bluuebunny/crossref_metadata_2025_split huggingface dataset:
Parental metabolic syndrome and elevated liver transaminases are risk factors for offspring, even in children and adolescents with a normal body mass index
Authors: Song Kyungchul , Yang Juyeon , Lee Hye Sun , Oh Jun Suk , Kim Sujin , Lee Myeongseob , Suh Junghwan , Kwon Ahreum , Kim Ho-Seong , Chae Hyun Wook 
Published: October 2023

IntroductionThe parent–child correlation in metabolic syndrome (MetS) and elevated transaminases is sparsely researched. We assessed the correlation of parental MetS and elevated transaminase status with these conditions in their children.MethodsData of 4,167 youths aged 10–18 years were analyzed in a population-based survey, and the parental characteristics were stratified by the presence or absence of MetS or alanine aminotransferase (ALT) elevation in their children. The prevalence of these conditions in children was analyzed according to their parents’ status. Logistic regression analyses were performed with MetS and ALT elevation in youth as the dependent variables.ResultsThe proportions of MetS and ALT elevation were higher in parents of children with MetS and ALT elevation than in those without, even among youths without obesity. In logistic regression analyses, age, body mass index–standard deviation score (BMI–SDS), and ALT elevation were positively associated with MetS, whereas age, male sex, BMI–SDS, protein intake, and MetS were positively associated with ALT elevation. Higher protein intake was related to ALT elevation, whereas metabolic components and nutritional factors were closely related in parents and their children. Odds ratios (OR) of ALT elevation for MetS was 8.96 even after adjusting nutritional factors in the children. The OR was higher for ALT elevation in the children of parents with MetS and ALT elevation compared to those without. ORs for MetS and ALT elevation in the children of parents with MetS were higher than those of children of parents without MetS, even after adjusting for nutritional intake. ORs for ALT elevation were higher in the children of parents with ALT elevation than those without, even after adjusting for nutritional intake and BMI of parents as well as the nutritional intake, age, sex, and BMI–SDS of the children.ConclusionMetS and elevated liver transaminase statuses in children were associated with those of their parents even after adjusting for nutritional factors, and the relationships were more prominent in the youth without obesity.
Ion channels in lung cancer: biological and clinical relevance
Authors: Capitani Chiara , Chioccioli Altadonna Ginevra , Santillo Michele , Lastraioli Elena 
Published: October 2023

Despite improvements in treatment, lung cancer is still a major health problem worldwide. Among lung cancer subtypes, the most frequent is represented by adenocarcinoma (belonging to the Non-Small Cell Lung Cancer class) although the most challenging and harder to treat is represented by Small Cell Lung Cancer, that occurs at lower frequency but has the worst prognosis. For these reasons, the standard of care for these patients is represented by a combination of surgery, radiation therapy and chemotherapy. In this view, searching for novel biomarkers that might help both in diagnosis and therapy is mandatory. In the last 30 years it was demonstrated that different families of ion channels are overexpressed in both lung cancer cell lines and primary tumours. The altered ion channel profile may be advantageous for diagnostic and therapeutic purposes since most of them are localised on the plasma membrane thus their detection is quite easy, as well as their block with specific drugs and antibodies. This review focuses on ion channels (Potassium, Sodium, Calcium, Chloride, Anion and Nicotinic Acetylcholine receptors) in lung cancer (both Non-Small Cell Lung Cancer and Small Cell Lung Cancer) and recapitulate the up-to-date knowledge about their role and clinical relevance for a potential use in the clinical setting, for lung cancer diagnosis and therapy.
Building our research administrator workforce as our clinical and translational research programs become increasingly complex
Authors: Kayla Calvo , Jennifer Phillips , Sandra Burks , Johnston Karen C. 
Published: October 2023

Introduction: Research administrators (RA’s) are critical members of the research workforce. For purposes of this article, research administrators are personnel who support the development, compliance, management, and financial oversight of sponsored research. There are currently very few institutional career development and mentoring programs available to research administrators. Recruitment and retention of quality research administrators has been especially challenging across the country in recent years.Methods: In an effort to address this gap in training and to increase recruitment and retention, the integrated Translational Health Research Institute of Virginia (iTHRIV), a collaborative NIH-NCATS funded Clinical Translational Science Award (CTSA) hub, has developed an innovative program of workforce development and mentoring for research administrators. This article provides an overview of one institutional training and development initiative, the Research Administration Program for Training and Resources (RAPTR). RAPTR provides training, resources and mentoring to develop a Community of Practice.Results: The program provides a forum where research administrators can share ideas, practices, and challenges.Discussion: This manuscript describes the benefits and lessons learned from our early experience in this program. We highlight selected components that may be generalizable to other institutions and describe individualized components, which require local policies and processes.
Drought response of water-conserving and non-conserving spring barley cultivars
Authors: Appiah Mercy , Abdulai Issaka , Schulman Alan H. , Moshelion Menachem , Dewi Elvira S. , Daszkowska-Golec Agata , Bracho-Mujica Gennady , Rötter Reimund P. 
Published: October 2023

