bluuebunny/crossref_metadata_2025_split huggingface dataset:
Dynamics of ATPase activity and lipid peroxidation indicators in liver tissue in experimental peritonitis using the drug “Seroguard”
Authors: Chepurnykh E. E. , Bogorodskaya S. L. , Shurygina I. A. , Rodionova L. V. , Samoilova L. G. , Shurygin M. G. 
Published: January 2025

Background. Oxidative stress plays an important role in the development of peritonitis, which leads to a decrease in antioxidant level and an increase in oxidant production. Studying ATPase activity and lipid peroxidation when using new methods of treating experimental peritonitis is of interest for clinical practice.The aim. To study the dynamics of ATPase activity and lipid peroxidation indicators in liver tissue in experimental peritonitis when using Serogard.Methods. The study was conducted on male Wistar rats aged 6 months. All animals were subjected to experimental peritonitis using the method we developed. Animals in the control group (n = 20) were intraperitoneally injected with 3 ml of physiological solution one day after modeling peritonitis; animals in the experimental group (n = 19) were injected Serogard® (AO Pharmasintez, Russia). We determined the initial values of the indicators in healthy rats (n = 7). In animal liver tissue, total and mitochondrial ATPase activity was studied, as well as the content of malondialdehyde (MDA) and diene conjugates (DC).Results. It was found that the total and mitochondrial activity of ATPases was suppressed by the day 3 of experimental peritonitis. During 14 days of the experiment, ATPase activity did not reach normal levels in any of the groups. However, animals in the experimental group had dynamics of a more steady, significant increase in the total ATPase and the mitochondrial ATPase (ATP synthase) activity with a significantly higher level than in the control group. MDA and DC in the experimental group increased by days 7–14, which indicated the activity of free radical processes and was also an indicator of the dynamics of restoration of metabolic and energy processes.Conclusion. Using Serogard in experimental peritonitis contributed to a more effective restoration of total ATPase activity and mitochondrial ATPase (ATP synthase) and on days 7–14 of the study led to an increase in the level of free radical processes activity that accompany and indicate the process of aerobic energy restoration.
Standardizing postoperative pain control for decompression of pediatric Chiari type I malformation by limiting narcotic usage
Authors: Reynolds Rebecca A. , Jenson Amanda V. , Battick Kentlee , Hartnett-Wright Sara , Rodriguez Luis F. , Jallo George , Akbari S. Hassan A. , Smyth Matthew D. 
Published: January 2025

OBJECTIVE
The aim of this study was to assess the effectiveness of a postoperative multimodal pain control protocol on perioperative pain scores in children undergoing decompression for Chiari type I malformation (CM-I).

METHODS
This retrospective matched cohort study included patients < 21 years of age who underwent elective suboccipital craniectomy and C1 laminectomy for CM-I with or without duraplasty at a single center from January 2020 to July 2023. A standardized, multimodal postoperative pain protocol was implemented in August 2021 that did not use narcotic patient-controlled analgesia. Pre- and postprotocol cohorts were compared. The primary outcome was average perioperative pain score. Secondary outcomes included postoperative length of stay (LOS), narcotic usage, and antiemetic usage.

RESULTS
Thirty-four children met the inclusion criteria (17 preprotocol, 17 postprotocol). Fifty-three percent were female (18/34). The mean patient age was 7.0 ± 5.0 years. After implementation of the pain protocol, noninferior average pain scores (p = 0.08) and less antiemetic administration (p = 0.048) were found across both surgery types. Equivalent inpatient LOS (p = 0.78), narcotic prescriptions at discharge (p = 0.73), and milliequivalents of morphine used (p = 0.55) were also found. Bone-only decompression was completed in 65% of patients (n = 22/34, 11 in each pre- and postprotocol group) with 12 of 34 undergoing duraplasty (6 in each pre- and postprotocol group). Patients who underwent posterior fossa decompression with duraplasty had a significantly longer LOS (p = 0.003), more overall narcotic usage (p = 0.015), and lower pain scores (p = 0.047) compared with those who underwent decompression without duraplasty.

CONCLUSIONS
Patients undergoing a CM-I decompression had noninferior postoperative pain control and required less antiemetic dosing after implementation of a multimodal pain protocol. Neurosurgeons should consider a postoperative multimodal pain regimen for their patients with CM-I who undergo decompression with or without duraplasty.
Association between pituitary adenoma consistency, resection techniques, and patient outcomes: a single-institution experience
Authors: Guerra Gage A. , Kashif Zain , Cote David J. , Feng Jeffrey J. , Renn Alex , Yang Max , Cheok Stephanie , Peterson Racheal , Shiroishi Mark S. , Carmichael John D. , Zada Gabriel 
Published: January 2025

OBJECTIVE
The present study aimed to investigate the association between pituitary adenoma (PA) consistency and other measurable tumor characteristics, extent of resection (EOR), postoperative complications, and outcomes.

