bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mythical Elements
Authors: Kingsmill Slg Edmée 
Published: November 2023

Abstract
The perception that myth permeates the Song of Songs lifts a veil on much that otherwise remains opaque to the understanding. But the term ‘myth’ has become — if it ever was not—problematic, and its misuse is warned against by every writer on the subject. Trusting that I have taken all these warnings to heart, I will pass straight to one writer, J. W. Rogerson, who summarizes twelve different senses of myth in his book Myth in Old Testament Interpretation, and whose summary of the eleventh seems particularly applicable to the present case:
Myth is a necessary way of speaking of transcendent reality.
The Eros of God
Authors: Kingsmill Slg Edmée 
Published: November 2023

Abstract
In a dictionary entry called ‘Spiritual Marriage’, Benedicta Ward writes:
The term is generally used to describe the highest degree of contemplative prayer experienced by the mystic. This usage was established by St Teresa of Avila and St John of the Cross in the sixteenth century, but it is a term which has a much longer history. The use of the image of marriage to describe the union of the soul with God is found in pre-Christian sources, both Jewish and Platonic. Philo of Alexandria, for instance, sees the union of the soul with God in nuptial terms (De Cherubim, 42–52) and Gnostic writings describe the return of the soul to unity with the divine in terms of the marriage of Sophia with the Lord. It is, however, in the OT that the image is most clearly used, in describing the relationship of God to Israel.
Wounding Triggers Wax Biosynthesis in Arabidopsis Leaves in an Abscisic Acid–Dependent and Jasmonoyl-Isoleucine-Dependent Manner
Authors: Lewandowska Milena , Zienkiewicz Krzysztof , Zienkiewicz Agnieszka , Kelly Amélie , König Stefanie , Feussner Kirstin , Kunst Ljerka , Feussner Ivo 
Published: November 2023

Abstract
Wounding caused by insects or abiotic factors such as wind and hail can cause severe stress for plants. Intrigued by the observation that wounding induces expression of genes involved in surface wax synthesis in a jasmonoyl-isoleucine (JA-Ile)-independent manner, the role of wax biosynthesis and respective genes upon wounding was investigated. Wax, a lipid-based barrier, protects plants both from environmental threats and from an uncontrolled loss of water. Its biosynthesis is described to be regulated by abscisic acid (ABA), whereas the main wound signal is the hormone JA-Ile. We show in this study that genes coding for enzymes of surface wax synthesis are induced upon wounding in Arabidopsis thaliana leaves in a JA-Ile-independent but an ABA-dependent manner. Furthermore, the ABA-dependent transcription factor MYB96 is a key regulator of wax biosynthesis upon wounding. On the metabolite level, wound-induced wax accumulation is strongly reduced in JA-Ile-deficient plants, but this induction is only slightly decreased in ABA-reduced plants. To further analyze the ABA-dependent wound response, we conducted wounding experiments in high humidity. They show that high humidity prevents the wound-induced wax accumulation in A. thaliana leaves. Together the data presented in this study show that wound-induced wax accumulation is JA-Ile-dependent on the metabolite level, but the expression of genes coding for enzymes of wax synthesis is regulated by ABA.
Sugarcane mosaic virus employs 6K2 protein to impair ScPIP2;4 transport of H2O2 to facilitate virus infection
Authors: Zhang Hai , Yang Zongtao , Cheng Guangyuan , Luo Tingxu , Zeng Kang , Jiao Wendi , Zhou Yingshuan , Huang Guoqiang , Zhang Jisen , Xu Jingsheng 
Published: November 2023

Abstract
Sugarcane mosaic virus (SCMV), one of the main pathogens causing sugarcane mosaic disease, is widespread in sugarcane (Saccharum spp. hybrid) planting areas and causes heavy yield losses. RESPIRATORY BURST OXIDASE HOMOLOG (RBOH) NADPH oxidases and plasma membrane intrinsic proteins (PIPs) have been associated with the response to SCMV infection. However, the underlying mechanism is barely known. In the present study, we demonstrated that SCMV infection upregulates the expression of ScRBOHs and the accumulation of hydrogen peroxide (H2O2), which inhibits SCMV replication. All eight sugarcane PIPs (ScPIPs) interacted with SCMV-encoded protein 6K2, whereby two PIP2s (ScPIP2;1 and ScPIP2;4) were verified as capable of H2O2 transport. Furthermore, we revealed that SCMV-6K2 interacts with ScPIP2;4 via transmembrane domain 5 to interfere with the oligomerization of ScPIP2;4, subsequently impairing ScPIP2;4 transport of H2O2. This study highlights a mechanism adopted by SCMV to employ 6K2 to counteract the host resistance mediated by H2O2 to facilitate virus infection and provides potential molecular targets for engineering sugarcane resistance against SCMV.
HD–Zip I protein LlHOX6 antagonizes homeobox protein LlHB16 to attenuate basal thermotolerance in lily
Authors: Wu Ze , Li Ting , Zhang Yinyi , Zhang Dehua , Teng Nianjun 
Published: November 2023

