bluuebunny/crossref_metadata_2025_split huggingface dataset:
Revolutionizing the Afterlife of EV Batteries: A Comprehensive Guide to Echelon Utilization Technologies
Authors: Wang Yinfei , Hu Fengping , Wang Yiwei , Guo Jian , Yang Zhengxin , Jiang Fangming 
Published: December 2023

AbstractIn the burgeoning new energy automobile industry, repurposing retired power batteries stands out as a sustainable solution to environmental and energy challenges. This paper comprehensively examines crucial technologies involved in optimizing the reuse of batteries, spanning from disassembly techniques to safety management systems. The review assesses the viability of retired batteries, comparing their performance with that of new units, and evaluates scenarios for echelon utilization. Early safety warning systems based on temperature, voltage, and gas emissions are analyzed to enhance the understanding of safety management. In addition, the current state and enhancement opportunities for the second life of electric vehicle batteries are presented. The research highlights the integral role of retired power batteries in applications such as energy storage, communication bases, and streetlights. It is indicated that ensuring safety through robust early warning systems is of paramount importance. Ultimately, this paper envisions a sustainable future, driven by innovative strategies that facilitate the effective utilization of retired batteries in the new energy automobile industry.
Construction of Oligorotaxanes with Hydrogen‐Bonded Aramide Macrocycles through Threaded Host‐Guest Complexation
Authors: Huang Song , Li Xiaowei , Cai Yimin , Feng Wen , Yuan Lihua 
Published: December 2023

AbstractThe development of efficient and selective organic synthetic approaches for complex molecules has garnered significant attention due to the need for precise control over molecular structures and functions. Rotaxanes, a type of mechanically interlocked molecules (MIMs), have shown promising applications in various fields including sensing, catalysis, and material science. However, the highly selective synthesis of oligo[n]rotaxanes (mostly n≥3) through controlling host‐guest complexation and supramolecular threading assembly process still remains an ongoing challenge. In particular, the utilization of two‐dimensional (2D) macrocycles with structural shape‐persistency for the synthesis of oligo[n]rotaxanes is rare. In this concept, research on cooperatively threaded host‐guest complexation with hydrogen‐bonded (H‐bonded) aramide macrocycles and selective synthetic protocols of oligo[n]rotaxanes has been summarized. The high efficiency and selectivity in synthesis are ascribed to the synergistic interplay of multiple non‐covalent bonding interactions such as hydrogen bonding and intermolecular π–π stacking of macrocycles within the unique supramolecular structure of threaded host‐guest complexes. This review focuses on the latest progress in the concepts, synthesis, and properties of H‐bonded aramide macrocycle‐based oligorotaxanes, and presents an in‐depth outlook on challenges in this emerging field.
Carbon Dots based Tissue Equivalent Dosimeter as an Ionizing Radiation Sensor
Authors: dos Santos de Almeida Wandson , Gomes Abegão Luis Miguel , Vinicius Silva Alves Anderson , de Oliveira Souza Silva Jonatas , Oliveira de Souza Susana , d'Errico Francesco , Midori Sussuchi Eliana 
Published: December 2023

AbstractThis work explores the potential of carbon dots as a fluorescent probe in the determination of heavy ions and as an electrochemical biosensor. It also discusses how carbon dots can be introduced into the Fricke solution to potentially serve as an ionizing radiation sensor. The study presents a novel tissue equivalent dosimeter carbon dots‐based as an ionizing radiation sensor. The methodology for the synthesis of Nitrogen‐doped Carbon Dots N‐CDs and the characterization of the material are described. The results show that the N‐CDs have a high sensitivity to ionizing radiation and can be used as a dosimeter for radiation detection. The study also discusses the limitations and challenges of using carbon dots as a dosimeter for ionizing radiation. Overall, this study provides valuable insights into the potential applications of carbon dots in different fields and highlights the importance of further research in this area.
Reactivity of Frustrated Lewis Pair: Carbocation versus Radical Intermediates
Authors: Qu Zheng‐Wang , Zhu Hui , Grimme Stefan 
Published: December 2023

