bluuebunny/crossref_metadata_2025_split huggingface dataset:
Film Formation of Two‐Stage Acrylic Latexes: Toward Soft‐Core/Hard‐Shell Systems
Authors: Lopes Brito Elvis , Ballard Nicholas 
Published: November 2023

AbstractControlling the colloidal structure of multiphase latex particles offers a route to significant improvements in the mechanical properties of dried films for use in coatings. However, there is often conflict between the morphology that leads to optimum mechanical properties and the morphology that ensures good film formation at reduced temperatures. In this work, the case of two‐stage latex particles in which the second‐stage polymer has a high glass transition temperature (Tg) is considered. First, a number of different core/shell‐like particles with different polymer compositions and particle structures are synthesized by seeded semi‐batch emulsion polymerization. Using these latexes, the importance of phase mixing, particle morphology, and polymer composition with respect to film formation behavior and mechanical performance is discussed. The results highlight that in multiphase latex systems, the film formation behavior is dictated by the interplay between various colloidal and polymeric features of the samples. It is shown that understanding these features offers a route to systems that can match the film formation properties of a low Tg latex, whilst also approaching the mechanical properties of a high Tg polymer.
Football players in light of economic value theory: Critical review and conceptualisation
Authors: Franceschi Maxence , Brocard Jean‐François , Follert Florian , Gouguet Jean‐Jacques 
Published: November 2023

AbstractFootball players represent the key assets of football clubs, and their value determination is therefore at the heart of clubs' investment and decision‐making processes. Unsurprisingly, the topic of player value has attracted the attention of scholars from various disciplines for decades. Despite this, there is a corpus of academic literature, which, although it works empirically with the relevant data, does not discuss any of the concepts related to the terms ‘value’ and ‘price’ in depth. Conversely, there are studies that do so but do not present a unified and coherent concept of the terminologies used. Consequently, no comprehensive definition of the value of football players seems to emerge from the literature. The central aim of this paper is to fill this gap. Based on a critical review of existing literature, we propose a unified framework embedded in subjective value theory, particularly as formulated by the Austrian school of economics. As a result, this work presents a theoretical basis for defining the use value and market value of football players, the comparison of which can improve clubs' decision‐making. In this context, we also discuss the conceptual validity of Transfermarkt values, a widely used crowd‐sourced valuation tool. Overall, we seek to strengthen the link between economic theory and practical management problems in the football industry. Furthermore, our results are not solely limited to football but are also applicable to athlete valuation in other sports.
Cerebellar Volume and Disease Staging in Parkinson's Disease: An ENIGMA‐PD Study
Authors: Kerestes Rebecca , Laansma Max A. , Owens‐Walton Conor , Perry Andrew , van Heese Eva M. , Al‐Bachari Sarah , Anderson Tim J. , Assogna Francesca , Aventurato Ítalo K. , van Balkom Tim D. , Berendse Henk W. , van den Berg Kevin R.E. , Betts Rebecca , Brioschi Ricardo , Carr Jonathan , Cendes Fernando , Clark Lyles R. , Dalrymple‐Alford John C. , Dirkx Michiel F. , Druzgal Jason , Durrant Helena , Emsley Hedley C.A. , Garraux Gaëtan , Haroon Hamied A. , Helmich Rick C. , van den Heuvel Odile A. , João Rafael B. , Johansson Martin E. , Khachatryan Samson G. , Lochner Christine , McMillan Corey T. , Melzer Tracy R. , Mosley Philip E. , Newman Benjamin , Opriessnig Peter , Parkes Laura M. , Pellicano Clelia , Piras Fabrizio , Pitcher Toni L. , Poston Kathleen L. , Rango Mario , Roos Annerine , Rummel Christian , Schmidt Reinhold , Schwingenschuh Petra , Silva Lucas S. , Smith Viktorija , Squarcina Letizia , Stein Dan J. , Tavadyan Zaruhi , Tsai Chih‐Chien , Vecchio Daniela , Vriend Chris , Wang Jiun‐Jie , Wiest Roland , Yasuda Clarissa L. , Young Christina B. , Jahanshad Neda , Thompson Paul M. , van der Werf Ysbrand D. , Harding Ian H. ,   the ENIGMA‐Parkinson's Study
Published: November 2023

