bluuebunny/crossref_metadata_2025_split huggingface dataset:
Atrolactic Acid
Authors: Eliel Ernest L. , Freeman Jeremiah P. 
Published: November 2003

Abstract

Atrolactic acid

product: atrolactic acid

solvent: 25 ml. of commercial pentane

product: atrolactic acid hemihydrate

reactant: Acetophenone (15–16.5 g., b.p. 92–94°/20 mm.)
Benzhydryl β‐Chloroethyl Ether
Authors: Sugasawa Shigehiko , Fujiwara Kunio 
Published: November 2003

Abstract

Benzhydryl β‐chloroethyl ether

reactant: 36 g. (0.45 mole) of ethylene chlorohydrin

reactant: 55 g. (0.30 mole) of benzhydrol

product: benzhydryl β‐chloroethyl ether
m
‐Nitrobiphenyl
Authors: Kaslow C. E. , Summers R. M. 
Published: November 2003

Abstract

m
‐Nitrobiphenyl

reactant: 276 g. (2 moles) of technical grade m‐nitroaniline

intermediate: 1‐(
m
‐nitrophenyl)‐3,3‐dimethyltriazene

product:
m
‐nitrobiphenyl
6‐Nitroveratraldehyde
Authors: Fetscher Charles A. 
Published: November 2003

Abstract

6‐Nitroveratraldehyde

reactant: Veratraldehyde,Org. Syntheses Coll. Vol. 2, 619 (1943). 70 g. (0.42 mole)

product: 6‐nitroveratraldehyde

byproduct: 6‐nitrosoveratric acid
2‐
p
‐Acetylphenylhydroquinone
Authors: Reynolds George A. , VanAllan J. A. 
Published: November 2003

Abstract

2‐
p
‐Acetylphenylhydroquinone

product: 2‐
p
‐acetylphenylquinone

product: 2‐
p
‐acetylphenylhydroquinone diacetate
β‐(
o
‐Carboxyphenyl)Propionic Acid
Authors: Page G. A. , Tarbell D. S. 
Published: November 2003

Abstract

β‐(
o
‐carboxyphenyl)propionic acid

intermediate:
o
‐carboxycinnamic acid

product: β‐(
o
‐carboxyphenyl)propionic acid

product: lactone of β‐hydroxy‐β‐(
o
‐carboxyphenyl)propionic acid (phthalideacetic acid)
Di‐
tert
‐butyl Malonate
Authors: McCloskey Allen L. , Fonken Gunther S. , Kluiber Rudolph W. , Johnson William S. , Raha Chittaranjan 
Published: November 2003

Abstract

Di‐
tert
‐butyl malonate

product: di‐
tert
‐butyl malonate

product:
tert
‐butyl acetate

product:
tert
‐butyl chloroacetate

product:
tert
‐butyl bromoacetate

product:
tert
‐butyl α‐chloropropionate

product:
tert
‐butyl
o
‐benzoylbenzoate

product: di‐
tert
‐butyl succinate

product: di‐
tert
‐butyl glutarate

product: di‐
tert
‐butyl β,β‐dimethylglutarate

intermediate: 28.0 g. (0.2 mole) of malonyl dichloride
Ethyl Enanthylsuccinate
Authors: Patrick Tracy M. , Erickson Floyd B. 
Published: November 2003

Abstract

Ethyl enanthylsuccinate

reactant: 228 g. (2.0 moles) of enanthaldehyde

product: ethyl enanthylsuccinate

product: γ‐oxocapric acid

product: γ‐caprilactone
sec
‐Butyl α‐
n
‐Caproylpropionate
Authors: Rinehart Kenneth L. 
Published: November 2003

Abstract

sec
‐butyl α‐
n
‐caproylpropionate

reactant: 38.9 g. (0.40 mole) of
n
‐capronitrile

reactant: 125.4 g. (0.60 mole) of
sec
‐butyl α‐bromopropionate

product:
sec
‐butyl α‐
n
‐caproylpropionate

product: 5‐pyrazolone
α‐(4‐Chlorophenyl)‐γ‐Phenylacetoacetonitrile
Authors: Coan Stephen B. , Becker Ernest I. 
Published: November 2003

