bluuebunny/crossref_metadata_2025_split huggingface dataset:
Hearing loss prevention at loud music events via real-time visuo-haptic feedback
Authors: Turchet Luca , Luiten Simone , Treub Tjebbe , van der Burgt Marloes , Siani Costanza , Boem Alberto 
Published: October 2023

AbstractHearing loss is becoming a global problem, partly as a consequence of exposure to loud music. People may be unaware about the harmful sound levels and consequent damages caused by loud music at venues such as discotheques or festivals. Earplugs are effective in reducing the risk of noise-induced hearing loss but have been shown to be an insufficient prevention strategy. Thus, when it is not possible to lower the volume of the sound source, a viable solution to the problem is to relocate to quieter locations from time to time. In this context, this study introduces a bracelet device with the goal of warning users when the music sound level is too loud in their specific location, via haptic, visual or visuo-haptic feedback. The bracelet embeds a microphone, a microcontroller, an LED strip and four vibration motors. We performed a user study where thirteen participants were asked to react to the three kinds of feedback during a simulated disco club event where the volume of music pieces varied to reach a loud intensity. Results showed that participants never missed the above threshold notification via all types of feedback, but visual feedback led to the slowest reaction times and was deemed the least effective. In line with the findings reported in the hearing loss prevention literature, the perceived usefulness of the proposed device was highly dependent on participants’ subjective approach to the topic of hearing risks at loud music events as well as their willingness to take action regarding its prevention. Ultimately, our study shows how technology, no matter how effective, may not be able to cope with these kinds of cultural issues concerning hearing loss prevention. Educational strategies may represent a more effective solution to the real problem of changing people’s attitudes and motivations to want to protect their hearing.
Total Glucosides of Paeony Ameliorate Myocardial Injury in Chronic Heart Failure Rats by Suppressing PARP-1
Authors: Wei Wenjuan , Li Caiyan , Zhang Baoyong , Huang Deyun , Li Zheming , Gao Jiaer 
Published: October 2023

AbstractTotal glucosides of paeony (TGP) have a potential protective effect on chronic heart failure (CHF) rats, but the mechanism remains unclear. PARP inhibition prevents the decrease in myocardial contractility. Therefore, we aim to investigate the effects and mechanisms of TGP on CHF and the role of PARP-1 in CHF. Left anterior descending ligation rats and adriamycin-treated H9C9 cells were used as CHF models, and captopril as a positive control for in vivo experiments. We found that TGP alleviated myocardial remodeling and improved cardiac morphology and function. TGP also reduced myocardial apoptosis and autophagy, decreased inflammatory factor release, and inhibited the PARP-1 and NF-κB proteins. Through cell transfection, we found that PAPR-1 knockdown inhibited NF-κB nuclear translocation. Additionally, TGP inhibited apoptosis, autophagy, and inflammation in CHF cells, while PARP-1 overexpression partially antagonized them. In conclusion, TGP has the potential to improve CHF and PARP-1 may be a potential target.
Graphical Abstract
Mechanical properties and microscopic characteristics of fly ash–slag composite backfill
Authors: Zhang Xuefeng , Zhang Xiangdong , Shuai Pang , Su Lijuan , Cai Guanjun 
Published: October 2023

AbstractThe strength of the backfill is crucial for safe and efficient mining, and the cementing material is the key to obtaining a strong backfill. In this paper, industrial waste was used as a raw material, into which basis basalt fibres of different lengths and dosages were incorporated. First, the influencing factors were determined through orthogonal test designs. The optimal ratio of solid–liquid ratio of 2 and basalt fiber content of 2% and length of 6 mm was obtained, and thereby the complete proportion of the backfill material was obtained. The compressive strength and slump of the backfill material mixed with basalt fibres were investigated, and the interfacial mechanism of the backfill material was analysed at the microscopic level using scanning electron microscopy and X-ray diffraction. The results indicated that the degrees of influence of the different factors on the mechanical properties of the backfill material decreased in the following order: Solid–liquid ratio > fibre dosage > fibre length. Furthermore, there were different degrees of interaction among them. Under the best test proportion, that is, when the Solid–liquid ratio was 2, the fibre dosage was 2%, and the fibre length was 6 mm, the slump was 210 mm, and the compressive strength was 5.03 MPa. The mechanical properties were the best at this time. Through data regression, the relationship between the fibre dosage and the average peak stress was established, and the full curve expression for the uniaxial compressive stress–strain of the BFGF specimen was obtained. According to a microscopic characterisation analysis, the slag formed C–S–H gel, which contributed to the early-stage strength of the filling material; fly ash and coal gangue contained a large amount of aluminium, which formed hydrated aluminosilicate with a framework structure, and this contributed significantly to the later-stage strength of the backfill material. The addition of basalt fibres reduces the internal defects of the backfill, allowing the internal pore structure of the backfill to be optimised and the compressive strength to be increased. The results of this study have been successfully implemented in actual projects. Additionally, they provide a reference for similar mine management projects and have considerable promotion and application value.
Application of machine learning algorithm in electronic book database management system
Authors: Zhou Jianghe , Huang Tangsen 
Published: October 2023

