bluuebunny/crossref_metadata_2025_split huggingface dataset:
Potential injectable hydrogels as biomaterials for central nervous system injury: A narrative review
Authors: Sarma Santa , Deka Dhruva J. , Rajak Prakash , Laloo Damiki , Das Trishna , Chetia Purbajit , Saha Dipankar , Bharali Alakesh , Deka Bhargab 
Published: November 2023

AbstractNumerous modalities exist through which the central nervous system (CNS) may sustain injury or impairment, encompassing traumatic incidents, stroke occurrences, and neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease. Presently available pharmacological and therapeutic interventions are incapable of restoring or regenerating damaged CNS tissue, leading to substantial unmet clinical needs among patients with CNS ailments or injuries. To address and facilitate the recovery of the impaired CNS, cell‐based repair strategies encompass multiple mechanisms, such as neuronal replacement, therapeutic factor secretion, and the promotion of host brain plasticity. Despite the progression of cell‐based CNS reparation as a therapeutic strategy throughout the years, substantial barriers have impeded its widespread implementation in clinical settings. The integration of cell technologies with advancements in regenerative medicine utilizing biomaterials and tissue engineering has recently facilitated the surmounting of several of these impediments. This comprehensive review presents an overview of distinct CNS conditions necessitating cell reparation, in addition to exploring potential biomaterial methodologies that enhance the efficacy of treating brain injuries.
An empirical snapshot of English corporate insolvencies
Authors: Khan Asad 
Published: November 2023

AbstractThe article presents an empirical study of English corporate insolvencies initiated between December 2016 and December 2018. The research focuses on creditors' voluntary liquidations (‘CVLs’), the most frequently occurring insolvency procedure. It also looks at a few administrations and compares findings with CVLs to analyse which procedure may lead to better returns to creditors. The article highlights key statistics such as the average costs of procedures and the impact of the prescribed part fund on distribution. Further, the study assesses HMRC's potential debt recovery following its return as a preferential creditor and discusses whether Crown preference is justified. Given that data analysis on the practicalities of distribution during insolvency is lacking, the empirical study arguably helps fill a gap in the literature. Essentially, the article provides quantitative data on the practicalities of distribution and assesses the impact of the order of priority on repayment to creditors.
Use of photobiomodulation (880 nm) for anesthesia puncture pain reduction: A split‐mouth case report
Authors: Ferreira Giovanna Fontgalland , Machado Glaucia Gonçales Abud , Roncolato Vinicius Leão , Bussadori Sandra Kalil , Motta Lara Jansiski , Duran Cinthya Cosme Gutierrez , Fernandes Kristianne Porta Santos , Mesquita‐Ferrari Raquel Agnelli , Horliana Anna Carolina Ratto Tempestini 
Published: November 2023

AbstractThe objective of this split‐mouth case report is to evaluate the effect of photobiomodulation (PBM, 880 nm) on pain control during pterygomandibular puncture. A patient received anesthesia on both sides of the mouth in a randomized manner. On the right side, an 880‐nm infrared laser was applied immediately before local anesthesia. On the left side, a sham laser was applied using the same technique. There was a 50% reduction in pain levels on the PBM‐treated side compared to the PBM‐sham side, as measured by the visual analog scale. Sensitivity tests revealed that anesthesia was more effective on the PBM side. There was no difference in blood pressure. This case report suggests that PBM (880 nm) before anesthesia may alleviate puncture pain associated with pterygomandibular anesthesia. Although these findings are based on a single case report, they can serve as the initial stepping stone for further randomized clinical trials.
Hip joint contact forces are lower in people with femoroacetabular impingement syndrome during squat tasks
Authors: Perrone Mattia , Guidetti Martina , Galli Manuela , Nho Shane J. , Wimmer Markus A. , Malloy Philip 
Published: November 2023

