bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improving cardiovascular health in patients with an abdominal aortic aneurysm: development of the cardiovascular risk reduction in patients with aneurysms (CRISP) behaviour change intervention
Authors: Withers Tom M. , Greaves Colin J. , Bown Matt J. , Saratzis Athanasios 
Published: January 2024

Abstract
Background
Abdominal aortic aneurysm (AAA) is an important cardiovascular health problem. Ultrasound screening is proven to reduce AAA mortality and programmes have been implemented in some healthcare systems. Those who are identified as having a small AAA in screening enter into a surveillance programme to monitor AAA size. Individuals in AAA surveillance are at elevated risk of cardiovascular events, which is not currently addressed sufficiently. We aimed to develop a simple intervention to reduce cardiovascular risk, which could be embedded in AAA surveillance pathways.

Methods
Intervention mapping methods were used to co-develop the intervention with individuals with AAA, families/carers, and healthcare staff. We identified “targets for change” by synthesising research evidence and international guidelines and consulting with patients, caregivers and health service providers. We conducted a series of workshops to identify barriers to and facilitators of change and used taxonomies of behaviour change theories and techniques to match intervention strategies to each target. Further stakeholder involvement work helped refine the intervention.

Results
The developed intervention focusses on assessment and individually tailored discussion of risk factors, exchanging information, building motivation and action planning, followed by review of progress and problem-solving. Workbooks covering physical activity, diet, stress management, alcohol, smoking, blood pressure and mental health are provided to support behaviour change. The intervention is facilitated by trained healthcare professionals during the patient’s AAA screening appointment for the duration that they are in surveillance.

Discussion
The developed intervention will now be tested to assess whether it can be integrated with the current AAA screening programme. The developed intervention is a novel approach to reducing cardiovascular disease in the AAA population, it is also the first intervention which tries to do this in this population.

Trial registration
International Clinical Trial Registration: ISRCTN93993995.
A hybrid econometrics and machine learning based modeling of realized volatility of natural gas
Authors: Kristjanpoller Werner 
Published: January 2024

AbstractDetermining which variables affect price realized volatility has always been challenging. This paper proposes to explain how financial assets influence realized volatility by developing an optimal day-to-day forecast. The methodological proposal is based on using the best econometric and machine learning models to forecast realized volatility. In particular, the best forecasting from heterogeneous autoregressive and long short-term memory models are used to determine the influence of the Standard and Poor’s 500 index, euro–US dollar exchange rate, price of gold, and price of Brent crude oil on the realized volatility of natural gas. These financial assets influenced the realized volatility of natural gas in 87.4% of the days analyzed; the euro–US dollar exchange rate was the primary financial asset and explained 40.1% of the influence. The results of the proposed daily analysis differed from those of the methodology used to study the entire period. The traditional model, which studies the entire period, cannot determine temporal effects, whereas the proposed methodology can. The proposed methodology allows us to distinguish the effects for each day, week, or month rather than averages for entire periods, with the flexibility to analyze different frequencies and periods. This methodological capability is key to analyzing influences and making decisions about realized volatility.
Performance-based assessment in virtual versus non-virtual classes: impacts on academic resilience, motivation, teacher support, and personal best goals
Authors: Aladini Alaa , Bayat Sania , Abdellatif Mohamed Sayed 
Published: January 2024

AbstractThis study investigated the Performance-Based Assessment (PBA) impact on academic resilience (AR), motivation, teacher support (TS), and personal best goals (PBGs) in different learning environments, specifically online classes and traditional physical classrooms. The research involved 84 participants divided into experimental (online classes, N = 41), and control (physical classes, N = 43) groups. Questionnaires were administered before and after the treatment to assess the participants’ AR, motivation, TS, and PBGs. The data were analyzed using Chi-square tests, revealing significant differences in AR, motivation, and PBGs between the two groups after the treatment. Online classes were found to enhance AR, motivation, PBGs, and acknowledgment of TS compared to the physical environment. These results suggest that PBA can have a positive impact on students’ psychosocial variables and shed light on the potential benefits of online learning environments. The implications of the study are discussed, and suggestions for further research are provided.
Exploring Elinor Ostrom's principles for collaborative group working within a user-led project: lessons from a collaboration between researchers and a user-led organisation
Authors: Wheeler Bella , Williams Oli , Meakin Becki , Chambers Eleni , Beresford Peter , O’Brien Sarah , Robert Glenn 
Published: January 2024

