bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of a mutation in the <i>RUNX1</i> gene with the outcome of the disease in acute myeloid leukemia (meta-analysis)
Authors: Nikonorova M. L. , Kats L. K. 
Published: December 2023

The article summarizes the data of a systematic review of scientific publications on acute myeloid leukemia over the past 10 years.The objective was to conduct a meta-analysis of the data published in the open press to investigate the nature of the association of mutations in the RUNX1 gene with the outcome of acute myeloid leukemia.Methods and materials. The search for publications was carried on library platforms eLibrary.ru, Google Academy, PubMed, Web of Science according to the criteria PRISMA 2020. The selection of studies was carried out using the Rayyan online program. The meta-analysis was performed on the basis of the RStudio application package. The main characteristics in the studies were reflected in overall survival, relapse-free survival, hazard ratio and were assessed by a standardized effect size. The magnitude of the effect was based on the difference between the observed patients and patients with mutations in the RUNX1 gene. The outliers filtering based on the combines confidence interval. The bias of publications was assessed visually and quantitatively.Results. The search identified 579 publications, 10 were included in the meta-analysis, the total sample was 2733 patients. The results of statistical tests on the Cochran Q-test (p-value < 0.0001) and the Higgens–Thompson test (92 %) indicate a high heterogeneity of the included publications. The variance of heterogeneity together with the 95 %CI (0.177; 1.528) indicates the heterogeneity of the research results. The combined 95 %CI (0.47; 2.90) does not suggest that mutations in the RUNX1 gene always lead to a poor prognosis. Egger’s regression test (p-value > 0.098) showed no publication bias.Conclusion. The results of the study revealed a statistical relationships between the influence of mutations in the RUNX1 gene and the outcome of the disease.
Warming-up for the Latest on Diagnosing and Managing Tendinopathy
Authors: Rio Ebonie K. , Murphy Myles C. 
Published: December 2023

SYNOPSIS: JOSPT is starting 2024 on a high, with a tendinopathy-focused edition that showcases more of the high-quality tendinopathy research you know and love in systematic reviews, original research articles, a consensus paper, and editorials. As any athlete knows, a good warm-up is crucial to performing well at the main event. Here, we help you warm up and prime your brain to take on all the content of this tendinopathy-focused issue of the Journal. J Orthop Sports Phys Ther 2024;54(1):1-2. Epub 5 December 2023. doi:10.2519/jospt.2023.12440
MODELS OF ALANE DECOMPOSITION UNDER DYNAMIC HEATING
Authors: Жукова М.М. , Столяров П.Н. , Мисюрин Ю.А. , Алфимов В.Н. , Базуров И.А. , Костерова А.А. 
Published: December 2023

Исследование твердофазных процессов в условиях динамического нагрева образца представляет значительный интерес в связи с возможным изменением кинетической модели, по сравнению с разложением в условиях постоянной температуры. Для обработки экспериментальных данных твердофазных процессов используют как модели одностадийных реакций, таких как модели Киссинджера, Фридмана, Озава-Флина, Аврами-Ерофеева и ряд других, а также модели многостадийных реакций. Для многостадийных моделей для каждой стадии используются уравнения типа Аврами- Ерофеева. Кроме простых моделей используется изоконверсионный метод, позиционируемый как универсальный метод, не требующий предположения о лимитирующих стадиях процесса. Экспериментальные данные процесса разложения алана в условиях отсутствия кислорода удовлетворительно описываются либо уравнением автокатализа первого порядка (по потере массы), либо двухстадийной кинетикой (данные ДСК или волюмометрия). Разложение в присутствии кислорода требует более сложной модели (трехстадийной) с учетом появления окисной пленки на поверхности алана.
The study of solid-phase processes under conditions of dynamic heating of a sample is of considerable interest. Will there be a change in the kinetic model, that is, limiting processes, in comparison with decomposition under conditions of constant temperature? To what extent will the kinetic parameters of the processes change? For processing experimental data of solid-state processes, both models of single-stage reactions are used, such as the models of Kissinger, Friedman, Ozawa-Flyn, Avrami-Erofeev and a number of others, as well as models of multi-stage reactions. For multi-stage models, Avrami-Erofeev-type equations are used for each stage. In addition to simple models, the isoconversion method is used, which is positioned as a universal method that does not require assumptions about the limiting stages of the process. Experimental data on the decomposition of alane in the absence of oxygen are satisfactorily described either by the first-order autocatalysis equation (in terms of mass loss) or by two-stage kinetics (DSC data or volumetrics). Decomposition in the presence of oxygen requires a more complex model (three-stage) taking into account the appearance of an oxide film.
METHOD OF SYNTHESIS OF STABILITY INDICATORS OF THE FUNCTIONING OF FIELD MAIN PIPELINES WHEN THE LINEAR PART IS DAMAGED
Authors: Елькин А.В. , Середа В.В. , Савин И.И. 
Published: December 2023

