bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sheltering Each Other from the Storms to Come. Why We Need to Become Allies Rather Than Critics of Liberal Cultural Institutions
Authors: Bhagwati Sandeep 
Published: October 2023

AbstractThis polemic chapter reflects on strategic conundrums and blind spots in the discourses and practices of activist and academic critique of powerful liberal cultural institutions. Why do we mostly censure those who already want to listen to us? Why do we shame mainly those who can at all be shamed into reactions? Are we not neglecting possible and necessary effects of our demands for diversity, equity and inclusion when we only focus on those who already see such issues as their concern, even if they have not yet been able to implement them within their institutions? What, in turn, do we do about cultural institutions and artistic traditions in authoritarian, homo- and transphobic, misogynist, xenophobic societies—not only those in Europe and North America, but everywhere? Do we have activist strategies and cogent arguments for those contexts? And should we not stand closer with and more emphatically support our allies within the liberal cultural institutions in operating in liberal democracies.
Optimal regularity for degenerate Kolmogorov equations in non-divergence form with rough-in-time coefficients
Authors: Pagliarani Stefano , Lucertini Giacomo , Pascucci Andrea 
Published: October 2023

AbstractWe consider a class of degenerate equations in non-divergence form satisfying a parabolic Hörmander condition, with coefficients that are measurable in time and Hölder continuous in the space variables. By utilizing a generalized notion of strong solution, we establish the existence of a fundamental solution and its optimal Hölder regularity, as well as Gaussian estimates. These results are key to study the backward Kolmogorov equations associated to a class of Langevin diffusions.
Intrinsic sub-Laplacian for hypersurface in a contact sub-Riemannian manifold
Authors: Barilari Davide , Habermann Karen 
Published: October 2023

AbstractWe construct and study the intrinsic sub-Laplacian, defined outside the set of characteristic points, for a smooth hypersurface embedded in a contact sub-Riemannian manifold. We prove that, away from characteristic points, the intrinsic sub-Laplacian arises as the limit of Laplace–Beltrami operators built by means of Riemannian approximations to the sub-Riemannian structure using the Reeb vector field. We carefully analyse three families of model cases for this setting obtained by considering canonical hypersurfaces embedded in model spaces for contact sub-Riemannian manifolds. In these model cases, we show that the intrinsic sub-Laplacian is stochastically complete and in particular, that the stochastic process induced by the intrinsic sub-Laplacian almost surely does not hit characteristic points.
Dermatitis herpetiformis und sonstige Formen der Weizensensitivität
Authors: Malkovics T. , Joura M. I. , Koszorú K. , Sárdy M. 
Published: October 2023

Zusammenfassung
Hintergrund
Die Weizensensitivität ist ein Sammelbegriff für mehrere, v. a. gastrointestinale Erkrankungen, die im Rahmen einer Überempfindlichkeitsreaktion nach Weizenverzehr auftreten. Die meistens Reizdarmsyndrom-ähnlichen Symptome werden oft von Hautveränderungen begleitet. Die Weizensensitivität umfasst neben der Zöliakie und der Dermatitis herpetiformis (die bullöse kutane Manifestation der Zöliakie) auch die Nicht-Zöliakie-Glutensensitivität (NCGS), die allergische Nickel-Kontaktmukositis, die Weizenallergie, die Amylase-Trypsin-Inhibitor-Intoleranz sowie die FODMAP(fermentierbare Oligosaccharide, Disaccharide, Monosaccharide und Polyole)-Intoleranz.

Ziel der Arbeit
Der Beitrag soll eine Übersicht über die klinischen, insbesondere dermatologischen und gastrointestinalen Eigenschaften der unterschiedlichen Weizensensitivitätsformen geben. Zudem werden die Diagnostik sowie mögliche Therapieformen erörtert.

Material und Methoden
Es erfolgte eine selektive Literaturrecherche mit Evaluierung von durch die Autoren selbst erhobenen klinischen Daten.

Ergebnisse
Die Hautveränderungen sind bei der Dermatitis herpetiformis sehr krankheitsspezifisch. Bei der Weizenallergie treten jedoch häufig Symptome auf, die auch für andere Erkrankungen typisch sind. Sonstige Formen der Weizensensitivität manifestieren sich primär mit gastrointestinalen Auffälligkeiten, aber auch extraintestinale Symptome kommen vor. Die Diagnostik ist oft komplex und bedarf disziplinübergreifender Zusammenarbeit mit Gastroenterologen. Die Therapie besteht aus einer weizen- bzw. glutenfreien Diät.

