bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kesadaran Hukum Masyarakat dalam Pendaftaran Peralihan Hak Atas Tanah
Authors: Taolin Fitriana Trinengsi , Mujiburohman Dian Aries , Widarbo Koes 
Published: January 2024

Transfers of land rights must be registered at the local land office. However, there are still people who have not registered the transfer of land rights due to low legal awareness. This lack of awareness can have legal repercussions and hinder the objectives of land registration. This research aims to analyze the level of legal awareness of the community regarding the importance of registering the transfer of land rights and the potential impacts that could occur if the community does not carry out this registration in the Banyuraden District. The method used is an empirical legal method with a qualitative approach. Data collection techniques involve observation, interviews, and document study. The results of the analysis show that of the 37 respondents, only 14% have taken concrete action by registering the transfer of their land rights. Thus, it can be concluded that public legal awareness in Banyuraden District is still low. The causes of low legal awareness regarding registration and transfer of land rights involve a number of factors, including lack of socialization, low level of education, lack of interest, limited information, and distrust of the relevant agencies. Meanwhile, potential impacts that may arise as a result of not registering the transfer of rights include legal uncertainty for new rights holders, limitations in carrying out other legal actions, land administration irregularities, and potential land disputes.

Peralihan hak atas tanah wajib didaftarkan di Kantor Pertanahan setempat. Namun, masih ada masyarakat yang belum mendaftarkan peralihan hak tanah karena rendahnya kesadaran hukum. Kurangnya kesadaran ini dapat menimbulkan dampak hukum dan menghambat tujuan pendaftaran tanah. Penelitian ini bertujuan untuk menganalisis tingkat kesadaran hukum masyarakat terhadap pentingnya pendaftaran peralihan hak atas tanah dan potensi dampak yang dapat terjadi jika masyarakat tidak melakukan pendaftaran tersebut di Kalurahan Banyuraden. Metode yang digunakan adalah metode hukum empiris dengan pendekatan kualitatif. Teknik pengumpulan data melibatkan observasi, wawancara, dan studi dokumen. Hasil analisis menunjukkan bahwa dari 37 responden, hanya 14% yang telah mengambil tindakan konkret dengan mendaftarkan peralihan hak atas tanah mereka. Dengan demikian, dapat disimpulkan bahwa kesadaran hukum masyarakat di Kalurahan Banyuraden masih rendah. Penyebab rendahnya kesadaran hukum terkait pendaftaran peralihan hak atas tanah melibatkan sejumlah faktor, antara lain kurangnya sosialisasi, rendahnya tingkat pendidikan, kurangnya minat, keterbatasan informasi, dan ketidakpercayaan terhadap instansi yang terkait. Sementara itu, potensi dampak yang mungkin timbul akibat tidak mendaftarkan peralihan hak meliputi ketidakpastian hukum bagi pemegang hak baru, keterbatasan dalam melakukan perbuatan hukum lainnya, ketidakteraturan administrasi pertanahan, dan potensi sengketa tanah.
Ameliorative Effect of Galium Verum (Rubiaceae Family) Methanolic Extract on Folic Acid-induced Acute kidney Injury in Male Rats.
Authors: Rashed Aya , Mohamed Ayman Saber , Soliman Amel 
Published: January 2024

Background: Antioxidant, sedative, anticancer, and antibacterial properties are among the numerous pharmacological characteristics of Galium verum. Aim: The primary goal of this research was to investigate the therapeutic effects of G. verum extract against folic acid-induced acute kidney injury (AKI). Materials and methods: 18 male rats were assigned into three groups: Control, AKI, and G. verum. AKI was induced by a dose of folic acid (250 mg/kg, i.p.) while G. verum (250 mg/kg) was administrated for 7 consecutive days. Results: G. verum methanol extract contains flavonoids, anthraquinones, tannins, iridoids, triterpenes, steroids, phenols, and saponins, while it free of cardiac glycosides and alkaloids. G. verum extract significantly decreased levels of creatinine, urea, uric acid, sodium, chloride, potassium, microalbumin, malondialdehyde and nitric oxide while it increased creatinine clearance, glutathione reduced, and catalase levels. Meanwhile, histological examination of the kidney’s tissues revealed apparently normal structure. Conclusions: Underlying renal therapeutic mechanisms of G. verum action include a diuretic, antioxidant, and anti-inflammatory properties of G. verum extract resulting in improving kidney structure and enhance recovery of renal function.
The Hepatoprotective Effect of Omega-7 Against Paracetamol-Induced Hepatotoxicity in Male Rats
Authors: Hameed Hadeel Ali , Ali Faris Hassan  
Published: January 2024

