bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antecedents and consequences of procurement managers' willingness to pay for sustainability: a multi-level perspective
Authors: Khan Owais , Hinterhuber Andreas 
Published: January 2024

PurposeThe role of procurement managers is crucial for diffusing sustainability throughout the supply chain. Whether or not they are willing to pay for sustainability is an important and not yet fully understood question. The authors examine antecedents and consequences of their willingness to pay (WTP) for sustainability.Design/methodology/approachThe authors develop a multi-level framework to examine the WTP for sustainability in a B2B context. The authors test this multi-level framework with 372 procurement managers from multiple sectors and countries using partial least squares structural equation modeling.FindingsThe authors find that individual values of procurement managers and institutional pressures directly, while ethical organizational culture indirectly influence WTP for sustainability. Functional and cognitive competencies of procurement managers improve the sustainability of procurement, but not WTP for sustainability. Importantly, WTP for sustainability directly influences the performance of the procurement function which in turn is positively associated with increased organizational performance.Originality/valueThe study, examining the interplay between individual, organizational and contextual factors, provides empirical evidence on the pivotal role of procurement managers in diffusing sustainability throughout the supply chain. The findings of the study, on the one hand, contribute to the literature on operations management and sustainability, and on the other hand, guide policy and managerial actions.
Digital capabilities to manage agri-food supply chain uncertainties and build supply chain resilience during compounding geopolitical disruptions
Authors: Belhadi Amine , Kamble Sachin , Subramanian Nachiappan , Singh Rajesh Kumar , Venkatesh Mani 
Published: January 2024

PurposeThe agricultural supply chain is susceptible to disruptive geopolitical events. Therefore, agri-food firms must devise robust resilience strategies to hasten recovery and mitigate global food security effects. Hence, the central aim of this paper is to investigate how supply chains could leverage digital technologies to design resilience strategies to manage uncertainty stemming from the external environment disrupted by a geopolitical event. The context of the study is the African agri-food supply chain during the Russian invasion of Ukraine.Design/methodology/approachThe authors employ strategic contingency and dynamic capabilities theory arguments to explore the scenario and conditions under which African agri-food firms could leverage digital technologies to formulate contingency strategies and devise mitigation countermeasures. Then, the authors used a multi-case-study analysis of 14 African firms of different sizes and tiers within three main agri-food sectors (i.e. livestock farming, food-crop and fisheries-aquaculture) to explore, interpret and present data and their findings.FindingsDownstream firms (wholesalers and retailers) of the African agri-food supply chain are found to extensively use digital seizing and transforming capabilities to formulate worst-case assumptions amid geopolitical disruption, followed by proactive mitigation actions. These capabilities are mainly supported by advanced technologies such as blockchain and additive manufacturing. On the other hand, smaller upstream partners (SMEs, cooperatives and smallholders) are found to leverage less advanced technologies, such as mobile apps and cloud-based data analytics, to develop sensing capabilities necessary to formulate a “wait-and-see” strategy, allowing them to reduce perceptions of heightened supply chain uncertainty and take mainly reactive mitigation strategies. Finally, the authors integrate their findings into a conceptual framework that advances the research agenda on managing supply chain uncertainty in vulnerable areas.Originality/valueThis study is the first that sought to understand the contextual conditions (supply chain characteristics and firm characteristics) under which companies in the African agri-food supply chain could leverage digital technologies to manage uncertainty. The study advances contingency and dynamic capability theories by providing a new way of interacting in one specific context. In practice, this study assists managers in developing suitable strategies to manage uncertainty during geopolitical disruptions.
Institutional and organisational influence on mental health management in Spanish and Italian primary care
Authors: Giosa Roberto 
Published: January 2024

