bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the role of vitamin D in patients with psoriasis
Authors: Pedon Isabel Caroline Zanatta , Fim Gabriela Martins , Libera Nathalia Kaminski Della , Mattos Alexandra Brugnera Nunes de 
Published: November 2023

Objectives: Investigate whether there is any association between the levels of vitamin D in the blood and the seriousness of psoriasis or its development. Methods: The study is characterized as observational, retrospective, composed of 40 patients with psoriasis who had serum vitamin D levels, who underwent clinical care at a dermatology outpatient clinic in Passo Fundo/RS, from August 2019 to June 2021. Results: Of the 40 interviewees, 60% were female and 40% male. Phototypes II and III prevailed. Regarding family health history, 50% had a history of the disease. Regarding the duration of psoriasis, the predominant group was between 1-10 years (57.5%). The most prevalent psoriasis subtype was vulgaris (62.5%). Regarding serum vitamin D results, the lowest index was 15.2 ng ̸ mL, the highest was 42.3 ng ̸ mL and the average was 25.99 ng ̸mL. In the predominant age group, between 20-40 years, the proportion of patients with vitamin D was less than 30 ng ̸mL is 83.33%. The lower the phototype, the greater the proportion of patients with suboptimal serum vitamin D. In the group of patients with disease duration > 10 years, vitamin D levels were lower. There is no extreme difference in the effectiveness of treatments when analyzing the average, minimum and maximum serum levels of vitamin D. Conclusion: There was no relationship between serum levels of 25-hydroxyvitamin D (25OHD) and the development of psoriasis or even control – worsening of the clinical picture of disease.
Farmacoterapia e resistência antimicrobiana em pacientes hospitalizados em unidade de terapia intensiva
Authors: Antunes Neoraldo Junior , Souza Anthony Gabriel Pusini de , Silva Claudinei Mesquita da , Peder Leyde Daiane de 
Published: November 2023

O presente estudo visa identificar o perfil de resistência antibacteriana na farmacoterapia utilizada em pacientes de uma Unidade de Terapia Intensiva (UTI), de um hospital particular de Cascavel – PR. Como objetivo, tem-se a identificação das principais bactérias resistentes, a antibioticoterapia utilizada e definição do perfil de resistência, dos microrganismos identificados. Este estudo se caracteriza como observacional transversal retrospectivo, elaborado a partir de exames realizados em pacientes internados em uma UTI de um hospital particular de Cascavel – PR, no período de 2020 a 2021. Teve como resultados, uma maior prevalência de infecção em pacientes do sexo masculino (65,42%) e um maior índice de casos a partir de 49 anos de idade. A amostra biológica utilizada, em ambos os anos analisados foi de secreção traqueal com 61,82% em 2020 e 48,08% em 2021.e um total de 14 espécies de bactérias isoladas. Observou-se uma prevalência da Klebsiella pneumoniae com 36,64% do total de culturas positivas no período, seguida por Pseudomonas aeruginosa (18,69%) e Staphylococcus aureus (11,21%). Em relação à resistência aos antibióticos, a K. pneumoniae apresentou uma média de 62% aos medicamentos utilizados no seu tratamento, acompanhada por P. aeruginosa com 57% de média de resistência, e S. aureus apresentou 73,5%. A grande prevalência de resistência aos antibióticos na UTI desta instituição, sugere a necessidade de melhoria na vigilância e controle das infecções, este estudo oferece dados para melhoria da prática clínica bem como da gestão de infecções no setor de internamento.
Poliomielite: As causas para a queda da cobertura vacinal no Brasil
Authors: Lima Felipe de Souza , Martins Maria Eduarda Faria , Rennó Giseli Mendes , Gonzaga Vanderléa Aparecida Silva 
Published: November 2023

