bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Yoga-based Exercise Program in Female Patients With Myofacial Pain of Temporomandi̇bular Di̇sorders
Authors: ATILGAN ESRA , Kurt Hanefi , Algun Zeliha Candan 
Published: February 2024

Abstract

Objectives: The study was conducted to investigate the effect of Yoga-based exercise program on pain, range of motion (ROM), quality of sleep, depression and quality of life in female patients with myofacial pain of temporomandibular disorders (TMD) .
Materials and Methods: 39 Female patients with myofacial pain of TMD were included in the study. Yoga based exercise program was performed to the first group and second group was control group. Visual Analog Scale (VAS), Neck Pain and Disability Scale (NPDS), neck and jaw ROM, Pittsburg Sleep Quality Index (PUQI), Beck Depression Inventory (BDI) and Short Form 36 (SF36) were evaluated. Evaluations were repeated before treatment and 6 weeks later.
Results: From the measurements, a decrease in chin (p=0.021) and neck pain (p=0.031) was found to be significant in favor of Yoga Group. It was observed that the increase in ROM in the neck right lateral flexion (p=0.045), left rotation (p=0.020) and chin left depression (p=0.034) was in favor of Yoga Group. The sleep quality did not change. In yoga group, a decrease in depression level(p=0,023) and increase Quality of life in parameters of physical function (p=0.023), vital capacity (p=0.026), emotional health (p=0.002), mental health (p=0.080) were found as significant, statistically.
Conclusions: It was concluded that yoga-based exercise program can be used as an alternative program in patients with myofacial pain of TMD. Further study on myofascial pain of TMD is recommended.
Clinical Relevance: Yoga-based exercise program can be used in patients with myofascial pain due to TMD.
The Gammaproteobacteria Epidemiologic Annotation Pipeline
Authors: Dickey Aaron M. , Schmidt John W. , Bono James L. , Guragain Manita 
Published: February 2024

Abstract
Salmonella enterica and Escherichia coli are major food-borne human pathogens, and their genomes are routinely sequenced for clinical surveillance. Computational pipelines designed for analyzing pathogen genomes should both utilize the most current information from annotation databases and increase the coverage of these databases over time. We report the development of the Gammaproteobacteria Epidemiologic Annotation (GEA) pipeline to analyze large batches of E. coli and S. enterica genomes. The GEA pipeline takes as input paired Illumina raw reads files which are then assembled followed by annotation. Alternatively, assemblies can be provided as input and directly annotated. The pipeline provides predictive genome annotations for E. coli and S. enterica with a focus on the Center for Genomic Epidemiology tools. Annotation results are provided as a tab delimited text file. The GEA pipeline is designed for large-scale E. coli and S. enterica genome assembly and characterization using the Center for Genomic Epidemiology command-line tools and high-performance computing. Large scale annotation is demonstrated by an analysis of more than 14,000 Salmonella genome assemblies. Testing the GEA pipeline on E. coli raw reads demonstrates reproducibility across multiple compute environments and computational usage is optimized on high performance computers.
Adolescent health-risk behaviours in Thailand: patterns from national cross-sectional school surveys conducted in 2008, 2015, and 2021
Authors: Pengpid Supa , Peltzer Karl 
Published: February 2024

Abstract

Background: This study looked at trends in a number of health-risky behaviours among teenagers in Thailand from three separate surveys.
Methods: Data from 12,183 teenagers (mean age: 13.9 years, SD=1.2; age range: 11–16 years) who took part in three cross-sectional national school surveys in Thailand in 2008, 2015, and 2021 were analyzed. A self-administered survey was used to evaluate thirty-three health risk behaviours. By using logistic regression analyses to treat the study year as a categorical variable and adjusting food insecurity and age, the significance of a linear trend was examined.
Results: We found a significant increase in the prevalence of overweight/obesity, inadequate fruit and inadequate vegetables intake, leisure-time sedentary behaviour, physical inactivity, parental tobacco use, physical injury, bullying victimisation, loneliness, not having close friends, sleep problems, ever sex, and suboptimal hand hygiene after toilet use, and a significant decrease in physically attacked. Among boys, a significant increase of inadequate tooth brushing, and suboptimal hand hygiene (not always using soap to wash hands), and a decrease in smoking quit attempts, participation in physical fights, and number of sexual partners, and among females, a decrease in non-condom use was found. Furthermore, among girls, a significant increase in the prevalence of current tobacco use (cigarettes and other), current alcohol use, lifetime drunkenness, trouble from alcohol use, lifetime drug use, suicidal ideation and plan was found.
Conclusion: Overall, from 2008 to 2021, there was a decrease in four health risk behaviours among boys and/or girls, while among boys there was an increase in fourteen health risk behaviours and among girls twenty health risk behaviours. In Thailand, school health programmes for teenagers are recommended.
Analysis of ergot alkaloid gene expression and ergine levels in different parts of Ipomoea asarifolia
Authors: Olaranont Yanisa , Stewart Alyssa B. , Songnuan Wisuwat , Traiperm Paweena 
Published: February 2024

