bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regularity and linear response formula of the SRB measures for solenoidal attractors
Authors: BOCKER CARLOS , BORTOLOTTI RICARDO , CASTRO ARMANDO 
Published: February 2024

AbstractWe show that a class of higher-dimensional hyperbolic endomorphisms admit absolutely continuous invariant probabilities whose densities are regular and vary differentiably with respect to the dynamical system. The maps we consider are skew-products given by
$T(x,y) = (E (x), C(x,y))$
, where E is an expanding map of
$\mathbb {T}^u$
and C is a contracting map on each fiber. If
$\inf |\!\det DT| \inf \| (D_yC)^{-1}\| ^{-2s}>1$
for some
${s<r-(({u+d})/{2}+1)}$
,
$r \geq 2$
, and T satisfies a transversality condition between overlaps of iterates of T (a condition which we prove to be
$C^r$
-generic under mild assumptions), then the SRB measure
$\mu _T$
of T is absolutely continuous and its density
$h_T$
belongs to the Sobolev space
$H^s({\mathbb {T}}^u\times {\mathbb {R}}^d)$
. When
$s> {u}/{2}$
, it is also valid that the density
$h_T$
is differentiable with respect to T. Similar results are proved for thermodynamical quantities for potentials close to the geometric potential.
Structural, lithostratigraphic and thermal features of a Permian lower crust from the Western Italian Alps (Valpelline Series, Valle d’Aosta)
Authors: Caso Fabiola , Strambini Antonella , Zucali Michele 
Published: February 2024

AbstractThe Valpelline Series (Dent-Blanche Tectonic System, Western Italian Alps) is a sector of lower continental crust, which consists of Permian migmatitic metapelite with different mineral assemblages (i.e., garnet-, cordierite- and orthopyroxene-bearing), minor amphibolite and marble, intruded by aplite and pegmatite. Widespread melt production in metapelite and locally in amphibolite occurred during the development of the regional foliation. The P–T conditions during migmatisation, estimated using conventional geothermobarometers, range between 800–900 °C and 0.5–0.8 GPa, with a difference of up to ∼50 °C between cordierite- and orthopyroxene-bearing migmatites, the latter reaching higher temperatures. The Valpelline Series shows rock types, metamorphic assemblages, P–T conditions and published ages of high-temperature regional metamorphism like the archetypal lower crust section of the Ivrea-Verbano Zone in the Southern Western Alps. The latter likely represents an external portion of the same extending lower crust, at the onset of the Tethyan rifting due to lithospheric extension and asthenospheric rising.
An Exploratory Study in the Portuguese Population on Writing a Suicide Note: Correlates in the Suicide Spectrum and Qualitative Analysis
Authors: Campos Rui C. , Reixa Cátia , Cardoso Paulo , Passos Bruna 
Published: February 2024

Abstract
Suicide notes are an important warning sign for suicidal behaviors. The aim of this exploratory research is (a) to contribute to understanding the place of suicide notes in the spectrum of suicidal behaviors in Portugal, and (b) to analyze the content remembered by individuals regarding a suicide note. Two complementary studies were carried out. In the first, a quantitative investigation, the statistical relationship of writing a suicide note: To the occurrence of lifetime suicide attempts, to lifetime self-harming behaviors, and to suicidal ideation in the two weeks prior to the assessment was evaluated. In the second study, a qualitative investigation, the content recalled by individuals regarding a suicide note was analyzed. In the quantitative study, 841 adults aged between 18 and 65 years, and 1,012 young adults participated. In the qualitative study, 18 young adults participated. Findings of the quantitative study reveal that writing a suicide note significantly related to the lifetime presence of a suicide attempt and to self-harming behaviors and to suicidal ideation in the two weeks prior to the assessment. Findings of the qualitative study suggest that individuals who have written suicide notes exhibit a significant self-oriented focus, yet they also demonstrate a strong sense of concern for the survivors.
Simulation-based nozzle density optimization for maximized efficacy of a machine vision–based weed control system for applications in turfgrass settings
Authors: Petelewicz Paweł , Zhou Qiyu , Schiavon Marco , MacDonald Gregory E. , Schumann Arnold W. , Boyd Nathan S. 
Published: February 2024

