bluuebunny/crossref_metadata_2025_split huggingface dataset:
Menstrual pattern changes following minilap/pomeroy, minilap/ring and laparoscopy/ring sterilization: A review of 5982 cases
Authors: Bhiwandiwala Pouru P. , Mumford Stephen D. , Feldblum Paul J. 
Published: April 2004

AbstractMenstrual pattern changes experienced by 5982 women subsequent to sterilization by the techniques of minilap/Pomeroy, minilap/tubal ring and laparoscopy/tubal ring were tabulated. Controlling for prior contraceptive use, we examined data on the following six menstrual parameters at the time of sterilization compared to reports at follow‐up visits 6 and 12 months after surgery: cycle regularity, cycle length, menstrual flow duration, amount of flow, dysmenorrhea and intermenstrual bleeding. Our findings suggest that minilap sterilization does not cause menstrual pattern changes.
Treatment of fibrocystic disease of the breast with gestrinone, a new trienic synthetic steroid with anti‐estrogen, anti‐progesterone properties
Authors: Coutinho E.M. , Azadian‐Boulanger G. 
Published: April 2004

AbstractTwenty‐eight patients with radiologically diagnosed fibrocystic disease were given twice weekly 5 mg tablets of Gestrinone, a synthetic contraceptive steroid with potent anti‐estrogen, anti‐progesterone properties, for periods ranging from 3 to 9 months. Treatment was discontinued when the nodularity disappeared and the patient became asymptomatic. Twelve patients had palpable nodules or masses in both breasts, while the remaining 16 had a single nodule or lump. In 12 patients, all with small nodules or lumps, complete elimination of nodularity occurred at the end of the first 3 months of treatment. In a further eight patients, five of whom had small nodules and three of whom had large ones, an additional 3 months of therapy were required to achieve complete elimination of nodularity. In two subjects, nodularity was eliminated at the end of 9 months of therapy, and in the remaining six subjects, although a reduction in nodularity greater than 50% occurred, masses remained palpable at the end of 9 months. Pain and tenderness were eliminated during the first 2 weeks of therapy in most cases. The most common complaints were acne and seborrhea (70% of patients) and a weight gain of between 2 and 5 kg in patients treated for 9 months. Main side effects encountered were acne and seborrhea.
Menstrual regulation with prostaglandin (Pg ONO 802) in Indonesia
Authors: Agoestina T. , Sastrawinata Sulaiman , Prayitno Wasis , Gonta Pim 
Published: April 2004

AbstractThis study was conducted to evaluate the safety, efficacy and acceptability of PGE1 vaginal suppositories (Pg ONO 802) in menstrual regulation. Each vaginal suppository contains 1 mg of 16,16 dimethyl‐trans‐Δ2 PGE1 methyl ester. Five suppositories were inserted as high as possible into the fornix posterior of the vagina at intervals of 3 h. Five hundred thirty four subjects with delay of menses mostly of up to 14 days were included in the study. Blood chemistry was evaluated and urine analysis performed in all subjects. Success of treatment was assessed on two alternative groups of criteria: (A) induction of bleeding by Pg ONO 802; (B) induction of bleeding achieved by Pg ONO 802 and not followed by surgical intervention. The success rate based on criteria A was 98.9%, and on criteria B 86%. If heavy bleeding occurred and signs of pregnancy were found during the trial period, intervention was made by vacuum aspiration or curettage when necessary. If bleeding did not occur and/or pregnancy continued, treatment was declared a failure and pregnancy was terminated by vacuum extraction or curettage. For non‐pregnant subjects no intervention was made but careful re‐evaluation was carried out. Mean duration of bleeding after Pg ONO 802 treatment was 6.7 days. Side‐effects were generally mild. The incidence of diarrhea was 8.8%, nausea 7.8%, headache 5.8%, vomiting 2.8%; abdominal cramp occurred in as many as 66% of subjects. No treatment was given for these side‐effects as they were within acceptable limits. The onset of side‐effects mostly occurred between insertion of the 1st and 2nd (46.7%) suppositories and onset of bleeding at the time of insertion of the 2nd suppository (41.6%).
Carcinoembryonic antigen in high risk pregnancies
Authors: Lolis D. , Baltoyiannis P. , Messinis I.E. 
Published: April 2004

