bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Review of the Cretaceous Ichnology of Tethys‐Related Basins in India: New Record From the Bagh Group
Authors: Shitole Apurva D. , Patel Satish J. , Darngawn Jehova Lalmalsawm , Joseph Jaquilin K. 
Published: January 2025

ABSTRACTThe Narmada Basin in west‐central India forms the northern part of the Central Indian Tectonic Zone (CITZ). The Cretaceous Bagh Group rocks of the Western Lower Narmada Valley (WLNV) succession was studied for sedimentary facies analysis and ichnology. Textural and mineralogical characteristics along with primary and secondary sedimentary structures revealed 11 lithofacies, of which the calcareous sandstone, fine‐grained sandstone‐siltstone‐shale and sandy/silty allochemic limestone lithofacies are highly bioturbated. WLNV contains a well‐preserved, less diverse, and relatively abundant ichnofauna; a total of 24 ichnospecies belonging to 15 ichnogenera with pseudotrace fossils are identified and described. The trace fossils belong to the Skolithos, Cruziana and Glossifungites Ichnofacies. The Skolithos Ichnofacies suggest an upper shoreface environment with moderate‐to‐high energy conditions and shifting substrate; the Cruziana Ichnofacies suggest a lower shoreface environment with low‐to‐moderate sedimentation rates and energy conditions and the Glossifungites Ichnofacies suggest dewatering of sediments and a slow rate of sedimentation. Early ichnological studies in the different Tethys‐related Cretaceous basins of the Indian subcontinent (Eastern Lower Narmada Valley, Kachchh, Cauvery, Jaisalmer, Barmer and Saurashtra) primarily focused on identifying the trace fossils, describing the new species and interpreting them in relation to trace producers and depositional environment. However, many of the ichnogenera and ichnospecies established from these basins need special attention because they either have been described as invalid, revised or assigned an unclear taxonomic status. The Cretaceous trace fossils reported to date from these basins are compiled along with their paleoenvironmental interpretation. The study also discusses the present status of the ichnogenera and ichnospecies names of the trace fossils reported to date from these basins. These data can be further used to enhance our understanding of how paleoenvironmental conditions control the distribution of trace‐making communities across space and time.
Prevalence and Hematological Changes in Urogenital Schistosomiasis: Infection Persistence in the Phase of Mass Drug Administration in Sempoa (Kwahu East, Ghana): A Cross‐Sectional Study
Authors: Boakye Alahaman Nana , Hatsu Neuwell , Akwetey Samuel Addo , Karikari Akosua Bonsu , Atta Simon Kwaku , Addae Mark Michael 
Published: January 2025

ABSTRACTBackgroundSchistosomiasis is a chronic neglected tropical disease and Ghana's second most prevalent helminth infection. The annual mass drug administration of praziquantel to school children is aimed at reducing disease morbidity as a public health problem.AimThe study aimed to assess the prevalence and hematological profile of urinary schistosomiasis in Sempoa after over a decade of consecutive Mass Drug Administration (MDA) of praziquantel.MethodsA community‐based cross‐sectional study involving 126 participants was conducted. Schistosoma haematobium eggs were identified and quantified using the urine filtration‐microscopy technique. The hematological profile was analyzed using a fully automated 5‐part Sysmex XN‐350 (Sysmex Co, Germany) analyzer.ResultsThe study recorded a prevalence of 21.6% that was significantly related to water contact activities. Schistosomiasis was significantly associated with lower levels of Red Blood Cell (RBC) indices; MCV (p < 0.001), MCHC (p < 0.001), and MCH (p = 0.01) with higher platelet, lymphocytes, and basophil counts compared to the uninfected. Heavy infection was significantly associated with lower hemoglobin levels. The study further reported microhaematuria as a sensitive and specific proxy diagnostic tool for field surveillance in endemic communities.ConclusionUrinary schistosomiasis accompanied by an altered hematological profile persists in Sempoa under preventive praziquantel. Future control interventions must consider an integrated approach of marrying behavioral change, with preventive chemotherapy and vector control.
Managing Doxorubicin Cardiotoxicity: Insights Into Molecular Mechanisms and Protective Strategies
Authors: Al khafaji Adnan Taan , Barakat Ali Mohammed , shayyal Akram Joudah , Taan Ali Adnan , Aboqader Al‐Aouadi Raed Fanoukh 
Published: January 2025

