bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH PENDIDIKAN KESEHATAN TERHADAP PENINGKATAN PENGETAHUAN REMAJA TENTANG PENYAKIT HIV/AIDS DI SMKS X JAKARTA
Authors: Nurlindawati  , Kustia Anggereni  , Djimmy Heru Purnomo Babo  , Tri Yunita  
Published: November 2023

Usia remaja merupakan usia produktif yang sangat rentan tertular HIV-AIDS, karena saat remaja mengalami dorongan seksual yang tinggi serta selalu mencari informasi tentang seks, dan pengetahuan dan informasi yang berkaitan dengan kesehatan reproduksi yang didapatkannya sangatlah kurang. Remaja umunya lebih memilih untuk mencari berbagai sumber informasi yang dapat mereka peroleh, seperti, mengakses situs dewasa di internet, percobaan masturbasi, bercumbu atau bahkan bersenggaman dengan pacarnya. Pendidikan kesehatan sangat berperan penting dalam peningkatan pengetahuan dan sikap remaja terhadap pencegahan HIV-AIDS. Tujuan penelitian ini untuk mengetahui pengaruh pendidikan kesehatan terhadap peningkatan pengetahuan remaja tentang HIV/AIDS. Jenis penelitian yang digunakan kualitatif dengan rancangan pra eksperimen dengan one group pretest posttest. Hasil penelitian ini bahwa terdapat pengaruh pendidikan kesehatan terhadap peningkatan pengetahuan remaja tentang HIV/AIDS pada siswa kelas XII SMKS X Jakarta dengan hasil uji chi-square didapatkan p-value = 0,000.
A review of the Ptocasius Simon, 1885 spiders of Gaoligong Mountains, China (Araneae: Salticidae)
Authors: Yang Su-Fang , Peng Xian-Jin 
Published: November 2023

Sixteen new species of the genus Ptocasius are described from Mt. Gaoligong, Yunnan: P. angulatus sp. nov. (♀); P. circulus sp. nov. (♀); P. danzhu sp. nov. (♂♀); P. davidi sp. nov. (♀); P. filiformus sp. nov. (♂♀); P. foliolatus sp. nov. (♀); P. geminus sp. nov. (♂♀); P. jietouensis sp. nov. (♂♀); P. longapophysis sp. nov. (♂♀); P. longlingensis sp. nov. (♂♀); P. rectangulus sp. nov. (♀); P. robustus sp. nov. (♀); P. tengchongensis sp. nov. (♂♀); P. umbellulatus sp. nov. (♀); P. zabkai sp. nov. (♂♀) and P. zonatus sp. nov. (♀). Including P. montanus (Żabka, 1981) and P. pseudoflexus (Liu, Yang & Peng, 2016), a total of eighteen species of Ptocasius have been reported from Mt. Gaoligong. For each new species, a morphological description, photos of the body and copulatory organs, line drawings of copulatory organs, and locality maps are provided.
Posterior vertebrodesis and Ponte osteotomies in surgical treatment of adolescent idiopathic scoliosis type Lenke 1-4
Authors: Ivanov Adelin 
Published: November 2023

The purpose of the study is to present the results of the application of posterior vertebrodesis with Ponte osteotomies (PO) in the operative treatment of adolescent idiopathic scoliosis /AIS/, Lenke 1-4. The study encompasses patients with more than 60 degrees Cobb angle rigid deformities in the frontal plane with correction below 40% percents in the bending tests. Patients with both hyperkyphosis reported in the T5-T12 segment and marked hypokyphosis in the same area of the thoracic zone were also included in the study.
Material and methods
The study encompasses 38 patients (men 11, women 27) with adolescent idiopathic scoliosis type Lenke 1-4 and has been conducted in the period 2010-2018 The patients, included in the study, were of the age between 10 and 18 years, average age: 14.2±0.5.
Results
The following results were reported: Correction at one level osteotomy - 8-11 degrees in kyphosis and less than 5 degrees in the coronal plane; Blood loss at one level osteotomy: 50-95 ml; Time for osteotomy at one level:19-28 min.
Conclusion
Ponte osteotomy and posterior instrumentation with pedicle screws is an effective and relatively safe surgical method to achieve good sagittal and frontal correction in cases with pronounced and rigid thoracic deformities. The performance of osteotomies is associated with increased blood loss and operative time, but it is of key importance in achieving an important correction of the sagittal disorder in hyper or hypokyphosis cases.
Fingertip traumatic amputations in children. Treatment with semiocclusive foil dressings-preliminary results
Authors: Trizlov Dimitar , Raykov Dimitar , Ivanov Stoyan , Trizlov Ivan 
Published: November 2023

