bluuebunny/crossref_metadata_2025_split huggingface dataset:
PHÂN TÍCH CHI PHÍ HIỆU QUẢ CỦA ROSUVASTATIN SO VỚI ATORVASTATIN TRONG ĐIỀU TRỊ RỐI LOẠN LIPID MÁU TẠI VIỆT NAM
Authors: Nguyễn Xuân Nam , Nguyễn Đức Trung , Nguyễn Thu Hường , Nguyễn Thị Diễm Chi 
Published: November 2023

Đặt vấn đề: Tăng cholesterol máu là một trong những yếu tố nguy cơ quan trọng nhất có thể thay đổi được trong phòng ngừa các bệnh tim mạch. Điều trị rối loạn lipid máu phải kết hợp thay đổi lối sống và dùng thuốc. Do đó nghiên cứu này tập trung vào việc đánh giá chi phí hiệu quả của việc sử dụng rosuvastatin so với atorvastatin trong điều trị rối loạn lipid máu tại Việt Nam. Phương pháp nghiên cứu: Nghiên cứu sử dụng mô hình cây quyết định, so sánh chi phí hiệu quả giữa sử dụng rosuvastatin và atorvastatin trong điều trị rối loạn chuyển hóa lipid máu. Thời gian điều trị tính từ sử dụng thuốc cho đến lúc đạt LDL-C mục tiêu. Số liệu được lấy từ tổng quan tài liệu dựa trên các cơ sở dữ liệu. Khung thời gian đánh giá của mô hình là một năm. Chu kỳ được tính trên một chu kỳ đạt LDL-C mục tiêu của bệnh. Kết quả: rosuvastatin có hiệu quả lâm sàng tốt hơn so với atorvastatin trong chỉ định điều trị rối loạn chuyển hóa lipid máu. Theo quan điểm bảo hiểm y tế cho thấy trong điều trị LDL-C, rosuvastatin chiếm ưu thế vừa tiết kiệm về mặt chi phí, vừa tăng về hiệu quả điều trị. Cụ thể, khi điều trị bằng rosuvastatin, giúp tiết kiệm được gần 34,5 triệu đồng trên 1 đơn vị hiệu quả tăng thêm . Kết quả phân tích độ nhạy một chiều và độ nhạy xác suất khẳng định trong đa số trường hợp, sử dụng rosuvastatin đều vượt trội so với atorvastatin. Kết luận: Rosuvastatin vừa có hiệu quả lâm sàng tốt hơn, với mức chi phí điều trị thấp hơn so với atorvastatin khi giúp khả năng bệnh nhân đạt mức LDL-C mục tiêu tốt hơn. Nghiên cứu còn hạn chế khi các dữ liệu đầu vào dựa trên tổng quan tài liệu.
VAI TRÒ THỞ MÁY ÁP LỰC DƯƠNG LIÊN TỤC TRONG ĐIỀU TRỊ SUY TIM NẶNG CHO BỆNH NHÂN TIM BẨM SINH CÓ TĂNG LƯU LƯỢNG MÁU LÊN PHỔI
Authors: Đoàn Thị Linh , Lê Hồng Quang , Nguyễn Ngọc Sáng , Nguyễn Thị Vân Anh , Phạm Thị Ngọc Anh , Ngô Thanh Huyền 
Published: November 2023

