bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring associations between social media addiction, social media fatigue, fear of missing out and sleep quality among university students: A cross-section study
Authors: Zhu Xinhong , Zheng Taoyun , Ding Linlin , Zhang Xiaona , Li Zhihan , Jiang Hao 
Published: October 2023

Background
Social media use has been linked to poor sleep outcomes among university students in the cyber age, but the association between the negative consequences of social media use and sleep problems is not yet well understood. The present study investigated the relationships among social media usage, social media fatigue (SMF), fear of missing out (FoMO), social media addiction (SMA) and sleep quality in university students.

Method
An online survey was administered to 2744 respondents that included the Pittsburgh Sleep Quality Index (PSQI); questionnaires evaluating FoMO, SMF, and SMA; and questions regarding sleep duration, social media use, health status, and demographic information.

Result
A total of 19.9% of respondents suffered from sleep disturbance. A total of 15.6% of participants had sleep durations less than 5 h, and 21.6% of subjects had sleep durations longer than 9 h. Sleep quality was positively associated with SMF (OR = 1.387, 95% CI: 1.103~1.743), and SMA (OR = 1.415, 95% CI: 1.118~1.791). The relationship between FoMO and sleep disturbance was not significant. Compared to a sleep duration > 9 h, SMF increased the risk of shorter sleep durations [5–6 h sleep (OR = 2.226, 95% CI: 1.132~4.375), 6–7 h sleep (OR = 1.458, 95% CI: 1.061~2.002), and 7–8 h sleep (OR = 1.296, 95% CI: 1.007~1.670)]. FoMO and SMA did not significantly affect sleep duration. In addition, SMA (OR = 3.775, 95% CI: 3.141~4.537), FoMO (OR = 3.301, 95% CI: 2.753~3.958), and sleep disorders (OR = 1.284, 95% CI: 1.006~1.638) increased SMF.

Conclusion
Upon experiencing negative consequences of social media use, such as SMF and SMA, university students were likely to experience sleep problems. Further research exploring the interventions that improve sleep and alleviate negative consequences of social media use should be conducted.
Epidemiology of substance use and mental health disorders among forced migrants displaced from the MENAT region: A systematic review and meta-analysis protocol
Authors: Kazemitabar Maryam , Nyhan Kate , Makableh Natalie , Minahan-Rowley Rebecca , Ali Malak , Wazaify Mayyada , Tetrault Jeanette , Khoshnood Kaveh 
Published: October 2023

Background
Understanding the epidemiology of substance use disorders (SUDs) and mental health disorders (MHDs) among forced migrants from the Middle East and North Africa and Türkiye (MENAT) region is of utmost importance given their distinct challenges and vulnerabilities. Existing research on the topic is substantial; however, comprehensive systematic reviews are limited. We aim to conduct a systematic literature review to bridge this gap, providing a thorough understanding of SUDs and MHDs epidemiology among this population.

Methods
The systematic review will include original, peer-reviewed research articles published in English or Arabic between 2013 and 2023. It will encompass qualitative, quantitative, and mixed-methods studies focusing on SUDs and/or MHDs among forced migrants from the MENAT region. A Medline (via Ovid) search strategy was developed and will be translated into databases of EMBASE (via Ovid), Web of Science Core Collection (as licensed at Yale), and CINAHL. Risk of Bias in the included studies will be assessed using the Joanna Briggs Institute (JBI) checklist for observational studies and the Cochrane Risk of Bias (ROB) 2 tool for intervention studies. Meta-analysis using random-effects models will be conducted and subgroup analyses based on studies’ data will be performed. The systematic review will be conducted based on the framework introduced by the Joanna Briggs Institute. Additionally, the PRISMA-P extension for systematic reviews was used to report the present protocol. The present systematic review protocol has been registered with PROSPERO, an international prospective register of systematic reviews. The review’s registration ID is CRD42021286882.

