bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporalidad y simulacro del pasado medieval en el presente literario de la posmodernidad: la reformulación de la historia de Apolonio de Tiro en El delfín de Mark Haddon
Authors: Zubillaga Carina 
Published: November 2023

El objetivo principal de este trabajo es analizar cómo se recupera el pasado medieval en el presente de la posmodernidad, a través de la reformulación de la historia de Apolonio de Tiro en la reciente novela El delfín, de Mark Haddon. El enfoque de la investigación se centra en aquello que la novela destaca del relato medieval de las aventuras del héroe: el tema del incesto inicial entre el rey Antíoco y su hija, una joven abusada que adquiere protagonismo en la narración presente, junto con otras mujeres víctimas de la opresión en la historia. En el marco de los recientes debates acerca de la recuperación del pasado medieval, el análisis se centra en la reescritura de la historia de Apolonio y en las técnicas literarias que se emplean para actualizarla. Se pretende contribuir de esta forma a visibilizar temáticas actuales como la violencia de género, que El delfín desarrolla, de manera privilegiada, a través del simulacro de la historia y de la espacialización del tiempo como recursos narrativos.
Numerical modeling of wave-surge effects on barrier-island breaching in St. Joseph Peninsula during Hurricane Michael
Authors: Ma Mengdi , Huang Wenrui , Vijayan Linoj , Jung Sungmoon 
Published: November 2023

Abstract
Better understanding the effects of hurricane wave and storm surge on barrier-island breaching is important for both scientific research and coastal hazards mitigations. In this study, the 2D non-hydrodynamic Xbeach model has been applied to investigate interactions of hurricane wave, storm surge, and morphological processes in the case study of St. Joseph Peninsula during Category 5 Hurricane Michael. Model validations show a 2.45% average error and the 0.88 skill score between modeled and observed high water marks and bed elevations, respectively. Analysis of spatial distributions of currents and water levels indicates that a narrow area was overtopped at peak storm surge and wave. The gap was then quickly enlarged as the breaching area by wave-surge actions. By investigating foredune and peak dune along the central axis of breaching area, it shows that the foredune erosion on the sea side by wave-surge-current indirectly lead to the breach of the peak dune area in the barrier island. The Froude number shows a strong correlation with quick erosion of the barrier, indicating wave-surge supercritical flow is one of the major factors causing the barrier breaching. Results of cross sections of bed elevations and instantaneous surge-wave profiles at different storm surge stages reveal the evolution of the barrier-island breach. Results from this study provide valuable references for coastal hazard mitigation and resilience communities.
Exploring the Interaction of Enumeration and Perceptual Averaging Across Varied Presentation Durations
Authors: Sengupta Rakesh , Shukla Anuj , Pareek Sumit , Sultana Simra 
Published: November 2023

Abstract
Magnitude perception in the visual domain encompasses enumeration and perceptual averaging. Enumeration involves estimating the number of objects, while perceptual averaging entails perceiving the average value of a feature within an ensemble. This study investigates the interaction between these processes across varied presentation durations. In Experiment 1, participants engaged in two tasks: numerosity comparison and mean size estimation. We familiarized participants with a fixed numerosity (13) and mean size (50px) of a set of black dots. The individual dot sizes and their locations varied in each display. Test stimuli varied in numerosity and mean size. Participants compared either the numerosity or mean size of the set with the reference values. We determined the point of subjective equality (PSE) separately for number and size trials. The PSE for both trials closely approximated 1, indicating a more veridical representation (F (1,42) = 0.04421, p = 0.3917). We attributed this to participants having unrestricted time to respond. In Experiment 2, test stimuli appeared for durations of 68ms, 500ms, and 1s. For both Enumeration and Size, PSE values were close to one at 68ms. A 2-way ANOVA test revealed a statistically significant interaction between enumeration and size at the p = 0.002 level (F (2,80) = 9.96, p < 0.01). Experiment 1, with unrestricted response time, showed greater accuracy compared to Experiment 2, where test stimulus duration was restricted. Both experiments indicate that accurate estimation in numerosity and mean size tasks depends on presentation time.
Photoferrotrophy, BIF deposition, and iron-free oxygen oases in the Archean surface ocean
Authors: Crowe Sean , Ding Anyang , Zhao Guochun 
Published: November 2023

