bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estimating the pressure force around swimming plankton using micro particle image velocimetry
Authors: Ergin Fahrettin Gökhan , Günaydınoğlu Erkan , Kurtuluş Dilek Funda , Wadhwa Navish 
Published: November 2023

Abstract
Obtaining pressure force for freely swimming microorganisms is a challenging yet important problem. Here, we report the swimming kinematics and dynamics of the zooplankton Acartia tonsa nauplius investigated using Micro Particle Image Velocimetry (µPIV). Using rigid object tracking, we obtain sub-pixel accurate localization of freely swimming A. tonsa, revealing its highly periodic locomotion. We exploit this periodicity to obtain phase-locked averaged kinematics for position, speed, and acceleration. The swimming speed profile of A. tonsa has a distinct double peak, due to its two power strokes. Next, we investigate the flow field around swimming A. tonsa using µPIV. We dynamically mask A. tonsa in µPIV images using an object-fixed coordinate transformation, leveraging the sub-pixel accurate localization. Our analysis shows of a pair of attached vortices during the two power strokes, which are pushed away during the recovery stroke. Finally, using a semi-implicit pressure velocity algorithm, we calculate the pressure force from the time-dependent flow fields. These calculations indicate a low-pressure region ahead of the A. tonsa during the peak of the power strokes. The vertical pressure force correlates well with the vertical swimming speed.
Exploring the impact of combining women’s empowerment through village savings and loans associations with men’s sensitization on gender equity on socio-economic, maternal, and children’s health outcomes
Authors: Bapolisi Wyvine , Makelele Jean , Kono-Tange Lenneke , Bisimwa Ghislain , Merten Sonja 
Published: November 2023

Abstract

Background
The Democratic Republic of the Congo is among the poorest countries in the world with a low gender development index. To help households improve their economic levels and address gender-based violence, the Mawe Tatu programme was created to combine women’s empowerment through village savings and loans associations (VSLA) with engaging men in changing their attitudes and adopting positive masculinities.

Methods
This study explores the impact of women’s empowerment through VSLA while their husbands participate in a men’s reflection group pursuing a gender equity curriculum. Data were collected over three years through focus group discussions and in-depth interviews with both men and women. Data were analysed using an inductive approach, building themes based on respondents’ narratives.

Results
Household welfare was described as ‘improved’ when both partners participated in the intervention. More cash was available in the household, cohesion within the couple increased, and men were more likely to involve their wives in decision-making processes. Men were also more involved in childcare and more concerned about their partner’s health, especially during pregnancy.

Conclusion
Combining women's economic empowerment through VSLA while raising awareness of gender equity among their husbands is a promising approach. However, it is necessary to develop positive femininities in parallel to positive masculinities, as women to avoid being judged, may fear changes preserving empirical gender norms. Creating more ‘friendly’ and inclusive spaces in health centers will make it easier for men to accompany their wives for maternal health services.
Shared and malignancy-specific functional plasticity of dynamic brain properties for patients with left frontal glioma
Authors: Cai Siqi , Liang Yuchao , Wang Yinyan , Fan Zhen , Qi Zengxin , Liu Yufei , Chen Fanfan , Jiang Chunxiang , Shi Zhifeng , Wang Lei , Zhang Lijuan 
Published: November 2023

Abstract
The time-varying brain activity may parallel the disease progression of cerebral glioma. Assessment of brain dynamics would better characterize the pathological profile of glioma and the relevant functional remodeling. This study aims to investigate the dynamic properties of functional networks based on sliding-window approach for patients with left frontal glioma. The generalized functional plasticity due to glioma was characterized by reduced dynamic amplitude of low-frequency fluctuation of somatosensory networks, reduced dynamic functional connectivity between homotopic regions mainly involving dorsal attention network and subcortical nuclei, and enhanced subcortical dynamic functional connectivity. Malignancy-specific functional remodeling featured a chaotic modification of dynamic amplitude of low-frequency fluctuation and dynamic functional connectivity for low-grade gliomas, and attenuated dynamic functional connectivity of the intrahemispheric cortico-subcortical connections and reduced dynamic amplitude of low-frequency fluctuation of the bilateral caudate for high-grade gliomas. Network dynamic activity was clustered into four distinct configuration states. The occurrence and dwell time of the weakly connected state were reduced in patients’ brains. Support vector machine model combined with predictive dynamic features achieved an averaged accuracy of 87.9% in distinguishing low- and high-grade gliomas. In conclusion, dynamic network properties are highly predictive of the malignant grade of gliomas, thus could serve as new biomarkers for disease characterization.
Posterior parietal cortex is causally involved in reward valuation but not in probability weighting during risky choice
Authors: Panidi Ksenia , Vorobiova Alicia N , Feurra Matteo , Klucharev Vasily 
Published: November 2023

