bluuebunny/crossref_metadata_2025_split huggingface dataset:
Systematically Study and Practice for Thermal Well Integrity in Liaohe Oilfield
Authors: Tong Deshui , Liu Mingtao , Xiong Jimin , Chen Ping 
Published: November 2023

Abstract
Liaohe Oilfield has developed heavy oil for more than 40 years, and accumulated a lot of experience in research and practice for well integrity under Cyclic Steam Stimulation, Steam Flooding, SAGD, In-situ Combustion. This paper will introduce the systematical achievements, including well completion design, casing selection, cementing slurry, string attachment, etc.
Based on the continuous study of fundamental principles, thermal casing, details of pre-stress method and industrial evaluation, the well completion design method has been optimized and the practicality has been checked ultimately. In particularly, the pre-stress method has been deeply studied through experiments and calculations. We have made a further improvement on string attachments. According to thermal recovery environment and low-cost requirement, a Portland cementing slurry characterized with low Young’s modulus, high compressive strength, and good temperature resistance, has been researched and used in field.
The pre-stress method for the completion string design is testified to be effective in some extent, because the stress pre-imposed can reduce the string stress and minimize the wellhead growth in thermal recovery. The newly researched cementing slurry has been systematically tested in laboratory, the results are excellent: Young’s modulus ≤6, compressive strength ≥21MPa, temperature resistance 350°C, cost lower than 1000$/t. Casing used in thermal well should have a good performance of collapse strength, and the thickness to diameter ratio is important as well as the premium connection. The newly designed anchor with 6-cylinder anchor claws attached the completion string can adapt with softy and hard stratum. With the standardization of all the measures used in Liaohe oilfield, the thermal well integrity becomes better and better. The statistical data shows that the casing damage rate lowered 34%, and the life of the thermal well prolonged at least 2 years on average.
Some contents in this paper are novel, such as the result of the pre-stress experiment, Portland cementing slurry with low-cost and good performance, newly designed anchor, etc. We believe all the experience accumulated and introduced in this paper could give some useful directives for thermal well integrity all over the world.
Wireline Surveillance Operations with Minimum Impact to Production
Authors: Mussayev G. , Saduakassov B. , Nurmukhanbetov A. , Morrison A. , Seitmaganbetov N. , Darmentayev S. , Suleimenov O. , Kulshinbayev N. , Williams D. , Simaganbetov D. , Ismailov B. , Timonin A. , Adilkhanov A. , Mukashev A. 
Published: November 2023

Abstract
This paper is aimed to share recent best practices in wireline well interventions in Tengiz field, specifically aimed to reduce the intervention impact to LPO (Loss Production Opportunity). Three main practices will be shared:
Installation of protecting cages to conduct wireline interventions on MWPs. TCO has Multi-WellPad (MWP) facilities with a number of wells that hooked up into one production system. TCO must collect subsurface data for RoK requirements and Reservoir Management. In the past, TCO had to shut-in entire MWP to execute surveillance operations, which would negatively impact production. An intermediate improvement was to shut-in adjacent neighbor wells if any intervention scope on the working well is required, with the aim for the team to review the procedure to identify possible methods and safeguards to allow continued production to those adjacent wells to mitigate production impact. Previously, TCO could flow the well at a minimum rate in a smaller ID completion to control lifting forces, but by utilizing a different cable and logging unit provided a safer execution of PLT logging in high-rate wells that reduced uncertainties of zonal allocation and provided more accurate data. Utilization of combined PLT, RST and HFND logging tools string to maximize gathering of quality information with minimum well downtime. Using heavy cable to conduct high-rate production logging in small diameter liners. To minimize well downtime during wireline surveillance, we offer PLT\RST\Noise tool into one toolstring within taller lubricator. Combination of 3 tools provide large picture in wider range with minimum well downtime.
This paper aims to provide an overview on the surveillance operations processes improvements and to share the best practices in planning of operational activities at the field with minimized impact on overall field production.
Enhanced Oil Recovery Method for Highly Viscous Oil Reservoirs Based on In-Situ Modification of Physico-Chemical Properties
Authors: Veliyev E. F. , Askerov V. M. , Aliyev A. A. 
Published: November 2023