Abstract
Banded Iron Formations (BIFs) are both the world’s largest ore deposits and important geological archives that record the early evolution of the Earth-Life system. BIFs were likely deposited as the result of ferrous iron [Fe(II)] oxidation, precipitation, and sedimentation from iron-rich (ferruginous) seawater, mostly during the Archean Eon. Proposed mechanisms for iron oxidation include abiotic reactions with photosynthetic oxygen, reaction with oxygen catalyzed by iron-oxidizing bacteria (IOB), and anoxic oxidation by anoxygenic iron-oxidizing phototrophic bacteria (photoferrotrophs). These iron oxidation processes may have operated concurrently, but their relative contributions to BIF deposition have not been considered. Here, we developed a 1-D ferruginous ocean model incorporating abiotic iron cycling and the physiology of oxygenic phototrophs, microaerophilic IOB, photoferrotrophs, and iron-reducing bacteria. Our model shows that, under Archean ocean conditions, most iron oxidation and precipitation would have been driven by photoferrotrophy, with a small fraction by microaerophilic IOB and a negligible contribution from abiotic reactions. The combined activities of these pathways led to BIF deposition at rates in line with geological records and, importantly, allowed the development of an Fe(II)-free surface ocean conducive to the formation of oxygen oases and the proliferation of oxygenic phototrophs.
Teaser
Archean ocean simulation shows that photoferrotrophs dominated the precipitation of BIFs and promoted the formation of marine oxygen oases.
Is the Burden of Metastatic Lymph Node Stations a Prognostic Factor in Patients with Resected Lung Cancer? A Multicentre Study with Validation in Each T Stage
Authors: Çitak Necati , Erdoğu Volkan , Aksoy Yunus , Çiftçi Ayşegül , Yıldız Nisa , İşgörücü Özgür , Özdemir Servet , Köse Selçuk , Ceylan Kenan , Metin Muzaffer 
Published: November 2023

Abstract
Objectives
The burden of metastatic lymph node (LN) stations might reflect a distinct N subcategory with a more aggressive biology and behaviour than the traditional N classification.
Methods
Between 2008 and 2018, we analysed 1236 patients with pN1/2 lung cancer. When survival was analysed according to LN station metastasis, the number of metastatic LN stations that provided additional prognostic information was considered the optimal threshold. We performed the N prognostic subgrouping according to the thresholds for the number of metastatic LN stations with a maximum chi-square log-rank value. This was validated at each pT-stage.
Results
Survival showed stepwise statistical deterioration with an increase in the number of metastatic LN stations. According to survival analyses results, threshold values for the number of metastatic LN stations were determined and N prognostic subgrouping was created as sN-αlfa; one LN station metastases (n = 632), sN-βeta; two-three LN stations metastases (n = 505), and sN-Ɣamma; ≥4 LN stations metastasis (n = 99). The 5-year survival rate was 57.7% for sN-αlfa, 39.2% for sN-βeta, and 12.7% for sN-Ɣamma (chi-square log rank = 97.906, p < 0.001). We observed a clear tendency of deterioration of survival from sN-αlfa to sN-Ɣamma in the same pT stage, except for pT4 stage. Multivariate analysis showed that age (p < 0.001), sex (p = 0.002), tumour histology (p < 0.001), IASLC-proposed N subclassification (p < 0.001), and sN prognostic subgroups (p < 0.001) were independent risk factors for survival.
Conclusion
The burden of metastatic LN stations is an independent prognostic factor for survival in patients with lung cancer and could add different prognostic information to the N classification.
Enhancing Event Detection with Syntactic Information with Dependency-aided Graph Convolutional Networks
Authors: NG Swayamdipta , Ruman Chapman 
Published: November 2023

