bluuebunny/crossref_metadata_2025_split huggingface dataset:
Catheter placement by the nephrologist: a safe and effective method for improving access to peritoneal dialysis
Authors: lafrid maria , abdelaali bahadi , labioui narjiss , hanine ismail , laasli hajar , mponguili theresia peya , hallak mohammed , benbria sanae , kabbaj driss el 
Published: February 2024

Abstract

Introduction:
Peritoneal dialysis (PD) is as effective as hemodialysis and provides a better quality of life. However, it remains underused, particularly in our country. The aim of our study was to evaluate the impact of catheter placement by the nephrologist on the incidence of peritoneal dialysis patients, compare the success rates and assess the short- and long-term complications between surgical and nephrologist placements.
Methods
retrospective study of 69 patients with PD from January 2008 to December 2022.
Results
28 received PD catheter placement by nephrologists (group A), while 41 underwent the procedure performed by urologists (group B).The incidence of patients placed on PD has shown a significant increase since the initiation of catheter placement by nephrologists, with a growth rate of over 100% every two years. No significant difference was observed in the incidence of short-term mechanical and infectious complications between the two groups. However, the group B experienced a higher occurrence of long-term mechanical and infectious complications compared to the group A. The waiting time before catheter placement was significantly shorter in group A (5 days vs. 20 days; p < 0.001). The success rate of peritoneal dialysis catheter placement in group A was 92.85%, while it was 97.56% in group B. There was no significant difference in catheter survival at 1 year between the two groups. However, the mean catheter survival was significantly longer in group B (17 months vs. 11 months, p = 0.026).
Conclusion
The placement of the PD catheter by nephrologists has demonstrated effectiveness and safety.
Effect of crown seating methods on the remnant cement in the subgingival region of the cement- retained implant crown
Authors: Ji Fanghui , Hwiseong Oh , Lee Jeongyol , Ryu Jae Jun , Shim Ji Suk 
Published: February 2024

Abstract

This study aimed to investigate the effects of crown seating speed, crown seating force, quantity of cement used, and type of implant cement on the amount of RCS after cementation. Cement-retained implant crowns were cemented to titanium abutments using the following methods: four types of implant cement (TBN: Temp Bond NE®️, NR: Nexus™ RMGI, ME: Maxcem Elite™, and U200: RelyX™ U200), three quantities of cement (0.02 ml, 0.04 ml, and 0.06 ml), three crown seating speeds (5 mm/s, 10 mm/s, and 15 mm/s), and two crown seating forces (25 N, 50 N). The surface area and length of the RCS were measured using a 3D intraoral scanner. The total RCS weight was measured using an analytical balance. The RCS increased significantly as the seating speed increased, the seating force increased, and the quantity of cement increased (p < 0.05). The RCS values were the highest for TBN, followed by U200, NR, and ME (p < 0.05). The lower seating speed, smaller quantity of cement used, and smaller seating force applied in cement-retained implant restorations minimized the RCS in cement-retained prostheses. The type of cement is a factor that determines the aspects of the RCS.
Comparison of Ultrasound-Guided Single-Injection Erector Spinae Plane Block, Retrolaminar Block, and Paravertebral Block for Postoperative Analgesia in Single-Incision Video-Assisted Thoracoscopic Surgery: A Three-Arm, Double-Blind, Randomized Controlled Non-Inferiority Trial
Authors: Zhu Yuyang , Yang Yi , Zhang Qinyu , Li Xuan , Xue Wenqiang , Liu Yuan , Zhao Yufei , Xu Wenxia , Huang Jie , Fang Yu , Yan Peng , Li Shuang 
Published: February 2024

