bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between surface topography and contact in the elbow joint: Development of a two-dimensional geometrical model in the coronal plane
Authors: Waide D V , Lawlor G J , McCormack B A O , Carr A J 
Published: October 2002

One of the first stages in developing an accurate biomechanical representation of the elbow joint is to model realistically the geometry of the joint. In particular, given the complex anatomy of the articular surfaces, the relationship between surface topography and joint contact must be fully understood in order to model the contact conditions. As the joint articulates, the location and size of the contacts between the mating surfaces change, altering the distribution and magnitude of load transmission. In this paper, a geometric model of the anatomical elbow joint in the coronal plane is described. The contours of the articulating surfaces are represented algebraically by a series of connecting lines and circular arcs. It is shown that the location and size of the contact between the surfaces change significantly due to small changes in the topography of one or more of the mating surfaces. The surface topography-joint contact relationship is modelled for a number of different clinical conditions for the joint. The model is relevant to clinical studies of joint degeneration and to the design of prosthetic components for the elbow joint.
Influence of gelatin and bovine serum lubricants on ultra-high molecular weight polyethylene wear debris generated in in vitro simulations
Authors: Bell J , Besong A A , Tipper J L , Ingham E , Wroblewski B M , Stone M H , Fisher J 
Published: October 2002

Ultra-high molecular weight polyethylene (UHMWPE) wear debris induced osteolysis has a major role in the late aseptic loosening and ultimate failure of total hip replacements (THR). Clinically relevant in vitro simulations of wear are essential to predict the osteolytic potential of bearing surfaces in artificial hip joints. Newborn calf or bovine serum has been accepted as a boundary lubricant for such in vitro tests, but its biological stability has been questioned. This study compared the wear factors, number of wear particles and levels of microbial contamination produced in bovine serum and a gelatin-based lubricant. The wear factors produced by the two lubricants were not significantly different, however the wear debris morphology produced was substantially different. The bovine serum became contaminated with micro-organisms within 28 h, whereas the protein-based lubricant remained uncontaminated. The results showed that bovine serum was not a stable boundary lubricant. They also showed that although the wear factors for the two solutions were not significantly different, the protein-based lubricant was not a suitable alternative to bovine serum because the wear debris produced was not clinically relevant.
The variation in the orientations and moment arms of the knee extensor and flexor muscle tendons with increasing muscle force: A mathematical analysis
Authors: Imran A , Huss R A , Holstein H , O'Connor J J 
Published: October 2002

The orientations and moment arms of the knee extensor and flexor muscle tendons are evaluated with increasing values of muscle force during simulated isometric exercises. A four-bar linkage model of the knee in the sagittal plane was used to define the motion of the joint in the unloaded state during 0–120° flexion. The cruciate and collateral ligaments were represented by arrays of elastic fibres, which were recruited sequentially under load or remained buckled when slack. A bi-articular model of the patello-femoral joint was used. Simple straight-line representation was used for the lines of action of the forces transmitted by the model muscle tendons. The effects of tissue deformation with increasing muscle force were considered. During quadriceps contraction resisted by an external flexing load, the maximum change in moment arm of the patellar tendon was found to be 2 per cent at 0° flexion when the quadriceps force was increased tenfold, from 250 to 2500 N. The corresponding maximum change in orientation of the tendon was 3° at 120° flexion. During hamstrings contraction resisted by an external extending load, the maximum change in moment arm of the hamstrings tendon was 8 per cent at 60° flexion when the hamstrings force was increased tenfold, from 100 to 1000 N. During gastrocnemious contraction, the corresponding maximum change for the gastrocnemious tendon was 3 per cent at 0°. The orientations of the flexor muscle tendons in this range of force either remained constant or changed by 1° or less at any flexion angle. The general trend at any flexion angle was that, as the muscle force was increased, the moment arms and the orientations approached nearly constant values, showing asymptotic behaviour. It is concluded that experimental simulations of knee muscle action with low values of the externally applied load, of the order of 50 N, can provide reliable estimates of the relationships between muscle forces and external loads during activity.
The effect of kinematic conditions on the wear of ultra-high molecular weight polyethylene (UHMWPE) in orthopaedic bearing applications
Authors: Cornwall G B , Bryant J T , Hansson C M 
Published: October 2002

