bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scenographies of Waiting
Authors: Garrison John S. 
Published: October 2023

AbstractThis chapter explores the ways in which the speaker promises he can function as a double for the beloved, either in terms of the early modern friendship model or in terms of marriage. The poet draws upon a variety of dyadic models that promise pleasure, yet the power dynamics inherent in race and sexuality call that promise into question. The chapter draws upon psychoanalysis to consider idealized friends and married partners in Sonnet 122, Sonnet 24, Sonnet 73, Sonnet 74, as well as the master and the enslaved person in Sonnet 57 and Sonnet 58. Examining these poems along with Sonnet 43 yields a discussion that finds that each sonnet variously undermines the promise of the double to store and to carry forward memories as the speaker waits for the beloved.
Remembering, Repeating, and Writing Through
Authors: Garrison John S. 
Published: October 2023

AbstractThis chapter adapts its title from Freud’s early essay on the repetition compulsion and explores a question that has vexed many readers: why does repetition abound in the Sonnets, both within certain key poems and across the poems? This chapter argues for repetition as a form of erotic memory, revealing that this persistent rhetorical technique emphasizes that recollected pleasure intensifies with each instance. The chapter opens with an analysis of Sonnet 76 to explore how memory becomes unreliable when reliant on a network of minds. The argument then focuses on Sonnet 35 as well as a contemporary adaptation of it by Cedar Sigo to explore the pleasure inherent in toxic or bad memories. Further discussion of Sonnet 53 and Sonnet 55, as well as Sonnet 71 and Sonnet 72, considers how insights into forgetting from cognitive science and psychoanalysis grant new insight into Shakespeare’s poems.
The First Fiscal State Aid Wave
Authors: Kyriazis Dimitrios 
Published: October 2023

AbstractThis chapter analyses how the Commission started using State aid law as a tool against harmful tax competition in the early 2000s. It is divided into four parts. Section A introduces the key elements of the chapter. In Section B, the Commission’s relevant decision-making practice is scrutinized, mainly by focusing on five key Commission decisions and presenting their factual and legal background in order to demonstrate how effective State aid policy can be in the fight against harmful tax competition. In Section C, the Commission’s decisions’ common threads are identified and assessed. Finally, in Section D, the landmark Gibraltar case of the ECJ is used to argue that the evolution of the selectivity condition has had the effect of making it extremely difficult for Member States to enact or preserve harmful tax measures.
Totality
Authors: Littmann Mark , Espenak Fred 
Published: October 2023

Abstract
Totality: The Great North American Eclipse of 2024offers a relaxed, well-written, and information-packed journey discovering the history of eclipses. It also provides an overview of the mysteries surrounding solar eclipses. Photographs, maps, diagrams, charts, and illustrations aim to aid readers in safely understanding and enjoying the science, history, mythology, and folklore of eclipses. Moreover, Totalitydetails tips on how to best photograph or video record an eclipse depending on its total or partial phase. It looks into detailed maps, precise locations, and weather prospects surrounding the expected eclipse on April 8, 2024, which passes across Mexico, the United States, and Canada.
Constructing Quantum Mechanics Volume Two
Authors: Janssen Michel , Duncan Anthony 
Published: October 2023

AbstractThis is the second of two volumes on the genesis of quantum mechanics in the first quarter of the twentieth century. It covers the period 1923–1927. It traces how the old quantum theory of Bohr and Sommerfeld gave way to the matrix mechanics of Heisenberg and others, and to the wave mechanics of Schrödinger. It then turns to the emergence of statistical transformation theory and the Hilbert space formalism unifying these two forms of the new quantum theory. It uses the metaphor of an arch built on a scaffold to capture these developments. The volume provides detailed analyses of the classic papers of Heisenberg, Born, Jordan, Pauli, Dirac, De Broglie, Einstein, Schrödinger, von Neumann, and others, which helped to lay the foundations of modern quantum mechanics. Drawing on correspondence and later reminiscences of these authors and synthesizing much of the extensive secondary literature on the breakthrough to modern quantum mechanics in the mid-1920s, this volume presents an authoritative new account of the genesis of quantum mechanics.
Schrödinger and Wave Mechanics
Authors: Duncan Anthony , Janssen Michel 
Published: October 2023