PurposeThis study aims to investigate how institutional and organisational factors affect case management of patients with mental disorders by GPs in Italy and Spain. The paper highlights the importance of improving the effectiveness of primary care to ensure easy access to mental health services, which is crucial in responding to the increasing incidence of mental disorders and preventing negative outcomes.Design/methodology/approachThis article details a qualitative research study that examines the management of patients with mental disorders by general practitioners (GPs) in Italy and Spain, using cross-national comparison and in-depth interviews with GPs as research methods.FindingsThe study revealed that Italian self-employed GPs have more scheduling autonomy than Spanish Health Centre GPs. Both face high work pressure and resource scarcity, highlighting the need for targeted training. The COVID-19 pandemic led to a rise in phone consultations.Originality/valueThis study provides novel insights into mental health management by examining the case management of patients with mental disorders by GPs in Italy and Spain, with a focus on the impact of institutional and organisational factors. The cross-national comparison and in-depth interviews enhance the originality of the study, offering a nuanced understanding of the constraints faced by GPs in their work context. Furthermore, the comparison of the similar primary care frameworks of Italy and Spain may offer insight into their evolution.
Social media as a behavior depolarizer: evidence from Russia–Ukraine conflict
Authors: Yadav Jitendra , Singh Kuldeep , Rana Nripendra P. , Dennehy Denis 
Published: January 2024

Purpose Social media has played a pivotal role in polarizing views on Russia–Ukraine conflict. The effects of polarization in online interactions have been extensively studied in many contexts. This research aims to examine how multiple social media sources may act as an integrator of information and act as a platform for depolarizing behaviors.Design/methodology/approach This study analyzes the communications of 6,662 tweets related to the sanctions imposed on Russia by using textual analytics and predictive modeling.Findings The research findings reveal that the tweeting behavior of netizens was depolarized because of information from multiple social media sources. However, the influx of information from non-organizational sources such as trending topics and discussions has a depolarizing impact on the user’s pre-established attitude.Research limitations/implications For policymakers, conflict mediators and observers, and members of society in general, there is a need for (1) continuous and consistent communication throughout the crisis, (2) transparency in the information being communicated and (3) public awareness of the polarized and conflicting information being provided from multiple actors that may be biased in the claims being made about the conflict crisis.Originality/value While previous research has examined Russia–Ukraine conflict from a variety of perspectives, this is the first study to examine how social media might be used to reduce attitude polarization during times of conflict.
AEKF-based trajectory-error compensation of knee exoskeleton for human–exoskeleton interaction control
Authors: Zhang Yuepeng , Cao Guangzhong , Li Linglong , Diao Dongfeng 
Published: January 2024

Purpose
The purpose of this paper is to design a new trajectory error compensation method to improve the trajectory tracking performance and compliance of the knee exoskeleton in human–exoskeleton interaction motion.

Design/methodology/approach
A trajectory error compensation method based on admittance-extended Kalman filter (AEKF) error fusion for human–exoskeleton interaction control. The admittance controller is used to calculate the trajectory error adjustment through the feedback human–exoskeleton interaction force, and the actual trajectory error is obtained through the encoder feedback of exoskeleton and the designed trajectory. By using the fusion and prediction characteristics of EKF, the calculated trajectory error adjustment and the actual error are fused to obtain a new trajectory error compensation, which is feedback to the knee exoskeleton controller. This method is designed to be capable of improving the trajectory tracking performance of the knee exoskeleton and enhancing the compliance of knee exoskeleton interaction.

Findings
Six volunteers conducted comparative experiments on four different motion frequencies. The experimental results show that this method can effectively improve the trajectory tracking performance and compliance of the knee exoskeleton in human–exoskeleton interaction.

