bluuebunny/crossref_metadata_2025_split huggingface dataset:
Materiality of Plaster Vessels: The Problem of Southwest Asian Neolithic White Ware
Authors: Nilhamn Bonnie 
Published: December 2023

Abstract
The study of plaster vessels, white ware, from the Late Neolithic Southwest Asia (7000–5000 cal BC) is an untapped source that can provide us with valuable insights into the earliest development of pyrotechnology and Neolithic society. This plaster material is not well known and has not been involved in many studies. Using a symmetrical approach for the case study of plaster ware at Tell Sabi Abyad in Upper Mesopotamia, this article argues that it is crucial to acknowledge materiality in the study of these vessels. The ware resembles pottery in shape, typology, and basic function but is far from it material-wise and in its chaîne opératoire. The material plaster is also often misunderstood and associated primarily with architecture. Therefore, plaster ware stands at the crossroads between being observed as a copy of ceramics and being recognized as portable architecture. This article calls for an interdisciplinary approach, balancing the exact sciences of archaeometry and the theory of materiality. It will also address problems concerning terminology; it proposes replacing the term white ware with “plaster ware” as the most appropriate title for this ware because it can be better understood by a wider audience outside the discipline.
Interval models for uncertainty analysis and degradation prediction of the mechanical properties of rubber
Authors: Yin Shengwen , Lu Yawen , Bai Yu 
Published: December 2023

Abstract
As rubber is a hyperelastic material, its nonlinear deformation behavior during aging is significantly influenced by various factors, including the material characteristics, demonstrating a significant uncertainty. Most of the existing uncertain prediction methods of rubber nonlinear property degradation are based on the probability density function, which requires a large number of samples to obtain the probability distribution and requires a lot of work. Therefore, the interval model is used in this study to characterize the uncertainty. However, the traditional interval constitutive models ignore the correlation between interval variables, and the prediction results have large errors. In order to minimize prediction errors and improve prediction accuracy, an interval Mooney–Rivlin (M–R) correlation model that considers the correlation between parameters was established. To address the influence of uncertainties, an interval Arrhenius model was constructed. The M–R model requires multiple fittings of stress–strain curves to obtain the model parameters, and the prediction process is relatively complex. Therefore, combing the two proposed models, the relationship equations of rubber tensile stress with aging temperature and aging time were first established by interval Arrhenius, and then the interval M–R model was used to obtain the variation ranges of parameters

C

10

{C}_{10}

and

C

01

{C}_{01}

. By contrasting this with the measured rubber aging information, the effectiveness of the proposed model was confirmed. Compared with the prediction model based on the average value, the maximum error of prediction of this model is reduced by about 60%. Compared with the traditional interval model, the prediction region is significantly reduced, which further improves the prediction accuracy. The above results indicate that this interval aging lifetime prediction model is suitable for characterizing the nonlinear stress–strain behavior of rubber-like elastomers.
The Effect of Transfusion and Hypoxia on Cells in an in vitro Model of the Neurovascular Unit
Authors: Ivkin A. A. , Grigoriev E. V. , Khilazheva E. D. , Morgun A. V. 
Published: December 2023

