bluuebunny/crossref_metadata_2025_split huggingface dataset:
Taste-Based Gender Favouritism in High-Stake Decisions: Evidence from The Price is Right
Authors: Atanasov Pavel , Dana Jason D , Klein Teeselink Bouke 
Published: October 2023

Abstract
Gender discrimination is present across various fields, but identifying the underlying mechanism is challenging. We demonstrate own-gender favouritism in a field setting that allows for clean identification of tastes versus beliefs: the One Bid game on the TV show The Price Is Right. Players must guess an item’s value without exceeding it, leaving the last bidder with a dominant ‘cutoff’ strategy of overbidding another player by ${\$}$1. We show that last bidders are significantly more likely to cut off opposite-gender opponents. This behaviour is explained by own-gender favouritism rather than beliefs that cutting off opposite-gender opponents is more profitable.
Characterization of de novo malignancy after orthotopic heart transplantation: single-centre outcomes over 20 years
Authors: Bakir Nadia H , Florea Ioana B , Phillipps Jordan , Schilling Joel D , Damiano Marci S , Ewald Gregory A , Kotkar Kunal D , Itoh Akinobu , Damiano Ralph J , Moon Marc R , Masood Muhammad F 
Published: October 2023

Abstract

OBJECTIVES
Malignancy is the leading cause of late mortality after orthotopic heart transplantation (OHT), and the burden of post-transplantation cancer is expected to rise in proportion to increased case volume following the 2018 heart allocation score change. In this report, we evaluated factors associated with de novo malignancy after OHT with a focus on skin and solid organ cancers.

METHODS
Patients who underwent OHT at our institution between 1999 and 2018 were retrospectively reviewed (n = 488). Terminal outcomes of death and development of skin and/or solid organ malignancy were assessed as competing risks. Fine–Gray subdistribution hazards regression was used to evaluate the association between perioperative patient and donor characteristics and late-term malignancy outcomes.

RESULTS
By 1, 5 and 10 years, an estimated 2%, 17% and 27% of patients developed skin malignancy, while 1%, 5% and 12% of patients developed solid organ malignancy. On multivariable Fine–Gray regression, age [1.05 (1.03–1.08); P &lt; 0.001], government payer insurance [1.77 (1.20–2.59); P = 0.006], family history of malignancy [1.66 (1.15–2.38); P = 0.007] and metformin use [1.73 (1.15–2.59); P = 0.008] were associated with increased risk of melanoma and basal or squamous cell carcinoma. Age [1.08 (1.04–1.12); P &lt; 0.001] and family history of malignancy [2.55 (1.43–4.56); P = 0.002] were associated with an increased risk of solid organ cancer, most commonly prostate and lung cancer.

CONCLUSIONS
Vigilant cancer and immunosuppression surveillance is warranted in OHT recipients at late-term follow-up. The cumulative incidence of skin and solid organ malignancies increases temporally after transplantation, and key risk factors for the development of post-OHT malignancy warrant identification and routine monitoring.
Isolated loss of the AUTS2 long isoform, brain-wide or targeted to Calbindin-lineage cells, generates a specific suite of brain, behavioral, and molecular pathologies
Authors: Song Yunshu , Seward Christopher H , Chen Chih-Ying , LeBlanc Amber , Leddy Analise M , Stubbs Lisa 
Published: October 2023

