bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of cardiorespiratory fitness level with vascular function and subclinical atherosclerosis in the elderly
Authors: Größer Vincent , Weyh Christopher , Böttrich Tim , Frech Torsten , Nolte Svenja , Sommer Natascha , Huber Magdalena , Eder Klaus , Dörr Oliver , Hoelscher Sophie , Weber Rebecca , Akdogan Ebru , Nef Holger , Most Astrid , Hamm Christian W. , Krüger Karsten , Bauer Pascal 
Published: December 2023

Abstract
Purpose
Physical exercise is crucial for healthy aging and plays a decisive role in the prevention of atherosclerotic cardiovascular disease (ASCVD). A higher level of cardiorespiratory fitness (CRF) in the elderly is associated with lower cardiovascular and all-cause mortality. This study investigated the association of CRF level with vascular function and cardiovascular risk factors in the elderly.

Methods
We examined 79 apparently healthy and physically active subjects aged > 55 years (64 ± 4 years). Cardiovascular functional parameters assessed included brachial and central blood pressure (BP), pulse wave velocity (PWV), augmentation index (Aix), and ankle-brachial index. Sonography of the common carotid artery was performed. CRF level was determined by a cardiopulmonary exercise test, and everyday activity was quantified with an accelerometer.

Results
All participants had a higher CRF level than the reported age-specific normative values. Twenty-nine subjects had subclinical atherosclerosis of the common carotid artery. Compared with participants without atherosclerosis, they were older (p = 0.007), displayed higher brachial systolic BP (p = 0.006), and higher central systolic BP (p = 0.014). Lower brachial (p = 0.036) and central (p = 0.003) systolic BP, lower PWV (p = 0.004), lower Aix (p < 0.001), lower body fat percentage (< 0.001), and lower LDL cholesterol (p = 0.005) were associated with a higher CRF level.

Conclusions
In this cohort of healthy and physically active individuals, subjects with subclinical atherosclerosis displayed higher systolic brachial and central BP. A higher CRF level was associated with enhanced vascular function, consistent with an influence of CRF on both BP and vascular function in the elderly.
Physiological mechanisms associated with the use of a passive heat intervention: positive implications for soccer substitutes
Authors: Cowper Gavin , Goodall Stuart , Hicks Kirsty M. , Burnie Louise , Fox Kai T. , Keenan Ashleigh , De Martino Enrico , Briggs Marc A. 
Published: December 2023

Abstract
Purpose
Soccer substitutes are exposed to periods of limited activity before entering match-play, likely negating benefits of active warm-ups. This study aimed to determine the effects of using a passive heat intervention following a pre-match, and half-time warm-up, on muscle and core temperature in soccer players during ambient (18 °C) and cold (2 °C) conditions.

Methods
On four occasions, 8 male players, completed a pre-match warm-up, followed by 45 min of rest. Following this, participants completed a half-time re-warm-up followed by an additional 45 min of rest, simulating a full match for an unplaying substitute. During periods of rest, participants wore either standardised tracksuit bottoms (CON), or heated trousers (HEAT), over typical soccer attire.

Results
Vastus lateralis temperature declined less in HEAT compared to CON following the 1st half in 2 °C (Δ − 4.39 ± 0.81 vs. − 6.21 ± 1.32 °C, P = 0.002) and 18 °C (Δ − 2.48 ± 0.71 vs. − 3.54 ± 0.88 °C, P = 0.003). These findings were also observed in the 2nd half for the 2 °C (Δ − 4.36 ± 1.03 vs. − 6.26 ± 1.04 °C, P = 0.002) and 18 °C (Δ − 2.85 ± 0.57 vs. − 4.06 ± 1 °C, P = 0.018) conditions. In addition, core temperature declined less in HEAT compared to CON following the 1st (Δ − 0.41 ± 0.25 vs. − 0.84 ± 0.41 °C, P = 0.037) and 2nd (Δ − 0.25 ± 0.33 vs. − 0.64 ± 0.34 °C, P = 0.028) halves of passive rest in 2 °C, with no differences in the 18 °C condition. Perceptual data confirmed that participants were more comfortable in HEAT vs. CON in 2 °C (P < 0.01).

