bluuebunny/crossref_metadata_2025_split huggingface dataset:
Observation of Topological Hall Effect in a Chemically Complex Alloy
Authors: Yu Jihao , Liu Yuying , Ke Yubin , Su Jiaqi , Cao Jingshan , Li Zian , Sun Baoan , Bai Haiyang , Wang Weihua 
Published: January 2024

AbstractThe topological Hall effect (THE) is the transport response of chiral spin textures and thus can serve as a powerful probe for detecting and understanding these unconventional magnetic orders. So far, the THE is only observed in either noncentrosymmetric systems where spin chirality is stabilized by Dzyaloshinskii–Moriya interactions, or triangular‐lattice magnets with Ruderman–Kittel–Kasuya–Yosida‐type interactions. Here, a pronounced THE is observed in a Fe‐Co‐Ni‐Mn chemically complex alloy with a simple face‐centered cubic (fcc) structure across a wide range of temperatures and magnetic fields. The alloy is shown to have a strong magnetic frustration owing to the random occupation of magnetic atoms on the close‐packed fcc lattice and the direct Heisenberg exchange interaction among atoms, as evidenced by the appearance of a reentrant spin glass state in the low‐temperature regime and the first principles calculations. Consequently, THE is attributed to the nonvanishing spin chirality created by strong spin frustration under the external magnetic field, which is distinct from the mechanism responsible for the skyrmion systems, as well as geometrically frustrated magnets.
Application of Solid Me3SiZnI for the Synthesis of Aryl and Alkyl Trimethylsilanes
Authors: Ganguly Anirban , Chandrasekaran Revathi , Balamurugan Bala S. S. , Rasappan Ramesh 
Published: January 2024

AbstractSilylzinc reagents are desirable for the synthesis of organosilanes due to their compatibility with functional groups; however, the use of pyrophoric silyllithium and dissolved lithium salts in their production hinders their development. Our solid Me3SiZnI circumvents these limitations, and herein, we demonstrate its significance in the synthesis of aryl and alkyl trimethylsilanes via cross‐coupling of aryl and alkyl bromides. The milder reaction condition tolerates functional groups such as MOM, Boc, Bpin, and aldehydes.
Correlation between inflammatory biomarkers and disease control in chronic rhinosinusitis with nasal polyps
Authors: De Corso Eugenio , Baroni Silvia , Settimi Stefano , Onori Maria Elisabetta , di Cesare Tiziana , Mastrapasqua Rodolfo Francesco , Sarlo Francesca , Penazzi Daniele , D'Agostino Giuseppe , D'Auria Leandro Maria , De Maio Gabriele , Fetoni Anna Rita , Galli Jacopo 
Published: January 2024

AbstractBackgroundChronic rhinosinusitis with nasal polyps (CRSwNP) may have a heterogeneous response to medical/surgical treatments based on endotypes. Data correlating biomarkers and severity of the disease are lacking. We aimed to determine if IL‐5 and calprotectin may be useful in defining severity of disease and identifying uncontrolled patients.MethodsThis was a case–control study including 81 patients with diffuse CRSwNP who underwent at least one previous surgery and treated with intranasal steroids. We enrolled 39 uncontrolled patients (SNOT‐22 ≥ 40 and two or more cycles of systemic corticosteroids in last year) (Group A) and 42 controlled one (SNOT‐22 < 40 and less than two cycles of systemic corticosteroids in last year) (Group B). We analyzed IL‐5 and calprotectin in both nasal secretions and nasal polyp tissue.ResultsCalprotectin and IL‐5 were significantly higher in Group A in both secretions and tissue, and the higher the number of previous surgeries, the higher the levels detected in nasal secretions. At univariate analyses, smoking, asthma, non‐steroidal anti‐inflammatory drugs‐exacerbated respiratory disease (NSAID‐ERD), blood eosinophilia, neutrophils, and eosinophils at nasal cytology were significantly associated with uncontrolled disease. Multivariate analyses showed that asthma, NSAID‐ERD, and IL‐5 in nasal secretion/polyp tissue were significantly related to the risk of uncontrolled disease.ConclusionsOur data suggest that asthma, NSAID‐ERD, and IL‐5 in nasal secretions/tissue may be helpful to identify more severe patients, as they are related to the risk of uncontrolled disease. Nonetheless, high levels of calprotectin and neutrophilia were also observed in uncontrolled patients, especially after multiple surgeries.
Seed‐Induced Living Two‐Dimensional (2D) Supramolecular Polymerization in Water: Implications on Protein Adsorption and Enzyme Inhibition
Authors: Khanra Payel , Rajdev Priya , Das Anindita 
Published: January 2024

