bluuebunny/crossref_metadata_2025_split huggingface dataset:
Akumulasi Logam Berat Cu Dan Hg pada Mangrove Rhizopora mucronata di Pantai Timur Surabaya (Pamurbaya)
Authors: Mahmiah Mahmiah , Sa'adah Nor , Kisnarti Engki Andri , Millenia Fachrani Vebranti 
Published: November 2023

Cemaran logam berat seperti Cu dan Hg di Pantai Timur Surabaya (Pamurbaya) dikhawatirkan memberikan dampak terhadap kualitas perairan. Mangrove yang tumbuh di Pamurbaya dapat digunakan sebagai indikator cemaran logam berat. Kemampuan mangrove dalam mengakumulasi logam berat ditunjukkan melalui nilai bioakumulasi (BAF), biokonsentrasi (BCF), dan translokasi faktor (TF). Salah satu mangrove yang terdapat di Pamurbaya adalah R.mucronata. Mangrove inimemiliki akar penyangga, selain fungsinya untuk membantu tegaknya pohon, akar jenis ini juga dapat menahan dan memantapkan sedimen tanah, sehingga mencegahtersebarnya bahan pencemar ke area yang lebih luas. Penelitian ini bertujuan untuk mengidentifikasi bioakumulasi cemaran logam berat Cu dan Hg pada mangrove R. mucronata, air, dan sedimen di Pantai Timur Surabaya. Sampel penelitian diambil pada tiga lokasi melalui purposive sampling. Analisis logam berat Cu dan Hg menggunakan metode Atomic Absorption Spectroscopy (AAS) dan parameter fisika-kimia oseanografi diukur secara in situ dengan pengulangan sebanyak 3 kali. Hasil penelitian menunjukkan kadar logam berat Cu pada air lebih tinggi dibandingkan sedimen berturut-turut Stasiun 1>Stasiun 2>Stasiun 3. Hasil cemaran logam Hg pada mangrove R. mucronata, air dan sedimen menunjukkan nilai di bawah baku mutu dengan kisaran 0,0004< Hg<0,0006 ppm. Berdasarkan perhitungan nilai bioconcentration factor (BCF) dan translocation factor (TF), diketahui bahwa kemampuan mangrove R.mucronata sebagai tumbuhan excluder dan fitoekstraksi sehingga mampu mengurangi polutan logam berat dari lingkungan melalui proses penyerapan melalui akar dan translokasi menuju daun.
Evaluación de la sustentabilidad en espacios rurales relacionados con el ecoturismo. estudio de caso en la selva Lacandona, Chiapas, México
Authors: Zarazúa José Alberto , Mazabel Davison , Moncayo Estrada Rodrigo , Rendón Medel Roberto 
Published: November 2023

Esta investigación realiza una evaluación ex-post de la sustentabilidad en espacios rurales relacionados con el ecoturismo, centrada en un estudio comparativo de tres empresas enclavadas en la Reserva de la Biosfera Montes Azules (REBIMA) y una empresa más ubicada fuera de ella, todas en el municipio de Ocosingo, Chiapas, México. 75% de los entrevistados son hombres con edad promedio de 36 años, siete años de escolaridad y 1,9 hectáreas. La principal fuente de ingresos es el ecoturismo, que presenta una relación beneficio-costo venida a menos de 2,7 a 1,7, entre 2007 y 2011, respectivamente. La evidencia indica un desequilibrio en el acceso a subsidios, donde la pertenencia étnica desempeña un rol trascendental.
Acciones colectivas y recursos naturales en conflicto. Historia ambiental de luchas urbanas por agua y sierras en Tandil, Argentina
Authors: Guerrero Elsa Marcela , Wagner Lucrecia Soledad , Rodríguez Corina Iris , Sosa Beatriz Soledad 
Published: November 2023