Abstract
Paracetamol toxicity, whether accidental or not is a worldwide issue that leads to hepatotoxicity, acute liver failure, as well as irreversible liver injury requiring liver transplantation. Omega-7 is a monounsaturated fatty acid with a number of beneficial properties. The aim of the present study was to assess the potential protective role of omega-7 fatty acid against hepatotoxicity induced by paracetamol in male rats. Thirty male Rats were separated into five groups (six rats in each group) and received the following treatment: group 1 received liquid paraffin orally via gavage tube for seven days successively, group 2 received liquid paraffin orally via gavage tube for seven days successively, and on day eight, rats received a single intraperitoneal injection of paracetamol (500 mg/kg/day), group 3 received omega-7 (300 mg/kg/day) orally via gavage tube for seven days successively, group 4 received omega-7 (100 mg/kg/day) orally via gavage tube for seven days successively, and on day eight, rats received a single intraperitoneal injection of paracetamol (500 mg/kg/day), group 5 received omega-7 (300 mg/kg/day) orally via gavage tube for seven days successively, and on day eight, rats received a single intraperitoneal injection of paracetamol (500 mg/kg/day). On day nine, rats have been sacrificed by cervical dislocation and liver homogenate samples were collected for analysis. This study showed that there was a significant decrease in hepatic superoxide dismutase, catalase, glutathione-peroxidase and glutathione levels, accompanied with significant increase in hepatic malondialdehyde level in paracetamol group compared to the negative control group. However, administration of omega-7 resulted in significant increase in hepatic superoxide dismutase, catalase and glutathione levels and significant decrease in hepatic malondialdehyde level compared to paracetamol group. In conclusion, omega-7 has a protective effect on paracetamol-induced hepatotoxicity in rats.
Keywords: Antioxidant, Hepatotoxicity, Omega-7, Oxidative stress, Paracetamol.
Evolution of transport service architecture in Russia and the Soviet Union (Saratov)
Authors: Nikishin S. A. , Dyadchenko S. F. , Sukhinina E. A. 
Published: January 2024

The article studies in the national history of the architectural typology evolution of transport services in Russia and the Soviet Union. The progress of motor transport since the end of the 19th century and new tasks put forward by this process, require an intensive typological search for innovative architectural solutions. Since the beginning of the 20th century, motor transport services together with the developing motor transport network become significant elements of the urban development, largely determining their new image. The architecture of transport service facilities directly relates to the current development of vehicles in technological and socio-economic aspects.The purpose of the study is to analyze and generalize the architecture typology of the transport service in Russia, depending on technological and social factors.
КОМУНІКАТИВНО-ПРАГМАТИЧНИЙ АСПЕКТ ФУНКЦІОНУВАННЯ СУЧАСНОЇ УКРАЇНСЬКОЇ ВІЙСЬКОВОЇ ЛЕКСИКИ ТА ОСОБЛИВОСТІ ЇЇ ПЕРЕКЛАДУ (НА МАТЕРІАЛІ ГАЗЕТНИХ СТАТЕЙ)
Authors: БЕЖЕНАР Ірина , КУСІК Анастасія 
Published: January 2024

