bluuebunny/crossref_metadata_2025_split huggingface dataset:
Variables that explain disordered eating behaviors among women: the mediating role of body dissatisfaction
Authors: Franco-Paredes Karina , Díaz-Reséndiz Felipe J. , Peláez-Fernández María Angeles , Bautista-Díaz María Leticia 
Published: January 2024

Abstract
Purpose
To analyze the role of body dissatisfaction in the relationships of sociocultural influences, depression, and anxiety with disordered eating behaviors (DEB) in a sample of female Mexican university students.

Methods
A nonrandom sample of 526 female Mexican university students aged 18 to 25 years completed the Questionnaire of Influence on the Aesthetic Model of Body Shape (CIMEC-26), the Hospital Anxiety and Depression Scale (HADS), the Body Shape Questionnaire (BSQ-8D) and the Eating Attitudes Test (EAT-26).

Results
Through the mean model (χ2/df (5, n = 526) = 7.298, p = .199; NFI = .996; CFI = .999; RMSEA = .030; SRMR = .011), body dissatisfaction was found to mediate the relationships of influence of advertising, influence of social models and anxiety with DEB (restrictive dieting and bulimia). The variable with the most direct effect on restrictive dieting and bulimia was the influence of advertising. Body dissatisfaction partially mediated this relationship, as the influence of advertising had a significant direct effect on restrictive dieting and bulimia. The final model of direct and indirect effects explained 43% and 22% of the variance in restrictive dieting and bulimia, respectively.

Conclusion
The present study showed that body dissatisfaction partially mediated the relationships between influence of advertising, influence of social models, and anxiety with DEB among women. Thus, these variables should be taken into account in prevention and intervention programs targeting BED. Level V: Evidence obtained from a cross-sectional descriptive study.

Level V
Evidence obtained from a cross-sectional descriptive study.
Foramen ovale as a new determinative sign for the identification of tiger (Panthera tigris) and lion (Panthera leo) skulls
Authors: Formanova Dominika , Pyszko Martin , Horak Ondrej , Sadkova Jolana , Rihova Pavla , Kubatova Anna 
Published: January 2024

AbstractTiger and lion bones are valued highly on the wildlife black market. The skeletons of the two species are very similar, but the level of protection and the laws applicable to them differ. When detecting crime in the field, it can be crucial to recognize the skeletons of these two species by their morphological features. A distinguishing feature neglected in practice is the foramen ovale at the base of the skull. A total of 112 skulls were evaluated (55 tigers and 57 lions). The orientation and appearance of the foramina ovalia were analyzed on skull photographs. Significant differences were found between tigers and lions. In lions, the foramina ovalia faced laterally and their outlets were usually at least partially hidden behind the straight edge of the os basisphenoidale from the ventral view of the skull. In most adult tigers, the foramina ovalia faced more rostrally with their outlets visible and bounded by a semi-circular edge of the os basisphenoidale. However, tiger skulls exhibited higher variability in foramina ovalia orientation than lion skulls. Like other identifying features on tiger and lion skulls, the foramen ovale was unable to distinguish all skulls with 100% confidence. Nevertheless, knowledge of this structure can help considerably in species identification.
US FDA’s Dose Optimization Postmarketing Requirements and Commitments of Oncology Approvals and the Impact on Product Labels from 2010 to 2022: An Emerging Landscape from Traditional to Novel Therapies
Authors: Gendy Joseph M. , Nomura Naomi , Stuart Jeffrey N. , Blumenthal Gideon 
Published: January 2024

Abstract
Background
Dose optimization is a focal point of many US Food and Drug Administration (FDA) drug approvals. We sought to understand the impact of the FDA’s Postmarketing Commitments/Postmarketing Requirements (PMCs/PMRs) on dose optimization and prescriber labeling for oncology drugs.

Methods
Publicly available information was aggregated for all FDA oncology drug approvals between January 1, 2010, and December 31, 2022. Study completion dates were compared to product labeling before and after PMC/PMR fulfillment dates to evaluate labeling changes associated with dose-related PMCs/PMRs. Data were analyzed individually (2010–2015 and 2016–2022) due to differences in available information.

