bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prof. Dr. GÖKHAN HOTAMIŞLIGİL: Nobel’e doğru yürüyüşüne tanık olduğum Bir Bilim Adamı
Authors: AKAR Nejat 
Published: December 2023

Prof. Dr. Gökhan Hotamışlıgil, obezite, diyabet, karaciğer yağlanması ve kalp-damar hastalıkları gibi halk sağlığı için sorun oluşturan ve sık görülen kronik metabolik hastalıkların temel mekanizmalarını aydınlatmaya yönelik bilimsel buluşlara imza atmış bir bilim adamıdır.
Onun alanında çalışmayan ama gerçekleştirdiği buluşlarla Nobel Ödülüne yürüyüşüne şahit olan bir öğretim üyesiyim. Onu ilk kez tanıdığım 1987 yılından itibaren kesişen yollarımızın bir özetiyle, taşıdığı bir bilim adamında olması gereken özelliklerini, benim gözümden bu yazıda okuyacaksınız.
Prof. Dr. Türkan Saylan, Yönderim
Authors: YÜKSEL Ayse 
Published: December 2023

Özet
13 Aralık 1935 yılında, İstanbul’un Kandilli semtinde Leyla-Fasih Saylan çiftinin ilk çocuğu olarak dünyaya gelmişti. Sonra da üç oğlan bir kız kardeşi daha oldu, beş kardeş bahçeli bir evde gönüllerince çocukluk yaşadılar. İlk, orta eğitimini Kandilli’de aldı, sonraki yıllarda Kandilli Kız Lisesi Vakfı Başkanlığı da yaptığı Kandilli Kız Lisesinde, gündüzlü eğitim görürken, arkadaşları ve öğretmenleri ile güzel anılar biriktirdi. Türkan Saylan, okul arkadaşlarına çok önem verirdi, onlarla iletişimi yaşama veda edene kadar sürdü.
Üniversite eğitimine, İstanbul Tıp Fakültesi’nde başladı. Öğrenci iken evlendi, anne oldu, sağlık sorunları yaşadı ama hekim olmaktan vazgeçmedi. Mezuniyet sonrasında, Nişantaşı Sosyal Sigortalar Kurumu Cildiye Servisinde asistanlığa başladı. Asistanlık, sadece cilt hastalıklarını öğrenmek demek değildi, aynı zamanda, hastaların sosyal sorunlarını öğrenmek, çözümler üretmek, kliniği yönetmek idi.
Deri ve zührevi hastalıklar uzmanı oldu. Bursa’ya tayin olmuştu ama, İstanbul Tıp Fakültesi Dermatoloji Anabilim Dalı Başkanı Prof. Dr. Osman Yemni’den ‘Başasistanlık’ teklifi aldı ve 1968 yılında bu göreve başladı. 1971’de İngiliz Kültür Heyeti’nin bursuyla İngiltere'de ileri eğitim gördü. 1972 yılında doçent unvanını aldı.1974'te Fransa’da ve 1976’da İngiltere’de kısa süreli çalışmalar yaptı. Cüzzam hastalığı konusunda kendini geliştirdi. 1976 yılında, Cüzzamla Savaş Derneği’ni kurdu, cüzzam hastalarının tedavi ve sosyal sorunlarına çözümler bulmaya başladı.
Başasistan olarak girdiği dermatoloji kliniğinin kapısından, 2002 yılında emekli olarak çıktı. Yıllar içinde, birçok hasta tedavi etti, sosyal sorunları ile ilgilendi, tıp öğrencilerine ders verdi, onları tanımaya anlamaya çalıştı, çok sayıda asistan yetiştirdi, zaman zaman kliniğin yöneticiliğini yaptı, birçok proje üretti, çalıştı ama hep çalıştı. Çalışmak ona şifa idi, zamanı iyi yönetiyor, kısa zaman içinde çok iş üretiyor, kendine iyi gelecek sosyal ve sanat etkinliklerini de hiç kaçırmıyordu.
Kurucularından biri ve Genel Başkanı olduğu Çağdaş Yaşamı Destekleme Derneği(ÇYDD)’nde, 19 yıl boyunca başta kız çocuklarının eğitimi olmak üzere, okumak isteyen ama ekonomik koşulları yetersiz olan binlerce çocuğa eğitim yolunu açtı. Onların, okuyup meslek sahibi olmasını, kendi ayakları üzerinde durmasını sağladı.
THE EFFECT OF MAULI BANANA (Musa acuminata) STEMS AND BASIL LEAVES (Ocimum basilicum) EXTRACTS ON GIC DISCOLORATION
Authors: Norhayati Norhayati , Diana Sherli , Adhani Rosihan 
Published: December 2023