Abstract
Rearrangements within the AUTS2 region are associated with a rare syndromic disorder with intellectual disability, developmental delay, and behavioral abnormalities as core features. In addition, smaller regional variants are linked to wide range of neuropsychiatric disorders, underscoring the gene's essential role in brain development. Like many essential neurodevelopmental genes, AUTS2 is large and complex, generating distinct long (AUTS2-l) and short (AUTS2-s) protein isoforms from alternative promoters. Although evidence suggests unique isoform functions, the contributions of each isoform to specific AUTS2-linked phenotypes have not been clearly resolved. Furthermore, Auts2 is widely expressed across the developing brain, but cell populations most central to disease presentation have not been determined. In this study, we focused on the specific roles of AUTS2-l in brain development, behavior, and postnatal brain gene expression, showing that brain-wide AUTS2-l ablation leads to specific subsets of the recessive pathologies associated with mutations in 3′ exons (exons 8–19) that disrupt both major isoforms. We identify downstream genes that could explain expressed phenotypes including hundreds of putative direct AUTS2-l target genes. Furthermore, in contrast to 3′ Auts2 mutations which lead to dominant hypoactivity, AUTS2-l loss-of-function is associated with dominant hyperactivity and repetitive behaviors, phenotypes exhibited by many human patients. Finally, we show that AUTS2-l ablation in Calbindin 1-expressing cell lineages is sufficient to yield learning/memory deficits and hyperactivity with abnormal dentate gyrus granule cell maturation, but not other phenotypic effects. These data provide new clues to in vivo AUTS2-l functions and novel information relevant to genotype–phenotype correlations in the human AUTS2 region.
Toxoplasma gondii Causes Adverse Pregnancy Outcomes by Damaging Uterine Tissue-Resident NK Cells That Secrete Growth-Promoting Factors
Authors: Zhang Famin , Sun Wenze , Zhao Ji , Zhang Chenlin , Sheng Keyuan , Wang Cong , Song Lingling , Zhang Xiran , Cao Yuanyuan , Luo Qingli , Shen Jilong , Yu Li 
Published: October 2023

Abstract
Vertical transmission of the intracellular parasite, Toxoplasma gondii can lead to adverse pregnancy outcomes especially when infection occurs in early pregnancy. Decidual natural killer (dNK) cells accumulate at the maternal-fetal interface in large numbers during early pregnancy. Their nutritional roles during infection with T. gondii remain poorly defined. In the present study, we demonstrated that a functional deficiency of the uterine tissue-resident NK (trNK) cells, a subset of dNK cells, contributes to the adverse pregnancy outcomes induced by T. gondii in early pregnancy. Adverse pregnancy outcomes could be ameliorated by adoptive transfer of trNK cells. Moreover, fetal growth restriction could be improved after supplementation of growth-promoting factors. In addition to the widely recognized disturbance of the immune balance at the interface between the mother and the fetus, our study reveals a novel mechanism in T. gondii that contributes to the adverse pregnancy outcomes.
Requeening queenright honey bee colonies with queen cells in honey supers
Authors: Holmes Leslie A , Kearns Jeffery D , Ovinge Lynae P , Wolf Veiga Patricia , Hoover Shelley E 
Published: October 2023

Abstract
Many Canadian beekeepers replace a subset of their honey bee queens annually. However, introducing a new queen to a honey bee colony is a management practice with a high degree of uncertainty. Despite the consensus that it is most effective to introduce queens to queenless colonies, some commercial beekeepers claim success with introducing queen cells into the honey super of queenright colonies. We tested the success rate of this practice by introducing queen cells to 100 queenright colonies in southern Alberta during a honey flow. The genotypes of the resultant offspring drones were determined using the microsatellite marker A76 to identify their laying queen mothers. Our results show that new queens successfully supersede original queens in 6% of queenright colonies, suggesting that the practice does not result in the new queen taking over leadership in most colonies. Additionally, supersedure by daughter queens is more common (13%) than new queen supersedure when introducing queen cells to queenright colonies during a honey flow. However, there could be a benefit to the practice of requeening queenright colonies with queen cells in honey supers if the colonies that accepted a new queen (whether a daughter of or unrelated to the old queen) were colonies with a failing queen.
Causal Semantics for Implicative Verbs
Authors: Nadathur Prerna 
Published: October 2023

Abstract
Implicative verbs (e.g., manage, dare) are characterized by complement inferences (Karttunen, 1971). English manage entails its complement; the entailment reverses polarity with matrix negation, and is accompanied by a projective inference to the complement’s non-triviality (Coleman, 1975; Karttunen & Peters, 1979). I use data from Finnish and English to argue that the implicative inferential profile is derived from backgrounded relations of causal necessity and causal sufficiency (defined over the structure of a formal causal model; Pearl 2000; Schulz 2011) which link the lexical content of an implicative verb to the realization of its complement. The proposal builds on Baglini & Francez’s (2016) causal analysis of manage, but significantly revises the earlier proposal to offer a treatment which accounts not only for English manage, but extends to the lexical semantics of the full implicative class, including ‘polarity-reversing’ verbs like fail, lexically specific verbs like dare, and their Finnish counterparts. Unlike earlier analyses, the proposed causal semantics also provides a natural explanation of the commonalities between two-way entailing verbs like manage and a related class of weaker ‘one-way’ implicatives such as Finnish jaksaa (‘have the strength’), which entail complement truth values under only one matrix polarity, but generate strong pragmatic implicatures in the two-way implicative pattern under the non-entailing polarity.
Instruments to measure patient satisfaction with comprehensive medication management (CMM) services: a scoping review
Authors: Resende Lorayne Caroline , Michel Barbosa Mariana , Rezende Cristiane de Paula , Pantuza Laís Lessa Neiva , Reis Edna Afonso , Nascimento Mariana Martins Gonzaga 
Published: October 2023

