bluuebunny/crossref_metadata_2025_split huggingface dataset:
Strategi Peningkatan Layanan Ideal Manajemen Pernikahan di KUA Kecamatan Jatisempurna Kota Bekasi
Authors: Supriyadi Imam , Sulaeman Eman 
Published: February 2024

Akad Nikah adalah peristiwa pernikahan yang menjadi momentum sakral setiap muslimin dan muslimah yang telah siap membangun keluarga. Secara umum pelaksanaan akad nikah adalah di masjid-masjid atau di gedung-gedung yang bersamaan dengan pelasksanaan acara walimah atau resepsi pesta pernikahan, hanya berbeda waktu jam pelaksanaan. Pemilihan hari pelaksanaan akad nikah hampir selalu bersamaan hari dengan acara walimah atau resepsi pesta pernikahan, yaitu akhir pekan (Sabtu dan Minggu) atau hari libur. Di satu sisi hal tersebut tidak dilarang atau menyalahi aturan agama. Namun terdapat dampak yaitu turunnya Standar Layanan KUA, dalam penelitian ini adalah KUA Jatisampurna Kota Bekasi, yaitu berupa kekecewaan calon pengantin yang tidak mendapat layanan pelaksanaan peristiwa pernikahan atau tertunda, karena waktu pelaksnaan terbatas di hari-hari yang disukai. Tujuan Penelitian ini adalah untuk membuat solusi atas permasalahan tersebut yaitu membuat Strategi Peningkatan Layanan dengan memanfaatkan hari dan jam kerja (Senin s.d Jum’at) di mana petugas penghulu justru sangat sedikit atau sempat kososng tidak melayani peristiwa pernikahan. Penambahan waktu layanan peristiwa pernikahan ini sangat bermanfaat untuk menambah jumlah pernikahan sekaligus mencegah perbuatan kawin di luar nikah karena tidak terlayani oleh KUA. Metode yang digunakan dalam penelitian ini adalah Kualitaitf dan Analisa Deskriptif. Adapun data yang digunakan adalah Data Primer dari KUA Kecamatan Jarisampurna Kota Bekasi berupa data-data pernikahan, perceraian, dan rujuk, serta wawancana. Dalam pelaksanaan strategi ini perlu dikoordinasikan dan disosialisasikan dengan pihak-pihak terkait di lingkup Kecamatan Jatisampurna Kota Bekasi. Saran dari pemelitian ini adalah jika KUA Jatisampurna telah berhasil menjalankannya, dapat mengusulkan ke Kemenag RI sehingga bisa diterapkan di seluruh KUA.
Kata kunci: Layanan Ideal, Manajemen Pernikahan, KUA Jatisampurna Kota Bekasi
Поширеність хвороб і шкідників дерев роду Ulmus у лісових смугах уздовж автошляху Київ – Харків
Authors: Кузнецова О. А. , Туренко В. П. , Товстуха О. В. , Давиденко К. В. 
Published: February 2024

У червні – вересні 2023 р. на 96 пробних площах обстежено 2250 дерев роду Ulmus у лісових смугах уздовж автомобільного шляху М 03, який проходить територією Київської, Полтавської та Харківської областей. Представництво U. glabra зменшувалося від Київської до Харківської областей. U. laevis найбільшою мірою представлений у Полтавській області, а U. pumila – у Харківській. Основними чинниками ослаблення в’язів були бактеріоз (у середньому за пробними площами 10,6–13,4 % дерев) і голландська хвороба (4–10,2 % дерев), меншою мірою – окоренкові гнилі (2,5–4,5 % дерев). У межах доступної для огляду висоти стовбурів поселення короїдів виявлено на 4,5–9,9 % дерев. Частка уражених дерев залежала від виду в’яза та розташування фрагмента насаджень. Найбільш уразливим виявився U. pumila, стосовно якого визначено 47,2; 32 і 33 % дерев із наявністю всіх типів уражень у фрагментах насадження в межах Київської, Полтавської та Харківської областей відповідно, зокрема уражено голландською хворобою 11,3; 10,7 і 9,3 % відповідно. Уперше в регіоні дослідження молекулярними методами підтверджено наявність виду Ophiostoma novo-ulmi subsp. americana та його агресивного гібрида Ophiostoma novo-ulmi subsp. americana ? novo-ulmi – збудників голландської хвороби в’язів. Бактеріоз усіх видів в’язів був найбільшою мірою поширений у фрагменті насаджень у межах Київської області, найменшою – у межах Харківської області.
Комплексне оцінювання потомств клонових насінних плантацій сосни звичайної за ростовими характеристиками та ознаками стійкості в умовах Лісостепу Харківської області
Authors: Дишко В. , Ошако Т. , Боровик П. 
Published: February 2024

