bluuebunny/crossref_metadata_2025_split huggingface dataset:
Designing a Registration System for Kidney Transplant Patients with BK Virus Infection in the Transplant Centers of Isfahan Province: Objectives, Design, and Introducing Under Study Indices
Authors: Mortazavi Mojgan , Moinzadeh Firouzeh , Shahidi Shahrzad , Seyrafian Shiva , Taheri Shahram , Khajeh Azad Mehdi 
Published: January 2025

Abstract

Background:
Notice to the importance of BK virus infection in kidney transplant patients, the present study aimed to present a protocol related to design aspects and implement a registration system for kidney transplant patients with BK virus infection in Isfahan Province, Iran.

Method:
The design process and different aspects of implementation and preparation of the platform for the registration of kidney transplant patients with BK virus infection were presented in this study. Indices related to the diagnosis, monitoring of the course of the disease, and the most important criteria related to the disease caused by BK virus and treatment of BK virus infection in kidney transplant patients were searched in reliable scientific databases such as PubMed, Scopus, Up-To-Date, ScienceDirect, and Web of Science. A team consisting of experts in nephrology, biostatistics, and epidemiology evaluated the specified variables as an expert panel and evaluated the content validity of the checklists designed quantitatively and qualitatively to finalize them.

Results:
The checklist was finalized in three sections: 1) demographic variables (age, gender, education,…), 2) clinical variables (primary cause of kidney failure, disease history, history of kidney disease in the family, laboratory and diagnostic parameters, clinical manifestations…), and 3) microbiologic information of BK virus infection. This information can be used for the diagnosis, treatment, and follow-up of the patient.

Conclusions:
Our registry for kidney transplant patients with BK virus infection among the few ones in the world can provide a comprehensive valuable information collection about the risk factors and the course of changes in various indices in these patients and may improve the treatment process.
Client Waiting Time and Satisfaction in a Diagnostic Center Operating Under a Public–private Partnership at a Tertiary Healthcare Facility in Lagos, Nigeria
Authors: Adeniran Adeyinka , Adegboyega Olukayode , Bashir Khadija , Kumuyi Babatunde Rufus 
Published: January 2025

Abstract

Introduction:
This study is of profound significance as it presents a unique and novel assessment of client waiting time in a private–public partnership diagnostic center at a tertiary healthcare center in Lagos. It provides invaluable insights into the healthcare service delivery in Nigeria, a topic of increasing importance in the healthcare sector.

Materials and Methods:
This study employed a rigorous and comprehensive descriptive and cross-sectional approach conducted between February 2023 and June 2023 in Lasuth. The aim was to assess the client waiting time and patients’ satisfaction with services received, and a systematic sampling technique was used to select 1700 patients in the BT diagnostic center. These patients were then interviewed using interviewer-administered questionnaires, ensuring a comprehensive understanding of their experiences. The Chi-square and Fisher’s exact tests were used to test the hypothesis.

Results:
The mean age of the participants was 38.53 (standard deviation ± 4.78). Most patients were married (46.2%) and most respondents were unskilled (34.1%). The mean waiting time to register was 24.45 ± 54.32, ranging from a minimum of 1 min to a maximum of 1435 min. More than half (62.8%) of the patients were satisfied with the waiting time to complete their test. The mean duration of investigation in minutes is 32.29 ± 38.13, ranging from a minimum of 0 min to 300 min. The mean waiting time in the laboratory was 31.09 ± 39.84, ranging from 1 min to 240 min, while the mean waiting time to obtain the results from the laboratory was 1835.86 ± 4093.34, with a median time of 120 min. More than half (61.3%) of the patients were satisfied, with a mean of 75.55 ± 13.58, while 22.6% were very satisfied. There was a significant association between sociodemographic variables, waiting time and patient satisfaction, indicating that sociodemographic variables affect patient satisfaction with waiting time or services rendered in the diagnostic center.

Conclusion/Recommendation:
Patients with shorter waiting times were more satisfied than those with longer waiting times. This underscores the urgent need to address the waiting times in healthcare service delivery. By doing so, we can significantly improve patient satisfaction and the quality of care received, inspiring positive change in the healthcare system.
Unpopular yet Invaluable: The Role of Transrectal Ultrasonography in Evaluating Gynecological Pathologies
Authors: Aderibigbe Adeniyi Sunday , Adesunkanmi Omololu O. , Aderibigbe Adeshewa , Ijarotimi Omotade A. , Odewumi Kayode A. 
Published: January 2025

Abstract

Background:
The popular and sensitive transvaginal sonography (TVS) is not always applicable for evaluating pelvic organs in some women such as those with intact hymen (IH) or with endovaginal lesions. This study reviewed gynecologic conditions where transrectal sonography (TRS) was used as an alternative for TVS.

