bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sobre fracaso constitucional, constitucionalismo transformador y utopismoOn constitutional failure, Transformative Constitutionalism, and Utopianism
Authors: Landau David , Dixon Rosalind 
Published: December 2023

Abstract
In this brief epilogue, we reflect on the articles in this symposium to ask two questions that are particularly important to transformative constitutionalism. First, what is constitutional failure? While this symposium focuses on constitution-making episodes that never result in a final text, projects might be seen as failures even if they formally go into effect, because they fail to produce on the ground change. Transformative constitutional projects often pay more attention to the articulation of rights than the pathways through which these rights are implemented. Such a text can fall prey to structural utopian constitutionalism, where there is no path to implement ambitious programmatic content. Second, we ask: what causes constitutional failure? The essays in this symposium highlight essentially political reasons, particularly the failure to build sufficient political support from parties and other stakeholders. Constitution-making without such support from political insiders, such as the 2022 Chilean draft or the Icelandic draft, risks falling into sociological utopian constitutionalism and may fail to launch. Examining the failures in this symposium, particularly the overwhelming loss of the 2022 Chilean draft, may help avoid situations where transformation slides into utopianism.
Extent of community pharmacists’ care of clients with depression in Enugu, Nigeria: a cross-sectional survey
Authors: Anosike Chibueze , Adibe Maxwell Ogochukwu , Ani Desmond Nnia 
Published: December 2023

Abstract

Background
Community pharmacists play a crucial role in the care of people with depression. This study aimed to evaluate the level of care provided by community pharmacists for clients with depression in Enugu, Nigeria.

Methods
A cross-sectional survey was conducted among randomly selected community pharmacists in Enugu, Nigeria. The data obtained were analysed descriptively.

Key findings
Approximately 25% of pharmacists perform depression screening, and 14.4% refer clients to psychiatrists. Pharmacists rarely provide information on antidepressant dosage, side effects, frequency, and duration.

Conclusion
Community pharmacists in Enugu are not providing effective care to depressed patients. Thus, appropriate interventions are recommended.
The Securitization of Asylum: A Review of UK Asylum Laws Post-Brexit
Authors: Saenz Perez Cristina 
Published: December 2023

Abstract
Understanding the role of external actors is essential to understanding the United Kingdom’s (UK) securitization agenda in the field of asylum. Whilst the internal dynamics of securitization in migration and asylum and its links to the Brexit referendum have been extensively analysed, the externalization of asylum and its connection to the so-called ‘hostile environment’ policy have received less attention. This article addresses this gap, and focuses on how the Nationality and Borders Act 2022 and the UK–Rwanda Memorandum of Understanding for the relocation of asylum seekers advance the externalization of asylum post-Brexit. It examines how these reforms reinforce the securitization that characterizes the UK’s asylum and migration policy and evaluates how they exclude asylum seekers from access to basic human rights, in violation of the 1951 Refugee Convention and the European Convention on Human Rights.
The shape of an axisymmetric meniscus in a static liquid pool: effective implementation of the Euler transformation
Authors: Naghshineh Nastaran , Reinberger W Cade , Barlow Nathaniel S , Samaha Mohamed A , Weinstein Steven J 
Published: December 2023

