bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of “weak B” phenotypes and their evaluation and differentiation in healthy blood donor population in Eastern India
Authors: Das Sudipta Sekhar , Mukherjee Sourav , Chowdhury Sourav 
Published: February 2024

Abstract

BACKGROUND:
Examples of group B red cells that react weakly or not at all with anti-B have been described. Subgroups of B such as B3, Bx, Bm, and Bel are rare and are less frequently reported. We studied the frequency of subgroups of B in our healthy blood donor population and serologically characterized and differentiated these subgroups.

MATERIALS AND METHODS:
The 9-year prospective study included 84,534 healthy blood donors. Initial blood grouping and antibody screening of all donor samples were performed using automated solid-phase assay. Any sample showing blood group discrepancy or weaker agglutination was subjected to further immunohematological investigations.

RESULTS:
Among 84,534 healthy donors, “B” blood group was found in 29,190 (34.53%). Weak B phenotypes were demonstrated in 9 (0.031%) B donors. Among the 9 weak B phenotypes, B3 was the most common followed by Bm. The frequency of B3, Bm, Bx, and Bel in our blood donor population was found to be 1 in 21,133, 1 in 28,178, 1 in 84,534, and 1 in 84,534, respectively. Red cell agglutination with anti-B and anti-AB varied from Wk+ to 2+ with or without mixed-field agglutination in the B3 and Bx phenotypes. Naturally occurring anti-B of immunoglobulin M type was detected in the Bx donor. Two (22.2%) of the 9 donors were found to be nonsecretor. Adsorption-elution demonstrated “B” antigen specificity in different strengths in Bm, Bx, and Bel phenotypes.

CONCLUSION:
We conclude that differentiating weak subgroups of “B” by serological assays is possible to a great extent with technical expertise. Mistyping weak subgroups of B as “O” group may lead to reporting errors and wrong blood transfusion. Therefore, blood centers in developing countries including India should establish simple techniques to detect and differentiate weak subgroups and develop procedures to ensure safe blood transfusion and transplantation.
Futility of fresh frozen plasma in the correction of coagulopathy prior to image-guided drainage of infected collections: Results from a prospective case–control study
Authors: Porchezhian Pradakshna , Arora Navneet , Gorsi Ujjawal , Singh Lakhvinder , Hans Rekha , Kumar Narender , Ahluwalia Jasmina , Malhotra Pankaj , Jain Arihant 
Published: February 2024

Abstract

BACKGROUND:
Fresh frozen plasma (FFP) is frequently used as prophylactic hemostatic therapy for correction of periprocedural coagulopathy. This practice is frequently based on the assumption that deranged international normalized ratio (INR) predicts the risk of periprocedural bleeding and that FFP transfusion is effective in mitigating the procedure-associated bleeding risks. There is limited evidence to support both these assumptions in the context of image-guided drainage of infected collections.

AIMS:
The study aimed to analyze the efficacy of weight-based standard FFP dose for correction of infection-associated coagulopathy in patients with clinicoradiologically diagnosed infected collections planned for image-guided drainage.

MATERIALS AND METHODS:
In this prospective case–control study, 229 patients with clinicoradiologically diagnosed infected abdominal collection(s) planned to undergo image-guided drainage were included. Cases and controls were defined as patients with baseline INR >1.2–3 (in the absence of any other bleeding diathesis) and INR ≤1.2, respectively. Cases received 10–15 mL/kg of FFP before drainage. Costs and time delays in drainage among the two groups, efficacy of plasma transfusion in the correction of coagulopathy, incidence of transfusion reactions, bleeding complications, and inhospital mortality were analyzed.

RESULTS:
There were 117 cases and 112 controls. A total of 445 FFP units were utilized. The median (interquartile range) time required from diagnosis of collection to the procedure was 25.3 (20.8–40.3) hours among cases and 16.4 (8.7–20.1) hours among controls (P < 0.001). FFP transfusion resulted in INR normalization (≤1.2) only in 7.9% of cases (n = 9). Among the 81 cases who had pretransfusion INR ≥1.5, INR improved to ≤1.5 in 49 (60.4%) patients. There was an average of 2.9% decrease in INR per unit of FFP transfused. No bleeding complications were noted in patients undergoing drainage despite a persistent deranged INR (>1.5) postplasma transfusion. Transfusion reactions occurred in 17/117 (14.5%) patients. There were no deaths among the controls while five patients died among the cases.