Originality/value
The AEKF method first uses the data fusion idea to fuse the estimated error with measurement errors, obtaining more accurate trajectory error compensation for the knee exoskeleton motion control. This work provides great benefits for the trajectory tracking performance and compliance of lower limb exoskeletons in human–exoskeleton interaction movements.
Dihydromyricetin reverses capecitabine‐induced peripheral myelin dysfunction through modulation of oxidative stress
Authors: Fang Jie , Lou Shuyi , Zhou Xinyi , Lou Dayong , Zhou Liqin , Bian Rong 
Published: January 2024

AbstractPrevious clinical reports have shown that capecitabine, an oral prodrug of 5‐fluorouracil (5‐Fu), can induce peripheral neuropathy, resulting in numbness, paresthesia and hypoesthesia. However, the mechanism through which capecitabine causes peripheral nerve injury remains unclear. Here, we demonstrate that systemic administration of capecitabine leads to myelin abnormalities in the peripheral nerves of mice, which are possibly attributed to the death of Schwann cells, the myelinating cells in the peripheral nervous system. Furthermore, our results show that 5‐Fu induces significant oxidative stress in Schwann cells by inhibiting the expression of the anti‐oxidative protein DJ‐1, leading to a decrease in Schwann cell markers. We found that the anti‐oxidant dihydromyricetin (DMY) reverses 5‐Fu‐induced Schwann cell death and oxidative stress and alleviates capecitabine‐induced myelin abnormalities. Taken together, our data indicate that capecitabine induces peripheral myelin dysfunction by regulating DJ‐1‐mediated oxidative stress in Schwann cells and reveal DMY as a potential therapeutic strategy for capecitabine‐induced peripheral neuropathy.
Wolbachia effects on thermal preference of natural Drosophila melanogaster are influenced by host genetic background, Wolbachia type, and bacterial titer
Authors: Strunov Anton , Schönherr Charlotte , Kapun Martin 
Published: January 2024

AbstractTemperature plays a fundamental role in the fitness of all organisms. In particular, it strongly affects metabolism and reproduction in ectotherms that have limited physiological capabilities to regulate their body temperature. The influence of temperature variation on the physiology and behaviour of ectotherms is well studied but we still know little about the influence of symbiotic interactions on thermal preference (Tp) of the host. A growing number of studies focusing on the Wolbachia‐Drosophila host‐symbiont system found that Wolbachia can influence Tp in Drosophila laboratory strains. Here, we investigated the effect of Wolbachia on Tp in wild‐type D. melanogaster flies recently collected from nature. Consistent with previous data, we found reduced Tp compared to an uninfected control in one of two fly strains infected with the wMelCS Wolbachia type. Additionally, we, for the first time, found that Wolbachia titer variation influences the thermal preference of the host fly. These data indicate that the interaction of Wolbachia and Drosophila resulting in behavioural variation is strongly influenced by the genetic background of the host and symbiont. More studies are needed to better understand the evolutionary significance of Tp variation influenced by Wolbachia in natural Drosophila populations.
Testing the nuclear energy induced environmental Kuznets curve for Bulgaria: An ARDL bounds test with sharp and smooth breaks
Authors: Yilanci Veli , Syed Qasim Raza , Haouas Ilham 
Published: January 2024

AbstractAttaining sustainable development entails extensive use of clean energy and low levels of carbon emissions. Hence, nuclear energy is considered an avenue to reach higher levels of sustainable development. However, the existing literature documents the ambivalent conclusion on the nuclear energy‐emissions nexus. To solve this puzzle, the present study re‐investigates the nuclear energy‐emissions nexus for Bulgaria using the Environmental Kuznets Curve framework. We adopt the methodology of novel bootstrap ARDL with sharp and smooth structural breaks. The findings document that nuclear energy is responsible for waning emissions across the long and short‐run. Also, we validate the EKC hypothesis. To provide robust empirical findings, we perform a sensitivity analysis, which reports results similar to the baseline findings. Hence, we propose to escalate the adoption of nuclear energy to curb emissions.
Review article: Diagnosis and management of laryngopharyngeal reflux
Authors: Krause Amanda J. , Yadlapati Rena 
Published: January 2024

