bluuebunny/crossref_metadata_2025_split huggingface dataset:
Life cycle assessment of hemp-based milk alternative production in Lower Saxony, Germany, based on a material flow analysis of a pilot scale
Authors: Ferdouse Jannatul , Silva Beatriz Q. , Baune Marie-Christin , Terjung Nino , Smetana Sergiy 
Published: January 2024

Abstract
Purpose
Recently, demand for plant-based milk products (PBMP) has increased for multiple reasons, such as the rapid population growth expected to reach 9.7 billion by 2050, health concerns such as lactose intolerance, nutritional aspects, ethical reasons, and environmental concerns. This leads to increased demand for food and competition for natural resources. Hemp-based milk is an emerging dairy alternative, and stakeholders in the supply chain are becoming increasingly interested in learning about the environmental effects of its production. This article aims for a comparative life cycle assessment of hemp-based and bovine milk with fat and protein correction to account for the differences in macronutrient content.

Methods
The cradle-to-factory gate LCA relied on experimental cultivation and milk production in Lower Saxony, Germany. Inventory was based on primary data from fields and the pilot plant of DIL e. V. and on literature and ecoinvent database to develop a life cycle assessment (LCA) model. The LCA was performed using Simapro 9.3 software and IMPACT 2002+ impact assessment method. The life cycle stages include cultivation, harvesting, and milk production. The study compared hemp-based milk to bovine milk based on 1 kg fat and protein-corrected milk (FPCM) as a functional unit (FU). Co-products are taken into consideration using mass-economic allocation.

Results
The results showed that hemp cultivation accounted for the highest impact (99%) in the production chain of hemp milk production. The GWP of 1 kg of FPCM hemp-based milk is 0.42 kg CO2 eq. The energy consumption for 1 kg of FPCM hemp-based milk is 4.73 MJ (12.26% lower than bovine milk). The other main factors impacting hemp-based milk production were terrestrial ecotoxicity (6.444E2 kg TEG soil) and aquatic ecotoxicity (2.458E2 kg TEG water). Hemp fiber was the co-product with 40% of the allocated impacts. The results are sensitive to the changes in fat-protein contents, functional unit, and system boundaries. The results demonstrated that the impacts of hemp milk production were within the range indicated for other PBMP production and 51.7% lower than bovine milk production in terms of GWP. This range primarily stems from field emissions, fertilizer application, and machinery usage during cultivation and harvest.

Conclusion
The results of the comparisons of bovine milk and hemp-based milk were dependable on the FU. The hemp-based milk has the potential to be a more sustainable alternative to bovine milk due to considerably lower impacts in impact categories—land occupation (99% lower than bovine milk), global warming (52% lower than bovine milk), and ionizing radiation (23% lower than bovine milk). It is primarily due to less use of agricultural machinery, less land requirement, and lower NH3 emissions than bovine milk in various stages of milk production.
Biosynthesis of Zinc Oxide Nanoparticles Using Bacillus paramycoides for In Vitro Biological Activities and In Vivo Assessment Against Hepatorenal Injury Induced by CCl4 in Rats
Authors: El-Refai Heba A. , Saleh Alaa M. , Mohamed Shimaa I. A. , Aboul Naser Asmaa F. , Zaki Rania A. , Gomaa Sanaa K. , Hamed Manal A. 
Published: January 2024