Materials and Methods:
This retrospective study reviewed TRS reports and images of women who had complementary TRS following equivocal initial transabdominal gynecological scan. All scans were carried out in a tertiary radiodiagnostic clinic in South West Nigeria over an 18-month period (April 2023 to October 2024). Relevant published English literatures comparing the sensitivity/image quality of TRS and TVS were also presented.

Results:
Among the 16 cases retrieved, 10 (62.5%) had IH, whereas 6 (37.5%) had no IH (NIH); the median age (interquartile range) for the two groups were 20 (18–28) years and 64 (44–69) years, respectively. Major indications for TRS among the IH were abnormal uterine bleeding (40.0%), primary amenorrhea (30.0%), and menorrhagia/severe dysmenorrhea (20.0%), whereas pelvic organ prolapse (66.7%) and TRS-guided intrauterine device (IUD) removal (33.3%) were the indications among the NIH. The most common TRS findings among the IH group included polycystic ovarian morphology (50.0%), absent or hypoplastic uterus/streak ovaries (30.0%), and submucous uterine fibroid nodules (30.0%), while the 50% of the NIH women had cystoceles and 33.3% had successful IUD removal under TRS-guidance.

Conclusion:
When it is not possible to use TVS in women with gynecological complaints, TRS is a suitable and inexpensive alternative method for evaluating the endometrium and adnexal structures.
Ne bis in idem, acumulación de sanciones penales y administrativas por un mismo hecho y nuevo artículo 78 bis del Código Penal
Authors: Escobar Veas Javier 
Published: January 2025

Los casos de acumulación de sanciones penales y administrativas por un mismo hecho, cuya legitimidad ha sido cuestionada por la jurisprudencia principalmente desde la perspectiva de la prohibición de bis in idem, han aumentado significativamente en las últimas décadas. En agosto de 2023, la Ley 21.595 incorporó un nuevo artículo 78 bis al Código Penal, norma cuyo objeto es regular la acumulación o compatibilidad de sanciones penales y administrativas respecto de un mismo hecho. Este trabajo tiene por objeto analizar la aplicación de la prohibición de sanción múltiple en Chile, con especial referencia al nuevo artículo mencionado.
Exploration of phthalazine bearing oxadiazolyl–triazole hybrids as selective breast cancer agents: computational docking interactions
Authors: Kumar Konda Santosh , Kuna Sateesh , Pandiri Sreedhar , Akarapu Premalatha , Bhoomandla Srinu , Veera Venkata Nanda Kishore Pilli 
Published: January 2025

In this study, a series of novel phthalazine derivatives bearing 1,3,4–oxadiazolyl–1,2,3–triazole moiety were designed, synthesized, and evaluated for anticancer activity. The formation targeted compounds were conﬁrmed for their structure by means of various spectral–analytical techniques like 1H-NMR, 13C-NMR, FT-IR, elemental analysis, and mass spectrum. All synthesized compounds were screened for anticancer activity against three different human breast cancer cell lines MCF-7, T-47D, and MDA-MB-231. From screening results, compound 5f exhibited the most potent anticancer activity (IC50 = 10.21 ± 2.2, 7.53 ± 0.1 µM) towards T-47D, MCF-7 cell lines and 4b, 5b demonstrated the highest % growth of inhibition (61.25 ± 0.52, 62.48 ± 0.20 µg/mL) against T-47D, and MCF-7 cell lines, respectively, which is equivalent to that reported by the standard cisplatin. The docking study strongly favours compound 4d, 5a, 5e, and 5f to be a dehydrogenase type 1 complexed in breast cancer inhibitor as it displayed a similar interaction to cisplatin (3HB4). Ligand 5f exhibited amino acid interactions and having docking score –11.53 kcal/mol, respectively. The in-silico pharmacokinetics studies support the results obtained from docking and biological evaluation and displayed favourable pharmacokinetic profile for a drug to be orally available.
Bull. Chem. Soc. Ethiop. 2025, 39(4), 731-748.
DOI: https://dx.doi.org/10.4314/bcse.v39i4.10
Magnetic properties and exchange bias behavior of poly(4-(octyloxy) phenyl-5- (thiophen-3-yl)-2-naphthoate): Insights from temperature-dependent magnetization and EPR spectroscopy
Authors: Esakki Muthu Sankaran , Gaddala Baburao , Ananthakrishnan  , Somanathan  , Mandal  , Kannan Karthik , Kumar Balaraman Nirmal , Arumugam Sonachalam 
Published: January 2025

