bluuebunny/crossref_metadata_2025_split huggingface dataset:
Larvicidal activity ofTrichoderma atroviride(Hypocreales: Hypocreaceae) againstAedes albopictus(Diptera: Culicidae)
Authors: Hayes David T. , Tawidian Patil , Schubert Ethan , Kang Qing , Sumpter Amare J. , Michel Kristin 
Published: January 2025

AbstractLarviciding is an important part of effective integrated mosquito management. However, growing resistance to chemical and bacterial-based insecticides requires biocontrol agents with novel modes of action. Entomopathogenic fungi are good candidates for larval control due to their capability to infect mosquito larvae and their production of larvicidal compounds. In this study, we isolated a strain ofTrichoderma atroviridefromAedes albopictuslarvae collected in Manhattan, KS, USA. We used a laboratory-based microcosm assay to expose L3Ae. albopictuslarvae toT. atrovirideconidia and culture supernatant treatments. Larvae were monitored daily for survival and development to pupae and adults. In addition, adult survival was monitored for ten-days post pupation, and wing lengths were measured to assess mosquito size. Our results revealed thatT. atrovirideculture supernatant was a potent larvicide towardsAe. albopictus. However, conidia by themselves were not larvicidal, indicating the major mode of killing was through toxicity exerted by the culture supernatant. We further showed that larval exposure toT. atroviridesupernatant delayed larval development to pupae. Sex-specific adult survival was not affected by larval exposure toT. atroviride. However, wing length of male and female mosquitoes were reduced, indicating a reduction in adult mosquito body size as compared to the control. Taken together, this study identifies the culture supernatant from a novel strain ofT. atrovirideas a potent larvicide ofAe. albopictus, potentially expanding our toolbox for biological control of mosquitoes.
Cannabinoid Modulation of Central Amygdala Population Dynamics During Threat Investigation
Authors: Yasmin Farhana , Naskar Saptarnab , Rosas-Vidal Luis E. , Patel Sachin 
Published: January 2025

ABSTRACTCannabinoids modulate innate avoidance, threat-reactivity, and stress adaptations via modulation amygdala-associated circuits; however, the mechanisms by which cannabinoids modulate amygdala representation of threat-related behavior are not known. We show that cannabinoid administration increases the activity of central amygdala (CeA) somatostatin neurons (SOM) and alters basal network dynamics in a manner supporting generation of antagonistic sub-ensembles within the SOM population. Moreover, diverging neuronal population trajectory dynamics and enhanced antagonistic sub-ensemble representation of threat-related behaviors, and enhanced threat-related location representation, were also observed. Lastly, cannabinoid administration increased the proportion of SOM neurons exhibiting multidimensional representation of threat-related behaviors and behavior-location conjunction. While cannabinoid receptor activation ex vivo suppressed excitatory inputs to SOM neurons, our data suggest preferential suppression of local GABA release subserves cannabinoid activation of CeA SOM neurons. These data provide insight into how cannabinoid-mediated presynaptic suppression transforms postsynaptic population dynamics and reveal cellular mechanisms by which cannabinoids could affect threat-reactivity.
ca-circSCN8A promotes PASMCs ferroptosis via LLPS initiated R-Loop
Authors: Li Mengnan , Hao Yingying , Song Xinyue , Liu Huiyu , Zhang Chi , Zhang Jiaqi , Sun Hanliang , Zheng Xiaodong , Zhang Lixin , Yu Hang , Ma Cui , Zhao Xijuan , Zhu Daling 
Published: January 2025

