bluuebunny/crossref_metadata_2025_split huggingface dataset:
Geomorphologic Changes and Ethnobotany Losses of Indian Sundarbans in Anthropocene
Authors: Mishra Siba Prasad , Chakraborty Triyasha , Barik Kamal Kumar 
Published: November 2023

People in the inter-tidal zones of the Ganga-Brahmaputra-Meghana Delta regions are reliant on mangroves for food, medicine, protection, and livelihood. The present Anthropocene epoch has a deteriorated impact on people's societal, fiscal, and demography due to the climate change loss of agriculture and land use. The mangrove vegetation of Indian Sundarbans is declining in the South 24-Praganna district, West Bengal, the world’s largest estuarine forest, and the UNESCO Heritage, site.
Remote sensing (RS) and geographic information systems (GIS) techniques were used to download data of the Landsat 8 OLI from USGS/GLOVIS of SOUTH 24 Parganas, West Bengal and analysed by ERDAS IMAGINE applications for speculation of the land use/land cover dynamics from the year 2015 to 2020. Ground truthing was conducted by site visits and compiled the medicinal use of plants to investigate the sustenance of SDG-3 and SDG-14.2 and SDG 14.5 of life in the Sundarbans.
The distribution of various mangrove species was identified in the core, buffer and manipulation zones of the Sundarbans Biosphere Reserve, their stratification along the cross-sections, zoning, and use as folk medicines. The research reveals mangrove vegetation is dwindling along the coasts of the South 24 Parganas. There is subsidence, emergence and submergence of land in the archipelago of nearshore Islands. The mangrove loss has been transformed into settlements or agricultural land. Recommendations are made to sustain the inter-tidal vegetation.
Study on Determining the Blood Glucose Concentration During an Intravenous Injection Using Volterra Integral Equations
Authors: Khidir Ahmed A. , Alfaifi Waad I. , Alsharari Salihah L. , Alanazi Ibtisam M. , Alyasi Lujain S. 
Published: November 2023

In this study, the mathematical model for determining the blood glucose concentration during an intravenous injection has been solved throw Volterra integral equation and using Chebyshev spectral method. The method is based on the blending of the Chebyshev pseudo spectral method and its implementation procedure reduces the Volterra integral equation to a system of algebraic equations that are easy to solve. For the practical application of the method, a mathematical model in medical science for determining the blood glucose concentration during an injection has been solved. Tables and figures were generated to verify the accuracy and convergence of the method. The results demonstrate that the method is efficient, convergent and accurate to the exact solution.
An In silico Analysis Study of the Chemical Compounds from the Crassulaceous Plant Bryophyllum pinnatum (Lam.) Oken against the SARS-COV-2 Proteases
Authors: Souza Maycon Douglas Araújo , Souza Hellen Cris Araújo , Viana Edilanne Katrine Amparo , Alves Sabrina Kelly Silva , Sousa Cássio Silva , Ribeiro Arthur Serejo Neves , Vale Vanessa de Sousa do , Rocha Jefferson Almeida 
Published: November 2023

