bluuebunny/crossref_metadata_2025_split huggingface dataset:
A New Advanced Osteoarthritis Treatment Utilizing Modified Mesenchymal Stem Cells: Arthroscopic Guided Intra-Articular Intervention Approach a Systematic Review and Meta-Analysis
Authors: Tjandra Kevin Christian , Novriansyah Robin , Ar Ardiyana , Rahmawati Nurul Azizah Dian , Sudiasa I Nyoman Sebastian , Dilogo Ismail Hadisoebroto 
Published: December 2023

AbstractBackgroundThe mesenchymal stem cells (MSCs) is able to regenerate the cartilage defect caused by osteoarthritis (OA) to prevent permanent disability. Its efficacy may be even greater in combination with platelet-rich plasma (PRP) and hyaluronic acid (HA). Thus, this systematic review aimed to investigate the efficacy of MSCs in combination with PRP and adjusted doses of HA, the best source of MSCs, and the optimal number of applied MSCs to treat osteoarthritis as a cartilage regenerative agent.MethodThe sources included were original articles published from 2013 until 2023 from 4 databases (Pubmed, Springerlink, ScienceDirect, and Google Scholar). Studies included were original research of clinical trials or randomized controlled trials. Irrelevant studies were excluded. Then, the ROB-2 taken was used to assess bias. The result was constructed with PICOS criteria within the table created in the Google spreadsheet. MRI score, VAS score, Lysholm score, Cartilage volume, size of cartilage defect, Knee Society Clinical Rating System Score (KSS),and WOMAC index to evaluate treatment’s effication outcomes were analyzed by Revman 5.4. This systematic review followed the PRISMA guidelines.Resultnine studies were included in the final screening. The meta-analysis showed a significant (P < 0.00001) elevation of Lysholm score with a pooled mean difference (MD) of (17.89) (95% CI: 16.01, 19.77; I2= 0%, P = 0.56); a significant reduction (P < 0.00001) of VAS score with a pooled MD of (-2.62) (95% CI: -2.83, -2.41; I2= 99%, P <0.00001); Knee society clinical rating system score (KSS) evaluation also showed significant elevation (P< 0.00001) with mean polled (29.59) (95% CI: 27.66, 31.52; I2= 95%, P< 0.0001); and significantly reduction (P<0.00001) of WOMAC score occurred as pooled MD of (-12.38) (95% CI: -13.75, -11.01; I2= 99%, P< 0.0001).ConclusionsArthroscopic guided high-dose subchondral application of primary cultured synovial mesenchymal stem cells in popliteal platelet-rich plasma media combined with hyaluronic acid effectively regenerate cartilage defect and increase clinical outcomes in the early stage of osteoarthritis.Level of EvidenceTherapeutic Level I.
Sitatunga (Tragelaphus spekii) food sources and habitat use in Marsh–Savannah‐cultivation mosaics
Authors: Murwanyi Peter Happy , Kityo Robert , Ssekuubwa Enock , Tweheyo Mnason 
Published: December 2023

AbstractWetland conversion threatens wetland specialists by reducing their core habitat. The sitatunga is a wetland specialist with declining populations. However, knowledge of sitatunga ecology and threats is limited, particularly outside protected areas. We examined sitatunga food sources, and habitat use in undisturbed Marshes and Marsh–Savannah transition blocks, and a Cultivated (disturbed) block in River Mayanja wetland, central Uganda. We recorded indirect indices and sightings of sitatunga along a 10 km transect in each block, and surveyed food sources in 34 plots along the transects. Our results indicate that the indices and sightings of Sitatunga had lower relative frequency in the Cultivated than in the Marshes and Marsh–Savannah transition blocks. Sitatunga feed on 39 plant species in 13 families and six growth forms; grasses, herbs, sedges, climbers, shrubs and water weeds. Cyperus papyrus, Echinochloa pyramidalis, Leersia hexandra accounted for 58% of sitatunga food sources. There were more individuals and species with Sitatunga feeding activity in the Marshes and Marsh–Savannah transition blocks than in the Cultivated block. Our results show that sitatunga habitat use and food sources are constrained in disturbed habitats while threats are intensified. To maintain wetland integrity and stability of sitatunga populations, stakeholders need to address wetland encroachment.
Oat β‐glucan repairs the epidermal barrier by upregulating the levels of epidermal differentiation, cell–cell junctions and lipids via Dectin‐1
Authors: Jing Rongrong , Fu Mengli , Huang Yuhan , Zhang Kaini , Ye Jiabin , Gong Fanghua , Jihea Ali Naji Nasser Al‐bashari , Xu Xiashun , Xiao Jiali , Yu Guangdong , Lin Shisheng , Zhao Wengang , Xu Nuo , Li Xiaokun , Li Zhiming , Gao Shuang 
Published: December 2023