Abstract

α‐(4‐Chlorophenyl)‐γ‐phenylacetoacetonitrile

product: α‐(4‐chlorophenyl)‐γ‐phenylacetoacetonitrile

product: α‐Phenyl‐γ‐phenyl‐

product: α‐Phenyl‐γ‐(4‐methylphenyl)‐

product: α‐Phenyl‐γ‐(4‐methoxyphenyl)‐

product: α‐Phenyl‐γ‐(4‐bromophenyl)‐

product: α‐Phenyl‐γ‐(4‐methylthiophenyl)‐

product: α‐(4‐Fluorophenyl)‐γ‐phenyl‐
N‐2‐Cyanoethylaniline
Authors: Cymerman‐Craig J. , Moyle M. 
Published: November 2003

Abstract

N‐2‐Cyanoethylaniline

product: N‐2‐cyanoethyl‐
p
‐anisidine

product: N‐2‐cyanoethyl‐
m
‐chloroaniline

product: N,N′‐bis‐2‐cyanoethyl‐
o
‐phenylenediamine

product: N,N′‐bis‐2‐cyanoethyl‐
p
‐phenylenediamine

product: N‐2‐Cyanoethylaniline
β‐Ethyl‐β‐methylglutaric acid
Authors: Farmer H. H. , Rabjohn Norman 
Published: November 2003

Abstractβ‐Ethyl‐β‐Methylglutaric acidintermediate: 280 g. (1.36 moles) of α,α′‐dicyano‐β‐ethyl‐β‐methylglutarimideproduct: β‐ethyl‐β‐methylglutaric acid
3‐Methyl‐4‐nitropyridine‐1‐oxide
Authors: Taylor E. C. , Crovetti Aldo J. 
Published: November 2003

Abstract

3‐Methyl‐4‐nitropyridine‐1‐oxide

reactant: One hundred and eighty grams (1.65 moles) of liquefied 3‐methylpyridine‐1‐oxide

reactant: 200 g. (2.15 moles) of freshly distilled 3‐methylpyridine

product: 3‐Methyl‐4‐nitropyridine‐1‐oxide
o
‐ and
p
‐Nitrobenzaldiacetate
Authors: Nishimura Tamio 
Published: November 2003

Abstract

o
‐ and
p
‐Nitrobenzaldiacetate

product:
p
‐
nitrobenzaldiacetate
.

reactant: 50 g. (0.36 mole) of
p
‐nitrotoluene

byproduct:
p
‐nitrobenzoic acid

product:
p
‐nitrobenzaldehyde

product:
o
‐nitrobenzaldiacetate
α‐Sulfopalmitic Acid
Authors: Weil J. K. , Bistline R. G. , Stirton A. J. 
Published: November 2003

Abstract

α‐Sulfopalmitic acid

reactant: Palmitic acid (200 g., 0.78 mole)

reactant: sulfur trioxide, 53 ml. (100 g., 1.25 moles)

product: α‐Sulfolauric acid

product: α‐Sulfomyristic acid

product: α‐Sulfopalmitic acid

product: α‐Sulfostearic acid

product: α‐Sulfobehenic acid
4‐Ethyl‐2‐methyl‐2‐octenoic acid
Authors: Rinehart Kenneth L. , Perkins Edward G. 
Published: November 2003

Abstract

4‐Ethyl‐2‐methyl‐2‐octenoic acid

reactant: 64.1 g. (0.50 mole) of 2‐ethylhexanal

byproduct: 4‐ethyl‐4‐hydroxy‐2‐methyloctanoic acid, γ‐lactone

product: 4‐ethyl‐2‐methyl‐2‐octenoic acid

intermediate: ethyl 4‐ethyl‐2‐methyl‐3‐hydroxyoctanoate

intermediate: ethyl 4‐ethyl‐2‐methyl‐2‐octenoate

intermediate: ethyl 4‐ethyl‐2‐methyl‐3‐octenoate
Ethyl α‐Nitrobutyrate
Authors: Kornblum Nathan , Blackwood Robert K. 
Published: November 2003

Abstract

Ethyl α‐nitrobutyrate

reactant: Ethyl α‐bromobutyrate (58.5 g., 0.30 mole)

product: ethyl α‐nitrobutyrate

product: Ethyl α‐nitropropionate

product: Ethyl α‐nitrocaproate

product: Ethyl α‐nitroisobutyrate

product: Ethyl α‐nitroisovalerate

product: Ethyl α‐phenyl‐α‐nitroacetate
3‐(
o
‐Chloroanilino)Propionitrile
Authors: Heininger S. A. 
Published: November 2003

Abstract

3‐(
o
‐Chloroanilino)propionitrile

reactant: 255 g. (2.0 moles) of
o
‐chloroaniline

product: 3‐(
o
‐chloroanilino) propionitrile
N‐Ethyl‐
p
‐Chloroaniline
Authors: Roberts Royston M. , Vogt Paul J. 
Published: November 2003

