bluuebunny/crossref_metadata_2025_split huggingface dataset:
A correlation and red, amber, green (RAG) analysis of Boditech i-CHROMA™ Prostate Specific Antigen (PSA) Point of Care Test (POCT) Method and Roche PSA laboratory methods
Authors: Bolodeoku John , Gbaa Terry , Anyaeche Chidi , Bass Michael , Makanjuola Jonathan , Kim Tae Kyum , Chinegwundoh Frank 
Published: January 2024

Background: This study evaluated and compared the performance of the Boditech i-CHROMA™ point-of-care testing (POCT) method for the quantification of prostate-specific antigen (PSA) against traditional laboratory PSA method (Roche Methods – Roche Cobas c303/501/502/503, Roche Cobas e402/ e801 and Roche Cobas e411) using external quality control material from RIQAS.
Materials and method: External quality control distributions from RIQAS were analysed using the Boditech i-CHROMA™ PSA method; these were then compared with the results of the Roche Methods – Roche Cobas c303/501/502/503, Roche Cobas e402/ e801 and Roche Cobas e411 provided by participants in the scheme. The mean results of the Roche methods were compared using linear regression and Red Amber Green (RAG) analysis, a scoring system where red is indicative of a raised PSA (>6.0 ng/mL), amber is indicative of a slightly raised PSA (5.0 – 6.0 ng/mL). Green indicates a normal PSA (<5.0 ng/mL).
Results: The data showed that between the Boditech i-CHROMA™ PSA results and the Roche Cobas c303/501/502/503, there was an excellent correlation (r2 = 0.9843). The RAG analysis showed the Boditech i-CHROMA™ PSA method identified 26 reds, two ambers, and six greens compared with 27 reds, two ambers, and six greens determined by the Roche Cobas c303/501/502/503 method. The data showed an excellent correlation between the Boditech i-CHROMA™ PSA results and the Roche Cobas e402/ e801 PSA methods (r2 = 0.9842). The RAG analysis showed the Boditech i-CHROMA™ PSA method identified 30 reds, three ambers, and eight greens compared with 31 reds, two ambers, and eight greens identified by the Roche Cobas e402/ e801 PSA methods. The data showed an excellent correlation between the Boditech i-CHROMA™ PSA results and the Roche Cobas e411 PSA methods (r2 = 0.9851). The RAG analysis showed the Boditech i-CHROMA™ PSA method identified 30 reds, three ambers, and eight greens compared with 31 reds, two ambers, and eight greens identified Roche Cobas e411 PSA methods.
Conclusion: The data showed that the Boditech i-CHROMA™ PSA method is comparable to the Roche Cobas c303/501/502/503, Roche Cobas e402/ e801 and Roche Cobas e411 PSA methods. This could effectively reduce the turnaround time to make prompt decisions on diagnosing, treating, and monitoring of patients with prostate-related disorders.
Penerapan Algoritma K-Means Untuk Mengelompokkan provinsi Di Indonesia Berdasarkan Data Sebaran Covid-19
Authors: Fitriadhi Achmad Furqon Nur , Wahyusari Retno 
Published: January 2024

Pada bulan Desember 2019 di Wuhan, Cina terjadi wabah yang menyerang saluran pernafasan. Awal bulan Januari, WHO menidentifikasi virus tersebut sebagai Coronavirus atau 2019-nCoV yang kemudian mengumumkan nama resmi untuk virus yang melanda adalah COVID-19. Virus COVID-19 tidak hanya terjadi di Wuhan, tetapi juga menyebar ke seluruh dunia. Hal ini tidak terkecuali di Indonesia, sejak Maret hingga April data grafik semakin meningkat signifikan. Tujuan dari penelitian ini adalah menerapkan algoritma K-Means dalam menggelompokkan provinsi berdasarkan tingkat persebaran virus Corona (COVID-19). Penelitian yang dilakukan memiliki keterbaruan dengan menambahkan atribut dalam penentuan kelompok, atribut yang digunakan adalah jumlah positif, jumlah sembuh dan jumlah meninggal. Penelitian menghasilkan 2 (dua) kelompok dengan keanggaotaan klaster 0 menununjukan wilayah yang paling sedikit terdampak covid-19 dengan jumlah 6 data, dan cluster 1 menunjukan wilayah yang paling banyak terdampak covid-19 dengan jumlah 28 data. Dari penelitian ini maka dapat disimpulkan bahwa pemerintah sebaiknya melakukan penanganan covid-19 lebih terfokus pada cluster 1 yang jumlah terdampaknya paling banyak
Perancangan Alat Pengukur Suhu Badan dan Kadar Oksigen Dalam Darah Menggunakan Mikrokontroler
Authors: Wahyusari Retno , Wibowo Lastoni , Amrozi M Ali 
Published: January 2024

