bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Local Angiotensin II/Angiotensin Type 1-receptor Mechanisms in Adipose Tissue Dysfunction to Promote Pancreatic Cancer
Authors: Khodashahi Rozita , Beiraghdar Fatemeh , Ferns Gorgon A. , Ashrafzadeh Kiayash , Aliakbarian Mohsen , Arjmand Mohammad-Hassan 
Published: February 2024

:
Obesity and adipose tissue dysfunction are important risk factors for pancreatic cancer.
Pancreatic cancer is one of the most lethal cancers globally. The renin-angiotensin system (RAS)
is expressed in many tissues, including adipose tissue. Dysregulation of angiotensin II and angiotensin
II receptors in adipose tissue through the activation of different signaling pathways leads
to adipose tissue dysfunction, including insulin resistance, adipose tissue inflammation, adipocytokines
secretion, and metabolic alterations. The pathogenesis of pancreatic cancer remains uncertain.
However, there is evidence that dysregulation of local angiotensin II in adipose tissue that occurs
in association with obesity is, in part, responsible for the initiation and progression of pancreatic
cancer. Due to the role of local angiotensin II in the dysfunction of adipose tissue, angiotensin
receptor blockers may be considered a new therapeutic strategy in the amelioration of the complications
related to adipose tissue dysfunction and prevention of pancreatic cancer. This review
aims to consider the biological roles of local angiotensin II and angiotensin II receptors in adipose
tissue dysfunction to promote pancreatic cancer progression with a focus on adipose tissue inflammation
and metabolic reprogramming.
Associated Factors Influencing Quality of Life and Knowledge Among Type 2 Diabetic Patients: A Cross-Sectional Study
Authors: Alsaraireh Mahmoud , Al-Kalaldeh Mahmoud , Alnawafleh Khaldoon , Dwairej Doa'a , Almagharbeh Wesam 
Published: February 2024

Background:
The assessment of the quality of life (QoL) among type 2 diabetic patients
is associated with different factors. Evidence shows that these patients usually suffer from
a lack of knowledge about the disease, inadequate self-care, and low QoL.

Objective:
The study aimed to assess knowledge of the QoL of type 2 diabetes patients and its
possible associated factors.

Methods:
This cross-sectional descriptive correlational study recruited type 2 diabetic patients
conveniently from out-clinics to achieve the objective of the study. The Diabetes Quality of Life
Brief Clinical Inventory (DQOL) and the Diabetes Knowledge Questionnaire 18 (DKQ-18)
along with a demographic questionnaire were used for patient assessment.

Results:
A total of 184 patients participated in the study. Patients' knowledge of diabetes was
found to be low (8.57 out of 18), with no statistical differences between male and female participants
(p=0.259). The average DQOL score was 2.87 out of 5, indicating moderate satisfaction
and self-care behavior. DKQ-18 and DOQL were found to be correlated (r= 0.216, p=0.003).
However, the patient’s age was found to be a significant factor that influences patients’ QoL
(F=4.27, p=0.040), whereas patients’ knowledge contributed weakly to the variation of QoL
(F=1.70, p=0.084).

Conclusion:
Irrespective of knowledge and educational background, the patient’s age is influential
in enhancing better QoL among type 2 diabetic patients.
Improvement in left ventricle geometry and function after kidney transplantation
Authors: Baiq Gerisa Rahmi Faharani  , Hasanah Mumpuni  , Yulia Wardhani  , Metalia Puspitasari  , Raden Heru Prasanto  , Iri Kuswadi  , Anggoro Budi Hartopo  
Published: February 2024

