bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of delayed-release antibiotics on the rate of postoperative wound infection for implanted neuromodulatory devices
Authors: Cleary Daniel R. , Palan Mihir J. , Useinovic Nemanja , Burchiel Kim J. 
Published: February 2025

OBJECTIVE
Implanted neuromodulatory devices are important for the surgical management of pain, epilepsy, movement disorders, and spasticity. These devices are surgically implanted, but many must be periodically explanted and replaced as batteries deplete or devices fail. Replacement surgery risks further infections that require device explantation, incur large financial costs, and reduce patient quality of life. To reduce infection rates, a single surgeon began using vancomycin-impregnated absorbable calcium sulfate delayed-response beads with neuromodulatory device and intrathecal pump primary implantations and replacements. The infection rates when using vancomycin-impregnated beads were compared with previously published rates from the same surgeon.

METHODS
Patients were identified who underwent primary placement or replacement of an implanted neuromodulatory control device (pumps, generators, and stimulators) with vancomycin-impregnated absorbable calcium sulfate beads between 2019 and 2022. Control data were obtained from patients who underwent surgery prior to the start of using antibiotic beads (2016–2019). Postoperative infection status as well as de-identified demographic and clinical data were extracted from electronic health records. Patients were stratified by use of antibiotic beads, device type, and whether they had an infection within 1 year requiring explantation. Statistical comparisons were made using independent t-tests, Fisher’s exact test, and the chi-square test, with α set at 0.05. Effect size was calculated using Cohen’s h statistic.

RESULTS
A total of 665 surgeries were included for 611 patients who received antibiotic beads with device implantation, compared to 393 surgeries for 379 patients without antibiotic beads. The postoperative wound infection rate was 1.5% (n = 10 patients) versus 3.6% (n = 14 patients) for antibiotic beads versus controls (p = 0.03). When stratified by device type, a significant reduction in infection rate was found only with deep brain stimulation (DBS) generators (3.4% for controls vs 0.2% for beads, p = 0.002), which corresponds to a small to medium effect size (h = 0.27).

CONCLUSIONS
The use of vancomycin-impregnated absorbable calcium sulfate beads was associated with a reduced rate of postoperative infection rates with implantable devices, and specifically for DBS primary implantation and replacement surgeries.
Implementation of Integrated Hybrid PLTS Lathe Machines in UMKM Processing Wood-Based Crafts
Authors: Alia* Nila , Widjanarko Widjanarko , Perdana Fengky Adie , Udianto Pondi , Adiwidodo Satworo , Puspitasari Etik , Viyus Vinan 
Published: February 2025

Community service activities have a central role in supporting sustainable economic growth, especially in the Micro, Small and Medium Enterprises (UMKM) sector. UMKM processing wood-based crafts, as an integral part of local cultural diversity, face significant energy challenges in sustainable development. In order to overcome this obstacle, this community service activity focuses on implementing a Hybrid Solar Power Plant (PLTS) that is integrated with a lathe for UMKM processing wood-based crafts. The purpose of this community service activity is to provide sustainable solutions for UMKM in terms of reliable energy, while supporting the development of environmentally friendly technologies. The methodology applied includes an initial survey of energy needs, design and installation of the Hybrid PLTS system, lathe operator training, and continuous performance monitoring. This activity involves collaboration with UMKM owners and the local village government to ensure the implementation of solutions that are relevant to real needs and conditions. The results of this activity show that the implementation of Hybrid PLTS integrated with lathes has a significant positive impact on production efficiency and product quality for UMKM. These activities make a real contribution to sustainable economic development at the local level. The results can be used as a model for similar developments in other UMKM sectors.
Keywords: Community Service, Hybrid PLTS, UMKM, Processing of Wood-Based Crafts, Sustainable Energy, Renewable Energy
Analisis Pemasaran Ikan Konsumsi Keramba Jaring Apung Waduk Jatiluhur Zona 1, Kecamatan Purwakarta, Kabupaten Purwakarta
Authors: Fajrin Audy Husnandina  , Atikah Nurhayati  , Asep Agus Handaka Suryana  , Ine Maulina  
Published: February 2025

