bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparison of transseptal puncture using a dedicated RF wire versus a mechanical needle with and without electrification in an animal model
Authors: Knight Bradley P. , Wasserlauf Jeremiah , Al‐Dujaili Saja , Al‐Ahmad Amin 
Published: October 2023

AbstractIntroductionMechanical force to achieve transseptal puncture (TSP) using a standard needle may lead to overshooting and injury, and can potentially be avoided using a radiofrequency (RF)‐powered needle or wire. Applying electrocautery to needles and guidewires as an alternative to purpose‐built RF systems has been associated with safety risks, such as tissue coring and thermal damage. The commercially available AcQCross needle‐dilator system (Medtronic) features a sharp open‐ended needle for mechanical puncture, as well as a built‐in connector to enable energy delivery for RF puncture. This investigation compares the safety and efficacy of the AcQCross needle to the dedicated VersaCross RF wire system and generator (Baylis Medical/Boston Scientific).MethodsIn an ex vivo porcine model, VersaCross wire punctures were performed using 1 s, constant mode (approx. 10 W) with maximum two attempts. AcQCross punctures were performed by applying energy for 2 s using a standard electrosurgical generator at 10 W (max. five attempts), 20 W (max. two attempts), and 30 W (max. two attempts). Efficacy was assessed in terms of puncture success and a number of energy applications required for TSP. Safety was assessed quantitatively as force required for TSP, energy required to puncture, and incidence of tissue coring, as well as by qualitative assessment of puncture sites. Additional qualitative observation of tissue cores and debris were obtained from TSP performed in live swine.ResultsRF TSP was 100% successful using the VersaCross wire with 1.0 ± 0.0 attempts. When power was used with the AcQCross needle, it failed to puncture at low (10 and 20 W) power settings; TSP was achieved with 30 W of energy with 91% success using 1.53 ± 0.51 attempts (p < .05 vs. VC) with greater variability (F1,33 = 9223.5, p < .0001). Compared to RF puncture using the VersaCross system, mechanical puncture, alone, using the AcQcross needle required six times more force (8 mm additional forward device displacement) to perforate the septum. Qualitative assessment of puncture sites revealed larger defects and more tissue charring with the AcQCross needle at 30 W compared to punctures with VersaCross wire. Tissue coring with the open‐ended AcQCross needle was observed in vivo and measured to occur in 57% of punctures using the ex vivo model; no coring was observed with the closed‐tip VersaCross wire.ConclusionsThe AcQCross needle frequently required higher energy of 30 W to achieve RF TSP and was associated with tissue coring and charring, which have been, previously, reported when electrifying a standard open‐ended mechanical needle or guidewire. These findings may limit safety and effectiveness compared to the VersaCross system.
Comparison of the effect of ethanol infusion into the vein of Marshall between with and without collateral veins
Authors: Ishimura Masayuki , Yamamoto Masashi , Himi Toshiharu , Kobayashi Yoshio 
Published: October 2023

AbstractBackgroundDespite the potential benefits of ethanol infusion into the vein of Marshall (EIVOM) for atrial fibrillation (AF) ablation, concerns about its reversible and unpredictable effects persist.ObjectiveTo assess the effectiveness of EIVOM in the vein of Marshall (VOM) with collateral veins (CVs) during mitral isthmus and AF ablation.MethodsWe included 142 AF patients. EIVOM was performed before radiofrequency ablation, and low‐voltage areas (<0.5 mV) were measured before, immediately after, and 1 h after EIVOM.ResultsAmong the 142 patients, 93 (65%) underwent EIVOM, and among these, 35 (37%) were found to have CVs. In the VOM with CVs group, areas with low voltage measured 0 (0–1.85) cm2 before EIVOM, 6.9 (4.1–11.2) cm2 immediately after EIVOM, and 5.7 (3.5–10.6) cm2 1 h after EIVOM. Conversely, in the group designated as VOM without CVs—from which the nine leakage cases were excluded—the areas measured 0 (0–1.35) cm2, 5.5 (2.6–11.8) cm2, and 4.7 (1.8–13.5) cm2 at the respective time points. MI line block was fully achieved in 89% (31/35) of cases in the VOM with CVs group and 88% (44/49) in the VOM without CVs groups (p = .94). There was no significant difference in the outcome of AF ablation between these groups (log‐rank p = .73). Additionally, no significant difference was observed between EIVOM (+) and EIVOM (−) groups (log‐rank p = .59).ConclusionEIVOM effectively creates MI line block, and its beneficial effects are sustained for at least 1 h after the procedure despite the low‐voltage areas showing a slight reduction in size.
A novel cricket morph has diverged in song and wing morphology across island populations
Authors: Gallagher James H. , Zonana David M. , Broder E. Dale , Syammach Aziz M. , Tinghitella Robin M. 
Published: October 2023

