bluuebunny/crossref_metadata_2025_split huggingface dataset:
Incidental appendicectomy in pancreas transplantation: A single‐center study
Authors: Hussein Aliyah , Karydis Nikolaos , Gill‐Barman Baljit , Callaghan Chris 
Published: October 2023

AbstractBackgroundAppendicitis in pancreatic transplant recipients can be challenging to diagnose and manage. Incidental appendicectomy (IA) during pancreas transplantation obviates the risk of appendicitis but potentially at the cost of increased operating time or early post‐operative complications. This study reviewed the value of IA at a single center.MethodsThis was a retrospective study of patients who underwent a pancreas transplant in our unit from January 1st, 2012 to December 31st, 2020, with end of follow‐up on May 21st, 2023; recipients were grouped by whether or not an IA was performed during pancreas transplantation. Donor, recipient, operative, and graft outcomes were compared between the two groups. Post‐transplant complications related to appendiceal pathology (or IA) were recorded and classified.ResultsTwo hundred forty‐three patients underwent a pancreas transplant; 227 (93%) patients had an appendix in situ at transplantation, and of these 53 (23%) underwent an IA and 174 (77%) did not. There were no statistically significant differences in operative time (p = .06) or hospital stay (p = .50) between the two groups. In the IA cohort, there were no Clavien‐Dindo Grade III‐V complications relating to the appendicectomy. In those that did not undergo an IA, two patients (1%) subsequently required appendicectomy due to appendicitis. Comparison of pancreatic graft survival showed no statistically significant difference between the groups (p = .44).ConclusionsThis study suggests that IA is effective at reducing risks of post‐transplant appendiceal complications without significantly prolonging inpatient stay or impairing graft survival. These data support the consideration of undertaking an IA for all patients undergoing a pancreas transplant.
Systematic review of the role of calprotectin in cirrhosis
Authors: Fortuny Marta , Sarrias Maria‐Rosa , Torner Maria , Iborra Ignacio , Clos Ariadna , Ardèvol Alba , Bartolí Ramon , Morillas Rosa M. , Domènech Eugeni , Masnou Helena 
Published: October 2023

AbstractBackgroundCalprotectin is a calcium‐binding‐S100‐protein synthetized mainly in neutrophils which has been demonstrated to be an accurate biomarker of the presence of these cells. Gut barrier dysfunction in patients with advanced chronic liver disease (ACLD), in addition to the lack of noninvasive tools for diagnosis and prognosis of cirrhosis decompensations, has raised interest in this biomarker.AimsOur aim is to summarize the current evidence regarding the role of calprotectin in terms of its diagnostic and prognostic utility in ACLD.MethodsWe performed a systematic search (PROSPERO registration no. CRD42023389069) of original articles published without any restrictions on the publication date until January 2023 providing information about calprotectin for the prognosis or diagnosis of ACLD and its decompensations in adult patients.ResultsA total 227 articles were identified, and 26 observational studies finally met the inclusion criteria. In 14 studies, calprotectin was measured in ascitic fluid, all of which reported higher calprotectin values in spontaneous bacterial peritonitis, while cut‐off points for its diagnosis were proposed in nine studies. Three studies reported higher faecal calprotectin levels in patients with hepatic encephalopathy and portal hypertension. Four studies evaluated faecal calprotectin and one plasma calprotectin as biomarkers for gut barrier integrity and bacterial translocation.ConclusionsCalprotectin is emerging as a promising biomarker in ACLD, particularly for the management of bacterial infections and alcohol‐related liver disease. Further research with better study designs should help to determine the feasibility of calprotectin measurement in routine clinical practice.
Role of alpha smooth muscle actin in odontogenic differentiation of dental pulp stem cells
Authors: Ma Zeyi , Shen Peiqi , Xu Xiaoqing , Li Weiyu , Li Yaoyin 
Published: October 2023

