bluuebunny/crossref_metadata_2025_split huggingface dataset:
Research of nonparametric density estimation algorithms by applying clustering methods
Authors: Šmidtaitė Rasa , Ruzgas Tomas 
Published: October 2023

One of the ways to improve the accuracy of probability density estimation is multi-mode density treating as the mixture of single-mode one. In this paper we offer to use data clustering in the first place and to estimate density in every cluster separately. To objectively compare the performance, Monte Carlo approximation is used. While using various methods to evaluate the accuracy of probability density estimations we tried to use clustered and not clustered data. In this paper we also tried to reveal the usefulness of using clustering for data generated by single-mode and multi-mode distributions.
The Differences in Understanding Hominized Being in the Art Philosophy of Šliogeris and Heidegger
Authors: Kavaliauskas Tomas 
Published: October 2023

Two different philosophical attitudes towards the hominized Being are analyzed: the one of Arvydas Šliogeris and the other of Martin Heidegger. The aim is to show the philosophy of Being in relation to particular paintings. Šliogeris interprets the picture of The Great Pine Tree by Paul Cézanne, whereas Heidegger – the picture of A Pair of Shoes by Vincent van Gogh. The author of the article explains how Aristotle’s concept of the individual substance is related to the art philosophy of Šliogeris. The article also shows how Šliogeris’ critique of the hominized Being consistently evolved starting with his book The Thing and Art and culminating with his major work, titled The Silence of Transcendence. At the end of the article the author brings to the reader’s attention two self-contradictory notions of an artist that we find in different books of Šliogeris: the first notion that speaks of a Human-artist who supposedly imbues ‘more Being’ into a painting than we find it in nature; whereas the second notion speaks of a Nature-artist and provides to things ‘more Being’ than we find it in art.
The Problem of Image’s Status: E. Alloa’s Symptomatology
Authors: Vachninas Benediktas 
Published: October 2023

This article analyzes one of the most recent theories of visual thinking – Emmanuel Alloa’s symptomatology of images. The article focuses on the problem of the status of image, which is considered in various ways by authors of the pictorial and iconic turns. The article raises the question “What is the status of image in respect of language?” The article goes back to the origins of symptomatology of images, in particular, to Nelson Goodman’s theory of symbols. This allows showing the originality of Alloa’s model of symptoms and rehabilitating the status of symptomatological investigation. It is thus claimed that the iconic status of images in relation to language can be reformulated raising the question of the symptom’s identity. In this respect, the symptoms of iconic are instruments that enable the description of images with regard to different layers of iconicity.
Biopolitics of the Zombie Corpses: Collectivity, Contagion, and Alterity
Authors: Kartal Onur 
Published: October 2023

Inasmuch as the society is considered as a body today, social problems should be defined accordingly, as problems of hygiene and cleanliness. In this regard, various representations of zombie corpses in zombie movies can be conceived as concrete examples of threat and a perception of disease. In this article, I claim that the zombie figures in cinema bear a positive potential for the social life of humanity, and I will define this potential as a new opportunity for meeting the absolute alterity. Within this context, I analyse 28 Weeks Later and The World War Z and The Girl with All the Gifts to put forth the idea that what enables emancipation of humanity is contagion and alterity. Rather than destroying the capitalist rationalization without offering any alternatives, zombie corpses enounce the birth of a new form of social life as analysed through Pride and Prejudice and Zombies.
Klinikai és biológiai prognosztikai tényezők vizsgálata follikuláris lymphomás betegek kezelése során
Authors: Kiss Evelin , Kenyeres Anna , Illés Árpád , Simon Zsófia , Jóna Ádám 
Published: October 2023