Kabupaten Purwakarta memiliki hasil produksi perikanan budidaya mencapai 94,5 ribu ton hanya dari hasil budidaya Keramba Jaring Apung (KJA) sehingga menjadi daerah dengan produksi budidaya tertinggi di Jawa Barat. Salah satu yang berpotensi tinggi untuk menghasilkan produksi budidaya ikan konsumsi yang melimpah adalah Waduk Jatiluhur. Namun, hasil produksi budidaya ikan konsumsi yang melimpah di Waduk Jatiluhur akan mengalami kerugian apabila tidak disertai dengan proses pemasaran yang cepat dan tepat. Penelitian ini dilaksanakan di Waduk Jatiluhur zona 1, Kecamatan Purwakarta, Kabupaten Purwakarta dengan waktu riset dari bulan Oktober 2023 – Februari 2024. Tujuan penelitian ini yaitu untuk menganalisis pola saluran pemasaran, biaya pemasaran, keuntungan, margin, farmer's share, benefit cost ratio dan efisiensi pemasaran dari ikan konsumsi yang dibudidayakan dengan sistem budidaya KJA di Waduk Jatiluhur zona 1. Pengambilan sampel dalam penelitian ini menggunakan metode purposive sampling dan snowball sampling, sementara itu data dianalisis menggunakan metode deskriptif kualitatif dan kuantitatif. Hasil dari penelitian ini yaitu saluran pemasaran ikan konsumsi terbagi menjadi tiga dengan saluran pemasaran III yang paling efisien, pemasaran ikan mas lebih efisien dibandingkan ikan nila serta usaha pemasaran ikan konsumsi dapat dikatakan layak untuk dijalankan karena memperoleh nilai rata-rata BCR >1.
Efektivitas Tepung Daun Mangrove untuk Mengendalikan Penyakit Vibriosis pada Larva Udang Vaname (Litopenaeus vannamei)
Authors: Arifah Sitti , Amrullah  , Wahidah  , Ardiansyah  , Khatimah Khusnul 
Published: February 2025

Shrimp production in several Asian countries, including Indonesia, accounts for more than 85% of world production, thus control of shrimp larval diseases must be strengthened to increase production. This study aimed to test the effectiveness of mangrove leaves, Rhizopora sp, in controlling larval vibriosis of the vannamei shrimp (Litopenaeus vannamei). The study began with in vitro tests to evaluate the antimicrobial activity of mangrove leaf flour against Vibrio sp bacteria at doses of 400, 500, 600, 700, 800, 900, 1000 mg/L, 5% amoxicillin antibiotic (K+) and without mangrove flour (K). In the in vivo test, vannamei shrimp larvae (mysis-3) were immersed in a solution containing mangrove leaf flour with the three best doses of in vitro test results; 800, 900, and 1000 mg/L water, plus K-, for 15 minutes according to the treatment dose and maintained for 8 days before being challenged with Vibrio spp. The parameters observed were total hemocyte count (THC), differential hemocyte count (DHC), and survival rate (SR), which were observed on days 1 and 8, respectively, with the SR parameter observed on day 7 following the challenge test. The results showed that the Mangrove leaf diet at 800 and 900 mg/L significantly improved larval resistance to the pathogen V. harveyi (P < 0.05). The high resistance was triggered by THC immunological response and the high proportion of semi-granular and hyaline at doses of 800 and 900 mg/L (P<0.05). Mangrove leaf powder can therefore suppress vibriosis disease in vanamei shrimp larvae using the immersion method at 800 and 900 mg/L concentrations.
Deskripsi dan Karakteristik Morfometri Kambing Peranakan Etawa yang Terintegrasi dengan Tanaman Lada
Authors: Setiawan Duta 
Published: February 2025

