bluuebunny/crossref_metadata_2025_split huggingface dataset:
COMUNICAÇÃO EM CUIDADOS PALIATIVOS NAS UNIDADES DE TERAPIA INTENSIVA: UMA REVISÃO INTEGRATIVA
Authors: Rodrigues Lutigard Feitosa , Costa Brunna Hellen Saraiva , Caldeira Natalia Rosa e Souza , Paletot Yolanda Abrantes , Marcella de Moura Batista  , Nepomuceno Adriana Meira Tiburtino , Melo Geni Kelly Araújo Silva , De Jesus Juliana Alves , De Moura-Ferreira Maria Cristina , Moreira Maria Eliane , Pereira Francilene Jane Rodrigues 
Published: February 2024

Introdução: A prática clínica tem demonstrado acentuado despreparo das equipes de saúde em lidar com pacientes/familiares em cuidados paliativos no contexto da comunicação, agravando-se nos cenários das Unidades de Terapia Intensiva. Destarte, toma-se por objetivo caracterizar as publicações científicas brasileiras sobre o processo de comunicação na perspectiva dos cuidados paliativos nas Unidades de Terapia Intensiva. Materiais e Método: Utilizou-se da revisão integrativa realizada nos meses de abril e maio de 2019, incluindo estudos publicados entre os anos de 2008 e 2018. Resultados: Obteve-se um total de nove artigos, sendo a maior parte deles (66,7%) artigos originais delimitados em duas categorias temáticas: dificuldades no processo de comunicação entre a equipe de saúde e pacientes/familiares e a comunicação enquanto ferramenta terapêutica. Discussão: observou-se como dificuldades, a falta de habilidade na transmissão de más notícias bem como a supervalorização do aparato tecnológico; enquanto ferramenta terapêutica mostrou-se capaz de reduzir sintomas físicos e emocionais e proporcionar sensação de conforto e; dentre os desafios, destacou-se a falta de interação da equipe entre si e com pacientes/familiares, a falta de treinamentos específicos para aprimoramento dessa habilidade, a não priorização no cotidiano assistencial e ainda, a centralização do ato na figura do médico e/ou psicólogo. Conclusão: apesar do incipiente quantitativo de estudos disponíveis, possibilitou sintetizar os conhecimentos acerca da comunicação em cuidados paliativos nas Unidades de Terapia Intensiva levantando dados relevantes acerca das dificuldades, possibilidades e desafios no contexto da comunicação.
O corpo dançante na escola pela leitura do literário: uma experiência estética
Authors: Steil Isleide , Neitzel Adair de Aguiar 
Published: February 2024

Este artigo tem como objetivo tecer relações entre corpo, dança e a leitura do literário que são produzidas no espaço da escola, por meio da obra literária Grande Sertão: Veredas de Guimarães Rosa. É um estudo de abordagem qualitativa, que utilizou a metodologia Pesquisa Educacional Baseada em Arte (PEBA): A/r/tografia. Os sujeitos da pesquisa foram alunos do contraturno escolar, do 6º ao 9º ano do Ensino Fundamental, de uma Escola Básica da Rede Municipal de Ensino de Itajaí, SC. A produção dos dados deu-se em 11 oficinas de dança, tendo como objeto propositor a literatura. Os resultados apontam que o corpo dançante pode fazer uma experiência pela leitura do literário com mediações culturais adequadas que provoquem a relação entre obra e corpo, motivando os sujeitos a pensar e a sentir em como seus corpos se movimentam e se relacionam com a obra, com os outros e com o espaço.
Entre a luta e o abandono
Authors: Veronese Osmar , Specht Lemos da Silva Daiane 
Published: February 2024

