bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphometric and Hypsometric Analyses in Prioritizing Sub‑watersheds of Drought-prone Barind Tract, NW Bangladesh: Statistical and Geospatial Tools for Soil Conservation Study
Authors: Ghose Bakul Kumar , Hassan Md. Nahid , Islam Monirul , Howlader Rakib , Rahman Md. Redwanur , Mazumdar Quamrul Hasan , Jahan Chowdhury Sarwar 
Published: December 2023

Abstract
Approach of watershed management activities have eventual role in soil conservation and protection of land degradation by adopting improved and refined efficient tool based on sub-watershed (SW) prioritization which is considered as effective initiatives for their sustainability. Present study has aimed to identify SWs in the topographically elevated drought–prone Barind Tract in NW Bangladesh from where runoff water flows to the surrounding perennial river basins making the areas vulnerable to soil erosion and land degradation. Here, the management approach by morphometric and hypsometric analyses have taken to assess the impact of geomorphological processes on SWs hydrology with the help of geomorphic information system (GIS) and remote sensing (RS) tools with statistical and geospatial technique for prioritizing SW. The analysis of morphometric parameters indicates that the sub-watersheds (SW2, SW11 and SW13) have high susceptibility to soil erosion. On the other hand, the hypsometric analysis shows that SWs (except WS13) are prioritized as high grade. The correlation matrix of 18 (eighteen) geomorphic parameters of studied SWs indicates possible interrelationship between multiple parameters in order to obtain the first factor rotated loading matrix. The sub-watersheds (SW2 and SW11) are categories as high priority class using the Principal Component Analysis (PCA) and the Weight Sum Approach (WSA), and reveals that they are more susceptible to land degradation than that of others. The high rates of soil erosion and land degradation result serious environmental hazard in ecosystem, and create economic hardship. Finally, it may be reveal that findings of present study will be remarkably important for stakeholder to enable decision-making process for strategies in watershed development and management initiatives through ecosystem-based adaptation (EbA) for soil and water conservation in the country.
Inhibitory effects of cenobamate on multiple human cardiac ion channels and possible arrhythmogenic consequences
Authors: Amuzescu Bogdan , Corlan Alexandru Dan , Radu Beatrice Mihaela 
Published: December 2023

Abstract
Cenobamate is a novel third-generation antiepileptic drug used for treatment of focal onset seizures and particularly for multi-drug-resistant epilepsy, producing a reduction in monthly seizure frequency of up to 55% and unprecedented seizure-free rates of up to 28% due to action on multiple targets: GABAA receptors (EC50 42–194µM) and inhibition of persistent neuronal Na+ currents (IC50 59µM). Side effects include QTc interval shortening with > 20ms, but not < 300ms; therefore, cenobamate is forbidden for patients with short QT syndrome. Our in vitro cardiac safety pharmacology study was performed via whole-cell patch-clamp on HEK293T cells with persistent/inducible expression of human cardiac ion channel isoforms hNav1.5 (INa), hCav1.2 (α1c + β2 + α2δ1) (ICaL), hKv7.1 + mink (IKs), and hKv11.1 (hERG) (IKr), using specific bath/pipette solutions and voltage protocols. Thus, we succeeded to evidence for exposure to cenobamate 200µM average inhibitions (± SD) of 69.5 ± 14.6% for peak INa, 39.3 ± 13.8% for peak ICaL (which may explain QT shortening effects), 36.7 ± 13.0% vs. 23.7 ± 9.9% in control experiments for IKs, 5.3 ± 1.8% vs. 4.1% in control experiments for IKr (at 20µM). The marked inhibition by cenobamate of INa raises the theoretical possibility of cardiac arrhythmia induction at therapeutic concentrations in the context of preexisting myocardial pathology, in the presence of electrophysiological conduction and repolarization heterogeneity. This hypothetical mechanism is consistent with known effects of class Ib antiarrhythmics. In preliminary simulations with linear cardiomyocyte strands we found a negligible cenobamate-induced conduction delay in normal tissue, but a marked delay and also block when gap junction conduction was already depressed.
Do cucumbers sleep during Witching hour?
Authors: Takagi Osamu , Sakamoto Masamichi , Kawano Kimiko , Yamamoto Mikio 
Published: December 2023

