bluuebunny/crossref_metadata_2025_split huggingface dataset:
Zinc-dependent Nucleosome Reorganization by PARP2
Authors: Maluchenko Natalya , Saulina Alexandra , Geraskina Olga , Kotova Elena , Korovina Anna , Feofanov Alexey , Studitsky Vasily 
Published: October 2023

AbstractPoly(ADP-ribose)polymerase 2 (PARP2) is a nuclear protein that acts as a DNA damage sensor; it recruits the repair enzymes to a DNA damage site and facilitates formation of the repair complex. Using single particle Förster resonance energy transfer microscopy and electrophoretic mobility shift assay (EMSA) we demonstrated that PARP2 forms complexes with a nucleosome containing different number of PARP2 molecules without altering conformation of nucleosomal DNA both in the presence and in the absence of Mg2+or Ca2+ions. In contrast, Zn2+ions directly interact with PARP2 inducing a local alteration of the secondary structure of the protein and PARP2-mediated, reversible structural reorganization of nucleosomal DNA. AutoPARylation activity of PARP2 is enhanced by Mg2+ions and modulated by Zn2+ions: suppressed or enhanced depending on the occupancy of two functionally different Zn2+binding sites. The data suggest that Zn2+/PARP2-induced nucleosome reorganization and transient changes in the concentration of the cations could modulate PARP2 activity and the DNA damage response.Significance StatementPARP2 recognizes and binds DNA damage sites, recruits the repair enzymes to these sites and facilitates formation of the repair complex. Zn2+-induced structural reorganization of nucleosomal DNA in the complex with PARP2, which is reported in the paper, could modulate the DNA damage response. The obtained data indicate the existence of specific binding sites of Mg2+and Zn2+ions in and/or near the catalytic domain of PARP2, which modulate strongly, differently and ion-specifically PARylation activity of PARP2, which is important for maintaining genome stability, adaptation of cells to stress, regulation of gene expression and antioxidant defense.
Impact of digital capabilities of countries on the pedagogical transitions in business schools
Authors: Pandya Bharti , Cho BooYun , Patterson Louise 
Published: October 2023

Purpose
During the COVID-19 pandemic, the importance of digital infrastructure in higher education surged. This study aims to analyze how a country’s digital capabilities influence pedagogical transitions in business schools and compare the impacts between digitally advanced and advancing countries.

Design/methodology/approach
The authors applied the job demands–resources model and the IMD World Digital Competition Ranking 2021 to analyze the impact of nations’ digital capabilities on the pedagogical transitions experienced by 121 business faculty members from 20 nations. The countries were categorized into digitally advanced countries and advancing countries. The snowball sampling method was used to gather data through an online survey consisting of 24 items. SPSS was used to statistically analyze the data in two stages using paired t-test and group comparison.

Findings
Significant shifts between face-to-face and online lectures occurred in both groups. Advanced countries witnessed positive shifts in discussions, presentations, oral assessment, independent learning opportunities, online teaching methods, technical support and faculties’ readiness, whereas advancing countries mainly noted alterations in professional development and communication technologies.

Originality/value
This study offers insights into optimizing digital capabilities and enhancing business schools’ readiness for effective pedagogical shifts during crises. Both the theoretical contribution and the findings will benefit national education policies, higher education institution leaders, scholars and educators.
Gender, external financing and firm performance: evidence from Chinese private firms
Authors: Huang Lingyun , Liu Jiankun , Huang Zhigang 
Published: October 2023