В статье описываются метод синтеза показателей устойчивого функционирования полевых магистральных трубопроводов при поражении линейной части. Метод основан на обработке большого объема статистических данных, полученных Вооруженными силами СССР в ходе эксплуатации полевых магистральных трубопроводов в условиях боевых действий в Афганистане в 1981-1989 годах и выборе статистического распределения, наилучшим образом описывающего накопленные статистические данные.
The article describes a method for synthesizing indicators of the stable functioning of field trunk pipelines in case of damage to the linear part. The method is based on the processing of a large volume of statistical data obtained by the Armed Forces of the USSR during the operation of field trunk pipelines in the conditions of hostilities in Afghanistan in 1981-1989 and the choice of a statistical distribution that best describes the accumulated statistical data.
Portable ballistic stand with multi-angle X-ray and optical registration
Authors: Долгих А.В. , Пальчиков Е.И. , Параскун А.Г. , Самойленко М.С. 
Published: December 2023

В работе рассматривается модель баллистического стенда с многоракурсной импульсной рентгеновской и скоростной оптической регистрацией, разработанного для ударных испытаний образцов углеволоконных и стекловолоконных композитных материалов на ударное воздействие града и мусора со скоростями до 1 км/с. Разработанный стенд также может быть применим для исследования с помощью импульсных рентгеновских методик динамики ранений и динамики защиты от пуль стрелкового оружия. Рассматривается как модель стенда, так и система оптической и рентгеновской регистрации исследуемых процессов, система синхронизации, подсветки.The paper considers a model of a ballistic stand with multi-angle X-ray and optical registration, designed for impact testing of samples of carbon fiber and fiberglass composite materials for the impact of hail and debris at speeds up to 1 km/s. The developed stand can also be used to study the dynamics of wounds and the dynamics of terminal ballistics by means of pulse X-ray techniques. The model of the stand is considered, as well as the system of optical and X-ray registration of the studied processes, synchronization system, illumination.
Optimization of Tuff Stones Content in Lightweight Concrete Using Artificial Neural Networks
Authors: Yasin Amjad A. , Awwad Mohammad T. , Malkawi Ahmad B. , Maraqa Faroq R. , Alomari Jamal A. 
Published: December 2023

