bluuebunny/crossref_metadata_2025_split huggingface dataset:
The GAPS Programme at TNG
Authors: Claudi R. , Bruno G. , Fossati L. , Lanza A. F. , Maggio A. , Micela G. , Maldonado J. , Benatti S. , Biazzo K. , Bignamini A. , Cabona L. , Carleo I. , Danielski C. , Desidera S. , Malavolta L. , Mancini L. , Montalto M. , Nardiello D. , Rainer M. , Scandariato G. , Sozzetti A. , Cosentino R. , Covino E. , Di Fabrizio L. , Ghedina A. , Lorenzi V. , Molinari E. , Molinaro M. , Pagano I. , Piotto G. , Poretti E. 
Published: November 2023

Context. Stellar activity is the most relevant types of astrophysical noise that affect the discovery and characterization of extrasolar planets. On the other hand, the amplitude of stellar activity could hint at an interaction between the star and a close-in giant planet. Progress has been made in recent years in understanding how to deal with stellar activity and search for observational evidence of star-planet interactions.
Aims. The aim of this work is to characterize the chromospheric activity of stars hosting short-period exoplanets by studying the correlations between the chromospheric emission (CE) in the Ca II H&K and the planetary parameters.
Methods. We measured CE in the Ca II H&K lines using more than 1900 high-resolution spectra of a sample composed of 76 targets, observed with the HARPS-N spectrograph between 2012 and 2020. We transformed the fluxes into bolometric- and photospheric-corrected chromospheric emission ratios, R′HK. Furthermore, we completed the sample of hosts digging for data in previous works. Stellar parameters Teff, B–V, and V were retrieved homogeneously from the Gaia DR3. Then, M★, R★, and ages were determined from isochrone fitting. We retrieved planetary data from the literature and catalogs. The search for correlations between the log(R′HK) and planetary parameters have been performed through both Spearman’s rank and its statistics as well as the more sophisticated Gaussian mixture model method.
Results. We found that the distribution of log(R′HK) for the transiting planet hosts is different from the distribution of field main-sequence and sub-giant stars. The log(R′HK) of planetary hosts is correlated with planetary parameters proportional to the planetary radius to the power of n (RPn, indicating a common origin for the correlations. The statistical analysis has also highlighted four clusters of host stars with different behavior in terms of their stellar activity with respect to the planetary surface gravity. Some of the host stars have a value of log(R′HK) that is lower than the basal level of activity for main sequence stars. The planets of these systems are very close to filling their Roche lobe, suggesting that they evaporate through hydrodynamic escape under the strong irradiation of the host star, creating shrouds that absorb the core of the chromospheric resonance lines.
Observing the LMC with APEX: Signatures of large-scale feedback in the molecular clouds of 30 Doradus
Authors: Grishunin K. , Weiss A. , Colombo D. , Chevance M. , Chen C.-H. R. , Güsten R. , Rubio M. , Hunt L. K. , Wyrowski F. , Harrington K. , Menten K. M. , Herrera-Camus R. 
Published: November 2023

Context. Stellar feedback plays a crucial role in star formation and the life cycle of molecular clouds. The intense star formation region 30 Doradus, which is located in the Large Magellanic Cloud (LMC), is a unique target for detailed investigation of stellar feedback owing to the proximity of the hosting galaxy and modern observational capabilities that together allow us to resolve individual molecular clouds – nurseries of star formation.
Aims. We study the impact of large-scale feedback on the molecular gas using the new observational data in the 12CO(3 − 2) line obtained with the APEX telescope.
Methods. Our data cover an unprecedented area of 13.8 sq. deg. of the LMC disc with a spatial resolution of 5 pc and provide an unbiased view of the molecular clouds in the galaxy. Using these data, we located molecular clouds in the disc of the galaxy, estimated their properties, such as the areal number density, relative velocity and separation, width of the line profile, CO line luminosity, size, and virial mass, and compared these properties of the clouds of 30 Doradus with those in the rest of the LMC disc.
Results. We find that, compared with the rest of the observed molecular clouds in the LMC disc, those in 30 Doradus show the highest areal number density; they are spatially more clustered, they move faster with respect to each other, and they feature larger linewidths. In parallel, we do not find statistically significant differences in such properties as the CO line luminosity, size, and virial mass between the clouds of 30 Doradus and the rest of the observed field.
Conclusions. We interpret our results as signatures of gas dispersal and fragmentation due to high-energy large-scale feedback.
Evidence for saturated and disrupted magnetic braking from samples of detached close binaries with M and K dwarfs
Authors: Belloni Diogo , Schreiber Matthias R. , Moe Maxwell , El-Badry Kareem , Shen Ken J. 
Published: November 2023

