bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of sacha inchi (Plukenetia volubilis) and taro (Colocasia esculenta) flours with potential application in the preparation of both gluten-free and high protein foods.
Authors: Narváez Cadena Ruby Aracely , Salas Zambrano Angie Paola , Bravo Gómez Jesús Eduardo , Muñoz Pabon Karen Sofia , Roa-Acosta Diego Fernando 
Published: October 2023

Background: Interest in alternative sources of tubers and legumes has increased in recent years because of the constant search for raw materials that provide bioactive compounds with antioxidant potential benefits for consumers. The functionality of new raw materials is sought through physical and/or chemical modifications to develop and innovate new foods. The objective of this study was to characterize taro (TF) (Colocasia esculenta) and sacha inchi (Plukenetia volubilis) flours, obtained by the wet (SIF-WM) and defatted method (SIF-DM), as an alternative for the formulation of new functional foods. Methods: The free polyphenols of the different mixtures were analyzed, and the antioxidant properties of the extracts obtained were measured using ABTS.* (2,2′-Azino-bis(3-ethylbenzthiazoline-6-sulfonic acid). The ABTS radical method, which reacts with the phenolic compounds of the food matrix, using Trolox as a standard. The blends were subjected to pasting analysis, flow profile tests, determination of viscoelastic properties (temperature sweep). Characterization of common microorganisms in these foods was performed. Results: The highest protein value was obtained in the sacha inchi flour obtained by the defatted method (72.62). The majority of components in taro were carbohydrates (85.4%). About antioxidant and determination of free polyphenols, taro flour obtained values of 2.71 µmol ET/g and 7.47 mg EAG/g, higher than Sacha inchi flours. In the rheological analysis (pasting properties, flow profile, and viscoelasticity), we observed that adding taro flour in different mixtures increases the viscosity peak and a lower breakdown, while there was an increase in setback. Except for defatted sacha flour, the others presented a flow index >1 before heating, showing a dilatant fluid behavior. The presence of Taro flour improves gel formation and stability. Staphylococcus aureus and Salmonella were present in the taro flour. Conclusions: The flours analyzed represent a raw material with great potential for the development of gluten-free foods with functional properties.
Economic effects of the war in Ukraine and recession
Authors: korriku belisa , TARTARAJ AZETA 
Published: October 2023

Background: The current situation from economic effects of war, as political uncertainty, geographic proximity,and the impact of new sanctions against Russia,has led to negative reactions in European stock markets.Previous research has shown that economic crises can have significant impacts on consumer financial behaviors and attitudes. Methods:The purpose of the study was to examine how consumer attitudes and behaviors change during periods of recession and to identify the implications for financial education and management during challenging economic times.Demographic data and financial management behavior data were collected from a sample 428 respondents.By examining consumer attitudes and behaviors during a recession,this study can provide insights into how financial education and management can be improved to support consumers during challenging economic times.A survey was conducted to investigate the financial attitudes and behaviors of individuals during a recessionary period from January 15th to February 28th,2023 and included questions about age, financial education level,savings behavior,attitudes towards debt,gender and financial management behavior,age and financial education, and income and savings behavior.Data were analyzed using t-tests and ANOVA. Results:Participants with higher income levels had higher levels of savings and investing behaviors than those with lower income levels. Participants with a higher level of formal education in finance had higher levels of budgeting and investing behaviors than those with a lower level of formal education in finance. Participants who reported higher levels of self-rated financial knowledge had higher levels of all financial management behaviors compared to those with lower self-rated financial knowledge. Conclusions:The findings suggest that financial education and management programs should target individuals with lower income levels and less formal education in finance. Promoting self-rated financial knowledge may be a useful strategy for improving financial management behaviors. Future research could explore the effectiveness of different financial education and management programs on improving financial attitudes and behaviors during recessionary periods.
Effect of enzymatic maceration and homogenization by shear on the stability of pumpkin suspension (Cucúrbita maxima) incorporating its vegetable co-products (peel and seed)
Authors: Caballero Gutiérrez Birina Luz , Márquez Cardozo Carlos Julio , Ciro Velázquez Héctor José , Cortés Rodríguez Misael 
Published: October 2023

