bluuebunny/crossref_metadata_2025_split huggingface dataset:
PEMBUATAN VIDEO TUTORIAL TEKNIK WINGED EYELINER PADA TATA RIAS WAJAH KOREKTIF UNTUK MATA BULAT
Authors: Titin Supiani  , Salsa Salsabila Ramadhanti 
Published: October 2023

Pembuatan video tutorial ini bertujuan untuk mengetahui kelayakan video tutorial teknik winged eyeliner pada tata rias wajah korektif untuk mata bulat sebagai alternatif sumber belajar dalam bidang kecantikan khususnya dalam merias wajah. Dalam proses produksi video menggunakan standar operasional prosedur yang dibagi menjadi 3 Tahapan yaitu Tahap Pra Produksi, Tahap Produksi, dan Tahap Pasca produksi. Dimana penelitian ini dilakukan kepada model yang memiliki bentuk mata bulat. Metode yang digunakan pada penelitian ini yaitu metode pengembangan dengan penilaian video oleh 2 orang ahli yaitu Ahli Materi dan Ahli Media utuk menguji kelayakan video tutorial. Berdasarkan uji kelayakan, didapatkan hasil uji kelayakan Ahli Materi sebesar 90% pada kategori penilaian materi sangat layak dan Ahli Media sebesar 92% pada kategori penilaian media sangat layak. Berdasarkan hasil tersebut maka video tutorial dinyatakan sangat layak digunakan sebagai alternatif sumber belajar dalam bidang kecantikan khususnya dalam merias wajah.
Kata Kunci: Video Tutorial, Teknik Winged Eyeliner, Rias Korektif Mata
Pengembangan Video Tutorial Teknik Jahit Bulu Mata Pada Tata Rias Pengantin India
Authors: Nazla Alinkaputri Tresna  , Sri Irtawidjajanti  
Published: October 2023

Abstrak
Pembuatan video tutorial jahit bulumata pada pengantin India adalah video yang berisikan mengenai riasan wajah pengantin India dan teknik jahit bulumata. Penelitian ini bertujuan untuk membuat produk berupa video tutroial yang layak. Proses didalam pembuatan video ini terdiri dari proses perencanaan,produksi dan setelah produksi. Tata rias pengantin India memiliki tampilan riasan wajah yang menghasilkan riasan wajah bold. Memiliki ciri khas pada alis dan riasan mata yang membuat mata terlihat lebih tajam. Teknik Jahit bulumata membuat mata kita terkesan lebih terbuka dan membuat mata lebih bulat.Penelitian ini merupakan penelitian dan pengembangan (R & D). Hasil pembuatan video ini memenuhi kriteria validasi dengan hasil yang di dapat oleh ahli materii 80%, oleh ahli media 100%.. Yang dapat disimpulkan bahwa video tersebut layak untuk digunakan sebagai media alternatif serta mempermudah untuk mendapatkan informasi dan pengetahuan terkait video tutorial jahit bulumata pada pengantin India.
Diversity Within the Field of Orthopedic Sports Medicine
Authors: Leal Justin , Clifford Alexis L. , Anastasio Albert T. , Dymtruk Michael , Roach Ryan P. 
Published: October 2023

Background:
Orthopedic surgery is among the least diverse specialties in medicine. This systematic review analyzes gender, racial, and ethnic diversity within orthopedic sports medicine and aims to raise awareness and provide guidance for future strategies that support underrepresented minorities in medicine (URMs) and women in joining the orthopedic sports medicine workforce. We hypothesize that at all tiers of training, there is a lack of gender, racial, and ethnic parity in academic rank, leadership positions, and research productivity.

Methods:
A search of all published literature in the English language from PubMed, Embase, Cochrane, and Scopus databases, between January 1, 2010, and August 18, 2023, was performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Included studies presented demographics regarding diversity within orthopedic sports medicine and provided trends in applicants, attendings, leadership, and/or research. Bias was assessed using the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) study checklist.

Results:
Thirteen studies published between 2016 and 2023 with STROBE scores 15.5 to 21.5 (70.5% to 97.7%) met criteria, and pertinent data were extracted. The percent of female orthopedic sports medicine surgeons from 2010 to 2019 increased from 5% (n = 138) to 6% (n = 206) with a compound annual growth rate of 0.2% (r2 = 0.97; p < 0.001). Females and URMs are underrepresented at the highest levels of orthopedic sports medicine leadership including department chair (female: 0% [n = 0]), division chief (female: 4% [n = 4]; URM: 3% [n = 3]), and fellowship director (female: 3.3% [n = 3]; URM: 4.4% [n = 4]). Studies from prominent orthopedic sports medicine journals (American Journal of Sports Medicine, Arthroscopy, Journal of Shoulder and Elbow Surgery, and Sports Health) show a 12.1% increase in female involvement in orthopedic sports medicine research from 1972 to 2018; however, this increase captures 59.3% (n = 2,953) females with degrees other than an MD.