Abstract
Ergot alkaloids are renowned for their pharmacological significance and were historically attributed to fungal symbioses with cereal crops and grasses. Recent research uncovered a symbiotic relationship between the fungus Periglandula ipomoea and Ipomoea asarifolia(Convolvulaceae), revealing a new source for ergot alkaloid synthesis. While past studies have emphasized the storage of both the fungus and alkaloids in leaves and seeds, recent work has found they also occur in other plant parts. This study aimed to (1) examine expression of the dmaW gene, which plays a crucial role in ergot alkaloid biosynthesis, and (2) quantify ergot alkaloid levels across various organs and growth stages of I. asarifolia. Our findings revealed the highest levels of dmaW gene expression in young seeds and young leaves, whereas the highest ergine concentrations were found in mature leaves followed by young leaves. In light of previous studies, we propose three hypotheses to reconcile these conflicting results: (1) the possibility of an inefficient ergot alkaloid biosynthesis pathway, (2) the potential for a complex pathway involving different biosynthesis genes, and (3) the existence of an ergot alkaloid translocation system within the plant. Furthermore, ergine and ergot alkaloid biosynthesis gene expression were detected in stems, roots, and flowers, indicating that ergot alkaloids are produced and accumulated in all studied parts of I. asarifolia, rather than being solely confined to the leaves and seeds, as previously reported.
Graphene-Induced Enhanced Supercapacitor Properties of V2O5-GNPs Nanocomposites for Energy Storage Devices
Authors: Oneeb Muhammad , Iqbal Javed , Mumtaz Asifa , Ullah Qudrat , Ibrar Saba , khan Ahmad H. , Noman M 
Published: February 2024

Abstract
Metal oxides due to high specific capacitances are worthy for electrode material, yielding high energy and power-delivering capacities. Among them, Vanadium pentoxide (V2O5) is a very novel and economical electrode material for supercapacitors using alkaline aqueous electrolytes. In this work, V2O5 and Graphene (GNPs) nanocomposites have been synthesized to improve the conductivity, electrode porosity, and electrode surface area of V2O5. V2O5 nanorods were fabricated using a simple and flexible Sol-gel method, whereas V2O5/Graphene (GNPs) nanocomposites were prepared using an ex-situ approach. Structural analysis of nanocomposites has been performed through XRD, SEM, EDX, EDS, and FTIR. V2O5 nanorods distributed on GNPs substrates showed excellent results as an electrode material. In particular, the nanocomposites (V2O5)0.50 (GNPs)0.50 maintained 96.3% of the initial capacitance over 1350 cycles. High specific capacitance (990 F/g at 5 mV/s from CV, 800 F/g at 2 A/g from GCD), and low ohmic resistance of 0.44 Ω were achieved in 2M NaOH electrolyte. Additionally, these nanocomposites have excellent energy density (27.7 W-hr Kg− 1) at a power density of (1800 W Kg− 1) using a potential window of (0-0.5) V, which is higher than the most previously reported work on V2O5 for supercapacitor.
Impact of prior SARS-CoV-2 infection on postoperative recovery in patients with hepatocellular carcinoma resection
Authors: Fang Dan , Gan Biling , Wu Lei , Guo Chulin , Chen Zhihong , Zhou Shunan , Wu Fan , Xu Lianqun , Chen Zhenrong , Shi Ning , Jin Hao-Sheng 
Published: February 2024