AbstractIt remains unknown if hip joint forces during squat tasks are altered in people with femoroacetabular impingement syndrome (FAIS). The aim of this study is to compare hip joint forces between people with FAIS and healthy controls during double leg squat and single leg squat tasks and within limbs during a single leg squat task in people with FAIS. Kinematic and kinetic data were collected in eight people with FAIS and eight healthy matched controls using 3D motion capture and force plates. AnyBody Modeling System was used to perform musculoskeletal simulations to estimate hip joint angles, forces, and moments for all participants. Estimates were postprocessed with AnyPyTools and converted into normalized time series to be compared using a 1D statistical nonparametric mapping (SnPM) approach. SnPM with an independent samples t‐test model was used to compare people with FAIS to controls, while a paired samples model was used to compare involved to uninvolved limb in people with FAIS. Patients demonstrated lower proximodistal force compared to controls (p < 0.01) and compared to the uninvolved side (p = 0.01) for single leg squat. The smaller joint contact forces in people with FAIS compared to controls could represent a strategy of reduced muscle forces to avoid pain and symptoms during this high demand task. These findings when combined with imaging data could help assess the severity of FAIS on hip related function during higher demand tasks.
Tumor‐infiltrating lymphocytes in patients undergoing esophagectomy following neoadjuvant DCF therapy
Authors: Takahashi Keita , Sakashita Yuki , Murahashi Mutsunori , Kubota Hoshiho , Shimoda Masayuki , Ishikawa Yoshitaka , Tanishima Yuichiro , Kurogochi Takanori , Yano Fumiaki , Eto Ken 
Published: November 2023

AbstractBackgroundAccumulating evidence suggests that expression levels of tumor‐infiltrating (TI) cells may play a prognostic role in patients with esophageal cancer who have undergone esophagectomy. However, its effect on patients undergoing neoadjuvant docetaxel, cisplatin, and 5‐fluorouracil (DCF) therapy followed by esophagectomy for esophageal squamous cell carcinoma (ESCC) remains unclear. Therefore, this study aimed to elucidate the prognostic impact of TI cells in patients who underwent esophagectomy following neoadjuvant DCF therapy.MethodsOverall, 81 patients with ESCC who underwent curative esophagectomy following neoadjuvant DCF therapy were included. The number of TI CD8+ cells was determined using light microscopy at ×400 in tumor invasive margins. Receiver operative characteristic curve was used to determine the cutoff values for mortality for continuous variables; the patients were separated into high and low TI CD8+ cell groups and their backgrounds and clinical outcomes were compared.ResultsOverall and relapse‐free survival were significantly worse in the TI CD8+‐low group than that in the TI CD8+‐high group (p < 0.01). Multivariate analysis revealed that positive ypN (hazard ratio [HR], 3.12; 95% confidence interval [CI], 1.08–9.02) and low TI CD8+ cell levels (HR, 2.77; 95% CI, 1.31–5.85) were independent prognostic factors for overall survival. Furthermore, positive venous invasion (HR, 2.63; 95% CI, 1.29–5.35) and low TI CD8+ cell levels (HR, 2.77; 95% CI, 1.70–5.46) were significant prognostic factors for relapse‐free survival.ConclusionsLow TI CD8+ cell level was a prominent prognostic factor for patients with ESCC undergoing neoadjuvant DCF therapy followed by esophagectomy.
Dimethylmercury in natural waters—analytical and experimental considerations
Authors: West Johannes , Babi Diana , Azaroff Alyssa , Jonsson Sofi 
Published: November 2023

AbstractMono‐ and dimethylmercury (MMHg and DMHg, respectively) are the two primary organic forms of mercury (Hg) found in natural waters. While experimental approaches to characterize the environmental behavior of MMHg and inorganic forms of Hg are widely used today, few laboratories conduct experimental studies entailing the use of DMHg. In this paper, we have evaluated and developed different analytical and experimental approaches to quantify and use DMHg in laboratory studies. We demonstrate that DMHg can be analyzed from samples where MMHg is derivatized using sodium tetraethyl borate and where the matrix effects of dissolved sulfide are masked using copper sulfate. Tests, where the calibration curves of MMHg and DMHg were used, showed that MMHg may be used to calibrate for DMHg. For the pre‐concentration of DMHg, both traps filled with Tenax® TA and Bond Elut ENV were found suitable. We observed good recoveries of DMHg added to different types of natural waters or purified water containing aquarium salt, sodium chloride and dissolved sulfide, iron sulfide, and cadmium sulfide at DMHg : sulfide molar ratios > 10−6. In addition to evaluating these analytical aspects, we present suitable subsampling techniques for DMHg‐containing solutions, the recovery of DMHg when filtering DMHg through different types of filters, and experimental data on the long‐term stability of DMHg added to different types of waters and stored at different temperatures. Finally, we present and discuss a new synthetization protocol for preparing aqueous solutions containing DMHg free of organic solvents and where handling DMHg in a pure form is prevented.
Optimization of process parameters effects on mechanical properties of selective laser melted iron samples
Authors: Hemmati M. , Modabberifar M. , Taheri M. , Sajjadi M. A. 
Published: November 2023

