bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and Failure Stress Analysis of Crane Hook by Using Mesh Sensitivity Analysis Approach on Finite Element Method
Authors: Zeleke Zablon , Tamiru Tesfaye , Ashuro Belachew , Bogale Dilnesaw 
Published: December 2023

Abstract
In realistic applications, crane hooks are used mostly under high loading conditions and subjected to high-stress concentrations which cause failure of these material handling equipment. Failure mainly occurs due to high-stress concentration on the hook at a specific point. Determining these maximum stress concentrations that cause failure and the point where they occur is vital in reducing the failure of hooks. Therefore, FEM analyses are useful for obtaining an understanding of stress concentration on hooks that lead to failure. In this study, both analytical and numerical analyses were performed on the hook which is subjected to a vertical load of 50ton (490.5kN) for specifically selected hook material. The maximum stress resulting from analytical calculations is 1410.1MPa, which is safe as compared to the yield strength of hook material. The maximum Von Mises stress, maximum principal strain, and total deformation of hook were determined by numerical method. To produce more reliable results numerically on ANSYS Workbench 19.2 mesh sensitivity analysis (MSA) was performed. The meshing size dependence of maximum stress was studied by refinement of meshes. From the convergence study, the maximum failure stress determined is 1412.4MPa, which is also safe as compared to the yield strength of the material. Even if there are some variations in the results of analytical and numerical approaches, both results are safe for the loading condition of the crane hook.
Risk, predictive factors and Nomogram of liver metastatic gastroesophageal junction cancer: A new study based on SEER Database
Authors: Tian chenrui , Li yang , Li Min 
Published: December 2023

Abstract
Purpose of the study:
Liver metastases were common in gastroesophageal junction cancer (GEJ) patients with poor prognosis. Using the Surveillance, Epidemiology, and End Results (SEER) database, the present study investigated the incidence, risk, and prognostic factors of liver metastases in GEJ patients diagnosed between 2010 and 2019 from the SEER database.
Study design:
The univariable and multivariable logistic and Cox regression models were used to investigate the risk factors for liver metastase development and prognosis, respectively. The liver metastases predicting nomograms were constructed, evaluated. The overall survival (OS) of patients with liver metastases was analyzed by the Kaplan–Meier method.
Results
Finally, a total of 8,197 eligible GEJ cancer patients were included and 1,558 of them were diagnosed with liver metastases. The median survival of the liver metastatic GEJ cancer patients was about 5 months. Age, TN stage, surgery, radiation, and regional lymph node dissection were significantly associated with liver metastases occurrence. The calibration curve and C-index exhibited good performance of the nomograms for predicting GEJ cancer patients.
Conclusions
The nomograms were expected to be effective tools for predicting the risk of liver metastases for GEJ cancer patients which may benefit clinical decision-making.
Word Count:
Liver metastases in GEJ tumors may remain asymptomatic in the early stages. Timely recognition of these symptoms is vital for early intervention. The three-year prognosis for gastroesophageal junction cancer with liver metastasis is unfavorable, and the associated risks warrant further investigation. In this study, our risk and prognosis model for predicting GEJ tumors with liver metastasis is anticipated to serve as an effective tool.
Hierarchical Chitosan/Carbon Composites for Enhancing Electricity Generation Performance of Geobacter sulfurreducens
Authors: Gao Sheng-Chao , Zhou Wen , Mai Ting-fang , Zhang Yue , Li Yuxuan , Gao Tian-peng , Liu Ying 
Published: December 2023

