bluuebunny/crossref_metadata_2025_split huggingface dataset:
A 2-year longitudinal evaluation of the iStent inject® system for open-angle glaucoma in East Asian eyes
Authors: Teoh Ru Jian Jonathan , Yogesvaran Rupini , Cheng Felicia Foo Yuen , Muji Roslinah 
Published: February 2025

Abstract

BACKGROUND:
The aim of the study was to assess the midterm efficacy and safety of the iStent glaucoma device in patients with open-angle glaucoma (OAG).

MATERIALS AND METHODS:
We conducted a retrospective case series of all patients implanted with iStent inject® in OAG. Primary outcomes included intraocular pressure (IOP) and the reduction of antiglaucoma medications. Safety outcomes comprised adverse complications, additional surgeries, and postoperative best-corrected visual acuity (BCVA).

RESULTS:
Eight eyes from eight patients were included in this series. The mean age was 56.3 ± 17.5 years. Six eyes had primary OAG and two eyes had secondary OAG. The majority of eyes (75%) had mild-to-moderate glaucoma. Five eyes underwent combined surgery, whereas the remaining three eyes underwent a standalone procedure. The mean baseline IOP was 22.9 ± 8.2 mmHg, and the mean IOP at 2 years after the procedure was 13.6 ± 2.8 mmHg. There was a 44.5% (10.2 ± 2.5 mmHg; P = 0.002) IOP reduction over 2 years. There was also a reduction in medication burden from a baseline mean of 3.4 ± 0.7 to 2.0 ± 1.2 (P = 0.17). There was no documented intraoperative adverse complication, whereas one patient required trabeculectomy post iStent for IOP control.

CONCLUSION:
iStent inject implantation safely reduced IOP and medication burden up to 24 months postoperative.
Optical coherence tomography findings in patients with diabetic macular edema: A retrospective analysis
Authors: Sivarasu Manjunathan , Madheswaran Gopinath , Balasubramaniam Saranya Sachi , Balasubramaniam Chinnasamy 
Published: February 2025

Abstract

BACKGROUND:
Diabetic macular edema (DME) is a leading cause of vision loss in diabetic people. DME can be treated with various medications, including intravitreal injections, laser therapy, and surgery. Early detection and treatment of DME is essential to prevent vision loss. The study aimed to describe patients’ demographic and clinical characteristics with DME, optical coherence tomography (OCT) findings, and visual acuity outcomes.

METHODOLOGY:
A retrospective study reviewed case records of patients with DME between 2017 and 2020. Demographic data, clinical characteristics, and examination results were extracted and analyzed using Microsoft Excel (2013). All patients clinically diagnosed with DME underwent assessment by OCT examination. DME was classified based on OCT findings. Statistical significance was observed at P < 0.05.

RESULTS:
This retrospective study included 213 eyes of 134 patients, of which 77.6% were male and 22.4% were female. Nonproliferative diabetic retinopathy (NPDR) was present in 51.64% of eyes, and PDR was present in 48.36%. Focal, diffuse, and cystoid macular edema was observed in 68, 31, and 65 eyes, respectively. Tractional macular edema was seen in 16 eyes with posterior hyaloid traction, 13 with epiretinal membrane (ERM), and one with both conditions. DME associated with subretinal fluid (SRF) detachment was seen in 8.92% of eyes. The mean (standard deviation) central retinal thickness was 284.5 (28.9), 434.0 (97.5), 426.5 (27.5), 510.5 (14.1), and 465.5 (280.7) μm in focal, diffuse, cystoid, ERM, and SRF, respectively. Increased central retinal thickness was associated with decreased visual acuity (P < 0.05).

CONCLUSION:
The findings of this study suggest that DME is a common and visually significant complication of diabetes. The OCT findings can be used to classify DME into different subtypes, which may help to guide treatment decisions. Focal edema was the most common type of DME with the least central retinal thickness. In NPDR, focal macular edema was the most common; in PDR, cystoid edema was the most common. Cystoid edema was the most common type in the subgroup of patients with recurrent DME following anti-vascular endothelial growth factor injection.
Spontaneous resolution of photodynamic therapy-induced acute exudative maculopathy in a patient suffering from polypoidal choroidal vasculopathy: A case report with 3-year follow-up
Authors: Rouvas Alexandros , Georgalas Ilias , Tzanidaki Malvina-Efthimia , Gouliopoulos Nikolaos 
Published: February 2025

