bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Honey/PVA Hydrogel Loaded by Erythromycin on Full-Thickness Skin Wound Healing in Rats; Stereological Study
Authors: Movassaghi Shabnam , Sharifi Zahra Nadia , Koosha Mojtaba , Abdollahifar Mohammad Amin , Fathollahipour Shahrzad , Tavakoli Javad , Abdi Shabnam 
Published: December 2023

Background: Skin wounds are a significant public health risk, and treatment of wound remains a challenging clinical problem for medical teams and researchers.Materials and Methods: In the present study, we aimed to investigate the healing effects of honey/polyvinyl alcohol (PVA) hydrogel loaded with erythromycin Â as wound dressing on skin wounds in rats, based on histological studies. In this study, 60 male Wistar rats, with a 1.5 Ã—1.5 cm2 diameter full-thickness wounds on the backs were divided into four groups: honey/PVA with the erythromycin hydrogel group, honey group, PVA group, and the control group, with no treatment. Skin biopsies were prepared at days 4, 7, and 14 for microscopic analyses. The stereological analysis, including the mean area of the wound, length of vessels, numerical density of fibroblast, macrophage, basal cell and volume of the epidermis, dermis, and fibrous tissue were performed.Â Result: Wounds area in the honey/PVA hydrogel with the erythromycin group were significantly (P<0.05) smaller than in the other group. The numerical density of fibroblast, macrophage, basal cell and volume of the epidermis in the honey/PVA hydrogel with the erythromycin group were significantly higher than other groups.Conclusion: According to our results, honey/PVA hydrogel with erythromycin may promote early wound healing and has a positive influence on fibroblast proliferation and re-epithelialization, and its administration is recommended after further validation of clinical data.
[GMJ. 2019;8:e1362]
Neuroprotective Effect of Pentoxifylline on 3,4-Methylenedioxymethamphetamine-Induced Apoptosis in CA1 Cells of Wistar Rat Hippocampus
Authors: Sharifi Zahra Nadia , Movassaghi Shabnam , Khazaei Koohpar Zeinab , Hashemi Mehrdad , Jafari Semnani Sourena 
Published: December 2023

Background:Â 3,4-Methylenedioxymethamphetamine is psychoactive and hallucinogenic and has been shown to produce neurotoxicity both in animals and in humans. Recently, vasodilator drugs such as pentoxifylline (PTX) have been introduced as an alternative with neuroprotective effects. There is no study about the protective effect of PTX on hippocampal apoptosis due to high-dose administration of 3,4-Methylenedioxymethamphetamine (MDMA), so in this study, the protective effect of PTX on the hippocampus of male Wistar rats following high-dose of the drug has been investigated. Materials and Methods: Twenty-four male Wistar rats weighing 250-300 g were randomly divided into four groups: control, sham (MDMA injection), experimental (MDMA+PTX injection), and vehicle (MDMA+saline) groups. Two weeks later, the brains were removed and prepared for TUNEL and western blot techniques. Concomitantly the hippocampus was removed to study the change in Bcl-2 and BAX mRNA expression with quantitative real-time polymerase chain reaction. Results: Data showed that the number of apoptotic bodies significantly decreased in the experimental group compared to the other groups, except for in control. Also, further investigation revealed that BAX reduced considerably, while Bcl-2 mRNA expression increased dramatically after PTX treatment. Conclusions: Our results suggest that PTX may be a neuroprotective agent, and its neuroprotective potential may contribute to reducing the severity of lesions in the hippocampus following a high dose administration of MDMA. [GMJ.2019;8:e963]Â
The Relationship between Left Ventricular Function Indices in Tissue Doppler Imaging and Exaggerated Blood Pressure Response During the Exercise Stress Test
Authors: Ghaderi Fereshteh , Hemati Milad , Gholoobi Arash , Eshraghi Ali , Sadeghi Allah Abadi Javad 
Published: December 2023

