bluuebunny/crossref_metadata_2025_split huggingface dataset:
The devastation of Lumpy skin disease in third world countries: a mini – review on the current status of the disease focusing phytochemicals
Authors: Menahil Rauf  , Zoya Zaheer  , Yaseen Hussain  , Amjad Hayat Khan  
Published: February 2024

Lumpy skin disease is a rising bovine viral illness that is widespread in most African and Middle Eastern nations, with a high probability of disease transmission throughout the Asia and Europe. The causative agent is capripoxivirus endangering hundreds of dairy cattle across the country in recent years. The LSD virus infects cattle and buffaloes and results in nodular skin sores all over their bodies. This results in chronic debility, decreased milk supply, poor development, infertility, abortion, and other issues in cattle and buffaloes infrequently leading to death of animals. The only infected animal species are cattle and water buffalo, both of which have high morbidity and low mortality rates. However, mortality rates are greater in calf populations. LSD causes sterility in males and abortions in female cattle. This mini review highlights existing information on epidemiology, pathogenesis, clinical manifestations, and potential role of phytochemicals particularly turmeric and aloe vera in treating lumpy skin disease.
Expert Opinion on the Prescription Practice of Rabeprazole and Other Common Proton Pump Inhibitors for Patients with Gastroesophageal Reflux Disease
Authors: Manjula S  , Krishna Kumar M  
Published: February 2024

Objective: The current survey-based study aims to provide further insights on expert opinion regarding the commonly prescribed PPIs in clinical practice, with a specific focus on the use of oral rabeprazole 20 mg as a treatment for gastroesophageal reflux disease (GERD) maintenance therapy in Indian settings.
Methodology: The questionnaire-based survey involving 25 questions collected perspectives of experts across various regions of India regarding the prescription practice of rabeprazole 20 mg and other proton-pump inhibitors (PPIs) for treating GERD symptoms.
Results: Out of 512 study participants, 44% reported obesity as the common comorbid condition observed in GERD patients, while 28% noted co-morbid diabetes mellitus. According to 68% of the respondents, rabeprazole demonstrated superiority over other PPIs in terms of quicker onset of action, maintaining intragastric pH >4 over 24 hours’ post-dose, and reduced nighttime heartburn. For GERD patients with functional dyspepsia and gastroparesis, 52% of responders favored the addition of domperidone as a prokinetic drug to the PPI treatment. Moreover, the majority of participants (61.91%) observed that rabeprazole 20 mg did not cause a delay in stomach emptying, nor did it raise somatostatin levels or alter baseline motilin levels in GERD patients. These findings underscore the effectiveness of rabeprazole 20 mg in comparison to omeprazole and lansoprazole.
Conclusion: Experts recommended rabeprazole 20 mg as the preferred treatment option over omeprazole and lansoprazole for GERD patients with coexisting obesity and diabetes mellitus conditions. Additionally, over half of the respondents reported using a combination of domperidone and other PPIs for GERD patients with functional dyspepsia and gastroparesis.
Efficacy of Acupuncture in Chronic Low Back Pain Treatment: A Literature Review
Authors: Carretta Lucca Tamara Alves , Teixeira Pedro Rodrigues , Dias Ana Clara Pirovani , Devens Carolina Mesquita , Rones Luiza Norbim , Bonacossa Camila Kafuri , Barbosa Cássio Newton Bomfim 
Published: February 2024

Aims: To evaluate the effects of the use of acupuncture as a treatment of chronic low back pain.
Methodology: This study follows the integrative methodology of literature review, seeking articles published on PubMed, using keywords from Medical Subject Headings (MeSH) to form the search Formula: Acupuncture AND "low back pain". Inclusion criteria were randomized controlled trials published between 2018 and 2023, with free full text available in english or portuguese. The exclusion criteria was not answering this review’s orienting question.
Results: Several studies analyzed the efficacy of different acupuncture and electroacupuncture approaches in the treatment of chronic low back pain. One study highlighted invasive laser acupuncture with different wavelengths, revealing improvements in pain and disability scales after 4 weeks. Another research compared electroacupuncture at various frequencies, observing similar reductions in pain between the groups. Combined acupuncture (hands and ear) was more effective than usual medical treatment, showing greater reduction in pain and cure rate. Both electroacupuncture and manual acupuncture also demonstrated efficacy in reducing pain intensity and quality. Acupuncture with embedded wires stood out, showing positive and rapid results in chronic low back pain. Another study revealed that both electroacupuncture and a placebo had positive impacts on pain intensity.
Conclusion: Even though there are multiple forms of acupuncture used throughout the studies, and even those that appear on multiple studies are done differently on those appearances, all are used as a way to reduce CLBP. In that sense, the positive effects from using traditional acupuncture or some different form of acupuncture as a treatment for CLBP is highlighted by the results from the studies that were a part of this review.
Hypervalente Iodverbindungen in der Synthese: Möglichkeiten und Grenzen
Authors: Wirth Thomas 
Published: April 2005