IntroductionBreeding barley cultivars adapted to drought requires in-depth knowledge on physiological drought responses.MethodsWe used a high-throughput functional phenotyping platform to examine the response of four high-yielding European spring barley cultivars to a standardized drought treatment imposed around flowering.ResultsCv. Chanell showed a non-conserving water-use behavior with high transpiration and maximum productivity under well-watered conditions but rapid transpiration decrease under drought. The poor recovery upon re-irrigation translated to large yield losses. Cv. Baronesse showed the most water-conserving behavior, with the lowest pre-drought transpiration and the most gradual transpiration reduction under drought. Its good recovery (resilience) prevented large yield losses. Cv. Formula was less conserving than cv. Baronesse and produced low yet stable yields. Cv. RGT’s dynamic water use with high transpiration under ample water supply and moderate transpiration decrease under drought combined with high resilience secured the highest and most stable yields.DiscussionSuch a dynamic water-use behavior combined with higher drought resilience and favorable root traits could potentially create an ideotype for intermediate drought. Prospective studies will examine these results in field experiments and will use the newly gained understanding on water use in barley to improve process descriptions in crop simulation models to support crop model–aided ideotype design.
THE CHEMICAL ETCHING OF CdTe, ZnxCd1-xTe and CdxHg1-xTe SINGLE CRYSTALS WITH HNO3 – KI – DIMETHYLFORMAMIDE SOLUTIONS
Authors: Denysiuk R. , Tomashyk V. , Kaminskiy O. , Shelyuk I. , Pysarenko S. , Martsenyuk O. 
Published: October 2023

The chemical dissolution of CdTe single crystals, ZnxCd1-xTe and CdxHg1-xTe solid solutions in HNO3 – KI – dimethylformamide solutions has been investigated under reproducible hydrodynamic conditions for the first time. It is shown that the etching compositions of this system are cheaper, create a less aggressive environment, are more stable over time and are more ecologically safe. The diagrams «solution composition versus dissolution rate» has been plotted and the concentration limits of polishing etchant have been determined. Chemical-dynamic polishing with the investigated solutions can be carried out with a volume content of HNO3 9-15 %, while the polishing speed the surface of CdTe single crystals, ZnxCd1-xTe and CdxHg1-xTe solid solutions is within 1.6-2.5 μm/min. The dependence of the ions concentration that passed into the solution after the interaction of solid solutions ZnxCd1-xTe with the investigated etchants, versus the content of the oxidant in the etchant has been determined, and it was shown that the content of ions in the solution corresponds to the molar ratio in the semiconductor and indicates uniform dissolution of the surface. Based on the results of kinetic study, the apparent activation energy of the polishing was calculated for a solution of the composition (in vol. %): 12 НNO3 + 88 KI (DMF), which does not exceed 15.1 kJ/mol for СdTe and 7.7 kJ/mol for solid solutions on its basis, which indicates the limitation of the process by diffusion stages. The effect of the lactic acid and the nature of the semiconductors on the kinetics of chemical-mechanical polishing of the studied single crystals were determined. When the polishing solution is diluted with organic acid to 40 vol. %, the speed of chemical and mechanical polishing decreases from 3.5 to 0.5 μm/min. The compositions of etching mixtures and modes of implementation of chemical-dynamic polishing, which is recommended to be carried out in a suitable installation at the temperature 293 K and the disk rotation speed 82 min‑1, and chemical-mechanical polishing of the mention above semiconductor single crystals with the addition of lactic acid and polishing rates of 3.5-0.5 μm/min.
Gaddafi's Chemical Weapons: Chronicles of the Chadian-Libyan Conflict
Authors: Shilo N. I. 
Published: October 2023

