bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence and the factors associated with microalbuminuria among patients with type 2 diabetes mellitus and/or hypertension in the urban areas of Puducherry district: a cross-sectional study
Authors: Sivanantham Parthibane , Sahoo Jaya Prakash , Lakshminarayanan Subitha , Bobby Zachariah , Loganathan Vignesh , Kar Sitanshu Sekhar 
Published: January 2024

Abstract

Background
Microalbuminuria is an early indicator for renal and cardiovascular diseases, especially among patients with diabetes mellitus (DM) and hypertension (HTN). We determined the prevalence and the factors associated with microalbuminuria among patients with type 2 DM and/or HTN in the urban areas of the Puducherry district in India.

Methods
We included 225 patients aged 40–69 years with DM and/or HTN from a non-communicable diseases (NCDs) survey conducted during 2019–2020 in the urban areas of Puducherry district. The prevalence of microalbuminuria and various biological risk factors of NCDs were assessed as per the WHO STEPS methodology. The prevalence of microalbuminuria was presented as proportions (95% CI), and the adjusted prevalence ratio (aPR) was estimated using weighted forward stepwise generalized linear modelling. P-value ≤0.05 was considered statistically significant.

Results
The mean (SD) age of the patients was 54 (11) years. Over one-third (38.2%) (95% CI: 31.6–44.4) of patients with DM and/or HTN had microalbuminuria. The prevalence was highest among those having both DM and HTN 48% (95% CI: 37–59), followed by those having only DM 40.6% (95% CI: 29–52.2) and only HTN 27.7% (95% CI: 18.1–38.6). The prevalence of microalbuminuria was twice (aPR = 2.1, 95% CI: 1.1–3.9) higher among women and 2.4 times (95% CI: 1.12–5.1) higher among those having both DM and HTN as compared to those with only HTN.

Conclusion
The prevalence of microalbuminuria among patients with DM and/or HTN is concerningly high. Population-based screening for microalbuminuria, especially among women and those having both DM and HTN, needs to be undertaken in the urban areas of Puducherry district.
A fast algorithm to factorize high-dimensional tensor product matrices used in genetic models
Authors: Lopez-Cruz Marco , Pérez-Rodríguez Paulino , de los Campos Gustavo 
Published: January 2024

Abstract
Many genetic models (including models for epistatic effects as well as genetic-by-environment) involve covariance structures that are Hadamard products of lower rank matrices. Implementing these models requires factorizing large Hadamard product matrices. The available algorithms for factorization do not scale well for big data, making the use of some of these models not feasible with large sample sizes. Here, based on properties of Hadamard products and (related) Kronecker products, we propose an algorithm that produces an approximate decomposition that is orders of magnitude faster than the standard eigenvalue decomposition. In this article, we describe the algorithm, show how it can be used to factorize large Hadamard product matrices, present benchmarks, and illustrate the use of the method by presenting an analysis of data from the northern testing locations of the G × E project from the Genomes to Fields Initiative (n ∼ 60,000). We implemented the proposed algorithm in the open-source “tensorEVD” R package.
Of Geographical Indications and Wars: What the Specifications Tell Us about the Impact of Military Conflicts on French Protected Designations of Origin
Authors: Kyrylenko Anastasiia 
Published: January 2024

Abstract
Historical developments such as wars significantly impact geographical indications (GIs) and their terroir. Wars can destroy vineyards, dismantle production tools or deprive agriculture of its workforce by mobilising civilians. However, academic literature often approaches the impact of wars on GIs as anecdotal evidence rather than an object of study. This article aims to fill this research gap by examining the impact of World War I (WW1) and World War II (WW2) on French protected designations of origin (PDOs). This is done by applying quantitative and qualitative research methods to the specifications of all French PDOs that were registered in the European Union as of 23 November 2022. A total of 43 PDOs affected either by WW1, by WW2, or by both were identified. While the research understandably identifies mostly negative impacts (e.g., manpower shortage or production decline), one unexpected finding is that wars also had a positive impact on some French PDOs, including an increase in consumption and a growth in reputation beyond the original region of production.
Anti-corruption measures in large-scale construction projects
Authors: Nezami Pardis Nikoonam , Shojaei Payam , Ebrahimi Aboalghasem 
Published: January 2024

