bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cardiovascular risk factors and kidney function among automobile mechanic and their association with serum heavy metals in Southwest Nigeria: A cross-sectional study
Authors: Adejumo Oluseyi Ademola , Enikuomehin Adenike Christianah , Ogunleye Adeyemi , Osungbemiro Walter Bamikole , Adelosoye Alex Adedotun , Akinbodewa Ayodeji Akinwumi , Lawal Olutoyin Morenike , Ngoka Stanley Chidozie , Junaid Oladimeji Adedeji , Okonkwo Kenechukwu , Alli Emmanuel Oladimeji , Oloyede Rasheed Olanshile 
Published: October 2023

Introduction
The burden of cardiovascular disease (CVD) is huge due to its associated morbidity, mortality and adverse socio-economic impact. Environmental pollution as a risk factor contributes significantly to the burden of CVD, especially in the low and middle income countries. One of the effective strategies to reduce CVD burden is to prevent or detect cardiovascular risk factors early in at-risk population. This study determined some cardiovascular risk factors, kidney function, and their association with heavy metals among automobile mechanics.

Method
This was a cross-sectional study involving 162 automobile mechanics and 81 age and sex matched controls. Serum levels of lead, cadmium and some cardiovascular risks were assessed and compared in the two groups. Associations between serum lead, cadmium and some cardiovascular risks were determined using correlation analysis. P value of <0.05 was taken as significant.

Results
The mean ages of the automobile mechanics and controls were 47.27±9.99 years and 48.94±10.34 years, respectively. The prevalence of elevated serum cadmium was significantly higher in the automobile mechanics (25.9% vs 7.9%; p = <0.001). The significant cardiovascular risk factors in the automobile mechanics vs controls were elevated total cholesterol (32.1% vs 18.5%; p = 0.017), hyperuricemia (20.4% vs 1.2%; p = <0.001), elevated blood glucose (16.0% vs 4.9% p = 0.013); and alcohol use (55.1% vs 30.0%; p = 0.001). Among the automobile mechanics, there were significant positive correlations between serum cadmium, atherogenic index of plasma (AIP) (p = 0.024; r = 0.382) and triglyceride (p = 0.020; r = 0.391). Significant positive correlation was found between serum lead and neutrophil gelatinase associated lipocalin (NGAL) (p = <0.001; r = 0.329). There were significant positive correlation between serum cadmium level, AIP (p = 0.016; r = 0.373) and TG (p = 0.004; r = 0.439); between serum lead and NGAL in all the study participants (p = 0.005; r = 0.206).

Conclusion
Automobile mechanics have notable exposure to heavy metals and a higher prevalence of some cardiovascular risk factors. Health education and sensitisation as well as policies that would regulate exposure of persons to heavy metals should be implemented in Nigeria.
Safety and function of programmable ventriculo-peritoneal shunt valves: An in vitro 7 Tesla magnetic resonance imaging study
Authors: Chen Bixia , Dammann Philipp , Jabbarli Ramazan , Sure Ulrich , Quick Harald H. , Kraff Oliver , Wrede Karsten H. 
Published: October 2023

Objective
The quantity of ultra-high field MRI neuroimaging studies has rapidly increased. This study tests function, safety, and image artifacts of two frequently implanted programmable ventriculo-peritoneal (VP) shunt valves in a 7T MRI system.

Methods
All tests were performed using a whole-body 7T MRI system. Three proGAV 2.0 and 3 CODMAN CERTAS® Plus programmable VP-shunt valves were tested in three steps. 1) Deflection angle tests close to the bore opening at the location of a static magnetic field gradient of 3–5 T/m. 2) Valves were fixed on a spherical phantom in 3 positions (a. lateral, b. cranial, c. cranial with 22.5° tilt anteriorly) and assessed for keeping the programmed pressure setting and reprogrammability. 3) Valves were fixed on the phantom and positioned lateral in a radiofrequency head coil. MRI scans were performed for both models, including MPRAGE, GRE and SE sequences.