Background: Studies have indicated that exaggerated hypertension during activity and stress can be a good predictor of the incidence of hypertension. This study tries to evaluate left ventricular (LV) function by tissue Doppler to assess early changes in ventricular compliance before the onset of Hypertension (HTN) in patients with exaggerated blood pressure response during the exercise test. Materials and Methods: In this case-control study, 40 patients without a history of hypertension with systolic blood pressure less than 140/90 which referred for exercise test, were included. The exercise test was performed for all patients. Patients who had exaggerated blood pressure during the stress test were considered as cases and the controls with normal blood pressure responses. Then standard echocardiography and Tissue Doppler imaging performed and indices of LV systolic and diastolic were recorded. Results: The LV mass in cases and controls were 174.9Â±50.78 and 152.9Â±33.59, respectively (P=0.114), and LV mass index in cases and controls were 127.4Â±13.5 and 79.8Â±15.75, respectively (P=0.023). Moreover, the LV Myocardial Performance Index were 0.68Â±0.11 and 0.48Â±0.06 in cases and controls, respectively (P<0.001). The heart rate, E/A, EE, E Velocity and S velocity were measuremented. Except E/A (P=0.009), there was no significant difference between the other variables measured between the cases and controls (P>0.05). Conclusion: The results of this study showed that using 2D conventional echocardiography as a noninvasive method if performed in prestigious centers can evaluate systolic and diastolic function Tissue Doppler parameters very well in the early stages of heart disease caused by HTN. [GMJ.2020;9:e1323]
Introducing Serine as Cardiovascular Disease Biomarker Candidate via Pathway Analysis
Authors: Zamanian Azodi Mona , Rezaei Tavirani Mostafa , Rostami-Nejad Mohammad , Morravej Hamideh , Razzaghi Zahra , Okhovatian Farshad , Rezaei-Tavirani Majid 
Published: December 2023

Background: The rate of death due to cardiovascular disease (CVD) is growing. Investigations about CVD that leading to introduce varieties of metabolites is available. The monitoring of these metabolites to find effective ones in the future of clinic applications is the main aim of this study. Materials and Methods: Numbers of 34 metabolites for the CVD are extracted from literature and designated for interaction determinations by MetScape V 3.1.3. The compound-reaction-enzyme-gene network was constructed and the pathways were analyzed. Based on the presence of metabolites in the pathways the critical compounds were determined. Results: Pathway analysis revealed 18 disturbed pathways related to the CVD. glycerophospholipid metabolism pathway including 27 compounds is related to the 9 queried metabolites. L-Serine which was communed between 5 pathways and also was presented in the largest pathway was identified as the critical compound. Conclusion: It can be concluded that L-Serine is a proper biomarker candidate for CVD diagnosis and also patients follow up approaches. [GMJ.2020;9:e1696]
Sexual Health Literacy, a Strategy for the Challenges of Sexual Life of Infertile Women: A Qualitative Study
Authors: Rakhshaee Zahra , Maasoumi Raziyeh , Nedjat Saharnaz , Khakbazan Zohreh 
Published: December 2023

Background: Sexual health literacy enables an understanding and application of sexual health information and has benefits beyond health. Health literacy is an important element for achieving cognitive skills in health promotion. One of the most important problems in sexual health and sexual function in women is infertility. This study aims to explore the dimensions of sexual health literacy among women with infertility. Materials and Methods: In this qualitative study, a total of 18 individual interviews with 15 Iranian women with infertility, and three key informants, were conducted in infertility centers in Rasht (the North of Iran). Data were collected through in-depth semi-structured interviews using interview guide questions. Data were analyzed using the conventional content analysis approach. Results: Five themes emerged: informational needs of sexual health, information seeking, informational perception, validation of information, and information application. Sexual issues are taboo in Iranian culture. They are not taught in health and educational centers. All the participants believed that there was a lack of information about the sexual response cycle, preventing sexually transmitted infections, targeted intercourse, and consequences of infertility in sexual life. Participants mentioned the embarrassment, privacy, and lack of centers for sexual health as information-seeking barriers. Searching different sources and questioning the informants were ways for understanding information. Women evaluated the accuracy of the information by considering the validity of the source of information, comparing information from different sources, and asking the experts. They applied the information received about sexual health, satisfaction, and especially targeted intercourse to increase the chance of pregnancy. Conclusion: Sexual health literacy in infertile women includes different dimensions. It can help promote sexual health, satisfaction, and increasing the chance of pregnancy. [GMJ.2020;9:e1862]
Infiltration of Mast Cells in Scalp Biopsies of Patients with Alopecia Areata or Androgenic Alopecia Versus Healthy Individuals: A Case-Control Study
Authors: Nasiri Soheila , Salehi Alireza , Rakhshan Azadeh 
Published: December 2023