Abstract
Homeodomain–leucine zipper (HD–Zip) I transcription factors are crucial for plant responses to drought, salt, and cold stresses. However, how they are associated with thermotolerance remains mostly unknown. We previously demonstrated that lily (Lilium longiflorum) LlHB16 (HOMEOBOX PROTEIN 16) promotes thermotolerance, whereas the roles of other HD–Zip I members are still unclear. Here, we conducted a transcriptomic analysis and identified a heat-responsive HD–Zip I gene, LlHOX6 (HOMEOBOX 6). We showed that LlHOX6 represses the establishment of basal thermotolerance in lily. LlHOX6 expression was rapidly activated by high temperature, and its protein localized to the nucleus. Heterologous expression of LlHOX6 in Arabidopsis (Arabidopsis thaliana) and overexpression in lily reduced their basal thermotolerance. In contrast, silencing LlHOX6 in lily elevated basal thermotolerance. Cooverexpressing or cosilencing LlHOX6 and LlHB16 in vivo compromised their functions in modulating basal thermotolerance. LlHOX6 interacted with itself and with LlHB16, although heterologous interactions were stronger than homologous ones. Notably, LlHOX6 directly bounds DNA elements to repress the expression of the LlHB16 target genes LlHSFA2 (HEAT STRESS TRANSCRIPTION FACTOR A2) and LlMBF1c (MULTIPROTEIN BRIDGING FACTOR 1C). Moreover, LlHB16 activated itself to form a positive feedback loop, while LlHOX6 repressed LlHB16 expression. The LlHOX6–LlHB16 heterooligomers exhibited stronger DNA binding to compete for LlHB16 homooligomers, thus weakening the transactivation ability of LlHB16 for LlHSFA2 and LlMBF1c and reducing its autoactivation. Altogether, our findings demonstrate that LlHOX6 interacts with LlHB16 to limit its transactivation, thereby impairing heat stress responses in lily.
Development and Validation of a TaqMan Multiplex Real-Time PCR Assay for High-Throughput Quantification of Fusarium graminearum Biomass in Barley Spikes and Grains
Authors: Navasca Abbeah , Dangi Sandesh , Baldwin Suzette Arcibal , Jin Zhao , Baldwin Thomas 
Published: November 2023

Fusarium head blight (FHB) is a devastating disease primarily caused by Fusarium graminearum that commonly affects North American small grains. Although the disease causes visible symptoms, the more pressing concern is the contamination of grain with trichothecene toxins, especially deoxynivalenol (DON), which can cause toxicity in humans and animals by inhibiting protein biosynthesis. The DON levels are more critical when breeding for resistance, but this does not account for pathogen infection and disease severity. To link DON and Fusarium infection, we optimized and validated a real-time multiplex quantitative PCR protocol for high-throughput quantification of Fusarium biomass based on the Tri5 gene, which encodes trichodiene synthase, the first enzyme involved in trichothecene toxin production. The primers and probes were designed to measure the abundance of Tri5 and normalized to the barley actin gene. The assay is repeatable, robust, and sensitive, up to 0.003 ng/µl of F. graminearum and 0.3 ng/µl of barley DNA. The method is cost-effective and has the potential to quantify Fusarium biomass, monitor disease progression, and determine DON levels in barley spikes and harvested grains. [Formula: see text] Copyright © 2024 The Author(s). This is an open access article distributed under the CC BY-NC-ND 4.0 International license .
Continuum kinematics with incompatible–compatible decomposition
Authors: Goldshtein Vladimir , Mariano Paolo Maria , Mucci Domenico , Segev Reuven 
Published: November 2023

