bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical significance of micronutrient status and vaginal microbiocenosis in pregnant women and correction of indentified disorders
Authors: Kukharchyk Yu. V. , Gutikova L. V. 
Published: December 2023

Objective: to conduct a clinical analysis and evaluate the significance of micronutrient status and vaginal microbiocenosis in pregnant women and develop a method for correcting the identified disorders based on the use of Bellakt Mama+ powdered milk product. Materials and methods. We conducted a prospective study on the basis of the professorial advisory center of the EE “Grodno State Medical University”. In the course of the work, we examined 110 pregnant women, 55 of whom took Bellakt MAMA + dry milk product for 3 months, and the second half were observed only according to the clinical protocol. The assessment was made: anamnestic - assessment of the anamnesis of life and disease; generally accepted clinical, laboratory and instrumental (ultrasound examination of the pelvic organs) research methods. Performed blood sampling from the cubital vein in the morning on an empty stomach with the determination of the levels of ferritin, calcium i, iron, total vitamin D, folic acid, osteocalcin. An assessment of the biocoenosis of the urogenital tract was carried out “Femoflor Screen”; statistical processing of the results was carried out. Results. We found that in patients who took a dry dairy product of Belarusian production, a persistent positive trend in the increase in the level of folic acid (p = 0,0049), total vitamin D (p = 0,0041), serum iron (p = 0,0041) was established, ferritin (p = 0,0040), as well as improvement of the vaginal biocoenosis (p = 0,0040). There were no statistically significant differences in the levels of ionized calcium and osteocalcin. It should be noted that the patients of the main group had no complaints of discomfort in large joints, bones and cramps in the calf muscles, in contrast to the women of the control group. Conclusion. The above results confirm the need to control and correct micronutrient deficiency and vaginal dysbiosis in women at the stage of preconception preparation and in the first trimester of pregnancy.
Analysis of the outcomes of myocardial infarction against the background of chronic obstructive pulmonary disease among residents of the Astrakhan region
Authors: Prokof'eva T. V. , Polunina O. S. , Polunina E. A. , Sevost’yanova I. V. 
Published: December 2023

Objective. To analyse the course of coronary heart disease within a year after the development of myocardial infarction in residents of Astrakhan region with chronic obstructive pulmonary disease. Materials and Methods. We examined 325 patients with myocardial infarction, residents of Astrakhan region. 195 patients had heart attacks against the background of COPD and 130 patients without COPD. During 12-month follow-up 30 people dropped out - 19 in the group of patients with myocardial infarction against COPD, 11 in the group of patients with myocardial infarction without COPD. Correspondingly, by the end of the observation period the number of patients under observation was: 176 - in the group of patients with myocardial infarction against COPD, and 119 - in the group of patients with myocardial infarction without COPD. Results. It was found that in patients with myocardial infarction against COPD the annual mortality from conditions associated with cardiovascular pathology was twice as frequent as in patients with MI without COPD. There was also a tendency to more frequent development of recurrent myocardial infarction. In the structure of mortality in patients with myocardial infarction against COPD and without COPD and there was a tendency to a more frequent occurrence of acute heart failure expressed stages (Killip III-IV) and decompensation of chronic heart failure as causes of mortality. The odds of developing a combined endpoint, including recurrent myocardial infarction, stroke and mortality from cardiac causes, among patients with myocardial infarction against COPD were 2.7 times higher compared to patients with myocardial infarction without COPD. The combined endpoint, which combines clinically significant events in patients with myocardial infarction, makes the existing differences in the outcomes of infarction in patients with and without COPD evident.
Economic Justification of the Development of the Master Plan for Suburbanized Territories on the Example of Irkutsk Agglomeration
Authors: Astafiev Sergey 
Published: December 2023

