bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical-epidemiological profile of COVID-19 and its relationship with chronic diseases in the state of Pernambuco/Brazil
Authors: Lacerda Vitória Regina Lago , Ferreira Paulo de Oliveira Arnaud , Silva Marcus Vinícius Braga , Pereira Arthur Makoto Ueoka , Lima Leonardo César Soares , Sousa Marco Antonio D'Almeida Gomes dos Santos , Chaves Elem Cristina Rodrigues , Rodrigues Maria Helena Cruz 
Published: November 2023

Objective: To analyze the clinical-epidemiological and laboratory profile of COVID-19 and the relationship with chronic diseases in Pernambuco/Brazil. Methodology: Descriptive and analytical study of the population affected by COVID-19, in Pernambuco, between 08/28-18/11/2020. Results: There was a prevalence of COVID-19 between 31 and 60 years (p<0.0001); with higher records in Health Units (E-SUS) for women (57.58%; p<0.0001) and Emergency Care (F-SUS) for men (51.73%; p<0.0001). Among symptomatic patients in the E-SUS, cough (26.2%), fever (22.3%) and odynophagia (19.4%) prevailed - mild profile (78.5%; p<0.0001); and, in the F-SUS, saturation <95% (36.3%) and dyspnea (28.6%) - severe profile (63.8%; p<0.0001). In clinical evolution, patients under 60 years of age had a favorable outcome in the absence of comorbidities (79.6%; p<0.0001); in those over 60 years of age, the outcome was death among those without comorbidity (61.2%; p0.0083), two comorbidities (72.9%; p0.0001), three or more comorbidities (81.8%; p0.0005) and for cardiovascular diseases (63.6%; p0.0036). Conclusion: It was possible to observe a distinct clinical profile between E-SUS and F-SUS care, and vulnerability in >60 years with or without comorbidity.
Keywords: COVID-19; Comorbidity; Pernambuco
Defense Policy Roadmap Towards a Golden Indonesia 2045: Establishment of the Indonesian Space Armed Forces
Authors: Sarjito Aris 
Published: November 2023

Abstract
The current condition of Indonesia's defense capabilities is a topic of great importance, considering the evolving geopolitical landscape and the increasing need for a strong defense force in the region.
This research aims to examine the rationale behind the establishment of the Indonesian Space Armed Forces as a crucial component of Indonesia's defense policy roadmap towards a golden future by 2045.
This qualitative research will employ a secondary data analysis method. It will draw upon various sources, including government reports, academic papers, and expert opinions, to gather the necessary information for analysis. The research findings will shed light on the current condition of Indonesia's defense capabilities, highlighting strengths and areas that require improvement.
The study will delve into the rational reasons for establishing the Indonesian Space Armed Forces, emphasizing the growing importance of space technology in defense and the need to safeguard Indonesia's interests and sovereignty in space. Furthermore, it will explore the key components of a defense policy roadmap, including advanced defense systems, a robust military-industrial complex, and enhanced regional cooperation.
The research will also assess the implementation of the defense policy roadmap and the challenges hindering its progress. It will examine issues such as budget constraints, technology transfer, human resource development, and strategic partnerships.
In conclusion, this research explores Indonesia's defense capabilities, the establishment of the Indonesian Space Armed Forces, and the challenges faced in implementing a comprehensive defense strategy for a secure future.
Keywords: defense capabilities, defense policy roadmap, golden Indonesia, Indonesian Space Armed Forces
Riimillisen laulun asema pitkällä 1800-luvulla
Authors: Hämäläinen Niina , Karhu Hanna 
Published: November 2023