We present a framework for the kinematics of a material body undergoing anelastic deformation. For such processes, the material structure of the body, as reflected by the geometric structure given to the set of body points, changes. The setting we propose may be relevant to phenomena such as plasticity, fracture, discontinuities and non-injectivity of the deformations. In this framework, we construct an unambiguous decomposition into incompatible and compatible factors that includes the standard elastic–plastic decomposition in plasticity.This article is part of the theme issue ‘Foundational issues, analysis and geometry in continuum mechanics’.
Seismic reliability analysis of slope in spatially variable soils using multiple response surfaces
Authors: Li Chunli , Li Liang , Cheng Yungming , Xu Liang , Yu Guangming 
Published: November 2023

PurposeThis paper aims to develop an efficient algorithm combining straightforward response surface functions with Monte Carlo simulation to conduct seismic reliability analysis in a systematical way.Design/methodology/approachThe representative slip surfaces are identified and based on to calibrate multiple response surface functions with acceptable accuracy. The calibrated response surfaces are used to determine the yield acceleration in Newmark sliding displacement analysis. Then, the displacement-based limit state function is adopted to conduct seismic reliability analysis.FindingsThe calibrated response surface functions have fairly good accuracy in predicting the yield acceleration in Newmark sliding displacement analysis. The seismic reliability is influenced by such factors as PGA, spatial variability and threshold value. The proposed methodology serves as an effective tool for geotechnical practitioners.Originality/valueThe multiple sources of a seismic slope response can be effectively determined using the multiple response surface functions, which are easily implemented within geotechnical engineering.
Sustainability and stakeholder theory: a processual perspective
Authors: Valentinov Vladislav 
Published: November 2023

PurposeSustainability has long been known to present an epistemic challenge. In the corporate setting, this challenge translates into the difficulties experienced by managers not only in devising solutions to corporate sustainability problems, but even in developing the awareness of the latter. The paper explores how these difficulties may be overcome by corporate stakeholder management policies.Design/methodology/approachThe paper develops a conceptual framework that reconstructs the Hayekian theory of market process in the context of Williamson's (1996) distinction between autonomous and cooperative adaptation.FindingsApplying the Hayekian theory of market process to the process of engagement and collaboration of corporate stakeholders, the paper shows how the latter process may address the epistemic challenge of corporate sustainability and derives implications for the design of business models for sustainability.Originality/valueThe paper informs stakeholder theory in two ways: first, stakeholder theory is given a novel justification in terms of reflecting the growing prominence of cooperative adaptation and second, corporate stakeholder management is shown to be crucial for maximizing not only economic but also sustainability performance.
The psychology of green behavior: when growth mindset, peer influence and warm glow meet the individual self
Authors: Rahnama Haratbar Hassan , Saeedikiya Mehrzad , Seif Mohammad Hassan 
Published: November 2023

PurposeThis study in Iran examined the role of internal and external psychological factors that affected green purchase intention. Moreover, it examined these variables' direct and indirect effects and green purchase intention on green purchase behavior.Design/methodology/approachAn extended version of the theory of planned behavior (TPB) was employed, based on which a theoretical model was designed to reach the authors’ aim. An online questionnaire was used to collect data. For data analysis, confirmatory factor analysis, structural equation modeling, the bootstrapping method and the Preschool Language Scale (PLS) product-indicator approach were conducted to test the proposed conceptual model.FindingsResults show that self-identity, self-interest, self-efficacy and a growth mindset have a positive impact on green purchase intention. However, the study found no predictive effect from peer influence and warm glow. In addition, self-efficacy and green purchase intention significantly affect green purchase behavior. The study reveals that green purchase intention substantially mediates the relationship between self-interest, growth mindset, warm glow and green purchase behavior. Further, warm glow moderates the impact of peer influence, self-identity and self-efficacy on green purchase intention. This study emphasizes the critical role of dispositional factors on green purchase intention and behavior.Originality/valueFew studies consider the effect of the individual self, a growth mindset, a warm glow and peer influence on green purchase intention simultaneously. In addition, the authors introduced a different version of the TPB model. Further, this research also conducted how these variables, directly and indirectly, affect green purchase behavior.
Wireless Emergency Alerts and organisational response: Instructing and adjusting information in alerts
Authors: Cain Lauren B. , Sutton Jeannette , Olson Michele K. 
Published: November 2023