Background: Alopecia areata (AA) and androgenic alopecia (AGA) are the most common types of alopecias. Recently, the role of mast cells in inflammatory diseases has become the focus of many studies. However, few studies have been conducted on their role in AA and AGA. Therefore, our study aimed to quantitatively evaluate the presence of mast cells in the AA and AGA specimens.Materials and Methods: Three groups of AA, AGA, and healthy control were studied (each group with 20 subjects). Patients were randomly selected from those referred to the dermatology clinics of Shahid Beheshti University. Specimens were obtained from the scalp, and perifollicular and perivascular areas were investigated. Results: Significantly higher perifollicular and perivascular mast cell counts were seen in both AGA and AA groups compared to healthy control (P<0.001 for both). Moreover, AA patients had more frequent perivascular mast cells than the AGA group (P=0.042). Among patients aged <40 years, perifollicular and perivascular mast cell counts were not significantly different among the three groups; however, subjects over 40 years of age in both groups had significantly more perifollicular and perivascular mast cells than healthy participants. There was a significant positive correlation between disease severity and mast cell counts in both perifollicular and perivascular areas in AA patients (P=0.001 for both). Conclusion: There was a significantly increased infiltration of mast cells in AA and AGA patients, and this increase was age and severity dependent. Moreover, the increase in mast cell proliferation is more dominant in AA patients. [GMJ.2020;9:e1962]
Prevalence of Intimate Partner Violence in Pregnancy in a Province of Türkiye, Changes in Violence and Effects on Maternal Mental Health
Authors: DURMAZ Elif , NAZLICAN Ersin 
Published: December 2023

Objective: The aim of this study was to evaluate the frequency of intimate partner violence (IPV) during pregnancy and the effect of violence on maternal mental health.
Materials and Methods: The hospitals in Adana province center was selected by simple randomization method. Frequency tables, chi-square test and multiple logistic regression analysis were used as statistical analysis.
Results: Prevalence of IPV was found as 24.1% before pregnancy and 17.5% during pregnancy. The rate of emotional, physical and sexual IPV exposure during pregnancy was found as 16,7%, 2,8% and 3,3%, respectively. It was found that regarding 69% of those exposed to violence in any period of their life, the rate of overall violence either decreased or completely ceased during pregnancy. Women, who experienced IPV during pregnancy were 4.60 times more likely to have depression in pregnancy.
Conclusion: It has been determined that the rate of IPV exposure decreases with pregnancy however, IPV during pregnancy causes mental health problems in women.
Research on Semantic Segmentation of Fish-Eye Images for Autonomous Driving
Authors: Huang Hongtao , Tian Xiaofeng , Tian Wei 
Published: December 2023

Abstract: Fisheye cameras, valued for their wide field of view, play a crucial role in perceiving the surrounding environment of vehicles. However, there is a lack of specific research addressing the processing of significant distortion features in segmenting fish-eye images. Additionally, fish-eye images for autonomous driving face the challenge of few datasets, potentially causing over fitting and hindering the model's generalization ability.
Based on the semantic segmentation task, a method for transforming normal images into fish-eye images is proposed, which expands the fish-eye image dataset. By employing the Transformer network and the Across Feature Map Attention, the segmentation performance is further improved, achieving a 55.6% mIOU on Woodscape. Additionally, leveraging the concept of knowledge distillation, the network ensures a strong generalization based on dual-domain learning without compromising performance on Woodscape (54% mIOU).
ANTI-APOSTATIC FEEDING BEHAVIOR IN TWO SPECIES OF ASSASSIN BUG, THE WHITE-SPOTTED ASSASSIN BUG PLATYMERIS BIGUTTATUS AND RED-SPOTTED ASSASSIN BUG PLATYMERIS RHADAMANTHUS (HEMIPTERA: REDUVIIDAE)
Authors: Potocnjak Julia H. , Vitek Christopher J. 
Published: December 2023

