bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANMCO (Italian Association of Hospital Cardiologists) scientific statement: obesity in adults—an approach for cardiologists
Authors: Di Fusco Stefania Angela , Mocini Edoardo , Gulizia Michele Massimo , Gabrielli Domenico , Grimaldi Massimo , Oliva Fabrizio , Colivicchi Furio 
Published: January 2024

AbstractObesity is a complex, chronic disease requiring a multidisciplinary approach to its management. In clinical practice, body mass index and waist-related measurements can be used for obesity screening. The estimated prevalence of obesity among adults worldwide is 12%. With the expected further increase in overall obesity prevalence, clinicians will increasingly be managing patients with obesity. Energy balance is regulated by a complex neurohumoral system that involves the central nervous system and circulating mediators, among which leptin is the most studied. The functioning of these systems is influenced by both genetic and environmental factors. Obesity generally occurs when a genetically predisposed individual lives in an obesogenic environment for a long period. Cardiologists are deeply involved in evaluating patients with obesity. Cardiovascular risk profile is one of the most important items to be quantified to understand the health risk due to obesity and the clinical benefit that a single patient can obtain with weight loss. At the individual level, appropriate patient involvement, the detection of potential obesity causes, and a multidisciplinary approach are tools that can improve clinical outcomes. In the near future, we will probably have new pharmacological tools at our disposal that will facilitate achieving and maintaining weight loss. However, pharmacological treatment alone cannot cure such a complex disease. The aim of this paper is to summarize some key points of this field, such as obesity definition and measurement tools, its epidemiology, the main mechanisms underlying energy homeostasis, health consequences of obesity with a focus on cardiovascular diseases and the obesity paradox.Level of evidence V: report of expert committees.
Relationship between dietary fiber and all-cause mortality, cardiovascular mortality, and cardiovascular disease in patients with chronic kidney disease: a systematic review and meta-analysis
Authors: Gai Wei , Lin Lihua , Wang Yuxuan , Bian Jia , Tao Yanling 
Published: January 2024

Abstract
Background
The potential protective effects of dietary fiber against all-cause mortality, cardiovascular mortality, and cardiovascular disease in patients with chronic kidney disease have not been definitively established. To verify this relationship, a systematic review and a meta-analysis were undertaken.

Methods
PubMed, The Cochrane Library, Web of Science, Embase, ProQuest, and CINAHL were used to systematically search for prospective cohort studies that investigate the association between dietary fiber and all-cause mortality, cardiovascular mortality, and cardiovascular disease in individuals with chronic kidney disease (CKD). This search was conducted up to and including March 2023.

Results
The analysis included 10 cohort studies, with a total of 19,843 patients who were followed up for 1.5–10.1 y. The results indicated a significant negative correlation between dietary fiber and all-cause mortality among patients with CKD (HR 0.80, 95% CI 0.58–0.97, P < 0.001). Subgroup analysis further revealed that the study population and exposure factors were significantly associated with all-cause mortality (P < 0.001). Increased dietary fiber intake was associated with a reduced risk of cardiovascular mortality (HR 0.78; 95% CI 0.67–0.90) and a reduced incidence of cardiovascular disease (HR 0.87; 95% CI 0.80–0.95) among patients with CKD.

Conclusions
The pooled results of our meta-analysis indicated an inverse association between dietary fiber intake and all-cause mortality, cardiovascular mortality, and cardiovascular disease.

