bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hemorheology and Inflammatory Marker Changes in Patients with Acute Ischemic Stroke after Intravenous Thrombolysis with Mechanical Thrombectomy
Authors: Wu Li , Shi Peng , Zhao Yujie , Shao Di , Wu Hongliang 
Published: December 2023

Objective: To investigate hemorheology and inflammatory marker changes after treatment for acute ischemic stroke (AIS) using intravenous thrombolysis (IVT) with mechanical thrombectomy (MT).
Methods: We retrospectively reviewed clinical records of patients with AIS (n=83) treated in The First Affiliated Hospital of Bengbu Medical College between January 2021 and December 2022 (n=83). The control group consisted of 38 patients who underwent IVT alone and the observation group consisted of 45 patients who underwent IVT with MT. We compared differences in mean variables related to hemorheology, inflammatory markers, and total efficacy between the two groups.
Results: We found that hemorheology values (plasma viscosity [PV], whole blood viscosity [WBV], fibrinogen [FIB], and hematocrit [HCT]), and the levels of inflammatory markers (tumor necrosis factor α [TNF-α] and interleukin-6 [IL-6]) were higher in the control group than in the observation group after treatment (P<0.05). In addition, the total efficacy of the observation group (93.3%) was higher than that in the control group (76.3%; P=0.016).
Conclusions: The clinical efficacy of combined IVT and MT in the treatment of AIS is superior to IVT alone, improving levels of hemorheology and inflammatory markers in patients with AIS.
doi: https://doi.org/10.12669/pjms.40.3.8396
How to cite this: Wu L, Shi P, Zhao Y, Shao D, Wu H. Hemorheology and Inflammatory Marker Changes in Patients with Acute Ischemic Stroke after Intravenous Thrombolysis with Mechanical Thrombectomy. Pak J Med Sci. 2024;40(3):---------. doi: https://doi.org/10.12669/pjms.40.3.8396
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
THE COMPONENT COMPOSITION OF THE PROJECT-BASED LEARNING METHODOLOGY IN THE CONTEXT OF THE EDUCATIONAL STANDARD (USING THE EXAMPLE OF A GENERAL BIOLOGY COURSE)
Authors: Shekhmirzova Andzhelika M. , Gribina Lyudmila V. , Tuguz Fatima A. 
Published: December 2023

The article reveals the essence of project-based learning through the allocation of the basic principle of its definition – the principle of independent acquisition of knowledge by students in the course of solving subject practical problems using various subject knowledge (including integrated). On its basis, the substantiation of the component composition of the methodology of project training at the level of general education is presented. The relevance of the research lies in the possibility of its implementation in the educational process to achieve the planned results of the federal state educational standard in the form of subject and meta-subject (UUD) competencies formed by students. On the example of the general biology course, the effectiveness of the implementation of the component composition of the project training methodology is shown. Its justification is based on the presented results of experimental work.
Purpose: substantiation of the component composition of the project training methodology in the form of a system of goals, content, principles, approaches, methods, didactic tools, diagnostics and monitoring of the levels of subject and metasubject competencies formed in students.
Methodology: the article presents a set of theoretical and empirical methods of pedagogical research used in the identification, justification and implementation of the component composition of the methodology of project-based learning in the practice of teaching.
Results: improving the effectiveness of the educational process in the formation of subject and meta-subject (UUD) competencies of students in the federal state educational standard by applying the component composition of the project-based learning methodology.
Practical implications: the results of the study can be used by subject teachers in the implementation of the required educational results according to the federal state educational standard and taken into account in the development of educational programs at the school level by administrative and managerial personnel.
APPROACHES TO INCREASING MOTIVATION FOR LEARNING ACTIVITIES OF MEDICAL UNIVERSITY STUDENTS
Authors: Uranova Valeria V. , Starikova Alla A. , Bliznyak Olga V. 
Published: December 2023

