bluuebunny/crossref_metadata_2025_split huggingface dataset:
Young-onset Alzheimer’s dementia mimicking progressive myoclonic epilepsy spectrum
Authors: Mahale Rohan , Arunachal Gautam , Dutta Debayan , Venkatachalam N. , Padmanabha Hansashree 
Published: October 2023

Abstract
Background
Young-onset Alzheimer’s dementia (YOAD) refers to the onset of disease before the age of 40 years. Classical AD typically presents with memory impairment with involvement of other cognitive domains like language, visuospatial orientation. On contrary, YOAD shows phenotypic heterogeneity in the form of predominant psychiatric disturbances apart from dementia and rarely seizures, cerebellar ataxia. We report a 36-year-old lady with dementia, myoclonus, seizures and cerebellar ataxia of 3 year duration mimicking progressive myoclonic epilepsy (PME) spectrum who had novel missense mutation in PSEN1 gene (L226F) suggestive of YOAD.

Case presentation
A 36-year-old lady presented with seizures in the form of generalized tonic–clonic seizures of 3 year duration followed by multifocal myoclonic jerks, cognitive decline of 2 year duration and imbalance while walking of 1 year duration. Montreal cognitive assessment (MOCA) score was 6/30. Addenbrooke’s cognitive examination III (ACE-III) score was 16/100. The mental status examination showed diffuse impairment of lobar functions. Brain magnetic resonance imaging showed diffuse cerebral and cerebellar atrophy. Skin biopsy did not show Lafora bodies or dermal inclusions on electron microscopy. Whole exome sequencing showed pathogenic missense variant NM_000021.4(PSEN1):c.676C > T (p.Leu226Phe) in PSEN1 gene suggestive of YOAD.

Conclusions
YOAD due to PSEN1 mutation has to be considered in patients with cerebellar ataxia, seizures, myoclonus, dementia with psychiatric disturbances. This case highlights the high index of suspicion for differential diagnosis of YOAD in patients with young-onset dementia with ataxia, seizures and myoclonus.
An overview of the status, productivity and determinants of improved forage technology adoption in Ethiopia: a review
Authors: Tesfaye Mamaru , Tessema Lemma 
Published: October 2023

AbstractIn Ethiopia, the adoption of improved forage technology is low despite the fact that improved technology adoption can play a pivotal role in boosting livestock production and productivity in general and the dairy sub-sector in particular, thereby contributing to poverty reduction and food and nutrition security. This low adoption of improved forage technology is constrained by various socioeconomic, institutional, and biophysical factors. We conducted a literature search on the reputable journal database by searching for “improved forage technology”, “determinants of forage technology”, “adoption”, “status of forage production in Ethiopia”, and “forage production limitations”. Moreover, we conducted a literature search on key national-level research institutions, the Ethiopian Society of Animal Production Proceedings, the Central Statistics Agency (CSA) of Ethiopia, and conference proceedings and abstracts of societies and other relevant databases related to our keywords. This review article, therefore, highlights important issues that potentially constrain farmers` improved forage technology adoption and implementation in Ethiopia. Previous empirical study findings, analyzing the determinants of forage production technology adoption underscored that economic, technological, sociocultural, demographic, and institutional factors are the most important determinants of improved forage technology adoption and diffusion. Generally, to intensify the likelihood of the adoption of improved forage technologies, policymakers and concerned stakeholders should focus on strengthening the research-extension-farmers (R-E-F) linkage, adult education, and capacity building, coaching farmers to access improved forage seeds, information on forage husbandry and feeding, strengthening extension systems as well as capabilities which can improve the livelihoods of smallholder dairy farmers. Finally, the technology developer should incorporate the needs and perceptions of farmers through technology design and development; and consider the key demand and supply side during technology development, which enhances the adoption of the technology more easily. Therefore, our empirical review highlights the importance of addressing the aforementioned technology adoption constraints to improve the adoption and diffusion of improved forage technologies. This in turn, would help to improve the livelihoods of rural smallholder dairy farmers.
Kashmiri Futures
Authors: Junaid Mohamad , Misri Deepti , Zia Ather 
Published: October 2023

Abstract
This special issue inaugurates a scholarly and creative conversation that seeks to detach the future of Kashmir from the narrative, aesthetic, and political frames of powerful nation-states that have sought to keep Kashmiris confined to a long and seemingly enduring colonial present. It seeks, moreover, to inspire radical imaginations of possible futures in danger of foreclosure by occupying states, and asks us to think about occupation as a temporal as well as spatial regime.
Notes on Kashmiri Visualities
Authors: Zehra Ifsha 
Published: October 2023

