bluuebunny/crossref_metadata_2025_split huggingface dataset:
Teatros anatómicos: Padua, Barcelona y París: la conciencia del cuerpo en la arquitectura
Authors:   , Galeno Ibaceta Claudio 
Published: October 2023

La historia de la conciencia del cuerpo en la arquitectura y las artes, desde los asclepeiones
griegos hasta los hospitales modernos, fue consolidada por la investigación anatómica y
desarrollada con mayor precisión en arquitecturas destinadas al saber del cuerpo: los teatros
anatómicos. Estos espacios fueron organizados entorno a la disección anatómica,
centralizados en el cadáver, y oscilaron entre el ocultamiento y la pública escenificación de la
performance anatómica, cobijando desde el hombre renacentista hasta el higienista hombre
ilustrado. Esas arquitecturas reflejaban las ambiciones de los anatomistas o cirujanos que las
gestaron, pero además reflejan el espíritu del tiempo en cuanto a su diseño. Mediante tres
obras de arquitectura situadas entre los siglos XVI y XVIII, se puede comprender el medio
donde se desarrollaron estas escenas de producción en torno a la conciencia del cuerpo y de
su espacio: en Padua, con el anfiteatro gestionado por Girolamo Fabrici d’Acquapendente y
atribuido a Dario Varotari; en Barcelona, ejecutado por Pere Virgili y Ventura Rodríguez; y en
París, erguido gracias a Germain Pichault de La Martinière y Jacques Gondoin
The history of body consciousness in the architecture and the arts, since the Greek
asclepieion to modern hospitals, was strengthened by the anatomical research and developed
more accurately in the architecture for the knowledge of the body: the anatomical theaters.
These spaces were organized around anatomical dissection, based at the corpse, and ranged
between concealment and public staging of the performance anatomy, sheltering from the
renaissance man to the hygienist illustrated man. These architectures for theaters reflected
the ambitions of the anatomists or surgeons who originated them, but also reflect the spirit of
the times in terms of design. By three works of architecture located between the sixteenth and
eighteenth century, is possible to understand the context in which these scenes were
developed around the production of body consciousness and its space: Padua, with the
amphitheater negotiated by Girolamo Fabrici d’Acquapendente and attributed to Dario
Varotari; Barcelona, executed by Pere Virgili and Ventura Rodriguez, and Paris, build by
Germain Pichault de La Martinière and Jacques Gondoin.
Emilio Duhart Harosteguy, un arquitecto integral : 1935-1992
Authors:   , Esparza Saavedra Verónica 
Published: October 2023

Through a panoramic view, this document aims to explain Emilio Duhart as a complete architect, a professional who develops simultaneously different facets in his work, being also concise and consistent with the Modern Movement principies that inspires his way.
These facets, extensively analyzed, refer to Duhart as student, architec, urban planner and academic which accompanied by his writings are intended to demostrate how each one of his projects and interest try to consciously translate the ideas of the rationalist architecture to the chilean reality, achieving a harmonious and coherent adaptation to the power of the Andean country landscape and the local idiosyncrasy. Duhart is considered one of the most relevant architects of Latin America; he is directly linked to the cutting edge referents and endowed with the design skills that can bring together different scales an complexities.
A través de una mirada panorámica se pretende explicar a Emilio Duhart como un arquitecto integral, es decir, un profesional que desarrolla varias facetas de su quehacer profesional de manera simultánea, sintética y consecuente con los principios del movimiento moderno que lo inspiran. Dichas facetas, analizadas en extenso, se refieren al Duhart estudiante, arquitecto, urbanista y académico, que acompañadas de sus escritos tienen por objeto demostrar cómo en cada uno de sus proyectos e intereses traslada las ideas de la arquitectura racionalista de vanguardia europea a la realidad de Chile de manera consciente y sintética. Logrando una adaptación armónica y coherente con la potencia paisajística del pals andino y la idiosincrasia local. Duhart es considerado uno de los arquitectos más relevantes de Latinoamérica, vinculado directame nte a los referentes de vanguardia, y dotado de una capacidad proyectual capazde aglutinar diferentes escalas y complejidades.
Mecánica de estructuras
Authors: Cervera Ruiz Miguel , Blanco Díaz Elena Irma 
Published: October 2023

