bluuebunny/crossref_metadata_2025_split huggingface dataset:
STOCK PRICE PREDICTION USING ARTIFICIAL NEURAL NETWORKS WITH THE ADALINE METHOD
Authors: Sona Rama , Hastono Tri Hastono , Anjasmara Pipim Diaz 
Published: October 2023

Prediction of stock prices has an important role in making investment decisions in financial markets. In this study, researchers propose the use of artificial neural networks with the Adaline method to predict stock prices. The Adaline method is a learning algorithm that iteratively adapts network weights to minimize prediction errors. In the early stages, researchers collect relevant stock price historical data and process it into a training dataset. Next, build an artificial neural network with one input layer, one output layer, and use a linear activation function. The network weights are initialized randomly, and the training process begins. In network training, the researcher applies the Adaline algorithm with the descending gradient method to optimize the objective function. The researcher updates the network weights based on the difference between the actual stock price and the stock price predicted by the network. This process is repeated iteratively until it converges or reaches the specified stopping criteria. After the training is complete, the researcher evaluates the network performance using validation data that was not used in the training. Researchers used evaluation metrics, such as the mean absolute error (MAE) and root mean square error (RMSE), to measure the accuracy of network predictions. In addition, researchers also compared the performance of the Adaline network with other prediction methods, such as linear regression.
The experimental results show that the artificial neural network with the Adaline method is able to provide accurate stock price predictions. Researchers observed a significant reduction in prediction error compared to the linear regression method. In addition, the Adaline network also shows good adaptability to changes in market trends. This research makes an important contribution to the development of stock price prediction methods using artificial neural networks. The results can be used as a guide for investors and stock traders to make more informed and effective investment decisions.
Keywords : stock price prediction, artificial neural network, Adaline method, learning algorithm, performance evaluation.
Un nuovo libro sulla «lex Voconia»
Authors: Battistini Simone 
Published: October 2023

Abstract - The theme of the lex Voconia is illustrated by the author in an innovative way with respect to the previous bibliography on the subject, focusing on the rationale of the lex of wanting to affect the juridical-social position of women. It is illustrated how the provision was often evaded – also through recourse to historical sources – and how, despite the validity of the law, there were Roman marriages in possession of large assets. The problem of female succession thus presents itself as a starting point for reflection on the juridical status of women.
Da ‘opus’ a ‘opera’: considerazioni tra lingua e diritto
Authors: Ceglia Luca 
Published: October 2023

Abstract - The linguistic derivation of ‘opera’ from ‘opus’ allows us to advance useful hypotheses on the recent nature of the locatio operarum. From the primitive unity of the locatio-conductio the locatio operarum would in fact have detached itself from the locatio rei in order to move the object of the assignment from the person of the worker to his activity and thus allow the work of the free man who subjected himself imperio alterius et potestati (Cic. Off. 22) for economic reasons. An attraction towards the obligation to do from the original obligation to give would have been exercised precisely by the locatio operis, which left the worker with greater managerial autonomy, limiting the control of the counterpart to the fairness of the corpus perfectum to be returned, without dividing the actions into individual operae to be carried out under the guidelines of others.
Discorso minimo sopra la «Consultatio veteris cuiusdam iurisconsulti»
Authors: Giomaro Anna Maria 
Published: October 2023

Abstract - The article aims to illustrate the topic of Consultatio veteris cuiusdam iurisconsulti based on the latest studies, briefly considering its various aspects (bibliography, discovery of the manuscript, its edition, formal and content aspects, nature of the work). The approach is particularly problematic, aimed at pointing out the doubts and perplexities that persist and require new solutions or hypotheses. In particular, the emphasis is placed on the possibility of a more concrete use for the particular study of the sources that appear in it (individual norms of the Gregorian, the Hermogenian, the Theodosian, the Pauli Sententiae) and their development in the Late Antiquity centuries, thanks to the specific comparison with the tradition in common use.
Il nutrimento dell'infante tra costume e diritto
Authors: Perani Renato 
Published: October 2023