ABSTRACTBACKGROUNDFerroptosis has been implicated in pulmonary hypertension. Chromatin-associated RNAs are linked to ferroptosis. However, their role in pulmonary vascular ferroptosis in PH is unexplored.METHODSBioinformatics, Sanger sequencing, RNase R and others were employed to identify differentially higher expression of ca-circSCN8A. Functional gain and loss assays were employed to unveil the role of ca-circSCN8A in hypoxia-induced redox-dependent ferroptosis in HPASMCs and PH mice model. Interaction between ca-circSCN8A and FUS was detected via RNA immunoprecipitation and pull-down assays. FRAP, CHIRP-qPCR, MDA, GSH and GSSG were conducted to explore the potential molecular mechanism.RESULTSca-circSCN8A was firstly identified and confirmed to be upregulated in PH. Upregulation of ca-circSCN8A can promote hypoxia induced ferroptosis in HPASMCs. Under hypoxic conditions, ca-circSCN8A promoted the lactylation of FUS by recruiting EP300, leading to formation of LLPS of ca-circSCN8A/FUS/EP300. LLPS maintained the stability of the R-Loop formed by ca-circSCN8A and ferroptosis related-gene SLC7A11 promoter that inhibit the transcription of the SLC7A11 gene, further result in the disruption of the redox balance and causes ferroptosis in HPASMCs.CONCLUSIONSca-circSCN8A recruits EP300 to promote the lactylation of FUS, thereby promoting LLPS formation of ca-circSCN8A/EP300/FUS. Further, the LLPS motivates ca-circSCN8A to form R-loop with its non-host SLC7A11 and participating in the regulation of hypoxic induced HPASMCs redox-dependent ferroptosis. This is the first confirmation that circRNAs forming R-loops with non-host genes regulated by LLPS. Our findings indicated that ca-circSCN8A plays an important role in ferroptosis of hypoxic induced HPASMCs and may be a potential target for the treatment of PH.
Generation of aNr2f2-driveninducible Cre mouse to target interstitial cells in the reproductive system
Authors: Brown Paula R. , Estermann Martin A. , Gruzdev Artiom , Scott Gregory J. , Hagler Thomas B. , Ray Manas K. , Yao Humphrey Hung-Chang 
Published: January 2025

AbstractThe orphan nuclear receptorNr2f2, also known as COUP-TFII, play important roles in development and function of multiple organs, including the reproductive system. NR2F2 is expressed in the interstitial cells of both embryonic and adult testes, ovaries, and reproductive tracts. Taking advantage of such unique expression pattern, we have developed a tamoxifen inducible Cre model,Nr2f2-iCreERT2, which specifically and efficiently targets interstitial cells in both male and female reproductive organs across embryonic and adult stages. This model offers a powerful tool for gene knockout studies specifically in the interstitial compartment, without affecting the supporting or germ cells. Additionally, it enables interstitial cell lineage tracing, facilitating the assessment of the interstitial’s contribution to non-interstitial cell types during development and differentiation.
Tailoring the digital pitch: gender-specific strategies for maximizing social media ad impact on purchase intention
Authors: Wei Lee Heng , Kian Lam Tan , Mey Lau Pei 
Published: January 2025

PurposeThis study explores the influence of gender-specific reactions to social media advertisements on purchase intentions, addressing a gap in existing research. It examines how these reactions affect the perceived value of ads and, consequently, the intention to purchase, with a particular focus on gender as a moderating factor. The primary aim is to analyse how gender moderates the relationship between consumers’ perceptions of the value of social media ads and their subsequent purchase intentions.Design/methodology/approachA non-probability convenience sampling method was employed to collect data from 423 social media users in Malaysia at shopping malls. Respondents interacted with advertisements on Facebook, Instagram or TikTok and completed a survey. Descriptive analysis was performed using SPSS 25. The study utilized structural equation modelling (SEM) to test the structural and measurement models. Multigroup analysis (MGA) was conducted using SMART-PLS 4.0.9.6 to assess moderation effects based on gender differences.FindingsThe findings reveal that advertisements emphasizing entertainment significantly influence female purchase intentions, whereas ads highlighting product or service values resonate more with males, challenging common stereotypes. Informative and creative ads show universal appeal across genders, underscoring the importance of diverse ad elements in shaping consumer behaviour.Originality/valueThis study advances the advertising value model by specifically identifying gender-based differences in how entertainment and perceived value in social media ads influence purchase intention. It uniquely reveals that females are more responsive to entertainment-focused and value-conscious ads. These findings provide targeted strategies for advertisers to design gender-sensitive campaigns, enhancing the model’s relevance in contemporary digital advertising contexts.
Impact media portrays on police legitimacy in times of emergencies: a global perspective
Authors: Asad Muhammad Mujtaba , Zia Sumaira 
Published: January 2025

