bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extreme heat and drought typical of an end-of-century climate could occur over Europe soon and repeatedly
Authors: Suarez-Gutierrez Laura , Müller Wolfgang A. , Marotzke Jochem 
Published: November 2023

AbstractExtreme heat and drought typical of an end-of-century climate could soon occur over Europe, and repeatedly. Despite the European climate being potentially prone to multi-year successive extremes due to the influence of the North Atlantic variability, it remains unclear how the likelihood of successive extremes changes under warming, how early they could reach end-of-century levels, and how this is affected by internal climate variability. Using the Max Planck Institute Grand Ensemble, we find that even under moderate warming, end-of-century heat and drought levels virtually impossible 20 years ago reach 1-in-10 likelihoods as early as the 2030s. By 2050–2074, two successive years of single or compound end-of-century extremes, unprecedented to date, exceed 1-in-10 likelihoods; while Europe-wide 5-year megadroughts become plausible. Whole decades of end-of-century heat stress could start by 2040, by 2020 for drought, and with a warm North Atlantic, end-of-century decades starting as early as 2030 become twice as likely.
Promising TMDC-like optical and excitonic properties of the TiBr2 2H monolayer
Authors: Batista André L. de O. , Palheta João Marcos T. , Piotrowski Maurício J. , Rêgo Celso R. C. , Guedes-Sobrinho Diego , Dias Alexandre C. 
Published: November 2023

Our simulation protocol allows exploring promising 2D materials for optoelectronic applications, like the TiBr2 2H monolayer, demonstrating TMDC-like optical and excitonic properties.
Statistical inversion of normal‐mode interference spectral parameter in ocean waveguide
Authors: Gao Wei , Zhu Shuping , Li Xiaolei 
Published: November 2023

AbstractA statistical inversion method of estimating normal mode interference spectral parameters (including waveguide invariance and interference frequency) from one‐dimensional broadband sound intensity spectrum (1D BSIS) is presented. First, the interference phase of 1D BSIS is compensated by a non‐linear factor for each pair of unknown parameters in a prior parameter space. Second, the singular value decomposition is performed for a data matrix, which is constructed by the phase‐compensated BSIS. Then, a misfit function is defined based on both the maximum singular value and the corresponding singular vector of the data matrix. Finally, the posterior probability distributions of unknown parameters are analysed based on statistical inversion theory. This method is suitable for the situation using a single receiver and without any environmental information. Numerical simulations illustrate the validity of the presented method.
Design and optimisation of oil injection pipe cooling structure for permanent magnet synchronous motors in hybrid electric vehicles
Authors: Xie Ying , Zhao Xiangmin , Cai Wei , Qi Guoliang , Wang Zebing , Zhang Yi , Yang Yanhui 
Published: November 2023

AbstractIn recent years, with the continuous improvement of motor power density, oil cooling technology has been widely used in permanent magnet synchronous motors (PMSMs) for electric vehicles (EVs) as an efficient cooling method. A PMSM with a rated capacity of 53kW for hybrid electric vehicles (HEVs) is designed, and the motor is cooled by the oil injection pipe. In order to improve the heat dissipation efficiency of the end winding, the number of injection pipes and the structure of the nozzle are optimised, and a novel nozzle structure is proposed. By using the moving particle solution (MPS) method to simulate the fluid flow, the optimal cooling structure of the motor is determined. In addition, different from the equivalent winding model in the traditional temperature field simulation, a hairpin winding model that can more realistically reflect the geometry of the end winding is established. On this basis, the temperature field of the motor is simulated. It is verified that the cooling structure designed can effectively improve the thermal performance of the end winding.
Optimal electric vehicle scheduling in unbalanced distribution system by spatial and temporal data mining and bi‐level particle swarm optimisation
Authors: Piamvilai Nattavit , Sirisumrannukul Somporn 
Published: November 2023

