bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating hydro and wind resources for effective congestion management in a hybrid electricity market
Authors: Reddy Ch. Lokeshwar , Rayudu K. , Sharanya M. , Patthi Sridhar , Rao J. V. G. Rama 
Published: December 2023

AbstractCongestion management in deregulated electricity systems threatens system security and reliability. Integration of renewable energy sources, unpredictable wind power, load demand, and the requirement for quickly deployable reserves make congestion management more difficult. While deciding the dispatch of the generating units, many factors have to be considered for the economic, secure, and reliable operation of the power system. This study presents a congestion management strategy that has been developed specifically for hybrid power systems. Within a pool and bilateral power supply market structure, it introduces a generator rescheduling-based congestion management technique. Ensuring safe bilateral transactions between these companies is crucial. Renewable sources affect congestion management dynamics, according to the research. The optimization issue includes operational limitations for scenarios with and without renewable source units. Monte Carlo simulation (MCS) was used to sample hourly wind speed from the Weibull PDF wind model. GAMS CONOPT solver used the model. General Algebraic Modeling System (GAMS)-MATLAB interface imported the model into MATLAB to extract the response. The best combination of renewable sources is 2 hydro + 1 wind unit as savings of congestion cost are $1403.6/h and $1855.18/h in case 1 (3-line congestion) and case 2 (2-line congestion), respectively. Results were accomplished by updating the IEEE-24 bus reliability test system with hydro and wind generators.
Stabilization of oil/water emulsions using soybean lecithin as a biobased surfactant for enhanced oil recovery
Authors: Tabaniag Jalliah Sharelle U. , Abad Mary Quincy D. , Morcelos Christian Jules R. , Geraldino Gene Vincent B. , Alvarado Jon Larsen M. , Lopez Edgar Clyde R. 
Published: December 2023

AbstractEnhanced oil recovery (EOR) relies on the use of surfactant to flood the wellbore and thus extract the oil from the rocks. However, current surfactants used for EOR are non-biodegradable and are made from toxic chemicals. Here, we report the potential of soybean lecithin as a biobased surfactant for enhancing oil recovery by stabilizing oil-in-water (O/W) emulsions. Our findings show that pH has a significant impact on stability, with lower pH levels leading to improved stability. Salinity affects stability, but soybean lecithin shows minimal sensitivity to salt concentration. Surfactant loading also plays a crucial role, with higher concentrations causing instability. The optimized operating parameters for soybean lecithin are determined to be at pH = 4, salinity = 84,171.08 ppm, and surfactant loading = 4.48 wt.%. Comparative evaluation reveals that soybean lecithin performs competitively, outperforming certain commercial surfactants in terms of emulsion stability in oil phase. The solubilization ratio of oil (SRo) values are lecithin = 3.2219, CAPB = 0.7028, CTAC = 11.1044, NP10EO = 11.1570, and SLES = 11.7067. Utilizing soybean lecithin as a biobased surfactant in enhanced oil recovery offers a sustainable and environmentally friendly alternative with potential economic advantages. Further research can focus on optimizing formulation and exploring synergies with other additives.
Molecular characterization of blaNDM-harboring plasmids reveal its rapid adaptation and evolution in the Enterobacteriaceae
Authors: Li Yiming , Yang Yuying , Wang Yifei , Walsh Timothy R. , Wang Shaolin , Cai Chang 
Published: December 2023

AbstractCarbapenem is one of the few available drugs to treat multidrug-resistance Gram-negative bacteria infections. Recently, the plasmid-mediated spread of the carbapenem resistance gene blaNDM poses a significant threat to public health, requiring global monitoring and surveillance. Here, we used both short-read (n = 2461) and long-read (n = 546) sequencing data to characterize the global distribution of blaNDM. We analyzed the replicon type of blaNDM-positive plasmids and found that the dominant plasmid type was different in diverse geographical locations. Although blaNDM gene has been transferred across diverse countries, its genetic backgrounds are highly conserved, and the mobile genetic element ISAba125, IS5, and IS26 may play an important role in the mobilization of blaNDM. A significant association was observed between host origin and gene presence/deletion variation on IncX3 plasmid, which may be a key factor in the bacterial adaption to diverse hosts. In this study, we analyzed the diversity, distribution and transmission of blaNDM-positive plasmids from a global perspective, and emphasize the importance of plasmid analysis for understanding the evolution and adaptation of blaNDM-positive plasmids and their co-evolution with bacterial genomes (resistome).
Obesity Variants in the GIPR Gene Are not Associated With Risk of Fracture or Bone Mineral Density
Authors: Styrkarsdottir Unnur , Tragante Vinicius , Stefansdottir Lilja , Thorleifsson Gudmar , Oddsson Asmundur , Sørensen Erik , Erikstrup Christian , Schwarz Peter , Jørgensen Henrik Løvendahl , Lauritzen Jes Bruun , Brunak Søren , Knowlton Kirk U , Nadauld Lincoln D , Ullum Henrik , Pedersen Ole Birger Vesterager , Ostrowski Sisse Rye , Holm Hilma , Gudbjartsson Daniel F , Sulem Patrick , Stefansson Kari 
Published: December 2023

