bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nasal instillation of povidone‐iodine ameliorates ongoing mucosal inflammation in a pre‐sensitized murine model of Der p1‐induced allergic rhinitis
Authors: Kang Jae‐Yoon , Choi Mi‐Ra , Kim Yong Min 
Published: December 2023

AbstractBackgroundInterleukin (IL)‐33, when cleaved into smaller fragments by proteases, becomes hyperactive, contributing to allergic inflammation. Povidone‐iodine (PVP‐I) is an iodine‐based compound that exhibits antimicrobial properties and inhibits proteases. This study aimed to investigate whether PVP‐I treatment inhibits IL‐33 cleavage, improves allergic rhinitis (AR) symptoms, and suppresses allergic inflammation in a mouse model.MethodsIn vitro experiments using full‐length recombinant human IL‐33 and allergens, including house dust mites or Dermatophagoides pteronyssinus 1, were conducted using western blotting. Fifty BALB/c mice were divided into five groups: control (CON), AR with phosphate‐buffered saline treatment (AR), PVP‐I treatment (AR + PVP), trans‐epoxysuccinyl‐L‐leucylamido(4‐guanidino)butane (E64) treatment (AR + E64), and dexamethasone treatment (AR + Dexa). Nasal symptom scores, including rubbing and sneezing, were measured. The cytokine levels in the nasal lavage fluid (NLF) and the concentration of immunoglobulins in the blood serum were assessed. Nasal mucosa from each group was used for reverse transcriptase‐polymerase chain reaction (RT‐PCR) and histological analyses were conducted.ResultsPVP‐I treatment reduced nasal symptoms, suppressed allergic inflammation, and decreased the levels of IL‐33, IL‐5, and IL‐13 in the NLF and total immunoglobulin E (IgE) and specific IgE in the serum. Histopathological analysis revealed a reduction in the number of eosinophils and goblet cells in the nasal mucosa of the AR + PVP group when compared to the AR group. RT‐PCR and immunofluorescence staining confirmed the downregulation of genes and proteins associated with allergic inflammation.ConclusionsThese findings suggest that nasal irrigation with PVP‐I may be a promising therapeutic option for managing AR by inhibiting IL‐33 activation and suppressing allergic inflammation.
Toward Realization of Universal Quantum Teleportation Using Weak Measurements
Authors: Sabale Vivek Balasaheb , Kumar Atul , Banerjee Subhashish 
Published: December 2023

AbstractIn this manuscript, universal quantum teleportation in the presence of memory or memory‐less dynamics with applications of partial collapse measurement operators is analyzed. These results show that the combined effects of memory or non‐Markovianity, and weak measurements can lead to universal quantum teleportation (UQT). This study involves noise models of physical importance having characteristic Markovian and non‐Markovian regions, allowing one to observe a transition in quantum properties as one switches from non‐Markovian to Markovian dynamics. For this, the effects of different types of non‐Markovianity are characterized for efficient UQT, both due to the retention of correlations for a longer duration and due to information backflow. The memory effects arising from a correlated channel with or without weak measurements are analyzed further. Interestingly, this analysis for a correlated amplitude damping channel shows that memory effects are of significant advantage in minimizing the fidelity deviation. The presence of weak measurements further enhances the realization of UQT in the presence of memory. The ability of memory effects to achieve zero fidelity deviation at non‐zero time is interesting and of experimental importance.
Self‐healing polyurethane based on a substance supplement and dynamic chemistry: Repair mechanisms and applications
Authors: Cao Qi , Zhang Lei , Zhang Fenglei , Wang Danlei , Wu Dongfang , Huang Kai 
Published: December 2023

AbstractThis review systematically summarizes the repair mechanisms and applications of self‐healing polyurethane (SHPU) materials aiming at energy conservation and safety under different repair methods. As of now, the repair methods that have emerged can be divided into two categories: substance landfill and bond repair. In terms of the repair mechanisms for both, the former involves the release of healing agents from micro‐carriers (microcapsules, hollow fibers, and microvascular) to fill the damaged area upon external impact. In contrast, bond repair combines physical and chemical changes triggered by light, heat, and other factors. To achieve efficient self‐healing in this mode, both the reorganization of broken chemical bonds and the high mobility of chain segments are crucial. Reversible covalent bonds and supramolecular interactions, as two branches of aforementioned reversible chemical bonds, share the responsibility for maintaining efficient self‐healing despite infinite cycling. Additionally, multiple synergistic crosslinked networks, special nanomaterials, and microphase separation are often used to solve the problem of incompatible healing efficiency and mechanical strength in bond repair. When the perspective is focused on the application, this gradually improved SHPU with strong potential and comprehensive performance has provided raw materials for many fields related to human development, such as road, architecture, healthcare, and electronic.
Convectively coupled Rossby–Gravity waves in a field campaign: How they are captured in reanalysis products
Authors: Wang Xiaocong , Zhang Minghua 
Published: December 2023