Abstract
In recent years, several lines of evidence have been reported indicating that brainless organisms also sleep. In this paper, with the aim of answering the question of whether brainless plants also sleep, we analyzed the relationship between the diurnal time at which cucumber sections were prepared and the concentration of gas released from the sections within a certain period of time thereafter. The results showed that the gas concentration released from cucumber sections prepared around 2:00 a.m., the middle of the night, known in Japan as "Ushi-Mitsu-Doki", was the lowest of the day. Our results suggested that the gas production reaction of cucumbers changes depending on the time of sectioning, and that cucumbers were in a state resembling sleep at the "Ushi-Mitsu-Doki" time.
Temporal changes in survival among adult patients with acute lymphoblastic leukemia diagnosed in the period 1998-2020 – A Danish nationwide population-based study
Authors: Kristensen Daniel Tuyet , Jåtun Trine Louise , Simonsen Mikkel Runason , Toft Nina , Dimitrijevic Andreja , Ørskov Andreas , Roug Anne , El_Galaly Tarec , Severinsen Marianne 
Published: December 2023

Abstract
Previous studies have shown continuous improved overall survival (OS) for adults with acute lymphoblastic leukemia (ALL) up to 2015. However, since 2015 several important advances have been made justifying a more contemporary analysis of outcomes in adult ALL. Here we quantify progress in OS for adult Danish patients with ALL diagnosed between 1998 and 2020 using flexible parametric survival models. This population-based study includes 657 patients and demonstrates a significant improvement in OS over time with the 2-year age standardized OS increasing from 36.2% (95% CI, 26.8–45.6%) in 1998 to 68.5% (95% CI, 60.1–76.9) in 2020, corresponding to an absolute increase in 2-year OS of 32.3 percent points (95% CI, 19.3–45.4) during the surveyed period. Stratified analysis revealed improvements for both Philadelphia chromosome positive and negative ALL, across cytogenetic risk classes, and for B- and T-cell ALL, whereas the latter did not reach statistical significance. Additionally, in age strata improvements were seen across all ages; however, most pronounced for the younger patients ≤ 60 years. These results indicate a universal and continuous improvement in the treatment of adult ALL. Currently, novel treatment combination and advances in cellular therapy occur rapidly, and we expect even further improvements in the years to come.
Association of indications for mandibular third molar coronectomy and the Pell and Gregory and the Winter classification systems
Authors: Simons Rashida N. , Gonesh Mitchell S. , Tuk Jacco G. , de Lange Jan , Lindeboom Jerome A.H. 
Published: December 2023

Abstract
Purpose: The purpose of this study was to determine how the surgeon’s decision to perform a mandibular third molar coronectomy or surgical removal is associated with the impaction pattern as classified using Pell and Gregory or Winter’s system.
Methods: This observational, cross-sectional study was conducted on 813 mandibular third molars belonging to 565 patients. All patients were referred for removal of the mandibular third molar and had radiographic signs indicating a close relationship with the inferior alveolar nerve. Panoramic images were classified according to the impaction pattern.
Results: A coronectomy was performed on 492 (60.5%) mandibular third molars.
Most impacted mandibular third molars were class IIB with a mesioangular inclination. A significant association was found between the Pell and Gregory classification and the surgeon’s choice (p = 0.002). Winter’s classification was not significantly associated with surgeon choice (p = 0.425).
Conclusion: Mandibular third molar coronectomy is chosen more frequently than surgical removal if molars are class III and position B.
Development of the Perineal Health Behavior Scale: Data from Rural Women in Huaning County, Yunnan Province, China
Authors: Feng Lin-Sen , Meng Yang-xuan , Guo Wen-ran , Shen Ya , Zhang Yi-yan , Yan Ruo-yu , Wang Hao-yu , Song Yi-xiao , Xie Jia-qi , Dong Zheng-jiao 
Published: December 2023