Results
From 2010 to 2015, 14 of 42 (33.3%) new molecular entities (NMEs) had dose-related PMCs/PMRs, with 6 of 14 (42.9%) resulting in a relevant label change. From 2016 to 2022, of the 314 new or supplemental applications approved, 21 had dose-related PMCs/PMRs (6.7%), which trended upward over time; 71.4% of dose-related PMCs/PMRs were NMEs. Kinase inhibitors (KIs) and antibody/peptide drug conjugates (ADCs/PDCs) were the most affected drug classes. Ten of the 21 approvals with dose-related PMCs/PMRs fulfilled their dosing PMCs/PMRs, and 3 of the 10 (30%) had relevant label changes.

Conclusion
Most dose-related PMRs/PMCs were issued for NMEs. Of these, KIs and ADCs/PDCs were highly represented, reflecting their novelty and greater uncertainty around their safety profile. PMC/PMR issuance broadly increased over time. With the implementation of the FDA’s Project Optimus in 2021, it remains to be seen whether fewer dose-related PMCs/PMRs emerge in future due to enhanced dose optimization in the premarketing setting.
ECS: an interactive tool for data quality assurance
Authors: Sieberichs Christian , Geerkens Simon , Braun Alexander , Waschulzik Thomas 
Published: January 2024

AbstractWith the increasing capabilities of machine learning systems and their potential use in safety-critical systems, ensuring high-quality data is becoming increasingly important. In this paper, we present a novel approach for the assurance of data quality. For this purpose, the mathematical basics are first discussed and the approach is presented using multiple examples. This results in the detection of data points with potentially harmful properties for the use in safety-critical systems.
Assessing systematic weaknesses of DNNs using counterfactuals
Authors: Gannamaneni Sujan Sai , Mock Michael , Akila Maram 
Published: January 2024

AbstractWith the advancement of DNNs into safety-critical applications, testing approaches for such models have gained more attention. A current direction is the search for and identification of systematic weaknesses that put safety assumptions based on average performance values at risk. Such weaknesses can take on the form of (semantically coherent) subsets or areas in the input space where a DNN performs systematically worse than its expected average. However, it is non-trivial to attribute the reason for such observed low performances to the specific semantic features that describe the subset. For instance, inhomogeneities within the data w.r.t. other (non-considered) attributes might distort results. However, taking into account all (available) attributes and their interaction is often computationally highly expensive. Inspired by counterfactual explanations, we propose an effective and computationally cheap algorithm to validate the semantic attribution of existing subsets, i.e., to check whether the identified attribute is likely to have caused the degraded performance. We demonstrate this approach on an example from the autonomous driving domain using highly annotated simulated data, where we show for a semantic segmentation model that (i) performance differences among the different pedestrian assets exist, but (ii) only in some cases is the asset type itself the reason for this reduction in the performance.
Preparation of high-performance manganese-based pseudocapacitor material by using spent lithium-ion battery anode graphite via mechanochemical pretreatment
Authors: Dai Lujie , Li Bang , Li Jia , Xu Zhenming 
Published: January 2024

AbstractThe potential for recycling graphitic carbon from lithium-ion battery (LIB) anodes has been overlooked due to its relatively low economic value in applications. This study proposed to use graphene nanoplates (GNPs), which were obtained from spent lithium battery anode graphite, treated with ball-milling method, for hydrothermal synthesis of MnO2-supported graphene nanoplates (MnO2/GNPs) composites materials. The composites exhibited excellent electrochemical characterization curves, indicating ideal capacitance characteristics. The analysis of MG24-20 material showed the good impact resistance and capacity retention around 100% with capacitance of 124.6F/g at 10 mV/s, surpassed similar samples using precious metals and high-end materials, enabling the reuse of spent graphite in energy conversion and storage system for effective utility.
Graphical Abstract
Life-Course Socioeconomic Position and Mild Cognitive Impairment in Midlife: Evidence from the 1958 British Birth Cohort
Authors: Sahota Chanthie Menika , Cable Noriko , Cadar Dorina 
Published: January 2024

Abstract
Background
Dementia has been the leading cause of death in the UK since 2015. Increasing evidence supports an association between socioeconomic position (SEP) and dementia onset in later life. However, limited studies have examined how life-course SEP influences the development of mild cognitive impairment (MCI), an intermediate state potentially preceding dementia. Therefore, the present study aims to examine the relationship between life-course SEP and MCI amongst adults aged 50 years in Great Britain.

