bluuebunny/crossref_metadata_2025_split huggingface dataset:
Toward a Synergistic Optimization of Porous Electrode Formulation and Polysulfide Regulation in Lithium–Sulfur Batteries
Authors: Yari Saeed , Henderick Lowie , Choobar Behnam Ghalami , Detavernier Christophe , Safari Mohammadhosein 
Published: December 2023

AbstractThe use of functional materials is a popular strategy to mitigate the polysulfide‐induced accelerated aging of lithium–sulfur (Li‐S) batteries. However, deep insights into the role of electrode design and formulation are less elaborated in the available literature. Such information is not easy to unearth from the existing reports on account of the scattered nature of the data and the big dissimilarities among the reported materials, preparation protocols, and cycling conditions. In this study, model functional materials known for their affinity toward polysulfide species, are integrated into the porous sulfur electrodes at different quantities and with various spatial distributions. The electrodes are assembled in 240 lithium–sulfur cells and thoroughly analyzed for their short‐ and long‐term electrochemical performance. Advanced data processing and visualization techniques enable the unraveling of the impact of porous electrodes’ formulation and design on self‐discharge, sulfur utilization, and capacity loss. The results highlight and quantify the sensitivity of the cell performance to the synergistic interactions of catalyst loading and its spatial positioning with respect to the sulfur particles and carbon‐binder domain. The findings of this work pave the road for a holistic optimization of the advanced sulfur electrodes for durable Li–S batteries.
Strategies for Enhancing the Photocatalytic and Electrocatalytic Efficiency of Covalent Triazine Frameworks for CO2 Reduction
Authors: Liu Gang , Liu Shaobo , Lai Cui , Qin Lei , Zhang Mingming , Li Yixia , Xu Mengyi , Ma Dengsheng , Xu Fuhang , Liu Shiyu , Dai Mingyang , Chen Qiang 
Published: December 2023

AbstractConverting carbon dioxide (CO2) into fuel and high‐value‐added chemicals is considered a green and effective way to solve global energy and environmental problems. Covalent triazine frameworks (CTFs) are extensively utilized as an emerging catalyst for photo/electrocatalytic CO2 reduction reaction (CO2RR) recently recognized for their distinctive qualities, including excellent thermal and chemical stability, π‐conjugated structure, rich nitrogen content, and a strong affinity for CO2, etc. Nevertheless, single‐component CTFs have the problems of accelerated recombination of photoexcited electron‐hole pairs and restricted conductivity, which limit their application for photo/electrocatalytic CO2RR. Therefore, emphasis will then summarize the strategies for enhancing the photocatalytic and electrocatalytic efficiency of CTFs for CO2RR in this paper, including atom doping, constructing a heterojunction structure, etc. This review first illustrates the synthesis strategies of CTFs and the advantages of CTFs in the field of photo/electrocatalytic CO2RR. Subsequently, the mechanism of CTF‐based materials in photo/electrocatalytic CO2RR is described. Lastly, the challenges and future prospects of CTFs in photo/electrocatalytic CO2RR are addressed, which offers a fresh perspective for the future development of CTFs in photo/electrocatalytic CO2RR.
Stopping Microfluidic Flow
Authors: Sahin Mehmet Akif , Shehzad Muhammad , Destgeer Ghulam 
Published: December 2023

AbstractA cross‐comparison of three stop‐flow configurations—such as low‐pressure (LSF), high‐pressure open‐circuit (OC‐HSF), and high‐pressure short‐circuit (SC‐HSF) stop‐flow—is presented to rapidly bring a high velocity flow O(m s−1) within a microchannel to a standstill O(µm s−1). The performance of three stop‐flow configurations is assessed by measuring residual flow velocities within microchannels having three orders of magnitude different flow resistances. The LSF configuration outperforms the OC‐HSF and SC‐HSF configurations within a high flow resistance microchannel and results in a residual velocity of <10 µm s−1. The OC‐HSF configuration results in a residual velocity of <150 µm s−1 within a low flow resistance microchannel. The SC‐HSF configuration results in a residual velocity of <200 µm s−1 across the three orders‐of‐magnitude different flow resistance microchannels, and <100 µm s−1 for the low flow resistance channel. It is hypothesized that residual velocity results from compliance in fluidic circuits, which is further investigated by varying the elasticity of microchannel walls and connecting tubing. A numerical model is developed to estimate the expanded volumes of the compliant microchannel and connecting tubings under a pressure gradient and to calculate the distance traveled by the sample fluid. A comparison of the numerically and experimentally obtained traveling distances confirms the hypothesis that the residual velocities are an outcome of the compliance in the fluidic circuit.
Heteroepitaxial Growth to Construct Hexagonal/Hexagonal β‐NaYF4:Yb,Tm/Cs4PbBr6 Multi‐Code Emitting Core/Shell Nanocrystals
Authors: Gao Rui , Xu Wanqing , Wang Zhiqing , Li Fen , Liu Yueli , Li Guogang , Chen Keqiang 
Published: December 2023

