bluuebunny/crossref_metadata_2025_split huggingface dataset:
Implementation and evaluation of participatory advisory boards in mental health research: a research protocol of the ‘PART-Beirat’ project
Authors: Ferra Fenia , Drewelow Eva , Klein Olga , Daum Marcel , Walde Peggy , Gerullis Kai , Kilimann Ingo , Tomlin Jack , Teipel Stefan , Völlm Birgit 
Published: December 2023

Abstract
Background
The use of participatory research approaches in the field of dementia and forensic mental health research has been on the rise. Advisory board structures, involving people with lived experience (PWLE), have frequently been used for guiding and leading research. Yet, there has been limited guidance on the establishment, retention and use of advisory boards in the field of dementia and forensic mental health research.

Objective
This project outlined in this research protocol will investigate the benefits and challenges of establishing three patient advisory boards, involving PWLE, practitioners and researchers with the purpose to guide research. Data will be used to develop guidelines for best practice in involving PWLE in dementia and forensic mental health research through advisory boards.

Methods
The research project will be divided into three phases: Phase I will involve two topic-specific systematic reviews on the use of participatory research with PWLE, followed by an initial study exploring PWLE’s, practitioners’ and researchers’ expectations on research involvement. Phase II will consist of the establishment of three advisory boards, one focusing on dementia, one on forensic mental health and one overarching coordinating advisory board, which will involve PWLE from both fields. Phase III, will consist of interviews and focus groups with advisory board members, exploring any challenges and benefits of involving PWLE and practitioners in advisory boards for guiding research. To capture the impact of involving PWLE in different research phases and tasks, interviews and focus groups will be conducted at four different points of time (0, 6, 12, 18 months). Reflexive thematic analysis will be used for the analysis of data.

Discussion
The project aims to explore the involvement of PWLE and practitioners in guiding research and aims to develop guidelines for best practice in establishing and using patient advisory boards in dementia and forensic mental health research and involving PWLE and practitioners in research.
Breaking barriers: Exploring the Full Cup Test (FCT) pain scale at a tertiary care hospital
Authors: Ghouri Nida , Mushtaq Maria 
Published: December 2023

Background and Objective: Pain assessment plays a vital role in the management of patients across various healthcare settings. Accurate and reliable pain evaluation tools are essential for effective pain management and improving patient outcomes. The objective of this study was to assess ease of Full Cup Test (FCT) as a pain scale and to compare use of FCT with Visual Analogue Scale (VAS) for pain evaluation.
Methods: A cross-sectional study carried out at a tertiary care hospital from December 2021 to July 2022 on individuals with pain at various body locations. Pain severity was evaluated using two pain assessment tools, the FCT and the VAS. The main objectives of the study were to assess correlation and agreement between the FCT and VAS; using Kappa statistics.
Results: Of the total 288 subjects, median age was 42.5 years (IQR: 13-78), and median duration of pain was four months (IQR: one day to forty years). Analysis revealed significant positive correlation (r=0.577) between the Full Cup Test (FCT) and the Visual Analog Scale (VAS), indicating a relationship between both pain assessment tools. Significant agreement was also observed between FCT and VAS, with a kappa value of 0.596 (p<0.0001). Results however indicated that illiterate patients found it easier to understand FCT compared to VAS.
Conclusion: The Full Cup Test (FCT) emerged as a potentially valuable tool for assessing pain severity in a diverse range of patients. Regardless of age, gender, education level, and ethnicity, FCT demonstrated utility with ease in detecting pain severity.
doi: https://doi.org/10.12669/pjms.40.2(ICON).8944
How to cite this: Ghouri N, Mushtaq M. Breaking barriers: Exploring the Full Cup Test (FCT) pain scale at a tertiary care hospital. Pak J Med Sci. 2024;40(2):S35-S41. doi: https://doi.org/10.12669/pjms.40.2(ICON).8944
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Diabetes and its associated factors: A Retrospective cohort analysis of a large database at Indus Hospital Health Network
Authors: Amin Faridah , Imran Muhammad , Hafeez Syed Asif , Zehra Beenish 
Published: December 2023