CONCLUSION:
Prophylactic FFP transfusion for infection-associated coagulopathy leads to a significant delay in lifesaving drainage procedures. Minority of patients attain normalization of INR with FFP transfusion.
Acute transfusion reaction and its associating factors: An insight from Indonesian National Referral Hospital
Authors: Wahidiyat Pustika Amalia , Marpaung Elida , Iskandar Stephen Diah , Pratanata Anastasia Michelle , Sitompul Nelly Erywaty 
Published: February 2024

Abstract

INTRODUCTION AND AIMS:
Remarkable progress has been made in controlling infection, leaving transfusion reaction a great concern following blood administration. Optimal hemovigilance is the key in ensuring transfusion safety, yet many centers’ system is still far below standard. Reported data are lacking from our part of the world, hence we aim to provide an insight into acute transfusion reaction profile from Indonesia’s National Referral Hospital to refine hemovigilance system, especially in a resource-constrained center.

SUBJECTS AND METHODS:
We collected transfusion data from Kiara, Cipto Mangunkusumo National Referral Hospital, Jakarta, throughout 2018. Data include age, sex, diagnosis, type of blood products received, reaction symptoms, and its severity, along with time to each reaction’s occurrence. We analyzed these data to find any significant association.

RESULTS:
Throughout 2018, there were a total of 25,798 blood transfusions. Among these, there were 133 of ATR reported (0.52%). Fresh frozen plasma, thrombocyte concentrate (TC), and packed red cells-regular (PRC-R) resulted in the highest reaction incidence where PRC elicited a fair amount of moderate-severe reactions (54.7%) while TC and plasma components mostly in mild reactions (71.4% and 80%). We also found a significant correlation between time to reaction onset with both types of blood products and patient’s diagnosis.

CONCLUSIONS:
Various recipient’s factors are paramount in predicting ATR and hence preventive strategies should be conducted in a more personalized way. We present the rationale to take into account patient’s diagnosis and types of blood product received to anticipate more serious reactions and in a timely manner.
Impact of early and empirical cryoprecipitate administration on the transfusion requirements in trauma patients with hemorrhagic shock
Authors: Bhandari Arun , Chaurasia Rahul , Sagar Sushma , Subramanian Arulselvi , Sinha Tej Prakash , Kumar Abhinav , Pandey Hem Chandra , Patidar Gopal Kumar , Bagaria Dinesh Kumar , Singh Yudhyavir 
Published: February 2024

Abstract

BACKGROUND:
Fibrinogen is the earliest coagulation factor falling to the critical levels in severely bleeding trauma patients. Early fibrinogen supplementation in these patients has been recommended to improve the patient outcomes. However, its role in reducing the overall transfusion requirement remains equivocal.

AIMS:
This study aimed to evaluate the effect of early cryoprecipitate (CRYO) administration on the transfusion requirement and the coagulation assays in trauma patients with hemorrhagic shock.

SETTINGS AND DESIGN:
An interventional study was conducted in two phases at level I trauma center. During the 1st phase (Group I), patients received blood components in accordance with current practices, whereas in the 2nd phase (Group II), patients received an additional CRYO (pool of 6 units) empirically within 90 min of admission.

METHODS:
Demographics, clinical, injury characteristics, transfusion requirements, blood counts, and coagulation assays were assessed for both the study groups.

STATISTICAL ANALYSIS:
The comparative analysis was done for blood component utilization and coagulations assays (prothrombin time, activated partial thromboplastin time, and fibrinogen levels) in both study groups.

RESULTS AND CONCLUSIONS:
A total of 50 patients in Group I and 51 patients in Group II were recruited. Demographics, clinical, injury characteristics, and laboratory investigations were comparable, except for heart rate, blood pressure, and injury scores. Significant reductions in red blood cell and platelet transfusions were observed, whereas the fresh-frozen plasma transfusions remained unaffected. The results of coagulation assays at 18–24 h were similar for both groups. Although no significant differences in fibrinogen levels were observed despite CRYO administration, decreased requirement for transfusions indicated an improved hemostasis in CRYO group.
Seroprevalence and risk factor relationship of hepatitis B core antibody among blood donors in Cañete, Peru
Authors: Iturrizaga-Blas Ruben , Sanchez-Jacinto Billy 
Published: February 2024

Abstract

BACKGROUND:
Hepatitis B virus is a global public health problem. There has been a growing interest in blood donors with a hepatitis B core antibody (anti-HBc) reactive and negative hepatitis B surface antigen as a marker for occult hepatitis B infection. The aim was to determine the seroprevalence and risk factors related to anti-HBc in blood donors at the Rezola Hospital in Cañete in 2019.

