bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALYSIS OF EXPRESSION OF VIRAL ANTIGENS AND CLINICAL AND MORPHOLOGICAL DATA IN ACUTE DECOMPENSATED HEART FAILURE WITH ISCHEMIC AND NON-ISCHEMIC ETIOLOGY
Authors: Ryabov Vyacheslav V. , Kruchinkina Ekaterina V. , Vyshlov Evgeny V. , Stepanov Ivan V. 
Published: February 2025

HighlightsPatients with IHD and complete coronary revascularization in history suffering from ADCHF should consider EMB to clarify the etiology of decompensation.According to the EMB results, concomitant myocarditis is diagnosed in the majority of patients with IHD and ADCHF.The results of immunohistochemistry indicate that patients with IHD and ADCHF often have antigen expression toward cardiotropic viruses. AbstractAim. To compare the clinical and morphological profile of patients with acute decompensated chronic heart failure (ADCHF) with ischemic and non-ischemic etiology with the following determination of the antigen expression toward cardiotropic viruses in myocardium.Methods. The observational study included 56 patients with ADCHF and LV EF <40%, the patients were divided into 2 groups: patients with ischemic heart disease (IHD) after complete coronary revascularization (n = 26) and patients without IHD (n = 30). All patients underwent standard clinical, instrumental and laboratory examinations (invasive coronary angiography and endomyocardial biopsy (EMB) with morphological analysis and determination of the antigen expression toward cardiotropic viruses).Results. Patients with ischemic ADCHF presented with fewer rates of shortness of breath during hospitalization compared with patients with non-ischemic ADCHF (12 vs 53%, p = 0.001), fewer rates of wheezing (54 vs 74%, p = 0.014), lower heart rhythm (76 vs 90, p = 0.047) and lower respiratory rate (18.5 vs 22, p = 0.031), lower N-terminal prohormone of brain natriuretic peptide levels (403.1 vs 964.0 pg/mL, p = 0.019), and lower incidence of diffuse LV hypokinesis (58 vs 87%, p = 0.002), but ischemic ADCHF patients also presented with higher rates of edema of the lower extremities (46 vs 20%, p = 0.037) and atrioventricular blockade of varying degree (35 vs 7%, p<0.05). According to EMB data, concomitant myocarditis was diagnosed in 69% of patients with ischemic ADCHF and in 80% of patients with non-ischemic ADCHF. Patients in both groups were more likely to present with the expression of enterovirus antigens (77 and 80%), and less likely to present with the expression of human herpesvirus 6 (HHV-6, 50 and 53%) and Epstein-Barr virus antigens (EBV, 23 and 20%), respectively (there were no statistically significant differences).Conclusions. Patients with ischemic ADCHF had less pronounced decompensation compared with patients with non-ischemic ADCHF. Patients with ischemic ADCHF have concomitant myocarditis in 69% of cases according to EMB. Enterovirus, HHV-6 and EBV antigens were the most commonly expressed antigens. Thus, the majority of patients with IHD and complete coronary revascularization in history had ADCHF due to a combination of IHD and viral myocarditis.
KEY TECHNICAL ASPECTS AND RESULTS OF RADICAL CORRECTION OF THE TETRALOGY OF FALLOT IN CHILDREN AFTER RIGHT VENTRICULAR OUTFLOW TRACT STENTING: EMPHASIS ON THE PULMONARY ARTERY VALVE
Authors: Lyapin Anton A. 
Published: February 2025

