bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risiko Paparan Formaldehida dari Beberapa Jenis Ikan pada Masyarakat di Kecamatan Dramaga, Bogor, Jawa Barat
Authors: Wihardi Alfin Maulana , Giriwono Puspo Edi , Indrasti Dias 
Published: October 2023

Residual formaldehyde compounds may be found in fish either naturally or intentionally added. Exposure of formaldehyde from food can cause damage to the gastrointestinal tract, liver, kidney, and is carcinogenic in humans. This study aims to estimate the risk value of formaldehyde exposure level due to fish consumption in the community population in Dramaga Subdistrict with deterministic approach. Fish consumption data was obtained from a consumption survey using a semi food frequency questionnaire (FFQ). The fish consumption survey was conducted on 505 respondents with an age range of 5-60 years and over. Formaldehyde analysis was conducted on four types of fish that are popular and often consumed by the community, namely salted peda fish, salted anchovy rice fish, salted japuh fish, and fresh anchovy fish. The results showed that formaldehyde levels in four types of fish range from 8.30 – 105.09 mg/kg. The average daily consumption of salted peda, salted anchovy rice, salted japuh, and fresh anchovy was 11.58±8.32; 8.85±4.93; 7.72±4.51; and 9.85±6.45 (g/day). The average daily exposure values of formaldehyde in salted peda, salted anchovy rice, salted japuh, and fresh anchovy were 0.0025; 0.0088; 0.0146; and 0.0014 (mg/kg bw/day). The overall of daily exposure value is still below the maximum oral exposure limit of 0.2 (mg/kg bb/day). The value of exposure risk with hazard quotient (HQ) in four types of fish is 0.007–0.073. The HQ was found to be below 1, indicating risk level of exposure to formaldehyde in the community in Dramaga Subdistrict is still within safe limits.
Kajian Numerik Sambungan Balok-Kolom Baja dengan Kuncian yang Dapat Diganti
Authors: Yuana Prima Sukma , Moestopo Muslinang , Kusumastuti Dyah , Suarjana Made 
Published: October 2023

During the Northridge and Kobe Earthquake, many steel moment resisting frames suffered damage at the beam-column connections. During these years methods were proposed by researchers which were mainly based on reducing the beam section or strengthening the connection. In this study, an innovative structural system with replaceable interlock was proposed. The main feature of this system is that plastic deformation is limited to the replaceable interlock. The monotonic test of the model using Abaqus/ Standards was carried out, compared with The Simpson Strong-Tie Strong-Frame (SSTSF) which is according to AISC 358-16 as partially restrained system with replaceable component. The analysis results demonstrated that the structural fuse and the whole structural behavior performed well. The interlock components have better strength and ductility than SSTSF. Furthermore, the replaceable interlock can play role of structural fuses by dissipating more than 86% of the input energy, which effectively protect the non-fuse components from damage.
Produksi Coconut Vinegar dari Limbah Air Kelapa dengan Model Fermentasi Cair Termodifikasi Sel Yeast Terimobilisasi Kalsium Alginat
Authors: Afifah Dini Nur , Mulyadi Abdul Haris , Fadhila Hana Syifa , Hasanah Yeti R. , Savitri Puput Wahyu Nita 
Published: October 2023

Coconut (Cocos Nucifera L) is one of the Indonesia’s plantations comodities. Unfortunately, the abundance of raw materials has not had a significant impact on the export market for coconut products, especially functional food products. Based on that issue, research with the aim to produce diversified product of coconut was conducted. The product developed in this research was coconut vinegar produced by fermentation process of coconut waste water via liquid fermentation pathway. To increase efficiency and reduce production costs, the fermentation process was carried out simultaneously. In order to increase the yeast resistance to acetic acid produced by acetic acid bacteria (BAA), the process modification was conducted by using yeast immobilized formed by the calcium alginate matrix. The research results show that the optimum BAA inoculation time was 24 hours after the bead yeast inoculation. The maximum bead yeast mass obtained in this study was 25% m/v. Fermentation that was carried out with the maximum time and bead mass was able to produce coconut vinegar with an acetic acid content of 5.1 g/L, an alcohol conversion of 22.73%.
This work is licensed under a Creative Commons Attribution 4.0 International License
Mediasi regulasi diri atas pengaruh lingkungan belajar terhadap hasil belajar matematika Siswa SMP
Authors: Abbas Abdul Basir , Rizki Nanda Arista 
Published: October 2023