Background: Pumpkin fruits have worldwide agro-industrial importance and are rich in carotenoids, vitamins, and minerals. However, during processing, their peels and seeds, which have a high nutrient content, are generally discarded as solid waste. This work aimed to evaluate the influence of the processes of enzymatic maceration and homogenization by shear on the stability of a suspension of the pumpkin (pulp+seed+peel). Methods: A centralized composite design was used considering the enzyme dose (X1) with filter paper units (FPU) (21, 31, 42/g dry basis (db)) of substrate, hydrolysis time (X2) (2, 3.5, 5 h), and homogenization time (X3) (5.0, 7.5, 10.0 min), and the following variables were measured: zeta potential (ζ), particle size, apparent viscosity (µ), spectral absorption R index, total carotenoid, and antioxidant capacity by DPPH⸳ (2,2-diphenyl -1-picrylhidrazyl radical) and ABTS•+ (2,2´-azinobis- (3-ethylbenzothiazoline-6-sulphonate). A theoretical optimization and experimental validation were performed using the desirability approach with multiple responses. Results: The optimization had a desirability function (79.9%), X1: 42 FPU/g db, X2: 4.68 h, and X3: 8.54 min. The ζ and the antioxidant capacity by ABTS•+ were not affected by the independent variables, nor by their interactions. Particle size D [4;3], R index, and antioxidant capacity by DPPH⸳ were mainly affected by X3, while D [3;2], and total carotenoid content were significantly affected by the interaction of X1 and X2. The optimal suspension achieved µ: 369.5 ±59.8 mPa.s, ζ: -28.2±0.6 mV, D[3;2]: 51.18±2.2 μm, D[4;3]: 333±17.4 μm, R Index: 0.43±0.02, total carotenoid: 127.9±9.3 mg/100g db, and antioxidant capacity (DPPH⸳:1083.9±23.9 and ABTS•+: 1485.1±27.1 µmol Trolox Eq/ 100g db). Conclusions: The process of enzymatic maceration and homogenization by shear made it possible to obtain an integral suspension of pumpkin with physicochemical stability and functional attributes, promoting a product with optimal conditions for its potential use in technological applications such as spray drying.
An assessment of the factors contributing to the unavailability of drugs at outpatient pharmacy of tertiary care hospital: an observational study
Authors: Bakare Abhishek , Bhargav Aditya 
Published: October 2023

Introduction Throughout history and up until the present, there has been a medicine shortage. In the early 1920s, there was a shortage of insulin, which is when drug scarcity first appeared in the records. Drug shortages are now more prevalent globally than they were back then. The goal of this essay is to pinpoint the key components that make up a definition for medication shortages and to pinpoint the circumstances that should be considered when reporting drug shortages in databases. Understanding the factors that led certain organizations to create their own definition of a medicine shortage was crucial for achieving these goals. The pharmaceutical regulatory environment can be connected to several reasons why there are medication shortages, including parallel trading, quality standards, and business choices to halt or reduce manufacturing. The many rules governing medicine shortages have not yet been the subject of a thorough investigation. This protocol’s objective is to analyze the pertinent legislative and regulatory frameworks in the European pharmaceutical system that affect medication shortages. The objectives of the study will be the non–availability of drugs at an outpatient pharmacy and to analyze the reason of non–availability of drugs. Methods An observational study will be adopted in this study. It includes a collection of data from the patient coming to the outpatient pharmacy of AVBRH Sawangi (Meghe) Wardha. Expected result It can lead to delayed treatment for patients seeking alternative medication. It can also lead to increased healthcare costs if patients seek alternative treatments that are more expensive or require additional medical care. The unavailability of drugs can also lead to frustration and anxiety for patients who need medication to manage their health condition. It can also negatively impact the reputation of the hospital.
Identification of high-performing antibodies for tyrosine-protein kinase SYK for use in Western Blot, immunoprecipitation and immunofluorescence
Authors: Alshafie Walaa , Fotouhi Maryam , Ayoubi Riham , Southern Kathleen , Laflamme Carl ,   NeuroSGC/YCharOS collaborative group
Published: October 2023

