bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gel shrinking resulting from uneven distribution of ionic micelles between the inside and the outside of the polymer gel network
Authors: El Sayed A. Mounir , Kawasaki H. , Maeda H. 
Published: June 2004

AbstractThe volume change of crosslinked nonionic poly (N‐isopropylacrylamide) (NIPA) polymer gel immersed in tetradecyldimethylaminoxide (C14DMAO) surfactant solutions at 0.1M NaCl, were investigated to distinguish between binding and nonbinding polymer gel/C14DMAO surfactants. Also, the aggregation behavior of C14DMAO surfactants the inside and the outside the polymer hydrogels has been studied through solubilization of Sudan III dye. For the C14DMAO surfactants at the degrees of ionization (α) of 0.5 and 1, they bind to the NIPA gel at low surfactant concentration (CD) that enhance the gel swelling due mainly to the osmotic pressure contribution from the counter ions (regime I, CD<10mM). However, the deswelling behavior was observed as the surfactant concentration increases above 10 mM (regime II). The solubilization experiments indicated that the surfactant concentration inside the gel is lower than that outside the gel in the regime II, which may be due to the large micelle size that cannot accommodate the mesh size of the gel. It was suggested that the uneven distribution of the ionic micelles leads to the reduction of the net swelling osmotic pressure of the gel (i.e., the decrease of the gel volume). In the case of the nonionic C14DMAO at α = 0, on the other hand, the deswelling behavior was not clearly observed and the surfactant concentration inside the gel and outside the gel was almost identical even at 30 mM. For the nonionic surfactant, it was also found that the gel volume increases with the surfactant concentration at low surfactant concentration less than 1mM. This may be attribute to the dipole‐dipole repulsion of N‐O headgroups. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 93: 2001–2006, 2004
Kinetic study of radical polymerization. III. Solution polymerization of acrylamide by 1H‐NMR
Authors: Mahdavian Ali‐Reza , Abdollahi Mahdi , Bijanzadeh Hamid Reza 
Published: June 2004

AbstractSolution and radical polymerization of acrylamide in the presence of potassium persulfate in D2O was investigated up to high conversion by high‐field 1H‐NMR spectroscopy. The kinetics of reaction was studied according to the data obtained from the corresponding spectra at various times during the polymerization reaction progress. Processing of the data led us to derive the rate equation of this polymerization reaction and determine the reaction order of each component in the rate equation. The order, with respect to initiator, was consistent with the classical kinetic rate equation (0.45), whereas the order with respect to monomer was greater than unity (1.49). The effect of temperature on the polymerization rate was also investigated and the activation energy of 48.4 kJ mol−1 was obtained over the temperature range of 60–75°C. Also some mechanistic studies were discussed. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 93: 2007–2013, 2004
Surface modification of polyethylene by plasma pretreatment and UV‐induced graft polymerization for improvement of antithrombogenicity
Authors: Chen Yashao , Liu Peng 
Published: June 2004

AbstractThe purpose of this study was to enhance blood compatibility of polyethylene (PE) films. Glycidyl methacrylate (GMA) was grafted onto the surface of PE by Ar plasma pretreatment and UV‐induced graft polymerization without photo‐initiator, then heparin was immobilized onto the poly (glycidyl methacrylate) segments. The surface compositions and microstructure of GMA graft polymerized PE films were studied by X‐ray photoelectron spectroscopy (XPS) and Attenuated Total Reflectance Fourier Transfer Infrared (ATR‐FTIR) spectroscopy. It was confirmed that heparin was successfully immobilized onto the surface of PE films by XPS analysis. The antithrombogenicity of the samples was determined by the activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT), and plasma recalcification time (PRT) tests and platelet adhesion experiment. Results indicated that the antithrombogenicity of modified PE was improved remarkably. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 93: 2014–2018, 2004
Peak‐fitting analysis of cotton fiber powder X‐ray diffraction spectra
Authors: Chen Runying , Jakes Kathryn A. , Foreman Dennis W. 
Published: June 2004