Abstract
Divergence of sexual signals between populations can lead to speciation, yet opportunities to study the immediate aftermath of novel signal evolution are rare. The recent emergence and spread of a new mating song, purring, in Hawaiian populations of the Pacific field cricket (Teleogryllus oceanicus) allows us to investigate population divergence soon after the origin of a new signal. Male crickets produce songs with specialized wing structures to attract mates from afar (calling) and entice them to mate when found (courtship). However, in Hawaii, these songs also attract an eavesdropping parasitoid fly (Ormia ochracea) that kills singing males. The novel purring song, produced with heavily modified wing morphology, attracts female crickets but not the parasitoid fly, acting as a solution to this conflict between natural and sexual selection. We've recently observed increasing numbers of purring males across Hawaii. In this integrative field study, we investigated the distribution of purring and the proportion of purring males relative to other morphs in six populations on four islands and compared a suite of phenotypic traits (wing morphology, calling song and courtship song) that make up this novel signal across populations of purring males. We show that purring is found in varying proportions across five, and is locally dominant in four, Hawaiian populations. We also show that calling songs, courtship songs and wing morphology of purring males differ geographically. Our findings demonstrate the rapid pace of evolution in island populations and provide insights into the emergence and divergence of new sexual signals over time.
Abstract
What occurs immediately following the emergence of a successful new sexual signal? The fleeting nature of these evolutionary events makes them difficult to study, yet they have important implications for our understanding of speciation. Several years ago, a new male cricket morph arose in Hawaii that produced a novel sexual signal (song) using altered wing morphology. This novel ‘purring’ song is attractive to female crickets but protective against a deadly, eavesdropping parasitoid fly, serving as a new private mode of communication among crickets. In this study, we show that despite arising very recently, purring males are now found in multiple populations across Hawaii and have even reached fixation in one. Perhaps surprisingly, we also find that the wings and songs of purring males now differ geographically. The accelerated timeframe in which these changes have occurred provides new insights into how sexual signals can diverge in small island populations.
Life cycle assessment of prospective trajectories: A parametric approach for tailor‐made inventories and its computational implementation
Authors: Douziech Mélanie , Besseau Romain , Jolivet Raphaël , Shoai‐Tehrani Bianka , Bourmaud Jean‐Yves , Busato Guillaume , Gresset‐Bourgeois Mathilde , Pérez‐López Paula 
Published: October 2023

AbstractLife cycle assessment (LCA) is a standardized, holistic, and multi‐criteria approach to estimate the environmental impacts of a system over its entire lifecycle. Modeling the environmental impacts of future scenarios and evolving systems in LCA is challenging due to lack of knowledge around technological evolutions and changing backgrounds influencing the foreground system. The method proposed here tackles these issues by combining parameterized life cycle inventories (LCIs) of foreground and background systems to assess how background changes, for example in the energy sector, affect the environmental impacts of the foreground. First, parameterized LCIs for the heating and energy sector were developed to flexibly estimate the environmental impacts of heating, gas, and electricity trajectories. Assessing their environmental impacts is essential to avoid any burden shifting to other impacts. Thanks to their parameterization, these models can represent different geographical, temporal, or technological contexts. Second, the combination of these parameterized LCIs was implemented using the Python library lca_algebraic, designed to enhance computational efficiency and calculation speed of LCAs. lca_algebraic’s features were extended to link parameters to specific LCIs and, hence, ease their import and export and facilitate teamwork. In a final step, the developed LCIs and lca_algebraic library were used to estimate the environmental impacts of French heating scenarios from 2018 until 2050, as a test of the approach. The parameterized models developed within this work are available on a Git together with published reference datasets for comparison, so that the method can be adapted to evaluate similar energy trajectories for other countries or regions. This article met the requirements for a gold–gold JIE data openness badge described at http://jie.click/badges.
Development and psychometric properties of the Couple Interaction Pattern Scale
Authors: Fang Xiaoyi , Chen Ziyuan , Tong Wei , Gao Caixin , Zhang Hongyu , Li Qingyin 
Published: October 2023