AbstractIn biological systems, programmable supramolecular frameworks characterized by coordinated directional non‐covalent interactions are widespread. However, only a small number of reports involve pure water‐based dynamic supramolecular assembly of artificial π‐amphiphiles, primarily due to the formidable challenge of counteracting the strong hydrophobic dominance of the π‐surface in water, leading to undesired kinetic traps. This study reveals the pathway complexity in hydrogen‐bonding‐mediated supramolecular polymerization of an amide‐functionalized naphthalene monoimide (NMI) building block with a hydrophilic oligo‐oxyethylene (OE) wedge. O‐NMI‐2 initially produced entropically driven, collapsed spherical particles in water (Agg‐1); however, over a span of 72 h, these metastable Agg‐1 gradually transformed into two‐dimensional (2D) nanosheets (Agg‐2), favoured by both entropy and enthalpy contributions. The intricate self‐assembly pathways in O‐NMI‐2 enable us to explore seed‐induced living supramolecular polymerization (LSP) in water for controlled synthesis of monolayered 2D assemblies. Furthermore, we demonstrated the nonspecific surface adsorption of a model enzyme, serine protease α‐Chymotrypsin (α‐ChT), and consequently the enzyme activity, which could be regulated by controlling the morphological transformation of O‐NMI‐2 from Agg‐1 to Agg‐2. We delve into the thermodynamic aspects of such shape‐dependent protein‐surface interactions and unravel the impact of seed‐induced LSP on temporally controlling the catalytic activity of α‐ChT.
Designing Metal–Organic Framework (MOF) Membranes for Isomer Separation
Authors: Cong Shenzhen , Zhou Yunqi , Luo Chenglian , Wang Caixia , Wang Jixiao , Wang Zhi , Liu Xinlei 
Published: January 2024

AbstractMembrane‐based separation has the merit of low carbon footprint. In this study, the pore size of metal–organic framework (MOF) membranes is rationally designed for discriminating various pairs of hydrocarbon isomers. Specifically, Zr‐MOF UiO‐66 (UiO stands for University of Oslo) membranes are developed for separating p/o‐xylene due to their proper pore size. For n‐hexane/2‐methylpentane separation, the functional groups and proportion of the ligands in UiO‐66 are gradually adjusted to effectively regulate the pore size, and UiO‐66‐33Br membranes are constructed. In addition, relying on the utilization of ligands with shorter length, MOF‐801 membranes with smaller pore size are fabricated for n/i‐butane separation.
Leader‐following distributed control of networked linear multi‐input systems: A prescribed‐time framework
Authors: Zhang Pengfei , Yang Tingting 
Published: January 2024

AbstractThis paper concentrates on the leader‐following distributed control problem for linear multi‐input systems while guaranteeing prescribed finite‐time performance. Compared with the current state of the arts, novel nonsingular coordinate transformations are proposed by using the block decomposition technique and smooth time‐varying scaling functions, such that a prescribed‐time control framework dealing with distinct subsystem dimensions featured by multi‐input systems is acquired. The prescribed‐time boundedness of the closed‐loop system and the control input is proven by introducing nonsingular inverse coordinate transformations. Moreover, the settling time can relax the initial conditions and any other control parameters. Numerical examples are provided to confirm the efficacy of the proposed method.
Brandversuch an einer begrünten Holzaußenwandbekleidung
Authors: Westphal Robert , Zauper Linda , Trautmann Benjamin , Pedrotti Dina , Gietmann Ansgar R. 
Published: January 2024

