bluuebunny/crossref_metadata_2025_split huggingface dataset:
Recovery of Neurophysiological Measures in Post-COVID Fatigue – a 12-month Longitudinal Follow-up Study
Authors: Maffitt Natalie J. , Germann Maria , Baker Anne M.E. , Baker Mark R. , Baker Stuart N. , Soteropoulos Demetris S. 
Published: November 2023

AbstractOne of the major consequences of the COVID-19 pandemic has been the significant incidence of persistent fatigue following resolution of an acute infection (i.e. post-COVID fatigue). We have shown previously that, in comparison to healthy controls, those suffering from post-COVID fatigue exhibit changes in muscle physiology, cortical circuitry, and autonomic function. Whether these changes preceded infection, potentially predisposing people to developing post-COVID fatigue, or whether the changes were a consequence of infection was unclear. Here we present results of a 12-month longitudinal study of 18 participants from the same cohort of post-COVID fatigue sufferers to investigate these correlates of fatigue over time. We report improvements in self-perception of fatigue via questionnaires, as well as significant improvements in objective measures of peripheral muscle fatigue and autonomic function, bringing them closer to healthy controls. Additionally, we found reductions in muscle twitch tension rise times, becoming faster than controls, suggesting that the improvement in muscle fatigability might be due to a process of adaptation rather than simply a return to baseline function.
Longitudinal Analysis of Step Counts in Parkinson’s Disease Patients: Insights from a Web-Based Application
Authors: Gong Yishu , Wang Yuli , Wang Ziyang , Li Xin , Gu Yuan 
Published: November 2023

AbstractParkinson’s disease (PD) is a chronic neurological disorder that affects millions of people worldwide. One of the common motor symptoms associated with PD is gait impairment, leading to reduced step count and mobility. Monitoring and analyzing step count data can provide valuable insights into the progression of the disease and the effectiveness of various treatments. The generalized additive model (GAM) model presents the following variables: sex (Male vs. Female, p = 0.03), handedness (Right vs. Left/Both, p = 0.015), PD status of father (Yes vs. No, p = 0.056), COVID-19 status (Yes vs. No, p = 0.008), cohort (PD vs. healthy control, p < 0.0001), the cubic regression spline with three basis functions of age by cohorts (p<0.0001) and the random effect of the individual age trajectories (p = 0.0001) are statistically significant for daily step counts. A web application specifically tailored for step count analysis in PD patients was also developed and it provides a user-friendly interface for patients, caregivers, and healthcare professionals to track and analyze step count data, facilitating personalized treatment plans and enhancing the management of PD.
Analysis of thermsolutal performance and entropy generation for ternary hybrid nanofluid in a partially heated wavy porous cabinet
Authors: Hansda Samrat , Chattopadhyay Anirban , Pandit Swapan K. 
Published: November 2023

Purpose
This study comprehensively examines entropy generation and thermosolutal performance of a ternary hybrid nanofluid in a partially active porous cabinet. The purpose of this study is to comprehend the intricate phenomena of double diffusion by investigating the dispersion behavior of Al2O3, CuO, and Ag nanoparticles in water.

Design/methodology/approach
The cabinet design consists of two horizontal walls and two curved walls with the lower border divided into a heated and concentrated region of length b and the remaining sections are adiabatic. The vertical borders are cold and low concentration, while the upper border is adiabatic. Two cavity configurations such as convex and concave are considered. A uniform porous medium is taken within the ternary hybrid nanofluid. This has been characterized by the Brinkman-extended Darcy model. Thermosolutal phenomena are governed by the Navier-Stokes equations and are solved by adopting a higher-order compact scheme.

Findings
The present study focuses on exploring the influence of several well-defined parameters, including Rayleigh number, Darcy number, Lewis number, Buoyancy ratio number, nanoparticle volume concentration and heater size. The results indicate that the ternary hybrid nanofluid outperforms both the mono and hybrid nanofluids in all considered aspects.