AbstractIn the United States, alerting authorities are authorized by the Federal Emergency Management Agency (FEMA) to notify the public of imminent hazards and threats by sending Wireless Emergency Alerts (WEAs) through the Integrated Public Alert and Warning System (IPAWS). Although recent efforts have been made to examine historical WEA compliance with frameworks such as Mileti and Sorenson's (1990) Warning Response Model, less attention has been paid to information included in WEAs that is not prescribed by message design frameworks from risk communication scholarship. This paper explores the presence of Situational Crisis Communication Theory's (SCCT) instructing and adjusting information in terse mobile alerts. The authors conducted a content analysis of 4777 WEAs sent between 2019 and 2022 to determine how often and in which contexts (i.e., hazard types, 90‐ or 360‐character messages) these strategies are used. We find that the limited definition of adjusting information used in prior research (e.g., direction to mental health resources) is rarely included in WEAs. Additionally, we identify differences in use by message length (90‐ vs. 360‐characters) and hazard type. We conclude that adjusting information in WEAs most frequently takes the form of organisational response information, thereby amending prior definitions of adjusting information to more closely align with the objectives and goals of warning message design.
Effect of canakinumab on frailty: A post hoc analysis of the CANTOS trial
Authors: Orkaby Ariela R. , Thomson Aerin , MacFadyen Jean , Besdine Richard , Forman Daniel E. , Travison Thomas G. , Ridker Paul M. 
Published: November 2023

AbstractAlthough inflammation is strongly associated with frailty, whether medications that lower inflammation decrease frailty is unclear and randomized trial evidence is scant. We sought to test whether canakinumab, a therapeutic monoclonal antibody that inhibits IL‐1β and reduces C‐reactive protein (CRP), can lower frailty risk. This was a post hoc analysis of the Canakinumab ANti‐inflammatory Thrombosis Outcome Study (CANTOS), a randomized double‐blind placebo‐controlled trial of 10,061 stable postmyocardial infarction patients randomized to subcutaneous canakinumab once every 3 months. Incident frailty was measured using a 34‐item cumulative‐deficit Frailty Index (FI). Time‐to‐event analysis using intent to treat. A total of 9942 CANTOS participants had data to calculate a baseline FI. Median age was 61 (IQR 54–68); 74% were male, 12% Asian, 3% Black, 80% White, and 16% Hispanic/Latino. At baseline, mean FI score was 0.12 and 13% were frail using a cutoff of 0.2. Over 5 years, 1080 participants (12.5%) became frail and mean FI scores increased to 0.14. There was no effect on frailty incidence according to randomization to any canakinumab dose versus placebo over time, HR 1.03 (0.91–1.17), p = 0.63. Results were similar using phenotypic frailty. Additionally, the primary findings of CANTOS in terms of canakinumab‐associated cardiovascular event reduction were unchanged in analyses stratified by baseline frailty. In conclusion, among stable adult patients with atherosclerosis, random allocation to interleukin‐1b inhibition with canakinumab versus placebo did not lower risk of incident frailty over 5 years. More randomized data are needed to understand the role of targeted anti‐inflammatory medications for frailty prevention in older adults.
How moral bioenhancement affects perceived praiseworthiness
Authors: Lucas Simon , Douglas Thomas , Faber Nadira S. 
Published: November 2023

AbstractPsychological literature indicates that actions performed with the assistance of cognition‐enhancing biomedical technologies are often deemed to be less praiseworthy than similar actions performed without such assistance. This study examines (i) whether this result extends to the bioenhancement of moral capacities, and (ii) if so, what explains the effect of moral bioenhancement on perceived praiseworthiness. The findings indicate that actions facilitated by morally bioenhanced individuals are considered less deserving of praise than similar actions facilitated by ‘traditional’ moral enhancement—for example, moral self‐education. This diminished praise does not seem to be driven by an aversion to (moral) bioenhancement per se. Instead, it appears to be primarily attributable to a perceived lack of effort exerted by bioenhanced individuals in the course of their moral enhancement. Our findings advance the philosophical discourse on the foundations of praise in the context of moral bioenhancement by elucidating the empirical basis underlying some assumptions commonly employed to argue for or against the permissibility of moral bioenhancement.
Mechanisms linking cerebrovascular dysfunction and tauopathy: Adding a layer of epiregulatory complexity
Authors: Kim Yoon A. , Mellen Marian , Kizil Caghan , Santa‐Maria Ismael 
Published: November 2023