In recent decades, there has been a significant and ongoing increase in the demand for hydrocarbons, notably oil. According to OPEC, this demand is projected to rise by 16.4 million barrels per day by 2040. In comparison, the daily hydrocarbon consumption, which stood at 99.2 million barrels in 2021, is expected to surge to 109.4 million barrels per day by 2040 [1]. This escalating demand presents a unique set of challenges for oil-exporting nations. The conventional exploitation of light oil fields falls short in addressing these challenges.
Researchers continually strive to meet the escalating demand for hydrocarbon energy sources through innovative field exploitation and development methods [2-6]. However, despite the promise of these technologies, they do not offer comprehensive solutions [7-13]. Consequently, enhancing the efficiency of heavy oil field development emerges as the most pragmatic alternative [14-15].
Heavy oil, characterized by a density of 20°API or lower and a viscosity exceeding 100 mPa*s, owes its properties to the elevated concentration of tar-asphaltene components. Developing heavy oil fields is considerably more complex compared to light oil fields due to these distinctive characteristics [16-21]. Additionally, the methods to boost oil production from heavy oil reservoirs are limited.
Field Trial of LWD NMR Tool for Accurate Estimation of Effective Porosity in Deviated HPHT Wells: A Viable Alternative to Wireline-Based NMR Tools
Authors: Kabiyev Y. , Manakhayev R. , Kazhgaliyev M. 
Published: November 2023

Abstract
The Tengiz reservoir is known for its substantial bitumen content, requiring careful differentiation during formation evaluation processes. To accurately estimate the effective porosity, wireline nuclear magnetic resonance (NMR) tools were used in conjunction with other logging tools. However, the increasing number of deviated wells drilled in Tengiz posed conveyance challenges for the wireline-based NMR tool due to high deviation angles. In light of this, TCO (Tengizchevroil) geoscientists sought opportunities to acquire NMR data using logging-while-drilling (LWD) technology in the reservoir section. Although the LWD NMR tool was not previously available for the required hole size, recent commercialization made it feasible.
A team of geoscientists at TCO meticulously planned and executed a field trial of the LWD NMR tool to assess its potential future utilization in situations where the conveyance of wireline NMR tools may encounter difficulties. The LWD NMR tool was successfully deployed in a deviated well during drilling operations, followed by a subsequent measurement after drilling (MAD) pass to ensure log quality control. To verify and compare the acquired data, wireline-based NMR measurements were also conducted in the same well.
The results of the field trial demonstrated the successful acquisition of high-quality LWD NMR data, corroborated by the MAD pass data and wireline log data. Furthermore, we revised and tested internal NMR data processing workflows, which conclusively established LWD NMR as a viable alternative to wireline-based NMR tools.
Notably, the acquisition of NMR data while drilling offers additional benefits, as the near wellbore zone is not fully flushed with drilling mud, potentially enhancing fluid typing techniques (T1 and T2 distribution). This promising outcome opens up new avenues for more efficient and reliable estimation of effective porosity in deviated wells, as well as in wells with potential restrictions to run WL tools within the Tengiz reservoir and beyond, contributes to improved reservoir characterization and decision-making processes in asset development.
Predicting distribution and establishment of two invasive alien Daphnia species in diverse lakes in New Zealand-Aotearoa
Authors: Burns Carolyn , Rees Andrew , Wood Susie 
Published: November 2023

