bluuebunny/crossref_metadata_2025_split huggingface dataset:
Chitosan-based Nanomedicine in the Management of Age-related Macular Degeneration: A Review
Authors: Mukherjee Swarupananda , Karati Dipanjan , Singh Sudarshan , Prajapati Bhupendra G. 
Published: December 2023

Abstract:Age-related macular degeneration (AMD) is a leading cause of permanent blindness globally. Due to the various obstacles, highly invasive intravitreal (IVT) injections are the prima-ry method used to deliver medications to the tissues of the posterior eye. An utmost patient-friendly topical ocular delivery approach has been extensively researched in recent years. Muco-adhesive compositions extend precorneal residence time while reducing precorneal clearance. They increase the likelihood of adhesion to corneal and conjunctival surfaces and, as a result, al-low for enhanced delivery to the posterior eye segment. Due to its remarkable mucoadhesive characteristics, chitosan (CS) has undergone the most extensive research of any mucoadhesive polymer. Drug delivery to the front and back of the eye is still difficult. The pharmaceutical in-dustry has shown greater interest in drug delivery systems (DDSs) based on nanotechnology (NT) in recent years, particularly those made from natural polymers like chitosan, alginate, etc. Be-cause of their incredible adaptability, higher biological effects, and favourable physicochemical properties, CS-oriented nanomaterials (NMs) are explored by researchers as prospective nanocar-riers. CS are the right substrates to develop pharmaceutical products, such as hydrogels, nanopar-ticles (NP), microparticles, and nanofibers, whether used alone or in composite form. CS-based nanocarriers deliver medicine, such as peptides, growth factors, vaccines, and genetic materials in regulated and targeted form. This review highlights current developments and challenges in chi-tosan-mediated nano therapies associated with AMD.
Sensores de calidad de agua para el control de la contaminación fisicoquímica en los acuíferos de Latinoamérica: una revisión
Authors: Franco Edian F , Ramos Rommel , Ovando-Javier Argeny , Montero-Espaillat Emanuel , Bonilla Solhanlle , Veda Atharva 
Published: December 2023

El monitoreo de la calidad del agua es un aspecto crítico para garantizar agua segura y limpia para el consumo humano, los procesos industriales y la vida acuática. El empleo de sensores automáticos basados en el internet de las cosas y algoritmos de aprendizaje de máquina utilizados para el monitoreo de la calidad del agua se ha vuelto cada vez más popular, debido a su facilidad de uso, precisión y rentabilidad. En esta revisión, discutiremos algunos de los sensores comúnmente utilizados para la vigilancia de la calidad del agua, así como sus posibles usos para la gestión y supervisión de acuíferos en América Latina. En la primera parte se discute sobre la contaminación de las fuentes de agua en Latinoamérica y, especialmente, en República Dominicana, donde se brinda una revisión de los diferentes trabajos que evalúan la contaminación en afluentes de agua. Además, se explora como el uso cotidiano de estas fuentes de agua puede afectar a los seres humanos. En la última parte del trabajo se presentan las tecnologías de los sensores y sus diferentes implementaciones, así como los principales retos para su integración al monitoreo de la calidad de agua de las fuentes de agua. Esta revisión demostró que el uso de sensores remotos de calidad de agua, basados en tecnologías de IoT y algoritmos de inteligencia artificial son de gran importancia para el control de la contaminación fisicoquímica en los acuíferos de los países latinoamericanos. Estos sensores constituyen una herramienta clave para el manejo sostenible de los recursos hídricos.
Impactos da pandemia do covid-19 aos incidentes com múltiplas vítimas nas rodovias federais brasileiras
Authors: Rodrigues da Costa Fernanda , Marcelo Fernandes de Lima Raylson , Claudia Silva de Araújo Emylly , Hillary Silva Costa Raquel , Keven da Silva Fernandes Luan 
Published: December 2023

