bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation and conversion of flavour related compounds of thermal cooked Ruditapes philippinarum soup
Authors: Li Jinyu , Ma Yunjiao , Xiao Feng , Fu Baoshang , Xu Xianbing 
Published: September 2023

SummaryThermal reactions affect flavour, but how different thermal reactions influence the flavour of cooked soup has rarely been investigated. Herein, the effect of heat treatment (0–50 min) at different temperatures (120, 140 and 160 °C) on Ruditapes philippinarum soup was studied. The acceptable heating of Ruditapes philippinarum soup was assigned at 140 °C for 30 min by human sensory evaluation and compound analysis. In addition, the detailed relationship between the formation of key volatile compounds and heating temperature was revealed by partial least squares discriminant analysis (PLS‐DA) and the odour coding method. A total of 28 key volatile compounds were selected according to the results of variables important in the projection (VIP) and odour activity value (OAV). Whereas 3‐ethyl‐2,5‐dimethyl pyrazine and 2‐heptylfuran were the most important volatiles produced only in the thermal reaction at 140 °C and associated with cocoa and roasted nut odours. These results indicated the relationship between thermal reactions and flavour formation. The odour coding obtained from OAV could be as a reference benchmark for heating seafood soup products.
Highly efficient blue‐emitting phosphor via charge compensation strategy and its application for white LED lighting
Authors: Xu Yonghui , Yin Shuwen , Wu Xiudi , Zhong Chuansheng , Zhang Xibao , Zhou Liang , You Hongpeng 
Published: September 2023

AbstractHighly efficient phosphors are indispensable for near‐ultraviolet (n‐UV) pumped white light emitting diodes (WLEDs). In this work, a novel blue emitting Sr6GdSc(BO3)6:0.08Ce3+ phosphor was synthesized, exhibiting a broadband blue emission (full width at half‐maximum (FWMH) = 133 nm) excited by 375 nm. Furthermore, the blue emission of Sr6GdSc(BO3)6:0.08Ce3+ was enhanced by 3.9 times through codoping Na+ ions due to the influence of charge compensation and micromorphology and size of phosphor particles. At the same time, the internal quantum efficiency was improved from 45.4% to 98.6% and the external quantum efficiency up to 75.0%. Finally, the 365 nm excited two WLED devices were constructed by integrating Sr6GdSc(BO3)6:0.08Ce3+, Sr6GdSc(BO3)6:0.08Ce3+,0.08Na+, commercial green and red phosphors with high color rendering index. These results reveal that the phosphors have prospective application in high‐quality warm white lighting.
Improved ferroelectricity and magnetoelectric coupling effect of multielements co‐substituted BiFeO3 ceramics
Authors: Liu Lu , Zhu Xiao Li , Chen Xiang Ming 
Published: September 2023

AbstractIn the present work, the strategy of multielements co‐substitution for BiFeO3 ceramics was adopted to enhance the ferroelectricity and magnetoelectric coupling effect where the effective radius of rare‐earth ions was equivalent to that of Sm3+. Differing from the case of Sm‐substituted BiFeO3 ceramics, the symmetry of the present ceramics changed from R3c to Pbnm directly without the formation of Pna21 with increasing RE‐substitution content. The ferroelectricity was significantly improved, and the saturated polarization−electric field (P‐E) hysteresis loop with Pr = 37.63 μC/cm2 was obtained in Bi0.95(La0.20Nd0.20Sm0.20Gd0.20Lu0.20)0.05FeO3 ceramics. The leakage current was reduced by almost six orders of magnitude in multielements co‐substituted BiFeO3 ceramics, which was much lower than that of BiFeO3 end‐member. Moreover, the magnetoelectric coupling coefficient αME of 0.96 mV/cm Oe was achieved in Bi0.86(La0.20Nd0.20Sm0.20Gd0.20Lu0.20)0.14FeO3 ceramics, which was larger than that of Sm‐substituted BiFeO3 ceramics. The strategy of multielements co‐substitution might provide a new approach to improving ferroelectricity and magnetoelectric coupling effect in BiFeO3 ceramics, which could be physically interpreted as the results of the reduced leakage current and increased local polarization configuration caused by the multiple elements substitution.
Potential sources of time lags in calibrating species distribution models
Authors: Essl Franz , García‐Rodríguez Adrián , Lenzner Bernd , Alexander Jake M. , Capinha César , Gaüzère Pierre , Guisan Antoine , Kühn Ingolf , Lenoir Jonathan , Richardson David M. , Rumpf Sabine B. , Svenning Jens‐Christian , Thuiller Wilfried , Zurell Damaris , Dullinger Stefan 
Published: September 2023

