bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prognostic value of circulating tumor cells combined with neutrophil-lymphocyte ratio in patients with hepatocellular carcinoma
Authors: Chen Jia-Li , Guo Lu , Wu Zhen-Ying , He Kun , Li Han , Yang Chi , Han Yun-Wei 
Published: February 2024

BACKGROUND
Circulating tumor cell (CTC) count and neutrophil-to-lymphocyte ratio (NLR) are both closely associated with the prognosis of hepatocellular carcinoma (HCC).
AIM
To investigate the prognostic value of combining these two indicators in HCC.
METHODS
Clinical data were collected from patients with advanced HCC who received immune therapy combined with targeted therapy at the Department of Oncology, the Affiliated Hospital of Southwest Medical University, Sichuan, China, from 2021 to 2023. The optimal cutoff values for CTC programmed death-ligand 1 (PD-L1) (+) > 1 or CTC PD-L1 (+) ≤ 1 and NLR > 3.89 or NLR ≤ 3.89 were evaluated using X-Tile software. Patients were categorized into three groups based on CTC PD-L1 (+) counts and NLR: CTC-NLR (0), CTC-NLR (1), and CTC-NLR (2). The relationship between CTC-NLR and clinical variables as well as survival rates was assessed.
RESULTS
Patients with high CTC PD-L1 (+) expression or NLR at baseline had shorter median progression-free survival (mPFS) and median overall survival (mOS) than those with low levels of CTC PD-L1 (+) or NLR (P < 0.001). Meanwhile, patients in the CTC-NLR (2) group showed a significant decrease in mPFS and mOS. Cox regression analysis revealed that alpha-fetoprotein (AFP), CTC PD-L1 (+), and CTC-NLR were independent predictors of OS. The time-dependent receiver operating characteristic curve showed that the area under the curve of CTC-NLR at 12 months (0.821) and 18 months (0.821) was superior to that of AFP and CTC PD-L1 (+).
CONCLUSION
HCC patients with high CTC PD-L1 (+) or NLR expression tend to exhibit poor prognosis, and a high baseline CTC-NLR score may indicate low survival. CTC-NLR may serve as an effective prognostic indicator for patients with advanced HCC receiving immunotherapy combined with targeted therapy.
Large isolated fibrous tumors in the upper esophagus: A case report
Authors: Yu Jia-Jia , Pei Huan-Shuang , Meng Yu 
Published: February 2024

BACKGROUND
Solitary fibrous tumors (SFT) are rare spindle cell tumors that are usually benign. A total of 10 cases of SFTs in the upper esophagus have ever been reported. Here, we report the anesthetic management of a patient with a large isolated fibrous tumor of the upper esophagus compressing the tracheal membrane. We also provide a literature review of the current research.
CASE SUMMARY
We report the case of a 49 year old male with “cough aggravation and wheezing after exercise”, who underwent esophagectomy for a large isolated fibrous tumor compressing the tracheal membrane in the upper esophagus. We advise the use of a single-lumen tube with a blocker in patients with difficult airways to reduce the incidence of airway injury and fibrinoscopy at all stages of the perioperative period to guide airway management. This case study is the first report of the anesthetic management of a large, isolated fibrous tumor compressing the tracheal membrane in the upper esophagus.
CONCLUSION
This rare case emphasizes the importance of perioperative management of anesthesia in patients with large isolated fibrous tumors of the upper esophagus that compress the tracheal membrane. The use of blocker reduce the incidence of airway injury and fibrinoscopy at the perioperative period to guide airway management.
ARCHYTAS MARMORATUS (TOWNSEND) AND LESPESIA SPP. (DIPTERA: TACHINIDAE) PARASITOIDS OF SPODOPTERA FRUGIPERDA (J.E. SMITH) (LEPIDOPTERA: NOCTUIDAE) ON ZEA MAYS L. IN SOUTHERN PUERTO RICO
Authors: Cabrera-Asencio Irma , Viteri Diego M. , Linares-Ramírez Angela M. 
Published: February 2024

ARCHYTAS MARMORATUS (TOWNSEND) AND LESPESIA SPP. (DIPTERA: TACHINIDAE) PARASITOIDS OF SPODOPTERA FRUGIPERDA (J.E. SMITH) (LEPIDOPTERA: NOCTUIDAE) ON ZEA MAYS L. IN SOUTHERN PUERTO RICO
Kiai Charismatic Leadership in Developing The Mamba'ul Ma'arif Denanyar Islamic Boarding School
Authors: Sulthon Sulaiman  , Achmad Patoni  , Ngainun Naim  , Ahmad Supriyadi  
Published: January 2024

