bluuebunny/crossref_metadata_2025_split huggingface dataset:
اعتماد البخاري قرينة السماع في رد وقبول الروايات (مختارات من أبواب الطهارة)
Authors: Hafidi Hakima Ahmed , Omara Siham , Mashagba Abd Errahman 
Published: December 2023

Hadith scholars agree on the fact that a narrator hearing a saying from his shaikh is strong evidence of the sanad connection. They also agree that this condition has the highest degree of endurance in proving the connection between the narrator and those who narrated from him. That’s why critic Imams have caringly and carefully used it in judging whether a narration is continuous or disconnected. And Imam al-Bukhari was among those who stipulated hearing as a condition for authenticity, whether in his collective Sahih or his other books like “the Great History” (Attarikh Alkabir) or what was reported from him by his student Imam Al-Tirmidhi in his Al-Ilal Alkabir book, as the latter often asked his Shaikh about his opinion on narrations and he answered him with acceptance or denial based on lack of evidence of hearing between the narrator and his Shaikh, which emphasises the importance of this matter and its research. This is why this research’s objective is to highlight this issue according to Imam Al-Bukhari through what his student Al-Tirmidhi reported from him in the chapters on purification (Attahara), in his two books Al-Ilal Al-Kabir and Al-Jami. Three methods are used in this paper: The inductive method was adopted when collecting the examples mentioned in the study, and the analytical and critical approaches when studying the sayings. Three important conclusions can be mentioned. First, denying or proving that a narrator heard a saying with his own ears is one of the most prominent clues that indicate the connection of the narration chain or its interruption. Second, that Imam al-Bukhari relied on this presumption in accepting and refuting the narrations in most examples of these chapters. Thirdly, that sometimes Imam al-Bukhari does not rely on the presumption of hearing alone in the authentification of the narration, but rather supports it with other evidence.
معاملة المجتمع المسلم الاندونيسي من قبل القرآن والحديث
Authors: Wahid Abdul Hakim 
Published: December 2023

This article aims to learn how Indonesian Muslims treat the Quran and Hadith in their daily lives, and in particular to uncover the secrets of using Surat al-Duha as a means of searching for the missing things. This article was written based on the results of induction using the qualitative and descriptive approach with main sources are the results of interviews with the educator and students of the Islamic Kindergarten Institute, with other sources related to this research. This article concluded that the reason for using Surat al-Duha as a tool to search for something missing has to do with the interpretation of Surat al-Duha reinforced by the Hadith of the Prophet. And The word "lost" considered in the seventh verse which has the meaning of perplexity as a word that contains the power to help man to find the thing that is missing. Although the hadith of the Prophet which confirms the virtue of reading this surah is incorrect, it is even the content in it is proven after its practice. Therefore, this article concludes that many Indonesian society use the Qur'an as a reading to reach their life goals, and uses the Hadith of the Prophet without regard to its authenticity.
The Perspective of Dienul-Islam in Reviewing Leadership for People
Authors: Abdullah Mulyana , Wilodati Wilodati , Abdulhakam Kama , Fitria Ratna 
Published: December 2023

Raising leader is a must at the same time as the demand for muslims. The problem is what are the policies and the act of us as the muslims whose stay and live in a country which it’s not an Islamic state like Indonesia in the case of choosing the leader? Trough the implementing literacy and documentation study to a view of literature and report, this study found that The differences opinion among the clergies seen the one hand emphasized that the charge of muslim is forbidden being raised from among non-muslim. It is also the same with the other who insisted that raised the leader of the people from non-muslims it is permitted. In addressing these difference oppinions, the muslims who stay and live in Indonesia as a country with plural communities, should getting wiser to choose. The thing that most important to be understood is based on welfare for all citizens, there are some common law of syara’.
Games-Based Interactive Multimedia to Increase Student Creativity in Physical Education Course
Authors: Nuraini Sri , Rezaki Rezaki , Marini Arita , Sagita Julius , Safitri Desy , Attas Siti Gomo 
Published: December 2023