Introduction: Traumatic fingertip amputations in childhood constitute 2% of all hand injuries in individuals under the age of 14. These injuries have a significant impact on the psychological and emotional well-being of both the children and their parents. The treatment is multifactorial, dependent on the severity and location of the injury, and can involve both conservative and surgical approaches.
Materials and Methods: The study involved 6 patients between the ages of 8 and 15 with fingertip amputations of the hand. The average duration of treatment with semi-occlusive dressings was between 3-4 weeks. The dressing was changed once a week, and after the final dressing, the border between the wound surface and healthy skin was treated with epithelializing ointments.
Results: The average duration of treatment was 20-30 days. On average, dressings were changed 3-5 times throughout the treatment period. After the completion of treatment, the pulp had a normal shape, and the cosmetic outcome was excellent. No contractures were observed in the adjacent joints, and the two-point discrimination test had an average value of 2.5 mm.
Discussion: Fingertip amputations present challenging injuries with multiple available treatment strategies. The presented technique is relatively simple to apply, reduces pain and discomfort, and allows direct visualization of the wound surface without the need for frequent dressing changes. Treatment with semi-occlusive dressings is a minimally invasive method, particularly suitable for the pediatric age group.
Conclusion: Treatment of fingertip amputations with semi-occlusive foil dressings offers several advantages in childhood. Regular patient follow-up and cooperation from both the child and the parents are essential prerequisites for successful treatment.
Development of bone scaffold from in situ forming hydrogel of Thai silk fibroin and collagen
Authors:   , Apinun Jirun 
Published: November 2023

This study aimed to develop bone scaffold from in situ-forming hydrogel of Thai silk fibroin (SF) and collagen. SF solution was sterilely produced and induced to form gel by oleic acid and poloxamer-188 surfactant combinations with different HLB values. Effect of different HLB values of surfactants on gelation time and physicochemical properties of induced 4 wt% SF with/without 0.1 wt% collagen was studied. Shorter gelation time could be achieved by induction with lower HLB surfactants. SF and SF blended with collagen solution displayed negative charge with added surfactant between HLB1-20. Gel fraction measurement demonstrated inverse relationship between HLB value of surfactants and SF hydrogel stability. There was a trend showing an increase in water absorption capacity of SF with collagen hydrogel induced by surfactants with higher HLB values. Rheological studies revealed an optimum HLB value of surfactants to achieve maximum gel strength. Effect of collagen on modulus of hydrogels was also demonstrated. SEM micrographs showed typical interconnected microporous morphology of all hydrogels. An increase in HLB value of surfactants and addition of collagen resulted in larger pore size with less interporous connectivity and thicker cross-linking networks. DSC study demonstrated more complete crystallization in hydrogels induced by surfactants compared with non-induced hydrogels. There was a trend indicating higher thermal stability of hydrogels with increased HLB value of surfactants. FTIR results demonstrated higher beta-sheet structure in SF hydrogel induced by higher HLB value of surfactants. The presence of collagen precluded this effect. The gelation of SF hydrogels induced by lower HLB surfactant was resulted from interaction between SF and surfactants rather than conformational change to beta-sheet. In vitro cell culture verified the biocompatibility of SF and SF blended with collagen hydrogels with a potential to induce osteogenic differentiation of encapsulated rat’s MSC. However, added collagen promoted proliferation more than differentiation and induced matrix formation. In vivo study in rat demonstrated the biocompatibility and potential of SF/collagen hydrogel as a scaffold and carrier for cell and growth factor for bone regeneration.
Effects of extracting conditions using calcium chloride-ethanol process on characteristics of Thai silk fibroin
Authors:   , Chankow Supawich 
Published: November 2023