Abstract - In ancient Rome, the phenomenon of infants fed by hired nurses could be dated back as early as the late republic. The practice became even more widespread during the imperial age, owing to the updating social customs and the medical culture of that time. Although it is widely believed in the literature that the age of the Antonines there was an attempt to curb this tendency, by reverting back to encouraging mothers to assume the role of feeding the infants, there is no specific legislative intervention to attest. However, my research points out that the testimony of Gellius, who reports on Favorinus, a strenuous defender of traditional maternal care for infants, and some other sources from the 2nd century seem to give actual confirmation of the great topicality of this subject at that historical moment.
L’ «aequitas» a Sofistopoli. Note sull’ «aequitas» nell’antologia di Seneca padre
Authors: Rizzelli Giunio 
Published: October 2023

Abstract - The paper deals with aequitas and its relationship to ius from the perspective of the declaimers of Seneca the father’s anthology of controversiae, a scholastic practice in many ways connected to the world of jurists, which also teaches to apply rhetorical status theory, in turn of great importance for the development of jurisprudence. In them, aequitas, which appears in the divisio between quaestiones iuris and quaestiones aequitatis or tractationes, adapts the ius, general and abstract, produced by the lex to the individual concrete case without opposing it.
Considerazioni minime sulla terminologia tardoantica negli interventi sui testi classici
Authors: Zuccotti Ferdinando 
Published: October 2023

Abstract - Starting from the 1950s, the reaction to the interpolation critique, on the one hand, allowed the abandonment of an extremism that had led to excesses and apriorisms, and on the other, led to an anti-interpolationist extremism and to a consequent superficiality in the study of the sources, approached in a sectorial and uncritical manner, rejecting any possibility of their alteration. Illustrative of such illogical genuinism are the attempts to save two texts, namely D. 8.5.10. pr.-1 and D. 39.3.1.23, which, despite appearing to raise insurmountable problems both as regards the terminology and therefore the conceptualisations used by them, and especially the legal regulation of iura in re aliena implied by them, are considered classical. Urgent then is the need to revise this tendency, aspiring to a «critical neo-interpolationism», centred on the historical study of the text and on the identification of its possible various drafts - focusing on the specific reasons that led the late antique jurist or the Justinian commissioner to that specific type of intervention on the classical text - with the consequent return of the sources to their intrinsic diachrony.
Overvåking av graving i gårdshaugen i Kilbotn, Harstad k.
Authors: Henriksen Jørn Erik 
Published: October 2023

Overvåking av grøfting og annet gravearbeid i forbindelse med nytt vann og avløpsanlegg til Aspelivegen 11 og 13 ble gjennomført i perioden 20-22 juni 2022. Arbeidet berørte gårdshaugen Id. 28739-1, i kulturminnets sørlige del.
To områder med bevarte gårdshaugmasser ble dokumentert, profil 1 i det vestre området som ble berørt av tiltaket og profil 2 noe lenger øst i grøfteområdet. Profil 1 viste to meter kulturlag, hvorav 50 cm i bunn tolkes som meget intakt gårdshaug. Prøve fra en trekull- og askekonsentrasjon sentralt i disse kulturlagene ble datert til høymellomalder.
En prøve fra en lignende kontekst i profil 2 ble datert til seinmellomalder/tidlig nytid. Kulturlagene i dette var 30-50 cm tykke, og har trolig i sin helhet blitt avsatt på senere tid enn mellomalderlagene dokumentert i profil 1.
Konklusjonen er at kulturminnets planavgrensning i Askeladden og antydede dybde (opptil 3-4 m), trolig er korrekt. Datering til mellomalder er også sannsynliggjort med denne overvåkingen, men mulighetene for eldre dateringer holdes åpne siden det ikke foreligger datering av bunnlag i profil 1.
Association between serum ferritin and uric acid levels and nonalcoholic fatty liver disease in the Chinese population
Authors: Zhou Fangli , He Xiaoli , Liu Dan , Ye Yan , Tian Haoming , Tian Li 
Published: October 2023

Background
The prevalence of nonalcoholic fatty liver disease (NAFLD) is increasing worldwide. Accumulating evidence suggests that serum ferritin and uric acid (UA) are strongly associated with the risk of NAFLD, but no consensus has been reached.