AbstractSynthesis of upconversion nanoparticles (UCNPs)‐metal halide perovskites (MHPs) heterostructure is garnered immense attentions due to their unparalleled photophysical properties. However, the obvious difference in their structural forms makes it a huge challenge. Herein, hexagonal β‐NaYF4 and hexagonal Cs4PbBr6 are filtrated to construct the UCNP/MHP heterostructural luminescent material. The similarity in their crystal structures facilitate the heteroepitaxial growth of Cs4PbBr6 on the surface of β‐NaYF4 NPs, leading to the formation of high‐quality β‐NaYF4:Yb,Tm/Cs4PbBr6 core/shell nanocrystals (NCs). Interestingly, this heterostructure endows the core/shell NCs with typically narrow‐band green emission centered at 524 nm under 980 nm excitation, which should be attributed to the Förster resonance energy transfer (FRET) from Tm3+ to Cs4PbBr6. It is noteworthy that the FRET efficiency of β‐NaYF4:Yb,Tm/Cs4PbBr6 core/shell NCs (58.33%) is much higher than that of the physically mixed sample (1.84%). In addition, the reduced defect density, lattice anchoring effect, as well as diluted ionic bonding proportion induced by the core/shell structure further increase the excellent water‐resistance and thermal cycling stability of Cs4PbBr6. These findings open up a new way to construct UCNP/MHP heterostructure with better multi‐code luminescence performance and stability and promote its wide optoelectronic applications.
Osteoporotic Bone Regeneration via Plenished Biomimetic PLGA Scaffold with Sequential Release System
Authors: Lee Jun‐Kyu , Kim Da‐Seul , Park So‐Yeon , Jung Ji‐Won , Baek Seung‐Woon , Lee Semi , Kim Jun Hyuk , Ahn Tae‐Keun , Han Dong Keun 
Published: December 2023

AbstractAchieving satisfactory bone tissue regeneration in osteoporotic patients with ordinary biomaterials is challenging because of the decreased bone mineral density and aberrant bone microenvironment. In addressing this issue, a biomimetic scaffold (PMEH/SP), incorporating 4‐hexylresorcinol (4HR), and substance P (SP) into the poly(lactic‐go‐glycolic acid) (PLGA) scaffold with magnesium hydroxide (M) and extracellular matrix (E) is introduced, enabling the consecutive release of bioactive agents. 4HR and SP induced the phosphorylation of p38 MAPK and ERK in human umbilical vein endothelial cells (HUVECs), thereby upregulating VEGF expression level. The migration and tube‐forming ability of endothelial cells can be promoted by the scaffold, which accelerates the formation and maturation of the bone. Moreover, 4HR played a crucial role in the inhibition of osteoclastogenesis by interrupting the IκB/NF‐κB signaling pathway and exhibiting SP, thereby enhancing the migration and angiogenesis of HUVECs. Based on such a synergistic effect, osteoporosis can be suppressed, and bone regeneration can be achieved by inhibiting the RANKL pathway in vitro and in vivo, which is a commonly known mechanism of bone physiology. Therefore, the study presents a promising approach for developing a multifunctional regenerative material for sophisticated osteoporotic bone regeneration.
The ABCs of appreciative‐based change: An appreciative service‐learning model
Authors: Poteet Christie 
Published: December 2023

AbstractThe Appreciative‐Based Change (ABC) Model of Community Engagement focuses on strengthening partnerships and maximizing impact by using an appreciative approach to service‐learning while addressing the challenges of community‐university partnerships. The model offers phases that identify and leverage unified strengths, assets, and resources to create positive change.
Appreciative administration in action: How the appreciative education theory‐to‐practice framework is being infused into higher education administrative practices
Authors: Elsberry Meagan , Bloom Jennifer L. , Cuevas Amanda Propst , Beorchia Mykel 
Published: December 2023