Abstract
We examine the classical problem of the height of a static liquid interface that forms on the outside of a solid vertical cylinder in an unbounded stagnant pool exposed to air. Gravitational and surface tension forces compete to affect the interface shape as characterized by the Bond number. Here, we provide a convergent power series solution for interface shapes that rise above or fall below the horizontal pool as a function of contact angle and Bond number. We find that the power series solution expressed in terms of the radial distance from the wall is divergent, and thus rewrite the divergent series as a new power series expressed as powers of an Euler transformed variable; this series is modified to match the large distance asymptotic behaviour of the meniscus. The Euler transformation maps non-physical singularities to locations that do not restrict series convergence in the physical domain, while the asymptotic modification increases the rate of convergence of the series overall. We demonstrate that when the divergent series coefficients are used to implement the Euler transformation, finite precision errors are incurred, even for a relatively small number of terms. To avoid such errors, the independent variable in the governing differential equation is changed to that of the Euler transform, and the power series is developed directly without using the divergent series. The resulting power series solution is validated by comparison with a numerical solution of the interface shape and the small Bond number matched asymptotic solution for the height of the interface along the cylinder developed by Lo (1983, J. Fluid Mech., 132, p.65-78). The convergent power series expansion has the ability to exceed the accuracy of the matched asymptotic solution for any Bond number given enough terms, and the recursive nature of the solution makes it straightforward to implement.
Using deep learning to accurately detect sow vulva size in a group pen with a single camera
Authors: Chang Shen-Chang , Wu Xin-Ru , Kuan Hao-Yuan , Peng Shao-Yu , Chang Chia-Ying 
Published: December 2023

AbstractThis paper presents a non-contact method for the detection of changes in sow vulva size in a group pen. The traditional approach to estrus detection is manually pressing down on the back of the sow to elicit standing responses; however, this method causes undue distress for sows not in estrus. When a sow is in estrus, the vulva is red and swollen due to the presence of endocrine. Monitoring changes in vulva size to detect estrus with as little impact on the sow as possible is the focus of this study. This is achieved using a single camera combined with a deep learning framework. Our approach comprises two steps: vulva detection and vulva size conversion. Images of sows of Yorkshire, Landrace, and Duroc breeds were collected in group housing, and the vulva was detected through artificial markers and the network architecture of YOLO v4. Based on the internal and external parameters of the camera, the detected size was converted into millimeters and the results of manual measurement (MM) and automatic calculation combined to calculate the size of the vulva. Analysis of the calculated size compared with MM indicates that the object recognition rate of the system exceeds 97.06%, with a size error of only + 1.70 to −4.47 mm and high-calculation efficiency (&gt;2.8 frames/s). Directions for future research include the automatic detection of pig width.
Much work to do about measuring work
Authors: Bradley Cathy J , Kitchen Sara , Owsley Kelsey M 
Published: December 2023

Abstract
Work ability is a critical economic and well-being indicator in cancer care. Yet, work ability is understudied in clinical trials and observational research and is often undocumented in medical records. Despite agreement on the importance of work from well-being, health insurance, and financial perspectives, standardized approaches for collecting, measuring, and analyzing work outcomes are lacking in the health-care setting. The necessary components for closing the gap in patient and caregiver employment research in health-care settings involve a common set of measures, including those that replace or translate generic measures of mental and physical functioning into work outcomes in observational and clinical trial research, standardized approaches to data collection and documentation, and the use of longitudinal data to understand the consequences of reduced work ability over time. We present a conceptual framework for the inclusion of work ability in outcomes research. We cover constructs for employment and work ability measurement that can be adopted in research, recorded as patient-level data, and used to guide treatment decisions. The inclusion of return to work and hours worked, productivity, and ability to perform in a similar job can support conversations that guide treatment decisions and minimize economic consequences. Our hope is that by considering impact on work ability, improved treatments will be developed, health inequities reduced, and resources directed toward aiding patients and their caregivers in balancing work and health demands.
The effects of third-party intervention in the adjudication of maritime delimitation disputes
Authors: Aw Stephany 
Published: December 2023

ABSTRACT
Although the adjudication of a maritime boundary dispute is usually a bilateral process, it is also often the case that third States have an interest in the delimitation to be carried out. Coupled with the potential for the delimitation decisions of courts and tribunals to impact their maritime claims or entitlements, this raises the concern that third State interests could be prejudiced by such a dispute settlement process, without their participation. While third-party intervention has been suggested as a possible means of recourse for such third States, this article argues that third States may, in practice, be hesitant of resorting to intervention. This is because attempts to intervene, whether successful or unsuccessful, are likely to entail the court or tribunal’s eventual decision having some legally binding effects on the third State. Further, alternative options remain available to third States desirous of a platform to make their interests known.
Science fiction and self-transcendence: evidence from retrospective, experimental, and longitudinal studies
Authors: Wu Fuzhong , Zhang Zheng 
Published: December 2023

