bluuebunny/crossref_metadata_2025_split huggingface dataset:
Postoperative symptom changes following uterine artery embolization for uterine fibroid based on FIGO classification
Authors: Nozaki Yoshimi , Takeuchi Shiori , Arai Masafumi , Kuwatsuru Yoshiki , Toei Hiroshi , Okada Shingo , Kato Hitomi , Saito Naoko , Nobushima Takamichi , Murakami Keisuke , Kitade Mari , Kuwatsuru Ryohei 
Published: January 2025

Abstract

Background
Classifying uterine fibroid using the International Federation of Gynecology and Obstetrics (FIGO) classification system assists treatment decision-making and planning. This study aimed to study whether different fibroid locations influence clinical outcomes following uterine artery embolization (UAE).

Methods
This is a retrospective cohort study of patients who underwent UAE for symptomatic uterine fibroid between December 2016 and January 2023 at our hospital. Changes in mean fibroid volume were compared based on MR images. Menstrual pain, excessive flow symptoms, and treatment satisfaction before UAE and 6 months after UAE were compared.

Results
A total of 149 premenopausal patients (mean age 45.7 ± 2.7 years) were included for analysis (FIGO 2/3, n = 57; FIGO 4–7, n = 92). Baseline menstrual pain, fibroid, and uterine volume before UAE were comparable between the two FIGO groups (p > 0.05). The menstrual flow index was higher for the FIGO 2/3 group (mean ± SD [min–max]: 9.4 ± 1.4 [4–10] vs 8.0 ± 2.3 [0–10], p < 0.001). Six months after UAE, the improvements in menstrual flow index (mean ± SD]: -3.7 ± 2.6 vs -2.6 ± 2.2, p = 0.035), fibroid volume (mean ± SD: -54.7 ± 21.7% vs -39.8 ± 16.2%, p < 0.001), and uterine volume (mean ± SD: -38.2 ± 16.3% vs -31.1 ± 11.6%, p = 0.008) in the FIGO 2/3 group were significantly higher than the FIGO 4–7 group. Both groups had comparable improvements in menstrual pain index (-2.1 ± 2.6 vs -1.8 ± 2.5, p = 0.008) and 88% of the patients were satisfied or very satisfied overall.

Conclusion
UAE treatment satisfaction was high for patients with fibroids at different FIGO stages. UAE treatment outcomes were better for patients with fibroids affecting the endometrium (FIGO 2/3).

Level of evidence
3B, Retrospective observational study.
Physical activity, fatigue severity, and health-related quality of life of community-dwelling stroke survivors: a cross-sectional study
Authors: Odetunde Marufat Oluyemisi , Makinde Ayomide Felix , Jimoh Olamide Mary , Mbada Chidozie Emmanuel , Niyi-Odumosu Faatihah , Fatoye Francis 
Published: January 2025

Abstract

Background
Physical inactivity among stroke survivors (SSV) may result from fatigue, physical disabilities, and psychosocial factors, all of which adversely affect health-related quality of life (HRQL). Studies on combined interactions among physical activity (PA), fatigue severity (FS), and HRQL in SSV are scarce. This study was aimed to determine the relationships among PA, FS, and HRQL in community-dwelling SSV and to predict the association with selected socio-demographic and clinical variables.

Methods
This analytical cross-sectional correlation study involved 102 consented community-dwelling SSV. Respondents were purposively recruited from physiotherapy outpatient clinics of selected secondary and tertiary hospitals in southwest Nigeria. PA, FS, and HRQL of the SSV were assessed using the Stroke Physical Activities Questionnaire (SPAQ), Fatigue Severity Scale (FSS), and Stroke-Specific Quality-of-Life (SS-QoL) scale, respectively. Information on respondents’ socio-demographic and clinical characteristics was also collected. Data were analyzed using descriptive and inferential statistics at p < 0.05 significance level.