The civil war in Chad has become one of the most protracted conflicts on the African continent. Its gradual internationalization led to the participation of three foreign military contingents in an internal armed confrontation Libya has taken an active military part in the civil war in Chad since 1972. There were several indications in certain studies about the use of chemical weapons by the Libyan troops. In the realities of the 1980s, these allegations could be true, or they could be an element of some information campaign against Libya. The purpose of this article is to verify the reports of the use of chemical weapons in Chad. Sources, methods. The sources for the study were the UN documents, declassified CIA materials and media reports. Cross-analysis of the documents, as well as the historical reconstruction of background events were carried out. Discussion of the results and conclusions. The analysis of the sources showed that, to date, no material evidence of the use of chemical weapons by Libyan troops in Chad has been found. There were no testimonies of direct witnesses and victims. No investigations have been carried out. Two sources of dissemination of information about the use of chemical weapons in northern Chad have been identified. The first one is the representatives of one of the participants in the civil war, Hissene Habré, who held the post of president in N'Djamena and fought against the Libyan troops. Representatives of H. Habré made such statements in December 1986. They cannot be considered reliable. In this way, one of the parties to the civil war wanted to show that Chad was the victim of the aggression with the use of weapons prohibited by the Geneva Protocol of 1925. However, it was established that in 1986 Libya did not possess chemical weapons. The second source is the CIA reports retransmitted to the public space in September 1987 about the alleged deliveries of chemical weapons to Libya from Iran. The reliability of these reports is doubtful. The «Iranian trace» has also not been proven. In 1987, during the Iran-Iraq war (1980-1988), chemical weapons were used against Iran, but the military-chemical potential of Iran itself has not been established. However, such an accusation organically fit into the policy of containment of «rogue states» pursued by the administration of US President Ronald Reagan. In this article, cross-analysis methods have been tested. They have shown their effectiveness in retrospective investigations.
Radiological Safety and Security Threats in Modern Conditions
Authors: Vasilkovsky E. V. , Dikun A. V. , Vasyukevich I. G. , Maltsev S. A. , Veber E. V. , Kuzhelko S. V. 
Published: October 2023

The lecture is intended to prepare military specialists in the field of nuclear and radiation safety and security for the Armed Forces of the Russian Federation, as well as to train officials responsible for organizing and ensuring radiation safety in military units and organizations of the Ministry of Defense of the Russian Federation.The lecture addresses two study questions:1) The main external threats in the sphere of radiological safety.2) The main internal threats in the sphere of radiological safety.
Analisis Efektivitas Penggunaan System Console pharmacy terhadap Pembelian Obat Rawat Jalan Non Racikan di RS Premier Jatinegara
Authors: Aprilia Pita , Andriani Helen 
Published: October 2023

Hospital pharmacies are responsible for managing and monitoring the drug use process and ensuring the safe, effective, economical and timely availability of drugs to patients and hospital staff. The waiting times indikator set by the Hospital for non-compound drugs is less than 20 minutes with a target delay less than 10%. However, during the period July 2021 to June 2022, 56,77% of the drugs were prepared beyond 20 minutes. The Pharmacy Department and hospital manajemen decided to improve the manajemen of outpatient drug purchase queues by using an automated prescription queuing system (pharmacy console). Analyze the effect of using the console pharmacy system for outpatients purchase of non-compound drugs in terms of decreasing the percentage of delays when non- compound drugs are received by patients exceeding 20 minutes and increasing the number of line itemss in outpatient pharmacy. Analysis data of non-compound drugs delay report and the number of line itemss report in outpatient pharmacy in the period July-December 2022 after using the console pharmacy system. The number of prescriptions delayed more than 20 minutes decreased from a monthly average of 56.77% to 36.54%, a decrease of 20.23% per month. The number of Pharmacy line itemss also increased from the average per month in the previous period of 45,415 to 53,945 or an increase of 8,531 per month. Even though it still has not reached the target, the console pharmacy system has proven to be effective in providing many advantages for Premier Jatinegara Hospital in reducing waiting times and increasing the purchase of non-compound drugs in outpatients pharmacy. Pharmacy Departments and hospital manajemen must continue to work together for continuous improvement.
Investigating the factor influencing Indonesian Consumers' Intention to Purchase Green Products in Indonesia: Applying the Theory of Planned Behavior
Authors: Aisyah Dinda Dewi , Cahyasita Dhika 
Published: October 2023

