bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Thematic Analysis of Narratives About Birth Satisfaction and Health Awareness From Postnatal Women Who Have High and Low Trauma Scores on thePosttraumatic Stress Disorder Checklist
Authors: Emmens Berbel , Martin Caroline J. Hollins , Patterson Jenny , Martin Colin R. 
Published: October 2023

BACKGROUND:Around one-third of women experience childbirth trauma, with 3%–15% developing postpartum posttraumatic stress disorder (PP-PTSD).AIM:Explore birth satisfaction and health perception across two groups of postnatal women with either high or low trauma scores.METHOD:Forty postnatal women were divided into groups dependent upon Posttraumatic Stress Disorder Checklist (PCL-5) scores: high severity (n= 20; range 25–57) or low severity (n= 20; range 0–7). Semi-structured interviews explored women’s childbirth experiences related to birth satisfaction and reports of postnatal health. Thematic analysis was performed.FINDINGS:Narrative content differed appreciably between high (A) and low (B) scoring groups. Group A narratives were more negative (A1: Overall, a negative recall), referencing lack of autonomy, support, or being heard (A2: Missing needs) and negative influences (A3: Disrupting my bubble). Group B recalled more birth satisfaction (B1: Mostly positive recall) associated with (B2: Autonomy; B3: Being cared for; B4: Intuition, instinct, and primal force). Group A narratives focused strongly on mental health (A4: Reduced awareness; A6: Experiencing PTSD; A7: Needing help), with some focus on physical health (A5: How I feel physically); Group B spoke less about health (B5: My health).DISCUSSION:High-quality psychological care during labor, with continuity, choice, support, and control, alongside postnatal health follow-up may improve birth satisfaction and reduce the incidence of PP-PTSD.CONCLUSION:To increase birth satisfaction and reduce trauma, maternity care providers must be supported to prioritize high-quality psychological care to women during labor, providing choice, control, and continuity within trusting relationships. Trusting relationships are key to ongoing conversations regarding health and seeking/receiving help. Routine birth satisfaction screening and education for care providers about signs of trauma are important.
Prevalence of Neglect and Abuse During Labor and Delivery in a Tertiary Hospital
Authors: Ghoneim Hanan M. , Taha Omima T. , Elgedawy Asmaa M. 
Published: October 2023

BACKGROUND:Childbirth is a significant event with a great impact on maternal physical and psychological health. Childbirth abuse has been reported in different countries with variable rates. This study aims to determine the prevalence of childbirth abuse during labor in a governmental hospital in Egypt.METHODS:This cross-sectional study was conducted from March 2020 to December 2021. We recruited 190 women. Patients were asked to fill in the Arabic-validated childbirth verbal abuse and neglect questionnaire immediately after delivery. The questionnaire consisted of four parts enquiring about personal data and childbirth history, the occurrence of physical violence, and other elements of satisfaction.RESULTS:Fifty (26.3%) patients were neglected during childbirth. Verbal abuse was reported by 25.8%. Two women (1.1%) were slapped (physical abuse) during childbirth. Women reported being satisfied and strongly satisfied at 57.9% and 37.9%, respectively. Multiparity (p-value .02), patient ignorance about the childbirth process (p-value .004), their rights (p-value .0001), and lack of participation in decision-making (p-value .0001) were associated with exposure to neglect. Verbal abuse was associated with the delivery time in addition (p-value .004).CONCLUSION:Neglect and abuse occurred significantly at the current facility.
The Effect of Substitution of Snakehead Fish and Purple Eggplant Flour on The Acceptability of Biscuits for Stunting Prevention
Authors: Misnati Misnati , Pomalingo Anna .Y , Ranti Irza Nanda , Nuryani Nuryani 
Published: October 2023