AbstractThe precision and accuracy of diffraction peak positions resolved from the powder X‐ray diffraction spectra of cotton fibers by means of the residuals peak‐fitting procedure of a commercial peak‐fitting software package (PeakFit®) was investigated to explore the potential of such programs in providing reliable data that are not readily apparent in diffuse X‐ray spectra. Each intensity spectrum was fitted by employing a Gaussian function as the peak profile. The precision of 15 pairs of the resolved diffraction peaks is 0.0017 mm; 9 of the 15 pairs fall into the 99% confidence interval. The precision in 2θ of four commonly identified peaks through four independent fittings is from 0.002 to 0.014°. The 2θ accuracy of the resolved peaks is good in comparison to data calculated for both the traditionally accepted and the more recently revised concepts of the cellulose I crystal structure. A peak resolved at about 15.3° may be attributed to the triclinic crystal structure component of cellulose I. Although distinct peaks are not readily apparent in the diffuse spectrum of cellulose, peak‐fitting procedures may provide additional data for structure determination. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 93: 2019–2024, 2004
Crystal structures of collagen model peptides with Pro‐Hyp‐Gly repeating sequence at 1.26 Å resolution: Implications for proline ring puckering
Authors: Okuyama Kenji , Hongo Chizuru , Fukushima Rie , Wu Guanghan , Narita Hirotaka , Noguchi Keiichi , Tanaka Yuji , Nishino Norikazu 
Published: June 2004

AbstractTriple‐helical structures of (Pro‐Hyp‐Gly)n (n = 10, 11) at 100 K and room temperature (RT) were analyzed at 1.26 Å resolution by using synchrotron radiation data. Totals of 49 and 42 water molecules per seven triplets in an asymmetric unit were found for the structures at 100 K and RT, respectively. These water molecules were classified into two groups, those in the first and second hydration shells. Although there was no significant difference between water molecules in the first shell at 100 K and those at RT, a significant difference between those in the second shell was observed. That is, the number of water molecules at RT decreased to one half and the average distance from peptide chains at RT became longer by about 0.3 Å. On the other hand, of seven triplets in an asymmetric unit, three proline residues at the X position at 100 K clearly showed an up‐puckering conformation, as opposed to the recent propensity‐based hypothesis for the stabilization and destabilization of triple‐helical structures by proline hydroxylation. This puckering was attributed to the interaction between proline rings and the surrounding water molecules at 100 K, which is much weaker at RT, as shown by longer average distance from peptide chains. © 2004 Wiley Periodicals, Inc. Biopolymers (Pept Sci), 2004
Clopidogrel‐associated autoimmune thrombocytopenic purpura
Authors: Best Patricia J.M. , Mathew Verghese , Markovic Svetomir N. 
Published: June 2004

AbstractWe report the case of a 51‐year‐old male who underwent coronary stent placement for the treatment of an acute myocardial infarction. One week later, he developed symptomatic autoimmune thrombocytopenia likely related to clopidogrel use. This was successfully treated with intravenous methylprednisilone and platelet transfusions. Catheter Cardiovasc Interv 2004;62:339–340. © 2004 Wiley‐Liss, Inc.
Favorable effect of γ‐radiation for in‐stent restenosis: Effect of diabetes on angiographic and clinical outcomes
Authors: Iakovou Ioannis , Mehran Roxana , Dangas George , Lansky Alexandra J. , Stone Gregg W. , Mintz Gary S. , Aymong Eve , Ashby Dale T. , Pichard Augusto D. , Satler Lowell F. , Kent Kenneth , Leon Martin B. , Waksman Ron 
Published: June 2004

AbstractThe purpose of this study was to examine the effect of vascular brachytherapy with γ‐radiation (γ‐RT) in patients with diabetes mellitus (DM) with coronary in‐stent restenosis (ISR). In the Washington Radiation for In‐Stent Restenosis (WRIST) trial, 130 patients with ISR were treated with 192Ir or placebo. Of the patients enrolled, 44 (34%) had DM (18 of them treated with γ‐RT and 26 with placebo). γ‐radiation therapy of ISR in diabetics resulted in similar procedural success and in‐hospital outcome compared to nondiabetics. At 6‐month follow‐up, both DM and non‐DM patients treated with γ‐RT had significantly lower target lesion revascularization (TLR), target vessel revascularization, and major adverse cardiac event rates compared to placebo. DM remains a powerful predictor of TLR and major adverse cardiac events even after treatment of ISR with γ‐RT. Catheter Cardiovasc Interv 2004;62:303–307. © 2004 Wiley‐Liss, Inc.
New echocardiographic diameter for Amplatzer sizing in adult patients with secundum atrial septal defect: Preliminary results
Authors: Carcagnì Addolorata , Presbitero Patrizia 
Published: June 2004

