bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treatment Patterns of Long-Acting Somatostatin Analogs for Neuroendocrine Tumors
Authors: Clarke Callisia N. , Cockrum Paul , Beveridge Thomas J.R. , Jerry Michelle , McMorrow Donna , Tran Anh Thu , Phan Alexandria T. 
Published: December 2023

Background: Long-acting somatostatin analog therapy (LA-SSA) is recommended as first-line therapy for treatment of unresectable or metastatic neuroendocrine tumors (NETs). Understanding treatment sequencing and dosing patterns of LA-SSA is essential for clinical decision-making to provide value-based management of NETs. Objective: To describe treatment patterns of LA-SSA among patients with NETs and subgroups with carcinoid syndrome (CS) in the United States. Methods: This retrospective study utilized claims data from MarketScan® databases to identify patients with NETs and newly treated with LA-SSA between January 1, 2015, and October 31, 2020. Patients were stratified by index LA-SSA (lanreotide and octreotide long-acting release [LAR]). Reported 28-day doses were based on claim fields for days’ supply/drug quantity or units of service. Dose escalation was defined as increases in quantity or frequency. Continuous variables, categorical variables, and Kaplan-Meier estimated treatment durations were compared using t-tests, chi-square/Fisher’s tests, and log-rank tests, respectively. Results: The study included 241 lanreotide and 521 octreotide LAR patients. Compared with octreotide LAR patients, treatment duration was longer for lanreotide patients (median, 41.3 vs 26.8 months; log-rank p=.004). Fewer lanreotide patients received rescue treatment with short-acting octreotide (7.9% vs 14.4%; p=.011), and a first (6.2% vs 27.3%) and second dose escalation (0.8% vs 5.2%; both p<.05). Among patients with doses reported, fewer lanreotide patients received above-label doses (2.5% [5/202] vs 14.4% [60/416]; p<.001). Among patients who ended treatment during follow-up, fewer lanreotide patients transitioned to another LA-SSA (18.9% [17/90] vs 33.6% [92/274]; p=.008). Similar treatment patterns were observed in CS subgroups. Results for switched treatment patterns were limited due to insufficient sample sizes. Discussion: Real-world treatment patterns of LA-SSA were assessed using more recent administrative claims data. Compared with octreotide LAR patients, lanreotide patients were more likely to remain longer on initial treatment and starting dose without dose escalations and less likely to use rescue treatment and transition to another LA-SSA after discontinuation of the index treatment. Conclusions: Findings from this claims study suggest a potential clinical benefit of lanreotide in NET management.
Obstetric Outcomes in Antineutrophil Cytoplasmic Antibody-Associated Vasculitis: An Interview-Based Study in Northern India
Authors: Gupta Latika , Mehta Pankti , Kharbanda Rajat , Balakrishnan Anu , Andreoli Laura , Agarwal Vikas 
Published: December 2023

Introduction:
Rheumatic diseases are associated with poor obstetric outcomes, especially in developing countries. In a multisystem disease like antineutrophil cytoplasmic antibody-associated vasculitis (AAV), pulmonary and renal involvement may contribute to adverse pregnancy outcomes. we explored pregnancy outcomes in women with AAV and compared pregnancies after disease onset to those that occurred before it.

Method:
Women with AAV (Chapel Hill Criteria, 2012) registered at a tertiary care center (2001–2021) were interviewed by teleconsultation or during outpatient visits. Maternal complications and fetal complications were recorded.

Results:
Median age at disease onset was 48 (33–60) years, with the most common subtype being granulomatosis with polyangiitis (13, 48%) followed by microscopic polyangiitis (10, 37%). Twelve women were in the reproductive age group, of which six suffered from a premature menopause. Three pregnancies in three women after disease onset were compared with 62 pregnancies in 23 women with conception before the disease. Pregnancies before disease onset resulted in 58 (93.3%) live birth. One (33.33%) live birth was observed in the pregnancies after disease onset, and disease onset during pregnancy resulting in intrauterine death at 20 weeks period of gestation. One patient is currently in her antenatal period with no complications so far. This study suggests the absence of impact on pregnancy outcome before diagnosis of AAV.