AbstractThis study developed the Couple Interaction Pattern Scale (CIPS) based on the interpersonal theory, comprising five subscales: friendly complementary (FC), hostile complementary (HC), mutual hostile‐dominant (MHD), friendly‐dominant eliciting hostile‐submissive (FDHS), and hostile‐dominant eliciting friendly‐submissive (HDFS). The psychometric properties of the CIPS were examined through three independent studies. Study one conducted item reduction and preliminary analysis using a sample of 662 married individuals, with an additional 80 married individuals for test–retest reliability assessment. Study two validated the scale through 1207 married individuals. In study three, the effect of couple interaction pattern (CIP) on marital quality was analyzed among 310 newlywed couples using the actor–partner interdependence model (APIM). Results supported the construct validity, acceptable internal consistency, and test–retest reliability of the CIPS. Besides, concurrent validity was also proved by associations with conflictual communication patterns, marital quality, stability, emotional connection, and perceived partner support. APIM analysis also supported the association between CIP and marital quality.
Efficacy and tolerability of the American Heartworm Society therapeutic protocol in dogs affected by heartworm disease without caval syndrome
Authors: Romito G. , Pane E. , Guglielmini C. , Poser H. , Valente C. , Paradies P. , Castagna P. , Mazzoldi C. , Cipone M. 
Published: October 2023

ObjectivesThe American Heartworm Society medical protocol represents the current standard of therapy for canine heartworm disease without caval syndrome. However, data on the tolerability of this protocol are limited. This study aimed to describe efficacy and prevalence of possible treatment‐related side effects in dogs with heartworm disease treated using the American Heartworm Society protocol.Materials and MethodsFor this retrospective multi‐centre cohort study, dogs diagnosed with classes 1 to 3 heartworm disease that completed the American Heartworm Society medical protocol were searched in four medical databases. Demographic, clinical, diagnostic, therapeutic and outcome data, including the number and type of possible treatment‐related side effects, were retrieved.ResultsThirty‐five dogs were included. The median age and bodyweight were 6 years (1 to 13 years) and 17.3 kg (4.9 to 50 kg), respectively. Heartworm disease was classified as classes 1, 2 and 3 in 20 of 35, 11 of 35 and four of 35 dogs, respectively. In addition to the therapeutic recommendations of the American Heartworm Society, eight of 35 dogs underwent sedation to favour melarsomine administration, and 30 of 35 received ice at the injection site. After adulticide therapy, all dogs were hospitalised with cage rest [median time 12 hours (6 to 48 hours)]. All dogs survived the treatment. All dogs with long‐term follow‐up (32/35) became negative. Furthermore, treatment‐related side effects were rare, mild and rapidly recovered without the need for supporting therapies; these included depression/lethargy (4/35 dogs), cough (2/35 dogs) and lameness, pain and gastrointestinal signs (1/35 dog each).Clinical SignificanceThe American Heartworm Society medical protocol is efficient and safe in dogs with classes 1 to 3 heartworm disease.
Giardiasis and diarrhea in dogs: Does the microbiome matter?
Authors: Kuzi Sharon , Zgairy Soha , Byrne Barbara A. , Suchodolski Jan , Turjeman Sondra C. , Park So Young , Aroch Itamar , Hong Mike , Koren Omry , Lavy Eran 
Published: October 2023

AbstractBackgroundGiardia duodenalis (Gd) causes intestinal parasitosis. The involvement of the intestinal microbiome in determining the infection's clinical phenotype is unknown.ObjectiveInvestigate the fecal microbiome features in dogs with giardiasis.Animals and MethodsCross‐sectional study, including fecal samples of kenneled dogs with Gd diagnosed by fecal Giardia antigen dot ELISA. The fecal microbial compositional characteristics and dysbiosis index (DI) were compared between diarrheic and nondiarrheic dogs.ResultsFecal samples of 38 Gd‐infected dogs (diarrheic, 21; nondiarrheic, 17) were included. No differences were found in Faith's phylogenic diversity and beta diversity (weighted UniFrac distances) and in specific taxa abundances at the phylum, genus, and species levels, as well as in alpha and beta diversities between diarrheic and nondiarrheic dogs, and also when divided by sex or age. Among diarrheic dogs, alpha diversity was higher in males than in females (pairwise Kruskal‐Wallis, q = 0.01). Among males, fecal abundances of the genus Clostridium (W = 19) and Clostridium spiroforme species (W = 33) were higher in diarrheic compared to nondiarrheic dogs. In diarrheic dog fecal samples, Proteobacteria were more prevalent (W = 1), whereas Verrucomicrobia were less prevalent in dogs <1 year of age than in older dogs. The fecal sample DI of 19 diarrheic and 19 nondiarrheic dogs was similar (median, −0.2; range, −4.3 to 4.5 and median, −1.0; range, −4.3 to 5.8, respectively).ConclusionsThe fecal microbial composition of symptomatic and asymptomatic dogs with giardiasis is similar. Based on fecal DI, giardiasis is not characterized by prominent dysbiosis. Other host and parasite characteristics might determine the severity of giardiasis in dogs.
The efficacy and safety of cannabidiol as adjunct treatment for drug‐resistant idiopathic epilepsy in 51 dogs: A double‐blinded crossover study
Authors: Rozental Aaron J. , Weisbeck Brooke G. , Corsato Alvarenga Isabella , Gustafson Daniel L. , Kusick Breonna R. , Rao Sangeeta , Bartner Lisa R. , McGrath Stephanie 
Published: October 2023

