bluuebunny/crossref_metadata_2025_split huggingface dataset:
Temporal structure of avian dawn chorus along an urbanization gradient
Authors: Godet Laurent , Prampart Abel , Lostanlen Vincent , Nabucet Jean , Aumond Pierre 
Published: October 2023

Abstract
Disentangling the relative influence of different anthropogenic pressures, landscape composition and biotic conditions on birdsong from species to community levels is challenging. On the basis of a field survey conducted on a breeding bird community in France, we measured the influence of such factors on the timing of birdsongs along an urbanization gradient. First, we found that species can be sorted according to different time song indices, and early singing species are also those with the largest eye sizes. For a given species, birds sing earlier and during shorter period in areas densely built, submitted to high levels of artificial lights, traffic noise, and in areas hosting the lowest conspecific abundances. At the community level, urbanization, and especially highly built and lit areas, leads to a community reassembly promoting late singing species and species singing for short periods. Finally, artificial lights and traffic noise promote a higher species temporal turnover and a lower temporal nestedness of the dawn chorus at the community level: different species tend to sing in a succession rather than in a polyphony. Our results suggest that the full bird chorus, gathering almost all the species singing together in the same time has thus disappeared in the most urbanized areas.
Serial Pattern Learning: Pigeons Prefer an Improving Schedule Over an Initially Easier Fixed Ratio Schedule
Authors: Ifraimov Miri , Peng Daniel N. , Zentall Thomas R. 
Published: October 2023

Abstract
Serial pattern learning describes behavior in which a subject anticipates not only the time and effort needed for the next reinforcer but also the pattern of time and effort to reinforcers after the first. Chandel et al. (2021) found that pigeons left a progressive schedule (in which each reinforcer was successively harder to obtain) earlier than would have been optimal. They argued that the pigeons anticipated the harder to obtain reinforcers beyond the next one. In the present experiments, pigeons were trained on a progressive schedule for which each reinforcer was successively easier to obtain but the initial choice was between a fixed ratio schedule (FR23) for which a reinforcer was easier to obtain than the first reinforcer on the improving progressive schedule (32 pecks). Delayed discounting suggests that the pigeons would prefer the FR23 because more immediate reinforcers should be preferred, whereas serial pattern learning suggests that the progressive schedule might be preferred because easier to obtain reinforcers would follow the initially harder 32 pecks. In Experiment 1, a preference (nonsignificant) for the progressive schedule was found. In Experiment 2, when the two alternatives were equated for the number of reinforcers that could be obtained on each trial, a significant preference for the improving progressive schedule was found. The results of both experiments were consistent with the serial pattern learning hypothesis. In both experiments the pigeons the pigeons did not choose the more immediate reinforcer associated with fixed ratio alternative. Rather they showed a preference for the improving progressive schedule for which later reinforcers would be easier to obtain.
Arabicization via loan translation: a corpus-based analysis of neologisms translated from English into Arabic in the field of information technology
Authors: Al-Athwary Anwar A. H. , Ali Husam K. 
Published: October 2023

Abstract
This article aims to use a corpus-based analysis to examine loan translation (LT) as an Arabicization technique in Written Standard Arabic (WSA) in the field of information technology (IT), and to investigate the factors that impact the formation of LTs. The data were collected from four distinct types of corpora: four Arabic online newspapers, the Microsoft Language Portal, two user manuals, and the Arabic Corpus of King Abdul-Aziz City for Science and Technology (KACST). Four LT strategies were identified: morphosyntactic pattern alteration, literal translation, loan blending, and metaphorical extension. Literal translation occurred in three degrees of calquing: full LTs, partial LTs, and non-LTs. Metaphors based on similarity in function play an important role in facilitating the understanding and acceptance of IT terms in WSA. The study also found that paradigmatic variation prevails in LTs, with synonymous variations being more common than nonsynonymous ones, and a total absence of syntagmatic variation. The KACST analysis showed that these variants differ a lot in terms of frequency of occurrence. The creation and variation of LTs are influenced by linguistic factors such as lexical need, semantic transparency, and lexical borrowing, as well as extralinguistic factors such as nationalism and the lack of coordination among Arabic language academies. The study concludes with some implications for overcoming the absence of coordination between these academies and for improving the quality of IT-related LTs between English and WSA.
The effect of educational intervention according to Mindfulness on the psychological well-being of female heads of households
Authors: Mahmoodi Fataneh , Zarnaghash Maryam , Shegefti Nadere Sohrabi , Barzegar Majid 
Published: October 2023