Abstract
In the realm of information extraction, event detection (ED) is a crucial subtask focused on identifying specific event instances in text. While integrating syntactic dependencies into graph convolutional networks has been validated as effective in previous research, these approaches often overlook the dependency label information, a rich linguistic resource beneficial for ED. This study introduces an innovative architecture, Dependency-aided Graph Convolution Networks (DaGCN), which leverages both syntactic structures and typed dependency labels. The core of DaGCN is an edge-aware node update module, designed to enrich word representations by incorporating syntactic connections through specific dependency types. Complementing this, a node-aware edge update module is introduced to refine relation representations with context-specific details, enhancing the overall effectiveness. Evaluated on the ACE2005 dataset, our DaGCN model significantly outperforms established baselines, highlighting the value of integrating dependency labels in ED tasks.
Medical and health workers in international migration and healthcare system performance in Abia state, Nigeria.
Authors: Kenneth Iroegbu Uzochukwu 
Published: November 2023

Abstract
This study examines the link between medical and health workers international migration and healthcare system performance in Abia State, Nigeria. The study adopts the neo-classical and push-pull theoretical frameworks. These theories evaluates the relationship between weak and uncoordinated state policy and threats to the objective of self-sufficiency, poor medical and health practice and working conditions as a factor that motivates medical and health workers’ continuous migration on in Abia State, Nigeria. In our research methods, we adopted the quantitative and qualitative research design, while the unstructured interview and documentary method of data collection were adopted to generate data from staff of Federal Medical Center (FMC) and secondary sources such as text books, journals, conference papers, periodicals, as well as relevant internet website. We used both quantitative and qualitative descriptive method to analyze both primary and secondary data. Findings of the study reveals the motivations to migrate by medical and health workers as-poverty, insufficient or poorly equipped institutions, lack or shortage in manpower and absence of basic facilities for career development. Medical and health workers’ become attracted to migrate because of higher remuneration, adequate infrastructure, excellent reward for hard work, improved educational opportunities, security of life and property, adequate research funding and numerous incentives and the push factors include poor remuneration, poor infrastructure and leadership, poor medical technology and lack of incentives. The study discovered a significant relationship between work – related stress on healthcare workers and service delivery, work over – load and increase in work stress, and poor managerial relationship/support and staff attitude to service delivery. Centrally, the research recommends that there is a call to adopt and implement an integrated policy that will retain skilled health professionals in the country for the benefit of the main users of public health systems and the poor.
Title: LAMC2 promotes oral squamous cell carcinoma growth by activating the p-ERK/c-Myc signaling pathway
Authors: Qiao Bo , Jin Nenghao , Zhao Min , Zhu Liang , Li Liangbo , Gu Bin , Wen Ning , Zhang Haizhong 
Published: November 2023

Abstract
Purpose Oral squamous cell carcinoma (OSCC) is one of the most common types of head and neck carcinoma. Limited therapies are available for OSCC due to lack of molecular therapeutic targets.Methods Bioinformatics analysis, in vitro experiments and animal model studies were performed to elucidate the crucial role and clinical significance of LAMC2 in the progression of OSCC. And we examined the mRNA and protein levels of LAMC2 in human OSCC tissue to explore the biological significance of LAMC2.Results We identified Laminin γ2 (LAMC2), a crucial oncoprotein, were upregulated in human OSCC samples in TCGA datasets. The upregulated LAMC2 was related to poorer survival rates, increased the risk of OSCC-specific mortality, and there were significant differences in survival between the LAMC2 high and low expression groups. We also validated that the mRNA and protein expression of LAMC2 were upregulated in human OSCC samples compared with the para-tumor tissues. LAMC2 overexpression significantly enhanced cell proliferation, invasion and migration. Mechanistically, overexpression of LAMC2 could increase the expression levels of p-ERK and c-Myc, while knockdown of LAMC2 resulted in the opposite effect. Moreover, the ERK inhibitor decreased ERK phosphorylation and reversed the OSCC phenotype induced by LAMC2 overexpression.Conclusion LAMC2 enhances the cell proliferation, invasion and migration of OSCC cells via the p-ERK/c-Myc axis, suggesting the crucial role of LAMC2 in the progression of OSCC and small molecule inhibitors targeting LAMC2 might be an effective treatment for OSCC patients.
Mid-term Clinical Outcomes of Totally Thoracoscopic Repair for Mitral Regurgitation in Barlow’s Disease
Authors: Zhang Lin , Cui Huimin , Shen Hong , Li Dong , Li Lianggang , Shen Hua , Jiang Shengli 
Published: November 2023

