bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lewis Caerleon and the equation of time: tabular astronomical practices in late fifteenth-century England
Authors: Miolo Laure , Zieme Stefan 
Published: January 2024

AbstractThe manuscripts and writings of the fifteenth-century astronomer and physician Lewis Caerleon (d.c.1495) have been largely overlooked. To fill this gap, this article focuses on his writings and working methods through a case study of his canons and table for the equation of time. In the first part, an account of his life and writings is given on the basis of new evidence. The context in which his work on the equation of time was produced is explored in detail by reviewing the three key periods of his scientific production. His heavy reliance on Simon Bredon’sCommentum super Almagestiis also analyzed. The article also provides editions of Lewis Caerleon’s canons for calculating his table for the equation of time and a critical edition of Simon Bredon’sCommentum super Almagesti,III, 22–24. In the second part of this article, we analyze the table for the equation of time derived by Lewis around 1485. In addition to the final table, there is a unique table with intermediate results that records every step of his derivation. By following and discussing the details of this derivation, we shed a new light on tabular practices in mathematical astronomy. Following Lewis in his historical mathematical procedure, we argue, offers a novel historiographical approach that allows us to identify different sources and practices used by historical actors. Therefore, beyond the exchange of parameters residing in modern mathematical analysis, this novel approach offers a promising refinement for the analysis of the transmission of knowledge across space, time, and culture.
Survival of dental implants and occurrence of mucosal overgrowth in patients with head and neck cancer treated with/without radiotherapy and mucosal graft—two-year follow-up
Authors: Mattila Viivi , Wilkman Tommy , Avellán Nina-Li , Mesimäki Karri , Furuholm Jussi , Ruokonen Hellevi , Nylund Karita 
Published: January 2024

Abstract
Objectives
The primary aim of the present study was to compare head and neck cancer treatment modality surgery and surgery with radiotherapy or chemoradiotherapy alone for dental implant (DI) survival. The second aim was to evaluate the prevalence of mucosal overgrowth around DI after treatment with or without mucosal grafts.

Materials and methods
An observational retrospective study consisted of 59 patients with malignant head and neck tumors that received DI between 2015 and 2019. Treatment modalities together with information on oral rehabilitation with DI, prevalence of mucosal overgrowth, and precursor lesions were gathered from the hospital records. Radiation doses were determined using a sum of three-dimensional dose distributions.

Results
Overall DI survival rate was 88%, in irritated jaw 89%, and in nonirradiated jaw 88% in this observational period (p = 0.415, mean follow-up was 2 years 10 months, range 9–82 months). Mucosal overgrowth was found in 42 of 196 implants (21%), of which 36 cases (86%) were associated in grafted areas (p < 0.001). Oral lichen planus/lichenoid reaction was diagnosed in 14 of all 59 (24%) oral cancer patients.

Conclusion
Implant survival was not significantly influenced by radiation therapy in this observational period. In grafted bone, implant survival was significantly inferior than in native bone. Mucosal overgrowth around implants was more common in mucosal grafted areas versus nongrafted.

Clinical relevance
This study demonstrates the impact of grafted bone to dental implant survival rate and mucosal overgrowth.
A molecular toolbox for fast and convenient diagnosis of emerging and reemerging bacterial pathogens causing fever of intermediate duration
Authors: Vega-García Elva , Palacios Génesis , Pérez José A. , Vélez-Tobarias Mónica , Torres-Vega Ana María , Ascaso-Terrén Carlos , Carmelo Emma 
Published: January 2024

Abstract
Purpose
Fever of intermediate duration (FID) is defined as a fever in the community without a specific origin or focus, with a duration between 7 and 28 days. FID is often caused by pathogens associated with animal contact or their arthropods parasites, such as ticks, fleas, or lice. The purpose of this work is to design a collection of molecular tools to promptly and accurately detect common bacterial pathogens causing FID, including bacteria belonging to genera Rickettsia, Bartonella, Anaplasma, and Ehrlichia, as well as Coxiella burnetii.

