bluuebunny/crossref_metadata_2025_split huggingface dataset:
Different Managements of the same disease- Malignant Ovarian Germ Cell Tumor Treated by Pediatric or Gynecologic Oncologists
Authors: Lin Wen-Hsuan , Yeh Ting-Chi , Liu Hsi-Che , Hou Jen-Yin , Chang Chih-Long 
Published: October 2023

Abstract
Objective The surgical approach, staging system, including the criteria for adjuvant chemotherapy and even the chemotherapeutic regimens between Pediatric and Gynecologic oncologists are different for a same disease- malignant ovarian germ cell tumors (MOGCTs). This study is to review the differences with regard to the survival and re-appraise each mode of treatment.Methods A retrospective review of medical records of the patients with malignant germ cell tumor in Mackay Memorial Hospital between 1997 ~ 2017 were performed. We re-staged the patients in pediatric group from COG stage system to FIGO stage system and documented the disease survival rate in different staging system. Accordingly, treatment outcomes were compared by progression-free survival rate, using Kaplan-Meier method.Results 87 patients with MOGCTs were analyzed. 67 cases are managed by Gynecologist and 20 cases by Pediatrician. There was no significant differences of the progression-free survival rate at 10 years in patients with conservative surgery or fertility-sparing staging operation (p = 0.747). Ten-year progression free survival rate in patient receiving chemotherapy with BEP regimen (bleomycin + etoposide + cisplatin) was 97.8% and in JEB regimen (bleomycin + etoposide + carboplatin) was 77.8% (p = 0.0076).Conclusion The survival rates are similar between patients receiving conservative surgical approach or complete staging operation. It might be due to the high chemosensitivity nature of these diseases. However, our data suggest cisplatin is more effective than carboplatin in high-risk group.
Ultrastrong exciton-plasmon couplings in WS2 multilayers synthesized with a random multi-singular metasurface at room temperature
Authors: Luo Yu , Wu Tingting , Wang Chongwu , Hu Guangwei , Wang Zhixun , Zhao Jiaxin , Wang Zhe , Chaykun Ksenia , Liu Lin , Chen Mengxiao , Li Dong , Xiong Qihua , Shen Ze , Gao Huajian , Garcia-Vidal Francisco , Wei Lei , Wang Qi jie 
Published: October 2023

Abstract
Van der Waals semiconductors exemplified by two-dimensional transition-metal dichalcogenides have promised next-generation atomically thin optoelectronics. Boosting their interaction with light is vital for practical applications, especially in the quantum regime where ultrastrong coupling is highly demanded but not yet realized. Here we report ultrastrong exciton-plasmon coupling at room temperature in tungsten disulfide (WS2) layers loaded with a random multi-singular plasmonic metasurface deposited on a flexible polymer substrate. Different from seeking perfect metals or high-quality resonators, we create a unique type of metasurface with a dense array of singularities that can support nanometre-sized plasmonic hotspots to which several WS2 excitons coherently interact. The associated normalized coupling strength is 0.12 for monolayer WS2 and can be up to 0.164 for quadrilayers, showcasing the ultrastrong exciton-plasmon coupling and important for practical optoelectronic devices based on low-dimensional semiconductors.
In Vitro Induction of Polyploidy by Colchicine in the Protocorm of the Orchid Dendrobium wardianum Warner
Authors: Wang Fei , Zhuo Xiaokang , Arslan Muhammad , Ercisli Sezai , Chen Jinliao , Liu Zhongjian , Lan Siren , Peng Donghui 
Published: October 2023

