bluuebunny/crossref_metadata_2025_split huggingface dataset:
Attenuation of hepatitis A antibody after immunization with hepatitis A vaccine (Aimmugen) in people living with HIV
Authors: Koga Michiko , Saito Makoto , Kubota Megumi , Senkoji Tomoe , Adachi Eisuke , Ikeuchi Kazuhiko , Kikuchi Tadashi , Otani Amato , Takahashi Kazuaki , Tsutsumi Takeya , Yotsuyanagi Hiroshi 
Published: January 2024

AbstractAimHepatitis A (HA) is a vaccine‐preventable disease. In regions with good sanitation, men who have sex with men (MSM) are the key affected populations. During the 2018–2019 HA outbreak among MSM in Japan, we actively vaccinated MSM living with HIV (MSM‐LWHIV) with Aimmugen. As previously reported, their antibody seroconversion rate due to vaccination was lower than that of healthy individuals. However, the durability of Aimmugen in people living with HIV has not yet been reported. We evaluated attenuation after the one‐series vaccination (comprising three inoculations) and the factors associated with attenuation.MethodsWe retrospectively examined anti‐HA immunoglobulin G (anti‐HA‐IgG) titers and other clinical data from our hospital's medical records. Patients with no history of vaccination or HA infection (i.e., negative HA‐IgG titers) who received one series of Aimmugen, achieved seropositivity, and anti‐HA‐IgG antibodies were tested ≥2 years after three doses were included. Fisher’s exact test and the Mann–Whitney U‐test were performed. p < 0.05 was considered statistically significant.ResultsFifty‐one MSM‐LWHIV were included. All were seropositive after the third dose with a median HA‐IgG titer of 10.1 (interquartile range, 7.2–12.2) (sample/cut‐off values [s/co]). In 45 (40–49) months, seropositivity decreased to 90% (46/51) and was attenuated to a median of 4.4 (2.3–6.5) s/co. Lower baseline B cell counts (p = 0.049), lower anti‐HA‐IgG levels after the second dose (p = 0.002), and lower anti‐HA‐IgG levels after the third dose (p = 0.003) were associated with seronegativity.ConclusionsAnti‐HA‐IgG titers of vaccinated MSM‐LWHIV may be attenuated; thus, additional immunizations should be considered.
International migration and the NGOs working in the field of migration in Turkey
Authors: Özçetin Burak , Emre Perrin Öğün 
Published: January 2024

AbstractThis study aims to analyse the activities and discourses of the non‐governmental organizations (NGOs) working in the field of migration in Turkey. The research explores how the NGOs frame the issue of migration differently and how they define and comprehend migration, migrants, and refugees. The article discusses whether the NGOs view refugees as subjects needing help, support, and protection or as actors who have rights and must be empowered and argues that there is tension between the two approaches. These points are discussed through a field study, conducted in 2020 (between February and April), comprising in‐depth interviews with representatives of 13 NGOs working in the field of migration. The study points to structural, historical, and conjectural causes and aspects of the weakness of rights‐based attitudes and activities among the NGOs working in the field of migration in Turkey. The article finds out that the actions of the NGOs working in the field of migration are concentrated on the basic needs of refugees, and structural limitations, such as political pressure, political polarization, and capacity problems, push the NGOs to evaluate the issue of migration within relatively narrow frames. The article also stresses the importance of an enabling political and legal environment and a coherent and structured communication strategy to promote a rights‐based migration agenda.
Bacillus thuringiensis strains to control Noctuidae pests
Authors: Nascimento Tatiane Aparecida , de Carvalho Karine Silva , Martins Denize Carvalho , de Oliveira Cleidiane Rodrigues , de Carvalho Queiroz Margareth Maria , Valicente Fernando Hercos 
Published: January 2024