Green products have received worldwide attention as an alternative to more environmentally responsible consumption. Even though the environmental sustainability of green products is crucial, more research is still needed to determine the factors influencing consumer purchasing behavior for green products in developing nations, particularly Indonesia. Using the Theory of Planned Behaviour (TPB), this study investigates the psychological aspects that influence green behavior. It is believed that attitude, perceived behavioral control (PBC), and subjective norm all substantially impact a consumer's decision to purchase a green product. Subjective norm is the influence of people surrounding the respondent, while PBC is the respondent's perspective about their ability to perform certain actions. The research was conducted in 2023 using an online survey. Partial Least Square-Structural Equation Modelling (PLS-SEM) was used to analyze the data of 228 respondents using SmartPLS 3. The results show that attitudes and PBC significantly influence green consumption behavior. However, they show small predicting powers towards the intention. The subjective norm does not directly influence how behavior is formed but directly impacts how customers' attitudes are formed. The research results provide practical implications for the government and marketers to hold a special exhibition for green products and create labeling to improve the accessibility of green consumption. At the same time, the government can contribute to supporting green consumption by labeling pro-environmental products. This research still uses the basic variables of the TPB, where many researchers can add other variables that have the potential to influence a person's intention to take an action.
تأثير انموذج درايفر في تعلم بعض المهارات الأساسية بالكرة الطائرة للطلاب
Authors: جبار نور الهدى , داود سوزان 
Published: October 2023

المستخلص
هدفت الدراسة التعرف على تأثير انموذج درايفر في تعلم المهارات موضوعة البحث. اما فرضية البحث هناك فروق ذات دلالة إحصائية بين نتائج الاختبار القلبي والبعدي للمجموعتين الضابطة والتجريبية في تعلم أداء بعض المهارات بالكرة الطائرة. استعملت الباحثتان منهج البحث التجريبي وبأسلوب المجموعتين التجريبية والضابطة ، تكونت عينة البحث من شعب طلاب المرحلة الثانية والبالغ عددهم (10) شعب حيث تم اختيار (3) شعب وهم (ه، ز، ي) إذ اختارت الباحثة شعبة (ي) للتجربة الاستطلاعية والبالع عددهم (33) وشعبة (ه) المجموعة التجريبية (انموذج درايفر) والبالع عددهم (28) وشعبة (ز) المجموعة الضابطة والبالع عددهم (30) وبعدها قامتا الباحثتان بأختيار متغيرات البحث اختبارات تقويم الأداء واجراء التجارب الاستطلاعية ووضع التمرينات من خلال انموذج درايفر وقامتا ايضاً بالاختبارات القبلية والبعدية للحصول على النتائج ومعالجتها احصائياً ومن ثم استخراج النتائج ومن خلال الأخيرة استنتجتا الباحثتان وهي: ان استخدام نموذج تعليمي معتمدة على تسلسل وتطبيق يتخلله ترتيب يؤدي الى تعلم المهارات بالكرة الطائرة. وإدخال النموذج التعليمي الذين اقترحته الباحثتان ضمن تعليم المهارات بالكرة الطائرة. الكلمات المفتاحية: الكرة الطائرة، النماذج التعليمية، المهارات
Evaluation of Psychosocial Risk Factors and Emotional Intelligence
Authors: Rueda Espinoza Kati Maribel , Cordero Alvarado Narcisa Isabel , Álvarez Cadena Kerly Ángela , Vaca Gallegos Ana Marina 
Published: October 2023

The aim of this study was to adapt and validate the results of the Battery of Instruments for the Evaluation of Psychosocial Risk Factors developed by the Ministry of Social Protection of Colombia in 2010 for workers in Ecuador. An instrumental study was conducted with 3172 workers, and the psychometric properties were analyzed using expert criteria, construct validity analysis using exploratory factor analysis and reliability analysis using internal consistency with Cronbach's Alpha coefficient.
More about the semantic approach to NLP problem solving
Authors: Гордей А.Н. 
Published: October 2023

Новый подход к семантической разметке события и формализации синтаксиса английских, китайских и русских предложений на основе третьей редакции второй версии Теории автоматического порождения архитектуры знаний (ТАПАЗ‒2) вновь рассматривается ретроспективно и проспективно в контексте современных проблем информационно-поисковых и информационно-решающих систем и интеллектуализации веба .A new approach to the semantic markup of an event and the syntax formalization of English, Chinese and Russian sentences based on the third edition of the second version of the Theory for Automatic Generation of Knowledge Architecture (TAPAZ‒2) is again considered retrospectively and prospectively in the context of modern problems of information retrieval and information decision systems and web intellectualization.
Intertextuality, Interdiscursivity, Intermediality: how to describe intra and intersemiotic interactions in the arts as communication
Authors: Логинова Е.Г. 
Published: October 2023

