bluuebunny/crossref_metadata_2025_split huggingface dataset:
myAURA: a personalized health library for epilepsy management via knowledge graph sparsification and visualization
Authors: Correia Rion Brattig , Rozum Jordan C , Cross Leonard , Felag Jack , Gallant Michael , Guo Ziqi , Herr Bruce W , Min Aehong , Sanchez-Valle Jon , Stungis Rocha Deborah , Valencia Alfonso , Wang Xuan , Börner Katy , Miller Wendy , Rocha Luis M 
Published: February 2025

Abstract

Objectives
Report the development of the patient-centered myAURA application and suite of methods designed to aid epilepsy patients, caregivers, and clinicians in making decisions about self-management and care.

Materials and Methods
myAURA rests on an unprecedented collection of epilepsy-relevant heterogeneous data resources, such as biomedical databases, social media, and electronic health records (EHRs). We use a patient-centered biomedical dictionary to link the collected data in a multilayer knowledge graph (KG) computed with a generalizable, open-source methodology.

Results
Our approach is based on a novel network sparsification method that uses the metric backbone of weighted graphs to discover important edges for inference, recommendation, and visualization. We demonstrate by studying drug-drug interaction from EHRs, extracting epilepsy-focused digital cohorts from social media, and generating a multilayer KG visualization. We also present our patient-centered design and pilot-testing of myAURA, including its user interface.

Discussion
The ability to search and explore myAURA’s heterogeneous data sources in a single, sparsified, multilayer KG is highly useful for a range of epilepsy studies and stakeholder support.

Conclusion
Our stakeholder-driven, scalable approach to integrating traditional and nontraditional data sources enables both clinical discovery and data-powered patient self-management in epilepsy and can be generalized to other chronic conditions.
Unplanned Extubation in the Burn Unit: A Retrospective Review
Authors: Nelson Cameron , Weigel Isaac , Galet Colette , Wibbenmeyer Lucy , Kurjatko Alexander 
Published: February 2025

Abstract
Unplanned extubation rates in burn patients were previously reported at 27% (3 cases per 100 ventilator days). As facial burns pose a unique challenge to tube securement, patients in our unit have surgically placed bite blocks to secure the endotracheal tube at the provider’s discretion. Herein, we assessed unplanned extubation rates at our burn center. We performed a retrospective cohort study including burn patients who required mechanical ventilation from 7/01/2015 to 6/30/2023. Demographics, comorbidities, injuries, and hospital course information were collected and compared between patients who had an unplanned extubation and those who did not. Binary logistic regression analyses were performed to identify factors associated with unplanned extubation and ventilator-associated pneumonia (VAP) complication. P &lt; 0.05 was considered significant. Of 360 patients, 17 (4.7%) had unplanned extubations, representing 0.7 cases per 100 ventilator days. There were no significant differences in demographics, comorbidities, or burn injury characteristics between groups. Patients with unplanned extubation were more likely to have an inhalation injury (70.6% vs. 42.6%, p=0.001), paCO2 ≥50 (70.6% vs. 39.1%, p=0.031), more ventilator days (6 [2-15] vs. 2 [1-4] days, p&lt;0.001), and more hospital days (14 [8.5-25.5] vs. 8 [2-20], p=0.020). VAP rate tended to be higher in the unplanned extubation group (17.6% vs. 5.5%, p=0.077. On multivariate analysis, inhalation injury was associated with increased risk of unplanned extubation (Odds ratio (OR) = 4.68 [1.59-13.81], p=0.005). No patients with bite blocks had an unplanned extubation. Further study on the utility of advanced securement devices is recommended.
Method for estimating physical interaction forces using human–exoskeleton kinematic modelling and energy optimization
Authors: Lim Seungbum , Kim Woojin , Suh Jungwook 
Published: February 2025

