bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors and clinical correlates of sensory dysfunction in preschool children with and without autism spectrum disorder
Authors: Wiggins Lisa D. , Overwyk Katie , Daniels Julie , Barger Brian , Crain Hayley , Grzadzinski Rebecca , Moody Eric , Reynolds Ann , Reyes Nuri , Rosenberg Cordelia , Rosenberg Steven , Pazol Karen 
Published: December 2023

AbstractSensory dysfunction is a common feature of autism spectrum disorder (ASD). The objectives of this analysis were to examine risk factors and clinical correlates of sensory dysfunction in preschool children with and without ASD. Children aged 2–5 years were enrolled in a multi‐site case–control study. Data were collected in eight areas across the United States in three phases. Caregivers completed an interview with questions on assisted delivery, maternal alcohol use, maternal anxiety during pregnancy, pregnancy weight gain, neonatal jaundice, preterm birth, and child sensory diagnosis given by a healthcare provider. Caregivers also completed an interview and questionnaires on sensory symptoms and clinical correlates of sensory dysfunction in their child. There were 2059 children classified as ASD, 3139 as other developmental delay or disability (DD), and 3249 as population comparison (POP). Caregivers reported significantly more sensory diagnoses and sensory symptoms in children classified as ASD than DD or POP (23.7%, 8.6%, and 0.8%, respectively, for a sensory diagnosis and up to 78.7% [ASD] vs. 49.6% [DD] for sensory symptoms). Maternal anxiety during pregnancy and neonatal jaundice were significantly associated with a sensory diagnosis and certain sensory symptoms in children with ASD and DD. Children's anxiety, attention deficits/hyperactivity, and sleep problems were significantly albeit subtly correlated with both a sensory diagnosis and sensory symptoms in children with ASD and DD. These findings support sensory dysfunction as a distinguishing symptom of ASD in preschool children and identify risk factors and clinical correlates to inform screening and treatment efforts in those with atypical development.
Simultaneous determination of five compounds of fried Radix Paeoniae Alba extract in beagle dogs plasma by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry and its application in a pharmacokinetic study
Authors: Cheng Wenhao , Yuan Zheng , Wu Siyang , Yu Xin , Xia Kexin , Zhao Lifeng , Wang Yuyan , Kang Chen , Yang Wei , Liu Luyang , Li Yingfei 
Published: December 2023

AbstractIn this present study, we developed a reliable and simple ultra‐performance liquid chromatography tandem mass spectrometry (UPLC–MS/MS) assay for the simultaneous quantification of paeoniflorin, albiflorin, oxypaeoniflorin, benzoylpaeoniflorin and isomaltopaeoniflorin in beagle dog plasma. We also analyzed the pharmacokinetics of those components after oral administration of fried Radix Paeoniae Alba (FRPA) in beagle dogs. Plasma samples were processed by protein precipitation with methanol. Chromatographic separation was performed with a Waters HSS‐T3 C18 column (100 × 2.1 mm, 1.8 μm, kept at 40°C) using multiple reaction monitoring mode. A gradient elution procedure was used with solvent A (0.02% formic acid–water) and solvent B (0.02% formic acid–acetonitrile) as mobile phases. Method validation was performed as US Food and Drug Administration guidelines, and the results met the acceptance criteria. The method we establish in this experiment was successfully applied to the pharmacokinetic study after oral administration of FRPA extract to beagle dogs.
Growth, Optical, Thermal, Antibacterial Activity and Computational Study of Highly Efficient Organic NLO Crystal: 2‐Amino‐1‐methyl‐4‐oxo‐4, 5‐dihydro‐1H‐imidazol‐3‐ium 4‐methyl‐benzene‐sulfonate
Authors: Shyla L. , Jebamalar A. S. , Vinitha G. 
Published: December 2023