Abstract
Purpose
To develop a set of Perineal Health Behavior Scale (PHBS) for adult female, and verify the reliability and validity of the scale.
Methods
The PHBS was developed using classical measures. The draft version of PHBS was compiled by semi-structured interview method (N = 8), Delphi expert consultation method (N = 5), and cognitive interviewing techniques (N = 20). A total of 1397 rural women from Huaning County were selected to participate in the survey. After items screening, the reliability and validity of final version of PHBS were verified. The influencing factors of perineal health behavior were explored by Multiple linear regression analysis.
Results
There were 11 items in the PHBS, including two dimensions – daily life (7 items), and sexual life (4 items). The scale had good structural validity, convergent validity, discriminant validity, content validity, internal consistency reliability, and split-half reliability. Multiple linear regression showed that suburban rural areas, higher education, and good family relationships were protective factors for poor perineal hygiene behavior (P < 0.05); High social pressure, irregular menstrual cycle, normal/less menstrual volume, and self-reported current genital tract infection are risk factors for poor perineal hygiene behavior (P < 0.05).
Conclusions
The PHBS was a reliable and valid measure to evaluate the level of perineal health behavior in adult female. In the work of health education and health promotion, we should focus on improving the perineal hygiene behaviors and habits of adult female in rural communities (especially remote rural communities).
Integrated Modeling for In-Depth EEG Based Emotional State Analysis via Convolutional-Transformer Fusion
Authors: Ali Noman , Kang A. S , Himral Saurabh 
Published: December 2023

Abstract

This study introduces a hybrid model designed for the predic- tion of emotional states derived from electroencephalogram (EEG) data, employing an amalgamation of convolutional and trans- former layers. The architectural framework of the model is metic- ulously structured to facilitate concurrent assimilation of local pat- terns and long-range dependencies inherent in EEG data, thereby augmenting its discernment of nuanced emotional experiences. The investigation presented herein undertakes a comprehensive explo- ration of the fusion technique, with a primary focus on dis- cerning three elemental emotional dimensions: Arousal, Valence, and Dominance, in addition to their concurrent combinations. The research methodology encompasses an in-depth evaluation of the model’s performance across these diverse emotional states, encompassing the intricate task of simultaneous Valence-Arousal (VA) prediction. Furthermore, the study extends its purview to encompass the intricate Valence-Arousal-Dominance (VAD) space, thereby providing a thorough analysis of the model’s efficacy. To articulate the model’s discriminative efficacy, this study meticu- lously presents the detailed F1 scores corresponding to each emotional state classification: Arousal (96.8), Valence (97.3), Valence-Arousal (VA) simultaneously (95.6), and Valence-Arousal-Dominance simultaneously (94.9). These scores serve as a testament to the model’s robust per- formance across diverse emotional dimensions. Importantly, to fortify the credibility of our findings, rigorous experimentation has been con- ducted on the DEAP dataset, unveiling noteworthy results even in scenarios involving simultaneous recognition of multiple emotional states.
Land-Use Change, No-Net-Loss Policies, and Effects on Carbon Dioxide Removals
Authors: Wear David N. , Wibbenmeyer Matthew 
Published: December 2023

Abstract

Background
Carbon dioxide removal from the atmosphere (CDR) is a critical component of strategies for restricting global warming to 1.5oC and is expected to come largely from the sequestration of carbon in vegetation. Because CDR rates have been declining in the United States, in part due to land use changes, policy proposals are focused on altering land uses, through afforestation, avoided deforestation, and no-net-loss strategies. Estimating policy effects requires a careful assessment of how land uses interact with forest conditions to determine future CDR.
Results
We evaluate how alternative specifications of land use-forest condition interactions in the United States affect projections of CDR using a model that mirrors land sector net emission inventories generated by the US government (EPA). Without land use change, CDR declines from 0.826 GT/yr in 2017 to 0.596 GT/yr in 2062 (28%) due to forest aging and disturbances. For a land use scenario that extends recent rates of change, we compare CDR estimated based on net changes in land use (Net Change model) and estimates that separately account for the distinct CDR implications of forest losses and forest gains (Component Change model). The Net Change model, a common specification, underestimates the CDR losses of land use by about 56 percent when compared with the Component Change models. We also estimate per hectare CDR losses from deforestation and gains from afforestation and find that afforestation gains lag deforestation losses in every ecological province in the US.
Conclusions
Net Change approaches substantially underestimate the impact of land use change on CDR and should be avoided. Component Change models highlight that avoided deforestation may provide up to twice the CDR benefits as increased afforestation—though preference for one policy over the other would require a cost assessment. The disparities in the CDR impacts of afforestation and deforestation indicate that no-net-loss policies could mitigate some CDR losses but would lead to overall declines in CDR for our 45-year time horizon. Over a much longer period afforestation could capture more of the losses from deforestation but at a timeframe inconsistent with most climate change policy efforts.
The modal damping ratio of a Single-Degree-of-Freedom (SDOF)
Authors: Felahi Saci 
Published: December 2023