Objectives: This is a retrospective cohort analysis of diabetes and its associated factors from Electronic Medical Record (EMR) of 2020-2022 of Indus Hospital Health Network (IHHN), Korangi campus Karachi.
Methods: Retrospective cohort study was conducted at Indus Hospital & Health Network (IHHN), Korangi Karachi. Out-patient records of adult patients of 2020-2022 were extracted from EMR of IHHN in March 2023. Descriptive statistics were presented as median (IQR) and frequency and percentage. Chi-square test determined association of risk-factors with diabetes and Wilcoxon-sign-rank test compared change in HbA1C from baseline.
Results: Data of 460,799 adult patients were extracted and analyzed. Median age of patients was 38.71 (27.87-52) years. Female preponderance was observed in our study. Out of 460,799, HbA1C was seen in 42,638 (9.25%) patients. Among these 29,596 (69.4%) had a HbA1C ≥ 6.5% while 13,042 (30.6%) had a HbA1C in the pre-diabetes range. Significant association was found between age, baseline creatinine, LDL and diabetes with no association depicted between gender, BMI, blood pressure, triglycerides, HDL and diabetes status. Patients in general had higher HbA1C at baseline as compared to last visit (p-value<0.001).
Conclusion: High blood pressure, obesity, increased creatinine, micro albuminurea, high LDL and Triglycerides were important risk factors for diabetes. This study reports a snap shot of the status of diabetes and associated risk-factors in the Pakistani population. This was the first time that a large data was extracted and analyzed from a healthcare institution in Pakistan, which would guide physicians and public health practitioners to take evidence-based decisions for prevention and management of diabetes.
doi: https://doi.org/10.12669/pjms.40.2(ICON).8948
How to cite this: Amin F, Imran M, Hafeez SA, Zehra B. Diabetes and its associated factors: A Retrospective cohort analysis of a large database at Indus Hospital Health Network. Pak J Med Sci. 2024;40(2):S10-S14. doi: https://doi.org/10.12669/pjms.40.2(ICON).8948
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The clinical manifestations and pregnancy outcomes of COVID-19 infection at a tertiary care hospital
Authors: Wali Aisha Syed , Ali Maria Mushtaq , Bibi Rabia , Rahim Anum 
Published: December 2023

Objective: To evaluate clinical presentation and pregnancy outcomes in pregnant women with Covid-19 infection in our local tertiary care from lower middle-income country.
Methods: A retrospective study was conducted at Obstetrics & Gynecology department, Sheikh Saeed Memorial Hospital (SSMH) of The Indus Hospital and Health Network (IHHN) from March 2020 to August 2021. Data of 422 admitted pregnant women with COVID-19 infection was retrieved for demographic and clinical information, laboratory tests, pregnancy outcome, and neonatal outcomes on RED-Cap and analyzed on SPSS 26. Univariate and multivariable logistic regression analyses were performed to estimate odds ratios (OR) for symptomology with categorical variables and feto-maternal outcome.
Results: Of the total 422 pregnant women, 24.4% were symptomatic, 74.7% exhibiting mild symptoms. Largely reported symptoms were fever (71.8%), cough (36.9%) and body ache (35.0%); while odds of symptomatic COVID-19 infection was less in educated pregnant women (OR 0.3; 95% CI 0.1-0.9) compared to uneducated. Amongst maternal comorbidities, odds of having symptomatic COVID-19 infection were 3.8 times (95% CI 1.1-13.0) in women with chronic hypertension and 5.5 times (95% CI 2.9-10.4) in women with diabetes. Symptomatic women had significantly greater incidence of miscarriages (p= 0.009), PPROM (p= 0.001), preterm birth (p= 0.000), preeclampsia (p= 0.000), placental abruption (p= 0.006) and maternal ICU admission (p= 0.000) than asymptomatic patients. Still birth was higher (6.4% vs 1.3%, p-value= 0.013) in symptomatic group. The odds of having severe maternal outcome were higher (OR=3.5; 95% CI 1.9-6.0) in symptomatic pregnant women.
Conclusion: Majority of pregnant women were asymptomatic. Symptomatic women with COVID-19 infection had an increased risk of adverse feto-maternal outcome.
doi: https://doi.org/10.12669/pjms.40.2(ICON).8949
How to cite this: Wali AS, Ali MM, Bibi R, Rahim A. The clinical manifestations and pregnancy outcomes of COVID-19 infection at a tertiary care hospital. Pak J Med Sci. 2024;40(2):S15-S20. doi: https://doi.org/10.12669/pjms.40.2(ICON).8949
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
The Impact of Family-Based Human Capital on Corporate Innovation: Evidence from Sibling-Chairpersons in China
Authors: Xu Nianhang , Chan Kam C. , Xie Rongrong , Chen Qinyuan , Agarwal Sumit 
Published: December 2023