Context. Recent observations of close detached eclipsing M and K dwarf binaries have provided substantial support for magnetic saturation when stars rotate sufficiently fast, leading to a magnetic braking (MB) torque proportional to the spin of the star.
Aims. We investigated here how strong MB torques need to be to reproduce the observationally inferred relative numbers of white dwarf plus M dwarf post-common-envelope binaries under the assumption of magnetic saturation.
Methods. We carried out binary population simulations with the BSE code adopting empirically derived inter-correlated main-sequence binary distributions as initial binary populations and compared the simulation outcomes with observations.
Results. We found that the dearth of extreme mass ratio binaries in the inter-correlated initial distributions is key to reproduce the large fraction of post-common-envelope binaries hosting low-mass M dwarfs (∼0.1 − 0.2 M⊙). In addition, orbital angular momentum loss rates due to MB should be high for M dwarfs with radiative cores and orders of magnitude smaller for fully convective stars to explain the observed dramatic change of the fraction of short-period binaries at the fully convective boundary.
Conclusions. We conclude that saturated but disrupted, that is, dropping drastically at the fully convective boundary, MB can explain the observations of both close main-sequence binaries containing M and K dwarfs and post-common-envelope binaries. Whether a similar prescription can explain the spin down rates of single stars and of binaries containing more massive stars needs to be tested.
The GAPS programme at TNG
Authors: Carleo I. , Malavolta L. , Desidera S. , Nardiello D. , Wang S. , Turrini D. , Lanza A. F. , Baratella M. , Marzari F. , Benatti S. , Biazzo K. , Bieryla A. , Brahm R. , Bonavita M. , Collins K. A. , Hellier C. , Locci D. , Hobson M. J. , Maggio A. , Mantovan G. , Messina S. , Pinamonti M. , Rodriguez J. E. , Sozzetti A. , Stassun K. , Wang X. Y. , Ziegler C. , Damasso M. , Giacobbe P. , Murgas F. , Parviainen H. , Andreuzzi G. , Barkaoui K. , Berlind P. , Bignamini A. , Borsa F. , Briceño C. , Brogi M. , Cabona L. , Calkins M. L. , Capuzzo-Dolcetta R. , Cecconi M. , Colon K. D. , Cosentino R. , Dragomir D. , Esquerdo G. A. , Henning T. , Ghedina A. , Goeke R. F. , Gratton R. , Horta F. Grau , Gupta A. F. , Jenkins J. M. , Jordán A. , Knapic C. , Latham D. W. , Mireles I. , Law N. , Lorenzi V. , Lund M. B. , Maldonado J. , Mann A. W. , Molinari E. , Pallé E. , Paegert M. , Pedani M. , Quinn S. N. , Scandariato G. , Seager S. , Winn J. N. , Wohler B. , Zingales T. 
Published: November 2023

Context. Different theories have been developed to explain the origins and properties of close-in giant planets, but none of them alone can explain all of the properties of the warm Jupiters (WJs, Porb = 10–200 days). One of the most intriguing characteristics of WJs is that they have a wide range of orbital eccentricities, challenging our understanding of their formation and evolution.
Aims. The investigation of these systems is crucial in order to put constraints on formation and evolution theories. TESS is providing a significant sample of transiting WJs around stars bright enough to allow spectroscopic follow-up studies.
Methods. We carried out a radial velocity (RV) follow-up study of the TESS candidate TOI-4515 b with the high-resolution spectrograph HARPS-N in the context of the GAPS project, the aim of which is to characterize young giant planets, and the TRES and FEROS spectrographs. We then performed a joint analysis of the HARPS-N, TRES, FEROS, and TESS data in order to fully characterize this planetary system.
Results. We find that TOI-4515 b orbits a 1.2 Gyr-old G-star, has an orbital period of Pb = 15.266446 ± 0.000013 days, a mass of Mb = 2.01 ± 0.05 MJ, and a radius of Rb = 1.09 ± 0.04 RJ. We also find an eccentricity of e = 0.46 ± 0.01, placing this planet among the WJs with highly eccentric orbits. As no additional companion has been detected, this high eccentricity might be the consequence of past violent scattering events.
The possible evolution of pitch angles of spiral galaxies
Authors: Reshetnikov V. P. , Marchuk A. A. , Chugunov I. V. , Usachev P. A. , Mosenkov A. V. 
Published: November 2023

