bluuebunny/crossref_metadata_2025_split huggingface dataset:
Population synthesis of Be X-ray binaries: metallicity dependence of total X-ray outputs
Authors: Liu Boyuan , Sartorio Nina S , Izzard Robert G , Fialkov Anastasia 
Published: November 2023

ABSTRACT
X-ray binaries (XRBs) are thought to regulate cosmic thermal and ionization histories during the Epoch of Reionization and Cosmic Dawn (z ∼ 5–30). Theoretical predictions of the X-ray emission from XRBs are important for modelling such early cosmic evolution. Nevertheless, the contribution from Be-XRBs, powered by accretion of compact objects from decretion discs around rapidly rotating O/B stars, has not been investigated systematically. Be-XRBs are the largest class of high-mass XRBs (HMXBs) identified in local observations and are expected to play even more important roles in metal-poor environments at high redshifts. In light of this, we build a physically motivated model for Be-XRBs based on recent hydrodynamic simulations and observations of decretion discs. Our model is able to reproduce the observed population of Be-XRBs in the Small Magellanic Cloud with appropriate initial conditions and binary stellar evolution parameters. We derive the X-ray output from Be-XRBs as a function of metallicity in the (absolute) metallicity range Z ∈ [10−4, 0.03] with a large suite of binary population synthesis (BPS) simulations. The simulated Be-XRBs can explain a non-negligible fraction ($\gtrsim 30{{\ \rm per\ cent}}$) of the total X-ray output from HMXBs observed in nearby galaxies for Z ∼ 0.0003–0.02. The X-ray luminosity per unit star formation rate from Be-XRBs in our fiducial model increases by a factor of ∼8 from Z = 0.02 to Z = 0.0003, which is similar to the trend seen in observations of all types of HMXBs. We conclude that Be-XRBs are potentially important X-ray sources that deserve greater attention in BPS of XRBs.
Are the ultra-high-redshift galaxies at z &gt; 10 surprising in the context of standard galaxy formation models?
Authors: Yung L Y Aaron , Somerville Rachel S , Finkelstein Steven L , Wilkins Stephen M , Gardner Jonathan P 
Published: November 2023

ABSTRACT
A substantial number of ultra-high redshift (8 ≲ z ≲ 17) galaxy candidates have been detected with JWST, posing the question: Are these observational results surprising in the context of current galaxy formation models? We address this question using the well-established Santa Cruz semi-analytic models, implemented within merger trees from the new suite of cosmological N-body simulations gureft, which were carefully designed for ultra-high redshift studies. Using our fiducial models calibrated at z = 0, we present predictions for stellar mass functions, rest-frame UV luminosity functions, and various scaling relations. We find that our (dust-free) models predict galaxy number densities at z ∼ 11 (z ∼ 13) that are an order of magnitude (a factor of ∼30) lower than the observational estimates. We estimate the uncertainty in the observed number densities due to cosmic variance, and find that it leads to a fractional error of ∼20–30 per cent at z = 11 (∼30–80 per cent at z = 14) for a 100 arcmin2 field. We explore which processes in our models are most likely to be rate-limiting for the formation of luminous galaxies at these early epochs, considering the halo formation rate, gas cooling, star formation, and stellar feedback, and conclude that it is mainly efficient stellar-driven winds. We find that a modest boost of a factor of ∼4 to the UV luminosities, which could arise from a top-heavy stellar initial mass function, would bring our current models into agreement with the observations. Adding a stochastic component to the UV luminosity can also reconcile our results with the observations.
Constraints on redshifts of blazars from extragalactic background light attenuation using Fermi-LAT data
Authors: Domínguez Alberto , Láinez María , Paliya Vaidehi S , Álvarez-Crespo Nuria , Ajello Marco , Finke Justin , Nievas-Rosillo Mireia , Contreras Jose Luis , Desai Abhishek 
Published: November 2023