Background: The water settable GIC material is easily influenced by fluids and is hydrophilic which causes discoloration of the restoration. Chlorhexidine is the gold standard mouthwash and if used for a long period of time it can cause discoloration of the restoration because it contains chemicals, so an alternative mouthwash made from natural ingredients is needed. A mixture of mauli banana stem and basil leaves extract has a more optimal antibacterial ability. Objective: In general, this study aimed to analyze the effect of a mixture of Mauli banana stem (Musa acuminata) and basil leaves (Ocimum basilicum) extracts on discoloration of the water settable GIC. Methods: This research is a true experimental research with pre test and post test designs with control group design. This study was divided into three treatments, namely water settable GIC soaked in a mixture of extracts of banana stems and basil leaves at concentrations of 75%, 100%, and 0.2% chlorhexidine gluconate (positive control). Color measurement was carried out using a series of digital analysis tools consisting of a Samsung A1 macro camera, Peyond series PD-480 SL and the MATLAB application. Results: The results of the Kruskal-Wallis statistical test showed p value = 0.282 (> 0.05), meaning that there was no significant difference in color change between the three treatments. Conclusion: There is an effect of a mixture banana mauli stems (Musa acuminata) and basil leaves (Ocimum basilicum) extracts at concentrations of 75%, 100%, and 0.2% chlorhexidine gluconate on the discoloration of the water settable GIC. Keywords: Basil leaves (Ocimum basilicum), CIELAB system, discoloration, mauli banana stem (Musa acuminata), water settable GIC
EFFECTIVENESS OF HEALTH PROMOTION USING INSTAGRAM SOCIAL MEDIA TO INCREASE ORAL HEALTH LITERACY IN BANJARBARU SOUTH KALIMANTAN
Authors: Salsabila Dinda Andira , Adhani Rosihan , Hatta Isnur 
Published: December 2023

Background: Banjarbaru is the city with the lowest percentage in the South Kalimantan region regarding knowledge the ease of access to dental health services. This shows an illustration of the importance of health promotion so that people are more aware of the importance of maintaining dental and oral health. One strategy to achieve optimal health promotion is to use health promotion methods through social media. Instagram social media as a health promotion media has the advantage of being easy to access without being constrained by distance, time, and cost. Purpose: Analyzing the effectiveness of health promotion using Instagram social media to increase oral health literacy in adolescents at SMP Negeri 1 Banjarbaru. Methods: This studies uses a true experimental design method with a pretest-postest design with control design, the sampling technique is simple random sampling technique. The studies carried out at SMP Negeri 1 Banjarbaru with 92 respondents. Results: There is a difference in the oral health literacy pretest and posttest scores in interverence group, while in the control group there is no significant difference. The significance result of Mann Whitney test in the posttest session for the intervention and the control groups are 0.000 > 0.05 which means that there is a significant difference in oral health literacy scores between the posttest scores of the intervention group and the control group. Conclusion: Health promotion using Instagram social media is effective for improving oral health literacy. Keywords: Health promotion, oral health, oral health literacy, social media
GAMBARAN KEBIASAAN BURUK RONGGA MULUT DAN KEJADIAN MALOKLUSI PADA SISWA USIA 10-12 TAHUN
Authors: Aulia Yasmina , Wibowo Diana , Azizah Aulia , Setyawardhana R. Harry Dharmawan , Dewi Nurdiana 
Published: December 2023