It is known that wear mechanisms differ between the ultra-high molecular weight polyethylene (UHMWPE) components of total hip replacement (THR) and total knee replacement (TKR). The difference in relative contact position or ‘kinematic conditions of contact’ between the metal and polymer components is thought to contribute to the contrast in observed wear mechanisms. A reciprocating wear tester was used to evaluate three basic kinematic contact conditions: sliding, in which the relative contact position on the polymer remains stationary; gliding, where the contact position on the polymer reciprocates; and rolling, where the contact position on the polymer varies and the relative velocities of both components are equal. All static load tests used cast Co—Cr alloy and irradiated Chirulen® UHMWPE in a 37 °C environment lubricated with bovine serum albumin. UHMWPE test sample wear was measured gravi-metrically at intervals of 600000 cycles. The results indicated a difference in wear factor (volume lost due to wear per unit load per unit sliding distance) between the three groups with varying relative motion. The study indicates that screening tests which evaluate wear properties of new materials for total joint replacement should reflect the different kinematic contact conditions.
Quantification of third body damage to the tibial counterface in mobile bearing knees
Authors: Jones V C , Williams I R , Auger D D , Walsh W , Barton D C , Stone M H , Fisher J 
Published: October 2002

Fourteen pairs of explanted low contact stress (LCS) tibial interface components: six rotating platform (RP), six meniscal (MN) and two anterior-posterior (AP) glide designs, have been analysed with particular attention paid to the condition of the tibial counterfaces. The average surface roughness, Ra, for the tibial trays ranged from 0.01 to 0.087 μm, significantly greater than the unworn control measurement of 0.008 μm. The scratch geometry analysis showed that the scratch peaks were found to be consistently of a lower aspect ratio than the scratch valleys and under 1 μm in height (average asperity height - Rp = 0.52 μm, aspect ratio Δ p = 0.01, average asperity depth Rv = 1.10 μm, Δ v = 0.05). The largest scratches were 3-4 μm in both Rp and Rv In vitro tests have shown that ultra-high molecular weight polyethylene (UHMWPE) wear increases in the presence of counterface scratches perpendicular to the direction of motion. In these explants, the unidirectional motion produced scratches parallel to the direction of sliding which is predicted to produce a smaller increase in UHMWPE wear. Other designs in mobile bearing knees have less constrained motion at the tibial counterface and this has been shown to accelerate wear; it may also lead to a further increase in wear in the presence of third body scratches. It may be possible in future knee designs to reduce this type of wear damage by introducing alternative materials or coatings which are more resistant to scratching and surface roughening.
A fracture movement monitoring system to aid in the assessment of fracture healing in humans
Authors: Ogrodnik P J , Moorcroft C I , Thomas P B M 
Published: October 2002

This paper presents a new design for a device to monitor the motion of fracture fragments in diaphyseal tibial fractures. The device measures the motion that occurs at the fracture site when loaded by gait or by manipulation. It has undergone rigorous calibration and acceptance trials. The device has been used in ethically approved research clinics held at the North Staffordshire Hospital (40 patients). The paper presents a selection of results obtained using the new device. The results demonstrate several new ways of assessing fracture healing by examining fracture site motion. The following conclusions were drawn: 1. If fracture monitoring devices are to be attached to bone screws, it is essential to minimize bone screw errors. To do this, each patient must have similar bone screw lengths, orientations, alignment and siting. This is only achievable using a peroperative reduction device. 2. If fracture stiffness is to be used as a measure of fracture healing, load rate should be controlled; at the very least strain rate should be controlled. 3. It is imperative that fracture stiffness be measured in more than one plane by a biplanar device so that asymmetry may be accommodated. 4. Fracture stiffness, on its own, is probably not a sufficiently rigorous measure of healing end-point. The quantifiably viscoelastic properties of healing callus should be taken into account.
Interface biomechanics of the Anca Dual Fit hip stem: An in vitro experimental study
Authors: Monti L , Cristofolini L , Viceconti M 
Published: October 2002