AbstractThis chapter explores Schrödinger’s introduction of wave mechanics. After briefly covering Schrödinger’s earlier work, it turns to the investigations that led him to write a four-part paper in 1926 introducing and applying wave mechanics. The chapter provides a detailed analysis of these four papers, in which the analogy of the new theory to the Hamilton-Jacobi formulation of classical mechanics plays a central role, as well as the paper written in between the second and the third installment on the relation between wave and matrix mechanics. The chapter also discusses Schr "odinger’s original interpretation of his wave functions and the reception of his theory by the physics community.
Oxford personnel
Authors: Aston Nigel 
Published: October 2023

Abstract
Chapter 6 is the first of four denoted by themes of institutional presence and interaction. This one looks at University office-holders and their relations to the polity and politics of Hanoverian Britain. The careers of all the Chancellors and some of the Vice Chancellors are treated, as well as selective college and hall heads and senior tutors. Their laxity could inflict serious damage on the institution, especially struggling for tokens of official favour under the first two Georges. Their influence reached a climax in the 1790s with Cyril Jackson, Dean of Christ Church, university reformer and close to Pitt the Younger’s wartime administration. The chapter also considers those with formal roles and power inside the University (the college Visitors and successive Bishops of Oxford before 1836). All these, stood in the centre of intersecting patronage networks, and exercised political influence in and beyond the University.
Oxford and the wider world
Authors: Aston Nigel 
Published: October 2023

Abstract
Oxford was not primarily a centre of unqualified endorsement for progressive thinking. It was rather one for an admixture of ideas, both ‘ancient’ and ‘modern’, and compared favourably with its European academic counterparts. The interaction of Oxford graduates with their counterparts in continental Europe could give a flattering impression of the University’s part in their social fashioning, but Oxford dons were generally welcomed in libraries and academies across Europe irrespective of confessional divergences, and were participants in a trans-European Republic of Letters. And Continental scholars travelled to Oxford to use its libraries and teach, a few matriculating as members of the University. Guests and hosts alike shared in the common culture of eighteenth-century elites, rooted in Antiquity, and enriched in the Renaissance. The chapter also examines imperial connections that linked Oxford to British North America, and the ways in which the Anglo-Hanoverian union provided an important transnational framework for scholarly exchanges.
Fertile Crescent to Frankfurt
Authors: Bamforth Charles W. 
Published: October 2023

Abstract
Beer is brewed and consumed worldwide. This chapter digs deep into the nature of the current world of beer: How do countries compare in terms of their beer production and consumption? How does beer consumption relate to that of wine and hard liquor, and what are the driving forces for differences, such as taxation? How do the states within the United States differ in beer consumption and taxation? The chapter describes the trajectory of the craft brewing scene in the United States, including how a craft beer is defined. Which are the biggest brewing companies in the world and the most successful brands?
A Brief History of Beer
Authors: Bamforth Charles W. 
Published: October 2023

Abstract
Beer has been a feature of society for some 8,000 years. It has been argued that brewing was a fundamental driving force for the shift from a nomadic to a static, agriculture-based society. Beer has been successively a societal norm in cultures from the Sumerians, through the Egyptians, to the monasteries of medieval Europe and on to today’s craft-driven businesses. There is an intertwining of beer and religion! The British and German brewing histories serve to illustrate well the driving forces that dictate the shape of brewing to this day. And both nations influenced the direction taken by the brewing industry in the United States, which has featured the growth of enormous brewing companies despite the ravages of prohibition. Scientists working within the brewing industry over the past 1.5 centuries have made major contributions not only to improvements in brewing operations, but also in ways applicable far more widely in society (e.g., the concept of pH).
Personal Choice
Authors: Bamforth Charles W. 
Published: October 2023

