bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bruxism - a common problem in the adult population
Authors: Markowiak Szymon , Wardęszkiewicz Marta , Jabłońska Wiktoria , Kasprzak Amelia , Świercz Maciej , Truchta Monika , Mańkowska Aleksandra , Kolano Agata , Pejas Anna 
Published: January 2024

Introduction and Purpose:
Bruxism, the involuntary grinding or clenching of teeth, is a common problem in the adult population. This research aims to provide an overview of bruxism, focusing on its etiology, symptoms, diagnosis, and treatment, with the ultimate goal of enhancing understanding and promoting effective management strategies.

Description of the State of Knowledge:
Bruxism has been recognized as a prevalent dental disorder affecting a significant portion of the adult population. The condition involves the repetitive motion of grinding or clenching teeth, often occurring during sleep or subconsciously during waking hours. While its exact etiology remains multifactorial, stress, anxiety, malocclusion, and lifestyle factors are frequently implicated. The symptoms range from dental damage and jaw pain to headaches and disturbed sleep patterns, necessitating a comprehensive understanding of the disorder for accurate diagnosis and appropriate intervention. Current knowledge highlights the importance of early detection and tailored therapeutic approaches to alleviate symptoms and prevent complications.

Summary:
This article synthesizes existing knowledge on bruxism, addressing its etiological factors, clinical manifestations, diagnostic modalities, and available treatment options. By consolidating the state of knowledge, this research contributes to a more comprehensive understanding of bruxism and facilitates the development of evidence-based approaches for its management.
Multidisciplinary working in a community HIV specialist service
Authors: Parker-Donne Kizzy 
Published: January 2024

Objective: A documentation audit was performed to explore the multidisciplinary working of a community HIV specialist service (CHSS). The audit identified the wide range of services to which people living with HIV are referred as part of the care they receive within the CHSS. Design: A retrospective documentation audit was used. Setting: The CHSS, consisting of three teams covering a wide geographical area across West Sussex and Brighton and Hove. A total of 30 patients' notes were audited, including 10 patients from each team to ensure the results were representative of the service as a whole. Results: The audit showed that, on average, each person received five onward referrals to other health care, social care, or HIV-specific services, with a range of between 1 and 12, as a result of being under the care of the CHSS. The types of referrals varied, with 46% being to HIV specialist services and the remaining 54% to non-HIV specific services, including GPs, social services and other health services. Overall, the audit showed not only the holistic care and assessments completed but also the benefit and increased access to other services and care as a result of community HIV team involvement. Conclusion: The audit highlights the importance of continuing to develop HIV community services to cater for this changing population, as well as identifying possible areas of development. The results also demonstrate the vital role that CHSSs have in supporting hard-to-reach patients.
Chemical compositions, antioxidant and antibacterial activities of kepel (Stelechocarpus burahol) fruit flesh and peel extracts
Authors: SUNDARI DEWI , HANDAYANI DESI SUCI , SURYANTI VENTY 
Published: January 2024

Abstract. Sundari D, Handayani DS, Suryanti V. 2023. Chemical compositions, antioxidant and antibacterial activities of kepel (Stelechocarpus burahol) fruit flesh and peel extracts. Biodiversitas 24: 4668-4675. Kepel (Stelechocarpus burahol (Bl.) Hook f. & Th.) has been utilized by royalty in Java, Indonesia as perfume, deodorant and anti-agingagent. S. burahol fruit flesh has diuretic properties and can helpavoid kidney irritation. S. buraholpossesses anti-hyperuricemia and xanthine oxidase inhibitory properties, as well as antiseptic, anti-inflammatory, and antioxidant activity. Chemical contents and biological activities of S. burahol fruit and peel extracts were investigated in the present study. Based on GC-MS spectra, methanol fruits extract contains dodecanoic acid-1,2,3-propanetriyl ester. Methanol peel extract contains hexadecanoic acid methyl ester; 2,6,10,15,19,23-hexamethyl-2,6,10,14,18,22-tetracosahexaene and dodecanoic acid-1,2,3-propanetriyl ester. Ethyl acetate peel extract contains dodecanoic acid-1,2,3-propanetriyl ester. LC-MS analysis revealed that ethyl acetate fruit flesh extract contains pelargonidin-malonylrhamnoside (anthocyanins), 8-epiiridodial glucoside tetraacetate (isoprenoid), epigallocatechin gallate (catechin) and 5-octadecenal (fatty aldehydes). Ethyl acetate fruit peel extract contains 1,5-dicaffeoylquinic acid (flavonoid), 1,6-di-o-galloylglucose (tannins), luteolin 7-O-glucoside (cynaroside),methyl hemiacetal in 3,4-DHPEA-EA (iridoids). Methanol extract of fruit flesh has strong antioxidant activity, whereas three other extracts have very strong antioxidant activities. S. burahol peel extract inhibited the S. aureus growth at a concentration extract of 15,000 to 25,000 ppm. These antioxidant and antibacterial activities are associated with the chemical composition of S. burahol fruit flesh and peel extracts. Further research into other biological functions and in vivo investigations are required for future studies.
The potential of invasive species Praxelis clematidea extract as a bioherbicide for Asystasia gangetica
Authors: WARDINI TRIMURTI HESTI , AFIFA INAS NUHA , ESYANTI RIZKITA RACHMI , ASTUTININGSIH NOVI TRI , PUJISISWANTO HIDAYAT 
Published: January 2024