Methods
We employed data from the National Child Development Study (NCDS), also known as the 1958 British Birth Cohort, to determine the associations between SEP and MCI in 6590 participants. We categorised life-course measures of SEP as stable high/low or moving upward/downward over the life course. We assessed MCI at age 50 using one standard deviation below the averaged combined scores from all cognitive tests available. We then used binary logistic regression to estimate the longitudinal associations between life-course SEP and MCI.

Results
Relative to those of a high SEP across the life course, participants who moved upward, downward, or remained at a low SEP were significantly associated with 25% (95% CI 1.02–1.54, p = 0.035), 70% (95% CI 1.27–2.27, p < 0.001), and 85% (95% CI 1.50–2.29, p < 0.001), respectively, higher odds of MCI, independent of all selected covariates.

Conclusions
Lower life-course SEP was associated with significantly higher odds of MCI onset in middle life within the NCDS cohort. Public health policies targeting cognitive impairment should encompass a life-course approach to reduce socioeconomic inequalities.
Association of Paternal Age Alone and Combined with Maternal Age with Perinatal Outcomes: A Prospective Multicenter Cohort Study in China
Authors: Yin Shaohua , Zhou Yubo , Zhao Cheng , Yang Jing , Yuan Pengbo , Zhao Yangyu , Qi Hongbo , Wei Yuan 
Published: January 2024

Abstract
Maternal and paternal age at birth is increasing globally. Maternal age may affect perinatal outcomes, but the effect of paternal age and its joint effect with maternal age are not well established. This prospective, multicenter, cohort analysis used data from the University Hospital Advanced Age Pregnant Cohort Study in China from 2016 to 2021, to investigate the separate association of paternal age and joint association of paternal and maternal age with adverse perinatal outcomes. Of 16,114 singleton deliveries, mean paternal and maternal age (± SD) was 38.0 ± 5.3 years and 36.0 ± 4.1 years. In unadjusted analyses, older paternal age was associated with increased risks of gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy, preeclampsia, placenta accreta spectrum disorders, placenta previa, cesarean delivery (CD), and postpartum hemorrhage, preterm birth (PTB), large-for-gestational-age, macrosomia, and congenital anomaly, except for small-for-gestational-age. In multivariable analyses, the associations turned to null for most outcomes, and attenuated but still significant for GDM, CD, PTB, and macrosomia. As compare to paternal age of < 30 years, the risks in older paternal age groups increased by 31–45% for GDM, 17–33% for CD, 32–36% for PTB, and 28–31% for macrosomia. The predicted probabilities of GDM, placenta previa, and CD increased rapidly with paternal age up to thresholds of 36.4–40.3 years, and then plateaued or decelerated. The risks of GDM, CD, and PTB were much greater for pregnancies with younger paternal and older maternal age, despite no statistical interaction between the associations related to paternal and maternal age. Our findings support the advocation that paternal age, besides maternal age, should be considered during preconception counseling.

Trial Registration NCT03220750, Registered July 18, 2017—Retrospectively registered, https://classic.clinicaltrials.gov/ct2/show/NCT03220750.
Cutaneous Leishmaniasis Hampers COVID-19: A Controlled Cross-Sectional Study in High-Burden Endemic Areas of Iran
Authors: Bamorovat Mehdi , Sharifi Iraj , Shafiei Bafti Mehdi , Agha Kuchak Afshari Setareh , Aflatoonian Mohammad Reza , Karamoozian Ali , Jafarzadeh Abdollah , Amirzadeh Raheleh , Khosravi Ahmad , Babaei Zahra , Safa Farzane , Sharifi Fatemeh , Heshmatkhah Amireh 
Published: January 2024

Abstract
Introduction
Emerging infectious diseases such as SARS-CoV-2 can cause pandemics and create a critical risk for humans. In a previous pilot study, we reported that the immunological responses induced by cutaneous leishmaniasis (CL) could decrease the incidence and severity of COVID-19. In this large-scale case–control study, we assessed the possible relationship between mortality and morbidity of COVID-19 in healed CL persons suffering scars compared to cases without CL history.