Abstract
Accepted by: Konstantinos Nikolopoulos
Corruption is affecting many developing countries, manifested often in construction projects. This study identifies the factors causing corruption and prioritizes anti-corruption measures in large-scale urban construction projects with empirical data from a developing country: Iran. The model consists of six main dimensions including 24 measures and was developed by systematically reviewing the literature as well as collecting primary data through interviewing experts. The model prioritizes the anti-corruption measures through an integrated method of the fuzzy best-worst method and fuzzy measurement alternatives and ranking according to the compromise solution. The field of corruption has a multi-faceted nature and inherent uncertainty, which necessitates this integrated approach for its analysis. The results reveal that the ‘lawlessness and deregulation in public construction projects’ and ‘top management and leader commitment’ are the most important causes of corruption. This study offers two main contributions. First, it develops a conceptual model to evaluate and prioritize anti-corruption measures; second, it generates practical solution for reducing corruption in municipal and urban management, thus enhancing the prospects of successful construction projects in developing countries.
A phylogenomic monograph of West-Palearctic Nomada (Hymenoptera: Apidae)
Authors: Straka Jakub , Benda Daniel , Policarová Jana , Astapenková Alena , Wood Thomas J , Bossert Silas 
Published: January 2024

Abstract
We reconstruct the phylogeny of the most speciose genus of cuckoo bees, genus Nomada Scopoli, 1770, using 221 species from throughout its distribution, yet with a strong emphasis on the West Palearctic. For phylogenetic reconstruction, we sequenced ultraconserved elements, allowing robust phylogenetic estimates with both concatenation and coalescent-based methods. By integrating extensive information on Nomada host records, we study macroevolutionary patterns of host associations, transitions, and phylogenetic conservatism. Using Bayesian divergence time estimates, we assess the historical biogeography of the genus, focusing on the West Palearctic. Our results show that Nomada likely originated in the Eastern Mediterranean and Near Eastern region, and likely expanded its range to a near-global distribution from there. We recovered long-standing phylogenetic conservatism in the host usage of Nomada and provided strong statistical evidence for an ancestral host association with Andrena and its most recent common ancestor. However, host transitions occurred multiple times independently in the natural history of Nomada, and species of the genus are brood parasites in at least 5 genera and 4 different families of bees in the Old World. At last, we systematically revise the taxonomy of the Old World Nomada by integrating morphological study with our well-supported phylogenetic estimates. We re-establish the genus Acanthonomada Schwarz, 1966, stat. res., as a distinct, second genus in the tribe Nomadini. We recognize 13 subgenera for Nomada, 9 of which are described as new: Afronomada Straka and Bossert, subgen. nov., Colliculla Straka, subgen. nov., Gestamen Straka, subgen. nov., Hungias Straka, subgen. nov., Mininomada Straka, subgen. nov., Nomacolla Straka, subgen. nov., Nomonosa Straka, subgen. nov., Plumada Straka, subgen. nov., and Profuga Straka, subgen. nov. Aside from the subgenus Nomada s.s., we reinstitute 3 previously synonymized subgenera: Heminomada Cockerell, 1902, stat. res., Holonomada Robertson, 1903, stat. res., and Hypochrotaenia Holmberg, 1886 stat. res. A total of 15 subgeneric names are formally synonymized with the newly established subgeneric concepts.
The Use of Intraosseous Infusion in the Early Resuscitation of Patients With Extremely Severe Burns
Authors: Wang Yuwei , Zhou Shuaishuai , Wang Lizhu , Fang Jue , Zhang Yukun , Shi Lili , Lin Gaoxing , Zhang Mangwei , Wang Sa 
Published: January 2024

Abstract
According to research, shock, the most common complication of extremely severe burns, is also the leading cause of mortality among patients with such burns. The case fatality rate reaches 83.45% when the total burn area exceeds 90%. The American Heart Association in 2020 recommended the intraosseous (IO) access after the peripheral access and prior to the central venous access when venous cannulation is either difficult or delayed. The use and experience with intraosseous infusion in extremely severe burns are still limited. We report efficacy and safety results from 19 burn patients treated with IO infusion between June 2020 and December 2022. In these patients, the mean injury time of burns was 1.55 ± 1.10 hours, the mean burn surface area was 86.24% ± 11.33%, the mean catheterization time was 49.68 ± 10.11 seconds, and the mean emergency retention time was 2.75 ± 1.74 hours, the mean actual fluid supplement amount was 5,533.68 ± 3,077.19 mL, the mean hourly urine volume of the patient was 93.31 ± 60.94 mL, the mean emergency detention time was 4.16 ± 2.97 hours, and the mean duration of hospitalization was 34.50 ± 25.38 days. The results demonstrated a clinically meaningful improvement and higher response rate vs peripheral venous cannulation and an acceptable safety profile in those patients.
The Dot: Statistics, Society, and Graphic Design, c. 1830–1970
Authors: Pivo Hannah 
Published: January 2024

