bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluasi Penerapan Standar Pelayanan Farmasi Klinik Di Apotek Kabupaten Magelang
Authors: Heroweti Junvidya , Rahmawati Fitri , Ikhsan Muhammad 
Published: December 2023

Standar pelayanan farmasi (PMK 73/2016) menjadi tolak ukur pelayanan kefarmasian pada apotek meliputi compounding dan dispensing, pengkajian resep, konseling, pelayanan informasi obat, pelayanan kefarmasian di rumah, pemantauan terapi obat dan monitoring efek samping obat. Berdasarkan hasil observasi apotek di Kabupaten Magelang, terdapat beberapa apotek yang tidak terdapat apoteker selama apotek buka. Selain itu ditemukan juga tenaga kerja selain tenaga kefarmasian yang ikut serta dalam pelayanan farmasi klinik. Penelitian ini untuk mengevaluasi penerapan standar pelayanan farmasi klinik untuk apotek di sekitar Kabupaten Magelang. Penelitian dilakukan secara deskriptif non eksperimental dengan metode Cross-Sectional. Pemilihan sampel secara random dengan jumlah 25 apotek di wilayah Kabupaten Magelang. Pengambilan data menggunakan kuesioner. Data dianalisis dengan SPSS secara deskriptif kuantitatif. Evaluasi penerapan standar pelayanan farmasi klinik pada apotek di sekitar Kabupaten Magelang diperoleh hasil rata–rata pengkajian dan pelayanan resep 93,28% (kategori baik), compounding dan dispensing 93,89% (kategori baik), pelayanan informasi obat 65,28% (kategori cukup), konseling 66,53% (kategori cukup), pemantauan terapi obat 45,37% (kategori kurang), dan monitoring efek samping obat 30,33 % (kategori kurang).
Simulation analysis of low back forces in Snatch and Clean & Jerk movements via digital human modelling
Authors: Soares Denise , Abbady Karim , Kasap Suat , Shabanliyski Dimitar 
Published: December 2023

BACKGROUND: Weightlifting is an Olympic sport for dynamic strength and power, and requires the execution of different lifting techniques It is important to analyze the forces subjected to the lower back during weightlifting movements to prevent injuries. Digital Human Modeling (DHM) is a powerful tool that can be used to analyze and optimize the performance of humans while doing their work or activities. OBJECTIVE: The purpose of this study is to present a simulation analysis of the lower back forces during the execution of two weightlifting techniques: Snatch (SN) and Clean & Jerk (CJ), with different loads and for both genders. METHODS: Digital Human modelling through JACK simulation package was used analyze the forces exerted on the lumbosacral area (L5-S1) of the lower back in order to determine the risk for low back injuries. The level of compression and shear forces recommended by the literature have been set as thresholds. The simulaitons were performed in male and female models, with loads from 20–100 kg. RESULTS: The results show that any weight higher than 60 kg in both movements poses risk for the weightlifters in terms of compression and shear forces. It has been observed that weightlifters can lift greater loads in the CJ technique compared to the SN technique. Furthermore, females are able to lift higher loads with lower risk of injuries. CONCLUSION: Weightlifting is a high-risk activity due to the high levels of shear and compression forces that the body is exposed to during the lifting techniques. Digital Human Modeling holds significant value due to their ability to facilitate the exploration of diverse conditions within a safe environment, devoid of any potential harm to human subjects.
Effects of an eight-week physical exercise program on low back pain and function in fruit workers: A randomized controlled trial
Authors: Passos Muana Hiandra Pereira dos , Pícon Sol Patrícia Beltrán , Batista Gabriel de Amorim , Nascimento Vinícius Yan Santos , Oliveira Felipe Augusto da Silva , Locks Francisco , Pitangui Ana Carolina Rodarti , de Araújo Rodrigo Cappato 
Published: December 2023