Abstract

Context
It is not clear if antagonizing the GIP (glucose-dependent insulinotropic polypeptide) receptor (GIPR) for treatment of obesity is likely to increase the risk of fractures, or to lower bone mineral density (BMD) beyond what is expected with rapid weight loss.

Objective
The objective of this study was to investigate the risk of fracture and BMD of sequence variants in GIPR that reduce the activity of the GIP receptor and have been associated with reduced body mass index (BMI).

Methods
We analyzed the association of 3 missense variants in GIPR, a common variant, rs1800437 (p.Glu354Gln), and 2 rare variants, rs139215588 (p.Arg190Gln) and rs143430880 (p.Glu288Gly), as well as a burden of predicted loss-of-function (LoF) variants with risk of fracture and with BMD in a large meta-analysis of up to 1.2 million participants. We analyzed associations with fractures at different skeletal sites in the general population: any fractures, hip fractures, vertebral fractures and forearm fractures, and specifically nonvertebral and osteoporotic fractures in postmenopausal women. We also evaluated associations with BMD at the lumbar spine, femoral neck, and total body measured with dual-energy x-ray absorptiometry (DXA), and with BMD estimated from heel ultrasound (eBMD).

Results
None of the 3 missense variants in GIPR was significantly associated with increased risk of fractures or with lower BMD. Burden of LoF variants in GIPR was not associated with fractures or with BMD measured with clinically validated DXA, but was associated with eBMD.

Conclusion
Missense variants in GIPR, or burden of LoF variants in the gene, are not associated with risk of fractures or with lower BMD.
Gynecomastia in a Man With Adrenal Mass
Authors: Saini Jasmine , Navin Patrick , Rivera Michael , Bancos Irina 
Published: December 2023

Abstract
Estrogen-secreting adrenocortical carcinoma (ACC) is exceedingly rare, representing 1% to 2% of all ACCs. We present a case of a 65-year-old man diagnosed with an estrogen-secreting, 4.3-cm right adrenal mass discovered during work-up for bilateral gynecomastia. Gynecomastia and hyperestrogenism resolved after laparoscopic adrenalectomy, and pathology was reported as adrenocortical adenoma. However, 5 years later, he again developed bilateral gynecomastia because of recurrent hyperestrogenism. Imaging revealed multiple metastases in the abdomen. Urine steroid profiling demonstrated increased androgen precursors, androgen metabolites, and glucocorticoid precursors. Ultrasound-guided biopsy of one of the metastases confirmed ACC. Initial therapy included debulking surgery with removal of metastatic lesions. Mitotane therapy was initiated 4 weeks later along with hydrocortisone for anticipated mitotane-induced adrenal insufficiency. Histopathology from the adrenalectomy specimen 5 years earlier was rereviewed and confirmed ACC. Estrogen-secreting adrenal tumors are exceedingly rare, and the majority are malignant. This case underlines the importance of making an initial accurate diagnosis of adrenal malignancy that allows better surgical planning and appropriate monitoring. Indeterminate imaging characteristics of the adrenal mass, as well as the presentation with estrogen excess, suggested an elevated risk for ACC. Initial pathology-based misdiagnosis illustrates the need for an expert adrenal pathologist to review these rare tumors.
Ventriculoatrial Shunt Versus Ventriculoperitoneal Shunt: A Systematic Review and Meta-Analysis
Authors: Oliveira Leonardo de Barros , Hakim Fernando , Semione Gabriel da Silva , Bertani Raphael , Batista Sávio , Palavani Lucca B. , Sousa Marcelo Porto , Gómez-Amarillo Diego F. , Mejía-Michelsen Isabella , Pinto Fernando Campos Gomes , Rabelo Nicollas Nunes , Welling Leonardo C. , Figueiredo Eberval Gadelha 
Published: December 2023

BACKGROUND AND OBJECTIVES:
Ventriculoperitoneal shunt (VPS) is usually the primary choice for cerebrospinal fluid shunting for most neurosurgeons, while ventriculoatrial shunt (VAS) is a second-line procedure because of historical complications. Remarkably, there is no robust evidence claiming the superiority of VPS over VAS. Thus, we aimed to compare both procedures through a meta-analysis.

