bluuebunny/crossref_metadata_2025_split huggingface dataset:
Proposal of the novel predictive model for postoperative pancreatic fistula in distal pancreatectomy for pancreatic tumor based on preoperative imaging parameters and stapler handling
Authors: Morino Koshiro , Nakano Kenzo , Goto Toshihiko , Tanaka Hirokazu , Machimoto Takafumi 
Published: February 2024

AbstractBackgroundDistal pancreatectomy (DP) using linear staplers is widely performed; however, postoperative pancreatic fistulas (POPF) remain an issue. This study aimed to analyze preoperative risk factors for POPF and assess stapler handling.MethodsWe retrospectively analyzed consecutive patients who underwent DP for pancreatic tumors using a linear stapler between 2014 and 2022. Preoperative measurements included pancreas‐to‐muscle signal intensity ratio (SIR) on fat‐suppressed T1‐weighted magnetic resonance imaging (MRI). The main outcome was clinically relevant POPF of the 2016 International Study Group of Pancreatic Fistulas definition. The predictive ability of the model was compared with the distal fistula risk score (D‐FRS) by using the area under the receiver operating characteristic curve (AUROC).ResultsAmong the 81 patients, POPF occurred in 31 (38.2%). Multivariate analysis identified computed tomography‐measured pancreatic thickness (odds ratio [OR] 1.30, 95% confidence interval [CI] 1.05–1.61, p = 0.009) and SIR on T1‐weighted MRI (OR 6.85, 95% CI 1.71–27.4, p = 0.002) as preoperative predictors. A novel preoperative model, “Thickness × MRI (TM)”‐index, was established by multiplying these two variables. The TM‐index exhibited the highest predictability preoperatively (AUROC 0.757, 95% CI 0.649–0.867). In the intraoperative variable analyses, TM‐index (p < 0.001), thin cartridge application (p = 0.032), and short pre‐firing compression (p = 0.047) were identified as significant risk factors for POPF. The model's AUROC combined with these two stapler handling methods was higher than D‐FRS (0.851 vs. 0.660, p = 0.006).ConclusionsThe novel preoperative model exhibited excellent predictability. Thick cartridge use and long pre‐firing compression were protective factors against POPF. This model may facilitate preventive surgical strategy development to reduce POPF.
Learning Projection-Based Reduced-Order Models
Authors: Ryckelynck David , Casenave Fabien , Akkari Nissrine 
Published: February 2024

AbstractIn this chapter, we introduce the solution space for high-fidelity models based on partial differential equations and the finite element model. The manifold learning approach to model order reduction requires simulated data. Hence, learning projection-based reduced order models (ROM) has two steps: (i) an offline step for the computation of simulated data and for consecutive machine learning tasks, (ii) an online step where the reduced order model is used as a surrogate for the high fidelity model. The offline step generates a train set and a validation set of simulated data. The accuracy and the generalisation of the reduced order model is evaluated in the online step by using a test set of data forecast by the high-fidelity model. The test set aims also to check the computational speedups of the reduced-order model compare to the high-fidelity model.
Industrial Application: Uncertainty Quantification in Lifetime Prediction of Turbine Blades
Authors: Ryckelynck David , Casenave Fabien , Akkari Nissrine 
Published: February 2024

AbstractIn this chapter, many of the concepts introduced in the previous chapters are applied to the uncertainty quantification of the lifetime prediction of turbine blades, generated by the uncertainty of the temperature loading field. A complete reduced-order model workflow is detailed, and the numerical experiments make use of the codes Mordicus and genericROM introduced in Chap. 4.
Mixed boundary conditions in AdS2/CFT1 from the coupling with a Kalb-Ramond field
Authors: Correa Diego H. , Ferro Maximiliano G. , Giraldo-Rivera Victor I. 
Published: February 2024