We examine the impact of family-based human capital stemming from a chairperson’s having siblings vis-à-vis not having siblings on corporate innovation in Chinese family firms. Using hand-collected data, we document that when a firm has a sibling-chairperson, it holds more patents, receives more total citations to its patents, and has greater innovation efficiency and innovation quality than an otherwise equivalent firm with a chairperson having no siblings. The results are economically significant and robust to a battery of robustness checks. Specifically, the findings remain intact after using China’s one-child policy as an exogenous shock to apply a regression discontinuity research design to mitigate endogeneity. Additional analyses suggest that the mechanisms behind the impact of siblings on innovation are consistent with family-based human capital embedded in the sibling relationships such as competition, knowledge spillover, and family firm succession effect among siblings. Furthermore, we show that sibling comanagement and sibling gender diversity matter in corporate innovation. In addition, sibling effect enhances corporate investment efficiency, stock returns, and merger and acquisition performance. Overall, family-based human capital from siblings positively contributes to corporate innovation. This paper was accepted by Victoria Ivashina, finance. Funding: The authors acknowledge financial support from the National Natural Science Foundation of China [Grants 72225005 and 72202249] and the China Postdoctoral Science Foundation [Grant 2022M713658]. Supplemental Material: Data are available at https://doi.org/10.1287/mnsc.2023.4965 .
Private vs. Pooled Transportation: Customer Preference and Design of Green Transport Policy
Authors: Arora Kashish , Zheng Fanyin , Girotra Karan 
Published: December 2023

Problem definition: Large cities around the globe are facing an alarming growth in traffic congestion and greenhouse gas emissions, to which a significant contributor in recent years are on-demand cabs operated by ride-hailing platforms. Newly emerged pooled transportation options like shuttle services are cheaper and greener alternatives. However, those alternatives are still new to many customers and policy makers. The design of their promotion policies demands careful investigation. This paper studies how we can reduce the number of on-demand cabs on the road and, therefore, their GHG emissions by promoting pooled transportation such as shuttle services. Methodology/Results: In this work, we use detailed usage data and build a structural model to study customer preferences of price and service features when choosing between private cabs and a scheduled shuttle service. Using the estimated model, we identify and evaluate the efficacy of improving service features like reducing the walking distance to shuttle stops on customers’ choices of transport and, therefore, the number of ride-hailing vehicles on the road. We find that a 20% decrease in walking distance can achieve 40% of the benefits of commonly adopted congestion surcharge policies. It can also reduce up to 4.8 thousand tonnes of GHG emissions, which is worth over a million dollars per year. In addition, we demonstrate the implementability of walking distance reduction policies by adding stops on existing shuttle routes. Managerial implications: Reducing the number of ride-hailing vehicles on the road has become an important goal in many cities’ green transport policy design. For example, cities like New York have implemented congestion surcharge policies targeting ride-hailing vehicles in recent years. Our findings suggest that, by changing operations levers such as service features of pooled transport, cities can achieve a substantial amount of benefits from reducing congestion compared with congestion surcharge policies with essentially zero cost, leading to much more efficient green transport policies. Supplemental Material: The online appendix is available at https://doi.org/10.1287/msom.2022.0569 .
Traditions of Folk Medicine in Georgia and Perspectives of Using Natural Medicinal Plants
Authors: Elizbarashvili Nodar , Gurgenidze Miranda , Elizbarashvili Rusudan , Bubashvili Luiza 
Published: December 2023

The treatment methods and knowledge accumulated in Georgia over the centuries are related to the country's geographical location, diverse nature, traditions, history and knowledge of the use of medicinal products.
The article discusses a brief history of the development of folk medicine in Georgia, the medicinal plants that have been used in traditional medicine for centuries, the biological and landscape diversity of the country, the geographical features of the distribution of some medicinal plants and their main medicinal purpose, the economic importance of medicinal plants and the problems associated with their extraction.
Pharmaceutical Care for Premature Infants with Candida Albicans Infection of the Central Nervous System
Authors: Zheng Zi-Qiang , Yang Chao-Wen , Liu Hong-Xia 
Published: December 2023

