bluuebunny/crossref_metadata_2025_split huggingface dataset:
Child Opportunity Index and Rehospitalization for Ambulatory Care Sensitive Conditions at US Children’s Hospitals
Authors: Parikh Kavita , Lopez Michelle A. , Hall Matt , Bettenhausen Jessica , Sills Marion R. , Hoffmann Jennifer , Morse Rustin , Shah Samir S. , Noelke Clemens , Kaiser Sunitha V. 
Published: October 2023

OBJECTIVE
Child Opportunity Index (COI) measures neighborhood contextual factors (education, health and environment, social and economic) that may influence child health. Such factors have been associated with hospitalizations for ambulatory care sensitive conditions (ACSC). Lower COI has been associated with higher health care utilization, yet association with rehospitalization(s) for ACSC remains unknown. Our objective is to determine the association between COI and ACSC rehospitalizations.

METHODS
Multicenter retrospective cohort study of children ages 0 to 17 years with a hospital admission for ambulatory care sensitive conditions in 2017 or 2018. Exposure was COI. Outcome was rehospitalization within 1 year of index admission (analyzed as any or ≥2 rehospitalization) for ACSC. Logistic regression models adjusted for age, sex, severity, and complex and mental health conditions.

RESULTS
The study included 184 478 children. Of hospitalizations, 28.3% were by children from very low COI and 16.5% were by children from very high COI neighborhoods. In risk-adjusted models, ACSC rehospitalization was higher for children from very low COI than very high COI neighborhoods; any rehospitalization occurred for 18.7% from very low COI and 13.5% from very high COI neighborhoods (adjusted odds ratio 1.14 [1.05–1.23]), whereas ≥2 rehospitalization occurred for 4.8% from very low COI and 3.2% from very high COI neighborhoods (odds ratio 1.51 [1.29–1.75]).

CONCLUSIONS
Children from neighborhoods with low COI had higher rehospitalizations for ACSCs. Further research is needed to understand how hospital systems can address social determinants of health in the communities they serve to prevent rehospitalizations.
Synthesis of highly-porous nitrogen-doped carbon materials by pyrolysis of melamine-formaldehyde resin using a hard template
Authors: Sinelnikova Yuliya , Nizovskii  Alexander , Uvarov Nikolai 
Published: October 2023

The use of nitrogen-doped carbon materials as electrodes in supercapacitors is a promising area of research. In this study highly-porous nitrogen-containing carbon materials were obtained by pyrolysis of melamine formaldehyde resin in the presence of nanocrystalline MgO as a hard template that was washed off after the pyrolysis. Magnesium citrate was used as a precursor for the synthesis of the template agent in situ during the pyrolysis of the resin. The obtained materials were characterized by X-ray diffraction, BET nitrogen adsorption method and Raman spectroscopy. The presence of nitrogen in the amount of 4 atomic percent was proved by XPS spectroscopy. The specific surface area was found to increase monotonically from 10 to 1300 m2/g with an increase in the content of magnesium citrate in the initial mixture. The samples showed high capacitance of 120 F/g in 1 M H2SO4 electrolyte and can be used in supercapacitors.
Performance Evaluation of the STANDARD F Strep A Ag FIA for the Diagnosis of Group A Streptococcal Pharyngitis
Authors: Seon A Jo  , Sang Hyuk Ma  , Seungjun Lee  , Sunjoo Kim  
Published: October 2023

Background: Pharyngitis is one of the most common conditions encountered in primary health care facilities. Accurate differentiation of group A streptococcus (GAS) infection from viral infection is difficult. The STANDARD F Strep A Ag FIA (SD BIOSENSOR, Korea) is a rapid antigen detection test (RADT) that has been recently developed for diagnosing GAS pharyngitis. In this study, we evaluated the diagnostic performance of the STANDARD F Strep A Ag FIA and compared the results between the RADT and conventional throat culture. Methods: Throat swab samples were obtained from a total of 372 children presenting pharyngitis symptoms in five pediatric clinics in Changwon, Korea from July 2018 to October 2019. A comparative study between STANDARD F Strep A Ag FIA and Sofia Strep A FIA (Quidel, USA) was performed. Two throat swabs were taken simultaneously from each patient for RADT. The third throat swab was stored in a transport tube containing Stuart’s transport medium for culture. Performance and kappa index of STANDARD F Strep A Ag FIA were evaluated. Results: GAS infection was detected in 29.3% (109/372) patients, using the STANDARD F Strep A Ag FIA. The sensitivity, specificity, positive predictive value, and negative predictive value were 95.0%, 95.2%, 88.1%, and 98.1%, respectively. The STANDARD F Strep A Ag FIA showed an excellent concordance rate of 96.5% and a kappa value of 0.89 compared to Sofia Strep A FIA. Conclusion: The STANDARD F Strep A Ag FIA demonstrated an excellent performance along with Sofia Strep A FIA for the diagnosis of GAS pharyngitis.
Evaluation of the Use of Distilled Water as a Sodium Hydroxide Wash in Antimicrobial Cultures
Authors: Hae-Gyeong Baek  , Hyun-Mi Ko  , Myung-Hee Lee  
Published: October 2023

