bluuebunny/crossref_metadata_2025_split huggingface dataset:
Meta‐analysis on the efficacy of Traditional Chinese Medicine in enhancing surgical site wound healing post‐colorectal surgery
Authors: Liu Han‐song , Qian Haihua , Liu Jiali , Zhang Dan 
Published: November 2023

AbstractThis meta‐analysis aimed to evaluate the efficacy of Traditional Chinese Medicine (TCM) in enhancing surgical site wound healing following colorectal surgery. We systematically reviewed and analysed randomized controlled trials (RCTs) that investigated the outcomes of TCM interventions in postoperative wound management, adhering to the PRISMA guidelines. The primary outcome was the assessment of wound healing through the REEDA (redness, oedema, ecchymosis, discharge and approximation) scale at two different time points: the 10th day and 1‐month post‐surgery. Seven RCTs involving 1884 patients were included. The meta‐analysis revealed a statistically significant improvement in wound healing in the TCM‐treated groups compared to the control groups at both time intervals. On the 10th day post‐surgery, the TCM groups exhibited a significant reduction in REEDA scale scores (I2 = 98%; random: SMD: −2.25, 95% CI: −3.52 to −0.98, p < 0.01). A similar trend was observed 1‐month post‐surgery, with the TCM groups showing a substantial decrease in REEDA scale scores (I2 = 98%; random: SMD: ‐3.39, 95% CI: −4.77 to −2.01, p < 0.01). Despite the promising results, the majority of the included studies were of suboptimal quality, indicating a need for further high‐quality RCTs to substantiate the findings. The results suggest that TCM interventions can potentially enhance wound healing post‐colorectal surgery, paving the way for further research in this area to validate the efficacy of TCM in postoperative management.
The effect of affiliation with a large business group on trade credit finance: An empirical analysis of chaebol firms in Korea
Authors: Chong Byung Uk , Im Hyun Joong 
Published: November 2023

AbstractWe investigate the effect of affiliation with a large business group on a firm's trade credit policy while controlling for the effects of its financial health and bargaining power in the Korean setting. Group affiliation may influence trade credit finance through the internal capital market mechanism and/or the extra bargaining power mechanism. In our empirical analyses, we focus on identifying the more dominant mechanism for determining trade credit demand (TCD) and supply (TCS). First, we provide a set of empirical findings showing that a firm's affiliation with a large business group increases the firm's TCD but decreases its TCS. These findings support the extra bargaining power mechanism argument. Second, we provide another set of empirical findings that group‐wise financial distress has weak positive impacts on a group affiliate's TCD and TCS. These findings support the internal capital market mechanism argument. Overall, we provide evidence that large business groups in Korea function uniquely in that the extra bargaining power mechanism greatly dominates the internal capital market mechanism when determining a group affiliate's trade credit transactions. We also provide evidence of the internal capital market mechanism functioning when an entire business group faces severe financial difficulties.
Autologous adipose tissue injection in the treatment of alopecia: A mini‐review
Authors: Sadeghi Sara , Ghane Yekta , Hajizadeh Nima , Goodarzi Azadeh 
Published: November 2023

AbstractBackgroundAlopecia may decrease patients' quality of life and self‐confidence by limiting their social life. Therefore, the main goal of the treatment is to limit or halt the progression of inflammation, scarring, and hair loss. The promising effect of fat injection on hair regrowth, limited adverse effects, and subsiding inflammation can be proof of its efficacy and safety in treating alopecia.AimsThis review sought to assess the role of autologous fat tissue injection in scarring and non‐scarring alopecia.MethodsAccordingly, a thorough search was performed on the Web of Science, Scopus, and PubMed/Medline databases, as well as the Google Scholar search engine, for studies published from inception until September 1st, 2023, using the related keywords.ResultsAutologous fat grafting (AFG) is a novel and potentially effective modality for treating alopecia, particularly primary and secondary cicatricial alopecia. AFG can be an effective semi‐invasive option for treating refractory lichen planopilaris because it induces angiogenesis, which supports hair regrowth. In addition to cicatricial alopecia, AFG held promise for treating non‐scarring alopecia, including androgenic alopecia and alopecia areata. The adipose‐derived regenerative cells (ADRCs) in adipose tissue (AT) secrete different growth factors, further supporting hair regeneration. Moreover, different anti‐inflammatory and anti‐oxidative agents are known in AT, preventing further damage to hair follicles.ConclusionsAFG can significantly control inflammatory processes, improve signs and symptoms, and increase hair density and diameter.
Influence of denture brushing on the surface properties and color stability of CAD‐CAM, thermoformed, and conventionally fabricated denture base resins
Authors: Fouda Shaimaa M. , Gad Mohammed M. , Ellakany Passent , El Zayat Mai , Farooqi Faraz A. , Akhtar Sultan , Salah El‐Din Mai 
Published: November 2023