Abstract

BACKGROUND
The impact of prior SARS-CoV-2 infection on postoperative recovery of patients who underwent liver resection for hepatocellular carcinoma (HCC) remains uncertain given the lack of sufficient evidence.
AIM
To investigate the impact of prior SARS-CoV-2 infection on postoperative recovery of patients who underwent liver resection for hepatocellular carcinoma (HCC).
METHODS
Patients who were pathologically diagnosed with HCC and underwent elective partial hepatectomy in Guangdong Provincial People’s Hospital between January 2022 and April 2023 were enrolled in this retrospective cohort study. The patients were divided into two groups based on their history of SARS-CoV-2 infection. Rehabilitation parameters, including postoperative liver function, incidence of complications, and hospitalization expenses, were compared between the two groups. Propensity score matching (PSM) was performed to reduce confounding bias.
RESULTS
We included 172 patients (58 with and 114 without prior SARS-CoV-2 infection) who underwent liver resection for HCC. No significant differences in the rehabilitation parameters were observed between the two groups. After PSM, 58 patients were selected from each group to form the new comparative groups. Similar results were obtained within the population after PSM.
CONCLUSION
Prior SARS-CoV-2 infection does not appear to affect postoperative rehabilitation, including liver function, postoperative complications, or hospitalization expenses among patients with HCC after elective partial hepatectomy.
Variable parameter Uzawa method for solving the indefinite least squares problem
Authors: Meng Lingsheng , Xin Kailiang , Li Jun 
Published: February 2024

Abstract

In this paper, the variable parameter Uzawa method is presented to solve the indefinite least squares problem. The proposed iterative method is unconditionally convergent, and its iterative algorithm and parameter designing are simple and efficient. Numerical experiments show that the variable parameter Uzawa method is superior to the USSOR method \cite{17} and the splitting-based randomized iterative method \cite{21}.
Evaluation of atmospheric conditions at a quasi-national park adjacent to the downtown of a highly industrialized Japanese city
Authors: Abe Momoko , Oniwa Sho , Imazu Hayato , Tanaka Tetsuhiro , Aikawa Masahide 
Published: February 2024

Abstract

The atmospheric condition at the quasi-national park adjacent to the downtown of a highly industrialized city was evaluated based on three-site observations (quasi-national park, downtown, and suburbs). The concentrations of NOx, NO, NO2, O3, SO2, and NH3 were determined. The NOx and NO2 concentrations at the quasi-national park were lower and higher than those downtown and in the suburbs, respectively. The O3 concentration at the quasi-national park was higher than that downtown and equivalent to that in the suburbs, indicating that the impact of O3 air pollution on plants and the forest ecosystem is potentially more severe at the quasi-national park than downtown. Potential ozone (PO), defined as \(\text{P}\text{O}={\text{O}}_{3}+{\text{N}\text{O}}_{2}-0.1\times \text{N}\text{O}\text{x}\), showed no statistically significant difference (p<0.05) among the three sites, indicating that the nitric oxide titration operated and controlled the O3 concentration across the entire city. The definite difference in the level among the three sites in the SO2 concentration strongly implied the large contribution of sulfur supply from stationary emission sources and ships located along the shoreline. Fog events at the quasi-national park could be attributed to the determination of the NH3 concentration at the quasi-national park, i.e., the effective scavenging of NH3 from the ambient air by fog water.
Carbon–Nitrogen Transmutation in Polycyclic Arenol Skeletons to Access N-Heteroarenes
Authors: Wei Hao 
Published: February 2024

Abstract

Developing skeletal editing tools is not a trivial task, and realizing the corresponding single-atom transmutation in a ring system without altering the ring size is even more challenging. Here, we introduce a skeletal editing strategy that enables polycyclic arenols, a highly prevalent motif in bioactive molecules, to be readily converted into N-heteroarenes through carbon–nitrogen transmutation. The reaction features selective nitrogen insertion into the C–C bond of the arenol frameworks by azidative dearomatization and aryl migration, followed by ring opening and re-cyclization of N,O-hemiketal to achieve carbon-to-nitrogen transmutation in the aromatic framework of the arenol. Using widely available arenols as N-heteroarene precursors, this alternative approach allowed the streamlined assembly of complex polycyclic (hetero)aromatics with broad functional group tolerance. This study further highlights the potential for complex skeletal editing sequences through combinations with other single-atom skeletal editing methods, providing an alternative for the development of N-heteroarenes and demonstrating significant potential in materials chemistry.
Connect, Collaborate and Tailor: A model of community engagement through infographic design during the COVID-19 pandemic
Authors: Vernon-Wilson Elizabeth , Tetui Moses , DeMarco Mathew , Grindrod Kelly , Waite Nancy M. 
Published: February 2024