AbstractA good organic single crystal of 2‐Amino‐1‐methyl‐4‐oxo‐4, 5‐di‐hydro‐1H‐imidazol‐3‐ium 4‐methyl‐benzene‐sulfonate (2ADPTS) is grown by slow evaporation technique, and the orthorhombic system with noncentrosymmetric space group (P212121) is corroborated by single‐crystal X‐ray diffraction analysis. The structural parameters of the 2ADPTS crystal are investigated and weighted up with the theoretical interpretation. The Hydrogen–Hydrogen interaction with (43.6%) in 2ADPTS promotes crystal structure packing stabilization. The presence of various functional groups and chemical composition of the 2ADPTS compound is identified by FTIR and FT‐Raman spectroscopy. The natural bond orbital evaluation interprets all the possible hydrogen bonding interactions and charge delocalizations in the crystal structure. Thermal analysis confirmed the thermal stability of the 2ADPTS crystal. The absorption spectrum of the 2ADPTS crystal is recorded using UV–Vis spectroscopy. The third‐order nonlinear property of the 2ADPTS crystal is confirmed by using the Z‐scan technique. The higher significant antibacterial activity of 2ADPTS is carried out by the standard Kirby‐Bauer test against four pathogenic bacteria commonly called the agar well diffusion process.
A three‐dimensional wideband mmWave multiple‐input multiple‐output channel model for aerial reconfigurable intelligent surface‐assisted communication systems
Authors: Wu Xiaona , Bian Ji , Wang Zili , Zheng Xiangwei , Tian Jie , Qiao Jingping 
Published: December 2023

SummaryThis paper presents a wideband millimeter wave (mmWave) channel model for aerial reconfigurable intelligent surface (ARIS) communications, in which the reconfigurable intelligent surface (RIS) is attached to an unmanned aerial vehicle (UAV) to enable intelligent signal reflections in the air. The model is established according to standard 3GPP channel models and considers important propagation factors, for example, large‐scale fading, small‐scale fading, and radiation pattern of reflection units (RUs). In addition, the model assumes three‐dimensional (3D) rotations of RIS and can capture its effects on channel characteristics. Based on the model, we propose a design method for RIS reflection phases. Statistics including channel amplitude, spatial, temporal, and frequency correlation functions (CFs), and space‐Doppler power spectral density (SD‐PSD) are obtained. The impacts of RU number, UAV height and speed, and RIS rotation on channel statistics are investigated. Results suggest that the designed reflection phases can effectively mitigate multipath fading and Doppler effect. Compared to the yaw angle of the UAV platform, channel characteristics are more sensitive to the roll and pitch angles.
Application of capillary electrophoresis with capacitively contactless conductivity detection for biomedical analysis
Authors: Elbashir Abdalla A. , Osman Abdelbagi , Elawad Mohammed , Ziyada Abobakr K. , Aboul‐Enein Hassan Y. 
Published: December 2023

AbstractThe coupling of capillary electrophoresis (CE) with capacitively coupled contactless conductivity detection (C4D) has become convenient analytical method for determination of small molecules that do not possess chromogenic or fluorogenic group. The implementations of CE with C4D in the determination of inorganic and organic ions and amino acids in biomedical field are demonstrated. Attention on background electrolyte composition, sample treatment procedures, and the utilize of multi‐detection systems are described. A number of tables summarizing highly developed CE‐C4D methods and the figures of merit attained are involved. Lastly, concluding remarks and perspectives are argued.
CSAT‐FRMET: An energy‐efficient hybrid FiWi network‐based 5G model
Authors: Kali Raman Nitin , Saini Himanshi 
Published: December 2023

AbstractHybrid fiber wireless (FiWi) access networks seek to combine the vast amount of bandwidth that is available for optical networks and wireless network mobility; hence, it favors larger bandwidth request but cause the highly nonlinear lagrangian dual problem that decrease energy‐efficient network resilience. Hence, a novel Ceplato‐SAT3 model has been proposed in which the SAT3 algorithm locates the optical network unit (ONU) in an optimal position with high‐speed cost‐efficient placement and weight factor introduced into the position update to improve the exploitation and exploration capability of the algorithm. To prioritize the large bandwidth request during resource allocation, gradient priority justifier requests (GPJR) has been utilized and a novel messaging technique termed flow‐random‐message‐exchanger‐topology (FRMET) provides the index for these prioritized requests depending on QoS parameters such as notification control, reflective QoS attribute (RQA), flow bit rates and maximum packet loss rate thereby decreasing the overhead and eliminate nonlinear langrage dualand perform O2U scheduling to reduce network resilience however synchronization between different ONU clocks may cause upstream data fatal crash at the optical line terminal (OLT). Hence, curl‐trio‐opt control mechanism has been proposed in which the minimization problem is transformed into a joint optimization problem of energy consumption, traffic demand, network requests, and service flow requests by the Lyapunov technique thereby minimizing the upstream data fatal lash. The proposed model has been implemented in Python and the output obtained showed better performance in terms of ONU arrangement, throughput, energy consumption, computation, latency, and error.
A comparison of timing and patterns of treatment failure, and survival outcomes after progression between HPV+ and HPV− patients undergoing chemoradiation for oropharyngeal squamous cell carcinomas
Authors: Laxague Francisco , Zeng Peter Y. F. , Zabihi Dorsa , Fnais Naif , Alshahrani Mohammed , Fung Kevin , MacNeil Danielle , Mendez Adrian , Yoo John , Mymryk Joseph S. , Barrett John W. , Palma David A. , Nichols Anthony C. 
Published: December 2023

