bluuebunny/crossref_metadata_2025_split huggingface dataset:
Rotational X‐ray coronary angiography
Authors: Raman Subha V. , Morford Ronald , Neff Matthew , Attar Talal T. , Kukielka Gilbert , Magorien Raymond D. , Bush Charles A. 
Published: September 2004

AbstractWe designed and implemented a digital flat‐panel‐based rotational X‐ray coronary angiography technique hypothesizing that luminal disease could be identified with less radiation exposure and contrast usage compared to conventional angiography. Individuals scheduled for diagnostic coronary angiography were prospectively enrolled. In addition to conventional acquisitions in standard planes, subjects underwent one additional left coronary artery (LCA) or right coronary artery (RCA) rotational (spin) acquisition using a predefined trajectory. Radiation exposure and contrast volume were recorded for each run. Seventy‐five subjects were enrolled. When compared with standard five‐view cine acquisition, LCA spin angiography with one cranial and one caudal run resulted in 34.38% ± 13.65% less radiation, 18.98% ± 4.97% less contrast, and comparable assessment of stenosis severity. One spin acquisition compared with three standard cine acquisitions for RCA angiography resulted in 59.31% ± 29.07% lower radiation, no significant change in contrast, and comparable assessment of stenosis severity. Rotational X‐ray coronary angiography provides comparable visualization of coronary anatomy compared with traditional nonrotational coronary angiography with significantly less radiation exposure and contrast volume. Catheter Cardiovasc Interv 2004;63:201–207. © 2004 Wiley‐Liss, Inc.
Treatment of slow/no‐reflow phenomenon with intracoronary nitroprusside injection in primary coronary intervention for acute myocardial infarction
Authors: Wang Huang‐Joe , Lo Ping‐Hang , Lin Jen‐Jyh , Lee Han , Hung Jui‐Sung 
Published: September 2004

AbstractSlow/no‐reflow phenomenon is a serious problem complicating primary percutaneous coronary intervention (PCI) for acute myocardial infarction (AMI) and is associated with a poor prognosis. From January 2002 to November 2002, 11 of the 70 consecutive patients with ST elevation AMI who were subjected to primary PCI using balloon angioplasty and/or stenting developed slow/no‐reflow phenomenon (TIMI 1 flow in 2, TIMI 2 in 8, and TIMI 2.5 in 1). They were 10 men and 1 woman, aged 64 ± 11 years (range, 46–81). The culprit vessels were six in the left anterior descending coronary artery, three in the right coronary artery, one in the left circumflex coronary artery, and one in saphenous vein graft. Multiple bolus doses (100 μg) of nitroprusside were injected into the index artery through the guiding catheter using a 3 ml syringe until the TIMI flow grade improved by at least one grade or the systolic pressure decline below 80 mm Hg (one patient). The total drug dose varied from 100 to 700 μg. Following the drug treatment, angiographic TIMI flow grade improved by at least one grade in 9 (82%) of the 11 patients (P = 0.007). The TIMI frame counts significantly decreased from 36 ± 17 frame counts to 16 ± 11 frame counts (P = 0.012). All patients were discharged without major adverse cardiovascular events. Intracoronary bolus injection of nitroprusside using a 3 ml syringe appears to be a feasible, safe, and effective technique for the management of slow/no‐reflow phenomenon complicating primary PCI. Catheter Cardiovasc Interv 2004;63:171–176. © 2004 Wiley‐Liss, Inc.
Critical stenosis of aortic and mitral valves after mediastinal irradiation
Authors: Adabag A. Selcuk , Dykoski Richard , Ward Herbert , Anand Inder S. 
Published: September 2004

AbstractRadiotherapy is used widely in cancer treatment. Mediastinal irradiation is associated with valvular regurgitation; however, stenosis is rare. We present a patient with critical aortic and mitral valve stenosis after mediastinal irradiation and discuss the natural history, treatment, and prognosis of radiation‐associated valvular heart disease. Catheter Cardiovasc Interv 2004;63:247–250. © 2004 Wiley‐Liss, Inc.
Percutaneous coronary intervention or bypass surgery in multivessel disease? A tailored approach based on coronary pressure measurement
Authors: Botman Kees‐Joost , Pijls Nico H.J. , Bech Jan Willem , Aarnoudse Wilbert , Peels Kathinka , van Straten Bart , Penn Olaf , Michels H. Rolf , Bonnier Hans , Koolen Jacques J. 
Published: September 2004