Abstract
Targeted spraying application technologies have the capacity to drastically reduce herbicide inputs, but to be successful, the performance of both machine vision–based weed detection and actuator efficiency needs to be optimized. This study assessed (1) the performance of spotted spurge recognition in ‘Latitude 36’ bermudagrass turf canopy using the You Only Look Once (YOLOv3) real-time multiobject detection algorithm and (2) the impact of various nozzle densities on model efficiency and projected herbicide reduction under simulated conditions. The YOLOv3 model was trained and validated with a data set of 1,191 images. The simulation design consisted of four grid matrix regimes (3 × 3, 6 × 6, 12 × 12, and 24 × 24), which would then correspond to 3, 6, 12, and 24 nonoverlapping nozzles, respectively, covering a 50-cm-wide band. Simulated efficiency testing was conducted using 50 images containing predictions (labels) generated with the trained YOLO model and by applying each of the grid matrixes to individual images. The model resulted in prediction accuracy of an F1 score of 0.62, precision of 0.65, and a recall value of 0.60. Increased nozzle density (from 3 to 12) improved actuator precision and predicted herbicide-use efficiency with a reduction in the false hits ratio from ∼30% to 5%. The area required to ensure herbicide deposition to all spotted spurge detected within images was reduced to 18%, resulting in ∼80% herbicide savings compared to broadcast application. Slightly greater precision was predicted with 24 nozzles but was not statistically different from the 12-nozzle scenario. Using this turf/weed model as a basis, optimal actuator efficacy and herbicide savings would occur by increasing nozzle density from 1 to 12 nozzles within the context of a single band.
Pathogenic NLRP3 mutants form constitutively active inflammasomes resulting in immune-metabolic limitation of IL-1β production
Authors: Molina-López Cristina , Hurtado-Navarro Laura , García Carlos J. , Angosto-Bazarra Diego , Vallejo Fernando , Tapia-Abellán Ana , Marques-Soares Joana R. , Vargas Carmen , Bujan-Rivas Segundo , Tomás-Barberán Francisco A. , Arostegui Juan I. , Pelegrin Pablo 
Published: February 2024

AbstractCryopyrin-associated periodic syndrome (CAPS) is an autoinflammatory condition resulting from monoallelic NLRP3 variants that facilitate IL-1β production. Although these are gain-of-function variants characterized by hypersensitivity to cell priming, patients with CAPS and animal models of the disease may present inflammatory flares without identifiable external triggers. Here we find that CAPS-associated NLRP3 variants are forming constitutively active inflammasome, which induce increased basal cleavage of gasdermin D, IL-18 release and pyroptosis, with a concurrent basal pro-inflammatory gene expression signature, including the induction of nuclear receptors 4 A. The constitutively active NLRP3-inflammasome of CAPS is responsive to the selective NLRP3 inhibitor MCC950 and its activation is regulated by deubiquitination. Despite their preactivated state, the CAPS inflammasomes are responsive to activation of the NF-κB pathway. NLRP3-inflammasomes with CAPS-associated variants affect the immunometabolism of the myeloid compartment, leading to disruptions in lipids and amino acid pathways and impaired glycolysis, limiting IL-1β production. In summary, NLRP3 variants causing CAPS form a constitutively active inflammasome inducing pyroptosis and IL-18 release without cell priming, which enables the host’s innate defence against pathogens while also limiting IL-1β–dependent inflammatory episodes through immunometabolism modulation.
A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
Authors: Hai Ling , Hoffmann Dirk C. , Wagener Robin J. , Azorin Daniel D. , Hausmann David , Xie Ruifan , Huppertz Magnus-Carsten , Hiblot Julien , Sievers Philipp , Heuer Sophie , Ito Jakob , Cebulla Gina , Kourtesakis Alexandros , Kaulen Leon D. , Ratliff Miriam , Mandelbaum Henriette , Jung Erik , Jabali Ammar , Horschitz Sandra , Ernst Kati J. , Reibold Denise , Warnken Uwe , Venkataramani Varun , Will Rainer , Suvà Mario L. , Herold-Mende Christel , Sahm Felix , Winkler Frank , Schlesner Matthias , Wick Wolfgang , Kessler Tobias 
Published: February 2024

