bluuebunny/crossref_metadata_2025_split huggingface dataset:
Flexible Bioinspired Healable Antibacterial Electronics for Intelligent Human‐Machine Interaction Sensing
Authors: Liu Kuo , Wang Mingcheng , Huang Chenlin , Yuan Yue , Ning Yao , Zhang Liqun , Wan Pengbo 
Published: December 2023

AbstractFlexible electronic sensors are receiving numerous research interests for their potential in electronic skins (e‐skins), wearable human‐machine interfacing, and smart diagnostic healthcare sensing. However, the preparation of multifunctional flexible electronics with high sensitivity, broad sensing range, fast response, efficient healability, and reliable antibacterial capability is still a substantial challenge. Herein, bioinspired by the highly sensitive human skin microstructure (protective epidermis/spinous sensing structure/nerve conduction network), a skin bionic multifunctional electronics is prepared by face‐to‐face assembly of a newly prepared healable, recyclable, and antibacterial polyurethane elastomer matrix with conductive MXene nanosheets‐coated microdome array after ingenious templating method as protective epidermis layer/sensing layer, and an interdigitated electrode as signal transmission layer. The polyurethane elastomer matrix functionalized with triple dynamic bonds (reversible hydrogen bonds, oxime carbamate bonds, and copper (II) ion coordination bonds) is newly prepared, demonstrating excellent healability with highly healing efficiency, robust recyclability, and reliable antibacterial capability, as well as good biocompatibility. Benefiting from the superior mechanical performance of the polyurethane elastomer matrix and the unique skin bionic microstructure of the sensor, the as‐assembled flexible electronics exhibit admirable sensing performances featuring ultrahigh sensitivity (up to 1573.05 kPa−1), broad sensing range (up to 325 kPa), good reproducibility, the fast response time (≈4 ms), and low detection limit (≈0.98 Pa) in diagnostic human healthcare monitoring, excellent healability, and reliable antibacterial performance.
Ordered Mesoporous High‐Entropy Intermetallics for Efficient Oxygen Reduction Electrocatalysis
Authors: Wang Yanzhi , Zhang Xin‐Yu , He Hangjuan , Chen Jie‐Jie , Liu Ben 
Published: December 2023

AbstractHigh‐entropy alloys (HEAs) have offered wide opportunities for materials discovery, property optimization, and application exploration. In spite of some encouraging progress, manipulating HEAs with functional morphology/mesostructure and controlled chemical orderliness remains a big challenge. In this manuscript, a powerful and general strategy to synthesizing libraries of mesoporous high‐entropy intermetallics (MHEIs) with controlled orderliness in both mesoscopic and atomic levels is reported for the first time. Final products feature an ordered polyhedral morphology and double‐gyroid mesostructure as well as long‐range L10 intermetallic phase and HEA composition, delivering multiple advantages for enhancing electrochemical performance in oxygen reduction reaction (ORR) and single rechargeable zinc–air battery. Specifically, MHEI‐PtPdFeCoNi affords remarkable ORR activity (0.63 A mg−1 for mass activity and 1.01 mA cm−2 for specific activity) and superior stability (≈87% activity retained for 50 000 cycles and chronoamperometry tests) compared with the MHEAs with disordered atomic arrangement and commercial Pt/C. The excellent performance comes from the optimized surface HEA multimetallization as well as ordered intermetallic and mesoporous structure that changes the chemisorption of O*/OH* intermediates and lowers the overall energy barrier of oxygen reduction.
Accelerating charging dynamics using self‐driven optimizing porous structures
Authors: Huang Pan , Tao Haolan , Liu Honglai , Lian Cheng 
Published: December 2023

AbstractRelating the complex structures of electrodes to their charging dynamics is crucial for optimizing supercapacitors, which remains an experimental and theoretical challenge. Here, we construct a pore network model (PNM) that can be downward‐transformed into a well‐known transmission‐line model and a stack‐electrode model to describe the disordered porous structure of carbon‐based electrodes. A mathematical expression is derived using an equivalent circuit model of the PNM to quantify the relaxation times of the potential and concentration. The expression is then verified using numerical solutions based on the simplified Poisson–Nernst–Planck equations and experimental data. The structure of the PNM for experimental verification is directly extracted from a porous electrode reconstructed using a scanning electron microscopic image. A self‐driven optimization framework is proposed by coupling the derived expression with a genetic algorithm to generate an optimal porous structure that can be used to investigate the changing dynamics of the electrode. Our framework provides a general image–structure–performance optimization platform for understanding and accelerating charging dynamics in porous electrodes.
Synergy of carbanion siting and hydrogen bonding in super‐nucleophilic deep eutectic solvents for efficient CO2 capture
Authors: Chen Meisi , Xiong Wenjie , Chen Weida , Li Shangyu , Zhang Feng , Wu Youting 
Published: December 2023