Methods
Reference DNA sequences from a collection of Rickettsia, Bartonella, Anaplasma, and Ehrlichia species were used to design genus-specific primers and FRET probes targeted to conserved genomic regions. For C. burnetii, primers previously described were used, in combination with a newly designed specific probe. Real-time PCR assays were optimized using reference bacterial genomic DNA in a background of human genomic DNA.

Results
The four real-time PCR assays can detect as few as ten copies of target DNA from those five genera of FDI-causing bacteria in a background of 300 ng of human genomic DNA, mimicking the low microbial load generally found in patient’s blood.

Conclusion
These assays constitute a fast and convenient “toolbox” that can be easily implemented in diagnostic laboratories to provide timely and accurate detection of bacterial pathogens that are typical etiological causes of febrile syndromes such as FID in humans.
The contemporary nexus of medicines security and bioprospecting: a future perspective for prioritizing the patient
Authors: Cordell Geoffrey A. 
Published: January 2024

AbstractReacting to the challenges presented by the evolving nexus of environmental change, defossilization, and diversified natural product bioprospecting is vitally important for advancing global healthcare and placing patient benefit as the most important consideration. This overview emphasizes the importance of natural and synthetic medicines security and proposes areas for global research action to enhance the quality, safety, and effectiveness of sustainable natural medicines. Following a discussion of some contemporary factors influencing natural products, a rethinking of the paradigms in natural products research is presented in the interwoven contexts of the Fourth and Fifth Industrial Revolutions and based on the optimization of the valuable assets of Earth. Following COP28, bioprospecting is necessary to seek new classes of bioactive metabolites and enzymes for chemoenzymatic synthesis. Focus is placed on those performance and practice modifications which, in a sustainable manner, establish the patient, and the maintenance of their prophylactic and treatment needs, as the priority. Forty initiatives for natural products in healthcare are offered for the patient and the practitioner promoting global action to address issues of sustainability, environmental change, defossilization, quality control, product consistency, and neglected diseases to assure that quality natural medicinal agents will be accessible for future generations.Graphical Abstract
Microstructural and mechanical properties of electron beam welded super duplex stainless steel
Authors: Tóth Tamás , Hesse Ann-Christin , Kárpáti Viktor , Mertinger Valéria , Dilger Klaus 
Published: January 2024

AbstractThe electron beam welding of super duplex stainless steels is associated with challenges due to the concentrated heat input and the nitrogen loss that result in a predominantly ferritic structure after the solidification. This study presents an approach to overcome this issue by feeding nickel-based filler wire into the melt pool in welding of 2507 super duplex stainless steel. Results showed that the high-frequency beam oscillation combined with a multi-beam technique led a good mixing between the base metal and the filler wire, even at a large depth-to-width ratio. Additionally, the weld geometry was characterized by near-parallel fusion lines and a narrow heat-affected zone. The nickel addition resulted in a balanced microstructure in the weld metal with ferrite fractions of 35–55 %, despite a significant nitrogen loss, consequently leading to impact energy values of 215 ± 15 J and hardness values of 285 ± 15 HV. The findings of this investigation allow fabricators to effectively design electron beam welding processes for producing thick-walled super duplex stainless steel components.
University ‘Pay-for-grades’: the bait and switch search engine optimization strategies of contract cheating websites in the United States
Authors: Daly Timothy M. , Ryan James C. 
Published: January 2024

