bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring social influence effect on mobile marketing behaviors of young consumers in the USA and Mexico
Authors: Oyedele Adesegun , Goenner Emily 
Published: November 2023

Purpose
This study aims to investigate the effect of social influence and value-driven mobile marketing activities on consumers’ acceptance of mobile marketing offers.

Design/methodology/approach
The method used is survey questionnaire. A proposed model was tested by using structural model analysis and data gathered from 356 Mexico consumers and 346 US consumers.

Findings
The study shows the number of peers and providing information are the main predictor variables of consumer acceptance of mobile marketing offers in both countries. These results suggest that social value factors are important variables for explaining consumers’ responses to mobile marketing offers across two countries characterized by dissimilar macro-environmental conditions.

Research limitations/implications
The study’s overall implication about standardization vs adaptation is that social value messages can be standardized across countries. However, the marketing tools and touch points required to communicate any message appeal must be adapted across countries. One limitation in this study is the use of a convenience sample of undergraduate college students. This study did not control for different types of mobile phones and the screen sizes of mobile phones.

Practical implications
The overall implication of standardization vs adaptation from the study results is that social value messages can be standardized across countries. However, the marketing tools and touch points required to communicate any message appeal must be adapted across countries.

Originality/value
Unlike previous studies where the emphasis is to explicate the effect of value-oriented mobile activity, this study examines the combined effect of social influence and value-driven mobile activities on acceptance of mobile marketing.
Species–area relationships of plants and microbes are driven by different mechanisms in patchy grassland fragments
Authors: Song Yueqing , Chase Jonathan M. , Zhou Yipeng , Xu Man , Xiao Yingli , Niu Yongjie , Liu Hairong , Wang Ling 
Published: November 2023

Abstract

The island species–area relationship (SAR) describes how the number of species on an island varies with its area and provides important information about the maintenance of species diversity and how species might be lost as habitats are lost and fragmented. While the island SAR has been widely studied among macroorganisms, patterns for soil microbes have been less forthcoming, as have analyses of potential underlying mechanisms.

We examined the SAR patterns of plants, soil fungi and bacteria among remnant grassland fragments isolated by degraded habitat matrix in a steppe grassland.

As expected, we found that the total species richness of plants, fungi and bacteria in the entire fragment decreased with decreasing fragment area. However, the mechanisms differed among taxa. For plants, the lower diversity was most likely because of decreases in habitat quality and habitat heterogeneity on smaller fragments. For fungi, we found similar results, but also an important interaction with plant diversity, suggesting they were coupled via their functional associations. For bacteria, the lower diversity on smaller fragments primarily resulted from a sampling effect from the larger species pool, which outweighed the effect of higher habitat heterogeneity on smaller fragments.

Synthesis: Our study highlights that fragmentation‐induced loss of diversity can have many different underlying mechanisms and that understanding these mechanisms can provide useful insights to project future biodiversity loss and conservation.
Oral lichenoid lesions in two snuff users with contact allergy to carvone
Authors: Adwa Usamah , Antelmi Annarita , Sukakul Thanisorn , Dahlin Jakob , Bruze Magnus , Svedman Cecilia 
Published: November 2023

AbstractBackgroundContact allergy to the mint‐tasting flavour carvone has been observed in patients with oral lichenoid lesions (OLL). Mint‐flavoured products such as toothpaste frequently contain carvone. Snuff is a smokeless tobacco product that is chewed or placed in the mouth rather than smoked. In Sweden, the use of snuff and its flavoured versions is extremely common.ObjectivesTo investigate whether the consumption of mint‐flavoured snuff is associated with contact allergy to carvone and subsequently plays a role in the aetiology of OLL.MethodsRegarding the two patients, patch testing with snuff pouches was performed. High‐performance liquid chromatography and gas chromatography–mass spectrometry analysis were used for identification of carvone in different snuff samples.ResultsTwo patients with OLL were contacted allergic to carvone when patch tested. Both were using mint‐flavoured snuffs several hours a day for many years. One patient was contacted allergic to the snuff pouch tested as is. Carvone was detected in the snuff samples of both patients.ConclusionsThe patients were recommended to avoid the use of mint‐flavoured snuffs, toothpaste and foodstuffs. At follow‐up 3 months later, the patients had a dramatic clinical improvement of the OLL and oral symptoms. Exposure to mint‐flavoured snuffs can be overlooked as a possible aggravating/provoking factor in OLL.
Health state utility values for children and adolescents with type 1 diabetes: A systematic review and meta‐analysis
Authors: Xie Shitong , Li Meixuan , Chen Xin , Guo Weihua , Liu Xinran , Yang Kehu , Wu Jing 
Published: November 2023

