bluuebunny/crossref_metadata_2025_split huggingface dataset:
More Widespread use of Ivermectin for the Treatment of COVID-19
Infection could have Saved Many
Authors: Boretti Alberto , Banik Bimal K. 
Published: October 2023

Abstract:
Here we review the available literature for the specific use of Ivermectin against COVID-19 infection. Currently, 204 works have been published presenting the results of ivermectin use for COVID-19. 156 are peer-reviewed, and 96 are comparing treatment and control groups. Ivermectin was adopted for early treatment in all or part of 22 countries (39 including non-government medical organizations). The 96 studies of Ivermectin for COVID-19 were published by 1,030 scientists, reporting the cases of 135,554 patients in 27 countries. These studies show a statistically significant improvement in mortality, ventilation, ICU, hospitalization, recovery, cases, and viral clearance. Specifically, improvements recorded were 85%, 62%, and 43% for prophylaxis, early, and late treatment, with confidence intervals (CI) [77-90%], [51-70%], [28-54%] respectively. A 56% improvement was recorded in the 45 randomized controlled trials (RCTs) with CI [41-68%]. A 51% lower mortality was evidenced from 49 studies with CI [37-61%]. In February 2021, when the war on Ivermectin started in the West, it was clear that this drug had positive effects, working in-vivo/in-vitro, and delivering mostly positive results in clinical trials. More widespread use of Ivermectin could have saved many people, and suppression of this drug in many countries that had very high cumulative fatalities per million people has been a very unfortunate occurrence for science.
Using Transformer-Based Topic Modeling to Examine Discussions of Delta-8 Tetrahydrocannabinol: Content Analysis
Authors: Smith Brandi Patrice , Hoots Brooke , DePadilla Lara , Roehler Douglas R , Holland Kristin M , Bowen Daniel A , Sumner Steven A 
Published: October 2023

Background
Delta-8 tetrahydrocannabinol (THC) is a psychoactive cannabinoid found in small amounts naturally in the cannabis plant; it can also be synthetically produced in larger quantities from hemp-derived cannabidiol. Most states permit the sale of hemp and hemp-derived cannabidiol products; thus, hemp-derived delta-8 THC products have become widely available in many state hemp marketplaces, even where delta-9 THC, the most prominently occurring THC isomer in cannabis, is not currently legal. Health concerns related to the processing of delta-8 THC products and their psychoactive effects remain understudied.

Objective
The goal of this study is to implement a novel topic modeling approach based on transformers, a state-of-the-art natural language processing architecture, to identify and describe emerging trends and topics of discussion about delta-8 THC from social media discourse, including potential symptoms and adverse health outcomes experienced by people using delta-8 THC products.

Methods
Posts from January 2008 to December 2021 discussing delta-8 THC were isolated from cannabis-related drug forums on Reddit (Reddit Inc), a social media platform that hosts the largest web-based drug forums worldwide. Unsupervised topic modeling with state-of-the-art transformer-based models was used to cluster posts into topics and assign labels describing the kinds of issues being discussed with respect to delta-8 THC. Results were then validated by human subject matter experts.

Results
There were 41,191 delta-8 THC posts identified and 81 topics isolated, the most prevalent being (1) discussion of specific brands or products, (2) comparison of delta-8 THC to other hemp-derived cannabinoids, and (3) safety warnings. About 5% (n=1220) of posts from the resulting topics included content discussing health-related symptoms such as anxiety, sleep disturbance, and breathing problems. Until 2020, Reddit posts contained fewer than 10 mentions of delta-8-THC for every 100,000 cannabis posts annually. However, in 2020, these rates increased by 13 times the 2019 rate (to 99.2 mentions per 100,000 cannabis posts) and continued to increase into 2021 (349.5 mentions per 100,000 cannabis posts).