Abstract

Objective:This study aims to compare the analgesic efficacy of erector spinae plane block (ESPB), retrolaminar block (RLB), and paravertebral block (TPVB) in single-incision video-assisted thoracoscopic surgery (VATS). Additionally, ESPB and RLB are investigated as potential secondary options in cases where TPVB is contraindicated or unsuccessful.Methods：A total of 76 patients underwent general anesthesia induction followed by nerve block under ultrasound guidance, with 20 ml of 0.5% ropivacaine administered to each. Recorded parameters included NRS scores' AUC during rest and coughing over the first 24 postoperative hours, preoperative and postoperative (24h and 48h) plasma biomarker levels, perioperative opioid consumption, time to first postoperative analgesic use, arterial blood gas analysis, white blood cell count (WBC), high-sensitivity C-reactive protein (hs-CRP), QoR-15 scores, incidence of postoperative nausea and vomiting (PONV), time to bowel function recovery, length of hospital stay (LOS), and adverse events.Results:The AUC for Group E (107.8±10.53) and R (104.8±8.05) compared to P (103.6±10.42) had differences of 4.2±3.0 (95% CI -1.82 to 10.22) and 1.2±2.6 (95% CI -3.97 to 6.37), respectively, with lower limits of the 95% confidence interval (CI) exceeding the non-inferiority margin. IL-6, IL-8, IL-1β, TNF-α at 24 and 48h postoperatively showed no significant differences. At 24h, IL-10 levels were comparable, and at 48h, group T exhibited higher IL-10 levels than group E. There were no statistical differences in QoR-15 scores, perioperative opioid consumption, time to first postoperative analgesic use, WBC, hs-CRP, Glu, and Lac levels, time to bowel function recovery, and LOS (P>0.05). The time from block completion to incision showed no statistical differences (P=0.996), but four cases in Group E experienced hypertension during incision, one in Group R, and none in Group P (P=0.047). Regarding adverse events, one patient each in Groups P and R experienced hypotension, while no patients in Group E experienced hypotension (P=0.142). No cases of PONV or other complications were observed.Conclusion:ESPB and RLB can provide analgesic effects for VATS patients that are non-inferior to TPVB, with the added benefit of improved safety. They represent effective alternative options to TPVB.Trial registration:Chinese Clinical Trial Register (identifier: ChiCTR2300069985).
Challenges in Modern Contraception Access among Married Bonda Women: Insights from a Qualitative Study on Family Planning Barriers and Healthcare Dynamics
Authors: Nayak Ranjita , Kaushal Sonia , Sharma A.N. 
Published: February 2024

Abstract

Background
Family planning practices play a crucial role in avoiding unintended pregnancies and the preventable mortality associated with childbirth that occurs either ‘too soon’ or ‘too frequently.’ These practices significantly influence the health outcomes of mothers, newborns, and children.
Aim
This research aims to conduct a qualitative investigation to gain a comprehensive understanding of the existing barriers related to modern family planning methods, along with contraceptive use, the management of unwanted pregnancies, and spacing between two children. Also, the study examines the influence of healthcare providers, mothers/mothers-in-law, and husbands on family planning practices within the Bonda tribe in the Malkangiri district of Odisha, India.
Methods
Utilizing a qualitative method, the investigation incorporated 8 Focus Group Discussions, 7 In-depth Interviews, and insights from 16 key informants.
Results
Thematic analysis was employed to reveal instances of unconsented contraceptive procedures, reproductive health complications, and challenges in contraception methods: unraveling societal dynamics and cultural barriers impacting family planning practices among Bonda women.
Conclusions
The study highlights the crucial need for enhanced maternity care and underscores the importance of culturally sensitive services. Furthermore, it promotes provider training to ensure satisfaction, equity, and professionalism in care childbirth for tribal women. The findings strongly indicate that addressing these issues can potentially enhance family planning outcomes among the Bonda tribe.
Continuum of care pathway for maternal healthcare in India: analysis of trends, dropouts, and determinants from 2015 to 2021
Authors: Longchar Wapangjungla , Kodali Prakash Babu , Hense Sibasis 
Published: February 2024

Abstract

This study examined the trends of maternal continuum of care (CoC) across antenatal (ANC), intranatal and postnatal care (PNC) using NFHS-4 to NFHS-5 data and analysed the associated factors in its utilisation employing Anderson’s health services utilisation model in Indian context. A total of 190,898 and 176,877 women aged 15–49 years who had a live birth in the 5 years preceding the surveys [NFHS-4 and NFHS-5] were included respectively. Binary logistic regression identified the need, pre-disposing and enabling factors of CoC pathways. The overall progress of CoC completion was 11.3 points from NFHS-4 (38.7%) to NFHS-5 (50.0%). The largest dropout in CoC was observed in ANC followed by PNC. Odds of completing CoC was higher among women aged 25–34 (AOR:1.18; 95% CI: 1.09–1.27), with higher education (AOR:1.74; 95% CI: 1.58–1.92), from urban (AOR:1.09; 95% CI:1.01–1.19), richer household (AOR: 1.42; 95% CI: 1.29–1.56), southern region (AOR: 2.13; 95% CI: 1.89–2.40), exposed to mass media (AOR:1.51; 95% CI: 1.39–1.65), and covered by health insurance (AOR: 1.24; 95% CI: 1.15–1.35). Policy addressing the barriers inhibiting CoC completion especially in ANC and PNC stages are important. Context specific multisectoral approaches involving family, community, and health system may be warranted especially in low-performing states.
Building capacity to conduct genetic epidemiology research on hyperuricaemia and gout in an Indigenous community in Guam
Authors: Paulino Yvette C. , Camacho Frank , Paulino Tristan VC , Lee Delores J. , Natividad Lisa Linda , Matisoo-Smith Elizabeth , Merriman Tony R. , Gosling Anna 
Published: February 2024