Tarkastelemme artikkelissa rahvaan parissa suositun riimillisen laulun asemaa sekä arvostuksen puutetta pitkällä 1800-luvulla. Riimillisen kansanlaulun ongelmallisuutta käsitellään sekä kansanrunojen julkaisu- ja keruutoiminnassa että kansallisessa projektissa, jossa tarkoituksena oli ohjata rahvasta siveellisiin tapoihin. Osoitamme, ettäsivistyneistö arvosti riimillisen laulun melodioita, mutta väheksyi laulun sanoituksia ja esitystapaa. Riimillinenlauluperinne oli 1700-luvulla ollut vahvasti sidoksissa ruotsinkielisiin sävelmä- ja käännöslainoihin, ja osa sivistyneistöstä suhtautui riimilliseen lauluun vieraana, ei-suomalaisena. Erilaisia riimillisen laulun julkaisusuunnitelmia kuitenkin esiintyi esimerkiksi Elias Lönnrotilla, H. A. Reinholmilla ja Lauri Soinilla, mutta nämä hankkeet eivät laajamittaisesti toteutuneet. Esitämme, että kattavan riimillistä laulua sisältävän kansanrunokokoelman puute on heikentänyt perinteenlajin arvostusta entisestään. Lisäksi osoitamme, että riimillisen lauluperinteen hahmottamisella vain musiikillisten ominaisuuksiensakautta on pitkät juuret. Riimillistä lauluperinnettä ovatkin tutkineet pääasiassa kansanmusiikintutkijat, vaikka kyseinen lauluperinne oli 1800-luvulla vallitseva rahvaan lyyrisen itseilmaisun muoto. Aineistona käytetään kansanrunokokoelmien esipuheita, kirjeitä, tieteellisiä tekstejä sekä muuta riimilliseen lauluun liittyvää keskustelua aikakaus- ja sanomalehdissä 1810-luvulta 1920-luvulle. Artikkelin näkökulma on reseptiohistoriallinen.
Asiasanat: Suullinen perinne, riimillinen laulu, väheksytty perinne, 1800-luku, arvostus, julkaisut
Suomalaisten unet historian- ja perinteentutkimuksessa
Authors: Kanerva Kirsi , Koski Kaarina , Lamberg Marko 
Published: November 2023

Katsausartikkeli keskittyy unien tutkimuksen asemaan suomalaisen tieteen kentillä. Tarkastelussa painottuu historiatieteessä ja kansanperinteessä tehty tutkimus, mutta katsauksessa nostetaan esiin myös muilla tieteenaloilla tehtyä ja käynnissä olevaa tutkimusta. Myös kansainvälinen konteksti otetaan huomioon. Suomalainen lähdeaineisto mahdollistaa unien tutkimisen alkaen 1400-luvulla kirjatuista unikuvauksista, joita on siellä täällä osana hengellistä kirjallisuutta. Reformaation jälkeen unikuvauksia kirjattiin etenkin oikeuspöytäkirjoihin noituusoikeudenkäyntien yhteydessä, ja juuri noituuskäsityksiäkoskeva tutkimus toi menneisyyden unimaailmat osaksi historiantutkimusta. Sittemmin huomiota ovat saaneet myös unien rooli herätysliikkeissä ja ylipäänsä uskonnollisissa kokemuksissa samoin kuin sotien tuottamat painajaiset. Modernin suomalaisen yhteiskunnan unimaailmaa on toistaiseksi tutkittu enemmän psykologian ja kansanperinteen tutkimuksessa. Kansanperinteessä unikuvauksia on vanhastaan tutkittu laajemmin ja kokonaisvaltaisemmin kuin historiantutkimuksessa. Parhaillaan käynnissä olevaa eri aloilla tehtävää unitutkimusta luonnehtii pyrkimys tieteidenväliseen vuorovaikutukseen,mikä onkin hedelmällisin tapa tulkita niin menneisyyden kuin nykyisyyden unimaailmoja.
Asiasanat: unet, painajaiset, Suomen historia, pitkänaikavälin tutkimus, historiografia, kansanperinne
Kansallisteatteri ja kaksi Berliiniä
Authors: Korsberg Hanna 
Published: November 2023

