bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prolonged Sitting and Low Back Pain in Dental Practice: A Complex Relationship Explored in Jakarta
Authors: Hendarmin Laifa Annisa , Zaki Achmad , Andini Dela , Mardjikoen Bisatyo , Rufaidah Melia Fatrani , Thaiyibah Nazaratun 
Published: January 2025

Aims & Background
Low back pain (LBP) is the leading cause of disability globally, affecting approximately 619 million people in 2020, with projections suggesting that this number will rise to 843 million by 2050. LBP accounts for a significant proportion of years lived with disability (YLDs) worldwide. Dentists are particularly vulnerable to LBP due to the prolonged static and non-ergonomic postures required to access small areas within the oral cavity, which often results in extended examination times. Poor posture, such as prolonged standing or sitting, is a recognized risk factor for developing LBP. This study aims to examine the relationship between prolonged sitting duration during dental practice and the prevalence of LBP among dentists in Jakarta.

Materials and Methods
A cross-sectional study was performed involving 106 dentists, chosen through quota sampling based on specific inclusion and exclusion criteria. Data were gathered using a standardized questionnaire and the Roland-Morris Disability Questionnaire (RMQ) to assess functional impairment due to LBP. The Chi-Square test was used to analyse the association between sitting duration and LBP complaints.

Results
The results showed no significant association between prolonged sitting duration (p = 0.617) or physical activity (p = 0.662) and the prevalence of LBP. However, age was significantly associated with LBP prevalence (p = 0.008), with dentists aged 46–65 years reporting a higher prevalence. Additionally, years of practice approached statistical significance (p = 0.057), suggesting a potential link between prolonged occupational exposure and the risk of LBP. Despite the lack of significance for sitting duration and physical activity, the findings highlight the importance of considering other factors, such as chair design, posture, movement patterns, and the cumulative impact of years of practice, that may contribute to LBP in this professional group.

Conclusion
Age and years of practice are important factors contributing to the prevalence of LBP among dentists, emphasizing the impact of age-related changes and prolonged occupational strain. While sitting duration and physical activity showed no significant association, the findings underscore the need for targeted ergonomic interventions and preventative strategies tailored to the specific demands of dental practice.
Adherence to Radiation Protection Principles in the Clinical Environment among Anesthesia and Operating Room Nursing Students: Implications for Educational Interventions
Authors: Ghasemi Sina , Khosravi Hossein , Imani Behzad , Shabani Naeeme 
Published: January 2025

Background
The increasing use of ionizing radiation in clinical environments, particularly during surgeries such as orthopedics and neurosurgery, has heightened concerns about the potential health risks associated with this type of radiation. This issue is particularly relevant for nursing students undergoing training in operating room settings, where they are frequently exposed to various sources of radiation. To effectively implement radiation protection principles, it is crucial to evaluate the knowledge and attitudes of the students toward ionizing radiation. Understanding their level of awareness and beliefs about radiation safety will inform the development of targeted training programs aimed at minimizing exposure and enhancing safety in clinical environments.

Objective
This study aimed to investigate the level of knowledge, attitudes, and performance of 8th-semester undergraduate anesthesia and operating room nursing students toward radiation protection principles.

Methods
This cross-sectional study was conducted at the Hamadan University of Medical Sciences in 2024. In this study, students were selected via the census sampling method. The data related to the study were collected from valid questionnaires concerning the participants’ level of knowledge, attitudes, and performance toward ionizing radiation. The data analysis was also conducted at the descriptive and inferential statistics level via SPSS version 16 software.

Results
The knowledge, attitudes, and performance of the students in both fields were inadequate compared to the ideal standards. Additionally, the mean attitude score toward protective principles was significantly greater among operating room nursing students than anesthesia nursing students (p-value = 0.023). Furthermore, a positive and significant correlation was found between students' Grade Point Average (GPA) and their scores on knowledge and attitudes toward protective principles (r = 0.449, p-value = 0.000 and r = 0.648, p-value = 0.000, respectively).

