bluuebunny/crossref_metadata_2025_split huggingface dataset:
A qualitative analysis of the impact of government schemes on chronic kidney disease patients in Uddanam, India
Authors: Meka James S. , Choppala Praveen B. , Kombathula Joseph Noel , Kuvala Raj K. 
Published: January 2025

PurposeThis paper presents an analytic report, with precise scientific rigor, the positive impact of the government’s welfare schemes and the areas that need urgent public policy intervention.Design/methodology/approachUddanam, Srikakulam in Andhra Pradesh, a conglomeration of an apportioned group of villages, grapples with a severe and mysterious kidney disease epidemic since the 1980s, affecting agricultural communities. The region, which was once fondly called “Udyanam,” translated as “Garden,” for its richness in greenery and cashew and coconut trees, has now become “Uddanam,” the land of death and despair. The residents of the region suffer with high rates of kidney failure and associated health complications for factors including environmental toxins and poor water quality. Despite several efforts by governments, the impact of governmental policy on improving the conditions has been non-significant. The problem has been taken into sincere and serious consideration by the present Government of Andhra Pradesh which introduced ground-breaking welfare initiatives to impede the prevalence of the disease and the deaths among patients. This paper presents an analytic report, with precise scientific rigor, the positive impact of the government’s welfare schemes, and the areas that need urgent public policy intervention.FindingsThis paper is the first to identify that out of the total of 942 CKD patients interviewed uniformly at random from the Uddanam mandals, a majority of 86.06%, who belong to advanced stages, receive advanced governmental (free) medical care, and soon succumb to the disease, and a minority of 13.94%, who belong to early stages of the disease, do not benefit directly from government welfare schemes, and hence perpetually proceed to advanced stages.Research limitations/implicationsThe qualitative study conducted in this paper is not fully exhaustive; however, the samples are taken uniformly at random from the entire region of influence, which renders the results credible.Practical implicationsThe key findings of this paper will provide a scientific basis for governmental and private health institutions to focus for providing sophisticated medical care for early state CKD patients to further mitigate the mortality rate due to the disease in Uddanam.Social implicationsThis paper shall create a positive social impact of the CKD handling measures taken by governmental and private agencies, and will bring to light the most impending issues that need immediate address, which are of great concern to the international community and media.Originality/valueThis paper is original and the contributions and findings presented herein have not been presented by anyone elsewhere. This paper is also the first to cojoin the impact of medical treatment for CKD at Uddanam and the use of digital technology, e.g. online consultation, online reports, etc.
Introduction to the thematic issue: transformative relationships between tourism and technology
Authors: Liasidou Sotiroula , Pipyros Kosmas 
Published: January 2025

PurposeThe article offers a thorough and insightful examination of the transformative role technology plays in the tourism industry by introducing the articles of the thematic issue.Design/methodology/approachThe discussion approach involves reviewing relevant literature and providing a detailed description of each article in the thematic issue. In particular, the issue consists of a compilation that includes a series of research articles, case studies and theoretical discussions; quantitative and qualitative research enquiries that examine various aspects of tourism technology, such as cybersecurity, digital marketing, smart tourism initiatives, the role of social media and the impact of emerging technologies like artificial intelligence through different perspectives of discussion.FindingsEach article provides useful conclusions that shed light on the various ways that technologies can transform and revolutionize the tourism industry. Technology and tourism have a reciprocal relationship, where technology not only transforms tourism but also shapes it.Originality/valueThis thematic issue contributes and provides new insights into the evolving dynamics of tourism and technology, offering a multidisciplinary perspective that bridges theoretical frameworks and practical applications for industry stakeholders.
The Impact of Postoperative Prophylactic Medication on Long‐Term Surgical, Severe Endoscopic and Endoscopic or Radiologic Recurrence Following Primary Ileocecal Resection in Patients With Crohn's Disease
Authors: ten Bokkel Huinink Sebastiaan , Bak Michiel T. J. , Beelen Evelien M. J. , Erler Nicole S. , Silverberg Mark S. , Allez Matthieu , Hoentjen Frank , Bodelier Alexander G. L. , Dijkstra Gerard , Romberg‐Camps Marielle , de Boer Nanne K. H. , Stassen Laurents P. S. , van der Meulen – de Jong Andrea E. , West Rachel L. , van der Woude C. Janneke , van Ruler Oddeke , de Vries Annemarie C. ,   the Dutch Initiative on Crohn and Colitis (ICC)
Published: January 2025