AbstractThe optimal revascularization strategy, percutaneous coronary intervention (PCI) or coronary artery bypass graft surgery (CABG), for patients with multivessel coronary artery disease (MVD) remains controversial. The aim of the present study was to compare the long‐term outcomes after selective PCI of only hemodynamically significant lesions (fractional flow reserve, or FFR < 0.75) to CABG of all stenoses in patients with MVD. In 150 patients with MVD referred for CABG, FFR was determined in 381 coronary arteries considered for bypass grafting. If the FFR was less than 0.75 in three vessels or in two vessels including the proximal left anterior descending (LAD) artery, CABG was performed (CABG group). If only one or two vessels were physiologically significant (not including the proximal LAD), PCI of those lesions was performed (PCI group). Of the 150 patients, 87 fulfilled the criteria for CABG and 63 for PCI. There were no significant differences in the angiographic or other baseline characteristics between the two groups. At 2‐year follow‐up, no differences were seen in adverse events, including repeat revascularization (event‐free survival 74% in the CABG group and 72% in the PCI group). A similar number of patients were free from angina (84% in the CABG group and 82% in the PCI group). Importantly, the results in both groups were as good as the surgical groups in previous studies comparing PCI and CABG in MVD. In patients with multivessel disease, PCI in those with one or two hemodynamically significant lesions as identified by an FFR < 0.75 yields a similar favorable outcome as CABG in those with three or more culprit lesions despite a similar angiographic extent of disease. Catheter Cardiovasc Interv 2004;63:184–191. © 2004 Wiley‐Liss, Inc.
Alcohol septal ablation for hypertrophic obstructive cardiomyopathy: Lower alcohol dose reduces size of infarction and has comparable hemodynamic and clinical outcome
Authors: Veselka Josef , Procházková Šárka , Duchoňová Radka , Bolomová‐Homolová Ingrid , Páleníčková Jana , Tesař David , Červinka Pavel , Honěk Tomáš 
Published: September 2004