BACKGROUND: Low back pain is prevalent in workers’ health and functional performance. OBJECTIVE: To evaluate the effects of a physical exercise program on low back pain and disability in fruit workers. METHODS: This randomized controlled trial assigned 44 workers (37 ± 9 years) to two groups. The experimental group consisted of 10 men and 12 women with an average age of 38 (± 9) years, and the control group consisted of 8 men and 14 women with an average age of 36 (± 10) years. The experimental group (EG) performed a program of strength and flexibility exercises for eight weeks, twice a week. The control group (CG) received minimal care, with a booklet with guidelines for performing exercises. The primary outcomes included changes in perceived disability and the intensity of pain evaluated by the Rolland-Morris questionnaire and the Numerical Pain Scale, respectively. All outcomes were measured at baseline and after eight weeks of intervention. RESULTS: A significant difference was observed in the within-group analysis, with a mean reduction in pain intensity in the EG and CG of -4.55 (95%CI -7.01 to -2.09) and -3.81 (95%CI 1.72–5.90), respectively. For disability, a reduction of -4.45 (95% CI -8.89 to -0.02) was observed in the EG and of -4.43 (-7.38 to -1.48) in the CG. There were no significant differences in the between-groups analysis. CONCLUSIONS: The exercise program was not superior to using the educational booklet. However, both interventions showed substantial decreases in pain and disability levels.
The effect of an explosive shock wave on the plate of a protective structure of a critical infrastructure
Authors: Sakharov Volodymyr , Lytvyn Oleksandr 
Published: December 2023

The article presents the outcomes of an analysis on the stress-strain conditions of reinforced concrete structures subjected to an explosive shock wave resulting from the detonation of a combat unit from a kamikaze drone against a protective screen. When designing protective structures for critical infrastructure, employing computer simulation enables an assessment of the genuine impact of explosive loading on the structural elements' strength. The active phase of explosive loading is exceptionally brief, lasting only a fraction of a second. Under such circumstances, modeling is best performed using explicit methods of direct integration in time.
The structure considered in this work is a reinforced concrete slab supported by a metal beam cage with I-beam cross-sections, topped with a sand backfill. The study was executed within the SIMULIA Abaqus software suite, incorporating models depicting nonlinear material behavior in a three-dimensional context. Discretely positioned reinforcement was considered for reinforced concrete structures, and the "Concrete Damage Plasticity" model was applied for concrete, accounting for damage accumulation. The devised computational scheme for the shelter represents a section of the protective structure's roof under conditions of cyclic symmetry.
The article elucidates the core principles of incorporating explosive loading according to algorithm CONWEP.The results demonstrate that during the detonation of a kamikaze drone, an explosive wave created a crater in the sand backfill, exposing the slab. The study illustrates the development of damage in the reinforced concrete slab at various time intervals. Despite the identified damage to the slab, the protective structure overall withstood the explosive load. The intensity of the explosive shock wave diminishes significantly as it propagates away from the explosion site.
Investigation of the stress-strain state of foundation structures in determining the vertical stiffness of piles using different software systems
Authors: Pidlutskyi Vasyl , Piatkov Oleksandr , Behan Vasyl 
Published: December 2023

