bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultralight Membrane Structures Toward a Sustainable Environment
Authors: Comitti Alessandro , Vijayakumaran Harikrishnan , Nejabatmeimandi Mohammad Hosein , Seixas Luis , Cabello Adrian , Misseroni Diego , Penasa Massimo , Paech Christoph , Bessa Miguel , Bown Adam C. , Dal Corso Francesco , Bosi Federico 
Published: January 2024

AbstractThe building construction industry is the largest anthropogenic source of pollution, with massive energy consumption and substantial CO2 emissions. Lightweight tension structures allow the simultaneous implementation of several sustainable strategies by using recyclable low-carbon structural membranes offering a greener alternative to glass and other cladding materials. Their efficient structural load-bearing mechanisms result in significant weight savings in buildings and a drastic reduction of the environmental impact associated with material production, transportation, use, and disposal. A subgroup of lightweight materials, structural fabrics, and foils has been gaining popularity among designers and architects in recent years because of their desirable features such as high stiffness, strength, ductility, durability, and functional properties. While these structural membranes open new crucial perspectives for the clean energy transition and have been recently employed worldwide, their full potential is still limited by the lack of construction codes, advanced optimization tools, and comprehensive viscous-thermo-mechanical constitutive models. This chapter aims to foster the design of membrane structures by presenting their basic principles and recent advancements in the field. It covers the design approaches, employed materials and efforts in their characterization and modeling, implications on the sustainability of the built environment, current challenges, and future pathways from both academic research and engineering design viewpoints.
Anomaly-free dark matter models with one-loop neutrino masses and a gauged U(1) symmetry
Authors: de Boer T. , Klasen M. , Zeinstra S. 
Published: January 2024

Abstract
We systematically study and classify scotogenic models with a local U(1) gauge symmetry. These models give rise to radiative neutrino masses and a stable dark matter candidate, but avoid the theoretical problems of global and discrete symmetries. We restrict the dark sector particle content to up to four scalar or fermionic SU(2) singlets, doublets or triplets and use theoretical arguments based on anomaly freedom, Lorentz and gauge symmetry to find all possible charge assignments of these particles. The U(1) symmetry can be broken by a new Higgs boson to a residual discrete symmetry, that still stabilizes the dark matter candidate. We list the particle content and charge assignments of all non-equivalent models. Specific examples in our class of models that have been studied previously in the literature are the U(1)D scotogenic and singlet-triplet scalar models breaking to Z2. We also briefly discuss the new phenomenological aspects of our model arising from the presence of a new massless dark photon or massive Z′ boson as well as the additional Higgs boson.
Quercetin: a promising virulence inhibitor of Pseudomonas aeruginosa LasB in vitro
Authors: Ren Yanying , Zhu Rui , You Xiaojuan , Li Dengzhou , Guo Mengyu , Fei Bing , Liu Ying , Yang Ximing , Liu Xinwei , Li Yongwei 
Published: January 2024

Abstract
With the inappropriate use of antibiotics, antibiotic resistance has emerged as a major dilemma for patients infected with Pseudomonas aeruginosa. Elastase B (LasB), a crucial extracellular virulence factor secreted by P. aeruginosa, has been identified as a key target for antivirulence therapy. Quercetin, a natural flavonoid, exhibits promising potential as an antivirulence agent. We aim to evaluate the impact of quercetin on P. aeruginosa LasB and elucidate the underlying mechanism. Molecular docking and molecular dynamics simulation revealed a rather favorable intermolecular interaction between quercetin and LasB. At the sub-MICs of ≤256 μg/ml, quercetin was found to effectively inhibit the production and activity of LasB elastase, as well as downregulate the transcription level of the lasB gene in both PAO1 and clinical strains of P. aeruginosa. Through correlation analysis, significant positive correlations were shown between the virulence gene lasB and the QS system regulatory genes lasI, lasR, rhlI, and rhlR in clinical strains of P. aeruginosa. Then, we found the lasB gene expression and LasB activity were significantly deficient in PAO1 ΔlasI and ΔlasIΔrhlI mutants. In addition, quercetin significantly downregulated the expression levels of regulated genes lasI, lasR, rhlI, rhlR, pqsA, and pqsR as well as effectively attenuated the synthesis of signaling molecules 3-oxo-C12-HSL and C4-HSL in the QS system of PAO1. Quercetin was also able to compete with the natural ligands OdDHL, BHL, and PQS for binding to the receptor proteins LasR, RhlR, and PqsR, respectively, resulting in the formation of more stabilized complexes. Taken together, quercetin exhibits enormous potential in combating LasB production and activity by disrupting the QS system of P. aeruginosa in vitro, thereby offering an alternative approach for the antivirulence therapy of P. aeruginosa infections.