Abstract

N‐ethyl‐
p
‐chloroaniline

intermediate:
N‐Ethyl‐p‐chloroformanilide.

product: N‐ethyl‐
p
‐chloroaniline

byproduct: ethyl N‐
p
‐chlorophenylformimidate

: N‐Methylaniline

: N‐Ethylaniline

: N‐Isoamylaniline

: N‐Methyl‐
m
‐toluidine

: N‐Ethyl‐
m
‐toluidine

: N‐Methyl‐
p
‐chloroaniline
β‐Methylglutaric Anhydride
Authors: Cason James 
Published: November 2003

Abstract

β‐Methylglutaric anhydride

reactant: 115 g. (0.72 mole) of diethyl malonate

reactant: 60 g. (0.60 mole) of methyl crotonate

product: β‐Methylglutaric anhydride

product: methyl hydrogen β‐methylglutarate
9‐Methylfluorene
Authors: Schoen Kurt L. , Becker E. I. 
Published: November 2003

Abstract

9‐Methylfluorene

reactant: 113 g. (0.68 mole) of fluorene

product: 9‐methylfluorene

product: 9‐Ethylfluorene

product: 9‐
n
‐Propylfluorene

product: 9‐
n
‐Butylfluorene

product: 9‐
n
‐Pentylfluorene

product: 9‐
n
‐Hexylfluorene

product: 9‐
n
‐Heptylfluorene

product: 9‐
n
‐Octadecylfluorene
Phenylpropargylaldehyde Diethyl Acetal
Authors: Howk B. W. , Sauer J. C. 
Published: November 2003

Abstract

Phenylpropargylaldehyde diethyl acetal

product: phenylpropargylaldehyde diethyl acetal

product: cyclohexylmethylpropiolaldehyde diethyl acetal

product: phenylethynyl
n
‐butyl dimethyl ketal

product: phenylethynyl methyl diethyl ketal

product:
n
‐Butylpropiolaldehyde diethyl acetal
α,α,β‐Triphenylpropionitrile
Authors: Hauser C. R. , Dunnavant W. R. 
Published: November 2003

Abstract

α,α,β‐Triphenylpropionitrile

reactant: 30.5 g. (0.24 mole) of benzyl chloride

product: α,α,β‐triphenylpropionitrile
3‐Acetyloxindole
Authors: Bunnett J. F. , Hrutfiord B. F. , Williamson S. M. 
Published: November 2003

Abstract

3‐Acetyloxindole

reactant: 105.8 g. (0.5 mole) of
o
‐acetoacetochloroanilide

product: 3‐acetyloxindole

: 2‐phenylbenzothiazole

: 2‐phenylbenzoxazole

: 1‐cyanobenzocyclobutene

: 1‐methyl‐2,1‐benzisothiazoline 2,2‐dioxide
3‐Chloro‐2,2,3‐trifluoropropionic Acid
Authors: England D. C. , Melby L. R. 
Published: November 2003

Abstract

3‐Chloro‐2,2,3‐trifluoropropionic acid

product: 3‐chloro‐2,2,3‐trifluoropropionic acid

byproduct: 3‐chloro‐2,2,3‐trifluoropropionamide
4,4′‐Diaminoazobenzene
Authors: Santurri Pasco , Robbins Frederick , Stubbings Robert 
Published: November 2003

Abstract

4,4′‐Diaminoazobenzene

reactant: 29.0 g. (0.19 mole) of
p
‐aminoacetanilide

intermediate: 4,4′‐bis(acetamido)azobenzene

product: 4,4′‐diaminoazobenzene
1,4‐Diphenyl‐1,3‐Butadiene
Authors: McDonald Richard N. , Campbell Tod W. 
Published: November 2003

Abstract

1,4‐Diphenyl‐1,3‐Butadiene

intermediate: 60.0 g. (0.145 mole) of triphenylcinnamylphosphonium chloride

product: 1‐(
p
‐tolyl)‐4‐phenylbutadiene

product: 1‐(4‐methoxyphenyl)‐4‐phenylbutadiene

product: 1‐(4‐acetamidophenyl)‐4‐phenylbutadiene

product: 1,4‐Diphenylbutadiene
Ethyl 6,7‐Dimethoxy‐3‐Methylindene‐2‐Carboxylate
Authors: Koo John 
Published: November 2003

