bluuebunny/crossref_metadata_2025_split huggingface dataset:
Establishing altruistic ethics to use technology for Social Welfare—How Japan manages Web3 and self-sovereign identity in local communities
Authors: Kim Daum , Kokuryo Jiro 
Published: January 2024

AbstractTechnologies of self-sovereign identity (SSI) and Web3 tools that strongly protect individual autonomy, combined with the ethics of Asian altruism, can effectively guide the governance of the emerging cyber civilization. In contrast, governance in Western industrial civilization stresses the pursuit of individual self-interest and struggles to balance the benefits of big tech with the protection of individual dignity and the preservation of the common good. We demonstrate, with reference to a local community in Japan, that SSI is successful in encouraging communal collaboration and well-being while providing individuals with greater control over their personal data. We also show that Web3 tools provide incentives for altruistic behaviors while safeguarding SSI. Integration of SSI and social protection demonstrates the potential for building an information society grounded in altruistic values, honoring individual dignity, and recognizing the government’s role in protecting social welfare. Ultimately, this research unveils how altruistic values can be fostered through SSI and Web3.
Phytochemical analysis, antimicrobial, antioxidant, and cytotoxicity activities of Schinus molle (L.) extracts
Authors: M. E. Shehata , El-Sherbiny Gamal M. , Sharaf Mohamed H. , Kalaba Mohamed H. , Shaban Abdelghany S. 
Published: January 2024

Abstract

Schinus molle seeds and leaves are frequently employed in traditional medicine to treat a range of diseases. This study aims to explore the potential of Schinus mole (L.) seed and leaf extracts in terms of their phytochemical constituents and antimicrobial, antioxidant, and cytotoxic activities. The study utilized GC-MS spectroscopy, antimicrobials, antioxidants, and cytotoxicity techniques to evaluate the extracts. The result of phytochemical analysis revealed that Schinus molle seed extract contains seven peaks with a major compound, bis (2-ethylhexyl) phthalate (59.11%), followed by n-hexadecanoic acid (10.84), while Schinus molle leaf extract exhibits sixteen peaks with a main compound, squalene (16.87%), followed by azulene (14.88%) and lupeol (12.4%). The Schinus molle seeds and leaf exhibited the high antimicrobial activity with inhibition zones ranging from 15 ± 0.57 to 27.33 ± 0.88 mm against tested microorganisms. In addition, it was investigated that the minimum inhibitory concentrations (MICs) of different extracts against microbial strains, including Bacillus cereus, Klebsiella pneumoniae ATCC 13883, and Cryptococcus neoformans, were found to be 62.5 μg/ml, while Staphylococcus aureus (MRSA) has a MIC of 125 μg/ml with seed extract and 250 μg/ml with leaf extract. The other strains, including Escherichia coli, Salmonella typhimurium, and Pseudomonas aeruginosa, have a MIC of 500 μg/ml in both seed and leaf extracts. Schinus molle seeds and leaf exhibited considerable antioxidant action compared with ascorbic acid. Moreover, significant variation in the effects on Allium cepa root tips was observed upon treatment with Schinus molle seed and leaf extracts. The mitotic index in the group receiving Schinus molle seed and leaf extract showed a significant decrease when compared to the control cells. This decrease was based on the duration and dosage of exposure. On the other hand, there was a clear increase in the occurrence of chromosomal abnormalities. Finally, the findings showed that Schinus molle seed and leaf extract exhibit antibacterial, antioxidant, and anticytotoxic activities and revealed that they are a significant source of bioactive compounds with the possibility of use in biomedical applications.
Enhancing Reproducibility in Precipitate Analysis: A FAIR Approach with Automated Dark-Field Transmission Electron Microscope Image Processing
Authors: Zia Ghezal Ahmad Jan , Hanke Thomas , Skrotzki Birgit , Völker Christoph , Bayerlein Bernd 
Published: January 2024