AbstractThis study aimed to select and characterize Bacillus thuringiensis strains with toxic activity on Helicoverpa armigera, Spodoptera cosmioides and Spodoptera eridania. Fifty B. thuringiensis (Bt) strains were used in selective bioassays for high mortality on H. armigera, and the four most efficient strains were tested on S. cosmioides and S. eridania. Twelve Bt strains were characterized by PCR to detect some cry, cyt and vip genes. Bioassays were also performed to detect the production of β‐exotoxins. Strain 237 caused a mortality rate of 95.6% due to β‐exotoxins. Strains 1368, 1521, 1814 and 3299 showed toxic activity on S. eridania. However, no strain was effective on S. cosmioides. The presence of β‐exotoxin was detected only in strain 237. The molecular characterization of the strains using specific cry, cyt and vip primers showed a great genetic diversity among the 12 strains that showed some mortality on H. armigera and S. eridania. Our results showed that detecting β‐exotoxin in Bt strains is important as it is toxic to insects and vertebrates and persistent in the environment. Strains 1368, 1521, 1814 and 3299 did not show toxicity to H. armigera, while they were toxic to S. eridania and did not produce β‐exotoxin. These strains may be useful for new formulations of biopesticides as well as for cloning and expression of plants' genes.
Does the superfluous killing exhibited by spiders mask the functional response parameters? A case study from the perspective of biological control
Authors: López‐Mercadal Júlia , Benhadi‐Marín Jacinto , Rodrigues Isabel , Miranda Miguel Ángel , Pereira José Alberto 
Published: January 2024

AbstractThe meadow spittlebug Philaenus spumarius L. (Hemiptera: Aphrophoridae) is a xylem‐sap feeder and the most abundant and widespread vector of Xylella fastidiosa (Xanthomonadales: Xanthomonadaceae) throughout Europe. Control strategies for the disease are based on containment and eradication measures regulated by the European Union. Within the context of biological control, the use of natural enemies aims at limiting the insect vector population in agroecosystems. Spiders are generalist predators with potential as biological control agents occupying all the habitats within crops. Crab spiders (Thomisidae) could be potential natural enemies against P. spumarius. The functional response (FR) of a predator represents the intake rate as a function of food availability and allows estimating feeding behaviour parameters such as the prey handling time and attack rate. However, spiders often kill more prey than they consume, unveiling their capacity as natural enemies. We assessed and compared the FR of Xysticus acerbus (Thomisidae) fed on P. spumarius in the laboratory considering (1) the total number of dead individuals and (2) only the consumed ones. We found that although both FRs were of type‐II, they significantly differed. The values of attack rate and handling time for consumed were 0.1 and 3.6, respectively, while for dead, the attack rate was 0.3 and 1.1, being both significantly different. Moreover, the number of overkilled individuals reached a plateau at the highest prey densities. Xysticus acerbus could be a potential natural enemy of P. spumarius. Nevertheless, we suggest that the effect of including the killed but not consumed prey individuals in FR studies using wasteful killing predators should be considered and further studied.
Survey on the implementation status and reproductive outcomes of oocyte and ovarian tissue cryopreservation in Japan: Historical comparison with nationwide surveys
Authors: Takae Seido , Harada Miyuki , Nakamura Kentaro , Furuyama Sayako , Ono Masanori , Osuga Yutaka , Suzuki Nao 
Published: January 2024

AbstractPurposeTo clarify the reproductive outcomes of fertility preservation (FP) treatment.MethodsWe conducted a mailed‐in questionnaire survey at institutions certified by the Japan Society of Obstetrics and Gynecology to investigate the number of oocyte cryopreservations (OC) and ovarian tissue cryopreservations (OTC) performed from December 2016 to the end of 2020. And, we conducted a detailed investigation of cases in which frozen specimens were used during the investigation period, and made historical comparisons with previous nationwide studies.ResultsResponses were received from 114 out of 150 facilities (response rate: 76.0%) for OC and 43 out of 51 for OTC (response rate: 84.3%). Breast cancer was the most common disease among patients whose FP specimens were used. During the study period, 1237 OCs and 198 OTCs were performed. In addition, 57 cycles of embryo transfer (ET) using cryopreserved oocytes and 12 cases of ovarian tissue transplantation (OTT) were performed. The mean age of patients who underwent ET using cryopreserved oocytes was 34.8 (±5.8) years, with a median age of 36 years. The pregnancy rate per ET using cryopreserved oocytes was 26.3% and the live birth rate (LBR) was 17.5%. Further, the LBR per patient was 43.3%, and the pregnancy rate following OTTs was 33.3%. Also, controlled ovarian stimulation using the random start method or the combination of aromatase inhibitors had no effect on pregnancy outcome.ConclusionImplementation of both OCs and OTCs have markedly increased over time in Japan, with comparable reproductive outcomes as other reports.
How Companies Restrain Means–Ends Decoupling: A Comparative Case Study of CSR Implementation
Authors: Athanasopoulou Andromachi , Marti Emilio , Risi David , Schlindwein Eva 
Published: January 2024

