bluuebunny/crossref_metadata_2025_split huggingface dataset:
Climate trends and maize production nexus in Mississippi: empirical evidence from ARDL modelling
Authors: Sharma Ramandeep Kumar , Dhillon Jagmandeep , Kumar Pushp , Bheemanahalli Raju , Li Xiaofei , Cox Michael S. , Reddy Krishna N. 
Published: October 2023

AbstractClimate change poses a significant threat to agriculture. However, climatic trends and their impact on Mississippi (MS) maize (Zea maysL.) are unknown. The objectives were to: (i) analyze trends in climatic variables (1970 to 2020) using Mann–Kendall and Sen slope method, (ii) quantify the impact of climate change on maize yield in short and long run using the auto-regressive distributive lag (ARDL) model, and (iii) categorize the critical months for maize-climate link using Pearson’s correlation matrix. The climatic variables considered were maximum temperature (Tmax), minimum temperature (Tmin), diurnal temperature range (DTR), precipitation (PT), relative humidity (RH), and carbon emissions (CO2). The pre-analysis, post-analysis, and model robustness statistical tests were verified, and all conditions were met. A significant upward trend in Tmax (0.13 °C/decade), Tmin (0.27 °C/decade), and CO2(5.1 units/decade), and a downward trend in DTR ( − 0.15 °C/decade) were noted. The PT and RH insignificantly increased by 4.32 mm and 0.11% per decade, respectively. The ARDL model explained 76.6% of the total variations in maize yield. Notably, the maize yield had a negative correlation with Tmax for June, and July, with PT in August, and with DTR for June, July, and August, whereas a positive correlation was noted with Tmin in June, July, and August. Overall, a unit change in Tmax reduced the maize yield by 7.39% and 26.33%, and a unit change in PT reduced it by 0.65% and 2.69% in the short and long run, respectively. However, a unit change in Tmin, and CO2emissions increased maize yield by 20.68% and 0.63% in the long run with no short run effect. Overall, it is imperative to reassess the agronomic management strategies, developing and testing cultivars adaptable to the revealed climatic trend, with ability to withstand severe weather conditions in ensuring sustainable maize production.
Cells solved the Gibbs paradox by learning to contain entropic forces
Authors: Baker Josh E. 
Published: October 2023

AbstractAs Nature’s version of machine learning, evolution has solved many extraordinarily complex problems, none perhaps more remarkable than learning to harness an increase in chemical entropy (disorder) to generate directed chemical forces (order). Using muscle as a model system, here I describe the basic mechanism by which life creates order from disorder. In short, evolution tuned the physical properties of certain proteins to contain changes in chemical entropy. As it happens these are the “sensible” properties Gibbs postulated were needed to solve a paradox that has intrigued and challenged scientists and philosophers for over 100 years.
Molecular data storage using direct analysis in real time (DART) ionization mass spectrometry for decoding
Authors: Pardi-Tóth Veronika , Kuki Ákos , Kordován Marcell Árpád , Róth Gergő , Nagy Lajos , Zsuga Miklós , Nagy Tibor , Kéki Sándor 
Published: October 2023

AbstractMolecular data storage is becoming a viable alternative to traditional information storage systems. Here, we propose a method where the presence or absence of a given molecule in a mixture of compounds represents a bit of information. As a novel approach, direct analysis in real time (DART) ionization mass spectrometry is used to recover and decode the information stored at the molecular level. Nicotinic acid derivatives were synthesized and used as the ‘bit compounds’. Their volatility and ease of ionization make these molecules especially suitable for DART-MS detection. The application of DART-MS as a method with an ambient ionization technique, enables the re-reading of digital chemical codes embedded in the material of ordinary objects. Our method is designed to store and read back short pieces of digital information, up to several hundred bits. These codes can have the function of barcodes or QR codes, as shown in our proof-of-principle applications. First, modelling a QR code as a link to our university's website, three solutions were prepared, each representing 22 bits. Proceeding further, the bit compounds were incorporated into a polymer matrix that is suitable for 3D printing, and a toy ship was created with a hidden barcode. In addition, decoding software was developed to process the DART-MS spectra. The nicotinic acid components representing the bits dominated the DART-MS spectra and error-free decoding was achieved.
Utilising random forests in the modelling of Eragrostis curvula presence and absence in an Australian grassland system
Authors: Brown J. , Merchant A. , Ingram L. 
Published: October 2023