У статті висвітлено результати дослідження комунікативно-прагматичного аспекту вживання сучасної української військової лексики, зокрема емоційно забарвлених військових лексем, та особливостей її перекладу англійською мовою на матеріалі газетних статей на військову тематику, опублікованих у період з 22 лютого 2022 року по листопад 2023 року. Актуальність дослідження обумовлена як стрімким зростанням частотності вживання у медійному просторі військових лексем, у тому числі новоутворених та тих, які змінили своє семантичне наповнення і мають відмінне від загальновизнаного комунікативно-прагматичного навантаження, так і необхідністю формування чіткого, адекватного тлумачення функцій цієї зміненої за своєю семантичною сутністю військової лексики, а також виявлення особливостей її перекладу в сучасних англійсько- та українськомовних ЗМІ. Метою дослідження є виявлення специфіки функціонування української військової лексики в газетних статтях, зокрема її комунікативної прагматики, а також визначення особливостей її відтворення в українсько-англійських та англійсько-українських перекладах. У рамках дослідження розглянуто різноманітні приклади новоутворених військових лексем, вибрані з сучасних публікацій, що присвячені темі війни в Україні; уточнено зміст їх комунікативно-прагматичного навантаження; проаналізовано способи їх відтворення в українсько-англійських та англійсько-українських перекладах. Належну увагу приділено аналізу найчастотніших трансформацій, застосованих для їх перекладу, у тому числі з огляду на урахування комунікативно-прагматичного аспекту їх функціонування.
Aula invertida como un modelo pedagógico en el proceso enseñanza y aprendizaje
Authors: Escobar Salavarría Karen Viviana , Santana Quimis Verónica Jesenia , Velasteguí López Luis Efraín , Hernández Ramón Guzmán 
Published: January 2024

Introducción: El aula invertida es un modelo pedagógico que permite tanto a estudiantes como docentes optimizar el proceso enseñanza, busca intercambiar los roles, el aprendiente enseña los conocimientos previamente aprendidos en la revisión de textos, videos, lecturas y otros contenidos fuera del aula para explicarlo en el entorno áulico. Objetivo: el objetivo general es determinar la importancia del aula invertida doble en el contexto educativo globalizado. Metodología: El diseño fue investigación aplicada, según su enfoque se realizó un estudio cuantitativo, de campo, de carácter transversal y longitudinal. El alcance descriptivo. Los métodos aplicados fueron: deductivo, inductivo, analítico, sintético. La técnica de investigación aplicada fue la encuesta, con el instrumento del cuestionario que permitió investigar las variables del estudio. Resultados: En los resultados se confirma que los estudiantes utilizan aula invertida, lo aprovechan para la realización de actividades prácticas y a la resolución de posibles problemas. Se evidenció la posibilidad de implementar este método para contribuir al aprendizaje activo y fomentar la participación continua en forma colaborativa. Conclusión: Se concluye en el cumplimiento de los objetivos, así como se invierte el orden de la enseñanza en dos momentos, considerando que, el docente enseña en clase, el estudiante aprende y en determinado momento el escolar enseña lo que investigó, profundiza los contenidos y fomenta el aprendizaje colaborativo, lo que permite la aplicación del aula invertida en el contexto áulico. Área de estudio general: Docencia. Área de estudio específica: Emprendimiento y Gestión.
Monitoring Suhu Box Panel dan Voltase Pengisian Baterai pada Base Transceiver Station Berbasis IoT
Authors: Ariyanto Andy , Nurchim Nurchim , Hartanti Dwi 
Published: January 2024

Bermula dari seringnya kehabisan daya baterai cadangan dan tingginya suhu di dalam box panel pada Base Transceiver Station (BTS) Wifi. Permasalahan tersebut dapat diatasi dengan sebuah penelitian sistem monitoring suhu box panel dan voltase pengisian baterai berbasis IoT. Tujuan penelitian ini adalah memantau voltase pengisian baterai dan suhu pada box panel yang diharapkan dapat memberikan informasi bagi user dan teknisi. Hasil penelitian berupa notifikasi telegram yang berisi keadaan voltase pengisian dan suhu box panel. Pengembangan sistem yang digunakan adalah dengan metode prototype. Perancangan dimulai dari menganalisa sistem yang ada, dimana belum ada sistem monitoring voltase pengisian aki dan suhu box panel. Peneliti menggunakan ESP32 sebagai microcontroller, voltage divider dan DHT11. Jika voltase pengisian kurang dari 11 volt dan atau voltase lebih dari 15 volt maka sistem akan mengirimkan pesan Telegram kepada user dan jika suhu lebih dari 35° C maka sistem akan menghidupan relay yang terhubung ke kipas pendingin, dan kipas akan dimatikan ketika suhu turun menyentuh 30° C.
Sex differences in mortality and hospitalization in heart failure with preserved and mid-range ejection fraction: a systematic review and meta-analysis of cohort studies
Authors: Deng You , Zhang Jun , Ling Jitao , Hu Qingwen , Song Tianggang , Xu Yi , Liu Menglu , Wu Yuting , Mei Kaibo , Chen Jiawei , Zhao Huilei , Liu Xiao 
Published: January 2024