Methods
This controlled cross-sectional study was conducted between July 2020 and December 2022 in the endemic and high-burden areas of CL in southeastern Iran. In the study, 1400 previous CL cases with scars and 1,521,329 subjects who had no previous CL were analyzed. We used R 4.0.2 to analyze the data. Firth’s bias reduction approach corresponding to the penalization of likelihood logistic regression by Jeffreys was also employed to influence the variables in the dataset. Also, a Bayesian ordinal logistic regression model was performed to explore the COVID-19 severity in both case and referent groups.

Results
The occurrence and severity rate of COVID-19 in CL scar cases are significantly less than in the non-CL control group, while in the CL scar subjects, patients with critical conditions and mortality were not observed. The morbidity (OR = 0.11, CI 0.06–0.20 and P < 0.001) and severity of COVID-19 in previous cases with CL scars were significantly diminished than that in the control group (credible interval − 2.57, − 1.62).

Conclusions
The results represented a durable negative relationship between cured CL and COVID-19 incidence and severity. Additional studies seem necessary and should be designed to further validate the true impact and underlying mechanistic action of CL on COVID-19.

Graphical abstract
Wind tunnel and numerical study of outdoor particle dispersion around a low-rise building model
Authors: Zhao Runmin , Liu Junjie , Jiang Nan , Liu Sumei 
Published: January 2024

AbstractThe dispersion of particulate pollutants around buildings raises concerns due to adverse health impacts. Accurate prediction of particle dispersion is important for evaluating health risks in urban areas. However, rigorous validation data using particulate tracers is lacking for numerical models of urban dispersion. Many prior studies rely on gas dispersion data, questioning conclusions due to differences in transport physics. To address this gap, this study utilized a combined experimental and computational approach to generate comprehensive validation data on particulate dispersion. A wind tunnel experiment using particulate tracers measured airflow, turbulence, and particle concentrations around a single building, providing reliable but sparse data. Validated large eddy simulation expanded the data. This combined approach generated much-needed validation data to evaluate numerical particle dispersion models around buildings. Steady Reynolds-averaged Navier–Stokes (SRANS) simulations paired with Lagrangian particle tracking (LPT), and drift-flux (DF) models were validated. SRANS had lower accuracy compared to LES for airflow and turbulence. However, in this case, SRANS inaccuracies did not prevent accurate concentration prediction when LPT or a Stokes drift-flux model were used. The algebraic drift-flux model strongly overpredicted the concentration for large micron particles, indicating proper drift modeling was essential.
The Mediation of Autocratic Regimes: How Local Officials Shaped Authoritarian Systems in Rwanda and Sudan
Authors: Desrosiers Marie-Eve , Mahé Anne-Laure 
Published: January 2024

AbstractLocal state officials impact authoritarian systems through the mediation they perform. Desrosiers and Mahé argue that these local functionaries fulfill a number of mediating functions, including translating and representing authoritarian systems at the local level. By enacting these two roles, however, local officials do not straightforwardly reproduce the system. Instead, their interpretations and choices fundamentally influence the imprint authoritarianism has on society, from how the regime is experienced at the local level to its groundings and resilience. They demonstrate this argument by looking at pre-genocide Rwanda and Sudan under President Omar al-Bashir.
Impact of Non-Motor Symptoms on Quality of Life in Patients with Early-Onset Parkinson’s Disease
Authors: Patwardhan Ameya , Kamble Nitish , Bhattacharya Amitabh , Holla Vikram , Yadav Ravi , Pal Pramod Kumar 
Published: January 2024