AbstractConvectively coupled equatorial waves are a significant source of atmospheric variability in the tropics. Current numerical models continue to struggle in simulating the coupled diabatic heating fields that are responsible for the development and maintenance of these waves. This study investigates how the diabatic fields associated with Mixed Rossby–Gravity waves (MRGs) are represented in four reanalysis products by using a unique observational dataset from the TRMM‐KWAJEX (Tropical Rainfall Measuring Mission‐Kwajalein Experiment) field campaign. These reanalyses include ERA5, Japanese 55‐year Reanalysis (JRA‐55), Climate Forecast System Reanalysis (CFSR), and Modern‐Era Retrospective Analysis for Research and Applications (MERRA). We found that all four reanalyses captured the MRG structures in winds and temperature, and to a lesser degree in the humidity field except in the boundary layer. However, only the ERA5 and MERRA reanalyses captured the gradual rise and succession of the diabatic heating from boundary layer turbulence, shallow convection, cumulus congestus, and deep convection within the waves. ERA5 is the only product that also captured the gradual rise of the subgrid‐scale vertical transport of moist static energy. All reanalysis products underestimated the diabatic heating from cumulus congestus. Results provide observational basis on what aspects of MRG can be trusted and what cannot in the reanalysis products.
Elaeis guineensisleaves for potential renewable sub‐bituminous coal: Optimization of biochar yield by response surface methodology and product characterization
Authors: Nik Pauzi Nik Nurfatmah Pz , Ramli Nur Aainaa Syahirah , Chan Chung‐Hung , Junaidi Mohd Usman Mohd , Amir Zulhelmi , Yusoff Rozita 
Published: December 2023

AbstractPyrolysis of oil palm biomass residue can convert the rich organic matter in biomass into sustainable green energy, thereby addressing the challenge of surplus oil palm biomass residue generated during cultivation. Nonetheless, the pyrolysis of oil palm leaves (OPLs) has received limited attention. In this study, design of experiment‐response surface methodology (DoE‐RSM) was employed to identify the optimal combination of reaction temperature, residence duration, and nitrogen (N₂) flow rate for maximum biochar yield. The elemental analysis, high heating value (HHV), functional group, morphology, pore structure, and thermal behavior were assessed. By varying the operational parameters using response surface methodology, the biochar yield increased by 32.6–85.3%. TheDoE‐RSMpredicted a theoretical yield of 52.1% at 344 °C, 146 min, and 3.2 scfh N₂ flow rate. The experiment confirmed a comparable yield of 53.7% at the stated parameters. TheHHVof 24.14 MJ kg−1was recorded under optimal conditions, and was comparable to sub‐bituminous and bituminous coal. Fourier transform infrared analysis validated theOPLbiochar by weakeningO‐H, C=O,C‐OH, andC‐Hpeaks. Scanning electron microscopy images revealed enlarged pores and altered morphology in theOPLbiochar. X‐ray diffraction showed lower crystallinity of theOPLbiochar than the feedstock. Raman spectroscopy showed higherID/IG, indicating a more disordered carbon structure in theOPLbiochar. Thermogravimetric analysis confirmed higher temperature for main devolatilization ofOPLbiochar, and the differential thermogravimetric analysis curve pattern resembled that of Mukah Balingan coal. The findings are helpful for an initiative to convert a large amount of leftoverOPLsproduced during cultivation and to turn them into high value‐added material for a sustainable contribution to a circular carbon economy.
Understanding practice with culturally and linguistically diverse children and young people who have experienced domestic and family violence: A practitioner perspective
Authors: Keipert Sally‐Ann , Bastian Carmela 
Published: December 2023