AbstractBackgroundIncreasing evidence points to a pathophysiological role for the cerebellum in Parkinson's disease (PD). However, regional cerebellar changes associated with motor and non‐motor functioning remain to be elucidated.ObjectiveTo quantify cross‐sectional regional cerebellar lobule volumes using three dimensional T1‐weighted anatomical brain magnetic resonance imaging from the global ENIGMA‐PD working group.MethodsCerebellar parcellation was performed using a deep learning‐based approach from 2487 people with PD and 1212 age and sex‐matched controls across 22 sites. Linear mixed effects models compared total and regional cerebellar volume in people with PD at each Hoehn and Yahr (HY) disease stage, to an age‐ and sex‐ matched control group. Associations with motor symptom severity and Montreal Cognitive Assessment scores were investigated.ResultsOverall, people with PD had a regionally smaller posterior lobe (dmax = −0.15). HY stage‐specific analyses revealed a larger anterior lobule V bilaterally (dmax = 0.28) in people with PD in HY stage 1 compared to controls. In contrast, smaller bilateral lobule VII volume in the posterior lobe was observed in HY stages 3, 4, and 5 (dmax = −0.76), which was incrementally lower with higher disease stage. Within PD, cognitively impaired individuals had lower total cerebellar volume compared to cognitively normal individuals (d = −0.17).ConclusionsWe provide evidence of a dissociation between anterior “motor” lobe and posterior “non‐motor” lobe cerebellar regions in PD. Whereas less severe stages of the disease are associated with larger motor lobe regions, more severe stages of the disease are marked by smaller non‐motor regions. © 2023 The Authors. Movement Disorders published by Wiley Periodicals LLC on behalf of International Parkinson and Movement Disorder Society.
Obesity alters the circadian profiles of energy metabolism and glucose regulation in humans
Authors: McHill Andrew W. , Thosar Saurabh S. , Bowles Nicole P. , Butler Matthew P. , Ordaz‐Johnson Omar , Emens Jonathan S. , Purnell Jonathan Q. , Gillingham Melanie , Shea Steven A. 
Published: November 2023

AbstractObjectiveGiven the complex interaction among the circadian system, energy metabolism, and obesity, the authors tested whether having obesity impacts the circadian variation in energy and glucose metabolism in humans.MethodsParticipants with BMI either in the healthy weight or obesity ranges were studied in a 5‐day, in‐laboratory protocol that equally distributed behaviors (i.e., sleep, eating, exercise) across 24 h. Energy metabolism was measured at rest and during a standardized exercise bout and blood was sampled before and after each identical study meal to assess glucose and insulin levels.ResultsIn those with a healthy weight, the circadian nadir of energy expenditure, during both rest and exercise, occurred when participants would normally be asleep. However, in those with obesity, this nadir appears to occur during the habitual wake period. Differences in glucose regulation also depended on the circadian phase, such that individuals with obesity appeared to have relatively greater glucose intolerance during the circadian day and produced less insulin during the circadian night.ConclusionsObesity is associated with altered circadian energy and glucose metabolism. Understanding and addressing these associations could lead to strategies that improve body weight and metabolic health in people with obesity.
Prenatal diagnosis of mucopolysaccharidosis type VII facilitating treatment in neonatal period
Authors: Chandler Natalie Jane , Ramachandran Vijaya , Beesley Clare , Otigbah Chineze , Davison James , Ashraf Tazeen 
Published: November 2023

AbstractDuo exome testing was performed on a fetus conceived via in vitro fertilization with an egg donor. The fetus presented with non‐immune hydrops fetalis (NIHF) at 20 + 0 weeks gestation. Two variants were detected in the GUSB gene. Biallelic pathogenic variants cause mucopolysaccharidosis type VII (MPS‐VII), which can present with NIHF prenatally. At the time of analysis and initial report, one variant was classified as likely pathogenic and the other as of uncertain clinical significance. Biochemical testing of the amniotic fluid supernatant showed elevated glycosaminoglycans and low β‐glucuronidase activity consistent with the diagnosis of MPS‐VII. This evidence allowed the upgrade of the pathogenicity for both variants, confirming the diagnosis of MPS‐VII. The infant was born at 36 + 5 weeks and enzyme replacement therapy (ERT) using vestronidase was initiated at 20 days with planning for hematopoietic stem cell transplant ongoing. The ERT therapy has been well tolerated, with decreasing quantitative urine glycosaminoglycans. Long‐term follow up is required to determine whether treatment has been successful. This case demonstrates the utility of alternative testing methods to clarify the pathogenicity of variants and the clinical utility of obtaining a diagnosis antenatally in facilitating treatment in the neonatal period, and specifically highlights MPS‐VII as a treatable cause of NIHF.
Prognostic accuracy of factors associated with poor outcome in prenatally diagnosed sacrococcygeal teratoma: A systematic review and meta‐analysis
Authors: van Heurn Lieke J. , Coumans Audrey , Haak Monique C. , van der Kaaij Annemarth , van Heurn L. W. Ernest , Pajkrt Eva , Derikx Joep P. M. 
Published: November 2023