MATERIALS AND METHODS:
A cross-sectional study and sample size were 186 blood donors’ formats. The dependent variable was reactive anti-HBc, and the independent was sex, marital status, and age categories. Bivariate analysis included the Chi-square test, considered statistically significant at P<0.05. In addition, a general linear model was used to estimate prevalence ratios in crude analysis to assess factors associated with the outcome.

RESULTS:
A total of 202 blood donors were included in the study, and seroprevalence of anti-HBc in our study was 13.37% (n = 27), where 25 (92.59%) were male. A relationship was found between the variable’s age categories, marital status, and anti-HBc (P < 0.05). Seroprevalence of anti-HBc in men is 3.48 times compared to women (95% confidence interval [CI], 0.85–14.13; P = 0.081) and people older than 50 years was 4.45 times concerning the group of 18–29 years (95% CI, 1.17–16.87; P = 0.028) adjusted by sex and marital status.

CONCLUSIONS:
Seroprevalence in the Rezola Hospital is relatively low and is related to people over 50 years of age and married/cohabiting marital status.
Red cell antibodies or noise? A case series on reactivity against the ingredients in column matrix
Authors: Biswas Durba , Basu Debapriya , Reddy Mahua , Datta Suvro Sankha 
Published: February 2024

Abstract
Noise in the immunohematological investigations can be described as a false reactivity of red blood cells (RBCs) in serologic testing that is not related to the interaction of RBC antigens and antibodies that the test system is intended to detect. These false-positive reactions can cause confusion during the cross-matching and RBC antibody screening and may result in delays in patient transfusion. Although these antibodies are predominantly clinically insignificant, proper laboratory work-up is indicated to avoid misidentification of a clinically significant antibody as a noise. In this report, we describe the three rare cases where the reactivity was found against the ingredients of the column matrix (glass beads). It is imperative that such reactivity is recognized and resolved during the investigation of blood group discrepancies, positive RBC antibody screens and in cases of positive cross-matches.
Added Value of Mean Blood Pressure and Placental Growth Factor in the Early Detection of Pre-eclampsia among Gabonese Women
Authors: Lendoye Elisabeth , Minkobame Ulysse Pascal , Makoyo Komba Opheelia , Assoumou Obiang Pamphile , Nkene Eya'a Luce , Bisvigou Ulrich , Moukambi Lydie , Ndeboko Bénédicte , Ntamack Jacques Albert Bang , Ngoungou Edgard Brice , Siawaya Joël Fleury Djoba , Abessolo Félix Ovono , Meyé Jean François 
Published: February 2024

Abstract

Objective:
To evaluate the use of the Foetal Medicine Foundation (FMF) algorithm in routine practice for early pre-eclampsia (PE) screening in Libreville.

Materials and Methods:
We conducted a cohort study on pregnant women within their 11–13 + 6 weeks of gestation (WG). We had measured mean blood pressure (MBP), placental growth factor (PlGF), soluble Fms-like tyrosine kinase 1, Uterine Artery Pulsatility Index (UtA-PI) and resistance index (UtA-RI). Statistical analyses were considered significant for P < 0.05.

Results:
There were 30 participants. At the first quarter (T1), 36.7% of them were at high risk of PE according to the FMF algorithm and were consequently prescribed aspirin (100 mg/d). By the end of the observation period, we have found a 13% incidence of PE. MBP was higher in the higher risk PE group than in the lower risk group as early as the T1 (90 ± 6 vs. 81 ± 6 mmHg; P = 0.0007, threshold is >86 mmHg/area under the curve (AUC) = 0.86; P = 0.0012). It was the same for PlGF (58 ± 24 vs. 88 ± 38 pg/ml; P = 0.03; threshold is <71.98 pg/ml/AUC = 0.73; P = 0.03). At the second quarter (20–27 WG), biochemical markers did not change between the two groups. UtA-RI, UtA-PI and notch were unconclusive individually, but they are still very important for FMF algorithm application.

