bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lifetime risk of severe kidney disease in lithium-treated patients: a retrospective study
Authors: Golic Mihaela , Aiff Harald , Attman Per-Ola , Ramsauer Bernd , Schön Staffan , Steingrimsson Steinn , Svedlund Jan 
Published: December 2023

Abstract
Background
Lithium is an essential psychopharmaceutical, yet side effects and concerns about severe renal function impairment limit its usage.

Aims
Our objectives were to quantify the occurrence of chronic kidney disease stage 4 or higher (CKD4 +) within a lithium-treated population, using age- and time-specific cumulative incidence and age-specific lifetime risk as measures of disease occurrence. Additionally, we aimed to investigate the association between the duration of lithium treatment and the risk of CKD4 + .

Methods
We identified patients from the Sahlgrenska University Hospital’s laboratory database. We conducted a retrospective cohort study employing cumulative incidence functions that account for competing deaths to estimate cumulative and lifetime risk of CKD4 + . A subdistribution hazards model was employed to explore baseline covariates. For measuring the association between the duration of lithium treatment and CKD4 + occurrence, we used a matched 1:4 case–control study design and logistic regression.

Results
Considering a 90-year lifetime horizon, the lifetime risk of CKD4 + for patients initiating lithium treatment between ages 55 and 74 ranged from 13.9% to 18.6%. In contrast, the oldest patient group, those starting lithium at 75 years or older, had a lower lifetime risk of 5.4%. The 10-year cumulative risk for patients starting lithium between ages 18 and 54 was minimal, ranging from 0% to 0.7%. Pre-treatment creatinine level was a predictive factor, with a hazard ratio of 4.6 (95% CI 2.75–7.68) for values within the upper third of the reference range compared to the lower third. Moreover, twenty or more years of lithium exposure showed a strong association with an increased risk of CKD4 + compared to 1–5 years of lithium use, with an odds ratio of 6.14 (95% CI 2.65–14.26).

Conclusions
The risk of CKD4 + among lithium-treated patients exhibited significant age-related differences. Patients under 55 years old had negligible 10-year risk, while the lifetime risk for those aged 75 and older was limited. Duration of lithium treatment, especially exceeding 20 years, emerged as a significant risk factor. For individual risk assessment and prediction, consideration of age, pre-treatment creatinine levels, and the chosen time horizon for prediction is essential.
Cognition in soccer and futsal: evidence of validity of a 4-instrument protocol to assess executive functioning among women athletes
Authors: Filgueiras Alberto , Stults-Kolehmainen Matthew , Melo Gislane , Keegan Richard 
Published: December 2023

AbstractEvidence suggests that success in sports, especially soccer and futsal are linked to higher levels of executive functioning. Still, the literature does not present a homogeneous set of instruments to measure executive functions, which leads to large variability in results. In this paper, we assembled four already recognised measures to propose a valid 4-instrument protocol to assess executive functions among soccer and futsal athletes. We conducted two studies to validate the proposed protocol. We addressed known-groups validity and latent structure in Study 1 for data collected on 105 female soccer and futsal athletes from elite and lower-division clubs. Findings pointed to partial validity of the protocol - with working memory and inhibition showing the best results. For Study 2, we used performance data from 51 elite female soccer players collected throughout a season of the first division league to assess predictive validity. Our protocol was able to partially replicate previous findings and added new insights on how working memory, processing speed and higher-level executive functions might play different roles for goalscoring and assist-making skills. Specifically, study 1 did not find a significant difference between elite and lower-division athletes in higher-order executive functions as in previous studies, but it did find on visual working memory and inhibitory control which weights towards higher demands of core executive functions. On the other hand, study 2 yielded significant results for processing speed and visual working memory to predict assists among elite soccer players, but not inhibitory control as previous findings suggested. Regardless, the proposed 4-instrument protocol showed adequate criterion and structural validity in both studies.
Cross-Cultural Adaptation of the CRS-PRO Questionnaire into French
Authors: Fieux Maxime , Carsuzaa Florent , Charriot Jeremy , Michel Justin , Subtil Fabien , Sowerby Leigh J. , Radulesco Thomas , Favier Valentin 
Published: December 2023