Key points
• Quercetin diminished the content and activity of LasB elastase of P. aeruginosa.
• Quercetin inhibited the QS system activity of P. aeruginosa.
• Quercetin acted on LasB based on the QS system.
Older adults’ communication with an interactive humanoid robot
Authors: Strutz Nicole , Perotti Luis , Heimann-Steinert Anika , Klebbe Robert 
Published: January 2024

Abstract
Background and objective
One possible approach to counter singularization and loneliness of older adults is the development and implementation of socially interactive robots. Little is known about the expectations and experiences of older adults with socially interactive humanoid robots.

Material and methods
In a mixed-methods design study, user expectations before interaction and the experience and evaluation of verbal and non-verbal communication after interaction with a robot were assessed. Semi-structured interviews were conducted after the interaction.

Results
The majority of older adults expected verbal communication. After the interaction the evaluation of the quality of verbal communication differed. Participants did not expect any form of nonverbal communication. Nonverbal communication was highlighted as particularly positive. Gestures, facial expressions, and body movements were described as confidence building.

Conclusion
The robot’s ability to communicate nonverbally might positively influence older adults’ experience of communication with the robot. In the development of socially interactive robots non-verbal communication should be given more consideration in order to contribute to successful human-robot interaction.
Optimizing vestibular implant electrode positioning using fluoroscopy and intraoperative CT imaging
Authors: Loos Elke , Stultiens Joost J. A. , Volpe Benjamin , Vermorken Bernd L. , Van Boxel Stan C. J. , Devocht Elke M. J. , van Hoof Marc , Postma Alinda A. , Guinand Nils , Pérez-Fornos Angelica , Van Rompaey Vincent , Denys Sam , Desloovere Christian , Verhaert Nicolas , van de Berg Raymond 
Published: January 2024

Abstract
Purpose
Vestibular implant electrode positioning close to the afferent nerve fibers is considered to be key for effective and selective electrical stimulation. However, accurate positioning of vestibular implant electrodes inside the semicircular canal ampullae is challenging due to the inability to visualize the target during the surgical procedure. This study investigates the accuracy of a new surgical protocol with real-time fluoroscopy and intraoperative CT imaging, which facilitates electrode positioning during vestibular implant surgery.

Methods
Single-center case-controlled cohort study with a historic control group at a tertiary referral center. Patients were implanted with a vestibulocochlear implant, using a combination of intraoperative fluoroscopy and cone beam CT imaging. The control group consisted of five patients who were previously implanted with the former implant prototype, without the use of intraoperative imaging. Electrode positioning was analyzed postoperatively with a high-resolution CT scan using 3D slicer software. The result was defined as accurate if the electrode position was within 1.5 mm of the center of the ampulla.

Results
With the new imaging protocol, all electrodes could be positioned within a 1.5 mm range of the center of the ampulla. The accuracy was significantly higher in the study group with intraoperative imaging (21/21 electrodes) compared to the control group without intraoperative imaging (10/15 electrodes), (p = 0.008).

Conclusion
The combined use of intraoperative fluoroscopy and CT imaging during vestibular implantation can improve the accuracy of electrode positioning. This might lead to better vestibular implant performance.
Superconcentration for minimal surfaces in first passage percolation and disordered Ising ferromagnets
Authors: Dembin Barbara , Garban Christophe 
Published: January 2024

AbstractWe consider the standard first passage percolation model on $${\mathbb {Z}}^ d$$

Z

d

with a distribution G taking two values $$0<a<b$$

0
<
a
<
b

. We study the maximal flow through the cylinder $$[0,n]^ {d-1}\times [0,hn]$$

[
0
,
n
]

d
-
1

×

[
0
,
h
n
]

between its top and bottom as well as its associated minimal surface(s). We prove that the variance of the maximal flow is superconcentrated, i.e. in $$O(\frac{n^{d-1}}{\log n})$$