AbstractBackgroundWe aimed to analyze and compare the timing and patterns of treatment failure, and survival after progression between HPV‐positive (HPV+) and HPV‐negative (HPV−) patients undergoing chemoradiation for oropharyngeal squamous cell carcinomas (OPSCC).MethodsA retrospective review was performed of all patients undergoing primary chemoradiation for OPSCC between 2008 and 2021. Demographic and clinical data were collected. Kaplan–Meier estimates for overall survival (OS), and time to recurrence/metastases (TTR) were compared using the log‐rank test, with Cox regression used for multivariable modeling comparing HPV+ and HPV− patients.ResultsHPV− patients developed recurrence or metastases at earlier time points than HPV+ patients (8.8 vs. 15.2 months, p < 0.05), due to earlier local/locoregional recurrence and distant metastases, but not isolated regional recurrences. HPV− distant metastases exclusively occurred in a single organ, most commonly the lungs or bone, while HPV+ metastases frequently had multi‐organ involvement in a wide variety of locations (p < 0.05). Once progression (recurrence/metastases) was diagnosed, HPV+ patients experienced superior survival to HPV− patients on univariate and multivariate analysis, largely due to improved outcomes after treatment of local/locoregional recurrences (p < 0.05). There were no differences in survival after isolated regional recurrences or distant metastases.ConclusionHPV+ OPSCC patients relapse later compared to HPV− patients in local/locoregional and distant sites. HPV+ patients with local/locoregional recurrence experience superior survival after recurrence, which does not hold true for isolated regional recurrences or distant metastases. These data can be useful to inform prognosis and guide treatment decisions in patients with recurrent OPSCC.
Characterization of biomarkers in blood serum for cancer diagnosis in dogs using Raman spectroscopy
Authors: Lopes Daniela Franco , Silverio Alessandra , Schmidt Ana Karina Arima , Picca Gerson Baptista , Silveira Landulfo 
Published: December 2023

AbstractBiomarkers of cancer in sera of domestic dogs were detected through Raman spectroscopy with 830 nm excitation. Raman spectra of sera from 61 dogs (31 healthy and 30 with cancer, resulting in 154 and 200 spectra, respectively) were submitted to principal component analysis (PCA) for feature extraction and partial least squares (PLS) regression for discrimination between Healthy and Cancer groups. In the PCA, the peaks at 1132, 1342, 1368, and 1453 cm−1 (albumin and phenylalanine) were higher for the Cancer group. The “redshift” of the peaks at 621, 1003, and 1032 cm−1 (conformational change in proteins and/or bonds at sites close to the aromatic ring of amino acids) occurred in the Cancer group, and the peaks at 451 cm−1 (tryptophan) and 1441 cm−1 (lipids) were higher for the Healthy group. The PLS‐DA classified the serum spectra in Healthy and Cancer groups with high accuracy (78%).
Cytological features of human papillomavirus‐infected immature squamous metaplastic cells from cervical intraepithelial neoplasia grade 2
Authors: Okodo Mitsuaki , Okayama Kaori , Teruya Koji , Shinohara Ruku , Mizuno Shuichi , Settsu Rei , Ishii Yasuyoshi , Fujii Masahiko , Kimura Hirokazu , Oda Mizue 
Published: December 2023

AbstractIn reflex cytology, the presence of prominent nucleoli in immature metaplastic squamous cells (IM) may be underdiagnosed due to variations in interpretation. The aim of this study is to identify human papillomaviruses (HPVs) that infect IM clusters in cervical intraepithelial neoplasia 2 (CIN2) on Papanicolaou (Pap) smears to determine the cytological features of lesion‐derived cells. Thirty‐two patients with a simultaneous diagnosis of CIN2 on biopsy and high‐grade squamous intraepithelial lesions (HSIL) on cytology as well as with IM clusters on HSIL smears were included. CIN2 tissues and HSIL and IM clusters on Pap smears were isolated by manual microdissection, and HPV types were identified by PCR‐based genotyping. The nuclear area within the IM clusters was also measured. The median nuclear area of HPV‐negative IM clusters was 48 μm2, with a coefficient of variation (CV) of 0.20; those of HPV‐positive clusters were 66 μm2 and 0.34, respectively. The cut‐off values of the nuclear area and CV for HPV positivity were 62 μm2 and 0.25, respectively. IM clusters composed of cells with a nuclear area of more than twice that of neutrophils or cells with a wide variation in nuclear sizes are likely to be neoplastic cells caused by HPV.
The Raman spectrum of florencite‐(REE) [REEAl3(PO4)2(OH)6]: An integrated experimental and computational approach
Authors: Ghignone Stefano , Prencipe Mauro , Manzotti Paola , Bruno Marco , Boero Federica , Borghini Alessia , Costa Emanuele , Ciriotti Marco , Scaramuzzo Emanuele 
Published: December 2023

