bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aptitud clínica posterior a un pase de visita médica estructurado en comparación con un pase de visita cotidiano en médicos residentes
Authors: Olvera Acevedo Arturo , Uribe Ravell Jorge Augusto , Ángeles Garay Ulises , Carrillo González Ana Laura 
Published: February 2024

Introducción y objetivo: La aptitud clínica se entiende como el mayor o menor dominio del médico para identificar situaciones de complejidad variable, discriminar y optar entre alternativas de interpretación, acción o decisión.El pase de visita médica es la principal actividad educativa para la formación del médico.El objetivo fue demostrar la superioridad de un pase de visita médica estructurado en el desarrollo de aptitudes clínicas en residentes de medicina interna en comparación con un pase de visita médica habitual.
Método: Se realizó en residentes de medicina interna, creando dos grupos, con los residentes del grupo experimental se efectuó el pase de visita estructurado y problematizado y con los del grupo control el pase de visita médica habitual.Al término de la intervención se aplicó un cuestionario validado en el que se abordaron 7 indicadores de aptitud clínica.La escala de aptitud clínica fue estimada mediante la prueba de Pérez Padilla y Viniegra. Para la comparación de medias y de medianas del puntaje de los indicadores entre los grupos de estudio, se utilizó prueba de normalidad de Shapiro Wilk, t de Student y U de Mann and Whitney.
Resultados: En cuanto a los indicadores de aptitud clínica, la puntuación para indicación de auxiliares diagnósticos fue de 12.3 ± 0.96 para el grupo experimental y de 11 ± 0.82 para el grupo control, p = 0.094; para la integración diagnóstica, la media fue de 14.3 ± 0.96 para el grupo experimental y de 12.3 ± 1.71 para el grupo control, p = 0.087. Para las acciones terapéuticas, la media fue de 13.3 ± 1.26 para el grupo experimental y media 11.3 ± 1 para el control, p 0.62; para la indicación de procedimientos invasivos, media 10 ± 1.41 (mediana 9.5) y 9.5 ± 0.59 (mediana 9.5) para los controles, p = 0.75. Con respecto a la identificación de factores de riesgo, la media fue de 11 ± 1.41 en el grupo experimental y de 11.5 ± 1.29 para los controles, p = 0.336; para la iatrogenia por omisión, de 11.3 ± 1.71 y de 7.5 ± 1.29, p = 0.032, y para la iatrogenia por comisión, de 11.8 ± 0.96 (mediana 11.5) y de 8.5 ± 0.58 (mediana 8.5), p = 0.019, respectivamente.
Conclusiones. El pase de visita médica estructurado y problematizado tiene efecto más positivo en el desarrollo de aptitudes clínicas en residentes de medicina interna para la atención de Lupus Eritematoso Sistémico (LES).
Complex analysis of the geodynamic conditions of the Absheron-Balkhan oil and gas zone
Authors: Sadigova Gunel , Zamanova Aynur , Hasanov Amin 
Published: February 2024