AbstractThe Anthropocene is characterized by a rapid pace of environmental change and is causing a multitude of biotic responses, including those that affect the spatial distribution of species. Lagged responses are frequent and species distributions and assemblages are consequently pushed into a disequilibrium state. How the characteristics of environmental change—for example, gradual ‘press’ disturbances such as rising temperatures due to climate change versus infrequent ‘pulse’ disturbances such as extreme events—affect the magnitude of responses and the relaxation times of biota has been insufficiently explored. It is also not well understood how widely used approaches to assess or project the responses of species to changing environmental conditions can deal with time lags. It, therefore, remains unclear to what extent time lags in species distributions are accounted for in biodiversity assessments, scenarios and models; this has ramifications for policymaking and conservation science alike. This perspective piece reflects on lagged species responses to environmental change and discusses the potential consequences for species distribution models (SDMs), the tools of choice in biodiversity modelling. We suggest ways to better account for time lags in calibrating these models and to reduce their leverage effects in projections for improved biodiversity science and policy.
Early recurrences predict late therapy failure after pulsed field ablation of atrial fibrillation
Authors: Plank Karin , Bordignon Stefano , Urbanek Lukas , Chen Shaojie , Tohoku Shota , Schaack David , Hirokami Jun , Efe Tolga , Chun K.R. Julian , Schmidt Boris 
Published: September 2023

AbstractIntroductionPulsed field ablation (PFA) is a new ablation technology for atrial fibrillation (AF). Data regarding early recurrences of atrial tachyarrhythmia (ERAT) after PFA‐pulmonary vein isolation (PVI) are sparse.MethodsConsecutive patients with symptomatic AF were enrolled to undergo PFA‐PVI. A dedicated catheter delivering bipolar energy (1.9–2.0 kV) was used. Late recurrence (LR) was defined as documented AF/atrial tachycardia (AT) lasting more than 30 s after a 90‐day blanking period.ResultsTwo hundred and thirty‐one patients (42% female, age 69 ± 12, 55% paroxysmal AF [PAF]) were included in this analysis. Median follow‐up time was 367 days (interquartile range: 253–400). Forty‐six patients (21%) experienced ERAT after a median of 23 days (46% in PAF and 54% in persistent AF [persAF]). Kaplan–Meier estimated freedom of AF/AT was 74.2% at 1 year, 81.8% for PAF, and 64.8% for persAF (p = .0079). Of patients experiencing ERAT, an LR was observed in 54%. There was no significant difference of LR between those who presented with very early ERAT (0–45 days) and those with ERAT (46–90 days) (p = .57). In multivariate analysis, ERAT (hazard ratio [HR]: 3.370; 95% confidence interval [95% CI]: 1.851–6.136; p < .001) and female sex (HR: 2.048; 95% CI: 1.114–3.768; p = .021) were the only independent predictors for LR.ConclusionsERAT could be recorded in 21% of patients after PFA‐PVI and was an independent predictor for LR. We found no difference in the rate of LRs among patients experiencing ERAT before or after 45 days.
Atrial fibrillation recurrences during the blanking period after catheter ablation with the laser balloon technique
Authors: Schiavone Marco , Gasperetti Alessio , Martignani Cristian , Montemerlo Elisabetta , Ciconte Giuseppe , Ziacchi Matteo , Arosio Roberto , Piazzi Elena , Spadotto Alberto , Ruggiero Diego , Angeletti Andrea , Pozzi Mattia , Biffi Mauro , Rovaris Giovanni , Forleo Giovanni Battista 
Published: September 2023