HighlightsThe review describes the outcomes of right ventricular outflow tract stenting in children with the tetralogy of Fallot.The features of stent explantation and further functioning of the pulmonary artery valve after surgery are analyzed. Aim. To analyze the technical aspects related to the explantation of stents from right ventricular outflow tract (RVOT) and repair of the pulmonary artery valve during radical correction (RC) of tetralogy of Fallot (TOF), and the results of subsequent surgical treatment of these patients.Methods. The study included 25 children with a cyanotic TOF who received a two-stage correction of CHD (stage 1 – RVOT stenting, stage 2 – RC of TOF).Results. Shortly after RVOT stenting, we noted positive changes in the condition of children. The median of arterial oxygen saturation rose from 80% to 95%, the gradient on RVOT decreased from 72 to 53 mmHg. After 3 months children underwent RC of TOF. Patients received palliative care in the form of RVOT stenting with a low complication rate, only 4% of patients had a fatal outcome. During RC of TOF, there were no technical difficulties regarding explantation of the stent from RVOT. The thirty-day survival rate was 96%. During RC 16% of patients avoided transannular repair procedure.Conclusion. The patients were provided with effective palliative care such as RVOT stenting, which was reflected by improved oxygenation after the procedure and optimal growth of the pulmonary arteria and left ventricle by the time of RC. There were no technical difficulties regarding the explantation of the stent from RVOT during RC.
INDICATIONS FOR VALVE-SPARING AND RECONSTRUCTIVE AORTIC ROOT SURGERY: A RETROSPECTIVE COHORT STUDY
Authors: Komarov Roman N. , Vasalatiy Ilya M. , Tkachev Maxim I. , Isaev Ruslan M. , Shumakhova Ariana O. , Murylev Daniil V. , Solenova Elena Y. , Rashidova Aminat M. 
Published: February 2025

HighlightsThe review presents the results of valve-sparing and reconstructive aortic root surgeries. The results of the analysis of patients` data can help specialists to compare and develop novel approaches to the treatment of patients with aortic root diseases. The presented “Russian conduit” procedure developed by the authors is an option for treatment of the aortic valve and aortic root defects. Aim. To develop an optimal technique for surgical treatment of aortic root pathologies. The review presents data on modern surgical approaches in the management of the disease, including the Bentall-De Bono procedure, “classic” and “modified” David procedures, the “Russian Conduit” procedure, and the Ross procedure.Methods. The retrospective study involved 183 patients who underwent surgeries for aortic root pathologies. Patients were divided into five groups based on the surgical techniques. Clinical and laboratory data were evaluated in the mid-term postoperative period. Statistical analysis included comparative methods using various criteria and tests.Results. The David procedure was advantageous over the Bentall-De Bono procedure for patients with intact aortic valve leaflets. The “Russian conduit” procedure demonstrated safety and durability comparable to the classic David procedure, along with good hemodynamic performance. There was a higher frequency of residual aortic regurgitation following leaflet repair within the “modified” David procedure.Conclusion. The results confirm that techniques using autologous tissues, such as the “Russian conduit” and “Protected Ross” are effective and safe alternatives to traditional replacement methods. The David procedure remains preferable for patients without leaflet damage, while procedures involving complete replacement are advisable for patients with severe valve pathology.
INFLUENCE OF PREVIOUS CATHETER ABLATIONS ON THE EFFICACY OF THORACOSCOPIC TREATMENT OF ATRIAL FIBRILLATION
Authors: Strebkova Elizaveta D. , Artyukhina Elena A. , Kadirova Madina , Revishvili Amiran S. 
Published: February 2025

HighlightsDespite the widespread use of thoracoscopic ablations in the treatment of atrial fibrillation, accurate predictors of recurrent arrhythmia have not been established, therefore, the effectiveness of this procedure varies significantly (from 38 to 83%). According to clinical guidelines, thoracoscopic ablation should be considered in patients after primary catheter ablation. Several studies have noted that patients with a catheter ablation in history have a significantly higher risk of recurrent atrial fibrillation after thoracoscopic ablation compared with patients without catheter ablation in the 5-year follow-up period. However, our study results indicated similar prevalence of recurrent arrhythmia in patients with and without catheter ablation. Taking into account all of the above, we have evaluated the impact of previous catheter ablations on the effectiveness of thoracoscopic ablation of atrial fibrillation in the long-term follow-up period. Aim. To assess the impact of failed pulmonary vein catheter ablation (CA) on the efficacy and safety of thoracoscopic ablation (TSA) in the long-term follow-up period.Material and Methods. “Box lesion” TSA with left atrial auricle (LAA) exclusion was performed in 47 patients with CA in history and 103 patients without CA. The procedure was considered effective in the absence on 24-h HM ECG of any atrial tachyarrhythmia of more than 30 seconds duration recorded at the examination checkpoints. Results. The efficiency of TSA in the group with CA was 61,5% and 77,5% in the group without CA, with a mean follow-up period of 2,6 ± 0,83 years. Univariate and multivariate Cox proportional hazards analyses showed that prior CA statistically significantly increased the risks of atrial tachyarrhythmia recurrence by 1,936-fold (95% CI 1,931–4,026, p = 0,037) and 1,917-fold (95% CI 1,913–4,098, p = 0,042), respectively. Conclusion. The study results revealed that previous unsuccessful pulmonary vein CA may reduce the effectiveness of TSA in the long-term follow-up period. However, this topic requires further research involving multivariate analysis on a larger cohort of patients.
The Use of Blockchain Technologies in Transport Transactions
Authors: Anisimov A. V. 
Published: February 2025

