bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors predicting technical failure of endoscopic transpapillary gallbladder drainage for acute cholecystitis
Authors: Hirakawa Noriyuki , Yamamoto Kenjiro , Sofuni Atsushi , Tsuchiya Takayoshi , Ishii Kentaro , Tanaka Reina , Tonozuka Ryosuke , Mukai Shuntaro , Nagai Kazumasa , Matsunami Yukitoshi , Kojima Hiroyuki , Minami Hirohito , Nakatsubo Ryosuke , Asano Kyoko , Itoi Takao 
Published: October 2023

AbstractObjectivesEndoscopic transpapillary gallbladder drainage (ETGBD) is a highly technical procedure, but few studies have evaluated factors that predict its technical success. Therefore, in this study, we sought to identify predictors of technically successful ETGBD.MethodsOne hundred and eighty‐two patients who underwent ETGBD for acute cholecystitis at our hospital were retrospectively investigated. Factors associated with technical failure were identified by focusing on clinical characteristics, anatomical features (direction of the cystic duct branch and course of the cystic duct), and procedural factors (cystic duct and gallbladder with or without contrast and cystic duct injury).ResultsThe technical success rate was 84.6% (154/182) and the clinical success rate was 96.1% (148/154). The adverse event rate was 11.0% (20/182; cystic duct injury in 13 patients, pancreatitis in six, and liver abscess in one. Univariate and multivariate analyses identified the right cranial direction and spiral‐type course of the cystic duct to be significant anatomical features and cystic duct injury to be a significant procedural feature contributing to the technical failure of ETGBD.ConclusionsETGBD is a highly practical procedure for patients with acute cholecystitis. However, difficulty is encountered in some cases because of anatomical and procedural factors. Our results suggest that ETGBD may be difficult and thus should not be performed in cases with the right cranial direction or spiral‐type course of the cystic duct or those with cystic duct injury.
Hair and plasma cortisol throughout the first 3 years of development in infant rhesus macaques, Macaca mulatta
Authors: Pritchard Alexander J. , Capitanio John P. , Del Rosso Laura , McCowan Brenda , Vandeleest Jessica J. 
Published: October 2023

AbstractCortisol expression has been demonstrated to have variation across development in rhesus macaques (Macaca mulatta). There exists contradictory evidence for the nature of this change, and age at which it occurs, across biological sample types. Consequently, we lack a cohesive understanding for cortisol concentrations across the development of a major human health translational model. We examined hair cortisol concentrations over the first 3 years of life for 49 mother‐reared infant macaques from mixed‐sex outdoor units at the California National Primate Research Center. For 48 of these subjects at infancy, 1 year, and 2 years, we obtained plasma cortisol samples for response to a stressor, adjustment to prolonged stress, and response to dexamethasone injection. Hair cortisol concentrations decreased dramatically between 3 and 10 months, followed by relative stability up to the final sampling event at around 34 months of age. Plasma cortisol showed within‐year consistency, and consistency between infancy and year 1. We document variability in the infant plasma cortisol samples, especially in percent change between samples 1 and 2. Our plasma cortisol results indicate that infants possess the physiological capacity to effectively inhibit the release of cortisol when stimulated, as effectively as later responses in juveniles. Age‐related changes in hair cortisol parallel findings indicating a large decline in the weeks following postparturation.
Monomicelle‐induced assembly route toward low‐dimensional mesoporous nanomaterials for catalysis
Authors: Zhang Wei , Zhu Kerun , Yang Chaochao , Ai Yan , Gao Yihan , Li Wei , Zhao Dongyuan 
Published: October 2023