В статье рассматриваются разного рода внутри- и межсемиотические взаимодействия в художественной коммуникации. В качестве материала используются драматургические произведения С. Беккета, Л. Андреева, В. Маяковского, Е. Шварца, Д. Данилова и др., театральные и киноинтерпретации пьес. Анализ референциальной области терминов «интертекстуальность», «интердискурсивость», «интермедиальность», используемых в научных работах для описания внутри- и межсемиотических взаимодействий, проводится с учетом того, что становится предметом изучения в каждом конкретном случае. В статье обосновывается использование термина «интермедиальность» в отношении театральных и кинопостановок пьес, включающих визуальные и текстовые цитаты для создания образности; уточняются контекстуальные возможности использования соположенных терминов «интертекстуальность» и «интердискурсивность».
The article focuses on different types of intra and intersemiotic interactions that take place in the arts as communication. The aim of the research is to specify three notions used to describe intra and intersemiotic transformations, references and parallels, namely: intertextuality, interdiscursivity, intermediality. The author makes an attempt to define similar, as well as unique, characteristics of intertextual, interdiscursive and intermedia processes in the theatrical performance viewed as one more modelling system after a play as a secondary modelling system according to Yu. Lotman. The theoretical assumptions are illustrated with the help of plays written by Russian and British playwrights of the 20thand the 21st c. (S. Beckett, V. Mayakovskij, L. Andreev, E. Shwarts, D. Danilov, etc.), theatrical and cinematic performances based on these plays. The results prove that the notion of intermediality can be used in relation to theatrical discourse in which different semiotic systems (theatrical codes, media) are interconnected in order to enhance semantic projections and achieve desirable pragmatic and aesthetic effects. The notions of intertextuality and interdiscursivity have similar reference domains, intertextuality having a wide scope of meaning.
VAJİNAL ENFEKSİYONLARIN KADINLARIN GÜNLÜK YAŞAMINA ETKİSİ VE ALTERNATİF TEDAVİ YAKLAŞIMLARI
Authors: AKBULUT Nazan , DAŞIKAN Zeynep 
Published: October 2023

Üreme sisteminin yapısını oluşturan savunma mekanizmalarının mikroorganizmalar tarafından bozulması ile üreme sistemi enfeksiyonları oluşur. Yetişkin kadınlarda oldukça sık görülen üreme sistemi enfeksiyonları kadınların poliklinik başvuruları arasında en sık karşılaşılan şikayetler arasında yer almaktadır. Bu enfeksiyonlardan biri olan vajinitler; vajinanın enfeksiyonu veya inflamasoyunudur. Vajinitler; vajinal akıntı, kaşıntı, yanma, irritasyon, ağrı ve kötü koku ile karakterizedir. Tedavi edilmedikleri zaman pelvik inflamatuar hastalığa neden olabilir. Bu durum ise infertilite, ektopik gebelik, preterm doğum ve düşük doğum ağırlıklı bebek, koryoamnionit gibi komplikasyonlara neden olabilir. Tüm bu şikayetler kadınların üreme sağlığı ve cinsel sağlığını, yaşam kalitesini hatta psikolojisini olumsuz yönde etkilemektedir. Vajinit tanısı alan kadınların günlük yaşamı da son derece kötü etkilenmektedir. Yapılan çalışmalarda kadınlar vajinit semptomlarında dolayı negatif bir beden imgesi, düşük benlik saygısı ve hayal kırıklığı ile umutsuzluk hisleri ile beraber üzgün ve depresif hissettiklerini ifade etmişlerdir.
Son derece basit ve kadının hayat döngüsü boyunca en az bir kez karşılaştığı bu enfeksiyonlara kanıt temelli güncel alternatif ve tamamlayıcı tedavilerin etkisi de son yıllarda yadsınamaz düzeydedir. Literatüre bakıldığında vajinit tedavisinde genital hijyen uygulamaları, probiyotik/yoğut, propolis kullanımı ile bitkisel tedaviler ve mikrobiyota çalışmaları ön plana çıkmaktadır. Vajinal enfeksiyonların yönetiminde hemşirenin birincil rolü, riskli sağlık davranışlarını değiştirmek, vajinal enfeksiyonların ortaya çıkmasını ve tekrarlamasını önlemek güncel literatürü takip ederek eğitim ve danışmanlık vermektir.