This research departs from the development of Islamic boarding schools as educational institutions able to maintain their existence in the dynamics of global education. The dynamization and stabilization of Islamic boarding schools as one of the leading education systems in Indonesia is indeed inseparable from the leadership carried out by the caregivers and managers of Islamic boarding schools. This research took the locus at Yayasan Pondok Pesantren Mambaul Maarif Denanyar Jombang East Java to find answers to the following questions; How is the leadership of kiai concerning policy making for the development of Islamic boarding schools in the Mamba'ul Ma'arif Denanyar Jombang Islamic Boarding School; How is the kiai program program in the development of Islamic boarding schools in the Mamba'ul Ma'arif Islamic Boarding School Denanyar Jombang; How is the development of kiai in the development of Islamic boarding schools in the Mamba'ul Ma'arif Islamic Boarding School Denanyar Jombang. This qualitative research uses a phenomenological approach using a single case design. The research location is Pondok Pesantren Mambaul Maarif Denanyar Jombang, East Java. Data collection techniques use observation, interview and documentation techniques. Data analysis includes single-case analysis and cross-case analysis with data reduction analysis techniques, data presentation and conclusions. The results showed that; Policy making is carried out through; charismatic leadership model approach in policy setting; application of a democratic-consultative collective-collegial leadership system in policy formulation; policy making based on deliberation, and; laughter and spiritual based; The development program includes; development of Islamic boarding school academic programs in the form of shawir activities and peer reading; improvement of pesantren facilities; economic development; the Jalin Alumni program, and; sincerity-based Coaching is carried out through mechanisms; periodic coaching; emphasis on discipline; self-reliance briefing; suppression of civilized behavior; supervision and guidance based on guardians and alumni, and; based on laughter
Ambulatório de desenvolvimento infantil: a inserção da terapia ocupacional em um serviço interdisciplinar de intervenção precoce
Authors: Da Silva Thainá Heloisa Chaves , Valença Maria Luiza Luiza Goes , Silva Ana Alice Pedro dos Santos , Barbosa Aleide Karine Vieira Torres , Ribeiro Patrícia Carneiro , Facundes Vera Lúcia Dutra 
Published: February 2024

Resumo
Contextualização: Buscou-se caracterizar o funcionamento do Ambulatório de Desenvolvimento Infantil (ADI), bem como exemplificar as contribuições da Terapia Ocupacional neste serviço de intervenção precoce. Processo de Intervenção: Trata-se de ambulatório de seguimento para os casos com possíveis sinais de atrasos no desenvolvimento infantil ou fatores de riscos observados, em formato interdisciplinar de orientação a cuidadores, com a presença de profissionais da Terapia Ocupacional, Fisioterapia e Fonoaudiologia concomitantemente. Análise crítica da prática: Com essa forma de atendimento, há estímulos a uma maior participação da família no tratamento, e exemplifica como a interdisciplinaridade é benéfica para o entendimento global do sujeito, bem como a participação do terapeuta ocupacional é necessária, visando o brincar e as demais ocupações como objetivo terapêutico. Síntese das considerações: O ADI é uma importante ferramenta para o rastreio de atrasos no desenvolvimento infantil, assim como o olhar terapêutico ocupacional neste espaço traz intervenções focadas no desempenho ocupacional dessas crianças, tais como o brincar e as atividades de vida diária.
Palavras chave: Desenvolvimento Infantil. Práticas Interdisciplinares. Terapia Ocupacional.
HORTALICERAS MAPUCHE, SIGNIFICADOS ATRIBUIDOS A OCUPACIONES ANCESTRALES
Authors: Antil-Arévalo Catalina , Canales-Bascuñán Carmen , Iturra-Villagrán Araceli , Muttel-Becerra Nancy , Samacá Julián , Sánchez-Medina Bárbara , Vasquez-Espinoza Luis Eduardo 
Published: February 2024

