bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two Birds with One Stone: Drug Regime Targets Viral Pathogenesis
Phases and COVID-19 ARDS at the Same Time
Authors: Ghavami Ghazaleh , Sardari Soroush 
Published: January 2024

Background:
Severe COVID-19 or severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) is a kind of viral pneumonia induced by infection with the coronavirus that
causes ARDS. It involves symptoms that are a combination of viral pneumonia and ARDS. Antiviral or immunosuppressive medicines are used to treat many COVID-19 patients. Several
drugs are now undergoing clinical studies in order to see if they can be repurposed in the future.

Material and Methods:
In this study, in silico biomarker-targeted methodologies, such as target/molecule virtual screening by docking technique and drug repositioning strategy, as well as
data mining approach and meta-analysis of investigational data, were used.

Results:
In silico findings of used combination of drug repurposing and high-throughput docking methods presented acetaminophen, ursodiol, and β-carotene as a three-drug therapy regimen
to treat ARDS induced by viral pneumonia in addition to inducing direct antiviral effects
against COVID-19 viral infection.

Conclusion:
In the current study, drug repurposing and high throughput docking methods have
been employed to develop combination drug regimens as multiple-molecule drugs for the therapy of COVID-19 and ARDS based on a multiple-target therapy strategy. This approach offers
a promising avenue for the treatment of COVID-19 and ARDS, and highlights the potential
benefits of drug repurposing in the fight against the current pandemic.
Artificial Intelligence (AI) Generated Health Counseling For
Mental Illness Patients
Authors: M Shankar Ganesh , N Venkateswaramurthy 
Published: January 2024

Background:
Mental illness remains a global public health concern, affecting
millions of individuals worldwide. However, barriers such as limited access to mental
healthcare, stigma, and resource constraints hinder effective interventions and treatment.
The fourth industrial age, marked by the integration of artificial intelligence technologies,
offers innovative solutions to revolutionize mental health counseling and support.

Method:
This review explores the challenges faced in traditional mental healthcare and
proposes the integration of AI-generated health counseling as a transformative approach.
AI-powered chatbots and virtual assistants present accessible, cost-effective alternatives
that overcome geographical barriers and combat stigma. These chatbots employ natural
language processing and machine learning to engage users in personalized and interactive
conversations. Chatbots also offer continuous support, psychoeducation, and coping strategies.
Virtual Reality Therapy leverages AI to create realistic simulations for exposure therapy,
proving effective in treating anxiety disorders and PTSD. AI-driven voice assistants
and virtual coaches enhance mental health counseling by delivering behavioral therapy and
improving symptoms of depression and anxiety.

Results:
They enhance accessibility, provide 24/7 support, and reduce stigma, offering
personalized support tailored to individual needs. Integrating AI-generated health counseling
in mental healthcare can bridge treatment gaps, improve accessibility, and strengthen
the patient-provider relationship.

Conclusion:
AI serves as a valuable supplement, working collaboratively with human
therapists to provide comprehensive care. Embracing AI technologies responsibly holds
promise for the future of mental health counseling and offers transformative possibilities to
address the global burden of mental illness.
A Flexible Reference Array Electrode Technique for In Situ Imaging the Corrosion of Q235 Carbon Steel Welded Joints
Authors: Zuo Juan , Ma Lu , Chen Ajiao , Lin Liwen , Lin Changjian , Zhang Houan 
Published: January 2024

Introduction:
Localized corrosion in welds has always been a very common
and difficult problem in many industrial fields. Preferential corrosion usually
occurs in the weld zones with irregular shapes of metal welds due to the welding process.

Methods:
To address the challenge of monitoring corrosion behavior at the weld zone
in real-time, a novel Ag/AgCl flexible array, arranged in a 4×8 electrode configuration,
has been developed. This array is employed for in situ monitoring of the corrosion
process in Q235 steel welded joints (including single butt welds, double butt
welds, and fillet welds) immersed in a 0.01 mol/L NaCl solution with a pH of 9. The
measurement is conducted using a custom-made array electrode signal test system.