This research was conducted using Research and Development method. The purpose of this study is to produce game-based interactive learning media that has a positive impact on improving students' creative thinking skills in physical education courses. Data collection was carried out in several stages, including expert validation, limited trials, and student response questionnaires. Based on the research results, multimedia interactive based on games is proven to improve the creative thinking skills of fourth-grade students at the elementary school of Tugu Utara 05, North Jakarta. Furthermore, multimedia game-based learning positively impacts student creativity use in education. This research contributes to the digitization of elementary schools through the use of technology in the teaching and learning process.
Keyword: game-based interactive learning media; creativity; physical education course
ATATÜRK’ÜN ANKARA’YA GELİŞİ KUTLAMALARI (1932-1938)
Authors: ORAKÇI Meryem 
Published: December 2023

Millî Mücadele sürecinin dönüm noktalarından biri şüphesiz Atatürk’ün 27 Aralık 1919 tarihinde Ankara’ya gelmesidir. Bu tarihten sonra Ankara, meclise ev sahipliği yapmasının yanı sıra Kurtuluş Savaşı’nın komuta merkezi ve yeni Türk devletinin başkenti olmuştur. 1932 yılında bu önemli günün kutlanması, milli bir bayrama dönüştürülmesi gündeme gelmiş ve aynı yıl, ilk kutlama gerçekleşmiştir. Atatürk ve onu karşılayanların hala hayatta olduğu bu yılda öncelikli olarak kutlamanın 1919’daki karşılamaya uygun olmasına önem verilmiştir. Atatürk’ün Cumhurbaşkanı olduğu dönemde yani 1932 ve 1938 arasında kutlanan ilk bayramlar; Cumhuriyet’in tarih, dil ve kültür politikalarının bir yansıması olmuştur. Aynı zamanda Halkevleri vasıtasıyla mümkün olduğunca geniş bir kitleye ulaştırılmıştır. Kutlama amacıyla gerçekleştirilen bazı programlar, günümüze kadar devam eden geleneklere dönüşmüştür.
Bu çalışmada özel olarak Atatürk döneminde yapılan kutlamalar ele alınmıştır. 1932’den 1938’e değin düzenlenen tüm 27 Aralık kutlamaları; dönemin basını, kutlamada etkili olan kişilerin anıları ve inceleme-araştırma kitapları ışığında incelenmiş ve Cumhuriyet’in yeni kültür-sanat politikalarıyla ilişkisi ortaya konmuştur. Bunun yanı sıra, daha sonraki yıllarda gerçekleşen alışılagelmiş bazı kutlama törenlerinin dönemin şartlarında ortaya çıkışı saptanmıştır.
PERFIL EPIDEMIOLÓGICO DA DIABETES MELITTUS NO BRASIL DE 2013 A 2022
Authors: Rezende de Mello Gustavo , Fernandes de Morais Neto Joaquim 
Published: December 2023

Introdução: O Diabetes Mellitus (DM) é uma doença crônica que se caracteriza pelo aumento dos níveis de açúcar (glicose) no sangue, devido à falta ou resistência à ação da insulina, hormônio esse, produzido pelo pâncreas. Os sintomas do Diabetes Mellitus podem variar, mas incluem sede excessiva, aumento da frequência urinária, fadiga, perda de peso inexplicável, visão prejudicada e feridas de cicatrização difícil. Metodologia: Trata-se de um estudo epidemiológico de natureza descritiva, realizado por meio da coleta de dados anuais disponibilizado pelo Sistema de Internação Hospitalar (SIH), banco de dados do Departamento de Informação e Informática do SUS (DATASUS), referentes ao período entre 2013 a 2022, no Brasil. Objetivos: o trabalho tem como intuito analisar o perfil epidemiológico do Diabetes Mellitus no Brasil no período de 2013 a 2022 bem como mostrar a importância da nutrologia, em consonância com a endocrinologia, para tratamento e profilaxia dessa patologia. Resultados: Constatou-se um total de 1.338.851 pessoas com idade entre 60 e 69 anos foram as mais acometidas e quanto ao sexo, mulheres foram mais acometidas por DM. Conclusão: A promoção de hábitos saudáveis, como alimentação equilibrada e atividade física regular, é fundamental para prevenir o desenvolvimento dessa doença e para o controle adequado dos níveis de açúcar no sangue. A conscientização da população e o acesso à assistência médica são cruciais para combater essa epidemia global.
Palavras-chave: Diabetes. Glicemia. Epidemiologia.
PERFIL EPIDEMIOLÓGICO DOS CASOS DE CERATITE NO BRASIL DE 2018 A 2022
Authors: Gomes Ferreira Filho Marcio Adriano , Fernandes de Morais Neto Joaquim , De Santana Costa Danillo , Coelho da Silva Cruz Sabryna , De Carvalho Leite Noely , Silva Luz Josué Júnior 
Published: December 2023

