bluuebunny/crossref_metadata_2025_split huggingface dataset:
Radio continuum from the most massive early-type galaxies detected with ASKAP RACS
Authors: Brown Michael J.I. , Clarke Teagan A. , Hopkins Andrew M. , Norris Ray P. , Jarrett T.H. 
Published: December 2023

Abstract
All very massive early-type galaxies contain supermassive blackholes, but are these blackholes all sufficiently active to produce detectable radio continuum sources? We have used the 887.5 MHz Rapid ASKAP Continuum Survey DR1 to measure the radio emission from morphological early-type galaxies brighter than

$K_S=9.5$

selected from the 2MASS Redshift Survey, HyperLEDA, and RC3. In line with previous studies, we find median radio power increases with infrared luminosity, with

$P_{1.4} \propto L_K^{2.2}$

, although the scatter about this relation spans several orders of magnitude. All 40 of the

$M_K<-25.7$

early-type galaxies in our sample have measured radio flux densities that are more than

$2\sigma$

above the background noise, with

$1.4\,{\rm GHz}$

radio powers spanning

${\sim} 3 \times 10^{20}$

to

${\sim} 3\times 10^{25}\,{\rm W/Hz^{-1}}$

. Cross-matching our sample with integral field spectroscopy of early-type galaxies reveals that the most powerful radio sources preferentially reside in galaxies with relatively low angular momentum (i.e. slow rotators). While the infrared colours of most galaxies in our early-type sample are consistent with passive galaxies with negligible star formation and the radio emission produced by active galactic nuclei or AGN remnants, very low levels of star formation could power the weakest radio sources with little effect on many other star formation rate tracers.
Citizenship and mobility of the poor: Sweden during the 19th century
Authors: Kalm Sara 
Published: December 2023

AbstractThe distinctive features of the modern form of citizenship include, among other things, that it is both internally inclusive and externally exclusive; that it establishes legal equality so that membership of the state supersedes all other memberships and allegiances; and that it defines membership as independent of residence. These characteristics largely evolved during the “long nineteenth century”, the period between the French Revolution and the First World War. Similar to that of today, the historical situation in which citizenship evolved was one of intensified mobility. With the example of Sweden, this article finds that citizenship, in both its internal and external dimensions, was elaborated partly as a way to manage the mobility of the migrant poor. The contours of citizenship emerged as authorities aimed to control and direct the movement of the poor, which preceded control efforts. This has implications for our understanding of citizenship as well as of the state, and highlights the agency of migrants.
Community Size and Electoral Preferences: Evidence From Post-Second World War Baden-Württemberg
Authors: Fiorini Luciana , Jetter Michael , Parmeter Christopher F. , Parsons Christopher 
Published: December 2023

AbstractWe examine whether electoral preferences depend on a community's population size by studying post-Second World War Baden-Württemberg in Southwest Germany. Our identification strategy exploits the fact that the French administration zone prohibited German expellees from entering, contrary to the contiguous American zone. Population size positively predicts voting for the Social Democrats (the party advocating substantial government involvement in practically all domains) and negatively for the Christian Democrats (the small-government party advocating free-market policies). Results are neither driven by pre-existing voting patterns, religious compositions, and location- and time-specific unobservables, nor other measurable cultural, demographic, economic, or political characteristics. Alternative explanations pertaining to expellee voting behaviour or a backlash of natives against expellees appear unlikely – population size prevails as a predominant voting predictor.
Unitary groups,
$\boldsymbol{K}$
-theory, and traces
Authors: Sarkowicz Pawel 
Published: December 2023

AbstractWe show that continuous group homomorphisms between unitary groups of unital C*-algebras induce maps between spaces of continuous real-valued affine functions on the trace simplices. Under certain
$K$
-theoretic regularity conditions, these maps can be seen to commute with the pairing between
$K_0$
and traces. If the homomorphism is contractive and sends the unit circle to the unit circle, the map between spaces of continuous real-valued affine functions can further be shown to be unital and positive (up to a minus sign).
Impact of resveratrol and zinc on biomarkers of oxidative stress induced by Trichinella spiralis infection
Authors: Salama M.A. , Alabiad M.A. , Saleh A.A. 
Published: December 2023

