bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing SilverSil Sol–Gel Chemistry Toward Practical Application
Authors: Li Petri Giovanna , Ciriminna Rosaria , Pagliaro Mario 
Published: January 2025

AbstractConsisting of organically‐modified silica entrapping silver nanoparticles originally derived from methyltriethoxysilane (MTES) and tetraethylorthosilicate (TEOS) only, the SilverSil sol–gel coating shows significant antimicrobial activity (in vitro). Now, we report the outcomes of investigation aimed at developing SilverSil coatings to functionalize textiles. We investigate the use of 3‐(aminopropyl)trimethoxysilane (APTMS) to stabilize the SilverSil nanosol precursor and increase the Ag nanoparticle encapsulation efficiency. We further study the effect of selected parameters of the sol–gel polycondensation process in sight of practical application of SilverSil as a low‐cost antibacterial coating of broad scope and limited antimicrobial resistance.
Enhancing Zn Deposition Reversibility on MXene Current Collectors by Forming ZnF2‐Containing Solid‐Electrolyte Interphase for Anode‐Free Zinc Metal Batteries
Authors: Chen Chaofan , Guo Rui , Ganapathy Swapna , Terpstra Baukje , Wang Hao , Lei Zhibin , Ooms Frans , Boshuizen Bart , Wagemaker Marnix , Bannenberg Lars J. , Wang Xuehang 
Published: January 2025

AbstractAnode‐free aqueous zinc metal batteries (AZMBs) offer significant potential for energy storage due to their low cost and environmental benefits. Ti3C2Tx MXene provides several advantages over traditional metallic current collectors like Cu and Ti, including better Zn plating affinity, lightweight, and flexibility. However, self‐freestanding MXene current collectors in AZMBs remain underexplored, likely due to challenges with Zn deposition reversibility. This study investigates the combination of a Ti3C2Tx self‐freestanding film with advanced electrolyte engineering, specifically examining the effects of Li‐salt and propylene carbonate (PC) as additives on Zn plating reversibility. While using Li+ ions as an additive alone facilitates uniform Zn deposition on bulk metals through the electrostatic shielding effect, the addition of Li‐salt negatively impacts Zn plating uniformity on Ti3C2Tx. Meanwhile, using PC additive alone forms an organic SEI layer on Ti3C2Tx and causes Zn agglomeration. The use of both additives together results in a ZnF2‐containing hybrid SEI layer with improved interfacial kinetics, promoting more uniform Zn deposition. This approach achieves an average Coulombic efficiency (CE) of 96.8% over 150 cycles (a maximum CE of 97.8%). The study highlights the strategic difference in electrolyte design, emphasizing the need for tailored approaches to optimize Zn deposition on MXenes, contrasting with traditional metallic current collectors.
Activating Reversible V4+/V5+ Redox Couple in NASICON‐Type Phosphate Cathodes by High Entropy Substitution for Sodium‐Ion Batteries
Authors: Wang Siya , Bai Jin , Wang Peiyao , Mao Yunjie , Xiao Ke , Liu Yuanyuan , Qiu Shiyu , Zhu Xuebin , Zhao Bangchuan , Sun Yuping 
Published: January 2025

AbstractVanadium‐based Na superionic conductor (NASICON) type materials (NaxVM(PO4)3, M = transition metals) have attracted extensive attention when used as sodium‐ion batteries (SIBs) cathodes due to their stable structures and large Na+ diffusion channels. However, the materials have poor electrical conductivity and mediocre energy density, which hinder their practical applications. Activating the V4+/V5+ redox couple (V4+/V5+≈4.1 V vs Na+/Na) is an effective way to elevate the energy density of SIBs, whereas the irreversible phase transition of V4+/V5+ and severe structural distortion will inevitably result in fast capacity fading and unsatisfactory rate capability. Herein, a high entropy regulation strategy is proposed to optimize the detailed crystal structure and improve the reversibility of crystalline phase transformation and electrical conductivity of the material. With the activated reversible V4+/V5+ redox couple, stable structure, and fast electrochemical kinetics, the high entropy material Na3.2V1.5Fe0.1Al0.1Cr0.1Mn0.1Cu0.1(PO4)3 (NVMP‐HE) exhibits an outstanding electrochemical performance with highly reversible specific capacity of 120.1 mAh g−1 at 0.1 C and excellent cycling stability (92.4% retention after 1000 cycles at 20 C). Besides, the in situ X‐ray diffraction (XRD) measurement reveals that a smooth three‐phase transition reaction is involved in this high‐entropy cathode and the existence of mesophase facilitates a fast phase transition.
Exploring ChatGPT's Potential in Java API Method Recommendation: An Empirical Study
Authors: Wang Ye , Xue Weihao , Huang Qiao , Jiang Bo , Zhang Hua 
Published: January 2025

