bluuebunny/crossref_metadata_2025_split huggingface dataset:
TOWARD A NEW VIEWPOINT FOR THE ARTIST
Authors: LUKE JOY TURNER 
Published: November 2023

ABSTRACTCommunication between the artist and the scientific and technological community has been so tenuous during the past 50 years that the artist is not using knowledge and techniques which originate in that world. Conversely, the scientists and technicians have little insight into the problems of artists, making it difficult for the artist to obtain information he knows he needs. Some of the concepts and techniques valuable to artists are outlined in this paper with a special emphasis on those relating to color.Artists' pigments and vehicles are rapidly changing. Channels of information are needed to keep him current and knowledgable. The artist must use both additive and subtractive color simultaneously, since the visual world he utilizes in creating a picture consists largely of additive situations, but the mixture of his paints is a subtractive process. Metamerism is a problem for the artist as it is in color matching for industry. Color systems, although long known, have never been adequately utilized. The Munsell system is the most practical one at the present time for several reasons. Expanding the Munsell notation to include a relative intensity dimension for pigments would add to its usefulness. A color slide rule and a table of approximate chroma loss between pairs of additive colors are proposed to aid the artist in creating depth effects, illumination effects and transparency effects. The artist should be practical in obtaining and using the facts of paint technology, but flexible in the application of systematic color in order to keep his options open. The use of color systems and techniques, while of value to every artist, can be used at many levels for differing purposes. Such concepts must be tailored to the individual artist's needs.
Legacy in paediatrics: A concept analysis
Authors: Keller Briana P. , Akard Terrah F. , Boles Jessika C. 
Published: November 2023

AbstractAimTo provide an analysis of legacy and legacy‐oriented interventions in paediatric healthcare.DesignWalker and Avant's method of concept analysis.MethodsUsing Walker and Avant's method, three defining attributes of the concept were determined, followed by antecedents, consequences, and empirical referents of legacy.ResultsIn paediatrics, legacy is co‐authored in relationships, has the capability to outlive the person or event it represents, and elicits the essence of a person or experience. Receiving legacy‐oriented interventions are not a prerequisite for having a legacy, nor is death.ConclusionEngaging in purposeful, individualized legacy‐oriented interventions can improve coping in paediatric patients, families, and providers. By understanding the concept of legacy, providers are better equipped to provide care honouring the unique personhood, relationships, and strengths of children and families in even the most dire circumstances.Implications for the Profession and/or Patient CareUnderstanding the scope and purpose of legacy in paediatrics assists providers in improving patient‐ and family‐centred outcomes by designing interventions that facilitate long‐term coping in patients facing a loss of or significant change in health, normalcy, or life.ImpactLegacy‐oriented interventions are provided at most children's hospitals in the United States, yet no widespread consensus on foundation or scope has been determined. This concept analysis provides evidence‐based guidelines for policy and practice in creating legacy for and with children, providing opportunities to improve quality of care for young patients and their families around the world.Reporting MethodN/A.Patient or Public ContributionNo patient or public contribution.
Workplace ostracism in healthcare: Association with job satisfaction, stress, and perceived health
Authors: Manninen Sirpa M. , Koponen Samuli , Sinervo Timo , Laulainen Sanna 
Published: November 2023

AbstractAimsTo examine (1) the association between healthcare workers' workplace ostracism and job satisfaction, stress and perceived health, and (2) whether this relationship is mediated by loneliness and self‐esteem.DesignA cross‐sectional study.MethodsHealthcare (N = 569) managers and employees (nurses, practical nurses, doctors and social workers) in Finland responded to a semi‐structured survey in January 2021 and evaluated their experiences of workplace ostracism, job satisfaction, stress, perceived health, loneliness and self‐esteem during the last year. To examine the association of these variables, linear regression and mediator model tests were performed.ResultsWorkplace ostracism had a clear direct association with job satisfaction, stress and perceived health. Loneliness fully mediated the relationship between workplace ostracism, stress and perceived health, and partly mediated the association between workplace ostracism and job satisfaction. Self‐esteem partly mediated the association between workplace ostracism, stress, job satisfaction and perceived health.ConclusionThe experience of workplace ostracism in organizations is a significant factor in job satisfaction, stress and perceived health. Healthcare organizations could strengthen job satisfaction and increase workers' well‐being by strengthening social relationships in the organization and, via that, reducing turnover intention.Implications for the profession and patient careThis study gives understanding and information to the healthcare profession on how workplace ostracism affects work well‐being and workplace relationships. Workplace ostracism decreases interaction, which can also endanger patient care if information is not openly exchanged.ImpactThis study indicated that workplace ostracism weakened job satisfaction more than loneliness. More commonality and consideration for others at work are needed because these factors may help increase work well‐being and decrease exits from working life. Further research is needed on why workplace ostracism occurs in healthcare workplaces.Reporting MethodSTROBE.Patient or Public ContributionNo patient or public contribution.
Mortality trends, disparities, and social vulnerability in cardiac arrest mortality in the young: A cross‐sectional analysis
Authors: Ibrahim Ramzi , Shahid Mahek , Srivathsan Komandoor , Sorajja Dan , Deshmukh Abhishek , Lee Justin Z. 
Published: November 2023