Introdução: A ceratite é uma inflamação da córnea, que pode ser causada por uma infecção bacteriana, viral ou fúngica, bem como por danos físicos, como hemorragia na córnea ou exposição a substâncias irritantes. Essa inflamação pode levar a uma variedade de sintomas e complicações, dependendo da gravidade do caso. Existem dois tipos principais de ceratite: ceratite infecciosa, causada por uma infecção bacteriana, viral ou fúngica Objetivos: Este estudo tem como objetivo realizar uma arguição do casos de Ceratite no Brasil de 2018 a 2022 bem como propor medidas profiláticas em relação a essa doença Metodologia: Consiste em um estudo epidemiológico de natureza descritiva, realizado por meio da coleta de dados anuais referentes ao período entre 2018 até 2022, no Brasil, disponibilizado pelo Sistema de Informações Hospitalares (SIH). As variáveis coletadas para análise epidemiológica da ceratite no Brasil incluem número de internações, ano de processamento, sexo, faixa etária, relacionadas ao capítulo IV do CID-10, especificamente na lista de morbilidade hospitalar por ceratite (CID10-H16). Resultados: Identificou-se um total de 27376 casos confirmados, com maior incidência em homens e adultos (20 a 59 anos)O Sudeste foi a região com mais notificações. Conclusão: A ceratite é uma condição ocular que pode ser causada por infecções bacterianas, virais ou fúngicas, bem como por danos físicos à córnea.
Palavras-chave: Ceratite. Córnea. Visão. Epidemiologia
PERFIL EPIDEMIOLÓGICO DAS INTERNAÇÕES POR ENDOMETRIOSE NO ESTADO DO TOCANTINS ENTRE OS ANOS DE 2011 A 2020
Authors: Cerqueira Pacheco Flávia , Parreira Vaz Guilherme , Feliciano Nunes Ribeiro Andressa , Araújo Nascimento Rodrigo , Nunes Chavante Filho Jerson , Leite Bitencourt Evandro 
Published: December 2023