AbstractPurposeTo assess the influence of denture brushing on the surface roughness, hardness, and color stability of conventional, thermoformed, and CAD‐CAM denture base materials.Materials and MethodsSeven different denture base materials were included in this study; conventional heat‐polymerized acrylic resin (PMMA) served as control, polyamide, acetal, two categories of milled acrylic discs (AvaDent and IvoCad), and two categories of 3D‐printed resins (NextDent and FormLabs). The specimens were constructed according to manufacturers’ instructions and then subjected to simulated brushing (20,000 cycles). According to the brushing method, the specimens were split into three groups, no brushing, brushing with water, and brushing with toothpaste. Surface roughness, hardness, and color change were evaluated before and after brushing. Collected data were analyzed using ANOVA, and post‐hoc Tukey's tests (α = 0.05).ResultsA significant difference was noted between the surface roughness of the tested materials before and after denture brushing (p < 0.05), and milled resin showed the least Ra values. Denture brushing with water significantly increased the Ra of PMMA (p = 0.004) and IvoCad (p = 0.032), while brushing using toothpaste did not show a significant increase. The brushing protocols did not alter the hardness of tested materials except that of PMMA (p = 0.001). The color stability of the tested materials showed comparable results with both brushing protocols.ConclusionThe tested properties showed variations between the types of denture base resins. Hardness and color stability of CAD‐CAM and thermoformed denture base resins were not altered by denture brushing and showed comparable results with both brushing methods. Surface roughness was the only property that showed alteration after denture brushing.
Smelling an odor present during PMR does not impact heart rate during a stressful cognitive task
Authors: Mahmut Mehmet K. , Classen Carl‐Philipp , Croy Ilona , Hummel Thomas 
Published: November 2023

AbstractPrevious research on the impact of odors on current emotional state has been mixed, with some studies finding odors can induce feelings of relaxation while others have not. The aim of Part 1 of the current study was to investigate whether a feeling of relaxation, measured by a self‐report positive and negative affect scale and heart rate (HR), could be associated with an odor after completing three supervised sessions of progressive muscle relaxation (PMR) training while wearing an odorized nasal clip. Although the Part 1 results revealed no differences in positive or negative affect or HR between participants who wore an odorized or non‐odorized nasal clip, the PMR training was effective in reducing HR and negative affect overall. The aim of Part 2 was to determine whether the PMR training sessions in Part 1, could help reduce an objective measure of stress (i.e., HR) during four conditions of a cognitively stressful task, with and without an odorized nasal clip. The results for Part 2 revealed there were no differences in HR between participants who trained with odorized or non‐odorized nasal clips in any of the four conditions. However, given no explicit tests of learned odor‐PMR associations were performed, the lack of group differences may be due to various reasons, including a reduction in any learned association before testing Part 2. In summary and contrary to the hypothesis, participants who completed PMR training with an odorized nasal clip did not demonstrate a lower HR during a stressful cognitive task while wearing the odorized nasal clip, compared to those who wore a non‐odorized nasal clip during PMR training. Future research on the association between odors and relaxation may benefit from adapting the training protocol to include more frequent or longer associations between the behavior and the odor.Practical ApplicationThe findings provide preliminary evidence that wearing an odorized nasal clip during light activities such as progressive muscle relaxation is tolerated well but further research exploring whether this pairing leads to feelings of relaxation when odors are presented alone is warranted.
Novel pharmacological developments in the management of paediatric inflammatory bowel disease: Time for guideline update – A narrative review
Authors: Lee Rachel BY , Gasparetto Marco 
Published: November 2023