Os Incidentes com Múltiplas Vítimas (IMV) tem causas socioeconômicas e ambientais e gera grandes impactos na saúde pública, excedendo a morbimortalidade. Analisar os impactos da pandemia do COVID-19 às Incidente com Múltiplas Vítimas nas rodovias federais brasileiras. Trata-se de um estudo quantitativo descritivo, acerca dos impactos da COVID-19 frente aos IMV nas rodovias federais brasileiras, por meio de dados encontrados no site da Polícia Rodoviária Federal (PRF) no período de 2018 a 2020, no qual obteve-se amostra final de 17.727 incidentes. Os mesmos foram avaliados por meio de estatística descritiva e apresentados em formato boxplot, separados por regiões brasileiras. Nota-se que o estado de Rondônia apresentou a maior taxa no ano de 2018 e igualando as taxas no ano de 2019 com o estado de Santa Catarina, período sem pandemia. Ao analisar o período pandêmico, observa-se que o estado de Santa Catarina permanece com as maiores taxas no primeiro ano, entretanto, no segundo ano tem-se como destaque o estado do Mato Grosso do Sul. Evidencia-se que o estado do Amazonas se destaca em todos os anos analisados, seguido pelo o estado de São Paulo com as menores taxas. Embora as taxas de Incidentes com Múltiplas Vítimas nas rodovias federais brasileiras tenham apresentado declínio no período pandêmico de forma nacional, evidencia-se que não houve diminuição significativa nas estatísticas, entretanto, em alguns estados e regiões nota-se um aumento nas taxas no segundo ano de pandemia.
Importância do cirurgião-dentista no diagnóstico de manifestações orofaciais de violência sexual infantil – revisão de literatura
Authors: Araújo da Silva Taina Fabiana , Carvalho de Araújo Oliveira Maria Vitória , Andrade de Lacerda Juliana , Damião Costa Denis 
Published: December 2023

O Cirurgião-Dentista deve ser capaz de identificar manifestações orofaciais provenientes de violência sexual infantil, uma vez que a maioria das lesões acometem sua área de atuação, nas regiões de cabeço e pescoço. O presente trabalho objetiva, por meio de revisão da literatura, apontar a importância e conduta deste profissional frente a violência sexual contra crianças, aspectos legais relacionados, achados odontológicos sugestivos dessas agressões que variam desde marcas de mordidas com equimoses de sucção no pescoço até laceração dos freios labial e/ou lingual ou presença de petéquias palatinas, assim como, descrever a manifestações de Infecções Sexualmente Transmissíveis em menores violentados sexualmente, sendo as principais Sífilis, HPV, Gonorreia, Herpes, Candidíase e HIV/AIDS. As informações são oriundas da legislação vigente e literatura especializada nacional e internacional relativas ao tema, pesquisadas nas bases de dados SciELO, PubMed e LILACS. Visto que, em sua graduação, o Odontólogo recebe pouca ou nenhuma base referente às principais manifestações físicas orofaciais e psicológicas de violência sexual contra este público, a grande maioria não consegue diagnosticar corretamente e, consequentemente, não cumpre seu papel de notificar casos suspeitos, seja por insegurança, medo ou por desconhecer sua obrigação legal. É necessário que a temática seja abordada mais profundamente durante a graduação e pós-graduação para capacitar o profissional da odontologia a como conduzir esses casos e para que também não existam omissões.
PALAVRAS CHAVE: Abuso Sexual na Infância. Notificação de Abuso. Odontologia Legal.
Ice Floe Tracker: An Open-Source Tool Enabling Novel Observations of Sea Ice Motion from Visual Remote Sensing Imagery
Authors: Watkins Daniel Mark , Buckley Ellen , Kim Minki , Paniagua Carlos , Divoll Timothy , Restrepo Maria I , Wilhelmus Monica M 
Published: December 2023