AbstractThis paper presents the first systematic investigation into the search engine optimization practices of major contract cheating websites in the United States. From a business perspective, visibility in organic search engine results is considered one of the top client recruitment tools. The current understanding of student recruitment strategies by these companies remains largely unexplored in both academic literature and popular press. Replicating the business research practices used in the search engine optimization industry, comprehensive search engine ranking and traffic data was obtained for the 38 largest contract cheating websites in the US. The overall objective was to illuminate the strategies that these companies take to get their services at the top of the search results of as many students as possible – not just the relatively small proportion of students actively cheating. The results show that these companies dominate the search results for not just students searching to cheat, but also for naïve search efforts, when students are simply doing genuine research or classwork. These nefarious companies use highly sophisticated search engine manipulation strategies to bait naïve student searchers onto their sites, thus enabling the potential to switch them to cheaters. Higher education institutions, armed with the specific details provided in this study, can use the strategies outlined in the discussion to directly and negatively impact on the success of these contract cheating services.
Informing future directions for climate anxiety interventions: a mixed-method study of professional perspectives
Authors: Pitt Clare , Norris Kimberley , Pecl Gretta 
Published: January 2024

AbstractDespite reports of increasing levels of climate change related distress, there remains limited evidence regarding effective interventions for individuals and communities. The current study aims to contribute to this discussion by presenting opinions from study participants who self-identified as having a professional interest in climate anxiety. An international interdisciplinary survey was conducted, with qualitative and quantitative responses from 230 participants, from a range of professional backgrounds, including a range of mental health practitioners, along with climate activists, artists, educators, academics and scientists and others interested in the climate anxiety space. A wide range of potential components of climate anxiety interventions were suggested by participants, including supporting people to connect with others and nature, emotional validation in a group setting, and moving toward climate action. Reflexive thematic analysis of qualitative data resulted in five themes: ‘Climate anxiety is a healthy response to the current situation’, ‘Climate anxiety will continue to increase until there is climate action’, ‘Climate anxiety interventions should be individualised’, ‘Climate anxiety interventions need to include the community and societal level’ and ‘Climate-aware practitioners are required’. These themes provide a significant contribution to the discourse on climate anxiety interventions. They emphasize the need for an understanding of climate anxiety as a legitimate response to the current situation and the imperative of community and society levels being included in intervention strategies. Results from this study provide insights from diverse perspectives to provide valuable guidance for future research and practice in the development of effective interventions for climate anxiety.
Improved Soft-Skill Competencies of ABA Professionals Following Training and Coaching: A Feasibility Study
Authors: Friedman Zahava L. , El Roy Daphna , Kerwin Emily , Tirri Gina , Broff Angela 
Published: January 2024

AbstractThe field of applied behavior analysis currently faces critique regarding the need for increased compassion and interprofessional collaboration training toward culturally and emotionally responsive practice. Mindful self-compassion is evidenced to improve self-compassion and compassion. The purpose of the current study was to improve soft-skill competencies in collaboration and compassion of behavior analytic professionals. In this feasibility study, two cohorts of American behavior analytic professionals (N = 24) received a 4-month training-and-coaching sequence, with a pre-program focus group serving as the program’s needs assessment. The Interprofessional Collaborative Competency Attainment Survey and Self-Compassion Scale, Short Form were administered pre- and post-intervention to ascertain program effectiveness, alongside open-ended survey questions. Training included experiential learning opportunities in small groups, with participants practicing self-compassion and collaboration skills. Coaching included additional individual practice opportunities. Pre- and post-whole test scores were significantly different on both instruments, with p set at .05, demonstrating preliminary effectiveness. Significance on paired-sample t-test for the Interprofessional Collaborative Competency Attainment Survey whole score fell at <.001, while for the Self-Compassion Scale, Short Form, it fell at .004. While prior studies have demonstrated the need for collaboration and compassion training within the ABA workforce, the current study reports on an implementation procedure to improve upon these skill sets, addressing a noted gap. Furthermore, the current study operationalizes collaboration alongside self-compassion, demonstrating the importance of centering collaborative practice within soft-skill awareness and competency. Future research can incorporate direct measures of these skill sets.
Whole-genome sequencing of Fusarium spp. causing sugarcane root rot on both chewing cane and sugar-making cane
Authors: Li Xinyang , Ma Yuming , Zhang Na , Li Yiming , Liang Zhibin , Luo Yibao , Lin Longxin , Zhang Dongliang , He Yongqiang , Wang Ziting , Zhang Zhiquan , Deng Yizhen 
Published: January 2024

