bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prevalence of pelvic floor dysfunction and associated risk factors among Nulligravida college students: a cross-sectional study
Authors: Aiyegbusi Ayoola Ibifubara , Eze Desire Ifeoma , Balogun Oluwaseyi Jessy , Olamijulo Joseph Ayodeji 
Published: October 2023

Abstract
Background
Pelvic floor dysfunction (PFD) is a global health problem affecting millions of women worldwide. Vaginal childbirth has been reported to be the most important factor in the etiology of PFD though a prior study also reported a high prevalence of PFD in nulliparous women. Some previous studies had suggested Urinary incontinence before pregnancy as a major risk factor for incontinence later in life, thus prevention of PFD has become a major priority in women’s health, and identification of women at risk is a key element in current prevention strategies It is therefore necessary to investigate the prevalence and risk factors for PFD in Nulligravida women who have never been pregnant to enable preventative measures especially as it regards lifestyle modification.

Methods
Participants were 160 Nulligravida students aged between 17 and 26 years. They were screened for pelvic floor dysfunction using an Australian pelvic floor questionnaire which assessed their bladder function, bowel function, pelvic organ prolapse, and sexual function. Descriptive statistics of frequency and percentage were used to summarize categorical variables. Univariate analysis of Fisher’s exact test and Wilcoxon rank-sum test were conducted to show the association of categorical and continuous variables with pelvic floor dysfunction (PFD) respectively. The risk factors of PFD with p values < 0.05 were considered significant. All analyses were performed using R Statistical Computing Programming version 4.2.2.

Results
The prevalence of having at least one of any of the PFD was 73.1% while the prevalence of bladder, bowel, prolapse, and sex dysfunction were 25.63% (41/160), 53.75% (86/160), 1.88% (3/160), and 23.13% (37/160) respectively. BMI was not a significant risk factor for any type of PFD while multi-variable logistic regression identified the level of study, height, history of UTI, and non-sport participation as significant (p < 0.05) risk factors for at least one type of PFD with Odd ratio of 4.91, > 100, 8.47, and 2.86 respectively.

Conclusion
There is high prevalence of PFD among Nulligravida students, with non-participation in sports and history of urinary tract infections being the main significant risk factors.
Dehydroepiandrosterone sulfate to cortisol ratio as a prognostic factor in cirrhotic patients with spontaneous bacterial peritonitis
Authors: Asker Mohamed Ramadan , Elahwal Loai Mohamed , Hazzaa Sahar Mohy-Eldin , Elhoseeny Shireen Ali , Sarhan Mohamed Elsayed 
Published: October 2023

Abstract
Background
Chronic liver disease and decompensated cirrhosis are associated with serious complications; spontaneous bacterial peritonitis is considered one of them that may lead to sepsis and adrenal insufficiency. This trial aimed to study the role of dehydroepiandrosterone sulfate (DHEAS) and DHEAS/cortisol ratio for assessing cirrhotic patients’ adrenal function and as a possible prognostic factor in cirrhotic cases with spontaneous bacterial peritonitis (SBP).

Patients and methods
It was a prospective cohort trial carried out on 100 patients in the Internal Medicine Department, Tanta University Hospital, from June 2021 to July 2022 divided into 2 studied patient groups: group I, 50 cases with liver cirrhosis and sterile ascites; and group II, 50 cases with liver cirrhosis and SBP. Adrenal function was evaluated using serum cortisol levels (9 A.M, 9 P.M, and post synacthen stimulation test), DHEAS level, and DHEAS/cortisol ratio.

Results
The cirrhotic patients with SBP have significantly decreased DHEAS, decreased DHEAS/cortisol ratio, and high cortisol level post stimulation compared with patients with sterile ascites, cirrhotic cases with decreased DHEAS/cortisol ratio (< 0.65) had elevated C-reactive protein (CRP) levels, a higher model for end-stage liver disease (MELD) score and Child–Pugh score had higher hospital mortality. Both DHEAS and the DHEAS/cortisol ratio were significant predictors of hospital mortality (area under the receiver operating characteristic curve 0.267 and 0.298, respectively). The cirrhotic patients with SBP had decreased DHEAS and DHEAS/cortisol ratio but higher hospital mortality, compared to the cirrhotic patients with sterile ascites.