AbstractIntroductionRegardless of the catheter ablation (CA) for atrial fibrillation (AF) strategy, the role of early recurrences during the blanking period (BP) is still unclear. Our aim was to evaluate atrial tachyarrhythmias (ATAs) recurrences during the BP after CA with the laser‐balloon (LB) technique.MethodsConsecutive patients undergoing LBCA were enrolled. Primary outcome of the study was the overall crude ATA recurrence rate during the BP. ATA recurrences after the BP and in‐hospital readmissions during the BP were deemed secondary outcomes.ResultsTwo hundred and twenty‐four patients underwent CA with the LB. Median age was 63.0 (55.5–69.5) years and 74.1% were males. 28.6% were persistent AF patients, and 34.8% of patients were followed up with a loop recorder. 15.6% of patients experienced at least an ATA recurrence during the BP. Male sex, chronic heart failure, persistent AF, and recurrences during the BP were found to be associated with long‐term ATA recurrences. Recurrences during the BP remained associated with the outcome of interest at multivariate analysis (hazard ratio [HR] = 12.393, 95% confidence interval [95% CI] = 3.699–41.865, p < .001). An association over time was found between early and late recurrences, with 73.7%, 45.5%, and 10.8% of patients presenting with recurrences at 1‐, 2‐, and 3‐month follow‐up being free from recurrences after the BP, respectively. 8.0% of patients were readmitted during the BP: 4.5% for AF electrical cardioversion, and 1.8% for CA of other atrial arrhythmias; no redo CA was performed.ConclusionAfter adjusting for confounders, ATA recurrences during the BP represent the most significant predictor of ATA recurrences after the BP, regardless of AF pattern.
Complex decision making in an intensive care environment: Perceived practice versus observed reality
Authors: Teele Sarah A. , Tremoulet Patrice , Laussen Peter C. , Danaher‐Garcia Nicole , Salvin Joshua W. , White Bobbie Ann A. 
Published: September 2023

AbstractRationaleAdvancing our understanding of how decisions are made in cognitively, socially and technologically complex hospital environments may reveal opportunities to improve healthcare delivery, medical education and the experience of patients, families and clinicians.Aims and ObjectivesExplore factors impacting clinician decision making in the Boston Children's Hospital Cardiac Intensive Care Unit.MethodsA convergent mixed methods design was used. Quantitative and qualitative data sources consisted of a faculty survey, direct observations of clinical rounds in a specific patient population identified by a clinical decision support system (CDSS) and semistructured interviews (SSIs). Deductive and inductive coding was used for qualitative data. Qualitative data were translated into images using social network analysis which illustrate the frequency and connectivity of the codes in each data set.ResultsA total of 25 observations of eight faculty‐led interprofessional teams were performed between 12 February and 31 March 2021. Individual patient characteristics were noted by faculty in SSIs to be the most important factor in their decision making, yet ethnographic observations suggested faculty cognitive traits, team expertise and value‐based decisions were more heavily weighted. The development of expertise was impacted by role modeling. Decisions were perceived to be influenced by the system and environment.ConclusionsClinician perception of decision making was not congruent with the observed behaviours in a complicated and dynamic system. This study identifies important considerations in clinical curricula as well as the design and implementation of CDSS. Our method of using social network analysis to visualize components of decision making could be adopted to explore other complex environments.
Connection abstract theory: An exercise in abstract theorizing after Bowlby
Authors: Bell David C. 
Published: September 2023

AbstractThis paper proposes connection abstract theory as a detailed abstract formulation of the volitional elements of John Bowlby's theory of child attachment and its expansion to include adult relationships. Connection abstract theory is a formal statement of causal connections within and between attachment and caregiving systems. It is so‐called to give an unambiguous name to the attachment–caregiving relationship. The analysis addresses some limitations traceable to the cultural background within which Bowlbian theory was developed. This paper rethinks these limitations by conceptualizing the emotional motivations for attachment and caregiving. In so doing, it goes beyond individual differences to focus on microfoundations of normative attachment and caregiving processes and expands the potential activators of attachment. Connection abstract theory asserts that caring is the emotion that motivates the caregiving system and that trust is the emotion that motivates the attachment system.
Shamanic alliance in the touristic borderzone: Strategic hospitality at Surama Eco‐Lodge in Guyana
Authors: Whitaker James Andrew 
Published: September 2023

AbstractThis article explores how villagers in Surama form alliances with outsiders through strategic hospitality within the touristic borderzone. Surama is a primarily Makushi village in Guyana. Tourism began during the 1990s and is now central to the village economy. Villagers' efforts to form relationships with certain visitors (particularly tourist leaders) as partners or yakos through hospitality reflect an ontological framework associated with shamanism. This involves relational modes of interaction that are common across Amazonia but have been underexamined in the context of tourism. However, Makushi alliances with outsiders in Surama are unique in their emphasis on mutuality and symmetry, which stems from past Makushi experiences of enslavement during the colonial encounter and antipathy towards asymmetric relations. Based on fieldwork involving interviews and participant observation in Surama, this article links debates in Amazonian ethnology and the anthropology of tourism to examine how villagers in Surama manage relations with tourists to obtain external resources.
Increasing Rates of Human Papillomavirus Catch‐Up Vaccination at a Sexual and Reproductive Health Clinic: A Quality Improvement Project
Authors: Pfingstag C. Shannon 
Published: September 2023