A seletividade e precariedade dos estabelecimentos prisionais brasileiros revelam uma sociedade excludente e desigual, situação intensificada ao tratar sobre a mulher no cárcere, visto que a prisão foi criada por homens e para homens. No breu do breu, as mulheres são esquecidas, muito provavelmente, pelo legado da cultura patriarcal que predomina na sociedade, ao colocar a mulher em segundo plano. Dessa forma, o tema do presente estudo é a mulher encarcerada, delimitado em abordar o seu abandono também em razão dos resquícios do patriarcado e da dominação masculina. Como objeto principal, bem como pergunta norteadora tem-se: em que medida a herança do patriarcado (im)possibilita a ausência de reconhecimento e legitima a violação de direitos das mulheres encarceradas? Em busca de respostas, o artigo se estrutura em duas partes. A primeira, enfoca questões ligadas à liberdade das mulheres e os resquícios do patriarcado, fazendo uma sondagem quanto ao perfil da mulher encarcerada, bem como sua condição de (in)visibilidade, com a ausência de reconhecimento e reificação. A segunda, dialoga sobre a dignidade da pessoa humana e as condições atuais dos estabelecimentos prisionais. Quanto à metodologia empregada tem-se o método dedutivo analítico, com base de dados em pesquisa bibliográfica de doutrinadores que estudam a temática, na legislação e em dados/estatísticas da Organização Mulheres em Prisão. A abordagem encontra eco no fato de que, de um modo geral, a situação desigual da mulher na sociedade se agrava com a condenação à pena privativa de liberdade, consolidando comportamentos culturais desiguais e excludentes, os quais precisam ser denunciados e revertidos.
Evaluasi Kerasionalan penggunaan Antibiotik Pada Pasien ISPaA Usia Balita Di Puskesmas Ketapang Kota Tangerang Periode Januari-Desember 2022
Authors: Fadjariah Siti , Panduwiguna Ivans , Nugrahini Lestari 
Published: February 2024

ISPA adalah penyakit menular yang menginfeksi saluran pernafasan manusia yang disebabkan oleh mikroorganisme seperti bakteri, jamur dan virus. Pengobatan ISPaA yang disebakan oleh bakteri diatasi dengan menggunakan antibiotik. Metode penelitian adalah deskriptif dengan pengumpulan data secara retrospektif. Sampel yang gunakan sebanyak 154 rekam medis yang memenuhi kriteria inklusi. Pederita ISPaA dengan jenis kelamin laki-laki sebanyak 79 (51%) dan jenis kelamin perempuan sebanyak 75 (49%). interval usia 2-3 tahun sebanyak 101 (66%) dan interval usia 4-5 tahun sebanyak 53 (49%).Antibiotik yang digunakan pada pengobatan ISPaA Balita paling banyak Amoksisilin sebesar 152 (99%) dan Kotrimoksazole sebanyak 2 (1%). Evaluasi rasionalisasi penggunaan antibiotik pasien ISPaA, yaitu 100% tepat pasien , 100% tepat obat, 100%tepat indikasi, dan 90% tepat dosis.

Kata Kunci: ISPaA, Balita, antibiotik
Calidad de vida y sarcopenia en adultos mayores
Authors: Chiroy Muñoz Rosa Julia , Muñoz-Valle José Francisco 
Published: February 2024

Introducción: El adulto mayor posee capacidad funcional si puede realizar sus labores, aún con uso de apoyos como bastones o andadores; su salud se ve condicionada por su historial de vida, presencia de fragilidad o de sarcopenia, enfermedades crónicas, recursos económicos, oportunidad de acceso al sistema de salud y la asistencia médica oportuna que le permita una vida digna. Objetivo: Describir de forma general la relación de la Categoría Internacional del Funcionamiento en adultos mayores con sarcopenia y su calidad de vida. Métodos: Como buscador de información científica se utilizó a Google Académico, las palabra clave empleadas fueron sarcopenia, longevidad, calidad de vida y categoría de funcionamiento. Fueron evaluados documentos de investigación provenientes de bases de datos: PubMed, Scielo e Hinari, que en general tenían menos de 10 años de publicación, en idioma español o inglés, con adecuada calidad metodológica; se excluyeron artículos que no concordaban con los objetivos del estudio. Se revisaron 89 referencias con el gestor Mendeley versión v1.59.0, únicamente citadas 44. Conclusiones: La sarcopenia es un síndrome geriátrico caracterizado por disminución de la masa, fuerza muscular y del rendimiento físico que repercute la calidad de vida. La evaluación de la calidad de vida y estadificación funcional son parte de la atención integral geriátrica.
A defesa do trabalho escravo por representantes do legislativo no Brasil contemporâneo: uma reflexão crítica urgente!
Authors: Pinto Maria Lídia Nogueira , De Souza Rosália Beber 
Published: February 2024