Conclusions
It was found that a significant increase in cortisol level was after synacthen stimulation, decreased DHEAS, and low DHEAS to cortisol ratio in the cirrhotic patients with spontaneous bacterial peritonitis and was associated with high mortality compared to cirrhotic patients without spontaneous bacterial peritonitis.
Deciphering the Clinical Presentations in LMNA-related Lipodystrophy: Report of 115 Cases and a Systematic Review
Authors: Besci Ozge , Foss de Freitas Maria Christina , Guidorizzi Natália Rossin , Guler Merve Celik , Gilio Donatella , Maung Jessica N , Schill Rebecca L , Hoose Keegan S , Obua Bonje N , Gomes Anabela D , Yıldırım Şimşir Ilgın , Demir Korcan , Akinci Baris , MacDougald Ormond A , Oral Elif A 
Published: October 2023

Abstract

Context
Lipodystrophy syndromes are a heterogeneous group of rare genetic or acquired disorders characterized by generalized or partial loss of adipose tissue. LMNA-related lipodystrophy syndromes are classified based on the severity and distribution of adipose tissue loss.

Objective
We aimed to annotate all clinical and metabolic features of patients with lipodystrophy syndromes carrying pathogenic LMNA variants and assess potential genotype-phenotype relationships.

Methods
We retrospectively reviewed and analyzed all our cases (n = 115) and all published cases (n = 379) curated from 94 studies in the literature.

Results
The study included 494 patients. The most common variants in our study, R482Q and R482W, were associated with similar metabolic characteristics and complications though those with the R482W variant were younger (aged 33 [24] years vs 44 [25] years; P &lt; .001), had an earlier diabetes diagnosis (aged 27 [18] vs 40 [17] years; P &lt; .001) and had lower body mass index levels (24 [5] vs 25 [4]; P = .037). Dyslipidemia was the earliest biochemical evidence described in 83% of all patients at a median age of 26 (10) years, while diabetes was reported in 61% of cases. Among 39 patients with an episode of acute pancreatitis, the median age at acute pancreatitis diagnosis was 20 (17) years. Patients who were reported to have diabetes had 3.2 times, while those with hypertriglyceridemia had 12.0 times, the odds of having pancreatitis compared to those who did not.

Conclusion
This study reports the largest number of patients with LMNA-related lipodystrophy syndromes to date. Our report helps to quantify the prevalence of the known and rare complications associated with different phenotypes and serves as a comprehensive catalog of all known cases.
Vertebral Body Reshaping after Fractures: An Important Index of Recovery in Glucocorticoid-Treated Children
Authors: Ma Jinhui , Siminoski Kerry , Jaremko Jacob L , Koujok Khaldoun , Matzinger Mary Ann , Shenouda Nazih , Wilson Nagwa , Cheng Megan , Alos Nathalie , Atkinson Stephanie , Cummings Elizabeth A , Ho Josephine , Rodd Celia , Sbrocchi Anne Marie , Stein Robert , Barr Ronald , Cairney Elizabeth , Dix David B , Fernandez Conrad V , Grant Ronald , Halton Jacqueline , Israels Sara , Laverdière Caroline , Lewis Victor A , Cabral David A , Huber Adam , Houghton Kristin , Jurencak Roman , Lang Bianca , Larché Maggie , LeBlanc Claire M A , Miettunen Paivi , Roth Johannes , Scuccimarri Rosie , Bell Lorraine , Blydt-Hansen Tom , Filler Guido , Feber Janusz , Phan Véronique , Smit Kevin , Rauch Frank , Ward Leanne M 
Published: October 2023

Abstract

Purpose
In this 6-year study we identified factors associated with spontaneous vertebral body reshaping in glucocorticoid (GC)-treated children with leukemia, rheumatic disorders, and nephrotic syndrome.