AbstractVielfältige Veröffentlichungen belegen die beeindruckende Entwicklung der Chemie hypervalenter Iodverbindungen in den vergangenen Jahren. Auch wenn die Synthese der ersten hypervalenten Iodverbindung bereits über hundert Jahre zurückliegt, werden die Reaktivitäten dieser Verbindungsklasse sowie der Einsatz dieser metallfreien Reagentien in der organischen Synthese immer noch intensiv untersucht. Dieser Beitrag fasst neue Erkenntnisse und Fortschritte zusammen, die die zukünftige Forschung beeinflussen und zu neuen Anwendungen hypervalenter Iodverbindungen in der Synthese führen werden.
Structure and Bonding of Li1.42(5)Pd2Sn5.58(5): A Lithium Intercalated Palladium Stannide.
Authors: Sreeraj Puravankara , Hoffmann Rolf‐Dieter , Wu Zhiyun , Poettgen Rainer , Haeussermann Ulrich 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Unexpected Ligand Substitutions in the Cluster Core {Re6Se8}: Synthesis and Structure of the Novel Cluster Compound Cs11(H3O) [Re6Se4O4Cl6] 3×4H2O.
Authors: Yarovoi S. S. , Mironov Y. V. , Solodovnikov S. F. , Naumov D. Y. , Moroz N. K. , Kozlova S. G. , Simon A. , Fedorov V. E. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Asymmetric Alkylation of Aldehydes Catalyzed by Novel Dinuclear Bis‐BINOLate Titanium(IV) Complexes.
Authors: Harada Toshiro , Kanda Kousou , Hiraoka Yuuki , Marutani Yasuhisa , Nakatsugawa Masashi 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Conversions of 2‐(2‐Oxocyclohexylcarbonyl)benzoic Acid Derivatives to Pyrazolo[5,1‐a]isoindole and Pyrimidine Rings.
Authors: Voitenko Z. V. , Pokholenko O. A. , Kondratov I. S. , Kovtunenko V. O. , Andre C. , Wolf J. G. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Iron‐Catalyzed Coupling Reaction Between 1,1‐Dichloro‐1‐alkenes and Grignard Reagents.
Authors: Dos Santos Mickael , Franck Xavier , Hocquemiller Reynald , Figadere Bruno , Peyrat Jean‐Francois , Provot Olivier , Brion Jean‐Daniel , Alami Mouad 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis, Characterization and Biological Activity of 1,3,4‐Substituted 2‐Azetidinones.
Authors: Pandey V. K. , Gupta V. D. , Upadhyay Mrinalini , Upadhyay Mridula , Singh V. K. , Tandon Meenal 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 4‐(R)‐Naphthalene‐2‐yloxy‐1‐(1‐phenyl‐(S)‐ethyl)‐pyrrolidin‐3‐(R)‐ol and 4‐(S)‐Naphthalen‐2‐yloxy‐1‐(1‐phenyl‐(S)‐ethyl)‐pyrrolidin‐3‐(S)‐ol: Versatile Chiral Intermediateds for Synthesis.
Authors: Holsworth Daniel D. , Stier Michael , Wang Wei , Edmunds Jeremy J. , Li Tingsheng , Maiti Samarendra N. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Carbonic Anhydrase Inhibitors. Novel Sulfanilamide/Acetazolamide Derivatives Obtained by the Tail Approach and Their Interaction with the Cytosolic Isozymes I and II, and the Tumor‐Associated Isozyme IX.
Authors: Turkmen Hasan , Durgun Mustafa , Yilmaztekin Serpil , Emul Mahmut , Innocenti Alessio , Vullo Daniela , Scozzafava Andrea , Supuran Claudiu T. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 6‐Hetaryl‐5,5‐dialkyl‐3,3‐dimethyltetrahydropyran‐2,4‐diones by Reformatsky Reaction.
Authors: Shchepin V. V. , Korzun A. E. , Sazhneva Yu. Kh. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Bi(OTf)3‐[Bmim]PF6: A Novel and Recyclable Catalytic System for the Diastereoselective Synthesis of cis‐Fused Pyrano and Furanobenzopyrans.
Authors: Yadav J. S. , Reddy B. V. S. , Reddy P. Narayana 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Facile Synthesis of Some New Thiazolo[3,2‐a]pyridines Containing Pyrazolyl Moiety and Their Antimicrobial Activity.
Authors: El‐Emary T. I. , Khalil A. , El‐Hag Ali G. A. M. , El‐Adasy A. A. A. M. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
3‐Arylidene‐pent‐2,4‐dione in the Synthesis of Heterocyclic Systems. Facile One‐Pot Synthesis of Novel Pentasubstituted 1,8‐Naphthyridine‐2‐thione.
Authors: Khalil Mohamed Ali 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Condensed Isoquinolines. Part 17. Enamine Properties of Benzimidazo[1,2‐b]isoquinolin‐11(5H)‐one in Alkylation Reactions.
Authors: Potikha L. M. , Shkilna N. V. , Kisil V. M. , Kovtunenko V. A. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Studies on Pyrazine Derivatives. Part 40. Synthesis, Reactivity, and Tuberculostatic Activity of 4‐Hydroxyalkyl‐5‐pyrazinyl‐4H‐[1,2,4]‐triazole‐3‐thiones.
Authors: Foks Henryk , Janowiec Mieczyslaw , Zwolska Zofia , Augustynowicz‐Kopec Ewa 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Substituted and Spiro‐Anellated Perhydro‐1,2,3‐oxathiazine 2,2‐Dioxides and 1‐Benzyl‐4‐methylazetidines.
Authors: Varlamov A. V. , Sidorenko N. V. , Zubkov F. I. , Chernyshev A. I. , Turchin K. F. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Cleavage of C—Si Bond by Intramolecular Nucleophilic Attack: Lithiation‐Promoted Formation of Siloles from 1‐Bromo‐4‐trisubstituted Silyl‐1,3‐butadiene Derivatives.
Authors: Wang Zhihui , Fang Hongyun , Yi Zhenfeng 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Isolation of a Cyclic Intermediate in the Reaction of a Phosphorus Ylide with Elemental Sulfur: Synthesis, Structure, and Reactivity of a 1,2σ5‐Thiaphosphirane.
Authors: Sase Shohei , Kano Naokazu , Kawashima Takayuki 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Fungicidal Activity of Some 6‐Aryl‐2‐(β‐D‐glucopyranosyl)‐3‐oxo‐2,3‐dihydro‐1,3,4‐oxadiazolo [3,2‐b]‐1,2,4,6‐thiatriazine‐1,1‐dioxides.
Authors: Khare R. K. , Srivastava Alok Kumar , Singh H. 
Published: April 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Conformational and Electronic Properties of a Microperoxidase in Aqueous Solution: A Computational Study
Authors: Di Teodoro Carla , Aschi Massimiliano , Amadei Andrea , Roccatano Danilo , Malatesta Francesco , Ottaviano Luca 
Published: April 2005