INTRODUÇÃO: Endometriose é uma doença ginecológica em que há tecido endometrial externo ao útero, assintomática ou associada a sintomas, por exemplo, dor pélvica crônica, dismenorreia, infertilidade, dispareunia, queixas urinárias e intestinais. Essa doença tem repercussões socioeconômicas e culturais para a mulher e sociedade. OBJETIVO: Descrever o perfil epidemiológico das internações por endometriose de mulheres adolescentes e adultas entre os anos de 2011 a 2020 no estado do Tocantins. MÉTODO: Trata-se de um estudo epidemiológico, quantitativo e retrospectivo realizado com base nos dados disponíveis no Sistema de Morbidade Hospitalar do Sistema Único de Saúde (SIH/SUS) do Departamento de Informática do Sistema Único de Saúde (DATASUS). As características epidemiológicas das internações de mulheres na adolescência e idade adulta por endometriose foram analisadas a partir das variáveis lista de morbidades CID-10, faixa etária e cor/raça no período de 2011 a 2020 no estado do Tocantins. RESULTADOS: Houve maior incidência das internações por endometriose no estado do Tocantins nos anos de 2011 a 2020 em mulheres adultas na faixa etária entre 35 a 49 anos de idade. Os anos de 2011 a 2014 foram os que apresentaram maiores números de internações por endometriose no estado. Mulheres pardas foram predominantemente afetadas e hospitalizadas pela doença no estado, com 75,03% das internações no período analisado. CONCLUSÕES: Conclui-se que mulheres pardas e na faixa etária entre 35 e 49 anos são mais afetadas pela endometriose, com um maior número de internações. Além disso, mais estudos são necessários para compreender a epidemiologia da internação por endometriose no Tocantins e estabelecer políticas de saúde adequadas para o diagnóstico precoce e tratamento em tempo hábil da doença, com o intuito de evitar internações e suas repercussões socioeconômicas e culturais.
Palavras-chave: Endometriose; Epidemiologia; Hospitalização.
PUNÇÃO DE TIREOIDE: CORRELAÇÃO TIRADS E BETHESDA
Authors: Grando Castaldell0 Ketlyn Letícia , Claudio Teixeira João Vilson , Serapião Monica , Rodrigues da Rocha Franciani 
Published: December 2023

Introdução: A tireoide é uma glândula endócrina que está localizada na superfície anterior da traquéia, inferior à cartilagem tireóidea e profundamente aos músculos esternotireóideo e esterno-hióideo. Atua secretando os hormônios tiroxina e triiodotironina, T4 e T3, respectivamente. Objetivos: Desta forma o objetivo deste projeto é analisar e associar os achados ultrassonográficos e citopatológicos. Metodologia: Será realizado um estudo observacional, analítico, transversal e retrospectivo utilizando e realizando cruzamento dos dados de ultrassom e citopatologia de dois serviços da microrregião do Alto Vale do Itajaí. Resultados: Referente aos dados coletados sobre o sexo, foi observado que dentro da amostra analisada, 135 nódulos (87,1%) pertenciam ao sexo feminino. Em contra partida foram observados 20 nódulos sexo masculino correspondentes a 12,9%. No tocante a localidade das lesões nodulares, o lobo esquerdo foi o local anatômico da tireoide com maior prevalência de nódulos, sendo 70 (45,2%) o número encontrado, seguido pelo lobo direito, 67 nódulos (43,2%), prolongamento ístmico a esquerda 5 nódulos (3,2%), prolongamento ístmico a direita 4 nódulos (2,6%) e por fim, istmo com 3 nódulos (1,9%). Conclusão: , pode-se avaliar que os dados da coleta dos laudos realizados no período já descrito corroboram com as informações existentes em literatura, em ênfase sobre a prevalência das características nodulares, na prevalencia de sexo, sendo o feminino, além da utilidade do sistema TI-RADS como ferramenta de suporte para indicação da PAAF
Palavras-chave: Tireóide; Patologia; Ultrassom.
PENGARUH PENAMBAHAN SILIKA FUME TERHADAP KUAT TEKAN BETON
Authors: A Arman , Mulyati Mulyati , Nugroho Fajar , Fadhil Azman Hanif 
Published: December 2023

