bluuebunny/crossref_metadata_2025_split huggingface dataset:
An Intelligent Customer-Driven Digital Solution to Improve Perioperative Health Outcomes Among Children Undergoing Circumcision and Their Parents: Development and Evaluation
Authors: Kwa Zhi Yin , Li Jinqiu , Loh Dale Lincoln , Lee Yang Yang , Liu Guangyu , Zhu Lixia , Pikkarainen Minna , He Honggu , Mali Vidyadhar Padmakar 
Published: February 2024

Background
Circumcision as a common elective pediatric surgery worldwide is a stressful and anxiety-inducing experience for parents and children. Although current perioperative interventions proved effective, such as reducing preoperative anxiety, there are limited holistic solutions using mobile apps.

Objective
This paper aims to describe the development and primary evaluation of an intelligent customer-driven smartphone-based app program (ICory-Circumcision) to enhance health outcomes among children undergoing circumcision and their family caregivers.

Methods
Based on the review of the literature and previous studies, Bandura’s self-efficacy theory was adopted as the conceptual framework. A multidisciplinary team was built to identify the content and develop the apps. Semistructured interviews were conducted to evaluate the ICory-Circumcision.

Results
The ICory-Circumcision study was carried out from March 2019 to January 2020 and comprised 2 mobile apps, BuddyCare app and Triumf Health mobile game app. The former provides a day-by-day perioperative guide for parents whose children are undergoing circumcision, while the latter provides emotional support and distraction to children. In total, 6 participants were recruited to use the apps and interviewed to evaluate the program. In total, 4 main categories and 10 subcategories were generated from content analysis.

Conclusions
ICory-Circumcision seemed to lean toward being useful. Revisions to ICory-Circumcision are necessary to enhance its contents and features before advancing to the randomized controlled trial.

Trial Registration
ClinicalTrials.gov NCT04174404; https://clinicaltrials.gov/ct2/show/NCT04174404
UNRAVELLING THE INTERACTION BETWEEN GARCINISIDONE-A AND HER2 PROTEIN IN BREAST CANCER: A COMPUTATIONAL STUDY
Authors: FURQAN MAINAL , DACHRIYANUS  , SUSANTI MERI , PUTRA PURNAWAN PONTANA , WAHYUNI FATMA SRI 
Published: February 2024

Objective: One substance found in the leaves of Garcinia cowa Roxb that has anticancer properties is garcinisidone-A. The study aims to simulate the docking of garcinisidone-A (Gar-A), molecular dynamics, and predict the ADME by predicting the binding of the HER2 protein in breast cancer cells and developing new drug candidate options for cancer treatment, often starting with computational analysis.
Methods: The research method involves computational utilization of pkCSM applications, Gar-A docking simulation with the HER2 protein using Gnina software version 1.0.2, and molecular dynamics conducted with GROMACS 2022.2 and CHARMMGUI applications.
Results: Gar-A has a molecular weight of less than 500, a Log P value of greater than 5, a limited amount of water solubility, a low level of skin permeability, good intestinal permeability, and a Convolutional Neural Network (CNN) pose score on the HER2 protein of 0.6178. It also does not readily cross the blood-brain barrier, and total clearance values indicate rapid elimination via other excretory routes or enzyme metabolism. Gar-A is thought to have interactions with HER2. There are hydrogen bond interactions with amino acids Lys753 and Asp863, carbon-hydrogen bonds with amino acids Leu785, Ser783, Thr862, and alkyl bonds with amino acids Leu726, Leu852, and Ile767. The stability of the Gar-A-substrate interaction could have been more evident during 100 ns molecular dynamics simulation.
Conclusion: The physicochemical properties of Gar-A align with Lipinski's rule for drug candidates. ADME predictions indicate good intestinal permeability for Gar-A; however, it suggests it cannot penetrate the blood-brain barrier. The docking results reveal that Gar-A has a value close to one which indicates similar action to its natural ligand and molecular dynamics simulations that Gar-A is less stable. The results illustrate that Gar-A has the potential as a breast anticancer.
ANTIOXIDANT ACTIVITY OF THE ACTIVE FRACTION OF MANGOSTEEN RIND EXTRACT (GARCINIA MANGOSTANA)
Authors: WIDAYANTI ARI , JUFRI MAHDI , SURINI SILVIA , ELLYA BERNA 
Published: February 2024