Abstract
There are endless beer styles, and these are captured here. Fundamentally, most beers can be divided into ales and lagers, the former being fermented using the yeast Saccharomyces cerevisiae and the latter with Saccharomyces pastorianus. Generally, ales are fermented at higher temperatures than lagers. In each category there are diverse types. Included in the ales are pale ales, India pale ales, milds, porters, stouts, wheat beers, barley wines, sour beers, and Trappist ales. There are also beers such as Kölsch which employ ale yeast but are produced as if they are lagers. Lagers include pilsners, marzens, bocks, helles, dunkels, and more. Again, there is a “hybrid,” with lager yeast being used at warmer fermentation and maturation temperatures, the so-called California Common. Beers may also be classified according to functionality or process, including products such as light beers, ice beers, dry beers, non-alcoholic beers, and those mixed with fruits and spices.
The Wicked and Pernicious Weed
Authors: Bamforth Charles W. 
Published: October 2023

Abstract
Although there remain some beers that are flavored with mixes of herbs and spices (gruit), most beers include hops that provide bitterness (from the resins) and aroma (from the oils). Hops are the flowering bodies from female plants of Humulus lupulus, the closest botanical relative of which is marijuana. Some brewers insist on using these hop cones, but increasingly there is use of hop products such as pellets and extracts, from which the key components can be extracted more readily. There is a diversity of hop varieties, differing in their content of resins and oils, and in the nature of the aroma derived from the latter. Different hops provide aromas that can be variously characterized as spicy, floral, fruity, herbal, citrus, and piney.
Hot Stuff
Authors: Bamforth Charles W. 
Published: October 2023

Abstract
The operations involved in the brewing of beer can be divided into a hot side, the brewhouse, and a cold side, fermentation and maturation. The malt entering the brewery is milled into small particles, which are then mixed with hot water. In this mashing stage the primary event is the breakdown of starch into fermentable sugars catalyzed by enzymes called amylases. By regulating the temperature, brewers can ensure that they get the degree of fermentability required in each wort. The liquid produced (wort) is then separated from the residual solids (spent grains) and boiled with hops. In this stage the bitterness is extracted from the hops, there is a precipitation of undesirable materials (trub), a sterilization of the wort, and an evaporation of water and undesirable aromas. Thereafter the insoluble materials are removed, usually by centripetal forces in a vessel called a whirlpool, prior to the wort being cooled and ready for fermentation.
Refining Matters
Authors: Bamforth Charles W. 
Published: October 2023

Abstract
Beer leaving the fermenter requires some element of further processing prior to packaging. Traditionalists, particularly brewers making lagers, insist that there must be a relatively prolonged maturation period, though this is questioned. Irrespective of the length of storage, mist beers are chilled to as cold a temperature as possible without freezing, to precipitate unwanted materials. Frequently they are clarified by filtration or centrifugation and may be stabilized by removing unwanted entities such as polyphenols and certain proteins. There is also usually a need to adjust the carbon dioxide level to that needed for a given product. Unwanted microorganisms may be eliminated either by further filtration or pasteurization. Other than for beers to be served at the location where the beer is brewed, most beer is either filled into kegs for draft dispense, or into bottles and, increasingly, cans. These are complex and expensive operations.
Identification of PANoptosis-related biomarkers and immune infiltration characteristics in psoriasis
Authors: Lu Lingling , Zhang Buxin , Shi Meiling , Liu Aimin 
Published: October 2023

Background:
PANoptosis may play a vital role in psoriasis. We investigated the relationship between PANoptosis in psoriasis.

Methods:
Genes information was mainly obtained from GeneCards and the gene expression omnibus database. Genefunctions identification was based on gene ontology and Kyoto Encyclopedia of Genes and Genomes analyses. Gene set enrichment analysis was used to identify enriched signaling pathways in psoriasis. We constructed PPI networks using the search tool for the retrieval of interacting genes database and Cytoscape and explored mRNA-miRNA, mRNA-TF, and mRNA-drug interaction networks. Receiver operating characteristic curves were performed to screen potential biomarkers among these hub genes. Immune cell infiltration was analyzed using the Pearson algorithm, and the correlation between immune-cell abundance and PANoptosis-related differentially expressed gene (PDGs) was investigated.