Diskussion
Die Kenntnis unterschiedlicher und häufig auftretender dermatologischer Anzeichen einer Weizensensitivität ist von großer Bedeutung, da diese immer öfter im Zusammenhang mit einer gastrointestinalen Pathologie, Intoleranzreaktionen und Allergien diagnostiziert werden.
Mono- and multimeric PSMA-targeting small molecule-thorium-227 conjugates for optimized efficacy and biodistribution in preclinical models
Authors: Böhnke Niels , Indrevoll Bård , Hammer Stefanie , Papple Alex , Kristian Alexander , Briem Hans , Celik Arif , Mumberg Dominik , Cuthbertson Alan , Zitzmann-Kolbe Sabine 
Published: October 2023

Abstract
Purpose
PSMA (prostate-specific membrane antigen) is highly expressed on prostate cancer (PrCa) cells and extensively used as a homing target for PrCa treatment. Most prominently, PSMA-targeting conjugate PSMA-617, carrying a DOTA chelator and labeled with therapeutic radionuclides like beta-emitting lutetium-177 or alpha-emitting actinium-225, has shown clinical activity in PrCa patients. We sought to develop PSMA-targeting small molecule (SMOL) conjugates that show high uptake in PSMA-expressing tumors and fast clearance, and can easily be labeled with the alpha emitter thorium-227 (half-life 18.7 days).

Methods
A novel linker motif with improved competition against 3H-PSMA-617 on PSMA-expressing LNCaP cells was identified. A 2,3-hydroxypyridinone chelator modified with carboxyl groups (carboxy-HOPO) with increased hydrophilicity and robust labeling with thorium-227 was developed and allowed the synthesis of mono-, di-, tri-, and tetrameric conjugates. The resulting monomeric and multimeric PSMA SMOL-TTCs (targeted thorium conjugate) were evaluated for cellular binding, internalization, and antiproliferative activity. The in vivo antitumor efficacy of the PSMA SMOL-TTCs was determined in ST1273 and KUCaP-1 PrCa models in mice, and their biodistribution was assessed in cynomolgus monkeys, minipigs, and mice.

Results
The monomeric and multimeric PSMA SMOL conjugates were readily labeled with thorium-227 at room temperature and possessed high stability and good binding, internalization, and antiproliferative activity in vitro. In vivo, the monomeric, dimeric, and trimeric PSMA SMOL-TTCs showed fast clearance, potent antitumor efficacy, and high uptake and retention in prostate tumors in mice. No major uptake or retention in other organs was observed beyond kidneys. Low uptake of free thorium-227 into bone confirmed high complex stability in vivo. Salivary gland uptake remained inconclusive as mini pigs were devalidated as a relevant model and imaging controls failed in cynomolgus monkeys.

Conclusion
Monomeric and multimeric PSMA SMOL-TTCs show high tumor uptake and fast clearance in preclinical models and warrant further therapeutic exploration.
Vaginal microflora following the use of a disposable home-use vaginal device and a commercially available ring pessary for pelvic organ prolapse management: a randomized controlled trial
Authors: Ziv Elan , Keller Nathan , Erlich Tsvia 
Published: October 2023

Abstract
Purpose
To investigate whether ProVate, a novel, disposable, self-inserted vaginal device for pelvic organ prolapse management, clinically affects the vaginal microflora, as compared with a commercially available ring pessary, to assess its microbiological safety.

Methods
This interventional, prospective, multi-center, open-label, randomized, controlled, statistically powered (noninferiority), home-use, crossover study was conducted at seven sites. Participants were randomized into either group A (using ProVate and then a new reusable commercially available ring pessary [control]) or B (using control device and then ProVate) with a 1:1 ratio. Noninferiority of ProVate over the control was evaluated for the primary endpoint, which was based on meeting one of the failure criteria: significant change in Lactobacillus spp., Gardnerella vaginalis, Candida morphotypes, or Staphylococcus aureus levels compared to the baseline (significant change: Nugent score ≥ 7 or > 1 scale unit increase in S. aureus or Candida morphotype), bothersome vaginal infection symptoms, or symptoms requiring treatment for infection.

