bluuebunny/crossref_metadata_2025_split huggingface dataset:
Coffee Grounds as Renewable Filler in NBR Biocomposites
Authors: Öncel Şehriban , Ünügül Tuba , ABACI Ufuk , Karaağaç Bağdagül 
Published: November 2023

Abstract
Using biological/renewable resources as filler or modifier in both thermoplastics and rubbers has been of a great interest in order to reduce negative effects of traditional petroleum/natural gas based fillers. In this study, the main goal was the use of spent (waste) coffee grounds as a natural alternative filler to carbon black in acrylonitrile butadiene rubber (NBR) based compounds. Stabilization effect of fresh coffee grounds was also investigated. Both fresh and spent coffee grounds were gradually replaced with CB in a reference (control) NBR compound formulation. Rheological, physico-mechanical, thermal, morphological, and dielectric properties of the biocomposites were tested and compared with the control. Processability has been affected positively in the case of using coffee grounds thanks to the presence of triacyl groups in coffee. Improved abrasion resistance and lower oil swelling could be obtained for coffee containing compounds. In conclusion, spent coffee grounds were found to be a good natural alternative filler for preparing NBR based biocomposites without a significant change in material properties.
Numerical Simulation for Marangoni Convective Transport of Electro MHD flow of second grade fluid through Cattaneo-Christov heat and mass fluxes over an exponentially stretching surface
Authors: Gupta Sumit , Sangtani Virendra , Jain Chandra Prakash , Jain Pawan Kumar 
Published: November 2023

Abstract
This paper addresses the Bernard-Marangoni convectively flow of Electrically Magneto Hydrodynamic (EMHD) second grade fluid over an exponentially stretching surface. Fluid motion is produced owing to the temperature and soluble gradient difference, hence Marangoni effects occurs if there is an archetypally deviations of surficial tensions at the two-phase interface. Flow is encouraged by non-Fourier heat flux perception. Impact of thermo-diffusion and diffusion-thermo are also incorporate in this study. Using the suitable transformation, the system of partial differential equations is discretized to nonlinear ordinary differential equations. The Maple built-in BVP mid rich technique applied to solve these equations. Impact study of entrenched physical non-dimensional parameter over the velocity, temperature and concentration profile are analyzed graphically and a comparative study also discussed with the existing literature. The local friction coefficient, Nusselt number and Sherwood numbers are employed in this study. The current work can also be considered as an extensive works in numerous branches of science and engineering.
Acceptability and usability of early digital health rehabilitation after cardiac surgery in the elderly: a qualitative study
Authors: Toft Bente Skovsby , Rodkjaer Lotte Ørneborg , Sørensen Lotte , Saugbjerg Marianne Rørbaek , Bekker Hilary Louise , Modrau Ivy Susanne 
Published: November 2023

Abstract
Background: Increasing numbers of elderly patients experience prolonged decreased functional capacity and impaired quality of life after seemingly successful cardiac surgery. After discharge from hospital, these patients experience a substantial gap in care until centre-based cardiac rehabilitation commences. They may benefit from immediate coaching by means of mobile health technology to overcome psychological and physiological barriers to physical activity. The aim of this study was to explore the usability, acceptability, and relevance of a mobile health application designed to support remote exercise-based cardiac rehabilitation of elderly patients early after cardiac surgery from the perspective of patients, their relatives, and physiotherapists.
Methods: We adapted a home-based mobile health application for use by elderly patients early after cardiac surgery. Semi-structured dyadic interviews were conducted with a purposive sample of patients (n=9), their spouses (n=5), and physiotherapists (n=2) following two weeks of the intervention. The transcribed interviews were analysed thematically.
Results: Three themes were identified: 1) creating an individual fit by tailoring the intervention; 2) prioritizing communication and collaboration; and 3) interacting with the mobile health application. Overall, the findings indicate that the mobile health intervention has the potential to promote engagement, responsibility, and motivation among elderly patients to exercise early after surgery. However, the intervention can also be a burden on patients and their relatives when roles and responsibilities are unclear.
Conclusion: The mobile health intervention showed potential to bridge the intervention gap after cardiac surgery, as well as in fostering engagement, responsibility, and motivation for physical activity among elderly individuals. Nevertheless, our findings emphasize the necessity of tailoring the intervention to accommodate individual vulnerabilities and capabilities. Tailoring the intervention is essential to accommodate individual vulnerabilities and capabilities. The intervention may be improved by addressing a number of organizational and communicational issues. Adaptions should be made according to the barriers and facilitators identified in this study prior to testing the effectiveness of the intervention on a larger scale. Future research should focus on the implementation of a hybrid design that supplements or complements face-to-face and centre-based cardiac rehabilitation.
Trial registration: Danish Data Protection Agency, Central Denmark Region (1-16-02-193-22, 11 August 2022).
Recent Advances on the Synthesis of Orally Active Antiviral Drug Molnupiravir
Authors: Sahoo Tanmoy , Reddy Basi V. Subba 
Published: November 2023

