bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does Political Trust Matter? A Meta-analysis on the Consequences of Trust
Authors: Devine Daniel 
Published: February 2024

AbstractPolitical trust has long been seen as fundamental for societal cooperation and democratic legitimacy. However, evidence about its consequences are partial and fragmented, and we do not currently have a systematic understanding of whether political trust warrants such vast attention. This paper conducts a systematic review and meta-analysis of 61 studies reporting 329 coefficients derived from over three and a half million observations globally. After synthesising the conceptual and theoretical frameworks in the extant literature, the meta-analysis results show that trust is weakly to moderately related to outcomes as diverse as voter turnout, vote choice, policy preferences and compliance, but is unrelated to informal participation. These results are robust to a range of considerations such as the measurement of trust, modelling strategy, region of study, publication bias, and design of the study. The review also highlights substantial geographical and methodological gaps, particularly the reliance on cross-sectional designs. Substantively, the results show that trust is importantly and robustly related to what people want from their political systems and how they interact with it. By systematically analysing the extant research, the paper provides a robust, systematic, and empirical foundation to advance research on political trust.
After a Storm Come Votes: Identifying the Effects of Disaster Relief on Electoral Outcomes
Authors: Fukumoto Kentaro , Kikuta Kyosuke 
Published: February 2024

AbstractThe retrospective voting theory suggests that citizens vote for governing parties in response to distributive benefits. Knowing this, governments may reward voters by providing particularistic benefits—i.e., pork—prior to elections. Previous studies, however, do not account for the endogeneity. We address this problem by focusing on disaster relief and exploiting exogeneity of disaster. In particular, by using maximum hourly rainfall as an instrumental variable for disaster relief, we analyze the causal effect of disaster relief on incumbent’s electoral outcomes. Our analyses of Japanese data in the past few decades indicate that disaster relief increased governing parties’ vote share. Specifically, when the disaster relief per capita increases from zero to its mean, the predicted value of the governing parties’ vote share increases by 2.8 and 5.4% points in the lower and upper chambers, respectively. The finding is consistent with retrospective voting behavior. Moreover, our results imply that the incumbent’s electoral gain is brought about by persuading voters from oppositions to governing parties rather than by mobilizing supporters of governing parties.
The implementation of writing pedagogies in the Write to Read intervention in low-SES primary schools in Ireland
Authors: Kennedy Eithne , Shiel Gerry 
Published: February 2024

AbstractThis study describes the initial implementation of the writing component of the Write to Read (W2R) literacy intervention in eight low-SES (socio-economically disadvantaged) elementary-level urban schools. Through customised onsite professional development provided by coaches, the writing component sought to build teachers’ capacity to design and implement a writing workshop framework infused with research-informed practices for writing suitable for their school and classroom contexts, including attention to cognitive, social and affective dimensions. The paper draws on quantitative and qualitative questionnaire data gathered from classroom teachers in the eight schools in Year 1 (n = 66) and Year 3 (n = 62) of implementation, and semi-structured interviews with randomly selected teachers in each school in Year 4 (n = 18). In general, teachers succeeded in implementing a writing workshop approach to teaching writing, within the broader W2R literacy framework, including the allocation of more time to writing instruction. Professional development, including observation, feedback and demonstration by W2R literacy coaches, contributed to high levels of teacher confidence in such areas as planning and teaching fiction and non-fiction writing genres, and analysing writing samples to inform mini-lessons. By Year 3, teachers noted marked or good improvements in students’ attitudes towards writing, volume of writing produced, knowledge of writing genres, and language of response to writing. Areas in need of further support included aspects of the craft of writing, including writing vocabulary, supporting pupils to set goals for writing, selecting mentor texts to teach writing genres, and using a rubric to assess writing development.
Facts and Rules: Incidence of the Social Environment in the Understanding and Elaboration of Law, from the Communicational Theory of Law
Authors: Sánchez Hidalgo Adolfo J. 
Published: February 2024