Results
Deflection angles were moderate (13°, 14°, 13°) for the proGAV valves and close to critical (43°, 43°, 41°) for the CODMAN valves at the test location. Taking a scaling factor of 2–3 for the maximum spatial magnetic field gradient accessible to a patient within the magnet bore into account renders both valves MR unsafe regarding ferromagnetic attraction. The proGAV valves kept the pressure settings in all positions and were reprogrammable in positions a. and b. In position c., reprogrammability was lost. The CODMAN valves changed their pressure setting and reprogrammability was lost in all positions. MR image signal homogeneity was unaltered in the phantom center, artifacts limit the assessability of structures in close vicinity to the valves.

Conclusion
Both tested programmable VP-shunt valves are MR unsafe for 7T systems. Novel programming mechanisms using permanent magnets with sufficient magnetic coercivity or magnet-free mechanisms may allow the development of programmable VP-shunt valves that are conditional for 7T MR systems.
¡A la Plaza del Progreso! La dimensión espacial del proyecto utópico del librepensamiento en Madrid, 1901-1931.
Authors: Anchorena Morales Oscar 
Published: October 2023

El movimiento anticlerical conformó un proyecto de sociedad nueva opuesta a la sociedad católica de la Restauración y una idea de hombre nuevo, al que ofrecía un modo de vida y una cosmovisión radicalmente diferentes y que abarcaba todas las etapas y aspectos de la vida. Este texto parte de la hipótesis de que el anticlericalismo restauracionista puede considerarse un proyecto utópico, articulado en un mundo nuevo, un horizonte de esperanza y una dimensión holística de la vida. Aquí se analizará la dimensión espacial de esta utopía. El intento de nueva sociedad comportó la creación de enclaves utópicos (lugares que anticipaban el nuevo mundo): de carácter permanente (escuelas y centros cívicos) o efímeros (calles, plazas, espacios de naturaleza), y otros con fuerte contenido emocional, ligados a la nostalgia de los desaparecidos o las derrotas pasadas (estatuas, cementerio). En dichos espacios se socializaron los cientos de personas participantes en el proyecto utópico librepensador.
Refractory Pediatric Fibrostenotic Eosinophilic Esophagitis Treated With Dupilumab
Authors: Gangadharan Nambiar Gopinathan , Rahhal Riad , Davis Benjamin P. , Xiong Yiqin , Cheung Donna 
Published: October 2023

ABSTRACT
Eosinophilic esophagitis (EoE) is a progressive inflammatory disease of the esophagus. Untreated or uncontrolled disease over time can lead to the development of fibrosis and formation of strictures. Once the patient develops strictures, it is difficult to treat with the available medical therapies and will often require esophageal dilations. The Food and Drug Administration recently approved dupilumab for the treatment of EoE in patients older than 12 years. The clinical trials excluded patients with esophageal strictures. We describe a case of EoE with fibrostenotic stricture who had stricture resolution while on dupilumab therapy.
Clean preparation of rutile from Ti-containing mixed molten slag by CO2 oxidation
Authors: Han Jiqing , Feng Qiuping , Zhang Li 
Published: October 2023

Abstract
The effects of SiO2 and CO2 on the crystallization action of Ti-containing mixed molten slag (molten Ti-containing blast furnace slag and molten Ti slag) were discussed by thermodynamic calculation and specific experiments. The results of thermodynamic calculation indicated that the increase of SiO2 addition mass and CO2 oxidation time can promote the transformation of anosovite and sphene to rutile. The experiment results showed that the phase composition of modification slag was only rutile under the SiO2 addition mass of 110 g and the CO2 oxidation time of 180 s. Moreover, the formation theory of rutile was investigated. Using CO2 as an oxidizing gas can not only prepare rutile but also achieve carbon neutrality, which is a clean preparation method.
Analysis of clinical characteristics in proximal and distal reflux monitoring among patients with gastroesophageal reflux disease
Authors: Wang Ping , Yu Jie , Heng Bing-Lin , Chen Yan , Guo Hong , Zhang Ying-Jian 
Published: October 2023