Abstract
Exoskeleton robots mimic the structure of the human body and are physically connected to the wearer through attachment parts such as cuffs or straps. Nevertheless, misalignment between the human body and the robot can occur due to improper wearing of the exoskeleton, the elasticity of human skin, and the geometric complexity of human joint movements. Such misalignment increases unnecessary physical interaction forces, causing discomfort and pain to the wearer. Therefore, these interaction forces should be considered when designing exoskeleton robots to ensure wearability. In this study, we propose a method for estimating human-exoskeleton interaction forces through posture prediction. The human-robot connection is modeled as an elastic element, and posture is predicted using an energy optimization algorithm. The predicted posture is then used to calculate the interaction forces. Since this method considers only the physical characteristics of the exoskeleton robot and wearer, it enables objective evaluation of the robot without the need to manufacture actual prototypes. We performed quantitative experiments using prototypes of a sensor-equipped dummy and an exoskeleton to confirm the effectiveness of the modeling method. Consequently, the proposed method is expected to reduce the time and costs associated with developing exoskeleton robots and obviate the need for human subject testing.
Efficient source-independent Q-compensated least-squares reverse time migration with LNCC imaging condition
Authors: Liu Wei , Shi Ying , Wang Ning , Li Songling 
Published: February 2025

Abstract
Source-independent Q-compensated least squares reverse time migration based on the convolutional misfit function constitutes an amplitude-preserving methodology that effectively compensates for seismic attenuation and alleviates the constraints imposed by the source wavelet. Nevertheless, its conventional implementation, which constructs the gradient through the cross-correlation between background wavefield and adjoint wavefield propagating in opposite directions, incurs exorbitant storage and computational expenses. To ease the computational and storage pressures, we develop an efficient source-independent Q-compensated scheme by introducing a local Nyquist cross-correlation imaging condition to formulate gradient. Instead of employing entire wavefields for migration, the local Nyquist cross-correlation imaging condition, in combination with the Nyquist rate, adopts only the local wavefields around the excitation amplitude time. Consequently, the proposed scheme considerably diminishes the storage requirement as well as the additional time resulting from frequent input-output (I/O) operations, thereby enhancing computational efficiency. Numerical examples conducted on the 2D layered model, Marmousi model, field data, and the 3D overthrust model reveal that the proposed scheme is capable of attaining imaging accuracy comparable to that of the conventional scheme, while exhibiting superior storage and computing performance, and possesses higher feasibility in 3D applications.
Virtue Monism and Medical Practice: Practical Wisdom as Cross-Situational Ethical Expertise
Authors: De Caro Mario , Bina Federico , Bonicalzi Sofia , Brunetti Riccardo , Croce Michel , Kerusauskaite Skaistė , Navarini Claudia , Ricci Elena , Vaccarezza Maria Silvia 
Published: February 2025

Abstract
This article defends the centrality of practical wisdom in medical practice by building on a monistic view of moral virtue, termed the “Aretai model,” according to which possession of practical wisdom is necessary and sufficient for virtuousness, grounding both moral growth and effective moral behavior. From this perspective, we argue that practical wisdom should be conceived as a cross-situational ethical expertise consisting of four skills:moral perception, moral deliberation, emotion regulation, and moral motivation. Conceiving of practical wisdom as both overall virtuousness and ethical expertise makes it possible to deal adequately with the uniqueness of concrete ethically relevant situations. We contend that this becomes particularly evident in the context of medical practice, both in terms of decision-making and action-taking, especially in the most challenging or contentious clinical cases. We conclude the article by suggesting the potential implications of the Aretai model for continuing education in medical and healthcare professions.
Adverse effects of nanoparticles on humans
Authors: Morimoto Yasuo , Izumi Hiroto , Tomonaga Taisuke , Nishida Chinatsu , Higashi Hidenori 
Published: February 2025

Abstract
It was previously thought that the particles inhaled by humans and having adverse effects were micron-sized; particles with a particularly high content of crystalline silica were thought to have harmful effects. In recent years, manufactured materials have been further refined to nano-level particles, and it has been reported that these ultrafine particles have different adverse effects, making it necessary to perform occupational health management for chemicals that differ from micron-sized particles. Here we report the adverse effects of carbon nanotubes, welding fumes, and organic substances as examples of nanoparticles.
“They Do Not Have Physiognomies of Their Own”: Tracking Racialization of Maritime Professions in the Eighteenth-Century Portuguese Empire
Authors: Crutcher Megan , Belton Lloyd 
Published: February 2025