Este estudio resalta una de las ocupaciones más significativas y tradicionales dentro del pueblo Mapuche, ser hortalicera en Temuco, Región de La Araucanía. El análisis de la información se realizó a través de metodología cualitativa de tipo explorando como ocupaciones de tipo ancestral cobran sentido y tienen diversos significados dentro de la cosmovisión y territorio mapuche, empleando la teoría fenomenológica y paradigma interpretativo. Para la obtención de información se aplicó una entrevista semiestructurada, cuyos tópicos fueron: formas ocupacionales, significados, propósitos y contextos. Los principales resultados encontrados indican que la ocupación de hortalicera es una práctica cultural del pueblo Mapuche, la cual está ligada a la naturaleza e influyen en ella los contextos culturales, familiares, institucionales, legales, entre otros. A modo de conclusión se evidencia que el significado que las mujeres hortaliceras mapuche le asignan a su ocupación se construye en base a la relación entre los componentes de su diario vivir, es decir, estos significados son influenciados por las formas ocupacionales, los propósitos y contextos, siendo relevante para la Terapia Ocupacional considerar estos aspectos para realizar intervenciones con sentido y pertinencia cultural.
Fatores estressores e as estratégias de enfrentamento entre os estudantes de graduação de Terapia Ocupacional
Authors: Hainoski Andressa Oshiro , Trevisan Erika Renata 
Published: February 2024

Introdução: A sobrecarga acadêmica no ensino superior tem sido veementemente explorada na literatura, associada a cobranças, sobrecarga de trabalhos acadêmicos, mudança de rotina e manejo de responsabilidades. Todos esses fatores são ao mesmo tempo associados ao estresse. Objetivo: Identificar os fatores estressores e as estratégias de enfrentamento entre os estudantes de graduação de Terapia Ocupacional. Método: O levantamento qualitativo se deu por meio de grupos focais norteados por um roteiro semiestruturado com a análise de conteúdo temática. Resultados: Foram elencadas duas categorias, nas quais foram identificados temas emergentes associados em causa e em efeito quanto à fatores estressores (sobrecarga associada ao meio acadêmico, gerenciamento do tempo, má qualidade de sono, má alimentação, falta de dinheiro, distância de casa e saudade de entes queridos, sentimento de culpa e insegurança sobre a qualidade do aprendizado durante à pandemia) e a estratégias de enfrentamento (consumo de álcool/tabaco/maconha, rede de apoio, dormir em excesso, comer exacerbado, uso de medicações, realização de atividade física e lazer). Conclusão: O meio acadêmico tem um grande impacto na saúde mental dos estudantes de graduação de Terapia Ocupacional e se faz necessário a implementação de programas voltados para promoção de saúde entre estudantes de ensino superior.
Palavras-chave: Estresse psicológico. Ensino Superior. Adaptação Psicológica. Saúde Mental. Terapia Ocupacional.
Impedimento del habla y recursos educativos digitales: revisión sistemática desde la docencia en educación especial en la ciudad de Nueva York, USA
Authors: Made Ana 
Published: February 2024

La presente investigación tuvo como objetivo realizar una revisión de la literatura científica generada entre los años 2010 al 2022, sobre la implementación de recursos educativos digitales en estudiantes con impedimento de habla o trastorno del lenguaje. Para lograr dicho objetivo se realizó una búsqueda en las bases de datos Dialnet, DOAJ, Eric, Scielo, Sopes, Elsevier, Jstor, Oxford Research Encyclopedia y el motor de búsqueda Google Académico, a través de descriptores que incluían las variables asociadas al objeto de estudio. En una búsqueda inicial se obtuvieron 53 artículos, que al ser depurados según criterios derivaron en 15 artículos que cumplían con los objetivos. Los resultados mostraron dos tendencias claras en la literatura: artículos referidos al uso de recursos didácticos digitales, y artículos que consideran recursos didácticos no digitales en la discapacidad del habla, y se identificaron sus aplicaciones en el ámbito terapéutico y académico. Se discuten las imprecisiones conceptuales relacionadas con la discapacidad de habla o trastorno del lenguaje, y la escasa producción científica en el área, lo cual se asocia a la efectividad en los procesos de inclusión de los estudiantes con dicha discapacidad a través de recursos educativos digitales.
ANALISIS KEMAMPUAN KONEKSI MATEMATIS SISWA MENGGUNAKAN PENDEKATANPEMBELAJARAN MATEMATIKA REALISTIK (PMR)
Authors: Sari Dewi Purnama , Arini Lilis 
Published: January 2024

ABSTRACT
The aim of this research is to find out how students' mathematical connection abilities use the realistic mathematics learning approach (RME) at SMA PAB 5 Klumpang. This type of research is descriptive qualitative research. The research subjects of class X SMA PAB 5 Klumpang consisted of 25 students. The research object was the students' mathematical abilities using a realistic mathematical approach. Data collection techniques used by researchers were observation, interviews and documentation. Data analysis techniques used the Miles and Huberman approach. The level of mathematical connection ability of class Based on the results of research conducted by researchers, it can be concluded that the research subject is (1) students achieve mathematical connection abilities in the high category and are able to produce all indicators in mathematical connection abilities, namely the ability to connect between mathematical topics/concepts, the ability to connect mathematics with other sciences and the ability Mathematical connections to everyday life. (2) students achieve mathematical connection abilities in the low category and are unable to produce a single indicator of mathematical connection abilities. (3) students achieve mathematical connection abilities in the medium category and are able to produce two indicators of mathematical connection abilities, namely the ability to connect between mathematical topics/concepts and the ability to connect mathematics with other sciences.
Sistem Pendukung Keputusan Pemilihan Kampung KB Menggunakan Metode TOPSIS
Authors: Pahlevi Muhammad Rezha , Testiana Gusmelia , Putra Reza Ade 
Published: January 2024

