bluuebunny/crossref_metadata_2025_split huggingface dataset:
A hybrid model for point and interval forecasting of agricultural price based on decomposition-ensemble and KDE
Authors: Zhang Dabin , Zhang Xuejing , Hu Huanling , Zhang Boting , Ling Liwen 
Published: October 2023

Abstract

Accurate and reliable price forecasting of agricultural products is significant for promoting the production and distribution of agricultural products, optimizing resource allocation and improving market efficiency. Due to the non-stationary feature in agricultural price, based on decomposition integration and kernel density estimation(KDE), this paper proposes a hybrid model for agricultural price forecasting that can quantify the uncertainty of potential forecasts by converting traditional point forecasts into interval forecasts. Firstly, the price sequence is decomposed through variational modal decomposition (VMD) determined by energy entropy (EE); secondly, K-means clustering is used to reconstruct the intrinsic modal functions (IMFs) into low-frequency components and high-frequency components, forecasted by different methods. In addition, adaptive kernel density estimation (AKDE) is established through dynamic window and whale optimization algorithm (WOA), which is used to construct prediction interval with the residual signal obtained by VMD. Finally, to validate the superiority of the proposed model, comparative experiments with three different datasets are conducted. The results show that prediction performance of the proposed model is better than other models in both point forecasts and interval forecasts, and it can provide more accurate uncertainty information to agricultural participants.
Collision dynamics modelling and testing of compliant buffering adsorption system under microgravity environment
Authors: Miao Yunfei , Tian Wei , Liao Wenhe , Duan Jinjun , Ye Jiaxuan 
Published: October 2023

Abstract

Contact collision has always been a very important and difficult problem in the fields of aerospace and mechanical engineering. The dynamics modelling and test of the impact collision process of the flexible buffering adsorption mechanism to a thin-walled plate under low-speed conditions in microgravity environment were studied. A multi-rigid-flexible coupling dynamics model of the entire system including the compliant buffering adsorption subsystem and the thin-walled plate subsystem was proposed by applying transfer matrix method for multibody systems, which has the advantages of not requiring the global dynamics equation of the system, low order of the system matrix, and high programming. The dynamics model of the thin-walled plate subsystem was modeled as a combination of mass-less beams and lumped mass to describe its flexible vibration characteristics. A nonlinear spring damping model is used to simulate the continuous collision force between the compliant buffer absorption subsystem and the thin-walled plate subsystem. Combined with the topology diagram of the system dynamics model, the overall transfer equation of the system is derived. A microgravity horizontal impact test platform was designed and established. Finally, the correctness and effectiveness of the proposed method were verified through the comparison of simulation and test results.
Building Trust and Partnership: Findings from A Needs Assessment of Military and Veteran Caregiving Families in Utah
Authors: Kalvesmaki Andrea , Bouldin Erin D. , Harrison Emily , Pugh Mary Jo 
Published: October 2023

Abstract

Identifying caregivers and their needs is a growing concern as overall, populations are aging and more care is provided at home rather than in clinical settings. Youth caregivers are underrecognized generally in the U.S. yet have become a priority to identify in Veteran caregiving families. However, little is known about this group and military and Veteran families may not readily self-identify due to stigma or fear of repercussions. A group of researchers affiliated with the Department of Veteran Affairs teamed with a community partner to conduct a needs assessment and town hall to better understand the caregiving needs of military and Veteran families in Utah, using a community-based research partnership approach. The largest area of need reported was special needs care for a child with disabilities younger than 18 (40%), followed by special needs care for a family member with disabilities 18 years or older (30%) and caregiver support for an older/senior family member (30%). A third of families indicated children aged 11 or younger and children aged 12–18 supporting caregiving activities at home. Many families reported multiple, overlapping needs In the town hall, families discussed the needs assessment and provided more detail on needs and family contexts. The results of the study are being used to design a caregiving support program hosted by the community partner and are informing a research strategy to better understand military and Veteran caregiving needs nationally.
Association Between the Early or Late Onset of Gestational Diabetes Mellitus with Neonatal Adverse Outcomes: A Retrospective Cohort Study
Authors: Reis Fabiana Vieira Duarte de Souza , Filho Carlos Izaias Sartorão , Sobrevia Luis , Prudencio Caroline Baldini , Bologna Bruna , Iamundo Luana Favaro , Takano Luis , Avramidis Raissa Escandiussi , de Oliveira Rafael Guilen , Rudge Marilza Vieira Cunha , Barbosa Angelica Mércia Pascon 
Published: October 2023