AbstractDer Anteil begrünter Gebäudehüllen wächst seit einigen Jahren stetig. Neben der temperaturregulierenden Eigenschaft, der akustisch dämpfenden Wirkung und der Bindung von Feinstaub tragen Fassadenbegrünungen zu einem harmonischen Stadtbild bei. Gleichzeitig wird auch der Holzbau zunehmend etabliert, sodass eine Kombination beider Systeme im Sinne einer nachhaltigen Bauweise zielführend erscheint. Bislang sind keine Ergebnisse von Brandversuchen an einer begrünten Holzfassade in der Literatur beschrieben. Zur orientierenden Einschätzung des Brandverhaltens wurde daher ein Fassadenbrandversuch in Anlehnung an DIN 4102‐20 durchgeführt. Hierfür wurde entsprechend der Muster‐Holzbaurichtlinie eine Musterfassade als geschlossene und hinterlüftete Holzaußenwandbekleidung mit Brandsperren an einem Prüfstand errichtet. Als flächige, bodengebundene Begrünung wurden Kiwi (Actinidia arguta Geneva) und Kriechspindel (Euonymus fortunei Coloratus) an einem vorgesetzten Rankgerüst untersucht. Als wesentliche Erkenntnis wurde festgestellt, dass die vorgesetzte Fassadenbegrünung nicht zu einer unkontrollierten vertikalen Brandausbreitung auf der Holzaußenwandbekleidung führte. Die brennende Holzaußenwandbekleidung entzündete mehrmals die Begrünung, die brennende Begrünung aber nie die Holzaußenwandbekleidung. Es konnte keine beschleunigte Brandausbreitung auf der Holzaußenwandbekleidung beobachtet werden. Die Brandsperren der Holzaußenwandbekleidung behielten ausreichend lang ihre Funktion.
Groups or values? Testing the effectiveness of online social cure, group‐affirmation, and self‐affirmation manipulations on wellbeing outcomes
Authors: Harris Peter R. , Easterbrook Matthew J. 
Published: January 2024

AbstractWe tested the effectiveness of three brief, online manipulations theorised to have beneficial effects on wellbeing: a social cure manipulation priming important group memberships, a self‐affirmation manipulation priming important values, and a group‐affirmation manipulation priming values important to one's group. A control condition required respondents to reflect on films. Study 1 (N = 201) had no explicit stressor, whereas study 2 (N = 379) had an acute stressor immediately before the manipulations. The outcomes were a set of hedonic, evaluative, and eudaimonic wellbeing measures. With no acute stressor, all three manipulations boosted wellbeing perceptions, but in diverse ways. After a stressor, the social cure manipulation was the most frequent predictor. In all cases, main effects of the manipulations boosted wellbeing perceptions; however, where effects were moderated by baseline anxiety or stress induced by the stressor, the benefits were restricted to those lower in anxiety and stress. Overall, the results lend support to the idea that brief online manipulations, especially ones priming collective identities, can be beneficial for wellbeing. Please refer to the Supplementary Material section to find this article's Community and Social Impact Statement.
Endolysosomal two‐pore channel 2 plays opposing roles in primary and metastatic malignant melanoma cells
Authors: Barbonari Samantha , D'Amore Antonella , Hanbashi Ali A. , Palombi Fioretta , Riccioli Anna , Parrington John , Filippini Antonio 
Published: January 2024

AbstractThe ion channel two‐pore channel 2 (TPC2), localised on the membranes of acidic organelles such as endo‐lysosomes and melanosomes, has been shown to play a role in pathologies including cancer, and it is differently expressed in primary versus metastatic melanoma cells. Whether TPC2 plays a pro‐ or anti‐oncogenic role in different tumour conditions is a relevant open question which we have explored in melanoma at different stages of tumour progression. The behaviour of primary melanoma cell line B16F0 and its metastatic subline B16F10 were compared in response to TPC2 modulation by silencing (by small interfering RNA), knock‐out (by CRISPR/Cas9) and overexpression (by mCherry‐TPC2 transfected plasmid). TPC2 silencing increased cell migration, epithelial‐to‐mesenchymal transition and autophagy in the metastatic samples, but abated them in the silenced primary ones. Interestingly, while TPC2 inactivation failed to affect markers of proliferation in both samples, it strongly enhanced the migratory behaviour of the metastatic cells, again suggesting that in the more aggressive phenotype TPC2 plays a specific antimetastatic role. In line with this, overexpression of TPC2 in B16F10 cells resulted in phenotype rescue, that is, a decrease in migratory ability, thus collectively resuming traits of the B16F0 primary cell line. Our research shows a novel role of TPC2 in melanoma cells that is intriguingly different in initial versus late stages of cancer progression.
LRP8 promotes tumorigenesis in ovarian cancer through inhibiting p53 signaling
Authors: Xu Yan , Zhou Yang , Yi Xiling , Nie Xiaocui 
Published: January 2024