Abstract
Both NeXT and RDT techniques have their advantages and limitations, and the choice between them depends on the specific requirements and characteristics of the structural system being analyzed. It's recommended to consult relevant literature or seek guidance from experts to ensure accurate and reliable computation of the free-decay response from ambient vibrations.
An iron isotopic perspective for the material flow from off-axis mantle plume to mid-ocean ridge system
Authors: Zhang Haitao , Yan Quanshu , Li Chuanshun , Shi Xuefa , Huang Fang , Shen Fangyu , Wen Qiuyu , Wang Ruirui 
Published: December 2023

Abstract
The interaction between the mid-oceanic ridge (MOR) and the mantle plume is a crucial aspect for understanding Earth’s internal works. However, the compositions and styles of material flow from off-axis plumes to the MOR system still remains elusive. This study examined the iron (Fe) isotope composition of basalts from the South Mid-Atlantic Ridge (SMAR) for the first time. The results showed a consistent relationship between the Fe isotope compositions, trace element ratios, and traditional radiogenic isotopic compositions of lavas from the SMAR and the off-axis Saint Helena plume. This suggests that variations in the Fe isotope compositions of the SMAR mantle source may be influenced by the contribution of the Saint Helena plume. We propose that heavy-Fe pyroxenites are widely distributed within the lithosphere-asthenosphere boundary (LAB) layer in the region between the plume and ridge. These plume-related pyroxenites can transport plume signatures with heavy Fe isotopic compositions into the MOR system at the LAB level.
Optimizing Nanofluid Formulations for Enhanced Thermophysical Properties in Crude Oil: A Study of MWCNTs and SDS in EOR Processes
Authors: Mousavi Seyed Borhan 
Published: December 2023

Abstract
This research delved into the effects of introducing multi-walled carbon nanotubes (MWCNTs) and sodium dodecyl sulfate (SDS) into crude oil with an anionic base, aiming to enhance its thermophysical attributes in the EOR process. The investigation encompassed a range of properties, including interfacial tension, viscosity, density, and electrical conductivity, measured using an LV rheometer with spindle 18. Various ratios of MWCNTs and SDS were mixed with the crude oil to evaluate their impacts. The study uncovered that the 1:1 ratio of MWCNTs to SDS achieved a noteworthy 10% reduction in interfacial tension while minimally affecting viscosity, showing promise for practical applications. Temperature had diverse effects on viscosity and interfacial tension, displaying fluctuating trends. The highest observed result was a substantial 190% viscosity increase at 40°C with a 2:1 ratio, whereas the lowest was a slight − 0.81% density change at 60°C for the 1:1 ratio. Additionally, interfacial tension consistently decreased over time for all ratios at various temperatures, with the most significant reductions observed at 40°C and 60°C, particularly for the 1:2 and 1:1 ratios. Furthermore, adding MWCNTs and SDS led to a remarkable drop in electrical conductivity, indicating a substantial decrease in salt content within the crude oil. However, it was noted that higher MWCNT concentrations might not be cost-effective, emphasizing the importance of optimizing additive ratios for a balance between performance and economic viability. This study highlights the potential of tailored nanofluid formulations to improve the thermophysical properties of crude oil, potentially enhancing extraction and refining processes.
Surgical management of carpal tunnel syndrome
Authors: nattouf Farouk , Barakat Ahmad , Abdin Jihad 
Published: December 2023