En el municipio de Tandil, diferentes expresiones socioambientales han tenido lugar a nivel local en las últimas décadas. Algunas de estas acciones responden a los efectos ambientales de ciertas actividades –la minería, la instalación de actividades contaminantes, la lucha urbana por el acceso a la tierra, al agua y a mejores condiciones ambientales, la problemática de los residuos sólidos urbanos e industriales y otros reclamos de justicia ambiental–. El presente trabajo discute desde una perspectiva teórica y mediante el análisis empírico de ciertos casos, las principales consideraciones epistemológicas asociadas a conceptos centrales que permiten entender y explicar el accionar social frente a la lucha ambiental. Por ello, interesa identificar ciertas problemáticas, describiendo los conflictos y las acciones colectivas de las luchas urbanas que reclaman mejoras en las condiciones ambientales a nivel local. El objetivo del presente trabajo es situar determinadas acciones colectivas en espacio y tiempo. Para ello se analizan cuatro casos de luchas urbanas suscitados por dos recursos naturales en pugna: el paisaje serrano y el recurso hídrico subterráneo.La selección del estudio de caso como método de investigación responde al carácter exploratorio del tema abordado. La inferencia lógica inductiva favorece la identificación de las categorías de análisis más propicias para su abordaje y pone en evidencia formas de organización, estrategias colectivas, y respuestas frente a los reclamos. Se emplean como técnicas de producción de conocimiento: la comparación, la observación documental –periódicos locales, sitios Web, archivos públicos y privados– y entrevistas a informantes calificados. En todos los casos bajo análisis las luchas se enmarcan en un contexto de crisis del Estado como proveedor de espacios de participación que favorecen la legitimación de nuevos espacios para el reclamo socioambiental. En particular cada caso presenta singularidades y generalidades que son posibles identificar y describir.
Estado de cosas inconstitucional en el caso del derecho a la alimentación de la población de La Guajira. Argumentos de la interpretación por parte de la Corte Constitucional de Colombia
Authors: Terreros Calle Fernando Carlos 
Published: November 2023

En Colombia, de conformidad con el artículo 374, la Constitución Política podrá ser reformada por el Congreso mediante un acto legislativo, por una asamblea constituyente o por el pueblo mediante referendo; sin embargo, la Corte Constitucional realiza actos de construcción jurídica cuya consecuencia es una mutación en la Constitución a través de la creación de normas implícitas como es el caso del estado de cosas inconstitucional, que da lugar al establecimiento de una nueva regla constitucional. Lejos de considerar que la interpretación del derecho es abiertamente discrecional o que, como lo manifiestan algunos autores (Suárez-Parra, 2007; López, 2011), la Corte Constitucional colombiana “legisle” o genere inseguridad jurídica, la creación de derecho en sede interpretativa es algo que no genera incompatibilidad con nuestra cultura jurídica, tal como lo indican Kelsen (1982), Tarello (2013) y Gómez (2018). La tesis planteada consiste en comprobar que los argumentos de la interpretación de la Corte corresponden con la teoría del escepticismo interpretativo del realismo genovés, aplicado a la figura de declaratoria de estado de cosas inconstitucional, cuyo fin es proteger los derechos fundamentales de la población Wayúu en La Guajira, especialmente el derecho a la alimentación en las sentencias de la Corte Constitucional de Colombia (T-302 de 2017, T-359 de 2018).
Lapidários
Authors: Marquéz-Elul Fercho 
Published: November 2023

