bluuebunny/crossref_metadata_2025_split huggingface dataset:
Twenty-year experience following aortic valve replacement in patients younger than 60 years of age
Authors: Imamura Yuki , Kowatari Ryosuke , Koizumi Junichi , Tabayashi Azuma , Saitoh Daiki , Kin Hajime 
Published: February 2024

Abstract

Objective: Reports on long-term outcomes of surgical aortic valve replacement (AVR) for patients aged <60 years are scarce in Japan. Hence, we aimed to evaluate these outcomes in patients aged <60 years.
Methods: Between March 2000 and December 2020, 1477 patients underwent aortic valve replacement. In total, 170 patients aged <60 years who underwent aortic valve replacement were recruited. Patients aged <18 years were excluded. Patient data collected from the operative records and follow-up assessments were reviewed.
Results: The mean age was 49±9 years, and 64.1% of patients were male. One-hundred-and-fifty-two patients (89.4%) underwent aortic valve replacement with a mechanical valve and 18 (10.6%) with a bioprosthetic valve. The mean follow-up period was 8.1±5.5 years. No operative mortality occurred, and in-hospital mortality occurred in one patient (0.6%). Ten late deaths occurred, with seven cardiac-related deaths. The overall survival rate was 95.4±1.7%, 93.9±2.3%, 90.6±3.9%, and 73.2±11.8% at 5, 10, 15, and 20 years, respectively. Freedom from major bleeding was 96.4±1.6% at 5, 10, and 15 years, and 89.0±7.3% at 20 years. Freedom from thromboembolic events was 98.7±1.3%, 97.3±1.9%, 90.5±4.5%, and 79.0±11.3% at 5, 10, 15, and 20 years, respectively. Freedom from valve-related reoperation was 99.4±0.6% at 5 years, 97.8±1.7% at 10 and 15 years, and 63.9±14.5% at 20 years.
Conclusions: Patients aged <60 years undergoing aortic valve replacement with a high mechanical valve implantation rate had favorable long-term outcomes.
Genetic analysis on basmati rice varieties in Indian market using SSR markers
Authors: Kuncham Ramprasad , Mohanty Mausumee , Goriparthi Koteswara Rao , Thekkeetil Prasanth , Vannereddy Muniraju , Sivaprakasam Thiyagarajan 
Published: February 2024

Abstract
In the world of rice, among the thousands of varieties that are available, inarguably Basmati rice occupies the prime position due to its accoladed traits such as grain morphology, quality, fragrance, taste, fluffy texture, and tenderness of cooked rice. Due to these unique traits, Basmati rice that is exported from India and Pakistan earns triplex price compared to domestic non-basmati rice varieties. Among the Basmati rice varieties, the Traditional Basmati rice varieties which are rich in nutrition values and aroma are considered as the premium class and hence most of these rice varieties are being exported to other countries. In the present study, three hundred and fifty (350) Basmati rice varieties were collected from various super markets and retail outlets across India which were evaluated for allelic behavior using 10 SSR markers. According to UK CoP, only 75 sample qualified out of 350 samples. A total of 77.12% of the rice were Basmati varieties including varieties like Pusa Basmati 52%, followed by 28% of Pusa Basmati 1121. Surprisingly, we could not detect any Traditional Basmati rice portions either partially or completely. Very limited number of brands have 100% Basmati rice, without any adulteration in them. Our findings demonstrate the absence of Traditional Basmati rice in the Indian market despite of being the largest producer of the same.
Wear in Progress: How Third Body Flow Controls Surface Damage
Authors: Bouillanne Olivier , Mollon Guilhem , Saulot Aurélien , Descartes Sylvie , Serres Nathalie , Chassaing Guillaume , Demmou Karim 
Published: February 2024

