bluuebunny/crossref_metadata_2025_split huggingface dataset:
Weight method for determination of soluble β-glucans in barley grain
Authors: Popov V. S. , Konarev A. V. , Kovaleva O. N. , Konkova N. G. , Khoreva V. I. 
Published: January 2024

Background. Barley (Hordeum vulgare L.) is an important source of nutrients, such as starch, protein, and various dietary fibers. β-Glucans are soluble fibers found in high amounts in oat and barley grain, so they are becoming increasingly interesting due to their numerous functional and bioactive properties. The increased interest in β-glucans as a dietary supplement and a functional component of food calls for a convenient, inexpensive and affordable method for quantitative determination of these compounds.Materials and methods. An overview is given on the existing techniques for determining and isolating β-glucans in cereals: IR spectroscopy, enzymatic, colorimetric, and alkaline-enzymatic methods. Their advantages and disadvantages are shown. The disadvantages of the methods considered include high costs of reagents and equipment, duration of performance, and labor intensity.Results. This study promotes the weight method for isolation and quantitative determination of β-glucans in the grain of covered and naked barley. It is based on the modified alkaline method adapted to barley; we developed it earlier for oat grain. The amount of β-glucans in the grain of the studied barley accessions ranged from 4.12±0.23% to 5.34 ± 0.31% for naked cultivars, and from 3.57 ± 0.18% to 4.29 ± 0.32% for covered ones.Conclusion. Based on the conducted research, optimal conditions for the isolation and quantitative determination of β-glucans from barley grain were selected: centrifugation modes, temperature and extraction ratio, concentration of compounds, precipitation and drying procedures. The main advantage of the described method is its accessibility and practical applicability when conducting mass analysis, including studying a collection of cereal crops.
Ranking of spring bread wheat genotypes according to the heading date and growing season duration in different ecogeographic environments
Authors: Novikova L. Yu. , Zuev E. V. , Brykova A. N. 
Published: January 2024

Background. Adaptation of spring bread wheat cultivars to climate change requires a study of the factors affecting the length of their growing season in various environments. An attempt is made to analyze regularities in the effect of ecogeographic conditions on the correlations shown by the duration of the growing season and interphase periods in spring bread wheat genotypes.Materials and methods. Correlation coefficients were studied for the impact of the environment and temperature on the duration of the interphase periods from sprouting to heading (SH) and from heading to yellow ripeness (HR) versus the period from sprouting to yellow ripeness (SR) in VIR’s wheat collection across 18 sites located in Russia and Uzbekistan from 41 to 60°N and from 30 to 135°E. The effect of the genotype and year on SH and HR was studied, and agrometeorological regression models of SH and HR were constructed, based on the data obtained during the studies of the collection in St. Petersburg in 1945–2021.Results. For the sites below 52–54°N, the SR/SH correlation coefficient was generally higher than SR/HR, and in the upper latitudes it was vice versa. The change in the ratio of coefficients occurred due to an increase in the interannual variability of HR at lower temperatures. The effect of HR on SR became greater than that of SH at temperatures below 18°С during HR. The data of a long-term study in St. Petersburg demonstrated that the effect of the genotype on SH was 18.9%, with 68.9% of the year, and the effect of the factors on HR was 4.1 and 71.3%, respectively. Regression models showed that HR was determined by temperature for at least 81%, while SH had a lower coefficient of determination by weather (56%).Conclusion. Ranking of wheat genotypes according to their heading time reflected their differentiation in earliness. A significant contribution of HR was conspicuous under temperatures below 18°C after heading at latitudes above 52–54°N.
Studying self-fertility in new black currant cultivars from the VIR collection in Northwestern Russia
Authors: Tikhonova O. A. 
Published: January 2024