O
(

n

d
-
1

log
n

)

, for $$h\ge h_0$$

h
≥

h
0

(for a large enough constant $$h_0=h_0(a,b)$$

h
0

=

h
0

(
a
,
b
)

). Equivalently, we obtain that the ground state energy of a disordered Ising ferromagnet in a cylinder $$[0,n]^ {d-1}\times [0,hn]$$

[
0
,
n
]

d
-
1

×

[
0
,
h
n
]

is superconcentrated when opposite boundary conditions are applied at the top and bottom faces and for a large enough constant $$h\ge h_0$$

h
≥

h
0

(which depends on the law of the coupling constants). Our proof is inspired by the proof of Benjamini–Kalai–Schramm (Ann Probab 31:1970–1978, 2003). Yet, one major difficulty in this setting is to control the influence of the edges since the averaging trick used in Benjamini et al. (Ann Probab 31:1970–1978, 2003) fails for surfaces. Of independent interest, we prove that minimal surfaces (in the present discrete setting) cannot have long thin chimneys.
VolcAshDB: a Volcanic Ash DataBase of classified particle images and features
Authors: Benet Damià , Costa Fidel , Widiwijayanti Christina , Pallister John , Pedreros Gabriela , Allard Patrick , Humaida Hanik , Aoki Yosuke , Maeno Fukashi 
Published: January 2024

AbstractVolcanic ash provides unique pieces of information that can help to understand the progress of volcanic activity at the early stages of unrest, and possible transitions towards different eruptive styles. Ash contains different types of particles that are indicative of eruptive styles and magma ascent processes. However, classifying ash particles into its main components is not straightforward. Diagnostic observations vary depending on the magma composition and the style of eruption, which leads to ambiguities in assigning a given particle to a given class. Moreover, there is no standardized methodology for particle classification, and thus different observers may infer different interpretations. To improve this situation, we created the web-based platform Volcanic Ash DataBase (VolcAshDB). The database contains > 6,300 multi-focused high-resolution images of ash particles as seen under the binocular microscope from a wide range of magma compositions and types of volcanic activity. For each particle image, we quantitatively extracted 33 features of shape, texture, and color, and petrographically classified each particle into one of the four main categories: free crystal, altered material, lithic, and juvenile. VolcAshDB (https://volcash.wovodat.org) is publicly available and enables users to browse, obtain visual summaries, and download the images with their corresponding labels. The classified images could be used for comparative studies and to train Machine Learning models to automatically classify particles and minimize observer biases.
Partizipation im innerstädtischen Transformationsprozess: Das Beispiel der „Zukunftswerkstatt Innenstadt“ in Peine
Authors: Förster Amelie , Panzer-Krause Sabine 
Published: January 2024

ZusammenfassungMit dem Sofortprogramm „Perspektive Innenstadt“, das von 2021–2023 lief, wurden Kommunen in Niedersachsen bei der Bewältigung der Folgen der COVID-19-Pandemie in den Innenstädten unterstützt. Gleichzeitig fördert auch das Bundesprogramm „Zukunftsfähige Innenstädte und Zentren“ bis 2025 die Umsetzung innovativer Konzepte und Handlungsstrategien zur Stärkung der Resilienz der Innenstädte. Im Rahmen eines Beteiligungsprozesses haben sich die städtischen Akteure im niedersächsischen Mittelzentrum Peine über Maßnahmen für beide Programme verständigt. Diese Studie untersucht den partizipativen Prozess mit Blick auf die beteiligten Akteure, um Erfolgsfaktoren und Hindernisse städtischer Beteiligungsprozesse zu identifizieren. Dazu wurden eine nichtteilnehmende Beobachtung sowie Expert*inneninterviews durchgeführt. Die Untersuchung zeigt, dass sich neben der Innenstadt und dem Einzelhandel auch Peines Akteursgefüge der Stadtentwicklung in einer Transformationsphase befindet, welche vor allem durch die Etablierung eines integrierten Stadtmarketings Potenzial für eine erfolgreiche Neupositionierung der Innenstadt bietet. Zudem wird aber auch deutlich, dass sich Politik und Verwaltung noch stärker neuen Beteiligungsformen gegenüber öffnen und den Ausbau einer engen und langfristigen Kooperation aller städtischen, Akteure weiter vorantreiben müssen.
Dental and periodontal dimensions stability after esthetic clinical crown lengthening surgery: a 12‐month clinical study
Authors: Carneiro Valéria Martins de Araújo , Gomes Andressa Meireles Seabra , Marinho Mônica Umpierre , de Melo Gabriel Simino , Kasabji Feras , An Tien-Li , Stefani Cristine Miron , Guimarães Maria do Carmo Machado , Andrade Carlos Alexandre Soares 
Published: January 2024