Ice Floe Tracker is an open-source tool designed to retrieve
floe-scale sea ice motion in the Arctic marginal ice zone during spring
and summer. Ice Floe Tracker enables observation of the floe size
distribution, ice floe rotation rates, small-scale variation in floe
velocity, and individual floe trajectories. Sea ice motion occurs on a
wide range of scales, from the interaction of individual pieces of ice
at sub-meter scales, the formation of linear kinematic features, and ice
transport via basin-wide gyres. Most existing methods for tracking ice
motion from remote sensing imagery rely on cross-correlation and are
optimized for the winter season in the central Arctic.
Cross-correlation-derived motion vectors estimate area-averaged motion
and thus are well-suited for close-packed central Arctic ice; however,
such estimates have high uncertainties in the dynamic, strongly
deforming sea ice cover of the marginal ice zone. Our tool aims to fill
this gap by using shape detection and feature tracking to observe
floe-scale ice motion.

The Ice Floe Tracker algorithm consists of a series of
customizable modules. The code is structured as a modular package
written in open-source languages. It includes parallel processing, unit
testing, a command line interface, and thorough documentation (available
on Github). Routines are provided to download imagery from the NASA
Moderate Resolution Imaging Spectroradiometer. The satellite imagery is
processed to enhance the contrast between liquid water and sea ice,
sharpen floe boundaries, and remove atmospheric noise. The image is then
segmented, and geometric features of ice floes are extracted. Finally,
ice floe geometry and locations are compared to those in subsequent
images and linked to form trajectories. By making this tool
open-source, we aim to encourage cross-disciplinary collaboration.
Recent results from collaborations between observational oceanography
and discrete-element sea ice model development will be highlighted.
Novel, speculative highly-scaled carbon removal study on a reduced complexity model, showing a return to preindustrial temperatures by 2100 and updates to achieving net-zero for Anthropocene reversal. Poster B43K2705 presented at AGU23, 11-14 Dec. 2023
Authors: Fiume Shannon A. 
Published: December 2023

Speculations extend the opportunity space of possible future climates by
increasing the potential to provide plausible estimated qualities and
quantities to further scientific research and aid engineering solutions.
This novel work outlines the first steps to achieving an Anthropocene
reversal that completes in Zoomers’ lifetimes — by 2100. The novel
experimental high-scale carbon removal pathway, which was studied in
MAGICC 6.8, required CDR to counterbalance all accumulated anthropogenic
emissions since 1750 to return to preindustrial temperature (0.07ºC over
the 1720-1800 and 0.14ºC over the 1850-1900) means by 2100 and complete
GHG phaseouts by 2077, excluding Ammonia. The experimental pathway set
extreme front loading of emissions reductions to reach net zero, and
avoid tipping points, then achieve scaled removal to reach 300 ppm of
CO concentration by roughly mid-century. This work’s
findings recommend exploring carbon removal of cumulative anthropogenic
emissions totaling 600 GtC to 775 GtC on a recent model ensemble with
1.55 to 1.7 times preindustrial CO concentration driven
by forcings from emissions and calibrate to reproduce present-day
temperatures to provide more detailed projections of temperature,
holding below 1.5ºC, regional temperatures, below ground
CO mineralization, sea-level rise, ENSO, AMOC, and
jet-stream turnover, evolve.
Continued fossil-fuel use is unable to yield complete emissions
phaseouts or deep removals necessary to match a preindustrial climate.
The findings support the utmost urgency to attain a maximally scaled
sustainable zero-carbon intensity green growth development. And
reinforce the increased global commitment to achieve net zero sooner and
to avoid setting off more climate tipping points. The possibility of
reaching a preindustrial climate should help inform the debate of
maximally scaled sustainable green growth development for the fastest
path to net zero, phase out of anthropogenic emissions sources, and
scaled carbon removals with zero-carbon intensity to develop a more
equal future world.
The Effect of Data Security Procedures and Big Data Analytics on Engineering Performance: A Case Study of Lagos (Iganmu) Industrial Layout
Authors: Falosole Adetayo , Adegboye Oluwasegun Solomon , Ekuewa Oluwaseun Isaiah , Oyegoke Muideen Ayomipo , Frederick Kwadwo Boakye 
Published: December 2023