Abstract
During the second half of the long eighteenth century, various nations and empires began keeping records of sailors arriving and departing certain ports. In Portugal, all sailors were required to register at the Junta do Comércio (the board of trade), a measure enacted in the wake of a ban on the importation of enslaved people into the kingdom in 1761; an exemption was later made for enslaved sailors or crew members. This article draws on a data set of 344 sailors registered in logs of the Junta’s Lisbon office, dating from 1767, when the board was formed, to 1788, when it was absorbed into the royal court. Our analysis shows how the Junta’s logbooks became a contested space in which enslaved and free sailors of color attempted to define their own occupations, racial identities, and legal status in terms that frequently conflicted with the increasingly homogenized racialization of the state. We link the patterns of increased racialization of sailor records in Portugal to wider Atlantic developments in Brazil, France, Britain, and elsewhere to show how, during a period of immense political, economic, and social change in the long eighteenth century, racial categories were created, expanded, and disseminated across empires. The racialized vocabulary and mechanisms of anti-Blackness were developed, tested, and implemented via maritime networks during an age of capitalist and imperialist growth.
Integrating cold hardiness and deacclimation resistance demonstrates a conserved response to chilling accumulation in grapevines
Authors: Londo Jason P , Kovaleski Al P 
Published: February 2025

Abstract
To survive the harsh conditions of winter, woody perennial species such as grapevine have adapted to use environmental cues to trigger physiological changes to induce dormancy, acquire cold hardiness, and measure the length of winter to properly time spring budbreak. Human induced climate change disrupts these cues by prolonging warm temperatures in fall, reducing the depth and consistency of midwinter, and triggering early budbreak through false spring events. We evaluated variation in dormant bud cold hardiness and chilling hour requirements of 31 different grapevine varieties over 3 years. Differential thermal analysis was used to track changes in cold hardiness and deacclimation resistance was assessed throughout the season to track dormancy progression. Results demonstrate wide variation in maximum deacclimation rate (1.03 – 2.87 °C/day) among varieties under forcing conditions. Significant correlations were noted between wild species distributions or cultivar provenance with cold hardiness and deacclimation rates, demonstrating the likely climate-adaptive nature of these traits. When integrated with variation in cold hardiness, these rates revealed a relationship between winter cold hardiness, changes in deacclimation rate and budbreak phenology. Standardizing rates among varieties as deacclimation potential demonstrated a conserved response to chilling exposure among varieties that alters our interpretation of the concept of high and low chill varieties and chilling requirement in grapevine.
Detection and antimicrobial resistance profiles of Salmonella enterica recovered from house fly intestinal tracts and environments of selected broiler farms in Texas
Authors: Zwally Kirsten M , Holda Elizabeth , Perez Isaac , Kaufman Phillip E , Lyons Brandon , Athrey Giridhar , Taylor T Matthew 
Published: February 2025

Abstract
The entry of drug-resistant Salmonella enterica into the food supply is a challenge to public health and food safety. One emerging concern is the role of synanthropic insects for moving microbial pathogens throughout poultry production systems, where insects commonly thrive. We investigated the presence and phenotypic antimicrobial susceptibility of S. enterica from insect and environmental samples from broiler farms. Insects were collected throughout the broiler house and adjacent compost barn. Environmental samples (poultry feed, drinking water, fresh litter, and feces) were collected simultaneously (n = 80). Insect gastrointestinal tracts were dissected and pooled (n = 57). Recovered Salmonella isolates were serotyped and subjected to antimicrobial susceptibility testing against 14 medically important antimicrobials. Overall, six isolates were recovered from 137 total samples (4.4%): 3.5% (2/57) from adult house flies (Musca domestica), 15% (3/20) from poultry feed, and 4.8% (1/21) from litter. Salmonella Montevideo (16.7%; 1/6), Typhimurium (33.3%; 2/6), and Kentucky (50%, 3/6) were identified. All but one Salmonella isolate (83.3%; 5/6) demonstrated resistance to at least one antimicrobial. Further research should investigate movement patterns between broiler operations and food processing facilities to establish efficient biosecurity measures to prevent any instances of foodborne pathogen transmission into human food systems.
Direct N-body simulations of NGC 6397 and its tidal tails
Authors: Arnold Anthony D , Baumgardt Holger 
Published: February 2025

