bluuebunny/crossref_metadata_2025_split huggingface dataset:
Deposition of clean and contaminated latex particles on pulp fibers
Authors: Alince B. 
Published: September 2005

AbstractElectrostatic interaction between latex particles and oppositely charged surfaces can be affected by the presence of ionic compounds, which are not an integral part of latex particles. They could be formed during polymerization or could be present as emulsifiers. This “free charge” adsorbs on fiber and interferes with latex particles deposition. Consequently, with increasing latex addition, the extent of deposition may decrease. Attempts to explain such unexpected behavior often lead to questionable conclusions. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 98: 1879–1883, 2005
Bone cell viability on methacrylic acid grafted and collagen immobilized porous poly(3‐hydroxybutrate‐co‐3‐hydroxyvalerate)
Authors: Tesema Y. , Raghavan D. , Stubbs J. 
Published: September 2005

AbstractPorous poly(3‐hydroxybutrate‐co‐3‐hydroxyvalerate) (PHBV) film was prepared by solute leaching of salt/PHBV cast film. The surface chemistry of the PHBV membrane was modified by performing graft polymerization of methacrylic acid (MAA) on ozone treated porous PHBV film, followed by immobilization of type I collagen. The surface characteristics of the modified and nonmodified porous films were measured by water contact angle. The rat osteosarcoma cell line UMR‐106 osteoblast like cells were used as model cells to evaluate the cell viability on surfaces. The initial cell attachment, growth pattern, and proliferation as measured by MTT assay were used to evaluate the bone cell viability on the modified and nonmodified films. Among the PHBV films studied, the nonmodified porous PHBV and the porous PHBV film type I collagen dip coated showed no significant difference in cell attachment and proliferation, while the porous PHBV membrane that was collagen immobilized after MAA grafting showed considerable activity of osteoblast like cells. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 98: 1916–1921, 2005
Study on the leveling properties of derivatives of polyethylene glycol for supermilling acid dyes on wool fabrics
Authors: Xie Kongliang , Hou Aiqin , Tian Kun 
Published: September 2005

AbstractThe feasibility of the derivatives of polyethylene glycol as leveling agents in the dyeing process of wool was studied. The interaction between the polymers and dyes affected not only the dyeing rate of supermilling acid dyes on wool but also the absorption spectrum of the dyes. The presence of the polymers improved leveling properties. The dyeing rate was slower in the presence of the polymer than without the polymer. The lower the concentration of dyes, the greater the effect of the polymers in the dyeing process was. The color fastnesses to rubbing, washing, and perspiration of the dyed wool fabrics with the polymer were good. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 98: 1922–1926, 2005
Poly(ethylene terephthalate) nanocomposite fibers by in situ polymerization: The thermomechanical properties and morphology
Authors: Chang Jin‐Hae , Mun Mu Kyung , Lee Ihn Chong 
Published: September 2005

AbstractA series of nanocomposites of poly(ethylene terephthalate) (PET) with the organoclay dodecyltriphenylphosphonium‐mica (C12PPh‐mica) were synthesized with the in situ polymerization method. PET hybrid fibers with various organoclay concentrations were melt‐spun at various draw ratios (DRs) to produce monofilaments. The thermomechanical properties and morphologies of the PET hybrid fibers were characterized with differential scanning calorimetry, thermogravimetric analysis, wide‐angle X‐ray diffraction, electron microscopy, and universal tensile analysis. The organoclay was intercalated in the polymer matrix at all magnification levels, and some of the agglomerated organoclay layers were greater than 50 nm thick. The thermal stabilities and initial tensile moduli of the hybrid fibers increased with an increasing clay content for DR = 1. For DR = 1, the ultimate tensile strengths of the PET hybrid fibers increased with the addition of clay up to a critical clay loading and then decreased above that critical concentration. However, the tensile mechanical properties of the hybrid fibers did not improve with increasing DR. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 98: 2009–2016, 2005
Using theory and research to improve student affairs practice: Some current examples
Authors: Person Dawn R. , Ellis Pilar , Plum Caryn , Boudreau Debra 
Published: September 2005