Penelitian ini menyelidiki pengaruh lingkungan belajar terhadap hasil belajar matematika Siswa, di semester 2 kelas VIII SMP Negeri Samarinda Ulu tahun ajaran 2022, dan juga menyelidiki apakah variabel regulasi diri merupakan mediasi dari pengaruh tersebut. Pengumpulan data dengan kuesioner dan tes hasil belajar diterapkan terhadap 380 Siswa dari 4 lembaga sekolah negeri jenjang SMP, yang diperoleh melalui Proportional Cluster Random Sampling. Pemodelan persamaan struktural diterapkan, yang didahului dengan analisis faktor konfirmasi untuk memantapkan pengukuran bagi tiga variabel yang diteliti. Hasil menunjukan bahwa lingkungan belajar berpengaruh signifikan terhadap hasil belajar matematika Siswa, dengan regulasi diri sebagai mediasi parsial.
Some aspects of nasopharyngeal microflora in children with psoriasis
Authors: Murzina E.О. , Litus O.І. , Vozianova S.V. , Bardova K.O. , Patselia M.V. , Yavorovska O.O. 
Published: October 2023

Objective — to study the state of nasopharyngeal microflora in children with psoriasis depending on the clinical features of dermatosis and determine antibiotic susceptibility of isolated microorganisms.
Materials and methods. The isolation of nasopharyngeal microorganisms and determination of their antibiotic susceptibility were performed in 57 children with psoriasis aged 4 to 17 using the bacteriological method (culture). Microbial growth was assessed according to four degrees of growth. Susceptibility to antibacterial drugs was evaluated based on the following criteria: sensitive, moderately resistant, and resistant. Study materials were statistically processed using the StatTech v. 3.1 software.
Results and discussion. Most often, Staphylococcus aureus (S. aureus) associations were cultured from the nasopharynx (56.15 %) of children with psoriasis — in 12.28 % of cases, Enterococcus faecium (Ent. faecium) — in 21.05 %. Statistically significant differences in children with psoriasis were found between the colony growth rates of Ent. faecium and S. aureus (p < 0.001): massive microbial growth of Ent. faecium prevailed (64.91 %), and S. aureus was not isolated at all in the majority of children (29.82 %). Ent. faecium growth rates were statistically significantly different (p = 0.016) depending on psoriasis severity according to PASI: massive growth of microorganisms at PASI > 10 was found in 87.5 % of cases, and at PASI ≤ 10 — in 54.2 % of cases. The proportion of Ent. faecium resistant to antimicrobial drugs (43.18 ± 7.47) % was found to be more than two times higher than that of S. aureus (20.00 ± 6.32) %. The susceptibility testing for each microorganism individually showed that enterococci were 28 to 100 % susceptible to antibacterial drugs, while staphylococci had 42 to 100 % susceptibility. Statistically significant differences were found between the percentage of sensitivity of Ent. faecium to antibacterial drugs between the group of children with the first diagnosis of psoriasis and the group of children with its recurrences (p = 0.005), as well as by the duration of the disease (p < 0.001).
Conclusions. The results of the study of children with psoriasis showed that there were bacterial associations isolated from the nasopharynx in the most significant number of cases with the predominance of Ent. faecium, which had massive growth in almost 65 % of cases and affected psoriasis severity according to PASI (OR 5.923; 95 % CI 1.387—25.300). The proportion of Ent. faecium resistant to antibiotics was higher than of S. aureus (p < 0.05), but with increasing duration of psoriasis, Ent. faecium susceptibility to antimicrobials increased (r = 0.439; p = 0.004). In general, S. aureus isolated from the nasopharynx of children with psoriasis had more pronounced antibiotic susceptibility than Ent. faecium.
SUBSTANTIATION OF THE STRENGTH OF THE CAR BODY BEARING STRUCTURE TAKING INTO ACCOUNT CRITICAL STRESSES IN FLUTES
Authors: Sorokina Elena , Korshunov Sergey , Goncharov Dmitriy , Zhukov Aleksandr 
Published: October 2023

The issues are considered that are connected with substantiating the strength and stability of the metal structure of a double-deck passenger car body under the influence of both compressive loads and the effects of excessive solar radiation and other external factors.
A computational and experimental method is proposed for assessing the stability of corrugated sections of the roof slopes of passenger car bodies. Five variants of the structural design of the double-deck car roof covering are proposed. The stability of the covering for the accepted variants was evaluated by an analytical method using a tabular and rod finite element model. Based on the results of the calculation, a rational variant of the structural design of the car roof was determined.
The results of theoretical studies are confirmed by the data of full-scale bench tests of the metal structure of a new double-deck car body.
NATO Expansion to the East: Georgia’s Way to NATO Membership, Perspectives and Challenges
Authors: Kavadze Amiran , Kavadze Tina 
Published: October 2023

