bluuebunny/crossref_metadata_2025_split huggingface dataset:
Preoperative Imaging and Surgical Findings in Pediatric Frontonasal Dermoids
Authors: Amin Shaunak N. , Siu Jennifer M. , Purcell Patricia L. , Manning James P. , Wright Jason , Dahl John P. , Hauptman Jason S. , Hopper Richard A. , Lee Amy , Manning Scott C. , Perkins J. Nathaniel , Susarla Srinivas M. , Bly Randall A. 
Published: September 2023

ObjectiveTo review cases of congenital frontonasal dermoids to gain insight into the accuracy of preoperative computed tomography (CT) and magnetic resonance imaging (MRI) in predicting intracranial extension.MethodsThis retrospective study included all patients who underwent primary excision of frontonasal dermoids at an academic children's hospital over a 23‐year period. Preoperative presentation, imaging, and operative findings were reviewed. Receiver operating characteristic (ROC) statistics were generated to determine CT and MRI accuracy in detecting intracranial extension.ResultsSearch queries yielded 129 patients who underwent surgical removal of frontonasal dermoids over the study period with an average age of presentation of 12 months. Preoperative imaging was performed on 122 patients, with 19 patients receiving both CT and MRI. CT and MRI were concordant in the prediction of intracranial extension in 18 out of 19 patients. Intraoperatively, intracranial extension requiring craniotomy was seen in 11 patients (8.5%). CT was 87.5% sensitive and 97.4% specific for predicting intracranial extension with an ROC of 0.925 (95% CI [0.801, 1]), whereas MRI was 60.0% sensitive and 97.8% specific with an ROC of 0.789 (95% CI [0.627, 0.950]).ConclusionThis is the largest case series in the literature describing a single institution's experience with frontonasal dermoids. Intracranial extension is rare and few patients required craniotomy in our series. CT and MRI have comparable accuracy at detecting intracranial extension. Single‐modality imaging is recommended preoperatively in the absence of other clinical indications.Level of Evidence4 Laryngoscope, 134:1961–1966, 2024
Usefulness of Intraoperative Narrow‐Band Imaging in the Site Diagnosis of Respiratory Papillomatosis
Authors: Matsuda Keishi , Matsuzaki Hiroumi , Fujiwara Dai , Makiyama Kiyoshi , Oshima Takeshi 
Published: September 2023

ObjectiveNarrow‐band imaging (NBI) is considered useful for detecting respiratory papillomatosis. However, the choice between preoperative and intraoperative NBI depends on the facility. We investigated the usefulness of NBI and determined whether preoperative NBI can replace intraoperative NBI with a comparable detection rate.MethodsIn this retrospective cohort study conducted at single a tertiary care center, patients with respiratory papillomatosis treated between 2017 and 2022 were enrolled. We systematically compared preoperative white light imaging (WLI) with preoperative and intraoperative NBI. The primary endpoints were the papilloma detection rate and lesion site assessed by the Derkay scoring system. The secondary endpoints were the risk factors for increased Derkay scores.ResultsThe study included 127 patients with papilloma. Intraoperative NBI yielded significantly higher Derkay scores than preoperative WLI (p < 0.001) and preoperative NBI (p = 0.004). The papilloma detection rates of preoperative WLI and preoperative NBI were not significantly different. Intraoperative NBI detected more lesions than preoperative NBI in 37 of 127 (29%) patients; the overall number of additional lesions was 47 of 279 (17%). Compared with preoperative NBI, intraoperative NBI yielded significantly higher scores for the vocal cords (p = 0.005), false vocal cords (p = 0.010), and ventricle of the larynx (p < 0.001). Elevated Derkay scores were significantly associated with male sex (p = 0.012) and alcohol consumption (p = 0.007).ConclusionIntraoperative NBI is more accurate in detecting papillomatous lesions, and preoperative NBI cannot replace intraoperative NBI.Level of Evidence4 Laryngoscope, 134:1820–1824, 2024
Now you have to pay! A deeper look at publishing practices of predatory journals
Authors: Freiermuth Mark R. 
Published: September 2023