AbstractThis chapter describes two emerging theories that inform career counseling and explores how they can strengthen student success programs for underrepresented populations. The chapter also describes several effective programs and services that support traditionally underrepresented students as they prepare for, succeed in, and make the transition out of the community college.
Synthesis and Characterization of Core‐Shell Selenium/Carbon Colloids and Hollow Carbon Capsules
Authors: Yu Jimmy C. , Hu Xianluo , Li Quan , Zheng Zhi , Xu Yeming 
Published: September 2005

AbstractA novel Se/C nanocomposite with core‐shell structures has been prepared through a facile one‐pot microwave‐induced hydrothermal process. The new material consists of a trigonal‐Se (t‐Se) core and an amorphous‐C (a‐C) shell. The Se/C composite can be converted to hollow carbon capsules by thermal treatment. These products were characterized by transmission electron microscopy (TEM), powder X‐ray diffraction (XRD), scanning electron microscopy (SEM), selected area electron diffraction (SAED), energy‐dispersive X‐ray (EDX) spectroscopy, and X‐ray photoelectron spectroscopy (XPS).
Tuning pGa with Chelating Agents Related to (o‐Hydroxybenzyl)iminodiacetic Acid
Authors: Jarjayes Olivier , Mortini Florent , du Moulinet d’Hardemare Amaury , Philouze Christian , Serratrice Guy 
Published: September 2005

AbstractGallium complexes with R‐(o‐hydroxybenzyl)iminodiacetate ligands (Lx) have been synthesized and their thermodynamic constants determined in aqueous solution by potentiometric titration. These quantitative results were also confirmed by 1H and 19F NMR spectroscopy. An X‐ray study of GaL3 (R = NO2) showed that the gallium(III) ion is hexacoordinate with two H2O molecules in cis positions. The ability of the ligands to chelate GaIII was evaluated at physiological pH and ionic strength from the pGa values. Among the different ligands studied, L6 (R = OMe) has a pGa value two orders of magnitude higher than that of the complex between Ga and the blood serum protein transferrin. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
Early and Late Transition Metal Complexes Stabilised by Imidazopyridazine‐Substituted Bisamido Ligands
Authors: Irrgang Torsten , Kempe Rhett 
Published: September 2005

AbstractThe preparation of a series of new imidazo[1,5‐b]pyridazine‐substituted diamines (5) is reported. They can be synthesised by the nucleophilic ring transformation of 2‐amino‐5‐methyl‐1,3,4‐oxadiazolium halogenides (1) with diaminoalkanes followed by condensation reactions with 1,3‐diketones. After deprotonation they were then used as bisamido ligands. These ligands stabilise early and late transition metal complexes as five‐membered chelates. The reaction with selected group 4 metals (titanium and zirconium) leads via amine elimination to unusual dark blue and purple mononuclear amido complexes. Deprotonation of the bisamido ligands using BuLi and further reaction with group 6 metals like chromium results in a dinuclear octahedral CrIII complex, where the different coordinated metal centres are bridged by two of the amido N atoms. The double deprotonation of 5 followed by reaction with the group 9 metals rhodium and iridium led to dinuclear complexes in a trans binding mode. The X‐ray structures of one of the novel bisamido ligands (protonated) and all complexes are reported and discussed. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
Fullerene‐Like Nanoballs Formed by Pentaphosphaferrocene and CuBr
Authors: Scheer Manfred , Bai Junfeng , Johnson Brian P. , Merkle Roger , Virovets Alexander V. , Anson Christopher E. 
Published: September 2005