ABSTRACT
We have performed a series of direct N-body simulations that study the evolution of the Galactic globular cluster NGC 6397 under the combined influence of two-body relaxation, stellar evolution, and the Milky Way’s tidal field. Our simulations follow the evolution of the cluster over the last several Gyr up to its present-day position in the Milky Way in order to allow us to derive present-day cluster parameters and the distribution of its extra-tidal stars. We have also determined a new density profile of NGC 6397 by selecting stars from Gaia Data Release 3 (DR3) using Gaia DR3 proper motions, parallaxes, and photometry to discriminate cluster members from non-members. This allows us to derive the surface density profile of NGC 6397 and the location of its tidal tails up to $10^{\circ }$ of the cluster centre, well beyond the tidal radius of NGC 6397. Our results show that the current state of NGC 6397 in terms of surface density, velocity dispersion profile, and stellar mass function can be matched by a cluster model evolving from a standard initial mass function and does not require an additional central cluster of dark remnants. We also find good agreement in the location and absolute number of the extra-tidal stars between our simulations and the observations, making it unlikely that NGC 6397 is surrounded by a dark matter halo.
The Dark Energy Survey Supernova Program: an updated measurement of the Hubble constant using the inverse distance ladder
Authors: Camilleri R , Davis T M , Hinton S R , Armstrong P , Brout D , Galbany L , Glazebrook K , Lee J , Lidman C , Möller A , Nichol R C , Sako M , Scolnic D , Shah P , Smith M , Sullivan M , Sánchez B O , Vincenzi M , Wiseman P , Allam S , Abbott T M C , Aguena M , Andrade-Oliveira F , Asorey J , Avila S , Bacon D , Bechtol K , Bocquet S , Brooks D , Buckley-Geer E , Burke D L , Rosell A Carnero , Carollo D , Carretero J , Castander F J , Conselice C , da Costa L N , Pereira M E S , Desai S , Diehl H T , Everett S , Ferrero I , Flaugher B , Frieman J , García-Bellido J , Gaztanaga E , Giannini G , Gruendl R A , Herner K , Hollowood D L , Honscheid K , Huterer D , James D J , Kent S , Kuehn K , Lahav O , Lee S , Lewis G F , Lima M , Marshall J L , Mena-Fernández J , Miquel R , Myles J , Ogando R L C , Palmese A , Pieres A , Plazas Malagón A A , Romer A K , Roodman A , Samuroff S , Sanchez E , Sanchez Cid D , Schubnell M , Sevilla-Noarbe I , Suchyta E , Suntzeff N , Swanson M E C , Tarle G , Tucker B E , Walker A R , Weaverdyck N ,   DES Collaboration
Published: February 2025

ABSTRACT
We measure the current expansion rate of the Universe, Hubble’s constant $H_0$, by calibrating the absolute magnitudes of supernovae to distances measured by baryon acoustic oscillations (BAO). This ‘inverse distance ladder’ technique provides an alternative to calibrating supernovae using nearby absolute distance measurements, replacing the calibration with a high-redshift anchor. We use the recent release of 1829 supernovae from the Dark Energy Survey spanning $0.01\lt z\lt 1.13$ anchored to the recent baryon acoustic oscillation measurements from Dark Energy Spectroscopic Instrument (DESI) spanning $0.30 \lt z_{\mathrm{eff}}\lt 2.33$. To trace cosmology to $z=0$, we use the third-, fourth-, and fifth-order cosmographic models, which, by design, are agnostic about the energy content and expansion history of the universe. With the inclusion of the higher redshift DESI-BAO data, the third-order model is a poor fit to both data sets, with the fourth-order model being preferred by the Akaike Information Criterion. Using the fourth-order cosmographic model, we find $H_0=67.19^{+0.66}_{-0.64}\mathrm{~km} \mathrm{~s}^{-1} \mathrm{~Mpc}^{-1}$, in agreement with the value found by Planck without the need to assume Flat-$\Lambda$CDM. However, the best-fitting expansion history differs from that of Planck, providing continued motivation to investigate these tensions.
Discs around young free-floating planetary-mass objects: ultradeep Spitzer imaging of IC348
Authors: Seo Holly Hanbee , Scholz Aleks 
Published: February 2025