ABSTRACTBackgroundThe impact of prophylactic medication following ileocecal resection (ICR) for Crohn's disease (CD) merits further elucidation. Prophylactic medication following ileocecal resection (ICR) is recommended in patients with Crohn’s disease (CD), particularly in patients at increased risk of recurrence, but the impact on long‐term outcomes needs to be further elucidated.AimTo evaluate the effect of postoperative prophylactic medication on long‐term prognosis.MethodsA retrospective cohort study was performed in patients with CD who underwent primary ICR between 2000‐2020 in the Netherlands. Patients were divided into two groups: postoperative prophylactic medication [< 12 weeks following ICR] versus no postoperative prophylactic medication. Outcomes were surgical recurrence [re‐resection for CD], severe endoscopic recurrence [modified Rutgeerts score (mRS) ≥ i3] and endoscopic or radiologic recurrence [mRS ≥ i2b or radiologic recurrence]. Inverse probability of treatment weighting [IPTW] method was used to adjust for confounding and selection bias. Survival and association between postoperative prophylactic medication and outcomes were assessed with Kaplan‐Meier analyses and Cox proportional hazard models.Results807 patients underwent ICR (median follow‐up 5.0 years); 36% received postoperative prophylactic medication. Surgical, severe endoscopic and endoscopic or radiologic recurrence rates were significantly lower in those who received prophylactic medication (p = 0.01; p < 0.01; p < 0.01). IPTW analysis showed a lower risk of severe endoscopic and endoscopic or radiologic recurrence in patients treated with postoperative prophylactic medication (aOR 0.64; 95% CI 0.43–0.97; aOR 0.65; 95% CI 0.47–0.91), which also was identified as a protective factor for severe endoscopic (aHR 0.5; 95% CI 0.4–0.6) and endoscopic or radiologic recurrence (aHR 0.6, 95% CI 0.5–0.7) in multivariable analysis after correction for confounding factors. A comparable protective effect of postoperative prophylactic medication was sustained in patients who underwent ileocolonoscopy <1 year postoperatively and who underwent surgery on or after 2010.ConclusionsProphylactic medication following primary ICR significantly reduces long‐term recurrence rates in CD and was identified as a protective factor for severe endoscopic and endoscopic or radiologic recurrence.
Responsive Corporate Social Responsibility: Insights Into Institutional and Agency Factors Influencing Japanese Multinational Enterprises
Authors: Ike Masayoshi , Donovan Jerome Denis , Topple Cheree , Masli Eryadi Kordi 
Published: January 2025

ABSTRACTThis manuscript investigates the factors influencing the selection of responsive corporate social responsibility (CSR) programmes in the subsidiaries of Japanese manufacturing multinational enterprises (MNEs) operating in Indonesia. With a significant and growing manufacturing sector funded by foreign direct investment—of which Japanese MNEs are a major participant—Indonesia offers a novel but significant focus given its low GDP per capita, ecological challenges and being one of the first nations in South‐East Asia to mandate CSR practices. Institutional and agency theories provide a multitheoretical lens for this responsive CSR study enabling a rich, robust framework for addressing both the external and internal drivers of CSR. This study uses a qualitative approach with a sample of four Japanese manufacturing MNEs. The data were collected by interviewing managing directors and CSR personnel of the subsidiary organisations and investigating the CSR practices in secondary data sources from websites and CSR reports from both the headquarter and subsidiary organisations. A proximity effect based on a combination of the size and location of the subsidiary operation was found to be important in determining responsive CSR activities. Personal preferences and connections with the community were also identified as key factors. Feedback loops were identified through MNE CSR reports and websites, which could influence other MNEs and community stakeholders seeking funding. This study's main contribution to the literature is the development of a conceptual framework that details both the internal and external factors influencing the decision‐making process of responsive CSR.
‘Press Start’ on Collaboration: Game‐Based Practices for Fostering Innovative Collaboration in Online Contexts
Authors: Bernal Christopher M. , Lempiälä Tea 
Published: January 2025