Abstract
The open string dual to a 1/6 BPS Wilson line in the $$ \mathcal{N} $$
N
= 6 super Chern-Simons-matter theory is coupled to a flat Kalb-Ramond field. We show that the resulting boundary term imposes mixed boundary conditions on the fields that describe the fluctuations on the world-sheet. These boundary conditions fix a combination of the derivatives of the fluctuations, parallel and transverse to the boundary. We holographically compute the correlation functions of insertions on the Wilson line in terms of world-sheet Witten diagrams. We observe that their functional dependence is consistent with the conformal symmetry on the line.
Impact of process parameters on improving the performance of 3D printed recycled polylactic acid (rPLA) components
Authors: Hasan Mohammad Raquibul , Davies Ian J. , Pramanik Alokesh , John Michele , Biswas Wahidul K. 
Published: February 2024

AbstractThe main goal of this research was to investigate the influence of additive manufacturing (AM) printing parameters on the mechanical properties and surface roughness of specimens fabricated using recycled polylactic acid (rPLA). In order to achieve this goal, significant printing parameters such as layer thickness, infill density, and nozzle temperature were selected based on prior research. A three-level L9 orthogonal array, based on the Taguchi method, was used in the experimental design. The mechanical properties of virgin PLA and recycled PLA printed specimens were examined and compared. To facilitate the analysis of variance (ANOVA) examination, the response data for mechanical and surface roughness parameters were transformed to signal-to-noise (S/N) ratios. The inspected responses under consideration were the surface roughness, shore D hardness, tensile strength, flexural strength, and impact strength. The main findings suggest that careful consideration of the layer height is crucial for achieving optimum mechanical properties in the recycled PLA specimens. Furthermore, the nozzle temperature also played an important factor that affected the mechanical and surface roughness properties of the 3D printed PLA specimens. Microscopic investigation demonstrated that the number and size of voids increased significantly when the layer thickness and temperature were low, namely, 0.1 mm and 195 ℃, respectively. Finally, the optimal combination of printing parameters for each performance characteristic was determined. Following this, a confirmation test was performed using the preferred combination of parameters, which indicated a strong correlation with the outcomes predicted statistically. The results obtained from this study revealed that recycled PLA exhibited mechanical properties comparable to that of virgin PLA under certain conditions. In summary, the results of this study will serve as a valuable dataset in the field of additive manufacturing, providing valuable insights for other researchers working with recycled PLA material.
Acoustic emission of kidney stones: a medical adaptation of statistical breakdown mechanisms
Authors: Eckstein Jack T. , Wiseman Oliver J. , Carpenter Michael A. , Salje Ekhard K. H. 
Published: February 2024

AbstractKidney stones have a prevalence rate of > 10% in some countries. There has been a significant increase in surgery to treat kidney stones over the last 10 years, and it is crucial that such techniques are as effective as possible, while limiting complications. A selection of kidney stones with different chemical and structural properties were subjected to compression. Under compression, they emit acoustic signals called crackling noise. The variability of the crackling noise was surprisingly great comparing weddellite, cystine and uric acid stones. Two types of signals were found in all stones. At high energies of the emitted sound waves, we found avalanche behaviour, while all stones also showed signals of local, uncorrelated collapse. These two types of events are called ‘wild’ for avalanches and ‘mild’ for uncorrelated events. The key observation is that the crossover from mild to wild collapse events differs greatly between different stones. Weddellite showed brittle collapse, extremely low crossover energies (< 5 aJ) and wild avalanches over 6 orders of magnitude. In cystine and uric acid stones, the collapse was more complicated with a dominance of local “mild” breakings, although they all contained some stress-induced collective avalanches. Cystine stones had high crossover energies, typically $$\sim$$
∼
750 aJ, and a narrow window over which they showed wild avalanches. Uric acid stones gave moderate values of crossover energies, $$\sim$$
∼
200 aJ, and wild avalanche behaviour for $$\sim$$
∼
3 orders of magnitude. Further research extended to all stone types, and measurement of stone responses to different lithotripsy strategies, will assist in optimisation of settings of the laser and other lithotripsy devices to insight fragmentation by targeting the ‘wild’ avalanche regime.
Dysphagia, health-related quality of life, and return to work after occipitocervical fixation
Authors: Singh Aman , von Vogelsang Ann-Christin , Tatter Charles , El-Hajj Victor Gabriel , Fletcher-Sandersjöö Alexander , Cewe Paulina , Nilsson Gunnar , Blixt Simon , Gerdhem Paul , Edström Erik , Elmi-Terander Adrian 
Published: February 2024

Abstract

Purpose
The purpose of this study was to evaluate patient-reported outcome measures (PROMS) on dysphagia, health-related quality of life (HRQoL) and return to work after occipitocervical fixation (OCF). Postoperative radiographic measurements were evaluated to identify possible predictors of dysphagia.