Abstract
Two types of chitosan/carbon composites including chitosan/carbon nanotubes (CS/CNTs) and chitosan/carbon black (CS/CB) were utilized to modify graphite electrode for the electrochemically active biofilm (EAB) growth of Geobacter sulfurreducens. The hierarchically novel carbon composites modified electrodes have been obtained via facile vacuum freeze-drying. CS/CNTs (5 h) showed porous structure and CS/CB (5 h) exhibited the lamellar structure. Compared with the control, the maximum current densities of EAB growth on the CS/CNTs (5 h) increased by 135%, CS/CNTs (10 h) with longer time only increased by 56%. Unexpectedly, the EAB growth on CS/CB (5 h) modified electrode showed relatively better performance than that of CS/CNTs (5 h) increasing by 16.7%. In addition, CS/CB (10 h) modified electrode increased by 48.9% comparing with CS/CNTs (10 h). It can be seen that the CS/CB with 5 h freeze-drying possessed a better characteristic structure for promoting EAB growth and enhancing performance.
Design for Assembly &amp; Armoring (DfA2) Methodology for Passenger Vehicle Protection Operations – Case Study Applied to a Front Door Assembled
Authors: Candido Guido Muzio , Kaminski Paulo Carlos 
Published: December 2023

Abstract

The personnel protection market of civilian armored vehicles (CAVs) continually grows in emerging countries. Therefore, this article proposes a Design for Assembly and Armoring, DfA2 methodology for the lightweight ballistic protection operations of CAVs based on real practical situations showing the main difficulties and best practices of current armoring operating conditions. A bibliographic review focused on Design for Excellence (DfX) and automotive and ballistic protection design criteria were performed to introduce the base of the DfA2 proposal and apply it to a front door assembly case study, including CAD/CAE interface analysis. The authors presented the detailed armoring flow of the front door system using the DfA2 method. In addition, strategical cross sections showed critical areas of the referred assembly. The opaque and transparent armor parts installed comply with the NIJ-IIIA ballistic protection level. The DfA2 method provided meaningful automotive and ballistic considerations to integrate protection parts in the front door system. In addition, it proposed to conduct and spread the best practices for operation guidelines and procedure standards related to CAVs on shop floors. Furthermore, the DfA2 methodology intends to preserve the original functionalities and guarantees automobiles for consumers. The article integrates the practical operations of armoring companies with DfX tools and automotive and ballistic guidelines, all of which are incorporated in the DfA2.
An Adaptive Ensemble YOLOX Model with Roulette-based Re-sampling Strategy for Traffic Sign Detection and Recognition
Authors: Hu Rong , Zhang Ming , Chen Dequ , Xu Yong 
Published: December 2023

Abstract
As one of the key technologies for autonomous driving, traffic sign detection and recognition (TSDR) remains a challenging task due to the difficulty and complexity of traffic signs. Moreover, real-world traffic signs exhibit a long-tailed distribution (i.e., data for most categories are scarce while others are abundant), which has negative impact on the detection model. In this paper, we propose a novel model to tackle these challenging problems. Two adaptive copy-paste methods are proposed for the long-tailed data problem to expand the tail categories efficiently. To detect difficult traffic signs, we propose roulette-based re-sampling to emphasis on data of difficult categories. Furthermore, an adaptive ensemble YOLOX model with double-level head is proposed which adaptively assembles hierarchical head that emphasizes features at different levels by learning the feature representation of level-aware traffic signs. An adaptive class box fusion module is utilized to further improve the ensemble efficiency. Extensive experiments on TT100K and Comprehensive TT100K datasets show that the method proposed in this paper achieves significant improvements in both difficult traffic signs and alleviates long-tailed data problems. It can effectively improve the miss-detection problem of difficult traffic signs and meet the TSDR requirements of real-time and high accuracy.
“I want one nurse who is friendly to talk to me properly like a friend”: Learner preferences for HIV and contraceptive service provision in Gauteng, South Africa
Authors: Moolla Aneesa , Constance Mongwenyana , Ngcobo Nkosinathi , Mngadi Sithabile , Govathson Caroline , Long Lawrence , Pascoe Sophie Jane 
Published: December 2023