AbstractRecent reports of radical formation within frustrated Lewis pairs (FLPs) suggested that single‐electron transfer (SET) could play an important role in their chemistry especially for C−C coupling. In sharp contrast, our extensive dispersion‐corrected DFT calculations show that although reactive benzhydryl radical along with phosphine radical cation species can be kinetically generated from bulky phosphines and benzhydryl cation, direct P−C hetero‐coupling may lead to bulky phosphonium cation as reactive carbocation transfer reagents to styrene substrates, which is kinetically much more favorable than the recently proposed radical C−C coupling between benzhydryl radical and styrene. Similarly, meta‐stable radical cation Mes3P+⋅ salt is also kinetically accessible via SET reactions of Mes3P and B(C6F5)3 with 0.5 equivalent of p‐O2C6Cl4.
Thioarylation of 6‐Amino‐2,3,6‐trideoxy‐d‐manno‐oct‐2‐ulosonic Acid (IminoKdo): Access to 3,6‐Disubstituted Picolinates and Mechanistic Insights
Authors: Manmode Sujit , Hussain Nazar , Marin Oscar Javier Gamboa , Kato Atsushi , Veytia‐Bucheli José Ignacio , Vincent Stéphane P. , Gauthier Charles 
Published: December 2023

AbstractIn this work, we present a metal‐free coupling protocol for the regio‐ and stereoselective C3‐thioarylation of 6‐amino‐2,3,6‐trideoxy‐d‐manno‐oct‐2‐ulosonic acid (iminoKdo). The developed procedure enables the coupling of electron‐rich, electron‐deficient, and hindered arylthiols, providing a series of C3‐modified iminoKdo derivatives in moderate to good yields. Elucidation of active species through controlled experimental studies and time‐lapse 31P NMR analysis provides insights into the reaction mechanism. We demonstrate that, following a tandem Staudinger/aza‐Wittig reaction of an azido‐containing keto ester, an inseparable equimolar mixture of imine/enamine is formed. The enamine then undergoes a Stork‐like nucleophilic attack with the in situ‐formed disulfide reagent, resulting in the formation of the coupling products. Additionally, we describe a rarely reported acid‐promoted aromatization of the C3‐thioarylated iminoKdo skeleton into 3,6‐disubstituted picolinates, which are reminiscent of dichotomines.
Stabilization and One Electron Reduction of a Silicon Analogue of a Carboxylic Acid Anhydride
Authors: Jiang Yixiao , Yuvaraj K. , Rajeshkumar Thayalan , Feng Lim Li , Cox Nicholas , Maron Laurent , Jones Cameron 
Published: December 2023

AbstractReaction of the 1,2‐disilylenes {(DipArAm)Si}2 (DipArAm=[(NDip)2CAr]−, Dip=2,6‐diisopropylphenyl, Ar=4‐C6H4But (Ar’) 1 a or Ph 1 b) and two abnormal N‐heterocyclic silylenes, (DipArAm)SiOCSi{(NDip)2CAr} (Ar=Ar’ 3 a or Ph 3 b) with N2O led to formation of unprecedented examples of uncoordinated silicon analogues of carboxylic acid anhydrides, (DipArAm)(O=)SiOSi(=O)(DipArAm) (Ar=Ar’ 2 a or Ph 2 b). Both compounds have been fully characterized, and the mechanism of formation of one explored using DFT calculations. Reduction of sila‐acid anhydride 2 a with a dimagnesium(I) compound, [{(MesNacnac)Mg}2] (MesNacnac=[(MesNCMe)2CH]−, Mes=mesityl), led to the one‐electron reduction of the anhydride and formation of a magnesium complex of a sila‐acid anhydride radical anion [(MesNacnac)Mg{(OSi(DipAr’Am)}2O] 5. A combination of EPR spectroscopic studies and DFT calculations reveal the unpaired electron to largely reside on one of the amidinate ligands of the complex.
Photoredox‐Catalyzed Preparation of Sulfones Using Bis‐Piperidine Sulfur Dioxide – An Underutilized Reagent for SO2 Transfer
Authors: Griffiths Oliver M. , Esteves Henrique A. , Emmet Darcy C. , Ley Steven V. 
Published: December 2023

AbstractSulfonyl groups are widely observed in biologically relevant molecules and consequently, SO2 capture is an increasingly attractive method to prepare these sulfonyl‐containing compounds given the range of SO2‐surrogates now available as alternatives to using the neat gas. This, along with the advent of photoredox catalysis, has enabled mild radical capture of SO2 to emerge as an effective route to sulfonyl compounds. Here we report a photoredox‐catalyzed cross‐electrophile sulfonylation of aryl and alkyl bromides making use of a previously under‐used amine‐SO2 surrogate; bis(piperidine) sulfur dioxide (PIPSO). A broad selection of alkyl and aryl bromides were photocatalytically converted to their corresponding sulfinates and then trapped with various electrophiles in a one‐pot multistep procedure to prepare sulfones and sulfonamides.
Dynamic tuft cell expansion during gastric metaplasia and dysplasia
Authors: Jang Bogun , Kim Hyesung , Lee Su‐Hyung , Won Yoonkyung , Kaji Izumi , Coffey Robert J , Choi Eunyoung , Goldenring James R 
Published: December 2023

