bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bacteremic Infection with
Pantoea ananatis
Authors: De Baere Thierry , Verhelst Rita , Labit Caroline , Verschraegen Gerda , Wauters Georges , Claeys Geert , Vaneechoutte Mario 
Published: September 2004

ABSTRACT

A 73-year-old man was hospitalized for dyspnea and bilateral ankle edema. During his hospital stay he presented anal hemorrhage and developed a high fever after colonoscopy. A set of aerobic and anaerobic blood culture bottles yielded a pure culture of gram-negative rods, susceptible to all antibiotics tested. The API20E code was 1005133, resulting in a very good identification as
Pantoea
sp. Subsequent sequencing of the 16S rRNA gene revealed a final identification as
Pantoea ananatis.
The patient was given intravenous and oral therapy with piperacillin-tazobactam and ofloxacin and recovered completely from his infection.
Streptococcus porcinus
as a Cause of Spontaneous Preterm Human Stillbirth
Authors: Martin Christian , Fermeaux Véronique , Eyraud Jean-Luc , Aubard Yves 
Published: September 2004

ABSTRACT

We report, to our knowledge, on the first case of a woman suffering stillbirth due to
Streptococcus porcinus
on the basis of microbiologic and histologic data.
Continuous Ambulatory Peritoneal Dialysis-Related Peritonitis Associated with Lancefield Group G Beta-Hemolytic Streptococcus: Report of Two Cases Requiring Tenckhoff Catheter Removal
Authors: Woo Patrick C. Y. , Wong Samson S. Y. , Lau Susanna K. P. , Yuen Kwok-yung 
Published: September 2004

ABSTRACT
We describe the first two cases of continuous ambulatory peritoneal dialysis-related peritonitis associated with Lancefield group G beta-hemolytic streptococci in the literature. Both patients presented with abdominal pain and turbid dialysis effluent with or without fever. Both had concomitant gastrointestinal tract disturbance. Both did not respond to intraperitoneal cefazolin and tobramycin and required removal of the Tenckhoff catheters.
Rapid Identification of
Mycobacterium genavense
with a New Commercially Available Molecular Test, INNO-LiPA MYCOBACTERIA v2
Authors: Trueba François , Fabre Michel , Saint-Blancard Patrick 
Published: September 2004

ABSTRACT

We report a rare mesenteric localized
Mycobacterium genavense
infection in a severely immunocompromised human immunodeficiency virus-infected patient. An INNO-LiPA MYCOBACTERIA v2 test was performed directly on biopsy samples. This new molecular tool could be used for simultaneous identification of mycobacterium species from human specimens, but other studies are needed to validate our first results.
Campylobacter fetus
of Reptile Origin as a Human Pathogen
Authors: Tu Zheng-Chao , Zeitlin Gary , Gagner Jean-Pierre , Keo Thormika , Hanna Bruce A. , Blaser Martin J. 
Published: September 2004

ABSTRACT

A
Campylobacter
species was isolated from blood from a febrile patient with precursor T-cell acute lymphoblastic leukemia, and after antibiotic treatment, a similar bacterium was isolated from blood 37 days later. Although phenotypic testing did not definitively identify the organisms, molecular analysis indicated that they were the same strain of
Campylobacter fetus
subsp.
fetus
and were of reptile origin.
Cost-Effective Method for Identification of Dimorphic Fungi
Authors: Hughes Alice D. , Lorusso Giovanni D. , Greer Donald L. 
Published: September 2004

ABSTRACT
Traditional methods to identify dimorphic fungi dictate that the mold be converted to the yeast phase at 35 to 37°C. We present a time- and cost-saving method of confirming the identification of a dimorph by using special stains to demonstrate the yeast phase directly growing in the original clinical specimens.
GAUGE THEORY DEFORMATIONS AND NOVEL YANG–MILLS CHERN–SIMONS FIELD THEORIES WITH TORSION
Authors: ANCO STEPHEN C. 
Published: September 2004