Graphical abstract
Current trends in antimicrobial activities of carbon nanostructures: potentiality and status of nanobiochar in comparison to carbon dots
Authors: Nishshankage Kulathi , Fernandez Andrea Breverly , Pallewatta Shiran , Buddhinie P. K. C. , Vithanage Meththika 
Published: January 2024

AbstractThe increase in antimicrobial resistance (AMR) poses a massive threat to world health, necessitating the urgent development of alternative antimicrobial growth control techniques. Due to their specific physical and chemical properties, nanomaterials, particularly carbon-based nanomaterials, have emerged as attractive candidates for antimicrobial applications, however, reviews are lacking. This comprehensive review aims to bridge the existing knowledge gaps surrounding the mechanism and significance of nanobiochar (NBC) and carbon nanostructures in the field of antimicrobial applications. Notably, NBC, which is derived from biochar, exhibits promising potential as an environmentally-friendly substance with antimicrobial properties. Its strong adsorption capabilities enable the removal and immobilization of pathogens and pollutants from soil and water and also exhibit antimicrobial properties to combat harmful pathogens. In addition to NBC, carbon dots (CDs) and graphene oxide (GO) have also shown excellent antimicrobial properties. These carbon-based nanomaterials find applications in agriculture for phytopathogen control and post-harvest disease management, as well as in medicine for nanotheranostics and in the food industry for extending shelf life as an eco-friendly alternative to chemicals and antibiotics. However, the long-term toxicity of these nanoparticles to humans and the environment needs further investigation, considering the influence of different physiochemical characteristics on antimicrobial properties and nanotoxicity. Therefore, continued exploration in this area will pave the way for future research and safe deployment strategies of carbon-based nanomaterials in combating microbial threats.
Graphical Abstract
Evaluating indwelling devices and other risk factors for mortality in invasive Carbapenem-resistant Enterobacterales infections in Georgia, 2012–2019
Authors: Witt Lucy S. , Sexton Mary Elizabeth , Smith Gillian , Farley Monica , Jacob Jesse T. 
Published: January 2024

Abstract

Objective:
Carbapenem-resistant Enterobacterales (CRE) infections are a public health threat due to the risk of transmission between patients and high associated mortality. We sought to identify risk factors for mortality in patients with invasive CRE infections and to specifically evaluate whether there was an association between indwelling medical devices and 90-day mortality.

Design:
Retrospective observational cohort study of patients infected with CRE in the eight-county metropolitan Atlanta area between 2012 and 2019.

Methods:
Patients with invasive CRE infections were identified via the Georgia Emerging Infections Program’s active, population- and laboratory-based surveillance system and linked with the Georgia Vital Statistics database. We used bivariate analysis to identify risk factors for mortality and completed log binomial multivariable regression to estimate risk ratios (RR) for the association between indwelling devices and mortality.

Results:
In total, 154 invasive CRE infections were identified, with indwelling devices present in most patients (87.7%) around the time of infection. Admission to an intensive care unit was found to be associated with 90-day mortality (adjusted RR [aRR] 1.55, 95% CI 1.07, 2.24); however, the presence of any indwelling device was not associated with increased risk of 90-day mortality in multivariable analysis (aRR 1.22, 95% CI 0.55, 2.73). Having at least two indwelling devices was associated with increased mortality (aRR 1.79, 95% CI 1.05, 3.05).

Conclusions:
Indwelling devices were prevalent in our cohort but were not consistently associated with an increased risk of mortality. Further studies are needed to examine this relationship and the role of device removal.
Protecting Future People’s Future: How to Operationalise Present People’s Unfulfilled Promises to Future Generations
Authors: Alemanno Alberto 
Published: January 2024

AbstractAs societies become more concerned with their impacts on future generations, the question of how to translate that concern into greater consideration in contemporary decision-making is coming to the fore. Despite growing societal acceptance of the ethics of obligations to the future – as reflected in record-high number of future-sensitive constitutions and international treaties – present generations’ promises to future generations remain unfulfilled. This article explains why and offers an alternative approach to future-proofing. After providing a systematic account of the multiple efforts at aligning the actions of decision-makers with the interests of future generations, it argues that achieving the inclusion of future generations’ interests in contemporary policymaking requires more than their legal codification and the establishment of new and typically scattered institutions, mechanisms and procedures. It rather calls for a more holistic, future-orientated and proactive approach by all public authorities. These must increasingly be expected to create the conditions not only for policymakers to consider the temporal dimension of their decisions, but also for all stakeholders – including new dedicated institutions – to hold present people accountable to currently non-existent future generations. To do so beyond the environment and climate space is a matter of urgency. This is the spirit animating this Special Issue devoted to long-term risks and future generations: to nurture a more imaginative theorisation and operationalisation of the recognition of future generations’ interests in contemporary policymaking beyond today’s institutional and conceptual models.
IDENTITY THROUGH DIFFERENCE IN BEAT FURRER'S LOTÓFAGOS
Authors: Cooper Ed 
Published: January 2024

