bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meios complementares de diagnóstico e terapêutica de proximidade em Cantanhede: estudo de impacto no ambiente e na sociedade
Authors: Ana Leonor Jesus  , Luís Carlos Antunes Claro  , Artur Jorge Dias Carvalhinho  , Raquel Maria Almeida Marques  
Published: December 2023

O setor dos serviços de saúde apresenta múltiplos aspetos ambientais que podem resultar em impactos negativos significativos no ambiente e na saúde humana. Aqui, incluem-se as emissões de poluentes de forma direta (por exemplo, através dos resíduos hospitalares gerados) e de forma indireta (como é o caso das emissões de gases com efeito de estufa relativas ao setor dos transportes, tanto por parte dos colaboradores como dos utentes destes serviços, que efetuam centenas de viagens diárias na procura de cuidados médicos, devendo estas ser sempre contabilizadas.
Os veículos movidos a combustível fóssil, durante a sua utilização no quotidiano, são um dos grandes proporcionadores do aquecimento global e da emissão de poluentes nocivos, que comprometem a saúde de quem está sujeito à sua exposição. É urgente, portanto, adotar medidas que visem a redução e mitigação desta problemática, garantindo a saúde das populações e o equilíbrio dos ecossistemas que as rodeiam.
Assim, com este estudo, procuramos detalhar os impactos do setor da saúde, ambiente e na sociedade, com enfoque na maioridade da população abrangida pelo Hospital Arcebispo João Crisóstomo de Cantanhede (idosos e utentes com mobilidade condicionada), com realização de um estudo de caso aplicado a um hospital “amigo dos + velhos”, onde se integram os meios complementares de diagnóstico e terapêutica de proximidade, que são realizados com apoio de um veículo elétrico para deslocação dos prestadores de cuidados às diferentes unidades da área de abrangência.
Destacam-se, ainda, os impactos na sociedade, relacionados com a deslocação de pessoas mais velhas, focando a implementação deste projeto numa perspectiva comunitária abrangente.
Os idosos enquanto cidadãos de pleno direito: Breve abordagem acerca da tutela internacional e constitucional dos Direitos dos Idosos
Authors: Joana Oliveira da Silva Aroso Marques  
Published: December 2023

Cientes de que a longevidade se afigura, atualmente, como um facto incontornável e como uma inegável conquista civilizacional, importa cada vez mais refletir acerca do enquadramento dos direitos dos idosos como direitos humanos, quer no plano Internacional quer no plano nacional, fazendo uma breve análise crítica das Convenções existentes e da Constituição da República Portuguesa.
Pensar juridicamente a condição dos mais velhos, enquanto cidadãos de pleno direito, livres de desenvolver a sua personalidade e de envelhecerem com dignidade, autonomia e de modo ativo e saudável, é o desafio a que nos propomos, focando os vetores essenciais da aprendizagem ao longo da vida e do paradigma residencial como aspetos fundamentais para que tal desenvolvimento ocorra.
A abordagem do tema na perspetiva do exercício da cidadania visa, numa lógica de capacitação, trazer para o espaço público, que lhes é devido, os “novos idosos” que o progresso científico e económico nos permite hoje, conhecer, e um dia vir a ser, na expectativa de que a sua e a nossa voz ativa retire da invisibilidade aqueles que, por alguma razão, se encontrem em situações de maior vulnerabilidade, fragilidade ou solidão.
Alto Minho + Inclusivo para um envelhecimento ativo e saudável: diagnóstico orientado para as comunidades ERPI com o Protocolo MAIEC©
Authors: Odete Maria Azevedo Alves  , Pedro Miguel de Almeida Melo  , Paula Clara Ribeiro Santos  , Laura da Conceição Mendes de Brito  , Olga Fernandes Franco Rodrigues  , Maria da Graça Netto Lima da Silva Pereira Ferro  , Nádia Verónica Sampaio Andrade  , Pedro Maciel Barbosa  , Cláudia Telles de Freitas  , Rui Pedro Teixeira Ferreira da Silva  
Published: December 2023