AbstractThe significance of carcinoembryonic antigen (CEA) measurement was evaluated in 25 pregnant women with diabetes mellitus, 15 Rh negative sensitized and nine prolonged pregnancies. Another 114 women with normal pregnancy served as controls. Values in maternal and umbilical cord serum and in amniotic fluid did not change appreciably through 24–42 weeks' gestation. No significant difference in maternal serum, cord serum and amniotic fluid CEA values was found between diabetic, Rh negative sensitized and normal pregnancies at the corresponding weeks. Similar findings were obtained in prolonged pregnancies, except the values in amniotic fluid which were significantly higher than in normal pregnancies due to the presence of meconium. These results suggest that the measurement of CEA in high risk pregnancies is not useful in predicting fetal condition.
Human chorionic gonadotropin in the ectopic gestation
Authors: Golan Abraham , Van Der Walt Andree L. , Wexler Shraga , Kort Hilton 
Published: April 2004

AbstractThe ectopic pregnancy is a relatively common condition in the south African black patients. The beta‐specific subunit radioimmunoassay for human chorionic gonadotrophin (HCG) was utilized in procuring information in our series of 30 patients. Levels of the hormone were significantly lower when compared to normal gestation of similar duration, never exceeding 2000 mIU/ml. The clearance rate of HCG following normal vaginal delivery was about 24 h and less variable than that of ectopic gestation. The half‐life clearance rate of HCG in the ectopics could be divided into three phases, suggestive of HCG compartmentalization. The possible buffering effect of this hormone in the maintenance of the receptor‐saturated pregnancy is discussed. The possibility that the HCG produced by the normal pregnancy is dissimilar to that of ectopic is speculated upon.
The effects of cyclofenil on the cervical mucus score (Insler)
Authors: Bhathena R.K. , Patel R.H. , Varma T.R. 
Published: April 2004

AbstractDaily simultaneous cervical mucus evaluation and ultrasonography of the Graafian follicular growth an ovulation were studied (in the mid‐cycle) in 8 infertile British women during 30 Cyclofenil‐stimulated cycles, and compared with 18 non‐stimulated normal ovulatory cycles in 12 subjects (controls). In the 16 Cyclofenil‐induced ovulatory cycles, there was an early (5 days prior to the day of ultrasonic ovulation) Full Cervical Mucus Score (Insler) in 69% of the cycles, and the Full Cervical Mucus Score lasted for 7 days or more in 63% of the cycles. In 38%, there was persistence of the Full Cervical Mucus Score on the third day after ultrasonic ovulation. In the 14 Cyclofenil‐treated an ovulatory cycles, a Full Cervical Mucus Score was recorded on one or more occasions in the mid‐cycle in 29% of the cycles. The classical teaching of prediction of the probable timing of ovulation by Cervical Mucus Scoring is not applicable to Cyclofenil‐stimulated cycles.
Effect of hormone replacement therapy on anti‐thrombin III activity in post menopausal women
Authors: Varma T.R. , Patel R.H. , Rosenberg D. 
Published: April 2004

AbstractAnti‐thrombin III is the major inhibitor of activated blood clotting factors. We studied 320 patients with climacteric symptoms who received estrogen replacement therapy to assess the effect of hormone therapy on Anti‐thrombin III (AT‐III) activity). Of the 320 patients 80 patients received Prempak C (0.625 mg) for 2 years, 82 patients received Prempak C (1.25 mg) for 2 years, 78 patients received Cycloprogynova (1 mg) for 2 years and the remaining 80 patients received Cycloprogynova (2 mg) for 2 years. The mean AT‐III activity before, during and 3 months after treatment showed no significant difference in all the four groups of patients. There was no incidence of myocardial infarction or stroke or thrombo‐embolic disease in this group of 320 patients receiving estrogen replacement therapy.
Life threatening complications of endometriosis
Authors: Marineau E.J. , Deppe G. , Sokol R.J. , Malviya V.K. , Adel S.K. 
Published: April 2004

AbstractEndometriosis affects 5–20% of menstruating women and occurs primarily within the pelvis. Although histologically benign, ectopic endometrial tissue possesses the ability to grow, infiltrate and disseminate with life threatening results/consequences. This is illustrated by a case of asymptomatic endometriosis involving the ureters and rectum. The importance of evaluating the integrity of the urinary tract in endometriosis, especially cases involving the uterosacral ligaments, is stressed. Appropriate therapy followed by periodic surveillance for progression of the disease is discussed.
Fatal heart monitoring and ultrasound in the management of placental abruption
Authors: Ito M. , Kawasaki N. , Matsui K. , Fujisaki S. 
Published: April 2004

