bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of flunarizine combined with ginkgo leaf extract and dipyridamole injection on hemorheology in elderly patients with vertigo
Authors: Liu Xinlei , Shu Lingyu , Zheng Junxia 
Published: December 2023

Objective: To investigate the effect of flunarizine combined with ginkgo leaf extract and dipyridamole injection (GDI) on hemorheology of elderly patients with vertigo.
Methods: Clinical data of 105 elderly patients with vertigo who were treated in The First People’s Hospital of Lin’an District from June 2019 to December 2022 were retrospectively selected. Of them, 54 patients received flunarizine combined with GDI (Study group) while 51 patients received flunarizine treatment alone (Control group). The treatment effect and adverse reactions of the two groups, functional rehabilitation before and after treatment, including the Simplified Vertigo Symptom Score Scale (VSS-SF), Berg Balance Scale (BBS), and Dizziness Handicap Inventory (DHI) were measured. Hemodynamics including blood flow velocity (Vm) of basilar artery (BA), left vertebral artery (LVA), and right vertebral artery (RVA) before and after treatment were also assessed.
Results: The total efficacy of the treatment in the study group was higher than that in the control group (94.4 % vs. 75.9%; P<0.05). After the treatment, the Vm of the BA, LVA, and RVA was increased in both groups compared to before treatment, and the increase was greater in the study group than in the control group (P<0.05). In addition, the BBS scores of the two groups after the treatment were higher than before the treatment, while the DHI and VSS-SF scores were lower than before the treatment. BBS scores of the study group were higher than those of the control group, while the DHI and VSS-SF scores were lower than those of the control group (P<0.05). There was no statistically significant difference in the incidence of adverse reactions between the study group (5.6%) and the control group (2.0%; P>0.05).
Conclusions: The combination of flunarizine and GDI in elderly patients with vertigo can effectively regulate hemodynamics of the patient, reduce the degree of vertigo, improve balance, and have a significant overall therapeutic effect without increasing the risk of adverse reactions.
doi: https://doi.org/10.12669/pjms.40.3.8456
How to cite this: Liu X, Shu L, Zheng J. Effects of flunarizine combined with ginkgo leaf extract and dipyridamole injection on hemorheology in elderly patients with vertigo. Pak J Med Sci. 2024;40(3):---------. doi: https://doi.org/10.12669/pjms.40.3.8456
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Centralized healthcare database for ensuring better healthcare: Are we lagging behind?
Authors: Tariq Sundus , Tariq Saba , Shoukat Ahmad Adnan 
Published: December 2023

doi: https://doi.org/10.12669/pjms.40.3.9084
How to cite this: Tariq S, Tariq S, Shoukat AA. Centralized healthcare database for ensuring better healthcare: Are we lagging behind? Pak J Med Sci. 2024;40(3):---------. doi: https://doi.org/10.12669/pjms.40.3.9084
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Acute Alcohol-Induced Pancreatitis After Transcoronary Alcohol Ablation
Authors: Cubillan Mark Patrick , Raphael Kara 
Published: December 2023

ABSTRACT
Alcohol-induced pancreatitis typically presents as acute nausea, vomiting, and abdominal pain, typically seen as a complication of chronic alcoholism or binge drinking alcoholic beverages. Here, we present a case of alcohol-induced pancreatitis from an unusual source: alcohol used in a catheter ablation for atrial fibrillation. This is the first case in current literature that has identified this adverse effect of alcohol catheter ablation.
Acute Cholangitis Masquerading Biliary Neuroendocrine Carcinoma: A Rare Twist to a Typical Presentation
Authors: Nagi Talwinder , Suarez Zoilo K. , Haider Muhammad Adnan , Vallejo Charles , Hernandez Oscar , Doukides Theodore 
Published: December 2023