AbstractEragrostis curvula is an agronomically and ecologically undesirable perennial tussock grass dispersed across Australia. The objective of this study is to investigate relationships of ecologically relevant abiotic variables with the presence of E. curvula at a landscape scale in the Snowy Monaro region, Australia. Through vegetation surveys across 21 privately owned properties and freely available ancillary data on E. curvula presence, we used seven predictor variables, including Sentinel 2 NDVI reflectance, topography, distance from roads and watercourses and climate, to predict the presence or absence of E. curvula across its invaded range using a random forest (RF) algorithm. Assessment of performance metrics resulted in a pseudo-R squared of 0.96, a kappa of 0.97 and an R squared for out-of-bag samples of 0.67. Temperature had the largest influence on the model’s performance, followed by linear features such as highways and rivers. Highways’ high importance in the model may indicate that the presence or absence of E. curvula is related to the density of human transit, thus as a vector of E. curvula propagule dispersal. Further, humans’ tendency to reside adjacent to rivers may indicate that E. curvula’s presence or absence is related to human density and E. curvula’s potential to spread via water courses.
Identification of KIFC1 as an independent prognostic marker in renal clear cell carcinoma correlates with tumor proliferation and immune infiltration
Authors: Du Bin , Wang Jia , Zheng Jinping , Huo Jing , Wang Pu 
Published: October 2023

Abstract
Renal clear cell carcinoma (ccRCC) is the world's most common form of cancer. Up to a third will develop metastases; the 5-year survival rate of the patients was only 14%. Practical prognostic markers remain to be discovered. Kinesin-like protein (KIFC1), a critical factor in maintaining the stability of the microtubule system, has significant prognostic value in some tumors. We analyzed the prognostic value, associated signaling pathways, and regulatory mechanisms of KIFC1 in ccRCC through bioinformatics and proteomics. Concretely, both mRNA and protein expression levels of KIFC1 were dramatically upregulated. KIFC1 is an independent prognostic factor for ccRCC. The expression of KIFC1 showed a significant positive correlation (Spearman coefficient > 0.7) with tumor proliferation-related pathways (tumor proliferation, G2/M checkpoint, and DNA replication) and tumor inflammation. Further, intratumoral immune cell analysis revealed that high expression of KIFC1 predicted more infiltration of CD8 + T and CD4 + T cells (p < 0.001). However, there was a significant positive relationship between CD8 + T cells and numerous immune checkpoint genes. CD8 + T cells in tumors from the KIFC1 high expression group were at the dysregulated state. High expression of KIFC1 may predict a poor immunotherapy outcome. By proteomics, we analyzed proteins interacting with KIFC1; spliceosome proteins had the most significant enrichment, indicating the new directions for KIFC1 investigation. In conclusion, our study identified KIFC1 as an independent prognostic factor in renal clear cell carcinoma, and the associated processes involved tumor proliferation and immune infiltration. KIFC1 had a close relationship with spliceosome proteins; it may be a new research direction.
Highly efficient lead removal from water by Nd0.90Ho0.10FeO3 nanoparticles and studying their optical and magnetic properties
Authors: Arman M. M. 
Published: October 2023

AbstractHo-doped NdFeO3 was synthesized using the citrate method. The X-ray diffraction (XRD) illustrated that Nd0.90Ho0.10FeO3 was crystalline at the nanoscale, with a crystallite size of 39.136 nm. The field emission scanning electron microscope (FESEM) illustrated the porous nature of Nd0.90Ho0.10FeO3, which increases the active sites to absorb the heavy metals on the sample surface. Energy-dispersive X-ray (EDX) data assures the prepared sample has the chemical formula Nd0.90Ho0.10FeO3. The magnetic properties of Nd0.90Ho0.10FeO3 were determined using the magnetization hysteresis loop and Faraday’s method. Many magnetic parameters of the sample have been discussed, such as the coercive field, the exchange bias (Hex), and the switching field distribution (SFD). Ho-doped NdFeO3 has an antiferromagnetic (AFM) character with an effective magnetic moment of 3.903 B.M. The UV–visible light absorbance of Nd0.90Ho0.10FeO3 is due to the transfer of electrons from the oxygen 2p state to the iron 3d state. Nd0.90Ho0.10FeO3 nanoparticles have an optical direct transition with an energy gap Eg = 1.106 eV. Ho-doped NdFeO3 can adsorb many heavy metals (Co2+, Ni2+, Pb2+, Cr6+, and Cd2+) from water. The removal efficiency is high for Pb2+ ions, which equals 72.39%. The Langmuir isotherm mode is the best-fit model for adsorbing the Pb2+ ions from water.
On the creation of a photon by an electromagnetic wave ball
Authors: Light Gregory L. 
Published: October 2023