AimThe incidence of paediatric inflammatory bowel disease (IBD) continues to increase in both adults and children across the globe, with more than one third of the patients not responding to anti‐tumour necrosis factor biologics and immune modulators. This narrative review provides an overview of novel pharmacological developments in the management of paediatric IBD, including new biological therapies.MethodsA PubMed Medline search was performed to include randomised controlled trials, retrospective and prospective observational studies, and relevant case reports of children with IBD published between 2018 and January 2023. Guidelines and protocols from relevant paediatric and adult gastroenterology societies, such as the European Society for Paediatric Gastroenterology, Hepatology and Nutrition and the European Crohn's and Colitis Organisation, were also included. Non‐pharmacological treatments including therapeutic diets and faecal microbiota transplantation were outside the scope of this work.ResultsEarly real‐world evidence suggests that newer biologics and small molecules, such as anti‐integrins, interleukin‐12 and/or interleukin‐23 inhibitors, Janus kinase and signal transducer and activator of transcription proteins inhibitors, are safe and effective in adult patients with IBD, with promising growing evidence for paediatric IBD.ConclusionWhile many developments have been achieved with novel pharmacological treatments to manage IBD, ongoing research is required to confirm their effectiveness and safety in the paediatric age. Extending the licence of novel treatments to children will be crucial to tackle the increasing loss of response to conventional treatments. International guidelines will require timely updating to incorporate novel treatments within the existing protocols.
Pseudomonas syringae coffee blight is associated with the horizontal transfer of plasmid‐encoded type III effectors
Authors: McTavish Kathryn J. , Almeida Renan N. D. , Tersigni Jonathan , Raimundi Melina K. , Gong Yunchen , Wang Pauline W. , Gontijo Guilherme F. , de Souza Ricardo M. , de Resende Mario L. V. , Desveaux Darrell , Guttman David S. 
Published: November 2023

Summary
The emergence of new pathogens is an ongoing threat to human health and agriculture. While zoonotic spillovers received considerable attention, the emergence of crop diseases is less well studied. Here, we identify genomic factors associated with the emergence of Pseudomonas syringae bacterial blight of coffee.
Fifty‐three P. syringae strains from diseased Brazilian coffee plants were sequenced. Comparative and evolutionary analyses were used to identify loci associated with coffee blight. Growth and symptomology assays were performed to validate the findings.
Coffee isolates clustered in three lineages, including primary phylogroups PG3 and PG4, and secondary phylogroup PG11. Genome‐wide association study of the primary PG strains identified 37 loci, including five effectors, most of which were encoded on a plasmid unique to the PG3 and PG4 coffee strains. Evolutionary analyses support the emergence of coffee blight in PG4 when the coffee‐associated plasmid and associated effectors derived from a divergent plasmid carried by strains associated with other hosts. This plasmid was only recently transferred into PG3. Natural diversity and CRISPR‐Cas9 plasmid curing were used to show that strains with the coffee‐associated plasmid grow to higher densities and cause more severe disease symptoms in coffee.
This work identifies possible evolutionary mechanisms underlying the emergence of a new lineage of coffee pathogens.
A comparison of maxillary posterior changes following facemask therapy: Skeletal anchorage versus tooth‐borne anchorage
Authors: Lee Hyeon‐Jong , Jeong Hannah , Park Jae Hyun , Choi Dong‐Soon , Jang Insan , Cha Bong‐Kuen 
Published: November 2023

AbstractObjectiveTo compare changes in the maxillary posterior structure as seen in cone‐beam computed tomography (CBCT) images resulting from facemask therapy using skeletal (miniplate/FM) anchorage versus tooth‐borne anchorage (RME/FM).Materials and MethodsA retrospective study was conducted on 20 patients divided into the miniplate/FM group (nine patients aged 9.5 ± 1.4 years) and the RME/FM group (11 patients aged 9.2 ± 1.4 years). CBCT images before and after facemask therapy were evaluated to assess changes in the maxillary posterior structure.ResultsThe miniplate/FM group had greater advancement of the maxilla and midface compared to the RME/FM group (p < .05). Specifically, there was about three times more advancement of the pterygomaxillary suture in the miniplate/FM group than in the RME/FM group (p < .05). Moreover, the advancement of the pterygomaxillary suture was about half the advancement of A point in the miniplate/FM group, while only about 25% in the RME/FM group. Finally, the miniplate/FM group showed an increase in the transverse dimension of the posterior and superior parts of the maxilla (p < .05).ConclusionThere was greater forward movement of the pterygomaxillary suture with facemask therapy using the skeletal anchorage compared to tooth‐borne anchorage, leading to a more significant advancement of the maxilla and midface.
Pediatric influenza vaccination in the perioperative setting: A quality improvement project
Authors: Meyer Andrew J. , Smith Jill R. , Wright Tara L. , Engler Laurie J. , Bigham Michael T. , Bhalla Tarun 
Published: November 2023