ABSTRACT
Biliary neuroendocrine carcinoma (BNEC) develops in the biliary tract and is characterized by the presence of neuroendocrine cells and account for less than 1% of all malignancies. We present a patient with no significant risk factors of BNEC who presented with abdominal pain and jaundice. An endoscopic ultrasound with endoscopic retrograde cholangiopancreatography was concerning for neoplasm and less likely Mirizzi syndrome. Pathology revealed well-differentiated grade 3 large-cell neuroendocrine carcinoma of the common bile duct. BNEC has a poor prognosis with a reported 5-year survival rate of less than 20%, which is worse than other biliary tract malignancies such as cholangiocarcinoma. Additional cases and further studies of multimodal treatment are required in the future to improve prognosis. Providers should be aware of the risk factors of BNEC and consider the diagnosis when evaluating patients with the symptoms above.
Refractory Cytomegalovirus Colitis Followed by De Novo Inflammatory Bowel Disease Post-Orthotopic Liver Transplantation
Authors: Selvan Bharathi , Pendse Avani A. , Zhang Cecelia , Cauthen Jeffriann , Kappus Matthew R. , Messina Julia A. 
Published: December 2023

ABSTRACT
Cytomegalovirus (CMV) and inflammatory bowel disease (IBD) are both immune-mediated complications that affect orthotopic liver transplantation patients. In this report, we present a 60-year-old man who underwent orthotopic liver transplantation for cryptogenic cirrhosis with serologies notable for CMV-seropositive donor and seronegative recipient. His post-transplant course was initially complicated by probable refractory CMV colitis. However, his gastrointestinal symptoms persisted, eventually leading to a diagnosis of post-transplant de novo IBD. The discussion highlights theories regarding the association between CMV and IBD, a topic that has been widely debated for decades.
Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy–Associated Hepatitis
Authors: Mesbah Zhubene , Tiwari Nishant , Sacco Keith 
Published: December 2023

ABSTRACT
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is an inborn error of immunity, resulting from variation in the autoimmune regulator gene (AIRE). Pathogenic variants in the AIRE gene result in autoimmunity typically involving endocrine organs with nonendocrine organs less commonly affected. Hepatitis associated with APECED has emerged as a potentially fatal complication with higher reported prevalence in the Americas. We describe a case of a 3-year-old boy presenting with hepatitis from APECED without classical clinical diagnostic criteria. This case highlights the importance of APECED in the evaluation of hepatitis given response to immunomodulator treatment and risk of fulminate liver failure.
Product Quality and Product Compatibility in Network Industries
Authors: Buccella Domenico , Fanti Luciano , Gori Luca 
Published: December 2023

Abstract
Using an appropriate game-theoretic approach, this article develops a non-cooperative two-stage game in a Cournot duopolistic network industry in which firms strategically choose whether to produce compatible goods in the first decision-making stage. Quality differentiation affects the sub-game perfect Nash equilibrium (SPNE): (i) the network effect acts differently between low- and high-quality firms, depending on their compatibility choice; (ii) if the network externality is positive (resp. negative), to produce compatible (resp. incompatible) goods is the unique SPNE; however, this equilibrium configuration leads the high-quality firm to be worse off; (iii) there is room for a side payment from the high- to the low-quality firm to deviate toward incompatibility (resp. compatibility) under positive (resp. negative) network externality. This payment represents a Pareto improvement on the firm side but not from a societal perspective, as consumers would be worse off. The article also pinpoints the social welfare outcomes corresponding to the SPNE.
Effects of plant density on alfalfa (Medicago sativa L.) seed yield in western Heilongjiang areas
Authors: Wang Xiaolong , Zhong Peng , Yang Zhao , Lai Yongcai , Li Shasha , Chai Hua , Xu Yanxia , Wu Yue , Wang Jianli 
Published: December 2023

Abstract
Alfalfa (Medicago sativa L.) is known as the “king of forages”. The aim of the current study is to determine the optimum planting density as the key cultivation technique for high yield of alfalfa seed. Alfalfa variety (Longmu 801) was planted in experimental fields from 2014 to 2017. In the planting density test, the row spacing was 65, 80, and 95 cm, and the plant spacing was 30, 45, 60, 75, and 90 cm. The seed yield and yield components in the row spacing and plant spacing tests were measured. On the basis of 3 years average of the experimental data, the highest seed yield of 225.49 kg ha−1 was obtained with row spacing vs plant spacing of 65 and 60 cm, respectively. Correlation analysis showed a significant positive correlation between the racemes per stem, pods per raceme, pods per stem, seeds per pod, and the seed yield. These results suggested that Longmu 801 should be cultivated with 65 cm row spacing and 60 cm plant spacing to maximize seed yields in western Heilongjiang areas.
Daily load curve prediction for Jordan based on statistical techniques
Authors: Momani Mohammad Awad , Alhmoud Lina 
Published: December 2023

