bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nanobdellota phyl. nov
.
Authors: Kato Shingo , Itoh Takashi , Ohkuma Moriya 
Published: October 2023

Abstract

Na.no.bdel.lo'ta. N.L. fem. n.
Nanobdella
, the type genus of the phylum; N.L. suff. ‐
ota
, ending to denote a phylum; N.L. neut. pl. n.
Nanobdellota
, the phylum
Nanobdella
.

The phylum “
Nanoarchaeota
” was proposed in 2002 to accommodate the sole species “
Nanoarchaeum equitans
,” which is symbiotically associated with a host archaeon
Ignicoccus hospitalis
. Since then, several members of the phylum “
Nanoarchaeota
” have been cultivated with their hosts and described. However, until the publication of
Nanobdella aerobiophila
in 2022, no species or genus within the phylum “
Nanoarchaeota
” had their names validly published in accordance with the International Code of Nomenclature of Prokaryotes (ICNP). Meanwhile, it was decided recently that the rank of phylum should be included in the current version of ICNP. Therefore, we herein propose the phylum name
Nanobdellota
phyl. nov. with
Nanobdella
as the type genus to enable valid publication of the phylum name.
Nanobdellota
contains the class
Nanobdellia
, whose name is also validly published. Cultivated members of this phylum are obligately symbiotic, only growing in coculture with their specific hosts. Depending on their hosts, they grow under aerobic or anaerobic conditions. Cells are small cocci and occur singly or attached to the cell surface of their hosts. The genome size of the members of this phylum range between 0.49 and 0.67 Mb.

DNA G + C content (mol%)
: 24.2–32.2.

Type genus
:
Nanobdella
Kato et al. 2022
VP
.
Advances in Gene Mapping Studies in Tree Nut Crops
Authors: Marrano Annarita , Arab Mohammad M. , Bernard Anthony , Pierro Erica A. Di 
Published: October 2023

Abstract
Nut tree species have a great economic and cultural value for many countries across the world. Their highly nutritious content makes them one of the most favourite healthy foods of the global population, with strong evidence of their positive impact on human health. Nut tree crops are very diverse in terms of nut chemical content and shape, growing climates, and domestication history. However, all of them have a very long juvenile phase that makes classical breeding challenging and time consuming. Also, their cultivation is very resource demanding. The application of genomic‐assisted breeding can accelerate the development of adaptive cultivars of nut tree species. In this article, we summarize recent successes in genomics for nut tree crops, specifically almond, chestnut, hazelnut, pecan, pistachio, and walnut. We report the recent discoveries on the genetic control of target traits for the genetic improvement of these species, with suggestions for future directions and breeding applications.
Nerve pathology of microangiopathy and thromboinflammation in hereditary transthyretin amyloidosis
Authors: Yeh Shin‐Joe , Yeh Ti‐Yen , Wang Yi‐Shiang , Chao Chi‐Chao , Tzeng Shiou‐Ru , Tang Tsz‐Yi , Hsieh Jung‐Hsien , Kan Yu‐Yu , Yang Wei‐Kang , Hsieh Sung‐Tsang 
Published: October 2023

AbstractObjectiveDespite amyloid deposition as a hallmark of hereditary transthyretin amyloidosis (ATTRv) with polyneuropathy, this pathology could not completely account for nerve degeneration. ATTRv patients frequently have vasomotor symptoms, but microangiopathy hypothesis in ATTRv was not systemically clarified.MethodsThis study examined the vascular pathology of sural nerves in ATTRv patients with transthyretin (TTR) mutation of p.Ala117Ser (TTR‐A97S), focusing on morphometry and patterns of molecular expression in relation to nerve degeneration. We further applied human microvascular endothelial cell (HMEC‐1) culture to examine the direct effect of TTR‐A97S protein on endothelial cells.ResultsIn ATTRv nerves, there was characteristic microangiopathy compared to controls: increased vessel wall thickness and decreased luminal area; both were correlated with the reduction of myelinated fiber density. Among the components of vascular wall, the area of collagen IV in ATTRv nerves was larger than that of controls. This finding was validated in a cell model of HMEC‐1 culture in which the expression of collagen IV was upregulated after exposure to TTR‐A97S. Apoptosis contributed to the endothelial cell degeneration of microvasculatures in ATTRv endoneurium. ATTRv showed prothrombotic status with intravascular fibrin deposition, which was correlated with (1) increased tissue factor and coagulation factor XIIIA and (2) reduced tissue plasminogen activator. This cascade led to intravascular thrombin deposition, which was colocalized with upregulated p‐selectin and thrombomodulin, accompanied by complement deposition and macrophages infiltration, indicating thromboinflammation in ATTRv.InterpretationMicroangiopathy with thromboinflammation is characteristic of advanced‐stage ATTRv nerves, which provides an add‐on mechanism and therapeutic target for nerve degeneration.
Enzyme‐Engineered Metal‐Organic Frameworks for the Construction of Organophosphorus Pesticide Biosensor
Authors: Li Hongxia , Lu Qi , Shi Junxiao , Zhang Xiaoguang , Sun Peng , Yan Xu , Lu Geyu 
Published: October 2023