AbstractTumor microtubes (TMs) connect glioma cells to a network with considerable relevance for tumor progression and therapy resistance. However, the determination of TM-interconnectivity in individual tumors is challenging and the impact on patient survival unresolved. Here, we establish a connectivity signature from single-cell RNA-sequenced (scRNA-Seq) xenografted primary glioblastoma (GB) cells using a dye uptake methodology, and validate it with recording of cellular calcium epochs and clinical correlations. Astrocyte-like and mesenchymal-like GB cells have the highest connectivity signature scores in scRNA-sequenced patient-derived xenografts and patient samples. In large GB cohorts, TM-network connectivity correlates with the mesenchymal subtype and dismal patient survival. CHI3L1 gene expression serves as a robust molecular marker of connectivity and functionally influences TM networks. The connectivity signature allows insights into brain tumor biology, provides a proof-of-principle that tumor cell TM-connectivity is relevant for patients’ prognosis, and serves as a robust prognostic biomarker.
Intrinsic supercurrent non-reciprocity coupled to the crystal structure of a van der Waals Josephson barrier
Authors: Kim Jae-Keun , Jeon Kun-Rok , Sivakumar Pranava K. , Jeon Jaechun , Koerner Chris , Woltersdorf Georg , Parkin Stuart S. P. 
Published: February 2024

AbstractNon-reciprocal electronic transport in a spatially homogeneous system arises from the simultaneous breaking of inversion and time-reversal symmetries. Superconducting and Josephson diodes, a key ingredient for future non-dissipative quantum devices, have recently been realized. Only a few examples of a vertical superconducting diode effect have been reported and its mechanism, especially whether intrinsic or extrinsic, remains elusive. Here we demonstrate a substantial supercurrent non-reciprocity in a van der Waals vertical Josephson junction formed with a Td-WTe2 barrier and NbSe2 electrodes that clearly reflects the intrinsic crystal structure of Td-WTe2. The Josephson diode efficiency increases with the Td-WTe2 thickness up to critical thickness, and all junctions, irrespective of the barrier thickness, reveal magneto-chiral characteristics with respect to a mirror plane of Td-WTe2. Our results, together with the twist-angle-tuned magneto-chirality of a Td-WTe2 double-barrier junction, show that two-dimensional materials promise vertical Josephson diodes with high efficiency and tunability.
Logical rotation of non-separable states via uniformly self-assembled chiral superstructures
Authors: Zhang Yi-Heng , Liu Si-Jia , Chen Peng , Zhu Dong , Chen Wen , Ge Shi-Jun , Wang Yu , Zhang Zhi-Feng , Lu Yan-Qing 
Published: February 2024

AbstractThe next generation of high-capacity, multi-task optical informatics requires sophisticated manipulation of multiple degrees of freedom (DoFs) of light, especially when they are coupled in a non-separable way. Vector beam, as a typical non-separable state between the spin and orbital angular momentum DoFs, mathematically akin to entangled qubits, has inspired multifarious theories and applications in both quantum and classical regimes. Although qubit rotation is a vital and ubiquitous operation in quantum informatics, its classical analogue is rarely studied. Here, we demonstrate the logical rotation of vectorial non-separable states via the uniform self-assembled chiral superstructures, with favorable controllability, high compactness and exemption from formidable alignment. Photonic band engineering of such 1D chiral photonic crystal renders the incident-angle-dependent evolution of the spatially-variant polarizations. The logical rotation angle of a non-separable state can be tuned in a wide range over 4π by this single homogeneous device, flexibly providing a set of distinguished logic gates. Potential applications, including angular motion tracking and proof-of-principle logic network, are demonstrated by specific configuration. This work brings important insight into soft matter photonics and present an elegant strategy to harness high-dimensional photonic states.
Petal abscission is promoted by jasmonic acid-induced autophagy at Arabidopsis petal bases
Authors: Furuta Yuki , Yamamoto Haruka , Hirakawa Takeshi , Uemura Akira , Pelayo Margaret Anne , Iimura Hideaki , Katagiri Naoya , Takeda-Kamiya Noriko , Kumaishi Kie , Shirakawa Makoto , Ishiguro Sumie , Ichihashi Yasunori , Suzuki Takamasa , Goh Tatsuaki , Toyooka Kiminori , Ito Toshiro , Yamaguchi Nobutoshi 
Published: February 2024

