bluuebunny/crossref_metadata_2025_split huggingface dataset:
The relationship between ASIC3 gene polymorphism and fibromyalgia syndrome
Authors: Zontul Cemile , Tas Ayca , Hayta Emrullah , Silig Yavuz 
Published: October 2023

Abstract

Objectives
Fibromyalgia syndrome (FMS) is a chronic pain syndrome characterized by widespread body pain over a long period, the cause of which is not yet clearly known. FMS patients usually have high pain sensitivity. We aimed to investigate whether rs4148855 and rs2288646 polymorphisms of acid-sensing ion channel 3 (ASIC3), one of the factors contributing to pain, cause a predisposition to FMS in the Turkish population.

Methods

ASIC3 gene rs4148855 and rs2288646 polymorphisms in DNA samples obtained from blood samples of 175 patients with FMS and 176 healthy individuals were analyzed by real-time polymerase chain reaction (RT-PCR) using a hydrolysis probe. Statistical data were obtained by chi-square (χ2) test and logistic regression analysis.

Results
No significant association was found between ASIC3 gene rs4148855 and rs2288646 polymorphisms and the Turkish population’s FMS group and control group (p>0.05).

Conclusions
As a result, no significant association was found between the genotype and allele distributions of ASIC3 polymorphism (rs4148855 and rs2288646) in patients with FMS compared to controls in the Turkish population. Further studies are needed to elucidate the relationship between ion channels and FMS to elucidate the mechanisms of FMS.
Green synthesis of copper nanoparticles using Citrullus colocynthis leaves extract: photocatalytic, antimicrobial and antioxidant studies
Authors: Nazir Arif , Alam Shakeel , Alwadai Norah , Abbas Mazhar , Bibi Ismat , Ali Abid , Ahmad Naveed , Al Huwayz Maryam , Iqbal Munawar 
Published: October 2023

Abstract
Considering the ecofriendly aspects of green synthesis, copper nanoparticles (Cu NPs) were produced using leaves extract of Citrullus colocynthis (Desert Gourd) as a reducing agent and CuSO4 as a Cu precursor. The characterization of synthesized Cu NPs was performed using various techniques including UV-Visible spectroscopy (UVS), Fourier Transform Infrared (FTIR), Scanning Electron Microscopy (SEM), X-ray diffraction (XRD) and Energy dispersive X-ray (EDX). The tested NPs (face centered cubic) were determined to possess an average size of 17 ± 4.2 nm with spherical shape which exhibited highest absorption (λ
max) at 560 nm. These NPs were assessed for their potential to function as a photocatalyst in degradation of methylene blue (MB) dye under UV light and a significant degradation (65 %) of MB dye was observed within irradiation period of 160 min. The Cu NPs displayed a promising antibacterial activity (ABA) against various bacterial cultures such as P. multocida, Botryococcus subtilis, S. aureus and Escherichia coli. While, appreciable antioxidant potential (AP) of tested nanoparticles was also revealed by various invitro antioxidant assays including total phenolic contents (TPC), total flavonoids contents (TFC) and diphenyl picrylhydrazyl (DPPH) assays. The fabrication of Cu NPs through green route, the use of C. colocynthis extract is recommended as an effective antimicrobial, antioxidant and photocatalytic agent as green route offers various advantages over chemical synthesis.
Infrared Drying for Water Content Measurements of Soils
Authors: Arsoy Sami 
Published: October 2023

Abstract
The water content of soils is frequently needed, and its reference value is currently obtained by conventional convection ovens. Infrared (IR) ovens appear to be overlooked by the geotechnical community even though they allow for precise control over temperature, much faster heat transfer, and much better energy efficiency resulting from its inherent low thermal inertia. The European Commission’s climate action enacts several policies for greener, sustainable, and energy efficient solutions. The objective of this study is to investigate the usability and efficiency of IR ovens as the permanent replacement for conventional ovens for supporting a greener and sustainable environment. Particular emphasis is given to precision and energy efficiency through experimental comparisons. The results suggest that IR ovens offer 70 % implied energy savings over conventional ovens while resulting in comparable precision. It is, therefore, proposed to adopt IR ovens as the new and preferred standard for water content determination and to abandon conventional ovens after a transition period.
Experimental Study and Mechanism Analysis on Compression–Shear Behavior of Hydraulic Asphalt Concrete at Different Temperatures
Authors: Yu Zhenpeng , Yang Qi , Tang Rui , Li Furong 
Published: October 2023