Conclusions
Following active warm-ups, heated trousers attenuate the decline in muscle temperature in ambient and cold environments.
Validation of the DIGEST-FEES as a Global Outcome Measure for Pharyngeal Dysphagia in Parkinson’s Disease
Authors: Labeit Bendix , Lapa Sriramya , Muhle Paul , Suntrup-Krueger Sonja , Claus Inga , Gandor Florin , Ahring Sigrid , Oelenberg Stephan , Dziewas Rainer , Warnecke Tobias 
Published: December 2023

AbstractFlexible Endoscopic Evaluation of Swallowing (FEES) is one of two diagnostic gold standards for pharyngeal dysphagia in Parkinson's disease (PD), however, validated global outcome measures at the patient level are widely lacking. The Dynamic Imaging Grade of Swallowing Toxicity for Flexible Endoscopic Evaluation of Swallowing (DIGEST-FEES) represents such an outcome measure but has been validated primarily for head and neck cancer collectives. The objective of this study was, therefore, to investigate the validity of the DIGEST-FEES in patients with PD. Content validity was evaluated with a modified Delphi expert survey. Subsequently, 66 FEES videos in PD patients were scored with the DIGEST-FEES. Criterion validity was determined using Spearman's correlation coefficient between the DIGEST-FEES and the Penetration-Aspiration Scale (PAS), the Yale-Residue-Rating-Scale, the Functional-Oral-Intake-Scale (FOIS), and the swallowing-related Unified-Parkinson-Disease-Rating-Scale (UPDRS) items. Inter-rater reliability was determined using 10 randomly selected FEES-videos examined by a second rater. As a result, the overall DIGEST-FEES-rating exhibited significant correlations with the Yale-Valleculae-Residue-Scale (r = 0.84; p < 0.001), the Yale-Pyriform-Sinus-Residue-Scale (r = 0.70; p < 0.001), the FOIS (r =  − 0.55, p < 0.001), and the UPDRS-Swallowing-Item-Score (r = 0.42, p < 0.001). Further, the DIGEST-FEES-safety subscore correlated with the PAS (r = 0.63, p < 0.001). Inter-rater reliability was high for the overall DIGEST-FEES rating (quadratic weighted kappa of 0.82). Therefore, DIGEST-FEES is a valid and reliable score to evaluate overall pharyngeal dysphagia severity in PD. Nevertheless, the modified Delphi survey identified domains where DIGEST-FEES may need to be specifically adapted to PD or neurological collectives in the future.
Total edge irregularity strength for special types of square snake graphs
Authors: Salama F. , Rafat H. , Attiya H. 
Published: December 2023

AbstractOne of the extremely useful branches in graph theory is the labeling of a graph. Graph labeling plays a vital role in many fields such as database management, astronomy, coding theory, X-ray crystallography, communication network addressing and radar. A labeling of a connected simple graph $$G\left( {V,E} \right)$$

G

V
,
E

is a map that assign each element in $$G$$
G
with a positive integer number. An edge irregular total $$\lambda^{\!\!\!\!\!-}$$

λ

-

-labeling is a map $$\beta :V\left( G \right) \cup E\left( G \right) \to \left\{ 1,2,3, \ldots ,\lambda^{\!\!\!\!\!-} \right\}$$

β
:
V

G

∪
E

G

→

1
,
2
,
3
,
…
,

λ

-

such that $$W_\beta \left( h \right) \ne W_\beta \left( z \right)$$

W
β

h

≠

W
β

z

where $$W_\beta \left( h \right)$$

W
β

h

and $$W_\beta \left( z \right)$$

W
β

z

are weights for any two distinct edges. In this case, $$G$$
G
has total edge irregularity strength (TEIS) if $$\lambda^{\!\!\!\!\!-}$$

λ

-

is minimum. In this paper, a new family of graphs called square snake graphs is defined and denoted by $$C_{4,n}$$

C

4
,
n

. Moreover, we define some related graphs of square snake graphs named double square snake graph $$D\left( {C_{4,n} } \right)$$