Background: Respiratory specimens subjected to mycobacterial detection were initially pretreated with N-acetyl-L-cysteine-sodium hydroxide (NALC-NaOH) to remove the mucus and normal flora.Next, they were washed and neutralized with a phosphate-buffered solution (PBS). The effectiveness of distilled water (DW) compared to PBS as a washing neutralizer during the identification of mycobacteria was evaluated in this study. Methods: We analyzed the results of the mycobacterial test conducted at a general hospital in Gwangju from October 2016 to September 2018. PBS and DW were used as a respiratory sample-washing agent for one year each. Results:The positive culture rate for the culture of mycobacteria was 12.7% (1,843/14,532) and 14.7% (2,095/14,291), when PBS and DW were used, respectively. The recovery rate of the mycobacteria growth indicator tubes (MGIT) and the separation rates of the Mycobacterium tuberculosis complex and nontuberculous mycobacteria (NTM) showed no significant change. However, in the 2% Ogawa medium, as the NTM culture increased from 47.4% (399/841) to 56.1% (630/1,122),the recovery rate increased from 45.6% (841/1,843) to 53.6% (1,122/2,095). The MGIT contamination rate decreased from 6.5% to 4.1%. Conclusion: DW as a washing agent for NALC-NaOH increased the recovery rate of Ogawa medium and reduced the contamination rate of MGIT. Therefore, the use of DW instead of PBS as a washing neutralizer during the identification of mycobacteria might be useful.
Clinical Utility of SARS-CoV-2 Antibody Testing
Authors: Hyun Soo Kim  
Published: October 2023

SARS-CoV-2 antibody assay is a test that checks whether an antibody against the SARS-CoV-2 virus has been formed in the blood after SARS-CoV-2 infection or vaccination. SARS-CoV-2 antibody is detected 1–2 weeks after infection, and antibodies are produced in more than 90% of infected patients. The duration for the formation of antibodies differs by individual and by type of antibody. In the case of IgG, it is at least several months or longer, and the relationship between antibodies and immunity is being studied. As test methods,enzyme-linked immunosorbent assay (ELISA), chemiluminescence immunoassay (CIA), immunochromatographic assay, and neutralizing antibody assay have been developed and used. The target antibody to be detected differs depending on the type of recombinant antigen and the type of secondary antibody in reagents. Many kinds of commercialized SARS-CoV-2 antibody assays are currently being developed, and the S (spike) protein, N (nucleocapsid) protein, S1 or RBD (receptor binding domain) part of the S protein, and a mixture of these antigens are used as recombinant antigens of reagents. IgG, IgM, IgA, or total immunoglobulin antibodies in patients’ blood that react with these reagent antigens are detected. In this review, the types and performance of SARS-CoV-2 antibody tests and the guidelines for COVID-19 antibody tests published domestically and abroad were investigated.
Bike-sharing: the good, the bad, and the future
Authors: Duran-Rodas David , Villeneuve Dominic , Wulfhorst Gebhard 
Published: October 2023

Due to the dilemma of bike-sharing concerning its benefits and drawbacks, and its unclear future, we focused on a mixed-methods approach to analyze this public discussion through posts or “tweets” from the social media channel Twitter. We collected around 12,000 tweets in English around the world related to bike-sharing for a period of about six months. We considered two approaches, including topic clustering and sentiment analysis in tweets including: a) bike-sharing related terms and b) “future” and bike-sharing related terms. Strongly positive tweets promote bike-sharing and its benefits such as being convenient, well-performing, and sustainable. Additionally, there is a tendency to write that public, electric, and dockless are better, together with scooters. In contrast, the complaints on bike-sharing focused on inequity, rentals and safety issues, critique on authorities and laws, and poor performance especially of dockless Asian bike-sharing start-ups with low-quality bikes. Around 50% of the tweets that included the terms “future” and “bike–sharing” stated that bike-sharing is going to be part of the future of mobility as an electric dockless version together with other shared modes. The hesitant statements towards bike-sharing being part of the future referred mainly to the systems with poor bikes’ quality. Politicians and stakeholders can use this information to enhance bike-sharing or consider the implementation of certain types of bike-sharing in their cities. To the best of the authors’ knowledge, this study would be one of the first that analysis the public discussion on social media about a transportation system and its future using a mixed-methods approach. Future studies should aim at identifying and comparing the public opinion of different emerging transportation technologies.
Airport classification in Chinese multi-airport regions
Authors: Chen Yuting , Fuellhart Kurt , Zhang Shengrun , Witlox Frank 
Published: October 2023