Intracellular accumulation of hyperphosphorylated misfolded tau proteins are found in many neurodegenerative tauopathies, including Alzheimer's disease (AD). Tau pathology can impact cerebrovascular physiology and function through multiple mechanisms. In vitro and in vivo studies have shown that alterations in the blood–brain barrier (BBB) integrity and function can result in synaptic abnormalities and neuronal damage. In the present review, we will summarize how tau proteostasis dysregulation contributes to vascular dysfunction and, conversely, we will examine the factors and pathways leading to tau pathological alterations triggered by cerebrovascular dysfunction. Finally, we will highlight the role epigenetic and epitranscriptomic factors play in regulating the integrity of the cerebrovascular system and the progression of tauopathy including a few observartions on potential therapeutic interventions.LINKED ARTICLESThis article is part of a themed issue From Alzheimer's Disease to Vascular Dementia: Different Roads Leading to Cognitive Decline. To view the other articles in this section visit http://onlinelibrary.wiley.com/doi/10.1111/bph.v181.6/issuetoc
Interactive effects of increased nestbox temperature and vitamin E on nestling growth are attenuated by plasticity in female incubation effort
Authors: Duncan Paige A. , Tauber Ashley M. , Sakaluk Scott K. , Thompson Charles F. 
Published: November 2023

AbstractIn recent years, temperatures have increased globally, and nestlings of many bird species are likely regularly exposed to increased temperatures both pre‐ and post‐natally. Even small increases in nest temperature during incubation affect offspring growth and survival in a variety of species, one cause of which is thought to be increased production of pro‐oxidants in embryos and nestlings. Defences marshalled in response to this oxidative stress could, in turn, result in trade‐offs that lead to reduced survival or growth. If so, any downstream negative effects on nestlings of increased ambient temperatures during incubation could be counteracted by increasing their antioxidant intake. We predicted, therefore, that dietary supplements of an antioxidant would reduce or eliminate any detrimental effects on nestling growth and survival of experimentally increased nest temperature during the incubation period. We employed a split‐brood design in which we increased the nest temperature of entire clutches and, after hatching, provided dietary supplements of the antioxidant vitamin E to half of the nestlings within broods. We also recorded female incubation and provisioning behaviour to control for the possibility that heating nests might also influence maternal behaviour. There was a significant interaction between nestbox heating treatment and vitamin E treatment in their effect on nestling mass, a trait that is positively correlated with survival and future reproductive success in the study population. Vitamin E supplementation promoted increased nestling mass in heated nests, whereas it had the opposite effect in control nests but these effects were weak. Heating significantly affected female incubation behaviour, with females in heated nestboxes investing less in incubation than those in unheated boxes. These results suggest that within at least some range of expected increased ambient temperatures during the 21st century, effects of climate change on nestling bird development can be mitigated by adjustments in female incubation behaviour.
Chemosensory afference in the tentacle nerve of Lymnaea stagnalis
Authors: Ucciferri Carmen C. , Wyeth Russell C. 
Published: November 2023

AbstractAlthough the neural control of behavior has been extensively studied in gastropods, basic gaps remain in our understanding of how sensory stimuli are processed. In particular, there is only patchy evidence regarding the functional roles of sense organs and the extensive peripheral nervous system they contain. Our goal was to use extracellular electrophysiological recordings to confirm the chemosensory role of the tentacles in the great pond snail, Lymnaea stagnalis. Employing a special twin‐channel suction electrode to improve signal‐to‐noise ratio, we applied three food odors (derived from earthworm‐based food pellets, algae‐based pellets, and fresh lettuce) to a reduced preparation of the tentacle while recording neuronal activity in the tentacle nerve. Responses were assessed by comparing average spike frequencies produced in response to saline flow with and without odors. We report stronger neuronal responses to earthworm‐based food odors and weaker responses to algae‐based food odors. There were no clear neuronal responses produced when lettuce food odor or control saline was applied to the tentacle. Overall, our results provide strong evidence for the chemosensory role of the tentacles in navigation behavior by L. stagnalis. Although it is unclear whether the differences in neuronal responses to different odors are a technical consequence of our recording system or a genuine feature of the snail sensory system, these results are a useful foundation for further study of peripheral nervous system function in gastropods.