AbstractIn Homer's The Odyssey, Odysseus and his men are on their way home to Ithaca when they land on a remote island inhabited by lotus-eaters. The locals share their indolent-making lotus plants with the Greeks, such that the troops’ homeward journey is disrupted and they find themselves in a state of limbo. Identities, both individual and communal, become entangled and blurred. Beat Furrer takes these sorts of uncertainties of self as inspiration in his Lotófagos (2007) – that is, Lotus-eaters – scored for soprano and double bass, which sets José Ángel Valente's poem of the same name. Drawing on Gilles Deleuze's conception of bodies, this article argues that the identity of an elusive but persistent collective subject in Valente's text can be found within the difference between the two performers’ bodies in Furrer's setting. The pair's movements weave in and out of each other, moving through spectres of each other's material, fleetingly suggesting cohesion through tension before jettisoning this for what contextually appears as relief. As such, the series of surreptitious vignettes presents a ‘conatus’ of the piece defined by tension, emulation and transience; Furrer's Lotófagos creates space for Valente's mysterious subject to be presented as the immanence of forces between two performing bodies.
A user model to directly compare two unmodified interfaces: a study of including errors and error corrections in a cognitive user model
Authors: Tehranchi Farnaz , Bagherzadeh Amirreza , Ritter Frank E. 
Published: January 2024

Abstract
User models that can directly use and learn how to do tasks with unmodified interfaces would be helpful in system design to compare task knowledge and times between interfaces. Including user errors can be helpful because users will always make mistakes and generate errors. We compare three user models: an existing validated model that simulates users’ behavior in the Dismal spreadsheet in Emacs, a newly developed model that interacts with an Excel spreadsheet, and a new model that generates and fixes user errors. These models are implemented using a set of simulated eyes and hands extensions. All the models completed a 14-step task without modifying the system that participants used. These models predict that the task in Excel is approximately 20% faster than in Dismal, including suggesting why, where, and how much Excel is a better design. The Excel model predictions were compared to newly collected human data (N = 23). The model’s predictions of subtask times correlate well with the human data (r2 = .71). We also present a preliminary model of human error and correction based on user keypress errors, including 25 slips. The predictions to data comparison suggest that this interactive model that includes errors moves us closer to having a complete user model that can directly test interface design by predicting human behavior and performing the task on the same interface as users. The errors from the model’s hands also allow further exploration of error detection, error correction, and different knowledge types in user models.
“In-patient echocardiography utilization post repair of congenital heart disease. Analysis of data from the Pediatric Health Information System from 2010 to 2019”
Authors: Skaff Adam M. , Valikodath Nishma G. , Godown Justin , Parra David A. 
Published: January 2024