Chronic kidney disease (CKD) is associated with remodeling of the left ventricle (LV), affecting both its geometry and function. Kidney transplantation in patients with stage 5 CKD may lead to improvements in LV remodeling and result in better cardiac function. The aim of the study was to determine changes and improvements in LV geometry and function after kidney transplantation in patients with stage 5 CKD. This was an observational study conducted by collecting secondary data from the Hospital's Kidney Transplantation Registry, Dr. Sardjito General Hospital spanning the years 2017 to 2020. The study employed a comparative design, contrasting the results before and after treatment (kidney transplantation). We compared transthoracic echocardiographic parameters for LV geometry and function before and after kidney transplantation. The evaluation timeframe after kidney transplantation was divided into <12 and ³12 mo. A total of 27 patients qualified for inclusion in this study. In the <12 mon (n=20) evaluation group, there was a reduction in proportion of LV hypertrophy from 70% to 45%. There was an increase in global LV systolic function (ejection fraction) from 60.1±10.95% to 67.85±6.48% (p=0.014), and a decrease in LV diastolic dysfunction from 45% to 15% (p=0.07). In the ³12 mon (n=11) evaluation group, there was a decrease in the proportion of LV hypertrophy from 81.8 to 54.5%, an increase in global LV systolic function (ejection fraction) from 57.73±13.07% to 69.36±6.12% (p=0.011), and a decreased LV diastolic dysfunction from 63.6% to 0% (p=0.016). In conclusion, significant changes in LV geometry and function are observed following kidney transplantation, indicating improvements in these parameters. There are improvements in LV systolic function started at <12 mo and in LV diastolic function at ³12 mo after kidney transplantation.
Correlation between type of surgery and incidence of postoperative venous thromboembolism (VTE)
Authors: Supomo  , Budi Mulyono  , Usi Sukorini  , Adika Zhulhi Arjana  , Tandean Tommy Novenanto  
Published: February 2024

Venous thromboembolism (VTE) is a significant complication in patients after undergoing major surgery. The type of surgery is believed correlated with the incidence of VTE. This study aimed to evaluate the correlation between type of surgery and incidence of VTE among patients who underwent major surgery. It was a retrospective study conducted in Dr. Sardjito General Hospital, Yogyakarta using medical record data of patients who underwent major surgery and were diagnosed with VTE between 2016 and 2020. Patients were grouped by surgery type, and length of stay (LoS). All caused deaths were also analyzed. Among 29,120 patients who underwent major surgery, 76 (0.26%) experienced VTE with females patients accounting for 75%. The mean age of the patients was 55 yr. All VTE cases had the mean LoS of 25 d. The highest proportion of patients who experienced VTE were patients who underwent tumor removal (67.0%) followed by trauma patients (18.4%). A significant difference in the incidence of mortality between the surgical groups was reported (p = 0.02). Post-cardiology had the highest risk of mortality (OR=7.46; 95% CI: 0.322 - 172.61) while age had the lowest risk of mortality (OR=1.01; 95% CI: 0.953 - 1.071). In conclusion, surgery type is correlated with the incidence of VTE. Surgery due to cancer and trauma has a higher risk of VTE compared to the others.
Estudios de la Memoria y acciones de memoria en México. Dos caminos desfasados
Authors: Ruiz Lagier Rocío 
Published: February 2024

El presente trabajo busca dar cuenta del proceso que, actualmente, se está viviendo tanto en el campo de los estudios de la memoria como en el de las prácticas memoriales. Por medio del análisis de algunas acciones de memoria realizadas por colectivos de víctimas, se analizan aspectos centrales de los diversos procesos de construcción de memoria que han emergido en México. Las intervenciones y los actos de memoria que se exponen en este trabajo muestran la organización y la resistencia colectiva frente a la violencia. Pero también la diversidad de maneras y lugares desde los que se construyen las memorias.
Mechanical and Optical Characterization of Single-shade Resin Composites Used in Posterior Teeth
Authors: Oliveira HLQ , Ribeiro MTH , Oliveira G , Peres TS , Bragança GF , Silva GR , Soares CJ 
Published: February 2024

SUMMARY

Objectives
This study aimed to evaluate the optical and mechanical performance of two single-shade resin-based composites (RBCs) compared to those of a conventional RBC for restoring posterior teeth.

Methods
Two single-shade RBCs, Omnichroma (Tukoyama) and Vittra Unique APS (FGM), and a conventional RBC, Filtek Z350XT shade A2 (3M Oral Care), were evaluated in this study. The optical shade-matching performance was measured using a spectrophotometer. The light emitted by VALO Grand (Ultradent) and transmitted through the 2.0-mm RBC specimens was evaluated using beam profiling. Knoop hardness (KH, N/mm2), degree of conversion (DC, %) at the top and bottom, flexural strength (FS, MPa), elastic modulus (E, GPa), postgel shrinkage (Shr, %), and shrinkage stress (MPa) were evaluated. Scanning electron microscopy (SEM) was used to characterize the filler. Data for FS, E, and Shr were analyzed by one-way analysis of variance (ANOVA) and KH and DC by repeated one-way ANOVA measurement followed by Tukey test (α=0.05). The modified von Mises stress values, light transmission, and SEM images were analyzed qualitatively.