Conclusions
Our study provides insights into emerging public health concerns around delta-8 THC, a novel substance about which little is known. Furthermore, we demonstrate the use of transformer-based unsupervised learning approaches to derive intelligible topics from highly unstructured discussions of delta-8 THC, which may help improve the timeliness of identification of emerging health concerns related to new substances.
Formación médica y escenario sociopolítico contingente: experiencia a propósito de un proceso constituyente nacional
Authors: Villalón-Calderón Marcelo Alfredo , Cerda-Thomas Rodrigo Alberto , Romero-Barrientos Aura Constanza 
Published: October 2023

Introducción: El proceso de cambio constitucional chileno propició una instancia de reflexión y discusión desde una perspectiva profesional y ciudadana entre los residentes del Programa de Formación de Médicos Especialistas en Salud Pública (PFMESP) de la Universidad de Chile.
Seminario: Se realizó un seminario sobre este proceso, ideado por los residentes y guiado por el responsable del comité académico del PFMESP, dada la estrecha relación entre los marcos normativos y el quehacer de los médicos especialistas en salud pública (MESP). Las temáticas seleccionadas abarcaron aspectos conceptuales sobre normas constitucionales, su relación con la salud, contenidos específicos de la propuesta de nueva constitución (NC) y perspectivas de futuro. Se dio especial relevancia al establecimiento del diálogo constructivo, evitando la confrontación inorgánica.
Formación médica y contingencia sociopolítica: El seminario puede considerarse como un ejercicio de integración de elementos de pertinencia social en la formación médica, aspecto valorado en los procesos de acreditación de los programas de formación y del rol de la Universidad. Como parte de esta experiencia se espera que emerjan competencias deseables como la responsabilidad social, la ciudadanía profesional y el liderazgo. La formación en el ejercicio de estas supone estimular el pensamiento crítico, que aproxima de forma reflexiva la contingencia sociopolítica a las dimensiones individual y pública de la práctica de la profesión.
Aprendizajes y discusión: Se logró contactar aspectos del escenario social y político contingente con saberes específicos de los MESP. Se pusieron en práctica habilidades de liderazgo, trabajo en equipo y de diálogo profesional interpares. Finalmente, quedan planteadas temáticas y preguntas que cuestionan los modelos de desarrollo de las naciones, la valoración de la vida y salud de sus comunidades y su traducción en diversos cuerpos normativos.
Editorial
Authors: Flores Trejo Fernando Guadalupe 
Published: October 2023

Me resulta muy grato dirigirme a ustedes, los autores y las autoras de artículos jurídicos, a los y las estudiantes de la ciencia jurídica, así como a nuestros asiduos lectores y lectoras de esta Revista del Posgrado en Derecho, ya que serán objeto de publicación, valiosos ensayos jurídicos, así como interesantes entrevistas y una nueva aportación, consistente en la publicación de capítulos de tesis de grado.
Rear Admiral N. Loyall McLaren: The Highest-Ranking CPA in the U.S. Navy
Authors: Jobe Mark E. , Flesher Dale L. 
Published: October 2023

ABSTRACT
From the onset of World War II, America needed men of integrity, ability, and proven leadership to facilitate the wartime economy—the nation turned to CPAs for help. In 1941, the president of the American Institute of Accountants, N. Loyall McLaren, stepped away from his accounting firm and from his Institute presidency to serve in the U.S. Navy where he handled a variety of accounting-related duties. McLaren was a pioneer California CPA, serving as a partner in the largest firm in the Golden State, and had served as president of the California Society of CPAs. He later was a powerful business leader in the San Francisco area; his firm eventually merged with Haskins & Sells. This is the story of Commander (later Rear Admiral; also Army Brigadier General) McLaren and his service to the nation and the profession during World War II and thereafter.
The Effects of Message Quotes on Tax Compliance
Authors: Foy Joseph , Sampath Vijay , DiGabriele James A. , Abbu Haroon 
Published: October 2023

ABSTRACT
This paper examines the effects of regulatory focus and regulatory fit theories on taxpayer compliance when taxpayers are exposed to predetermined quotes by the Internal Revenue Service (IRS) or other tax authority officials. A promotion-oriented regulatory focus is concerned with advancement, growth, and accomplishment, whereas a prevention-oriented regulatory focus is concerned with protection, safety, and responsibility. Using an experimental approach, we find that promotion-oriented (prevention-oriented) individuals are more likely (less likely) than prevention-oriented (promotion-oriented) individuals to self-report income for tax purposes. We also find that (1) promotion-oriented (prevention-oriented) individuals are less (more) likely to self-report income when presented with prevention-focused and neutral quotes as compared to messages with no quotes, and (2) promotion-oriented individuals who read promotion-focused quotes are more likely to self-report income than those reading prevention-focused message quotes. The results suggest theoretical and practical implications for tax compliance.
Modelagem matemática no ensino de números racionais: Uma aplicação prática utilizando dados sobre Resíduos Sólidos Urbanos
Authors: Cunha Everton Carvalhaes , Oliveira Deumara Galdino de 
Published: October 2023