AbstractOvarian cancer (OC) is the most lethal gynecological malignancy with a high mortality rate. Low‐density lipoprotein (LDL) receptor‐related protein 8 (LRP8) is a cell membrane receptor belonging LDL receptor family and is involved in several tumor progressions. However, there is limited understanding of how LRP8 mediates OC development. LRP8 expression level was identified in human OC tissues and cells using immunohistochemical staining and quantitative polymerase chain reaction assays, respectively. Functions of LRP8 in OC progression were evaluated by Celigo cell counting, wound healing, transwell and flow cytometry assays, and the xenograft models. The human phospho‐kinase array analysis was used for screening potential signaling involved in OC development. We observed that LRP8 was overexpressed in OC tissues, and high expression of LRP8 was associated with poor prognosis of OC patients. Functionally, LRP8 knockdown remarkably reduced proliferation and migration of OC cells, and induced apoptosis and S phase cycle arrest. LRP8 deficiency attenuated in vivo tumor growth of OC cells. Moreover, the addition of p53 inhibitor partially reversed the effects of LRP8 knockdown on OC cell proliferation and apoptosis, indicating the involvement of p53 signaling in LRP8‐mediated OC progression. This study confirmed that LRP8/p53 axis contributed to OC progression, which might serve as a novel potential therapeutic target for OC patients.
Way of life: A future research agenda for how worldviews impact financial attitudes and behaviors
Authors: Enete Shane , McDowell Sean 
Published: January 2024

AbstractThe purpose of this paper is to provide a future research agenda to study how worldviews impact financial attitudes and behaviors. In addition, this paper will help operationalize many of the constructs associated with an individual's values and personal worldview. As a result of this research agenda, researchers and financial planners will move towards developing personal value and worldview identification tools that will help individuals more intrinsically adopt savings goals that help meet their life goals.
A robust neural network model for fault detection in the presence of mislabelled data
Authors: Alauddin Mohammad , Khan Faisal , Imtiaz Syed , Ahmed Salim , Amyotte Paul 
Published: January 2024

AbstractSeveral data‐driven methodologies for process monitoring and detection of faults or abnormalities have been developed for the safety of processing systems. The effectiveness of data‐based models, however, is impacted by the volume and quality of training data. This work presents a robust neural network model for addressing the mislabelled and low‐quality data in detecting faults and process abnormalities. The approach is based on harnessing data quality features along with supervisory labels in the network training. The data quality has been computed using the Mahalanobis distances and trusted centres of each class of data such as normal and faulty data. The method has been examined for detecting abnormalities in two case studies; a continuous stirred tank heater problem for detecting leaks and the Tennessee Eastman chemical process for detecting step and sticking faults. The performance of the proposed robust artificial neural networks (ANN) model is evaluated in terms of accuracy, fault detection rate, false alarm rate, and classification index at varying extents of mislabelling, namely, 1%, 5%, and 10% mislabelled data. The proposed model demonstrates higher detection performance, especially at increased labels of mislabelled data where the performance of the conventional ANN is severely impacted. The proposed methodology can be advantageous in handling mislabelled and low‐quality data issues which are crucial in the data‐driven modelling of processing systems.
The drive and passion of Faisal Khan to improve onshore and offshore process industries' safety levels
Authors: Pasman Hans , Amin Md Tanjin 
Published: January 2024

AbstractIn 1997, a number of articles were co‐authored and published in leading process safety journals (e.g., Journal of Loss Prevention in the Process Industries, Process Safety Progress, and Process Safety and Environmental Protection) by a young and enthusiastic scientist, Faisal Khan—motivated by a drive to improve the safety practices of the time after the 1984 Bhopal Disaster—and a well‐known Professor and Scientist from the Centre for Pollution Control and Environmental Engineering at Pondicherry University, Dr. Shahid Abbas Abbasi. It began a new horizon in the process safety domain, as this young scientist continued to excel in this field and shed light with numerous inventions and by training several hundreds of next‐generation safety professionals as a Professor at Memorial University of Newfoundland, University of Tasmania, and Texas A&M University. This article is written in honour of Dr. Faisal Khan. Capturing the fullness of Dr. Khan briefly is an arduous task; however, the authors of the current article have attempted to describe his personality, background, and contributions based on their professional interactions with him.
Artemsieverolactones A—H, Eight Guaiane‐Type Sesquiterpenoid Trimers from Artemisia sieversiana
Authors: Dong Wei , Huang Xiao‐Yan , Li Tian‐Ze , Weng Yan‐Mei , Geng Chang‐An , Chen Ji‐Jun 
Published: January 2024