Introdução: Desde 1994, o Brasil manteve o compromisso de não permitir a reintrodução do vírus da pólio em seu território, com uma meta vacinal de 95% da população. No entanto, desde 2016, essa meta não tem sido atingida, o que levou a uma queda preocupante na cobertura vacinal. Isso pode ser atribuído à pandemia de COVID-19, ao movimento antivacina e à implementação de políticas de austeridade na saúde e educação. Objetivo: Identificar as causas para a queda da cobertura vacinal de poliomielite apresentadas nos estudos científicos. Métodos: Trata-se de uma revisão narrativa da literatura que foi realizada através das bases de dados Lilacs, Scielo, Pubmed e BVS. Foram selecionados artigos compatíveis com os critérios de inclusão: estudos realizados entre 2018 a 2023, em inglês e português, completos e disponíveis para consulta. Foram excluídos documentos que não se encaixavam nos critérios estabelecidos. Resultados e Conclusão: A queda na cobertura vacinal da poliomielite resulta de diversos fatores, incluindo a hesitação vacinal, o movimento antivacina e desafios relacionados ao Sistema Único de Saúde (SUS) durante a pandemia de COVID-19. É fundamental o investimento no SUS para garantir recursos adequados, capacitação de profissionais e melhoria das instalações de vacinação. Estratégias de comunicação em saúde são essenciais para promover a confiança nas vacinas e combater a hesitação vacinal e movimentos antivacina. A pesquisa teve limitações devido à escassez de publicações sobre o assunto, sugerindo a necessidade de futuras pesquisas com gestores, profissionais e a população para uma compreensão mais abrangente desse fenômeno.
Pengaruh Terapi Relaksasi Otot Progresif Terhadap Nilai Kecemasan Pada Pasien Ca Paru Yang Sedang Menjalani Kemoterapi di RS. Dr. H.A Rotinsulu Kota Bandung
Authors: Rustandi Budi 
Published: November 2023

ABSTRAK
Kemoterapi merupakan salah satu terapi pilihan untuk pasien kanker, tetapi memiliki banyak efek samping yang sering membuat pasien cemas. efek samping dari kecemasan pada pasien kemoterapi adalah agresif, depresi, keletihan, gugup, peningkatan meningkatkan denyut jantung dan tekanan darah, sehingga proses pemberian kemoterapi tidak bisa dilakukan. penelitian ini bertujuan untuk mengidentifikasi pengaruh PMR terhadap kecemasan pada pasien kanker paru yang menjalani kemoterapi di Rumah Sakit Dr. H.A. Rotinsulu Kota Bandung. Dengan desain penelitian adalah quasi eksperimental dengan desain pre and post without control ini melibatkan 42 responden yang menjalani kemoterapi di Ruang Dahlia Rumah Sakit Dr. H.A Rotinsulu. Dengan mengggunakan Tehnik Consecutive sampling. Kuesioner penelitian menggunakan Kuesioner Kecemasan SRAS yang dirancang oleh Wiliam WK Zung. Data dianalisis menggunakan analisis dengan uji Paired t-test. Hasil penelitian menunjukkan bahwa rata-rata skor kecemasan pada pengukuran sebelum diberikan intervensi sebesar 66,97 dengan standar deviasi 3,57 sementara skor kecemasan setelah diberikan intervensi sebesar 47,78 dengan standar deviasi 4,98. Hasil analisis lanjutan menunjukkan bahwa ada perbedaan yang signifikan skor kecemasan sebelum dan setelah diberikan intervensi PMR (p-value < 0,001). Disimpulkan bahwa terdapat pengaruh terapi PMR terhadap penurunan tingkat kecemasan pada pasien kanker paru yang menjalani kemoterapi.