Sistem integrasi ternak kambing peranakan Ettawah (PE) dan tanaman lada merupakan salah satu model pengembangan budidaya ternak kambing PE dalam meningkatkan efisiensi dan produktivitas usaha pertanian. Penelitian bertujuan mengetahui deskripsi karakteristik peternak dalam menerapkan integrasi kambing PE dan tanaman lada, kapasitas mengarit serta pengukuran morfometrik pada tubuh kambing PE di Kabupaten Bengkayang. Penelitian dilakukan di kecamatan Seluas Kabupaten Bengkayang dengan metode survei dan wawancara. Penentuan peternak secara purposive dengan kriteria kelompok ternak masih tetap melaksanakan usaha ternak kambing PE terintegrasi dengan tanaman lada. Analisis data karakteristik peternak dan morfometrik secara deskriptif dan untuk mengetahui hubungan antara kapasitas mengarit kambing PE integrasi dengan tanaman lada dengan satuan ternak (ST) dianalisis menggunakan regresi linear. Hasil penelitian menunjukkan deskripsi peternak kambing PE yang terintegrasi dengan tanaman lada yaitu berdasarkan umur masih pada usia produktif 41-50 tahun, dan pengalaman beternak kambing PE selama 11-20 tahun. Kapasitas mengarit peternak kambing PE sebesar 32.71 Kg dengan R2 sebesar 94.93 %. Morfometri Kambing PE jantan dan betina berusia sekitar 2 tahun yang terintegrasi dengan tanaman lada di Kecamatan Seluas tidak jauh berbeda dengan SNI 7352.1, sehingga masih baik untuk ditingkatkan performanya.
Pengembangan Potensi Lokal Ikan Tuna Sirip Kuning (Thunnus albacares) Menjadi Cemilan Sehat untuk Mencegah Stunting di Kota Sorong, Papua Barat Daya
Authors: Saif Sulfiana , Hardianti Fatimah , Muslimin Istyqamah , Marselina Ghela Maria , Kelibay Amirula , Tanasali Fadalia 
Published: February 2025

Berdasarkan hasil Survei Status Gizi Indonesia (SSGI), prevelensi stunting di Papua Barat tercatat sebesar 26,02% ditahun sebelumnya, naik menjadi 30,00% pada tahun 2022. Saat ini, sebagian besar anak kurang memperhatikan jenis makanan yang mereka makan, dan lebih sering mengkonsumsi cemilan yang kurang sehat. Tujuan dari penelitian ini yaitu 1) Mengembangkan produk stik ikan tuna sirip kuning menjadi produk cemilan sehat, dan 2) Mengetahui kandungan gizi dan tingkat kesukaan produk stik ikan tuna agar memenuhi keseimbangan nutrisi anak-anak untuk mencegah stunting. Perlakuan pada penelitian ini adalah penambahan tepung ikan tuna sirip kuning dengan formulasi tepung terigu : tepung tapioka : tepung ikan yaitu 100 g : 100 g : 75 g yang digunakan pada pembuatan produk stik. Pengujian produk stik ikan tuna sirip kuning meliputi uji hedonik dan uji kandungan gizi. Berdasarkan hasil uji hedonik yang mencakup parameter kenampakan, bau, rasa dan tekstur pada stik ikan tuna sirip kuning memperoleh nilai yang memenuhi standar SNI, yakni 7 (tujuh) untuk setiap kriteria. Pengujian kandungan gizi menunjukkan bahwa stik ikan tuna sirip kuning memiliki kadar air sebesar 5,11%, protein sebesar 24,11%, lemak sebesar 26,28%, serat sebesar 0,65%, abu sebesar 3,91%, dan karbohidrat sebesar 39,91%, sesuai dengan spesifikasi produk.
Efektifitas MA-11 dalam Meningkatkan Kecernaan Daun Kelapa Sawit Sebagai Pakan Ternak Alternatif
Authors: Sukaryani Sri , Brahmana Dewa Bayu , Ainul Yakin Engkus 
Published: February 2025