Abstract

Objectives
To map the instruments to measure patient satisfaction with comprehensive medication management (CMM) services and to compare them according to their development characteristics and applicability of patient-reported outcome measures (PRO) measures.

Methods
A scoping review was conducted using the methodology proposed by the Joanna Briggs Institute and the PRISMA Extension for Scoping Reviews (PRISMA-ScR). Studies that developed or applied a patient satisfaction measurement instrument in CMM services, published from 1990 onwards were selected. The critical appraisal of the instruments identified was carried out using an 18 item checklist developed to systematically evaluate PRO measures.

Key findings
A total of 28 studies were selected; in most (17), the applied instruments had been developed by the authors. Nine of them were validated, most of which used open-ended and closed questions in self-administered printed instruments. The best-qualified instrument reached 11 out of the 18 evaluated items, highlighting the difficulty in the definition of the satisfaction construct.

Conclusions
The review made it possible to identify the instruments available to measure patient satisfaction with CMM services and to comparatively highlight their characteristics and psychometric properties. It also pointed out the need to improve or develop a patient satisfaction instrument for CMM services. However, improvement is needed in many of the evaluated domains of the instruments to meet the desirable requirements for a PRO measure. These gaps should be taken into consideration in future research, aiming to build a robust and standardized instrument for the CMM service.
Refugee Journalism in Indonesia: Self-Representation, Resistance, and Writing across Borders
Authors: Missbach Antje , Joniad J N , Adiputera Yunizar 
Published: October 2023

Abstract
By presenting the political engagements of a young refugee from Myanmar who was stuck in Indonesia for nine years, this article discusses the role, value, and importance of refugee writing. Refugees are prohibited from working in Indonesia. Any form of income-generation can result in serious pitfalls, including detention and other punishments. Writing—for international newspapers, blogs, and journals—presents a unique opportunity for earning money while also providing a platform for voicing refugee concerns and engaging in activism beyond borders. Yet, politically motivated writing also comes with certain risks, i.e., exposing the refugee authors to authorities. While this collaboratively written account portrays the struggles and the small and big successes in gaining a voice and communicating across borders of one refugee activist, it remains cautious in prescribing writing as an effective tool for all refugees stuck in transit, thus acknowledging also their ongoing destitution and precarity.
Pelvic organ prolapse after delivery: effects on sexual function, quality of life, and psychological health
Authors: Li Jie , Zhao Xiaoling , Li Juanhua , Liu Yuanwen , Li Tiantian 
Published: October 2023

Abstract

Background
Living with pelvic organ prolapse (POP) after delivery negatively impacted women’s daily living and was detrimental to their psychological health.

Aim
The purpose of the present study was to explore the effects of POP after delivery on women’s sexual function, quality of life (QoL), and psychological health within the first year following delivery.

Methods
A cross-sectional study was conducted with 640 female participants at obstetric clinic in 2 hospitals in Shenzhen, China.

Outcomes
All women completed following questionnaires: short form of the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12) on sexual function, Pelvic Floor Distress Inventory-20 (PFDI-20) on well-being and QoL, Symptom Checklist-90-Revised (SCL-90-R) on psychological health, and International Consultation on Incontinence Questionnaire Short Form.

Results
Women with symptomatic POP (N = 250) had higher mean scores (P &lt; .05) than those without symptoms (N = 390) in PISQ-12, PFDI-20, and SCL-90-R domains. In the symptomatic POP group (N = 250), the sexually dysfunctional group (N = 137) had significantly higher mean scores (P &lt; .001) than the sexually functional group (N = 113) in PISQ-12, PFDI-20, and SCL-90-R domains. Women with POP duration ≥6 months (N = 132) had significantly higher mean scores (P &lt; .001) than women with POP duration &lt;6 months (N = 118) in PISQ-12, PFDI-20, and SCL-90-R domains. The multiple linear regression model of PISQ-12 showed that constipation history, regular pelvic floor muscle training, parity, and symptomatic POP were independently correlated with the questionnaire score (P &lt; .05).