ABSTRACTThis study explores the potential of game‐based practices in enhancing organizational innovation, particularly in the context of remote work. Specifically, we examine how collaborative practices within digital gaming environments can inform and enhance the creation of social capital in remote settings and further facilitate collaborative innovation processes. Existing research predominantly focuses on the use of game‐based formats aimed at enhancing idea generation, crowdsourcing, and design processes. However, our research extends this by investigating the sustained application of game‐based practices to foster deeper relationships and cultivate a culture of learning in remote work environments. We present insights from a qualitative study involving 28 interviews with technology professionals equipped with gaming backgrounds. Overall, our results reveal three sets of game‐based practices that hold promise in supporting innovative collaboration in online settings: (1) Rich use of platforms and expressions to achieve interactional sensitivity, (2) Using games as boundary objects to enable idea flows and candid encounters and (3) Routinizing reflective practices and aligning motivations to cultivate learning cultures. Our study highlights the role of game‐based practices in meeting the diverse interactional needs of online collaboration, reducing hierarchical barriers, enabling idea flows and cultivating a learning culture through collective accountability and feedback.
Revealing Molecular Diagnosis With Whole Exome Sequencing in Patients With Inherited Retinal Disorders
Authors: Yavas Cuneyd , Arvas Yunus Emre , Dogan Mustafa , Gezdirici Alper , Aslan Elif Sibel , Karapapak Murat , Barıs Savas , Eroz Recep 
Published: January 2025

ABSTRACTInherited retinal diseases (IRDs) constitute a heterogeneous group of clinically and genetically diverse conditions, standing as a primary cause of visual impairment among individuals aged 15–45, with an estimated incidence of 1:2000. Our study aimed to comprehensively evaluate the genetic variants underlying IRDs in the Turkish population. This study included 50 unrelated Turkish IRD patients and their families. Genomic DNA was extracted from each participant, and candidate variants were identified via next‐generation sequencing to determine their pathogenicity. We detected variants in 58% of the patients, of which six novel variants were identified. Among these, 16 cases exhibited variants associated with retinitis pigmentosa and Stargardt disease, while 13 presented variants linked to other retinal diseases. The spectrum of identified variants included 21 homozygous cases and five compound heterozygous variants, both indicative of autosomal recessive inheritance. Three cases revealed heterozygous variants suggestive of autosomal dominant inheritance, and two cases featured hemizygous variants suggestive of X‐linked inheritance. Importantly, no matches with copy number variants were detected in our analysis. This study comprehensively portrays clinical and genetic profiles within the Turkish population affected by IRDs. Identifying novel variants and delineating inheritance patterns contribute to a deeper understanding of the genetic diagnosis of IRDs, paving the way for more precise diagnostic and therapeutic interventions.
THGS: Lifelike Talking Human Avatar Synthesis From Monocular Video Via 3D Gaussian Splatting
Authors: Chen Chuang , Yu Lingyun , Yang Quanwei , Zheng Aihua , Xie Hongtao 
Published: January 2025

AbstractDespite the remarkable progress in 3D talking head generation, directly generating 3D talking human avatars still suffers from rigid facial expressions, distorted hand textures and out‐of‐sync lip movements. In this paper, we extend speaker‐specific talking head generation task to talking human avatar synthesis and propose a novel pipeline, THGS, that animates lifelike Talking Human avatars using 3D Gaussian Splatting (3DGS). Given speech audio, expression and body poses as input, THGS effectively overcomes the limitations of 3DGS human re‐construction methods in capturing expressive dynamics, such as mouth movements, facial expressions and hand gestures, from a short monocular video. Firstly, we introduce a simple yet effective Learnable Expression Blendshapes (LEB) for facial dynamics re‐construction, where subtle facial dynamics can be generated by linearly combining the static head model and expression blendshapes. Secondly, a Spatial Audio Attention Module (SAAM) is proposed for lip‐synced mouth movement animation, building connections between speech audio and mouth Gaussian movements. Thirdly, we employ a body pose, expression and skinning weights joint optimization strategy to optimize these parameters on the fly, which aligns hand movements and expressions better with video input. Experimental results demonstrate that THGS can achieve high‐fidelity 3D talking human avatar animation at 150+ fps on a web‐based rendering system, improving the requirements of real‐time applications. Our project page is at https://sora158.github.io/THGS.github.io/.
Evaluation of Chatbots in the Emergency Management of Avulsion Injuries
Authors: Mustuloğlu Şeyma , Deniz Büşra Pınar 
Published: January 2025