IntroductionThe influence of sex on the prognosis of heart failure with preserved or intermediate ejection fraction (HFpEF and HFmrEF) remains uncertain. This study aimed to investigate whether sex differences impact the prognosis of patients diagnosed with HFpEF and HFmrEF.MethodsA comprehensive search across three databases (PubMed, the Cochrane Library, and Embase) was conducted to identify sex-related prognostic cohort studies focusing on HFpEF and HFmrEF. Risk estimates were synthesized using the random effects model. The analysis included 14 cohorts comprising 41,508 HFpEF patients (44.65% males) and 10,692 HFmrEF patients (61.79% males).ResultsAmong HFpEF patients, men exhibited significantly higher rates of all-cause mortality (13 studies; hazard ratio (HR): 1.24, 95% confidence interval (CI): 1.15 to 1.33)) and cardiovascular disease mortality (5 studies; HR: 1.22, 95% CI: 1.14 to 1.31) compared to women. However, no significant difference was observed in HF admissions. For HFmrEF patients, men displayed notably higher all-cause mortality (HR: 1.21, 95% CI: 1.12 to 1.31) but no significant differences in cardiovascular mortality or HF admissions.DiscussionThese findings suggest that male patients diagnosed with HFpEF and HFmrEF may face a more unfavorable prognosis in terms of all-cause mortality. Variations were noted in cardiovascular mortality and HF admissions, indicating potential complexities in sex-related prognostic factors within these heart failure categories. In summary, male patients with HFpEF and HFmrEF may have a more unfavorable prognosis.
Demands, resources and institutional factors in the work of academic staff in Central and Eastern Europe: results of a qualitative research among university teachers in five countries
Authors: Kovács Klára , Dobay Beáta , Halasi Szabolcs , Pinczés Tamás , Tódor Imre 
Published: January 2024

IntroductionThe increased stress, pressure, and organizational change draw attention to the importance of doing research on workplace stress and resources, as well as other sources of stress among university teachers. Based on the job demands-resources theory (JD-R theory) this paper investigates the workplace factors affecting the health and wellbeing of Central and Eastern European (CEE) academics. A further question is, what are the institutional factors that (could) improve or worsen their wellbeing, as well as how they are able to cope with the stress on an individual level.MethodsFor the analyses, seven focus group interviews were conducted with academics from nine higher education institutions in Hungary, Slovakia, Ukraine, Romania, and Serbia (N = 41).ResultsAccording to our results of the focus group interviews the most important workplace difficulties, challenges, and resources are related to teaching roles, interpersonal relationships, support by the management, and infrastructural conditions.DiscussionInstitutions can contribute to the wellbeing and health of the academics primarily by offering free or at least discounted participation in sports, cultural and leisure events, as well as mental health counseling, but it is important for these not to be self-serving (the colleagues from the university should not participate in the programs to make up for the missing audiences of the otherwise overfunded organizations of the institution) and haphazard: without a targeted health strategy, these are not sufficiently effective.
Impact of environmental regulation on government subsides of public-private partnership waste-to-energy incineration projects: evidence from 66 cities in China
Authors: Shen Ye , Xu Min , Cui Caiyun , Xia Bo , Skitmore Martin , Moorhead Matthew , Liu Yong 
Published: January 2024

Introduction: Environmental regulation, as a vital component of public regulation in China, plays a crucial role in coordinating regional eco-efficiency, while the traditional hypothesis, Porter hypothesis, and uncertainty hypothesis offer three different perspectives for understanding the relationship between industry performance and environmental regulations.Methods: Based on the assumption of industry heterogeneity, 81 public-private partnership (PPP) waste-to-energy (WTE) incineration projects are analyzed using panel data from 66 cities within China during the period from 2013 to 2017 with the aims to reveal the underlying mechanism behind environmental regulation and the government subsides of public-private partnership waste-to-energy incineration projects by using multiple regression modeling.Results: The results show that the impact of environmental regulation on government subsides of PPP WTE projects has demonstrated an “Inverted-U”-shaped relationship with an inflection point, of which an increase in environmental regulation is positively correlated with an increase in subsidies at first then a negative correlation developing later.Discussion: The findings are significant in setting flexible environmental regulations according to the needs of regional economic and social development. In addition, they also supply a theoretical reference for promoting the WTE incineration industry’s sustainable and healthy development.
Comparative transcriptomic analysis of Illumina and MGI next-generation sequencing platforms using RUNX3- and ZBTB46-instructed embryonic stem cells
Authors: Póliska Szilárd , Fareh Chahra , Lengyel Adél , Göczi Loránd , Tőzsér József , Szatmari Istvan 
Published: January 2024