Este artigo reflete o processo em andamento do projeto artístico Lapidários: uma sessão expositiva e reprodutiva das pedras, em especial, o deslocamento de um acervo constituído privadamente, uma seção da biblioteca, de publicações de artistas e de autores do campo das humanidades tendo a pedra e suas interlocuções com outros campos para o espaço de exposição, uma sessão expositiva, em junho de 2022, da Pinacoteca Barão de Santo Ângelo em Porto Alegre, contando com a interação dos visitantes, bem como uma encontro com artistas que doaram ao projeto publicação. Valendo como base teórica reflexões sobre a biblioteca de Georges Perec, o colecionismo segundo Walter Benjamin, bem como a histografia da mesa através de Leo Steinberg, Georges Didi-Huberman, Yves Alain-Bois e Rosalind Krauss e poéticas como as de Rachel Whiteread e Robert Rauschenberg, objetiva, a partir da sessão expositiva ocorrida, refletir brevemente sobre a organização e o locus em que uma biblioteca se instala e mais detidamente sobre a mesa como dispositivo de apresentação e exposição do conhecimento sobre pedras condensado a partir de ínumeros exemplares impressos e entre si postos em articulação, bem como as questões de horizontalidade que permeia as produções contemporâneas e a visualidade da imagem.
HIF-1α/MMP-9 Axis Is Required for the Early Phases of Skeletal Myoblast Differentiation under Normoxia Condition In Vitro
Authors: Chellini Flaminia , Tani Alessia , Parigi Martina , Palmieri Francesco , Garella Rachele , Zecchi-Orlandini Sandra , Squecco Roberta , Sassoli Chiara 
Published: November 2023

Hypoxia-inducible factor (HIF)-1α represents the oxygen-sensitive subunit of HIF transcriptional factor, usually degraded in normoxia and stabilized in hypoxia to regulate several target gene expression. Nevertheless, in the skeletal muscle satellite stem cells (SCs), an oxygen level-independent regulation of HIF-1α has been observed. Although HIF-1α has been highlighted as SC function regulator, its spatio-temporal expression and role during myogenic progression remain controversial. We herein analyzed HIF-1α expression and localization in differentiating murine C2C12 myoblasts and SCs under normoxia and evaluated matrix metalloproteinase (MMP)-9 as a HIF-1α target, by biomolecular, biochemical, morphological and electrophysiological analyses. HIF-1α expression increased after 24/48 h of differentiating culture and tended to decline after 72 h/5 days. Committed and proliferating mononuclear myoblasts exhibited nuclear HIF-1α expression, differently from the more elongated and parallel-aligned cells, likely ready to fuse with each other, which show mainly a cytoplasmic localization of the factor. Multinucleated myotubes displayed both a nuclear and cytoplasmic HIF-1α expression. The MMP-9 and MyoD (myogenic activation marker) expression synchronized with that of HIF-1α, increasing after 24 h of differentiation. Short-interfering RNA silencing of HIF-1α and MMP-9 and MMP-9 pharmacological inhibition unraveled MMP-9 as HIF-1α downstream effector and HIF-1α/MMP-9 axis essential for the morpho-functional cell myogenic commitment.
LA CREATIVITÀ DELLE FOTOGRAFIE ON-LINE ALLA LUCE DELLA NUOVA DIRETTIVA 790/2019
Authors: Trerè Bianca 
Published: November 2023

Il complesso normativo che regola la materia (essenzialmente le direttive n. 2019/790 sul diritto d’autore e sui diritti connessi nel mercato unico digitale e n. 2001/29 sull’armonizzazione di taluni aspetti del diritto d’autore e dei diritti connessi nella società dell’informazione) presenta confini labili e mutevoli, al punto che le autorità giudiziarie statali e comunitarie sono chiamate non solo a dirimere controversie, ma anche a fornirne l’interpretazione: una valutazione normativa aggravata dalla circostanza per cui i giudici sono chiamati a pronunciarsi non solo sugli elementi giuridici quanto nell’ambito di una vera fase di “politica del diritto”. In un contesto del genere il vero elemento innovativo di cui deve tenere conto l’interprete è rappresentato da fattori umani, quali la modifica della percezione del tempo e della realtà che creano una potenziale frattura fra ambito normativo e sociale.
El Anteproyecto de Código Mercantil en sus previsiones sobre las cartas de patrocinio
Authors: Espigares Huete José Carlos 
Published: November 2023