Accodring to regional strategy for socio-economic development all municipalities are required to develop or adapt to the regional development strategy of their municipality, which makes this study particlualry relevant. Since the Khomutovo municipality, which is part of the urban agglomeration of the cities of Irkutsk, Angarsk and Shelekhov, has not yet developed a strategy, and the regional government approved the strategy of the Irkutsk region until 2036 only at the end of 2021, the purpose of the study was to develop a strategy for the socio-economic development of this municipality. The research methods were economic and mathematical methods of forecasting, methods of graphical analysis of the boundaries of built-up areas over the past 30 years and forecasting based on the revealed dynamics of the development of the territory of the municipality until 2050. The study showed that the growth rate of development in the territory of the Khomutovo municipality is linear, that is, from year to year the territory of the municipality increases by approximately the same amount, but the population is in dire need of missing social infrastructure, high-quality roads, sidewalks, recreation areas etc. As a result of the study we supported a strategy to increase the number of jobs in the rural area by moving international airport from Irkutsk to the territory of the Khomutovo municipality.
Direccionamiento Estratégico: estudio de caso múltiple en pequeñas y medianas empresas en la ciudad de Medellín
Authors: Bedoya-Jiménez Mauricio Alejandro , Quintero-Arango Luis Fernando 
Published: December 2023

El presente manuscrito tiene por objetivo describir la morfología organizacional y la planeación estratégica de Mipymes en la ciudad de Medellín, vinculando la articulación entre la planeación estratégica (PE) y la morfología organizacional (MO). Se utiliza el enfoque cualitativo con un diseño descriptivo, bajo un método fenomenológico, utilizando como instrumento de recolección de información la entrevista semi estructurada y para los resultados el análisis categorial. Se seleccionan siete empresas, de diferentes sectores económicos, que fueran Mipymes con el criterio de conveniencia, cercanía y fácil acceso a la información. Los resultados generales demuestran que se encuentran fallas en la PE al no responder a los requerimientos del mercado, su MO por tanto no se encuentra alineada con dichas necesidades; con respecto a la cultura organizacional no se logra encontrar que exista al interior de las empresas analizadas una clara concepción de su importancia, ya que se presentaba deficiencias en el trabajo en equipo y en retención de personal. Desde el análisis de los resultados se brinda una orientación a las Mipymes, para que puedan considerar que la PE brinda rumbo a la organización y puede permitir tomar decisiones de mejora continua; así mismo, la MO puede dar una identidad corporativa que identifique a una empresa logrando consolidar estrategias endógenas que busquen la permanencia de la organización en el mercado.
Insights of hematological parameters in dengue virus-infected patients
Authors: Thapa Tika Bahadur , Bhattarai Bibek Raj , Maharjan Sujina , Pokhrel Sushant , Sapkota Manisha 
Published: December 2023

: Early and accurate diagnosis of dengue is critical for prompt treatment and avoiding severe complications. Thus, the present study aimed to evaluate the serological and hematological parameters for predicting the dengue virus infection. : A laboratory-based cross-sectional study was conducted among the patients who visited Sumeru Hospital, Lalitpur, Nepal, from July 2022 to June 2023. Blood samples were collected from suspected dengue cases and tested using the rapid diagnostic immunochromatography (ICT) method, and hematological parameters were also assessed. The Mann-Whitney U test compared continuous variables between dengue-infected and non-infected groups. A binary logistic regression analysis was done to evaluate the association of variables for dengue positivity.: When compared to dengue-negative cases, dengue-positive cases had thrombocytopenia, leucopenia, erythrocytosis, high hemoconcentration, low mean corpuscular hemoglobin (MCH), and mean corpuscular hemoglobin concentration (MCHC). However, binary logistic regression predicted platelet count, total leucocyte count, MCH, MCHC, neutrophil count and lymphocyte count as significant predictors of dengue positivity.: This study revealed the characteristics and demographics of dengue-positive cases and their associations with hematological parameters. Furthermore, the identified predictive markers can help healthcare professionals diagnose and manage dengue cases more promptly, potentially reducing the disease's burden.
Editorial
Authors: Korver Wim , Eijkelenbergh Pascal 
Published: December 2023

