bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH LINGKUNGAN EKSTERNAL DAN INTERNAL TERHADAP STRATEGI PEMASARAN DAN DAMPAKNYA TERHADAP KINERJA PEMASARAN
Authors: Erdi Hery , SM R Bambang 
Published: November 2023

Penelitian ini bertujuan untuk menggambarkan lingkungan eksternal dan internal, strategi pemasaran dan kinerja pemasaran. Juga, untuk mengetahui pengaruh lingkungan eksternal dan internal terhadap strategi pemasaran dan dampaknya terhadap kinerja pemasaran di industri kelapa sawit di wilayah Sumatera Selatan. Desain penelitian yang digunakan adalah kombinasi deskriptif dan verifikasi. Data yang digunakan adalah data primer yang diperoleh dari kuesioner oleh pejabat yang mewakili masing-masing perusahaan sebanyak 125 perusahaan. Sebagai pelengkap, data sekunder juga digunakan dalam penelitian ini. Metode analisis yang digunakan adalah statistik deskriptif untuk setiap variabel yang menggambarkan data, dan metode pemodelan persamaan struktural (SEM) untuk mengetahui pengaruh dan korelasi signifikansi antar variabel.Hasil penelitian menunjukkan bahwa pengaruh lingkungan eksternal pada strategi pemasaran adalah positif dan signifikan; pengaruh lingkungan eksternal terhadap kinerja pemasaran juga positif dan signifikan; pengaruh strategi pemasaran terhadap kinerja pemasaran adalah positif dan signifikan; dan pengaruh lingkungan internal terhadap kinerja pemasaran adalah positif dan signifikan. Penelitian ini memiliki dua orisinalitas. Pertama, ini bertujuan untuk menjadi tambahan pada dimensi strategi pemasaran. Kedua, studi tentang pengaruh lingkungan internal dan eksternal pada strategi pemasaran serta dampaknya terhadap perusahaan kelapa sawit di Sumatera Selatan belum pernah dilakukan sebelumnya.
Kata kunci: lingkungan eksternal, lingkungan internal, strategi pemasaran, kinerja pemasaran, perkebunan kelapa sawit.
PENGARUH KUALITAS PRODUK, PROMOSI, DAN LOKASI TERHADAP KEPUASAPAN PELANGGAN (STUDI KASUS KOPI JANJI JIWA JILID 35 KOTA TANGERANG)
Authors: Nursaidah Mutia , Bastian Asep Ferry , Sukaesih Imas 
Published: November 2023

Penelitian ini bertujuan untuk mengetahui Pengaruh Kualitas Produk (X1), Promosi (X2), Lokasi (X3) terhadap Kepuasan Konsumen (Y) secara parsial dan simultan pada Kopi Janji Jiwa Jilid 35 Kota Tangerang. Populasi penelitian ini adalah pelanggan Kopi Jnaji Jiwa Jilid 35 Kota Tangerang. Sampel yang diambil sebanyak 100 responden dengan menggunakan teknik Non Probability Sampling. Teknik analisa data yang digunakan adalah Uji Validitas, Uji Reabilitas, Uji Asumsi Klasik, Uji Korelasi Berganda, Uji Regresi Linier Berganda, Uji t, Uji F, serta Uji Koefisien Determinasi dengan menggunakan program SPSS Versi 24. Hasil pengujian hipotesis melalui uji t menunjukkan bahwa kedua variabel yaitu Kualitas Produk dan Lokasi berpengaruh signifikan terhadap Kepuasan Pelanggan, sedangkan variabel Promosi tidak berpengaruh signifikan terhadap Kepuasan Pelanggan. Kemudian uji F menunjukkan bahwa variabel Kualitas Produk, Promosi, dan Lokasi secara simultan berpengaruh signifikan terhadap Kepuasan Pelanggan. Berdasarkan Koefisien Determinasi (R2) menunjukkan hasil dari R Square adalah sebesar 0.684 atau 68,4%. Artinya variabel kualitas produk, promosi, dan lokasi dapat menjelaskan variabel kepuasan pelanggan sebesar 68,4%, sisanya sebesar 31,6% dipengaruhi oleh variabel lain diluar model penelitian ini.
PENGARUH GAYA KEPEMIMPINAN DAN PENGAWASAN TERHADAP KINERJA PEGAWAI DINAS KOPERINDAG KOTA SAWAHLUNTO DENGAN IKLIM KERJA SEBAGAI VARIABEL INTERVENING
Authors: Nugraha Axel Gustino , Heliyani Heliyani 
Published: November 2023

Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh gaya kepemimpinan terhadap iklim kerja pegawai, pengaruh pengawasan terhadap iklim kerja, pengaruh gaya kepemimpinan terhadap kinerja pegawai, pengaruh pengawasan terhadap kinerja pegawai, pengaruh iklim kerja terhadap kinerja pegawai, pengaruh gaya kepemimpinan terhadap kinerja dengan iklim kerja sebagai variabel intervening dan pengaruh pengawasan terhadap kinerja dengan iklim kerja sebagai variabel intervening. Sampel dalam penelitian ini adalah pegawai Dinas Koperindag Kota Sawahlunto yang berjumlah 35 orang. Teknik pengambilan sampel adalah teknik sensus karena jumlah pegawai hanya 35 orang yang mengisi kuesioner. Jenis data yang digunakan data primer, metode pengumpulan data menggunakan kuisioner dengan skala Likert. Uji instrumen penelitian uji validitas dan realibilitas. Teknik analisis data terdiri dari uji deskripsi data, uji asumsi klasik, analisis jalur serta pengujian hipotesis. Hasil penelitian menemukan bahwa gaya kepemimpinan berpengaruh positif dan signifikan terhadap iklim kerja pegawai, pengawasan berpengaruh positif dan signifikan terhadap iklim kerja pegawai, gaya kepemimpinan berpengaruh positif dan signifikan terhadap kinerja pegawai, pengawasan berpengaruh positif dan signifikan terhadap kinerja pegawai, iklim kerja berpengaruh positif dan signifikan terhadap kinerja pegawai, iklim kerja tidak berperan sebagai variabel intervening antara gaya kepemimpinan dan kinerja pegawai dan iklim kerja tidak berperan sebagai variabel intervening antara pengawasan dan kinerja pegawai. Penelitian ini memberikan saran bahwa untuk meningkatkan kinerja pegawai, maka diperlukan gaya kepemimpinan yang membangun, iklim kerja yang lebih kondusif dan peningkatan pengawasan.
PENGARUH KEMAMPUAN KERJA, FASILITAS KERJA DAN KESEIMBANGAN KEHIDUPAN KERJA TERHADAP KINERJA ANGGOTA POLISI SATUAN LALU LINTAS POLRES MERANGIN
Authors: Reno Ade , Almasdi Almasdi 
Published: November 2023

Penelitian ini bertujuan untuk melihat pengaruh (1) Kemampuan kerja terhadap kinerja anggota Satuan Polisi Lalu Lintas Polres Merangin (2) Fasilitas kerja terhadap kinerja anggota Satuan Polisi Lalu Lintas Polres Merangin (3) Keseimbangan kehidupan kerja terhadap Kinerja Anggota Satuan Polisi Lalu Lintas Polres Merangin (4) Kemampuan kerja, fasilitas kerja dan keseimbangan kehidupan kerja berpengaruh secara bersama-sama terhadap kinerja anggota Satuan Polisi Lalu Lintas Polres Merangin.Populasi dalam penelitian ini seluruh Anggota Satuan Polisi Lalu Lintas Polres Merangin sebanyak 40 orang. Teknik Penentuan jumlah sampel yang diambil sebagai responden dengan menggunakan total sampling.Hasil penelitian ini menunjukan bahwa (1) Kemampuan kerja memberikan pengaruh signifikan yang positif terhadap kinerja anggota Satuan Polisi Lalu Lintas Polres Merangin (2) Fasilitas Kerja memberikan pengaruh yang positif terhadap kinerja anggota Satuan Polisi Lalu Lintas Polres Merangin (3) Keseimbangan kehidupan kerja memberikan pengaruh yang positif terhadap Kinerja Anggota Satuan Polisi Lalu Lintas Polres Merangin (4) Pelatihan , Kemampuan kerja dan keseimbangan kehidupan kerja secara bersama-sama berpengaruh positif terhadap kinerja Anggota Satuan Polisi Lalu Lintas Polres Merangin
PENGARUH DISIPLIN KERJA DAN MOTIVASI KERJA TERHADAP KINERJA KARYAWAN PADA DINAS PERPUSTAKAAN DAN ARSIP DAERAH KOTA TANGERANG SELATAN
Authors: PRATAMA ANGGA , Febriana Hadijah 
Published: November 2023