Todo el mundo sabe lo que son las “cartas de patrocinio”: y nadie sabe lo que son. No se nos ocurre mejor fórmula para expresar una realidad ciertamente desconcertante. El caso es especialmente comprometido porque la relevancia práctica de tal desconcierto es muy significativa y con efectos que van más allá de nuestras fronteras. Dos nuevas resoluciones han despertado el interés por la cuestión pretérita (STS de 28 de julio de 2015, RJ\2015\4899 y STS de 26 de diciembre de 2014, RJ\2014\6828).
Los periodos limitados en la nueva normativa de abuso de mercado
Authors: Enrique García Lázaro 
Published: November 2023

La entrada en vigor, el 3 de julio del pasado año, del Reglamento Europeo de Abuso de Mercado (Reglamento n° 596/2014 del Parlamento Europeo y del Consejo, de 16 de abril de 2014, sobre el abuso de mercado; en adelante, por sus siglas en inglés, “MAR”) trajo consigo la imposición de nuevas obligaciones a las sociedades cotizadas en materia de prevención del abuso de mercado.
Digital divide and bilateral trade in Africa
Authors: MIGNAMISSI DIEUDONNE , Bio Issa 
Published: November 2023

Abstract
This paper contributes to the literature on the discussed effects of digitization on bilateral trade in African countries over the period 1995-2021. We proceed in two steps. In the first, we calculate, following an absolute and bilateral approach, original digital divide indicators relating to fixed phone, cell phone, internet and broadband. In a second step, we link the calculated indicators to measures of bilateral trade (bilateral exports, bilateral imports and total bilateral trade). Given the characteristics of the data, we apply the Poisson Pseudo Maximum Likelihood (PPML) estimator. Subsequently, we deepen the empirical investigations by disaggregating the effect of the digital divide on bilateral exports and imports, estimating the effect of the bilateral digital divide (including the sign of the gap) on bilateral trade, further controlling for omission bias despite accounting for multilateral resistances, using several estimators competing with PPML, further controlling for fixed effects and multilateral resistances with Poisson Pseudo-Maximum Likelihood Regression with High Dimensional Fixed Effects, controlling for endogeneity with IV-Poisson regression, then by addressing the issue of uncertainty in the model using several Bayesian techniques. Taken together, these techniques led us to the key finding that the digital divide is a limiting factor for bilateral trade in Africa. In other words, the distance of countries from complete digital coverage or digital inequalities between countries, is an obstacle to bilateral trade in Africa. This is due to high transaction costs, complex and cumbersome administrative and commercial procedures between countries, and poor digital and physical connectivity between countries, among other things. These different situations tend to lengthen the distance between countries, reinforcing the border effect, all of which contribute to reducing the intensity of trade between countries. The various sensitivity and robustness tests corroborate this main result.
Predictive models for live birth outcomes of FET: Improving clinical decision-making based on machine learning analysis
Authors: Hu Xinyue , Wang Xuejiao , Xia Mingjing , Ding Yubin , Li Tian , Zhong Zhaohui , Wang Mao , Zhong Hucen , Wan Qi , Tang Xiaojun 
Published: November 2023

Abstract
Purpose: This study used multiple machine learning algorithms to predict live births from frozen embryo transfers (FET) based on patient demographics, laboratory test results, and parameters associated with the FET cycle.
Methods: Data from 33,915 cycles of frozen-thaw embryo transfer performed at Chengdu Xinan Gynecological Hospital between January 2015 and December 2021 were used. The dataset was randomly divided into a training set (70%) and a test set (30%). Features were ranked for importance based on the random forest model, and features with the top 25 contribution values were used to develop logistic regression models, random forest models, support vector machine models, and XGBoost models. Shapley was used to interpret the results of the best-performing models. Receiver operating characteristic curves (AUC) under area and calibration curves were to be assessed for the performance of machine learning prediction models.
Results: Ranking the importance of features based on the stable random forest algorithm showed that the most predictive features included AMH, Basal PRL, Basal T, Basal FSH, etc. The XGBoost model had the highest AUC (0.750, 95% CI 0.746-0.755). The XGBoost-based SHAP summary plot indicated that patients with lower age, shorter years of infertility, and D5 embryo type for transfer had a greater likelihood of live birth outcome after freeze-thaw embryo transfer.
Conclusion: The XGBoost model performed best in predicting the outcome of freeze-thaw embryo transfer. The algorithm combined with the interpretability of SHAP summary plot can assist clinicians in the decision-making process of freeze-thaw embryo transfer.
Efficacy of the Mediterranean–DASH Intervention for Neurodegenerative Delay + Forest Bathing intervention in improving cognitive function and metabolic health: A single-blind, pilot randomised controlled trial
Authors: Law Pui Sze Queenie , Yau K K Katherine , Kwan Yiu Cho Rick 
Published: November 2023

