bluuebunny/crossref_metadata_2025_split huggingface dataset:
Understanding social risk factors of county-level disparities in COVID-19 tests per confirmed case in South Carolina using statewide electronic health records data
Authors: Shi Fanghui , Zhang Jiajia , Yang Xueying , Sun Xiaowen , Li Zhenlong , Weissman Sharon , Olatosi Bankole , Li Xiaoming 
Published: October 2023

Abstract
Background
COVID-19 testing is essential for pandemic control, and insufficient testing in areas with high disease burdens could magnify the risk of poor health outcomes. However, few area-based studies on COVID-19 testing disparities have considered the disease burden (e.g., confirmed cases). The current study aims to investigate socioeconomic drivers of geospatial disparities in COVID-19 testing relative to disease burden across 46 counties in South Carolina (SC) in the early (from April 1, 2020, to June 30, 2020) and later (from July 1, 2020, to September 30, 2021) phases of the pandemic.

Methods
Using SC statewide COVID-19 testing data, the COVID-19 testing coverage was measured by monthly COVID-19 tests per confirmed case (hereafter CTPC) in each county. We used modified Lorenz curves to describe the unequal geographic distribution of CTPC and generalized linear mixed-effects regression models to assess the association of county-level social risk factors with CTPC in two phases of the pandemic in SC.

Results
As of September 30, 2021, a total of 641,201 out of 2,941,227 tests were positive in SC. The Lorenz curve showed that county-level disparities in CTPC were less apparent in the later phase of the pandemic. Counties with a larger percentage of Black had lower CTPC during the early phase (β = -0.94, 95%CI: -1.80, -0.08), while such associations reversed in the later phase (β = 0.28, 95%CI: 0.01, 0.55). The association of some other social risk factors diminished as the pandemic evolved, such as food insecurity (β: -1.19 and -0.42; p-value is < 0.05 for both).

Conclusions
County-level disparities in CTPC and their predictors are dynamic across the pandemic. These results highlight the systematic inequalities in COVID-19 testing resources and accessibility, especially in the early stage of the pandemic. Counties with greater social vulnerability and those with fewer health care resources should be paid extra attention in the early and later phases, respectively. The current study provided empirical evidence for public health agencies to conduct more targeted community-based testing campaigns to enhance access to testing in future public health crises.
Sexual assault and vulnerability to sexually transmitted infections among homeless Brazilian women: a cross sectional qualitative study
Authors: Gonçalves Barbosa Nayara , Carvalho Mendes Lise Maria , da Costa Carbogim Fábio , Maria e Silva Angela , de Oliveira Gozzo Thaís , Gomes-Sponholz Flávia Azevedo 
Published: October 2023

Abstract
Background
Homeless women have complex life conditions and are often exposed to violence, sexual exploitation, rape, prostitution, reproductive disorders, survival sex trading, unintended pregnancies and sexually transmitted infections (STIs). The aim was to explore the existence of sexual aggression and vulnerability to STIs among homeless Brazilian women.

Methods
Fifteen interviews were conducted with homeless women who were admitted to a women’s shelter in a large city in Brazil. Data were collected through semi-structured interviews, audiorecorded and complemented with notes of the researcher in field diary, subjected to inductive thematic analysis and analyzed in light of the social relations of gender.

Results
Two themes were constructed: “Being a woman on the streets: a look at gender inequalities” and “Pain and the raped body: the scars of homeless women”. The transgression of women’s rights was observed with reports of sexual abuse interspersed with physical violence. Unprotected sexual practices were part of the daily lives of these women, with repercussions for their exposure to sexually transmitted infections. Dependence on psychoactive substances was mentioned, and transactional sex was used as a source of income to maintain such dependence, as well as to promote the women’s livelihood.

Conclusion
Homeless women experience complex situations on the streets involving exposure to different types of violence, the use of transactional sex as a survival strategy and unprotected sexual practices. Furthermore, the way in which women have been exposed to sexual assault and their coping mechanisms to those require attention. Interventions are need to improve the healthcare assistance of homeless women victims of sexual assault, considering the vulnerability of this population.
Self-care strategies for medical students: an uncontrolled mixed-methods evaluation of a mind-body-medicine group course
Authors: Scullion Raphael , Icke Katja , Tissen-Diabaté Tatjana , Adam Daniela , Ortiz Miriam , Witt Claudia M. , Brinkhaus Benno , Stöckigt Barbara 
Published: October 2023

Abstract
Background
High stress during medical education and its detrimental effects on student health is well documented. This exploratory evaluation study assesses a 10-week Mind-Body-Medicine student course, created to promote student self-care at Charité Universitätsmedizin Berlin, Germany.

