bluuebunny/crossref_metadata_2025_split huggingface dataset:
Factors associated with millennial nurses’ intention to pursue formal leadership roles: a cross-sectional study
Authors: Labrague Leodoro J. , Al Sabei Sulaiman , Al Rawajfah Omar , Burney Ikram Ali , Abu AlRub Raeda 
Published: October 2023

Purpose
This study aims to examine the level of intention to pursue formal nursing leadership roles among millennial nurses and to identify the different factors that may play a role in their intentions to pursue such roles.

Design/methodology/approach
This study used a multi-center, cross-sectional research design. Registered nurses born between 1980 and 2000 (n = 1,377) who worked in 23 acute care hospitals in Oman were included in this study. Data were analyzed using descriptive statistics and multiple linear regression. Data were collected between July 2019 and January 2020.

Findings
Nearly 70% of millennial nurses researched their intention for career advancement to assume nursing leadership responsibility. Factors associated with nurses’ intention to pursue formal nursing leadership roles were the type of nursing degree held (having a bachelor of science in nursing degree), type of hospital facility affiliation (teaching hospital), previous leadership experience, structural empowerment (access to support, opportunity and resources), work satisfaction and job burnout.

Originality/value
Millennial nurses, who represent the largest segment of the nursing workforce, have begun assuming nursing management and leadership roles; however, little is known about the factors affecting their intentions to pursue these roles. The findings of this study revealed different factors (both modifiable and nonmodifiable) influencing millennial nurses’ intentions to pursue formal leadership roles.
Trauma-informed librarianship: an exploratory literature review of trauma-informed approaches in school, academic and public libraries
Authors: Founds Stephanie D. 
Published: October 2023

PurposeThe goal of this review is to conduct an exploratory literature review on trauma-informed approaches in libraries to understand how librarians are discussing trauma-informed approaches and their integration into professional practice.Design/methodology/approachThe author reviewed materials indexed in selected EBSCOHost databases. Included materials from selected EBSCOHost databases were available to the author in full text, in the English language and about trauma-informed approaches in libraries. Items were excluded from this review if they were a review of another work, a thesis or dissertation, or letters to or from the editor.FindingsTwenty-five publications were included in this analysis. Publications included described approaches in school libraries, academic libraries and public libraries. Key topics are racial trauma-informed practices, trauma-informed teaching, resisting re-traumatization, social work and the effects of workplace trauma on the library workforce.Practical implicationsTrauma-informed approaches are gaining popularity in a variety of disciplines as the world copes with the turbulent events of recent years. The practical implications of this review are to explore the emergence of trauma-informed approaches in libraries to understand the current publishing landscape on this topic.Originality/valueWhile librarians are writing about this approach and some are incorporating it into their practice, an analysis in the form of an exploratory literature review to summarize this work has not been done. Understanding how libraries are incorporating this trauma-awareness and trauma-informed principles into the work is crucial for identifying the future approach to library services.
Investigating the emerging and future trends of knowledge management in small and medium enterprises: a science mapping approach
Authors: Fauzi Muhammad Ashraf , Saad Zuria Akmal , Ahmad Mohd Hanafiah , Fauzi Muhammad Zorif , Ahmad Md Faizal 
Published: October 2023

Purpose
This study aims to evaluate the knowledge structure of knowledge management (KM) applications within small and medium enterprises (SMEs). In pursuit of excellence, SMEs must adopt KM like large corporations, even with limited resources.

Design/methodology/approach
Through a bibliometric approach, this study evaluates current themes based on bibliographic coupling analysis and predicts future trends based on coword analysis. A total of 726 documents and 2,658 keywords were derived from the Web of Science database.

Findings
Findings show four clusters in bibliographic coupling and three in coword analysis. A common theme discovered converged on digital technology to ensure SMEs follow current market trends.

Research limitations/implications
Advanced application of Industry 4.0 requires digital transformation for SMEs’ pursuit of excellence. Implications include sustaining SMEs through a considerable KM system integrated with digital technology for sustainable business activities.

Originality/value
To the best of the authors’ knowledge, this study is among the first to provide a science mapping analysis on KM in SMEs by applying a bibliometric analysis.
Enhancing apathy treatment in Jordanian people living with dementia residing in care homes using virtual reality reminiscence therapy
Authors: Abdalrahim Asem , Suliman Mohammad , ALBashtawy Mohammed , Alkhawaldeh Abdullah , Ta'an Wafa'a 
Published: October 2023

Purpose
This paper aims to explore examine the therapeutic potential of head-mounted display (HMD)-based Virtual Reality Relaxation Therapy (VRRT) sessions for people individuals with dementia in Jordan.