AbstractReaction of [CpxFe(η5‐P5)] {Cpx = η5‐C5Me5 (1a), η5‐C5Me4Et (1b)} with CuBr leads to the fullerene‐like nanoballs [{CpxFe(η5:η1:η1:η1:η1:η1‐P5)}12{CuBr}10{Cu2Br3}5{Cu(CH3CN)2}5] {Cpx = η5‐C5Me5 (5a), η5‐C5Me4Et (5b)} comprising a cluster core of 90 non‐carbon atoms. In contrast to previous results by variation of stoichiometry and concentration conditions, the formation of polymeric product was hindered, and exclusive formation of the spherical cage compound was achieved. The cluster 5b possesses an inside diameter of 1.29 nm and an outside diameter of 2.37 nm. Definitive evidence for encapsulation of a [CpxFe(η5‐P5)] unit (1b) within the inner cavity of the nanocluster 5b is shown by X‐ray crystallographic results. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
Electrochemistry of Benzophenanthridine Alkaloids. Formation and Characterization of Redox Active Films from Products of Sanguinarine and Chelerythrine Oxidation
Authors: Hrbáč Jan , Broncová Gabriela , Matějka Pavel , Bystroň Tomáš , Vrba Jiří , Volf Radko , Vičar Jaroslav 
Published: September 2005

AbstractThe behavior of sanguinarine and chelerythrine alkaloids upon electrochemical oxidation on solid electrodes in buffered aqueous medium is reported in this study. Electro‐oxidation of sanguinarine and chelerythrine results in the formation of redox active electropolymerized films. The films were characterized by cyclic voltammetry, EQCM and surface enhanced Raman scattering spectroscopy excited in near‐infrared range. The electropolymerization is suggested to proceed via formation of alkaloids' ortho‐benzoquinone derivatives.
On accurate boundary conditions for a shape sensitivity equation method
Authors: Duvigneau R. , Pelletier D. 
Published: September 2005

AbstractThis paper studies the application of the continuous sensitivity equation method (CSEM) for the Navier–Stokes equations in the particular case of shape parameters. Boundary conditions for shape parameters involve flow derivatives at the boundary. Thus, accurate flow gradients are critical to the success of the CSEM. A new approach is presented to extract accurate flow derivatives at the boundary. High order Taylor series expansions are used on layered patches in conjunction with a constrained least‐squares procedure to evaluate accurate first and second derivatives of the flow variables at the boundary, required for Dirichlet and Neumann sensitivity boundary conditions. The flow and sensitivity fields are solved using an adaptive finite‐element method. The proposed methodology is first verified on a problem with a closed form solution obtained by the Method of Manufactured Solutions. The ability of the proposed method to provide accurate sensitivity fields for realistic problems is then demonstrated. The flow and sensitivity fields for a NACA 0012 airfoil are used for fast evaluation of the nearby flow over an airfoil of different thickness (NACA 0015). Copyright © 2005 John Wiley & Sons, Ltd.
Identification of new NY‐ESO‐1 epitopes recognized by CD4+ T cells and presented by HLA‐DQ B1 03011
Authors: Karbach Julia , Pauligk Claudia , Bender Armin , Gnjatic Sacha , Franzmann Kerstin , Wahle Claudia , Jäger Dirk , Knuth Alexander , Old Lloyd J. , Jäger Elke 
Published: September 2005

