bluuebunny/crossref_metadata_2025_split huggingface dataset:
Iron status in Swiss adolescents with paediatric major depressive disorder and healthy controls: a matched case–control study
Authors: Osuna Ester , Baumgartner Jeannine , Wunderlin Olivia , Emery Sophie , Albermann Mona , Baumgartner Noemi , Schmeck Klaus , Walitza Susanne , Strumberger Michael , Hersberger Martin , Zimmermann Michael B. , Häberling Isabelle , Berger Gregor , Herter-Aeberli Isabelle ,   the Omega-3 Study Team, Albermann Mona , Nalani Kristin , Pick Oliver , Di Gallo Alain , Strumberger Michael , Contin Brigitte , Müller Stefan , Bachmann Silke , Wöckel Lars , Heitzer Simone , Rhiner Bruno , Yamini Amir , Erb Suzanne , Schmid Michael , Müller-Knapp Ulrich , Christodoulakis Ioannis , Seifert Burkhardt , Drechsler Renate , Grünblatt Edna , Hersberger Martin , Volleberg Martin , Hartling Ivan , Chakravarty Akash , Brunner Romuald , Drewe Jürgen , Braun Julia , Peterson Jenny 
Published: January 2024

Abstract
Purpose
Depression is associated with low-grade systemic inflammation and impaired intestinal function, both of which may reduce dietary iron absorption. Low iron status has been associated with depression in adults and adolescents. In Swiss adolescents, we determined the associations between paediatric major depressive disorder (pMDD), inflammation, intestinal permeability and iron status.

Methods
This is a matched case–control study in 95 adolescents with diagnosed pMDD and 95 healthy controls aged 13–17 years. We assessed depression severity using the Children’s Depression Rating Scale-Revised. We measured iron status (serum ferritin (SF) and soluble transferrin receptor (sTfR)), inflammation (C-reactive protein (CRP) and alpha-1-acid-glycoprotein (AGP)), and intestinal permeability (intestinal fatty acid binding protein (I-FABP)). We assessed history of ID diagnosis and treatment with a self-reported questionnaire.

Results
SF concentrations did not differ between adolescents with pMDD (median (IQR) SF: 31.2 (20.2, 57.0) μg/L) and controls (32.5 (22.6, 48.3) μg/L, p = 0.4). sTfR was lower among cases than controls (4.50 (4.00, 5.50) mg/L vs 5.20 (4.75, 6.10) mg/L, p < 0.001). CRP, AGP and I-FABP were higher among cases than controls (CRP: 0.16 (0.03, 0.43) mg/L vs 0.04 (0.02, 0.30) mg/L, p = 0.003; AGP: 0.57 (0.44, 0.70) g/L vs 0.52 (0.41, 0.67) g/L, p = 0.024); I-FABP: 307 (17, 515) pg/mL vs 232 (163, 357) pg/mL, p = 0.047). Of cases, 44% reported having a history of ID diagnosis compared to 26% among controls (p = 0.020). Finally, 28% of cases had iron treatment at/close to study inclusion compared to 14% among controls.

Conclusion
Cases had significantly higher systemic inflammation and intestinal permeability than controls but did not have lower iron status. Whether this is related to the higher rate of ID diagnosis and iron treatment in adolescents with depression is uncertain.
Swallowing improvement surgeries
Authors: Cotaoco Carmel , Ueha Rumi , Koyama Misaki , Sato Taku , Goto Takao , Kondo Kenji 
Published: January 2024

Abstract
Purpose
To discuss the different swallowing improvement surgeries that address one or more dysfunctional pharyngolaryngeal structures causing dysphagia. These surgeries reduce the risk of aspiration without sacrificing vocal function.

Methods
We searched the PubMed database and used Google Scholar search engine to find studies discussing the different swallowing improvement surgeries. A manual search of references in selected articles and reviews was done as well. No chronologic limitation was set for the studies; however, only articles written in English and Japanese were considered. Due to the nature of this article, no particular inclusion or exclusion criteria were set when searching for studies to be used as references; however, all relevant studies were reviewed and agreed upon by the authors for inclusion in this review article.