Perkembangan teknologi di Indonesia saat ini mengalami perkembangan yang cukup pesat, khususnya dalam bidang konstruksi. Beton merupakan salah satu material konstruksi yang sering digunakan pada berbagai jenis konstruksi seperti gedung, jembatan, jalan raya, bendungan dan inprastruktur sipil lainnya. Beton terdiri dari campuran material agregat kasar, agregat halus, semen, air dan kadang-kadang beton juga dapat ditambah dengan bahan kimia dan non-kimia pada perbandingan tertentu. Maka dari itu penelitian ini bertujuan untuk mengetahui pengaruh penambahan Silika fume terhadap kuat tekan beton. Pada penelitian menggunakan Silika fume dengan persentase 0%, 4%, 7%, dan 10% dari berat semen dengan 1 sampel untuk tiap persentase. Pemeriksaan sifat fisik material beton dilakukan di laboratorium Teknik Sipil ITP dan pengujian kuat tekan beton dilakukan di laboratorium Dinas PU. Penelitian ini menggunakan bahan Standar SNI 7656-2012. Benda uji yang digunakan berbentuk silinder baja dengan ukuran diameter 150 mm x tinggi 300 mm. Berdasarkan hasil uji kuat tekan beton yang dilakukan dilakukan di laboratorium Dinas PU pada umur 28 hari dari beton normal diperoleh nilai kuat tekan yaitu sebesar 27,03 Mpa, beton dengan tambahan Silika fume 4% mengalami kenaikan kuat tekan sebesar 1,59% dengan diperoleh nilai kuat tekan yaitu sebesar 27,46 Mpa, beton dengan tambahan Silika fume 7% mengalami penurunan kuat tekan sebesar 8,38% dengan diperoleh nilai kuat tekan yaitu sebesar 24,76 Mpa, dan beton dengan tambahan Silika fume 10% mengalami penurunan kuat tekan sebesar 26,89% dengan diperoleh nilai kuat tekan yaitu sebesar 19,76 Mpa. Dari data ini diketahui bahwa nilai kuat tekan optimum diperoleh pada penambahan Silika fume 4% yaitu sebesar 27,46 Mpa. Setelah melakukan penelitian ini, maka dapat disimpulkan bahwa penambahan Silika fume untuk campuran pembuatan beton dapat dilaksanakan dengan ketentuan untuk penambahan Silika Fume dibawah 4% dari berat semen.
Gene-Based Therapy for the Treatment of Spinal Muscular Atrophy Types 1 and 2
: A Systematic Review and Meta-Analysis
Authors: sanmaneechai oranee , Chongmelaxme Bunchai , Yodsurang Varalee , Vichayachaipat Ponlawat 
Published: December 2023

Abstract

Background: Despite numerous studies identifying the advantages of therapies for spinal muscular atrophy (SMA), healthcare professionals encounter obstacles in determining the most effective treatment. This study aimed to investigate the effects of gene-based therapy for SMA.
Objective :
Methods: A systematic search was conducted from inception to November 2022 across databases. All studies assessing the effects of gene-based therapy on patients with SMA types 1 and 2 were included. The outcomes measured were survival, the need for ventilatory support, improvements in motor function, and the occurrence of adverse drug reactions. Meta-analyses were performed using a random-effects model (PROSPERO registration number: CRD42021284231)
Results:A total of 42 studies (n = 1932) were included. The meta-analyses revealed that onasemnogene abeparvovec showed the highest survival rate (95% [95% CI: 88, 100]), followed by risdiplam (87% [95% CI: 77, 95]) and nusinersen (60% [95% CI: 50, 70]). The number of patients needing ventilatory support was reduced after treatment with onasemnogene abeparvovec (risk ratio = 0·10 [95% CI: 0·02, 0·53]). Onasemnogene abeparvovec and risdiplam had similar proportions of patients with improvements in the Children’s Hospital of Philadelphia Infant Test of Neuromuscular Disorders score of ≥4 points (92% [95% CI: 62, 100] vs 90% [95% CI: 77, 97]). In contrast, nusinersen had the smallest improvement (75% [95% CI: 66, 83]). The most frequently observed adverse drug reactions were headaches, vomiting, and gastrointestinal disorders.
Conclusion: Gene-based therapy benefits patient survival and improves motor function. Onasemnogene abeparvovec and risdiplam appear highly effective, whereas nusinersen exhibits moderate effectiveness.
A synchronous atmosphere-cryosphere-land response to climate on the northern Antarctic Peninsula since the mid-Holocene
Authors: Evangelista Heitor , Verkulich Sergei , Mavlyudov Bulat , Echer Mariza P. , Licinio Marcus Vinicius , Dercon Gerd , García-Rodríguez Felipe , Neto Arthur A. , Kusch Stephanie , Abuchacra Rodrigo C. , Oaquim Anna B.J. , Gonçalves Sérgio J. , Pushina Zinaida , Shimizu Marília H , Heiling Maria , Slaets Johanna , Resch Christian , Castillo Alejandra , Gruber Roman 
Published: December 2023

