bluuebunny/crossref_metadata_2025_split huggingface dataset:
Social Hygiene in the USSR as a Scientific Discipline (1922-1930): German Influence, Zemstvo Experience and State Patronage
Authors: Кирик Ю.В. , Ратманов П.Э. 
Published: October 2023

Работа посвящена процессу становления советской социальной гигиены как научной дисциплины в условиях социалистических преобразований и трансферу идей из Германии и дореволюционной России в СССР в 1920-е гг. Научной основой социальной гигиены в СССР стала немецкая социальная гигиена (понятие, область знаний, специальные научные методы) и методология земской медицины. Научная область знаний и методы исследования в советской социальной гигиене полностью отражали идеологию А. Гротьяна, основателя немецкой социальной гигиены. Это исследование показывает, что формирование социальной гигиены в СССР происходило под непосредственным воздействием органов государственной власти.
The work is devoted to the process of formation of Soviet social hygiene as a scientific discipline under conditions of socialist transformations and the transfer of ideas from the Weimar Republic and pre-revolutionary Russia to the USSR in the 1920s. The scientific basis of social hygiene in the USSR was German social hygiene (concept, field of knowledge, special scientific methods) and the methodology of Zemstvo medicine. The scientific field of knowledge and research methods in Soviet social hygiene fully reflected the ideology of A. Grotjahn, the founder of German social hygiene. This study shows that the formation of social hygiene in the USSR took place under the direct influence of the state authorities.
Russian Peasantry in the Conditions of National Mobilization of 1914-1916: Gender Aspect
Authors: Поршнева О.С. 
Published: October 2023

В статье раскрываются особенности участия крестьянства в процессах национальной мобилизации в России в 1914–1916 гг. Показаны гендерно-дифференцированные реакции крестьян на вступление страны в войну и способы адаптации к военной повседневности, формы крестьянского участия в усилиях домашнего фронта. Проанализированы последствия изменения гендерной ситуации в связи с мобилизацией мужчин-домохозяев и новой социальной ролью солдатки, новые гендерные практики и отношение к ним крестьян. Раскрыты особенности восприятия крестьянами патриотической пропаганды, формы ментальных и поведенческих реакций на информацию о состоянии фронта и тыла, роль гендерных образов и языка в низовом дискурсе. Показана роль крестьянки, на чьи плечи легла вся тяжесть труда по поддержанию семьи и домохозяйства, в нарастании недовольства продовольственной политикой правительства, главным проявлением которого стали «бабьи бунты». Сделан вывод о том, что ментальные реакции, социальные и гендерные практики крестьянства в условиях войны продемонстрировали пределы политической мобилизации российского общества, не завершившего социокультурную трансформацию.
The article reveals the features of the participation of the peasantry in the processes of national mobilization in Russia in 1914-1916. The gender-differentiated reactions of peasants to the country's entry into the war and ways of adapting to military everyday life, forms of their participation in the home front efforts are shown. The consequences of changing the gender situation in connection with the mobilization of male householders and the new social role of the soldatki, new gender practices and the attitude of the peasants towards them are analyzed. The peculiarities of peasants' perception of patriotic propaganda, forms of mental and behavioral reactions to information about the state of the front and rear, the role of gender images and language in grassroots discourse are revealed. The role of a peasant woman, on whose shoulders all the hard work of maintaining a family and household fell, in the growing discontent with the government food policy, the main manifestation of which were “women's riots”, is shown. It is concluded that the mental reactions, social and gender practices of the peasantry in the conditions of war demonstrated the limits of the political mobilization of Russian society, which has not completed the socio-cultural transformation.
Historiographical Symphony by Professor Valentina P. Korzun
Authors: Леонтьева О.Б. , Мягков Г.П. , Репина Л.П. 
Published: October 2023

