bluuebunny/crossref_metadata_2025_split huggingface dataset:
Age-associated mortality is partially mediated by TERT promoter mutation status in differentiated thyroid carcinoma
Authors: Heo Jung , Lee Sungjoo , Park Jun , Yang Heera , Park Hyunju , Ki Chang-Seok , Oh Young Lyun , Kim Hye In , Kim Sun Wook , Chung Jae Hoon , Kim Kyunga , Kim Tae Hyuk 
Published: November 2023

Background
Age at diagnosis (AAD) and telomerase reverse transcriptase (TERT) promoter mutations are prognostic factors in differentiated thyroid carcinoma (DTC), and the prevalence of the mutations increases with AAD. Considering this correlation, we investigated whether an interaction between AAD and the mutations is present and whether the mutation mediates the effect of AAD on the mortality rate in DTC.

Methods
The study included 393 patients with DTC who were followed-up after thyroidectomy at a single medical center in Korea from 1994 to 2004. Multivariable Cox regression was used to investigate the interaction of AAD and TERT promoter mutation. Mediation analysis was conducted using a regression-based causal mediation model.

Results
The age-associated mortality rate increased progressively in all DTC patients and wild-type TERT group (WT-TERT) with a linear trend (p < 0.001) contrary to mutant TERT group (M-TERT) (p = 0.301). Kaplan-Meier curves declined progressively with increasing AAD in the entire group, but the change was without significance in M-TERT. The effect of AAD on mortality was not significant (adjusted HR: 1.07, 95% CI 0.38–3.05) in M-TERT. An interaction between AAD and TERT promoter mutation (p = 0.005) was found in a multivariable Cox regression. TERT promoter mutations mediated the effect of AAD on the mortality rate by 36% in DTC in a mediation analysis.

Conclusions
Considering the mediation of TERT promoter mutation on the effect of AAD on mortality, inclusion of TERT promoter mutation in a stage classification to achieve further individualized prediction in DTC is necessary.
Tribocorrosion in biomaterials and control techniques: a review
Authors: Puthillam Umanath , Selvam Renold Elsen 
Published: November 2023

Abstract
Tribocorrosion is getting more and more popular in biomaterials research. The synergism between wear and corrosion is creating deviations from the expected real-world results from individual corrosion or wear studies. The host body consisting of immune system and dissolved proteins makes them highly corrosive which makes the material selection a unique and challenging process for implant materials. The synergism between corrosion and wear leads to shorter implant life. The research on tribocorrosion has bought an insight into this phenomenon and presented ideas to arrest the premature failure of implants. This review focuses on the recent developments in tribocorrosion research and the effectiveness of remedial actions suggested by them. The influence of materials, processing methods and post-processing treatments are also reviewed in detail.
Cation-doping effects on the conductivities of the mayenite Ca12Al14O33
Authors: Song Xingping , Guo Yaqiong , Chen Wenzhuo , Hou Keke , Duan Xiaoxu , Xu Jungu 
Published: November 2023

Abstract
The mayenite Ca12Al14O33 material, owing to its oxide ion conducting behavior and the low cost of raw materials, has the potential of being applied in solid oxide fuel cells as an electrolyte. However, suffering from the relatively low oxide ion conductivity, there is still a long way to go for its practical application. To enhance the oxide ion conduction in Ca12Al14O33, many efforts have been endowed to this from different research groups but hardly succeeded. In this work, the Ca12Al14O33-based materials with Y, In, and Cu-doping on the Ca or Al sites were fabricated through a traditional solid-state reaction method (for Y-doping on Ca and Cu-doping on Al) or a glass-crystallization method (for In-doping on Al), with their electrical conductivities being studied. The results revealed that the solid solution regions of Ca12−x
Y
x
Al14O33+δ
, Ca12Al14−x
In
x
O33, and Ca12Al14−x
Cu
x
O33−δ
were 0 ≤ x ≤ 0.15, 0 ≤ x ≤ 0.1, and 0 ≤ x ≤ 0.3, respectively. The electrical conductivities of all these doped materials were investigated.
“God Has Commanded Me”: A Spiritual Code of a Traditional Birth Attendance (TBA)
Authors: Zaluchu Sonny , Zaluchu Fotarisman 
Published: November 2023