ABSTRACTBackgroundThis study assessed the accuracy and consistency of responses provided by six Artificial Intelligence (AI) applications, ChatGPT version 3.5 (OpenAI), ChatGPT version 4 (OpenAI), ChatGPT version 4.0 (OpenAI), Perplexity (Perplexity.AI), Gemini (Google), and Copilot (Bing), to questions related to emergency management of avulsed teeth.Materials and MethodsTwo pediatric dentists developed 18 true or false questions regarding dental avulsion and asked public chatbots for 3 days. The responses were recorded and compared with the correct answers. The SPSS program was used to calculate the obtained accuracies and their consistency.ResultsChatGPT 4.0 achieved the highest accuracy rate of 95.6% over the entire time frame, while Perplexity (Perplexity.AI) had the lowest accuracy rate of 67.2%. ChatGPT version 4.0 (OpenAI) was the only AI that achieved perfect agreement with real answers, except at noon on day 1. ChatGPT version 3.5 (OpenAI) was the AI that showed the weakest agreement (6 times).ConclusionsWith the exception of ChatGPT's paid version, 4.0, AI chatbots do not seem ready for use as the main resource in managing avulsed teeth during emergencies. It might prove beneficial to incorporate the International Association of Dental Traumatology (IADT) guidelines in chatbot databases, enhancing their accuracy and consistency.
Jean‐Luc Nancy's Conception of Listening
Authors: Haroutunian‐Gordon Sophie , Laverty Megan Jane 
Published: January 2025

AbstractIn this article Sophie Haroutunian‐Gordon and Megan Jane Laverty discuss Jean‐Luc Nancy's conception of listening as presented in his seminal work, À l'écoute. The authors argue that Nancy uses the term “listening” to refer to the experience of coming to an idea of sound(s) initially encountered as puzzling. They illustrate Nancy's conception with teaching/learning situations involving a pianist and teacher, Deborah Sobol, and two aspiring players, Sophie Haroutunian‐Gordon and Rosalie Romano. The article has four parts. In part 1, the authors ask: Do we see Deborah trying to make meaning of Sophie's performance on October 2, 1998? In part 2, they ask: Do we see Sophie trying to make meaning of Deborah's words and demonstrations on the same occasion? In parts 3 and 4, they explore Sophie's and Rosalie's listening when they are coached by Deborah on January 15, 1999. In so doing, Haroutunian‐Gordon and Laverty illustrate Nancy's conception of listening and demonstrate its usefulness for theorizing about and studying actual situations.
Kindergarten Principals' Ethical Leadership and Teachers' Work Engagement: The Chain‐Mediating Role of Perceived Organizational Support and Voice Behavior
Authors: Yan Zhonglian , Lin Wenqi , Wang Ziqing 
Published: January 2025

ABSTRACTKindergarten principals' ethical leadership, preschool teachers' perceived organizational support, voice behavior, and work engagement are important components that promote high‐quality development in kindergartens. In order to understand the relationship between the four variables, this study conducted an online survey of 819 preschool teachers. The results indicated that (1) ethical leadership was positively correlated with teachers' work engagement; (2) teachers' perceived organizational support and voice behavior play a simple mediating role between ethical leadership and work engagement; and (3) teachers' perceived organizational support and voice behavior also play a chain‐mediating role between ethical leadership and work engagement.
Effect of c‐Myb overexpression on osteoblastic‐, odontoblastic‐, and cementoblastic differentiation of primary human periodontal ligament cells
Authors: Lee Young‐Hee , Yi Ho‐Keun , Pradhan Paras Man , Kim Tae‐Kun , Jang Sungil 
Published: January 2025