Abstract
Background
The significance of timing in diagnosing hyperglycemia during pregnancy and its association with adverse outcomes for the newborn is controversial. The literature has been evolving in standardizing gestational diabetes mellitus (GDM) diagnosis and terminology. we aimed to investigate the association between early-onset GDM and adverse outcomes in newborns and neonates, comparing it with the late-onset GDM model.
Methods
It was a retrospective cohort study at the Perinatal Diabetes Research Center-Assis affiliated nucleus from Botucatu Medical School-UNESP, Brazil, between 2016–2019. The group composition were, early-onset concerning participants with fasting glucose ≥ 92 mg/dL and < 126 mg/dL before 20 weeks of gestation or late-onset participants with negative first-trimester screening and positive 75g-OGTT at 24–28 weeks. The maternal baseline characteristics included: pre-pregnancy body mass index (BMI; Kg/m2); the pregnancy weight gain (Kg) calculated by the difference between final pregnancy weight (36 gestational weeks or more) and pre-pregnancy maternal weight and classified according to the pre-pregnancy BMI (8). In addition, the perinatal outcomes evaluated in this study were: gestational age (GA), birth weight (BW), and BW status according to GA as adequate, large or small, Apgar scores at the first and 5th minutes.
Results
Eight hundred eighty pregnant women were selected, 203 (23.07%) presenting GDM were eligible from December 2016 to December 2021. According to the timing onset of GDM, 89 (43.84%) were in the early-onset group and 114 (56.16%) in the late-onset group. the FPG values at the first trimester were higher in the early-onset group. The 75grams-OGTT values were higher in the late-onset group. The final BMI was higher in the late-onset group. A univariate linear regression was performed in order to determining relation between late-onset according different outcomes (Table 3), no significant relation was detected.
Conclusions
Pregnants with early-onset of GDM showed higher BMI during pregnancy, but there was no difference between the early or late-onset of GDM concerning neonatal adverser outcomes.
Electrophysiological and Behavioral Responses of Lygus hesperus Knight (Hemiptera: Miridae) to Host Plant Volatiles
Authors: Hetherington Matthew , Brunet Johanne , Nieto Diego , Ramirez Ricardo A. , Wenninger Erik J. , Guédot Christelle 
Published: October 2023

Abstract
Lygus hesperus Knight is a polyphagous pest of major concern to numerous cropping systems across western North America. Lygus hesperus exhibits well-documented host preferences which may be used to develop behavioral management strategies for this pest. This study sought to identify plant volatiles that mediate L. hesperus host preferences and assess the potential of those compounds to improve monitoring and management of this pest. Gas chromatography with electroantennographic detection was applied to identify antennally active compounds in headspace extracts from four host plants of varying attractiveness. Y-tube olfactometer assays were then conducted to determine L. hesperus responses to each of these 17 antennally active compounds individually. Six compounds attracted female L. hesperus, and subsequent tests revealed that females were attracted to an equal-parts blend of these six attractive compounds versus clean air, and that this blend was as attractive as flowering Medicago sativa. We then examined L. hesperus attraction to attractive compounds individually and an equal-parts blend of five attractive compounds in the field. An equal-parts blend of five attractive compounds was tested in strawberry, whereas the blend and each individual component were tested in alfalfa. In both field settings, neither the individual compounds nor the blend increased L. hesperus capture rates compared to unbaited control traps. Low attraction in the field could result from a masking effect of background volatiles or the failure to include important compounds in tested blends. It remains important to assess whether the compounds tested in this study may facilitate L. hesperus management in other cropping systems.
WITHDRAWN: Medical Student Perspectives on Safe Use of Non-English Language Skills in Patient Care: Effects of an Educational Intervention to Teach Self-Assessment Tools
Authors: Coto Maria Gabriela Valle , Pena Liset Garcia , Iñiguez Reniell X. , Giraldo Tatiana Betancur , Park Yoon Soo , Ortega Pilar 
Published: October 2023