Results:
The results demonstrate that the prepared electrode exhibits a highly responsive
behavior to chlorine ions from 0.001 to 0.1 mol/L concentration and maintains
excellent stability during 4000s. The weld zone shows higher corrosion activity and
trends to generate pitting corrosion for all three welded joints in the first 15 min. With
the increase of time, micro pitting corrosion dissolves and expands to macro point
corrosion in the next 30 min.

Conclusion:
The flexible reference array electrode proves to be a powerful tool for
the in situ monitoring of carbon steel corrosion, offering a comprehensive depiction
of the steel's corrosion status over time. Such insights are crucial for making accurate
corrosion predictions and conducting service life evaluations of steel structures.
Nutraceuticals Health Benefits in Cancer
Authors: Saha Sunam , Kumar Shivendra , Sharma Bhawna , Mishra Shuchita , Singh Shubham , Chaturvedi Arun Kumar , Patel Ravindra , Agrawal Mohit 
Published: January 2024

Abstract:
Cancer is one of the leading causes of death worldwide, with multiple pathological components.
Genetic abnormalities, infection or inflammation, poor diet, radiation exposure, work
stress, and/or ingestion of toxic substances have all been associated with cancer development and
progression. Early detection and treatment of cancer have been shown to increase the chances of
survival and recovery and reduce the side effects of anticancer drugs. Anticancer drugs continue to
cause negative side effects that negate treatment benefits in terms of hospitalization and survival.
Many naturally occurring bioactive compounds are shown to have anticancer properties. That is,
they can eliminate altered and cancer cells without harming their healthy counterparts. In particular,
the following activities have been reported to support nutrition during cancer treatment: cell growth
inhibition, antioxidant activity, anti-inflammatory activity, and minimized negative effects due to
natural antioxidants. Keeping the side effects minimum helps patients adhere to anticancer therapy.
Among currently available anticancer agents, dietary supplementation can be considered in conjunction
with current chemotherapy to improve response and compliance in cancer patients. However, it
should be noted that before discussing data from studies on bioactive plant supplements, it is important
to ensure that the tests were performed according to protocol.
Managing Postharvest Losses of Vegetables and Fruits: A Methodological
Review
Authors: De Sourav , Banerjee Subhasis , Banerjee Sabyasachi 
Published: January 2024

Abstract:
Vegetables and fruits are highly perishable agricultural commodities cultivated all
over the world. However, inadequate handling practices have led to significant postharvest losses
of these agricultural commodities, as well as the wastage of valuable resources, such as time
and money. Hence, it can be observed that cultivators often experience significant financial setbacks
as a result of inadequate comprehension regarding the nature and origins of these losses,
insufficient preservation practices, and ineffective approaches to transportation and marketing.
In addition, the utilization of suitable chemical agents during both the pre- and postharvest
phases has the potential to prolong the shelf life of agricultural products. This preservation technique
safeguards vegetables and fruits from pathogenic organisms and other forms of environmental
harm, thereby enabling their availability for an extended duration. Therefore, this review
proposes a methodology for managing fruits and vegetables postharvest to minimize losses and
optimize returns.
Enhancement of Wheat (Triticum aestivum L.) Growth and Yield Attributes in a Subtropical Humid Climate through Treated Ganga Sludge-based Organic Fertilizers
Authors: Balkrishna Acharya , Sharma Nidhi , Gautam Ajay Kumar , Arya Vedpriya , Khelwade Vikram 
Published: January 2024

Background:
Sewage sludge is a by-product of urbanization that poses environmental
and health challenges. However, it can also be a valuable source of organic matter and nutrients
for agriculture.

Method:
This study aimed to assess the potential of five types of organic fertilizers derived from
treated Ganga sludge on the growth of wheat plants. The Patanjali Organic Research Institute
has developed five types of granulated organic fertilizer from the stabilized Ganga sludge.

Results:
The results showed that the organic fertilizers significantly improved the wheat performance
in terms of plant height, biomass accumulation, chlorophyll content, leaf area and other
yield parameters. Furthermore, the fertilizers ameliorated soil physicochemical attributes and
augmented the availability of macro- and micronutrients. Importantly, levels of heavy metals in
soil and wheat grains remained within permissible limits, affirming the safety and appropriateness
of these fertilizers for wheat cultivation.