Abstract
Mechanical contacts in dry conditions are often characterized by an interfacial layer called “third body”, which generally originates from the degradations of the surfaces, but which can exhibit strongly different material properties. This layer is a direct consequence of past wear, but also exerts a control on the rate at which surfaces in contact will keep getting worn. A comprehensive understanding of mechanical contacts therefore relies on a theory describing the interplay between this sheared layer and the moving surfaces which confine it. In this paper, we make a step towards such a theory by quantitatively investigating the link between the flow regime of the third body and the mechanical loading it applies to the surfaces. For that purpose, a previously developed local model of solid flow based on the Multibody Meshfree Approach is employed, in order to simulate characteristic flow regimes identified in experiments. Typical stress concentration patterns endured by the surfaces are then described and quantified, and a simple damage model is used to demonstrate how such a model could lead to wear prediction. We demonstrate that agglomerated flow regimes are prone to enhance large and deep damaging of surfaces, while granular third body flows have a more limited and shallow damaging effect.
Prevalence of Anxiety, Depression, and Post-Traumatic Stress Disorder Among Omani Children and Adolescents Diagnosed with Cancer: A prospective cross-sectional study
Authors: Al-Saadi Laila , Chan Moon Fai , Sabahi Amal Al , Kendi Jalila Al , Mashaikhi Nawal Al , Sumri Hana Al , Al-Fahdi Amal , Al-Azri Mohammed 
Published: February 2024

Abstract

Background
Children and adolescents diagnosed with cancer often experience psychological distress, encompassing anxiety, depression, and post-traumatic stress disorder (PTSD). This study aimed to evaluate the prevalence of these conditions among Omani children and adolescents diagnosed with cancer, alongside identifying contributing factors.
Methods
A prospective cross-sectional study was conducted from October 2021 to June 2023 among a cohort of Omani children and adolescents (6–18 years old) diagnosed with cancer at three primary cancer referral centres in Oman. Validated Arabic-language versions of the Screen for Child Anxiety Related Disorders, the Center for Epidemiologic Studies Depression Scale for Children, and the Impact of Event Scale-Revised instruments were used to assess symptoms of anxiety, depression, and PTSD, respectively. An initial assessment (T1) was undertaken within the first 3 months of diagnosis, followed by a second assessment (T2) 3–6 months later.
Results
Of 113 eligible participants, 101 agreed to participate in the study (response rate: 95.6%), with 92 (91.0%) completing both assessments and included in the final analysis. Prevalence rates of anxiety, depression, and PTSD decreased from 43.5%, 56.5%, and 32.6%, respectively, at T1, to 38.0%, 35.9%, and 23.9% at T2. All average scores were below diagnostic cut-off points, except for the depression score at T1. Anxiety and depression scores decreased significantly (p = 0.043 and 0.001, respectively) between T1 and T2, as did the overall prevalence of depression (p = 0.004). At T1, linear regression analysis showed significant correlations between anxiety scores and the child’s age and PTSD score (p < 0.05); these variables were also correlated with depression scores (p ≤ 0.001). At T2, significant correlations were observed between anxiety scores and the child’s age and PTSD scores (p < 0.001). At both T1 and T2, anxiety, depression, and PTSD scores remained significantly correlated (p < 0.001).
Conclusions
Omani children and adolescents recently diagnosed with cancer exhibit a high prevalence of anxiety, depression, and PTSD over time. Age-appropriate communication, ongoing support, and mental health services are recommended to help this patient group cope with their diagnosis and manage their emotional wellbeing. There is a need for future research to determine the effectiveness of specific psychological interventions in reducing the frequency of these disorders.
Machine Learning-Based Prediction of Post-Induction Hypotension: Identifying Risk Factors and Enhancing Anesthesia Management
Authors: Ming Chen , Zhang Dingyu 
Published: February 2024

Abstract

Background: Post-induction hypotension (PIH) increases surgical complications including myocardial injury, acute kidney injury, delirium, stroke, prolonged hospitalization, and endangerment of the patient's life. Machine learning is an effective tool to analyze large amounts of data and identify perioperative complication factors. This study aims to identify risk factors for PIH and develop predictive models to support anesthesia management.
Methods: A dataset of 5406 patients was analyzed using machine learning methods. Logistic regression, random forest, XGBoost, and neural network models were compared. Model performance was evaluated using the area under the receiver operating characteristic curve (AUROC), calibration curves, and decision curve analysis (DCA).
Results: The logistic regression model achieved the highest AUROC of 0.74 (95% CI, 0.71 - 0.77), indicating good discrimination. Calibration curves demonstrated satisfactory calibration for the logistic regression and random forest models. DCA revealed that the logistic regression model had the highest clinical benefit. The logistic regression model showed the best performance in predicting PIH and was selected as the final predictive model. Baseline blood pressure, age, sex, type of surgery, platelet count, and certain anesthesia-inducing drugs were identified as important features.
Conclusions: This study provides a valuable tool for personalized preoperative risk assessment and customized anesthesia management, allowing for early intervention and improved patient outcomes. Integration of machine learning models into electronic medical record systems can facilitate real-time risk assessment and prediction.
A Green, Facile, and Practical Preparation of Capsaicin Derivatives with Thiourea Structure
Authors: Chen Lina , Gao Zhenhua , Zhang Ye , Dai Xiandong , Meng Fanhua , Guo Yongbiao 
Published: February 2024