O projeto “Alto Minho + Inclusivo para um envelhecimento ativo e saudável" trata-se de uma iniciativa conjunta entre entidades públicas e de solidariedade social do Alto Minho e conta com o envolvimento ativo da comunidade. Através de uma abordagem colaborativa e participativa, pretende criar um ambiente favorável à promoção da saúde e bem-estar da população idosa, contribuindo assim para uma sociedade mais inclusiva e coesa.
Pretende avaliar o Empoderamento comunitário e a Gestão comunitária como estratégias para garantir a participação ativa dos idosos e colaboração das instituições.
O Modelo de Avaliação e Intervenção em Enfermagem Comunitária (MAIEC©) é utilizado para entender as necessidades de saúde das comunidades, incluindo análise das populações, recursos locais, condições ambientais e sociais que afetam a saúde comunitária. Através de grupos focais com líderes/membros da comunidade foi avaliado o Empoderamento comunitário e com a aplicação de um questionário foi efetuado o diagnóstico da Gestão comunitária.
Em termos de diagnóstico da Gestão comunitária para a promoção do envelhecimento ativo e saudável das pessoas idosas residentes em Estrutura Residencial para Pessoas Idosas, verifica-se que a Liderança comunitária – subdimensão “Conhecimentos”, Participação comunitária e Processo comunitário se encontram comprometidos. Quanto ao nível do Empoderamento comunitário, constatam-se seis domínios com score inferior a 2, comum a mais do que uma comunidade.
No Empoderamento comunitário, existem domínios suscetíveis de serem melhorados e a Gestão comunitária está comprometida. Torna necessário a implementação de um programa de intervenção multidisciplinar focado na promoção do envelhecimento ativo e saudável, considerando as comunidades como unidade de cuidados.
ArreVita – Programa de Estimulação e Reabilitação Neurocognitiva (Estudo Piloto)
Authors: Cristiana Filipa da Silva Pereira de Sousa  , Renato Leonel Barbosa Gomes  
Published: December 2023

A presença de uma Lesão Neurológica Adquirida compromete o desempenho das ocupações significativas do Ser Humano. A Neuroplasticidade representa a faculdade do cérebro para recuperar-se e reestruturar-se. Este potencial adaptativo do sistema nervoso permite ao cérebro recuperar de transtornos ou lesões.
Este estudo deteve como objetivos avaliar a eficácia da implementação de um programa de estimulação e reabilitação neurocognitiva, em pessoas internadas numa unidade de cuidados continuados de média duração e reabilitação, com alterações no desempenho cognitivo resultantes de uma multiplicidade de situações.
A amostra é constituída por 107 indivíduos, com idades compreendidas entre 37 e os 97 anos, com uma média de idade de 72 anos. Foi usado como metodologia de conhecimento os resultados obtidos na Medida de Independência Funcional (MIF), nomeadamente os valores da vertente cognitiva, na Admissão e na Alta. O programa desenvolveu-se através de intervenção em grupo, 2/semana, com a duração de 60 minutos.
Os resultados demonstraram um aumento médio de 10% nos valores obtidos na Vertente Cognitiva da MIF, refletindo o melhoramento médio de um nível de dependência da MIF. Comparativamente aos valores obtidos em ano anterior, sem a aplicação do programa, verificou-se um aumento nos resultados atingidos.
Através do presente estudo foi possível verificar a eficácia da implementação de um programa de estimulação e reabilitação neurocognitiva, em grupo, na diminuição do défice cognitivo decorrente de uma Lesão Neurológica Adquirida.
Smart Agriculture: Technologies, Practices, and Future Directions
Authors: Kiran  , Saikanth D. R. K. , Saikia Anadi Ranjan , Chintey Rajesh , Talukdar Nilabh , Bahadur Raj , Vasuki A. 
Published: December 2023

The Internet of Things (IoT) has ushered in a new era of innovative agriculture research. Because IoT is still in its early stages, it must be widely tested before it can be widely deployed in many agricultural applications. In this paper, I look at different prospective IoT applications, as well as the unique concerns and constraints connected with IoT deployment for better farming. The gadgets and wireless communication technologies linked with IoT in agricultural and farming applications are thoroughly researched to focus on the unique requirements. Sensor-enabled IoT systems that deliver intelligent and smart services for smart agriculture are being investigated.
Several case studies are offered to investigate the existing IoT-based solutions implemented by various organizations, individuals, and groups depending on their deployment criteria. The difficulties in these solutions are addressed, as are the factors for improvement and the future roadmap of work with IoT. Smart farming is a trend that emphasizes the use of information and communications technology (ICT) in machinery, equipment, and sensors in network-based hi-tech farm supervision cycles. Innovative technologies such as the Internet of Things (IoT) and cloud computing are expected to spur growth and kickstart the usage of robotics and artificial intelligence in agriculture. Such radical departures are upsetting established agricultural practices while also posing several obstacles. This study explores the techniques and equipment utilized in wireless sensor applications in IoT agriculture, as well as the predicted problems encountered when integrating technology with traditional farming practices. Furthermore, this technical knowledge is useful to growers during crop times ranging from planting to harvest, and applications in packing and transportation are being researched.
Popping patterns in F2 segregant progenies from popcorn × non-popcorn crosses
Authors: Trejo-Pastor Viridiana , Santacruz-Varela Amalio , Córdova-Téllez Leobigildo , López-Sánchez Higinio , Costich Denise E. , Díaz-Juárez Roberto de la Cruz 
Published: December 2023

