bluuebunny/crossref_metadata_2025_split huggingface dataset:
Assessing the cost-effectiveness of annual COVID-19 booster vaccination in South Korea using a transmission dynamic model
Authors: Choi Wongyeong , Shim Eunha 
Published: November 2023

IntroductionWe evaluated the cost-effectiveness of South Korea’s planned annual coronavirus disease 2019 (COVID-19) booster campaign scheduled for October 2023.Materials and methodsAn age-structured mathematical model was used to analyze the public impacts and cost-effectiveness of vaccination across three vaccination strategies: uniform allocation and prioritizing those over 65 or those over 50 years old. We calculated the incremental cost per quality-adjusted life year (QALY) from both healthcare and societal perspectives. The maximum vaccine cost for cost-effectiveness was also identified.ResultsOur analysis highlights the cost-effectiveness of South Korea’s annual COVID-19 vaccination program in mitigating health and economic impacts. The most cost-effective strategy is uniform vaccine allocation, offering the lowest incremental cost-effectiveness ratio (ICER) at US$ 25,787/QALY. However, with a relatively high attack rate, the strategy prioritizing individuals over 65 years emerges as more cost-effective, lowering the ICER to US$ 13,785/QALY. Prioritizing those over 50 was less cost-effective. All strategies were cost-saving from a societal perspective, with cost-effectiveness being more sensitive to vaccine price than to its effectiveness.DiscussionOur results imply a potential strategy shift in current vaccination plan, with uniform vaccine distribution being more cost-effective than prioritizing older adults. Early estimation of viral transmissibility and vaccine effectiveness is crucial in determining the most cost-effective vaccine allocation approach.
Idobata-Nagaya: a community housing solution for socially isolated older adults following the great East Japan earthquake
Authors: Abe Toshiki , Saito Hiroaki , Moriyama Nobuaki , Ito Naomi , Takita Morihito , Kinoshita Yuri , Ozaki Akihiko , Nishikawa Yoshitaka , Yamamoto Chika , Zhao Tianchen , Sato Mika , Tsubokura Masaharu 
Published: November 2023

IntroductionFollowing the Great East Japan Earthquake, the living environment of socially isolated older adults has become a pressing concern. In response, Nagaya, a collective housing program, was established in Soma City, Fukushima, Japan to address social isolation among older adults and support their long-term health. This study aimed to identify characteristics of individuals in Nagaya and examine the sustainability of this initiative.MethodsWe conducted a retrospective analysis of residents who were relocated to Nagaya, emphasizing their characteristics, the continuity of their stay in Nagaya, and their care certification levels, using data up to December 31, 2022. We employed Kaplan–Meier curves to analyze the duration for which residents continued to reside in Nagaya and the time leading up to the requiring care-level certification.ResultsOf 65 people who moved to Nagaya after the disaster, 30 people (46.2%) continued to live there, 21 (32.3%) died during their stay, and 14 (21.5%) moved out. The overall duration of occupancy averaged 6.39 years (SD 3.83 years). The proportion of requiring care-level certification occurrences per person-year was 0.0577 for those without care certification and 0.3358 for those with requiring support level at the time of moving in.ConclusionIn summary, Nagaya-style communal housing may offer suitable living environments for older adults with diverse needs during disasters and serve as a valuable tool for developing public policies in aging societies.
Technologies evolution in robot-assisted fracture reduction systems: a comprehensive review
Authors: Kou Wei , Zhou Peiqing , Lin Jihong , Kuang Shaolong , Sun Lining 
Published: November 2023