AbstractHigh-strength aluminum alloys used in aerospace and automotive applications obtain their strength through precipitation hardening. Achieving the desired mechanical properties requires precise control over the nanometer-sized precipitates. However, the microstructure of these alloys changes over time due to aging, leading to a deterioration in strength. Typically, the size, number, and distribution of precipitates for a quantitative assessment of microstructural changes are determined by manual analysis, which is subjective and time-consuming. In our work, we introduce a progressive and automatable approach that enables a more efficient, objective, and reproducible analysis of precipitates. The method involves several sequential steps using an image repository containing dark-field transmission electron microscopy (DF-TEM) images depicting various aging states of an aluminum alloy. During the process, precipitation contours are generated and quantitatively evaluated, and the results are comprehensibly transferred into semantic data structures. The use and deployment of Jupyter Notebooks, along with the beneficial implementation of Semantic Web technologies, significantly enhances the reproducibility and comparability of the findings. This work serves as an exemplar of FAIR image and research data management.
Reconstructing Microstructures From Statistical Descriptors Using Neural Cellular Automata
Authors: Seibert Paul , Raßloff Alexander , Zhang Yichi , Kalina Karl , Reck Paul , Peterseim Daniel , Kästner Markus 
Published: January 2024

AbstractThe problem of generating microstructures of complex materials in silico has been approached from various directions including simulation, Markov, deep learning and descriptor-based approaches. This work presents a hybrid method that is inspired by all four categories and has interesting scalability properties. A neural cellular automaton is trained to evolve microstructures based on local information. Unlike most machine learning-based approaches, it does not directly require a data set of reference micrographs, but is trained from statistical microstructure descriptors that can stem from a single reference. This means that the training cost scales only with the complexity of the structure and associated descriptors. Since the size of the reconstructed structures can be set during inference, even extremely large structures can be efficiently generated. Similarly, the method is very efficient if many structures are to be reconstructed from the same descriptor for statistical evaluations. The method is formulated and discussed in detail by means of various numerical experiments, demonstrating its utility and scalability.
Anxiety Prevalence in Youth with Autism: A Systematic Review and Meta-analysis of Methodological and Sample Moderators
Authors: Thiele-Swift Henry Noah , Dorstyn Diana-Santa 
Published: January 2024

AbstractResearch on the prevalence of anxiety in children and adolescents with autism remains fragmented due to a reliance on help-seeking populations and differences in anxiety assessment. We present the pooled findings from 15 community studies (N = 4459) sourced from the Embase, PubMed, and PsycINFO databases (1970–2023). Equally high rates of anxiety symptoms and disorders were identified via self-report (33%, CI = 25 to 40%) and diagnostic interview (19%, CI = 7 to 40%). Higher IQ and male gender were identified as significant covariates, although these results may reflect sampling biases. The findings highlight the need for routine screening, with multiple informants, and improved sampling methods. Protocol was registered on Open Science Framework (https://osf.io/7mtca/).
Ketogenic nutritional therapy (KeNuT)—a multi-step dietary model with meal replacements for the management of obesity and its related metabolic disorders: a consensus statement from the working group of the Club of the Italian Society of Endocrinology (SIE)—diet therapies in endocrinology and metabolism
Authors: Barrea L. , Caprio M. , Camajani E. , Verde L. , Perrini S. , Cignarelli A. , Prodam F. , Gambineri A. , Isidori A. M. , Colao A. , Giorgino F. , Aimaretti G. , Muscogiuri G. 
Published: January 2024

Abstract
Purpose
The ketogenic nutritional therapy (KeNuT) is an effective dietary treatment for patients with obesity and obesity-related comorbidities, including type 2 diabetes, dyslipidaemia, hypertension, coronary artery disease, and some type of cancers. However, to date an official document on the correct prescription of the ketogenic diet, validated by authoritative societies in nutrition or endocrine sciences, is missing. It is important to emphasize that the ketogenic nutritional therapy requires proper medical supervision for patient selection, due to the complex biochemical implications of ketosis and the need for a strict therapeutic compliance, and an experienced nutritionist for proper personalization of the whole nutritional protocol.

