bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Fermentasi Madu (Apis Mellifera) Terhadap Gambaran Histologi Ginjal Tikus yang Diinduksi Cisplatin dan Tinjauannya Menurut Pandangan Islam
Authors: Octaviaini Permana Elza Rakhma , Hadi Restu Syamsul , Arifandi Firman 
Published: November 2023

Pendahuluan : Pengobatan kanker yang paling efektif dan yang paling sering digunakan adalah kemoterapi dengan cisplatin. Cisplatin bekerja secara sistemik, sehingga bukan hanya sel kanker saja yang dikenai, tetapi sel-sel sekitarnya yang sehat juga terkena efek sampingnya sehingga penggunaan obat ini harus dibatasi. Perlu adanya solusi yang dapat mengurangi efek samping cisplatin. Bahan alam yang dapat menurunkan efek samping cisplatin adalah fermentasi madu. Metodologi : Penelitian ini menggunakan data primer dengan rancangan eksperimental posttest onlycontrol group design secara in vivo. Penelitian ini memiliki 4 kelompok percobaan yaitu, kelompok kontrol tanpa perlakuan, kelompok cisplatin, kelompok perlakuan fermentasi madu 5% dan paparan cisplatin, serta kelompok perlakuan fermentasi madu 10% dan paparan cisplatin. Setelah itu dilakukan pewarnaan HE dan dilakukan pengamatan secara deksriptif dan kuantitaif. Hasil : Fermentasi madu dapat memberikan efek perubahan ukuran glomerulus, tubulus distal, dan tubulus proksimal mencapai normal. Simpulan : Pemberian fermentasi madu dapat bersifat nefroprotektif dari efek samping cisplatin. Dalam pandangan Islam madu adalah kebesaran Allah yang telah disebutkan di dalam Al-Quran yang dinamai dengan Surah An-Nahl (Lebah).
Incidence Rate and Risk Factors for Diarrhea in Yarsi Medical Faculty Students Batch 2019
Authors: Eryando Izzatul , Irmawati Ike , Istiwara Endy Muhammad 
Published: November 2023

Introduction: Diarrhea is a bowel movement with a mushy or liquid consistency, which can even be water only with a frequency more often than usual (usually three or more times) in one day (Depkes RI 2011). The prevalence of diarrhea in Indonesia according to its characteristics based on the 2018 Riskesdas recorded 18,225 (9%) children with diarrhea aged <1 year, 73,188 (11.5%) children with diarrhea aged 1-4 years, 182,338 (6.2%) children with diarrhea aged 5-14 years, and 165,644 (6.7%) children with diarrhea aged 15-24 years (Ministry of Health, 2019). Diarrhea can occur due to factors such as open defecation, hand washing without soap, food and beverage management, waste safety, and liquid waste safety.Methodology: This study is a correlational study with a cross sectional design. The study population was YARSI medical students. The sampling technique was purposive sampling. The total sample was 166 students.Results: In student respondents, the results showed that the incidence rate of diarrhea in medical students of Yarsi in the last 3 months was quite high because the majority had diarrhea. It is also known that several risk factors studied have a relationship with the incidence rate of diarrhea, namely hand washing behavior and also the source of water drunk. Meanwhile, the level of knowledge, gender, and location of food purchases are not related to the incidence of diarrhea in students.Conclusion: The results of the study found the prevalence of diarrhea and several risk factors associated with the incidence of diarrhea.
Overview of Antibiotic Sensitivity Patterns in Diabetic Ulcers at Gatot Soebroto Army Hospital and Fatmawati General Hospital and The Review According to Islamic Perspective
Authors: Idhalhijah Sherly , Eliana Fatimah , Gunawan Andri 
Published: November 2023