Abstract
Hydraulic asphalt concrete (HAC), typically employed as an impermeable structure in embankment dams, is increasingly recognized for its widespread engineering applications. However, investigations of the mechanical performance of HAC under combined compressive–shear stress remain limited, particularly given its temperature sensitivity. Therefore, this study investigates the mechanical behaviors of HAC under combined compressive–shear stress at diverse temperatures and normal compressive stresses. Specifically, the failure modes, stress–strain curves, peak shear stress, and strain of HAC under various temperatures and normal compressive stresses are obtained for analysis. Experimental results demonstrate that the combination of normal compressive stress and temperature induces changes in peak shear stress and correlated shear strain. Increased normal compressive stress results in vertical restriction and the emergence of horizontal cracks, with deformation amplifying at elevated temperatures. All failure modes of HAC under these conditions are absent of spalled fines and debris. It is observed that as the normal compressive stress increases, the peak shear stress progressively increases, whereas an increase in temperature yields a clear decrease in peak shear stress. The shear strength of HAC comprises the cohesion strength of the asphalt matrix and the interfacial adhesion strength between aggregates and asphalt. Finally, three modified compressive–shear failure criteria that exhibit good prediction accuracy are established for HAC at diverse temperatures. This research offers a theoretical reference for the future investigation and engineering application of HAC.
Niobium Boronizing: Influence of the Treatment Temperature and Time
Authors: Ferreira Lauro Mariano , Cardoso Rodrigo Perito , D’Oliveira Ana Sofia C. M. 
Published: October 2023

Abstract
The application of niobium borides to components such as lamination cylinders, hightemperature devices, and medical equipment shows their importance and versatility in engineering. To improve niobium’s mechanical resistance and possible oxidation resistance at temperature, this research applied boronizing to pure niobium, carried out with double pack cementation. Boronizing at 950°C and 1,100°C was carried out for 1 and 4 h. Ekabor commercial pack mixture with a nominal chemical composition of 90 % silicon carbide, 5 % boron carbide, and 5 % potassium tetrafluoroborate was used with and without 10 percent by weight (wt%) silicon addition. Scanning electron microscope, energy dispersive spectroscopy, and X-ray diffraction analyses and microhardness tests were used to characterize the treated samples. A continuous high-hardness 2,394-HV0.1 (23.5 GPa) niobium diboride layer was formed at the surface of the niobium substrate. A maximum layer thickness of 53.6 ± 2.9 µm was measured after 4 h at 1,100°C, whereas after 1 h at 950°C, no visible layer was identified with the applied characterization techniques, suggesting a threshold in this temperature. Adding 10 wt% silicon to the pack mixture impacted the kinetics of the diffusion process, which resulted in an increase in layer thickness of 72.6 ± 10.1 µm after processing for 1 h at 1,100°C, but cracks formed in the processed surface.
Hyperthyroidism incidence in a large population-based study in northeastern Italy
Authors: Censi Simona , Salmaso Laura , Ceccato Filippo , Manso Jacopo , Fedeli Ugo , Saia Mario , Mian Caterina 
Published: October 2023

Objective
An improvement in iodine status in Veneto Region has been documented in the last decade. We aimed at estimating the incidence of hyperthyroidism in the Veneto Region (Italy) over the period 2013–2022.

Methods
Retrospective population-based study conducted in Veneto (4.9 million people) using the population registry, an administrative health database. Between 2012 and 2022, hyperthyroidism incidence was defined thank to a health-care co-payment exemption for hyperthyroidism or any hospital diagnosis of hyperthyroidism. Incident hyperthyroidism was defined from 2013 to 2022 to exclude prevalent cases. Standardized incidence rates (IRs) were reported by age, sex, and etiology of thyroid hyperfunction too.

Results
We identified 26,602 incident cases (IR of 54.38 per 100,000 person-years, 2.47-fold higher in females than in males). IR decreased from 69.87 (95% CI: 67.49, 72.25) in 2013 to 42.83 (95% CI: 40.99, 44.66) in 2022. In 2020, an out-of-trend decrease in hyperthyroidism incidence was documented, corresponding to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic outbreak, with a realignment to the trend in the subsequent years. The annual percentage change according to the cause of hyperthyroidism was as follows: −6.62% (95% CI: 8.47, 4.73) (P < 0.0001) in toxic multinodular goiter, −7.56% in toxic uninodular goiter (95% CI: 10.54, 4.48) (P < 0.001) and −4.70% (95% CI: 6.33, 3.04) in toxic diffuse goiter (Graves’ disease) (P < 0.001).