Introduction: Acute severe respiratory syndrome SARS-COV-2, a member of the coronavirus family of enveloped RNA viruses, is the disease-causing agent of COVID-19. Research has been done on the active components of medicinal plants that have therapeutic promise. In this regard, the goal of this work was to investigate the anti-SARS-CoV-2 activity of compounds from the plant Bryophyllum pinnatum (Lam.) Oken.
Materials and Methods: The methodology involved the selection of chemical constituents from the plant leaves in the Pubchem database, in addition to obtaining the protein structures of SARS-CoV-2 (6VXX, 6LU7, 1R42) from the Protein Data Bank (PDB). Docking was carried out using Autodock Tools 1.5.6 and Autodock Vina, with LigPlus for amino acids and Chimera v.13.1 for 3D structures. The most promising compounds were chosen, and the pkCSM tool was used to assess their absorption, distribution, metabolism, excretion and toxicity (ADMET) characteristics.
Results: 264 molecular connections were made from the evaluation of 66 chemical components, 21 of which had binding energies that were less than -8.9 kcal.mol-1. The chemical bryotoxin B produced the highest findings with an interaction energy of -9.9 kcal.mol-1 with the Spike protein, indicating its potential as a SARS-CoV-2 inhibitor. These results are encouraging, but more in vitro and in vivo research is needed to validate the effectiveness of COVID-19 treatments.
Conclusion: The molecular docking study shows promising compounds such as Bryotoxin B, β-amyrin acetate and diosmin in B. pinnatum, with high levels of key proteins of SARS-COV-2. ADMET predictions and these compounds were also developed, indicating the therapeutic potential of B. pinnatum as COVID-19 inhibitors.
MODEL MATEMATIK UNTUK MENENTUKAN NILAI TUKAR MATA UANG RUPIAH TERHADAP DOLLAR AMERIKA
Authors: Halim Siana , Adelia Shirley , Rahardjo Jani 
Published: November 2023

The main objective of this paper is to estimate parameters in the heteroskedasticity models, particularly in Auto Regressive Conditional Heteroskedasticity - ARCH(1) and Generalized Autoregressive Conditional Heteroskedasticity- GARCH(1,1). These models will be used to fit, to forecast and to update the volatility of Rupiah Vs US.Dollar rate.
In order to get the estimation of fitting and updating parameters of ARCH(1) and GARCH(1,1), here will be used iterative method which is derived from the standard maximum likelihood estimation and the initial values are taken from the result of Yule Walker Estimation. The updating parameters will be estimated by using the approach of ARIMA(p,d,q) updating parameters models.
The heteroskedasticity models will give a good fitting even a good forecast in near stasioner condition, however this models can not detect the jump that can be happend due to the changes of political situation that happend in Indonesia.

Abstract in Bahasa Indonesia :

Tujuan utama dari penelitian ini adalah untuk menentukan nilai estimasi pada parameter-parameter yang terdapat pada model-model heteroskedastik, khususnya dalam Auto Regressive Conditional Heteroskedasticity - ARCH(1) dan Generalized Autoregressive Conditional Heteroskedasticity- GARCH(1,1). Model-model ini akan digunakan untuk menentukan, meramalkan dan memperbaharui nilai parameter dari nilai tukar mata uang Rupiah terhadap Dollar Amerika.
Nilai estimasi pada model ARCH(1) dan GARCH(1,1) diperoleh dengan metode iteratif yang diturunkan dari estimasi maksimum likelihood baku dan nilai awalnya didapat dari pendekatan Yule Walker. Penentuan nilai parameter yang diperbaharui akan diestimasi dengan menggunakan pendekatan model ARIMA(p,d,q).
Model-model heteroskedastik memberikan nilai pendekatan nilai tukar yang baik bahkan memberikan nilai peramalan yang baik pula, namun demikian model ini belum dapat mendeteksi terjadinya loncatan yang terjadi yang diakibatkan oleh perubahan situasi politik di Indonesia.

Kata kunci: ARCH, GARCH, YWE, MLE, Heteroskedasticity
Adverse Event Reporting in Randomized Clinical Trials for Multiple Myeloma
Authors: Najjar Mimi , McCarron John , Cliff Edward R. Scheffer , Berger Katherine , Steensma David P. , Al Hadidi Samer , Chakraborty Rajshekhar , Goodman Aaron , Anto Eric , Greene Tom , Sborov Douglas , Mohyuddin Ghulam Rehman 
Published: November 2023