Обстежено 20-річні сортовипробні культури сосни звичайної (Pinus sylvestris L.), представлені насіннєвими потомствами клонових насінних плантацій та загального збору насаджень державних підприємств Волинської, Київської і Харківської областей. У кожному варіанті відібрано 20 дерев, які дослідили за ростовими характеристиками (висотою, діаметром), прямизною стовбура, станом, а також за ознаками, пов’язаними зі стійкістю сосни до ураження кореневою губкою (масою насіння, щільністю розташування хвої на пагонах, параметрами провідної системи хвої на серединному перерізі, шириною шарів пізньої та ранньої деревини, інтенсивністю виходу живиці з мікропоранень). Здійснено комплексне оцінювання потомств клонових насінних плантацій, представлених на ділянці, за стандартною методикою, яка передбачає оцінювання за ознаками росту, прямизною стовбура і станом, а також за запропонованою модифікованою шкалою, з урахуванням потенціалу стійкості дерев до ураження кореневою губкою. Під час оцінювання насіннєвого потомства клонових насінних плантацій за стандартною методикою лідерами визначили походження переважно зі сходу України, тоді як за модифікованою - з усіх трьох регіонів. Застосування ознак стійкості під час комплексного оцінювання потомств плюсових і найкращих дерев та популяцій дасть змогу запропонувати нові сорти лісових деревних видів для створення насаджень із підвищеною стійкістю.
Between Anthropogenic Influence and Resource Management: Impacts of Risks and Preservation Strategies in the Ikopa Watershed, Madagascar
Authors: Fidelio Arnold Ulrich  , Razanamparany Bruno  , Rejo Robert  , Ratiarimananjatovo Narindra  , Andrianjary Myriam  , Robijaona Rahelivololoniaina Baholy  
Published: February 2024

The impacts of anthropogenic risks on water resource management underscore the necessity for a careful and adaptable approach to ensure long-term sustainability. In the Ikopa Watershed in Madagascar, numerous human activities present significant challenges. Water quality is impacted by pollution resulting from agricultural practices. Uncontrolled deforestation intensifies watershed degradation, jeopardizing the availability of water resources. Rapid urbanization and escalating human activities further contribute to the deterioration of water quality. The hypothesis posits that responsible exploitation of natural resources contributes to the preservation and sustainability of water resources in the Ikopa Watershed. This study concentrates on investigating potential anthropogenic risks that influence resource degradation and the perception of mitigation measures. The main objective of this section is to assess the anthropogenic risk factors contributing to water resource degradation in the watershed. The study employs change detection studies through remote sensing and GIS approaches, complemented by social analysis. This methodology aims to identify potential anthropogenic risks affecting responsible water resource management, along with an exploration of local mitigation strategies. The results underscored potential risks faced by the local population in the watershed, including challenges associated with agriculture, urbanization, inadequate drainage network management, and high population density. Binary logistic regression analysis reveals significant connections between anthropogenic risks and the mitigation strategies adopted by local communities in the Ikopa Watershed. The findings indicate that specific characteristics of degradation or local interventions can either positively or negatively influence the adoption of these strategies.
Sobre el cortante en elementos sin estribos y la aplicación de métodos energéticos a la luz de 30 años de observaciones experimentales
Authors: Bentz Evan C. , Foster Stephen J. 
Published: February 2024