AbstractSeveral factors associated with poor outcome in patients with prenatally diagnosed sacrococcygeal teratoma (SCT) have been found. However, the prognostic accuracy of these factors has not been well established. Therefore, we aimed to systematically review the prognostic accuracy of factors associated with poor outcome in these patients. We queried Search Premier, COCHRANE Library, EMCARE, EMBASE, PubMed, ScienceDirect, and Web of Science databases to identify studies regarding patients with prenatally diagnosed SCT. Poor outcome was defined as termination of pregnancy (TOP), intrauterine fetal death (IUFD), or perinatal death. We estimated the odds ratio of factors associated with poor outcome. Eleven studies (447 patients) were included. Overall mortality, including TOP, was 34.9%. Factors associated with poor outcome in fetuses with prenatally diagnosed SCT were cardiomegaly, hypervascular tumor, solid tumor morphology, fetal hydrops, and placentomegaly. A tumor volume to fetal weight ratio (TFR) of >0.12 before a gestational age of 24 weeks is predictive of poor outcome. The prognostic accuracy of factors associated with poor outcome in fetuses prenatally diagnosed with SCT seems promising. Factors associated with cardiac failure such as cardiomegaly, hypervascular tumor, solid tumor morphology, fetal hydrops, placentomegaly, and TFR >0.12 were found to be predictive of poor outcome.
Eye proteome of Drosophila melanogaster
Authors: Kumar Mukesh , Has Canan , Lam‐Kamath Khanh , Ayciriex Sophie , Dewett Deepshe , Bashir Mhamed , Poupault Clara , Schuhmann Kai , Thomas Henrik , Knittelfelder Oskar , Raghuraman Bharath Kumar , Ahrends Robert , Rister Jens , Shevchenko Andrej 
Published: November 2023

AbstractDrosophila melanogaster is a popular model organism to elucidate the molecular mechanisms that underlie the structure and function of the eye as well as the causes of retinopathies, aging, light‐induced damage, or dietary deficiencies. Large‐scale screens have isolated genes whose mutation causes morphological and functional ocular defects, which led to the discovery of key components of the phototransduction cascade. However, the proteome of the Drosophila eye is poorly characterized. Here, we used GeLC‐MS/MS to quantify 3516 proteins, including the absolute (molar) quantities of 43 proteins in the eye of adult male Drosophila reared on standard laboratory food. This work provides a generic and expandable resource for further genetic, pharmacological, and dietary studies.
People with obesity exhibit losses in muscle proteostasis that are partly improved by exercise training
Authors: Srisawat Kanchana , Stead Connor A. , Hesketh Katie , Pogson Mark , Strauss Juliette A. , Cocks Matt , Siekmann Ivo , Phillips Stuart M. , Lisboa Paulo J. , Shepherd Sam , Burniston Jatin G. 
Published: November 2023

AbstractThis pilot experiment examines if a loss in muscle proteostasis occurs in people with obesity and whether endurance exercise positively influences either the abundance profile or turnover rate of proteins in this population. Men with (n = 3) or without (n = 4) obesity were recruited and underwent a 14‐d measurement protocol of daily deuterium oxide (D2O) consumption and serial biopsies of vastus lateralis muscle. Men with obesity then completed 10‐weeks of high‐intensity interval training (HIIT), encompassing 3 sessions per week of cycle ergometer exercise with 1 min intervals at 100% maximum aerobic power interspersed by 1 min recovery periods. The number of intervals per session progressed from 4 to 8, and during weeks 8–10 the 14‐d measurement protocol was repeated. Proteomic analysis detected 352 differences (p < 0.05, false discovery rate < 5%) in protein abundance and 19 (p < 0.05) differences in protein turnover, including components of the ubiquitin‐proteasome system. HIIT altered the abundance of 53 proteins and increased the turnover rate of 22 proteins (p < 0.05) and tended to benefit proteostasis by increasing muscle protein turnover rates. Obesity and insulin resistance are associated with compromised muscle proteostasis, which may be partially restored by endurance exercise.
Design of an effective small expression tag to enhance GPCR production in E. coli‐based cell‐free and whole cell expression systems
Authors: Cho Seongyeon , Lee Haein , Han Yong Hee , Park Tae Shin , Seo Sang Woo , Park Tai Hyun 
Published: November 2023