Methods
This practical guide provides an update of main clinical indications and contraindications of ketogenic nutritional therapy with meal replacements and its mechanisms of action. In addition, the various phases of the protocol involving meal replacements, its monitoring, clinical management and potential side effects, are also discussed.

Conclusion
This practical guide will help the healthcare provider to acquire the necessary skills to provide a comprehensive care of patients with overweight, obesity and obesity-related diseases, using a multistep ketogenic dietary treatment, recognized by the Club of the Italian Society of Endocrinology (SIE)—Diet Therapies in Endocrinology and Metabolism.
Hydrologic Extremes in a Changing Climate: a Review of Extremes in East Africa
Authors: Taye Meron Teferi , Dyer Ellen 
Published: January 2024

Abstract

Purpose
Eastern Africa has a complex hydroclimate and socio-economic context, making it vulnerable to climate change-induced hydrological extremes. This review presents recent research on drivers and typologies of extremes across different geographies and highlights challenges and improvements in forecasting hydrological extremes at various timescales.

Recent Findings
Droughts and floods remain the major challenges of the region. Recently, frequent alterations between droughts and floods have been a common occurrence and concern. Research underlines the heterogeneity of extremes and the impact of climate change as increased intensity and duration of extremes. Moreover, the importance of local and antecedent conditions in changing the characteristics of extremes is emphasized.

Summary
A better understanding of these drivers and how they interact is required. Observational and modeling tools must capture these relationships and extremes on short timescales. Although there are improvements in forecasting these extremes, providing relevant information beyond meteorological variables requires further research.
The Role of Male Consent in Assisted Reproductive Technology Procedures: an Examination of Japanese Court Cases
Authors: Muraoka Yuko , Kokado Minori , Kato Kazuto 
Published: January 2024

AbstractWith the development of assisted reproductive technologies, medical, ethical, legal, and social issues have arisen that did not exist when natural conception was the only means of childbirth. In Japan, men tend to believe that assisted reproductive technologies are not directly related to them, with the literature showing that men are often reluctant to be involved in fertility treatment processes. To better understand this situation, this study analyzes the role of male consent during assisted reproductive technology procedures in Japan. First, we examined Japanese court cases that dealt with issues related to male consent during assisted reproductive technology procedures and identified three situations in which problems related to male consent during such procedures may arise. Next, we analyzed the background of such issues and the implications of the lack of consent regarding men’s reproductive rights. Finally, we explored the need for legislation on assisted reproductive technologies. The study concludes that discussions on the scope of male partner rights in assisted reproductive technology procedures are key for minimizing unnecessary conflict between partners, thus ensuring both the rights of women who wish to have children and the welfare of their children.
Antioxidant, Cytotoxicity, and Anti-inflammation Activities of Phenanthroline Adducts of Zn(II) and Ni(II) bis(N-alkyl-N-phenyldithiocarbamate)
Authors: Saiyed Tanzimjahan A. , Adeyemi Jerry O. , Singh Moganavelli , Onwudiwe Damian C. 
Published: January 2024

