bluuebunny/crossref_metadata_2025_split huggingface dataset:
How firms adjust their SDG adoption in response to COVID-19 outbreak: a regional perspective
Authors: Montera Raffaella , Nevi Giulia , Cucari Nicola , Esposito De Falco Salvatore 
Published: October 2023

Purpose
This paper aims to examine the COVID-19 pandemic’s impacts on the regional progression toward the Sustainable Development Goals (SDGs) through the lens of the adoption of 2030 Agenda by firms from different Italian regions.

Design/methodology/approach
Mixed methods were adopted. First, a content analysis was performed on 330 nonfinancial declarations released in the 2019–2021 period by a sample of 110 Italian listed companies from different regional macroareas. Second, regression analyses were run to test the impact of regional localization of businesses on SDGs adoption over pre-/during/post-COVID era.

Findings
The regional localization of businesses does not affect the SDGs adoption in the pre-COVID-19 era because Italian firms mainly address social goals. Instead, SDGs adoption is affected by regional localization of businesses both during and post-COVID-19 age, when Northern firms prioritize economic and social goals, whereas Southern firms shift from social to environmental goals.

Originality/value
This study fills the need of considering the subnational specificities in literature on sustainable development by capturing connections between firms, belonging territory, SDGs and COVID-19 crisis.
The gender gap in voluntary turnover
Authors: Artz Benjamin 
Published: October 2023

PurposeThe study's objective is to measure the gender gap in quit behavior, consider whether it has changed over time and determine whether parenthood affects the gender gap in quit decisions.Design/methodology/approachThe quantitative study design leverages two separate USA data sources to analyze the gender gap in quits over time. Two separate cohorts confirm the study's results in Logit, ordinary least squares (OLS) and fixed effects estimations, using the Current Population Survey (CPS) and the National Longitudinal Survey of Youth (NLSY).FindingsAfter controlling for demographic and job characteristics, individual and geographic fixed effects and local unemployment rates, the study finds that the gender gap in voluntary turnover has declined over time and that parenthood's effect on quit behavior has converged between genders.Originality/valueWomen earn less than men. One common explanation is women's propensity to interrupt their careers, often voluntarily, more so than men. Yet, the determinants and trends of this gender gap in quit behavior has not been given much attention in the literature, including the role of parenthood.
Research note: Application of refraction full‐waveform inversion of ocean bottom node data using a squared‐slowness model parameterization
Authors: da Silva Sérgio Luiz , Costa Felipe , Karsou Ammir , Capuzzo Felipe , Moreira Roger , Lopez Jorge , Cetale Marco 
Published: October 2023

AbstractFull‐waveform inversion is a wave equation–based imaging technique for obtaining subsurface model parameters by matching modelled with field data. Full‐waveform inversion is often formulated as a local optimization problem in which the model parameterization influences the gradient preconditioner and the convergence rate associated with the full‐waveform inversion objective function. Model parameterization governs the radiation pattern of the so‐called secondary Born source. In this work, we assess model parameterization effects on the estimation of P‐wave velocities using a three‐dimensional acoustic time‐domain full‐waveform inversion procedure. These include the three commonly used parameterization: velocity, slowness and squared slowness. In this context, we consider a field data set from a deepwater Brazilian pre‐salt field using a recently introduced circular shot ocean bottom node acquisition which favours refracted waves. The results reveal that the squared slowness model parameterization provides a satisfactory trade‐off between the reconstruction of the deep pre‐salt target area and convergence rate, saving 50% of runtime compared to the velocity and slowness cases.
Reducing the gap between rhetoric and reality: Use of Digital Service Standards for public service innovation through digital transformation in Australia
Authors: Patterson Eric , Agarwal Renu 
Published: October 2023