Abstract
The purpose of this study was to examine the characteristics of proximal and distal gastroesophageal reflux in patients with gastroesophageal reflux disorder and analyze their clinical symptoms. A total of 67 patients with typical esophageal symptoms were selected for this study. All participants completed the reflux disease questionnaire and a questionnaire survey of extraesophageal symptoms. Diagnosis was made using a 24-h impedance-pH detection and proton pump inhibitor. The results showed that the proximal reflux group had a higher number of acid reflux episodes compared to the distal reflux group (P < 0.05). Similarly, the proximal reflux group also had a higher number of gas reflux episodes compared to the distal reflux group (P < 0.05). On the other hand, the distal reflux group had a higher number of mixed reflux episodes compared to the proximal reflux group (P < 0.05). These differences were statistically significant. This study revealed that acid reflux and gas reflux were more predominant in the proximal reflux group, while mixed reflux was more predominant in the distal reflux group.
Real-time monitoring of recombinant GFP expression in single-cell Komagataella phaffii through filamentous pelletization technology
Authors: Zheng Xiao , Cong Wenjie , Zhou Hualan , Zhang Jianguo 
Published: October 2023

Abstract

Komagataella phaffii is an important cell factory for recombinant protein production under methanol induction. Tracking of recombinant protein expression by single K. phaffii cell is a hot topic to identify the variation of expression level in submerge cultivation system. In this study, a platform system harnessing Aspergillus niger pellets for K. phaffii cell immobilization in fabricated glass plate was developed to measure the green fluorescent protein (GFP) expression of single cell using fluorescence microscope. This system was optimized through pellets preparation, K. phaffii cell absorption, inducer comparison, methanol concentration, flow velocity of medium, and obtaining a successful platform to track GFP expression of single K. phaffii cell. This system provided an on-line analytical technology to discover the heterogeneous capability of various K. phaffii cells.
Diagnostic Accuracy of Saliva for Molecular Detection of SARS CoV-2 for Diagnosis of COVID 19: a Comparative Study
Authors: Tripathi Purti C. , Suryawanshi Rahul Kumar , Upadhyay Ritesh , Singh Himanshu 
Published: October 2023

Throat swab, Nasal swab, Nasopharyngeal swab, Bronchoalveolar lavage fluid and Endotracheal aspirate are the recommended samples by Indian Council of Medical Research for molecular detection of SARS-CoV-2. Saliva specimen is less invasive, can be collected by oneself thus minimizing the risk to the healthcare workers to SARS-CoV-2 exposure. The present study was aimed to evaluate better possible sample collection method among nasal swab, Throat swab and saliva samples of patients for precise COVID-19 diagnosis. A prospective study conducted for diagnosis of COVID-19 samples. three type of samples Nasal and Throat swab and saliva collected for COVID-19 diagnosis. If sample was found positive then Throat and nasal swabs were collected every alternative day while saliva collected every day for COVID-19 diagnosis by RT-PCR. 172 samples of patients were found to be positive for COVID-19. 103 (59.88 %) males and 69 (40.11 %) were females. Throat and Nasal swabs were collected every alternative day. Nasal swab was the best method of sample collection and gave most effective results followed by throat swab in comparison with the saliva sample. Saliva specimen showed positivity only for upto 3 days, while TS and NS specimens showed higher positivity in comparison with saliva specimens for upto 7 days. Further research on usefulness of less invasive saliva specimen is required.
Study of convergence speed of chaotic particle swarm optimization algorithm
Authors: Obbu Bhanu Sekhar , Jabeen Zmrooda 
Published: October 2023

AbstractThis study introduces the Chaotic Particle Swarm Optimization as an innovative variant of the traditional particle swarm optimization algorithm, addressing the issue of particle swarm optimization getting trapped in local minima with a low convergence characteristic during later iterations. Chaotic particle swarm optimization incorporates principles from chaos theory to enhance the swarm's exploration and exploitation capabilities. By introducing controlled chaotic behavior, particles exhibit more diverse and unpredictable movements in the search space, leading to improved global convergence and escape from local minima. The proposed method has been implemented and evaluated on benchmark problems to assess its effectiveness. The integration of chaos theory with particle swarm optimization offers promising opportunities for developing robust and efficient optimization techniques suitable for complex and dynamic problem domains in various real-world applications.
Occupational health and safety measures in pandemic conditions: COVID-19 practice
Authors: ACAR Hafiz Hulusi , ÜÇÜNCÜ Kemal 
Published: October 2023