AbstractIn this study, 4,7-diphenyl-1,10-phenanthroline adducts of Ni(II) and Zn(II) of N-methyl or ethyl-N-phenyldithiocarbamate were synthesized and the final adducts were represented as [Zn(L1)2L3], [Zn(L2)2L3], [Ni(L1)2L3], [Ni(L2)2L3] (where L1 = methyl, L2 = ethyl, L3 = bathophenanthroline) and characterized using various spectroscopic techniques and elemental analysis. Both the FT-IR and NMR analysis suggest that all the adducts possessed six coordination geometry by the metal atom centres upon the emergence of a new M-N bond. This was shown by the changes observed in the peaks and chemical shifts of the adducts in comparison to the parent complexes. The cytotoxicity, antioxidant, and anti-inflammatory properties were evaluated using different assays to ascertain their biological properties. In all the assays, no noticeable trend was observed between the adducts of similar ligands and metals. Nevertheless, in the antioxidant assays, a good to moderate activity was observed, especially in the DPPH assay, which gave the best radical scavenging properties. Additionally, the estimated IC50 values of 0.011 and 14.76 µM were calculated for the cytotoxicity in the human cervical cancer (HeLa) cell line for both [Zn(L1)2L3] and [Ni(L2)2L3] adducts, respectively, in comparison to 5-Flurouracil (17.48 µM). On the other hand, very low cytotoxicity was found for most of the adducts in the embryonic kidney 293 (HEK 293) cell lines, especially for [Zn(L1)2L3], demonstrating its superior amongst the other adduct and the standard drug. Moreover, the adducts exhibited good to moderate anti-inflammatory properties compared to diclofenac, a controlled drug. These findings thus suggest that the adducts, particularly [Zn(L1)2L3], hold promise as potential anticancer agents and warrant further evaluation through clinical trials.
Understanding Consumer Attitudes Towards Sustainable Business Models—A Qualitative Study with Finnish Consumers
Authors: Vehmas Kaisa , Bocken Nancy , Tuovila Hannamaija 
Published: January 2024

AbstractSustainable business models have been presented in the literature as a way to gain stepwise improvements in environmental impact compared to just selling a product, and many companies have started experimenting with them. However, these models are not yet scaled up across sectors. One of the barriers is understanding how consumers perceive sustainable business models and how much they would be ready to pay products and services from sustainable offerings. To this extent, our study investigated the following research questions: How do consumers perceive the sustainability attributes of novel sustainable business models? How does this affect consumer willingness to pay (WTP) for the offering provided? This study uses a qualitative research approach, conducting online discussions among 44 Finnish consumers. Finland is in focus as it has a top ranking in sustainability country indexes. Through the study, it was found that consumers pay attention to sustainability of the products and services they consume. They are willing to use available information and assess this to make sustainable purchasing decisions. However, they lack trustworthy information and sometimes it is too time-consuming to find the data. When making purchasing decisions, consumers perceive certain positive environmental and social impacts. However, the environmental and social impact of the studied business models did not turn into consumer WTP especially when considering expensive products, or business models with a social impact only. Still, in general, over half of the participants are willing to pay more about responsible produced products.
Perceived usefulness of mobile devices in assessment: a comparative study of three technology acceptance models using PLS-SEM
Authors: Ortiz-López Alberto , Sánchez-Prieto José Carlos , Olmos-Migueláñez Susana 
Published: January 2024

AbstractThe use of digital media in education has already been addressed in numerous technology acceptance models, but there is very little research on establishing a link between acceptance and assessment using mobile devices, a reality in educational institutions. This work aims to extend research by developing the TAM model and studying teachers’ perceived usefulness of mobile devices in terms of how they understand assessment: generically, as a summative and a formative assessment, or as the complementarity of these. This study proposes a comparison between three models using the partial least squares structural equation modeling (PLS-SEM) on a sample of 262 master’s degree students (pre-service teachers). The results show the validity of the three proposals and confirm the advantages to specifically consider assessment in acceptance models, as well as the importance of addressing its modalities differently after obtaining better results in the two models that do so. The study also confirms the importance of self-efficacy in the use of mobile devices as a predictor of usefulness and intention to use in the three models. The use of a comparative approach and the development of the perceived usefulness construct in assessment represents a new contribution to the field of acceptance studies.
Evaluation of the long-term outcomes of the University of Michigan’s Practice-Oriented Research Training (PORT) program
Authors: Ianni Phillip A. , Samuels Elias M. , Eakin Brenda L. , Champagne Ellen , Kalpakjian Claire Z. , Murphy Susan L. 
Published: January 2024