Abstract

Background
Across the globe, racial and ethnic minorities have been disproportionately affected by COVID-19 with increased risk of infection and burden from disease. Vaccine hesitancy has contributed to variation in vaccine uptake and compromised population-based vaccination programs in many countries. Connect, Collaborate and Tailor (CCT) is a Public Health Agency Canada funded project to connect public health and healthcare professionals with underserved communities in order to create culturally adapted communication about COVID-19 vaccines. This paper describes the process and outcomes of this community engagement model that identified information gaps and created tailored tools to address misinformation and improve vaccine acceptance.
Methods
Semi-structured interviews with CCT participants were undertaken to evaluate the effectiveness of CCT and explore CCT members’ experiences of collaboration. Thematic analysis was used to produce representative themes.
Results
Analysis of interviews (n = 14) revealed that shared purpose and urgency in responding to the COVID-19 pandemic motivated co-operation between stakeholders. Acknowledgement of past harm, present health, and impact of social inequities on public service access was an essential first step in establishing trust. Creating safe spaces for open dialogue led to successful, iterative cycles of consultation and feedback between team members; a process that not only helped create tailored communication tools but also deepened engagement and collaboration. Over time, the infographic material development was increasingly directed by community representatives’ commentary on their group’s real-time needs and communication preferences. This feedback noticeably guided the choice, style, and presentation of infographic content while also directing dissemination strategies and vaccine confidence building activities.
Conclusions
The CCT process to create COVID-19 vaccine communication materials led to evolving co-operation between groups who had not routinely worked together before and strong community engagement as a key driver of change. Ensuring a respectful environment for open dialogue and visibly using feedback to create information products provided a foundation for building relationships. Finally, our data indicate participants sought reinforcement of close cooperative ties and continued investment in shared responsibility for community partnership-based public health.
Comparison of Infectious Complications with BCMA-directed Therapies in Multiple Myeloma
Authors: Lesokhin Alexander , Nath Karthik , Shekarkhand Tala , Nemirovsky David , Derkach Andriy , Costa Bruno Almeida , Nishimura Noriko , Farzana Tasmin , Rueda Colin , Chung David , Landau Heather , Lahoud Oscar , Scordo Michael , Shah Gunjan , Hassoun Hani , Maclachlan Kylee , Korde Neha , Shah Urvi , Tan Carlyn Rose , Hultcrantz Malin , Giralt Sergio , Usmani Saad , Shahid Zainab , Mailankody Sham 
Published: February 2024

Abstract

B-cell-maturation-antigen (BCMA)-directed therapies are highly active for multiple myeloma, but infections are emerging as a major challenge. In this retrospective, single-center analysis we evaluated infectious complications after BCMA-targeted chimeric-antigen-receptor T-cell therapy (CAR-T), bispecific-antibodies (BsAb) and antibody-drug-conjugates (ADC). The primary endpoint was severe (grade ≥ 3) infection incidence. Amongst 256 patients, 92 received CAR-T, 55 BsAb and 109 ADC. The incidence of severe infections was higher with BsAb (40%) than CAR-T (26%) or ADC (8%), including grade 5 infections (7% vs 0% vs 0%, respectively). Comparing T-cell redirecting therapies, the incidence rate of severe infections was significantly lower with CAR-T compared to BsAb at 1-year (incidence-rate-ratio [IRR] = 0.43, 95%CI 0.25–0.76, P = 0.004). During periods of treatment-emergent hypogammaglobulinemia, BsAb recipients had higher infection rates (IRR:2.27, 1.31–3.98, P = 0.004) and time to severe infection (HR 2.04, 1.05–3.96, P = 0.036) than their CAR-T counterparts. During periods of non-neutropenia, CAR-T recipients had a lower risk (HR 0.44, 95%CI 0.21–0.93, P = 0.032) and incidence rate (IRR:0.32, 95% 0.17–0.59, P < 0.001) of severe infections than BsAb. In conclusion, we observed an overall higher and more persistent risk of severe infections with BsAb. Our results also suggest a higher infection risk during periods of hypogammaglobulinemia with BsAb, and with neutropenia in CAR-T recipients.
Content and Tissue Expression of Collagen I, Collagen Iv, and Laminin in the Extracellular Matrix in Patients With Prostate Adenocarcinoma
Authors: Góes Igor Arantes , Pereira Maria Roberta Martins , Crotti Enrico , Pereira Geovanna Paciulli , Yoshitani Mateus Magami , Castro Marcos Antonio Santanna , Pereira Jose Aires , Martinez Carlos Augusto Real 
Published: February 2024