Abstract

West Antarctica plays a pivotal role in sea level rise in projected scenarios with global socioenvironmental and economic consequences. Therefore, describing its recent and past climate history and changes is essential for identifying the main climate controls and past responses. To better understand the climatic sensitivity of this region, we analyzed sedimentary records from newly surveyed proglacial lacustrine profiles dated from the middle Holocene to the present on the North Antarctic Peninsula. We combined atmosphere-glacier-land databases that evidenced a close coupling among these compartments during intense melting events. Our analyses furthermore suggest that a short Neoglacial phase from ∼1,500–2,000 kyr BP until the onset of the 20th century was possibly influenced by a combined long-term decline in total solar irradiance, Andean volcanism and ENSO.
Aberrant fragmentomic features of circulating cell-free mitochondrial DNA as novel biomarkers in cancer patients
Authors: Xing Jinliang , Liu Yang , Peng Fan , Wang Siyuan , Jiao Huanmin , Zhou Kaixiang , Guo Wenjie , Guo Shanshan , Zhang Huanqin 
Published: December 2023

Abstract
Fragmentomic features of circulating cell free mitochondrial DNA (ccf-mtDNA) including fragmentation profile, 5’ end base preference and motif diversity are poorly understood. Here, we generated sequencing data in 788 plasma samples and found that fragmentomic features of ccf-mtDNA were remarkably different from those of circulating cell free nuclear DNA. Furthermore, region-specific fragmentomic features were observed, which was associated with protein binding, base composition and special structure of mitochondrial DNA. Aberrant fragmentomic features were observed in six cancer types compared to non-cancer controls. Highly accurate cancer detection models were built based on the fragmentomic features. The overall accuracy of tissue-of-origin was 90.59% for six cancer types. The fragmentation profile could also be used for effective monitoring of treatment efficacy in patients with hepatocellular carcinoma. Altogether, our study comprehensively describes cancer-specific fragmentomic features of ccf-mtDNA and provides a proof-of-principle for the ccf-mtDNA fragmentomics-based cancer detection and treatment monitoring.
Nonlinear Bonding Analysis of Bolt Connection and Secondary Tightening Strategy
Authors: Qiao Yueqi , Zhao Bing , Wu Dongbo , Ouyang Weijin , Li Heng , Zhang Shen 
Published: December 2023

Abstract
The tightening process of aero-engine rotor bolt involves a nonlinear bonding stage, which poses challenges in achieving accurate control of the pre-tightening force using the way of torque control. This study proposes a secondary tightening control strategy that offers high precision and adaptability for controlling the bolt pre-tightening force based on the snug point. Firstly, we provide a detailed description of the variable stiffness process during the nonlinear bonding stage of bolt, based on theories related to bolt torque-pretension relationship and bolt deformation coordination relationship. Secondly, we design methods for extracting the snug point and calculating the target rotation angle through the Monte-Carlo simulation model and the linear goodness of fit evaluation mechanism. Thirdly, we experimentally investigate the effectiveness of this secondary tightening strategy using the typical connection section of aero-engine rotor flange bolt as our experimental object. The results indicate that applying this secondary tightening strategy can effectively mitigate uncertainties caused by nonlinear bonding and reduce errors resulting from variations in bolt characteristics and external conditions. Compared to torque control method and torque-angle control method, employing this secondary tightening strategy reduces the standard deviation of pre-tightening force from 1.875 and 1.031 to 0.536, thereby minimizing dispersion in pre-tightening force level. Additionally, it reduces maximum deviation of pre-tightening force from 30.9% and 20.1% to 2.8%, significantly enhancing accuracy in controlling bolt tightening.