AbstractRational immobilization of fragile enzymes on a scaffold is an efficient protocol to achieve robust biocatalyst, yet the construction remains challenging due to the trade‐off between enzyme activity and framework environment. Herein, an enzyme‐engineered assembly strategy enabling the in situ fusion of acetylcholinesterase (AChE) into Zn‐based metal‐organic frameworks (Zn‐MOF‐74) during the rapid nucleation and crystal defect growth process, is demonstrated. The Zn‐MOF‐74 composites can offer a hydrophilic framework microenvironment for maintaining the biological state of AChE, with flower‐like porous structure that allows for boosting the mass transfer process of substrates and products. Impressively, the apparent activity of AChE can be well maintained 90% after encapsulation, and the AChE@Zn‐MOF‐74 composites produced excellent stability in inhospitable environments. Given the structural integration, a robust AChE@Zn‐MOF‐74‐based biosensor is constructed for the sensitive detection of chlorpyrifos (organophosphorus pesticides) with a detection limit of 1.0 ng mL−1, enabling the monitoring of pesticide degradation extent in the water body. This study is anticipated to offer valuable insight into understanding the structure‐activity relationship of enzyme@MOF to encourage applications in the construction of robust biosensors for precision agriculture.
Lignin‐Based Encapsulation of Liquid Metal Particles for Flexible and High‐Efficiently Recyclable Electronics
Authors: Zheng Yong , Liu Hai , Yan Li , Yang Haiyue , Dai Lin , Si Chuanling 
Published: October 2023

AbstractRoom‐temperature liquid metals (RTLMs) have excellent shape reconfiguration capabilities, which make them ideal for flexible electrodes, sensors, and energy devices. However, due to the high surface tension and weak adhesion of RTLM, the types of printing substrates, patterning, and recovery processes are limited. It is essential to develop advanced encapsulation techniques for the patterning of RTLMs. Lignin has great potential for promotion as nanodispersants and nanocarriers because of its abundant hydroxyl groups and good self‐assembly properties. In this work, a green and facile encapsulation method using industrial lignin is reported for stable, uniform, and reproducible patterning of eutectic gallium–indium (EGaIn). Lignin‐encapsulated EGaIn particles exhibit good stability and can be patterned on the surface of various substrates with a simple ballpoint pen. The electrical resistance of the conductive tracks shows little change under bending and twisting (720°) conditions. More importantly, the lignin‐encapsulated system can be easily dissolved and regenerated, which is also supported by molecular dynamics simulations and density functional theory calculations. 96.9% of the EGaIn can be recovered from the system. These characteristics make it very environmentally friendly throughout the preparation process and find applications in flexible sensors, transient circuits, and many other areas.
Oxygen‐Generating Hydrogels as Oxygenation Therapy for Accelerated Chronic Wound Healing
Authors: Yang Zhixuan , Ren Kaixuan , Chen Yehao , Quanji Xinyan , Cai Chengfeng , Yin Jingbo 
Published: October 2023