AbstractCarbanion‐based ionic liquids are proposed and utilized as the key components for the construction of five super‐nucleophilic deep eutectic solvents (SNDESs) in the paper. The super‐nucleophilic nature of carbanion‐based ionic liquids (ILs) is found to enable the capture of CO2 with large absorption capacity. However, the absorption is very slow in the IL due to high viscosity. The synergy of carbanion siting and hydrogen bonding is found to enable high and fast absorption of CO2 in [N2222][CH(CN)2]‐ethylimidazole (Eim), and a synergistic absorption mechanism is proposed and validated from spectroscopic analyses and quantum calculations. The enthalpy change of CO2 absorption in [N2222][CH(CN)2]‐Eim is calculated to be −39.6 kJ mol−1 according to the thermodynamic model, and the moderate value implies that both absorption and desorption of CO2 in the DES are favored and well balanced. The carbanion and hydrogen bond mediated by SNDESs provides a novel insight into the efficient CO2 capture.
Structural insights into variation of intramolecular acid site using phase transition experiments and computation
Authors: Fu Dali , Wang Haodong , Wang Tan , Xu Chunming , Han Yehua 
Published: December 2023

AbstractMass transfer from liquid to gas phase is a crucial process in chemical engineering. Due to the heterogeneity and dynamic nature of the phase transition process, monitoring the structural changes of compounds during this process is challenging. In this work, a combining of the mass spectrometry‐based method and quantum chemistry calculations was used to study the structural changes during liquid‐to‐gas phase transitions. Electrospray is used to induce the transition of phenolic acid molecules from the liquid phase to the gas phase. The deprotonated structures were captured and separated using ion mobility mass spectrometry. Deprotonated structures helped to identify the most acidic functional group within the molecule. These deprotonated structures were confirmed by collision‐induced dissociation and molecular collision cross‐section measurements. Quantum chemistry calculations revealed the mechanisms about the variation of intramolecular acid site and “kinetic trapping.” Three liquid‐to‐gas phase transformation models were proposed, demonstrating that the variation in free energy among different deprotonated structures governs the thermodynamic/kinetic process of the liquid‐to‐gas phase conversion.
A case of MBTPS1‐related disorder due to compound heterozygous variants in MBTPS1 gene: Genotype–phenotype expansion and the emergence of a novel syndrome
Authors: Liaqat Khurram , Treat Kayla , Mantcheva Lili , Nasir Abdul , Weaver David D. , Conboy Erin , Vetrini Francesco 
Published: December 2023

AbstractMBTPS1 (NM_003791.4) encodes Site‐1 protease, a serine protease that functions sequentially with Site‐2 protease regulating cholesterol homeostasis and endoplasmic reticulum stress response. MBTPS1 pathogenic variants are associated with spondyloepiphyseal dysplasia, Kondo‐Fu type (MIM:618392; cataract, alopecia, oral mucosal disorder, and psoriasis‐like syndrome, and Silver–Russell‐like syndrome). In this report, we describe a 14‐year‐old female with a complex medical history including white matter volume loss, early‐onset cataracts, retrognathia, laryngomalacia, inguinal hernia, joint hypermobility, feeding dysfunction, and speech delay. Additionally, features of ectodermal dysplasia that she has include decreased sweating, heat intolerance, dysplastic nails, chronically dry skin, and abnormal hair growth issues. Exome sequencing analysis identified compound heterozygous variants in the MBTPS1 gene: c.2255G > T p.(Gly752Val) predicted to affect important function of the protein, which was inherited from the mother, and a splice site variant c.2831 + 5G > T, which was inherited from the father. The RNA‐seq analysis of the splice variant showed skipping of exon 21, predicted to result in frameshifting p.(Ser901fs28*) leading to non‐sense mediated decay. To our knowledge, only eight studies have been published that described the MBPTS1‐related disorders. Interestingly, we observed the features of ectodermal dysplasia in our patient that further expands the phenotypic spectrum of MBTPS1 gene‐related disorders.
Cross‐domain Chirality Transfer in Self‐Assembly of Chiral Block Copolymers
Authors: Yuan Jun , Chiu Po‐Ting , Liu Xiang , Zhou Jiajia , Wang Yingying , Ho Rong‐Ming , Wen Tao 
Published: December 2023