Abstract

The freshwater zooplankton of New Zealand-Aotearoa are species-poor with only two indigenous Daphnia species: D. thomsoni, and D. tewaipounamu which was discovered in a few subalpine lakes in 2016. Over the last two decades two species of invasive non-indigenous Daphnia, D. pulicaria/pulex and D. galeata, have become well established in the plankton of many lakes in New Zealand-Aotearoa and their distribution appears to be increasing rapidly. We report the current distribution of these two invasive species in approximately 300 lakes throughout New Zealand-Aotearoa and test the hypothesis that the distribution and establishment of these invaders is more closely related to human access to a lake than to any environmental attributes of a lake’s water or biota and consider potential implications of our findings for lake management. Although canonical variates analysis and boosted regression trees did not identify human access as an important predictor, both invasive Daphnia occurred significantly more often in lakes within 200 m of a road, consistent with our hypothesis that humans and their recreational activities are the most likely vectors and facilitators of the distribution of these Daphnia in New Zealand-Aotearoa. Critically, D. galeata's realised niche completely envelopes D. thomsoni's, which could force the native species to become extinct through competitive exclusion. These results suggest that the spread of D. pulicaria and D. galeata to lakes where they do not yet occur is unlikely to be prevented unless public access to these waterways is denied or strictly controlled.
Carbon Black: A Thermally Conductive Reinforcement for Epoxy Based Composite
Authors: SAHOO BIBEKANANDA , Patel Pooja , Nanda Bishnu Prasad 
Published: November 2023

Abstract

Heat conduction plays a vital role in the performance and durability of any component. A wide range of applications is available which demand a good heat conduction ability. The property used to understand the heat conduction behavior in a solid is called effective thermal conductivity (Keff). It is recommended to reinforce an adequate amount of filler material in the matrix to increase the Keff of the composite. The current study used carbon black (CB) particulates, a by-product of waste tyre pyrolysis, as the reinforcing agent in the epoxy resin. The composites are prepared by solution casting method with different volume % of filler. To study the thermal behavior of samples, effective thermal conductivity, glass transition temperature (Tg), and co-efficient thermal expansion (CTE) are measured as a function of vol. % of filler. After plotting the experimental result, it is noticed that the Keff and Tg are increased, and CTE is decreased with an increase in vol. % of CB. The percolation threshold is also calculated from Keff vs. vol. % curve. Various mathematical models are incorporated to verify the experimental results of effective thermal conductivity. A finite element method (FEM) based numerical model is also developed to study the thermal conductivity behavior of composites. ANSYS MECHANICIAL APDL is used for the FEM analysis. The FEM results showed a marginal variation from experimental data at 0.9928 vol. % of CB. The reason behind this is the formation of voids during sample making, the effect of which is not taken in FEM.
Participation in activities among people with long-term spinal cord injury in Sweden and in the USA - A secondary data analysis.
Authors: Lundström Ulrica , Dashner Jessica 
Published: November 2023

Abstract
Study design
Secondary analysis.
Objective
To explore differences in participation, secondary health complications, and the use of assistive devices and personal assistance among people with long-term SCI in Sweden and the USA.
Methods
Secondary analysis of data collected via PARTS-Mv3 among individuals living with SCI in Sweden (n = 73) and in the USA (n = 45). Descriptive analyses provided information regarding the participants, their participation in activities, and secondary health complications, together with the use of assistive devices and personal assistance.
Results
Both samples included more males than females. The mean ages for the Sweden and USA samples were 63.7 and 58, respectively. The mean duration since injury was 36.3 years for Sweden and 35.9 for the USA. Perceived health was significantly higher in Sweden (3.80) than in the USA (2.89). The USA sample reported higher occurrence of secondary health complications than Sweden. The amount and type of participation in activities varied between countries, so also the use of assistive devices and personal assistance.
Conclusions
Participation differences were identified when comparing individuals with long-term SCI living in Sweden in the USA. Further work is needed to determine whether the differences can be attributed to the varying social policies and health care systems of each country. Understanding how cultural differences influence participation can provide valuable information to determine which system is likelier to positively influence the participation of individuals with long-term SCI.
LRG1 is a novel HER3 ligand and promotes growth in colorectal cancer
Authors: Wang Rui , Rathore Moeez , Wright Michel’le , Huang Wei , Martin Daniel , Taylor Derek , Miyagi Masaru , Tang Wen , Feng Hao , Li Yamu , Wang Zhenghe , Ellis Lee , Winter Jordan , Moss Stephen , Greenwood John 
Published: November 2023