The most important commercial feature in popcorn (Zea mays L.) is the expansion of the starch contained in the endosperm; however, little has been studied about the underlying genetic basis of this quantitative trait, for which the development of segregating populations is required. The first step is the selection of the most appropriate contrasting parents for popping capacity to create these populations. The objectives of this study were, 1) to analyze the popping patterns of F2 populations derived from crosses between popcorn × nonpopcorn inbred lines to identify the most divergent cross for future molecular analysis in search of alleles-related to popping capacity, and 2) to estimate the number of genes responsible for popping expansion volume based on the tails of segregation. Seven biparental crosses of popcorn × non-popcorn were performed to obtain F2 populations, and those were phenotypedfor popping expansion volume. Phenotypes were analyzed by the H test, Lilliefors normality-test, Fisher’s coefficient of skewness, and kurtosis level. The number of genes estimation was made with X2 and (1/4)n tests. The popping patterns indicated that popcorn × flint corn was the most divergent cross, with the most symmetrical distribution, and therefore, the best suitable population to be used for molecular analysis. Results indicated the existence of three to five major genes related to popping expansion volume. Transgressive segregation was present in all populations, showing individuals whit a popping expansion volume higher or lower than the parental ones, suggesting that non-popcorn lines contain variation for alleles that promote popping.
Keywords: Popcorn, popping expansion volume, popping patterns, transgressive segregation, Zea mays L.
Use of nurse endosperm for the culture of haploid embryos produced by durum wheat x maize crosses
Authors: Sahli Anissa , Ltifi Ali , Mansouri Sonia , Haouala Faouzi 
Published: December 2023

The use of doubled-haploids in plant breeding programs enables accelerating the release of new varieties adapted to climate change. The durum wheat x maize crosses technique is a method of choice for producing durum wheat haploid plants. The haploid embryos produced by this method develop without albumen and their survival is ensured by post-pollination hormonal treatments. In this study, nine post-pollination treatments with 2,4-Dichlorophenoxyacetic acid (2,4-D), Picloram and Dicamba at the concentrations of 10, 50 and 100 mg.L-1 were applied to 7 durum wheat genotypes. The effects of genotype and post-pollination treatment on durum wheat haploid embryos produced by durum wheat x maize crosses and the use of the endosperm nursing technique for haploid plantlets regeneration were investigated. The haploid induction parameters varied with the durum wheat genotypes as well as the post-pollination treatments. The phenomenon of polyembryony resulting from durum wheat x maize crosses is reported for the first time in this article. The durum wheat genotypes showed different abilities to produce monoembryo and polyembryos. The post-pollination treatments with 2,4-D (10 mg.L-1) and Picloram (10 and 100 mg.L-1) gave a higher embryo formation frequency than the treatments with Dicamba. The embryo conversion to plantlet was greatly improved, especially in recalcitrant genotypes using the durum wheat endosperm as supplemental nourishment in combination with the Gamborg B5 regeneration medium.
Keywords: Durum wheat; Haploid embryo; Maize; Nurse Endosperm Technique; Polyembryony
Vitis vinifera L. variety Syrah sprayed with ZnSO4: Effect on fruit quality and winemaking
Authors: Daccak Diana , Luís Inês Carmo , Marques Ana Coelho , Pessoa Cláudia Campos , Coelho Ana Rita F. , Galhano Carlos , Silva Maria Manuela , Legoinha Paulo , Simões Manuela , Reboredo Fernando H. , Lidon Fernando C. , Scotti-Campos Paula , P. Pais Isabel , Ramalho José C. , E. Leitão António 
Published: December 2023