AbstractThe article proposes a mathematical prediction model for daily load curves (DLCs) in Jordan from 2023–2050. The historical hourly peak loads based on the growth rate statistical method in 1994–2020 and the annual forecasted peak loads during the morning and evening periods taken from the long-term load forecast (LTLF) study of National Electric Power Company (NEPCO) during 2022–2050 are employed in the prediction model. The results show that the actual hourly growth rates, the annual forecasted growth rates, and the hourly peak loads in the reference year 2022 are the main input variables used in the prediction formula. The LTLF study conducted by NEPCO employs various sophisticated methods depending on the end-user sectorial electricity consumption that imply an econometric approach, market survey, and Gomprtz extrapolation techniques. The peak load in Jordan relies upon several climatic and nonclimatic variables, implying the ambient temperature, gross domestic product, income, demographic, urbanization, electricity tariff, average oil prices, and other factors related to technology and new aspects of energy saving and space heating/cooling systems, the DLC in Jordan is variable and changing from year to year. The proposed model considers a variation in the future DLC and suggests three different scenarios of DLC’s prediction based on the time occurrence of the peak load: the first is the daytime peak occurrence scenario, the second is the evening peak occurrence scenario, and finally is the daytime and evening peaks may be close to each other.
Variation and change in the Swedish periphrastic passive: a constructional approach
Authors: Skrzypek Dominika 
Published: December 2023

Abstract
This paper examines the development of the periphrastic passive voice construction in Swedish between 1300 and 1750, from the point of view of constructional change. The development involves the rise of a new auxiliary, bliva ‘remain’, originally a lexical loan from Middle Low German, which after a period of variation replaces the older auxiliary varda ‘become’. The findings reveal that the origins of the periphrastic passive construction may be found in mutative constructions with varda and adjectival complements, and the same development is then found with the loanword bliva, delayed by some hundred years. The results of quantitative analysis place the turning point in the development between 1450 and 1550. The paper relates the variation and change in passive auxiliaries to Diachronic Construction Grammar.
Walkaway vertical seismic profiling first-arrival traveltime tomography with velocity structure constraints
Authors: Cai Lu , Chunlong Zhang , Zhibin Zhang 
Published: December 2023

Abstract
Walkaway vertical seismic profiling (WVSP) is known for its high level of credibility in obtaining the relationship between first-arrival traveltime and detector depth through first-arrival picking. This relationship can be utilized for seismic velocity model inversion to improve velocity model accuracy and rationality. Here, we present a WVSP first-arrival velocity model with velocity structure constraints, by utilizing layer and fault data interpreted by ground seismic structure technique. We constructed a geological structure and layer sequence models based on sedimentary patterns to obtain complex velocity structures. Furthermore, we introduced a smooth regularization term based on the velocity structure into the inversion model to enhance its consistency with geological laws and compensate for the reduced inversion accuracy owing to the regularization term based on flat structures. This approach addressed the limitations of the regularization term based on flat structures, resulting in more accurate and reliable inversion results. Through simulation analysis, the proposed method realized the WVSP first-arrival velocity inversion, with results being closer to those of the real velocity model.
Green synthesis of silver nanoparticles using Saccharum officinarum leaf extract for antiviral paint
Authors: Noppradit Benjaporn , Chaiyosburana Setsiri , Khupsathianwong Nutthaphol , Tapachai Weena Aemaeg , Wattanakanjana Yupa , Phengdaam Apichat 
Published: December 2023