Aims. The origin and maintenance of spiral structure in galaxies, the correlation between different types of spiral structure and several proposed mechanisms for their generation, and the evolution of spiral arms of galaxies with time are questions that are still controversial. In this note we study the spiral structure in a sample of distant galaxies in order to infer the evolution of spiral arm characteristics with redshift.
Methods. We considered a sample of 171 face-on spiral galaxies in the Hubble Space Telescope COSMOS (The Cosmic Evolution Survey) field. The galaxies are distributed up to z ≈ 1 with a mean value of 0.44. For all galaxies, we determined the pitch angles of the spiral arms and analysed their dependence on redshift; a total of 359 arms were measured.
Results. Analyses of our measurements combined with the literature data suggest a possible evolution of the pitch angles of spiral galaxies: by the modern epoch the spiral pattern, on average, becomes more tightly wound. This may be a consequence of the general evolution of the structure of galaxies as galaxies become more massive over time and their bulges grow. In addition, the distribution of the cotangent of pitch angle of galaxies indicates the possibility that the dominant mechanism of spiral pattern generation changes over time.
Complete F9 Gene Deletion, Duplication, and Triplication Rearrangements: Implications for Factor IX Expression and Clinical Phenotypes
Authors: Ma YuXin , Li Yang , Sun Jie , Liang Qian , Wu Runhui , Ding Qiulan , Dai Jing 
Published: November 2023

Background Factor IX (FIX) plays a critical role in blood coagulation. Complete deletion of F9 results in severe hemophilia B, whereas the clinical implications of complete F9 duplication and triplication remain understudied.
Objective To investigate the rearrangement mechanisms underlying complete F9 deletion (cases 1 and 2), duplication (cases 3 and 4), and triplication (case 5), and to explore their association with FIX expression levels and clinical impacts.
Methods Plasma FIX levels were detected using antigen and activity assays. CNVplex technology, optical genome mapping, and long-distance polymerase chain reaction were employed to characterize the breakpoints of the chromosomal rearrangements.
Results Cases 1 and 2 exhibited FIX activities below 1%. Case 3 displayed FIX activities within the reference range. However, cases 4 and 5 showed a significant increase in FIX activities. Alu-mediated nonallelic homologous recombination was identified as the cause of F9 deletion in case 1; FoSTeS/MMBIR (Fork Stalling and Template Switching/microhomology-mediated break-induced replication) contributed to both F9 deletion and tandem duplication observed in cases 2 and 3; BIR/MMBIR (break-induced replication/microhomology-mediated break-induced replication) mediated by the same pair of low-copy repeats results in similar duplication–triplication/inversion–duplication (DUP–TRP/INV–DUP) rearrangements in cases 4 and 5, leading to complete F9 duplication and triplication, respectively.
Conclusion Large deletions involving the F9 gene exhibit no apparent pattern, and the extra-hematologic clinical phenotypes require careful analysis of other genes within the deletion. The impact of complete F9 duplication and triplication on FIX expression might depend on the integrity of the F9 upstream sequence and the specific rearrangement mechanisms. Notably, DUP–TRP/INV–DUP rearrangements significantly elevate FIX activity and are closely associated with thrombotic phenotypes.
Role of Cytogenetics and Fluorescence In Situ Hybridization in the Laboratory Workup of Acute Myeloid Leukemias
Authors: Jain Hemani , Shetty Dhanlaxmi 
Published: November 2023