ABSTRACT
The extragalactic high-energy γ-ray sky is dominated by blazars, which are active galactic nuclei with their jets pointing towards us. Distance measurements are of fundamental importance yet for some of these sources are challenging because any spectral signature from the host galaxy may be outshone by the non-thermal emission from the jet. In this paper, we present a method to constrain redshifts for these sources that relies only on data from the Large Area Telescope on board the Fermi Gamma-ray Space Telescope. This method takes advantage of the signatures that the pair-production interaction between photons with energies larger than approximately 10 GeV and the extragalactic background light leaves on γ-ray spectra. We find upper limits for the distances of 303 γ-ray blazars, classified as 157 BL Lacertae objects, 145 of uncertain class, and 1 flat-spectrum-radio quasar, whose redshifts are otherwise unknown. These derivations can be useful for planning observations with imaging atmospheric Cherenkov telescopes and also for testing theories of supermassive black hole evolution. Our results are applied to estimate the detectability of these blazars with the future Cherenkov Telescope Array, finding that at least 21 of them could be studied in a reasonable exposure of 20 h.
WInDI: a Warp-Induced Dust Instability in protoplanetary discs
Authors: Aly Hossam , Nealon Rebecca , Gonzalez Jean-François 
Published: November 2023

ABSTRACT
We identify a new dust instability that occurs in warped discs. The instability is caused by the oscillatory gas motions induced by the warp in the bending wave regime. We first demonstrate the instability using a local 1D (vertical) toy model based on the warped shearing box coordinates and investigate the effects of the warp magnitude and dust Stokes number on the growth of the instability. We then run 3D smoothed particle hydrodynamics (SPH) simulations and show that the instability is manifested globally by producing unique dust structures that do not correspond to gas pressure maxima. The 1D and SPH analysis suggest that the instability grows on dynamical time-scales and hence is potentially significant for planet formation.
The Taurid Resonant Swarm at Mercury
Authors: Christou Apostolos A , Egal Auriane , Georgakarakos Nikolaos 
Published: November 2023

ABSTRACT
It has previously been suggested that ejection and vaporization of Hermean surface material by meteoroids from comet 2P/Encke causes a seasonal enhancement in Mercury’s Ca exosphere observed by the NASA MESSENGER spacecraft in 2011-2015. The ESA/JAXA BepiColoen mission, now routeute to Mercury, will likely provide the next set of observational tests of this hypothesis after it enters orbit in late 2025. Here we study the Taurid Swarm Complex (IAU Code: STS), a population of cm-sized or larger meteoroids from Encke’s comet that encounters the Earth every 3–7 yr. Through analysis of previous observations of the STS and many-particle numerical simulations, we study the circumstances of encounters between the STS and Mercury and find that, unlike the Earth where STS encounters is observed in some years but not others, each time the STS is at perihelion it encounters Mercury on three consecutive planetary orbits. We further predict that the STS will encounter this planet during the early stages of BepiColombo’s orbital mission. The temporal flux profile during each encounter will be broad and possibly double-peaked with total number fluence 0.4×–1.7× that of the sporadic fluence for &gt;1 kg meteoroids on the sub-radiant hemisphere of the planet. The meteoroid arrival direction and sub-radiant point strongly depend on True Anomaly Angle, switching from mainly nightside to mainly dayside impacts as Mercury travels from orbital perihelion to aphelion. Our predictions may be used to create detailed models of exosphere generation by Encke stream meteoroids.
Observing network effect of shipping emissions from space: A natural experiment in the world’s busiest port
Authors: Liu Song , Li Xicheng , Li Juan , Shu Lei , Fu Tzung-May , Yang Xin , Zhu Lei 
Published: November 2023

AbstractMaritime trade and associated emissions are dynamic in nature. Although shipping emissions contribute significantly to air quality and climate change, their trade-governed dynamics remain less explored due to the lack of observational evidence. Here, we use satellite measurements to capture the redistribution of shipping nitrogen oxides (NOx) emissions from Shanghai port, the world’s busiest port, during a natural experiment posted by the localized COVID-19 lockdown in 2022. Viewing the ports as nodes in a network linked by ship journeys, we quantify a lockdown-induced −42% reduction in shipping NOx emissions for Shanghai port. We further identify an emission transfer to its neighboring connected ports, confirmed by comprehensive vessel activity observations. Our study highlights the socioeconomic drivers of shipping emissions, which may add additional layers of complexity to air quality management.
Development of DynamicMC for PHITS Monte Carlo package
Authors: Watabe Hiroshi , Sato Tatsuhiko , Yu Kwan Ngok , Zivkovic Milena , Krstic Dragana , Nikezic Dragoslav , Kim Kyeong Min , Yamaya Taiga , Kawachi Naoki , Tanaka Hiroki , Haque A K F , Islam M Rafiqul , Shahmohammadi Beni Mehrdad 
Published: November 2023