Results
The study included 58 participants (mean age: 64.5 years, 91.4% postmenopausal). There were no significant microfloral changes in terms of the four microorganisms mentioned above, the rate of Nugent score ≥ 7 after use was low and comparable between the two devices, and the rate of patients with a > 1 unit-scale change (increase or decrease) from the baseline to the end-of-use phase in any studied microorganism was comparable between the devices. The failure rate was 15.5% for ProVate and 15.5% for control while using 383 ProVate devices over 1647 days or one control device throughout the study. Two patients had bothersome vaginal complaints and one had overt vaginal infection in the control group, but no such cases were observed in the ProVate group.

Conclusion
The primary endpoint of possible vaginal microbial changes, bothersome vaginal symptoms, or treatment-requiring vaginal complaints while using ProVate was successfully met. Our findings show that the vaginal microflora is comparable when using either ProVate or commercially available ring pessary (control) with a relatively low rate of vaginal infections.
Trial registration details: ClinicalTrials.gov; URL: https://www.clinicaltrials.gov/ct2/show/NCT03345121?term=NCT03345121&draw=2&rank=1; No. NCT03345121; Registration date, November 17, 2017; initial enrollment started on August 20, 2017.
Assessment of skin pigmentation-related bias in pulse oximetry readings among adults
Authors: Khanna Ashish K. , Beard John , Lamminmäki Sakari , Närväinen Johanna , Antaki Nicholas , Yapici Halit O. 
Published: October 2023

Abstract
Purpose
Recent reports that pulse oximeters may overestimate oxygen saturation in individuals with darker skin pigmentation have prompted concerns from regulatory authorities regarding racial bias. We investigated the performance of TruSignal SpO2 sensors (GE Healthcare, Helsinki, Finland) in adults with varying skin pigmentation.

Methods
A retrospective study was conducted using a set of pooled assessments of SpO2/SaO2 measurements from nine studies to assess bias, accuracy (Arms), and precision of TruSignal sensors in healthy adults under induced hypoxia. Subgroup analyses were performed based on oxygen saturation levels (band 1, ≥ 70 and ≤ 80%; band 2, > 80 and ≤ 90%; band 3, > 90 and ≤ 100%).

Results
Of the 10,800 data points from 131 individuals, 8,202 (75.9%) and 2,598 (24.1%) were assigned to the light and dark pigment groups, respectively. Bias was 0.14% overall and less than 1% across oxygenation bands. The difference in bias between dark and light pigment groups was statistically significant at the low oxygenation band with SpO2 ≥ 70 and ≤ 80% (+ 0.58% and + 0.30% respectively; p = 0.0035). Throughout the saturation range, Arms was 1.64% in the light and 1.71% in the dark pigment group, within device specifications and regulatory requirements. Oxygenation was the dominating factor in stepwise ANOVA modeling. The mixed model also showed that bias was strongly affected by the oxygenation range.

Conclusion
TruSignal sensors demonstrated higher bias at lower oxygen saturation, with less than 0.5% difference between pigment groups. These findings raise new questions, such as ways to improve pulse oximetry measurements during challenging clinical conditions, including low perfusion.
On the Two-Point Function of the Ising Model with Infinite-Range Interactions
Authors: Aoun Yacine , Khettabi Kamil 
Published: October 2023

AbstractIn this article, we prove some results concerning the truncated two-point function of the infinite-range Ising model above and below the critical temperature. More precisely, if the coupling constants are of the form $$J_{x}=\psi (x)\textsf{e}^{-\rho (x)}$$

J
x

=
ψ

(
x
)

e

-
ρ
(
x
)

with $$\rho $$
ρ
some norm and $$\psi $$
ψ
an subexponential correction, we show under appropriate assumptions that given $$s\in \mathbb {S}^{d-1}$$

s
∈

S

d
-
1

, the Laplace transform of the two-point function in the direction s is infinite for $$\beta =\beta _\textrm{sat}(s)$$

β
=

β
sat

(
s
)

(where $$\beta _\textrm{sat}(s)$$

β
sat

(
s
)

is a the biggest value such that the inverse correlation length $$\nu _{\beta }(s)$$

ν
β

(
s
)

associated to the truncated two-point function is equal to $$\rho (s)$$

ρ
(
s
)

on $$[0,\beta _\textrm{sat}(s)))$$

[
0
,

β
sat

(
s
)