O panorama educacional brasileiro tem se mostrado cada vez menos eficiente, uma vez que permanece em um modelo tradicional fabril. Uma metodologia que tende a quebrar este paradigma é a modelagem no ensino de matemática. Esta metodologia de ensino consiste em utilizar situações reais, ou mais próximas da realidade, para ensinar conceitos matemáticos e, partindo disso, gerar o debate sobre o conteúdo. Um possível objeto para se utilizar nessa metodologia são os Resíduos Sólidos Urbanos, popularmente conhecido como lixo. O lixo está presente na vida de todos os cidadãos, independentemente de sua classe social e cultural. Com isso, juntando a metodologia de modelagem matemática com os dados do lixo, podem-se desenvolver diversos modelos de aulas. O professor precisa ter o conhecimento sobre a modelagem em sala de aula e, além disso, precisa ser consciente quanto ao papel e a responsabilidade do cidadão na sociedade quanto ao tratamento do lixo. A proposta apresentada neste texto é a utilização da modelagem matemática no ensino de números racionais utilizando dados sobre os resíduos sólidos urbanos. Realizando uma atividade em uma turma de sétimo ano do ensino fundamental da instituição de ensino Colégio Betel, em Queimados/RJ, este artigo apresenta possibilidades de como trabalhar com esses dados e aborda um exemplo prático. A atividade, além de contribuir para identificar as dificuldades dos alunos sobre o conteúdo de números racionais, contribuiu para conscientização e reflexão sobre o tema além de consequências inerentes, como saúde pública, problemas sociais, econômicos e ambientais.
Pengembangan Digital Game sebagai Sarana Pembelajaran Matematika untuk Difabel
Authors: Mangowal Remy Giovanny 
Published: October 2023

Abstract—People with disabilities are highly capable human resources as long as proper education are given to them. However, number of researches for disabled people’s education is far behind those for regular people. This presents a great hurdle for educators. To combat this, an unorthodox way with a digital educational game is presented. Said game helps students with disabilities concentrate better than conventional study methods. A survey for the facilities’ educators shows that they agreed that the students are more enthusiastic than usual. Another survey for the students themselves resulted in a overwhelmingly positive welcome, saying it’s more fun than regular classes. This shows that the digital educational game MathBharataV3 shows clear and positive results as a mathematics learning aid for disabled students.
Keywords: game-based learning, disabled students, educational game

Abstrak—Sumber daya manusia dengan difabilitas adalah sumber daya manusia yang memiliki potensi tinggi selama difasilitasi dengan metode pembelajaran yang tepat. Namun, jumlah penelitian bagi metode pembelajaran siswa difabel jauh lebih sedikit daripada penelitian untuk siswa reguler. Tantangan besar untuk pendidik pada bidang ini dapat diselesaikan dengan sebuah metode yang tidak lazim digunakan, yaitu dengan menggunakan game pembelajaran digital. Game tersebut membantu siswa difabel lebih berkonsentrasi dibandingkan dengan metode pembelajaran konvensional. Sebuah survei untuk pendidik fasilitas difabel tersebut menunjukkan para pendidik setuju bahwa siswa difabel menjadi lebih tertarik daripada biasanya. Sebuah survei lain pada siswa difabel menunjukkan hasil yang sangat positif, dengan sangat banyak respon yang mengatakan bahwa game tersebut lebih menarik dari kelas biasanya. Seluruh hasil survei ini menunjukkan bahwa game pembelajaran berbasis digital tersebut memberikan hasil yang jelas dan positif sebagai media pembantu pembelajaran matematika pada siswa difabel.
Kata kunci: pembelajaran berbasis game, siswa difabel, game pembelajaran
Pengaruh Jarak Tanam dan Dosis Pupuk NPK Terhadap Produksi dan Mutu Benih Mentimun (Cucumis sativus L.)
Authors: Amsyari Muhammad Fuad , Rahayu Sri 
Published: October 2023