Objective: Determination of the IC50 value of the active Fraction was carried out to see the antioxidant activity of the ethanol extract of mangosteen peel (Garcinia mangosteen) Mangosteen peel is known to have very strong antioxidant activity. The research began with maceration of mangosteen peel with ethanol solvent. Then, the mangosteen peel extract was fractionated with three solvents, namely those with different polarities, namely water, dichloromethane, and n-hexane.
Methods: The ethanol extract of mangosteen rind was further fractionated using n-hexane, dichloromethane, and water, then the solvent was removed by evaporation. The three resulting fractions were measured for antioxidant activity using the DPPH method with Quercetin as a comparison. The active Fraction with the highest IC50 value is then compared with the extract, and the comparison is seen with TLC. Next, the Fraction was tested with GC to see the remaining solvent. And then continued with determining alpha mangostin levels in all fractions using UHPLC.
Results: IC50 value for each n-hexane fraction was 50.65µg/ml, the dichloromethane fraction was 34.66µg/ml, and the water fraction was 45.72µg/ml. The results of the solvent test showed that there was no residual solvent in the dichlormethane fraction, as seen from the chromatogram results. The results of the assay showed the following results: n-Hexan fraction 25.18%, DCM fraction 31.23%.
Conclusion: The dichloromethane fraction showed the highest antioxidant activity with the best IC 50 value and had higher levels of alpha mangostin than the water and n-hexane fractions.
Interactive Visualization Dashboard for Exploring Scientific Publications in Indonesia
Authors: Sihombing Andre , Yaniasih  , Indrawati Ariani , Afandi Sjaeful , Ningsih Maha Rahmadani 
Published: February 2024

Numerous bibliometric investigations have been carried out in Indonesia, primarily relying on publication data indexed exclusively in Scopus. This study aims to leverage scientific publication data from the Indonesian Scientific Journal Database (ISJD) by constructing an interactive visualization dashboard for the analysis of Indonesian scientific publications. This dashboard is expected to become an additional reference for researchers in the field of bibliometrics. The stages of making this dashboard consist of Identification of visualization needs referring to previous research; data feasibility check; data correction and update; data visualization; and evaluation to assess the correctness of the data and the resulting visualization. Evaluation results indicate that the dashboard's analysis system is functioning effectively, offering diverse analysis options. Nonetheless, the system has limitations related to data quality in ISJD, necessitating improvements in terms of completeness, appropriateness, and data updates. Future research will enhance the dashboard by incorporating citation analysis calculations to evaluate the performance of authors and journals.
The Role of Effluent Analysis and Culture in Diagnosis and Monitoring of Peritoneal Dialysis-Related Peritonitis
Authors: Indrasari Nuri Dyah , Ali Najib 
Published: February 2024

Peritoneal Dialysis (PD) is one of the available renal replacement therapy options for End-Stage Renal Disease (ESRD). One of the most common complications of PD is peritonitis. A 13-year-old boy was admitted to the hospital due to cloudy effluent and abdominal pain four days before admission. He was diagnosed with ESRD in 2015 and has undergone Continuous Ambulatory Peritoneal Dialysis (CAPD) since 2017. The physical examination findings were as follows: the temperature was 36.6 C, the conjunctiva was anemic, the abdomen was tender, and both of the lower extremities were edematous. Peritoneal dialysis effluent analysis showed yellow and turbid effluent with a leukocyte count of 13.346 cells/µL and polymorphonuclear (PMN) cells predominance (69.3%), effluent and serum urea of 221 and 243 mg/dL, effluent and serum creatinine of 16.7 and 18.26 mg/dL, respectively. Effluent Gram stain showed increased leukocytes without bacteria, while effluent culture showed the growth of Methicillin-sensitive Staphylococcus aureus. According to the International Society of Peritoneal Dialysis 2022 guidelines, all criteria for infective peritonitis in this patient were met: clinical features (turbid effluent and abdominal pain), increased cell count (>100 cells/µL) with PMN >50%, and positive effluent culture. The patient was administered intravenous Ampicillin-Sulbactam based on the effluent culture and antimicrobial susceptibility testing. Serial effluent analyses suggested a return-to-normal trend in leukocyte and PMN counts. After 18 days of hospitalization, the patient was allowed to discharge based on clinical and laboratory improvements.
HbA1c As Diabetes Mellitus Biomarker and Its Methods Evolution
Authors: Kurniawan Liong Boy 
Published: February 2024