Introduction. This article is devoted to the study of the influence of the teacher’s activity on the level of motivation of students of higher educational institutions.
Purpose: to study the characteristics of the motivation of students studying in the specialty 33.05.01. “Pharmacy”.
Materials and methods. The study is based on a preliminary study and analysis of data obtained by domestic scientists and presented in the sources of psychological and pedagogical literature. The implementation of the tasks set was carried out in the course of a sociological survey. The results were processed using the methods of mathematical statistics.
Results. A technology has been developed to increase the motivational level of students in the form of an algorithm, introduced into the work of the teaching staff of the Department of Chemistry of the Faculty of Pharmacy in the preparation of future pharmacists.
Scope. The algorithm of professional orientation of students developed by the authors can be used when teaching students in a higher educational institution. The applicability of the obtained statistically significant results as a basis for further work on increasing students’ motivation for the implementation of educational activities is substantiated.
Conclusion. It was revealed that changes in the deep motives of students occurred when the teaching staff used new methods that make it possible to modernize the standard learning process, taking into account the interests and psychological characteristics of future pharmacists.
Automated Semantic Annotation Deploying Machine Learning Approaches: A Systematic Review
Authors: Chang Wee Chea , Sangodiah Anbuselvan 
Published: December 2023

Semantic Web is the vision to make Internet data machine-readable to achieve information retrieval with higher granularity and personalisation. Semantic annotation is the process that binds machine-understandable descriptions into Web resources such as text and images. Hence, the success of Semantic Web dependson the wide availability of semantically annotated Web resources. However, there remains a huge amount of unannotated Web resources due to the limited annotation capability available. In order to address this, machine learning approaches have been used to improve the automation process. This Systematic Review aims to summarise the existing state-of-the-art literature to answer five Research Questions focusing on machine learning driven semantic annotation automation. The analysis of 40 selected primary studies reveals that the use of unitary and combination of machine learning algorithms are both the current directions. SupportVector Machine (SVM) is the most-used algorithm, and supervised learning is the predominant machine learning type. Both semi-automated and fully automated annotation are almost nearly achieved. Meanwhile, text is the most annotated Web resource; and the availability of third-party annotation tools is in-line with this. While Precision, Recall, F-Measure and Accuracy are the most deployed quality metrics, not all the studies measured the quality of the annotated results. In the future, standardising quality measures is the direction for research.
Wyobrażenia i wiara w Boga dorosłych katolików w Polsce w drugiej połowie XX wieku i obu dekadach XXI wieku. Na podstawie wyników badań socjologicznych
Authors: Baniak Józef 
Published: December 2023

In this article I present the attitude of adult Catholics in Poland in the second half of the 20th century and in both decades of the 21st century towards Theoentrical dogmas and the indicators of their faith in the religious meanning of these dogmas. The basis for the analysis of the attitude of adult Roman Catholics in Poland to these dogmas of the Christian faith are the results of sociological research carried out the turn of the 20th and 21st centuries. These studies showed that in the second half of the 20th century, a much greater percentage of adult Catholic in Poland accepted Theocentric dogmas and declared their faith in their religious mening than in both decades of the 21st century.
Determination of ertapenem in plasma and ascitic fluid by UHPLC-MS/MS in cirrhotic patients with spontaneous bacterial peritonitis
Authors: Rigo-Bonnin Raúl , Amador Alberto , Núñez-Gárate María , Mas-Bosch Virgínia , Padullés Ariadna , Cobo-Sacristán Sara , Castellote José 
Published: December 2023

Abstract

Objectives
Spontaneous bacterial peritonitis is a frequent severe complication in cirrhotic patients with ascites. Carbapenem antibiotics are currently the treatment of choice for patients with hospital-acquired or healthcare-related infections. However, there is limited evidence available on the efficacy of ertapenem in cirrhotic patients with spontaneous bacterial peritonitis. As a result, the pharmacokynetics and pharmacodynamics of this antibiotic are still unknown. The objective of this study was to develop and validate measurement procedures based on liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) to determine ertapenem concentrations in plasma and ascitic fluid.

Methods
Samples were pretreated by acetronile protein-precipitation. Chromatographic separation is performed on a C18 reversed-phase Acquity®-UPLC®-BEHTM column (2.1 × 100 mm id, 1.7 µm) using a non-linear gradient of water/acetonitrile containing 0.1 % of formic acid at a flow rate of 0.4 mL/min. Ertapenem and its internal standard (ertapenem-D4) are detected by tandem mass spectrometry using positive electrospray ionization and multiple reaction monitoring, and using 476.2 → 346.0/432.2 as mass transition for ertapenem and 480.2 → 350.0 for its internal standard.