AbstractIn this study, by using Beall's (Scholarly open‐access, 2014; Beall's list of predatory journals and publishers, 2018) predatory journal lists as well as direct e‐mail solicitations from journals, we intentionally submitted a poorly written manuscript to 58 open‐access journals using counterfeit names and affiliations. Although there have been several studies examining the practices of questionable journals, there is a lack of research investigating the interactive processes in detail. Our analysis, then, was to provide a more comprehensive view of the underlying reasoning for the acceptance or rejection of a manuscript. Of the 31 journals acknowledging receipt of our manuscript, 21 accepted it either unexpurgated or asked only for cosmetic revisions. Regarding ‘positive responses’, we point to five common flaws associated with such journals, namely that (1) they lack any interest in the researchers who are submitting manuscripts; (2) they do not judge academic writing in accordance with expected conventions; (3) they appear to be indifferent to scholarship including research design, plagiarism issues, and citation quality; (4) their review process is opaque and overly hasty, and (5) the tone they use in correspondence e‐mail messages is highly inappropriate. Based upon the investigation, it is clear that such journals' primary aim is in securing the article processing fee. Our findings paint a more comprehensive picture of questionable journal practices with the hope of disseminating such information to the broader scholarly community.
Measuring the Interactions and Influence of Amphipathic Copolymers with Lipid Monolayers and Bilayers as Models of Biological Membranes
Authors: Frost Charlotte , Wiedbrauk Sandra , Graham Elizabeth , Yepuri Nageshwar R. , Nelson Andrew R. J. , Boase Nathan R. B. 
Published: September 2023

AbstractAmphipathic copolymers are useful materials for nanomedicine, owing to their ability to self‐assemble into nanoparticles, act as surfactants for inorganic materials, or for their favorable interactions with lipid membranes. Despite their widespread use, there is still a range of questions about the physicochemical properties that are necessary to drive their interactions at biological interfaces. To fully understand these interactions requires a diverse range of complementary analytical techniques. In this work, a library of neutral amphipathic methacrylate copolymers is synthesized by reversible addition‐fragmentation chain‐transfer polymerization (RAFT) polymerization, to investigate the effect of polymer composition and nature of the hydrophobic comonomer on interactions with model lipid membranes. These materials are shown to interact with Langmuir lipid monolayers, and neutron reflectometry demonstrates that hydrophobic interactions lead to the polymers intercalating with the monolayers. More complex models of lipid bilayers are studied using an in situ quartz crystal microbalance (QCM) model and shows while the composition and hydrophobic comonomer affect the stability of these interactions, there is no effect on the viscoelasticity of the lipid membranes. The in‐depth understanding of these interfacial interactions afforded by this suite of analytical tools will allow for more complex copolymers to be studied, providing a greater understanding of key processes in nanomedicine, such as cellular entry and endosomal escape.
Federal, state funding announcements boost youth MH services
Authors: Enos Gary 
Published: September 2023

The Biden administration last week announced an award of $206 million in grants designed to expand access to community‐ and school‐based mental health services for youths. Coinciding with the Sept. 25 funding announcement, the state of Virginia received confirmation that the Centers for Medicare & Medicaid Services (CMS) has approved its proposed expansion of Medicaid funding availability for school‐based health services in the state.
Ultraviolet light differentially reduces viability of fish- and fish farm-associated flavobacteria (families Flavobacteriaceae and Weeksellaceae)
Authors: Knupp Christopher , Faisal Mohamed , Brenden Travis O. , Soto Esteban , LaFrentz Benjamin R. , Griffin Matt J. , Wiens Gregory D. , Cavender Wade , Van Vliet Danielle , Loch Thomas P. 
Published: September 2023

Abstract

Objective
Globally, flavobacteria (family Flavobacteriaceae and Weeksellaceae) are leading causes of disease-related losses in fish-farms and hatcheries. One route flavobacteria gain access to aquaculture facilities is via source water. Ultraviolet (UV) light treatment of source water has been effective in reducing the risk of disease outbreaks caused by nonflavobacteria; however, the UV dose required to inactivate flavobacteria has been understudied. The primary objective of this study was to examine the efficacy of UV light treatments for reducing the viability of fish-pathogenic and fish-associated Flavobacterium and Chryseobacterium species in a planktonic form.

