bluuebunny/crossref_metadata_2025_split huggingface dataset:
Women Economic Rights in the Face of Climate Change in Uganda; A Case of Central and Western Uganda
Authors: Mukasa Comfort Hajra , Wamalwa Rose Nyarotso , Atieno Rosemary , Diefendorf Sarah , McCarty Elaine , Tigaiza Arnold , Businge Godliver 
Published: January 2025

Abstract

Background
Women's economic rights are pivotal for achieving gender equality and sustainable development. Despite global advancements, women in developing countries, particularly in Uganda, continue to face significant hurdles due to socio-cultural norms, legal barriers, and more recently climate change. In Uganda, efforts have been made to enhance gender equality, but their impact is limited, especially in rural districts. This study focused on selected districts to evaluate the status of women's economic rights, exploring the challenges and facilitators within the context of climate change.
Objective
To assess the status of women’s economic rights in Gomba, Butambala, and Kabarole districts, identifying the barriers and facilitators affecting these rights, and evaluating the impact of climate change on their economic empowerment.
Methods
This study employed a cross-sectional mixed-method approach in Gomba, Butambala, and Kabarole districts of Uganda, among 291 grassroots women aged 18 years and above engaged in agriculture and other ventures. A digitized semi-structured questionnaire was used for data collection. Descriptive statistics were performed to summarize the variables and inferential statistics, to explore relationships between independent variables and women’s economic rights using Stata version 15 software. Qualitative data were transcribed, coded, and analyzed thematically to provide insights into the contextual factors influencing women's economic rights.
Results
Of the 214 women in the study, 66.8% were aged 25–44, and 43% had attained secondary education. Nearly all (98.6%) engaged in income-generating activities, mainly farming (64%) and business/trade (26.5%). About 28.8% earned 300,000 Uganda shillings or more monthly, with 76.4% spending on school fees, 81.6% on health, and 50.5% on food. While 68.2% had access to land, only 33.6% legally owned it. Financial services were accessible to 86%, with 72.6% using loans and 40.2% having applied for one. Approximately 68% always participated in household income decisions. Close to half (47.7%) scored moderately on economic rights, and over 93% observed weather changes, such as decreased rainfall (69.9%) and increased droughts (63.8%), leading to reduced crop yields (76.8%) and crop damage (75.8%). Respondents adopted strategies like income diversification (42.6%), saving groups (31.6%), irrigation (30.6%), and crop diversification (29.2%).
Extracellular Vesicles: A Promising Therapeutic Approach to Alzheimer's Disease
Authors: Mehrabadi Shima 
Published: January 2025

Abstract:
Extracellular vesicles (EVs) are nano-sized membranous particles that are secreted by
various cell types and play a critical role in intercellular communication. Their unique properties
and remarkable ability to deliver bioactive cargo to target cells have made them promising tools in
the treatment of various diseases, including Alzheimer's disease (AD). AD is a devastating neurodegenerative
disease characterized by progressive cognitive decline and neuropathological hallmarks,
such as amyloid-beta plaques and neurofibrillary tangles. Despite extensive research, no
disease-modifying therapy for AD is currently available. However, EVs have emerged as a potential
therapeutic agent in AD due to their ability to cross the blood-brain barrier, deliver bioactive
cargo, and modulate neuroinflammation. This review provides a comprehensive overview of the
current knowledge on the role of EVs in AD and discusses their potential as a therapeutic approach.
It covers the mechanisms of action, potential therapeutic targets, and challenges and limitations
of EV-based therapies for AD.
Chemical Profiling, Antioxidant, and Antiproliferative Activities of
Algerian Cistus creticus L. Leaf Extracts: Evidence from In vitro and In
Silico Studies
Authors: Aouiffat Yacine , Benaceur Farouk , Bakchiche Boulanouar , kadi Imededdine , Berrabah Fathi , Gouzi Hicham , Bardaweel Sanaa K. , Shakya Ashok K. , Mohamed Asmaa S. , Ghareeb Mosad A. 
Published: January 2025

Background:
Research into oxidative stress, cancer, and natural products revealed
promising avenues for therapeutic intervention. Natural products are considered potent pharmaceuticals in combating oxidative stress and its relationship with cancer.