Abstract. Wardini TH, Afifa IN, Esyanti RR, Astutiningsih NT, Pujisiswanto AH. 2023. The potential of invasive species Praxelis clematidea extract as a bioherbicide for Asystasia gangetica. Biodiversitas 24: 4738-4746. The occurrence of weeds in agriculture directly impacts crop productivity, and the reliance on synthetic herbicides to solve the problem has raised concerns about the increasing environmental damage. Using bioherbicides to control weeds is necessary to reduce the negative impact of synthetic herbicides. Bioactive compounds derived from plants can be utilized to develop eco-friendly herbicides. Praxelis clematidea extract was reported to exhibit allelopathic activity against weeds. This study aims to evaluate the potential of P. clematidea extract as a bioherbicide to control seed germination and seedling growth of Asystasia gangetica weed. P. clematidea water extract was screened for its chemical compounds and determined its phytotoxic effects on Asystasia gangetica. The results showed that P. clematidea water extract contained phenolics, alkaloids, and terpenoids. P. clematidea extract suppressed seed germination, the time needed for seed germination, sprout length, number of leaves, biomass, and total chlorophyll contents. LC50values for the seed germination, seedling, root, and shoot growth were calculated at 9%, 25%, 11%,and 37% (v/v), respectively. Thus, P. clematidea could be used as an A. gangetica weed biocontrol agent and might be integrated into weed management programs.
Evaluation of bioprospecting potential of epiphytic Gracilaria edulis harvested from seaweed farm in Seriwe Bay, Lombok, Indonesia
Authors: PRASEDYA EKA SUNARWIDHI , FITRIANI FITRIANI , SARASWATI PUTU BELLA APRILLIA , HAQIQI NIRWANA , QORIASMADILLAH WANDA , HIKMATURROHMI HIKMATURROHMI , NURHIDAYATI SITI ZAINIAH , ARIATI PUTU EKA PASMIDI 
Published: January 2024

Abstract. Prasedya ES, Fitriani F, Saraswati PBA, Haqiqi N, Qoriasmadillah W, Hikmaturrohmi H, Nurhidayati SZ, Ariati PEP. 2023. Evaluation of bioprospecting potential of epiphytic Gracilaria edulis harvested from seaweed farm in Seriwe Bay, Lombok, Indonesia. Biodiversitas 24: 5343-5351. The seaweed industry is strategically important in Indonesia, comprising over 40% of the nation's aquaculture annual production. Despite the industry's promising growth, various challenges and problems remain, including intense epiphyte infestation. Hence, investigating the economic value of these epiphytes could provide new opportunities for potential industrial applications. Epiphytic algae is commonly found growing on commercial seaweeds which causes decreased biomass and increased risk of crop failure. Information regarding these epiphytic algae remains limited. This study investigates the molecular identification of the abundant epiphytic macroalgae found in one of the largest seaweed farms in, Seriwe Bay, Lombok, Indonesia. In addition, the epiphytic bioactive activity is also evaluated for further industrial potential. Molecular identification with the mitochondrial marker COX1 identifies the epiphytic macroalgae as Gracilaria edulis (S.G.Gmel.) P.C.Silva. The Indonesian G. edulis is closely related to the G. edulis specimens from Malaysia (JQ026083.1), Philippines (KY995636.1 and KY995635.1), and Thailand (JQ026088.1). The outgroup used was the G. edulis specimen from India (KP099563.1) because it shows the most distinct relationship to the other specimens. Extracted agar of Seriwe G. edulis shows moderate yield (21%) and low gel strength (134 g/cm2). The phytochemical content analyses show that G. edulis agar has a TPC value of 3.65 ± 0.52 mg GAE/g and promising antioxidant activity (DPPH IC50 = 797.40 ± 1.50 µg/mL; ABTS IC50 = 558.40 ± 1.44 µg/mL). Further phytochemical profiling with GCMS shows various promising major constituents such as tetradecanoic acid, neophyte diene, pentadecanoic acid, and hexadecanoic acid. Therefore, the findings suggest that G. edulis displays potential applications in the functional food and cosmetic industry.
Species diversity of Annonaceae in the four selected protected areas in the Bicol Region, Philippines
Authors: RETUERMA-DIONEDA ANNE , ALEJANDRO GRECEBIO JONATHAN D. 
Published: January 2024