AbstractNY‐ESO‐1 is one of the most immunogenic cancer antigens eliciting strong humoral and cellular immune responses in patients with NY‐ESO‐1‐expressing malignancies. Since CD4+ T cells play a critical role in generating and maintaining antigen‐specific cellular and humoral immune responses, we searched for new NY‐ESO‐1 epitopes presented by MHC class II molecules. CD4+ T cells of patients with NY‐ESO‐1‐expressing cancer were presensitized with 18‐mer overlapping synthetic peptides spanning the entire sequence of NY‐ESO‐1. Two partly overlapping NY‐ESO‐1 epitopes p49‐66 and p55‐72 were identified as targets for NY‐ESO‐1‐specific CD4+ T cells. Peptide‐specific CD4+ T‐cell clones were generated by repetitive stimulation with NY‐ESO‐1 p49‐66 and p55‐72. Further experiments confirmed distinct specificities for the CD4+ T‐cell clones indicating that at least 2 different CD4+ T‐cell epitopes are located in the region p49‐72 of the NY‐ESO‐1 sequence. Using a set of partially histocompatible EBV‐B cell lines and MHC class II‐specific antibodies, we found that both CD4+ T‐cell epitopes were presented in the context of HLA‐DQ B1 03011(DQ7). Natural processing and presentation of these epitopes was demonstrated by recognition of an HLA‐DQ B1 03011‐ and NY‐ESO‐1‐expressing lymphoma cell line and by recognition of dendritic cells (DC) exogenously loaded with NY‐ESO‐1 protein or infected with recombinant NY‐ESO‐1 adenoviral constructs. The specific production of IFN‐γ and TNF‐α suggests that the NY‐ESO‐1‐specific CD4+ T‐cell clones belong to the Th1 subtype. The characterization of the new HLA‐DQ B1 03011‐restricted NY‐ESO‐1 peptides broadens the repertoire of epitopes that can be used to monitor NY‐ESO‐1‐specific spontaneous and vaccine‐induced T‐cell responses in cancer patients. © 2005 Wiley‐Liss, Inc.
Retracted: Transactivation of the ICAM‐1 gene by CD30 in Hodgkin's lymphoma
Authors: Uchihara Jun‐Nosuke , Matsuda Takehiro , Okudaira Taeko , Ishikawa Chie , Masuda Masato , Horie Ryouichi , Watanabe Toshiki , Ohta Takao , Takasu Nobuyuki , Mori Naoki 
Published: September 2005

AbstractRetraction: The following article has been retracted through agreement between the first author and several coauthors, the journal Editor‐in‐Chief, Peter Lichter, and John Wiley & Sons, Ltd.: Uchihara, JN. Matsuda, T. Okudaira, T. Ishikawa, C. Masuda, M. Horie, R. Watanabe, T. Ohta, T. Takasu, N. Mori, N. (2006). Transactivation of the ICAM‐1 gene by CD30 in Hodgkin's lymphoma. Int J Cancer; 118 (March (5)): 1098‐1107, published online on 8 SEP 2005 in Wiley Online Library (www.onlinelibrary.wiley.com). After an investigation the retraction has been agreed due to inappropriate duplication of images and overlap with other published work.
Direct comparison of liquid‐based and conventional cytology in a South African screening trial
Authors: Taylor Sylvia , Kuhn Louise , Dupree William , Denny Lynette , De Souza Michelle , Wright Thomas C. 
Published: September 2005

AbstractOur study directly compares the performance of liquid‐based (LBC) and conventional cytology for detecting high‐grade cervical intraepithelial neoplasia and cancer (CIN 2+) in high‐risk, previously unscreened women. As part of a larger randomized clinical trial assessing the efficacy and safety of a “screen and treat” program for cervical cancer prevention, 5,652 South African women, aged 35 to 65 years, were screened using either ThinPrep or conventional Papanicolaou cytology. The cytology method used (i.e., ThinPrep or conventional) was rotated on a 6‐month basis for the duration of the study. Directly following collection of the cytology specimen, all women underwent colposcopy with endocervical curettage and biopsy of all colposcopic abnormalities. Assessment of cytology and histology results was blinded and results were compared using histology‐confirmed CIN as the “gold standard.” The accuracy of LBC and conventional cytology was statistically equivalent, although the sensitivity of conventional cytology was at least 5 percentage points higher at all cutoff levels. For example, at a cytology cutoff level of low‐grade squamous intraepithelial lesion, the sensitivity of LBC was 60.3% for CIN2+ vs. 69.1% for conventional cytology and specificity was 94.1% and 94.5%, respectively. LBC specimens were significantly less likely to be “satisfactory‐but‐limited‐by” (6.5% vs. 27.9%) but significantly more likely to be unsatisfactory (2.2% vs. 0.8%). Thus, in this high‐risk population, the sensitivity of LBC is no greater than the sensitivity of conventional cytology. Because of the higher unit cost of LBC, low resource settings should carefully consider the potential benefits and drawbacks of LBC before adopting this new technology. © 2005 Wiley‐Liss, Inc.
Intakes of vitamins A, C and E and folate and multivitamins and lung cancer: A pooled analysis of 8 prospective studies
Authors: Cho Eunyoung , Hunter David J. , Spiegelman Donna , Albanes Demetrius , Beeson W. Lawrence , van den Brandt Piet A. , Colditz Graham A. , Feskanich Diane , Folsom Aaron R. , Fraser Gary E. , Freudenheim Jo L. , Giovannucci Edward , Goldbohm R. Alexandra , Graham Saxon , Miller Anthony B. , Rohan Thomas E. , Sellers Thomas A. , Virtamo Jarmo , Willett Walter C. , Smith‐Warner Stephanie A. 
Published: September 2005