Methods:
This study was carried out to evaluate the chemical profile and antioxidant activities using
DPPH, ABTS, Phenanthroline, Cupric, Phosphomolybdenum, FRAP, Hydroxyl, Iron chelation in
vitro assays, and anticancer properties by MTT method of Cistus creticus extracts. The chemical
composition was determined using the LC/MS-MS technique. Therefore, in silico methods, particularly molecular docking and dynamic simulation were applied for molecular interaction analysis

Results:
The obtained results revealed a wide variety of phenolic compounds in all studied fractions, in their qualitative and quantitative distribution. In most antioxidant assays, the butanol and
ethyl acetate extracts exhibited the most effective effects, followed by the aqueous extract, while
the petroleum ether and chloroform fractions exhibited much lower activity in comparison with
standards. In parallel, ethyl acetate, n-butanol, and chloroform extracts exhibited potent antiproliferative activity against T47D and A549 cell lines, while the aqueous extract showed an IC50 in the
range of mg/ml. Moreover, the analysis of interactions identified compounds against particular
targets in studied cell lines using molecular docking showed a great affinity, especially for the
ligands Hesperidin, Luteolin-7-O-glucoside and Rutin. Also, the molecular dynamic simulation of
the interacting complexes Hesperidin-mTOR, Lutin-EGFR and Apigenin-HER2 revealed precise
interaction, providing insights into their stability and dynamic behavior. Furthe

Conclusion:
These findings confirmed the potential of Algerian Cistus creticus L. leaf extracts as
promising therapeutic molecules for combating oxidative stress and cancer.
Analysis of the Results of Experimental Studies of Sewage Sludge Treatment in the Biotechnology Laboratory
Authors: M.W. Parshikova , E.M. Mikryukova 
Published: January 2025

Background:
The use of bioreactors at sewage treatment plants solves an environmental
problem at water utilities in the Udmurt Republic, as sludge beds are overflowing
due to the fact that tens of tons of sewage sludge have been stored on sludge beds every
day since the 1980s and amount to hectares of land.

Objective:
The results of experimental studies on the processing of wastewater sludge in
the Biotechnology laboratory were analyzed to improve the efficiency of the technological
process for the disposal of organic waste using a biogas plant and a process activator.

Methods:
The methodology for preparing a biogas plant for entering the operating mode
and further operation is presented. An algorithm for experimental studies using a biogas
plant and obtaining biogas from organic waste is presented.

Results:
The article presents an analysis of the results of experimental studies of sewage
sludge treatment under periodic psychrophilic and, subsequently mesophilic operating conditions
of the bioreactor in relation to the climatic conditions of the Udmurt Republic. The results
of experimental studies in the article are presented in the form of graphical dependencies
of the volume of produced biogas on the temperature and duration of the process.

Results:
The article presents the dynamics of changes in the volume of produced biogas
depending on the increase in temperature and duration of the process under the mesophilic
operating mode of the bioreactor. On the first day of the experiment under the mesophilic
mode in the bioreactor, the volume of produced biogas was 2.15% (7.41 g) at a temperature
of 32 ° C; with increasing temperature, the volume of produced biogas increased. The
maximum biogas production was observed on the fifth day of the experiment under the
mesophilic mode and amounted to 7.66%, which corresponds to 26.41 g.

Conclusion:
The recommended loading volume of biomass into the bioreactor is 80 liters.
In accordance with the actual conditions of the sewage treatment facilities, the volume of
biogas produced will be 26,000 m3 of methane daily during the period of anaerobic fermentation
in the bioreactor. To solve the environmental problem, it is necessary to install a
complex of bioreactors at the water utilities of the Udmurt Republic.
A crise ambiental no capitalismo contemporâneo
Authors: Damasceno Wagner Miquéias 
Published: January 2025

Este artigo trata da crise ambiental global à luz da crítica marxista da exploração do trabalho. Trata, também, do conceito de sustentabilidade, fulcral no debate contemporâneo sobre meio ambiente. Apoiado nas observações do economista Roberto Moreira, argumento que a transposição desse conceito oriundo da Ecologia para as relações sociais traz consigo problemas de ordem epistemológica, sociológica e política à medida que desconsidera o papel desempenhado pelo trabalho na mediação entre o ser humano e a natureza e o antagonismo entre as classes sociais. Para fins de demonstração, tomo como ponto de partida a reflexão marxiana sobre a relação entre o ser humano e a natureza e as consequências ambientais deletérias da exploração do trabalho e da alienação.
O Brasil nas páginas da Coleção 'Cadernos do povo brasileiro'
Authors: Lovatto Angélica , Constâncio Douglas Rocha 
Published: January 2025