AbstractPulpotomy is an effective treatment for retaining vital pulp after pulp exposure caused by caries removal and/or trauma. The expression of alpha smooth muscle actin (α‐SMA) is increased during the wound‐healing process, and α‐SMA‐positive fibroblasts accelerate tissue repair. However, it remains largely unknown whether α‐SMA‐positive fibroblasts influence pulpal repair. In this study, we established an experimental rat pulpotomy model and found that the expression of α‐SMA was increased in dental pulp after pulpotomy relative to that in normal dental pulp. In vitro results showed that the expression of α‐SMA was increased during the induction of odontogenic differentiation in dental pulp stem cells (DPSCs) compared with untreated DPSCs. Moreover, α‐SMA overexpression promoted the odontogenic differentiation of DPSCs via increasing mitochondrial function. Mechanistically, α‐SMA overexpression activated the mammalian target of rapamycin (mTOR) signaling pathway. Inhibition of the mTOR signaling pathway by rapamycin decreased the mitochondrial function in α‐SMA‐overexpressing DPSCs and suppressed the odontogenic differentiation of DPSCs. Furthermore, we found that α‐SMA overexpression increased the secretion of transforming growth factor beta‐1 (TGF‐β1). In sum, our present study demonstrates a novel mechanism by which α‐SMA promotes odontogenic differentiation of DPSCs by increasing mitochondrial respiratory activity via the mTOR signaling pathway.
A systematic review of methodologies for studying behavioral imprinting
Authors: Chamberlain Mac L. , Kacelnik Alex , Bush Autumn , Hauber Mark E. 
Published: October 2023

AbstractBehavioral imprinting is a learning phenomenon by which animals acquire preferences for stimuli through perceptual exposure during critical periods, without substantial external reinforcement. Since being acknowledged in 1516 by Sir Thomas More in artificially incubated domestic chickens, imprinting has been reported in diverse species, across various sensory modalities, and during different life‐history stages. Due to this diversity, imprinting research uses highly varied methodologies, with distinctive differences between the methods employed for different types of imprinting. We systematically review relevant literature, identifying and describing the range of methodologies used to study imprinting across taxa and modalities. After compiling a representative dataset of 192 behavioral imprinting‐focused experiments, we categorize studies by imprinting sensory modality, focal species, ontogenetic stage addressed, and methods applied for both exposure and testing. The majority of studies in the sample focus on filial imprinting in precocial birds but nonfilial types, such as sexual or home range imprinting in altricial and non‐avian species, are also present, albeit at far lower proportions. Filial imprinting is studied across different sensory modalities, mostly through applying artificial stimuli, but nonfilial imprinting studies mainly use live animals as stimuli, without isolating the relevant sensory modalities. Most studies of filial imprinting measure preference by spatial proximity, following response, or the suppression of a fear response, whereas most studies of sexual imprinting employ the attempt frequency of sexual behaviors. Finally, we analyze the relative frequencies of methodological approaches in each imprinting category, to highlight potential biases due to uneven research effort rather than intrinsic biology. The patterns and biases in imprinting methodologies that we uncover hamper attempts to establish whether different forms of imprinting share mechanistic foundations, including whether imprinting constitutes a biologically meaningful learning category.
Poetic encounters in field work
Authors: Jensen Tommy , Mahmud Yashar 
Published: October 2023

AbstractIn this paper, we seek to belong to the “writing differently” turn in organization studies. We argue that writing poetry when doing field work is a way of disrupting and unsettling the objective scientific gaze, the scientific ideal of experiencing the world, and of opening for the Buberian world—the world as an encounter in itself. A tension framed by Buber as I‐It and I‐You. Rather than merely arguing that poetry can help us understand the world differently, we argue that poetry can help us encounter the world differently. Further, by telling two field work stories, we show that poetry can help the researcher to remain human in the field. Having hope in writing poetry when doing field work transcends the more politically and individually oriented engaged ethnography, realizing that field work as encounter—I and You—holds the possibility of not only companionship, trust, mercy, cooperation, forming of joint causes, dreams but also betrayal, plundering, exploitation, and force.
Success factors and barriers in interprofessional collaboration between dental hygienists and dietitians in community‐dwelling older people: Focus group interviews
Authors: Hollaar Vanessa R. Y. , Naumann Elke , Haverkort Elizabeth B. , Jerković‐Ćosić Katarina , Kok Wilhelmina E. , Schueren Marian A. E. de van der 
Published: October 2023