AbstractHypoxia in chronic wounds impairs the activities of reparative cells, resulting in tissue necrosis, bacterial infections, decreased angiogenesis, and delayed wound healing. To achieve effective oxygenation therapy and restore oxygen homeostasis, oxygen‐generating hydrogels based on different oxygen sources have been developed to release dissolved oxygen in the wound bed, which not only alleviate hypoxia, but also accelerate chronic wound healing. This review first discusses the vital role of oxygen and hypoxia in the wound healing process. The advancements in oxygen‐generating hydrogels, which produce oxygen through the decomposition of hydrogen peroxide, metal peroxides, glucose‐activated cascade reactions, and photosynthesis of algae microorganisms for chronic wound healing, are discussed and summarized. The therapeutic effects and challenges of using oxygen‐generating hydrogels for the clinical treatment of chronic wounds are concluded and prospected.
Advanced Synthetic Scaffolds Based on 1D Inorganic Micro‐/Nanomaterials for Bone Regeneration
Authors: Zhang Yonggang , Zhu Yingjie , Habibovic Pamela , Wang Huanan 
Published: October 2023

AbstractInorganic nanoparticulate biomaterials, such as calcium phosphate and bioglass particles, with chemical compositions similar to that of the inorganic component of natural bone, and hence having excellent biocompatibility and bioactivity, are widely used for the fabrication of synthetic bone graft substitutes. Growing evidence suggests that structurally anisotropic, or 1D inorganic micro‐/nanobiomaterials are superior to inorganic nanoparticulate biomaterials in the context of mechanical reinforcement and construction of self‐supporting 3D network structures. Therefore, in the past decades, efforts have been devoted to developing advanced synthetic scaffolds for bone regeneration using 1D micro‐/nanobiomaterials as building blocks. These scaffolds feature extraordinary physical and biological properties, such as enhanced mechanical properties, super elasticity, multiscale hierarchical architecture, extracellular matrix‐like fibrous microstructure, and desirable biocompatibility and bioactivity, etc. In this review, an overview of recent progress in the development of advanced scaffolds for bone regeneration is provided based on 1D inorganic micro‐/nanobiomaterials with a focus on their structural design, mechanical properties, and bioactivity. The promising perspectives for future research directions are also highlighted.
Air‐Working Electrochromic Artificial Muscles
Authors: Ling Yong , Li Linpeng , Liu Junhao , Li Kerui , Hou Chengyi , Zhang Qinghong , Li Yaogang , Wang Hongzhi 
Published: October 2023

AbstractArtificial muscles are indispensable components for next‐generation robotics to mimic the sophisticated movements of living systems and provide higher output energies when compared with real muscles. However, artificial muscles actuated by electrochemical ion injection have problems with single actuation properties and difficulties in stable operation in air. Here, air‐working electrochromic artificial muscles (EAMs) with both color‐changing and actuation functions are reported, which are constructed based on vanadium pentoxide nanowires and carbon tube yarn. Each EAM can generate a contractile stroke of ≈12% during stable operation in the air with multiple color changes (yellow‐green‐gray) under ±4 V actuation voltages. The reflectance contrast is as high as 51%, demonstrating the excellent versatility of the EAMs. In addition, a torroidal EAM arrangement with fast response and high resilience is constructed. The EAM's contractile stroke can be displayed through visual color changes, which provides new ideas for future artificial muscle applications in soft robots and artificial limbs.
Polarization and Spectrum Multi‐Dimensional Sensitive Perovskite Photodetectors
Authors: Guo Linqi , Sun Haoxuan , Wang Meng , Min Liangliang , Zhou Yicheng , Cao Fengren , Li Liang 
Published: October 2023

AbstractWithout optical and mechanical components, resolving information from composite light is challenging even from two dimensions. 3D (intensity, spectrum, and polarization state) reconstruction is extremely rare and only explored in the infrared region. Herein, the first polarization‐ and spectrum‐sensitive photodetector in the visible region is constructed, which relies on orientations of perovskite nanowire arrays and in situ voltage modulation. This detector can realize real‐time detection of spectral information and Stokes vector simultaneously. Such a design successfully obtains the information from three dimensions, and the multi‐dimensional imaging capability has also been demonstrated. This work provides a valid instance of multi‐dimensional photodetection and shows a development direction of extracting target features from miscellaneous information.
BHE‐YOLO: Effective Small Target Detector for Aluminum Surface Defect Detection
Authors: Xu Jianjun , Hu Xiangtao , Zhang Yongle , Li Ziyi 
Published: October 2023