The coronavirus disease (COVID-19) first appeared in China and spread globally in a short time. It was declared a pandemic by the World Health Organization (WHO) on March 11, 2020. Pandemics are a human problem. Due to the risk posed by COVID-19 on human health, all production and service workplaces around the world have slowed down their activities. These developments have caused significant labor and production losses. The most effective and practical way to prevent the transmission of the coronavirus; although there are physical distance, personal hygiene and mask applications, these do not constitute a definitive solution. Governments, organizations, employers and workers are facing important challenges to combat the COVID-19 pandemic and protect safety and health in the workplace. Unsafe workplace conditions and inappropriate working principles lead to significant health risks in the workplace. COVID-19 causes negative effects in all areas where people are present, such as health, social, economic, education, construction, manufacturing, transportation and trade. In this study, protective measures that can be taken are evaluated by reviewing the literature on the negative effects of COVID-19 on human health and therefore on workforce loss.
In addition to additional safety measures in the prevention of COVID-19, basic occupational health and safety (OHS) control methods were evaluated in the following order: (1) elimination / substitution, (2) engineering controls, (3) organizational controls, and (4) personal protective equipment (PPE). In addition to the protection of health, due to the effective safety measures, the stress caused by COVID-19 will decrease in people, so comfort in their social lives and productivity in their work lives will be increased. Therefore, governments, employers and workers' organizations have to form a joint organization with universities and health institutions.
The use of Cytoflavin in the post-withdrawal period in patients with alcohol dependence
Authors: Vostrikov Viktor V. 
Published: October 2023

BACKGROUND: The issues of therapy of dependence on psychoactive substances remain relevant at present, focusing on the prevention, treatment, and rehabilitation of these patients in the first place.
AIM: To evaluate the effectiveness of a course of Cytoflavin in patients with alcohol dependency during the post-abstinence period.
MATERIALS AND METHODS: An open, double-blind, placebo-controlled clinical study of the antioxidant Cytoflavin (10 mL/day, 5 days) effectiveness to correct emotional and motivational disorders after the treatment of alcohol withdrawal syndrome was performed in 30 patients with alcohol dependency. Anamnestic information, the clinical picture of the disease, and psychological tests the Holmes and Rage method (the degree of stress tolerance and social adaptation) and alcohol consumption motivation test (ACMT) were used to verify alcohol dependency. Before and after Cytoflavin treatment, the psychological indicators and complaints were recorded. According to the alcohol intake questionnaire, the psychological state of the patients was assessed based on a package of standard psychological tests, including the Wasserman test (level of neuroticism), Spielberger test (level of anxiety), Hamilton test (level of depression), SAN test (self-assessment of well-being, activity, and mood), and degree of craving for alcohol. For pairwise conjugated variants, the significance of differences was determined using the Students t-test; statistical analysis was performed using the standard Statistica for Windows software package.
RESULTS: In general, the course use of Cytoflavin treatment improved clinical and psychological parameters in patients with alcohol dependency in the post-abstinence period.
CONCLUSION: It is concluded that the use of the drug as a component of a comprehensive therapeutic program for alcohol dependency is highly promising.
Dental bicortical basal implant in anterior maxillary region with immediate loading in a patient of diabetic profile – A case study
Authors: Gupta Shubham kr. , Kumar Sourya 
Published: October 2023

Anterior maxilla continues to present with height risk for aesthetic failure, and as a result their is a clear need modifications that would allow for natural looking restorations that are harmonious with the rest of the mouth.To aim of this study was to evaluate the results of single tooth implant treatment in diabetic patient where the teeth have been lost as a result of trauma. Bicortical basal implant for rehabilitation of mouth is gaining popularity and emerging as a gold stranded technique in recent times. This approach help in improvising the patient aesthetic for a longer duration and provide a permanent solution. Bicortical screw are implanted in heavily corticated bone (basal bone) and is less vulnerable to infection and failure. In patients with diabetic history convention dental implants is generally contraindicated and has high failure rate. To overcome this and provide a better solution need of alternative treatments has arisen. In our study of a case report, we used bicortical dental implant for replacing the missing maxillary anterior tooth with fixed prosthetic. Interesting, though, the patients had diabetes. We found positive out come with favourable prognosis. No any significant complications were noticed and implant was successful. A Retrospective studies of various published literature and observation of our patient for a period of 12 month. We conclude that bicortical dental implants with immediate loading may be used for rehabilitating mouth in diabetes patient after evaluation of various factors such as, blood sugar levels, Cost, time and preference of patient.
ENSAYO SOBRE TIPOLOGÍA DE SUELOS COLOMBIANOS - ÉNFASIS EN GÉNESIS Y ASPECTOS AMBIENTALES
Authors: Malagón Castro Dimas 
Published: October 2023