D

C

4
,
n

, triple square snake graph $$T\left( {C_{4,n} } \right)$$

T

C

4
,
n

and $$m$$
m
-multiple square snake graph $$M_m \left( {C_{4,n} } \right)$$

M
m

C

4
,
n

. Finally, we determine TEIS for square snake graphs, double square snake graph, triple square snake graph and $$m$$
m
-multiple square snake graph, which have many applications in coding theory and physics.
Geochemistry and geochronology of the Neyshabur meta-volcanic rocks, Binalood mountains, NE Iran: witnesses of Paleo-Tethys rifting and closure
Authors: Karimi Hadi , Topuz Gültekin , Ratschbacher Lothar , Shen Chuanbo , Li Jianhua 
Published: December 2023

Abstract
Geochemical and geochronologic data are presented for meta-mafic to meta-felsic rocks along the Paleo-Tethys Suture in the Binalood Mountains east of Neyshabur, NE Iran. The rocks have a late Cambrian age (U–Pb zircon, ~ 490 Ma) and were metamorphosed in the Early Jurassic (40Ar/39Ar amphibole and plagioclase, 199–192 Ma). The rocks of this suite are alkaline and sub-alkaline (tholeiitic). The alkaline rocks are enriched in light relative to heavy rare earth elements, and do not show depletion of high-field strength elements on primitive mantle-normalized multi-element diagrams; they are similar to ocean island basalts (OIB). The tholeiitic rocks are depleted in Nb and Ta and have higher MgO and lower TiO2 than the alkaline rocks. Both types have similar, high and variable 87Sr/86Sr(i) isotopic compositions of 0.7044 to 0.7082 and 143Nd/144Nd(i) values of 0.5118 to 0.5122. The alkaline rocks are lower-degree partial melts than the tholeiitic rocks and were generated at greater depths; they likely originated from a garnet pyroxenite-rich source. The spatial, temporal, and geochemical relationships of early Paleozoic meta-mafic to felsic rocks along the Paleo-Tethys Suture (e.g., Shahrud, Jajarm, Binalood, Torbat-e-Jam) substantiate the role of a mantle plume in continental breakup along the northern margin of Gondwana and a late Cambrian-Ordovician onset of rifting that resulted in the opening of the Paleo-Tethys Ocean. The Early Jurassic metamorphism post-dates its closure.

Graphical abstract
Children’s Responses to a Challenging Picturebook with a Contrapuntal Relationship Between Historical Facts and Humorous Fiction
Authors: Stranden Tone Louise , Ommundsen Åse Marie 
Published: December 2023

AbstractIn this article, the authors explore how Norwegian second-graders respond to the challenging picturebook, Min bestemor strøk kongens skjorter (My Grandmother Ironed the King’s Shirts) (Kove 2000). The cognitive challenges for the young readers lie in the picturebook’s humorous iconotext with a contrapuntal interplay between historical facts and fiction about World War II. In this classroom-based study, a reading event was designed to give the children an aesthetic experience with the picturebook and the possibility to explore it further. Each reading event included an opening in which the peritexts were discussed, a read-aloud (where two groups read the images on a Smart Board screen and two groups read the images in the physical book), an explorative dialogue, a creative workshop, and an ending. The analyzing process drew on Lawrence K. Sipe’s (Storytime: young children’s literary understanding in the classroom, Teachers College Press, New York, 2008) model of young children’s literary understanding and included an inductive analysis of the pupil’s responses that was inspired by a collective qualitative method (Eggebø in Norsk Sosiol Tidsskrift 4:106–122, 2020). On this basis, the authors present a model of children’s overlapping responses to a challenging picturebook. The pupils’ responses were embodied, creative, playful, analytical, personal and intertextual. Findings indicate that the reading event created a pleasurable aesthetic experience in which the children might develop tolerance for the complex fact-fiction relationship. The mediator’s facilitation and openness for a variety of responses and literary meaning-making during the reading event allowed the pupils to use their entire selves and express meaning-making in different ways. Findings indicate slightly more embodied responses and social interaction when the children read the pictures in the physical book rather than on the Smart Board screen.
Examining the relationship between regional economic resilience and epidemiologic spread of COVID-19: evidence from Greece
Authors: Tsiotas Dimitrios , Dialesiotis Stefanos , Christopoulou Olga 
Published: December 2023

