bluuebunny/crossref_metadata_2025_split huggingface dataset:
Blood salvage and autotransfusion during orthotopic liver transplantation for hepatocellular carcinoma: A systematic review and meta‐analysis
Authors: Hinojosa‐Gonzalez David E. , Salgado‐Garza Gustavo , Tellez‐Garcia Eduardo , Escarcega‐Bordagaray Jaime A. , Bueno‐Gutierrez Luis Carlos , Madrazo‐Aguirre Katheryne , Muñoz‐Hibert Monica I. , Diaz‐Garza Karla G. , Ramirez‐Mulhern Isabela , Alvarez de la Reguera‐Babb Rodrigo , Flores‐Villalba Eduardo , Rodarte‐Shade Mario , Gonzalez‐Urquijo Mauricio 
Published: December 2023

AbstractBackground:Hepatocellular carcinoma (HCC) is a significant cause of oncologic mortality worldwide. Liver transplantation represents a curative option for patients with significant liver dysfunction and absence of metastases. However, this therapeutic option is associated with significant blood loss and frequently requires various transfusions and intraoperative blood salvage for autotransfusion (IBS‐AT) with or without a leukocyte reduction filter. This study aimed to analyze available evidence on long‐term oncologic outcomes of patients undergoing liver transplantation for HCC with and without IBS‐AT.Methods:Per PRISMA guidelines, a systematic review of keywords “Blood Salvage,” “Auto‐transfusion,” “Hepatocellular carcinoma,” and “Liver‐transplant” was conducted in PubMed, EMBASE, and SCOPUS. Studies comparing operative and postoperative outcomes were screened and analyzed for review.Results:Twelve studies totaling 1704 participants were included for analysis. Length of stay, recurrence rates, and overall survival were not different between IBS‐AT group and non IBS‐AT group.Conclusion:IBS‐AT use is not associated with increased risk of recurrence in liver transplant for HCC even without leukocyte filtration. Both operative and postoperative outcomes are similar between groups. Comparison of analyzed studies suggest that IBS‐AT is safe for use during liver transplant for HCC.
Recurrent papulonodular herpes zoster, with syringitis, folliculitis, and vasculitis as clues to the diagnosis
Authors: Fawzy Marwa Mohamed , El‐Enany Galal , Abdelraouf Salma M. A. , Abdelkader Heba Ahmed 
Published: December 2023

AbstractHerpes zoster (HZ) may have atypical clinical presentations, particularly in immunosuppressed patients. Nodular HZ is an extremely rare condition. We report the first case of recurrent papulonodular HZ in an adult patient with inflammatory bowel disease (IBD) receiving biologic treatment. More interestingly, there was no epidermal involvement on histopathological examination, but the involvement of the adnexa and blood vessels was a clue to the diagnosis in view of the clinical context. We wish to raise awareness of this rare manifestation of HZ for early diagnosis and proper treatment.
Evaluation der Hautkrebsfrüherkennung in Deutschland mit Krebsregisterdaten – Herausforderungen, Lösungen und aktuelle Trends
Authors: Hübner Joachim , Baltus Hannah , Eisemann Nora , Rohr Maren , Schumann Laura , Augustin Jobst , Hagenström Kristina , Wolf Sandra , Garbe Claudia , Augustin Matthias , Katalinic Alexander 
Published: December 2023