Abstract:
Molnupiravir is one of the simple orally active antiviral drugs, sold under the
brand name Lagevrio. Initially, this drug was used to treat the influenza virus but later on,
used against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This is the
first orally active and direct-acting antiviral drug and is highly effective against SARS-CoV-
2. In this review, we discuss different synthetic strategies for the synthesis of molnupiravir,
which will help for the further development of novel routes.
An Open-label Exploratory Study Investigating BDNF Essentials® on
Cognition in Healthy Adults with Self-reported Memory Complaints
Authors: Lewis Erin D. , Crowley David C. , Hamilton Debby , Guthrie Najla , Evans Malkanthi 
Published: November 2023

Background::
An open-label, exploratory study has been conducted to investigate the ef-ficacy of BDNF Essentials® for cognitive function and neurological health.

Methods::
Twenty healthy adults ≥45 years of age, with a score ≥24 on the Mini-Mental State Ex-amination (MMSE-2) and self-reported memory complaints were supplemented with BDNF Es-sentials® for 84 days. Computerized Mental Performance Assessment System (COMPASS) tests for memory, attention, and processing speed were conducted, and change in plasma brain-derived neurotrophic factor (BDNF), Profile of Mood States (POMS), the Healthy People Sleep Quality Index (HPSQI), perceived stress scale (PSS), and salivary cortisol, interleukin (IL)-6, and tumour necrosis factor-α (TNF-α) were assessed at baseline and days 28, 56, and 84.

Results::
Supplementation with BDNF Essentials® significantly increased COMPASS tests for memory, attention, and processing speed (all P<0.05). Salivary cortisol was found to be signifi-cantly decreased at days 56 and 84, and IL-6 at day 84 (P<0.05). A reduction in depression-dejection at day 56 and in confusion-bewilderment at day 84, and an improvement in sleep satis-faction at day 56 (all p<0.05) were reported.

Conclusion::
BDNF Essentials® improved reaction time in measures of working memory, episodic memory, and attention, reduced biomarkers of stress and inflammation, and improved mood and sleep. BDNF Essentials® has been found to be safe and well-tolerated in adults with self-reported memory complaints.
Gênero e Sexualidade de Jovens com TEA
Authors: Antunes do Nascimento Clarice , Ribeiro Vargas Juliana , Duarte Bezerra Kay 
Published: November 2023

RESUMO
Buscamos analisar, neste texto, narrativas de jovens autistas sobre as dimensões do gênero e da sexualidade na exibição do podcast Introvertendo. De modo mais específico, interessa-nos problematizar experiências afetivas e sexuais vivenciadas pelos jovens produtores do referido podcast. Para tanto, em uma abordagem pós-estruturalista, apoiamo-nos nos campos teóricos nos Estudos Culturais em Educação, nos Estudos de Gênero e Sexualidade e Estudos sobre Juventudes. Como metodologia, utilizamos a netnografia, analisando os episódios que tinham como tema central relacionamentos e experiências afetivas sexuais dos produtores do podcast, os quais identificam-se como sujeitos com TEA (transtorno do espectro autista). Como resultados, destacamos que, apesar da invisibilidade do tema, o podcast em questão atua como uma pedagogia cultural, (re)educando jovens autistas em inúmeras dimensões e, entre essas, o gênero e a sexualidade, fazem-se presentes.
The Usefulness of Web-Based Communication Data for Social Network Health Interventions: Agent-Based Modeling Study
Authors: Blok David J , Simoski Bojan , van Woudenberg Thabo J , Buijzen Moniek 
Published: November 2023

Background
Social network interventions are an effective approach to promote physical activity. These interventions are traditionally designed using self-reported peer nomination network data to represent social connections. However, there is unexplored potential in communication data exchanged through web-based messaging apps or social platforms, given the availability of these data, the developments in artificial intelligence to analyze these data, and the shift of personal communication to the web sphere. The implications of using web-based versus offline social networks on the effectiveness of social network interventions remain largely unexplored.

Objective
This study aims to investigate the differences in the impact of social network interventions on physical activity levels (PALs) between networks derived from web-based communication and peer nomination data.

Methods
We used the data on sociometric questionnaires, messages from a web-based communication app, and PAL (number of steps per day) of 408 participants in 21 school classes. We applied social network analysis to identify influential peers and agent-based modeling to simulate the diffusion of PAL and explore the impact of social network interventions on PAL among adolescents in school classes. Influential peers (n=63) were selected based on centrality measures (ie, in-degree, closeness, and betweenness) to spread the intervention. They received health education, which increased their PAL by 17%. In sensitivity analyses, we tested the impact of a 5%, 10%, and 20% increase in PAL among influential peers.