Abstract

Introduction
The common practices of doctors “getting by” with limited language skills or using multilingual students/staff as ad hoc interpreters endanger care for populations with non-English language preference. We developed a session for medical students to learn to use two validated self-assessment tools: the Interagency Language Roundtable adapted for Healthcare (ILR-H) and the American Council on the Teaching of Foreign Languages Can-Do Statements.
Methods
All 179 first-year students at an urban medical school attended the session. Students used the ILR-H (a single item scaled from poor 1 to excellent 5) and Can-Do Statements (four items each scaled from novice 1 to distinguished 5) to self-report their skill level in any non-English language (multilingual students) and the minimum language level they believed necessary for safe patient care (all students). We analyzed correlations between ILR-H and Can-Do Statement self-ratings and differences in multilingual vs. monolingual student perspectives.
Results
Overall, 139 respondents (83%) were multilingual. Multilingual students’ mean ILR-H self-rating (2.36 [SD = 1.17]) and Can-Do Statements composite score (3.64 [SD = 2.32]) were strongly correlated (r = .91, p < .001). Post-session, fewer students felt ready to provide language-concordant care (32% [51/158] post vs. 41% [64/158] pre; p < .001). The mean ILR-H level reported by multilingual students as needed for safe patient care was 3.25 (SD = .94), higher than that reported by monolingual English speakers (2.57 [SD = 1.40]; p = .001).
Discussion
Teaching language self-assessment can enhance medical students’ critical awareness of the nuances of communicating with linguistically diverse patients. Future work should evaluate whether teaching self-assessment impacts clinical decision-making around language and interpreter use.
Genetic risk factors for bortezomib-induced peripheral neuropathy in an Asian population: A genome-wide association study in South Korea
Authors: Min Young Gi , Lee Sung-Yeoun , Lim Ehyun , Kim Dong-Ho , Byun Ja Min , Koh Youngil , Hong Junshik , Shin Dong-Yeop , Yoon Sung-Soo , Sung Jung-Joon , Oh Seog Bae , Kim Inho 
Published: October 2023

Abstract
Bortezomib-induced peripheral neuropathy (BIPN) poses a challenge in multiple myeloma (MM) treatment. Genetic factors play a key role in BIPN susceptibility, but research has predominantly focused on Caucasian populations. This research explored novel genetic risk loci and pathways associated with BIPN development in Korean MM patients, while evaluating reproducibility of variants from Caucasians. Clinical data and buffy coat samples from 185 MM patients on bortezomib were collected. The cohort was split into discovery and validation cohorts through random stratification of clinical risk factors for BIPN. GWAS was performed on the discovery cohort (n = 74) with Infinium Global Screening Array-24 v3.0 BeadChip (654,027 SNPs). Relevant biological pathways were identified using pathway scoring algorithm (PASCAL). The top 20 SNPs were validated in the validation cohort (n = 111). Previously reported SNPs were validated in the entire cohort (n = 185). Pathway analysis of the GWAS results identified 31 relevant pathways, including immune systems and endosomal vacuolar pathways. Among top 20 SNPs from discovery cohort, 16 were replicated, which included intronic variants in ASIC2 and SMOC2, recently implicated in nociception, as well as intergenic variants or long non-coding RNAs. None of the 17 previously reported SNPs remained significant in our cohort (rs2274578, p = 0.085). This study represents the first investigation of novel genetic loci and biological pathways associated with BIPN occurrence. Our findings, in conjunction with existing Caucasian studies, expand the understanding of personalized risk prediction and disease mechanisms.
LncRNA AP000842.3 Triggers the Malignant Progression of Prostate Cancer by Regulating Cuproptosis Related Axis
Authors: Zhou Gaobo , Chen Chaoqian , Wu Hongjian , Lin Jiao , Liu Hang , Tao Yiran , Huang Bin 
Published: October 2023