ABSTRACTAs software development grows increasingly complex, application programming interface (API) plays a significant role in enhancing development efficiency and code quality. However, the explosive growth in the number of APIs makes it impossible for developers to become familiar with all of them. In actual development scenarios, developers may spend a significant amount of time searching for suitable APIs, which could severely impact the development process. Recently, the OpenAI's large language model (LLM) based application—ChatGPT has shown exceptional performance across various software development tasks, responding swiftly to instructions and generating high‐quality textual responses, suggesting its potential in API recommendation tasks. Thus, this paper presents an empirical study to investigate the performance of ChatGPT in query‐based API recommendation tasks. Specifically, we utilized the existing benchmark APIBENCH‐Q and the newly constructed dataset as evaluation datasets, selecting the state‐of‐the‐art models BIKER and MULAREC for comparison with ChatGPT. Our research findings demonstrate that ChatGPT outperforms existing approaches in terms of success rate, mean reciprocal rank (MRR), and mean average precision (MAP). Through a manual examination of samples in which ChatGPT exceeds baseline performance and those where it provides incorrect answers, we further substantiate ChatGPT's advantages over the baselines and identify several issues contributing to its suboptimal performance. To address these issues and enhance ChatGPT's recommendation capabilities, we employed two strategies: (1) utilizing a more advanced LLM (GPT‐4) and (2) exploring a new approach—MACAR, which is based on the Chain of Thought methodology. The results indicate that both strategies are effective.
Improving Spatial Transcriptomics with Membrane‐Based Boundary Definition and Enhanced Single‐Cell Resolution
Authors: Song Li , Wang Liqun , He Zitian , Cui Xiao , Peng Cheng , Xu Jie , Yong Zhouying , Liu Yanmei , Fei Ji‐Feng 
Published: January 2025

AbstractAccurately defining cell boundaries for spatial transcriptomics is technically challenging. The current major approaches are nuclear staining or mathematical inference, which either exclude the cytoplasm or determine a hypothetical boundary. Here, a new method is introduced for defining cell boundaries: labeling cell membranes using genetically coded fluorescent proteins, which allows precise indexing of sequencing spots and transcripts within cells on sections. Use of this membrane‐based method greatly increases the number of genes captured in cells compared to the number captured using nucleus‐based methods; the numbers of genes are increased by 67% and 119% in mouse and axolotl livers, respectively. The obtained expression profiles are more consistent with single‐cell RNA‐seq data, demonstrating more rational clustering and apparent cell type‐specific markers. Furthermore, improved single‐cell resolution is achieved to better identify rare cell types and elaborate spatial domains in the axolotl brain and intestine. In addition to regular cells, accurate recognition of multinucleated cells and cells lacking nuclei in the mouse liver is achieved, demonstrating its ability to analyze complex tissues and organs, which is not achievable using previous methods. This study provides a powerful tool for improving spatial transcriptomics that has broad potential for its applications in the biological and medical sciences.
Reinforced Piled Embankment with Subsoil in Plane Strain and Three-Dimensional Conditions
Authors: Zhuang Yan 
Published: January 2025

Abstract
In Chap. 4, the authors considered predictions of reinforcement tension in a piled embankment based on British standard BS 8006 published in 2010 and the 2012 amended version, and compared the results with finite-element model predictions.
Pelvic ring fracture and erectile dysfunction (PERFECD) – 3 year follow-up cross sectional study
Authors: Rizzoli Gioia , Schmid Florian A. , Kessler Franziska , Kalbas Yannik , Klingebiel Felix Karl-Ludwig , Berk Till , Pfeifer Roman , Eberli Daniel , Pape Hans-Christoph , Halvachizadeh Sascha 
Published: January 2025

Abstract

Introduction
Pelvic ring fractures are known to be associated with complications associated with adjacent organ injuries, such as the urogenital tract (e.g. erectile dysfunction (ED), which are sometimes diagnosed in a delayed fashion. Therefore, we assessed the quality of life (QoL) and the rate of erectile dysfunction (ED) following pelvic ring fractures at a minimum of 3 years after pelvic ring injury.