A basic problem of classical field theory, which has attracted growing attention over the past decade, is to find and classify all nonlinear deformations of linear abelian gauge theories. The physical interest in studying deformations is to address uniqueness of known nonlinear interactions of gauge fields and to look systematically for theoretical possibilities for new interactions. Mathematically, the study of deformations aims to understand the rigidity of the nonlinear structure of gauge field theories and to uncover new types of nonlinear geometrical structures. The first part of this paper summarizes and significantly elaborates a field-theoretic deformation method developed in earlier work. Some key contributions presented here are, firstly, that the determining equations for deformation terms are shown to have an elegant formulation using Lie derivatives in the jet space associated with the gauge field variables. Secondly, the obstructions (integrability conditions) that must be satisfied by lowest-order deformations terms for existence of a deformation to higher orders are explicitly identified. Most importantly, a universal geometrical structure common to a large class of nonlinear gauge theory examples is uncovered. This structure is derived geometrically from the deformed gauge symmetry and is characterized by a covariant derivative operator plus a nonlinear field strength, related through the curvature of the covariant derivative. The scope of these results encompasses Yang–Mills theory, Freedman–Townsend theory, and Einstein gravity theory, in addition to their many interesting types of novel generalizations that have been found in the past several years. The second part of the paper presents a new geometrical type of Yang–Mills generalization in three dimensions motivated from considering torsion in the context of nonlinear sigma models with Lie group targets (chiral theories). The generalization is derived by a deformation analysis of linear abelian Yang–Mills Chern–Simons gauge theory. Torsion is introduced geometrically through a duality with chiral models obtained from the chiral field form of self-dual (2+2) dimensional Yang–Mills theory under reduction to (2+1) dimensions. Field-theoretic and geometric features of the resulting nonlinear gauge theories with torsion are discussed.
ROLE OF MARKET BASED INSTRUMENTS IN THE NEW BUSINESS PARADIGM
Authors: AZZOLINI LUCIANO , KHARE ANSHUMAN 
Published: September 2004

This paper attempts to develop a prescriptive theory/model for the strategic application of market based policy instruments. The research paper documents the development of command and control regulatory instruments and provides a normative account of their use by businesses for competitive positioning. The paper then reports the development of Market Based Policy Instruments (MBI) and explains their prospective defensive and offensive strategic applications based on Porter's Five Forces model of industry analysis. Finally, a prescriptive model that describes the strategic application of MBI is provided based on the preceding analysis. It is assumed that successful firms will not shy away or avoid future regulatory instruments but use them to their competitive advantage. That competitive advantage will come from core firm values that emphasize dramatic increases in resource productivity, the elimination of waste, the use of solution-based business models, and reinvestment in the natural capital. The strategies and tactics that will guide the evolution of "laggard" firms into "achiever" and "enviropreneurial" firms is not precisely mapped out, but there are a number of tools, tactics and strategies that firms can use. All of them are applicable depending on the managerial maturity of the firm and its capacity to extend its environmental management practices, strategy and vision throughout its organisation and to its constellation of relationships. Firms looking for unique competitive advantages should consider using market based regulatory instruments to differentiate their products and services to overcome seemingly impossible market entry barriers, reduce operating costs, and turn waste into profit.
Suppression of Graft Coronary Artery Disease by a Brief Treatment With a Selective εPKC Activator and a δPKC Inhibitor in Murine Cardiac Allografts
Authors: Tanaka Masashi , Terry Raya D. , Mokhtari Golnaz K. , Inagaki Koichi , Koyanagi Tomoyoshi , Kofidis Theo , Mochly-Rosen Daria , Robbins Robert C. 
Published: September 2004