Background Chronic rhinosinusitis (CRS), encompasses many different clinical patterns with variable response to treatment. Precise criteria specifying disease severity and control are lacking in the current literature. Our aim was to perform a cross-cultural adaptation of the CRS-PRO, creating a French version for use as a routine questionnaire in the assessment of patients with CRS. Methods The CRS-PRO questionnaire was translated according to the recommendations of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR) through a three-step procedure including a backward translation. Results Seven of 12 items were initially discordant between the three translators before achieving consensus (Step 1). Two of 12 items were discordant between the backward translation and the initial CRS-PRO version regarding the word “mucus”(Step 2). Step 3 allowed the creation of a French proof-read version of the CRS-PRO questionnaire. Thirty patients were included for initial validation, mean age of 49.2 ± 15 years and 63.3% (19/30) male. It took them 67 ± 23 s to complete the questionnaire without any patients requiring more than 2 min. Conclusion This study presents the French version of the CRS-PRO questionnaire—an adapted, validated, and well-accepted instrument to evaluate the CRS symptoms in the French speaking population.
Exploring the role of social determinants in the risk reduction of landslide-prone settlements: a case study of Giripurno Village in Central Java, Indonesia
Authors: Purwitaningsih Santika , Nhindyasari Pramasti Dyah , Sambodo Ahmad Priyo , Santosa Amadeo Benvenuto , Hilal Atina Salsabila , Wulandari Ayu , Fitriyah S. Aisyah Azka Nurul , Wijaya Ryan Andri , Asano Junichiro , Sartohadi Junun , Setiawan Muhammad Anggri , Sulaiman Muhammad , Pratiwi Elok Surya 
Published: December 2023

Abstract
Background
The world population is still growing. The growing population caused a changes in the trend of selecting settlements location. Due to the limited flat land, people were starting to form settlements in a hilly or mountainous area which is prone to landslide. The community used to move from place to place to avoid landslides, however, it is no longer possible to implement those actions. While a lot of research has been conducted to assess the vulnerability and risk of settlements to disasters, there needs to be more research on developing settlements in landslide-prone area and their impact on disaster management.

Results
High social influences can be found in the development of landslide-prone settlements of Giripurno Village. The community shows a high consideration on relatives in deciding their settlement location. Moreover, high consideration of kinship and social activity affects the arrangement of spaces in the house and directly affects the amount of space occupancy. Layout of houses in Giripurno Village were found to have large living room to accommodate family and community gatherings. Although high social dependences of one community can be beneficial in the disaster emergency response and recovery, it can also hinder the disaster mitigation effors by allowing development in an unsafe area, thus increase the risk of disasters.

Conclusion
This paper discuss about how the social factors can relate to the disaster management with an emphasis on the development of settlements. This paper also highlight the aspects of space occupancy which is rarely being discussed in the disaster management related research. The result obtained by this study could provide important insight into the future disaster management in the landslide-prone settlements area.
Exploring the rate and reasons for same-day cancellation of cardiac surgery after implementing joint commission international standards: a retrospective cross-sectional study
Authors: Alanazi Mohammed A. , Milton Sherran 
Published: December 2023

Abstract
Background
Same-day cancellation of cardiac surgery significantly impacts operating room management efficiency, which can be mitigated by taking preventive measures. This study aimed to explore the same-day cancellation rate of elective adult cardiac surgery, as well as the reasons for those cancellations. A retrospective cross-sectional study reviewed the records of 581 scheduled elective adult cardiac surgical cases at a single cardiac center from June 2017 to May 2018. The same-day cancellation reasons were grouped into four broad categories: nonclinical cancellations, clinical cancellations, patient-related cancellations, and 'other reason' cancellations. A case was considered canceled when it was not performed on the same day as the planned surgery.