Conclusion
This study revealed that the level of knowledge among students regarding ionizing radiation is lower than the desired standards for ensuring safety in clinical environments. As a result, it is essential to implement targeted training courses to enhance students' understanding of the risks associated with ionizing radiation.
Synthesis and Characterization of Thioamidoalkyl Fluorescein Analogs for Antibacterial Activity and Molecular Docking Analyses
Authors: Kousar Shazia , Tabassum Maryam , Qaid Saif Mabkhot , Mohamed Yusof Nur Intan Saidaah , Mohd Fauzi Fazlin , Ali Shah Syed Adnan , Shahid Muhammad , Irfan Madiha , Monawar Ayesha , Bukhari Syed Waqas , Mudassir Muhammad Ahmad 
Published: January 2025

Aims and Objectives:
The study aimed to employ one-pot solvent-free boric acid-catalyzed
multicomponent reactions (MCRs) to synthesize bioactive thioamidoalkyl fluorescein analogs.
The study aimed to introduce a facile and environmentally sustainable strategy for efficiently
producing alternate potent bioactivity agents.

Background:
Population growth trends, limited efficacy and side effects of available medicine, and
new challenges like antibiotic resistance have led to the urgent need for more and better pharmaceuticals
and a notable increase in drug development. The global health demands and significant
medicinal value of thioamidoalkyl compounds prompted synthesizing new fluorescein-based thioamidoalkyl
derivatives to explore their prospective biomedical potential.

Methods:
To prepare thioamidoalkyl fluorescein analogs, a solvent-free three-component reaction
of fluorescein with aryl aldehydes and thiobenzamide catalyzed by boric acid was used. The antibacterial
potentials of thioamidoalkyl fluorescein analogs against Escherichia coli (E. coli) bacteria
were analyzed in terms of half-maximal inhibitory concentration (IC50). Moreover, molecular docking
experiments explored the binding affinities and possible interaction mechanisms between newly
synthesized analogs and active sites of E. coli adhesion protein FimH.

Results:
FTIR, 1H, and 13C NMR results verified the successful formation of all analogs. The
experimental and theoretical antibacterial activity results confirmed that the compound M-11 is
relatively more potent against E. coli based on lower IC50 values of 54.14 nM and binding energy
value of ‒6.30 kcal/mol (comparable to ‒6.70 kcal/mol of reference ligand) probably because of
unique structure and strong binding affinities for target protein structure.

Conclusion:
The findings demonstrated the potential of the currently employed synthetic approach
to produce new analogs with decent yields facilely. Interestingly, the M-11 compound proved to be
an excellent prospective source of antibiotic drugs based on both experimental and computational
analyses.
Impact of Green Synthesis of Ag-nanoparticle Using Extracellular
Manganese Peroxidase on Different Dye Degradation
Authors: Hoque Rohida Amin , Yadav Meera 
Published: January 2025

Introduction:
The study explores the biosynthesis of silver nanoparticles (AgNPs) using
extracellular manganese peroxidase enzyme from Trichoderma parestonica. The synthesis was optimized
at a 1:1 enzyme and silver nitrate ratio, pH 12, shaking process, and 48-hour synthesis
period. The AgNPs were characterized using spectroscopic and microscopic techniques, showing
absorbance in UV-spectroscopy between 410-450 nm due to Surface Plasmon Resonance (SPR).

Method:
The stabilization of extracellular manganese peroxidase with the nanoparticles through
capping was observed by Fourier Transform Infrared Spectroscopy (FT-IR). The spherical shape
of the AgNPs, with an average size of 69.09 nm, is confirmed by the Field Emission Scanning
Electron Microscopy (FESEM) study. The size of the nanoparticles was also determined by Dynamic
Light Scattering (DLS) to be 75.99 nm. When synthesized AgNPs were used to decolorize
Alizarin red S (ARS), Methylene Blue (MB), and Methyl Orange (MO) in the presence of sodium
borohydride reducing agent, the results showed that, within 20 minutes, 90% of 0.1mM ARS, MB,
and 75% 0.1mM MO were degraded.

Result:
This study demonstrated the potential of AgNPs synthesized from MnP enzyme in nanoremediation
projects, offering a sustainable solution to the problems and issues of dye-induced
wastewater pollution and fostering environmental conservation.

Conclusion:
Enzymes are being studied in nanotechnology, leading to the development of enzyme
nanoparticles, which can be utilized in various fields like biosensors agriculture, drug delivery, and
bioremediation.

other:
Key-words: Manganese peroxidase; Silver nanoparticles; Dye decolorization; Alizarin red S, Methylene blue, Methyl orange
A Deep Ensemble Learning Approach for Automatic AD Detection
Authors: A.G. Balamurugan , N. Gomathi 
Published: January 2025

Introduction:
Early detection of Alzheimer's disease (AD) is crucial due to its rising
prevalence and the economic burdens it imposes on individuals and society. This study aimed to
propose a technique for the early detection of AD using MRI scans.