PurposeThe operational framework of external financing in the correlation between the gender of entrepreneurs and firm performance remains to be resolved. This study aims to investigate the mediating effect of external financing on gender-based disparities in private firm performance and to explore its heterogeneity within the Chinese context.Design/methodology/approachBased on national data from the 10th to 13th Chinese Private Enterprise Survey, this study used a bootstrap-based mediation effect model to analyze the role of external financing as a mediator in the relationship between entrepreneur gender and firm performance.FindingsThis study found that external financing is a constructive mediator between entrepreneur gender and firm performance. Heterogeneity analysis revealed that external financing plays a complementary mediation role in the impact of entrepreneur gender on performance in West China. In the tertiary industry, external financing acts as the sole mediator for the impact of gender on firm performance. Notably, this mediating effect is present in non-startups but not in startups.Practical implicationsThe findings suggest that external financing can improve the firm performance of female entrepreneurs. Governments and policymakers should strengthen financial support for female entrepreneurs in West China, tertiary industry and non-startup enterprises.Originality/valueThis paper contributes to the literature on gender and corporate governance by shedding light on the mediating role of external financing in the relationship between the gender of business owners and firm performance.
The influences of psychosocial work environment on the turnovers of civil service cadre officers in rural Bangladesh: an empirical study
Authors: Huynh Thanh , Sheikh Md Mahabur Rahman 
Published: October 2023

PurposeThe purpose of this study is to determine the effects of the psychosocial work environment on the turnover of civil service cadre officers in rural areas in Bangladesh.Design/methodology/approachPhysical intimidation, mental health and well-being, organisational impediments, decision latitude, psychological job demands and social interaction were developed as variables to examine in relation to job satisfaction and turnover. This study gathers 406 responses from Bangladesh Civil Service (BCS) cadre officers in rural areas to test the hypotheses.FindingsThe findings indicate that physical intimidation increases employee turnover, whereas psychosocial job demand decreases it. Physical intimidation reduces job satisfaction, whereas decision flexibility and social interaction enhance job satisfaction, hence reducing the turnover of civil service cadre officers in rural Bangladesh.Originality/valueThis research contributes to the creation of context-specific and targeted public sector support, particularly the interventions and policies addressing the work environment in rural areas.
Adopting blockchain-based traceability in the fruit supply chain in a developing economy: facilitators and barriers
Authors: Yap Teck Lee , Nayak Rajkishore , Vu Nhung T.H. , Bui Duy Tung , Pham Thi Thu Tra , Allen Darcy W.E. 
Published: October 2023

PurposeBlockchain-based traceability technology (BTT) is an emerging digital technology that claims to have the potential to fulfil the demand for traceability to safeguard fruit safety. Drawing on the technological, organisational and environmental (TOE) framework, this study aims to investigate the perceived facilitators and barriers that influence the behavioural intentions of multiple stakeholders in the Vietnamese fruit supply chain (i.e., farmers, trading enterprises and consumers) to adopt BTT.Design/methodology/approachThis study utilised a qualitative approach of semi-structured in-depth interviews with 60 stakeholders in the Vietnamese fruit supply chain to achieve the research objectives. NVivo 12 was employed to analyse the collected data using content and thematic analysis.FindingsThe findings identify several perceived facilitators that motivate BTT adoption. These include trust, transparency, business performance, the formation of alliances, consumer awareness of food safety and ethical agricultural practices, fruit branding and the pivotal role of farmers' cooperatives. Meanwhile, the perceived barriers to BTT adoption include a lack of digital literacy amongst the stakeholders, poor organisational culture, the high cost of traceability-enabled products and data privacy and security governance.Practical implicationsThis study suggests that technology awareness and perceived facilitators and barriers should be incorporated into the design and deployment of blockchain-based traceability technology in the agri-food supply chain in developing countries.Originality/valueTo the best of the authors' knowledge, this study is the first qualitative paper that attempts to fill the research gap of understanding the perceived facilitators and barriers that influence the intentions of multiple stakeholders in the fruit supply chain to adopt BTT in the context of a developing economy.
Assessing the impact of business simulation as a teaching method for developing 21st century future skills
Authors: Sheikh Riyaz Abdullah , Abdalkrim Gaafar Mohamed , Shehawy Yasser Moustafa 
Published: October 2023