Abstract

Objectives
We hypothesised that the Mediterranean–DASH Intervention for Neurodegenerative Delay (MIND) diet is effective in maintaining/enhancing cognitive function in people of Chinese ethnicity, while forest bathing (FB) can enhance the effect of the MIND diet. The objectives of this study were to examine 1) the preliminary effects of the MIND and FB interventions on the cognitive function and metabolic health of community-dwelling older adults and 2) adherence to the interventions in this population.
Design
A three-armed pilot randomised controlled trial was conducted.
Setting and Participants
We recruited community-dwelling older adults with hypertension.
Intervention
Participants were randomly allocated to three groups at a 1:1:1 ratio: 1) MIND+FB, 2) MIND diet, and 3) control group. Both the MIND+FB and MIND diet interventions lasted 12 weeks.
Measurements
The outcome measure were cognitive function, measured by the Montreal Cognitive Assessment (MoCA) and metabolic risk factors (i.e. waist circumference and fasting blood glucose) at baseline (T0), at 1 week after the completion of the intervention (T1) and at 1 week after the 3-month intervention (T2). The Friedman test was used to examine the within-group effects over the three time points in the three groups separately.
Results
Thestudy recruited 48 participants, with a median age of 76 ± 16 years and a median MoCA score of 20 ± 8. Cognitive function improved significantly overtime in the MIND+FB group (w = 0.619, p < 0.001) and the MIND diet group (w = 0.293, p = 0.009), but not in the control group. Metabolic risk factors (i.e. waist circumference and fasting blood glucose) improved significantly in the MIND+FB group from T0 to T2. The MIND dietary pattern was significantly improved in the MIND+FB group from T0 to T1. The BMI was significantly reduced from T0 to T1 in the MIND diet group. No significant between-group differences were observed in the total cholesterol, low-density lipoprotein cholesterol, triglyceride, and systolic blood pressure.
Conclusion
The MIND+FB intervention and the MIND diet promoted cognitive function and reduced some metabolic risk factors in community-dwelling older adults. These interventions have the potential to be applied in the community to prevent cognitive decline in older adults.
Using of Biosynthesized Zinc Oxide Nanoparticle and Vinegar as a Substitute of Insecticides on Vicia faba Plant
Authors: Khudhur Nashmeel Saeed , Saeed Sakar Abdulqadr , Qadr Halala Rahman , Karim Ayoub Sabir 
Published: November 2023