The purpose of this research is to comprehend how big data analytics affect engineering performance. The industrial part especially the engineering practice is among the most significant and delicate in the world. Gathering and manufacturing have a huge social impact on the economies of the nations and, consequently, on the lives of individuals all over the world. The potential for big data to completely alter engineering practice and enhance ongoing engineering projects. Many organizations appear to be aware of the advantages big data can bring to their performance in engineering practice, particularly its significant possible worth, but they encounter a number of challenges when implementing it, primarily because they are having trouble figuring out how to use the derived insights for their development.
The development of new strategies and services is a crucial engineering activity, and it has been demonstrated to significantly affect an organization’s viability. If these insights are monetized, Organizations aiming for an improved engineering practice can build brand-new, customer-centered, and data-driven projects or both goods and services, providing a long-lasting competitive advantage and new revenue streams. According to empirical research, companies that have engineering practice incorporated with a data-driven approach that can show how big data contributes to improved performance, while those that have not yet instilled the entire organization struggle with an absence of comprehension on how to use big data technology to create potential value and accomplish their organizational goals.
Due to the enormous strategic potential of big data, this article tries to conceptualize and investigate its effects on corporate performance. It also explores the impacts of big data on engineering performance because of its high strategic potential. Finally, it explores whether and how the creation of new engineering services and projects makes use of big data and related technologies. An in-depth SWOT, binary Logistic Regression analysis, and the use of grounded theory combine previous big data studies with several enterprises in Lagos, Nigeria’s Iganmu industrial layout area. The caliber of data gathered, data availability, legal considerations of data confidentiality and safekeeping, and highly qualified individuals working with big data are additional critical factors that influence the use of a data-driven approach. Therefore, in order for companies to achieve effectiveness and efficiency, they need to reflect on and make strategic decisions utilizing a comprehensive perspective on big data.
INTERNALIZATION OF RELIGIOUS VALUES THROUGH SOCIAL INTERACTION OF SMKN 1 KLATEN STUDENTS
Authors: Oktafiana Alfina Tri , Inayati Nurul Latifatul 
Published: December 2023

This research was conducted in order to find out how teachers implement Islamic values in students at SMK N 1 Klaten. This research aims to find out what methods are used to implement values in school activities at SMK N 1 Klaten. This research study uses a qualitative descriptive method. This research is included in the classification of field research carried out at SMK N 1 Klaten. The data obtained from this research is through observations, interviews, and documentation from school principals, PAI teachers, and students of SMK N 1 Klaten. The results of this research show that there are several methods for implementing Islamic values carried out at SMK N 1 Klaten, including the habit of reading the Al-Qur'an before learning, dhuha prayers in congregation, and students' religious activity sheets. In the implementation of school activities there are also supporting and inhibiting factors. Supporting factors include support from parents/guardians and from the school. Meanwhile, the inhibiting factors come from the students' different backgrounds. Based on the results of research regarding the implementation of Islamic religious values at SMK N 1 Klaten using the habituation method in school activities, including reading the Al-Qur'an before the first lesson begins, praying Dhuha in congregation, and religious activity sheets for students, The implementation of several of these habits is carried out according to each habit and is carried out at any time in everyday life. In implementing this habituation, supporting and inhibiting factors arise. Supporting factors include support from parents and guardians as well as from the school, which always controls students to always implement Islamic religious values. Meanwhile, the inhibiting factors include students' different backgrounds in reading the Al-Qur'an, but teachers at SMK N 1 Klaten have a solution to this by directing students to take part in the BTA extracurricular.
TRANSFORMASI PENDIDIKAN ISLAM PADA PEMBELAJARAN DAN NILAI KEISLAMAN DI ERA REVOLUSI INDUSTRI 4.0
Authors: Nugraha Cecep , Nawawi Aif Umar , Asianto Muhamad Fajar , Ramlan Ridwan Septiyadi , Jenuri Jenuri 
Published: December 2023

