bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation and assessment of risk of pesticide residue in vegetables, soil and water samples of few district of Northern India
Authors: mishra sudeep , singh Mukesh Kumar , Saini Mahesh Kumar , Alam Samsul , Thakur Lalitesh Kumar 
Published: February 2024

Abstract
The main motive of the study was to determine pesticides residues in 16 different vegetables grown in four districts i.e Rohtak, Karnal, Hisar, Panipat of Haryana, India. In total 102 vegetables of field and market for the pesticide residue analysis during the year 2019-2020. Also along with that 46 soil and 50 water samples were a collected from the same four districts. 161 pesticideswere screened for their presence of pesticide residue. Analysis of samples were done using liquid chromatography–tandem mass spectrometry (LC-MS/MS) (90 pesticides) and gas chromatography–tandem mass spectrometry (GC-MS/MS) (71). The extraction of a multi-residue method using QuEChERS method for vegetables and traditional partitioning and shaking method for water and soil respectively. The evaluation of detected residues where compared with the maximum residue limit (MRL) of FSSAI and European regulations. A total of 31 samples (30.39%) of vegetables, 44 samples (95.65%) of soil and 34 samples (68.0%) of water were detected with pesticide residue. Alpha cypermethrin, hexaconazole and carbendizim were detected in low concentration below MRL and chlorpyrifos, cypermethrin, pendimethalin, buprofezin, butachlor and deltamethrin were deteted in higher concentration in some samples. Chlorpyrifos, cypermethrin, pendimethlin and butachlor were commonly detected. As the result of the study, it is necessary that the government need to support the the monitoring of pesticide residues in vegetables and other environmental samples for consumers’ health.
Enhanced protocatechuic acid production using metabolically engineered Corynebacterium glutamicum
Authors: Chung Jiwoon , Cho Jaehoon , Shin Woo-Shik , Park Chulhwan 
Published: February 2024

Abstract
Protocatechuate acid (PCA) is a phenolic acid naturally synthesized by various microorganisms. To enhance PCA production during fermentation using Corynebacterium glutamicum, a statistical optimization of the production medium was performed using full factorial design, the steepest ascent method, and the response surface method. The optimized production medium enabled PCA production of over 5 g/L in a 72-h batch culture. PCA cytotoxicity affected strain growth and PCA production rate, with an inhibitory concentration of approximately 5 g/L in the fermentation broth. Finally, continuous fermentation was operated for 150 h in steady-state mode, maintaining the concentration of PCA below 5 g/L. The optimization method established in this study successfully increased PCA production levels, and the findings presented herein are anticipated to contribute to the industrialization of PCA production using C. glutamicum.
Impact of Climate Change and Land Use Land Cover Change on Stream Flow of the Teesta River Basin under CMIP6 Climate Scenarios
Authors: Rahman Syadur , Islam AKM Saiful 
Published: February 2024

Abstract
The Teesta basin, shared by Bangladesh and India, undergoes profound changes due to land use and land cover (LULC) dynamics combined with climate change, significantly impacting its water balance. This study intends to analyse the combined effects of future LULC changes and climate change on the stream flow of the Teesta River. Employing a cellular-automata model, we accurately predicted LULC for 2020 and projected scenarios for 2050 and 2080. A semi-distributed hydrological model, Soil Water Assessment Tool (SWAT) is used to generate flow for the base period (1995-2014), the near future (2035-2064), and the far future (2071-2100). SWAT model is forced by 8 General Circulation Models (GCMs) under two Socioeconomic Pathways (SSP245 and SSP585). Satellite image analysis showed notable LULC changes, with substantial increases in agricultural (0.49%), water bodies (4.24%) and settlement areas (1.67%), while a decrease in forest (1.45%) and sand bar (5.49%) decreased from 2000 to 2010. During 2010 and 2020, increases in agricultural (2.77%), water bodies (7.7%) and settlement areas (8.59%), while decreases in forest (1.36%) and sand bar (0.18%) were found. The CA-Markov prediction indicates significant future increases in settlements and agricultural land by 2050 and 2080, coupled with reductions in forest, water, and snow cover. The calibrated and validated SWAT model effectively simulated discharge, yielding satisfactory results. Projected changes in discharge during the monsoon and winter periods were examined under different scenarios. Monsoon discharge is predicted to increase by 26% to 38% in the near future and 30% to 45% in the far future. Conversely, the winter/dry period may experience a decrease of 46% to 49% in the near future and 38% in the far future for SSP245 and SSP585 scenarios, respectively. Considering LULC changes to account, additional discharge increases during the monsoon are projected, with slight increases in the dry period during the near future and decreases during the far future. This study anticipates an increasing trend in peak flow during the monsoon and a declining trend in mean flow during winter without further upstream water control. Understanding and managing the combined effects of LULC changes and climate change on the hydrological dynamics of the basin is of utmost importance for sustainable water resource management in the region.
Fabrication of Low Cost Thermoresponsive Microgel@CuO Catalyst for Rapid Reduction of Methylene Blue Dye
Authors: Prasad Tarkeshwar , Pande Poorn Prakash , Kumar Krishna , Rai Shailza , Chaudhary Aradhna , Das Anupam , Tiwari Rudra Mani , Tungala Kranthikumar , Singh Vinai Kumar 
Published: February 2024