Results
A total of 581 elective adult cardiac surgeries were scheduled during the study period, and 56 (9.63%) of these were canceled. The highest cancellation rate was due to nonclinical cancellations, with 39% of scheduled cases, followed by clinical cancellations, with a 34% cancellation rate. Patient-related cancellations accounted for 23% of cancellations, while the lowest rate was due to ‘other reasons,’ which accounted for 4% of total cancellations. The most common reason for nonclinical cancellations was the inclusion of emergency cases (n = 8; 14%). The most common reason for clinical cancellations was changes in the patient’s medical condition (n = 8, 14%). The common reason for patient-related cancellations was the refusal of surgery (n = 9; 16%). The lowest rate was for menstruating female patients (n = 2; 4%).

Conclusions
The same-day cancellation rate was 9.36%, and most of the cancellation reasons could be mitigated by implementing preventive strategies to improve the efficiency of the operating room. Preoperative preparation clinics and paying particular attention to female patients scheduled for surgery might reduce the rate of elective cardiac surgery cancellation.
Flexural performance of T-shape light-weight concrete filled steel tubular girder
Authors: El-Kherbawy Mohamed Emam , Morsy Alaa M. , Abdel-Ghaffar Maheeb , Khalifa Yasser A. 
Published: December 2023

AbstractThis paper proposes an optimization study for both structure and materials to obtain an affordable, long-span, light-weight, and fast-constructing T-shape lightweight concrete-filled steel tubular (LWCFST) girder in order to be used in bridge construction. This research was performed on a hollow steel tube of Steel-52 (yield limit 360 MPa), which was filled with LWC. A set of parameters had been investigated to illustrate its effect on T-shape LWCFST girder stiffness, toughness, resilience, and ultimate carrying load capacity in order to obtain an equivalent stiffness to that of the typically used precast concrete girder. Based on design codes (EN 1994-1-1/Euro code 4 and ANSI/AISC 360-10) that permit the use of LWC as a filler material, the parameters considered were: the thickness of the steel tube, compressive strength of the filler concrete, and the bond condition between the steel tube and filler lightweight concrete. The yielding and ultimate bending capacity were determined based on the interpreted failure criteria of T-shape LWCFST girder, considering non-linear analysis for both material and loads using ANSYSWORKBENCH software. The results showed that T-shape LWCFST girder can be employed as a significant relative economic alternative to a typical precast girder in the bridge construction field, thanks to its high stiffness/weight ratio. The lightweight concrete inside was effectively employed to delay the local web buckling of the steel tube to increase its bending capacity. In addition, it reduced the total self-weight of the bridge’s superstructure by 20% compared with a typical precast concrete girder. The dominant failure of T-shape LWCFST girders was found in the upper concrete slab due to the compression stress, even though the tensile cracks in the filler concrete occurred after reaching tensile yield stress in the steel tube. Additionally, increasing the value of friction coefficient between steel tube and lightweight concrete up to 0.8 was found to significantly affect the girder stiffness and has a slight effect after, no matter how high it is.
Exosome-mediated Delivery of miR-519e-5p Promotes Malignant Tumor Phenotype and CD8+ T-Cell Exhaustion in Metastatic PTC
Authors: Li Genpeng , Chen Wenjie , Jiang Ke , Huang Jing , Zhong Jinjing , Liu Xiaowei , Wei Tao , Gong Rixiang , Li Zhihui , Zhu Jingqiang , Shi Hubing , Lei Jianyong 
Published: December 2023

Abstract

Context
Distant metastases are the primary cause of therapy failure and mortality in patients with papillary thyroid carcinomas (PTCs). However, the underlying mechanism responsible for the initiation of tumor cell dissemination and metastasis in PTCs has rarely been investigated.

Objective
The aim of this study was to investigate effects and underlying molecular mechanisms of circulating exosomal microRNAs (miRNAs) in distant metastatic PTCs.