AbstractThis research proposes a new comprehensive methodology aimed at optimally managing electric vehicle (EV) charging in an unbalanced distribution system with consideration of grid capacity and voltage quality constraints as well as the stochastic driving and charging behaviour of EV users. A data mining algorithm is designed to generate suitable spatial and temporal EV and charger input data for EV scheduling that is decomposed into two subproblems. The lower‐level subproblem identifies the maximum load at each node and time and the upper‐level subproblem allocates charging slots for each EV being charged. Both subproblems are solved by developed particle swarm optimisation (PSO) algorithms. The effectiveness and robustness of the algorithms have been thoroughly validated by conducting rigorous tests on a modified IEEE 37‐bus distribution system with different EV penetration scenarios. The test results have confirmed the algorithms' performance in accommodating the increasing load associated with EV charging and successfully improving the system performance by maximising the system load factor, minimising load unbalance, and reducing the system power loss. All operational constraints on node voltages, and distribution transformer and feeder capacities of the existing power distribution infrastructure are fully respected while maintaining high user satisfaction represented by the average state of charge (SoC) of all EVs.
Induction of Labour with a Double Balloon Catheter – Comparison of Effectiveness of Six Versus Twelve Hours Insertion Time: a Prospective Case Control Study
Authors: Strößner Lena , Heimann Yvonne , Schleußner Ekkehard , Kolterer Anna 
Published: November 2023

AbstractInduction of labour is a common obstetric procedure to initiate or augment contractions when labour is delayed or uncertain. The double balloon catheter is a safe and effective mechanical
method for cervical ripening during induction of labour. This study evaluates the effectiveness of reducing double balloon catheter insertion time from 12 to 6 hours.248 women undergoing induction with a double balloon catheter at term were divided into two groups: catheter placed for 12 hours at 8 pm in the first half of 2021 (P12) and catheter placed
for 6 hours at 7 am in the second half of 2021 (P6). T-tests, chi-squared tests, and Wilcoxon signed rank test were used for statistical analysis. Primary and secondary endpoints included
induction to delivery interval, prostaglandin to delivery interval, mode of delivery, and maternal and neonatal outcomes.The P6 group had a significantly reduced induction to delivery interval of 558 min (P6: 1348 min, P12: 1906 min, p < 0.01, 95% CI: 376–710) within demographically comparable groups.
Multiparous women also showed a significant reduction in prostaglandin to delivery interval of 260 min (P6: 590 min, P12: 850 min, p = 0.038, 95% CI: 9–299). There were no significant
differences in mode of delivery, maternal blood loss, or neonatal outcome.Reducing double balloon catheter placement time from 12 to 6 hours resulted in almost 9 hours less induction to delivery interval without adverse effects on maternal and neonatal
outcome.
Dashboarding to Monitor Machine-Learning-Based Clinical Decision Support Interventions
Authors: Hekman Daniel J. , Barton Hanna J. , Maru Apoorva P. , Wills Graham , Cochran Amy L. , Fritsch Corey , Wiegmann Douglas A. , Liao Frank , Patterson Brian W. 
Published: November 2023

Abstract
Background Existing monitoring of machine-learning-based clinical decision support (ML-CDS) is focused predominantly on the ML outputs and accuracy thereof. Improving patient care requires not only accurate algorithms but also systems of care that enable the output of these algorithms to drive specific actions by care teams, necessitating expanding their monitoring.
Objectives In this case report, we describe the creation of a dashboard that allows the intervention development team and operational stakeholders to govern and identify potential issues that may require corrective action by bridging the monitoring gap between model outputs and patient outcomes.
Methods We used an iterative development process to build a dashboard to monitor the performance of our intervention in the broader context of the care system.
Results Our investigation of best practices elsewhere, iterative design, and expert consultation led us to anchor our dashboard on alluvial charts and control charts. Both the development process and the dashboard itself illuminated areas to improve the broader intervention.
Conclusion We propose that monitoring ML-CDS algorithms with regular dashboards that allow both a context-level view of the system and a drilled down view of specific components is a critical part of implementing these algorithms to ensure that these tools function appropriately within the broader care system.
Catalytically Competent Fluorinated Barnase Variants
Authors: Koksch Beate , Langhans Alexander , Krummhaar Michael , Roth Christian 
Published: November 2023