METHODS
In total, 507 PA resections were intraoperatively assigned a consistency grade from 1 (cystic/hemorrhagic tumors) to 5 (calcified tumors) based on intraoperative tumor characteristics. Tumor consistency was analyzed in tertiles (grades 1 and 2, grade 3, and grades 4 and 5) to determine associations with tumor characteristics, EOR, recurrence, postoperative outcomes, and complications.

RESULTS
The cohort in this study included primarily macroadenomas (93.3%) comprised mostly of nonfunctional PAs (NFPAs) (79.5%), with 77.1% showing suprasellar extension, 16.6% showing infrasellar invasion, and 46.4% showing cavernous sinus invasion (CSI). PA consistency grades were as follows: grade 1 or 2 (40.6%), grade 3 (39.3%), and grade 4 or 5 (20.1%). Compared with grade 1 or 2, higher-consistency PAs were more common in men (p = 0.001) and trended toward lower rates of gross-total resection (GTR) (67.6% vs 53.5%, p = 0.06). Higher PA consistency was predictive of any postoperative complication (OR 1.23, 95% CI 1.05–1.43; p = 0.009), specifically including transient diabetes insipidus (DI) (OR 1.45, 95% CI 1.12–1.85; p = 0.004) and cranial nerve (CN) paresis (OR 3.45, 95% CI 1.56–7.69; p = 0.002). Higher consistency was a strong predictor of CN palsy (OR 3.33, 95% CI 1.52–7.30; p = 0.004) for NFPAs. Higher-consistency PAs were more frequently adrenocorticotropic hormone–positive in both univariable (OR 1.33, 95% CI 1.11–1.60; p = 0.002) and multivariable (OR 1.38, 95% CI 1.11–1.69; p = 0.004) analyses. Higher consistency was associated with lower rates of GTR on stratification by CSI for Knosp grade 3 (p < 0.001) and grade 4 (p < 0.001) PAs, but not in low-grade (Knosp grades 1 and 2) PAs.

CONCLUSIONS
Tumor consistency is an important consideration for the resection strategy, particularly for PAs with CSI, and a predictor of intraoperative CSF leaks and perioperative complications and outcomes, including EOR, CN paresis, and transient DI.
Mapping the Economic Potential of the Community of Teluk Latak Village, Bengkalis District, Bengkalis Regency through an MSMEs
Authors: Suryanita Reni , Raihan Arditama Harnedi  , Yohannes Firzal  , Benny Hamdi Rhoma Putra  , Yenita Roza  , Poppy Nurmayanti  , Harnedi Maizir  
Published: January 2025

This community service activity (PKM) was carried out in Teluk Latak Village, Bengkalis District, Bengkalis Regency, Riau Province. This activity records the socio-economic potential of Teluk Latak Village which focuses on Micro, Small and Medium Enterprises (MSMEs). Although the majority of residents do not experience problems in doing business, some business actors report difficulties, especially in marketing and promoting the products that have been produced. Therefore, this PKM activity collected data on the economic potential in Teluk Latak Village based on information from MSME players. The PKM activity method is carried out through a field survey involving MSME business actors using the interview method and analyzing data related to the economy. The survey results show that the majority of MSME activists in Teluk Latak Village are engaged in weaving. This finding illustrates the strong economic potential, especially in the weaving MSME sector. It is hoped that the results of data collection on economic potential through this PKM activity can be used as a reference for optimal efforts in developing the potential of Teluk Latak Village. The results of the analysis show that improving marketing and promotion strategies can overcome the obstacles faced by some MSME actors, so that economic development in Teluk Latak Village can be carried out holistically, maximizing the potential of the MSME sector and overcoming obstacles that may arise.
Relative places
Authors: Donnelly Maureen 
Published: January 2025