AbstractIn angiosperms, the transition from floral-organ maintenance to abscission determines reproductive success and seed dispersion. For petal abscission, cell-fate decisions specifically at the petal-cell base are more important than organ-level senescence or cell death in petals. However, how this transition is regulated remains unclear. Here, we identify a jasmonic acid (JA)-regulated chromatin-state switch at the base of Arabidopsis petals that directs local cell-fate determination via autophagy. During petal maintenance, co-repressors of JA signaling accumulate at the base of petals to block MYC activity, leading to lower levels of ROS. JA acts as an airborne signaling molecule transmitted from stamens to petals, accumulating primarily in petal bases to trigger chromatin remodeling. This allows MYC transcription factors to promote chromatin accessibility for downstream targets, including NAC DOMAIN-CONTAINING PROTEIN102 (ANAC102). ANAC102 accumulates specifically at the petal base prior to abscission and triggers ROS accumulation and cell death via AUTOPHAGY-RELATED GENEs induction. Developmentally induced autophagy at the petal base causes maturation, vacuolar delivery, and breakdown of autophagosomes for terminal cell differentiation. Dynamic changes in vesicles and cytoplasmic components in the vacuole occur in many plants, suggesting JA–NAC-mediated local cell-fate determination by autophagy may be conserved in angiosperms.
Relaxation of mitochondrial hyperfusion in the diabetic retina via N6-furfuryladenosine confers neuroprotection regardless of glycaemic status
Authors: Anderson Aidan , Alfahad Nada , Wimalachandra Dulani , Bouzinab Kaouthar , Rudzinska Paula , Wood Heather , Fazey Isabel , Xu Heping , Lyons Timothy J. , Barnes Nicholas M. , Narendran Parth , Lord Janet M. , Rauz Saaeha , Ganley Ian G. , Curtis Tim M. , Wallace Graham R. , Hombrebueno Jose R. 
Published: February 2024

AbstractThe recovery of mitochondrial quality control (MQC) may bring innovative solutions for neuroprotection, while imposing a significant challenge given the need of holistic approaches to restore mitochondrial dynamics (fusion/fission) and turnover (mitophagy and biogenesis). In diabetic retinopathy, this is compounded by our lack of understanding of human retinal neurodegeneration, but also how MQC processes interact during disease progression. Here, we show that mitochondria hyperfusion is characteristic of retinal neurodegeneration in human and murine diabetes, blunting the homeostatic turnover of mitochondria and causing metabolic and neuro-inflammatory stress. By mimicking this mitochondrial remodelling in vitro, we ascertain that N6-furfuryladenosine enhances mitochondrial turnover and bioenergetics by relaxing hyperfusion in a controlled fashion. Oral administration of N6-furfuryladenosine enhances mitochondrial turnover in the diabetic mouse retina (Ins2Akita males), improving clinical correlates and conferring neuroprotection regardless of glycaemic status. Our findings provide translational insights for neuroprotection in the diabetic retina through the holistic recovery of MQC.
Small-pore hydridic frameworks store densely packed hydrogen
Authors: Oh Hyunchul , Tumanov Nikolay , Ban Voraksmy , Li Xiao , Richter Bo , Hudson Matthew R. , Brown Craig M. , Iles Gail N. , Wallacher Dirk , Jorgensen Scott W. , Daemen Luke , Balderas-Xicohténcatl Rafael , Cheng Yongqiang , Ramirez-Cuesta Anibal J. , Heere Michael , Posada-Pérez Sergio , Hautier Geoffroy , Hirscher Michael , Jensen Torben R. , Filinchuk Yaroslav 
Published: February 2024