Abstract
Predator-prey relationships are a driving force when examining community ecology. One question in predator-prey interactions is how a predator may respond to novel prey phenotypes, a form of frequency dependent prey selection. A predator may selectively target or avoid the novel prey, a behavior referred to as anti-apostatic or apostatic selection respectively. We examined apostatic prey selection by observing feeding behavior in two species of assassin bugs (Hemiptera: Reduviidae), the white-spotted assassin bug (Platymeris biguttatus) and the red-spotted assassin bug (Platymeris rhadamanthus) which were fed unmodified and modified (novel) phenotypes of Turkistan cockroaches, Blatta lateralis (Blattodea: Blattidae). The two species of assassin bugs represent either generalist (P. biguttatus) or specific feeders (P. rhadamanthus). We hypothesized that the generalist feeder would engage in anti-apostatic feeding while the specific feeder would engage in apostatic feeding. Our results indicated that there was no difference in feeding behavior between the two species, however an overall trend of apostatic feeding was observed in response to two of the four novel prey phenotypes. Factors beyond prey phenotype may also be influencing feeding choice in these insects. While the two predator species did not exhibit different feeding behaviors, the observation of apostatic feeding in this genus suggest an overall trend of utilizing specific prey images in feeding.
Experimental research procedure of roller forming unit
Authors: Loveikin Viacheslav , Pochka Kostiantyn , Balaka Maksym , Pochka Olha 
Published: December 2023

Experimental research is conducted followed by a comparative analysis of the results, which are obtained in the process of theoretical and experimental studies, to check the theoretical research adequacy of the roller forming unit with the crank drive.
We have developed the experimental research program for the roller forming unit with the crank drive. The research stand of roller forming with the crank drive was used for experimental studies. This research stand allows you to carry out full-value experimental studies on the determination of dynamic loads unrestricted. The experimental research program provides the determination of the interaction force for the compaction roller with the construction mixture, the force in the unit connecting rod, the torque on the unit drive shaft and the power, which is necessary for the realization of the forming process. The determination of these loads will make it possible to realistically assess the condition of the forming unit and rationally carry out its design and operation.
Plan, procedure and processing of experimental research data have been developed. The measuring and recording equipment were selected to determine the force loads of the research stand for conducting experimental studies, which transforms the received numerical data into Microsoft Excel for their processing. The measurement of the force in the connecting rod and the interaction vertical force of the compaction roller with the construction mixture was carried out using strain gauges. These are pasted according to the bridge scheme on the connecting rod and the metal plate, which is located in the form with the building mixture under the compaction roller. RK 435 universal clamps, which make it possible to measure the line voltage, the current strength and the power under unit different load modes, are used to measure the power required for the forming process.
PENGUKURAN TINGKAT KAPABILITAS TEKNOLOGI INFORMASI PADA SISTEM ADOVELIN WAREHOUSE INVENTORY SISTEM (AWIS)
Authors: Revansyah Ardho , Wedhasmara Ari , Sevtiyuni Putri Eka , Putra Apriansyah 
Published: December 2023

PT. Adovelin Raharja merupakan perusahaan yang menjadi solusi pengiriman dan logistik yang handal dengan menyediakan layanan tingkat tinggi dan standar dalam negeri dan internasional. Sebagai perusahaan yang menyediakan solusi pengiriman maka perusahaan sangat memperhatikan penggunaan box kontainer yang dicatat dalam suatu sistem informasi agar termonitoring dengan baik oleh perusahaan. Sistem informasi ini dinamakan Adovelin Warehouse Inventory System (AWIS). Ada tiga masalah pada sistem ini dan satu masalah pada tata kelola IT. Maka dari itu akan dilakukannya evaluasi sistem AWIS dan tata kelola TI menggunakan framework COBIT 5. Pada penelitian ini yang diukur yaitu capability level menggunakan metode Process Assessment Model dan Self Assessment. Domain proses yang dipilih berdasarkan masalah yaitu APO01, APO03, APO09, dan DSS01. Tingkat kapabilitas pada domain proses APO01 dan APO09 berada pada level 3, APO03 berada pada level 2, dan untuk DSS01 berapa pada level 4. Dari tingkat kapabilitas yang didapatkan akan diberikan rekomendasi perbaikan. Hasil dari pengukuran ini diharapkan dapat menjadi salah satu acuan rekomendasi perbaikan pada sistem AWIS.
Adovelin Raharja is a company that is a reliable shipping and logistics solution by providing a high level of service and domestic and international standards. As a company that provides shipping solutions, the company is very concerned about the use of container boxes that are recorded in an information system so that the company can monitor it properly. This information system is called Adovelin Warehouse Inventory System (AWIS). There are three problems with this system and one problem with IT governance. Therefore, an evaluation of the AWIS system and IT governance will be carried out using the COBIT 5 framework. In this study, the capability level was measured using the Process Assessment Model and Self Assessment methods. The process domains selected based on the problem are APO01, APO03, APO09, and DSS01. The capability level in the APO01 and APO09 process domains is at level 3, APO03 is at level 2, and for DSS01 what is at level 4. From the capability level obtained, recommendations for improvement will be given. The results of this measurement are expected to be a reference for recommendations for improvement in the AWIS system.
PREDIKSI PENJUALAN KOPI PADA PT. KOPI CAP LESUNG LUBUKLINGGAU MENGGUNAKAN METODE SINGLE MOVING AVERAGE (SMA)
Authors: Wulandari Cindi , Alamsyah M. Nur , Layla Layla 
Published: December 2023