Background: Robot-assisted fracture reduction systems can potentially reduce the risk of infection and improve outcomes, leading to significant health and economic benefits. However, these systems are still in the laboratory stage and not yet ready for commercialization due to unresolved difficulties. While previous reviews have focused on individual technologies, system composition, and surgical stages, a comprehensive review is necessary to assist future scholars in selecting appropriate research directions for clinical use.Methods: A literature review using Google Scholar identified articles on robot-assisted fracture reduction systems. A comprehensive search yielded 17,800, 18,100, and 16,700 results for “fracture reduction,” “computer-assisted orthopedic surgery,” and “robot-assisted fracture reduction,” respectively. Approximately 340 articles were selected, and 90 highly relevant articles were chosen for further reading after reviewing the abstracts.Results and Conclusion: Robot-assisted fracture reduction systems offer several benefits, including improved reduction accuracy, reduced physical work and radiation exposure, enhanced preoperative planning and intraoperative visualization, and shortened learning curve for skill acquisition. In the future, these systems will become integrated and practical, with automatic preoperative planning and high intraoperative safety.
The value of pre-transplant coronary angiography findings in kidney transplant candidates at high risk for cardiovascular disease
Authors: Morená Leela , Al Jurdi Ayman , Adam Eduardo Leal , Verhoeff Rucháma , Palsson Ragnar , Ribas Guilherme Taborda , Hullekes Frank , Cohen Bucay Abraham , Elias Nahel , Riella Leonardo. V. 
Published: November 2023

IntroductionCardiovascular disease is a significant cause of mortality after kidney transplantation. Whether pre-transplant screening for coronary artery disease (CAD) in asymptomatic kidney transplant candidates (KTCs) is beneficial is unclear.MethodsWe conducted a retrospective cohort study evaluating post-transplant cardiovascular events in 192 high-risk KTCs who underwent pre-transplant CAD evaluation. The study aimed to identify risk factors associated with finding severe CAD on pre-transplant angiography, and to assess the relationship between screening strategies and post-transplant cardiovascular events.ResultsAt five years post-transplant, cardiovascular events occurred in 23.9% of subjects. Prior CAD history and left ventricular ejection fraction (LVEF) &lt; 50% were associated with higher odds of finding severe CAD on pre-transplant angiography. Severe CAD on angiography was associated with a higher risk of early cardiovascular events within six months of transplantation. However, coronary intervention in KTCs with severe CAD was not associated with lower rates of post-transplant cardiovascular events.ConclusionPre-transplant coronary angiography to identify severe CAD is of highest yield in KTCs with a history of CAD or an LVEF &lt; 50%. Our findings indicate that the identification of severe CAD in KTCs has prognostic significance for the early post-transplant period. Optimization of medical therapy in these high-risk KTCs may improve post-transplant cardiovascular outcomes.
Empowering stroke survivors beyond inpatient rehabilitation: the STRIDE program
Authors: Cassidy Jessica M. , Fitzgerald Ryan , Vaughn Rachel M. , Geib Anna , Marquie Maureen , Trei Anna Claire , Morrison Blaise , Lewek Michael D. , Baratta John M. 
Published: November 2023

ObjectiveThe timeframe from hospital discharge to the commencement of outpatient therapies represents a crucial yet often overlooked period in post-stroke recovery. We designed an eight-week post-stroke management program (STRIDE, Stroke Management Training and Inpatient Rehabilitation Discharge Education) targeting individuals discharging from an inpatient rehabilitation facility to home. The primary aims of this pilot study were to determine STRIDE feasibility and participant engagement.MethodsParticipants with first or recurrent stroke were enrolled. Each week, participants monitored and recorded their daily activity, completed a 15-min educational module and quiz, and partook in weekly and biweekly communication with a fellow participant and STRIDE coordinator, respectively. Feasibility was evaluated by successful initiation of STRIDE and enrollment of the target population. We also assessed participant adherence and conducted semi-structured exit interviews.ResultsOf the 99 individuals screened, 20 individuals were enrolled (7 females, 28.6 ± 15.7 days post-stroke). Several participants were unable to begin the program (n = 6) or complete the program (n = 4). Overall, participants completing at least 1 week of STRIDE (n = 14) demonstrated adherence with education module and quiz completion and communication with the STRIDE coordinator. Participant feedback from interviews was largely positive, underscoring the value of STRIDE during early post-stroke recovery.ConclusionsThese findings support the feasibility of an initiated multi-faceted stroke management program. Participant dropout was a limitation and serves as a consideration when designing future iterations of STRIDE. With the long-term goal of promoting autonomy and investment in one's continued recovery beyond the inpatient setting, STRIDE bridges the transition from hospital to home.
Prevention of implant-associated spinal infections: the GAID-protocol
Authors: Przybyl Joanna Maria , Hegewald Aldemar Andres 
Published: November 2023