Penelitian ini dilakukan untuk mengetahui kecernaan Protein Kasar (KcPK) dan kecernaan Serat Kasar (KcSK) daun kelapa sawit yang terfermentasi MA-11 dengan lama perlakuan waktu inkubasi yang berbeda yaitu 0 hari, 3 hari, 6 hari, dan 9 hari. Data hasil pengamatan diolah menggunakan analisis ragam (ANOVA) dari Rancangan Acak Lengkap (RAL) dan uji lanjutan Duncan's Multiple Range Test (DMRT). Penelitian disusun dengan pengulangan empat arah yaitu T0 : daun kelapa sawit terfermentasi MA-11 selama 0 hari, T1 : daun kelapa sawit terfermentasi MA-11 selama 3 hari, T2 : daun kelapa sawit terfermentasi MA-11 selama 6 hari, dan T3 : daun kelapa sawit terfermentasi MA-11 selama 9 hari. Hasil penelitian menunjukkan kecernaan protein kasar daun kelapa sawit terfermentasi MA-11 paling tinggi terdapat pada T3 58,11% dan terendah pada T0 yaitu 19,48%. Kecernaan serat kasar daun kelapa sawit terfermentasi MA-11 paling tinggi terdapat pada perkaluan T3 67,08%, dan terrendah pada T0 yaitu 57,54%. Daun kelapa sawit yang difermentasi menggunakan 6 ml MA-11 dan diinkubasi selama 0 hari, 3 hari, 6 hari, dan 9 hari secara nyata meningkatkan kadar protein kasar dan serat kasar pada hari terlama.
ANALISIS KECERNAAN DAN PEMANFAATAN NUTRIEN PAKAN YANG MENGANDUNG TEPUNG KEPALA UDANG PADA KERAPU BEBEK (CROMILEPTES ALTIVELIS)
Authors: Ridwan Ridwan , Puspasari Andi Idris 
Published: February 2025

This research was aimed at finding out the effect of the shrimp head meal (SHM) content found in the feed on the nutrient digestibility and utilization of humpback grouper. The research was conducted in floating net cages, and it was arranged in a completely randomized triplicate designs. The treatments in this research were the SHM contents (0 %, 10 %, 20 %, 30 %, and 40 %) found in isonitrogenous and isocaloric diets. The data of each observed variable were analysed by using a one-way analysis of variance (ANOVA) in order to identify the effects of treatments on the nutrient digestibility and utilization. The difference in the treatment effects were determined by Duncan’s multiple range test at significance level of 0.05.The result of the research revealed that the protein digestibility in control diet was not significantly different from that of the diet containing SHM 10%. The protein digestibility decreased in the diets containing SHM of 20% to 40%. Meanwhile, the highest lipid digestibility was resulted from the control diet, and it decreased when SHM contents of the diets increased. The protein utilization (the protein retention and the protein efficiency ratio) and the feed efficiency (the feed conversion ratio) in the fish fed with control diet were not significantly different from those in the fish fed with the diet containing SHM of 10%. The decrease of the protein utilization and feed efficiency started to appear when the diet content of SHM had reached the level of 20%. The highest lipid retention was resulted from the control diet. The decrease of lipid retention started to appear when the diet content of SHM had reached the level of 10%. Based on the results, 10% of SHM could be included to the diet without any reduction in the protein digestibility and utilization and feed efficiency of humpback grouper.
AKTIVITAS ROLL ON AROMATHERAPY ESSENTIAL OIL DAUN KEMANGI (Ocimum sanctum L. ) SEBAGAI ANTIINFLAMASI
Authors: Desnita Eka , Rasyadi Yahdian , Nanda Annisa Destika 
Published: February 2025

