bluuebunny/crossref_metadata_2025_split huggingface dataset:
Modelling and Evaluation of Noise Dispersion from Wind Turbine Operations
Authors: Juodkiene Vytaute 
Published: December 2023

AbstractAll over the world, the need for energy is increasing, and the methods of obtaining it are harmful to the environment. Traditional energy resources are rapidly depleting. During the extraction and burning of fossil fuels, many different pollutants enter the environment. One of the renewable forms of energy is wind energy. Wind energy is mainly used to generate electricity in wind farms. Wind turbines are a unique source of noise because they are installed at a high height above the ground, and the noise emitted is fluctuating and manifests itself in a wide frequency range. Noise from wind turbines as low as 32 dB(A) is a strong nervous system irritant for some people, while noise of 40 dB(A) and above causes severe discomfort for many people [1]. Detailed noise modeling was carried out in the considered area, assessing how noise affects individual dwellings, noise in the living environment of residential buildings were modeled. The noise level without background noise sources of the nearest residential environment was determined by modeling at 31.9 dB(A) during the night, while the limit value for the protection of human health according to HN 33:2011 is 45 dB(A).
Bearing Capacity Analysis of Floating Foundation Model in Homogeneous Very Soft Clay
Authors: Srihandayani Susy , Hakam Abdul , Mera Mas , Ismail Febrin Anas 
Published: December 2023

Abstract
This study focused on the effect of trapped water on the bearing capacity of PVC pipe pile foundations. This research is divided into two models. The first model (pressure cap pipe pole) and the second model (open press pipe pole) each consist of four variations of PVC pipe diameters of 5.08 cm, 6.35 cm, 7.62 cm, and 10.16 cm (standard size PVC pipe diameter) with the same length of 30 cm. In the first type, all pipes are tightly closed at their upper ends. In the second type, all upper-end caps are given two holes, each with a diameter of 0.5 cm. Each pipe pile is alternately piled into soft soil with a moisture content of 98.8% is in a glass box measuring 120 cm x 20 cm x 60 cm. The test results of the load against decrease were analyzed using the Mazurkiwicks interpretation method. The bearing capacity of the end of the pole (Qp) along with the air trapped in the pipe pile (QA) can increase the carrying capacity of important poles compared to the carrying capacity of the pole side (Qs). PVC pipe poles belong to the floating pile foundation group due to the influence of air trapped inside the pile.
The Hygienic Quality of Meat Produced in a Lgeria: Meta-Analysis
Authors: Guergueb Nadjah 
Published: December 2023

Abstract
This meta-analysis aims to provide a comprehensive overview of the hygienic quality of meat in the context of Algerian meat production. A systematic literature search was conducted across various databases, yielding a pool of studies assessing the microbial contamination levels in different types of meat, including: poultry, beef, lamb, camel, sausages, and minced meat, within Algerian slaughterhouses and butcheries. A total of 25 studies met the inclusion criteria, with a combined sample size of 550 meat samples. The selected studies employed standardized methods for microbial enumeration: Total aerobic mesophilic bacteria (TAMB). The collected data were synthesized using random-effects meta-analysis models to estimate the pooled mean bacterial counts, as well as to explore potential sources of heterogeneity. The results of this meta-analysis, revealed considerable variation in bacterial counts across different meat types and sources. The overall pooled, mean bacterial count was 5.15 colony-forming units per gram (CFU.g−1), with significant heterogeneity observed (I² = 87.52 %, P < 0.001). Subgroup analyses indicated that bacterial counts were notably higher in butcher shops, highlighting the need for targeted interventions to improve hygiene practices in these areas. Furthermore, sensitivity analyses were conducted to assess the influence of individual studies on the overall results, and publication bias was evaluated through a funnel plot. In conclusion, this meta-analysis provides valuable insights into the hygienic quality of meat in Algerian meat production, emphasizing the significance of TAMB as an informative indicator. The observed variations in bacterial counts underscored the importance of hygiene practices throughout the meat supply chain, from farm to consumer.
Comparison of NDVI-2 Vaccine EID50 Titre Values After Three Weeks of Freight Under Cold Monitored Storage Condition
Authors: Egbuji Anthony N. , Gyallak James , Mukaila Fatima , Nnabuife Henry E. , Chukwuedo Anthony A. 
Published: December 2023