Latar Belakang: Maloklusi merupakan masalah gigi dan mulut tertinggi urutan ke 3 setelah karies dan penyakit periodontal. Maloklusi di usia 10-12 tahun sering terjadi karena usia tersebut sudah memasuki fase kedua dari periode gigi bercampur. Beberapa kebiasaan buruk yang dapat menyebabkan maloklusi yaitu kebiasaan menghisap dan menggigit bibir, menggigit kuku, mengisap jari, bernafas melalui mulut, bruxism dan menjulurkan lidah. Indeks yang dapat digunakan pada periode gigi bercampur adalah Index Of Complexity, Outcome And Need (ICON). Tujuan: Untuk mengetahui gambaran kebiasaan buruk rongga mulut dan kejadian maloklusi pada siswa usia 10-12 tahun (Tinjauan pada siswa SDN Gambut 10 Kab. Banjar). Metode: Penelitian ini menggunakan metode desktiptif observasional dengan desain cross sectional. Teknik pengambilan sampel menggunakan simple random sampling pada anak usia 10-12 tahun sebanyak 46 anak. Data kebiasaan buruk diperoleh melalui wawancara orang tua siswa dan pemeriksaan klinis kepada siswa, sedangkan data kejadian maloklusi diperoleh dari pengukuran indeks ICON. Hasil: Hasil penelitian ini yaitu kebiasaan buruk menggigit kuku/benda asing paling banyak ditemui sebesar 10,9%. Responden usia 10 tahun mengalami kejadian maloklusi dengan tingkat keparahan maloklusi paling banyak sebesar 43,4%. Tingkat keparahan maloklusi yang terjadi pada anak dengan memiliki kebiasaan buruk masuk dalam kategori memerlukan perawatan paling banyak 17,4% dari pada tanpa memiliki kebiasaan buruk. Kesimpulan: Keparahan maloklusi berdasarkan indeks ICON banyak ditemukan pada anak usia 10 tahun dan tingkat keparahan maloklusi lebih banyak ditemui pada anak yang memiliki kebiasaan buruk rongga mulut. Kata kunci : ICON, Kebiasaan Buruk, Maloklusi
Caractériser l’enveloppe climatique future des jardins communs forestiers : une approche essentielle pour mieux raisonner l’adaptation des essences
Authors: Rihm Gaspard , Fady Bruno 
Published: December 2023

L’adaptation au changement climatique est un enjeu de gestion majeur pour les forêts françaises. Pour décrire et comprendre la variabilité génétique et la plasticité phénotypique des caractères d’intérêt pour l’adaptation, les jardins communs (dont les tests de provenances) sont un outil de choix. Nous décrivons dans ce travail un des réseaux forestier français majeur de tests en jardins communs (GEN4X), son amplitude écologique et, via une approche de modélisation de niche, sa sensibilité à un climat qui va en se réchauffant et s’asséchant au cours du siècle. Une attention particulière a été portée aux dispositifs situés en région méditerranéenne.
Messages clés :• Les jardins communs sont des outils pour tester l’adaptation des essences au climat futur• Les conditions climatiques actuelles et futures dans ces jardins ont été évaluées• La zone méditerranéenne préfigure les conditions du futur dans une grande partie de la France
Ilegítimos na transição entre o Império e a República: o caso do estado de São Paulo (1886-1900)
Authors: Scott Ana Silvia Volpi , Bassanezi Maria Silvia Casagrande Beozzo , Scott Dario 
Published: December 2023

No Brasil, o estudo da condição de legitimidade (filiação) é tópico que vem sendo tratado pela literatura especializada, tanto no âmbito da História quanto no da Demografia Histórica, sobretudo a partir da década de 1980. O objetivo deste artigo é contribuir para o avanço da temática, mapeando a incidência e a distribuição espacial da ilegitimidade no estado de São Paulo, no final do século XIX, a partir de uma perspectiva diferente daquela dos estudos já elaborados, especialmente em relação ao recorte temporal e às fontes utilizadas. Assim, foram analisados os dados sobre a filiação na população paulista a partir dos Recenseamentos Gerais da População Brasileira, realizados em 1890 e 1900, acrescidos de outras fontes de cunho estatístico, produzidas para o estado de São Paulo. Os resultados apontam um quadro diferenciado em relação às várias zonas que compõem o estado e, embora as fontes sejam distintas, corroboraram o papel fundamental da imigração internacional, pois, nas áreas onde ela foi mais intensa, verificou-se a queda nos percentuais da ilegitimidade.
The influence of objective and subjective knowledge on attitude and willingness to pay veterinary control number-certified livestock food product
Authors: Syahlani Suci Paramitasari , Wankar Tian Jihadhan , Triatmojo Agung 
Published: December 2023