AbstractA theoretical study of the conformational properties of a small heme peptide in aqueous solution is carried out by classical, long‐timescale molecular dynamics simulations. The electronic properties of this species, that is, the relative energies of its excited electronic states and the redox potential, are reproduced and related to the conformational behavior using the perturbed matrix method and basic statistical mechanics. Our results show an interesting coupling between the conformational transitions and the electronic properties. These investigations, beyond the biophysically relevant results addressing the long‐standing question of the actual role of the enzyme structure on the enzyme activity, are also of some methodological interest since they offer a further computational perspective for incuding the electronic degrees of freedom into the modeling of rather complex molecular systems.
A three‐phase constant‐current source using an immittance converter
Authors: Irie Hisaichi , Oohashi Shunsuke 
Published: April 2005

AbstractThe term immittance converter refers to an impedance–admittance converter. The immittance converter has an input impedance that is proportional to the admittance of the load connected across output terminals. In this converter, the output current is proportional to the input voltage and the input current is proportional to the output voltage. Consequently, it converts a constant‐voltage source into a constant‐current source and a constant‐current source into a constant‐voltage source.It is well known that the quarter wavelength transmission line shows immittance conversion characteristics. However, it has a very long line length for the switching frequency, and is not suitable for power electronics applications. We thus proposed immittance converters that consist of lumped elementsL,Cand show improved immittance conversion characteristics at a resonant frequency.A three‐phase constant‐current source is proposed in this paper. It is possible to realize this by a simple circuit using an immittance converter. In this paper, circuit operation, characteristic equations, and results of simulation are described. © 2005 Wiley Periodicals, Inc. Electr Eng Jpn, 151(4): 47–54, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/eej.20078
Development of a process for producing high‐purity calcium carbonate (CaCO3) from waste cement using pressurized CO2
Authors: Katsuyama Yasuro , Yamasaki Akihiro , Iizuka Atsushi , Fujii Minoru , Kumagai Kazukiyo , Yanagisawa Yukio 
Published: April 2005