Abstract
Previously, we have developed DynamicMC for modeling relative movement of Oak Ridge National Laboratory phantom in a radiation field for the Monte Carlo N-Particle package (Health Physics. 2023,124(4):301–309). Using this software, three-dimensional dose distributions in a phantom irradiated by a certain mono-energetic (Mono E) source can be deduced through its graphical user interface. In this study, we extended DynamicMC to be used in combination with the Particle and Heavy Ion Transport code System (PHITS) by providing it with a higher flexibility for dynamic movement for an anthropomorphic phantom. For this purpose, we implemented four new functions into the software, which are (1) to generate not only Mono E sources but also those having an energy spectrum of an arbitrary radioisotope (2) to calculate the absorbed doses for several radiologically important organs (3) to automatically average the calculated absorbed doses along the path of the phantom and (4) to generate user-defined slab shielding materials. The first and third items utilize the PHITS-specific modalities named radioisotope-source and sumtally functions, respectively. The computational cost and complexity can be dramatically reduced with these features. We anticipate that the present work and the developed open-source tools will be in the interest of nuclear radiation physics community for research and teaching purposes.
Plasma and cerebrospinal fluid proteomic signatures of acutely sleep-deprived humans: an exploratory study
Authors: Vaquer-Alicea Ana , Yu Jinsheng , Liu Haiyan , Lucey Brendan P 
Published: November 2023

Abstract

Study Objectives
Acute sleep deprivation affects both central and peripheral biological processes. Prior research has mainly focused on specific proteins or biological pathways that are dysregulated in the setting of sustained wakefulness. This exploratory study aimed to provide a comprehensive view of the biological processes and proteins impacted by acute sleep deprivation in both plasma and cerebrospinal fluid (CSF).

Methods
We collected plasma and CSF from human participants during one night of sleep deprivation and controlled normal sleep conditions. One thousand and three hundred proteins were measured at hour 0 and hour 24 using a high-scale aptamer-based proteomics platform (SOMAscan) and a systematic biological database tool (Metascape) was used to reveal altered biological pathways.

Results
Acute sleep deprivation decreased the number of upregulated and downregulated biological pathways and proteins in plasma but increased upregulated and downregulated biological pathways and proteins in CSF. Predominantly affected proteins and pathways were associated with immune response, inflammation, phosphorylation, membrane signaling, cell-cell adhesion, and extracellular matrix organization.

Conclusions
The identified modifications across biofluids add to evidence that acute sleep deprivation has important impacts on biological pathways and proteins that can negatively affect human health. As a hypothesis-driving study, these findings may help with the exploration of novel mechanisms that mediate sleep loss and associated conditions, drive the discovery of new sleep loss biomarkers, and ultimately aid in the identification of new targets for intervention to human diseases.
DNA Damage Response After Treatment of Cycling and Quiescent Cord Blood Hematopoietic Stem Cells With Distinct Genotoxic Noxae
Authors: Becker Fabienne , Ouzin Meryem , Liedtke Stefanie , Raba Katharina , Kogler Gesine 
Published: November 2023