Abstract

Ethyl 6,7‐dimethoxy‐3‐methylindene‐2‐carboxylate

product: ethyl 6,7‐dimethoxy‐3‐methylindene‐2‐carboxylate
3‐Hydroxyquinoline
Authors: Cragoe Edward J. , Robb Charles M. 
Published: November 2003

Abstract3‐Hydroxyquinolinereactant: 249 g. (2.83 moles) of pyruvic acidintermediate: chloropyruvic acidintermediate: 3‐Hydroxycinchoninic acid (part B) (94.6 g., 0.5 mole)product: 3‐hydroxyquinolinereactant: monohydrate
N‐Phthalyl‐
L
‐β‐phenylalanine
Authors: Bose Ajay K. 
Published: November 2003

Abstract

N‐phthalyl‐
L
‐β‐phenylalanine

product: N‐phthalyl‐
L
‐β‐phenylalanine

reactant: 16.5 g. (0.1 mole) of
L
‐phenylalanine

product:
N
‐phthalyl‐β‐alanine

product: N‐phthalyl‐
L
‐alanine

product: ethyl ester of N‐phthalylglycine
p
‐Quinquephenyl
Authors: Campbell Tod W. , McDonald Richard N. 
Published: November 2003

Abstract

p
‐Quinquephenyl

intermediate: 70 g. (0.10 mole) of
p
‐xylylene‐bis(triphenylphosphonium chloride)

intermediate: 3.34 g. (0.010 mole) of 1,4‐bis‐(4‐phenylbutadienyl)benzene

reactant: 1,4‐bis‐[4‐(
p
‐tolyl)butadienyl]benzene

reactant: 1,4‐bis‐[4‐(3‐nitrophenyl)butadienyl]‐benzene

reactant: 1,4‐bis‐(3‐methyl‐4‐phenylbutadienyl)benzene

product:
p
‐Quinquephenyl
2,7‐Dimethyl‐2,7‐Dinitroöctane
Authors: Sharkey W. H. , Langkammerer C. M. 
Published: November 2003

Abstract

2,7‐Dimethyl‐2,7‐dinitroöctane

reactant: 4‐methyl‐4‐nitrovaleric acid

product: 2,7‐dimethyl‐2,7‐dinitroöctane
1,6‐Dioxo‐8a‐Methyl‐1,2,3,4,6,7,8,8a‐Octahydronaphthalene
Authors: Ramachandran S. , Newman Melvin S. 
Published: November 2003

Abstract

1,6‐Dioxo‐8a‐methyl‐1,2,3,4,6,7,8,8a‐octahydronaphthalene

product: 1,6‐dioxo‐8a‐methyl‐1,2,3,4,6,7,8,8a‐octahydronaphthalene

intermediate: 2‐methyl‐2‐(3′‐oxobutyl)‐1,3‐cyclohexanedione

solvent: hexane
2‐Oxa‐7,7‐dichloronorcarane
Authors: Parham William E. , Schweizer Edward E. , Mierzwa Sigmund A. 
Published: November 2003

Abstract

2‐Oxa‐7,7‐dichloronorcarane

solvent: 100‐ml. portions of petroleum ether

product: 2‐oxa‐7,7‐dichloronorcarane
1,1,1‐Trifluoroheptane
Authors: Hasek W. R. 
Published: November 2003

Abstract

1,1,1‐Trifluoroheptane

product: 1,1,1‐Trifluoroheptane

product: 1,1,1‐Trifluorododecane

product: 1,1,1‐Trifluorohexadecane

product: 1,1,1‐Trifluoro‐3,5,5‐trimethylhexane

product: (4,4,4‐Trifluorobutyl)cyclohexane

product: 1,1,1,10,10,10‐Hexafluorodecane

product: 1,1,1,6,6,6‐Hexafluoro‐3‐hexene

product:
p
‐Bis(trifluoromethyl)benzene

product: 2,4‐Bis(trifluoromethyl)chlorobenzene

product:
p
‐Trifluoromethylnitrobenzene
1‐Benzylpiperazine
Authors: Craig J. Cymerman , Young R. J. 
Published: November 2003

Abstract

1‐Benzylpiperazine

intermediate: piperazine dihydrochloride monohydrate

intermediate: 1‐benzylpiperazine dihydrochloride

product: 1‐benzylpiperazine

byproduct: 1‐benzyl‐4‐piperazinium chloride

byproduct: 1‐benzoyl‐4‐benzylpiperazine hydrochloride
2,2‐Difluorosuccinic Acid
Authors: Raasch M. S. , Castle J. E. 
Published: November 2003

