bluuebunny/crossref_metadata_2025_split huggingface dataset:
Relationship between Vascular Cell Adhesion Molecule-1 (Vcam-1) Level with Severity Degree of COVID-19 Patients at General Hospital H. Adam Malik Medan
Authors: Elvira  , Siregar Jelita , Lubis Inke Nadia Diniyanti , Herman Hariman  
Published: December 2023

Background: The mechanism and pathogenesis of COVID-19 that distinguishes asymptomatic, mild, moderate, severe to critical symptoms is not yet known with certainty. Endothelial dysfunction and immune thrombosis serve as a profound pathogenic mechanism in COVID-19. Vascular Cell Adhesion Molecule-1 (VCAM-1) is a major regulator of leukocyte adhesion that contributes to the formation of thrombosis. The purpose of the study determine the relationship between VCAM-1 level with the severity degree in COVID-19 patients.
Methods: An analytical study with a cross-sectional design was conducted from September – March 2022. This study was followed by 50 patients aged over 18 years with moderate, severe, and critical degrees of COVID-19 admitted to Haji Adam Malik General Hospital Medan by excluding malignancy and pregnancy patients. Serum VCAM-1 levels were measured using Chemwell Analyzer.
Results: Among 50 patients, 33 patients (66%) were male and 17 patients (34%) were female. The mean age was 57 years with the youngest 19 years old and the oldest 81 years old. The median level of VCAM-1 was 23,02 ng/mL (10.96 ng/mL - 50.63 ng/mL). The median concentration of VCAM-1 was 37.85 ng/mL (15,59 – 50.63), 36.68 ng/mL (19.58 – 49.71), and 18.83 ng/mL (10.96 – 46.32) for critical, severe, and moderate degree respectively (p = 0.001). The cut-off value of VCAM-1 levels to predict the severity of COVID-19 is 32.01 ng/mL.
Conclusions: There is a significant relationship between VCAM-1 levels and the severity of COVID-19.
Two Poems
Authors: Nguyen Hoa 
Published: December 2023

<p>Two Poems, <em>The Puritan</em>, Toronto, ON </p>
<p><em><strong>VIETNAMESE SUPERNATURALISM NOTES: DIVINE MOTHER</strong></em></p>
<p><em><strong>WHY THIS HAUNTED MIDDLE AND DOOR HUNG WITH HAUNTED GIRL BONES</strong></em></p>
Pembiasaan Shalat Dhuha Terhadap Sikap Spiritual Siswa di Pondok Pesantren MTS Plus Bahrul Ulum Islamic Centre Sungailiat Bangka
Authors: Mukarromah Dewi Hani 
Published: December 2023