Abstract

Background
Research with adolescents indicates that youth aged 15–24 years, especially females, are at high risk for HIV infection. The overall HIV prevalence among youth in this age group was 6.2% estimated in 2022. In addition, > 800,000 adolescents are newly infected with HIV every year and 79% of these infections occur in sub-Saharan Africa. The health service provision preferences and needs of adolescents are critical to reaching this population.
Methods
This qualitative study was conducted with learners from three public secondary schools in Gauteng, South Africa. Using convenience sampling, 22 in-depth stakeholder interviews (KIIs) with stakeholders and 8 focus group discussions (FGDs) with 55 learners aged ≥ 15, were conducted between March and October 2018. Learners < 18 were given assent and parental consent forms, whilst those ≥ 18 could consent of their own accord. KIIs and FGDs were conducted in private venues in the preferred language by trained interviewers and audio-recorded. Audio files were transcribed verbatim and translated into English if needed. Data were analysed thematically using NVivo version 11.
Results
The findings from both stakeholders and learners indicate many critical accessibility barriers which include: negative healthcare staff attitudes from older judgemental staff; stigmatisation from healthcare workers, the community as well as family; a lack of private consulting spaces and no confidentiality of patient information at facilities; inconvenient clinic operating times; long queues and facility resource issues. Both groups of participants suggested that accessibility to healthcare could be improved through value-added services (including free Wi-Fi and food), social gatherings and educational information sessions, as well as being staffed by younger, friendlier, confidential and non-judgemental staff in a private healthcare setting.
Conclusion
It is clear that there are many critical barriers that deter learners from accessing HIV and contraceptive services. Provision of private rooms and trying to ensure information confidentiality for youth-friendly services at locations and times that can be easily accessed by learners is key. Greater emphasis on learner-parent-teacher communication around sexual health education at school is needed along with making this information being more readily available to learners.
Delving potentials of direct and indirect selection parameters in segregating generation differing for stem growth habit in chickpea
Authors: Ambika Ambika , Kumar Rajendra 
Published: December 2023

Abstract

Chickpea (Cicer arietinum L.) is predominantly an indeterminate (IDT) plant and tends to generate vegetative growth when the soil is conducive for soil moisture, temperature, and certain other environmental conditions. The semi-determinate (SDT) types are comparatively early, resistant to lodging and found to be similar in their yield potential to IDT lines. Thus, knowledge on genetic variations for pod and seed traits of different stem growth habit is important. The present study aims to estimate genetic variability and relation between yield and its related attributes of segregating population of chickpea. Variability studies were studied in BGD 362 (IDT) x BG 3078-1(SDT) cross differing for stem growth habit. Wide range of variation was reported for the trait plant height, pods per plant, seeds per plant, seed yield and 100-seed weight. Pods per plant showed high PCV and GCV. Pods per plant, seeds per pod, seed yield, and 100 – seed weight recorded high heritability coupled with high genetic advance. Seed yield per plant has shown highly significant positive association with seeds per plant, pods per plant, and 100 – seed weight. The pods per plant had high positive indirect effect on seed yield per plant indicating that selection for plant types with a greater number of pods per plant will be effective in the simultaneous improvement of seeds per plant and sustainable grain yield in chickpea.
The Mechanism of Isoproterenol Hydrochloride-Induced Cardiac Arrhythmia and the Effect of Propranolol Through the CaMKII Pathway
Authors: Ma Guoping , Ma Kexin , Li Mian , Liang Ruijing , Guo Zijing , Xiao Yupeng , Liu Gang , Liang Wenjie 
Published: December 2023

Abstract
Background
Ventricular arrhythmia (VA) is a common clinical disease that is associated with high morbidity and mortality. Calcium/calmodulin-dependent protein kinase II (CaMKII) is critical in regulating cardiac electrophysiological functions. Research shows that propranolol can significantly antagonizes VA. However, it is unclear whether propranolol can regulate CaMKII, thereby inhibiting VA.
Aims
The present study aimed to clarify the molecular mechanism by which propranolol inhibits VA through the CaMKII pathway.
Methods
A total of 60 healthy Sprague Dawley rats were randomly divided into the control and experimental groups (model and propranolol group) that were given corresponding treatment. Isoproterenol hydrochloride (ISO) was administered to induce VA. The ECG was monitored for 1 hour, and the VA incidence was calculated. The heart weight/body weight (HW/BW) ratio was calculated manually. The levels of Ca2+, cTnI, oxidative stress, Inflammatory factors were studied.Calcium pump (SERCA2) and CaMKIIδ mRNA were detected by Real-time PCR. Western blotting was used to assess CaMKII, oxidized CaMKII (OX-CaMKII), phosphorylated phosphoprotein (P-PLB) and SERCA2.
Results
There was no obvious abnormality in the control group. Compared with the control group rats, the indexes of rats in model group changed significantly (P < 0.01). Compared with the model group rats, the indexes of rats in the propranolol was significantly improved (P < 0.01 or P < 0.05 ).
Conclusions
Collectively, propranolol antagonized VA effect by reducing CaMKII expression and activating SERCA2, thereby reducing the Ca2 + load .
Quantum homomorphic aggregate signature based on quantum Fourier transform
Authors: Chen Teng , Lu Dian-Jun , Deng Zhi-Ming , Yao Wei-Xin 
Published: December 2023