ObjectiveThe purpose of this study is to investigate the efficacy of the GAID-Protocol, a bundle of intra- and postoperative infection prevention measures, to reduce implant-associated infections in patients undergoing posterior spinal fusion with instrumentation. These preventive measures are organized into a protocol that includes recommendations for four critical areas of implant protection (acronym GAID): Gloves, Antiseptics: sodium hypochlorite/hypochlorous acid (NaOCl/HOCl), Implants and Drainage-use in large wounds.MethodsWe performed a single-site retrospective review of cases undergoing posterior spinal fusion with instrumentation for primarily degenerative spinal diseases before and after implementation of the GAID-Protocol that was specifically designed to protect against implant-associated infections. The primary outcome was postoperative wound complications requiring surgical intervention, with a particular focus on infectious spondylitis/discitis.Results230 cases were included: 92 (Group A) before and 138 (Group B) after protocol implementation. Overall, wound complications requiring surgical intervention occurred in 7.6% patients in Group A and in 3.6% patients in Group B (p = 0.2297). Of these, infectious spondylitis/discitis was present in 5.4% in Group A and in none of Group B (p = 0.0096). The ratio of infectious spondylitis/discitis to other wound problems was 71% to 29% in Group A, while it was 0% to 100% in Group B (p = 0.0278). The mean time interval between the first revision surgery for wound complications and hospital discharge was significantly different, 38 days SD 20.3 in Group A and 14.4 days SD 8.6 in Group B (p = 0.0442).ConclusionsIn our study, adherence to the GAID-Protocol resulted in a shift from severe to significantly less severe and easier to treat wound complications. Adoption of the GAID-Protocol might contribute to the reduction of implant-associated infections.
How Do Older Adults in a Sub-Saharan African Community Perceive and Cope With Their Disability? An Interpretive Phenomenological Analysis
Authors: Ani Judith Ifunanya , Batisai Kezia , Ntoimo Loretta F. C. , Isiugo-Abanihe Uche C. 
Published: November 2023

Objective: The study explored the perceptions and coping strategies employed by older adults in a Sub-Saharan African community in relation to their disabilities.Methods: The research utilized an Interpretive Phenomenological Analysis methodology and conducted semi-structured interviews with a purposive sample of households. The study recruited a total of 36 older adults aged 65 years and above, aiming to capture a diverse range of insights and perspectives within the Sub-Saharan African community.Results: Three interrelated themes pertaining to the perception of disability emerged: the impact of old age, disabilities caused by diseases, and disabilities attributed to external factors such as witchcraft. In coping with disability, two interrelated themes emerged: pragmatic coping strategies and unpragmatic coping strategies.Conclusion: This study offers valuable insights into the nuanced perception of disability and coping mechanisms utilized by older adults within the Sub-Saharan African community. By exploring their lived experiences, the findings contribute to a better understanding of the challenges they face. These insights have important implications for policy development and public health initiatives.
Зрительное восприятие студентов, пользователей социальных сетей
Authors: Костригина С.В. , Розенталь С.Г. 
Published: November 2023