Abstract
The EID50 titres per dose values of three batches of NDVI-2 were determined as log10 EID50 7.7, 7.6 and 6.8 after production, against reference EID50 5.5 per dose. These values were log10 EID50 2.2, 2.1 and 1.3 above the reference EID50 for NDVI-2. These vaccines were re-evaluated at PANVAC laboratory Debre-Zeit, prior to release. The initial EID50 values were compared with EID50 values obtained by the certifying laboratory, after three weeks of cold monitored freight. The packaged vaccine cold storage temperature of +1.9 oC prior to the shipment, was recorded with the aid of a temperature logger. The temperature logger was set to record and retain packaged vaccine cold storage temperature at hourly intervals during the freight. At the end of three-week freight, the temperature logger readings were analysed, and temperature range of -2.48 oC to 7.7 oC was observed throughout the freight. However, sudden rise in packaged vaccine storage temperature from 7.7 oC to 22.28 oC was noticed on the last day of freight. The initial EID50 titre per dose values, when compared with EID50 log10 6.5, 6.8, and 6.6 per dose obtained by the certifying laboratory after the cold monitored freight and re-evaluation, showed EID50 titre loss of log10 EID50 1.2, 0.8 and 0.6, respectively. The observed EID50 loss could not invalidate these vaccine batches, considering that these had an initial EID50 titre per dose values that were well above the reference EID50 titre for NDVI-2. In Nigeria, and to our knowledge, this is the first recorded monitored cold storage temperature transit for NDVI-2.
Consumption of Cultural Content in the Digital Environment in the Post-Pandemic Latvia
Authors: Budanceva Jelena , Svirina Anna 
Published: December 2023

Abstract

Research purpose. COVID-19 has a huge impact on the life-style in modern society, including the switching to online studies and remote work. The majority of the studies view the consequences as negative, while at the same time the pandemic have enhanced some positive changes. The goal of the research is to find out, how the time spent online and the content consumed online are changed due to pandemic as well as to determine what cultural content young people are consuming online.

Design / Methodology / Approach. To achieve the research purpose author conducted a survey, using own developed instrument – questionnaire. In total, 1029 respondents participated and 934 questionnaires were valid. The survey was conducted in December 2020 using snowball sampling. The developed questionnaire contained 14 questions were grouped into 2 sections: A) Questions about consumption on cultural content online before and during the pandemic and B) Respondent profile.

Findings. Totally the number of hours young people are spending online in post-pandemic period increased because of COVID, but most fastest growth is by those who spent more than 8 hours (from 15 to 100 persons). 53,2% from all respondents are spending about ¼ of all time online consuming cultural content, and 23,2% are not consummating cultural content online at all. 3 main significant reasons why the youth is spending time online are: it is easy and fast (77%); the digital environment is always along in the phone (77%); in the digital environment it is possible to communicate with friends (65%). Spending time online most respondents are consuming informative content, including news and blogs (64%) and the content related to hobbies or leisure (60%), but the cultural content was ranked with just 26%. The most used digital cultural content is movie watching (30,5%), seminars and courses about culture (18,6%), conferences dedicated to culture topics (17,1%), tours in world museums (16,3%) and study books (15,9%). Further, gender, like gender, can not be considered both a significant factor and a predictor of digital consumption. Unlike the two, occupation and place of living are predictors for share of online cultural consumption: occupation appeared to be a moderating factor for digital consumption of cultural content, which make Latvian findings different from what appears in literature.

Originality / Value / Practical implications. The results of the research are representing changes in online consumption of culture goods and services caused by COVID-19. As the target group of this survey are youth from 18 to 25 years old, they can be used by evaluating potential and planning of culture goods and services online for this target group. It because evident, that some of the post-pandemic cultural consumption trends appeared as the impact of pandemic, enhancing cultural consumption growth in certain areas, involving more youngsters to cultural consumption compared to pre-pandemic period.
A pan-cancer analysis of the oncogenic role of Golgi transport 1B in human tumors
Authors: Tian Bo , Pang Yanan , Gao Ye , Meng Qianqian , Xin Lei , Sun Chang , Tang Xin , Wang Yilin , Li Zhaoshen , Lin Han , Wang Luowei 
Published: December 2023

Abstract

Background
Owing to the aggressiveness and treatment-refractory nature of cancer, ideal candidates for early diagnosis and treatment are needed. Golgi transport 1B (GOLT1B) has been associated with cellular malignant behaviors and immune responses in colorectal and lung cancer, but a systematic pan-cancer analysis on GOLT1B has not been conducted.