Up to 57% of patients develop postoperative delirium after surgery for congenital heart defects (CHD). To reduce cerebral damage in pediatric patients during CHD surgery it is important to find out what inflicts the worse damage: would it be a systemic inflammatory response (SIR) triggered by transfusion, or hypoxia developed in non-transfused patients? In vitro evaluation of hypoxia and SIR effects on the neurovascular unit (NVU) cells might contribute to finding the answer.The aim of the study was to compare the effect of varying severity hypoxia and SIR on the functional activity of NUV cells in vitro.Materials and methods. An in vitro NVU model was designed including neurons, astrocytes and endotheliocytes. The effect of hypoxia on NVU was evaluated in the control (C) and 4 study groups (H 1–4), formed based on O₂ content in the medium. The C group NVU were cultivated in standard conditions: N₂ — 75%, O₂ — 20%, CO₂ — 5%; H1: N₂ — 99%, O₂ — 1%; H2: N₂ — 98%, O₂ — 2%; H3: N₂ — 97%, O₂ — 3%; H4: N₂ — 96%, O₂ — 4%. The significance of the differences was 0.0125. The effect of interleukin-6 (IL-6) content on NVU was measured by adding to culture medium pediatric patients’ serum with known minimal or maximal SIRS-response. The assessment was made in the Control — an intact NVU model, and 2 study groups — «Minimum» and «Maximum», i. e. samples with minimum or maximum IL-6 content in culture, respectively. The significance of the differences was 0.017. The cells were incubated at a normothermia regimen for 30 minutes. Then, the functional activity of NVU cells was evaluated by measuring transendothelial resistance (TER) for 24 hours and Lucifer Yellow (LY) permeability test at 60 and 90 minutes after the start of the experiment.Results. After incubation under hypoxic conditions, TER changes occurred in all studied groups. However, they were statistically significant only in the group with 1% oxygen content in the medium. TER decrease in this group was observed after 2, 4 and 24 hours. LY permeability also changed at 60 and 90 minutes, similarly — in NVU cultivated with 1% oxygen in the medium. Minimal TER values were documented at 4 hours after patients’ serum was added to NVU cells culture medium, and TER increased at 24 hours in both study groups. Cellular permeability to LY changed significantly after 1 hour exposure in both groups — with minimum and maximum IL-6 content in the medium. Although at 90 minutes, there was no difference between the 3 groups in LY permeability tests.Conclusion. Intensive SIR demonstrated short-term but more deleterious than hypoxia, effect on cells in the NVU model. Hypoxia disrupted functional activity of NUV cells only at 1% O₂ concentration in the medium.
Acuarelas de orquídeas: Arte y ciencia de Rafael Lucas Rodríguez en la Universidad de Costa Rica. Transcripción de los textos de las acuarelas de orquídeas de Rafael Lucas Rodríguez Caballero, que pertenecen a la Universidad de Costa Rica
Authors: Morales Carlos O. 
Published: December 2023

Introducción: El botánico, artista y humanista Rafael Lucas Rodríguez Caballero preparó más de 1000 acuarelas de orquídeas. En 1986 se publicaron 143 de esas acuarelas, que ahora pertenecen a la Universidad de Costa Rica (UCR).
Objetivo: El objetivo de este escrito fue recuperar y editar la información anotada en el reverso de las acuarelas de orquídeas de Rafael Lucas Rodríguez Caballero.
Métodos: En este escrito se recopilan, ordenan y comentan los textos anotados por Rodríguez en el reverso de 147 acuarelas que custodia la UCR, de las cuales aquí se ilustran 12 en formato pequeño.
Resultados: Más de 20 años (1958-1980) de anotaciones diversas por Rodríguez Caballero se compilan aquí. Seis de las acuarelas de la UCR permanecen inéditas. Además, se identificaron al menos 30 referencias bibliográficas citadas en el reverso de las acuarelas.
Conclusiones: Algunas especies de orquídeas que pintó Rodríguez Caballero son tan escasas en la naturaleza, que casi nadie ha vuelto a verlas. La información en estas ilustraciones tiene relevancia histórica y biológica para la conservación de estas especies de orquídeas.
Los pioneros de la entomología en Costa Rica
Authors: Hilje Quirós Luko 
Published: December 2023