Abstract

Background
Gout, the most common inflammatory arthritis disease, and hyperuricaemia onset are influenced by environmental and genetic factors. We sought to investigate these factors in an Indigenous community in Guam.
Methods
In this cross-sectional study, the University of Guam led the qualitative inquiry with the native community, training (pre-screening of participants, data collection methods, and biospecimen handling), study implementation (outreach and recruitment, data collection, and DNA extraction and quantification), and qualitative and epidemiologic data analyses. Recruitment targets were based on demographic representation in current census data. The University of Otago collaborated on ethics guidance, working with Indigenous communities, and led the genetic sequencing and genetic data analysis. Participants were recruited in Guam from Fall 2019 to Spring 2022.
Results
Of the 359 participants, most self-identified as Native CHamorus (61.6%) followed by Other Micronesians (22.0%), and Filipinos (15.6%). The prevalence of metabolic conditions from highest to lowest were obesity (55.6%), hyperuricaemia (36.0%), hypertension (27.8%), gout (23.0%), diabetes (14.9%), cardiovascular disease (8.4%), kidney disease (7.3%), and liver disease (3.4%). Compared to Filipinos and Other Micronesians, significantly more CHamorus had hyperuricaemia (42.1% versus 26.8% in Filipinos and 25.3% in Other Micronesians), gout (28.5% versus 21.4% and 8.9%), diabetes (19.5% versus 8.9% and 6.3%), and hypertension (33.9% versus 19.6% and 16.5%).
Conclusions
We estimated the prevalence of metabolic conditions, especially gout and hyperuricaemia, and found statistical differences among major ethnic groups in Guam, all while obtaining the Indigenous community’s feedback on the genetic study and building gout research capacity. The results of ongoing genetic sequencing will be used to understand molecular causes of gout in Guam.
Relevance of red blood cell Lithium concentration in the management of Lithium-treated bipolar and unipolar disorders: a systematic narrative review
Authors: COYAC MANON , JALABERT LYNN , DECLEVES XAVIER , ETAIN BRUNO , BELLIVIER FRANK 
Published: February 2024

Abstract

Background: Despite a variability in response and a narrow therapeutic index, lithium remains the gold standard treatment for bipolar disorders (BD), and a treatment of choice for non-bipolar mood disorders (MD). To date, the relevance of red blood cell (RBC) lithium monitoring remains unclear in the management of MD.
This systematic review aims to provide a summary of areas in which the interest of lithium concentration monitoring was explored in the literature, and to discuss the relevance of such monitoring in the management of lithium-treated individuals.
Methods: We conducted a systematic review, based on preferred reporting items for systematic reviews and Metanalysis (PRISMA) guidelines, of articles published between 1973 and February 2023, indexed in the following databases: EMBASE, MEDLINE, Cochrane Library. The search terms were combinations of the following headings: “Lithium AND Plasma AND Erythrocyte AND Mood disorders”. The systematic review protocol was published to PROSPERO (CRD42023406154).
Results: Out of the 252 identified studies, 57 met the selection criteria. These studies primarily investigated the measurement of Red Blood Cell lithium concentration (RBCLC) in various areas: compliance (5 articles), SE/toxicity (13 articles), prediction of lithium response/therapeutic efficacy (17 articles), differences according to the type of MD (18 articles) and to the polarity of mood episodes (10 articles), associated clinical and socio-demographic factors (33 articles), and potential pathophysiological mechanisms (30 articles). The heterogeneity in methods and results, coupled with the limited amount of data, precludes any firm conclusion regarding the relevance of measuring RBCLC. However, the literature indicates a potential association between RBCLC and side effects (SE), particularly neurotoxicity. Surprisingly, the relevance of monitoring RBCLC is yet to be conclusively demonstrated, and its indications still require to be specified. In this context, we propose avenues of research aimed at exploring the relevance of measuring RBCLC.
Conclusions: Despite decades of research on lithium, the relevance of monitoring RBCLC in the management of MD remains unclear. This underscores the imperative for high-quality research involving large representative samples.
Production of rare ginsenosides by biotransformation of Panax notoginseng saponins using Aspergillus fumigatus
Authors: Yang Lian , Lin Dongmei , Li Feixing , Cui Xiuming , Lou Dengji , Yang Xiaoyan 
Published: February 2024