In grapevines, Zn is essential for normal leaf growth, shoot elongation and pollen development, allowing a fully developed berry. In this context, using as a test system Vitis vinifera L. variety Syrah, this study aimed to assess the interactions between Zn enrichment in grapes and sugars and fatty acids profiles, further considering the sensory implications of red wine production. Vineyard conditions of the soil were assessed to ensure the natural optimal development of grapevines and the workflow for Zn enrichment considered three treatments: foliar spray with water (control) and with ZnSO4 (at 450 and 900g.ha-1). After the 2nd foliar application of ZnSO4, only minor changes of Zn, Ca and P contents were found in grapes (the levels of K, Cu and S increased significantly with ZnSO4 (450 g.ha-1). At harvest, the grapes submitted to foliar application of ZnSO4 showed significantly higher levels of Zn (between 33.38 - 54.41%), but significant deviations in sugars (sucrose, glucose and fructose), fatty acids (C18:0, C18:1, C18:2, C18:3, C16:0, C<16:0) and color parameters were not found. After winemaking, relative to the control, a higher content of Zn persisted (60.59 - 63.82%), without impairing the characteristics desired by consumers. In fact, the wine with ZnSO4 (900 g.ha-1) was the most sensorially accepted.
Keywords: Foliar spraying with ZnSO4; Grapes enrichment with Zn; Nutrient’s interactions; Sugars and fatty acids profiles; Vitis vinifera L. variety Syrah; Winemaking.
Genetic gain and selection of stable genotypes in high zinc rice using AMMI and BLUP based stability methods
Authors: Behera Partha Pratim , Sivasankarreddy Kasireddy , Reddy Bodeddula Jaysankar , Saharia Niharika , Sarma Ramendra Nath , Singh Shravan Kumar , Majhi Prasanta Kumar , Borah Nayanmoni 
Published: December 2023

Rice is the staple food of almost half of the world’s population, impacting nutrition especially in children, pregnant women, and nursing mothers. Because the traits were quantitatively inherited, they are affected by changes in location and year. A RBD with three replications was used to identify superior and stable high-zinc rice genotypes in Uttar Pradesh, India. Grain zinc content (GZC) is negatively correlated with grain yield using genetic association study. There was a significant G × E interaction (GEI) and V16 and V21 for GYP and V9, V2 and V10 for GZC were identified as stable based on the AMMI model and bi-plot. V11, V5, V21 for grain yield per plant (GYP) and for GZC, V14, and V10 are found to be stable and common in all AMMI stability parameters. V6, V13 and V5 for GYP and V10, V8 and V2 for GZC were identified as stable based on the mean vs. WAASB bi-plot. V21 for GYP and V4 for GZC was the highest yielder and widely adaptable based on WAASBY scores. V13 for GYP and V1 for GZC were all-time winners. V13 and V1 have the highest predicted mean for GYP and GZC, respectively, based on BLUP. V6, V21and V13 were identified as stable and selected based on the multi-trait stability index (MTSI). These selected genotypes selected through BLUP-based stability methods, MTSI, and strength and weakness plots make it easier to evaluate and select genotypes for varietal recommendations and future Zn-fortified rice breeding studies.
Keywords: GEI, High Zinc Rice, MTSI, Stable genotype
Polyphenol galangin induces the ROS and ER stress-mediated intrinsic and extrinsic apoptotic pathways towards human colon carcinoma HCT-116 cells
Authors: Miranda Ina Ramírez , Betancur Ancona David , Ordóñez Yolanda Moguel 
Published: December 2023

The Melipona beecheii honey has bioactive compounds with high antioxidant activity that influence its colour. This research evaluated the influence of phenolic compounds and flavonoids on the colour and antioxidant activity of M. beecheii honeys. Forty-three honey samples from different site located in the low deciduous forest of Yucatan, Mexico, were extracted during the harvest and post-harvest seasons (2020 – 2021). The Pfund method was used to measure colour, Folin-Ciocalteu method for phenols measurement, aluminum chloride method for flavonoids determination, and ABTS and DPPH IC50 assay to determine antioxidants. The predominant colour of the honey was extra light amber and light amber at both seasons. Phenols ranged from 780 to 1317 mg/kg GAE; flavonoids from 36 to 55 mg/kg CE and antioxidant were 675 to 1161 µmol/kg TEAC by the ABTS and 361.8 to 173.0 mg/mL by the DPPH IC50. Phenols and flavonoids were correlated with colour and radical scavenging activity, indicating the influence of these compounds with the darker colour and higher antioxidant activity of honey. The statistically significant difference (P<0.05) between seasons could be associated with the botanical origin with great diversity of melliferous flora present in the low deciduous forest of the Yucatan Peninsula.
Keywords: Antioxidant; colour; flavonoids; honey; Melipona beecheii.
Bacillus megaterium Compensates for Growth Inhibition from Phosphorus Deficiency by Improving Photosynthetic Capacity, Changing Antioxidant Potential, and Regulating Non-Structural Carbohydrate Concentrations in Glycyrrhiza uralensis
Authors: Zhang Yali , Gao Jing , Li Rui , Yan Yonggang , Zhang Gang , Wang Nan , Wang Wenbo , Yan Jiakun 
Published: December 2023