The polymer POPTN was investigated to elucidate its magnetic and optoelectronic properties, with particular emphasis on charge carrier mobility, dichroic behaviour, and magnetic interactions. Electron paramagnetic resonance (EPR) studies confirmed delocalization over the naphthalene side chains, contributing to the observed paramagnetic behaviour at room temperature. Temperature-dependent magnetic studies revealed paramagnetic behaviour at higher temperatures transitioning to weak ferromagnetism below 10 K. Curie-Weiss analysis indicated antiferromagnetic (AFM) coupling with a paramagnetic Curie temperature (θP) of -203 K. Exchange bias (EB) measurements demonstrated a significant hysteresis loop shift at 2 K, diminishing with increasing temperature and vanishing near 20 K. The maximum exchange bias field (HE) was observed to be 133 Oe at 2 K, attributed to the coexistence of ferromagnetic (FM) and AFM interactions. The interplay of AFM and FM coupling, along with π-π stacking facilitated by the naphthyl moiety, influenced the magnetic properties and anisotropy.
Bull. Chem. Soc. Ethiop. 2025, 39(4), 791-798.
DOI: https://dx.doi.org/10.4314/bcse.v39i4.14
Synthesis of indole borate ligand with Ni(II) and Cu(II) complexes
Authors: Mohammed Noori Khaleel Asmaa 
Published: January 2025

A new borate derivative (2,2',2'',2'''-((ʎ4-boranetetrayl)tetrakis(1H-indole-1,3-diyl))tetraacetic acid)(BIN) was synthesized from the reaction of indole-3-acetic acid (IAA) with sodium tetrahydroborate NaBH4 at a 4:1 mole ratio. This ligand was characterized by 1HNMR, FTIR, electronic spectra (UV-Vis.) thermal analysis (TG and DTG), elemental analysis (CHN) and melting point. Nickel and copper complexes were also synthesized and characterized by CHN, UV-Vis, atomic absorption, FTIR, melting point, magnetic susceptibility and molar conductivity. Results of analyses were in agreement with suggested structures. The results showed that the structure of nickel complex was octahedral while the copper complex was square planar and both complexes were nonelectrolytes. Antimicrobial activity against four kinds of bacteria Staphylococcus aureus and Streptococcus (G+), E. coli and Pseudomonas aeruginosa (G‒) as well as one fungus Candida albican exhibited that the copper complex has higher antimicrobial activity. Total antioxidant results showed that the BIN ligand has higher activity at 50 and 100 μg/mL while the copper complex has more antioxidant activity at 150 μg/mL.
Bull. Chem. Soc. Ethiop. 2025, 39(4), 703-712.
DOI: https://dx.doi.org/10.4314/bcse.v39i4.8
A Atuação do Tecnólogo em Radiologia na Medicina Veterinária- Um trabalho de campo.
Authors: De Souza Jonhny , Campos Fábio , De Souza Francisca , Valdevino Thácia , Rocha Ediane 
Published: January 2025

A didática representa uma das conjunturas fundamentais do campo de atuação tecnológica da radiologia na história, sendo um ramo central das concepções a radiologia veterinária vem expandindo e trazendo métodos de diagnósticos cada vez mais sofisticados e com isso proporcionando rapidez na resolução dos casos clínicos na clínica de pequenos e grandes animais. Ao contrário da medicina humana, na medicina veterinária o técnico e tecnólogo trabalham com várias espécies de animais totalmente diferentes daquela no qual está acostumado, a espécie humana. Mediante o fato supracitado, a necessidade de possuir profissionais devidamente capacitados no ambiente de imaginologia da medicina veterinário é de natureza carente e quase inexistente. Pensando nisso, o presente trabalho discute sobre a importância da participação do profissional radiologista frente ao setor de imagem, abordando parâmetros de exposição e fundamentos físicos do equipamento. Para tanto, seguindo os moldes do trabalho de campo enquanto base norteadora da referida pesquisa, foi-se utilizado dados do Hospital Veterinário do Centro Universitário de Patos – UNIFIP, durante 6 meses do período letivo do semestre de 2023.2 conseguinte ao estágio supervisionado de radiologia médica veterinária, nela foi abordado protocolos de exposição em equipamento de raio- x como cálculos de espessura da área irradiada, Kv e mAs em cães e gatos, levando em consideração que o presente equipamento era comumente utilizado na área médica humanista.
PENGARUH TOTAL ASSET TURNOVER (TATO), RETURN ON ASSET (ROA) DAN DEBT TO ASSET RATIO (DAR) TERHADAP PERTUMBUHAN LABA PADA PT. ADHI KARYA (PERSERO) TBK
Authors: Andriansyah Muhamad Rizki , Pratiwi Aliah 
Published: January 2025