Backgorund : One of the complications of DM is diabetic ulcers which occur due to reduced pain sensation due to neuropathy. Diabetic ulcers are a state of finding infection, destruction to the deepest skin tissue in the feet in patients with diabetes mellitus (DM) due to nerve abnormalities and peripheral arterial vascular disorders, so an overview of the pattern of antibiotics is very important in overcoming the severity of ulcers that can expand.Methodolgy : This research used secondary data from medical records on the antibiotic sensitivity of diabetic foot ulcer patients at the Gatot Subroto Army Hospital and Fatmawati General Hospital from January 2018 to December 2021.Results : There are ten types of antibiotics that sensitive to diabetic foot ulcer patients at Gatot Soebroto Army Hospital, including tigecycline, cefepime, piperacillin tazobactam, amikacin, aztreonam, ceftazidime, ciprofloxacin, gentamicin, meropenem, and ceftriaxone. While the types of antibiotics at Fatmawati General Hospital, include amikacin, piperacillin tazobactam, imipenem, meropenem, ertapenem, gentamicin, trimethophrim sulfamethoxazole, tigecycline, fosfomycin, and cefepime.Conclusion : Sensitive antibiotics in the two hospitals include tigecycline, cefepime, piperacillin tazobactam, amikacin, gentamicin and meropenem. In the view of Islam treatment is a form of effort to seek healing, after which surrender everything to Allah SWT.Keywords : Antibiotic, diabetic ulcer, Army hospital, Fatmawati
Health Conditions of Elderly (Secondary Data Analysis of 2021 Social-Economic Survey Data)
Authors: Maheswari Anindya Puspita , Rifqatussa'adah Rifqatussa'adah , Jannah Fathul 
Published: November 2023

In Indonesia during 2019, the elder population reached 13,4% and is predicted to increase gradually from year to year. In general, the elderly age group is a phase in which most individuals have already got a decrement in health condition, both physically and psychologically. The purpose of this study is to give an overview about the health condition of the elderly. This research method is quantitative using descriptive research type. The research design used in this study is a cross-sectional research design. The sampling method for this study is purposive sampling. The population under this study are SUSENAS 2021 Indonesia with a sample of 18.352 resident within the category of elder age group in Indonesia. The research instrument for this paper is the questionnaire result from SUSENAS 2021. The instrument in this study was the results of the 2021 SUSENAS questionnaire. The result of this study shows that 67,4% of elder age group citizens in Indonesia are within the scope of healthy condition. The result of this research test shows that the health condition of the elder age group is affected by age (p=0,000), education (p=0,000), employment (p=0,000), marital status (p=0,000), social activity (p=0,000), health facility services (p=0,000),community activities (p=0,000), and the environmental factor (p=0,000). Meanwhile, gender did not find a related signicant. The conclusion of this study is that in Islam, the elderly have a high position in society, in particular, from the point of view that they are a source of knowledge and experience, as well as information and thoughts. therefore, they must be respected, loved, cared for and given priority to their health, it is essential that they be harmed, neglected, aware of their health, and given proper attention.
Evaluasi Pelaksanaan Pengumpulan Data Antropometri Di Posyandu Kota Bogor
Authors: Putri Desica Destya , Jalal Fasli , Arifandi Firman 
Published: November 2023

Latar Belakang. Posyandu adalah pelayanan kesehatan yang dilaksanakan disuatu wilayah puskesmas. Banyaknya kader posyandu dengan kemampuan yang kurang hanya mampu menimbang berat badan dan mengisi buku penimbangan. Penelitian ini dilakukan untuk mengevaluasi pengetahuan serta pelaksanaan pengukuruan pada kader posyandu di Kota Bogor. Metode. Metode yang digunakan yaitu evaluasi kualitatif rancangan cross-sectional dengan menggunakan kuesioner yang diberikan pada masing – masing kader di 10 posyandu di Kota bogor. Hasil. Dari 48 kader posyandu didapatkan 60,4% atau 29 kader memiliki pengetahuan kurang Simpulan. Berdasarkan hasil uji korelasi Chi Square, didapatkan tidak adanya hubungan antara pengetahuan dengan usia dan lama menjadi kader namun terdapat hubungan antara pengetahuan dengan banyaknya pelatihan kader
Association between Respiratory Commorbidity and Covid-19 Mortality in Pasir Jaya Village, Cikupa District
Authors: Zulkarnain Hafizhah zaihan , Batubara Lilian 
Published: November 2023

Introduction : The COVID-19 pandemic in Indonesia started in March 2020 and there continues to be a constant increase in the number of cases and deaths due to COVID-19. Comorbid comorbidities (illnesses) experienced by patients at the start of treatment can increase the risk of death due to COVID-19 infection. Various foreign studies have shown that an elderly population with comorbidities has a higher risk of mortality compared to a population without comorbid diseases. Based on a study conducted on the link between lower respiratory tract comorbidities and mortality, the authors wanted to know the relationship between lower respiratory tract comorbidities and mortality in Pasir Jaya village, Cikupa district, Tangerang district.Method : This type of research is a descriptive observational study using a cross-sectional method. The sample in this study were 36 respondents who were COVID-19 patients in Pasir Jaya Village who had experienced COVID-19. Data was collected by conducting direct interviews with respondents. Bivariate analysis was performed using the Chi-Square statistical test.Result : : From the results of the analysis conducted, there were 88.9% of respondents who had comorbid respiratory tract died, 11.1% of respondents who had comorbid respiratory tract improved without symptoms, 11.1% of respondents who did not have comorbid lower respiratory tract improved with symptoms and 88.9% of respondents who did not have comorbidities improved without symptoms. on the chi-square test there is a value of 0.00. The results of the Chi-Square test obtained a p-value of 0.00 (<0.05), thus it can be interpreted that there is a relationship between respiratory comorbidities and COVID-19 mortality.Conclusion : There is significant association between respiratory comorbidities and COVID-19 mortality.
Pengaruh Pandemi Covid-19 terhadap Status Psikologis Pasien Infertilitas di Rumah Sakit Kepresidenan RSPAD Gatot Soebroto
Authors: Andrila Anggi Putri , Mirfat Mirfat 
Published: November 2023