Results
No significant interferences or carry-over contamination were observed. Imprecisions, absolute relative bias, matrix effects and normalized recoveries were ≤14.5 %, ≤9.3 % (92.8–104.5) % and (98.8–105.8) %, respectively. Chromatographic measurement procedures were linear from (0.50–100) mg/L.

Conclusions
The measurement procedures based on UHPLC-MS/MS developed and validated in this study could be useful in pharmacokynetic and pharmacodynamic studies in subjects with liver cirrhosis who develop spontaneous bacterial peritonitis treated with ertapenem.
From BRICS to BRICS+: Sheer More Members is not a Challenge to G7
Authors: Kamin Katrin , Langhammer Rolf J. 
Published: December 2023

Abstract
The global economic landscape is undergoing a transformative shift, as evidenced by the BRICS nations’ increasing dominance. This development raises questions about the emergence of economic and political blocks and their potential leverage. China and India, as the world’s most populous nations within the group, are instrumental in driving global economic demand. The expansion of BRICS, with new members possessing vast natural resources, amplifies the group’s influence. However, the BRICS face a monetary and financial Achilles heel, especially in the case of China, hindering their ability to act independently. As the BRICS gain geopolitical significance, the G7 responds with infrastructure initiatives and trade agreements, though success hinges on reciprocal concessions. The BRICS thus serve as a wake-up call for the G7, prompting considerations of rejuvenating political and economic links amidst a shifting global landscape.
Temporal dynamics of green urban areas in Romania. A comparison between spatial and statistical data
Authors: Albulescu Andra-Cosmina , Larion Daniela 
Published: December 2023

Abstract
The social function and the ecosystem services provided by green urban areas (GUAs) have long been acknowledged by both the scientific community and the public. They become even more relevant to urban sustainability and human welfare in the post-pandemic world, which still has to confront social, environmental, and energy-related issues. This study aims to provide an example of how to perform a temporal dynamics-focused analysis of GUAs in an unsatisfactory data context by comparing the results obtained via spatial and statistical datasets of 35 cities in Romania considering the 2006–2018 period as a reference. This integration represents a compromise solution that should offer insights into the GUA’s dynamics in difficult monitoring conditions determined by the absence of both high-resolution spatial datasets and metadata-enhanced statistical datasets. Specific patterns of the GUA’s dynamics are identified, and the differences between the spatial data and statistical data-based findings are discussed. For at least 78% of the analysed cities, the official statistical data show that the GUAs are larger than the ones computed via GIS, in all reference periods. The findings call for the improvement of the GUA quantification and mapping regulations and programmes, which target, among other elements, their transparency and validation.
Selenium prevented renal tissue damage in lipopolysaccharide-treated rats
Authors: Hedayati-Moghadam Mahdiyeh , Seyedi Fatemeh , Hosseini Mahmoud , Mansouri Mostafa , Sotoudeh Mohammad Mahdi , Beheshti Farimah , Askarpour Hedyeh , Kheirkhah Aliasghar , Baghcheghi Yousef 
Published: December 2023

Abstract

Objectives
Kidney diseases are one of the common diseases, which are one of the main causes of death in society and impose costs on the health system of the society. A growing body of evidence has well documented that inflammatory responses and oxidative damage play a significant role in the progress of various kidney diseases.

Methods
This study examined whether selenium (Sel) could prevent the detrimental influences of lipopolysaccharide (LPS) in rats. Four groups of Wistar rats were considered: control, LPS (1 mg/kg, i.p., for 14 days), LPS–Sel 1 (0.1 mg/kg, i.p., for 14 days), and LPS–Sel 2 (0.2 mg/kg, i.p., for 14 days).