AbstractRecently, impressive developments in the field of nanotechnology have been achieved. The study aimed to synthetize zinc oxide nanoparticles (ZnONPs) from locally isolated terrestrial Bacillus paramycoides (MCCC 1A04098) bacteria and assess its role as antioxidant, antimicrobial, and anticancer agent. The antioxidant activity was done using the percentage of DPPH scavenging method. The antibacterial activity was evaluated against Escherichia coli, Staphylococcus aureus, Bacillus cereus, and Candida albicans. The anti-proliferation assay against hepatocellular carcinoma (HepG2) and human breast cancer (MCF-7) cell lines was estimated by neutral red assay. The apoptotic effect of ZnONP was measured by flow cytometry. The in vivo evaluation was carried out against hepatorenal injuries induced by carbon tetrachloride (CCl4) in rats comparing with silymarin as a reference drug. The oxidative stress markers, liver and kidney function enzyme indices, lipid profile, and the histological features of the liver and kidney were also examined. ZnONPs revealed antioxidant and antibacterial effects. It also exerted cytotoxic and apoptotic effect in a dose dependent manner without any toxicity on normal cell line. ZnONPs improved all the biochemical parameters under investigation to varying degrees, and the histological pictures of the liver and kidney confirmed the results. In conclusion, ZnONPs were successfully synthesized from the terrestrial Bacillus paramycoides and recorded in vitro antioxidant, anticancer, and antibacterial effects as well as in vivo anti-hepatorenal toxicity effects.
Graphical Abstract
Delineation of lineaments for groundwater prospecting in hard rocks: inferences from remote sensing and geophysical data
Authors: Embaby Ashraf , Youssef Youssef M. , Abu El-Magd Sherif Ahmed 
Published: January 2024

AbstractEgypt is grappling with water scarcity challenges, which are exacerbated by extensive urban development in arid coastal regions with rugged terrain. Although desalinated water is an alternative source in the remote Halayeib region of Southeast Egypt, its cost increases reliance on groundwater from the intricate aquifers. This study aims to accurately delineate hydro-structural features, known as lineaments, and assess their impact on the groundwater conditions in this promising region. This integrated approach involves the assessment of various spaceborne sensors, including optical (Landsat 8), Digital Elevation Models (ALOS and ASTER-DEMs), and radar (Sentinel-1), using geospatial and geostatistical techniques within the Geographic Information System (GIS). Radar-based sensors, particularly the Sentinel-1A vertical–vertical (S1A VV) polarization, outperform all other datasets in extracting lineaments, yielding 4883 lineaments that correspond to the regional geological faults. These lineaments trend in NE–SW, NNE–SSW, NW–SE, and E-W directions. The results also indicated that both digital elevation models (DEMs) were less effective, showing different orientations with azimuth angles. S1A VV proved to be highly effective in identifying subsurface fractured hard rock terrains beneath thin sedimentary covers, especially in the flat coastal area of Wadi Serimatai, where they intersected natural drainage pathways. Geoelectrical sections confirmed that there are orthogonal subsurface faults extending from fractured basement aquifers to near-surface layers. These faults align with the NE-SW and NNE-SSW directions observed in S1A VV lineaments. Geostatistical analysis revealed that S1A VV structural lineaments, lithological, and hydrogeological factors influence the occurrence of groundwater. This emphasizes the structural control over groundwater and its significant impact on water flow and storage. The study provides valuable insights for groundwater management, guiding decisions related to the development of groundwater resources.
A Study on Lebanon’s Competitive Knowledge-Based Economy, Relative Strengths, and Shortcomings
Authors: Ben Hassen Tarek 
Published: January 2024

AbstractLebanon faces several social, political, and economic challenges delaying the efforts to develop a sustainable economy and inclusive society. The advancement of the knowledge economy is critical to the future economic prosperity of Lebanon. This paper aims to scrutinize the state of the knowledge-based economy in Lebanon, focusing on five pillars, such as education and human capital, entrepreneurship, innovation system, economic and institutional regime, and information and communications technology (ICT), and to present recommendations for future action. The methodology is based on semi-structured face-to-face and phone interviews with stakeholders using two questionnaires. The paper finds that the process of transitioning towards a knowledge-based economy in Lebanon is influenced by two contrasting factors: the education system and the entrepreneurship culture, on the one hand, and the country’s political turmoil, on the other. Indeed, moving toward a knowledge-based economy in Lebanon is supported by its highly qualified and multilingual human resources, which is an outcome of the reliable educational system and reinforced by a robust entrepreneurial spirit. However, several issues, such as weak ICT infrastructure, incompetent public institutions, and the brain drain, hinder the transition to a knowledge-based economy. These results help clarify and critically analyze the present state of the knowledge-based economy in Lebanon, which has various policy implications.
An Investigation on Hydraulic Aspects of Rectangular Labyrinth Pool and Weir Fishway Using FLOW-3D
Authors: Mirkhorli Parisa , Ghaderi Amir , Alizadeh Sanami Forough , Mohammadi Mirali , Kuriqi Alban , Kisi Ozgur 
Published: January 2024