Abstract
Panax notoginseng saponins (PNS) are the main active components of Panax notoginseng. But after oral administration, they need to be converted into rare ginsenosides by human gut microbiota and gastric juice before they can be readily absorbed into the bloodstream and exert their effects. The sources of rare ginsenosides are extremely limited in P. notoginseng and other medical plants, which hinders their application in functional foods and drugs. Therefore, the production of rare ginsenosides by the transformation of PNS using Aspergillus fumigatus was studied in this research. During 50 days at 25 ℃ and 150 rpm, A. fumigatus transformed PNS to 14 products (1–14). They were isolated by varied chromatographic methods, such as silica gel column chromatography, Rp-C18 reversed phase column chromatography, semi-preparative HPLC, Sephadex LH-20 gel column chromatography, and elucidated on the basis of their NMR and MS spectroscopic data. Then, the transformed products (1–14) were isolated and identified as ginsenosides C-K, 20 (R/S)-Rg3, Rg5, 20 (R)-Rh1, Rk1, Rh4, Rk3, 20(S)-protopanaxatriol, 20(S)-I, 20 (R/S)-Rg2, and notoginsenosides 20 (R/S)-R2, respectively. In addition, all transformed products (1–14) were tested for their antibacterial activity. Among them, compounds 5 and 7 showed moderate antibacterial activities against Staphylococcus aureus and Candida albicans with MIC values of 6.25/25.00, and 1.25/25.00 µg/mL, respectively. This study lays the foundation for production of rare ginsenosides.
Dapagliflozin attenuates LPS-induced myocardial injury by reducing ferroptosis
Authors: Hu Ke , Jiang Pin , song Bing , Hou Ya , Gu Qianyu , Guo Meng , Peng Ningxin , Chen Jiayu , Zhao Jinxuan , Chen Haiting , Xie Jun 
Published: February 2024

Abstract

Lipopolysaccharide induces sepsis in vivo, with a significant proportion of septic patients progressing to septic cardiomyopathy. Previous studies have reported the involvement of ferroptosis in the pathogenesis of septic cardiomyopathy. SGLT2 inhibitors such as dapagliflozin have been demonstrated to have cardioprotective effects, with reports indicating a reduction in myocardial ischemia-reperfusion injury through the attenuation of ferroptosis. However, the role of ferroptosis-induced myocardial injury in the context of LPS-induced sepsis remains unclear. Therefore, our study aims to investigate the therapeutic effects of dapagliflozin on LPS-induced iron-overload cardiac injury. Our results indicate that dapagliflozin inhibits the translation of key proteins associated with ferroptosis, including GPX4, FTH1, and SLC7A11, while reducing the transcription of lipid peroxidation-related mRNAs PTGS2 and ACSL4, as well as iron metabolism genes TFRC and HMOX1. Additionally, both compounds alleviate potential mitochondrial membrane damage. Furthermore, dapagliflozin has been shown to mitigate LPS-induced cardiac injury burden. Based on these findings, we conclude that dapagliflozin can alleviate LPS-induced iron dysregulation-mediated cardiac dysfunction, expanding the clinical indications for SGLT2 inhibitors.
Evaluate the potential of permeable pavement for urban runoff reduction
Authors: Cai Qingchi , Lin Jenyang , Chen Chifeng 
Published: February 2024