Results
Respondents’ mean age was 59.98 ± 11.59 years. The majority were females (52.9%), had ischemic stroke (72%), and with right-side weakness (54%) of over 6 months (80%). Respondents’ mean scores on SPAQ, FSS, and SS-QoL scales are 1867.47 ± 1817.93 MET min/week, 31.94 ± 11.29, and 156.47 ± 26.62, respectively. There were no significant associations between selected socio-demographic/clinical variables and physical activity levels except in gender (χ
2 = 6.737; p = 0.034), fatigue severity except in side of affectation (χ
2 = 5.839; p = 0.054), and HRQL except in level of education (χ
2 = 23.497; p = 0.001) and side of affectation (χ
2 = 7.389; p = 0.007). There was a moderate and significant correlation (R = 0.426; p < 0.05) among PA, FS, and HRQL. Regression analysis revealed no significant associations with the socio-demographic/clinical variable except the side of affectation for HRQL, low (R = 0.223) level of prediction of socio-demographic/clinical variables for PA (F 8, 93 = 0.607; p > 0.05), and fair (R = 0.326) level of prediction for FS (F 8, 93 = 1.386; p > 0.05).

Conclusion
Moderate correlations among fatigue severity, physical activity, and health-related quality of life in stroke survivors suggested that enhancing one domain can benefit others, while the limited predictive ability of socio-demographic and clinical variables highlighted the need to consider cultural and psychological factors in post-stroke outcomes.
Clearing the path for whole-mount labeling and quantification of neuron and vessel density in adipose tissue
Authors: Rauchenwald Thomas , Benedikt-Kühnast Pia , Eder Sandra , Grabner Gernot F. , Forstreiter Sebastian , Lang Michaela , Sango Roko , Eisenberg Tobias , Rattei Thomas , Haschemi Arvand , Wolinski Heimo , Schweiger Martina 
Published: January 2025

ABSTRACT
White adipose tissue (WAT) comprises a plethora of cell types beyond adipocytes forming a regulatory network that ensures systemic energy homeostasis. Intertissue communication is facilitated by metabolites and signaling molecules that are spread by vasculature and nerves. Previous works have indicated that WAT responds to environmental cues by adapting the abundance of these ‘communication routes’; however, the high intra-tissue heterogeneity questions the informative value of bulk or single-cell analyses and underscores the necessity of whole-mount imaging. The applicability of whole-mount WAT-imaging is currently limited by two factors – (1) methanol-based tissue clearing protocols restrict the usable antibody portfolio to methanol-resistant antibodies and (2) the vast amounts of data resulting from 3D imaging of whole-tissue samples require high computational expertise and advanced equipment. Here, we present a protocol for whole-mount WAT clearing, overcoming the constraints of antibody-methanol sensitivity. Additionally, we introduce TiNeQuant (for ‘tissue network quantifier’) a Fiji tool for automated 3D quantification of neuron or vascular network density, which we have made freely available. Given TiNeQuants versatility beyond WAT, it simplifies future efforts studying neuronal or vascular alterations in numerous pathologies.
The necessity of ulnar nerve exploration and translocation in open reduction of medial humeral epicondyle fractures in children
Authors: Liu Shaoshan , Su Yuxi 
Published: January 2025

AimsMedial humeral epicondyle fractures (MHEFs) are common elbow fractures in children. Open reduction should be performed in patients with MHEF who have entrapped intra-articular fragments as well as displacement. However, following open reduction, transposition of the ulnar nerve is disputed. The aim of this study is to evaluate the need for ulnar nerve exploration and transposition.MethodsThis was a retrospective cohort study. The clinical data of patients who underwent surgical treatment of MHEF in our hospital from January 2015 to January 2022 were collected. The patients were allocated to either transposition or non-transposition groups. Data for sex, age, cause of fracture, duration of follow-up, Papavasiliou and Crawford classification, injury-to-surgery time, preoperative ulnar nerve symptoms, intraoperative exploration of ulnar nerve injury, surgical incision length, intraoperative blood loss, postoperative ulnar nerve symptoms, complications, persistent ulnar neuropathy, and elbow joint function were analyzed. Binary logistic regression analysis was used for statistical analysis.ResultsA total of 124 patients were followed up, 50 in the ulnar nerve transposition group and 74 in the non-transposition group. There were significant differences in ulnar nerve injury (p = 0.009), incision length (p < 0.001), and blood loss (p = 0.003) between the two groups. Binary logistic regression analysis revealed that preoperative ulnar nerve symptoms (p = 0.012) were risk factors for postoperative ulnar nerve symptoms. In addition, ulnar nerve transposition did not affect the occurrence of postoperative ulnar nerve symptoms (p = 0.468).ConclusionUlnar nerve transposition did not improve clinical outcomes. It is recommended that the ulnar nerve should not be transposed when treating MHEF operatively.Cite this article: Bone Joint J 2024;106-B(2):212–218.
Long-term Prognosis of Nonceliac Enteropathies and a Score to Identify Patients With Poor Outcomes: A 30-year Multicenter Longitudinal Study
Authors: Schiepatti Annalisa , Maimaris Stiliano , Scalvini Davide , Raju Suneil A. , Ingham Katerina E. , Johnson Calvin M. , Rubio-Tapia Alberto , Maruggi Chiara , Malamut Georgia , Lenti Marco Vincenzo , Di Sabatino Antonio , Caio Giacomo , Volta Umberto , Zingone Fabiana , Marasco Giovanni , Barbara Giovanni , Makharia Govind , Mehra Lalita , Das Prasenjit , Lundin Knut E.A. , Cross Simon S. , Sanders David S. , Biagi Federico 
Published: January 2025