Abstrak Pendahuluan: Pengaruh pandemi COVID-19 berdampak besar pada kehidupan masyarakat, tidak hanya pada kesehatan fisik, namun juga pada kondisi psikologis masyarakat. Dampak psikologis yang terjadi dapat berupa stress, kecemasan, depresi bahkan infertilitas. Infertilitas adalah masalah kesehatan global yang mempengaruhi jutaan orang usia reproduksi di seluruh dunia. Infertilitas juga dikaitkan dengan tekanan psikologis yang sangat besar karena ketidakmampuannya untuk mencapai peran sosial yang diinginkan. Metodologi: Jenis penelitian ini adalah penelitian analitik dengan penelitian survei non-eksperimental. Sampel dalam penelitian ini adalah pasien infertilitas. Teknik pengambilan sampel menggunakan teknik purposive sampling. Teknik pengumpulan data menggunakan data primer dengan alat bantu kuesioner yang disebar dalam bentuk google form. Data dianalisis secara univariat dan bivariat dan teknik analisis data yang digunakan adalah analisis statistik dengan menggunakan Statistical Package for Social Sciences (SPSS) v.26 (IBM Inc) dengan T-test dan Mann-Whitney testHasil: Hasil penelitian ini menunjukan bahwa dampak psikologis (menggunakan skala IES-R) pada pasien infertilitas di RS Kepresidenan RSPAD Gatot Soebroto sebagian besar normal sebanyak 50 responden (52,1%). skala STAI untuk untuk tingkat kecemasan sebanyak 89 responden (92,7%) dan skala VAS sebanyak 62 reponden (64,6%).Kesimpulan: Hasil penelitian ini menunjukkan bahwa adanya pengaruh yang signifikan pada tingkat kecemasan pasien infertilitas dengan riwayat keluarga, kolega teman atau kenalan terinfeksi COVID-19 di RS Kepresidenan RSPAD Gatot Soebroto dengan nilai p value skor VAS 0,038 (p value 0,05). KATA KUNCI Pandemi COVID-19, Psikologis Pasien, Infertilitas
Evaluation of Posyandu Management in Bogor City
Authors: Amelia Fitri , Jalal Fasli , Arifandi Firman 
Published: November 2023

Background: Posyandu is a form of Community-Based Health Efforts (UKBM) carried out by, from and with the community, to empower and provide facilities for the community to obtain health services for mothers, babies and toddlers. Management of health services is an activity or an art to manage health workers and non-health workers to improve public health through health programs. Maq??id al-Sh?ri' are the purposes desired by the legislator (Allah; al-Sh?ri') by establishing a rule of law. Purpose: The purpose of this study was to determine the posyandu management in Bogor City.Methods: this study used a simple random sampling method, namely by selecting two areas of Bogor City with different levels of urban progress, then proceed with the random selection of sub-districts from each area, then the selection of 10 posyandu and cadres randomly without regard to strata in the population . Results: From the 10 posyandu samples, the results of the input component were obtained with a value range of 80-95%, the results of the process component with a value of 100%, the results of the output component with a value range of 50-59% and the results of the SKDN indicator 71-94%.Conclusion: Of the ten Posyandu in Bogor City, the Tegallega Sub-District and the Cikaret Sub-district are good Posyandu.
THE CORRELATION BETWEEN KNOWLEDGE AND BEHAVIOR WITH THE PRESENCE OF HOUSE DUST MITES IN STUDENT BOARDING ROOMS IN EAST CEMPAKA PUTIH AND THE REVIEW OF ISLAMIC PERSPECTIVE
Authors: Putra Hafiz Primadhya , Damayanti Ndaru Andri , Arsyad Muhammad 
Published: November 2023