AbstractWe use the concept of means–ends decoupling to examine why companies continue to be major contributors to environmental and social problems despite committing increasingly to corporate social responsibility (CSR). Specifically, we ask: How do companies restrain (versus fail to restrain) means–ends decoupling? We answer this question through a comparative case study of four multinational companies with different levels of means–ends decoupling. Based on interviews and secondary data, we inductively identify two distinct approaches to CSR implementation: experimental vs. consistency‐oriented CSR implementation. Experimental CSR implementation means that companies (1) produce CSR knowledge about what is happening in specific CSR contexts and use this knowledge to (2) adapt CSR practices to local circumstances – an interplay that restrains means–ends decoupling. Consistency‐oriented CSR implementation lacks this interplay between knowledge production and practice adaptation, which fosters means–ends decoupling. Our model of experimental versus consistency‐oriented CSR implementation advances two streams of research. First, we advance research on means–ends decoupling by highlighting the importance of experimentation for restraining means–ends decoupling. Second, we advance research on the impact of CSR activities by questioning the widespread assumption that consistency should be at the heart of CSR implementation.
When organizational dehumanization hits home: Short‐scale validation and test of a spillover–crossover model
Authors: Lagios Constantin , Stinglhamber Florence , Restubog Simon Lloyd D. , Lagios Nicolas , Brison Noémie , Caesens Gaëtane 
Published: January 2024

AbstractOrganizational dehumanization, a concept that has garnered increasing scholarly attention, still faces two significant limitations within the current literature. First, there is a lack of rigorously validated scales in the field. Second, the effects of organizational dehumanization on the family domain have been largely overlooked. In light of these gaps, we embarked on a comprehensive research project comprising five studies (NTotal = 2635) to address these limitations. Our primary objectives were twofold: (1) to develop and validate a concise five‐item scale for measuring organizational dehumanization based on Caesens et al.'s (Eur. J. Work Org. Psychol., 26, 2017, 527‐540) 11‐item measure (Studies 1, 2 and 3) and (2) to investigate a novel spillover–crossover model of organizational dehumanization (Studies 4 and 5). Our results indicated that our proposed short scale has a good factorial structure and high reliability indices, correlates strongly with the 11‐item full scale, is invariant over time and demonstrates evidence for convergent, discriminant and incremental validity. In addition, using data from both employees and their family members, we showed that organizational dehumanization contributes to an increase in work‐to‐family conflict among employees, as perceived by their family members. This, in turn, heightens relationship tension within their family members, ultimately leading to a decline in their relationship satisfaction. Theoretical and practical implications and avenues for future research are also discussed.
Describing High School Stakeholders' Preferences for a Return‐to‐School Framework Following Concussion
Authors: Shepherd Heather A. , Heming Emily , Reed Nick , Caron Jeffrey G. , Yeates Keith O. , Emery Carolyn A. 
Published: January 2024

ABSTRACTBackgroundReturn to school supports are recommended to facilitate adolescents' re‐entry to school following a concussion. However, little is known as to what school stakeholders prefer for a return‐to‐school process. This study sought to describe the preferences of high school students, parents, and educators for a Return‐to‐School Framework for adolescents following a concussion.MethodsWe conducted qualitative semi‐structured, 1‐on‐1 or group interviews with high school students (n = 6), parents (n = 5), and educators (n = 15) from Calgary, Canada. Interviews aimed to describe participants' preferences for a Return‐to‐School Framework for students following a concussion. Interviews were analyzed using conventional content analysis.ResultsWe organized the data into 4 main themes: (1) purpose of the Return‐to‐School Framework; (2) format and operation of the Return‐to‐School Framework; (3) communication about a student's concussion; and (4) necessity of concussion education for students and educators.Implications for School Health Policy, Practice, and EquityA Return‐to‐School Framework following concussion should be developed in consultation with families, educators, and students and supports should be tailored to each student.ConclusionsParticipants preferred a standardized and consistent Return‐to‐School Framework including ongoing communication between stakeholders as well as feasible and individualized school supports.
‘To loosen up and talk’: Patients´ and facilitators´ experiences of discovery group sessions from the Tidal Model as an introduction before engaging in a person‐centred group intervention
Authors: Benzon Anne , Jørgensen Rikke 
Published: January 2024