Introducción: El estudio de los insectos suscitó el interés de los naturalistas que exploraron Costa Rica desde el siglo XIX, lo cual obedeció a iniciativas personales, y no a un esfuerzo estatal para promover la investigación sistemática de la entomofauna del país, y así continuó por más de un siglo.
Objetivo: Ofrecer una panorámica del desarrollo de la entomología, desde la época republicana hasta la fundación del Museo de Insectos en la Universidad de Costa Rica (UCR).
Métodos: Para reconstruir este proceso, se recurrió especialmente a los archivos y bases de datos de museos y bibliotecas, tanto nacionales como extranjeras.
Resultados: El primero en estudiar los insectos de Costa Rica fue el naturalista alemán Karl Hoffmann, a partir de 1854, pero murió joven. Fue secundado por el suizo Paul Biolley en 1886, quien a su vez formó a José Fidel Tristán como el primer entomólogo costarricense, al tiempo que los ingleses Osbert Salvin y Frederick D. Godman impulsaban Biologia Centrali-Americana, monumental obra de carácter ístmico. Temprano en el siglo XX llegaron varios estadounidenses, entre quienes destacaron William M. Schaus y los esposos Philip y Amelia Calvert. Posteriormente, al fomentarse el desarrollo agropecuario del país, en el decenio de 1930, se impulsó la enseñanza de la entomología aplicada, para lo cual, en diferentes momentos, fueron contratados el estadounidense Charles Ballou y los alemanes Fernando Nevermann y Alexander Bierig. Finalmente, en 1959 la UCR reclutó desde EE. UU. al costarricense Álvaro Wille, quien en 1962 fundó el Museo de Insectos.
Conclusiones: En un intervalo de 110 años se vivió un proceso lento, desarticulado y hasta azaroso en el desarrollo de la entomología en el país, el cual culminó en 1962 con el inicio de la institucionalización de esta disciplina, hasta convertirse en un componente de la vida cotidiana nacional.
Pengaruh model pembelajaran discovery learning terhadap pemahaman siswa pada mata pelajaran geografi
Authors: Marshanda Umi Fadhila , Sumarmi Sumarmi 
Published: December 2023

One of the issues in teaching is the lack of student understanding. This investigation seeks to ascertain whether the Discovery Learning approach to learning has an effect on the comprehension of social studies students in class XI at SMAN 9 Malang City. Using a posttest-only group design, a quasi-experimental approach was used in this investigation. The experimental class was chosen, and the control class was chosen using a purposive sampling technique. In this study, various methods of data analysis were employed, including reliability tests, normality tests, validity tests, and non- parametric tests. The treatment given to the Discovery Learning learning model appears to have an impact on students' comprehension of the environmental impact analysis content, according to research findings. Drawing conclusions from the research results based on descriptive analysis calculations where the average control class is 70.14 while the experimental class has an average of 79.75. In addition, the results of the non-parametric test are also the reason for making a decision which Asymp. Sig value. (2-tailed) is 0.000 less than 0.05, it can be concluded that the research hypothesis is accepted.
Salah satu masalah dalam pengajaran adalah kurangnya pemahaman siswa. Penelitian ini berusaha untuk memastikan apakah pendekatan pembelajaran Discovery Learning berpengaruh untuk membantu pemahaman siswa kelas XI IPS SMAN 9 Kota Malang. Penelitian ini menggunakan desain penelitian berupa posttest-only group design dengan metode quasi experiment. Kelas eksperimen dipilih, dan kelas kontrol dipilih dengan menggunakan teknik purposive sampling. Dalam penelitian ini digunakan berbagai metode analisis data, antara lain uji validitas, uji reliabilitas, uji normalitas, dan uji nonparametric. Hasil dari pengolahan data, mengatakan bahwa pemahaman siswa terhadap materi analisis mengenai dampak lingkungan dipengaruhi oleh penerapan model pembelajaran Discovery Learning di kelas eksperimen. Pengambilan kesimpulan dari hasil penelitian berdasarkan perhitungan analisis deskriptif dimana rata-rata kelas kontrol 70,14 serta kelas eksperimen memiliki rata-rata 79,75. Selain itu hasil dari uji non-parametrik juga menjadi alasan dari pengambilan keputusan yang mana nilai Asymp. Sig. (2-tailed) bernilai 0,000 lebih kecil dari 0,05, maka dapat disimpulkan hipotesis penelitian diterima.
Using generic drug elexacaftor/tezacaftor/ivacaftor+ ivacaftor in patients with cystic fidosis in routine clinical practice
Authors: Krasovskiy S. A. , Kagazezhev R. U. 
Published: December 2023