AbstractRecent literature has shown, theoretically as well as experimentally, that while a beam splitter does not split a single photon, it nonetheless divides the electromagnetic wave into transmitted and reflected, with both containing energies. This implies the existence of a spacetime of pure electromagnetic waves of energies but without particles; also, it prompts the question on how much energy a photon loses after coming out of a beam splitter, which impacts on interferometry and hence quantum communication. This paper shows that, by Gauss divergence theorem, the gravitational force inside an electromagnetic wave ball results in a point energy that is three times as the wave energy; thus, a 50/50 beam splitter is to cause a photon to lose half of a quarter, or 1/8, of its initial wave energy.
Stress transfer outpaces injection-induced aseismic slip and triggers seismicity
Authors: Yang Yuyun , Yang Hongfeng , Zi Jinping 
Published: October 2023

AbstractAs concerns rise over damaging earthquakes related to industrial activities such as hydraulic fracturing, geothermal energy extraction and wastewater disposal, it is essential to understand how subsurface fluid injection triggers seismicity even in distant regions where pore pressure diffusion cannot reach. Previous studies suggested long-range poroelastic stressing and aseismic slip as potential triggering mechanisms. In this study, we show that significant stress transfer far ahead of injection-induced aseismic slip can travel at much higher speeds and is a viable mechanism for distant earthquake triggering. It could also explain seismicity migration that is much faster than aseismic slip front propagation. We demonstrate the application of these concepts with seismicity triggered by hydraulic fracturing operations in Weiyuan shale gas field, China. The speed of stress transfer is dependent on the background stress level and injection rate, and can be almost an order of magnitude higher than that of the aseismic slip front.
Serum anti-phospholipase A2 receptor antibody in pathological diagnosis of type 2 diabetes mellitus patients with proteinuria
Authors: Zhang Huanhuan , Zhu Yuanjie , Hu Zhijuan , Liu Qiong 
Published: October 2023

AbstractPatients with diabetes mellitus complicated with proteinuria can be diabetic nephropathy (DN), diabetic complicated with non-diabetic kidney disease (NDKD), or DN with NDKD. Among these membranous nephropathy accounted for a large proportion of DN with NDRD. At present, serum anti-phospholipase A2 receptor (PLA2R) antibody is widely used in the diagnosis and evaluation of therapy in idiopathic membranous nephropathy, our study aimed to investigate the diagnostic significance of anti-PLA2R antibody in type 2 diabetes mellitus (T2DM) patients with proteinuria, providing a method for patients with contraindications of kidney biopsy. Eighty-seven T2DM patients with proteinuria who went on kidney biopsy were divided into the DN group, idiopathic membranous nephropathy (IMN) group, and others group according to their pathological results. In our study, 52.87% and 28.74% of patients were found to have IMN and diabetic nephropathy respectively. The levels of anti-PLA2R antibody, total cholesterol, triglyceride, and estimated glomerular filtration rate (eGFR) were higher in the IMN group, while the prevalence of diabetic retinopathy (DR), systolic blood pressure (SBP) and HbA1c were higher in the DN group. For T2DM patients with proteinuria, anti-PLA2R antibody (AUC = 0.904, 95%CI 0.838–0.970) has a high diagnostic value for IMN. The duration of diabetes (OR = 0.798, P = 0.030), eGFR level (OR = 1.030, P = 0.024), and positive anti-PLA2R antibody (OR = 72.727, P < 0.001) favor the diagnosis of IMN, while DR (OR = 50.234, P < 0.001), SBP (OR = 1.041, P = 0.030), and negative anti-PLA2R antibody (OR = 0.008, P  = 0.001) is beneficial to the diagnosis of DN. Our study found that NDKD is not uncommon in patients with T2DM and proteinuria, and IMN was the main pathological type. Positive anti-PLA2R antibody has a strong accuracy in the diagnosis of IMN in patients with T2DM and proteinuria.
Solution processed multi-layered thin films of Ge20Sb5S75 and Ge20Sb5Se75 chalcogenide glasses
Authors: Jemelka Jiri , Palka Karel , Janicek Petr , Slang Stanislav , Jancalek Jiri , Kurka Michal , Vlcek Miroslav 
Published: October 2023