<p><strong>Objective: </strong>This study aims to analyse the effect of objective and subjective knowledge on attitude and willingness to pay for veterinary control number certified-livestock food products.</p><p><strong>Methods: </strong>The study was conducted by survey design. Respondents were determined by a judgmental sampling method with the criteria that respondents were at least 19 years old and contribute as full or part decision makers of food buying for him/herself or their families. Data were collected online by using questionnaires and analyzed using structural equation modelling with partial least squares software.</p><p><strong>Results: </strong>The results showed that objective knowledge (β=0.20, t=1.97) positively affected attitude toward VCN-certified livestock food product, while subjective knowledge did not affect (β= -0.10; t=1.44). Then, attitude toward VCN-certified livestock food product (β=0.29; t=3.73) affected willingness to pay for VCN-certified livestock food product. Furthermore, willingness to pay was influenced directly by subjective knowledge (β=0.34; t=6.37) but objective knowledge was not influenced significantly (β=-0.07; t=1.26). The R<sup>2</sup> value for attitude toward VCN-certified livestock food product was 0.05 and willingness to pay was 0.18.</p><p><strong>Conclusions: </strong>This study concluded that willingness to pay for VCN-certified livestock food product is directly influenced by subjective knowledge, and indirectly by objective knowledge through attitude toward VCN-certified livestock food product. <strong></strong></p>
The Francovich Principle as the Basis of State Responsibility for Laborer Loss Due to Company Bankruptcy
Authors: Widyantoro Agus , Taufiqurrohman Moch. Marsa , Nugraha Xavier 
Published: December 2023

<div class="WordSection1"><p><em>The absence of legal certainty in the application of the pari passu pro rata parte principle in the distribution of bankrupt accounts in Indonesia has given rise to uncertainty regarding the protection of the rights of laborers whose employers or companies have faced bankruptcy. This article considers that Indonesia requires a set of formulations enabling the state to provide legal protection for the rights of laborers affected by employer or company bankruptcy. The article explores the feasibility of adopting the Francovich Principle in Indonesia, defining it as a principle holding the state accountable for the losses incurred by laborers due to company bankruptcies. The article concludes that several conditions must be met to apply the Francovich Principle, including the establishment of a guarantee institution, the obligation for financial contributions from companies, and the implementation of specific measures to prevent abuse. The state’s effort to adopt the Francovich Principle involves establishing a priority scale in drafting laws related to the Francovich Principle into the Priority National Legislation Program. Furthermore, the government needs to revitalize institutions related to the Francovich Principle within the national legal and regulatory system</em></p></div>
Impact of Renewable Energy Sources on the Electricity Generation Cost
Authors: Liubchyk V. A. 
Published: December 2023

The study involves scenario modeling based on the construction of energy chains that determine the flow of energy from the extraction and import of energy resources through technologies for transforming energy forms, transmission and distribution to the final consumer. A fundamental model of the energy system of the Republic of Belarus was also built. The principle of minimizing total system costs is chosen as the objective function for modeling, provided that a number of restrictions imposed on the power system are met. For the purpose of energy system balancing, it was proposed to use the potential of hydropower, viz. existing hydroelectric power plants for scenario 1 and technically possible potential for scenario 2. As a result of the modeling, the structure of electricity production was obtained according to two scenarios. Based on the resulting structure, the cost of producing electrical energy was determined. Two approaches were considered: approach 1 that took into account the cost of electricity production at nuclear power plants which can be classified as new, and approach 2 that took into account the cost of electricity production at nuclear power plants, which can be attributed to the existing generation. The production cost of electricity by 2030 is predicted. When approach 1 is used its level is of 63.3 US dollars/(MW·h) under scenario 2 versus 65.3 US dollars/(MW·h) under scenario 1; when approach 2 is used, its level is of 37.5 US dollars/(MW·h) versus 39.4 US dollars/(MW·h), respectively. Also, the economically feasible potential for using solar energy was determined, which by 2025 will amount to 0.91–1.45 billion kW·h/year, and by 2030 – 2.15–3.46 billion kWh/year; the same for wind energy is 1.55–2.39 billion kW·h/year and 3.69–5.67 billion kWh/year, respectively; the same for hydropower is 1.11–1.45 billion kW·h/year throughout the entire period under review until 2030. Based on the study, it became possible to find out that in the Republic of Belarus it is economically feasible and technically possible to replace up to 20.0 % of electrical energy generation by 2030 with energy produced from renewable energy sources.
Ensuring Uniform Material Removal with Magnetic Abrasive Finishing of Semiconductor Wafers by Mode Control of Machining Parameters
Authors: Stepanenko D. A. , Eromin E. S. 
Published: December 2023