AbstractToday's higher education leaders are tasked with devising creative solutions to issues under formidable circumstances. Appreciative Administration offers a creative theory‐to‐practice framework to help higher education organizations thrive. The purpose of this article is to provide an updated definition and explore practical applications of the Appreciative Administration theory‐to‐practice framework.
A Fractional‐Order Kinetics Approach for Modeling Enzymatic Starch Multiscale Digestion
Authors: Alvarez‐Ramirez Jose , Vernon‐Carter Eduardo Jaime , Bello‐Perez Luis A. 
Published: December 2023

AbstractThe characterization of the enzymatic hydrolysis of starch is a prerequisite for assessing the impact of starchy food in the gastrointestinal tract. The issue is relevant given the necessity of tailoring food products with a prescribed capacity of glucose production. Several empirical functions have been proposed for modeling starch digestograms. The first‐order exponential and the Weibull models are among the most used functions. Although tight numerical fitting of the experimental data may be obtained with such functions, a reliable interpretation of the underlying parameters is commonly a drawback. This work explores the use of fractional‐order kinetics for the modeling of starch digestograms. The aims are to show that: a) the fractional‐order framework offers a framework for capturing multiscale patterns observed, and b) the Weibull's and Peleg's models are particular cases of a more general function expressed as a generalized (Mittag‐Leffler) exponential function. The results showed that the Mittag–Leffler exponential function provided the best‐fitting results. However, the gain relative to Weibull's and fractional Peleg's functions may be small. It is concluded that Weibull's function approximates a more general function (the Mittag‐Leffler function), and as such its parameters find an easier interpretation in terms of the hydrolysis kinetics.
A novel lead‐free relaxor with endotaxial nanostructures for capacitive energy storage
Authors: Dong Xiaoyan , Hu Tengfei , Wu Xiaojun , Yin Jie , Fu Zhengqian , Wu Jiagang 
Published: December 2023

AbstractDielectric capacitors with a fast charging/discharging rate, high power density, and long‐term stability are essential components in modern electrical devices. However, miniaturizing and integrating capacitors face a persistent challenge in improving their energy density (Wrec) to satisfy the specifications of advanced electronic systems and applications. In this work, leveraging phase‐field simulations, we judiciously designed a novel lead‐free relaxor ferroelectric material for enhanced energy storage performance, featuring flexible distributed weakly polar endotaxial nanostructures (ENs) embedded within a strongly polar fluctuation matrix. The matrix contributes to substantially enhanced polarization under an external electric field, and the randomly dispersed ENs effectively optimize breakdown phase proportion and provide a strong restoring force, which are advantageous in bolstering breakdown strength and minimizing hysteresis. Remarkably, this relaxor ferroelectric system incorporating ENs achieves an exceptionally high Wrec value of 10.3 J/cm3, accompanied by a large energy storage efficiency (η) of 85.4%. This work introduces a promising avenue for designing new relaxor materials capable of capacitive energy storage with exceptional performance characteristics.
Lessons from 2019–2020 Landslide Risk Assessment in an Urban Area of Volcanic Soils in Pereira-Colombia
Authors: Ríos Diego , Ávila Guillermo 
Published: December 2023

AbstractThe city of Pereira is in the central-western region of Colombia, in the valley of the Otún River in the Central Cordillera of the Colombian Andes, whose soils are mostly composed of volcanic ash and Lahar flows. On June 11, 2019, after intense rains, a landslide of about 13,000 m3 was triggered. This landslide killed 4 people, interrupted the traffic on an important national road, and endangered the airport runway. Just after the event, it was necessary to evacuate 100 homes, located in the upper part of the slope and 234 in the following days. A second landslide occurred on July 24, 2020, mobilizing 52,000 m3 and affecting 33 of the previously evacuated houses, then there were about 20 more small landslides. A zone of about 2.300 m long and 300 m wide (69 ha) was identified to be susceptible to new landslides that may affect more than 15.000 people. Identification of landslide triggering factors, failure, post-failure behavior, and the retrogressive landslide advance are reviewed because they are key factors for an effective hazard evaluation and risk governance. The landslide event was also used to calibrate a general methodological guide for landslide risk assessment, developed by the Colombian Geological Service and the National University of Colombia (Ávila et al. 2016) that has been extensively applied for the inclusion of risk evaluation in the land use planning, as required by the Colombian legislation.
A novel approach for gingiva thickness measurements around lower anterior teeth by means of dental magnetic resonance imaging
Authors: Schwarz Linda , Unger Ewald , Gahleitner André , Rausch-Fan Xiaohui , Jonke Erwin 
Published: December 2023

Abstract
Objective
This diagnostic accuracy study aims to present the first measurements of gingiva thickness around lower anterior teeth using dental magnetic resonance imaging (MRI) and to compare these measurements with two established methods: (1) gingival phenotype assessment via periodontal probing, and (2) the superimposition of cone-beam computed tomography (CBCT) scans with intraoral scans of teeth and gums.