AbstractTuft cells are chemosensory cells associated with luminal homeostasis, immune response, and tumorigenesis in the gastrointestinal tract. We aimed to elucidate alterations in tuft cell populations during gastric atrophy and tumorigenesis in humans with correlative comparison to relevant mouse models. Tuft cell distribution was determined in human stomachs from organ donors and in gastric pathologies including Ménétrier's disease, Helicobacter pylori gastritis, intestinal metaplasia (IM), and gastric tumors. Tuft cell populations were examined in Lrig1‐KrasG12D, Mist1‐KrasG12D, and MT‐TGFα mice. Tuft cells were evenly distributed throughout the entire normal human stomach, primarily concentrated in the isthmal region in the fundus. Ménétrier's disease stomach showed increased tuft cells. Similarly, Lrig1‐Kras mice and mice overexpressing TGFα showed marked foveolar hyperplasia and expanded tuft cell populations. Human stomach with IM or dysplasia also showed increased tuft cell numbers. Similarly, Mist1‐Kras mice had increased numbers of tuft cells during metaplasia and dysplasia development. In human gastric cancers, tuft cells were rarely observed, but showed positive associations with well‐differentiated lesions. In mouse gastric cancer xenografts, tuft cells were restricted to dysplastic well‐differentiated mucinous cysts and were lost in less differentiated cancers. Taken together, tuft cell populations increased in atrophic human gastric pathologies, metaplasia, and dysplasia, but were decreased in gastric cancers. Similar findings were observed in mouse models, suggesting that, while tuft cells are associated with precancerous pathologies, their loss is most associated with the progression to invasive cancer.
Oral anticoagulant prescribing among patients with cancer and atrial fibrillation in England, 2009–2019
Authors: Ajabnoor Alyaa M. , Parisi Rosa , Zghebi Salwa S. , Ashcroft Darren M. , Faivre‐Finn Corinne , Morris Charlotte , Mamas Mamas A. , Kontopantelis Evangelos 
Published: December 2023

AbstractBackgroundAnticoagulation of patients with atrial fibrillation (AF) and cancer is challenging because of their high risk for stroke and bleeding. Little is known of the variations of oral anticoagulant (OAC) prescribing in patients with AF with and without cancer.MethodsPatients with first‐time AF during 2009–2019 from the Clinical Practice Research Datalink were included. Cancer diagnosis was defined as a history of breast, prostate, colorectal, lung, or hematological cancer. Competing‐risk analysis was used to assess the risk of OAC prescribing in patients with AF and cancer adjusted for clinical and sociodemographic factors.ResultsOf 177,065 patients with AF, 11.7% had cancer. Compared to patients without cancer, patients with cancer were less likely to receive OAC: prostate cancer (subhazard ratio [SHR], 0.95; 95% CI, 0.91–0.99), breast cancer (SHR, 0.93; 95% CI, 0.89–0.98), colorectal cancer (SHR, 0.93; 95% CI, 0.88–0.99), hematological cancer (SHR, 0.70; 95% CI, 0.65–0.75), and lung cancer (SHR, 0.44; 95% CI, 0.38–0.50). The cumulative incidence function (CIF) of OAC prescribing was lowest for patients with lung cancer and hematological cancer compared with patients without cancer. The difference between the CIF of OAC prescribing in patients with and without cancer becomes narrower in the most deprived areas. Elderly patients (aged ≥85 years) overall had the lowest CIF of OAC prescribing regardless of cancer status.ConclusionsIn patients with AF, underprescribing of OAC is independently associated with certain cancer types. Patients with hematological and lung cancer are the least likely to receive anticoagulation therapy compared with patients without cancer. Underprescribing of OAC in cancer is linked to old age. Further studies of patients with AF and cancer are warranted to assess the net clinical benefit of anticoagulation in certain cancer types.
Can end‐user feedback in social media be trusted for software evolution: Exploring and analyzing fake reviews
Authors: Khan Javed Ali , Ullah Tahir , Khan Arif Ali , Yasin Affan , Akbar Muhammad Azeem , Aurangzeb Khursheed 
Published: December 2023