Newton distinguishes between absolute and relative places. Both types of places endure through time and may be occupied by various objects at various times. But unlike absolute places, each relative place stands in fixed spatial relations with one or more reference objects. Relative places with independent reference objects (e.g., a ship and the earth) may move relative to one another. Relative places, not absolute places, are used to locate objects and track their movements in common-sense reasoning and in disciplines such as biology, engineering, and geology. The purpose of this paper is to develop a formal theory for reasoning about relative places and their changing relations to both other places and to material objects.
CONSIDERAÇÕES SOBRE O (RE)CONHECIMENTO DAS LITERATURAS AFRICANAS DE LÍNGUA PORTUGUESA NA EDUCAÇÃO BÁSICA
Authors: Dias Mariana Sousa 
Published: January 2025

Este artigo discute o papel Literaturas Africanas em Língua Portuguesa como um dos pilares da educação libertadora no século XXI. Buscaremos verificar até que ponto esse referencial, como recurso pedagógico, contribui para que estudantes da educação básica estejam aptos não somente a conhecerem suas próprias origens, mas também a tomarem consciência quanto a seu potencial interventivo diante das iniquidades sociais.
De redes y antigüedades.
Authors: Gómez Vázquez Ulises A. 
Published: January 2025

La presente propuesta es una reseña crítica del libro de Achim Miruna, Ídolos y antigüedades. La formación del Museo Nacional de México (1825-1867), trad. De Rodrigo Martínez Baracs, Alicia García Bergua, Miruna Achim.- Primera edición, Ciudad de México: Secretaria de Cultura, INAH, 2021, 328 pág., ISBN: 978-607-539-577-7. Se presenta la estructura narrativa y los principales matices y enfoques de la obra.
ESTIMATION OF THE RELATIONSHIP BETWEEN SOLAR RADIATION, RELATIVE HUMIDITY, AND TEMPERATURE IN UGWOLAWO USING LINEAR REGRESSION ANALYSIS
Authors: Ohiani Alexander O. , Ayodele S. A. , Egbunu F. , Ibrahim A. R. , Oshatuyi I. I. , Adeyemi J. O. 
Published: January 2025

The radiation of the sun has a critical climatic influence on solar energy generation, ecology and crop production. Consequently, it is important to know how solar radiation interacts with other climate variables such as temperature and relative humidity towards developing better designs of solar arrays and mitigate the impact of climate variability. In this study, we have explored the impacts of relative humidity and temperature on the sun’s radiation. The statistical data for this work was collected from the trustworthy National Aeronautics and Space Administration (NASA) power archive. Shortwave solar radiation, relative humidity and temperature readings from January 1991 to December 2020 were retrieved and evaluated to establish average values. The results showed that the annual relative humidity ranged from 77.25% to 83.94%, while the annual temperature fluctuated between 24.86°C and 26.58°C, and the radiation from sun varied from 4.72 to 5.40 kW-hr/m². Both graphical and statistical analyses using a simple regression model indicated a slightly direct correlation between solar radiation and relative humidity while data regarding temperatures and solar radiation during the analysis period demonstrated an inverse relationship.
The lymphocyte levels of Hashimoto thyroiditis patients were significantly lower than that of healthy population
Authors: Xue Hui , Xu Ruyi 
Published: January 2025

Background and purposeHashimoto thyroiditis (HT) is an autoimmune disease without infectivity. We compared the differences of blood lymphocytes levels between HT patients and healthy people.Patients and methodsThis study included a total of 84 HT patients whose thyroid function was normal and 60 HT patients with abnormal thyroid function. A corresponding number of medical examination population in our hospital were randomly selected as the control groups. White blood cell count, neutrophil count, neutrophil percentage, lymphocyte count, and lymphocyte percentage were compared between HT patients and healthy population. The correlations between TSH, FT4 and above parameters were further tested.ResultsWe found significant differences between HT with normal thyroid function group and control group in lymphocyte count (P&lt;0.001), lymphocyte percentage (P&lt;0.001) and neutrophil percentage (P&lt;0.001), but no differences in sex (P=0.134), age (P=0.200), white blood cell count (P=0.315) and neutrophil count (P=0.790). Significant differences were observed in neutrophil count (P=0.032), neutrophil percentage (P=0.010), lymphocyte count (P=0.010) and lymphocyte percentage (P&lt;0.001) between HT with abnormal thyroid function group and control group, but not in sex (P=0.769), age (P=0.060) and white blood cell count (P=0.156) between the two groups. There were significant differences in white blood cell count (P=0.009) and neutrophil count (P=0.032) between HT patients in the normal thyroid function group and HT patients in the abnormal thyroid function group. Neither FT4 nor TSH was associated with lymphocyte levels or neutrophil levels.ConclusionsThe lymphocyte levels in HT patients were significantly lower than healthy population. The neutrophil count in HT patients with regular thyroid function was lower than those in abnormal thyroid function HT patients.
Research hotspots and trends in the application of electroencephalography for assessment of disorders of consciousness: a bibliometric analysis
Authors: Chen Jiawen , Shi Yanhua , Dong Zhao , Xu Feng , Zhou Mengyu , Zhu Jing , Gao Jie , Liu Su 
Published: January 2025