Materials and methods
Ten patients with substantial orthodontic treatment need and anterior mandibular crowding were consecutively included in this clinical case series. After periodontal probing, each patient underwent a CBCT scan, an intraoral scan of the mandible, and an MRI investigation using a novel mandibula 15-channel dental coil.

Results
The mean gingiva thickness was 0.72 mm measured on MRI and 0.97 mm measured on CBCT, with a mean difference between the measurement methods of 0.17 ± 0.27 mm (p < 0.001). Measurement agreement between the index tests (MRI and CBCT) and the clinical reference standard (probing) yielded an overall percent agreement of 64.94% and 47.02% for MRI and CBCT, respectively. Teeth with thin phenotypes were associated with lower soft tissue dimensions in both free (MRI: 0.56 mm vs. CBCT: 0.79 mm) and supracrestal gingiva (MRI: 0.75 mm vs. CBCT: 1.03 mm) when compared to those with thick phenotypes. However, only the measurements obtained from MRI scans showed statistically significant differences between the two phenotypes.

Conclusion
Dental MRI successfully visualizes delicate structures like the gingiva in the anterior mandible and achieves a high correlation with superimposed CBCT scans, with clinically acceptable deviations.

Clinical relevance
The present study helps to establish dental MRI as a radiation-free alternative to conventional radiographic methods.
ToRaRI (Tofacitinib in Rheumatoid Arthritis a Real-Life experience in Italy): Effectiveness, safety profile of tofacitinib and concordance between patient-reported outcomes and physician's global assessment of disease activity in a retrospective study in Central-Italy
Authors: D’Alessandro Francesco , Cazzato Massimiliano , Laurino Elenia , Morganti Riccardo , Bardelli Marco , Frediani Bruno , Buongarzone Claudia , Moroncini Gianluca , Guiducci Serena , Cometi Laura , Benucci Maurizio , Ligobbi Francesca , Marotto Daniela , Mosca Marta 
Published: December 2023

Abstract
Introduction
The use of Janus Kinase Inhibitors (JAK-Is) in rheumatoid arthritis (RA) has entered in daily practice. In consideration of ORAL-Surveillance trial and the new EULAR recommendations, real-world data are needed to assess Jak-Is safety and effectiveness. The multicenter study presented here aimed to evaluate effectiveness and safety of tofacitinib in a real-life cohort.

Methods
A retrospective analysis was performed from September 2021 to December 2022. Data were collected when tofacitinib was started (T0) and after 3 (T3), 6 (T6) and 12 (T12) months of treatment. The primary objective was to analyze the efficacy and safety of tofacitinib. Safety was assessed by recording adverse events (AEs) with and without discontinuation.
The secondary objective was to assess the difference between Patient-Reported Outcomes (PROs) and Physician's Global Assessment of disease activity (PhGA).

Results
122 patients were included in the study from the following rheumatology Centers: Pisa, Ancona, Florence (two Centers), Siena, and Sardinia. A statistically significant improvement in DAS-28-CRP, CDAI and SDAI score was observed at T3, T6, compared to baseline (p < 0.001). Improvement was confirmed in patients who reach T12. Patients naïve to bDMARDs showed a shorter remission time and higher remission rates. There was also a statistically significant improvement in PROs compared to baseline (p < 0.001). The improvement was rapid and was consistent with PhGA. The 12-month retention rate for tofacitinib was 89.35%. Reasons to stop tofacitinib were: insufficient response (7), gastrointestinal symptoms (2), infection (1), malignancy (1), Zoster (1), pruritus sine materia (1).

Conclusions
Tofacitinib is safe and effective in our RA cohort. It induces higher remission rates in patients naive to bDMARDs, suggesting that there may be a benefit using it as first-line therapy. Additionally, improvement in PROs was consistent with PhGA scores, demonstrating how tofacitinib affects both the objective and subjective components of disease activity.