Conclusion:
This study underscores the efficient utilization of treated Ganga sludge as a valuable
organic fertilizer source, proposing a sustainable and ecologically sound approach for sewage
sludge management and enhancement of agricultural productivity.
Growth performances of seed sources in a progeny trial of Pinus brutia Ten.
Authors: Bilir Nebi , Ozbey Alper Ahmet 
Published: January 2024

Progeny trial is a scientific plantation established for different forestry purposes such as selection and establishment of seed sources. Tree height and diameter at breast height were examined in a 23-year-old progeny trial established by seedlings of five seed orchard populations and five seed stand populations which were mother/base populations of the orchards in Turkish red pine (Pinus brutia Ten.) to compare the seed sources for the traits in this study. Trees of seed orchard populations showed higher growth performances than that of seed stand populations for the traits. Most of the seed stand populations had higher tree height than their seed orchard populations opposite to diameter at breast height. While seed sources were similar (p>0.05), populations showed significant (p<0.05) differences for both traits according to results of analyses of variance. Tree height was more homogenous than diameter at breast based on Duncan’s multiple range tests and coefficients of variations. Positive and significant correlation (p<0.05) was found between the traits in both seed stand populations and seed orchard populations.
Potential of new planting container in Quercus robur seedlings production – first report
Authors: Mijatovic Ljubica , Pavlović Slavko , Jović Lidija , Devetaković Jovana , Vilotić Dragica 
Published: January 2024

Container production of forest seedlings needs constant improvement, so in the aim to test the new container type this research was conducted. Quercus robur seedlings were produced in the container made of natron paper and compared with seedlings produced in commonly used container types in Serbia. Q. robur seeds were sown in the first week of November 2020 in a total of 30 containers (10 of each type). After the first growing season in the nursery, on November 2021, seedlings’ morphological parameters (root collar diameter - RCD, height - H, dry weight of shoot (SDW) and root (RDW), seedling dry weight (SLDW), shoot to root ratio (S:R), sturdiness coefficient (SQ), dry weight of lateral roots (LRDW), percent of lateral roots (%LR), Dickson’s quality index (QI), root-bound index (RBI) as RBI-diameter and RBI-volume, and rooting intensity (ROIN)) were compared using one-way ANOVA. Seedlings produced in the new container showed better morphological parameters such as H, SQ, SDW, RDW, SLDW, LRDW, QI and ROIN. Differences of seedlings from different containers were not detected for H, RCD, SQ, SDW, %LR, RBI-diameter, so we can conclude that seedlings produced in the new container type are similar with other container seedlings. Larger volume of these cells indicate use for Quercus species which have strong roots. Results obtained from the nursery promote use of the new container in forest seedlings production and testing at the field.
Toxic Relationships Described by People With Breast Cancer on Reddit: Topic Modeling Study
Authors: Davidson Cara Anne , Booth Richard , Jackson Kimberley Teresa , Mantler Tara 
Published: January 2024

Background
Social support is essential to promoting optimal health outcomes for women with breast cancer. However, an estimated 12% of women with breast cancer simultaneously experience intimate partner violence (IPV; physical, psychological, or sexual abuse by an intimate partner). Women who experience IPV during breast cancer may lack traditional social support, and thus seek out alternative sources of support. Online community forums, such as Reddit, can provide accessible social connections within breast cancer–specific communities. However, it is largely unknown how women with breast cancer use Reddit to describe and seek support for experiences of IPV.

Objective
This study aims to explore how patients with breast cancer describe toxic relationships with their partners and immediate family members on Reddit.

Methods
This exploratory, cross-sectional, topic-modeling study analyzed textual data from 96 users in the r/breastcancer subreddit in February 2023. The meaning extraction method, inclusive of principal component analysis, was used to identify underlying components. Components were subjected to sentiment analysis and summative content analysis with emergent categorical development to articulate themes.

Results
Seven themes emerged related to toxic relationships: (1) contextualizing storytelling with lymph nodes, (2) toxic behavior and venting emotions, (3) abandonment and abuse following diagnosis, (4) toxic relationships and social-related fears, (5) inner strength and navigating breast cancer over time, (6) assessing social relationships and interactions, and (7) community advice and support. Toxic relationships were commonly characterized by isolation, abandonment, and emotional abuse, which had profound emotional consequences for patients. Reddit facilitated anonymous venting about toxic relationships that helped patients cope with intense feelings and stress. Exchanging advice and support about navigating toxic relationships during breast cancer were core functions of the r/breastcancer community.