Methods
Between January 1, 2016, and December 31, 2020, adult male patients (≥ 18 years) with pelvic ring injuries were included in the study. Fractures were classified according to the Young & Burgess (Y&B) classification system, while pelvic contusions were categorized as the control group. Data were collected using a written questionnaire that assessed Quality of Life (QoL) by Short Form 12 (SF-12) and erectile dysfunction (ED) with the International Index of Erectile Function 5 (IIEF-5). ED was stratified as follows: no ED (21–25 points), mild ED (16–21 points), moderate ED (9–15 points), and severe ED (5–7 points). Comorbidities and risk factors for ED were also assessed, including vasculopathy, peripheral artery disease, hypercholesterolemia, coronary artery disease, diabetes, and smoking.

Results
A total of 182 patients were included, with a mean age at injury of 53.5 years (SD 17.1) and a mean age at the time of the questionnaire of 57.8 years (SD 17.4). The distribution of patients was as follows: APC Group (n = 20, 11.1%), LC Group (n = 94, 52.2%), CMVS Group (n = 6, 3.3%), and Control Group (n = 60, 33.3%). The mean Injury Severity Score (ISS) was 24.6 points (SD 16.4). Regarding erectile dysfunction, 8 patients (17.4%) had no ED, 10 (21.7%) had mild ED, 6 (13.0%) had moderate ED, and 22 (47.8%) had severe ED. Quality of Life (QoL) was significantly reduced in patients with CMVS pelvic fractures, particularly in physical role function, which scored 62.5 points (SD 29.6, p < 0.001). All patients in the APC Group reported at least a mild form of ED. APC injuries were identified as an independent risk factor for lower IIEF-5 scores (OR -4.5, 95% CI -8.3 to -0.7, p = 0.02), comparable to other risk factors such as hypertension (OR -9.2, 95% CI -12.8 to -5.6, p < 0.001), diabetes (OR -5.3, 95% CI -9.4 to -1.2, p = 0.012), and smoking (OR -2.6, 95% CI -5.2 to -0.04, p = 0.05).

Conclusion
Vertical shear fractures are associated with significantly lower quality of life compared to APC or LC fractures three years post-injury. The APC type of pelvic ring injury was identified as an independent risk factor for the development of erectile dysfunction (ED). Early screening and appropriate management should be initiated for patients with APC injuries to address and mitigate the risk of ED.
Plastisch-chirurgische Therapie der Neurofibromatose Typ 1
Authors: Längle Gregor , Gohritz Andreas , Gstöttner Clemens , Harnoncourt Leopold , Platzgummer Hannes , Azizi Amedeo A. , Aszmann Oskar 
Published: January 2025

Zusammenfassung
Die Neurofibromatose Typ 1 (NF1, früher Morbus Recklinghausen) ist ein genetisches Tumorprädispositionssyndrom, bei dem die Mutation eines Tumorsuppressorgens (Neurofibromin) zur Ausbildung meist gutartiger Neurofibrome der Haut und des zentralen und peripheren Nervensystems und Fehlbildungen oder Tumoren anderer Organsysteme führt. Patient:innen mit NF1 sollten lebenslang in spezialisierten Zentren interdisziplinär betreut werden, wichtige Therapieentscheidungen sollten hier in einem regelmäßig stattfindenden interdisziplinären Expertengremium getroffen werden. Die plastische Chirurgie spielt in der Behandlung aller klinischen Formen der NF1-assoziierten Nervenscheidentumoren eine wichtige Rolle – von kutanen und subkutanen bis zu tiefen nodulären und diffusen plexiformen Neurofibromen. Jeder Patient erfordert eine individualisierte chirurgische Planung, wobei Zeitpunkt und Ausmaß der Operationen von Symptomatik, funktionellen und ästhetischen Einschränkungen, Fortschreiten der Krankheit und potenzieller maligner Entartung bestimmt werden. Da jede Körperregion betroffen sein kann, reicht das erforderliche umfassende Spektrum ästhetischer und rekonstruktiver Chirurgie von der Lidplastik und Gesichtswiederherstellung über die Brustformung bis hin zur Nervenrekonstruktion oder motorischen Ersatzoperationen. Ein rechtzeitig durchgeführter chirurgischer Eingriff kann die Krankheitsentwicklung und Lebensqualität der Betroffenen entscheidend beeinflussen und im Fall einer Transformation zum malignen peripheren Nervenscheidentumor (MPNST) sogar lebensrettend sein.
Genetic diversity of murine norovirus associated with ethanol sensitivity
Authors: Wanguyun Aken Puti , Oishi Wakana , Sano Daisuke 
Published: January 2025