Discussion
The systematic review aims to explore, identify and synthesize the evidence to reveal the epidemiology of SU and/or MH of forced migrants of the MENAT region as described in this protocol. In sum, the review will provide evidence to fill the gap in the literature and help the stakeholders, policymakers, and health providers to expand current knowledge of the prevalence and risk factors of SU and/or MH in humanitarian settings.
Maternal and Neonatal Outcomes in Vedolizumab- and Ustekinumab-Exposed Pregnancies: Results From the PIANO Registry
Authors: Chugh Rishika , Long Millie D. , Jiang Yue , Weaver Kimberly N. , Beaulieu Dawn B. , Scherl Ellen J. , Mahadevan Uma 
Published: October 2023

Background:
Pregnancy outcomes in patients with inflammatory bowel disease with quiescent disease are similar to those in the general population. Data from the Pregnancy Inflammatory bowel disease And Neonatal Outcomes registry have demonstrated the safety of antitumor necrosis factor (TNF) α agents and thiopurines in pregnancy. The objective of this study was to provide information from the Pregnancy Inflammatory bowel disease And Neonatal Outcomes registry on maternal and fetal outcomes in patients exposed to the newer biologics ustekinumab (UST) and vedolizumab (VDZ).

Methods:
In this multicenter prospective observational study, we included pregnant women with singleton pregnancies and a diagnosis of inflammatory bowel disease. Questionnaires were administered to women at study intake, each subsequent trimester, delivery, and 4, 9, and 12 months after birth. Bivariate analyses were used to determine the independent effects of specific drug classes on outcomes. The exposure cohorts were VDZ, UST, anti-TNF, immunomodulators, and combination with anti-TNF and immunomodulators. All were compared with no exposure and with biologics/immunomodulators.

Results:
There were 1,669 completed pregnancies with 1,610 live births. The maternal mean age was 32.1 (SD 4.6) years at delivery with 66 VDZ exposed and 47 UST exposed. Women on UST were more likely to have Crohn's disease. There was no increased risk of spontaneous abortion, small for gestational age, low birth weight, neonatal intensive care unit stay, congenital malformations, or intrauterine growth restriction with in utero VDZ or UST exposure. The rate of preterm birth was lower (0.0%) for the UST-exposed cohort when compared with other cohorts including VDZ (13.8%), anti-TNF (8.2%), combination therapy (14.2%), immunomodulators (12.3%), and unexposed (9.7%) (P = 0.03). Rates of serious infections at birth, 4 months, and within the first 12 months of life were comparable among all cohorts. Nonserious infections were lower at 12 months in UST-exposed pregnancies. There was no increased risk signal for placental complications in the VDZ cohort. UST infant concentrations at birth were increased whereas VDZ concentrations were overall decreased compared with maternal serum drug concentration.

DISCUSSION:
This analysis of UST and VDZ exposure during pregnancy suggests no increase in complications compared with TNF, immunomodulators, and combination TNF/immunomodulators. No signal was found for increased placental events with either therapy. Continuation of UST and VDZ throughout pregnancy is recommended.
The Sigmoid Colon as an Unusual Primary Site of T Cell Lymphoma in a Patient Presenting With Brain Metastasis
Authors: Bourmaf Mohammad , Motwani Kiran K. , McCool Isaac , Singh Zeba , Kallen Michael , Koka Madhurima , Wong Uni 
Published: October 2023

ABSTRACT
Intestinal T-cell lymphomas are an uncommon type of gastrointestinal malignancy, primarily found in the stomach and small bowel. The liver represents the most common distant organ for metastasis in gastrointestinal malignancies, followed by the lungs. Brain and muscular metastases are rare. We present intestinal T-cell lymphoma with a primary site in the sigmoid colon and metastasis to the brain, meninges, and psoas muscle. Biopsy of the malignant mass confirmed intestinal T-cell lymphoma. To our knowledge, this is the first colon T-cell lymphoma with primary brain and meningeal metastasis with another uncommon site of muscular metastasis.
Asymptotic behavior of solutions of a second-order nonlinear discrete equation of Emden-Fowler type
Authors: Diblík Josef , Korobko Evgeniya 
Published: October 2023

Abstract
The article investigates a second-order nonlinear difference equation of Emden-Fowler type

Δ

2

u

(

k

)

±

k

α

u

m

(

k

)