Objective: To explore the role of clinical pharmacists in the treatment of clinical diseases by adjusting the treatment of Candida albicans infection in the central nervous system of a premature infant.
Methods: Clinical pharmacists participated in the treatment of one premature infant with Candida albicans infection of the central nervous system, and provided drug selection suggestions based on drug safety and pharmacokinetics.
Results: The doctor partially adopted the suggestions of clinical pharmacists, revised the medication plan, and the child received reasonable treatment.
Conclusion: Clinical pharmacists can make full use of pharmaceutical knowledge to serve the clinic and improve the level of rational drug use.
SELAHATTİN ENİS’İN ROMANLARINDA ENGELLİLER VE ENGELLİLİK
Authors: GÜLER Aydın 
Published: December 2023

1892-1942 yılları arasında yaşamış olan Selahattin Enis Atabeyoğlu, genç yaşlarda başladığı edebî hayatına sekiz roman ve bir hikâye kitabı sığdırmıştır. Bunların yanı sıra Piyano, Resimli Kitap, Keşkeşan, Rübab, Kaplan gibi pek çok dergide yazılarını ve hikâyelerini yayımlamıştır.
Bu çalışmada Selahattin Enis’in romanları incelenerek engelliliğin romanlardaki görünümü ve engelli karakterlerin romanlardaki rolü değerlendirilmiştir. Bu çalışmanın yapılması için Selahattin Enis’in Neriman, Sara, Zaniyeler, Cehennem Yolcuları, Orta Malı, Ayarı Bozuklar, Endam Aynası ve Mahalle adlı romanları içerik analizi yöntemiyle okunmuş, engelli karakterler tespit edilerek adı geçen romanlarda kurguya katkıları vurgulanmıştır.
Zaniyeler, Cehennem Yolcuları, Orta Malı, Ayarı Bozuklar ve Mahalle romanlarında engelli karakterler tespit edilmiştir. Ancak Selahattin Enis, her romanda engelli karakterlerine farklı tarz ve yoğunluklarda yer vermiştir.
Hemophagocytic lymphohistiocytosis with jaundice as first manifestation: A case report
Authors: Wang Dan-Dan , Wu Sheng , Kong Bing-Bing , Song Lin-Lin 
Published: December 2023

BACKGROUND
Hemophagocytic lymphohistiocytosis (HLH) is a rare but life-threatening condition. It is an immune-mediated disease that has a wide range of causes, elicits a hyperinflammatory response, and results in multiple organ damage. Clinical presentations vary, and in some cases, jaundice occurs as the first symptom.
CASE SUMMARY
We report the case of a 71-year-old female patient who presented with jaundice. She was admitted to our hospital because of the occurrence of “jaundice for half a month”, and upon examination, obstructive jaundice with choledocholithiasis and gallstones was suggested. Cholecystectomy and choledocholithotomy were performed. However, the jaundice did not improve after surgery. We found splenomegaly, cytopenia, hypertriglyceridemia, hypofibrinogenemia, and elevated ferritin. Bone marrow biopsy revealed hemophagocytosis. Later, cardiac arrest occurred when she returned 3 wk after the surgery. We considered that HLH was triggered by septic shock. The patient’s condition deteriorated rapidly, with multiple organ dysfunction and severe gastrointestinal bleeding. Corticosteroid therapy and symptomatic treatment failed to save her life.
CONCLUSION
Jaundice rarely presents as the first symptom in HLH patients. The HLH in this case was triggered by septic shock with jaundice as the first symptom. Clinicians should try hard to reduce missed diagnoses and misdiagnoses.
Design and Evaluation of a Shear Analogy Tool for Custom Cross-Laminated Timber (CLT) Panels Made from Various Wood Species
Authors: Adhikari Sailesh , Quesada Henry , Bond Brian 
Published: December 2023