Abstract

The present study details the catalytic reduction of water pollutants (Methylene blue). In this research, the synthesis of microgels was achieved through free-radical emulsion polymerization techniques employing HEMA monomer as a crosslinker. Three different grades of microgel have synthesized by varying the amount of N-vinyl caprolactam. Copper-oxide nanoparticles were successfully incorporated into polymeric microgels through hydrothermal methods for catalytic reduction applications. Characterization of both microgels and microgel-nanoparticle composites was conducted using various techniques like as: Fourier transform infrared spectroscopy (FT-IR), powder X-Ray diffraction (Powder XRD) Dynamic light scattering (DLS), Thermogravimetric analysis (TGA), Scanning electron microscopy (SEM) and Transmission electron microscopy (TEM). The catalytic reduction of methylene blue (MB) was characterized using ultraviolet-visible spectrometry. The catalytic reduction efficiency of the dye was measured by optimizing the parameter effect of crosslinking, temperature responsive monomer feed, temperature and amount of reducing agent (NaBH4). Microgel nanocomposites respond to efficient catalysis at higher NVCL feed with moderate dose of NABH4.
Welfare evaluation of fat-rumped lambs under stall feeding condition with different feeder design
Authors: Mohapatra Arpita , Kerketta Shilpi , Kumar Vijay , De Kalyan , Dangi Satyaveer Singh , Singh Raghvendar 
Published: February 2024

Abstract
Animal welfare is directly related to animal performance and farm profit. It is associated with their autonomy to take feed and water along with lack of discomfort. Feeding welfare determines farm profit as major cost of a farm is associated with feed. The objective of the study was to investigate the effect of feeder design on lamb welfare evaluated through feeding behavior and lamb performance. Sixteen growing fat-rumped lambs of 3–4 months were categorized into 2 groups with an average weight of 23.20 ± 0.25kg. Group I lambs were fed in conventional feeder i.e. without divider and group II in designed feeder i.e. with divider respectively. The eating time was significantly (P < 0.05) low in group I with longer and strong agonistic behavior suggesting intense competition within the group. This group showed minimal weight gain and maximal feed wastage due to extreme struggle for food during the period of the study. The time spent in comfort behaviors like lying rumination was more and agonistic behavior was less in group II lambs. They showed significantly (P < 0.05) higher body weight gain. This can be concluded from the study that group feeding of growing lambs in feeder with divider allocates designated space for individual lamb, reduce agonistic behavior and bring better growth in lambs under stall feeding conditions.
Vesical stone formation caused by a forgotten and migrated intrauterine contraceptive: A case report with literature review
Authors: Hameed Farooq , Anwaar Adeel , Anwar Mamoona , Anwar Maria 
Published: February 2024