Background. An important task is to search for and select highly self-fertile cultivars for plant breeding programs and for setting single-cultivar plantings in commercial horticulture.Materials and methods. Cultivars were assessed for their self-fertility levels at Pushkin and Pavlovsk Laboratories of VIR in 2019–2022. Thirty black currant cultivars of eight genetic groups served as the research material. Their levels of self-fertility were tested using conventional techniques. Free pollination served as the control. The resulting data were analyzed according to the main indicators crucial for precise characterization of a cultivar’s self-fertility level: fruit setting rate, berry weight, seed yield, and fertilization effectiveness. The data were statistically processed using Microsoft Excel and the guidelines by B. A. Dospekhov. Fruit setting rate, berry weight, seed yield and fertilization effectiveness were considered for each pollination variant.Results and conclusion. Cultivars with high and stable self-fertility levels were identified as potential valuable sources for breeding programs: ‘Partizanka Bryanskaya’ (k-45548), ‘Ben Gairn’(k-45524), ‘Litvinovskaya’ (k-45542), ‘Mushketer’ (k-45544), ‘Raduzhnaya’ (k-45549), ‘Ben Lomond’ (k-32611), and ‘Vertikal’ (k-45528). Cvs. ‘Partizanka Bryanskaya’ (k-45548), ‘Ben Gairn’ (k-45524), ‘Mushketer’ (k-45544), and ‘Vertikal’ (k-45528) may be used in single-cultivar plantings because they are able to set the same number of berries under natural self-pollination and free pollination. Natural self-pollination (autogamy) led to a decrease in the size of berries and the number of seeds in them. An increase in the main self-fertility indicators was observed under artificial self-pollination and free pollination.
The role of perceived responsibility in patient complaint management
Authors: Ghrab Hatem , Baaziz Mohamed , BEN ABDERRAHMAN Abderraouf , Sariati Dorsaf Sariati 
Published: January 2024

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<p>When customers complain, they express their dissatisfaction with a company or a service provider and request that their complaints are processed. Accordingly, this paper tries to determine the role of perceived responsibility in managing complaints following a service dysfunction. After a review of the relevant literature, we propose a research model that estimates how perceived responsibility mediates the contribution of justice dimensions to customer satisfaction and this latter’s effect on the relationship between perceived quality and perceived justice dimensions. The proposed model is tested on a sample of 350 patients from several private clinics located in Tunis. </p>
Energy is an entity that makes transformation possible
Authors: Alvarado Reyes José Manuel 
Published: January 2024

Energía. ¿Qué misterios esconde? tanto para los comprometidos como para los desinteresados en la ciencia. Los comprometidos, utilizan y calculan la energía con certeza, y los desinteresados sólo saben de su existencia. Sin embargo, ambos entienden y comparten la misma idea: la energía lo es todo, es la vida y el universo mismo. Para los que indiferentes en la ciencia, basta con entender que es muy importante en su vida diaria, para los propios estudiantes de ciencias basta con saber que su existencia es de gran importancia en todo lo que ocupa un volumen en el espacio. En los cursos de ciencia avanzada de hoy, la energía es un dogma para los estudiantes y un enigma para los educadores; sin embargo, es un fenómeno utilizado con gran certeza de su existencia y con pequeñas incertidumbres en su evaluación. Sin embargo hasta el día se sabe que es algo abstracto y es dificil, o imposible de definir, entender o simplemente explicar qué es la energía, pero sabemos que es real, existe y gobierna todo lo que nos rodea. En el presente trabajo se propone un concepto de energía desde el punto de vista filosófico, sustentado más como un ente real y nada imaginario.
Aspects that constitute citizens’ trust in e-government - A review and framework development
Authors: Lai Chimeng , Lobo Marques Alexandre Joao 
Published: January 2024

The extent of citizens' trust in government determines the success or failure of e-government initiatives. Nevertheless, the idiosyncrasies of the concept and the broad spectrum of its approach still present relevant challenges. This work presents a systematic literature review on e-government trust while elaborating and summarizing a conceptual analysis of trust, introducing evaluation methods for government trust, and compiling relevant research on e-government trust and intentional behavior. A total of 26 key factors that constitute trust have been identified and classified into six categories: Government trust, Trust in Internet and technology (TiIT), Trust in e-government (TiEG), Personal Beliefs, Trustworthiness, and Trust of intermediary (ToI). The value added of this work consists of developing a conceptual framework of TiEG to provide a significant reference for future in-depth studies and research on e-government trust.
Kontribusi Media Powerpoint Interaktif dan Model Problem Based Learning terhadap Hasil Belajar IPAS SDN 2 Kalanglundo
Authors: Pristy Nadhia , Sukartono  
Published: January 2024

The learning outcomes of grade IV students have not shown the expected results. This is because learning tends to be teacher-centred. This study aims to determine the learning outcomes of grade IV students of SDN 2 Kalanglundo Grobogan through Interactive Powerpoint media and Problem Based Learning learning models. This type of research is quantitative, with an ex-post facto design. The population of this study was all grade IV students of SDN 2 Kalanglundo, Ngaringan sub-district, totaling 40 students. The sample of this study amounted to 36 students using the Probability Sampling technique. The data collection method is carried out by questionnaire and documentation methods. The result data that have been obtained are analyzed using normality tests, simple linear regression, multiple linear regression, t-test, f-test, coefficient of determination, effective contribution, and relative contribution. The results of the study showed 1) Interactive Powerpoint learning media had a significant effect on learning outcomes, with tcount = 3.598 > ttable = 2.02. 2) The Problem Based Learning learning model has a significant effect on learning outcomes, with the results of the t test, showing that the value if tcalculate = 3.519 > ttable = 2.10. 3) There is a joint influence between Powerpoint learning media Interactive and Problem Based Learning learning model on learning outcomes, with the results of Fcalculate = 10.014 > Ftable = 3.19.
SOSIALISASI PENGENALAN PENDIDIKAN TINGGI KEPADA SISWA-SISWI SMA N 1 KERITANG KABUPATEN INDRAGIRI HILIR, PROVINSI RIAU
Authors: Khairul Ihwan  , Bindas Asniati , Amin Muhammad , Usman  , Sawitri Nina 
Published: January 2024