Abstract
In this study, silver nanoparticles (AgNPs) were synthesized via an eco-friendly approach using an extract from sugarcane leaves (Saccharum officinarum). The optimal synthesis conditions were determined to be a pH of 10, yielding AgNPs with an average size of 11.7 ± 2.8 nm. This was substantiated by UV-vis spectral analysis, transmission electron microscopy, and field emission transmission electron microscope coupling with selected area electron diffraction. The synthesized AgNPs exhibited notable antibacterial efficacy against two prominent pathogens, namely Staphylococcus aureus and Escherichia coli, with minimum inhibitory concentration values of 20 and 2.5 ppm, respectively. Further extending the applications of AgNPs, they were successfully integrated into architectural paints at varying concentrations to create antiviral coatings. The addition of AgNPs influenced several properties of the paints, including viscosity, hiding power, and color characteristics. Notably, our findings revealed that the antiviral paint containing 80 ppm of AgNPs effectively hindered virus propagation, exhibiting a remarkable reduction of over 90% when compared to the control, measured by 50% tissue culture infectious dose.
Possibility of metallic cobalt formation in the oxide scale during high-temperature oxidation of Co-27Cr-6Mo alloy in air
Authors: Wongpromrat Patthranit , Tunthawiroon Phacharaphon , Bumrungthaichaichan Eakarach , Ponpo Phisan , Nilsonthi Thanasak , Chandra-ambhorn Somrerk , Chandra-ambhorn Walairat 
Published: December 2023

Abstract
Co-based alloys are known to be high oxidation-resistant material and used in several high temperature applications. During high temperature oxidation, duplex oxides containing Co and Cr were formed. It was thermodynamically elucidated that when the growing scale was thick enough, the partial pressure of O2 in the scale dropped. Then, the reduction of CoO occurred for promoting O2 which was responsible for Cr2O3 production. This work experimentally proved this point by in situ characterising Co-27Cr-6Mo at high temperatures in air by X-ray diffractometer in a grazing incident mode and metallic Co was confirmed to be formed by the reduction of CoO consistent with the image taken and analysed by field emission scanning electron microscope, energy-dispersive X-ray, and electron backscatter diffraction. Furthermore, the change in lattice parameter and the phase transition were observed when the temperature was altered.
Endovascular repair of the aortic arch
Authors: Kursch Florian , Doukas Panagiotis 
Published: December 2023

Abstract

Objectives
The gold standard for the treatment of pathologies of the aortic arch remains the open surgical reconstruction of the affected segments. However, endovas-cular treatment options have emerged that eliminate the need for invasive open surgery. Several endograft devices – with fenestrations or branches for the supraaortic vessels – are currently available to address different pathologies and anatomical variations. Parallel-graft techniques and in situ fenestrations expand the treatment options for emergent cases. In this selective review of the literature of 2020 and 2021, we summarize the current chances and challenges of endovascular aortic repair.

Content
Reported mortality rates range from 0 to 13.2 %. Although technical success rates for fenestrated and branched devices are promising (98 %), stroke rates remain a relevant issue (10 and 3 % for BTEVAR and FTEVAR respectively). The reported technical success rate for in situ fenestrations is also encouraging (94 %) and the stroke rates acceptable (5 %). Parallel-graft techniques are associated with high early and late endoleak rates (early 76 %; late 31 %), but still hold a valuable place in the treatment of emergent cases or in bail-out situations.

Summary and Outlook
The endovascular repair of the aortic arch expands the range of patients with pathologies of the arch eligible for treatment to those unfit for open surgery offering a minimally invasive, yet technically challenging procedure. More data and meta-analyses are needed to define the benefits and drawbacks of this promising treatment option in an aging population with increasing co-morbidities.
On the influence of the fourth order orientation tensor on the dynamics of the second order one
Authors: Papenfuss Christina 
Published: December 2023

Abstract
The consequences of introducing the fourth order orientation tensor as an independent variable in addition to the second order one are investigated. In the first part consequences of the Second Law of Thermodynamics are exploited. The cases with the second order alignment tensor in the state space on one hand and with the second and fourth order alignment tensors on the other hand are analogous. In the latter case differential equations for the second and fourth order tensors result from linear force-flux relations with a coupling arising due to coupling terms in the free energy. In the second part the differential equations for the second order orientation tensor or the second and fourth order orientation tensors, respectively are given explicitly in the special case of a rotation symmetric orientation distribution. The Folgar-Tucker equation with a quadratic closure relation leads to a Riccati equation for the second order parameter. In comparison the Folgar-Tucker equation and the differential equation for the fourth order parameter are considered. The fourth order parameter is eliminated later. The resulting equation for the second order parameter is a Duffing equation with a behavior of solutions completely different from the solutions of the Riccati equation.
Effect of particle size on the properties of avocado pear wood fiber/low-density polyethylene composite enhanced by pretreatment
Authors: Government Rabboni Mike , Okeke Edozie Thompson 
Published: December 2023