Abstract
Background
Some research has been undertaken into the mechanisms that shape successful participatory approaches in the context of efforts to improve health and social care. However, greater attention needs to be directed to how partnerships between researchers and user-led organisations (ULOs) might best be formed, practiced, managed, and assessed. We explored whether political economist Elinor Ostrom’s Nobel prize winning analysis of common pool resource management—specifically eight principles to enhance collaborative group working as derived from her empirical research—could be usefully applied within a user-led project aiming to co-design new services to support more inclusive involvement of Disabled people in decision-making processes in policy and practice.

Methods
Participant observation and participatory methods over a 16-month period comprising observational notes of online user-led meetings (26 h), online study team meetings (20 h), online Joint Interpretive Forum meetings (8 h), and semi-structured one-to-one interviews with project participants (44 h) at two time points (months 6 and 10).

Results
Initially it proved difficult to establish working practices informed by Ostrom’s principles for collaborative group working within the user-led project. Several attempts were made to put a structure in place that met the needs of both the research study and the aims of the user-led project, but this was not straightforward. An important shift saw a move away from directly applying the principles to the working practices of the group and instead applying them to specific tasks the group were undertaking. This was a helpful realisation which enabled the principles to become—for most but not all participants—a useful facilitation device in the latter stages of the project. Eventually we applied the principles in a way that was useful and enabled collaboration between researchers and a ULO (albeit in unexpected ways).

Conclusions
Our joint reflections emphasise the importance of being reflexive and responsive when seeking to apply theories of collaboration (the principles) within user-led work. At an early stage, it is important to agree shared definitions and understanding of what ‘user-led’ means in practice. It is crucial to actively adapt and translate the principles in ways that make them more accessible and applicable within groups where prior knowledge of their origins is both unlikely and unnecessary.
The effect of macronutrient and micronutrient supplements on COVID-19: an umbrella review
Authors: SeyedAlinaghi SeyedAhmad , Shahidi Ramin , Mojdeganlou Hengameh , Akhtaran Fatemeh Khajeh , Maroufi Seyed Farzad , Maroufi Seyede Parmis , Mirzapour Pegah , Karimi Amirali , Khodaei Sepideh , Pour Mehrzad Mohsseni , Mehraeen Esmaeil , Dadras Omid 
Published: January 2024

Abstract
Background and aims
A healthy diet play an important role in the prevention and even treatment of various diseases. Proper nutrition plays an important role in boosting of immune system. These include the consumption of macronutrients such as proteins, lipids, carbohydrates, and also micronutrients including vitamins. Here, we aimed to systematically review the effects of macronutrients and micronutrients on the prevention and treatment of COVID-19.

Methods
We searched the databases of PubMed, Scopus, Embase, and Web of Science on December 23, 2023. The records were downloaded into an EndNote file, the duplicates were removed, and the studies underwent a two-phase screening process based on their title/abstracts and full texts. The included articles were screened and underwent inclusion and exclusion criteria. We included the English systematic reviews and meta-analyses that concurred with the aim of our study. The selected articles were assessed by Cochrane's Risk of Bias in Systematic Reviews for the quality check. The data of the eligible studies were extracted in a pre-designed word table and were used for the qualitative synthesis.

Results
A total of 28 reviews were included in this study. Most studies have shown that micronutrients are effective in morbidity and mortality controlling in viral respiratory infections such as COVID-19 but some studies have shown that micronutrients are sometimes not effective in controlling severity. On the other hand, calcifediol was by far the most successful agent in reducing intensive care needs and mortality between studies.