Abstract
With the rapid development of computer and internet technology, quantum signature plays an extremely important role in modern secure communication. Quantum homomorphic aggregate signature, as an important guarantee of quantum signature, plays a significant role in reducing storage, communication, and computing costs. This article draws on the idea of quantum multi-party summation and proposes a quantum homomorphic aggregate signature scheme based on quantum Fourier transform. Our scheme uses $n$-particle entangled states as quantum channels, with different particles of each entangled state sent separately. This ensures secure transmission of signatures and messages with fewer entangled particles during transmission, further improving the efficiency of quantum signatures. Meanwhile, our scheme generates private keys for each participating party by randomly constructing key generation matrixes. Different signers perform quantum Fourier transforms and basis exchange operations on entangled particles based on different messages and private keys to generate signatures. In addition, the aggregator does not need to measure and verify the signature particles after receiving signatures from different signers, and the group addition operation process has additive homomorphism. Security analysis shows that our scheme has unforgeability, non-repudiation, and can resist various attacks such as entanglement measurement attacks, intercept-resend attacks, private key sequence attacks, and internal attacks by aggregator.
Duffin-Kemmer-Petiau oscillator in topologically charged Ellis-Bronnikov-type wormhole
Authors: Aounallah Houcine , Moussa Abbad , Ahmed Faizuddin , Rudra Prabir 
Published: December 2023

Abstract

In this study, we study the relativistic quantum dynamics, specifically focusing on a spin-0 system described by the Duffin-Kemmer-Petiau (DKP) equation within the context of an Ellis–Bronnikov-type wormhole endowed with topological charge. Our objective is to find the solution to the DKP equation, which, notably, takes the form of the Heun differential equation. Through this investigation, we ascertain the ground energy levels associated to this system. Furthermore, we extend our exploration to the DKP oscillator and employ a similar methodology to derive the ground state energy levels of the oscillator field. In addition, we introduce an electromagnetic four-vector potential and study the DKP oscillator in the wormhole background. An intriguing aspect of our findings lies in the influence of the wormhole's non-trivial topology as well as external potential on the energy levels of this relativistic quantum system.
PACS numbers: 03.65.Vf, 11.30.Qc, 11.30.Cp
Add-on multidrug therapy based on quadruple therapy successfully treated worsening heart failure caused by　anthracycline-induced cardiomyopathy in a young adult cancer survivor: a case report
Authors: Oda Hirotaka , Hayashi Yuka , Oyanagi Norihito , Tanaka Komei Tanaka , Ozaki Kazuyuki , Tsuchida Keiichi , Kashiwa Asami , Hosaka Yasuo , Takahashi Kazuyoshi 
Published: December 2023