Dendrobium wardianum is a key ornamental plant and a valuable traditional Chinese medicine. This research aimed to find the optimal protocol for in vitro inducement of polyploidy in D. wardianum by treating protocorms with colchicine (an antimitotic agent). The experiment consisted of two series of treatments. For the first treatment, the protocorms were subjected to colchicine concentrations of 25, 75, 125, 250, and 500 μM (weight/volume) for 6, 12, and 24 hours. For the second treatment, protocorms were cultivated in culture medium with colchicine (25, 75, 125, and 250 μM) for 30 days. A total of 18 polyploids were confirmed by chromosome counts and anatomical parameters. Polyploids had broad, dark green leaves with increased stem lengths compared with those of diploids. The optimal protocol for these two methods consisted of soaking in 250 μM of colchicine solution for 12 hours, resulting in inductivity of 26%, and cultivating in 75 μM for 30 days, resulting in a mutation rate of 34%. A comparison of these two protocols showed that the latter one induced more stable polyploids, but that the survival rate was slightly lower. The survival and induced mutation rates of these plants were significantly influenced by the colchicine concentration and exposure time. Higher concentrations for longer periods of time resulted in greater mortality rates and longer-lasting side effects. The protocol involving a solid medium and colchicine is worth considering. It will be intriguing to examine this methodology for the induction of stable polyploids of other orchid species.
Application of machine learning techniques for obesity prediction: a comparative study
Authors: Dirik Mahmut 
Published: October 2023

Obesity, characterized by excess adipose tissue, is becoming a major public health problem. This condition, caused primarily by unbalanced energy intake (overconsumption) and exacerbated by modern lifestyles such as physical inactivity and suboptimal dietary habits, is the harbinger of a variety of health disorders such as diabetes, cardiovascular disease, and certain cancers. Therefore, there is an urgent need to accurately diagnose and assess the extent of obesity in order to formulate and apply appropriate preventive measures and therapeutic interventions. However, the heterogeneous results of existing diagnostic techniques have triggered a fierce debate on the optimal approach to identifying and assessing obesity, thus complicating the search for a standard diagnostic and treatment method. This research primarily aims to use machine learning techniques to build a robust predictive model for identifying overweight or obese individuals. The proposed model, derived from a person's physical characteristics and dietary habits, was evaluated using a number of machine learning algorithms, including Multilayer Perceptron (MLP), Support Vector Machine (SVM), Fuzzy K-Nearest Neighbors (FuzzyNN), Fuzzy Unordered Rule Induction Algorithm (FURIA), Rough Sets (RS), Random Tree (RT), Random Forest (RF), Naive Bayes (NB), Logistic Regression (LR), and Decision Table (DT). Subsequently, the developed models were evaluated using a number of evaluation measures such as correlation coefficient, accuracy, kappa statistic, mean absolute error, and mean square error. The hyperparameters of the model were properly calibrated to improve accuracy. The study revealed that the random forest model (RF) had the highest accuracy of 95.78 %, closely followed by the logistic regression model (LR) with 95.22 %. Other algorithms also produced satisfactory accuracy results but could not compete with the RF and LR models. This study suggests that the pragmatic application of the model could help physicians identify overweight or obese individuals and thus accelerate the early detection, prevention, and treatment of obesity-related diseases.
Effect of granular activated carbon adsorption on mitigating microfiltration membrane fouling by algal organic matter
Authors: Zhao Ziming , He Qingsheng , Fan Jingfu , Sun Wenjun , Ray Madhumita B. 
Published: October 2023

Abstract

Algal blooms can seriously affect the operation of water treatment processes including low-pressure (micro- and ultrafiltration) and high-pressure (nanofiltration and reverse osmosis) membranes mainly due to the accumulation of algae-derived organic matter (AOM). This study investigated the effect of granular activated carbon (GAC) pretreatment on PVDF microfiltration performance for the removal of AOM. Dissolved organic matter (DOM) solution of commercial humic acid, extra- and intracellular organic matter from two species of algae, and Cyanobacteria were used for the investigation of the fouling potential of the membrane. A comparison study of different DOM removal and fouling behaviors of microfiltration (MF) after GAC adsorption as pretreatment was evaluated under variable GAC dosage and solution pH. Almost 15–20% improvement in flux and decline in irreversible fouling occurred due to the pretreatment using 1.0 g/L of GAC for an hour. The intracellular material caused higher membrane fouling than humic acid due to the hydrophilic nature of the AOM. Membrane fouling and decline in flux increased with increasing pH in the range of 5.0–8.0. The comparison results might help to provide insights into the real challenge of dealing with the treatment of algal-laden water.
Addressing non-revenue water as a global problem and its interlinkages with sustainable development goals
Authors: AbuEltayef Hatem Taha , AbuAlhin Khaldoun S. , Alastal Khalil M. 
Published: October 2023