ImportanceCancer treatment can result in burdensome toxic effects that profoundly affect patient quality of life. In seeking to emphasize the efficacy of tested treatments, clinical trial reports may use subjective or minimizing terms to describe adverse events (AEs).ObjectiveTo evaluate patterns of AE reporting in multiple myeloma (MM) randomized clinical trials (RCTs) published between 2015 and early 2023.Design, Setting, and ParticipantsFor this cohort study, the PubMed, Embase, and Cochrane Central Register of Controlled Trials databases were searched to assess the prevalence of minimizing terms in MM RCTs published between January 1, 2015, and March 1, 2023. Minimizing terms were defined as subjective terms used to favorably describe the safety profile of the intervention. The terms searched included convenient, manageable, acceptable, expected, well-tolerated, tolerable, favorable, and safe. Final data analysis was performed on July 21, 2023.Main Outcomes and MeasuresThe primary outcome was the occurrence of at least 1 minimizing term in an article. Univariate logistic regression analyses were performed to evaluate the association between the presence of at least 1 minimizing term and the actual incidence of grade 3 or 4 AEs, serious AEs, or grade 5 AEs.ResultsOf the 65 RCTs included, 56 (86%) used minimizing terms when describing treatment-emergent AEs. The most frequently used minimizing terms were well-tolerated or tolerable in 29 trials (45%), manageable in 18 (28%), and acceptable in 16 (25%). Grade 3 or 4 AE rate in the examined RCTs ranged from 23% to 94%, with a median of 75% (IQR, 59%-82%). A univariate regression analysis demonstrated no association between the use of minimizing terms and grade 3 or 4 AE rates (odds ratio [OR], 1.35 [95% CI, 0.88-2.10] per 10% AE rate increase; P = .17) or grade 5 AE rates (OR, 3.16 [95% CI, 0.27-12.7] per 10% AE rate increase; P = .45).Conclusions and RelevanceThese findings suggest that trial investigators and sponsors regularly use minimizing terms to describe toxic effects in MM trials, and use of this terminology may not reflect actual AE rates in these studies. Instead of using these terms, trial investigators should highlight event rates and patient-reported outcomes, to allow clinicians and patients to better evaluate the true tolerability of AEs.
Unveiling the Double‐Edged Behavior of Controlled Selenium Substitution in Cobalt Sulfide for Balanced Na‐Storage Capacity and Rate Capability
Authors: He Tingting , Zhao Weiming , Hu Junping , Deng Chengjiang , Yan Dong , Huang Shaozhuan 
Published: November 2023

AbstractTransition metal sulfide‐based anodes usually suffer from huge volumetric change and sluggish reaction kinetics, hindering their application for long‐term and high‐power/energy sodium‐ion batteries. Herein, a new design of CoS2‐xSex (0≤x≤2) nanocrystals with highly controllable selenium substitution and S, Se‐codoped graphene immobilization (CoS2‐xSex@SG) is proposed to tune the reaction kinetics and structural stability. The nanocrystal‐on‐graphene structure and robust C─S &C─Se bonding rivets between CoS2‐xSex and SG greatly improve the structural stability of the CoS2‐xSex@SG. Electrochemical performance, kinetic analysis, and theoretical calculation reveal that Se substitution plays a double‐edged role in sodium storage: the increase of Se substitution content enhances the Na+ diffusion kinetics but decreases the Na‐storage capacity. When the Se substitution content is 0.4, the CoS1.6Se0.4@SG electrode demonstrates the best performance: high initial Coulombic efficiency (95.5%), ultrahigh rate capability (412.8 mAh g−1 at 30 A g−1), and ultra‐stable cycling performance (97.6% capacity retention after 1000 cycles). In situ/ex situ measurements further unveil that the conversion reaction between Co0 and Na2S/Na2Se generates the micro‐scaled CoSe2–CoS2 heterostructure, synergistically improving the Na‐storage active sites and reaction kinetics. This work provides a controllable anion substitution strategy to balance the Na+ storage active sites and kinetics with potential applications for high‐power/energy sodium‐ion batteries.
Full‐Color Generation via Phototunable Mono Ink for Fast and Elaborate Printings
Authors: Lee Yun Hyeok , Song Won Jun , Park Jae‐Man , Sung Gimin , Lee Min‐Gyu , Kim Miji , Park Sungeun , Lee Ju Sang , Kim Miyoung , Kim Wook Sung , Sun Jeong‐Yun 
Published: November 2023