Abstract
Objective
This study aimed to confirm the safety and feasibility of totally thoracoscopic repair for mitral regurgitation (MR) in Barlow’s disease.
Methods
From June 2018 to December 2022, 21 consecutive Barlow's disease patients (aged 33 ± 12 years; 57.1% male) underwent totally thoracoscopic mitral valve (MV) repair with leaflets folding, multiple artificial chordae implantation and ring annuloplasty. The safety and feasibility of this technique was evaluated by its mid-term clinical outcomes.
Results
There was no operative death or complications. The mean cardiopulmonary bypass (CPB) time was 190 ± 41 (128–267) min, and the aortic cross-clamp time was 145 ± 32 (66–200) min. The average number of artificial chordae implantation was 2.9 ± 0.7 (1–4) pairs. During a mean follow-up time of 25.6 ± 15.2 (1–52) months, all patients showed persistent effective valve function with a mean transvalvular gradient of 1.995 ± 1.543 (1.0–6.0) mmHg and no significant MR (10 cases of mild MR) or systolic anterior motion (SAM).
Conclusions
Totally thoracoscopic repair was a safe, effective, and reproducible procedure with satisfied mid-term clinical outcomes for MR in Barlow’s disease. However, further randomized and long-term follow-up studies were warranted to determine its clinical effects.
High concentration of iron ions contributes to ferroptosis-mediated testis injury
Authors: Liu Chaoying , Wang Ye , Xia Huili , Liu Yingying , Yang Xinfeng , Yuan Xiongyan , Chen Jiahui , Wang Mingcheng , Li Enzhong 
Published: November 2023

Abstract
In order to explore the effect of different concentrations of iron ions on ferroptosis in mouse testes, Kunming mice were randomly divided into control group (normal saline), low iron concentration group (25mg/kg), high iron concentration group (70mg/kg) and deferoxamine group (40mg/kg). The mice were injected continuously for 7 days and their body weight was measured. At the end of the experiment, the organ weight, sperm count, and malformation rate were measured. Testicular tissue, the pathological and ultrastructural changes in spermatogenic tubules were also observed by using hematoxylin eosin (HE) staining and transmission electron microscopy. The changes in transcription levels of related genes and serum biochemical indicators were measured in mouse testicular tissues. The results showed that higher iron concentration may inhibit the growth of mice, reduce the organ coefficients of testis, heart, and liver, and increase the rate of sperm malformation and mortality. Supplementation of iron ion in high concentration can negatively affect the male reproductive system by reducing the sperm count and causing malformation and structural damage in seminiferous tubules and sperm cells. In addition, the iron concentration also affected the immune response and blood coagulation ability by influencing the red blood cells, white blood cells and platelets. The results showed that iron ions may affect mice testicular tissue and induce ferroptosis by altering the expression of ferroptosis related genes. Though, the degree of effect was different for the different concentrations of iron ions. The study also revealed the potential role of deferoxamine to inhibit the occurrence of ferroptosis. Though, the damages caused to the testis by deferoxamine supplementation suggests the need for further researches in this direction.
Large Language Models' Understanding of Math: Source Criticism and Extrapolation
Authors: Yousefzadeh Roozbeh , Cao Xuenan 
Published: November 2023