AbstractG protein‐coupled receptors (GPCRs) play crucial roles in sensory, immune, and tumor metastasis processes, making them valuable targets for pharmacological and sensing applications in various industries. However, most GPCRs have low production yields in Escherichia coli (E. coli) expression systems. To overcome this limitation, we introduced AT10 tag, an effective fusion tag that could significantly enhance expression levels of various GPCRs in E. coli and its derived cell‐free protein synthesis (CFPS) system. This AT10 tag consisted of an A/T‐rich gene sequence designed via optimization of translation initiation rate. It is translated into a short peptide sequence of 10 amino acids at the N‐terminus of GPCRs. Additionally, effector proteins could be utilized to suppress cytotoxicity caused by membrane protein expression, further boosting GPCR production in E. coli. Enhanced expression of various GPCRs using this AT10 tag is a promising approach for large‐scale production of functional GPCRs in E. coli‐based CFPS and whole cell systems, enabling their potential utilization across a wide range of industrial applications.
Fungal seed treatments of cotton affect boll weevil development
Authors: Cunha Janaina C. S. , Rivera Vega Loren J. , Torres Jorge B. , Suh Charles P.C. , Sword Gregory A. 
Published: November 2023

AbstractBACKGROUNDNonpathogenic fungi associated with plants can enhance plant defenses against stress factors, including herbivory. This study assessed whether cotton plants grown from seeds treated with different fungi affected boll weevil,Anthonomus grandis grandisBoheman, development and reproduction along with plant tolerance. We used whole plants grown from seeds treated with different fungi (Chaetomium globosumTAMU520 and TAMU559,Phialemonium inflatumTAMU490, andBeauveria bassiana)versusnon‐treated controls to test insect growth, reproduction, and plant tolerance assays in a greenhouse.RESULTSRegarding boll weevil reproduction, fewer larvae hatched and fewer adults emerged from fungal‐treated plants. In addition, the developmental time from oviposition to adult emergence was delayed in the plants treated with all fungi. For plant tolerance,B. bassiana‐treated plants attacked by boll weevils shed fewer squares than nonfungal‐treated plants.CONCLUSIONFungal treatments can affect boll weevil performance and reproduction on cotton plants, with potentially negative effects on population growth. Collectively, these results support the potential for cottonseed treatments with fungi as a novel tool for boll weevil management in the field. © 2023 The Authors.Pest Management Sciencepublished by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
The influence of the Chinese hukou system in motivating and shaping the geography of Chinese international student mobility
Authors: Kang Erli 
Published: November 2023

AbstractThe hukou system (household registration system) is a long‐established and significant institutional barrier to population movement within China and, accordingly, has been the subject of a great deal of research. What has received scant attention, however, is the influence that this system has on the considerable phenomenon of Chinese international student mobility (ISM). This paper is based on an analysis of 50 semistructured interviews with Shanghai‐based returnee students. Utilising the notions of institutional barriers to migration and middle‐category migration, it illustrates the important role that the hukou system plays in motivating nonelite Chinese students to study abroad and how this institutional barrier shapes their strategic decision making across various temporal phases of the ISM process. These findings are of significance as they highlight the largely unacknowledged role of hukou in the Chinese ISM system. Conceptually, they emphasise the importance of sufficiently accounting for institutional barriers to internal and international mobility in the experiences of international students in migration studies.
Polysaccharides (pectin, mucilage, and fructan inulin) and their fermented products: A critical analysis of their biochemical, gut interactions, and biological functions as antidiabetic agents
Authors: El‐Nashar Heba A. S. , Taleb Mohamed , EL‐Shazly Mohamed , Zhao Chao , Farag Mohamed A. 
Published: November 2023