Abstract
A user-friendly cross-laminated timber (CLT) design tool called SAM-CLT was developed to calculate the minimum design values for custom CLT panels. Custom panels are those made from different species not currently included in APA PRG 320 and include the use of multiple species in a panel. The tool uses the design value of hardwood and softwood lumber published in the national design specification book to design custom CLTs and the standard CLT grade lumber specification values published in PRG 320 standard. SAM-CLT was designed based on the shear analogy model and is intended to assist CLT manufacturers, construction and design companies, and researchers in designing and evaluating CLTs’ deformation when using different lumber types and thicknesses. This project included the calibration and validation of the tool, followed by examples of its use by computing the design value of the softwood, hardwood, and softwood–hardwood hybrid CLTs. The SAM-CLT tool was adjusted to match the published standard design values on PRG 320 and validated by comparing output for standard CLT layups. In the next step, SAM-CLT tool was used to calculate the minimum design value of custom CLTs made from hardwood–yellow poplar lumber and softwood–southern yellow pine lumber. Based on observed validation results of the tool and its application results to determine the design values for various CLT layups, this project concludes that SAM-CLT can be a valuable tool for designing custom CLTs, evaluating CLTs’ strength properties, and promoting heterogeneous lumber types in CLT manufacturing.
I Logotechnia sto Panepistimio: I Sygkrotisi tis Epistimis tis Neoellinikis Filologias (1942–1982) (‘Literature at the University: The Formation of the Scholarly Study of Modern Greek Literature [1942–1982]’), Venetia Apostolidou (2022)
Authors: Papatheodorou Yiannis 
Published: December 2023

Review of: I Logotechnia Sto Panepistimio: I Sygkrotisi Tis Epistimis Tis Neoellinikis Filologias (1942–1982) (‘Literature at the University: The Formation of the Scholarly Study of Modern Greek Literature [1942–1982]’), Venetia Apostolidou (2022)
Athens: Polis, 560 pp.,
ISBN 978-9-60435-785-7, p/bk, €27.70
Species diversity of the genus Allium in the flora of Aral-Balkhash region
Authors: Abdildanov D. Sh. , Vesselova P. V. , Kudabayeva G. M. 
Published: December 2023

Currently, the genus Allium L., which is one of the largest genera of the Monocotyledon class, has more than 1000 species in its composition. In the flora of Kazakhstan, the genus is represented by at least 130 species. The species of this genus are characterized by a variety of morphological characteristics, which makes it difficult to determine them. The ecological range of the species of the genus is also wide and extends from the alpine and subalpine belts to deserts. According to modern data, 25 (19 % of 130) alliums growing in Kazakhstan are found in the Aral-Balkhash region. The aim of the research was to study critically the diversity of species of the genus Allium from 3 sections (Haplostemon Boiss. -7; Porrum Don - 3, Molium Don - 5) of the flora of the Aral-Balkhash region. The conspectus presented in the article is based on the critical review of available herbarium materials: the Institute of Botany and Phytointroduction (AA), (Almaty, Kazakhstan), the digital herbarium of the Lomonosov Moscow State University (Moscow, Russia), the Herbarium (TASH) of the Institute of Botany of the Academy of Sciences of the Republic of Uzbekistan, taking into account the modern system of the genus Allium. For each species, information on the biological characteristics of the species, their ecological confinement and geographical distribution is provided. Screening of herbarium samples revealed 158 plant vouchers belonging to 15 species from 3 sections. The results of the analysis of the edaphic confinement of species, in general, confirm the validity of the distribution of species in the presented sections.
The representatives of the family Saxifragaceae in the collection «Alpine Slides» of the Peter the Great Botanical Garden of Komarov Botanical Institute of RAS
Authors: Baranova O. G. 
Published: December 2023

The article gives an assessment of the wealth of the collection fund of representatives of the family Saxifragaceae, growing in the modern period of time in the collection “Alpine Slides” of Peter the Great Botanical Garden and in earlier years. The purpose of the article is to evaluate the lifespan of individual specimens in the collection and to identify plant species that are most resistant to growth in the conditions of St. Petersburg. Currently, in the collection “Alpine Slides”, plants of the family Saxifragaceae are represented by 41 species from 10 genera. The genus Saxifraga is the most diverse in the collection, with 16 species, 10 of which have been added to the collection over the past 10 years. Most of the specimens of representatives of the family Saxifragaceae in the modern collection were obtained from Delectus seeds from Sweden, Poland, Germany and other countries. They were planted in the 20th century; a particularly large influx of species into the collection occurred in the 1950s-1960s. Many samples in the collection exist for more than 60-70 years, which indicates the prospects for the use of many representatives of the family Saxifragaceae in landscaping.