METHODS:
Following Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines, the authors systematically searched the literature for articles comparing VAS with VPS. The included articles had to detail one of the following outcomes: revisions, infections, shunt-related mortality, or complications. In addition, the cohort for each shunt model had to encompass more than 4 patients.

RESULTS:
Of 1872 articles, 16 met our criteria, involving 4304 patients, with 1619 undergoing VAS and 2685 receiving VPS placement. Analysis of revision surgeries showed no significant difference between VAS and VPS (risk ratio [RR] = 1.10, 95% CI: 0.9-1.34; I2 = 84%, random effects). Regarding infections, the analysis also found no significant difference between the groups (RR = 0.67, 95% CI: 0.36-1.25; I2 = 74%, random effects). There was no statistically significant disparity between both methods concerning shunt-related deaths (RR = 2.11, 95% CI: 0.68-6.60; I2 = 56%, random effects). Included studies after 2000 showed no VAS led to cardiopulmonary complications, and only 1 shunt-related death could be identified.

CONCLUSION:
Both methods show no significant differences in procedure revisions, infections, and shunt-related mortality. The literature is outdated, research in adults is lacking, and future randomized studies are crucial to understand the profile of VAS when comparing it with VPS. The final decision on which distal site for cerebrospinal shunting to use should be based on the patient's characteristics and the surgeon's expertise.
Circulating Plasma Oxytocin Level Is Elevated by High-Intensity Interval Exercise in Men
Authors: TSUKAMOTO HAYATO , OLESEN NIELS D. , PETERSEN LONNIE G. , SUGA TADASHI , SØRENSEN HENRIK , NIELSEN HENNING B. , OGOH SHIGEHIKO , SECHER NIELS H. , HASHIMOTO TAKESHI 
Published: December 2023

ABSTRACT

Purpose
We evaluated whether repeated high-intensity interval exercise (HIIE) influences plasma oxytocin (OT) concentration in healthy men, and, given that OT is mainly synthesized in the hypothalamus, we assessed the concentration difference between the arterial (OTART) versus the internal jugular venous OT concentration (OTIJV). Additionally, we hypothesized that an increase in cerebral OT release and the circulating concentration would be augmented by repeated HIIE.

Methods
Fourteen healthy men (age = 24 ± 2 yr; mean ± SD) performed two identical bouts of HIIE. These HIIE bouts included a warm-up at 50%–60% maximal workload (W
max) for 5 min followed by four bouts of exercise at 80%–90% W
max for 4 min interspersed by exercise at 50%–60% W
max for 3 min. The HIIE bouts were separated by 60 min of rest. OT was evaluated in blood through radial artery and internal jugular vein catheterization.

Results
Both HIIE bouts increased both OTART (median [IQR], from 3.9 [3.4–5.4] to 5.3 [4.4–6.3] ng·mL−1 in the first HIIE, P < 0.01) and OTIJV (from 4.6 [3.4–4.8] to 5.9 [4.3–8.2] ng·mL−1, P < 0.01), but OTART-IJV was unaffected (from −0.24 [−1.16 to 1.08] to 0.04 [−0.88 to 0.78] ng·mL−1, P = 1.00). The increased OT levels were similar in the first and second HIIE bouts (OTART
P = 0.25, OTIJV
P = 0.36).