Results
There was a 24%-27% overlap in selected influential peers between the 2 network representations. In general, the simulations showed that interventions could increase PAL by 5.0%-5.8% within 2 months. However, the predicted median impact on PAL was slightly higher in networks based on web-based communication data than peer nomination data for in-degree (5.7%, IQR 5.5%-6.1% vs 5.5%, IQR 5.2%-5.8%; P=.002), betweenness (5.6%, IQR 5.4%-5.9% vs 5.0%, IQR 4.7%-5.3%; P<.001), and closeness centrality (5.8%, IQR 5.6%-6.1% vs 5.3%, IQR 5.0%-5.6%; P<.001). A large variation in impact was observed between school classes (range 1.5%-17.5%). Lowering the effectiveness of health education from 17% to 5% would reduce the overall impact of the social network intervention by 3-fold in both networks.

Conclusions
Our findings showed that network interventions based on web-based communication data could increase PAL. Web-based communication data may therefore be a valuable addition to peer nomination data for future social network intervention design. Artificial intelligence methods, including agent-based modeling, can help to design these network interventions and provide insights into the role of network characteristics in their effectiveness.
The Relationship Between Cognitive Resource Consumption During Gameplay and Postgame Aggressive Behaviors: Between-Subjects Experiment
Authors: Teng Huina , Zhu Lixin , Zhang Xuanyu , Qiu Boyu 
Published: November 2023

Abstract

Background
The question of how video games can shape aggressive behaviors has been a focus for many researchers. Previous research has focused on how violent video game content leads to postgame aggressive behaviors. However, video games not only convey violence or prosocial content to players but also require cognitive effort from individuals. Since human cognitive resources are limited, consuming more cognitive resources in a game leads to less cognitive resources to suppress aggressive impulses. Therefore, the depletion of cognitive resources from playing video games may also lead to changes in postgame aggressive behaviors.

Objective
This study aimed to examine the relationship between cognitive resources consumed in video games and postgame aggressive behaviors.

Methods
A total of 60 participants (age: mean 20.22; range 18-24 y) were randomly assigned to either the high-load group or the low-load group. Participants from both groups played a video game centered around college life. In the low-load group, participants followed the gameplay instructions to complete it. In the high-load group, participants were given an extra digital memory task to complete while playing the game. Participants in both groups played the video game for about 25 minutes. A maze selection task was then conducted to measure the participants’ helping and hurting behaviors.

Results
The independent samples 2-tailed t tests showed that the high-load group had significantly higher hurting scores (mean 3.13, SD 2.47) than the low-load group (mean 1.90, SD 2.12; t58=−2.07, P=.04; Cohen d=−0.535), whereas helping behaviors were not significantly affected (t58=1.52, P=.13; Cohen d=0.393).

Conclusions
As more cognitive resources are consumed in a video game, more hurting behaviors are exhibited after the game. This finding proposes an alternative route by which video games impact aggressive behaviors, adding to previous theories and raising concerns about the popularity of cognitive training games.
A Mobile Health App for Facilitating Disease Management in Children With Atopic Dermatitis: Feasibility and Impact Study
Authors: Zvulunov Alex , Lenevich Stepan , Migacheva Natalia 
Published: November 2023

Background
Inadequate control of atopic dermatitis (AD) increases the frequency of exacerbations and reduces the quality of life. Mobile health apps provide information and communication technology and may increase treatment adherence and facilitate disease management at home. The mobile health app, Atopic App, designed for patients and their caregivers, and the associated web-based patient education program, Atopic School, provide an opportunity for improving patients’ and caregivers’ engagement and adherence to the management of AD.

Objective
This noninterventional, observational study aimed to explore the feasibility and potential impact on the management of AD in children by caregivers using the Atopic App mobile health app.

Methods
The patient-oriented eczema measure (POEM) and numerical rating scale for the grading of pruritus were used as severity scores (scale range: 0-28). The artificial intelligence model of the app was used to assess the severity of AD based on the eczema area and severity index approach. The deidentified data enabled the analysis of the severity of AD, treatment plan history, potential triggers of flare-ups, usage of available features of the app, and the impact of patient education.

Results
During a 12-month period, of the 1223 users who installed the app, 910 (74.4%) registered users were caregivers of children with AD. The web-based Atopic School course was accessed by 266 (29.2%) caregivers of children with AD, 134 (50.4%) of whom completed the course. Usage of the app was significantly more frequent among those who completed the Atopic School program than among those who did not access or did not complete the course (P<.001). Users who completed a second POEM 21 to 27 days apart exhibited a significant improvement of AD severity based on the POEM score (P<.001), with an average improvement of 3.86 (SD 6.85) points. The artificial intelligence severity score and itching score were highly correlated with the POEM score (r=0.35 and r=0.52, respectively).