Käsittelen artikkelissani teatteria osana kylmän sodan kulttuuridiplomatiaa ja Suomen Kansallisteatterin suhdetta jaettuun Berliiniin. Tutkin itäberliiniläisen Berliner Ensemblen Suomen-vierailua syyskuussa 1959 ja Kansallisteatterin vierailua Länsi-Berliiniin lokakuussa 1961, jolloin teatteri esiintyi Berliinin juhlaviikkojen (Berliner Festwoche) ohjelmassa. Berliner Ensemble esitti helsinkiläisyleisölle Mutter Couragen ja Leben des Galilein, joista ensin mainitun pääroolissa nähtiin Helene Weigel. Kansallisteatteri vei juhlaviikoille Eino Kaliman ohjauksen Anton Tšehovin näytelmästä Lokki. Lokin kaksi esitystä Hebbel-teatterissa olivat Kansallisteatterin suurimpia kansainvälisiä menestyksiä. Tarkastelen vierailuja erityisesti suhteessa Seppo Hentilän tulkintaan, jonka mukaan kylmän sodan aikaisista kansainvälisistä kiistakysymyksistä juuri Saksan-kysymys vaikutti eniten Suomen asemaan kahden rintaman välissä. Ainoana Euroopan maana Suomi ei voinut normalisoida suhteitaan kumpaankaan Saksaan. Hentilän mukaan Helsinki oli 1950-luvun alusta alkaen ainoa pääkaupunki, jossa Saksat kilpailivat suomalaisten suosiosta. Tämä näkyi myös teatteritaiteen vierailuissa, sillä ne olivat sekä Suomen että Suomeen kohdistunutta kulttuuridiplomatiaa.
Asiasanat: teatteri, kylmä sota, kulttuuridiplomatia, Kansallisteatteri, Berliner Ensemble
Políticas Públicas Sociales Desde la Propuesta de una Gobernanza Institucional. Una Visión Reflexiva Desde los Gobiernos Autónomos Descentralizados
Authors: Macias-Guerrero Carol Patricia , Melendez Hilarion José Vegas 
Published: November 2023

Objetivo: Armonizar el diseño de las políticas sociales públicas desde la perspectiva de la gobernanza institucional propuesta de los gobiernos autónomos descentralizados.

Métodos: paradigma interpretativo y perspectiva cualitativa. Método inductivo-interpretativo basado en el diseño hermenéutico-descriptivo. Se utilizaron la observación directa y las entrevistas a fondo, con el apoyo de Atlas ti.

Resultados: Los resultados de esta investigación muestran la importancia de la gobernanza como estrategia de gestión pública para la formulación de políticas públicas, especialmente en el caso del desarrollo sostenible.

Conclusión: La estructura de gobernanza institucional existente debe diseñarse dentro de una funcionalidad operativa que logre reunir a los actores sociales de la localidad (provincia) y generar la sinergia necesaria en el desarrollo de políticas sociales públicas locales basadas en una visión de gobernanza.
MEDIA PEMBELAJARAN PEMROGRAMAN DASAR BERBASIS FLASH UNTUK SISWA KELAS X JURUSAN MULTIMEDIA SMK VIP MA”ARIF NU 1 KEMIRI PURWOREJO
Authors: Ar Rasyid Muhammad Habiburrahman , Machmudi Moch Ali , Wahyudiono Sugeng 
Published: November 2023

Penelitian ini bertujuan untuk merancang dan membangun Media Pembelajaran Pemrograman Dasar berbasis Flash sehingga membuat siswa kelas X memahami materi Variabel, Tipe Data dan Operator dengan mudah.Penelitian ini menggunakan pendekatan penelitian dan pengembangan (Research and Development) dengan metode pengembangan sistem Multimedia Development Life Cycle. Pengembangan sistem dengan metode ini dilakukan melalui enam tahapan, yaitu concept, design, material collecting, assembly, testing dan distribution.Hasil penelitian ini adalah sebuah media pembelajaran untuk mata pelajaran pemrograman dasar kelas X dengan materi variabel, tipe data dan operator. Yang diharapkan memudahkan siswa sehingga meningkatkan semangat belajar dan prestasi siswa. Kata Kunci : Media Pembelajaran, Research and Development, MDLC.
Ubóstwo energetyczne w Polsce: analiza skali i zróżnicowania na przykładzie gmin powiatu augustowskiego
Authors: Wendt Jan , Mrozowska Sylwia , Duraj Bartosz , Bógdał-Brzezińska Agnieszka 
Published: November 2023