Conclusions
We documented a decline in the incidence of hyperthyroidism in Veneto Region, paralleling the improvement of the iodine status, thanks to a long and sustained iodine prophylaxis campaign. SARS-CoV-2 pandemic and vaccination campaign did not change the declining trend of hyperthyroidism incidence in our study region.

Significance statement
An improvement in iodine status in the population residing in the Veneto region has been documented in the last decade, thanks to a nationwide voluntary iodine prophylaxis program running since 2005, but its impact on the epidemiology of thyroid disease has never been documented. This is the largest study on the incidence rates of hyperthyroidism carried out in Italy and covers the longest observation period among all regionwide population-based studies of hyperthyroidism in our country. We documented a reduction in the incidence of hyperthyroidism, which was more pronounced in nodular goiter diagnosis but involved also toxic diffuse goiter. The decline in the incidence of hyperthyroidism in Veneto Region shows the efficacy and safety of the iodine prophylaxis campaign.
Macro-Aspartate Aminotransferase and Its Laboratory Detection: A Case Report
Authors: Aleknavičiūtė-Valienė Goda , Černiauskas Linas , Riauka Mantas , Vitkus Dalius 
Published: October 2023

Background. Increased enzyme activity in human blood serum is usually associated with the existence of disease. On the other hand, enzyme activity can also be elevated in the presence of benign conditions, such as macro-enzymes. Macro-enzymes could lead to highly unnecessary and invasive procedures which may cause complications to the patient and an extra cost for the hospital. Therefore, it is important to diagnose this condition in order to avoid unnecessary clinical tests.Case Presentation. We present a case of a 71-year-old asymptomatic female with persistent elevation of AST who was referred to our hospital for additional testing for underlying liver disease. By using polyethylene glycol (PEG) precipitation assay, we were able to identify macro-AST. This helped to avoid the high-risk liver biopsy procedure.Conclusion. In the case of an isolated elevation of AST activity with no clinical indications of liver disease, diagnostic work-up for macro-AST should always be considered by physicians.
The vicious cycle of family dysfunction and problematic gaming and the mediating role of self-concept clarity among early adolescents: A within-person analysis using random intercept cross-lagged panel modeling
Authors: Zhou Jianhua , Zhao Haiyan , Wang Li'an , Zhu Dandan 
Published: October 2023

AbstractBackgrounds and aimsFamily dysfunction is a significant risk factor for adolescent problematic gaming, yet few studies have investigated the bidirectional relations between changes in family dysfunction and adolescent problematic gaming and potential mediating mechanisms. This study thus examined the bidirectional relations between family dysfunction and adolescent problematic gaming and the mediating role of self-concept clarity within this relation.MethodsParticipants included 4,731 Chinese early adolescents (44.9% girls; M age = 10.91 years, SD = 0.72) who were surveyed at four time points 6 months apart.ResultsRandom intercept cross-lagged panel modeling found (a) family dysfunction directly predicts increased problematic gaming, (b) adolescent problematic gaming directly predicts increased experience of family dysfunction, (c) family dysfunction indirectly predicts problematic gaming via self-concept clarity, and (d) adolescent problematic gaming indirectly predicts family dysfunction via self-concept clarity.Discussion and conclusionsThe present study suggests that adolescents may be trapped in a vicious cycle between family dysfunction and problematic gaming either directly or indirectly through impairing their self-concept clarity. Findings indicate fostering youth self-concept clarity is essential to break the vicious circle between dysfunctional experiences in the family and problematic gaming among adolescents.
Content Analysis of Locally Marketed Energy Drinks: Turkish Market
Authors: PEKER Zafer , KÖSE Dursun Ali 
Published: October 2023