The Absheron-Balkhan oil and gas area is located in the contact zone of the Scythian-Turanian platform with the South Caspian basin (SCB). In recent years, in addition to theoretical considerations, scientists have conducted a number of geophysical studies to determine the structure of sediment cover in the South Caspian Basin. The information obtained about the depth structure has formed a new idea about the formation of the South Caspian basin. The purpose of the work is to study the features of geodynamics of the zone of the junction of the South Caspian basin and the Scythian-Turanian epi-Hercynian platform. The research methodology combines a complex analysis of geological, seismological, geomorphological, and geodetic data on the studied area. Geological and geophysical data in particular on regional profiles were used to link earthquakes to specific geological structures.
The South Caspian Basin is surrounded by active mountain zones on all sides. The Kopeh Dagh, Alborz, and Talysh mountains, which connect the eastern, southern, and western sides of the basin, are observed with earthquakes not deeper than 30 km. In contrast, earthquakes were observed in the Absheron-Balkhan threshold, which covers the northern part of the basin, at depths greater than 30 km. Tectonically, the Absheron-Balkhan threshold is located at the junction of the South Caspian oceanic crust and the epi-Hercynian Scythian- Turanian continental crust.
Seismic events, mainly in the northern part of the South Caspian Basin are necessary to study the geodynamic conditions of this area, and to determine the causes of earthquakes. It was observed that the strongest and deepest earthquakes, as well as tectonic processes, occurred in the northern flank of the South Caspian Basin, in the Absheron-Balkhan fold zone, and in the pre-platform area. Analysis of the focal mechanisms and depths of earthquakes proves that they are not specific to collision structures. The high seismic activity of the study area, the observation of crustal deformations at the edges of the basin (based on GPS data), and the development of mud volcanism indicate that the geodynamic conditions of the basin are active. Analysis of the seismic events data shows that the subduction of the oceanic crust of the SCB in the zone of the Absheron threshold under the continental crust of the Scythian- Turanian is the main geological event that caused seismic activity in modern times.
KEYWORDS: Absheron-Balkhan fold zone, geodynamic conditions, South Caspian Basin, earthquake, deep structure.
Clinicopathological profile of multiple myeloma at a tertiary care hospital in a resource-poor setting: A retrospective study
Authors: Biswal Prapannajeet , Pandey Raghvendra Deo , Singh Gurmeet 
Published: February 2024

Objectives:
The objective of this study was to study the clinicopathological profile of multiple myeloma (MM) presenting to Jawaharlal Nehru Hospital and Research Center (JLNH&RC) Bhilai and document the disease in central India.

Material and Methods:
This was a retrospective observational study using patient data from January 2013 to December 2019. The clinical and radiological findings, laboratory parameters, and bone marrow examination were analyzed.

Results:
About 35.38% of patients presented in the 6th decade of life with a male-to-female ratio of 1.3:1. About 91.93% of patients had low backache and bone pain, and 96.92% of patients had Anemia. About 63.01% of patients had serum creatinine >2 mg/dL, and 92.30% of patients had A/G ratio reversal. About 64.70% of patients had serum beta-2 microglobulin (≥3.5 μg/mL). About 80.7% had osteolytic lesions, predominantly in the skull and pelvis. About 46.15% of patients had >50% plasma cells on bone marrow aspirate. About 85.71% exhibited hypercellularity, and 8.92% of patients had grade 2 marrow fibrosis. About 76.92% of patients presented with Durie Salmon stage III disease, and 58.82% presented with international staging system (ISS) stage II disease.

Conclusion:
MM has an inconsistent clinical presentation with multiple system involvement. It should be considered as a differential in patients above 50 years of age presenting with normocytic normochromic Anemia and bony pain. Bone marrow study is important in resource-poor settings where specialized laboratory testing is limited. The Durie and Salmon staging and the ISS can be used for the prognosis with equal efficacy.
The first results and prospects of medical genetic studies of museum and archaeological samples
Authors: Андреева Т.В. , Быданов А.С. , Гусев Ф.Е. , Рогаев Е.И. 
Published: February 2024