Methods
The most relevant circulating exosomal miRNA to distant metastatic PTCs were verified between distant metastatic PTCs and nondistant metastatic PTCs by miRNA microarray, quantitative real-time polymerase chain reaction (qRT–PCR) assays and receiver operating characteristic (ROC) curves. The parental and recipient cells of that circulating exosomal miRNA were then explored. In vitro and in vivo experiments were further performed to elucidate the function and potential mechanisms of circulating exosomal miRNAs that contribute to the development of distant metastases.

Results
We determined that PTC-derived exosomal miR-519e-5p was significantly upregulated in the circulatory system in distant metastatic PTCs. Further tests demonstrated that PTC cells can acquire a more malignant phenotype via hnRNPA2B1-mediated sorting of tumor suppressor miR-519e-5p into exosomes to activate Wnt signaling pathway via upregulating PLAGL2. Furthermore, miR-519e-5p included in PTC-derived exosomes can be transferred to recipient CD8+ T cells and aid in tumor immune escape in distant organs through inhibiting Notch signaling pathway by downregulating NOTCH2.

Conclusion
Our findings highlight the dual role of PTC-derived exosomal miR-519e-5p in distant metastasis, which may improve our understanding of exosome-mediated distant metastatic mechanisms.
Implementation of Party-Ideological Campaign against the «Sycophancy towards the West» in Tomsk Higher Education Institutions (1947-1948)
Authors: Morozov D.S. , Razgon V.N. 
Published: December 2023

The article describes the process of implementing a campaign against «sycophancy towards the West» in higher education institutions of the largest university and scientific center of Siberia — Tomsk. The role of central and regional party bodies in the organization of the campaign, the mechanism of its implementation, and the consequences for the higher school of the region are shown.
The campaign was generated by the desire of the Stalinist regime to protect the Soviet intelligentsia from the influence of liberal ideas in the face of increasing confrontation with the West in connection with the beginning of the Cold War. It included ideological measures aimed at strengthening the propaganda of «Soviet patriotism» and criticism of professors and researchers accused of "blind worship" of the culture and scientific authorities of the bourgeois West. "Moral repression" was combined with the dismissal of some professors, at the same time, due to the lack of scientific personnel, highly qualified scientists from the European part of the country who arrived in Tomsk as a result of persecution were hired at local universities.
This campaign aimed at isolating domestic science and education and more intensive use of the mobilization resources of the socialist system, on the one hand, contributed to the intensification of scientific research in areas that were considered critical for military-technological confrontation with the West and demonstrating the superiority of socialism, and on the other hand, contributed to the deepening of the backlog of most scientific areas forced to develop in isolation from the achievements of world science.
Formation of the Tuva People's Revolutionary Party in the Initial Period of the TPR
Authors: Oyun O.P. 
Published: December 2023

Based on archival materials, the history of the formation and development of the Tuva People's Revolutionary Party (TPRP) in the initial period (19211927) in terms of its performance, role and significance in the formation and development of the Tuva People's Republic, as well as the leading role of the USSR is considered. The work applied historical-genetic, historical-systemic methods to study the history of the formation of the TPR and the TPRP, historical-comparative and historical-typological methods to analyze the activities of the TPRP in different years.
As a result of the study the archival materials of the National Archive of the Republic of Tuva (NA RT) (fond 1), The Russian State Archive of SocioPolitical History (RGASPI) (Fond 495) were introduced into scientific circulation, which testify that the comprehensive assistance and leadership role of the All-Union Communist Party of Bolsheviks (b) allowed the TPRP to play a special role in strengthening the Tuvan State. Conclusions: the elite of Tuva played a huge role in the creation and functioning of the first party, but at the same time without the help and actually daily leading and guiding role of the USSR it was impossible not only the formation of the first Tuvan State, but also the development of statehood, the creation of institutions of power, social institutions, including the TPRP.
Unexpected Hepatic Manifestations of Rheumatoid Arthritis
Authors: Patel Ankur , Mathew Christo , McGowan Lucas , Bohac Sarah , Caruso Andrew , Larson Scott 
Published: December 2023