Pendidikan Tinggi adalah jenjang pendidikan setelah pendidikan menengah yang mencakup program diploma, program sarjana, program magister, program doktor, dan program profesi, serta program spesialis, yang diselenggarakan oleh perguruan tinggi berdasarkan kebudayaan bangsa Indonesia.Tridharma Perguruan Tinggi yang selanjutnya disebut Tridharma adalah kewajiban Perguruan Tinggi untuk menyelenggarakan Pendidikan, penelitian, dan pengabdian kepada masyarakat. Tujuandarikegiataniniadalahuntukmemperkenalkantridarma dan suasanaperkuliahanbagisiswa-siswi SMA Negri 1 Keritang agar dapatmudahberadaptasinantinyadengan Pendidikan Tinggi yang suasananyaberbedadengan Pendidikan tingkat SLTA.Kesimpulan dariKegiatanPengabdianKepada Masyarakat iniadalahSiswa – Siswi SMA Negri 1 Keritang sangat antusiasuntukmelanjutkan Pendidikan tinggidalammengejarcita-citamembangundaerah. Disarankankepada SMA Negri 1 Kerintanguntukmelakukan expo ataupamerah Pendidikan tinggidenganmengundangperguruantinggiternama di Riau, Sumatera Barat, Jambi, dan PulauJawa.
Gefitinib: Combination Therapy and Complex Delivery Systems (Review)
Authors: Nikolaeva L. L. , Sanarova E. V. , Lantsova A. V. 
Published: January 2024

Introduction. The search for new methods of therapy for non-small cell lung cancer (NSCLC) is an urgent task of modern science. Gefitinib is a targeted drug widely used in the treatment of NSCLC in patients with a mutation in the epidermal growth factor receptor tyrosine kinase domain. However, using of gefitinib and other drugs from the group of tyrosine kinase inhibitors is to limited by rapidly developing resistance, for this reason finding of a ways overcome drug resistance is actual part of research interests.Text. The review is devoted to the use of gefitinib in modern developments: introduction to various targeted delivery systems (liposomes, micelles, microspheres, etc.), studying it in combination with other chemotherapeutic agents, as well as in combination with photo- or thermosensitive compounds in various micro- and nanostructured complexes.Conclusion. As a result of the analysis of literature data, it was shown that, despite the fact that gefitinib is a first-generation drug, foreign and Russian researchers consider it quite promising for further use in the treatment of NSCLC. At the same time, developments are being carried out both in the field of expanding combination therapy and in the field of creating complex structures of targeted action, into which, in addition to gefitinib, photosensitizers or other compounds with photo- or thermosensitive effects are introduced.
SOSIALISASI DAGUSIBU DI KURANJI
Authors: Kurniawan Edy , Utami Evi Fatmi , Idawati Sri , Andriani Helmina , Hardani Hardani 
Published: January 2024

Kesehatan adalah hak asasi manusia dan merupakan investasi, juga merupakan karunia Tuhan, oleh karenanya perlu dipelihara dan ditingkatkan kualitasnya. Promosi kesehatan sangat efektif untuk memelihara dan meningkatkan kesehatan tersebut. Faktor perilaku dan lingkungan mempunyai peranan sangat dominan dalam peningkatan kualitas kesehatan. hal-hal tersebut merupakan bidang garapan promosi kesehatan. Masalah perilaku menyangkut kebiasaan, budaya, dan masalah-masalah lain yang tidak mudah diatasi. Berbagai masalah kesehatan, khususnya terkait obat masih ditemui di masyarakat. Berbagai permasalahan terkait obat dapat dikarenakan masyarakat kurang paham tentang penggunaan dan penanganan obat dengan benar, sehingga perlu dilakukan sosialisasi dagusibu di desa kuranji. Tujuan dari kegiatan ini adalah untuk meningkatkan pengetahuan masyarakat tentang dagusibu sehingga tercapai pengobatan rasional. Kegiatan dilakukan dengan metode sosialisasi dagusibu yang disertai dengan tanya jawab dan pemeriksaan Kesehatan secara gratis pada lanjut usia, ibu dan anak. Kegiatan ini mendapatkan antusiasme yang cukup baik.
SOSIALISASI FAKTOR YANG MEMPENGARUHI KERUSAKAN REKAM MEDIS DI LOKET PENDAFTARAN PUSKESMAS MADAPANGGA BIMA, NTB
Authors: Susilawati Wulandari Dewi , Syamsuriansyah Syamsuriansyah , Putra Rizal Pratama Adi 
Published: January 2024