Methods
Subjects were 79 children (mean age 7.4 years) who had vertebral fracture (VF) evaluation on lateral spine radiographs at least 1 year after VF detection. VF were graded using the modified Genant semiquantitative method and fracture burden for individuals was quantified using the spinal deformity index (SDI; sum of grades from T4 to L4).

Results
Sixty-five children (82.3%) underwent complete vertebral body reshaping (median time from VF detection to complete reshaping 1.3 years by Cox proportional hazard modeling). Of 237 VF, the majority (83.1%) ultimately reshaped, with 87.2% reshaping in the thoracic region vs 70.7% in the lumbar region (P = .004). Cox models showed that (1) every g/m2 increase in GC exposure in the first year after VF detection was associated with a 19% decline in the probability of reshaping; (2) each unit increase in the SDI at the time of VF detection was associated with a 19% decline in the probability of reshaping [hazard ratio (HR) = 0.81; 95% confidence interval (CI) = 0.71, 0.92; P = .001]; (3) each additional VF present at the time of VF detection reduced reshaping by 25% (HR = 0.75; 95% CI = 0.62, 0.90; P = .002); and (4) each higher grade of VF severity decreased reshaping by 65% (HR = 0.35; 95% CI = 0.21, 0.57; P &lt; .001).

Conclusion
After experiencing a VF, children with higher GC exposure, higher SDI, more severe fractures, or lumbar VF were at increased risk for persistent vertebral deformity.
yes. still. movement.
Authors: McQuirter Marya 
Published: October 2023

Abstract
How does one attempt to look at a photograph that is not attached to an institutional archive and for which there is no known historical data? How does one attempt to look when all you have is the photographic object? Focusing on a circa 1893 tintype of a couple of bicyclists taken at an indoor photography studio, this essay offers a set of reading practices that position photographic subjects as coproducers with the photographer and argues for stillness as a form of movement, rather than the suspension of movement. Conceived this way, this stillness illuminates the connections between movement indoors and outdoors and imagines nineteenth century US-based photographic subjects as diasporic cultural producers. The tintype is part of a larger set of what this essay calls bicycling photographs that were popular in the late nineteenth century, through which individuals and groups remixed two of the most popular technologies — bicycles and photography — to create new material objects that they could frame and keep in a dwelling place and move within and between dwelling places. Moreover, through the coproduction of new material objects, the duo, and many others, gave themselves other mobile lives.
Malarstwo w Krośnie w pierwszej połowie XVI wieku – addenda
Authors: Łopatkiewicz Piotr 
Published: October 2023

Malarstwo w Krośnie w pierwszej połowie XVI wieku – addenda
W roku 2007 ukazała się książka Piotra Łopatkiewicza Malarstwo w Krośnie w pierwszej połowie XVI wieku, stanowiąca dysertację doktorską autora przygotowaną w 2003 roku, w Instytucie Historii Sztuki UJ. W pracy tej przedstawiono kilkadziesiąt dzieł malarstwa tablicowego i monumentalnego oraz podjęto próbę powiązania ich z krośnieńskim środowiskiem artystycznym. Analiza i charakterystyka materiału zabytkowego, uwzględniająca tematykę dzieł, pozwoliła na rekonstrukcję rozproszonych nastaw ołtarzowych, omówienie ich genezy artystycznej i pierwotnego miejsca przeznaczenia, w końcu zaś – wyodrębnienie kilku grup dzieł malarstwa, łączących się z konkretnymi warsztatami. Co ważne w kilku przypadkach – po raz pierwszy – możliwe okazało się powiązanie dzieł z imionami czynnych w Krośnie malarzy.
Ujawnienie na przestrzeni ostatnich 20 lat, kilku ważnych zabytków malarstwa tablicowego (Krosno, Kombornia, Warzyce) i monumentalnego (Krosno, Domaradz), skłoniły autora do zaprezentowania zarówno wyników prac badawczych prowadzonych w ostatnim czasie, jak i podjęcia próby powiązania ujawnionych dzieł malarstwa z wyodrębnionymi wcześniej grupami warsztatowymi. Przedstawione wyniki badań dowodzą, iż w dziedzinie malarstwa średniowiecznego tego regionu czas odkryć wciąż jeszcze się nie zakończył, a każde nowe odkrycie, poszerzając zasób znanych dzieł malarskich, skutkować będzie w przyszłości koniecznością dopisywania kolejnych addend.
Podkarpacie 1944 oczami sowieckiego szeregowca. O prozie wojennej i wspomnieniowej Wiktora Astafiewa
Authors: Wawrzyńczak Aleksander 
Published: October 2023