ABSTRACT
Rheumatoid arthritis is an inflammatory condition typically affecting joint spaces. However, extra-articular manifestations are common including vascular and gastrointestinal tract involvement. This disease may also manifest as nodules, although these are typically found in the extremities and are very rarely seen in the liver. When a patient presents with liver nodules, an extensive work-up is typically completed to determine infectious, inflammatory, or malignant etiologies. We report hepatic findings of rheumatoid arthritis during an extensive inpatient investigation of liver lesions.
Technology integration to promote circular economy transformation of the garment industry: a systematic literature review
Authors: Yiyan Wang , Zakaria Norsaadah 
Published: December 2023

Abstract
This study was prompted by the unsustainable issues facing the garment industry and the trend toward digitalisation in the post-coronavirus disease 2019 (COVID-19) pandemic era. COVID-19 substantially affected global trade, which caused significant garment industry stagnation due to embargoes and international restrictions. Consequently, the stagnation led to a significant inventory backlog and hindered product distribution, which compelled garment companies to turn to online commerce. A circular economy (CE) attempts to halt commodity flow and convert waste into resources; therefore, it can alleviate the substantial garment industry pollution and waste produced under a linear economy and maximise product life cycles. Industrial Revolution 4.0 incorporates technological innovation and information technology to transform the garment industry, which technologically enhances manufacturing intelligence and inspires garment industry transformation into a CE. This systematic literature review discusses the necessity of transforming the garment industry into a CE and the technological advantages and challenges to promoting sustainable garment industry development. The findings demonstrated that transforming the garment industry into a CE can not only resolve its environmental pollution and excess supply issues but can also accommodate new supply and demand requirements, such as market digitisation, consumer personalisation, and industry chain transparency. Finally, a technology integration initiative was proposed to promote garment industry transformation into a CE by digitising product development to achieve sustainable development.
Research on T-shirt-style design based on Kansei image using back-propagation neural networks
Authors: Xu Han , Ren Ruoan , Chen Han 
Published: December 2023

Abstract
Users’ Kansei image preferences have become one of the most important factors influencing purchase decisions. However, defining Kansei image can be complex. To address this issue, researchers have widely applied back-propagation neural networks due to their capacity to handle extensive data, adaptively adjust weights and biases, conduct multi-class classification and regression predictions, and offer interpretability analysis, among other features. In this study, a clothing-style design model based on users’ Kansei image cognition is proposed, using collarless T-shirts as an example. Furthermore, the attributes of T-shirt patterns are quantified using parametric graphics principles, and a semantic scale system for emotions is established through user research. The quantified sample data and corresponding semantic scale scores are then used as inputs for training a back-propagation neural network algorithm. Consequently, a design model grounded in users’ Kansei image cognition is developed, resulting in five optimal clothing design forms across various Kansei image categories. Additionally, the styles are showcased through the Style 3D platform, and the design evaluation is presented using radar charts. The results demonstrate that the five female T-shirt designs generated by the model align with users’ style preferences based on Kansei image.
An Experimental Analysis of Patient Dumping Under Different Payment Systems
Authors: Finocchiaro Castro Massimo , Lisi Domenico , Romeo Domenica 
Published: December 2023

Abstract
Physicians behave differently depending on the payment systems, giving rise to several problems such as patient dumping in which patients are refused because of economic or liability reasons. This paper tests whether and to which extent the adoption of either fee-for-service or Salary system induces physicians to practice patient dumping. Through the combination of an artefactual field experiment and a laboratory experiment, we test whether the risk of being sued for having practiced dumping can affect physicians’ behavior. Dumping is more often observed under Salary than under FFS. The introduction of dumping liability only mildly reduced dumping practice, though the provision of services increased. Our findings call for healthcare policy makers looking at the interplay between remuneration schemes and liability risks, and accounting for the trade-off between the reduction of the risk of being sued for patient dumping and the increase of the costs of the provision of medical services.