AbstractThree cases of placental abruption with the “pseudosinusoidal” fetal heart rate (FHR) pattern, a periodic late deceleration related to frequent uterine contractions are reported. This ‘pseudosinusoidal’ pattern is clearly not a true sinusoidal pattern. The fetal monitoring patterns of these patients are presented and discussed along with the use of ultrasound in the management of this condition. All infants were delivered by cesarean section with low Apgar scores at birth, but they soon recovered completely.
Elevated intravesicular fluid thyroid‐stimulating hormone concentration in hydratidiform mole
Authors: Gunasegaram R. , Peh K.L. , Loganath A. , Kottegoda S.R. , Ratnam S.S. 
Published: April 2004

AbstractIn an attempt to explain hyperthyroidism in hydatidiform mole, concentrations of immunoreactive thyroid‐stimulating hormone (TSH) together with human‐chorionic gonadotrophin (β‐hCG) were measured in the serous fluid obtained from 43 patients aged 15–45 years and with amenorrhea 11–31 weeks. Elevated concentrations of these two hormones were found in all samples. It is probable that hyperthyroidism could stem from TSH immunologically similar to pituitary TSH and distinct from hCG and luteinizing hormone (LH) that we have identified in hydatid vesicles.
Reproductive performance after eclampsia
Authors: Adelusi Babatunde , Ojengbebe O.A. 
Published: April 2004

AbstractEclampsia is a common complication of pregnancy in Ibadan, although its long term effects on subsequent pregnancies is unknown. In a prospective study of 64 women who had eclampsia in their previous pregnancies and were followed up in their current pregnancies, 15.6% of them had recurrent eclampsia, in spite of optimal antenatal care. Of the 18 patients with diastolic blood pressure of 80 mmHg 22.2% or over at booking had antepartum or intrapartum eclampsia as compared with only 2.2% of 46 patients with diastolic blood pressure of less than 80 mmHg at booking. This finding was statistically significant (P < 0.01), showing that the diastolic blood pressure at booking can be a measure of the potential for developing eclampsia because of the possibility of residual hypertension on which pre‐eclampsia may be superimposed. Similarly, there was a significant association (P < 0.05) between the birthweight of the babies and the diastolic blood pressure at booking, and may be a measure of the effect of vascular effect of pre‐eclampsia on the placenta. However, there was no difference in the perinatal mortality rate in this study and the overall hospital figures in spite of the high risk pregnancies being managed. It was concluded, therefore, that the outcome of these pregnancies would depend much on the standard of antenatal care provided for the patients.
Viral hepatitis as a major cause of maternal mortality in Addis Ababa, Ethiopia
Authors: Kwast B.E. , Stevens J.A. 
Published: April 2004

AbstractCauses of maternal mortality were investigated in Addis Ababa, Ethiopia, from September 1981 to September 1983. Viral hepatitis ranked third among the leading causes of maternal mortality behind septic abortion and puerperal sepsis. There were 26 deaths from viral hepatitis during the 2‐year study period for a hospital maternal mortality rate of 91.0 per 100,000 live births. Although 30% of women who died of all maternal causes received antenatal care in Addis Ababa, only 13% of women who died from viral hepatitis in our hospital study received antenatal care. Low socio‐economic status (SES) has been shown to be associated with low antenatal care utilization and with an increased risk of protein malnutrition. Malnutrition is considered a predisposing factor for liver damage. Suggestions for reducing hepatitis transmission and maternal mortality through education, better hygiene, and improved sanitation are discussed.
Estrogen receptors in breast cancer ‐ therapeutic response to the treatment of recurrences
Authors: Pinotti J.A. , Teixeira L.C. , Pisani R.C.B. , Bastos S.R. 
Published: April 2004

AbstractThe authors analyze estrogen receptors in 501 cases of breast cancer and the therapeutic response achieved with treatment of patients who relapsed. The method utilized to determine the presence of estrogen receptor was cytosol protein‐counting and Dextran coated charcoal (DCC) saturation analysis. Patients were treated with chemotherapy when the primary tumor was estrogen‐receptor negative. If receptor was present, anti‐estrogen drug (Tamoxifen) was added. Patients previously treated with the anti‐estrogen presented a better response to anti‐estrogen therapy and a lower recurrence rate. Recurrences were more frequent in estrogen receptor negative cases and better responses to treatment were found in estrogen receptor positive ones.
Prophylactic topical cefamandole in radical hysterectomy
Authors: Miyazawa K. , Hernandez E. , Dillon M.B. 
Published: April 2004