This literature aims to review various aspects of HbA1c as a Diabetes Mellitus (DM) biomarker and various HbA1c examination methods and their respective advantages and limitations. Diabetes mellitus is a condition characterized by chronic hyperglycemia and can lead to microvascular and macrovascular complications in the future. HbA1c has been used extensively over the last few decades to monitor glycemic control and assess microvascular and macrovascular risk. It has also been used as one of the diagnostic criteria for DM. HbA1c is hemoglobin A, which is glycated at the N terminal of its valine beta-globin chain and provides an overview of glycemic control over the past three months. HbA1c is often reported using % or mmol/mol units and can be adjusted to assess the average blood glucose level over the past three months. Various methods developed for HbA1c examination include immunoassay, boronate affinity, enzymatic, capillary electrophoresis, and Ion-Exchange High-Performance Liquid Chromatography (IE-HPLC), and each has its advantages and limitations. In addition to their advantages in detecting HbA1c, the capillary electrophoresis and IE-HPLC methods can also detect other types of hemoglobin and the presence of hemoglobin variants.
Environmental Education of Tourists for Sustainable Tourism Development
Authors: Šimková Eva , Kořínková Barbora , Obršálová Kristýna 
Published: February 2024

Abstract
In line with the concept of sustainable development, the paper deals with the issue of environmental education and training to increase the awareness of tourism participants of their own responsibility for the practical implementation of sustainable tourism. The aim is to map the behavior of tourism participants and to propose some sustainable behavior principles in the form of a miniguide. The motto of the miniguide is not to simply see travel as just fun, or passive source of information, but as an incentive to learn about nature, culture and customs of local people, to promote and deepen language and other skills, including active protection of the environment. The miniguide might also be an incentive to sustainable tourism development. An important aspect of putting the principles of sustainability into practice is to publish and disseminate these principles so that they become freely available to the general public. That may be through information materials, educational signs, social networks, etc. Spreading awareness of the need to protect nature and the countryside will help to make people aware of their own responsibility for our common future.
Online Three-Dimensional Bin Packing: A DRL Algorithm with the Buffer Zone
Authors: Zhang Jiawei , Shuai Tianping 
Published: February 2024

AbstractThe online 3D bin packing problem(3D-BPP) is widely used in the logistics industry and is of great practical significance for promoting the intelligent transformation of the industry. The heuristic algorithm relies too much on manual experience to formulate more perfect packing rules. In recent years, many scholars solve 3D-BPP via deep reinforcement learning(DRL) algorithms. However, they ignore many skills used in manual packing, one of the most important skill is workers put the item aside if the item is packed improperly. Inspired by this skill, we propose a DRL algorithm with a buffer zone. Firstly, we define the wasted space and the buffer zone. And then, we integrate them into the DRL algorithm framework. Importantly, we compare the bin utilization with di erent thresholds of wasted space and di erent buffer zone sizes. Experimental results show that our algorithm outperforms existing heuristic algorithms and DRL algorithms.
Writing the History of French Translation in the 21st Century. Towards a New Paradigm?
Authors: Eiben Ileana Neli 
Published: February 2024

Abstract
To write the history of translation in the digital age, we must devise and use new analytical tools. Starting from this premise, this study proposes to examine the ways in which recent technologies influence (the quality of) research in the history of translation as well as to discuss scientific work that seeks to “modernize” the history of translation in accordance with contemporary trends. By adopting a descriptive approach, I will review several traditional materials and instruments of analysis that can be identified in the specialized literature, and then I will move on to modern ones. A corpus of academic texts about the history of French translation serves my purposes well, given the existence of a large body of translation studies of “French expression” produced since the latter half of the 2oth century by numerous Francophone researchers. Main preliminary findings show that we can witness a paradigm shift and that research in the history of translation must change and adapt itself to the current developments that have impacted every field of work.
Literary translation in the era of digital humanities and the questioning of the primacy of the source text: for a memography of Molière's translations
Authors: Tushar Iyengar Chandniée C. 
Published: February 2024

Abstract
The article focuses on the role of Digital Humanities in the creation of a new cyberinfrastructure that relies on the concept of Translation Memory (TM) to create advanced tools in Computer Assisted Translation (CAT). In this new cyberinfrastructure, the source text is broken down into segments and cannot exist in isolation at the same time as older translations act as new source material. The article explores the possibility of establishing a transmedial cartography of the transfer of meaning in literary translations using the notion of a “memographie” prevalent in Digital Humanities. Modelled on hybrid databases, facilitating the creation of tropes in literary language not only from the source text but also from past translations, memographies can facilitate the enhancement of the creative power of the translator in future literary translations. The article uses short extracts from Anglo-American translations of Molière in its case studies, starting from The Playhouse to be Let by Sir William D'Avenant, staged in 1663, up to more recent translations by Richard Wilbur. This is done to illustrate the functioning of the source text and target text coupling in a memorographic plexus that could serve as a new starting point in literary information retrieval systems.
Efficient Road Traffic Video Congestion Classification Based on the Multi-Head Self-Attention Vision Transformer Model
Authors: Khalladi Sofiane Abdelkrim , Ouessai Asmâa , Benamara Nadir Kamel , Keche Mokhtar 
Published: February 2024