Rekam medis berkas berisi catatan dan dokumen tentang pasien yang berisi identitas, pemeriksaan, pengobatan, tindakan medis lain pada sarana pelayanan kesehatan untuk rawat jalan, rawat inap baik dikelola pemerintah maupun swasta sehingga harus dijaga keamanan dan kerahasiaannya dari bahaya kerusakan. Observasi awal penulis di bagian penyimpanan Rawat Inap Puskesmas Madapangga Bima NTB dari 50 berkas terdapat 30 (60%) berkas yang telah rusak, sedangkan yang tidak rusak 20 (40%). Kegiatan pengabdian ini bertujuan untuk mengetahui faktor kerusakan berkas rekam medis. Metode yang digunakan dalam pengabdian ini dengan ceramah, diskusi dan tanya jawab. Hasil menunjukkan setelah dilakukan pengabdian bahwa ada beberapa faktor yang mempengaruhi kerusakan rekam medis dilihat dari faktor intrinsik dan ekstrinsinya, dimana faktor dari instrinsik berkas rekam medis dibuat dalam bentuk buku, kemudian tidak semua berkas dibuat dalam bentuk buku, tetapi dibuat dalam kertas dan karton berwarna kuning tanpa menggunakan map. Dengan adanya kegiatan ini dapat meningkatkan pengetahuan petugas di puskesmas rawat inap.
SOSIALISASI SOSIALISASI KEY PERFORMANCE INDIKATOR (KPI) BAGI INDUSTRI DALAM MENGUKUR EFEKTIVITAS HASIL PRODUKSI
Authors: Aini Aini , Maulana Alfi 
Published: January 2024

Key performance Indicators (KPI) adalah metode ukur untuk mengukur kinerja tertentu yang banyak diterapkan pada dunia industri diantaranya untuk mengukur efektifitas terhadap hasil produksi, efisiensi bahan bakar atau efisiensi air atau bahan material. Penggunaan key performance Indicator (KPI) merupakan alat untuk mengevaluasi dan memberikan penilaian strategis terhadap tujuan yang telah ditetapkan. Tujuan pengabdian ini adalah untuk untuk memberikan sosialisasi tentang key performance indikator kepada pelaku industri. Manfaat pemberian keterampilan tentang indikator adalah agar dapat mengukur kinerja, sistem pengukuran kinerja, fokus pada orientasi tujuan organisasi peningkatan budaya kinerja dan akuntabilitas. Sosialisasi diberikan kepada jaringan manajemen tingkat menengah dan atas. Target pemilihan sasaran penerima sosialisasi adalah merupakan bagian yang bertugas untuk mengukur kinerja organisasi. Sosialisasi diberikan selama dua hari. Evaluasi masing-masing bagian dilakukan dengan cara kemampuan untuk membuat target pada masing-masing bagian dalam bentuk angka kuantitatif dan dimasukkan ke dalam matrik pengukuran key performance indikator ( KPI). Sebagai indikator keberhasilan masing-masing bagian dibuat standar nilai yang merujuk pada nilai A hingga nilai D. Hasil akhir pengabdian diperoleh bahwa seluruh bagian dapat membuat target dan indikator untuk evaluasi masing-masing departemen. Evaluasi dalam kegiatan ini dilakukan pada bulan berikutnya dengan melihat keberlangsungan penggunaan untuk pengukuran efektivitas.
Ex vivo normothermic preservation of a kidney graft from uncontrolled donation after circulatory death over 73 hours
Authors: Montagud-Marrahi Enrique , Luque Yosu , Ros Ruben Rabadan , Ajami Tarek , Cuadrado-Payan Elena , Estrella Hector , Arancibia Andres , Sánchez-Etayo Gerard , Bohils Marc , Marrero Ramsés , Fundora Yilliam , Ramírez-Bajo Maria José , Banon-Maneus Elisenda , Rovira Jordi , Larque Ana-Belén , Campistol Josep Maria , Diekmann Fritz , Musquera Mireia 
Published: January 2024