Effects of extracting conditions using calcium chloride-ethanol (Ajisawa’s reagent) and lithium bromide (LiBr) process on characteristics of Thai silk fibroin (SF) were studied using 1: 30 - 1: 10 (w/v) dissolving ratios at 50 - 80 °C. Yields of Thai SF extractions were at 63 ± 9 - 74 ± 8 %. The Thai SFs were different in their molecular structures and thermal properties although they were similar in their amino acid compositions, molecular weights, zeta potentials, and viscosities. The Thai SFs extracted with the Ajisawa’s reagent had their random coil contents increased with decreases in the dissolving ratios and increases in the dissolution temperatures. They had their thermal decomposition masses, water evaporation enthalpies, and water contents increased with the random coil contents. Thermal decomposition temperatures of the Ajisawa-derived Thai SFs were slightly higher than those of the LiBr-derived Thai SFs. Relative contents in glycine, alanine, serine, tyrosine, and valine of the Thai SFs were at 46.6 - 48.3 mol %, 29.2 - 32.1 mol %, 4.9 - 8.2 mol %, 4.5 - 5.1 mol % and 2.3 - 2.6 mol %, respectively. Weight average and number average molecular weights of the Thai SFs were at 336 - 340 kilo Daltons and 161 - 167 kilo Daltons, respectively. Heavy-chain was degraded while light-chain was preserved at 25 kilo Daltons by the two dissolution processes. As-casted Thai SF films had their β-sheet contents at 33.8 - 35.0 %. The β-sheet contents of the SF films increased to 38.9 - 40.0 % and 42.8 - 46.7 % after treated with water vapor annealing and ethanol immersion, respectively. All SF films had similar total surface energies. Water vapor annealed SF films exhibited more surface polarities than ethanol treated SF films. The water vapor annealed film fabricated from the LiBr-derived SF was detached after 48 h. Early cell attachments of NIH-3T3 mouse fibroblasts cultured on the water vapor annealed films were higher than those cultured on the ethanol treated films. Both of them had their specific growth rates and population doubling times comparable to the cells cultured on tissue culture plates and glass substrates. The preparation processes affected the molecular structures of the Thai SFs. The SF’s molecular structures further influenced other properties including biocompatibilities with cells.
Apoptosis inducing effect of peptide/protein extracts from lentinus squarrosulus mont. In human h460 lung cancer cells
Authors:   , Prateep Arisara 
Published: November 2023

In searching for the novel compounds with improving efficacy and safety profile for the treatment of lung cancer, anti-cancer activity and underlying mechanism of proteins extracted from Thai edible mushroom, Lentinus squarrosulus Mont. were firstly presented in this study. Proteins from fruiting body of L. squarrosulus Mont. were isolated by precipitation with solid ammonium sulfate at 40-80% (W/V) final concentration and further purified by ion-exchange chromatography on Diethylaminoethyl (DEAE)-cellulose, and gel filtration chromatography on Sephadex G-50 or membrane filtration, respectively. The unbound protein (F1 fraction) and the bound protein eluted with 0.3 M NaCl (F4 fraction) from ion-exchange chromatography showed the highest toxicity to human lung cancer cells with 50% inhibitory concentration (IC50) approximately 22.53 ± 0.22 µg/ml and 21.15 ± 6.14 µg/ml, respectively. The attempt to further purify to homogeneity did not succeed. So proteins from F1 and F4 fractions were used for further studies. The proteins from F4 fraction induced apoptosis cell death through the reduction of anti-apoptosis proteins including Bcl-2 and Mcl-1 which regulated mitochondrial membrane as well as the reduction of c-FLIP, an inhibitor of death receptor pathway. Meanwhile, the induction of apoptosis and the alteration of apoptosis-regulating proteins were not obviously shown in lung cancer cells incubated with proteins from F1 fraction. Although 25 µg/ml of protein from F1 and F4 fraction generated oxidative stress in human lung cancer cells, their anti-cancer activity was reactive oxygen species (ROS) independent. In summary, this study provided the novel information regarding anti-cancer activity and mechanism of proteins from fruiting body of L. squarrosulus Mont. in lung cancer cells which will be beneficial for further development as anti-cancer agent.
Development of paper-based devices for detection of Vibrio parahaemolyticus DNA from loop-mediated isothermal amplification
Authors:   , Tipchote Jutaporn 
Published: November 2023