Cystic fibrosis (CF) is a multisystem disease of exocrine glands with a progressive course. In recent years, targeted (pathogenetic) treatment aimed at correcting the function of the chloride channel has come to the fore in addition to the symptomatic therapy. The greatest effectiveness was demonstrated with the use of the triple combination of the drug elexacaftor (ELX) / tezacaftor (TEZ) / ivacaftor (IVA) + IVA – Trikafta® (Vertex Pharmaceuticals, USA) that has become the “gold standard” of targeted therapy. Currently, there is virtually no information about the effectiveness and safety of the generic products. The aim of the study was to evaluate the efficacy and safety of the generic drug ELX/TEZ/IVA+IVA (Trilexa®) (Tutor S.A.S.I.F.I.A., Buenos Aires, Argentina) in adult patients with CF in real clinical practice.Methods. The 6-month study included patients (n = 11) aged 18 to 46 years with a diagnosis of CF who were prescribed pathogenetic treatment with ELX/TEZ/IVA+IVA. Their external respiration function (forced vital capacity, forced expiratory volume in 1 second), conductivity of sweat fluid electrolytes (sweat test), anthropometric and other clinical and functional data were analyzed. Results. This study demonstrated pronounced positive effects in relation to indicators of respiratory function, sweat test, and nutritional status. The ELX/TEZ/IVA+IVA treatment was well tolerated, with clinical improvement in the form of a decrease in cough intensity, sputum volume, improvement in daily exercise tolerance, height, and body weight. No serious adverse events were recorded and none of the patients discontinued treatment due to adverse reactions.Conclusion. Obvious clinical and functional positive dynamics and safety over 6 months were demonstrated with ELX/TEZ/IVA+IVA combination.
Tiotropium bromide in the treatment of chronic obstructive pulmonary disease
Authors: Titova O. N. , Kuzubova N. A. , Kozyrev A. G. 
Published: December 2023

The aim of this review was to analyze current information on tiotropium bromide as one of the LAMAs. Tiotropium was chronologically the first LAMA in clinical practice. It is administered using a dry powder inhaler or an aerosol inhaler (Respimat soft mist inhaler). Due to the long bronchodilator effect, tiotropium can be inhaled once a day. The drug has a significant effect on functional respiratory parameters, reduces lung hyperinflation, improves exercise tolerance and quality of life. Tiotropium is superior to short-acting bronchodilators and long-acting β2-agonists (LABAs) and is comparable to other LAMAs, as well as combinations of LABAs and inhaled corticosteroids in the prevention of COPD exacerbations. Tiotropium bromide has a favorable safety profile. Generic tiotropium drug products, including Respium®, are currently available in the Russian Federation. A clinical trial confirmed the non-inferiority and safety of generic tiotropium drug compared to the original branded product.Conclusion. Tiotropium is an effective and safe medication for the maintenance treatment of COPD and for reducing COPD exacerbations. The generic tiotropium drug products widen the range of effective inhaled medications available to physicians.
Challenges of Implementing Enterprise Resource Planning and The Role of Knowledge Management
Authors: Zuma Nompumelelo , Sibindi Ntandoyenkosi 
Published: December 2023