Methods
During 2012–2019, uncontrolled quantitative and qualitative data were gathered from 112 student participants. Outcomes including changes in perceived stress (PSS), mindfulness (FMI/MAAS), self-reflection (GRAS), self-efficacy (GSE), empathy (SPF), and health-related quality of life (SF-12) were measured between the first (T0) and last sessions (T1). Qualitative data were obtained in focus groups at course completion and triangulated with quantitative data.

Results
Quantitative outcomes showed decreases in perceived stress and increased self-efficacy, mindfulness, self-reflection, and empathy. In focus groups, students reported greater abilities to self-regulate stressful experiences, personal growth and new insights into integrative medicine. Triangulation grounded these effects of MBM practice in its social context, creating an interdependent dynamic between experiences of self and others.

Conclusion
After completing an MBM course, students reported reduced perceived stress, increased self-efficacy, mindfulness, empathy and positive engagement with integrative concepts of doctor–patient relationships. Further research with larger randomized confirmatory studies is needed to validate these benefits.
Clinical effectiveness of supraspinatus tendon reconstruction using autogenous fascia latas for irreparable posterosuperior massive rotator cuff tears: study protocol for a randomized, controlled clinical trial
Authors: Ma Lin , Gou Xiaoli , Zhou Binghua 
Published: October 2023

Abstract
Background
Supraspinatus tendon reconstruction (STR) was recently introduced as a new treatment option for irreparable posterosuperior massive rotator cuff tears (IPMRCT). STR was thought to be more advantageous than superior capsule reconstruction (SCR) for restoring supraspinatus (SSP) dynamics. However, there has been no prospective randomized controlled study on the early clinical efficacy of STR.

Methods
A single-site, prospective, observers and patients double-blinding randomized controlled trial was designed. Fifty-eight patients aged 50–85 years with IPMRCT will be randomized 1:1 to receive either STR or SCR. The clinical outcomes were evaluated using the American Society for Shoulder and Elbow Surgery (ASES) score, range of motion (ROM), visual analogue scale (VAS) for pain, acromiohumeral distance (AHD), Goutlliar grade for fatty infiltration in the SSP, Sugaya grade for the autogenous fascia latas, isokinetic muscle strength testing and surface electromyography (EMG) testing for shoulder abduction muscle strength and complications.

Discussion
The results of this study will contribute to the treatment algorithm of IPMRCT and assist surgeons in making treatment decisions. This is the first randomized controlled trial to compare the effects of STR and SCR for the treatment of IPMRCT.

Trial registration
We registered the trial in chictr.org.cn on July 17, 2023 (register number: ChiCTR2300073716). Items from the WHO trial registry were found within the protocol.
The influence of dapagliflozin on cardiac remodeling, myocardial function and metabolomics in type 1 diabetes mellitus rats
Authors: Rodrigues Eder Anderson , Rosa Camila Moreno , Campos Dijon Henrique Salome , Damatto Felipe Cesar , Murata Gilson Masahiro , Souza Lidiane Moreira , Pagan Luana Urbano , Gatto Mariana , Brosler Jessica Yumi , Souza Hebreia Oliveira Almeida , Martins Mario Machado , Bastos Luciana Machado , Tanni Suzana Erico , Okoshi Katashi , Okoshi Marina Politi 
Published: October 2023

Abstract
Background
Sodium-glucose cotransporter (SGLT)2 inhibitors have displayed beneficial effects on the cardiovascular system in diabetes mellitus (DM) patients. As most clinical trials were performed in Type 2 DM, their effects in Type 1 DM have not been established.

Objective
To evaluate the influence of long-term treatment with SGLT2 inhibitor dapagliflozin on cardiac remodeling, myocardial function, energy metabolism, and metabolomics in rats with Type 1 DM.