AbstractChirality transfer is essential to acquire helical hierarchical superstructures from the self‐assembly of supramolecular materials. By taking advantage of chirality transfers at different length scales through intra‐chain and inter‐chain chiral interactions, helical phase (H*) can be formed from the self‐assembly of chiral block copolymers (BCPs*). In this study, chiral triblock terpolymers, polystyrene‐b‐poly(ethylene oxide)‐b‐poly(L‐lactide) (PS‐PEO‐PLLA), and polystyrene‐b‐poly(4‐vinylpyridine)‐b‐poly(L‐lactide) (PS‐P4VP‐PLLA) are synthesized for self‐assembly. For PS‐PEO‐PLLA with an achiral PEO mid‐block that is compatible with PLLA (chiral end‐block), H* can be formed while the block length is below a critical value. By contrast, for the one with achiral P4VP mid‐block that is incompatible with PLLA, the formation of H* phase would be suppressed regardless of the length of the mid‐block, giving cylinder phase. Those results elucidate a new type of chirality transfer across the phase domain that is referred as cross‐domain chirality transfer, providing complementary understanding of the chirality transfer at the interface of phase‐separated domains.
An efficient and template‐free synthesis of mesoporous silica from coal fly ash
Authors: Liu Dandan , Qiao Huimin , Qin Shiyao , Xing Xin , Yan Kezhou 
Published: December 2023

AbstractIn the study, the desilication liquids and acid‐leached residues derived from the “alumina extraction process” of coal fly ash (CFA) were used as raw materials to prepare sodium silicate precursor. Then, the mesoporous silica with controllable pore structure properties was synthesized by an efficient, template‐free process from obtained sodium silicate. The effect of the sodium silicate properties and synthesis conditions on the pore structure properties of disordered mesoporous silica were investigated. The resulting material was characterized by N2 adsorption–desorption, scanning electron microscopy (SEM), and transmission electron microscopy (TEM) and tested as an adsorbent for removal of lead ions (Pb2+). The results showed that the precursor with high modulus (3.0) and concentration (60 g·L−1) was beneficial for the synthesis of mesoporous silica with high specific surface area. The mesoporous silica with specific surface area of 690 m2·g−1 and pore volume of 1.28 cm3·g−1 was synthesized at mild aging temperature (40°C) and pH value of 8. Moreover, the materials possessed an adsorption capacity of 303 mg·g−1 for lead ions after amino modification. The adsorption efficiencies for lead ions were maintained at ~90% after five recovery cycles. Overall, the utilization efficiency of SiO2 in CFA reached up to 93%.
Interface, thermal, and Fourier transform—infrared spectroscopy investigation on polylactic acid/polyhydroxyalkanoate composites with silane‐treated aluminum particles and intercalated montmorillonite inclusions for semiconductor devices
Authors: Shanmugasundram HariprashanthPalaniVelayuda , Jayamani Elammaran , Soon Kok Heng 
Published: December 2023

AbstractIn this investigation, the dielectric properties of silane‐influenced aluminum conductive particles in polylactic acid, polyhydroxyalkanoates, and intercalated montmorillonite (MMT) composite were assessed for enhancing the dielectric constant, dielectric loss, and AC conductivities. Eight different sets of samples were fabricated with untreated and silane‐treated batches of biopolymer composites where the highest recorded dielectric constant was 3.98 at relaxation frequency of 10 kHz. One of the notable observations in the dielectric loss was with PLA/PHA/iMMT/Al (10 wt%) (silane‐treated) composites exhibited the lowest losses past relaxation frequencies. Furthermore, FT‐IR spectra were conducted on the samples to identify stretching and bonds created by silane and aluminum particles. The IR spectra confirm the formation of the SiOAl bond when treated with 3‐glycidyloxypropyl‐trimethoxysilane (GPTMS) solution and confirm the bond of AlOH hydroxyl bonds in the untreated composite samples. Other IR spectra information that was gathered would include carbonyl group stretching at 1750 cm−1 and absorption bands of hydroxy acids, between 3511 and 3640 cm−1, respectively. Scanning electron microscopy was performed on the sample to observe the formation of matrix cracks and exfoliation. A rough surface can be seen on PLA/PHA blends and the crystallization of these polymer blends regions can be vividly seen from the micrographs. Lastly, thermogravimetry analysis on the composite samples shows a predominant mass loss at 300°C before complete degradation and the notable composite with the lowest mass loss would be PLA/PHA/iMMT/Al (10 wt%) (ST) composite samples and with the inclusion of a constant 5 wt% organoclay MMT fillers imposed a high‐onset degradation temperature, which was remarkable for composites that were fabricated through standard hot‐press compression molding and cooling procedures.
Phosphorus‐containing benzoxazine modified epoxy resin: High flame retardancy, low dielectric, and low water absorption
Authors: Liu Jiuhong , Liu Jie , Yu Guangrui , Li Yueqiu , Yu Qing , Han Yuxi , Wang Zhongwei , Hou Jijin 
Published: December 2023