Abstract
This study proposes that science fiction (sci-fi), a specific entertainment genre or theme, can facilitate self-transcendence (i.e., moving beyond self-boundaries) by inducing epistemic humility (i.e., awareness of one’s epistemic limits accompanied by epistemic openness). Through increasing self-transcendence, sci-fi engagement can further promote prosocial intentions in a real-world context. We conducted three studies with different paradigms to test our hypotheses. Through a retrospective design, Study 1 found that sci-fi (vs. comedy or romance) films were recalled as eliciting stronger self-transcendence. Studies 2a and 2b, using an experimental design, revealed that sci-fi (vs. realistic) narratives induced stronger epistemic humility, and consequently led to heightened self-transcendence. Study 3, extending the findings in the pandemic context through a three-wave longitudinal design, demonstrated that sci-fi engagement within one month predicted the subsequent increase in self-transcendence, which in turn promoted coronavirus disease (COVID)-related prosocial intention over time. The potential of sci-fi to foster self-transcendence and prosociality is discussed.
A novel tetratricopeptide-repeat protein, TTP1, forms complexes with glutamyl-tRNA reductase and protochlorophyllide oxidoreductase during tetrapyrrole biosynthesis
Authors: Herbst Josephine , Pang Xiaoqing , Roling Lena , Grimm Bernhard 
Published: December 2023

Abstract
The biosynthesis of the tetrapyrrole end-products chlorophyll and heme depends on a multifaceted control mechanism that acts primarily at the post-translational level upon the rate-limiting step of 5-aminolevulinic acid synthesis and upon light-dependent protochlorophyllide oxidoreductase (POR). These regulatory processes require auxiliary factors that modulate the activity, stability, complex formation, and subplastidal localization of the relevant proteins. Together, they ensure optimal metabolic flow during the day and at night. As an Arabidopsis homolog of the POR-interacting tetratricopeptide-repeat protein (Pitt) first reported in Synechocystis, we characterize tetrapyrrole biosynthesis-regulating tetratricopeptide-repeat protein1 (TTP1). TTP1 is a plastid-localized, membrane-bound factor that interacts with POR, the Mg protoporphyrin monomethylester cyclase CHL27, glutamyl-tRNA reductase (GluTR), GluTR-binding protein, and FLUORESCENCE IN BLUE LIGHT. Lack of TTP1 leads to accumulation of GluTR, enhanced 5-aminolevulinic acid synthesis and lower levels of POR. Knockout mutants show enhanced sensitivity to reactive oxygen species and a slower greening of etiolated seedlings. Based on our studies, the interaction of TTP1 with GluTR and POR does not directly inhibit their enzymatic activity and contribute to the control of 5-aminolevulinic acid synthesis. Instead, we propose that TTP1 sequesters a fraction of these proteins on the thylakoid membrane, and contributes to their stability.
‘Are you a refugee like us? Oh then we have hope!’ Affective discursive encounters in doing insider Other research
Authors: Sereke Wegahta B 
Published: December 2023

Abstract
In this article, I reflect on how paying attention to the flow of affect between participants and the researcher during interviews unveils knowledge that highlights inequalities and advances a decolonial approach. I specifically discuss the capacity of productive discomfort in revealing valuable insights about the lived experiences of forced migrants and in uncovering knowledge that might otherwise stay hidden. In doing so, I demonstrate how my positionality as an ‘insider Other’ and my approach to interviews as affective encounters open up profound layers of experiences and sense-making. Expanding upon this, the study presents a unique framework that combines the method of interviews, conceptualized as situated affective encounters, with an affective-discursive analytical framework that views affect as intertwined with meaning and discourse. This fusion emphasizes the significance of emotions as a source of knowledge in the research process. The study highlights how this approach contributes to the reflexivity turn in migration studies and elucidates how the combined framework can guide researchers to work with discomfort. This can be a source of insight, as demonstrated by reflecting on my own research on the lived experiences of Eritrean migrants. I use several excerpts from my data to demonstrate how viewing emotions as meaningful leads to nuanced interpretations, thereby enriching insights into the living conditions of those who arrived as forced migrants.
Modelling the orbital histories of satellites of Milky Way-mass galaxies: testing static host potentials against cosmological simulations
Authors: Santistevan Isaiah B , Wetzel Andrew , Tollerud Erik , Sanderson Robyn E , Moreno Jorge , Patel Ekta 
Published: December 2023