Conclusion:
Early detection of PE using the FMF algorithm is possible in routine practice in Gabon. MBP and PlGF levels at T1 seem to be very significant. However, the present study must continue to obtain the larger cohorts that would achieve more conclusive statistical analyses.
Medical Checks for Professional Football Players in Franceville, Gabon
Authors: Ekomy Hervé Martial , Abogo Joefred Mbogho , Begouabe Herman , Kinga Armel , Eboue Brice Angwe , Ekouaghe Laetitia Pauline Abang , Karmakar Jayanta , Obiang Cedric Sima 
Published: February 2024

AbstractThe Aim of the Study:To describe the clinical and non-clinical characteristics of Gabon footballers in the Haut-Ogooue Polyclinic in Franceville, Gabon, during visits, to assess whether they are not contraceptive to sports.Patients and Methods:A descriptive and analytical cross-sectional study was conducted in the city of Franceville, Gabon, in May 2022. The first and second divisions of footballers were subjected to medical examinations to determine whether they had any contraindications for playing sports, including clinical examinations, rest electrocardiograms (ECG), rest cardiac ultrasounds, chest X-rays, Rick-Dickson and biological checks.Results:The average age of 88 footballers (22–25 years) was 23 years. Blood pressure (BP) is abnormal in 19% of players, and alcohol and tobacco consumption is reported in 70% and 30%, respectively. Exercise adaptation was also closely associated with age (P= 0.00137724; P = 0.008974301), football position (P= 0.009957548;P= 0.006646182) and alcohol consumption (P= 0.000531971). Electrical and biological changes were 16% and 86.79%, respectively. Sinus bradycardia and first-degree atrioventricular block are the most common ECG abnormalities. Metabolic, inflammatory, infectious, electrolyte and anaemia syndromes were found in 22.64%, 24.53%, 19.81%, 7.55% and 12.26%, respectively. Midfielders and defenders have shown the greatest changes in biological parameters.Conclusion:Medical checks are essential to determine if sports are contraindicated, as they can help identify physiological and pathological conditions and improve the monitoring of athletes.
Placental Site Trophoblastic Tumour Mimicking Placenta Previa
Authors: Bukar Mohammed , Kawuwa Mohammed Bello , Nggada H. A. , Pindiga H. U. , Malgwi Adamu 
Published: February 2024

Abstract
We present a 42-year-old Nigerian woman who had three previous caesarean sections and is being managed conservatively for placenta previa. She underwent a caesarean hysterectomy on account of uncontrollable bleeding, and histopathology revealed a placental site trophoblastic tumour.
Ian Verstegen, The New Vienna School of Art History Fulfilling the Promise of Analytic Holism
Authors: Vidrih Rebeka 
Published: February 2024

Verstegnova študija t. i. nove dunajske umetnostnozgodovinske šole iz tridesetih let 20. stoletja ni povsem običajna historiografska predstavitev ključnih predstavnikov t. i. strukturne analize (Strukturanalyse), naslednikov velikih dunajskih umetnostnih zgodovinarjev z Aloisom Rieglom in Maxom Dvořákom na čelu, temveč je njen namen ambicioznejši. S svojo študijo teoretskih postavk in konceptov Hansa Sedlmayrja in Otta Pächta se Verstegen namreč vključuje v razpravo o pomenu, zastavkih in potencialnih usmeritvah sodobne umetnostnozgodovinske discipline.
Historical archaeology at the interstices between archaeology and history
Authors: Predovnik Katarina 
Published: February 2024

This paper explores the relationship between the disciplines of archaeology and history through the lens of historical archaeology. This is not a unified subdiscipline and has indeed been defined in various ways. Here, the term will be used as a shorthand for (later) medieval, post-medieval and contemporary archaeologies.
Historical archaeology is first and foremost archaeology focusing on material remains and producing knowledge claims about the past (history) from things. But it can complement and confront the data gleaned from the material sources with other types of evidence (textual, pictorial, oral), so it is an archaeology with texts. This represents a methodological and epistemological challenge. An uncritical reliance on textual information over the material has often been warned against as “the tyranny of the historical record”.
Many (historical) archaeologists have been inspired by various historiographical concepts and approaches, such as cultural history, the Annales school of social and economic history, Braudel’s concept of the longue-durée, the history of the everyday (Alltagsgeschichte), and microhistory. Conversely, the knowledge produced by archaeologists tends to be disregarded by most historians. This is unfortunate, as the material evidence offers important insights into past lifeworlds and should not be ignored.
AMMONIUM CONCENTRATIONS INDUCED CHANGES IN THE ASCORBIC ACID, CAROTENOID, PHENOLIC AND FLAVONOID CONTENT IN THE CULTURES OF Aglaonema simplex, AN AQUATIC PLANT
Authors: Abdullah-Asri Mohd-Ridwan , Ahmad Amirrudin , Noor-Hassim Muhamad-Firus , Ahmad Aziz 
Published: February 2024