Results/discussion
Surgeries to improve swallowing function can be categorized into those that reinforce nasopharyngeal closure or pharyngeal contraction, improve laryngeal elevation or pharyngoesophageal segment opening, and those that improve vocal fold closure to protect the airway during swallowing. They are an effective alternative treatment that may significantly improve these patients’ quality of life. Swallowing rehabilitation with the altered pharyngolaryngeal structures is required post-operatively to significantly improve patients’ dysphagia.

Conclusions
Surgeries to improve swallowing function address specific dysfunctional sites involved in the swallowing mechanism. Choosing the most appropriate surgery for each patient requires knowledge of the pathophysiology for their dysphagia and detailed pre-operative work-up.
Efficacy and Safety of Re-administration of Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor (EGFR-TKI) After EGFR-TKI-Induced Interstitial Lung Disease (CS-Lung-005)
Authors: Kanaji Nobuhiro , Ichihara Eiki , Tanaka Takaaki , Ninomiya Takashi , Kozuki Toshiyuki , Ishikawa Nobuhisa , Nishii Kazuya , Shoda Hiroyasu , Yamaguchi Kakuhiro , Kawakado Keita , Toyoda Yuko , Inoue Masaaki , Miyatake Nobuyuki , Watanabe Naoki , Inoue Takuya , Mizoguchi Hitoshi , Komori Yuta , Kojima Kazuki , Kadowaki Norimitsu 
Published: January 2024

Abstract
Purpose
This study investigated the safety and efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) re-administration after recovery from EGFR-TKI-induced interstitial lung disease (ILD).

Methods
This multicenter retrospective study collected data from consecutive advanced NSCLC patients who underwent EGFR-TKI re-administration after recovery from EGFR-TKI-induced ILD.

Results
Fifty-eight patients were registered. The grades of initial TKI-induced ILD were grade 1 to 4. TKIs used for re-administration were erlotinib for 15 patients, osimertinib for 15, gefitinib for 14, afatinib for 13 patients, and dacomitinib for 1 patient. ILD recurred in 13 patients (22.4%), comprising 3 patients with grade 1, 6 patients with grade 2, and 4 patients with grade 3. No significant associations were found between ILD recurrence and age, smoking history, performance status, time from initial ILD to TKI re-administration, or concomitant corticosteroid use. However, the incidence of ILD recurrence was high in cases of repeated use of gefitinib or erlotinib or first time use of osimertinib at TKI re-administration. The ILD recurrence rate was lowest in patients treated with first time use of gefitinib (8%) or erlotinib (8%), followed by patients treated with repeated use of osimertinib (9%). The response rate, median progression-free survival by TKI re-administration, and median overall survival were 55%, 9.6 and 84.8 months, respectively.

Conclusion
This study showed that EGFR-TKI re-administration is a feasible and effective treatment for patients who recovered from EGFR-TKI-induced ILD. Our results indicate that re-administration of EGFR-TKI is an important option for long-term prognosis after recovery from EGFR-TKI-induced ILD.
Flourish, fight or flight: health in self-employment over time—associations with individual and business resources
Authors: Bernhard-Oettel Claudia , Bergman Louise , Leineweber Constanze , Toivanen Susanna 
Published: January 2024

Abstract
Purpose
Using COR theory to study developments of health and other key resources in self-employed workers in Sweden over 6 years, this study: (1) explored whether the heterogenous group of self-employed workers contained subgroups with different health trajectories, (2) investigated whether these were more typical for certain individuals (with respect to age, gender, sector, education, employment status), and (3) compared the different health trajectories regarding resource development in mental well-being, business resources, employment status, work ability.

Method
The study used data from the Swedish longitudinal occupational survey of health (SLOSH) and included participants working as self-employed or combiner (N = 2642).

Result
Five trajectories were identified with latent class growth curve model analysis (LCGM). Two health trajectories with (1) very good, respective (2) good stable health (together comprising 78.5% of the participants), (3) one with moderate stable health (14.8%), (4) one with a U-shaped form (1.9%), and (5) one with low, slightly increasing health (4.7%). The first two trajectories flourish: they maintained or increased in all key resources and were more likely to remain self-employed. Trajectories three and five consist of those who fight to maintain or increase their resources. Workers in the U-shaped health trajectory show signs of fight and flight after loss in health and other key resources.