Design/methodology/approach
This cross-sectional survey recruited 75 dementia-diagnosed elderly individuals from three Jordanian care homes. A VRRT intervention comprising 10 tailored RT sessions held over the course of five weeks was administered to the participants. Apathy, cognitive performance, anxiety and depression were evaluated before and after the intervention to determine any changes. The Person-Environment Apathy Rating Scale's (PEARS) Arabic translation's validity and reliability were also evaluated.

Findings
The VRRT intervention yielded noteworthy results in reducing apathy, as indicated by a substantial decrease in PEARS scores from 17.20 to 11.15. The findings of the study revealed that the participants demonstrated enhanced cognitive abilities, as evidenced by a significant rise in their Saint Louis University Mental Status ratings, which increased from 15.11 to 19.70. The levels of anxiety and depression exhibited a significant decrease subsequent to the implementation of VRRT, with anxiety levels decreasing from 13.66 to 8.23 and depression levels decreasing from 13.62 to 9.33. Furthermore, a notable 70% of participants demonstrated statistically significant decreases in indifference.

Practical implications
This study makes a significant contribution to the advancement of innovative treatment approaches aimed at addressing the needs of the aging population, hence enhancing health outcomes and raising the quality of care in Jordan.

Originality/value
The effectiveness of VRRT in reducing apathy among Jordanian senior citizens residing in nursing homes has not yet been fully investigated. Therefore, this paper seeks to assess the effectiveness of HMD-based VRRT by conducting pre- and post-intervention evaluations. This research aims to provide valuable insights into the applicability and significance of VRRT in the Jordanian context, contributing to the development of culturally appropriate and cutting-edge therapeutic interventions for older individuals in Jordan. Through this study, the authors aim to promote improved health and elevated standards of care for this population.
Effectiveness of occupational therapy interventions on function and occupational performance among adults with conditions of the hand, wrist, and forearm: A systematic review and meta‐analysis
Authors: Sheerin Margo , O'Riordan Cliona , Conneely Mairead , Carey Leonora , Ryan Damien , Galvin Rose , Morrissey Ann‐Marie 
Published: October 2023

AbstractIntroductionThis systematic review and meta‐analysis examines the effectiveness of occupational therapy interventions for adults with conservatively managed conditions of the hand, wrist, and forearm.MethodsSearches were carried out in CINAHL, Cochrane Central Register of Controlled Trials (CENTRAL), Cochrane Database of Systematic Reviews, MEDLINE (OVID), EMBASE, and PubMed. Grey literature was searched for via Google Scholar. A systematic literature search was undertaken for randomised studies that examined occupational therapy interventions for treatment of hand, wrist, and forearm conditions. The primary outcome was function, with secondary outcomes of occupational performance, satisfaction with occupational performance, pain, and quality of life. Meta‐analyses were completed, and GRADE was used to determine the certainty of evidence.ResultsTwelve studies with 1429 participants were identified. Interventions included combinations of occupation‐based intervention, assistive device provision, education, orthosis provision, and exercise programmes for arthritis, carpal tunnel syndrome, and fracture and tendon injuries of the hand, wrist, and forearm. Occupational therapy resulted in an improvement of function (REM, SMD −0.27, 95% CI −0.00 to −0.53, I2 = 69%, low certainty evidence) (p = 0.05), occupational performance (REM, SMD 0.83, 95% CI 1.61–0.06, I2 = 91%, low certainty evidence) (p = 0.04), satisfaction with occupational performance (REM, SMD 0.74, 95% CI 1.42–0.05, I2 = 89%, low certainty evidence) (p = 0.03), and pain reduction (FEM, MD −1.35, 95% CI −0.84 to −1.86, I2 = 0%, moderate certainty evidence) (p < 0.00001).ConclusionFurther high‐quality research is recommended to determine the effects of occupational therapy interventions on specific upper limb conditions, inclusive of a broader range of clinical and patient reported outcome measures.
Queer Ecologies and Anti-Colonial Abundance in Lionel Wendt's Ceylon
Authors: Coomasaru Edwin 
Published: October 2023