AbstractBackground and PurposeOat β‐glucan could ameliorate epidermal hyperplasia and accelerate epidermal barrier repair. Dectin‐1 is one of the receptors of β‐glucan and many biological functions of β‐glucan are mediated by Dectin‐1. Dectin‐1 promotes wound healing through regulating the proliferation and migration of skin cells. Thus, this study aimed to investigate the role of oat β‐glucan and Dectin‐1 in epidermal barrier repair.Experimental ApproachTo investigate the role of Dectin‐1 in the epidermal barrier, indicators associated with the recovery of a damaged epidermal barrier, including histopathological changes, keratinization, proliferation, apoptosis, differentiation, cell–cell junctions and lipid content were compared between WT and Dectin‐1−/− mice. Further, the effect of oat β‐glucan on the disruption of the epidermal barrier was also compared between WT and Dectin‐1−/− mice.Key ResultsDectin‐1 deficiency resulted in delayed recovery and marked keratinization, as well as abnormal levels of keratinocyte differentiation, cell–cell junctions and lipid synthesis during the restoration of the epidermal barrier. Oat β‐glucan significantly reduces epidermal hyperplasia, promotes epidermal differentiation, increases cell–cell junction expression, promotes lipid synthesis and ultimately accelerates the recovery of damaged epidermal barriers via Dectin‐1. Oat β‐glucan could promote CaS receptor expression and activate the PPAR‐γ signalling pathway via Dectin‐1.Conclusion and ImplicationsOat β‐glucan promote the recovery of damaged epidermal barriers through promoting epidermal differentiation, increasing the expression of cell–cell junctions and lipid synthesis through Dectin‐1. Dectin‐1 deficiency delay the recovery of epidermal barriers, which indicated that Dectin‐1 may be a potential target in epidermal barrier repair.
Automated and intelligent system for World Health Organization data forecasting
Authors: Soares Felipe Augusto Lara , de Freitas Henrique Cota 
Published: December 2023

AbstractTechnological advances and social transformations have enabled the circulation of a large amount of data in the health area. Analyzing this data becomes more critical and more challenging as the volume of data increases. An alternative to performing this analysis is to use data analysis techniques to process input data sets and build consistent databases for input to machine learning algorithms. Thus, it can forecast future scenarios and collaborate with knowledge discovery. In this context, this work aims to develop a parameterizable system with automated decisions capable of collecting and analyzing many indicators provided by the World Health Organization (WHO). After these analysis steps, the system applies machine learning algorithms for predictions of different indicators to process information automatically, finding different knowledge discovery scenarios. Thus, the contribution of this article is an automated and intelligent system for WHO data forecasting. The efficiency of the system's choices and forecasts was proven with experiments in five different areas of health, obtaining assertiveness by up to 99.92%, root‐mean‐square error (RMSE) by up to 0.0286, and Kling‐Gupta Efficiency (KGE) by up to 0.9988, hitting even the most complex cases, as shown in the confusion matrices. Finally, three case studies were carried out to expand the studies and present the potential of the system in different contexts: anemia in children, age‐standardized suicide rates in men, and number of road traffic deaths.
Bare‐Bones particle Swarm optimization‐based quantization for fast and energy efficient convolutional neural networks
Authors: Tmamna Jihene , Ayed Emna Ben , Fourati Rahma , Hussain Amir , Ayed Mounir Ben 
Published: December 2023