AbstractAnatomical atrial septal defect (ASD) diameter measured by transesophageal echocardiography (TEE) underestimates the Amplatzer septal occluder (ASO) size for ASD closure. The aim of this study is to investigate whether a new echocardiographic diameter (procedural ASD diameter) may enable precise measurements of ASO device size. Fifty adult patients with secundum ASD were evaluated by TEE for percutaneous closure. The procedural ASD diameter was measured using the steadier rim borders where thickness was 2.5 mm. Out of the 50 patients, 12 were considered unsuitable for Amplatzer device closure. The other 38 patients underwent percutaneous closure. The mean anatomical ASD diameter was 14.8 ± 7.0 mm, the mean procedural ASD diameter measured 19.5 ± 8.1 mm, and the mean stretched balloon diameter (SBD) was 20.0 ± 8.0 mm. ASO device size was 20.1 ± 8.0 mm. At linear regression analysis, a high correlation (r = 0.99) was found between procedural ASD diameter and SBD. Procedural ASD diameter correlates with SBD and may allow reliable prediction of Amplatzer device in an adult population undergoing percutaneous ASD closure. Catheter Cardiovasc Interv 2004;62:409–414. © 2004 Wiley‐Liss, Inc.
Rescue angioplasty after failed intra‐arterial thrombolysis in acute middle cerebral artery stroke: A case report
Authors: Agarwal Pinky , Borden Neil , Tan Walter A. , Sen Souvik 
Published: June 2004

AbstractIntra‐arterial thrombolysis is increasingly being used in the treatment of acute ischemic stroke with a failure rate of recanalization as high as 66%. We describe a case of acute ischemic stroke secondary to occlusion of the middle cerebral artery that failed intra‐arterial thrombolytic therapy but responded to rescue balloon angioplasty. Catheter Cardiovasc Interv 2004;62:396–400. © 2004 Wiley‐Liss, Inc.
Deep vein thrombosis in the arm following transradial cardiac catheterization: An unusual complication related to hemostatic technique
Authors: Hall Ian R. , Lo Ted S.N. , Nolan James 
Published: June 2004

AbstractTransradial cardiac catheterization is an increasingly popular technique mainly because of the low vascular complication rate. We report a case of arm deep vein thrombosis that may be related to a common puncture site hemostasis technique. This complication supports the use of specific unilateral compression hemostatic systems following transradial procedures. Catheter Cardiovasc Interv 2004;62:346–348. © 2004 Wiley‐Liss, Inc.
Percutaneous treatment of left main coronary stenosis as a late complication of bentall operation for acute aortic dissection
Authors: Balbi Manrico , Olivotti Luca , Scarano Flavio , Bertero Giovanni , Passerone Giancarlo , Brunelli Claudio , Barsotti Antonio 
Published: June 2004

AbstractSevere ostial left main coronary stenosis developed 35 days after successful Bentall‐type operation for acute aortic dissection. Treatment of this kind of complication is usually performed with open chest coronary artery bypass grafting. In our case, treatment with percutaneous transluminal coronary angioplasty and stenting of the lesion immediately after diagnostic coronary angiography was performed successfully, with persisting good results at 9‐month clinical follow‐up. Catheter Cardiovasc Interv 2004;62:343–345. © 2004 Wiley‐Liss, Inc.
γ δ T cells inhibit in vitro growth of the asexual blood stages of Plasmodium falciparum by a granule exocytosis‐dependent cytotoxic pathway that requires granulysin
Authors: Farouk Salah E. , Mincheva‐Nilsson Lucia , Krensky Alan M. , Dieli Francesco , Troye‐Blomberg Marita 
Published: June 2004

AbstractSeveral reports have stated the ability of γ δ T cells to inhibit the growth of the asexual blood stages of Plasmodium falciparum in vitro. However, little information is available about the mechanisms involved. In this study, in vitro systems were used to study the role of the granule exocytosis‐dependent cytotoxic pathway in the growth inhibition/killing of P. falciparum by human γ δ T cells. Our results show that the inhibition requires cell‐to‐cell contact and that γ δ T cells kill the asexual blood stages of P. falciparum through a granule exocytosis‐dependent cytotoxic pathway after recognition of certain ligands or molecules expressed on the surface of infected erythrocytes or merozoites. The in vitro inhibitory capacity of γ δ T cells was strongly correlated with the expression of granulysin in the cytotoxic granules, while non‐inhibitory CD4+ and CD8+ T cells expressed very little, implicating a role for granulysin in parasite inhibition. This was further suggested by the addition of neutralizing anti‐granulysin antibodies, which abrogated the parasite inhibitory capacity of the γ δ T cells. Taken together, our results suggest that the capacity of γ δ T cells for inhibition/killing of P. falciparum is based on the granule exocytosis‐dependent cytotoxic pathway and that the presence of granulysin is essential to maintain efficient killing.
Electron‐Rich Organoantimony(III) Dithiolate Complexes
Authors: Avarvari Narcis , Fourmigué Marc , Canadell Enric 
Published: June 2004