ABSTRACTCancer ranks as the second leading cause of death in the United States and poses a significant health challenge globally. Numerous therapeutic options exist for treating cancer, with chemotherapy being one of the most prominent. Chemotherapy involves the use of antineoplastic drugs, either alone or in combination with other medications, to target and kill cancer cells. However, these drugs can also adversely affect healthy cells, leading to various side effects. Among the most commonly used chemotherapy agents are anthracyclines, which include doxorubicin, daunorubicin, and epirubicin. Doxorubicin is particularly notable for its effectiveness but is also associated with significant cardiotoxicity, a common concern for patients undergoing chemotherapy. Unfortunately, there is currently no definitive treatment to prevent or reverse this cardiotoxicity. The cardiac effects of doxorubicin can manifest in several ways, including changes in electrocardiograms, arrhythmias, myocarditis, pericarditis, myocardial infarction, cardiomyopathy, heart failure, and congestive heart failure. These complications may arise during treatment, shortly after it concludes, or even weeks later. Various mechanisms have been proposed to explain doxorubicin‐induced cardiotoxicity. Key factors include the inhibition of topoisomerase IIβ, mitochondrial damage, reactive oxygen species (ROS) production due to iron metabolism, increased oxidative stress, heightened inflammatory responses, and elevated rates of apoptosis and necrosis within cardiac tissue. This review article will provide a comprehensive overview of the current state of knowledge regarding doxorubicin‐induced cardiomyopathy. We will explore the underlying molecular mechanisms contributing to this condition and discuss emerging therapeutic strategies aimed at mitigating its impact on cancer survivors.
On MSRD Codes, h‐Designs and Disjoint Maximum Scattered Linear Sets
Authors: Santonastaso Paolo , Sheekey John 
Published: January 2025

ABSTRACTIn this paper, we construct new optimal subspace designs and, consequently, new optimal codes in the sum‐rank metric. We construct new 1‐designs by finding sets of disjoint maximum scattered linear sets, and use these constructions to also find new ‐designs for . As a means of achieving this, we establish a correspondence between the metric properties of sum‐rank metric codes and the geometric properties of subspace designs. Specifically, we determine the geometric counterpart of the coding‐theoretic notion of generalised weights for the sum‐rank metric in terms of subspace designs and determine a geometric characterisation of MSRD codes. This enables us to characterise subspace designs via their intersections with hyperplanes and via duality operations.
An ATPS‐based droplet microfluidic device for protein partitioning
Authors: Moreno‐Sibaja Federico , Hernández‐Cid David , Ceballos‐Medina Javier , Cerón‐Torres Daniel Abirán , Reyes‐Avendaño Jorge Antonio , Gallo‐Villanueva Roberto Carlos , Pérez‐Gonzalez Victor Hugo , Mata‐Gómez Marco Arnulfo 
Published: January 2025

AbstractBackgroundDroplet microfluidics uses immiscible phases to manipulate discrete volumes inside microchannels, and it is applied in synthesis of biomolecules, encapsulation, drug delivery and cell analysis. The use of aqueous two‐phase systems (ATPS) is a strategy for the fractionation of biomolecules. Here, we combined both techniques to fabricate a microfluidic device based on a polymer–salt ATPS, composed of polyethylene glycol (PEG) 8000 and phosphate salt buffer (PO4), capable of generating droplets and partitioning red fluorescent protein (RFP), used as a model of study. Partition behavior, droplet size and frequency were characterized, employing a polydimethylsiloxane microdevice for this purpose.ResultsThe microdevice exhibited either a two‐phase or droplet behavior in the absence and presence of RFP. In both scenarios, the model protein was partitioned towards the salt‐rich phase (PO4), as in traditional ATPS. In addition, by controlling fluid velocity, different regimes of droplet formation were observed, i.e. dripping and jetting. RFP was partitioned and encapsulated in both regimes. The microdevices exhibited a partition coefficient, , of 0.34 ± 0.016, which is comparable with that obtained in traditional systems ( = 0.39 ± 0.012). Droplet size diminished as , , increased. Droplet breakup time has the same effect when increasing velocity ratio, while frequency of droplet formation increased. COMSOL computational simulations were performed, exhibiting good agreement with experimental results.ConclusionThe microfluidic device proved to be a useful platform to generate droplets by using polymer PEG–salt ATPS under controlled conditions. Besides, it allowed partitioning and encapsulation of the model protein. This microfluidic platform presents a viable alternative for protein separation and encapsulation, which can further support high‐value‐biomolecule separation. © 2025 Society of Chemical Industry (SCI).
Real‐World Data on Lymphoma in Adolescents and Young Adults (AYA)—Report From the Lymphoma and Related Diseases Registry (LaRDR)
Authors: Wong Evangeline Y. , Wellard Cameron , Ng Jun Yen , Chung Eliza , McQuilten Zoe K. , Opat Stephen , Wood Erica M. , Talaulikar Dipti 
Published: January 2025