AbstractTwo different arrangements of the weir (i.e., straight weir and rectangular labyrinth weir) were used to evaluate the effects of geometric parameters such as weir shape, weir spacing, presence of an orifice at the weir, and bed slope on the flow regime and the relationship between discharge and depth, variation and distribution of depth-averaged velocity, turbulence characteristics, and energy dissipation at the fishway. Computational fluid dynamics simulations were performed using FLOW-3D® software to examine the effects on flow conditions. The numerical model was validated by comparing the calculated surface profiles and velocities with experimentally measured values from the literature. The results of the numerical model and experimental data showed that the root-mean-square error and mean absolute percentage error for the surface profiles and normalized velocity profiles of plunging flows were 0.014 m and 3.11%, respectively, confirming the ability of the numerical model to predict the flow characteristics of the pool and weir. A plunging flow can occur at values of L/B = 1.83 (L: distance of the weir, B: width of the channel) and streaming flow at L/B = 0.61 for each model. The rectangular labyrinth weir model has larger dimensionless discharge values (Q+) than the conventional model. For the conventional weir and the rectangular labyrinth weir at submerged flow, Q is proportional to 1.56 and 1.47h, respectively (h: the water depth above the weir). The average depth velocity in the pool of a conventional weir is higher than that of a rectangular labyrinth weir. However, for a given discharge, bed slope, and weir spacing, the turbulent kinetic energy (TKE) and turbulence intensity (TI) values are higher for a rectangular labyrinth weir compared to conventional weir. The conventional weir has lower energy dissipation than the rectangular labyrinth weir. Lower TKE and TI values were observed at the top of the labyrinth weir, at the corner of the wall downstream of the weir, and between the side walls of the weir and the channel wall. As the distance between the weirs and the bottom slope increased, the average depth velocity, the average value of turbulent kinetic energy and the turbulence intensity increased, and the volumetric energy dissipation in the pool decreased. The presence of an opening in the weir increased the average depth velocity and TI values and decreased the range of highest TKE within the pool, resulted in larger resting areas for fish (lower TKE), and decreased the energy dissipation rates in both models.
Preliminary study: cognitive behavioural therapy for insomnia in adolescents with anorexia nervosa
Authors: Crevits Léna , Silva Catarina , Bat-Pitault Flora 
Published: January 2024

Abstract
Purpose
Insomnia and anorexia nervosa (AN) are frequently comorbid, negatively affecting the evolution and the prognosis of AN. Within this framework, the management of sleep disorders appears as critical. The aim of this retrospective study is to assess, for the first time, the efficacy of cognitive and behavioural therapy for insomnia (CBT-I) on sleep disturbances in adolescents with AN. To do so, we investigated the impact of CBT-I on sleep disturbances and sleep-related outcomes, in BMI, AN symptoms, anxiety and depressive symptoms, emotionality and quality of life. These features were compared between two groups of patients with AN, one following CBT-I, and the other receiving the regular treatment at the psychiatric unit.

Methods
Data collection occurred between January and May 2022. The study included 42 adolescents in-treatment at the Eating Disorders care specialised unit at Salvator Hospital in Marseille. They were randomly assigned to the CBT-I group (N = 31) or the control group (N = 11). Several clinical elements were assessed using sleep diaries and self-report questionnaires.

Results
Participants undergoing CBT-I showed a significant improvement in sleep latency, total wake time and sleep efficacy, as well as in physical well-being. No significant effects were found regarding AN symptoms.