AbstractFlorencite is a hydrous light rare‐earth elements (LREE) aluminium phosphate [REEAl3(PO4)2(OH)6], that amongst the REE‐rich minerals is quite common. The main end‐members are Ce‐, La‐ and Nd‐rich terms that were found in several genetic environments. Despite the large occurrence worldwide, to the authors' knowledge, florencite has attracted very few studies, particularly concerning the characterization of its Raman spectrum. We present a detailed study of the Raman spectrum of florencite, combining experimental measurements and theoretical calculations. Experimental Raman spectra (in the 100–1300 cm−1 spectral range) are measured on four florencite samples characterized by different chemical composition, that is, different REE abundance. The results highlight a remarkable coincidence between different Raman spectra measured on each sample, despite the significantly different chemical compositions in terms of their REE content. The same similarities were also observed in the computed spectra at the ab initio level; moreover, the calculations allowed the attributions of the different Raman signals to specific vibrational modes.
The ASLO Multicultural Program: 34 Years of Leading the Way for Diversity, Equity, and Inclusion Success
Authors: Cuker Benjamin E. , Davis Jeanette , Gibson Deidre 
Published: December 2023

AbstractThe ASLO Multicultural Program (ASLOMP) began in 1990 to promote diversity in the aquatic sciences. It involves brining diverse undergraduate and graduate students to annual ASLO meetings. The students participate in special programing that includes an opening dinner and keynote speaker, a student symposium where they present their work, a field trip, and work with meeting mentors. Between 1990 and 2023, 1443 different students participated in ASLOMP. They were a diverse lot; 43.0% African American, 33.0% Hispanic, 6.4% white, 6.4% Native American, 5.3% Pacific Islander, 3.5% Asian, and 2.4% other. Participants have gone on to be the first persons of color to serve on the ASLO Board of Directors and to assume other leadership positions in the society. Many former ASLOMP participants have gone on for advanced degrees and often return as mentors in the program. The ASLOMP model has been adopted by various other scientific societies including the Ecological Society of America (Strategies for Ecology Education, Diversity and Sustainability ‐ SEEDS), the Society of Wetland Scientists, Sigma Xi, and the Coastal and Estuarine and Research Federation. The founding of ASLOMP demonstrated the usefulness of empowered allies in leading efforts to address issues of diversity, equity, and inclusion.
On the persistence of spatial analyticity for generalized KdV equation with higher order dispersion
Authors: Getachew Tegegne , Tesfahun Achenef , Belayneh Birilew 
Published: December 2023

AbstractPersistence of spatial analyticity is studied for solutions of the generalized Korteweg‐de Vries (KdV) equation with higher order dispersionwhere , are integers. For a class of analytic initial data with a fixed radius of analyticity , we show that the uniform radius of spatial analyticity of solutions at time cannot decay faster than as . In particular, this improves a recent result due to Petronilho and Silva [Math. Nachr. 292 (2019), no. 9, 2032–2047] for the modified Kawahara equation (, ), where they obtained a decay rate of order . Our proof relies on an approximate conservation law in a modified Gevrey spaces, local smoothing, and maximal function estimates.
Wavelet MRE: Imaging propagating broadband acoustic waves with wavelet‐based motion‐encoding gradients
Authors: Le Yuan , Chen Jun , Rossman Phillip J. , Bolster Bradley , Kannengiesser Stephan , Manduca Armando , Glaser Kevin J. , Sui Yi , Huston John , Yin Ziying , Ehman Richard L. 
Published: December 2023