Abstract
Due to rapid population growth, traffic congestion has become one of the major issues in urban areas. The utilization of technology may help to address this issue. This paper proposes a new Multi-head Self-attention Vision Transformer (MSViT) based macroscopic approach, for road traffic congestion classification. To evaluate this approach, we use the UCSD (University of California San Diego) dataset that includes different weather conditions (clear, overcast and rainy) and different traffic scenarios (light, medium and heavy). The classification accuracy reached a high level of 99.76% with this dataset and 99.37% when night-mode frames are added to it. The proposed MSViT based method outperforms the state-of-the-art macroscopic and microscopic methods that have been evaluated using the same UCSD dataset, which makes it an efficient solution for traffic congestion prediction.
Computational Fluid Dynamics Analysis of Flow Characteristics and Heat Transfer Variabilities in Multiple Turbine Blade Cooling Channels
Authors: Elmenshawy Adham Ahmed Awad Elsayed , Alomar Iyad , Arshad Ali , Medvedevs Aleksandrs 
Published: February 2024

Abstract
In the realm of gas turbine engine technology, turbine blades are persistently subjected to extreme thermal conditions due to prolonged exposure to high-temperature gases. Given this operating environment, devising effective cooling strategies is paramount for ensuring the turbine’s safety and longevity. Despite the critical nature of this issue, existing literature scarcely addresses cooling channels that incorporate factors like variable cross-sectional attributes and rotational effects. In this study, Computational Fluid Dynamics (CFD) and numerical methodologies were employed to analyze the flow mechanism and performance of three distinct cooling channels characterized by variable cross-sectional features. The results indicate a marginal thermal performance improvement of up to 3% for U-shaped cooling channels, specifically at a Reynolds number of 20,000, in comparison to Net cooling channels. Conversely, jet impingement channels outperform U-shaped channels by an impressive margin of over 11%. Additionally, at a Reynolds number of 60,000, jet impingement cooling channels manifest a significant upsurge of nearly 25% in the ratio between average Nusselt number, and the reference Nusselt number when compared with U-shaped and Net cooling channels.
<p>Análisis de la sentencia del Tjue Kamberaj contra el Istituto per L’edilizia Sociale de Bolzano: una perspectiva desde las resistencias a la tutela multinivel de los derechos humanos</p>
Authors: Palomares Herrera Manuel 
Published: February 2024

La presente obra corresponde a un estudio de los orígenes de la figura de protección multinivel, su recepción e inclusión en los sistemas de protección de derechos humanos, especialmente en el europeo y el americano; así como una mirada a la efectividad y beneficios que ha reportado su aplicación.
En contraposición, se trata también de un análisis de las problemáticas y retos que han surgido con la misma, los cuales han sido advertidos desde casos originarios, como en el asunto denominado Servet Kamberaj contra el Instituto para la Vivienda Social de la Provincia Autónoma de Bolzano; en el cual se ubicó al juzgador en una posición de dicotomía frente a la interrogante de ¿Cuál derecho de conformidad con su nivel espacial de protección, se debe aplicar en cada caso concreto?
Lo anterior, con miras a resaltar la importancia de una figura, la cual ha tenido su principal desarrollo en el modelo europeo y cada vez más impacto y acogida en el escenario americano.
أثر بعض المتغيرات الإنتاجية على إنتاج محصول الحنطة في العراق للمدة (2004-2019)
Authors: عبدالله حاتم نجم , خليل محمود حميد 
Published: February 2024