Abstract
This essay explores the various modes of visualities and visual production in Kashmir. It begins with mapping the existing state visualities that use hypervisibilization, victimization, criminalization, and depoliticization as modalities to represent Kashmir. In recent years, long-standing counternarratives to these representations have met with increasing repression, engendering a visual stagnancy. Earlier, countervisuals by photojournalists confronted state visualities by directing the gaze toward Kashmiri bodies. This essay argues that the repeated production and circulation of these realistic images have also reached a point of visual fatigue. At this juncture of a seeming visual impossibility, the essay proposes creative configurations and visual imaginaries through artistic visioning as a means to continue the work of visual production.
Decolonial Futures
Authors: Caronan Faye , Avalos Natalie , Minami Kealohilani , Sarmiento Meta , Wahdan Reema , Zia Ather , Upadhyay Nishant 
Published: October 2023

Abstract
This roundtable showcases how different Asian, Pacific Islander, and Indigenous communities in Colorado are fighting for sovereignty of their homelands. It reorients the question of “homelands” to highlight the experiences of communities whose homelands remain occupied by settler-colonial and imperial nation-states, like the United States, India, Israel, and China. Participants speak to the struggles of sovereignty of their communities and communities they work with, unsettling epistemological frameworks to disrupt normative understandings of home, migration, and diaspora.
Vertebral Compression Fracture After Spine Stereotactic Body Radiotherapy: The Role of Vertebral Endplate Disruption
Authors: Dibs Khaled , Facer Benjin , Mageswaran Prasath , Raval Raju , Thomas Evan , Gogineni Emile , Beyer Sasha , Pan Jeff , Klamer Brett , Ayan Ahmet , Bourekas Eric , Boulter Daniel , Fetko Nicholas , Cochran Eric , Zoller Ian , Chakravarthy Vikram , Tili Esmerina , Elder J. Bradley , Lonser Russel , Elguindy Ahmed , Soghrati Soheil , Marras William , Grecula John , Chakravarti Arnab , Palmer Joshua , Blakaj Dukagjin M. 
Published: October 2023

BACKGROUND AND OBJECTIVES:
Vertebral compression fracture (VCF) is a common, but serious toxicity of spinal stereotactic body radiotherapy (SBRT). Several variables that place patients at high risk of VCF have previously been identified, including advanced Spinal Instability Neoplastic Score (SINS), a widely adopted clinical decision criterion to assess spinal instability. We examine the role of tumoral endplate (EP) disruption in the risk of VCF and attempt to incorporate it into a simple risk stratification system.

METHODS:
This study was a retrospective cohort study from a single institution. Demographic and treatment information was collected for patients who received spinal SBRT between 2013 and 2019. EP disruption was noted on pre-SBRT computed tomography scan. The primary end point of 1-year cumulative incidence of VCF was assessed on follow-up MRI and computed tomography scans at 3-month intervals after treatment.

RESULTS:
A total of 111 patients were included. The median follow-up was 18 months. Approximately 48 patients (43%) had at least one EP disruption. Twenty patients (18%) experienced a VCF at a median of 5.2 months from SBRT. Patients with at least one EP disruption were more likely to experience VCF than those with no EP disruption (29% vs 6%, P < .001). A nomogram was created using the variables of EP disruption, a SINS of ≥7, and adverse histology. Patients were stratified into groups at low and high risk of VCF, which were associated with 2% and 38% risk of VCF (P < .001).

CONCLUSION:
EP disruption is a novel risk factor for VCF in patients who will undergo spinal SBRT. A simple nomogram incorporating EP disruption, adverse histology, and SINS score is effective for quickly assessing risk of VCF. These data require validation in prospective studies and could be helpful in counseling patients regarding VCF risk and referring for prophylactic interventions in high-risk populations.
Impact of drainage catheter material, size, and anti-dislodgement mechanism on percutaneous nephrostomy exchange intervals: a systematic review protocol
Authors: Iyer Deepak , Konstantinidis Menelaos , Li Hanzhou , Bercu Zachary , Moon John 
Published: October 2023

Background: Percutaneous nephrostomy (PCN) is a commonly performed procedure by interventional radiology and urology to treat urinary obstruction. In this procedure, a catheter is percutaneously placed into the renal pelvis for urinary diversion or hemorrhagic cystitis. Material type, catheter size, and catheter shape (anti-dislodgement feature) ultimately contribute to the inherent traits of longevity in drainage catheter device. Reviewing the relative strengths or weaknesses of products in the existing clinical market may help clinicians critically appraise the devices they use with evidence-based findings from this review. Furthermore, a deeper understanding of the relative strengths and weaknesses of existing devices may help inform the next generation of drainage catheter devices to prolong the interval between exchanges without detriment to patient safety. Methods: The following electronic databases will be queried: PubMed, Web of Science, Cochrane from their inception to January 2023 to identify randomized controlled trials (RCTs) and cohort studies to investigate the differences that our interventions of catheter material, size, and dislodgement mechanism will have on the exchange interval (standard of care 90 days vs. 60 days vs. 45 days vs. 30 days). The primary outcomes will be the drainage catheter exchange frequency. Ethics and dissemination: We aim to share our findings through high-impact peer reviewed journals. As drainage catheters and minimally invasive interventional radiology procedures become more popular, it is important for healthcare providers taking case of these populations to understand which variables might optimize patient care and minimize emergent exchanges. Data will be made available to readers. Registration: PROSPERO (CRD42023432788, 16 June 2023).
Application of Zoning Method in Assessing the Tourism and Recreational Potential of Rural Areas of Novosibirsk Region
Authors: Mytareva E. , Shamray I. , Elovskaya M. , Chernyh S. 
Published: October 2023