AbstractNearly a decade ago, the Australian Federal Government introduced a Digital Service Standard (DSS) for new and redesigned government services. This was an opportunity to encourage digital services and disruptive innovations to help the government improve citizens outcomes, and indeed there was a significant uptake in the digital services assessments offered by the program with key government agencies across health, human services, taxation, and education on board. However, by the 2020s the number of publicly visible assessments had significantly reduced. The initial broad adoption and recent reduction in numbers present an opportunity to explore the effectiveness of this government innovation management program that was ahead of its time. This paper reviews the impact of the DSS in fostering public service innovation and presents lessons learnt from the program. To perform this analysis, this research evaluates to what extent the DSS applied common private sector innovation management approaches of Innovation Process Management and Innovation Portfolio Management in the public sector. It also looks at the impact of these programs in encouraging specific types of modern digital innovations. The analysis draws on DSS assessments from 2015 to 2021 and considers how the program demonstrated public sector innovation leadership. This paper proposes a framework to improve the DSS by tailoring its approach for new and existing services, adopting specific standards to encourage incremental and disruptive innovations, and promoting more transparent reporting and funding of innovation management programs. This evaluation found that the DSS exemplifies Innovation Process Management in its use of stages and gates, and Innovation Portfolio Management in its use of targeted assessment criteria across innovation portfolios of various government agencies. The analysis also identified design limitations in the DSS as a whole of government innovation management approach due to its limited uptake in multiple large agencies and lack of specific standards to encourage different types of innovation. The impact of this research is to increase the adoption of the DSS and increase the innovation outcomes delivered by this government program. We conclude by reflecting some of the unique considerations in applying private sector innovation management practices in the public sector.Points for practitioners
Innovation management techniques are emerging but remain immature in the public sector.
Australia has shown leadership in Government Innovation Process and Portfolio Management.
Government must remain committed to innovation management programs and sharing the outputs of these programs.
Government Innovation Management Programs should build in flexibility to encourage different types of innovation.
Hospitalizations for non‐SARS‐CoV‐2 respiratory infectious diseases among patients on hemodialysis: A comparison before and during the coronavirus disease 2019 pandemic
Authors: Banshodani Masataka , Kawanishi Hideki , Moriishi Misaki , Takahashi Naoko , Shintaku Sadanori , Tsuchiya Shinichiro 
Published: October 2023

AbstractIntroductionThe impact of coronavirus disease 2019 (COVID‐19) infection control on other infections in patients with dialysis has not received sufficient consideration.MethodsWe compared hospitalization and mortality rates among patients who underwent hemodialysis (HD) at three dialysis centers before (March 2018–February 2020) and during (March 2020–February 2022) the COVID‐19 pandemic.ResultsThis study included 1696 patients undergoing HD (mean age, 70 years; 1099 men). Compared to before the COVID‐19 pandemic, the emergency hospitalization rate (per 100 dialysis patient‐years) for non‐severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) respiratory infectious diseases (IDs) (7.0 vs. 4.1, p < 0.001) significantly decreased during the COVID‐19 pandemic, whereas the hospitalization rates for other IDs were comparable. The mortality rates for non‐SARS‐CoV‐2 respiratory IDs were comparable before and during the COVID‐19 pandemic.ConclusionsHospitalizations for non‐SARS‐CoV‐2 respiratory IDs among patients undergoing HD may have decreased owing to the implementation of infection control measures for COVID‐19.
The impact of ice slurry as a medium on oxidation status and flesh quality of shrimp (Litopenaeus vannamei) during refrigeration storage
Authors: Guan Weiliang , Liu Tianyu , Yan Weibing , Cai Luyun 
Published: October 2023

AbstractOxidation of lipid and protein is a major reason of flesh quality deterioration during storage. In this work, cold storage (CS) and flake ice (FI) storage, as traditional strategies for live shrimp (Litopenaeus vannamei) sedation and refrigerated storage, showed remarkable oxidation damage of lipid and protein in shrimp flesh during storage. In contrast, ice slurry (IS), with good heat exchange capacity and contactability, stunned shrimp in a sudden and thus relieved antemortem stress, which resulted in reducing the reactive oxygen species and reactive nitrogen species accumulation, and the oxidation damage risk in flesh. Additionally, IS, as a storage medium acted an oxygen barrier, further inhibited the oxidation of lipid and myofibrillar protein (MP), as revealed by the lower thiobarbituric acid reactive substances level, carbonyl (CO) derives content, total disulfide bond (S–S) content, and the higher total sulfhydryl (SH) content in shrimp flesh during storage, compared with CS and FI. The sodium dodecyl sulfate‐polyacrylamide gel electrophoresis electrophoretogram pattern of MP also suggested better preservation of myosin heavy chain, myosin light chain, actin, and tropomyosin in IS, whereas these proteins degraded in CS and FI. Consequently, IS prevented the formation of cross‐linking caused by oxidation in MP, leading to improved shrimp flesh quality during refrigerated storage, as demonstrated by the better maintained hardness, springiness, and water‐holding capacity compared to CS and FI.
Artificial intelligence differentiates abdominal Henoch‐Schönlein purpura from acute appendicitis in children
Authors: Nie Dan , Zhan Yishan , Xu Kun , Zou Haibo , Li Kehao , Chen Leifeng , Chen Qiang , Zheng Weiming , Peng Xiaojie , Yu Mengjie , Zhang Shouhua 
Published: October 2023