Abstract
This article takes Chermayeff & Geismar Associates’ cover designs for a paperback reprint series, “Studies in American Negro Life” (1968–c. 1972), as a starting point for investigating the history of the dot as a tool for social-statistical visualization. It first situates the series—which re-issued texts on Black history, sociology, and literature—within the context of 1960s urban unrest in the United States and shows how the arrangements of dots on each cover relate to contemporaneous experiments in urban cartography. It then traces a longer genealogy, considering the dot in relation to the 19th-century emergence of “society” and “the social” as novel epistemic concepts that came to serve as the primary objects of study for the modern social sciences in the 20th century. I address the integral role of statistics in this history, demonstrating how the logic of aggregation that undergirds statistical thinking has been habitually visualized through the dot. The article concludes by returning to the book series, addressing some of the individual covers and arguing that by evoking the visual vocabulary of the social sciences, the cover designs frame the series as a social scientific project overall.
Modified Ludloff’s medial approach for resection of heterotopic ossification of the hip following severe SARS-CoV-2 infection: a case report
Authors: Ramón Ricardo , Holguín Esteban , Ribas Manuel , Al Hussin Nihad , Ezechieli Marco 
Published: January 2024

ABSTRACT
The coronavirus disease 2019 pandemic has significantly affected people worldwide. Herein, we present a case of massive heterotopic ossification (HO) of the right hip following severe SARS-CoV-2 infection. The exact origin of HO development is still unknown, but a critical illness, chronic immobilization and hypoxia are important risk factors. Considering the location and size of the HOs in this case, modified Ludloff’s medial approach of the hip was used. This approach allows for good exposure and access to the medial and inferior part of the hip joint and the successful extirpation of the pathologic tissue.
The Making of Balance-of-Power—Power Asymmetry, Domestic Politics, and the Making of Balancing Practices
Authors: Vadai Einat , Press-Barnathan Galia 
Published: January 2024

AbstractThis article joins the growing body of literature that perceives balance of power as a social construct containing shared understandings that comprise states’ repertoire of balancing practices. Distinct repertoires of balancing have prevailed in different international orders. We build on this work and focus on a less explored, though important, political process to explain the variation in balancing practices over time. We suggest that external threats, domestic considerations of key states, and diffusion mechanisms deriving from hierarchical relations can explain the evolution of balancing practices. More specifically, we suggest that balancing practices evolve in the domestic arena of the dominant state at a given time, as leaders frame their foreign policy in terms that most closely resonate with their domestic circumstances. Secondary states, who depend on the dominant state for their security, will tend to adopt its balancing practice. They will do so because the hierarchy of the international system enables the dominant state to use positive and negative leverage tools to pressure them, or because they voluntarily calculate that this choice will enhance their security. To demonstrate the importance of studying the social construction of balancing practices and the impact of dominant states on the content of these practices, we examine two central case studies of different balancing practices—the rise of early eighteenth-century Britain and the emergence of the logic of a contrived balance of power, and the rise of American hegemony in the aftermath of World War II that generated the practice of ideological balancing
Weakened relationship between tree growth and nitrogen availability due to global CO2 increase and warming in the Taibai Mountain timberline, central China
Authors: Yin Lelong , Liu Xiaohong , Zeng Xiaomin , Wang Ziyi , Xu Guobao , Zhao Liangju , Lu Qiangqiang , Zhang Lingnan , Xing Xiaoyu 
Published: January 2024