Kemangi (Ocimum sanctum L.) merupakan tanaman aromatik yang mengandung senyawa kimia yang di ketahui memiliki aktivitas antiinflamasi. Tujuan dari penelitian ini adalah mengetahui aktivitas antiinflamasi dari sediaan roll on aromatherapy essential oil daun kemangi. Pengujian antiinflamasi yang digunakan menggunakan metode stabilisasi sel darah merah (eritrosit) secara in vitro dengan rentang konsentrasi minyak atsiri daun kemangi 15%-20%. Konsentrasi daun kemangi mampu menstabilisasi membran sel darah merah. Pada konsentrasi 15% memperlihatkan kemampuan stabilisasi terkecil yaitu 43,93% .Sedangkan pada konsentrasi 20% memperlihatkan kemampuan stabilitas terbesar yaitu 64,60%, dan pada konsentrasi 25% mengalami penurunan stabilitas sebesar 61,18%, namun , tidak signifikan bedanya dengan formula lain. Adanya pengaruh pemberian roll on aromatherapy essential oil daun kemangi (Ocimum sanctum L.) terhadap aktivitas antiinflamasi dengan metode stabilisasi membran sel darah merah, pada rentang konsentrasi minyak atsri daun kemangi 15-25%
Forming the Professional Identity of Future Teachers through Service-Learning
Authors: Rudneva I. A. , Kozyreva O. A. 
Published: February 2025

In this article, the reference to the phenomenon of the professional identity of future teachers is caused, firstly, by the need to update meanings that are subject to permanent changes in the social reality surrounding a person, and secondly, by the importance of this personal education for high results of professional and pedagogical activities. The problem of forming the professional identity of future teachers through service-learning has become the subject of a special pedagogical study for the first time. The purpose of the article is to present the results of the study on the possibilities of service-learning as means of forming the professional identity of future teachers at the stage of professional training.The study focuses on the analysis of the results of testing service learning as innovative means of professional training of future teachers at a pedagogical university, aimed at forming their professional identity. The classical pedagogical experiment included diagnostic, formative and control stages (N=216). Diagnostics was carried out using the identity stage scale by J. Cote, the identity styles questionnaire by M. Berzonsky, the general self-efficacy scale by R. Schwarzer & M. Jerusalem. The statistical qualification of the results was performed using the Pearson χ2 goodness-of-fit criterion.The case of the Volgograd State Social-Pedagogical University demonstrated that service learning is used as an effective means of forming the professional identity of future teachers: a) the emotional component of professional identity (involvement, interest, focus on solving socially significant problems); b) the communication component of the professional identity (enrichment of the experience of interpersonal communication and interaction with different gender, age and social groups); c) the activity – based component of the professional identity (development of technological skills and creativity).The results of the study can be applied to the development of the problem of the professional identity of future teachers, the study of the possibilities of service-learning as a pedagogical method; they contribute to the theory and practice of continuous pedagogical education.
Desarrollo de competencias investigativas en docentes: un enfoque multifactorial
Authors: Puche-Villalobos Deinny José , Acosta-Faneite Savier Fernando 
Published: February 2025

El estudio analiza factores que influyen en el desarrollo de competencias investigativas en docentes de seminarios y metodología de investigación de América del Sur, empleando un enfoque cuantitativo y un diseño no experimental. Se utilizó una muestra de 150 docentes y se recopilaron datos a través de encuestas validadas (coeficiente de confiabilidad = .98). Los resultados revelan que los indicadores institucionales tienen baja prioridad en Bolivia (60 %), Ecuador (46 %), Paraguay (46 %) y Venezuela (40 %). Además, la percepción de la preparación académica de los tutores varía; es moderada en Bolivia (53 %) y favorable en Argentina, Brasil, Ecuador y Venezuela (46 %). El interés estudiantil se presenta de manera ocasional y las habilidades cognitivas tienen variabilidad; esto subraya la necesidad de fortalecer los indicadores institucionales y mejorar la formación docente.
The Role of Long Non-coding RNA (NKILA and LINC00993) as Tumour Biomarkers in Breast Cancer
Authors: Mohamed Randa H. , Alkilany Mohamed M. , El-feky Hoda K. , Abd-elmoneim Bassel T. , Abd-Elmageed Amal F 
Published: February 2025