Method:
The methodology involved collecting data, preparing the data, creating both single and
combined models, assessing with ADNI data, and confirming with additional datasets. The approach
was chosen by comparing various scenarios. The top six individual ConvNet-based classifiers
were combined to form the ensemble model. The evaluation showed high accuracy rates
across various classification groups. Validation of additional data showed impressive accuracy,
exceeding results from numerous previous studies and aligning with others.

Results:
Although ensemble methods outperformed individual models, there were no notable distinctions
among different ensemble approaches. The ensemble model was constructed using the
top six individual ConvNet-based classifiers in deep learning (DL), achieving high accuracy rates
across various classification categories: 98.66% for Normal control | AD, 96.56% for Normal control
| Early MCI, 94.41%

Conclusion:
Early MCI/Late MCI, 99.96% for Late MCI | AD, 94.19% for four-way classification,
and 94.93% for three-way classification. Validation results underscored the limited effectiveness
of individual models in practical settings, contrasting with the promising outcomes of the
ensemble method.
Nicotine Exposure in Pregnancy and its Link to Autism Spectrum Disorder: A Review on Evidence, Biological Pathways, and Directions for Future Research in Neurological Disorders
Authors: Ahmad Iftakhar , Al Noman Abdullah , Datta Monty , Parves Md Maruf , Pathak Rashmi , Sharma Himanshu 
Published: January 2025

Abstract:
Pregnancy-related smoking and nicotine exposure by the mother can
impact the developing brain of the baby and increase the likelihood that the kid
will have autism or other neurodevelopmental disorders. However, conflicting
epidemiological evidence links prenatal nicotine exposure to ASD, and the
molecular processes involved remain unknown. The data on the impact of the
mother smoking during pregnancy on the development of the fetal brain and the
likelihood of neurodevelopmental disorders such as ASD are thoroughly reviewed
in this paper. Nicotine can enter the developing tissue of the baby
through the placenta and build up there. In the developing brain, it attaches itself
to nicotinic receptors, impairing chemical equilibrium, growth, communication,
and cell division, all essential for the passage of messages between neurons
throughout crucial developmental stages. There is conflicting evidence, even
though some human studies indicate that smoking during pregnancy raises the
risk that the fetus will develop ASD. Some basic biological processes that have
been proposed include damage to the placenta, oxygen deprivation, genetic
changes, and abnormalities in brain chemistry, including dopamine. Overall, the
data now available indicates that smoking during pregnancy is detrimental to the
developing brain of the fetus. Consequently, abstaining from smoking and nicotine
during pregnancy can reduce the likelihood that the fetus would experience
any neurological disorders, including ASD. To fully comprehend the molecular
mechanisms involved and establish definitive links between prenatal nicotine exposure
and ASD, further studies are still required.
Pengaruh Product Placement, Sponsor Event Fit, Dan Brand Exposure Terhadap Brand Awareness
Authors: Arthana Gilang Hans , Isharina Ikhtiara Kaideni 
Published: January 2025

The rapid development of the food and beverage industry has increasingly business competition. The increasing number of products with various brands appearing on the market require companies to recognize factors affecting brand awareness in order to win the competition. The purpose of this research is to examine the effect of product placement, sponsor event fit, and brand exposure toward the brand awareness Teh Kotak (study on Indonesian Idol XII audience in East Java.) This study adopts an explanatory research design with a quantitative approach. The sample size used was 160 respondents. Sampling used purposive sampling technique with the characteristics of a minimum age of 17 years, domiciled in East Java, and had watched advertising Teh Kotak on Indonesian Idol XII TV shows. The data analysis technique employed in this study was multiple linear regression and processed using the IBM SPSS program version 25. This study finds that product placement positively and significantly influences brand awareness, sponsor event fit positively and significantly influences brand awareness, and brand exposure positively and significantly influences brand awareness.