Несмотря на впечатляющее успехи археогенетики, медико-генетическая история древнего народонаселения остаётся мало разработанной областью. Работы по исследованию древних геномов отдельных индивидов или групп людей, живших в различные исторические и доисторические периоды, как правило, связаны с изучением их эволюционной и популяционной истории, происхождения и миграций. В обзоре мы рассматриваем перспективность нового направления – патогенетики древних людей. Для корректной медико-генетической интерпретации геномных данных необходимы критерии достоверности, учитывающие особенности древней ДНК: плохую сохранность ДНК, контаминацию современной ДНК человека и микробной ДНК и особенно химические модификации, накапливающиеся в ДНК. Такие модификации ведут к появлению с высокой частотой так называемых “постмортальных” мутаций в древних геномах. К настоящему времени есть лишь единичные работы, посвященные выявлению генов менделирующих заболеваний при анализе древней ДНК, которые будут рассмотрены в обзоре.
Despite the impressive achievements of paleogenetics, the medical and genetic history of ancient populations has yet to be explored in detail. The vast majority of studies on ancient individuals or groups of people who lived in various historical and prehistoric periods focus on their evolutionary and population history, their origin and migrations. Here we discuss the prospects of a new direction – the pathogenetics of ancient people. For correct medical and genetic interpretation of genomic data, reliability criteria have to be established taking into account the specific features of ancient DNA: poor DNA preservation, contamination with modern human and microbial DNA, and, especially, chemical modifications accumulating in DNA. In the sequencing data of ancient genomes these modifications manifest themselves with high frequency in a form of so-called “postmortem” mutations. To date, only a few studies are devoted to the identification of genes of mendelian diseases using ancient DNA, which are discussed in this review.
Development of a universal STR panel for PGT-M for cystic fibrosis, taking into account the specific haplotype of chromosomes carrying the CFTR F508del variant
Authors: Соловьёва Е.В. , Склеймова М.М. , Минайчева Л.И. , Агафонова А.А. , Петрова В.В. , Скрябин Н.А. 
Published: February 2024

Введение. Преимплантационное генетическое тестирование (ПГТ) развивается как вариант ранней дородовой профилактики наследственных заболеваний. Таргетный вариант ПГТ моногенного заболевания (ПГТ-М) предусматривает сочетание анализа патогенного генетического варианта и косвенных ДНК-маркеров. Перечень сцепленных с геном CFTR ДНК-маркеров для целей ПГТ муковисцидоза (МВ) варьирует у разных авторов. Цель: разработка панели STR-маркеров для ПГТ МВ. Методы. С использованием данных литературы, баз данных выбраны внутригенные и внегенные STR-маркеры, сцепленные с геном CFTR. Панель маркеров протестирована на образцах ДНК семи семей с МВ, в которых заболевание обусловлено патогенным вариантом F508del. Только в одной семье второй мутацией была CFTRdele2,3(21kb). Для тестирования применяли методы ПЦР и фрагментного анализа на генетическом анализаторе. Результаты. Подобрана панель из 15 основных и 4 дополнительных STR-маркеров. Основная панель STR была достаточно информативна для большинства образцов родителей – носителей патогенного варианта гена CFTR. Дополнительная панель потребовалась в связи с тем, что в одном из изученных образцов наблюдалась низкая информативность по косвенным маркерам вследствие особого гаплотипа, выявленного у одного из обследованных. Заключение. Разработанная нами панель, учитывающая специфический F508del – гаплотип, может служить основой ПГТ МВ.
Background. Preimplantation genetic testing (PGT) is developing as a variant of early prenatal prevention of hereditary diseases. Targeted variant PGT for monogenic disease (PGT-M) involves a combination of pathogenic variant and indirect DNA markers analysis. The list of DNA markers linked to the CFTR gene for the purposes of cystic fibrosis PGT (PGT CF) varies by different authors. Aim: development of a panel of STR-markers for PGT CF. Methods Intragenic and extragenic STR markers linked to the CFTR gene were selected using scientific literature data and databases. The panel of markers was tested on DNA samples from seven families with CF, in which the disease is caused by the pathogenic F508del variant. Only one family had CFTRdele2,3(21kb) as the second mutation. For testing, PCR and fragment analysis methods were used. Results. 15 main and 4 additional STR markers have been selected for a panel. Most of the samples of the parents carrying the pathogenic variant of the CFTR gene confirmed the sufficient information content of the main STR panel. An additional panel was required due to the fact that one of the studied samples revealed low information rate for linked markers because of a special haplotype of the chromosome carrying the normal allele. Conclusions. The developed panel, taking into account the specific F508del haplotype, can serve as a basis for PGT CF.
Identifikasi Gaya Art Deco Dalam Arsitektur Kolonial Kota Malang Sebagai Dasar Perancangan Gedung Perpustakaan Digital
Authors: Adziim Fajar Fatkhul , Rolalisasi Andarita , Bintarjo Benny 
Published: February 2024