ObjectiveDisorders of consciousness (DoC) result from severe traumatic brain injury and hypoxia or ischemia of brain tissues, leading to impaired perceptual abilities. Electroencephalography (EEG) is a non-invasive and widely applicable technology used for assessing DoC. We aimed to identify the research hotspots in this field through a systematic analysis.MethodsRelevant studies published from January 1, 2004 to December 31, 2023 were retrieved from the Web of Science Core Collection database. The data were analyzed and visualized using CiteSpace, VOSviewer, and SCImago Graphica.ResultsIn total, 1,639 relevant publications were retrieved. The country with the highest number of publications was the United States, the most productive institution was Harvard University, the journal with the highest output was Clinical Neurophysiology, and the journal with the highest total number of citations was Neurology. The author with the most publications was Steven Laureys and the most common keyword was “vegetative state.”ConclusionThe field is undergoing rapid development, characterized by a proliferation of advanced technologies and an increased emphasis on international collaboration. The document offers an impartial perspective on the advancements of the research study for the benefit of the researchers.
Ternary PEO/PVDF-HFP-Based Polymer Electrolytes for Li-Ion Batteries
Authors: Nguyen Hoang Bao Tran , Ding Ling , Pohle Björn , Schmeida Toni , Nguyen Hoang Bao An , Mikhailova Daria 
Published: January 2025

The impetus to study and develop polymer electrolytes for metal-ion batteries is due to their enhanced safety compared to flammable organic liquid electrolytes, promising ionic conductivity, and broad electrochemical stability window, making them to viable candidates for battery application. In the current work, we present a simple fabrication procedure and a comprehensive physico–chemical study of various PVDF-HFP-based electrolyte formulations with a sufficient addition of PEO polymer, LiTFSI conducting salt, and EMIMTFSI ionic liquid. The ionic conductivity, activation energy for ionic movement and thickness of the resulting polymer electrolyte show a non-linear dependency on the PVDF-HFP/PEO ratio. The electrolyte composition with a 0.35PEO-0.65PVDF-HFP/1LiTFSI/1EMIMTFSI mass fraction exhibits the highest ionic conductivity among the compositions, revealing 7.7×10−5 S cm−1 at 30 °C. Electrochemical tests in half full and full Li-ion batteries with a LiFePO4 cathode and Li4Ti5O12 anode also emphasized this composition as the most promising one, providing an initial capacity in full cells of 120 mAh g−1 and a capacity retention of about 75% after 50 charge/discharge cycles at a 0.1 C current rate. In the PEO/PVDF-HFP polymer blend with EMIMTFSI as a plasticizer, the amount of crystalline parts, which are detrimental to a fast ionic diffusion, is significantly reduced.
Crues, partie I : Rôle du karst dans les crues du fleuve Lez
Authors: Fleury Perrine , Kong-A-Siou Line , Johannet Anne , Darras Thomas , Pistre Séverin , Guilhalmenc Marc , Maréchal Jean-Christophe , Dörfliger Nathalie 
Published: January 2025