PurposeThe swift development of digital platforms and the intricate nature of socialization processes have greatly impacted how young people perceive the legitimacy of the police. This study investigates the influence of different media platforms and methods of socialization in emergencies on the attitudes and beliefs about law enforcement among young individuals. The aim of this review paper is to consolidate existing literature on the influence of various forms of media and social contacts shaping youth attitudes towards the legitimacy of the police, within distinct social and cultural contexts.Design/methodology/approachThe literature was reviewed narratively, with a focus on major digital bibliographic databases for the purpose of selecting studies. This approach facilitated the examination of overarching concepts across several fields of study in order to develop a thorough comprehension of how media and socialization in emergencies influence young people’s perceptions of the legitimacy of the police. Three major themes were discovered, encompassing the connection of three different theories with the youth perceptions of police legitimacy, impacts from different media sources like news, entertainment and social media and the influence of important socialization agents like family, peers and community.FindingsThe review confirms that the media, regardless of whether it presents good or bad images, has a major impact on the views of youngsters towards the police. It influences their opinions of how trustworthy and legitimate the police are. Modeling and reinforcement, which are key components of social learning, play a crucial role in influencing the impact of media on young people. Community and family connections have significant influence, either strengthening or lessening the effects of media depictions. Although media has the ability to promote understanding and regard for law enforcement, it was also observed that there are challenges associated with the reinforcement of preconceptions and biases.Practical implicationsThis research offers fundamental ideas for creating educational and community initiatives that improve positive media depictions of law enforcement and bolster community–police interactions. Additionally, it provides a framework for future studies on media approaches that could facilitate the development of a well-rounded understanding of the legitimacy of law enforcement among young people.Originality/valueThis literature review combines social learning and cognitive theories with empirical research on media to examine the complex and varied effects of media and socialization on how young people perceive the legitimacy of the police. It emphasizes the necessity for a sophisticated comprehension of these connections within the framework of current social dynamics and advancements in technology.
Unveiling user intentions: an integrated analysis of hedonic motivation and service quality in e-grocery technology acceptance
Authors: Pagnanelli Maria Anna , Colamatteo Annarita , Cassia Fabio , Sansone Marcello 
Published: January 2025

PurposeThis study aims to extend the Technology Acceptance Model 2 (TAM2) by incorporating hedonic motivation and service quality and exploring their collective impact on users’ continuance intention in the context of e-grocery. The purpose is to provide a comprehensive understanding of the factors influencing e-grocery technology acceptance.Design/methodology/approachThe empirical analysis follows a cross-sectional design, using data collected in Italy from January to March 2023. The survey, utilizing the convenience sampling method, focuses on users who have made online grocery purchases in the previous six months. Data analysis employs partial least squares structural equation modelling (PLS-SEM), which enables causal-predictive model assessment.FindingsThe research reveals significant relationships among hedonic motivation, service quality, perceived ease of use, perceived usefulness and continuance intention. Hedonic motivation positively impacts perceived usefulness but not perceived ease of use. Service quality significantly influences both perceived ease of use and perceived usefulness. Additionally, perceived ease of use positively influences perceived usefulness and continuance intention, while perceived usefulness significantly impacts continuance intention.Research limitations/implicationsThe cross-sectional design could limit the study’s ability to capture the evolution of users’ continuance intention over time. Cultural influences on users’ perceptions could be explored further to develop context-specific strategies.Practical implicationsThe findings emphasize the importance of hedonic motivation, service quality, ease of use and perceived usefulness in shaping users’ intentions to continue using online grocery services. Practitioners are encouraged to focus on enhancing hedonic elements for increased user loyalty and invest in service quality, particularly in customer care and checkout processes, to improve user perception and ease of use.Originality/valueThis study contributes to the existing literature by integrating hedonic motivation and service quality into TAM2, offering a novel perspective on their combined impact on technology acceptance. The inclusion of these factors enhances the model’s applicability in understanding user behaviour in the adoption of technology, specifically in the e-grocery sector.
Adoption of ISSB standards in emerging markets – insights from Moroccan companies’ organizational readiness
Authors: Benhayoun Issam , El Amrani Mehdi , Barhdadi Aya , Azzaoui Walid 
Published: January 2025