AbstractSolution processed non-toxic Ge20Sb5Se75 chalcogenide glass thin films were deposited using spin-coating method from n-propylamine—methanol solvent mixture in specular optical quality. Optical properties, composition, structure, and chemical resistance were studied in dependence on the annealing temperature. Significant increase of refractive index and chemical resistance caused by thermoinduced structural polymerization and release of organic residua were observed. The high chemical resistance of hard-baked thin films allowed repeated direct depositions by spin-coating, increasing total thickness. Multilayered thin films of amorphous Ge20Sb5Se75 and Ge20Sb5S75 were also successfully prepared by direct deposition for the first time. Solution based deposition of non-toxic Ge20Sb5Se75 thin films in specular optical quality significantly widens the applicability of solution processed chalcogenide glass thin films. Moreover, solution based direct deposition of different glasses on hard-baked thin films opens the way to simple and cost-effective preparation of more sophisticated optical elements (e.g. beam splitters, photonic mirrors).
Dynamic modeling of geological carbon storage in an oil reservoir, Bredasdorp Basin, South Africa
Authors: Afolayan Blessing , Mackay Eric , Opuwari Mimonitu 
Published: October 2023

AbstractGeological carbon storage provides an efficient technology for the large-scale reduction of atmospheric carbon, and the drive for net-zero emissions may necessitate the future usage of oil reservoirs for CO2 projects (without oil production), hence, dynamic modeling of an oil reservoir for CO2 storage in the Bredasdorp basin, South Africa, was therefore conducted. Injection into the reservoir was for 20 years (2030–2050), and 100 years (2050–2150) to study the CO2–brine–oil interactions, with sensitivities carried out on reservoir boundary conditions. The closed boundary scenario experienced pressure buildup with a target injection rate of 0.5 Mt/year, and a cutback on injection rate progressively until 2050 to not exceed the fracture pressure of the reservoir. The CO2 plume migration was not rapid due to the reduced volume of CO2 injected and the confining pressure. The system was gravity dominated, and gravity stability was not attained at the end of the simulation as fluid interfaces were not yet flat. The open boundary reservoir did not experience a pressure buildup because all boundaries were open, the target injection rate was achieved, and it was a viscous-dominated system. In both cases, the dissolution of CO2 in oil and brine was active, and there was a growing increase of CO2 fraction dissolved in water and oil, a decline in gaseous mobile CO2 phase between 2050 and 2150, and active trapping mechanisms were structural trapping, dissolution in oil and water, and residual trapping. The study showed that boundary condition was very crucial to the success of the project, with direct impacts on injection rate and pressure. This pioneering study has opened a vista on the injection of CO2 into an oil reservoir, and CO2–brine–oil interactions, with sensitivities carried out on reservoir boundary conditions in a closed and an open hydrocarbon system in South Africa.
Functional consequences of A-to-I editing of miR-379 in prostate cancer cells
Authors: Voss Gjendine , Cassidy James R. , Ceder Yvonne 
Published: October 2023

AbstractProstate cancer is the predominant cause of cancer in men, but there is still a lack of biomarkers and treatments for metastatic spread. The initial promise of microRNAs to provide avenues to solve these problems has been dampened by the realisation that microRNAs co-exist in multiple functionally distinct isoforms, for example due to A-to-I editing. We recently found that A-to-I-editing of microRNA-379 (miR-379) was associated with prostate cancer, and that only the unedited isoform was negatively correlated with aggressive disease. Here, we set out to decipher the biological effects of unedited and edited miR-379 in prostate cancer cells. After transfection of four different prostate cancer cell lines with isoform-specific miR-379 mimics, we performed assays for cell growth, colony formation, migration, cell–cell adhesion, and analysed epithelial–mesenchymal transition (EMT) and stemness markers. We found that unedited miR-379 affected cell growth, with a promoting function in androgen receptor (AR)-negative cells and an inhibiting effect in AR-positive cells. This is supported by our in silico analysis that found unedited miR-379 targets are predicted to be predominantly involved in cellular proliferation whereas the targets of edited miR-379 are not. We further found that both miR-379 isoforms could promote colony formation, migration, and cell–cell adhesion. Overall, our data suggests that editing of miR-379 attenuates the growth-suppressive function of unedited miR-379 in androgen-sensitive prostate cancer cells, thereby promoting tumor growth.
Clinical characteristics, radiologic features, and histopathology of biopsied lacrimal gland tumors
Authors: Aryasit Orapan , Amornthatree Pawarin , Tsutsumi Wantanee Dangboon , Sittivarakul Wantanee , Geater Alan Frederick , Tengtrisorn Supaporn , Prapakornkovit Virintorn 
Published: October 2023