The article explores possible NATO enlargement to the East. The study is based on case study analyses and has two objectives:to provide analyses of the dynamics of Georgia’s Euro-Atlantic process, and to show how this process corresponds toexisting experience and practice. Georgia’s Euro-Atlantic aspirations, integration path, and domestic and external factors have all been taken into consideration, as have the degree to which Russia can negatively influence the eastward enlargement process, and what candidate/aspirant countries can offer NATO to secure future membership. The authors present scenarios that are likely to affect domestic and international changes with regard to future NATO membership.
The Origins of the Second Gulf War
Authors: Kikalishvili Shalva 
Published: October 2023

leading up to the Second Gulf War. Using declassified and historical documents, this paper examines the influential role of those neo-conservatives and war lobbyists who strongly influenced George W. Bush in the planning, strategizing, and later launching of “Operation Iraqi Freedom.” The paper highlights the author’s perspective on the Second Persian Gulf War. It is based on the research conducted through analysis and discussion of existing political documents and various standpoint theories of some historians. The objective is to create a vivid picture of the US Government Plans towards Iraq and the involvementof war lobbyists and major decision-makers in this process during the Presidency of George W. Bush. The sole aim of the article is to describe and analyze US Foreign policy in connection with Iraq before the Second Gulf War, as the topic has not been explored in depth yet and is still open for discussion due to present day situation in Iraq.
Transnational Security of South Caucasus
Authors: TSKHOVREBADZE Tamta 
Published: October 2023

Despite of occupying a comparatively small territory, The South Caucasus exhibit a bizarre cultural, religious, linguistic, ethnical diversity. The region is squeezed between Caspian and Black Seas, comprising the states of Armenia, Azerbaijan and Georgia. Region has considerable interest from the global players of international politics since it occupies a key strategic location and frames a bridge between Asia and Europe through linking the Caspian Sea and Central Asia with the Black Sea and Western Europe. Furthermore, South Caucasus is an important transport and energy corridor, notably as a hydrocarbons transit route from Caspian Sea region to international markets.This paper examines general view of security architecture in South Caucasus with the aim of emphasizing most prominent security challenges and threats. It also assesses the transnational security challenges that the region faces, demonstrating the lack of regional cooperation and considers the potential for cooperation in the future. The central research question here is what are the most prominent transnational threats for the region and how can these threats be addressed? Is there enough individual effort for South Caucasian States to eliminate the threats or a basis for broader cooperation and efforts to collective security should be formed?
International Society
Authors: MKALAVISHVILI Tamar 
Published: October 2023

The article focuses on explaining the importance of having the International Society. Main positive aspects are indicated with the citations of Scientifics. Modern International Society is the firstling of European International Society. It was found in the Europe state system and with the spread of European culture, juridical norms and rules, it gained the global dimension. Nowadays, International society is in the developing process, so my thesis suggests you the possible variations how the international society might be in future.
Characteristics of Initiating Criminal Prosecution in England and France
Authors: MEURMISHVILI Besik 
Published: October 2023

The given article concerns the characteristics of initiating criminal prosecution in England and France. Besides that, discussionsare held in the comparative legal context about initiating criminal prosecution in Georgia, France and England. Based on the comparison of procedural provisions of these countries the similarities and differences of initiating criminal prosecution have been distinguished. Furthermore, the article focuses on the range of bodies having an authority to initiate the prosecution. In the final part an evaluation is made whether it is appropriate to consider the elements of initiating prosecution of England andFrance in the criminal procedure law of Georgia.
Where is the Boundary between Freedom of Expression and a Person’s Honor, Dignity and Business Reputation - Some Examples from the Georgian Court Practice
Authors: LAKERBAIA Tamar 
Published: October 2023