AbstractProteins play critical roles in all living organisms, and their properties and functions result directly from their primary sequences. Fluorine, though seldom found in natural organic compounds, has been shown to impart desirable properties to small molecules and proteins alike. However, studies on the impact of this element in enzyme activity and protein–protein interaction are largely absent from the literature. Here we present a microwave-assisted SPPS method for the total synthesis of site-specifically fluorinated barnase variants, as well as characterization of their folding and activity. CD spectroscopy and fluorescence-based activity assays show that the fluorinated amino acids are generally not perturbative of the protein structure and that enzyme activity, albeit reduced, is retained in all variants.
Clinical spectrum of myelin oligodendrocyte glycoprotein antibody-associated disease in Brazil: a single-center experience
Authors: Messias Katharina , Moreto Renata , Cruz Camila Aquino , Ronchi Nathalia Rossoni , Santos Antonio Carlos dos , Messias André , Marques Vanessa Daccach 
Published: November 2023

AbstractBackground Anti-myelin oligodendrocyte glycoprotein (anti-MOG) antibody-associated disease (MOGAD) is an immune-mediated neurological disorder with a broad spectrum of clinical presentation that is often difficult to distinguish from other demyelinating diseases, such as multiple sclerosis and neuromyelitis optica spectrum disorder.Objective To describe the clinical and paraclinical characteristics of MOGAD in a Brazilian tertiary center.Methods We retrospectively reviewed the records of adult and pediatric patients who tested positive for anti-MOG antibodies and presented with clinical and radiological diseases compatible with MOGAD.Results Forty-one patients (10 children) were included: 56% female, 58% Caucasian, mean age at onset 31 years (range 6-64), with a mean disease duration of 59.6 months (range 1-264 months). The most frequent onset presentation was optic neuritis (68%), acute disseminated encephalomyelitis (ADEM, 12%), and myelitis (10%). A monophasic disease course was observed in 49%. EDSS median was 2.1 at the last visit. Most patients (83%) were under continuous immunosuppressive treatment. Azathioprine was the first-line treatment in 59%. In all ADEM cases, conus, and root involvement was radiologically observed on MRI.Conclusion Brazilian MOGAD patients presented with a similar spectrum of previously reported MOGAD phenotypes. Conus and spinal root involvement seems to be frequently present in MOGAD-ADEM and could serve as radiologic characteristics of this clinical entity.
Family support in adults with epilepsy
Authors: Tedrus Gloria M. A. S. , Leandro-Merhi Vania Aparecida , Etchegaray Augusto , Randi Yara Maria 
Published: November 2023

Abstract
Background The perception of family support in chronic disease can be relevant.
Objective To assess the perception of family support in adult patients with epilepsy (PWEs) and relate it to quality of life (QoL) and clinical aspects.
Methods Data from the Perceived Family Support Inventory (IPFS) of 130 PWEs were related to the clinical variables, QOLIE-31 scores, and the Neurological Disorders Depression Inventory for Epilepsy (NDDI-E) with statistical tests, with p < 0.05.
Results The mean age was 49.9 ± 17.2 years, and the duration of epilepsy was 20.8 ± 15.4 years. The presence of depression (scores ≥ 15) was associated with lower family support. Being married and non-occurrence of depression were the variables associated with a higher IPFS score (R = 0.2112), in the multiple linear regression.
Conclusion The perception of greater family support was associated with demographic aspects, the absence of depression, and better QoL. Family relationships may play an essential role in health adjustment behaviors and QoL in epilepsy.
Quality of life in Down syndrome in Brazil: a cross-sectional study
Authors: Bermudez Beatriz Elizabeth Bagatin Veleda , Franklin Gustavo Leite , Oliveira Camila Maciel de , Coutinho Léo , Crippa Ana Chrystina de Souza 
Published: November 2023