Cucumber fruit is a fruit that has various benefits in everyday life, including food, medicine, and cosmetics. Cucumber cultivation is still not good enough so that it cannot meet domestic market demand. This study aims to determine the effect of the interaction between spacing treatment and doses of NPK fertilizer on the production and quality of cucumber seeds. This study used a factorial randomized complete block design (RCBD). The first factor was the treatment of spacing with 3 treatment levels and the second factor was the application of NPK fertilizer with 3 treatment levels. Each treatment was repeated 3 times, so there were 27 experimental units. The results of this study are based on the results of the analysis and discussion of the treatment spacing of 40 cm x 60 cm which has a very significant effect on the diameter of the fruit having an average of 7.18 cm, the length of the fruit having an average of 27.24 cm, and the weight of 100 grains having an average an average of 2.29 grams. NPK fertilizer dose treatment of 250 kg/Ha had a very significant effect on the fruit diameter had an average of 7.18 cm, fruit length had an average of
27.24 cm, flowering age had an average of 24.33 HST, number of seeds per fruit has an average of
315.47 grains, seed weight per fruit has an average of 7.37 grams, weight of 100 seeds has an average of 2.29 grams and seed weight per hectare has an average of 159.26 kilograms. The treatment interaction with a spacing of 40 cm x 60 cm and a dose of NPK fertilizer of 250 kg/ha gave the best value for fruit weight, namely 737.87 grams. Furthermore, the observation parameters that show significant or very significant differences are further tested using the DMRT test with a level of 5%.
Pengaruh Previcur-N Pada Perkecambahan Benih Biji Bawang Merah
Authors: Azmi Chotimatul , Rahayu Astiti , Saadah Imas Rita , Wulandari Astri Windia , Sahat Juniarti P , Jayanti Hadis , Susilowati Dwi Ningsih 
Published: October 2023

Seedlings are a challenge for True Shallot Seeds (TSS). Prior to sowing, farmers frequently apply water, warm water, pesticides, or growth regulators. Previcur-N is a fungicide used by farmers. The purpose of this study was to see the effect of Previcur-N on True Shallot Seed (TSS) in the lab. With two factors and four replications, the experiment was conducted using a randomized block design. The first factor is soaking period (1 hour, 2 hours, 3 hours, and 4 hours), and the second factor is Previcur-N doze (0 ml/L, 0.5 ml/L, 1 ml/ L, 1.5 ml/L) with control (non-soaking treatment). Hypocotyl length, germination speed, seedling growth rate, germination percentage, abnormal seedling percentage, and dead seed percentage were all observed. The results indicate that, most Previcur-N treatments lowered hypocotyl length, germination speed, and germination percentage, exceptionally the 1 ml/L for 1 hour treatment. Nevertheless, the Soaking water treatment for 2 hours can increase the germination of TSS seeds
Analisis Faktor Penyebab Rendahnya Bed Occupancy Rate (BOR) di Balai Besar Kesehatan Paru Masyarakat Makassar
Authors: Salim Agus , Rachmawati Ervina , Santi Maya Weka , Muflihatin Indah 
Published: October 2023

Abstrak
Bed Occupancy Rate (BOR) di Balai Besar Kesehatan Paru Masyarakat Makassar dalam 3 tahun terakhir mengalami penurunan pada tahun 2018 64%, tahun 2019 62% dan tahun 2020 52%. BOR merupakan salah satu indikator pelayanan kesehatan yang dapat dipakai untuk mengetahui tinggi rendahnya mutu, tingkat pemanfaatan fasilitas dan efesiensi pelayanan kesehatan. Dampak penurunan BOR menimbulkan penurunan pendapatan ekonomi bagi pihak Rumah Sakit. Tujuan dari penelitian ini adalah untuk menganalisis faktor penyebab rendahnya BOR di Balai Besar Kesehatan Paru Masyarakat Makassar dengan (sumber daya manusia), (sarana dan prasarana), (kedisiplinan pemberi pelayan kesehatan) dan (upaya perbaikan masalah). Penelitian ini menggunakan metode penelitian kualitatif, dengan maksud menggali lebih dalam faktor penyebab rendahnya BOR dengan menggunakan teknik wawancara, observasi, dokumentasi dan brainstorming yang melibatkan 3 informan meliputi HRD, kepala bidang sarana dan prasarana dan kepala bidang keperawatan. Hasil penelitian ini menunjukkan bahwa faktor penyebab rendahnya BOR yaitu kurangnya jumlah sumber daya manusia perawat, fasilitas sarana dan prasaran belum memadai, kedisiplinan pemberi pelayan kesehatan belum konsisten. Adapun upaya solusi yaitu sumber daya manusia perlu ditambah fasilitas sarana dan prasarana segera ditingkatkan dan melengkapi fasilitas sarana dan prasarana yang belum tersedia.
Kata Kunci: Bed Occupancy Rate,Sumber Daya Manusia, Sarana dan Prasaran
The origin, nature and ﬂuid characteristics of the hydrothermal veining crosscutting the Yzerfontein gabbro-diorite, Cape Granite Suite, South Africa
Authors: Wilson S. , Bailie R. , Harris C. , Dunn S. , Silinda V. , Lembede S.N. 
Published: October 2023