Le système karstique du Lez est soumis à une gestion active de fait de son exploitation par pompage en amont de son exutoire principal sur le drain, à un débit supérieur à son débit d'étiage. L'étude de son comportement hydrogéologique en relation avec les débits du fleuve Lez à Montpellier en période de crue a permis de développer un schéma conceptuel de fonctionnement de l'ensemble du système en prenant en considération les interactions entre les écoulements de surface et le fleuve. Ainsi, il est apparu que le système karstique peut jouer le rôle d'écrêteur de crue, en stockant une quantité significative d'eau (pouvant aller jusqu'à un équivalent de 1 50 mm de précipitations) lorsqu'il est «déprimé» (du fait des pompages en période estivale). Alors qu'une fois saturé, le système karstique contribue à amplifier la crue, l'ensemble des précipitations participe à l'augmentation des débits du fleuve. Cette augmentation des débits a été identifiée sous le terme «composante karstique». Elle correspond, une fois le karst saturé, à une augmentation du ruissellement de surface alimentant le fleuve. Ce phénomène est associé à (i) un refus à l'infiltration vers l'aquifère et également (ii) à des transferts rapides en souterrain vers l'aval hydraulique via le réseau karstique en charge notamment au niveau d'exutoires temporaires (sources de trop-plein) alimentant le réseau de surface. Une modélisation des niveaux piézométriques et des débits à la source du système karstique du Lez a été réalisée afin de proposer un nouvel outil de gestion en période de crues. Deux modèles ont été développés. Le premier est un modèle réservoir construit à partir du schéma conceptuel de fonctionnement, le second étant un modèle à réseau de neurones. Les résultats issus de ces deux approches sont complémentaires et permettent, en fonction des scénarios de pompage et de pluie, d'anticiper les niveaux dans le karst et donc la capacité d'écrêtage mais aussi de prévoir les débits à la source.
En plus de cette compréhension du rôle du système karstique sur la crue de surface, un abaque de vigilance des débits a été établi. Il permet d'anticiper l'évolution piézométrique à la source et la quantité de pluie qui contribuera directement à la crue de surface.
Émile Delacroix, 1847, la première thèse de karstologie !
Authors: Gauchon Christophe 
Published: January 2025

En janvier 1847, Émile Delacroix, professeur à l’École préparatoire de médecine de Besançon, soutient à Paris une thèse de science intitulée : Notice sur les sources et les cavernes et en particulier sur quelques sources du département du Doubs.
Ce texte bref, d’une douzaine de pages, envisage successivement ce qu’il appelle l’hydrographie souterraine et les variations de température. Dans la première partie, É. Delacroix pose les bases d’une théorie de la formation des cavernes. On sait peu de choses sur la vie d’É. Delacroix et sur la façon dont il a pu travailler ; une ou deux indications laissent à penser qu’il s’est lui-même rendu sur le terrain, ne serait-ce que pour les mesures de température. Et c’est sur la base de quelques observations en surface et sous terre qu’il énonce ses hypothèses sur le creusement des cavernes. Rien n’indique non plus qu’il ait continué à s’intéresser au sujet après la soutenance de sa thèse. Cette Notice de 1847, année où ne furent soutenues en France que quatorze thèses de science dont celles de Louis Pasteur et de Charles Lory, reste à notre connaissance la première thèse sur la question des cavernes, et donc la première occurrence de cette question dans la production académique. Or É. Delacroix est resté jusqu’à ce jour un quasi-inconnu, seul Trevor Shaw y fait une très brève allusion dans son History of cave Science. Il s’agit donc de replacer l’apport d’É. Delacroix dans cette proto-karstologie mal connue de la première moitié du XIXe siècle, après les travaux de N. Desmarest, d’A. N. Parandier et de J. Desnoyers, et bien avant le traité d’A. Daubrée sur les eaux souterraines.
L’art pariétal paléolithique de la grotte aux Points d’Aiguèze : définition d’un dispositif pariétal singulier et discussion de ses implications
Authors: Monney Julien 
Published: January 2025

Points cave palaeolithic rock art : discussing its spatial organization and its implications
Located in the middle of the Ardèche river gorges (southern France), Points cave contains some rock art attributed to the Upper Palaeolithic, including : series of large dots, animals’ representations, bilobed signs, and an angular sign. An in-depth description and analysis of the rock art and its iconographic and technic characteristics is given here, along with a thorough examination of the structural links that may exist between the different pieces of rock art. Through a discussion of the formal homogeneity vs. diversity of this rock art assemblage, it gives the opportunity to tackle the issues of spatial organization and chronocultural identity. This article concludes to the strong cultural association between palm-dots and bilobed signs and to the presence of a very similar rock art assemblage in some specific sectors of Chauvet cave. Using the concept of “iconographic project” it points out the inner chronocultural consistence of Points cave rock art, but the possible coexistence of, at least, two different iconographic projects in Chauvet cave, eventually leading to question the chronocultural homogeneity of its rock art.
Imagerie LiDAR et cartographie semi-automatique de l’exokarst de la Montagne de Reims (Champagne, France)
Authors: Berthe Julien , Lejeune Olivier , Devos Alain , Bollot Nicolas 
Published: January 2025

LiDAR imaging and semi-automatic mapping of the exokarst of the Montagne de Reims (Champagne, France).
Reims Mountain has a lithostratigraphic contact karst whose exokarst has been mapped for a long time on its northern slope. However, the south slope had never really been investigated because of the inaccessibility of the land held under private hunting property. The use of LiDAR imagery