bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge mapping of cell therapy in rheumatoid arthritis disease: a bibliometric analysis (2003-2023)
Authors: He Xiaoyao , Mi Liangyu , Ji Yuli , Zhao Miaomiao , Hu Yuting , Gao Yanan , Qiu Lixia , Xu Ke 
Published: December 2023

Abstract
Background:
Rheumatoid arthritis (RA) is a chronic autoimmune joint disease characterized by persistent synovitis and systemic inflammation of the joints. Cell therapy, a cellular drug delivery therapy based on the control of immune dysregulation, inflammatory cytokine production, and overall systemic inflammation, is expected to reverse the process of joint destruction when applied to RA. Based on this, the field of cell therapy applied to RA treatment has been gaining attention in recent years and many results have been achieved. Bibliometric analysis can provide insight into the development of a field. This study aims to provide an overview of the knowledge structure and research hotspots of cell therapy in RA through bibliometrics.
Method:
The Web of Science Core Collection (WoSCC) database was used to search the literature on cellular therapies related to RA between 2003 and 2023. VOSviewers, CiteSpace, and the R package "bibliometrics" were used to perform the bibliometric analysis.
Results:
This article includes 9341 articles from 107 countries, mainly from China and the United States. Fluctuating growth in the number of articles published on cell therapy applied to RA. The University of Amsterdam, Harvard University, Karolinska Institutet, and Stanford University are the main research institutions. The journal Arthritis Research & Therapy is the most popular journal in the field, and the journal Annals of Rheumatic Diseases is the most frequently cited. 44914 authors have published in this field, including more collaborative publications; Tak and Emery have published several papers, while Arnett Fc is the author of most frequently cited paper. The University of Amsterdam has been extensively involved in the publication of papers on this topic. France scientists have published fewer relevant papers as corresponding authors, but have been extensively involved in the investigation of this topic. The thematic analysis identified five research themes. The themes relate to monoclonal antibody therapy, tumour necrosis factor-alpha inhibitor therapy, gene and mesenchymal stem cell therapy, targeted immune cell and cytokine therapy, conventional therapy and novel therapy.
Conclusion:
This article is the first bibliometric study that comprehensively summarizes the research trends and their developments in the application of cell therapy to the treatment of RA. The content includes recent research results and hot directions in the field, providing reference information for scholars studying cell therapy and RA.
Accepting and Committing to Caregiving for Schizophrenia—A Mixed Method Pilot Study
Authors: Chakraborty Aishwarjya , Mitra Somdeb , Ray Deepshikha 
Published: December 2023

Abstract

Background. End of traditional institutionalized psychiatric care, diagnostic complexities, and associated stigma often negatively impact the social networks of caregivers, making them experience social isolation. Not the “identified patients”, caregiver perspectives are typically overlooked further adding to anticipatory stigma resulting in social death among them. Caregiving experience results in developing coping skills preventing carers from responding to the nuances of the context, and identifying the useful rules— "Experiential Avoidance”. Psycho-education is typically combined with other formal treatment programs for case conceptualization, and to provide a clear rationale for the treatment approach but less as a distinct psychotherapy. Borrowing the philosophy of Functional Contextualism, the present study developed a "Present-Moment Awareness" guided psychoeducational intervention. The aim was to reduce schizophrenia caregiver burden and anticipatory stigma and promote the value of caregiver participation as ‘experts by experience’.
Method. Five family caregivers of remitted schizophrenia patients were recruited using purposive sampling. Pre-post measure was taken on caregiver burden, caregiving experience, sense of personal mastery, and caregiving competence. Results were analysed quantitatively and qualitatively.
Results. A significant decrease in caregiver burden, stigma, and negative effects on the family in post-intervention was observed. Self-compassion led to a rise in a sense of empowerment.
Conclusion. Mainstreaming caregiver-centred “Present-Moment Awareness” guided psychoeducation is essential to address perceived stigma. Caregiver voices must be promoted to prevent social death of carers.
Research on Geometric Scheme for Shielding ADS Spallation Target
Authors: Deng Tianyu , Shen Xiukang , Cai Xiangming , Shan Jian 
Published: December 2023