Este artigo se propõe a analisar os discursos dos políticos brasileiros Sandro Fantinel e Luiz Philippe de Orleans e Bragança em relação à problemática do trabalho análogo à escravidão. Utilizando a abordagem teórico-metodológica de Norman Fairclough (2003), renomado autor na Análise Crítica do Discurso, buscou-se investigar as estruturas linguísticas que não apenas comunicam, mas também representam e modificam o mundo físico e social. Destacamos a capacidade desses discursos em moldar perspectivas e perpetuar o status quo em relação à classe hegemônica econômica. Como produto da interação social, demonstramos como o discurso pode influenciar os valores e as práticas sociais, sustentando práticas de abusos e desrespeitos aos Direitos Fundamentais ou modificá-los a partir de uma reflexão crítica ao desvelar as naturalizações.
Direct, Continuous Behavioral Analysis of Drug Action on Feeding
Authors: Goodson Simon , Halford Jason , Blundell John 
Published: November 2004

AbstractAnalysis of rodent feeding behavior during the study of anorectic drugs reveals that contextual variables such as type of food, drug, environment, and physiological state influence food intake. Temporal changes in behavior can signal the onset of a feeding modulation process, as is the case with anorectic drugs acting on distinct neurochemical mechanisms that change temporal behavioral profiles. Comparing the effects of anorectic agents in controlled animal assays can identify potential therapeutic drugs that may influence human eating behavior. This unit specifies the materials and procedures required for continuously monitoring the Behavioral Satiety Sequence, as well as a device for continuous, automatic measurement of the mass of food consumption by the animal during behavioral monitoring called the RUEMA (Rat Universal Eating Monitor Apparatus).
Animal Models of Painful Diabetic Neuropathy: The STZ Rat Model
Authors: Morrow Thomas J. 
Published: November 2004

AbstractPainful peripheral neuropathy is a common secondary complication of diabetes. The streptozotocin (STZ)‐induced diabetic rat is the most commonly employed animal model used to study mechanisms of painful diabetic neuropathy and to evaluate potential therapies. A low dose STZ protocol is described for inducing experimental diabetes in the rat. Several behavioral assays are described, which are routinely used to assess different aspects of neuropathic pain in this animal model of diabetes mellitus, including mechanical allodynia and heat hyperalgesia.
Identification of Human Antigen‐Specific T Cells Using MHC Class I and Class II Tetramers
Authors: Krueger Lori A. , Nugent C. Thomas , Hampl Johannes 
Published: November 2004

AbstractMajor histocompatibility complex (MHC) tetramers typically consist of a fluorophore‐streptavidin complex and biotinylated soluble MHC molecules carrying a peptide of interest. Tetramers bind to T cell receptors (TCR) that recognize the MHC molecule/peptide combination with high specificity. Native MHC molecules are expressed as cell‐surface glycoproteins capable of binding a variety of peptides generated from the degradation of self and non‐self proteins for display to T cells. The human MHC gene locus is highly polymorphic, with >800 class I and >500 class II alleles currently identified. This heterogeneity contributes to the uniqueness of each person's immune system. This unit describes procedures for labeling CD8+ T cells with MHC class I tetramers and CD4+ T cells with MHC class II tetramers. The protocols can be used for detecting and enumerating human antigen‐specific T cells. Both CD8+ and CD4+ antigen‐specific T cells are rare events and require that sufficient numbers of cells be evaluated. To minimize nonspecific tetramer binding contributed by irrelevant cell populations, a cumulative gating strategy using positive selection and/or exclusion gating is described.
Changing profile of couples seeking genetic counseling for consanguinity in Australia
Authors: Port Katrina E. , Mountain Helen , Nelson John , Bittles Alan H. 
Published: November 2004

AbstractConsanguineous marriage is rare in most Western countries and, for example, in the USA it may be subject to regulation by both civil legislation and religious proscription. This is not the case in many regions of Asia and Africa where marriage within the family is strongly favored. Since the 1970s there has been widespread migration to North America, Western Europe, and Australasia from communities which encourage consanguineous marriage. To assess the effect of this trend on a genetic counseling program, the records of 302 couples referred to Genetic Services of Western Australia for consanguinity counseling were abstracted for the period 1975–2001. Overall, a family history of genetic disease or a previously affected child was reported in 28.8% of cases. Premarital or prepregnancy counseling on grounds of consanguinity was sought by 41.0% of couples, and a further 18.2% of consanguineous couples had been referred because of a consanguineous pregnancy. In 7.6% of cases a relationship closer than first cousin was involved. Through time there was a significant increase in the numbers of consanguineous consultands, and their patterns of religious affiliation and ethnic origin widened markedly. Although effectively excluded from entry to Australia prior to 1975, couples of Asian origin accounted for 25.5% of all consanguineous consultands. With ongoing migration, changes in the ethnic profiles and the specific counseling requirements of consanguineous couples can be expected to continue and probably accelerate. © 2004 Wiley‐Liss, Inc.
Blood expression profiles for tuberous sclerosis complex 2, neurofibromatosis type 1, and down's syndrome
Authors: Tang Yang , Schapiro Mark B. , Franz David N. , Patterson Bonnie J. , Hickey Francis J. , Schorry Elizabeth K. , Hopkin Robert J. , Wylie Matthew , Narayan Tina , Glauser Tracy A. , Gilbert Donald L. , Hershey Andrew D. , Sharp Frank R. 
Published: November 2004