Mục tiêu: Nhận xét vai trò Đánh giá hiệu quả của thở máy áp lực dương liên tục đường mũi (N-CPAP) trong điều trị bệnh nhân suy tim nặng do bệnh tim bẩm sinh nhóm tăng lưu lượng máu lên phổi. Đối tượng và phương pháp nghiên cứu: Nghiên cứu mô tả cắt ngang kết hợp can thiệp (E ko rõ co nên sử dụng cái này ko: Nghiên cứu bán thực nghiệm một nhóm) được tiến hành từ tháng 08 năm 2021 đến tháng 07 năm 2022 để đánh giá tính hiệu quả của liệu pháp điều trị suy tim nằng (độ IV) sử dụng N-CPAP cho tất cả các bệnh nhân từ 2 tháng đến 16 tuổi chẩn đoán mắc tim bẩm sinh nhóm tăng lưu lượng máu lên phổi tại đơn nguyên Điều trị tích cực Tim mạch Nội khoa- Khoa Nội tim mạch - Trung tâm Tim mạch - Bệnh viện Nhi Trung ương. Kết quả: Tổng số có 42 bệnh nhân được nghiên cứu, tuổi từ 2 tháng đến 60 tháng tuổi, tuổi trung bình là 5.49 ± 4,6 tháng, cân nặng trung bình 8,32 ± 5,67 kg. Bệnh thường gặp nhất là thông liên thất (33,2%). Tỷ lệ thở N-CPAP thành công là 29 bệnh nhân (69%), thất bại là 13 bệnh nhân (31%), với thời gian nằm viện trung bình 7,26 ± 5,67 ngày với nhóm thành công và 14,2 ± 2,8 ngày với nhóm thất bại. Tỷ lệ bệnh nhân suy tim độ IV giảm từ 100% xuống 21,4 % sau điều trị bằng N-CPAP. Tần số tim trước 150,26 ± 19,50 nhịp/phút, sau 125,99 ± 17,07 nhịp/phút, nhịp thở trước là 58,84 ± 4,90 nhịp/phút, sau là 39,96 ± 4,68 nhịp/phút, chỉ số SpO2 trước là 72,93 ± 9,52%, sau là 95,20 ± 7,07 (p < 0,01). Chỉ số khí máu: pH trước là 7,25 ± 0,07 mmHg, sau là 7,38 ± 0,05 mmHg (p < 0,001). Có 2 biến chứng do thở N-CPAP là loét mũi do cố định canuyn là 16,7% và chướng bụng là 11,9%. Kết luận: Thở máy áp lực dương liên tục qua mũi giúp cải thiện mức độ suy tim nặng cho bệnh nhân mắc bệnh tim bẩm sinh nhóm tăng lưu lượng máu lên phổi.
A robust error correction method for numerical weather prediction wind speed based on Bayesian optimization, variational mode decomposition, principal component analysis, and random forest: VMD-PCA-RF (version 1.0.0)
Authors: Zhou Shaohui , Gao Chloe Yuchao , Duan Zexia , Xi Xingya , Li Yubin 
Published: November 2023

Abstract. Accurate wind speed prediction is crucial for the safe and efficient utilization of wind resources. However, current single-value deterministic numerical weather prediction methods employed by wind farms do not adequately meet the actual needs of power grid dispatching. In this study, we propose a new hybrid forecasting method for correcting 10 m wind speed predictions made by the Weather Research and Forecasting (WRF) model. Our approach incorporates variational mode decomposition (VMD), principal component analysis (PCA), and five artificial intelligence algorithms: deep belief network (DBN), multilayer perceptron (MLP), random forest (RF), eXtreme gradient boosting (XGBoost), light gradient boosting machine (lightGBM), and the Bayesian optimization algorithm (BOA). We first predict wind speeds using the WRF model, with initial and lateral boundary conditions from the Global Forecast System (GFS). We then perform two sets of experiments with different input factors and apply BOA optimization to tune the four artificial intelligence models, ultimately building the final models. Furthermore, we compare the aforementioned five optimal artificial intelligence models suitable for five provinces in southern China in the wintertime: VMD-PCA-RF in December 2021 and VMD-PCA-lightGBM in January 2022. We find that the VMD-PCA-RF evaluation indices exhibit relative stability over nearly a year: the correlation coefficient (R) is above 0.6, forecasting accuracy (FA) is above 85 %, mean absolute error (MAE) is below 0.6 m s−1, root mean square error (RMSE) is below 0.8 m s−1, relative mean absolute error (rMAE) is below 60 %, and relative root mean square error (rRMSE) is below 75 %. Thus, for its promising performance and excellent year-round robustness, we recommend adopting the proposed VMD-PCA-RF method for improved wind speed prediction in models.
Phantom Mobility: Coercion, Conversion, and Letter Writing in Colonial Sri Lanka
Authors: Portz Josie 
Published: November 2023