Abstract

Background and Aim:
To determine the prevalence and risk factors of carpal tunnel syndrome among patients who visited Damascus Hospital between the years 1/1/2015 and 1/1/2023 and their relationship with age, gender, and clinical symptoms.
Methods and material:
Information was collected according to the research form to adjust the inclusion and exclusion criteria, and the clinical history information was recorded in detail, which included: age, sex, habits, Tinel's sign, Phalen's maneuver, whether diabetes was present, and other symptoms and signs. The study included 80 male and female patients.
Results:
Most of the patients are in the age group of 25–45 years (57.5%), and the percentage of infected females constituted about two-thirds of the patients (62.5%), and a third of the patients were smokers (30%), and a quarter of the patients had diabetes, and the percentage of pregnant women was (11.3). A statistically significant relationship between gender and signs and symptoms (positive Tinel's sign, positive Phalen's maneuver, presence of numbness, presence of tingling, loss of sensation, presence of pain, presence of weakness and muscle atrophy, presence of complex regional pain, presence of tenderness of scars) (statistical significance less than 0.05), There is a statistically significant relationship between all symptoms and signs except complex regional pain syndrome and scar tenderness, and there is a statistically significant relationship between both diabetes and (positivity of Tinel's sign, positivity of Phalen's maneuver, presence of numbness, presence of tingling, loss of sensation, presence of pain), absence of a relationship. There is a statistically significant relationship between smoking and the occurrence of signs and symptoms, and there is a statistically significant relationship between pregnancy and (positivity of Tinel's sign, positivity of Phalen's maneuver, presence of numbness, presence of tingling).
conclusion:
A health care professional can diagnose patients with mild symptoms of carpal tunnel syndrome without the need for additional testing, and patients with unusual or severe symptoms should undergo electrodiagnostic tests.
Paradigmas do planejamento territorial e as novas faces do rural: Óticas urbanocêntricas em tempos de complementaridade
Authors: Bariviera Cássio Alexandre , Oliveira Daniela 
Published: December 2023

Dadas as mudanças paradigmáticas ocorridas na trajetória do planejamento no Brasil, principalmente no período pós Constituição Federal de 1988 e Estatuto da Cidade, Lei Federal 10.257 de 2001, assim como a emergência de estudos do desenvolvimento rural que versam sobre novos fenômenos e arranjos neste meio, o objetivo desta pesquisa é investigar como o rural tem sido tratado pelos instrumentos de planejamento territorial dos 32 municípios do Corede Norte do estado do Rio Grande do Sul. Para isto, fez-se uso de uma revisão bibliográfica, seguida de uma pesquisa documental direcionada aos instrumentos de planejamento dos 32 municípios. Como resultado, observou-se a predominância de instrumentos básicos da política urbana enquanto principais instrumentos de planejamento territorial existentes, instrumentos esses que ainda perpetuam noções exclusivamente urbanas para o planejamento e exclusivamente agrícolas para o rural. Nos casos onde o rural foi incluído pelos instrumentos analisados, estes seguem atrelando-o a ótica de oposição à cidade e atribuindo-lhe a destinação agro-silvo-pastoril. Em suma, observou-se uma região marcada por ricas relações entre áreas rurais e urbanas, todavia, ainda carente de instrumentos de planejamento territorial que façam jus à complementaridade entre áreas urbanas e rurais.
Permeable pavement hydraulic optimization by using an analytical-probabilistic model
Authors: Marchioni Mariana , Raimondi Anita , Di Chiano Maria Gloria , Becciu Gianfranco 
Published: December 2023

Abstract
On-source storage controls are a sustainable solution for stormwater management in a scenario of continuous urban area growth. Structures that manage storage volumes through infiltration include extra environmental benefits, such as groundwater recharge, evapotranspiration, and pollutant load removal. Permeable pavement systems are among these controls and can easily integrate into dense urban areas, resulting in paved surfaces contributing to stormwater management. The shift toward on-source strategies is encouraged through regulations, policies, incentives, and awareness campaigns, which are substantially increasing their dissemination. Optimizing the design of on-source storage controls with infiltration, such as permeable pavement systems, through robust methodologies can reduce reservoir depth, reducing environmental impact and costs without impact on reliability. The analytical-probabilistic (AP) method using derived probability distribution theory from rainfall event characteristics and the mathematical description of hydrologic processes within the permeable pavement systems provides an analytical equation that can be used as a design tool, proving robustness analogous with continuous simulations. Results obtained with the AP method were compared with traditional event-based methodologies and continuous simulation, assessing the reliability of the proposed method in optimizing permeable pavement systems' reservoir depth.