Methods
Male Wistar rats were divided into groups: Control (C, n = 15); DM (n = 15); and DM treated with dapagliflozin (DM + DAPA, n = 15) for 30 weeks. DM was induced by streptozotocin. Dapagliflozin 5 mg/kg/day was added to chow. Statistical analysis: ANOVA and Tukey or Kruskal-Wallis and Dunn.

Results
DM + DAPA presented lower glycemia and higher body weight than DM. Echocardiogram showed DM with left atrium dilation and left ventricular (LV) hypertrophy, dilation, and systolic and diastolic dysfunction. In LV isolated papillary muscles, DM had reduced developed tension, +dT/dt and -dT/dt in basal condition and after inotropic stimulation. All functional changes were attenuated by dapagliflozin. Hexokinase (HK), phosphofructokinase (PFK) and pyruvate kinase (PK) activity was lower in DM than C, and PFK and PK activity higher in DM + DAPA than DM. Metabolomics revealed 21 and 5 metabolites positively regulated in DM vs. C and DM + DAPA vs. DM, respectively; 6 and 3 metabolites were negatively regulated in DM vs. C and DM + DAPA vs. DM, respectively. Five metabolites that participate in cell membrane ultrastructure were higher in DM than C. Metabolites levels of N-oleoyl glutamic acid, chlorocresol and N-oleoyl-L-serine were lower and phosphatidylethanolamine and ceramide higher in DM + DAPA than DM.

Conclusion
Long-term treatment with dapagliflozin attenuates cardiac remodeling, myocardial dysfunction, and contractile reserve impairment in Type 1 diabetic rats. The functional improvement is combined with restored pyruvate kinase and phosphofructokinase activity and attenuated metabolomics changes.
Metabolic regulation of microglial phagocytosis: Implications for Alzheimer's disease therapeutics
Authors: Lepiarz-Raba Izabela , Gbadamosi Ismail , Florea Roberta , Paolicelli Rosa Chiara , Jawaid Ali 
Published: October 2023

AbstractMicroglia, the resident immune cells of the brain, are increasingly implicated in the regulation of brain health and disease. Microglia perform multiple functions in the central nervous system, including surveillance, phagocytosis and release of a variety of soluble factors. Importantly, a majority of their functions are closely related to changes in their metabolism. This natural inter-dependency between core microglial properties and metabolism offers a unique opportunity to modulate microglial activities via nutritional or metabolic interventions. In this review, we examine the existing scientific literature to synthesize the hypothesis that microglial phagocytosis of amyloid beta (Aβ) aggregates in Alzheimer’s disease (AD) can be selectively enhanced via metabolic interventions. We first review the basics of microglial metabolism and the effects of common metabolites, such as glucose, lipids, ketone bodies, glutamine, pyruvate and lactate, on microglial inflammatory and phagocytic properties. Next, we examine the evidence for dysregulation of microglial metabolism in AD. This is followed by a review of in vivo studies on metabolic manipulation of microglial functions to ascertain their therapeutic potential in AD. Finally, we discuss the effects of metabolic factors on microglial phagocytosis of healthy synapses, a pathological process that also contributes to the progression of AD. We conclude by enlisting the current challenges that need to be addressed before strategies to harness microglial phagocytosis to clear pathological protein deposits in AD and other neurodegenerative disorders can be widely adopted.
Social media usage and students’ social anxiety, loneliness and well-being: does digital mindfulness-based intervention effectively work?
Authors: Sun Li 
Published: October 2023

Abstract
Background
The increasing integration of digital technologies into daily life has spurred a growing body of research in the field of digital psychology. This research has shed light on the potential benefits and drawbacks of digital technologies for mental health and well-being. However, the intricate relationship between technology and psychology remains largely unexplored.

Purpose
This study aimed to investigate the impact of mindfulness-based mobile apps on university students' anxiety, loneliness, and well-being. Additionally, it sought to explore participants' perceptions of the addictiveness of these apps.

Method
The research utilized a multi-phase approach, encompassing a correlational research method, a pretest–posttest randomized controlled trial, and a qualitative case study. Participants were segmented into three subsets: correlations (n = 300), treatment (n = 60), and qualitative (n = 20). Data were gathered from various sources, including the social anxiety scale, well-being scale, social media use integration scale, and an interview checklist. Quantitative data was analyzed using Pearson correlation, multiple regression, and t-tests, while qualitative data underwent thematic analysis.