Objective
We sought to demonstrate the association between serum ferritin, UA levels, and NAFLD risk in a large cohort study.

Methods
We separated 2,049 patients into non-NAFLD and NAFLD groups. The NAFLD group had four subgroups based on serum ferritin and four subgroups based on UA quartile levels. We used binary logistic regression to evaluate the correlation between serum ferritin, UA, and NAFLD. Additionally, an area under the curve (AUC) of receiver operating characteristic analysis (ROC) was used to predict the diagnostic value of combined serum ferritin and UA for NAFLD.

Results
Serum ferritin and UA levels were higher in the NAFLD group compared with the non-NAFLD group. Serum lipid and liver transaminase concentrations were elevated with the increase of serum ferritin and UA. The logistic regression results showed an independent correlation between serum ferritin, UA, and NAFLD. In the NAFLD group, the AUC value of serum ferritin and UA was 0.771.

Conclusions
Increased serum ferritin and UA levels are independent risk factors for NAFLD. Increased serum UA is a stronger risk factor for NAFLD than elevated serum ferritin. Serum ferritin and UA can be important predictors of NAFLD risk.
High-risk histological subtype-related FAM83A hijacked FOXM1 transcriptional regulation to promote malignant progression in lung adenocarcinoma
Authors: Fei Wei , Yan Yan , Liu Guangjun , Peng Bo , Liu Yuanyuan , Chen Qiang 
Published: October 2023

Background
According to the histopathology, lung adenocarcinoma (LUAD) could be divided into five distinct pathological subtypes, categorized as high-risk (micropapillary and solid) group, intermediate-risk (acinar and papillary) group, and low-risk (lepidic) group. Despite this classification, there is limited knowledge regarding the role of transcription factors (TFs) in the molecular regulation of LUAD histology patterns.

Methods
Publish data was mined to explore the candidate TFs associated with high-risk histopathology in LUAD, which was validated in tissue samples. Colony formation, CCK8, EdU, transwell, and matrigel assays were performed to determine the biological function of FAM83A in vitro. Subcutaneous tumor-bearing in BALB/c nude mice and xenograft perivitelline injection in zebrafish were utilized to unreal the function of FAM83A in vivo. We also performed chromatin immunoprecipitation (ChIP), dual-luciferase reporter, and rescue assays to uncover the underline mechanism of FAM83A. Immunohistochemistry (IHC) was performed to confirm the oncogenic role of FAM83A in clinical LUAD tissues.

Results
Screening the transcriptional expression data from TCGA-LUAD, we focus on the differentially expressed TFs across the divergent pathological subtypes, and identified that the expression of FAM83A is higher in patients with high-risk groups compared with those with intermediate or low-risk groups. The FAM83A expression is positively correlated with worse overall survival, progression-free survival, and advanced stages. Gain- and loss-of-function assays revealed that FAM83A promoted cell proliferation, invasion, and migration of tumor cell lines both in vivo and in vitro. Pathway enrichment analysis shows that FAM83A expression is significantly enriched in cell cycle-related pathways. The ChIP and luciferase reporter assays revealed that FAM83A hijacks the promoter of FOXM1 to progress the malignant LUAD, and the rescue assay uncovered that the function of FAM83A is partly dependent on FOXM1 regulation. Additionally, patients with high FAM83A expression positively correlated with higher IHC scores of Ki-67 and FOXM1, and patients with active FAM83A/FOXM1 axis had poor prognoses in LUAD.