Conté: 1. Resistencia de materiales 2. Métodos de análisis
La obra Mecánica de estructuras está concebida como libro de texto para estudiantes de ingeniería civil y mecánica que se inicien en el estudio de esta materia. Su enfoque, claramente pedagógico, tiene como objetivo exponer con claridad y rigor los principios fundamentales de la materia, de forma que sirvan de base para estudios posteriores, más especializados en dicha disciplina. La comprensión de los diferentes temas viene facilitada por la inclusión de numerosos ejemplos resueltos. La publicación completa consta de dos volúmenes. En el libro 1 (Resistencia de Materiales) se abordan los fundamentos de la teoría de la elasticidad y de la resistencia de materiales, y se estudian los diferentes estados de deformación y tensión de las piezas de estructuras de barras. En el libro 2 (Métodos de análisis) se presentan los métodos de resolución de las estructuras de barras y se plantea los métodos de compatibilidad y equilibrio; de este último se incluye también la versión matricial (método de rigidez).
Termodinàmica estadística. Vol. 2. Aplicacions i bases fisicomatemàtiques: una introducció amb problemes resolts i comentats
Authors: Besalú i Llorà Emili 
Published: October 2023

Conté: 1. Fonaments i funcions de partició: una introducció amb problemes resolts i comentats. 2. Aplicacions i bases fisicomatemàtiques: una introducció amb problemes resolts i comentats
Aquest llibre és una introducció a la termodinàmica estadística i s’ha orientat de forma especial a aplicacions químiques. Ateses les dificultats, essencialment conceptuals, que presenta aquest cos teòric, en cada capítol es parteix d’una teoria general que s’amplia i s’exemplifica en els exercicis comentats. Els apèndixs han estat concebuts com a elements alternatius de consulta complementària. En adoptar aquest format es pretén aproximar el lector, de forma progressiva i també constructiva, al contingut de la disciplina mitjançant una obra didàctica i autocontinguda. El text s’estructura en tres parts: la primera, de fonaments; la segona, dedicada al càlcul de funcions de partició, i la darrera, més extensa, d’aplicacions de la termodinàmica de l’equilibri. A part d’impartir una sèrie de conceptes d’aplicació general, l’objectiu més important que s’ha perseguit és que el lector s’apropi als continguts d’una part de la ciència que, tradicionalment, ha presentat dificultats tant en el moment de ser ensenyada pels docents com de ser entesa pels alumnes.
Cerrahi Hemşireliği İntörn Öğrencilerinin Mezuniyet Öncesi ve Sonrası Hemşirelik İmaj Algılarının Karşılaştırılması
Authors: KOÇAK Furkan , DEMİRSOY Büşra Yeşim , DİZLEK BAYRAKTAR Defne , ÇATAL Emine 
Published: October 2023