AbstractIntroductionPoor nutritional status can impair oral health while poor oral health can influence the individual's dietary intake, which may result in malnutrition. This interaction between nutritional status and oral health in older age requires attention, coordination and collaboration between healthcare professionals. This qualitative study explores dental hygienists' and dietitians' opinions about current collaboration with the aim of identifying success factors and barriers to this interprofessional collaboration.MethodsThree focus group interviews were held with Dutch dental hygienists and dietitians about nutritional and oral healthcare in community‐dwelling older people.ResultsIn total, 9 dietitians and 11 dental hygienists participated in three online focus group interviews. Dental hygienists and dietitians seldom collaborated or consulted with each other. They struggled with the professional boundaries of their field of expertise and experienced limited knowledge about the scope of practice of the other profession, resulting in conflicting information to patients about nutrition and oral health. Interprofessional education was scarce during their professional training. Organizational and network obstacles to collaborate were recognized, such as limitations in time, reimbursement and their professional network that often does not include a dietitian or dental hygienist.ConclusionDental hygienists and dietitians do not collaborate or consult each other about (mal)nutrition or oral health in community‐dwelling older people. To establish interprofessional collaboration, they need to gain knowledge and skills about nutrition and oral health to effectively recognize problems in nutritional status and oral health. Interprofessional education for healthcare professionals is needed to stimulate interprofessional collaboration to improve care for older people.
Notes towards a pedagogy of be‐longing: Rewilding art and design education
Authors: Poole Si 
Published: October 2023

AbstractThis article reflects on 4 years of research activities in the fields of horticulture and creative praxis. The initial project was a personal one and set out with a simple methodology of collecting, observing, and recording a specific genus of plants, that of Mentha. But as the specific question of whether a garden can, or should, be thought of as a work of art was raised it developed into an interactive, more‐than‐human dynamic between the researcher and multiple species. Ultimately, this led to a consideration of the positionality and interactions of the creative practitioner as critical, in order to develop a transdisciplinary praxis that explores the ecological and transformative potential of learning and healing through gardening. Through a reflexive narrative approach, the role of gardening in education, therefore, is positioned as an art and design praxis and as a partial remedy for several salient, contemporary global issues and challenges. A praxis that if not the complete remedy might at least help, in part, to remedy the damaging ecological experiences of adult and child learners alike, and as such, this article concludes with a provocation for teachers as artists and activists.
LncRNA SNHG15 regulates autophagy and prevents cerebral ischaemia‐reperfusion injury through mediating miR‐153‐3p/ATG5 axis
Authors: Yu Yunhu , Cai Yunpeng , Zhou Hang 
Published: October 2023

AbstractIschaemic stroke is a common cerebrovascular disease. Long non‐coding RNA (lncRNA) of small nucleolar RNA host gene (SNHG15) has been supposedly performed a regulatory role in many diseases. Nonetheless, the function of SNHG15 in cerebral ischaemia‐reperfusion injury has not been clarified. The OGD/R of Neuro2A cells simulated the ischaemic and reperfused states of the brain. Neuro2a cell line with stable transfection of plasmid with silent expression of SNHG15 was constructed. Neuro2a cell lines transfected with miR‐153‐3p mimic (miR‐153‐3p‐mimics) and miR‐153‐3p inhibitor (miR‐153‐3p‐inhibition) were constructed. Expression of SNHG15, mi R‐200a, FOXO3 and ATG7 in mouse brain tissue and N2a cells was identified by qRT‐PCR. Western blot (WB) analysis of mouse brain tissue and Neuro2a cells revealed the presence of the proteins ATG5, Cle‐caspase‐3, Bax, Bcl‐2, LC3 II/I and P62 (WB). The representation and distribution of LC3B were observed by immunofluorescence. The death of cells was measured using a technique called flow cytometry (FACS). SNHG15 was highly expressed in cerebral ischaemia‐reperfusion injury model. Down‐regulation of SNHG15 lead to lower apoptosis rate and decreased autophagy. Dual luciferase assay and co‐immunoprecipitation (CoIP) found lncRNA SNHG15/miR‐153‐3p/ATG5. Compared to cells transfected with NC suppression, cells transfected with miR‐153‐3p‐inhibition had substantially greater overexpression of LC 3 II/I, ATG5, cle‐Caspase‐3, and Bax, as determined by a recovery experiment, the apoptosis rate was elevated, yet both P62 and Bcl‐2 were significantly lower and LC3+ puncta per cells were significantly increased. Co‐transfection of miR‐153‐3p‐inhibition and sh‐SNHG15 could reverse these results. LncRNA SNHG15 regulated autophagy and prevented cerebral ischaemia‐reperfusion injury through mediating the miR‐153‐3p/ATG5 axis.
Parental psychopathology and posttraumatic stress in Puerto Ricans: the role of childhood adversity and parenting practices
Authors: Zhen‐Duan Jenny , Alvarez Kiara , Zhang Lulu , Cruz‐Gonzalez Mario , Kuo Josephine , Falgas‐Bagué Irene , Bird Hector , Canino Glorisa , Duarte Cristiane S. , Alegría Margarita 
Published: October 2023