Abstract

A green, facile, and practical synthetic method of capsaicin derivatives with thiourea structure is developed by using an automated synthetic system, leading to a series of capsaicin derivatives with various electronic properties and functionalities in good to excellent yields.
Effects of Partially/Masked Face on the Personality Identifying: Self-Multimodal Fusion Consideration
Authors: Esmail Anter , El-Bendary Mohsen A. M. , Aboshosha Ashraf , El-Tokhy M. , Haggag Ayman 
Published: February 2024

Abstract
Due to the essential using of mask face in various fields and critical situations, there is urgent need to develop techniques for identifying personality to be more effective in presence the mask face. Also, Muslim women who wear Higab, they suffer from the traditional identifying processes. Facial recognition techniques have become ineffective with face mask. In this research, the technique of identifying the personality through the face with the mask was proposed by making a fusion between both the original face and part of the face, using Score fusion and features fusion. The research presented an extensive study of the effect of the mask on the difficulty of recognizing the face and changing the facial features. The research used more than one tool to extract the features of a face image with a mask, and a group of classification tools to identify the personality more accurately. More than one extraction tool has been combined to increase the classification accuracy. The different feature extracting of voice and masked face images are used with employing the various classifiers such as the Support Vector Machine (SVM), K-Nearest Neighbours (KNN), Gaussian Mixture Model (GMM) and Artificial Neural Network (ANN) tools. The simulation experiments results prove the superiority of score based fusion.
Changes in bone microstructural characteristics and the position of condyle head after orthognathic surgery with or without condylar resorption
Authors: Miyagawa Kazuaki , Arikawa Chihiro , Hayashi Koichi , Seki Soju , Yokota Yusuke , Harada Kazuma , Tanaka Susumu , Isomura Emiko Tanaka 
Published: February 2024

Abstract
Condylar resorption occurs in some cases after orthognathic surgery, and the risk factors associated with postoperative condylar head resorption have been extensively described. Nevertheless, even in cases with a combination of risk factors, postoperative condylar resorption may not appear. This study analyzed the microstructure and three-dimensional positional change of the condylar bone via imaging in patients who have undergone bimaxillary orthognathic surgery to determine whether the microstructure differs between patients with and without postoperative condylar resorption. Among asymptomatic patients who underwent bimaxillary surgery between April 2021 and March 2022 at our department, the bone microstructure of 17 patients was analyzed, limited to “female,” “skeletal Class II,” and “high-angle cases,” which are known risk factors for mandibular head resorption. Multidetector computed tomography was performed on these patients before and 6 months after surgery, and the bone microstructure of the condylar head was compared with the three-dimensional positional changes of the condylar bone and the proximal bony fragments according to whether the condylar head was resorbed after surgery using the bone morphology software TRI/3D-BON. Patients with condylar bone abnormalities before surgery and those with high trabecular bone density can develop postoperative resorption if the condyle is misaligned during surgery.
Transgenic Tobacco Plants Overexpressing a wheat Salt Stress Root Protein (TaSSRP) Exhibit Enhanced Tolerance to Heat Stress
Authors: Azameti Mawuli K. , N Tanuja , Kumar Satish , Rathinam Maniraj , Imoro Abdul-Wahab M. , Singh P. K , Gaikwad Kishor , Sreevat Rohini , Dalal Monika , Arora Ajay , Rai Vandna , Padaria Jasdeep C. 
Published: February 2024