Abstract
Published posthumously in 1950, queer Sri Lankan photographer Lionel Wendt's photobook Ceylon crafted an aesthetic of queer environmental abundance. His photographs, ranging from documentary-style to surrealist-inspired images, were taken between 1933 and 1944, shaped by and contributing to rising waves of national consciousness and anti-colonial movements ahead of the island's independence in 1948. British rule since 1815 had destroyed common land and outlawed homosexuality for being ‘against the order of nature’. Wendt sought to confront and challenge colonial control over both ecology and sexuality, imagining alternative possibilities through both experimental and social realist photography. Other queer representations of the island (by Bevis Bawa, Ernst Haeckel and Edward Carpenter) are considered alongside the photographer's collaboration with queer, anti-imperialist filmmaker Basil Wright. Drawing on a queer ecological methodology and decolonial theory, this essay argues that Ceylon celebrated a queer environmental aesthetic of abundance by picturing Sri Lankan sexuality and landscapes as unbounded by colonial rule.
Decision‐making as discovery: Vetting clinical research in a leading precision oncology service
Authors: Cambrosio Alberto , Campbell Jonah , Drilon Alexander E. , Keating Peter , Polk Jess B. 
Published: October 2023

AbstractBased on fieldwork carried out at the Early Drug Development Service of a world‐leading cancer institution, our study sheds lights on decision‐making processes at the stage where decisions are made about which clinical trial to pursue and thus which experimental drugs will feed the growing pipeline of molecularly guided therapies and therapeutic strategies available to treating physicians. The paper shows how such collective decision‐making practices by a translational research unit employ formal tools and ad hoc valuation strategies that interweave technical‐scientific matters of concern with patient‐oriented clinical ones, as part of the institutional assetization of biomedical knowledge production. In the process, decision‐making practices in part define the conditions of possibility for the provision of care in what is increasingly becoming a ‘clinic of variants.’ They do so by reconfiguring on an evolving basis the socio‐material ecosystem through which precision oncology is enacted as a rapidly evolving assemblage of patients, physicians, research and support staff, protocols, molecular markers, drugs and administrative components.
Weathering the storm: A case study of organizational culture and effectiveness in times of disruptive jolts and crisis
Authors: Mokhtarifar Rasool , Zandi Farzad , Nazarian Alireza 
Published: October 2023

AbstractA crisis stems from an unexpected negative change in the environment, threatening the high‐priority values of the organization. As a crisis, the COVID‐19 pandemic jolted businesses worldwide, necessitating an investigation into the aspects of such an unsolicited change in the culture and effectiveness of organizations. With this aim, this research is based on a two‐step explanatory case study of a manufacturing firm. In the first step, to measure the change in the OC, a paired‐sample test was conducted using the Denison organizational culture survey model. Next, a qualitative inquiry was carried out, and the data were analysed through theme analysis. The results show significant changes in all 4 traits, including strategic direction and intent, vision and agreement, explained by the 12 qualitative themes. Ultimately, this study answers the long‐overlooked impact of a jolt, inducing a crisis, on the organizational culture. It sheds light on the importance of clarity of vision, core values and trust during a crisis.
Financing UK democracy: a stocktake of 20 years of political donations disclosure
Authors: Draca Mirko , Green Colin , Homroy Swarnodeep 
Published: October 2023

AbstractPolitical donations in the UK have been subject to comprehensive disclosure since 2001. We study the data produced as part of this disclosure policy to evaluate the role of private and public political finance over time. Total political donations have grown by nearly 250 per cent since 2001, reaching over £100 million in real terms for the first time in 2019. This increase has been driven by donations from private individuals, who now account for approximately 60 per cent of donations in election years compared to 40–50 per cent up to the late 2010s. Furthermore, ‘super‐donors’ (those contributing more than £100,000) have been a prominent driver of the rise, increasing their own share from approximately 31 per cent in 2017 to 45 per cent in 2019. We also show that private donations to the Labour Party fell sharply in the final stages of Jeremy Corbyn's leadership. These trends have benefited the Conservative Party, leading to a historic donation gap between the two main parties emerging circa 2019. We calculate that this gap between parties now stands at approximately £27 million compared to a historic average of £8–£10 million. This gap remains even after considering publicly funded ‘Short’ money provided to the opposition, which aims to increase competitive balance in the UK's democratic system.
Identification of a coagulation‐related signature correlated with immune infiltration and their prognostic implications in lung adenocarcinoma
Authors: Yang Siqian , Chen Shiqi , Zhao Yue , Wu Tao , Wang Yuquan , Li Tingting , Fu Liwan , Ye Ting , Hu Yue‐Qing , Chen Haiquan 
Published: October 2023