Conclusion
Individuals without malnutrition had a reduced risk of SARS-CoV-2 infection and severe disease. The administration of Vitamin D is effective in reducing the morbidity and mortality of COVID-19 patients. Patients with vitamin D deficiency were more prone to experience severe infection, and they were at higher risk of morbidities and mortality. Other micronutrients such as Vitamin A, Vitamin B, and Zinc also showed some benefits in patients with COVID-19. Vitamin C showed no efficacy in COVID-19 management even in intravenous form or in high doses.
Toxicological analyses of the venoms of Nigerian vipers Echis ocellatus and Bitis arietans
Authors: Dingwoke Emeka John , Adamude Fatima Adis , Salihu Aliyu , Abubakar Mujitaba Suleiman , Sallau Abdullahi Balarabe 
Published: January 2024

Abstract
Background
Among the medically important snakes in Nigeria, Echis ocellatus and Bitis arietans have the most lethal venom. These venoms were classified according to the presence of snake venom metalloproteinases (SVMPs), snake venom phospholipase A2 (PLA2s), and snake venom serine proteases (SVSPs). Toxicological analyzes were performed to understand the significance of different protein families in venoms.

Methods
Proteins were separated from venom using column chromatography. The skin and footpad of mice were used to determine hemorrhagic and edematogenic activities. Caprine blood plasma was used to test fibrinolytic activity in vitro.

Results
The results showed that, compared to the crude venom, the SVMP fraction induced hemorrhagic effects with a diameter of 26.00 ± 1.00 mm in E. ocellatus and 21.33 ± 1.52 mm in B. arietans. Both SVSP and SVMP had anticoagulant effects; however, the SVSP fraction had a stronger effect, with a longer anticoagulation time of 30.00 ± 3.00 min in E. ocellatus and 26.00 ± 2.00 min in B. arietans. These main venom toxins, SVMPs, SVSPs, and PLA2, were found to have edema-forming effects that were optimal at 2 h after envenomation. PLA2s had the highest edema-inducing activity, with onset 30 min after envenomation.

Conclusions
Given the importance of SVMPs in altering the integrity of the membrane structure and impairing the blood coagulation system, an antivenom that can specifically neutralize its activity could inhibit the hemorrhage effects of the venoms.
Midwest prairie management practices benefit the non-target prairie crayfish
Authors: Bloomer Caitlin C. , Miller Christopher M. , DiStefano Robert J. , Taylor Christopher A. 
Published: January 2024

Abstract
Background
Prescribed burning is used to duplicate natural, pre-settlement prairie successional processes. It is an essential and commonly used tool to promote and protect biodiversity and enhance ecosystem function in tallgrass prairie remnants throughout the midwestern United States. The responses to prescribed burns vary widely among faunal groups. We conducted the first study into the response of the prairie crayfish (Procambarus gracilis Bundy) to periodic prescribed burns and other management activities in a tallgrass prairie in Northern Missouri. This species relies on natural and restored prairies across its broad distribution, but little is known on how to actively manage these populations.

Results
We found that the density of the prairie crayfish burrows did not vary in response to the burn regime; however, other management activities like the installation of artificial ponds for amphibians and reptiles were directly benefitting this species. Observations indicate that prairie crayfish may also show positive associations with warm-season grass stands and vegetation management should be further explored.

Conclusions
The current prairie management practices for vegetation, quail, and herpetofauna are having beneficial or neutral effects on non-target taxa like the prairie crayfish. The value of crayfish and their burrows in prairies is well-established. Conservation biologists should continue to examine how burrowing crayfish are responding to management practices for other taxa to explicitly manage and promote these populations.
Multicriteria decision-making tool for investigating the feasibility of the green roof systems in Egypt
Authors: Desouki Mahmoud , Madkour Mai , Abdeen Ahmed , Elboshy Bahaa 
Published: January 2024