Introduction: House dust mites (HDM) are the most common allergen found in homes and spread worldwide. The factors that cause TDR life are behaviour and habits that rarely clean the bedroom. Currently, many students still need knowledge and behaviour regarding clean living. This study aims to determine the presence of house dust mites in student boarding rooms and their relationship with students' knowledge and behaviour towards house dust mites. Methods: This research method is quantitative with a cross-sectional approach. This type of research is descriptive correlation research. The population and sample of this study were 50 students in boarding settlements in Cempaka Putih Timur Village, Cempaka Putih District, Central Jakarta. The sample used the Quota Sampling technique. The data collection instrument used a questionnaire. The testing method used is the validity and reliability test using the SPSS application. Data analysis techniques using univariate and bivariate analysis. Results: The results showed that the number of rooms with positive house dust mite presence was less than those with negative house dust mite presence. Than, mattress dust has a higher density of house dust mites. Most students had a good level of knowledge and positive behaviour. Conclusion: There is no significant corelation between knowledge and behaviour with the presence of house dust mites in boarding rooms students. In Islam, a Muslim must have extensive knowledge and good behaviour. Good Muslims will keep themselves and their environment clean so that they are away from sources of disease, including house dust mites.
Molecular epidemiology and antimicrobial resistance patterns of carbapenem-resistant Acinetobacter baumannii isolates from patients admitted at ICUs of a teaching hospital in Zunyi, China
Authors: Xiong Lin , Deng Chengmin , Yang Guangwu , Shen Meijing , Chen Benhai , Tian Rengui , Zha He , Wu Kaifeng 
Published: December 2023

BackgroundCarbapenem-resistant Acinetobacter baumannii (CRAB) has emerged as a predominant strain of healthcare-associated infections worldwide, particularly in intensive care units (ICUs). Therefore, it is imperative to study the molecular epidemiology of CRAB in the ICUs using multiple molecular typing methods to lay the foundation for the development of infection prevention and control strategies. This study aimed to determine the antimicrobial susceptibility profile, the molecular epidemiology and conduct homology analysis on CRAB strains isolated from ICUs.MethodsThe sensitivity to various antimicrobials was determined using the minimum inhibitory concentration (MIC) method, Kirby-Bauer disk diffusion (KBDD), and E-test assays. Resistance genes were identified by polymerase chain reaction (PCR). Molecular typing was performed using multilocus sequence typing (MLST) and multiple-locus variable-number tandem repeat analysis (MLVA).ResultsAmong the 79 isolates collected, they exhibited high resistance to various antimicrobials but showed low resistance to levofloxacin, trimethoprim-sulfamethoxazole, and tetracyclines. Notably, all isolates of A. baumannii were identified as multidrug-resistant A. baumannii (MDR-AB). The blaOXA-51-like, adeJ, and adeG genes were all detected, while the detection rates of blaOXA-23-like (97.5%), adeB (93.67%), blaADC (93.67%), qacEΔ1-sul1 (84.81%) were higher; most of the Ambler class A and class B genes were not detected. MLST analysis on the 79 isolates identified five sequence types (STs), which belonged to group 3 clonal complexes 369. ST1145Ox was the most frequently observed ST with a count of 56 out of 79 isolates (70.89%). MLST analysis for non-sensitive tigecycline isolates, which were revealed ST1145Ox and ST1417Ox as well. By using the MLVA assay, the 79 isolates could be grouped into a total of 64 distinct MTs with eleven clusters identified in them. Minimum spanning tree analysis defined seven different MLVA complexes (MCs) labeled MC1 to MC6 along with twenty singletons. The locus MLVA-AB_2396 demonstrated the highest Simpson’s diversity index value at 0.829 among all loci tested in this study while also having one of the highest variety of tandem repeat species.ConclusionThe molecular diversity and clonal affinities within the genomes of the CRAB strains were clearly evident, with the identification of ST1144Ox, ST1658Ox, and ST1646Oxqaq representing novel findings.
Cardioneuroablation for successful treatment of symptomatic bradycardia in a 12-year-old child after a 6-month follow-up
Authors: Xu Xin , He Shuang , Liu Qian , Liu Ruixi , Zhang Lei , Chen Weijie , Yin Yuehui , Lu Tiewei 
Published: November 2023