AbstractThere is a dearth of research focused on practice responses with culturally and linguistically diverse (CALD) children and young people experiencing domestic and family violence (DFV). This knowledge gap may result in a lack of professional guidance and clarity for practitioners who work in this complex context. This small‐scale qualitative research study explored practice responses with CALD children and young people. Semi‐structured interviews were conducted with nine practitioners who supported and responded to CALD children and young people and their families at the intersection of DFV and child protection. Data included their practice experience, professional knowledge and practice wisdom. A thematic analysis was used that highlighted the importance of practitioners prioritising the needs of children and young people and navigating the complexities of culture and gender.
In vitro Genotoxicity and In silico Docking Analyses of the Essential Oils of Thuja orientalis
Authors: BOZARI Sedat 
Published: December 2023

AbstractTwo main objectives were pursued to assess the reliability of Thuja orientalis essential oils (TOEO). The first objective was to extract TOEO, analyze them by GC‐MS, and determine their in vitro genotoxicity against selected plants using the RAPD‐PCR method. The second objective was to evaluate the in‐silico toxicity of TOEO. The binding sites and energies of each content was calculated against B‐DNA. In‐silico analyses were performed using a simulation program, AutoDock Vina, and Toxicity Estimation Software Tools. 3‐carene, cedrol, and 2‐pinene were identified as the predominant components. In vitro studies showed that the TOEO had a more significant impact on reducing genomic stability in wheat compared to the amaranth. The lowest stability was determined as 39.78 % in wheat and 53.58 % in amaranth. Cedrol (−5,7 kcal/mol) and selinene (−5,6 kcal/mol) exhibited the highest binding affinity. The toxicity test indicated that components other than cyclohexene may have toxic effects, none of them were predicted to be mutagenic, and LD50 (mol/kg) values could vary between 1.33 and 1.55.
Polar covalent apex‐base bonding in borapyramidanes probed by solid‐state NMR and DFT calculations
Authors: Luder Dominique J. , Terefenko Nicole , Sun Qiu , Eckert Hellmut , Mück‐Lichtenfeld Christian , Kehr Gerald , Erker Gerhard , Wiegand Thomas 
Published: December 2023

AbstractPyramidane molecules have attracted chemists for many decades due to their regular shape, high symmetry and their correspondence in the macroscopic world. Recently, experimental access to a number of examples has been reported, in particular the rarely reported square pyramidal bora[4]pyramidanes. To describe the bonding situation of the nonclassical structure of pyramidanes, we present solid‐state Nuclear Magnetic Resonance (NMR) as a versatile tool for deciphering such bonding properties for three now accessible bora[4]pyramidane and dibora[5]pyramidane molecules. 11B solid‐state NMR spectra indicate that the apical boron nuclei in these compounds are strongly shielded (around −50 ppm vs. BF3‐Et2O complex) and possess quadrupolar coupling constants of less than 0.9 MHz pointing to a rather high local symmetry. 13C−11B spin‐spin coupling constants have been explored as a measure of the bond covalency in the borapyramidanes. While the carbon‐boron bond to the −B(C6F5)2 substituents of the base serves as an example for a classical covalent 2‐center‐2‐electron (2c–2e) sp2‐carbon‐sp2‐boron σ‐bond with 1J(13C‐11B) coupling constants in the order of 75 Hz, those of the boron(apical)‐carbon(basal) bonds in the pyramid are too small to measure. These results suggest that these bonds have a strongly ionic character, which is also supported by quantum‐chemical calculations.
Signal Transduction Allows Temporal Control of the Potential of a Concentration Cell Driven by the Decarboxylation of an Activated Carboxylic Acid
Authors: Capocasa Giorgio , Frateloreto Federico , Correale Cavallari Stefania , Valentini Matteo , Lanzalunga Osvaldo , Di Stefano Stefano 
Published: December 2023

AbstractThe use of Activated Carboxylic Acids (ACAs) allows the time‐controlled operation of dissipative chemical systems based on the acid‐base reaction by providing both the stimulus that temporarily drives a physicochemical change and, subsequently, the counter‐stimulus with a single reagent addition. However, their application is inherently limited to acid‐sensitive systems. To overcome this limitation, we herein develop a straightforward device for the transduction of the acid‐base stimuli delivered by an ACA into a voltage signal that, in turn, is used to control voltage‐sensitive circuits that are not pH‐responsive by themselves. The signal transductor can be easily assembled from common laboratory equipment and employs aqueous solutions of readily available chemicals. Furthermore, the operator can simply and intuitively tune the amplitude of the voltage signal, as well as its duration and offset by varying the concentration of the chemical species involved in the transduction process.
Chord measures in integral geometry and their Minkowski problems
Authors: Lutwak Erwin , Xi Dongmeng , Yang Deane , Zhang Gaoyong 
Published: December 2023