Background—Inhibiting delta protein kinase C (δPKC) during reperfusion and activating epsilon PKC (εPKC) before ischemia each limits cardiac ischemic injury. Here, we examined whether limiting ischemia-reperfusion injury inhibits graft coronary artery disease (GCAD) and improves murine cardiac allografting.Methods and Results—Hearts of FVB mice (H-2q) were transplanted into C57BL/6 mice (H-2b). εPKC activator (ψεRACK) was injected intraperitoneally (20 nmol) into donor mice 20 minutes before procurement. Hearts were then perfused with ψεRACK (1.5 nmol) through the inferior vena cava (IVC) and subsequently submerged in ψεRACK (0.5 μmol/L) for 20 minutes at 4°C. Before reperfusion, the peritoneal cavity of recipients was irrigated with δPKC inhibitor (δV1-1, 300 nmol); control animals were treated with normal saline. The total ischemic time to the organ was 50 minutes. Two hours after transplantation, production of inflammatory cytokines and adhesion molecules, cardiomyocyte apoptosis, and caspase-3 and caspase-9 (but not caspase-8) activities were significantly reduced in the PKC regulator-treated group. Fas ligand levels (but not Fas) were also significantly reduced in this group. Importantly, GCAD indices, production of inflammatory cytokines, and adhesion molecules were significantly decreased and cardiac allograft function was significantly better as measured up to 30 days after transplantation.ConclusionsAn εPKC activator and a δPKC inhibitor together reduced GCAD. Clinically, these PKC isozyme regulators may be useful for organ preservation and prevention of ischemia-reperfusion injury and graft coronary artery disease in cardiac transplantation.
Effect of Chemical Treatment on the Mechanical Properties of Starch-Based Blends Reinforced with Sisal Fibre
Authors: Vallo Claudia , Kenny Jose M. , Vazquez Analia , Cyras Viviana P. 
Published: September 2004

Biocomposites were produced using polycaprolactone (PCL) and starch as the matrix, and washed and treated sisal fibres as reinforcement. The matrix consists of a biodegradable product commercially known as MaterBi-Z®, which is based on a PCL, starch and additive. Alkaline and acetylation treatments were performed on the fibre in order to enhance the adhesion degree and the compatibility between the fibre and the matrix. The effect of chemical treatment on morphology, physical and chemical properties and tensile properties of fibres and composites were determined. Tensile properties of the biodegradable composite were improved by the presence of the fibre. However, the untreated fibres behaved as better reinforcement than the acetylated and alkalitreated fibres. This was attributed to an impairment of the mechanical properties of the acetylated fibres and incompatibility of the alkali-treated fibres. The results observed are supported by SEM analysis of fibres and the composite materials.
Residual Compressive Failure Characteristics of Hybrid Composites with Nonwoven Carbon Tissue after Indentation Damage
Authors: Lee Seung-Hwan , Aono Yuuta , Noguchi Hiroshi , Cheong Seong-Kyun 
Published: September 2004

The purpose of this study is to investigate the relationship between the low-energy impact damages under static indentation loadings and the residual compressive static and fatigue strengths after damage in hybrid composites with nonwoven carbon tissue (NWCT). The hybrid laminates are made by interleaving the NWCT layer between the CFRP layer interfaces. The indentation damages were discussed by investigating the delamination areas and the indentation energies of four kinds of angle-ply laminates ([455/ 455/455] and [453/ 453/453/ 453/453] CFRP laminates, and [455// 455//455] and [453// 453//453// 453//453] hybrid laminates; the symbol “//” means that the NWCT layer is located at an interface between the CFRP layers. The delamination areas of the hybrid laminates were reduced to about half of the CFRP’s by the indentation loading (Lee, S.H., Aono, Y., Noguchi, H. and Cheong, S.K. (2003). Damage Mechanism of Hybrid Composites with Non-Woven Carbon Tissue Subjected to Quasi-Static Indentation Loads, Journal of Composite Materials, 37: 333–349). After the indentation damage, compressive static and fatigue tests are carried out using an anti-buckling guide for the angle-ply laminates. The failure modes of the angle-ply CFRP and hybrid specimens are caused by global buckling under the compressive static loading. However, the failure modes of the angle-ply CFRP and hybrid specimens at Nf <10 6cycles are caused by shearing the damaged part under the compression–compression fatigue loading. Compared with CFRP laminates, compressive fatigue lives of the hybrid laminates were significantly extended in all the stress ranges. The NWCT interleaving effect is examined based on the observations of the damage in the hybrid specimens after the indentation damage. Also, the compressive static and fatigue failure processes are discussed from the observation of the fracture surfaces of damaged parts and failed appearance of specimens when subjected to the compressive loadings after the indentation damage.
Effects of Selected Variables on Musicians’ Ratings of High-Level Piano Performances
Authors: Wapnick Joel , Ryan Charlene , Lacaille Nathalie , Darrow Alice-Ann 
Published: September 2004