BevezetésA follikuláris lymphoma az egyik leggyakoribb B-sejtes lymphoproliferatív kórkép. Kifejezetten heterogén betegségről beszélünk, ebből adódóan a terápiaválasztásban is több lehetőség biztosítására kell törekednünk. Az úgynevezett „személyre szabott” kezelés felé irányuló kutatások kiemelkedően fontosak, ezt célozta meg a Debreceni Egyetem Hematológiai Tanszékén végzett tudományos munkánk is.Betegek és vizsgálati módszerekAz adatokat retrospektíven, 2009 májusától 2020 júniusáig kezelt 143 betegünktől gyűjtöttük össze, valamint 2004 és 2021 között összegyűjtöttük az autológ őssejt-transzplantáción átesett betegek adatait is, összesen 49 esetben. Összefoglalónkban a jelenleg ismert és a lehetséges új prognosztikai tényezőkről, valamint az autológ őssejtterápiában használható prognosztikai faktorok létjogosultságáról számolunk be. Multivariáns analízisek alkalmazásával, ROC-görbe használatával határoztuk meg a progressziómentes túlélést és a teljes túlélést befolyásoló faktorokat.EredményekStaging PET/CT SUVmax 9,85-ös cut-off érték mellett, (P = 0,0001, [HR]: 0,2535, 95%-os [CI]: 0,1118–0,4878) és a Ly/Mo arány 3,41-es cut-off érték mellett (P = 0,0027, HR: 2,997, 95% CI: 1,463–6,142) szignifikánsan befolyásolta a betegek progressziómentes túlélését. A staging SUVmax >9,85 és Ly/Mo < 3,41 cut-off értékek együttesen egy nagy rizikójú csoportot azonosítanak. (P < 0,0001, HR: 0,0957, 95% CI: 0,03416–0,2685). Hasonlóan szignifikáns különbséget mutattunk ki a 3,15-ös SUVmax köszöbértékkel az interim PET/CT-nél (P < 0,0001, HR: 0,1614, 95% CI: 0,06684–0,3897). A 9,85 feletti staging SUVmax és az interim SUVmax >3,15 együttvéve rossz prognózist jelent (P < 0,0001, HR: 0,1037, 95% CI: 0,03811–0,2824). A PFS-különbség az utóbbi esetben OS-beli különbségben is megmutatkozik (P = 0,0506, HR: 0,1187, 95% CI: 0,01401–1,005). Az ASCT-n átesett 49 beteg esetén, PFS tekintetében a 47 év feletti életkor és a Ly/Mo arány 2,675-ös cut-off feletti értékek együttesen egy rossz prognózisú csoportot definiálnak (P = 0,0019). OS vonatkozásában viszont csak az életkor bizonyult szignifikánsnak.KövetkeztetésA Ly/Mo arány, mint biológiai prognosztikai tényező javíthatja a PET/CT prognosztikai erejét. A PFS-ben megfigyelt túlélési előny az OS-ben is megjelenik, amennyiben a staging és az interim SUVmax értékek kombinációját használjuk. ASCT esetén az életkor mellett a Ly/Mo arány bizonyult prognosztikusnak a PFS tekintetében.
Confirmation of the Legality of Applying a Zero VAT Rate and Exemption from Excises when Exporting Goods to the EAEU Member States
Authors: Lagkueva I. V. 
Published: October 2023

The article analyzes the changes in the procedure for confirming the zero VAT rate in the procedure for customs export on the territory of the Eurasian Economic Union. The author considers the provisions introduced by the Federal Law (№ 173-FZ) The article highlights the most significant innovations of the simplifying amendments to the process of confirming the zero VAT rate for carriers of exported goods: the obligation to stamp customs authorities on a number of transport documents is cancelled. The issues of ensuring the unification of standards and certification of products, improving measures for the protection of intellectual property rights, taking into account the increase in the digital exchange of information between the countries — participants of the EAEU, are considered.
ESTABILIDADE E ADAPTABILIDADE DE PROGÊNIES DE AÇAÍ DA ETNOVARIEDADE BRANCA NO PARÁ
Authors: Yokomizo Gilberto Ken Iti , Hongyu Kuang , Matos Ana Késsia Freitas de , Oliveira Maria do Socorro Padilha de , Santos Eneas Correa dos 
Published: October 2023

The growing demand for the black or violet açaí pulp has ​​generated the elimination of other varieties in the production area, such as the white ethnovariety. The anthropic pressure in search only of the black ethnovariety has generated genetic erosion of the white açaí, therefore, studies showing its importance and existence are important. The objective of this work was to verify the diversity in white açaí progenies of the active germplasm bank of Embrapa Amazônia Oriental. The experiment contains 52 progenies installed in 2003, in a completely randomized design, with ten replications of one plant per plot, spaced 5 m x 5 m. The characteristics evaluated were total bunch weight (PTC) in kg; fruit weight in bunches (PFC) in kg; fruit yield per bunch (RFC), in % and; weight of one hundred fruits (PCF) in g, and the AMMI graphical analyzes were used in the obtained data. The results show that the progenies with the greatest contribution to the averages and with the greatest stability are G27 and G18 for PTC and PFC; G27, G16, G18 and G12 for RFC and G1, G27 and G50 for PCF. Highlighting the G27 progeny in all characteristics. It was concluded that progenies with stability and adaptability are important for genetic improvement; BAG progenies present variability for selection; there is the possibility of recommending material selected for cultivation, generating greater dissemination of the white ethnovariety açaí tree for consumption, reducing the possibilities of its extinction
Explorative Analysis of Lazismu Pusat YouTube Channel
Authors: Furqonul Haq  
Published: October 2023