Vibrio parahaemolyticus (V. parahaemolyticus) is a gram-negative, halophilic marine bacterium and marine seafood-borne pathogen causing gastrointestinal disorders to humans. In this work, colorimetric paper-based device was employed for the determination of V. parahaemolyticus DNA amplified by loop-mediated isothermal amplification (LAMP). LAMP was performed using a set of six specially designed primers which is specific to V. parahaemolyticus DNA. The optimal isothermal amplification was at 65°C for 45 min. After DNA amplifyed by LAMP, colorimetric assay was carried out on paper-based device for DNA determination using silver nanoparticles (AgNPs) as colorimetric agent. It was found that the color of AgNPs did not change in the presence of amplified DNA, whereas color of AgNPs changed from yellow to red in the presence of unamplified DNA. The results of the assay can be easily evaluated by naked eyes. The limit of detection (LOD) was found to be 11.15 CFU mL-1. Therefore, the developed method was used for the determination of V. parahaemolyticus DNA in seafood (shrimps and oysters). Comparison of the results obtained from this proposed method to those obtained by the plate count method (TCBS) and LAMP-gel electrophoresis proved that this developed method has good agreement with the conventional method in terms of accuracy for practical applications. Hence, LAMP-AgNPs on PADs serves as a rapid, inexpensive and simple assay without the need for complicated instrumentation.
Die Verteilungseffekte einer CO2-Bepreisung im Haushaltssektor: Ein systematischer Überblick über die bestehende Literatur
Authors: Bernhofer Dominik 
Published: November 2023

Die Verteilungswirkung einer CO2-Bepreisung und der damit verbundenen Rückerstattung der Einnahmen an die Wirtschaftsakteure ist eine der zentralen Fragen der Ökologisierung unserer Steuersysteme und der Klimapolitik insgesamt. Der vorliegende Artikel versucht auf Basis der bestehenden Literatur, mit speziellem Fokus auf Österreich, die wesentlichen Verteilungseffekte und -kanäle systematisch zu diskutieren. Dabei wird insbesondere zwischen den statischen Verteilungseffekten auf Basis konstanter Einkommen und Warenkörbe und den dynamischen Verteilungseffekten unter Berücksichtigung der Anpassungsreaktionen unterschieden. Die Analyse zeigt, dass die statischen Verteilungseffekte einer CO2-Bepreisung für Österreich klar regressiv sein dürften, der Gesamteffekt aber stark von der gewählten Art der Rückerstattung abhängt. In dynamischer Hinsicht ist ein Rückgang der Steuerbelastung über die Zeit durch Verhaltensanpassungen zu erwarten. Die regressiven Verteilungseffekte könnten sich über die Zeit aber noch verschärfen, weil die Verhaltensanpassungen zB der Heizungstausch nicht für alle Einkommensgruppen gleich erschwinglich sind.