AbstractNeural network quantization is a critical method for reducing memory usage and computational complexity in deep learning models, making them more suitable for deployment on resource‐constrained devices. In this article, we propose a method called BBPSO‐Quantizer, which utilizes an enhanced Bare‐Bones Particle Swarm Optimization algorithm, to address the challenging problem of mixed precision quantization of convolutional neural networks (CNNs). Our proposed algorithm leverages a new population initialization, a robust screening process, and a local search strategy to improve the search performance and guide the population towards a feasible region. Additionally, Deb's constraint handling method is incorporated to ensure that the optimized solutions satisfy the functional constraints. The effectiveness of our BBPSO‐Quantizer is evaluated on various state‐of‐the‐art CNN architectures, including VGG, DenseNet, ResNet, and MobileNetV2, using CIFAR‐10, CIFAR‐100, and Tiny ImageNet datasets. Comparative results demonstrate that our method delivers an excellent tradeoff between accuracy and computational efficiency.
Phytoplankton thermal trait parameterization alters community structure and biogeochemical processes in a modeled ocean
Authors: Anderson Stephanie I. , Fronda Clara , Barton Andrew D. , Clayton Sophie , Rynearson Tatiana A. , Dutkiewicz Stephanie 
Published: December 2023

AbstractPhytoplankton exhibit diverse physiological responses to temperature which influence their fitness in the environment and consequently alter their community structure. Here, we explored the sensitivity of phytoplankton community structure to thermal response parameterization in a modelled marine phytoplankton community. Using published empirical data, we evaluated the maximum thermal growth rates (μmax) and temperature coefficients (Q10; the rate at which growth scales with temperature) of six key Phytoplankton Functional Types (PFTs): coccolithophores, cyanobacteria, diatoms, diazotrophs, dinoflagellates, and green algae. Following three well‐documented methods, PFTs were either assumed to have (1) the same μmax and the same Q10 (as in to Eppley, 1972), (2) a unique μmax but the same Q10 (similar to Kremer et al., 2017), or (3) a unique μmax and a unique Q10 (following Anderson et al., 2021). These trait values were then implemented within the Massachusetts Institute of Technology biogeochemistry and ecosystem model (called Darwin) for each PFT under a control and climate change scenario. Our results suggest that applying a μmax and Q10 universally across PFTs (as in Eppley, 1972) leads to unrealistic phytoplankton communities, which lack diatoms globally. Additionally, we find that accounting for differences in the Q10 between PFTs can significantly impact each PFT's competitive ability, especially at high latitudes, leading to altered modeled phytoplankton community structures in our control and climate change simulations. This then impacts estimates of biogeochemical processes, with, for example, estimates of export production varying by ~10% in the Southern Ocean depending on the parameterization. Our results indicate that the diversity of thermal response traits in phytoplankton not only shape community composition in the historical and future, warmer ocean, but that these traits have significant feedbacks on global biogeochemical cycles.
CAPITAL DEPRECIATION AND INDUSTRY COMPETITION: EVIDENCE AND THEORY
Authors: Dang Alicia H. , Samaniego Roberto M. 
Published: December 2023

AbstractWe argue that the rate of capital depreciation is a determinant of competition. We show that the rate of capital depreciation has a robust positive relationship with market power in U.S. data. Then, we develop a general equilibrium model of industry competition where industries vary in their rate of capital depreciation. In equilibrium, optimal savings decisions imply that rapid depreciation is related to higher costs of capital, so that industries with rapid depreciation display less competition than industries with slow depreciation. Depending on parameters, the calibrated model can account for much of the observed dispersion in markups across U.S. industries.
Impact of fiber surface gas treatments on interfacial bonding in SiC/BN/SiC minicomposites
Authors: Chanson Charlotte , Jouannigot Stéphane , Jacques Sylvain 
Published: December 2023

AbstractBN interphases with different microstructures and a structural gradient were prepared by chemical vapor deposition (CVD) within SiC/SiC minicomposites. The interfacial shear stress (ISS) measured by the fiber push‐out test and the debonding location in the fiber/matrix interface zone during mechanical loading depends on the BN interphase structure. The ISS is higher when the structural organization of the BN interphase is poor, in which case debonding occurs on the fiber side. The Hi‐Nicalon S fiber surfaces were gas‐treated to strengthen the bond with the interphase. BCl3‐based reactive CVD treatments have produced a thin boron carbide layer on the fiber surface, resulting in a 30% increase in ISS. However, the minicomposites are brittle in tensile tests due to fiber bridging by parasitic boron clusters. Short‐time CVD of SiC increases the fiber surface roughness and doubles the ISS, but again the minicomposites are brittle, indicating the need to better modulate the resulting roughness and adjust the interphase. Finally, ammonia treatments have nitrided the fiber surface and increased the ISS by 12%. While the increase in interfacial bonding measured at the microscopic scale was small, this nitriding treatment did not embrittle the minicomposites at the macroscopic scale.
Rheology of a sodium‐molybdenum borosilicate melt undergoing phase separation
Authors: Pereira Luiz , Schuller Sophie , Wadsworth Fabian B. , Vasseur Jérémie , Lancelotti Ricardo F. , Hess Kai‐Uwe , Gossé Stéphane , Dingwell Donald B. 
Published: December 2023