AbstractLow‐dimensional mesoporous nanomaterials (LDMNs), which possess complementary properties in the mesoscale and nanoscale, have realized more technological potentials in a wide range of applications, in particular, catalysis. Although still in its infancy, the proposed monomicelles‐induced assembly (MIA) has been proved to be an emerging and powerful toolbox for the direct synthesis of LDMNs with well‐controlled mesostructures and architectures. This review starts from the developmental history of the MIA strategy and then discuss general protocols to fabricate the monomicelles. After that, manipulation of the monomicelles' assembly by well‐designed interfaces and confined spaces for the controllable fabrication of LDMNs are reviewed in detail. Then, catalytic applications, including thermal, photo‐ and electrocatalysis, of LDMNs are discussed critically based on the structure‐performance relationship. This review ends with a brief summary and further directions of the MIA strategy, paving the way for the synthesis of sophisticated mesoporous assemblies to achieve advanced functionalities.
Early changes in renal function during rapid up‐titration of guideline‐directed medical therapy following an admission for acute heart failure
Authors: ter Maaten Jozine M. , Mebazaa Alexandre , Davison Beth , Edwards Christopher , Adamo Marianna , Arrigo Mattia , Barros Marianela , Biegus Jan , Čelutkienė Jelena , Čerlinskaitė‐Bajorė Kamilė , Chioncel Ovidiu , Cohen‐Solal Alain , Damasceno Albertino , Diaz Rafael , Filippatos Gerasimos , Gayat Etienne , Kimmoun Antoine , Lam Carolyn S.P. , Leopold Valentine , Novosadova Maria , Pagnesi Matteo , Pang Peter S. , Ponikowski Piotr , Saidu Hadiza , Sliwa Karen , Takagi Koji , Tomasoni Daniela , Metra Marco , Cotter Gad , Voors Adriaan A. 
Published: October 2023

AimIn this subgroup analysis of STRONG‐HF, we explored the association between changes in renal function and efficacy of rapid up‐titration of guideline‐directed medical therapy (GDMT) according to a high‐intensity care (HIC) strategy.Methods and resultsIn patients randomized to the HIC arm (n = 542), renal function was assessed at baseline and during follow‐up visits. We studied the association with clinical characteristics and outcomes of a decrease in estimated glomerular filtration rate (eGFR) at week 1, defined as ≥15% decrease from baseline. Patients in the usual care group (n = 536) were seen at day 90. The treatment effect of HIC versus usual care was independent of baseline eGFR (p‐interaction = 0.4809). A decrease in eGFR within 1 week occurred in 77 (15.5%) patients and was associated with more rales on examination (p = 0.004), and a higher New York Heart Association class at the corresponding visit. Following the decrease in eGFR at 1 week, lower average optimal doses of GDMT were prescribed during follow‐up (p = 0.0210) and smaller reductions in N‐terminal pro‐B‐type natriuretic peptide occurred (geometrical mean 0.81 in no eGFR decrease vs 1.12 in GFR decrease, p = 0.0003). The rate of heart failure (HF) readmission or death at 180 days was 12.3% in no eGFR decrease versus 18.5% in eGFR decrease (p = 0.2274) and HF readmissions were 7.8% versus 16.6% (p = 0.0496).ConclusionsIn the STRONG‐HF study, HIC reduced 180‐day HF readmission or death regardless of baseline eGFR. An early decrease in eGFR during rapid up‐titration of GDMT was associated with more evidence of congestion, yet lower doses of GDMT during follow‐up.
Outlier robust inference in the instrumental variable model with applications to causal effects
Authors: Klooster Jens , Zhelonkin Mikhail 
Published: October 2023

SummaryThe Anderson‐Rubin (AR) test is an important method that allows for reliable inference in the instrumental variable model when the instruments are weak. Yet, the robustness properties of this test have not been formally studied. As it turns out that the AR test is not robust to outliers, we show how to construct an outlier robust alternative—the robust AR test. We investigate the robustness properties of the robust AR test and show that the robust AR statistic asymptotically follows a chi‐square distribution. The theoretical results are illustrated by a simulation study. Finally, we apply the robust AR test to three different case studies that are affected by different types of outliers.
Trendbericht Theoretische Chemie 2023 (3/3): Dynamik beobachten – explizite Beschreibung der Pulseigenschaften
Authors: Fasshauer Elke 
Published: October 2023

AbstractMaschinelles Lernen: Bisher zielten Anwendungen vor allem auf das Lernen von Potenzialenergiehyperflächen, derzeit zeigen sich viele neue Forschungsrichtungen. Molekülschwingungen in der Thermodynamik: Berechnung in Theorie und Simulation. Ultrakurze Laserpulse zum Beobachten molekularer Dynamik: Da die Bewegung von Elektronen genauso schnell ist wie die zeitliche Ausdehnung der Pulse, sind die Pulseigenschaften bei Simulationen explizit zu berücksichtigen.
Trendbericht Theoretische Chemie 2023 (1/3): Maschinelles Lernen jenseits von Potenzialenergiehyperflächen
Authors: Margraf Johannes 
Published: October 2023