Perubahan pendidikan Islam di era Revolusi Industri 4.0 telah mengubah tatanan sosial, ekonomi, dan pendidikan global, nilai dan identitas keislaman dengan penggunaan teknologi digital, AI, dan konektivitas tinggi. Penelitian ini bertujuan untuk menganalisis dan memahami pendidikan Islam yang mengalami transformasi di era Revolusi Industri 4.0 dan mengevaluasi dampak transformasi tersebut pada pembelajaran dan nilai keislaman dalam pendidikan Islam. Metode penelitian yang digunakan dalam penelitian ini yaitu metode penelitian kualitatif dengan metode pendekatan studi literatur atau penelitian literatur. Upaya untuk meningkatkan sistem pendidikan Islam secara menyeluruh yang dapat dilakukan dalam pendidikan Islam adalah perbaikan aturan yang berlaku, orientasi pendidikan pada kebutuhan masa depan, peninjauan dan perbaikan kurikulum, peningkatan kualitas manajemen sekolah, peningkatan kapasitas dan kemampuan pimpinan sekolah, peningkatan kemampuan guru, keterlibatan masyarakat dalam pembangunan sekolah, digitalisasi layanan akademik, administrasi, dan pembelajaran. Kesimpulan dari penelitian ini yaitu Era Revolusi Industri 4.0 telah mengubah pendidikan Islam dengan teknologi yang memberikan peluang dan tantangan. Kombinasi pendekatan tradisional dan teknologi sebagai alat pendukung adalah solusi terbaik. Kolaborasi antara masyarakat, pemerintah, dan lembaga pendidikan diperlukan untuk menciptakan pendidikan Islam inklusif dan relevan.
IMPLEMENTASI PROJEK PENGUATAN PROFIL PELAJAR PANCASILA MENURUT PERSPEKTIF AL-QUR’AN DAN HADIST
Authors: Iskandar Iskandar , Patimah Siti , Subandi Subandi , Makbulloh Deden 
Published: December 2023

Sebagai upaya memenuhi tantangan Abad 21 perlu adanya transformasi pada dunia Pendidikan. Pendidikan yang diharapkan mampu membentuk karakteristik bangsa yang intelek, maju diberbagai bidang, serta perilaku, etika , moral yang positif. Arikel ini bertujuan untuk memahami proyek penguatan profil pelajar Pancasila sebagai penguatan Pendidikan karakter pada peserta didik dari perspektif Al-qur’an dan Hadist. Penulisan ini menggunakan pendekatan kualitatif untuk mengumpukan data dan sumber data yang relevan untuk penelitian ini. Dalam perspektif Al-qur’an bahwa penerapan profil pelajar Pancasila tercermin dalam 6 dimensi yaitu beriman dan bertaqwa kepada Tuhan YME dalam QS.Ali-imran:102, berkebhinekaan global sesuai dengan QS.Al-hujarat:13 dan Ar-rum:22, gotong royong sebagaiaman dalam QS.al-maidah:2 dan al-imran:104, Mandiri dalam QS.ar-rad:11, bernalar kritis dalam QS.ali-imran:190-191 dan kreatif dalam QS.al-baqarah:44. Semua hal yang berkaitan dengan karakter atau sikap dalam kehidupan manusia, sudah termuat dalam Al-Qur’an tinggal bagaimana kita memahami dan menjalankan dalam kehidupan.
KOMPETENSI KEPRIBADIAN GURU DALAM PERSPEKTIF BUYA HAMKA DAN UNDANG-UNDANG REPUBLIK INDONESIA TENTANG GURU DAN DOSEN NOMOR 14 TAHUN 2005
Authors: Rismawan Arbi , Iswati Iswati , Kuliyatun Kuliyatun 
Published: December 2023