Methods
The expression status and clinical association of GOLT1B in The Cancer Genome Atlas (TCGA) were analyzed. Genetic and methylation alterations in GOLT1B were explored. The relationship between GOLT1B and immune cell infiltration was also investigated. Genes related to GOLT1B expression were selected and analyzed.

Results

GOLT1B was highly expressed in most tumors, and there was a positive correlation between GOLT1B expression and clinical pathological parameters. High expression levels of GOLT1B have been associated with poor prognosis of most cancers. Copy number amplification was the primary type of GOLT1B genetic alterations, which was related to the prognosis of pan-cancer cases. There were different levels of GOLT1B promoter methylation across cancer types. The methylation level of the probe cg07371838 and cg25816357 was closely associated with prognosis in diverse cancers. There was also a positive correlation between GOLT1B genetic alterations and CD4+ T lymphocytes, especially the Th2 subset, as well as between GOLT1B expression and the estimated infiltration value of cancer-associated fibroblasts. Serine/threonine kinase receptor-associated protein (STRAP), integrator complex subunit 13 (INTS13), and ethanolamine kinase 1 (ETNK1) were the most relevant genes for GOLT1B expression, and their interactions with GOLT1B were involved in regulating the transforming growth factor (TGF)-β receptor signaling pathway and epithelial-mesenchymal transition (EMT).

Conclusions
This pan-cancer analysis provided a comprehensive understanding of the oncogenic role of GOLT1B, highlighting a potential mechanism whereby GOLT1B influences the tumor microenvironment, as well as cancer immunotherapy.
Autophagy-dependent ferroptosis in infectious disease
Authors: Li Jiarou , Wang Hongliang 
Published: December 2023

Abstract
Autophagy is the initial defense response of the host against pathogens. Autophagy can be either non-selective or selective. It selectively targets the degradation of autophagic substrates through the sorting and transportation of autophagic receptor proteins. However, excessive autophagy activity will trigger cell death especially ferroptosis, which was characterized by the accumulation of lipid peroxide and free iron. Several certain types of selective autophagy degrade antioxidant systems and ferritin. Here, we summarized the latest researches of autophagy in infection and discuss the regulatory mechanisms and signaling pathways of autophagy-dependent ferroptosis.
Crosstalk between gut microbiota and gut resident macrophages in inflammatory bowel disease
Authors: Zhang Haohao , Wang Xueying , Zhang Jing , He Yixuan , Yang Xiumin , Nie Yongzhan , Sun Lijuan 
Published: December 2023

Abstract
Macrophages residing in the gut maintain gut homeostasis by orchestrating patho-gens and innocuous antigens. A disturbance in macrophages leads to gut inflamma-tion, causing conditions such as inflammatory bowel disease (IBD). Macrophages ex-hibit remarkable plasticity, as they are sensitive to various signals in the tissue micro-environment. During the recent decades, gut microbiota has been highlighted refer-ring to their critical roles in immunity response. Microbiome-derived metabolites and products can interact with macrophages to participate in the progression of IBD. In this review, we describe recent findings in this field and provide an overview of the current understanding of microbiota-macrophages interactions in IBD, which may lead to the development of new targets and treatment options for patients with IBD.
Digitaler Euro: hohe Kosten bei nicht erkennbaren Vorteilen
Authors: Bofinger Peter 
Published: December 2023

Abstract
The ECB has embarked on an uncertain path with the digital euro project. It is pursuing a strategy that is unclear about what problems it is trying to solve and what specific goals it is trying to achieve. The ECB has not yet been able to diagnose a clear market failure that would justify such far-reaching government intervention. The attempt to claim the need for a “monetary anchor” instead is not very convincing. The current design is unlikely to attract much interest from citizens and thus will not contribute to greater European strategic autonomy in the payment system. This requires a solution that does not rely on system-specific balances and is therefore more convenient, while simultaneously avoiding impending risks to the financial system.
Digitales Zentralbankgeld: Dabei sein ist nicht alles
Authors: Schäfer Stefan 
Published: December 2023