In the Turkish Food Codex Communique on Energy Drinks, energy drinks are defined as "flavored non-alcoholic beverage containing caffeine, containing taurine, glucuronolactone, inositol, carbohydrates, amino acids, vitamins, minerals, and other food and components". The amount of caffeine in the composition of the energy drink cannot be more than 150 mg/L, inositol 100 mg/L, glucuronolactone 20 mg/L, and taurine 800 mg/L. It has been reported that the consumption of beverages containing caffeine, taurine, and glucuronolactone in healthy young adults increases arterial blood pressure and platelet aggregation and decreases endothelial function. For healthy adults, consuming more than 400 mg of caffeine daily and consuming more than 500 ml of energy drinks in energy drinks, as well as consuming energy drinks with or together with alcohol, is risky and not recommended. Energy drinks are risky for children, people under the age of 18, the elderly, diabetics, those with high blood pressure, pregnant and lactating women, those with metabolic diseases, kidney failure, and people who are sensitive to caffeine. The use of energy drinks has been increasing rapidly in the world and in our country in recent years. Usually, energy drinks are used by young people, athletes, and people who live actively. Energy drinks are also preferred as a pleasure or to increase mental, physical, and cognitive performance.
The aim of our study is to analyze the components of the content and the effectiveness of the components by making a qualitative analysis with the GC-MS (Gas Chromatography-Mass Analysis) device of many energy drinks used in the market. In addition, it is the evaluation of the energy drinks available in the market by examining the effects of the determined substances and their amounts on human health.
DESVENDANDO AS RELAÇÕES ENTRE NEOLIBERALISMO, RACISMO E COLONIALIDADES
Authors: Pereira Alves Nogueira Valdenete 
Published: October 2023

Este artigo tem como objetivo construir um referencial teórico que explore a relação entre o neoliberalismo, racismo e as colinialidades, destacando a correlação entre ambos. Para isso, serão utilizados os conceitos e perspectivas de renomados autores, como Jessé Souza, Grada Kilomba, Silvio Almeida, Quijano, David Harvey, Walter Mignolo, Catherine Walsh e outros. Através dessa análise, evidencia-se como o neoliberalismo e o racismo se interconectam, fornecendo uma base teórica sólida para compreender as dinâmicas sociais e políticas atuais; e a promoção da conscientização e a mobilização social, enfatizando a necessidade de uma luta coletiva em busca do fim das colonialidades e da construção de uma sociedade mais justa e equitativa. As relações entre neoliberalismo, racismo e colonialidades são complexas e estão interligadas de várias maneiras. Uma das formas como o neoliberalismo está relacionado ao racismo é por meio das desigualdades sociais e econômicas que são agravadas pelas políticas neoliberais; as desigualdades econômicas muitas vezes estão correlacionadas com divisões raciais e étnicas.
A Characterization of Lie Type Higher Derivations on von Neumann Algebras with Local Actions
Authors: Kawa Ab Hamid , Alsuraiheed Turki , Hasan S. N. , Ali Shakir , Wani Bilal Ahmad 
Published: October 2023

Let $m$ and $n$ be the fixed positive integers. Suppose $\mathcal{A}$ is a von Neuman algebra with no central summands of type $I_{1}$ and $L_{m}$ be a Lie type higher derivation i.e., an additive (linear) map $L_{m} :\mathcal{A}\to \mathcal{A}$ such that
\begin{equation}\label{def2}
\[L_{m}(p_{n}(\mathfrak{S}_{1},\mathfrak{S}_{2},\cdots,\mathfrak{S}_{n}))=\sum_{l_1+l_2+\cdots+l_n=m}p_{n}\big(L_{l_1}(\mathfrak{S}_{1}),L_{l_2}(\mathfrak{S}_{2}),\cdots,L_{l_n}(\mathfrak{S}_{n})\big)\]	%L_{m}(p_{n}(\mathfrak{S}_{1},\mathfrak{S}_{2},\cdots,\mathfrak{S}_{n}))=\sum_{l_1+l_2+\cdots+l_n=m}p_{n}\big(L_{l_1}(\mathfrak{S}_{1}),L_{l_2}(\mathfrak{S}_{2}),\cdots,L_{l_n}(\mathfrak{S}_{n})\big)\nonumber
\end{equation}
for all $\mathfrak{S}_{1},\mathfrak{S}_{2},\cdots,\mathfrak{S}_{n}\in \mathcal{A}$. In the present paper, we study Lie type higher derivations on von Neuman algebras and prove that every additive Lie type higher derivation on $\mathcal{A}$ has a standard form at zero product as well as at projection product. Further, we discuss some more related results.
Teaching Competencies and Classroom Performance of University Teachers: Soft Skills as a Mediator
Authors: Saleem Amna , Akhtar Dr. Zarina 
Published: October 2023