Given the current status of research and implementation, the various contributions show that research, and in particular the analysis of the impacts of reforms, must proceed in parallel with implementation, in order to create a virtuous cycle in which research and policy making mutually feed each other. Besides a “window of opportunity” is open for what concerns interurban and urban transport. Several experiences in different European cities confirm that an increasing number of cities are already well into the process of rationalising and increasing the sustainability of their transport systems, notably through the design and implementation of pricing policies. And also for inter-urban transport things are moving, e.g. the proposed revised Eurovignette Directive can be seen as a step in the right direction, although still containing many constraints which would prevent fair and efficient pricing of road freight vehicles. In general it can be said that Social Marginal Cost Pricing is still developing. Most practical experiences only use simple pricing schemes, which are far from optimal prices. In the long term fine-tuning of objectives and schemes will be necessary. Some general recommendations based on several Imprint seminars and the papers presented in this issue.
Effect of Peganum harmala seeds extract on the hepatic tissue structure and fetus of mice
Authors: Samira Musa Sasi  , Al ghoul Nagia , Awayn Nuri , El ghoul Ahmed , Prastiya Ragil 
Published: December 2023

Peganum harmala is one of the most used plants for the treatment of many diseases. Its effective compounds have pharmaceutical and medicinal properties. This study aims to determine the effect of aqueous extract of harmala plant seeds on body and liver weight, aspartate aminotransferase (AST), alanine transaminase (ALT), and the histological structure of liver of mice, as well as the size of the fetuses sired by treated mice. Sixteen adult male mice were divided into two groups of eight. The first group (control) was given distilled water orally, while the second group received the aqueous extract of harmala seeds at a dose of 300 mg/kg bw for three weeks. three untreated females were housed with one treated male for mating. At the end of the treatment, six male mice of each group were weighed and killed. Liver was extracted, weighed and its enzymes were measured. Also, sections of the liver were prepared for histological examination. The results showed a decrease in the body weight of the treated mice and a significant increase in the average weight of the fetuses compared with the control group, as well as marked changes in the hepatic tissue structure. There was no impact of the extract on fetal body length, liver weight and hepatic enzymes (AST and ALT) of treated mice. Further studies should be conducted to determine a safe dose that does not affect any organ in the body, so that it can be used for the treatment of many diseases.
Do abnormal accruals influence abnormal tone in the CEO statements of the top 40 JSE-listed companies?
Authors: Mlawu Lonwabo , Matenda Frank Ranganai , Sibanda Mabutho 
Published: December 2023

The aim of this study is to examine the effect of abnormal accruals on abnormal tone in the Chief Executive Officer (CEO) statements of South Africa’s (SA) top 40 Johannesburg Stock Exchange (JSE) listed businesses in the 2021 financial year. This study employs the quantile regression analysis and the generalised linear regression model. For this evaluation, the Top 40 JSE-listed firms' integrated annual reports (IARs), which include the annual financial statements and CEO statements, were extracted from the companies' official web pages. Findings revealed that abnormal accruals have a negative relationship with the abnormal tone used in the CEO statements of the top 40 JSE-listed companies. i.e., anomalous accruals and irregular tone move in different directions, as abnormal accruals increase, the abnormal tone in CEO statements decreases. This suggests that abnormal accruals and abnormal tone do not co-occur and that companies with abnormal accruals do not conceal them using abnormal tone in their CEO statements. We recommend that the amount of flexibility and judgment given to preparers of annual financial statements be reduced to lessen the use of earnings management practices. The research adds to the sparse literature on tone management and earnings management in developing nations, particularly SA.
ISENÇÃO SOBRE A DISTRIBUIÇÃO DE DIVIDENDOS E O APARTHEID FISCAL BRASILEIRO
Authors: Bomfim Gilson Pacheco 
Published: December 2023