Abstract
The University of Michigan created the Practice-Oriented Research Training (PORT) program and implemented it between 2008 and 2018. The PORT program provided research training and funding opportunities for allied healthcare professionals. The program consisted of weekly didactics and group discussion related to topics relevant to developing specific research ideas into projects and funding for a mentored research project for those who submitted a competitive grant application. The goal of this evaluation was to assess the long-term impact of the PORT program on the research careers of the participants. Ninety-two participants (74 staff and 18 faculty) participated in both phases of the program. A mixed-methods approach to evaluation was used; 25 participants who received funding for their research completed surveys, and semi-structured interviews were conducted with eight program participants. In addition, data were collected on participants’ publication history. Fifteen out of the 74 staff participants published 31 first-authored papers after participating in PORT. Twelve out of 15 staff participants who published first-authored papers did so for the first time after participating in the PORT program. Results of quantitative and qualitative analyses suggest that the PORT program had positive impacts on both participants and the research community.
Is team science valued in the academic promotions process? A mixed-methods case study
Authors: Potter Michael B. , Mansur Saji , Rutman Shira P. , Brindis Claire D. 
Published: January 2024

Abstract

Introduction:
Traditionally, research institutions have valued individual achievements such as principal investigator and lead authorship status as primary indicators in the academic promotions process. However, the scientific process increasingly requires collaboration by teams of researchers across multiple disciplines, sometimes including experts outside academia, often referred to as “team science.” We sought to determine whether there is agreement about what constitutes team science at our academic institution and whether current promotion processes sufficiently incentivize faculty participation in team science.

Methods:
We conducted 20 qualitative interviews with academic leaders (N = 24) at the University of California, San Francisco (UCSF) who supervise faculty promotions processes. Participants were asked to share their definitions of team science and the extent to which faculty receive credit for engaging in these activities during the promotions process. A subset of participants also completed a brief survey in which they ranked the importance of participation in team science relative to other factors that are traditionally valued in the promotions process. Interview data were examined by two analysts using structural coding. Descriptive analyses were conducted of survey responses.

Results:
Though team science is valued at UCSF, definitions of team science and the approach to assigning credit for team science in academic promotions processes varied widely. Participants suggested opportunities to bolster support for team science.

Conclusions:
Efforts to define and provide transparent faculty incentives for team science should be prioritized at institutions, like UCSF, seeking to advance faculty engagement in collaborative research.
The exact consistency strength of the generic absoluteness for the universally Baire sets
Authors: Sargsyan Grigor , Trang Nam 
Published: January 2024

Abstract
A set of reals is universally Baire if all of its continuous preimages in topological spaces have the Baire property.

$\mathsf {Sealing}$

is a type of generic absoluteness condition introduced by Woodin that asserts in strong terms that the theory of the universally Baire sets cannot be changed by forcing.
The

$\mathsf {Largest\ Suslin\ Axiom}$

(

$\mathsf {LSA}$

) is a determinacy axiom isolated by Woodin. It asserts that the largest Suslin cardinal is inaccessible for ordinal definable bijections. Let

$\mathsf {LSA-over-uB}$

be the statement that in all (set) generic extensions there is a model of

$\mathsf {LSA}$

whose Suslin, co-Suslin sets are the universally Baire sets.
We show that over some mild large cardinal theory,

$\mathsf {Sealing}$

is equiconsistent with

$\mathsf {LSA-over-uB}$

. In fact, we isolate an exact large cardinal theory that is equiconsistent with both (see Definition 2.7). As a consequence, we obtain that

$\mathsf {Sealing}$

is weaker than the theory ‘

$\mathsf {ZFC} +$

there is a Woodin cardinal which is a limit of Woodin cardinals’.
A variation of

$\mathsf {Sealing}$

, called

$\mathsf {Tower\ Sealing}$

, is also shown to be equiconsistent with

$\mathsf {Sealing}$

over the same large cardinal theory.
The result is proven via Woodin’s

$\mathsf {Core\ Model\ Induction}$

technique and is essentially the ultimate equiconsistency that can be proven via the current interpretation of

$\mathsf {CMI}$

as explained in the paper.