Results
All single-shade RBCs exhibited higher chromatic adaptation than the Filtek Z350XT (p&lt;0.001). Omnichroma exhibited less color difference than Vittra Unique APS, irrespective of the shade. The light transmitted through Omnichroma and Vittra Unique APS increased during polymerization. KH and DC values were significantly reduced from the top to the bottom of the specimens for all RBCs (p&lt;0.001); however, the ratio values were always higher than 80%. In general, all RBCs demonstrated similar mechanical properties. All RBCs exhibited a similar FS (p=0.083) and Shr value (p=0.144). Filtek Z350XT exhibited significantly higher E (p&lt;0.001) than both single-shade RBCs. All RBCs exhibited similar shrinkage stress during restoration and similar residual stress during occlusal loading.

Conclusions
Single-shade Omnichroma and Vittra Unique APS increased light transmission during light-activation, demonstrating better chromatic adaptation than conventional Filtek Z350XT. In general, Omnichroma and Vittra Unique APS exhibited similar mechanical properties and shrinkage stress distributions as Filtek Z350XT during light-activation and occlusal loading.
Occluding Efficiency of Different Desensitizing Agents and Er,Cr:YSGG Laser on Dentin Tubules
Authors: Uslu YS , Donmez N , Gungor AS , Akalin TT , Ulukapi H 
Published: February 2024

SUMMARY

Purpose
This study aimed to evaluate the effects of two desensitizers and the Er,Cr:YSGG laser on human dentin tubules, applied alone or in combination.

Methods
Ninety-six dentin specimens were obtained from extracted third molars and divided into six groups: Group 1: no-treatment (Control); Group 2: nano-hydroxyapatite desensitizer (NhapD); Group 3: NhapD+Er,Cr:YSGG laser (L); Group 4: Er,Cr:YSGG laser (L); Group 5: glutaraldehyde desensitizer (GD); and Group 6: GD+L, respectively. All specimens were evaluated using scanning electron microscopy. The diameter and the number of open dentin tubules, the tubules’ occluding ratio, and the mineral coverage area were measured via the Image J software at 2000× magnification. Atomic force microscopy was used to determine the blocking mechanism of desensitizing treatments and the surface morphology of dentin specimens. One-way ANOVA and Tukey tests were used for statistical analysis.

Results
The number of open tubules and the mean diameter of tubules for all treatment groups showed statistically significant differences from the control group The NhapD+L group had a significantly lower number of open tubules than the L and GD groups. The NhapD+L and L groups significantly had higher occluding ratios than the other groups.

Conclusions
The present study showed that the Er,Cr:YSGG laser alone was effective in terms of tubule occlusion and also contributed to increasing the occluding ratio of nano-hydroxyapatite. It may be recommended to use the Er,Cr:YSGG laser with nano-hydroxyapatite desensitizers to achieve effective tubule occlusion.
Shelf-life Estimation of Dried Chili in Vacuum Packaging
Authors: Ranawati Nanda Wisha , Ahmad Usman , Wulandani Dyah 
Published: February 2024

This research aimed to build a model for estimating the shelf life of dried chilies in vacuum packaging stored at any storage temperature. The shelf-life estimation of dried red chilies was carried out based on the change rate of dried chilies quality parameters using the ASLT (Accelerated Shelf-Life Testing) method with the Arrhenius approach. The shelf-life estimation using the ASLT method was carried out by conditioning the storage room, which could accelerate the degradation reaction, stored at temperatures above room temperature. Prior to storage, red chilies were dried until their moisture content reaches 10%. Then it was packaged in vacuum packaging made of PE (polyethylene) plastic and stored at 35°C. During the storage period, the observation was conducted on some quality parameters, namely moisture content, color, and vitamin C content. The same experiments were also carried out at 40°C, 45°C, and 50°C to obtain different rate constant values. The shelf-life estimation results from the Arrhenius equation model were selected based on the critical parameter, in this study the critical parameter was the decrease of vitamin C content. The shelf life of dried red chilies that were packed in vacuum stored at room temperature (25°C) could maintain its quality up to 365 days. Keywords: Arrhenius, ASLT, Red chili, Vacuum packaging, Shelf life,
Successful Multidrug Chemotherapy for Rhabdomyosarcoma in a Seven-Year-Old Girl: A Case Report
Authors: Abdullah Arwini Avissa , Ridha Nadirah Rasyid 
Published: February 2024