AbstractIntelligent algorithms have excellent performance in managing large databases and mining effective knowledge, and many researchers have introduced these algorithms into research to improve the performance of book management systems. This article introduced the application of machine learning algorithms in electronic book database management systems. A linear classifier (linear regression algorithm is one of machine learning algorithms) was used to analyze the empirical loss value. This paper studied the application of machine learning algorithm in the database management of library special collection resources, aiming to optimize the management of library special collection resources database through machine learning algorithm, and provided students with better experience of using special collection resources. This paper verified the effectiveness of the machine learning algorithm from three aspects: the retrieval time before and after the special resource database, the number of crashes in a month and the number of library staff. The average time of the five sets using the machine learning algorithm was about 150% faster than the average search time of the five sets of special resource databases. The number of crashes after using machine learning algorithm was 2, 1, 1, 2, 1, which was much lower than that of special resource database. After using the machine learning algorithm, the five groups of workers were 7, 5, 9, 6, and 4, respectively, far fewer than the five groups of special collectors. Finally, by comparing the linear regression model, Support vector machine model, and random forest model, it was found that the accuracy of the linear regression model reached 98.2%, an increase of 8.2% compared to the random forest model, the precision rate reached 96.7%, and the recall rate reached 98.2%. 97.8%, F1 value reached 97.5%.It can be seen from the experimental data that the machine learning algorithm plays a good role in the database management of the library special collection resources.
Microstructure and mechanical properties of WC–TiC–Co cemented carbides produced by spark plasma sintering (SPS) method
Authors: Aghaali Vahid , Ebadzadeh Touradj , Zahraee Seyed Mohammad , Mirkazemi Seyed Mohammad 
Published: October 2023

AbstractCemented carbide 91 wt% WC–3 wt% TiC–6 wt% Co was sintered by spark plasma sintering at different temperatures of 1200 °C, 1300 °C, and 1400 °C and the effect of sintering temperature on the microstructure and properties of this type of composites, such as total density, apparent density, hardness, and fracture surface were measured and observed using Field Emission-Scanning Electron Microscopy, Optical Microscopy, X-ray diffractometry and mechanical test instruments. The results showed that the apparent density of the samples increased with increasing sintering temperature from 1200 to 1300 °C from 13.98 to 14.23 g/cm3, respectively. But in the sample sintered at 1400 °C, the density was reduced to 14.20 g/cm3. An increase in the fluidity of the cobalt phase and capillary pressure is the cause of the increase in density at higher temperatures, the cobalt phase has evaporated and the density has decreased slightly. Also, Vickers micro-hardness results showed that the hardness of sintered samples increased with the increase of sintering temperature. For the sample sintered at 1200 °C the hardness value of 1746.41 kgf/mm2 was obtained which increased with increasing sintering temperature from 1300 to 1400 °C from 2094.33 to 2280.97 kgf/mm2, respectively. The amount of core–shell structure [including TiC-core and (W, Ti)C-shell] increased with increasing the sintering temperature process. As a result, the hardness also increased. At the optimum sintering temperature, it was found that TiC inhibited the grain growth of tungsten carbide. In addition, as expected, the grain growth of tungsten carbide increased with increasing sintering temperatures. Examination of the fracture surface of sintered samples at different temperatures also showed that brittle fracture involves fracture.
Ni(II)-doped CuWO4 photoanodes with enhanced photoelectrocatalytic activity
Authors: Nomellini Chiara , Polo Annalisa , Grigioni Ivan , Marra Gianluigi , Dozzi Maria Vittoria , Selli Elena 
Published: October 2023