The article deals with the methodology of assessing the development of rural tourism in the region based on the application of the zoning method. The article is devoted to the study of key problems of rural tourism development in modern realities, taking into account the existing limitations and outlines the prospects for the implementation of this type of tourism in the Novosibirsk region. The authors critically analyze the scientific works of domestic scientists devoted to the development of agrarian (rural) tourism.
In the process of research, the author’s method of assessment of tourist and recreational potential of the Novosibirsk region was developed, criteria for calculating the potential of priority components of the tourist infrastructure were selected, the opportunities for the development of agrarian (rural) tourism were assessed with the selection of the most promising administrative-territorial (municipal) districts of the Novosibirsk region. The article is intended for managers of tourist business, students, any interested users.
Analysis of Real-Time Order Fulfillment Policies: When to Dispatch a Batch?
Authors: Gautam Natarajan , Geunes Joseph 
Published: October 2023

This paper considers orders that arrive one-by-one over time to a fulfillment center. Each order requests a product with some degree of customization that needs to be delivered expeditiously to a nearby location using a delivery vehicle. However, each vehicle can batch multiple orders together for delivery within a single trip. The benefits of batching include more efficient capacity utilization, lower total vehicle ownership requirements, and reduced environmental impact. The main drawback of batching is the consequent reduced average quality of service due to associated delivery delays when waiting for additional orders to arrive and executing a delivery route. To address this trade-off, we consider a set of threshold policies for batching and dispatching groups of orders, and characterize the associated long-run average cost per unit time for each policy that explicitly accounts for the customer’s total order lead time, including the time between order dispatch and delivery to the customer which, in turn, depends on route sequencing policies. For the threshold policies, our state variable may not only include the number of outstanding orders, but may also incorporate information on order arrival times and delivery locations. We model the stochastic dynamics of the system and obtain the long-run average cost per unit time, which we compute using a renewal-reward approach. We also consider different delivery sequencing approaches, including first-come, first-served and shortest traveling salesperson. In addition, we evaluate the effectiveness of accounting for all order information in the decision-making process, as opposed to just the number of outstanding orders or the time in the system for each order. Our analysis shows that a generalized class of cost- and quantity-based threshold policies often outperforms existing policies in the literature with the additional benefits of being robust to overestimates of the optimal cost threshold value and achieving strong delay cost performance. History: This paper has been accepted for the Service Science/Stochastic Systems Joint Special Issue. Supplemental Material: The online appendix is available at https://doi.org/10.1287/serv.2022.0042 .
Acute respiratory distress syndrome due to monkeypox virus
Authors: Tchoubou Tona , El-Hosni Rima , Dollat Marion , Jaquet Pierre , Tournus Celine , Tandjaoui-Lambiotte Yacine , Da Silva Daniel 
Published: October 2023

We report the first case of monkeypox virus (MPXV) associated acute respiratory distress syndrome (ARDS). A 34-year-old French woman with no medical history was admitted to the intensive care unit (ICU) for fever, altered mental status, hypotension and hypoxaemia. She presented with a diffuse skin rash with vesiculopustular lesions involving the four limbs and perineal ulcers with a skin swab positive for MPXV. On day 2, the patient presented moderate ARDS requiring invasive mechanical ventilation. She also had pleural empyema due to Streptococcus pyogenes. MPXV PCR was positive in the bronchoalveolar lavage, the pleural effusion and the blood. The patient was treated with tecovirimat. Despite the treatment, she had persistent viraemia for at least ten days. The patient condition rapidly improved; she was weaned from mechanical ventilation on day 18 despite the persistence of radiological lung opacities. She fully recovered and was discharged home on day 38 after admission.
The effect of circular stapler size on anastomotic stricture formation in colorectal surgery: A propensity score matched study
Authors: Lee Kil-yong , Lee Jaeim , Park Youn Young , Kim Hyung-Jin , Oh Seong Taek 
Published: October 2023

Background
Small circular staplers possess the advantage of being relatively easy to use when compared to larger circular staplers. However, there is some contention as to whether the use of small circular staples in colorectal surgery increases the incidence of anastomotic strictures. This study aimed to determine whether the frequency of anastomosis site stricture formation differs depending on stapler size when performing anastomosis in colorectal surgery.