AbstractBlood gene expression profiling has been applied to a variety of hematological malignancies, autoimmune disorders, and infectious diseases. This study applies this approach to genetic diseases without obvious blood phenotypes. Three genetic diseases including tuberous sclerosis complex 2, neurofibromatosis type 1, and Down's syndrome were compared with a group of healthy controls. RNA from whole blood was surveyed using Affymetrix U133A arrays. Each disease was associated with a unique gene expression pattern in blood that can be accurately distinguished by a classifier. Genes on chromosome 21 were overexpressed in Down's syndrome, and genes controlling cell cycle and proliferation were associated with tuberous sclerosis complex type 2 or neurofibromatosis type 1. A subset of genes involved in cardiac development or remodeling were overexpressed in patients with Down's syndrome and congenital heart defects. These findings suggest that blood gene expression profiling on a broader basis might be useful for genetic disease screening/diagnosis and might help elucidate mechanisms and pathways that lead to genotype–phenotype differences. Ann Neurol 2004
Reorganization in congenital hemiparesis acquired at different gestational ages
Authors: Staudt Martin , Gerloff Christian , Grodd Wolfgang , Holthausen Hans , Niemann Gerhard , Krägeloh‐Mann Ingeborg 
Published: November 2004

AbstractIt is well established that the reorganizational potential of the developing human brain is superior to that of the adult brain, but whether age‐dependent differences exist already in the prenatal and perinatal period is not known. We have studied sensorimotor reorganization in 34 patients with congenital hemiparesis (age range, 5–27 years), using transcranial magnetic stimulation and functional magnetic resonance imaging during simple hand movements. Underlying pathologies were brain malformations (first and second trimester lesions; n = 10), periventricular brain lesions (early third trimester lesions; n = 12), and middle cerebral artery infarctions (late third trimester lesions; n = 12). Of this cohort, eight patients with malformations and all patients with periventricular lesions have been published previously. In all three groups of pathologies, transcranial magnetic stimulation identified patients in whom the paretic hand was controlled via ipsilateral corticospinal projections from the contralesional hemisphere (n = 16). In these patients, the motor dysfunction of the paretic hand correlated significantly with the timing period of the underlying brain lesion. This demonstrates that the efficacy of reorganization with ipsilateral corticospinal tracts indeed decreases during pregnancy. Ann Neurol 2004
Separation of organic compounds binding trace elements in seeds of Leuzea carthamoides (Willd.) DC
Authors: Pavliková Daniela , Pavlík Milan , Vašičková Soňa , Száková Jiřina , Tlustoš Pavel , Vokáč Karel , Balík Jiří 
Published: November 2004

AbstractThe distribution of trace elements into important groups of compounds in seeds was investigated using a seven‐step sequential extraction of seed biomass (solvents used: petroleum ether, ethyl acetate, butanol, methanol, methanol + H2O (1 + 1; v/v), H2O, methanol + H2O + HCl (49.3 + 49.3 + 1.4; v/v/v)). Isolated fractions were partially characterized using IR spectroscopy. Results of sequential analysis showed different portions of the elements investigated in individual fractions. The dominant portions of cadmium (60.6% of total content), lead (41%), zinc (77.8%) and copper (33.9%) were found in the methanol + H2O + HCl fractions (compounds isolated from cell walls and cytoskeleton after hydrolysis—phytic acid and its salts, proteins). The second most significant fractions for cadmium, zinc and lead were in the water fractions (pectin, phytin) and for copper in the methanol fraction (acids of citric cycle). The ethyl acetate fraction, mainly containing lignans and phospholipids, had the highest portion of arsenic (34.2%). Lignans are common compounds for seeds of Leuzea carthamoides. Therapeutic compounds of L. carthamoides (20‐hydroxyecdysone, N‐feruloylserotonin isomers) were confirmed in the first four fractions by thin‐layer chromatography. Copyright © 2004 John Wiley & Sons, Ltd.
Investigations into the role of methylcobalamin and glutathione for the methylation of antimony using isotopically enriched antimony(V)
Authors: Wehmeier Silvia , Raab Andrea , Feldmann Jörg 
Published: November 2004