Abstrak
Tujuan penelitian ini adalah untuk mengetahui pengaruh disiplin kerja dan motivasi kerja terhadap kinerja karyawan pada Dinas Perpustakaan dan Arsi Daerah Kota Tangerang Selatan baik secara parsial maupun secara simultan. Metode yang digunakan dalam penelitian ini adalah metode analisis asosiatif dengan pendekatan kuantitatif. Hasil penelitian ini adalah Disiplin kerja berpengaruh signifikan terhadap kinerja karyawan. Motivasi kerja berpengaruh signifikan terhadap kinerja karyawan. Disiplin kerja dan motivasi kerja secara simultan berpengaruh signifikan terhadap kinerja
Kata kunci: Disiplin Kerja; Motivasi Kerja; Kinerja Karyawan
Study of 3D binder-free silicide/silicon anodes for lithium-ion batteries
Authors: Cherf Shiraz , Golodnitsky Diana 
Published: November 2023

Silicon anode materials have attracted much attention as an alternative to the graphite anode in Li-ion batteries since the theoretical capacity of silicon is an order of magnitude higher than that of graphite. However, the drastic volume changes of silicon during lithiation/delithiation cause breakup of the electrode, electrical isolation of the active material and capacity fade. Binders and conducting agents, while improving adhesion and electrical conductivity, reduce the volumetric capacity of the Si anodes. In this article, we present the study of improved, easy-to-fabricate binder-free 3D silicon anodes. The anodes are prepared by combining for the first time three approaches: use of Si nanoparticles, use of porous, high-surface-area metal foam current collector and formation of metal silicide layer in between. The fabrication of 3D anodes includes electrophoretic deposition of silicon nanoparticles (SiNP) on copper, nickel, and titanium foams followed by annealing at different temperatures and time. Analysis of morphology and electrochemical performance of composite 3D silicon/silicide anodes reveals that increased annealing time of SiNPs-deposited on Ni foam results in a thicker Ni3Si2 layer, which leads to the enhanced capacity retention and power capability. At C/10 and C/2 rates the reversible capacity of NMC/3DSi-Ni3Si2 cells was 880 and 530 mAh/gSi+Silicide, respectively.
Intakes of folate, vitamin B6, and vitamin B12 and cardiovascular disease risk: a national population-based cross-sectional study
Authors: Huang Jiamin , Khatun Pipasha , Xiong Yuqing , Liu Bingrui , Zhao Yisu , Lyu Quanjun 
Published: November 2023

BackgroundOnly a few studies that investigated dietary intakes of folate, vitamin B6, and vitamin B12 in relation to cariovascular disease (CVD). This study aimed to assess the association of dietary folate, vitamin B6, and vitamin B12 with CVD in the United States population.MethodsA cross-sectional analysis of 65,322 adults aged ≥ 20 years who participated in the Third National Health and Nutrition Examination Survey (NHANES III) and NHANES 1999–2018. Before 2003, dietary intake data were assessed using a 24-hour dietary call, and two 24-hour dietary calls were used during 2003 and 2018. Odds ratios and 95% confidence intervals (CIs) for CVD associated with dietary folate, vitamin B6, and vitamin B12 were estimated using multivariate logistic regression models.ResultsDietary vitamin B6 intake were inversely associated with the odds of CVD. In males, the multivariable OR for the highest vs. lowest quartiles of vitamin B6 was 0.77 (95%CI: 0.61–0.97, Ptrend = 0.013) for the odds of CVD. In females, the adjusted OR for the highest quartile of vitamin B6 compared with the lowest quartile was 0.73 (95%CI: 0.56–0.95, Ptrend = 0.038) for the odds of CVD. No significant association was observed between dietary folate and vitamin B12 intakes and the odds of CVD.ConclusionsOur findings indicate that higher intake of dietary vitamin B6 may be associated with lower prevalence of CVD, suggesting that dietary vitamin B6 has major public health implications in the prevention of CVD in the United States population.
A longitudinal study of incident hypertension and its determinants in Indian adults aged 45 years and older: evidence from nationally representative WHO-SAGE study (2007–2015)
Authors: Bhatia Mrigesh , Dixit Priyanka , Kumar Manish , Dwivedi Laxmi Kant 
Published: November 2023