Abstract
This article takes a pan-historiographic approach in its analysis of three collections of artifacts in sixteenth- and seventeenth-century Sri Lanka: a set of contact narratives compiled by both the colonizing Portuguese and the dominant people group of the island, the Sinhalese; correspondence between King Dharmapāla and Pope Gregory XIII; and correspondence between the Sinhalese poet Alagiyavanna Mukaveti and King Philip III. In bringing together narratives of first contact between colonizers and colonized and letters from members of the Sinhalese elite requesting the restitution of land by the Portuguese colonizers, this article showcases examples in which local Sri Lankans performed rhetorical resistance through subversive means. In examining these artifacts, I offer for consideration the concept of “phantom mobility,” a rhetorical strategy that creates the appearance (and sometimes the illusion) of movement. In this rhetorical strategy, movement is conceived in terms of proximity or distance in relation to persons, places, events, etc. In this article, I suggest that phantom mobility can help illuminate how rhetors navigate colonial power dynamics in ways that expand our reading of rhetorical texts.
A Study on Influencing Factors and Challenges of Ethics in Business in Indian Context
Authors: Jyoti Mishra  
Published: November 2023

In order to survive and grow in the market, moral values are one thing which must be taken into consideration along with the vision set up by Organization. From a business point of view each and every organization tries to achieve the main goal, which obviously is to ‘maximize the profit’. But while doing so these organizations should also consider their moral, ethical and social obligations. Business ethics refers to the principles, values, and moral standards that guide the behavior and conduct of individuals and organizations within the business environment. As economies evolve and global markets expand, the role of ethical behavior in business becomes increasingly important. Ethics support indirectly to the growth of the Organizations. In this era of sustainability, ethics is the power in the hands of organizations to achieve sustainable practices.
This research paper aims to explore the various influencing factors and challenges that impact ethical practices within the world of business. The study examines various internal and external elements affecting ethical decision-making processes among businesses, analyzes the implications of these factors on corporate behavior, and suggests potential strategies to promote ethical practices. It is an exploratory & descriptive study completed massively with the help of Secondary data. The paper encompasses the world of Ethics in Business & describes the associated factors & challenges. The Author has suggested a recommendary model stating the essence of ethics in business and the approaches required to achieve the same. The Author has considered industries at large and the same may be the limitations of the study as the inferences are indicative in nature rather exhaustive. Ethics have a strong role to play in the world of Business, this attempts to generate insights in this respect.
Fomentar las habilidades de programación y pensamiento computacional: una acción formativa para futuros docentes de educación infantil
Authors: Esteve-Gónzalez Vanessa , Borrull Anna , Valls Cristina 
Published: November 2023

<p>La integración de actividades de programación por bloques en entornos de aprendizaje colaborativo promueve el desarrollo del pensamiento computacional (PC). Este estudio descriptivo presenta una acción formativa virtual mediante <em>ScratchJr</em> como herramienta educativa para desarrollar el PC. Una muestra de 81 estudiantes del grado de educación infantil elaboró propuestas didácticas sobre flora y fauna orientadas a desarrollar el PC. La evaluación de estas se realizó mediante la evaluación 360º usando una rúbrica basada en el modelo TPACK. Los futuros docentes fueron capaces de desarrollar propuestas didácticas, aunque les costó aplicar algunos de los ítems relacionados con el conocimiento tecnológico del contenido. La aplicación del <em>flipped-learning</em> permitió una mejor interacción entre estudiantes y entre docentes y estudiantes, así como una gestión más eficiente del conocimiento y del aprendizaje. La experiencia fue valorada positivamente por el alumnado, que considera fundamental ser competentes en el desarrollo de estrategias didácticas basadas en el PC.</p>
Influencia de la autoeficacia académica sobre la adaptación a la universidad: rol mediador del agotamiento emocional académico y del engagement académico
Authors: Dominguez-Lara Sergio , Gravini-Donado Marbel , Moreta-Herrera Rodrigo , León Segundo R. 
Published: November 2023