Using the National Youth Development Agency (NYDA) as a case study, this paper considers the challenges of implementing enterprise resource planning (ERP). Data was collected from management and employees using both qualitative and quantitative research techniques. The study established challenges beyond the technical issues, these included: misalignment of the system to the organisation processes, product quality and unavailability of the system’s helpdesk, lack of top management support, and lack of pilot testing, insufficient end-user training, resistance to change management, lack of processes integration, poor technology planning and security and risk matters. Furthermore, the management process that resonates on knowledge transfer, knowledge management, and change management poses a complex challenge in the implementation of ERP. The study recommends the alignment of the user environment, effective change management, and knowledge strategies that are essential to drive ERP. It is also recommended to close the gap between what ERP offers and what end users want and can do.
Mekân ve Enstalasyon Kavramı İlişkisi: Tekstil Malzemesinin Yeri
Authors: KÜRE Serap , ÖZSIRKINTI KASAP Handan 
Published: December 2023

Bu araştırmada; mekân ve enstalasyon sanatı kavramlarının birbiriyle ilişkisi ile birlikte tekstil malzemesinin
kullanımını incelenmektedir. Enstalasyon sanatının amacı mekânı (bireysel ve kamusal alan dışında) sanat
ürünü olarak ele almaktır. Bu kapsamda çalışmanın sınırlılığını oluşturan enstalasyon sanatçılarından,
özellikle malzeme olarak tekstil ürünlerini kullanan sanatçılar konuya dahil edilmiştir. Nitel araştırma
yöntemlerinden gözleme ve yoruma dayalı betimsel analiz kullanılan bu çalışmada; Anish Kapoor, Christo &
Jeanne Claude, Do Ho Suh, Ernesto Neto isimli sanatçılar seçilmiş ve eserleri incelenmiştir. Bu kapsamda;
eser-mekân analizi(mekânsal yüzey kullanımı, malzeme, aydınlatma ve tekstil) ve tekstil malzeme
kullanımı(yüzey, renk, doku ve sanat eseri kavramsal açılımı) başlıkları altında irdelenmiştir. Sonuç olarak
bu çalışmanın; enstalasyon sanatının, tekstil malzemesi ve mekân kavramı bütünlüğü ile ele alınarak farklı
bir bakış açısı geliştirmesi ve mekân kavramına sanatsal bir yaklaşım sunması ile gelecek çalışmalara
kaynak olması amaçlanmıştır.
Bir Halkla İlişkiler Faaliyeti Olarak Resimde Galeri Tasvirleri
Authors: YABAN Nesli Tuğban 
Published: December 2023

Tarihi boyunca sanat, insanlığın geçirdiği değişim ve dönüşümlere bağlı olarak adeta evrim geçirmiş,
sanat eserlerinde ya da sanatsal üretimlerde kimi dönem estetik kaygı ön plana çıkarken kimi zaman bir
kavram sanatçılara ilham kaynağı olmuştur. Bu süreçte sanatın ve sanatçının varlığını sürdürebilmesi için
sanatsal üretimlerin ekonomik döngü içine girmesi şüphesiz kaçınılmaz olmuştur. Bu çalışmanın amacı,
sanatseverlerin, koleksiyonerlerin ya da sanatsal pazarlama faaliyetlerinin yürütüldüğü galerilerin iç mekân
görüntülerin yer aldığı resimlerin halkla ilişkiler anlamında işlevsel yönünü ortaya koymaktır. Çalışmada
araştırma yöntemi olarak betimsel analiz yönteminden faydalanılacaktır. Çalışmanın bulguları, araştırmaya
konu olan resimlerin sanat alanının yanı sıra birer halkla ilişkiler faaliyeti olarak araçsallaştırıldıklarına
işaret etmekte ve doğrudan bir iletişim ve halkla ilişkiler faaliyeti olduklarını ortaya koymaktadır. Araştırma
aynı zamanda dolap resimleme örneklerini içermesi açısından da önem arz etmektedir.
Liderazgo educativo: habilidades de los buenos directores de escuelas públicas en Panamá
Authors: Esbrí Montoliú Miguel Ángel , Durán González Rosa Elena 
Published: December 2023