AbstractIntroduction/BackgroundUnmet need for seasonal influenza vaccination administration to pediatric patients exists at national and local levels. Vaccination during the perioperative period remains controversial, though opportunity exists to meet vaccination need through perioperative programs. The initial SMART Aim of this quality improvement initiative was to establish and increase seasonal influenza vaccination rate in eligible patients during in person preoperative clinic visits in a pediatric perioperative surgical home (PSH) to 10%. Informed by each prior season's experience, we increased our SMART Aim target for vaccinations in seasons two and three to 15 and 18%, respectively.MethodsFollowing the Model for Improvement methodology, the PSH team developed and implemented a perioperative pediatric influenza vaccination program. Across three influenza seasons, key interventions included updates to organizational perioperative vaccination policy, obtaining material influenza vaccination supplies, development of EHR tools, PSH staff education, and communication with patient–families. Rate of eligible patients receiving influenza vaccination at their PSH clinic appointment was tracked over time. Influenza vaccination rates were reported monthly during Season 1, then weekly during seasons two and three. The balancing measure was same day surgery case cancellations related to influenza vaccination given at PSH clinic appointment. Statistical analysis methods utilized include Shewart's control chart and statistical process control (SPC) standards. Special cause variation was determined by eight or more consecutive data points above or below the centerline.ResultsThe influenza vaccination rates in each of the three influenza seasons exceeded vaccination rate goals of 10, 15, and 18%, respectively. A total of 695 vaccines have been administered since program inception. No same day surgical case cancellations were observed as balancing measure.ConclusionsOver three consecutive influenza vaccination seasons, we safely established and met vaccination rate goals of 10, 15, and 18% to eligible patients during preoperative clinic visits within a pediatric PSH system. Through iterative PDSA cycles, we continue to identify opportunities for future improvement. This suggests that the perioperative period presents opportunity for seasonal influenza vaccination with potential program expansion to include routine vaccines of childhood.
Incidence of subsequent surgical decompression following minimally invasive approaches to treat lumbar spinal stenosis: A retrospective review
Authors: Shahzad Hania , Hussain Nasir , D'Souza Ryan S. , Bhatti Nazihah , Orhurhu Vwaire , Abdel‐Rasoul Mahmoud , Simopoulos Thomas , Essandoh Michael K. , Khan Safdar N. , Weaver Tristan 
Published: November 2023