Abstract
Background
As widely known, an intrauterine device (IUD) is a small, typically T-shaped contraceptive device that offers long-term reversible birth control. However, neglecting to remove the IUD can lead to severe complications. This case report showcases an exceptional instance that underscores the potential risks associated with retention of an IUD.
Case Presentation
This case report documents a 40-year-old female who failed to remove her intrauterine device for eight years. Upon her visit to our clinic, she presented with increased urinary frequency, burning micturition, dysuria, and discomfort while emptying her bladder. Medical review consisting of ultrasound (KUB) and X-ray pelvis revealed the intrauterine device had migrated and was encrusted with a stone. We used Holmium laser lithotripsy to break down the stone, before using cystoscope to manually remove the intrauterine device. She made a rapid recovery without any complications.
Conclusions
In order to raise awareness about forgotten or misplaced IUDs and their complications, we are presenting a case of complete intravesical IUD migration at our clinic. This serves as an educational opportunity to shed light on this uncommon occurrence and emphasize the importance of timely removal and follow-up in patients using intrauterine devices (IUDs).
Immunogenicity and efficacy of XBB.1.5 rS vaccine against EG.5.1 variant of SARS-CoV-2 in Syrian hamsters
Authors: Boon Jacco , Soudani Nadia , Bricker Traci , Darling Tamarand , Seehra Kuljeet , Patel Nita , Guebre-Xabier Mimi , Smith Gale , Suthar Mehul , Ellebedy Ali , Davis-Gardner Meredith 
Published: February 2024

Abstract
The continued emergence of SARS-CoV-2 variants necessitates updating COVID-19 vaccines to match circulating strains. The immunogenicity and efficacy of these vaccines must be tested in pre-clinical animal models. In Syrian hamsters, we measured the humoral and cellular immune response after immunization with the nanoparticle recombinant Spike (S) protein-based COVID-19 vaccine (Novavax, Inc.). We also compared the efficacy of the updated monovalent XBB.1.5 variant vaccine to previous COVID-19 vaccines for the induction of XBB.1.5 and EG.5.1 neutralizing antibodies and protection against a challenge with the EG.5.1 variant of SARS-CoV-2. Immunization induced high levels of spike-specific serum IgG and IgA antibodies, S-specific IgG and IgA antibody secreting cells, and antigen specific CD4 + T-cells. The XBB.1.5 and XBB.1.16 vaccines, but not the Prototype vaccine, induced high levels of neutralizing antibodies against XBB.1.5 and EG.5.1 variants of SARS-CoV-2. Upon challenge with the Omicron EG.5.1 variant, the XBB.1.5 and XBB.1.16 vaccines reduced the virus load in the lungs, nasal turbinates, trachea and nasal washes. The bivalent vaccine continued to offer protection in the trachea and lungs, but protection was reduced in the upper airways. In contrast, the monovalent Prototype vaccine no longer offered good protection, and breakthrough infections were observed in all animals and tissues. Thus, the protein-based XBB.1.5 vaccine is immunogenic and can protect against the Omicron EG.5.1 variant in the Syrian hamster model.
Distinct sources of resting-state EEG microstates in amyotrophic lateral sclerosis
Authors: Metzger Marjorie , Dukic Stefan , McMackin Roisin , Giglia Eileen , Mitchell Matthew , Bista Saroj , Tadjine Yasmine , Sirenko Vladyslav , Plaitano Serena , Coffey Amina , McManus Lara , Sharp Adelais Farnell , Mehra Prabhav , Heverin Mark , Bede Peter , Muthuraman Muthuraman , Pender Niall , Hardiman Orla , Nasseroleslami Bahman 
Published: February 2024

Abstract
Brain microstates are a well-established method for the dynamic analysis of resting-state electroencephalogram (EEG). We observed four quasi-stable, transient and reoccurring resting-state topographies in the high density EEG data (128 electrodes, 3x2 min recording blocks). The four microstates were reliably observed across conditions: individuals with Amyotrophic lateral sclerosis (ALS) (n = 99) versus age-matched healthy controls (HC, n = 78).
To improve the understanding of the neural mechanisms underlying microstates, we estimated the sources of microstates topographies. A general linear model was applied to predict the microstate sequence based on EEG-estimated source space time courses. High reproducibility across participants of influential brain sources led to the identification of four microstate specific networks. Some brain regions contributed to several microstate networks, which may indicate that these regions (including the precuneus, the superior frontal gyrus and the hippocampus) are functional neuronal ‘hubs’ of connection. Additionally, distinct source patterns were observed between ALS patients and healthy controls, highlighting potential functional changes in the brain networks in ALS.
Coupled CFD-FEM Analysis of the Damage Causes of the Retention Bunker: A Case Study at Hard Coal Mine
Authors: Janoszek Tomasz , Rotkegel Marek 
Published: February 2024