AbstractPreviously we isolated three Fusarium strains (a F. sacchari strain namely GXUF-1, and another two F. commune strains namely GXUF-2 and GXUF-3), and we verified that GXUF-3 was able to cause sugarcane root rot to the chewing cane cultivar Badila. Considering that Fusarium spp. are a group of widely distributed fungal pathogens, we tested whether these three Fusarium isolates were able to cause root rot to Badila as well as sugar-making cane cultivar (Guitang42), using a suitable inoculation method established based on infection assays using Badila. We found that the three Fusarium strains were able to cause root rot symptoms to both Badila and Guitang42, to different extents. To better investigate the potential pathogenicity mechanisms, we performed Illumina high-throughput sequencing and analyzed the whole genomic sequence data of these three Fusarium strains. The results reveal that the assembly sizes of the three Fusarium strains were in a range of 44.7–48.2 Mb, with G + C contents of 48.0–48.5%, and 14,154–15,175 coding genes. The coding genes were annotated by multiple public databases, and potential pathogenic genes were predicted using proprietary databases (such as PHI, DFVF, CAZy, etc.). Furthermore, based on evolutionary analysis of the coding sequence, we found that contraction and expansion of gene families occurred in the three Fusarium strains. Overall, our results suggest a potential risk that the root rot disease may occur to the sugar-making canes although it was initially spotted from fruit cane, and provide clues to understand the pathogenic mechanisms of Fusarium spp. causing sugarcane root rot.
Development of a novel primate welfare assessment tool for research macaques
Authors: Paterson Emilie A , O’Malley Carly I , Abney Dawn M , Archibald William J , Turner Patricia V 
Published: January 2024

Abstract
Primates are important species for biomedical research and ensuring their good welfare is critical for research translatability and ethical responsibility. Systematic animal welfare assessments can support continuous programme improvements and build institutional awareness of areas requiring more attention. A multi-facility, collaborative project aimed to develop and implement a novel primate welfare assessment tool (PWAT) for use with research macaques. PWAT development involved: establishing an internal focus group of primate subject matter experts, identifying animal welfare categories and descriptors based on literature review, developing a preliminary tool, beta-testing the tool to ensure practicality and final consensus on descriptors, finalising the tool in a database with semi-automated data analysis, and delivering the tool to 13 sites across four countries. The tool uses input- and outcome-based measures from six categories: physical, behavioural, training, environmental, procedural, and culture of care. The final tool has 133 descriptors weighted based upon welfare impact, and is split into three forms for ease of use (room level, site level, and personnel interviews). The PWAT was trialled across facilities in March and September 2022 for benchmarking current macaque behavioural management programmes. The tool successfully distinguished strengths and challenges at the facility level and across sites. Following this benchmarking, the tool is being applied semi-annually to assess and monitor progress in behavioural management programmes. The development process of the PWAT demonstrates that evidence-based assessment tools can be developed through collaboration and consensus building, which are important for uptake and applicability, and ultimately for promoting global improvements in research macaque welfare.
Narrative review of telemedicine applications in decentralized research
Authors: Cummins Mollie R. , Soni Hiral , Ivanova Julia , Ong Triton , Barrera Janelle , Wilczewski Hattie , Welch Brandon , Bunnell Brian E. 
Published: January 2024

