bluuebunny/crossref_metadata_2025_split huggingface dataset:
Morphology of the wings and attachment apparatus in the evolution of the family Hippoboscidae (Diptera)
Authors: YATSUK Aleksandra A. , TRISELEVA Tatiana A. , NARCHUK Emilia P. , MATYUKHIN Aleksandr V. , SAFONKIN Andrey F. 
Published: December 2023

AbstractUsing a complex analysis of the molecular genetics, morphological, and ecological characteristics of Hippoboscidae flies, the phylogenetic structure and trends in the evolution of morphological characters that contribute to the ectoparasitic lifestyle of hippoboscid flies of the north of Eurasia were studied for the first time. The research was carried out on 26 Palearctic species from 10 genera. The analysis of molecular phylogeny revealed the levels of clustering of the family with the species predominantly parasitizing mammals or birds, the time of cluster formation, and the divergence of species in the Palearctic conditions. An independent adaptation to birds occurred in the genera Icosta, Pseudolynchia, Ornithoica, and others. Bird parasites are characterized by bifid tarsal claws, long hooks on pulvilli, and long empodium setae (except genus Ornithoica). Mammalian parasites are characterized by simple tarsal claws, short lobes of hooks on pulvilli, and zones on empodium with short setae. Specialization in empodium and pulvillus morphotypes and wing reduction are higher diverged in mammalian parasites than in bird parasites. The decrease of flight ability and wing reduction independently arose in different subfamilies of Hippoboscidae flies. Our results assume that the tribe Ornithomyini is a paraphyletic group, since, according to the complex of morphological features, the genus Ornithoica can be considered a separate lineage of evolution.
Lipocalin 2—A bone‐derived anorexigenic and β‐cell promoting signal: From mice to humans
Authors: Yang Yuying , Liu Jianmin , Kousteni Stavroula 
Published: December 2023

AbstractThe skeleton is traditionally known for its structural support, organ protection, movement, and maintenance of mineral homeostasis. Over the last 10 years, bone has emerged as an endocrine organ with diverse physiological functions. The two key molecules in this context are fibroblast growth factor 23 (FGF23), secreted by osteocytes, and osteocalcin, a hormone produced by osteoblasts. FGF23 affects mineral homeostasis through its actions on the kidneys, and osteocalcin has beneficial effects in improving glucose homeostasis, muscle function, brain development, cognition, and male fertility. In addition, another osteoblast‐derived hormone, lipocalin 2 (LCN2) has emerged into the researchers' field of vision. In this review, we mainly focus on LCN2's role in appetite regulation and glucose metabolism and also briefly introduce its effects in other pathophysiological conditions, such as nonalcoholic fatty liver disease, sarcopenic obesity, and cancer‐induced cachexia.image
Formal versus informal supervisor socio‐emotional support behaviours and employee trust: The role of cultural power distance
Authors: Cho Jaee , Wasti S. Arzu , Savani Krishna , Tan Hwee Hoon , Morris Michael W. 
Published: December 2023

AbstractThis research investigates how formal versus informal supervisor support behaviours shape employees' affect‐ and cognition‐based trust across cultures of varying power distance. Using data from in‐depth interviews, Study 1 found that trust‐enhancing supervisor behaviours were more formal, status conscious and imposing in India (a high power distance culture) than in the Netherlands (a low power distance culture); unlike in India, supervisors acted more like friends or equals with their subordinates in the Netherlands. Using vignettes, Study 2 found that, compared to informal support behaviours, formal support behaviours increased both affect‐ and cognition‐based trust among Indian participants, but among US participants, formal support behaviours only increased cognition‐based trust. Study 3 conceptually replicated those findings by manipulating power distance in an organization. Together, the findings from these three studies suggest that supervisors' formal socio‐emotional support behaviours are particularly effective in increasing affect‐based trust in societal and organizational cultures that are high power distance.
Placental weight percentile curves in a Danish population
Authors: Victor Simon Foged , Jeppegaard Maria , Rasmussen Steen Christian , Larsen Marie Høygaard , Krebs Lone 
Published: December 2023