AbstractPatients with highly symptomatic hypertrophic obstructive cardiomyopathy (HOCM) are considered to be good candidates for percutaneous transluminal septal myocardial ablation (PTSMA). However, there is ongoing discussion regarding the optimal dose of alcohol injected into target septal artery and the impact of infarct sizes on the clinical and hemodynamic outcome. Thirty‐four patients with symptomatic HOCM receiving maximum medical therapy were consecutively enrolled. Patients were randomized in a 1:1 ratio into one of the two arms according to dose of injected alcohol during echocardiography‐guided PTSMA procedure. Clinical, electrocardiographic, and echocardiographic evaluation were performed 6 months after the procedure in all the patients. Both groups of patients matched in all clinical and echocardiographic data. The dose of alcohol injected was 1.6 ± 0.4 and 3.4 ± 0.9 (P < 0.001) with subsequent peak of CK‐MB 1.9 and 3.2 μkat/L (P < 0.05) in group A and B, respectively. There was a correlation between amount of injected alcohol and the peak of CK‐MB (r = 0.58; P < 0.01), whereas no significant relationship (r = 0.16; P = NS) was documented between the peak of CK‐MB and left ventricular outflow gradient at follow‐up. At 6‐month follow‐up, both groups of patients were not significantly different with regard to symptoms or electrocardiographic and echocardiographic findings. In conclusion, this study suggests that the low dose (1– 2 ml) of alcohol injected into target septal branch reduces size of necrosis. Moreover, the low dose is probably as safe and efficacious as usually used doses (2–4 ml). Catheter Cardiovasc Interv 2004;63:231–235. © 2004 Wiley‐Liss, Inc.
Charge Order and Tilt Modulation in Multiferroic KxMIIxMIII1‐x F3 (0.4 < x < 0.6) Transition Metal Fluorides with Tetragonal Tungsten Bronze Structure.
Authors: Fabbrici Simone , Montanari Erica , Righi Lara , Calestani Gianluca , Migliori Andrea 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Compounds from Tellurocyanide Rhenium Cluster Anions and 3d‐Transition Metal Cations Coordinated with Ethylenediamine.
Authors: Brylev Konstantin A. , Mironov Yuri V. , Naumov Nikolai G. , Fedorov Vladimir E. , Ibers James A. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Organic Reactions in Ionic Liquids: An Efficient Method for Selective S‐Alkylation of 2‐Mercaptobenzothia(xa)zole with Alkyl Halides.
Authors: Hu Yi , Chen Zhen‐Chu , Le Zhang‐Gao , Zheng Qin‐Guo 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Immediate and Efficient Oxidative Deprotection of Dithioacetals to Carbonyl Compounds by Zinc Dichromate Trihydrate (ZnCr2O7×3H2O).
Authors: Firouzabadi Habib , Iranpoor Nasser , Hassani Hassan , Sobhani Sara 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Highly Selective Isomerization of N‐Allylamides and N‐Allylamines.
Authors: Krompiec Stanislaw , Pigulla Mariola , Krompiec Michal , Baj Stefan , Mrowiec‐Bialon Julita , Kasperczyk Janusz 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Stereoselective Preparation of (Z)‐3‐Perfluoroalkyl‐3‐magnesiated Enoates by an Iodine—Magnesium Exchange Reaction.
Authors: Thibonnet Jerome , Duchene Alain , Parrain Jean‐Luc , Abarbri Mohamed 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reactions of TFDA with Ketones. Synthesis of Difluoromethyl 2,2‐Difluorocyclopropyl Ethers.
Authors: Cai Xiaohong , Zhai Yian , Ghiviriga Ion , Abboud Khalil A. , Dolbier William R. Jr. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Intramolecular Pauson—Khand Reaction of 3‐Alkynyl‐1‐alkylidenecycles: A Convenient Synthesis of [5.n.1.01,5] Tricyclic Compounds.
Authors: Ishizaki Miyuki , Masamoto Mina , Hoshino Osamu , Nishitani Kiyoshi , Hara Hiroshi 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Sonogashira Cross‐Couplings of Ynamides. Syntheses of Urethane‐ and Sulfonamide‐Terminated Conjugated Phenylacetylenic Systems.
Authors: Tracey Michael R. , Zhang Yanshi , Frederick Michael O. , Mulder Jason A. , Hsung Richard P. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
One‐Pot Synthesis of Nitriles from Aldehydes and Hydroxylamine Hydrochloride over Silica Gel, Montmorillonites K‐10, and KSF Catalysts in Dry Media under Microwave Irradiation.
Authors: Dewan Sharwan K. , Singh Ravinder , Kumar Anil 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New Precatalyst for the Suzuki Reaction — A Pyridyl‐bridged Dinuclear Palladium Complex as a Source of Mono‐ligated Palladium(0).
Authors: Beeby Andrew , Bettington Syliva , Fairlamb Ian J. S. , Goeta Andres E. , Kapdi Anant R. , Niemelae Elina H. , Thompson Amber L. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Chemistry of Polyhalogenated Nitrobutadienes. Part 1. A New Synthesis of Perfunctionalized 3‐Amino‐4‐nitrothiophenes.
Authors: Zapol'skii Viktor A. , Namyslo Jan C. , Adam Arnold E. W. , Kaufmann Dieter E. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Use of Highly Reactive, Versatile and Air‐Stable Palladium—Phosphinous Acid Complex [(t‐Bu)2P(OH)]2PdCl2 (POPd) as a Catalyst for the Optimized Suzuki—Miyaura Cross‐Coupling of Less Reactive Heteroaryl Chlorides and Arylboronic Acids.
Authors: Khanapure Subhash P. , Garvey David S. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
3,4‐Dihydroquinazoline Derivatives as Novel Selective T‐Type Ca2+ Channel Blockers.
Authors: Lee Yong Sup , Lee Bum Hoon , Park Seong Jun , Kang Soon Bang , Rhim Hyewhon , Park Jin‐Yong , Lee Jung‐Ha , Jeong Seong‐Woo , Lee Jae Yeol 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Iodo‐Cyclization of N‐Homoallyl Thioamides Leading to 2,4‐Diaryl‐5,6‐dihydro‐4H‐1,3‐thiazines.
Authors: Murai Toshiaki , Niwa Hisayuki , Kimura Tsutomu , Shibahara Fumitoshi 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Highly Active Taxoids from 9β‐Dihydrobaccatin‐9,10‐acetals. Part 5
Authors: Takeda Yasuyuki , Uoto Kouichi , Iwahana Michio , Jimbo Takeshi , Nagata Motoko , Atsumi Ryo , Ono Chiho , Tanaka Noriko , Terasawa Hirofumi , Soga Tsunehiko 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Ceric Ammonium Nitrate (CAN) Catalyzed Baeyer—Villiger Oxidation of Carbonyl Compounds, Specially 20‐Oxosteroids.
Authors: Goswami Papori , Hazarika Saroj , Das Archana M. , Chowdhury Pritish 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Mild, Efficient and α‐Selective Glycosidation by Using Potassium Dodecatungstocobaltate Trihydrate as Catalyst.
Authors: Rafiee Ezzat , Tangestaninejad Shahram , Habibi Mohammad H. , Mirkhani Valiollah 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of α,ω‐Diazidoalditol Derivatives via Both bis‐ and tris‐Cyclic Sulfites and Peracetylated α,ω‐Dibromoalditols as Bielectrophilic Intermediates.
Authors: Glacon Virginie , Benazza Mohammed , El Anzi Aniss , Beaupere Daniel , Demailly Gilles 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stereoselective Conjugate Addition of Benzyl Phenylsulfonyl Carbanions to Enoates Derived from D‐Mannitol.
Authors: Ferreira Andre R. G. , de A. Vilela Guilherme V. M. , Amorim Mauro B. , Perry Katia P. , da Silva Antonio J. R. , Dias Ayres G. , Costa Paulo R. R. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A New General Access to Either Type of Securinega Alkaloids: Synthesis of Securinine (II) and (‐)‐Allonorsecurinine (XII).
Authors: Alibes Ramon , Ballbe Marta , Busque Felix , de March Pedro , Elias Laia , Figueredo Marta , Font Josep 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Chemoenzymatic Syntheses of Homo‐ and Heterodimers of AZT and d4T, and Evaluation of Their anti‐HIV Activity.
Authors: Taourirte M. , Mohamed L. Ait , Rochdi A. , Vasseur J.‐J. , Fernandez S. , Ferrero M. , Gotor V. , Pannecouque C. , De Clercq E. , Lazrek H. B. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Recent Developments in Marine Indole Alkaloid Synthesis
Authors: Nakagawa Masako , Nagata Toshiaki , Ono Koji , Uchida Hideharu , Watanabe Takeshi , Hatakeyama Keisuke , Akiba Masakatsu , Fuwa Mihoko , Arisawa Mitsuhiro , Nishida Atsushi 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
From 1,3‐Diphosphetane‐2,4‐diyls to Cyclic Anions and Cations
Authors: Sebastian M. , Schmidt O. , Fuchs A. , Nieger M. , Szieberth D. , Nyulaszi L. , Niecke E. 
Published: September 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Effects on instruments of the World Health Organization–recommended protocols for decontamination after possible exposure to transmissible spongiform encephalopathy–contaminated tissue
Authors: Brown Stanley A. , Merritt Katharine , Woods Terry O. , Busick Deanna N. 
Published: September 2004