Abstract
Hematopoietic stem cells (HSC) from cord blood can be applied as an alternative to bone marrow in transplantation to treat hematological diseases. Umbilical cord blood (UCB) consists of cycling and non-cycling CD34+/CD45low cells needed for long-term and short-term engraftment. After sorting and subsequent in vitro culture, quiescent HSCs enter the cell cycle. This enables the analysis of HSCs in 2 different cell cycle stages and the comparison of their responses to different genotoxic noxae. To analyze different mechanisms of DNA damage induction in cells, 2 different genotoxins were compared: etoposide, a topoisomerase II inhibitor that targets mitosis in the S/G2-phase of the cell cycle and the alkylating nitrosamine N-Nitroso-N-methylurea (MNU), which leads to the formation of methyl DNA adducts resulting in DNA double breaks during DNA replication and persistent mutations. Cycling cells recovered after treatment even with higher concentrations of etoposide (1.5µM/ 5µM/10µM), while sorted cells treated with MNU (0.1mM/0.3mM/0.5mM/1mM/3Mm/ 5mM) recovered after treatment with the lower MNU concentrations whereas high MNU concentrations resulted in apoptosis activation. Quiescent cells were not affected by etoposide treatment showing no damage upon entry into the cell cycle. Treatment with MNU, similarly to the cycling cells, resulted in a dose-dependent cell death. In conclusion, we found that depending on the genotoxic trigger and the cycling status, CD34+cells have distinct responses to DNA damage. Cycling cells employ both DDR and apoptosis mechanisms to prevent damage accumulation. Quiescent cells predominantly undergo apoptosis upon damage, but their cell cycle status protects them from certain genotoxic insults.
Searching for Mediterranean bath sponges (Demospongiae: Dictyoceratida: Spongiidae) in the Northeast Atlantic reveals a new species: an integrative taxonomic approach
Authors: Grenier Marie , Simmler Charlotte , Chevaldonné Pierre , Callizot Noëlle , Pérez Thierry 
Published: November 2023

Abstract
Bath sponges, included in the Spongiidae (Demospongiae: Dictyoceratida), are distributed across the oceans of the world, with a greater abundance in temperate, subtropical, and tropical zones. Their harvest started during ancient times in the Mediterranean Sea, which shed light on the whole family. Most of the Mediterranean Spongiidae have been reported repeatedly from the Northeast Atlantic, notably along the Iberian peninsula. The aim of this study was to clarify the taxonomic status of these sponges after a recent sampling effort in the French Pays Basque and the Spanish Cantabria, complemented by several Mediterranean Sea stations, including the Strait of Gibraltar. An integrative taxonomic approach was adopted for the first time on a set of Spongiidae samples from the Northeast Atlantic, assessing the congruence of analyses of: (i) the morphology of the spongin skeleton; (ii) two different parts of the genome (mitochondrial and nuclear); and (iii) metabolomic fingerprints, to delimit the frontiers between species better. A new bath sponge species is described herein, and significant advances and changes are proposed for the systematics of the family.
Inequities Along the Human Immunodeficiency Virus (HIV) Pre-exposure Prophylaxis Services Continuum for Black Women in the United States, 2015–2020
Authors: Townes Ashley , Tanner Mary R. , Yu Lei , Johnson Wayne D. , Zhu Weiming , Iqbal Kashif , Dominguez Kenneth L. , Henny Kirk D. , Drezner Kate , Schumacher Christina , Bickham Jacquelyn , Elopre Latesha , Edelstein Zoe R. , Hoover Karen W. ,   the Targeted Highly Effective Interventions to Reverse the HIV Epidemic (THRIVE) Project Team*
Published: November 2023

OBJECTIVE:
To estimate the number of women who received human immunodeficiency virus (HIV) and sexually transmitted infection (STI) testing and HIV pre-exposure prophylaxis (PrEP) services by race and ethnicity in seven THRIVE (Targeted Highly Effective Interventions to Reverse the HIV Epidemic)–funded jurisdictions and to estimate associations of age and syphilis and gonorrhea diagnoses with receipt of HIV PrEP services.

METHODS:
We analyzed data collected from 2015 to 2020 in Birmingham, Alabama; Baltimore City, Maryland; Washington, DC, New Orleans, Louisiana; Brooklyn, New York; Philadelphia, Pennsylvania; and Hampton Roads, Virginia. We compared Black women and women of additional racial and ethnic groups by age, HIV status at enrollment, receipt of STI testing and test positivity, and steps in the PrEP continuum (screened, eligible, referred, linked, and prescribed). We also examined the association of age, syphilis, or gonorrhea with the following steps in the PrEP continuum: screened, referred, linked, and prescribed.