SummaryEnd‐user feedback in social media platforms, particularly in the app stores, is increasing exponentially with each passing day. Software researchers and vendors started to mine end‐user feedback by proposing text analytics methods and tools to extract useful information for software evolution and maintenance. In addition, research shows that positive feedback and high‐star app ratings attract more users and increase downloads. However, it emerged in the fake review market, where software vendors started incorporating fake reviews against their corresponding applications to improve overall software ratings. For this purpose, we conducted an exploratory study to understand how end‐users register and write fake reviews in the Google Play Store. We curated a research data set containing 68,000 end‐user comments from the Google Play Store and a fake review generator, that is, the Testimonial generator (TG). Its purpose is to understand fake reviews on these platforms and identify the common patterns potential end‐users and professionals use to report fake reviews by critically analyzing the end‐user feedback. We conducted a detailed survey at the University of Science and Technology Bannu, Pakistan, to identify the intelligence and accuracy of crowd‐users in manually identifying fake reviews. In addition, we developed a ground truth to be compared with the results obtained from the automated machine and deep learning (M&DL) classifier experiment. In the survey, 512 end‐users participated and recorded their responses in identifying fake reviews. Finally, various M&DL classifiers are employed to classify and identify end‐user reviews into real and fake to automate the process. Unlike humans, the M&DL classifiers performed well in automatically classifying reviews into real and fake by obtaining much higher accuracy, precision, recall, and f‐measures. The accuracy of manually identifying fake reviews by the crowd‐users is 44.4%. In contrast, the M&DL classifiers obtained an average accuracy of 96%. The experimental results obtained with various M&DL classifiers are encouraging. It is the first step towards identifying fake reviews in the app store by studying its implications in software and requirements engineering.
Understanding the Nature of Vibro‐Polaritonic States in Water and Heavy Water
Authors: Kadyan Akhila , Suresh Monu P. , Johns Ben , George Jino 
Published: December 2023

AbstractVery recent experiments on vibrational strong coupling tend to modify chemical reactivity, energy transfer, and many other physical properties of the coupled system. This is achieved without external stimuli and is very sensitive to the vibrational envelope. Water is an excellent vibrational oscillator, which is being used for similar experiments. However, the inhomogeneously broad OH/OD stretching vibrational band make it complicated to characterize the vibro‐polaritonic states spectroscopically. In this paper, we performed vibrational strong coupling and mapped the evolution of vibro‐polaritonic branches from low to high concentration of H2O and measured the on‐set of strong coupling. The refractive index dispersion is correlated with the cavity tuning experiments. These results are further compared with transfer matrix simulations. Simulated data deviate as noted in the dispersion spectra as the system enters into ultra‐strong coupling due to enhanced self‐dipolar interactions. Hopfield coefficients calculation shows that even at ±400 cm−1 detuning, the vibro‐polaritonic states still possess hybrid characteristics. We systematically varied the concentration of H2O and mapped the weak, intermediate, and strong coupling regimes to understand the role of inhomogeneously broad OH/OD stretching vibrational band. Our finding may help to better understand the role of H2O/D2O strong coupling in the recent polaritonic chemistry experiments.
“Environmental disclosure greenwashing” and corporate value: The premium effect and premium devalue of environmental information
Authors: Zhou Yiqiang , Chen Lianghua , Zhang Yan , Li Wan 
Published: December 2023

AbstractEnvironmental disclosure is a crucial method for companies to demonstrate their environmental efforts. However, in some institutional contexts, companies may be inclined to “greenwash” their environmental disclosures, strategically seeking social rewards. Anchored on impression management theory, this study delves into the relationship between environmental disclosure and corporate value. The research substantiates the premium effect of environmental information while shedding light on the adverse impact of “environmental disclosure greenwashing” (EDG) on corporate value. Moreover, EDG leads to a further devaluation in the premium effect of environmental information. A more profound analysis reveals that the market trust acts as the mediating mechanism in the premium devaluation effect caused by EDG. Notably, when information user capability and media attention are scrutinized as distinct groups, the impact of EDG displays pronounced heterogeneity. These findings provide a theoretical foundation for verifying the authenticity of corporate environmental disclosures. Additionally, they offer valuable policy insights for rectifying EDG practices and enhancing environmental disclosure mechanisms.
Organic Electrode Materials for Dual‐Ion Batteries
Authors: Tong Yuhao , Wei Yuan , Song Ajing , Ma Yuanyuan , Yang Jianping 
Published: December 2023