AbstractA new understanding of acute myeloid leukemia as a varied group of unique biologic entity has emerged, as a result of the identification of various chromosomal aberrations and their association with clinical prognosis and diagnosis. Following induction treatment, cytogenetic examination can establish the presence of any residual malignant cells, it's recurrence, clonal evolution if any, or the formation of novel abnormalities. The G-banded karyotype has been the gold standard method for detecting all of these aberrations for years. The capacity to examine the entire genome through karyotype analysis quickly enabled the detection of deletions, duplications, and structural rearrangements across every chromosome, and the more frequent ones were associated with particular aberrant clinical symptoms. Fluorescence in situ hybridization (FISH) is a sensitive technology that aids in differential diagnosis or therapeutic planning and provides rapid results. Furthermore, the combination of cytogenetic and molecular profiling enables a more precise evaluation of disease prognosis, diagnosis, classification, risk stratification, and patient treatment. Interphase FISH analysis, in conjunction with G-banded chromosomal analysis, can be used as a major testing tool for the evaluation of hematological neoplasms. For accurate and consistent descriptions of genomic changes identified by karyotyping and FISH, a specified terminology is necessary. The International System for Human Cytogenomic Nomenclature is the main source and provides instructions for documenting cytogenetic and molecular findings in laboratory reports. This review discusses the two methods, karyotyping and FISH, their advantages and limitations, sample requirements, various FISH probes that are used, nomenclature for results reporting, and the necessary quality control measures.
A Scientometric Analysis of the most Highly Cited Publications on Fracture Research from India: 1989-2022
Authors: Vaishya Raju , Gupta Brij Mohan , Kappi Mallikarjun , Vaish Abhishek 
Published: November 2023

Background
India bears a huge burden of accidents and fractures. This study aimed to study the bibliometric characteristics of India's fracture research output during last three decades. The most highly cited publications (HCPs; with 20 or more citations) on orthopaedic fracture research from India were analyzed on various parameters.

Methodology
The Scopus database was used to identify publications on fractures that originated from India, between 1989 to 2022. The top HCPs were retrieved. A bibliometric and network analysis was used to identify the key players, such as organizations, authors and journals, and important keywords besides identifying their collaborative interactions and visual co-occurrences of significant keywords using VOSviewer and Biblioshiny software.

Results
Of the total 1,048 Indian publications, 126 (10.02%) were HCPs (cited 4,695 times). External funding was received in 1.59%, and international collaboration in 15.08%. The most productive organizations were All India Institute of Medical Sciences (AIIMS), New Delhi, followed by Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, and Pandit Bhagwat Dayal Sharma Post Graduate Institute of Medical Sciences (PGIMS), Rohtak. The most impactful organizations were Maulana Azad Medical College (MAMC), Delhi, followed by the Jawaharlal Institute of Postgraduate Medical Education & Research (JIPMER), Pondicherry, and Sancheti Institute of Orthopaedic Research & Rehabilitation, Pune. The most productive authors were R. Malhotra, M.S. Dhillon, and N.K. Magu, and the most impactful authors were U.K. Meena, A.P. Singh, and P. Sancheti. Delhi was the epic of research, followed by Karnataka, Tamil Nadu, and Chandigarh.

Conclusion
This study provides an insight into the research trends, the most influential contributions, and the performance of Indian organizations and authors. It gives some ideas about the past, present, and future hotspots in research.
Ser252Asn Mutation Introduces a New N-Linked Glycosylation Site and Causes Type IIb Protein C Deficiency
Authors: Zhou Shijie , Wu Xi , Song Ying , Li Lei , Shi Chunli , Lai Zhe , Ding Qiulan , Wu Wenman , Dai Jing , Wang Xuefeng , Lu Yeling 
Published: November 2023