Abstract

2,2‐Difluorosuccinic acid

intermediate: 1,1,2‐trichloro‐2,3,3‐trifluorocyclobutane

intermediate: 1‐chloro‐2,3,3‐trifluorocyclobutene

product: 2,2‐difluorosuccinic acid
α‐Benzylidene‐γ‐Phenyl‐Δ
β,γ
‐Butenolide
Authors: Filler Robert , Piasek Edmund J. , Leipold Hans A. 
Published: November 2003

Abstract

α‐Benzylidene‐γ‐phenyl‐Δ
β,γ
‐butenolide

product: α‐benzylidene‐γ‐phenyl‐Δ
β,γ
‐butenolide
p
‐Hydroxyphenylpyruvic Acid
Authors: Billek Gerhard 
Published: November 2003

Abstract

p
‐Hydroxyphenylpyruvic acid

reactant: 6.11 g. (0.050 mole) of
p
‐hydroxybenzaldehyde

intermediate: 5‐(
p
‐hydroxybenzal)hydantoin

product:
p
‐hydroxyphenylpyruvic acid
1,2,3,4,5‐Pentachloro‐5‐ethylcyclopentadiene
Authors: Mark V. , Wann R. E. , Godt H. C. 
Published: November 2003

Abstract

1,2,3,4,5‐Pentachloro‐5‐ethylcyclopentadiene

reactant: 183 g. (1.10 moles) of triethyl phosphite

solvent: 200 ml. of petroleum ether

product: 1,2,3,4,5‐pentachloro‐5‐ethylcyclopentadiene

reactant: diethyl hydrogen phosphite

reactant: triethyl phosphate

byproduct: diethyl phosphorochloridate [chlorodiethoxyphosphorus (V) oxide]
7‐
t
‐Butoxynorbornadiene
Authors: Story Paul R. , Fahrenholtz Susan R. 
Published: November 2003

Abstract

7‐
t
‐Butoxynorbornadiene

solvent: 500 ml. of benzene

product: 7‐t‐butyoxynorbornadiene

product: 7‐benzoxynorbornadiene
t
‐Butyl azodiformate
Authors: Carpino Louis A. , Crowley Paul J. 
Published: November 2003

Abstract

t
‐Butyl azodiformate

solvent: 60 ml. of pyridine

intermediate: 23.2 g. (0.1 mole) of crude
t
‐butyl hydrazodiformate

solvent: 35–40 ml. of petroleum ether

solvent: ligroin

product:
t
‐Butyl azodiformate
Ethyl β‐Hydroxy‐β,β‐Diphenylpropionate
Authors: Dunnavant W. R. , Hauser Charles R. 
Published: November 2003

Abstract

Ethyl β‐hydroxy‐β,β‐diphenylpropionate

product: ethyl β‐hydroxy‐β,β‐diphenylpropionate

reactant: benzophenone

product: Isopropyl and
t
‐butyl β‐hydroxy‐β,β‐diphenylpropionate
2
a
‐Thiohomophthalimide
Authors: Smith P. A. S. , Kan R. O. 
Published: November 2003

Abstract

2
a
‐Thiohomophthalimide

intermediate:
Phenylacetyl isothiocyanate

product:
2a‐Thiohomophthalimide

reactant: Lead thiocyanate

product: 6‐methyl‐1
a
‐thiophthalimide

product: 4,6‐dimethyl‐1
a
‐thiophthalimide

product: 5‐methyl‐2
a
‐thiohomophthalimide

product: 4‐methyl‐2
a
‐thiohomophthalimide

product: 5‐methoxy‐2
a
‐thiohomophthalimide

product: 4‐chloro‐2‐thiohomophthalimide

product: 1
a
‐phenyl‐2
a
‐thiohomophthalimide

product: 1
a
‐thio‐1,2‐naphthalimide

product: 2
a
‐thio‐1‐homo‐1,2‐naphthalimide

product: thiophene‐2
a
‐thio‐2,3‐dicarboximide
Benzoyl Fluoride
Authors: Olah George A. , Kuhn Stephen J. 
Published: November 2003