ABSTRACTIntroductionLymphoma is a common malignancy among adolescents and young adults (AYAs) which is generally defined as 15–39 years. Relative to other age groups, lymphoma in AYAs remains understudied with heterogeneous treatment options.MethodsWe performed a retrospective review of patients aged 18–60 years in the Australasian Lymphoma and Related Diseases Registry (LaRDR) with new diagnoses of the common subtypes of lymphoma in AYAs between January 2016 and April 2023. The subtypes are classic Hodgkin lymphoma (cHL), diffuse large B‐cell lymphoma (DLBCL), primary mediastinal B‐cell lymphoma (PMBCL) and Burkitt lymphoma (BL). Patient demographics, disease characteristics, treatment and outcome data were collected, and comparisons were made between AYAs (18–39 years) and older adults (OAs) (aged 40–60).ResultsAYAs had higher rates of cHL and PMBCL whereas OAs presented more frequently with DLBCL. AYAs with cHL and PMBCL had higher rates of early‐stage and low‐risk disease than OAs. In contrast, both AYAs and OAs were more likely to present with advanced‐stage DLBCL and BL. AYAs with cHL were more likely to be treated with BEACOPP as compared to OAs who were more commonly treated with ABVD. There was no significant difference in treatment regimens for DLBCL, PMBCL or BL between AYAs and OAs. AYAs with cHL had better overall survival (OS) compared to OAs; specifically, cHL AYAs had better OS and DLBCL AYAs had better progression‐free survival (PFS) and OS compared to OAs.ConclusionThe study provides valuable data on patient and disease characteristics, treatments used and outcomes in AYA compared to OA aged 40–60 years. Registry data such as from LaRDR can help improve treatment standardisation and AYA patient outcomes.Trial RegistrationThe authors have confirmed clinical trial registration is not needed for this submission
The Effect of Cryopreservation on the Bone Healing Capacity of Endothelial Progenitor Cells in a Bone Defect Model
Authors: Hali Kalter , Gagnon Stéphane , Raleigh Matthew , Ali Ikran , Sniderman Jhase , Halai Mansur , Hall Jeremy , Schemitsch Emil H. , Nauth Aaron 
Published: January 2025

ABSTRACTEndothelial progenitor cells (EPCs) have proven to be a highly effective cell therapy for critical‐sized bone defects. Cryopreservation can enable long‐term storage of EPCs, allowing their immediate availability on demand. This study compares the therapeutic potential of EPCs before and after cryopreservation in a small animal critical‐sized bone defect model. Five‐millimeter segmental defects were created in the right femora of Fischer 344 rats, followed by stabilization with a miniplate and screws. The animals received 2 × 106 fresh EPCs (n = 7) or 2 × 106 cryopreserved EPCs (n = 9) delivered on a gelatin scaffold. Cryopreserved EPCs were stored for 7 days at −80°C prior to thawing and loading onto the gelatin scaffold. Biweekly radiographs were taken until the animals were euthanized 10 weeks after surgery. The operated femora were then evaluated using microscopic‐computed tomography (micro‐CT) and biomechanical testing. All animals treated with fresh (n = 7/7) or cryopreserved (n = 9/9) EPCs achieved radiographic union at 10 weeks. Animals treated with fresh EPCs had statistically significant higher radiographic scores at 2 weeks (p < 0.05) but showed no statistically significant differences thereafter (p > 0.05). Micro‐CT analysis showed no statistically significant differences between the groups in bone volume (BV) or BV normalized to total volume (p > 0.05), with excellent bone formation in both groups. Finally, there were no differences in biomechanical outcomes between the groups (p > 0.05). These results demonstrate that cryopreserved EPCs are highly effective and equivalent to fresh EPCs for healing critical‐sized bone defects in a rat model of nonunion.
Digital Transformation, Internationalisation and ESG Performance of Multinational Companies
Authors: Xu Xin , Sun Meiya 
Published: January 2025