Kampung KB adalah suatu wilayah setara Desa atau setingkat yang mempunyai karakteristik tertentu yang mana terdapat keterpaduan program keluarga berencana dan pembangunan serta kependudukan yang bertujuan mengentaskan kemiskinan, solusi ledakan populasi penduduk dan juga meningkatkan potensi masyarakat. Penelitian ini dilakukan pada Dinas Pengendalian Penduduk dan Keluarga Berencana Kecamatan Tungkal Jaya, bertujuan untuk memberi rekomendasi pemilihan kampung KB menggunakan Sistem Pendukung Keputusan (SPK) yang mengimplementasikan metode Technique for Order Preference by Similarity (TOPSIS) yang mana akan mempertimbangkan 16 alternatif dengan 10 kriteria dan bobotnya sebagai pertimbangan pemilihan kampung KB. Banyaknya alternatif dan kriteria, serta tingkat kepentingan kriteria yang berbeda-beda mempersulit dalam mencapai keputusan dan memungkinkan terjadinya human error. Dengan menggunakan SPK pemilihan kampung KB dapat menjadi lebih optimal dengan mempertimbangkan nilai-nilai dari bobot dan setiap kriteria yang sesuai dengan kebijakan dari Dinas Pengendalian Penduduk dan Keluarga. Metode yang digunakan adalah Technique for Order Preference by Similiarity To Ideal Solution (TOPSIS) karena konsepnya sederhana dan mudah dipahami, komputasinya efisien dan memiliki kemampuan untuk mengukur kinerja relatif dari alternatif-alternatif keputusan dalam bentuk matematis yang sederhana. Metode pengembangan sistem pada penelitian ini ialah metode waterfall, metode ini digunakan karena memiliki alur hidup perangkat lunak yang terurut dan selaras dengan metode TOPSIS. Hasil dari implementasi metode TOPSIS pada pemilihan kampung KB adalah dengan mengurutkan Desa yang memiliki nilai preferensi tertinggi hingga terendah. Sitem yang telah dibangun menunjukkan Desa Simpang Tungkal dengan nilai preferensi tertinggi yaitu 0,624.
Kata Kunci : SPK, TOPSIS, Kampung KB
Medidas Alternativas a la Privación de la Libertad: avances y tensiones en el proceso de institucionalización
Authors: Vera Paula Cecilia 
Published: February 2024

Este trabajo analiza las principales tensiones que emergen cuando se contrasta el proceso de institucionalización de la Dirección de Medidas Alternativas a la Privación de la Libertad de la Provincia de Mendoza y el devenir cotidiano de sus prácticas desde el año 2015 hasta el año 2018. Esta adecuación del quehacer institucional a instrumentos normativos que modulan el devenir del dispositivo penal juvenil ha tenido, en la historia de Medidas Alternativas en la Provincia de Mendoza, distintos momentos de avances que reflejaron el funcionamiento de un programa penal juvenil adherido a la protección de derechos de adolescentes en proceso penal y, disputas sobre la materialidad de las prácticas. El objetivo es analizar y reflexionar sobre los puntos de fuga existentes entre las prácticas y la institución, indagar sobre esos momentos en los que pareciera que el quehacer se autonomiza de la institución que lo ha originado.
PENGARUH ELECTRONIC WORD OF MOUTH TERHADAP KEPUTUSAN PEMBELIAN PADA E-COMMERCE BUKALAPAK DI KECAMATAN SEKAYU
Authors: Anggraini Rizki , . Rumbiati , Marsih Yeni 
Published: February 2024