AbstractElectron‐rich dithiolene complexes of the antimony(III) PhSb moiety, formulated as [SbPh(dddt)] (1) (dddt: 5,6‐dihydro‐1,4‐ditthine‐2,3‐dithiolate) and [SbPh(EDT‐TTFS2)] (2) (EDT‐TTFS2: 4,5‐ethylenedithio‐tetrathiafulvalene‐4′,5′‐dithiolate), have been prepared by deprotection of the corresponding precursors and trapping of the intermediate dithiolates with PhSbCl2. Both complexes have been structurally characterized. The analysis of their single‐crystal X‐ray structures shows original supramolecular organizations governed by secondary Sb···S contacts, with distorted octahedral coordination geometries around the Sb center. Band‐structure calculations for complex 2 reveal only weak dispersion of the valence and conduction bands, with an energy gap of 1.68 eV. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Bonding, Metal‐Atom Dynamics and Hyperfine Interactions of η‐Phospholyl‐ and η‐Pentaphospholyliron Complexes
Authors: Herber Rolfe H. , Nowik Israel , Loginov Dmitry A. , Starikova Zoya A. , Kudinov Alexander R. 
Published: June 2004

AbstractA number of structurally related sandwich compounds of iron, in which the central metal atom is ligated to rings containing one or five phosphorus atoms, have been investigated by temperature‐dependent 57Fe Mössbauer spectroscopy, differential scanning calorimetry and single‐crystal X‐ray diffraction. The quadrupole hyperfine interaction at 90 K evidences a linear dependence on the number of ring phosphorus atoms, decreasing by about 0.35 mm·s−1 for each ring carbon atom replaced by P. This effect is directly related to the change in the overlap between metal atom d‐orbitals and ligand 3s,3p or 2s,2p orbitals due to an increase in the respective bond lengths. Several one‐electron oxidation products of these compounds, which are paramagnetic, have also been examined and show spin−lattice relaxation rates which are fast compared to the characteristic Mössbauer timescale of 98 ns at all temperatures above 90 K. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Prevalence of personality disorders in patients with eating disorders: a pilot study using the IPDE
Authors: Marañon Izaskun , Echeburúa Enrique , Grijalvo Jorge 
Published: June 2004

AbstractObjectiveThe present study aims to determine the comorbidity of personality disorders (PD) with anorexia and bulimia nervosa, and to establish the major personality characteristics of eating disorders subtypes.MethodUsing the International Personality Disorders Examination (IPDE), the study investigated the personality profiles of 66 outpatients with eating disorders. Statistical analyses were carried out using non‐parametric methods such as the Kruskal‐Wallis H test and Mann‐Whitney U.Results51.5% of the overall sample met criteria for at least one personality disorder. Purging anorexia nervosa patients were the most affected. The most common personality disorders were obsessive‐compulsive, avoidant, dependent, borderline and not otherwise specified.DiscussionMore than half of the subjects with AN and BN met the criteria for at least one PD. This finding is a challenge for clinical practice. Implications for further research in this area are commented on. Copyright © 2004 John Wiley & Sons, Ltd and Eating Disorders Association.
Eating disorders and general psychopathology: a comparison between young adult patients and normal controls with and without self‐reported eating problems
Authors: Ekeroth K. , Broberg A. G. , Nevonen L. 
Published: June 2004