AbstractPurposeTo demonstrate a novel MR elastography (MRE) technique, termed here wavelet MRE. With this technique, broadband motion sensitivity is achievable. Moreover, the true tissue displacement can be reconstructed with a simple inverse transform.MethodsA wavelet MRE sequence was developed with motion‐encoding gradients based on Haar wavelets. From the phase images' displacement was estimated using an inverse transform. Simulations were performed using a frequency sweep and a transient as ground‐truth motions. A PVC phantom was scanned using wavelet MRE and standard MRE with both transient (one and 10 cycles of 90‐Hz motion) and steady‐state dual‐frequency motion (30 and 60 Hz) for comparison. The technique was tested in a human brain, and motion trajectories were estimated for each voxel.ResultsIn simulation, the displacement information estimated from wavelet MRE closely matched the true motion. In the phantom test, the MRE phase data generated from the displacement information derived from wavelet MRE agreed well with standard MRE data. Testing of wavelet MRE to assess transient motion waveforms in the brain was successful, and the tissue motion observed was consistent with a previous study.ConclusionThe uniform and broadband frequency response of wavelet MRE makes it a promising method for imaging transient, multifrequency motion, or motion with unknown frequency content. One potential application is measuring the response of brain tissue undergoing low‐amplitude, transient vibrations as a model for the study of traumatic brain injury.
Dynamic responses and damage evolution of conformal radome composites under blast loading
Authors: Luo Bailu , Wang Ben , Zhang Chundi 
Published: December 2023

AbstractIn this paper, the dynamic responses and damage evolution of two types of conformal radome composites (CRCs), namely single‐window conformal radome (SWCR) and multi‐window conformal radome (MWCR), under blast loading, were investigated using numerical methods. The results show that the local dynamic response of the conformal window is dominating. The window deformation of SWCR is larger than that of MWCR under the same scaled distance, and the MWCR exhibits better blast resistance. The increase in window size causes the reduction of the bending stiffness of CRCs. The obvious stress concentration appears in the notch of carved foam cores, caused by the window effect. The conformal windows are weak parts for the CRCs under the blast loading. It was revealed that the damages of CRCs are mainly concentrated at the edges, center, and diagonal areas of the conformal windows.Highlights
Designed two types of conformal radome composites with hierarchical configuration.
Established the finite element (FE) models of two types of conformal radome composites
Revealed the dynamic responses and damage evolution of conformal radome composites under blast loading.
Effect of GNP coating on carbon fibers on the deformation modes of composites under flexural loading
Authors: Srivastava Alok K. , Singh Aparna 
Published: December 2023

AbstractGraphene nanoplatelets (GNPs) are extremely useful nanofillers in epoxy in carbon fiber‐reinforced polymer (CFRP) composites as they make CFPRs sustain higher loads before failure in different kinds of loading for example flexural, tensile and fatigue. The current study aims to investigate the effect of GNP coating on carbon fibers on the deformation modes of CFRPs under flexural loading. Laminates have been fabricated using vacuum‐assisted resin transfer molding (VARTM) after spray coating GNPs on unidirectional carbon fiber fabrics. One set of flexural tests were carried out where the strain was recorded using DIC and the other set had in‐situ deformation while recording optical images to monitor deformation. Since, the most probable causes of failure under flexural loading are local compression, shear or contact stresses due to a sharp ram, other mechanical tests like compression test and nano‐indentation were also carried out on the composites. Compressive stress–strain response was ascertained using combined loading compression (CLC) fixture and digital image corelation (DIC) while contact response was evaluated using nanoindentation. GNP‐coated CFRPs were shown to have an increase in compressive modulus of 16% and failure strain of 6%, respectively. Axial and transverse strains measured through DIC were more than two times higher in GNP‐coated CFRPs. Nano‐indentation tests across the entire composite showed some data with intermediate modulus (~10–45 GPa) and hardness (~1–5 GPa) between the epoxy and the fiber and this corresponded to an interphase region which was thicker in 0.4GNP laminate compared to pristine laminate. Flexural strength, flexural modulus and strain at maximum stress improved by 10%, 8%, and 9% respectively in GNP‐coated CFRPs compared to uncoated CFRPs. In addition, while pristine laminates showed non‐uniform distribution of strains during flexural loading, the distribution of strains was much more uniform in GNP‐coated laminate. However, in both kinds of laminates, the failure initiation was in the region of compressive bending stresses.Highlights
GNP‐added laminate showed an intermediate modulus and hardness interphase through a nanoindentation test.
Digital image correlation analysis has been performed to obtain the strain maps during compressive and flexural loading.
GNP‐added laminates showed higher failure strains compared to pristine laminates under the compressive loads.
GNP‐added laminates performed well under flexural loading.