ABSTRACT
Understanding the evolution of satellite galaxies of the Milky Way (MW) and M31 requires modelling their orbital histories across cosmic time. Many works that model satellite orbits incorrectly assume or approximate that the host halo gravitational potential is fixed in time and is spherically symmetric or axisymmetric. We rigorously benchmark the accuracy of such models against the FIRE-2 cosmological baryonic simulations of MW/M31-mass haloes. When a typical surviving satellite fell in ($3.4\!-\!9.7\, \rm {Gyr}$ ago), the host halo mass and radius were typically 26–86 per cent of their values today, respectively. Most of this mass growth of the host occurred at small distances, $r\lesssim 50\, \rm {kpc}$, opposite to dark matter only simulations, which experience almost no growth at small radii. We fit a near-exact axisymmetric gravitational potential to each host at z = 0 and backward integrate the orbits of satellites in this static potential, comparing against the true orbit histories in the simulations. Orbital energy and angular momentum are not well conserved throughout an orbital history, varying by 25 per cent from their current values already $1.6\!-\!4.7\, \rm {Gyr}$ ago. Most orbital properties are minimally biased, ≲10 per cent, when averaged across the satellite population as a whole. However, for a single satellite, the uncertainties are large: recent orbital properties, like the most recent pericentre distance, typically are ≈20 per cent uncertain, while earlier events, like the minimum pericentre or the infall time, are ≈40–80 per cent uncertain. Furthermore, these biases and uncertainties are lower limits, given that we use near-exact host mass profiles at z = 0.
Generating images of the M87* black hole using GANs
Authors: Mohan Arya , Protopapas Pavlos , Kunnumkai Keerthi , Garraffo Cecilia , Blackburn Lindy , Chatterjee Koushik , Doeleman Sheperd S , Emami Razieh , Fromm Christian M , Mizuno Yosuke , Ricarte Angelo 
Published: December 2023

ABSTRACT
In this paper, we introduce a novel data augmentation methodology based on Conditional Progressive Generative Adversarial Networks (CPGAN) to generate diverse black hole (BH) images, accounting for variations in spin and electron temperature prescriptions. These generated images are valuable resources for training deep learning algorithms to accurately estimate black hole parameters from observational data. Our model can generate BH images for any spin value within the range of [−1, 1], given an electron temperature distribution. To validate the effectiveness of our approach, we employ a convolutional neural network to predict the BH spin using both the GRMHD images and the images generated by our proposed model. Our results demonstrate a significant performance improvement when training is conducted with the augmented data set while testing is performed using GRMHD simulated data, as indicated by the high R2 score. Consequently, we propose that GANs can be employed as cost-effective models for black hole image generation and reliably augment training data sets for other parametrization algorithms.
The SAMI-Fornax Dwarfs Survey – IV. Star formation histories of dwarf and early-type galaxies: insights from full spectral fitting
Authors: Romero-Gómez J , Aguerri J A L , Peletier Reynier F , Mieske Steffen , van de Ven Glenn , Falcón-Barroso Jesús 
Published: December 2023