Originality/value
This study brings forth a significant contribution by uncovering novel flow features that have previously remained unexplored. By addressing a well-defined problem, the work provides valuable insights into the enhancement of thermal transport, with direct implications for diverse engineering devices such as solar collectors, heat exchangers and microelectronics.
Legitimacy of power exercised by FATF under international law
Authors: Otudor Lovina E. , Bagheri Mahmood 
Published: November 2023

Purpose
This study aims to focus on the legal status of the Financial Action Task Force (FATF) regulatory spread in spite of its limited membership in international law. This is conducted by examining the regime of the FATF with the normative regime of public international law and trying to identify common grounds and conflicts between the two.

Design/methodology/approach
This study adopted an exploratory approach involving a thorough examination and analysis of accredited text, command papers and reports, archival materials, national obligations, websites as well as other documentary evidence.

Findings
This research gives an empirical determinant of compliance behaviour in response to FATF regulatory standards and the interplay of international law.

Research limitations/implications
The findings here are not exhaustive and could be approached from other perspectives. Researchers are therefore encouraged to engage by testing the findings further, as this is only a blueprint for further research.

Practical implications
This study provides implications for the need to open up the current membership of the FATF, as it appears discriminatory in nature and could inhibit effective compliance with its regulatory standards.

Social implications
FATF regulatory standards do not just revolve around its members and rule-takers but also affect unintended and vulnerable people who were never in contemplation when these regulations were debated without a global consensus.

Originality/value
The main aim of this study is to advocate for a rethink of FATF’s regulatory strategy by ensuring that its operations are more inclusive, where jurisdictions can participate as members, creating a sense of belonging and commitment in the fight against money laundering.
Social media visibility and intellectual capital disclosure. An empirical analysis in the basketball clubs
Authors: L’Abate Vitiana , Raimo Nicola , Rubino Michele , Vitolla Filippo 
Published: November 2023

Purpose
The sport industry, due to the great importance of intangible assets, represents a field of particular interest for the analysis of intellectual capital disclosure (ICD). However, this sector is still underexplored in the academic literature. This study aims to fill this gap by analysing the level of intellectual capital (IC) information disclosed by the most important basketball clubs on their website and the factors capable of influencing the dissemination of such information. Specifically, it examines the impact of social media visibility – in terms of number of social networks, number of posts, number of followers and internet visibility – on the ICD level.

Design/methodology/approach
Firstly, this study performs a manual content analysis of the websites of the top 80 European and US basketball clubs aimed at analysing the ICD level. Secondly, it provides for a regression analysis to test the impact of social media visibility on the amount of IC information disclosed.

Findings
Empirical results show a low level of ICD among the basketball clubs examined. They also demonstrate the positive impact of number of posts, number of followers and internet visibility on the amount of IC information disclosed online.

Originality/value
This study extends the analysis of the ICD to the sport industry, still little examined by the academic literature. In this regards, to the best of the authors’ knowledge, this is the first study to explore the ICD in the basketball industry.
Plant biodiversity responds more strongly to climate warming and anthropogenic activities than microbial biodiversity in the Qinghai–Tibetan alpine grasslands
Authors: Shangguan Zijian , Jing Xin , Wang Hao , Liu Huiying , Gu Huijie , He Jin‐Sheng 
Published: November 2023

Abstract

Biodiversity serves as the fundamental underpinning for ecosystem functions and services. As a result of human‐induced global change, there is a growing awareness of the substantial alterations in terrestrial above‐ground biodiversity, particularly within alpine regions. However, it remains uncertain whether below‐ground biodiversity will exhibit similar responses, both in terms of magnitude and manner, to anthropogenic global changes as above‐ground biodiversity.

Here, we conducted a meta‐analysis to assess the impacts of warming, nutrient addition and grazing on plant and soil microbial biodiversity in alpine grasslands on the Qinghai–Tibetan Plateau, which are known to be climate‐sensitive and vulnerable. The analysis included 819 experimental observations from 152 studies, focussing on species richness, Shannon diversity and Pielou's evenness.