Abstract
Many studies have demonstrated the significant involvement of Traditional Birth Attendants (TBAs) during pregnancy and delivery. In several countries, including Indonesia, the role of the TBA cannot be easily replaced by Skilled Birth Attendants (SBAs), reducing the capacity of the health sector to reduce the maternal mortality rate. The TBA has a religious and social connection with the community in her area which is often undervalued by the medically-trained SBA; this disconnect interferes with the provision of quality care. In this paper, with the use of a narrative approach, a TBA reveals her reflection and perspective as rooted in the community where she lives. This ethnography provides living evidence that the point of view of modern health professionals often fails when faced with the world view of the community. TBAs have social power that cannot be separated from the social context where they live. Therefore, an analysis of the religious aspects of a TBA’s practice should enrich the effort to decrease the maternal mortality rate. The religiosity of a community is closely connected with the community’s perspective on health.
A Pilgrim’s Performance: Practical Theology as Convening
Authors: Benac Dustin D. 
Published: November 2023

Abstract
Convening is a mode of practical theology inquiry that stages a counter-performance to the spectacle of prominent logics that order ecclesial life: brand Christianity, silos, and competition. Three parts organize this argument: Part I sets the stage with a preliminary portrait of convening, noting the contextual features of this inquiry. Part II introduces Augustine’s City of God as an interpretive lens to understand convening as a counter-performance to prominent spectacles on display. Part III redescribes convening by combining Augustine’s theological vision of spectacle, performance, latreia, and pilgrimage with the introductory portrait in order to perform what is possible when people of faith gather for collective inquiry.
A New-Old Spirituality: How Spirituality has Softened and Revitalized Religion
Authors: Kaufman Tone Stangeland 
Published: November 2023

Abstract
This article seeks to continue the unfolding of the tangled relationship of spirituality and religion but from the vantage point of Christianity (religion), and more specifically, from Christian practice and from the perspective of representatives of institutionalized religion (clergy) and rather unchurched participants in organized religious practice. While first-wave scholars argued that religion and spirituality are at odds with each other, second-wave scholars rather consider the relationship between the two more blurred and hybrid. Following the lead of this latter group of scholarship, I make the case that contemporary spirituality at the intersection of “individualized spirituality” and “institutionalized religion” can be understood as a new-old spirituality and that religion is being changed by spirituality. This entails that people are approaching old Christian practices in new ways and new places often urged by a new kind of motivation. By attending to issues of subjectivity and regarding experience as a significant source of authority without leaving the theistic framework of religion altogether, this new-old spirituality is available and attractive to constituencies as varied as clergy, children, incarcerated, and young people. Hence, it can be argued that religion is not only giving way to spirituality. Religion is also softened and revitalized by spirituality, as empirical studies in the Scandinavian countries show a resurgence and revitalization of religious practice, both inside and at the margins of institutionalized religion, and, thus, a sacralization of the congregational domain.
Die Qualifizierung zum „Wissenschaftlichen Dokumentar“ am Lehrinstitut für Dokumentation 1966 bis 1991 – berufsbegleitende Weiterbildung der DGD als Strukturmodell
Authors: Oßwald Achim 
Published: November 2023

Zusammenfassung
Die Konzeption und Entwicklung der Jahreslehrgänge für Wissenschaftliche Dokumentare am Lehrinstitut für Dokumentation (LID) der Deutschen Gesellschaft für Dokumentation (DGD) im Zeitraum 1966–1991 wird dargestellt und analysiert. Strukturelle und statistische Aspekte sowie die Bedeutung dieser Weiterbildung für den Dokumentationsbereich in Deutschland und als Strukturmodell für berufsbegleitende Weiterbildungen werden angesprochen.
Fault diagnosis of electrical equipment based on virtual simulation technology
Authors: Chang Jing , Li Huiqin , Xiao Na , Singh Pavitar Parkash , Vats Prashant , Reddy Chinthalacheruvu Venkata Krishna 
Published: November 2023