The article is devoted to the implementation of blockchain technology in transport transactions and the impact of this technology on the features of concluding and executing transactions in the transport sector. Blockchain technology is a key element of smart contracts, as a type of electronic transactions in the transport sector. Blockchain technology provides new opportunities for the security of concluding transactions, but the key issue in regulating such transactions is the identification of transaction subjects, as well as data protection from unlawful encroachment. A smart contract allows the full use of artificial intelligence technologies in the transport sector both for concluding and monitoring the execution of a transaction.The problem with regulatory frameworks is that most countries do not have specific regulations, but allow the use of blockchain-based tools, such as smart contracts and electronic bills of lading. However, recent changes to digital asset legislation, allowing for settlements in cryptocurrency, indicate a trend towards permissive regulation of blockchain technology, which will lead to greater adoption of this technology in the transport sector.
Development of Norms on the Objects of Law in the Codifications of Civil Legislation
Authors: Dolinskaya V. V. 
Published: February 2025

A comparative legal analysis of the norms of the three codifications of civil legislation on the issues of objects has been carried out. The influence of various doctrinal concepts on civil codes is revealed. The consequences of mixing the concepts of “things” and “property” are shown. The advantages and disadvantages of digital objects in the system of property rights are highlighted. Defects have been identified in the modern consolidation of the classification of objects by turnover. The classification of objects according to their intended purpose and legal regime is considered. The disadvantages of the legal division of objects into movable and immovable, the “blurring” of the latter category are identified. Attention is paid to the impact of the development of economic activities on the objects of civil rights. The connection of intangible benefits in the system of objects of rights with the tendency of socialization of private law is shown. The differentiation of Results of intellectual activity and rights to them is positively assessed, and the displacement of the classical term “creative activity” by the category of “intellectual activity” is criticized. The classification of civil legal relations according to the role of such an object as information is proposed.Conclusions are drawn about the progressive development of civil law and legislation, the expansion of the range of objects of law in the codifications of civil legislation, and the improvement of norms on their legal regime. Some shortcomings of legal regulation have been identified. Targeted doctrinal studies and preliminary testing of new legal norms on pilot projects are proposed.
Histiocitosis cefálica benigna. a propósito de un caso
Authors: Castillo Botero Alejandro , Alarcón Soldevilla Fernando , Campoy Carreño Celia , García Almazán Lucía , Torrent García Marina , Ortiz González Ana 
Published: February 2025

La histiocitosis cefálica benigna es una enfermedad rara perteneciente a las histiocitosis cutáneas y mucocutáneas. El reconocimiento de esta patología es importante para poder informar a la familia del carácter benigno y la naturaleza auto resolutiva. Aunque no requiere tratamiento, es importante realizar seguimiento para evaluar la evolución de las lesiones cutáneas. Se presenta el caso de un paciente varón de 2 años con pápulas amarillo-anaranjadas, asintomáticas, en el rostro, sin sintomatología acompañante. Se realizó una biopsia con análisis histopatológico e inmunohistoquímico. Tras correlación clínico-patológica, se establece el diagnóstico de histiocitosis cefálica benigna. Durante el seguimiento se observó la estabilidad y el carácter involutivo de las lesiones.
Potential Biases in Mixed-Effects Ground-Motion Models and Variance Components Due to Uncertainty in Random Effects
Authors: Kuehn Nicolas M. , Campbell Kenneth W. , Bozorgnia Yousef 
Published: February 2025