Abstract
The maﬁc to felsic rocks at Yzerfontein form part of a composite 535 Ma post-orogenic pluton belonging to the Cape Granite Suite (CGS) of the Pan-African Saldania Belt of southwestern Africa. The pluton ranges from olivine gabbros (mostly at the northern end) to quartz monzonites, with monzonites the most abundant rock type. Minor felsic rocks in the form of quartz microsyenites and monzogranite occur more toward the southern end. The comparatively unaltered gabbro/monzonite has pyroxene δ18O values of 6.4‰, consistent with a mildly crustal-contaminated mantle-derived magma. Published εNd values of -1.9 to -0.3 similarly reﬂect crustal contamination of these maﬁc to intermediate rocks.
The pluton is crosscut by extensive hydrothermal veining. Early quartz veining was followed by the precipitation of pyrite, calcite, tourmaline, jasper, epidote and a ﬁnal stage involving the formation of barren quartz veins. The veins contain low-salinity (3 to 11 wt.% NaCl eq.), three phase (liquid + vapour ± opaques) ﬂuid inclusions with total homogenisation temperatures of 125 to 320°C. The δ18O values of the quartz veins range from 9.8 to 14.7‰ and the ﬂuid inclusion δD values range from -9 to -17‰. These ranges, together with the low salinities, are consistent with a meteoric origin for the vein ﬂuids.
Bulk-rock δ18O values range from 7.3 to 13.3‰ consistent with interaction of near surface ﬂuids at temperatures of &lt;300°C with the magmatic rocks. Open-space ﬁlling textures in quartz veins suggest vein formation in a hydrostatic regime. These, together with ﬂuid inclusion isochores, suggest temperature-pressure conditions of no more than 170 to 300°C at ~0.5 kbar and no more than 1.6 kbar. The mineralised veins represent a shallow, poorly developed and possibly low-grade epithermal system.
The mineralisation is likely related to drawdown of meteoric ﬂuids during sub-solidus cooling of the dominantly intermediate pluton with little to no magmatic ﬂuid inﬂuence. The mineralisation is poorly developed, possibly due to a lack of mixing between different ﬂuid types. The various magmatic rocks, varying from maﬁc through dominantly intermediate to minor felsic, represents a minor mantle-derived maﬁc component of the Cape Granite Suite and likely related to the heat source that gave rise to voluminous crustal melting that generated the granitic magmas of the majority of the CGS.
Impact of Women's Role in Improving Family Welfare in Bantul Yogyakarta District Using the CIBEST Model
Authors: Arminingsih Diah 
Published: October 2023

The GBHN states that women have rights, responsibilities and have the opportunity to fully participate in development. So that as a consequence in the perspective of national interests, women must be involved and involved in solving national problems. Women's empowerment is an indicator of increasing welfare. If women are empowered economically, intellectually and spiritually, it will be very effective for the development of society and the nation. The purpose of this study was to determine the impact of women's role in improving family welfare from an Islamic perspective. The research design uses mixed methods through two stages which are carried out at almost the same time. Data analysis techniques in this study used two approaches, namely qualitative and quantitative approaches. In the qualitative approach, the data is obtained from data reduction, while the quantitative approach uses descriptive analysis. To determine the level of women's welfare using the CIBEST model welfare measurement tool. The results of the research found that the role of women is able to improve welfare through empowerment programs. The effect of the empowerment program on welfare can be seen in the average difference (mean diference) welfare before participating in the empowerment program and after participating in the empowerment program from an average welfare of 5.14 to an average of 5.69. Through the analysis of the CIBEST approach, the role of women in improving family welfare is illustrated by changes in the index in a better direction, namely changes in the material poverty index decreased by 41.9%, changes in the spiritual poverty index have the same index, namely 0 (zero), changes in the absolute poverty index decreased by 1%, and changes in the welfare index increased by 42.9%. Keywords: Role, Women, Empowerment, CIBEST