Abstract
The distributional effects of carbon pricing the associated revenue recycling to economic agents is one of the central questions of ecological taxation and climate policy more generally. Based on the existing literature with a special focus on Austria, this article tries to provide a systematic discussion of the central distributional effects and channels. Thereby, the article distinguishes between static distributional effects, given constant household incomes and consumption baskets and dynamic distributional effects, taking behavioural responses into account. The analysis shows that a carbon price for Austria has regressive distributional consequences, whereby the overall effect crucially depends on the form of revenue recycling. From a dynamic perspective, the tax burden should diminish over time due to behavioural responses. The regressive distributional effects however could increase as behavioural responses like changing heating systems are not equally affordable for all income groups.
Angebot an Öffentlicher Kinderbetreuung und Einkommenseinbussen bei Mutterschaft
Authors: Zweimüller Josef , Kleven Henrik , Landais Camille , Posch Johanna , Steinhauer Andreas 
Published: November 2023

Der Artikel diskutiert den Effekt der Ausweitung des Angebots an öffentlicher Kinderbetreuung auf den child penality, die Einkommenseinbussen bei Mutterschaft. Die hier präsentierten Ergebnisse basieren auf der Arbeit von Kleven, Landais, Posch, Steinhaer und Zweimüller (2020), welche den Effekt der Familienpolitik auf diese Einkommenseinbussen untersucht. Diese Studie kommt unter anderem zum Ergebnis, dass der starke Ausbau öffentlicher Betreuungsangebote für Kinder im Vorschulalter (Kindergrippen und Kindergärten) sich nicht in einer Reduktion des child penalty niedergeschlagen hat. Das Ziel der vorliegenden Arbeit ist eine leicht zugängliche Darstellung dieses Ergebnisses sowie der zugrunde liegenden Messkonzepte und Methoden. Am Ende der Arbeit zeihen wir Schlussfolgerungen für die Familienpolitik.
Die Europäische Mindestlohnrichtlinie – Paradigmenwechsel hin zu einem Sozialen Europa
Authors: Müller Torsten , Schulten Thorsten 
Published: November 2023

Die Mindestlohn-Richtlinie gehört zu den wichtigsten arbeits- und sozialpolitischen Maßnahmen, die auf europäischer Ebene verabschiedet wurden. Sie kann zu einem Gamechanger im Kampf gegen Erwerbsarmut und soziale Ungleichheit werden. Sowohl durch Maßnahmen, die auf ein angemessenes (gesetzlichen) Mindestlohnniveaus abzielen, als auch jene die eine Stärkung der Tarifverhandlungen fördern. Der erhebliche Legitimationsverlust des europäischen Integrationsprojekts in der europäischen Bevölkerung hat dabei eine wichtige Rolle gespielt. Die Kommission hat erkannt, dass sie mit dem Krisenmanagement 2008/2009 den neoliberalen Bogen überspannt hat und dass maßgebliche Korrekturen notwendig sind, um der europakritischen Stimmung zu begegnen. Auch die Konstellation im Rat trug dazu bei; einerseits wollte die französische Regierung die Mindestlohn-Richtlinie noch während ihrer Ratspräsidentschaft abschließen, andererseits stellte der Regierungswechsel in Deutschland die Weichen dafür, dass die die Richtlinie sicher ins Ziel gelangte. Die konkrete Bedeutung der Mindestlohn-Richtlinie entscheidet sich letztlich in ihrer Umsetzung auf nationaler Ebene. Sowohl in Ländern mit gesetzlichen als auch in jenen mit tarifvertraglich festgelegten Mindestlöhnen.
Vulvar sarcoma in a young patient with neurofibromatosis syndrome with missed opportunities: A case report
Authors: Kihagi Consolata , Cheserem Eunice , Kamau John , Ndayisaba Dorel , Mokomba Alfred , Kosgei Rose 
Published: November 2023