Permasalahan ini diambil karena dilatarbelakangi oleh pendidikan yang saat ini banyak mendapat kritikan karena hanya mampu mencerdaskan peserta didik secara akal, namun kosong akan ruh. Disinilah pentingnya pemahaman tentang spiritual, yang mana jika seorang manusia paham akan pemahaman tentang kecerdasan spiritual yang sifatnya langsung aplikatif dengan tujuan untuk mengembangkan sikap spiritual peserta didik, maka ia akan dapat menyeimbangkan antara urusan duniawi dengan urusan akhirat. Sosok seorang guru sangat berperan penting dalam mengembangkan sikap spiritual anak, yang mana guru dapat menjadi contoh/teladan yang baik bagi peserta didik. Dari apa yang dilakukan oleh para guru di Pondok Pesantren MTs Plus Bahrul Ulum Islamic Centre Sungailiat setidaknya sudah menggambarkan hal tersebut.
Dalam penelitian ini metode yang digunakan adalah pendekatan kualitatif, dengan
jenis penelitian lapangan, yaitu prosedur penelitian yang menghasilkan data deskriptif berupa kata-kata tertulis atau lisan dari orang-orang dan perilaku yang dapat diamati. Pengumpulan data utamanya dilakukan dengan wawancara secara terstruktur, dan diperkuat dengan pengamatan partisipatif pasif, serta studi dokumentasi dengan menelaah buku-buku dan menelusuri dokumen-dokumen atau arsip sekolah yang relevan dengan masalah yang diteliti, selanjutnya data yang terkumpul kemudian dianalisis dengan menggunakan analisis deskriptif kualitatif. Adapun yang menjadi subjek penelitian ini adalah kepala sekolah, guru dan siswa.
Hasil penelitian menunjukkan, bahwa (1) Hasil pelaksanaan pembiasaan shalat dhuha
dalam mengembangkan sikap spiritual siswa di Pondok Pesantren MTs Plus Bahrul Ulum Islamic Centre Sungailiat berjalan dengan lancar. Hal ini ditandai dengan pelaksanaannya sampai sekarang masih terus dilakukan. Kemudian pembiasaan shalat dhuha dalam mengembangkan sikap spiritual siswa dapat dikatakan cukup baik, hal ini ditandai dengan perubahan perilaku positif, perkembangan itu dapat dilihat: pertama, siswa yang mengikuti pembiasaan shalat dhuha bisa memanfaatkan waktu di pagi hari dengan produktif. (2) Tingkah lakunya mengarah pada hal yang baik sesuai dengan ajaran Islam, yaitu ikhlas, sabar, syukur, dan tawakkal. Dan guru pun berupaya keras agar siswa yang mereka didik bisa mencerminkan sikap spiritual tersebut.
Peran Guru Pendidikan Agama Islam dalam Membentuk Karakter Peduli Lingkungan di SDN 7 Lubuk Besar
Authors: Mu'minah Ummul 
Published: December 2023

Diambilnya permasalahan ini berdasarkan pertimbangan bahwa saat ini mutlak dibutuhkan alternatif-alternatif yang praksis dalam pengejawantahan karakter peduli lingkungan. Dari apa yang dilakukan oleh guru Pendidikan Agama Islam setidaknya menggambarkan hal tersebut bahwa seiring perkembangan zaman, karakter peduli lingkungan harus terus ditanamkan pada umat, terutama pada peserta didik sekolah dasar (SD) sebagai langkah awal pemebentukan karakter anak bangsa.
Penelitian ini merupakan hasil kajian dan pengamatan terhadap pembentukan karakter peduli lingkungan melalui peran guru Pendidikan Agama Islam di SDN 7
Lubuk Besar. Pengumpulan data utamanya dilakukan melalui wawancara mendalam kepada guru Pendidikan Agama Islam dan diperkuat dengan observasi serta dokumentasi berupa data umum SDN 7 Lubuk Besar dan gambar-gambar kondisi lingkungan di SDN 7 Lubuk Besar. Selanjutnya, data yang terkumpul kemudian dibenturkan dengan teori-teori yang relevan agar didapat gambaran komprehensif atas kondisi obyektif.
Hasil penelitian menunjukkan bahwa peran guru Pendidikan Agama Islam dalam
membentuk karakter peduli lingkungan di SDN 7 Lubuk Besar ternyata mampu menjadi salah satu solusi alternatif dalam membentuk dan mengembangakan karakter peduli lingkungan peserta didik, khususnya pada peserta didik sekolah dasar (SD).
Hubungan Gaya Belajar Siswa Terhadap Hasil Belajar Pendidikan Agama Islam di SMPN 3 Air Gegas
Authors: Yuselia Yuselia 
Published: December 2023