Abstract
A 60-year-old woman suffering from polypoidal choroidal vasculopathy (PCV) was treated with photodynamic therapy (PDT). The treatment spot was small (850 µm) and was targeted only against the lesion and not the surrounding vascular network. Three days later, she complained of severe visual impairment and the clinical examination set the diagnosis of PDT-induced acute exudative maculopathy (PAEM). Further examinations 3 days later demonstrated on the one hand that subretinal fluid had regressed, but on the other hand, it was identified that PDT possibly resulted in the activation of two other previously quiescent PCV lesions. No other treatment was applied, and the patient’s clinical status was monitored. A new evaluation after 6 weeks, revealed the complete resolution of the exudative phenomena and the significant improvement of vision. Three years later, the condition remains stable. Our report is the first in the literature to describe a case of PAEM following PDT with a small target spot (850 µm), while no other report has demonstrated that PCV-associated PAEM may resolve spontaneously without any treatment. Moreover, the application of PDT was accompanied by the activation of two previously inactive PCV lesions, an adverse effect that has not been previously described.
Isometric dilation and Sarason’s commutant lifting theorem in several variables
Authors: Das B. Krishna , Panja Samir 
Published: February 2025

Abstract
The article deals with isometric dilation and commutant lifting for a class of n-tuples

$(n\ge 3)$

of commuting contractions. We show that operator tuples in the class dilate to tuples of commuting isometries of BCL type. As a consequence of such an explicit dilation, we show that their von Neumann inequality holds on a one-dimensional variety of the closed unit polydisc. On the basis of such a dilation, we prove a commutant lifting theorem of Sarason’s type by establishing that every commutant can be lifted to the dilation space in a commuting and norm-preserving manner. This further leads us to find yet another class of n-tuples

$(n\ge 3)$

of commuting contractions each of which possesses isometric dilation.
On the dynamics of quasi-periodic Schrödinger cocycles for positive measure sets of frequencies
Authors: Bjerklöv Kristian 
Published: February 2025

We consider the family of one-frequency quasi-periodic Schrödinger coycles

G_{\omega,E}

, parametrized by the energy

E

. For potential functions

v(x)=\lambda v_{0}(x)

, where

v_{0}\in C^{2}(\mathbb{T},\R)

is a Morse function with finitely many critical points and

\lambda>0

is large, we show that, for any value of

E\in\R

and for any phase

x^{*}\in\mathbb{T}

such that

|v_{0}(x^{*})-E/\lambda|

is not too small, there exists a set of frequencies

\Omega=\Omega(E,x^{*})

of positive measure such that the following hold: (1) for every

\omega\in\Omega

, the upper Lyapunov exponent of the cocycle

G_{\omega,E}

is

\gtrsim \log\lambda

and

x^{*}

is (essentially) a typical point in Oseledets’ theorem; (2) either

G_{\omega,E}

is uniformly hyperbolic, or there exists a phase

x_{0}\in \mathbb{T}

such that

E

is an eigenvalue of the corresponding discrete Schrödinger operator

H_{x_0,\omega}

.
Transformational Leadership and Teachers' Organizational Commitment: a Systematic Review of 24 Studies in Educational Contexts Aligned With SDG 4
Authors: Xin Chen , Mansor Azlin Norhaini , Amat Salleh Bin , Shihui Hua , Junming Ren 
Published: February 2025

Objective: This Systematic Literature Review explores the impact of transformational leadership on teachers' organizational commitment to education, identifies under-researched themes, and provides recommendations for future research.

Method: The study uses an SLR approach with PRISMA frameworks. Relevant studies were retrieved from Web of Science, Scopus, and ProQuest databases, ensuring comprehensive topic coverage. Literature was systematically screened and selected based on predefined inclusion and exclusion criteria. Data extraction and analysis were performed to synthesize the findings and identify key trends.

Results and Discussion: The relationship between transformational leadership and teachers' organizational commitment in the education context is observed to be significant across various educational stages and regions. The impact of different dimensions of Transformational Leadership on teachers’ Organizational Commitment varies, particularly in normative and Continuity Commitment. Studies in religious countries show cultural influences on this relationship and influence level. While mediators such as job satisfaction and organizational culture play significant roles in this relationship and are explored, moderators remain under-researched, indicating a gap.