Background: Vulvar malignancies are the fourth commonest of genital malignancies. The sarcoma type is associated with neurofibromatosis disease.
Case presentation: A 29-year-old nulliparous presented to the outpatient gynecological clinic with a five-year history of a recurrent right vulvar mass. The mass was initially excised without histological analysis. Histological examination of a reexcised mass diagnosed a spindle cell sarcoma. She was then lost to follow-up for one year. The mass recurred and she received external beam radiation. On admission, she was in good general status with generalized café-au-lait spots and neurofibromas. Perineal examination revealed an ulcerated right vulvar mass. Toilet vulvectomy and diversion colostomy were performed followed by chemotherapy. She was discharged after five months with a well-granulated wound. Colostomy was reversed six months later.
Conclusion: Vulvar sarcoma is a rare vulvar malignancy type usually associated with neurofibromatosis. This case highlights the missed opportunities in its management. A high suspicion threshold is critical for early diagnosis and management to curb the morbidity and mortality rate.
Protocolo de autocuidado para pacientes con psoriasis desde la farmacia comunitaria
Authors: Paradas Palomo Teresa , Valverde Merino Maria Isabel , Martinez Martinez Fernando , Zarzuelo Romero Maria Jose 
Published: November 2023

Introducción: Debido a la baja calidad de vida y adherencia al tratamiento de los pacientes con psoriasis se plantea desarrollar un protocolo de empoderamiento que conduzca a un mayor conocimiento del autocuidado en pacientes con esta patología, acorde a sus necesidades, siendo importante el papel del farmacéutico para la mejora de ambos.
Método: Se administró el test Morisky Green-4 items y el cuestionario Dermatology Life Quality Index a 40 pacientes con psoriasis que acudían a una farmacia comunitaria. Con estos datos, la información de las guías clínicas y la colaboración con un dermatólogo, se diseñó un protocolo de autocuidado.
Resultados: Se observó falta de adherencia en el 100% de los pacientes y una calidad de vida leve/moderada (5,3±4,2), en las preguntas relacionadas con: los síntomas cutáneos afectan mucho/muy al 50% de los pacientes y la sensación de vergüenza y dificultad con su tratamiento entre poco y mucho en el 60%. Con estos resultados se diseñaron dos dípticos. A los 3 meses la calidad de vida mejoró a 3,98±2,05, p=0,048, y se observó falta de adherencia en el 70% de los pacientes.
Conclusiones: Los protocolos de autocuidado son necesarios para mejorar la calidad de vida de los pacientes crónicos. El papel del farmacéutico es importante a través de un protocolo de autocuidado en pacientes con psoriasis, ayudando a mejorar la adherencia al tratamiento y la calidad de vida.
Sosialisasi Literasi Keuangan Pada Generasi Muda
Authors: Aslam Annisa Paramaswary , Aswar Nurul Fadilah , Mustafa Muhammad Yushar , Abadi Rahmat Riwayat , Pratiwi Andi Citra 
Published: November 2023

Literasi keuangan mempunyai peran penting dalam mendukung pembangunan keuangan di suatu negara terutama pada negara berkembang seperti Indonesia. Pelaksanaan sosialisasi materi literasi keuangan dilakukan dengan materi seperti pengertian dan tujuan dari literasi keuangan, bagaimana merencanakan keuangan, mengatur pengeluaran dan pendapatan serta contoh instrument investasi keuangan di masyarakat. Kegiatan pengabdian ini dilakukan pada tanggal 28 Mei 2023 dan dilakukan secara daring melalui aplikasi zoom. Pengabdian ini dihadiri oleh 42 peserta yang hadir dalam zoom ini, dimana latar belakang peserta terdiri dari mahasiswa, karyawan swasta, guru, dokter, dan lain-lain yang berasal dari 3 kota di Indonesia yaitu Jakarta, Makassar, dan Surabaya. Tujuan ini pengabdian ini untuk mendukung kebijakan pemerintah mengenai peningkatan literasi inklusi keuangan termasuk meningkatkan pemahaman masyarakat tentang keuangan pribadi, termasuk pengelolaan hutang, perencanaan keuangan, dan investasi.