Conclusions
Despite no change in the cerebral OT release via the internal jugular vein, circulating OT increases during HIIE regardless of the accumulated exercise volume, indicating that OT may play role as one of the exerkines.
FORMATION OF EDUCATIONAL INDEPENDENCE AS A CONDITION FOR ACADEMIC PERFORMANCE
Authors: Milovanova Galina V. , Kulyashova Natalya M. , Shemyakina Elena Yu. 
Published: December 2023

Introduction. Improving the academic performance of students is one of the urgent problems of modern higher education, since academic activity is a determining indicator of the readiness of university graduates for professional activities. Academic achievement depends on many factors, among which the authors emphasize the ability and desire to study as the basis of educational independence.
The purpose of the study. The purpose of the study is to examine the degree of influence of the formation of the motivational sphere and skills of independent work, determining the educational independence, on the academic performance.
Materials and methods. The following methods were used to achieve the research objectives: questioning, testing, comparative and correlation analysis. The results were processed by methods of mathematical statistics in SPSS Statistics 26.
Results. The results obtained allow us to conclude that the formation of independent work skills has a relationship with academic performance, while strong positive relationships were identified between the indicators for all five blocks of independent work skills, as well as internal and external positive motivation. Practical recommendations on maintaining the optimal motivation of students are presented.
Practical implications. The results can be used to further investigate the factors that influence academic performance and find ways to improve it.
Conclusion. After analyzing the results, the authors concluded that the important conditions for academic performance are the formation of the structure of independent educational activities of students, as well as the leading role of their internal and external positive motivation. Higher educational achievements are possible only with high levels of formation of the structure of students’ own educational activities and their positive motivation. From here follow two main directions related to the prevention of academic failure and dropout of students: the formation of optimal ways for them to independently solve educational, and in the future, professional problems and, in addition, high positive motivation at all its hierarchical levels.
Ok, gegen Cupids Pfeil hilft keine Firewall – Sichere(s) Daten durch ganzheitlichen Kompetenzaufbau
Authors: Finster Rebecca , Kronschläger Thomas , Grogorick Linda , Robra-Bissantz Susanne 
Published: December 2023

ZusammenfassungIn einer ständig präsenten digitalen Umgebung, die Technologie als zentrales Angebot nutzt, gewinnt Online-Dating immer mehr an Popularität. Ein Großteil der jüngeren Bevölkerung hat Erfahrung damit. Doch diese Entwicklung bringt neue Herausforderungen in Bezug auf Datenschutz und Informationssicherheit mit sich. Online-Dating-Plattformen (z. B. OkCupid) und -Apps (z. B. Tinder) führen zur Entstehung von Cyberintimität und eröffnen Risiken, wie Social Engineering, bei denen Menschen beeinflusst werden, um vertrauliche Informationen preiszugeben. Diese Bedrohungen könnten nicht nur persönliche Leben beeinträchtigen, sondern auch die Sicherheit von Unternehmen gefährden. Opfer von Social Engineering könnten in der vermeintlich privaten Online-Dating-Umgebung unbeabsichtigt sensible Informationen enthüllen und dadurch Unternehmensnetzwerke gefährden. Daher ist es von großer Bedeutung, digitale Fähigkeiten in Kompetenzbereichen wie Information Security Awareness und Kommunikation zu stärken und eine kritische Herangehensweise an online geteilte Informationen zu entwickeln. Diese Untersuchung analysiert die Verbindung zwischen Informationssicherheit und Online-Dating durch eine interdisziplinäre hermeneutische Analyse. Dabei liegt der Fokus auf der Rolle von Kommunikation und anderen digitalen Kompetenzen im Kontext von Informationssicherheit und Social Engineering und verdeutlicht die Wichtigkeit von Informationssicherheit über das Berufsleben hinaus.
Knowledge, attitude, and practice of virtual consultation among outpatients at a teaching hospital in Malaysia
Authors: Liew Siaw Cheok , Pallath Vinod , Rasali Yassir , Foong Chan Choong , Hong Wei Han , Tan Maw Pin 
Published: December 2023