Abstract
Background In patients with heart failure and a reduced ejection fraction, the overall mortality and morbidity benefit is greatest when treated with the combination of sacubitril/valsartan, beta-blockers, mineralocorticoid-receptor antagonists, and sodium-glucose transporter-2 inhibitors, the so-called "fantastic four" or "quadruple therapy.” Adding vericiguat (an oral soluble guanylate cyclase stimulator) is thought to aid in the management of worsening heart failure after quadruple therapy. Among children and young adult cancer survivors, cardiovascular complications that develop more than ten years after anthracycline-based chemotherapy have a poor prognosis. The efficacy of multidrug therapy based on quadruple therapy for worsening heart failure among cancer survivors with anthracycline-induced cardiomyopathy has not been reported.Case Presentation A young adult cancer survivor who had undergone high-dose anthracycline chemotherapy experienced acute decompensated heart failure 20 years post-chemotherapy and developed worsening heart failure one and a half years after discharge. Initiation of quadruple therapy with necessitous ivabradine induction for the worsening heart failure demonstrated a trend toward improvement. Vericiguat was accelerated because of the risk of more severe cardiovascular events associated with ongoing aortic stenosis and the poor prognosis of anthracycline-induced cardiomyopathy. Heart failure symptoms continued to improve with significant cardiac reverse remodeling, and the patient successfully underwent aortic valve replacement for severe aortic stenosis.Conclusions Multidrug therapy with add-on vericiguat and ivabradine based on quadruple therapy may successfully treat worsening heart failure among high-risk cancer survivors with severe anthracycline-induced cardiomyopathy.
Integrated Crayfish waste-shells valorization for added value materials production: Calcium Hydroxide, Calcium Carbonate, Chitin, Chitosan, and N/S@Carbon quantum dots
Authors: Giannakas Aris E. , Georgopoulos Stavros , Leontiou Areti , Sakavitsi Viktoria , Cheilari Antigoni , Kollia Eleni , Zaharioudakis Konstantinos , Ragkava Efthymia , Karabagias Vasilios K. , Andritsos Nikolaos D. , Konstantinou Ioannis , Proestos Charalampos , Kehayias George , Salmas Constantinos E. 
Published: December 2023

Abstract
Food waste and byproducts landfilling practice produce remarkable amounts of hazardous gasses and substances due to the anaerobic decomposition process. Vertical integration of production and waste valorization are two of the methods adopted globally to reduce food waste following the circular economy and environmentally friendly practices spirit. In this study an integrated procedure is proposed for the valorization of wastes produced by a fish and crustaceous enterprise. Calcium hydroxide particles of size 6.32 µm and Calcium carbonate particles of size 16.9 µm were produced exhibiting meso-macro-pore structure with Sg=46m2/g and Sg=20m2/g respectively, similar to those reported in literature for applications such drug carriers e.t.c. Chitosan which was identified via NMR technique, exhibiting 91% deacetylation degree which means high water and gas barrier behavior, is also reported in this study. Finally, nitrogen/sulfur dopped carbon quantum dots were produced during this research, visually certified by UV luminescence experiments at 245 nm and 365 nm UV-light wavelength, exhibiting an identified via AFM technique mean size of 5.01 nm, and successfully tested for their advanced antioxidant capabilities via the DPPH assay and antimicrobial properties via MIC routine measurements with E. coli and L. monocytogenes. Concluding, the waste-shells from Crayfish and other crustaceous could be exploited for added value materials production yielding economic and environmental benefits.
Spacelike curves and evolution equations in de Sitter 3-space
Authors: Saad M. Khalifa , Abdel-Aziz H. S. 
Published: December 2023

Abstract
In this paper, we study the geometry of moving spacelike curves in the three-dimensional
de Sitter space. Then, the evolution equations of the pseudo-orthonormal frame and the curvatures
for these curves are derived. Moreover, some conditions for an inelastic curve flow are presented.
Finally, interesting illustrative examples of the obtained results are given and plotted.
Applying Markov Decision Processes to Evaluate Ransomware Data Theft Risks
Authors: Zhu Tingting , Li Xiang , Zhang Wenbo 
Published: December 2023

Abstract
Ransomware has rapidly evolved into sophisticated, stealthy threats built to extort payments through data encryption and extraction. This paper presents an innovative methodology for ransomware risk evaluation using the mathematical frameworks of Markov Decision Processes (MDP). By modeling ransomware scenarios as MDPs, overlaying risk equations, and applying our analysis, a quantitative assessment of dynamic risk levels and effectiveness of defensive strategies is enabled. The technique is demonstrated through comparative assessment of prominent ransomware groups, industry-specific impact analysis, and time projections of data theft risk trajectories. Despite limitations in model complexity and real-world validation, the methodology elucidates an interdisciplinary approach blending decision theory, control systems and applied mathematics to enrich cyber risk research.