AbstractHerein, we described the clinicopathologic and radiologic features of biopsied lacrimal gland tumors. A retrospective case series of 79 patients treated between 2004 and 2021 was reviewed. The median age was 48.9 years (range 18.3–88.3 years), with 51.9% females. The histopathologic diagnoses were as follows: immunoglobulin G4-related disease (IgG4-RD) = 23, reactive lymphoid hyperplasia = 14, lymphoma = 14, nonspecific inflammation = 10, adenoid cystic carcinoma (ACC) = 9, and pleomorphic adenoma = 9. The proportion of histopathologic diagnoses did not differ significantly over the range of symptom durations (≤ 1 month, > 1–3 months, > 3 months). Patients with ACC had significantly shorter symptom duration and more frequent proptosis than those with pleomorphic adenoma (p = 0.040 and p = 0.009, respectively). Patients with IgG4-RD were older (median 54.3 years) than those with nonspecific inflammation (36.2 years; p = 0.046). Patients with ACC were more likely to present with diplopia than those with lymphoma (p < 0.001). The superior wedge sign increased the likelihood of ACC compared with that of non-epithelial non-malignant lacrimal gland tumors (relative risk ratio = 13.44, p = 0.002). The overall survival of patients with ACC and lymphoma did not differ significantly. Although these patients present with a short symptom duration, urgent orbital imaging, tissue biopsy, and prompt treatment should be performed in patients with lacrimal gland tumors.
Distinctive features of the oropharyngeal microbiome in Inuit of Nunavik and correlations of mild to moderate bronchial obstruction with dysbiosis
Authors: Flahaut Mathilde , Leprohon Philippe , Pham Nguyen Phuong , Gingras Hélène , Bourbeau Jean , Papadopoulou Barbara , Maltais François , Ouellette Marc 
Published: October 2023

AbstractInuit of Nunavik are coping with living conditions that can influence respiratory health. Our objective was to investigate associations between respiratory health in Inuit communities and their airway microbiome. Oropharyngeal samples were collected during the Qanuilirpitaa? 2017 Inuit Health Survey and subjected to metagenomic analyses. Participants were assigned to a bronchial obstruction group or a control group based on their clinical history and their pulmonary function, as monitored by spirometry. The Inuit microbiota composition was found to be distinct from other studied populations. Within the Inuit microbiota, differences in diversity measures tend to distinguish the two groups. Bacterial taxa found to be more abundant in the control group included candidate probiotic strains, while those enriched in the bronchial obstruction group included opportunistic pathogens. Crossing taxa affiliation method and machine learning consolidated our finding of distinct core microbiomes between the two groups. More microbial metabolic pathways were enriched in the control participants and these were often involved in vitamin and anti-inflammatory metabolism, while a link could be established between the enriched pathways in the disease group and inflammation. Overall, our results suggest a link between microbial abundance, interactions and metabolic activities and respiratory health in the Inuit population.
Influence of the Mn5Ge3/Ge ohmic-contact interface on the Seebeck coefficient of the Mn5Ge3/Ge bilayer
Authors: Portavoce Alain , Hassak Siham , Bertoglio Maxime 
Published: October 2023

AbstractThermoelectricity is a well-known effect that can be used to convert heat energy into electrical energy. However, the yield of this conversion is still low compared to current photovoltaic technology. It is limited by the intrinsic properties of materials, leading to intensive materials science investigations for the design of efficient thermoelectric (TE) materials. Interface engineering was shown to be a valuable solution for improving materials’ TE properties, supporting the development of multiphase TE materials. In particular, interfaces have been suggested to promote the increase of the Seebeck coefficient of materials without significantly impacting their electrical conductivity through the so-called energy filtering effect. This work aims at determining experimentally the effect of a metal/semiconductor interface exhibiting an ohmic character on the effective Seebeck coefficient of multiphase materials, focusing on the n-type Mn5Ge3/p-type Ge interface. This interface is shown not to contribute to carrier transport, but to contribute to carrier concentration filtering due to carrier injection or recombination. The Seebeck coefficient of the bi-phase material is shown to be dependent on the direction carriers are crossing the interface. The interface effect mainly results from a modification of charge carrier concentrations in the semiconductor.