AbstractIntroductionThe role of the placenta is to transport oxygen and nutrients to the fetus, and a well‐functioning placenta is vital to fetal health. Our aim was to develop placental weight percentile curves adjusted by gestational age, and stratified by major maternal comorbidities.Material and methodsThe study was a population study in a Danish cohort. Data was drawn from The Medical Birth Register and the National Patient Register. We included singleton births with a gestational age of 22 + 0 to 42 + 6 weeks. We excluded multiple pregnancies, stillbirths and retained placentas. A total of 611 418 placentas were included. Percentile line graphs were created in groups of all placentas, hypertensive disorders and diabetic disorders.ResultsTables and figures are presented for placental weight percentile curves according to gestational age for all placentas, hypertensive disorders and diabetic disorders, respectively. Placental weight was generally higher in the diabetic placentas, and lower in the hypertensive placentas.ConclusionsThese percentile curves may serve as a reference for other populations, and may be useful for other studies investigating the role of the placenta in relation to pregnancy outcomes, and health in later life.
COVID‐19 and the adequacy of antenatal care among Indigenous women: A retrospective crossover analysis
Authors: Aguilar‐Rodríguez María Alejandra , Castro‐Porras Lilia V. 
Published: December 2023

AbstractBackgroundOften marginalized and disadvantaged by systems of oppression, Indigenous populations commonly face significant barriers to accessing adequate antenatal care (ANC). The COVID‐19 pandemic had an unprecedented impact on healthcare systems worldwide, including on the provision of antenatal care; this was especially so for Indigenous communities in many regions. As such, our study aimed to estimate the association between the COVID‐19 pandemic and adequate ANC received by Indigenous women in Chiapas, Mexico.MethodsWe conducted a retrospective crossover analysis with data collected between June and December 2021 from Indigenous women who attended at least one ANC appointment at one of two health centers in San Cristóbal de las Casas, Chiapas. We used a multinomial logistic regression model considering the time frame (before and during the pandemic) as the primary independent variable. Adequate antenatal care comprised four dimensions: attendance by qualified personnel, timely first visit, sufficient frequency of visits, and adequacy of the content provided during the visits.ResultsDuring the COVID‐19 pandemic, there was a significant drop in ANC adequacy, with 12.7% (95% CI: 8.3, 18.9) of Indigenous women receiving ANC, compared with the pre‐pandemic rate of 52.5% (95% CI: 44.7, 60.3), among the 158 participants. The pandemic resulted in a reduction of 75.8% in the adequacy of ANC. Considering the four dimensions of adequacy, we found that having only one dimension was associated with a relative risk ratio (RRR) of 12.45 (95% CI: 6.40, 24.23), while having two or three dimensions was associated with a RRR of 5.23 (95% CI: 2.83, 9.65) when using adequate ANC as the category of reference.ConclusionsAccording to our results, Indigenous women's ANC adequacy was negatively affected by the COVID‐19 pandemic. In light of these findings, we emphasize the importance of developing healthcare systems that are prepared to adapt consultation schemes by implementing virtual visits and incorporating community health workers.
Systematic review and meta‐analysis examining the effects of midwife care on cesarean birth
Authors: Hoxha Ilir , Grezda Krenare , Udutha Anirudh , Taganoviq Besarta , Agahi Riaz , Brajshori Naime , Rising Sharon Schindler 
Published: December 2023

AbstractBackgroundThe increasing number of unnecessary cesarean births is a cause for concern and may be addressed by increasing access to midwifery care. The objective of this review was to assess the effect of midwifery care on the likelihood of cesarean births.MethodsWe searched five databases from the beginning of records through May 2020. We included observational studies that reported odds ratios or data allowing the calculation of odds ratios of cesarean birth for births with and without midwife involvement in care or presence at the institution. Standard inverse‐variance random‐effects meta‐analysis was used to generate overall odds ratios (ORs).ResultsWe observed a significantly lower likelihood of cesarean birth in midwife‐led care, midwife‐attended births, among those who received instruction pre‐birth from midwives, and within institutions with a midwifery presence.ConclusionsCare from midwives reduces the likelihood of cesarean birth in all the analyses, perhaps due to their greater preference and skill for physiologic births. Increased use of midwives in maternal care can reduce cesarean births and should be further researched and implemented broadly, potentially as the default modality in maternal care.
Variations over time in mode of birth and perinatal outcomes in women with one previous cesarean in the Netherlands: A 20‐year population‐based study
Authors: Koorn Ian , Vis Linda C. , Verschueren Kim J. C. , Rosman Ageeth N. , van den Akker Thomas 
Published: December 2023