Abstract

Heat stress is a detrimental abiotic stress that limits the development of many plant species and is linked to a variety of cellular and physiological problems. In this study, gene TaSSRP from the heat stress-tolerant wheat genotype Raj 3765 was functionally validated in transgenic tobacco for heat stress tolerance. The Relative Water Content (RWC), total chlorophyll content, and Membrane Stability Index (MSI) of the seven distinct transgenic lines (T0 − 2, T0 − 3, T0 − 6, T0 − 8, T0 − 9, T0 − 11, and T0 − 13), increased in response to heat stress. Despite the fact that the same tendency was detected in wild-type (WT) plants, changes in physio-biochemical parameters were greater in transgenic lines than in WT plants. The expression analysis revealed that the transgene TaSSRP expressed from 1.00 to 1.809 folds in different lines in the transgenic tobacco plants. The gene TaSSRP offered resistance to heat stress in Nicotiana tabacum, according to the results of the study. These findings could help to improve our knowledge and understanding of the mechanism underlying thermotolerance in wheat, and the novel identified gene TaSSRP could be used in generating wheat varieties with enhanced tolerance to heat stress.
Frontal Epidural Schwannoma: case report and review of the literature
Authors: Li Jiaqi , Shi Xinkang , Zhou Manxin , Tang Tao , Ye Feng , Liu Yi 
Published: February 2024

Abstract
Background：Schwannomas that occur in the brain and spinal cord parenchyma are very rare. Here, we have identified a rare case of epidural schwannoma and reviewed the reported cases in the literature.
Case presentation：A 21-year-old woman has a slowly growing, 3-centimeter sized mass in the frontal area of her head. Radiography shows a space occupying lesion in the left frontal epidural space, and the tumor has penetrated the skull. We performed a complete surgical excision of the tumor, during which the tumor was seen to pass through the skull and tightly adhere to the outer layer of the dura mater. Postoperative histopathology confirmed a schwannoma. The patient was discharged without any neurological defects.
Conclusion: Although it is difficult to distinguish the nature of intracranial epidural space occupying lesions pre-operation, it broadens the scope of epidural diseases. It is important to include epidural schwannoma in differential diagnosis when the patient is young and/or the tumor lacks the dural tail sign.
A GIS Based Approach to Identify Potential Aquaculture Site in Cachar District of Assam, India
Authors: B Mohammed Imthathullah , Kumar Avinash 
Published: January 2024

Abstract
This study briefly discusses about the present condition of aquaculture in the cachar district of Assam province in India and aids in the development of aquaculture production in the district by identifying the best suitable location for the pond culture technique. The main indent of this study is to highlight the role of Geographical Information System (GIS) and Remote Sensing (RS) in identifying the Suitable areas for aquaculture in cachar district of Assam. Satellite images obtained from LANDSAT-8, Sentinel-2B, and Space Shuttle Radar Topographic Mission (SRTM) were used in this Study. Decision Support System (DSS) methods were utilized for calculation of suitable sites. DSS was used to delineate areas. It was encountered by comparing the DSS models with the spatio-temporal images of Google Earth that the anticipated area exhibits the presence of available ponds, confirming the demarcation is reasonable. It was predicted that about 5.16% of the total land area of 3786 km2 is most suitable for aquaculture by the DSS methods. It has also predicted that about 15.2% of the of the area is moderately suitable for Aquaculture. It is also found that the hilly regions of north and eastern region of the district is not suitable for aquaculture. The study demonstrated the significance of integrating remote sensing, GIS, and qualitative data selecting appropriate sites for the development of aquaculture ponds and the significance of being an effective instrument for professionals to establish strategic plans for aquaculture development.
A novel ACE inhibitory peptide from Pelodiscus sinensis Wiegmann meat
Authors: Liu Huayu , Sun Xueqin , Zhang Xinrui , Zhang Miao , Wang Xianyou , Liao Pengying , Jun Chen 
Published: January 2024