PurposeHigher education institutions are undergoing a change in their teaching–learning practices, with the core goal of giving students the necessary skills and competencies to succeed in a complex and uncertain society. This study aims to evaluate the effectiveness of business simulation as a pedagogical strategy for teaching 21st-century competencies to undergraduate students. The study looks at students’ self-perception on how business simulation impacts future skills such as entrepreneurship, employability and sustainability.Design/methodology/approachThe research incorporates a one-week workshop for undergraduate business students using AnyLogic business simulation. For this study, a 24-item skills-based survey was used as the instrument for eliciting input about students’ self-perceptions. To measure the impact of business simulation on overall student learning, a theoretical framework was developed and tested using SmartPLS version 4 for construct reliability, validity and hypotheses testing.FindingsBased on the students’ feedback, the finding shows that most of the 24 soft skills were facilitated by the business simulation used. The simulation significantly affects the development of entrepreneurial and employable skills. On the contrary, it has little effect on enhancing sustainability skills. In addition, the study suggests that factors like gender and expertise had little overall impact on the results.Practical implicationsThe most apparent practical implication of this study is that business schools should focus more on skill development by stressing on experiential teaching methods like business simulation to help students build various skills and become more prepared for the actual world of business.Originality/valueThe research presents fresh empirical data that add to the continuing discussion on active learning in business education and assist educators in avoiding some potential drawbacks of these innovative teaching techniques. With the right direction and criticism throughout the simulation, this learning experience has shown to be useful for everyone involved.
A mathematical model for erosive abrasive wear analysis by using abrasive size and material hardness
Authors: Kosa Ergin , Gökşenli Ali 
Published: October 2023

PurposeErosion and abrasion are the prominent wear mechanisms reducing the lifetime of machine components. Both wear mechanisms are playing a role meanwhile, generating a synergy, leading to a material removal on the target. The purpose of study is to create a mathematical expression for erosive abrasive wear.Design/methodology/approachMany factors such as environmental cases and material character have an influence in erosive abrasive wear. In the work, changes in abrasive size and material hardness have been analyzed. As an abrasive particle, quartz sand has been used. All tests have been done in 20 wt.% slurry. Heat treatment has been applied to different steel specimens (steel grades C15, St 37 and Ck45) to change hardness value, which ranged from 185 to 880 Vickers hardness number.FindingsAfter the four-hour test, it is determined that by an increase in abrasive size and decrease in material hardness, wear rate increases. Worn surfaces of the targets have been examined to figure out the wear mechanisms at different conditions under scanning electron microscopy. The results indicate that by an increase in material hardness, the number and diameter of micro-craters on the worn surfaces decrease. The diameters of micro-craters have been about 3–8 µm in hard materials and about 120–140 µm in soft materials.Research limitations/implicationsIt is determined that by an increase in abrasive size and decrease in material hardness, wear rate increases. The results indicate that by an increase in material hardness, the number and diameter of micro-craters on the worn surfaces decrease.Practical implicationsThe study enables to indicate the dominant factor in worn steel used in mechanical components.Originality/valueAfter analyzing the test results, a novel mathematical expression, considering both abrasive size and material hardness, has been developed.
Agencification, policy reversal and the reforms of the French health care system
Authors: Simonet Daniel 
Published: October 2023

PurposeOften linked to the New Public Management (NPM) doctrines, agencification has been on the priority list of policy makers for over two decades. This article proposes an analysis of the role of agencies in the French health system and the impact of government agency reform on physicians and the public.Design/methodology/approachThe research analyzes the perceived implementation of a re-concentration of decision-making powers within public agencies as the declared goal of agencification at the French health care system, specifically primary care providers and hospitals. The assessment relies on secondary sources from ministerial bodies such as the Ministry of Health and Social Affairs, the Ministry of Labor, the Social Security and the General Accounting Office, and specialized French technical agencies.FindingsDecentralization in France and the subsequent rise of public health care agencies had outcomes below expectations. Hence, a re-concentration of decision-making powers within the larger Regional Health Agencies; a streamlining of the public administration; and a re-appropriation of decision-making powers by the Ministry of Health are needed. The monitoring of health providers allows central health authorities to govern at a distance.Originality/valueThe analysis of health care agencies in France and of their use of efficiency-enhancing techniques may trigger a change of values within the medical profession.
Factors influencing the adoption of cryptocurrency in Bangladesh: an investigation using the technology acceptance model (TAM)
Authors: Islam Hasibul , Rana Masud , Saha Shimanto , Khatun Taslima , Ritu Mustari Rahman , Islam Md. Rashidul 
Published: October 2023