Abstract
In order to efficiently and accurately diagnose train electrical faults, we propose a fault diagnosis method for electrical equipment based on virtual simulation technology. First, Creo software was used to build a subway train model. Then, 3DMAX software was used to make animation and demonstrate the working principle and action process of the train electrical system. Finally, using Unity 3D software, a human–computer interaction mechanism was established, achieving presence and realism. This system realizes the functions of knowledge learning, student assessment, principal display, and troubleshooting of the electrical system of subway trains and is compared with the method of manual diagnosis. Experimental results show that in the designed fault diagnosis system, the detection time for various types of faults is shorter than 30 s, whereas the diagnosis time of the manual diagnosis method is 30–52 s. It shows that the electrical equipment fault diagnosis system based on virtual simulation has the advantages such as short fault diagnosis time and high efficiency. In addition, the highest diagnostic accuracy of the manual diagnosis method is 75.48%, which is far lower than the accuracy of the diagnostic system. Conclusion: It is proved that the designed fault diagnosis system has the advantages such as short detection time and high accuracy and can meet the safety requirements of industrial production.
Global patterns and temporal trends in ovarian cancer morbidity, mortality, and burden from 1990 to 2019
Authors: Mazidimoradi Afrooz , Momenimovahed Zohre , Khani Yousef , Rezaei Shahrabi Armin , Allahqoli Leila , Salehiniya Hamid 
Published: November 2023

Abstract

Objectives
Ovarian cancer (OC) is the deadliest gynecological cancer in the world. Deeper knowledge over time is the basis for global studies to design and implement effective measures to reduce inequalities; this study was conducted to investigate the trend of OC incidence and management in the world from 1990 to 2019.

Methods
We obtained crude numbers and age-standardized rate (ASRs) of OC annually from the 2019 Global Burden of Disease (GBD) study to examine OC’s morbidity, mortality rates, and disability-adjusted life years (DALYs) based on age group, sociodemographic index (SDI), WHO regions, continents, World Bank regions, and GBD regions from 1990 to 2019 in 204 countries and territories. The relative change (%) and average Annual Percent Change (AAPC) were used to display the epidemiological trend.

Results
Globally, the number of OC incidents increased from 141,706 in 1990 to 294,422 in 2019. Despite the age-standardized incidence rate (ASIR) in regions with high SDI having a downward trend, these areas recorded the highest incidence cases and ASIR in 2019. Although the World Bank high-income level had the most frequent incidence cases and ASIR, the ASIR in these regions decreased from 1990 to 2019. Among the continents, Europe and America have the highest ASIR but experienced a decreasing trend from 1990 until 2019 in ASIR. The age-standardized mortality rate (ASMR) in the World Bank high-income level experienced a decreasing trend in 1990–2019. In contrast, in the middle, low-middle, and low SDI regions, the death number increased approximately 3.5–4.1 times, and the ASMR had a significant increase from 0.5 in the middle to 0.75 in the low-middle SDI. Globally, the DALY cases of OC rose from 2,732,666 in 1990 to 5,359,737 in 2019; almost doubling. A significant decrease in the DALYs ASR was observed in seven GBD regions. The most pronounced decrease was found in Australia.

Conclusions
The trend of OC incidence and burden and approximate mortality were stable from 1990 to 2019; especially in lower socioeconomic areas and low-income countries; while the incidence ASR of this cancer in the high SDI regions decreased from 1990 to 2019. The key to reducing OC remains in primary prevention. Approaches such as weight loss, a healthy lifestyle and diet, promoting childbearing and breastfeeding, and recommending the use of oral contraceptives in eligible individuals can have a protective effect against this silent killer.
Integrative machine learning algorithms for developing a consensus RNA modification-based signature for guiding clinical decision-making in bladder cancer
Authors: Jia Shijun , Zhai Linhan , Wu Feng , Lv Wenzhi , Min Xiangde , Zhang Shuang , Li Feng 
Published: November 2023

Abstract

Objectives
Dysregulation of RNA modifications has emerged as a contributor to cancer, but the clinical implication of RNA modification-related genes remains largely unclear. The study focused on well-studied RNA modification modalities (m6A, m1A, m5C and m7G) in bladder cancer, and proposed a machine learning-based integrative approach for establishing a consensus RNA modification-based signature.