Soft skills are personal qualities that enable teachers to better engage with students. The purpose of the current study was to examine the role of soft skills as a mediator in the relationship between teaching competencies and classroom performance among university teachers. This study was quantitative and followed the positivist research paradigm. The researchers selected the study sample using multistage sampling. Two questionnaires and an observation sheet were used in this study. Researchers collected data from 132 public-sector university teachers in southern Punjab. SPSS and PROCESS macro were used to analyze the data. The data was analyzed using mediation analysis. The major conclusion of this study was that all the variables (teaching competencies, soft skills, and classroom performance) had a significant relationship, and soft skills also mediated between teaching competencies and classroom performance of university teachers. The major recommendation of the study is that future researchers include variables that may influence the performance of teachers in the classroom, such as job satisfaction, work discipline, motivation, and so forth, and also change the indicators for teaching competencies and soft skills.
Espacios cardioprotegidos en México: acciones para prevenir la muerte súbita cardiaca. Una postura de profesionales de la salud
Authors: Martínez-Duncker R David , Urzúa-González Agustín Ramiro , Aguilera-Mora Luisa Fernanda , Laínez-Zelaya José S , Álvarez de la Cadena-Sillas Jorge , Celaya-Cota Manuel de Jesús , González-Cruz Erik H , Delgado Elisa , Campos-Nonato Ismael , Denova-Gutiérrez Edgar , Cruz-Valdez Aurelio , Cossio-Aranda Jorge Eduardo , Guerra-López Arturo , Enciso-Muñoz José Manuel , Sánchez-Arreola Luis Daniel , Magaña-Serrano José Antonio , Díaz-Aguilera Miguel Ángel , Gómez-Álvarez Enrique , Oseguera-Moguel Jorge , Barquera Simón , Sifuentes-Osornio José , Lazcano Ponce Eduardo C 
Published: October 2023

La muerte súbita cardiaca es un problema de salud pública a nivel mundial. Aunque su incidencia no es conocida, se estima que causa hasta 50% de la mortalidad de origen cardíaco y hasta 20% de la mortalidad total en los adultos. En México, estimaciones previas sugieren que causa en promedio 33 000 muertes al año; sin embargo, los datos no son precisos. La mitad de los eventos por muerte súbita cardiaca se deben a un paro cardiaco súbito extrahospitalario que, de no ser atendido oportunamente, deriva en una muerte súbita cardiaca. Por tanto, la capacidad de responder pronta y adecuadamente a estos eventos con las maniobras y equipos necesarios mejora la sobrevida de las víctimas. Para atender este problema, en algunos estados del país se han creado espacios cardioprotegidos que permiten realizar maniobras de reanimación cardiopulmonar y desfibrilación cardiaca de acceso público oportunamente. Como objetivo, los profesionales de la salud establecen la importancia de implementar espacios cardioprotegidos y crear políticas públicas al respecto en todo el país.
A Sequential Feature-Based Rate of Penetration Representation Prediction Method by Attention Long Short-Term Memory Network
Authors: Cheng Zhong , Zhang Fuqiang , Zhang Liang , Yang Shuopeng , Wu Jia , Li Tiantai , Liu Ye 
Published: October 2023

Summary
In the petroleum and gas industry, optimizing cost-effectiveness remains a paramount objective. One of the key challenges is enhancing predictive models for the rate of penetration (ROP), which are intricately tied to the delicate interplay between significant parameters and drilling efficiency. Recent research has hinted at the potential of temporal and sequential elements in drilling, but a detailed exploration and understanding of these dynamics remain underdeveloped.
Addressing this research gap, our primary innovation is not just the introduction of a model but rather the employment of the attention-based long short-term memory (LSTM) network as a tool to deeply analyze the role of sequential features in ROP prediction. Beyond merely applying the model, we furnish a robust foundation for sequential analysis, detailing data processing methods and laying out comprehensive data analytics guidelines for such temporal assessments. The utilization of the LSTM network, in this context, ensures meticulous capture of real-time drilling data nuances, providing insights that are both profound and actionable.
Through empirical evaluations with real-world data sets, we accentuate the vital importance of time-sequential dynamics in refining ROP predictions. Our methodological approach, tailored for the oilfield domain, is both rigorous and illuminating, achieving an R2 score of 0.95 and maintaining a relative error under 10%. This effort goes beyond simply proposing a new predictive mechanism. It establishes the centrality of sequential analysis in the drilling process, charting a course for future research and operational optimization in the petroleum and gas sector. We not only offer enhanced modeling strategies but also pioneer insights that can shape the next frontier of industry advancements.