Amaç: Bu araştırmada, cerrahi hemşireliği intörn öğrencilerinin mezuniyet öncesi ve sonrası hemşirelik imaj algılarının karşılaştırılması amaçlanmıştır.
Yöntem: Araştırma tanımlayıcı türdedir. Araştırmanın örneklemini bir hemşirelik fakültesi son sınıfta Cerrahi Hastalıkları Hemşireliği İntörn Uygulaması Dersi alan 32 öğrenci oluşturmuştur. Araştırma grubunda yer alan bir öğrenci örneklem dışı bırakılmıştır. Veri toplama sürecinde araştırmacılar tarafından hazırlanan Kişisel Bilgi Formu ile Hemşirelik İmaj Ölçeği kullanılmıştır. Veriler mezuniyet öncesi yüz yüze görüşme tekniğiyle, mezuniyet sonrası ise online e-posta yoluyla toplanmıştır.
Bulgular: Araştırmaya katılan öğrencilerin yaş ortalaması 22.37 ±0.12, %84.4’ü kadındır. Hemşirelik bölümüne isteyerek gelme oranı %75.0, tercih sıralamasında 1. olanlar %59.4 iken öğrencilerin % 65.6’sının ailesinde hemşire bulunmamaktadır. Ayrıca %68.8’i hemşirelik eğitimi öncesi hastanede bir hemşireden bakım aldığını belirtmiştir. Araştırma sonuçlarına göre cerrahi hemşireliği intörn öğrencilerin Hemşirelik İmaj Ölçeği toplam puanları mezuniyet öncesi 74.50 ± 4.78 (Min:59, Max:82) iken, mezuniyet sonrası 71.53± 8. 19 (Min:34, Max:80) olarak bulunmuştur. “Genel Görünüm” alt boyutunda 16.34 ±1.78’den (Min:13, Max:20), 14.37±1.87’e (Min:10, Max:18), “İletişim” alt boyutunda 15.78 ± 2.66’dan (Min:7, Max:18), 15.53 ± 2.73’e (Min:6, Max:18); “Mesleki ve Eğitsel Nitelikler” alt boyutunda 42.62 ± 2.32’den (Min:35, Max:45) 41.37 ± 4.88’e (Min:17, Max:45) değiştiği saptanmıştır. Mezuniyet öncesine göre mezuniyet sonrası toplam ölçek ve tüm alt boyutlarda puanların düştüğü ancak sadece “Genel Görünüm” alt boyutunda istatistiksel olarak anlamlı derecede düşük olduğu saptanmıştır (p
الصورة الفنيّة في شعر سالم الكلباني
Authors: فهد بن سيف بن علي المنذري  
Published: October 2023

تمثل الصورة الجزء التأثيري الأهم في الوظيفة الشعرية "فالصورة أول ما ندركها تشغلنا، وتستقطب اهتمامنا بذلك التجاوز الدلالي الذي لا نعثر عليه بالكم والكيف نفسهما في الكلام العادي"[1]، وبها تتجسّد شخصية المبدع في ذهن المتلقي، ولكنها لا تؤدّي دورا ذا أهمية إلا بالائتلاف الجمعي بين النظائر المُشكـــِّلة لها، ونقصد به الترابط بين الألوان البلاغية بعضها ببعض، فالتشبيه وحده غير كافٍ لإعطاء آفاق واسعة على الدلالة المقصودة، لكنّه يصبح فاعلا ونفاذا إذا شدّت من أصره الاستعارة والكناية مثلا، أو غيرهما من الأبواب البلاغية الأخرى، فالصورة قد تبقى مُجزية مقبولة باقتِصارها على تقنية واحدة دون سواها، وإن ْ وردت مُطابِقة لــمُقتضى الحال، لكنها لا تحمل بعدا تصويريا عميقا، كما أن تكثيف الأوجه البلاغية حول المعنى الواحد، يفتح نوافذ متعددة للتأويلات حول النص، وللوقوف على التشكيلات الجمالية للصورة البيانية عند الكلباني وللتعرف على مؤشرات رُجوح شكل معين على آخر، ستكون دراستها من ثلاثة جوانب: التشبيه والاستعارة و الكناية، ولا يفوتني التسليم ُ بأن الخــُـــلاصات البلاغية التي سنقبل على دراستها إنما تمثل ذائقة الباحث ومدى إحساسه الفني في استملاح صورة واستهجان أختِها، وأن أمر َ التفاوت في تقييم الصورة أمر بَــدَهي قد يعود إلى اختلاف مشارب المعرفة و روافد الثقافة.
اثر المناخ التنظيمي على أداء الموارد البشرية (دراسة ميدانية على مديرية تربية محافظة كركوك)
Authors: عبدالباسط محمد طاهر محمود الجبوري  , الدّكتورة رشا صالح  
Published: October 2023