Podkarpacie 1944 oczami sowieckiego szeregowca. O prozie wojennej i wspomnieniowej Wiktora Astafiewa
Wiktor Astafiew, wybitny pisarz rosyjski, drugiej połowy XX wieku, reprezentant prozy wiejskiej, jako uczestnik II wojny światowej, wiele miejsca w swojej twórczości poświęcił tematyce wojennej. Wraz z Armią Czerwoną walczył też w Polsce na Podkarpaciu. Artykuł prezentuje obraz Podkarpacia w prozie wojennej i wspomnieniowej rosyjskiego prozaika. Z jednej strony Astafiew nie kryje swojej fascynacji polską kulturą szlachecką i pejzażami Podkarpacia, z drugiej zaś w jego relacjach widoczny jest wpływ radzieckiej historiografii i propagandy. Pomimo ewolucji twórczej i światopoglądowej – odrzucenia komunizmu i potępienia wszelkich wojen – pisarz nie potrafił pogodzić się z polską narracją historyczną po 1989 roku, w której Armia Czerwona straciła status „wyzwoliciela” ziem polskich spod niemieckiej okupacji. To stało się przyczyną zmiany stosunku do Polaków, wobec których w swojej ostatniej powieści Wesoły żołnierz Astafiew zajął postawę nader krytyczną.
Klimow i inni. O niezrealizowanych ekranizacjach „Mistrza i Małgorzaty”
Authors: Przebinda Igor 
Published: October 2023

Klimow i inni. O niezrealizowanych ekranizacjach „Mistrza i Małgorzaty”
W niniejszym artykule podjęto próbę zarysowania historii najważniejszych planowanych, lecz ostatecznie niezrealizowanych ekranizacji Mistrza i Małgorzaty. Omówione projekty obejmują okres około pięćdziesięciu lat i rozciągają się w czasie od późnych lat 60. XX w. do lat 20. XXI w. Opisywane przedsięwzięcia filmowe planowane były głównie w wytwórniach radzieckich (Mosfilm) i rosyjskich (Mars Media) oraz w studiach hollywoodzkich (m.in. Columbia i Lucasfilm), przy udziale twórców rosyjskich, amerykańskich i europejskich. Artykuł skupia się w dużej części na szkicowaniu obrazu konkretnych działań projektowych i producenckich w obrębie tychże przedsięwzięć. Osobne miejsce poświęcone jest adaptacyjnym strategiom adaptacyjnym, ze szczególnym uwzględnieniem scenariusza braci Klimowów.
Detection and classification of radial carpet beams propagating through an underwater medium
Authors: Khodadadi Karahroudi Mahdi , JafarFard Mohammad Reza 
Published: October 2023

