bluuebunny/crossref_metadata_2025_split huggingface dataset:
Productions of X(3872), $$Z_c(3900)$$, $$X_2(4013)$$, and $$Z_c(4020)$$ in $$B_{(s)}$$ decays offer strong clues on their molecular nature
Authors: Wu Qi , Liu Ming-Zhu , Geng Li-Sheng 
Published: February 2024

AbstractThe exotic states X(3872) and $$Z_c(3900)$$

Z
c

(
3900
)

have long been conjectured as isoscalar and isovector $${\bar{D}}^*D$$

D

¯

∗

D

molecules. In this work, we first propose the triangle diagram mechanism to investigate their productions in B decays as well as their heavy quark spin symmetry partners, $$X_2(4013)$$

X
2

(
4013
)

and $$Z_c(4020)$$

Z
c

(
4020
)

. We show that the large isospin breaking of the ratio $${\mathcal {B}}[B^+ \rightarrow X(3872) K^+]/{\mathcal {B}}[B^0 \rightarrow X(3872) K^0] $$

B

[

B
+

→
X

(
3872
)

K
+

]

/
B

[

B
0

→
X

(
3872
)

K
0

]

can be attributed to the isospin breaking of the neutral and charged $${\bar{D}}^*D$$

D

¯

∗

D

components in their wave functions. For the same reason, the branching fractions of $$Z_c(3900)$$

Z
c

(
3900
)

in B decays are smaller than the corresponding ones of X(3872) by at least one order of magnitude, which naturally explains its non-observation. A hierarchy for the production fractions of X(3872), $$Z_c(3900)$$

Z
c

(
3900
)

, $$X_2(4013)$$

X
2

(
4013
)

, and $$Z_c(4020)$$

Z
c

(
4020
)

in B decays, consistent with all existing data, is predicted. Furthermore, with the factorization ansatz we extract the decay constants of X(3872), $$Z_c(3900)$$

Z
c

(
3900
)

, and $$Z_c(4020)$$

Z
c

(
4020
)

as $${\bar{D}}^*D^{(*)}$$

D

¯

∗

D

(

∗
)

molecules via the B decays, and then calculate their branching fractions in the relevant $$B_{(s)}$$

B

(
s
)

decays, which turn out to agree with all existing experimental data. The mechanism we proposed is useful to elucidate the internal structure of the many exotic hadrons discovered so far and to extract the decay constants of hadronic molecules, which can be used to predict their production in related processes.
High-efficiency Compressor Trees for Latest AMD FPGAs
Authors: Hoßfeld Konstantin , Damsgaard Hans Jakob , Nurmi Jar , Blott Michaela , Preußer Thomas B. 
Published: February 2024

High-fan-in dot product computations are ubiquitous in highly relevant application domains, such as signal processing and machine learning. Particularly, the diverse set of data formats used in machine learning poses a challenge for flexible efficient design solutions. Ideally, a dot product summation is composed from a carry-free compressor tree followed by a terminal carry-propagate addition. On FPGA, these compressor trees are constructed from generalized parallel counters whose architecture is closely tied to the underlying reconfigurable fabric. This work reviews known counter designs and proposes new ones in the context of the new AMD Versal™ fabric. On this basis, we develop a compressor generator featuring variable-sized counters, novel counter composition heuristics, explicit clustering strategies, and case-specific optimizations like logic gate absorption. In comparison to the Vivado™ default implementation, the combination of such a compressor with a novel, highly efficient quaternary adder reduces the LUT footprint across different bit matrix input shapes by 45% for a plain summation and by 46% for a terminal accumulation at a slight cost in critical path delay still allowing an operation well above 500 MHz. We demonstrate the aptness of our solution at examples of low-precision integer dot product accumulation units.
IDeSyDe: Systematic Design Space Exploration via Design Space Identification
Authors: Jordão Rodolfo , Becker Matthias , Sander Ingo 
Published: February 2024