هدفت هذه الدّراسة لمعرفة "اثر المناخ التنظيمي على أداء الموارد البشرية في مديرية تربية محافظة كركوك في العراق". وتمّ اختيار أسلوب التّحليل الوصفي، وحُدّد مجتمع الدّراسة بكافّة الموظّفين في مديرية تربية محافظة كركوك للعام (2022-2023)، وجرى إعداد استبيان كأداة لجمع المعلومات، شمل مجالين، الأوّل، تناول اثر المناخ التنظيمي، وتكوّن من (25) فقرة ، والثّاني، تناول أداء الموارد البشرية وتكون كذلك من(25) فقرة، وتحقق له الصّدق والثّبات، ونفِذ على عيّنة تم اختيارها بموجب طريقة العينة الطبقية العشوائية، بلغت (134) فردًا من موظّفي الأقسام والعاملين في المديرية ، وحُددت الوسائل الإحصائيّة (SPSS) المناسبة لتحليل البيانات. وأسفرت النّتائج عن وجود علاقة ارتباط معنوية بين المناخ التنظيمي وأداء الموارد البشرية ، وأن كل الأبعاد التّابعة للمناخ التنظيمي، لها دور في تحسين أداء الموارد البشرية، ،و أوصى الباحث بضرورة تقديم الدّعم المالي من اجل توفير مناخ تنظيمي مناسب في المديرية من اجل تحسين اداء العاملين والقيام بتطوير البرامج التدريبية المقدمة لهم، و نشر الوعي من اجل تحسين الأداء الوظيفي للعاملين.
Levels of Physical Activity at Age 10 Years and Brain Morphology Changes From Ages 10 to 14 Years
Authors: Estévez-López Fernando , Dall’Aglio Lorenza , Rodriguez-Ayllon María , Xu Bing , You Yueyue , Hillman Charles H. , Muetzel Ryan L. , Tiemeier Henning 
Published: October 2023

ImportancePhysical activity may promote healthy brain development in children, but previous research was predominantly cross-sectional and included small samples, providing limited knowledge.ObjectiveTo investigate the longitudinal associations of physical activity with brain morphology changes.Design, Setting, and ParticipantsA 4-year longitudinal population-based cohort study in Rotterdam, the Netherlands, embedded in Generation R, a cohort from fetal life onward. From the women enrolled during pregnancy, children who had repeated measures of brain structure at ages 10 (range 8 to 12) years and 14 (range 13 to 15) years were included. Data were collected from March 2013 to November 2015 (baseline) and from October 2016 to January 2020 (follow-up). Data were analyzed from April to December 2022.ExposureAt age 10 years, both the child and their primary caregiver reported the child’s levels of physical activity with regard to sport participation, outdoor play, and total physical activity. Primary analyses were based on an average multi-informant report.Main outcomes and measuresBrain morphology was quantified by magnetic resonance imaging. Hypothesized regions of interest were the bilateral amygdala and hippocampal volumes. Global brain measures were studied to test the specificity of the hypothesis.ResultsData were available for 1088 children (566 girls [52%]; 693 [64%] Dutch). Their mean (SD) age at baseline was 10.1 (0.6) years. For amygdala volume change, positive associations with multi-informant reports of total physical activity (β = 2.6; 95% CI, 0.3-4.9) were found. Total physical activity was associated with hippocampal volume increases only when reported by the child (β = 3.1; 95% CI, 0.4-5.8). No robust associations with global brain measures were found.Conclusions and relevanceIn this cohort study of 1088 children, more physical activity at 10 years was consistently associated with an increase in amygdala volume in children aged 10 to 14 years. Physical activity and increases in hippocampal volume were found using child reports of physical activity only. These findings suggest physical activity in late childhood was prospectively associated with volumetric changes in specific subcortical structures, but not to global brain development, from late childhood to early adolescence. These findings may inform the design of future public health interventions to best facilitate neurodevelopment with physical activity.
Racial and Ethnic Disparities in Glycemic Control Among Insured US Adults
Authors: Zakaria Nora I. , Tehranifar Parisa , Laferrère Blandine , Albrecht Sandra S. 
Published: October 2023