Abstract
Objectives
To evaluate the stability of periodontal tissues 3 (T3), 6 (T6), and 12 (T12) months after esthetic crown lengthening (ACL) and the possible correlations between changes in those structures.

Materials and methods
Twenty individuals were evaluated through clinical assessment, photography, and tomography. Measurements included gingival margin (GM), clinical crown length (CCL), interdental papilla height (PH) and width (PW), gingival thickness (GT), bone thickness (BT), probing depth (PD), distance between alveolar crest and GM, distance between alveolar crest and cementoenamel junction. Nonparametric and correlation statistics were performed (p < 0.05).

Results
CCL at T0 was 7.42 ± 0.70 mm and increased to 9.48 ± 0.49 mm immediately after ACL, but it decreased to 8.93 ± 0.65 mm at T12. PD decreased 0.60 mm from T0 to T6, and it increased 0.39 mm from T6 to T12. BT decreased 0.20 mm, while GT increased 0.29 mm from T0 to T12. Both PW and PH showed enlargement in T12. A positive moderate correlation was found between CCL/T0 and CCL/T12, GT/T0 and AC-GM/T12, BT/T0 and GT/T12. A few negative moderate correlations were PD/T0 and CCL/T12, PD/T0 and PH/T0, PD/T0 and BT/T12.

Conclusions
ACL procedure was effective. Although some rebound occurred, that was not clinically important. PD tended to reestablish its original length, partially due to a migration of GM during the healing period. Besides, a thickening of supracrestal soft tissues was observed.

Clinical relevance
The present study centers on the factors influencing the stability of periodontal tissues after esthetic crown lengthening, underscoring the procedure’s influence on esthetics and biology and the need for careful treatment planning.
Impact of COVID-19 pandemic on prescription stimulant use among children and youth: a population-based study
Authors: Antoniou Tony , Pajer Kathleen , Gardner William , Penner Melanie , Lunsky Yona , McCormack Daniel , Tadrous Mina , Mamdani Muhammad , Gozdyra Peter , Juurlink David N. , Gomes Tara 
Published: January 2024

AbstractCOVID-19 associated public health measures and school closures exacerbated symptoms in some children and youth with attention-deficit hyperactivity disorder (ADHD). Less well understood is how the pandemic influenced patterns of prescription stimulant use. We conducted a population-based study of stimulant dispensing to children and youth ≤ 24 years old between January 1, 2013, and June 30, 2022. We used structural break analyses to identify the pandemic month(s) when changes in the dispensing of stimulants occurred. We used interrupted time series models to quantify changes in dispensing following the structural break and compare observed and expected stimulant use. Our main outcome was the change in the monthly rate of stimulant use per 100,000 children and youth. Following an initial immediate decline of 60.1 individuals per 100,000 (95% confidence interval [CI] − 99.0 to − 21.2), the monthly rate of stimulant dispensing increased by 11.8 individuals per 100,000 (95% CI 10.0–13.6), with the greatest increases in trend observed among females, individuals in the highest income neighbourhoods, and those aged 20 to 24. Observed rates were between 3.9% (95% CI 1.7–6.2%) and 36.9% (95% CI 34.3–39.5%) higher than predicted among females from June 2020 onward and between 7.1% (95% CI 4.2–10.0%) and 50.7% (95% CI 47.0–54.4%) higher than expected among individuals aged 20–24 from May 2020 onward. Additional research is needed to ascertain the appropriateness of stimulant use and to develop strategies supporting children and youth with ADHD during future periods of long-term stressors.
Correlation of visual field deficits and q-ball high-resolution fiber tractography of the optic radiation for adjacently located intracerebral lesions: preliminary results from a single-center prospective study
Authors: Lenga Pavlina , Scherer Moritz , Peretzke Robin , Neher Peter , Jesser Jessica , Beisse Christina , Unterberg Andreas W. , Daniela Becker 
Published: January 2024