Design space exploration (DSE) is a key activity in embedded design processes, where a mapping between applications and platforms that meets the process design requirements must be found. Finding such mappings is very challenging due to the complexity of modern embedded platforms and applications. DSE tools aid in this challenge by potentially covering sections of the design space that could be unintuitive to designers, leading to more optimised designs. Despite this potential benefit, DSE tools remain relatively niche in the embedded industry. A significant obstacle hindering their wider adoption is integrating such tools into embedded design processes.
We present two contributions that address this integration issue. First, we present the design space identification (DSI) approach for systematically constructing DSE solutions that are modular and tuneable. Modularity means that DSE solutions can be reused to construct other DSE solutions, while tuneability means that the most specific DSE solution is chosen for the target DSE problem. Moreover, DSI enables transparent cooperation between exploration algorithms. Second, we present IDeSyDe, an extensible DSE framework for DSE solutions based on DSI. IDeSyDe allows extensions to be developed in different programming languages in a manner compliant with the DSI approach.
We showcase the relevance of these contributions through five different case studies. The case study evaluations showed that non-exploration DSI procedures create overheads, which are marginal compared to the exploration algorithms. Empirically, most evaluations average 2% of the total DSE request. More importantly, the case studies have shown that IDeSyDe indeed provides a modular and incremental framework for constructing DSE solutions. In particular, the last case study required minimal extensions over the previous case studies so that support for a new application type was added to IDeSyDe.
Aqueous Extract of Leaves and Flowers of Acmella caulirhiza Reduces the Proliferation of Cancer Cells by Underexpressing Some Genes and Activating Caspase-3
Authors: Tienoue Fotso Huiny Miriane , Mbong Angie Mary-Ann , Ntentie Françoise Raïssa , Makamwe Inelle , Edoun Ebouel Ferdinand Lanvin , Kenjing Ndansack Emmerencia , Julius Oben Enyong 
Published: February 2024

The increasing prevalence of cancers and the multiple side effects of cancer treatments have led researchers to constantly search for plants containing bioactive compounds with cell death properties. This work aimed at evaluating the antiproliferative effect of an Acmella caulirhiza extract. After evaluation of the in vitro antioxidant potential of the three extracts of Acmella caulirhiza (aqueous (AE-Ac), hydroethanolic (HEE-Ac), and ethanolic (EE-Ac)) through the scavenging of DPPH● and NO● radicals, the extract with the best antioxidant activity was selected for bioactive compound assessment and antiproliferative tests. Subsequently, the cytotoxic activity was evaluated on the viability of breast (MCF-7), brain (CT2A, SB-28, and GL-261), colon (MC-38), and skin (YUMM 1.7 and B16-F1) cancer lines using the MTT method. Then, the line where the extract was the most active was selected to evaluate the expression of certain genes involved in cancerogenesis by RT-PCR and the expression of cleaved caspase-3 involved in cell death mechanism by western blot. The AE-Ac showed the best scavenging activity with IC50s of 0.52 and 0.02 for DPPH● and NO●, respectively. This AE-Ac was found to contain alkaloids, flavonoids, and tannins and was more active on YUMM 1.7 cells (IC50 = 149.42 and 31.99 μg/mL for 24 and 48 h, respectively). Results also showed that AE-Ac downregulated the expression of inflammation (IL-1b p=0.017 and IL-6 p=0.028), growth factors (PDGF p=0.039, IGF p=0.034, E2F1p=0.038, and E2F2p=0.016), and antiapoptotic protein genes (Bcl-2 p=0.028 and Bcl-6 p=0.039). The cleaved caspase-3 was positively modulated by the AE-Ac inducing thus cell death by apoptosis. AE-Ac showed inhibitory effects on the expression of genes involved in cancer progression making it a potential health intervention agent that can be exploited in cancer therapy protocols.
Is Thrombectomy Worth It for Isolated Posterior Cerebral Artery Occlusion? Meta‐Analysis and Trial Sequential Analysis
Authors: Jhou Hong‐Jie , Lee Cho‐Hao , Tsai Yu‐Chi , Chen Po‐Huang , Yang Li‐Yu 
Published: February 2024

Background
Thrombectomy is well‐established management for acute ischemic stroke involving large vessel occlusion. However. the potential efficacy of thrombectomy for isolated posterior cerebral artery occlusion remains limited. The study aims to evaluate the benefits of thrombectomy for isolated posterior cerebral artery occlusion.

Methods
We searched PubMed, Cochrane, and Embase for articles published until September 2023. The primary outcome was good functional outcome at 3 months. The secondary outcomes included excellent functional outcome at 3 months and early neurological improvement. The safety outcomes were symptomatic intracerebral hemorrhage, and mortality at 3 months.