Abstract
Climate warming, rising atmospheric CO2 concentration (Ca), and nitrogen (N) availability are exerting profound impacts on global forest ecosystems, particularly in high-altitude mountains. This study investigated the tree-growth dynamics of timberline Larix chinensis in the Taibai Mountain, central China, and explored its ecophysiological responses to environmental stresses by combining tree growth and stable isotopes. The results showed that the growth rate of L. chinensis has significantly increased since the 1960s, and that tree growth in this timberline was particularly sensitive to temperature in spring. Moreover, the continuously rising intrinsic water-use efficiency (iWUE), linked to higher Ca and warmer environment, promoted the growth of L. chinensis. Before the 1960s, tree-ring δ15N gradually increased, then shifted to an insignificant decline with the acceleration of tree growth, and broke the preexisting carbon–nitrogen balance. Meanwhile, climate warming and increased iWUE have replaced N as the principal drivers of tree growth since the 1960s. It is believed that L. chinensis may gradually suffer a decline in N availability as it continues to grow rapidly. The insightful understanding of the biochemical mechanisms of plant responses to growth-related environmental conditions will improve our ability to predict the evolution of high-elevation mountain ecosystems in the future.
Identifying the intersegmental plane for segmentectomy using the open insufflation technique
Authors: Dai Wei , Mei Na , Ning Ye , Zhang Wentian , Li Yan , Jiang Lei 
Published: January 2024

Abstract
Accurate identification of the intersegmental plane is the key to successful segmentectomy. This case series included 41 patients who underwent uniportal thoracoscopic segmentectomy using the open insufflation method to identify the intersegmental plane for pulmonary nodules. The median age of the patients was 58 (range 35–73) years, and 63.4% were female. Malignant pulmonary nodules accounted for 80.5% of cases and were staged as 0–IA2. Seventeen patients underwent a single subsegmentectomy or single segmentectomy, and 24 underwent combined subsegmentectomy or subsegmentectomy combined with segmentectomy. There was no conversion to multiportal video-assisted thoracoscopic surgery, open surgery, or lobectomy. The median operative time was 84 (range 45–194) min, and the median blood loss was 50 (range 10–150) ml. The median chest tube duration and postoperative hospital stay were 2 (range 1 − 7) days. One (2.4%) developed an air leak for &gt;5 days. No deaths occurred within 30 days after surgery.
Resection of a pure androgen secreting adrenal adenoma in a postmenopausal woman: a case report
Authors: Dalal Ahmad , Dwayat Abdallah , Khamashta Natalie , Alashwas Mo’men , Asi Tariq 
Published: January 2024

Abstract
Pure androgen secreting adrenal tumors are exceedingly rare, presenting in higher numbers in women compared with men, and are particularly rare in women of postmenopausal age. Postmenopausal hyperandrogenism is usually ovarian or adrenal in origin, with tumors representing an uncommon cause, which are more frequently ovarian but could also be adrenal. Herein we present a case of a 61-year-old postmenopausal woman, who had suffered multiple reproductive disturbances, presenting with a 10-year history of virilizing symptoms, most bothersome of which was generalized hirsutism, alongside clitoromegaly, irritability, and voice deepening. Work-up of the patient revealed a 1.5 cm left adrenal mass, which was removed through laparoscopic total adrenalectomy. Postoperatively, the patient’s androgen levels dropped significantly. An adrenal androgen secreting tumor is a can't miss diagnosis that should always be considered in the evaluation of postmenopausal women with hyperandrogenism, alongside the more common etiologies. Regular hormonal follow-up is essential.
Evidence for decreased copper associated with demyelination in the corpus callosum of cuprizone-treated mice
Authors: Hilton James B W , Kysenius Kai , Liddell Jeffrey R , Mercer Stephen W , Hare Dominic J , Buncic Gojko , Paul Bence , Wang YouJia , Murray Simon S , Kilpatrick Trevor J , White Anthony R , Donnelly Paul S , Crouch Peter J 
Published: January 2024