The most frequent soft tissue cancer in children is rhabdomyosarcoma (RMS). A diagnosis typically occurs between the ages of 5 and 6 in women. We report a seven-year-old girl was referred to Hospitals with complaints of a protruding left eye. The swelling was presented in July 2021, which was small earlier but has increased and become more prominent. An examination of the left eyelid showed a 2.5 x 2.5 x 1.5 cm solid mass with edema, erythema, and secretion in the superior and inferior affected eyelid. A Head CT scan revealed a left superolateral lacrimal duct tumour with a normal intracerebral structure. The histopathology examination found dacryoadenitis with an RMS tumour. This patient was treated using the RMS multidrug chemotherapy protocol (vincristine, actinomycin, and cyclophosphamide) for three sessions, which decreased tumour progressivity five months later. Early and appropriate treatment of this patient with chemotherapy regimens according to the protocol for RMS has a good prognosis.
UNPACKING RACIOLINGUISTIC IDEOLOGY IN YOUNG ADULT FICTION: A TEXTUAL ANALYSIS OF NOVEL “FRONT DESK” BY KELLY YANG
Authors: Nirwana  , Saifullah Aceng Ruhendi , Mustafa Mutakhirani , Amaliana MZ Zulfiana 
Published: February 2024

Abstract
This study examines the representation of raciolinguistic ideologies in Young Adult Fiction, with a particular focus on Kelly Yang's novel "Front Desk." The novel, which was published in 2018, serves as a prism through which to examine the interaction between race and language. Raciolinguistic ideologies, as described by Rosa and Flores, pertain to the complex interplay between race and language and how it is actively used to establish and perpetuate social hierarchies and inequalities. This study will use textual analysis to find and examine the linguistic and narrative mechanisms used in "Front Desk" to express and interrogate these raciolinguistic ideologies. The textual analysis results reveal unique linguistic techniques used in "Front Desk," offering light on how characters navigate and negotiate language in connection to their racial identities. The novel's narrative depictions quietly establish and perpetuate racial hierarchies, providing nuanced insights into how language contributes to these social constructions. The research clarifies the novel's portrayal of the progression of individuals' language practices in relation to their racial identities through an examination of character development, providing a greater understanding of raciolinguistic ideologies in narrative form.
Islamic Law Overview of Mu'athah Buying and Selling at STIBA Makassar
Authors: Hamka Baso , Wahid Haddade Abdul , Ambo Masse Abd. Rahman 
Published: February 2024

This study aims to determine the practice of mu'athah buying and selling at STIBA Makassar and elaborate the procedures and laws for carrying out each mu'athah buying and selling transaction without any supervision from the seller. This study used a qualitative descriptive research method with a phenomenological approach. The data collection methods used were observation, interviews, and documentation. The data sources in this study were STIBA Makassar students, sellers of refilled water gallons, buyers, lecturers, and administrators as informants; the sources of primary data and documents in the form of data or tables of information as the secondary data. The results found a basis for the philosophy of mu'athah buying and selling, which existed during the period of the Prophet Muhammad and his companions until now because the ulama would not have different opinions regarding the law if mu'athah buying and selling transactions never existed. The practice of mu'athah buying and selling at STIBA Makassar often involves theft, and the suspect tends to return the thing during the fifth semester and above. The law of mu'athah buying and selling is permissible according to most ulama based on the evidence from the QS. Ali-Imran/3:41 and a hadith narrated by a Jewish enslaved people. The problem that occurs from the practice of buying and selling at STIBA Makassar is not due to problems with the contract, but there are problems out of the contract; when the vendible is often lost, it means that there is a theft and it is illegitimate.
The Conception of Kafa'ah in Building a Harmonious Family for Hafidz Al-Qur'an Maslahah Perspective (Case Study on Alumni of the Majelis Qurra' Wal Huffadz As'adiyah Jami' Mosque Sengkang)
Authors: Miftahuddin Miftahuddin , Bakri Muammar , Santalia Indo 
Published: February 2024