)
)

. Moreover, we prove that the two-point function satisfies up-to-constants Ornstein-Zernike asymptotics for $$\beta =\beta _\textrm{sat}(s)$$

β
=

β
sat

(
s
)

on $$\mathbb {Z}$$
Z
. As far as we know, this constitutes the first result on the behaviour of the two-point function at $$\beta _\textrm{sat}(s)$$

β
sat

(
s
)

. Finally, we show that there exists $$\beta _{0}$$

β
0

such that for every $$\beta >\beta _{0}$$

β
>

β
0

, $$\nu _{\beta }(s)=\rho (s)$$

ν
β

(
s
)

=
ρ

(
s
)

. All the results are new and their proofs are built on different results and ideas developed in Duminil-Copin and Tassion (Commun Math Phys 359(2):821–822, 2018) and Aoun et al. in (Commun Math Phys 386:433–467, 2021).
Mathematics self-concept moderates the relation between cognitive functions and mathematical skills in primary school children
Authors: Passiatore Ylenia , Costa Sara , Grossi Giuseppe , Carrus Giuseppe , Pirchio Sabine 
Published: October 2023

AbstractIn this paper, we investigated the contribution of both cognitive and affective factors to mathematical skills. In particular, we looked at the protective role of self-concept for mathematical learning and performance. In a field study, we tested the relation of math self-concept and short-term visuo-spatial working memory to the mathematical abilities of second- grade primary school children in Italy (N = 105). Measures included the “Test for the evaluation of calculating and problem-solving abilities” (AC-MT 6–11), the backward Corsi blocks test (Battery for Visuo-Spatial Memory), and the mathematics self-concept sub-scale of the Self-Description Questionnaire-I (SDQ-I, Italian version). As expected, correlation and moderated regression analyses showed that mathematics self-concept and working memory both positively predict mathematical operations and numeracy, but not accuracy. Simple slope analysis confirmed our moderation hypothesis, with working memory predicting mathematical abilities at low levels of math self-concept, but not at medium and high levels. The theoretical and practical implications are discussed.
Civil Society, Neighbourhood Diversity and Deprivation in UK and Sweden
Authors: Borkowska Magda , Kawalerowicz Juta , Elgenius Gabriella , Phillimore Jenny 
Published: October 2023

AbstractThis paper explores the relationship between neighbourhood level density of civil society organisations (CSOs), diversity, and deprivation. We compare the UK and Sweden, two countries with different civil society traditions and welfare state regimes. We use data on formal civil society organisations to examine whether diverse neighbourhoods have lower levels of civil society infrastructure. In the UK, contrary to what could be expected from Putnam's assertion that diversity has a negative effect on trust, thus limiting civil society activities at the neighbourhood level, we observe a positive relationship between the density of CSOs and diversity. In Sweden, we find different patterns. First, we observe a negative correlation between CSO density and diversity. Second, we find lower density of formal CSOs in areas with high diversity and high economic disadvantage and higher density in areas characterised by low diversity and high disadvantage.
Industrial hemp (Cannabis sativa L.)—a valuable alternative crop for growing in agricultural soils contaminated with heavy metals
Authors: Flajšman Marko , Košmelj Katarina , Grčman Helena , Ačko Darja Kocjan , Zupan Marko 
Published: October 2023