SummaryBackgroundLaryngopharyngeal reflux has classically referred to gastroesophageal reflux leading to chronic laryngeal symptoms such as throat clearing, dysphonia, cough, globus sensation, sore throat or mucus in the throat. Current lack of clear diagnostic criteria significantly impairs practitioners' ability to identify and manage laryngopharyngeal reflux.AimsTo discuss current evidence‐based diagnostic and management strategies in patients with laryngopharyngeal reflux.MethodsWe selected studies primarily based on current guidelines for gastroesophageal reflux disease and laryngopharyngeal reflux, and through PubMed searches.ResultsWe assess the current diagnostic modalities that can be used to determine if laryngopharyngeal reflux is the cause of a patient's laryngeal symptoms, as well as review some of the common treatments that have been used for these patients. In addition, we note that the lack of a clear diagnostic gold‐standard, as well as specific diagnostic criteria, significantly limit clinicians' ability to determine adequate therapies for these patients. Finally, we identify areas of future research that are needed to better manage these patients.ConclusionsPatients with chronic laryngeal symptoms are complex due to the heterogenous nature of symptom pathology, inconsistent definitions and variable response to therapies. Further outcomes data are critically needed to help elucidate ideal diagnostic workup and therapeutic management for these challenging patients.
Further delineation of the phenotypic and metabolomic profile of ALDH1L2‐related neurodevelopmental disorder
Authors: You Mikyoung , Shamseldin Hanan E. , Fogle Halle M. , Rushing Blake R. , AlMalki Reem H. , Jaafar Amal , Hashem Mais , Abdulwahab Firdous , Abdel Rahman Anas M. , Krupenko Natalia I. , Alkuraya Fowzan S. , Krupenko Sergey A. 
Published: January 2024

AbstractALDH1L2, a mitochondrial enzyme in folate metabolism, converts 10‐formyl‐THF (10‐formyltetrahydrofolate) to THF (tetrahydrofolate) and CO2. At the cellular level, deficiency of this NADP+‐dependent reaction results in marked reduction in NADPH/NADP+ ratio and reduced mitochondrial ATP. Thus far, a single patient with biallelic ALDH1L2 variants and the phenotype of a neurodevelopmental disorder has been reported. Here, we describe another patient with a neurodevelopmental disorder associated with a novel homozygous missense variant in ALDH1L2, Pro133His. The variant caused marked reduction in the ALDH1L2 enzyme activity in skin fibroblasts derived from the patient as probed by 10‐FDDF, a stable synthetic analog of 10‐formyl‐THF. Additional associated abnormalities in these fibroblasts include reduced NADPH/NADP+ ratio and pool of mitochondrial ATP, upregulated autophagy and dramatically altered metabolomic profile. Overall, our study further supports a link between ALDH1L2 deficiency and abnormal neurodevelopment in humans.
FOXL2 and NR5A1 induce human fibroblasts into steroidogenic ovarian granulosa‐like cells
Authors: Wen Fan , Ding Yuxi , Wang Mingming , Du Jing , Zhang Shen , Kee Kehkooi 
Published: January 2024

AbstractHuman granulosa cells in different stages are essential for maintaining normal ovarian function, and granulosa cell defect is the main cause of ovarian dysfunction. To address this problem, it is necessary to induce functional granulosa cells at different stages in vitro. In this study, we established a reprogramming method to induce early‐ and late‐stage granulosa cells with different steroidogenic abilities. We used an AMH‐fluorescence‐reporter system to screen candidate factors for cellular reprogramming and generated human induced granulosa‐like cells (hiGC) by overexpressing FOXL2 and NR5A1. AMH‐EGFP+ hiGC resembled human cumulus cells in transcriptome profiling and secreted high levels of oestrogen and progesterone, similar to late‐stage granulosa cells at antral or preovulatory stage. Moreover, we identified CD55 as a cell surface marker that can be used to isolate early‐stage granulosa cells. CD55+ AMH‐EGFP‐ hiGC secreted high levels of oestrogen but low levels of progesterone, and their transcriptome profiles were more similar to early‐stage granulosa cells. More importantly, CD55+ hiGC transplantation alleviated polycystic ovary syndrome (PCOS) in a mouse model. Therefore, hiGC provides a cellular model to study the developmental program of human granulosa cells and has potential to treat PCOS.
Generating modern heritage through changing urban environments and identities: A case study from Prato's (Italy) industrial district, history, and multiculturalism in a polycentric urban setting
Authors: Del Bianco Corinna 
Published: January 2024