Abstract
The Communicational Theory of Law (CTL) usually differentiates between Legal Sociology and Legal Theory, in the sense that Legal Sociology is concerned with the social validity of the rules and Legal Theory with the formal or legal validity of the rules. It can be argued that both disciplines are two different perspectives of the same empirical reality (legal rules). Also, legal System and social milieu are two closely linked realities; they cannot be separated because they need each other. The Law is the form or order that the social milieu takes, and, at the same time, the social environment provides the ideas, collective representations and other matters that need a legal regulation. For this reason, the epistemological separation between Sociology and Legal Theory must be overcome when the theoretical perspective comes to legal decisions. Thus, the decisional moment becomes the meeting point between the legal System and the social milieu. This is where the concept of the legal System fulfils its main function, as it allows for the dynamism and adaptability of the legal order. The hermeneutic re-elaboration of the normative texts will be the channel through which the social facts and other material elements can inform the meaning or possible interpretations of the rules and institutions of the legal order. This happens primarily by influencing theoretical and doctrinal works of an expository and didactic nature; and secondarily by influencing the decisions of legal operators and courts. This study seeks to explain how the social context influences legal decisions and the formation of the legal System, from a communicational perspective of Law. In order to do so, it will be necessary to set out two epistemological premises of CTL: the semiotic tripartition of the Theory of Law and the legal Order-legal System distinction.
Effect of carbohydrates on the adhesion of Bordetella bronchiseptica to the respiratory epithelium in rabbits
Authors: Patiño Pilar , Gallego Carolina , Martínez Nhora , Iregui Carlos , Rey Alba 
Published: February 2024

AbstractThis study proposes an ecological approach for preventing respiratory tract infections caused by Bordetella bronchiseptica in mammals using a mixture of carbohydrates. In an in vivo study, 51-day-old New Zealand rabbits were treated with a solution containing 1 × 107 CFUs of B. bronchiseptica and 250 μg of one of the following carbohydrates: N acetylglucosamine (GlcNAc), N acetylgalactosamine (GalNAc), alpha methyl mannose (AmeMan), alpha methyl glucose (AmeGlc) and sialic acid (Neu5AC). Positive (B. bronchiseptica) and negative (Physiological Saline Solution (PSS)) controls were included. Animals treated with GlcNAc or AmeGlc showed no clinical signs of infection and exhibited a significant reduction (p < 0.05) in the severity of microscopic lesions evaluated in the nasal cavity and lung compared with the positive controls. Additionally, the presence of bacteria was not detected through microbiological isolation or PCR in the lungs of animals treated with these sugars. Use of a mixture of GlcNAc and AmeGlc resulted in greater inhibition of microscopic lesions, with a significant reduction (p < 0.05) in the severity of these lesions compared to the results obtained using individual sugars. Furthermore, the bacterium was not detected through microbiological isolation, Polymerase Chain Reaction (PCR) or indirect immunoperoxidase (IIP) in this group.
Description of a new quantitative method to assess mitochondrial distribution pattern in mature equine oocytes
Authors: Luis-Calero Marcos , Fernández-Hernández Pablo , Ortiz-Rodríguez José Manuel , Muñoz-García Carmen Cristina , Jardin Isaac , Macías-García Beatriz , González-Fernández Lauro 
Published: February 2024

AbstractThe Mitochondrial distribution pattern or MDP in mammalian oocytes serves as an indicator of their cytoplasmic maturity, with a heterogeneous pattern associated with mature cytoplasm. Currently, MDP assessment involves fluorescent labelling of mitochondria followed by visual evaluation, as no quantitative method exists. Our objective was to develop a quantitative approach to assess MDP in mature equine oocytes. Equine oocytes, obtained by ovum pick up (OPU) were matured in vitro, and only metaphase II oocytes were used in the study (n = 56). Following denudation, oocytes were fixed, stained with MitoTracker™ Red CMXRos (50 nM in TCM-199 with Hank´s salts and 10% FBS) for 15 min at 38 °C, and then incubated with 2.5 µg/ml Hoechst 33342 for 10 min at 38 °C. Confocal microscope images were acquired, and the oocyte’s MDP was visually classified as either homogeneous (HoD; n = 17) or heterogeneous (HeD; n = 39). For quantitative analysis, Fiji-ImageJ software was employed. Background subtraction was performed, and a 1-pixel line along the diameter was drawn to calculate the intensity profile. Fluorescence intensities were normalized, and ratios of peripheral to central fluorescence intensity were determined. Student´s t-test was used for comparations; MDP ratio was (mean ± standard error of the mean): 0.8 ± 0.02 for HoD and 0.3 ± 0.02 for HeD (p < 0.001). These results demonstrate concordance between quantitative and qualitative MDP assessment in mature equine oocytes. Our study describes a new approach to quantify mitochondrial distribution pattern and cytoplasmic maturation in mature equine oocytes.
Differential accumulation of metals in the lacustrine and fluvial Alpine bullheads (Cottus poecilopus) and recovery of fish from metal contamination after a flash flood
Authors: Janiga Marián , Janiga Martin , Pitoňáková Tatiana 
Published: February 2024