ObjectivesHypertension (HT) is a leading cause of mortality and morbidity in developing countries. This study aimed to estimate the incidence of HT among adults aged 45 years and older in India and its associated risk factors.MethodsThis study used longitudinal data from the Indian sample of the first and second waves of the World Health Organization Study on Global Ageing and Adult Health (WHO-SAGE). A bivariate analysis using Pearson's chi-square test was done to examine the associations of individual, lifestyle, and household characteristics with HT status reported in Wave 2. Incident HT changes were analyzed by adjusting for various covariates in the generalized estimating equation (logit link function) with an exchangeable correlation matrix and robust standard errors.ResultsThe study found that during the 8-year period from 2007 to 2015, the incidence of HT in individuals aged 45 years and over was 20.8%. Pre-hypertensive individuals had an overall incidence rate of 31.1 per 1,000 [95% confidence interval (CI): 26.20–35.9] and a 2.24 times higher odds ratio: 2.24 (95% CI: 1.65–3.03) of developing incident HT compared to those who were normotensive. Adults aged 45 years and older, overweight/obese individuals, and women were more at risk of incident HT.ConclusionOne in five individuals had developed HT over 8 years, with a greater risk of incident HT among women than men. Pre-hypertensive individuals were at a greater risk of developing incident HT compared to normotensive individuals. The study recommends comprehensive and effective management of pre-HT to tackle the burden of HT.
Case Report: PROS1 (p.Leu584Arg) pathogenic mutation causes portal and superior mesenteric venous thromboembolism
Authors: Ding Peng , Zhou Yuan , Zhang Kai-Chen , Li Sheng , Long Kun-lan , Chen Jun , Chen Ying-jie , Gao Pei-yang 
Published: November 2023

BackgroundGenetic and acquired risk factors are fundamental to developing venous thromboembolism. Autosomal dominant protein S deficiency caused by pathogenic mutations in the PROS1 gene is a well-known risk factor for thrombophilia.Case presentationWe report a 30-year-old male patient who presented to the hospital with portal vein thrombosis. The patient had a history of abdominal pain for one month. Abdominal vascular CT showed venous thrombosis in the portal vein and superior mesenteric vein. He was diagnosed with “portal and superior mesenteric vein thrombosis, small bowel obstruction and necrosis, acute upper gastrointestinal bleeding (UGIB), hemorrhagic shock.” Serum protein S levels were decreased, and gene sequencing revealed a heterozygous missense mutation in PROS1, c.1571T &gt; G (p.Leu584Arg). The patient received anticoagulation therapy with Enoxaparin Sodium and rivaroxaban, transjugular intrahepatic portosystemic shunt (TIPS), and ICU treatments. Although the patient had a severe bleeding event during anticoagulation therapy, he recovered well after active treatment and dynamic monitoring of anti-Xa.ConclusionHereditary protein S deficiency caused by a mutation in the PROS1 gene is the genetic basis of this patient, and Enoxaparin Sodium and rivaroxaban have been shown to be highly effective.
Effect of hyperlipidemia on the outcome of in vitro fertilization in non-obese patients with polycystic ovary syndrome
Authors: Yang Fang , Lu Jin-Chun , Shen Tao , Jin Yi-Han , Liang Yuan-Jiao 
Published: November 2023