Abstract
RNA viruses have high genetic diversity, allowing rapid adaptation to environmental pressures, such as disinfection. This diversity increases the likelihood of mutations influencing the viral sensitivity to disinfectants. Ethanol is widely used to control viral transmission; however, insufficient disinfection facilitates the survival of less-sensitive viruses. Further, the underlying mechanisms of ethanol-induced changes in viral sensitivity remain unclear. Here, we assessed the genetic characteristics of ethanol-adapted murine norovirus (MNV) and associated changes in viral sensitivity. Experimental ethanol-facilitated MNV adaptation and subsequent genetic characteristic evaluation of the whole genome sequence was performed. MNV was exposed to 70% ethanol for 5 s to achieve ± 3-log10 inactivation. Twelve MNV populations were identified as “less sensitive,” consisting of nine treated and three control populations. Less-sensitive MNV populations exhibited significantly higher synonymous nucleotide diversity (πS) in ORF1 (p = 0.001), which encodes the non-structural protein, than sensitive populations. Ethanol sensitivity and πS were negatively correlated in ORF1 (R = − 0.49, p = 0.003), indicating that high genetic diversity in ORF1 could be linked to reduced ethanol sensitivity. This study demonstrates an association between nucleotide diversity in specific coding regions of the MNV genome and ethanol sensitivity. These findings are vital for improving disinfection methods and anticipating emerging viruses that are more resistant to disinfectants.

Key points
• Several MNV populations reduced sensitivity to ethanol.
• Higher synonymous diversity in ORF1 linked to reduced ethanol sensitivity.
• Synonymous mutations can influence viral adaptation to ethanol.
Imaging on the painful and compressed nerve: lower extremity
Authors: Bordalo Marcelo 
Published: January 2025

Abstract
Entrapment neuropathies of the lower extremity are often underdiagnosed due to limitations in clinical examination and electrophysiological testing. Advanced imaging techniques, particularly MR neurography and high-resolution ultrasonography (US), have significantly improved the evaluation and diagnosis of these conditions by enabling precise visualization of nerves and their surrounding anatomical structures. This review focuses on the imaging features of compressive neuropathies affecting the lumbosacral plexus and its branches, including the femoral, obturator, sciatic, common peroneal, and tibial nerves. Key conditions such as meralgia paraesthetica, piriformis syndrome, and tarsal tunnel syndrome are discussed, highlighting findings such as nerve thickening, T2 hypersignal, fascicular changes, and associated muscle denervation patterns. The ability to detect structural causes, including anatomical variations, fibrous bands, and space-occupying lesions, underscores the value of these imaging modalities in facilitating early diagnosis, guiding therapeutic interventions, and improving patient outcomes.
Dehydration rapidly induces expression of NCED genes from a single subclade in diverse eudicots
Authors: Vo Hanh M. , Charleston Michael A. , Brodribb Timothy J. , Sussmilch Frances C. 
Published: January 2025

Abstract

Main conclusion
A gene within a single subclade of NCED genes is triggered in response to both, short- and long-term dehydration treatments, in three model dicot species.

Abstract
During dehydration, some plants can rapidly synthesise the stress hormone abscisic acid (ABA) in leaves within 20 min, triggering the closure of stomata and limiting further water loss. This response is associated with significant transcriptional upregulation of Nine-cis-Epoxycarotenoid Dioxygenase (NCED) genes, which encode the enzyme considered to be rate-limiting in ABA biosynthesis. However, most embryophyte species possess multiple NCED genes, and it is not currently known whether there is any phylogenetic pattern to which NCED genes are involved in this response. We tested transcriptional responses to dehydration for all NCED genes present in three diverse eudicot species—Arabidopsis thaliana (Arabidopsis), pea and tomato—over both the timeframe of stomatal responses (< 20 min) and in response to sustained dehydration (hours). We found that there is a single NCED gene per species, AtNCED3, PsNCED2, and SlNCED1, respectively, that is rapidly upregulated by dehydration. Using a null mutant, we confirmed that the rapidly responsive gene identified in Arabidopsis is important for physiological responses to a sudden drop in humidity. Analysis of the relationships and the evolutionary history of NCED genes using available sequence data from diverse land plant species revealed that the identified genes in each species all belong to the same subclade within the gene family, suggesting a conserved role for this subclade in rapid dehydration responses in eudicots. These findings enable future phylogenetically-informed prediction of genes of interest for rapid dehydration responses within this important multigene family in eudicot species.
Practitioners’ perspective: a mixed-methods study on dealing with suicidality from the perspective of oncological healthcare professionals
Authors: Schwinn Tamara , Hirschmiller Judith , Wiltink Jörg , Zwerenz Rüdiger , Brähler Elmar , Beutel Manfred E. , Ernst Mareike 
Published: January 2025