AbstrakKota Malang merupakan kota terbesar kedua di jawa timur setelah kota Surabaya, hal ini tidak terlepas dari efek dibukanya jalur kereta api Surabaya – Malang pada tahun 1878. Lalu ditahun 1903, Belanda memberlakukan UU Desentralisasi yang membuat kota Malang resmi menjadi Kotamadya pada tanggal 1 April 1914. Dalam upaya mengembangkan kota, Pemerintah kotamadya Malang langsung menunjuk Thomas Karsten seorang arsitek dari Belanda untuk merancang tata kota Malang, Dari tahun 1917 sampai 1929, rencana ini dilaksanakan se (Mulyadi, Witjaksono, & Fathony, 2020)cara bertahap dari bouwplan I sampai bouwplan VIII. perkembangan arsitekturnya tidak terlepas dari pengaruh luas arsitektur kontemporer, yang pada saat itu di eropa berkembang dengan pesat bangunan bergaya Art Deco. Setelah sekian lama negara Indonesia merdeka, Ciri bangunan berkonsep Art Deco masih dapat dijumpai di sejumlah bangunan peninggalan kolonial, khususnya di kota Malang hingga saat ini. Kawasan heritage Kayutangan dijadikan oleh pemerintah kota sebagai kawasan wisata sejarah dengan berbagai bentuk bangunan yang dijadikan sajian utamanya. Penelitian ini bertujuan untuk mengidentifikasi karakteristik dari bangunan-bangunan peninggalan Belanda, khususnya dikota Malang, guna dijadikannya acuan penulis untuk menarik benang merah desain yang dapat diaplikasikan kedalam perancangan gedung perpustakaan digital kota Malang.
Suicidal Risk in People with Obsessive Compulsive Disorder
Authors: Annisa Wardha Novia , Nabil Athalita Andhera , Wibisana I Komang Gede Andhika , Smith Sima , Amalia Emmy 
Published: February 2024

Obsessive compulsive disorder or Obsessive Compulsive Disorder (OCD) is a psychiatric disorder characterized by excessive anxiety, persistent thoughts (obsessions), and repetitive behaviors (compulsions). The prevalence of OCD in Europe ranges from 0.1-2.3% annually and more common in adults. The risk of suicide increases ten times more in OCD sufferers compared to the non-OCD sufferers with prevalence the OCD sufferers who has thoughts of suicide is 23.3%. This literature review aims to determine the risk factors for suicide in OCD patients so that prevention can be carried out in individuals who have risk factors. In this literature review we conducted a search on the PubMed, Google Schoolar, and Researchgate database using the search keyword “Obsessive Compulsive Disorder”, “Obsessive Compulsive Symptoms”, “Suicide”, “Self-murder”, and “Risk Factor”. OCD is a disease with genetic and non-genetic risk factors, can manifest clinically as obsessions and compulsions that occur due to failure in responding to yedasantience signals so that the security motivation system (SMS) will be activated longer than normal. The longer SMS activated, the more depressive symptoms can develop, which tends to give rise to suicidal thoughts. In conclusion, risk factors for suicide in OCD that can be identified earlier will not only help the patient's prognosis but also help them choose treatment steps that are appropriate with the severity of the OCD symptoms.
Optimasi Parameter Pemesinan Ulir Material Titanium Ti-6al-4v Eli Terhadap Jarak Pitch dan Sudut Ulir Menggunakan Metode Taguchi
Authors: Akhyar Gusri , Septiani Cici , Hamni Arinal , Burhanuddin Yanuar , Harun Suryadiwansa , Kusnadi Andi 
Published: February 2024