AbstractBackgroundLung adenocarcinoma (LUAD) is a fatal form of lung cancer with a poor prognosis. Coagulation system had been confirmed closely related to tumor progression and the hypercoagulable state encouraged the immune infiltration and development of tumor cells, leading to a poor prognosis in cancer patients. However, the use of the coagulation‐related genes (CRGs) for prognosis in LUAD has yet to be determined. In this study, we constructed an immune‐related signature (CRRS) and identified a potential coagulation‐related biomarker (P2RX1).MethodsWe obtained a total of 209 CRGs based on two coagulation‐related KEGG pathways, then developed the CRRS signature by using the TCGA‐LUAD RNA‐seq data via the procedure of LASSO‐Cox regression, stepwise‐Cox regression, univariate and multivariate Cox regression. Grouped by the CRRS, Kaplan–Meier survival curves and receiver operating characteristic curves were drawn for the training and validation sets, respectively. In addition, single‐sample gene set enrichment analysis was exploited to explore immune infiltration level. Moreover, immunophenotypes and immunotherapy grouped by CRRS were further analyzed.ResultsWe developed an immune‐related signature (CRRS) composed of COL1A2, F2, PLAUR, C4BPA, and P2RX1 in LUAD. CRRS was an independent risk factor for overall survival and displayed stable and powerful performance. Additionally, CRRS possessed distinctly superior accuracy than traditional clinical variables and molecular features. Functional analysis indicated that the differentially high expressed genes in the low‐risk group significantly enriched in T cell and B cell receptor signaling pathways. The low‐risk group was sensitive to anti‐PD‐1/PD‐L1 immunotherapy and displayed abundant immune infiltration and immune checkpoint gene expression. Finally, we identified an independent prognostic gene P2RX1. Low expression of P2RX1 associated with poor overall survival and decreased immune infiltration.ConclusionsOur study revealed a significant correlation between CRRS and immune infiltration. CRRS could serve as a promising tool to improve the clinical outcomes for individual LUAD patients.
Reducing rate of total colectomies for ulcerative colitis but higher morbidity in the biologic era: an 18‐year linked data study from New South Wales Australia
Authors: Giddings Hugh L. , Ng Kheng‐Seong , Solomon Michael J. , Steffens Daniel , Van Buskirk Joe , Young Jane 
Published: October 2023

AbstractBackgroundThis study aims to investigate the trends in UC surgery in New South Wales (NSW) at a population level.MethodsA retrospective data linkage study of the NSW population was performed. Patients of any age with a diagnosis of UC who underwent a total abdominal colectomy (TAC) ± proctectomy between Jul‐2001 and Jun‐2019 were included. The age adjusted population rate was calculated using Australian Bureau of Statistics data. Multivariable linear regression modelled the trend of TAC rates, and assessed the effect of infliximab (listed on the Pharmaceutical Benefits Scheme for UC in Apr‐2014).ResultsA total of 1365 patients underwent a TAC ± proctectomy (mean age 47.0 years (±18.6), 59% Male). Controlling for differences between age groups, the annual rate of UC TACs decreased by 2.4% each year (95% CI 1.4%–3.4%) over the 18‐year period from 1.30/100000 (2002) to 0.84/100000 (2019). An additional incremental decrease in the rate of TACs was observed after 2014 (OR 0.83, 95% CI 0.69–1.00). There was no change in the proportion of TACs performed emergently over the study period (OR 1.02, 95% CI 0.998–1.04). The odds of experiencing any perioperative surgical complication (aOR 1.54, 95% CI 1.01–2.33, P = 0.043), and requiring ICU admission (aOR 1.85, 95% CI 1.24–2.76, P = 0.003) significantly increased in 2014–2019 compared to 2002–2007.ConclusionsThe rate of TACs for UC has declined over the past two decades. This rate decrease may have been further influenced by the introduction of biologics. Higher rates of complications and ICU admissions in the biologic era may indicate poorer patient physiological status at the time of surgery.
Prospective comparison of diagnostic tests for bile acid diarrhoea
Authors: Borup Christian , Vinter‐Jensen Lars , Jørgensen Søren Peter German , Wildt Signe , Graff Jesper , Gregersen Tine , Zaremba Anna , Andersen Trine Borup , Nøjgaard Camilla , Timm Hans Bording , Lamazière Antonin , Rainteau Dominique , Hansen Svend Høime , Rumessen Jüri Johannes , Munck Lars Kristian 
Published: October 2023