AbstractBackgroundType 1 diabetes mellitus (T1DM) is one of the most burdensome chronic diseases in the world. Health utility values are an important tool for quantifying this disease burden and conducting cost‐utility analyses. This review aimed to derive a reference set of health utility values for children and adolescents with T1DM.MethodsWe searched MEDLINE and Embase from inception to March 2023 for health utility values of T1DM children and adolescents (aged ≤18 years) measured using direct and indirect preference elicitation approaches. Utility estimates were pooled by meta‐analyses with subgroup analyses to evaluate differences by populations and elicitation approaches.ResultsSix studies involving 1276 participants were included in this study. Meta‐analysis showed the overall utility value of children and adolescents with T1DM was 0.91 (95% CI 0.89–0.93). The utility value of T1DM children and adolescents with complications was 0.90 (95% CI 0.88–0.92), which was lower than those without complications (0.96, 95% CI 0.95–0.97). The utility value of children (aged <13 years) was higher than adolescents (aged 13–18 years) (0.90 vs. 0.85). The utility value measured by the EQ‐5D‐3L (0.91) was higher than the HUI3 (0.89), the SF‐6Dv1 (0.83), and the time trade‐off (0.81). The parent proxy‐reported was similar to the patient self‐reported (0.91 vs. 0.91).ConclusionsThis study developed a reference set of pooled utility estimates for children and adolescents with T1DM, which is helpful for understanding the overall health status of T1DM and conducting economic evaluations. Further studies are needed to explore the utilities of T1DM with different types of complications.
Testing optimal defence theory in a social insect: Increased risk is correlated with increased venom investment
Authors: Koenig Phoebe A. , Moreau Corrie S. 
Published: November 2023

Abstract
Investment in defence may not be uniformly beneficial across an organism's lifespan. Risk, and therefore potential payoff of defence, may change with age and behaviour, but for colony‐living organisms, it may also change with colony size and reproductive stage.
The acorn ant Temnothorax longispinosus uses venom to defend against socially parasitic ants that raid their nests to steal brood. We investigated the idea that T. longispinosus adjust their venom allocation in accordance with raid risk. We tested the predictions that T. longispinosus ants should produce more venom when raids are most likely to occur and during the parts of the nest reproductive cycle when the potential fitness loss per raid is highest. We also asked whether venom volume varies between nurses and foragers within a colony, which have different potential risk levels, and whether this difference increases with colony size.
We found that workers had more venom in the summer, both before and during the period when raids occur, than in the fall when pupae were no longer present in nests. Workers engaging in nursing behaviours had more venom as the pupa to worker ratio in the nest increased, indicating that nurses invest more in venom as the relative number of pupae requiring defence increases. In addition, the difference in venom volume between nurses and foragers grew with colony size.
These results provide observational support for the hypothesis that individuals vary their investment in venom over their colony's development in conjunction with the risk of social parasitism.
Loss of plasticity in maturation timing after ten years of captive spawning in a delta smelt conservation hatchery
Authors: LaCava Melanie E. F. , Griffiths Joanna S. , Ellison Luke , Carson Evan W. , Hung Tien‐Chieh , Finger Amanda J. 
Published: November 2023