Abstract
Objective
Low level of psychological well-being is one of the most common problems of female heads of households, and various educational programs have been conducted to improve the psychological well-being of this group, the present study was conducted to develop the effect of educational intervention according to Mindfulness on the psychological well-being of female heads of households.
Methods
The method of this research was semi-experimental with a pretest-posttest design with a control group. The statistical population of the research included all female heads of households in Shiraz city who had a file in the Shiraz city welfare office and at the same time their children were studying in schools covered by the 2nd district education office of Shiraz city in 2022–2023. Among the female heads of households in the statistical community, 30 women were selected as available and then randomly divided into two groups of 15 including experimental group (training based on mindfulness) and a control group. The research tool included psychological well-being questionnaire (Ryff, 1989). The experimental group was subjected to training based on mindfulness-based therapy (Baer et al., 2006) during 8 90-minute sessions, But the members of the control group did not receive any intervention.
Result
After intervention, there was a significant difference between the components of individual independence, personal development, purposefulness in life, self-acceptance, positive relationship with others, and psychological well-being after the educational intervention between the experimental and control groups (P < 0.05), but no significant difference in Environmental Mastery after the educational intervention between the experimental and control groups (P = 0.602).
Conclusion
According to the results, it seems that psychologists can use the method of training based on mindfulness therapy in order to increase the psychological well-being of women heads of households.
Integrative mRNA and miRNA expression profiles from developing zebrafish head highlight nervous system-preference genes and regulatory networks
Authors: Zhang Shuqiang , Yang Jian , Xu Jie , Li Jing , Xu Lian , Jin Nana , Li Xiaoyu 
Published: October 2023

Abstract
Zebrafish is an emerging animal model for studying molecular mechanism underlying neurodevelopmental disorder due to its advantage characters. miRNAs are small non-coding RNAs that play a key role in brain development. Understanding of dynamic transcriptional and post-transcriptional molecules and their regulation during the head development is important for preventing the neurodevelopmental disorder. In this study, we performed the high-throughput sequencing of mRNAs and miRNAs in developing zebrafish head from pharyngula to early larval stages and carried out bioinformatic analysis including differential expression and functional enrichment as well as joint analysis of miRNAs and mRNAs, and also compared with other related public sequencing datasets to aid our interpretation. A large number of differential expression genes with a large fold-change were detected during the head development. Further clustering and functional enrichment analyses indicated that genes in late stage were most related with synaptic signaling. Overlap test analysis showed a significant enrichment of brain-preference and synapse-associated gene-set in the head transcriptome compared with the whole embryo transcriptome. We also constructed miRNA-mRNAs network for those brain-preference genes and focused on those densely connected network components. Altogether, the present study provides developmental profiles of head-enriched mRNAs and miRNAs at three critical windows for nervous system development, which may contribute to the study of neurodevelopmental disorder.
Pancreatic Cancer Patients’ Readiness for Hospital Discharge following the Management of Enhanced Recovery after Surgery in China: A Cross-Sectional Study
Authors: Kehan Chen , Xu Yin 
Published: October 2023

Abstract

Purpose: The aim of the study was to evaluate the status of readiness for hospital discharge of pancreatic cancer patients and analysis the possible influencing factors.
Methods: A total of 127 pancreatic cancer patients were surveyed from a large public hospital in China from September 2021 to February 2022.The demographic and clinical characteristics of the patients were surveyed by a self-designed questionnaire. Three internationally accepted mature scales were used to measure the scores of readiness for hospital discharge (RHD), quality of discharge teaching (QDT) and general self-efficacy (GSE).
Results: The total score of RHD was 144.52±40.59, which was at a moderate level. whether discharge to rehabilitation institution or not, whether carry tube or not had difference between groups. And the total score of RHD was positively associated with the score of QDT (r = 0.62, P<0.001), GSE (r = 0.58, P<0.001). Then multivariate regression analysis found that three factors associated with RHD: QDT, GSE, and carrying tube.
Conclusion: Pancreatic cancer patients’ readiness for hospital discharge was dissatisfactory, and we need to optimize health education, improve their self-efficacy, pay more attention to the patients discharge with tubes.
Adherence to the Mediterranean diet and the risk of stroke in Chilean population: a case-control study
Authors: Caro Patricia , Hoffmeister Lorena , Lavados Pablo 
Published: October 2023