AbstractMaschinelles Lernen: Bisher zielten Anwendungen vor allem auf das Lernen von Potenzialenergiehyperflächen, derzeit zeigen sich viele neue Forschungsrichtungen. Molekülschwingungen in der Thermodynamik: Berechnung in Theorie und Simulation. Ultrakurze Laserpulse zum Beobachten molekularer Dynamik: Da die Bewegung von Elektronen genauso schnell ist wie die zeitliche Ausdehnung der Pulse, sind die Pulseigenschaften bei Simulationen explizit zu berücksichtigen.
Lithiumbatterien mit Kunststoffelektrode
Authors: Rosenberg Dominique 
Published: October 2023

AbstractBei Lithiumbatterien könnten Kunststoffe als Anodenmaterialien die Performance verbessern. Die Idee ist dabei, einen leicht zu verarbeitenden thermoplastischen und dabei leitfähigen Kunststoff einzusetzen. In Schulen und Hochschulen lassen sich solche Batterien auf Kunststoffbasis mit einfachen Versuchsaufbauten realisieren.
Gordon Research Conference on Physical Organic Chemistry
Authors: Marten Inka , Rapp Mario , Schmidt Annika 
Published: October 2023

AbstractEnde Juni fand die Gordon Research Conference on Physical Organic Chemistry nach einer vierjährigen pandemiebedingten Pause nun erneut in der Holderness School in New Hampshire in den USA statt. Organisiert wurde die fünftägige Tagung von Burkhard König (Universität Regensburg) und Cornelia Bohne (University of Victoria); etwa 160 Teilnehmer aus aller Welt trafen sich und tauschten sich aus. Die GDCh unterstützte mit einem Reisestipendium drei Promovierende, die hier über die Konferenz berichten.
Das Wildschwein‐Paradoxon
Authors: Steinhauser Georg , Feng Bin 
Published: October 2023

AbstractWildschweine im Alpenraum sind häufig mit überdurchschnittlich viel radioaktivem Cäsium‐137 belastet. Durch neue Analytik verstehen wir, warum: Eine vielfach vergessene Quelle für radioaktives Cäsium in der Umwelt rückt wieder in den Fokus.
Weak disturbance decoupling of high‐order fully actuated nonlinear systems
Authors: Wang Na , Liu Xiaoping , Liu Cungen , Wang Huanqing 
Published: October 2023

SummaryIt is well known that all practical control systems are subject to external disturbances. Therefore, a feedback controller should be designed so that the closed‐loop system has some desired properties such as stability, good tracking performance, at the same time, the impact of external disturbances on the performance of the closed‐loop system is attenuated to some degree. On the other hand, almost all models for real fully actuated systems, which are derived based on the physical laws, are described by a set of high order differential equations. The traditional method for controlling these fully actuated systems is to convert the high order differential equations to first order differential equations, which are called the state equations, and then to design feedback controllers by using the state‐space design methods. Such conversion causes some inconveniences. To overcome such inconveniences, a high‐order fully actuated (HOFA) design method has been proposed to control HOFA systems. The main goal of this paper is to design a weak disturbance decoupling controller for HOFA nonlinear systems to guarantee the stability and desired output tracking performance of the closed‐loop system and to attenuate the impact of disturbances.
IRIS: A novel integrated instrument for co‐registered MA‐XRF mapping and VNIR‐SWIR hyperspectral imaging
Authors: Occhipinti Michele , Alberti Roberto , Parsani Tommaso , Dicorato Claudio , Tirelli Paolo , Gironda Michele , Tocchio Alessandro , Frizzi Tommaso 
Published: October 2023