Abstract

Purpose
Healthcare professionals (HCPs) play a critical role in suicide prevention and clinical guidelines recommend inquiring about suicidality as part of medical history and diagnosis. Emerging evidence indicates a lack of implementation of such policies in clinical practice. However, to date, no comprehensive mixed-methods study has examined this issue in the field of oncology.

Methods
A preregistered mixed-methods study was conducted with oncological HCPs (N = 20) from various professions, using semi-structured interviews and validated questionnaires. Employing an explorative theory-generating approach, qualitative content analysis was applied to the interviews. The different data sources are integrated and contrasted. Comparisons according to sociodemographic variables (profession, age, and gender) and frequency distributions were used to examine the questionnaire data.

Results
Most HCPs reported direct or indirect experiences with suicidality in cancer patients. Nineteen HCPs did not routinely explore suicidality, of whom five reported not inquiring about it at all. Those who explored suicidality were more confident, less emotionally overwhelmed and reported higher subjective knowledge. HCPs also differed regarding their endorsement of suicide myths.

Conclusion
The study highlights difficulties with active suicide exploration and differences among HCPs. Integrating these findings into education and training could improve HCPs’ skills and reduce disparities, supporting successful suicide prevention.
The citizen perspective on challenges and rehabilitation needs among individuals treated for head and neck cancer: a qualitative study
Authors: Jacobsen Kathrin Fríðunn Astrup Brøgger , Mikkelsen Lene Kronborg , Jørgensen Lone 
Published: January 2025

Abstract

Purpose
In Denmark, the prevalence of head and neck cancer is approximately 17.000, and the incidence is increasing. The disease and treatment of this condition may lead to severe physical, psychological, and social consequences. However, the literature indicates a lack of rehabilitation services and insufficient professional resources in the municipal setting resulting in unmet rehabilitation needs. The aim of this study is to gain an understanding of the challenges and rehabilitation needs experienced by citizens treated for head and neck cancer.

Methods
A qualitative study using semi-structured interviews was employed. Paul Ricoeur’s interpretation theory was used to analyze the data.

Findings
Citizens treated for head and neck cancer experience the need for targeted assistance to manage the consequences following treatment for head and neck cancer and the need for adequate information and specialized professional competencies in municipal rehabilitation. The findings highlight a dual need: support from healthcare professionals and opportunities for patients to connect with others who have undergone treatment for head and neck cancer, as part of municipal rehabilitation.

Conclusion
The study contributes to an understanding of the citizen perspective on rehabilitation needs and informs and enhances knowledge about municipal rehabilitation interventions for citizens treated for head and neck cancer. However, the findings also indicate the complexity of the referral process, highlighting the need for further research on barriers and facilitators to referral and access to municipal rehabilitation.
Experimental Investigation of Burst Failure Mechanism Under Polyaxial Loading Conditions
Authors: Akdag Selahattin , Karakus Murat , Nguyen Giang D. 
Published: January 2025

Abstract
Effective monitoring and early warning methods are crucial for enhancing safety and sustainability in deep resource extraction, which are particularly important for mitigating rock/coal burst failures. This study introduces a newly modified thick-walled hollow cylinder (TWHC) testing system for rock and coal burst at the laboratory scale. Fracture initiation and propagation, leading to bursting on the wall of a cylindrical opening in granite, bluestone and coal are characterised by real-time acoustic emission (AE) responses. In this study, a borescope was used synchronously to observe the dynamic failure processes of rock/coal bursts and to verify AE results. The internal fracture morphologies of granite, bluestone and coal specimens were acquired using X-ray micro-Computed Tomography (μCT). We analysed the intrinsic mechanism of strain energy evolution of bursting and found that the average energy consumed by the induced cracking and released kinetic energy during bursting is approximately ~ 8, 25 and 18% of the total absorbed strain energy of granite, bluestone and coal, respectively. We found the average mass of the ejected rock/coal fragments to be ~ 0.3–0.5 g, whilst the rock/coal ejection velocity ranged from 10.5 to 19.8 m/s for the hollow coal, bluestone and granite. The results also indicate that granite and bluestone have the highest potential for violent bursting failure.