ZusammenfassungHintergrund und ZieleDie Evidenz für einen Nutzen des 2008 in Deutschland eingeführten Hautkrebsscreenings ist schwach. Wir untersuchen, inwieweit Daten der deutschen epidemiologischen Krebsregister geeignet sind zur Evaluation des Hautkrebsscreenings beizutragen, und berichten diese Evaluationsergebnisse.Material und MethodikDie Hautkrebsdaten der Krebsregister aus den Jahren 1999–2019 wurden hinsichtlich Vollzähligkeit und Vollständigkeit beschrieben. Regionale Datenpools unterschiedlicher Validität wurden definiert, fehlende Daten sofern sinnvoll mehrfach imputiert und zeitliche Trends analysiert. Ergänzend wurden Daten der Todesursachenstatistik herangezogen.ErgebnisseBelastbare Vollzähligkeitsschätzungen liegen nur für das maligne Melanom (ICD‐10: C43) vor. Auf Basis eines regionalen Datenpools, der circa 21% der deutschen Bevölkerung abdeckt, kann das melanombezogene Krankheitsgeschehen seit 2005 valide beschrieben werden. Für T‐Stadium und Lokalisation liegen ausreichend Informationen für eine multiple Imputation vor. Die Trendanalysen zeigen im zeitlichen Zusammenhang mit der Einführung der Früherkennung kurzfristig erwartbare Inzidenzänderungen, die in eine langanhaltende hohe Inzidenz übergehen. Die Rate fortgeschrittener Stadien geht nicht wesentlich zurück. Ab 2014 sinkt die bis dahin steigende Melanommortalität.SchlussfolgerungenAdäquat ausgewählte und aufbereitete Krebsregisterdaten eignen sich zur bevölkerungsbezogenen Bewertung des Hautkrebsscreenings. Eine Erklärung des anhaltend hohen Inzidenzniveaus gelingt auf Basis der Krebsregisterdaten nicht. In Betracht kommen insbesondere Überdiagnosen oder ein Anstieg der Hintergrundinzidenz. Der Nutzen des Hautkrebsscreenings bleibt offen.
Prospective cross‐organ analysis for the causes of fever and increased inflammatory response after endoscopic resection
Authors: Mizutani Mari , Minesaki Daisuke , Morioka Kohei , Iwata Kentaro , Miyazaki Kurato , Masunaga Teppei , Kubosawa Yoko , Hayashi Yukie , Sasaki Motoki , Akimoto Teppei , Takatori Yusaku , Matsuura Noriko , Nakayama Atsushi , Sujino Tomohisa , Takabayashi Kaoru , Kanai Takanori , Yahagi Naohisa , Kato Motohiko 
Published: December 2023

ObjectivesFever and increased inflammatory responses sometimes occur following endoscopic resection (ER). However, the differences in causes according to the organ are scarcely understood, and several modified ER techniques have been proposed. Therefore, we conducted a comprehensive prospective study to investigate the cause of fever and increased inflammatory response across multiple organs after ER.MethodsWe included patients who underwent gastrointestinal endoscopic submucosal dissection (ESD) and duodenal endoscopic mucosal resection at our hospital between January 2020 and April 2022. Primary endpoints were fever and increased C‐reactive protein (CRP) levels following ER. The secondary endpoints were risk factors for aspiration pneumonia. Blood tests and radiography were performed on the day after ER, and computed tomography was performed if the cause was unknown.ResultsAmong the 822 patients included, aspiration pneumonia was the most common cause of fever and increased CRP levels after ER of the upper gastrointestinal tract (esophagus, 53%; stomach, 48%; and duodenum, 71%). Post‐ER coagulation syndrome was most common after colorectal ESD (38%). On multivariate logistic regression analysis, lesions located in the esophagus (odds ratio [OR] 3.57; P < 0.001) and an amount of irrigation liquid of ≥1 L (OR 3.71; P = 0.003) were independent risk factors for aspiration pneumonia.ConclusionsAspiration pneumonia was the most common cause of fever after upper gastrointestinal ER and post‐ER coagulation syndrome following colorectal ESD. Lesions in the esophagus and an amount of irrigation liquid of ≥1 L were independent risk factors for aspiration pneumonia.
Effects of CASZ1, WNT2B and PTPRG SNPs on stroke susceptibility in the Chinese Han population
Authors: Zhang Huan , Chang Yanting , Li Yujie , Wei Jie , Ma Xiaoya , Zhou Wenqian , Zang Xufeng , Jin Tianbo , Wu Songdi 
Published: December 2023

AbstractBackgroundStroke is an important cause of death and disability worldwide, ranking second in the cause of death, and it is thought to be related to genetic factors. The purpose of our study is to investigate the association between CASZ1, WNT2B and PTPRG single nucleotide polymorphisms (SNPs) and stroke risk in the Chinese population.MethodsWe recruited 1418 volunteers, comprised of 710 stroke cases and 708 controls in this study. We used MassARRAY iPLEX GOLD method to genotype the three SNPs on CASZ1, WNT2B and PTPRG. Logistic regression was used to analyse the association between these SNPs and stroke, and odds ratios (ORs) and 95% confidence intervals (CIs) were then calculated. What's more, the interactions among SNPs were predicted by multi‐factor dimensionality reduction (MDR) analysis.ResultsThis research demonstrated that CASZ1 rs880315 and PTPRG rs704341 were associated with reduced stroke susceptibility. More precisely, CASZ1 rs880315 was associated with reduced stroke susceptibility in people aged ≤64 years and women. PTPRG rs704341 was associated with reduced stroke susceptibility in people aged >64 years, women, non‐smokers and non‐drinkers. Conversely, WNT2B rs12037987 was related to elevated stroke susceptibility in people aged >64 years, women and non‐smokers. In addition, CASZ1 rs880315, WNT2B rs12037987 and PTPRG rs704341 had a strong redundancy relationship.ConclusionOur study concludes that CASZ1 rs880315, WNT2B rs12037987 and PTPRG rs704341 are associated with stroke, and the study provides a basis for assessing genetic variants associated with stroke risk in the Han Chinese population.
Interactive effects of total dissolved gas supersaturation and suspended sediment on the swimming abilities of two fish species
Authors: Zhang Qiyu , Liu Xiaoqing , Shi Haoran , Yang Yao 
Published: December 2023