Abstract
The current research study includes a process of green safety method for synthesizing zinc oxide nanoparticles (ZnO NPs) from Musa paradisiaca L. leaf plant extract as an efficient chelating and capping agent for ZnO NPs from Zinc acetate dihydrate salt, and use with vinegar as a substitute of Carbaryl insecticide on Vicia faba plant. UV-Vis and FTIR studies of Musa paradisiaca L. leaf extract and ZnO NPs demonstrated that this plant is an excellent candidate for the green synthesis of ZnO NPs. From using various characterization techniques of XRD, FTIR, UV-Vis. spectroscopy and TEM, the structure, morphology, chemical composition and crystallinity of ZnO NPs were investigated. The XRD pattern spectrum and TEM, and FTIR confirmed the pure crystallinity and the spherical-shape of the hexagonal wurtzite ZnO NP structure with an average size 47 nm and with the measurement results of ZnO NPs band gap was around 4.52 eV. Seven treatments each with three replications were sprayed by the leaves including: 100 ppm ZnO NPs, 200 ppm ZnO NPs, 1% vinegar, 10% vinegar, recommended dose (1X) of Carbaryl, double dose (2X) of Carbaryl and a control (without any treatment). Following Carbaryl (2X) spraying, 100 ppm of ZnO NPs has shown the greatest effects on death rate and corrected mortality rate (Mc %) of Aphis fabae by values of 87.5% and 5.15% respectively. Moreover, 200 ppm ZnO NPs increased soil TDS and EC to 270.65 ± 0.029 ppm and 189.49 ± 0.003 µS.cm− 1 respectively. Thus, it can be concluded that the biosynthesized ZnO NPs and vinegar are good and natural substitutes of chemical pesticides.
Performance trend of the family physician referral system before and after the Covid-19 pandemic: A study in northern Iran
Authors: Soltani Seyed-Amir , Fallah Mehrdad , Marvi Aboalfazl , Naderi Malihe , Abedini Ehsan , Jahani Mohammad-Ali , Mahmoudi Ghahraman 
Published: November 2023

Abstract

Background: Considering the challenges of the referral system in the family physician program and the impact of Covid-19 pandemic on the performance of the relevant ministry's programs, it is necessary to assess the performance of the referral system. This study was conducted with the aim of investigating the performance of the family physician referral system before and after Covid-19 in Golestan province.
Objective: The present descriptive-analytical study was conducted on secondary data (including information on physicians' and midwives' visits, percentage of prescriptions and other information) in Golestan province from 2017 to 2022 in a census and retrospective manner. Data were collected using the reference ratio checklist and analyzed with SPSS 23 software at a significance level of less than 0.05.
Results: The highest and lowest percentages of referrals by family physicians were belonged to the surgical and infectious specialists before Covid-19, and internal medicine and urology specialists after Covid-19, respectively. Referral due to physician's diagnosis and target group increased compared to before Covid-19 and care and reverse referral decreased compared to before Covid-19. The amount of changes in the population covered by rural insurance, the amount of referrals to midwives, the percentage of electronic appointments after Covid-19 were significant compared to before it (P-Value<0.05).
Conclusion: The present study showed that the Covid-19 pandemic had a significant impact on family physician referral indicators, such as the process of referral to specialists, drug prescriptions, insurance coverage, one-time service population, and patient care.
Hydroxyapatite/Alginate/Polyvinyl alcohol/Agar Composite Double-Network Hydrogels as Injectable Drug Delivery Microspheres
Authors: Ghazagh Parisa , Frounchi Masoud 
Published: November 2023

Abstract
An injectable and biodegradable drug delivery system to release antibiotics at a controllable rate to treat anti-bone infection was prepared. The system was based on nanocomposites of hydroxyapatite nanoparticles (HAP) and double-network (DN) hydrogels of sodium alginate (SA)/polyvinyl alcohol (PVA) prepared in the form of microspheres embedded in injectable agar gel. The double-network hydrogels of SA/PVA were prepared by sequential crosslinking of sodium alginate with calcium ions and then PVA by freeze-thawing method. The agar gel was used as a thermos-reversible gel to facilitate injection of microspheres. The characteristics of microspheres were analyzed by FTIR, XRD, SEM and water swelling. The drug release rate of the microspheres was measured at various compositions of the delivery system components. The results showed that increase in PVA content of hydrogels led to a tighter double-network which consequently reduced the drug release rate. Loading of the drug into HAP nanoparticles as drug nano-containers, prolonged the drug release time from 1 day to 6 days when the content of HAP nanoparticles was within the range of 2.5–5%. The antibacterial activities of the drug-loaded composite hydrogels were evaluated against E. coli bacteria by disc diffusion tests showing anti-bacterial effectiveness of such drug delivery systems.