Results
Seven retrospective studies involving 2560 patients with isolated posterior cerebral artery occlusion were included (876 patients receiving thrombectomy). The odds ratio (OR) of good functional outcome at 3 months was 0.93 (95% CI, 0.68–1.28) between 2 groups. The OR of excellent functional outcome (OR 1.23; 95% CI 0.92–1.64) and early neurological improvement (OR 1.82; 95% CI 0.97–3.40) were not different between the 2 groups. Compared with patients with best medical management, those with thrombectomy demonstrated a significantly increased risk of mortality (OR 1.81; 95% CI 1.24–2.65), whereas the risk of symptomatic intracerebral hemorrhage (OR 2.033; 95% CI 0.996–4.148) did not show an increase. Additionally, the results of trial sequential analysis indicated all outcomes were inconclusive.

Conclusion
Thrombectomy stands as an available procedure for patients with isolated posterior cerebral artery occlusion; however, it shows no notable benefits in reducing symptomatic intracerebral hemorrhage risk or enhancing function and may raise mortality compared with standard medical management. Further randomized controlled trials are necessary to yield more conclusive evidence.
Dynamic Impacts of Lockdown on Domestic Violence: Evidence from Multiple Policy Shifts in Chile
Authors: Bhalotra Sonia , Brito Emilia , Clarke Damian , Larroulet Pilar , Pino Francisco 
Published: February 2024

Abstract
We identify dynamic impacts on domestic violence (DV) of the staggered imposition and lifting of lockdown across Chile's 346 municipalities. Lockdown increases DV helpline calls and shelter occupancy without increasing DV police reports. These results are consistent with lockdown raising incidence and creating barriers to reporting. Once lockdown is lifted, shelter occupancy falls and police reports surge, but helpline calls remain elevated in line with state dependence in DV. We identify male job loss as a mechanism driving DV. Our findings accentuate controversy around welfare impacts of lockdown mandates. Adverse impacts of lockdown on DV are mitigated by cash transfers.
The Value of a High School GPA
Authors: Landaud Fanny , Maurin Éric , Willage Barton , Willén Alexander 
Published: February 2024

Abstract
This paper provides novel evidence on the causal effect of high school Grade Point Average (GPA) on the human capital development and labor market trajectory of individuals. Causal identification is achieved by exploiting a unique feature of the Norwegian education system that produces exogenous variation in GPA among high school students. We find little effect on the number of completed years of higher education, but significant effects on the number and quality of higher education programs available to students after high school. Most importantly, we find persistent effects on students' long-run labor market outcomes, most notably market wage.
Is Hybrid Work the Best of Both Worlds? Evidence from a Field Experiment
Authors: Choudhury Prithwiraj , Khanna Tarun , Makridis Christos A. , Schirmann Kyle 
Published: February 2024

Abstract
This paper reports causal evidence on how the extent of hybrid work—the number of days worked from home relative to days worked from office—affects employee attitudes and performance. Workers who spent around two days in the office each week on average self-reported greater work-life balance, more job satisfaction, and lower isolation from colleagues compared to workers who spent more or fewer days in the office. Employees in the intermediate hybrid condition received no different performance ratings compared to peers who spent more or fewer days in the office.
New records and potential distribution of Bufo luchunnicus (Yang & Rao, 2008) in Vietnam
Authors: Van Pham Anh , Le Minh Duc , Pham Cuong The , Ngo Hai Ngoc , Luu Vinh Quang , Sung Nenh Ba , Van Dau Trieu , Ziegler Thomas , Nguyen Truong Quang 
Published: February 2024

Abstract
The Luchun Stream Toad – Bufo luchunnicus (Yang and Rao, 2008) is a Critically Endangered species with a restricted distribution in southern China and northwestern Vietnam. Habitat loss and disturbance is the main threat to this species, but a lack of understanding of its natural history has hindered urgent conservation efforts to safeguard the species and its habitats. As a result of our field surveys, we herein report two new population records of B. luchunnicus in Vietnam and provide novel data on its natural history. In addition, species distribution models (MaxEnt – Maximum Entropy Algorithm) using current climatic data are applied to predict the potential distribution of B. luchunnicus.
Vulnerability of Female Headed Households
Authors: Al Fara Heba 
Published: February 2024