BackgroundParental psychopathology is associated with their children's posttraumatic stress symptoms (PTSS). However, the mechanisms through which this occurs remain unclear. We hypothesized that exposure to childhood adversities is the mechanism linking parental psychopathology to child PTSS and that parenting practices moderated these associations.MethodsParticipants (N = 1,402) with an average age of 24.03 years old (SD = 2.20), were all Puerto Ricans (50% Male and 50% Female) from the Boricua Youth Study, which is a four‐wave longitudinal study spanning almost 20 years, following individuals from childhood (ages 5–13 at Wave 1) to young adulthood. Measured variables include parental psychopathology at Wave 1, childhood adversities and parenting practices at Waves 2–3, and PTSS at Wave 4. A traditional mediation model estimated the association between parental psychopathology and child PTSS via childhood adversities. A moderated mediation model was used to examine whether parenting practices moderated this mediation model.ResultsResults showed that the total effect of parental psychopathology at Wave 1 on PTSS at Wave 4 was fully mediated by childhood adversities at Waves 2–3 (direct effect b = 1.72, 95% CI = [−0.09, 3.83]; indirect effect b = 0.40, 95% CI = [0.15, 0.81]). In addition, the magnitude of this pathway varied by levels of parenting practices (i.e. parental monitoring and parent–child relationship quality). Specifically, the indirect effect of additional adversities in the psychopathology‐PTSS link was stronger with higher levels of parental monitoring but weaker with higher parent–child relationship quality scores.ConclusionsIntergenerational continuity of psychopathology may be mitigated through the prevention of additional childhood adversities via upstream interventions, emphasizing providing parents with mental health needs with parenting tools. Family‐based interventions focused on providing families with the tools to improve parent–child relationships may reduce the negative impact of childhood adversities on mental health across the life course.
Promoting resilience in ginger: Elicitor‐driven strategies to combat the rhizome rot disease
Authors: Archana T. S. , Mesta R. K. , Basavarajappa M. P. , Kiran Kumar K. C. 
Published: October 2023

AbstractGinger rhizome rot is one of the most important diseases brought about by the interaction of various pathogens. The present study revealed the association of Pythium aphanidermatum, Fusarium oxysporum, Fusarium solani, Sclerotium rolfsii, Ralstonia solanacearum and Meloidogyne hapla causing the rhizome rot of ginger. The use of specific primers revealed the species‐level identification of the pathogen and Koch postulates proved the pathogenicity of individual pathogen. Till date, there are no resistant varieties available and the available management strategies are cumbersome because of the complex nature of pathogens involved. In the present study, we evaluated the effect of different elicitors to induce resistance against complex pathogens. External application of elicitors resulted in higher expression of defence response genes such as the ethylene responsive transcription factor, HMGR, HMGS, HSP, ABC, MLO, WRKY, callose synthase, glucanase and PR‐5. All the genes were expressed in higher folds as compared to zero hours during the real‐time PCR analysis. External application of methyl jasmonate as prophylactic manner resulted in reduced per cent disease incidence and rhizome rot as compared to curative treatments.
Is snoozing losing? Why intermittent morning alarms are used and how they affect sleep, cognition, cortisol, and mood
Authors: Sundelin Tina , Landry Shane , Axelsson John 
Published: October 2023