Abstract

Underground coal storage bunkers are built to equalize coal output, guarantee continuity of the excavated coal transport, and store coal at the point where the nature of the transport changes from continuous to periodic. The physical properties of stored coal in underground coal storage bunkers are unpredictable and prone to sudden changes, especially for the coal mines that operate under water hazards. Interaction with underground water changes the state of solid coal and forms a coal-water mixture. The hydromixture radically changes the conditions of internal hydrostatic loading. The main goal of the paper was to determine the values of pressure field variations exerted by the flowing hydromixture. The influence of the internal pressure loading change on the stress distribution in the underground coal storage bunker was tested. The changes in the underground coal storage bunker's pressure caused by the flow of hydromixture were examined using the computational fluid dynamics (CFD) method. The damage to an underground coal storage bunker due to stress distribution was examined using the finite element method (FEM). The results of the CFD numerical simulation were compared with the mathematical models.
Semi-empirical modeling of weaving process for high-quality and property parts in plasma arc directed energy deposition
Authors: Suhr Jonghwan , Kim Min-Kyeom , Fang Yongjian , Kim Juwon , Heo Sungho , Jang Youngseob , Ahn Heesung , Kim Yonghwi , Lee Wanki 
Published: February 2024

Abstract
Plasma arc directed energy deposition (DED) technology faces challenges, such as low resolution, nonuniform layers, defects, and severe deformation, despite its advantage of rapid, large-scale manufacturing. Although a weaving process offers potential solutions to these issues, its optimization is challenging due to more processing parameters over a stringer process. To address this, we introduce a semi-empirical modeling approach for the weaving process using 316L austenitic stainless steel. This modeling enables the empirical determination of printable region and the numerical alleviation of residual stress and deformation, using multi-heat sources to significantly reduce computing time. Our findings show that a larger weaving process notably decreases bead aspect ratio, dilution, and thermal deformation, thereby reducing uneven beads and layers, compared to the stringer process. Additionally, it enhances heat dissipation and minimizes the heat-affected zone, leading to a remarkable 69.98% increase in elongation while maintaining tensile strength at 486 MPa. This innovative approach offers a practical solution for enhancing the weaving process, overcoming its prevalent challenges to produce high-quality parts with improved properties.
Translation and psychometric evaluation of Persian version of the oral presentation evaluation scale in nursing students
Authors: Rahmatkhah Tahmine , Dashti-Kalantar Rajab , Vosoghi Nazila , Mirzaei Alireza , Mehri Saeid 
Published: February 2024

Abstract
Background
Delivering concise oral presentations is a valuable skill for nurses. Strong oral presentation skills influence not only the quality of nurse-client communications and the effectiveness of teamwork among healthcare professionals but also promotion, leadership, and professional development. This study aimed to determine the translation and psychometric evaluation of the Persian version of the oral presentation evaluation scale in nursing students.
Methodology:
The oral presentation evaluation scale (OPES) was translated into Persian using the standard method of translation and re-translation. Then, in a cross-sectional study, it was distributed among 474 nursing students of different levels using the available sampling method. Reliability was determined by Cronbach's alpha coefficient and test-retest repeatability. Confirmatory factor analyses determined construct validity.
Results
The questionnaire in Persian comprises 15 items and is divided into three factors: accuracy of content, effective communication, and speech clarity. The overall content validity index score (S-CVI) was 0.94. The three-factor questionnaire's fitness indices were RMSEA = 0.070, CFI = 0.96, GFI = 0.91, and AGFI = 0.88. The intra-cluster correlation index (ICC) was 0.965, and the Cronbach's alpha was 0.875.
Conclusion
The results of the present study indicated that the OPES-Persian Survey with 15 items enjoyed appropriate reliability and validity and could be used to evaluate the successful oral presentation among nursing students.
Exploring the Role of Disulfidptosis-Related Genes in GBMLGG Prognosis: A Comprehensive Pan-Cancer Study
Authors: Shen Jing , Li Xiaowei , Xu Hua , Wang Peng , Yan Hanfei 
Published: February 2024