Abstract
By 2050, over 40% of the global population could face severe water stress. The 2030 Agenda explicitly integrates water resources, supply, and sanitation, emphasizing sustainability for present and future generations. Non-revenue water (NRW) creates a barrier to sustainability through energy, water loss, and money not collected through water bills. However, NRW is well recognized by water service providers, and a comprehensive solution is lacking. Addressing NRW is vital to sustainable operations and achieving the Sustainable Development Goals (SDGs). This desk literature review investigates NRW's links with SDGs, highlighting global and local impacts, flameworking interconnections, and revealing economic, social, and environmental consequences. The study revealed that NRW not only aligns with various SDGs, particularly SDG 6 and SDG 13, but also has synergies with other goals related to energy and sustainable consumption. Reducing NRW can achieve more sustainable and resilient water systems, and contribute to the broader SDG. The cost of NRW extends beyond the financial implications for water utilities. It also encompasses the economic impacts on industries and businesses, which impacts exceeded water productivity, increased operational costs, and economic development constraints.
Impact of treatment chemicals on the morphology and molecular structure of microfibers and microplastic films in wastewater
Authors: Kaur Brar Prabhdeep , Dhir Amit , Örmeci Banu 
Published: October 2023

Abstract

This study investigated the impact of commonly used treatment chemicals on the morphology and molecular structure of microfibers (MFs) and microplastic films (MPFs) to determine whether significant changes could occur during wastewater treatment. MFs and MPFs were exposed to sodium hypochlorite (NaOCl), hydrogen peroxide (H2O2), calcium hydroxide (Ca(OH)2, pH 11), sodium hydroxide (NaOH, pH11), and hydrochloric acid (HCl, pH 3) at typical doses and exposure times used at wastewater treatment plants. Scanning electron microscopy (SEM) analysis and attenuated total reflectance-Fourier-transform infrared (ATR-FTIR) were used to examine any morphological or chemical changes after the treatment. Morphological changes were observed in the form of cracks, and increased roughness was revealed in the SEM and 3-D surface images. The results showed that MFs were more resistant to surface degradation than MPFs. Moreover, intensity peaks of ATR-FTIR revealed some partial dislodgement of the bonds in both MFs and MPFs after chemical treatment, but the overall polymer structure remained intact. The changes that occur on the surface of MFs and MPFs during chemical treatment can impact their fate, removal, and transportation behavior both at the treatment plant and after discharge to the environment.
Bamboo charcoal fiber bundles loaded MOF-derived magnetic Co/CoO porous polyhedron for efficiently catalytic degradation of tetracyclines hydrochloride
Authors: Dai Lanling , Cui Ce , Yang Mengyuan , Jiang Shan , Lan Jianwu , Guo Ronghui 
Published: October 2023

Abstract

The health of living things and the ecosystem of the planet have both been negatively impacted by antibiotic residue in the water environment. There has been a lot of interest in the catalyst made of metal-carbon compounds from MOFs as a potential solution for activating peroxymonosulfate (PMS) to produce reactive oxygen species to catalyze the degradation of residual antibiotics. In this study, zeolitic imidazolate frameworks (ZIF-67) on bamboo fiber bundles (BFB) were pyrolyzed to produce magnetic Co/CoO nanoparticles with porous polyhedrons mounted on bamboo charcoal fiber bundles (BCFB)(BCFB@PCo/CoO). Specific surface area of obtained BCFB@PCo/CoO with abundant active sites arrives at 302.41 m2/g. The catalytic degradation efficiency of Tetracycline hydrochloride (TCH), a target contaminant, could reach up to 99.94% within 15 minutes (PMS = 0.4g/L, Cat. = 0.2g/L). The effects of potential factors, including PMS dosage, interference ions, and temperature, on catalytic degradation efficiencies were investigated. Magnetic recovery and antimicrobial properties of the BCFB@PCo/CoO were also evaluated and the possible degradation pathways were explored. Catalytic mechanism explorations of BCFB@PCo/CoO/PMS system reveal MOF-derived magnetic Co/CoO nanoparticles embedded in BCFB promote the synergistic interaction of both radicals and non-radical pathways for catalytic degradation of TCH. The novel BCFB@PCo/CoO provides an alternative to deal with wastewater containing antibiotics.
Pengaruh Moderasi Risiko Bisnis pada Hubungan Struktur Kepemilikan, Struktur Aset, dan Kebijakan Dividen terhadap Kebijakan Hutang
Authors: Saputri Nio Setya , Agustina Linda 
Published: October 2023