Abstract
HER3 signaling pathway plays a major role in promoting the development of metastatic colorectal cancer (mCRC). Here, we demonstrated that endothelial cells, a key component of the liver microenvironment, secrete leucine-rich alpha-2-glycoprotein 1 (LRG1) that activates HER3 as a ligand, distinct from the canonical HER3 ligand neuregulins. Blocking LRG1 in host animals either by gene knockout or a neutralizing antibody significantly blocked outgrowth of CRC liver metastases and prolonged mouse survival. We also identified eIF4B-mediated protein synthesis as a downstream target of LRG1-HER3 interactions, and determined PI3K-PDK1-RSK as the mediating signaling axis. Our findings identify LRG1 as a key mediator of liver-mCRC crosstalk, and suggest inhibition of the LRG1-HER3 signaling axis as potential therapeutic strategy for treating patients with mCRC.
Treatment of cefixime-containing wastewater using ultrasound, H2O2, and sodium persulfate and antimicrobial analysis
Authors: Patel Sarvesh , Sharma Jyoti , Gole Vitthal L , Yadav Rajesh K. 
Published: November 2023

Abstract

The present work investigated the degradation of cefixime (C16H15N5O7S2) using a synergy of sonochemical effects with oxidant radical promoters such as hydrogen peroxide and sodium persulfate. Complex hydrocarbon chain of cefixime degraded using different approaches viz, ultrasound + H2O2 (USH), ultrasound + sodium persulfate (USSP), and combined approach ultrasound + H2O2 + persulfate (USHSP). The optimum oxidant dosing was found to be 1:40, 1:50, and 1:20, and the percentage degradation was 74.2, 65.9, and 74.9 for USH, USSP, and USHSP, respectively. The degradation results are also supported by kinetic rate analysis. The maximum kinetic rate constant was observed for USHSP compared to USP and USSP. The time required for degradation using USHSP was half compared to other combinations. The pseudo-first-order kinetic rate constant for USP, USSP, and USHSP was 4.32, 5.32, and 8.40 min-1. The effect of USSP was marginally higher compared to USH and USHSP but the oxidant produced was useful for complete mineralization of cefixime. Total organic carbon removal was 53.2, 83.2, and 79.1% for USP, USSP and USHSP, respectively. Antimicrobial analysis of the treated sample confirmed the degradation results and maximum survival of E. Coli. the strain was found in USH, USSP, and USHSP.
Genetic determinants of COVID-19 vaccine antibody response and breakthrough infection risk: genome-wide association studies based on UK biobank data
Authors: Prieto-Alhambra Daniel , Herraiz Marta Alcalde , Català Martí , Prats-Uribe Albert , Paredes Roger , Xie Junqing 
Published: November 2023

Abstract

Understanding the genetic basis of COVID-19 vaccine immune response is crucial to study the role of genetics on vaccine effectiveness. In our study, we used UK Biobank data to find the genetic determinants of COVID-19 vaccine-induced immunity and breakthrough infections. We conducted four genome-wide association studies among vaccinated participants for COVID-19 vaccine antibody responses and breakthrough susceptibility and severity. Our findings confirmed a link between the HLA region and humoral response after the first and second doses. Additionally, we identified 6 genomic regions associated with breakthrough infection (SLC6A20, ST6GAL1, MXI1, MUC16, FUT6, FUT2) and one with breakthrough severity (AC024590.1-RP11-481E4.1). We also observed that FUT2 genetic loci colocalise with one-dose vaccine response and susceptibility to breakthrough infection, suggesting a potential shared genomic root of these two traits. This study provides novel evidence that genetic variants influence vaccine response and the risk of breakthrough COVID-19 outcomes in the vaccinated population.
Cationic peptides erase memories by removing synaptic AMPA receptors through endophilin-mediated endocytosis
Authors: Beier Kevin , Stokes Eric , Zhuang Yinyin , Toledano Michael , Vasquez Jose , Azouz Ghalia , Hui May , Tyler Isabella , Shi Xiaoyu , Aoto Jason 
Published: November 2023