Objetivo: Conocer las habilidades del director educativo de Panamá, por lo que nos centramos en escuelas con directores de primaria de 1.º a 6.º grados.
Originalidad / aporte: Ofrecer una perspectiva sobre el liderazgo educativo en escuelas de Panamá a partir de las percepciones y experiencia de los directores.
Método: Este proyecto de carácter mixto, retoma principalmente las percepciones y la experiencia de los directivos educativos sobre cómo dirigen las escuelas, las características de los directores, características de las escuelas, trayectoria y actividad directiva y política institucional.
Estrategias / recolección de la información: Cuantitativamente, la selección de la muestra se hizo a partir de la caracterización general de los centros educativos del sistema educativo de la República de Panamá del año lectivo 2020 proporcionada por la Oficina de Estadística del Ministerio de Educación. Se diseñó la “Encuesta de percepción de Liderazgo Educativo de directivos de escuelas primarias de Panamá”; cualitativamente, se realizó observación directa y participante, así mismo, se aplicaron encuestas impresas y orales grabadas, donde los directores expresaron sus opiniones libremente.
Conclusiones: Las principales características que los propios directores deben tener para dirigir proyectos son la autoorganización como gestores, los valores personales y la comunicación; el monitoreo temprano del Ministerio de Educación de los docentes que presenten habilidades de liderazgo y su formación como posibles sucesores en la dirección.
Dynamiques des paysages forestiers au Mozambique : étude de l’écologie du Miombo pour contribuer aux stratégies de restauration des terres dégradées
Authors: MONTFORT Frédérique 
Published: December 2023

La dégradation des terres constitue un enjeu écologique, sociologique et économique majeur à l'échelle mondiale. Le Mozambique, qui dispose encore d’une importante ressource forestière dominée par les forêts de Miombo, est particulièrement touché par ce phénomène, avec près d’un quart de ses terres qui seraient déjà dégradées. Ce pays s’est fixé l’objectif ambitieux de restaurer 1 million d’hectares de terres dégradées d’ici 2030. Cependant, il existe très peu de données quantitatives et spatialisées sur l'état des terres et sur la capacité de résilience du Miombo. L'objectif de cette thèse est d'analyser les dynamiques, les caractéristiques et les déterminants de l’évolution des paysages forestiers afin d’alimenter les stratégies de restauration des terres dégradées au Mozambique. Cette étude s’est particulièrement intéressée à comprendre les facteurs de dégradation des terres à l'échelle nationale, à évaluer la résilience de l’écosystème du Miombo dans les systèmes d’agriculture sur brûlis dans la région centrale du pays (Zambézie), et enfin à proposer une approche pour identifier les zones et stratégies potentielles de restauration des paysages forestiers. Dans un premier temps, les analyses de séries temporelles satellitaires (indices de végétation et variables climatiques) ont permis de documenter l’état des terres à l’échelle nationale et de quantifier les facteurs de dégradation et régénération des terres. Des inventaires floristiques, pédologiques et des enquêtes de terrain ont été menés en périphérie du Parc national de Gilé, afin d’analyser les dynamiques de régénération forestière après défriche-brûlis et l’impact des cycles répétés de culture-jachère. Ces connaissances issues des études par télédétection et d’inventaires de terrain ont été combinées dans une approche innovante permettant d’identifier les zones prioritaires de restauration et les options de gestion (restauration passive ou active), afin d’améliorer des fonctions du paysage (accumulation de carbone, connectivité des habitats) et de renforcer la biodiversité. Cette approche s’appuie sur une analyse multicritère et le développement d’indicateurs spatialisés environnementaux et sur les trajectoires des agrosystèmes. Cette thèse contribue à une meilleure compréhension des processus et des facteurs de dégradation des terres ainsi que de l’écologie du Miombo. Elle propose une approche innovante pour contribuer à l'élaboration de projets ou programmes de restauration des paysages forestiers au Mozambique.