Kata kunci : Kemoterapi, Kecemasan dan PMR
Gambaran Pelaksanaan Pendidikan Kesehatan pada Area Praktik Keperawatan di Wilayah Bandung Raya
Authors: Permana Ryan Hara , Adiningsih Dian 
Published: November 2023

Peningkatan kualitas pendidikan kesehatan di wilayah Bandung Raya berpotensi meningkatkan kualitas hasil perawatan yang berdampak pada peningkatan derajat kesehatan penduduk. Penelitian ini merupakan survey pendahuluan untuk memotret bagaimana pelaksanaan pendidikan kesehatan di area praktik keperawatan di wilayah Bandung Raya. Penelitian ini merupakan penelitian deskriptif kuantitatif dengan desain cross sectional dengan menggunakan metode survey. Data dianalisa dengan analisis distribusi frekuensi dan tendensi sentral. Hasil menunjukkan bahwa media ajar yang paling sering digunakan yaitu leaflet dan media ajar yang banyak dibutuhkan yaitu video dengan rata-rata kualitas media ajar yaitu cukup baik. Metode pendidikan kesehatan yang paling sering dilakukan oleh responden yaitu ceramah dan diskusi. Tempat yang paling banyak digunakan oleh responden untuk melaksanakan pendidikan kesehatan yaitu ruang pasien dengan rata-rata kualitas cukup baik. topik yang paling banyak diajarkan yaitu kategori keperawatan medial bedah. Rerata intensitas pelaksanaan pendidikan kesehatan yaitu kategori sering. Sebagai kesimpulan, gambaran pelaksanaan pendidikan kesehatan dijelaskan dalam pembahasan termasuk terkait media, metode, tempat, intensitas dan topik pembelajaran. Pelaksanaan pendidikan kesehatan perlu disusun secara sistematis dan perlu dilakukan penelitian lebih lanjut dengan instrumen yang sesuai pada masing-masing elemen sistem desain instruksional.
Improving bioenergy recovery from municipal wastewater with a novel cloth-filter anaerobic membrane bioreactor
Authors: Martins-West Neriamara , Martin-Ryals Ana , Maxwell Bryan , Schideman Lance 
Published: November 2023

Anaerobic membrane bioreactors (AnMBR) have been used for treating high-strength industrial wastewater at full-scale and the potential to use them for mainstream municipal wastewater treatment presents an important opportunity to turn energy-intensive plants into net-energy producers. However, several limitations of the AnMBR technology have prevented their adoption in the municipal wastewater industry, namely, high membrane cleaning energy demand and low membrane flux. This study demonstrated a novel AnMBR configuration that uses a commercially available cloth filter technology to address the key limitations of cleaning energy and membrane flux. The cloth filter anaerobic membrane bioreactor (CFAnMBR) is comprised of an anaerobic fixed-film bioreactor coupled with a cloth filter membrane with nominal pore size of 5 µm. The pilot CFAnMBR was operated for 150 days through the winter at a municipal wastewater plant in central Illinois (minimum/average influent temperature 5/13°C). The CFAnMBR increased membrane flux by more than 2 orders of magnitude (3,649 ± 1,246 L per meter squared per hour) and reduced cleaning energy demand by 78%—92% (0.0085 kWh/m3) relative to previously reported AnMBR configurations. With the CFAnMBR, average chemical oxygen demand and total suspended solids removal were 66% and 91%, respectively, and were shown to be increased up to 88% and 96% by in-line coagulant dosing with ferric chloride. Average headspace methane yield was 154 mL CH4/g CODremoved by the end of the study period with influent temperatures of 11°C± 4°C. The CFAnMBR resolves major limitations of AnMBR technology by employing a commercially-available technology already used for other municipal wastewater treatment applications.
Risk factors for immediate and delayed cardiogenic shock in patients with ventricular septal rupture after myocardial infarction
Authors: Wang Si , Zhang Jing , Xiao Qian-Feng , Liu Kai , Xu Ying , Chen Xiao-Ping , Wei Xin , Peng Yong 
Published: November 2023