AbstractThe spatiotemporal distribution and transport of mercury, zinc, molybdenum, rubidium, and strontium from alpine terrestrial ecosystems to alpine lake and mountain stream populations of Cottus poecilopus were investigated. Metals were measured for 66 wild fish collected from different lakes and Javorinka stream across. Mercury was measured in the pectoral fins, other elements in the skull. Bullheads contained more metals in the alpine lakes than in the mountain stream. In particular, mercury and zinc concentrations in lake bullheads were 6 and 2.5 times higher, respectively, than those of stream-dwelling fish. New data were generated on metal bioaccumulation in fish of understudied West Carpathian alpine lake environments. In July 2018, a major flood occurred in the area of the Javorinka. Already then, the mercury content in bullheads increased significantly. Bioaccumulation of mercury in fish occurred very quickly after the flood and was also significant in the following 2019. Then, the concentrations of mercury quickly decreased up to 70% in 2021–2022. Average concentrations of molybdenum and rubidium in bullheads in the stream rapidly declined in the year following the flood disturbance, but within less than 2 years, the metal levels stabilized at about the same level as in 2017 prior the flood. Strontium concentrations in fish dropped rapidly immediately after the flood, increased in the following years, and dropped again after 4 years, suggesting that many more factors are influencing strontium bioaccumulation in fish that are comparable in magnitude to the flood. The most serious warning seems to be the absence of biogenic zinc. The average concentration in the Alpine bullheads population in the stream has declined by 70% in less than 5 years and is steadily declining. An important result of this study is the demonstration that disturbance by a single factor (heavy rainfall and flooding) has a clear and timely effect on average metal concentrations in the fish population.
Graphical abstract
Arthroscopic surgery for scaphoid nonunion: a 10-year systematic literature review
Authors: Rinaldi Alberto , Pilla Federico , Chiaramonte Ilaria , Pederiva Davide , Vita Fabio , Schilardi Francesco , Gennaro Andrea , Faldini Cesare 
Published: February 2024

AbstractThe purpose of the study was to investigate whether arthroscopic treatment of carpal scaphoid nonunions by osteosynthesis with bone grafting represents a successful surgical technique. This systematic literature review, conducted following the PRISMA guidelines, explores the past 10 years of clinical studies concerning the arthroscopic treatment of scaphoid nonunions. The most relevant keywords were used to search the databases, and the Downs and Black 27-item checklist has been used as quality assessment tool. Twelve papers that meet the premised eligibility criteria have been identified. These studies demonstrate the efficacy of this surgical solution, achieving a postoperative union rate of 96% in the average time of 13.5 weeks. Regardless of the method of synthesis and the origin of the graft used, excellent results were obtained. Patients who underwent this procedure reported a pain reduction of almost 80% compared to the preoperative level, improvement in grip strength close to 40%, and recovery in wrist function during daily activities. Arthroscopy has numerous advantages compared to the open approach. These are technically recognized by the surgeon and by the patient. Some disadvantages include a longer intraoperative time and considerable significant technical difficulty. Arthroscopic treatment of scaphoid nonunion by osteosynthesis with bone graft achieves a 96% union rate of the treated scaphoid with satisfying clinical results.
Marine resource exploitation and human settlement patterns during the Neolithic in SW Europe: stable oxygen isotope analyses (δ18O) on Phorcus lineatus (da Costa, 1778) from Campo de Hockey (San Fernando, Cádiz, Spain)
Authors: García-Escárzaga Asier , Cantillo-Duarte Juan J. , Milano Stefania , Arniz-Mateos Rosa , Gutiérrez-Zugasti Igor , González-Ortegón Enrique , Corona-Borrego Jose M. , Ramos-Muñoz José , Colonese André C. , Vijande-Vila Eduardo 
Published: February 2024