Conclusions:
Although increasingly more females and underrepresented minorities are joining orthopedic sports medicine, the rate of diversification remains slow and current involvement in leadership and research is minimal. Targeted efforts aimed at increasing research opportunities and inspiring interest through mentorship for URMs and females in orthopedics is essential to drive change toward parity.

Level of Evidence:

Level IV. Systematic Review. See Instructions for Authors for a complete description of levels of evidence.
Phytotoxic study of glycosylated flavonols from Annona coriacea (Annonaceae) on cultivated species and an invasive grass.
Authors: Novaes Paula , Lopes Jenifer de Carvalho , Ferreira Marcelo J Pena , Santos Déborah Yara Alves Cursino 
Published: October 2023

Abstract
Annona coriacea Mart. is a Brazilian native species whose phytotoxicity was described, although there is no data about the compounds responsible for it. The aim of this study was bioprospecting A. coriacea in relation to phytotoxicity on the elongation of wheat elongation coleoptiles and on germination and initial growth of standard target species (lettuce and tomato) and a weed (Urochloa decumbens (Stapf) R.D. Webster). Thus, the leaf ethanolic extract was subjected to chromatographic separation furnishing the isolation of 11 flavonols: 1 - Quercetin-3-O-gentiobioside, 2 - Quercetin-3-O-robinobioside, 3 - Rutin, 4 - Hyperin, 5 - Isoquercitrin, 6 - Biorobin, 7 - Nicotiflorin, 8 -Keioside, 9 - Narcissin, 10 - Cacticin and 11 - Isorhamnetin-3-O-glucoside. This is the first report of wheat coleoptile bioassay to all these compounds and it is also the first phytotoxicity results for 1, 2, 6, 8 and 10. Compounds 5, 7 and 11 showed elevated phytotoxicity in wheat coleoptiles bioassay (IC50 0.22 mM, r2 0.97; IC50 0.48 mM, r2 0.93; IC50 0.28 mM, r2 0.92, respectively). No correlation was found between the structure of the compounds and their activity. Compounds 5 and 11 were also tested on diaspores. Compound 11 significantly reduced the germination of U. decumbens in almost all concentrations, with values between 50% and 65%. The broad distinction concerning the complexity of the biological systems was suggested as an explanation for the distinct effects observed for coleoptile and germination and initial growth assays.
Generation of a lethal mouse model expressing human ACE2 and TMPRSS2 for SARS-CoV-2 infection and pathogenesis
Authors: Kim Kyun Do , Jeong Gi Uk , Hwang Insu , Lee Wooseong , Choi Ji Hyun , Young Yoon Gun , Kim Hae Soo , Yang Jeong-Sun , Kim Kyung-Chang , Lee Joo-Yeon , Kim Seong-Jun , Kwon Young-Chan 
Published: October 2023

Abstract

Mouse models expressing human ACE2 for coronavirus disease 2019 have been frequently used to understand its pathogenesis and develop therapeutic strategies against SARS-CoV-2. Given that human TMPRSS2 supports viral entry, replication, and pathogenesis, we established a double-transgenic mouse model expressing both human ACE2 and TMPRSS2 for SARS-CoV-2 infection. Co-overexpression of both genes increased viral infectivity in vitro and in vivo. Notably, double-transgenic mice showed significant body weight loss, clinical disease symptoms, acute lung injury, lung inflammation, and lethality in response to viral infection, indicating that they were highly susceptible to SARS-CoV-2. Pretreatment with the TMPRSS2 inhibitor, nafamostat, effectively reduced virus-induced weight loss, viral replication, and mortality in the double-transgenic mice. Moreover, the susceptibility and differential pathogenesis of SARS-CoV-2 variants were demonstrated in this animal model. Together, our results demonstrate that double-transgenic mice could provide a highly susceptible mouse model for viral infection to understand SARS-CoV-2 pathogenesis and evaluate antiviral therapeutics against coronavirus disease 2019.
Intellectual Property Protection and Synergizing the Reduction of Pollution and Carbon Emissions: Evidence from a Quasi-Natural Experiment
Authors: Xu Jiajun , Wang Jinchao , Yang Xiaojun , Liu Yiming 
Published: October 2023