Abstract
Background Down syndrome is the most commonly genetic cause of developmental delay and intellectual disability, affecting 1:700 live births. It is associated with heart disease and recurrent infections, among other complications that greatly impair the patient's quality of life.
Objective To evaluate the major factors associated with quality of life in a cohort of patients with Down syndrome.
Methods We assessed 1,187 patients with Down syndrome, older than 4 years old, with an adaptation of the Personal Outcomes Scale validated for Portuguese language, interviewing patients, parents, and caregivers.
Results A bad quality of life was reported in 56.4% of the sample. The main factors associated with better quality of life were female sex, first medical visit before 4 months old, higher parental education, a professionally active mother, and prenatal care. The main factors associated with worse quality of life were family history of alcohol abuse and psychiatric disorders and comorbidity with autism and epilepsy.
Conclusion Clinical comorbidities such as autism and epilepsy carry a heavy burden among patients with Down syndrome, while factors related to family support, such as employment status and educational background of the parents, enhance quality of life. The factors associated with quality of life among patients with Down syndrome should be adequately evaluated in medical consultation and targeted in public health policies.
Acousto-optic stimuli to promote coherent 40-Hz frequency entrainment effect
Authors: Han Xue , Wang Lei , Yang Shuo 
Published: November 2023

Abstract
Background Research has shown that a fundamental frequency of 40 Hz in continuous neural oscillation is indicative of normal brain activity; in Alzheimer disease (AD) patients, these oscillations either disappear or are significantly interrupted. Research has also indicated that the degenerative impacts of AD in mice were mitigated by the synchronization of 40-Hz acousto-optic stimulation (AOS).
Objective To examine the impact of employing a 40-Hz AOS intervention on the induction of a substantial 40-Hz frequency entrainment and improvement in working memory performance among a sample of young individuals in good health. We conduct an analysis of event-related potentials (ERPs) derived from electroencephalogram (EEG) data following the presentation of AOS.
Methods We recruited 20 healthy volunteers (median age: 25 years; 8 female subjects). Following the administration of various stimuli, including no stimuli, 40-Hz AOS, pink noise, and 40Hz acoustic stimuli (AS), the participants were required to complete a working memory task. A total of 62 electrodes were used to record EEG data, which was subsequently analyzed to investigate the impact of AOS on the activity of working memory. We also aimed to determine if AOS lead to a more pronounced 40-Hz frequency entrainment.
Results Following the administration of AOS, a notable enhancement in the 40-Hz power of pertinent cerebral areas was observed, accompanied by a substantial improvement in the performance of the subjects on working memory tests subsequent to the stimulation.
Conclusion The findings unequivocally establish the efficacy of using AOS to enhance the 40-Hz power and working memory.
Volar Plate-Suture Fixation in the Treatment of Volar Rim Fractures of the Distal Radius
Authors: Carney John , Bigach Stephen , Goedderz Cody , Gerlach Erik , Marx Jeremy , Kalainov David 
Published: November 2023

Abstract
Background The purpose of this study was to describe the volar plate-suture fixation technique for augmented repair of volar rim fractures of the distal radius and to report clinical outcomes and radiographic findings.
Materials and Methods Twenty-one patients treated with volar plate-suture fixation were retrospectively reviewed. Outcomes of interest included pain, joint motion, grip strength, surgical complications, additional surgeries, and radiographic parameters.
Results Final follow-up office visits from surgery averaged 30.8 weeks (range 6–175 weeks). There was no report of residual wrist pain in most cases. Forearm and wrist motion measurements were within functional ranges and grip strength measurements averaged 63 ± 21% of the contralateral hand. There were no cases of infection, wound dehiscence, nerve injury, or nonunion. Hardware removal was performed in four patients for wrist pain attributed to the fixation implant(s). One patient underwent a wrist fusion for treatment of painful traumatic wrist arthritis. Failure of the fracture fixation construct to hold the carpus occurred in two patients. Changes in radiocarpal and intercarpal angles averaged less than 4 degrees and loss of articular reduction averaged less than 1 mm, although with relatively high standard deviations.
Conclusion Suture fixation of volar rim fractures of the distal radius may be a useful technique in augmenting volar plate fracture fixation. Some loss of early postoperative fracture alignment should be expected.
Level of Evidence IV, case series.
Polarising metaphors in the Venezuelan Presidential Crisis
Authors: Peterssen Silvia , Soares da Silva Augusto 
Published: November 2023