AbstractAluminum surface defect detection is a critical task to make location and classification predictions about defects in the industrial production process. However, defects complexity and the requirement of rapid production have led to a great challenge for existing detection algorithms. In this work, an effective small target detector named BHE‐YOLO is proposed for aluminum surface defect detection. First, the BiFPN is modified and integrated with YOLOv5s to achieve effective weighted feature fusion and cross‐scale connection. Second, the Hard Swish activation function is applied to better extract defect feature information. Third, the Equalized Focal Loss function is introduced to replace the cross‐entropy formula of the negative sample confidence part of the loss function. Finally, the experiments are carried out on the aluminum profile defect dataset of the Aliyun Tianchi Competition. The results demonstrate that BHE‐YOLO has excellent performance in terms of Precision, Recall, F1 score, and mAP, and its superiority over the typical detection algorithms, especially for small target defects of aluminum surface.
Microneedle‐Mediated Cell Therapy
Authors: Gao Ziqi , Sheng Tao , Zhang Wentao , Feng Huiheng , Yu Jicheng , Gu Zhen , Zhang Yuqi 
Published: October 2023

AbstractMicroneedles have emerged as a promising platform for transdermal drug delivery with prominent advantages, such as enhanced permeability, mitigated pain, and improved patient adherence. While microneedles have primarily been employed for delivering small molecules, nucleic acids, peptides, and proteins, recent researches have demonstrated their prospect in combination with cell therapy. Cell therapy involving administration or transplantation of living cells (e.g. T cells, stem cells, and pancreatic cells) has gained significant attention in preclinical and clinical applications for various disease treatments. However, the effectiveness of systemic cell delivery may be restricted in localized conditions like solid tumors and skin disorders due to limited penetration and accumulation into the lesions. In this perspective, an overview of recent advances in microneedle‐assisted cell delivery for immunotherapy, tissue regeneration, and hormone modulation, with respect to their mechanical property, cell loading capacity, as well as viability and bioactivity of the loaded cells is provided. Potential challenges and future perspectives with microneedle‐mediated cell therapy are also discussed.
Cellular and molecular characteristics of the premetastatic niches
Authors: Liu Hongfei , Zhang Guoxin , Gao Ran 
Published: October 2023

AbstractThe premetastatic niches (PMN) formed by primary tumor‐derived molecules regulate distant organs and tissues to further favor tumor colonization. Targeted PMN therapy may prevent tumor metastasis in the early stages, which is becoming increasingly important. At present, there is a lack of in‐depth understanding of the cellular and molecular characteristics of the PMN. Here, we summarize current research advances on the cellular and molecular characteristics of the PMN. We emphasize that PMN intervention is a potential therapeutic strategy for early prevention of tumor metastasis, which provides a promising basis for future research and clinical application.
Construction of double cross‐linked networks in calcium alginate/poly‐N‐isopropylacrylamide hydrogel with photothermal responsiveness for absorbing heavy metal ions
Authors: Wang Jinheng , Zhao Zhonghua , Wang Jikui , Guo Weihong 
Published: October 2023

AbstractHydrogels have been widely used for adsorbing heavy metal ions in wastewater treatment. Herein, a calcium alginate/poly‐N‐isopropylacrylamide double‐network hydrogel with photothermal responsiveness was prepared for adsorbing heavy metal ions in aqueous solution. The chemical composition, micromorphology, swelling properties, photothermal responsiveness, adsorption properties, and adsorption mechanism of gel microspheres were studied, respectively. The gel microspheres had an interpenetrating three‐dimensional porous structure, and their high porosity morphology and high specific surface area could ensure the adequate exposure of active adsorption sites. The gel microspheres showed excellent selective adsorption of Cr(III), and the theoretical maximum adsorption capacity of 146.16 mg/g was calculated according to the Langmuir model. Besides, its excellent photothermal conversion ability enhanced the resistance to external interference after the adsorption. Our work has provided an innovative approach to solar water purification while optimizing the preparation process.
Microwave absorption performance of nitrile butadiene rubber/ethylene propylene diene monomer rubber filled with multiwalled carbon nanotubes
Authors: Kang Le , Qu Jinlei , Liu Yilin , Zhang Baogang , Qu Yongtao 
Published: October 2023