AbstractBenzoyl fluorideproduct: benzoyl fluorideproduct: Propionyl fluorideproduct:n‐Butyryl fluorideproduct: Isobutyryl fluorideproduct: Valeryl fluorideproduct: Isovaleryl fluorideproduct: Caproyl fluorideproduct: Heptanoyl fluorideproduct: Octanoyl fluorideproduct: Pelargonyl fluorideproduct: Decanoyl fluorideproduct: Fluoroacetyl fluorideproduct: Chloroacetyl fluorideproduct: Dichloroacetyl fluorideproduct: Trichloroacetyl fluorideproduct: Bromoacetyl fluorideproduct: Phthaloyl fluorideproduct: Phenylacetyl fluoride
18,20‐Lactone of 3β‐Acetoxy‐20β‐Hydroxy‐5‐Pregnene‐18‐Oic Acid
Authors: Heusler K. , Wieland P. , Meystre Ch. 
Published: November 2003

Abstract

18,20‐Lactone of 3β‐acetoxy‐20β‐hydroxy‐5‐pregnene‐18‐oic acid

intermediate:
3β‐Acetoxy‐20β‐hydroxy‐5‐pregnene

reactant: 71.7 g. (0.2 mole) of pregnenolone acetate

intermediate:
3β‐Acetoxy‐18‐iodo‐ and 18‐hydroxy‐18,20β‐oxido‐5‐pregnene

product: 18,20‐lactone of 3β‐acetoxy‐20β‐hydroxy‐5‐pregnene‐18‐oic acid
β‐Isovalerolactam‐N‐Sulfonyl Chloride and β‐Isovalerolactam
Authors: Graf Roderich 
Published: November 2003

Abstract

β‐Isovalerolactam‐N‐sulfonyl chloride and β‐isovalerolactam

product: β‐isovalerolactam‐N‐sulfonyl chloride

product: β‐
Isovalerolactam
Methyl Phenyl Sulfoxide
Authors: Johnson Carl R. , Keiser Jeffrey E. 
Published: November 2003

Abstract

Methyl phenyl sulfoxide

reactant: methyl phenyl sulfoxide

product: Methyl 4‐ketopentyl sulfoxide

product: Thian 1‐oxide

product: 1,4‐Oxathian 1‐oxide

product: Bis(2‐diethylaminoethyl)sulfoxide

product: Acetoxymethyl methyl sulfoxide

product: 1‐Benzylsulfinyl‐2‐propanone

product: Phenylsulfinylacetic acid

product: Benzyl sulfoxide

product: Ethyl sulfoxide

product: Ethyl phenyl sulfoxide
2‐Nitrocarbazole
Authors: Mendenhall G. David , Smith Peter A. S. 
Published: November 2003

Abstract

2‐Nitrocarbazole

intermediate:
o
‐aminobiphenyl

intermediate:
o‐Amino‐p′‐nitrobiphenyl

intermediate:
o‐Azido‐p′‐nitrobiphenyl

product: 2‐Nitrocarbazole
Trimethyloxonium 2,4,6‐Trinitrobenzenesulfonate
Authors: Helmkamp G. K. , Pettitt D. J. 
Published: November 2003

Abstract

Trimethyloxonium 2,4,6‐trinitrobenzenesulfonate

reactant: 2,4,6‐Trinitrobenzenesulfonic acid (14.7 g., 0.050 mole)

product: trimethyloxonium 2,4,6‐trinitrobenzenesulfonate

byproduct: methyl 2,4,6‐trinitrobenzenesulfonate
2,3,5‐Triphenylisoxazolidine
Authors: Brüning Ingrid , Grashey Rudolf , Hauck Hans , Huisgen Rolf , Seidl Helmut 
Published: November 2003

Abstract

2,3,5‐Triphenylisoxazolidine

intermediate: N,α‐diphenylnitrone

product: 2,3,5,5‐tetraphenylisoxazolidine

product: ethyl 2,3‐diphenyl‐5‐methylisoxazolidine‐4‐carboxylate

product: 2,3,5‐Triphenylisoxazolidine
1,2,3‐Benzothiadiazole 1,1‐Dioxide
Authors: Wittig G. , Hoffmann R. W. 
Published: November 2003

Abstract

1,2,3‐Benzothiadiazole 1,1‐dioxide

intermediate: 2‐nitrobenzenesulfinic acid

intermediate: sodium 2‐aminobenzenesulfinate

product: 1,2,3‐benzothiadiazole 1,1‐dioxide
Cyclohexylidenecyclohexane
Authors: Turro Nicholas J. , Leermakers Peter A. , Vesley George F. 
Published: November 2003

Abstract

Cyclohexylidenecyclohexane

intermediate: 15 g. (0.068 mole) of dispiro[5.1.5.1]tetradecane‐7,14‐dione

product: cyclohexylidenecyclohexane
3,5‐Dinitro‐
o
‐Tolunitrile
Authors: Olah George A. , Kuhn Stephen J. 
Published: November 2003