BackgroundVentricular septal rupture (VSR) is a serious complication occurring after myocardial infarction (MI). Cardiogenic shock (CS) is a common complication of VSR and an important factor affecting its prognosis. CS can occur in either an immediate or delayed manner after VSR; however, studies on the risk factors associated with immediate or delayed CS are scarce.MethodsWe retrospectively studied patients diagnosed with VSR after MI and admitted to the West China Hospital between September 2009 and August 2023. Demographic data, medical history, physical examination results, electrocardiograms, and echocardiographic and hematological data were extracted from electronic medical records or archived records. CS was defined as hypotension (&lt;90 mmHg) and/or the requirement for catecholamines, pulmonary congestion, and signs of end-organ failure. The CS onset time was defined as the time at which catecholamines were initiated.ResultsA total of 88 patients with VSR after MI, including 49 males (55.7%), were enrolled. The average age was 70.2 years. Of these patients, 32 (36.4%) who already had CS at the time of VSR discovery were defined as immediate CS, and 28 (31.8%) who developed CS within 2 weeks after VSR discovery were defined as delayed CS. A smaller left ventricular end-diastolic diameter (LVEDD) and VSR discovered after admission were independent risk factors for immediate CS. Elevated heart rate and higher levels of creatine kinase-MB isoenzyme on admission were independent risk factors for delayed CS in patients without immediate CS after VSR.ConclusionsThe occurrence of CS in patients with VSR after MI has an evident time course. Thus, an early identification of patients at risk of immediate or delayed CS and optimization of treatment procedures may help improve the prognosis.
Association between dynamic change patterns of body mass or fat mass and incident stroke: results from the China Health and Retirement Longitudinal Study (CHARLS)
Authors: Lin Mengpi , Zhou Shanting , Gu Shanhong 
Published: November 2023

ObjectiveTo assess the association between dynamic patterns of change in body mass or fat mass and stroke.MethodsA population-based cohort of participants was selected from the China Health and Retirement Longitudinal Study (CHARLS). Body mass and fat mass were measured using obesity-related indices, including weight, body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), lipid accumulation product (LAP), and visceral adiposity index (VAI). Five changed patterns were defined: low-stable, decreasing, moderate, increasing, and persistent-high. Logistic regression analysis was performed to evaluate the association between obesity-related indices and stroke.ResultsA total of 5,834 participants were included, and the median age was 58.0 years. During a 7-years follow-up period, 354 (6.1%) participants developed stroke. The baseline levels of obesity-related indices were significantly associated with incident stroke. Regarding the dynamic change patterns, the low-stable pattern carried the lowest odds for stroke and the persistent-high pattern had the highest odds for stroke, with odds ratios of all the indices ranging from 1.73 to 3.37 (all P &lt; 0.05). The increasing pattern was also associated with a higher odds of stroke, whereas the moderate pattern of weight, BMI, and WHtR was comparable to the low-stable pattern in terms of stroke.ConclusionCurrent status and dynamic changes in body mass and fat mass were significantly associated with incident stroke. Maintaining the low-stable pattern of body mass and fat mass as measured by weight, WC, BMI, WHtR, LAP, and VAI may be an alternative strategy for primary stroke prevention.
A simplified single transseptal puncture approach using high-density 3D voltage mapping for atrial fibrillation ablation: acute complications and long-term results
Authors: Silva Cunha Pedro , Teixeira Bárbara Lacerda , Laranjo Sérgio , Portugal Guilherme , Valente Bruno , Delgado Ana Sofia , Pereira Mariana , Rocha António Condeixa , Brás Manuel , Cruz Madalena Coutinho , Paulo Margarida , Lousinha Ana , Guerra Cátia , Ferreira Rui Cruz , Oliveira Mário Martins 
Published: November 2023