The development of supplementary food formulas for toddlers made from local foods can be an alternative in handling child nutritional problems. Purpose of study was to observe the acceptability of biscuits substitution of snakehead fish meal and purple eggplant flour. Design of study was an quasi experimental using postest only control group design with four treatments namely substitution of snakehead fish meal and purple eggplant flour. The ratio of wheat flour, fish meal and purple eggplant flour is 100%: 0 : 0,85% : 10% : 5%, 70% : 20% : 10%, and 55% : 30% : 15%. The results of the study based in the color characteristic the highest score after control was F1 (score = 2.47), the taste aspect F1 (score = 2.7), the aroma aspect F1 (score = 2.41), thetexture/crunch F1 (score = 2.65). There was an effect of substitution of snakehead fish meal and purple eggplant flour on color acceptability (p = 0.000) and taste (p = 0.003), there is no effect of substitution of snakehead fish meal and purple eggplant flour on aroma receptivity (p = 0.306) and crispness (p = 0.155). In conclusion, there are significant differences in the color and taste characteristics of cookies substitution of snakehead fish flour and purple eggplant flour between F0, F1, F2 and F3.
Multiple Wolbachia subpopulations co-occur in single Culex pipiens mosquito organs
Authors: Schrieke Hans , Duron Olivier , Trouche Blandine , Eren A. Murat , Reveillaud Julie 
Published: October 2023

Abstract
Wolbachia is a maternally inherited intracellular bacterium that infects a wide range of arthropods including mosquitoes. The endosymbiont is widely used in biocontrol strategies due to its capacity to modulate arthropod reproduction and limit pathogen transmission.
Wolbachia infections are generally assumed to be monoclonal within individual hosts. By reconstructing Wolbachia genomes from naturally-infected single individual Culex pipiens mosquitoes from both ovary and midgut metagenomes, here we show that an ancestral Wolbachia population can evolve to a set of closely related but genetically distinct subpopulations which coexist within the same hosts and are maternally transmitted to host progeny. Our analysis of Wolbachia population genetics within and between organs across individual mosquitoes from Southern France revealed consistent single-nucleotide and single-amino acid variants that we could confirm in egg metagenomes from Northern Africa locations. The striking occurrence of SNVs at identical positions within protein-coding genes in independent and geographically distant samples suggest that the observed Wolbachia genomic variants are potentially important for the biology of the endosymbiont. Overall, the presence of multiple co-existing Wolbachia subpopulations in individual mosquitoes may have critical implications on the use of Wolbachia in fundamental and applied research.
An exercise and patient education intervention to reduce pain and physical limitations in individuals with developmental dysplasia of the hip: study protocol for a process evaluation integrated within a randomised controlled trial (the MovetheHip trial)
Authors: Jacobsen Julie , Evans Rhiannon , Morgan Kelly , Thorborg Kristian , Oestergaard Lisa Gregersen , Sørensen Dorthe 
Published: October 2023

Abstract
Background
The Movethehip trial investigates the effectiveness of an exercise and patient education intervention for adults with developmental dysplasia of the hip. The intervention involves eight tailored one-to-one sessions with trained providers who employ supportive feedback tools. This protocol reports a planned process evaluation, which aims to determine how the intervention functions by examining mechanisms of change, implementation of the intervention (process, dose and reach), its acceptability and the influence of contextual factors.
Methods
Two hundred trial participants aged 18–50 years will be recruited from a University Hospital in Denmark and randomised to the intervention or control group. Approximately ten providers will deliver the intervention. The process evaluation adopts a concurrent mixed-methods design. The mechanisms of change will be explored through semi-structured one-to-one interviews (at baseline and six-month follow-up) with 15–20 purposefully sampled participants and by measuring changes in health outcomes (self-reported pain, physical functioning and quality of life completed at baseline and at three- and six-month follow-up). The implementation will be assessed using self-report questionnaires (at baseline and six-month follow-up), training records and semi-structured focus group interviews with intervention providers (n = 10) and healthcare managers (n = 4–6). Additionally, change will be measured through an explorative examination of associations between dose and change in health outcomes, applying simple linear regression models. The acceptability of the intervention and the influence of contextual factors will be explored through one-to-one participant interviews and focus group interviews with 4–6 healthcare managers. The interviews will focus on expectations, experiences, events, personal understandings and interaction with interpersonal and organisational aspects. Interview data will be analysed using theoretical thematic analyses, and findings will be merged with quantitative data and reported jointly on a theme-by-theme basis.
Discussion
The process evaluation conducted as part of the MovetheHip trial will illuminate how the intervention works, and if the intervention is proven effective, the findings of the evaluation will contribute to pinpoint how the intervention may be optimised to facilitate future up-scaling and implementation.
Trial registration
The MovetheHip protocol was approved by the Committee on Health Research Ethics in the Central Denmark Region. ClinicalTrials, NCT04795843, 20 March 2021, https://classic.clinicaltrials.gov/ct2/show/NCT04795843.
In vivo quantification of programmed death-ligand-1 expression heterogeneity in tumors using fluorescence lifetime imaging
Authors: Kumar Anand , Pal Rahul , Krishnamoorthy Murali , Matsui Aya , Kang Homan , Morita Satoru , Taniguchi Hajime , Kobayashi Tatsuya , Morita Atsuyo , Choi Hak Soo , Duda Dan 
Published: October 2023