ABSTRACTThis study examines the impact and mechanism of digital transformation on the corporate environmental, social and governance (ESG) performance of Chinese A‐share listed multinational companies (MNCs) from 2011 to 2021. Corporate digital transformation can enhance ESG performance by reducing institutional distance, improving internal control quality and absorptive capacity. The level of internationalisation also has a positive impact on this relationship. The positive effect of digital transformation on the ESG performance of MNCs is more pronounced in non–high‐tech industries and mature companies. This study offers theoretical support for improving MNCs' ESG performance and managing cross‐border operational risks through digital transformation.
Convergence and Coupled Best Proximity Points: Ulam–Hyers Stability and an Application to a Two‐Person Game
Authors: Mongkolkeha Chirasak , Gopal Dhananjay , Dechboon Premyuda , Khammahawong Konrawut 
Published: January 2025

ABSTRACTThis paper aims to establish the uniqueness of a coupled best proximity point for cyclic Kannan contraction mappings in the setting of uniformly convex Banach spaces. The stability of the coupled best proximity point problem under the Ulam–Hyers framework is also studied. Since the existence of a noncooperative equilibrium is equivalent to the existence of a coupled fixed point, our results can be effectively applied to solve the problem of finding a noncooperative equilibrium in two‐person games. Furthermore, we present illustrative examples to support our findings.
Induced Pseudomembrane Enrichment in Long Nerve Allograft Reconstruction
Authors: Protzuk Omar A. , Samuel Mariam A. , Seward Kriston R. , Keshishian Christopher A. , Bendale Geetanjali S. , Isaacs Jonathan E. 
Published: January 2025

ABSTRACTIntroduction/AimsLong nerve defects are typically reconstructed with autograft or processed acellular nerve allograft (PNA). PNA is convenient and avoids donor morbidity but lacks the neurotrophic environment of autograft. Increased levels of neurotrophic factors have been identified in pseudomembranes induced around silicone implanted between nerve ends. This study aimed to determine if pseudomembrane can be reliably induced around silicone implanted between nerve ends, and if this enhances regeneration of PNA inset within using a staged technique.MethodsLewis rats (n = 24) underwent resection of a 15‐mm sciatic nerve. The defect was filled with a silicone tube (n = 12) (MA) or the nerve ends were secured to a muscle bed (n = 12) (NMA). After 4 weeks, the silicone was replaced with PNA threaded within the pseudomembrane tunnel. In both groups, PNA was used to reconstruct the nerve defect. Weekly neuromotor assessment was performed with sciatic function index (SFI). At 16 weeks, muscle recovery was assessed, and nerve samples were obtained for histomorphometry.ResultsThe MA group's average normalized muscle weight was 46.25% versus the NMA group's 33.19% (p < 0.05). The MA group's average normalized muscle girth was 78.25% versus the NMA group's 60.73% (p < 0.05). Axon counts, g‐ratio, and muscle force were not statistically different. At Week 15, the MA group had a significantly higher average SFI: −82.25 versus the NMA group −95.03 (p < 0.05).DiscussionPNA inset within induced pseudomembrane sheath enhanced muscle reinnervation. A staged membrane enhancement technique may be effective for improving PNA efficacy in peripheral nerve injury reconstruction.
A Bernoulli‐Barycentric Rational Matrix Collocation Method With Preconditioning for a Class of Evolutionary PDEs
Authors: Luo Wei‐Hua , Gu Xian‐Ming , Carpentieri Bruno , Guo Jun 
Published: January 2025

ABSTRACTWe propose a Bernoulli‐barycentric rational matrix collocation method for two‐dimensional evolutionary partial differential equations (PDEs) with variable coefficients. This method absorbs Bernoulli polynomials and barycentric rational interpolations as the basis functions in time and space, respectively. The theoretical accuracy of the proposed numerical scheme is proven to be , where is the number of basis functions in time, and and are the grid sizes in the and directions, respectively. Additionally, . To efficiently solve the linear systems arising from the discretizations, we introduce a class of dimension‐expanded preconditioners that leverage the structural properties of the coefficient matrices. A theoretical analysis of the eigenvalue distributions of the preconditioned matrices is provided. The effectiveness of the proposed method and preconditioners is demonstrated through numerical experiments on real‐world examples, including the heat conduction equation, the advection‐diffusion equation, the wave equation, and telegraph equations.
Optimized Multi‐Scale Attention Convolutional Neural Network for Micro‐Grid Energy Management System Employing in Internet of Things
Authors: Vetriveeran Divya , Sambandam Rakoth Kandan , Sekar Thaiyalnayaki , Venkatachalam Arul 
Published: January 2025