Abstract
Trichinellosis is a re-emerging worldwide foodborne zoonosis. Oxidative stress is one of the most common detrimental effects caused by trichinellosis. In addition, Trichinella infection poses an infinite and major challenge to the host’s immune system. Resistance and side effects limit the efficiency of the existing anti-trichinella medication. Given that concern, this work aimed to investigate the anti-helminthic, antioxidant, anti-inflammatory and immunomodulatory effects of resveratrol and zinc during both phases of Trichinella spiralis infection. Sixty-four Swiss albino mice were divided into four equal groups: non-infected control, infected control, infected and treated with resveratrol, and infected and treated with zinc. Animals were sacrificed on the 7th and 35th days post-infection for intestinal and muscular phase assessments. Drug efficacy was assessed by biochemical, parasitological, histopathological, immunological, and immunohistochemical assays. Resveratrol and zinc can be promising antiparasitic, antioxidant, anti-inflammatory, and immunomodulatory agents, as evidenced by the significant decrease in parasite burden, the significant improvement of liver and kidney function parameters, the increase in total antioxidant capacity (TAC), the reduction of malondialdehyde (MDA) level, the increase in nuclear factor (erythroid-derived 2)-like-2 factor expression, and the improvement in histopathological findings. Moreover, both drugs enhanced the immune system and restored the disturbed immune balance by increasing the interleukin 12 (IL-12) level. In conclusion, resveratrol and zinc provide protection for the host against oxidative harm and the detrimental effects produced by the host’s defense response during Trichinella spiralis infection, making them promising natural alternatives for the treatment of trichinellosis.
Fractional order inspired iterative adaptive control
Authors: Varga Bence , Tar József K. , Horváth Richárd 
Published: December 2023

AbstractAlthough several studies have revealed that fractional order controllers usually outperform conventional integer-order control solutions, fractional order controllers are not yet widely applied in industrial applications due to their complex mathematical background. In this paper, further improvements of a simple weighted sum feedback design are introduced that imitates the behavior of a fractional order controller but is free from its various formal restrictions. The proposed control solution has the main characteristics of a fractional order controller, such as finite memory length, excellent transient response with no overshoot and robust behavior, but it is placed into a much simpler mathematical framework. In the current paper, a simple derivative term was incorporated in the design which made the controller’s output more stable by completely eliminating output chattering. The proposed control method was developed for a general second-order system. It was tested in a fixed point iteration-based adaptive control scenario, through simulations using a robotic example and on experimental basis as well, utilizing a simple one-degree-of-freedom electromechanical system. The presented experiments are the first systematic investigations of the fixed point iteration-based adaptive control method.
Shock models governed by an inverse gamma mixed Poisson process
Authors: Iuliano Antonella , Martinucci Barbara , Mustaro Verdiana 
Published: December 2023

AbstractWe study three classes of shock models governed by an inverse gamma mixed Poisson process (IGMP), namely a mixed Poisson process with an inverse gamma mixing distribution. In particular, we analyze (1) the extreme shock model, (2) the δ-shock model, and the (3) cumulative shock model. For the latter, we assume a constant and an exponentially distributed random threshold and consider different choices for the distribution of the amount of damage caused by a single shock. For all the treated cases, we obtain the survival function, together with the expected value and the variance of the failure time. Some properties of the inverse gamma mixed Poisson process are also disclosed.
Evaluation of indigenous and exotic soybean accessions for yield, resistance to frog-eye leaf spot and yellow mosaic virus diseases
Authors: Bhartiya Anuradha , Rajesh Vangala , Aditya J. P. , B. Jeevan , Gupta Sanjay , Kant Lakshmi , Joshi Hemlata , Mehtre S. P. , Devi H. N. , Jaybhay S. , Karnwal M. K. , Nataraj Vennampally , Khandekar Nita 
Published: December 2023

