bluuebunny/crossref_metadata_2025_split huggingface dataset:
FBLIM1 mRNA is a novel prognostic biomarker and is associated with immune infiltrates in glioma
Authors: Deng Yifan , Zeng Kailiang , Wu Diancheng , Ling Yunzhi , Tian Yu , Zheng Yi , Fang Shumin , Jiang Xiaocong , Zhu Gang , Tu Yanyang 
Published: December 2023

Abstract
Glioma is the most common primary brain tumor. Filamin-binding LIM protein 1 (FBLIM1) has been identified in multiple cancers and is suspected of playing a part in the development of tumors. However, the potential function of FBLIM1 mRNA in glioma has not been investigated. In this study, the clinical information and transcriptome data of glioma patients were, respectively, retrieved from the TCGA and CGGA databases. The expression level of FBLIM1 mRNA was shown to be aberrant in a wide variety of malignancies. Significantly, when glioma samples were compared to normal brain samples, FBLIM1 expression was shown to be significantly elevated in the former. A poor prognosis was related to high FBLIM1 expression, which was linked to more advanced clinical stages. Notably, multivariate analyses demonstrated that FBLIM1 expression was an independent predictor for the overall survival of glioma patients. Immune infiltration analysis disclosed that FBLIM1 expression had relevance with many immune cells. The results of RT-PCR suggested that FBLIM1 expression was markedly elevated in glioma specimens. Functional experiments unveiled that the knockdown of FBLIM1 mRNA suppressed glioma cell proliferation. In general, we initially discovered that FBLIM1 mRNA might be a possible prognostic marker in glioma.
Assessing the significance of socioeconomic and demographic factors on COVID-19 cases in Turkey along with the development levels of provinces
Authors: Icoz Cenk , Ozcetin Erdener 
Published: December 2023

Abstract
In this study, we examine the spatial analysis of coronavirus disease 2019 (COVID-19) instances in Turkey. As a result, this analysis reveals that the geographic distribution of COVID-19 instances is associated with disparities in education, socioeconomic status, and population within individual provinces. By utilizing a composite indicator of development level based on provinces, we employ multivariate local Geary and multivariate local neighbor match tests to demonstrate the association between COVID-19 instances and the demographic and socioeconomic similarities or contrasts in provinces of Turkey. In addition, we provide an extremely randomized tree regression model to show how demographic and socioeconomic disparities affect COVID-19 instances. According to this model, the average household size, the proportion of the working-age population to the nonworking-age population, and the GDP per capita are the most important variables. The study’s main finding is that the important variables that were attained were also used to create an index for the degree of development in the Turkish regions. In other words, the same variables correlate with the degree of provincial development and the distribution of COVID-19 cases.
An Invention Shading Light to the Socio-History of Bonneuil Quarry Basin: The Roadheaders with Rotating Drill Bits
Authors: Lamesa Anaïs , Gély Jean-Pierre , Launay Guy 
Published: December 2023

Abstract
The Bonneuil quarry basin is located in the North-East of Paris; it played a role in the well-known stone trade for Paris and its surroundings in the nineteenth and the beginning of the twentieth centuries. Stonecutters of this area mainly used the extraction with the lance, a long iron spin bear by a scaffolding. This tool helped the quarrymen speed up their work allowing them to be competitive in trading. At the end of the 1930s, Martial Lefèvre, a wealthy owner of quarries in the Bonneuil’s basin, created a machine, roadheaders with rotating drill bits, following the movement of his quarrymen using the lance. The story of this machine was also involved in the Second World War and the occupation of France. Merging modern archaeology, history, and archaeology of technique, the aim of this paper is to explore the transition between hand tools and mechanical tools through the chaîne opératoire filter, a subject that is currently little studied. It also crossed the path of the delicate story of a small industry during one of the most events in France, the Second World War. Using it as an example, this article questions the status of these quarries during and after this main event.
Conduct politeness versus etiquette politeness: a terminological distinction
Authors: Jucker Andreas H. 
Published: December 2023