AbstractBackgroundCardiac arrest (CA) is a leading cause of death in the United States (US). Social determinants of health may impact CA outcomes. We aimed to assess mortality trends, disparities, and the influence of the social vulnerability index (SVI) on CA outcomes in the young.MethodsWe conducted a cross‐sectional analysis of age‐adjusted mortality rates (AAMRs) related to CA in the United States from the Years 1999 to 2020 in individuals aged 35 years and younger. Data were obtained from death certificates and analyzed using log‐linear regression models. We examined disparities in mortality rates based on demographic variables. We also explored the impact of the SVI on CA mortality.ResultsA total of 4792 CA deaths in the young were identified. Overall AAMR decreased from 0.20 in 1999 to 0.14 in 2020 with an average annual percentage change of −1.3% (p = .001). Black (AAMR: 0.30) and male populations (AAMR: 0.14) had higher AAMR compared with White (AAMR: 0.11) and female (AAMR: 0.11) populations, respectively. Nonmetropolitan (AAMR: 0.29) and Southern (AAMR: 0.26) regions were also impacted by higher AAMR compared with metropolitan (AAMR: 0.11) and other US census regions, respectively. A higher SVI was associated with greater mortality risks related to CA (risk ratio: 1.82 [95% CI, 1.77–1.87]).ConclusionsOur analysis of CA in the young revealed disparities based on demographics, with a decline in AAMR from 1999 to 2020. There is a correlation between a higher SVI and increased CA mortality risk, highlighting the importance of targeted interventions to address these disparities effectively.
Evaluation of the accuracy of direct intraoral scanner impressions for digital post and core in various post lengths: An in‐vitro study
Authors: Almalki A. , Conejo J. , Kutkut N. , Blatz M. , Hai Q. , Anadioti E. 
Published: November 2023

AbstractStatement of ProblemDespite the growing utilization of direct intraoral scanners (IOSs) in dentistry, there is a scarcity of research investigating their accuracy, specifically in post and core. Few studies have conducted comprehensive three‐dimensional assessments and comparisons of IOSs with the conventional impression technique, particularly in different post space lengths.PurposeThe purpose of this in vitro study was to digitally assess the accuracy of direct intraoral scanner (IOS) impressions for different post space lengths, specifically 6, 8, and 10 mm.Materials and MethodsA total of 45 typodont teeth (maxillary central incisors) were selected for this study. The teeth underwent endodontic treatment and were divided into three subgroups, each with 15 teeth, based on the desired post space lengths: 6, 8, and 10 mm. Intraoral scans of all specimens were acquired directly using the CEREC Primescan intraoral scanners by two trained examiners. The obtained scan data were compared with conventional impressions obtained using light and heavy bodies of polyvinyl siloxane (PVS). As a control, the conventional impressions were subsequently scanned using an inEos X5a lab scanner. The accuracy of the digital scans was evaluated in the coronal, middle, and apical thirds using the Geomagic Control X software. Statistical analysis was performed using Bonferroni Post‐hoc and One‐way ANOVA tests to analyze the data.ResultsThe overall mean root mean square (RMS) deviations for the different post lengths across the three thirds groups were 58, 81, and 101 μm for the 6, 8, and 10 mm subgroups, respectively. There were no statistically significant differences in the accuracy of the coronal and middle thirds among all subgroups (p > 0.5). However, in the apical third, the 10 mm subgroup exhibited a significantly lower accuracy (163 μm) compared to the 6 mm (96 μm) and 8 mm (131 μm) subgroups (p < 0.05). These results suggest that while the accuracy of intraoral scans using direct IOS impressions was consistent in the coronal and middle thirds regardless of the post length, there was a noticeable decrease in accuracy in the apical third, particularly with longer post lengths.ConclusionConsidering the limitations of this in vitro study, chairside direct IOS impressions offer a viable and clinically acceptable alternative to the conventional impression technique for post space lengths of 6 and 8 mm. However, as the post space length preparation increases, the accuracy of IOS decreases.Clinical SignificanceThe Chairside direct IOS enables expedited and efficient digital impression capture within the root canal, ensuring acceptable accuracy for intracanal post length preparation of up to 8 mm.
Childhood caries is associated with poor health and a faster pace of aging by midlife
Authors: Ruiz Begoña , Broadbent Jonathan M. , Thomson W. Murray , Ramrakha Sandhya , Moffitt Terrie E. , Caspi Avshalom , Poulton Richie 
Published: November 2023