IntroductionCatch‐up human papillomavirus (HPV) vaccination of adults aged 19 to 26 who were not vaccinated as children or adolescents may decrease rates of HPV‐associated cancer. The purpose of this project was to increase uptake of catch‐up HPV vaccination at a sexual and reproductive health clinic through the implementation of a multicomponent, systems‐based intervention.ProcessCatch‐up vaccination rates were recorded at an intervention health clinic and a comparison health clinic. A comparative, interrupted time series design was used to compare rates of catch‐up vaccination pre‐ and postintervention. Electronic health record prompts, in‐clinic education, and scheduling of a next visit at the current visit were implemented. Data were analyzed using descriptive statistics, t tests, and regression analysis.OutcomesThe proportion of all patients aged 19 to 26 who received an HPV vaccination rose at the intervention health clinic from 0.76% preintervention to 4.42% postintervention. At the intervention clinic there was a nonsignificant increase (4.47 minutes) in average daily patient cycle times between the pre‐ and postintervention periods (t(13) = 1.895, P = .075).DiscussionRates of catch‐up HPV vaccination increased significantly following the multicomponent, systems‐based intervention. Further iteration of the quality improvement process should examine the sustainability of the interventions and the effects of the intervention on vaccine series completion.
The Birth Bundle Project: A Rainier Valley Midwifery‐led Collaborative Care Initiative Offering Patients and Providers a Paradigm Shift to Impact Health Equity
Authors: Lawal Tara K. , Owen Jodilyn , Brown Andi Garcia , Effland Kristin J. 
Published: September 2023

AbstractInnovative midwifery‐led collaborative care models have the potential to build on grassroots approaches to make transformative change within systems that work with families. Rainier Valley Midwives operates the Birth Bundle Project, a successful program that serves communities who are at higher risk for poor birth outcomes and face barriers to adequate medical, prenatal, and postpartum care, including Black, Indigenous, and persons of color. This project offers wraparound perinatal care services to provide a missing community of support to traditionally marginalized families before, during, and after birth while also bridging the gaps between midwives and physicians who attend births in different settings. By strengthening and formalizing the relationships between different types of perinatal providers including community‐based doulas and lactation support professionals, this midwifery‐led initiative improves the continuity and quality of care available to families including immigrant, refugee, and families of color in south Seattle, Washington.
Effect of customized abutment taper configuration on bone remodeling and peri‐implant tissue around implant‐supported single crown: A 3D nonlinear finite element study
Authors: Poovarodom Pongsakorn , Rungsiyakull Chaiy , Suriyawanakul Jarupol , Li Qing , Sasaki Keiichi , Yoda Nobuhiro , Rungsiyakull Pimduen 
Published: September 2023

AbstractPurposeThe optimal configuration of a customized implant abutment plays a crucial role in promoting bone remodeling and maintaining the peri‐implant gingival contour. However, the biomechanical effects of abutment configuration on bone remodeling and peri‐implant tissue remain unclear. This study aimed to evaluate the influence of abutment taper configurations on bone remodeling and peri‐implant tissue.Materials and methodsFive models with different abutment taper configurations (10°, 20°, 30°, 40°, and 50°) were analyzed using finite element analysis (FEA) to evaluate the biomechanical responses in peri‐implant bone and the hydrostatic pressure in peri‐implant tissue.ResultsThe results demonstrated that the rate of increase in bone density was similar in all models. On the other hand, the hydrostatic pressure in peri‐implant gingiva revealed significantly different results. Model 10° showed the highest maximum and volume‐averaged hydrostatic pressures (69.31 and 4.5 mmHg), whereas Model 30° demonstrated the lowest values (57.83 and 3.88 mmHg) with the lowest excessive pressure area. The area of excessive hydrostatic pressure decreased in all models as the degree of abutment taper increased from 10° to 30°. In contrast, Models 40° and 50° exhibited greater hydrostatic pressure concentration at the cervical region.ConclusionIn conclusion, the abutment taper configuration had a slight effect on bone remodeling but exerted a significant effect on the peri‐implant gingiva above the implant platform via hydrostatic pressure. Significant decreases in greatest and average hydrostatic pressures were observed in the peri‐implant tissues of Model 30°. However, the results indicate that implant abutment tapering wider than 40° could result in a larger area of excessive hydrostatic pressure in peri‐implant tissue, which could induce gingival recession.
Hypoxia dissociates HDAC6/FOXO1 complex and aggregates them into nucleus to regulate autophagy and osteogenic differentiation
Authors: Xu Yixin , Wang Yixin , Xiao Hui , Li Yongming 
Published: September 2023