Abstract
This paper argues for a distinction between “conduct politeness” and “etiquette politeness”, where the former refers to the propriety of what people do and the latter to the decorum of how people do things. In everyday discourse, the distinction is often fuzzy, but as a second order distinction the terminology provides a useful analytical tool. In the history of politeness in English, a bifurcation into the two types of politeness can be observed in the eighteenth century, and today the distinction provides additional conceptual clarity of the changing theoretical focus during the three waves of politeness theory. After a review of the historical link between morals and manners, a brief case study focuses on their separation in the eighteenth century. A final discussion applies the distinction to the paradox that politeness is often seen as a positive thing that, unfortunately, is on the decline and as a negative thing because it is insincere, superficial and hypocritical.
An overview of the research trends on fiber-reinforced shotcrete for construction applications
Authors: Ahmad Waqas , Alabduljabbar Hisham , Deifalla Ahmed Farouk 
Published: December 2023

Abstract
In this study, data mining, followed by the scientometric analysis of fiber-reinforced shotcrete (FRS), was carried out for knowledge mapping, co-citations, and co-occurrence. The information needed for the analysis was retrieved from the Scopus search engine. Important publishing sources, keyword analysis, writers with the most contribution in citations and publications, the most-cited articles, and the regions most actively engaged in FRS research were identified throughout the data review process. Moreover, the need for FRS, the major constraints associated with their usage, and their possible solutions were discussed. The analysis of the bibliographic data showed that research publications on FRS progressed inconsistently till 2015, and over the past 6 years (2016–2021), publication numbers increased steadily, which exhibited the interest of academics in fiber-reinforced materials. The analysis of keywords in the field showed that the most common FRS research keywords are shotcreting, shotcrete, steel fibers, FRS, and fiber-reinforced materials. Keyword analysis showed that FRS is typically used for tunnel rock support and lining. Based on the review of relevant literature, research gaps have been identified, and future research has been suggested.
A Signaling Theory of the Online Consumer Review Policy
Authors: Kim Jeong-Yoo , Xu Wei 
Published: December 2023

Abstract
In this paper, we consider a two-period model of an experience good with a seller (informed player) and a consumer (uninformed player) in each period. In the model, we examine the seller’s decision about offering refunds for online reviews of his products, and each period consumer’s purchasing decision together with the first period consumer’s reviewing decision. Our main interest is whether a high-quality product seller offers a high amount or a low amount of cashback for an online review. We show that a lenient cashback policy for a review can be a signal of high quality of the product. Intuitively, a high-quality seller can offer a higher amount of cashback to a consumer who reviews, whether the review is positive or negative. This separation is possible mainly due to a difference in the second-period profits across types. We also briefly discuss the effect of the conditional review policy fostering fake reviews.
Die Missbrauchsverbote der Preisbremsengesetze (§ 39 StromPBG, § 27 EWPBG) im System des allgemeinen Wettbewerbsrechts
Authors: Wolf Maik 
Published: December 2023

Zusammenfassung
Mit den speziellen Missbrauchsverboten in den Preisbremsengesetzen für Strom, Gas und Wärme (§ 39 StromPBG, § 27 EWPBG) reagiert das Gesetz auf die besondere Gefahrenlage, die sich aus dem staatlichen Eingriff in den Preiswettbewerb durch die Preisbremse ergibt. Eine Nebenwirkung der Preisbremsen ist nämlich die Lähmung der von Preisspitzen entlasteten Verbraucher auf der Endkundenebene, die dadurch weniger Anreize haben, Preiserhöhungen durch einen Anbieterwechsel zu sanktionieren. Dies hat Auswirkungen auf die Verhaltensspielräume der Energieversorger gegenüber den Verbrauchern und auch auf den Wettbewerb auf den Energiemärkten. Vor diesem Hintergrund erscheint eine Aufsicht durch das Bundeskartellamt naheliegend, da dieses mit der Bekämpfung temporärer Marktmacht vertraut ist. Aus der Stellung der Missbrauchsverbote im System der Wettbewerbsordnung ergeben sich weitere Konsequenzen für ihre Auslegung und Anwendung
Zur Haftung von Geschäftsleitern für Schäden aus einer Kartellordnungswidrigkeit, insbesondere für Unternehmensgeldbußen
Authors: Friedl Markus J. 
Published: December 2023