<p>El objetivo de esta investigación fue analizar el rol mediador del agotamiento emocional académico (AEM) y del engagement académico (EA) en la influencia de la autoeficacia académica (AA) sobre las dimensiones de la adaptación a la universidad (AU) en estudiantes universitarios peruanos de nuevo ingreso. Participaron 688 estudiantes de universidades privadas (56.105% mujeres; <em>M<sub>edad</sub></em> = 19.576; <em>DT<sub>edad</sub></em> = 5.230). El análisis de datos se realizó mediante un análisis de regresión estructural y los parámetros se interpretaron bajo una perspectiva de magnitud del efecto. Respecto a los resultados, sin considerar los mediadores, se encontró que existe una influencia significativa de la AA sobre todas las dimensiones de la AU. Por otro lado, y al considerar al rol mediador del AEM y del EA dentro del modelo, solo se encontró una influencia indirecta y significativa de la AA a través del EA sobre tres dimensiones de la AU (académica, institucional y social). En conclusión, el EA media la influencia de la AA sobre las dimensiones de la AU, mientras que el rol mediador del AEM no está clarificado.</p>
A Giant Lipoma in the Distal Forearm of a Cadaver
Authors: Natsis Konstantinos , Achlatis Vlasios , Piagkou Maria , Totlis Trifon 
Published: November 2023

Objective. Lipomas are very common tumors which usually prefer the upper limbs and, depending on their size, may cause nerve compression, or may be asymptomatic. The current cadaveric report describes a giant lipoma in the distal forearm area.
Case Report. A large mass (5.1 × 3.2 × 1.6 cm) was identified on the palmar surface of the distal forearm, during dissection of a 63-year-old male cadaver. The mass caused anteromedial displacement and flattening of the median nerve (MN). Despite the lack of information about the subject’s medical history, MN compression was assumed on the basis of the lipoma’s size, its vicinity to neural structures, and the MN displacement and flattening.
Conclusion. The enlarged distal forearm lipoma, located adjacent to the carpal tunnel, displaced and flattened the MN. The cadaveric finding described is clinically relevant for both differential diagnosis and surgical treatment of carpal tunnel syndrome.
PROFIL ASAM LEMAK DARI Ulva reticulata dan Turbinaria ornate YANG BERASAL DARI PERAIRAN MOUDOLUNG KABUPATEN SUMBA TIMUR [Fatty Acid Profile of Ulva reticulata and Turbinaria ornate From Moudolung waters East Sumba District]
Authors: Yiwa Andro , Meiyasa Firat 
Published: November 2023

Perairan Sumba Timur kaya akan biodiversitas hayatinya termasuk perairan Moudolung. Makroalga yang tersebar di perairan Moudolung cukup melimpah. Untuk pemanfaatannya di bidang pangan perlu dikaji kompenen yang terkandung pada makroalga tersebut. Dengan demikian, tujuan dari penelitian ini adalah mengevaluasi profil asam lemak dari Ulva reticulata dan Turbinaria ornate yang berasal dari perairan Moudolung. Sampel yang berasal dari perairan Moudolung dicuci kemudian dikeringkan 2-3 hari dengan bantuan sinar matahari. Setelah kering sampel tersebut ditepungkan kemudian dilakukan pengujian profil
asam lemak dengan menggunakan instrumen gas chromatography (GS). Hasil pengujian profil asam lemak pada penelitian ini meliputi 51 jenis profil asam lemak Hasil penelitian menunjukkan bahwa total asam lemak dari Ulva reticulata dan Turbinaria ornate masingmasing sebesar 1,41% dan 3,66% dengan persentase totas asam lemak jenuh dan asam lemak tak jenuh masing-masing sebsesar 0,27% - 1,00% dan 1,14% - 2,66%
Pengaruh Kedisiplinan, Kepemimpinan dan Lingkungan Kerja terhadap Kinerja Karyawan
Authors: Perkasa Didin Hikmah , Arbaina Ceci , Purwanto Setiyo , Sari Ovi Hamidah , Tarmiji Achmad 
Published: November 2023