Key Points1. JAK inhibitors are considered at a similar level as biologic agents in terms of effectiveness.2. After ORAL-Surveillance results, real-world data are needed to assess the benefit/risk profile of Jaki.3. Disagreement between patients and physicians has been previously reported with biologic therapy among patients with rheumatoid arthritis, with patients rating disease activity higher than physicians.4. Jak inhibitors could reduce this discrepancy, due to their mechanism of action.
Air quality and cancer risk in the All of Us Research Program
Authors: Craver Andrew , Luo Jiajun , Kibriya Muhammad G. , Randorf Nina , Bahl Kendall , Connellan Elizabeth , Powell Johnny , Zakin Paul , Jones Rena R. , Argos Maria , Ho Joyce , Kim Karen , Daviglus Martha L. , Greenland Philip , Ahsan Habibul , Aschebrook-Kilfoy Briseis 
Published: December 2023

Abstract
Introduction
The NIH All of Us Research Program has enrolled over 544,000 participants across the US with unprecedented racial/ethnic diversity, offering opportunities to investigate myriad exposures and diseases. This paper aims to investigate the association between PM2.5 exposure and cancer risks.

Materials and methods
This work was performed on data from 409,876 All of Us Research Program participants using the All of Us Researcher Workbench. Cancer case ascertainment was performed using data from electronic health records and the self-reported Personal Medical History questionnaire. PM2.5 exposure was retrieved from NASA’s Earth Observing System Data and Information Center and assigned using participants’ 3-digit zip code prefixes. Multivariate logistic regression was used to estimate the odds ratio (OR) and 95% confidence interval (CI). Generalized additive models (GAMs) were used to investigate non-linear relationships.

Results
A total of 33,387 participants and 46,176 prevalent cancer cases were ascertained from participant EHR data, while 20,297 cases were ascertained from self-reported survey data from 18,133 participants; 9,502 cancer cases were captured in both the EHR and survey data. Average PM2.5 level from 2007 to 2016 was 8.90 μg/m3 (min 2.56, max 15.05). In analysis of cancer cases from EHR, an increased odds for breast cancer (OR 1.17, 95% CI 1.09–1.25), endometrial cancer (OR 1.33, 95% CI 1.09–1.62) and ovarian cancer (OR 1.20, 95% CI 1.01–1.42) in the 4th quartile of exposure compared to the 1st. In GAM, higher PM2.5 concentration was associated with increased odds for blood cancer, bone cancer, brain cancer, breast cancer, colon and rectum cancer, endocrine system cancer, lung cancer, pancreatic cancer, prostate cancer, and thyroid cancer.

Conclusions
We found evidence of an association of PM2.5 with breast, ovarian, and endometrial cancers. There is little to no prior evidence in the literature on the impact of PM2.5 on risk of these cancers, warranting further investigation.
Discerning Philosophy in the Uttarāmnāya Liturgies of the Newars
Authors: Pangsrivongse Pongsit 
Published: December 2023

AbstractAlthough the Kaula literature of the Newars did not give rise to a systematic philosophical school like that of their Kashmiri counterparts, I will argue in this article that philosophical thinking can be detected in Newar ritual texts. I do this by translating and analysing the unpublished Kālīsūtra, an important hymn found in Newar Uttarāmnāya liturgies whose transmission and composition will also be touched upon. This hymn indicates that the cult of Kālī in Nepal had a distinct ontological stance tending towards a non-dualism which was world-affirming while also seeing consciousness as the ultimate reality. Several key conceptual strands of the Sūtra such as the relationship between transcendence and immanence, reality and cognition and the divine and the body will be elaborated upon. In the process, I will show that the Kālīsūtra’s philosophy brings into sharper focus doctrines already present in the canonical Krama and thus displays many affinities with the Pratyabhijñā, a school which shares its cultic backdrop.
Microbiome and pregnancy: focus on microbial dysbiosis coupled with maternal obesity
Authors: Beckers Kalie F. , Flanagan Juliet P. , Sones Jenny L. 
Published: December 2023

AbstractObesity is becoming a worldwide pandemic with over one billion people affected. Of women in the United States, who are of childbearing age, two-thirds of them are considered overweight/obese. Offspring of women with obesity have a greater likelihood of developing cardiometabolic disease later in life, therefore making obesity a transgenerational issue. Emerging topics such as maternal microbial dysbiosis with altered levels of bacterial phyla and maternal obesity programming offspring cardiometabolic disease are a novel area of research discussed in this review. In the authors’ opinion, beneficial therapeutics will be developed from knowledge of bacterial-host interactions at the most specific level possible. Although there is an abundance of obesity-related microbiome research, it is not concise, readily available, nor easy to interpret at this time. This review details the current knowledge regarding the relationship between obesity and the gut microbiome, with an emphasis on maternal obesity.