Abstract

3,5‐Dinitro‐
o
‐tolunitrile

reactant: 22 ml. (22 g., 1.10 moles) of cold, liquid, anhydrous hydrogen fluoride

intermediate: nitronium tetrafluoroborate

product:
3,5‐Dinitro‐o‐tolunitrile
2‐Phenyl‐5‐Oxazolone
Authors: VandenBerg G. E. , Harrison J. B. , Carter H. E. , Magerlein B. J. 
Published: November 2003

Abstract

2‐Phenyl‐5‐oxazolone

solvent: Skellysolve B

product: 2‐phenyl‐5‐oxazolone
3(5)‐Aminopyrazole
Authors: Dorn H. , Zubek A. 
Published: November 2003

Abstract

3(5)‐Aminopyrazole

intermediate: β‐cyanoethylhydrazine

intermediate: 183 g. (1.00 mole) of 3‐amino‐3‐pyrazoline sulfate

intermediate: 191 g. (0.80 mole) of 3‐imino‐1‐(
p
‐tolylsulfonyl)‐pyrazolidine

byproduct: sodium
p
‐toluenesulfinate

product: 3(5)‐aminopyrazole
t
‐Butyl Diazoacetate
Authors: Regitz Manfred , Hocker Jürgen , Liedhegener Annemarie 
Published: November 2003

Abstract

t
‐Butyl diazoacetate

intermediate:
p
‐toluenesulfonyl azide

solvent: 75.8 g. (0.75 mole) of previously distilled triethylamine

intermediate: 92.6 (0.50 mole) of
t
‐butyl α‐diazoacetoacetate

byproduct:
p
‐toluenesulfonamide

product:
t
‐butyl diazoacetate
2‐
n
‐Butyl‐2‐methylcyclohexanone
Authors: Boatman S. , Harris T. M. , Hauser C. R. 
Published: November 2003

Abstract

2‐
n
‐Butyl‐2‐methylcyclohexanone

reactant: 123 g. (1.10 moles) of 2‐methylcyclohexanone

reactant: 81.4 g. (1.10 moles) of ethyl formate

intermediate: Sodio‐2‐formyl‐6‐methylcyclohexanone

reactant: 28.2 g. (0.21 mole) of
n
‐butyl bromide

product: 2‐
n
‐butyl‐2‐methylcyclohexanone

byproduct: 2‐formyl‐6‐
n
‐butyl‐6‐methylcyclohexanone

product: 2,2‐Dimethylcyclohexanone

product: 2‐benzyl‐2‐methylcyclohexanone
1‐Cyanobenzocyclobutene
Authors: Skorcz J. A. , Kaminski F. E. 
Published: November 2003

Abstract

1‐Cyanobenzocyclobutene

product: 1‐cyanobenzocyclobutene

product: ethyl 2‐(
o
‐chlorobenzyl)cyanoacetate

product: 2‐(
o
‐chlorobenzyl)cyanoacetic acid

product:
o
‐chlorohydrocinnamonitrile
7,7‐Dimethoxybicyclo[2.2.1]heptene
Authors: Gassman P. G. , Marshall J. L. 
Published: November 2003

Abstract

7,7‐Dimethoxybicyclo[2.2.1]heptene

intermediate: 5,5‐dimethoxy‐1,2,3,4‐tetrachlorocyclopentadiene

intermediate: 106 g. (0.36 mole) of 7,7‐dimethoxy‐1,2,3,4‐tetrachlorobicyclo[2.2.1]hept‐2‐ene

product: 7,7‐dimethoxybicyclo[2.2.1]heptene
1,1‐Diphenylcyclopropane
Authors: Jorgenson M. J. , Thacher A. F. 
Published: November 2003

Abstract

1,1‐Diphenylcyclopropane

intermediate: β‐phenylcinnamic acid

product: diphenylcyclopropane

R = C
6
H
5
, R′ = CH
3
Ar = C
6
H
5

R = R′ = CH
3
Ar = m‐CF
3
C
6
H
4

R = R′ = CH
3
Ar = C
6
H
5

R = R′ = H Ar = C
6
H
5
a

R = R′ = CH
3
Ar = 3,4‐Cl
2
C
6
H
3
D
‐2‐Oxo‐7,7‐dimethyl‐1‐vinylbicyclo[2.2.1]heptane
Authors: Fischer Nikolaus , Opitz G. 
Published: November 2003