Conclusions
The Atopic App provides valuable real-world data on the epidemiology, severity dynamics, treatment patterns, and exacerbation-trigger correlations in patients with AD. The significant reduction in the POEM score among users of the Atopic App indicates a potential impact of this tool on health care engagement by caregivers of children with AD.
“I Just Wanted a Dentist in My Phone”—Designing Evidence-Based mHealth Prototype to Improve Preschool Children’s Oral and Dental Health: Multimethod Study of the Codevelopment of an App for Children’s Teeth
Authors: Al-yaseen Waraf , Raggio Daniela Procida , Araujo Mariana , Innes Nicola 
Published: November 2023

Background
Dental caries in preschool children is a global health concern. With increased access to technology and the disruption of health care during the pandemic, mobile health apps have been of interest as potential vehicles for individuals’ health maintenance. However, little is known about caring for their child’s teeth and what their preferences would be regarding the content or design of an oral health app.

Objective
This study aims to co-design the prototype of an app named App for Children’s Teeth with parents, providing a source of information for them about caring for their children’s teeth and promoting positive dental habits.

Methods
This multimethod study conducted user involvement research with a purposive sample of parents or carers of children aged ≤6 years to (1) understand their use of the internet through the eHealth Literacy Scale and interviews, (2) determine their opinions about content related to children’s oral health, and (3) collect feedback about the app’s acceptability using the Theoretical Framework of Acceptability. There were three stages: (1) interviews with parents to understand their needs, preferences, and abilities; (2) prototype design with app developers; and (3) parent feedback interviews using the think aloud method for data collection. Data were deductively analyzed using a codebook strategy, whereas data from the think aloud sessions were analyzed inductively using reflexive thematic analysis.

Results
The prototype design stage involved 10 parents who reported using the internet for health information but found it to be scattered and contradictory. Parents generally welcomed the App for Children’s Teeth but expressed concerns about screen time and practicality. They suggested guidance regarding oral hygiene practices, teething symptoms, and pain relief. Parents appreciated features such as clear fonts, categorization according to their child’s age, and “In a Nutshell” bullet points. Topics that resonated with parents included information about teething, finding a dentist, and breastfeeding. They believed that the app aligned with their goals and offered suggestions for future developments, such as outlining the process of finding a dentist and incorporating a forum for parents to communicate and exchange ideas.

Conclusions
The coproduction design approach highlighted parents’ need for solutions such as mobile health apps to access reliable information about oral health. Parents identified key design concepts for the app, including a simple and uncluttered interface, content categorization according to their child’s age, and practical guidance supported by visual aids. Despite potential challenges related to screen time restrictions, parents provided insights into how such an app could fit seamlessly into their lives.

Trial Registration
Open Science Framework; https://osf.io/uj9az
A Child Rights Perspective on Babies Behind Bars: An analysis of two different narratives and their outcomes
Authors: Letkeman Kristen 
Published: November 2023

Abstract:
This comic represents two narrative outcomes of the Mother-Child Program for Federally Incarcerated Women in Canada resulting in child rights concerns for this growing population of children. The Mother-Child Program has stringent policies related to corresponding documents that those who are wanting to participate in the Mother-Child Program must adhere to. Those who are requesting the Mother-Child Program rely on other service providers to submit their paperwork within tight timeframes, in order to be considered. The comic illustration represents the detrimental result of the failure of a social worker not presenting their mandatory documents in the time frame allowed, which denies the applicants submission to the Mother-Child Program. The stringent policies of the Mother-Child Program and its' consequences are outlined throughout the adverse childhood effects that parental incarceration has on a child and the difficulties those incarcerated face in maintaining a strong attachment to their child due to policy barriers. The lack of sense of identity and belonging for this population of children is reflected in the narratives of the comic and growing discrimination for this population of children is evidenced through the analysis that follows the comic illustration.
The second comic represents a mother and child who are accepted into the Mother-Child Program and the positive effects that the Mother-Child Program has on the bond within mother and child. It is important to note that the Mother-Child Program is a voluntary program for applicants and for some mothers, who meet the criteria, a suitable program. Not all mothers are given this program as an option due to the various natures of criminal charges. The intent of this comic is to represent the difficulties that policy barriers place on those wishing to access a program that they are suitable for and the devastating consequences when an application is denied due to policy implementation. The narratives included in this comic are assumed conversations reflecting the evidence of positive outcomes for those who experienced the Mother-Child program as well as the negative consequences of those who are denied access to the program through literature review. The calls to action and advocacy required for this group of children falling into systemic invisibility due to the inaction of systemic government programs are direct violations of children’s rights. In order for a better world fit for children, action, advocacy and systemic change are required to address the injustices this group of children face.
Key terms: Children of Incarcerated Parents, Adverse Childhood Experiences, Attachment, Canadian Policy, Child Rights