Accessible SummaryWhat is known about the subject

Treatment groups in Mental Health Service is cost‐effective, increases patients´ self‐understanding and stimulate change

Research shows that people with mental illness have different barriers to attend group sessions which often originates from a lack of trust in other people, but it is known that the possibility to build gradual trust among the participants encourages attendance.

What the paper adds to existing knowledge

This study is based on the experience from outpatients and illuminates how discovery groups from the Tidal Model can be used as introductory sessions to build gradual trust among people with mental illness before engaging in a person‐centred group intervention.

The study fills a research gap in methods to create a safe and trusting environment in treatment groups for people with mental illness working with recovery‐oriented person‐centred interventions.

What are the implications for practice

This study emphasizes the importance of meeting concerns about social interactions in persons with mental illness when joining treatment groups. It presents a recovery‐oriented method which meets this requirement and is easy to implement in practice.

AbstractIntroductionRecovery‐oriented interventions delivered individually or in groups are more and more common within mental health nursing. However, persons with mental illness may be cautious about engaging in groups. Therefore, it is important to provide a trusting basis in the group to allow for the best opportunities to promote engagement, attendance and impact of treatment.AimThe aim was to explore how discovery group sessions were experienced as introductory sessions from the perspectives of participants and facilitators before engaging in a person‐centred group intervention.MethodA qualitative interview study was conducted, involving four group facilitators and 16 participants with mental illness from five completed groups. Data were analysed with Ricoeur's theory of interpretation.ResultsThe findings showed that the two discovery group sessions were experienced as useful and meaningful to all and created a safe atmosphere and a trusted relationship among group participants and facilitators.DiscussionFeeling safe and sharing experiences and emotions contribute to the relational climate in a group.Implication for practiceAddressing concerns about social interactions in persons with mental illness is important in group treatment. This study proved that engaging patients in designing or adapting interventions for mental health services is important to improve quality.
The ghost of past climate acting on present‐day plant diversity: Lessons from a climate‐based delimitation of the tropical alpine ecosystem
Authors: Kandziora Martha , Gorospe Juan M. , Salomon Luciana , Vásquez Diana L. A. , Vargas Maria Pinilla , Kolář Filip , Sklenář Petr , Schmickl Roswitha 
Published: January 2024

AbstractHabitat stability is important for maintaining biodiversity by preventing species extinction, but this stability is being challenged by climate change. The tropical alpine ecosystem is currently one of the ecosystems most threatened by global warming, and the flora close to the permanent snow line is at high risk of extinction. The tropical alpine ecosystem, found in South and Central America, Malesia and Papuasia, Africa, and Hawaii, is of relatively young evolutionary age, and it has been exposed to changing climates since its origin, particularly during the Pleistocene. Estimating habitat loss and gain between the Last Glacial Maximum (LGM) and the present allows us to relate current biodiversity to past changes in climate and habitat stability. In order to do so, (i) we developed a unifying climate‐based delimitation of tropical alpine regions across continents, and (ii) we used this delimitation to assess the degree of habitat stability, that is, the overlap of suitable areas between the LGM and the present, in different tropical alpine regions. Finally, we discuss the link between habitat stability and tropical alpine plant diversity. Our climate‐based delimitation approach can be easily applied to other ecosystems using our developed code, facilitating macro‐comparative studies of habitat dynamics through time.
Association between idiopathic hypersomnia and a genetic variant in the PER3 gene
Authors: Cherasse Yoan , Taira Yuki , Rassu Anna Laura , Barateau Lucie , Evangelista Elisa , Muratani Masafumi , Funato Hiromasa , Yanagisawa Masashi , Dauvilliers Yves 
Published: January 2024