AbstractDuring glass production, phase separation can result in the formation of suspended liquid droplets, which can cause changes in the system rheology. In nuclear waste vitrification context, some new glassy matrices may present this phase separation matter, but the mechanisms controlling the viscosity changes have not yet been determined. Here, we measure the viscosity of a sodium‐borosilicate melt containing dissolved MoO3 at different temperatures and subject to different applied shear strain rates. We observe that (i) the viscosity increases sharply as the temperature decreases and (ii) at any constant temperature below 1000°C, the system presents non‐Newtonian response. Using transmission electron microscope observations coupled with viscosity calculations, we interpret the cause of the observed changes as the result of phase separation. We show that the viscosity increase on cooling is in excess of the predicted temperature dependence for a homogeneous melt of the starting composition. The increase is due to the formation of a second phase and is controlled by chemical and structural modifications of the matrix during the loss of the elements that form the droplets. This work provides insights into the rheology of a system composed of two composition sets due to a miscibility gap.
Home visit scheduling for family interventions: a child protection case study
Authors: de Aguiar Ana Raquel Pena , Grassi Inês Clode de Freitas , Gomes Maria Isabel , Ramos Tânia Rodrigues Pereira 
Published: December 2023

AbstractFamily dynamics affect the development of children and youth, which can even endanger young people and lead to the loss of parental rights and subsequent institutionalization. Recent emphasis has been placed on working with families when a potentially risky situation is identified, aiming at developing skills within family members and avoiding institutionalization. Some organizations help to develop the social skills necessary for families to change negative dynamics. The organizations are not for profit and often lack the knowledge to plan their activities efficiently, particularly in allocating human resources to design, implement, and schedule home visit interventions. This work is motivated by one such organization that works with families needing support by regularly making home visits to monitor interventions. Currently, visits are scheduled manually with the technicians trying to coordinate schedules with each other and with the families. The increasing number of families referenced to the organization has made it difficult to keep track of the time intervals between visits, especially since visits are frequently cancelled (e.g., changing availability, attending court hearings). This work proposes an optimization model to help technicians plan home visits. It accounts for the time availability of technicians and families while ensuring a service level based on the time between visits. In addition, the new Mixed Integer Programing model, which is based on the assignment problem, also takes into account technicians’ work–life balance, worktime exemption, and technicians’ visiting time preferences. The results show the model schedules more than 260% of home visits while increasing the capacity used by 25 percentage points, demonstrating its usefulness.
Optimal pricing and warranty strategies of a closed‐loop supply chain under government subsidies
Authors: Li Jinhong , He Shuguang , Zhang Min 
Published: December 2023

AbstractBoth warranty services and subsidy policies are effective strategies for promoting the development of remanufacturing. According to the warranty provider, this paper considers two possible warranty strategies: the manufacturer warranty and the retailer warranty. The optimal pricing and warranty periods are determined by considering the effect of the consumption subsidy policy through Stackelberg game models. Subsequently, this paper investigates the optimal warranty strategy by comparing the economic and integrated performance of the closed‐loop supply chain. The analytical results indicate that the retailer warranty enables the supply chain to obtain a higher economic performance than the manufacturer warranty. Nevertheless, the integrated performance that combines economic and environmental performance depends on the consumption subsidy level. In addition, this paper finds that the consumption subsidy policy enhances supply chain profitability and consumer surplus but may hurt the environment in certain scenarios. Therefore, this paper derives the optimal subsidy level by maximizing the total social welfare, which takes into account both economic and environmental performance. These findings provide valuable insights for policymakers in remanufacturing.
Unveiling the potential: Enhancing caregiver knowledge through video education to address topical corticosteroid concerns in children with eczematous dermatitis
Authors: Sitthisan Manassaya , Wananukul Siriwan , Chatproedprai Susheera , Tempark Therdpong , Chantawarangul Karaked 
Published: December 2023