Este artigo resgata a história da Coleção Cadernos do povo brasileiro, publicada no Brasil de 1962 a 1964, que vendeu em torno de um milhão de exemplares. Seu objetivo foi circular textos com ideias e caminhos estratégicos e táticos para a revolução brasileira. A repressão desencadeada pelo golpe militar de 1964 encerrou a Coleção e destruiu as três instituições responsáveis por sua produção e divulgação: o ISEB, o CPC da UNE e a Editora Civilização Brasileira. A Coleção enfrentou fortes organizações anticomunistas como o IPES, o IBAD e a LIPL. O artigo discute a atualidade da Coleção, diante da contemporaneidade brasileira de enfrentamento às forças de extrema-direita, em crescente rearticulação desde, no mínimo, o início da década de 2010.
Implementation of a standard perioperative protocol reduces postoperative respiratory distress events in dogs undergoing surgical correction of brachycephalic obstructive airway syndrome
Authors: Hill Mason , Lepiz Mauricio Loria , Ida Keila Kazue , Rutter Christine , Mankin Kelley Thieman , Dickerson Vanna 
Published: January 2025

Abstract

OBJECTIVE
To determine whether a standardized perioperative protocol for patients undergoing brachycephalic obstructive airway syndrome (BOAS) surgery reduces the incidence of regurgitation, aspiration pneumonia, and respiratory distress in the postoperative period.

METHODS
The records of client-owned dogs referred to the Texas A&M University Small Animal Teaching Hospital for surgical correction of BOAS over 4 years (February 2019 to June 2023) were retrospectively reviewed. A perioperative protocol for patients undergoing surgical correction of BOAS was implemented in June 2021, which included preoperative cisapride and antacid administration, minimizing opioid use, and a slow recovery with nebulization of hypertonic saline. Patient factors, perioperative treatments administered, and complications identified in hospital were recorded and compared between pre- and postprotocol groups.

RESULTS
The pre- and postprotocol groups included 42 and 47 dogs, respectively. A significant reduction in postoperative respiratory distress events was identified after protocol implementation (postprotocol, n = 6 [12.77%]; preprotocol, 15 [35.71%]). Postoperative regurgitation (preprotocol, n = 15 [35.71%]; postprotocol, 23 [48.94%]) and aspiration pneumonia events (preprotocol, 4 [9.52%]; postprotocol, 3 [6.38%]) did not differ significantly between groups. More dogs enrolled after protocol implementation experienced historical regurgitation prior to BOAS surgery (postprotocol, n = 31 [65.96%]; preprotocol, 18 [42.86%]).

CONCLUSIONS
Standardized protocol implementation reduced postoperative respiratory distress events, but not postoperative regurgitation nor aspiration pneumonia events, in patients undergoing BOAS surgery at our institution. Prospective studies are required to further assess these findings.

CLINICAL RELEVANCE
Veterinarians performing surgery in BOAS patients should consider implementation of a protocol to proactively minimize complications in the postoperative period.
Influencia de startups en las Ciudades Creativas
Authors: Fernández-Torres María Jesús , Rando Cueto Lola , Del Pino Rodríguez-Veras Ainhoa 
Published: January 2025

El concepto de Ciudad Creativa surge del área de las ciencias económicas denominada “economía creativa”. En este marco son relevantes las actividades, bienes y servicios con capacidad de dinamizar la economía (Herrera-Medina et al., 2013). Como ejemplo, las startups cobran interés, como fuente de innovación, al implementar nuevas tecnologías para reinventar modelos de negocio (Aljalahma y Slof, 2022). Según Informa D&B (2022), el 62% de startups españolas se concentra en Madrid, Cataluña y Andalucía. El objetivo es analizar la influencia de las primeras sobre dichas comunidades autónomas y estudiar su tratamiento en prensa. Se realiza una revisión sistemática de literatura científica de más de un centenar de trabajos, así como un análisis de contenido de 255 piezas informativas publicadas en Google News en 2024. Se abordan claves que relacionan a las startups, como motor económico, en la promoción de Ciudades Creativas y en la construcción de la Marca Ciudad.
Perancangan Prototype Berbasis Mobile Menggunakan Design Thinking Pada Siakad UNU Kalbar
Authors: Winandy Fikri , Mutiah Nurul , Rusi Ibnur 
Published: January 2025