AbstractDischarged floods containing a large amount of suspended sediment (SS) can lead to total dissolved gas (TDG) supersaturation downstream of dams. The swimming ability of fish may be affected by TDG supersaturation and excessive SS. However, previous studies focused only on the separate effects of TDG and SS, ignoring their combined effects. In this study, juvenile rock carp and grass carp were selected to assess the interactive effects of TDG and SS on fish swimming ability. A totally crossed two‐factorial design (six TDG levels: 100%, 115%, 120%, 125%, 130% and 135%; four SS concentrations: 0, 50, 100 and 150 mg/L) was set, and the critical swimming speed (Ucrit) and the burst swimming speed (Uburst) were measured. The findings indicated that the swimming abilities (Ucrit and Uburst) of both fish species decreased with increasing TDG levels and SS concentrations. Separate exposure to TDG significantly decreased the swimming abilities of the two fish species, whereas separate exposure to SS decreased only the swimming abilities of juvenile grass carp. Juvenile rock carp exhibited weaker swimming abilities than juvenile grass carp in TDG‐supersaturated water. Additionally, the interaction between TDG and SS reduced the swimming abilities of juvenile rock carp and grass carp compared with a separate effect, but this reduction was significant only for the Ucrit of juvenile grass carp. This study demonstrates that TDG‐supersaturated water containing SS during flooding may result in fish failure through fishways.
In the shadows of gratitude: On mooded spaces of vulnerability and care
Authors: Danely Jason 
Published: December 2023

AbstractGratitude is a ubiquitous phenomenon in everyday social interactions, yet it has received relatively little attention within anthropology. Past approaches to gratitude have focused on its practical expressions within exchange relationships. In contrast, this article considers the phenomenology of gratitude as a moral mood. Drawing on ethnographic episodes of gratitude between older care‐recipients and their unpaid family carers in Japan, I argue that gratitude generates an aesthetic atmosphere that attunes carer and cared‐for to each other. I explore this through the Japanese notion “kage,” or the “shadow,” an atmosphere of shared interdependence and vulnerability that is not reducible to darkness or light, pain, or comfort. In the context of informal care of older people, this ambiguity provides space for sharing complex relational experiences and easing the weight of emotional strain. This Japanese example provides a model of new ways to engage with gratitude ethnographically, particularly in situations involving close care.
Fossilized giant sulfide‐oxidizing bacteria from the Devonian Hollard Mound seep deposit, Morocco
Authors: Smrzka Daniel , Zwicker Jennifer , Schulz‐Vogt Heide , Little Crispin T. S. , Rieder Max , Meister Patrick , Gier Susanne , Peckmann Jörn 
Published: December 2023