Tuff stones are volcanic sedimentary rocks formed by the consolidation of volcanic ash. They possess unique geological properties that make them attractive for a variety of construction and architectural applications. Considerable amounts and various types of Tuff stones exist in the eastern part of Jordan. However, the use of Tuff stones often requires experimental investigations that can significantly impact the accuracy of their physical and mechanical characteristics. To ensure consistent and predictable properties in their mix design, it is essential to minimize the effects of these experimental procedures. Artificial neural networks (ANNs) have emerged as a promising tool to address such challenges, leveraging their ability to analyze complex data and optimize concrete mix design. In this research, ANNs have been used to predict the optimum content of Tuff fine aggregate to produce structural lightweight concrete with a wide range (20 to 50 MPa) of compressive strength. Three different types of Tuff aggregates, namely gray, brown, and yellow Tuff, were experimentally investigated. A set of 68 mixes was produced by varying the fine-tuff aggregate content from 0 to 50%. Concrete cubes were cast and tested for their compressive strength. These samples were then used to form the input dataset and targets for ANN. ANN was created by incorporating the recent advancements in deep learning algorithms, and then it was trained, validated using data collected from the literature, and tested. Both experimental and ANN results showed that the optimum content of the various types of used Tuff fine aggregate ranges between 20 to 25%. The results revealed that there is a clear agreement between the predicted values using ANN and the experimental ones. The use of ANNs may help to cut costs, save time, and expand the applications of Tuff aggregate in lightweight concrete production. Doi: 10.28991/CEJ-2023-09-11-013 Full Text: PDF
Solving Innovative Problems of Thrust Vector Control Based on Euler's Scientific Legacy
Authors: Sazonov Yuri A. , Mokhov Mikhail A. , Gryaznova Inna V. , Voronova Victoria V. , Tumanyan Khoren A. , Konyushkov Egor I. 
Published: December 2023

This study aims to develop an interdisciplinary approach to solving innovative thrust vector control problems. The methodology involves the development of a working hypothesis about the ejection process when using a controlled nozzle to deflect the thrust vector (velocity vector) in any direction within a complete geometric sphere. When developing the working hypothesis, a multilateral analysis of individual facts and scientific and technical information is performed using tools in the "big data" area, assessing opportunities to apply the "Foresight" methodology for predicting the development of fluidics. The authors propose new mathematical models to describe the thrust vector in the distribution of the mass flow rate of the fluid medium between flow channels. Patents for inventions support the novelty of scientific results that reveal new opportunities for more active development of fluidics as applied to simple and complex jet systems with low and extremely high energy density in flows. The proposed methodology rests on a modern computer base and is a logical continuation and development of well-known Euler’s works. The computer simulation of multiflow jet devices mainly focuses on power engineering, production, and processing of hydrocarbons. Some results of this research work, including patented design developments and calculation methods, also apply to developing robotics, unmanned vehicles, and programable jet systems. The authors attribute further development of the interdisciplinary approach for solving inventive problems to the use of different AI options. Doi: 10.28991/CEJ-2023-09-11-017 Full Text: PDF
A Comparative Study on the Optimal Modeling of Laminated Glass
Authors: Hejazi Moheldeen A. , Sari Ali 
Published: December 2023

This study addresses the challenging task of modeling laminated glass responses to extreme loading scenarios for the design and analysis of protective structures. The primary objective is to seek an optimal modeling approach that balances accuracy and computational efficiency. To achieve this, the failure modeling of laminated glass layups comprising thin and thick panels with three and eleven layers is investigated under blast loading conditions. Various simulation techniques are employed, including the finite element method (FEM) with element erosion/deletion, smoothed particle hydrodynamics (SPH), and a hybrid approach involving the conversion of elements into particles. The feasibility and limitations of each technique are examined, considering both accuracy and computational cost. Experimental results from arena and shock tube testing scenarios assess the deployed modeling techniques and the presented comparisons. Emphasis is placed on mesh sensitivity and the significance of adaptive meshing in capturing fracture patterns. The present paper suggests that utilizing hybrid techniques results in optimal modeling outcomes. Furthermore, the stability of the modeling results under diverse blast conditions is confirmed. This article contributes to the field by offering insights into modeling laminated glass responses to extreme loading, emphasizing the use of hybrid techniques to strike a balance between accuracy and computational efficiency. This research enhances the understanding of protective structure design and analysis, highlighting the critical importance of computational methods in this context. Doi: 10.28991/CEJ-2023-09-11-018 Full Text: PDF
An Evaluative Review of Recycled Waste Material Utilization in High-Performance Concrete
Authors: D. A. Jasim Al Mashhadani , Wong Leong  Sing , Kong Sih Ying , W. Al-Zand Ahmed , Midhin Midhin A. K. 
Published: December 2023