Paduan titanium merupakan salah satu material ringan yang banyak digunakan karena memiliki sifat yang ringan dan tahan terhadap korosi. Hal ini menunjukan bahwa pembuatan ulir pada titanium sangat mendukung untuk diaplikasikan pada bidang biomedis. Kepresisian geometri ulir akan memberikan pengaruh terhadap kwalitas ulir terutama pada saat ulir bekerja bila sudah digunakan sebagai penyambung tulang. Kesalahan geometri ulir titanium pada pemesinan bubut ulir dipengaruhi oleh kecepatan potong, kedalaman potong, dan jenis pemesinan. Penelitian ini meneliti respon kesalahan pitch,dan kesalahan sudut ulir pada diameter ulir M4x0.7 dengan 3 level dan 3 faktor lalu pengolahan datanya menggunakan proses optimasi Taguchi dengan variasi kecepatan potong sebesar 17.58, 21.35, 25.12 m/min, kedalaman potong sebesar 0.085, 0.108, dan 0.143 mm, serta pemesinan bubut yang digunakan yaitu pemesinan kering, menggunakan pelumas minyak sawit dan menggunakan pelumas minyak sintetik. Hasil optimal didapatkan pada kombinasi kondisi pemotongan dengan factor kecepatan potong 25.12 m/min dan kedalaman potong 0.108 mm serta pelumas kelapa sawit dimana respon kesalahan pitch 0.170 mm dan Kondisi pemotongan optimal pada kesalahan sudut ulir yaitu pada parameter kecepatan potong 17.58 m/min kedalaman potong 0.085 mm dan jenis pemesinan kering dimana respon kesalahan sudut 0.260°.
Pengaruh Personality Psychopathy dan Narcissism Terhadap Radikalisme
Authors: Nawang Retno Dwiningrum  , Zulkarnain Zulkarnain 
Published: February 2024

Pengaruh dark personality psychopathy dan narcissism tampaknya masih belum diteliti komprehensif dalam kajian radikalisme dan terorisme. Beberapa hasil penelitian terbaru mengungkapkan bahwa sangat penting menganalisis dan melihat radikalisme dengan dark personality psychopathy dan narcissism. Penelitian ini bertujuan untuk mengetahui pengaruh psychopathy dan narcissism terhadap radikalisme. Data dikumpulkan secara acak melalui kuesioner Online diisi oleh 469 mahasiswa Perguruan Tinggi di Kota Balikpapan untuk menguji pengaruh langsung dark personality psychopathy dan narcissism terhadap radikalisme. Hasilnya penelitian ini mengungkapkan dark personality psychopathy berpengaruh langsung terhadap sikap radikalisme. Sedangkan dark personality psychopathy Narcissism tidak berpengaruh terhadap radikalisme sedangkan, dark Personality psychopathy berpengaruh terhadap radikalisme. Temuan penelitian ini menunjukkan bahwa dark personality psychopathy dan narcissism memiliki pengaruh langsung dan tidak langsung terhadap radikalisme. Temuan penelitian dibahas dan didiskusikan dengan implikasi mempertimbangkan faktor kepribadian dalam kajian radikalisme dan terorisme.
Minimizing Total Completion Time, Total Earliness Time, and Maximum Tardiness for a Single Machine scheduling problem
Authors: Kalaf Bayda Atiya , Nagham Muosa Neamah  , Khalifa Hamiden Abd El-Wahed 
Published: February 2024

Machine scheduling problems (MSP) are considered as one of the most important classes of combinatorial optimization problems. In this paper, the problem of job scheduling on a single machine is studied to minimize the multiobjective and multiobjective objective function. This objective function is: total completion time, total lead time and maximum tardiness time, respectively, which are formulated as are formulated. In this study, a mathematical model is created to solve the research problem. This problem can be divided into several sub-problems and simple algorithms have been found to find the solutions to these sub-problems and compare them with efficient solutions. For this problem, some rules that provide efficient solutions have been proved and some special cases have been introduced and proved since the problem is an NP-hard problem to find some efficient solutions that are efficient for the discussed problem 1// and good or optimal solutions for the multi-objective functions 1// ,, and emphasize the importance of the dominance rule (DR), which can be applied to this problem to improve efficient solutions.
First Record of Phoretic Mite from Red Palm Weevil Rhynchophorus ferrugiuneus (Olivier,1790) from Basrah, Southern Iraq
Authors: Abdullah Najim Shurooq , Hussain Ali Jabbar  , Basil Yousuf Mahdi  
Published: February 2024