Purpose
This study aims to investigate the organizational factors determining Moroccan companies’ readiness to adopt the newly introduced International Sustainability Standards Board (ISSB) standards (International Financial Reporting Standards S1 and S2), focusing on absorptive capacity, organizational structure and size and culture and finally kakistocracy.

Design/methodology/approach
The research uses a quantitative approach to analyze the impact of specific organizational factors on the readiness to adopt ISSB standards by Moroccan companies. A partial least squares structural equation modeling based on a sample size of 150 Moroccan accounting professional was performed to assess the factors affecting readiness.

Findings
The results of the study highlight that absorptive capacity is the most significant predictor of readiness for ISSB standards adoption, with a strong positive effect and high statistical significance. Organizational structure, size and culture also positively influence readiness, though to a lesser extent. Kakistocracy has a minimal impact, suggesting its influence is limited in this context. Overall, the findings emphasize the critical role of organizational learning and structure in driving readiness, while governance issues appear to play a marginal role.

Research limitations/implications
The study’s limitations include the potential interaction with unmeasured variables and the reliance on self-reported data, which may introduce biases. Future research should explore additional variables and incorporate qualitative methods for deeper insights.

Practical implications
Policymakers should prioritize enhancing firms’ absorptive capacities through organizational improvements and targeted support while recognizing governance reforms as a secondary priority. Efforts should address barriers to ISSB adoption, such as resource limitations, regulatory alignment and stakeholder engagement, to facilitate effective integration of sustainability standards in emerging economies.

Originality/value
This research enriches academic discourse by providing insights into how emerging markets adapt to global sustainability frameworks. It serves as a benchmark for similar economies, guiding policymakers and corporate leaders on best practices and promoting transparency and trust among stakeholders.
Imagination workshops as a creative method for exploring the sociomaterial dimensions of privacy
Authors: Horppu Johanna 
Published: January 2025

Purpose
The purpose of this paper is to introduce imagination workshops as a creative method for studying privacy from a sociomaterial perspective. The workshops incorporate a creative element – the imagination game – into a traditional focus group setting. The imagination game is a role-playing card game that involves participants imagining scenarios set in the future.

Design/methodology/approach
The imagination workshop method is illustrated through an empirical study exploring imaginaries of the future smart home. The study encompasses five workshops with a total of 46 participants.

Findings
The findings from the empirical application of the method highlight its strengths in uncovering thoughts and feelings related to human–data relations that might be difficult to attain through more conventional methods, such as affective responses to privacy dilemmas. By combining imagination and collaborative activity, less taken-for-granted ideas can be tapped into.

Originality/value
The paper contributes to consumer research by introducing a novel qualitative method for studying privacy. By drawing from a new materialism perspective, the imagination workshops bring to light the sociomaterial dimensions of privacy that extend beyond mere cognitive decision-making processes. In this way, the method can be applied to reveal the dynamic and visceral nature of the construct. In addition to privacy research, the method provides ample opportunities for application in diverse contexts interested in technological futures.
Optimizing and predicting tenacity of multicomponent hybrid high-performance yarn using Box-Behnken design
Authors: Islam Md Azharul , Rathour Rochak , Kumar Bipin , Das Apurba , Kumar Nandan 
Published: January 2025

Purpose
This work focuses on optimizing and predicting the tenacity of twin-sheath single-core hybrid yarn. This study aims to predict and maximize yarn performance by investigating key factors influencing yarn tenacity.