AbstractThe experience of the COVID-19 pandemic has become a challenge worldwide for reconsidering the complex relationship between epidemiological vulnerability (EV) and regional economic resilience (RER). Building on statistical and empirical analysis, this paper detects that epidemiological vulnerability is positively related to geographical size, urbanization, economic size, and production capacity. The analysis distinguishes between the importance of the contribution of non-land transportation to epidemiological spread at the early stage of the pandemic, and of land transportation at later stages of the pandemic. It detects distinct spatiotemporal patterns in the distribution of epidemiological waves in Greek regions, illustrating a saturated temporal pattern and a “major” geographical configuration following the S-type dynamics of spatial development in Greece. Further, this paper highlights the importance of economies of scale and transportation connectivity in the configuration of the RER-EV nexus, emphasizing the significance of land transport connectivity for the control of neighborhood-scale socioeconomic activities once the pandemic is imported into a region. Finally, the analysis distinguishes land transport connectivity and urbanization degree as determinants related the most to long-term effects in the configuration of the RER-EV nexus and provides insights into the effectiveness of stringent policy measures implemented at the early stage of the pandemic. Overall, beyond its empirical case study, this paper provides a methodological framework to shed more light on a research field growing on the intersection of regional economics and public health and motivate more evidence-based policymaking enhancing the resilience of places in the face of future health crises.
Isotopic Evidence for Mobility in the Copper and Bronze Age Cemetery of Humanejos (Parla, Madrid): a Diachronic Approach Using Biological and Archaeological Variables
Authors: Cintas-Peña Marta , Garrido Pena Rafael , Herrero-Corral Ana M. , Flores Fernández Raúl , Waterman Anna J. , Díaz-Zorita Bonilla Marta , Díaz-del-Río Pedro , Peate David W. 
Published: December 2023

AbstractOver the last several decades, the application of aDNA and strontium isotope analyses on archaeologically recovered human remains has provided new avenues for the investigation of mobility in past societies. Data on human mobility can be valuable in the reconstruction of prehistoric residential patterns and kinship systems, which are at the center of human social organization and vary across time and space. In this paper, we aim to contribute to our understanding of mobility, residence, and kinship patterns in late Prehistoric Iberia (c. 3300–1400BC) by providing new strontium data on 44 individuals from the site of Humanejos (Parla, Madrid). The study presented here is multi-proxy and looks at these new data by interweaving biological, chronological, and archaeological information. This analysis found that 7/44 individuals buried at Humanejos could be identified as non-local to the necropolis. Although more men (n = 5) than women (n = 2) were found in the non-local category, and more non-local individuals were identified in the pre-Bell Beaker (n = 5) than in Bell Beaker (n = 1) or Bronze Age (n = 1), we find no statistically significant differences concerning sex or time period. This contrasts with other archaeological datasets for late prehistoric Europe which suggest higher female mobility, female exogamy, and male-centered residential patterns were common. At Humanejos, we have also identified one non-local female whose exceptional Beaker grave goods suggest she was an individual of special status, leading to additional questions about the relationships between gender, mobility, and social position in this region and time period.
Ethnic Minority Contact and the Similarities between Adolescent-Reported Parental and Self-Reported Far Right-Wing Attitudes
Authors: Haselbach Solveig , Beckmann Laura , Kliem Sören , Krieg Yvonne 
Published: December 2023

AbstractRecent developments in society, together with an increase in the number of far-right motivated crimes in Germany, suggest that far right-wing attitudes are becoming increasingly popular within public opinion. Since political attitudes are shaped within the family and peer setting during the adolescent stage, assessing the potential interplay of family and peer relationships with regard to such attitudes appears essential. The present study aims to explore (1) the relationship between perceived parental far right-wing attitudes, as reported by adolescents, and adolescents’ self-reported far right-wing attitudes, as well as (2) the unique and moderating effects of variables related to the contact hypothesis (ethnic minority friends and exposure to ethnic minority group members in the social environment). Using data from a representative school survey of seventh and ninth grade German adolescents, multilevel linear regression models indicated a statistically significant positive association between adolescent-reported parental far right-wing attitudes and adolescents’ far right-wing attitudes. Furthermore, the analyses demonstrated a small but statistically significant moderating effect of friendship with individuals of an ethnic minority: the relationship between parental and adolescent far right-wing attitudes was weaker for adolescents who had more ethnic minority friends. Thus, adolescents who were friends with individuals of an ethnic minority appeared to be less congruent with their parents’ far right-wing attitudes, compared to adolescents without any ethnic minority friends. In contrast, the overall level of exposure to ethnic minority group members in the social environment did not affect the strength of the relationship between perceived parental and adolescent far right-wing attitudes.
Prevalence and Characteristics of Non-tuberculous Mycobacteria (NTM) Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: a Systematic Review and Meta-analysis
Authors: Cinicola Bianca Laura , Ottaviano Giorgio , Hashim Ilie Fadzilah , Zainudeen Zarina Thasneem , Hamid Intan Juliana Abd , Elfeky Reem 
Published: December 2023