The red palm weevil Rhynchophorus ferrugineus (Olivier, 1790), which belongs to the family Curculionidae, order Coleoptera, is one of the most important palm pests, which leads to heavy losses in date palms. In the last few years, it has been recorded in Iraq, from Safwan city south of Iraq, where it was detected on date palm trees (Phoenix dactylifera L, Arecales: Arecaceae). In the current study, specimens of adult weevils were collected from infested date palms (Phoenix dactylifera), that showed signs of infection in Safwan district, south of Basra province. The results of the investigation showed the presence of phoretic mites associated with the red palm weevil Rhynchophorus ferrugineus (Olivier, 1790). Two genera of Uropodid mites, deutonymph, were attached by anal pedicel to body parts of adult red palm weevils. They were collected and identified as Centrouropoda (Uropodidae), and Uroovbovella (Urodinychidae), according to accurate taxonomic keys. The differentiation between two genera of mites was studied. The deutonymphs were examined and photographed by an AM Scop camera installed on a light microscope, and the insects were photographed by a LEICA microscope. The infestation symptoms were illustrated with pictures.
Determining of Efficiency For The N749 Dye contact with TiO2 In Dye Sensitized Solar Cell
Authors: Nahi Naeam , Hadi J. M. Al-Agealy  , Hossain Milani Moghaddam  
Published: February 2024

In this research, we investigate and evaluate the efficiency of a hetero junction N749- device based on a simple donor-acceptor model for electron transfer. Electron transfer from a photo-excited N749 sensitized into a wide-band gap is the basic charge separation in dye-sensitized solar cells, or "DSSCs". Due to the understanding of the current of the DSSCs functioning mechanism, the energy levels of the hetero junction N749- device surrounded by DCM solvent as polar media must be continuum levels. The current-voltage (J-V) characteristics of the N749- device are calculated in two concentrations at room temperature (T=300 k) and 100 irradiation. The fill factor and efficiency of the device are found to be 0.134 and 6.990 for concentration compared to 0.146 and 9.974 for concentration . The efficiency of the N749- device is in agreement with experimental results. It also offers a rational for the suggestion to use the application of N749- high-performance solar cells.
Effect of alcoholic phenol and nanocapsules extract from grape seed (Vitis vinifera) on egg hatching and adult death of southern cowpea beetles
Authors: A.S. Mall Rusul , Sahar A. Kathier  
Published: February 2024

Pulses are the second most significant economic crop that have been attacked by many storage pests. One of these pests is the cowpea beetle (Callosobruchus maculatus). This study aims to study the effect of phenol grape seed (Vitis vinifera) extract (1000,1500,2000,2500and 3500 mg/L) on eggs and adults. The results showed that the alcoholic extract of the grape seed (Vitis vinifera) recorded for the egg hatching was (80, 56.67, 53.33, 40.00 and 10.00%) respectively, Results in the use of nanocapsules at concentrations of 100 and 500 mg/L showed the egg hatching ratio was (53.33, 16.67%) respectively, while the results of alcoholic extracts of grape seed (Vitis vinifera) recorded for adult mortality was(20.00, 70.00, 73.33, 76.67and96.67%) respectively after 72 hours of treatment , Results in the use of nanocapsules at concentrations of 100 and 500 mg/L showed the adult mortality rate was (26.67, 93.33%) respectively after 72 hours of treatment , The adult mortality rate increases by increasing the concentrations.