Conclusion
These preliminary findings provide support for CBT-I effectiveness in adolescents with AN, as shown by significant improvements in several sleep parameters, as well as in physical well-being. These promising results, underline the relevance of this topic and its potential benefits for a more appropriate treatment for adolescents with AN.
Level of evidence: Level V, retrospective study.
Recent advances in the treatment for gynecologic oncology
Authors: Li Lei , Lang Jinghe 
Published: January 2024

AbstractThis commentary summarized the most important findings in the first half 2023 year based on Society of Gynecologic Oncology (SGO) annual meeting and publications in crucial journals.This commentary provided a comprehensive overview of notable developments in the field of gynecologic oncology throughout the first half of 2023, drawing insights from the Society of Gynecologic Oncology (SGO) Annual Meeting and pivotal publications in esteemed journals. The discourse delved into the forefront of molecular mechanisms, emphasizing critical themes such as homologous recombination repair deficiency, mismatch repair, immune checkpoint blockades, and anti-angiogenesis in various cancers. Specific attention was given to advancements in targeted and immunotherapeutic modalities, notably examining the efficacy and safety profiles of poly (ADP-Ribose) polymerase inhibitors (PARPi) in ovarian cancer. Conclusively, the commentary underscored the transformative impact of molecularly guided therapies, marking them as pivotal in addressing refractory conditions and set the stage for heightened expectations in future advancements.PARP inhibitors have become the standard maintenance treatment for ovarian cancer. Among the first six articles, two (SOLO1 and PAOLA-1) summarized evidence supporting the improvement of overall survival with PARP inhibitors in maintenance therapy, while the NOVA study reported no benefit in overall survival. The first, fourth, and sixth articles discussed the feasibility of PARP inhibitors, immune checkpoint inhibitors used alone or in combination in neoadjuvant therapy (post-chemotherapy surgery). The latter two articles focused on the application of PD-1 (immune checkpoint inhibitors) in locally advanced cervical cancer, demonstrating enhanced efficacy. Currently, immune checkpoint inhibitors are commonly used in advanced cervical and endometrial cancers due to their status as hot tumors. Their use, either alone or in combination with anti-angiogenic drugs, has shown better outcomes in recurrent and advanced refractory endometrial and cervical cancers compared to traditional chemotherapy. A study from Huashan Hospital discussed the effectiveness of immune checkpoint inhibitors combined with anti-angiogenic therapy in recurrent cervical cancer, although there might be a typo as the initial mention was about endometrial cancer. The following article discussed late-stage endometrial cancer, finding no difference in survival between chemotherapy and chemotherapy combined with radiation. Subsequent articles highlighted the superiority of immune checkpoint inhibitors combined with chemotherapy in treating recurrent endometrial cancer, as well as the efficacy of immune checkpoint inhibitors combined with anti-angiogenic therapy in endometrial cancer. The final article focused on the therapeutic effect of HER2-positive ADC class drugs in uterine cancer sarcoma.
Classical Hollywood, American Modernism
Authors: Brower Jordan 
Published: January 2024

Classical Hollywood, American Modernism charts the entwined trajectories of the Hollywood studio system and literary modernism in the United States. By examining the various ways Hollywood's industry practices inflected the imaginations of authors, filmmakers, and studios, Jordan Brower offers a new understanding of twentieth-century American and ultimately world media culture. Synthesizing archival research with innovative theoretical approaches, this book tells the story of the studio system's genesis, international dominance, decline, and continued symbolic relevance during the American postwar era through the literature it influenced. It examines the American film industry's business practices and social conditions, demonstrating how concepts like anticipated adaptation, corporate authorship, systemic development, and global distribution inflected the form of some of the greatest works of prose fiction and nonfiction by modernist writers, such as Anita Loos, F. Scott Fitzgerald, William Faulkner, Patsy Ruth Miller, Nathanael West, Parker Tyler, Malcolm Lowry, and James Baldwin.
Information provision and preferences for more sustainable dairy farming: Choice experimental evidence from Sweden
Authors: Oyinbo Oyakhilomen , Hansson Helena 
Published: January 2024