Abstract. Retuerma-Dioneda A, Alejandro GJD. 2023. Species diversity of Annonaceae in the four selected protected areas in the Bicol Region, Philippines. Biodiversitas 24: 5428-5438. An explorational survey of four selected protected areas (PAs) was conducted in the Bicol region for Annonaceae. The study aimed to provide species diversity of Annonaceae with an account of their endemicity and distribution. The four PAs were the Abasig-Matogdon-Mananap Natural Biotic Area (AMMNBA), Bulusan Volcano Natural Park (BVNP), Mt. Isarog Natural Park (MINP), and Mt. Mayon Volcano Natural Park (MMVNP). Thirty samples were collected and identified, 16 species belonging to 13 genera, namely Annona, Artabotrys, Cananga, Drepananthus, Goniothalamus, Fissistigma, Friesodielsia, Meiogyne, Monoon, Phaeanthus, Polyalthia, Popowia, and Uvaria. Miliuseae is the most species-rich tribe with 7 species (43.75%), followed by Uvarieae with 4 species (25%), Annoneae with 2 species, Canangeae with 2 species (12.5% each), and Xylopieae with 1 species (6.25%). A key of all Annonaceae species collected in the four PAs is provided here. Five Philippine endemic species were identified, namely G. elmeri in the four PAs; P. luzonensis in three PAs; F. lanceolata, and P. lanceolata in AMMNBA; and U. valderramensis in BVNP. AMMNBA has the highest number of species (43%). The species identified comprises 10.88% of the 147 recorded Philippine Annonaceae species. The results highlight the presence and occurrence of Annonaceae essential for management and conservation policy.
Glucanase activity produced by rhizospheric Streptomyces tritolerans ARJ 32 and Streptomyces collinus ARJ 38 and the analysis of their encoding genes
Authors: BUDIMAN DEMMA ZILBA , PURWANINGTYAS WIDYA ESTI , PRIYANTO JEPRI AGUNG , PUTRA IVAN PERMANA , NAWANGSIH ABDJAD ASIH , WAHYUDI ARIS TRI 
Published: January 2024

Abstract. Budiman DZ, Purwaningtyas WE, Priyanto JA, Putra IP, Nawangsih AA, Wahyudi AT. 2023. Glucanase activity produced by rhizospheric Streptomyces tritolerans ARJ 32 and Streptomyces collinus ARJ 38 and the analysis of their encoding genes. Biodiversitas 24: 5831-5837. The enzyme ?-1,3-glucanase is capable of breaking down the glucan components in the cell walls of phytopathogenic fungi. Streptomyces spp. isolated from the maize rhizosphere, are believed to produce enzymes with glucanolytic activity, making them promising candidates for use as a biological control agent against these fungi. This work aims to quantitatively analyze the enzymatic activity of glucanase in Streptomyces tritolerans ARJ 32 and Streptomyces collinus ARJ 38 and identify their encoding genes (bglS) and the three-dimensional modeling of their protein structures. The dinitrosalicylic acid (DNS) method quantitively assays the glucanase enzyme. The TA-Cloning of the bglS gene was performed using pGEM-T Easy Plasmid Vector, and the three-dimensional protein structure was constructed using the I-TASSER program. According to the findings, both Streptomyces isolates exhibited glucanolytic activity. The glucanase enzyme activities of S. tritolerans ARJ 32 and S. collinus ARJ 38 peaked at eight days of incubation, with values of 31.116 U/mg and 41.599 U/mg, respectively. The partial bglS gene was present in both Streptomyces and identified as endo-?-1,3-glucanase from the glycoside hydrolase family 16 (GH 16). The deduced partial amino acid sequences were aligned and showed some highly conserved residue in the catalytic domain of GH 16. The three-dimensional structural model built from the partial bglS amino acid sequences displayed high-quality parameters and overlapped with the protein model of partial endo-?-1,3-glucanase from Nocardiopsis sp. F96 (2HYK). These preliminary results suggest that the two Streptomyces isolates had the potential to be used as glucanase enzyme producers.
Democratic Measures for Curbing Electoral Violence in Kanyama Constituency of Lusaka District, Zambia
Authors: Kawila Eliazer Lushinga , Matole Adrian , Mulubale Sanny , Simui Francis , Muleya Gistered 
Published: January 2024

