irena , Engemann Richard , Bönisch Nadine , Gorelik Tatiana E. , Bachetzky Christopher , Kaiser Ute , Brunner Eike , Kaskel Stefan 
Published: January 2024

AbstractGated adsorption is one of the unique physical properties of flexible metal–organic frameworks with high application potential in selective adsorption and sensing of molecules. Despite recent studies that have provided some guidelines in understanding and designing structural flexibility for controlling gate opening by chemical modification of the secondary building units, currently, there is no established strategy to design a flexible MOF showing selective gated adsorption for a specific guest molecule. In a present contribution it is demonstrated for the first time, that the selectivity in the gate opening of a particular compound can be tuned, changed, and even reversed using particle size engineering DUT‐8(Zn) ([Zn2(2,6‐ndc)2(dabco)]n, 2,6‐ndc = 2,6‐naphthalenedicarboxylate, dabco = 1,4‐diazabicyclo‐[2.2.2]‐octane, DUT = Dresden University of Technology) experiences phase transition from open (op) to closed (cp) pore phase upon removal of solvent from the pores. Microcrystals show selective reopening in the presence of dichloromethane (DCM) over alcohols. Crystal downsizing to micron size unexpectedly reverses the gate opening selectivity, causing DUT‐8(Zn) to open its nanosized pores for alcohols but suppressing the responsivity toward DCM.
Kinetics Conditioning of (Electro) Chemically Stable Zn Anode with pH Regulation Toward Long‐Life Zn‐Storage Devices
Authors: Guo Yalan , Li Zhengang , Niu Ben , Chen Heng , Qiao Yu , Min Yulin , Wang Xin 
Published: January 2024

AbstractThe safety, low cost, and high power density of aqueous Zn‐based devices (AZDs) appeal to large‐scale energy storage. Yet, the presence of hydrogen evolution reaction (HER) and chemical corrosion in the AZDs leads to local OH− concentration increasement and the formation of ZnxSOy(OH)z•nH2O (ZHS) by‐products at the Zn/electrolyte interface, causing instability and irreversibility of the Zn‐anodes. Here, a strategy is proposed to regulate OH− by introducing a bio‐sourced/renewable polypeptide (ɛ‐PL) as a pH regulator in electrolyte. The consumption of OH− species is evaluated through in vitro titration and cell in vivo in situ attenuated total reflection surface‐enhanced infrared absorption spectroscopy at a macroscopic and molecular level. The introduction of ɛ‐PL is found to significantly suppress the formation of ZHS and associated side reactions, and reduce the local coordinated H2O of the Zn2+ solvation shell, widening electrochemical stable window and suppressing OH− generation during HER. As a result, the inclusion of ɛ‐PL improves the cycle time of Zn/Zn symmetrical cells from 15 to 225 h and enhances the cycle time of aqueous Zn‐ I2 cells to 1650 h compared to those with pristine electrolytes. This work highlights the potential of kinetical OH− regulation for by‐product and dendrite‐free AZDs.
Supramolecular/Dynamic Covalent Design of High‐Performance Pressure‐Sensitive Adhesive from Natural Low‐Molecular‐Weight Compounds
Authors: Luo Sha , Wang Na , Pan Yanjuan , Zheng Bo , Li Fenfang , Dong Shengyi 
Published: January 2024

AbstractAdhesive materials have played an essential role in the history of humanity. Natural adhesives composed of low‐molecular‐weight monomers have been overshadowed by modern petroleum‐based glues. With the development of green economy, the demand for eco‐friendly materials has increased. Herein, two natural biocompatible compounds, namely thioctic acid (TA) and malic acid (MA), are selected to prepare a high‐performance pressure‐sensitive adhesive poly[TA‐MA]. This adhesive can be quantitatively obtained via a simple mixing and heating process. Poly[TA‐MA] shows interesting and useful properties, including reversible flexibility, high elongation, and good self‐healing, owing to its dynamic polymerization pattern and reversible cross‐linking behavior. Poly[TA‐MA] exhibits excellent adhesion performance under various extreme conditions, such as at low temperatures and in hot water. High values of shear strength (3.86 MPa), peel strength (7.90 N cm−1), loop tack (10.60 N cm−1), tensile strength (1.02 MPa), and shear resistance (1628 h) demonstrate the strong adhesive effect of poly[TA‐MA]. Additionally, TA can be regenerated in the monomer forms from poly[TA‐MA] with high recovery rate (>90%). Meanwhile, strong anti‐bacterial behavior of poly[TA‐MA] is recorded. This study not only reported a new pressure‐sensitive adhesive but also fully displayed the feasibility of using natural small molecules to achieve robust surface adhesion.
A Distinctive Insight into Inorganic Sonosensitizers: Design Principles and Application Domains
Authors: Qin Wen , Yang Qiaoling , Zhu Chunyan , Jiao Rong , Lin Xia , Fang Chao , Guo Jiaming , Zhang Kun 
Published: January 2024

AbstractSonodynamic therapy (SDT) as a promising non‐invasive anti‐tumor means features the preferable penetration depth, which nevertheless, usually can't work without sonosensitizers. Sonosensitizers produce reactive oxygen species (ROS) in the presence of ultrasound to directly kill tumor cells, and concurrently activate anti‐tumor immunity especially after integration with tumor microenvironment (TME)‐engineered nanobiotechnologies and combined therapy. Current sonosensitizers are classified into organic and inorganic ones, and current most reviews only cover organic sonosensitizers and highlighted their anti‐tumor applications. However, there have few specific reviews that focus on inorganic sonosensitizers including their design principles, microenvironment regulation, etc. In this review, inorganic sonosensitizers are first classified according to their design rationales rather than composition, and the action rationales and underlying chemistry features are highlighted. Afterward, what and how TME is regulated based on the inorganic sonosensitizers‐based SDT nanoplatform with an emphasis on the TME targets‐engineered nanobiotechnologies are elucidated. Additionally, the combined therapy and their applications in non‐cancer diseases are also outlined. Finally, the setbacks and challenges, and proposed the potential solutions and future directions is pointed out. This review provides a comprehensive and detailed horizon on inorganic sonosensitizers, and will arouse more attentions on SDT.
Model‐based digital twins of medicine dispensers for healthcare IoT applications
Authors: Sartaj Hassan , Ali Shaukat , Yue Tao , Moberg Kjetil 
Published: January 2024

SummaryHealthcare applications with the Internet of Things (IoT) are often safety‐critical, thus, require extensive testing. Such applications are often connected to smart medical devices from various vendors. System‐level testing of such applications requires test infrastructures physically integrating medical devices, which is time and monetary‐wise expensive. Moreover, applications continuously evolve, for example, introducing new devices and users and updating software. Nevertheless, a test infrastructure enabling testing with a few devices is insufficient for testing healthcare IoT systems, hence compromising their dependability. In this paper, we propose a model‐based approach for the creation and operation of digital twins (DTs) of medicine dispensers as a replacement for physical devices to support the automated testing of IoT applications at scale. We evaluate our approach with an industrial IoT system with medicine dispensers in the context of Oslo City and its industrial partners, providing healthcare services to its residents. We study the fidelity of DTs in terms of their functional similarities with their physical counterparts: medicine dispensers. Results show that the DTs behave more than 92% similar to the physical medicine dispensers, providing a faithful replacement for the dispenser.