SIAKAD Universitas Nahdlatul Ulama Kalimantan Barat merupakan sistem yang digunakan UNU Kalbar untuk mengelola data akademik bagi mahasiswa maupun dosen. Saat ini SIAKAD UNU Kalbar memiliki permasalahan yang didapat melalui wawancara yaitu banyak mahasiswa yang berpendapat akan lebih memudahkan jika SIAKAD dapat digunakan di aplikasi mobile karena dapat mengakses SIAKAD tersebut dimana saja. Selain itu pihak Biro Administrasi Perencanaan dan Pengembangan Sistem Informasi serta Operator Sistem Informasi Akademik UNU Kalbar menginginkan sistem di UNU Kalbar maju, artinya pihak UNU Kalbar ingin SIAKAD mengikuti perkembangan teknologi tanpa harus menggunakan pihak ketiga. Namun sebelum membangun aplikasi mobile, dapat dilakukannya perancangan prototype tampilan antarmuka dahulu. Hal itu untuk meminimalisirkan kegagalan sistem yang akan dibangun serta agar perancangan yang dibuat sesuai dengan kebutuhan pengguna. Oleh karena itu, untuk memastikan SIAKAD mobile UNU Kalbar sesuai dengan kebutuhan diperlukannya perancangan tersebut. Penelitian ini bertujuan untuk membuat perancangan prototype tampilan antarmuka berbasis mobile menggunakan pendekatan Design Thinking pada SIAKAD UNU Kalbar dengan beberapa tahapan yaitu Emphatize, Define, Ideate, Prototype, dan Test yang dimana hasil dari Perancangan tersebut dapat menjadi rekomendasi untuk pembuatan aplikasi SIAKAD berbasis mobile. Pada tahapan Test menggunakan Maze Design dengan skor 76 dan Usability Testing metode System Usability Scale dengan skor 74,08 yang berarti menurut pengukuran milik John Brooke termasuk ke dalam skala kategori nilai C, skor adjektif bernilai Good, dan skala penerimaan termasuk Acceptable. Hasil dari penelitian menunjukkan bahwa perancangan prototype tampilan antarmuka berbasis mobile pada SIAKAD UNU Kalbar mendapatkan respon yang positif dari pengguna. Kata kunci : Sistem Informasi Akademik, Aplikasi Mobile, Design Thinking, Usability Testing
Sistem Pemantauan dan Pengeringan Sepatu Otomatis Berbasis Internet of Things (IoT)
Authors: Pratama Rakha Daffa , Suhardi Suhardi , Hidayati Rahmi 
Published: January 2025

Sepatu sangat diperlukan dalam berbagai aktivitas seperti pergi ke sekolah, kampus, dan kantor. Sepatu yang sering digunakan perlu dicuci dan harus segera dikeringkan. Sepatu yang dibiarkan basah tanpa dikeringkan akan menyebabkan bau yang tidak sedap dan menjadi tempat berkumpulnya bakteri. Proses pengeringan sepatu umumnya dijemur di bawah sinar matahari, namun cara tersebut membutuhkan waktu yang cukup lama. Ketika cuaca cerah, terjadi hujan yang membuat proses pengeringan sepatu dengan memanfaatkan panas dari sinar matahari menjadi tidak efektif. Untuk solusi permasalahan ini, maka dikembangkan sistem pemantauan dan pengeringan sepatu otomatis berbasis IoT. Sistem ini mendeteksi kelembaban pada sepatu yang basah, agar dapat mengeringkan sepatu. Sistem ini mengirimkan notifikasi secara realtime ke chat bot telegram yang sudah ada di dalam grup Telegram, agar bisa memantau kondisi pengeringan sepatu kapanpun dan dimanapun. Sistem ini dapat mengirimkan notifikasi ke beberapa perangkat yang bisa digunakan oleh seluruh anggota grup Telegram. Hasil pengujian menunjukkan bahwa rata-rata waktu pengeringan sepatu pantofel 1 jam 5 menit 48 detik, rata-rata waktu pengeringan sepatu sneakers 1 jam 21 menit 48 detik, dan rata-rata waktu pengeringan sepatu olahraga 1 jam 30 menit 36 detik. Kata kunci : Sepatu, IoT, Notifikasi, Telegram
Análisis del Modelo de Desgaste Lineal de Archard, una Vista Dinámica al Modelo Original
Authors: Ortiz Santiana Kevin Alexander , Vicente Andrade Michael Paul 
Published: January 2025