A radial carpet (RC) optical beam is a type of structured light beam that is classified as a subfamily of combined half-integer Bessel-like beams. Coherent detection of such structured modes can be difficult given their structural complexity and the deterioration of the quality of modes during propagation in turbulent environments. In this paper, we first study the detection of RC modes by using fork-shaped diffraction gratings and then propose an incoherent detection approach to classify 16 classes of RC modes based on training a convolutional neural network model using DenseNet-201 architecture. The dataset comprises recorded images of RC modes after a 120 cm propagation length in a turbulent underwater environment. As the evaluations indicate, the classifier has an accuracy of 98% in identifying RC modes measured in moderate turbulence with a strength level of C
n
2∼10−12m−2/3. This method eliminates the difficulties caused by the use of multiple optical elements in coherent detection techniques such as diffraction gratings. Besides simplifying the optical system settings, it also reduces the volume and cost of implementation, especially in optical communication applications.
Fano resonance-enhanced Si/MoS2 photodetector
Authors: Gong Tianxun , Yan Boyuan , Zhang Taiping , Huang Wen , He Yuhao , Xu Xiaoyu , Sun Song , Zhang Xiaosheng 
Published: October 2023

In this work, a Si/MoS2 heterojunction photodetector enhanced by hot electron injection through Fano resonance is developed. By preparing Au oligomers using capillary-assisted particle assembly (CAPA) on the silicon substrate with a nanohole array and covering few-layer MoS2 with Au electrodes on top of the oligomer structures, the Fano resonance couples with a Si/MoS2 heterojunction. With on-resonance excitation, Fano resonance generated many hot electrons on the surface of oligomers, and the hot electrons were injected into MoS2, providing an increased current in the photodetector under a bias voltage. The photodetectors exhibited a broadband photoresponse ranging from 450 to 1064 nm, and a large responsivity up to 52 A/W at a wavelength of 785 nm under a bias voltage of 3 V. The demonstrated Fano resonance-enhanced Si/MoS2 heterojunction photodetector provides a strategy to improve the photoresponsivity of two-dimensional materials-based photodetectors for optoelectronic applications in the field of visible and near-infrared detection.
Schistosoma haematobium infection and morbidity risk factors for pre-school age children in western Angola: A knowledge, attitudes and practices survey
Authors: Sánchez-Marqués Raquel , Salvador Fernando , Bocanegra Cristina , Nindia Arlette , Pintar Zeferino , Martínez Joan , Aixut Sandra , Pessela Agostinho , Ramírez-Arroyo Sheila , Farrés Aina , Chopo María , Izquierdo Silvia , Mas-Coma Santiago , Bargues María Dolores , Molina Israel 
Published: October 2023

Background
Urogenital schistosomiasis is one of the most prevalent parasitic diseases in sub-Saharan Africa. It is a poverty-related disease conditioned by behavioural practices.

Methods
Our objective is to evaluate the awareness, mindset and habits about urogenital schistosomiasis in the community of Cubal (Angola), as well as its association with infection and urinary tract morbidity in pre-school age children. A cross-sectional study of knowledge, attitudes and practices at home was conducted between February and May 2022 with 250 participants.

Results
Overall, 93.6% of those surveyed had some prior knowledge about schistosomiasis and, among all the symptoms associated with this disease, blood in the urine was the best known (54.4%). Nevertheless, 57.6% obtained a medium knowledge score. Regarding attitude, the majority of respondents had a high attitude score (79.2%) with 96.0% willing to participate in mass drug administration campaigns. Laundry in the river was the most common risk practice (61.2%) and 55.2% out of the total were classified with a low practice score.

Conclusion
Low knowledge about symptoms and transmission by caregivers was the outstanding risk factor for infection in pre-school age children (OR = 16.93, 95%CI: 3.93–72.82), and lack of knowledge that avoiding entering the river prevents schistosomiasis was the main risk factor for morbidity in PSAC (OR = 8.14, 95%CI: 1.14–58.25).
Competing-risks model for predicting the prognostic value of lymph nodes in medullary thyroid carcinoma
Authors: Shang Fangjian , Liu Xiaodan , Ren Xin , Li Yanlin , Cai Lei , Sun Yujia , Wen Jian , Zhai Xiaodan 
Published: October 2023

Background
Medullary thyroid carcinoma (MTC) is an infrequent form malignant tumor with a poor prognosis. Because of the influence of competitive risk, there may suffer from bias in the analysis of prognostic factors of MTC.