AbstractBackground:Echocardiography is a key diagnostic tool for medical decision-making following congenital heart surgery. Overall utilisation of echocardiography for specific congenital heart lesions following cardiac surgery has not previously been reported. This study aims to assess echocardiogram utilisation following the surgical repair of CHD to describe the variation in use across centres and provide clinical benchmarks.Methods:All patients < 18 years of age undergoing surgical repair of CHD were identified from the Pediatric Health Information System from 2010 to 2019. Surgeries were grouped based on their Risk Adjustment for Congenital Heart Surgery-1 scores. Detailed billing data were used to assess the frequency/cost of post-operative echocardiograms, phase of hospital care, and hospital length of stay.Results:In total, 37,238 surgical encounters were identified for inclusion across 48 centres. Higher Risk Adjustment for Congenital Heart Surgery scores were associated with an increased median number of post-operative echocardiograms (2 versus 4 in Risk Adjustment for Congenital Heart Surgery score 1 versus 6, p < 0.001), and longer median post-operative length of stay (3 days versus 31 days in Risk Adjustment for Congenital Heart Surgery score 1 versus 6, p < 0.001). After accounting for surgical complexity, there was significant variability in echocardiogram utilisation across centres (median daily echocardiogram utilisation range 0.2/day–0.6/day, p < 0.001). There is no difference in the proportion of patients with high surgical complexity (Risk Adjustment for Congenital Heart Surgery ≥ 4) between centres with high versus low echocardiogram utilisation (p = 0.44).Conclusions:Increasing surgical complexity is associated with longer post-operative length of stay and increased utilisation of echocardiography. There is wide variability in echocardiography resource utilisation across centres, even when accounting for surgical complexity.
Research Gaps and Priorities for Terrestrial Water and Earth System Connections From Catchment to Global Scale
Authors: Zarei Mohanna , Destouni Georgia 
Published: January 2024

AbstractThe out‐of‐sight groundwater and visible but much less extensive surface waters on land constitute a linked terrestrial water system around the planet. Research is crucial for our understanding of these terrestrial water system links and interactions with other geosystems and key challenges of Earth System change. This study uses a scoping review approach to discuss and identify topical, methodological and geographical gaps and priorities for research on these links and interactions of the coupled ground‐ and surface water (GSW) system at scales of whole‐catchments or greater. Results show that the large‐scale GSW system is considered in just a small part (0.4%–0.8%) of all studies (order of 105 for each topic) of either groundwater or surface water flow, storage, or quality at any scale. While relatively many of the large‐scale GSW studies consider links with the atmosphere or climate (8%–43%), considerably fewer address links with: (a) the cryosphere or coastal ocean as additional interacting geosystems (5%–9%); (b) change drivers/pressures of land‐use, water use, or the energy or food nexus (2%–12%); (c) change impacts related to health, biodiversity or ecosystem services (1%–4%). Methodologically, use of remote sensing data and participatory methods is small, while South America and Africa emerge as the least studied geographic regions. The paper discusses why these topical, methodological and geographical findings indicate important research gaps and priorities for the large‐scale coupled terrestrial GSW system and its roles in the future of the Earth System.
Kinematic Afterslip Patterns
Authors: Meade Brendan J. 
Published: January 2024

AbstractNon‐inertial afterslip has been inferred to occur following large earthquakes. An explanation for this slow slip phenomenon is that coseismically generated stresses induce sliding on parts of a fault surface with velocity‐strengthening frictional properties. Here we develop an alternative mesoscale heuristic explanation for afterslip based on the idea that afterslip may occur on any portion of a fault that exhibits positive residual geometric moment following an earthquake, including sections that ruptured coseismically. Following a large earthquake, this model exhibits exponential time decay of afterslip and allows for variable sensitivity to coseismic event magnitude and residual geometric moment. This model provides a partial explanation for the spatial relationship of co‐ and post‐seismic slip associated with the 2011 MW = 9 Tohoku‐oki earthquake.
IMF By Effects on the Strength and Latitude of Polar Electrojets: CHAMP and Swarm Joint Observations
Authors: Wang Hui , Lühr Hermann 
Published: January 2024