AbstractBackgroundApproximately 30% of dogs with idiopathic epilepsy (IE) are drug‐resistant. Recent studies have suggested cannabidiol (CBD) may be an effective anticonvulsant in dogs with IE.ObjectiveTo evaluate the addition of CBD to antiseizure drugs (ASDs) on seizure frequency and to report adverse events in dogs with drug‐resistant IE.AnimalsFifty‐one dogs. Dogs having at least 2 seizures per month while receiving at least 1 ASD were included in the trial.MethodsDouble‐blinded placebo‐controlled crossover study. The 5 mg/kg/day dosage met futility requirements after 12 dogs, and a dosage of 9 mg/kg/day was used in the next 39 dogs. Dogs were randomly assigned to receive CBD or placebo for 3 months, with a 1‐month washout period between oils. Total numbers of seizures and seizure days were recorded. Diagnostic testing was performed periodically throughout the trial.ResultsAt the 9 mg/kg/day dose, the decrease in total seizure frequency was significant compared with placebo. A 24.1% decrease in seizure days occurred in dogs receiving CBD and a 5.8% increase occurred in dogs receiving placebo (P ≤ .05). No significant difference was found in the number of responders (≥50% decrease in total seizures or seizure days). Liver enzyme activities increased at both dosages. Decreased appetite and vomiting were more common in the CBD phase (P ≤ .05).Conclusions and Clinical ImportanceCannabidiol decreased total seizures and seizure days compared to placebo when administered to dogs PO at 9 mg/kg/day. Liver enzymes should be monitored with administration of CBD in dogs.
Surgical ciliated cysts of the mandible: A systematic review of case reports
Authors: Brisset Mathieu , Cambronne Clément , Ferrer Mélanie , Cousty Sarah , Dubuc Antoine 
Published: October 2023

AbstractBackgroundSurgical ciliated cysts occur mainly in the maxillae after radical maxillary sinus surgery; they rarely develop in the mandible. This study aims to gather information on all the characteristics of patients suffering from mandibular surgical ciliated cysts. This article also reports two new cases.MethodsPubMed, Google Scholar and the International Clinical Trials Registry Platform were explored until 13 December 2022 for articles regarding mandibular surgical ciliated cysts. Maxillary ciliated cysts were excluded.ResultsFourteen original articles were included in a total of 16 cases. Maxillofacial surgeries are the first aetiology (94.4%). Surgical ciliated cysts of the mandibular region show a 1.25:1 male‐to‐female ratio with a protracted time to diagnosis (range: 2–56 years). Most patients are symptomatic (77.8%). Typically, radiology shows a radiolucency lesion (88.9%) and histology describes pseudostratified ciliated columnar epithelium. Enucleation has always been described as the treatment.DiscussionAll results were case reports, thus a low level of evidence studies. Mandibular surgical ciliated cysts should be considered in patients presenting a mandibular swelling or radiolucency lesion with a maxillofacial surgery history. Meticulous surgical techniques can aid in the prevention of this lesion.
Endofungal bacteria and ectomycorrhizal fungi synergistically promote the absorption of organic phosphorus in Pinus massoniana
Authors: Mei Yan , Zhang Meiling , Cao Gengyue , Zhu Jiale , Zhang Aiyue , Bai Hongyan , Dai Chuanchao , Jia Yong 
Published: October 2023