SummaryWe aim to identify genetic markers associated with idiopathic hypersomnia, a disabling orphan central nervous system disorder of hypersomnolence that is still poorly understood. In our study, DNA was extracted from 79 unrelated patients diagnosed with idiopathic hypersomnia with long sleep time at the National Reference Center for Narcolepsy‐France according to very stringent diagnostic criteria. Whole exome sequencing on the first 30 patients with idiopathic hypersomnia (25 females and 5 males) allowed the single nucleotide variants to be compared with a control population of 574 healthy subjects from the French Exome project database. We focused on the identification of genetic variants among 182 genes related to the regulation of sleep and circadian rhythm. Candidate variants obtained by exome sequencing analysis were then validated in a second sample of 49 patients with idiopathic hypersomnia (37 females and 12 males). Our study characterised seven variants from six genes significantly associated with idiopathic hypersomnia compared with controls. A targeted sequencing analysis of these seven variants on 49 other patients with idiopathic hypersomnia confirmed the relative over‐representation of the A➔C variant of rs2859390, located in a potential splicing‐site of PER3 gene. Our findings support a genetic predisposition and identify pathways involved in the pathogeny of idiopathic hypersomnia. A variant of the PER3 gene may predispose to idiopathic hypersomnia with long sleep time.
OsBCAT2, a gene responsible for the degradation of branched‐chain amino acids, positively regulates salt tolerance by promoting the synthesis of vitamin B5
Authors: Sun Yangyang , Zhou Yutong , Long Qiyuan , Xing Junwei , Guo Peizhen , Liu Yanchen , Zhang Changjian , Zhang Yuanyuan , Fernie Alisdair R. , Shi Yuheng , Luo Yuehua , Luo Jie , Jin Cheng 
Published: January 2024

Summary

Salt stress negatively affects rice growth, development and yield. Metabolic adjustments contribute to the adaptation of rice under salt stress. Branched‐chain amino acids (BCAA) are three essential amino acids that cannot be synthesized by humans or animals. However, little is known about the role of BCAA in response to salt stress in plants.

Here, we showed that BCAAs may function as scavengers of reactive oxygen species (ROS) to provide protection against damage caused by salinity. We determined that branched‐chain aminotransferase 2 (OsBCAT2), a protein responsible for the degradation of BCAA, positively regulates salt tolerance.

Salt significantly induces the expression of OsBCAT2 rather than BCAA synthesis genes, which indicated that salt mainly promotes BCAA degradation and not de novo synthesis. Metabolomics analysis revealed that vitamin B5 (VB5) biosynthesis pathway intermediates were higher in the OsBCAT2‐overexpressing plants but lower in osbcat2 mutants under salt stress. The salt stress‐sensitive phenotypes of the osbcat2 mutants are rescued by exogenous VB5, indicating that OsBCAT2 affects rice salt tolerance by regulating VB5 synthesis.

Our work provides new insights into the enzymes involved in BCAAs degradation and VB5 biosynthesis and sheds light on the molecular mechanism of BCAAs in response to salt stress.
The Transformative power of friendships: Examining the relationships among friendship quality, self‐change, and well‐being
Authors: Yücel Emine , Dincer Duygu 
Published: January 2024

AbstractFriendships are beneficial to a person's growth and well‐being. People in close relationships may experience four types of self‐change: self‐expansion, self‐pruning, self‐contraction, and self‐adulteration. The current cross‐sectional research sought to investigate whether these relational self‐change processes explain the links between friendship quality and well‐being in same‐sex best friendships. Study 1A (N = 187) adapted the Turkish Relational Self‐Change Scale to the friendship context and confirmed its psychometric adequacy in addressing friendship‐based self‐changes in Türkiye. Study 1B (N = 306) examined the links between different friendship functions and relational self‐changes, as well as whether relational self‐changes explain the link between friendship quality and ontological well‐being. Among the specific friendship functions, stimulating companionship and self‐validation were related to self‐expansion and self‐pruning, whereas reliable alliance was related to self‐contraction and self‐adulteration. Self‐adulteration also indirectly explained the relationship between friendship quality and ontological well‐being. Study 2 (N = 204) revealed that only self‐pruning explained the link between perceived friend responsiveness and overall well‐being. The contributions of friendships to self‐change and personal well‐being were discussed in light of the findings.