bluuebunny/crossref_metadata_2025_split huggingface dataset:
FEATURES OF THE DETERMINATION OF ILLEGAL TREATMENT MEDICINES
Authors: Суровикина Анна Евгеньевна 
Published: January 2024

Статья посвящена причинам и условиям совершения преступлений, связанных с обращением фальсифицированных, недоброкачественных и незарегистрированных лекарственных средств и медицинских изделий. Устанавливается взаимосвязь и взаимозависимость наиболее полных знаний о детерминирующих признаков преступления со своевременностью и эффективностью предупреждения совершения преступных деяний.
The article is devoted to the reasons and conditions for committing crimes related to the circulation of counterfeit, substandard and unregistered medicines and medical devices. The relationship and interdependence of the most complete knowledge about the determining signs of crime with the timeliness and effectiveness of preventing the commission of criminal acts is established.
FORMATION OF THE SPHERES OF CHILDREN'S DEVELOPMENT OF THE LEONIE SERVICE
Authors: Чурилина Екатерина Владимировна , Жильцов Владимир Анатольевич 
Published: January 2024

Компания «Леони» разработала динамическую модель отслеживания и развития профессионально важных качеств (ПВК) человека. Модель включает диагностику, построение индивидуальной траектории развития, отслеживание динамики ПВК ребенка. Разработаны скрининговые тестирования, которые оценивают от 39 до 135 ПВК для разных возрастов. В работе показано, как были сгруппированы ПВК и сформированы сферы детского развития.
The Leoni company has developed a dynamic model for tracking and developing professionally important qualities of a person. The model includes diagnostics, building an individual development trajectory, and tracking the dynamics of the child's skills. Screening tests have been developed that evaluate from 39 to 135 professionally important qualities for different ages. The paper shows how the professionally important qualities were grouped and the spheres of child development were formed.
ИСКУССТВО И ДИЗАЙН. ЭСТЕТИЧЕСКИЙ ВЗГЛЯД
Authors: Аксенова Лариса Вадимовна , Орлова Елена Юрьевна 
Published: January 2024

В статье искусство, дизайн и их взаимодействие рассмотрены с точки зрения эстетики, освещено разнообразие мнений философов, исследующих процессы познания мира с позиции искусства, проанализирована эстетическая «почва» на момент появления в мировой культуре понятия дизайн; подчеркивается роль художественного творчества как уникального вида деятельности, имеющего множество аспектов и форм.
The article considers art, design and their interaction from the point of view of aesthetics, highlights the variety of opinions of philosophers who explore the processes of knowing the world from the standpoint of art, analyzes the aesthetic "soil" at the time of the emergence of the concept of design in world culture; emphasizes the role of artistic creativity as a unique activity with many aspects and forms.
FORMATION OF A SOCIAL AND VALUE ATTITUDE TOWARDS THE CHOSEN PROFESSION AMONG STUDENTS OF MEDICAL SCHOOLS
Authors: Мукаилова Альбина Мукаиловна 
Published: January 2024

В статье проанализированы проблемы формирования социально-ценностного отношения к профессии у обучающихся медицинских училищ. Изучена роль самостоятельной работы и различных сфер в процессе формирования ценностного отношения к профессии. Сделан ряд выводов о необходимости самостоятельной деятельности обучающегося, сотрудничества преподавателя и обучающегося в ходе образовательного процесса, опоры на методы самовоспитания и самообразования.
The article analyzes the problems of developing a social-value attitude towards the profession among medical school students. The role of independent work and various spheres in the process of forming a value attitude towards the profession has been studied. A number of conclusions have been made about the need for independent activity of the student, cooperation between teacher and student during the educational process, and reliance on methods of self-education and self-education.
Can large language models help augment English psycholinguistic datasets?
Authors: Trott Sean 
Published: January 2024