Results
The study uncovered a significant correlation between social media use and the variables under investigation. Moreover, the treatment involving mindfulness-based mobile apps led to a reduction in students' anxiety and an enhancement of their well-being. Notably, participants held various positive perceptions regarding the use of these apps.

Implications
The findings of this research hold both theoretical and practical significance for the field of digital psychology. They provide insight into the potential of mindfulness-based mobile apps to positively impact university students' mental health and well-being. Additionally, the study underscores the need for further exploration of the intricate dynamics between technology and psychology in an increasingly digital world.
Social anxiety and celebrity worship: the mediating effects of mobile phone dependence and moderating effects of family socioeconomic status
Authors: Jia Rong , Yang Qing , Liu Bo , Song Han , Wang Zhengjun 
Published: October 2023

AbstractThe Absorption-addiction model suggests that people worship celebrities to compensate for some personal or social defects, so poor mental state is related to celebrity worship. The current study aimed to explore the underlying mechanisms influencing celebrity worship. A total of 1,147 participants (aged 19–26 years) completed online questionnaires to assess social anxiety, mobile phone dependence, parental income and celebrity worship. Results showed that: (1) social anxiety, socioeconomic status (SES) and celebrity worship were positively correlated; (2) Social anxiety affected celebrity worship through mobile phone dependence; (3) SES played a moderating role in the mediation model. At higher levels of SES, individuals with high social anxiety showed reduced dependence on mobile phones. These findings highlight the importance of mobile phone dependence and family SES in celebrity worship. Additionally, the findings demonstrated that females are more likely to pay attention to celebrities, but the greater SES and reduced mobile phone dependence can mitigate their celebrity addiction.
Integration of distributed acoustic sensing for real-time seismic monitoring of a geothermal field
Authors: Azzola Jérôme , Thiemann Katja , Gaucher Emmanuel 
Published: October 2023

AbstractTo accelerate the energy transition, the exploitation of deep geothermal reservoirs is becoming a priority to supply district heating networks in areas with high potential for geothermal applications. However, the sustainable development of the resource exploitation implies minimizing the associated risks, in particular related to induced seismicity, while optimizing operational processes. Besides, the growth of this energy sector, often supported by financial aid programs, provides resources to the industry that were not available in the past to implement advanced monitoring strategies. In this context, we present a monitoring system establishing Distributed Acoustic Sensing (DAS) as an effective component of the seismic network used for the monitoring of the geothermal field of Schäftlarnstraße (Munich, Germany). We also investigate its potential for real-time seismic monitoring in an urban environment and for risk mitigation. The monitoring system is based on a data management system linking the on-site acquisition infrastructure, including the fiber optic cable deployed in an injection well and the associated DAS interrogator, to a cloud Internet-of-Things (IoT) platform. The latter is designed to deliver both a secure storage environment for the DAS recordings and optimized computing resources for their processing. The proposed solution has been tested over a six-month period under operating conditions of the geothermal field. The survey proves the feasibility of efficiently acquiring and processing the large flow of continuous DAS data. The processing outcomes, emphasized by two detected local seismic events, demonstrate the suitability of DAS, cemented behind the casing of a flowing well, for (micro-) seismic monitoring of the geothermal site. The processing applied to the data takes advantage of the high spatial density of the acquisitions for their de-noising and for the detection of events. We find that the DAS monitoring system is capable of successfully detecting an event that could not be detected by the standard surface or shallow-borehole 3C-seismometers, despite noisy conditions associated with the urban environment and the field operation. The six-month test period demonstrates the potential of DAS to be integrated as a routine seismic monitoring component of an operating geothermal field. In addition, it highlights its advantageous role as a complement to surface seismometer-based networks, particularly in urban environments.
Challenges in reaching patients with severe mental illness for trials in general practice—a convergent mixed methods study based on the SOFIA pilot trial
Authors: Tranberg Katrine , Due Tina Drud , Rozing Maarten , Jønsson Alexandra Brandt Ryborg , Kousgaard Marius Brostrøm , Møller Anne 
Published: October 2023

Abstract
Background
Patients with severe mental illness (SMI) die prematurely due to undetected and inadequate treatment of somatic illnesses. The SOFIA pilot study was initiated to mend this gap in health inequity. However, reaching patients with SMI for intervention research has previously proven difficult. This study aimed to investigate the recruitment of patients with SMI for the SOFIA pilot study in 2021.