Abstract
Background
LncRNAs and miRNAs have significant regulatory roles in prostate cancer (PRAD) through the ceRNA network. Cuproptosis is a unique form of programmed cell death that is involved in various signaling pathways and biological processes related to tumor development. NFAT5, a transcription factor that activates T cells, has been implicated in cuproptosis. In this study, we aimed to determine the mechanism by which NFAT5 is involved in the regulation of ceRNA networks in prostate cancer.
Methods and results
The ceRNA network related to the survival of PRAD related genes was constructed by bioinformatics. Dual-luciferase reporter assay, CCK-8 and other experiments were used to prove the conclusion. The regulatory network of ceRNA was constructed by the differentially expressed lncRNA and miRNA and the mRNA after cuproptosis clustering analysis, and it was found that miR-206/NFAT5 may be an important ceRNA axis in the regulation of PRAD. We found that changes in AP000842.3 and miR-206 expression may affect PRAD proliferation through regulation of NFAT5. Mechanistically, AP000842.3 acts as the ceRNA of miR-206 to regulate the expression of NFAT5. The effects of lncRNA AP000842.3 on the malignant progression of PRAD and NFAT5 were partly dependent on miR-206.
Conclusions
In conclusion, we successfully filtered out that lncRNA AP000842.3, as a ceRNA of miR-206, is involved in regulating the level of cuprotosis-associated transcription factor NFAT5 in PRAD.
Assessment of Salivary Microbiota Profile as a Potential Diagnostic Tool for Pediatric Celiac Disease
Authors: Noruzpour Asal , Gholam-Mostafaei Fahimeh Sadat , Looha Mehdi Azizmohammad , Dabiri Hossein , Ciacci Carolina , Ahmadipour Shokoufeh , Rouhani Pejman , Nejad Mohammad Rostami 
Published: October 2023

Abstract

The association between oral dysbiosis and celiac disease (CD) remains poorly understood, as does the impact of CD-associated dysbiosis on disease development or exacerbation. This study aims to investigate alterations in salivary microbial composition among children with CD. In this cross-sectional study, saliva samples from 12 children with active CD (A-CD group), 14 children with CD on a gluten-free diet, and 10 healthy control children were analyzed using DNA sequencing targeting the 16S ribosomal RNA. Patients with CD exhibited a significant increase (p=0.00) in the Bacteroidetesphylum, while the Actinobacteria phylum showed a significant decrease (P=0.00). Notably, the Rothia genus and R.aeria also demonstrated a significant increase (P=0.00) within the CD group. Additionally, the control group displayed a significant increase (P=0.006) in R.mucilaginosaspecies compared to both CD patient groups.
Distinct bacterial strains were abundant in the saliva of patients with active CD, indicating a unique composition of the salivary microbiome in individuals with CD. These findings suggest that our approach to assessing salivary microbiota changes may contribute to developing noninvasive methods for diagnosing and treating CD.
Research on Heart and Lung Sound Separation Method Based on DAE-NMF-VMD
Authors: sun wenhui , CHEN Fuming , ZHANG Yipeng , CHEN Fenlan 
Published: October 2023

Abstract

Auscultation is the most effective method for diagnosing cardiovascular and respiratory diseases. However, stethoscopes typically capture mixed signals of heart and lung sounds, which can affect the auscultation effect of doctors.Therefore, the efficient separation of mixed heart and lung sound signals plays a crucial role in improving the diagnosis of cardiovascular and respiratory diseases. In this paper, we propose a blind source separation method for heart and lung sounds based on Deep Autoencoder (DAE), Non-Negative Matrix Factorization (NMF), and Variational Mode Decomposition (VMD).Firstly, DAE is employed to extract highly informative features from the heart and lung sound signals. Subsequently, NMF clustering is applied to group the heart and lung sounds based on their distinct periodicities, achieving the separation of the mixed heart and lung sounds. Finally, Variational Mode Decomposition is used for denoising the separated signals. Experimental results demonstrate that the proposed method effectively separates heart and lung sound signals and exhibits significant advantages in terms of standardized evaluation metrics when compared to Non-Negative Matrix Factorization methods and DAE-NMF algorithms without denoising.
Interactions between immune cell types facilitate the evolution of immune traits
Authors: Dubovik Tania , Lukačišin Martin , Starosvetsky Elina , LeRoy Benjamin , Normand Rachelly , Admon Yasmin , Alpert Ayelet , Ofran Yishai , G'Sell Max , Shen-Orr Shai S. 
Published: October 2023