AbstractA new type of process for producing high‐purity calcium carbonate from waste cement powder was developed. The process consists of two main reactions; extraction of calcium in the form of calcium ions from waste cement powder in a water slurry by pressurized CO2 (typically at several MPa), and precipitation of calcium carbonate (CaCO3) from the extracted solution by reduction of the CO2 pressure. The process can be recognized as the emission reduction process of CO2 as well. Laboratory‐scale experimental studies were conducted for both the extraction reaction and the precipitation reaction, to examine the feasibility of the process. The extraction process was found to proceed at a relatively high rate, especially during the initial 10 min. The concentration of calcium ions exceeded the thermodynamic solubility of CaCO3 (supersaturation) when abundant waste cement was available. After filtration of the residues, CaCO3 particles with >98% purity were obtained by depressurizing the CO2. The dependency of the reaction rates on the operating conditions, such as the ratio of waste cement to water, CO2 pressure, and particle size of waste cement particles, was investigated. A process design was carried out based on the experimental results, assuming that the present process is applied to two types of CaCO3 production process: flue gas desulfurization and production of ultrahigh‐purity CaCO3. The estimated costs per 1 metric ton of CaCO3 were USD 136 for desulfurization and USD 323 for high‐purity CaCO3. © 2005 American Institute of Chemical Engineers Environ Prog, 2005
Involvement of microtubules and Rho pathway in TGF‐β1‐induced lung vascular barrier dysfunction
Authors: Birukova Anna A. , Birukov Konstantin G. , Adyshev Djanibek , Usatyuk Peter , Natarajan Viswanathan , Garcia Joe G.N. , Verin Alexander D. 
Published: April 2005

AbstractTransforming growth factor‐β1 (TGF‐β1) is a cytokine critically involved in acute lung injury and endothelial cell (EC) barrier dysfunction. We have studied TGF‐β1‐mediated signaling pathways and examined a role of microtubule (MT) dynamics in TGF‐β1‐induced actin cytoskeletal remodeling and EC barrier dysfunction. TGF‐β1 (0.1–50 ng/ml) induced dose‐dependent decrease in transendothelial electrical resistance (TER) in bovine pulmonary ECs, which was linked to increased actin stress fiber formation, myosin light chain (MLC) phosphorylation, EC retraction, and gap formation. Inhibitor of TGF‐β1 receptor kinase RI (5 μM) abolished TGF‐β1‐induced TER decline, whereas inhibitor of caspase‐3 zVAD (10 μM) was without effect. TGF‐β1‐induced EC barrier dysfunction was linked to partial dissolution of peripheral MT meshwork and decreased levels of stable (acetylated) MT pool, whereas MT stabilization by taxol (5 μM) attenuated TGF‐β1‐induced barrier dysfunction and actin remodeling. TGF‐β1 induced sustained activation of small GTPase Rho and its effector Rho‐kinase; phosphorylation of myosin binding subunit of myosin specific phosphatase; MLC phosphorylation; EC contraction; and gap formation, which was abolished by inhibition of Rho and Rho‐kinase, and by MT stabilization with taxol. Finally, elevation of intracellular cAMP induced by forskolin (50 μM) attenuated TGF‐β1‐induced barrier dysfunction, MLC phosphorylation, and protected the MT peripheral network. These results suggest a novel role for MT dynamics in the TGF‐β1‐mediated Rho regulation, EC barrier dysfunction, and actin remodeling. © 2005 Wiley‐Liss, Inc.
CpG‐oligodeoxynucleotides induce mobilization of hematopoietic progenitor cells into peripheral blood in association with mouse KC (IL‐8) production
Authors: Nardini Elena , Morelli Daniele , Aiello Piera , Besusso Dario , Calcaterra Claudia , Mariani Luigi , Palazzo Marco , Vecchi Annunciata , Paltrinieri Saverio , Menard Sylvie , Balsari Andrea 
Published: April 2005