AbstractThe periodontal ligament (PDL) is a connective tissue, and PDL cells have a potential to differentiate into cementoblasts, osteoblasts, and gingival fibroblasts. This study investigated whether transcription factor c‐Myb could induce differentiation of PDL cells for periodontal regeneration. PDL cells were isolated from extracted teeth and cultured. c‐Myb was transfected to PDL cells using replication‐deficient adenoviral vector. Differentiation of the PDL cells was analyzed by immunoblot, alkaline phosphatase activity, Alizarin red stain, and immunofluorescence analysis. Cell viability on titanium surfaces was analyzed by crystal violet stain and 3‐(4,5‐dimethylthiazol‐2‐yl)‐2,5‐diphenyltetrazolium bromide (MTT) assay. PDL cells cultured in osteogenic medium showed increased production of osteogenic and cementogenic molecules. Moreover, c‐Myb‐transfected cells showed increased production of dentinogenic molecules, in addition to the osteogenic and cementogenic molecules, even in normal culture condition. c‐Myb‐transfected cells also exhibited increased autophagy and type I collagen production under nutrient deprivation. When grown on a titanium surface, c‐Myb‐transfected cells showed increased production of osteogenesis‐, dentinogenesis‐, and cementogenesis‐related molecules and cell viability. Thus, these results suggest that c‐Myb might play an essential role during periodontal regeneration by improving the differentiation of PDL cells, and c‐Myb can be utilized for enhancing the attachment of PDL cells to dental implant surfaces.
Assessing Site and Species Associations With Beta Diversity of Fish Assemblages in Amazonian Streams
Authors: de Lucena Maria Dayanne Lima , Ribeiro‐Martins André , Casatti Lilian , Vieira Thiago Bernardi , Brejão Gabriel Lourenço , Carvalho Fernando Rogério , Michelan Thaisa Sala , Juen Leandro , de Montag Luciano Fogaça de Assis 
Published: January 2025

ABSTRACT

The increasing environmental changes threatening the fish fauna of streams are driving a growing interest in understanding how sites and species contribute to diversity, as this is important information for decision‐making related to the management and conservation of priority areas and species. The objective of this study was to understand how environmental factors, spatial distance between streams, land use, and land cover (landscape) may be associated with the uniqueness of fish assemblages in Amazonian streams.

We sampled fish assemblages and characterised environmental conditions in 29 streams within and around the Tapajós River basin, near the Amazon National Park in Brazil. Each stream was studied along a 150‐m stretch.

The variables associated with the local contribution to beta diversity (LCBD) were vegetation cover and the presence of refuges. Streams inside and outside the park showed similar contributions to beta diversity. Species richness and abundance showed a negative relationship with LCBD, suggesting that unique sites tended to have few species and low abundance. The species that contributed most to beta diversity (SCBD) had intermediate occurrence, high abundance, and non‐marginal niches. We did not observe an effect of niche breadth on SCBD, as both generalist and specialist species contributed equally to beta diversity.

Our findings underscore the role of environmental variables in ecological uniqueness. Sites unique in species composition may also exhibit low species richness and abundance.

Our study demonstrates the importance of environmental variables in conserving biodiversity in Amazonian streams in the face of environmental changes. By examining the contributions of sites and species, we highlight the importance of considering habitat quality and uniqueness in protecting these ecosystems against the challenges of global change.
Effect of sintering temperature and Y2O3 content on the comprehensive performance of Sialon‒TiB2‒AlN‒cBN composites
Authors: Zhong Shenglin , Wu Yi , Hu Xixi 
Published: January 2025

AbstractThis study focuses on the design of Sialon‒TiB₂‒AlN composite ceramics with thermal expansion coefficients matched to that of cubic boron nitride (cBN), used as binders to synthesize PcBN composites in situ under conditions of ultra‐high pressure (5.5 GPa) and high temperature (1400°C‒1600°C). The effects of sintering temperature and Y₂O₃ content on the phase composition, microstructure, and mechanical properties of PcBN composites were systematically investigated. The results show that the phase compositions of the composites with different sintering temperatures are the same. A moderate addition of Y₂O₃ enhances the formation of Sialon within the system and promotes an increase in its aspect ratio. When the Y₂O₃ content is 2%, both long columnar Sialon and needle‐like (or plate‐like) TiB₂ coexist, with the aspect ratio of Sialon ranging from 4:1 to 5:1. At this composition, the interface bonding is optimal. Under these conditions, the Polycrystalline cubic boron nitride (PcBN) composite exhibits the best overall performance, achieving flexural strength of 990.72 MPa, hardness of 28.49 GPa, fracture toughness of 7.8 MPa·m¹/2, and a maximum wear ratio of 1602.