The disposal of waste materials and their adverse effects on the environment have become a worldwide concern, disturbing the fragile ecological equilibrium. With growing awareness of sustainability in the construction industry, it is of great importance to recycle waste materials for producing high-performance concrete (HPC). This aligns with the twelfth Sustainable Development Goal (SDG) of the United Nations, emphasizing responsible production and consumption, especially concerning the production of HPC using waste materials and energy-efficient methods. The review evaluates the purposeful utilization of recycled waste materials to improve the engineering characteristics of HPC, taking into consideration pertinent literature. It encompasses a comparative evaluation of strength development, water absorption, microstructures, and x-ray diffraction (XRD) analyses of HPC manufactured with different types of recycled waste materials. The key result of the review showed that using incinerated bottom ash (IBA) below 25% and incorporating 40% copper slag can enhance HPC’s mechanical performance. Additionally, recycled coarse aggregate (RCA) can replace up to 50% of conventional aggregate in self-compacting HPC with minimal impact on durability properties. In HPC cement substitution research, fly ash, silica fume, and metakaolin are prominent due to their availability, with fly ash showing remarkable durability when used as a 15% cement replacement. This thorough review offers valuable insights for optimizing the utilization of recycled waste materials in the development of environmentally friendly HPC. Doi: 10.28991/CEJ-2023-09-11-020 Full Text: PDF
Torsion Improvement of Reinforced Self-Compacting Concrete Beams Using Epoxy Injection and CFRP
Authors: Elsheikh Asser , Albo-Hassan Ali S. , Al-Zayadi Sora K. 
Published: December 2023

Few researchers have investigated the internal torsional reinforcement of box timbers, so little research has been conducted on this particular fortification method. The primary objective is to find out the possibility of adding a certain percentage of RCA to the NC mixtures, as well as verifying the success achieved in repairing the cracks that occurred as a result of torsion with CFRP or injecting with epoxy, which has not been addressed in previous research and literature reviews. This study reinforces reinforced SCC box columns subjected to complete torsion with CFRP sheets and epoxy resin injections. Four reinforced SCC specimens (the first beam with 0%, the second beam with 33.3%, the third beam with 67.7%, and the fourth beam with 100% RCA by weight) were subjected to pure torsion until failure. The dimensions and reinforcement of every specimen are identical. In addition, the applied torque-twist angle relationship at the midspan and end span was investigated. Bending experiments were performed to establish load-deflection curves and assess failure modes. After structural rehabilitation, all beams exhibited increased rigidity values, according to the results. Epoxy resin and CFRP sheet contributed to the specimens' increased ultimate load. The ultimate strength of RCA beams strengthened with CFRP and injected with epoxy increased. The specimens' flexural strength was considerably enhanced by the combination of surface roughness and fracture injection, and the effectiveness of using RCA was very good; it could be replaced with NCA in concrete mixtures, according to the ratio and need. Doi: 10.28991/CEJ-2023-09-11-05 Full Text: PDF
Seepage Analysis and Optimization of Reservoir Earthen Embankment with Double Textured HDPE Geo-Membrane Barrier
Authors: Onyelowe Kennedy C. , Nimbalkar Akash , Reddy Narala G. , Baldovino Jair de Jesus A. , Hanandeh Shadi , Ebid Ahmed M. 
Published: December 2023

This research paper focuses on conducting a steady state seepage analysis along with the downstream slope factor of safety using the Modified Bishops method in a poorly compacted earthen embankment and optimizing the same reservoir earthen embankment in a case study located near Sadiyavav village in Junagadh district in Gujarat, India. The study site, situated at 21°32'06.5"N and 70°37'26.7"E, is renowned for its Asiatic lions. The analysis and optimization were performed with a double-textured High-Density Polyethylene (HDPE) Geo-membrane barrier. Previously, designs and numerical solutions proposed homogenous embankments and too poorly compacted with no drainage arrangements, which led to anisotropic conditions within the section and water seeping out, cutting the phreatic line. The paper presents the documented improvements in the factor of safety achieved through the seepage analysis and the optimization of the HDPE Geo-membrane barrier. Two improvement techniques were studied using the “Limiting Equilibrium-Finite Element Method” (LS-FEM). The first using (HDPE) Geo-membrane stabilized with gabions, and the second alternative using HDPE Geo-membrane with gabions in addition to rock toe. The study results showed improvements in the downstream slope stability for the two alternatives by 3% and 10%, respectively. Doi: 10.28991/CEJ-2023-09-11-07 Full Text: PDF
El ahorro como estrategia utilizada por los jóvenes universitarios para tener un apalancamiento en sus proyectos de emprendimiento
Authors: Hernández Silva Ariadne Patricia , Vázquez-Alamilla Ismael , Bolaños Rodríguez Ernesto 
Published: December 2023