AbstractObjectiveThis research aimed to elucidate the molecular mechanisms underlying the periodontitis‐associated bone loss, with particular emphasis on the contributory role of hypoxic microenvironment in this process.BackgroundPeriodontitis generally causes alveolar bone loss and is often associated with a hypoxic microenvironment, which affects bone homeostasis. However, the regulating mechanism between hypoxia and jaw metabolism remains unclear. Hypoxia triggers autophagy, which is closely related to osteogenic differentiation, but how hypoxia‐induced autophagy regulates bone metabolism is unknown. HDAC6 and FOXO1 are closely related to bone metabolism and autophagy, respectively, but whether they are related to hypoxia‐induced bone loss and their internal mechanisms is still unclear.MethodsEstablished rat nasal obstruction model and hypoxia cell model. Immunohistochemistry was performed to detect the expression and localization of HDAC6 and FOXO1 proteins, analysis of autophagic flux and transmission electron microscopy was used to examine the autophagy level and observe the autophagosomes, co‐immunoprecipitation and chromatin immunoprecipitation were preformed to investigate the interaction of HDAC6 and FOXO1.ResultsHypoxia causes increased autophagy and reduced osteogenic differentiation in rat mandibles and BMSCs, and blocking autophagy can attenuate hypoxia‐induced osteogenic differentiation decrease. Moreover, hypoxia dissociated the FOXO1‐HDAC6 complex and accumulated them in the nucleus. Knocking down of FOXO1 or HDAC6 alleviated hypoxia‐induced autophagy elevation or osteogenic differentiation reduction by binding to related genes, respectively.ConclusionHypoxia causes mandibular bone loss and autophagy elevation. Mechanically, hypoxia dissociates the FOXO1‐HDAC6 complex and aggregates them in the nucleus, whereas HDAC6 decreases osteogenic differentiation and FOXO1 enhances autophagy to inhibit osteogenic differentiation.
Clinical diagnosis and outcome of cervicofacial cellulitis in pyrexic rabbits: six cases (2014‐2021)
Authors: Tournade C. , Dusick A. , Mans C. 
Published: September 2023

ObjectivesTo assess the signalment, history, exam findings, diagnostics, treatment and outcome of rabbits diagnosed with pyrexia and concurrent cervicofacial cellulitis.Materials and MethodsRetrospective evaluation of medical records of rabbits diagnosed with cervicofacial cellulitis and pyrexia based on physical exam, contrast‐enhanced CT, clinicopathology and microbiology findings.ResultsSix out of 1588 rabbits met the study inclusion criteria. Rabbits presented with a median age of 6 years (range, 8 months to 8 years) with a presenting complaint of anorexia or hyporexia. All rabbits had a rectal temperature >40.2°C (104.4°F). Physical exam and contrast‐enhanced CT revealed unilateral submandibular and ipsilateral cervical diffuse soft tissue swelling in five of six rabbits. No antemortem evidence of periodontal or dental disease was found on physical exam or CT. Leucopenia was present in five of six rabbits. A left shift with marked toxic changes was present in all four rabbits, for which blood smears were reviewed. Bacterial cultures of the aspirated subcutaneous soft tissue swelling culturedEscherichia coli,Pasteurella multocida,Granulicatella adiacens,Streptococcusspecies,Haemophilusspecies andBacteroidesspecies. Treatment was pursued in five rabbits, where all rabbits received supportive care and four of five rabbits received systemic antibiotics. One rabbit was euthanased following a diagnosis of cervicofacial cellulitis. Three out of five rabbits continued to decline clinically despite medical management, and thus, euthanasia was pursued within 24 hours of starting treatment. Two rabbits responded to initial treatment and developed subsequent multi‐focal abscessation. One rabbit was euthanased due to client cost constraints, and one rabbit died shortly after achieving clinical resolution of cervicofacial cellulitis.Clinical SignificanceCervicofacial cellulitis should be considered a differential diagnosis in pyrexic rabbits with facial or cervical swelling with medical and surgical management pursued for therapy.