Abstrak
Pesatnya perkembangan industri makanan dan minuman menyebabkan persaingan bisnis semakin ketat. Semakin bertambahnya jumlah produk dengan berbagai merek yang muncul di pasar membuat perusahaan perlu untuk mempertimbangkan faktor faktor yang dapat mempengaruhi brand awareness untuk memenangkan persaingan. Penelitian ini bertujuan untuk mengetahui pengaruh product placement, sponsor event fit dan brand exposure terhadap brand awareness Teh Kotak (studi pada penonton Indonesian Idol XII di Jawa Timur). Jenis penelitian ini adalah explanatory research dengan metode kuantitatif. Ukuran sampel yang digunakan sebanyak 160 responden, Pengambilan sampel menggunakan teknik purposive sampling dengan kriteria responden berusia minimal 17 tahun, berdomisili di Jawa Timur, dan pernah melihat iklan Teh Kotak dalam tayangan Indonesian Idol XII. Teknik analisis data menggunakan analisis regresi linier berganda dan diolah menggunakan bantuan program IBM SPSS versi 25. Hasil Penelitian ini menunjukkan bahwa (1) product placement berpengaruh positif dan signifikan terhadap brand awareness, (2) sponsor event fit berpengaruh positif dan signifikan terhadap brand awareness, dan (3) brand exposure berpengaruh positif dan signifikan terhadap brand awareness.
Time and The Diary in Captivity, a Case Study: The Diary of Fela Szeps (1942-1944)
Authors: Ben-Amos Batsheva 
Published: January 2025

When the diarist is free from imminent danger, and has reasonable flexibility in managing a daily routine, clock-and-calendar time helps in organizing the individual’s chosen social roles and responsibilities as well as their private interests, all of which are the building blocks of personal identity. Daily objective time is not bestowed as such with a symbolic meaning but is taken for granted as a point of reference.
In concentration camps, gulags, and prisons, freedom of movement and choice — contact with the outside world, access to information, interactions with others, quality of food and hygiene, privacy — are controlled by the captors. Hence, the inmate’s time and space perception are transformed.
As a literary genre, the diary chains subjective time in cages of objective time, and the two are in a constant state of collision. In this article I analyze the vicissitudes in time perception and a personal modification of public spaces in a diary written by 24-year-old Warsaw University student Fela Szeps, (1918–1945), from the Polish town of Dąbrowa Górnicza. She kept a clandestine diary between April 1942 and November 1944 in the Grünberg forced-labor camp in Silesia, Poland.
PENGARUH MODEL PEMBELAJARAN PROBLEM BASED LEARNING BERBANTUAN GEOGEBRA TERHADAP PEMAHAMAN KONSEP MATEMATIS DAN KEMAMPUAN BERPIKIR KRITIS SISWA PADA MATERI BANGUN RUANG SISI LENGKUNG
Authors: Khoirunisa Sania Azzura , Susanti Mathilda 
Published: January 2025

Penelitian ini bertujuan untuk mengetahui pengaruh model pembelajaran Problem Based Learning berbantuan media Geogebra terhadap pemahaman konsep matematis dan kemampuan berpikir kritis siswa pada materi bangun ruang sisi lengkung kelas VII SMP. Jenis penelitian ini adalah quasi eksperimen dengan desain pretest-posttest control group. Populasi dalam penelitian ini adalah siswa kelas VII SMP Negeri 16 Yogyakarta dengan Kelas VII C sebagai kelas eksperimen dan kelas VII A sebagai kelas kontrol. Untuk menarik kesimpulan data dianalisis menggunakaan uji T2 Hotelling dan uji Independent Sample T-Test. Hasil dari penelitian ini (1) Model pembelajaran Problem Based Learning berbantuan Geogebra berpengaruh terhadap pemahaman konsep matematis dan kemampuan berpikir kritis, (2) Model pembelajaran Problem Based Learning berbantuan Geogebra berpengaruh terhadap pemahaman konsep matematis siswa, (3) Model pembelajaran Problem Based Learning berbantuan Geogebra berpengaruh terhadap kemampuan berpikir kritis siswa.
Analisis Penggunaan Berbagai Jenis Substrat untuk Pertumbuhan Caulerpa racemose Pada Pembudidayaan di Tambak Pasang Surut
Authors: Yanti Ros Erni , Rahim Andi Rahmad , Farikhah Farikhah 
Published: January 2025