En un artículo reciente en Structural Concrete, los autores Dönmez y Bažant explican que las bases teóricas de las ecuaciones del Código Modelo 2010 para el cortante en una dirección y el punzonamiento no están suficientemente fundamentadas a nivel teórico y, en su lugar, deberían utilizar una ley energética de efecto tamaño en su formulación para ajustarse al comportamiento. Para respaldar esta afirmación, se presentaron simulaciones de elementos finitos. En este artículo se cuestiona la hipótesis básica de que un método energético debe gobernar el fallo por cortante de vigas sin estribos. Se demuestra que estas preguntas se basan en el comportamiento de endurecimiento de ensayos de engranamiento de áridos y en la incapacidad de localizar deformaciones de deslizamiento durante el fallo por cortante. Además de estos argumentos teóricos, se realizaron análisis de elementos finitos con un modelo constitutivo energético pero que también trabaja adecuadamente al modelar el engranamiento de áridos, un aspecto que parece estar ausente en los análisis de Dönmez y Bažant. Estos nuevos resultados modelan mejor los resultados de los ensayos y confirman que el engranamiento de áridos es importante para explicar la resistencia al cortante y, por tanto, el efecto tamaño en el cortante en elementos esbeltos. Como tal, cualquier preocupación sobre la seguridad de las ecuaciones de cortante del Código Modelo parece injustificada.
Traducido por Lisbel Rueda del artículo original publicado por Wiley en la revista Structural Concrete: Bentz EC, Foster SJ. On shear in members without stirrups and the application of energy-based methods in light of 30 years of test observations. Structural Concrete. 2019; 20: 1481–1489. https://doi.org/10.1002/suco.201900224
Peningkatan Keterampilan Motorik Halus Melalui Kegiatan Menganyam Pada Anak Usia 5-6 Tahun
Authors: Putri Hana Nabila , Nurmiyanti Leni 
Published: February 2024

The purpose of this study was to stimulate children to improve fine motor skills in group B children at ABA Al Jabbar Kelapa Dua Kindergarten by using weaving activities.Â This research is a classroom action research. The research was carried out in two cycles, with each cycle consisting of planning, implementing actions, observing and reflecting. The research subjects were students from the ABA Al-Jabbar Kelapa Dua Kindergarten, totaling 12 children. Sources of data obtained from the Principal, teachers and parents. Data collection techniques are observation, interviews and documentation.Â The results of this study indicate that through weaving activities can improve fine motor skills in children. The increase occurred during the implementation of the first cycle, the children had started to participate in weaving activities although they had not increased. In the implementation of cycle II, the increase in children's activities increased because almost all children were able to do weaving activities according to the directions given.
Feasibility and tolerability of eribulin-based chemotherapy versus other chemotherapy regimens for patients with metastatic triple-negative breast cancer: a single-centre retrospective study
Authors: Huang Weiwei , Wang Chenxi , Wang Lili , Shen Yangkun , Chen Qi , Huang Zhijian , Liu Jian , Lin Xiaoyan , Wu Fan , Chen Xinhua , Li Nani , Hong Yi , Chen Mulan , Li Jieyu , Huang Chuanzhong 
Published: February 2024

Background: Patients with Triple-negative breast cancer (TNBC) face a poor prognosis and limited therapeutic options. Current data on eribulin usage to treat TNBC is scarce. Therefore, we sought to compare the feasibility and tolerability of eribulin-based regimens with other chemotherapy regimens in patients with TNBC.Method: This retrospective study was conducted at Fujian Medical University Cancer Hospital and included 159 patients with TNBC enrolled between October 2011 and January 2023. Patients underwent treatment with eribulin-based and other chemotherapy regimens. The study’s primary endpoints were progression-free survival (PFS) and overall survival (OS), while its secondary endpoint was objective response rate (ORR), disease control rate (DCR), and safety. Tumour response was assessed using RECIST V.1.1 criteria.Results: Of the 159 participants in the study, 42 individuals (26.4%) received treatment with eribulin, whereas 117 participants (73.6%) were administered alternative chemotherapy regimens, which included nab-paclitaxel-based therapy (n = 45) and platinum-based therapy (n = 51). The follow-up period for all patients ended on 31 December 2022, and the median follow-up time was 18.3 months (range:0.7–27.5). Following propensity score matching (PSM), eribulin-based treatment resulted in longer median progression-free survival compared to platinum-based (hazard ratio (HR) = 0.41, p = 0.006), nab-paclitaxel-based (hazard ratio = 0.36, p = 0.001) and other chemotherapy (HR = 0.39, p &lt; 0.001). Also, eribulin induced a remarkable prolongation of the median overall survival duration in all three comparative groups. The group receiving eribulin treatment showed significantly reduced incidences of any grade of anaemia, peripheral neuropathy, nausea and vomiting, and hair loss compared to other chemotherapy groups.Conclusion: For the salvage treatment of advanced TNBC, treatment with eribulin produced longer median PFS and OS than other chemotherapy regimens, with a well-tolerated safety profile. Therefore, further investigation of eribulin-based treatment in larger randomized trials for patients with advanced TNBC is warranted.
Genetic variation of FcγRIIa induces higher uptake of Leishmania infantum and modulates cytokine production by adherent mononuclear cells in vitro
Authors: Catarino Jonatas da Silva , Oliveira Rafael Faria de , Silva Marcos Vinicius , Sales-Campos Helioswilton , de Vito Fernanda Bernadelli , Silva Djalma Alexandre Alves da , Naves Lucila Langoni , Oliveira Carlo José Freire , Rodrigues Denise Bertulucci Rocha , Rodrigues Virmondes 
Published: February 2024