Abstract
The 23rd of January 2019 marked the beginning of the Venezuelan Presidential Crisis, a unique socio-political
conflict that confronted Nicolás Maduro, president of Venezuela, to the self-proclaimed leader Juan Guaidó. This paper explores
the divisive power of conceptual metaphors in this context through the analysis of polarising metaphors, namely, metaphors that
conceptualise ‘Us’ positively and/or ‘Them’ negatively. More specifically, from a corpus-based critical socio-cognitive
perspective (Musolff 2016; Soares da Silva
2020; Charteris-Black 2011), this study looks at the main polarising
metaphors of Maduro and Guaidó’s political discourses and examines their role in the discursive construction of ideological
polarisation, social identities, and legitimacy using a target-based approach (Stefanowitsch
and Gries 2006). The results show that both leaders strategically use polarising metaphors, especially those of
CONFRONTATION, HUMAN BEING and JOURNEY, to reproduce their ideologies, reinforce their social
identities, and legitimise their political positions.
Effect of the focusing system on measurements in gravitational wave detection telescope
Authors: Fan Wentong , Fang Sijun , Hai Hongwen , Song Jie , Zhao Kai , Zhang Rui , Li Bohong , Luo Jian , Fan Lei , Li Zizheng , Zhao Hongchao , Yan Yong 
Published: November 2023

Abstract
Telescopes primarily transmit and receive laser beams over long distances as part of a gravitational wave interferometric measurement system. Due to factors such as optical design, fabrication, and alignment, the wavefront at the exit pupil of the telescope inevitably experiences distortion, resulting in wavefront aberrations that couple with pointing jitter to generate tilt-to-length (TTL) coupling noise. During the process of gravitational wave detection, the large distance between the primary and secondary mirrors and temperature fluctuations in space can cause significant axial misalignment between them. This results in a substantial displacement of the primary-secondary mirror system’s primary focus along the axial direction, further degrading the wavefront at the exit pupil of the telescope. The TTL coupling noise caused in this scenario will affect the detection of gravitational waves, thus requiring the adjustment of the position of the three-four mirror system through the focusing system to minimize TTL coupling noise. In this paper, the model for TTL coupling noise was established using the first 36 orders of Zernike polynomials. The misalignment model of the primary-secondary mirror system was derived using geometric optics theory. The study investigates the influence of the telescope focusing system before and after focusing on the wavefront aberrations and TTL coupling noise at the exit pupil of the telescope. The analysis indicates that with a misalignment of 7.56 μm in the axial distance between the primary and secondary mirrors, the addition of a focusing system reduces the wavefront error at the exit pupil of the telescope from 0.0328 λ to 0.0046 λ. Furthermore, the maximum coupling noise between wavefront distortion and pointing jitter is reduced from 4 pm Hz−1/2 to 0.4 pm Hz−1/2. This provides valuable insights for the design of gravitational wave detection telescopes and the study of focusing systems.
Photocatalytic water splitting properties of GeC/InS van der Waals heterostructure: first-principles calculations
Authors: Wang Jiaxin , Liang Kanghao , Wei Xing , Zhang Yan , Chen Huaxin , Yang Yun , Liu Jian , Tian Ye , Duan Li 
Published: November 2023

Abstract
Based on first-principles, we conducted an in-depth study of the GeC/InS van der Waals heterostructure formed by GeC and InS and discussed its structure, electronic properties and optical properties. First, we observe that this heterostructure has negative binding energy, indicating that the interlayer interactions are mainly affected by van der Waals forces. Through band structure and density of state analysis, we confirmed its type-II band alignment characteristics, which means that photogenerated carriers have the ability to automatically separate in space. Moreover, the average charge density difference and Bader charge analysis show that there is a built-in electric field in the heterostructure, and further proves that GeC/InS forms a Z-scheme charge transfer mechanism. Interestingly, the band edge position spans the water redox potential and can fully induce the redox reaction of water splitting, indicating that it is a potential photocatalyst. The high light absorption coefficient shown in the absorption spectrum also further confirms its excellent photocatalytic activity. The most striking thing is that the solar hydrogen production efficiency of GeC/InS heterostructure is as high as 44.39%. Our research demonstrates the theoretical basis for GeC/InS heterostructure as a photocatalyst.