AbstractBackgroundConcerns about the use of topical corticosteroids (TCS) in pediatric eczematous dermatitis management often hinder effective treatment. Limited data exist regarding the prevalence of these concerns and the effectiveness of interventions. This study aimed to assess the prevalence of TCS concerns among caregivers and determine the effectiveness of video education in mitigating these concerns.MethodsA single‐center prospective study was conducted from 2022 to 2023, involving caregivers of children under 18 years with eczematous dermatitis. Baseline and post‐intervention questionnaires were administered after a 4‐week period. Caregivers received video education on TCS use, and the TOPICOP score was evaluated before and after viewing the video.ResultsThe study included 150 caregivers, 85.3% female and 74% had a child with atopic dermatitis. The prevalence of TCS concerns among Thai caregivers was 62%. Following video education, the prevalence of TCS concerns significantly decreased to 10.7%. Mean belief score decreased from 43.81 ± 13.45 to 31.85 ± 16.56, mean worry score decreased from 56.22 ± 18.27 to 40.41 ± 18.55 and mean total TOPICOP score decreased from 50.02 ± 12.65 to 36.13 ± 13.52 (p‐value <.001). The intervention also resulted in reduced disease exacerbations, duration of the rash, and duration of TCS use. The optimal TOPICOP cut‐off score to predict TCS concerns was identified as 43.06.ConclusionVideo education effectively alleviated TCS concerns among caregivers, addressing beliefs, worries, disease exacerbations, and side effects. Integration of this intervention into the management of pediatric eczematous dermatitis can yield optimal outcomes.
A developmental logic: Habermas's theory of social evolution
Authors: Oh Keunchang 
Published: December 2023

AbstractIn the paper, I first consider how his theory of social norms is connected to his theory of social evolution by examining the importance of learning in his theory of both social norms and social evolution. Then I turn to David Owen and Amy Allen's critiques of Jürgen Habermas. My aim is to develop their critique of Habermas by elucidating an important but neglected distinction between the developmental logic and the developmental dynamics in Habermas's theory of social evolution. Drawing on this distinction, I claim that Habermas's theory is problematic in that he underestimates the importance of the developmental dynamics. By introducing the distinction between individual learning and social learning, I also question his account of progress as accumulative experience of learning. This is because, unlike cumulative culture at the level of phylogenesis, individuals ontogenetically experience a kind of non‐cumulative social learning. Unlike cumulative culture, each individual has to undergo a kind of non‐cumulative social learning. The problem is that Habermas conceives the learning process too narrowly such that learning does not guarantee social evolution.
Theoretical Study on Falling Film Fin-Tube Dehumidifier Integrated With an Evaporative Cooler
Authors: Kalpana  , Subudhi Sudhakar 
Published: December 2023

Abstract
The current work presents the theoretical analysis of a falling film fin-tube dehumidifier integrated with an evaporative cooler using CaCl2 as a liquid desiccant. In a fin-tube dehumidifier, the fins are provided outside the tubes to sustain the solution temperature during dehumidification. The evaporative cooler is compiled with a dehumidifier to provide cool air over the fins for maintaining the solution and air temperature. The theoretical model examines the heat and mass transfer between the air and the solution, which are moving in a counterflow direction inside the tubes. The study first presents the validation of the theoretical model with the experimental findings. The maximum disparity between theoretical and experimental results for moisture reduction with solution volume flowrate is found to be ±6.2%, whereas it is discovered to be ±13.8% for moisture reduction with airflow rate. The paper then discusses the air and solution parameters variation along the tube height and the impact of air and solution inlet parameters on system performance. The findings indicate that the variation in outlet air humidity ratio with tube height from 0 to 1 m is observed highest, 0.0264 kg/kg d. a. to 0.0233 kg/kg d. a., for a solution volume flowrate of 12.5 LPM and an airflow rate of 0.05 kg/s. The maximum variation in moisture effectiveness with tube height is observed from 0.0045 to 0.292 at 5 LPM solution volume flowrate and 0.05 kg/s airflow rate.