Abstract
Cancer patient selection for immunotherapy is often based on programmed death-ligand-1 (PD-L1) expression as a biomarker. PD-L1 expression is currently quantified using immunohistochemistry, which can only provide snapshots of PD-L1 expression status in microscopic regions of ex vivo specimens. In vivo imaging using targeted agents can capture dynamic variations of PD-L1 expression in entire tumors within and across multiple subjects. Towards this goal, several PD-L1 targeted molecular imaging probes have been evaluated in murine models and humans. However, clinical translation of these probes has been limited due to a significant non-specific accumulation of the imaging probes and the inability of conventional imaging modalities to provide quantitative readouts that can be compared across multiple subjects. Here we report that in vivo time-domain (TD) fluorescence imaging can provide quantitative estimates of baseline tumor PD-L1 heterogeneity across untreated mice and variations in PD-L1 expression across mice undergoing clinically relevant anti-PD1 treatment. This approach relies on a significantly longer fluorescence lifetime (FLT) of PD-L1 specific anti-PD-L1 antibody tagged to IRDye 800CW (αPDL1-800) compared to nonspecific αPDL1-800. Leveraging this unique FLT contrast, we show that PD-L1 expression can be quantified across mice both in superficial breast tumors using planar FLT imaging, and in deep-seated liver tumors (> 5 mm depth) using the asymptotic TD algorithm for fluorescence tomography. Our results suggest that FLT contrast can accelerate the preclinical investigation and clinical translation of novel molecular imaging probes by providing robust quantitative readouts of receptor expression that can be readily compared across subjects.
Short-term temporal variability in offshore benthic biodiversity across hydrographic regions at a Sub Antarctic archipelago
Authors: Puccinelli Eleonora , Logston Renae , Russo Cristina S. , Ansorge Isabelle J. , Meden Charles E. O. von der 
Published: October 2023

Abstract
Community composition is one of the main factors influencing the ecological functioning of any given ecosystem, with a more diverse community providing a larger set of services. Benthic community composition can vary at spatial and temporal scales, with the dynamics of primary production and benthic food availability being key determinants of community structure of a given system. Studies have indicated shifts in benthic community composition at Sub Antarctic Islands over a period of 30 years, linked to variability in food availability driven by climate change. Here we aim to evaluate possible short-term variability in benthic community composition at the Sub Antarctic archipelago Prince Edward Islands (PEIs), sampling stations across three hydrographically dynamic regions over two consecutive years, 2016–2017. The results indicated significantly higher species richness and abundance in 2017 than in 2016, with some taxa also showing variation among regions around the PEIs. Such effects can be linked to different substratum type or hydrographic regime. This study further contributes to understanding variability and changes in benthic communities in the near future, an essential information to develop efficient management strategies for this vulnerable marine system.
Comparison of Fetomaternal Outcome in Women With Preterm Premature Rupture of Membranes on Expectant Management Versus Delivery at 34 Weeks
Authors: JHA SHAILJA KUMARI , BACHANI SUMITRA , SALUJA SUMITA , CHELLANI HARISH K , BHARTI REKHA , MUKHERJEE BIJOYA , SURI JYOTSNA 
Published: October 2023