INTRODUCTION:
Long-term prognosis of nonceliac enteropathies (NCEs) is poorly understood. We aimed to evaluate long-term outcomes and develop a prognostic score for NCEs.

METHODS:
NCEs patients from an international multicenter cohort (4 Italian centers, 1 United Kingdom, 1 French, 1 Norwegian, 1 United States, 1 Indian) followed-up over 30 years were enrolled. Complications and mortality were analyzed with Kaplan-Meier curves, standardized mortality ratios (SMR), and multivariate Cox regression. A clinical score to identify patients at risk of poor outcomes was developed.

RESULTS:
Two hundred sixty-one patients were enrolled (144 female, mean age at diagnosis 49 ± 18 years, median follow-up 70 months, interquartile range 24–109). The most common etiologies were idiopathic villous atrophy (39%), drug related (17%), common variable immune deficiency (15%), infectious (10%), and autoimmune enteropathy (9%). Five-year and 10-year complication-free survival were 89% and 77%, respectively, whereas 5-year and 10-year overall survival were 88% and 74%, respectively. Causes of death included sepsis/major infections (22%), lymphoproliferative disorders (22%), solid-organ malignancies (12%), cardiovascular/metabolic disease (10%), and was unknown in 33%. Mortality was increased in NCEs compared with the general population (SMR 3.17, 95% confidence interval [CI] 2.24–4.34). Older age at diagnosis (P < 0.001), anemia (hazard ratio [HR] 2.53, 95% CI 1.33–4.80, P < 0.01), and lack of clinical (HR 3.21, 95% CI 1.68–6.18, P < 0.01) and histological response (HR 2.14, 95% CI 1.08–4.23, P = 0.04) were independent predictors of mortality at Cox regression. A 5-point score was developed to identify high-risk patients: very low risk (0 pts), low risk (1–2 pts), intermediate risk (3 pts), and high risk (4–5 pts), with 10-year survival rates of 100%, 87%, 62%, and 16%, respectively.

DISCUSSION:
Mortality in NCEs is increased because of complications and lack of response to current therapies. We developed a clinical score to personalize follow-up. Targeted treatments are needed to improve outcomes.
Fact or Myth? Black Patients Do Not Want to Participate in Clinical Trials
Authors: Mills Krystal , Figueroa Francisco , Knight RaKetra , Ekpo Emem , Lee Lilian C. , Baldo Lance , Xu Chuanbo , Wang Siqi , Adelman Robert M. , Pemu Priscilla , Levin Theodore , Shaukat Aasma , Liu Julia J. 
Published: January 2025

Objectives:
To assess strategies for optimizing participation of underserved minorities in a blood-based early CRC detection test study (PREEMPT CRC; NCT04369053) at a hospital serving primarily Black patients.

Methods:
Culturally sensitive, racially congruent research staff approached patients undergoing average-risk screening colonoscopy. Consent/study procedures were synchronized with clinical appointments. Enrolled and not-enrolled patient characteristics were compared. Recruitment was compared with other study sites.

Results:
247/509 eligible participants enrolled; most identified as Black (88.7%). No baseline characteristics were associated with participation. Recruitment was high compared to other sites (11th centile).