The results of numerical modeling of the interaction between a multi-storey building on a pile foundation and the soil base in the "Lira-SAPR" software are presented. A comparison of the stress-strain state of foundation structures was performed using different methods for determining vertical stiffness (Rz) in single-node FE 57 (this element is designed to model the behavior of a pile together with the surrounding soil, similar to FE 56, and can implement the interaction with the "SOIL" system). Piles were modeled by a chain of single-node FE 57 connected by vertical bars.
In the first variant, the calculation of the building was performed in the "Lira-SAPR" software. To determine the vertical stiffness in FE 57, a soil model with physical-mechanical characteristics was created, and layering was defined according to the engineering-geological cross-section in the "SOIL" system. The calculation of vertical stiffness took into account mutual influence and the model of the conditional foundation.
In the second variant, the determination of vertical stiffness (Rz) in FE 57 was carried out using the "Plaxis 3D" software. The overall model of above-ground structures, foundations, and all necessary loads were created in the "Lira-SAPR" software. Subsequently, an export to "Plaxis 3D" was performed, where the soil was previously modeled as a three-dimensional soil mass (with characteristics and strengths of layers similar to those created in the "SOIL" system) using the "Hardening soil" behavior model. After the import into "Plaxis 3D," the analysis of the "Soil-Foundation-Structure" system was conducted, and the obtained values of vertical stiffness (Rz) in FE 57 were exported back to "Lira-SAPR". After the export of "refined" values of vertical stiffness to "Lira-SAPR", a general static analysis and comparison of the stress-strain state of foundation structures with the first calculation variant was performed.
It was established that the vertical stiffness in FE 57 in the first variant is higher than in the second, accordingly, the total displacements for the first variant are smaller. The importance of using the connection between "Lira-SAPR" and "Plaxis 3D" or other specialized geotechnical software complexes was demonstrated to obtain more accurate results of the interaction of the "Soil-Foundation-Structure" system due to the possibility of using nonlinear soil models to better describe the behavior of the foundation.
PROBLEMS OF PRESERVATION AND REVITALIZATION OF THE TERRITORY OF THE NATURAL MONUMENT – HISTORICAL "KADETSKYI HAI"
Authors: Chernyshev Denys , Ivashko Yulia , Mamedov Alirza , Dmytrenko Andrii , Ivashko Oleksandr , Kravchuk Oksana 
Published: December 2023

The article is devoted to the study, preservation and revival of the territory of the historical natural monument – Kadetskyi Hai. This is a unique ecosystem with the river Vershynka, lakes and a large oak grove, which has repeatedly undergone changes. This territory is known from chronicle sources of princely times and is depicted on historical maps, it is described as an important green zone in the suburbs of ancient Kyiv, which played several functions: recreational, economic, residential, military. After 1917, the mass destruction of the green massif of Kadetskyi Hai began, which was intensified by blocks of massive construction in the 1960s. The purpose of the research: to systematize historical information about the Kadetskyi Hai, to identify its features, to identify the problems associated with the process of organizing the remaining green areas today, and to provide proposals for their solution.
According to the developed proposals, it is necessary to clean up and arrange the bed of the Vershynka River, setting up a sanitary protection zone around it. As an option, it is proposed to move the channel further from the railway track and turn it into a place of rest. Since the part of the “Sputnyk” park in the part of the White Gazebo (Bila Altanka) and the Vershynka River is unorganized and cluttered, it is proposed to organize it.
The disorder of green zones remains a problem, both in Sputnyk Park and landscaping within residential neighborhoods. In fact, the areas of mass construction of the 1960s have turned into “sleeping neighborhoods” over time, where there is a lack of public service facilities, parking lots, organized recreation areas, sports and children's playgrounds.
A separate problem is related to the disorganization of green spaces. The authors investigated the greening of the Pershotravnevyi residential area on the territory of the former Kadetskyi Hai. This neighborhood is characterized by a terraced terrain, where medium-story brick houses are located on the upper and lower levels of the natural slope. In the thickness of the slope there is an extensive network of communications, so it remains undeveloped. In recent years, because of the war, slope clearing and removal of self-seeding trees and bushes have not been carried out, so this area has taken on the appearance of a forest park made of deciduous trees.
ERGONOMIC FEATURES OF THE FORM OF THE ARCHITECTURAL CENTER IN BACKGROUND SCHOOLS OF FUTURE WITH THE FUNCTION OF ACCOMMODATION
Authors: Ivantsev Viktor , Obynochna Zoriana 
Published: December 2023