PurposeUsing the technology acceptance model (TAM), this study investigates factors influencing the adoption of cryptocurrency in Bangladesh.Design/methodology/approachData were collected from 346 members of the general public through a structured web survey using snowball sampling. Structural equation modeling was used to analyze the data and assess the reliability and validity of the measurement model.FindingsThe results show that knowledge of cryptocurrency, benefits of use (perceived usefulness), attitude and challenges all have a significant impact on the adoption of cryptocurrency.Research limitations/implicationsThis study was conducted in a single country, relied on self-reported data and used a cross-sectional design, which limits the ability to draw causal inferences. Future research could explore the factors that influence the adoption of cryptocurrency in different countries and regions and incorporate additional variables to provide a more comprehensive understanding of the drivers of intention to use cryptocurrency.Originality/valueThis study contributes to understanding the factors driving the adoption of and intention to use technology-based services, providing insights that can inform the design and implementation of future technology-based services.
Resistance risk assessment of six pyrethroids and acephate toward the resistant adult tarnished plant bug, Lygus lineolaris
Authors: Du Yuzhe , Scheibener Shane , Zhu Yucheng , Portilla Maribel , Zhang Mingling 
Published: October 2023

AbstractDue to rapidly developed resistance, pest management relies less on pyrethroids to control economically damaging infestations of the tarnished plant bug (TPB), Lygus lineolaris (Palisot de Beauvois) in cotton fields of Mississippi. Yet, pyrethroid resistance remains prevalent in TPB populations. This study assessed the resistance levels in adult TPB to six common pyrethroids and acephate. Resistant TBPs were collected from wild host plants in late October after harvest in the Mississippi Delta region of the United States. Based on LC50 values, the field‐resistant TPBs displayed higher resistance to permethrin, esfenvalerate, and bifenthrin (approximately 30 fold) and moderate resistance to λ‐cyhalothrin, β‐cyfluthrin, ζ‐cypermethrin, and acephate (approximately 15 fold). Further investigations showed that the inhibitors of three detoxification enzyme, triphenyl phosphate (TPP), diethyl maleate (DEM), and piperonyl butoxide (PBO) had synergistic effects on permethrin, λ‐cyhalothrin, and bifenthrin in resistant TPBs. Furthermore, elevated esterase, GST, and P450 activities were significantly expressed in field‐resistant TPBs. Additionally, GST and esterase were reduced after 48 h exposure to certain pyrethroids at LC50 dose. The synergistic and biochemical assays consistently indicated that P450 and esterase were involved in pyrethroid detoxification in TPBs. This study provides valuable information for the continued use of pyrethroids and acephate in controlling TPBs in cotton fields in the Mississippi Delta region of the United States.
Counting the ‘Cavaliers’: Two Contemporary Analyses of the Political Wing of the Scots Jacobite Underground in the Union Parliament1
Authors: Szechi Daniel , Whatley Christopher A. 
Published: October 2023

AbstractUnderground movements are understandably reluctant to record the names and numbers of their adherents because any such compilation is manifestly a hostage to fortune. Hence very few lists of politically active Jacobites actually compiled by the Jacobites themselves have survived to the present day. In the French foreign ministry archives at La Corneille, however, there is a rare and previously unknown/unused example of such a list. ‘The Rolls of Parliament as they stand’, is a classic printed, marked list of all the lords entitled to sit in, and commissioners elected to, Queen Anne's Union Parliament. It identifies the political allegiances of the great majority of the sitting commissioners and peers, and in particular the Jacobites among them. Rather better known, yet hitherto seldom consulted or used, is a debriefing document describing the political alignment of a great many of those in parliament and the general political inclination of their constituents written by Captain Harry Straton for the Jacobite King James III and VIII in August 1706. These two sources are the basis of the analysis that follows. The focus is on what these two Jacobite analyses of the state of Scotland and Scottish politics can tell us about the political dynamics of the Scottish Parliament and the country more broadly on the eve of the Union debates.
Disclosure and pricing of attributes
Authors: Smolin Alex 
Published: October 2023