AbstractResearch on language and cognition relies extensively on psycholinguistic datasets or “norms”. These datasets contain judgments of lexical properties like concreteness and age of acquisition, and can be used to norm experimental stimuli, discover empirical relationships in the lexicon, and stress-test computational models. However, collecting human judgments at scale is both time-consuming and expensive. This issue of scale is compounded for multi-dimensional norms and those incorporating context. The current work asks whether large language models (LLMs) can be leveraged to augment the creation of large, psycholinguistic datasets in English. I use GPT-4 to collect multiple kinds of semantic judgments (e.g., word similarity, contextualized sensorimotor associations, iconicity) for English words and compare these judgments against the human “gold standard”. For each dataset, I find that GPT-4’s judgments are positively correlated with human judgments, in some cases rivaling or even exceeding the average inter-annotator agreement displayed by humans. I then identify several ways in which LLM-generated norms differ from human-generated norms systematically. I also perform several “substitution analyses”, which demonstrate that replacing human-generated norms with LLM-generated norms in a statistical model does not change the sign of parameter estimates (though in select cases, there are significant changes to their magnitude). I conclude by discussing the considerations and limitations associated with LLM-generated norms in general, including concerns of data contamination, the choice of LLM, external validity, construct validity, and data quality. Additionally, all of GPT-4’s judgments (over 30,000 in total) are made available online for further analysis.
Síndrome Disneico Afebril en Paciente Femenino de 59 Años con Múltiples Comorbilidades. Reporte de Caso
Authors: Banda Tapia Daniel Andrés , Castillo Guzmán Daniel Vicente , Pinzón Paladines Ana Belén , Saavedra Sarango Josselyne Adriana , Picoita Solórzano Pamela Johanna 
Published: January 2024

La insuficiencia renal aguda, la cirrosis hepática, la hiperplasia mieloide leve, la trombosis venosa profunda y la tromboembolia pulmonar aguda son condiciones médicas importantes. La insuficiencia renal aguda se caracteriza por la disminución súbita de la función renal. La cirrosis hepática es una enfermedad crónica del hígado que causa cicatrización y disfunción hepática. La hiperplasia mieloide leve involucra una alteración anormal de células mieloides en la médula ósea. Comprender y reconocer estas afecciones es fundamental para un diagnóstico y tratamiento adecuado, lo que puede mejorar los resultados clínicos y la calidad de vida de los pacientes.En el presente reporte de caso, Hija de paciente femenina de 59 años refiere que hace aproximadamente 2 semanas y sin causa aparente presenta disnea grado III, malestar general, tos productiva, diaforesis nocturna, distensión y dolor abdominal localizado en epigastrio y mesogastrio, difuso, EVA 7/10, que no cede al adoptar ninguna posición, y pérdida de peso de aproximadamente 5 kg. Además, refiere que desde hace 1 semana presenta parestesias de miembros inferiores y edema periférico ++++/4.
Estilos de Alimentación en Estudiantes en el Instituto Tecnológico Superior de Escárcega
Authors: Cervantes Sánchez Martha Elena , Neftali Benitez Humberto 
Published: January 2024

La alimentación es un factor determinante en la salud de los seres humanos. El alto consumo de azúcares simples, grasas trans y la poca actividad física contribuyen al deterioro físico del individuo a un corto o mediano plazo de tiempo dependiendo de la frecuencia y cantidad que se consuman este tipo de alimento y se lleve este estilo de vida. Por ello en la presente investigación se identificaron los estilos de alimentación en la comunidad estudiantil del Instituto Tecnológico Superior de Escárcega. Para el logro del trabajo se aplicó una encuesta en línea que se dividió en cuatro secciones misma que fue enviada a través de los correos electrónicos institucionales de los estudiantes. Los resultados muestran que un 50 % dijo comer de manera saludable de los cuales el 63% consumen sus alimentos en casa. Un factor importante a considerar en estos resultados es la economía y educación nutricional familiar y que la etapa juvenil o edad promedio de 19 años de los estudiantes contribuye a que las enfermedades crónicas relacionadas con la alimentación no son perceptibles.
Inhibition of Autophagy on Melatonin‑Induced Apoptosis in MCF-7 and MDA-MB-231 Cell Lines
Authors: ÖNDER Gözde Özge , BAYRAM Adnan , YILDIZ Oğuz Galip , YAY Arzu 
Published: January 2024

Aim: We looked at the connection between autophagy and apoptosis after our prior research indicated that melatonin could cause MCF-7 and MDA-MB-231 cells in the present study.
Material and Method: In order to investigate the autophagy inhibition’s effect on the melatonin-induced BC cells’ apoptosis, melatonin and/or 3-methyladenine (3-MA, autophagy inhibitor) have been utilized. Melatonin was applied to the cells following a 5-mM 3-MA pre-cultivation. Then, apoptosis was detected by the TUNEL method. The technique for double immunofluorescence labeling was used to identify the molecular alterations in Bax/Bcl-2 expression. To evaluate the cell viability, the MTT test was used.
Results: When an autophagy inhibitor, 3-MA, and melatonin treatment were co-administered in MCF-7 cells, apoptosis was decreased, compared to melatonin treatment alone, but it was not significant. In addition, 3-MA application downregulated Bax expression compared with melatonin alone treatment. Combined therapy markedly elevated apoptosis and significantly up-regulated Bax protein in MDA-MB-231 cells.
Conclusion: Taken together, in MCF-7 cells, autophagy’s inhibition contributes to the downregulation of apoptosis, whereas increased apoptosis is seen in MDA-MB-231 cells. Inhibiting autophagy in these cells treated with melatonin could serve as a self-defense mechanism, and This might be a good strategy for breast cancer adjuvant treatment.
Quality Assessment of YouTube Videos on Avascular Necrosis of the Femoral Head: An Analysis of Content, Reliability, and Educational Value
Authors: KILIÇ Ali İhsan , SAYER Gokhan , AKDEMİR Mehmet 
Published: January 2024