В исследовании принимали участие студенты КФУ возрастом 20 - 22 года, 18 человек (на основе анкетирования: активные пользователи социальных сетей - 10 человек, стаж пользования соцсетями 7-10 лет, 6-7 часов в сутки и менее активные пользователи социальных сетей - 8 человек, стаж пользования социальными сетями: 3-7 лет, 3-4 часа сутки.
С помощью НС-Психотест (2007) определяли время простой зрительно-моторной реакции (ПЗМР), показатели концентрации и устойчивости внимания, подвижности или инертности нервных процессов, зрительного восприятия и сообразительности.
Установлено, что у студентов обеих групп наблюдалась тенденция к инертности нервных процессов. Показатели сообразительности и пространственных отношений демонстрируют склонность менее активных пользователей социальных сетей к более высокой эффективности зрительного восприятия, по сравнению с активными пользователями социальных сетей.

Ключевые слова: пользователи социальных сетей, ПЗМР, концентрация и устойчивость внимания, нервные процессы, зрительное восприятие.
Химическая модификация лидокаина с целью улучшения его фармакологических свойств
Authors: Михеева А.В. , Долгова Е.С. , Михеева Л.А. 
Published: November 2023

Лидокаин гидрохлорид - 2-диэтиламино-2,6-ацетксилидида гидрохлорид, моногидрат представляет собой белый или почти белый кристаллический порошок без запаха.
Разнообразие свойств лидокаина может быть достигнуто не только за счет использования разных сырьевых источников, но и за счет химической модификации лидокаина. Это направление позволяет модифицировать молекулу лидокаина фрагментами, представляющими собой остатки некоторых альдегидной, гидроксильных и карбоксильной групп, с целью получения более эффективных, длительно действующих и менее токсичных антиаритмиков.
Нами были синтезированы производные лидокаина с глицином и цистеином. Ранее нами также были синтезированы аминопроизводные лидокаина (Долгова Е.С., Михеева Л.А. 2019).

Ключевые слова: лидокаин, глицин, цистеин, синтез, выход, ИК-спектр.
Aplikasi Metode VIKOR untuk Menentukan Penerimaan Proposal Kegiatan Desa
Authors: TO SUKAMTO , Andriyani Yanti , Daqiqil Id Ibnu 
Published: November 2023

Kantor Wali Nagari Simpang memiliki proposal kegiatan desa. Penilaian proposal dilakukan secara langsung ke lapangan dan dilakukan secara manual, sehingga menungkinkan terjadinya kesalahan. Untuk itu diperlukan sistem pendukung keputusan menggunakan metode VIKOR. Hasil akhir dari lima proposal yang diajukan dengan kriteria yang ditentukan, memberikan rekomendasi bahwa proposal Jembatan Kp. Batuang - Bukik Putuih merupakan proposal terbaik dan layak untuk didanai
Implementasi Algoritma Random Forest Regression untuk Memprediksi Hasil Panen Padi di Desa Minanga
Authors: Nur Nahya , Wajidi Farid , Sulfayanti Sulfayanti , Wildayani Wildayani 
Published: November 2023

Desa Minanga, Kecamatan Bambang, Kabupaten Mamasa penduduknya melakukan budidaya tanaman padi yang biasanya hasil panen setiap musimnya mengalami fluktuasi yang seringkali terjadi penurunan atau pun peningkatan yang tidak stabil. Penelitian ini diharapkan dapat membantu dalam memprediksi hasil panen padi sesuai dengan kriteria dan data yang ada sebelumnya seperti luas lahan, jumlah bibit, jenis pupuk, curah hujan, hama dan gulma, pengendalian hama dan gulma, dan sistem penanaman padi yang digunakan (jajar legowo), dengan menerapkan algoritma Random Forest Regression. Evaluasi kinerja algoritma diukur dengan menggunakan Root Mean Squared Error (RMSE), Mean Absolute Percentage Error (MAPE) dan koefisien determinasi (RÂ²), hasil dari model Random Forest yang didapatkan dari 9 pohon, variabel yang memiliki nilai paling tinggi pada variabel importance adalah variabel luas lahan. Sehingga dari model tersebut diperoleh nilai akurasi 95,11%, Nilai MAPE pada model ini yaitu 4,884%, nilai RMSE yaitu 0,250 dan nilai RÂ² yaitu 0.99.
Strategi Peningkatan Kualitas Pelayanan di Restoran Torimoshi Yakitori Bar Semarang
Authors: Fikri Raden Muhammad Mukhlis , Sukresna I Made 
Published: November 2023