Abstract
It has been suggested that large language models such as GPT-4 have acquired some form of understanding beyond the correlations among the words in text including some understanding of mathematics as well. Here, we perform a critical inquiry into this claim by evaluating the mathematical understanding of the GPT-4 model. Considering that GPT-4's training set is a secret, it is not straightforward to evaluate whether the model's correct answers are based on a mathematical understanding or based on replication of proofs that the model has seen before. We specifically craft mathematical questions which their formal proofs are not readily available on the web, proofs that are more likely not seen by the GPT-4. We see that GPT-4 is unable to solve those problems despite their simplicity. It is hard to find scientific evidence suggesting that GPT-4 has acquired an understanding of even basic mathematical concepts. A straightforward way to find failure modes of GPT-4 in theorem proving is to craft questions where their formal proofs are not available on the web. Our finding suggests that GPT-4's ability is to reproduce, rephrase, and polish the mathematical proofs that it has seen before, and not in grasping mathematical concepts. We also see that GPT-4's ability to prove mathematical theorems is continuously expanding over time despite the claim that it is a fixed model. We suggest that the task of proving mathematical theorems in formal language is comparable to the methods used in search engines such as Google while predicting the next word in a sentence may be a misguided approach, a recipe that often leads to excessive extrapolation and eventual failures. Prompting the GPT-4 over and over may benefit the GPT-4 and the OpenAI, but we question whether it is valuable for machine learning or for theorem proving.
Surface heat exceeds air temperature regulates topsoil quality over the arid-cold regions
Authors: Huang Jianping , Han Dongliang , Liu Xiaoyue , Fu Li , Ding Lei , Zhang Guolong , Li Changyu , Yang Fan 
Published: November 2023

Abstract
Transpiration cooling, induced by vegetation greening in a warming climate, controls changes in soil quality, which affects plant productivity, establishing a positive feedback. However, this feedback mechanism for soil quality is largely unknown. Here we analyze empirical data from microbial, soil, plant and climatic properties (all n=30), to explore the determinants of soil quality and build a its mechanism framework over broad environmental gradients. We find high topsoil quality (significantly different at P<0.01) is associated with high nutrient content, microbial biomass, and physico-chemical protection under low sensible heat flux release. Physiochemical mechanisms play an extremely key role in regulating the topsoil quality than biological mechanisms. Models suggest that vegetation greening, which could lead to a decrease in sensible heat and an increase in latent heat. The dependence of topsoil quality on surface energy dynamic changes should be considered in Ecological Meteorological Models to accurately predict land-atmosphere feedbacks in changing environments.
The Impact of The New Trends and Innovations in Five-Star Resorts in Hurghada City, Egypt on Guest Satisfaction
Authors: Yousry Fahd Mohamed , Saad Sameh Gamal , Mohamed Fatma Abdelaal 
Published: November 2023

Abstract
Egypt is a country that highly relies on the tourism industry. Following the new trends and innovations are significant for development of resorts. In this study, researcher analyzed trends, challenges and innovations in selected five-star resorts in Hurghada City. This paper further discussed innovation in selected five-star resorts, and the impact affected by innovations and innovative practices in resorts. Qualitative research techniques were used in this study. In-depth interviews were conducted in English with three officials from selected five-star resorts to collect primary data. Observation method was also employed to observe the surroundings and layouts in selected resorts. Secondary data were mainly collected from journal articles, reports, and books and websites. The study employed thematic analysis and content analysis to express findings. The results showed innovation outputs which belong to product innovation, service innovation and administrative innovation respectively. Findings also indicated that resorts utilized both interior and exterior approaches to follow up new trends and innovation. Furthermore, these innovations and innovative practices improved guests’ satisfaction and business performance for the resorts.