Aim: Videos related to avascular necrosis of the femoral head are no exception, and so the aim of this study is to evaluate the educational quality of YouTube videos on this topic.
Material and Method: A standardized video search was performed on YouTube using the terms “avascular necrosis of the hip”, “osteonecrosis of the hip” and “avascular necrosis of the femoral head”. The top 50 videos were then analyzed, and the characteristics and content of the videos were recorded. The Journal of American Medical Association criteria, The DISCERN score, The Global Quality Score and the new YouTube ‘Avascular Necrosis of the Femoral Head Score” were all used to assess the reliability and accuracy of the videos.
Results: The median video duration of the 50 videos was 10.85±19.17 minutes. The median number of views was 10,866 (range 221 to 278,174). According to the video content, 60% of the videos contained information about the disease, 10% were about patient experience, and the remaining 30% related to surgical technique or approach. Physicians were the primary uploader on YouTube for this topic. The rate of low-quality videos was determined as following according to the different evaluative systems: 68% according to the newly defined YouTube Avascular Necrosis of the Femoral Head Score, 60% according to the DISCERN score, and 56% according to The Global Quality Score. The Journal of the American Medical Association, The Global Quality Score, and DISCERN score were significantly correlated with video duration, while the New YouTube Avascular Necrosis of the Femoral Head Score was significantly correlated with video duration, time since upload, number of views, and like rate.
Conclusion: Most of the popular YouTube videos about avascular necrosis are of a low quality.
Rapid Generation of Kilonova Light Curves Using Conditional Variational Autoencoder
Authors: Saha Surojit , Williams Michael J. , Datrier Laurence , Hayes Fergus , Nicholl Matt , Kong Albert K. H. , Hendry Martin , Heng IK Siong , Lamb Gavin P. , Lin En-Tzu , Williams Daniel 
Published: January 2024

Abstract
The discovery of the optical counterpart, along with the gravitational waves (GWs) from GW170817, of the first binary neutron star merger has opened up a new era for multimessenger astrophysics. Combining the GW data with the optical counterpart, also known as AT 2017gfo and classified as a kilonova, has revealed the nature of compact binary merging systems by extracting enriched information about the total binary mass, the mass ratio, the system geometry, and the equation of state. Even though the detection of kilonovae has brought about a revolution in the domain of multimessenger astronomy, there has been only one kilonova from a GW-detected binary neutron star merger event confirmed so far, and this limits the exact understanding of the origin and propagation of the kilonova. Here, we use a conditional variational autoencoder (CVAE) trained on light-curve data from two kilonova models having different temporal lengths, and consequently, generate kilonova light curves rapidly based on physical parameters of our choice with good accuracy. Once the CVAE is trained, the timescale for light-curve generation is of the order of a few milliseconds, which is a speedup of the generation of light curves by 1000 times as compared to the simulation. The mean squared error between the generated and original light curves is typically 0.015 with a maximum of 0.08 for each set of considered physical parameters, while having a maximum of ≈0.6 error across the whole parameter space. Hence, implementing this technique provides fast and reliably accurate results.
Galaxy Quenching at the High Redshift Frontier: A Fundamental Test of Cosmological Models in the Early Universe with JWST-CEERS
Authors: Bluck Asa F. L. , Conselice Christopher J. , Ormerod Katherine , Piotrowska Joanna M. , Adams Nathan , Austin Duncan , Caruana Joseph , Duncan K. J. , Ferreira Leonardo , Goubert Paul , Harvey Thomas , Trussler James , Maiolino Roberto 
Published: January 2024