Design/methodology/approach
Three critical parameters − ultra-high molecular weight polyethylene (HPPE) denier, stainless steel micron size and twist per meter − were considered for making multicomponent yarn and optimized using the Box-Behnken design (BBD), a response surface methodology variant. The hybrid yarn studied consists of a stainless-steel core, a polyester inner layer and an HPPE outer layer with opposite twists. The ASTM D2256 method was applied on Instron 3365 machine to measure yarn tenacity.

Findings
The optimized yarn setup involved 200 twists per meter, 400 Den HPPE and 45-micron stainless steel, resulting in a 127.5 cN/Tex tenacity. The quadratic model best fits the data, with R² values close to 1.00 (R² = 0.9935, adjusted R² = 0.9817, projected R² = 0.8956), a lower PRESS value of 445, a higher adequacy precision of 19.6816 and a higher TPC percentage of 35.23%. The analysis of variance results confirmed the model significance (F-value = 84.75, P-value < 0.0001), and the average relative error was found to be 3.43%, indicating predictive accuracy.

Originality/value
This study demonstrates the effectiveness of the BBD in optimizing hybrid yarn tenacity, providing valuable insights in terms of core yarn and outer sheath yarn linear density with twist per meter. The work presents a novel approach to hybrid yarn optimization and prediction, expanding the potential for further research and development in textile engineering.
Dude sponsored: how executive function and disclosures moderate the persuasive effects of sponsored online videos on young adults
Authors: Lapierre Matthew A. , van Reijmersdal Eva A. , Boerman Sophie C. 
Published: January 2025

Purpose
This study aims to examine how individual differences and contextual factors affect audience responses to sponsored video content. Specifically, this study tests whether executive function (EF, both hot and cool) skills in young adults influence persuasion knowledge and advertising responses. The study further tests the moderating role of disclosure presence and country of participants (US vs The Netherlands).

Design/methodology/approach
An online experiment (N = 368) with a 2 (disclosure: present versus absent) × 2 (country: US versus The Netherlands) between subjects design featuring young adults (M age = 21.06; SDage = 3.06) is conducted.

Findings
Participants with more advanced cool EF showed a better understanding of the persuasive intent of the video, and hot EF was associated with higher brand recall. In addition, disclosures only enhance the understanding of persuasive intent of the video for people with less advanced levels of hot EF. Lastly, Dutch participants were more responsive toward the disclosure.

Originality/value
This study provides key insights regarding how young adults process sponsored content and the role that cognition plays in shaping responses.
Advances in understanding dietary fiber: Classification, structural characterization, modification, and gut microbiome interactions
Authors: Feng Yiming , Jin Qing , Liu Xuanbo , Lin Tiantian , Johnson Andrea , Huang Haibo 
Published: January 2025

AbstractGut microbiota and their metabolites profoundly impact host physiology. Targeted modulation of gut microbiota has been a long‐term interest in the scientific community. Numerous studies have investigated the feasibility of utilizing dietary fibers (DFs) to modulate gut microbiota and promote the production of health‐beneficial bacterial metabolites. However, the complexity of fiber structures, microbiota composition, and their dynamic interactions have hindered the precise prediction of the impact of DF on the gut microbiome. We address this issue with a new perspective, focusing on the inherent chemical and structural complexity of DFs and their interaction with gut microbiota. The chemical and structural complexity of fibers was thoroughly elaborated, encompassing the fibers’ molecular composition, polymorphism, mesoscopic structures, porosity, and particle size. Advanced characterization techniques to investigate fiber structural properties were discussed. Additionally, we examined the interactions between DFs and gut microbiota. Finally, we summarized processing techniques to modify fiber structures for improving the fermentability of DF by gut microbiota. The structure of fibers, such as their crystallinity, porosity, degree of branching, and pore wettability, significantly impacts their interactions with gut microbiota. These structural differences also substantially affect fiber's fermentability and capability to modulate the composition of gut microbiota. Conventional approaches are not capable of investigating complex fiber properties and their influences on the gut microbiome; therefore, it is of the essence to involve advanced material characterization techniques and artificial intelligence to unveil more comprehensive information on this topic.