AbstractBackgroundGlobally, cesarean birth rates are rising, and while it can be a lifesaving procedure, cesarean birth is also associated with increased maternal and perinatal risks. This study aims to describe changes over time about the mode of birth and perinatal outcomes in second‐pregnancy women with one previous cesarean birth in the Netherlands over the past 20 years.MethodsWe conducted a nationwide, population‐based study using the Dutch perinatal registry. The mode of birth (intended vaginal birth after cesarean (VBAC) compared with planned cesarean birth) was assessed in all women with one previous cesarean birth and no prior vaginal birth who gave birth to a term singleton in cephalic presentation between 2000 and 2019 in the Netherlands (n = 143,146). The reported outcomes include the trend of intended VBAC, VBAC success rate, and adverse perinatal outcomes (perinatal mortality up to 7 days, low Apgar score at 5 min, asphyxia, and neonatal intensive care unit admission ≥24 h).ResultsIntended VBAC decreased by 21.5% in women with one previous cesarean birth and no prior vaginal birth, from 77.2% in 2000 to 55.7% in 2019, with a marked deceleration from 2009 onwards. The VBAC success rate dropped gradually, from 71.0% to 65.3%, across the same time period. Overall, the cesarean birth rate (planned and unplanned) increased from 45.2% to 63.6%. Adverse perinatal outcomes were higher in women intending VBAC compared with those planning a cesarean birth. Perinatal mortality initially decreased but remained stable from 2009 onwards, with only minimal differences between both modes of birth.ConclusionsIn the Netherlands, the proportion of women intending VBAC after one previous cesarean birth and no prior vaginal birth has decreased markedly. Particularly from 2009 onwards, this decrease was not accompanied by a synchronous reduction in perinatal mortality.
Bridging treatment prior to chimeric antigen receptor T‐cell therapy in multiple myeloma
Authors: Bal Susan , Costa Luciano J. 
Published: December 2023

SummaryAutologous patient‐derived adoptive T‐cell therapies have revolutionized the management of relapsed multiple myeloma (MM). However, the current manufacturing and quality control processes result in lengthy vein‐to‐vein time, making bridging therapy necessary for most patients. Yet the decision and choice of optimal bridging therapy are complex in the heavily pretreated relapsed MM patient. In this perspective piece, the authors provide their approach and considerations while selecting an optimal bridging regimen before autologous chimeric antigen receptor T‐cell therapy.
The effective sample size in Bayesian information criterion for level‐specific fixed and random‐effect selection in a two‐level nested model
Authors: Cho Sun‐Joo , Wu Hao , Naveiras Matthew 
Published: December 2023

AbstractPopular statistical software provides the Bayesian information criterion (BIC) for multi‐level models or linear mixed models. However, it has been observed that the combination of statistical literature and software documentation has led to discrepancies in the formulas of the BIC and uncertainties as to the proper use of the BIC in selecting a multi‐level model with respect to level‐specific fixed and random effects. These discrepancies and uncertainties result from different specifications of sample size in the BIC's penalty term for multi‐level models. In this study, we derive the BIC's penalty term for level‐specific fixed‐ and random‐effect selection in a two‐level nested design. In this new version of BIC, called , this penalty term is decomposed into two parts if the random‐effect variance–covariance matrix has full rank: (a) a term with the log of average sample size per cluster and (b) the total number of parameters times the log of the total number of clusters. Furthermore, we derive the new version of BIC, called , in the presence of redundant random effects. We show that the derived formulae, and , adhere to empirical values via numerical demonstration and that ( indicating either or ) is the best global selection criterion, as it performs at least as well as BIC with the total sample size and BIC with the number of clusters across various multi‐level conditions through a simulation study. In addition, the use of is illustrated with a textbook example dataset.
Positive association between adiposity and inflammation in US adults: A cross‐sectional study
Authors: Ferrell Koya , Brown Isaiah , Amare Abel , McNeel Timothy S. , Buckman Dennis , Jackson Sharon H. 
Published: December 2023