AbstractSoybean is a major source of vegetable oil and protein worldwide. Globally, India is among the top five producers where soybean is a major oilseed grown under diverse agro-climatic conditions by small and marginal farmers. The present study aims to identify soybean varieties with higher yield levels, resistance to pestdiseases and adaptability to climatic fluctuations. One hundred and twenty-five (125) indigenous and exotic soybean germplasm accessions and five checks were evaluated and characterized for eight agro-morphological traits at five testing locations and also screened for frog-eye leaf spot (FLS) and yellow mosaic virus (YMV) diseases under hot-spot locations during the rainy season. A wide range of variability was observed among accessions for days to 50% flowering (39–59), plant height (41–111 cm), number of nodes/plant (10–30), pod clusters/plant (14–39), number of pods/plant (40–102), days to maturity (96–115), grain yield/plant (4.89–16.54 g) and 100-seed weight (6.02–13.72 g). Among various traits, 100-seed weight (0.45), number of pods/plant (0.60) and number of pod clusters/plant (0.38) were found to be major yield-contributing traits as they exhibited highly significant correlation with grain yield/plant. Principal components PCI and PCII with eigen value >1 accounted for 42.66 and 27.08% of the total variation, respectively. Accessions G24 (EC 393222) from Taiwan and G40 (IMP-1) from the USA belonging to cluster IV were found promising for multiple yield traits and JS 20–38 from cluster III for earliness as per cluster analysis. GGE biplot average environment coordination (AEC) view revealed that the accessions viz., G11 (EC 333872), G2 (EC 251506) and G47 (TNAU-S-55) were the best performing stable genotypes in terms of grain yield/plant across locations. Twelve accessions had a high level of resistance against both FLS and YMV diseases under natural hot-spot conditions which can be utilized as promising donors in the soybean breeding programme.
Contrasting Seasonal Isotopic Signatures of Near‐Surface Atmospheric Water Vapor in the Central Arctic During the MOSAiC Campaign
Authors: Brunello C. F. , Meyer H. , Mellat M. , Casado M. , Bucci S. , Dütsch M. , Werner M. 
Published: December 2023

AbstractThe Arctic is experiencing unprecedented moistening which is expected to have far‐reaching impact on global climate and weather patterns. However, it remains unclear whether this newly sourced moisture originates locally from ice‐free ocean regions or is advected from lower latitudes. In this study, we use water vapor isotope measurements in combination with trajectory‐based diagnostics and an isotope‐enabled atmosphere general circulation model, to assess seasonal shifts in moisture sources and transport pathways in the Arctic. Continuous measurements of near‐surface vapor, δ18O, and δD were performed onboard RV Polarstern during the Multidisciplinary drifting Observatory for the Study of Arctic Climate expedition from October 2019 to September 2020. Combining this isotope data set with meteorological observations reveals that the spatiotemporal evolution of δ18O mimics changes in local temperature and humidity at synoptic to seasonal time scales, while corresponding d‐excess changes suggest a seasonal shift in the origin of moisture. Simulation results from the particle dispersion model FLEXPART support these findings, indicating that summer moisture originates from nearby open ocean, while winter moisture comes from more remote sources with longer residence time over sea‐ice. Results from a nudged ECHAM6‐wiso simulation also indicate that evaporative processes from the ocean surface reproduce summer isotope values, but are insufficient to explain measured winter isotope values. Our study provides the first isotopic characterization of Central Arctic moisture over the course of an entire year, helping to differentiate the influence of local processes versus large‐scale vapor transport on Arctic moistening. Future process‐based investigations should focus on assessing the non‐equilibrium isotopic fractionation during airmass transformation over sea‐ice.
nmrrr: A Reproducible Workflow for Binning and Visualizing NMR Spectra From Environmental Samples
Authors: Patel Kaizad F. , Myers‐Pigg Allison N. , Bond‐Lamberty Ben , Barnes Morgan E. 
Published: December 2023