The agglomeration of airports into multi-airport regions (MARs) has become one of the salient features of the worldwide air transport system in the last decades. Meanwhile, in China, the development of HSR is growing quickly, and is both competitive to and cooperative with the aviation network. To date some research has focused on the airport classification with aviation network properties within the specific MARs. However, little research comprehensively integrates complementary transport systems (such as civil aviation versus high-speed rail (HSR)) into the analytical framework for airport classification. The purpose of this paper is to identify the unique nature of component airports and their distribution in MARs in China from multiple perspectives by accounting for the influence of the HSR system. Airports are classified along multiple dimensions including competitive concentrations, the interaction between air transport and HSR, and airport community structure, among others. The results produce distinct partitions of the component airports in Chinese MARs, and provide insights into Chinese airport functionality and impacts of the HSR network on the distribution of different types of airports. The conclusions provide a more comprehensive assessment of airports’ spatial arrangement in the unique Chinese MAR context. Although this paper did not derive the market share allocation and co-opetition relationship between a specific airport and HSR, it proposed a basic framework for future research.
Travel time, delay and CO2 impacts of SAE L3 driving automation of passenger cars on the European motorway network
Authors: Aittoniemi Elina , Itkonen Teemu , Innamaa Satu 
Published: October 2023

Impacts of driving automation on traffic flow and emissions are usually studied with traffic simulations using only few speed limits and traffic volumes. Without considering the real-world prevalence of simulated scenarios, it is unknown how the results translate to real-world conditions, such as a regional motorway network. The present study assessed the potential impacts of conditionally automated driving, described by stable vehicle motion control and longer time gaps, on the European motorway network assuming no changes in other influential factors, such as travel demand or vehicle fleet. Traffic simulations provided estimates of the effect magnitude per vehicle kilometre travelled (VKT) in representative conditions, and results were scaled up using map-, traffic- and weather-related data, accounting for the VKT per condition. Overall, the impacts of automated vehicles (AVs) on the European motorway network are likely small. Travel times and delay are estimated to increase by 0.8% and 1.3% respectively at a 100% AV penetration rate among passenger cars, and CO2 emissions to drop by 0.5%. While large reductions of average travel time (up to 8.0–10.4%), delay (up to 17.5–34.8%) and emissions (up to 13.5–15.0%) were found at high traffic volumes, most (86%) of the VKT accumulate at low traffic volumes, with small estimated effects. Thus, although beneficial in some conditions, the AVs considered in this study are not likely to support Europe’s sustainability goals. Findings advocate a comprehensive approach: Whereas impacts are likely greatest in heavy traffic, the prevalence of conditions must be considered in network level assessment.
Women’s Experiences of Perinatal Anxiety: A Critical Feminist Approach
Authors: Powell Zalia , Harris Nonie , Francis Abraham 
Published: October 2023

OBJECTIVE:Perinatal anxiety is a prevalent mental health issue with implications for the well-being of women and their children. There is a scarcity of research that considers perinatal anxiety as a standalone mental health issue or explores the lived experiences of women with perinatal anxiety.METHODS:In-depth interviews were carried out with nine mothers who had a lived experience of perinatal anxiety. The women were recruited from South East Queensland, Australia, and were either pregnant and/or parenting a child under the age of five. Data from the interviews were analyzed through a process of thematic analysis to identify key themes in the lived experiences of anxious mothers. Critical feminist theory informed all the aspects of the study.RESULTS:Analysis of the data revealed four key themes: Good Motherhood, Warning Signs, Mental Health Literacy, and Strengths and Support, and seven subthemes: The Birthing Experience, Irritable Infants, Sleep, Breastfeeding, Social Isolation, Barriers to Help Seeking, and Social Roles. Anxiety was found to complicate the experience of motherhood, with the pressure to present as a “good mother” resulting in a reluctance to seek help. Experiences such as birthing, feeding, and sleeping were risk factors for triggering or exacerbating anxiety. Experiences of perinatal anxiety were further complicated by poor mental health literacy and inconsistencies in the care provided by health professionals. Anxious mothers expressed a need for holistic, multidisciplinary mental healthcare, with residential options during times of struggle or crisis.CONCLUSION:Findings reveal the complex context of motherhood and mental illness and identify barriers and opportunities for the multidisciplinary mental healthcare of anxious mothers. A holistic, multidisciplinary response to perinatal anxiety is recommended.
Hepatocellular carcinoma cell-derived small extracellular vesicle-associated CD147 serves as a diagnostic marker and promotes endothelial cell angiogenesis via the PI3K/Akt pathway
Authors: Huang De-Fa , Zhang Wen-Juan , Chen Jie , Jiao Zhi-Gang , Wang Xiao-Ling , Rao Ding-Yu , Li Wei-Song , Hu Die , Xie Fang-Fang , Wang Xiao-Xing , Li Zheng-Zhe , Yi Xiao-Mei , Wu Ji-Yang , Jiang Yu , Wang Qi , Zhong Tian-Yu 
Published: October 2023