Abstract
This study provides evidence that the posterior parietal cortex is causally involved in risky decision making via the processing of reward values but not reward probabilities. In the within-group experimental design, participants performed a binary lottery choice task following transcranial magnetic stimulation of the right posterior parietal cortex, left posterior parietal cortex, and a right posterior parietal cortex sham (placebo) stimulation. The continuous theta-burst stimulation protocol supposedly downregulating the cortical excitability was used. Both, mean–variance and the prospect theory approach to risky choice showed that the posterior parietal cortex stimulation shifted participants toward greater risk aversion compared with sham. On the behavioral level, after the posterior parietal cortex stimulation, the likelihood of choosing a safer option became more sensitive to the difference in standard deviations between lotteries, compared with sham, indicating greater risk avoidance within the mean–variance framework. We also estimated the shift in prospect theory parameters of risk preferences after posterior parietal cortex stimulation. The hierarchical Bayesian approach showed moderate evidence for a credible change in risk aversion parameter toward lower marginal reward value (and, hence, lower risk tolerance), while no credible change in probability weighting was observed. In addition, we observed anecdotal evidence for a credible increase in the consistency of responses after the left posterior parietal cortex stimulation compared with sham.
Dissociable contributions of the hippocampus and orbitofrontal cortex to representing task space in a social context
Authors: Liao Jiajun , Li Jinhui , Qiu Yidan , Wu Xiaoyan , Liu Bingyi , Zhang Lu , Zhang Yuting , Peng Xiaoqi , Huang Ruiwang 
Published: November 2023

Abstract
The hippocampus (HC) and the orbitofrontal cortex (OFC) jointly encode a map-like representation of a task space to guide behavior. It remains unclear how the OFC and HC interact in encoding this map-like representation, though previous studies indicated that both regions have different functions. We acquired the functional magnetic resonance imaging data under a social navigation task in which participants interacted with characters in a two-dimensional “social space.” We calculate the social relationships between the participants and characters and used a drift-diffusion model to capture the inner process of social interaction. Then we used multivoxel pattern analysis to explore the brain-behavior relationship. We found that (i) both the HC and the OFC showed higher activations during the selective trial than the narrative trial; (ii) the neural pattern of the right HC was associated with evidence accumulation during social interaction, and the pattern of the right lateral OFC was associated with the social relationship; (iii) the neural pattern of the HC can decode the participants choices, while the neural pattern of the OFC can decode the task information about trials. The study provided evidence for distinct roles of the HC and the OFC in encoding different information when representing social space.
Novel inductively coupled ear-bars (ICEs) to enhance restored fMRI signal from susceptibility compensation in rats
Authors: Chen Yi , Fernandez Zachary , Scheel Norman , Gifani Mahsa , Zhu David C , Counts Scott E , Dorrance Anne M , Razansky Daniel , Yu Xin , Qian Wei , Qian Chunqi 
Published: November 2023