Conclusions
Studying subgroups with different resource developments over time was suitable to understand heterogeneity in self-employed workers. It also helped to identify vulnerable groups that may benefit from interventions to preserve their resources.
Numerische Untersuchung von Skaleneffekten auf die Hydrodynamik in einem Buhnenexperiment
Authors: Glas M. , Tritthart M. , Pessenlehner S. , Sindelar C. , Buchinger M. , Baranya S. , Haimann M. , Habersack H. 
Published: January 2024

ZusammenfassungBuhnen werden im Wasserbau vielfach angewendet und sind aufgrund der komplexen Strömungsverhältnisse in Abhängigkeit von Wasserstand und Buhnengeometrie herausfordernd bezüglich der Wirksamkeit und der Eignung als flussbauliche Maßnahme. Physikalische Modellierungen werden seit etwa 130 Jahren im Wasserbau angewendet, bei Bedarf mit Feldmessungen und mittlerweile auch mit numerischen Modellen kombiniert, wodurch unter anderem auch die Bewertung von Buhnen profitiert. Aufgrund der Skalierung von physikalischen Modellen kann es jedoch zu Skalierungsfehlern kommen. In dieser Studie wurden fünf Buhnenvarianten an einem 1:1-Versuch und an einem skalierten Versuch im Maßstab 1:5 untersucht. 3D-numerische Modelle der Versuche wurden erstellt und anhand gemessener Werte kalibriert und validiert. Im Gegensatz zur modellierten Fließgeschwindigkeit konnten generell große Unterschiede in der modellierten turbulenten kinetischen Energie zwischen beiden Skalen identifiziert werden, welche auf einen Skalierungsfehler hindeuten. Die Unterschiede konnten auch beispielhaft in gemessenen Werten gefunden werden. Die Unterschiede waren größer, je niedriger der Wasserstand bzw. je höher die Buhnen waren. Diese Erkenntnisse geben einen Hinweis darauf, dass der gewählte Modellmaßstab von großer Bedeutung für die physikalische Modellierung im Wasserbau ist. Das neue Wasserbaulabor der Universität für Bodenkultur Wien ist für großmaßstäbliche Versuche bestens gerüstet. Eine detailliertere Untersuchung von Skalierungsfehlern bei physikalischen Modellversuchen von Buhnen und anderen Maßnahmen in Kombination mit noch präziseren numerischen Modellen ist in Zukunft jedenfalls zu empfehlen, um die Ursachen zu erforschen und deren Auswirkungen auf andere Aspekte, wie Sedimenttransport, Morphodynamik und Ökologie bewerten zu können.
Classification of intraarticular calcaneal fractures: comparison of two classification systems
Authors: Falis Mirosław , Bargiel Andrzej , Pyszel Krystian , Simon Patrick 
Published: January 2024

Abstract
Purpose
Accurately classifying displaced intraarticular calcaneal fractures (DIACFs) is essential for orthopedic surgeons to choose optimal treatment methods and provide results evaluation and communication. Many authors studying used Sanders classification reported moderate intra- and interobserver reliability. Taking the software opportunity of 3D virtual exarticulation, Goldzak updated French tri-dimensional Utheza classification, providing an alternative framework for classifying DIACFs. The aim of this study was to compare the intra- and interobserver reliability of Sanders versus Goldzak classification systems.

Methods
The CT scans of 30 patients with displaced intraarticular calcaneal fractures, treated in the same trauma center between 2014–2018, were analyzed by 16 medical doctors (specialists and residents in orthopedic surgery, specialists and residents in radiology), and classified according to Sanders and Goldzak classifications. The same images were sent on two separate sessions, in a randomized order. Interobserver reliability and intraobserver reproducibility were assessed using Kappa statistics and Gwet’s AC1 coefficient.

Results
Interobserver reliability using Gwet reported a value of 0.36 for Goldzak classification and 0.30 for Sanders classification (corresponding to “fair assessment” in both cases). In absence of subclasses, “substantial assessment” was reported for Goldzak classification (Gwet of 0.61) and “moderate assessment” for Sanders classification (Gwet of 0.46). Goldzak system had a greater interobserver reliability in the group of radiology residents. Intraobserver reliability coefficient was 0.60 for Goldzak classification and 0.69 for Sanders classification, indicating a substantial agreement for both classifications.