Conclusions
Findings emphasized the value of Reddit as a source of social support for patients with breast cancer experiencing toxic relationships. Clinicians who understand that many patients with breast cancer experience toxic relationships and considerable psychological sequelae are better prepared to support their patients’ holistic well-being. Further investigation of Reddit as a possible resource for advice, information, and support has the potential to help inform clinical practice and subsequently, patient health outcomes.
Археологические коллекции, сформированные по результатам раскопок на территории Калмыкии, как источник по истории раннего железного века
Authors:   Kalmyk Scientific Center of the RAS (8, Ilishkin St., 358000 Elista, Russian Federation), Kekeev Erdni A. 
Published: January 2024

Introduction. Archaeological collections of the Early Iron Age, formed by the results of excavations on the territory of the Republic of Kalmykia, are currently stored in museums in Russia: The National Museum of the Republic of Kalmykia named after N. N. Palmov (Elista), the Saratov Regional Museum of Local Lore (Saratov), the State Historical Museum (Moscow), as well as in several public museums of Kalmykia. Goals. The purpose of the article is to analyze archaeological collections from the monuments of the Republic of Kalmykia as a source in the history of the Early Iron Age. The progress of the work. The analysis was carried out, during which the finds of the Early Iron Age were considered by origin, material of manufacture, categories of inventory, use in museum exhibitions, and the degree of their introduction into scientific circulation. Results. It has been established that the funds of these museums contain almost 1,500 units of horseradish, which originate from funerary monuments. The study of the distribution of finds by material of manufacture showed that most of the objects are made of clay — 37.4%, bronze — 19.5% and iron — 18.1%, Objects of this period can be divided into three main categories of funeral equipment: tableware (mainly clay, less often metal), weapons and elements of horse harness, personal objects and decorations. An analysis of the relevance of the studied objects of the Early Iron Age showed that finds from Kalmykia are rarely used in museum and exhibition work and are part of the permanent exhibition only in the National Museum of the Republic of Kalmykia.
Credibility of Information in the Unified State Register of Real Property. Specifics of Correcting the Data by Implementing the System of Integrated Cadastral Works
Authors: Tikhonova Kseniya V. , Lapshina Kseniya A. , Ermachenko Darya D. 
Published: January 2024

The problem of incomplete information presented in the Unified State Register of Real Property (USRRP) and issues referring to the registry errors in the information entered in the Unified State
Register of Real Property, the procedure for correcting thereof, the need of implementing the new methods of forming and correcting the information in the Unified State Register of Real Property are
being investigated. Alongside, the initiative to optimise the state services provision in the frame of the “National Spatial Data System” programme, which is aimed at future integration of the information about the real estate objects, property rights for them, cadastral valuation and other features, is analysed. The aims for implementation of such a system have been sorted out, namely, the formation and implementation of the digital geospatial maintenance, ensuring the completeness and
credibility of information in the USRRP, enhancing quality of the state and other services provided by the Federal Service for State Registration, Cadastre and Cartography (Rosreestr).
Menntun eða þjónusta?
Authors: Jóhannesson Ingólfur Ásgeir , Símonardóttir Sunna 
Published: January 2024