Conclusions:
Recruitment barriers for Black individuals can be overcome when easy, culturally sensitive access is facilitated.
ANALISIS KINERJA KEUANGAN BANK MUAMALAT INDONESIA (BMI)	TAHUN 1994-1998 DAN TAHUN 1999-2003
Authors: Muharam Harjum , Handayani Suyati 
Published: January 2025

Using paired sample t-test this research analyze financial performance of Bank Muamalat Indonesia between 1994-1998 and 1999-2003. Profitability ratios, liquidity tsuos, solvability ratios, and commitment to economy and Moslem community ratio are used as financial performance. The results show there are no significance different financial performance during 1994-1998 and 1999-2003 period except commitment to economy and Moslem community ratio.
INCORPORATING OPERATIONAL EXCELLENCE STRATEGY INTO COMPANY FINANCIAL PERFORMANCE IN OIL AND GAS INDUSTRY: AN EMPIRICAL STUDY
Authors: Ciptono Wakhid Selamet 
Published: January 2025

The objective of this research is to test the effect of Quality Management Practices (QMP) based on Deming's 14 points, Operational Excellence Strategy (OE), on company financial pettotmsnce (CFP). Conceptual model of Deming's Principle is used with operational excellence strategy (operational excellence dimensions and investment level) as mediating variables between the independent variables of Quality Management Practices and the dependent variable of company financial pertormance. The survey instrument usede comprehensive set of 81 importance and performance questions that were directly tied to the eight constructs of the study.In summary, eight causal paths specified in the hypothesized model were found to be positive and statistically significant. Furthermore empirical results suggest that quality management practices have a positive and significant indirect effect on company financial performance through its direct effect on operational excellence strategy. The results also show that a complete model ftt and the acceptable parameter level which indicate the overall parameter are good fit between the hypothesized model and the observed data. By concentrating on a single industry (oil and gas) is that Structural Equation Modeling (SEM) specification of the sequentialrelationship model between eight research constructs can be more complete and specific because unique characteristics of the oil and gas industry can be included (e.g. upstream and downstream chain activities). Finally, the particular design of the research and the findings suggest that the final structural model of the study has a great potential for replication to manufacturing as well as service operations.Based on the oil and gas managers (the SBU level), operational excellence strategy (five meaningful factors of operational excellence) can be viewed as the effective use of production and operations capability and technology for achieving business and corporate goals. Operational excellence strategy, therefore, is to help a company's operations organization define the common ground where it can play a proactive and collaborative role with other company functions or cross-functional relationships.Oil and gas managers in Indonesia can use these meaningful factors of operational excellence in concert with other critical quality management practices to help them in their word-class company initiatives. Researchers can also use these factors to build structural model linking such factors to various organizational performance measures (i.e., non-financial or value- gain and financial or monetary-gain performances).
Strategi Mitigasi Risiko Pengelolaan Mangrove pada Kelompok Usaha Karya Makmur Jaya
Authors: Hindrayani Lilik , Arifiyanti Nurul , Sugiarti Teti 
Published: January 2025

Luasan hutan mangrove di Indonesia mengalami degradasi yang disebabkan oleh berbagai kerusakan sehingga rehabilitasi menjadi salah satu upaya penanganan pemulihan ekosistem. Proses pengelolaan mangrove tidak terlepas dari adanya risiko internal operasional maupun eksternal yang dapat menyebabkan kegagalan tanam. Karya Makmur merupakan kelompok usaha yang peduli terhadap keberlanjutan hutan mangrove dan focus pada penyediaan pasokan bibit di daerah pantai utara Kabupaten Bangkalan Madura. Pada area pengelolaan Kelompok Usaha Karya Makmur menunjukkan adanya risiko kegagalan seperti tidak berkembangnya bibit dengan sempurna sehingga berdampak pada kerugian produksi dan finansial. Penelitian ini bertujuan untuk mengidentifikasi dan merumuskan strategi mitigasi risiko pengelolaan mangrove pada kelompok usaha Karya Makmur. Cakupan penelitian berfokus pada usaha pembibitan mangrove dengan menggunakan metode analisis House of Risk (HOR). Teridentifikasi alur proses bisnis pada pembibitan mangrove diawali dengan persiapan lahan, persiapan media tanam, persiapan benih, penanaman benih, dan perawatan bibit. Hasil menunjukkan terdapat risk event dan risk agent pada kelompok usaha Karya Makmur Jaya dengan urutan prioritas yakni benih yang bagus sulit didapat, adanya penyakit, terdapat hama pengganggu, kelalaian dalam penyiraman, kurangnya modal, dan perubahan cuaca dan iklim tidak menentu. Strategi mitigasi risiko yang dapat diterapkan utamanya yakni penyortiran benih mangrove dan diikuti dengan pengawasan pekerjaan karyawan, pemberian pestisida, bekerjasama dengan masyarakat dalam pengendalian kepiting, pelatihan tenaga kerja, dan pemberian teduhan.
Compressive properties and energy absorption of ordered porous aluminum with strengthening structures
Authors: Li Moqiu , Bai Yu , Su Mingming , Hao Hai 
Published: January 2025