AbstractDiabetes mellitus is a globally metabolic endocrine syndrome marked by a deficiency of insulin secretion (type‐1 DM) or glucose intolerance arising from insulin response impairment (type‐2 DM) leading to abnormal glucose metabolism. With an increasing interest in natural dietary components for diabetes management, the identification of novel agents witnessed major discoveries. Plant‐derived mucilage, pectin, and inulin are important non‐starch polysaccharides that exhibit effective antidiabetic properties often termed soluble dietary fiber (SDF). SDF affects sugar metabolism through multiple mechanisms affecting glucose absorption and diffusion, modulation of carbohydrate metabolizing enzymes (α‐amylase and α‐glucosidase), ameliorating β‐pancreatic cell dysfunction, and improving insulin release or sensitivity. Certain SDFs inhibit dipeptidyl peptidase‐4 and influence the expression levels of genes related to glucose metabolism. This review is designed to discuss holistically and critically the antidiabetic effects of major SDF and their underlying mechanisms of action. This review should aid drug discovery approaches in developing novel natural antidiabetic drugs from SDF.
A pathway to personal, population and planetary health for dietitians and nutrition professionals
Authors: MacKenzie‐Shalders Kristen L. , Barbour Liza , Charlton Karen , Cox Gregory R. , Lawrence Mark , Murray Sandra , Newberry Kylie , Senior Nicole M. , Stanton Rosemary , Tagtow Angela M. 
Published: November 2023

AbstractBackgroundEarth and all its inhabitants are threatened by a planetary crisis; including climate change, deforestation, biodiversity loss and pollution. Dietitians and nutrition professionals have a responsibility to lead transformational change in contemporary food and health systems to help mitigate this crisis. The study aims to develop a conceptual framework to support dietitians towards personal, population and planetary health.MethodsNon‐empirical methods were used by the co‐researchers to explore and explain the application of an international framework ‘Next‐Generation Solutions to Address Adaptive Challenges in Dietetics Practice: The I + PSE Conceptual Framework for Action’.ResultsA non‐sequential pathway guide to personal, population and planetary health for nutrition professionals was developed including several key guiding principles of Agency, Action, Ascension, Alignment, Alliance and Allyship, and Advocacy and Activism. Each guiding principle features descriptors and descriptions to enhance dietitian and nutrition professional Agency (i.e. vision, self‐belief, confidence, strength and responsibility), Action (i.e. start, shift, translate, achieve and commit), Ascension (i.e. build, overcome, manage, challenge and progress), Alignment (i.e. leadership, transparency, diplomacy, values and systems), Alliance and Allyship (i.e. support, collaborate, represent, community and citizenship) and Advocacy and Activism (i.e. disrupt, co‐design, transform, empower and urgency). The framework and its descriptors support enhanced understanding and are modifiable and flexible in their application to guide the participation of dietitians and nutrition professionals in transformational change in personal, population and planetary health. This guide acknowledges that First Nations knowledge and customs are important to current and future work within this field.ConclusionsAlongside the international body of work progressing in this field, this framework and visual guide will support dietitians and nutrition professionals to achieve urgent, transformational change in personal, population and planetary health.
Temperature effects, energy shifts, and band entropies of Si semiconductors
Authors: Wang Yu , Yao Chuang , Huang Zhongkai , Bo Maolin 
Published: November 2023

AbstractUnderstanding the electronic properties of silicon semiconductors is important for the preparation of high‐performance semiconductor materials. We calculated the band entropies, electronic structures, and bonding properties of a silicon semiconductor using density functional theory and the binding‐energy and bond‐charge model. The relationship between Si energy and temperature was studied using the tight binding (TB) approximation and bond‐order‐length‐strength (BOLS) theory (BOLS‐TB), with the Si (111) surface as an example. The specific binding energies and bonding properties of Si atoms in different surface atomic layers are discussed by analyzing the X‐ray photoelectron spectra of the Si (111) surface at 953 and 1493 K. This study improves our understanding of how surface properties reflect local bonding states and deepens our understanding of how atomic‐relaxation‐derived Hamiltonian perturbations and temperature influence the binding energy of the surface region. It also contributes to the development of Si‐based semiconductor materials by providing new ideas and methods.
Stabilization of switched positive linear delay system with all subsystems unstable
Authors: Zhang Na , Sun Yuangong 
Published: November 2023

AbstractThis article considers the asymptotic stability of switched positive linear time‐delay system with all subsystems unstable. By constructing new discretized co‐positive Lyapunov‐Krasovskii functions, stability conditions are derived for both the discrete time‐varying delay and distributed time‐varying delay cases. Then the results are also extended to nonpositive switched delay systems. Finally we apply our results to consensus problems of switched multi‐agent systems with time delay. We propose numerical examples to illustrate our approach.