AbstractThe immune system of vertebrates detects bacterial DNA as a “danger signal” based on the presence of unmethylated CpG motifs. We examined whether oligodeoxynucleotides (ODNs) with CpG motifs (CpG‐ODNs) also induce mobilization of hematopoietic progenitor cells (HPCs). Mice challenged with CpG‐ODNs showed an increase in peripheral blood colony‐forming units (CFU) with a peak at day 4 after treatment, associated with an increase, starting 30 min after CpG treatment, in serum levels of mouse keratinocyte‐derived chemokine (mKC), a functional homolog of human interleukin (IL) 8; production of granulocyte‐colony‐stimulating factor (CSF) was also detected. Mobilization and mKC induction were sequence‐specific and dose‐dependent occurring even with low doses of CpG‐ODNs. Interestingly, intestinal cells were involved in mKC production. HPC mobilization by CpG‐ODNs was dependent on peripheral blood mononuclear cells since mobilization was reduced in neutrophil‐depleted mice. Moreover, CpG‐ODN treatment significantly increased G‐CSF mobilizing capacity. Finally, pretreatment with an anti‐mKC neutralizing antibody significantly reduced CpG‐induced mobilization, further supporting a role for mKC. Thus, bacterial DNA is a “danger signal” not only for immune cells but also for hematopoietic cells, communicating the need for increased hematopoiesis during infections and for the renewal of the immune system. The HPC mobilization activity of CpG‐ODNs will need to be considered in the design of treatment regimens for cancer clinical trials using CpG‐ODNs in association with chemotherapy. © 2005 Wiley‐Liss, Inc.
Ornithine‐urea cycle and urea synthesis in African lungfishes, Protopterus aethiopicus and Protopterus annectens, exposed to terrestrial conditions for six days
Authors: Loong Ai May , Hiong Kum Chew , Lee Serene Min Lin , Wong Wai Peng , Chew Shit Fun , Ip Yuen Kwong 
Published: April 2005

AbstractThe objectives of this study were (1) to determine the type of carbamoyl phosphate synthetase (CPS) present, and the compartmentalization of arginase, in the livers of the African lungfishes, Protopterus aethiopicus and Protopterus annectens, and (2) to elucidate if these two lungfishes were capable of increasing the rates of urea synthesis and capacities of the ornithine‐urea cycle (OUC) during 6 days of aerial exposure without undergoing aestivation. Like another African lungfish, Protopterus dolloi, reported elsewhere, the CPS activities from the livers of P. aethiopicus and P. annectens had properties similar to that of the marine ray (Taeniura lymma), but dissimilar to that of the mouse (Mus musculus). Hence, they possessed CPS III, and not CPS I as reported previously. CPS III was present exclusively in the liver mitochondria of both lungfishes, but the majority of the arginase activities were present in the cytosolic fractions of their livers. Glutamine synthetase (GS) activity was also detected in the hepatic mitochondria of both specimens. Therefore, our results suggest that the evolution of CPS III to CPS I might not have occurred before the evolution of extant lungfishes as suggested previously, prompting an examination of the current view on the evolution of CPS and OUC in vertebrates. Aerial exposure led to significant decreases in rates of ammonia excretion in P. aethiopicus and P. annectens, but there were no accumulations of ammonia in their tissues. However, urea contents in their tissues increased significantly after 6 days of aerial exposure. The estimated rates of urea synthesis in P. aethiopicus and P. annectens increased 1.2‐ and 1.47‐fold, respectively, which were smaller than that in P. dolloi (8.6‐fold) reported elsewhere. In addition, unlike P. dolloi, 6 days of aerial exposure had no significant effects on the hepatic CPS III activities of P. aethiopicus and P. annectens. In contrast, aerial exposure induced relatively greater degrees of reductions in ammonia production in P. aethiopicus (34%) and P. annectens (37%) than P. dolloi (28%) as previously reported. Thus, our results suggest that various species of African lungfishes respond to aerial exposure differently with respect to nitrogen metabolism and excretion, and it can be concluded that P. aethiopicus and P. annectens depended more on reductions in ammonia production than on increases in urea synthesis to ameliorate ammonia toxicity when exposed to terrestrial conditions. J. Exp. Zool. 303A:354–365, 2005. © 2005 Wiley‐Liss, Inc.
Direct evidence of interaction between dislocations and point defects in diamond
Authors: Mora A. E. , Steeds J. W. , Butler J. E. , Yan C.‐S. , Mao H. K. , Hemley R. J. 
Published: April 2005

AbstractThe detailed correlation of results from two dissimilar experimental techniques, transmission electron microscopy and micro‐photoluminescence spectroscopy, has allowed us to obtain direct evidence of the interaction between linear and point defects in diamond as both 388.9 nm and 379 nm optical centers were found to be strongly related to dislocations. (© 2005 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)