The transplant community is focused on prolonging the ex vivo preservation time of kidney grafts to allow for long-distance kidney graft transportation, assess the viability of marginal grafts, and optimize a platform for the translation of innovative therapeutics to clinical practice, especially those focused on cell and vector delivery to organ conditioning and reprogramming. We describe the first case of feasible preservation of a kidney from a donor after uncontrolled circulatory death over a 73-h period using normothermic perfusion and analyze hemodynamic, biochemical, histological, and transcriptomic parameters for inflammation and kidney injury. The mean pressure and flow values were 71.24 ± 9.62 mmHg and 99.65 ± 18.54 mL/min, respectively. The temperature range was 36.7°C–37.2°C. The renal resistance index was 0.75 ± 0.15 mmHg/mL/min. The mean pH was 7.29 ± 0.15. The lactate concentration peak increased until 213 mg/dL at 6 h, reaching normal values after 34 h of perfusion (8.92 mg/dL). The total urine output at the end of perfusion was 1.185 mL. Histological analysis revealed no significant increase in acute tubular necrosis (ATN) severity as perfusion progressed. The expression of KIM-1, VEGF, and TGFβ decreased after 6–18 h of perfusion until 60 h in which the expression of these genes increased again together with the expression of β-catenin, Ki67, and TIMP1. We show that normothermic perfusion can maintain a kidney graft viable ex vivo for 3 days, thus allowing a rapid translation of pre-clinical therapeutics to clinical practice.
Local knowledge matters: understanding the decision-making processes of communities under climate change in Suriname
Authors: Smith Gwendolyn , Chowenga Mawie , Karsters Jethro 
Published: January 2024

IntroductionTraditionally, local communities have relied on practical observations accumulated over extended periods to inform their decision-making. This knowledge is now recognized as a viable solution for communities to adapt to climate change effectively. The impact of climate change brings an extra layer of complexity to local communities' detection- and decision-making processes, which needs to be better comprehended.MethodologyOur study builds on the foundation of conflict resolution and examines the knowledge systems and corresponding decision-making processes of local communities living in urban, rural, and tropical forest regions of Suriname, South America.ResultsThe mixed-method study showed that the autonomous decision-making processes of these communities are guided by their knowledge systems, intertwined with values and interests. Forest communities in remote locations rely solely on their robust knowledge base for crafting adaptation solutions, while urban and rural communities near the administrative centers develop adaptation strategies primarily considering their access to social networks and relative power.DiscussionThe study highlights local knowledge as the primary determinant for the direction communities take in adaptation, with tradeoffs becoming evident as communities navigate the broader social context. The recognition and integration of this knowledge emerge as a critical factor in enhancing climate change adaptation at the local level.
Process analysis of the patient pathway for automated data collection: an exemplar using pituitary surgery
Authors: Hanrahan John G. , Carter Alexander W. , Khan Danyal Z. , Funnell Jonathan P. , Williams Simon C. , Dorward Neil L. , Baldeweg Stephanie E. , Marcus Hani J. 
Published: January 2024

IntroductionAutomation of routine clinical data shows promise in relieving health systems of the burden associated with manual data collection. Identifying consistent points of documentation in the electronic health record (EHR) provides salient targets to improve data entry quality. Using our pituitary surgery service as an exemplar, we aimed to demonstrate how process mapping can be used to identify reliable areas of documentation in the patient pathway to target structured data entry interventions.Materials and methodsThis mixed methods study was conducted in the largest pituitary centre in the UK. Purposive snowball sampling identified frontline stakeholders for process mapping to produce a patient pathway. The final patient pathway was subsequently validated against a real-world dataset of 50 patients who underwent surgery for pituitary adenoma. Events were categorized by frequency and mapped to the patient pathway to determine critical data points.ResultsEighteen stakeholders encompassing all members of the multidisciplinary team (MDT) were consulted for process mapping. The commonest events recorded were neurosurgical ward round entries (N = 212, 14.7%), pituitary clinical nurse specialist (CNS) ward round entries (N = 88, 6.12%) and pituitary MDT treatment decisions (N = 88, 6.12%) representing critical data points. Operation notes and neurosurgical ward round entries were present for every patient. 43/44 (97.7%) had a pre-operative pituitary MDT entry, pre-operative clinic letter, a post-operative clinic letter, an admission clerking entry, a discharge summary, and a post-operative histopathology pituitary multidisciplinary (MDT) team entries.ConclusionThis is the first study to produce a validated patient pathway of patients undergoing pituitary surgery, serving as a comparison to optimise this patient pathway. We have identified salient targets for structured data entry interventions, including mandatory datapoints seen in every admission and have also identified areas to improve documentation adherence, both of which support movement towards automation.