AbstractThe giant sulfide‐oxidizing bacteria are particularly prone to preservation in the rock record, and their fossils have been identified in ancient phosphorites, cherts, and carbonates. This study reports putative spherical fossils preserved in the Devonian Hollard Mound hydrocarbon‐seep deposit. Based on petrographical, mineralogical, and geochemical evidence the putative microfossils are interpreted as sulfide‐oxidizing bacteria similar to the present‐day genus Thiomargarita, which is also found at modern hydrocarbon seeps. The morphology, distribution, size, and occurrence of the fossilized cells show a large degree of similarity to their modern counterparts. Some of the spherical fossils adhere to worm tubes analogous to the occurrence of modern Thiomargarita on the tubes of seep‐dwelling siboglinid worms. Fluorapatite crystals were identified within the fossilized cell walls, suggesting the intercellular storage of phosphorus analogous to modern Thiomargarita cells. The preservation of large sulfide‐oxidizing bacteria was probably linked to changing biogeochemical processes at the Hollard Mound seep or, alternatively, may have been favored by the sulfide‐oxidizing bacteria performing nitrate‐dependent sulfide oxidation—a process known to induce carbonate precipitation. The presence of sulfide‐oxidizing bacteria at a Devonian hydrocarbon seep highlights the similarities of past and present chemosynthesis‐based ecosystems and provides valuable insight into the antiquity of biogeochemical processes and element cycling at Phanerozoic seeps.
Divergent ecological responses to typhoon disturbance revealed via landscape‐scale acoustic monitoring
Authors: Ross Samuel R. P.‐J. , Friedman Nicholas R. , Dudley Kenneth L. , Yoshida Takuma , Yoshimura Masashi , Economo Evan P. , Armitage David W. , Donohue Ian 
Published: December 2023

AbstractClimate change is increasing the frequency, intensity, and duration of extreme weather events across the globe. Understanding the capacity for ecological communities to withstand and recover from such events is critical. Typhoons are extreme weather events that are expected to broadly homogenize ecological dynamics through structural damage to vegetation and longer‐term effects of salinization. Given their unpredictable nature, monitoring ecological responses to typhoons is challenging, particularly for mobile animals such as birds. Here, we report spatially variable ecological responses to typhoons across terrestrial landscapes. Using a high temporal resolution passive acoustic monitoring network across 24 sites on the subtropical island of Okinawa, Japan, we found that typhoons elicit divergent ecological responses among Okinawa's diverse terrestrial habitats, as indicated by increased spatial variability of biological sound production (biophony) and individual species detections. This suggests that soniferous communities are capable of a diversity of different responses to typhoons. That is, spatial insurance effects among local ecological communities provide resilience to typhoons at the landscape scale. Even though site‐level typhoon impacts on soundscapes and bird detections were not particularly strong, monitoring at scale with high temporal resolution across a broad spatial extent nevertheless enabled detection of spatial heterogeneity in typhoon responses. Further, species‐level responses mirrored those of acoustic indices, underscoring the utility of such indices for revealing insight into fundamental questions concerning disturbance and stability. Our findings demonstrate the significant potential of landscape‐scale acoustic sensor networks to capture the understudied ecological impacts of unpredictable extreme weather events.
High phenotypic variation found within the offspring of each mother tree in Fagus sylvatica regardless of the environment or source population
Authors: Schmeddes Jonas , Muffler Lena , Barbeta Adrià , Beil Ilka , Bolte Andreas , Holm Stefanie , Karitter Pascal , Klisz Marcin , Löf Magnus , Nicolas Manuel , Peñuelas Josep , Vitasse Yann , Weigel Robert , Kreyling Juergen 
Published: December 2023

AbstractAimClimate change challenges temperate forest trees by increasingly irregular precipitation and rising temperatures. Due to long generation cycles, trees cannot quickly adapt genetically. Hence, the persistence of tree populations in the face of ongoing climate change depends largely on phenotypic variation, that is the capability of a genotype to express variable phenotypes under different environmental conditions, known as plasticity. We aimed to quantify phenotypic variation of central Europe's naturally dominant forest tree across various intraspecific scales (individuals, mother trees (families), populations) to evaluate its potential to respond to changing climatic conditions.LocationEurope.Time Period2016–2019.Major Taxa StudiedEuropean beech (Fagus sylvatica L.).MethodsWe conducted a fully reciprocal transplantation experiment with more than 9000 beech seeds from seven populations across a Europe‐wide gradient. We compared morphological (Specific Leaf Area), phenological (leaf unfolding) and fitness‐related (growth, survival) traits across various biological scales: within single mother trees, within populations and across different populations under the contrasting climates of the translocation sites.ResultsThe experiment revealed significant phenotypic variation within the offspring of each mother tree, regardless of geographic origin. Initially, seedling height growth varied among mother trees and populations, likely due to maternal effects. However, the growth performance successively aligned after the first year. In summary, we observed a consistent growth response in different beech populations to diverse environments after initial maternal effects.Main ConclusionsThe study strikingly demonstrates the importance of considering intraspecific variation. Given the surprisingly broad spectrum of phenotypes each mother tree holds within its juvenile offspring, we conclude that Fagus sylvatica might have the potential for medium‐term population persistence in face of climate change, provided that this pattern persists into later life stages. Hence, we also suggest further investigating the inclusion of passive adaptation and natural dynamics in the adaptive management of forests.
Women on the move for science, technology, engineering and mathematics: Gender selectivity in higher education student migration
Authors: Narh Ebenezer D. , Buzzelli Michael 
Published: December 2023