AbstractAdaptation to captivity in spawning programs can lead to unintentional consequences, such as domestication that results in reduced fitness in the wild. The timing of sexual maturation has been shown to be a trait under domestication selection in fish hatcheries, which affects a fish's access to mating opportunities and aligning their offspring's development with favorable environmental conditions. Earlier maturing fish may be favored in hatchery settings where managers provide artificially optimal growing conditions, but early maturation may reduce fitness in the wild if, for example, there is a mismatch between timing of reproduction and availability of resources that support recruitment. We investigated patterns of maturation timing in a delta smelt (Hypomesus transpacificus) conservation hatchery by quantifying changes to the median age at maturity since the captive spawning program was initiated in 2008. Over the span of a decade, we observed a small, but significant increase in age at maturity among broodstock by 2.2 weeks. This trait had low heritability and was largely controlled by phenotypic plasticity that was dependent on the time of year fish were born. Fish that were born later in the year matured faster, potentially a carryover from selection favoring synchronous spawning in the wild. However, higher DI (domestication index) fish showed a loss of plasticity, we argue, as a result of hatchery practices that breed individuals past peak periods of female ripeness. Our findings suggest that the hatchery setting has relaxed selection pressures for fish to mature quickly at the end of the year and, consequently, has led to a loss of plasticity in age at maturity. Hatchery fish that are re‐introduced in the wild may not be able to align maturation with population peaks if their maturation rates are too slow with reduced plasticity, potentially resulting in lower fitness.
The neglected roles of adjacent natural ecosystems in maintaining bacterial diversity in agroecosystems
Authors: Peng Ziheng , Yang Yunfeng , Liu Yu , Bu Lianyan , Qi Jiejun , Gao Hang , Chen Shi , Pan Haibo , Chen Beibei , Liang Chunling , Li Xiaomeng , An Yining , Wang Shaopeng , Wei Gehong , Jiao Shuo 
Published: November 2023

AbstractA central aim of community ecology is to understand how local species diversity is shaped. Agricultural activities are reshaping and filtering soil biodiversity and communities; however, ecological processes that structure agricultural communities have often overlooked the role of the regional species pool, mainly owing to the lack of large datasets across several regions. Here, we conducted a soil survey of 941 plots of agricultural and adjacent natural ecosystems (e.g., forest, wetland, grassland, and desert) in 38 regions across diverse climatic and soil gradients to evaluate whether the regional species pool of soil microbes from adjacent natural ecosystems is important in shaping agricultural soil microbial diversity and completeness. Using a framework of multiscales community assembly, we revealed that the regional species pool was an important predictor of agricultural bacterial diversity and explained a unique variation that cannot be predicted by historical legacy, large‐scale environmental factors, and local community assembly processes. Moreover, the species pool effects were associated with microbial dormancy potential, where taxa with higher dormancy potential exhibited stronger species pool effects. Bacterial diversity in regions with higher agricultural intensity was more influenced by species pool effects than that in regions with low intensity, indicating that the maintenance of agricultural biodiversity in high‐intensity regions strongly depends on species present in the surrounding landscape. Models for community completeness indicated the positive effect of regional species pool, further implying the community unsaturation and increased potential in bacterial diversity of agricultural ecosystems. Overall, our study reveals the indubitable role of regional species pool from adjacent natural ecosystems in predicting bacterial diversity, which has useful implication for biodiversity management and conservation in agricultural systems.
Molecular regulation of virulence in Legionella pneumophila
Authors: Graham Christopher I. , MacMartin Teassa L. , de Kievit Teresa R. , Brassinga Ann Karen C. 
Published: November 2023

AbstractLegionella pneumophila is a gram‐negative bacteria found in natural and anthropogenic aquatic environments such as evaporative cooling towers, where it reproduces as an intracellular parasite of cohabiting protozoa. If L. pneumophila is aerosolized and inhaled by a susceptible person, bacteria may colonize their alveolar macrophages causing the opportunistic pneumonia Legionnaires' disease. L. pneumophila utilizes an elaborate regulatory network to control virulence processes such as the Dot/Icm Type IV secretion system and effector repertoire, responding to changing nutritional cues as their host becomes depleted. The bacteria subsequently differentiate to a transmissive state that can survive in the environment until a replacement host is encountered and colonized. In this review, we discuss the lifecycle of L. pneumophila and the molecular regulatory network that senses nutritional depletion via the stringent response, a link to stationary phase‐like metabolic changes via alternative sigma factors, and two‐component systems that are homologous to stress sensors in other pathogens, to regulate differentiation between the intracellular replicative phase and more transmissible states. Together, we highlight how this prototypic intracellular pathogen offers enormous potential in understanding how molecular mechanisms enable intracellular parasitism and pathogenicity.
Etiology, risk factors and management of hypertension post liver transplantation
Authors: Braekman Eline , De Bruyne Ruth , Vandekerckhove Kristof , Prytula Agnieszka 
Published: November 2023