Abstract

D
‐2‐Oxo‐7,7‐dimethyl‐1‐vinylbicyclo[2.2.1]heptane

reactant: 13.0 g. (0.052 mole) of
D
‐camphor‐10‐sulfonyl chloride

byproduct: Triethylamine hydrochloride

intermediate: episulfone

product:
D
‐2‐Oxo‐7,7‐dimethyl‐1‐vinylbicyclo[2.2.2]heptane
2‐
t
‐Butyl‐3‐phenyloxazirane
Authors: Emmons W. D. , Pagano A. S. 
Published: November 2003

Abstract

2‐
t
‐Butyl‐3‐phenyloxazirane

intermediate: N‐
t
‐butylbenzaldimine

product: 2‐
t
‐butyl‐3‐phenyloxazirane
Crotyl Diazoacetate
Authors: Blankley C. John , Sauter Frederick J. , House Herbert O. 
Published: November 2003

AbstractCrotyl diazoacetateintermediate:Glyoxylic acid p‐toluenesulfonylhydrazone.intermediate:p‐toluenesulfonylhydrazone of glyoxylic acid chloridesolvent: petroleum ether (b.p. 30–60°; about 50 ml.product:Crotyl diazoacetate.reactant: 7.80 g. (0.077 mole) of redistilled triethylamine
Dimethyl Cyclohexanone‐2,6‐Dicarboxylate
Authors: Balasubrahmanyam S. N. , Balasubramanian M. 
Published: November 2003

Abstract

Dimethyl cyclohexanone‐2,6‐dicarboxylate

reactant: Cyclohexanone (20.0 g., 0.204 mole)

product: Dimethyl cyclohexanone‐2, 6‐dicarboxylate
Diphenylcarbodiimide, Method
II
Authors: Rajagopalan S. , Advani B. G. , Talaty C. N. 
Published: November 2003

Abstract

Diphenylcarbodiimide, Method II

intermediate: N‐sulfinylaniline

reactant: 50 g. (0.41 mole) of benzaldoxime

solvent: 150 ml. of petroleum ether

intermediate: benzohydroxamoyl chloride

intermediate: triethylamine hydrochloride

product: diphenyl carbodiimide
3‐Isoquinuclidone
Authors: Pearlman W. M. 
Published: November 2003

Abstract

3‐Isoquinuclidone

catalyst: 2 g. of 10% rhodium‐0.1% palladium on carbon

intermediate:
cis
‐ and
trans
‐4‐aminocyclohexanecarboxylic acid

product: 3‐isoquinuclidone
tert
‐Butyl Azidoformate
Authors: Insalaco Michael A. , Tarbell D. Stanley 
Published: November 2003

Abstract

tert
‐Butyl azidoformate

reactant: 20.6 g. (0.120 mole) of pure diethyl phosphorochloridate

solvent: 120 ml. of anhydrous dimethyl sulfoxide

reactant: 8.1 g (0.10 mole) of powdered potassium azide

intermediate: 25.4 g. (0.100 mole) of
tert
‐butylcarbonic diethylphosphoric anhydride

product:
tert
‐butyl azidoformate
m
‐Chloroperbenzoic Acid
Authors: McDonald Richard N. , Steppel Richard N. , Dorsey James E. 
Published: November 2003

Abstract

m
‐Chloroperbenzoic acid

reactant: 52.5 g. (0.300 mole) of
m
‐chlorobenzoyl chloride

product:
m
‐chloroperbenzoic acid
α,α′‐Dibromodibenzyl Sulfone
Authors: Carpino Louis A. , McAdams Louis V. 
Published: November 2003

Abstract

α,α′‐Dibromodibenzyl sulfone

solvent: 250–300 ml. of ligroin

intermediate: α‐bromophenylacetic acid

intermediate: 24.9 g. (0.0824 mole) of crude α,α′‐diphenylthiodiglycolic acid

product: α,α′‐dibromodibenzyl sulfone

intermediate: dibenzyl sulfide
cis
‐2‐Phenylcyclopropanecarboxylic Acid
Authors: Kaiser Carl , Weinstock Joseph , Olmstead M. P. 
Published: November 2003

Abstract

cis
‐2‐Phenylcyclopropanecarboxylic acid

reactant: 163 g. (1.57 moles) of styrene

intermediate: 155 g. (0.816 mole) of ethyl
cis
‐ and
trans
‐2‐phenylcyclopropanecarboxylate

product:
cis
‐2‐phenylcyclopropanecarboxylic acid

product:
trans
‐2‐Phenylcyclopropanecarboxylic acid