Conclusions
Taken together, our study revealed that the high-risk histological subtype-related FAM83A hijacks FOXM1 transcriptional regulation to promote malignant progression in lung adenocarcinoma, which implies targeting FAM83A/FOXM1 is the therapeutic vulnerability.
The Influence of Knowledge Management on Increasing Innovation and Competitive Advantage in the Private University Sector in Kuwait
Authors: Shebaib Shebaib Fahad 
Published: October 2023

The main aim of current study is to examine the influence of knowledge management KM (Knowledge Creation, Knowledge acquisition, Knowledge sharing, Knowledge storage, Knowledge dissemination, Knowledge utilization, Knowledge retention) in increasing innovation capability IC and competitive advantage CA within private universities sector in the state of Kuwait. The study launched its aim through the aid of resource-based view theory which states that non-tangible assists of an organization help in supporting its journey to competitiveness and innovation. Through depending on quantitative methodology, a questionnaire was distributed on a sample of (303) respondents from private universities sector in the state of Kuwait. SPSS was used to deal with primary data depending on multiple regression and Pearson correlation. Results indicated the acceptance of the fact that KM has the ability to increase innovative abilities and competitive advantage within private universities sector in the state of Kuwait. Influence of KM on innovation capability appeared to be higher with a variance of 94.9% compared to competitive advantage which was also influenced by KM with a variance of 92.3%. Results also indicated that there was a correlation between variables of KM and both variables of competitive advantage and innovation capability. The highest relationship was between Knowledge sharing and Innovation Capability; whereas the highest relationship was between Knowledge storage and Competitive Advantage. Study recommended organizations should focus more on training and development in the field of knowledge storing and retaining so employees can have more awareness of how to deal with knowledge through their daily tasks.
Effect of Sowing Methods and Nitrogen Levels on Growth, Yield and Economics of Oats (Avena sativa L.) under Mid-Hills of Himachal Pradesh, India
Authors: Sharma Parv , Choudhary Kartikeya 
Published: October 2023

In Himachal Pradesh, farmers typically possess small land holdings where machinery isn't practical for various sowing techniques, limiting them to broadcasting. Regarding nitrogen, it facilitates more vegetative growth by enhancing the photosynthetic rate. The higher the nitrogen content, the greater the vegetative growth potential. Therefore, present investigation titled “Effect of Sowing Methods and Nitrogen Levels on Growth, Yield and Economics of Oats (Avena sativa L.) under Mid-hills of Himachal Pradesh, India” was conducted during rabi season of 2022-23 at Chamelti Agriculture Farm, MS Swaminathan School of Agriculture, Shoolini University of Biotechnology and Management Sciences, Solan, Himachal Pradesh. The field experiment was laid out in Split Plot Design comprising twelve treatments with three replications. The experiment consists of three sowing methods in main plot i.e., (S1) Broadcasting, (S2) Line sowing and (S3) Crisscross and four levels of nitrogen N0 (0 kg ha-1), N1 (75 kg ha-1), N2 (100 kg ha-1) and N3 (125 kg ha-1) as sub plot. OL 12 variety of oats was used for sowing. Sowing methods and nitrogen levels were done as per treatment. Other crop management practices were followed as per the recommendation of the area. Results indicated that among the sowing methods, (S3) crisscross, recorded significantly higher growth and yield, over line sowing and broadcasting which was on par with (S2) line sowing over the rest of the treatments except for grain, straw and biological yield. In case of nitrogen levels, (N3) application of 125 kg N ha-1 recorded significantly higher growth and yield of oats, over rest of the nitrogen levels and was on par with 100 kg N ha-1. Economically, (S3) crisscross sowing with application of (N3) 125 kg N ha-1 resulted in higher gross returns, net returns and B: C ratio under Mid Hills of Himachal Pradesh.
The Effect of Tannic Acid as Antimicrobial Agent on Pseudomonas aeruginosa Using In-vitro Diffusion Method
Authors: Sardjiman  , Rahardjoputro Rolando , Santoso Joko 
Published: October 2023