IntroductionIt is little known whether hyperlipidemia alone has adverse effects on the outcome of in vitro fertilization (IVF) in patients with polycystic ovarian syndrome (PCOS).MethodsThe PCOS patients with body mass index (BMI) &lt; 30 kg/m2 were performed IVF or intracytoplasmic sperm injection treatment, including 208 fresh cycles and 127 frozen embryo transfer (FET) cycles. All the patients were divided into hyperlipidemia and control groups, and embryo quality and pregnancy outcomes between the two groups were compared.ResultsIn the fresh cycles, total gonadotropin dosage in the control group was significantly lower than that in the hyperlipidemia group, and serum estradiol levels on trigger day were reversed (P &lt; 0.05). The embryo fragment score was positively correlated with serum low-density lipoprotein level (r = 0.06, P &lt; 0.05) and negatively with serum high-density lipoprotein (HDL) and lipoprotein A levels (r = -0.489 and -0.085, P &lt; 0.01). Logistic regression analysis found that HDL was beneficial for clinical pregnancy (OR = 0.355, 95% CI: 0.135-0.938, P &lt; 0.05). In the FET cycles, there were no differences in pulse index, systolic/diastolic ratio and serum estradiol and progesterone levels between the two groups, but resistance index in the hyperlipidemia group was significantly higher than that in the control group (P &lt; 0.05).ConclusionHyperlipidemia may increase the dosage of gonadotropin and have adverse effect on the embryo quality, endometrial receptivity, and clinical outcomes of lean PCOS patients. It is recommended that the non-obese patients with hyperlipidemia and PCOS perform lipid-lowering treatment before undergoing embryo transfer.
The metabolic repression effect of carbon-ion radiotherapy in synchronous hormone-sensitive oligometastatic prostate cancer
Authors: Zhang Zhenshan , Pei Yulei , Hu Wei , Xue Yushan , Ning Renli , Guo Xiaomao , Sun Yun , Zhang Qing 
Published: November 2023

BackgroundMetastatic prostate cancer (PCa) poses a significant public health concern. While radiation therapy (RT) is commonly utilized in the treatment of synchronous oligometastatic hormone sensitive prostate cancer (OM-HSPC), the occurrence of biochemical recurrence still remains. To deepen our understanding and optimize the outcome of OM-HSPC, we conducted this study to investigate the characteristics of PCa progression and explore potential synergistic mechanisms involving carbon-ion radiotherapy (CIRT) and neoadjuvant androgen deprivation treatment (naADT) in OM-HSPC.MethodsMetabolomic analysis was conducted with 72 urinary samples (at different timepoints) from 33 Patients (T2-3N0M0-1b) and 18 healthy volunteers by using liquid chromatography-tandem mass spectrometry (LC-MS/MS). MetaboAnalyst website and R software were employed for metabolomic analysis and visualization (using the criteria of p value &lt; 0.05 and |FC|&gt;1.5). The impact of CIRT on metabolism were further verified and explored through in vitro and in vivo experiments.ResultsWe found that most metabolites (223 out of 233) were upregulated in treatment-naïve PCa samples compared to healthy samples. After naADT, 60 core risk metabolites were still significantly related to PCa’s progression, and the glutamine level which was significantly higher in OM-HSPC compared to other groups. Remarkably, after CIRT treatment, the glutamine levels in OM-HSPC were significantly reduced to the level of healthy samples. Experiments further confirmed CIRT’s ability to suppress glutamine levels in PCa tumors and its potential enhancement with glutamine deprivation intervention.ConclusionCIRT with naADT might synergistically inhibit HS-OMPC development, progression and even the ADT resistance through glutamine metabolism repression, moreover, the glutamine metabolism might be a novel target to further improved the efficacy of CIRT.
Reversal of mitochondrial permeability transition pore and pancreas degeneration by chloroform fraction of Ocimum gratissimum (L.) leaf extract in type 2 diabetic rat model
Authors: Salemcity A. J. , Olanlokun John Oludele , Olowofolahan A. O. , Olojo F. O. , Adegoke Ayodeji Mathias , Olorunsogo O. O. 
Published: November 2023