يُعَد محصول الحنطة من المحاصيل الرئيسة إذ تحتل الحنطة المرتبة الاولى من حيث المساحة المزروعة والأهمية الغذائية في كل دول العالم ومنها العراق، وتعد زيادة انتاج محصول الحنطة هدفا لكل اقتصاد رشيد متخلف أو متقدم على السواء، ان دراسة انتاج الحنطة التي تعاني من تدني وتذبذب مستمرين وتشخيص اسباب تدنيها وتذبذبها وصولاً الى ايجاد أفضل السبل لزيادة الانتاج وتحسينه يعد من الامور المهمة التي تستحق الدراسة، إذ يشهد العراق عجزاً في انتاج محصول الحنطة ومن هذا المنطلق جاءت مشكلة البحث، ولقد اعتمد الدراسة على فرضية مفادها اثر بعض المتغيرات الانتاجية على انتاج محصول الحنطة في العراق تكون لها اثار إيجابية على زيادة الإنتاج وتحسين نوعية وكذلك أثار سلبية تؤدي الى انخفاض إنتاجه في حال عدم استخدامها بأسلوب علمي، وهدفت الدراسة الى معرفة بعض المتغيرات الانتاجية وتحديد العوامل المؤثرة على انتاج محصول الحنطة في العراق للمدة (2019-2004) والعمل على وضع عدد من الحلول الممكنة لمعالجة المشاكل التي تواجه انتاج هذا المحصول المهم للنهوض بواقع إنتاجه كماً ونوعاً.
Financial Crimes: The concepts, Transformations and Effects
Authors: Al-Sayigh Nameer Ameer 
Published: February 2024

This research addresses the financial crime methodology from concepts, emerging, content and implications that it leaves in the economy and financial system, as financial markets are their primary source, and the financial system with its structures, processes and financial instruments is an absorbent pump for these crimes, and it is made more difficult and a great challenge to face them is the increase of their types and associations and that the technical factor has contributed significantly to their spread, specifically after the year (2005).The research also focused on a range of proposed treatments drawn from the experiences of states, systems and markets that can reduce their effects and not prevent them from occurring completely by tracking the financial crime cycle, The research has reached a set of conclusions, perhaps the most important of which is, Increasing the cost of action to combat this kind of crimes, such as commitment costs, recruitment and training of human resources, and that they (Financial Crimes) are not stopped by political or geographic boundaries, but extend through the reach and spread of financial transactions as the research also found a series of proposals, the most important of which was the need to establish channels for financial, international and regional cooperation more effectively than before, so as to contribute to the provision of reliable, timely and credible information on activities and events that are classified as financial crimes.
تأثير استراتيجية الصيرفة الشاملة في تحسين الأداء المالي باستخدام مؤشري الربحية والسيولة دراسة تطبيقية في مصرفي الرافدين والرشيد فرع البصرة
Authors: والي علي قدوري , عكار زينب شلال 
Published: February 2024

تهدف الدراسة إلى الكشف إلى قياس دور استراتيجية الصيرفة الشاملة في تحسين الأداء المالي في مصرفي الرافدين والرشيد فرع البصرة، من خلال دراسة تحليلية لآراء عينة عشوائية من موظفي المصارف المذكورة آنفًا، للوقوف على تصورات الموظفين في تطبيق استراتيجية الصيرفة الشاملة في هذه المصارف، ومقدرتهم على توفير متطلبات تطبيقها وعلاقة ذلك في تحسين الأداء المالي. ومن أجل تحقيق هذه الأهداف فقد تمت صياغة نموذج فرضي يُعبر عن العلاقات المنطقية بين متغيرات الدراسة إذ عُدت استراتيجية الصيرفة الشاملة متغيرًا مستقلًا يؤثر في الأداء المالي بوصفه متغيرًا مُعتمدًا، وبغية الكشف عن طبيعة العلاقات المتمثلة في أنموذج الدراسة فقد اتجهت الدراسة الحالية إلى استنباط فرضية رئيسة، وبالاعتماد على المنهج الوصفي التحليلي فقد جرى ترتيب استمارة استبانة لجمع البيانات، وتم استهدف مجتمع الدراسة بشكل فعلي من خلال عينة من موظفي مصرفي الرافدين والرشيد فرع البصرة، وبأسلوب العينة العشوائية البسيطة تم توزيع (350) استمارة استبانة وكان عدد الاستبانات المُسترجعة (312) استمارة، اما الصالحة للتحليل الإحصائي فقد كانت (270) استمارة استبانة بمعدل استجابة 77)%) وقد تم الاعتماد على البرنامج الاحصائي ((SPSS v.23 لغرض تحليل البيانات.
وقد خرجت الدراسة بنتائج حول وجود علاقة تأثر معنوية بين استراتيجية الصيرفة الشاملة والأداء المالي، لأنها تمتلك استراتيجية وأنشطة مصرفية تؤثر إيجابيًا في عمل المصارف وترفع مستوى أدائها بالطريقة التي تمكنها من تحقيق أرباح أعلى ومخاطر أقل.