AbstractBackgroundCardiovascular events are one of the most important causes of morbidity and mortality in the long‐term follow‐up of liver transplant recipients. Hypertension is a significant cardiovascular risk factor that occurs frequently after pediatric liver transplantation. Chronic use of immunosuppressants – mainly calcineurin inhibitors – plays a major role in the development of post‐transplant hypertension and circadian disturbances such as flattening of the nocturnal blood pressure dip. This requires special attention in children given the long timeframe during which immunosuppressive therapy is necessary. Careful and structured blood pressure monitoring and adequate treatment of hypertension are essential to optimize the quality of life and life expectancy of pediatric liver transplant patients. However, evidence‐based guidelines for monitoring and management of post‐transplant hypertension and its complications are lacking.MethodsWe conducted a comprehensive review of the current knowledge and practices concerning post‐transplant hypertension. The databases Pubmed, Embase, Web of Science and Google Scholar were scanned with the following keywords: pediatric liver transplantation, immunosuppression, tacrolimus, cardiovascular effects, hypertension, heart function, kidney function, circadian rhythm, mechanism, monitoring, and management.ResultsIn this review, we describe the incidence and etiology of hypertension in pediatric liver transplant recipients, the underlying mechanisms and characteristics of calcineurin inhibitor‐induced hypertension, and the consequences of and risk factors for post‐transplant hypertension. We hereby present an overview of the current practices in blood pressure monitoring and antihypertensive treatment as well as an algorithm for the evaluation and management of hypertension post liver transplantation. Finally, we discuss knowledge gaps and suggestions for future research.
Women's philanthropy and religion: The ladies of the Northampton shoe trade, 1870–1950
Authors: Perry Kathrina 
Published: November 2023

AbstractThis paper considers the role in which women played within religious organisations within the 19th and 20th centuries. Using the Northampton Boot and Shoe industry as a focus, it will explore the philanthropic activities carried out by women connected to the industry, and how they were able to support the local churches. The paper also considers the importance of women's history within a local history study as well as showing women's contribution to society and their local community.
Clade 2.3.4.4 H5 chimeric cold-adapted attenuated influenza vaccines induced cross-reactive protection in mice and ferrets
Authors: Sun Weiyang , Xu Jiaqi , Wang Zhenfei , Li Dongxu , Sun Yue , Zhu Menghan , Liu Xiawei , Li Yuanguo , Li Fangxu , Wang Tiecheng , Feng Na , Guo Zhendong , Xia Xianzhu , Gao Yuwei 
Published: November 2023

ABSTRACT
Clade 2.3.4.4 H5Nx subtype avian influenza viruses (AIVs) have circulated in poultry and wild birds worldwide. Recently, an increasing number of H5Nx human infection cases have been reported occurred. Live attenuated influenza vaccines demonstrate more advantages than other types of vaccines, such as ease of administration, elicitation of systemic immune responses, and the ability to generate breadth protection. However, the attenuated viruses also bear the risk of reassortment with the wild-type influenza A virus. To overcome this reassortment problem, we designed and constructed Clade 2.3.4.4 H5 chimeric cold-adapted attenuated influenza vaccines (CAIVs) by introducing the hemagglutinin ectodomains of H5N6 into a cold-adapted attenuated master donor of an influenza B virus. These H5 CAIVs induce humoral antibody response, mucosal immune response, and cellular immune response in mice models. After two doses were administered in mice, H5 CAIVs provided cross-protection responses with 100% survival against wild-type Clade 2.3.4.4 H5 subtype AIVs. The immunized mice exhibited more significant reductions of lung viral titers or lung pathology than those in the mock group mice. In ferret models, Clade 2.3.4.4b and 2.3.4.4h H5 CAIVs produced a cross-protective efficacy against wild-type Clade 2.3.4.4b and Clade 2.3.4.4h H5 AIVs. The findings of the current study indicate that our H5 CAIVs may have the potential to prevent and control H5Nx influenza viruses in humans.