Konflikt zbrojny pomiędzy Rosją a Ukrainą spowodował znaczne ograniczenie dostaw surowców energetycznych z Rosji do Polski, a ceny energii w Polsce drastycznie wzrosły w drugiej połowie 2022 r. Konieczne wydaje się zatem zbadanie skali ubóstwa energetycznego (EP) w Polsce, aby skutecznie wspierać dotknięte nim gospodarstwa domowe. Ponieważ polityki wsparcia mają sens jedynie na poziomie gmin, celem podjętych przez autorów badań była analiza czynników i określenie zasięgu EP gospodarstw domowych na wybranym obszarze — powiatu augustowskiego. Drugim celem badania jest wykazanie, iż wybór metody badawczej i przyjętych kryteriów może prowadzić do znacząco dużych rozbieżności w wynikach, co może determinować wybór metody badawczej ze względów politycznych i ekonomicznych. W celu weryfikacji hipotezy o większym stopniu EP na wsi niż w gminach miejskich wykorzystano dane na poziomie gmin, w podziale na gminy miejskie i wiejskie. W badaniach wykorzystano obliczenia statystyczne oraz analizę bogatej literatury dotyczącej definicji i teorii pomiaru ubóstwa. Badania wykazały przestrzenne zróżnicowanie EP na terenie badanego powiatu (w którym wynosiło 27,85%) i jego gmin. W mieście Augustów EP wyniosło 11,00%, a w gminie Płaska, charakteryzującej się najwyższym poziomem ubóstwa, sięgało ponad 64,00%. Wybrana metoda badawcza, oparta na ustawowej definicji ubóstwa energetycznego, w istotny sposób ogranicza występowanie tego zjawiska w porównaniu z innymi metodami. W literaturze przedmiotu nie osiągnięto konsensusu co do definicji ubóstwa energetycznego. Doprowadziło to do przyjęcia odmiennych metod i kryteriów badania, co spowodowało istotne różnice w określeniu jego skali, co utrudniało prowadzenie polityki wsparcia gospodarstw domowych.
Epidemiología y características clínico patológico de los linfomas b difuso de células grandes del servicio de hematología atendidos en el Hospital Clínico Viedma en la gestión 2019-2022
Authors: García Cristian , Anze Barrientos Grace , Villegas Navas Ricardo 
Published: November 2023

Objetivo General: Determinar la epidemiologia y características clínico patológicos de pacientes diagnosticados con Linfoma B Difuso de células Grandes atendidos en el servicio de oncohematología gestión 2019-2022. Métodos: Es un estudio Descriptivo, longitudinal prospectiva con enfoque cuantitativo analítico, estudiando 71 pacientes entre las edades mayores de 15 años, diagnosticados de Linfoma no Hodgkin ingresando al estudio 48 pacientes diagnosticados con Linfoma B Difuso de Células Grandes atendidos en el servicio de hematología del Hospital Viedma. Resultados: De acuerdo a rango de edad en la población de estudio es entre 45 a 74 años siendo un 73%, el sexo femenino con una frecuencia del 52%, con el estadio de Ann Arbor III -IV corresponde a 66.7% de la población, las regiones ganglionares comprometidas son > de 3 regiones con 29.2% y presencia de conglomerado ganglionar 35.4%, de la población de estudio el 56.7% realizaron tratamiento de los cuales solo el 31.3% realizo con Rituximab y la respuesta al tratamiento con 61% en pacientes que cumplieron los 6 ciclos de quimioterapia en valor de Spearman existe correlación y significativa (rho Spearman =1, sig=0.003) correlación entre las dos variables. Conclusiones: La incidencia de Linfoma B Difuso de Células Grandes es el 67.6% el diagnóstico realizado por inmunohistoquímica estadificándose al diagnóstico existiendo correlación con respuesta al tratamiento de 61% en los que completaron 6 ciclos, pero no existiendo correlación de datos con marcador para doble expresión BCL-2 y CMY por no ser solicitada en la población de estudio.
Hematocolpos por Tabique transverso vaginal obstructivo: reporte de un caso
Authors: Rojas Mariel Antezana , Rosas Rojas María Rosario 
Published: November 2023

El tabique vaginal transverso es una anomalía obstructiva infrecuente del aparato genital femenino siendo la más frecuente el himen imperforado. El diagnóstico se basa en anamnesis, una exploración física y estudios de imagen. El manejo terapéutico debe realizarse según la extensión del tabique su grosor, localización y clínica de la paciente.
Caso; niña de 14 años con distensión abdominal progresiva, acompañada de dolor en hipogastrio. No había presentado menarca aun, con antecedente post quirúrgico de laparotomía exploradora + exeresis de quiste endometriosico, drenaje de hematocolpos, himenotomia mediante una dilatación con histerometro del tabique, es dada de alta en 17 días. Retorna a servicio a los 3 meses, presentando dolor y distensión abdominal, llegando a diagnosticarse hematotra, tabique transverso, se realiza drenaje y fibrolisis y se procede a colocar un dilatador vaginal con el fin de impedir el cierre, esto hizo posible el exitoso tratamiento con buena evolución y sin recidivas.
Healthcare Monitoring Sensors Based on Organic Transistors: Surface/Interface Strategy and Performance
Authors: Jiang Xingyu , Shi Cheng , Wang Zi , Huang Lizhen , Chi Lifeng 
Published: November 2023