Inti dari proses pendidikan adalah belajar dan pembelajaran. Belajar adalahsuatu kegiatan untuk mencapai perubahan perilaku. Sedangkan pembelajaran adalah proses interaksi. Pendidikan dan pembelajaran ini dapat diberikan sejak ia masih kecil hingga tumbuh menjadi dewasa. Setiap mereka akan berkembang sesuai dengan pengalaman yang diberikan kepadanya. Cara belajar merupakan kombinasi dari keunikan kita dalam menyerap, mengatur, dan mengolah informasi. Dengan mengetahui cara dalam belajar, maka akan terasa mudah dalam menerima informasi dan bisa diserap sesuai pemahaman yang diberikan. Hal ini merupakan kemampuan yang kita miliki dalam belajar. Setiap anak memiliki lebih dari satu gaya belajar yang dipakai dalam usaha mencapai tujuan belajarnya. Apabila guru dapat menemukan kecenderungan gaya belajar siswa, maka hal ini akan bermanfaat sekali dalam mengembangkan proses belajar mengajar mereka. Setiap orang yang melakuakan proses belajar, maka akan terlihat hasilnya.Penelitian ini adalah penelitian yang kuantitatif. Teknik pengumpulan datanya menggunakan angket yang disebarkan kepada siswa kelas 7, 8, dan 9 dengan sampel sebanyak 79 siswa, kemudian analisis data menggunakan SPSS versi 26 dengan teknik analisis korelasi bivariat pearson. Hasil penelitian ini 1) gaya belajar siswa di SMP N 3 Air Gegas termasuk dalam kategori cukup baik, 2) hasil belajar pendidikan agama Islam di SMPN 3 Air Gegas termasuk dalam kategori sangat baik, 3) hasil uji korelasi yaitu terdapat hubungan yang signifikan antara gaya belajar siswa terhadap hasil belajar pendidikan agama Islam di SMP N 3 Air Gegas. Besar koefisien korelasi antara gaya belajar siswa terhadap hasil belajar pendidikan gama Islam sebesar 0,320. Nilai signifikansi hubungan antara kedua variabel ini adalah 0,004. Dengan demikian 0,004<0,05 terdapat hubungan yang signifikan antara gaya belajar siswa terhadap hasil belajar Pendidikan agama Islam.
Optimasi Konsentrasi Primer Dan Suhu Annealing Dalam Mendeteksi Gen Blaz Pada Bakteri Methicillin Resistant Staphylococcus Aureus Di Udara
Authors: Mardiana Anisah , Dhanti Kurnia Ritma , Kurniawan Kurniawan , Sulistyowati Retno 
Published: December 2023

Staphylococcus aureus is a species of bacteria that is often identified as a source of infection and has increased the number of cases of resistance. Resistance to Penicillin-class antibiotics in S. aureus is associated with plasmids containing the blah-Z gene encoding ß-Lactamase. Some factors that can be modified to obtain optimal test results in PCR are annealing temperature and primary concentration. This study aims to identify the primary concentration and annealing temperature that produce PCR products with the best band in detecting the blaZ gene in Metichilin Resistant Staphylococcus aureus (MRSA) bacteria. The research design used used experimental methods. The results of the study obtained were PCR products at primary concentrations of 10 μM were clearly visible, thick and clean, compared to primary concentrations of 5 μM. Annealing temperature with the best band results at temperatures of 61.8 °C and 58.7°C. This study concluded the primary concentration to obtain a clearly visible band result of 10 μM. The annealing temperature of 61.8°C produced the best band in the sample code R.PG. U4, R.V.U2, and R.151.U2 temperatures. While the sample code R.IGD. U5 band results best at annealing temperature 58.7°C.
Pengaruh Rebusan Akar Saluang Belum (Lavanga sarmentosa) Terhadap Jumlah Spermatid pada Gambaran Histologis Tubulus Seminiferus Mencit
Authors: Permatasari Silvani , Rahmatina Hairunnida , Widayati Ratna , Eka A I Gde 
Published: December 2023

The Dayak tribe of Kalimantan is known as the root of Saluang Belum (Lavanga sarmentosa) a traditional medicinal plant that has properties to increase stamina, and sexual arousal and is used as an alternative medicine to increase male fertility. L.sarmentosa is consumed by drinking the boiled water of the plant's roots. The aim of this study is to determine the effect infusion roots of Saluang Belum (L.sarmentosa) in increasing the spermatids as seen in the tubulus seminiferus histological of mice (Mus musculus). The root will be extracted by the infusion method with different doses for each group, namely 200 mg/KgBB, 400 mg/KgBB, and 600 mg/KgBB, and negative controls (aquades) which was carried out for 15 days to mice. On the day 16, the right testis was taken and histological preparations were made with hematoxylin-eosin staining and observed under a microscope at 400x magnification in five fields of view. Compounds contained in the infusion of L.sarmentosa are alkaloids, saponins, triterpenoids, flavonoids, phenolics, and steroids. The number of spermatids in the tubulus seminiferus histological of mice increased statistically significantly from the doses of 200 mg/KgBB, 400 mg/KgBB, and 600 mg/KBBg. Conclusion: Infusion of the roots L.sarmentosa can increase the number of spermatids seen in the tubulus seminiferus histological of mice.
Study Komparasi Penambahan Palm Oil Ash Dengan Bantuan Semen Berdasarkan Nilai California Bearing Ratio
Authors: Saputra Norseta Ajie , Handayani Noviyanthy , Santoso Benny 
Published: December 2023