AbstractCuWO4 has emerged in the last years as a ternary metal oxide material for photoanodes application in photoelectrochemical cells, thanks to its relatively narrow band gap, high stability and selectivity toward the oxygen evolution reaction, though largely limited by its poor charge separation efficiency. Aiming at overcoming this limitation, we investigate here the effects that Cu(II) ion substitution has on the photoelectrocatalytic (PEC) performance of copper tungstate. Optically transparent CuWO4 thin-film photoanodes, prepared via spin coating and containing different amounts of Ni(II) ions, were fully characterized via UV–Vis spectroscopy, XRD and SEM analyses, and their PEC performance was tested via linear sweep voltammetry, incident photon to current efficiency and internal quantum efficiency analyses. From tests performed in the presence of a hole scavenger-containing electrolyte, the charge injection and separation efficiencies of the electrodes were also calculated. Pure-phase crystalline and/or heterojunction materials were obtained with higher PEC performance compared to pure CuWO4, mainly due to a significantly enhanced charge separation efficiency in the bulk of the material.
Graphic abstract
Extended topological mode in a one-dimensional non-Hermitian acoustic crystal
Authors: Wang Xulong , Wang Wei , Ma Guancong 
Published: October 2023

AbstractIn Hermitian topological systems, topological modes (TMs) are bound to interfaces or defects of a lattice. Recent discoveries show that non-Hermitian effects can reshape the wavefunctions of the TMs and even turn them into extended modes occupying the entire bulk lattice. In this letter, we experimentally demonstrate such an extended TM (ETM) in a one-dimensional (1D) non-Hermitian acoustic topological crystal. The acoustic crystal is formed by a series of coupled acoustic resonant cavities, and the non-Hermiticity is introduced as a non-reciprocal coupling coefficient using active electroacoustic controllers (AECs). Our work highlights the potential universality of ETMs in different physical systems and resolves the technical challenges in the further study of ETMs in acoustic waves.
Recent advances in cancer-on-a-chip tissue models to dissect the tumour microenvironment
Authors: Seaman Kimberly , Sun Yu , You Lidan 
Published: October 2023

AbstractThree-dimensional cancer-on-a-chip tissue models aim to replicate the key hallmarks of the tumour microenvironment and allow for the study of dynamic interactions that occur during tumour progression. Recently, complex cancer-on-a-chip models incorporating multiple cell types and biomimetic extracellular matrices have been developed. These models have generated new research directions in engineering and medicine by allowing for the real-time observation of cancer-host cell interactions in a physiologically relevant microenvironment. However, these cancer-on-a-chip models have yet to overcome limitations including the complexity of device manufacturing, the selection of optimal materials for preclinical drug screening studies, long-term microfluidic cell culture as well as associated challenges, and the technical robustness or difficulty in the use of these microfluidic platforms. In this review, an overview of the tumour microenvironment, its unique characteristics, and the recent advances of cancer-on-a-chip models that recapitulate native features of the tumour microenvironment are presented. The current challenges that cancer-on-a-chip models face and the future directions of research that are expected to be seen are also discussed.
Graphical Abstract
Broad functional landscape of geminivirus-encoded C4/AC4 protein
Authors: Mei Yuzhen , Wang Yaqin , Zhou Xueping 
Published: October 2023

AbstractGeminiviruses induce severe developmental abnormalities in crops and cause severe economic losses worldwide. Owing to the limited coding capacity of the viral genome, geminiviruses produce a limited number of multifunctional effectors to adapt to the host cellular environment. Among these effectors, the geminivirus-encoded C4/AC4 protein is a powerful viral effector with unexpected versatility. Here, we summarize the current knowledge on this remarkable protein and discuss future work on the C4/AC4 protein to provide new insights into plant-geminivirus interactions and integrated control of diseases induced by them.
The effectiveness of COVID-19 vaccine in the prevention of post-COVID conditions: a systematic literature review and meta-analysis of the latest research
Authors: Marra Alexandre R. , Kobayashi Takaaki , Callado Gustavo Yano , Pardo Isabele , Gutfreund Maria Celidonio , Hsieh Mariana Kim , Lin Vivian , Alsuhaibani Mohammed , Hasegawa Shinya , Tholany Joseph , Perencevich Eli N. , Salinas Jorge L. , Edmond Michael B. , Rizzo Luiz Vicente 
Published: October 2023