ABSTRACT
We present a study on the star formation histories (SFHs) of galaxies covering the range 104 &lt; M⋆/M⊙ &lt; 1012, leveraging full spectral fitting algorithms. Our sample consists of 31 dwarf galaxies from the SAMI-Fornax Survey with stellar masses between 107–$10^{9.5} \, {\rm M}_{\odot }$, early-type galaxies from the ATLAS3D project with stellar masses between 1010–$10^{12} \, {\rm M}_{\odot }$, and dwarf galaxies that are satellites of Andromeda and the Milky Way, with 104 &lt; M⋆/M⊙ &lt; 108. We find that galaxies from 107–$10^{8} \, {\rm M}_{\odot }$ exhibit the smallest star formation rates (SFRs), while the SFR increase as we move down or up in mass. In this sense, we find that some $10^{5} \, {\rm M}_{\odot }$ galaxies have cumulative SFHs that are comparable to those of $10^{12} \, {\rm M}_{\odot }$ galaxies. Our study shows that the evolution of giant galaxies is primarily governed by their internal properties, with time-scales that do not depend on their environmental location. In contrast, dwarf galaxies below $10^{8} \, {\rm M}_{\odot }$ can be significantly affected in dense environments, such as the inner regions of a cluster, that severely quench the galaxies before the assembly of their 50 per cent present-day mass. We find that, only dwarfs with stellar masses between 107–$10^{9} \, {\rm M}_{\odot }$ actively form stars nowadays, while less massive galaxies seem to remain unaffected by the environment due to the expulsion of most of their gas at an early stage in their evolution. Our study highlights and corroborates a critical threshold around $10^{8}-10^{9} \, {\rm M}_{\odot }$ in galaxy evolution from previous studies, separating more massive galaxies minimally impacted by the environment from those less massive galaxies quenched by it.
Cholesterol homeostasis confers glioma malignancy triggered by hnRNPA2B1-dependent regulation of SREBP2 and LDLR
Authors: Zhang Juan , Liu Bei , Xu Changwei , Ji Chenchen , Yin Anan , Liu Yifeng , Yao Yan , Li Bowen , Chen Tangdong , Shen Liangliang , Wu Yuanming 
Published: December 2023

Abstract

Background
Dysregulation of cholesterol metabolism is a significant characteristic of glioma, yet the underlying mechanisms are largely unknown. N6-methyladenosine (m6A) modification has been implicated in promoting tumor development and progression. The aim of this study was to determine the key m6A regulatory proteins involved in the progression of glioma, which is potentially associated with the reprogramming of cholesterol homeostasis.

Methods
Bioinformatics analysis was performed to determine the association of m6A modification with glioma malignancy from The Cancer Genome Atlas and Genotype-Tissue Expression datasets. Glioma stem cell (GSC) self-renewal was determined by tumor sphere formation and bioluminescence image assay. RNA sequencing and lipidomic analysis were performed for cholesterol homeostasis analysis. RNA immunoprecipitation and luciferase reporter assay were performed to determine hnRNPA2B1-dependent regulation of sterol regulatory element-binding protein 2 (SREBP2) and low-density lipoprotein receptor (LDLR) mRNA. The methylation status of hnRNPA2B1 promoter was determined by bioinformatic analysis and methylation-specific PCR assay.

Results
Among the m6A-regulatory proteins, hnRNPA2B1 was demonstrated the most important independent prognostic risk factor for glioma. hnRNPA2B1 ablation exhibited a significant tumor-suppressive effect on glioma cell proliferation, GSC self-renewal and tumorigenesis. hnRNPA2B1 triggers de novo cholesterol synthesis by inducing HMGCR through the stabilization of SREBP2 mRNA. m6A modification of SREBP2 or LDLR mRNA is required for hnRNPA2B1-mediated mRNA stability. The hypomethylation of cg21815882 site on hnRNPA2B1 promoter confers elevated expression of hnRNPA2B1 in glioma tissues. The combination of targeting hnRNPA2B1 and cholesterol metabolism exhibited remarkable antitumor effects, suggesting valuable clinical implications for glioma treatment.

Conclusions
hnRNPA2B1 facilitates cholesterol uptake and de novo synthesis, thereby contributing to glioma stemness and malignancy.