This study aims to describe kafa'ah in building a harmonious family from a maslahah perspective by involving married alumni of the tahfidz al-Qur'an Majelis Qurra' Wal Huffadz As'adiyah Jami' Sengkang Mosque as research subjects through the stages of assessment; kafa'ah criteria, efforts to build a harmonious family and the conception of kafa'ah maslahah perspective in building a harmonious family. The research results show that the criteria for kafa'ah in building a harmonious family are dominated by; standard criteria on beauty and lineage, criteria on wealth, and social status. Both two criteria above will not be perfect without a review of the religious aspect, second, building a harmonious family from a maslahah perspective for hafidz al-Qur'an through the role of communication, appreciation, commitment, and spiritual aspects, financial stability, kafa'ah in religion and lineage, having the same goal, third, the conception of kafa'ah is shown; The Hufadz consistently say that the central concept of kafa'ah is seen from the religious and lineage aspects, marrying a partner who is equal in educational and social background, the context does not impose conditions such as the requirement to memorize the Qur'an thirty chapters.
Ibn Rushd's Epistemology of Ijtihad in the Completion of Fiqh Ikhtilaf (Study of the Book of Bidayah Al-Mujtahid, Chapter of Worship)
Authors: Fauzi Muhammad Rezky , Bakri Muammar , Shuhufi Muhammad 
Published: February 2024

This study analyzes the nature and concept of Ibn Rushd's ijtihad in completing fiqh ikhtilaf among the ulama. He is known for his expertise in philosophy, logic, medical, and the fields of jurisprudence and jurisprudence (Islamic law). It can be proven in his monumental work "Bidayah al-Mujtahid wa Nihayah al-Muqtasid." This study conducted descriptive library research based on a normative theological approach. This study collected data from the primary source of the book "Bidayah al-Mujtahid wa Nihayah al-Muqtasid" and other relevant and related secondary sources and then analyzed it using content analysis techniques. The study results showed that: 1) Ibn Rushd has a rich experience and scientific background. He referred to many sources in his ijtihad that mostly came from the book al-Istiz\kar by Ibn Abd al-Bar, so those books influenced some of Ibn Rushd's ijtihad decisions. Thus, Ibn Rushd cannot be considered an absolute mujtahid. 2) Generally, he is still guided by the ijtihad methodology outlined critically by the Ulama. Meanwhile, there are some approaches to solve the problem of ikhtilaf, such as first, the al-jam'u approach (compromise); second, al-tarjih (selecting among the most substantial arguments); third, al-jam'u baina al-jam'i wa al -tarjih (a combination of the al-jam'u and al-tarjih approaches); fourth, tawaqquf (silence); fifth, al-takhyir (optional).
The Concept of Wages in the Maqashid Sharia Overview (Study of PP No. 36 of 2021)
Authors: Wibawa Muhammad Dimas , Gassing Abd. Qadir , Hamsir Hamsir 
Published: February 2024

The objectives of this study are to: 1). Describe and analyze the concept of wages regulated by the government, 2). Discover workers/laborers response to government-regulated wages, and 3). Describe and analyze the government-regulated concepts based on the approach of the two main elements in maqashid sharia, such as hifzu an-nafs and hifzu al-māl. The author used a multidisciplinary approach to overcome the problems, namely a linguistic approach, normative juridical, and qualitative-descriptive methods to collect the data. This study was classified as library research; the data collected was analyzed using content analysis on literature that is representative and has relevance to the problem, then the comparison using comparative analysis was reviewed and concluded. After reviewing and analyzing policies in the form of established concepts, the wage provisions regulated by the government in law aim to provide a sense of justice for workers/laborers and align with the main principles in maqashid sharia. Even though Islam does not explicitly state the amount of wages in detail, it strictly requires anyone who provides work to pay wages/salaries to their workers. After reviewing the existing concepts, some problems were identified that need effort to resolve.