Methods
All individuals (≥ 18 years) who underwent an OCF at the study center or were registered in the Swedish spine registry (Swespine) between 2005 and 2019, and were still alive when the study was conducted, were eligible for inclusion. There was no overlap between the cohorts. Prospectively collected data on dysphagia (Dysphagia Short Questionnaire DSQ), HRQoL (EQ5D-3L) and return to work were used. Radiological and baseline patient data were retrospectively collected. In addition, HRQoL data of a matched sample of individuals was elicited from the Stockholm Public Health Survey 2006.

Results
In total, 54 individuals were included. At long-term follow-up, 26 individuals (51%) had no dysphagia, and 25 (49%) reported some degree of dysphagia: 11 (22%) had mild dysphagia, and 14 (27%) had moderate to severe dysphagia. On a group level, the OCF sample scored significantly lower EQVAS and EQ-5Dindex values compared to the general population (60.0 vs. 80.0, p = 0.016; 0.43 vs. 0.80, p < 0.001). Individuals working preoperatively returned to work after surgery. Of those responding, 88% stated that they would undergo the OCF operation if it was offered today. No predictors of dysphagia based on radiographic measurements were identified.

Conclusion
Occipitocervical fixation results in a high frequency of long-term dysphagia. The HRQoL of OCF patients is significantly reduced compared to matched controls. However, most patients are satisfied with their surgery. No radiographic predictors of long-term dysphagia could be identified. Future prospective and systematic studies with larger samples and more objective outcome measures are needed to elucidate the causes of dysphagia in OCF.
Effect of pressing pressure on the capacity of recycled graphite anode
Authors: Báňa Jiří , Čudek Pavel , Šedina Martin , Šimek Antonín , Kazda Tomáš 
Published: February 2024

AbstractDue to the increasing demand for lithium-ion batteries, there is an urgent requirement for environmentally friendly and efficient means of recycling these batteries. Graphite, a readily available and cost-effective material, tends to be neglected compared to more expensive metals such as cobalt or nickel. To achieve the new European targets, it will be necessary to focus on recycling even less valuable materials, such as graphite. Direct recycling of graphite represents an environmentally and economically viable solution. However, the capacity of recycled graphite depends on several factors, with pressing pressure being a potential variable. Within this article, we have focused on the impact of pressing pressure of spent graphite anode. The recycling was performed on the battery sample with a known lifetime history. It was found that when optimized, it is possible to achieve high stability and high capacities exceeding 300 mAh/g.
Graphical abstract
Investigating the Associations between Drought, Poverty, High-Risk Sexual Behaviours, and HIV Incidence in Sub-Saharan Africa: A Cross-Sectional Study
Authors: Trickey Adam , Johnson Leigh F. , Bonifacio Rogerio , Kiragga Agnes , Howard Guy , Biraro Samuel , Wagener Thorsten , Low Andrea , Vickerman Peter 
Published: February 2024

AbstractClimate change is increasing the likelihood of drought in sub-Saharan Africa, where HIV prevalence is high. Drought could increase HIV transmission through various mediating mechanisms; we investigated these associations. We used data on people aged 15–59 from Population-Based HIV Impact Assessment surveys from 2016 in Eswatini, Lesotho, Tanzania, Uganda, and Zambia. Survey data were geospatially linked to precipitation data for 2014–2016, with local droughts defined as cumulative rainfall between 2014 and 2016 being in < 15th percentile of all 2-year periods over 1981–2016. Using multivariable logistic regression, stratified by sex and rural/urban residence, we examined associations between (a) drought and poverty, (b) wealth quintiles and sexual behaviours (transactional, high-risk, and intergenerational sex), (c) sexual behaviours and recently acquiring HIV, and (d) drought and recent HIV. Among 102,081 people, 31.5% resided in areas affected by drought during 2014–2016. Experiencing drought was positively associated with poverty for women and men in rural, but not urban, areas. For each group, increasing wealth was negatively associated with transactional sex. For rural women, intergenerational sex was positively associated with wealth. Women reporting each sexual behaviour had higher odds of recent HIV, with strong associations seen for high-risk sex, and, for urban women, intergenerational sex, with weaker associations among men. Women in rural areas who had been exposed to drought had higher odds of having recently acquired HIV (2.10 [95%CI: 1.17–3.77]), but not women in urban areas, or men. Droughts could potentially increase HIV transmission through increasing poverty and then sexual risk behaviours, particularly among women in rural areas.
RNF115 aggravates tumor progression through regulation of CDK10 degradation in thyroid carcinoma
Authors: Zhu Jinxiang , Guo Longwei , Dai Hao , Zheng Zhiwei , Yan Jinfeng , Liu Junsong , Zhang Shaoqiang , Li Xiang , Sun Xin , Zhao Qian , Xu Chongwen 
Published: February 2024