AbstractIntakes of vitamins A, C and E and folate have been hypothesized to reduce lung cancer risk. We examined these associations in a pooled analysis of the primary data from 8 prospective studies from North America and Europe. Baseline vitamin intake was assessed using a validated food‐frequency questionnaire, in each study. We calculated study‐specific associations and pooled them using a random‐effects model. During follow‐up of 430,281 persons over a maximum of 6–16 years in the studies, 3,206 incident lung cancer cases were documented. Vitamin intakes were inversely associated with lung cancer risk in age‐adjusted analyses; the associations were greatly attenuated after adjusting for smoking and other risk factors for lung cancer. The pooled multivariate relative risks, comparing the highestvs.lowest quintile of intake from food‐only, were 0.96 (95% confidence interval (CI) 0.83–1.11) for vitamin A, 0.80 (95% CI 0.71–0.91) for vitamin C, 0.86 (95% CI 0.76–0.99) for vitamin E and 0.88 (95% CI 0.74–1.04) for folate. The association with vitamin C was not independent of our previously reported inverse association with β‐cryptoxanthin. Further, vitamin intakes from foods plus supplements were not associated with a reduced risk of lung cancer in multivariate analyses, and use of multivitamins and specific vitamin supplements was not significantly associated with lung cancer risk. The results generally did not differ across studies or by sex, smoking habits and lung cancer cell type. In conclusion, these data do not support the hypothesis that intakes of vitamins A, C and E and folate reduce lung cancer risk. © 2005 Wiley‐Liss, Inc.
Epidermal growth factor receptor mutations in needle biopsy/aspiration samples predict response to gefitinib therapy and survival of patients with advanced nonsmall cell lung cancer
Authors: Shih Jin‐Yuan , Gow Chien‐Hung , Yu Chong‐Jen , Yang Chih‐Hsin , Chang Yih‐Leong , Tsai Meng‐Feng , Hsu Ya‐Chieh , Chen Kuan‐Yu , Su Wen‐Pin , Yang Pan‐Chyr 
Published: September 2005

AbstractRecently, mutations in the epidermal growth factor receptor (EGFR) gene in nonsmall cell lung cancer (NSCLC) patients were reported to correlate with gefitinib response. Less than 30% of NSCLC patients are surgically resectable; however, molecular analysis has to rely on nonsurgical diagnostic tissue samples. The objective of this study is to investigate EGFR mutation analysis on needle biopsy/aspiration samples and its correlations with gefitinib response and patients' survival. EGFR mutation was assessed from DNA of 63 paraffin‐embedded small needle biopsy/aspiration specimens from 62 patients with NSCLC treated with gefitinib. The peripheral blood lymphocyte DNA of the patients was sequenced to verify the EGFR mutation. EGFR mutations were found in 47% of 62 patients (60% of 20 CT‐guided biopsies, 44% of 18 ultrasound‐guided biopsies, 31% of 16 endoscopic biopsies and 44% of 9 effusion cell blocks). EGFR mutations were frequently present in females (p = 0.006) and never smokers (p = 0.04). Patients with EGFR mutations had a significantly better response rate compared to that of the nonmutation group (p < 0.001). Multivariate analysis showed that EGFR mutation (p < 0.001) and PS 0–1 (p = 0.02) were independently associated with a better response rate. Cox regression analysis showed that EGFR mutation was the independent prognostic factor for progression‐free survival (p = 0.008) and overall survival (p = 0.03). In conclusion, EGFR mutation analysis is feasible in needle biopsy/aspiration paraffin‐fixed specimens. EGFR mutation is an independent predictor of gefitinib response and survival in patients of advanced NSCLC treated by gefitinib. © 2005 Wiley‐Liss, Inc.
Enhancing the antitumor activity of ErbB blockade with histone deacetylase (HDAC) inhibition
Authors: Chinnaiyan Prakash , Varambally Sooryanarayana , Tomlins Scott A. , Ray Soma , Huang Shyhmin , Chinnaiyan Arul M. , Harari Paul M. 
Published: September 2005