Abstract

Objective:
We performed a systematic literature review and meta-analysis on the effectiveness of coronavirus disease 2019 (COVID-19) vaccination against post-COVID conditions (long COVID) among fully vaccinated individuals.

Design:
Systematic literature review/meta-analysis.

Methods:
We searched PubMed, Cumulative Index to Nursing and Allied Health, EMBASE, Cochrane Central Register of Controlled Trials, Scopus, and Web of Science from December 1, 2019, to June 2, 2023, for studies evaluating the COVID-19 vaccine effectiveness (VE) against post-COVID conditions among fully vaccinated individuals who received two doses of COVID-19 vaccine. A post-COVID condition was defined as any symptom that was present four or more weeks after COVID-19 infection. We calculated the pooled diagnostic odds ratio (DOR) (95% confidence interval) for post-COVID conditions between fully vaccinated and unvaccinated individuals. Vaccine effectiveness was estimated as 100% x (1-DOR).

Results:
Thirty-two studies with 775,931 individuals evaluated the effect of vaccination on post-COVID conditions, of which, twenty-four studies were included in the meta-analysis. The pooled DOR for post-COVID conditions among fully vaccinated individuals was 0.680 (95% CI: 0.523–0.885) with an estimated VE of 32.0% (11.5%–47.7%). Vaccine effectiveness was 36.9% (23.1%–48.2%) among those who received two doses of COVID-19 vaccine before COVID-19 infection and 68.7% (64.7%–72.2%) among those who received three doses before COVID-19 infection. The stratified analysis demonstrated no protection against post-COVID conditions among those who received COVID-19 vaccination after COVID-19 infection.

Conclusions:
Receiving a complete COVID-19 vaccination prior to contracting the virus resulted in a significant reduction in post-COVID conditions throughout the study period, including during the Omicron era. Vaccine effectiveness demonstrated an increase when supplementary doses were administered.
Asha Bhandary's Freedom to Care — A Kantian Care Engagement
Authors: Varden Helga 
Published: October 2023

AbstractThis review locates Asha Bhandary's Freedom to Care in the history of philosophy, notes some of the theory's distinctive features that clearly advance the care theory tradition, and raises some puzzles and questions regarding specific elements of the theory. My remarks focus mostly on Part I of the book and on the following four topics: (1) Bhandary's Rawlsian roots, (2) Bhandary's engagement with Eva Feder Kittay, (3) Bhandary's choice of J. S. Mill and John Rawls as her main historical interlocutors, and finally, (4) Bhandary's methodological choice of ‘men/fathers,’ ‘women/mothers,’ and ‘children/girls/boys’ as the main focus of much of her analysis.
Introduction to Symposium on Asha Bhandary's Freedom to Care
Authors: McKittrick-Sweitzer Lavender 
Published: October 2023

AbstractIn this introduction, I offer a broad overview of Asha Bhandary's Freedom to Care: Liberalism, Dependency Care, and Culture so that readers can better situate the suggestions of this symposium's contributors: Clark Wolf, Elizabeth Edenberg, and Helga Varden. Bhandary develops and defends the theory of liberal dependency care in response to the failure of past liberal theorizing to appreciate that dependency care — which is essential to our survival — is a matter of justice. By concluding with a Hamptonian framing, I hope to further generate discussion of this novel work that broadens the influence of contemporary feminist liberal theorizing.
Liberal Dependency Care Versus Subject-Centered Liberal Justice
Authors: Wolf Clark 
Published: October 2023