YouTube adalah salah satu media informasi yang digemari banyak orang saat ini. Informasi terkait kinerja lembaga-lembaga zakat di Indonesia dapat diperoleh dari channel YouTubenya, misalnya channel YouTube Lazismu Pusat. Tujuan penelitian untuk menganalisis secara kualitatif profil dan kolom-kolom yang ada pada channel YouTube Lazismu Pusat. Metode penelitian yaitu deskriptif kualitatif dengan pendekatan eksploratif. Hasil penelitian menunjukkan bahwa channel YouTube Lazismu Pusat memiliki profil dengan jumlah subscriber sebanyak 2.11K dan 396 postingan video. Channel YouTube Lazismu Pusat memiliki sembilan kolom seperti kebanyakan channel Youtube yang lain. Dari sembilan kolom, hanya delapan kolom (home, videos, shorts, live, community, channels, about dan search) yang dapat dianalisis secara eksploratif. Sementara kolom playlists tidak dapat dianalisis secara eksploratif.
Novel Carriers and Approaches Insight in Diabetes Mellitus
Authors: Sarna Rohit , Saxena Somesh , Bhardwaj Sudeep , Aggarwal Ashutosh 
Published: October 2023

Diabetes mellitus is one of the the most common, oldest and non communicable chronic disease in India.Diabetes is a serious, costly and heterogeneous metabolic disorder which ischaracterized by chronically elevated blood glucose levels (BGLs) and an inability to maintain BGL homeostasis. According to Indian council of medical research (ICMR, section 1,2005) diabetes is defined as a metabolic cum vascular syndrome of multiple etiologies factorise by hyperglycemia with disturbance of carbohydrate, protein and fat metabolism resulting from insulin deficiency or resistance to insulin or both.According to American diabetes association (ADA) diabetes is is defined as a group of metabolic diseases characterized by inappropriate hyperglycemia resulting from defects in insulin secretion, insulin action or both.
Alimentos de venta callejera en la ciudad de Villahermosa, Tabasco
Authors: Sánchez Ruíz Blanca Alicia , Centurión Hidalgo Dora , Espinosa Moreno Judith , Baeza Mendoza Lourdes , García Centurión José Alberto 
Published: October 2023

Los alimentos callejeros poseen una gran importancia socioeconómica ya que ofrecen una gran variedad de productos disponibles a un costo que no afecta la economía de las familias y que satisface sus necesidades de alimentación. En el estudio que da origen a esta obra se encontró que, en las calles de la ciudad de Villahermosa, Tabasco, México, se comercializan alrededor de noventa y tres productos obtenidos a través de diferentes tecnologías, como la de frutos y vegetales frescos cortados, extracción de jugos, infusiones, diferentes procesos de cocción (freído, asado, hervido, a la plancha, líquida), procesos de panificación y fermentación. Principalmente utilizan tecnologías tradicionales, como las de origen prehispánico, u ofrecen productos preparados en casa, en el lugar de venta o, semi preparadas, finalizadas en el puesto o punto de venta. Los vendedores utilizan medios de transportes adaptados para mantener la estabilidad de los alimentos, conservar la temperatura de los alimentos que requieren permanecer calientes o refrigerados. Los lugares donde se observó la venta de alimentos callejeros en la ciudad de Villahermosa fueron principalmente los parques, centros deportivos, oficinas, los cruceros de las calles, aceras de hospitales y de las avenidas comerciales. La oferta de productos está relacionada con las materias primas disponibles, los horarios de venta de productos, la estacionalidad y los hábitos alimentarios de la población. Se pueden encontrar desde puestos fijos hasta el uso de quioscos semifijos o móviles.
Anti-IL1 Therapy Does Not Affect the Response to SARS-COV-2 Vaccination and Infection in Patients with Systemic Autoinflammatory Diseases
Authors: Geck Leonie , Tascilar Koray , Simon David , Kleyer Arnd , Schett Georg , Rech Juergen 
Published: October 2023