Mikil fjölmiðlaumræða varð um leikskóla á árunum 2020–2022. Þann 14. janúar 2020 samþykkti meirihluti skóla- og frístundaráðs Reykjavíkurborgar að stytta opnunartíma leikskóla um hálftíma síðdegis, hafa skólana opna til 16:30 í stað kl. 17. Við greindum umræðuna næstu 13 daga á eftir. Einnig voru greindir kosningapistlar fyrstu 13 dagana í maí 2022 fyrir sveitarstjórnarkosningarnar 14. maí 2022. Samtals voru þetta 59 greinar, fréttir og pistlar. Leitað var svara við spurningunum: Hvað er leikskóli og til hvers er hann? Hvað er ætlast til að börn fái út úr leikskóladvöl?
Við greindum efnið með sex þrepa aðferð sögulegrar greiningar á orðræðu. Við greindum sex þrástef í efninu; álagið á börnin, álagið á starfsfólkið, þroski og leikur, jafnrétti, þjónustuhlutverk leikskóla og loks þema sem við nefnum skjótvirkar lausnir. Við greindum tvö löggildingarlögmál sem jafnframt fela í sér þversagnir. Hið fyrra felur í sér að leikskóli er menntastofnun sem um leið hefur samfélagsleg hlutverk, annars vegar til að stuðla að jafnrétti kynjanna og hins vegar sem þjónusta við atvinnulífið með því að sjá til þess að börnin séu á öruggum stað meðan foreldrarnir vinna. Þversögn felst í að ýmis ytri skilyrði hafa orðið til þess að leikskólunum er erfitt að sinna þessu verkefni, það er að börnin fái sveigjanlegt heils dags leikskólapláss. Hitt lögmálið er að flestir virðast vilja að leikskólar sem menntastofnanir séu ólíkir grunnskólum. Sókn í að stytta dvalartíma og stytta opnunartíma kemur ef til vill ekki niður á menntunarhlutverkinu en rekst á við jafnréttis- og þjónustuhlutverkið við foreldra og atvinnulíf.
Rannsóknin gefur skýrt til kynna að tekist er á um framtíð leikskólakerfisins á Íslandi. Höfundar undirstrika mikilvægi þess að uppbygging leikskólakerfisins taki mið af fjölþættum hlutverkum hans í íslensku samfélagi, þar sem virðing er borin fyrir þeim öllum.
Parallelization of the Traveling Salesman Problem by Clustering its Nodes and Finding the Best Route Passing through the Centroids
Authors: Romanuke Vadim 
Published: January 2024

AbstractA method of heuristically solving large and extremely large traveling salesman problems is suggested. The solver is a specific genetic algorithm producing approximately shortest routes the fastest of known heuristics without losing much in accuracy. The method consists in parallelizing the problem by clustering its nodes and finding the best route passing through the centroids of the clusters. The open-loop subroutes of the clusters are connected via specific nodes. These specific nodes referred to as connectors are determined as those for which the distance to the depot is maximal and the distance to the cluster of the following subproblem is minimal. Thus, a bunch of smaller open-loop problems is solved instead of solving the whole (closed loop) problem. Extremely large problems should be clustered manually by imposing a mesh of rotated square cells. In this case, the connectors should be determined manually as well. A connector can also be approximated by a node which is the closest to the line connecting the centroids of the two clusters. The suggested parallelization can produce a very significant speedup depending on how many processor cores are simultaneously available. The factual speedup by the parallelization depends on the availability of processor cores, memory, and the processor clock frequency. The efficiency of the parallelization is maintained for a few hundred to a few million nodes by any number of clusters being less than the size of the average cluster.
ETI-MAC: An Energy-Harvested Transmitter-Initiated MAC Protocol for Wireless Sensor Networks
Authors: Bengheni Abdelmalek 
Published: January 2024

AbstractThe paper proposes an Energy-Harvested Transmitter-Initiated MAC Protocol for WSNs (ETI-MAC). ETIMAC takes advantage of the benefits of transmitter-initiated schemes and employs the low power listening (LPL) method with small preamble messages so that each sensor node in the network can predict its next sleep duration based on the harvested energy rate value, thereby lowering the duty cycle by making use of its accumulating residual energy. The simulation results show that the proposed protocol outperforms compared to the old PSEHWSN scheme.
Building English – Punjabi Aligned Parallel Corpora of Nouns from Comparable Corpora
Authors: Kaur Dilshad , Singh Satwinder 
Published: January 2024

Abstract
Comparable corpora are the right resources for extracting parallel data due to their abundant availability. It is of great importance where parallel data are scarce. In this study, the focus is placed on building of parallel data for Punjabi and English language pair. The raw data were collected from web contents of “Mann Ki Baat”, which is a collection of textual speeches of Prime Minister of India Mr. Narendra Modi broadcasted every last Sunday of the month. Data were cleaned and pre-processed using a natural language toolkit. An alignment model using BERT was built that aligned two textual files on a sentence level. Furthermore, extraction of noun forms with the help of NLTK library in Python programming was performed. The noun aligned dataset was built for English-Punjabi language pair and made available at Mendeley data repository.