Conclusion
Despite the better view of the fracture lines provided by 3D reconstructions, this study failed to prove the superiority of Goldzak classification compared to Sanders classification for DIACFs.
A systematic review of current progress in community based vulnerability assessments
Authors: Smith Bethany , Diedrich Amy 
Published: January 2024

AbstractThis systematic literature review critically evaluates the extent to which community-based vulnerability assessments are progressing towards less siloed approaches that address spatial and temporal interactions and multiple exposures. The review focuses on studies that apply the most commonly operationalised frameworks in the livelihoods and climate change disciplines between 2014 and 2023, the Sustainable Livelihoods Framework (SLF) (n = 72) and the IPCC AR4 Framework (AR4) (n = 101). This review found that a minimal number of studies are addressing limitations. This was most significant in relation to the inadequate consideration of spatial scale (SLF 1%; AR4 5%), future temporal scale (SLF 4%; AR4 7%), and exposure to multiple shocks and stressors (AR4 7%; SLF 8%) within studies. Progress was seen with respect to overcoming siloed perspectives, which had previously led to the exclusion of external shock and stressor events (SLF) or socioeconomic factors (AR4) within assessments. Despite this progress, AR4 based studies were found to exclude key components of adaptive capacity, particularly in relation to natural (28%), financial (57%) and components of social capital. Additionally, only 47% of SLF based studies measured exposure to shock and stressor events. To overcome limitations scholars must engage with i) less-siloed frameworks that combine perspectives from the livelihoods and climate change disciplines and ii) non-static approaches that assess vulnerability in the context of social-ecological systems or use ethnographic methods (e.g., scenario planning and participatory mapping) to contextualise outputs. By engaging with these limitations, scholars reduce the potential for assessments to produce ineffective, or maladaptive outcomes.
Participatory justice and climate adaptation for water management in Small Island Developing States: a systematic literature review and discussion
Authors: Bailey Aisling , Moglia Magnus , Glackin Stephen 
Published: January 2024

AbstractAs the impacts of climate change increase, Small Island Developing States (SIDS) in particular shall face increasingly significant adaptation challenges. Past climate adaptation efforts within SIDS have had limited success. As such, the purpose of this systematic literature review has been to identify areas of importance for facilitating climate adaptation, particularly within Small Island Developing States (SIDS), and more specifically, to assess the extent to which participatory justice within decision-making processes is recognised as an important component of climate adaptation through the lens of water management. This review process utilised the SPIDER tool to guide the literature search across SCOPUS, Web of Science and EBSCO host databases, generating 495 publications that were reduced to a total of 70 sources guided by PRISMA, informing the review’s results and discussion. Thematic analysis of the selected studies was applied, utilising the Values-Rules-Knowledge framework. Through this analysis, five principles were created and comprise the major conclusions of this review: (1) ensuring community engagement, (2) expanding available options through local experimentation, (3) ensuring that monitoring and evaluation of adaptation initiatives are taken seriously, (4) adopting decision-making mechanisms that are systems-oriented and inclusive, and (5) investing only if there is a long-term commitment to protecting SIDS. It is hoped that these principles can serve as a comprehensive guide for funding agencies, applied projects and research aiding climate adaptation within SIDS.
Less brodifacoum in baits results in greater accumulation in the liver of captive Rattus norvegicus in a no-choice trail
Authors: Frankova Marcela , Radostna Tereza , Aulicky Radek , Stejskal Vaclav 
Published: January 2024

AbstractAnticoagulants are widely used as potent cumulative rodenticides; however, they are also associated with adverse environmental effects, such as intoxication of non-target animals. To ensure user safety, in the EU the use of anticoagulants containing active substances of > 30 ppm is restricted to professionals as these substances are toxic to reproduction Kat.1 A or B. Therefore, new products with < 30 ppm anticoagulant substance have been developed and registered. While the biological efficacy of these new products has been evaluated, the effect of their application on liver residues in targeted rodents was not examined before product introduction to the market. Our laboratory no-choice study on wild brown rats (Rattus norvegicus) showed that baits with high (50 ppm) and low (25 ppm) brodifacoum concentrations (with identical nontoxic cereal-based food components) presented 100% efficacy, although the 25 ppm bait exhibited significantly higher palatability and 4.5 times higher liver residues. Rats consumed 13.6 and 167.7 g of the 50 and 25 ppm baits, respectively, which corresponded to 3.16 and 14.91 μg/g of brodifacoum liver residues at their time of death. The experiments demonstrated that a decreased concentration of brodifacoum anticoagulant in rodenticide baits may lead to greater accumulation in rodent liver, thus indicating the urgent need to perform a detailed study of the environmental risks of low-concentration anticoagulant baits.
Comparing the cross-national impact of the COVID-19 pandemic on care received by community-dwelling older adults in 2020 and 2021: restoring formal home care versus polarizing informal care?
Authors: Tur-Sinai Aviad , Bentur Netta , Fabbietti Paolo , Lamura Giovanni 
Published: January 2024