Methods
Sixty-five flavobacterial isolates belonging to ten Flavobacterium spp. and Chryseobacterium spp. were exposed to a low (25 mJ/cm2) and high (126 mJ/cm2) dose of UV light via a collimating beam apparatus under in vitro conditions, after which treatment efficacy was determined via culture.

Result
All assayed flavobacteria were reduced by an average of ~1000-fold or ~100,000-fold at the low and high UV doses, respectively; however, substantial differences in reduction at the same UV dose were noted among isolates of the same flavobacterial species, including F. psychrophilum, F. columnare, and F. oreochromis. In addition, F. psychrophilum multilocus sequence typing variants ST10 and ST78, which are two of the most widespread variants in the United States of America, were among the least susceptible to ultraviolet light.

Conclusion
Overall, results demonstrate that viable flavobacteria can be reduced substantially by ultraviolet doses of 25–126 mJ/cm2, suggesting such treatments represent a promising tool for minimizing flavobacterial loads in hatcheries and aquaculture facilities, thereby enhancing biosecurity and reducing the risk of epizootics.
Effects of live-imaging sonar on Blue Catfish angler success, perception, and behavior
Authors: Neely Ben C. , Koch Jeff D. , Gido Keith B. 
Published: September 2023

Abstract

Objective
Proliferation of consumer-grade live-imaging sonar (LIS) has created management challenges in recreational fisheries. Most pervasive is the question about whether LIS users catch fish more effectively than nonusers. This project was designed to elucidate the effects of LIS use on catch of Blue Catfish Ictalurus furcatus from the Milford Reservoir, Kansas. Additionally, we sought to identify angler perception of LIS and quantify differences in angling behavior between users and nonusers.

Methods
We organized a Blue Catfish angling experiment where 16 anglers used LIS and 16 anglers did not. The experiment was followed by dissemination of a survey to measure angler experience and skill, measure perception of LIS, and identify behavior patterns from groups that did and did not have access to the technology. A multivariate linear model was used to identify how LIS use, angling experience, and self-assessed angling skill influenced fish catch. Comparisons of LIS perceptions and angling behavior were also evaluated between treatment groups.

Result
There was no difference in Blue Catfish mass captured per 5-h angling trial by anglers using LIS (mean = 14.57 kg, SE = 3.38) and anglers not using LIS (mean = 16.97 kg, SE = 2.29). However, self-rating of angling skill was identified as a predictor in a supported model but little variation in catch was explained (R2 = 0.169). Anglers using LIS thought their time spent searching and catch would have been similar if they did not use LIS. Anglers that did not use LIS thought they would spend more time searching for fish and catch may have increased if using LIS. Time spent searching for angling locations was greater for anglers using LIS than those not using LIS.

Conclusion
Results from this study suggest that the use of LIS may influence Blue Catfish angler perception and behavior more than catch.
Trauma and the perinatal period: A review of the theory and practice of trauma‐sensitive interactions for nurses and midwives
Authors: Isobel Sophie 
Published: September 2023

AbstractAimWith high rates of trauma in the population, known links between trauma and perinatal distress, and the intimate and close nature of the nursing and midwifery roles, ensuring awareness and understandings of trauma is crucial for guiding practice. This paper aims to explore the relationship of trauma to the perinatal period, based on theory and practice, to consider on how nurses and midwives can deliver trauma‐sensitive interactions.Design and MethodsThis discursive discussion draws on relevant research from the fields of trauma therapy, attachment theory and nursing and midwifery practice to consider elements of trauma‐sensitive practice in the perinatal period.ResultsNurses and midwives can foster safety for people who have experienced trauma through noticing and responding to triggers, supporting awareness of attachment and its relationships to trauma, undertaking psychosocial screening with care, supporting linearity and cohesion in narratives and developing collaborative care plans that maximise safety and agency. For nurses and midwives, understandings of the relationship between trauma, pregnancy, birth, early parenting and distress is crucial for effective care delivery.Delivering perinatal nursing or midwifery care of any kind, without universal trauma precautions risks reinforcing, misinterpreting or re‐enacting dynamics of trauma. To be trauma‐sensitive in this period requires nurses and midwives to have awareness of the dynamics of trauma in relation to pregnancy, birth and attachment.Implications for the Profession and/or Patient CareThis paper fills a gap in the translation of theory to practice for trauma‐sensitive care in the perinatal period, with a focus on the therapeutic relationship formed by nurses and midwives. The findings highlight that nurses and midwives can foster safety for people who have experienced trauma within their practice, when they hold a robust understanding of the relationship between trauma, pregnancy, birth, early parenting and distress.Patient or Public ContributionNo patient or public contribution.
Dummy template molecularly imprinted polymers as potential sorbents in the separation and purification of active compounds in natural products
Authors: Ariani Marisa Dwi , Zuhrotun Ade , Manesiotis Panagiotis , Hasanah Aliya Nur 
Published: September 2023