Abstract
The Chinese government is implementing a Synergizing the Reduction of Pollution and Carbon Emissions (SRPC) strategy to shift to green development. This study aims to assess whether a good intellectual property (IPR) environment is conducive to SRPC in Chinese cities. Based on data from 284 cities in China from 2004–2019, we employ the Driver-Pressure-State-Impact-Response-Management (DPSIRM) model to measure SRPC levels at the city level. We then use China's Intellectual Property Model City (IPMC) pilot policy as a quasi-natural experiment and apply a multi-period difference model to investigate the impact of establishment on urban SRPC. The study finds that the IPMC pilot policy promotes urban SRPC, and the findings hold after rigorous robustness tests. The mechanism is that the IPMC pilot policy promotes green technology innovation (GTI), draws government attention, and optimizes elements allocation. In addition, the heterogeneity test shows that the effect is greater in the Northeast cities as well as in small and medium-sized cities, while the effect is not significant in the West. Our findings provide theoretical and practical insights into how China can enhance IPR protection to advance SRPC.
Biodiversity of Morchella in Switzerland: a study highlighting the diversity of native black morels and the discovery of five new phylogenetic lineages
Authors: Cravero Melissa , Bonito Gregory , Robinson Aaron J. , Chain Patrick S. , Bindschedler Saskia , Junier Pilar 
Published: October 2023

Abstract
True morels (Morchella spp.) are a diverse fungal genus with more than 80 recognized species that show high continental endemism. The cultivation of Asian morel isolates in Europe is becoming more common in Switzerland and other European countries, however, the impact this may have on the diversity of native morel populations remains unknown. In order to address this, we sought to establish an initial inventory of the diversity of native morel species across Switzerland. The biodiversity of morels was assessed through a combination of field collection and multi-locus (ITS, RPB1, RPB2 and TEF1-a markers) phylogenetic analysis. The analyses of a collection of 141 morel fruiting bodies revealed a high diversity within Morchella Sect. Distantes, and the discovery of five new phylogenetic lineages denoted as Morchella sp. Mel-43, Mel-44, Mel-45, Mel-46 and Mel-47. In addition, Morchella importuna, Morchella deliciosa, Morchella pulchella, and Morchella esculenta were detected in Switzerland.
High nanoplastic concentrations across the North Atlantic
Authors: Materic Dusan , Hietbrink Sophie ten , Holzinger Rupert , Niemann Helge 
Published: October 2023

Abstract

Plastic pollution of the marine realm is globally ubiquitous and a substantial body of research has concentrated on microplastics (1 µm – 5 mm). Ocean nanoplastics (<1 µm), in contrast, are understudied and the mass budget of this domain thus remains unknown. Here we measured nanoplastic concentrations on an ocean basin scale along a transect crossing the North Atlantic from the subtropical gyre to the northern European shelf using Thermal Desorption – Proton Transfer Reaction – Mass Spectrometry. Substantial amounts of polystyrene (PS), polyvinyl chloride (PVC) and polyethylene terephthalate (PET) nanoplastic (~2-25 ng ml-1) were observed throughout the entire water column (measured in the well-mixed surface layer, at 1 kilometer depth and in bottom waters). We found higher nanoplastic concentrations in the well-mixed surface layer closer to the European continent, while bottom waters contained the lowest nanoplastic concentrations (primarily comprising PET). A conservative extrapolation of our findings shows that the total (PS+PVC+PET) nanoplastic mass in the well-mixed surface layer of the North Atlantic Ocean alone amounts to 33-50 million tonnes (Mt). This is in the same range or exceeds previous macro/microplastic budgets estimates for the entire Atlantic1 or global Ocean2,3,4. Our findings suggest that nanoplastics are the most important part of ocean plastic pollution.
A local-to-global emissions inventory of macroplastic pollution
Authors: Velis Costas , Cottom Joshua , Cook Ed 
Published: October 2023