Tiga gejala Corona yang paling sering dialami adalah gejala umum seperti demam, batuk, dan sesak napas Berdasarkan hal tersebut, maka pemerintah membuat aturan mengukur suhu tubuh sebelum masuk ruang publik. Meski sebenarnya bukan sesuatu yang menjadi penentu utama, namun tetap kita butuhkan untuk beberapa lokasi publik. Selain suhu tubuh pengecekan kadar oksigen dalam darah juga merupakan salah satu indikasi penting yang diperlukan untuk melihat kesehatan tubuh seseorang. Syarat dinyatakan sehat jika suhu badan dibawah 37o dan kadar oksigen antara 95-100. Alat pengukur suhu badan dan kadar oksigen dalam darah adalah alat yang mendukung penerapan protokol kesehatan. Pemanfaat alat dapat mendeteksi awal adanya gangguan kesehatan berdasarkan suhu badan dan kadar oksigen dalam darah khususnya virus corona. Hasil pengujian menunjukkan bahwa alat yang dibuat memiliki tingkat akurasi diatas 90%, dimana akurasi suhu badan sebesar 94,33% dan akurasi kadar oksigen sebesar 98,63%. Hal ini menunjukkan bahwa alat mampu menggantikan alat pabrikasi, sehingga alat ini layak digunakan untuk membantu terwujudnya era new normal yang memperhatikan protokol kesehatan.
Perancangan Design Game Super Mario Box dengan Pendekatan UI/UX
Authors: Alfaren Geraldo , Gunawan Indra 
Published: January 2024

Perancangan sebuah produk atau aplikasi perlu memiliki desain produk yang efektif dan berjalan secara sistematis. Dalam pembuatan produk yang interaktif, antarmuka (User Interface) diharuskan untuk mudah dipahami dan juga harus dibuat untuk memenuhi pengalaman pengguna atau biasa disebut dengan User Experience. Salah satu produk atau aplikasi yang harus menerapkan UI/UX yang baik adalah game, game Super Mario Box. Tujuan dari penelitian ini adalah membuat desain UI dan UX dalam perancangan game Super Mario Box untuk mendapatkan tingkat kenyamanan dan kesenangan bagi para pengguna. Penelitian menghasilkan aplikasi game yang dirancang menjadi lebih friendly user dan lebih cepat untuk diselesaikan. Salah satunya dengan memberikan fitur-fitur dan kombinasi warna yang simple dan mudah dimengerti.
Active trailing edge flap system fault detection via machine learning
Authors: Gamberini Andrea , Abdallah Imad 
Published: January 2024

Abstract. Active trailing edge flap (AFlap) systems have shown promising results in reducing wind turbine (WT) loads. The design of WTs relying on AFlap load reduction requires implementing systems to detect, monitor, and quantify any potential fault or performance degradation of the flap system to avoid jeopardizing the wind turbine's safety and performance. Currently, flap fault detection or monitoring systems are yet to be developed. This paper presents two approaches based on machine learning to diagnose the health state of an AFlap system. Both approaches rely only on the sensors commonly available on commercial WTs, avoiding the need and the cost of additional measurement systems. The first approach combines manual feature engineering with a random forest classifier. The second approach relies on random convolutional kernels to create the feature vectors. The study shows that the first method is reliable in classifying all the investigated combinations of AFlap health states in the case of asymmetrical flap faults not only when the WT operates in normal power production but also before startup. Instead, the second method can identify some of the AFlap health states for both asymmetrical and symmetrical faults when the WT is in normal power production. These results contribute to developing the systems for detecting and monitoring active flap faults, which are paramount for the safe and reliable integration of active flap technology in future wind turbine design.
El racismo y la islamofobia en el mercado discursivo de la izquierda española
Authors: Gil-Benumeya Flores Daniel 
Published: January 2024