AbstractTo the families of geometric measures of convex bodies (the area measures of Aleksandrov‐Fenchel‐Jessen, the curvature measures of Federer, and the recently discovered dual curvature measures) a new family is added. The new family of geometric measures, called chord measures, arises from the study of integral geometric invariants of convex bodies. The Minkowski problems for the new measures and their logarithmic variants are proposed and attacked. When the given ‘data’ is sufficiently regular, these problems are a new type of fully nonlinear partial differential equations involving dual quermassintegrals of functions. Major cases of these Minkowski problems are solved without regularity assumptions.
Monolignol Potential and Insights into Direct Depolymerization of Fruit and Nutshell Remains for High Value Sustainable Aromatics
Authors: Khan Rabia J. , Guan Jianyu , Lau Chun Y. , Zhuang Huichuan , Rehman Shazia , Leu Shao‐Yuan 
Published: December 2023

AbstractThe inedible parts of nuts and stone fruits are low‐cost and lignin‐rich feedstock for more sustainable production of aromatic chemicals in comparison with the agricultural and forestry residues. However, the depolymerization performances on food‐related biomass remains unclear, owing to the broad physicochemical variations from the edible parts of the fruits and plant species. In this study, the monomer production potentials of ten major fruit and nutshell biomass were investigated with comprehensive numerical information derived from instrumental analysis, such as plant cell wall chemical compositions, syringyl/guaiacyl (S/G ratios, and contents of lignin substructure linkages (β‐O‐4, β–β, β‐5). A standardized one‐pot reductive catalytic fractionation (RCF) process was applied to benchmark the monomer yields, and the results were statistically analyzed. Among all the tested biomass, mango endocarp provided the highest monolignol yields of 37.1 % per dry substrates. Positive S‐lignin (70–84 %) resulted in higher monomer yield mainly due to more cleavable β‐O‐4 linkages and less condensed C−C linkages. Strong positive relationships were identified between β‐O‐4 and S‐lignin and between β‐5 and G‐lignin. The analytical, numerical, and experimental results of this study shed lights to process design of lignin‐first biorefinery in food‐processing industries and waste management works.
High‐Quality and Wafer‐Scale Cubic Silicon Carbide Single Crystals
Authors: Wang Guobin , Sheng Da , Yang Yunfan , Li Hui , Chai Congcong , Xie Zhenkai , Wang Wenjun , Guo Jiangang , Chen Xiaolong 
Published: December 2023

Cubic silicon carbide (3C‐SiC) has superior mobility and thermal conduction over that of widely applied hexagonal 4H‐SiC. Moreover, much lower concentration of interfacial traps between insulating oxide gate and 3C‐SiC helps fabricate reliable and long‐life devices like metal‐oxide‐semiconductor field effect transistors. However, the growth of high‐quality and wafer‐scale 3C‐SiC crystals has remained a big challenge up to now despite decades‐long efforts by researchers because of its easy transformation into other polytypes during growth, limiting the development of 3C‐SiC‐based devices. Herein, we report that 3C‐SiC can be made thermodynamically favored from nucleation to growth on a 4H‐SiC substrate by top‐seeded solution growth technique, beyond what is expected by classical nucleation theory. This enables the steady growth of high‐quality and large‐size 3C‐SiC crystals (2–4‐inch in diameter and 4.0–10.0 mm in thickness) sustainable. The as‐grown 3C‐SiC crystals are free of other polytypes and have high‐crystalline quality. Our findings broaden the mechanism of hetero‐seed crystal growth and provide a feasible route to mass production of 3C‐SiC crystals, offering new opportunities to develop power electronic devices potentially with better performances than those based on 4H‐SiC.
Electrochemical cellular biosensor combined with fluorescence microscopy: An investigation of subtle changes in response of cells to a drug
Authors: Arman Seyedyousef , Tilley Richard D. , Gaus Katharina , Gooding J. Justin 
Published: December 2023