AbstractA phosphorous‐containing benzoxazine, (3‐(4‐hydroxyphenyl)‐3,4‐dihydro‐2H‐benzo[e][1,3]oxazin‐4‐yl)diphenylphosphine oxide (DPOBH), was synthesized and used as flame retardant and co‐curing agent in the presence of 4,4′‐diaminodiphenylsulfone (DDS) for diglycidyl ether of bisphenol‐A (DGEBA) epoxy resin. The flame retardancy, thermal stability, Tg, dielectric properties, and water absorption properties of epoxy resins (EP) were investigated and compared. The incorporation of DPOBH results in ca. 40%–45% increase of limiting oxygen index (LOI) values. UL‐94 V‐0 rating could be achieved for EP/DPOBH1.2 sample with the LOI value of 35.1%. Compared with EP, ca. 47% decrease of peak heat release rate (PHRR) could be obtained for EP/DPOBH1.2. According to the results of cone calorimetry tests (CCT), DPOBH could play roles in both gas and condensed phases. Moreover, the incorporation of DPOBH could reduce the water absorption rate, dielectric constant, and dielectric loss. All results suggest that DPOBH is a type of flame retardant suitable for EP used in electronic fields.
Generalized Perturbation Theory for Weakly Deformed Microdisk Cavities
Authors: Zhang Xuenan , Liu Bin , Zhou Xue , Yan Xin , Wang Fang , Yu Zongfu , Cheng Tonglei 
Published: December 2023

AbstractA perturbation treatment is derived for weakly deformed microdisk cavities in a more generalized scenario, where both resonant and non‐resonant surface scattering processes coexist. It is proved that the originally developed nondegenerate and degenerate perturbation theories are simplified forms of the generalized theory in special cases. The validity of the perturbation theory is verified by the comparison with a full numerical method for two generic classes of deformed microdisk cavities: locally notched microdisks and smooth globally deformed microdisks. The simulation of these two classes of microdisk cavities using the perturbation theory unveils the distinct characteristics of optical modes from the ones predicted by the original nondegenerate and degenerate perturbation theories in the generalized scenario. Furthermore, a hybrid‐scattering‐based exceptional point is introduced for deformed microdisk cavities in the generalized scenario by using the perturbation theory. The exceptional point exhibits higher nonorthogonality over the originally proposed resonant‐scattering‐based exceptional point, as non‐resonant scattering processes provide an additional degree of freedom. Full numerical simulations demonstrate that the exceptional point is more robust against random surface roughness at cavity boundary than the resonant‐scattering‐based exceptional point.
Circularly Polarized Luminescence from Schiff‐base [4]Helicene Boron Complexes
Authors: Ikeshita Masahiro , Watanabe Shinya , Suzuki Seika , Kitahara Maho , Imai Yoshitane , Tsuno Takashi 
Published: December 2023

AbstractBoron complexes with Schiff‐base [4]helicene ligands were synthesized. These complexes were characterized by NMR spectroscopy and their helical molecular structures were unequivocally established by X‐ray diffraction (XRD) analysis. The helical boron complexes exhibited efficient photoluminescence under UV irradiation, and the circularly polarized luminescence (CPL) properties were investigated for optically pure samples. Density functional theory (DFT) calculations were conducted to further understand their photophysical properties including chiroptical responses.
Lignin activated carbon obtained by a environmentally friendly green production process using deep eutectic solvents
Authors: Aydemir Deniz , Ergun Mehmet Emin , Gulsoy, Sezgin Koray , Ozan Zeynep Eda , Gunduz Gokhan 
Published: December 2023