Resumo: O presente artigo objetiva analisar a compatibilidade da isenção de IRPF sobre a distribuição de dividendos com a Constituição de 1988, bem como se o citado benefício fiscal tem contribuído ou se relaciona com um regime de segregação fiscal entre contribuintes. Para tanto, a investigação busca identificar a estrutura normativa da tributação sobre a renda no Brasil, os resultados que a aludida desoneração tem produzido e sua compatibilidade com os fundamentos, princípios e finalidades eleitas pelo Texto Constitucional. Constatou-se que 1) a desoneração total sobre dividendos produz resultados absurdamente regressivos, que colidem frontalmente com a isonomia, progressividade, generalidade e universalidade na tributação sobre a renda, além de outros princípios e valores constitucionais; 2) o mencionado incentivo fiscal colabora para a construção de um apartheid fiscal, onde a imensa maioria dos contribuintes se submete à tributação sobre seus vencimentos, enquanto outros ( a minoria) se valem do privilégio fiscal para não pagar o imposto; 3) essa situação contribui para aumentar a concentração de renda e riqueza entre os contribuintes mais abastados. A pesquisa utiliza dados disponibilizados pela Receita Federal e a revisão da literatura especializada como instrumental, servindo-se de metodologia indutiva e explicativa, com abordagem quantitativa e qualitativa dos dados investigados.
Dementia and Hip Fractures
Authors: Zabawa Luke , Choubey Apurva S. , Drake Brett , Mayo Joel , Mejia Alfonso 
Published: December 2023

» The elderly population is the fastest growing demographic, and the number of dementia cases in the United States is expected to double to 10 million by 2050.» Patients with dementia are at 3× higher risk of hip fractures and have higher morbidity and mortality after hip fractures.» Hip fracture patients with dementia benefit from early analgesia and timely surgical fixation of fracture.» Early and intensive inpatient rehabilitation is associated with improved postoperative outcomes in patients with dementia.» Coordination of care within a “orthogeriatric” team decreases mortality, and fracture liaison services show potential for improving long-term outcomes in hip fracture patients with dementia.
Geochemical Characteristics and Geological Significance of Mud Shale of the Second Member, Permian Lucaogou Formation, Jimsar Sag, Junggar Basin, NW China
Authors: Jin J. , Liu J. , Lou Z. , Wang J. , Li J. , Zhu R. , Wang Y. 
Published: December 2023

Abstract
––The Lucaogou Formation in Jimsar sag is an important shale oil-producing layer in the Junggar basin. In this paper, core data, organic carbon, rock pyrolysis, biomarker compounds, and organic matter group component separation were used to study the sedimentary environment, parent material type, organic maturity and oil-bearing property of mud shale of the Second member of the Lucaogou Formation. The results showed that the sedimentary environment is a semi-oxidation and semi-reduction environment. The parent material is mainly aquatic with minor input of higher plants. The average TOC is 7.43%, the average value of hydrocarbon generation potential (S1+S2) is 50.54 mg/g, and the average value of Tmax is 446 °C, showing high maturity of the mud shale. The chloroform bitumen “A” features high saturated hydrocarbon content (34.10% on average), low aromatic hydrocarbon content (15.39% on average), and high saturated/aromatic ratio (2.54). The carbon number of saturated hydrocarbons is distributed between n-C13 and n-C33. Their peak are mainly n-C17 and n-C23, which are biased toward medium-low molecular weight alkanes. The average of the ΣC21–/ΣC22+ is 1.19, indicating that the alkane has advantage of short chain. The mud shale in the Second member of the Lucaogou Formation has a large sedimentary thickness, high organic matter content, and high oil generation potential. It is an important replacement target for shale oil in Jimsar sag and has important exploration significance in the future.
CV classification in a big data environment using BERT and alignment learning
Authors: CHAFI Soumia , KABIL Mustapha , KAMOUSS Abdessamad 
Published: December 2023