Abstract
Introduction: Different dietary interventions have been implemented to reduce stroke incidence; one is the Mediterranean diet. Ñuble is the region of Chile with the highest stroke incidence rates in the country. The aim was to estimate the association between adherence to the MED diet and stroke incidence in adult patients living in the Ñuble region.
Methods: A case-control hospital-based study was conducted. The cases (n=89) were patients with first ischemic stroke, and controls (n=178) were admitted to the same hospital during the same month the cases were recruited. We selected two controls for one case and paired them for sex and age (+ 5 years). We used the food frequency questionnaire and the MEDAS questionnaire validated and used in the PREDIMED study to assess adherence to a Mediterranean diet pattern. A descriptive analysis of the variables was performed using absolute frequencies and proportions and a conditional logistic regression to determine the association between variables.
Results: 71% of the sample was ≥65 years old and 64% were male. Cases smoked (11.2%), consumed at least one drink per month (41.6%), and had a diagnosis of hypertension (76.4%) more frequently than controls. In the model adjusted for all variables, it is observed that those who are in quartile 2 of adherence (6-7 points) are 42% less likely to have a cerebral infarction compared to those who have a lower score (p<0.005).
Conclusions: Our findings suggest that moderate adherence to a Mediterranean diet, defined by the PREDIMED score and adjustment for other variables, reduces stroke incidence.
Serological investigation and isolation of pathogenic strains of Salmonella abortus equi in 971 horses from different regions of Xinjiang
Authors: Zhanhai Mai , Han Fu , Ronghao Miao , Chong Lu , Xiaosong Zhang , Ziwen Yuan , Peng Ji , Yongli Hua , Chen Wang , Yuhui Ma , Haifeng Deng , Wei Yanming 
Published: October 2023

Abstract
Background: Salmonella enterica subspecies enterica serovar abortus equi (S. abortus equi) is one of the main pathogens that causes abortion in pregnant horses and donkeys, which was highly infectious and greatly restricts the healthy development of the horse industry.
Objectives: In order to investigate the prevalence and biological characteristics of S. abortus equi in different regions and breeds of horses in Xinjiang.
Methods:This study conducted ELISA detection of S. abortus equi antibodies on serum samples of 971 horses collected from three large-scale horse farms and five free-range horse farms in Yili Prefecture and Bayingol Mongolian Autonomous Prefecture of Xinjiang from 2020 to 2023. On this basis, bacterial isolation, culture, identification, and drug sensitivity tests were conducted on 42 samples of aborted foal tissues and 23 mare vaginal swabs.
Results: The results showed that the positive rate of S. abortus equi antibody was as high as 20.91% in 971 horse serum samples. Among them, the positive rate in the Ili region (29.09%) was significantly higher than that in the Bayingole region (11.24%), and the positive rate in mares (22.45%) was higher than that in stallions (14.05%). In terms of horse breeds, the positive rates of self-propagating thoroughbred horses, half-bred horses, Ili horses and Yanqi horses were 43.22%, 28.81%, 14.72% and 11.24% respectively. In addition, S. abortus equi was more susceptible to juvenile and elderly horses, with positive rates of 70.00% and 41.86%, respectively, both of which were significantly higher than young (10.97%) and adult (19.79%) horses. Further, 9 strains of S. abortus equi were obtained through bacterial isolation, culture and identification, which were resistant to five antibiotics (Clarithromycin, Clindamycin, penicillin, Sulfamethoxazole and Rifampicin), and sensitive to 13 antimicrobial agents (Amoxicillin, Ciprofloxacin and Gentamicin, et al.).
Conclusion: There was a high infection rate of S. abortus equi in Ili Prefecture and self-propagating thoroughbred horses, and juvenile or old mares were more susceptible, which will provide scientific basis for the prevention of S. abortus equiinfection in different regions and breeds of horses in Xinjiang.
Does Fiscal Spending Affect TFP? Evidence from Chinese Provinces
Authors: HE YING , Li Zhan , Xu Zitong 
Published: October 2023