AbstractObjectivesChildhood caries is associated with poorer self‐rated general health in adulthood, but it remains unclear whether that holds for physical health and aging. The aim of this study was to identify whether age‐5 caries is associated with (a) biomarkers for poor physical health, and (b) the pace of aging (PoA) by age 45 years.MethodsParticipants are members of the Dunedin Multidisciplinary Health and Development Study birth cohort. At age 45, 94.1% (n = 938) of those still alive took part. Data on age‐5 caries experience and age‐45 health biomarkers were collected. The PoA captures age‐related decline across the cardiovascular, metabolic, renal, immune, dental and pulmonary systems from age 26 to 45 years. We used (a) generalized estimating equations to examine associations between age‐5 caries and poor physical health by age 45 years, and (b) ordinary least squares regression to examine whether age‐5 caries was associated with the PoA. Analyses adjusted for sex, perinatal health, childhood SES and childhood IQ.ResultsHigh caries experience at age‐5 was associated with higher risk for some metabolic abnormalities, including BMI ≥30, high waist circumference, and high serum leptin. Those with high caries experience at age‐5 were aging at a faster rate by age 45 years than those who had been caries‐free.ConclusionsOral health is essential for wellbeing. Poor oral health can be an early signal of a trajectory towards poor health in adulthood. Management for both conditions should be better‐integrated; and integrated population‐level prevention strategies should be foundational to any health system.
A 24% prevalence of excessive fragmentary myoclonus in 500 consecutive sleep laboratory patients
Authors: Bergmann Melanie , Stefani Ambra , Ibrahim Abubaker , Anselmi Victoria , Brandauer Elisabeth , Högl Birgit , Cesari Matteo 
Published: November 2023

SummaryExcessive fragmentary myoclonus (EFM) is a frequent finding during routine video‐polysomnography (VPSG). We aimed to automatically measure the prevalence of EFM according to current American Academy of Sleep Medicine (AASM) criteria, and the fragmentary myoclonus index (FMI) in sleep stage N1, N2, N3, rapid eye movement (REM) sleep and wake in a large patient population. A total of 500 VPSG recordings of patients admitted to the Sleep Laboratory, Department of Neurology, Medical University of Innsbruck, Austria, between May 1, 2022 and February 28, 2023, were included. EFM according to AASM criteria and FMI were computed by applying a previously validated algorithm. EFM was automatically detected in 121 of the 500 Sleep Laboratory patients (24.2%, 95% confidence interval 20.1%–28.9%). FMI increased with age, male gender, apnea–hypopnea‐index (AHI), oxygen desaturation index (ODI), and periodic leg movements of sleep (PLMS) index. FMI was highest in REM sleep behaviour disorder (RBD), followed by neurodegenerative and internal medicine diseases, but the increase in the FMI was not explained by the disease itself but rather by the age and sex of the patients. Almost a quarter of our patient population had EFM. However, the prevalence of EFM does not allow the drawing of any conclusions about the pathophysiology of EFM or even the determination of a pathological FMI cut‐off value. Associations of the FMI with age, sex, AHI, ODI and PLMS are in line with previous studies, but the FMI needs to be evaluated in different disease entities to learn more about its pathophysiology.
Concurrent hepatopathy in dogs with gallbladder mucocele: Prevalence, predictors, and impact on long‐term outcome
Authors: Jablonski Sara A. , Chen Yue Xiang (Polly) , Williams Jarod E. , Kendziorski Jessica A. , Smedley Rebecca C. 
Published: November 2023