The paper describes a solution technique for direct and inverse problems of modeling the process of magnetic abrasive finishing (MAF) of semiconductor wafers. Solution of the direct problem enables calculation of allowance removal function for the prescribed machining parameters, and solution of the inverse problem enables determination of machining parameters required for realization of the prescribed allowance removal function. The direct problem is solved by means of Preston equation, which is usually used for description of material removal rate when polishing optical parts. The inverse problem is considered in a matrix formulation, and its least squares solution is determined by means of generalized inverse Moore-Penrose matrix. Based on the solution of the direct problem with constant values of kinematic and magnetic machining parameters shows that MAF with constant values of machining parameters does not ensure uniformity of material removal. On the basis of numerical examples it is shown that close to uniform material removal can be ensured by control of magnetic machining parameters with the law of variation determined from solution of the inverse problem. It is demonstrated that the smoothness of solution of the initial ill-conditioned inverse problem can be improved by means of Tikhonov’s regularization, which in turn technically simplifies control of machining parameters
The Role of Colchicine in the Management of COVID-19: A Meta-analysis
Authors: Elshiwy Kholoud , Amin Ghada Essam El-Din , Nazmy Mohamed , Samir Rasha , Allam Mohamed Farouk 
Published: December 2023

Abstract

Background: The Coronavirus disease 2019 (COVID-19) pandemic has robustly affected the global healthcare and economic systems. The causative agent is coronavirus-2 (SARS-CoV-2). The clinical presentation of the disease ranges from a flu-like illness to severe pneumonia and death. Till September 2022, the cumulative number of cases exceeded 600 million worldwide and deaths were more than 6 million. Colchicine is an alkaloid drug that is used in many autoinflammatory conditions e.g., gout, familial Mediterranean fever, and Behçet’s syndrome.
Objective: The aim of the current study was to assess the evidence of colchicine effectiveness in COVID-19 treatment.
Patients and methods: A comprehensive review of the literature was done till May 2022 and yielded 814 articles after ranking the articles according to authors and year of publication. Only 8 clinical trials and cohort studies fulfilling the inclusion criteria were included for further steps of data collection, analysis, and reporting.
Results: The results showed that colchicine resulted in a significant reduction in the mortality rate among patients received colchicine in comparison with placebo or standard care (RR 0.35, 95%CI: 0.15- 0.79). Colchicine resulted in a significant decrease in the need for O2 therapy in patients with COVID-19 (RR 0.07, 95%CI 0.02-0.27, P=0.000024). However, colchicine had no significant effect on the following outcomes among COVID-19 patients: the need for hospitalization, ICU admission, artificial ventilation, and hospital discharge rate. Among the PCR confirmed COVID-19 patients, colchicine decreased the hospitalization rate (RR 0.75, 95%CI 0.57-0.99, P=0.042). However, colchicine had no effect on mortality and the need for mechanical ventilation among this subgroup.
Conclusion: Colchicine caused a significant clinical improvement among COVID-19 patients as compared with the standard care or placebo, in terms of the need for O2, and mortality. This beneficial effect could play a role in the management of COVID-19 especially severe cases.
Distribution pattern and optimum sample size of Wheat aphid Rhopalosiphum padi (L.) (Hemiptera: Aphididae) and their major predators
Authors: N Venkatesh Y , Padala Vinod K , Rajna S , Suroshe Sachin S. , Chander Subhash 
Published: December 2023

Abstract
Distribution indices such as variance to mean ratio (ID), Green's index (GI), Index of mean crowding (IMC), index of patchiness (IP), and Index of mean clumping (IDM) indicated the aggregated distribution of Rhopalosiphum padi, Coccinella. septempunctata and regular distribution of Cheilomenes sexmaculata in wheat crop. Taylor's power law regression for R.padi, C. septempunctata and C. sexmaculata showed a significant positive relationship between the mean population and variance. Aggregation parameter of Taylor's power law (b) were significantly > 1, as b = 2.039, 1.637, and 1.779, respectively in the first year, second year, and for pooled data. Iwao's mean crowding regression values were > 1 for R. padi, C.septempunctata, and C. sexmaculata with the coefficients of determination (R2) significantly high, indicating the aggregated distribution of the species. The optimum sample size (n) at 5%, 10%, and 20% precision levels for R. padi were 1265.20, 316.30, and 79.1 respectively with the mean population of R. padi as 5.0 aphids per tiller while the corresponding optimum sample size of 350 aphids/tiller, was observed to be 86.3, 21.6 and 5.4. In C. septempunctata sample size required is 324.8, 81.2, and 20.3 with a mean population of one beetle/m2 while the corresponding sample size with 18 beetles/m2 is 254.5, 63.63, and 15.9 at 5%, 10%, and 20% precision levels respectively.