The article highlights the nutritional problems of creating a functional and developing school, which includes the ergonomic features of children and is best suited to the needs of the “growing generation”. The residence function allows children to fully learn the initial process, communicate with other children and even spend an hour with their parents on weekends. Ergonomics is an invisible part of every person’s life, and it also makes life more comfortable and easier. The statistics also provide recommendations for technologies and materials that should be used in teaching and living schools with the function of living.
It is worth noting that a school that takes into account all the ergonomic features of its visitors has a positive effect not only on the comfort of students, but also on their health, which is extremely important in modern society. Regardless of the fact that most schools in Ukraine do not meet the current benefits of ergonomics and comfort, in the future it is possible to correct by establishing clear rules for the design of current schools for future generations. A short history of boarding schools allows us to understand how the concept of school has evolved and the standards and needs of students have changed. Schools of the future, which will insure and ensure all the needs of students, readers and staff, this standard, Ukrainian schools will bend to any responsibility, as they want to give high-quality education and start teaching students on the main river no.
DEFORMABILITY AND CRACK RESISTANCE OF REINFORCED CONCRETE AND FIBER CONCRETE BEAMS
Authors: Surianinov Mykola , Vyhnanets Marina 
Published: December 2023

The work presents the results of the study of deformability and crack resistance of reinforced concrete beams with additional steel fiber reinforcement. Beam samples of three series were produced (three in each series): series I ― beams made of ordinary concrete; II series ― steel-reinforced concrete beams; III series ― beams of combined section, in which the lower zone (0.5 from the height of the beam) is made of steel fiber concrete, and the upper zone is made of ordinary concrete. One sample of each series was made from one batch. At the same time, material samples were made from the same batch. Fiber, the total volume of which was 1% of the volume, was uniformly added to the composition of the concrete mass for the II and III series of samples during mixing. The load was applied in increments of 1 ton. Deformations were determined using strain gauges, watch-type indicators with a division value of 0.01 mm in the middle of the beam span. At each stage, a certain amount of time was required to read the instruments, find and fix the cracks, as well as to measure the length and width of their opening using a Brinell tube. The tests showed that the deformability of the beams of the three series and the character of the crack formation are significantly different from each other. Moreover, the series III beam with combined reinforcement occupies an intermediate position in terms of these characteristics. Thus, by the end of the tests, the reinforced concrete beam (series I) had 19 cracks, the fiber concrete beam (series II) ― 28, the beams with combined reinforcement (series III) ― 23. At the same time, the maximum final crack opening width for beams I, II, III series was 0.8 mm, 0.1 mm (one crack) and 0.1 mm (two cracks), respectively. Cracks in a fiber concrete beam are much smaller in width. And the maximum length of the cracks here turned out to be the largest ― 31.3 cm, while in the beams of the I and III series this value was 25.5 cm and 20.4 cm, respectively.
The analysis of the given results shows that the best indicators of crack resistance are revealed by beams with full dispersion reinforcement. The use of fiber allows you to change the nature of the destruction process. Unlike ordinary concrete, in which this process occurs almost instantaneously, in fiber concrete there is no brittle failure, and the beam continues to resist the load, and the nature of the failure changes from brittle to viscous.
FORMATION OF THE ART DECORATION OF THE DUNGHUAN CAVES UNDER THE INFLUENCE OF EXTERNAL FACTORS
Authors: Shiru Wang 
Published: December 2023

The influence of external factors on the formation of the figurative concept of Dunhuang wall paintings is analyzed. The purpose of the article is to highlight the processes of forming the artistic decoration of Dunhuang caves under the influence of external factors.
The relevance of the research topic is due to the need to draw the attention of world scientists to the problem of research and preservation of the Dunhuang complex, since some of the frescoes are in a state of emergency and the exchange of experience of restorers from different countries is necessary for their preservation.
The tasks of the study were to determine the role and significance of external factors in the activation or decline of the Dunhuang complex, and based on this to argue the dependence of the figurative concept of Dunhuang wall paintings on external factors (political, ideological, economic, social, natural and climatic).
It is proved that the appearance of the Dunhuang Buddhist cave temple complex and the processes related to its construction were largely determined by external factors: at first, the commitment of the rulers of China to the new religion of Buddhism contributed to the activation of the process of creating new sanctuaries, and later under the influence of local philosophical and religious traditions as well as cultural and artistic preferences, there is a transformation of Buddhist fresco traditions borrowed from India, which acquires a local color in the conditions of China. It should be noted that while preserving the general canonicality of wall painting in the process of developing artistic skills, it acquires greater realism and the means of artistic expression are diversified with portraits of benefactors, scenes from their lives and landscape compositions.
Research on the therapeutic effectiveness of the veterinary medicinal product “Surfadev” in complex therapy for stimulating sexual desire in cows
Authors: Katsaraba O. A. , Sachuk R. M. , Kostyshyn Ye. Ye. , Stravskyy Y. S. , Kostyshyn L.-M. Ye. 
Published: December 2023