ABSTRACTThe combination of micro‐grid energy management systems (EMSs) with the Internet of Things (IoT) offers a promising way to improve energy use and distribution. However, challenges such as device compatibility and the difficulty of managing energy efficiently make it hard to implement these systems effectively. This study offers a significant advancement in energy management by using IoT for microgrid systems. An Optimized Multi‐scale Attention Convolutional Neural Network for microgrid EMS employing IoT (OMACNN‐MGEMS‐IoT) is proposed in this study, which enables efficient monitoring and control of energy resources. The proposed model's input data are gathered from the MQTT dataset. This research employs a Regularized Bias‐aware Ensemble Kalman Filter (RBAEKF) for pre‐processing input data, ensuring the removal of outliers and updating missing values. The MACNN is then used for effective fault detection within the microgrid. To enhance its performance, the Sheep Flock Optimization Algorithm (SFOA) is introduced to optimize the MACNN parameters, ensuring accurate fault detection. Implemented on the MATLAB platform, the performance of the OMACNN‐MGEMS‐IoT method is assessed through various performance metrics, demonstrating significant improvements. Notably, the proposed method achieves higher cost reductions of 25%, 22%, and 26% compared to existing approaches such as the IoT platform for energy management in multi‐micro grid systems (IoT‐PEM‐MMS), a micro‐grid system infrastructure implementing IoT for efficient energy management in buildings (MSII‐IoT‐EEM) and a hybrid deep learning‐based online energy management scheme for industrial microgrids (HDL‐OEM‐IM). The findings highlight the impact of the proposed OMACNN‐MGEMS‐IoT method in enhancing energy efficiency and cost‐effectiveness in microgrid systems.
Silver‐Catalyzed Decarboxylative Coupling of Oxamic Acids with Styrenes to Synthesize E‐Cinnamamides: A Distinguish Reaction Pathway
Authors: A Ru‐Han , Huo Yong‐Wang , Wu Xiao‐Feng 
Published: January 2025

AbstractA silver‐catalyzed decarboxylative coupling of oxamic acids with styrenes has been developed to produce E‐cinnamamides. Oxamic acids act as efficient precursors for carbamoy radicals. Based on the mechanistic experiments and intermediate analysis, the proposed mechanism involves radical addition to styrenes, followed by oxidation and solvent participation, ultimately leading to the formation of cinnamamides which is different from the reported cases.
Investigating the Association Between Human Resource Management Practices and Job Autonomy on Faculty Job Performance: Evidence From UAE Higher Education Sector
Authors: Mahade Ahmed , Elmahi Abdallah , Abdalla Alaa Amin , Said Raed A. , Alomari Khaled Mohammad 
Published: January 2025

ABSTRACTThis research delves into the interplay between Human Resource Management Practices (HRMPs) and job autonomy concerning faculty job performance within private universities in the United Arab Emirates (UAE) while considering the moderating role of faculty experience. The research explores how job autonomy and supportive HRMPs enhance job performance. The primary objective is to address the research gap concerning the functional independence of HRMPs and their impact on faculty job performance within higher education, specifically focusing on institutions in the (UAE). The significance of this research lies in the pivotal role of Human Resource Management (HRM) in higher education, as HRM has evolved from simply executing decisions to shaping strategic directions, making it a crucial factor in the success of universities through HRMPs related to finding and developing teaching staff to drive educational excellence. The HRMPs under scrutiny encompass recruitment, service ending, training, performance appraisal, promotion, and compensation as a cluster. A survey collected data from 225 faculty members, and statistical analysis was conducted using SPSS and SmartPLS software. The results reached through tests show a significant and positive impact of HRMPs and job independence on faculty performance. In addition, faculty members' experience affects the relationship between HRMPs, job independence, and faculty job performance as a moderating variable. This study has tremendous implications for tertiary institutions seeking to enhance the job performance of faculty members. It provides fresh insights into higher education and the specific context of the private tertiary sector in the UAE.