AbstractObjectiveThis study aims to construct an artificial intelligence (AI) model capable of effectively discriminating between abdominal Henoch‐Schönlein purpura (AHSP) and acute appendicitis (AA) in pediatric patients.MethodsA total of 6965 participants, comprising 2201 individuals with AHSP and 4764 patients with AA, were enrolled in the study. Additionally, 53 laboratory indicators were taken into consideration. Five distinct artificial intelligence (AI) models were developed employing machine learning algorithms, namely XGBoost, AdaBoost, Gaussian Naïve Bayes (GNB), MLPClassifier (MLP), and support vector machine (SVM). The performance of these prediction models was assessed through receiver operating characteristic (ROC) curve analysis, calibration curve assessment, and decision curve analysis (DCA).ResultsWe identified 32 discriminative indicators (p < .05) between AHSP and AA. Five indicators, namely the lymphocyte ratio (LYMPH ratio), eosinophil ratio (EO ratio), eosinophil count (EO count), neutrophil ratio (NEUT ratio), and C‐reactive protein (CRP), exhibited strong performance in distinguishing AHSP from AA (AUC ≥ 0.80). Among the various prediction models, the XGBoost model displayed superior performance evidenced by the highest AUC (XGBoost = 0.895, other models < 0.89), accuracy (XGBoost = 0.824, other models < 0.81), and Kappa value (XGBoost = 0.621, other models < 0.60) in the validation set. After optimization, the XGBoost model demonstrated remarkable diagnostic performance for AHSP and AA (AUC > 0.95). Both the calibration curve and decision curve analysis suggested the promising clinical utility and net benefits of the XGBoost model.ConclusionThe AI‐based machine learning model exhibits high prediction accuracy and can differentiate AHSP and AA from a data‐driven perspective.
Overuse of EEG and ECG in children with breath‐holding spells and its implication for the management of the spells
Authors: Hellström Schmidt Sanna , Smedenmark Julia , Jeremiasen Ida , Sigurdsson Björn , Eklund Erik A. , Pronk Cornelis Jan 
Published: October 2023

AbstractAimBreath‐holding spells (BHS) are common in children, but evidence‐based clinical guidelines are lacking. We investigated a large population‐based cohort of BHS patients, to propose a refined description of typical BHS and guidelines for its management.MethodsIn a cross‐sectional retrospective study, patients diagnosed with BHS in Southern Sweden 2004–2018 were recruited. Disease characteristics and diagnostic data were collected from patient medical records.ResultsIn total, 519 patients, mean age at diagnosis 19.8 ± 13.8 months with equal gender distribution, were included. In 48.3%, BHS had already been diagnosed after one spell. During spells, 78.0% of patients were unresponsive. For 71.5%, atonic, tonic, tonic–clonic or myoclonic seizures were reported, and 78.0% of patients had a spell lasting less than 1 min. Electroencephalography was conducted in 30.4% and Electrocardiography in 45.1%. Six children (3.8%) had a pathological electroencephalogram, four of which had concomitant epilepsy and only 0.9% of children had electrocardiogram findings suggesting pathology, none showing long QT syndrome.ConclusionChildren with BHS were frequently subjected to unnecessary diagnostic interventions. We characterise a typical presentation of BHS and propose a management‐algorithm, which is expected to reduce unnecessary usage of electroencephalography and electrocardiography.
Novel subsets of peripheral immune cells associated with promoting stroke recovery in mice
Authors: Gu Yichen , Zhang Xiaotao , Li Huaming , Wang Rui , Jin Chenghao , Wang Junjie , Jin Ziyang , Lu Jianan , Ling Chenhan , Shao Fangjie , Zhang Jianmin , Shi Ligen 
Published: October 2023