Clinical studies were conducted in the treatment of hypofunction of the ovaries to increase the fertility of cows and heifers with the newly created drug “Surfadev” (solution for injections) in complex therapy. VLZ “Surfadev” (solution for injections). The drug stimulates the secretion of gonadotropins by the pituitary gland in a maximum of 2–3 hours after administration. The increased content of gonadotropins in the blood persists for 4–5 hours after administration. Unlike natural luliberin, the biological activity of the drug is 50 times greater, which allows the use of this drug in microdoses and short courses. The drug decomposes under the influence of enzymes more slowly than natural luliberin, which provides a stronger biological effect on the pituitary gland. “Devivit Complex” is a complex multivitamin preparation (Vitamins A, D3, E, B1, B2, B3, B5, B6, B12), which is used to correct and normalize metabolic processes in animals. Vitamins included in the preparation take part in biochemical processes in animal organisms (in the form of enzyme vitamins, hormone vitamins, antioxidants). When ovarian function is stimulated or corrected, 90.0 % of the treated animals show the arousal stage of the sexual cycle within 3–15 days, and their fertilization rate from the first insemination is 70.0 % on average. The high efficiency of using “Surfadev” in combination with “Devivit Complex” for ovarian hypofunction has been established. 83.3–95.6 % of the treated cows showed sexual desire, and the fertility from the first insemination reached 70.0 %. Further studies will be the next stage of pre-registration trials aimed at studying the effectiveness of the veterinary drug “Surfadev” (solution for injections) in complex therapy in the treatment of ovarian hypofunction and follicular cysts, which is mandatory material of the fourth part “Preclinical and clinical documentation” of the dossier for this medicine.
Synthesis of silica chitosan oligosaccharides nanoparticles
Authors: Salazar-Navarro Alexis A. , Rivera-Reyna Nallely E. , González-Mendoza Daniel 
Published: December 2023

Objective: To obtain chitosan oligosaccharides (COS) and evaluate COS uses for the obtention of nanosystem based on silica as vehicle and compare the COS-silica nanosystem with the chitosan (Chi) precursor system as Chitosan-silica nanosystems.
Design/methodology/approach: A combination of hydrolysis chemical and mechanical (microwave assisted) were used to obtain COS with the oxidative action of hydrogen peroxide. Sol-Gel adapted method was used to synthetize silica nanoparticles (SiNPs) from sodium metasilicate and the electrostatic interactions between SiNPs and Chi/COS were used to functionalize the SiNPs surface with Chi/COS.
Results: Nanosystem composed from COS and SiNPs were obtained successful as A COS-SiNPs and C COS-SiNPs with particle size of 139.35 nm and 251.8 nm and zeta potential of 30.40 mV and 34.67 mV respectively with antimicrobial activity against Escherichia coli and Staphylococcus aureus.
Limitations on study/implications: Stabilize the systems compound of chitosan-silica nanoparticles due to the molecular weight of chitosan which loss the stabilized the SiNPs suspension and due the incompatibility of both systems pH.
Findings/conclusions: COS and COS-SiNPs stable systems were obtained with an improvement of the antimicrobial activity of the system in contrast of Chi-SiNPs systems.