ABSTRACT
Empirical ground-motion models are typically estimated via mixed-effects regression, to account for correlation between records from the same event or from the same site or station. Estimated values of the random effects are often used in further analyses, for example, to develop additional submodels or to investigate physical characteristics of individual events or sites. Such analyses often do not account for uncertainty in the random effects. Using simulations, we show that neglecting these uncertainties can lead to a variety of biases, such as underestimation of variances or biased scaling with predictor variables. We demonstrate that these biases can often be overcome by estimating more complex (e.g., Bayesian) models on the total residuals of a mixed-effects regression.
Apresentação
Authors: Diniz Dilma Castelo Branco , Pinto Sabrina Sedlmayer , Bianchet Sandra Maria Gualberto Braga 
Published: February 2025

Os ensaios que compõem este número do periódico Em Tese apresentam um amplo e diversificado panorama da produção acadêmica dos pós-graduados do programa de Pós-Graduação em Letras — Estudos Literários — da Faculdade de Letras da UFMG. Atualmente, o programa oferece cursos de Doutorado em Literatura Comparada e em Literatura Brasileira, além dos cursos de Mestrado em Teoria Literária, Literatura Brasileira, Literaturas de Expressão Inglesa e Estudos Clássicos. Os textos aqui reunidos se vinculam às seguintes linhas de pesquisa: Poéticas da Modernidade; Literatura e Psicanálise; Literatura e outros Sistemas Semióticos; Teorias do Comparativismo; Literatura e Expressão da Alteridade; Literatura, História e Memória Cultural. Entre os autores brasileiros estudados, destacam-se, entre outros, Machado de Assis, Clarice Lispector, Guimarães Rosa, Nelson Rodrigues, Aníbal Machado, Mário de Andrade e Modesto Carone. E, entre os estrangeiros, Margaret Atwood, Angela Carter, Toni Morrison, Umberto Eco, Antoine Compagnon, Eça de Queirós, Al Berto, Fernando Pessoa, entre outros. A divulgação desses trabalhos contribuirá, certamente, para ampliar os debates e as pesquisas de Pós-Graduação no Brasil contemporâneo. Dilma Castelo Branco Diniz Sabrina Sedlmayer Pinto Sandra Maria Gualberto Braga Bianchet
Investigating the impact of online learning on mathematical preparedness of first-year engineering students in Eastern Visayas, Philippines
Authors: Gomba Felisa , Perante Wenceslao 
Published: February 2025

This study investigated the effects of the sudden shift to online education during the COVID-19 pandemic on the mathematical preparedness of first-year engineering students. This study compared the mathematical readiness of students who graduated from Senior High School (SHS) K-12 programs in 2020 (face-to-face education) and graduates of SHS-2021 (online education) using a College Math Readiness Assessment (CMRA), an assessment tool for college level mathematics. This research used a quantitative-comparative design to investigate the 271 participants (156 from the SHS-2020 cohort and 115 from the SHS-2021 cohort). The findings revealed that 55% of the SHS-2021(online) and 48% of the SHS-2020 (face-to-face) based on their CMRA scores were classified as mathematically college-ready (MCR) for engineering programs. Although the online education cohort had a slightly higher percentage of MCR students, the difference in mean scores between the two groups was not statistically significant (t (210) = 1.97, p =0.15). However, the SHS-2021 cohort showed a wider distribution of scores with higher percentages of students in both the 'excellent' and 'poor' categories than the SHS-2020 cohort. The study concludes that while online learning during the pandemic did not significantly hinder overall mathematical preparedness for engineering programs, the variability in performance among online learners highlights the need for targeted support and interventions to ensure equitable learning experiences and outcomes for all students.
Comparing two psychometric approaches: The case of item analysis for a classroom test in mathematics
Authors: Garcia Mark Lester B , Santos Kevin Carl P , Vistro-Yu Catherine P 
Published: February 2025

Multiple-choice and constructed-response item formats are widely used in Philippine classrooms where tests are primarily summative. Conducting item analysis provides teachers the professional possibility to independently improve their test items while also allowing them to make informed decisions about test improvement and ensure that their assessments provide meaningful scores. Comparisons of item analysis approaches have been extensively used in standardized tests but not so much in small-scale testing such as classroom assessments. Hence, this research reports an empirical study where a summative test for classroom use is analyzed using psychometric techniques from the Classical Test Theory (CTT) and the Item Response Theory (IRT). This study employs an action research design where the primary author being a teaching practitioner-researcher, reports how an item analysis of his teacher-made summative test was conducted to improve the test items. Results from this study show that interpretations of the item parameter estimates from both psychometric approaches, CTT and IRT agree on most of the recommendations for the items. The items where the two approaches provide contrasting recommendations call for a further qualitative evaluation of the flagged items putting the teacher in a judicious position to discern which recommendations to follow regarding the concerned items. In the context of this study, an example of a guiding insight in deciding would be reflecting on the learning objectives measured by the test and the context in which the test was created.
Developing principles and steps for integrating bioinformatics into teaching for pedagogical university students: A case study in Vietnam
Authors: Nguyen Hang Thi , Nguyen Lan Thi Ngoc , Nguyen Quan Huu , Tu Tan Quang , Chu Mau Hoang 
Published: February 2025