AbstractVisual field deficits (VFDs) are common in patients with temporal and occipital lobe lesions. Diffusion tensor fiber tractography (DTI-FT) is widely used for surgery planning to reduce VFDs. Q-ball high-resolution fiber tractography (QBI-HRFT) improves upon DTI. This study aims to evaluate the effectiveness of DTI-FT and QBI-HRFT for surgery planning near the optic radiation (OR) as well as the correlation between VFDs, the nearest distance from the lesion to the OR fiber bundle (nD-LOR), and the lesion volume (LV). This ongoing prospective clinical trial collects clinical and imaging data of patients with lesions in deterrent areas. The present subanalysis included eight patients with gliomas near the OR. Probabilistic HRFT based on QBI-FT and conventional DTI-FT were performed for OR reconstruction based on a standard diffusion-weighted magnetic resonance imaging sequence in clinical use. Quantitative analysis was used to evaluate the lesion volume (LV) and nD-LOR. VFDs were determined based on standardized automated perimetry. We included eight patients (mean age 51.7 years [standard deviation (SD) 9.5]) with lesions near the OR. Among them, five, two, and one patients had temporodorsal, occipital, and temporal lesions, respectively. Four patients had normal vision preoperatively, while four patients had preexisting VFD. QBI-FT analysis indicated that patients with VFD exhibited a significantly smaller median nD-LOR (mean, −4.5; range −7.0; −2.3) than patients without VFD (mean, 7.4; range −4.3; 27.2) (p = 0.050). There was a trend towards a correlation between tumor volume and nD-LOR when QBI-FT was used (rs = −0.6; p = 0.056). A meticulous classification of the spatial relationship between the lesions and OR according to DTI-FT and QBI-FT was performed. The results indicated that the most prevalent orientations were the FT bundles located laterally and intrinsically in relation to the tumor. Compared with conventional DTI-FT, QBI-FT suggests reliable and more accurate results when correlated to preoperative VFDs and might be preferred for preoperative planning and intraoperative use of nearby lesions, particularly for those with larger volumes. A detailed analysis of localization, surgical approach together with QBI-FT and DTI-FT could reduce postoperative morbidity regarding VFDs. The display of HRFT techniques intraoperatively within the navigation system should be pursued for this issue.
Clinical outcomes of sentinel node navigation surgery in patients with preoperatively estimated stage IA endometrial cancer and evaluation of validity for continuing sentinel node navigation surgery based on dispersion of recurrence probability
Authors: Yamashita Tsuyoshi , Itoh Takahiro , Asano Takuya , Suina Asuka , Nishimori Mitsutaka , Munakata Satoru , Satoh Hideki 
Published: January 2024

Abstract
Background
To evaluate the feasibility of the use and continuation of sentinel lymph node navigation surgery (SNNS) as an alternative to pelvic lymph node dissection (PLND) for patients with preoperatively estimated stage IA endometrial cancer.

Methods
This retrospective study selected the electronic medical records of all patients who had received CT scans and MRI imaging before surgery from April 1, 2009 to March 31, 2021. Sentinel lymph nodes (SLNs) were detected by administrating 99mTc-phytate and/or indocyanine green into the cervix, and the clinical outcomes of the patients who underwent SNNS or PLND were evaluated. Furthermore, in case of nodal recurrence, a new procedure to determine whether the facility should continue with SNNS or not was developed that compares the maximum likelihood hypothesis and an alternative one based on recurrence rates.

Results
Among 137 patients, SLN biopsies with ultrastaging were performed on 91 patients. The SLN detection rate was 95.6%. Over a 59-month median observation period, no statistically significant differences were shown in overall survival, disease-specific survival and disease-free survival between the SNNS and PLND groups when introducing the propensity score method (p-values: 0.06, 0.153, and 0.625, respectively). Our procedure demonstrated that, in our department without recurrence up to the 65th attempt, it was possible to continue SNNS if a recurrence occurs at the 66th attempt.

Conclusion
This study suggests the validity of SNNS as an alternative to PLND. Even in the absence of evidence from randomized controlled trials, we can confirm the validity of continuing SNNS using our procedure.