AbstractThe combination of complementary techniques for materials analysis can play a key role in both art conservation and academic research. Nowadays, the correlation of x‐ray fluorescence (XRF) with hyperspectral reflectance imaging in the visible and infrared region has become a valuable tool for palette identification, painting techniques studies and for the diagnostic support dedicated to restoration and conservation. Moreover, both techniques enable researchers to reveal fascinating underpaintings, “pentimenti”, or even preparatory drawings offering new details on the creative process of the artist. This background has been a strong motivation for the development of a new multimodal tool for art and conservation: IRIS. IRIS is a mobile and reconfigurable scanner designed to address a wide range of demanding application, exploiting the opportunities given by simultaneous MA‐XRF and hyperspectral reflectance scanning in the visible‐near‐infrared (VNIR) and short‐wave‐infrared (SWIR) range from 400 to 2500 nm. The system has been designed for in‐situ, fast and non‐invasive scanning of the sample without compromising spectral resolution and high throughput performance. The scanner acquires co‐registered XRF/VNIR‐SWIR data, thus allowing the user to obtain the maximum profit from their possible correlated information: the two techniques can provide enhanced or complementary information on the same spot of analysis with minimum effort in terms of data processing and no need for spatial alignment. In the present work, the qualitative and quantitative performance of IRIS are explored, together with the presentation of in‐lab analysis on reference samples and a brief insight on a real case‐study.
Biochar from Digestate Pyrolysis as a Filler for Biopolymer Blends: Effect of Blend Composition
Authors: Infurna Giulia , Botta Luigi , Ingargiola Irene , Maniscalco Marco , Caputo Giuseppe , Dintcheva Nadka Tz. 
Published: October 2023

Abstract
This study investigates the effect of biochar (BC) as a filler for biopolymer blends, with a focus on the effect of the biopolymer weight ratio on the final BC-added blends. The blends studied in this work were obtained by varying the weight ratio of poly-butylene adipate-co-terephthalate (PBAT) and polylactic acid (PLA) due to their great importance in packaging and agricultural fields. BC has been produced in our laboratories by the slow pyrolysis of the digestate obtained from the anaerobic digestion of the organic fraction of municipal solid waste (OFMSW). After pyrolysis, digestate-derived biochar has been milled and sieved to produce a powdery form with diameter of less than 45 μm. In order to better investigate the filler/polymer interactions, biochar particles were dimensionally, morphologically and chemically characterised. The inhomogeneity of the feedstock is responsible for content and high diversity of inorganics in biochar surface. The effect of BC on PBAT and PLA biopolymer matrices is different, and for the blend compositions the relative weight ratio between PBAT and PLA plays an important role. Furthermore, the biocomposite blend has been fully characterised: rheological, morphological, mechanical and dynamic-mechanical characterisations have been carried out, highlighting how the properties results strongly influenced by the presence of BC in the blend. In addition, a study of the viscous molar mass of the two polymer matrices when processed in the presence or absence of BC particless highlighting that a strong chemical interaction occurs between PLA and BC particles, unlike PBAT and BC.

Graphical Abstract
Mapping the 12-item World Health Organization disability assessment schedule 2.0 (WHODAS 2.0) onto the assessment of quality of life (AQoL)-4D utilities
Authors: Ma Bernice Hua , Chen Gang , Badji Samia , Petrie Dennis 
Published: October 2023

Abstract
Purpose
The World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0) is a widely used disability-specific outcome measure. This study develops mapping algorithms to estimate Assessment of Quality of Life (AQoL)-4D utilities based on the WHODAS 2.0 responses to facilitate economic evaluation.

Methods
The study sample comprises people with disability or long-term conditions (n = 3376) from the 2007 Australian National Survey of Mental Health and Wellbeing. Traditional regression techniques (i.e., Ordinary Least Square regression, Robust MM regression, Generalised Linear Model and Betamix Regression) and machine learning techniques (i.e., Lasso regression, Boosted regression, Supported vector regression) were used. Five-fold internal cross-validation was performed. Model performance was assessed using a series of goodness-of-fit measures.

Results
The robust MM estimator produced the preferred mapping algorithm for the overall sample with the smallest mean absolute error in cross-validation (MAE = 0.1325). Different methods performed differently for different disability subgroups, with the subgroup with profound or severe restrictions having the highest MAE across all methods and models.