The main objective of this study is to develop the principles and methods for integrating bioinformatics into biology teaching. The study started with analyzing the high school biology curriculum, a survey on bioinformatics knowledge of teachers and pedagogical university students, a survey of teacher training curricula of pedagogical universities and education faculties and proposed principles and steps for integrating bioinformatics into biology teaching. The research results proposed six basic principles and a four-step process to guide pedagogical university students in integrating bioinformatics into biology teaching. The main principles include being simple, identifiable and appropriate for students, being compatible with biological knowledge content and bioinformatics, breaking down the knowledge module for analysis and empowering, personalizing students creating a model for analysis on paper before utilizing a computer and producing particularly good products related to bioinformatics. A four-step process, including selecting knowledge topics suitable for bioinformatics applications, dividing the topic into small knowledge modules, data analysis using bioinformatics, and creating bioinformatics products. The findings of this study provide valuable insights that show that integrating bioinformatics into high school biology teaching is necessary. Applying principles and methods of integrating bioinformatics into teaching promises to improve the quality of biology teaching and promote STEM education in Vietnam and developing countries.
Lipoma preperitoneal: reporte de caso
Authors: Pesántez Brito Ismael Francisco , Gonzalez Barros Daliana Estefania 
Published: February 2025

Introducción: los lipomas son tumores benignos que pueden presentarse en cualquier parte del cuerpo, aunque su localización preperitoneal es rara y poco frecuente.Caso clínico: mujer de 65 años con dolor abdominal intermitente, tipo punzante, en el flanco y el hipocondrio derecho, de 20 días de evolución. Antecedente de colecistectomía laparoscópica nueve meses antes, durante la cual se observó una masa en el peritoneo parietal del hipocondrio derecho. Se solicitó una tomografía simple y contrastada de abdomen, que evidenció una masa hipodensa con características de atenuación de grasa, localizada entre el músculo transverso abdominal derecho y el borde externo del hígado, compatible con lipoma. La extracción se realizó por vía laparoscópica sin complicaciones y con una evolución favorable.
Conclusión: los lipomas preperitoneales son raros y poco frecuentes. La cirugía laparoscópica permitió una resección completa del lipoma y una recuperación rápida de la paciente.
STRATEGI PEMBENTUKAN KARAKTER RELIGIUS ANAK ASUH PANTI PELAYANAN SOSIAL ANAK (PPSA) KASIH MESRA
Authors: Amania Fatimah Nila 
Published: February 2025

This research was carried out because it was motivated by cases of many character abuses committed by children, especially children who had disadvantaged family backgrounds. Whether it is the absence of parents, or economic problems that make children less concerned about character formation, especially religious character. The aim of this research is to describe the formation of the religious character of foster children at the Kasih Mesra Demak Children's Social Services Home (PPSA). In this research, the type of research used is descriptive qualitative field research. This research uses data collection methods in the form of interviews, observation, documentation and questionnaires. Based on the research that has been carried out, the researchers obtained the results that the religious character of foster children is formed through providing understanding through guidance, the example of orphanage caregivers, and through scheduled habituation activities. Activities that focus on methods of providing understanding can be seen in the activities of providing guidance, namely: biological, psychological, social and religious guidance. Activities that focus on the habituation method applied at PPSA Kasih Mesra Demak are: congregational prayers, reciting the Koran, gatherings and praying together, as well as all activities that have been carried out. The exemplary method used to shape the religious character of foster children is, imitating the daily behavior of caregivers and PPSA employees, for example, discipline during prayer times and teaching children the Koran, honesty in providing children's rights, fairness in caring for children, and tawadhu' in get along..