Abstract
In this paper, Z-strengthening structure (strengthening the Z-axis struts) and Graded-Z-strengthening structure (strengthening the Z-axis struts and node by gradient) based on cubic structure were investigated. Specimens were fabricated by indirect additive manufacturing. The compressive properties and energy absorption were characterized by axial quasi-static compression tests. The results showed that Z-strengthening enhances the compressive properties and energy absorption capacity of the original cubic structure. As for Graded-Z-strengthening, the stiffness of the structures was further increased. Moreover, different strengthening structures change the failure mode of the structures, which has a significant effect on mechanical properties and energy absorption capacities.
A quantitative method for syntactic gradience: words, phrases, and the constructions in between
Authors: Wu Zhen 
Published: January 2025

Abstract
Syntactic gradience has been studied mainly from a qualitative perspective. In this paper, I propose a new method, based on the process of multi-criteria decision-making, that can quantify the word-phrase gradience against the standardized morphosyntactic continuum. This method may be applied to both synchronic and diachronic research, with the discrepancies between compounds and idioms and the lexicalization of compound pronouns in English examined as illustrations.
Testing the effect of speech separation on vowel formant estimates
Authors: Stanley Joseph A. , Johnson Lisa Morgan , Brown Earl Kjar 
Published: January 2025

Abstract
While recent advances in sociophonetic data processing have made it possible to analyze large datasets and audio not originally intended for linguistic analysis, overlapping speech in recordings with multiple speakers continues to be an issue that results in lost data. We evaluate whether current source separation models produce audio that is clean enough to produce reliable measurements for sociophonetic analysis. We compare formant estimates from a pair of pristine recordings and merged-and-separated versions of those same recordings using the Libri2mix, Whamr16K, and WSJ02mix source separation models. Based on auditory inspection of the separated files, visualization of vowel formant estimates, and statistical analysis, Libri2 performed best and WSJ02 was worst. While the mean formant measurements per vowel were usually small, differences for each observation were larger in unpredictable ways. We are cautiously optimistic about using these tools in sociophonetic analysis, so long as analysis is conducted on vowel means. We conclude with recommendations that researchers can implement when using source separation in sociophonetic research.
The regularity of solutions to the L

p
Gauss image problem
Authors: Jia Xiumei , Chen Jing 
Published: January 2025

Abstract
The

L

p

{L}_{p}

Gauss image problem amounts to solving a class of Monge-Ampère type equations on the sphere. In this article, we discuss the regularity of solutions to the

L

p

{L}_{p}

Gauss image problem.
From principles to practice: a comprehensive guide to FRET-FLIM in plants
Authors: Eljebbawi Ali , Dolata Anika , Strotmann Vivien I. , Weidtkamp-Peters Stefanie , Stahl Yvonne 
Published: January 2025

Abstract
Förster Resonance Energy Transfer combined with Fluorescence Lifetime Imaging Microscopy (FRET-FLIM) is revolutionizing plant biology, by enabling the study of protein–protein interactions (PPIs) within live cells. This manuscript describes the principles of FRET and the practical application of FRET acceptor photobleaching (FRET-APB) in exploring PPIs in vivo. It mainly focuses on the superior characteristics of FRET-FLIM and details the materials and methods for implementing this technique in plants. It provides a profound overview about the required instruments, protocols for sample preparation, methods for calibration and acquisition, and pipelines for data analyses including novel analyses for binding and FRET efficiencies. Furthermore, it discusses the potential pitfalls and challenges related to the sample autofluorescence, protein expression heterogeneity, and acquisition photodamage or bleaching. This works aims to highlight the great prospects of FRET-FLIM in advancing our understanding of PPIs in living plant cells.