AbstractMolecular imprinting technology is a promising technique for separating, purifying, and enriching target compounds with high selectivity and sensitivity. The molecularly imprinted polymer (MIP) technique has developed rapidly in the separation and purification of chemical compounds and secondary metabolites of natural products. However, there are real challenges to the isolation of target compounds in natural products such as the unavailability of target compounds and high cost, so it is necessary to develop another approach to MIP synthesis. The dummy template is a solution to the unavailability of target compounds as it will produce a binding site that is specific enough for the target compound through covalent or non‐covalent bonds and the presence of the same functional groups between the target compound and the dummy will result in an interaction between the target compound and the binding site made using the dummy template. In addition, this dummy MIP (DMIP) is the best solution for overcoming the template leakage in traditional MIPs so that the DMIP technique is very good for removing and purifying compounds that are allergenic or toxic in natural product samples (high traceability). This review article will discuss the development of DMIPs in the separation and purification of compounds in natural products and the factors that affect their performance. Our discussion highlights the importance of selecting the right dummy template for optimal DMIP performance. This selection should be based on factors such as functional group similarity, being in the same bioactive compound group, and structural skeleton similarity. In addition, the selection and composition of other DMIP components can also affect the analytical performance of the DMIP.
Targeting the TWEAK–Fn14 pathway prevents dysfunction in cardiac calcium handling after acute kidney injury
Authors: Poveda Jonay , González‐Lafuente Laura , Vázquez‐Sánchez Sara , Mercado‐García Elisa , Rodríguez‐Sánchez Elena , García‐Consuegra Inés , Sanz Ana Belén , Segura Julián , Fernández‐Velasco María , Liaño Fernando , Ruilope Luis M , Ruiz‐Hurtado Gema 
Published: September 2023

AbstractHeart and kidney have a closely interrelated pathophysiology. Acute kidney injury (AKI) is associated with significantly increased rates of cardiovascular events, a relationship defined as cardiorenal syndrome type 3 (CRS3). The underlying mechanisms that trigger heart disease remain, however, unknown, particularly concerning the clinical impact of AKI on cardiac outcomes and overall mortality. Tumour necrosis factor‐like weak inducer of apoptosis (TWEAK) and its receptor fibroblast growth factor‐inducible 14 (Fn14) are independently involved in the pathogenesis of both heart and kidney failure, and recent studies have proposed TWEAK as a possible therapeutic target; however, its specific role in cardiac damage associated with CRS3 remains to be clarified. Firstly, we demonstrated in a retrospective longitudinal clinical study that soluble TWEAK plasma levels were a predictive biomarker of mortality in patients with AKI. Furthermore, the exogenous application of TWEAK to native ventricular cardiomyocytes induced relevant calcium (Ca2+) handling alterations. Next, we investigated the role of the TWEAK–Fn14 axis in cardiomyocyte function following renal ischaemia–reperfusion (I/R) injury in mice. We observed that TWEAK–Fn14 signalling was activated in the hearts of AKI mice. Mice also showed significantly altered intra‐cardiomyocyte Ca2+ handling and arrhythmogenic Ca2+ events through an impairment in sarcoplasmic reticulum Ca2+‐adenosine triphosphatase 2a pump (SERCA2a) and ryanodine receptor (RyR2) function. Administration of anti‐TWEAK antibody after reperfusion significantly improved alterations in Ca2+ cycling and arrhythmogenic events and prevented SERCA2a and RyR2 modifications. In conclusion, this study establishes the relevance of the TWEAK–Fn14 pathway in cardiac dysfunction linked to CRS3, both as a predictor of mortality in patients with AKI and as a Ca2+ mishandling inducer in cardiomyocytes, and highlights the cardioprotective benefits of TWEAK targeting in CRS3. © 2023 The Authors. The Journal of Pathology published by John Wiley & Sons Ltd on behalf of The Pathological Society of Great Britain and Ireland.
Hyperlipidemia in children and adolescents with acute lymphoblastic leukemia: A systematic review and meta‐analysis
Authors: Laumann Renate Dagsdottir , Pedersen Louise Lindkvist , Andrés‐Jensen Liv , Mølgaard Christian , Schmiegelow Kjeld , Frandsen Thomas Leth , Als‐Nielsen Bodil 
Published: September 2023