Media law is a relatively new trend in the field of law, the importance of which is growing rapidly. The civilized world unanimously recognized the freedom of the press as the foundation of a democratic society. Equal importance is to ensure freedom of speech and expression as eternal and supreme human values and provide appropriate standards for their implementation. However, like most of the fundamental rights, freedom of expression is not absolute. It can be restricted, if it is necessary to protect the rights and dignity of others. The purpose of this paper is to examine the general legal principles of freedom of expression in Georgia and analysis of judicial practice in this area. Of particular importance is the conflict between the values between freedom of expression and the protection of honor and dignity of others. Specifically, the issue is where the boundary between these two fundamental rights.
APLIKASI PENCATATAN KELUAR MASUK BUKU TANAH DAN SURAT UKUR PADA KANTOR PERTANAHAN KABUPATEN PRINGSEWU BERBASIS ANDROID
Authors: Martin Afrizal , , Mardiyanto , , Widianto 
Published: October 2023

Pada era perkembangan teknologi yang semakin berkembang khususnya pada dunia kerja yaitu perkantoran. Banyak hal yang dapat di inovasikan dalam dunia kerja salah satunya yaitu memanfaatkan IT. Dalam hal ini terdapat beberapa kantor yang masih belum memanfaatkan IT, salah satu nya yaitu kantor pertanahan kabupaten pringsewu dimana dalam hal ini terdapat beberapa bagian atau seksi yang masih belum menerapkan IT yaitu bagian arsip, dimana dalam sistem pencatatan buku tanah dan surat ukur masih menggunakan sistem manual melalui buku besar. untuk mempermudah dan membantu petugas arsip dalam meningkatkan kinerja, maka dari itu dibuatnya penelitian ini aplikasi pencatatan keluar masuk buku tanah dan surat ukur menggunakan Mit App Inventor. Penelitian ini didukung melalui metode System Development Life Cycle (SDLC). Hasil dari pada penelitian ini yaitu berupa aplikasi yang dapat di implementasikan sesuai dengan kebutuhan.
DESAIN DAN IMPLEMENTASI ALAT UKUR UNSUR HARA TANAH MENGGUNAKAN SENSOR NPK BERBASIS WIRELESS SENSOR NETWORK (WSN)
Authors: Ratna Silvia , , Arafat , , Wagino 
Published: October 2023

Wireless Sensor Network (WSN) digunakan untuk melakukan pengambilan data pada parameter ukur dengan menggunakan sekumpulan sensor dan kemudian dikirimkan pada sebuah server untuk dilakukan pengolahan data. Pada penelitian ini menggunakan 2 buah lahan pertanian di tempat yang berbeda, dan akan di monitoring dengan dashboard thingsboard. Tanah merupakan media yang paling penting bagi pertumbuhan tanaman. Tujuan dari penelitian ini adalah untuk mengembangkan sistem deteksi unsur hara utama tanah; Nitrogen, Fosfor dan Kalium (NPK) yang terdiri dari sensor NPK.Media tanam yang cocok adalah media tanah yang memiliki kualitas baik yang dapat mendukung pertumbuhan tanaman dengan cepat. Tanah yang subur merupakan kebutuhan primer bagi tanaman. Kualitas media tanam sangat mempengaruhi pada pertumbuhan tanaman. Jenis tanah yang dibutuhkan untuk pertumbuhan tanaman bermacam-macam, yaitu tanah berpasir, tanah merah, tanah hitam, tanah gambut, dan tanah humus.Sensor NPK yang berfungsi untuk mendeteksi unsur hara dalam tanah dan dapat bekerja jika ujung sensor tersebut ditancapkan ke dalam tanah yang ingin dideteksi, hasilnya terdeteksi oleh sensor akan dikirimkan berupa data sinyal analog ke esp32, yang akan diproses dan ditampilkan di layar oled LCD dan di dashboard thingsboard. Alat ini dikendalikan oleh esp32 dengan sensor NPK untuk mendeteksi kadar nutrisi dalam tanah dengan output ke oled LCD dan thingsboard.Kata kunci : WSN, esp32, NPK, thingsboard, unsur hara
Legislasi dan Kebijakan Negara di Tengah Pandemi
Authors: Andriani Henny 
Published: October 2023