AbstractDairy farming in Europe faces profound environmental, social, and economic sustainability challenges, which are of significant policy interest. These challenges support the need for a transition toward the uptake of more sustainable dairy farming practices. This paper examines the effects of an advisory instrument “balanced sustainability information” on farmers’ preferences for more grass-based feeding systems using a between-subjects design and a discrete choice experiment among a sample of Swedish dairy farmers. Conceptually, we develop a state-dependent utility framework with Bayesian updating to motivate the impact pathway. Our results demonstrate that on average, balanced sustainability information has negligible effects on farmers’ feed choices, which could be a consequence of opposing responses to the information, among others. Considering farmer heterogeneity based on their identities and prior knowledge, we find support for some evidence of treatment effects. Our findings highlight important and policy-relevant critical reflections about overoptimistic expectations of information provision as an instrument to nudge behavioral change toward more sustainable farming practices.
Fueling SMEs’ product innovation through entrepreneurial passion during COVID-19: The role of dynamic capability and environmental opportunities
Authors: Shi Yongdong , Liu Yu-xiao , Fong Veronica Hoi In , Lan Ya 
Published: January 2024

Abstract
COVID-19 may not only pose threats but also provided opportunities for innovation and growth for many high-tech small- and medium-sized enterprises (SMEs). This study investigates the relationship between entrepreneurial passion (EP), dynamic capability (DC) for innovation and product innovation performance in SMEs during COVID-19. Hierarchical regression and bootstrapping methods were employed per the survey data of 195 Chinese SMEs. The results reveal that EP is an imperative antecedent of DC and product innovation. DC also positively mediates the relationship between SMEs’ product innovation performance and top managers’ EP. In addition, this mediation effect of DC becomes more pronounced when firms are facing more opportunities. These findings advance the existing literature by specifying the process top managers use to cultivate product innovation within SMEs in times of crisis.
FORBIDDEN INDUCED SUBGRAPHS AND THE ŁOŚ–TARSKI THEOREM
Authors: CHEN YIJIA , FLUM JÖRG 
Published: January 2024

AbstractLet
$\mathscr {C}$
be a class of finite and infinite graphs that is closed under induced subgraphs. The well-known Łoś–Tarski Theorem from classical model theory implies that
$\mathscr {C}$
is definable in first-order logic by a sentence
$\varphi $
if and only if
$\mathscr {C}$
has a finite set of forbidden induced finite subgraphs. This result provides a powerful tool to show nontrivial characterizations of graphs of small vertex cover, of bounded tree-depth, of bounded shrub-depth, etc. in terms of forbidden induced finite subgraphs. Furthermore, by the Completeness Theorem, we can compute from
$\varphi $
the corresponding forbidden induced subgraphs. This machinery fails on finite graphs as shown by our results: –There is a class
$\mathscr {C}$
of finite graphs that is definable in first-order logic and closed under induced subgraphs but has no finite set of forbidden induced subgraphs.–Even if we only consider classes
$\mathscr {C}$
of finite graphs that can be characterized by a finite set of forbidden induced subgraphs, such a characterization cannot be computed from a first-order sentence
$\varphi $
that defines
$\mathscr {C}$
and the size of the characterization cannot be bounded by
$f(|\varphi |)$
for any computable function f.Besides their importance in graph theory, the above results also significantly strengthen similar known theorems for arbitrary structures.
The Amazigh Novel, Mythology of Origins, and Return of the Repressed: A Titrological Approach
Authors: Zahir Mohamed 
Published: January 2024

AbstractAmazigh literature has undergone a veritable historic shift from oral to written form, following the constitutional and institutional recognition of this indigenous language in Morocco and Algeria. We intend to seize this historic moment by focusing on a titrological analysis which, in our view, would be able to highlight the pragmatic side of a stammering literature that would like to proclaim its rebirth and speak to the world. The titular discourse of these novels, still in an experimental phase, informs us about the semiospheres that nourish and irrigate this writing that defossilizes a buried memory, repressed and threatened by the inexorable desymbolization process that traditional cultures are undergoing. This body of work could never be reduced to a simple scription of a narrative folklore that provides it with its cultural semantics; it is driven by the desire to integrate the international literary heritage by dialoguing with it and drawing inspiration from it.