AbstractEctomycorrhizal fungi (ECMFs) that are involved in phosphorus mobilisation and turnover have limited ability to mineralise phytate alone. The endofungal bacteria in the ectomycorrhizal fruiting body may contribute to achieving this ecological function of ECMFs. We investigated the synergistic effect and mechanisms of endofungal bacteria and ECMF Suillus grevillea on phytate mineralisation. The results showed that soluble phosphorus content in the combined system of endofungal bacterium Cedecea lapagei and S. grevillea was 1.8 times higher than the sum of C. lapagei and S. grevillea alone treatment under the phytate mineralisation experiment. The S. grevillea could first chemotactically assist C. lapagei in adhering to the surface of S. grevillea. Then, the mineralisation of phytate was synergistically promoted by increasing the biomass of C. lapagei and the phosphatase and phytase activities of S. grevillea. The expression of genes related to chemotaxis, colonisation, and proliferation of C. lapagei and genes related to phosphatase and phytase activity of S. grevillea was also significantly upregulated. Furthermore, in the pot experiment, we verified that there might exist a ternary symbiotic system in the natural forest in which endofungal bacteria and ECMFs could synergistically promote phytate uptake in the plant Pinus massoniana via the ectomycorrhizal system.
Clinicopathological features, current status, and progress of primary central nervous system melanoma diagnosis and treatment
Authors: Guo Pengna , Wei Xiaoting , Guo Zhen , Wu Di 
Published: October 2023

AbstractPrimary central nervous system (CNS) melanoma is an extremely rare condition, with an incidence rate of 0.01 per 100,000 individuals per year. Despite its rarity, the etiology and pathogenesis of this disease are not yet fully understood. Primary CNS melanoma exhibits highly aggressive biological behavior and presents clinically in a distinct manner from other types of melanomas. It can develop at any age, predominantly affecting the meninges as the primary site, with clinical symptoms varying depending on the neoplasm’s location. Due to the lack of specificity in its presentation and the challenging nature of imaging diagnosis, distinguishing primary CNS melanoma from other CNS diseases. The combination of challenges in early detection, heightened tumor aggressiveness, and the obscured location of its origin contribute to an unfavorable prognostic outcome. Furthermore, there has been currently no consensus on a standardized treatment approach for primary CNS melanoma. Despite recent advancements in targeted therapy and immunotherapy for CNS melanoma, patients with primary CNS melanoma have limited treatment options due to their inadequate response to these therapies. Here, we provided a comprehensive summary of the epidemiology, clinical features, molecular pathological manifestations, and available diagnostic and therapeutic approaches of primary CNS melanoma. Additionally, we proposed potential therapeutic strategies for it.
Comparative study of virulence factors, pathogenicity and genetic diversity ofAcidovorax avenaesubsp. avenae, the causal agent of red stripe disease in sugarcane
Authors: Bertani Romina Priscila , Mielnichuk Natalia , Chaves Solana , Yaryura Pablo Marcelo , Joya Constanza María , Monachesi María Angélica , Vojnov Adrian Alberto , González Victoria , Perera María Francisca 
Published: October 2023

AbstractAcidovorax avenaesubsp. avenae(Aaa) is the causal agent of red stripe in sugarcane, a disease characterized by two forms: leaf stripe and top rot. Despite the importance of this disease, little is known about Aaa infection mechanisms, and studies of virulence factors (VFs) have not been reported. Previous analysis of Aaa isolates obtained from sugarcane fields in Tucumán, Argentina, suggested that pathogenicity was not related to genetic groups determined by rep‐PCR analysis. Therefore, the aims of this work were to analyse VFs produced by Aaa strains from different genetic groups and to evaluate the association among VFs, between VFs and Aaa pathogenicity and between VFs and Aaa genetic diversity. Bacterial motility (sliding, swimming and twitching), extracellular enzyme activities (proteases, amylases and endoglucanases), H2O2‐mediated oxidative stress, cell adhesion and exopolysaccharide (EPS) production were assayed in 14 Aaa isolates from different genetic groups. Pearson's correlation analysis and principal component analysis (PCA) were performed. For each VF analysed, values were variable presenting quantitative traits among the strains. Significant correlations were observed among the VFs, though no clear trend was identified between them and the pathogenicity or genetic group. Results reinforce the idea that a single VF does not account for the infection outcome, but a more complex process occurs where the interplay among VFs must be considered. The results of this study are crucial because they provide insight into the infection mechanism of this bacterium.