Abstract
Functional magnetic resonance imaging faces inherent challenges when applied to deep-brain areas in rodents, e.g. entorhinal cortex, due to the signal loss near the ear cavities induced by susceptibility artifacts and reduced sensitivity induced by the long distance from the surface array coil. Given the pivotal roles of deep brain regions in various diseases, optimized imaging techniques are needed. To mitigate susceptibility-induced signal losses, we introduced baby cream into the middle ear. To enhance the detection sensitivity of deep brain regions, we implemented inductively coupled ear-bars, resulting in approximately a 2-fold increase in sensitivity in entorhinal cortex. Notably, the inductively coupled ear-bar can be seamlessly integrated as an add-on device, without necessitating modifications to the scanner interface. To underscore the versatility of inductively coupled ear-bars, we conducted echo-planner imaging-based task functional magnetic resonance imaging in rats modeling Alzheimer’s disease. As a proof of concept, we also demonstrated resting-state-functional magnetic resonance imaging connectivity maps originating from the left entorhinal cortex—a central hub for memory and navigation networks-to amygdala hippocampal area, Insular Cortex, Prelimbic Systems, Cingulate Cortex, Secondary Visual Cortex, and Motor Cortex. This work demonstrates an optimized procedure for acquiring large-scale networks emanating from a previously challenging seed region by conventional magnetic resonance imaging detectors, thereby facilitating improved observation of functional magnetic resonance imaging outcomes.
Temporary employment and wage inequality over the life course
Authors: Janietz Christoph , Bol Thijs , Lancee Bram 
Published: November 2023

Abstract
Wage inequality between workers with different levels of educational attainment has been shown to increase over the life course. In this study, we investigate to what extent this growth is explained by temporary employment. Using linked employer-employee register data from the Netherlands, we follow the labour market careers of workers born in 1979. We decompose the impact of temporary employment on the change in the wage gap over the life course into two distinct components: (i) changes in group-specific temporary employment rates (risk) and (ii) changes in group-specific effects of temporary employment on wages (vulnerability). In line with previous research, we find a marked growth of the educational wage gap over the life course in the Netherlands. While group differences in temporary employment risk changed throughout the observation period to the detriment of less-educated workers, group differences in vulnerability to temporary employment diverged specifically during the early life course. Overall, temporary employment explains around 9 per cent of the change in the wage gap between workers with different levels of educational attainment by the age of 38 relative to age 28.
External influences over Senegalese health financing policy: delaying universal health coverage?
Authors: Ridde Valéry , Caffin Jean-Hugues , Hane Fatoumata 
Published: November 2023

Abstract
Senegal has long sought solutions to achieve universal health coverage (UHC). However, in a context dependent on international aid, the country faces multiple external pressures to choose policy instruments. In this commentary, we propose an analysis of this influence. The empirical material comes from our involvement in analysing health reforms for 20 years and from many interviews and observations. While studies have shown that community-based health insurance (CBHI) was not an appropriate solution for UHC, some international actors have influenced their continued application. Another global partner proposed an alternative (professional and departmental CBHI), which was counteracted and delayed. These issues of powers and influences of international and national consultants, established in a neo-liberal approach to health, have lost at least a decade from UHC in Senegal. The alternative now appears to be acquired and is scaling up at the country level, witnessing a change in the current policy paradigm.
Protecting children from unhealthy food marketing: a comparative policy analysis in Australia, Fiji and Thailand
Authors: Thow Anne Marie , Phulkerd Sirinya , Ngqangashe Yandisa , Ravuvu Amerita , Zaruba Liza , Huckel Schneider Carmen , Collin Jeff , Schram Ashley , Friel Sharon 
Published: November 2023

Abstract
Restrictions on marketing of unhealthy foods and beverages to children is a globally recommended policy measure to improve diets and health. The aim of the analysis was to identify opportunities to enable policy learning and shift beliefs of relevant actors, to engender policy progress on restrictions on marketing of unhealthy foods to children. We drew on the Advocacy Coalition Framework to thematically analyse data from qualitative policy interviews conducted Australia (n = 24), Fiji (n = 10) and Thailand (n = 20). In all three countries two clear and opposing advocacy coalitions were evident within the policy subsystem related to regulation of unhealthy food marketing, which we termed the ‘strengthen regulation’ and ‘minimal/self regulation’ coalitions. Contributors to policy stasis on this issue were identified as tensions between public health and economic objectives of government, and limited formal and informal spaces for productive dialogue. The analysis also identified opportunities for policy learning that could enable policy progress on restrictions on marketing of unhealthy foods to children as: taking an incremental approach to policy change, defining permitted (rather than restricted) foods, investing in new public health expertise related to emerging marketing approaches and scaling up of monitoring of impacts. The insights from this study are likely to be relevant to many countries seeking to strengthen regulation of marketing to children, in response to recent global recommendations.
What should we talk about? Contributions from Freirean Thematic Investigation in health education with adolescents
Authors: Gontijo Daniela Tavares , Calheiros Maria Natália Santos , Jucá Adriana Lobo , Monteiro Rosana Juliet Silva 
Published: November 2023