IntroductionDuring the coronavirus disease 2019 (COVID-19) pandemic, the use of virtual consultations has accelerated to ensure continued access to healthcare despite lockdowns and physical distancing measures. We aimed to determine the knowledge (awareness) of, attitude (acceptability) to, and practice (exposure) [KAP] of virtual consultations (VC), the demographic factors associated with poor KAP, and the correlation between the three KAP domains.MethodsA cross-sectional study, using a convenience sampling technique, was conducted from 13 September, 2021 to 28 November, 2021. We designed a 45-item VC KAP questionnaire. This was distributed to outpatient users attending cardiovascular, dermatology, geriatrics, haematology, endocrine, respiratory, gastroenterology, rheumatology, or neurology clinics at the University Malaya Medical Centre. It was completed during face-to-face, online, or telephone interviews. The data were analysed using SPSS version 24.0. Binary logistic regression was used to determine the demographic factors associated with KAP. Correlation between KAP domains was determined using Spearman’s rho (r). A p-value of <0.05 was considered statistically significant.ResultsA total of 366 questionnaires were completed. Knowledge (awareness), attitude (acceptability), and practice (exposure) were considered good in 69.7%, 80.9%, and 24.6% of participants, respectively. There were no significant relationships between age, gender, ethnicity, and duration of hospital attendance (years) with knowledge (awareness), attitude (acceptability), and practice (exposure). A moderate positive correlation was seen between knowledge (awareness) and attitude (acceptability) (Attitude total [Atotal]) (r = 0.48, p<0.001), with no significant correlation between knowledge (awareness) and practice (exposure) (r = 0.04, p = 0.45), and attitude (acceptability) (Atotal) and practice (r = 0.01, p = 0.82).ConclusionOverall, outpatient clinic users had good knowledge (awareness) of and were receptive towards VC but had poor practice (exposure). More opportunities for VC use in healthcare can increase exposure and subsequent utilisation. Interventions to increase the effectiveness of VC use should be explored in future studies.
Association between dietary omega-3 intake and coronary heart disease among American adults: The NHANES, 1999–2018
Authors: Zhao Mengjie , Xiao Mengli , Tan Qin , Ji Jinjin , Lu Fang 
Published: December 2023

Background
Omega-3 has been extensively studied for its cardiovascular disease (CVD) benefits. However, the results of this evidence are inconsistent. Therefore, in this study, dietary omega-3 intake was investigated further in relation to coronary heart disease (CHD) risk among U.S. adults.

Methods
We used data from the National Health and Nutrition Examination Survey (NHANES) database for people ages 20 years and older between 1999 and 2018 to conduct a cross-sectional survey. The Medical Condition Questionnaire (MCQ) was used to determine CHD status. We measured dietary omega-3 intake using two 24-hour dietary recall interviews. Multivariate logistic regression and subgroup analysis were used to explore the correlation between dietary omega-3 intake and CHD. The dose-response relationship between the two was analyzed with a restricted cubic spline (RCS).

Results
31,184 study subjects were included, of whom 1,604 (5.14%) were patients with CHD. By quintile (Q) of dietary omega-3 intake, after adjusting for all confounding factors, compared with Q1, when total dietary omega-3, alpha-linolenic acid (ALA), docosapentaenoic acid (DPA), eicosatetraenoic acid (ETA), eicosapentaenoic acid (EPA), and docosahexenoic acid (DHA) intake reached Q5, the odds ratio (95% confidence interval, CI) of CHD were 0.76 (0.60, 0.96), 0.73 (0.57, 0.94), 0.70 (0.54, 0.92), 0.66 (0.50, 0.85), 0.84 (0.69, 1.02), and 0.83 (0.64, 1.07), respectively, while EPA and DHA were not significantly associated with the disease (Trend p > 0.05). Intake of omega-3 and CHD were linearly related (P for nonlinear = 0.603). No significant interactions were found within subgroups except for the age group (P for interaction = 0.001). Sensitivity analysis and multivariate logistic regression results are generally in agreement.

Conclusions
Total dietary omega-3, ALA, DPA, and ETA intake were negatively associated with CHD risk. In contrast, EPA and DHA had no significant correlation with CHD.
Parts-of-Speech (PoS) Analysis and Classification of Various Text Genres
Authors: Mendhakar Akshay , H S Darshan 
Published: December 2023

AbstractNatural language processing (NLP) has made significant leaps over the past two decades due to the advancements in machine learning algorithms. Text classification is pivotal today due to a wide range of digital documents. Multiple feature classes have been proposed for classification by numerous researchers. Genre classification tasks form the basis for advanced techniques such as native language identification, readability assessment, author identification etc. These tasks are based on the linguistic composition and complexity of the text. Rather than extracting hundreds of variables, a simple premise of text classification using only the text feature of parts-of-speech (PoS) is presented here. A new dataset gathered from Project Gutenberg is highlighted in this study. PoS analysis of each text in the created dataset was carried out. Further grouping of these texts into fictional and non-fictional texts was carried out to measure their classification accuracy using the artificial neural networks (ANN) classifier. The results indicate an overall classification accuracy of 98 and 35 % for the genre and sub-genre classification, respectively. The results of the present study highlight the importance of PoS not only as an important feature for text processing but also as a sole text feature classifier for text classification.