In Kanyama Constituency of Lusaka District Zambia, physical violence especially during the election cycles of 2011, 2016 and 2021 may appear to have escalated. If violence and tyranny are allowed to take root in any democratic state, it may deprive the people of the capacity to resist bad governance because of the pervasive atmosphere of terror, fear and insecurity. Based on the foregoing context, this article explored Democratic measures that can be used to curb electoral violence in Kanyama Constituency of Lusaka District, Zambia. The article employed qualitative approach with a case study design. Twenty eight (28) participants were recruited for this research and they provided Primary data. The main findings of this research were that good political culture in the electoral process, enhancing civic and voter education, fair application of the law, formation and enhancing of youth empowerment programmes, responsive leadership both at party and national levels are the key democratic measures that can be used to curb electoral violence. Equally, having independent government institutions that are mandated to conduct elections is key as their operations may not be ill influenced by external forces. The article recommends that Political parties and constituencies should treat election period as an opportunity to elect credible leaders through democratic means than a possibility to intimidate those with divergent views.
Learning to Teach by Practice: Pre-service Teachers’ Experiences of Using Poetry Memorization, Dramatization and Recitation Pedagogy
Authors: Nambi Rebecca , Busimba James Taabu , Lutaaya Josephine Najjemba , Atuhura Dorothy , Nabiryo Nancy Rosemary 
Published: January 2024

In Uganda, poetry is a key genre in the Literature in English curriculum at the secondary and higher institutions of teacher education. However, many teachers, especially the novices, struggle with the teaching of poetry in secondary schools in Uganda. Current approaches to teaching support learner-centered pedagogy where learners are facilitated to fully participate in scaffolding their own interpretations of the subject content. Individual in-class poetry recitation is one such activity used to teach, and taught to, pre-service teachers of poetry because it promotes their participation and their general attitude towards poetry. In this paper, we present findings from a study about Makerere University pre-service teachers’ experiences of using individual in-class poetry recitations as a learner-centered strategy for teaching poetry. The research was carried out amongst one cohort of finalist teacher trainees of English and Literature using lecture observation, interviews and open-ended questionnaire research methods. A thematic analysis of the data revealed three themes that summarize their experiences with memorization, recitation and dramatization of poetry: recitation: facing the class; and pedagogical reflections. As we present these themes, we also draw some pedagogical implications for poetry classes from the actual recitation experiences of teacher trainees who participated in this study.
Analoge Juris-Vorgänger – juristische Entscheidungssammlungen aus der napoleonischen Zeit
Authors: Brettschneider Peter , Patrzek Ines 
Published: January 2024

Zusammenfassung
Heute spielen sich juristische Recherchen primär in Datenbanken ab. Aber auch frühere Juristinnen und Juristen schafften Ordnungssysteme, die sie bei der Suche nach Präzedenzfällen und Urteilen unterstützten. Der Beitrag beschreibt zwei mit hohem Aufwand zusammengetragene analoge Vorläufer von Entscheidungsdatenbanken, die um die Wende zum 19. Jahrhundert zusammengestellt wurden. Nicht zuletzt enthalten diese auch ein bibliothekswissenschaftlich bemerkenswertes, frühes Beispiel für einen Schlagwortkatalog.
The pyroptosis-related signature predicts prognosis and influences the tumor immune microenvironment in dedifferentiated liposarcoma
Authors: Chen Wenjing , Cheng Jun , Cai Yiqi , Wang Pengfei , Jin Jinji 
Published: January 2024

Abstract

Background
Dedifferentiated liposarcoma (DDL), a member of malignant mesenchymal tumors, has a high local recurrence rate and poor prognosis. Pyroptosis, a newly discovered programmed cell death, is tightly connected with the progression and outcome of tumor.

Objective
The aim of this study was to explore the role of pyroptosis in DDL.

Methods
We obtained the RNA sequencing data from The Cancer Genome Atlas (TCGA) and Genotype-Tissue Expression databases to identify different pyroptosis-related genes (PRGs) expression pattern. An unsupervised method for clustering based on PRGs was performed. Based on the result of cluster analysis, we researched clinical outcomes and immune microenvironment between clusters. The differentially expressed genes (DEGs) between the two clusters were used to develop a prognosis model by the LASSO Cox regression method, followed by the performance of functional enrichment analysis and single-sample gene set enrichment analysis. All of the above results were validated in the Gene Expression Omnibus (GEO) dataset.