Methods
Patients who underwent surgery for colon or rectal disease between June 1, 2009, and December 31, 2021, and who had circular staplers used for the formation of intestinal anastomoses post colectomy were included in our study. Propensity score matching with a 1:1 ratio using logistic regression was performed. The primary outcome was the anastomotic stricture rate, and the secondary outcome was total anastomotic complications.

Results
A total of 875 patients who were operated on by surgeons using 28/29-mm and 25-mm circular staplers were included. After propensity score matching, 106 patients were assigned to each group. Anastomotic strictures occurred in two cases (1.9%) from the 25-mm group and in four cases (3.8%) from the 28/29-mm group. There were no statistically significant differences between the two groups (p = 0.683). Anastomotic complications were observed in two cases (1.9%) from the 25-mm group and in six cases (5.7%) from the 28/29-mm group; no statistically significant differences were found (p = 0.280).

Conclusion
Circular stapler size does not influence anastomotic stricture formation in colorectal surgery.
Is parenthood associated with self-rated health among women in Brazil?
Authors: Ferreira Matheus Souza , da Silva Zilda Pereira , de Almeida Marcia Furquim , Alencar Gizelton Pereira 
Published: October 2023

Background
Previous studies conducted in Europe and North America addressing the relationship between self-rated health and parenthood offer inconsistent results, with effects ranging from nonsignificant to significant and in opposite directions. The aim of the present study was to explore the relationship between parenthood and self-rated health (SRH) among women in Brazil (a country with strong inequalities) considering the time interval from the last delivery in the analyses, as proposed in previous studies set in Sweden.

Methods
The study used data from cross-sectional National Health Surveys in Brazil conducted from 2013 to 2014 and 2019 to 2020 with selected groups of 20,046 and 25,100 women for whom complete data were available on the variables of interest. The primary outcome was self-rated health measured on a five-point scale. Partial proportional odds models were employed.

Results
Compared to women that were not a parent, primiparous women whose delivery was within less than one year had a lower likelihood of worse SRH (OR (95% CI): 0.58–0.84 in 2013, and 0.64–0.94 in 2019), whereas multiparous women whose last delivery was more than one year earlier had greater likelihood of worse SRH (OR (95% CI): 1.08–1.27 in 2013, and 1.21–1.39 in 2019).

Conclusions
An association was found between parenthood and SRH among Brazilian women. Considering the epidemiological relevance of SRH, different aspects of parenthood concerning parity and time since the last delivery should be considered in further analyses.
Prevalence and determinants of malaria infection among pregnant women attending antenatal clinic in Ejisu government hospital in Ghana: A cross-sectional study
Authors: Dwumfour Catherine Kroamah , Bam Victoria Bubunyo , Owusu Lydia Boampong , Poku Collins Atta , Kpabitey Rhoda Dewe , Aboagye Priscilla , Ibrahim Amshariatu Suntaa 
Published: October 2023

Introduction
Malaria in pregnancy is a global public health problem with the majority of its impact seen in sub-Saharan Africa. Pregnant women with malaria infection are at risk of adverse maternal outcomes. In Ghana, malaria in pregnancy accounts for about 17.6% of outpatient department attendance. Ashanti region is among the three regions with the highest malaria prevalence in pregnancy, particularly in the Ejisu Municipality. The study, therefore, assessed the prevalence and determinants of malaria infection among pregnant women seeking antenatal care at the Ejisu Government Hospital in Ghana.

Methods
A cross-sectional study design with a convenience sampling technique was used to select 140 respondents for the study. Primary data such as age and residence of respondents were collected using a questionnaire and secondary data such as gestational age and Sulphadoxine Pyrimethamine (SP) administration were collected from clients’ maternal health record booklet. Bivariate and multivariate logistic regression analysis were used to assess the association between the malaria infection and the independent variables, and a p-value of < 0.05 was considered statistically significant.

Results
The overall prevalence of malaria in pregnancy was 24 (17.1%). Most of the respondents had received counselling and health education 126 (90%), two or more doses of SP 95 (87.2%), Insecticide Treated Net (ITN) 99 (70.7%) and were sleeping under ITN 104 (74.3%). Multivariate logistic regression analysis showed a statistically significant association between malaria infection and sleeping under ITN (AOR = 0.05; 95% CI = 0.01–0.28, p< .001), the use of insecticide mosquito spray (AOR = 0.27; 95% CI = 0.09–0.84, p = .045) and reason for not using ITN due to the use of other preventive measures (AOR = 0.06; 95% CI = 0.01–0.61, p = .017).

Conclusion
There was a high prevalence of malaria infection among study respondents despite the high usage of preventive measures for malaria in this study. It is therefore crucial that stakeholders in malaria control identify effective strategies to curb malaria transmission globally.