High water content, water saturation, and low carrying capacity are characteristics of clay soils. The road body may have an uneven surface. On the other hand, in the dry season it will harden and have a high carrying capacity so that a lot of dust is scattered on the road and blocks the driver's view. As a result, the neighborhood can experience traffic jams and accidents. Check the CBR and PI values to see if there is an increase in clay after stabilization using a mixture of Palm Oil Fuel Ash and cement with variations (0% POFA + 2% Cement), (3% POFA + 2% Cement), (5% POFA + 2% Cement), and (7% POFA + 2% Cement). Test method Sieve Analysis, Atterberg Limit, Specific Gravity, Moisture Content, Compaction and CBR. Cement and palm oil bunch ash produced a CBR value of 7.4% compared to a natural soil CBR value of 1.59%. The CBR value of the soil will increase, the dry unit weight value will decrease, and the plasticity value will decrease with the higher proportion of Oil Palm Bunch Ash and cement
Pengaruh Penggunaan Media Video Terhadap Hasil Belajar Pada Materi Sistem Pencernaan Manusia di Kelas XI IPA B SMA Immanuel Sintang
Authors: Marzuki Marzuki 
Published: December 2023

Model pembelajaran Media Video merupakan salah satu media yang efektif untuk pembelajaran di dalam kelas, karena penyajian materi dapat dilihat secara nyata sehingga siswa lebih termotivasi untuk belajar. Tujuan penelitian yaitu untuk mengetahui pengaruh penggunaan media video terhadap hasil belajar pada materi sistem pencernaan makanan pada manusia di kelas XI IPA B SMA Immanuel Sintang. Metode penelitian ini menggunakan metode penelitian kuantitatif. Rancangan penelitian adalah Quasi Experimental Design. Teknik pengumpulan data yang digunakan dalam penelitian ini adalah teknik pengukuran dan observasi. Hasil penelitian berdasarkan analisis data diperoleh thitung dengan ttabel yaitu: 4,84 > 1,696 maka H0 ditolak dan H1 diterima. Berarti model pembelajaran media video berpengaruh terhadap hasil belajar siswa materi sistem pencernaan makanan pada manusia di kelas XI IPA SMA Immanuel Sintang, dan hasil perhitungan effect size besarnya pengaruh penggunaan media video terhadap hasil belajar pada materi sistem pencernaan pada manusia di kelas XI IPA B SMA Immanuel Sintang yaitu 0,32 dikategorikan kedalam kriteria kecil.
Cover, Content, and Editorial Note from Pengabdianmu J Pengabdian Masyarakat Vol. 8 No. 4 July 2023
Authors: PengabdianMu J Pengabdian Masyarakat Chief Editor of 
Published: December 2023

Assalamu’alaikum Wr. Wb.
Dear reader, now PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat re-published on Volume 8 Issue 4 July 2023. The publication of PengabdianMu: Jurnal Ilmiah Pengabdian kepada Masyarakat certainly participate in disseminating the results of community services in science and technology development conducted by lecturers and researchers especially from UMPR and other universities.
This edition contains 21 articles consisting of Education, Social and Political, Agriculture, and Health Science topics. Editorial boards are fully aware that there are still room for improvement in this edition, hence with all humility willing to accept constructive suggestions and feedback for improvements to the publication for the next editions.
The editorial board would like to thank the University, all editors and reviewers, and contributors of the scientific articles who have provided the repetoire in this issue. We hope that all parties, especially the contributors of the articles, could re-participate for the success of the publication in the next edition on September 2023.