The Anca Dual Fit hip stem (Cremascoli Wright, Milan, Italy) is a partially cemented stem developed to overcome the drawbacks of both cemented and uncemented fixations. Its design was based on the hypothesis that partial cementing would ensure the primary stability necessary to allow bone ingrowth on the cement-free stem surfaces. At the same time, the limitation of the cement to the proximal regions would prevent stress-shielding by increasing proximal load transfer. After finite element (FE) simulations and in vitro primary stability assessment, an analysis of the long-term stability of the Anca Dual Fit stem was necessary to conclude the preclinical testing. Three stems were implanted in composite femurs and subjected to testing for 1 × 106 cycles, each cycle reproducing the activity of stair climbing. The simulation was designed so as to replicate the physiological loading in a simplified, yet relevant way for this test. Various measurements were collected before, during and after the test in order to give exhaustive information on the response of the implant to long-term, cyclic loading. The present study confirmed the positive results of previous investigations, and proved that the Anca Dual Fit stem has excellent long-term stability; therefore successful clinical outcomes are predicted.
A technique for measuring the compressive modulus of articular cartilage under physiological loading rates with preliminary results
Authors: Shepherd D E T , Seedhom B B 
Published: October 2002

This paper describes a technique and apparatus for measuring the compressive modulus of articular cartilage under physiological loading rates. The compressive modulus is the most relevant property to the primary function of articular cartilage i.e. load carriage. It has been determined previously from measurement of cartilage deformation under slow or almost static loading conditions. The modulus was based on deformations occurring 2 s after the initial application of load which greatly reduces its relevance since in physiological conditions joint loading occurs within 10-150 ms. Five human knee joints have been used to test the apparatus before a major study is undertaken. The preliminary results from these joints showed that the compressive modulus of articular cartilage measured within physiological loading time intervals was much greater than previously reported. The compressive modulus at 20 ms was in the range 4.4-27 MPa and was between 32 and 75 per cent greater than its value obtained at 2 s after loading.
Computer simulation of the dynamics of a human arm and orthosis linkage mechanism
Authors: Buckley M A , Johnson G R 
Published: October 2002

This paper describes the use of computer modelling and simulation during the design and development of a motorized upper limb orthotic system to be used to aid the dysfunctional human arm. The orthosis consisted of a three-degree-of-freedom shoulder module and a lower arm module providing movements at the elbow and wrist. Simulation software has been used to model the mechanism created by the connection of the orthosis and the arm. With this model it has been possible to analyse the kinematics and kinetics of both the arm and orthosis during a variety of dynamic loading conditions. In particular, the power requirements of the orthotic joints during the execution of specific tasks have been determined and these data have been used to specify the motors of a working prototype. The effect of misalignment between real and orthotic shoulder joints has also been investigated and a potentially hazardous situation has been highlighted prior to testing of the prototype by a volunteer in the laboratory.
Evaluation of the frictional properties of an elastomer with enhanced lipid-adsorbing ability
Authors: Williams P F , Iwasaki Y , Ishihara K , Powell G L , Gilbert J A , Nakabayashi N , LaBerge M 
Published: October 2002