Abstract

Negotiations for a Global Treaty on plastic pollution1 will shape policy on plastics production, use, and waste management for the coming decades. Parties will require a detailed baseline of waste flows and plastic emission sources at high resolution to enable identification of pollution hotspots and their causes2. Nationally aggregated waste management data can be distributed to smaller scale to identify generalised points of plastic accumulation and source phenomena3-11. However, it is challenging to use this type of spatial allocation to assess the conditions under which emissions take place12,13. To this, we developed a novel methodology for a global macroplastic waste inventory; creating an explanatory framework that combines conceptual modelling of emission mechanisms with measurable activity data. Using machine learning and probabilistic material flow analysis we identify hotspots worldwide (50,072 municipalities) from five land-based plastic waste emission sources. We estimate global plastic waste emissions at 52.5 million metric tonnes (Mt), of which 57% wt. are open burned. Highest contributions: India (9.7 Mt), Nigeria (3.5 Mt), and Indonesia (3.0 Mt). Uncollected waste is the dominant emissions source across Global South. This detailed evidence baseline can inform Treaty negotiations and help develop national and sub-national waste management action plans and source inventories.
Effect of sewage sludge and digestate from anaerobic fermentation as soil additives on the nutritional status and accumulation of non-essential elements in plants with different nutrition strategies
Authors: Zaffar Nazia , Peiter Edgar , Schirmer Dominic , Samarska Alla , Lovynska Viktoriia , Wiche Oliver 
Published: October 2023

Abstract
We explored how sewage sludge and digestate as a soil amendment impact the availability of non-essential elements to plants with different nutrition strategies. Four species were cultivated on soil or soil amended with sewage sludge and digestate: the specialized Ni hyper-accumulator Alyssum murale, the P-efficient Mn accumulator Lupinus albus, the P-inefficient metal accumulator Fagopyrum esculentum and the excluder species Carthamus tinctorius. Shoot accumulation of essential (P, Mg, Fe, Mn, Zn, Ni) and non-essential elements (As, Cd, Pb, Ge, Ga, rare earth elements: REE) was evaluated together with changes of labile element concentrations in soil. Shoot metal(loid) contents decreased in the order F. esculentum > C. tinctorius, L. albus > A. murale. Both treatments improved micronutrient supply in all species; however, shoot P only increased in sewage sludge-treated plants. Both treatments increased the concentrations of labile As, Ge, Ga and REE in soil, while labile Cd was exclusively higher when sewage sludge was added. The digestate treatment did not increase soil–plant transfer of the elements, except Ga in F. esculentum. However, the addition of sewage sludge increased shoot Cd contents in all species. Moreover, F. esculentum responded with a higher accumulation of Ga and L. albus accumulated more As and REE, while shoot accumulation remained unchanged in other species. Our findings suggest species-specific differences in the utilization of labile element pools that most likely derive from altered rhizosphere chemistry, where processes related to element acquisition depend on the plant's nutritional status.
Epidemiological disease burden and annual, nationwide health insurance treatment cost of female infertility based on real-world health insurance claims data in Hungary
Authors: Pónusz-Kovács Dalma , Csákvári Tímea , Sántics-Kajos Luca Fanni , Elmer Diána , Pónusz Róbert , Kovács Bettina , Várnagy Ákos , Kovács Kálmán , Bódis József , Boncz Imre 
Published: October 2023

Abstract

Background:Infertility affects more than 50 million couples worldwide, resulting in a significant burden on individuals and society. Its prevalence ranges from 8-12% among developed countries. The growing number of patients poses an increasing challenge to the healthcare system and its funding. Our quantitative, descriptive, and cross-sectional study aims to analyze the prevalence and annual nationwide health insurance treatment cost of female infertility in Hungary in 2019.
Methods: We used claims data obtained from the Hungarian National Health Insurance Fund Administration (NHFIA). The number of patients, total and age-specific prevalence, annual health insurance expenditure, and the distribution of costs by age group were evaluated. Infertility was determined according to the World Health Organization International Classification of Diseases codes (N.97.0, N97.1, N97.2, N97.3, N97.4, N97.8, N97.9) and the utilization of each healthcare service type. During the study descriptive statistics, correlation analysis and ANOVA were used.
Results: In 2019, the NHIFA spent a total of 7.2 billion HUF (22.2 million EUR) on female infertility treatment in Hungary. The most significant costs were related to inpatient care (4.1 billion HUF, 12.7 million EUR). The highest number of patients and prevalence (33,151 women, 650.4 per 100,000 women) were found in outpatient care. In inpatient care, the prevalence is substantially lower (206.7 per 100,000 women). Female infertility, regardless of its type, mainly affects patients in the 30-39 age group (number of patients: 18,156 women). The average annual health insurance expenditure per capita was 1,083 EUR.
Conclusions: Reproductive health education, prevention, and medical screening play an inevitable role in the early stages of reproductive life to reduce the risk of infertility and decrease the costs of treatment.
Sustainable Biodiesel Production via Chlorella vulgaris and Tetraselmis chuii in food-based brewery Industrial Wastewater
Authors: Hussain Syed Babar , Shah Syed Muhammad Usman , Nosheen Asia , Mumtaz Saqib 
Published: October 2023