Abstract
The ADS spallation target within the Accelerator-driven Subcritical System (ADS) serves as an external neutron source facilitating the transmutation process within the subcritical reactor. Upon protons from accelerators bombard the target, an extensive array of radioactive fragmentation products will be generate. Consequently, comprehensive investigation into the geometric configuration of the ADS target proves imperative, as it profoundly influences the distribution of radiation dosage. This study employed the Monte Carlo N-Particle (MCNP) program to simulate the radiation dose distribution of five targets, cuboid, hexagonal prism, cylindrical, spherical, and cube configurations, utilizing water as the shielding medium. We also optimized design of the shielding box which enables optimal conservation of shielding materials. Findings indicate: (1) When opting for a shielding geometric scheme for targets (or other body radiation sources), the spherical target is recommended. Up to 6.27% reduction in total dose compared to the other targets. (2) The shielding boxes for spherical and cube targets can be expanded in accordance with target proportions. The other shielding boxes can be tailored to the target shape. The present study holds instructive implications for post-processing investigations into the presently prevalent liquid lead-bismuth target. Additionally, research into the dose distribution of body source holds reference significance for selecting specific radiation fields.
Analysis of the effect of flow channel structure on centrifugal accelerated motion of particles in vacuum state
Authors: Sun Bo , Wei Shizhong , Li Peng , Guo Han 
Published: December 2023

Abstract
This study explores the impact of flow channel structure on the acceleration of metal particles in a vacuum environment, aiming to enhance acceleration quality in centrifugal impact molding of metal powders. To assess this, three evaluation indices are introduced: the average speed of particles thrown 𝑉𝑝, the average speed of the particles 𝑉𝑎𝑙𝑙, and the particle velocity distribution 𝑉𝑓(t). The research analyzes how six distinct runner structures influence the centrifugal acceleration of particles. Findings indicate that the arc-shaped flow channel structure not only ensures a more consistent acceleration process but also results in a higher ejection speed, leading to an improved acceleration effect. This study's unique contribution is its examination of the relationship between flow channel design and particle acceleration in a vacuum.
Enhanced Biomimetic Sensor for Cigarette Brand Differentiation using CdSe Quantum Dots and Machine Learning
Authors: Khan Arsala Zamir , Sharma Shalini , Ansari Tauseef Ahmad , Khan Prof. Dr.Shahbaz , Hussain Sayyed Aamir , Islam Shaziya , Telang Deepa , Mohd Abdul Ghaffar Noor , Shelke Sudhir , Harle Shrikant M. 
Published: December 2023

Abstract
In our doctoral research, we ex- plored the combined influence of CdSe Quantum Dots (QDs) and the reactions of organic substances to create an olfactory-inspired sensing system based on the mammalian olfactory framework. Our primary aim was to identify the complex composition of volatile organic com- pounds (VOCs) found in cigarette smoke. We designed an innovative optical olfaction device to categorize various VOCs emitted by cigarettes. We utilized advanced techniques like Unsupervised Independent Compo- nent Analysis (ICA) and supervised Linear Discriminant Analysis (LDA) for robust data analysis. The LDA yielded remarkable results, with 100% precision in both the training and cross-validation phases. To validate our system, we rigorously assessed its ability to distinguish between five different cigarette brands, achieving 100% precision in training and an im- pressive 85% during cross-validation. Using LDA, we also conducted a comprehensive analysis of 100 sam- ples of four popular Indian cigarette brands (Gold Fake, Four Square, Navy Cut, ITC Classic), including authentic and counterfeit variants, resulting in a commendable 97% accuracy. Our analytical protocol is efficient, cost-effective, user-friendly, and highly reliable. The remarkable selectivity of our sensor array makes it indispensable for detecting genuine and counterfeit cigarettes, providing crucial support for global border control efforts.
Thermal Comfort Conditions of an Indoor Hot-Climate Swimming Pool
Authors: Mohamed Houssameldin M. , Sadeq Abdellatif M. , Sleiti Ahmad K. , Ahmed Samer F. 
Published: December 2023