Abstract
We present an analysis of the quenching of star formation in massive galaxies (M
* > 109.5
M
⊙) within the first 0.5–3 Gyr of the Universe’s history utilizing JWST-CEERS data. We utilize a combination of advanced statistical methods to accurately constrain the intrinsic dependence of quenching in a multidimensional and intercorrelated parameter space. Specifically, we apply random forest classification, area statistics, and a partial correlation analysis to the JWST-CEERS data. First, we identify the key testable predictions from two state-of-the-art cosmological simulations (IllustrisTNG and EAGLE). Both simulations predict that quenching should be regulated by supermassive black hole mass in the early Universe. Furthermore, both simulations identify the stellar potential (ϕ
*) as the optimal proxy for black hole mass in photometric data. In photometric observations, where we have no direct constraints on black hole masses, we find that the stellar potential is the most predictive parameter of massive galaxy quenching at all epochs from z = 0–8, exactly as predicted by simulations for this sample. The stellar potential outperforms stellar mass, galaxy size, galaxy density, and Sérsic index as a predictor of quiescence at all epochs probed in JWST-CEERS. Collectively, these results strongly imply a stable quenching mechanism operating throughout cosmic history, which is closely connected to the central gravitational potential in galaxies. This connection is explained in cosmological models via massive black holes forming and growing in deep potential wells, and subsequently quenching galaxies through a mix of ejective and preventative active galactic nucleus feedback.
First Observational Evidence for an Interconnected Evolution between Time Lag and QPO Frequency among AGNs
Authors: Xia Ruisong , Liu Hao , Xue Yongquan 
Published: January 2024

Abstract
Quasiperiodic oscillations (QPOs) have been widely observed in black hole X-ray binaries (BHBs), which often exhibit significant X-ray variations. Extensive research has explored the long-term evolution of the properties of QPOs in BHBs. In contrast, such evolution in active galactic nuclei (AGNs) has remained largely unexplored due to limited observational data. By using the 10 new XMM-Newton observations for the narrow-line Seyfert 1 galaxy RE J1034+396 from publicly available data, we analyze the characteristics of its X-ray QPOs and examine their long-term evolution. The hard-band (1–4 keV) QPOs are found in all 10 observations and the frequency of these QPOs evolves ranging at (2.47–2.83) × 10−4 Hz. Furthermore, QPO signals in the soft (0.3–1 keV) and hard bands exhibit strong coherence, although, at times, the variations in the soft band lead those in the hard band (the hard-lag mode), while at other times, it is the reverse (the soft-lag mode). The observations presented here serendipitously captured two ongoing lag reversals between these two modes within about two weeks, which are first seen in RE J1034+396 and also among all AGNs. A transition in QPO frequency also takes place within a two-week timeframe, two weeks prior to its corresponding lag reversal, indicating a possible coherence between the transitions of QPO frequency and lag mode with delay. The diagram of time lag versus QPO frequency clearly evidences this interconnected evolution with hysteresis, which is, for the first time, observed among AGNs.
Revision of the Chironius bicarinatus complex (Serpentes: Colubridae): Redefined species boundaries and description of a new species
Authors: Sudré Vinícius , Andrade-Junior Albedi , Folly Manuella , Azevedo Josué A. R. , Ávila Robson Waldemar , Curcio Felipe Franco , Nunes Pedro M. Sales , Passos Paulo 
Published: January 2024

AbstractCurrently, the proposed diagnoses for theChironius bicarinatuscomplex reflect a wide variation in color pattern and pholidosis. Herein, we review theChironius bicarinatuscomplex based on morphological and molecular data from a sample of 485 specimens covering the species distribution. Our results corroborate the recognition ofC. bicarinatusandC. gouveai, and diagnose a distinct lineage without an available name. Thus, here we describe this new species restricted to the Baturité Massif, a relictual rainforest isolated in the Caatinga xerophytic domain, in the state of Ceará, northeastern Brazil. The new species can be distinguished from its congeners by its unique combination of qualitative and quantitative morphological characters (scale counts, morphometric, color pattern), and is also supported by molecular and ecological evidence. Additionally, we rectify data on the distribution and morphological variability ofC. gouveaito accurately infer the boundaries between this taxon andC. bicarinatus, which was not properly addressed. Finally, we discuss our results in the light of previous studies that suggest diversification hypotheses in the Atlantic Forest already detected for other taxa, highlighting the importance of conserving the areas of “Brejos de Altitude”, in northeastern Brazil, and the southern limit of Serra do Mar up to Serra do Tabuleiro, in southern Brazil.
The Flip Side
Authors: Wang Val 
Published: January 2024