AbstractUrbanization in Egypt detracts from green spaces, reduces the per capita green ratio, and increases adverse effects such as heat islands, air pollution, and energy consumption. In addition, it affects social human comfort issues. In this context, building rooftops is a potential solution that could reduce the impact of green space scarcity. Such a solution has multiple evidence-based environmental, economic, and social benefits. Consequently, numerous governmental and private initiatives have spread the rooftop greening concept in Egypt. These initiatives have adopted several planting systems, such as soil-based, deep-water culture, and nutrient film technique systems. This manuscript examines these prevalent systems through environmental, economic and social lenses. This paper pioneers a user-centric tool to facilitate the system selection that aligns with individual needs. An analysis was conducted to ascertain the value of various factors influencing system choice, encompassing a literature review, expert opinion solicitation, market survey, and energy simulation. The Analytical Hierarchy Processes methodology was proposed to appraise the factors, aiding in arriving at an informed decision. The paper presents a novel contribution by studying many factors spanning diverse scientific domains. Furthermore, creating an accessible decision-support tool encapsulates a substantial addition to the body of knowledge.
Preoperative management using Impella support for acute aortic dissection with left coronary malperfusion: a case report
Authors: Shojima Takahiro , Takagi Kazuyoshi , Saku Kosuke , Fukuda Tomofumi , Tayama Eiki 
Published: January 2024

Abstract
Background
Acute aortic dissection (AAD) with impaired perfusion of the left coronary artery has a poor prognosis, even after urgent radical aortic surgery, due to extensive myocardial damage. Although Impella, a microaxial-flow catheter pump, is useful in managing acute myocardial infarction, it is generally contraindicated in patients with AAD because it is an intra-aortic device and the aortic structure is compromised in these cases. Here, we introduce a novel intervention that allowed a planned aortic repair after managing circulation using Impella and venoarterial extracorporeal membrane oxygenation in a case of AAD with left main trunk malperfusion.

Case presentation
A 40-year-old man presented with cardiogenic shock. Percutaneous coronary intervention was performed to address left main trunk obstruction using an intra-aortic balloon pump; however, circulatory instability persisted. The patient was transferred to our hospital after venoarterial extracorporeal membrane oxygenation. Impella CP™ was used to improve his circulatory status. However, a subsequent CT scan confirmed an AAD diagnosis. After 5 days of stable circulatory support, the patient underwent aortic root replacement and coronary artery bypass grafting.

Conclusions
In patients with AAD and coronary malperfusion, adjunctive circulatory management with Impella may be a valuable therapeutic option.
Three cases of diagnostic delay of type A acute aortic dissection
Authors: Shimamoto Takeshi , Tomotsuka Sanae , Takehara Makoto , Tsumaru Shinichi 
Published: January 2024

Abstract
Background
Diagnostic delay (DD) can be lethal when patients with type A acute aortic dissection (TAAAD). We report 3 cases of DD associated with TAAAD.

Case presentation
Case 1 is a female in her sixties presenting with severe back pain. A CT scan was taken, and TAAAD with a thrombosed false lumen was suspected by the radiology technician. He did not successfully transfer his concern to the physicians and the patient was sent home. The next day, she was transferred to another hospital with a recurrence of the symptom, and the diagnosis of TAAAD was made with a CT scan there. Case 2 was an 87-year-old female who was transferred to our hospital because of a loss of consciousness and bruises on the forehead. CT scan was taken and the displaced intimal flap in her aortic arch was overlooked by the part-time physician almost at the end of his shift. The diagnosis of TAAAD was made by the radiologist. Case 3 was the 44-year-old male who did not have health insurance and experienced severe back pain a few days before the visit to our clinic. On that day, he went to the nearby hospital’s emergency room, and only pain medication was prescribed. A few days later, a CT scan was taken at our hospital to investigate the cause of pyuria and the diagnosis of TAAAD was made.