Wassalamu’alaikum Wr. Wb.
Implementación de aula invertida (AI) a nivel de educación superior enfocado en el aprendizaje basado en proyectos
Authors: Montfort de Juliao Adriana , Retamozo Castillo Carlos Arturo , Ormelis Rodríguez Cornelia , Dixon Frias Eduardo Antonio , Champsaur Mojica Lisbeth 
Published: December 2023

En la educación superior, se hace necesario disponer de metodologías activas, donde los estudiantes consoliden su auto aprendizaje, logrando optimizar las habilidades metacognitivas al sustituir las clases magistrales y la exposición de contenidos sin promover la participación de los discentes. Se identifican los beneficios del AI con un enfoque individual y personalizado, respetando sus ritmos de aprendizaje e implementándolo a través del uso de tecnologías avanzadas y recursivas. Para su desarrollo, se escogieron dos asignaturas (Estática en un Plano y Publicidad Básica II) de la Facultad de Tecnología Construcción y Medio Ambiente para evaluar su trazabilidad, los docentes y estudiantes fueron capacitados en su metodología. El AI, no pretende ser rigurosa ante los cambios, sino que se ajusta en gran medida al proceso binomial de enseñanza aprendizaje, por lo que la exposición de videos fue esencial, siendo observados por los estudiantes en su momento individual (casa) para luego poder socializarlos ante la clase en el momento grupal, la función del docente fue un guía, dinamizando el aprendizaje con actividades grupales, teniendo el tiempo para consolidar y ampliar contenidos. Finalmente se evalúa no solo el conocimiento adquirido por los estudiantes al tomar un rol activo, como también al profesor en su papel de guía. Los resultados fueron sorprendentes, permitiéndonos determinar que AI es una gran oportunidad de aprendizaje y tiene efectos positivos en el logro de las habilidades metacognitivas, de acuerdo con la percepción recibida de parte de los grupos de estudiantes que participaron
Determination of Values of the Tricuspid Annular Plane Systolic Excursion (TAPSE) In Bangladeshi Adult Patient With or Without LV Dysfunction
Authors: Tamanna R J , Hoque S J , Pasha F M 
Published: December 2023

Background: Tricuspid annular plane systolic excursion (TAPSE) is an Echocardiographic measure that allows us to assess right ventricular systolic function and it correlates well with reference techniques like Cardiac Magnetic Resonance Imaging. TAPSE measurement is common in adults.
Objective: Our objective was to determine values of TAPSE in Bangladeshi adults with or without LV systolic dysfunction and to determine the relationship of these values with age, sex, RVIDd, LVEF & EPSS.
Method: This was an prospective observational study in patients undergoing comprehensive transthoracic echocardiography for any indication. From April 2022 to April 2023 we prospectively enrolled 100 adult (from 30 to age 80 years) of both sexes who presented to the Cardiology Clinic of LABAID Cardiac Hospital. We performed a complete transthoracic echocardiography study. We measured TAPSE in 2-dimensional M-mode echocardiograms from the apical 4- chamber view, positioning the cursor on the lateral tricuspid annulus near the free RV wall and aligning it as close as possible to the apex of the heart . The mean values were taken by at least 2 measurements for reducing interobserver and intraobserver variability’s. Patients with confirmed congenital & valvular heart disease were excluded.
Results: Mean TAPSE values were 19.15±3.87cm irrespective of LVEF, with no significant differences between sexes, 18.45±3.801 in male , 19.94±3.853 in female (P=.056). TAPSE value was 22.00±1.581 in person with normal LVEF & 16.77±2.455 in person with reduced LVEF ( P<.001) A statistically significant positive correlation of LVEF (r=.813) and significant negative correlation of EPSS (r=-.639) were observed with TAPSE (p<0.001). But no significant correlation of TAPSE was found between age (r=-.185)). ), gender (r=.192) & RVIDd (r= -.063) (p >0.05). Multivariate analysis confirmed these correlations and the interactions between variables (LVEF & EPSS). Graphs of estimated population-based TAPSE values adjusted by age and LV function are provided.
Conclusion: We determined values of TAPSE in Bangladeshi adult population with or without LV systolic dysfunction and assessed relationship of these values with age, sex, RVIDd, LVEF & EPSS. The TAPSE measurement was reproducible and associated directly with LV systolic function. These reference values could guide decision making in daily clinical practice.
Bangladesh Heart Journal 2023; 38(2): 92-101
Ultrasound Based Flow Measurements of the Left and Right Carotid System of Arteries in Bangladeshi Patients
Authors: Mamun Abdullah Al , Hosain Nazmul , Amin Farzana 
Published: December 2023