Introduction: We have previously observed phenotypic and developmental changes upon the ectopic expression of the RUNX3 or the ZBTB46 transcription factors in mouse embryonic stem cell (ESC) derived progenitors. In this study, we evaluated the gene expression profiles of the RUNX3- and the ZBTB46-instructed murine ESCs with RNA-seq testing two next-generation sequencing technologies.Methods: We compared the DNA nanoball-based DNBSEQ G400 sequencer (MGI) with the bridge-PCR-based NextSeq 500 instrument (Illumina) for RNA sequencing. Moreover, we also compared two types of MGI sequencing reagents (Standard versus Hot-massive parallel sequencing (MPS)) with the DNBSEQ G400.Results: We observed that both sequencing platforms showed comparable levels of quality, sequencing uniformity, and gene expression profiles. For example, highly overlapping RUNX3- and ZBTB46-regulated gene lists were obtained from both sequencing datasets. Moreover, we observed that the Standard and the Hot-MPS-derived RUNX3- and ZBTB46-regulated gene lists were also considerably overlapped. This transcriptome analysis also helped us to identify differently expressed genes in the presence of the transgenic RUNX3 or ZBTB46. For example, we found that Gzmb, Gzmd, Gzme, Gdf6, and Ccr7 genes were robustly upregulated upon the forced expression of Runx3; on the other hand, Gpx2, Tdpoz4, and Arg2 were induced alongside the ectopic expression of Zbtb46.Discussion: Similar gene expression profile and greatly overlapping RUNX3- and ZBTB46-regulated gene sets were detected with both DNA sequencing platforms. Our analyses demonstrate that both sequencing technologies are suitable for transcriptome profiling and target gene selection. These findings suggest that DNBSEQ G400 represents a cost-effective alternative sequencing platform for gene expression monitoring. Moreover, this analysis provides a resource for exploration of the RUNX3- and ZBTB46-dependent gene regulatory networks.
Next-generation sequencing testing in children with epilepsy reveals novel clinical, diagnostic and therapeutic implications
Authors: Krygier Magdalena , Pietruszka Marta , Zawadzka Marta , Sawicka Agnieszka , Lemska Anna , Limanówka Monika , Żurek Jan , Talaśka-Liczbik Weronika , Mazurkiewicz-Bełdzińska Maria 
Published: January 2024

Introduction: Epilepsy is one of the commonest diseases in children, characterized by extensive phenotypic and genetic heterogeneity. This study was conducted to determine the diagnostic utility and to identify novel clinical and therapeutic implications of genetic testing in pediatric patients with epilepsy.Methods: Large multigene panel and/or exome sequencing was performed in 127 unrelated Polish and Ukrainian patients with suspected monogenic epilepsy. Diagnostic yields were presented for five phenotypic subgroups, distinguished by seizure type, electroencephalographic abnormalities, anti-seizure treatment response, and neurodevelopmental deficits.Results: A definite molecular diagnosis was established in 46 out of 127 cases (36%). Alterations in six genes were detected in more than one patient: SCN1A, MECP2, KCNT1, KCNA2, PCDH19, SLC6A1, STXBP1, and TPP1, accounting for 48% of positive cases. 4/46 cases (8.7%) were mosaic for the variant. Although the highest rates of positive diagnoses were identified in children with developmental delay and generalized seizures (17/41, 41%) and in developmental end epileptic encephalopathies (16/40, 40%), a monogenic etiology was also frequently detected in patients with solely focal seizures (10/28, 36%). Molecular diagnosis directly influenced anti-seizure management in 15/46 cases.Conclusion: This study demonstrates the high diagnostic and therapeutic utility of large panel testing in childhood epilepsies irrespective of seizure types. Copy number variations and somatic mosaic variants are important disease-causing factors, pointing the need for comprehensive genetic testing in all unexplained cases. Pleiotropy is a common phenomenon contributing to the growing phenotypic complexity of single-gene epilepsies.