Abstract
Research has shown that the vulnerability of female headed households is hugely exacerbated during crises such as wars and conflict. However, little research has uncovered the unique challenges that single women face in accessing humanitarian aid, for themselves and for their dependents, before, during and immediately following a crisis. This article critically examines the challenges that female headed households face in accessing humanitarian aid in crisis settings to provide a clearer and deeper understanding as well as exploration of the risks. This research found that although social and cultural health but also logistical as well as economic challenges limit female headed households’ access to humanitarian aid, female heads of households use their agency to actively respond to these challenges to provide for their dependents during a crisis. Thus, female headed households must be recognized as active agents prior to, during and immediate post conflict situations and must be supported socially, politically and economically, using effective, sustainable and equitable techniques.
Effect of Missed Post-Procedure Creatinine Measurement on Sub-Acute Kidney Injury Following Coronary Angiography
Authors: Lu Xiaozhao , Li Qiang , Chen Weihua , Deng Jingru , Shi Shanshan , Huang Haozhang , Liang Guoxiao , Huang Zhidong , Lin Xueqin , Deng Jiayi , Chen Jiyan , Liu Jin , Liu Yong 
Published: February 2024

Serum creatinine (SCr) levels are essential for the diagnosis of kidney disease after coronary angiography (CAG). However, the influence of missed post-procedure SCr measurement in this situation is unclear. The present study included 14,127 patients undergoing CAG as part of the Cardiorenal ImprovemeNt registry II. Patients were divided into two groups according to whether a post-procedure SCr was measured within 3 days. The primary endpoint was acute kidney disease (AKD). Logistic regression was used to evaluate the relationship between post-procedure SCr and AKD. Of the 14,127 patients (61.6 ± 9.8 years, 34.2% females), 55.4% ( n = 7822) did not have a post-procedure SCr measurement. The incidence of AKD was higher in the missed post-procedure SCr group (15.7 vs 11.9%; median follow-up 6.54 years). Multivariate logistic regression showed that missed post-procedure SCr measurement was associated with significantly higher risk of AKD (adjusted odds ratio [aOR]: 1.26, 95% CI: 1.10–1.45, P < .001). The results were more significant in patients with normal renal function at baseline (aOR: 1.36, 95% CI: 1.16–1.60, P < .001). In our study, over half of the patients undergoing CAG missed their post-procedure SCr measurement. The missed post-procedure SCr group had a significantly higher risk of developing AKD compared with those with a post-procedure SCr measurement.
Optimizing Concussion Care Seeking: Connecting Care-Seeking Behaviors and Neurophysiological States Through Blood Biomarkers
Authors: D’Lauro Christopher , Register-Mihalik Johna K. , Meier Timothy B. , Kerr Zachary Yukio , Knight Kristen , Broglio Steven P. , Leeds Daniel , Lynall Robert C. , Kroshus Emily , McCrea Michael A. , McAllister Thomas W. , Schmidt Julianne D. ,   CARE Consortium Investigators:, Master Christina , McGinty Gerald , Jackson Jonathan C. , Cameron Kenneth L. , Buckley Thomas , Kaminski Thomas , Mihalik Jason P. 
Published: February 2024

Background: Timely and appropriate medical care after concussion presents a difficult public health problem. Concussion identification and treatment rely heavily on self-report, but more than half of concussions go unreported or are reported after a delay. If incomplete self-report increases exposure to harm, blood biomarkers may objectively indicate this neurobiological dysfunction. Purpose/Hypothesis: The purpose of this study was to compare postconcussion biomarker levels between individuals with different previous concussion diagnosis statuses and care-seeking statuses. It was hypothesized that individuals with undiagnosed concussions and poorer care seeking would show altered biomarker profiles. Study Design: Cohort study; Level of evidence, 3. Methods: Blood samples were collected from 287 military academy cadets and collegiate athletes diagnosed with concussion in the Advanced Research Core of the Concussion Assessment, Research and Education Consortium. The authors extracted each participant’s self-reported previous concussion diagnosis status (no history, all diagnosed, ≥1 undiagnosed) and whether they had delayed or immediate symptom onset, symptom reporting, and removal from activity after the incident concussion. The authors compared the following blood biomarkers associated with neural injury between previous concussion diagnosis status groups and care-seeking groups: glial fibrillary acidic protein, ubiquitin c-terminal hydrolase-L1 (UCH-L1), neurofilament light chain (NF-L), and tau protein, captured at baseline, 24 to 48 hours, asymptomatic, and 7 days after unrestricted return to activity using tests of parallel profiles. Results: The undiagnosed previous concussion group (n = 21) had higher levels of NF-L at 24- to 48-hour and asymptomatic time points relative to all diagnosed (n = 72) or no previous concussion (n = 194) groups. For those with delayed removal from activity (n = 127), UCH-L1 was lower at 7 days after return to activity than that for athletes immediately removed from activity (n = 131). No other biomarker differences were observed. Conclusion: Individuals with previous undiagnosed concussions or delayed removal from activity showed some different biomarker levels after concussion and after clinical recovery, despite a lack of baseline differences. This may indicate that poorer care seeking can create neurobiological differences in the concussed brain.
Nano-clay treatment of jute fiber for reinforcement in polymer composites: Mechanical, morphological, and thermo-kinetic analysis
Authors: Yadav Brijesh Kumar , Yadav Vijay Laxmi 
Published: February 2024