AbstractIn this study, the impact of the interplanetary magnetic field (IMF) By component on the peak strength and position of polar electrojets (PEJs) is analyzed, based on 16 years of joint observations from Challenging Minisatellite Payload (CHAMP; 2000–2010) and Swarm (2014–2020) satellites, while focusing on the local time and hemispherical differences. With a more positive IMF By, the duskside eastward PEJ enhances significantly at June solstice in the Northern Hemisphere. Around midnight, the impact of IMF By on the PEJ is more significant in the winter hemisphere; the westward PEJ is stronger in the Northern (Southern) Hemisphere for a more positive (negative) IMF By. In 03–08 MLT, the impact of IMF By is similar in both the winter and summer hemispheres: for IMF By > 0 and By < 0, the PEJ in the dawn sector is stronger in the December and June solstices, respectively. Around noon, a more duskward (dawnward) IMF By component leads to a higher eastward (westward) PEJ in the northern (southern) summer hemisphere. The northern westward (eastward) PEJ peaks at higher latitudes than the southern PEJ for a negative (positive) IMF By.
The Development of Atmospheric Bores in Non‐Uniform Baroclinic Environments and Their Roles in the Maintenance, Structure, and Evolution of an MCS
Authors: Zhang Shushi , Parsons David B. , Xu Xin , Huang Hong , Xu Fen , Wu Tianjie , Chen Gang , Abulikemu Abuduwaili , Zhao Yating , Zhang Shengxi , Tang Ying 
Published: January 2024

AbstractThis study used radar observations and a high‐resolution numerical simulation to explore the interactions between an mesoscale convective system (MCS), cold pool outflows, and atmospheric bores in a non‐uniform baroclinic environment. The bores were generated by a nocturnal MCS that occurred on 2–3 June 2017 over the southern North China Plain. The goal of this investigation is to determine how the structure of bores varied within this non‐uniform environment and whether and how the bores would maintain the MCS and alter its structure. To the southwest of the MCS, where there was large CAPE and a well‐mixed boundary layer, discrete convection initiation occurred behind a single radar fine line (RFL) maintaining the propagation of the MCS. To the southeast of the MCS, multiple RFLs were found suggesting the generation of an undular bore in an environment containing an intense nocturnal stable boundary layer with dry upper layers and little CAPE. Hydraulic and nonlinear theory were applied to the simulation of the MCS revealing that the differences in the bore evolution depended on both the characteristics of the cold pool and the variations in the ambient environment. Thus, the characteristics of the ambient environment and the associated differences in bore structure impacted the maintenance and organization of the MCS. This study implies the importance of an accurate representation of the low‐level ambient environment and the microphysics and kinematics within the MCS to accurately simulate and forecast cold pools, the generation and evolution of bores, and their impact on nocturnal MCSs.
Changes in Water Age During Dry‐Down of a Non‐Perennial Stream
Authors: Swenson Logan J. , Zipper Sam , Peterson Delaney M. , Jones C. Nathan , Burgin Amy J. , Seybold Erin , Kirk Matthew F. , Hatley Camden 
Published: January 2024

AbstractNon‐perennial streams, which lack year‐round flow, are widespread globally. Identifying the sources of water that sustain flow in non‐perennial streams is necessary to understand their potential impacts on downstream water resources, and guide water policy and management. Here, we used water isotopes (δ18O and δ2H) and two different modeling approaches to investigate the spatiotemporal dynamics of young water fractions (Fyw) in a non‐perennial stream network at Konza Prairie (KS, USA) during the 2021 summer dry‐down season, as well as over several years with varying hydrometeorological conditions. Using a Bayesian model, we found a substantial amount of young water (Fyw: 39.1–62.6%) sustained flows in the headwaters and at the catchment outlet during the 2021 water year, while 2015–2022 young water contributions estimated using sinusoidal models indicated smaller Fyw amounts (15.3% ± 5.7). Both modeling approaches indicate young water releases are highly sensitive to hydrological conditions, with stream water shifting to older sources as the network dries. The shift in water age suggests a shift away from rapid fracture flow toward slower matrix flow that creates a sustained but localized surface water presence during late summer and is reflected in the annual dynamics of water age at the catchment outlet. The substantial proportion of young water highlights the vulnerability of non‐perennial streams to short‐term hydroclimatic change, while the late summer shift to older water reveals a sensitivity to longer‐term changes in groundwater dynamics. Combined, this suggests that local changes may propagate through non‐perennial stream networks to influence downstream water availability and quality.