Статья посвящена интеллектуальной биографии и основным вехам научной деятельности известного российского историка, основателя омской историографической школы профессора Валентины Павловны Корзун. Выделены стержневые темы научных трудов В.П. Корзун: личность историка, профессиональная рефлексия и экзистенциальный выбор, научные коммуникации и научные сообщества, генезис интеллектуальной истории в отечественной традиции. Охарактеризован вклад В.П. Корзун в развитие отечественной историографии: введение в научный оборот ранее неизвестных историографических источников, разработка эпистемологических проблем исторического знания и методологических подходов к изучению научных коммуникаций, а также ее роль в становлении региональной историографической школы.
The article is devoted to the intellectual biography and scientific activity of the famous Russian historian, the founder of the Omsk historiography school, Prof. Valentina P. Korzun. The core topics of her works: the personality of a historian, professional reflection and existential choice, research communities, the genesis of intellectual history in the national tradition. The contribution of V.P. Korzun in the Russian historiography: the introduction of new sources into scientific circulation, the elaboration of epistemological problems and new approaches to the study of scientific communications, her role in the formation of the regional school of historiography.
Mulheres na área STEM
Authors: Roselle Leihge , Maciel Cristiano 
Published: October 2023

Trata-se de uma resenha sobre o livro Success strategies from women in STEM: a portable mentor, que possui como editoras as pesquisadoras Peggy A. Pritchard e Christine S. Grant. Essas são mulheres cientistas que, respectivamente, atuam como educadora na University of Guelph e professora universitária de Engenharia Química e Biomolecular na NC State University. A obra foi publicada em 2015 pela Editora Elsevier, e aborda temas relacionados ao desenvolvimento de carreira das mulheres que atuam na área de Science Technology Engineering and Math (STEM), focalizando as carreiras que são desenvolvidas dentro das universidades, nomeadas de acadêmicas.
LncRNA/CircRNA-miRNA-mRNA Axis in Atherosclerotic Inflammation:
Research Progress
Authors: Lv Nuan , Zhang Yilin , Wang Luming , Suo Yanrong , Zeng Wenyun , Yu Qun , Yu Bin , Jiang Xijuan 
Published: October 2023

Abstract:
Atherosclerosis is characterized by chronic inflammation of the arterial wall. However,
the exact mechanism underlying atherosclerosis-related inflammation has not been fully elucidated.
To gain insight into the mechanisms underlying the inflammatory process that leads to
atherosclerosis, there is need to identify novel molecular markers. Non-coding RNAs (ncRNAs),
including microRNAs (miRNAs), long non-protein-coding RNAs (lncRNAs) and circular RNAs
(circRNAs) have gained prominence in recent years. LncRNAs/circRNAs act as competing endogenous
RNAs (ceRNAs) that bind to miRNAs via microRNA response elements (MREs),
thereby inhibiting the silencing of miRNA target mRNAs. Inflammatory mediators and inflammatory
signaling pathways are closely regulated by ceRNA regulatory networks in atherosclerosis.
In this review, we discuss the role of LncRNA/CircRNA-miRNA-mRNA axis in atherosclerotic
inflammation and how it can be targeted for early clinical detection and treatment.
Pharmacoeconomic Aspects of Diabetes Mellitus: Outcomes and Analysis
of Health Benefits Approach
Authors: Baishnab Suman , Jaura Ravinder Singh , Sharma Saksham , Garg Honey , Singh Thakur Gurjeet 
Published: October 2023

Abstract:
Pharmacoeconomics is an important tool for investigating and restructuring healthcare
policies. In India, recent statistical studies have shown that the number of diabetic patients is
rapidly increasing in the rural, middle and upper-class settings. The aim of this review is to call
attention towards the need to carry out pharmacoeconomic studies for diabetes mellitus and
highlight the outcome of these studies on healthcare.

:
A well-structured literature search from PubMed, Embase, Springer, ScienceDirect, and
Cochrane was done. Studies that evaluated the cost-effectiveness of various anti-diabetic agents
for type 2 diabetes were eligible for inclusion in the analysis and review. Two independent
reviewers sequentially assessed the titles, abstracts, and full articles to select studies that met the
predetermined inclusion and exclusion criteria for data abstraction. Any discrepancies between
the reviewers were resolved through consensus.

:
By employing search terms such as pharmacoeconomics, diabetes mellitus, cost-effective
analysis, cost minimization analysis, cost-utility analysis, and cost-benefit analysis, a total of 194
papers were gathered. Out of these, 110 papers were selected as they aligned with the defined
search criteria and underwent the removal of duplicate entries.