Results
Sel treatment markedly attenuated oxidative stress damage in the kidney tissue in LPS-induced renal toxicity. Generally, the administration of Sel resulted in improved antioxidant indicators such as catalase (CAT) and superoxide dismutase (SOD) activities, or total thiol content, and decreased malondialdehyde (MDA) in the kidney tissue. It also decreased interleukin-6 in kidney homogenates. Furthermore, Se treatment significantly inhibited the elevation of serum biochemical markers of kidney function including serum, BUN, and creatinine.

Conclusions
Based on the findings of the current study, it seems that the administration of Sel to LPS-treated rats improves renal function by reducing oxidative damage and inflammation in kidney tissue. However, more research is needed to reveal the accurate mechanisms for the effect of Sel on renal outcomes of LPS in human subjects.
Integrating interview-based approaches into corpus-based translation studies and literary translation studies
Authors: Vîlceanu Titela 
Published: December 2023

Abstract
The article discusses the increasing role of corpus data in translation studies (a field that has developed several autonomous sub-fields striving for full recognition), including mediated interviews of literary translators as paratexts complementing textual analysis in the translated text circulation, appreciation, and evaluation. The question of corpus design should be envisaged in conjunction with corpus usability, i.e. fitness for purpose. In this respect, it is important to train awareness of the potential of corpora of mediated interviews in real-life settings, in literary translation research and work environments. Furthermore, the article is intended to contribute to building more productive and innovative interfaces of corpus-based translation studies and literary translation studies in the digital humanities era, as well as to provide tools meant to bridge the gap between theory and practice.
The HfFe2Si2 type silicides ScT
2Si2 (T = Ru, Rh, Os) – structure and solid-state 29Si/45Sc NMR spectroscopy
Authors: Koldemir Aylin , Gerdes Josef Maximilian , Reimann Maximilian Kai , Hansen Michael Ryan , Pöttgen Rainer 
Published: December 2023

Abstract
The silicides ScT
2Si2 (T = Ru, Rh, Os) were synthesized by arc-melting of the elements and subsequent annealing in sealed silica ampoules. They crystallize with the rarely observed HfFe2Si2 type structure, space group Pbcm. The structures of ScRu2Si2 (a = 761.64(4), b = 730.70(6), c = 521.07(6) pm, wR = 0.0314, 633 F
2 values, 31 variables) and ScOs2Si2 (a = 771.10(8), b = 736.68(7), c = 521.88(5) pm, wR = 0.0479, 623 F
2 values, 31 variables) were refined from single crystal X-ray diffractometer data. The refinements showed small degrees of Ru/Si respectively Os/Si mixing on one 4c site, leading to the refined compositions ScRu1.96(1)Si2.04(1) and ScOs1.91(1)Si2.09(1). The monomeric building units in both structures are two slightly distorted, crystallographically independent RuSi5 respectively OsSi5 square pyramids, which are condensed via common edges. The resulting densely packed [Ru2Si2] and [Os2Si2] networks leave voids for the scandium atoms with coordination number 18: Sc@Si8Ru8Sc2 and Sc@Si8Os8Sc2. Temperature dependent magnetic susceptibility measurements of ScRu2Si2 and ScOs2Si2 indicate Pauli paramagnetism. Solid-state 29Si and 45Sc static and MAS NMR spectroscopy reveal significant Knight shifts and a strong influence of the T/Si mixing on the experimental NMR line shapes. A larger overall 29Si magnetic shift for ScRu2Si2 compared to ScOs2Si2, although with a negative sign for one of the 29Si resonances, suggests stronger paramagnetic effects for ScRu2Si2, in agreement with the magnetic susceptibility measurements.
Hobbes y la libertad política como no-arbitrariedad
Authors: Bello Hutt Donald 
Published: December 2023

Hobbes defendió un concepto de libertad política como no-arbitrariedad. Esta hipótesis rechaza una interpretación dominante que considera que el inglés defiende un concepto de libertad política como mera ausencia de interferencias. El artículo contribuye a clarificar el potencial de la teoría de Hobbes en lo referente al rol que el Estado juega en la tarea de asegurar que los ciudadanos puedan vivir no sólo vidas no interferidas, sino no sujetas a cambios arbitrarios. Contribuye también a precisar los contornos de las diferencias entre la tradición liberal y la republicana.
The Short Dramatic Form in the Works of Kostas Ostrauskas and Juozas Erlickas
Authors: Klišienė Neringa 
Published: December 2023