AbstractAimsPeripheral immune cells infiltrating into the brain trigger neuroinflammation after an ischemic stroke. Partial immune cells reprogram their function for neural repair. Which immune cells promote ischemic brain recovery needs further identification.MethodsWe performed single‐cell transcriptomic profiling of CD45high immune cells isolated from the ischemic hemisphere at subacute (5 days) and chronic (14 days) stages after ischemic stroke.ResultsA subset of phagocytic macrophages was associated with neuron projection regeneration and tissue remodeling. We also identified a unique type of T cells with highly expressed macrophage markers, including C1q, Apoe, Hexb, and Fcer1g, which showed high abilities in tissue remodeling, myelination regulation, wound healing, and anti‐neuroinflammation. Moreover, natural killer cells decreased cytotoxicity and increased energy and metabolic function in the chronic stage after ischemic stroke. Two subgroups of neutrophils upregulated CCL signals to recruit peripheral immune cells and released CXCL2 to keep self‐recruiting at the chronic stage.ConclusionsWe identified subsets of peripheral immune cells that may provide potential therapeutic targets for promoting poststroke recovery.
Committing to behavior change: How to prevent dogs from visiting Atlantic Forest remnants?
Authors: Tostes Ribeiro Isabel , Pardini Renata , Morsello Carla 
Published: October 2023

AbstractBehavioral interventions have been applied to induce multiple pro‐environmental changes, yet testing their effects on biodiversity conservation is novel. For certain behaviors, a promising tool is changing the context within which people make decisions through nudges. One such behavior is dog restraining to prevent visits to natural areas, a worldwide source of negative impacts on wildlife. In this preliminary study, we experimentally tested the effects of two interventions (i.e., an informative video on conservation and an informative video plus commitment nudge) on changing dog management among rural owners. We then assessed interventions' effects on owners' behavior change (n = 52) and intention to keep the restraining practice in the future (n = 50). Both interventions promoted a momentary change in owners' behavior, but their effect sizes did not differ. Yet, neither treatment increased the owners' intention to maintain the restraining practices. Although nudges alone may not be the most appropriate solution to reduce the severe dog impacts on wildlife, they might be of practical relevance to conservation stakeholders who deal with threats that are not prone to mitigation through more traditional strategies (e.g., command and control).
Global harmonization of immediate‐release solid oral drug product bioequivalence recommendations and the impact on generic drug development
Authors: Kotsybar Joseph , Hakeem Susan , Zhang Lei , Jiang Wenlei 
Published: October 2023

AbstractImmediate‐release (IR) solid oral drug products constitute a significant portion of approved drug products and products under development. Bioequivalence (BE) assessment for these oral products is important for establishing therapeutic equivalence for generic products to their respective comparator products. In December 2022, the International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use (ICH) published the first new draft guideline on BE for IR solid oral dosage forms (M13A). To support the development of ICH M13A, we comprehensively reviewed the landscape of oral IR products approved by the U.S. Food and Drug Administration (FDA) and compared BE recommendations for these products in the current U.S. FDA and European Medicines Agency (EMA) BE guidances. We utilized databases including Drugs@FDA, Orange Book, and product‐specific guidances (PSGs) published on the U.S. FDA and EMA websites to collect information. Oral IR products account for 46% of all FDA‐approved new drug applications currently listed in Orange Book with 82.5% solids, 0.9% semi‐solids, and 16.6% liquids. For all published U.S. FDA PSGs for solid oral IR products, in vivo BE studies with pharmacokinetic (PK) endpoints account for 88% of BE approaches recommended. Of these PK BE studies, 86.5% recommended fasting and fed BE studies, while only 15.9% EMA PSGs recommended both fasting and fed BE studies. This review helps clarify the scope of U.S. solid oral IR products impacted by the new ICH M13A draft guideline and demonstrates how recommendations in draft ICH M13A could significantly harmonize BE recommendations for IR oral products to facilitate global drug development.
After Objectification: Locating Harm
Authors: Vince Rosa 
Published: October 2023