Pese a la asunción de que la izquierda es de por sí antirracista, en los discursos y en la práctica política de la izquierda española la lucha contra el racismo ha solido tener un espacio limitado que solo se amplía de manera coyuntural, y su presencia ha sido aún más marginal en la literatura analítica. La islamofobia, forma de racismo específico contra las personas musulmanas o leídas como tales, no ha recibido hasta ahora una particular atención. El espacio político posterior al 15 M ha heredado estos mimbres. Sin embargo, desde tiempos muy recientes se está verificando un mayor interés por el racismo y el antirracismo en el mercado discursivo de la izquierda, así como un incipiente interés por la islamofobia, debido a una serie de factores que se analizan en este artículo atendiendo a las lógicas internas tanto del campo político como del campo específico del activismo de izquierdas.
Financeirização, meio ambiente e valores
Authors: Ertürk Ismail 
Published: January 2024

A mobilização de recursos financeiros para contribuir com os programas de combate a emergências ambientais é caracterizada por iniciativas voluntárias e gerenciamento de riscos regulatórios. As iniciativas voluntárias tendem a ser orientadas pelo mercado e lideradas pelas Nações Unidas e estão cada vez mais organizadas sob a estrutura Ambiental, Societal e de Governança (ESG – Sigla em inglês). Os bancos centrais, por outro lado, impulsionam uma pressão regulatória para tornar o sistema financeiro estável na transição para uma economia de baixo carbono. Ambas as tendências representam uma abordagem financeirizada dos riscos climáticos e ambientais. Este artigo apresentará uma perspectiva alternativa sobre a financeirização da natureza, repensando criticamente a agenda de riscos climáticos dos bancos centrais e as tecnologias ambientais, sociais e de governança (ESG) aprovadas pelas Nações Unidas que criam um simulacro ambiental nos mercados de capitais. Este documento propõe uma agenda de pesquisa ativista inspirada no trabalho do filósofo Serres sobre a natureza e nas reflexões artísticas sobre o meio ambiente.
Work Life Balance of Women Employees in Banks during Covid-19 Pandemic
Authors: Dr Payal Sharma Upadhyay Ms. Shivani Raina, Mr. Kamal Tamoli, Dr. Neetika, 
Published: January 2024

“Balance is not better time management, but better boundary management. Balance means making choices and enjoying those choices”—Betsy Jacobson.
The growth of a country up to a large extent depends on its economic development and the banking sector is an essential part of it. In the Year 2020 the World Health Organization (WHO) declared the outbreak of COVID-19 as a global health emergency. Bank Employees take strenuous efforts to deliver to the multiple needs of their customers, and during Covid-19 Pandemic, in order to maintain balance between socialising, parenting, running errands and working, the coronavirus has significantly altered the way we live our lives, especially in women bank employees as they have to take strenuous efforts to deliver the multiple needs of/to their customers, in order to strive in the current scenario. Thus we choose the Women working in banking sector as our area of study, for objective of research paper on the work life balance.
In this Research Paper we collect the Primary Data through online questionnaire and telephonic Interviews. The Study will be beneficial to take initiative to establish efficient and effective working environment with satisfaction of Employees in Banking Sector.
Prognostic and immunological roles of heat shock protein A4 in lung adenocarcinoma
Authors: Wu Xuan , Yang Shen-Ying , Zhang Yi-Hua , Fang Jin-Zhou , Wang Shuai , Xu Zhi-Wei , Zhang Xiao-Ju 
Published: January 2024

BACKGROUND
Heat shock protein A4 (HSPA4) belongs to molecular chaperone protein family which plays important roles within variable cellular activities, including cancer initiation and progression. However, the prognostic and immunological significance of HSPA4 in lung adenocarcinoma (LUAD) has not been revealed yet.
AIM
To explore the prognostic and immunological roles of HSPA4 to identify a novel prognostic biomarker and therapeutic target for LUAD.
METHODS
We assessed the prognostic and immunological significance of HSPA4 in LUAD using data from The Cancer Genome Atlas database. The association between HSPA4 expression and clinical-pathological features was assessed through Kruskal-Wallis and Wilcoxon signed-rank test. Univariate/multivariate Cox regression analyses and Kaplan-Meier curves were employed to evaluate prognostic factors, including HSPA4, in LUAD. Gene set enrichment analysis (GSEA) was conducted to identify the key signaling pathways associated with HSPA4. The correlation between HSPA4 expression and cancer immune infiltration was evaluated using single-sample gene set enrichment analysis (ssGSEA).
RESULTS
Overexpressing HSPA4 was significantly related to advanced pathologic TNM stage, advanced pathologic stage, progression disease status of primary therapy outcome and female subgroups with LUAD. In addition, increased HSPA4 expression was found to be related to worse disease-specific survival and overall survival. GSEA analysis indicated a significant correlation between HSPA4 and cell cycle regulation and immune response, particularly through diminishing the function of cytotoxicity cells and CD8 T cells. The ssGSEA algorithm showed a positive correlation between HSPA4 expression and infiltrating levels of Th2 cells, while a negative correlation was observed with cytotoxic cell infiltration levels.
CONCLUSION
Our findings indicate HSPA4 is related to prognosis and immune cell infiltrates and may act as a novel prognostic biomarker and therapeutic target for LUAD.
Development of camel milk cheese technology and research of qualitative characteristics
Authors: Gabrilyants E. A. , Alibekov R. S. 
Published: January 2024