AbstractIn recent decades, investigations in the southern Iberian Peninsula have increased our understanding of the socio-economic impact of the spread of the Neolithic in southwestern Europe, including changes in marine resources exploitation. Nevertheless, considerable uncertainty still exists around the seasonality of such subsistence systems and the putative role of marine fish and shellfish to the evolving agro-pastoral economies. Earlier studies on the European Atlantic coast (including Iberia) have shown that the stable oxygen isotope (δ18O) values from the topshellPhorcus lineatus(da Costa, 1778) can be reliably used to derive seasonal sea surface temperatures (SST) during its lifespan. This information can be used by archaeologists to estimate the seasonality of mollusc collection in the past, and to shed light into settlement and subsistence patterns. This paper presents the results of a stable isotope study on archaeological shells ofP. lineatusrecovered from the Neolithic settlement of Campo de Hockey (Cádiz, Spain). We analysed shells from both funerary and residential contexts and found thatP. lineatuswas consumed year-round, but with a stronger preference during winter. Our results therefore contribute to advance our understanding of the role of coastal environments in early farming societies of southwestern Europe.
A Combined Manual Annotation and Deep-Learning Natural Language Processing Study on Accurate Entity Extraction in Hereditary Disease Related Biomedical Literature
Authors: Huang Dao-Ling , Zeng Quanlei , Xiong Yun , Liu Shuixia , Pang Chaoqun , Xia Menglei , Fang Ting , Ma Yanli , Qiang Cuicui , Zhang Yi , Zhang Yu , Li Hong , Yuan Yuying 
Published: February 2024

AbstractWe report a combined manual annotation and deep-learning natural language processing study to make accurate entity extraction in hereditary disease related biomedical literature. A total of 400 full articles were manually annotated based on published guidelines by experienced genetic interpreters at Beijing Genomics Institute (BGI). The performance of our manual annotations was assessed by comparing our re-annotated results with those publicly available. The overall Jaccard index was calculated to be 0.866 for the four entity types—gene, variant, disease and species. Both a BERT-based large name entity recognition (NER) model and a DistilBERT-based simplified NER model were trained, validated and tested, respectively. Due to the limited manually annotated corpus, Such NER models were fine-tuned with two phases. The F1-scores of BERT-based NER for gene, variant, disease and species are 97.28%, 93.52%, 92.54% and 95.76%, respectively, while those of DistilBERT-based NER are 95.14%, 86.26%, 91.37% and 89.92%, respectively. Most importantly, the entity type of variant has been extracted by a large language model for the first time and a comparable F1-score with the state-of-the-art variant extraction model tmVar has been achieved.
Graphical Abstract
Antibiotic resistance and tolerance: What can drug delivery do against this global threat?
Authors: Aparicio-Blanco Juan , Vishwakarma Nikhar , Lehr Claus-Michael , Prestidge Clive A. , Thomas Nicky , Roberts Richard J. , Thorn Chelsea R. , Melero Ana 
Published: February 2024

AbstractAntimicrobial resistance and tolerance (AMR&T) are urgent global health concerns, with alarmingly increasing numbers of antimicrobial drugs failing and a corresponding rise in related deaths. Several reasons for this situation can be cited, such as the misuse of traditional antibiotics, the massive use of sanitizing measures, and the overuse of antibiotics in agriculture, fisheries, and cattle. AMR&T management requires a multifaceted approach involving various strategies at different levels, such as increasing the patient’s awareness of the situation and measures to reduce new resistances, reduction of current misuse or abuse, and improvement of selectivity of treatments. Also, the identification of new antibiotics, including small molecules and more complex approaches, is a key factor. Among these, novel DNA- or RNA-based approaches, the use of phages, or CRISPR technologies are some potent strategies under development. In this perspective article, emerging and experienced leaders in drug delivery discuss the most important biological barriers for drugs to reach infectious bacteria (bacterial bioavailability). They explore how overcoming these barriers is crucial for producing the desired effects and discuss the ways in which drug delivery systems can facilitate this process.
Graphical abstract
Fabrication of a Nanomagnetic Smart Polymer Carrier as a Potential Candidate for a Drug Delivery System
Authors: Jafarzadeh Fereshteh , Peyman Hossein , Roshanfekr Hamideh , Azizi Shohreh , Idris Azeez Olayiwola , Maaza Malik 
Published: February 2024