Patients with sAID are a population at high risk of severe COVID outcomes but evidence on the efficacy of SARS-CoV-2 vaccination in this group of patients is scarce. To investigate the efficacy of SARS-CoV-2 vaccination in patients with systemic autoinflammatory diseases (sAID) receiving interleukin-1 inhibition is important. Vaccination responses from 100 sAID patients most of whom were treated with IL-1inhibitors (N=96) and 100 healthy controls (HC) were ana-lyzed. After 2nd SARS-CoV-2 vaccination, sAID patients showed similar anti-SARS-CoV-2 anti-body responses (mean (SD): 6.7 (2.7)) compared to HC (5.7 (2.4)) as well as similar neutralizing antibodies (85.1 ±22.9% vs. 82.5 ±19.7%). Anti-SARS-CoV-2 antibody responses and neutralizing antibodies were similar in sAID patients after SARS-CoV-2 infection and double vaccination. Furthermore, while antibodies increased after 1st and 2nd vaccination in sAID patients they did not further increase after 3rd and 4th vaccination. No difference was found in antibody responses between anakinra and anti-IL-1 antibody treatments and also the additional use of colchicine or other drugs did not impair vaccination responses.	Primary and booster SARS-CoV-2 vaccination lead to protective antibody responses in sAID patients, which are at the same level of vaccination responses in HC and in sAID patients after SARS-CoV-2 infection. Immunomodulatory treatments used in sAID do not seem to affect antibody responses to the SARS-CoV-2 vaccine.
PELATIHAN MANAJEMEN BANK SAMPAH BAGI MASYARAKAT DI KECAMATAN MUARA GEMBONG
Authors: Ramadhan Agphin Muhammad , Iriani Tuti 
Published: October 2023

This activity is a community service activity carried out by a team of lecturers and students of the Civil Engineering FT UNJ in collaboration with Muara Gembong sub-district and the Pantai Mekar village apparatus. Problems that occur in Muara Gembong are related to critical environmental conditions in coastal areas. Plastic waste that is scattered increasingly makes the environment irregular. This problem is a domino effect of the high level of abrasion in the region. The output target to be achieved is that the community gets knowledge about waste management through a waste bank. In addition, this activity can motivate people to manage waste. The waste bank system is expected to be effective in protecting the environment. This can be an additional income for the customers of the waste bank. The method of activity consists of the preparation and implementation stages. The preparation stage is in the form of regional observation and communication with partners. Then, the implementation phase is in the form of debriefing and training in waste bank management.

Abstrak
Pelatihan Manajemen Bank Sampah bagi Masyarakat di Kecamatan Muara Gembong, Kabupaten Bekasi, Provinsi Jawa Barat merupakan kegiatan pengabdian masyarakat yang dilakukan oleh tim dosen dan mahasiswa Rumpun Teknik Sipil FT UNJ bekerja sama dengan kecamatan Muara Gembong dan aparatur desa Pantai Mekar. Permasalahan yang ditemui berkaitan dengan kondisi lingkungan yang kritis di wilayah pesisir Muara Gembong. Sampah-sampah plastik yang berserakan semakin membuat lingkungan tidak teratur. Permasalahan ini merupakan efek domino dari semakin tingginya tingkat abrasi di wilayah tersebut. Target luaran yang ingin dicapai adalah masyarakat mendapatkan pengetahuan mengenai pengelolaan sampah melalui bank sampah. Selain itu, kegiatan ini dapat memotivasi masyarakat dalam mengelola sampah. Konsep bank sampah diharapkan selain menjaga lingkungan sekitar dapat pula menjadi tambahan pemasukan bagi para nasabah bank sampah. Metode kegiatan terdiri dari tahap persiapan dan pelaksanaan. Tahap persiapan yaitu berupa observasi wilayah dan menjalin komunikasi dengan mitra. Kemudian, tahap pelaksanaan berupa pembekalan dan pelatihan manajemen bank sampah.
Best Practices for Developing International Academic Partnerships in Orthopaedics
Authors: Brown Kelsey , Flores Michael J. , Haonga Billy , Chokotho Linda C. , O’Marr Jamieson M. , Rodarte Patricia , Shearer David , Morshed Saam 
Published: October 2023