Methods
By extracting the data of patients diagnosed with MTC registered in the Surveillance, Epidemiology, and End Results (SEER) database from 1998 to 2016, we established the Cox proportional-hazards and competing-risks model to retrospectively analyze the impact of related factors on lymph nodes statistically.

Results
A total of 2,435 patients were included in the analysis, of which 198 died of MTC. The results of the multifactor competing-risk model showed that the number of total lymph nodes (19–89), positive lymph nodes (1–10,11–75) and positive lymph node ratio (25%-53%,>54%), age (46–60,>61), chemotherapy, mode of radiotherapy (others), tumor size(2-4cm,>4cm), number of lesions greater than 1 were poor prognostic factors for MTC. For the number of total lymph nodes, unlike the multivariate Cox proportional-hazards model results, we found that it became an independent risk factor after excluding competitive risk factors. Competitive risk factors have little effect on the number of positive lymph nodes. For the proportion of positive lymph nodes, we found that after excluding competitive risk factors, the Cox proportional-hazards model overestimates its impact on prognosis. The competitive risk model is often more accurate in analyzing the effects of prognostic factors.

Conclusions
After excluding the competitive risk, the number of lymph nodes, the number of positive and the positive proportion are the poor prognostic factors of medullary thyroid cancer, which can help clinicians more accurately evaluate the prognosis of patients with medullary thyroid cancer and provide a reference for treatment decision-making.
Endoscopic Features of Post–COVID-19 Cholangiopathy and Its Management Using ERCP
Authors: Leonhardt Silke , Grajecki Donata , Geisel Dominik , Fehrenbach Uli , Adler Andreas , Leonhardt Julia , Horst David , Kurth Florian , Thibeault Charlotte , Janssen Hans-Joachim , Kaul Thomas , Faiss Siegbert , Tacke Frank , Jürgensen Christian 
Published: October 2023

INTRODUCTION:
Despite growing awareness of post–coronavirus disease 2019 (COVID-19) cholangiopathy as one of the most serious long-term gastrointestinal consequences of COVID-19, the endoscopic features of this disease are still poorly characterized. This study aimed to more precisely define its endoscopic features and to outline the role of endoscopic retrograde cholangiopancreatography (ERCP) in the management of this entity.

METHODS:
In this observational study, 46 patients with confirmed post–COVID-19 cholangiopathy were included.

RESULTS:
Based on the endoscopic features observed in 141 ERCP procedures, post–COVID-19 cholangiopathy can be classified as a variant of secondary sclerosing cholangitis in critically ill patients. It appeared early in the course of intensive care treatment of patients with COVID-19 (cholestasis onset 4.5 days after intubation, median). This form of cholangiopathy was more destructive than stricturing in nature and caused irreversible damage to the bile ducts. A centripetal pattern of intrahepatic bile duct destruction, the phenomenon of vanishing bile ducts, the absence of extrahepatic involvement, and the presence of intraductal biliary casts (85% of patients) were typical cholangiographic features of post–COVID-19 cholangiopathy. This cholangiopathy was often complicated by small peribiliary liver abscesses with isolation of Enterococcus faecium and Candida spp. in bile culture. The prognosis was dismal, with a 1-year liver transplantation–free survival rate of 44%. In particular, patients with peribiliary liver abscesses or destruction of the central bile ducts tended to have a poor prognosis (n.s.). As shown by multivariate analysis, bilirubin levels (on intensive care unit day 25–36) negatively correlated with liver transplantation–free survival (hazard ratio 1.08, P < 0.001). Interventional endoscopy with cast removal had a positive effect on cholestasis parameters (gamma-glutamyl transpeptidase, alkaline phosphatase, and bilirubin); approximately 60% of all individual values decreased.

DISCUSSION:
Gastrointestinal endoscopy makes an important contribution to the management of post–COVID-19 cholangiopathy. ERCP is not only of great diagnostic and prognostic value but also has therapeutic value and therefore remains indispensable.