ABSTRAK
Internet merupakan sarana untuk melakukan transaksi perdagangan. Tujuan dari penelitian ini adalah untuk melihat bagaimana pengaruh electronic word of mouth terhadap keputusan pembelian pada e-commerce bukalapak di Kecamatan Sekayu. Penelitian ini menggunakan analisis kuantitatif deskriptif dengan regresi linear sederhana, jumlah responden sebanyak 85 orang. Hasil penelitian menunjukkan bahwa e-WOM berpengaruh terhadap keputusan pembelian. Pernyataan dari konsumen dalam bentuk ulasan produk akan sangat mempengaruhi keputusan konsumen yang baru terhadap barang yang akan mereka beli.
Keywords: electronic word of mouth, regresi, keputusan pembelian.
ANALISA PENGAMBILAN KEPUTUSAN UNTUK MENENTUKAN SUBKONTRAKTOR SPESIALIS DENGAN METODE TOPSIS
Authors: . Ladika , Sanggoro Heru Bayuaji 
Published: February 2024

ABSTRACT
The building construction sector is a complex industry, so it is necessary to split the work and divide (deliver) it to subcontractors. In determining these subcontractors, stakeholders are faced with many and various methods in making decisions so that the selection of subcontractors can be determined optimally. This study analyzes and compares the two MADM TOPSIS methods. This research takes a case study of the subcontractor selection process carried out by the main contractor at PT. Cipta Griya Semesta. This study consists of 4 alternative subcontractors with 6 assessment criteria with the criteria of general aspects, financial aspects, technical aspects, managerial aspects, work safety aspects and reputation aspects. Based on the ranking results using these 2 methods, subcontractor D will be selected to help carry out the ongoing project.
Keyword: Topsis, Subcontractor, Construction
High-time-resolution analysis of meridional tides in the upper mesosphere and lower thermosphere at mid-latitudes measured by the Falkland Islands SuperDARN radar
Authors: Chisham Gareth , Kavanagh Andrew J. , Cobbett Neil , Breen Paul , Barnes Tim 
Published: February 2024

Abstract. Solar tides play a major role in the dynamics of the upper mesosphere and lower thermosphere (MLT). Hence, a comprehensive understanding of these tides is important for successful modelling of the MLT region. Most ground-based observations of tidal variations in the MLT have been from meteor radar measurements with a temporal resolution of 1 h. Here, we take a different perspective on these tidal variations using high-resolution 1 min neutral-wind measurements from the Falkland Islands SuperDARN (Super Dual Auroral Radar Network) radar. This analysis shows that these higher-resolution data can be used to identify higher frequency tidal components than are typically observed by meteor radars (up to a heptadiurnal component). It also shows evidence of significant power in these higher frequency components, particularly in the quaddiurnal component, which may be particularly suitable for a global analysis using high-resolution SuperDARN neutral-wind measurements. The high-resolution analysis also shows evidence of fluctuations with a frequency of 1.5 cycles per day, as well as higher-frequency fluctuations, accompanying a quasi-2 d (two day) wave. We discuss the limitations of this high-resolution analysis method and the new opportunities that it may provide. We conclude that higher-resolution SuperDARN neutral-wind measurements need to be better exploited in the future as they provide a complementary way of studying tides and waves in the MLT.
INVESTIGATION OF MICROSTRUCTURE FORMATION OF POWDERED STEEL WITH TRIP EFFECT IN DIRECT METAL DEPOSITION
Authors: Куприянова О.А. , Горленко Д.А. , Шекшеев М.А. , Пивоварова К.Г. , Огнева Е.М. , Полякова М.А. 
Published: February 2024

К стратегически значимым технологиям, обеспечивающим инновационное развитие различных отраслей промышленности, в настоящее время относят аддитивные технологии. Актуальными вопросами при их применении являются обеспечение необходимой микроструктуры синтезированного материала и отсутствие дефектов. В данной работе представлены результаты исследования особенностей формирования микроструктуры образцов, полученных прямым осаждением металлов порошковой стали с ТРИП-эффектом. Установлены характерные особенности микроструктуры образцов порошковой стали с ТРИП-эффектом, полученных методом прямого осаждения металлов и традиционным способом металлургического производства. Проведено сравнение микроструктуры образцов, полученных методом прямого осаждения металлов порошковой стали с ТРИП-эффектом и традиционной технологией металлургического производства.
At the current stage of development, additive technologies are classified as strategically significant technologies that provide innovations in various industries. Relevant issues in the application of such technologies are the provision of the necessary microstructure of the synthesized material and the absence of defects. This paper presents the results of the study of the microstructure features of samples obtained in direct metal deposition of powdered steel with TRIP-effect. Typical peculiarities of microstructure of powdered steel with TRIP-effect in direct metal deposition and obtained by traditional metallurgical production method are stated. The microstructure of products obtained by direct metal deposition of powdered steel with TRIP-effect and traditional metallurgical production technology were compared.