AbstractUnlike pigment‐based colors, which are determined by their molecular structure, diverse colors can be expressed by a regular arrangement of nanomaterials. However, existing techniques for constructing such nanostructures have struggled to combine high precision and speed, resulting in a narrow gamut, and prolonged color fabrication time. Here, this work reports a phototunable mono ink that can generate a wide range of colors by controlling regularly arranged nanostructure. Core–shell growth controlled by polymerization time precisely regulates the distance between arranged particles at a nanometer‐scale, enabling the generation of various colors. Moreover, the wide and thin arrangement induces constrained out‐of‐plane growth, thus facilitating the intricate color generation at the desired location via photopolymerization. Upon terminating polymerization by oxygen gas, the generated colors are readily fixed and kept stable. Utilizing programmed ultraviolet illumination, large‐scale and high‐resolution (≈1 µm) full‐color printings are demonstrated at high speed (100 mm2 s−1).
Inkjet Printing of Pharmaceuticals
Authors: Carou‐Senra Paola , Rodríguez‐Pombo Lucía , Awad Atheer , Basit Abdul W. , Alvarez‐Lorenzo Carmen , Goyanes Alvaro 
Published: November 2023

AbstractInkjet printing (IJP) is an additive manufacturing process that selectively deposits ink materials, layer‐by‐layer, to create 3D objects or 2D patterns with precise control over their structure and composition. This technology has emerged as an attractive and versatile approach to address the ever‐evolving demands of personalized medicine in the healthcare industry. Although originally developed for nonhealthcare applications, IJP harnesses the potential of pharma‐inks, which are meticulously formulated inks containing drugs and pharmaceutical excipients. Delving into the formulation and components of pharma‐inks, the key to precise and adaptable material deposition enabled by IJP is unraveled. The review extends its focus to substrate materials, including paper, films, foams, lenses, and 3D‐printed materials, showcasing their diverse advantages, while exploring a wide spectrum of therapeutic applications. Additionally, the potential benefits of hardware and software improvements, along with artificial intelligence integration, are discussed to enhance IJP's precision and efficiency. Embracing these advancements, IJP holds immense potential to reshape traditional medicine manufacturing processes, ushering in an era of medical precision. However, further exploration and optimization are needed to fully utilize IJP's healthcare capabilities. As researchers push the boundaries of IJP, the vision of patient‐specific treatment is on the horizon of becoming a tangible reality.
Nd─Nd Bond in Ih and D5h Cage Isomers of Nd2@C80 Stabilized by Electrophilic CF3 Addition
Authors: Yang Wei , Velkos Georgios , Rosenkranz Marco , Schiemenz Sandra , Liu Fupin , Popov Alexey A. 
Published: November 2023

AbstractSynthesis of molecular compounds with metal–metal bonds between 4f elements is recognized as one of the fascinating milestones in lanthanide metallochemistry. The main focus of such studies is on heavy lanthanides due to the interest in their magnetism, while bonding between light lanthanides remains unexplored. In this work, the Nd─Nd bonding in Nd‐dimetallofullerenes as a case study of metal–metal bonding between early lanthanides is demonstrated. Combined experimental and computational study proves that pristine Nd2@C80 has an open shell structure with a single electron occupying the Nd─Nd bonding orbital. Nd2@C80 is stabilized by a one‐electron reduction and further by the electrophilic CF3 addition to [Nd2@C80]−. Single‐crystal X‐ray diffraction reveals the formation of two Nd2@C80(CF3) isomers with D5h‐C80 and Ih‐C80 carbon cages, both featuring a single‐electron Nd─Nd bond with the length of 3.78–3.79 Å. The mutual influence of the exohedral CF3 group and endohedral metal dimer in determining the molecular structure of the adducts is analyzed. Unlike Tb or Dy analogs, which are strong single‐molecule magnets with high blocking temperature of magnetization, the slow relaxation of magnetization in Nd2@Ih‐C80(CF3) is detectable via out‐of‐phase magnetic susceptibility only below 3 K and in the presence of magnetic field.
Machine Learning in Bioelectrocatalysis
Authors: Huang Jiamin , Gao Yang , Chang Yanhong , Peng Jiajie , Yu Yadong , Wang Bin 
Published: November 2023