BackgroundAn ablation catheter and a circular mapping catheter requiring a double transeptal puncture (TSP) for left atrial access have been conventionally used for atrial fibrillation (AF) ablation. Recently, different operators have combined a single transseptal puncture technique with 3D high-density mapping catheters for pulmonary vein isolation (PVI).ObjectiveThis study aims to compare two strategies, single vs. double TSP, regarding the duration of the procedure, radiation time, complication rates, and outcomes.MethodsRetrospective analysis of a large cohort of consecutive patients that underwent first PVI with radiofrequency energy (RF), using a point-by-point strategy, with a 3D mapping system, either with single or double TSP, according to the operator's choice.Results285 patients with a mean age of 59.5 ± 11.6 years (36.5% female, 67.7% paroxysmal AF) underwent a point-by-point catheter ablation with RF between July 2015 and March 2020. The mean CHA2DS2-VASc score was 1.7 ± 1.3. Single TSP was performed in 115 (40.3%) patients and double TSP in 170 (59.6%). The operator's experience (≥5 years of AF ablation procedures) was equally distributed among the two groups. The average procedure time (133 ± 31.7 min vs. 123 ± 35.5 min, for single and double TSP, respectively) did reach a statistical difference between both groups (p = 0.008), but there was a substantial advantage regarding fluoroscopy time (13 ± 6.3 min vs. 19 ± 9.1 min, for single and double TSP, respectively; p &lt; 0.001). Acute major complications present similar rates in both groups (2.6% vs. 2.3%, p = 0.799). At the 2-year follow-up, both groups had a similar sinus rhythm maintenance rate (76.5% vs. 78.8%, p = 0.646).ConclusionA simplified single-TSP technique using high-density multi-electrode 3D mapping is a safe and highly successful option for AF ablation. This approach yields a substantial reduction in fluoroscopy time, with the potential to avoid acute complications, compared to a conventional double-TSP strategy.
Geological controls on the geothermal system and hydrogeochemistry of the deep low-salinity Upper Cretaceous aquifers in the Zharkent (eastern Ily) Basin, south-eastern Kazakhstan
Authors: Kozhagulova Ashirgul , Yapiyev Vadim , Karabayanova Leila , Dillinger Antoine , Zavaley Vyacheslav , Kalitova Aisulu , Bayramov Emil , Holbrook John , Grasby Stephen E. , Fustic Milovan 
Published: November 2023

The Zharkent (eastern Ily) Basin is renowned for its low-salinity natural hot springs and geothermal wells, primarily utilized for recreational purposes. Despite the growing commercial interest, the geothermal system in this area is very poorly documented or understood. Accordingly, we conducted a multi-disciplinary study, focusing on the advanced characterization of waters from productive Cretaceous strata, along with the interpretation of geothermal gradients and reservoir recharge in a geological context. Conventional wisdom asserts that Ily is an intracratonic basin characterized by high geothermal heat in its central part and by geothermal aquifers that are rapidly replenished by meteoric water recharge via porous strata exposed on the basin margin. Our results argue for an alternative and expanded interpretation of these systems. Elevated geothermal gradients (with average of up to 40°C/km in the southern part of the basin and locally possibly up to 55°C/km) are likely associated with crustal thinning owing to the development of a pull-apart basin. Anomalously fresh water (&lt;1 g/L) in the deep (up to 2850 m depth) Upper Cretaceous reservoir is charged laterally, predominantly by snowmelt waters from basin bounding mountains. Recharge includes both mountain-front recharge (MFR), where water infiltrates into outcrops of reservoir rock near the mountain fronts, and mountain-block recharge (MBR), characterized by deep groundwater flow through fractured, predominantly rhyolite basement rocks (as evidenced from their solutes in reservoir waters). The combination of elevated geothermal gradients, low salinity water chemistry, and excellent reservoir properties makes the studied reservoir horizon an attractive target for geothermal development. Our results are applicable to other geothermal systems in strike-slip settings across Central Asia, and potentially worldwide.
Investigation of groundwater potential using gravity data in Wadi Fatimah and its surroundings, Western Saudi Arabia
Authors: Alshehri Fahad , Mohamed Ahmed 
Published: November 2023