:
This review outlined four basic pharmacoeconomic studies carried out on diabetes mellitus. It
gave a direction that early detection, patient counseling, personalized medication, appropriate
screening intervals, and early start of pharmacotherapy proved to be a cost-effective as well as
health benefits approach.
An Exquisite Analysis on the Significance of Nutrient Supplementation in
the Holistic Management of Poly-cystic Ovarian Syndrome
Authors: Pal Rashmi Saxena , Pal Yogendra , Lalitha Chaitanya Motamarri Venkata Naga , Kumar Rajnish , Tyagi Pankaj , Srivastava Preeti 
Published: October 2023

Abstract:
The complex heterogeneous disorder known as polycystic ovarian syndrome (PCOS) includes endocrine, reproductive, metabolic, psychological, and other pathological aspects. Yet,
nothing is understood regarding the cause of PCOS. Insulin resistance and hyperandrogenism are
major contributors to the pathophysiology of PCOS, according to various studies. Because of this,
a lot of PCOS treatment regimens include changing a person's lifestyle through practices, like exercise, nutrition, and vitamin supplementation. Recent studies have indicated a number of nutrients,
including vitamins, minerals, and vitamin-like substances, for the therapy of PCOS since they all
have at least one functional characteristic in the pathways that are affected by PCOS. As a result,
it is claimed that PCOS may be caused by a vitamin or mineral deficiency. It is the goal of this review to conduct a critical literature analysis on nutritional supplementation for the management of
PCOS.
Reasons for Requesting Ultrasonography: A Retrospective Study
Authors: Bagci Nuray , Peker Ilkay 
Published: October 2023

Objective:
The aim of this study is to evaluate (i) the reasons for requesting ultrasonography (USG) in a dentistry faculty and (ii) the scanning regions, the
type of probe used, and the use of Doppler USG.

Methods:
USG request forms of patients who applied to our radiology clinic for USG were analyzed retrospectively. According to the clinical information of
the patients in the request forms, the reasons for requesting USG were divided into four groups: soft tissue swelling, soft tissue calcification, lymph
node, and other examinations. Data were statistically compared between sex (female and male) and age groups (≤40−years−old and
˃40−years−old).

Results:
The USG request forms of 50 patients were obtained. The mean patient age was 45.06±14.50 years. Twenty-six patients were female (52%), while
twenty-four patients were male (48%). Soft tissue swelling, soft tissue calcification, lymph node, and other examinations were noted as the reasons
for requesting USG in 42%, 26%, 18%, and 14% of the patients, respectively. The most scanned regions were the submandibular (56%), parotid
(16%), and cheek (10%) regions. Extraoral probe was used more frequently than intraoral probe (78% vs. 22%). Doppler USG was used in most
patients (98%). A statistically significant difference was found between age groups and calcification examination (p<0.05).

Conclusion:
The reasons for requesting USG were mostly soft tissue swelling, soft tissue calcification, and lymph node examinations. The most commonly
scanned region and used type of probe were the submandibular region and extraoral probe, respectively. Doppler USG was used in most patients.
Non-neoplastic Liver Lesions after Biliary Stenting: Gadoxetic Acid-enhanced
MRI Findings and Clinical association
Authors: Ihara Kenichiro , Tanabe Masahiro , Ueda Takaaki , Kobayashi Taiga , Higashi Mayumi , Ito Katsuyoshi 
Published: October 2023

Background::
Non-neoplastic liver lesions that show low signal intensity in the hepatobiliary phase (HBP) of gadoxetic acid-enhanced magnetic resonance imaging (EOB-MRI) after biliary stenting and require differentiation from liver metastases may be seen.

Objective::
To evaluate the imaging findings and clinical association of non-neoplastic liver lesions showing hypointensity in the HBP of EOB-MRI after biliary stenting, and assess their differentiation from liver metastases.

Methods::
This study included 30 patients who underwent EOB-MRI after biliary stenting for pancreatobiliary malignancies. Among these, 7 patients had pathologically diagnosed non-neoplastic liver lesions which appeared hypointense in the HBP, and were categorized into the non-neoplastic group. The remaining 23 patients without non-neoplastic liver lesions were included in the control group. Additionally, 29 patients with liver metastasis were included as the liver metastasis group. Clinical associations and imaging features were compared between the groups.

Results::
A history of cholangitis and two or more biliary interventional procedures were significantly more frequently observed in the non-neoplastic group (p=0.002 and p=0.01, respectively) than in the control groups. Regarding the imaging findings, the liver to lesion signal intensity ratio in the HBP in the liver metastasis group was significantly higher than that in the non-neoplastic group (2.13 vs. 1.53, p=0.002). Additionally, liver metastases were visualized significantly more clearly on diffusion-weighted images (p=0.033) and HBP images (p&amp;amp;lt;0.001) in comparison to non-neoplastic lesions.