Dalam bisnis kuliner pelanggan merupakan prioritas utama, upaya yang dapat dilakukan restoran untuk meningkatkan kepuasan pelanggan yaitu melihat kebutuhan dan keinginan pelanggan menjadi faktor utama dalam keberhasilan sebuah restoran. Salah satu faktor utama dalam memenuhi kebutuhan dan keinginan pelanggan yaitu kualitas pelayanan dari sebuah restoran (Maimunah et al., 2019). Tujuan dari penelitian ini adalah untuk memberikan strategi dalma meningkatkan kualitas pelayanan di restoran Torimoshi Yakitori Kota Semarang. Penelitian ini menggunakan metode kualitatif untuk mendeskripsikan fenomena-fenomena yang terjadi dengan Teknik populasi data melalui survey dan wawancara terhadap beberapa responden. Berdasarkan hasil pembahasan pada penelitian ini ditemukan masih terdapat kendala dari karyawan dalam memberikan pelayanan yang baik di Torimoshi. Kendala yang terjadi seperti kurang fokus dan terampilnya karyawan yang menyebabkan proses penyajian pesanan menjadi terhambat, ketidak telitian karyawan sebelum menyajikan pesanan dan kurangnya fasilitas westafel, kipas angin, dan tempat sampah di area konsumen. Dengan demikain upaya-upaya yang dapat dilakukan manajemen restoran antara lain; mengadakan pelatihan kembali terhadap semua karyawan dalam meningkatkan keterampilan setiap karyawan serta selalu melakukan briefing sebelum memulai shift. Melakukan pendampingan karyawan oleh supervisor sehingga karyawan dapat menerapkan standar operasional restoran yang sudah ada. Melakukan penambahan fasilitas berdasarkan urgensi dan prioritas dari rencana kedepan dari restoran, dimana dengan penambahan fasilitas yang diharapkan oleh konsumen, dapat meningkatkan performa pelayanan di Torimoshi.
Pengaruh Gaya Kepemimpinan, Komitmen Organisasi dan Lingkungan Kerja Terhadap Kinerja pada Lembaga Layanan Pendidikan Tinggi Wilayah XV yang Dimediasi oleh Motivasi Kerja
Authors: Manuain Erna , Niha Simon Siha , Man Stanis , Manafe Henny A. , Tule Philipus 
Published: November 2023