Background Protein C (PC) is a vitamin K-dependent anticoagulant serine protease zymogen which upon activation by the thrombin–thrombomodulin (TM) complex downregulates the coagulation cascade by degrading cofactors Va and VIIIa by limited proteolysis. We identified a thrombosis patient who carried a heterozygous mutation c.881G > A, p.Ser252Asn (S252N) in PROC. This mutation was originally described in a report of novel mutations in patients presenting with defective PC anticoagulant activity in Paris. The research identified PC-S252N (the “Paris” mutation) in a propositus and her family members and highlighted the critical role of Ser252 in the anticoagulation process of activated PC (APC).
Material and Methods We expressed the PC-S252N mutant in mammalian cells and characterized the properties in coagulation assays to decipher the molecular basis of anticoagulant defect of this mutation.
Results We demonstrated that PC-S252N had a diminished ability to TM binding, which resulted in its impaired activation by the thrombin-TM complex. However, APC-S252N exhibited a slightly stronger cleavage capacity for the chromogenic substrate. Meanwhile, the catalytic activity of APC-S252N toward FVa was significantly reduced. Sequence analysis revealed that Ser252 to Asn substitution introduced a new potential N-linked glycosylation site (252NTT254) in the catalytic domain of PC, which adversely affected both the activation process of PC and anticoagulant activity of APC.
Conclusion The new N-glycosylation site (252NTT254) resulting from the mutation of Ser252 to Asn252 in PROC affects the overall structure of the protease, thereby adversely affecting the anticoagulant function of protein C. This modification has a negative impact on both TM-promoted activation of protein C and APC cleavage of FVa, ultimately leading to thrombosis in the patient.
Solitary Fibrous Tumor of the Pleura: Surgical Treatment and Recurrence
Authors: Bove Mary , Natale Giovanni , Messina Gaetana , Tiracorrendo Matteo , Rendina Erino Angelo , Fiorelli Alfonso , D'Andrilli Antonio 
Published: November 2023

Abstract
Background Solitary fibrous tumors of the pleura (SFTPs) are primary pleural tumors originating from the mesenchymal tissue. Surgical treatment was the first choice for management of SFTPs. There were no defined guidelines for the follow-up of these tumors and the postoperative therapy due to the rarity of these tumors.
Methods We conducted a retrospective, multicenter study from two high-volume centers in Italy. Data of patients diagnosed with pleural solitary fibrous tumors between January 2003 and October 2022 were prospectively recorded and retrospectively analyzed. The aim of this study was to identify predictive prognostic factors and the correlation between tumor characteristics and recurrence.
Results In all, 107 patients undergoing R0 surgical resection of pleural solitary fibrous tumor were included in the study. Patients were divided in two groups: benign and malignant. All the patients were treated with surgery with the aim to obtain R0 resection. Lung resection was necessary when the tumor adhered strongly to the lung parenchyma or infiltrated it. Twenty of the 107 patients had tumor recurrence. At a multivariate analysis, histological characteristics (high mitotic index) and maximum standardized uptake values (maxSUV) were related to recurrence. The mean disease-free survival (DFS) was 143.3 ± 6.1 months.
Conclusion In our experience, histological features of malignancy and maxSUV are significantly related to recurrence, which can occur even years after the first diagnosis. Surgical excision with negative surgical margins results in good long-term outcomes. After surgery, a long-term and strict follow-up should be done, in order to detect recurrence early. R0 of the recurrence is associated with long-term survival.
Reframing the narrative of magic wind in Arthur Waley’s translation of Journey to the West: another look at the abridged translation
Authors: Wang Feng , Liu Keqiang , Humblé Philippe 
Published: November 2023

AbstractThis article examines Arthur Waley’s abridged translation of “Journey to the West”, titled “Monkey”, and its influence on magic wind narrativity using narrative theory and (re)framing concepts. The research categorises the narrative significance of the magical wind in the source text and highlights its powers as destruction, transport and transformation. In contrast, these elements seem subdued in “Monkey”. Waley’s reframing employs strategies, such as (I) temporal and spatial reframing; (II) selective appropriation, emphasising stories of pilgrims saving their lands, while overshadowing important cultural and religious aspects of the original; and (III) modifying specific labelling techniques that include references to the magical wind.
The functional differentiation of brain–computer interfaces (BCIs) and its ethical implications
Authors: Sun Xiao-yu , Ye Bin 
Published: November 2023

AbstractThe growth of research and applications of brain–computer interfaces (BCIs) has spurred extensive discussion about their ethical implications. However, most existing research has primarily examined ethical issues related to BCIs from a general perspective, with little attention paid to the specific functions of the technology. This has resulted in a mismatch between governance and ethical issues, due to the lack of differentiation between write-in and read-out BCIs. By providing detailed descriptions of the functions and technical approaches of both write-in and read-out BCIs, we argue that ethical governance of BCIs should follow the principle of precise governance and develop refined governance strategies for different functional types of BCIs.