Conclusion::
Non-neoplastic liver lesions, probably due to biliary inflammation, may be observed in the HBP of EOB-MRI in patients after biliary stenting. These lesions may be associated with a history of cholangitis and repeated biliary intervention procedure, and need to be differentiated from liver metastases.
An Optimal Model Combining SqueezeNet and Machine Learning Methods for
Lung Disease Diagnosis
Authors: Maiti Abdallah , Abarda Abdallah , Hanini Mohamed , Oussous Ahmed 
Published: October 2023

Background:
Artificial intelligence (AI) is rapidly evolving in healthcare, with transformative potential. AI revolutionizes medical imaging by enabling online
self-diagnosis for patients and improving diagnostic accuracy for healthcare professionals. While valuable datasets aid machine learning in disease
detection, challenges persist in diagnosing similar lung conditions from chest X-rays. Integrating AI into healthcare holds promise for enhanced
outcomes and efficiency.

Objective::
In this article, we aim to present a new AI model that solves this challenge by allowing the differentiation, diagnosis and classification of three
distinct diseases, whose symptoms are very similar. The fundamental contribution is to reduce the number of parameters used while maintaining
the same level of precision for use in embedded systems.

Methods::
Our proposed model combines the power of the neural network using the SqueezeNet architecture with a set of machine learning algorithms as
classifiers, including logistic regression, support vector machine (SVM), k-nearest neighbors (KNN), decision tree, and naive Bayes. The chest Xray
dataset used in the proposed model consists of CXR images that are classified into four categories: pneumonia, tuberculosis, COVID-19, and
normal cases.

Results::
Our proposed model demonstrated remarkable accuracy (97,32%), precision (97,33), F1 score (97,31%), recall (97,30%), and AUC (99,40), which
is close to the best model. Whereas, the number of parameters used by our model (4,6 M) is very small compared to the best model in the literature
(47M).

Conclusion::
The model demonstrated good classification accuracy. In addition, the proposed model has the ability to use fewer parameters, which means it
requires less internal memory and computing resources.
Synchronous Double Primary Malignant Tumors and their Possible Shared
Genes: A Rare Clinical Entity
Authors: Hu Na , Yan Gang , Tang Mao-wen , Wu Yu-hui , Xiang Yi-ning , Lei Ping-gui 
Published: October 2023

Objective:
This study sought to analyze the 18F-FDG PET/CT and contrast-enhanced computed tomography (CT) images of synchronous colorectal cancer
(CRC) and renal clear cell carcinoma (ccRCC) and identify the shared genes between these two types of cancer through bioinformatic analysis.

Methods:
A retrospective analysis was conducted on a patient with synchronous CRC and ccRCC who underwent 18F-FDG PET/CT and contrast-enhanced
CT before treatment. Databases were analyzed to identify differentially expressed genes between CRC and ccRCC, and co-expression genes were
extracted for RCC and CRC.

Results:
18F-FDG PET/CT revealed intense metabolic activity in the primary colorectal lesion (SUVmax 13.2), while a left renal mass (diameter = 35 mm)
was observed with no significant uptake. Contrast-enhanced CT during the arterial phase showed heterogeneous intense enhancement of the renal
lesion, and the lesion washed out earlier than in the renal cortex in the nephrographic and excretory phases, indicating ccRCC. The
histopathological results confirmed synchronous double primary malignant tumors. Our bioinformatic analysis results showed that synchronous
occurrence of CRC and ccRCC may correlate with simultaneous expression of Carbonic Anhydrase 9 (CA9), integrin-binding sialoprotein (IBSP),
and Fibrinogen γ chain (FGG).