IntroductionSingle nucleotide variations (SNVs) are specific genetic variations that commonly occur in a population and often do not manifest phenotypically. However, depending on their location and the type of nucleotide exchanged, an SNV can alter or inhibit the function of the gene in which it occurs. Immunoglobulin G (IgG) receptor genes have exhibited several polymorphisms, including rs1801274, which is found in the FcgRIIa gene. The replacement of A with T results in a Histidine (H) to Arginine (R) substitution, altering the affinity of the IgG receptor for IgG subtypes and C-reactive protein (CRP). In this study, we analyzed rs1801274 and its functional implications concerning L. Infantum uptake and cytokine production.MethodsWe genotyped 201 individuals from an endemic area for visceral leishmaniasis to assess the presence of rs1801274 using Taqman probes for a candidate gene study. Additionally, we included seventy individuals from a non-endemic area for a functional study. Subsequently, we isolated and cultivated one-week adherent mononuclear cells (AMCs) derived from the peripheral blood of participants residing in the non-endemic region in the presence of L. infantum promastigotes, with and without antigen-specific IgG and/or CRP. We analyzed the rate of phagocytosis and the production of nitric oxide (NO), tumor necrosis factor (TNF)-a, interleukin (IL)-10, IL-12 p70, IL-1b, IL- 6, and IL-8 in the culture supernatants.Results and discussionIn participants from the endemic region, the A/G (H/R isoform) heterozygous genotype was significantly associated with susceptibility to the disease. Furthermore, SNVs induced a change in the phagocytosis rate in an opsonin-dependent manner. Opsonization with IgG increased the production of IL-10, TNF-a, and IL-6 in AMCs with the H/R isoform, followed by a decrease in NO production. The results presented here suggest that the rs1801274 polymorphism is linked to a higher susceptibility to visceral leishmaniasis.
Promoting the process of determining brain death through standardized training
Authors: Su Yingying , Zhang Yan , Ye Hong , Chen Weibi , Fan Linlin , Liu Gang , Huang Huijin , Gao Daiquan , Zhang Yunzhou 
Published: February 2024

ObjectiveThis study aims to explore the training mode for brain death determination to ensure the quality of subsequent brain death determination.MethodsA four-skill and four-step (FFT) training model was adopted, which included a clinical neurological examination, an electroencephalogram (EEG) examination, a short-latency somatosensory evoked potential (SLSEP) examination, and a transcranial Doppler (TCD) examination. Each skill is divided into four steps: multimedia theory teaching, bedside demonstration, one-on-one real or dummy simulation training, and assessment. The authors analyzed the training results of 1,577 professional and technical personnel who participated in the FFT training model from 2013 to 2020 (25 sessions), including error rate analysis of the written examination, knowledge gap analysis, and influencing factors analysis.ResultsThe total error rates for all four written examination topics were &lt; 5%, at 4.13% for SLSEP, 4.11% for EEG, 3.71% for TCD, and 3.65% for clinical evaluation. The knowledge gap analysis of the four-skill test papers suggested that the trainees had different knowledge gaps. Based on the univariate analysis and the multiple linear regression analysis, among the six factors, specialty categories, professional and technical titles, and hospital level were the independent influencing factors of answer errors (p &lt; 0.01).ConclusionThe FFT model is suitable for brain death (BD) determination training in China; however, the authors should pay attention to the professional characteristics of participants, strengthen the knowledge gap training, and strive to narrow the difference in training quality.
Total cucurbitacins from Herpetospermum pedunculosum pericarp do better than Hu-lu-su-pian (HLSP) in its safety and hepatoprotective efficacy
Authors: Liu Wen-Ya , Xu Di , Hu Zi-Yun , Meng Hui-Hui , Zheng Qi , Wu Feng-Ye , Feng Xin , Wang Jun-Song 
Published: February 2024