Abstract
This paper utilizes the Bartik instrument to examine the impact of provincial government spending on TFP growth in China. Our analysis reveals a noteworthy relationship: a 1% increase in provincial government spending variable over 2-year horizon would on average lead to a 0.85% increase in TFP growth during 2001–2009 and a 0.25% decrease during 2010–2018. This disparity can be attributed to the varying effects of fiscal spending on above-scale industrial enterprises, which are influenced by change in access to production factors and market power.
JEL codes: H7, E6, O4, L1
Population pharmacokinetics of lenalidomide in Chinese patients with influence of genetic polymorphisms of ABCB1
Authors: Liang Xiaoxiao , Shi Haiyan , Bi Kehong , Feng Saran , Chen Shixian , Zhao Wei , Huang Xin 
Published: October 2023

Abstract
Objective
Affected by differences in the pharmacokinetics (PK) of lenalidomide, the toxicity of lenalidomide varies among different patients, with severe toxicity leading to dose reduction or discontinuation. The differences in the PK of lenalidomide may be related to factors such as patients’ physiological characteristics, pathological characteristics and gene polymorphisms et al., which may also affect its toxicity. The aim of this study is to establish a population pharmacokinetic (PPK) model of lenalidomide and explore factors associated with the adverse events (AEs) of lenalidomide from a PK perspective.
Methods
Blood samples were collected by opportunistic blood collection. Drug concentrations were determined by using HPLC/MS and genotype was tested by the first-generation DNA sequencing technology. NONMEM software and SPSS 26.0 software were used respectively to establish PPK model of lenalidomide and explore the correlation between PK parameters and the incidence of severe AEs of lenalidomide.
Results
A one-compartment model with first-order absorption and elimination agreed well with the observed data. The significant covariate affecting lenalidomide apparent volume of distribution (V/F) were the gene polymorphism of ABCB1 3435 C＞T and diet. The V/F value in patients suffering from severe AEs was significantly higher than that in others ( median = 67.04 L vs 37.17 L, P = 0.033). According to the covariates screened, the incidence of severe AEs was higher in patients with genotype CT or TT at ABCB1 3435 C > T locus than that in patients with genotype CC (P = 0.039). Additionally, V/F value was the highest in patients carrying genotype TT with postprandial medication, in whom the incidence of severe AEs was higher than others (P = 0.037).
Conclusion
The covariates screened were the genotype of ABCB1 3435 C > T locus and diet, which may be related to the incidence of severe AEs. Patients with gene mutations of CT or TT at ABCB1 3435 C > T locus may be more susceptible to severe AEs, and monitoring of adverse reactions should be particularly strengthened in patients who carried genotype TT with postprandial medication.
CAD mutation-associated developmental and epileptic encephalopathy-50 with dramatic response to uridine therapy: A case report and a review of the literature
Authors: Duan Lifen , Ye Lei , Yin Runxiu , Sun Ying , Yu Wei , Zhang Yi , Zhong Haiyan , Bao Xinhua , Tian Xin 
Published: October 2023

Abstract
Background: Developmental and epileptic encephalopathy-50 (DEE-50) is a rare clinical condition believed to be caused by a mutation in the CAD gene and is associated with a bleak prognosis. CAD-related diseases have a wide range of clinical manifestations and other symptoms that may be easily overlooked. Like other rare diseases, the clinical manifestations and therapeutic effects of DEE-50 necessitate further investigation.
Case Presentation: A 1-year-old male patient presented with developmental delay, seizures, and anaemia at 3 months of age. He further developed refractory status epilepticus (SE), rapid deterioration of cognitive and motor function, and even became comatose at 5 months of age. Whole-exome sequencing of trios (WES-trios) revealed a compound heterozygous variant in the CAD gene, with one locus inherited from the father (c.1252C>T: p.Q418* nonsense mutation) and one from the mother (c.6628G>A: p.G2210S, missense mutation). After uridine treatment, his cognitive faculties dramatically improved and he remained seizure-free. We reviewed 42 reported cases of CAD variants, 90% of which had onset before 3 years of age, with a mean age of onset of approximately 1.6±1.8 years, and the age at diagnosis was 6 years. The mortality rate was approximately 9.5%, with all reported deaths occurring in patients who received no uridine treatment. This clinical entity can be effectively treated with uridine.
Conclusions: We present a case of CAD-associated DEE-50, touch upon the details of clinical manifestations and expand the spectrum of CAD mutations. At 5 months of age, he experienced refractory status epilepticus, rapid cognitive and motor function deterioration, and ultimately fell into a comatose state. Early uridine treatment is recommended if a CAD defect is suspected or genetically diagnosed.
Remotely Sensed Top-Down Derived Daily BC Over Rapidly Changing Western China shows Significant Decreases in Mass Due to Policy Action, Coupled with Inconsistent Changes in Number, Size, and Mixing Properties
Authors: Liu Zhewen , Cohen Jason Blake , Wang Shuo , Wang Xinying , Tiwari Pravash , Qin Kai 
Published: October 2023