Background: Long non-coding RNAs (NKILA and LINC00993) are downregulated in breast cancer (BC) and can have potential use as a novel tumor biomarker. The Aim of the work is to investigate the LncRNAs (NKILA and LINC00993) and cytokines (NF-κB and CXCL-1) as potential biomarkers in BC.
Methods: This Cross-sectional study included sixty-four pairs of surgically resected human breast cancer tissues and adjacent breast tissues. Expressions of LncRNAs (NKILA, LINC00993) and (NF-κB, CXCL1) cytokines were detected using real-time quantitative polymerase chain reaction (qPCR) analysis,
Results: There was a significant decrease in LncRNAs (NKILA, LINC00993) levels in tumor tissue compared to normal tissue (P<0.001). Also, there was a significant increase in NF-κB and CXCL1 levels in tumor tissue compared to normal tissue (P<0.001). ROC curve analysis indicated that the LncRNAs (NKILA, LINC00993) expression levels could be considered a promising marker for the diagnosis of breast cancer patients with a sensitivity (90.6%, 92.2% respectively). Also, cytokines (NF-κB and CXCL-1) expression levels could be considered a promising marker for the diagnosis of breast cancer patients with a sensitivity and specificity of 87.5%, and 89.1% respectively).
Conclusion: These findings suggest that LncRNAs (NKILA, LINC00993) and cytokines (NF-κB and CXCL-1) can be used as novel biomarkers for breast cancer.
Kualitas Spermatozoa Kambing Saanen Hasil Separasi Seks Menggunakan Bovine Serum Albumin Dengan Perbandingan Konsentrasi Berbeda
Authors: Setiawan Pandu 
Published: February 2025

Teknologi separasi seks spermatozoa adalah teknologi yang dapat membuat pemisahan spermatozoa yang mengandung kromosom X dan Y, sehingga memungkinkan pembiakan ternak secara selektif berdasarkan jenis kelamin yang diinginkan agar dapat memberikan keuntungan lebih bagi peternak. Penggunaan medium bovine serum albumin (BSA) dalam riset ini bertujuan untuk mengetahui kualitas spermatozoa yang dihasilkan dari separasi seks dengan melihat kualitas spermatozoa berdasarkan motilitas individu dan viabilitas spermatozoa. Perlakuan yang digunakan yaitu perbedaan gradien atau konsentrasi BSA dengan P1 5:10% dan P2 15:20%. Materi penelitian yang dipakai adalah semen segar yang didapat dari seekor Kambing Saanen jantan berumur dua tahun yang diberi pakan hijauan dan konsentrat. Penelitian separasi seks spermatozoa dilaksanakan secara eksperimental di laboratorium menggunakan metode kolom albumin dengan perlakuan konsentrasi BSA yang berbeda. Hasil penelitian dianalisis menggunakan uji t test berpasangan dengan ulangan sebanyak delapan kali. Hasil penelitian menunjukkan bahwa motilitas individu spermatozoa pada P1 konsentrasi 5% = 64,30 ± 5,43% dan 10% = 64,61 ± 9,69% sedangkan pada P2 konsentrasi 15% = 57,22 ± 5,29% dan 20% = 54,58 ± 2,55% dan viabilitas spermatozoa rata-rata pada konsentrasi P1 konsentrasi 5% = 71,66 ± 11,80% dan 10% = 84,03 ± 6,61% sedangkan pada P2 konsentrasi 15% = 79,47 ± 4,51% dan 20% = 78,20 ± 5,17%. Disimpulkan bahwa spermatozoa dengan konsentrasi BSA 5:10% memiliki kualitas berdasarkan viabilitas dan motilitas individu yang lebih baik daripada spermatozoa dengan konsentrasi BSA 15:20%.