AbstractHemp (Cannabis sativa L.) is a multiuse plant, which has been abundantly studied for phytoremediation purposes in recent years. The majority of experiments were performed in greenhouses with potted plants where hemp showed promising results. Only few studies tested hemp on site in heavy metal–polluted agricultural soil in real environmental conditions and practical assessments of hemp phytoremediation feasibility are lacking. We conducted a comprehensive study using 2 legal industrial hemp varieties (Futura 75 and Tisza) at three differently polluted locations (heavily polluted location, HP; moderately polluted location, MP; and slightly polluted location, SP) in the heavy metal contaminated Celje valley in Slovenia and determined the content of Pb, Zn, and Cd in 5 plant organs/tissues. The yield of each organ/tissue was determined as well to enable us to calculate the phytoremediation potential (PP). On average, plants grown in the HP location accumulated the highest values of all examined elements, followed by plants from the MP location and plants from the SP location, showing that the content of heavy metals in soil influences the accumulation in plants. Accumulation of Pb/Zn/Cd by plant organs/tissues was distributed in the following order: inflorescences (Pb-4.10/Zn-92.8/Cd-0.50 mg/kg) > seeds (Pb-1.79/Zn-92.6/Cd-0.27 mg/kg) > roots (Pb-1.15/Zn-15.0/Cd-0.44 mg/kg) > stem bark (Pb-0.42/Zn-12.4/Cd-0.23 mg/kg) > stem woody core (Pb-0.34/Zn-4.6/Cd-0.15 mg/kg). The only exception was for Cd, where roots accumulated a higher value than seed, yet lower than inflorescences. PP was calculated by multiplying hemp tissue/organ yield by the relative concentrations of heavy metal. The highest PP for Pb and Cd were achieved at the HP location (3.80 and 0.23 g/ha/vegetation period). On the other hand, tissue/organ yield was more important for high PP of Zn, where the SP location reached the highest PP for Zn (148.5 g/ha/vegetation period) due to the highest yields. Only seeds from HP and MP locations accumulated a too high content of Pb; otherwise, all other fibers and seeds can be safely used in the textile and food industry. Results of this study showed that hemp cannot be considered an efficient plant for the phytomanagement of contaminated areas. Nevertheless, hemp cultivation in heavy metal–polluted agricultural soils seems feasible since the majority of tissues/organs were not contaminated and different products can be obtained from various parts of the hemp plant.
Loneliness and Perceived Social Support in Endometriosis: The Roles of Body Image Disturbance and Anticipated Stigma
Authors: Calvi Catherine , Sherman Kerry A. , Pham Dione 
Published: October 2023

Abstract
Background
Research has identified that living with the chronic inflammatory disease endometriosis adversely impacts social functioning and interpersonal relationships, specifically, feelings of loneliness and a lack of perceived social support. Commonly experienced body image disturbance (BID), combined with the anticipation of endometriosis-related stigma from others, may result in further social withdrawal. This study aimed to quantitatively investigate the association between BID and social functioning (loneliness and diminished perceived social support), and the potential moderating effect of anticipated stigma on these associations.

Method
Participants (N = 212) with a self-reported endometriosis diagnosis completed an online questionnaire measuring social and emotional loneliness, perceived social support, BID, anticipated stigma and demographic and medical characteristics.

Results
Mean scores indicated high levels of BID, emotional loneliness and diminished perceived social support. Bootstrapped multivariable regression analyses indicated that BID was significantly associated with greater emotional loneliness and lower perceived social support. BID was also associated bivariately with greater social loneliness. Anticipated stigma from healthcare workers moderated the association of BID with perceived social support, such that poorer perceived support was reported when anticipated stigma was high, despite the presence of minimal BID.

Conclusion
These findings highlight the psychological challenges of living with endometriosis in terms of highly prevalent BID, in the context of feeling lonely and poorly supported. The further negative impact of anticipated stigma suggests that psychosocial interventions may benefit from additionally targeting these perceptions of stigma.
Street traders’ contribution to food security: lessons from fresh produce traders’ experiences in South Africa during Covid-19
Authors: Wegerif Marc C. A. 
Published: October 2023

AbstractStreet traders play a key role in the food system in South Africa and many other countries. Despite their importance, the operations of street traders are not well understood and often undermined by policy makers and planners. This article provides insights into the role of street traders who sell food, in particular fresh produce, and the nature of their operations. It shares experiences of street traders in South Africa since the beginning of the Covid-19 pandemic and derives lessons from this for their contribution to food and nutrition security. The article is based on in-depth research carried out with street traders and other food system actors that they are linked to in three provinces (Gauteng, KwaZulu Natal and Limpopo) of South Africa. It was found that the street traders were severely affected during the first hard lockdown and continued to suffer due to the drop in aggregate demand that has resulted from the reduced incomes of many of their clients. They have also not been able to access the government Covid-19 recovery funds. Despite these challenges, street traders have continued to perform an even more essential role in making fresh produce accessible. This is in contrast to supermarkets that have maintained higher prices and profit margins despite the state of disaster affecting people’s ability to buy. Street traders are deserving of greater recognition and support as they play a key role in achieving food security and addressing other socio-economic challenges. Improving the conditions for street traders requires securing more public space for food trading and recognising and building on the ways that street traders use space and organise their economic lives.