The purpose of this study was to ascertain whether judgments of solo performances recorded at a well-known international piano competition would be affected by musical characteristics such as style (classic period versus early 20th-century Russian) and tempo (slow versus fast). Evaluators rated performances on six test items: tone quality, note accuracy, rhythmic accuracy, expressiveness, adherence to style and overall impression. The effects of four between-subjects variables were examined: audio versus audiovisual presentation, undergraduate versus graduate/faculty, gender, and pianists versus non-pianists. Results from the 227 evaluators revealed main effects for treatment, style and major: audiovisual presentations were rated higher than audio only presentations, performances of Russian music were rated higher than performances of classic music, and pianists rated performances higher than did non-pianists. The treatment effect was due to a significant treatment by major interaction, and applied only to non-pianists. Gender was involved in a number of three- and four-way interactions that are difficult to interpret. Pearson r correlations were calculated for ratings of the 16 performances on the overall impression test item. The mean correlation for the 120 pairs of ratings was .33 – low but statistically significant. Intraclass correlations revealed no significant differences between the two levels of all four between-subjects variables.
Reparations for ‘America’s Holocaust’: Activism for Global Justice
Authors: Martin Michael T. , Yaquinto Marilyn 
Published: September 2004

The enslavement of blacks in America lasted 246 years. It was followed by a century of legal racial segregation and discrimination. The two periods, taken together, constitute the longest running crime against humanity in the world over the last 500 years. – Randall Robinson Reparations are the central issue of race relations in America in the twentyfirst century. Until we address it seriously, we will continue to make only modest progress with some of the larger issues. – Charles J. Ogletree Jr
Iterative class discovery and feature selection using Minimal Spanning Trees
Authors: Varma Sudhir , Simon Richard 
Published: September 2004

Abstract
Background
Clustering is one of the most commonly used methods for discovering hidden structure in microarray gene expression data. Most current methods for clustering samples are based on distance metrics utilizing all genes. This has the effect of obscuring clustering in samples that may be evident only when looking at a subset of genes, because noise from irrelevant genes dominates the signal from the relevant genes in the distance calculation.

Results
We describe an algorithm for automatically detecting clusters of samples that are discernable only in a subset of genes. We use iteration between Minimal Spanning Tree based clustering and feature selection to remove noise genes in a step-wise manner while simultaneously sharpening the clustering.
Evaluation of this algorithm on synthetic data shows that it resolves planted clusters with high accuracy in spite of noise and the presence of other clusters. It also shows a low probability of detecting spurious clusters. Testing the algorithm on some well known micro-array data-sets reveals known biological classes as well as novel clusters.

Conclusions
The iterative clustering method offers considerable improvement over clustering in all genes. This method can be used to discover partitions and their biological significance can be determined by comparing with clinical correlates and gene annotations. The MATLAB© programs for the iterative clustering algorithm are available from http://linus.nci.nih.gov/supplement.html
Integrated analysis of metabolic phenotypes in Saccharomyces cerevisiae
Authors: Duarte Natalie C , Palsson Bernhard Ø , Fu Pengcheng 
Published: September 2004

Abstract
Background
The yeast Saccharomyces cerevisiae is an important microorganism for both industrial processes and scientific research. Consequently, there have been extensive efforts to characterize its cellular processes. In order to fully understand the relationship between yeast's genome and its physiology, the stockpiles of diverse biological data sets that describe its cellular components and phenotypic behavior must be integrated at the genome-scale. Genome-scale metabolic networks have been reconstructed for several microorganisms, including S. cerevisiae, and the properties of these networks have been successfully analyzed using a variety of constraint-based methods. Phenotypic phase plane analysis is a constraint-based method which provides a global view of how optimal growth rates are affected by changes in two environmental variables such as a carbon and an oxygen uptake rate. Some applications of phenotypic phase plane analysis include the study of optimal growth rates and of network capacity and function.