Abstract

Prostate cancer is one of the most common neoplasm in the male population. It is not known why some tumors become more aggressive than others. Although most studies show changes in the expression of cell adhesion molecules and the extracellular matrix correlated with the Gleason score, no study has objectively measured the tissue content of these molecules. This study aims to measure the content and tissue expression of collagen type I and IV and laminin in the extracellular matrix of patients with prostate adenocarcinoma and correlate these findings with the Gleason score and clinical characteristics. Forty-one patients who underwent radical prostate surgery at the Urology Department of a reference Hospital in Brazil between January 2015 and December 2020 were studied. The tissue protein content was estimated under light microscopy at a final magnification of 200×. The mean collagen I score in prostate adenocarcinoma tissue samples was 7.16 ± 1.03. The mean type IV collagen score was 3.44 ± 0.61. The mean laminin score was 5.19 ± 0.79. The total Gleason score was correlated with both collagen and laminin. All the correlations were negative, which shows that the higher the collagen/laminin expression was, the lower the total Gleason score. The total Gleason score is correlated with both collagen and laminin expression in prostate neoplasms. The correlations are all negative, which shows that the higher the collagen and laminin values are, the lower the total Gleason score.
Influence of the near roadsoil contamination on the germination and biochemical factors of two species in the region of Sfax (Tunisia)
Authors: Mbadra Chaker , gargouri kamel , mbarek hadda ben , trabelsi lina , Ncube Bhekumtheto , chaabouni semia ellouz 
Published: February 2024

Abstract
In this work we highlight the contamination of three soils in the Sfax region by heavy metals and polycyclic aromatic hydrocarbons and the impact of this contamination in the germination and biochemical factors of two selected species Lycopersicum esculentum and Cucumis sativus. The use of contamination index showed a moderate soil contamination by Zn and Pb up to 50m from gremda road, up to 10m from Manzel Chaker road and 3m from Tunis road. In contrast, no site was contaminated by Cu and Cr. The highest levels of hydrocarbon aromatique polycyclic are recorded in the vicinity of Manzel Chaker soil. On the other hand, the physico-chemical characteristic of studied soils affect the speciation of metals and hydrocarbon. We noted that the metal contamination of gremda soil and the hydrocarbon contamination of Manzel Chaker soil affected the cucumber germination less than tomato germination. The use of germination tests for the two selected species highlighted the capacity of cucumber to resist to both types of pollutants. This resistance is manifested by the slight modification of chlorophyll, proline and soluble sugars contents expressed by the cucumber in polluted soils are less than those expressed by the tomato. An increase in catalase and ascorbate peroxidase activity in tomato plants was observed in vicinity of Gremda road but for cucumber, the levels of these antioxydants enzymes are higher than those recorded in tomato leaves which leads us to the use of cucumber in the phytoremediation of polluted soils near roads in the Sfax region.
Incidence, risk factors and impact on transplant outcomes of cytokine release syndrome after infusion of haploidentical stem cells with anti-thymocyte globulin
Authors: Wang Yu , Zheng Feng-Mei , Kong Jun , Jingzhi Wang , zhidong wang , Wang Fengr-Rong , Han Tingting , Fu Haixia , han wei , Zhang Yuan-Yuan , Yan Chen-Hua , Chen Huan , Chen Yao , Chen Yuhong , Mo Xiao-Dong , Lv Meng , Sun Yuqian , Yifei Cheng , Xu Lan-Ping , Zhang Xiao-hui , Liu Kaiyan , Huang Xiaojun 
Published: February 2024

Abstract
Cytokine release syndrome (CRS) after stem cell infusion in anti-thymocyte globulin (ATG)-based haploidentical (haplo)-hematopoietic stem cell transplantation (SCT) is unclear. We reviewed charts of patients who underwent haplo-SCT between January 2020 and December 2020 and graded CRS. A total of 259 were enrolled in the study. CRS occurred in 103/259 (39.8%) of the recipients, including 83 (80.6%) cases of grade 1 CRS and 20 (19.4%) cases of grade 2 CRS. Severe CRS (grades 3–5) was not observed. Fever was the most common manifestation (89.3%), and all of them occurred only after peripheral blood stem cells (PBSC) infusion. In multivariable analysis, recipients age older than 55 years (OR 2.486(1.124–5.496), p = 0.024), higher CRP during conditioning (OR 3.011 (95%CI, 1.766–5.134), p < 0.001)), and received PBSC as sole stem cell source (OR 2.478 487 (95%CI, 1.077-5.700), p = 0.033) could predict the development of CRS. The 3-year OS was comparable with 80% (95%CI, 61–97) for grade 2 CRS, and 85% (95%CI, 80–90) for grade 0–1 CRS (p = 0.288). GRFS in two groups were 69% (95%CI, 49–90) and 69% (95%CI, 63–75), respectively (p = 0.653). Our results suggest that CRS was common in ATG-based haplo-SCT and did not affect survival.