AbstractSelective laser melting is an additive manufacturing technology whereby parts are built through selective melt of a powder bed by a laser beam. This technology is used to produce net shape parts in 3D printers. In this study, the effect of selective laser melting parameters on the mechanical properties (ultimate tensile strength and hardness) of iron has been experimentally extracted, and the optimum levels of the parameters have been determined for optimum mechanical properties using signal‐to‐noise analysis. The selected parameters include the laser power, the laser scanning speed, and the laser hatch distance, and the design of experiments was done by the Taguchi method. The main effects of factors and interactions were considered in this paper. The results show that the optimum parameter levels for the ultimate tensile strength include the laser power of 200 W, the laser scanning speed of 600 mm/s, and the hatch distance of 70 μm. The optimal parameters for hardness are similar to the maximum tensile strength, except that the optimum hatch distance is 60 μm.
Peer effect, bank concentration, and crises: Evidence from the United States
Authors: Zeng Jhih‐Hong , Lin Sin‐Jin 
Published: November 2023

AbstractThis research analyzes the impact of banks' peer effect in lending on the bank concentration‐crisis nexus for the period 2015–2021 in the United States. The analysis finds that a high level of bank concentration increases a crisis via the channel of banks' peer effect in lending, to which the imitative behavior of big banks is deemed to be the cause of deteriorating the damage of bank concentration on the stability of the banking sector. The results propose policy implications and what banks should do when treating financial market sustainability as their duty on the environmental, social, and governance (ESG) issues.
Very long‐term follow‐up of Indiana Pouches proves durability
Authors: Polm Pepijn D. , Wyndaele Michel I. A. , de Kort Laetitia M. O. 
Published: November 2023

AbstractIntroductionAn Indiana Pouch (IP) is a heterotopic, continent, urinary diversion from an ileocolonic segment. Numerous studies have investigated its long‐term outcomes, albeit none extending beyond a 5‐year follow‐up period. IPs can be used as urinary diversion for benign indications and as such are constructed in typically young patients. As a consequence of their extended lifespan, there is a need for very long‐term (>5 years) IP outcome data and comprehensive complication analysis.Materials and MethodsIn this retrospective cohort study, the data of all patients attending our academic functional urology tertiary referral center for surveillance between 2015 and 2022 after an earlier IP procedure without uro‐oncological indication were analyzed. The primary objective was to identify the prevalence of complications associated with IP, including stomal stenosis, ureter‐pouch stenosis, pouch calculi, stomal leakage, pouch perforation, and parastomal herniation, and to determine the time span between creation of the IP and occurrence of complications.ResultsA cohort of 33 patients (23 female) was analyzed. Median age at IP creation was 38 (range 5–62) years. Median follow‐up was 258 (range 24–452) months. During follow‐up, 22 (67%) patients underwent at least one surgical revision. In total, 45 revision procedures were performed. The estimated mean revision‐free survival was 198 (95%‐CI 144–242) months.ConclusionTwo‐thirds of our IP patients required surgical revision during very long‐term follow‐up. However, the mean revision‐free survival was 198 months. This establishes the IP as a durable and resilient option for urinary diversion, yet underlines the need for lifelong follow‐up as some of these complications and indication were subclinical. These results contribute significantly to patient counseling when discussing different options for urinary diversion, especially at a younger age.
Water Futures in Australia: Materialities, Temporalities, Imaginaries
Authors: Babidge Sally , Eickelkamp Ute , Connor Linda 
Published: November 2023