BackgroundCardioneuroablation (CNA) is recognized as a promising therapeutic option for adults with severe symptomatic bradycardia caused by excessive vagal tone. However, no pediatric cases have been reported to date. Therefore, the aim of this study is to evaluate the feasibility and efficacy of CNA in children.MethodsA 12-year-old male patient was hospitalized with symptoms of fatigue, palpitations, and syncope for more than 2 months, and was definitively diagnosed with functional sinoatrial node dysfunction by using a 12-lead electrocardiogram, 24-h Holter monitoring, loading dose of atropine test (0.04 mg/kg), and treadmill exercise test. Simultaneously, whole-exome sequencing was performed on the child and his core family members. After completing the preoperative examination and signing the informed consent form, the child underwent CNA therapy.ResultsFirst, the electroanatomic structures of both atria were mapped out by using the Carto 3 system, according to the protocol of purely anatomy-guided and local fractionated intracardiac electrogram–guided CNA methods. Then, the local fractionated intracardiac electrograms of each cardiac ganglionated plexus (GP), including the GP between the aortic root and the medial wall of the superior vena cava, the GP between the posterior wall of the coronary sinus ostium and the left atrium, the GP between the anterior antrum of the right superior pulmonary vein and the superior vena cava, the GP in the superolateral area around the root of the left superior pulmonary vein, the GP around the root of the right inferior pulmonary vein, and the GP around the root of the left inferior pulmonary vein, were used as targets for ablation at a power of 30 W with an ablation index of 350–400. At a 6-month follow-up, the child's heart rhythm saw a complete restoration to sinus rhythm and clinical symptoms disappeared.ConclusionThe first application of CNA in a child with symptomatic sinus bradycardia was achieved with better clinical outcomes. CNA can be carried out cautiously in children under suitable indications.
Association of lipoprotein(a) with left ventricular hypertrophy assessed by electrocardiogram in adults: a large cross-sectional study
Authors: Yan Xuejiao , Gong Jing , Wang Zhenwei , Wang Fangfang , Qi Chunjian 
Published: December 2023

Background and aimsIncreasing evidence supports a causal relationship between lipoprotein(a) [Lp(a)] and atherosclerotic cardiovascular disease, yet its association with left ventricular hypertrophy (LVH) assessed by electrocardiogram (ECG) remains unknown. The aim of this study was to explore the relationship between Lp(a) and LVH assessed by ECG in general population.Methods and resultsIn this cross-sectional study, we screened 4,052 adults from the participants of the third National Health and Nutrition Examination Survey for analysis. Lp(a) was regarded as an exposure variable. LVH defined by the left ventricular mass index estimated from ECG was considered as an outcome variable. Multivariate logistic regression and restricted cubic spline (RCS) were used to assess the relationship between Lp(a) and LVH. Individuals with LVH had higher Lp(a) compared to individuals without LVH (P&lt; 0.001). In the fully adjusted model, Lp(a) was strongly associated with LVH when as a continuous variable (per 1-unit increment, OR: 1.366, 95% CI: 1.043-1.789, P = 0.024), and higher Lp(a) remained independently associated with a higher risk of LVH when participants were divided into four groups according to quartiles of Lp(a) (Q4 vs Q1, OR: 1.508, 95% CI: 1.185-1.918, P = 0.001). And in subgroup analysis, this association remained significant among participants&lt; 60 years, ≥ 60 years, male, with body mass index&lt; 30 kg/m2, with hypertension and without diabetes (P&lt; 0.05). In addition, we did not observe a nonlinear and threshold effect of Lp(a) with LVH in the RCS analysis (P for nonlinearity = 0.113).ConclusionLp(a) was closely associated with LVH assessed by ECG in general population.
Quantitation of olefins in sustainable aviation fuel intermediates using principal component analysis coupled with vacuum ultraviolet spectroscopy
Authors: Kosir Shane , Feldhausen John , Bell David , Cronin Dylan , Boehm Randall , Heyne Joshua 
Published: December 2023

Olefins, a common intermediate from biomass conversion processes, are undesirable in jet fuel because of their poor thermal stability. This paper presents an approach for olefin quantitation using 2D gas chromatography coupled with vacuum ultraviolet spectroscopy. Principal component analysis was used to reduce the dimensionality of the spectroscopic data from a highly olefinic fuel intermediate. A principal component template was created that enabled olefin quantitation, which was compared to the existing GCxGC-VUV approach from the literature. The principal component method was able to identify and quantify trace amounts of cyclodienes, which were present at only 0.01 wt% in the fuel sample. The principal component approach also identifies species that fall outside of the GCxGC template. For instance, quantitation with the literature method resulted in an olefin concentration of 0.95 times that of the principal component method due to olefins falling outside of the expected GCxGC regions. The principal component results were compared with 13C and 1H NMR data, which confirmed that the fuel had a high concentration of olefins and alkanes with little aromatic content.