We found that plant biodiversity exhibited greater sensitivity to climate warming and anthropogenic activities compared with soil microbial biodiversity. Specifically, plant richness and Shannon diversity were reduced by warming and nutrient addition, while plant evenness was increased by grazing. However, only microbial richness was increased by grazing and microbial evenness was increased by warming slightly.

The responses of biodiversity to climate warming and anthropogenic activities were modulated by multiple factors. Specifically, the negative effects of warming on plant biodiversity were more pronounced in long‐term experiments under warmer or drier environmental conditions. The negative effects of nitrogen addition on biodiversity were enhanced by the intensity and duration of nitrogen treatment. Appropriate intensity and frequency of grazing were beneficial to sustaining plant biodiversity. Soil microbial biodiversity was weakly regulated, where bacterial Shannon diversity was more sensitive to nutrient addition, while fungal species richness was sensitive to grazing.

Synthesis. Our findings reveal a mismatch between above‐ground plant and below‐ground microbial biodiversity in response to climate warming and anthropogenic activities in alpine grasslands, with plant biodiversity being more sensitive. In the context of future global change, plant biodiversity may be at greater risk than soil microbial biodiversity. In addition, biodiversity responses of different experimental and environmental conditions should be distinguished, and more attention is needed on biodiversity conservation in alpine steppe, or areas with warmer and drier environmental conditions, high‐intensity fertilization or heavy grazing.
The New Responsive Constitutionalism
Authors: Dixon Rosalind 
Published: November 2023

Ideas of responsive law and regulation have been the subject of sustained scholarly attention but only recently have scholars turned their attention to what these ideas mean for constitutional law and governance. The article addresses this gap in the literature by exploring the idea of responsiveness in constitutional design and interpretation. It suggests that the idea of responsive constitutionalism points to the importance of both unwritten and written, and politically and judicially‐enforced, constitutional norms in promoting democratic responsiveness. In turn, responsive constitutionalism also reinforces the value of: (1) institutional pluralism; (2) overlapping institutional authority; (3) multiple access points to institutions; and (4) broad remedial power for relevant institutions, including courts. It further suggests the need for a true balance between constitutional norms that promote rights‐enhancing forms of state action and limits on state action. And finally, it points to the value of strong institutional checks and balances and entrenchment of the ‘minimum core’ of a democratic constitution, but a more flexible set of constraints in other contexts, where the aim of a responsive constitutional model is to promote dialogue between courts and legislators. The article explores these ideas by reference to existing constitutional theoretic ideas but also through illustrations drawn from Australia, Kenya and the United Kingdom.
Habitat selection by Grevy's zebra (Equus grevyi): Conservation implications
Authors: Kirathe Joseph Nderitu , Githaiga John Maina , Chira Robert Mutugi , Rubenstein Daniel I. 
Published: November 2023

AbstractUnderstanding the spatial dynamics of landscape use by free‐ranging herbivores is essential for species management and conservation in its natural environment. We used Ivelv’s selection index, binary logistic regression analyses and stepwise regression to understand how environmental factors shape habitat selection by the Grevy’s zebra (Equus greyvi). We measured biotic, abiotic and human factors that may influence presence or absence of Grevy’s zebra in Samburu‐Laikipia landscape and showed: (1) during wet periods, percentage perennial grasses, livestock density and grass quality had the greatest effect on Grevy’s zebra presence; but (2) during dry weather periods a different suite of factors determined their landscape distribution, namely, the percentage of tree and bush density, distance to water and overall grass abundance. In addition, different Grevy’s zebra demographic and reproductive classes varied in their response to environmental selective forces, thus demonstrating flexibility in their patterns of habitat selection. While we recommend more detailed studies on how abiotic and biotic interact to shape habitat selection patterns, our findings underscored the need of maintaining both dry and wet season habitats to ensure essential grazing area refugia. Our findings show that ‘soft’ development with controlled livestock stocking rates within the landscape will enhance Grevy’s zebra conservation.
Influence of the type of anatomic resection on anastomotic leak after surgery for colon cancer
Authors: Ng Suat Chin , McCombie Andrew , Frizelle Frank , Eglinton Tim 
Published: November 2023