AbstractNuclear magnetic resonance (NMR) spectroscopy is a useful tool for detection and identification of molecular structural information, with increasing applications in environmental sciences. NMR instrument outputs are however heterogeneous and require extensive post‐processing, creating barriers to their use and application by non‐specialists. Here, we report on a new open‐source R package,nmrrr, that processes and visualizes spectral data obtained from one‐dimensional solution‐state and solid‐state NMR experiments; the package also performs relevant calculations commonly applied in natural organic matter communities, such as computing the relative abundance of various functional groups. We document the package's installation, dependencies, and functions; and provide a standard workflow for processing NMR data. This package is currently available on CRAN and GitHub, and community contributions are welcome.
The East Bay Diesel Exposure Project: a biomonitoring study of parents and their children in heavily impacted communities
Authors: Sultana Daniel , Kauffman Duyen , Castorina Rosemary , Paulsen Michael H. , Bartlett Russell , Ranjbar Kelsey , Gunier Robert B. , Aguirre Victor , Rowen Marina , Garban Natalia , DeGuzman Josephine , She Jianwen , Patterson Regan , Simpson Christopher D. , Bradman Asa , Hoover Sara 
Published: December 2023

Abstract
Background
Diesel exhaust (DE) exposures pose concerns for serious health effects, including asthma and lung cancer, in California communities burdened by multiple stressors.

Objective
To evaluate DE exposures in disproportionately impacted communities using biomonitoring and compare results for adults and children within and between families.

Methods
We recruited 40 families in the San Francisco East Bay area. Two metabolites of 1-nitropyrene (1-NP), a marker for DE exposures, were measured in urine samples from parent–child pairs. For 25 families, we collected single-day spot urine samples during two sampling rounds separated by an average of four months. For the 15 other families, we collected daily spot urine samples over four consecutive days during the two sampling rounds. We also measured 1-NP in household dust and indoor air. Associations between urinary metabolite levels and participant demographics, season, and 1-NP levels in dust and air were evaluated.

Results
At least one 1-NP metabolite was present in 96.6% of the urine samples. Detection frequencies for 1-NP in dust and indoor air were 97% and 74%, respectively. Results from random effect models indicated that levels of the 1-NP metabolite 6-hydroxy-1-nitropyrene (6-OHNP) were significantly higher in parents compared with their children (p-value = 0.005). Urinary 1-NP metabolite levels were generally higher during the fall and winter months. Within-subject variability was higher than between-subject variability (~60% of total variance versus ~40%, respectively), indicating high short-term temporal variability.

Impact
Biomonitoring, coupled with air monitoring, improves understanding of hyperlocal air pollution impacts. Results from these studies will inform the design of effective exposure mitigation strategies in disproportionately affected communities.
DELE1 haploinsufficiency causes resistance to mitochondrial stress-induced apoptosis in monosomy 5/del(5q) AML
Authors: Spinella Jean-François , Chagraoui Jalila , Moison Céline , Lavallée Vincent P. , Boivin Isabel , Gracias Deanne , Lavallée Sylvie , Carpentier Guillaume Richard , Beliveau François , Hébert Josée , Sauvageau Guy 
Published: December 2023

AbstractMonosomy 5 and deletions of the chromosome 5q (−5/del(5q)) are recurrent events in de novo adult acute myeloid leukemia (AML), reaching up to 40% of cases in secondary AML. These chromosome anomalies are associated with TP53 mutations and with very poor prognosis. Using the large Leucegene genomic and transcriptomic dataset composed of 48 −5/del(5q) patient specimens and 367 control AML, we identified DELE1 – located in the common deleted region – as the most consistently downregulated gene in these leukemias. DELE1 encodes a mitochondrial protein recently characterized as the relay of mitochondrial stress to the cytosol through a newly defined OMA1-DELE1-HRI pathway which ultimately leads to the activation of ATF4, the master transcription factor of the integrated stress response. Here, we showed that the partial loss of DELE1 expression observed in −5/del(5q) patients was sufficient to significantly reduce the sensitivity to mitochondrial stress in AML cells. Overall, our results suggest that DELE1 haploinsufficiency could represent a new driver mechanism in −5/del(5q) AML.
Urine-derived bladder cancer organoids (urinoids) as a tool for cancer longitudinal response monitoring and therapy adaptation
Authors: Viergever Bastiaan J. , Raats Daniëlle A. E. , Geurts Veerle , Mullenders Jasper , Jonges Trudy N. , van der Heijden Michiel S. , van Es Johan H. , Kranenburg Onno , Meijer Richard P. 
Published: December 2023

Abstract
Background
Bladder cancer is one of the most common cancer types worldwide. Generally, research relies on invasive sampling strategies.