Kinerja menjadi salah satu bahan kajian dalam berbagai aspek khususnya dalam pengelolaan manajemen sumber daya manusia. Penelitian ini bertujuan untuk mengetahui dan menganalisis pengaruh Kedisiplinan, Kepemimpinan dan Lingkungan Kerja Terhadap Kinerja Kariyawan (Studi Pada BPJS Ketenagakerjaan Cabang DKI Jakarta). Desain penelitian menggunakan metode kuantitatif kausal yaitu mengetahui pengaruh antar variable yang diteliti. Alat pengumpulan data mengunakan kuisioner yang telah diuji validitas dan reliabilitasnya yang disebarkan kepada karyawan BPJS Ketenagakerjaan Cabang DKI Jakarta. Populasi yang diteliti pada penelitian ini sebanyak 50 orang, sedangkan sampel yang digunakan sebanyak 50 orang menggunakan teknik sampling jenuh. Analisis data dilakukan dengan menggunakan Smart-PLS (Partial Least Square) melalui pengujian outer model, inner model dan uji hipotesis. Tahap pertama membuat instrument penelitian pada masing-masing variable yang akan diteliti. Tahap kedua menguji instrument variable Kedisiplinan, Kepemimpinan, dan Lingkungan Kerja terhadap Kinerja Kariyawan. Hasil penelitian menunjukkan bahwa Kedisiplinan dan Kepemimpinan Berpengaruh terhadap Kinerja Karyawan, sedangkan Lingkungan kerja tidak berpengairuh terhadap kinerja karyawan.
ANALISIS INTERAKSI SPASIAL EKONOMI DI KAWASAN KEDUNGSEPUR
Authors: Hidayah Nurul , Gunanto Edy Yusuf Agung 
Published: November 2023

Kawasan Kedungsepur merupakan kawasan dengan kontribusi PDRB tertinggi di Provinsi Jawa Tengah, dengan kondisi yang strategis tersebut sangat berpotensi mendorong terjadinya proses interaksi spasial yang tinggi di Kawasan tersebut. Penelitian ini bertujuan untuk menganalisis interaksi spasial ekonomi Kabupaten/Kota dan menganalisis keterkaitan sektor ekonomiÂ masing-masing Kabupaten/Kota dalam Kawasan Kedungsepur. Metode yang digunakan di dalam penelitian ini adalah analisis gravitasi dan indeks moranâ€™s. Hasil perhitungan dari analisis gravitasi Kota semarang memiliki nilai kekuatan yang paling tinggi disusul dengan Kabupaten Kendal, Kabupaten Semarang, Kabupaten Demak, Kabupaten Grobogan dan yang terakhir Kota Salatiga. Selanjutnya pada metode indeks moranâ€™s diperoleh hasilÂ bahwa dalam sektor premier, Kabupaten Demak dan kabupaten Grobogan masuk dalam kategori high-high, Kabupaten Semarang dan Kabupaten Kendal masuk dalam kategori high-low, dan Kota Semarang dan Kota Salatiga masuk dalam kategori low-high. Sedangkan dalam sektor sekunder dan tersier, Kota Semarang menjadi satu-satunya wilayah yang masuk dalam kategori high-low, Kabupaten Semarang, Kabupaten Kendal dan Kabupaten Demak masuk dalam kategori low-high, sedangkan Kota Salatiga dan Kabupaten Grobogan masuk dalam kategori low-low
Cost-Effectiveness Analysis of Myopia Progression Interventions in Children
Authors: Agyekum Sylvia , Chan Poemen P. , Adjei Prince E. , Zhang Yuzhou , Huo Zhaohua , Yip Benjamin H. K. , Ip Patrick , Wong Ian C. K. , Zhang Wei , Tham Clement C. , Chen Li Jia , Zhang Xiu Juan , Pang Chi Pui , Yam Jason C. 
Published: November 2023