Research Implications: Future research should focus on the relationship across educational stages, especially in pre-school and vocational education, to further support the goal of Sustainable Development Goal 4(SDG4). Considering cultural differences, the influence of different dimensions on three levels of teachers’ organizational commitment should be explored, particularly in religious contexts. More research on mediators and moderators needs to be explored. A longitudinal design combining quantitative and qualitative methods is recommended for understanding the long-term effects of the relationship.
The effect of electromyostimulation training on recovery and athlete performance in the sport of volleyball: a review of recent literature
Authors: Iskandar Dedi , Subarjah Herman , Yudiana Yunyun , Ramadan Gilang 
Published: February 2025

Introduction: Electromyostimulation (EMS) training has become a popular method to improve muscle strength and speed up athletes' recovery, especially in the sport of volleyball. However, although many studies support the effectiveness of EMS in individual athletes, its application in volleyball sport, is still not widely researched. Objective: This study aimed to evaluate the effects of EMS on muscle recovery and specific performance in the sport of volleyball. Methodology: The research sought to identify potential benefits and challenges in integrating EMS into volleyball training programmes to maximise overall team performance. The research method involved a comprehensive literature review, with reference to articles published in databases such as PubMed and Scopus. The literature search followed PRISMA guidelines, and only articles relevant to the topic of EMS in volleyball sport were considered. Of the total 220 publications found, only five articles met all inclusion criteria and were further analysed. Results: The results showed that EMS can significantly improve muscle strength and accelerate recovery after intense training, especially in explosive movements such as jumping and change of direction. Discussion: The study also showed that combining EMS with functional training can improve VO2max capacity, muscle strength and physical endurance. However, the application of EMS in the sport of volleyball requires customisation to ensure that it does not disrupt team dynamics and coordination. Conclusions: EMS has the potential to be an effective tool in improving athlete performance and muscle recovery in volleyball sports. However, further research is needed to understand how EMS can be optimally integrated into team training programmes without disrupting team balance. Future research should also evaluate the long-term impact of EMS on team athlete performance.
Carcinoma epidermóide espinocelular de esôfago
Authors: Simões N. L. , Mello F. A. , Moreira R. H. 
Published: February 2025

O câncer de esôfago (CE) é uma neoplasia relativamente incomum e de prognóstico desfavorável, sua etiologia está associada ao tipo histológico da doença, sendo o carcinoma epidermóide, fortemente relacionado ao tabagismo e ao etilismo. O CE em sua fase inicial não apresenta sintomatologia, os sintomas só aparecem em estágios avançados. A presença de disfagia progressiva, odinofagia, desconforto retroesternal, dor epigástrica, náuseas, anorexia e perda significativa de peso, sugerem a existência de carcinoma esofágico. Esse câncer é mais frequente em homens, negros, com mais de 50 anos de idade e de nível socioeconômico baixo. A maioria dos pacientes quando diagnosticados, já não são mais passíveis de um tratamento curativo, necessitando de uma abordagem paliativa. Objetivo: Descrever o caso de um paciente diagnosticado em fase paliativa do CE, atentando a necessidade de uma investigação precoce, já que o CE representa a oitava neoplasia mais comum no mundo. Metodologia: Trata-se de um estudo de caso clínico diagnosticado no hospital Munir Rafful e analisado segundo artigos da base de dados do Medline/Pubmed. Relato: R.G.A., 58 anos, sexo masculino, negro, etilista e tabagista. Dá entrada no Pronto Socorro com queixa de disfagia há 3 meses com evolução progressiva, apresentando no momento resistência a líquidos. Refere perda ponderal de aproximadamente 10kg em 3 meses, associado à inapetência. Ao exame físico: desidratado 2+/4+, desnutrido 3+/4+, hipocorado 2+/4+. Sinais vitais sem alterações. Ausência de lifonodos palpáveis. Aparelho respiratório com murmúrios diminuidos difusamente; aparelho cardiovascular e abdominal sem alterações. Nega febre, hematêmese e melena. Foram solicitados exames laboratoriais, raio-x de tórax, endoscopia digestiva alta (EDA) com biópsia, tomografias de tórax e abdome. Os resultados obtidos foram: exames laboratoriais, raio-x de tórax e tomografia de abdome sem alterações significativas; a tomografia de tórax revelou sinais de enfisema paraseptal em lobos pulmonares superiores e lesão vegetante e infiltrante no terço superior do esôfago; e a EDA evidenciou esôfago com presença de lesão vegetante, infiltrante a cerca de 25 cm dos incisivos supeiores, friável, impedindo a progressão do aparelho, com biópsia confirmatória de carcinoma epidermóide espinocelular. Discussão: Conforme mostra a literatura, o relato de caso apresentado exemplifica a clássica sintomatologia e epidemiologia encontrada no paciente com carcinoma epidermóide de esôfago. Conclusão: Após 16 dias de internação hospitalar, por se tratar de uma neoplasia cirurgicamente irressecável, a equipe optou por realizar uma abordagem paliativa (jejunostomia).
Abordagem Cirúrgica De Emergência No Trauma Hepático
Authors: Marinho J. D. O. , Guidoreni C. G. 
Published: February 2025