Short dramatic forms have become theatrical objects that are not easily identifiable. They act as a symbol of questioning the foundations of the conventional drama and a reflection on the dramatic genre in general. The article focuses on its ambiguous treatment and its actualisation in the context of contemporary Lithuanian dramaturgy. Micro-drama, miniature, one-shot drama, or ‘dramatized’ proverbs and sayings – these are the playwrights’ own denominations indicating a kind of tendency which emerged at the end of the 20th century, or, at least, the search for an original term or word. At the same time, however, this effort also signals the inscription of short-format dramatic texts into a certain mediatic area of literature and theatre, which is primarily seen as a sign of a certain bargain with the reader. The article does not look at short-form texts so much through the prism of theatrical evolution, but rather focuses on the mechanism of short-form writing. The question is whether (and how) such ‘mutations’ of dramatic writing maintain a specific theatrical mode of operation (the plot, the character etc.) when they enter the dynamic field of the short form. It is concluded that its mechanism is related to maximum cost-effectiveness and economy of language, and, through the reduction of the aforementioned dramatic triad, the function of the perceiver and his/her interpretative work are radicalised.
Modelling of concepts "purpose", "goal", "task", and "function" in law
Authors: Čyras Vytautas 
Published: December 2023

The formalisation of concepts a ``purpose'', ` ` goal'', ` ` task'', and ``` ` function'' in law is examined. Conceptual graphs called `` ` goal-task graphs'' are proposed to model them. A goal is associated with a predicate, which characterises the goal. A node represents a state, in which the predicate is true. An edge represents the task. A task e = (u, v) represents a mean to implement the state v, which assumes u.
Normal and integrable parabolic metric (φ, ξ, η, g, λ)-structures on hypersurfaces of parabolic integrable (F , G)-manifolds
Authors: Baškienė Angelė 
Published: December 2023

Parabolic (φ, ξ, η, λ)-structures and parabolic metric (φ, ξ, η, g, λ)-structures on hypersurfaces of parabolic integrable F-manifolds and parabolic integrable (F, G)-manifolds, respectively, are regarded. Necessary and sufficient normality and integrability conditions of these structures have been found.
THE ENVIRONMENTAL PARAMETERS SUITABILITY FOR MULTISPECIES-BASED MARICULTURE IN PONGOK ISLAND WATERS, BANGKA BELITUNG
Authors: Adibrata Sudirman , Pamungkas Aditya , Priyambada Agung , Wahidin La Ode , Hidayat Syahrin Imron 
Published: December 2023

Pongok Island possesses small islands surrounded by waters with some primary commodities of sea farming. Seeking appropriate locations for marine aquaculture is a careful planning step to acquire optimal results. The sustainability of sea farming areas should be set based on considering species for easy implementation. This research aimed to analyse the area's suitability for aquaculture activities of seaweed cultivation, rearing groupers, and lobsters in floating net cages, and pearl oyster farming. This research occurred from June to November 2022 in Pongok Islands, South Bangka Regency, Indonesia. The method used in this research consisted of parameters weighting and scoring for cultivating seaweeds, groupers, or lobsters utilizing floating net cages and pearl oysters. Sea water samples analysis was processed in the Marine Science Laboratory of Bangka Belitung University and PT Global Quality Analytical, Bogor – West Java. Collected data were then scaled based on expert justification of scaling priority on aquaculture suitability. The mapping area of sea farming locations based on potential resources was then determined using map software. This research indicates that cultivating seaweeds is recommended to be established in two stations, 1 (149.79 ha) and 2 (186.46 ha), that are very suitable (S1) and the suitable (S2) categories, respectively. Station 3 (325.41 ha) and 4 (4.11 ha) are grouped into very suitable (S1) categories for pearl oysters and groupers or lobsters using floating net cages, respectively. The total estimate for sea farming in the waters of Pongok Island is 665.77 ha. Allocating seawater spaces should be assigned for sustainable fishery management. Maps of area suitability for sea farming can obviate conflicts in seawater areas.