ImportanceSeveral interventions exist for treating myopia progression in children. While these interventions’ efficacy has been studied, their cost-effectiveness remains unknown and has not been compared.ObjectiveTo determine cost-effective options for controlling myopia progression in children.Design, Setting, and ParticipantsIn this cost-effectiveness analysis, a Markov model was designed to compare the cost-effectiveness of interventions for controlling myopia progression over 5 years from a societal perspective in a simulated hypothetical cohort of patients aged 10 years with myopia. Myopia interventions considered included atropine eye drops, 0.05% and 0.01%, defocus incorporated multiple segment spectacles, outdoor activity, soft contact lenses (daily disposable and multifocal), rigid gas-permeable contact lenses, progressive addition lenses, bifocal spectacle lenses, orthokeratology, highly aspherical lenslets (HALs), and red light therapy; all interventions were compared with single-vision lenses. Deterministic and probabilistic sensitivity analysis determined the association of model uncertainties with the cost-effectiveness. Costs were obtained from the charges of the Hospital Authority of Hong Kong and The Chinese University of Hong Kong Eye Center.Main Outcome and MeasuresThe mean costs (in US dollars) per child included the cost of hospital visits, medications, and optical lenses. The outcomes of effectiveness were the annual spherical equivalent refraction (SER) and axial length (AL) reductions. Incremental cost-effectiveness ratios (ICERs) were calculated for each strategy relative to single-vision lenses over a time horizon of 5 years.ResultsOutdoor activity, atropine (0.05%), red light therapy, HALs, and orthokeratology were cost-effective. The ICER of atropine, 0.05%, was US $220/SER reduction; red light therapy, US $846/SER reduction; and HALs, US $448/SER reduction. Outdoor activity yielded a savings of US $5/SER reduction and US $8/AL reduction. Orthokeratology resulted in an ICER of US $2376/AL reduction.Conclusions and RelevanceThese findings suggest that atropine eye drops, 0.05%, and outdoor activity are cost-effective for controlling myopia progression in children. Though more expensive, red light therapy, HALs, and orthokeratology may also be cost-effective. The use of these interventions may help to control myopia in a cost-effective way.
Adhesive, Flexible, and Fast Degradable 3D‐Printed Wound Dressings with a Simple Composition
Authors: Hu Yu , Tang Hao , Xu Nan , Kang Xiaowo , Wu Weijun , Shen Chuhan , Lin Junsheng , Bao Yinyin , Jiang Xingyu , Luo Zhi 
Published: November 2023

Abstract3D printing technology has revolutionized the field of wound dressings, offering tailored solutions with mechanical support to facilitate wound closure. In addition to personalization, the intricate nature of the wound healing process requires wound dressing materials with diverse properties, such as moisturization, flexibility, adhesion, anti‐oxidation and degradability. Unfortunately, current materials used in digital light processing (DLP) 3D printing have been inadequate in meeting these crucial criteria. This study introduces a novel DLP resin that is biocompatible and consists of only three commonly employed non‐toxic compounds in biomaterials, that is, dopamine, poly(ethylene glycol) diacrylate, and N‐vinylpyrrolidone. Simple as it is, this material system fulfills all essential functions for effective wound healing. Unlike most DLP resins that are non‐degradable and rigid, this material exhibits tunable and rapid degradation kinetics, allowing for complete hydrolysis within a few hours. Furthermore, the high flexibility enables conformal application of complex dressings in challenging areas such as finger joints. Using a difficult‐to‐heal wound model, the manifold positive effects on wound healing in vivo, including granulation tissue formation, inflammation regulation, and vascularization are substantiated. The simplicity and versatility of this material make it a promising option for personalized wound care, holding significant potential for future translation.
Blue Emitting CsPbBr3: High Quantum Confinement Effect and Well‐Adjusted Shapes (Nanorods, Nanoplates, and Cubes) toward White Light Emitting Diodes
Authors: Shi Wenbin , Zhang Xiao , Xie Cong , Chen Hsueh Shih , Yang Ping 
Published: November 2023

AbstractControlled nucleation and slow growth endow blue emitting CsPbX3 nanocrystals (NCs) with bright photoluminescence (PL), which is crucial needed in luminescent devices. In this paper, a low‐temperature injection synthesis method is developed to control nucleation and the growth process by decreasing the reaction rate of ions, thereby controlling the morphologies of CsPbX3 NCs in clusters, nanorods (NRs), nanoplates (NPLs), and nanocubes by adjusting precursors, ligands, and injection parameters. CsPbX3 NCs exhibit excellent PL properties such as high quantum confinement effect. The PL peak wavelengths of CsPbBr3 NPLs and NRs are at 451 and 467 nm, respectively, in which their full width at half maximum (FWHM) of PL spectra is 22 and 12 nm, while their PL efficiencies are 65 and 74%, respectively. The method is further used to create CsPbI3 and CsPbCl3. CsPbI3 NPLs and NRs reveal PL peaks at 590 and 600 nm and PL efficiencies of 56% and 60%, respectively. These NCs exhibit excellent stability against ultraviolet light irradiation. A color conversion layer for white light‐emitting diodes is fabricated using these highly bright NCs. A Commission Internationale d'Eclairage color coordinate of (0.31,0.33) is located at the white light region specified by Rec.2020 standard, and the color temperature reaches 6189 K.