AbstractJohn Rawls and Asha Bhandary use David Hume's conditions of justice to frame the original position choice from which principles of justice are selected. To use Hume's conditions in this way excludes from representation those who are not full cooperators, including people who need lifelong dependency care. This implies that their claim to dependent care is not a fundamental claim of justice, but must have significantly lower priority. This article argues that an appropriate theory of liberal dependency care will abandon this Humean framing assumption, and will treat the claim to dependency care as a fundamental requirement of justice.
Phonological emergence and social reorganization: Developing a nasal /æ/ system in Lansing, Michigan
Authors: Nesbitt Monica 
Published: October 2023

AbstractPhonological rule innovation is thought to come about via reanalysis of some phonetic variation (e.g., Bermúdez-Otero, 2007; Hyman, 1975; Ohala, 1981; Pierrehumbert, 2001). Yet, empirical evidence suggests instead that the role of phonetic variation during phonological rule innovation is minor (Fruehwald, 2013, 2016). This paper adds to this ongoing debate an empirical analysis of an emergent allophonic contrast—an “/æ/ nasal system”—in White Michigan English. Analyses of speaker-level acoustic data from a sociolinguistic corpus (n = 36) and a subphonemic judgment task (n = 107) suggest that Lansing exhibits gradual phonological rule emergence. Social conditioning appears to act as the catalyst of phonological rule formation and its spread. The mechanism of actuation was thus “the chance alignment of social and phonetic variability” (Baker, Archangeli, & Mielke, 2011), suggesting that social conditioning on phonetic variability must play a major role in phonological emergence.
Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: implications for foetal programming
Authors: Pham Cindy , Thomson Sarah , Chin Sung-Tong , Vuillermin Peter , O’Hely Martin , Burgner David , Tanner Samuel , Saffery Richard , Mansell Toby , Bong Sze , Holmes Elaine , Sly Peter D. , Gray Nicola , Ponsonby Anne-Louise ,   Barwon Infant Study Investigator Group, Carlin John , Tang Mimi , Collier Fiona , Loughman Amy , Ranganathan Sarath , Gray Lawrence 
Published: October 2023

AbstractChildhood mental disorders, including emotional and behavioural problems (EBP) are increasingly prevalent. Higher maternal oxidative stress (OS) during pregnancy (matOSpreg) is linked to offspring mental disorders. Environmental factors contribute to matOSpreg. However, the role of matOSpreg in childhood EBP is unclear. We investigated the associations between (i) matOSpreg and offspring EBP; (ii) social and prenatal environmental factors and matOSpreg; and (iii) social and prenatal factors and childhood EBP and evaluated whether matOSpreg mediated these associations. Maternal urinary OS biomarkers, 8-hydroxyguanosine (8-OHGua; an oxidative RNA damage marker) and 8-hydroxy-2′-deoxyguanosine (8-OHdG; an oxidative DNA damage marker), at 36 weeks of pregnancy were quantified by liquid chromatography-mass spectrometry in a population-derived birth cohort, Barwon Infant Study (n = 1074 mother-infant pairs). Social and prenatal environmental factors were collected by mother-reported questionnaires. Offspring total EBP was measured by Child Behavior Checklist Total Problems T-scores at age two (n = 675) and Strengths and Difficulties Questionnaire Total Difficulties score at age four (n = 791). Prospective associations were examined by multivariable regression analyses adjusted for covariates. Mediation effects were evaluated using counterfactual-based mediation analysis. Higher maternal urinary 8-OHGua at 36 weeks (mat8-OHGua36w) was associated with greater offspring total EBP at age four (β = 0.38, 95% CI (0.07, 0.69), P = 0.02) and age two (β = 0.62, 95% CI (−0.06, 1.30), P = 0.07). Weaker evidence of association was detected for 8-OHdG. Five early-life factors were associated with both mat8-OHGua36w and childhood EBP (P-range < 0.001–0.05), including lower maternal education, socioeconomic disadvantage and prenatal tobacco smoking. These risk factor-childhood EBP associations were partly mediated by higher mat8-OHGua36w (P-range = 0.01–0.05). Higher matOSpreg, particularly oxidant RNA damage, is associated with later offspring EBP. Effects of some social and prenatal lifestyle factors on childhood EBP were partly mediated by matOSpreg. Future studies are warranted to further elucidate the role of early-life oxidant damage in childhood EBP.