Abstract
Adolescence is an essential stage of life for developing actions related to health promotion, especially in health education (HE). Public policies advocate for the expansion of participative technologies in this field, as well as different theoretical and methodological perspectives subsidize these. Among these, Paulo Freire's reference guide is practiced in Brazil and around the world. From the Freirean perspective, Thematic Investigation (TI) defines the content of the educational practice. This paper describes a methodological proposal of the Freirean Thematic Investigation for developing health educational practices and promoting health among adolescents. Initially, we describe the conception of the Freirean rationale that sets the grounds for the proposed method: human being, dialogical education and reality and their connections with HE with adolescents in a critical perspective. The methodological proposal is systematized into five stages: (i) Approaching adolescents and the field of educational practices; (ii) Reading reality; (iii) Seminars for analyzing reality reading and preparing the codifications; (iv) Critical analysis of reality; and (v) Planning educational practices. The TI confronts the adult-centric perspectives that characterize adolescent health care. Moreover, as a praxis, TI is a process of reflection and action with adolescents, allowing for not only the discovery of the themes that build educational practices but also for solutions (untested feasibility) for the individual and collective problems experienced by adolescents concerning their health.
Automatic Segmentation and Radiomics for Identification and Activity Assessment of CTE Lesions in Crohn’s Disease
Authors: Gao Yankun , Zhang Bo , Zhao Dehan , Li Shuai , Rong Chang , Sun Mingzhai , Wu Xingwang 
Published: November 2023

Abstract

Background
The purpose of this article is to develop a deep learning automatic segmentation model for the segmentation of Crohn’s disease (CD) lesions in computed tomography enterography (CTE) images. Additionally, the radiomics features extracted from the segmented CD lesions will be analyzed and multiple machine learning classifiers will be built to distinguish CD activity.

Methods
This was a retrospective study with 2 sets of CTE image data. Segmentation datasets were used to establish nnU-Net neural network’s automatic segmentation model. The classification dataset was processed using the automatic segmentation model to obtain segmentation results and extract radiomics features. The most optimal features were then selected to build 5 machine learning classifiers to distinguish CD activity. The performance of the automatic segmentation model was evaluated using the Dice similarity coefficient, while the performance of the machine learning classifier was evaluated using the area under the curve, sensitivity, specificity, and accuracy.

Results
The segmentation dataset had 84 CTE examinations of CD patients (mean age 31 ± 13 years, 60 males), and the classification dataset had 193 (mean age 31 ± 12 years, 136 males). The deep learning segmentation model achieved a Dice similarity coefficient of 0.824 on the testing set. The logistic regression model showed the best performance among the 5 classifiers in the testing set, with an area under the curve, sensitivity, specificity, and accuracy of 0.862, 0.697, 0.840, and 0.759, respectively.

Conclusion
The automated segmentation model accurately segments CD lesions, and machine learning classifier distinguishes CD activity well. This method can assist radiologists in promptly and precisely evaluating CD activity.
A comparison of the incidence of ≥ grade 2 radiation pneumonitis between intensity-modulated radiotherapy and three-dimensional conformal radiotherapy in patients with unresectable non-small cell lung cancer treated with durvalumab after concurrent chemoradiotherapy
Authors: Masuo Masahiro , Shinohara Eiko , Kitano Masataka , Maruta Ryusuke , Chonabayashi Satoshi , Endo Shun , Matumoto Suhei , Nishiyama Naoki , Machitori Yumiko , Kobayashi Masayoshi 
Published: November 2023

Abstract

Background
Intensity-modulated radiation therapy (IMRT) has been increasingly used as a new radiation modality for unresectable non-small cell lung cancer (NSCLC). The risk factors for radiation pneumonitis (RP) during consolidation durvalumab following concurrent chemoradiotherapy (CCRT) using IMRT have not been thoroughly investigated.