Abstract

Rapid economic and energy growth in Asia has led to change in the loadings of black carbon (BC) the last two decades. This work uses remotely sensed column aerosol absorption (AAOD) to quantify BC loading day-by-day and grid-to-grid. An unbiased set of observations of remotely sensed NOx and variance maximization uniquely quantify the spatial and temporal boundaries of urban, suburban, and rural sources, including those most rapidly increasing energy source regions. An inversely applied probabilistic MIE algorithm constrains the size, mixing state, and number of BC using four spectral observations. Significant differences in the particle size and mixing state are identified and attributed including: a drop around 2012 when China’s national air pollution policies were adopted, a drop ahead of the 2008 Olympics, and flattening from 2015 onward. A case of simultaneous reduction in BC mass and increase in BC number demonstrate PM2.5 controls may not fully control BC.
Epidural analgesia use during labour in maternity hospitals across China: A prospective case-control questinnaire survey
Authors: Zheng Dequan , Tao Qiang , Shen Ying , Li Yanfei , Yan Ping , An Xiaohu , Xu Tao 
Published: October 2023

Abstract
Background
Specialised maternity hospitals respond to over 90% of labour analgesia requests in their localities within China. We administered a questionnaire survey to determine the predictors of labour analgesia use in two of these hospitals, with the aim of further enhancing epidural analgesia utilisation during labour.
Methods
This prospective case-control multi-centre questionnaire survey included a total of 640 postpartum women with 374 women who received epidural analgesia and 266 women who did not receive epidural analgesia. The questionnaire contained 20 questions and was distributed through WeChat from July 2022 to September 2022. The responses to the questionnaires were uploaded to the cloud storage space, and only the statistician had access to the original data. Multivariate logistic regression analysis was used to screen variables related to the receipt of epidural labour analgesia. Binary logistic regression was used to identify predictors related to the administration of epidural labour analgesia from a set of selected variables.
Results
Binary logistic regression results of the survey data showed that multi-parity (odds ratio [OR] 2.805, 95% confidence interval [CI] 1.792 to 4.393, P < 0.001), late arrival of anaesthesiologist (OR 2.728, 95% CI 1.180–6.306, P = 0.019), and rapid progress in first stage of labour (OR 11.709, 95% CI 7.449–18.404, P < 0.001) prevented women from receiving epidural labour analgesia, while women’s preference (OR 0.035, 95% CI 0.013–0.097, P < 0.001) and family agreement to epidural analgesia prior to labour (OR 0.091, 95% CI 0.016–0.551, P = 0.006) promoted its use.
Conclusions
To address the factors that may hinder or promote the use of epidural labour analgesia in maternal specialised hospitals, pregnant women should be screened for the risk of rapid progression in the first stage of labour and be provided latent-phase labour analgesia. Moreover, in cases where anaesthesiologists are unavailable or when women have contraindications to epidural analgesia, inhalation nitrous oxide analgesia and intravenous remifentanil analgesia should be considered as alternative options. It is recommended that hospitals provide professional, comprehensive, and free antenatal education on labour analgesia to pregnant women and their families to further promote the use of epidural analgesia.
Trial registration:
http://www.chictr.org.cn ChiCTR2200055621; January 15, 2022.