THE FLIP SIDE presents the globalized circus world, where disparate people and acrobatic cultures come together, clash, and ultimately transform each other. The documentary showcases the coming-of-age of a Chinese circus artist who leaves home at age nine and goes on to perform with Cirque du Soleil and the 7 Fingers.
« THE FLIP SIDE »(« LE REVERS DE LA MÉDAILLE ») est une plongée dans le milieu du cirque mondialisé où des personnes et des cultures acrobatiques très différentes se rejoignent, s’opposent pour finalement se transformer les unes les autres. Le documentaire retrace l’entrée dans l’âge adulte d’un circassien chinois quittant sa famille à neuf ans pour rejoindre le Cirque du Soleil et le collectif Les 7 Doigts.
Repenser l’opposition entre game et play à partir des pratiques de « non-jeu »
Authors: Cayatte Rémi 
Published: January 2024

Cet article se penche sur une pratique de jeu paradoxale : le refus ou l’évitement de l’interaction avec une structure ludique préétablie. Ce type de performance s’observe chez des utilisateurs qui, en plus de ne pas jouer le jeu, ne jouent tout simplement pas au jeu, et qui remettent ainsi en question la possibilité même de médiation entre utilisateurs et systèmes de jeu. À travers l’étude de certains de ces exemples d’attitudes ludiques particulières, cet article propose également une réflexion sur la dualité entre play et game, sur l’utilisation habituelle de play pour qualifier le « jouer » au sens d’Henriot (1969), et sur l’idée que seule l’utilisation active d’un dispositif de communication permettrait d’accéder à un statut d’auteur.
La feuille de personnage : jeu de rôle, jeu de quantification
Authors: Javet David , Rochat Yannick 
Published: January 2024

Dans cet article, nous discutons et mettons en avant l’intérêt d’une réflexion motivée par un rapprochement analytique autour d’un unique élément ludique, celui de la feuille de personnage, particulièrement — mais non exclusivement — en lien avec le jeu de rôle sur table et sur écran. Nous explorons plus avant ce qu’est la feuille de personnage, soit ce que recoupe ce motif et comment il s’insère dans la pratique grâce à des exemples singuliers et variés, issus de formats et de modalités ludiques habituellement peu rapprochés, de manière à faire apparaitre son caractère adaptatif, pérenne et pervasif. Nous nous interrogeons enfin sur les êtres fictionnels que les feuilles de personnages offrent d’interpréter à partir de l’usage d’indicateurs numériques et sur les symboliques associées à ces manipulations de grandeurs. Sur le plan méthodologique, cet article vise également à offrir une démonstration d’analyse centrée sur le concept de motif ludique.
Le joueur et le musicien : approche philosophique des jeux instrumentés
Authors: Morisset Thomas 
Published: January 2024

Cet article part d’une comparaison courante, à la fois dans les discours universitaires et dans les propos de créateurs, entre les jeux vidéo et la musique, afin d’en examiner la pertinence et l’intérêt philosophique. Cette comparaison peut ainsi être comprise comme une image heuristique, comme un obstacle épistémologique ou bien comme marquant une réelle parenté entre ces pratiques. Ces trois valeurs sont pertinentes à différents niveaux de généralité, ce que montre l’étude des deux principaux enjeux mobilisés par ce rapprochement : « peut-on rapprocher un contrôleur ou un jeu vidéo d’un instrument de musique ? » et « est-ce que jouer à un jeu vidéo et jouer de la musique sont des activités ludiques suffisamment proches pour être rapprochées de manière non superficielle ? ».
Mise en onde et mise en monde
Authors: Meyer Charles 
Published: January 2024

À partir d’une analyse de l’introduction de Hellblade : Senua’s Sacrifice (2017, Ninja Theory), cet article propose d’interroger le rôle de l’interface sonore vidéoludique dans le développement, en cours de partie, de postures immersives et réflexives. Pour réaliser cette analyse, six fonctions sonores (systémique, de représentation spatiale, émotionnelle, narrative, ambiantielle et métacommunicationnelle) sont formalisées à partir d’une synthèse de recherches préalables. Dans le cadre de notre analyse, en articulant ces six fonctions au modèle sémiopragmatique de Roger Odin, nous montrons enfin l’oscillation favorisée par l’interface sonore entre une posture immersive et une posture réflexive du joueur ou de la joueuse. Au terme de l’article, nous qualifions cette oscillation de mise en onde, que nous envisageons comme une opération préalable à la mise en phase et qui est constitutive de l’aire intermédiaire d’expérience.