AbstractThe aim of this study was to produce activated carbon (AC) from lignin obtained with deep eutectic solvents (DESs) of choline chloride–lactic acid. For this, lignin particles were produced using the DES. The DES lignin (DES‐Lig) was modified with zinc dichloride, and the lignin activated carbon (lig‐AC) was produced by carbonization at 600 and 900 °C. In this study, the AC obtained from the commercial lignin was also used to determine the changes in the lig‐AC from the lignin obtained with the DES. The material properties were investigated using Brunauer–Emmett–Teller (BET) surface analysis, scanning electron microscopy (SEM) and thermogravimetric analysis (TGA), and the structural properties were investigated with X‐ray diffractometry (XRD) of the lig‐ACs. The commercial and DES‐Lig exhibited different microscopic morphologies. The surface area of the samples generally ranged from 504 to 698 g/cm2, and they included both micro‐ and mesopores according to SEM characterization. The XRD analysis showed that the ACs obtained have an amorphous structure, and thermogravimetric analysis of the ACs exhibited similar thermal behavior to that in the literature. The best morphological structure was found in the ACs prepared from lignin with the DES at 900 °C according to the results of SEM, TGA, XRD and BET analysis. The proximate analysis showed that the best ACs contain 1.5% moisture, 6.5% volatile matter, 5.5% ash content and 86.5% fixed carbon. According to the elemental analysis, the amounts of essential elements, including C, H, N and O were investigated, and the best activated carbon was determined to be the DES‐Lig at 900 °C according to BET and the proximate fixed carbon results.
Significance of the anterior cingulate cortex in neurogenesis plasticity: Connections, functions, and disorders across postnatal and adult stages
Authors: Naffaa Moawiah M. 
Published: December 2023

AbstractThe anterior cingulate cortex (ACC) is a complex and continually evolving brain region that remains a primary focus of research due to its multifaceted functions. Various studies and analyses have significantly advanced our understanding of how the ACC participates in a wide spectrum of memory and cognitive processes. However, despite its strong connections to brain areas associated with hippocampal and olfactory neurogenesis, the functions of the ACC in regulating postnatal and adult neurogenesis in these regions are still insufficiently explored. Investigating the intricate involvement of the ACC in neurogenesis could enhance our comprehension of essential aspects of brain plasticity. This involvement stems from its complex circuitry with other relevant brain regions, thereby exerting both direct and indirect impacts on the neurogenesis process. This review sheds light on the promising significance of the ACC in orchestrating postnatal and adult neurogenesis in conditions related to memory, cognitive behavior, and associated disorders.
Characterization of an oligometastatic state in patients with metastatic pancreatic adenocarcinoma undergoing systemic chemotherapy
Authors: de Ortiz de Choudens Saryleine , Visotcky Alexis , Banerjee Anjishnu , Aldakkak Mohammed , Tsai Susan , Evans Douglas B. , Christians Kathleen K. , Clarke Callisia N. , George Ben , Shreenivas Aditya , Kamgar Mandana , Chakrabarti Sakti , Dua Kulwinder S. , Khan Abdul Haq , Madhavan Srivats , Erickson Beth A. , Hall William A. 
Published: December 2023

AbstractPurpose/ObjectivesMost patients with pancreatic adenocarcinoma (PDAC) will present with distant metastatic disease at diagnosis. We sought to identify clinical characteristics associated with prolonged overall survival (OS) in patients presenting with metastatic PDAC.Materials/MethodsPatients presenting with metastatic PDAC that received treatment at our institution with FOLFIRINOX or gemcitabine‐based chemotherapies between August 1, 2011 and September 1, 2017 were included in the study. Metastatic disease burden was comprehensively characterized radiologically via individual diagnostic imaging segmentation. Landmark analysis was performed at 18 months, and survival curves were estimated using the Kaplan–Meier method and compared between groups via the log‐rank test. ECOG and Charlson Comorbidity Index (CCI) were calculated for all patients.Results121 patients were included with a median age of 62 years (37–86), 40% were female, 25% had ECOG 0 at presentation. Of the 121 patients included, 33% (n = 41) were alive at 12 months and 25% (n = 31) were alive at 18 months. Landmark analysis demonstrated a significant difference between patients surviving <18 months and ≥18 months regarding the presence of lung only metastases (36% vs. 16%, p = 0.04), number of organs with metastases (≥2 vs. 1, p = 0.04), and disease volume (mean of 19.1 cc vs. 1.4 cc, p = 0.04). At Year 1, predictors for improved OS included ECOG status at diagnosis (ECOG 0 vs. ECOG 1, p = 0.04), metastatic disease volume at diagnosis (≤0.1 cc vs. >60 cc, p = 0.004), metastasis only in the liver (p = 0.04), and normalization of CA 19‐9 (p < 0.001). At Year 2, the only predictor of improved OS was normalization of the CA 19‐9 (p = 0.03). In those patients that normalized their CA 19‐9, median overall survival was 16 months.ConclusionsIn this exploratory analysis normalization of CA‐19‐9 or volumetric metastatic disease burden less than 0.2 cc demonstrated a remarkable OS, similar to that of patients with non‐metastatic disease. These metrics are useful for counseling patients and identifying cohorts that may be optimal for trials exploring metastatic and/or local tumor‐directed interventions.