Water scarcity is becoming a growing problem in the Middle East due to urbanization, industrialization, and population growth. Saudi Arabia is one of the region’s largest consumers of water, so it is important to take immediate action to address this issue. This study used data from the Gravity Recovery and Climate Experiment (GRACE) to assess changes in groundwater storage in Wadi Fatimah and its surrounding areas. The results showed that the average annual rainfall (AAR) in Wadi Fatimah was 131 mm, while the AAR for the entire Makah province was 99.3 mm. The AAR in Makah province can be divided into three climatic periods: Period I (April 2002-December 2011): AAR of 92.8 mm; Period II (January 2012-December 2016): AAR of 101.8 mm and Period III (January 2017-December 2021): AAR of 116.4 mm. The GRACE-derived ΔTWS (time-variable gravity) variations were −0.18 ± 0.023 cm/yr in Wadi Fatimah and −0.38 ± 0.018 cm/yr in the entire Makah Province. The soil moisture storage (ΔSMS) variations were +0.039 ± 0.025 mm/yr in Wadi Fatimah and −0.008 ± 0.002 mm/yr in the entire Makah Province. The average groundwater storage (ΔGWS) variation in Wadi Fatimah was −0.18 ± 0.022 cm/yr, which indicates a slight decrease. The ΔGWS variation in the entire Makah region was −0.38 ± 0.017 cm/yr, which indicates a negative trend. The study also found that surface runoff from rainfall in the eastern section of Wadi Fatimah flows westward to join other streams that flow into the Wadi’s central and downstream areas. This runoff replenishes the shallow alluvium deposits and aquifers. Wadi Fatimah is able to partially compensate for the impact of its groundwater extraction with a recharge rate of +0.22 ± 0.22 mm/yr. The integrated method used in this study is a helpful and economical way to evaluate groundwater resource variability over Wadi Fatimah region and its surrounding province.
Adaptation of the Parents Taking Action program for Diné (Navajo) parents of children with autism
Authors: Lindly Olivia J. , Running Bear Candi L. , Henderson Davis E. , Lopez Kristina , Nozadi Sara S. , Vining Christine , Bia Shannon , Hill Erin , Leaf Anna 
Published: November 2023

PurposeNeurodivergent children who are part of Indigenous communities in rural areas often have inequitable access to specialized services. Parent education and training programs can be used to help address these gaps in the service system. Yet few parent education and training programs exist for Indigenous parents of children with autism, including parents who identify as Diné (Navajo, meaning “The People”), the largest federated tribe in the United States. The Parents Taking Action (PTA) program is a parent education and training program delivered by community health workers that was originally developed for Latine parents of children with autism. The PTA program has been culturally adapted for other groups, and a growing evidence base exists supporting the program’s feasibility, acceptability, and efficacy. We, therefore, sought to adapt the PTA program for Diné parents.MethodsThis was a community-engaged case study on how the PTA program was adapted for Diné parents of children with autism. A community advisory board (CAB) comprised of 13 individuals including Diné parents of children with autism and professionals helped guide the adaptation process. We interviewed 15 Diné parents of a child with autism about their needs and preferences for the PTA program and used this information to adapt the PTA program. CAB workgroups used the Ecological Validity Framework to provide input on adaptations needed for the original PTA program materials. We also obtained input on the program’s adaptation from Diné communities and a PTA research collaborative.ResultsTo incorporate the CAB’s collective feedback on the PTA program adaptation, we modified terminology, visuals, and narratives. From the parent interview findings, we reduced the number of lessons and enabled community health workers to deliver lessons remotely. We further integrated feedback from the CAB workgroups in the adaptation of specific lessons. We addressed feedback from the larger community by expanding our project’s catchment area and involving additional programs.ConclusionThis case study demonstrates how an evidence-based, parent education and training program was adapted for Diné parents of children with autism. The adapted Diné PTA program is being piloted. We will continue to improve Diné PTA by using the pilot’s results and community input to inform future adaptations.