Abstract
This study thoroughly investigates thermal comfort conditions within an indoor swimming pool in a desert climate resembling the climatic conditions of regions like Qatar, known for its scorching summers and mild winters. The research focuses on a 17.6 m x 11.7 m indoor swimming pool, assessing its response to extreme outdoor conditions: 43.3 ℃ dry-bulb temperature and 33.3 ℃ wet bulb temperature for summer, and 17 ℃ dry-bulb temperature and 10.6 ℃ wet bulb temperature for winter. Design considerations maintain indoor temperatures in the range of 24 to 29 ℃ year-round, aligning with ASHRAE Handbook recommendations for indoor swimming pools. The study encompasses a comprehensive analysis, including calculation of pool evaporation rates and resulting latent heat load gain. Hourly Analysis Program (HAP 4.9), a specialized cooling load calculation program, was employed to determine the essential thermal load required to maintain optimum indoor conditions. Computational Fluid Dynamics (CFD) simulations, employing ANSYS Fluent 19.2 and incorporating standard turbulence and moisture content models following a meticulous grid independence study, were conducted. The results highlight distinct average indoor conditions for both summer and winter, encompassing parameters such as air temperature, air velocity, and relative humidity. The research outcomes, assessed using Predicted Mean Vote (PMV) and Predicted Percentage of Dissatisfied (PPD), indicate comfort in summer and slight warmth in winter, serving as a valuable reference for future research on desert pool and greenhouse designs, ultimately enhancing indoor environmental quality.
Characteristics that Increase the Risk for Pain on Propofol Injection
Authors: Leff Phillip J , Dinner Brett , Chuang Keng-Yu , Leff David 
Published: December 2023

Abstract
Background: Propofol for anesthesia has become increasingly popular for endoscopic procedures. However, pain on propofol injection (POPI) remains an issue with administration. The goal of this study was to identify patient characteristics, which could be predictive as to who will experience POPI.
Methods:This was a prospective chart review study of 291 patients undergoing endoscopic procedures. Patient’s demographics, intravenous (IV) site, and gauge were extrapolated. POPI was scored 0-3: 0 for no pain, 1 for minimal discomfort or awareness of sensation, 2 for discomfort but manageable/tolerable, and 3 for severe discomfort with writhing.
Results:291 patient charts were reviewed. One patient excluded for a lower extremity IV site. 225 (77.6%) had no pain, 48 (16.6%) grade 1 pain, 16 (5.5%) grade 2 pain, and 1 (0.3%) grade 3 pain. 137, 13, and 140 patients respectively had antecubital (AC), forearm, and hand IVs. Zero patients with an AC IV experienced a score greater than 1. Compared to AC, forearm IVs with pain of 2-3 had a univariate odds ratio (OR) 11.3 (0.66,1.92; p-value <0.001), and hand IVs had a univariate OR 18.8 (2.46,143.3; p-value <0.001) with a multivariable OR 15.2 (1.93,118.9; p-value 0.004). Patients with anxiety/depression and pain had a univariate OR 2.31 (1.09, 7.27; p-value 0.031) with a multivariable OR 2.85 (1.06, 7.74; p-value 0.039). SSRI/SNRI use had a univariate OR was 1.56 (0.57,4.28; p-value 0.38). Alcohol use had a univariate OR was 1.24 (0.39,3.91; p-value 0.71). Narcotic use had a Univariate OR 6.18 (1.49,25.6; p-value 0.012). Diabetic patients had a univariate OR of 1.42 (0.45,4.48; p-value 0.55). Chronic pain had a univariate OR 3.11 (1.04,9.28; p-value 0.042). Female sex had a univariate OR 0.98 (0.37,2.63; p-value 0.95).
Conclusion:This study identified potential characteristics for having POPI. The incidence of POPI was statistically significant in patients with hand and forearm IVs compared to AC IV sites, larger IV gauges, history of depression/anxiety, history of chronic narcotic use, fibromyalgia, and chronic pain syndromes. This shows the potential of premedicating with analgesics or using AC site on these select patients to help reduce the risk of POPI.
Endophytes: a uniquely tailored source of potential antibiotic adjuvants
Authors: Moussa Ashaimaa Y. 
Published: December 2023