AbstractIt has been recommended by the World Health Organization (WHO) and Centers for Disease Control and Prevention (CDC) that rigorous decontamination protocols be used on surgical instruments that have been exposed to tissue possibly contaminated with Creutzfeldt–Jakob disease (CJD). This study was designed to examine the effects of these protocols on various types of surgical instruments. The most important conclusions are: (1) autoclaving in 1N NaOH will cause darkening of some instruments; (2) soaking in 1N NaOH at room temperature damages carbon steel but not stainless steel or titanium; (3) soaking in chlorine bleach will badly corrode gold‐plated instruments and will damage some, but not all, stainless‐steel instruments, especially welded and soldered joints. Damage became apparent after the first exposure and therefore long tests are not necessary to establish which instruments will be damaged. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 72B: 186–190, 2005
Poly(lactic‐co‐glycolic acid) microspheres as a potential bulking agent for urological injection therapy: Preliminary results
Authors: Cho Eui Ri , Kang Sun‐Woong , Kim Byung‐Soo 
Published: September 2004

AbstractInjection of bulking substances has been introduced as a new therapy to treat urinary incontinence and vesicoureteral reflux. Currently available bulking substances for the injection therapies include liquid or particulated silicone, collagen gel, and polytetrafluoroethylene paste. However, these materials have shown shortcomings such as inflammation, rapid volume decrease, and particle migration to distant organs. In the present study, we evaluated poly(lactic‐co‐glycolic acid) (PLGA) microspheres as a potential injectable bulking agent for the injection therapies. PLGA microspheres (52 μm in average diameter) were injectable through various gauges of needles, as the injected microspheres showed no tendency to obstruct the needles and microsphere size exclusion was not observed upon injection through the needles. After injection of PLGA microspheres into the subcutaneous dorsum of mice, inflammation, new tissue volume change, and microsphere migration were examined. Host cells from the surrounding tissues migrated to the implanted microspheres and formed new hybrid tissue structures. The volume of the newly generated tissues was maintained approximately constant for 7 weeks. Histological analyses showed no evidence of migration of the implanted microspheres to the distant organs. In summary, PLGA microspheres were injectable and able to induce a new hybrid tissue formation without initial volume decrease or particle migration. These preliminary results suggest that this material may be a potentially useful bulking agent for urological injection therapies. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 72B: 166–172, 2005
Does endotoxin contribute to aseptic loosening of orthopedic implants?
Authors: Greenfield Edward M. , Bi Yanming , Ragab Ashraf A. , Goldberg Victor M. , Nalepka Jennifer L. , Seabold Joscelyn M. 
Published: September 2004