Methods
Multiple publicly available bladder cancer cohorts were enrolled. A novel RNA modification-based classification was proposed via consensus clustering analysis. RNA modification-related genes were subsequently selected through WGCNA. A machine learning-based integrative framework was implemented for constructing a consensus RNA modification-based signature.

Results
Most RNA modifiers were dysregulated in bladder tumours at the multi-omics levels. Two RNA modification clusters were identified, with diverse prognostic outcomes. A consensus RNA modification-based signature was established, which displayed stable and powerful efficacy in prognosis estimation. Notably, the signature was superior to conventional clinical indicators. High-risk tumours presented the activation of tumourigenic pathways, with the activation of metabolism pathways in low-risk tumours. The low-risk group was more sensitive to immune-checkpoint blockade, with the higher sensitivity of the high-risk group to cisplatin and paclitaxel. Genes in the signature: AKR1B1, ANXA1, CCNL2, OAS1, PTPN6, SPINK1 and TNFRSF14 were specially expressed in distinct T lymphocytes of bladder tumours at the single-cell level, potentially participating in T cell-mediated antitumour immunity. They were transcriptionally and post-transcriptionally modulated, and might become potentially actionable therapeutic targets.

Conclusions
Altogether, the consensus RNA modification-based signature may act as a reliable and hopeful tool for improving clinical decision-making for individual bladder cancer patients.
Hidden in plain sound: overlooked repetition in Just a Minute
Authors: Wray Alison 
Published: November 2023

Abstract
In the BBC Radio Four panel game Just a Minute (JaM), players must speak fluently for one minute without hesitation, deviation, or repetition. Other players challenge them and take over the remainder of the minute if successful. What impact do the JaM rules have on players’ spoken output? Study 1 compares twelve unchallenged JaM minutes with twelve sample minutes from an interview by the same speaker, Paul Merton. Although lower, his repetition rate in JaM is still >34%. Study 2 asks why so many repeated words go unchallenged. Analysis of 97 JaM rounds (18,500 words) from 12 complete episodes reveals that word class, word frequency, and the distance between mentions all play a role. The parameters of challenges in the game are modeled and there is consideration of why and how repetition occurs in a language and how the wider priorities of JaM as entertainment shape the linguistic patterns.
Las locuciones hiperbólicas
Authors: Martínez Inmaculada Penadés 
Published: November 2023

Abstract
In contrast to the case of metaphorical and metonymical idioms, there is no research specifically concerned with Spanish hyperbolic idioms. This article shows that it is possible to apply different definitions and characterizations of hyperbole to idioms that should be considered hyperbolic. The analysis is based on idiomaticity and is supported by the distinction between the literal and idiomatic meanings of these fixed expressions. In the conclusions, seven criteria are established to identify hyperbolic idioms, and the types are differentiated according to: 1) the conceptual mechanisms of metaphor and metonymy that explain their formation, 2) the form and meaning of their constituent parts, and 3) the semantic fields in which they are included. Finally, we point out the need to continue analyzing these types of idioms from both a theoretical and an applied perspective, in the latter case with a possible view to marking them as hyperbolic in dictionaries.
Zur Diachronie der Valenz von Verbphrasemen mit der Struktur Adjektiv + Kopula
Authors: Korhonen Jarmo 
Published: November 2023