Natural fibers have demonstrated exceptional properties that can be utilized as a viable and environmentally reliable material for reinforcement in polymer composites replacing their synthetic counterparts creating numerous environmental problems. Jute fiber is a prominent natural fiber that has been successfully applied for manufacturing noble natural fiber-based composites. This article describes the advantages and comparison between two surface treatment techniques that is alkali treatment and nano-clay treatment of jute fiber to enhance the properties for producing improved composite material. FTIR, SEM, AFM, and TGA have been utilized to compare and study how different surface treatment methods affect jute fiber. Isoconversional methods FWO and KAS are applied for the thermos-kinetic analysis and evaluation of activation energy of thermal decomposition. More than 30% increase in peak activation energy has been observed (120 KJ/mole to 160 KJ/mol). Alkali–nano-clay treated jute fiber exhibits nearly 32% improvement (405 MPa to 535 MPa) in tensile strength, 24% increment (11.85 GPa to 14.69 GPa) in tensile modulus, and 15% improvement (1.4 gm/cm3 to 1.61 gm/cm3) in fiber density as compared to that of untreated jute fiber. This study validates that nano-clay treatment has shown promising results and can improve the overall properties of natural fibers significantly.
A Systematic Review of Dementia Research Priorities
Authors: Ghosh Manonita , Chejor Pelden , Baker Melanie , Porock Davina 
Published: February 2024

Introduction Patient involvement is a critical component of dementia research priority-setting exercises to ensure that research benefits are relevant and acceptable to those who need the most. This systematic review synthesises research priorities and preferences identified by people living with dementia and their caregivers. Methods Guided by Joanna Briggs Institute methodology, and Preferred Reporting Items for Systematic Reviews and Meta-Analyses framework, we conducted a systematic search in five electronic databases: CINAHL, Medline, PsycINFO, Web of Science and Scopus. The reference lists of the included studies were also manually searched. We combined quantitative and qualitative data for synthesis and descriptive thematic analysis. Results Eleven studies were included in this review. Findings are grouped into four main categories: Increase in knowledge, education, and awareness; Determining the cause; Sustainability of care; and Cure of dementia and related conditions. Conclusion There is a need to respond to the stigma associated with dementia, which limits access to care and the quality of life for both people living with dementia and their caregivers. We need to work on changing public, private and workplace attitudes about dementia and encourage supporting and participating in dementia research. Future research should involve people living with dementia and their primary caregivers from culturally and linguistically diverse communities in priority-setting exercises.
Bio-based flame retardants containing a biphenyl unit for enhancing mechanical properties and fire safety of epoxy resins
Authors: Ren Bin , Wang Chenchen , Ma Rui , Huang Ying , Li Xiuyun 
Published: February 2024

A reactive flame retardant containing biphenyl structure (DEU-2DOPO) was prepared from the bio-based raw material eugenol. The incorporation of DEU-2DOPO into the epoxy resin serves to enhance the ring-opening reaction of the epoxy. Furthermore, the inclusion of DEU-2DOPO has been found to have a positive impact on the glass transition temperature and residual carbon rate of the epoxy resin. This additive also significantly improves the mechanical properties of the epoxy resin, leading to a 49.3% increase in tensile strength, an 81.9% increase in breaking elongation, and a 15.8% increase in flexural strength. Notably, when DEU-2DOPO is introduced at a concentration of 5 wt%, it not only achieves a V-0 rating in the UL-94 test but also exhibits an impressive ultimate oxygen index of 34.5%. Additionally, the cone calorimetric testing revealed that the presence of DEU-2DOPO results in lower combustion metrics compared to pure epoxy, as evidenced by a reduction of 15.1% in total heat release (THR) and 10.8% in total smoke release (TSR). An analysis of the flame retardant mechanism elucidates that DEU-2DOPO promotes the formation of a stable and dense residual carbon, thereby impeding gas and heat exchange. Furthermore, the decomposition of DEU-2DOPO generates PO· and PO2· radicals, which effectively neutralize reactive radicals.