Substrat merupakan salah satu faktor penting untuk kehidupan dan pertumbuhan C. racemosa, namun saat ini belum ada studi substrat terbaik di tambak pasang surut. Tujuan penelitian ini adalah menganalisis pertumbuhan Caulerpa racemosa yang dibudidayakan di tambak pasang surut dengan penggunaan jenis dan komposisi substrat yang berbeda. Metode penelitian ini adalah eksperimental dengan Rancangan Acak Lengkap (RAL). Lima perlakuan di penelitian ini yaitu (A) lumpur 100%, (B) lumpur 50% : pecahan karang 50%, (C) lumpur 50% : cangkang tiram 50%, (D) lumpur 50% : pasir 50%, (E) lumpur 50% : pecahan karang 20%, : cangkang tiram 20% : pasir 10%. Variabel penelitian ini meliputi bobot mutlak, specific growt rate (SGR), panjang mutlak stolon, panjang dan lebar fronds, dan jumlah mutlak rizoid. Parameter kualitas air meliputi suhu, salinitas, kecerahan, kadar amonia, kadar nitrat, dan kadar pospat. Data dianalisis mengunakan analysis of variance (ANOVA, α =5%) dengan program SPSS 16. jika nilai sig.<0,05 maka dikatakan perlakuan berpengaruh terhadap variabel penelitian sehingga dapat dilajutkan dengan menggunakan uji Tukey (α =5%). Hasil penelitian mendapatkan jenis substrat berpengaruh nyata terhadap variabel bobot mutlak, SGR, dan panjang mutlak stolon, dimana perlakuan tanpa substrat pasir (A, B dan C) menunjukkan pertumbuhan positif sedangkan perlakuan dengan substrat pasir (D dan E) menghasilkan pertumbuhan negatif pada variabel bobot mutlak dan SGR. Lebar frond, panjang fronds, dan jumlah rizoid tidak dipengaruhi oleh perlakuan substrat yang berbeda. Berdasarkan hasil penelitian disimpulkan bahwa penggunaan substrat lumpur dan pecahan batu karang menghasilkan pertumbuhan terbaik dalam bentuk bobot mutlak dan SGR, namun tidak berbeda nyata dengan substrat lumpur 100% atau lumpur dicampur pecahan cangkang tiram. Penggunaan substrat berupa pasir kurang direkomendasikan digunakan di tambak pasang surut sebab memberikan bobot mutlak dan SGR negatif, serta panjang stolon dan morfometrik fronds lebih kecil daripada substrat tanpa komponen pasir.
Potensi Mangrove (Rhizophora mucronate) Sebagai Tisane yang Kaya Fenol Dan Antioksidan
Authors: Hardiningtyas Safrina Dyah , Purwaningsih Sri , Alam M. Sastra , Sinulingga Fahri 
Published: January 2025

Rhizophora mucronata (R. mucronata) merupakan jenis mangrove yang banyak dijumpai di Indonesia. Daun, buah dan bunga R. mucronata diketahui mengandung komponen bioaktif sehingga dapat dimanfaatkan untuk pembuatan tisane atau teh herbal. Kandungan fenol dan aktivitas antioksidan tisane dari beberapa bagian R. muconata masih belum diketahui. Penelitian ini bertujuan menentukan komponen kimiawi serta aktivitas antioksidan yang terkandung dalam tisane daun, bunga dan buah R. mucronata. Rancangan yang digunakan pada penelitian ini yaitu rancangan acak lengkap (RAL) dengan perlakuan perbedaan bagian meliputi daun, bunga dan buah dengan tiga kali ulangan. Metode penelitian meliputi karakterisasi komponen kimiawi daun, bunga dan buah, antara lain proksimat, logam berat, dan fitokimia; ekstraksi komponen bioaktif, serta analisis total fenol dan aktivitas antioksidan ekstrak R. mucronata. Ketiga bagian tanaman R. mucronata dikeringkan dengan menggunakan dehydrator suhu 50 ºC, kemudian diekstraksi dengan maserasi menggunakan air panas suhu ±100 ºC selama 1 jam untuk memperoleh bioaktif. Hasil penelitian menunjukkan bahwa daun, bunga dan buah R. mucronata memiliki kandungan logam berat dibawah standar SNI teh kering dalam kemasan dan aman untuk dikonsumsi. Ekstrak bunga memiliki aktivitas antioksidan tertinggi 55,21±5,156 mg asam askorbat/g ekstrak dan total fenol tertinggi 2,44±0,354 mg/g. Terdapat korelasi positif antara aktivitas antioksidan dan total fenol. Kandungan senyawa bioaktif pada ekstrak bunga yaitu fenol, saponin, flavonoid, tanin dan triterpenoid.