Esta investigación analiza la opción que tiene la comunidad universitaria del país, de ahorrar mientras estudian su carrera, usando estos recursos económicos como apalancamiento de sus proyectos de emprendimiento al final de su carrea profesional, aplicable a cualquier área del conocimiento, lo cual ayudaría a la creación de empresas y su sobrevivencia, así como al crecimiento económico local, a la generación de empleos y mayor productividad del país. La investigación es predominantemente teórica, elaborada por medio de una revisión bibliográfica que tiene como finalidad indagar sobre los ingresos que tienen los estudiantes, así como las fuentes del mismo; también permite conocer en qué gastan dichos recursos; su conducta de ahorro y las principales fuentes de financiamiento para los emprendedores, las cuales muchas veces son las causantes de que las empresas queden fuera del mercado comercial en etapas iniciales, evitando que puedan crecer y llegar a consolidarse en el mercado.
Evolución de la participación política de las mujeres: Un compromiso histórico - social colectivo
Authors: Valerio Nolasco Mayra Anaid , Coronado Meneses Myriam 
Published: December 2023

las mujeres pretenden dejar las esferas privadas y pasar a lo público, siendo juzgadas socialmente por no cumplir con los roles y estereotipos sociales de cada una de las épocas, se debe mencionar que este no es un problema nuevo, sino más bien, es una lucha que ha dado frutos de manera progresiva durante el pasar de los años y como resultados de las disputas de las feministas de la época. Se pretende con este escrito visibilizar a aquellas mujeres tenaces que lucharon valientemente en la obtención de los derechos político electorales y aportar una reflexión de la evolución en la participación política de las mujeres.
Present and yet absent, bodied and yet bodiless: the paradoxical dyads of "Bramshill, being the Memoirs of Joan Penelope Cope" (1938)
Authors: Johnson Daisy 
Published: December 2023

In 1937, triggered by the imminent sale of her ancestral home Bramshill, Joan Penelope Cope wrote and illustrated her memoirs: "Bramshill, being the Memoirs of Joan Elizabeth Cope". She was twelve years old at time of writing, thirteen upon publication, and her book was “never intended for publication”. It was, nevertheless, published to vocal acclaim both nationally and internationally with critics lauding Cope's achievement both on a literary and artistic level. Yet as much as these readings celebrated Cope, they also worked to remove her from her own text due to a preoccupation with Bramshill and its cultural legacy. In this piece I examine the impact of that preoccupation and recognise how Cope herself often contributed towards it through her own anticipatory aesthetic. I conclude that the often paradoxical demands placed upon both author and text result in Cope being read as something of a 'ghost', both present and absent, bodied and yet bodiless, within her own work.
Educação física em discussão - Volume 4
Authors: Soares Fernanda Lima , Alvares Poliane Dutra , Santana Paulo Vitor Albuquerque , Silva Alanna Joselle Santiago , da Silva Dias Karoline 
Published: December 2023

Este livro trata-se de uma obra pioneira no estado do Maranhão, tendo como principais protagonistas os alunos dos cursos de Educação Física da Faculdade Anhanguera de São Luís. Trata-se do primeiro passo rumo a uma longa trajetória de incentivo à produção científica dos alunos do curso, oportunizando assim a publicação dos Trabalhos de Conclusão de Curso em uma edição rica de temas variados na área da Educação Física. O conteúdo versa sobre temas que abrangem esporte, educação física escolar, saúde, treinamento, doenças crônicas e atividade física.