AbstractOrganic transistors possess inherent advantages such as flexibility, biocompatibility, customizable chemical structures, solution‐processability, and amplifying capabilities, making them highly promising for portable healthcare sensor applications. Through convenient and diverse modifications at the material and device surfaces or interfaces, organic transistors allow for a wide range of sensor applications spanning from chemical and biological to physical sensing. In this comprehensive review, the surface and interface engineering aspect associated with four types of typical healthcare sensors is focused. The device operation principles and sensing mechanisms are systematically analyzed and highlighted, and particularly surface/interface functionalization strategies that contribute to the enhancement of sensing performance are focused. An outlook and perspective on the critical issues and challenges in the field of healthcare sensing using organic transistors are provided as well.
Double Gain of Efficient UV‐C Phosphor and Fast Scintillator Based on Pr3+‐doped KY3F10 Nano‐Glass Composites
Authors: Wang Sikai , Hua Chunshuai , Wang Lu , Wang Ci , Liu Lu , Ren Jing , Zhang Jianzhong 
Published: November 2023

AbstractGlassy phosphors offer a promising opportunity to overcome the limits of polycrystalline counterparts, thanks to their merits including excellent optical transparency, abandonment of organic binders, and capability of drawing fibers, etc. However, research and development of glassy UV‐C phosphors and fast scintillators have seriously lagged behind crystals. Here, a new type of efficient UV‐C phosphors and fast scintillators (double gain) is developed from Pr3+‐doped transparent nano‐glass composites (nano‐GCs) containing KY3F10 nanocrystals. Such a material combines favorably the advantages of both crystal and glass, exhibiting intense interconfigurational 5d‐4f emissions of Pr3+ upon deep‐UV, high energy electron‐beam and X‐ray excitations. The emission profile ideally overlaps with the germicidal effectiveness curve. The Pr3+‐doped nano‐GCs are endowed with a radiative decay time shorter than that of extensively studied Ce3+‐doped glasses and nano‐GCs. They exhibit intense X‐ray excited radioluminescence that is comparable to the standard Bi4Ge3O12 (BGO) crystal and significantly stronger than Pr3+‐doped ZBLAN fluoride glass known for the high luminescence efficiency. An X‐ray imaging system with a good spatial resolution using the Pr3+‐doped nano‐GCs is also demonstrated.
Synthesis of Isoquinolinediones via the Radical Addition/Cyclization of N‐Alkyl‐N‐methacryloylbenzamides with Monoalkyl Oxalates
Authors: Xu Jinli , Zhao Chenyue , Cheng Dongping , Xu Xiaoliang 
Published: November 2023

AbstractA photocatalytic reaction of N‐alkyl‐N‐methacryloylbenzamides with monoalkyl oxalates is described. Monoalkyl oxalates undergo single‐electron oxidation/CO2 extrusion to generate alkoxycarbonyl radicals, followed by the addition and subsequent cyclization to give alkoxycarbonyl substituted isoquinolinediones. A wide variety of monoalkyl oxalates were amenable in this protocol, affording various alkoxycarbonyl substituted isoquinolinediones.
Facile Preparation of Carbohydrate‐Containing Adjuvants Based on Self‐Assembling Glycopeptide Conjugates
Authors: Wang Biao , Liu Sijin , Li Haoting , Dong Weidong , Liu Haiyun , Zhang Jun , Tian Chao , Dong Suwei 
Published: November 2023

AbstractCarbohydrates are intriguing biomolecules possessing diverse biological activities, including immune stimulating capability. However, their biomedical applications have been limited by their complex and heterogeneous structures. In this study, we have utilized a self‐assembling glycopeptide conjugate (GPC) system to produce uniform nanoribbons appending homogeneous oligosaccharides with multivalency. This system successfully translates the nontrivial structural differences of oligomannoses into varied binding affinities to C‐type lectin receptors (CLRs). We have shown that GPCs could promote the CLR‐mediated endocytosis of ovalbumin (OVA) antigen, and two mannotriose‐modified peptides F3m2 and F3m5 exhibit potent activity in inducing antigen‐presenting cell maturation, as indicated by increased CD86 and MHCII expression. In vivo studies demonstrated that GPCs, combined with OVA antigen, significantly enhanced OVA‐specific antibody production. Specifically, F3m2 and F3m5 exhibited the highest immunostimulatory effects, eliciting both Th1‐ and Th2‐biased immune responses and promoting differentiation of CD4+ and CD8+ T cells. These findings highlight the potential of GPCs as vaccine adjuvants, and showcase their versatility in exploiting the biological functions of carbohydrates.
AIEgens Cross‐linked Iron Oxide Nanoparticles Synchronously Amplify Bimodal Imaging Signals in Situ by Tumor Acidity‐Mediated Click Reaction
Authors: Dong Yansong , Liu Ye , Tu Yalan , Yuan Youyong , Wang Jun 
Published: November 2023