Abstrak – Penelitian ini bertujuan untuk mengetahu pengaruh Total Asset Turnover, Return On Asset dan Debt to Asset Ratio terhadap pertumbuhan laba Pada PT. Adhi Karya Persero Tbk. Instrumen penelitian ini yaitu menggunakan laporan keuangan di antara laporan neraca dan laba rugi pada PT. Adhi Karya Persero Tbk. Adapun data yang digunakan dalam instrumen penelitian ini yaitu data laba bersih, total penjualan, total hutang dan total aset dari tahun 2013-2022. Sedangkan teknik pengambilan sampel yang digunakan adalah purposive sampling. Kriterianya didasarkan pada ketersediaan data terupdate. Data dalam penelitian ini diolah menggunakan SPSS. Metode pengujian hipotesis menggunakan taraf signifikan 5%. Hasil penelitian menunjukan bahwa Total Asset Turnover (TATO) tidak berpengaruh signifikan terhadap pertumbuhan laba, Return On Asset (ROA) tidak berpengaruh signifikan terhadap pertumbuhan laba dan Debt to Asset Ratio (DAR) tidak berpengaruh signifikan terhadap pertumbuhan laba. Serta secara simultan Total Asset Turnover (TATO), Return On Asset (ROA) dan Debt to Asset Ratio (DAR) tidak berpengaruh terhadap pertumbuhan laba pada PT. Adhi karya Tbk
PENGARUH CONTENT MARKETING DAN CUSTOMER REVIEW TERHADAP KEPUTUSAN PEMBELIAN KONSUMEN DI MARKETPLACE TIKTOK SHOP (STUDI KASUS PADA MASYARAKAT KOTA BIMA)
Authors: Azhari A.Rahman , Ismunandar Ismunandar 
Published: January 2025

Abstrak – Penelitian ini bertujuan untuk mengetahui pengaruh Content Marketing dan Customer Review terhadap Keputusan Pembelian konsumen di Marketplace TikTok Shop (Studi kasus pada Masyarakat Kota Bima). Metode penelitian yang digunakan dalam penelitian ini adalah metode survei dengan bentuk pernyataan tertulis melalui kuesioner sebanyak 96 responden sebagai sampel dalam penelitian ini. Analisis data menggunakan uji validitas, uji reabilitas, uji asumsi klasik (uji normalitias, uji multikolenearitas, uji heteroskedastisitas dan uji autokorelasi), analisis regresi berganda, koefisien korelasi, koefisien determinasi dan uji hipotesis (uji t dan uji F) melalui aplikasi perangkat lunak Statistical Product and Service Solution Ver.24 (SPSS). Hasil penelitian menunjukkan bahwa Content Marketing berpengaruh signifikan terhadap Keputusan Pembelian, Customer Review berpengaruh signifikan terhadap Keputusan Pembelian serta Content Marketing dan Customer Review berpengaruh signifikan terhadap Keputusan Pembelian. Kata kunci: Content Marketing, Customer Review, Keputusan Pembelian.
Mathematical Modeling and analysis of dynamics of Neisseria Gonorrhea Disease with Self Protection, Treatment and Natural Immunity
Authors: Ullah Irfan , Ahmad Imtiaz , Ali Nigar , Ahmad Zubair , . El Agamy Rasha F 
Published: January 2025

We present a mathematical framework for the infection of Neisseria gonorrhea in this article. Compared to a number of earlier models in the literature, the new model is more comprehensive and covers a wide range of concepts. The local and global stability, sensitivity analysis, of the model are examined. The results are illustrated with algorithmic experiments. A computational analysis of the model is examined. highlighting the impact of different values of parameters on the model’s dynamics and offering potential avenues for further research. In this article, we present a robust mathematical framework for modeling the infection dynamics of Neisseria Gonorrhoea. Unlike earlier models in the literature, our approach is more comprehensive, integrating a wide array of concepts related to the infection process. We conduct an in-depth analysis of both local and global stability, along with a sensitivity analysis of the model parameters. The results are supported by algorithmic experiments that illustrate the model’s behavior under varying conditions. Additionally, we perform a thorough computational analysis, emphasizing how different parameter values influence the model’s dynamics. This work not only enhances our understanding of gonorrhea transmission but also identifies potential avenues for further research in this critical area of public health. Keywords: Neisseria Gonorrhea, Stability analysis, Numerical simulation, Sensitivity analysis
Control of Marburg Virus Disease Spread in Humans under Hypersensitive Response through Fractal-Fractional
Authors: Faiz Khurram , Ahmad Aqeel , Khan Muhammad Suleman , Abbas Safdar 
Published: January 2025