Abstract
Background
RING Finger Protein 115 (RNF115), a notable E3 ligase, is known to modulate tumorigenesis and metastasis. In our investigation, we endeavor to unravel the putative function and inherent mechanism through which RNF115 influences the evolution of thyroid carcinoma (THCA).

Methods
We analyzed RNF115 expression in THCA using the Cancer Genome Atlas (TCGA) database. The influence of RNF115 on the progression of THCA was evaluated using both in vitro and in vivo experimental approaches. The protein regulated by RNF115 was identified through bioinformatics analysis, and its biological significance was further explored.

Results
In both THCA tissues and cells, RNF115 showed elevated expression levels. Enhanced expression of RNF115 fostered cell proliferation, tumor growth, and the exacerbation of epithelial-mesenchymal transition (EMT) in THCA, while also promoting tumor lung metastasis. Bioinformatics analysis identified cyclin-dependent kinase 10 (CDK10) as a downstream target of RNF115, which was found to be ubiquitinated and degraded by RNF115 in THCA cells. Functionally, overexpression of CDK10 was found to counteract the promotion of malignant phenotype in THCA induced by RNF115. From a mechanistic perspective, RNF115 activated the Raf-1 pathway and enhanced cancer cell cycle progression by degrading CDK10 in THCA cells.

Conclusion
RNF115 triggers cell proliferation, EMT, and tumor metastasis by ubiquitinating and degrading CDK10. The regulation of the Raf-1 pathway and cell cycle progression in THCA may be profoundly influenced by this process.
Bid-rigging in public procurement: cartel strategies and bidding patterns
Authors: Carbone Carlotta , Calderoni Francesco , Jofre Maria 
Published: February 2024

AbstractBid-rigging harms economies and societies. While existing research has primarily focused on quantifying the economic damages resulting from bid-rigging cartels, there is a relative dearth of studies exploring how firms interact and the specific techniques they use to rig tenders. Our paper examines the bidding behaviours associated with bid-rigging. Specifically, we investigate how cartel companies exploit legal opportunities, engage in joint and similar bidding and adapt tactics based on the number of colluding bidders. Our study relies on judicial evidence and a dataset of 1,242 companies (including 112 colluding entities) participating in 357 roadwork bid auctions in Italy. Through bootstrap logistic regressions, we analyse company-level indicators and their association with cartel involvement. The results reveal that cartels frequently exploit subcontracts and price similarity. Moreover, we find that bid-rigging tactics vary depending on the number of bidding cartel companies involved. When colluding companies are the majority of bidders, cartels rely on widespread member participation to cover a broad range of prices. Conversely, when cartel companies constitute less than half of the bidders, they tend to form temporary associations. These findings untangle the complexity inherent in cartel agreements and strategies, highlighting the importance of assessing firm interactions and relational patterns within co-bidding networks for a comprehensive understanding of collusive dynamics.
Material flow control in make-to-stock production systems: an assessment of order generation, order release and production authorization by simulation
Authors: Thürer Matthias , Fernandes Nuno O. , Lödding Hermann , Stevenson Mark 
Published: February 2024