Abstract
Multidrug microbial resistance is risking an annual loss of more than 10 million people’ lives by 2050. Solutions include the rational use of antibiotics and the use of drugs that reduce resistance or completely obliterate them. Several plant extracts were reported as active antimicrobial agents, but their supply problem and low rate of compound isolation retarded their advancement in this field. Here endophytes come to play due to their high yield production and inherent nature to produce antimicrobial molecules where 40%, 45% and 17% of antibacterial agents were obtained from fungi, actinomycetes, and bacteria, respectively, whose secondary metabolites revealed effectiveness against resistant microbes such as MRSA, MRSE, and Shigella flexneri. Endophyte’s role was not confined to bactericidal effect but extended to other mechanisms against MDR microbes, among which was the adjuvant role or the “magic bullets" that could revive obsolete antibiotics again. Scarce focus was given to antibiotic adjuvants, and many laboratories today just screen for the antimicrobial activity without considering combinations with traditional antibiotics, which means real loss of promising resistance combating molecules. This review, comprehensively and for the first time, sheds light on the significance of endophytes secondary metabolites in solving AMR problem as AB adjuvants.
Neural Network-based Prescribed Performance Fault-Tolerant Control for Spacecraft Formation Reconfiguration with Collision Avoidance
Authors: Jia Qingxian , Shu Rui , Yu Dan , Zhang Chengxi , Tan Lining 
Published: December 2023

Abstract
This article investigates the issue of neural network (NN)-based prescribed performance control with collision avoidance ability for a spacecraft formation system in presence of space perturbations and thruster faults. First, an artificial potential function is constructed to guarantee that spacecraft remain within communication range and collision-free. Then, a prescribed performance function is introduced such that the position errors are constrained within a preset boundary. Further, a learning non-singular terminal sliding mode control (LNTSMC) law is explored to ensure that the steady-state and transient performance of the position tracking errors satisfy the prescribed performance constraints. A novel learning NN model is utilized to estimate and compensate for the synthesized perturbation, in which an iterative learning algorithm is proposed to update the weights of the NN, reducing the computational burden. The proposed LNTSMC scheme can effectively solve issues of the inter-spacecraft collision avoidance, prescribed performance, and robust fault tolerance. Numerical simulations and comparisons are provided to demonstrate the effectiveness and superiority of the presented approach.
Study on the efficient adsorption of selenium(III) by hydroxyapatite composite zeolite imidazolium framework-67
Authors: Xu Dan , Qin Yuanyuan , Huang Yuhua , Wang Jiaming , Liu Xiao , Liu Feiyan , Li Xiancai , Cao Xiaohua 
Published: December 2023

Abstract
The enrichment and recovery of rare earth ions is an effective way to achieve sustainable utilization of wastewater resources. Using a simple ultrasound assisted synthesis method, nano hydroxyapatite (HAP) was introduced into ZIF-67 at room temperature to synthesize HAP/ZIF-67 composite materials with rich functional groups. XRD, FT-IR, SEM, XPS, and BET were used to characterize HAP/ZIF-67 composite materials. The effects of pH, time, adsorption dose, ambient temperature and initial concentration on the adsorbent were investigated by static repeated adsorption experiments. The results show that the synergistic effect of the Co-OH, -NH-, -C = N- functional groups in ZIF-67 and the Ca-OH and PO43− groups in nano-HAP improves the adsorption capacity of the composite material. It increased to 461.55mg/g, and the adsorption rate increased to 92.31%. They are 2.41 times higher than HAP and 1.55 times higher than ZIF-67. The adsorption characteristic of Ce3+ on HAP/ZIF-67 composites is more consistent with the Langmuir isotherm model and pseudo-second-order model, which indicate a single-layer, surface-homogeneous chemisorption process for Ce(Ⅲ) adsorption. The adsorption process is a spontaneous heat absorption process according to thermodynamic research. The main mechanism of HAP/ZIF-67 adsorption of Ce(Ⅲ) is surface complexation. After four elution experiments, HAP/ZIF-67 adsorbent has good reusability, indicating that HAP/ZIF-67 is a promising adsorbent in the field of rare earth ion recovery.
Pharmacotherapy Versus Exercise for Management of Low Back Pain: a Network Meta-analysis
Authors: Nweke Martins , Obarisiagbon Osayi Nkiru , Onyeso Ogochukwu , Imo Uzunma Portia 
Published: December 2023