Abstract

Permeable pavement (PP) is one of the widely adopted low-impact development measures in construction for enhancing urban water retention capacity, which has received increasing attention. To assess the performance of PP in surface runoff management, a comprehensive study involving hydrological monitoring and simulation was conducted at a site in Taipei. In the hydrological monitoring phase, data from 41 effective rainfall events were collected, providing a robust dataset for the analysis of PP effects. Subsequently, six distinct PP implementations and four varied rainfall scenarios were meticulously designed and simulated using the Storm Water Management Model (SWMM). The results showed that (1) PP implementation contributes to mitigating surface runoff in the study site. The observed reduction in surface runoff spans a significant range, from 5–30.8%, with an average runoff reduction rate of approximately 14.6% for each effective rainfall event. (2) With an increasing rainfall return period, the percentage reduction of total and peak runoff decreases. The marginal control on both total and peak runoff decreased with increasing levels of PP implementation. (3) PP measures in reducing peak runoff flow and the time of arrival of peak runoff flow were relatively weak. (4) A new indicator was defined to characterize the cost-effectiveness of project construction, which helps in project management.
Quantum phase transitions in one-dimensional nanostructures: a comparison between DFT and DMRG methodologies
Authors: Pauletti T. , Sanino M. , Gimenes L. , Carvalho I. M. , França V. V. 
Published: February 2024

Abstract

Context: In the realm of quantum chemistry, the accurate prediction of electronic structure and properties of nanostructures remains a formidable challenge. Density Functional Theory (DFT) and Density Matrix Renormalization Group (DMRG) have emerged as two powerful computational methods for addressing electronic correlation effects in diverse molecular systems. We compare ground-state energies (e0), density profiles (n) and average entanglement entropies ($\bar S$) in metals, insulators and at the transition from metal to insulator, in homogeneous, superlattices and harmonically confined chains described by the fermionic one-dimensional Hubbard model. While for the homogeneous systems there is a clear hierarchy between the deviations, $D%(\bar S)<D%(e_0)< \bar D%(n)$, and all the deviations decrease with the chain size; for superlattices and harmonical confinement the relation among the deviations is less trivial and strongly dependent on the superlattice structure and the confinement strength considered. For the superlattices, in general increasing the number of impurities in the unit cell represents less precision on the DFT calculations. For the confined chains, DFT performs better for metallic phases, while the highest deviations appear for the Mott and band-insulator phases. This work provides a comprehensive comparative analysis of these methodologies, shedding light on their respective strengths, limitations, and applications.
Methods: The DFT calculations were performed using the standard Kohn-Sham scheme within the BALDA approach. It integrated the numerical Bethe-Ansatz (BA) solution of the Hubbard model as the homogeneous density functional within a local-density approximation (LDA) for the exchange-correlation energy. The DMRG algorithms were implemented using the ITensor library, which is based on the Matrix Product States (MPS) ansatz. The calculations were performed until the energy reaches convergence of at least 10-8.
Health-related behaviors of adult male cancer survivors in Korea: A propensity score matching analysis of data from the Korean National Health and Nutrition Examination Survey VII-VIII (2016– 2021)
Authors: Jung Hyein , Choi Yoonjoo , Kim Byungmi 
Published: February 2024

Abstract

Purpose
Studies that have compared the overall health behaviors of male survivors of cancer and the population without cancer in South Korea are limited. Therefore, we aimed to compare the quality of life and health-related behaviors of cancer survivors and the population without cancer in South Korea.
Methods
This cross-sectional, matched case-control study recruited Korean males aged 19–80 years from the Korea National Health and Nutrition Examination Survey (KNHANES) VIII. Of the 11,760 participants, 349 cancer survivors and 1,047 controls without cancer were matched by 1:3 propensity score matching using age, cohabitation, household income, education level, employment status, type of job, and private insurance. Height, weight, smoking status, drinking status, and physical activity status were also recorded.
Results
The cancer survivors had lower odds of being overweight and higher odds of being former smokers and drinkers than the controls after adjusting for potential confounders. The cancer survivors and controls showed no significant differences in physical activity or food consumption. No significant differences were noted among the young adults. However, the middle-aged and older male cancer survivors were more likely to be overweight and obese, respectively. The middle-aged survivors were also more likely to be former smokers, while the older survivors were more likely to be former drinkers.
Conclusion
The cancer survivors were more likely to have a normal weight, be past smokers, or be former drinkers. Education on cancer prevention is required to improve health-related behaviors and prevent secondary cancer.