AbstractActivatable dual‐modal molecular imaging probes present a promising tool for the diagnosis of malignant tumors. However, synchronously enhancing dual‐modal imaging signals under a single stimulus is challenging. Herein, we propose an activatable bimodal probe that integrates aggregation‐induced emission luminogens (AIEgens) and iron oxide nanoparticles (IOs) to synergistically enhance near‐infrared fluorescence (NIRF) intensity and magnetic resonance (MR) contrast through a tumor acidity‐mediated click reaction. Tumor acidity‐responsive IOs containing dibenzocyclooctyne groups (termed cDIOs) and AIEgens containing azide groups (termed AATs) can be covalently cross‐linked in response to tumor acidity, which leads to a simultaneous enhancement in NIRF intensity (≈12.4‐fold) and r2 relaxivity (≈2.8‐fold). cDIOs and AATs were effectively activated in mice orthotropic breast tumor, and the cross‐linking prolonged their retention in tumor, further augmenting the bimodal signals and expanding imaging time frame. This facile strategy leverages the inherent properties of probes themselves and demonstrates promise in future translational studies.
Direct Quantification of Nanoplastics Neurotoxicity by Single‐Vesicle Electrochemistry
Authors: Wei Shiyi , Wu Fei , Liu Jing , Ji Wenliang , He Xiulan , Liu Ran , Yu Ping , Mao Lanqun 
Published: November 2023

AbstractNanoplastics are recently recognized as neurotoxic factors for the nervous systems. However, whether and how they affect vesicle chemistry (i.e., vesicular catecholamine content and exocytosis) remains unclear. This study offers the first direct evidence for the nanoplastics‐induced neurotoxicity by single‐vesicle electrochemistry. We observe the cellular uptake of polystyrene (PS) nanoplastics into model neuronal cells and mouse primary neurons, leading to cell viability loss depending on nanoplastics exposure time and concentration. By using single‐vesicle electrochemistry, we find the reductions in the vesicular catecholamine content, the frequency of stimulated exocytotic spikes, the neurotransmitter release amount of single exocytotic event, and the membrane‐vesicle fusion pore opening‐closing speed. Mechanistic investigations suggest that PS nanoplastics can cause disruption of filamentous actin (F‐actin) assemblies at cytomembrane zones and change the kinetic patterns of vesicle exocytosis. Our finding shapes the first quantitative picture of neurotoxicity induced by high‐concentration nanoplastics exposure at a single‐cell level.
Copper‐Catalyzed Oxygenative Skeletal Rearrangement of Tetrahydro‐β‐carbolines Using H2O and O2 as Oxygen Sources
Authors: Peng Yu‐Sheng , Wang Wei , Shi Jun , Wu Wei , Song Jun‐Rong , Pan Wei‐Dong , Hao Ge‐Fei , Ren Hai 
Published: November 2023

AbstractHerein, we report an unprecedented skeletal rearrangement reaction of tetrahydro‐β‐carbolines enabled by copper‐catalyzed single‐electron oxidative oxygenation, in which H2O and O2 act as oxygen sources to generate a unique 2‐hydroxyl‐3‐peroxide indoline intermediate. The synthetic reactivity of 2‐hydroxyl‐3‐peroxide indoline species was demonstrated by a unique multi‐step bond cleavage and formation cascade. Using a readily available copper catalyst under open‐air conditions, highly important yet synthetically difficult spiro[pyrrolidone‐(3,1‐benzoxazine)] products were obtained in a single operation. The synthetic utility of this methodology is demonstrated by the efficient synthesis of the natural products donaxanine and chimonamidine, as well as the 3‐hydroxyl‐pyrroloindoline scaffold, in just one or two steps.