=
0
,

{\Delta }^{2}u\left(k)\pm {k}^{\alpha }{u}^{m}\left(k)=0,

where

k

k

is the independent variable with values

k
=

k

0

,

k

0

+
1
,

…

k={k}_{0},{k}_{0}+1,\ldots \hspace{0.33em}

,

u
:

{

k

0

,

k

0

+
1
,

…

}

→
R

u:\left\{{k}_{0},{k}_{0}+1,\ldots \hspace{0.33em}\right\}\to {\mathbb{R}}

is the dependent variable,

k

0

{k}_{0}

is a fixed integer, and

Δ

2

u

(

k

)

{\Delta }^{2}u\left(k)

is its second-order forward difference. New conditions with respect to parameters

α
∈
R

\alpha \in {\mathbb{R}}

and

m
∈
R

m\in {\mathbb{R}}

,

m
≠
1

m\ne 1

, are found such that the equation admits a solution asymptotically represented by a power function that is asymptotically equivalent to the exact solution of the nonlinear second-order differential Emden-Fowler equation

y

″

(

x

)

±

x

α

y

m

(

x

)

=
0
.

{y}^{^{\prime\prime} }\left(x)\pm {x}^{\alpha }{y}^{m}\left(x)=0.

Two-term asymptotic representations are given not only for the solution itself but also for its first- and second-order forward differences as well. Previously known results are discussed, and illustrative examples are considered.
Predicting pediatric Crohn's disease based on six mRNA-constructed risk signature using comprehensive bioinformatic approaches
Authors: Zhan Yuanyuan , Jin Quan , Yousif Tagwa Yousif Elsayed , Soni Mukesh , Ren Yuping , Liu Shengxuan 
Published: October 2023

Abstract
Crohn’s disease (CD) is a recurrent, chronic inflammatory condition of the gastrointestinal tract which is a clinical subtype of inflammatory bowel disease for which timely and non-invasive diagnosis in children remains a challenge. A novel predictive risk signature for pediatric CD diagnosis was constructed from bioinformatics analysis of six mRNAs, adenomatosis polyposis downregulated 1 (APCDD1), complement component 1r, mitogen-activated protein kinase kinase kinase kinase 5 (MAP3K5), lysophosphatidylcholine acyltransferase 1, sphingomyelin synthase 1 and transmembrane protein 184B, and validated using samples. Statistical evaluation was performed by support vector machine learning, weighted gene co-expression network analysis, differentially expressed genes and pathological assessment. Hematoxylin–eosin staining and immunohistochemistry results showed that APCDD1 was highly expressed in pediatric CD tissues. Evaluation by decision curve analysis and area under the curve indicated good predictive efficacy. Gene Ontology, Kyoto Encyclopedia of Genes and Genomes and gene set enrichment analysis confirmed the involvement of immune and cytokine signaling pathways. A predictive risk signature for pediatric CD is presented which represents a non-invasive supplementary tool for pediatric CD diagnosis.
Real yields and PVSYST simulations: comparative analysis based on four photovoltaic installations at Ibn Tofail University
Authors: Ait Omar Oumaima , EL Fadil Hassan , El Fezazi Nour Eddine , Oumimoun Zakaria , Ait Errouhi Ahmed , Choukai Oumaima 
Published: October 2023