Abstract
Background/aims: Use of pharmacological agents for low back pain (LBP) is more popular than physical exercises due to convenience, and administrative easiness. However, it is unclear whether pharmacotherapy is superior to exercises. The study aimed to examine efficacy of pharmacotherapy versus physical exercises for LBP.
Materials/Methods: This is a network meta-analysis of randomized and non-randomised trials. We searched MEDLINE, PubMed, CINAHL, Academic Search Complete, and PsycINFO for articles published in English on use of pharmacotherapy and/or exercise in LBP management. Initial title, abstract screening and extraction were done following a predefined eligibility criteria. We used random-effect model of meta-analysis to estimate efficacy of pharmacotherapy and exercise, and network meta-analysis to compare their separate efficacies. We appraised quality of the included studies with aid of Cochrane Risk of Bias 1 and 2.
Results: Relative to placebo, there were significant reductions in pain intensity with both pharmacotherapy (SMD = -0.769, 95% CI = -1.290-0.248, I2 = 96.634) and exercises (SMD = -1.563, CI = -2.784-0.342, I2 = 93.701). Direct comparison of pharmacotherapy and exercise showed insignificant reduction in pain intensity amongst individuals who received exercise compared to pharmacotherapy and exercise (SMD= -0.138, CI = -0.384 – 0.660). Indirect comparison showed no significant difference between pharmacotherapy and acupuncture (SMD = 0.023 (CI = -0.688 to 0.733). Overall, in favour of exercise, we obtained a combined estimate of SMD = -0.483 = (CI =-2.059 to 1.093).
Conclusions: Exercise appears superior to pharmacotherapy for LBP, however exercise may not always be a preferred option.
Chronology or Context: Temporality and Artificiality of Museum Collections
Authors: Cvjetićanin Tatjana 
Published: December 2023

Although museum collections represent a temporary assemblage of “affiliated objects”, aimed at facilitating the responsible curation of the museum funds, in practice they are treated as an obligatory unit, without which the museum object itself does not exist, and they are imminently permanent. The origins, as well as the consequences of their formation may differ.
The text examines several issues concerning the artificiality and temporality of collections: what are the values we observe when museum collections are formed, are these values transparent and permanent? Which attributes are con- sidered as crucial bythe curators in the classification of archaeological material and are these classifications consistent?
Does chronology/periodization prevail in practice and how are the boundaries between the periods established? Is context preserved or, more precisely, is an object attributed along with the other artefacts from the same unit, which was carefully separated during excavation? What or whoinfluences the processes of formation of museum collections?
The analysis is conducted on the case of the National Museum of Serbia, the oldest and the main museum institution, primarily because the archaeological objects form its basic fund ever since its establishment in 1844. Today, there are several hundred-thousand objects, organized into 16 basic collections and study material. Along with the obligatory authenticity, dating is most frequently the basic principle on which classifications are based, concerning period, origin, or typological systematization. Chronology – period/sequence – is also the main criterion of the permanent museum exhibitions, and necessary to custodians inmediating the disciplinary knowledge.
Custodians “re-arrange” the past, starting from a museum object and collection, creating specific units of museum(archaeological) time – time capsules, frozen reconstructions, new realities. The museum may thus be understood as a contextdetermined by multi-temporality, or the co-existence of different times.
Furthermore, working from the idea of Bennet (2009) that the museum may be identified as “the field”, it can also be interpreted as a “multi-layered site”. Various actors – object, collection, custodian, public – contribute to the accumulated character of the record. The “museum layering” is determined by the diversity of the criteria of acquisition, various attributes of classification, the artificiality of collections, transitionary value of objects, as well as personally and socially determined interpretations.