The problem in this study is that it is difficult for PT. Kopi Cap Lesung to determine sales in the next period, because no one has predicted using the Single Moving Average (SMA). This study uses data collection methods by observing and recording directly at the research site (observation), conducting direct questions and answers to sources (interviews) and documentation by reading previous guidelines. The results of this study are the values ​​obtained for the next 3 years using the Single Moving Average method and for the error value MAD (Mean Absolute Deviation) Error Value of 25.280434782608694, Mean Square Error (MSE) Error Value of 10843.610677083334, and Error Mean Absolute Percentage Error (MAPE) of 5.638958229765874% less than 10% which obtained an accuracy rate of 95% which is implemented in the Python Programming Languagethat is google collab. which means the value is very good for predicting coffee sales. Keywords: Single Moving Average, Prediction, Python
PERBANDINGAN METODE WEIGHTED PRODUCT DAN PROFILE MATCHING DALAM PROMOSI JABATAN KARYAWAN PT.XYZ
Authors: Meiriza Allsela , Putra Pacu , Sevtyuni Putri  Eka , Mardiah Rani , Yunita Riska , Barata Gusti , Putra Apriansyah , Wedhasmara Ari , Oktadini Nabila Rizky 
Published: December 2023

Promosi jabatan merupakan suatu yang penting bagi jenjang karir seorang karyawan. Dengan mendapatkan promosi, maka karyawan tersebut dapat mengembangkan karirnya dari posisi sebelumnya. Saat ini PT. XYZ belum mempunyai metode pendukung keputusan yang tepat dalam penentuan promosi jabatan karyawan, sehingga menghasilkan keputusan subjektif, oleh sebab itu, penelitian ini bertujuan membantu PT. XYZ dalam menemukan metode pendukung keputusan yang tepat agar diperoleh keputusan yang objektif dengan melakukan perbandingan. Adapun metode yang dibandingkan yaitu metode weighted product dan profile matching. Pengujian menggunakan pendekatan confusion matrix. Hasilnya metode weighted product memiliki nilai lebih tinggi dari metode profile matching dalam tingkat akurasi 95%, presisi 100%, dan recall 75%.
Limited Preparedness: Challenges during Desert Locust Management in Kenya
Authors: Baraka Gachie Eliud , Sirera Ann Merecia , Ong’amo George Otieno 
Published: December 2023

Desert locust invasions could lead to serious food insecurity. However, effective and efficient management of the pest is usually faced with a myriad of constraints. This study sought to determine the challenges that Kenya faced during the 2019-2021 Desert locust management operations. The study used a mixed methods approach using ex-post facto evaluation and cross-sectional survey designs. The target population included Desert locust affected persons. Multi-stage stratified and purposive sampling were used to target a sample size of 900 respondents drawn from 30 counties that were affected by Desert locusts. Structured questionnaire and focus group discussion (FGD) were used to collect quantitative and qualitative data that was analysed through descriptive and inferential statistics as well as thematic review. The findings revealed that human resource and geographical challenges had 17% and 16% hindrance to Desert locust management, respectively. Technical and coordination challenges contributed 15% obstruction each; while financial limitations had 13% impediment. Political and sociocultural challenges contributed 12% hinderance each. The concludes that challenges during Desert locust management exacerbated human security risks from Desert locusts. The study recommends continuous capacity development through regular maintenance of equipment, continuous training of personnel and periodic update of preparedness plans.