This study assessed the effect of Bacillus megaterium on seedling growth of Glycyrrhiza uralensis Fisch. under control and phosphorus (P) deficiency conditions. The results showed that P deficiency improved 1) G. uralensis root growth, 2) superoxide dismutase, catalase, and peroxidase activities, 3) inorganic P, starch, and soluble sugar contents in roots, 4) dissipated energy flux per reaction center, trapped energy flux per reaction center, and absorption flux per reaction center, and 5) net photosynthetic rate, stomatal conductance, transpiration rate, maximum fluorescence intensity after dark adaptation, and variable fluorescence. However, P deficiency significantly decreased chlorophyll and carotenoid contents in G. uralensis, but enhanced chlorophyll and carotenoid contents in B. megaterium. Our findings on the regulatory mechanisms of B. megaterium in response to P starvation hold promise for improving the success of G. uralensis cultivation.
Keywords: Bacillus megaterium; Glycyrrhiza uralensis Fisch; Phosphorus deficiency; Chlorophyll fluorescence; Antioxidant enzymes superoxide; Non-structural carbohydrate
Sweetener Food Additives: A Synoptical Overview on Their Chemical Properties, Applications in Food Products and Side Effects
Authors: Silva Maria Manuela , Reboredo Fernando Henrique , Lidon Fernando Cebola 
Published: December 2023

The increase of obesity and its metabolic comorbidities have led to a growing consumption of sugar-free products, where sucrose is replaced by low-calorie sweeteners. Since the discovery of the synthesis of saccharin, progressively more non-nutritive sweeteners have been produced and consumed, as they release none or only very small amounts of energy. In this context, traditional synthetic food sweeteners are largely used, because they have a higher sweetener power than most of the sweeteners of natural origin. Yet, due to their potential risks, some of them are being replaced by those obtained from natural origins with high sweetening power, such as thaumatins and neohesperidin DC, or by synthetic sweeteners with an even greater sweetener power, with advantame as the one with the highest sweetening power. Yet, numerous side effects of synthetic sweeteners have been reported (namely, stomach and liver problems, allergic reactions, nausea, vomiting, changes in behaviour, cognitive problems, genotoxicity and carcinogenic effects), whereas those naturally derived seem to have less important health problems associated. Moreover, some sweeteners of natural origin, such as polyols, have a low sweetening power, which makes them less effective, but have other functions in food processing. To further understand the implications of using synthetic and natural-derived food sweeteners, this review aims to provide a synoptical approach on chemical characteristics, properties, uses and side effects of those which are currently allowed and applied during food processing mostly considering the authorized sweeteners in European Union.
Keywords: Side effects of sweeteners; Sweetener food additives; Sweeteners of natural origin; Sweeteners of synthetic origin; Sweeteners applications
Filamentous‐Actin‐Mimicking Nanoplatform for Enhanced Cytosolic Protein Delivery
Authors: Xia Yuqiong , Wu Keyun , Liu Chang , Zhao Xuejuan , Wang Jun , Cao Jianxia , Chen Zhaoxu , Fang Minchao , Yu Jie , Zhu Cheng , Zhang Xianghan , Wang Zhongliang 
Published: December 2023

AbstractDespite the potential of protein therapeutics, the cytosolic delivery of proteins with high efficiency and bioactivity remains a significant challenge owing to exocytosis and lysosomal degradation after endocytosis. Therefore, it is important to develop a safe and efficient strategy to bypass endocytosis. Inspired by the extraordinary capability of filamentous‐actin (F‐actin) to promote cell membrane fusion, a cyanine dye assembly‐containing nanoplatform mimicking the structure of natural F‐actin is developed. The nanoplatform exhibits fast membrane fusion to cell membrane mimics and thus enters live cells through membrane fusion and bypasses endocytosis. Moreover, it is found to efficiently deliver protein cargos into live cells and quickly release them into the cytosol, leading to high protein cargo transfection efficiency and bioactivity. The nanoplatform also results in the superior inhibition of tumor cells when loaded with anti‐tumor proteins. These results demonstrate that this fusogenic nanoplatform can be valuable for cytosolic protein delivery and tumor treatment.