AbstractNanoporous materials have attracted great attention for gas storage, but achieving high volumetric storage capacity remains a challenge. Here, by using neutron powder diffraction, volumetric gas adsorption, inelastic neutron scattering and first-principles calculations, we investigate a magnesium borohydride framework that has small pores and a partially negatively charged non-flat interior for hydrogen and nitrogen uptake. Hydrogen and nitrogen occupy distinctly different adsorption sites in the pores, with very different limiting capacities of 2.33 H2 and 0.66 N2 per Mg(BH4)2. Molecular hydrogen is packed extremely densely, with about twice the density of liquid hydrogen (144 g H2 per litre of pore volume). We found a penta-dihydrogen cluster where H2 molecules in one position have rotational freedom, whereas H2 molecules in another position have a well-defined orientation and a directional interaction with the framework. This study reveals that densely packed hydrogen can be stabilized in small-pore materials at ambient pressures.
COBRA improves the completeness and contiguity of viral genomes assembled from metagenomes
Authors: Chen LinXing , Banfield Jillian F. 
Published: February 2024

AbstractViruses are often studied using metagenome-assembled sequences, but genome incompleteness hampers comprehensive and accurate analyses. Contig Overlap Based Re-Assembly (COBRA) resolves assembly breakpoints based on the de Bruijn graph and joins contigs. Here we benchmarked COBRA using ocean and soil viral datasets. COBRA accurately joined the assembled sequences and achieved notably higher genome accuracy than binning tools. From 231 published freshwater metagenomes, we obtained 7,334 bacteriophage clusters, ~83% of which represent new phage species. Notably, ~70% of these were circular, compared with 34% before COBRA analyses. We expanded sampling of huge phages (≥200 kbp), the largest of which was curated to completion (717 kbp). Improved phage genomes from Rotsee Lake provided context for metatranscriptomic data and indicated the in situ activity of huge phages, whiB-encoding phages and cysC- and cysH-encoding phages. COBRA improves viral genome assembly contiguity and completeness, thus the accuracy and reliability of analyses of gene content, diversity and evolution.
Aula Verde (tree room) as a link between art and science to raise public awareness of nature-based solutions
Authors: Conte A. , Pace R. , Li Q. , Carloni S. , Boetzkes A. , Passatore L. 
Published: February 2024

AbstractNature-based solutions inherently require a multifaceted perspective that encompasses diverse fields. The aim of this project is to develop more effective nature-based solutions, climate action and environmental awareness by breaking down boundaries between disciplines and fostering a co-creative process. Concepts of ecology and urban forestry were combined with the research on political ecology, environmental humanities, land art, regenerative art, performing art, participatory art, and more-than-human art. This process resulted in the creation of Aula Verde Aniene. It is located in an urban park in Rome and consists of a stand of trees arranged in circles with a specific design to give the perception of being in an outdoor vegetated room. The project activities involved community participation through art performances and citizen science initiatives. Regulating and cultural ecosystem services of Aula Verde were assessed using i-Tree Eco software and citizens’ surveys. Beyond numerical descriptions of ecosystem services, the manuscript introduces shinrin-yoku as a practice to raise awareness of nature. The distinctive approach here described contributed to convey a sense of belonging to the ecosystem to citizens. The project framework and study findings have been developed to formulate policy recommendations and disseminate a format that can be adapted to diverse locations.
Reproducing burrows in modelled sedimentary strata
Authors: Eltom Hassan 
Published: February 2024

AbstractStudying bioturbated sedimentary strata is crucial; however, sampling these strata poses notable challenges. Modelling these strata has emerged as a promising solution to bridge this gap. This study introduces a workflow to model burrows utilizing the multipoint statistics (MPS) method. A key step in MPS modelling is the use of training images, and this study describes a process to create them using CT scans of rock samples contain burrows. These scans give a 3D visual representation of burrows in actual rock record. The process involves selecting suitable rock samples, CT scanning them, importing and processing the scans in Petrel™, and then transforming the scan data into training images which can be used for MPS modelling. The MPS models allow for precise replication of burrows, variations in their size and percentage, and modeling properties like porosity and permeability. This enables a more detailed analysis, paving the way for further advancements in understanding and simulating the geological implications of burrows. To guarantee reproducibility, this study has precisely documented the workflow with video guidance and provided the necessary data. This comprehensive documentation aims to encourage the broader adoption of MPS modelling for bioturbated strata, setting the stage for further advancements in the field.