ABSTRACT:Background:Early-onset Parkinson’s disease (EOPD) refers to patients with Parkinson’s disease (PD) whose age at disease onset is less than 50 years. Literature on the non-motor symptoms (NMS) in these patients is very limited in the Indian context. We aimed to study the NMS in patients with EOPD and its impact on the quality of life (QoL).Methods:We included 124 patients with EOPD with a mean age at disease onset between 21 and 45 years and 60 healthy controls (HC). NMS were assessed using validated scales, and the QoL domains were evaluated using the PD QoL–39 scale (PDQ-39).Results:The mean age at disease onset in EOPD patients was 37.33 ± 6.36 years. Majority of the patients were male (66.12%). The average disease duration was 6.62 ± 5.3 years. EOPD patients exhibited a significantly higher number of NMS per patient (7.97 ± 4.69) compared to HC (1.3 ± 1.39; p < 0.001). The most common NMS reported were urinary dysfunction, body pain, poor sleep quality, constipation, anxiety, depression, cognitive impairment, and REM sleep behavior disorder. The total NMS burden correlated with the QoL measures. Distinctive patterns of QoL subdomain involvement were identified, with sleep/fatigue, mood/cognition, and urinary dysfunction independently influencing QoL metrics.Conclusions:Our study provides valuable insights into the NMS profile and its impact on QoL in patients with EOPD, addressing an important knowledge gap in the Indian context. By understanding the specific NMS and their influence on QoL, healthcare professionals can develop targeted interventions to address these symptoms and improve the overall QoL.
The stable cohomology of self-equivalences of connected sums of products of spheres
Authors: Stoll Robin 
Published: January 2024

Abstract
We identify the cohomology of the stable classifying space of homotopy automorphisms (relative to an embedded disk) of connected sums of

${\mathrm {S}^{k}} \times {\mathrm {S}^{l}}$

, where

$3 \le k < l \le 2k - 2$

. The result is expressed in terms of Lie graph complex homology.
Complexity as Epistemic Oppression: Writing People with Intellectual Disabilities Back into Philosophical Conversations
Authors: Monteleone Rebecca 
Published: January 2024

AbstractFormal LanguageIn this essay, I reflect on the systematic exclusion of people with intellectual disabilities from philosophy even as their personhood is subject to ongoing philosophical debates. Theorizing this disenfranchisement as a form of epistemic oppression, I consider it in the context of the invalidation of disabled perspectives more broadly and characteristics of knowledge-production that confer credibility in philosophy. I end with a call for transformation through the framework of disability justice. I include an Easy Read summary, a plain language companion, and discussion questions, which restate my argument in simplified language and invite dialogue, demonstrating how philosophy might resist epistemic gatekeeping and imagine knowledge-production otherwise.Plain LanguageThis essay is about philosophy and intellectual disability (ID). People with ID do not get to do philosophy very much. Some reasons they are left out are:
–Disabled people are not believed when they talk about their lives.–The way we write in philosophy makes it hard for people with ID to join.I think we should change how we do philosophy. I wrote a summary that is easy to read. I wrote questions to talk about together. I want to think about how to do philosophy better.Easy Read SummaryPhilosophers are thinkers.They think about how the world is and how it should be.They think about intellectual disability (ID).Some thinkers say people with intellectual disabilities (ID) are worth less than other people.Most people with intellectual disabilities (ID) do not get to say what they think.We can change how we think by including people with intellectual disabilities (ID).We can believe what people with intellectual disabilities (ID) say about their lives.We can write and speak in simple ways.We can give people help thinking and making decisions.We can include people who do not speak or write.We can think as a community.
THE BAIRE CLOSURE AND ITS LOGIC
Authors: BEZHANISHVILI G. , FERNÁNDEZ-DUQUE D. 
Published: January 2024

AbstractThe Baire algebra of a topological space X is the quotient of the algebra of all subsets of X modulo the meager sets. We show that this Boolean algebra can be endowed with a natural closure operator, resulting in a closure algebra which we denote
$\mathbf {Baire}(X)$
. We identify the modal logic of such algebras to be the well-known system
$\mathsf {S5}$
, and prove soundness and strong completeness for the cases where X is crowded and either completely metrizable and continuum-sized or locally compact Hausdorff. We also show that every extension of
$\mathsf {S5}$
is the modal logic of a subalgebra of
$\mathbf {Baire}(X)$
, and that soundness and strong completeness also holds in the language with the universal modality.