SummaryBackgroundBile acid diarrhoea is often missed because gold standard nuclear medicine tauroselcholic [75‐Se] acid (SeHCAT) testing has limited availability. Empirical treatment effect has unknown diagnostic performance, whereas plasma 7α‐hydroxy‐4‐cholesten‐3‐one (C4) is inexpensive but lacks sensitivity.AimsTo determine diagnostic characteristics of empirical treatment and explore improvements in diagnostics with potential better availability than SeHCAT.MethodsThis diagnostic accuracy study was part of a randomised, placebo‐controlled trial of colesevelam. Consecutive patients with chronic diarrhoea attending SeHCAT had blood and stool sampled. Key thresholds were C4 > 46 ng/mL and SeHCAT retention ≤10%. A questionnaire recorded patient‐reported empirical treatment effect. We analysed receiver operating characteristics and explored machine learning applied logistic regression and decision tree modelling with internal validation.ResultsNinety‐six (38%) of 251 patients had SeHCAT retention ≤10%. The effect of empirical treatment assessed with test results for bile acid studies blinded had 63% (95% confidence interval 44%–79%) sensitivity and 65% (47%–80%) specificity; C4 > 46 ng/mL had 47% (37%–57%) and 92% (87%–96%), respectively. A decision tree combining C4 ≥ 31 ng/mL with ≥1.1 daily watery stools (Bristol type 6 and 7) had 70% (51%–85%) sensitivity and 95% (83%–99%) specificity. The logistic regression model, including C4, the sum of measured stool bile acids and daily watery stools, had 77% (58%–90%) sensitivity and 93% (80%–98%) specificity.ConclusionsDiagnosis of bile acid diarrhoea using empirical treatment was inadequate. Exploration suggested considerable improvements in the sensitivity of C4‐based testing, offering potential widely available diagnostics. Further validation is warranted. ClinicalTrials.gov: NCT03876717.
Call to action: Harmonization of pharmacovigilance regulations for post‐marketing pregnancy and breastfeeding safety studies
Authors: Alexe Amalia , Eisele Osa , Fernandes Maria Fernanda Scantamburlo , Garg Anju , Kovacs Birgit , Wurst Keele , Balramsingh‐Harry Leesha , Abramova Nadezda , Zheteyeva Yenlik , Lewis David 
Published: October 2023

AbstractGlobally, more than 200 million women become pregnant each year, most of whom receive medications despite limited information on their safe use during pregnancy. The paucity of drug safety data on pregnant and breastfeeding women stems from the routine exclusion of this population from clinical trials due to scientific, ethical, regulatory and legal concerns. Consequently, at the time of initial drug approval, there may be scant safety data to inform the drug benefit‐risk balance to the mother, foetus or infant. Although momentum is growing to include this underrepresented population in clinical trials, most information on drug exposure outcomes comes from data collected in the postmarketing setting. Regulatory guidance and legislation on medication use in pregnancy and breastfeeding were reviewed globally by the TransCelerate IGR PV Pregnancy and Breastfeeding Team. The International Conference of Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) standards and Council for International Organizations of Medical Sciences guidelines served as benchmarks for national safety regulations and guidance. The landscape assessment identified a lack of harmonization of global regulations on research in pregnant and breastfeeding women and a lack of specific regulations on this topic in the majority of the territories included in the assessment. This article focuses on the ambiguities and lack of harmonization in global regulations on postmarketing pregnancy and breastfeeding safety studies. There is currently no ICH standard to guide these types of safety studies and, in most regions reviewed, there are no clear regulations or guidance on when and how to conduct them. While a challenging undertaking, greater clarity and harmonization would facilitate more timely completion of postmarketing pregnancy safety studies that would ultimately generate the critical data needed to optimize benefit‐risk decisions for women who may conceive, as well as pregnant and breastfeeding women.