Zusammenfassung
Mit seinem Urteil vom 27. Juli 2023 hat das OLG Düsseldorf als erstes deutsches Obergericht der ordentlichen Gerichtsbarkeit zum sog. Kartellinnenregress Stellung bezogen. Danach haftet ein Geschäftsleiter, der eine Kartellordnungswidrigkeit begangen hat, grundsätzlich für Schäden, die der Gesellschaft aufgrund der von ihm begangenen Kartellverstößen entstanden sind. Nach Ansicht des Oberlandesgerichts erstreckt sich die Haftung des Organs allerdings nicht auf die dem Unternehmen auferlegten Kartellbußgelder. Zu dieser Ansicht kommt das Gericht, indem es die Erstattung von Verbandsgeldbußen nach deutschem Kartellrecht von der Organhaftung der Geschäftsleiter ausnimmt und insoweit die § 93 Abs. 2 AktG, § 43 Abs. 2 GmbHG teleologisch reduziert. Unausgesprochen stellt sich das OLG Düsseldorf damit gegen den ebenfalls kurz zuvor ergangenen Hinweisbeschluss des LG Dortmund vom 21. Juni 2023, welches nachfolgend mit ergänzendem Hinweisbeschluss vom 14. August 2023 an seiner gegenteiligen Rechtsauffassung festhält. Im Folgenden soll vor dem Hintergrund des Meinungsstands zum Innenregress, insbesondere auch unter Darstellung der Auffassung des LG Dortmund (unter II.) das Urteil des OLG Düsseldorf dargestellt (unter III.) und bewertet (unter IV.) werden.
Frequency analysis of extreme air temperature events in an urban center in the Brazilian savanna
Authors: Rosso Rafaela Ferreira , Enoré Priscilla Tábida Silva , Souza Natallia Sanches e , Paula Diana Carolina de 
Published: December 2023

The increase in the planet's average air temperature in recent years has influenced the pattern of natural climatic phenomenons, with levels outside the normal range, the occurrence of prolonged dry periods, torrential rains and heat waves. Due to the climate crisis, extreme events have become increasingly frequent and more intense. With that in view, the aim of this article was to analyze the frequency of occurrence of extreme air temperature events between 2003 and 2023 in Cuiabá-MT-Brazil, as well as to understand the relationship between these extreme heat wave events and the occurrence and intensity of ENOS events. To this purpose, extreme events were analyzed using daily maximum air temperature data for the period from January 1, 2003 to October 31, 2023 obtained from the automated station of the National Meteorological Institute (INMET) located in Cuiabá - MT (CÓDA907), and ONI (Oceanic Niño Index) data. The results showed a significant increase of 86% in the occurrence of extreme events in 2020, compared to 2007, the year with the lowest number of occurrences. Therefore, it is extremely important that issues such as climate emergency, climate change and climate resilience are discussed as a means of public policy, preventing these increases from becoming even worse in frequency and/or intensity.
The metabasites from the Texel Unit (Austroalpine nappe stack): markers of Cretaceous intracontinental subduction and subsequent collision
Authors: Tropper Peter , Tribus Martina , Pomella Hannah , Habler Gerlinde 
Published: December 2023