Methods
We used a mixed-method convergent design. The qualitative material comprised 20 interviews with general practitioners (GPs) and staff, during patient recruitment. The quantitative data consisted of process data on baseline characteristics, GPs reported reasons for excluding a patient, reported reasons for patients declining participation, and registered data from a Danish population of patients with SMI. We used thematic analysis in the qualitative analysis and descriptive statistics for the quantitative analysis. Pillar integration was used for integrating the material.

Results
Our findings show that selection bias occurred in the pilot study. We describe four main themes based on the integrated analysis that highlights selection issues: (1) poor data quality and inconsistency in defining severity definitions troubled identification and verification, (2) protecting the patient and maintaining practice efficiency, (3) being familiar with the patient was important for a successful recruitment, and (4) in hindsight, the GPs questioned whether the target population was reached.

Conclusions
In the light of theories of professions and street-level bureaucracy, we find that the main drivers of the patient selection bias occurring in the SOFIA pilot study were that 1) GPs and staff mended eligibility criteria to protect certain patients and/or to minimize workload and maintain efficiency in the practice 2) the data from the GP record systems and the digital assessment tool to assist recruitment was not optimal. Interventions targeting this patient group should carefully consider the recruitment strategy with a particular focus on professionals’ discretionary practices and information technology pitfalls.

Trial registration
The pilot trial protocol was registered on the 5th of November 2020. The registration number is NCT04618250.
Group-based PFMT programme for preventing and/or treating UI in pregnant women: protocol of a randomized controlled feasibility study
Authors: Yang Xiaowei , Zhang Aixia , Zhu Rong , Sayer Lynn , Bassett Sam , Woodward Sue 
Published: October 2023

Abstract
Background
Urinary incontinence (UI) is a prevalent health problem in women worldwide. Many women experience UI during pregnancy. The National Institute for Health and Care Excellence (NICE) recommended pelvic floor muscle training (PFMT) as the first-line conservative treatment for UI. However, it is not widely implemented due to the limited number of healthcare trainers. Group-based PFMT has been used with older women and a limited number of maternity studies. But the effectiveness of the group-based PFMT needs to be investigated because the overall quality of the studies is low. Therefore, this study aims to assess the feasibility of delivering a group-based PFMT programme for pregnant women in Nanjing city.

Methods
This feasibility study will be conducted in Nanjing Maternity and Child Health Care Hospital in China, using a mixed methods design to investigate the feasibility and acceptability of delivering group-based PFMT to pregnant women. Pregnant women with or without the symptoms of UI will be included. This study aims to recruit 48 pregnant women with 24 in each arm. Participants will receive either the group-based PFMT delivered by a midwife or usual antenatal care which includes only verbal instruction on PFMT. The study will assess the completion rates, acceptability of outcome measures, recruitment and retention rate and calculate an appropriate sample size for a future study.

Discussion
The results of this study will inform the design and implementation of a definitive randomized clinical trial to explore the effectiveness of the intervention.

Trial registration
ClinicalTrials.gov, NCT05242809.
Some properties for meromorphic functions associated with integral operators
Authors: Kota W. Y. , El-Ashwah R. M. 
Published: October 2023

AbstractIn the present paper we aim at proving some subordinations properties for meromorphic functions analytic in the punctured unit disc $$\Delta ^*=\{z:0<|z|<1\}$$

Δ
∗

=

{
z
:
0
<
|
z
|
<
1
}

with a simple pole at the origin. The functions under investigation are associated with two integral operators $$\mathcal {P}_\sigma ^\gamma$$

P
σ
γ

and $$\mathcal {Q}_\sigma ^\gamma$$

Q
σ
γ

(see Lashin in Comput Math Appl 59:524–531, 2010, https://doi.org/10.1016/j.camwa.2009.06.015). Several other results and numerical examples are also obtained.