Conclusion:
18F-FDG PET/CT combined with contrast-enhanced CT is an effective diagnostic tool in evaluating synchronous CRC and RCC. By analyzing this
clinical case and conducting bioinformatic analysis, we improved our current understanding of the mechanisms underlying synchronous tumors.

other:
no
A Review on the Use of Gold Nanoparticles in Cancer Treatment
Authors: Sultana Razia , Yadav Dhananjay , Puranik Nidhi , Chavda Vishal , Kim Jeongyeon , Song Minseok 
Published: October 2023

Abstract:
According to a 2020 WHO study, cancer is responsible for one in every six fatalities. One in four patients
die due to side effects and intolerance to chemotherapy, making it a leading cause of patient death. Compared
to traditional tumor therapy, emerging treatment methods, including immunotherapy, gene therapy, photothermal
therapy, and photodynamic therapy, have proven to be more effective. The aim of this review is to highlight
the role of gold nanoparticles in advanced cancer treatment. A systematic and extensive literature review
was conducted using the Web of Science, PubMed, EMBASE, Google Scholar, NCBI, and various websites.
Highly relevant literature from 141 references was chosen for inclusion in this review. Recently, the synergistic
benefits of nano therapy and cancer immunotherapy have been shown, which could allow earlier diagnosis, more
focused cancer treatment, and improved disease control. Compared to other nanoparticles, the physical and optical
characteristics of gold nanoparticles appear to have significantly greater effects on the target. It has a crucial
role in acting as a drug carrier, biomarker, anti-angiogenesis agent, diagnostic agent, radiosensitizer, cancer immunotherapy,
photodynamic therapy, and photothermal therapy. Gold nanoparticle-based cancer treatments can
greatly reduce current drug and chemotherapy dosages.
Anti- SARS-CoV-2 IgG and IgM Levels in Iraqi General Population
Authors: Alobaidi Amina Hamed , Mustafa Hussein Inam , Salih Ahmed Mutar , Alsamarai Abdulghani Mohamed 
Published: October 2023

Background:
Acquired immunity plays an important role in the prevention of viral infec-tions. SARS-CoV-2 is an infection that leads to a pandemic. The development of specific anti-SARS-CoV-2 antibodies may play a vital role in disease prevention and control. Thus IgG antibody screening in the general population provides information on the immunological status of the community

Aim:
To clarify the SARS-CoV-2 immune status in the general population.

Methods:
A cross-sectional study was conducted in Kirkuk province during the period from 15 May 2022 to 11 September 2022. The samples were collected from voluntary subjects and informed con-sent was taken from each participant before their enrolment in the study. SARS-CoV-2 IgG, SARS-CoV-2 IgM, 25-OH Vitamin D, Vitamin B12, and Folate were determined using the Electrochemi-luminescence Immunoassay (eCLIA) technique with the instrument NIPIGON-Robot R1Automated ECL Analyzer (Canada).

Results:
The overall IgG mean concentration was 37.75 ± 23.18 COI, with a median of 39.99 COI and a range of 0.25 - 87.23 COI. Additionally, 93% of tested samples were with concentrations of more than 1 COI. The highest frequency (18.2%) was for the IgG concentration of 51 to 60 COI, while the lowest frequency (1.3%) was for the concentration of 81 - 90 COI. The IgG was signifi-cantly higher (P = 0.046) in males (39.87 ± 24.04 COI) than that in females (35.12 ± 21.89 COI). The IgM overall concentration was 0.569 ± 0.456 COI, with a median of 0.489 COI and a range of 0.17 - 6.40 COI. The mean serum level of folic acid concentration was 9.03 ± 5.72 ng/ml, with a median of 7.476 ng/ml and a range of 0.60 - 20.00 ng/ml. The mean serum concentration of vitamin B12 was 462.65 ± 349.18 pg/ml, with a median of 353 pg/ml and a range of 13.05 - 2000 pg/ml. The mean serum concentration of vitamin D was 18.29 ± 18.42 ng/ml with a median of 12.44 ng/ml and a range of 3 - 100 ng/ml. IgG and IgM serum levels did not show a significant correlation with serum levels of folic acid, vitamin D, and vitamin B12. However, there was a significant correlation between folic acid and vitamin D (r = 0.197; P = 0.012); vitamin B12 and vitamin D (r = 0.253, P = 0.001). While there was a non-significant correlation between folic acid and vitamin D serum levels (r = 0.129, P = 0.10).

Conclusion:
General population IgG antibody concentration reflects a high rate of herd immunity. Folic acid was with a mean value of about half of the upper normal limit and only 17.7% were with low values. Vitamin B12, only 6.3% of the population had values lower than normal. However, the range of vitamin B12 was wide. While vitamin D values were lower than the normal limit at 82.6%. However, a large scale well designed was warranted to evaluate COVID-19 national immune re-sponse.