Carotid arteries are the major supply to the head, neck and brain. The right common carotid artery usually originates from the brachiocephalic artery while the left common carotid artery arises as a direct branch of the arch of the aorta. Common carotid arteries bifurcate at the level of the carotid sinus into the internal carotid artery, which supplies the brain, and the external carotid artery. Approximately 15–20% of the cardiac output is distributed to the brain in healthy adults under resting conditions. Cardiovascular diseases are the leading cause of death globally, taking an estimated 17.9 million lives each year. US 2017 statistics shows that cerebrovascular disease or Stroke alone ranked fifth for males but fourth for females. Ultrasonography can measure the velocity of blood flow in the Carotid system of arteries. A total 139 patients, who underwent Carotid Duplex study between July 2021 and June 2022 were included in this cross-sectional study. The criteria for exclusion included age less than 13 years, presence of associated peripheral vascular diseases, hemodynamically unstable patients, incomplete data collection and patient’s reluctance to join the study. Data analysis was performed using MS Office Excel. The Peak systolic velocity and the End diastolic velocity were measured at four levels, namely the Common carotid arteries and the Internal carotid arteries on the right and the left sides. No significant difference was observed in the Peak systolic velocity and the End diastolic velocity in either Common carotid or the internal carotid arteries between the right and left sides. Moreover, these findings were similar both in age groups above and below 50 years of age.
Bangladesh Heart Journal 2023; 38(2): 110-114
Selection and validation of genes related to oxidative stress production and clearance in macrophages infected with Mycobacterium tuberculosis
Authors: Su Renchun , Yuan Jinfeng , Gao Tianhui , Liu Yuhong , Shu Wei , Wang Yufeng , Pang Yu , Li Qi 
Published: December 2023

BackgroundIn the fight against tuberculosis, besides chemotherapy, the regulation of oxidative stress (OS) has also aroused people’s interest in host-oriented therapy. However, there is limited research on the genes involved in reactive oxygen species (ROS) production and clearance in macrophages infected with Mycobacterium tuberculosis (MTB). This study analyzes and explores this to provide a basis for exploring new targets for antituberculosis treatments.MethodsWe established a macrophage model infected with MTB, counted intracellular bacteria, and determined the ROS produced using flow cytometry. We conducted ribonucleic acid sequencing, screened differentially expressed genes through transcriptomic methods, and validated the expression of them through reverse transcription-quantitative polymerase chain reaction.ResultsThe ROS of macrophages increased with intracellular bacteria at 4 h after infection with MTB and reached its peak at 48 h, surpassing the uninfected macrophages (p &lt; 0.05). A total of 1,613 differentially expressed genes were identified after infection with MTB, of which 458 were associated with ROS, with over 50% involved in the response of organelles and biological processes to stimuli. We analyzed and identified six genes. After macrophage infection with MTB, the expression of CAMK2B increased, whereas the expression of CYBB decreased (p &lt; 0.05). The expression of GPX3 and SOD2 increased, whereas the expression of CAT decreased (p &lt; 0.05).ConclusionThe ROS-related differentially expressed genes between MTB infected and uninfected macrophages may be related to some organelles and involved in various biological processes, molecular functions, and signaling pathways. Among them, CAMK2B, GPX3, and SOD2 may be related to ROS.