Wear particle production in load-bearing orthopaedic implants is one of the major factors currently limiting the service life of the implant. Most of the research carried out to date in attempting to solve this problem has used the approach of finding more wear-resistant biocompatible material pairs. In contrast, other researchers have attempted to reduce wear by encouraging elastohydrodynamic film formation through the use of elastomeric bearing surfaces. Unfortunately, these elastomeric bearing surfaces have poor tribological properties when a fluid film is not present. Boundary lubrication of an elastomeric orthopaedic bearing may alleviate some of these difficulties. The purpose of this research was to fabricate and characterize an elastomeric material that had a surface capable of specifically adsorbing a naturally occurring boundary lubricant. Dipalmitoyl phosphatidylcholine (DPPC) has been previously shown to be able to act as a boundary lubricant at stresses that occur in human load-bearing joints such as the hip and knee; therefore, DPPC was chosen for use in this study. It was expected that in an aqueous liposome suspension the static coefficient of friction μs of such a material would be lower, and increase less quickly over time, than a similar material without an ability to adsorb specifically DPPC when articulated against a polished chrome steel ball bearing. The lipid-adsorbing elastomer did not possess the desired tribological properties. This result was attributed to the polymer adsorbing the DPPC in the liposome phase and not in the bilayer phase, and interaction among the polymeric surface, DPPC and water. This approach to lubricating orthopaedic bearings was shown to have some merit, but a great deal of work needs to be done before such an approach can be used on a clinically available material.
Further studies into proximal interphalangeal joint dimensions for the design of a surface replacement prosthesis: Medullary cavities and transverse plane shapes
Authors: Ash H E , Unsworth A 
Published: October 2002

The proximal and middle phalanges from 83 proximal interphalangeal joints (PIPJs) were set in clear plastic and sectioned in the transverse plane leaving the heads whole. The sections were cleaned, shadowgraphed and measured. The medullary canals were marked on sagittal and frontal plane shadowgraphs of the intact bones and analysed. The information was then used in the design of a surface replacement prosthesis for the PIPJs. The main dorsal surface of the proximal phalanx (PP) was found to be angled to the longitudinal baseline of the bone by a mean of 5.19°. This angle increased just proximal to the phalangeal head to a mean of 11.84°. The mean ratio between these angles was 2.71. The phalangeal shaft bone was thicker laterally than dorsally and palmarly, and thicker dorsally than palmarly for the proximal and middle phalanges throughout the length of the bone. The shape and size of the transverse cross-section of the medullary canal changed throughout the length of the shaft. The centreline of the PP medullary canal coincided with the midline of the bone in the frontal plane and was approximately a straight line along the length of the canal. In the sagittal plane the centreline was slightly palmar to the midline and the angle between it and the longitudinal baseline of the bone changed along the length of the canal. In the region of the shaft just proximal to the PP head (where the stem of a surface replacement prosthesis would fit) the mean angle was 10.63°. The centreline was offset dorsally from the centre of rotation of the PIPJ by a mean of 0.83 mm, 0.83 mm, 0.80 mm and 0.57 mm for the index, middle, ring and little fingers respectively, with an overall mean of 0.76 mm. The mean PP head heights (transverse plane) were 9.17 mm, 9.33 mm, 8.73 mm and 7.40 mm and the mean PP widths (transverse plane) were 12.86 mm, 13.25 mm, 12.75 mm and 10.54 mm for the index, middle, ring and little fingers respectively. The mean angle between the lateral sides of the condyles to the transverse baseline was 78.35° and the mean distance from the centreline of the PP head (transverse plane) to the bases of the two condyles was 4.69 mm. The mean maximum depth of the PP head intercondylar sulcus in the frontal plane was 0.72 mm and in the transverse plane, the mean maximum depth of the intercondylar sulcus on the anterior face was 0.82 mm.
In vitro simulation of contact fatigue damage found in ultra-high molecular weight polyethylene components of knee prostheses
Authors: Currier J H , Duda J L , Sperling D K , Collier J P , Currier B H , Kennedy F E 
Published: October 2002

An in vitro simulation of fatigue loading of ultra-high molecular weight polyethylene (UHMWPE) knee components was carried out on a knee simulator and on a rolling and sliding wear tester. Tibial components for the knee simulator were gamma-sterilized, implantable components taken from manufacturing inventory. The rolling/sliding UHMWPE discs were machined from bar stock and either gamma sterilized in air and accelerated aged, or left as non-sterilized (controls). Cracking and delamination of samples that had been gamma sterilized in air and aged were observed in both types of tests. Contact fatigue damage was visible in as few as 150 000 cycles using the knee simulator at loads of 122 N (275 lb). The rolling/sliding samples showed signs of damage in as few as 130 000 cycles with an estimated stress of 15 MPa and 25 per cent sliding. However, cracking and delamination were not generated in the never-sterilized or recently sterilized controls. UHMWPE that has been gamma sterilized in air and aged is shown to be susceptible to contact fatigue damage. These results are important to the interpretation of in vitro total knee replacement simulations used to assess the performance of tibial bearings.
Sliding wear studies of selected nitride coatings and their potential for long-term use in orthopaedic applications
Authors: Ward L P , Subramanian C , Strafford K N , Wilks T P 
Published: October 2002