<p>Kepemimpinan sangat menentukan kemajuan dan kemunduran organisasi. Sebab kepemimpinan yang sukses menunjukkan bahwa pengelolaan suatu perusahaan berhasil dilaksanakan dengan sukses pula. Tujuan dari penelitian ini untuk mengetahui gambaran dan menguji kinerja serta peranan motivasi kerja sebagai mediator dari gaya kepemimpinan, komitmen organisasi dan lingkungan kerja pada Lembaga Layanan Pendidikan Tinggi Wilayah XV. Jenis penelitian adalah penelitian kuantitatif, jenis data digunakan yakni data primer dan data sekunder, teknik analisis data adalah analisis statistik deskriptif dan analisis statistik inferensial, sedangkan Sampel pada penelitian ini berjumlah 57 responden. Hasil analisis statistik deskriptif menunjukkan bahwa gambaran tentang gaya kepemimpinan pada Lembaga Layanan Pendidikan Tinggi Wilayah XV adalah kurang baik, komitmen organisasi, lingkungan kerja, dan kinerja pada Lembaga Layanan Pendidikan Tinggi Wilayah XV adalah baik dan motivasi kerja pada Lembaga Layanan Pendidikan Tinggi Wilayah XV adalah cukup baik. Hasil analisis statistik inferensial menunjukkan : 1). Gaya kepemimpinan dan lingkungan kerja berpengaruh signifikan terhadap motivasi kerja. Sedangkan komitmen organisasi berpengaruh tidak signifikan terhadap motivasi kerja; 2). Gaya kepemimpinan dan motivasi kerja berpengaruh tidak signifikan terhadap kinerja. Sedangkan komitmen organisasi dan lingkungan kerja berpengaruh signifikan terhadap kinerja; 3). Motivasi kerja tidak dapat memediasi pengaruh gaya kepemimpinan, komitmen organisasi dan lingkungan kerja terhadap kinerja pada Lembaga Layanan Pendidikan Tinggi Wilayah XV. Kontribusi gaya kepemimpinan, komitmen organisasi dan lingkungan kerja terhadap motivasi kerja sebesar 88.40% dan sisanya 11,60 % dijelaskan oleh faktor lain yang tidak diteliti dalam penelitian ini. Sedangkan kontribusi gaya kepemimpinan, komitmen organisasi, lingkungan kerja dan motivasi kerja terhadap kinerja sebesar 89,10%,dan sisanya 10,90 % dijelaskan oleh faktor lain yang tidak diteliti dalam penelitian ini.</p>
Citizen science expanding knowledge: a new record of the lizard Heterodactylus imbricatus (Squamata, Gymnophthalmidae) in south-eastern Brazil
Authors: Zocca Cássio , Barreto-Lima André , Daleprane Dulce , Ghilardi-Lopes Natalia 
Published: November 2023

Through citizen science projects, like Projeto Bromélias, community members contribute valuable data on species diversity, notably those with low detectability like theHeterodactylus imbricatuslizard. A recent observation in the State of Espírito Santo (south-eastern Brazil), amidst coffee and eucalyptus crops, highlights the utility of widespread technology use in tracking and documenting wildlife. Such initiatives are especially beneficial for mapping the distribution of rare, endemic or endangered reptiles. Therefore, we advocate for more citizen science initiatives near protected areas, involving local communities.We provide a new record for the speciesHeterodactylus imbricatus, a microteiid lizard of low detectability from the Atlantic Forest of south-eastern Brazil.Heterodactylus imbricatus(Rio de Janeiro Teiid) was recorded near the protected area "Reserva Biológica Augusto Ruschi" by a citizen volunteer who contributes herpetofauna records to the Bromelias Project (https://www.inaturalist.org/projects/projeto-bromelias).Heterodactylus imbricatusis a very poorly-known species in the localities where it occurs, probably due to its fossorial habit, genera's restricted occurrence range, habitat specificity and the absence of proper survey methods fitted to fossorial species, such as the utilisation of pitfall traps. By publishing the records of volunteer citizens, we hope that more people will contribute to increase the knowledge of biodiversity in the mountainous region of Espírito Santo State and expand our collective knowledge.
The Digital Markets Act (DMA) and the Future of Transatlantic Relations
Authors: Tzogopoulos George N. 
Published: November 2023

Le 1 er novembre 2022, la loi sur les marchés numériques (DMA) est entrée en vigueur. Elle avait été proposée par la Commission européenne en décembre 2020 et approuvée par le Parlement européen et le Conseil en mars 2022. La loi sur les marchés numériques fait écho à la détermination de l’UE à façonner la nouvelle économie mondiale et à mettre en œuvre concrètement le concept de souveraineté numérique en proposant une réglementation renforcée qui affecte le fonctionnement des entreprises « Big Tech ». Cependant, elle crée également des défis dans une période où les États-Unis et l’UE intensifient leur dialogue sur les questions technologiques. Si les critiques américaines à l’égard du DMA sont relevées dans l’UE, l’ambition générale d’autonomie stratégique européenne, qui évolue dans la sphère numérique, n’ébranle pas l’unité transatlantique.