ImportancePoor access to care and lack of health insurance are important contributors to disparities in glycemic control. However expanding health insurance coverage may not be enough to fully address the high burden of poor glycemic control for some groups.ObjectiveTo characterize racial and ethnic disparities in glycemic control among adults with private and public insurance in the US over a 15-year timeframe and to evaluate whether social, health care, and behavioral or health status factors attenuate estimates of disparities.Design, Setting, and ParticipantsThis cross-sectional study used data from the National Health and Nutrition Examination Survey from 2003 to 2018. Participants included Hispanic or Latino, non-Hispanic Black, and non-Hispanic White adults aged 25 to 80 years with self-reported diabetes and health insurance. Data were analyzed from January 15 to August 23, 2023.ExposureParticipants self-identified as Hispanic or Latino, non-Hispanic Black, or non-Hispanic White.Main Outcomes and MeasuresThe main outcome, poor glycemic control, was defined as glycated hemoglobin A1c (HbA1c) of 7.0% or greater. Information about social (education, food security, and nativity), health care (insurance type, routine place for health care, insurance gap in past year, and use of diabetes medications), and behavioral or health status (years with diabetes, waist circumference, and smoking) factors were collected via questionnaires.ResultsA total of 4070 individuals (weighted mean [SE] age, 61.4 [0.27] years; 1970 [weighted proportion, 49.3%] were women) were included, representing 16 337 362 US adults, including 1146 Hispanic or Latino individuals (weighted proportion, 13.2%), 1196 non-Hispanic Black individuals (weighted proportion, 15.7%), and 1728 non-Hispanic White individuals (weighted proportion, 71.1%). In models adjusted for age, sex, and survey year, Hispanic or Latino and non-Hispanic Black individuals had significantly higher odds of poor glycemic control than non-Hispanic White individuals (Hispanic or Latino: odds ratio [OR], 1.46; 95% CI, 1.16-1.83; Black: OR, 1.28; 95% CI, 1.04-1.57). There was some attenuation after adjustment for social factors, especially food security (Hispanic or Latino: OR, 1.39; 95% CI, 1.08-1.81); Black: OR, 1.39; 95% CI, 1.08-1.81). However, accounting for health care and behavioral or health status factors increased disparities, especially for Hispanic or Latino individuals (OR, 1.63; 95% CI, 1.24-2.16), with racial and ethnic disparities persisting even among those with private insurance (OR, 1.66; 95% CI, 1.10-2.52).Conclusions and RelevanceIn this cross-sectional study of insured adults with diabetes in the US, disparities in poor glycemic control persisted despite adjustment for social, health care, and behavioral factors. Research is needed to identify the barriers contributing to poor control even in populations with access to care.
Heterogeneity and Utility of Pharmaceutical Company Sharing of Individual-Participant Data Packages
Authors: Hopkins Ashley M. , Modi Natansh D. , Abuhelwa Ahmad Y. , Kichenadasse Ganessan , Kuderer Nicole M. , Lyman Gary H. , Wiese Michael D. , McKinnon Ross A. , Rockhold Frank W. , Mann Aaron , Rowland Andrew , Sorich Michael J. 
Published: October 2023