AbstractGlutathione (γ‐GluCysGly, GSH) and methylcobalamin (CH3‐B12) may play a role in the biomethylation process of antimony. To understand better the transformation of antimony in biological systems, we studied abiotic and biomethylation processes and the influence of GSH in the methylation.CH3‐B12, acting as a possible methylating agent for antimony, was studied with GSH and in the absence of GSH. The most abundant product of this reaction was monomethylantimony, with a small concentration of the dimethylantimony species, as identified by hydride generation cryotrapping gas chromatography inductively coupled plasma mass spectrometry (HG‐CT‐GC‐ICP‐MS). In the same experiments we found that tris(γ‐GluCysGly)trithioantimonite [Sb(GS)3] and di(γ‐GluCysGly)methyldithioantimonite [(CH3)Sb(GS)2] complexes were present using flow‐injection electrospray ionization MS. Both complexes were also identified in a fermented sewage sample, suggesting that these complexes may play a role as intermediates in the biomethylation of antimony.However, CH3‐B12 is not the sole methylation agent, since it does not produce any trimethylantimony species as identified in anaerobic sewage sludge cultures inoculated with enriched 123Sb(V). Species‐specific 123/121Sb isotope ratio measurements of the different methylantimony species suggest a stepwise methylation of antimony according to the Challenger mechanism. Copyright © 2004 John Wiley & Sons, Ltd.
Water absorption and mechanical properties of electrospun structured hydrogels
Authors: Hansen Laura M. , Smith Daniel J. , Reneker Darrell H. , Kataphinan Woraphon 
Published: November 2004

AbstractElectrospun nanofibers are made when electrostatic forces overcome the surface tension of a polymer solution, causing an electrically charged jet to be ejected; as the jet travels through the air, the solvent evaporates, leaving behind an electrically charged fiber, which can be collected in the form of a nonwoven sheet. A superabsorbent was added to a polymer solution containing an elastomer (concentrations = 0–85%). The mixture was electrospun, producing nanofibers in which the superabsorbent particles were held in place with nanoscale elastic fibers. The nanofibers were tested for absorbency in water and synthetic urine. Fluid absorption by the nanofibers led to the formation of structured hydrogels. Increases in the weight gain from water absorption ranged from 400 to 5000%. The linear dimensions of samples cut from the nonwoven sheet were measured; wetting the superabsorbent increased the thickness dimension of the sheet dramatically and produced a smaller change in the plane of the sheet. The rate of water absorption was calculated; the samples containing 0–70% superabsorbent reached essentially their maximum absorbency within 5 s. The excellent strength and elasticity of the wet samples make these structured hydrogels ideal for many uses, including wound care, drug delivery, and sanitary goods. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 95: 427–434, 2005
Photocuring of a thiol‐ene system based on an unsaturated polyester
Authors: Kim Y. B. , Kim H. K. , Choi H. C. , Hong J. W. 
Published: November 2004

AbstractTo produce a photocurable thiol‐ene system, unsaturated polyester was prepared from the condensation reaction of ethylene glycol, diethylene glycol, and fumaric acid. Diallyl groups were introduced into the ends of the unsaturated polyester by a sequential condensation reaction. The coating formulation studied contained an equimolar ratio of thiol and vinyl groups of the prepared unsaturated polyester, including 1 wt % Irgacure 184. The curing behaviors of the unsaturated polyester with multifunctional thiols were investigated using real‐time FTIR spectroscopy. The rates of disappearance of thiol and vinyl groups of the unsaturated polyester were similar, demonstrating that there was little free‐radical homopolymerization of the internal fumaric group or the end‐capped vinyl ether group during the photocuring process and that the thiol‐ene reaction is the dominant process. The kinetics of the model compounds demonstrated that the reaction of the terminal allyl double bond with the thiyl radical is faster than that of the internal fumaric double bond in the UV curing of the unsaturated polyester. The storage stability of the thiol‐ene system based on unsaturated polyester was effectively increased by the addition of N‐PAL. The Raman spectra revealed that the presence of a multifunctional thiol (penta 3‐MP4) in the coating formulation increased the degree of surface curing due to the chain‐transfer ability of the thiyl radical. © 2004 Wiley Periodicals, Inc. J Appl Polym Sci 95: 342–350, 2005