ABSTRACTThis special issue is part of a shift in social science and humanities thinking and in public awareness towards planetary water concerns. As societal and scholarly attention to the wet element – and its political import and its cultural constitution – is growing, we ask, how can we rethink our relationships with water in Australia now and into the future? The collection of papers in this issue shows that water responds to human practices which in turn are grounded in cultural imaginaries. Water is thus real in diverse ways, and makes possible diverse material, political and cultural relationships. Taking our lead from the ideas that contributors have developed from this and other questions posed for the issue, our introductory discussion considers three themes that are key to the understanding of water futures in Australia: materialities, temporalities and imaginaries.
Land market misallocation, regional integration, and economic growth: Evidence from the Yangtze River Delta Region, China
Authors: Zhong Xiaoping , Zhou Shaojie , Yu Xiaohua 
Published: November 2023

AbstractIntensive land use and land marketization is an important engine for promoting regional integration, especially on the background of China's fragmented land market. It might be difficult to establish an integrated national land market in the short run. As a compromise, the establishment of regional land markets consisting of a few neighboring provinces could be an option. Particularly, the Yangtze River Delta Region (YRDR), could be an ideal place for such a policy trial. This study uses the data of Shanghai, Jiangsu, Zhejiang, and Anhui in YRDR from 1999 to 2017 to quantitatively calibrate possible economic benefits when the land misallocation is corrected with an integrated land market. We find that, if an integrated construction land market was established in YRDR, and Anhui could transfer some of its construction land quota to Shanghai, the transaction between Anhui and Shanghai in 2017 could bring an improved income of 289.8 billion yuan in YRDR, ceteris paribus, about 1.73% of the regional gross domestic product. The integration of regional land markets has brought about significant efficiency improvements. This study provides insights into sustainable economic growth in future China and the regional development strategy of other developing countries.
Probing conformational properties of conjugated polymers in dilute solutions under variable solvent quality via coarse‐grained modeling
Authors: Li Zhaofan , Wang Yang , Ma Guorong , Liao Yangchao , Gu Xiaodan , Xia Wenjie 
Published: November 2023

AbstractConjugated polymers (CPs), characterized by rigid conjugation backbones and flexible peripheral side chains, hold significant promise in various organic optoelectronic applications. In this study, we employ coarse‐grained molecular dynamics (CG‐MD) simulations to investigate the intricate interplay of solvent quality, temperature, and chain architecture (e.g., side‐chain length and molecular mass) on the conformational behaviors of CPs in dilute solutions. Our research uncovers distinctive conformational behaviors under varying solvent conditions, highlighting the versatile nature of polymer chains, which can adopt extended configurations in good solvents and transition to aggregated states in poor solvents. Additionally, the mass scaling exponent , a robust structural descriptor, consistently described CPs behavior across diverse architectures and solvent conditions. Furthermore, our study shows that a CP with longer side‐chain exhibits improved solubility, which is further confirmed by experimental observations. Moreover, our analysis of the shape descriptor provided valuable insights into the symmetry and dimensionality of CPs under varying solvent conditions. These findings offer a comprehensive understanding of conformational behaviors of CPs in dilute solution, which are helpful in guiding the conformational design of polymer for specific applications.
An unusual cause of progressive dyspnoea, pulmonary nodules and pleural effusions
Authors: Venkatesan Sudharsan , Ramnani Bharti , Klebe Sonja , Mo Lin 
Published: November 2023

AbstractEosinophilic granulomatosis with polyangiitis (EGPA) is part of the ANCA‐associated vasculitides, although ANCA‐negative presentations are not infrequent. Asthma, allergic rhinitis and peripheral eosinophilia are classic associations although pleural effusions are an uncommon manifestation of EGPA. We describe a 35‐year old Caucasian adult with asthma who presented with progressive dyspnoea, cough, peripheral eosinophilia and imaging that showed pulmonary nodules with pleural effusions. Biopsy with histopathological review confirmed the diagnosis of EGPA with steroid therapy resulting in significant resolution of symptoms and imaging findings.
Active set prediction for nonlinear model predictive control on a shrinking horizon based on the principle of optimality
Authors: Dyrska Raphael , Mönnigmann Martin 
Published: November 2023