AbstractIn recent times, there is an increasing need for effective control of electromagnetic pollution, which can avoid excessive radiation effects on the human body. Microwave absorption materials are attracting wide research interests to reduce electromagnetic pollution due to the rapid development of electronic equipment. In this study, Nitrile butadiene rubber (NBR)/ethylene propylene diene monomer rubber (EPDM) were mixed with multiwalled carbon nanotubes (MWCNT) to prepare microwave absorbing materials. The distribution of fillers, AC conductivity, complex permittivity, and microwave absorption performance of the composites were systematically investigated. It found that the AC conductivity, both real and imaginary parts of the permittivity were significantly improved in the composite with the increasing ratio of MWCNT contents. The NBR/EPDM/MWCNT composites with eight parts per hundred concerning with rubber (phr) MWCNT had a minimum reflection loss (RLmin) of −48.1 dB at the optimum thickness of 2.07 mm. Importantly, the adding sequence of MWCNT and plasticizer dioctyl phthalate (DOP) to the rubber matrix is found to play an important role in determining the distribution of fillers and the structure of polymer blends. The composite with plasticizer added before MWCNT exhibited a better impedance matching and as a result, achieved a good microwave absorption performance.
Implications of Inflammatory Processes on a Developing Central Nervous System in Childhood‐Onset Systemic Lupus Erythematosus
Authors: van der Heijden Hanne , Rameh Vanessa , Golden Emma , Ronen Itamar , Sundel Robert P. , Knight Andrea , Chang Joyce C. , Upadhyay Jaymin 
Published: October 2023

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that is increasingly affecting pediatric and adult populations. Neuropsychiatric manifestations (ie, cognitive dysfunction and mood disorders) appear to occur with greater severity and poorer prognosis in childhood‐onset SLE (cSLE) versus adult‐onset SLE, negatively impacting school function, self‐management, and psychosocial health, as well as lifelong health‐related quality of life. In this review, we describe pathogenic mechanisms active in cSLE, such as maladaptive inflammatory processes and ischemia, which are hypothesized to underpin central phenotypes in patients with cSLE, and the role of alterations in protective central nervous system (CNS) barriers (ie, the blood–brain barrier) are also discussed. Recent findings derived from novel neuroimaging approaches are highlighted because the methods employed in these studies hold potential for identifying CNS abnormalities that would otherwise remain undetected with conventional multiple resonance imaging studies (eg, T2‐weighted or fluid‐attenuated inversion recovery sequences). Furthermore, we propose that a more robust presentation of neuropsychiatric symptoms in cSLE is in part due to the harmful impact of a chronic inflammatory insult on a developing CNS. Although the immature status of the CNS may leave patients with cSLE more vulnerable to harboring neuropsychiatric manifestations, the same property may represent a greater urgency to reverse the maladaptive effects associated with a proneuroinflammatory state, provided that effective diagnostic tools and treatment strategies are available. Finally, considering the crosstalk among the CNS and other organ systems affected in cSLE, we postulate that a finer understanding of this interconnectivity and its role in the clinical presentation in cSLE is warranted.image
A good name is rather to be chosen: The impact of CEO reputation incentives on corporate green innovation
Authors: Sun Xiaonan , Cifuentes‐Faura Javier , Xiao Yao , Liu Xiaoqian 
Published: October 2023

AbstractIn contrast to studies examining the effects of government incentives such as environmental regulation on corporate green innovation, this paper investigates the influence of CEO reputation, a market‐based incentive mechanism, on companies' green innovation behavior. Utilizing green patent data from Chinese A‐share listed companies from 2007 to 2020, we construct a CEO reputation index through principal component analysis and examine its impact on corporate green innovation behavior and underlying mechanisms. Our findings indicate that CEO reputation positively affects companies' green innovation behavior. This effect is primarily driven by reducing financing constraints, CEOs' risk perception, and rising environmental awareness. Further heterogeneity analysis reveals the positive relationship between CEO reputation and green innovation behavior is more pronounced in companies with strong executive compensation incentives, political connections, and effective internal control.