Abstract
Eclogites in the Texel Unit (Austroalpine nappe stack; Eastern Alps, South Tyrol, Italy) represent the westernmost out-crops of the E-W striking Eoalpine High-Pressure Belt (EHB). East of the Tauern Window, the EHB forms part of a Cretaceous intracontinental south-dipping subduction/collision zone. The impetus of this contribution is to extend the geothermo-barometric data of the eclogites from the EHB using conventional geothermobarometry and multi-equilibrium calculations as well as Zr-in-rutile/titanite geothermometry and to put the P-T results of eclogites and amphibolites from the Texel Unit into the geodynamic framework. The investigated samples of this study are from the Spronser- and the Saltaus valleys (S-Tyrol) in the Austroalpine Texel Unit. The Texel Unit is composed mainly of paragneisses with minor intercalations of micaschists, orthogneisses, amphibolites and subordinately eclogites. The amphibolites from the Spronser valley contain the mineral assemblage amphibole + plagioclase + garnet + clinozoisite/epidote + quartz + titanite ± ilmenite ± rutile ± apatite ± calcite. Chemical zoning in plagioclase and amphibole shows two main growth stages: an older P-dominated stage (e.g. albite and barroisite cores) and a younger amphibolite-facies stage. The core of the amphiboles shows barroisite composition, the rim can be chemically classified as hornblende, edenite, tschermakite and pargasite. Geothermobarometric calculations with multi-equilibrium geothermobarometry (THERMOCALC v.3.21) yield temperatures of 600–654°C and pressures of 0.98–1.17 GPa for the same samples. The eclogites from the Saltaus valley contain the peak mineral assemblage omphacite + amphibole + garnet + clinozoisite/epidote + muscovite + quartz + titanite ± ilmenite ± rutile. Thermobarometric calculations, were performed in the system CaO-FeO-MgO-Na2O-Al2O3-FeO-SiO2-H2O with the assemblage clinopyroxene + garnet + amphibole + clinozoisite/epidote + muscovite + quartz ± H2O. The calculations involved an H2O-absent invariant point (mode-1 calculation) as well as two types of average P-T mode-2 calculations. The obtained average P-T H2O-absent mode 1 P-T conditions are 1.89 ± 0.18 GPa and 578 ± 60°C. Using the average P-T mode-2 two types of calculations were done: (1) calculations without amphiboles but with H2O present, which yield mean P-T conditions of 1.95 ± 0.28 GPa and 601 ± 55°C and (2) calculations with amphiboles but without H2O, which yield mean P-T conditions of 1.95 ± 0.26 GPa and 666 ± 77°C. Calculations using THERMOCALC v.3.33 yield similar results with slightly higher pressures of 0.3 GPa. Based on the present geothermobarometric data in conjunction with available mineral ages the eclogites represent the Eoalpine intracontinental subduction stage whereas the amphibolites reflect the subsequent, P-accentuated stage of decompression associated with the subsequent Eoalpine collisional stage.
Satisfactory Short‑Term Outcomes of Condylar‑Constrained Knee Implants in Primary Total Knee Arthroplasty
Authors: Saeed Ahmed , Zaghloul Ahmed , Abed Yasser youssef , Hammad Akram 
Published: December 2023

Background: This research set out to assess the functional prognosis of constrained condylar knee (CCK) in patients with severe intraoperative instability and/or coronal deformity undergoing primary total knee arthroplasty (TKA). Materials and methods: A prospective cohort study including 25 knees (21 cases) who underwent primary TKA using CCK implants. Senior surgeon operated all patients during 2020/2021 and followed clinically and radiographically at three, six and 12 months and 2 years postoperative. All cases were implanted with a single-design, second-generation CCK implant with a mean follow-up of 2 years. Results: The current research involved 25 knees (21 patients) with mean age 62.8 ± 12.2 years and most of the included patients were females (19; 76%). Preoperatively, valgus was demonstrated in six patients (24%) while varus was reported in 19 patients (76%) with mean preoperative Valgus/Varus angle 24.4 ± 9.9. Mean preoperative Knee Society Score (KSS) was 13.2 ± 2.7, mean preoperative functional KSS was 23.8 ± 19.2 and mean preoperative range of movement (ROM) was 107 ± 19.2. After 6 months, mean values of KSS was 86.2 ± 7.59. After 1 year, 2 years & over 2 years, mean values of KSS were 86.2 ± 7.6, 86.2 ± 7.5, 86.3 ± 7.7 respectively. Degree of change in KSS before and after the operation was 69.1 ± 20.9. Mean values of late functional KSS was 62.5 ± 23.3. Degree of change in functional KSS before and after the operation was 36.8 ± 19.1. Postoperative ROM mean value was 120 ± 6.9 with degree of change 12.8 ± 6.3. Three cases reported postoperative complications; one cellulitis, one anterior femoral notching and one peroneal nerve injury. KSS increased from baseline to early postoperative with statistically significant variances (p< 0.001) however, no statistically significant changes were discovered in KSS from early postoperatively to 2 years of follow up. Conclusion: Primary TKA utilizing CCK implants in cases with severe coronal abnormalities and/or intraoperative instability had a good short-term survival rate, on par with less limited implants. With positive clinical and radiological results, CCK implants can be thought of as a good alternative in some instances. It is important to exercise caution while utilizing an elevated level of restraint, since less restricted implants should be preferred.
Evaluation of the quality of endodontic access cavities made by students of the institute of dentistry and stomatology of Dakar
Authors: Ndiaye Diouma , Seck Anta , Kouakou Kouadio Florent , Kaboré Wendpoulomdé Aimé Désiré , Bane Khaly 
Published: December 2023