SummaryIdentification of biomarkers involved in multifaceted obesity‐related inflammatory processes paired with reliable anthropometric measures of visceral adiposity is important for developing epidemiologic screening tools. This retrospective observational study used linear regression models to examine the association between inflammation and visceral fat in a nationally representative sample of 10 655 US adults. Inflammation was measured using a cumulative inflammation index (CII) generated from white blood cell ratios and uric acid. Intra‐abdominal adiposity was assessed using sagittal abdominal diameter (SAD). Overall, 67.7%, 18.3%, and 13.9% of adults sampled were normoglycemic, prediabetic, and diabetic, with mean SAD of 21.7 ± 0.11 cm, 24.2 ± 0.14 cm, 26.0 ± 0.18 cm and CII of 4.3 ± 0.05, 4.7 ± 0.09, 5.1 ± 0.09, respectively. For each unit increase in SAD, CII was 0.12 higher (95% CI 0.10, 0.14) in US adults who were normoglycemic, 0.09 higher (95% CI 0.07, 0.12) in prediabetics and 0.10 higher (95% CI 0.07, 0.14) in diabetics. The association between SAD and CII was independent of diabetes status. These findings demonstrate an independent association between adiposity and inflammation, supporting increased visceral fat is associated with increased visceral‐associated inflammation. Future studies are needed to define and characterise obesity‐related inflammatory mediators and their role in chronic disease risk such as diabetes.
Home recording of 3‐Hz spike–wave discharges in adults with absence epilepsy using the wearable Sensor Dot
Authors: Swinnen Lauren , Chatzichristos Christos , Bhagubai Miguel , Broux Victoria , Zabler Nicolas , Dümpelmann Matthias , Schulze‐Bonhage Andreas , De Vos Maarten , Van Paesschen Wim 
Published: December 2023

AbstractObjectiveHome monitoring of 3‐Hz spike–wave discharges (SWDs) in patients with refractory absence epilepsy could improve clinical care by replacing the inaccurate seizure diary with objective counts. We investigated the use and performance of the Sensor Dot (Byteflies) wearable in persons with absence epilepsy in their home environment.MethodsThirteen participants (median age = 22 years, 11 female) were enrolled at the university hospitals of Leuven and Freiburg. At home, participants had to attach the Sensor Dot and behind‐the‐ear electrodes to record two‐channel electroencephalogram (EEG), accelerometry, and gyroscope data. Ground truth annotations were created during a visual review of the full Sensor Dot recording. Generalized SWDs were annotated if they were 3 Hz and at least 3 s on EEG. Potential 3‐Hz SWDs were flagged by an automated seizure detection algorithm, (1) using only EEG and (2) with an additional postprocessing step using accelerometer and gyroscope to discard motion artifacts. Afterward, two readers (W.V.P. and L.S.) reviewed algorithm‐labeled segments and annotated true positive detections. Sensitivity, precision, and F1 score were calculated. Patients had to keep a seizure diary and complete questionnaires about their experiences.ResultsTotal recording time was 394 h 42 min. Overall, 234 SWDs were captured in 11 of 13 participants. Review of the unimodal algorithm‐labeled recordings resulted in a mean sensitivity of .84, precision of .93, and F1 score of .89. Visual review of the multimodal algorithm‐labeled segments resulted in a similar F1 score and shorter review time due to fewer false positive labels. Participants reported that the device was comfortable and that they would be willing to wear it on demand of their neurologist, for a maximum of 1 week or with intermediate breaks.SignificanceThe Sensor Dot improved seizure documentation at home, relative to patient self‐reporting. Additional benefits were the short review time and the patients' device acceptance due to user‐friendliness and comfortability.
Divine trauma: Schizophrenia and unresolved realities in South India
Authors: Bala Anjana 
Published: December 2023