Abstract
Purpose
To study feto-maternal outcomes in women with preterm prelabour rupture of membranes (PTPROM) on expectant management versus delivery at 34weeks of gestation and correlate period of latency and inflammatory markers with delivery outcomes. We have chosen this research topic as there is paucity of specific guidelines regarding the optimal period of gestation for delivering women with PTPROM.
Methods
Prospective observational study conducted on 262 women with PTPROM from 28–33 + 6weeks of gestation. Women were monitored till 37weeks with biweekly total leukocyte count (TLC) and weekly C reactive protein (CRP), urine routine microscopy (URM), urine culture, high vaginal culture (HVS) sensitivity and ultrasound. Women were monitored expectantly till 37 weeks however intervention was done at any time during feto-maternal compromise. Feto-maternal outcomes were documented.
Result
Amongst the study group 238 (90.8%) women were managed expectantly while 24 (9.1%) required intervention. A latency of 3-4weeks was observed in 131(50%) women. Chorioamnionitis developed in 13(4.9%) and 5.7% neonates developed sepsis however both had no correlation with the latency period. Neonates who developed sepsis (5.7%) were comparable in both the groups (p = 1.000). Early neonatal death (END) occurred in 10 (3.8%) amongst which seven died because of Low birth weight (LBW), two due to sepsis and one due to respiratory distress. LBW was significantly associated with END(p < 0.001).
Conclusion
Expectant management beyond 34 weeks with close monitoring can improve the neonatal outcomes without increasing maternal morbidity in women with PTPROM.
Induced Superconductivity in Hybrid Au/YBa2Cu3O7-x Electrodes on Vicinal Substrates
Authors: Gundareva Irina , Martinez-Castro Jose , Tautz Frank , Grützmacher Detlev , Schäpers Thomas , Lyatti Matvey 
Published: October 2023

Abstract
Superconducting electrodes are an integral part of hybrid Josephson junctions used in many applications including quantum technologies. We report on the fabrication and characterization of superconducting hybrid Au/YBa2Cu3O7 − x (YBCO) electrodes on vicinal substrates. In these structures, superconducting CuO2-planes face the gold film, resulting in a higher value and smaller variation of the induced energy gap compared to the conventional Au/YBCO electrodes based on films with the c-axis normal to the substrate surface. Using scanning tunneling microscopy, we observe an energy gap of about 10–17 meV at the surface of the 15- nm-thick gold layer deposited in situ atop the YBCO film. To study the origin of this gap, we fabricate nanoconstrictions from the Au/YBCO heterostructure and measure their electrical transport characteristics. The conductance of the nanoconstrictions shows a series of dips due to multiple Andreev reflections in YBCO and gold providing clear evidence of the superconducting nature of the gap in gold. We consider the Au/YBCO electrodes to be a versatile platform for hybrid Josephson devices with a high operating temperature.
Quantitative prediction of rate constants and its application to organic emitters
Authors: Kaji Hironori , Shizu Katsuyuki 
Published: October 2023

Abstract

Many phenomena in nature consist of multiple elementary processes. If we can predict all the rate constants of each process quantitatively, we can comprehensively predict and understand various phenomena in nature. Here, we report that it is possible to quantitatively predict all related rate constants and quantum yields without conducting experiments, using multiple-resonance thermally activated delayed fluorescence (MR–TADF) as an example. MR–TADF is desirable for practical application in organic light-emitting diodes (OLEDs) because of their narrow emission spectra, high luminescence efficiency, and chemical stability. However, MR–TADF emitters have one drawback: slow reverse intersystem crossing (RISC), leading to efficiency roll-off and reduced device lifetime. We first showed a quantum chemical calculation method for quantitatively reproducing all experimentally obtained rate constants and quantum yields for previously synthesized MR–TADF emitters. Next, this method was applied to presently unsynthesised molecules. This study reveals a strategy to improve RISC without compromising other important factors: rate constant of radiative decay, photoluminescence quantum yields, and emission linewidth. Our method is robust and can be applied in a wide range of research fields—not only for quantitative prediction of rate constants and quantum yields but also for a comprehensive understanding of the mechanism including the time evolution of excitons.
Supra-inguinal fascia iliaca compartment block versus Pericapsular nerve group block-lateral femoral cutaneous nerve block combination after hip arthroplasty: a randomized controlled trial
Authors: Tian Yuan , Yuan Yuxin , Hu Zhouting , Li Wangyu , Li Kai 
Published: October 2023