Comprehensive SummaryEight new guaiane‐type sesquiterpenoid trimers, artemsieverolactones A—H, possessing unprecedented scaffolds via biocatalyzed [4+2] Diels−Alder cycloaddition reactions were identified from Artemisia sieversiana. Their structures were determined by comprehensive spectroscopic data, single‐crystal X‐ray diffraction analyses, and ECD calculations. In terms of structure, artemsieverolactones A—H are first examples of sesquiterpenoid trimers from guaiane‐type sesquiterpenoid through four different [4+2] Diels−Alder cycloaddition models. Antihepatic fibrosis assay suggested that five compounds exhibited activity against HSC‐LX2 with IC50 values ranging from 37.8 to 117.1 μmol/L. The most active artemsieverolactone B (2) displayed significant inhibitory activity against HSC‐LX2 with IC50 value of 37.8 μmol/L, which was 3 times more active than the positive drug silybin (IC50, 139.7 μmol/L). Preliminary mechanism study revealed that artemsieverolactone B could inhibit the deposition of human collagen type I (Col I), human hyaluronic acid (HA), and human laminin (HL) with IC50 values of 40.4 μmol/L (Col I), 55.1 μmol/L (HL), 47.3 μmol/L (HA), which was 2 to 3‐fold more potent than silybin.
Intermittent investigations on attenuation mechanism of rechargeable zinc‐air batteries during charge/discharge cycles
Authors: Peng Qiuyue , Chen Zhaotian , Zhang Yiwen , Geng Zirui , Wang Lilan , Dong Xinyao , Wang Juan , Zhong Qin 
Published: January 2024

AbstractRechargeable zinc‐air batteries (RZABs) are an ideal substitute for energy storage, but the short cycle longevity during long‐term charge/discharge operation is one of the bottleneck factors that seriously restrict commercial application. Herein, the FeCo alloy/N, S co‐doped carbon aerogel (NSCA/FeCo) were prepared as catalysts of cathode for RZABs. We investigated the polarization and impedance on long‐term cycles during the battery operation to explore the attenuation mechanism. The results indicated that the roundtrip efficiency of batteries during charge/discharge cycles reduced fast initially and then slow. Besides, the comparative experiment was tested through the replacement of a new electrolyte and a zinc sheet. It is manifested that the failure of the battery is mainly due to the attenuation of the air cathode performance. Therefore, to further disclose the influencing factors and internal mechanisms of air cathode performance degradation, we conducted a series of characterization and testing, including the hydrophilicity, surface morphology, elemental composition, and electrochemical performance of three‐electrode systems at different cycle times. This work not only provides a theoretical basis for deeply comprehending the attenuation mechanism of the cathode but also serves a reference for the material design and operating condition optimization of RZABs.
Building Trust in AI Farming Tools
Authors: Joosse Tess 
Published: January 2024

AbstractPrecision agriculture tools like decision support systems increasingly use machine‐learning algorithms and other types of artificial intelligence (AI) to analyze large quantities of agricultural data and provide recommendations to producers and crop advisers. However, several barriers threaten adoption of these tools. Three papers in the recent Agronomy Journal special section, “Machine Learning in Agriculture,” explore this phenomenon and offer solutions and opportunities for building trust in these technologies.
An E band MMIC power amplifier design using 100 nm T‐Gate GaN HEMT on SiC
Authors: Jin Liwei , Cheng Zhiqun , Wang Yonghui , Liu Guohua 
Published: January 2024

SummaryThe small signal modeling, design, fabrication, and measurement about monolithic millimeter‐wave integrated circuit (MMIC) using gallium nitride (GaN) power amplifier (PA) on silicon carbide (SiC) working at the E band are proposed in this paper. The two stage PA used customized 4 × 75 μm transistor with 100 nm T gate technology. The extraction and optimization of small signal model are based on single GaN high electron mobility transistor (HEMT)'s measurement. Balanced structure and new method are used by low impedance matching, which can simplify circuits prominently and benefit for die size reduction. Radial stub and LC stub are made the whole circuit in absolute stable status; the in‐series DC block metal–insulator–metal capacitor from the matching circuit ensure the process is within small tolerances. From the 61–66 GHz bandwidth, a peak 10.7 dB small signal gain is obtained from the designed MMIC GaN PA, and also, the maximum output power can reach 29.7 to 30.4 dBm from 61 to 66 GHz, with an associated the peak drain efficiency of 18.8%. The final die size without dicing slot is 3.0 × 1.74 mm2.
Electron acceleration in a warm, motional, magnetized plasma‐filled waveguide by twisted electromagnetic wave pulses
Authors: Barzegar B. , Hasanbeigi A. , Mehdian H. , Hajisharifi K. 
Published: January 2024

AbstractThis paper studies the acceleration of an electron in a magnetized plasma waveguide caused by the interaction between the twisted electromagnetic wave and the plasma wave in a motional plasma. The spatial dependence of the amplitude and phase of the twisted TM mode has been derived by solving the wave equation. With appropriately assigned initial values, total electron energy gain can be calculated using numerical calculations. Numerical results show that plasma motion, as long as the twisted electromagnetic wave pulse, significantly affects electron acceleration during an electron's passage through the waveguide.