AbstractA monopolist sells an object characterized by multiple attributes. A buyer can be one of many types, differing in their willingness to pay for each attribute. The seller can provide arbitrary attribute information in the form of a statistical experiment. To screen different types, the seller offers a menu of options that specify information prices, experiments, and object prices.I characterize revenue‐maximizing menus. All experiments belong to a class of linear disclosure rules. An optimal menu may be nondiscriminatory. The analysis highlights the importance of demand microstructure and the benefits of information control in trade settings.
Conocimiento de las comunidades de escarabajos que habitan el suelo en los Andes tropicales: Lagunas y tendencias
Authors: López‐Bedoya Pablo A. , Magura Tibor , Méndez‐Rojas Diana M. , Noriega Jorge Ari , Horgan Finbarr G. , Edwards David P. 
Published: October 2023

ResumenLos Andes tropicales son una de las ecorregiones más biodiversas de la Tierra, con altos niveles de endemismo de especies. Los Andes tropicales son también una de las ecorregiones más vulnerables del mundo debido a una larga historia de transformaciones antropogénicas. Uno de los principales obstáculos para generar planes de conservación son las lagunas en el conocimiento sobre el estado y las amenazas de muchos grupos de la biodiversidad andina, especialmente los invertebrados. Centrándonos en tres importantes grupos de escarabajos (Coleoptera: carábidos, estafilínidos y escarabajos estercoleros) de los Andes tropicales, realizamos una revisión sistemática de la literatura científica recuperando 50 estudios que nos permitieron evaluar el grado de conocimiento en la región, los tipos de perturbación y las métricas de biodiversidad utilizadas. Encontramos una alta representación de estudios en Colombia, en comparación con otros países andinos. También encontramos un marcado sesgo entre los grupos taxonómicos, los temas o las métricas evaluadas, siendo los escarabajos estercoleros el grupo más representado, especialmente en los estudios que abordan la conversión de los bosques utilizando métricas como la riqueza de especies o la abundancia. Revelamos grandes lagunas en la información sobre la diversidad de los escarabajos del suelo y de los roedores, y en el uso de otras métricas de diversidad. La falta de información en todos los países dificulta la generalización de los resultados y resalta la necesidad de más investigación, especialmente en países poco representados como Bolivia y Venezuela. La inclusión de métricas de respuesta complementarias, como la biomasa, la diversidad funcional o las funciones ecológicas, mejorará la evaluación de los impactos humanos en las comunidades de escarabajos andinos tropicales y en ecosistemas más amplios.
Influence of two kinematics on canal transportation and centering ability of WaveOne Gold and One Curve files
Authors: Almazedi Raghda A. K. , Al‐Zaka Iman M. 
Published: October 2023

AbstractThis research examines canal transportation and centering ability of single‐file systems when operated in continuous rotation or reciprocation. Sixty J‐shaped resin blocks were used. The specimens were divided into two main groups (n = 30). Then, based on the motion used to operate the instruments, each group was subdivided into two subgroups (n = 15). Group A1: One Curve/rotation, Group A2: One Curve/clockwise reciprocation, Group B1: WaveOne Gold/Reciprocation, Group B2: WaveOne Gold/counter‐clockwise rotation. Pre‐ and post‐instrumentation images were obtained using digital microscope. Canal transportation was measured at five levels. A non‐significant difference (p > 0.05) resulted between two motions at all levels. However, group A1 showed significantly less transportation at levels 3 and 4 (p ≤ 0.05), also more centered preparation at level 4 (p ≤ 0.05) than group B1. Within the limitations of this study, the apical transportation and centering ability of single‐file systems are unaffected by different kinematics.