Conclusion:
Pregnancy after a diagnosis of AAV is rare, and successful outcomes may be reported on occasion.
Unified bounds for the independence number of graphs
Authors: Zhou Jiang 
Published: December 2023

AbstractThe Hoffman ratio bound, Lovász theta function, and Schrijver theta function are classical upper bounds for the independence number of graphs, which are useful in graph theory, extremal combinatorics, and information theory. By using generalized inverses and eigenvalues of graph matrices, we give bounds for independence sets and the independence number of graphs. Our bounds unify the Lovász theta function, Schrijver theta function, and Hoffman-type bounds, and we obtain the necessary and sufficient conditions of graphs attaining these bounds. Our work leads to some simple structural and spectral conditions for determining a maximum independent set, the independence number, the Shannon capacity, and the Lovász theta function of a graph.
Comparison of Modified Ferriman-Gallwey Score and Biochemical Parameters in the Estimation of the Prevalence of Idiopathic Hirsutism Among Women in the Kurdistan Region
Authors: Jarallah Bushra , Adil Hataw , Palani Ayad 
Published: December 2023

The word "hirsutism" describes the development of terminal hairs at androgen-controlled body locations in women, which has distress and adverse psychosocial affects. The diagnosis of hirsutism is the key point in the treatment of unwanted hair growth in women’s body. Present study aimed to evaluate the modified Ferriman-Gallwey (mFG) score and the biochemical hyperandrogenism parameters among Iraqi hirsute women and their association with hirsutism in outpatients clinics in Kalar city, Garmian region, Iraq. This was a cross-sectional study of 100 hirsute women were collected from the outpatients clinic and 26 healthy women in Kalar city. After detailed history taking by using structured questionnaire, physical examination, and the relevant investigations were done, the scoring of hirsutism was indexed according to (mFG) scoring system. Moreover, sera of hormonal markers were measured; which included 17-hydroxyprogesterone (17-OHP), total testosterone (TT), free testosterone (FT), dehydroepiandrosterone (DHEA), s. prolactin, and thyroid stimulating hormone (TSH). No statistically significant differences were found in the median of the sex and related hormones between control subjects and the hirsutism group. Likewise, there were no significant relation between hormonal markers and the rate of hirsutism. While, an intrinsic statistical association was seen between the mFG score with the hirsutism and the rate of hirsutism. Our findings imply that the mFG score system is a significance screening tool and has tremendous importance and utility in establishing the diagnosis of hirsutism.
Fundamental Theology
Authors: Becker Matthew L. 
Published: December 2023

Encyclopedic in scope, this book offers wide-ranging coverage of the foundational teachings and practices within the mainstream of the classical Christian tradition. It begins with their roots in the Scriptures, and also branches out into Eastern and Western Christianity, ancient, medieval, and modern, to the present-day.
Part I provides an overview of some of these routes, then presents an historical survey of Christianity’s major traditions. Part II unpacks some of the character of that revelation, focusing particularly on epistemological and procedural questions. Finally, Part III looks at Christian theology in a university setting: the possibility and shape of theology as a university discipline, its major subfields, and its relations with humanities and the sciences respectively.
Fundamental Theology: A Protestant Perspective, 2nd edition, includes a wide range of pedagogical features:
- each chapter begins with an outline thesis statement, highlighted in bold
- charts and graphs
- relevant headings and subheadings employed throughout the book
- keywords
- provides a survey of pertinent reference literature
- questions for review and discussion
- annotated suggestions for further reading
Discourse Analysis and the Greek New Testament
Authors: Porter Stanley E. , O’Donnell Matthew Brook 
Published: December 2023