In the area of orthopaedic implants, particularly total hip joint replacements, a metal-plastic combination is still the most popular choice consisting of a femoral head fabricated from 316L stainless steel, Ti alloy or Co-Cr alloy in contact with an ultra-high molecular weight polyethylene (UHMWPE) acetabular cup. It is recently considered that wear of the UHMWPE cup is of major concern. Generation of the wear debris can have adverse effects on the body, both localized and systemic. It is envisaged that wear of the prosthetic components, particularly those fabricated from UHMWPE can be reduced through the use of surface coatings. The aim of this investigation was to deposit a selection of refractory element nitride-based coatings (TiN, TiAIN, ZrN) onto 316L stainless steel substrates, using physical vapour deposition (PVD) technology and to study their sliding wear behaviour in contact with both UHMWPE and 316L stainless steel pins, using a pin-on-plate testing rig. Tests were conducted in Ringers solution and Ringers solution plus bone cement particles. The volume of material removed from the pins served as an indication of their wear behaviour. Wear mechanisms were identified using scanning electron microscopy. The results of these findings and the potential for these coatings to be used in orthopaedic applications are discussed.
Theoretical estimates of cruciate ligament forces: Effects of tibial surface geometry and ligament orientations
Authors: Imran A , O'Connor J J 
Published: October 2002

A mathematical model of the knee in the sagittal plane was used to analyse the effect of tibial surface geometry and ligament orientations on the estimates of cruciate ligament forces. An elementary mechanical analysis was used to calculate the ligament forces L during a simulated antero-posterior (A-P) laxity test (passive test), and during isometric quadriceps contraction (IQE). Three sets of anatomical parameters (sites of bony attachments and lengths of the ligaments) were used from the literature. Flat, concave and convex shapes were considered for the tibial plateau articulating with a compatible convex femoral condyle. Also, the effects of position and posterior tilt of the tibial plateau were analysed for the concave and flat surfaces. The analysis showed that the ligament forces rose steeply as they approached collinearity with the contact force, C. For a flat tibia, the direction of C remained independent of flexion angle or position of the tibial plateau. For the concave tibia, the direction of C varied with flexion as well as with position of the centre of curvature, O, of the tibial plateau. C had an anterior component synergistic with the posterior cruciate ligament (PCL) when the point of contact, F, was anterior to O. On the other hand, C had a posterior component synergistic with the anterior cruciate ligament (ACL) when F was posterior to O. Also, posterior tilt of the flat or concave surfaces resulted in an increase in the anterior component of C. The effects of the convex tibial surface were opposite to those of the concave surface. During the A-P laxity test, the ligament forces arising from the concave tibia were very sensitive to the A-P position of O and to the posterior tilt of the plateau which allowed C and L to approach collinearity. Proximo-distal movement of O had a relatively insignificant effect on the ligament force. Similarly, compared to the concave surface, the posterior tilt of the flat tibia had a lesser effect on the ligament forces. Compared to the passive test, use of the muscle forces during IQE resulted in larger ligament forces, though the trends in force behaviour over the flexion range remained the same. The analysis emphasizes the importance of correct graft placement during ligament reconstruction, and the need to avoid steep inclination (more than 70° to tibial plateau). Increasing the inclination from 70 to 80° doubles the ligament force. Further, the analysis suggests that, in bicompartmental knee replacement, the efficacy of concave surfaces in replacing cruciate ligament function depends critically on the horizontal placement of the tibial component and its orientation about the mediolateral axis.