Abstract
The European Central Bank (ECB) wants to push ahead with the “digital euro” project. However, the digital euro is by no means the only and possibly not even a good (let alone the best) way to respond to the comprehensive change in the world of money. In terms of its reputation, the ECB must act with the utmost caution. Instead of launching its own project on the market in just a few years, the ECB would be well advised to take a step back and support a competition of ideas that is open to all technologies.
Claudia Goldin revolutioniert Wissen um Frauen im Arbeitsmarkt
Authors: Gathmann Christina , Sierminska Eva 
Published: December 2023

Abstract
This year’s Nobel Prize in Economics goes to Claudia Goldin from Harvard University. She is a labour economist as much as an economic historian, and only the third woman to receive the Nobel Prize in Economics. Goldin revolutionised our knowledge and understanding of women’s educational and occupational choices, their labour market careers and the family obligations they have faced over the centuries. Her work is extremely broad, spanning from historical studies of girls’ educational choices in the 19th century to the determinants of the gender pay gap in the 21st century. Her work sheds light on important economic and social developments that many have been overlooked. She identifies patterns and relationships that were previously hidden or unknown, and shows novel causal mechanisms for long-run changes that are di˚cult to identify empirically.
Von der Krisenreserve zur Agrarreserve – falsche Anreize im neuen Rechtsrahmen?
Authors: Kranen Dirk H. , Röpcke Iris , Weyel Jan-Eric 
Published: December 2023

Abstract
The European Union’s new Agricultural Crisis Reserve, introduced in 2023, aims at enhancing support for the agricultural sector during market crises. Unlike its predecessor, this reserve is funded directly from the EU budget, eliminating the need to cut direct payments to farmers. However, this change has unintentionally created an incentive for member states to trigger the reserve more frequently, depleting its resources rapidly. This article explores how this shift has led to a “Tragedy of the Commons” scenario, where member states seek individual advantages at the expense of the collective interest.
Entgelttransparenzgesetz erreicht Ziel nicht
Authors: Brändle Tobias , Koch Andreas 
Published: December 2023

Abstract
The German Pay Transparency Act (Entgelttransparenzgesetz) is intended to help enforce the principle of equal pay for women and men doing equal work or work of equal value. After the second evaluation, it is clear that this is not being achieved with the existing instruments of the law. Without major changes, the law remains largely ineffective - while at the same time imposing substantial bureaucratic requirements on firms. This article describes the results of the second evaluation and shows possible reforms.
Subventionen in Zeiten knapper Kassen
Authors: Laaser Claus-Friedrich , Rosenschon Astrid , Schrader Klaus 
Published: December 2023

Abstract
The decision of the Federal Constitutional Court to classify the transfer of €60 billion in unused coronavirus loan authorisations to the Climate and Transformation Fund as unconstitutional has plunged fiscal policy in Germany into a crisis. A “cash audit” is therefore called for. This article draws on the findings of the Kiel Subsidy Report. According to the budget plans for 2022 and 2023, federal financial aid is set to increase sharply. In 2023, they are expected to be even higher than the federal government’s social spending. Financial aid should therefore not be left out in order to counter-finance budget gaps.
Perbedaan Kadar Kreatinin Serum Pada Pasien Preeklamsia Berat Early dan Late Onset RSUP Dr. M. Djamil Padang tahun 2021
Authors: Juliani Rifa , Basyir Vaulinne , Reza Mohamad , Ariadi Ariadi , Rofinda Zelly Dia 
Published: December 2023