Abstract
Background: Total hip arthroplasty can cause moderate and severe pain that can have a profound impact during postoperative rehabilitation. Regional nerve block is recommended for anesthesia and analgesia during hip surgery. In particular, the iliac fascia space block of the inguinal ligament is a widely used technique in clinical practice that can block the femoral nerve trunk, obturator nerve trunk, and lateral femoral cutaneous nerve simultaneously. This study aimed to compare the effect of supra-inguinal fascia iliaca compartment block (S-FICB) to a combination of pericapsular nerve group block (PNGB) and lateral femoral cutaneous nerve block (LFCNB) on block range and analgesia as well as motor function of patients with total hip arthroplasty.
Methods: Sixty patients undergoing total hip arthroplasty through posterolateral approach were randomly divided into two groups with 30 patients each. After complete awakening from general anesthesia, patients received ultrasound-guided S-FICB with 40 mL 0.4% ropivacaine (group S) or 20 mL 0.4% ropivacaine PNGB combined with 3 mL 0.4% ropivacaine LFCNB (PL group). We used the Numerical Rating Scale and cumulative dosage of sufentanil to grade pain during the first 48 h. Quadriceps femoris muscle and adductor muscle strength, range of sensory block, length of stay, and complications were also recorded.
Results: No significant differences were found in analgesic indicators of both groups (P＞0.05). The Numerical Rating Scale scores of resting pain at each time point after the blockage were significantly lower than those before the blockage (P＜0.05). However, the PL group had significantly less incidence of analgesia sensation in the anterior and medial side of the thigh (P<0.05), and less incidence of quadriceps and adductor weakness (P＜0.05) at 1 h and 6 h after the blockage compared to that in group S.
Conclusions: Compared to S-FICB, the combination of PNGB and LFCNB provided equivalent analgesic effect and significantly lowered the risk of numbness and muscle weakness of the thigh. This combination can be used as a new option in multimodal analgesia after total hip arthroplasty.
Trial registration: Chinese Clinical Trial Registry (no. ChiCTR2200055963, date of registration: 29/01/2022)
Parental obesity, health determinants, and cardiometabolic risk according to sleep duration in schoolchildren: analysis through structural equations
Authors: Brand Caroline , Lemes Vanilson Batista , Sehn Ana Paula , Agostinis-Sobrinho Cesar , Henriquez-Maquehue Fernanda , Saldía Emilio Jofré , Ibacache-Saavedra Paulina , Farias-Valenzuela Claudio , Villa-González Emilio , Reuter Cézane Priscila 
Published: October 2023

Abstract

Background: the independent association between parental obesity, sleep and lifestyle habits with cardiometabolic risk factors in children and adolescents have been widely explored in the literature. Our study represents a novel approach to comprehensively investigate a complex model encompassing various aspects associated with cardiometabolic risk in youth. Thus, the aim of the present study was to verify the relationship between parental obesity and cardiometabolic risk in children and adolescents, considering the mediator role of health indicators according to sleep time.
Methods: This cross-sectional study was conducted on 3,973 children and adolescents aged 6 to 17 years, attending public and private schools in a city located in Southern Brazil. Sleep duration, lifestyle, physical activity, natural food consumption, and parental obesity were evaluated through self-reported questionnaires. Physical fitness was evaluated according to the protocols of Projeto Esporte Brasil. The body fat percentage was evaluated through the measures of tricipital and subscapular folds, and body mass index was calculated. The clustered metabolic risk score (cMetS) considered the summing z-scores of waist circumference, systolic blood pressure, triglycerides, total cholesterol/high-density lipoprotein cholesterol ratio, and fasting glucose, divided by five. A structural equation model was applied for statistical analysis.
Results: The relationship between parental obesity and cardiometabolic risk was observed in children and adolescents with adequate sleep, being significant (p<0.05) mediated by physical activity, natural food, physical fitness, and lifestyle. This was also observed when parental education was included in the inadequate sleep cluster model.
Conclusion: Present findings underscore the importance of sufficient sleep duration as a critical factor in understanding the complex interplay between parental obesity and cardiometabolic risk in children and adolescents.