The pericarp of Herpetospermum pedunculosum (HPP) has traditionally been used for treating jaundice and hepatitis. However, the specific hepatoprotective components and their safety/efficacy profiles remain unclear. This study aimed to characterize the total cucurbitacins (TCs) extracted from HPP and evaluate their hepatoprotective potential. As a reference, Hu-lu-su-pian (HLSP), a known hepatoprotective drug containing cucurbitacins, was used for comparison of chemical composition, effects, and safety. Molecular networking based on UHPLC-MS/MS identified cucurbitacin B, isocucurbitacin B, and cucurbitacin E as the major components in TCs, comprising 70.3%, 26.1%, and 3.6% as determined by RP-HPLC, respectively. TCs treatment significantly reversed CCl4-induced metabolic changes associated with liver damage in a dose-dependent manner, impacting pathways including energy metabolism, oxidative stress and phenylalanine metabolism, and showed superior efficacy to HLSP. Safety evaluation also showed that TCs were safe, with higher LD50 and no observable adverse effect level (NOAEL) values than HLSP. The median lethal dose (LD50) and NOAEL values of TCs were 36.21 and 15 mg/kg body weight (BW), respectively, while the LD50 of HLSP was 14 mg/kg BW. In summary, TCs extracted from HPP demonstrated promising potential as a natural hepatoprotective agent, warranting further investigation into synergistic effects of individual cucurbitacin components.
Health behavior profiles and association with mental health status among US active-duty service members
Authors: Olapeju Bolanle , Hendrickson Zoé Mistrale , Shanahan Patrice , Mushtaq Omar , Ahmed Anwar E. 
Published: February 2024

IntroductionThis study investigated the clustering of health behaviors among US active duty servicemembers (ADSM) into risk profiles and explored the association between these profiles with ADSM sociodemographic characteristics and mental health status.MethodsThis study utilized secondary data from the 2018 Health Related Behaviors Survey (HRBS), a Department of Defense (DoD) self-administered online survey. Health behaviors included physical activity, screen use, sleep habits, tobacco/substance use, alcohol drinking, preventive health care seeking and condom use at last sex/having multiple sexual partners. Past-year mental health status was measured using the Kessler Screening Scale for Psychological Distress (K6). Latent class analysis (LCA) on health behaviors was used to cluster ADSMs into risk profiles. Multivariable logistic model was used to examine whether ADSM characteristics and mental health status were associated with ADSMs' risk profiles.ResultsThe LCA identified a four-class model that clustered ADSMs into the following sub-groups: (1) Risk Inclined (14.4%), (2) High Screen Users (51.1%), (3) Poor Sleepers (23.9%) and (4) Risk Averse (10.6). Over a tenth (16.4%) of ADSMs were categorized as having serious psychological distress. Being male, younger, less educated, in the Army, Marine Corps or Navy were associated with higher odds of being Risk Inclined (AOR ranging from 1.26 to 2.42). Compared to the reference group of Risk Adverse ADSMs, those categorized as Risk Inclined (AOR: 8.30; 95% CI: 5.16–13.36), High Screen Users (AOR: 2.44; 95% CI: 1.56–3.82) and Poor Sleepers (AOR: 5.26; 95% CI: 3.38–8.19) had significantly higher odds of having serious psychological distress.DiscussionStudy findings suggest opportunities to tailor behavioral and health promotion interventions for each of the distinct risk profiles. For example, ADSM described as Risk Inclined may benefit from preventive mental health services. Solutions for ADSM described as Poor Sleepers may include education on sleep hygiene; instituting duty schedules; and shifting military cultural norms to promote sleep hygiene as a pathway to optimal performance and thus military readiness. ADSM with low-risk behavior profiles such as those described as Risk Averse may prove beneficial in the roll-out of interventions as they act as peer-educators or mentors.
A Low-Noise Amplifier for Submarine Electric Field Signal Based on Chopping Amplification Technology
Authors: Liu Fenghai , Chun Shaoheng , Chen Rujun , Xu Chao , Cao Xun 
Published: February 2024

In the exploration of ocean resources, the submarine electric field signal plays a crucial role through marine electromagnetic methods. However, due to the field signal’s low-frequency and weak characteristics, it often encounters interference from the instrument’s own 1/f noise during its acquisition. To address this issue, we developed a low-noise amplifier for the submarine electric field signal based on chopping amplification technology. This amplifier utilizes low-temperature electronic components to adapt to the cold submarine environment and enhances its independence by incorporating a square wave generator. Additionally, we conducted simulations and experimental tests on the designed chopper amplifier circuit, evaluating the equivalent input voltage noise spectrum (EIVNS) and the frequency response within 1 mHz~100 Hz. The experimental results indicate that the amplifier designed in this study achieves sufficiently low noise 2 nV/√Hz@1 mHz, effectively amplifying the submarine electric field signal measured with the electric field sensor.