AbstractIntroductionAnastomotic leak (AL) after colon cancer resection is feared by surgeons because of its associated morbidity and mortality. Considerable research has been directed at predictive factors for AL, but not the anatomic type of colonic resection. Anecdotally, certain types of resection are associated with higher leak rates although there remains a paucity of data on this. This study aimed to determine the AL rate for different types of colon cancer resection to inform decisions regarding the choice of operation.MethodologyRetrospective analysis of Bowel Cancer Outcome Registry (BCOR) for all colonic cancer resections with anastomosis between January 2007 and December 2020. Demographic, patient, tumour and outcome data were analysed. AL rates were compared among the different colonic procedures with both univariate and multivariate analysis.Results20 191 patients who underwent resection with anastomosis for cancer were included in this study. Of these 535 (2.6%) suffered ALs. While the univariate analysis found male sex, procedure type, symptomatic cancers, emergency surgery, unsupervised registrars, conversion to open surgery, medical complications and higher TNM staging were associated with AL, multivariate analysis, found only procedure type remained a significant predictor of AL (total colectomy (OR 4.049, P<0.001), subtotal colectomy (OR 2.477, P<0.001) and extended right hemicolectomy (OR 2.171, P < 0.001)).ConclusionAL is more common in extended colonic resections. With growing evidence of similar oncological outcomes between subtotal colectomy and left hemicolectomy for splenic flexure cancers, more limited resections should be considered. The type of colonic resection should be integrated into prediction tools for AL.
Scoping review showed that obesity prevention in Nordic countries had limited effects on children from birth to 7 years of age
Authors: Starnberg Josefine , Renström Lina 
Published: November 2023

AbstractAimThe aim of this scoping review was to map and summarise clinical trials that attempted to prevent obesity in children from birth to 7 years of age in any of the Nordic countries.MethodsPubMed, CINAHL Plus and clinicaltrials.gov were searched for peer‐reviewed papers and registered trials published in English or Swedish. The overall search period was from 1 January 2002 to 13 December 2022. We included randomised and non‐randomised trials initiated from birth to 7 years of age that aimed to prevent obesity in Denmark, Finland, Iceland, Norway and Sweden.ResultsThe search resulted in 414 papers and 14 were included. Despite having diverse settings and designs, none of them reported consistently favourable results for anthropometric outcomes, apart from beneficial trends in subgroups with a high body mass index at baseline. Most studies reported temporarily improved dietary patterns.ConclusionThere is a gap in the current research about how to best prevent obesity in children. We suggest that researchers should focus on risk groups and that interventions that last a number of years are needed.
Assessing and further developing age‐appropriate information for young people about reporting suspected adverse drug reactions
Authors: Bioletti Louis ,   Alder Hey Research Ambassadors, Woodward Charlotte , Jadeja Mitul , Hawcutt Daniel B. 
Published: November 2023