This volume examines and outlines the Systemic Functional Linguistic (SFL) model of discourse analysis and its relationship to New Testament Greek. The book reflects upon how SFL has grown as a field since it was introduced to New Testament Greek studies by Stanley E. Porter in the 1980s.
The first part introduces basic concepts regarding discourse analysis and the major approaches to discourse analysis within New Testament studies. The second part provides a detailed exploration of discourse analysis in terms of the textual metafunction, beginning with an introduction to the architecture of language within SFL, before exploring several individual elements within it. By focusing upon these individual components – in particular, theme and information structure, markedness and prominence, and coherence and cohesive harmony – Porter and O’Donnell introduce and exemplify the major resources of the textual metafunction.
Hindus and Their Christian Bible
Authors: Sugirtharajah R.S. 
Published: December 2023

R.S. Sugirtharajah shows how at the height of European colonialism whilst the colonizers were studying the sacred texts of Hindus, Muslims, Buddhists, Sikhs and Zoroastrians, the Hindus were themselves scrutinizing the invader’s book – the Christian Bible. Sugirtharajah examines how these Hindus transformed the Bible into what they deemed fit for and suited to their contexts. The result was that the Bible acquired a totally different form and lost its authority as the Book of the Empire. Sugirtharajah shows how the resistant, subversive and at times antagonistic readings of the Hindus went beyond what the colonizer had intended. Sadly what these Hindus made of the Bible went largely unnoticed and was ignored by Western scholarship.
This volume seeks to rectify this regrettable omission and to place both the Hindu reformers and nationalists attitude to the Bible in their own specific context and to allow them to speak on their own terms rather than reading them with Christian preconception. The Hindu reformers covered include figures such as Raja Rammohun Roy, Arumuga Navalar, Keshub Chunder Sen, Swami Vivekananda, Ponnambalam Ramanathan, M. K. Gandhi and Sarvepalli Radhakrishnan and nationalists such as Dhirendranath Chowdhary, Sita Ram Goel and Ram Swarup. The book contains the interpretative context; the textual negotiation that went on between these Hindus and the missionaries and orientalists; examples of their Hinduization of the Bible; and the hermeneutical impact on mainstream biblical interpretation.
The Spirit of Polyphony
Authors: Tarassenko Joanna 
Published: December 2023

This book re-examines how Bonhoeffer employs musical patterns of thought and language to a theological end. It outlines how the significance of Bonhoeffer’s musico-theology has not been sufficiently recognised, and sets the stage for a rigorous re-examination. It becomes clear that through the lens of his musical metaphor of polyphony, Bonhoeffer demonstrates how his account of Christian formation contains a latent pneumatology.
Tarassenko demonstrates that incorporation of this pneumatology is key in deepening one’s understanding of Bonhoeffer. It allows the relationship between Christology and Christian formation in Bonhoeffer’s thought to become fully realised. The appeal to polyphony articulates this pneumatology, as an indirect but nevertheless exceedingly successful means of contouring an account of the Spirit’s work.
A Diplomatic History of US Immigration during the 20th Century
Authors: Montoya Benjamin 
Published: December 2023

This timely book explores immigration into the United States and the effect it has had on national identity, domestic politics and foreign relations from the 1920s to 2006.
Comparing the immigration experiences of Chinese, Japanese, Mexicans, Cubans, Central Americans and Vietnamese, this book highlights how the US viewed each group throughout the American century, the various factors that have shaped US immigration, and the ways in which these debates influenced relations with the wider world. Using a comparative approach, Montoya offers an insight into the themes that have surrounded immigration, its role in forming a national identity and the ways in which changing historical contexts have shaped and re-shaped conversations about immigrants in the United States.
This account helps us better understand the implications and importance of immigration throughout the American century, and informs present-day debates surrounding the issue.
Critical Thinking
Authors: Watson Jamie Carlin , Arp Robert , King Skyler 
Published: December 2023