AbstractThis study presents the combination of electrochemical cell based biosensor and fluorescence microscopy on a single platform to track biomolecular processes contributing to the morphology changes of the cells. Initial experiments demonstrate that using interdigitated electrodes where the gold microfingers were comparable in width and spacing to a single cell have the optimal sensitivity in the final electrochemical cell based‐sensing device. This was determined by measuring the cell index, based on the impedance analysis of bare and cell‐covered microelectrodes. The fabrication of the electrodes on a glass substrate enabled the capture of high‐resolution fluorescence microscopy images of single cells and related intracellular calcium release inside the HeLa cells via a window incorporated into the gold microelectrode design. As an illustration of the enhanced capability of the combined approach over traditional impedance cellular assay, the opto‐electric assay was utilized as a functional readout for G protein couple receptor activation. The simultaneous examinations of cells stimulated with histamine demonstrated an association between time courses of changes in cytosolic calcium concentration and reductions in cell‐cell adhesions.
Capillary electrophoresis with capacitively coupled contactless conductivity detection (C4D) for rapid and simple determination of lactate in sweat
Authors: Rocha Kionnys N. , da Silva José A. Fracassi , de Jesus Dosil P. 
Published: December 2023

AbstractAn analytical method based on capillary electrophoresis (CE) using capacitively coupled contactless conductivity detection (C4D) was developed and validated for fast, straightforward, and reliable determination of lactate in artificial and human sweat samples. The background electrolyte was composed of equimolar concentrations (10 mmol/L) of 2‐(N‐morpholino)ethanesulfonic acid and histidine, with 0.2 mmol/L of cetyltrimethylammonium bromide as electroosmotic flow inverter. The limit of detection and quantification were 3.1 and 10.3 µmol/L, respectively. Recoveries in the 97 to 118% range were obtained using sweat samples spiked with lactate at three concentration levels, indicating an acceptable accuracy. The intraday and interday precisions were 1.49 and 7.08%, respectively. The proposed CE–C4D method can be a starting point for monitoring lactate concentrations in sweat samples for diagnostics, physiological studies, and sports performance assessment applications.
Energetic and exergetic performances of a multi‐effect desalination unit driven by a gas turbine
Authors: Cavalcanti Eduardo J. C. , Santos Erick B. A. , Carvalho Monica 
Published: December 2023

AbstractDesalination can provide additional water resources in water‐stressed zones and also in zones suffering from water pollution or insufficient/overexploited groundwater. This study carried out the energy and exergy assessments of a multi‐effect desalination unit driven by a gas turbine based on the specific exergy cost (SPECO) approach. The chemical exergies of brine and seawater are explicitly considered (most studies consider the same specific heat for input seawater and output brine). In addition, the enthalpy of each flow of the desalination unit is considered according to its salt concentration (results are then compared to the constant specific heat model). The highest exergy rates of fuel and product are obtained at the combustion chamber, and its exergy efficiency is 67.83%. The lowest exergy efficiencies were obtained at the condenser, followed by the first effect of the desalination unit, and the heat recovery steam generator. The overall exergy efficiency of the multi‐effect distillation unit is 21.49%. Regarding exergy destruction, as expected, the highest rate was obtained at the combustion chamber, which contributed with 41% to the overall exergy destruction, followed by the regenerator and heat recovery steam generator, with contributions of 16% and 11%, respectively, to overall exergy destruction.
Supercritical microalgae conversion to biofuel and value‐added components (oxygenates, hydrocarbons, and aromatics): A catalyst characterization study
Authors: Aghilinategh Maryam , Barati Mohammad , Hamadanian Masood 
Published: December 2023

AbstractThe study aimed to investigate the use of SrO/TiO2 nano‐catalysts in the one‐pot production of valuable products (such as fatty acid methyl esters, oxygenates, hydrocarbons, and aromatics) from Chlorella vulgaris microalgae through a supercritical process. The research focused on examining the impact of the factors, the SrO to TiO2 ratio, preparation method, and calcination temperature on the catalytic performance. Two calcination temperatures (600°C and 850°C), two Sr:Ti molar ratios (1 and 2), and two catalyst preparation methods (photochemical and impregnation) were considered. The catalysts were characterized using Scanning electron microscopy, transmission electron microscope, x‐ray crystallography, and Brunauer‐Emmett‐Teller techniques. The evaluation of catalyst performance primarily focused on the production of value‐added products, particularly fatty acid methyl esters (FAMEs). The results indicated that the catalyst prepared using the photochemical method with a Sr:Ti molar ratio of 2 and calcined at 850°C exhibited superior performance in terms of FAMEs and oxygenates production. It was demonstrated that the catalyst prepared using the photochemical method with higher Sr:Ti ratio had better performances in the production of biodiesel.