Clinical Implications
The significantly pervasive nature of POP often leads to the neglect of a substantial percentage of sexual problems and related emotional suffering, emphasizing the critical importance of raising awareness about this issue among clinicians and the general public.

Strengths and Limitations
The current study brought attention to significant aspects of postpartum POP; the findings suggest issues concerning POP occurrences and their impacts on sexual function, QoL, and psychological health. Primary constraints are linked to the utilization of self-report assessments.

Conclusion
The current study reveals a robust correlation between POP in postpartum women and compromised sexual function, QoL, and psychological health.
Uncertainty-based knowing how logic
Authors: Areces Carlos , Fervari Raul , Saravia Andrés R , Velázquez-Quesada Fernando R 
Published: October 2023

Abstract
We introduce a novel semantics for a multi-agent epistemic operator of knowing how, based on an indistinguishability relation between plans. Our proposal is, arguably, closer to the standard presentation of knowing that modalities in classical epistemic logic. We study the relationship between this new semantics and previous approaches, showing that our setting is general enough to capture them. We also study the logical properties of the new semantics. First, we define a sound and complete axiomatization. Second, we define a suitable notion of bisimulation and prove correspondence theorems. Finally, we investigate the computational complexity of the model checking and satisfiability problems for the new logic.
Probable low-frequency quasi-periodic oscillations in blazars from the ZTF survey
Authors: Banerjee Anuvab , Negi Vibhore , Joshi Ravi , Kumar Nagendra , Wiita Paul J , Chand Hum , Rawat Nikita , Wu Xue-Bing , Ho Luis C 
Published: October 2023

ABSTRACT
We investigate the possible presence of quasi-periodic oscillation (QPO) signals in 2103 blazars from the Zwicky Transient Facility (ZTF) time-domain survey. We detect a low-frequency QPO signal in five blazars observed over these 3.8-yr-long optical r-band ZTF light curves. These periods range from 144 to 196 d detected at ≳4σ significance levels in both the Lomb–Scargle periodogram and weighted wavelet Z-transform analyses. We find consistent results using the phase dispersion minimization technique. A similar peak is detected in the g-band light curves at a slightly lower significance of 3σ. Such nearly periodic signals on these time-scales in optical wavebands most likely originate from a precessing jet with high Lorentz factor, closely aligned to the observer’s line of sight or the movement of plasma blobs along a helical structure in the jet.
Phase shift between joint rotation and actuation reflects dominant forces and predicts muscle activation patterns
Authors: Sutton G P , Szczecinski N S , Quinn R D , Chiel H J 
Published: October 2023

Abstract
During behavior, the work done by actuators on the body can be resisted by the body's inertia, elastic forces, gravity, or viscosity. The dominant forces that resist actuation have major consequences on the control of that behavior. In the literature, features and actuation of locomotion, for example, have been successfully predicted by nondimensional numbers (e.g. Froude number and Reynolds number) that generally express the ratio between two of these forces (gravitational, inertial, elastic, and viscous). However, animals of different sizes or motions at different speeds may not share the same dominant forces within a behavior, making ratios of just two of these forces less useful. Thus, for a broad comparison of behavior across many orders of magnitude of limb length and cycle period, a dimensionless number that includes gravitational, inertial, elastic, and viscous forces is needed. This study proposes a nondimensional number that relates these four forces: the phase shift (ϕ) between the displacement of the limb and the actuator force that moves it. Using allometric scaling laws, ϕ for terrestrial walking is expressed as a function of the limb length and the cycle period at which the limb steps. Scale-dependent values of ϕ are used to explain and predict the electromyographic (EMG) patterns employed by different animals as they walk.
Ribosomal dysregulation: A conserved pathophysiological mechanism in human depression and mouse chronic stress
Authors: Zhang Xiaolu , Eladawi Mahmoud Ali , Ryan William George , Fan Xiaoming , Prevoznik Stephen , Devale Trupti , Ramnani Barkha , Malathi Krishnamurthy , Sibille Etienne , Mccullumsmith Robert , Tomoda Toshifumi , Shukla Rammohan 
Published: October 2023