Abstract
The work entailed the influence of particle size on the characteristics and water absorption resistance of avocado pear wood fiber/low-density polyethylene (APWF/LDPE) composite enhanced by pretreatment. The fiber particle of 100, 80, 60, 40, and 20 mesh (150, 180, 250, 425, and 850 µm) for the avocado wood fiber (APWF) was infused in the resin. Each particle of the fiber with fiber content of 5–25 wt% for the untreated, pretreated with NaOH, NaOH + CH3COOH, and NaOH + CH3COOH + MAPE was intermixed in the resin to produce the APWF/LDPE composites, respectively. The APWF/LDPE composites were analyzed on the properties, water absorption resistance, Fourier transform infra-red, and scanning electron microscopy. The study exhibited that mechanical properties and water absorption resistance of the APWF/LDPE composite were improved at lower particle of the fiber triggered by treatment. The best properties were confirmed at 150 µm of APWF pretreated with NaOH + CH3COOH + MAPE when compounded with the resin. These were proportional to 15.92 MPa, 0.867 GPa, 41.39 MPa, 0.662 GPa, 683 Pa, 84.04 kJ m−2, and 2.44 % for tensile strength, elastic modulus, flexural strength, bending modulus, Brinell hardness, impact strength, and water absorption resistance, respectively. The APWF/LDPE composite for NaOH + CH3COOH + MAPE pretreated is recommended for interior cabinet of an automobile.
Abnormal evolution of resistivity and microstructure of annealed Ag nanoparticles/Ag–Mo films
Authors: Li Saibo , Liang Shihao , Han Chao , Sun Haoliang , Wang Guangxin 
Published: December 2023

Abstract
Ag–Mo films with different thicknesses were prepared on polyimide substrate by magnetron sputtering and annealed at different temperatures. The effects of film thickness and annealing temperatures on the resistivity and microstructure of Ag–Mo alloys were investigated. Results show that many Ag nanoparticles were self-formed on Ag–Mo films’ surface. As the thickness of the Ag–Mo film increased from 163 to 409 nm, there was a significant decrease in its resistivity, dropping from 485.44 to 237.12 μΩ cm. Resistivity of the Ag–Mo film is dependent on the annealing temperature. When temperature rises from room temperature to 180℃, the resistivity decreases from 390.62 to 339.37 μΩ cm, with little change. After annealing above 270℃, a sudden increase of resistivity of the Ag–Mo film was attributed to the growth of Ag particles on the film surface contributing to the increase in surface roughness, which hindered electron transport and caused severe surface scattering. High-resistivity Ag–Mo films are expected to be candidates for high-resistivity thin-film devices.
Development of graphene and graphene quantum dots toward biomedical engineering applications: A review
Authors: Handayani Murni , Hendrik  , Abbas Aumber , Anshori Isa , Mulyawan Rahmat , Satriawan Ardianto , Shalannanda Wervyan , Setianingsih Casi , Pingak Charline Tiara Rehuellah , Zahro Qurriyatus , Rurisa Ayu Candra Sekar , Setiawan Iwan , Khotimah Khusnul , Sunnardianto Gagus Ketut , Rahmayanti Yosephin Dewiani 
Published: December 2023

Abstract
Research on the application of graphene (G) and graphene quantum dots (GQDs) for biomedical engineering has attracted much attention over the last decade. Graphene and its derivatives have shown great biocompatibility, solubility, selectivity, large surface area, high purity, biofunctionalization, high drug loading capacity, and cell membrane penetration capability potential to be applied in biomedical engineering areas. The unique physical and chemical properties of GQDs, including small size, chemical inertness, high photoluminescence stability, low cytotoxicity, and good biocompatibility, made them a promising candidate for biomedical engineering applications. The recent progress related to the development of G and GQDs toward biomedical engineering applications is presented in this work. This study reviews and discusses the development of G and GQDs, both top-down and bottom-up synthesis methods, for biomedical engineering applications, such as biosensing, tissue engineering, drug delivery, bioimaging, antibacterial, and antiviral.