Introduction: Unmanaged Diabetes Mellitus (DM) usually results to tissue wastage because of mitochondrial dysfunction. Adverse effects of some drugs used in the management of DM necessitates the search for alternative therapy from plant origin with less or no side effects. Ocimum gratissimum (L.) (OG) has been folklorically used in the management of DM. However, the mechanism used by this plant is not fully understood. This study was designed to investigate the effects of chloroform fraction of OG leaf (CFOG) in the reversal of tissue wastage in DM via inhibition of mitochondrial-mediated cell death in streptozotocin (STZ)-induced diabetic male Wistar rats.Methods: Air-dried OG leaves were extracted with methanol and partitioned successively between n-hexane, chloroform, ethylacetate and methanol to obtain their fractions while CFOG was further used because of its activity. Diabetes was induced in fifteen male Wistar rats, previously fed with high fat diet (28 days), via a single intraperitoneal administration of STZ (35 mg/kg). Diabetes was confirmed after 72 h. Another five fed rats were used as the normal control, treated with corn oil (group 1). The diabetic animals were grouped (n = 5) and treated for 28 days as follows: group 2 (diabetic control: DC) received corn oil (10 mL/kg), groups 3 and 4 were administered 400 mg/kg CFOG and 5 mg/kg glibenclamide, respectively. Body weight and Fasting Blood Glucose (FBG) were determined while Homeostasis Model Assessment of Insulin Resistance (HOMA-IR) and beta cell (HOMA-β), and pancreatic tissue regenerating potential by CFOG were assessed. Activity-guided purification and characterization of the most active principle in CFOG was done using chromatographic and NMR techniques. The animals were sacrificed after 28 days, blood samples were collected and serum was obtained. Liver mitochondria were isolated and mitochondrial permeability transition (mPT) was investigated by spectrophotometry.Results: CFOG reversed diabetic-induced mPT pore opening, inhibited ATPase activity and lipid peroxidation. CFOG reduced HOMA-IR but enhanced HOMA-β and caused regeneration of pancreatic cells relative to DC. Lupanol was a major metabolite of CFOG.Discussion: Normoglycemic effect of CFOG, coupled with reversal of mPT, reduced HOMA-IR and improved HOMA-β showed the probable antidiabetic mechanism and tissue regenerating potentials of OG.
Intraoperative parameters and postoperative follow-up of foam-based intraperitoneal chemotherapy (FBIC)
Authors: Khosrawipour Carolina , Nicpoń Jakub , Kiełbowicz Zdzisław , Prządka Przemysław , Liszka Bartłomiej , Al-Jundi Said , Khosrawipour Veria , Li Shiri , Lau Hien , Kulas Joanna , Diakun Agata , Kielan Wojciech , Chabowski Mariusz , Mikolajczyk-Martinez Agata 
Published: November 2023

Background: For decades, intraperitoneal chemotherapy (IPC) has been delivered into the abdominal cavity as a liquid solution. Recently the concept of foam as a carrier-solution for IPC was suggested. This in-vivo swine study aims to evaluate the safety, intraoperative parameters, limitations and postoperative complications of foam-based intraperitoneal chemotherapy (FBIC).Methods: Three 65-day-old swine received FBIC with doxorubicin in a laparoscopy setting. Intraoperative parameters were monitored throughout the procedure and an extensive postoperative laboratory monitoring was conducted for 7 days. At day seven an autopsy was performed for further evaluation.Results: The insufflation of FBIC caused a temporary rise in blood pressure and a simultaneous drop in heart rate. Capnography detected a continuous increase in end-tital CO2 levels. A temporary drop of intraabdominal temperature was noted. Postoperative blood and serum laboratory results did not indicate any organ failure. No indication of intraperitoneal infections was noted and no structural tissue changes were visible in the autopsy.Discussion: The application of FBIC appears to be a feasible approach regarding intraoperative anesthesiology and postoperative surgical management. A lack of postoperative structural changes on the seventh day were a promising sign of safety and biocompatibility. Surgical reintervention would have been possible. To discuss a possible clinical application, further studies are required to investigate long-term safety, pharmacodynamics and the antitumoral potential of FBIC.