‘You shouldn’t drink too much. The Earth is round. Milk is good for your bones.’ Are any of these claims true? How can you tell? Can you ever be certain you are right?
For anyone tackling philosophical logic for the first time, here is a practical guide to the skills required to think critically. From the basics of good reasoning to the difference between claims, evidence and arguments, Jamie Carlin Watson, Robert Arp and Skyler King cover the topics found in an introductory course.
Now revised and fully updated, this 3rd edition gives you the chance to develop critical thinking skills that can be used in and out of the classroom. Two new chapters on reasoning in the age of conspiracy theories and fake news demonstrate how to apply reason and avoid being dissuaded by the persuasive power of evidence-free emoting. Features include a glossary, chapter goals, more student-friendly exercises, study questions, diagrams, and suggestions for further reading. Chapter topics, organised around real-life examples such as predicting the weather, a murder mystery and the Ouija board, cover:
- the structure, formation, analysis and recognition of arguments
- deductive validity and soundness
- inductive strength and cogency
- inference to the best explanation
- truth tables
- tools for argument assessment
- informal and formal fallacies
This entertaining and easy-to-follow introduction is a complete beginner’s tool set to good reasoning, analyzing and arguing.
From Action to Ethics
Authors: Sandis Constantine 
Published: December 2023

Over the course of the last decade, Constantine Sandis has advanced our understanding of the role action plays in determining our ethics and motives.
In this collection of his best essays in the philosophy of action, Sandis brings together updated versions of his writings, accompanied by a new introduction. Read collectively they demonstrate the breadth of his interests and ability to relate to broader issues within the culture, connecting debates in philosophical psychology about motivation, negligence, and moral responsibility with Greek tragedy, social psychology, and literature.
Along this path from action to ethics, Sandis engages with Hegel, Wittgenstein, Anscombe, Ricoeur, Davidson, and Dretske, together with contemporary authors such as Jennifer Hornsby and Jonathan Dancy. As he responds to each thinker and theme, he develops his own philosophical position, the key thesis of which is that philosophy of action without ethics is empty, ethics without philosophy of action is blind.
Story Mode
Authors: Case Julialicia , Freeze Eric , Pane Salvatore 
Published: December 2023

Against the backdrop of a hyper-competitive AAA industry and the perception that it is a world reserved for top programmers and hard-core ‘gamers’, Story Mode offers an accessible entry-point for all into writing and designing complex and emotionally affecting narrative video games. The first textbook to combine game design with creative writing techniques, this much-needed resource makes the skills necessary to consume and create digital and multi-modal stories attainable and fun. Appealing to the growing calls for greater inclusivity and access to this important contemporary apparatus of expression, this book offers low-cost, accessible tools and instruction that bridge the knowledge gap for creative writers, showing them how they can merge their skill-set with the fundamentals of game creation and empowering them to produce their own games which push stories beyond the page and the written word.
Broken down into 4 sections to best orientate writers from any technological background to the strategies of game production, this book offers:
- Contextual and introductory chapters exploring the history and variety of various game genres.
- Discussions of how traditional creative writing approaches to character, plot, world-building and dialogue can be utilised in game writing.
- An in-depth overview of game studies concepts such as game construction, interactivity, audience engagement, empathy, real-world change and representation that orientate writers to approach games from the perspective of a designer.
- A whole section on the practical elements of work-shopping, tools, collaborative writing as well as extended exercises guiding readers through long-term, collaborative, game-centred projects using suites and tools like Twine, Audacity, Bitsy, and GameMaker.
Featuring detailed craft lessons, hands-on exercises and case studies, this is the ultimate guide for creative writers wanting to diversify into writing for interactive, digital and contemporary modes of storytelling. Designed not to lay out a roadmap to a successful career in the games industry but to empower writers to experiment in a medium previously regarded as exclusive, this book demystifies the process behind creating video games, orienting readers to a wide range of new possible forms and inspiring them to challenge mainstream notions of what video games can be and become.
Reading Mediated Life Narratives
Authors: Carlson Amy 
Published: December 2023