SummaryWe provide insights into the structure of the set of active constraints arising for optimal solutions to nonlinear model predictive control problems along a shrinking horizon. The principle of optimality combined with a particular order of the constraints allows the prediction of the future active sets without solving the corresponding optimization problem. By describing the development of optimal active sets along a shrinking horizon, we state an important relationship for transferring ideas such as dynamic programming approaches from the linear to the nonlinear case. We further use the information about active and inactive constraints to rearrange and remove constraints of the original nonlinear program as described in previous work and thus simplify the problem. Numerical experiments show for the problem class treated here that the inherent robustness coming with the regional characteristic of the active sets with respect to the state space makes this approach useful also if uncertainties are present.
A Versatile Shaping Method of Very‐High Loading Porous Solids Paper Adsorbent Composites
Authors: Tignol Pierre , Pimenta Vanessa , Dupont Anne‐Laurence , Carvalho Silvia , Mohtar Abeer Al , Inês Severino Maria , Nouar Farid , Pinto Moisés L. , Serre Christian , Lavédrine Bertrand 
Published: November 2023

AbstractOwing to their high porosity and tunability, porous solids such as metal–organic frameworks (MOFs), zeolites, or activated carbons (ACs) are of great interest in the fields of air purification, gas separation, and catalysis, among others. Nonetheless, these materials are usually synthetized as powders and need to be shaped in a more practical way that does not modify their intrinsic property (i.e., porosity). Elaborating porous, freestanding and flexible sheets is a relevant shaping strategy. However, when high loadings (>70 wt.%) are achieved the mechanical properties are challenged. A new straightforward and green method involving the combination softwood bleached kraft pulp fibers (S) and nano‐fibrillated cellulose (NFC) is reported, where S provides flexibility while NFC acts as a micro‐structuring and mechanical reinforcement agent to form high loadings porous solids paper sheets (>70 wt.%). The composite has unobstructed porosity and good mechanical strength. The sheets prepared with various fillers (MOFs, ACs, and zeolites) can be rolled, handled, and adapted to different uses, such as air purification. As an example of potential application, a MOF paper composite has been considered for the capture of polar volatile organic compounds exhibiting better performance than beads and granules.
Proof of Necessary Work: Succinct State Verification with Fairness Guarantees
Authors: Kattis Assimakis , Bonneau Joseph 
Published: November 2023

AbstractBlockchain-based payment systems utilize an append-only log of transactions whose correctness can be verified by any observer. Classically, verification costs grow linearly in either the number of transactions or blocks in the blockchain (often both). Incrementally Verifiable Computation (IVC) can be used to enable constant-time verification, but generating the necessary proofs is expensive. We introduce the notion of Proof of Necessary Work (PoNW), in which proof generation is an integral part of the proof-of-work used in Nakamoto consensus, producing proofs using energy that would otherwise be wasted. We implement and benchmark a prototype of our system, enabling stateless clients to verify the entire blockchain history in about 40 milliseconds.
SymTFTs and duality defects from 6d SCFTs on 4-manifolds
Authors: Chen Jin , Cui Wei , Haghighat Babak , Wang Yi-Nan 
Published: November 2023

Abstract
In this work we study particular TQFTs in three dimensions, known as Symmetry Topological Field Theories (or SymTFTs), to identify line defects of two-dimensional CFTs arising from the compactification of 6d (2, 0) SCFTs on 4-manifolds M4. The mapping class group of M4 and the automorphism group of the SymTFT switch between different absolute 2d theories or global variants. Using the combined symmetries, we realize the topological defects in these global variants. Our main example is ℙ1 × ℙ1. For N M5-branes the corresponding 2d theory inherits ℤN 0-form symmetries from the SymTFT. We reproduce the orbifold groupoid for theories with ℤN 0-form symmetries and realize the duality defects at fixed points of the coupling constant under elements of the mapping class group. We also study other Hirzebruch surfaces, del Pezzo surfaces, as well as the connected sum of ℙ1 × ℙ1. We find a rich network of global variants connected via automorphisms and realize more interesting topological defects. Finally, we derive the SymTFT on more general 4-manifolds and provide two examples.