Methods
Here, we generate bladder cancer organoids directly from urine (urinoids). In this project, we establish 12 urinoid lines from 22 patients with non-muscle and muscle-invasive bladder tumours, with an efficiency of 55%.

Results
The histopathological features of the urinoids accurately resemble those of the original bladder tumours. Genetically, there is a high concordance of single nucleotide polymorphisms (92.56%) and insertions & deletions (91.54%) between urinoids and original tumours from patient 4. Furthermore, these urinoids show sensitivity to bladder cancer drugs, similar to their tissue-derived organoid counterparts. Genetic analysis of longitudinally generated tumoroids and urinoids from one patient receiving systemic immunotherapy, identify alterations that may guide the choice for second-line therapy. Successful treatment adaptation was subsequently demonstrated in the urinoid setting.

Conclusion
Therefore, urinoids can advance precision medicine in bladder cancer as a non-invasive platform for tumour pathogenesis, longitudinal drug-response monitoring, and therapy adaptation.
An alternative fully human anti-BCMA CAR-T shows response for relapsed or refractory multiple myeloma with anti-BCMA CAR-T exposures previously
Authors: Wang Qingming , Wei Runhong , Guo Shufang , Min Chao , Zhong Xiong , Huang Hui , Cheng Zhi 
Published: December 2023

AbstractChimeric antigen receptor T (CAR-T) cells therapy has made remarkable progress in relapsed/refractory multiple myeloma (R/R MM) treatment. Unfortunately, patients still eventually experience disease progression or relapse even after receiving anti-BCMA CAR-T therapy. At present, there are limited data on available treatment options for patients who have progressed on anti-BCMA CAR-T therapy. In this study, we evaluated the safety and efficacy of fully human anti-BCMA CAR-T (HRC0202) in seven R/R MM patients who were previously exposed to anti-BCMA CAR-T therapy. Three patients received 6.0 × 106 CAR+T cells/kg, one patient received 10.0 × 106 CAR+T cells/kg and three patients received 15.0 × 106 CAR+T cells/kg. Cytokine release syndrome (CRS) of grades 1–2 occurred in three patients (42.9%) and grade ≥3 in two patients (28.6%). Immune effector cell-associated neurotoxic syndrome (ICANS) was not observed in any of the patients. The best overall response rate (ORR) was 71.4% (5/7), with a stringent complete response/complete response (sCR/CR) achieved in three patients. The median progression-free survival (PFS) was 269 days, and median overall survival (OS) for all patients was not reached. The median peak concentration (Cmax) of HRC0202 was 30117.70 (range, 6084.35–147415.10) copies/μg DNA. This study indicated that fully human anti-BCMA CAR-T (HRC0202) is a promising treatment for R/R MM patients who relapsed or refractory from prior anti-BCMA CAR-T infusion.
Emerging applications of tough ionogels
Authors: Wang Meixiang , Hu Jian , Dickey Michael D. 
Published: December 2023

AbstractIonogels are crosslinked networks—typically polymeric networks—swollen with ionic liquids. The unique properties of ionogels, such as nonvolatility, ionic conductivity, nonflammability, and high thermal and electrochemical stability, make them promising for a variety of applications. Examples include sensors, adhesives, energy storage devices, and ionotronics. While many ionogels require complex syntheses and suffer from poor mechanical properties, simpler strategies are emerging to produce tough ionogels, thereby improving the durability, enabling 3D printing, and broadening the application space of ionogels. This perspective highlights promising applications and future opportunities of ionogels.