Abstract
The microalgae Chlorella vulgaris and Tetraselmis chuii offer several attractive attributes as an aquaculture feed. Biomass production of T. chuii and C. vulgaris is relatively expensive because it requires high operation and substrate cost. Use of food industry waste is one of the promising solutions to reduce the substrate cost. In this research the impact of diverse concentration was filtered and centrifuged, food wastewater (FWW) was scrutinized as an alternative intermediate for microalgal bioremediation, lipid yield and cell growth. Both the tested species C. vulgaris and T. chuii showed highest lipid accumulation and cell growth at 75% level of food-based industrial wastewater with the maximum specific growth rate (0.27 d− 1), maximum biomass formation rate (0.1–0.18 gL− 1 d− 1) and lipid content (33.80 ± 0.88–35.04 ± 2.05%) respectively. The microalgal cells not only improved with food wastewater feeding but the level of COD (80.97–66.17%), BOD (81.13–66.81%), TN (55.88–22.06%) and certain heavy metals like zinc (99.72–99.52%), manganese (72.09–65.17%), nickel (50.68–34.41%), NO3N (50.68–42.59%), ferric (57.14–65.71%), cadmium (83.51–86.64%), lead (48.83–97.21%) and arsenic (55.13–55.00%) were also efficiently removed from food wastewater (FWW) at different diluted concentrations. C18:0/C18:1 was obtained as the major fatty acids in lipid which showed a vast potential of ADW007 for biodiesel fabrication and instantaneous bioremediation procedure using FWW.
Antagonistic effects of Beauveria bassiana against seed-borne fungi of cowpea (Vigna unguiculata)
Authors: Pachoute Julner , Santos Gil Rodrigues dos , de Souza Danival José 
Published: October 2023

Abstract
Cowpea is cultivated worldwide as a source of protein, but various factors limit its yield. Besides climatic challenges and pest attacks, farmers face pathogens to keep crop productivity. Fungi stood out among its main pathogens. They are generally transmitted by seeds and spread over a long distance through infected seeds. In this sense, this study aimed to assess the diversity of seed-borne fungi associated with cowpea and evaluate the antagonistic effect of B. bassiana on the phytopathogen fungi in vivo and in vitro. A seed health test was performed using the blotter test method. The isolated phytopathogens were molecularly identified and submitted to Koch's postulates. Antagonistic effects of B. bassiana against the pathogens were tested in vitro using the paired culture method and in vivo by inoculating the plant in greenhouse conditions. According to the seed health test result, besides saprophytes (Aspergillus, Penicillium, Rhizopus, Mucor), three pathogens fungi were identified (Fusarium sp., Alternaria aff. burnsii, Epicoccum sp.). In the antagonistic tests and in vitro assays, B. bassiana showed greater growth inhibition of Fusarium sp. isolate JP1. Alternaria burnsii isolate JP2 was inhibited from 18,54 to 35,67% and Epicoccum sp from 22,73 to 25,23%. The inoculation of the plants with B. bassiana reduced Fusarium symptoms to 58,33%, Alternaria aff. burnsii to 40,08%, Epicoccum sp. to 22,22%. This report is the first to isolate Epicoccum sp. in cowpea seed in Brazil and its inhibition by B. bassiana.
The effects of cGAS-Sting pathway on bone mineral density
Authors: Liu Lifei , Tong Xiaoyang , Huang Mei , Zhu Chenyu , Chen Xi , Yuan Yu , Bennett Samuel , Xu Jiake , Zou Jun 
Published: October 2023

Abstract
The cGAS-Sting pathway plays an essential role in a variety of pathological processes, such as inflammation, infection and cancer. It has recently been found to affect bone metabolism, but the exact role is not well understood. We studied the effect of both cGAS gene KO and Sting gene KO mice on bones, and assessed the effects of Sting gene in osteoclast differentiation and osteoblast and formation in vivo. This study found that Sting KO mice but not in cGAS KO mice exhibited a decreased BV/TV and Tb.N, as evident by the micro CT analyses. At the cellular level, Sting deficiency was revealed to promote osteoclastogenesis and inhibit osteoblastogenesis, accompanied with increased phosphorylation of p-38 in osteoclasts and decreased phosphorylation of β-Catenin in bone marrow stromal cells (BMSCs). Our study showed that the absence of cGAS gene had no significant effect on bone density, whereas Sting gene deficiency reduced bone formation in mice, which provides a possible new target for the treatment of osteoporosis.