Abstract
Today, text classification has always been a crucial discipline in the field of text data processing. However, with the advent of Big Data, text classification has reached new heights in terms of the volume of data to be processed and the complexity of the tasks. This task is of great importance in many fields, such as spam detection, sentiment analysis, document categorization, content recommendation and many more. In this work, we focus specifically on resume classification, an area that presents unique challenges due to diverse formats, ambiguous language, and variations in applicants' work experiences. We propose an innovative approach for distributed classification of CVs using contextual alignment techniques with the job offer and the pre-trained language model BERT (Bidirectional Encoder Representations from Transformers) which constitutes a major advance in this field , and using RNN (Recurrent Neural Network) to solve text classification problems. We use a distributed processing approach to leverage the parallel computing power of Spark, enabling large volumes of data to be processed efficiently. The main objective of our study is to improve the relevance of CV classification by leveraging the pre-trained language models and distributed processing power of Spark.
Behavioral Intentions towards Climate-Smart Practices and Rural Farmer’s Food-Nutrition Security: A Micro Economic-Level Evidence
Authors: Omotoso Abeeb Babatunde , Omotayo Abiodun Olusola 
Published: December 2023

Abstract
The behavioural intention (BI) of adopting climate-smart agricultural (CSA) practices plays a vital role in effectively mitigating the adverse impacts of climate shocks experienced by smallholder farmers in South Africa (SA). Nevertheless, there is a scarcity of information about the socio-psychological factors that influence farmers' adoption of CSA practices and their impacts on food-nutrition security (FNS). The study examined the BI of adopting CSA and its impact on the FNS of farming households in SA. A multistage sampling procedure was employed in selecting rural maize farmers across some selected villages in South Africa. To understand the association between behavioural adoption of CSA and FNS of farming households, an endogenous switching regression model was employed while household dietary diversity score (HDDS) and household food security score (HFIAS) were used to determine the FNS status of the households. The findings indicate that the behavioural intentions of farmers had a significant influence on their desire to implement CSA practices, hence FNS status. Therefore, the findings emphasized the significance of socio-psychological variables (behavioural intentions) in elucidating the adoption decision of CSA practices and its impact on FNS in SA. Following this backdrop, a concerted effort to raise knowledge of CSA practices through the dissemination of pertinent information will exert influence on the farmers' adoption behaviour towards CSA practices which is capable of improving the FNS of the rural maize farmers.
Whole Mitogenome Sequencing Uncovers a Relation Between Mitochondrial Heteroplasmy and Leprosy Severity
Authors: Souza Felipe Gouvea , Silva Moisés Batista , Araújo Gilderlanio S. , Silva Caio S. , Pinheiro Andrey Henrique Gama , Cáceres-Durán Miguel Ángel , Santana-da-Silva Mayara Natália , Pinto Pablo , Gobbo Angélica Rita , Costa Patrícia Fagundes , Salgado Claudio Guedes , Ribeiro-dos-Santos Ândrea , Cavalcante Giovanna C. 
Published: December 2023

Abstract
Background
In recent years, a mitochondria/immune system interaction has been proposed, so that variants of mitochondrial genome and levels of heteroplasmy might deregulate important metabolic processes in fighting infections, such as leprosy. We sequenced the whole mitochondrial genome to investigate variants and heteroplasmy levels, considering patients with different clinical forms of leprosy and household contacts.
Results
We found 116 variants in at least two of the subtypes of the case group (Borderline Tuberculoid, Borderline Lepromatous, Lepromatous), suggesting a possible clinical significance to these variants. Notably, 15 variants were exclusively found in these three clinical forms, of which five variants stands out for being missense (m.3791T > C in MT-ND1, m.5317C > A in MT-ND2, m.8545G > A in MT-ATP8, m.9044T > C in MT-ATP6 and m.15837T > C in MT-CYB). In addition, we found 26 variants shared only by leprosy poles, of which two are characterized as missense (m.4248T > C in MT-ND1 and m.8027G > A in MT-CO2).
Conclusion
We found a significant number of variants and heteroplasmy levels in the leprosy patients from our cohort, suggesting for the first time that the mitogenome might be involved with the leprosy process, distinction of clinical forms and severity. Thus, future studies are needed to help understand the genetic consequences of this variants.