Abstract

An essential prerequisite for evolution by natural selection is variation among individuals in traits that affect fitness1. The ability of a system to produce selectable variation, known as evolvability2, thus greatly affects the rate of its evolution. The immune system belongs to the fastest evolving components of mammalian genomes3, yet the sources of useful variation in immune traits remain largely unknown4,5. Here, we show that a key determinant of the immune system’s evolvability is its organisation into interacting modules represented by different immune cell types. By profiling immune cell variation in bone marrow of 54 genetically diverse mouse strains from the Collaborative Cross6, we found that variation in immune cell frequencies is polygenic and that associated genes are largely involved in quantitative homeostasis through cell-intrinsic functions of proliferation, migration and cell death. However, we also found that many genes influencing the frequency of a particular cell type are not expressed in that specific cell type, but rather in a different immune cell type. Vertebrate evolutionary record shows that genes implicated in this non-cell-intrinsic variation have faced fewer purifying constraints, indicating that they have acted as key determinants in the recent evolvability of immune traits. Our findings suggest that interactions between different components of the immune system provide a phenotypic space where mutations can produce selectable variation without much detriment, offering a solution to the robustness-evolvability conundrum2,7,8 in the context of the immune system.
Based on the RF model, the analysis of the influencing factors of the satisfaction of the highway differential charging policy is analyzed
Authors: 刘 拥华 , Ruikun Duan , 申 科 , Qingxiong Luan 
Published: October 2023

Abstract
In order to solve the problem that the impact of public satisfaction on the evaluation effect is less considered in the evaluation of the implementation effect of differentiated toll collection on expressways. Based on the satisfaction survey questionnaire of differentiated toll road sections in Yunnan Province in 2022, a random forest model (RF) under the two-category experiment was constructed to analyze the influencing factors of the satisfaction of expressway differentiated toll policy. The results show that the random forest model (RF) under the binary classification experiment has good fitting. At the same time, the satisfaction degree of timely and accurate preferential policies is the most important factor affecting the overall satisfaction of expressway differentiated charging policies, and its contribution degree is 20.35%. In addition, the independent effect analysis shows that the overall satisfaction of the differentiated charging method for empty trucks is the highest, and the overall satisfaction of the differentiated charging method for road sections is the lowest.
Effect of replacing soybean meal with dried Bovine blood meal on growth Performance, haematology and serum profile of SASSO birds
Authors: Salifu Abdul-Rahaman S. , Mamadu Halidu Agolisi , Nartey Ebenezer Kofi , Waltia Shirley Shena 
Published: October 2023

Abstract
The rising cost of processed feed has created a demand for more inexpensive feed options for chicken production. In most slaughterhouses, blood is thrown as trash, however, it can be used as a protein source. A study was conducted to assess the effect of replacing soybean meal with dry bovine blood meal on the growth performance and blood profile of SASSO birds. The treatments were as follows: control, 5% dry matter (DM), and 10%DM-DBBM. Chemical analysis revealed that the blood meal content contained 86.76% crude protein, 1.36% ether extract, 1.98% crude fibre, and 8.54% DM ash. Birds fed the 5% DM-DBBM diet had the highest daily DM intake (80.35%). The final weight and daily weight gain increased significantly (P < 0.05) with increasing DBBM levels. Birds fed the 10%DM-DBBM diet exhibited the best feed conversion. All haematological and serum profile parameters studied were within the normal physiological ranges. It was concluded that dried bovine blood meal supplementation of up to 10% had no adverse effects on dry matter intake, daily weight gain, growth performance, and blood parameters of SASSO birds.