AbstractThe COVID-19 pandemic has changed the supply of formal and informal home care to older adults in many countries across the world. This study aims to compare the initial picture of how the supply of formal and informal home care to older adults in European countries and Israel changed during the first pandemic year (from mid-2020 to mid-2021) and to examine the changes that these countries made in the provision of adequate care to older adults. Using data from the two COVID-19 waves of SHARE, we show that the provision of formal home care services improved in the investigated period, as in 2021 the share of those who reported difficulties in receiving formal home care dropped significantly compared to the previous year. By contrast, informal care provision patterns experienced a growing polarization, with some countries continuing in reporting a strong support from this source, and others moving towards a remarkable reduction in the help coming from informal networks. These findings can serve as a basis for the development of evidence-based recommendations that can inform future care policies at the national level and to implement more sustainable models for older adults living in the community.
Weighted and Choquet $$L^p$$ distance representation of comparative dissimilarity relations on fuzzy description profiles
Authors: Coletti Giulianella , Petturiti Davide , Bouchon-Meunier Bernadette 
Published: January 2024

AbstractWe consider comparative dissimilarity relations on pairs on fuzzy description profiles, the latter providing a fuzzy set-based representation of pairs of objects. Such a relation expresses the idea of “no more dissimilar than” and is used by a decision maker when performing a case-based decision task under vague information. We first limit ourselves to those relations admitting a weighted $$\varvec{L}^p$$

L

p

distance representation, for which we provide an axiomatic characterization in case the relation is complete, transitive and defined on the entire space of pairs of fuzzy description profiles. Next, we switch to the more general class of comparative dissimilarity relations representable by a Choquet $$\varvec{L}^p$$

L

p

distance, parameterized by a completely alternating normalized capacity.
“The Videos Made Me Feel Less Alone”: Feasible Executive Function Supports For Families
Authors: Smith Jessica V. , Dahlman Tennyson , Holmes Jessica , Armour Chelsea A. , Verbalis Alyssa , Ratto Allison B. , Hardy Kristina K. , Gunn Meredith , Decker Kaitlyn , Brown Dennard , Elliott Te’Andis , Werner Monica A. , Alexander Katie C. , Cannon Lynn , Anthony Bruno J. , Kenworthy Lauren , Anthony Laura G. 
Published: January 2024

AbstractExecutive function challenges are linked to important outcomes in adulthood, including mental and physical health and employment. Executive function skills can be taught but require support for generalization into home and school settings. The present study examined the feasibility of a series of brief videos (e.g., animations, expert and caregiver interviews) for caregivers of children with symptoms consistent with a neurodevelopmental disorder and flexibility or planning/organization problems. Caregivers (n = 102) viewed 12 videos over a four-month time period that describe ways to support and model executive function skills for their children. Quantitative and qualitative feedback suggest caregivers found the videos acceptable, feasible, and that they changed their view of their child’s EF challenges. In addition, caregiver knowledge of key executive function strategies and concepts improved. Results suggested these videos show promise to reduce caregiver-reported sense of strain and child executive function problems; however, caregiver competence did not improve from pre- to post-video review. These findings suggest even brief, online, and asynchronous caregiver-oriented instructional videos on executive function supports may improve caregiver and child outcomes. Moreover, they raise the possibility that low-cost, highly accessible caregiver support tools may yield important benefits for a common and potent childhood difficulty. Given the present study is a preliminary feasibility study of the caregiver support videos, future randomized controlled trials are necessary to fully examine caregiver- and child-related outcomes.