AbstractFrom July 1, 1978 to June 30, 1984, 45 radical abdominal hysterectomies were performed by the authors at Tripler Army Medical Center. Management was uniform except for the use of prophylactic antibiotics. Three patterns of practice were identified: Group I, no antibiotics were used; Group II, intravenous (i.v.) antibiotics were given in the induction room and for less than 48 h post‐surgery; Group III, prophylactic i.v. antibiotics were given and the surgical site was also irrigated with a cefamandole and saline solution. The three groups were found to be similar with regard to age, parity, weight‐height index, pre‐ and postoperative hematocrit, pre‐operative white blood cell count, operative and anesthesia times, estimated blood loss, and amount of blood transfused. Groups I and II had a higher surgical site infection rate (87.5% and 63.6%, respectively) than Group III (3.8%). The mean 10‐day fever index in degree hours was 109 for Group I, 71 for Group II, and 30 for Group III (P < 0.001). Irrigation of the surgical site with a cefamandole and saline solution in addition to i.v. antibiotics decreases the infectious morbidity of radical hysterectomy.
In vitro studies on the control of human myometrial gap junctions
Authors: Garfield R.E. , Hayashi R.H. , Harper M.J.K. 
Published: April 2004

AbstractIn this study human myometrial tissues were examined for the presence of gap junctions by quantitative electron microscopy before and after incubation in tissue culture media with and without indomethacin. The area of gap junctions was very low in tissues from pregnant women at term but not labor, before incubation. After 24 and 48 h incubation without any treatment, segments of some of the same tissues developed many gap junctions and other tissues contained few junctions. Prostaglandin E (PGE), prostaglandin F (PGF) and prostaglandin F metabolite (PGF metabolite) levels in the media at various times were measured by radioimmunoassay. The prostaglandins increased progressively during the incubation period. Treatment of tissues with indomethacin decreased prostaglandin levels in the media and increased the numbers of gap junctions in those control tissues that developed few junctions over the same incubation interval. We conclude that the capacity of human myometrial tissues to develop gap junctions in vitro may depend upon a maturational stage in preparation for labor. Furthermore, our results suggest that products of the cyclo‐oxygenase or lipoxygenase pathways may control the presence of gap junctions in the human myometrium and that changes in synthesis in these patterns may occur as part of the maturational process.
Ultrasonically guided follicle aspiration for oocyte retrieval in an in vitro fertilization program: Further simplification
Authors: Sterzik K. , Jonatha W. , Keckstein G. , Rossmanith W. , Traub E. , Wolf A. 
Published: April 2004

AbstractTransabdominal, transvesical aspiration of oocytes was performed in 58 infertility patients under ultrasound guidance. In contrast to other groups, no particular guiding instruments were used. Wider bore needles and general anesthesia improved the oocyte recovery rate from 44% to 80%, thus approaching the one achieved by laparoscopy.
The use effectiveness of the copper T‐200 in Matlab, Bangladesh
Authors: Rob U. , Phillips J.F. , Chakraborty J. , Koenig M.A. 
Published: April 2004

AbstractUsing a unique record keeping system, the use effectiveness of the Copper T‐200 is examined in rural Bangladesh. In Matlab the Copper T‐200 is a highly effective contraceptive modality. The adopters are typically low to medium parity women under 30 years of age. The most important cause of termination among women in the study was voluntary removal of the device. The complaint most often reported was bleeding followed by pain and weakness. The Matlab experience suggests that sustained motivation and regular resupply are the two key components of this highly successful family planning program.
Antepartal fetal death of one twin
Authors: Lumme R. , Saarikoski S. 
Published: April 2004

AbstractTwenty‐four cases with antepartal fetal death of one twin are reported. Of the still‐born fetuses 5 were delivered as a fetus papyraceus, 13 had severe and 6 no maceration. The cesarean section rate was 25%. The placenta was monochorionic in 12 cases. Structural defects were found in one monochorionic co‐twin of a fetus papyraceus. Otherwise the neonatal morbidity of the liveborn co‐twins was not increased if the low gestational age averaging 34 weeks, was taken into account. No manifestations of defective hemostasis were observed in the mothers.
The epidemiology of cancer of the uterine corpus in Canada: 1950–1985
Authors: Ayiomamitis A. 
Published: April 2004