A taxa de mortalidade por causas externas no Brasil corresponde a terceira principal causa de morte no país, ficando atrás apenas das doenças cardiovasculares e neoplasias. As principais causas externas são as mortes por acidentes automobilísticos e violência. A faixa etária mais acometida nos acidentes de trânsito são adultos jovens entre 20-29 anos, e as outras causas externas de lesões acidentais, a faixa etária mais acometida são os idosos com mais de 80 anos (DATASUS). A principal forma de combate aos números absurdos de mortes por acidentes é a prevenção. O trabalho é uma revisão de literatura e tem como objetivo elucidar as principais formas de manejo cirúrgico no paciente com trauma abdominal com lesão hepática. As referências apresentadas pela literatura sobre abordagem cirúrgica de emergência no trauma hepático foram coletadas a partir das bases de dados MEDLINE, SciELO, Biblioteca Virtual em Violência e Saúde da Bireme, e livros Trauma- Cirugia, MEDGRUPO, Schwartz’s princípios de Cirurgia. De acordo com os dados do National Trauma Data Bank, principal órgão de registros de trauma nos Estado Unidos, cerca de 40% das vítimas de contusão abdominal apresenta lesão hepática, destes 13% apresentam lesões graves. As lesões penetrantes abdominais acometem frequentemente o fígado e a mortalidade chega a atingir 20%, de acordo com o ATLS. A indicação de laparotomia não depende exclusivamente do grau de lesão hepática, mas sim pelo quadro hemodinâmico, presença de peritonite e necessidade de hemoderivados. Geralmente as lesões graus I, II e III não necessitam de procedimento cirúrgico, porém não são critérios absolutos de indicação ou não de laparotomia. Em traumas abdominais abertos é sempre indicado laparotomia exploradora. As indicações para o tratamento conservador no trauma abdominal contuso com lesão hepática são ausência de peritonite com estabilidade hemodinâmica. Pacientes com lesões graus IV e V com esses critérios necessitam de repouso e acompanhamento de sinais vitais e exames laboratoriais, analisando necessidade de hemoderivados durante a internação, nova tomografia computadorizada (TC) de abdome ou piora do quadro gerando necessidade de laparotomia em segundo momento. Em geral esses pacientes devem ficar os primeiros dois dias em unidade de terapia intensiva (UTI) com monitorização constante. Se a TC mostrar contrast blush deve-se realizar embolização angiográfica. As indicações de laparotomia nos traumas abdominais fechados são instabilidade hemodinâmica ou sinais de peritonite. O reparo cirúrgico pode ser feito através de rafia simples do parênquima, utilização de clipes para hemostasia, tamponamento com compressas, ligadura vascular, hepatectomia e cirurgia para controle do dano (Damage control).
Análise comparativa da ação de sabonetes comuns e com antimicrobianos sob a população de staphylococcus aureus após a higienização simples das mãos
Authors: Ferreira M. D. , Oliveira J. G. , Pereira C. A. S. 
Published: February 2025