Abstract
Telemedicine enables critical human communication and interaction between researchers and participants in decentralized research studies. There is a need to better understand the overall scope of telemedicine applications in clinical research as the basis for further research. This narrative, nonsystematic review of the literature sought to review and discuss applications of telemedicine, in the form of synchronous videoconferencing, in clinical research. We searched PubMed to identify relevant literature published between January 1, 2013, and June 30, 2023. Two independent screeners assessed titles and abstracts for inclusion, followed by single-reviewer full-text screening, and we organized the literature into core themes through consensus discussion. We screened 1044 publications for inclusion. Forty-eight publications met our inclusion and exclusion criteria. We identified six core themes to serve as the structure for the narrative review: infrastructure and training, recruitment, informed consent, assessment, monitoring, and engagement. Telemedicine applications span all stages of clinical research from initial planning and recruitment to informed consent and data collection. While the evidence base for using telemedicine in clinical research is not well-developed, existing evidence suggests that telemedicine is a potentially powerful tool in clinical research.
Integrating data, knowledge, and expertise for policy advice: understanding the practices of Dutch organized crime control professionals
Authors: van Rij Wybren , Dekker Rianne , Meijer Albert 
Published: January 2024

Abstract
Current research on data in policy has primarily focused on street-level bureaucrats, neglecting the changes in the work of policy advisors. This research fills this gap by presenting an explorative theoretical understanding of the integration of data, local knowledge and professional expertise in the work of policy advisors. The theoretical perspective we develop builds upon Vickers’s (1995, The Art of Judgment: A Study of Policy Making, Centenary Edition, SAGE) judgments in policymaking. Empirically, we present a case study of a Dutch law enforcement network for preventing and reducing organized crime. Based on interviews, observations, and documents collected in a 13-month ethnographic fieldwork period, we study how policy advisors within this network make their judgments. In contrast with the idea of data as a rationalizing force, our study reveals that how data sources are selected and analyzed for judgments is very much shaped by the existing local and expert knowledge of policy advisors. The weight given to data is highly situational: we found that policy advisors welcome data in scoping the policy issue, but for judgments more closely connected to actual policy interventions, data are given limited value.
Carving at the Joints: Distinguishing Epistemic Wrongs from Epistemic Harms in Epistemic Injustice Contexts
Authors: Dunne Gerry , Kotsonis Alkis 
Published: January 2024

Abstract
This paper examines the relatively underexplored relationship between epistemic wrongs and epistemic harms in the context of epistemic injustice. Does the presence of one always imply the presence of the other? Or, is it possible to have one without the other? Here we aim to establish a prima facie case that epistemic wrongs do not always produce epistemic harms. We argue that the epistemic wrongness of an action should never be evaluated solely based on the action's consequences, viz. the epistemic and practical harms suffered by the wronged party. Instead – as we shall show – epistemic harms necessarily follow from epistemic wrongs. To conclude, we suggest ways in which extant accounts of epistemic wrongs and epistemic harms as they cash out in epistemic injustice contexts might be refined in light of our argument.
PL-Genus of surfaces in homology balls
Authors: Hom Jennifer , Stoffregen Matthew , Zhou Hugo 
Published: January 2024

Abstract
We consider manifold-knot pairs

$(Y,K)$

, where Y is a homology 3-sphere that bounds a homology 4-ball. We show that the minimum genus of a PL surface

$\Sigma $

in a homology ball X, such that

$\partial (X, \Sigma ) = (Y, K)$

can be arbitrarily large. Equivalently, the minimum genus of a surface cobordism in a homology cobordism from

$(Y, K)$

to any knot in

$S^3$

can be arbitrarily large. The proof relies on Heegaard Floer homology.
A HOMOMORPHISM BETWEEN BOTT–SAMELSON BIMODULES
Authors: ABE NORIYUKI 
Published: January 2024

AbstractIn the previous paper, we defined a new category which categorifies the Hecke algebra. This is a generalization of the theory of Soergel bimodules. To prove theorems, the existences of certain homomorphisms between Bott–Samelson bimodules are assumed. In this paper, we prove this assumption. We only assume the vanishing of certain two-colored quantum binomial coefficients.