Methods
This retrospective study analyzed medical record data from consecutive patients diagnosed with NSCLC who underwent CCRT and consolidation durvalumab at our institution between April 2018 and September 2022. Since we adopted IMRT for the treatment of NSCLC in April 2020, these patients were categorized into two groups: those treated with IMRT after April 2020 and those treated with three-dimensional conformal radiotherapy (3D-CRT) before April 2020.

Results
A total of 31 patients underwent IMRT (the IMRT group), while 25 patients underwent 3D-CRT (the 3D-CRT group). In both groups, the total dose was 60 Gy in 30 fractions. The cumulative incidence of ≥ grade 2 RP at 12 months was significantly lower in the IMRT group than in the 3D-CRT group (27.0% vs. 64.0%, hazard ratio [HR]: 0.338, 95% confidence interval [CI]: 0.144–0.793, p = 0.013). In the multivariable analysis, V20 (≥ 25.6%, HR: 2.706, 95% CI: 1.168–6.269, p = 0.020) and radiotherapy technique (IMRT, HR: 0.414, 95% CI: 0.172–0.994, p = 0.048) were identified as significant risk factors for ≥ grade 2 RP.

Conclusions
IMRT is associated with a lower rate of ≥ grade 2 RP in patients with NSCLC who received CCRT followed by durvalumab.
Negative Events and Compositional Semantics
Authors: Bernard Timothée , Champollion Lucas 
Published: November 2023

AbstractMotivated by intuitive parallels between event descriptions with and without linguistic negation, we develop a formalization of negative events. We propose that verbal negation denotes a function ${\textit{Neg}}$, which sends any set of events $P$ to a set ${\textit{Neg}}(P)$ constrained by a principle ensuring that any event in ${\textit{Neg}}(P)$ occurs if and only if no event in $P$ does. This allows us to construe the events in ${\textit{Neg}}(P)$ as negative, “anti-$P$”, events. Our formalization of ${\textit{Neg}}$ is conceptually related to truthmaker semantics but only requires standard logical tools, and it is compatible with standard versions of event semantics. We develop an explicit syntax-semantics interface and compositional analyses of the interaction of negation with disjunction, conjunction, quantifiers, and nonfinite perception reports.
Temperature-dependent action of pepper mildew resistance locus O 1 in inducing pathogen immunity and thermotolerance
Authors: Huang Xueying , Yang Sheng , Zhang Yapeng , Shi Yuanyuan , Shen Lei , Zhang Qixiong , Qiu Ailian , Guan Deyi , He Shuilin 
Published: November 2023

Abstract
Plant diseases tend to be more serious under conditions of high-temperature/high-humidity (HTHH) than under moderate conditions, and hence disease resistance under HTHH is an important determinant for plant survival. However, how plants cope with diseases under HTHH remains poorly understood. In this study, we used the pathosystem consisting of pepper (Capsicum annuum) and Ralstonia solanacearum (bacterial wilt) as a model to examine the functions of the protein mildew resistance locus O 1 (CaMLO1) and U-box domain-containing protein 21 (CaPUB21) under conditions of 80% humidity and either 28 °C or 37 °C. Expression profiling, loss- and gain-of-function assays involving virus-induced gene-silencing and overexpression in pepper plants, and protein–protein interaction assays were conducted, and the results showed that CaMLO1 acted negatively in pepper immunity against R. solanacearum at 28 °C but positively at 37 °C. In contrast, CaPUB21 acted positively in immunity at 28 °C but negatively at 37 °C. Importantly, CaPUB21 interacted with CaMLO1 under all of the tested conditions, but only the interaction in response to R. solanacearum at 37 °C or to exposure to 37 °C alone led to CaMLO1 degradation, thereby turning off defence responses against R. solanacearum at 37 °C and under high-temperature stress to conserve resources. Thus, we show that CaMLO1 and CaPUB21 interact with each other and function distinctly in pepper immunity against R. solanacearum in an environment-dependent manner.