Abstract
Some adjectives in the German language can only be used in connection with a copula verb (e. g., ansichtig werden and eingedenk sein/bleiben). Other adjectives can have different meanings, among which a particular meaning restricted to predicative use (i. a. bar sein). Since these constructions consist of an adjective and a fixed verb component, they can be classified as phrasemes or even as verb phrasemes. Verb phrasemes and one-word lexemes can demand a certain number of complements with a particular form and syntactic function and a certain meaning. The choice of the valency characteristics of phrasemes with a predicative adjective as the subject of this article is explained by the fact they have not yet been systematically analyzed concerning the diachronic perspective.
The research approach and method examine each phraseme in its valency occurrences, documenting these by examples found in historical and modern dictionaries as well as in corpora of different kinds from Old High German to Modern German. The valency occurrences consist of a combination of complements, which are recorded as so-called complete valency. Both the quantitative and qualitative variation of complements are contained in the complete valency and can therefore be called polyvalency. Quantitative polyvalency refers to the number of complements while qualitative polyvalency refers to the type of complements. Each combination of complements found in the research material is illustrated with an example. Finally, the quantitative and qualitative valency developments are summarized in a short commentary.
Molecular dynamics simulation on electrohydrodynamic atomization: Stable dripping mode by pre-load voltage
Authors: Bai Dongqiao , Huang Jin , Wang Jianjun , Jiang Shan , Gong Hongxiao , Liang Chaoyu 
Published: November 2023

Abstract
The electrohydrodynamic atomization (EHDA) process is a method of forming liquid droplets or jets in a solution under an electric field. Molecular dynamics simulations were used in this study to reveal the EHDA dripping mode at a microscopic level. In this study, we investigated whether a liquid contains ions under the influence of a 1 V·nm−1 electric field that affects the dipole direction of water molecules to explore the cause of the dripping mode. It was hypothesized that the presence of ions would disrupt the local electric field distribution, causing liquid rupture. Furthermore, we observed the jetting behavior under varying ion concentrations and identified jetting instability. To solve this problem, the pre-load voltage method was used to control the distribution of ions in the solution, thus effectively increasing the ion concentration at the nanotube opening. In this study, we also investigated the movement behavior of ions in solution under different pre-load voltages, leading to a stable dripping mode under different ion concentrations. This study offers microscale mechanism research perspectives for EHDA and can be used in future studies for parameter setting and optimization.
Unraveling the surface activity and micellization characteristics of linear alkyl benzene sulfonate in aqueous solution
Authors: Budhalakoti Bharti , Kothiyal Navin Chandra 
Published: November 2023

Abstract
The aggregation behavior of various neutralizing agents (monovalent and diamine bases) has been investigated for linear alkylbenzene sulfonate. Measurements employing conductivity at temperature (298.15 K, 303.15 K, 308.15 K, and 313.15 K) and surface tension at 298.15 K have been determined to study micellization and surface active properties. The conductivity versus concentration plot elucidated CMC and dissociation of counterion (α). Additionally, surface active parameters ϒCMC, A
min, π
CMC, and τ
max were investigated via tensiometry using the Wilhelmy plate procedure. The wettability characteristic of the surfactant solution was determined using contact angle analysis. Furthermore, the particle size parameters were determined using DLS measurements. The Gemini salts of LABS portrayed improved efficiency and demonstrated economical in domestic and industrial applications.
Evaluation of the Effects of Different Strain Paths on the Behavior of Sands Using Direct Simple Shear Tests
Authors: Tohidvand Hamid Reza , Hajialilue-Bonab Masoud , Katebi Hooshang 
Published: November 2023

Abstract
Many researchers have evaluated different parameters that can affect the mechanical behavior of sands. However, most of the conducted investigations considered drained and undrained stress–strain paths as the limiting boundaries of the behavior; recently applied studies have indicated that this assumption cannot be accurate for all situations. In this paper, by using expansive and contractive strain paths (in addition to the conventional constant volume path), partially drained responses of sands are simulated. Influences of different grain size distributions on the behavior of sands are studied by controlled coupling between volumetric to shear strain ratios. The results show that the asymptotic stress ratio (steady state stress ratio), phase transformation stress ratio, and instability stress ratio depend on the experienced strain paths and cannot be considered material constant (inherent) parameters. It is shown that coarse sands can be affected by the various strain paths more than finer sands, and loose sands are more sensitive against the partially drained strain paths compared to dense sands.