Abstract
Since the PVSYST simulator is the most well-known software among researchers and PV experts, we chose to compare its results to those of the manual method. Thus, the objective of the article was to obtain the degree of similarity between the results of the PVSYST simulation and the manual calculation of the same parameters, based on the study of the photovoltaic systems of the University Ibn Tofail. Those installations are installed in the Faculty of Letters, Science, the Presidency and CFC. The later used in our study, have different parameters. Hence, to collect these parameters and their distinct data we used multiple sources. The datasheets of each components of the PV system contains the parameters that distinguish the devices therefore it was mandatory to look for that information, since it will facilitate our study. The meteorological database PVGIS, was our reference for the temperature and irradiation data. What’s more is the PVSYST software that helps in the simulation of the PV system and thus having a detailed report with massive information. All this collection of data was aiming to help us comparing the results of yields and other parameters by manual calculation versus simulation in PVSYST. Morocco has demonstrated a strong commitment to combat climate change by embracing renewable energy, particularly photovoltaic systems. In this pursuit, universities like Ibn Tofail University (UIT) play a crucial role in addressing climate challenges and developing research solutions for mitigation. UIT actively participates in projects related to environmental protection and sustainable development, contributing to Morocco’s growth and higher education advancement. As part of its efforts, UIT has been involved in implementing sustainable green projects and promoting renewable energy technologies. A specific study at UIT aimed to compare PVSYST simulation results with manual calculations for four PV systems on campus, considering parameters such as orientation, electrical installation, and panel types. The International Energy Agency (IEA) Photovoltaic Systems Program has established standards and a key concept, the yield factor, measuring the net energy production over a facility’s lifetime compared to the energy used for construction, operation, and supply. By evaluating the accuracy and efficiency of PVSYST, researchers sought to advance the use of PV systems and contribute to Morocco’s renewable energy goals. Such research not only aids in the progression of renewable energy technology but also aligns with Morocco’s vision for sustainable development and environmental protection.
Improving the fatigue life of composite by using multiwall carbon nanotubes
Authors: Zwain Ibaa M. H. , Alithari Ali Sadiq 
Published: October 2023

Abstract
The fatigue life of polymer materials like epoxy can be improved by using stiffeners such as carbon fiber and/or adding multiwall carbon nanotubes (MWCNTs). This article studies the effect of adding MWCNTs with different ratios (0.5, 1, and 2 wt%) to epoxy and composite (epoxy + 30% carbon fibers). The experimental results of the fatigue test with fully reversed bending stress (with R = −1) showed a maximum increase of 788% in fatigue life when adding 1 wt% MWCNTs to epoxy, while the maximum improvement ratio reaches 2,500% when adding 1 wt% MWCNTs to composite. The best results of fatigue life improvement were observed for samples with MWCNTs of 1 wt%. The material will be transferred from low cycle fatigue (less than 105 cycles) to high cycle fatigue (more than 105 cycles) by adding 1 wt% of MWCNTs. At the same time, the ratio of MWCNTs of more than 1 wt% (such as 2 wt%) will decrease the fatigue life due to the agglomeration of nanotubes inside the resin and reduce the positive effect of it. These agglomeration points work as a barrier to load transfer and stress concentration points. The numerical model was built to simulate the fatigue test and compare the results with the experimental with a discrepancy value of 7.5%.
Electrical conductivity of salmon muscles – analysis of the influence of muscle position and electrical current direction during ohmic heating
Authors: Guo Wen , Llave Yvan , Fukuoka Mika 
Published: October 2023

Abstract
In this study, the heating penetration in salmon muscle tissue was evaluated during ohmic heating (OH) at 20 kHz. The electrical conductivities (ECs) in five muscle-tissue sections (fat content from 7.85 to 21.15 %) of salmon were measured under different conditions of applied frequency (50 Hz–20 kHz), temperature (5–70 °C), and direction of the electric current (parallel or series) in relation to the muscle arrangement. Significant differences in the ECs of the five sections were found, especially at high frequencies. A lower fat content and the parallel current direction resulted in higher ECs than a higher fat content and the series current direction. Empirical equations were derived to determine the EC values of all five sections of the salmon fillet based on their temperature dependence. The cooking losses after OH processes were low in the order of parallel < series < minced. These results are of potential value for the design of the OH process for salmon-based products.
On the performance of FSO communication system with WDM and MIMO structure under different turbulent atmospheric conditions
Authors: Tantawy Zeinab H. , El Mashade Mohamed B. , Emran Ahmed A. , Semeia Abdellatif I. M. 
Published: October 2023