Abstract
Purpose
Non-tuberculous mycobacteria (NTM) infections in hematopoietic stem cell transplantation (HSCT) recipients represent a diagnostic and therapeutic challenge. Here, we aimed to review and analyze current literature on incidence, clinical presentation, and outcome of NTM infection after allogeneic HSCT.

Methods
We performed a systematic review and meta-analysis of available literature regarding NTM infection in children and adults receiving allogeneic HSCT.

Results
We identified 56 articles eligible for the analysis. Among 15 studies, describing 15,798 allogeneic HSCT, we estimated a prevalence of 1.26% (95% CI 0.72, 1.93) of NTM after transplant. Analysis of 175 patients with NTM infection showed a median time of diagnosis of 318 days after HSCT, an increased prevalence in adults (82.9%), and a most frequent pulmonary involvement (44%). Comparison between children and adults revealed an earlier post-transplant disease onset (median 130 days vs 287 days) and most frequent non-pulmonary presentation in children. A vast heterogeneity of therapeutic approach reflected the lack of universal recommendations regarding drug combination and duration of therapy. Overall, NTM-related mortality accounted for 33% in this systematic review.

Conclusion
Although rare, NTM infections can complicate post-transplant course with a high mortality rate in children and adults. The lack of prospective studies and guidelines prevents identification of risk factors and therapeutic recommendations.
logicDT: a procedure for identifying response-associated interactions between binary predictors
Authors: Lau Michael , Schikowski Tamara , Schwender Holger 
Published: December 2023

AbstractInteractions between predictors play an important role in many applications. Popular and successful tree-based supervised learning methods such as random forests or logic regression can incorporate interactions associated with the considered outcome without specifying which variables might interact. Nonetheless, these algorithms suffer from certain drawbacks such as limited interpretability of model predictions and difficulties with negligible marginal effects in the case of random forests or not being able to incorporate interactions with continuous variables, being restricted to additive structures between Boolean terms, and not directly considering conjunctions that reveal the interactions in the case of logic regression. We, therefore, propose a novel method called logic decision trees (logicDT) that is specifically tailored to binary input data and helps to overcome the drawbacks of existing methods. The main idea consists of considering sets of Boolean conjunctions, using these terms as input variables for decision trees, and searching for the best performing model. logicDT is also accompanied by a framework for estimating the importance of identified terms, i.e., input variables and interactions between input variables. This new method is compared to other popular statistical learning algorithms in simulations and real data applications. As these evaluations show, logicDT is able to yield high prediction performances while maintaining interpretability.
Mapping the flood hazard potential of small watercourses in a mountain river basin
Authors: Solín Ľubomír , Sládeková Madajová Michala , Michaleje Lukáš 
Published: December 2023

AbstractThis study presents a methodological approach for the mapping of the flood hazard potential of small watercourses, based on their hydromorphological attributes, on the example of a mountain river basin in Slovakia. The flood hazard of a watercourse is understood more comprehensively, providing a set of influencing variables and their attributes that affect the flood hazard. The proposed procedure consists of several steps ranging from the selection of stream variables influencing the flood hazard potential to the evaluation of the attributes of the variables in terms of their impacts on the flood hazard and the determination of a flood hazard index. The mapping divides the watercourse into reaches that differ by their level of flood hazard potential. This enables us to identify those river reaches that are critical in terms of flood hazard and that require management interventions. The results are interpreted in the context of cadastral areas through which the watercourses flow, which is particularly important for local authorities.