AbstractOrganic materials are widely used in various energy storage devices due to their renewable, environmental friendliness and adjustable structure. Dual‐ion batteries (DIBs), which use organic materials as the electrodes, are an attractive alternative to conventional lithium‐ion batteries for sustainable energy storage devices owing to the advantages of low cost, environmental friendliness, and high operating voltage. To date, various organic electrode materials have been applied in DIBs. In this review, we present the development of DIBs with a following brief introduction of characteristics and mechanisms of organic materials. The latest progress in the application of organic materials as anode and cathode materials for DIBs is mainly reviewed. Finally, we also discussed the challenges and prospects of organic electrode materials for DIBs.
Transcription factor 12‐mediated self‐feedback regulatory mechanism is required in DUX4 fusion leukaemia
Authors: Li Zhihui , Jiang Minghao , Wang Junfei , Zhuo Zhiyi , Zhang Shiyan , Tan Yangxia , Hu Weiguo , Zhang Hao , Meng Guoyu 
Published: December 2023

AbstractBackgroundIGH::DUX4 is frequently observed in 4% B‐cell acute lymphoblastic leukaemia patients. Regarding the IGH::DUX4‐driven transactivation and alternative splicing, which are the main reasons behind this acute leukaemia outbreak, it remains unclear how transcriptional cofactors contribute to this oncogenic process. Further investigation is required to elucidate their specific role in leukaemogenesis.MethodsIn order to investigate the cofactors of IGH::DUX4, integrated mining of Chromatin immunoprecipitation (ChIP)‐sequencing and RNA‐sequencing of leukaemia cells and patient samples were conducted. Furthermore, to elucidate the synergistic interaction between transcription factor 12 (TCF12) and IGH::DUX4, knockdown and knockout experiment, mammalian two‐hybridisation assay, co‐immunoprecipitation and in situ proximity ligation assays were carried out. Additionally, to further investigate the direct interaction between TCF12 and IGH::DUX4, AI‐based structural simulations were utilised. Finally, to validate the synergistic role of TCF12 in promoting IGH::DUX4 leukaemia, cell proliferation, apoptosis and drug sensitivity experiments were performed.ResultsIn this study, we observed that the IGH::DUX4 target gene TCF12 might be an important cofactor/helper for this oncogenic driver. The co‐expression of IGH::DUX4 and TCF12 resulted in enhanced DUX4‐driven transactivation. Supportively, knockdown and knockout of TCF12 significantly reduced expression of IGH::DUX4‐driven target genes in leukaemia REH (a precursor B‐cell leukaemia cell line) and NALM‐6 cells (a precursor B‐cell leukaemia cell line). Consistently, in TCF12 knockout cells, the expression of structure‐based TCF12 mutant, but not wild‐type TCF12, failed to restore the TCF12–IGH::DUX4 crosstalk and the synergistic transactivation. More importantly, the breakdown in TCF12–IGH::DUX4 cooperation impaired IGH::DUX4‐driven leukaemia cell survival, caused sensitivity to the chemotherapy.ConclusionsAltogether, these results helped to define a previously unrecognised TCF12‐mediated positive self‐feedback regulatory mechanism in IGH::DUX4 leukaemia, which holds the potential to function as a pivotal drug target for the management of this particular form of leukaemia.Highlights
Transcription factor 12 (TCF12) is a new novel cofactor in IGH::DUX4 transcriptional complexes/machinery.
TCF12 mediates a positive self‐feedback regulatory mechanism in IGH::DUX4‐driven oncogenic transaction.
IGH::DUX4–TCF12 structure/cooperation might represent a potent target/direction in future drug design against B‐cell acute lymphoblastic leukaemia.
Voltammetric approach to measuring free acid in anhydride and ester based on benzoquinone electrochemical reduction
Authors: Liu Yuhong , Lin Mi , Wang Jianguo 
Published: December 2023

AbstractFree acids commonly exist in anhydride and esters because they are unstable and tend to break down into free acids, which affect the quality of subsequent products in industrial production. Phthalic anhydride and ethyl acetate undergo hydrolysis reactions to form phthalic acid and acetic acid. A differential pulse voltammetry method for the determination of phthalic acid and acetic acid was developed with a bare glassy carbon electrode. Phthalic acid and acetic acid caused a new cathodic peak at more positive potential during the reduction of 1,4‐benzoquinone in acetonitrile or aqueous solution. The new peaks are attributed to the drastic increase in pH at the electrode surface caused by the consumption of protons in the benzoquinone reduction reaction. The peak current of the new cathodic peak was dependent on the concentration of phthalic acid and acetic acid but independent of BQ, phthalic anhydride, and ethyl acetate. This method does not cause hydrolysis of anhydride and ester because no external base is introduced. Furthermore, the method is sensitive, rapid, and does not require pretreatment.