AbstractAimTo investigate general psychopathology among women with DSM‐IV confirmed eating disorders (ED) and women from the general population with and without self‐reported eating disorder problems.MethodNinety‐six ED patients between 18 and 26 years (M = 21.59, SD = 2.01) were compared with 265 randomly chosen age‐matched controls (M = 20.99, SD = 2.01) with the Symptom Check List‐90 (SCL‐90).ResultED patients scored significantly higher on all subscales compared with women without self‐reported eating problems, and higher on several scales compared to women reporting previous eating problems. There were no differences between ED patients and controls with current eating problems. Women with self‐reported eating disorder problems scored significantly higher than women without such problems on all scales except for ‘phobic anxiety’.DiscussionIncreased psychopathology in both ED patients and women with self‐reported eating problems suggests that general psychopathology is related to eating disturbances per se, and not only to being a psychiatric patient. Copyright © 2004 John Wiley & Sons, Ltd and Eating Disorders Association.
High‐resolution image cytometry on smears of normal oral mucosa: a possible approach for the early detection of laryngopharyngeal cancers
Authors: Neher Andreas , Öfner Günter , Appenroth Elisabeth , Gschwendtner Andreas 
Published: June 2004

AbstractBackground.The purpose of this study was to investigate the possibility of identifying laryngopharyngeal cancers by nuclear chromatin texture feature analysis of cell nuclei from mucosal scrapings obtained from clinically and cytologically noncancerous areas of the soft palate in patients with cancer.Methods.The collective consisted of 68 controls and 77 cases of laryngopharyngeal carcinomas. After Feulgen staining, 3000 cell nuclei were automatically measured using a high‐resolution image analyser (CytoSavant Oncometrics, Vancouver, BC, Canada). Texture features were extracted for calculation of a discriminant function, which allows the two groups to be distinguished.Results.Two parameters allowed the two populations to be distinguished. The classifier reached an overall performance of 72.7% sensitivity, 82.4% specificity, a positive predictive value of 80.5%, a negative predictive value of 75.1%, and an area under the receiver operating characteristics (ROC) curve of 0.7754.Conclusion.Our work shows that subtle changes in the chromatin distribution in cell nuclei from ostensibly normal cells in the vicinity of carcinomas are demonstrable in the oral cavity of patients suffering from laryngopharyngeal cancers. It may be possible to develop this method into a valuable clinical tool to reduce the high rate of delayed diagnosis of oral and laryngopharyngeal cancers. © 2004 Wiley Periodicals, Inc. Head Neck 26: 694–700, 2004
Tumor apoptosis induced by ruthenium(II)‐ketoconazole is enhanced in nonsusceptible carcinoma by monoclonal antibody to EGF receptor
Authors: Strasberg Rieber Mary , Anzellotti Atilio , Sánchez‐Delgado Roberto A. , Rieber Manuel 
Published: June 2004

AbstractKetoconazole (KTZ) has been used as a second‐line agent in hormone‐refractory cancer therapy. Since transition metal complexes including those of Ru(III), show important anticancer activity with limited toxicity, we investigated the potential antitumor efficacy of Ru(II) complexed to KTZ or clotrimazole (CTZ) compared to Ru(II) alone or uncomplexed azoles. RuCl2(KTZ)2 exerted greater apoptosis‐ associated caspase‐3 activation than RuCl2(CTZ)2, KTZ, CTZ or RuCl2(MeCN)4 against several human tumor cell monolayers. PARP cleavage and a decrease in S+G2 cells were evident after RuCl2(KTZ)2 treatment in genetically matched C8161 melanoma monolayers with unequal p53 functional status. Release of mitochondrial cytochrome c and Mn‐SOD suggest mitochondria as a target of RuCl2(KTZ)2. Treatment of WM164 melanoma monolayers with 25 μM of cisplatin or RuCl2(KTZ)2 showed that the latter is more effective than cisplatin at inducing PARP fragmentation and proapoptotic Bak expression. Such results suggest that these Ru(II) and Pt(II) metal complexes are unequally effective and act through alternative signaling pathways. In studies with multicellular spheroids, which frequently are more resistant to cytotoxic anticancer drugs than monolayers, those from wt p53 C8161 melanoma underwent PARP fragmentation in response to RuCl2(KTZ)2. In contrast, spheroids of mut p53 A431 carcinoma overexpressing EGF receptor were resistant to either RuCl2(KTZ)2 or anti‐EGF receptor C225 MAb. However, joint treatment with both agents restored growth arrest and apoptosis in these spheroids. In contrast to the antitumor action of cisplatin, which is known to be hampered by p53 dysfunction, we show that RuCl2(KTZ)2 is active irrespective of p53 functional status against several adherent tumor cells and synergizes with anti‐EGF receptor C225 MAb to kill tumor spheroids resistant to either agent. © 2004 Wiley‐Liss, Inc.