Colombia presenta una muy amplia diversidad de suelos. Acá se tipifican aquellos que, por su grado de evolución, representan las condiciones ecológicas dominantes de las regiones naturales continentales del país. No se comenta la génesis de los Entisoles e Inceptisoles, ubicuos en todo el territorio nacional.
Inicialmente se discute el marco conceptual para el entendimiento integral de los suelos del país, en función de los factores ambientales y de los procesos evolutivos resultantes de su acción; posteriormente se tipifican por regiones y, en la parte final, se analizan, mediante índices de evolución para establecer sus relaciones ambientales en las diferentes regiones naturales de Colombia.
Gerakan Peduli Pendidikan Berbasis Komunitas (Studi Kasus Pada Komunitas Peduli Bergerak)
Authors: Rizki Syakila Fatkhia , Nugraheni Chomisah , Fatichah Hidayatul , Anggraeni Nur 
Published: October 2023

<em><span>Kualitas pendidikan di Indonesia masih rendah. Maka dari itu, terbentuk sebuah komunitas yang dibentuk oleh generasi muda bernama Komunitas Peduli Bergerak. Tujuan penelitian ini adalah untuk mendeskripsikan komunitas peduli bergerak sebagai wujud gerakan kemanusiaan di bidang pendidikan. Penelitian ini merupakan penelitian deskriptif dengan pendekatan kualitatif. Subjek dari penelitian ini adalah komunitas peduli bergerak, sementara itu metode yang digunakan dalam penelitian ini adalah menggunakan observasi, wawancara dan dokumentasi, hasil dari penelitian ini adalah komunitas peduli bergerak sebagai komunitas peduli pendidikan yang bertujuan untuk perbaikan dan peningkatkan kualitas pendidikan dengan memperhatikan pendidikan Usia Dini dan optimalisasi metode pembelajaran di lingkup wilayah daerah binaan</span></em>
A New Intelligent Model Selection Approach
Authors: BAL CAGATAY , ALADAG Cagdas Hakan 
Published: October 2023

Abstract
Modelling is a common subject in terms of application areas throughout many scientific fields such as statistics, mathematic, machine learning, artificial intelligence, deep learning, engineering, bioinformatic and so on. This interdisciplinary attribute nudge modelling into creating a simple representability of its results. The process is made by performance measures to show how well or worse the results of the model. Performance measures can be a single scalar, ratio, vector, diagram or even much complex indicators. Performances are actually models' identities and measures are the identifiers of these models. Therefore, measuring the performance of a model is very crucial step and choosing the most proper measure directly effects the identification of related model. Performance measuring can also be used for the selection of the best model among them. There are various performance criteria in the literature to determine the best model. On the other hand, it is very difficult to say which performance criterion is better according to the analysis method used or the data analyzed. Therefore, how to determine the best model is a very challenging task. In this study, to deal with this challenging issue, a new intelligent model evaluation method is proposed to measure the performance of models by approaching human intelligence. Therefore, the proposed intelligent approach offers a new perspective in model evaluation.
Behavior-related visual activations in the auditory cortex of nonhuman primates
Authors: Huang Ying , Brosch Michael 
Published: October 2023

Abstract

While it is well established that sensory cortical regions traditionally thought to be unimodal can be
activated by stimuli from modalities other than the dominant one, functions of such foreign-modal
activations are still not clear. Here we show that visual activations in early auditory cortex can be
related to whether or not the monkeys engaged in audio-visual tasks, to the time when the monkeys
reacted to the visual component of such tasks, and to the correctness of the monkeys’ response to the
auditory component of such tasks. These relationships between visual activations and behavior
suggest that auditory cortex can be recruited for visually-guided behavior and that visual activations
can prime auditory cortex such that it is prepared for processing future sounds. Our study thus
provides evidence that foreign-modal activations in sensory cortex can contribute to a subject’s ability
to perform tasks on stimuli from foreign and dominant modalities.