Abstract
Free space optical (FSO) communication link is highly weather dependent as the signal passes through the atmospheric channel. The main impairment is atmospheric turbulence, which introduces fading and breakdown the system performance. The performance of FSO link is evaluated in terms of attenuation and link length under different weather conditions. Taking a step further toward the improvement of FSO communication system, wavelength division multiplexing (WDM) is widely used in optical fiber in order to exploit the capacity of a fiber channel more efficiently. Additionally, multiple input multiple output (MIMO) mechanism represents one of the atmospheric mitigation techniques. Thus, integration of MIMO and WDM will provide astonishing results in FSO communication systems. This paper particularly focuses on analyzing the performance of FSO single input single output (FSO-SISO), FSO-WDM, FSO-MIMO, and FSO-WDM-MIMO systems considering different weather conditions. Performance of the different systems has also been compared in terms of received signal power, the quality factor, the bit error rate, and the maximum separation between the transmitter and the receiver for a given received signal level and for various atmospheric conditions. Our results show that increasing the transmitted power and receiver aperture diameter will improve the performance of the system under heavy fog and dense fog.
Neuronal Population Activity in Macaque Visual Cortices Dynamically Changes through Repeated Fixations in Active Free Viewing
Authors: Yamane Yukako , Ito Junji , Joana Cristian , Fujita Ichiro , Tamura Hiroshi , Maldonado Pedro E. , Doya Kenji , Grün Sonja 
Published: October 2023

AbstractDuring free viewing, we move our eyes and fixate on objects to recognize the visual scene of our surroundings. To investigate the neural representation of objects in this process, we studied individual and population neuronal activity in three different visual regions of the brains of macaque monkeys (Macaca fuscata): the primary and secondary visual cortices (V1, V2) and the inferotemporal cortex (IT). We designed a task where the animal freely selected objects in a stimulus image to fixate on while we examined the relationship between spiking activity, the order of fixations, and the fixated objects. We found that activity changed across repeated fixations on the same object in all three recorded areas, with observed reductions in firing rates. Furthermore, the responses of individual neurons became sparser and more selective with individual objects. The population activity for individual objects also became distinct. These results suggest that visual neurons respond dynamically to repeated input stimuli through a smaller number of spikes, thereby allowing for discrimination between individual objects with smaller energy.
Cognitive Aging and the Primate Basal Forebrain Revisited: Disproportionate GABAergic Vulnerability Revealed
Authors: Bañuelos Cristina , Kittleson Joshua R. , LaNasa Katherine H. , Galiano Christina S. , Roth Stephanie M. , Perez Evelyn J. , Long Jeffrey M. , Roberts Mary T. , Fong Sania , Rapp Peter R. 
Published: October 2023

Basal forebrain (BF) projections to the hippocampus and cortex are anatomically positioned to influence a broad range of cognitive capacities that are known to decline in normal aging, including executive function and memory. Although a long history of research on neurocognitive aging has focused on the role of the cholinergic basal forebrain system, intermingled GABAergic cells are numerically as prominent and well positioned to regulate the activity of their cortical projection targets, including the hippocampus and prefrontal cortex. The effects of aging on noncholinergic BF neurons in primates, however, are largely unknown. In this study, we conducted quantitative morphometric analyses in brains from young adult (6 females, 2 males) and aged (11 females, 5 males) rhesus monkeys (Macaca mulatta) that displayed significant impairment on standard tests that require the prefrontal cortex and hippocampus. Cholinergic (ChAT+) and GABAergic (GAD67+) neurons were quantified through the full rostrocaudal extent of the BF. Total BF immunopositive neuron number (ChAT+plus GAD67+) was significantly lower in aged monkeys compared with young, largely because of fewer GAD67+cells. Additionally, GAD67+neuron volume was greater selectively in aged monkeys without cognitive impairment compared with young monkeys. These findings indicate that the GABAergic component of the primate BF is disproportionally vulnerable to aging, implying a loss of inhibitory drive to cortical circuitry. Moreover, adaptive reorganization of the GABAergic circuitry may contribute to successful neurocognitive outcomes.SIGNIFICANCE STATEMENTA long history of research has confirmed the role of the basal forebrain in cognitive aging. The majority of that work has focused on BF cholinergic neurons that innervate the cortical mantle. Codistributed BF GABAergic populations are also well positioned to influence cognitive function, yet little is known about this prominent neuronal population in the aged brain. In this unprecedented quantitative comparison of both cholinergic and GABAergic BF neurons in young and aged rhesus macaques, we found that neuron number is significantly reduced in the aged BF compared with young, and that this reduction is disproportionately because of a loss of GABAergic neurons. Together, our findings encourage a new perspective on the functional organization of the primate BF in neurocognitive aging.