Results
Forty-one differentially expressed PRGs were found between tumor and normal tissues. A consensus clustering analysis based on PRGs was conducted and classified DDL patients into two clusters. Cluster 2 showed a better outcome, higher immune scores, higher immune cells abundances, and higher expression levels in numerous immune checkpoints. DEGs between clusters were identified. A total of 5 gene signatures was built based on the DEGs and divided all DDL patients of the TCGA cohort into low-risk and high-risk groups. The low-risk group indicates greater inflammatory cell infiltration and better outcome. For external validation, the survival difference and immune landscape between the two risk groups of the GEO cohort were also significant. Receiver operating characteristic curves implied that the risk model could exert its function as an outstanding predictor in predicting DDL patients’ prognoses.

Conclusion
Our findings revealed the clinical implication and key role in tumor immunity of PRGs in DDL. The risk model is a promising predictive tool that could provide a fundamental basis for future studies and individualized immunotherapy.
Порівняльна ефективність антивікового впливу наночастинок ортованадату, метформіну та калорійно обмеженої дієти при експериментальному прискореному старінні щурів
Authors: Нікітченко Ю.В. , Клочков В.К. , Кавок Н.С. , Карпенко Н.О. , Сєдих О.О. , Нікітченко І.В. , Божков А.І. , Єфімова С.Л. , Семиноженко В.П. 
Published: January 2024

Досліджено вплив ортованадатних наночастинок (ОВ НЧ — GdVO4 /Eu3+ (8×25 нм)), калорійно обмеженої дієти (КОД) та міметика КОД — метформіну (Мет) на виживаність та стан прооксидантно-антиоксидантного балансу в печінці та крові самців щурів Вістар, прискорене старіння яких моделювали надмір-ним харчуванням (НХ) у ранньому постнатальному онтогенезі. Встановлено, що виживаність щурів, які отримували НХ була меншою, ніж у контрольних тварин. При цьому виявлено, що у мітохондріях і мікросомах печінки та сироватці крові молодих щурів, які отримували НХ, швидкість генерації супероксидного радикала та вміст гідроперекисів ліпідів вища, а активність глутатіонпероксидази та вміст відновленого глутатіону істотно нижчі у порівнянні з контрольними тваринами. Довготривале застосування ОВ НЧ, КОД або Мет у щурів, які отримували НХ, нормалізувало прооксидантно-антиоксидантний баланс та значно збільшувало виживаність піддослідних тварин. При цьому ступінь виживаності була виразнішою
при застосуванні КОД та НЧ GdVO4/Eu3+. Враховуючи дані літератури про неприйнятність тривалого застосування калорійно обмеженої дієти у людей, а також неоднозначність даних літератури про геропротекторний ефект метформіну, отримані результати дозволяють зробити висновок, що на даний час для розробки засобів, які уповільнюють прискорене старіння організму, найбільш перспективним є використання наночастинок GdVO4/Eu3+ .
Комплексне дослідження стану периферичної крові первинних хворих на рак шийки матки
Authors: Дьоміна Е.А. , Главін О.А. , Маковецька Л.І. , Михайленко В.М. 
Published: January 2024

Рак шийки матки є однією з найпоширеніших патологій у структурі онкологічної захворюваності жіночого населення України. Значну роль у розвитку і прогресуванні цього захворювання відіграє окисний стрес. Внаслідок променевої терапії хворих частина нормальних клітин з оточення пухлини також зазнає опромінення, що може обумовити розвиток віддалених променевих ускладнень. У хворих до початку терапії було визначено низку біологічних показників, що відображають стан окисних процесів у периферичній крові, а також рівень пошкодження ДНК і апоптозу лімфоцитів та порівняно їх з показниками контрольної групи. Виявлено підвищення генерації супероксид-аніон-радикала у лімфоцитах в 1,8 раза, зниження вмісту сульфгідрильних груп білків у плазмі в 1,6 раза і зростання прооксидантно-антиоксидантного співвідношення крові в 1,4 раза, що свідчить про розвиток окисного стресу. У лімфоцитах ці зміни супроводжувалися падінням трансмембранного потенціалу мітохондрій в 1,8 раза та зростанням рівня двониткових розривів ДНК і апоптозу в 2,1 і 3,5 раза відповідно. Встановлено зворотну кореляцію між загальною продукцією вільнорадикальних сполук у лімфоцитах і генерацією ними супероксид-аніон-радикала, що свідчить про його важливу роль у пошкодженні цих клітин у хворих на рак шийки матки. Одержані дані будуть слугувати контролем для визначення радіаційно-індукованих змін у здорових клітинах із оточення пухлини після променевої терапії.