Recently, interest in the production of camel milk and products from it has increased due to its nutritional and medicinal properties, including camel milk cheeses.In this study, the technology of cheese from non-pasteurized camel milk using mesophilic and thermophilic starter cultures was developed. The composition of camel milk and its microbiological safety indicators were studied. Next, three experimental types of camel milk cheese were prepared, where the physico-chemical composition, cheese yield, mineral composition and organoleptic parameters were determined. Thus, the content of the mass fraction of fat in the studied samples ranged from 25.45 to 22.13%. The mass fraction of solids for all samples was in the range of 50.50-62.30%; ash content was 3.05-3.65%; and the mass fraction of proteins was 17.49, 22.19%, respectively, in the control sample, cheese using mesophilic and thermophilic starter cultures. The cheese yield ranged from 115.20g/l to 137.98 g/l. The mineral composition of camel milk cheese showed that macronutrients such as Na, Mg, Ca, K, P. predominate in all samples. Also, all experimental samples of camel milk cheese had high organoleptic characteristics.
БЕЗПЕКА ІНФОРМАЦІЙНИХ СИСТЕМ ВАГОННОГО ГОСПОДАРСТВА
Authors: ДЕМЧЕНКО Юрій Валентинович 
Published: January 2024

Стаття присвячена опрацюванню питань рівню забезпечення інформаційної безпеки вагоноремонтних підприємств, захисту систем зберігання і обробки комп'ютерних даних, при яких зберігається повна конфіденційність, доступність і цілісність всієї наявної інформації. Головною умовою нормальної роботи, повинні бути максимальні знання про всі структурні складові та критерії інформаційної безпеки комп'ютерних даних. Так з кожним наступним роком зростає нагальна роль інформаційної безпеки виробничих процесів, оскільки наше суспільство вступило в нову епоху інформаційних війн, де цінність первинної інформації має неспірній пріоритет. Хоча навіть проста інформація – це не тільки товар, а й значний інструмент для маніпуляції, порушення технологічних процесів, створенню конфліктів, отримання грошової винагороди. Існує нагальна потреба захисту від інформації людини, що тут розглядати ми не будимо, а розглянемо проблему захисту інформації від людини. Отже, інформаційна безпека, це комплекс захищеності всієї інформації та зв’язаної з нею виробничої інфраструктури, від всіх, як випадкових так і навмисних дій, внаслідок чого проходить збій в самій наявній інформації, а також в інфраструктурі підтримки. Мета стороннього проникнення в комп'ютерні мережі підприємства ззовні має ціль нанесення шкоди або знищення якихось наявних даних, заволодіння конфіденційною інформацію з можливим її використанням в противоправних цілях.
Electrical stimulation of acupuncture points in the treatment of arterial hypertension
Authors: Готовский Михаил Юрьевич , Роик Роман Олегович 
Published: January 2024

Цель. Проанализировать и обобщить публикации о применении электрической стимуляции точек акупунктуры при лечении артериальной гипертензии, оценить эффективность, безопасность и характеристики лечебного воздействия. Методы. Обзор публикаций в российских и зарубежных электронных библиотеках за период с 1990 по 2023 год с отбором оригинальных статей и результатов клинических исследований, опубликованных в рецензируемых журналах, по результатам применения электрической стимуляции точек акупунктуры при лечении артериальной гипертензии в рандомизированных условиях с контрольными группами. Результаты. Вошедшие в обзор исследования свидетельствуют о гипотензивном эффекте электрической стимуляции точек акупунктуры Заключение. Электрическая стимуляция точек акупунктуры может быть эффективным и безопасным средством лечения артериальной гипертензии. Дальнейшие запланированные исследования предоставят более подробную информацию.
Aim. To analyze and summarize publications on the use of electrical stimulation of acupuncture points in treatment of arterial hypertension, to evaluate the effectiveness, safety and characteristics of the therapeutic effect. Methods. Review of publications in Russian and foreign electronic libraries for the period from 1990 to 2023 with a selection of original articles and results of clinical studies published in peer-reviewed journals on the results of the use of electrical stimulation of acupuncture points in the treatment of arterial hypertension in randomized conditions with control groups. Results. The studies included in the review indicate the hypotensive effect of electrical stimulation of acupuncture points. Conclusion. Electrical stimulation of acupuncture points may be an effective and safe treatment for hypertension. Future planned studies will provide more detailed information.
Satellite Remote Sensing and Geographic Information System Technologies for Industrial Tree Plantation Mapping and Monitoring: A Way Forward for the Sustainable Development of the Philippine ITP Industry
Authors: Santillan Jojene 
Published: January 2024