Conclusion
DD may be common and multifactorial in our practice. Physicians need to take every step to improve diagnostic accuracy.
Cardiovascular biomarkers: exploring troponin and BNP applications in conditions related to carbon monoxide exposure
Authors: Taghdiri Andia 
Published: January 2024

Abstract
Background
The diagnosis and prognosis of cardiovascular disorders are greatly aided by cardiovascular biomarkers. The uses of troponin and B-type natriuretic peptide in situations involving carbon monoxide exposure are examined in this narrative review. These biomarkers are important because they help predict outcomes in cardiovascular disorders, track the effectiveness of therapy, and influence therapeutic choices.

Main body
Clinical practice makes considerable use of B-type natriuretic peptide (BNP), which has diuretic and vasodilatory effects, and troponin, a particular marker for myocardial injury. Carbon monoxide (CO) poisoning is a major worldwide health problem because CO, a “silent killer,” has significant clinical consequences. Higher risk of cardiac problems, poorer clinical outcomes, and greater severity of carbon monoxide poisoning are all linked to elevated troponin and B-type natriuretic peptide levels. BNP’s adaptability in diagnosing cardiac dysfunction and directing decisions for hyperbaric oxygen therapy is complemented by troponin’s specificity in identifying CO-induced myocardial damage. When combined, they improve the accuracy of carbon monoxide poisoning diagnoses and offer a thorough understanding of cardiac pathophysiology.

Conclusions
To sum up, this review emphasizes the importance of troponin and B-type natriuretic peptide (BNP) as cardiac indicators during carbon monoxide exposure. While BNP predicts long-term cardiac problems, troponin is better at short-term morbidity and death prediction. When highly sensitive troponin I (hsTnI) and B-type natriuretic peptide are combined, the diagnostic accuracy of carbon monoxide poisoning patients is improved. One of the difficulties is evaluating biomarker levels since carbon monoxide poisoning symptoms are not always clear-cut. Accurate diagnosis and treatment depend on the investigation of new biomarkers and the use of standardized diagnostic criteria. The results advance the use of cardiovascular biomarkers in the intricate field of carbon monoxide exposure.
Adding merits of vacuum assisted biopsy in diagnosis and management of indeterminate breast micro-calcifications
Authors: Moustafa Amr Farouk Ibrahim , Emam Mohamed Mohsen , Mokhtar Omnia , Ibraheem Maher Hassan , Mohammed Ghada , Gomaa Mohamed Mohamed Mohamed 
Published: January 2024

Abstract
Background
Stereotactic guided biopsies have become the sampling method of choice in diagnosis of non-palpable breast microcalcifications which directly impact patients’ management plans and consequently morbidity and mortality.

Purpose
The purpose is to compare the diagnostic accuracy of VAB and CNB in diagnosis of indeterminate breast microcalcifications and subsequent management of cases of indeterminate breast micro-calcifications.

Methods
Retrospective review of stereotactic CNB and VAB was done, pathological data were classified as benign, high risk and malignant lesions and compared with gold standard surgical specimen. The influence on patients’ surgical planning was depicted.

Results
A total of 268 lesions were included in our study divided as 136 lesions that underwent VAB and 132 lesions that underwent CNB, for the VAB group the overall PPV was 100% (96–100% CI) and NPV was 95.8% (90–98% CI) with overall diagnostic accuracy of 97% (92–99% CI), while for the CNB group the PPV was 100% (95–100% CI) and NPV was 80.2% (74.2–85% CI) with overall diagnostic accuracy of 84.8% (77–90% CI). 4/136 VAB lesions did not match the surgical specimen malignant diagnosis this could be explained by their mean diameter of 9.725 ± 1.8 cm and 3.172 ± 1.84 cm which was found statistically significant P value of less than 0.0001. The percentage of re-operation in VAB group was 2.9% while in CNB group was 7.5%.

Conclusions
VAB is a superior diagnostic tool over CNB in diagnosis of indeterminate breast microcalcifications and reducing the percentage of re-operations which directly impacts the patient’s morbidity. Moreover, it can replace surgery in cases of benign lesions and totally resected high risk lesions especially when operations are contraindicated or refused by the patient, yet with strict follow up.