Abstract
The underlying biological mechanisms that contribute to the heterogeneity of major depressive disorder (MDD) presentation remain poorly understood, highlighting the need for a conceptual framework that can explain this variability and bridge the gap between animal models and clinical endpoints. Here, we hypothesize that comparative analysis of molecular data from different experimental systems of chronic stress, and MDD has the potential to provide insight into these mechanisms and address this gap. Thus, we compared transcriptomic profiles of brain tissue from postmortem MDD subjects and from mice exposed to chronic variable stress (CVS) to identify orthologous genes. Ribosomal protein genes (RPGs) were down-regulated, and associated ribosomal protein (RP) pseudogenes were up-regulated in both conditions. A seeded gene co-expression analysis using altered RPGs common between the MDD and CVS groups revealed that down-regulated RPGs homeostatically regulated the synaptic changes in both groups through a RP-pseudogene-driven mechanism. In vitro analysis demonstrated that the RPG dysregulation was a glucocorticoid-driven endocrine response to stress. In silico analysis further demonstrated that the dysregulation was reversed during remission from MDD and selectively responded to ketamine but not to imipramine. This study provides the first evidence that ribosomal dysregulation during stress is a conserved phenotype in human MDD and chronic stress-exposed mouse. Our results establish a foundation for the hypothesis that stress-induced alterations in RPGs and, consequently, ribosomes contribute to the synaptic dysregulation underlying MDD and chronic stress-related mood disorders. We discuss the role of ribosomal heterogeneity in the variable presentations of depression and other mood disorders.
Feasibility of Low-Load Resistance Training Using Blood Flow Restriction for People With Advanced Multiple Sclerosis: A Prospective Cohort Study
Authors: Mañago Mark M , Cohen Evan T , Alvarez Enrique , Hager Emily R , Owens Johnny G , Bade Michael 
Published: October 2023

Abstract

Objective
The objective of this study was to determine the feasibility of low-load resistance training with blood flow restriction (BFR) for people with advanced disability due to multiple sclerosis (MS).

Methods
In this prospective cohort study, 14 participants with MS (Expanded Disability Status Scale [EDSS] score = 6.0 to 7.0; mean age = 55.4 [SD = 6.2] years; 71% women) were asked to perform 3 lower extremity resistance exercises (leg press, calf press, and hip abduction) bilaterally twice weekly for 8 weeks using BFR. Feasibility criteria were as follows: enrollment of 20 participants, ≥80% retention and adherence, ≥90% satisfaction, and no serious adverse events related to the intervention. Other outcomes included knee extensor, ankle plantar flexor, and hip abductor muscle strength, 30-Second Sit-to-Stand Test, Berg Balance Scale, Timed 25-Foot Walk Test, 12-Item MS Walking Scale, Modified Fatigue Impact Scale, Patient-Specific Functional Scale, and daily step count.

Results
Sixteen participants consented, and 14 completed the intervention, with 93% adherence overall. All participants were satisfied with the intervention. A minor hip muscle strain was the only intervention-related adverse event. There were muscle strength improvements on the more-involved (16%–28%) and less-involved (12%–19%) sides. There were also changes in the 30-Second Sit-to-Stand Test (1.9 repetitions; 95% CI = 1.0 to 2.8), Berg Balance Scale (5.3 points; 95% CI = 3.2 to 7.4), Timed 25-Foot Walk Test (−3.3 seconds; 95% CI = −7.9 to 1.3), Modified Fatigue Impact Scale (−8.8 points; 95% CI = −16.5 to −1.1), 12-Item MS Walking Scale (−3.6 points; 95% CI = −11.5 to 4.4), Patient-Specific Functional Scale (2.9 points; 95% CI = 1.9 to 3.8), and daily step count (333 steps; 95% CI = −191 to 857).

Conclusion
Low-load resistance training using BFR in people with MS and EDSS scores of 6.0 to 7.0 appears feasible, and subsequent investigation into its efficacy is warranted.

Impact
Although efficacy data are needed, combining BFR with low-load resistance training may be a viable alternative for people who have MS and who do not tolerate conventional moderate- to high-intensity training because of more severe symptoms, such as fatigue and weakness.

Lay Summary
Low-load strength training with BFR was feasible in people who have advanced disability due to MS. Using BFR may provide an alternative for people with MS who do not tolerate higher intensity training due to more severe symptoms, such as fatigue and weakness.