AbstractAt present, the global energy crisis and environmental pollution coexist, and the demand for sustainable clean energy has been highly concerned. Bioelectrocatalysis that combines the benefits of biocatalysis and electrocatalysis produces high‐value chemicals, clean biofuel, and biodegradable new materials. It has been applied in biosensors, biofuel cells, and bioelectrosynthesis. However, there are certain flaws in the application process of bioelectrocatalysis, such as low accuracy/efficiency, poor stability, and limited experimental conditions. These issues can possibly be solved using machine learning (ML) in recent reports although the combination of them is still not mature. To summarize the progress of ML in bioelectrocatalysis, this paper first introduces the modeling process of ML, then focuses on the reports of ML in bioelectrocatalysis, and ultimately makes a summary and outlook about current issues and future directions. It is believed that there is plenty of scope for this interdisciplinary research direction.
Nature‐Inspired Electrocatalysts for CO2 Reduction to C2+ Products
Authors: Xu Linlin , Trogadas Panagiotis , Coppens Marc‐Olivier 
Published: November 2023

AbstractThe electrocatalytic reduction reaction of carbon dioxide (CO2RR) has gained significant attention as a promising approach to mitigate carbon dioxide emissions and generate valuable chemicals and fuels. However, the practical application of CO2RR has been hindered by the lack of efficient and selective electrocatalysts, particularly to produce multi‐carbon (C2+) products. Nature serves as an ideal source of inspiration for the development of CO2RR electrocatalysts, as biological organisms can efficiently catalyze the same reaction and possess robust structures that are inherently scaling. In this review, recent advances in the nature‐inspired design of electrocatalysts for CO2RR to C2+ products are summarized and categorized based on their inspiration source, including the coordination sphere of metalloenzymes and the cascade reactions within the enzyme, as well as the local environment. The importance of understanding the fundamental mechanisms and the different contexts between nature and technological application in the design process is highlighted, with the aim to improve the nature‐inspired design of electrocatalysts for CO2RR to C2+ products.
Hydroxy‐ or chlorine‐anchored Pt single‐atom in Al2O3: Which is better for propane dehydrogenation?
Authors: Yang Yanpeng , Liu Qiang , Wang Jingnan , Li Panpan , Miao Chenglin , Liu Jianliang , Yang Yijun , Wang Jieguang , Wang Xi 
Published: November 2023

AbstractPlatinum‐based single‐atom catalysts (Pt1 SACs) can significantly improve the catalytic activity for propane dehydrogenation (PDH) because of their elevated atomic utilization. However, maintaining the high‐temperature stability of the Pt1 species is of utmost importance. To answer the key question: Hydroxy‐ or chlorine‐anchored Pt1 single atoms in Al2O3: Which is the better choice for PDH? We have designed two types of single‐atom Pt catalysts on Al2O3 via a surface group trapping strategy: Pt1–Al2O3 with isolated Pt–O species and Pt1Cl1–Al2O3 with isolated Pt–Cl species. When tested in PDH, Pt1Cl1–Al2O3 showed an exceptional activity of 145 molpropene molPt−1 min−1 at 600°C, which was 3.8 times higher than that of Pt1–Al2O3. It has been demonstrated that the isolated Pt–Cl species in Pt1Cl1–Al2O3 act as an active site and undergoes a dehydrogenation pathway with a lower energy barrier, while Pt1 in Pt1–Al2O3 undergoes a dissociation‐desorption pathway, resulting in few propene productions.
On Cemetery Hill: The legacy of burials at Clemson University, a public university in the southern USA
Authors: Seramur Keith C. , Campbell Kyle B. , Anderson Joseph B. , Cowan Ellen A. 
Published: November 2023