Results:
We identified 10 PDGs, which were mainly involved in pyroptosis, cytokine-mediated signaling pathways, Salmonella infection and NOD-like receptor signaling pathway. The activated pathways were mostly proinflammatory and immunoregulatory pathways between immune cells. BAK1, CASP4, IL18, and IRF1 were identified as hub genes in the mRNA-miRNA network, and BAK1, IRF1, and PYCARD were hub genes in the mRNA-TF network. CASP1 was found to be the most targeted gene by drugs or molecular compounds. We found PDGs were positively associated with proinflammatory immune cell infiltration and negatively associated with anti-inflammatory or regulatory immune cells.

Conclusion:
We confirmed the role of PANoptosis in psoriasis for the first time and predicted hub genes and immune characteristics, which provides new ideas for further investigation of psoriasis on pathogenic mechanisms and therapeutic strategies.
Posttraumatic pneumonia exacerbates bone marrow erythropoietic dysfunction
Authors: Gillies Gwendolyn S. , Munley Jennifer A. , Kelly Lauren S. , Kirkpatrick Stacey L. , Pons Erick E. , Kannan Kolenkode B. , Bible Letitia E. , Efron Philip A. , Mohr Alicia M. 
Published: October 2023

INTRODUCTION
Pneumonia is a common complication after severe trauma that is associated with worse outcomes with increased mortality. Critically ill trauma patients also have persistent inflammation and bone marrow dysfunction that manifests as persistent anemia. Terminal erythropoiesis, which occurs in bone marrow structures called erythroblastic islands (EBIs), has been shown to be impacted by trauma. Using a preclinical model of polytrauma (PT) and pneumonia, we sought to determine the effect of infection on bone marrow dysfunction and terminal erythropoiesis.

METHODS
Male and female Sprague-Dawley rats aged 9 to 11 weeks were subjected to either PT (lung contusion, hemorrhagic shock, cecectomy, and bifemoral pseudofracture) or PT with postinjury day 1 Pseudomonas pneumonia (PT-PNA) and compared with a naive cohort. Erythroblastic islands were isolated from bone marrow samples and imaged via confocal microscopy. Hemoglobin, early bone marrow erythroid progenitors, erythroid cells/EBI, and % reticulocytes/EBI were measured on day 7. Significance was defined as p < 0.05.

RESULTS
Day 7 hemoglobin was significantly lower in both PT and PT-PNA groups compared with naive (10.8 ± 0.6 and 10.9 ± 0.7 vs. 12.1 ± 0.7 g/dL [p < 0.05]). Growth of bone marrow early erythroid progenitors (colony-forming units—granulocyte, erythrocyte, monocyte, megakaryocyte; erythroid burst-forming unit; and erythroid colony-forming unit) on day 7 was significantly reduced in PT-PNA compared with both PT and naive. Despite a peripheral reticulocytosis following PT and PT-PNA, the percentage of reticulocytes/EBI was not different between naive, PT, and PT-PNA. However, the number of erythroblasts/EBI was significantly lower in PT-PNA compared with naive (2.9 ± 1.5 [p < 0.05] vs. 8.9 ± 1.1 cells/EBI macrophage). In addition to changes in EBI composition, EBIs were also found to have significant structural changes following PT and PT-PNA.

CONCLUSION
Multicompartmental PT altered late-stage erythropoiesis, and these changes were augmented with the addition of pneumonia. To improve outcomes following trauma and pneumonia, we need to better understand how alterations in EBI structure and function impact persistent bone marrow dysfunction and anemia.
Deep learning-based aberration compensation improves contrast and resolution in fluorescence microscopy
Authors: Guo Min , Wu Yicong , Hobson Chad M. , Su Yijun , Qian Shuhao , Krueger Eric , Christensen Ryan , Kroeschell Grant , Bui Johnny , Chaw Matthew , Zhang Lixia , Liu Jiamin , Hou Xuekai , Han Xiaofei , Lu Zhiye , Ma Xuefei , Zhovmer Alexander , Combs Christian , Moyle Mark , Yemini Eviatar , Liu Huafeng , Liu Zhiyi , Benedetto Alexandre , La Riviere Patrick , Colón-Ramos Daniel , Shroff Hari 
Published: October 2023