Artikel ini berusaha menjelaskan bahwa konstitusi telah memberikan ruang konstitusional dalam menghadapi kondisi darurat. Besarnya kekuasaan yang diberikan oleh konstitusi kepada negara di tengah keadaan darurat menimbulkan sejumlah kekhawatiran masyarakat tentang pelanggaran dan penyalahgunaan kekuasaan. Pelanggaran dan penyalahgunaan kekuasaan ini dapat dilacak melalui sejumlah potret problematika pembentukan peraturan perundang-undangan dan kebijakan yang lahir pada masa pandemi. Perundang-undangan dan kebijakan negara yang dibentuk pada masa pandemi tidak terlepas dari berbagai konflik dan menuai kritik keras diruang publik. Mulai dari kebijakan yang dianggap tidak responsif dan tidak fokus dalam menangani wabah Covid-19. Hingga memiliki cacat material dan formal dalam proses pembentukannya. Pasalnya, meski konstitusi telah memberikan ruang konstitusional dalam menghadapi kondisi darurat, Pemerintah belum mampu menangani wabah ini secara efektif dan signifikan, ditambah dengan kewenangan yang cukup besar yang diberikan konstitusi kepada negara di tengah keadaan darurat. Hal itu menimbulkan sejumlah kekhawatiran publik tentang pelanggaran dan penyalahgunaan kekuasaan. Oleh karena itu, penelitian ini mengkaji dan mendeskripsikan apa saja permasalahan peraturan perundang-undangan negara selama masa pandemi Covid-19 yang menjadi problematika dan mencoba menjelaskan bagaimana seharusnya negara membuat kebijakan di tengah keadaan darurat.
CYFRA 21-1, CA 125 and CEA provide additional prognostic value in NSCLC patients with stable disease at first CT scan
Authors: Muley Thomas , Schneider Mark A. , Meister Michael , Thomas Michael , Heußel Claus Peter , Kriegsmann Mark , Holdenrieder Stefan , Wehnl Birgit , Rolny Vinzent , Mang Anika , Gerber Rebecca , Herth Felix 
Published: October 2023

BACKGROUND: Serum tumor markers (STM) may complement imaging and provide additional clinical information for patients with non-small cell lung cancer (NSCLC). OBJECTIVE: To determine whether STMs can predict outcomes in patients with stable disease (SD) after initial treatment. METHODS: This single-center, prospective, observational trial enrolled 395 patients with stage III/IV treatment-naïve NSCLC; of which 263 patients were included in this analysis. Computed Tomography (CT) scans were performed and STMs measured before and after initial treatment (two cycles of chemotherapy and/or an immune checkpoint inhibitor or tyrosine kinase inhibitor); analyses were based on CT and STM measurements obtained at first CT performed after cycle 2 only PFS and OS were analyzed by Kaplan-Meier curves and Cox-proportional hazard models. RESULTS: When patients with SD ( n = 100) were split into high- and low-risk groups based on CYFRA 21-1, CEA and CA 125 measurements using an optimized cut-off, a 4-fold increase risk of progression or death was estimated for high- vs low-risk SD patients (PFS, HR 4.17; OS, 3.99; both p < 0.0001). Outcomes were similar between patients with high-risk SD or progressive disease ( n = 35) (OS, HR 1.17) and between patients with low-risk SD or partial response ( n = 128) (PFS, HR 0.98; OS, 1.14). CONCLUSIONS: STMs can provide further guidance in patients with indeterminate CT responses by separating them into high- and low-risk groups for future PFS and OS events.
Prognostic value of tumor markers ProGRP, NSE and CYFRA 21-1 in patients with small cell lung cancer and chemotherapy-induced remission
Authors: Muley Thomas , Herth Felix J. , Heussel Claus Peter , Kriegsmann Mark , Thomas Michael , Meister Michael , Schneider Marc A. , Wehnl Birgit , Mang Anika , Holdenrieder Stefan 
Published: October 2023

BACKGROUND: Despite successful response to first line therapy, patients with small-cell lung cancer (SCLC) often suffer from early relapses and disease progression. OBJECTIVE: To investigate the relevance of serum tumor markers for estimation of prognosis at several time points during the course of disease. METHODS: In a prospective, single-center study, serial assessments of progastrin-releasing peptide (ProGRP), neuron-specific enolase (NSE), cytokeratin-19 fragments (CYFRA 21-1) and carcino-embryogenic antigen (CEA) were performed during and after chemotherapy in 232 SCLC patients, and correlated with therapy response and overall survival (OS). RESULTS: ProGRP, NSE and CYFRA 21-1 levels decreased quickly after the first chemotherapy cycle and correlated well with the radiological response. Either as single markers or in combination they provided valuable prognostic information regarding OS at all timepoints investigated: prior to first-line therapy, after two treatment cycles in patients with successful response to first-line therapy, and prior to the start of second-line therapy. Furthermore, they were useful for continuous monitoring during and after therapy and often indicated progressive disease several months ahead of radiological changes. CONCLUSIONS: The results indicate the great potential of ProGRP, NSE and CYFRA 21-1 for estimating prognosis and monitoring of SCLC patients throughout the course of the disease.