AbstractBackgroundInformation is limited regarding the prevalence and importance of hepatic histologic abnormalities in dogs with gallbladder mucocele (GBM).ObjectivesTo (a) report prevalence of hepatic histologic abnormalities in dogs with GBM (b) evaluate for association between hepatic abnormalities and outcome in dogs with GBM (c) evaluate whether neutrophil‐to‐lymphocyte ratio (NLR) differs in dogs with GBM with and without specific hepatic lesions.AnimalsFifty‐two dogs with grossly and histologically confirmed GBM.MethodsMulticenter, retrospective study of dogs with GBM undergoing cholecystectomy with concurrent liver biopsy. Archived histological sections of gallbladder and liver evaluated by investigators blinded to data. Proportions of dogs with each histologic abnormality alive vs deceased at 1, 3, and 12 months post‐cholecystectomy compared. Mann‐Whitney U performed to determine if NLR differed in dogs with or without selected lesions.Results51/52 (98%, 95% CI [89%, 99%]) dogs with GBM had at least 1 hepatic histologic abnormality. Hepatic fibrosis (37/51; 73%, 95% CI [59%, 83%]), biliary hyperplasia (29/52; 56%, 95% CI [42%, 68%]), and portal inflammation (25/52; 48%, 95% CI [35%, 61%]) were most common. The proportion of dogs alive vs dead differed based on the fibrosis score at 1, 3, and 12 (P ≤ .04) months post‐cholecystectomy. Dogs with hepatic necrosis (P = .006) and cholangitis/cholangiohepatitis (P = .02) had higher NLRs compared to dogs without these lesions.Conclusions and Clinical ImportanceHistologic abnormalities of the liver are common in dogs with GBM. A higher portal fibrosis score might be associated with shortened long‐term survival after cholecystectomy for dogs with GBM. An increase in NLR might predict hepatic necrosis and cholangitis/cholangiohepatitis in dogs with GBM.
Discordance between ABC blood phenotype and genotype in a domestic short‐haired cat
Authors: Ginoudis Argyrios , Canard Bertrand , Kehl Alexandra , Giger Urs , Koutinas Christos , Christoforaki Stella , Smyroglou Erasmia , Polizopoulou Zoe , Mylonakis Mathios E. 
Published: November 2023

AbstractAn adult domestic short‐haired feline leukemia virus‐infected cat was referred for kidney failure and worsening anemia requiring transfusions. ABC blood typing was performed with an immunochromatographic strip assay at different occasions. Gel column systems were used for the major and minor crossmatching tests, and anti‐A and anti‐B titers were determined. No discrete A or B bands appeared on the immunochromatographic strips at any time point for the recipient cat. The recipient's plasma agglutinated RBCs from tested type A and B cats. The recipient's RBCs appeared compatible with plasma from 1 type A and 2 B donors, and incompatible with plasma from another type A cat. Genotyping of recipient blood revealed a single homozygous c.179G>T CMAH variant predicting a blood type B. These studies suggest an unusual weak type B or missing all ABC antigens. The latter resembles the exceedingly rare Bombay phenotype in the human ABO blood group system.
ACVIM Consensus Statement on the management of status epilepticus and cluster seizures in dogs and cats
Authors: Charalambous Marios , Muñana Karen , Patterson Edward E. , Platt Simon R. , Volk Holger A. 
Published: November 2023