Ammonium is one source of nitrogen for plants. In higher concentrations, ammonium causes toxicity to plants. The present study examined the effects of ammonium concentrations (0 to 45.0 mM) on biomass, α-tocopherol, ascorbic acid, chlorophyll, carotenoid, phenolic, flavonoid, and flavones levels in the aquatic plant, Aglaonema simplex culture. Results showed that ammonium concentration induced changes in the biomass and measured biochemicals in the plant. Ammonium at 36.0 mM produced the highest biomass (1.5-fold of dry weight), ascorbic acid (1.2-fold), and total phenolic (1.3-fold) after 28 days of treatment. Carotenoid, chlorophyll, and flavonoid content varied among the ammonium concentrations and depend on the culture period. Ammonium concentrations did not significantly influence (p > 0.05) the α-tocopherol content in the treated plants. The finding suggested that ascorbic acid and phenolic might act as shields to diminish the ammonium toxicity effect and can be induced by an appropriate ammonium concentration applied into the culture medium.
Analisis Faktor Ukuran Perusahaan, Struktur Kepemilikan, dan Profitabilitas terhadap Ketepatan Waktu Pelaporan Keuangan
Authors: Ferdianti Desi , Riswan  
Published: February 2024

Those studies goals are designed to observe the factor evaluation of company size, ownership structure, and profitability on the time of financial reporting. Thisstudies is absolutely primarily based on financial statements of banking corporations listed to Indonesia stock exchange. A focused sampling method became used within the sampling of this examine. The records evaluation technique used on this examine is logistic regression evaluation. The statistics used on this examine had been received from secondary statistics in the form of annual accounts of organizations listed in Indonesia stock trading (IDX 2018-2020). The consequences of this examine imply that ownership structure has a positive and insignificant effect on financial reporting timeliness, even if company size and profitability have a positive and significant effect on financial reporting timeliness.
Keywords: Size1; Ownership 2; Profitability3 ; On Timeliness 4
Pengaruh Kerja Sama Tim, Komunikasi, dan Komitmen terhadap Kinerja Karyawan di PDAM Tirta Deli
Authors: Lubis Imam Khairum Miza , Rukmini  , Sembiring Zamaluddin , Wibowo M. Rizaldy 
Published: February 2024

The purpose of this study was to determine the effect of teamwork, communication and commitment on employee performance at PDAM Tirta Deli either partially or simultaneously. This type of research uses primary data and secondary data. While data collection techniques using observation, questionnaires and interviews. The sample of PDAM Tirta Deli employees is 43 employees. Data analysis techniques using multiple linear regression analysis, hypothesis testing (t test and F test), and the coefficient of determination. The results of this study prove that partially it is known that the t-count of Teamwork (X1) is 2,704 > 1,682, Communication (X2) is 2,309 > 1,682, and Commitment (X3) is 2,158 > 1,622, then H0 is rejected and Ha is accepted, which means it influences Employee performance, and simultaneously it is known that the F-count value is 20,706> F-table 2.85, so there is an influence of teamwork, communication and commitment to employee performance at PDAM Tirta Deli.
Keywords: Teamwork, Communication, Commitment, Employee Performance
Pengaruh Tingkat Pendidikan, Pemahaman Akuntansi, dan Kesiapan Pelaku UMKM Terhadap Penerapan SAK EMKM Dalam Penyusunan Laporan Keuangan UMKM
Authors: Periska Vera , Yanti., SE.,M.Ak  , Rachpriliani., SE.,M.Ak Awaliawati 
Published: February 2024

This study aims to evaluate and examine the effect of the educational level of Micro, Small and Medium Enterprises (UMKM) actors, accounting knowledge, and readiness on the use of Micro, Small, and Medium Entity Financial Accounting Standards (SAK EMKM) in compiling MSME financial reports in districts. Karawang. This study uses a quantitative methodology with primary data collection. The sample for this study only consisted of SMEs based in Karawang Regency. The number of samples for this research is one hundred respondents. This research focuses on MSMEs in Karawang Regency. By using PLS and SmartPLS 3.0, analyze the relationship between the dependent and independent variables. The findings of this study indicate that the level of education, accounting knowledge, and readiness of MSME actors have a positive and significant effect on the implementation of SAK EMKM.
Keywords: Effect of education level, understanding of accounting, readiness of MSME actors, application of SAK EMKM