Background: Bacterial infection is a health problem that has long been attention in the world of health. Various antimicrobials have been discovered and developed by researchers to solve pathogenic bacterial infections. Pseudomonas aeruginosa is a pathogenic bacteria that is often of concern to researchers because it has the potential to become resistant to a number of antibiotics. Tannic acid is known to have potential antibacterial activity against pathogenic bacteria. The antibacterial activity of tannic acid is interesting to study considering its great potential as an antimicrobial agent for pathogenic bacterial infections.
Aims: To find out the antibacterial potential of tannic acid compounds against Pseudomonas aeruginosa In-vitro using the disc diffusion method.
Methodology: This research is quantitative research with experimental methods. This research was carried out at the Pharmacy Laboratory of Kusuma Husada Surakarta University, Indonesia between April and May 2023. The sample for this study was a certified bacterial culture of Pseudomonas aeruginosa ATCC 27853 originating from a stock culture from the laboratory. We use certified tannic acid from Merck Millipore. The tannic acid in powder form was dissolved in a 1% DMSO solution. The sample solution containing tannic acid in 1% DMSO was dropped on a Kirby-Bauer disk and placed on an agar plate inoculated with bacteria. One petri dish contains five discs with different samples placed at adequate distances. There were 0.5% tannic acid solution, 1% tannic acid solution, and 2% tannic acid solution, negative control 1% DMSO solution and positive control ciprofloxacin 5 µg/ml. Replication was carried out five times.
Results: Tannic acid with a concentration of 0.5% has an average inhibitory zone of 102 mm. A 1% concentration of tannic acid has an average inhibitory zone of 121 mm. A 2% concentration of tannic acid has an average inhibitory zone of 150 mm. The positive control used, namely the antibiotic ciprofloxacin, obtained an average inhibitory zone of 350 mm. The negative control used, namely 1% DMSO solution, had no inhibitory zone at all. Statistical tests using the Kruskal-Wallis test showed that there was a significant difference with a value of p = 0.000.
Conclusion: The tannic acid compound is an active compound that has antimicrobial activity against Pseudomonas aeruginosa ATCC 27853 and its application in health can be considered.
Ceftriaxone and the Risk of Ventricular Arrhythmia, Cardiac Arrest, and Death Among Patients Receiving Lansoprazole
Authors: Bai Anthony D. , Wilkinson Amelia , Almufleh Aws , Rai Mandip , Razak Fahad , Verma Amol A. , Srivastava Siddhartha 
Published: October 2023

ImportanceThe combination of ceftriaxone and lansoprazole has been shown to prolong the corrected QT interval on electrocardiogram. However, it is unknown whether this translates to clinically important patient outcomes.ObjectiveTo compare lansoprazole with another proton pump inhibitor (PPI) during ceftriaxone treatment in terms of risk for ventricular arrhythmia, cardiac arrest, and in-hospital mortality.Design, Setting, and ParticipantsA retrospective cohort study including adult medical inpatients receiving ceftriaxone with lansoprazole or another PPI in 13 hospitals in Ontario, Canada, was conducted from January 1, 2015, to December 31, 2021.ExposureLansoprazole during ceftriaxone treatment vs other PPIs during ceftriaxone treatment.Main Outcomes and MeasuresThe primary outcome was a composite of ventricular arrhythmia or cardiac arrest that occurred after hospital admission. The secondary outcome was all-cause in-hospital mortality. Propensity-score weighting was used to adjust for covariates including hospital site, demographic characteristics, comorbidities, risk factors for ventricular arrhythmia, illness severity, admitting diagnoses, and concomitant medications.ResultsOf the 31 152 patients hospitalized on internal medicine wards who were treated with ceftriaxone while receiving a PPI, 16 135 patients (51.8%) were male, and the mean (SD) age was 71.7 (16.0) years. The study included 3747 patients in the lansoprazole group and 27 405 patients in the other PPI group. Ventricular arrhythmia or cardiac arrest occurred in 126 patients (3.4%) within the lansoprazole group and 319 patients (1.2%) within the other PPI group. In-hospital mortality occurred in 746 patients (19.9%) within the lansoprazole group and 2762 patients (10.1%) in the other PPI group. After weighting using propensity scores, the adjusted risk difference for the lansoprazole group minus other PPI group was 1.7% (95% CI, 1.1%-2.3%) for ventricular arrhythmia or cardiac arrest and 7.4% (95% CI, 6.1%-8.8%) for in-hospital mortality.Conclusions and RelevanceThe findings of this cohort study suggest that combination therapy with lansoprazole and ceftriaxone should be avoided. More studies are needed to determine whether these findings could be replicated in other populations and settings.