Aim: Hepatocellular carcinoma (HCC) is one of the most common malignant tumors. The process of HCC development is closely related to angiogenesis. Plasma exosomes have diagnostic value in many diseases and have become a current research hotspot. We aimed to identify a key molecule in small extracellular vesicles (sEVs) involved in angiogenesis as a diagnostic marker for HCC and uncover the mechanism underlying its regulation in the angiogenesis process.
Methods: Nano‐flow cytometer (nFCM) was used to detect CD147 expression in plasma-derived sEVs in 155 HCC patients, 59 liver cirrhosis (LC), and 82 healthy donors (HD). The mechanism of hepatocellular carcinoma cell-derived sEVs CD147 promoting angiogenesis was elucidated by cell proliferation assay, scratch wound healing assay, transwell assay, tube formation assay, and in vivo Matrigel plug angiogenesis assay.
Results: We found that CD147 expression was significantly higher in HCC tissue samples than in normal tissues. We also found a significantly larger number of CD147-positive small extracellular vesicles (CD147+ sEVs) in the plasma of HCC patients than LC patients and HD. Furthermore, we showed that hepatocellular carcinoma cell (HepG2)-derived CD147+ sEVs promoted cell proliferation, migration, invasion, and angiogenesis in human umbilical vein endothelial cells. The CD147+ sEVs upregulated vascular endothelial growth factor A (VEGFA) by activating the PI3K/Akt pathway, thereby promoting angiogenesis.
Conclusion: HCC-derived sEVs-associated CD147 serves as a diagnostic marker and promotes endothelial cell angiogenesis via the PI3K/Akt pathway.
Program PERMATA BUNDA sebagai Upaya Pencegahan dan Penurunan Stunting di Kabupaten Barito Kuala
Authors: Wijaya Candra 
Published: October 2023

Stunting merupakan masalah kesehatan yang berkaitan dengan peningkatan risiko keluhan, kematian serta hambatan pada masa pertumbuhan baik itu dari motorik maupun mental. program PERMATA BUNDA (Pemberian Makanan Tambahan Bagi Ibu Hamil dan Anak Balita) adalah salah satu upaya pemenuhan zat gizi spesifik dalam rangka mendukung 1000 Hari Pertama Kehidupan dan pemenuhan Standar Pelayanan Minimal Bidang Kesehatan, terutama untuk ibu hamil, bayi dan balita, serta mendorong terwujudnya generasi Barito Kuala yang tumbuh sehat dan bebas stunting. Hasil yang didapatkan dari implementasi PERMATA BUNDA dibutuhkan komitmen dan dukungan dari pemangku kebijakan, agar kebersinambungan manfaatnya dapat terus dirasakan masayarakat, karena Program PERMATA BUNDA terbukti dapat menurunkan kasus stunting di Barito Kuala, yaitu 16,86% pada tahun 2020 menjadi 12,56% pada tahun 2022 berdasarkan data ePPBGM tahun 2022. Kata Kunci: Permata Bunda; Stunting; Barito Kuala Stunting is a health problem associated with an increased risk of complaints, death, and obstacles during the growth period, both motor and mental. The PERMATA BUNDA program (Providing Supplementary Food for Pregnant Women and Toddlers) is one of the efforts to meet specific nutrition needs in order to support the First 1000 Days of Life and meet Minimum Service Standards in the Health Sector, particularly for pregnant women, infants, and toddlers, as well as encourage the creation of a new generation of Barito Kuala that are growing healthy and free of stunting. The Permata Bunda program is funded through budget synergy from the Village Community Empowerment Service for making ready-to-eat food menus for non-Chronic Energy Deficiency (KEK) pregnant women and undernourished toddlers, while for pregnant women and toddlers with KEK, the budget source is Health Operational Costs at the Health Center. The implementation of PERMATA BUNDA requires commitment and support from stakeholders, so that the benefits can continue to be felt by the community, because the PERMATA BUNDA Program has been proven to be able to reduce stunting cases in Barito Kuala, namely from 16.86% in 2020 to 12.56% in 2022 based on data from ePPBGM in 2022.
Edukasi “Bijak Menyikapi Issue Penggunaan Obat Sirup bagi Anak” kepada Kader Posyandu di Wilayah Kerja Puskesmas Landasan Ulin
Authors: Safitri Nita , Intannia Difa , Lingga Herningtyas Nautika , Muftadi Imam , Ratnapuri Prima Happy 
Published: October 2023