The primary objective of this research is to examine the model of Marburg virus disease with therapy to prevent the infections from spreading throughout the community due to saliva, urine, and feces. A mathematical model is established using the created hypothesis for a healthy environment in order to examine the different rates of Marburg virus disease after taking control measures with treatment for different protection. The model is then converted into a fractional ordered model for continuous monitoring, including theoretical solutions, by using the Fractal Fractional operator. The model’s global stability is studied through Lyapunov derivative by equilibrium and endemic point of model. Both qualitative and quantitative analysis is done on a proposed model with the power law kernel, with particular focus on unique solutions, positivity, and boundedness. By using of fixed point theory and the Lipschitz condition, there is only one exact solution. By confirming the Lyapunov function globally, equilibrium points that are both endemic and disease-free are checked for stability. Numerical simulations are utilized to investigate the effects of the fractal fractional operator on the generalized form of the power law kernel using a two-step Lagrange polynomial approach for ongoing monitoring of the Marburg virus disease and treatment strategies. The simulations show how different parameters affect the illness. In order to simulate the actual behavior and management of Marburg virus disease produced by saliva, urine, and feces and to implement control measures for a healthy environment with a hypersensitive reaction (HR), simulations have been constructed. This type of research will be helpful in figuring out how diseases spread and in developing management strategies based on our verified results for human in community.
DETERMINAN YANG MEMPENGARUHI IMUNISASI PENTAVALEN LANJUTAN
Authors: Meliyanti Fera , Heryanto Eko 
Published: January 2025

Dalam mempertahankan tingkat kekebalan yang optimal diperlukan imunisasi lanjutan. Imunisasi lanjutan merupakan ulangan dari imunisasi dasar untuk memperpanjang masa perlindungan anak yang telah mendapatkan imunisasi dasar. Penggunaan imunisasi pentavalen (DPT-HB-HIB) untuk imunisasi bayi dan balita telah diluncurkan pada tahun 2014 oleh Kemenkes RI . Anak-anak Indonesia akan lebih terlindungi dari ancaman penyakit-penyakit yang dapat dicegah dengan imunisasi (PD3I), dengan ditambahkannya vaksin Haemophilus influenzae type b (Hib) yang diberikan bersamaan dengan vaksin DPT dan Hepatitis B. Vaksin pengembangan vaksin tetravalen (DPT-HB) kombinasi buatan indonesia ini disebut Pentavalen, karena merupakan gabungan dari 5 antigen, yaitu DPT (Difteri, Pertusis dan Tetanus), Hepatitis B, serta HiB. Penelitian ini bertujuan untuk mengetahui determinan yang mempengaruhi kelengkapan imunisasi pentavalen lanjutan. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan pendekatan cross sectional. Populasi dalam penelitian ini adalah anak umur 18-24 bulan di wilayah kerja UPTD Puskesmas Tanjung Baru dari bulan Januari sampai dengan bulan Maret 2022 berjumlah 405 dengan sampel 80 anak berumur 18-24 bulan. Hasil penelitian menunjukkan bahwa ada hubungan yang bermakna antara pendidikan ibu dengan kelengkapan imunisasi pentavalen lanjutan dengan p-value 0,004, ada hubungan yang bermakna antara pengetahuan ibu dengan kelengkapan imunisasi pentavalen lanjutan dengan p-value 0,021, ada hubungan yang bermakna antara sikap ibu dengan kelengkapan imunisasi pentavalen lanjutan dengan p-value 0,009 dan ada hubungan yang bermakna hal ini antara dukungan keluarga dengan kelengkapan imunisasi pentavalen lanjutan dengan p-value 0,012. Dari hasil penelitian tersebut maka diharapkan petugas kesehatan khususnya pemegang program kesehatan ibu dan anak (KIA) dapat memberikan perhatian khusus terhadap ibu-ibu dalam memberikan penyuluhan tentang imunisasi pentavalen lanjutan.