IMPORTANCE
Clade 2.3.4.4 H5Nx avian influenza viruses (AIVs) have circulated globally and caused substantial economic loss. Increasing numbers of humans have been infected with Clade 2.3.4.4 H5N6 AIVs in recent years. Only a few human influenza vaccines have been licensed to date. However, the licensed live attenuated influenza virus vaccine exhibited the potential of being recombinant with the wild-type influenza A virus (IAV). Therefore, we developed a chimeric cold-adapted attenuated influenza vaccine based on the Clade 2.3.4.4 H5 AIVs. These H5 vaccines demonstrate the advantage of being non-recombinant with circulated IAVs in the future influenza vaccine study. The findings of our current study reveal that these H5 vaccines can induce cross-reactive protective efficacy in mice and ferrets. Our H5 vaccines may provide a novel option for developing human-infected Clade 2.3.4.4 H5 AIV vaccines.
Supplemental Material: Expanding the metamorphic devolatilization model: Komatiites as a source for orogenic gold deposits in high-grade metamorphic rocks
Authors: Yu Chang , Zhong Richen , Chen Yanjing , al. et 
Published: November 2023

<p>File S1: Detailed description of simulation methods. File S2: Gold contents of volcanic rocks in West Australian Craton. File S3: Bulk rock water contents of komatiites in global greenstone belts. Data for Files S2 and S3 are compiled from GEOROC database. </p>
Large rapidity gaps in proton–nucleus interaction
Authors: Khoze V. A. , Ryskin M. G. 
Published: November 2023

AbstractWe analyse the cross-section of events with Large Rapidity Gaps observed in proton–lead collisions by the CMS Collaboration (arXiv:2301.07630). The role of the transverse size of elementary pN amplitude is discussed. We emphasize that the cross-section of incoming proton dissociation caused by the photon radiated off the lead ion is close to the value of $$d\sigma /d\Delta \eta ^F$$

d
σ
/
d
Δ

η
F

measured by the CMS, and it is not clear why there is no room in the data for the Pomeron-induced contribution
Temporal Trends in Public Stroke Knowledge, 1995–2021
Authors: Robinson David J. , Ding Lili , Rademacher Eric , Stanton Robert , Anderson Aaron M. , Khoury Jane C. , Broderick Joseph P. , Kissela Brett M. , Kleindorfer Dawn 
Published: November 2023

BACKGROUND:
Outreach campaigns have sought to reduce the burden of stroke by improving knowledge of stroke risk factors (RF) and warning signs (WS). We describe trends in stroke knowledge from 1995 to 2021.

METHODS:
From 1995 to 2021, 6 separate surveys were conducted in the Greater Cincinnati Northern Kentucky Region. Temporal trends in RF/WS knowledge were analyzed using logistic regression adjusting for Race, sex, age, and education.

RESULTS:

In 1995, 28.6% of participants (537/1880) could name ≥2 WS, compared with 50.6% (983/1944) in 2021 (trend
P
<0.0001 after adjustment). In 1995, 44.5% of participants (836/1880) knew ≥2 RF, compared with 56.7% (1103/1944) in 2021 (trend
P
<0.0001 after adjustment). Although still improved compared with 1995, fewer participants could identify ≥2 RF in 2021 (1103/1944, 56.7%) when compared with 2011 (1287/2036, 63.2%, pairwise
P
<0.05). This decline in RF knowledge was disproportionately larger in women (odds ratio of 0.67 for knowledge in 2021 compared with 2011 in females,
P
=0.047 for the interaction between sex and study year).

CONCLUSIONS:
Although stroke knowledge has overall improved since 1995, there is evidence for lost gains since 2011, particularly in women. Stroke outreach campaigns need ongoing evaluation.