ImportanceThe pharmaceutical industry has made substantial investments in developing processes for sharing individual-participant data (IPD) from clinical trials. However, the utility and completeness of shared IPD and supporting documents must be evaluated to ensure the potential for scientific advancements from the data sharing ecosystem can be realized.ObjectiveTo assess the utility and completeness of IPD and supporting documents provided from industry-sponsored clinical trials.Design, Setting, and ParticipantsFrom February 9, 2022, to February 9, 2023, 91 of 203 clinical trials supporting US Food and Drug Administration registrations of anticancer medicines for the treatment of solid tumors from the past decade were confirmed as eligible for IPD request. This quality improvement study performed a retrospective audit of the utility and completeness of the IPD and supporting documents provided from the 91 clinical trials for a planned meta-analysis.ExposuresRequest for IPD from 91 clinical oncology trials indicated as eligible for the request.Main Outcomes and MeasuresThe utility and completeness of the IPD and supporting documents provided.ResultsThe IPD packages were obtained from 70 of 91 requested clinical trials (77%). The median time to data provision was 123 (range, 117-352) days. Redactions were observed in 18 of the acquired IPD packages (26%) for outcome data, 11 (16%) for assessment variables, and 19 (27%) for adjustment data. Additionally, 20 IPD packages (29%) lacked a clinical study report, 4 (6%) had incomplete or missing data dictionaries, and 20 (29%) were missing anonymization or redaction description files. Access to IPD from 21 eligible trials (23%) was not granted.Conclusions and RelevanceIn this quality improvement study, there was substantial variability within the provided IPD packages regarding the completeness of key data variables and supporting documents. To improve the data sharing ecosystem, key areas for enhancement include (1) ensuring that clinical trials are eligible for IPD sharing, (2) making eligible IPD transparently accessible, and (3) ensuring that IPD packages meet a standard of utility and completeness.
Quantitative Chemical Proteomics Reveals Triptolide Selectively Inhibits HCT116 Human Colon Cancer Cell Viability and Migration Through Binding to Peroxiredoxin 1 and Annexin A1
Authors: Song Fangli , Li Jinglin , Shi Qiaoli , Wong Yin Kwan , Liu Dandan , Lin Qingsong , Wang Jigang , Chen Xiao 
Published: October 2023

AbstractTriptolide (TPL), a natural product extracted from Tripterygium wilfordii Hook F, exerts potential anti‐cancer activity. Studies have shown that TPL is involved in multiple cellular processes and signal pathways; however, its pharmaceutical activity in human colorectal cancer (CRC) as well as the underlying molecular mechanism remain elusive. In this study, the effects of TPL on HCT116 human colon cancer cells and CCD841 human colon epithelial cells are first evaluated. Next, the protein targets of TPL in HCT116 cells are identified through an activity‐based protein profiling approach. With subsequent in vitro experiments, the mode of action of TPL in HCT116 cells is elucidated. As a result, TPL is found to selectively inhibit HCT116 cell viability and migration. A total of 54 proteins are identified as the targets of TPL in HCT116 cells, among which, Annexin A1 (ANXA1) and Peroxiredoxin I/II (Prdx I/II) are picked out for further investigation due to their important role in CRC. The interaction between TPL and ANXA1 or Prdx I is confirmed, and it is discovered that TPL exerts inhibitory effect against HCT116 cells through binding to ANXA1 and Prdx I. The study reinforces the potential of TPL in the CRC therapy, and provides novel therapeutic targets for the treatment of CRC.
A Review of Acoustic Devices Based on Suspended 2D Materials and Their Composites
Authors: Wan Zhaoyi , Liu Huazhan , Zheng Yuebin , Ma Yuhua , Liu Kehai , Zhou Xu , Liu Chang , Liu Kaihui , Wang Enge 
Published: October 2023

AbstractAcoustic devices play an increasingly important role in modern society for information technology and intelligent systems, and recently significant progress has been made in the development of communication, sensing, and energy transduction applications. However, conventional material systems, such as polymers, metals and silicon, show limitations to fulfill the evolving requirements for high‐performance acoustic devices of small size, low power consumption, and multifunctional capabilities. 2D materials hold the promise in overcoming the development bottleneck of acoustic devices aforementioned, given their atomic‐thin thickness, extensive surface area, superior physical properties, and remarkable layer‐stacking tunability. By suspending the 2D materials, mechanical and thermal disruption from substrate will be eliminated, which will enable the development of new classes of acoustic devices with unprecedented sensitivity and accuracy. In this review, the recent progress of acoustic devices based on suspended 2D materials and their composites, especially applications in the audio frequency, static pressure, and ultrasonic frequency range, is briefly summarized, emphasizing the advantageous properties of suspended 2D materials and related outstanding device performance. Together with the development of 2D membrane synthesis, transfer, as well as microelectromechanical fabrication process, suspended 2D materials will shed light on the next‐generation high‐performance acoustic devices.