AbstractBackgroundThe established association between acute lymphoblastic leukemia (ALL) and hyperlipidemia has, in some studies, been linked to toxicities such as pancreatitis, thrombosis, and osteonecrosis. However, a systematic review investigating the incidence, management, and clinical implications of hyperlipidemia during childhood ALL treatment is lacking.ObjectivesSystematically assess the incidence of hyperlipidemia during ALL treatment, explore associations with risk factors and severe toxicities (osteonecrosis, thrombosis, and pancreatitis), and review prevalent management strategies.MethodsA systematic review was performed in accordance with the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) statement. Data synthesis was descriptive, and a meta‐analysis of hypertriglyceridemia and risk of severe toxicities was performed.ResultsWe included 13 studies with 3,425 patients. Hyperlipidemia incidence varied widely (6.7%‐85%) but with inconsistent definitions and screening strategies across studies. Evidence regarding risk factors was conflicting, but age (> 10 years) and treatment with asparaginase and glucocorticosteroids seem to be associated with hyperlipidemia. Hypertriglyceridemia (grade 3/4) increased the risk for osteonecrosis (odds ratio (OR): 4.27, 95% confidence interval (CI): 2.77‐6.61). No association could be established for pancreatitis (OR: 1.60, 95% CI: 0.53‐4.82) or thrombosis (OR: 2.45, 95% CI: 0.86‐7.01), but larger studies are needed to confirm this.ConclusionThe overall evidence of this systematic review is limited by the small number of studies and risk of bias. Our review suggests that hypertriglyceridemia increases the risk for osteonecrosis. However, larger studies are needed to explore the clinical implications of hyperlipidemia and randomized trials investigating hyperlipidemia management and its impact on severe toxicities.
Rearrangement and morphological transition of DNA on adsorbent templates of hydrocarbon/fluorocarbon phase‐separated monolayers
Authors: Maeda Momo , Shioda Yoshiki , Fujimori Atsuhiro 
Published: September 2023

AbstractA phase‐separated template prepared from a mixed monolayer of fluorinated long‐chain s‐triazine derivatives and comb copolymers containing s‐triazine rings was morphologically controlled by DNA adsorption. The adsorbed morphology of DNA was formed through a morphological transition process at the air/water interface rather than by maintaining the shape of the phase‐separated template. Dot‐like domains, circular domains, centrally protruding domains, network morphologies, and even co‐continuous surface morphologies of DNA were obtained. The phase‐separated monolayer used as a template depends on the mixed ratio of the fluorocarbon and hydrocarbon copolymer components, the copolymerization ratio of the hydrocarbon copolymers, and the chain length of the fluorinated long‐chain s‐triazine derivative, and various morphological transitions occur. The DNA introduced into the sub‐phase was selectively adsorbed onto the s‐triazine ring‐containing comb copolymer, and the adsorbed DNA assembly exhibited a morphological transition based on concerted interactions. Furthermore, by utilizing a fluorescent probe molecule, evidence of DNA morphogenesis itself was supported by its emission/quenching behavior.Highlights
Morphological control of the DNA assembly was attained.
Immobilization of DNA assemblies on phase‐separated templates was achieved.
Preparation of patterned templates was realized by copolymers a fluorinated derivative.
Adsorption of DNA to the diamino‐s‐triazine ring was achieved by hydrogen bonding.
A rearrangement of the DNA assemblies on the template was achieved.