Existe um interesse comercial na fabricação de produtos de limpeza que poupem a sociedade dos indesejados germes. Atendendo essa demanda, sabonetes bactericidas foram desenvolvidos para controlar e remover, mecânica e quimicamente, as populações bacterianas da pele. A utilização dessas subtâncias adicionais causam preocupações na comunidade científica pelo seu uso indiscriminado e em longo prazo. Há discussões pertinentes a resistência bacteriana que o componente desses sabonetes, o triclosan, pode causar, assim como a resistência cruzada com outros antimicrobianos. Além disso, a bioquímica desse composto facilita sua absorção pelo organismo, podendo gerar interferência em seu funcionamento. É preciso determinar os custos e benefícios desses produtos, para confirmar se esses elementos agregam ou não eficácia na higienização das mãos. O presente trabalho está em progresso e se objetiva a analisar, comparativamente, o desempenho dos sabonetes comuns e antimicrobianos no momento da pré e póslavagem das mãos do modo preconizado pela Anvisa. Serão coletados swab das mãos de alunos do UniFOA e, em sequência, a cultura dos mesmos em placas contendo ágar Baird Parker e mantidas em estufa bacteriológica a 37oC por até 48 horas. Este procedimento nos fornecerá avaliação quantitativa e qualitativa, por submissão a coloração de Gram, e as cepas que forem cocos gram-positivos serão submetidas ao sistema de identificação bioquímica API STAPH, para confirmar a presença do Staphylococcus aureus.
Análise do Aborto Legal à Luz do Direito, Espiritualidade e seus Reflexos na Relação Médico-Paciente
Authors: Ferreira S. B. , Pacheco C. 
Published: February 2025

A inquietude humana em relação à incessante busca por respostas sobre nossa origem, transfere, para os mais variados cenários em que estamos inseridos, a busca por respostas. Neste viés, a genética proporciona o estudo científico detalhado da questão da gênese humana, onde calorosas – mas saudáveis – discussões, indicam o momento, de acordo com diversas teorias, sobre os pilares iniciais da vida. Entretanto, não obstante a ciência se debruçar sobre o tema, encontra-se indissociável a esta questão os aspectos religiosos, éticos e jurídicos, que não raro, promovem aparentes conflitos ou colisão. Isto se explica devido o ser humano, desde os primórdios, alicerçar aos rumos de sua vida, na espiritualidade e suas liturgias e dogmas – em seu sentido amplo -, pois estes estão umbilicalmente ligados à própria condição humana. E, dentre as várias discussões envolvendo os pilares “vida”, “crença” e “ciência”, campo fértil em que estes aparentes conflitos ocorrem é na relação médico-paciente. Primeiramente devido ao fato do cerne desta relação ser a busca pela vida. Em segundo, pelo fato das pessoas envolvidas (médico e paciente) possuem em sua bagagem interior questões e conflitos éticos, jurídicos, espirituais, dentre outros. Este trabalho tem por escopo identificar as nuances destes aparentes conflitos na seara do aborto, aqui na sua forma legal, pois trata-se de temática polêmica pouco abordada em sua verdadeira amplitude, de tal forma que, não dissecada por completo, amiúde provoca controversas. É público e notório, em nossos dias atuais, que o aborto é uma prática criminosa, tipificada pelo Código Penal Brasileiro. Entretanto, diante da permissão legal para a interrupção de gestação, denominado aborto legal, confabulações a respeito desta permissão suscita questionamentos diante da íntima ligação com os diversos aspectos presentes no âmbito intelectual e social. Assim, em calorosos debates ou conversas corriqueiras, esta temática se apresenta como protagonista de pautas coletivas.
APLIKASI EDUKASI KESEHATAN DAN KEBUGARAN MENGGUNAKAN ALGORITMA NAIVE BAYES
Authors: Reygan Fadhilah Reygan Fadhilah , Faiz Akbar Kamil Muhammad , Hamidin Dini 
Published: February 2025

Semua orang mendambakan untuk melakukan hidup sehat tetapi dengan banyaknya rutinitas tidak bisa melakukan pola hidup sehat. Seperti hal kecil yang mudah dilakukan yaitu minum air putih 8 gelas dalam sehari, tetapi masih banyak orang yang tidak melakukan hal tersebut. Hidup sehat juga memerlukan pola makan teratur, olahraga dan istirahat yang cukup. Selain hidup sehat yang tidak kalah penting yaitu menjaga berat badan agar tetap ideal. Seseorang yang ingin mendapatkan berat badan ideal biasanya akan melakukan diet untuk menurunkan berat badan dengan berbagai program diet yang sudah ada seperti program diet rendah kalori, OCD, program diet kolesterol, dan program diet lainnya.
Pembuatan aplikasi ini yang dilakukan yaitu observasi untuk mengetahui kebutuhan masyarakat sekarang dan teknologi yang berkembang, pengumpulan data untuk proses pembuatan aplikasi, implementasi untuk menerapkan apa saja yang sudah di rancang dan di terapkan pada program dan yang terakhir testing digunakan untuk mencoba aplikasi yang sudah dibuat.