Setiap guru mempunyai kepribadian dan latar belakang yang berbeda. Kepribadian yang sebenarnya adalah suatu yang abstrak, hanya dapat dilihat lewat penampilan, ucapan, tindakan, dan cara menjawab persoalan. Beberapa kasus yang telah terjadi dalam dunia pendidikan yakni, kurangnya kompetensi guru dalam beretika. Adapun tujuan penelitian ini adalah untuk memotret kompetensi kepribadian guru dalam perspektif Buya Hamka dari buku pribadi hebat dan untuk memotret kompetensi kepribadian guru menurut UU RI No.14 Tahun 2005 tentang Guru dan Dosen. Jenis penelitian yang digunakan adalah penelitian kajian dengan pendekatan kualitatif dengan library research. Pada penelitian ini teknik pengumpulan data yang digunakan yaitu, teks dan wacana, dokumentasi. Penelitian ini menunjukan bahwa kompetensi kepribadian guru perspektif Buya Hamka yaitu seorang guru harus percaya kepada diri sendiri, bijak dalam berbicara, kesehatan tubuh, tahu diri, berpandangan baik, bijaksana, berani, menimbang rasa, cerdik, dan daya tarik. Kompetensi kepribadian guru menurut UU RI No.14 Tahun 2005 tentang Guru dan Dosen yaitu kemampuan kepribadian yang disiplin, jujur dan adil, mantap, stabil, dewasa, arif dan penyabar, berwibawa, menjadi teladan bagi peserta didik, memiliki rasa percaya diri dan berakhlak mulia. Dengan demikian, ada kesesuaian antara pendapat Buya Hamka dengan UU RI No.14 Tahun 2005. Sehingga kompetensi kepribadian menurut Buya Hamka bisa diaplikasikan oleh guru pada masa sekarang.
Novels 1914-1916 to the General Civil Code of the Austrian Empire 1811
Authors: Savuliak R.V. 
Published: December 2023

The article is devoted to clarifying the reasons and prerequisites for the adoption of the Novels of 1914-1916 to the Austrian General Civil Code of 1811, a general characterization of their content and substantiation of their historical and legal significance.
The author analyzed the state of problem processing; first of all, the author used the works of two professors of Lviv University of 20th century - the outstanding Polish civilian Ernest Till, who published the German text and the Polish translation of the Novel with his own explanations, as well as the prominent Ukrainian jurist Stanislav Dnistrіanskyі, who in 1919 translated the Code of 1811 and three Novels to it into Ukrainian. At the same time, the main attention in the article is given to the figure of the Austrian lawyer and statesman, professor of the University of Vienna, Joseph Unger, who presented the program of novelization of the Code of 1811 in his article of 1904 and later acted as its main developer at the head of the Special Commission.
The author revealed the decisive influence of J. Unger on the spread of the historical school of law in the legal science of the Austrian monarchy, including its fundamental provisions regarding the reception of Roman law, the tradition of German pandectism; and, instead, critics of the theory of natural law; as well as on the introduction by scientists of a comparative legal approach in Austrian civil studies, thanks to which the reform of the General Civil Code of the Austrian Empire in 1811 was initiated. The author considered the 10-year codification process of changing the Code, which resulted in its novelization in 1914-1916.
Therefore, the article elaborates the main content of the three Novels to the Code: the First Novel of October 12, 1914, the Second Novel of July 22, 1915, and the Third Novel of March 19, 1916, which made certain changes to personal, family, property, inheritance and obligation law. At the same time, the author stated that the revision of the General Civil Code of the Austrian Empire in 1811 did not fundamentally change its structure, nor the main principles and provisions, but was only aimed at adapting the Code to the contemporary conditions and needs.