AbstractMolecular inhibition of the ErbB signaling pathway represents a promising cancer treatment strategy. Preclinical studies suggest that enhancement of antitumor activity can be achieved by maximizing ErbB signaling inhibition. Using cDNA microarrays, we identified histone deacetylase (HDAC) inhibitors as having strong potential to enhance the effects of anti‐ErbB agents. Studies using a 20,000 element (20K) cDNA microarray demonstrate decreased transcript expression of ErbB1 (epidermal growth factor receptor) and ErbB2 in DU145 (prostate) and ErbB2 in SKBr3 (breast) cancer cell lines. Additional changes in the DU145 gene expression profile with potential interaction to ErbB signaling include down‐regulation of caveolin‐1 and hypoxia inducible factor 1‐α (HIF1‐α), and up‐regulation of gelsolin, p19(INK4D) and Nur77. Findings were validated using real time RT‐PCR and Western blot analysis. Enhanced proliferative inhibition, apoptosis induction and signaling inhibition were demonstrated when combining HDAC inhibition with ErbB blockade. These results suggest that used cooperatively, anti‐ErbB agents and HDAC inhibitors may offer a promising strategy of dual targeted therapy. Additionally, microarray data suggest that the beneficial interaction of these agents may not derive solely from modulation of ErbB expression, but may result from effects on other oncogenic processes including angiogenesis, invasion and cell cycle kinetics. © 2005 Wiley‐Liss, Inc.
Identification of α‐fetoprotein‐derived peptides recognized by cytotoxic T lymphocytes in HLA‐A24+ patients with hepatocellular carcinoma
Authors: Mizukoshi Eishiro , Nakamoto Yasunari , Tsuji Hirokazu , Yamashita Tatsuya , Kaneko Shuichi 
Published: September 2005

Abstractα‐Fetoprotein (AFP) has been proposed as a potential target forT‐cell‐based immunotherapy for hepatocellular carcinoma (HCC), but the number of its epitopes that have been identified is limited and the status of AFP‐specific immunological responses in HCC patients has not been well‐characterized. To address the issue, we examined the possibility of inducing AFP‐specific cytotoxic T cells (CTLs) using novel HLA‐A*2402‐restricted T‐cell epitopes (HLA, human leukocyte antigen) derived from AFP and then analyzed the relationship between its frequency of occurrence and clinical features associated with patients having HCC. Five AFP‐derived peptides containing HLA‐A*2402 binding motifs and showing high binding affinity to HLA‐A*2402 induced CTLs to produce IFN‐γ and kill an AFP‐producing hepatoma cell line. The frequency of AFP‐specific CTLs was 30–190 per 1 × 106 peripheral blood mononuclear cells, which was the same as that of other immunogenic cancer associated antigen‐derived epitopes. Analyses of the relationships between AFP‐specific CTL responses and clinical features of patients with HCC revealed that AFP epitopes were more frequently recognized by CTLs in patients with advanced HCC correlating to tumor factors or the stage of TNM classification. The analyses of CTL responses before and after HCC treatments showed that the treatments changed the frequency of AFP‐specific CTLs. In conclusion, we identified five HLA‐A*2402‐restrictedT‐cell epitopes derived from AFP. The newly identified AFP epitopes could be a valuable component of HCC immunotherapy and for analyzing host immune responses to HCC. © 2005 Wiley‐Liss, Inc.