AbstractBackground ContextSurgical decompression is the definitive treatment for managing symptomatic lumbar spinal stenosis; however, select patients are poor surgical candidates. Consequently, minimally invasive procedures have gained popularity, but there exists the potential for failure of therapy necessitating eventual surgical decompression.PurposeTo evaluate the incidence and characteristics of patients who require surgical decompression following minimally invasive procedures to treat lumbar spinal stenosis.Study Design/SettingRetrospective review.Patient SamplePatients who underwent minimally invasive procedures for lumbar spinal stenosis (Percutaneous Image‐guided Lumbar Decompression [PILD] or interspinous spacer device [ISD]) and progressed to subsequent surgical decompression within 5 years.Outcome MeasuresThe primary outcome was the rate of surgical decompression within 5 years following the minimally invasive approach. Secondary outcomes included demographic and comorbid factors associated with increased odds of requiring subsequent surgery.MethodsPatient data were collected using the PearlDiver‐Mariner database. The rate of subsequent decompression was described as a percentage while univariable and multivariable regression analysis was used for the analysis of predictors.ResultsA total of 5278 patients were included, of which 3222 (61.04%) underwent PILD, 1959 (37.12%) underwent ISD placement, and 97 (1.84%) had claims for both procedures. Overall, the incidence of subsequent surgical decompression within 5 years was 6.56% (346 of 5278 patients). Variables associated with a significantly greater odds ratio (OR) [95% confidence interval (CI)] of requiring subsequent surgical decompression included male gender and a prior history of surgical decompression by 1.42 ([1.14, 1.77], p = 0.002) and 2.10 times ([1.39, 3.17], p < 0.001), respectively. In contrast, age 65 years and above, a diagnosis of obesity, and a Charlson Comorbidity Index score of three or greater were associated with a significantly reduced OR [95% CI] by 0.64 ([0.50, 0.81], p < 0.001), 0.62 ([0.48, 0.81], p < 0.001), and 0.71 times ([0.56, 0.91], p = 0.007), respectively.ConclusionsMinimally invasive procedures may provide an additional option to treat symptomatic lumbar spinal stenosis in patients who are poor surgical candidates or who do not desire open decompression; however, there still exists a subset of patients who will require subsequent surgical decompression. Factors such as gender and prior surgical decompression increase the likelihood of subsequent surgery, while older age, obesity, and a higher Charlson Comorbidity Index score reduce it. These findings aid in selecting suitable surgical candidates for better outcomes in the elderly population with lumbar spinal stenosis.
Hydrological niche regulation induced by different resistance strategies facilitates coexistence of P. longipes and L. communis under drought stress
Authors: Yao Kai , Zhang Aoli , Rang Bo , Yang Junting , Liu Yingliang , Wu Yanyou 
Published: November 2023

AbstractUnder global warming, the availability of water resources is one of the most important factors affecting trait evolution and plant species distribution across terrestrial ecosystems, and the relationships between drought resistance strategies and the hydrological niche characteristics of plants are worth studying. We continuously monitored physiological drought response parameters such as gs, Tr, proline, soluble sugar, gene expression and activities of SOD, POD, and CAT to assess drought resistance strategies of Platycarya longipes and Lindera communis; determined plant soil hydrological niche separation by stable H and O isotope analysis; and analysed the effects of interspecific water competition by comparing the differences in morphological and physiological parameters between solo and mixed planting. Under drought stress, L. communis exhibited a drought avoidance strategy, and P. longipes exhibited a drought tolerance strategy. L. communis utilized the water within the shallow soil layer, while P. longipes mainly utilized the water in the deeper soil layer; there were fewer parameters with significant differences between the solo planting and the mixed planting of L. communis compared to P. longipes. Overall, P. longipes benefited from coexistence with L. communis under drought stress, which may be because L. communis employs a drought avoidance strategy, reducing soil water consumption in the drought environment. These results suggested that differences in functional traits or resistance strategies among species benefit species' coexistence in a community under drought stress.
Clinical applicability of external and internal body dimensions in predicting dystocia in late‐gestation Holstein‐Friesian heifers
Authors: Nogalski Zenon , Piwczyński Dariusz , Nogalska Anna 
Published: November 2023

AbstractThe objective of this study was to determine the clinical applicability of maternal intrapelvic area (PA) and selected morphometric parameters that can be measured before parturition in predicting dystocia in dairy heifers. The measurements were performed in 374 late‐gestation Holstein‐Friesian heifers. Inner pelvic height and width were measured using a pelvimeter, and PA was calculated. The heifers were monitored continuously around the time of calving, and calving difficulty was categorized as: unassisted calving (UC), slight assistance (SA), considerable difficulty (CD) and veterinary assistance (VA). Calving performance was analysed with the χ2 test, and the effect of body dimensions on the course of parturition was evaluated by one‐way analysis of variance. Dystocia (CD + VA) was predicted with the use of the classification tree method. Dystocia accounted for 29.14% of all deliveries. The percentages of stillbirths and retained placenta increased (p < .01) with increasing calving difficulty. Average PA immediately before parturition was smaller (p < .01) in group VA (223.2 cm2) than in group UC (253.3 cm2). According to the classification tree, dystocia may occur (74.07% odds) in heifers with PA < 254.2 cm2 and a rump angle <5.68° before parturition. Measurements of heifer's cannon circumference and sire's body size improve the accuracy of dystocia prediction.