The aim of this study was to evaluate the technical quality of endodontic access cavities performed by M1 and M2 students during the clinical teaching of endodontics. The study population consisted of patients who came for consultation in the clinic of the Conservative Odontology-Endodontics Department of the Institute of Odontology and Stomatology of Dakar. The inclusion criteria were for teeth for which endodontic treatment was indicated and an access cavity was performed for the first time and exclusively by a student as part of the clinical training in endodontics. A survey form was drawn up containing the following headings: contour shape, visibility of canal entrances, body shape, and accidents along the way (stop, perforations, or flattening of the pulp floor). The chi-squared test was used to compare quantitative and qualitative variables and the significance level was set at p&#60;0.05.A total of 139 endodontic access cavities were made by students (56.8% by Master 2 (M2) students and 43.2% by Master 1 (M1) students). Of these, 35% of the access cavities made by M1 students were acceptable versus 44% acceptable for M2. The difference was statistically significant (p&#60;0.05).It appears from this study that the rate of technically acceptable access cavities made by the students of the Institute of Odonto-Stomatology of Dakar was insufficient. Thus, modifications must be made in the preclinical and clinical training program of Endodontics students.
An in-vitro comparison of bond strength of three different root end filling materials with Universal testing machine
Authors: Goyal Vandana , Garg Iyana , Kaur Parminder , Tomar Ankita 
Published: December 2023

Bacterial infection is widely known cause of apical periodontitis. Failure of conventional root canal treatment indicates the periapical surgery, this procedure requires root end resection. For the long term success of periapical surgery, root end filling materials are used. To compare the push-out bond strength of Portland cement, ProRoot MTA and Biodentine used as root-end filling materials using Universal Testing Machine. From the middle part of each root, three dentinal slices were made to produce 93 slices which were divided into 3 groups. In Group A: ProRoot MTA, In Group B: Biodentine and In group C: Portland cement were used and were further divided in subgroups based on soaking time in PBS solution i.e. 24hrs and 7 days before assessing the push out bond strength using Universal Testing Machine. The mode of bond failure of material to root dentin was analyzed using microscope. Data was analyzed using ANOVA and post-hoc tukey’s test. After 24hrs, there was statistically non-significant difference but After 7 days, ProRoot MTA showed significantly higher bond strength as compared to other tested groups. While analyzing the mode of bond failure, ProRoot MTA had adhesive failure, Biodentine had cohesive failure and Portland cement had mixed type of bond failure. All the tested materials showed comparable bond strength but ProRoot MTA had highest bond strength to root dentin among the other tested materials.
Comparative evaluation of a novel herbal formulation with commercially available synthetic solution in cleaning used endodontic instruments: An in vitro study
Authors: Chhabra Naveen , Krupa Desai 
Published: December 2023

The study aimed to compare the cleaning effectiveness of a novel herbal solution with commercially available cleaning solution in eliminating biological debris from the surfaces of used endodontic instruments.Thirty freshly extracted human single rooted premolars were decoronated to the standardized length. The root canals were prepared using rotary files till master apical size 35 (0.04 taper) and distilled water as irrigant. Used master apical files were assessed under scanning electron microscope (SEM) at 40x magnification at apical, middle and coronal third of working end independently for debris accumulation on the cutting surface of file and scored. All the specimens were randomly divided according to the group distribution as follows: Group 1: Synthetic cleaning solution, Group 2: Novel herbal cleaning solution. All files were immersed in the solution for five minutes according to the allocated groups and wiped using sterile gauze piece with one complete rotation covering all the flutes. Each used file was again examined under SEM at 40x at apical, middle and coronal third levels by an independent blinded evaluator and the residual debris were scored. The collected data were subjected to independent sample t test (p&#60;0.05).Statistically significant difference was observed amongst the two groups at middle and apical third of endodontic files (p &#60; 0.05), however, difference at coronal third level was insignificant (p &#62; 0.05).The herbal solution effectively removed the clogged debris from endodontic files as compared to commercial formulation.