AbstractAseptic loosening of orthopedic implants caused by wear particles is a major clinical problem. This review examines the hypothesis that bacterial endotoxin contributes to aseptic loosening. Clinical findings support this hypothesis: bacterial biofilms exist on many implants from patients with aseptic loosening and antibiotics in bone cement reduce the rate of aseptic loosening. Three approaches were used to demonstrate that adherent endotoxin increases bioactivity of titanium particles. These experiments measured cytokine production and osteoclast differentiation in vitro and murine calvarial osteolysis in vivo. First, removal of >99.9% of the adherent endotoxin from titanium particles significantly ablates their biological activity. Second, adding lipopolysaccharide back to these “endotoxin‐free” particles restores their biological activity. Third, cells or mice that are genetically hyporesponsive to endotoxin are significantly less responsive to titanium particles than are wild‐type controls. Other investigators have confirmed and extended these results to include virtually all orthopedically relevant types of particles, including authentic titanium alloy particles retrieved from patients with loosening. Our recent studies suggest that adherent endotoxin on orthopedic implants may also inhibit initial osseointegration of the implants. Taken together, these studies suggest that bacterial endotoxin may have a significant role in induction of aseptic loosening. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 72B: 179–185, 2005
Analysis of photopolymerization behavior of UDMA/TEGDMA resin mixture and its composite by differential scanning calorimetry
Authors: Tanimoto Yasuhiro , Hayakawa Tohru , Nemoto Kimiya 
Published: September 2004

AbstractThe aim of this study was to investigate the extent of polymerization (Ep) in terms of polymerization rate of UDMA/TEGDMA resin mixtures and its composite resin, by using a differential scanning calorimeter (DSC) technique employing a photopolymerization apparatus. The resin mixtures used in this study consisted of urethane dimethacrylate (UDMA) as a base monomer and triethyleneglycol dimethacrylate (TEGDMA) as a low viscosity monomer. The concentration of TEGDMA in the mixed monomer was varied to 0, 20, 40, 60, 80, and 100 mol %. Additionally, using a base monomer consisting of 60 mol % UDMA and 40 mol % TEGDMA, four kinds of composites with silica filler of 0, 20, 40, 60, and 70 wt %, were prepared in this study. The general reaction profile and Ep values were obtained from the DSC curves. Increasing the concentration of TEGDMA resulted in a decrease in the viscosity of the UDMA/TEGDMA mixture, a delay in the time to maximum polymerization rate, and an increase in the Ep values of the resin mixtures. Furthermore, Ep values decreased with increasing filler content between 0 and 60 wt % but did not decrease further between 60 and 70 wt %. © 2004 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater 72B: 310–315, 2005
Egr‐1 is activated by 17β‐estradiol in MCF‐7 cells by mitogen‐activated protein kinase‐dependent phosphorylation of ELK‐1
Authors: Chen Chien‐Cheng , Lee Wan‐Ru , Safe Stephen 
Published: September 2004

AbstractEarly growth response‐1 (Egr‐1) is an immediate‐early gene induced by E2 in the rodent uterus and breast cancer cells. E2 induces Egr‐1 mRNA and protein levels in MCF‐7 human breast cancer cells and reporter gene activity in cells transfected with pEgr‐1A, a construct containing the −600 to +12 region of the Egr‐1 promoter linked to the firefly luciferase gene. Deletion analysis of the Egr‐1 promoter identified a minimal E2‐responsive region of the promoter that contained serum response element (SRE)3 (−376 to −350) which bound Elk‐1 and serum response factor (SRF) in gel mobility shift assays. Hormone‐responsiveness of Egr‐1 in MCF‐7 cells was specifically inhibited by PD98059, a mitogen‐activated protein kinase kinase inhibitor, but not by LY294002, an inhibitor of phosphatidylinositol‐3‐kinase (PI3‐K). These results contrasted with hormone‐dependent activation of the SRE in the c‐fos promoter, which was inhibited by both PD98059 and LY294002. Differences in activation of the SREs in Egr‐1 and c‐fos were related to promoter sequence, which defines the affinities of Elk‐1 and SRF to their respective binding sites. Thus, Egr‐1, like c‐fos, is activated through non‐genomic (extranuclear) pathways of estrogen action in breast cancer cells. © 2004 Wiley‐Liss, Inc.