Abstract

Administration of the Zeta Inhibitory Peptide (ZIP) interferes with memory maintenance and long-term potentiation (LTP). However, mice lacking its putative target, the protein kinase PKMz, exhibit normal learning and memory as well as LTP, making ZIP’s mechanism unclear. Here, we show that ZIP disrupts LTP by removing surface AMPA receptors through its cationic charge alone. This effect was fully blocked by drugs that block macropinocytosis and is dependent on endophilin A2 (endoA2)-mediated endocytosis. ZIP and other cationic peptides selectively removed newly inserted AMPAR nanoclusters, providing a mechanism by which these peptides erase memories without effects on basal synaptic function. Lastly, cationic peptides can be administered locally and/or systemically and can be combined with local microinjection of macropinocytosis inhibitors to modulate memories on local and brain-wide scales. Our findings have critical implications for an entire field of memory mechanisms and highlight a previously unappreciated mechanism by which memories can be lost.
An approach to increase sustainability in agricultural systems; An agroecological analysis of the wheat and sugar beet ecosystems
Authors: Banhangi Fatemeh Moallem , Khorramdel Soroor , Moghaddam Parviz Rezvani , Mahallati Mehdi Nassiri 
Published: November 2023

Abstract

The goal of this study was to undertake a detailed investigation of the agroecological state of the wheat and sugar beet ecosystems on a local scale. From 2001 to 2016, a set of the most critical agroecological indicators of wheat and sugar beet farming systems in the Torbat-e Heydarieh region, northeast of Iran, were studied. Potential yield calculations using both FAO and modified FAO methodologies revealed that potential yield was nearly consistent for both ecosystems over the research period in the region. The extent of the yield gap for both habitats decreased. The study of the regional yield factor revealed that improving the management system resulted in higher actual yield and thus a smaller yield gap in both ecosystems. In both ecosystems, there was a reduction in yield stability. The rate of nitrogen uptake efficiency, nitrogen utilization efficiency, and nitrogen use efficiency (NUE) all decreased during the studied years in the region. According to the findings, the primary cause of the increase in nitrogen consumption, growing intensification, and decreasing stability in the analyzed systems appears to be a deficiency of NUE and its downward trend. As a result, planning and altering management methods focusing on enhancing NUE may be proposed as the first step toward boosting sustainability in the Torbat-e Heydarieh wheat and sugar beet agroecosystems.
Trans-boundary Spatio-Temporal Analysis of Sentinel 5P Tropospheric Nitrogen Dioxide and Total Carbon Monoxide Columns over Punjab &amp; Haryana Regions with COVID-19 Lockdown Impact
Authors: Shabbir Yasir , Guanhua Zhou , ur-Rehman Obaid , Shah Syed Roshaan Ali , Ishaq Rana AhmadFaraz 
Published: November 2023

Abstract
A spatio-temporal analysis of Tropospheric Nitrogen Dioxide (NO2) and Total Carbon Monoxide (CO) concentrations over the Punjab and Haryana regions of India and Pakistan is performed, utilizing datasets from the Sentinel 5-Precursor (S5P). These regions, marked by diverse economic growth factors such as population expansion, power generation, transportation, and agricultural practices, confront similar challenges in atmospheric pollution. This is particularly evident in major urban centers like Delhi and Lahore, which are identified as pollution hotspots. The study also spotlights pollution associated with power plants. In urban areas, Tropospheric NO2 levels are predominantly elevated due to vehicular emissions, whereas residential activities mainly contribute to CO pollution. However, precisely attributing urban CO sources is complex due to its longer atmospheric residence time and intricate circulation patterns. Notably, the burning of rice crop residue in November significantly exacerbates winter pollution episodes and smog, showing a more pronounced correlation with Total CO than with Tropospheric NO2 levels. The temporal analysis indicates that the months from October to December witness peak pollution, contrasted with the relatively cleaner period during the monsoon months of July to September. The severe pollution in the OND quarter is attributed to factors such as variations in boundary layer height and depletion of OH radicals. Furthermore, the study highlights the positive impact of the COVID-19 lockdown on air quality, with a significant decrease in NO2 concentrations during April 2020 (Delhi: 59%, Lahore: 58%). However, the reduction in Total CO columns was less significant. The study also correlates lockdown stringency with Tropospheric NO2 Columns (R2: 0.37 for Delhi, 0.25 for Lahore, 0.22 for Rawalpindi/Islamabad), acknowledging the influence of various meteorological and atmospheric variables.