ABSTRACT
Protoplanetary discs have been found around free-floating objects with masses comparable to those of giant planets. The frequency and properties of these discs around planetary-mass objects are still debated. Here, we present ultradeep mid-infrared images for the young cluster IC348, obtained through stacking of time-series images from Spitzer. We measure fluxes at 3.6 and 4.5 $\mu$m for known free-floating planetary-mass objects (FFPMOs, spectral type M9 or later) in this cluster. By comparing the observed infrared spectral energy distributions with photospheric templates, we identify six planetary-mass objects with discs, plus three, which may or may not have a disc. This corresponds to a disc fraction of $46\pm ^{13}_{12}$ per cent. The disc fraction among planetary-mass objects is comparable to more massive brown dwarfs. We show the disc fraction among FFPMOs as a function of age, demonstrating that these objects retain discs for several million years, similar to low-mass stars and brown dwarfs.
A comprehensive study of the gas-phase formation network of HC5N: theory, experiments, observations and models
Authors: Giani Lisa , Bianchi Eleonora , Fournier Martin , Ely Sidaty Cheikh Sid , Ceccarelli Cecilia , Rosi Marzio , Guillemin Jean-Claude , Sims Ian R , Balucani Nadia 
Published: February 2025

Abstract
Cyanopolyynes are among the largest and most commonly observed interstellar Complex Organic Molecules in star-forming regions. They are believed to form primarily in the gas-phase, but their formation routes are not well understood. We present a comprehensive study of the gas-phase formation network of cyanobutadiyne, HC5N, based on new theoretical calculations, kinetics experiments, astronomical observations, and astrochemical modeling. We performed new quantum mechanics calculations for six neutral-neutral reactions in order to derive reliable rate coefficients and product branching fractions. We also present new CRESU data on the rate coefficients of three of these reactions (C3N + C2H2, C2H + HC3N, CN + C4H2) obtained at temperatures as low as 24 K. In practice, six out of nine reactions currently used in astrochemical models have been updated in our reviewed network. We also report the tentative detection of the 13C isotopologues of HC5N in the L1544 prestellar core. We derived a lower limit of 12C/13C &gt; 75 for the HC5N isotopologues, which does not allow to bring new constraints to the HC5N chemistry. Finally, we verified the impact of the revised reactions by running the GRETOBAPE astrochemical model. We found good agreement between the HC5N predicted and observed abundances in cold (∼10 K) objects, demonstrating that HC5N is mainly formed by neutral-neutral reactions in these environments. In warm molecular shocks, instead, the predicted abundances are a factor of ten lower with respect to observed ones. In this environment possessing an higher gas ionization fraction, we speculate that the contribution of ion-neutral reactions could be significant.
NEATH IV: an early onset of complex organic chemistry in molecular clouds
Authors: Priestley F D , Clark P C , Ragan S E , Scibelli S , Cusack M T , Glover S C O , Fehér O , Prole L R , Klessen R S 
Published: February 2025

ABSTRACT
Complex organic molecules (COMs) are widely detected in protostellar and protoplanetary systems, where they are thought to have been inherited in large part from earlier evolutionary phases. The chemistry of COMs in these earlier phases, namely starless and prestellar cores, remains poorly understood, as models often struggle to reproduce the observed gas-phase abundances of these species. We simulate the formation of a molecular cloud, and the cores within it, out of the diffuse interstellar medium, and follow the chemical evolution of the cloud material starting from purely atomic initial conditions. We find that the formation of both gas- and ice-phase COMs precedes the formation of cores as distinct objects, beginning at gas densities of a few $10^3 \, {\rm cm}^{-3}$. Much of this COM-enriched material remains at these relatively modest densities for several $\, {\rm Myr}$, which may provide a reservoir for accretion onto planet-forming discs in later evolutionary stages. We suggest that models of core and disc chemistry should not ignore the complex dynamical evolution which precedes these structures, even when studying supposedly late-forming molecules such as CH$_3$OH and CH$_3$CN.