AbstractThis article explores the relationship between schizophrenia, divine encounters, and therapeutics based on ethnographic research in Chennai, Tamil Nadu, India. Contributing to a long history of single‐subject ethnographies in psychological anthropology, this article narrates the events leading up to the diagnosis and the emerging life worlds post‐diagnosis of an interlocutor I call Dhruv. I depart from symbolic constructions of the divine to an affective divine, a kind of force that enters and alters embodied existence. Following scholars who call for theories that move beyond Western metropolitan epistemologies, I draw upon the Bhagavad Gita, a poetic scripture from the Hindu tradition, as a form of psychological theory to contend how an encounter with the divine might be too much to bear, even traumatic. In doing so, the article offers an alternative entry point to the commonly held assumption of the therapeutic efficacy of divine encounters and religious sites in India.
Effect of pre–shearing regimes on rheological parameters of cement paste
Authors: Feng Kaiwen , Li Wenxu , Ma Kunlin , Yu Lianshan , Zou Weidong , Long Guangcheng 
Published: December 2023

AbstractIn rheological testing, different test regimes can result in large differences in the rheological curves, and the pre‐shear procedure is one of the most important parts of the test. In order to investigate the effect of the pre‐shear regime on the rheological properties of cement pastes, an Anton Paar 102 rotary rheometer was used for the test. Two different pre‐shear regimes (RF and CP pre‐shear), three different pre‐shear duration times (50 s, 100 s, 150 s), and four different pre‐shear rates (25 s−1, 50 s−1, 100 s−1) are carried out for the test. The results showed that with the increase of pre‐shear duration or rate, the four rheological parameters (plastic viscosity, yield stress, rheological index, and thixotropy) of the pastes decrease in different degrees. RF pre‐shear was more influenced by shear time, while CP pre‐shear was influenced by shear time and rate. The pre‐shear regimes led to different changes in the flocculation structure of the cement paste, which had a great influence on rheological parameters ultimately. Based on the improved Krieger‐Dougherty model, the effective solid volume fraction of cement paste was calculated. Analysis shows that the phenomenon of “deflocculation” and “re‐flocculation” occurs when the cement paste is subjected to shear action, thus, the pre‐shear regimes destroy the structure of the pastes. With the increase of pre‐shear duration or rate, the effective volume fraction decreased, which indicated that the initial flocculation structure was broken. The greater the damage degree of pre‐shear, the slower the establishment rate of the internal structure of the pastes in dynamic shear, resulting in lower rheological parameters.
Geriatric Interprofessional Team Transformation for Primary Care overview
Authors: Flaherty Ellen , O'Connor Sharon , Steltenpohl Crystal N. , Preiss Michaela , Volckaert Annaliese , Pepin Renée L. 
Published: December 2023

AbstractBackgroundThe Geriatric Interprofessional Team Transformation for Primary Care (GITT‐PC) is a model developed to deliver optimal care to older adults in primary care. GITT‐PC is an expansion of the John A. Hartford Foundation Geriatric Interdisciplinary Team Training (GITT) program developed at New York University and funded from 1995 to 2002 (Fulmer et al., 2004). GITT was designed to create training models that reflect the needs of the changing health care system and the challenge of caring for older adults with complex conditions (Fulmer et al., 2005). The GITT‐PC model builds on the lessons learned from GITT and the development of curricula and training materials based on best practices.MethodsImplementation of GITT‐PC is accomplished through systems and practices that meet the needs and preferences of patients and their families and that are implemented by teams of health professionals and community service providers. GITT‐PC is focused on four core components of high‐quality geriatric care: (1) health promotion and prevention, (2) chronic disease management, (3) advanced care planning, and (4) transitional care management, each component corresponding to a Medicare‐reimbursable visit.ResultsImplementation of these reimbursable services enables practices to provide evidence‐based geriatric care while realizing a potential significant return on investment.ConclusionsThe GITT‐PC model has evolved from an academic training program to a financially sustainable model that serves to improve the care of older adults through a systematic team transformation process that makes a clear business case for primary care (Tabbush et al., 2021). The GITT‐PC training program can be implemented in primary care practices with a focus on improving or expanding delivery of annual wellness visits (AWVs) and, potentially, registered RN‐led AWVs.