ABSTRACTThis study aims to empirically examine the factors that debt policy in property real estate sector companies listed on the IDX in 2019-2021. The sample was selected by purposive sampling method and as many as 114 units of analysis that met the specified criteria. The results show that asset structure has a positive effect on debt policy, and business risk is able to moderate asset structure and dividend policy. Meanwhile, managerial ownership, institutional ownership, and dividend policy have no effect on debt policy, and business risk cannot moderate the effect of managerial ownership and institutional ownership. The company's management is expected to pay attention to every external funding decision in the form of debt in order to have an ideal debt ratio for the company.Keywords: Managerial Ownership, Institutional Ownership, Asset Structure, Dividend Policy, Debt Policy, Bussiness RiskABSTRAKPenelitian ini bertujuan untuk menguji secara empiris faktor yang memengaruhi kebijakan hutang pada perusahaan sektor property real estate yang terdaftar di BEI tahun 2019-2021. Sampel dipilih dengan metode purposive sampling dan sebanyak 114 unit analisis yang memenuhi kriteria yang ditetapkan. Hasil penelitian menunjukkan bahwa struktur aset berpengaruh positif terhadap kebijakan hutang, serta risiko bisnis mampu memoderasi struktur aset dan kebijakan dividen. Sementara itu, kepemilikan manajerial, kepemilikan institusional, dan kebijakan dividen tidak berpengaruh terhadap kebijakan hutang, serta risiko bisnis tidak dapat memoderasi pengaruh kepemilikan manajerial dan kepemilikan institusional. Manajemen perusahaan diharapkan dapat memperhatikan setiap keputusan pendanaan eksternal berupa hutang guna memiliki rasio hutang yang ideal bagi perusahaan.Kata Kunci: Kepemilikan Manajerial, Kepemilikan Institusional, Struktur Aset, Kebijakan Dividen, Kebijakan Hutang, Risiko Bisnis
Pengelolaan Modal Kerja, Literasi Keuangan dan Performa UMKM di Masa Pandemi Covid-19
Authors: Hamzah Ruth Samantha , Gozali Efva Octavina Donata , Efriandy Iwan , Gusmiati Dhea Maura 
Published: October 2023

ABSTRACTThe study examines the influence of WCM and financial literacy on the performance of online Micro, Small and Medium Enterprises (MSMEs). In addition, this study employs financial literacy as a moderating variable. The study was conducted using a questionnaire and obtained 117 samples of MSMEs in Palembang. The method uses cross-sectional multiple regression analysis. The results revealed that WCM has no effect on financial performance of MSMEs during Covid-19 pandemic, whilst financial literacy has a significant effect on financial performance. However, financial literacy is not able to strengthen the relationship between WCM and financial performance. The study concludes that financial literacy variables have a significant influence on financial performance. However, financial literacy is not able to moderate the relationship between WCM and financial performance. Financial literacy is a concept of information or knowledge regarding financial that forms the basis of performance capability of a company, in this case is MSMEs.Keywords: Working Capital, WCM, Financial Literacy, Financial Performance, MSMEsABSTRAKPenelitian ini bertujuan untuk mendapatkan bukti secara empiris mengenai pengaruh antara WCM dan literasi keuangan terhadap kinerja usaha mikro, kecil dan menengah (UMKM) yang sudah terdigitalisasi. Selain itu, penelitian ini menambahkan variabel literasi keuangan sebagai variabel moderasi terhadap kinerja keuangan UMKM. Penelitian dilakukan dengan menggunakan kuesioner yang melibatkan 117 sampel UMKM di Palembang. Metode penelitian ini menggunakan analisis regresi berganda cross sectional. Hasil penelitian mengungkapkan bahwa WCM tidak berpengaruh terhadap kinerja keuangan UMKM pada masa pandemi Covid-19, sedangkan literasi keuangan berpengaruh signifikan terhadap kinerja keuangan. Akan tetapi, literasi keuangan tidak mampu memperkuat hubungan WCM terhadap kinerja keuangan. Penelitian ini menyimpulkan bahwa variabel literasi keuangan memiliki pengaruh yang signifikan terhadap kinerja keuangan. Namun, literasi keuangan tidak mampu untuk memoderasi hubungan antara WCM terhadap kinerja keuangan. Literasi keuangan merupakan sebuah konsep yang berbentuk informasi ataupun suatu pengetahuan yang dapat menjadi dasar dari kemampuan suatu kinerja suatu perusahaan yang dalam hal ini adalah UMKM.Kata Kunci: Modal Kerja, WMC, Literasi Keuangan, Kinerja Keuangan, UMKM
Pengaruh GCG, Struktur Modal, dan Leverage terhadap Kinerja Keuangan Perusahaan Tambang
Authors: Islami Dian , Wulandari Anis 
Published: October 2023