AbstractMorbidity and mortality patterns in Canada from malignancies of the corpus uteri, were analyzed for the periods 1970–1980 and 1950–1985, respectively. Although rates of morbidity have fluctuated between 15.0 and 19.6 new cases per 100,000 population per year, age‐specific rates for women aged 35–44 have declined significantly (0.26 fewer new cases per 100,000 population per year; P < 0.05). Mortality rates have declined by approximately 50% between 1950 and 1985 (P < 0.0001) with age‐specific rates for women aged 35–44, 45–54, 55–64, 65–74 and 75–84 also exhibiting significant declines (P < 0.02).
Clearance pattern of maternal serum pregnancy specific β1‐glycoprotein after treatment in active and regressed tubal pregnancy
Authors: Phocas I. , Sarandakou A. , Kontoravdis A. , Chryssicopoulos A. 
Published: April 2004

AbstractThe clearance pattern of maternal serum pregnancy specific β1‐glycoprotein (SP1) was studied in 16 cases of tubal pregnancy (9 active and 7 regressed) after 12, 24, 48, 72, 96, 120 and 192 h following surgery. The mean values of the hormone in both groups showed a statistically highly significant difference in all measurements before and after treatment (P < 0.001), but they followed the same exponential regression pattern. The half‐life of SP1 in active tubal pregnancies after salpingectomy was 36.2 h and in regressed tubal pregnancies after salpingostomy was 37.5 h.
Maternity care in developing countries: Relevance of new technological advances
Authors: Faundes A. , Rosenfield A. , Pinotti J.A. 
Published: April 2004

AbstractIt is suggested that improved maternity care in the developing world depends primarily on the increased provision of cos‐effective basic, easily accessible maternity care services. Expensive new technologies should be judged by their effectiveness, safety, technical feasibility, cost (including operating and maintenance expenses) and local need. After identifying the major causes of morbidity and mortality, priority should be given to interventions applicable at the local level and which do not require highly or specially trained educated personnel.
Four‐year follow‐up of electrocoagulation and tubal ring sterilizations in Costa Rica
Authors: Cilenti D. , Solano A. , Aranda C. , Feldblum P.J. , Lamptey P.R. 
Published: April 2004

AbstractAn earlier analysis of 299 laparoscopic sterilizations comparing electrocoagulation and tubal ring occlusion techniques found no significant differences in rates of surgical complications. The risk of potentially serious complications, such as bowel/bladder burns, was considered higher with electrocoagulation suggesting that tubal rings might be the preferred technique. Examination of the same women through 48 months poststerilization showed no significant difference between the two techniques with respect to the incidence of gynecologic surgery performed subsequent to sterilization. Gynecologic abnormalities were similar for women in both groups. The rate of pregnancy was higher for tubal rings than for electrocoagulation (2.1 compared to 0.7 at 48 months) but this difference was not statistically significant.
A clinico‐pathologic study of ovarian neoplasm
Authors: Gopeesingh T.D. , Rahaman J. , Charran D. 
Published: April 2004

AbstractA series of 96 patients who were diagnosed with 120 ovarian neoplasms at surgery have been reviewed. Nine types of benign ovarian cysts were encountered. Benign cystic teratoma with an incidence of 30% was the commonest tumor. The majority of these were in the 20–30 year age range. The mean age of the patients with mucinous cyst adenoma and benign cystic teratoma was significantly less (P < 0.05) than those with serous cyst adenoma. The incidence of ovarian malignancies of 8.3% was low, and none of the malignancies was bilateral. There was a high incidence of 8.3% of malignant change in benign cystic teratomas. Abdominal pain and swelling were the symptoms most frequently experienced in patients with benign ovarian neoplasms.
Countrywide perinatal surveillance in Czechoslovakia
Authors: Štembera Z. 
Published: April 2004

AbstractCountrywide perinatal surveillance in four 10‐year periods of Maternal Child Health (MCH) care development in Czechoslovakia is described. During this time maternal mortality decreased from 137 to 17/100,000 live births, and perinatal mortality (PMR) from 51 to 12/1000. On the basis of study results, countrywide intervention strategies concerning organization as well as medical measures were gradually drawn up. The greatest decrease in PMR was found through basic perinatal care for all; greatest efficiency followed employment of a risk approach.
The role of confidential enquiries in the reduction of maternal mortality and alternatives to this approach
Authors: Cook R. 
Published: April 2004

AbstractThe aim of confidential enquiries into maternal deaths is to identify weaknesses in the maternal health care system with a view to remedying them. The method of confidential enquiry is explained using the British system as an example. The reasons why this apparently useful practice is not more widely adopted can in some countries include fears of litigation or lack of trust in confidentiality. Alternative approaches to maternal death audit are discussed.