Latar Belakang: Preeklamsia merupakan salah satu faktor risiko penyebab tingginya angka kematian saat masa kehamilan dan nifas. Preeklamsia akan menyebabkan kerusakan banyak organ, salah satunya organ ginjal. Salah satu pemeriksaan yang dilakukan untuk mengevaluasi fungsi ginjal adalah pemeriksaan kreatinin.
Objektif: Penelitian ini bertujuan untuk membandingkan rata-rata kadar kreatinin serum antara pasien dengan preeklamsia berat early onset danlate onset di RSUP DR. M. Djamil Padang.
Metode: Penelitian ini adalah penelitian analitik observasional dengan menggunakan pendekatan cross sectional. Penelitian ini dilakukan di rekam medis RSUP Dr. M. Djamil Padang pada bulan Juni 2022 – Juli 2022 dengan jumlah sampel sebanyak 36 pasien preeklamsia berat early onset dan 36 pasien preeklamsia berat late onset.
Hasil: Hasil analisis bivariat memperlihatkan perbedaan yang signifikan antara kreatinin serum preeklamsia berat early onset dan late onsetdengan uji Mann-Whitney (0,8; 0,7, p=0.023). Kreatinin serum dan indeks massa tubuh ditemukan berkorelasi secara signifikan dengan uji sperman (r=-,0325, p=0.005) dan tidak ditemukan korelasi yang signifikan antara kreatinin serum dengan usia (r= -0,062, p=0.060), tekanan darah sistolik (r=0,152, p=0.020), dan diastolik (r=0,061, p=0.060).
Kesimpulan: preeklamsia berat early onset memiliki rata-rata kreatinin serum yang lebih tinggi daripada preeklamsia berat late onset, dan adanya korelasi yang signifikan antara kreatinin serum dan indeks massa tubuh.
Kata kunci: Preeklamsia berat, kreatinin serum, usia, tekanan darah, indeks massa tubuh
Dehydration: Need For an Improved Rehydrating Energy Drink
Authors: Faruqui Arif A. 
Published: December 2023

Oral rehydration therapy (ORT) is the cornerstone treatment for managing dehydration. However, ORT cannot “halt” the underlying intestinal fluid loss, a significant mechanism of infectious organisms responsible for causing diarrhea. Reports have demonstrated the role of calcium in treating contagious diarrhea through the calcium-sensing receptor (CaSR), which is absent in oral rehydration solution (ORS). CaSR is a novel target that has demonstrated its effectiveness in treating diarrhea. CaSR is activated by a simple calcium agonist, an easily accessible, inexpensive, and safe-to-use option in the pediatric population. Adding nutrients would be simple and may increase the efficacy of the current ORS treatment. Maltodextrin (MDs) over glucose in ORS has shown benefits in these patients as the osmolality of MDs is significantly lower than that of disaccharide sugars. Thus, adding multivitamins, nutrients, and energy boosters to WHO- ORS may improve the efficacy of ORS in treating diarrhea, reducing malnutrition, and providing energy to curb fatigue.
Hubungan Nilai Cycle Threshold dengan Derajat dan Outcome Pasien COVID-19 Komorbid Hipertensi
Authors: Wahyuni Indah Sri , Indra Beni , Masnadi Nice Rachmawati 
Published: December 2023

Latar Belakang: Hipertensi merupakan komorbid utama pada pasien COVID-19. Pasien dengan komorbid hipertensi memiliki faktor risiko kematian lebih tinggi dibandingkan dengan pasien tanpa hipertensi. Pasien COVID-19 dengan hipertensi cenderung memiliki viral load yang lebih tinggi, dengan demikian akan didapatkan hasil nilai CT yang rendah dari pemeriksaan RT-PCR.
Objektif: Mengetahui hubungan nilai CT dengan derajat penyakit COVID-19 dan luaran klinis pada pasien dewasa dengan komorbid hipertensi yang terkonfirmasi positif COVID-19 di RSUP Dr. M. Djamil Padang tahun 2021.
Metode: Jenis penelitian ini adalah analitik cross-sectional study dengan menggunakan data sekunder yang diperoleh dari rekam medik pada bulan Mei 2022-Juni 2022. Sampel mencakup semua pasien dewasa dengan komorbid hipertensi yang terkonfirmasi positif COVID-19 yang memenuhi kriteria inklusi dan eksklusi.
Hasil: Terdapat 153 pasien yang memenuhi kriteria inklusi dan eksklusi dalam penelitian ini. Sebagian besar pasien berusia ≥60 tahun (60,8%), berjenis kelamin laki-laki (58,8%), menderita hipertensi derajat 2 (52,9%), memiliki riwayat hipertensi >5 tahun (62,7%), terkonfirmasi COVID-19 derajat berat-kritis (54,2%), dengan luaran klinis pasien meninggal (54,2%). Hasil analisis didapatkan masing-masing p=0,001 untuk hubungan nilai CT dengan derajat penyakit COVID-19 dan luaran klinis.
Kesimpulan: Terdapat hubungan yang signifikan antara nilai CT dengan derajat penyakit COVID-19 dan luaran klinis pada pasien dewasa dengan komorbid hipertensi yang terkonfirmasi positif COVID-19.
Kata kunci: COVID-19, hipertensi, cycle threshold (CT).