AbstractFollowing economic crises, the evolution of industrial districts (IDs) has frequently caused the crisis within entire urban systems. Being IDs based on individual will and competences, rather than on big industries, their failure can compromise the city's identity. The Italian manufacturing industry consistently relied on this process, and this paper analyzes the case study of Prato, a medieval core city in central Italy that, since the mid‐twentieth century, developed a world‐class textile district based on a polycentric production structure and widespread family entrepreneurialism. During the global economic crisis of the early 2000s, production almost stalled, leaving the city without the core of a collective identity, but with a legacy of empty spaces. Significant foreign migration, in particular from China, filled these spaces, consolidating the clothing sector. The study investigated the city's contemporary identities resulting from the rapid change in people, activities, and spaces.
The image of modernity: An examination of early republic housing projects in Turkey 1930–1939
Authors: Sak Acur Mine 
Published: January 2024

AbstractModern heritage encompasses not only the physical structures but also the narratives, ideas, and sociohistorical dynamics associated with them. This study explores the multifaceted aspects of modern heritage in Turkey, focusing on early republic housing projects built between 1930 and 1939. Tracing the signs of being “modern” in residential architecture, this research proposes that Kemalist reforms affecting social life served as tools to alter appearances, and behind that image, the persistence of the cultural and social life was hidden. Analyzing projects in Arkitekt journal, it identifies traditional living patterns in so‐called modern houses, emphasizing the impossibility of copying‐and‐pasting modernity. In Turkey, modernity was neither unequivocally endorsed nor rejected; instead, it intertwined with existing social structures, creating a unique entity. Thus, it concludes that the value of early republic Turkish modern residentials lies not in formal similarities to European forms of modernism but in a transcultural understanding that embraces diverse expressions of modernity.
DNA metabarcoding and morphological identification reveal similar richness, taxonomic composition and body size patterns among flying insect communities
Authors: Remmel Nicole , Buchner Dominik , Enss Julian , Hartung Viktor , Leese Florian , Welti Ellen A. R. , Sinclair James S. , Haase Peter 
Published: January 2024

Abstract
Tracking insect biodiversity trends and predicting future trajectories is limited by a lack of monitoring data across large spatiotemporal scales. DNA metabarcoding is a time‐ and cost‐efficient method to obtain these data, but has several potential limitations in comparison to traditional morphological approaches. For example, metabarcoding may miss low‐abundance or smaller bodied individuals and is limited to presence/absence information, which may bias estimates of biodiversity and community composition. However, few comparisons of metabarcoding and morphology‐based identification have been made using insects, the by far most diverse animal taxonomic group.
Here, we compared terrestrial insect communities identified via morphology versus metabarcoding across four different habitats and three seasons (late spring, mid‐summer and early autumn) during 2019. We compared identified species and community richness, composition and body size, with a focus on key taxonomic groups of bees, true bugs, butterflies and hoverflies.
We identified 252 total species, with 54.8% identified by both methods, whereas 21.4% and 19.8% were solely detected with metabarcoding or morphology, respectively. Overall, total community richness, taxonomic composition and community body size were similar between methods. Metabarcoding detection successes declined in low‐abundance and smaller taxa, particularly bees, hoverflies and true bugs; however, species richness of hoverflies and butterflies tended to be higher compared with morphological identification.
Our results show that metabarcoding can provide an accurate overview of insect community differences that are comparable to those determined via morphological identification. We recommend that insect monitoring programmes consider incorporating metabarcoding, although future research is needed to overcome some remaining limitations.