AbstractWe developed an intelligent device capable of controlled release of anti-cancer drugs. The nano-carrier consists of two key components: firstly, magnetic nanoparticles were synthesized through co-precipitation and then functionalized for attaching anti-cancer drugs; secondly, a polymer (poly(N-isopropylacrylamide-co-acrylic acid)) sensitive to pH and temperature was synthesized and employed to encapsulate the drug-loaded magnetic nanoparticles. This responsive polymer exhibits a lower critical solution temperature (LCST) of 38.5 °C, indicating a phase transition behavior. Numerous techniques and analyses, including Fourier transform infrared spectroscopy, thermogravimetric analysis, zeta potentials, scanning electron microscope, and transmission electron microscopy, were employed to confirm the successful execution of the aforementioned process. In vitro release assessments of the anti-cancer drug, doxorubicin, were conducted across various media (pH 5–8 and temperatures ranging from 20 to 40 °C). The outcomes revealed higher drug releases at temperatures exceeding the LCST (40 °C) and at slightly acidic pH levels (5–5.3). Notably, compared to the effectiveness of the unloaded drug, the magnetic smart polymer loaded with DOX exhibited a more potent cytotoxic effect. Considering these results, this nano-carrier emerges as a promising candidate for targeted therapeutic delivery to cancerous tissues.
Intelligent learning-based cooperative and competitive multi-objective optimization for energy-aware distributed heterogeneous welding shop scheduling
Authors: Zhang Fayong , Li Caixian , Li Rui , Gong Wenyin 
Published: February 2024

AbstractThis research is focused on addressing the energy-aware distributed heterogeneous welding shop scheduling (EADHWS) problem. Our primary objectives are to minimize the maximum finish time and total energy consumption. To accomplish this, we introduce a learning-based cooperative and competitive multi-objective optimization method, which we refer to as LCCMO. We begin by presenting a multi-rule cooperative initialization approach to create a population that combines strong convergence and diversity. This diverse population forms the foundation for our optimization process. Next, we develop a multi-level cooperative global search strategy that explores effective genes within solutions from different angles and sub-problems. This approach enhances our search for optimal solutions. Moreover, we design a competition and cooperation strategy for different populations to expedite convergence. This strategy encourages the exchange of information and ideas among diverse populations, thereby accelerating our progress. We also introduce a multi-operator cooperative local search technique, which investigates elite solutions from various directions, leading to improved convergence and diversity. In addition, we integrate Q-learning into our competitive swarm optimizer to explore different regions of the objective space, enhancing the diversity of the elite archive. Q-learning guides the selection of operators within the small-size population, contributing to more efficient optimization. To evaluate the effectiveness of LCCMO, we conduct numerical experiments on 20 instances. The experimental results unequivocally demonstrate that LCCMO outperforms six state-of-the-art algorithms. This underscores the potential of our learning and knowledge-driven evolutionary framework in enhancing performance and autonomy when it comes to solving EADHWS.
Team formation through an assessor: choosing MARL agents in pursuit–evasion games
Authors: Zhao Yue , Ju Lushan , Hernández-Orallo Josè 
Published: February 2024

AbstractTeam formation in multi-agent systems usually assumes the capabilities of each team member are known, and the best formation can be derived from that information. As AI agents become more sophisticated, this characterisation is becoming more elusive and less predictive about the performance of a team in cooperative or competitive situations. In this paper, we introduce a general and flexible way of anticipating the outcome of a game for any lineups (the agents, sociality regimes and any other hyperparameters for the team). To this purpose, we simply train an assessor using an appropriate team representation and standard machine learning techniques. We illustrate how we can interrogate the assessor to find the best formations in a pursuit–evasion game for several scenarios: offline team formation, where teams have to be decided before the game and not changed afterwards, and online team formation, where teams can see the lineups of the other teams and can be changed at any time.