Abstract
Background
Disulfidptosis, a novel programmed cell death (PCD) driven by disulfide stress, has emerged as a potential player in various cancer dynamics. However, its implications in Glioma (GBMLGG) prognosis and immunotherapy response remain an uncharted territory.
Results
An extensive analysis on 15 disulfidptosis-associated genes across multiple cancers highlighted their diverse prognostic values. Specifically for GBMLGG, these genes offered unique non-clustered grouping with profound significance in prognosis differentiation. Out of these, seven pivotal genes were pinpointed using a robust machine learning framework encompassing 101 algorithm combinations. Their prognostic reliability was underscored through receiver operating characteristic curves and Kaplan-Meier (KM) analyses, both presenting highly satisfactory outcomes. The culmination of this work led to the formulation of a predictive nomogram. In-depth correlations were established between these target genes and key tumor-immunity factors, with 13 types of immune cells and 19 immune checkpoint genes showcasing significant ties. Single-cell analysis provided further validation to these findings.
Conclusions
This study underscores the intricate relationship between disulfidptosis-associated genes and GBMLGG prognosis. The derived nomogram, based on meticulously selected target genes through machine learning, exhibited remarkable accuracy across different datasets, offering promising avenues for GBMLGG prognostic strategies.
Trial registration:
Not applicable
Limited training and transfer effects in older and young adults who participated in 12 sessions of process-based working memory training. A three-armed pretest-posttest design study
Authors: Zając-Lamparska Ludmiła 
Published: February 2024

Abstract

Objective: Numerous studies confirm the effectiveness of cognitive training in older adults. However, there is limited evidence of the transfer occurrence. The part of the study presented here tested the effect of 12 sessions of process-based working memory training on the performance of the trained task (training effect) and other cognitive tasks (transfer effect). A pretest-posttest study design with one experimental group and two control (passive and active) groups was applied. The sample comprised 3 groups of older adults: experimental (n = 25), passive control (n = 22), active control (n = 7), and young adults: experimental (n = 25), passive control (n = 25), and active control (n = 12). The study was registered after completion of the study with a ClinicalTrials.gov Identifier: NCT06235840 on 31 January 2024.
Results: Under the influence of training, the performance of the trained task improved significantly, but only in young adults. Transfer of WM training effects was not revealed. Among young adults, a testing effect was observed for the indicator of attentional focus and psychomotor speed. Moreover, the obtained results suggest the transfer from practice in multi-domain training, implemented in the active control group, to tasks that require the use of fluid intelligence. However, this finding should be interpreted with great caution due to the small size of active control groups.
Mineral and Fluid Transformation of Hydraulically Fractured Shale: Case Study of Caney Shale in Southern Oklahoma
Authors: Awejori Gabriel A. , Dong Wenming , Doughty Christine , Spycher Nicolas , Radonjic Mileva 
Published: February 2024

Abstract

This study explores the geochemical causes of permeability loss in hydraulically fractured reservoirs. The experiments involved the reaction of powdered-rock samples with produced brines in batch reactor system at temperature of 95oC and atmospheric pressure for 7-days and 30-days respectively. Results show changes in mineralogy and chemistry of rock and fluid samples respectively, therefore confirming chemical reactions between the two during the experimental period. The shift in mineralogy of the rock included decreases of pyrite, feldspar, and carbonate content whiles illite content showed an initial increase before decreasing. Results from analyses of post-reaction fluids generally corroborate the results obtained for mineralogical analyses. In essence, the results reveal a complex trend of reactions between rock and fluid samples which is summarized as follows. Breakdown and oxidation of pyrite by oxygenated fluid causes transient and localized acidity which triggers the dissolution of feldspar, carbonates, and other minerals susceptible to dissolution under acidic conditions. The dissolution of minerals releases high concentrations of ions which subsequently precipitate secondary minerals. On the field scale, the formation of secondary minerals in the pores and flow paths of hydrocarbons significantly reduces the permeability of the reservoir, which culminates in rapid productivity decline. This study provides an understanding of the geochemical rock-fluid reactions that impact long term permeability of shale reservoirs. Findings from the study also reveal the potential of depleted hydraulically fractured shale reservoirs as carbon storage units.