Abstract
Pelodiscus sinensis meat is a nutritional food and tonic with angiotensin-converting enzyme (ACE) inhibitory activities. To identify the bioactive substances responsible, several bioinformatics methods were integrated to enable a virtual screening for bioactive peptides in proteins identified within a water-soluble protein fraction of Pelodiscus sinensis meat by Shotgun proteomics. The peptides were generated from the identified proteins by in silico proteolysis using six proteases. A comparison of the numbers of proteins suitable for digestion with each enzyme and the iBAQ (intensity-based absolute quantification) values for these proteins revealed that bromelain and papain were the most suitable proteases for this sample. Next, the water solubility, toxicity, and ADMET (absorption/ distribution/ metabolism/ excretion/ toxicity) properties of these peptides were evaluated in silico. Finally, a novel ACE inhibitory peptide IEWEF with an IC50 value of 42.34 µM was identified. The activity of the synthesized peptide was verified in vitro, and it was shown to be a non-competitive ACE inhibitor. Molecular docking revealed that IEWEF could tightly bind to ACE, C-ACE, and N-ACE with energies of-8.9,-9.4, and-8.7 kJ·mol-1 , respectively. These results provide evidence that bioactive peptides in the water-soluble protein fraction account for (at least) some of the ACE inhibitory activities observed in Pelodiscus sinensis meat. Furthermore, our research provides a workflow for the efficient identification of novel ACE inhibitory peptides from complex protein mixtures.
MRI and pathology comparisons in Rasmussen’s Encephalitis: A multi-institutional examination of hemispherotomy outcomes relative to imaging and histological severity
Authors: Doherty Alexander , Knudson Kathleen , Fuller Christine , Leach James , Wang Anthony , Marupudi Neena , Han Rowland , Tomko Stuart , Ojemann Jeff , Smyth Matt , Mangano Francesco , Skoch Jesse 
Published: February 2024

Abstract
Purpose
Rasmussen encephalitis (RE) is a very rare chronic neurological disorder of unilateral inflammation of the cerebral cortex. Hemispherotomy provides the best chance at achieving seizure freedom in RE patients, but with significant risks and variable long-term outcomes. The goal of this study is to utilize our multicenter pediatric cohort to characterize if differences in pathology and/or imaging characterization of RE may provide a window into postoperative seizure outcomes, which in turn could guide decision making for parents and healthcare providers.
Methods
This multi-institutional retrospective review of medical record, imaging, and pathology samples was approved by each individual institution’s review board. Data was collected from all known pediatric cases of periinsular functional hemispherotomy from the earliest available electronic medical records. Mean follow up time was 4.9 years. Clinical outcomes were measured by last follow up visit using both Engel and ILAE scoring systems. Relationships between categorical and continuous variables were analyzed with Pearson correlation values.
Results
27 patients met study criteria. No statistically significant correlations existed between patient imaging and pathology data. Pathology stage, MRI brain imaging stages, and a combined assessment of pathology and imaging stages showed no statistically significant correlation to post-operative seizure freedom rates. Hemispherectomy Outcome Prediction Scale scoring demonstrated seizure freedom in only 71% of patients receiving a score of 1 and 36% of patients receiving a score of 2 which were substantially lower than predicted.
Conclusions
Our analysis did not find evidence for either independent or combined analysis of imaging and pathology staging being predictive for post peri-insular hemispherotomy seizure outcomes, prompting the need for other biomarkers to be explored. Our data stands in contrast to the recently proposed Hemispherectomy Outcome Prediction Scale and does not externally validate this metric for an RE cohort.
Laser irradiation and pomegranate peel extract as novel trends to preserve the strawberry quality characteristics
Authors: Elsayed Nesren , Elkashef Hany , Ahmed Abd El-Rahman , Hassan Helmy , Ali Shaimaa R. 
Published: February 2024

Abstract
The present study aimed to explore the influence of laser irradiation and coating with chitosan and pomegranate peel extract on the physico-chemical, weight loss, firmness, functional, microbiological, color, and sensory characteristics of strawberry fruits during fifteen days of cold storage. Four treatments of strawberry were treated with laser irradiation for 6 min. The second, third, or fourth group was coated with chitosan, pomegranate peel extract (PPE), or mixture of chitosan and PPE at ratio 1:1. Compared to untreated strawberries, the exposure to laser radiation decreased the weight loss of strawberries by 43.44%. Also, the laser irradiation reduced the negative effect of storage on the total phenolic content, anthocyanin, ascorbic acid, and antioxidant ability of strawberry. The exposure of strawberry to laser reduced the counts of fungi and psychrotrophic bacteria and exhibited the positive effect on the color and sensory attributes. The coating with PPE and chitosan enhanced the positive effect of laser irradiation on the functional and quality properties of strawberry during cold storage. Hence, it can be concluded that laser irradiation and coating with PPE may be applied as novel techniques for the preservation of strawberry properties during storage period.