SummaryPressing the snooze button is a common way to start the day, but little is known about this behaviour. Through two studies we determined predictors and effects of snoozing. In Study 1 (n = 1732) respondents described their waking habits, confirming that snoozing is widespread, especially in younger individuals and later chronotypes. Morning drowsiness and shorter sleep were also more common for those who snooze. Study 2 was a within‐subjects laboratory study (with polysomnography) on habitual snoozers (n = 31), showing that 30 min of snoozing improved or did not affect performance on cognitive tests directly upon rising compared to an abrupt awakening. Bayes factors indicate varying strengths of this evidence. Snoozing resulted in about 6 min of lost sleep, while preventing awakenings from slow‐wave sleep (N3). There were no clear effects of snoozing on the cortisol awakening response, morning sleepiness, mood, or overnight sleep architecture. A brief snooze period may thus help alleviate sleep inertia, without substantially disturbing sleep, for late chronotypes and those with morning drowsiness.
Connecting Reading Research on with Educational Practice and Policy
Authors: Supplee Lauren H. 
Published: October 2023

AbstractThere is a well‐known gap between research and practice. While there are investments in some strategies to address this gap, they are often not drawing from the existing research on how to improve research use. This article shares what we understand about the many ways research is used in education, why educators may use research, and under what conditions research is used in policy and practice. If scientists understand the levers that support research use, they may be able to create research that is more useful to decision‐makers and share that research through effective strategies such as using boundary spanners, individuals who straddle both the research and practice worlds. The article concludes by sharing some examples of promising strategies to improve the use of research in education such as research–practice partnerships.
Executive Function, Academic Skills, and Learning Disabilities: Integrative Commentary
Authors: Landi Nicole 
Published: October 2023

ABSTRACTThis special issue of Mind, Brain, and Education includes articles on the role of executive functions (EFs) in academic skills and learning disabilities, a commentary on the construct of EF and the neurobiology of reading, and a commentary on connecting research to practice. These products are the result of a weeklong TDF (The Dyslexia Foundation) conference in Bermuda, during the summer of 2022. Each paper in the second half of this issue considers EFs from a different perspective or relates them to a different academic skill or outcome (e.g., reading, math, response to intervention). In this commentary, I discuss how consideration of EFs improves our understanding of individual differences in academic skills and learning disabilities, such as reading disability (RD) and math disability (MD). I also discuss the implications of the reported findings and ideas for improving future research, practice, and policy.
Aquinas on The Distinction Between Esse and Esse: How the Name ‘Esse’ Can Signify Essence
Authors: Doolan Gregory T. 
Published: October 2023

AbstractIn a number of texts throughout his career, Thomas Aquinas identifies different senses of the term ‘esse’. Most notably, he notes that according to one sense, the term signifies the act of existence (actus essendi), which he famously holds is really distinct from essence in all beings other than God. Perhaps surprisingly, he also notes on a number of occasions that according to another sense, the term ‘esse’ can signify that very principle that he says is distinct from the act of existence, namely, essence. In light of Aquinas's semantic theory, this paper investigates how he coherently holds within his metaphysical system that this term ‘esse’ can signify in different ways both essence and the act of existence. More broadly, what it shows is how, for Aquinas, the metaphysician can look to the modes of signification (modi significandi) of terms and as well as their modes of predication (modi praedicandi) to draw careful conclusions about the modes of existence (modi essendi) of real beings. These considerations reveal that in Aquinas's view, although the grammarian and logician in their way are also concerned with these semantic modes, it is not their job to employ them to discern the various senses of the term ‘being’ or the fundamental modes of being. In the end, this is a task for the metaphysician.