Abstract:
Traumatic and nontraumatic orthopaedic conditions are major contributors to global morbidity and account for the majority of life-years lived with disability worldwide. Additionally, the burden of musculoskeletal injuries has increased substantially over the past 3 decades. Unfortunately, in low and middle-income countries (LMICs), access to orthopaedic care is limited, leading to a disproportionate burden of disease. The Lancet Commission on Global Surgery has emphasized the urgent need for unified international commitment and research collaboration to achieve universal access to safe and affordable surgical care. However, conducting high-quality orthopaedic research in LMICs remains challenging as a result of disparities in training, access to resources, infrastructure, and equipment availability. Partnerships between high-income countries (HICs) and LMICs have emerged in recent decades as an effective approach to combatting some of these challenges. These partnerships aim to bridge the gaps by facilitating collaborative research and knowledge exchange. The establishment of successful partnerships requires a collaborative and reciprocal approach that starts with a clear understanding of mutual research aims and the availability of resources. Despite the potential benefits, various factors can make establishing such partnerships difficult. However, these partnerships can have a substantial impact in delivering quality orthopaedic education and research training, thus improving access to care in resource-limited environments. This paper represents the collaborative effort of multiple international academic orthopaedic surgeons with extensive experience in HIC-LMIC partnerships. Our aims were to outline the best practices for conducting orthopaedic research within these relationships and to provide guidance for future successful collaborations.
Implementation of the LipIDens pipeline: assisted interpretation of lipid densities in membrane protein structures using simulations
Authors: Ansell T. Bertie , Song Wanling , Coupland Claire E. , Carrique Loic , Corey Robin A. , Duncan Anna L. , Cassidy C. Keith , Geurts Maxwell M. G. , Rasmussen Tim , Ward Andrew B. , Siebold Christian , Stansfeld Phillip J. , Sansom Mark S. P. 
Published: October 2023

Abstract
Interpretation of lipid and lipid-like densities surrounding membrane protein structures solved by cryo-electron microscopy (cryo-EM) is challenging. We developed the LipIDens pipeline for assisted structural interpretation of lipid densities using molecular dynamics (MD) simulations. This protocol details how to establish coarse-grained (CG) simulations of membrane proteins in biomimetic membranes, test lipid interaction cut-offs, calculate lipid interactions and binding sites, assess the quality of derived kinetics, compare lipid poses with structural densities, rank site lipids and refine lipid poses using atomistic simulations. These data provide a platform for identifying the most probable lipid accounting for a lipid-like density, assisting the modelling and interpretation of membrane protein structures.
Can mobilising specialists be relieved by a robotic system for the early mobilisation of intensive-care patients? A quantitative longitudinal study at three data collection points at a German university hospital
Authors: Mehler-Klamt Amrei , Koestler Natascha , Huber Jana , Warmbein Angelika , Rathgeber Ivanka , Gutmann Marcus , Biebl Johanna Theresia , Hübner Lucas , Schroeder Ines , Scharf Christina , Ohneberg Christoph , Kraft Eduard , Zoller Michael , Fischer Uli , Eberl Inge 
Published: October 2023

Abstract

Immobility in intensive-care patients can lead to significant health risks and costs for the health system. Reasons for this include the shortage of specialist staff in nursing and physiotherapy who typically handle mobilisation activities for intensive-care patients. The use of robotic systems aims to facilitate early mobilisation and thereby counteract prolonged immobility. Whether this can also alleviate the workload for staff has not yet been sufficiently investigated. To examine the psychological stress and behaviour of mobilising specialist during conventional and robot-assisted mobilisations of intensive-care patients and to draw conclusions regarding the impact on and relief for the mobilising staff due to the robotic system, a quantitative longitudinal study was conducted with two data collection points (T1, T2). Aspects of body posture, the perceived stress of mobilising staff, as well as the time and personnel required for mobilisation were collected through non-participatory standardized observations. Descriptive statistics were used for data analysis of the observations of 35 conventional mobilisations (T1) and 55 robot-assisted mobilisations (T2). Additionally, a follow-up was conducted for nine robot-assisted mobilisations to assess the routine use of the robotic system.
The duration of robot-assisted mobilisation had significantly longer process times in preparation, follow-up and execution phases compared to conventional mobilisation.
A significant correlation was found between the subjectively assessed feasibility of mobilisation and psychological stress (PSaR) experienced by the specialist staff during robot-assisted mobilisation. The more confident users felt in robot-assisted mobilisation, the less psychologically stress they perceived it.

Trial registration:
clinicaltrials.org TRN: NCT05071248, Date: 2021/10/21 URL https://clinicaltrials.gov/ct2/show/NCT05071248