Conclusion
The developed mapping algorithm enables cost-utility analyses of interventions for people with disability where the WHODAS 2.0 has been collected. Mapping algorithms developed from different methods should be considered in sensitivity analyses in economic evaluations.
The Frequency of Intermediate Alleles in Patients with Cerebellar Phenotypes
Authors: Capacci Elena , Bagnoli Silvia , Giacomucci Giulia , Rapillo Costanza Maria , Govoni Alessandra , Bessi Valentina , Polito Cristina , Giotti Irene , Brogi Alice , Pelo Elisabetta , Sorbi Sandro , Nacmias Benedetta , Ferrari Camilla 
Published: October 2023

Abstract Cerebellar syndromes are clinically and etiologically heterogeneous and can be classified as hereditary, neurodegenerative non-hereditary, or acquired. Few data are available on the frequency of each form in the clinical setting. Growing interest is emerging regarding the genetic forms caused by triplet repeat expansions. Alleles with repeat expansion lower than the pathological threshold, termed intermediate alleles (IAs), have been found to be associated with disease manifestation. In order to assess the relevance of IAs as a cause of cerebellar syndromes, we enrolled 66 unrelated Italian ataxic patients and described the distribution of the different etiology of their syndromes and the frequency of IAs. Each patient underwent complete clinical, hematological, and neurophysiological assessments, neuroimaging evaluations, and genetic tests for autosomal dominant cerebellar ataxia (SCA) and fragile X-associated tremor/ataxia syndrome (FXTAS). We identified the following diagnostic categories: 28% sporadic adult-onset ataxia, 18% cerebellar variant of multiple system atrophy, 9% acquired forms, 9% genetic forms with full-range expansion, and 12% cases with intermediate-range expansion. The IAs were six in the FMR1 gene, two in the gene responsible for SCA8, and one in the ATXN2 gene. The clinical phenotype of patients carrying the IAs resembles, in most of the cases, the one associated with full-range expansion. Our study provides an exhaustive description of the causes of cerebellar ataxia, estimating for the first time the frequency of IAs in SCAs- and FXTAS-associated genes. The high percentage of cases with IAs supports further screening among patients with cerebellar syndromes.
Supersonic gas jet stabilization in laser–plasma acceleration
Authors: Lei Zhen-Zhe , Gu Yan-Jun , Jin Zhan , Sato Shingo , Zhidkov Alexei , Rondepierre Alexandre , Huang Kai , Nakanii Nobuhiko , Daito Izuru , Kando Masakai , Hosokai Tomonao 
Published: October 2023

Abstract
Supersonic gas jets generated via a conical nozzle are widely applied in the laser wakefield acceleration of electrons. The stability of the gas jet is critical to the electron injection and the reproducibility of the wakefield acceleration. Here we discussed the role of the stilling chamber in a modified converging–diverging nozzle to dissipate the turbulence and to stabilize the gas jets. By the fluid dynamics simulations and the Mach–Zehnder interferometer measurements, the instability originating from the nonlinear turbulence is studied and the mechanism to suppress the instability is proposed. Both the numerical and experimental results prove that the carefully designed nozzle with a stilling chamber is able to reduce the perturbation by more than 10% compared with a simple-conical nozzle.
Perforating colour lines: Japan and the problem of race in the ‘non-West’
Authors: Untalan Carmina Yu 
Published: October 2023

Abstract
Why do racialised states subscribe to the racial international hierarchy? While the critical scholarship in International Relations (IR) has meaningfully unsettled the discipline’s silence on race, it remains bound to the white versus non-white binary, neglecting the transmission and persistence of racism in international politics outside that divide. This article proposes a Lacanian reading of race as constitutive of state subjectivity in the modern world order to address this gap. Focusing on Lacan’s notion of the ‘lack in the Other’, I suggest that non-West/non-white racism is a fantasy that racialised states construct upon encountering the void of ‘Whiteness’ as a master signifier. I argue that racialised states appropriate racism in response to the anxiety induced by the collapse of the Other’s authority. Using the case of Japan’s transition to a modern nation-state, I mobilise the framework to examine Japan’s flirtation with Western racial theories and subsequent attempts to depart from the white racial order by creating its own racial hierarchy.