AbstractDespite the gendered rebalancing of enrolments in higher education (HE) in the West, the underrepresentation of women in science, technology, engineering and mathematics (STEM) disciplines persists. Gendered selectivity of field of study influences higher education student migration (HESM) and in turn sheds light on HE participation. Framed by gender intersectionality theories both in HE studies and migration scholarship, this paper uses innovative data to analyse the intersectional effect of gender and field of study on HESM in Canada. Based on Statistics Canada's postsecondary student information system for the 2019/20 academic year, Canadian interregional flow matrixes structured by gender, field and level of study are constructed and analysed. The results show compelling evidence of the influence of gendered differences in HESM when intersected with field and level of study. Notably, women pursuing STEM studies migrate significantly more than any other grouping (i.e. gender, field and level of study groupings). The paper concludes with a discussion of policy implications for the influence of HESM on community demographic make‐up and local labour markets, as well as future research including the need to understand gendered dimensions of migration intentions and motivations.
Thermally matched chalcogenide glasses with high refractive index contrast for infrared graded‐index lenses
Authors: Chen Qian , Yang Anping , Ma Cheng , Yang Zhijie , Liu Zijun , Shen Xiang , Yang Zhiyong 
Published: December 2023

AbstractInfrared graded‐index (GRIN) lenses are desirable for realizing miniaturization and lightweight of infrared imaging systems. Chalcogenide glasses have excellent infrared transparency, good rheological property, and large refractive index range, making them preferred materials for infrared GRIN lenses. In this work, aiming to find thermally matched chalcogenide compositions with high refractive index contrast for preparing GRIN glasses by the stacking diffusion approach, we investigated characteristic temperature, thermal expansion coefficient and refractive index of Ge‐As‐Se and Ge‐As‐Se‐Te glasses, optimized the glass compositions, and evaluated the feasibility of preparing GRIN glass using the optimized chalcogenide glass powders. It is found that Ge20As20Se20Te40 and Ge12As22Se66 glasses have similar softening temperature (247°C vs. 249°C), reasonably difference of thermal expansion coefficient (3.8 ppm/K), and large refractive index contrast (∼.48). The glass powders with composition xGe20As20Se20Te40‐(1‐x) Ge12As22Se66 can be hot‐pressed into glass disks with good transmittance at the same temperature and pressure. Graded refractive index profile is formed near the interface between the layers after the co‐pressed glass is thermally treated. These results demonstrate the prospect of the compositions for preparing infrared GRIN glasses.
Food insecurity in adults with severe mental illness living in Northern England: Peer research interview findings
Authors: Giles Emma L. , Eskandari Fatemeh , McGeechan Grant , Scott Steph , Lake Amelia A. , Teasdale Scott , Ekers David , Augustine Alex , Le Savauge Nikita , Lynch Chris , Moore Hannah , Smith Jo 
Published: December 2023

AbstractFood insecurity means that a person does not have access to sufficient nutritious food for normal growth and health. Food insecurity can lead to many health problems such as obesity, heart disease, diabetes, and other long term health conditions. People living with a severe mental illness are more likely to experience food insecurity than people without mental illness. Peer‐led in‐depth interviews were conducted with adults with severe mental illness from Northern England, during which their experiences of food insecurity and strategies to tackle food insecurity were discussed. Interviews took place between March and December 2022, with interviews being transcribed and analysed using deductive and inductive thematic analysis. Thirteen interviews were conducted, finding that food insecurity in adults with severe mental illness was often a long‐standing issue. Unemployment, the cost‐of‐living crisis and fuel poverty impacted on experiences of food insecurity. Difficulties accessing food banks such as transport, stigma, and the limited selection of available food was also discussed. Strategies to tackle food insecurity centred on making food banks more accessible and improving the quality of available food. Future research should aim to eradicate food insecurity for adults with severe mental illness, as limited research and action focuses on this population group over and above ‘mental illness’ or ‘poor mental health’. Removing barriers to accessing food such as lack of transport, and providing food which is of adequate nutritional quality, should be prioritised, as well as tackling the stigma and accessibility issues surrounding food banks use.