AimsThe Medicines and Healthcare products Regulatory Agency Yellow Card scheme (YCS) is the UK's system that collects spontaneous reports about suspected adverse drug reactions (ADRs). Reporting of suspected ADRs by young people (age <19 years) in the UK is extremely uncommon, driving efforts to improve awareness and reporting.MethodsQuality improvement project, using an anonymous online survey about updated information for young people, distributed through school pupils (age 13–18 years) across the UK through the Alder Hey Research Ambassador programme.ResultsResearch Ambassadors were recruited in 21 schools and colleges, generating 2933 responses (15 November 2022–08 April 2023); 6.3% of respondents had heard of the YCS, and 0.8% had previously reported a Yellow Card. There were 307 suspected drug–event combinations reported, 36 of which required attendance at hospital. The updated YCS reporting guide was understood by 92.8% of young people, and 90.8% reported knowing more about ADRs after reading the guide. The percentage of young people ‘Not comfortable’ reporting a suspected ADR decreased from 13.3% (before reading) to 4.1% after reading (P < .000001), and 84.5% of young people reported willingness to report a side effect in the future. The most common comments regarding further improvement of the information were content, or length of the text could be altered in some way (n = 543, 26.1%) and graphic design could be improved (n = 357, 17.2%).ConclusionsThe age‐appropriate information provided met many of their needs, increasing willingness to report. Integration into existing education curricula in the UK would facilitate knowledge transfer and improve reporting.
How our ideological out‐group shapes our emotional response to our shared socio‐political reality
Authors: Elad‐Strenger Julia , Goldenberg Amit , Saguy Tamar , Halperin Eran 
Published: November 2023

AbstractWhat shapes our emotional responses to socio‐political events? Following the social identity approach, we suggest that individuals adjust their emotional responses to socio‐political stimuli based on their ideological out‐group's responses, in a manner that preserves the comparative and normative fit of ideological in‐group–out‐group categories. In Study 1 and Study 2 (pre‐registered), Jewish‐Israeli leftists and rightists were exposed to their ideological out‐group's alleged emotional response to a stimulus associated with Israeli‐Palestinian relations, which was either stereotypical (leftists expressing low anger and rightists expressing high anger) or non‐stereotypical (leftists expressing high anger and rightists expressing low anger). Across studies, participants reported more positive affect towards their ideological out‐group when its response to the stimulus was non‐stereotypical versus stereotypical, yet their own response to the stimulus became more “extreme” (towards the low end of the anger scale for leftists, and towards the high end of the anger scale for rightists), shifting farther away from their ideological out‐group norm. Our findings suggest that in highly polarized contexts, where “leftist” and “rightist” identities are largely defined in comparison to one another, the “positioning” of ideological groups relative to one another plays a role in shaping their responses to their shared socio‐political reality.
Intratumor APOL3 delineates a distinctive immunogenic ferroptosis subset with prognosis prediction in colorectal cancer
Authors: Lv Yang , Zheng Peng , Mao Yihao , Xu Yuqiu , Chang Wenju , Lin Qi , Ji Meiling , Ye Lechi , Tang Wentao , Xu Jianmin 
Published: November 2023

AbstractWith the essential role of lipid transporting signaling in cancer‐related immunity, apolipoprotein L3 (APOL3), a member of the apolipoprotein L gene family, demonstrated significant modulation ability in immunity. However, the expression profile and critical role of APOL3 in colorectal cancer (CRC) remain unclear. This study aimed to investigate the prognostic significance of APOL3 expression and its biological predictive value in CRC. The study enrolled multiple cohorts, consisting of 911 tumor microarray specimens of CRC patients from Zhongshan Hospital, 412 transcriptional data from The Cancer Genome Atlas, and 30 single‐cell RNA sequencing (scRNA‐seq) from internal and external CRC patients. APOL3 mRNA expression was directly acquired from public datasets, and APOL3 protein expression was detected using immunohistochemistry. Finally, the associations of APOL3 expression with clinical outcomes, immune context, and genomic and ferroptotic features were analyzed. Low APOL3 expression predicted poor prognosis and inferior responsiveness to 5‐fluorouracil‐based adjuvant chemotherapy (ACT) and targeted therapy. APOL3 fosters an immune‐active microenvironment characterized by the promotion of ferroptosis, downregulation of macrophages, and upregulation of CD8+ T cell infiltration. Moreover, the expression of APOL3 in CD8+ T cells is intrinsically linked to ferroptosis and immune activation in CRC. In summary, APOL3 serves as an independent prognosticator and predictive biomarker for immunogenic ferroptosis, ACT, and targeted therapy in CRC. Furthermore, the APOL3 signaling activator could be a novel agent alone or in combination with current therapeutic strategies for CRC.