AbstractGround‐penetrating radar (GPR) was used to map anomalies characteristic of unmarked graves on the grounds of the modern Woodland Cemetery on the campus of Clemson University. Hundreds of these anomalies are believed to represent newly discovered unmarked graves belonging to African Americans including enslaved people, convicted laborers, sharecroppers, domestic workers, tenant farmers and wage workers, who contributed to the wealth of the Fort Hill Plantation or to building and maintaining the university. These burials appear to be in an organized arrangement indicating the presence of a burial ground where the graves would have been marked at the time of internment. Analyses of reflections from the bottom of the grave shaft detected horizontal bases as well as possible chambered and vaulted burials, a common vernacular burial type among African Americans in the 19th and early 20th centuries. A fewer number of graves showed hyperbolic reflections that can be produced by graves that contain coffins or a large artefact. This may indicate burial practices that changed over time or the status of the interred individual. The estimated length of the grave shaft in GPR grid data suggests that small adults or adolescents made up most of the burials (58%), then adults (28%) and infants and children (13%). In 1924, Woodland Cemetery was developed on Cemetery Hill, which had its first recorded burial in 1837. Plots were then gifted to prominent University leaders, faculty, staff and their families. The unmarked burials were found juxtaposed among these modern graves requiring modification of the current protocol for the operating cemetery to preserve the sacred space and to prevent destruction of these burials. This work affirms ongoing efforts by this public university to address its origins from a plantation and segregation in the American South.
Kidney Outcomes and Preservation of Kidney Function With Obinutuzumab in Patients With Lupus Nephritis: A Post Hoc Analysis of the NOBILITY Trial
Authors: Rovin Brad H. , Furie Richard A. , Ross Terres Jorge A. , Giang Sophia , Schindler Thomas , Turchetta Armando , Garg Jay P. , Pendergraft William F. , Malvar Ana 
Published: November 2023

ObjectiveTo determine whether adding obinutuzumab to standard‐of‐care lupus nephritis (LN) therapy could improve the likelihood of long‐term preservation of kidney function and do so with less glucocorticoids.MethodsPost hoc analyses of the phase II NOBILITY trial were performed. Time to unfavorable kidney outcome (a composite of treatment failure, doubling of serum creatinine, or death), LN flare, first 30% and 40% declines in estimated glomerular filtration rate (eGFR) from baseline, and chronic eGFR slope during the trial were compared between patients with active LN who were randomized to take obinutuzumab (n = 63) or placebo (n = 62) in combination with mycophenolate mofetil and glucocorticoids. The number of patients who achieved complete renal response (CRR) on 7.5 mg or less per day of prednisone was also determined.ResultsObinutuzumab reduced the risk of developing the composite kidney outcome by 60%, LN flare by 57%, and first eGFR decline of 30% or 40% by 80% and 91%, respectively. Patients receiving obinutuzumab had a significantly slower decline in eGFR than patients receiving placebo, with an annualized eGFR slope advantage of 4.1 ml/min/1.73 m2/year (95% confidence interval 0.14–8.08). Overall, 38% of patients receiving obinutuzumab compared with 16% of patients receiving placebo achieved CRR at week 76 while receiving 7.5 mg or less per day of prednisone (P < 0.01); at week 104, the difference did not achieve significance (38% vs 22%; P = 0.06).ConclusionPost hoc analyses of NOBILITY demonstrated that compared with standard‐of‐care therapy, obinutuzumab treatment resulted in superior preservation of kidney function and prevention of LN flares. More patients achieved CRR at week 76 with less glucocorticoid use in the obinutuzumab group.image