Posyandu adalah tempat pelayanan kesehatan masyarakat dalam hal peningkatan status gizi masyarakat, kesehatan ibu dan anak sebagai upaya preventif dan promotif. Permasalahan isu adanya sirup obat yang mengandung etilen glikol dan dietilen glikol meresahkan ibu-ibu karena menyebabkan terjadinya gagal ginjal akut untuk anak-anak. Program promosi kesehatan ini bertujuan untuk memberikan edukasi, informasi dan pengetahuan terkait isu cemaran pada sirup obat kepada kader posyandu. Metode yang dilaksanakan yaitu penyuluhan secara langsung melalui presentasi dan diskusi interaktif, disertai dengan pembagian leaflet kepada 25 kader posyandu di wilayah kerja Puskesmas Landasan Ulin. Hasil dari program yang dilakukan peserta adalah peserta memiliki pemahaman yang lebih baik dan komprehensif terkait isu cemaran sirup sehingga dapat menyampaikan kembali informasi yang diperoleh kepada masyarakat di lingkungan agar lebih bijak dalam menyikapi berbagai isu cemaran sirup yang beredar. Kata Kunci: Cemaran, Dietilen Glikol, Etilen Glikol, Leaflet, Penyuluhan. Posyandu is a public health service ceter in terms of improving nutritional status of the community, maternal and child health as a preventif and promotive effort. The issue of the existence of medicinal syrup containing ethylene glycol and diethylene glycol disturbs mothers because it causes acute kidney failure in children. This health promotion program aims to provide education, information and knowledge related to the issue of drug syrup contamination to posyandu activists. The method implemented was direct education through presentations and interactive discussions, accompanied by leaflet distribution to 25 posyandu activists in the Landasan Ulin Health Center area. The result of the program carried out by participants is that the participants have a better and comprehensive understanding of the issue of syrup contamination so that they can convey the information obtained to wider community in the Landasan Ulin Health Center area, so that they are wiser in responding to various issues of syrup contamination.
Uji Efektivitas Serbuk Cangkang Keong Mas plus Trichoderma spp. terhadap serangan Nematoda Puru Akar (Meloidogyne spp.) Pada Tanaman Seledri (Apium graveolens L.)
Authors: Imani Tegar , Liestiany Elly , Aidawati Noor 
Published: October 2023

Seledri (Apium graveolens L.) merupakan tanaman budidaya yang memiliki aroma khas serta bernilai ekonomis tinggi dan potensial untuk dikembangkan di Indonesia. Salah satu organisme pengganggu tumbuhan (OPT) yang dapat mempengaruhi kualitas serta kuantitas dari produksi seledri adalah nematoda puru akar yang disebabkan oleh Meloidogyne spp. Penelitian ini bertujuan untuk mengetahui efektivitas serbuk cangkang keong mas plus Trichoderma spp. dalam mempengaruhi serangan nematoda puru akar (Meloidogyne spp.) pada tanaman seledri (A. graveolens L.). Penelitian ini dirancang menggunakan Rancangan Acak Lengkap (RAL) satu faktor. Faktor yang diujikan adalah pengaruh pemberian serbuk cangkang keong mas plus Trichoderma spp., pemberian serbuk cangkang keong mas dan pemberian Trichoderma spp. Ada 6 perlakuan dan 4 ulangan dengan parameter pengamatan yaitu intensitas serangan, populasi nematoda, jumlah tangkai dan berat basah tanaman seledri. Hasil penelitian menunjukkan bahwa pemberian serbuk cangkang keong mas plus Trichoderma spp. dapat mempengaruhi intensitas serangan puru akar dan mengurangi populasi nematoda ditanah sekitar perakaran, serta berpengaruh nyata pada jumlah daun (tangkai) dan berat basah tanaman seledri.