AbstractBackgroundSeizure emergencies (ie, status epilepticus [SE] and cluster seizures [CS]), are common challenging disorders with complex pathophysiology, rapidly progressive drug‐resistant and self‐sustaining character, and high morbidity and mortality. Current treatment approaches are characterized by considerable variations, but official guidelines are lacking.ObjectivesTo establish evidence‐based guidelines and an agreement among board‐certified specialists for the appropriate management of SE and CS in dogs and cats.AnimalsNone.Materials and MethodsA panel of 5 specialists was formed to assess and summarize evidence in the peer‐reviewed literature with the aim to establish consensus clinical recommendations. Evidence from veterinary pharmacokinetic studies, basic research, and human medicine also was used to support the panel's recommendations, especially for the interventions where veterinary clinical evidence was lacking.ResultsThe majority of the evidence was on the first‐line management (ie, benzodiazepines and their various administration routes) in both species. Overall, there was less evidence available on the management of emergency seizure disorders in cats in contrast to dogs. Most recommendations made by the panel were supported by a combination of a moderate level of veterinary clinical evidence and pharmacokinetic data as well as studies in humans and basic research studies.Conclusions and Clinical RelevanceSuccessful management of seizure emergencies should include an early, rapid, and stage‐based treatment approach consisting of interventions with moderate to preferably high ACVIM recommendations; management of complications and underlying causes related to seizure emergencies should accompany antiseizure medications.
The dyadic coping experience of ICU transfer patients and their spouses: A qualitative study
Authors: Gu Jiayi , Wang He , Pei Jiaqin , Meng Jingyu , Song Yan 
Published: November 2023

AbstractBackgroundThe patient's spouse, in their role as the primary caregiver, assumes responsibility for the patient's care during the recovery process and provides the most robust social support. Previous research has primarily focused on the coping experiences and thoughts of individual intensive care unit (ICU) patients or caregivers, with limited attention afforded to the relationship between patients and their spouses.AimsThis study aims to explore the dyadic coping experiences of ICU transfer patients and their spouses, with the goal of providing evidence to support the subsequent development of an individualized intervention program.Study DesignA qualitative study using a phenomenological research approach was undertaken. Purposive sampling was employed to select participants for face‐to‐face semi‐structured in‐depth interviews. The interviews took place at a tertiary general hospital in Nanjing from January 2023 to February 2023.Twelve ICU transfer patients and their twelve spouses were interviewed. The data were then summarized, and themes were derived using the Colaizzi 7‐step analysis method.FindingsA total of four themes and eleven sub‐themes emerged from the analysis. The identified themes include positive coping (actively seeking solutions, and facing challenges together), negative coping (avoiding problems, displaying overprotective behaviour, and bearing the burden alone), difficulties and challenges (a lack of information, high physical and psychological stress, and significant financial burden), and needs and suggestions (strengthening transition care, fostering increased intimacy, and reducing negative emotions).ConclusionBoth patients and spouses experience physical and psychological stress during the transfer from the ICU to the ward. Therefore, any intervention developed for caregivers should be designed in a dyadic manner. Increasing dyadic coping skills may represent an important area for future research and intervention.Relevance to Clinical PracticeThis study provides valuable evidence to inform the formulation of a comprehensive dual disease management plan for ICU transfer patients and their spouses.
Synthetically induced Arabidopsis thaliana autotetraploids provide insights into the analysis of meiotic mutants with altered crossover frequency
Authors: Parra‐Nunez Pablo , Fernández‐Jiménez Nadia , Pachon‐Penalba Miguel , Sanchez‐Moran Eugenio , Pradillo Mónica , Santos Juan Luis 
Published: November 2023

Summary
Mutations affecting crossover (CO) frequency and distribution lead to the presence of univalents during meiosis, giving rise to aneuploid gametes and sterility. These mutations may have a different effect after chromosome doubling. The combination of altered ploidy and mutations could be potentially useful to gain new insights into the mechanisms and regulation of meiotic recombination; however, studies using autopolyploid meiotic mutants are scarce.
Here, we have analyzed the cytogenetic consequences in colchicine‐induced autotetraploids (colchiploids) from different Arabidopsis mutants with an altered CO frequency.
We have found that there are three types of mutants: mutants in which chiasma frequency is doubled after chromosome duplication (zip4, mus81), as in the control; mutants in which polyploidy leads to a higher‐than‐expected increase in chiasma frequency (asy1, mer3, hei10, and mlh3); and mutants in which the rise in chiasma frequency produced by the presence of two extrachromosomal sets is less than doubled (msh5, fancm). In addition, the proportion of class I/class II COs varies after chromosome duplication in the control.
The results obtained reveal the potential of colchiploid meiotic mutants for better understanding of the function of key proteins during plant meiosis. This is especially relevant considering that most crops are polyploids.