AbstractOptical aberrations hinder fluorescence microscopy of thick samples, reducing image signal, contrast, and resolution. Here we introduce a deep learning-based strategy for aberration compensation, improving image quality without slowing image acquisition, applying additional dose, or introducing more optics into the imaging path. Our method (i) introduces synthetic aberrations to images acquired on the shallow side of image stacks, making them resemble those acquired deeper into the volume and (ii) trains neural networks to reverse the effect of these aberrations. We use simulations and experiments to show that applying the trained ‘de-aberration’ networks outperforms alternative methods, providing restoration on par with adaptive optics techniques; and subsequently apply the networks to diverse datasets captured with confocal, light-sheet, multi-photon, and super-resolution microscopy. In all cases, the improved quality of the restored data facilitates qualitative image inspection and improves downstream image quantitation, including orientational analysis of blood vessels in mouse tissue and improved membrane and nuclear segmentation inC. elegansembryos.
Global control of cellular physiology by biomolecular condensates through modulation of electrochemical equilibria
Authors: Dai Yifan , Zhou Zhengqing , Kim Kyeri , Rivera Nelson , Mohammed Javid , Hsu-Kim Heileen , Chilkoti Ashutosh , You Lingchong 
Published: October 2023

AbstractControl of the electrochemical environment in living cells is typically attributed to ion channels. Here we show that the formation of biomolecular condensates can modulate the electrochemical environment in cells, which affects processes globally within the cell and interactions of the cell with its environment. Condensate formation results in the depletion or enrichment of certain ions, generating intracellular ion gradients. These gradients directly affect the electrochemical properties of a cell, including the cytoplasmic pH and hyperpolarization of the membrane potential. The modulation of the electrochemical equilibria between the intra- and extra-cellular environments by biomolecular condensates governs charge-dependent uptake of small molecules by cells, and thereby directly influences bacterial survival under antibiotic stress. The shift of the intracellular electrochemical equilibria by condensate formation also drives a global change of the gene expression profile. The control of the cytoplasmic environment by condensates is correlated with their volume fraction, which can be highly variable between cells due to the stochastic nature of gene expression at the single cell level. Thus, condensate formation can amplify cell-cell variability of the environmental effects induced by the shift of cellular electrochemical equilibria. Our work reveals new biochemical functions of condensates, which extend beyond the biomolecules driving and participating in condensate formation, and uncovers a new role of biomolecular condensates in cellular regulation.
Examining the relationships between big data analytics capability, entrepreneurial orientation and sustainable supply chain performance: moderating role of trust
Authors: Tipu Syed Awais Ahmad , Fantazy Kamel 
Published: October 2023

PurposeUsing a dynamic capability view, this study examined the relationships between big data analytics capability (BDAC), entrepreneurial orientation (EO) and sustainable supply chain performance (SSCP) by exploring the moderating role of trust among supply chain partners.Design/methodology/approachQuestionnaires were collected from 300 manufacturing organizations using snow sampling. The moderating connections and direct relationships were examined using Hays' process macro and structural equation modeling.FindingsBDAC was positively related to EO and SSCP. When supply chain partners experienced low levels of trust, an increase in BDAC did not enhance SSCP. As trust increased, the relationship between BDAC and SSCP became more positive, underpinning the moderating effects of trust. Moreover, trust did not moderate the relationship between BDAC and EO. The moderating effect of trust on the relationship between EO and SSCP showed a positive relationship between EO and SSCP when trust was low; however, the relationship became negative when trust was high.Practical implicationsDeveloping technology alone may not be sufficient, as supply chain managers need to establish a strong business relationship based on mutual trust. However, they also need to be aware of the dangers of high levels of trust because these may negatively affect performance. Therefore, supply chain managers need to achieve an optimal level of trust that is neither excessive nor insufficient.Originality/valueAdvances in technology and entrepreneurial drive for supply chain sustainability make it pertinent to examine trust levels among supply chain partners and the varying impact on BDAC, EO and SSCP. The current study shows the negative aspects of too much trust among supply chain partners.