ABSTRACTThe purpose of this study is to understand anythings that can affect the financial performance of oil and gas companies on the IDX for the 2015-2020 period. This study uses six independent variables, namely the Good Corporate Governance variable, which is proxied through the independent board of commissioners, managerial ownership, institutional ownership, and audit committee, as well as capital structure and leverage variables. The sample was determined through a purposive sampling technique, so nine companies matched the criteria. The quantitative method is taken by processing secondary data. The data analysis technique used is multiple linear regression analysis. This study obtained the results that independent board of commissioners, managerial ownership, institutional ownership, capital structure, and leverage have an impact on financial performance. Different results were obtained by the audit committee that had no impact on financial performance.Keywords: Independent Board of Commissioners, Managerial Ownership, Institutional Ownership, Audit Committee, Capital Structure, Leverage, Financial PerformanceABSTRAKTujuan studi ini adalah untuk memahami hal-hal yang dapat mempengaruhi kinerja keuangan pada perusahaan minyak dan gas bumi di BEI periode 2015-2020. Penelitian ini menggunakan enam variabel independen, yaitu variabel Good Corporate Governance yang diproksikan melalui dewan komisaris independen, kepemilikan manajerial, kepemilikan institusional dan komite audit, serta variabel struktur modal dan leverage. Sampel ditentukan melalui teknik purposive sampling, sehingga didapatkan sembilan perusahaan yang sesuai dengan kriteria. Metode kuantitatif diambil dengan mengolah data sekunder. Teknik analisis data yang digunakan yaitu analisis regresi linier berganda. Penelitian ini memperoleh hasil bahwa dewan komisaris independen, kepemilikan manajerial, kepemilikan institusional, struktur modal dan leverage berdampak dengan kinerja keuangan. Hasil berbeda diperoleh komite audit bahwa tidak berdampak dengan kinerja keuangan.Kata Kunci: Dewan Komisaris Independen, Kepemilikan Manajerial, Kepemilikan Institusional, Komite Audit, Struktur Modal, Leverage, Kinerja Keuangan
Predictors of Mental Health Literacy in a Sample of Health Care Major Students: Pilot Evaluation Study
Authors: Tohme Pia , Abi Fadel Nour , Yaktine Nour , Abi-Habib Rudy 
Published: October 2023

Background
The numerous mental health awareness campaigns during the COVID-19 pandemic have shifted our understanding and perception of mental health.

Objective
The purpose of this study is to evaluate predictors of mental health literacy (MHL), that is, one’s knowledge and beliefs about mental disorders. We evaluate whether digital health literacy, empathy, and mentalizing contribute to MHL.

Methods
Our sample consisted of 89 health care major students, aged between 17 and 32 years, studying at a university in Lebanon. The Mental Health Literacy Scale for Healthcare Students (MHLS-HS), the eHealth Literacy Questionnaire (eHLQ), the Basic Empathy Scale (BES), and the Reflective Functioning Questionnaire-8 (RFQ-8) were used.

Results
Multiple regression analyses revealed that the Engagement in Own Health subscale of digital health literacy constituted a predictor of MHL. While empathy and mentalizing did not directly predict MHL, they were found to predict components of MHL.

Conclusions
This is the first study to evaluate digital health literacy, empathy, and mentalizing as predictors of MHL in Lebanon, a country where mental health is still considered taboo. Moreover, this pilot study is the first to provide some support for the predictive role of some digital health literacy subscales on MHL in light of the rise of the digital era following the COVID-19 pandemic.