RESULTS:
Black women made up 69.2% (8,758/12,647) of women served in THRIVE. Compared with non-Black women, Black women were more likely to have a positive test result for syphilis (3.3% vs 2.1%), gonorrhea (4.9% vs 3.5%), chlamydia (5.1% vs 1.9%), or more than one STI (1.4% vs 0.3%). Among women with negative HIV test results or unknown HIV status, Black women were more likely to be screened for PrEP eligibility (88.4% vs 64.9%). Among Black women, the proportion screened for PrEP was higher among those diagnosed with syphilis (97.3%) or gonorrhea (100%) than among those without an STI (88.1% and 87.8%, respectively). Among 219 Black women who presented with syphilis, only 10 (4.6%) were prescribed PrEP; among 407 with gonorrhea, only 11 (2.7%) were prescribed PrEP.

CONCLUSION:
Although most Black women seeking services received STI testing, the proportion of Black women who were eligible for PrEP and prescribed PrEP was low. To achieve national HIV-prevention goals, it is imperative that Black women have access to PrEP information and services.
Patient Surgical Outcomes When Surgery Residents Are the Primary Surgeon by Intensity of Surgical Attending Supervision in Veterans Affairs Medical Centers
Authors: Kashner T. Michael , Greenberg Paul B. , Birnbaum Andrea D. , Byrne John M. , Sanders Karen M. , Wilson Mark A. , Bowman Marjorie A. 
Published: November 2023

Objective:
Using health records from the Department of Veterans Affairs (VA), the largest healthcare training platform in the United States, we estimated independent associations between the intensity of attending supervision of surgical residents and 30-day postoperation patient outcomes.

Background:
Academic leaders do not agree on the level of autonomy from supervision to grant surgery residents to best prepare them to enter independent practice without risking patient outcomes.

Methods:
Secondary data came from a national, systematic 1:8 sample of n = 862,425 teaching encounters where residents were listed as primary surgeon at 122 VA medical centers from July 1, 2004, through September 30, 2019. Independent associations between whether attendings had scrubbed or not scrubbed on patient 30-day all-cause mortality, complications, and 30-day readmission were estimated using generalized linear-mixed models. Estimates were tested for any residual confounding biases, robustness to different regression models, stability over time, and validated using moderator and secondary factors analyses.

Results:
After accounting for potential confounding factors, residents supervised by scrubbed attendings in 733,997 nonemergency surgery encounters had fewer deaths within 30 days of the operation by 14.2% [0.3%, 29.9%], fewer case complications by 7.9% [2.0%, 14.0%], and fewer readmissions by 17.5% [11.2%, 24.2%] than had attendings not scrubbed. Over the 15 study years, scrubbed surgery attendings may have averted an estimated 13,700 deaths, 43,600 cases with complications, and 73,800 readmissions.

Conclusions:
VA policies on attending surgeon supervision have protected patient safety while allowing residents in selected teaching encounters to have limited autonomy from supervision.
Diagnosis and management of primary heart involvement in systemic sclerosis
Authors: De Luca Giacomo , Matucci-Cerinic Marco , Mavrogeni Sophie I. 
Published: November 2023

Purpose of review
In systemic sclerosis (SSc) primary heart involvement (pHI) is frequent, even though often unrecognized due to its occult nature and to the lack of a specific diagnostic algorithm. The purpose of this review is to report the state of the art of the evidence in the current literature, as well as the overall diagnostic modalities and therapeutic strategies for primary heart involvement in SSc.

Recent findings
SSc-pHI is defined by the presence of cardiac abnormalities that are predominantly attributable to SSc rather than other causes and/or complications; it may be sub-clinical and must be confirmed through diagnostic investigations. Novel electrocardiographic analysis and cardiac magnetic resonance (CMR) with mapping techniques have been recently proposed, showing a great utility in the early identification of SSc-pHI and in the noninvasive characterization of myocardial tissue. Immunosuppressive therapy emerged as fundamental to curb myocardial inflammation, and recent preclinical and clinical data support the role of antifibrotic drugs to treat SSc-pHI.

Summary
our review will help clinicians to properly integrate the available diagnostic modalities for the assessment of SSc-pHI. The ultimate goal is to propose a feasible diagnostic algorithm for the early identification of patients with SSc-pHI, and a schematic therapeutic approach to manage SSc-pHI.