Calling attention to the unseen mediation and re-mediation of life narratives in online and physical spaces, this ground-breaking exploration uncovers the ever-changing strategies that authors, artists, publishers, curators, archivists and social media corporations adopt to shape, control or resist the auto/biographical in these texts. Concentrating on contemporary life texts found in the material book, museums, on social media and archives that present perceptions of individuality and autonomy, Reading Mediated Life Narratives exposes the traces of personal, cultural, technological, and political mediation that must be considered when developing reading strategies for such life narratives. Amy Carlson asks such questions as what agents act upon these narratives; what do the text, the creator, and the audience gain, and what do they lose; how do constantly evolving technologies shape or stymie the auto/biographical “I”; and finally, how do the mediations affect larger issues of social and collective memory?
An examination of the range of sites at which vulnerability and intervention can occur, Carlson does not condemn but stages an intercession, showing us how it is increasingly necessary to register mediated agents and processes modifying the witnessing or recuperation of original texts that could condition our reception. With careful thought on how we remember, how we create and control our pictures, voices, words, and records, Reading Mediated Life Narratives reveals how we construct and negotiate our social identities and memories, but also what systems control us.
Discovering Indian Philosophy
Authors: Long Jeffery D. 
Published: December 2023

With a history dating back at least 3000 years, the philosophical tradition of India is one of the oldest to continue to thrive today. Encompassing a wide variety of worldviews, Indian philosophy includes perspectives that have ongoing relevance to contemporary issues such as the nature of consciousness, the relationship between philosophy and the good life, the existence of a divine reality, and the meaning of happiness. Contrary to widespread stereotypes, Indian philosophy is not simply an extension of Indian religion. Scepticism is a pervasive feature of this discourse, and there is even a school of thought which affirms materialism. The idea of a divine reality is debated extensively, not only in terms of the existence of such a reality–“Is there a God?”–but also in terms of its nature–“What is God?”
This book, drawing upon some of the latest research in the field, traces the history of the Indian philosophical tradition from ancient times to the present, outlining the views and major thinkers of such schools of thought as Vedanta, Jainism, Buddhism, and many more. Jeffery D. Long treats each system, however, not simply as an historical artifact, but as a living reality with important insights to offer our world today. It is essential reading for anyone interested in world philosophies and how they address the ‘big questions’ that have always engaged human beings
The Holocaust Sites of Europe
Authors: Winstone Martin 
Published: December 2023

The Holocaust is the gravest crime in recorded history. In order to try and better understand the true significance of the Holocaust, as well as its scale and magnitude, millions of people each year now travel to the former camps, ghettos and other settings for the atrocities. The Holocaust Sites of Europe offers the first comprehensive guide to these sites, including much practical information as well as the historical context.
This book is an indispensable guide for anyone seeking to add another layer to their understanding of the Holocaust by visiting these important sites for themselves. It provide a survey of all the major Holocaust sites in Europe, from Belgium and Belarus to Serbia and Ukraine: not only does it discuss the notorious concentration and death camps, such as Auschwitz and Ravensbruck, but also less well known examples, like Sered' in Slovakia, together with detailed descriptions of massacre sites, as well as the ghettos, 'Euthanasia' centres and Roma and Sinti sites which witnessed similar crimes. Throughout the book there is also extensive insight into the many museums and memorials which commemorate the Holocaust.
The Holocaust Sites of Europe is a thoughtful and fitting guide to some of the most traumatic sites in Europe and will be an invaluable companion for those who wish to honour the victims and understand more about their fate.
Reading Audio Readers
Authors: Berglund Karl 
Published: December 2023

The first computational study of reading to focus on audiobooks, this book uses a unique and substantial set of reader consumption data to show how audiobooks and digital streaming platforms affect our literary culture. Offering an academic perspective on the kind of user data hoard we associate with tech companies, it asks: when it comes to audiobooks, what do people really read, and how and when do they read it?
Tracking hundreds of thousands of readers on the level per user and hour, Reading Audio Readers combines computational methods from cultural analytics with theoretical perspectives from book history, publishing studies, and media studies. In doing so, it provides new insights into reading practices in digital platforms, the effects of the audiobook boom, and the business-models for book publishing and distribution in the age of streamed audio.