Results
In this study, the Saccharomyces cerevisiae genome-scale metabolic network was used to formulate a phenotypic phase plane that displays the maximum allowable growth rate and distinct patterns of metabolic pathway utilization for all combinations of glucose and oxygen uptake rates. In silico predictions of growth rate and secretion rates and in vivo data for three separate growth conditions (aerobic glucose-limited, oxidative-fermentative, and microaerobic) were concordant.

Conclusions
Taken together, this study examines the function and capacity of yeast's metabolic machinery and shows that the phenotypic phase plane can be used to accurately predict metabolic phenotypes and to interpret experimental data in the context of a genome-scale model.
Opioid modulation of GABA release in the rat inferior colliculus
Authors: Tongjaroenbungam Walaiporn , Jongkamonwiwat Nopporn , Cunningham Joanna , Phansuwan-Pujito Pansiri , Dodson Hilary C , Forge Andrew , Govitrapong Piyarat , Casalotti Stefano O 
Published: September 2004

Abstract
Background
The inferior colliculus, which receives almost all ascending and descending auditory signals, plays a crucial role in the processing of auditory information. While the majority of the recorded activities in the inferior colliculus are attributed to GABAergic and glutamatergic signalling, other neurotransmitter systems are expressed in this brain area including opiate peptides and their receptors which may play a modulatory role in neuronal communication.

Results
Using a perfusion protocol we demonstrate that morphine can inhibit KCl-induced release of [3H]GABA from rat inferior colliculus slices. DAMGO ([D-Ala(2), N-Me-Phe(4), Gly(5)-ol]-enkephalin) but not DADLE ([D-Ala2, D-Leu5]-enkephalin or U69593 has the same effect as morphine indicating that μ rather than δ or κ opioid receptors mediate this action. [3H]GABA release was diminished by 16%, and this was not altered by the protein kinase C inhibitor bisindolylmaleimide I. Immunostaining of inferior colliculus cryosections shows extensive staining for glutamic acid decarboxylase, more limited staining for μ opiate receptors and relatively few neurons co-stained for both proteins.

Conclusion
The results suggest that μ-opioid receptor ligands can modify neurotransmitter release in a sub population of GABAergic neurons of the inferior colliculus. This could have important physiological implications in the processing of hearing information and/or other functions attributed to the inferior colliculus such as audiogenic seizures and aversive behaviour.
Is remission of depressive symptoms in primary care a realistic goal? A meta-analysis
Authors: Dawson Marliese Y , Michalak Erin E , Waraich Paul , Anderson J Ellen , Lam Raymond W 
Published: September 2004

Abstract
Background
A primary goal of acute treatment for depression is clinical remission of symptoms. Most meta-analyses of remission rates involve randomized controlled trials (RCTs) using patients from psychiatric settings, but most depressed patients are treated in primary care. The goal of this study was to determine remission rates obtained in RCTs of treatment interventions for Major Depressive Disorder (MDD) conducted in primary care settings.

Methods
Potentially relevant studies were identified using computerized and manual search strategies up to May 2003. Criteria for inclusion included published RCTs with a clear definition of remission using established outcome measures.

Results
A total of 13 studies (N = 3202 patients) meeting inclusion criteria were identified. Overall remission rates for active interventions ranged between 50% and 67%, compared to 32% for pill placebo conditions and 35% for usual care conditions.

Conclusions
Remission rates in primary care studies of depression are at least as high as for those in psychiatric settings. It is a realistic goal for family physicians to target remission of symptoms as an optimal outcome for treatment of depression.