KEY POINTS
● Industrial Tree Plantations (ITPs) are a vital contributor to the Philippines' log and timber production, but these ITPs requires better and more efficient way of characterization and monitoring.
● Current policies require ground validations surveys to monitor ITPs for regulation purposes. However, these approaches are often difficult to conduct, time consuming and expensive.
● Satellite remote sensing (SRS) and Geographic Information System (GIS) technologies offer an efficient alternative to traditional ground surveys for mapping and monitoring ITPs.
● SRS and GIS enable detailed mapping of ITPs, including species-level identification, and provides valuable data for forest resource management and environmental monitoring.
● SRS and GIS technologies should be integrated into existing policies by the Department of Environment and Natural Resources (DENR) to efficiently map, monitor, and manage ITPs in the country, ensuring informed decision-making and sustainable forestry practices.
UNRAVELING PAKISTAN-AFGHANISTAN STRATEGIC RELATIONS IN THE POST-US WITHDRAWAL ERA
Authors: Bashir Sonia 
Published: January 2024

The future and prosperity of Pakistan largely relies upon the nature of its relations with neighbouring Afghanistan. The strategic quandaries between Pakistan and Afghanistan like border issues and persistent cross-border terrorism directly affect Pakistan's domestic situation and are producing reverberating influence throughout South Asia. This paper sought to examine the strategic limitations influencing their relations significantly in the wake of American withdrawal from Afghan soil. Furthermore, elucidating the profound impacts stemming from the circumstances after the American exit, it explores the political dimensions and ramifications of their relations. To that end, this research builds multi-dimensional causal relationships and employs qualitative approaches. The study’s findings depict that these strategic constraints are deep-rooted and multifaceted with implications for regional stabilization, manifesting through traditional security conundrums, disruption of trade routes, and obstacles to economic integration. The implications of this study accentuate the pressing need for coordinated measures to promote peace and stability in the region. It concludes by presenting some policy recommendations intended to lessen the existing challenges as well as encouraging a conducive environment to ameliorate relations between Afghanistan and Pakistan.

Bibliography Entry
Bashir, Sonia. 2023. "Unravelling Pakistan-Afghanistan Strategic Relations in the Post-US Withdrawal Era." Margalla Papers 27 (2): 102-114.
ROLE OF MARITIME STRATEGY IN RUSSIAN FOREIGN POLICY: A CASE STUDY OF BLACK SEA
Authors: Sherazi Anees Fatima 
Published: January 2024

Russia is using the Black Sea as a diplomatic tool in its foreign policy to achieve its maritime and foreign policy objectives, which are also linked with the country's strategic culture. This research investigates the significance of the Black Sea in Russia's Maritime Strategy for achieving its foreign policy objectives by using the balance of interest theory. This research employs two conceptual schemas. Firstly, with the help of maritime diplomacy, it analyses a tool to achieve foreign policy objectives in the waters. Secondly, the research uses the concept of strategic culture, which helps explore the diplomatic importance of the Black Sea in Russian foreign policy through the perspective of history and attitudes of decision-makers. This research highlights the case of the Black Sea for Russian maritime strategy, which also has a great economic significance for the region and world. It also highlights the importance of the Black Sea in the Russian maritime doctrine (2022) and links between maritime strategic culture and foreign policy objectives. It concludes that Russia is successfully pursuing its cooperative, coercive, and persuasive maritime diplomacy in the Black Sea region by providing humanitarian assistance, blocking Ukrainian access, and operating a stronghold at Sevastopol port as its naval base. In conclusion, this paper argues that strategic culture plays a vital role in employing the three diplomatic dimensions for achieving maritime objectives in the Black Sea.

Bibliography Entry
Fatima Sherazi, Anees. 2023. "Role of Maritime Strategy in Russian Foreign Policy: A Case Study of Black Sea." Margalla Papers 27 (2): 115-124.