Abstract
Demyelination within the central nervous system (CNS) is a significant feature of debilitating neurological diseases such as multiple sclerosis and administering the copper-selective chelatorcuprizone to mice is widely used to model demyelination in vivo. Conspicuous demyelination within the corpus callosum is generally attributed to cuprizone's ability to restrict copper availability in this vulnerable brain region. However, the small number of studies that have assessed copper in brain tissue from cuprizone-treated mice have produced seemingly conflicting outcomes, leaving the role of CNS copper availability in demyelination unresolved. Herein we describe our assessment of copper concentrations in brain samples from mice treated with cuprizone for 40 d. Importantly, we applied an inductively coupled plasma mass spectrometry methodology that enabled assessment of copper partitioned into soluble and insoluble fractions within distinct brain regions, including the corpus callosum. Our results show that cuprizone-induced demyelination in the corpus callosum was associated with decreased soluble copper in this brain region. Insoluble copper in the corpus callosum was unaffected, as were pools of soluble and insoluble copper in other brain regions. Treatment with the blood–brain barrier permeant copper compound CuII(atsm) increased brain copper levels and this was most pronounced in the soluble fraction of the corpus callosum. This effect was associated with significant mitigation of cuprizone-induced demyelination. These results provide support for the involvement of decreased CNS copper availability in demyelination in the cuprizone model. Relevance to human demyelinating disease is discussed.
RT-PCR assay to detect FGFR3::TACC3 fusions in formalin-fixed, paraffin-embedded glioblastoma samples
Authors: Priesterbach-Ackley Loudy P , van Kuik Joyce , Tops Bastiaan B J , Lasorella Anna , Iavarone Antonio , van Hecke Wim , Robe Pierre A , Wesseling Pieter , de Leng Wendy W J 
Published: January 2024

Abstract

Background
One targeted treatment option for isocitrate dehydrogenase (IDH)-wild-type glioblastoma focuses on tumors with fibroblast growth factor receptor 3::transforming acidic coiled-coil-containing protein 3 (FGFR3::TACC3) fusions. FGFR3::TACC3 fusion detection can be challenging, as targeted RNA next-generation sequencing (NGS) is not routinely performed, and immunohistochemistry is an imperfect surrogate marker. Fusion status can be determined using reverse transcription polymerase chain reaction (RT-PCR) on fresh frozen (FF) material, but sometimes only formalin-fixed, paraffin-embedded (FFPE) tissue is available.

Aim
To develop an RT-PCR assay to determine FGFR3::TACC3 status in FFPE glioblastoma samples.

Methods
Twelve tissue microarrays with 353 historical glioblastoma samples were immunohistochemically stained for FGFR3. Samples with overexpression of FGFR3 (n = 13) were subjected to FGFR3::TACC3 RT-PCR on FFPE, using 5 primer sets for the detection of 5 common fusion variants. Fusion-negative samples were additionally analyzed with NGS (n = 6), FGFR3 Fluorescence In Situ Hybridization (n = 6), and RNA sequencing (n = 5).

Results
Using RT-PCR on FFPE material of the 13 samples with FGFR3 overexpression, we detected an FGFR3::TACC3 fusion in 7 samples, covering 3 different fusion variants. For 5 of these FF was available, and the presence of the fusion was confirmed through RT-PCR on FF. With RNA sequencing, 1 additional sample was found to harbor an FGFR3::TACC3 fusion (variant not covered by current RT-PCR for FFPE). The frequency of FGFR3::TACC3 fusion in this cohort was 9/353 (2.5%).

Conclusions
RT-PCR for FGFR3::TACC3 fusions can successfully be performed on FFPE material, with a specificity of 100% and (due to limited primer sets) a sensitivity of 83.3%. This assay allows for the identification of potential targeted treatment options when only formalin-fixed tissue is available.
ARPES investigation of the electronic structure and its evolution in magnetic topological insulator MnBi2+2nTe4+3n family
Authors: Xu Runzhe , Xu Lixuan , Liu Zhongkai , Yang Lexian , Chen Yulin 
Published: January 2024

ABSTRACT
In the past 5 years, there has been significant research interest in the intrinsic magnetic topological insulator family compounds MnBi2+2nTe4+3n (where n = 0, 1, 2 …). In particular, exfoliated thin films of MnBi2Te4 have led to numerous experimental breakthroughs, such as the quantum anomalous Hall effect, axion insulator phase and high-Chern number quantum Hall effect without Landau levels. However, despite extensive efforts, the energy gap of the topological surface states due to exchange magnetic coupling, which is a key feature of the characteristic band structure of the system, remains experimentally elusive. The electronic structure measured by using angle-resolved photoemission (ARPES) shows significant deviation from ab initio prediction and scanning tunneling spectroscopy measurements, making it challenging to understand the transport results based on the electronic structure. This paper reviews the measurements of the band structure of MnBi2+2nTe4+3n magnetic topological insulators using ARPES, focusing on the evolution of their electronic structures with temperature, surface and bulk doping and film thickness. The aim of the review is to construct a unified picture of the electronic structure of MnBi2+2nTe4+3n compounds and explore possible control of their topological properties.