AbstractMaterial flow control (MFC) is a key element of production planning and control. The literature typically categorizes different MFC methods according to how MFC is realized. This distinction overlooks that MFC decisions can be subdivided into three independent tasks that are executed as orders progress through the system: (i) order generation, (ii) order release, and (iii) production authorization. MFC methods are typically designed for only one of these three tasks, which leaves a large part of the order flow uncontrolled. This study therefore not only provides a new categorization of MFC methods, but also argues for the simultaneous application (or the combining) of three different MFC methods for order generation, order release, and production authorization. To support this argument, the performance effects of an integrated MFC approach are evaluated. Findings show that each individual MFC method impacts different performance metrics, which can be explained by the presence of a hierarchy of workloads, where each workload level constrains the succeeding hierarchical level. Each MFC method has a main impact on a different workload. This has important implications for the design of MFC methods and extends recent literature on hierarchical production planning and control systems.
Informal land leasing and social relations: Insights from Zimbabwe’s small scale farms
Authors: Marewo Malvern Kudakwashe 
Published: February 2024

AbstractThis article examines the role of social relations in enabling informal land leasing in Zimbabwe's small scale (A1 villagised) settlements after the Fast Track Land Reform Programme (FTLRP). After Fast Track Land Reform (FTLRP) in Zimbabwe, although some studies have explored informal land leasing, limited attention has been provided to the increasing informal subdivision in A1 villagised plots. The paper uses social relations as a basis for understanding the nature of informal land subdivisions, drawing insights from Zimbabwe’s small-scale farms in Zvimba District, Mashonaland West Province. Using qualitative insights, the article argues that in cases where land is provided through land reform, policy formulators should acknowledge the existence of these subdivisions for people with limited access to land. This article concludes that social relations enable people to access land through informal channels in resettlement areas enabling people to bypass legal policy directives through land subdivisions.
Assessing Impacts and Local Perceptions Following the Incidental Introduction of tilapia (Cichlidae: Cichliformes) in a Remote Inland Fishery in Papua New Guinea
Authors: Roeger Darcy L. , Amepou Yolarnie , Chin Andrew , Eisemberg Carla C. , Ibana Dotty , White William T. , Grant Michael I. 
Published: February 2024

AbstractIntroductions of non-native fish are intended to have positive social outcomes, although they can also result in negative environmental consequences. Recently, incidental introduction of tilapia (Oreochromis cf. niloticus) was recorded in the Kikori River, Papua New Guinea. This study investigated the abundance of Oreochromis cf. niloticus relative to native fish species in the Kikori Town market, and interviewed market vendors to gauge the local perception of Oreochromis cf. niloticus. Market data were collected over eight days with 1474 individual fish observed. Oreochromis cf. niloticus comprised 11.4% (n = 168) of fish and was the largest contributor of biomass (40.2%). Market vendors reported that Oreochromis cf. niloticus was easy to catch and sell, and ranked it highly in sale preference compared to native species. There is potential to explore export markets for Kikori River Oreochromis cf. niloticus in PNG’s highland provinces to expand economic opportunities for local communities.
Shared Care and Mothers’ Post-separation Economic Wellbeing in Finland and Wisconsin, US: Does Child Support and Sharing Child’s Costs Matter?
Authors: Haapanen Mari , Chanda Trisha , Miettinen Anneli , Riser Quentin H. , Bartfeld Judith , Hakovirta Mia 
Published: February 2024

AbstractChildren’s post-separation living arrangements may have important implications for mothers’ economic wellbeing. This study examines self-reported economic wellbeing of mothers with shared versus sole physical custody (also known as shared care) of the child six or more years since separation, using unique survey data on separated parents in Finland (n = 850) and Wisconsin, US (n = 395) in 2019–2020. We use sequential logistic regression models to examine the pathways through which this association potentially occurs—child support and sharing of children’s expenses between parents—and whether the outcomes differ by the family policy contexts of Finland and Wisconsin. Our findings suggest that Wisconsin mothers in shared versus sole physical custody arrangements have significantly lower levels of economic hardship, that are fully explained by greater cost-sharing with the other parent of the child. No such relationship is evident in Finland, although cost-sharing is independently negatively associated with economic hardship of Finnish mothers. Findings highlight how fathers’ contributions as tied to children’s living arrangements matter for post-separation economic wellbeing of mothers, and have implications for shared physical custody and child support policy.