ABSTRACTIn this article I offer an analysis of harms associated with sexual objectification. Objectification can be benign, but harm tends to occur in three circumstances: (i) when objectification is non‐consensual, (ii) when a phenomenon that I term ‘context‐creeping’ occurs, and (iii) when the objectification is also enacting or reinforcing some kind of oppression. I defend the view that objectification is not always harmful, and I explain the popular intuition to the contrary by demonstrating that these three harm‐generating circumstances are especially prevalent. The phenomenon of ‘context‐creeping’ objectification is introduced to capture what is intuitively wrong with much objectification in media and advertising. This phenomenon describes when instances of sexual objectification (which may be, in themselves, benign) regularly occur outside sexual contexts, in a way that reinforces particular rape myths and thereby contributes to harms. This means that the ubiquity of discussion of pornography in the objectification literature is misleading, and a shift in focus to other media is warranted. I end with a warning, though: we should be very careful in how we respond to these problems, as attempts to mitigate any harms associated with objectifying media can badly misfire.
Structural brain feature is associated with changes of masticatory performance in healthy elderly people: Evidence from longitudinal neuroimaging research over two years
Authors: Chan Yu‐Ting , Lin Chia‐Shu 
Published: October 2023

AbstractBackgroundHuman neuroimaging studies have revealed the association between brain structure and masticatory function. However, the majority of the studies adopted a cross‐sectional design, which hardly reveals the change in masticatory function and brain structure between different timepoints, and the dynamical association between changes in masticatory function and changes in brain structure has not been elucidated.ObjectiveWith a longitudinal design, we assessed the association between changes in masticatory performance (MP) and regional brain volume.MethodsTwenty‐two elderly participants received assessments of the number of missing teeth and MP (via colour‐changeable chewing gum) when they entered the study (i.e. the initial stage, T0), approximately 6 months later (T0.5), and approximately 1–2 years later (T1). Difficulty of food intake was assessed using a questionnaire. The participants received magnetic resonance imaging (MRI) at T0 and T1. The brain volume of the motor‐related area was estimated using FreeSurfer for MRI data. The associations between different stages were analysed using Spearman's rho correlation coefficients.Results(1) Individually, a smaller volume of right primary motor cortex at T0 was associated with increased MP from T0 to T1, suggesting the brain's role in changing oral functions; (2) higher MP at T0 was associated with an increased volume of the left superior frontal cortex from T0 to T1p, suggesting a potential effect on brain plasticity, and (3) increased difficulty to eat was associated with decrease MP but not brain volume of motor‐related area.ConclusionsThe preliminary findings revealed a complicated pattern of structural brain features and masticatory function in elderly people, and either the hypothesis that the brain predisposes masticatory function or the hypothesis that mastication reshapes the brain is oversimplified.
High School Student and Caregiver Preferred Communication Method Regarding School Meals: A Qualitative Approach
Authors: Mansfield Dana , Sagan Dylan , O'Donnell Alexander J. , Takgbajouah Mary , Loiacono Bernardo , Clark Withington Margaret H. , Cory Molly , Buscemi Joanna 
Published: October 2023

ABSTRACTBACKGROUNDThis study examined student and caregiver preference for school communication and explored the feasibility and acceptability of a digital tool to assist with communication about school meal program between schools and families.METHODSThe study used qualitative methodology through youth focus groups and caregiver semi‐structured phone interviews. The study was conducted in 4 high schools in a large, urban city. The phenomenon of interest included the exploration of preferences regarding communication around school meal programs and feasibility and acceptability of a digital tool for communication and promoting the ordering of healthful foods in the school environment. Interviews were transcribed, coded, and analyzed through NVivo qualitative software using thematic analysis approach to examine themes.RESULTSForty‐seven students (ages 14‐21, grades 9‐12) participated in 7 focus groups and 24 caregivers participated in semi‐structured phone interviews. Three themes emerged around (1) communication preferences, (2) accessibility, and (3) extrinsic motivational factors for engagement in healthy eating behaviors.CONCLUSIONResults indicated that communication methods could potentially influence motivation and engagement in youth school meal participation.