El modelo Archard es un modelo lineal que describe el desgaste de un sistema deslizante. Sin embargo, si se desea aplicar este modelo a un sistema oscilante, se deben considerar algunas modificaciones y el uso de ecuaciones diferenciales puede ser una estrategia útil. En un sistema oscilante, las superficies de contacto realizan movimientos repetitivos hacia adelante y hacia atrás. Esto puede cambiar la forma en que se produce el desgaste porque las superficies pueden desgastarse en diferentes áreas. Además, la carga aplicada puede cambiar durante el ciclo de oscilación de una pieza, lo que también puede afectar al desgaste.
Para modelar este tipo de sistema, podría considerar el uso de ecuaciones diferenciales ordinarias o parciales, según la complejidad del sistema. Estas ecuaciones le permitirán modelar cómo cambia el desgaste de elementos metálicos con el tiempo y cómo depende de factores como la posición y la velocidad en el ciclo de vibración.
Sistema Web para la Dinamización de la Gestión de DNI en Entidades Gubernamentales Basado en SCRUM
Authors: Castañeda Rodríguez Christian Stephano , Galvez Mori Edisson Alejandro , Gerónimo Dionicio Percy Olivarez , Santos Fernández Juan Pedro , Sánchez Ticona Robert Jerry 
Published: January 2025

El presente documento describe el desarrollo de un sistema web para la gestión eficiente de Documentos Nacionales de Identidad (DNI) en entidades gubernamentales. Nuestro sistema se centra en proporcionar un control eficaz sobre las solicitudes de DNI, abarcando las tres modalidades existentes: emisión por primera vez, duplicado y renovación. Estas se pueden hacer tanto de manera presencial como de manera virtual, Además, el sistema permite agendar citas para cualquier tipo de trámite y brindar al ciudadano el estado en el que se encuentra dicho trámite a través de la plataforma virtual.
El desarrollo del sistema se realizó en tres etapas: Evaluación de Procesos, Diseño y Planificación del Proyecto, y Desarrollo y Validación del Proyecto. Esto se logró trabajando en base a la metodología SCRUM que permite mejorar la planificación y el diseño del proyecto, gracias a su adaptabilidad y flexibilidad.
Además, se incluyó los resultados de los indicadores económicos para este proyecto con el fin de conocer la viabilidad económica y verificar que si es beneficioso su implementación.
También se realizaron las pruebas de rendimiento utilizando diversas herramientas tecnológicas como Apache, JMeter para pruebas de cargas y de estrés obteniendo como resultados que el sistema acepta en promedio de 750 usuarios concurrentes. Estas pruebas aseguraron un sistema robusto, eficiente que proporciona una experiencia de usuario confiable y satisfactoria.
El sistema propone una solución íntegra para enriquecer la experiencia de los usuarios, incluyendo tanto a los empleados como a los ciudadanos. Este sistema acelera el proceso de manejo de documentos de identidad y ayuda a reducir significativamente el tiempo de espera para los ciudadanos al hacer sus trámites de manera virtual, lo que representa una oportunidad para actualizar los procedimientos en las instituciones gubernamentales.
Reabsorción radicular externa, reporte de tres casos clínicos
Authors: Piedra Andrade Melissa Nicole , Villa Sigchi Elian Mateo , Carvajal Endara Andrea Soledad 
Published: January 2025

Antecedentes: la reabsorción radicular externa es un proceso fisiológico o patológico que produce la pérdida de la estructura dental en la región externa de la raíz; cuando es patológico responde a una actividad no deseada e incontrolada de células clásticas, poniendo en riesgo a la pieza dental; su etiología es multifactorial, comúnmente provocada por traumatismos, hábitos parafuncionales, infección o ciertos tratamientos de ortodoncia. Objetivo: reportar 3 casos de pacientes diagnosticados con reabsorción radicular externa, con distinta terapéutica según su ubicación y severidad. Casos clínicos: el primer caso se trata de una reabsorción radicular externa apical en dientes anteriores, manejada con terapia periodontal higiénica y de mantenimiento; el segundo caso se trata de un diente con reabsorción radicular externa apical con pérdida avanzada de arquitectura de los tercios medio y apical, cuyo tratamiento fue exodoncia; y el tercer caso se trata de una reabsorción radicular externa apical generalizada y además cervical en el diente 3.3, con terapéutica quirúrgica, endodóntica y restauradora de esta pieza dental y tratamiento periodontal higiénico y de mantenimiento en toda la dentición. Conclusión: es de suma importancia realizar un diagnóstico imagenológico completo para determinar el tipo y extensión tridimensional de la reabsorción radicular externa; del mismo modo realizar los seguimientos imagenológicos pertinentes durante los tratamientos de ortodoncia, pues una vez identificada esta patología se requiere una valoración integral para definir el tratamiento pertinente a cada caso, que puede ir desde estrategias conservadoras hasta la exodoncia.