Tyrosine-protein kinase SYK, encoded by the SYK gene, is a non-receptor type protein kinase which mediates immune signal transduction through immunoreceptors. Tyrosine-protein kinase SYK expression has been associated with the development of various inflammatory diseases, cancer and neurodegenerative conditions. The reproducibility of tyrosine-protein kinase SYK research would help elucidate the mechanism in which it causes neuroinflammation as well as its potential as a novel target to treat Alzheimer’s disease. This would be facilitated with the availability of high-quality tyrosine-protein kinase SYK. In this study, we characterized thirteen tyrosine-protein kinase SYK commercial antibodies for Western Blot, immunoprecipitation, and immunofluorescence using a standardized experimental protocol based on comparing read-outs in knockout cell lines and isogenic parental controls. We identified many high-performing antibodies and encourage readers to use this report as a guide to select the most appropriate antibody for their specific needs.
Case Report: Maternal death due to frontal lobe meningioma mimicking postpartum depression
Authors: Lema Alemayehu Shiferaw , Aklilu Emiru Tilahun 
Published: October 2023

Meningiomas are among the most frequent primary brain tumors. Meningiomas can present with psychiatric manifestations such as depression in the absence of any neurological signs and symptoms. This case illustrates a rare and fatal complication of frontal lobe meningioma that finally mimicked postpartum depression in a woman who relied on non-professional sources of help and died without proper diagnosis and treatment. The case reported here highlights the significance of considering frontal lobe meningioma as a possible cause of psychiatric symptoms in postpartum women and recommends performing a thorough neurological examination and neuroimaging if necessary. Clinicians should be aware of this possibility and perform neuroimaging studies in patients with postpartum depression who have atypical features such as persistent headaches. Overall, this paper emphasizes the significance of early diagnosis and intervention of frontal lobe meningiomas to improve patient outcomes and prevent fatal complications.
UMA CARACTERIZAÇÃO DO CONHECIMENTO ESPECIALIZADO DO PROFESSOR DE MATEMÁTICA DA EDUCAÇÃO INFANTIL E ANOS INICIAIS EM TÓPICOS DE MEDIDA
Authors: Policastro Milena , Ribeiro Miguel 
Published: October 2023

En este estudio consideramos las dimensiones matemáticas y pedagógicas del conocimiento del profesor como especializadas, con el objetivo de caracterizar el contenido de este conocimiento, específicamente asociado a los temas de Medidas. Empleando el marco del Mathematics Teacher’s Specialised Knowledge (MTSK), exploramos y describimos el contenido del conocimiento especializado revelado por un grupo de profesores de Educación Primaria en el Brasil mientras abordan una tarea para la formación, en un curso de desarrollo profesional. Los resultados aportan un refinamiento de la categorización del conocimiento docente asociado a los temas (KoT), considerando por separado el detalle del contenido de este conocimento relativo a definiciones, propiedades y fundamentos. Además, el estudio presenta un conjunto de descriptores de conocimiento que resaltan las particularidades y especificidades de este componente del conocimiento docente relacionado con los temas de Medida, permitiendo una especie de mapeo de los elementos estructurales y estructurantes de este conocimiento.
Assessing swallowing disorders in adults on high-flow nasal cannula in critical and non-critical care settings. A scoping review protocol
Authors: Gutierrez-Arias Ruvistay , Salgado-Maldonado Gabriel , Valdivia Paola Letelier , Salinas-Barahona Francisco , Echeverría-Valdebenito Carmen , Seron Pamela ,   on behalf of INTRehab Research Group
Published: October 2023

Introduction
The high-flow nasal cannula (HFNC) has become a widely used respiratory support system, which has proven to be effective in different populations. The facilitation of oral communication and feeding have been described as advantages of this support. Nevertheless, swallowing disorders associated with the use of HFNC have been postulated. However, such evidence is scattered in the literature, not systematically searched, and needs to be adequately summarised. This review aimed to explore the literature, to identify and map the evidence, regarding the frequency and methods of assessment of swallowing disorders in adult HFNC users, in both critical and non-critical units.

Materials and methods
A scoping review will be conducted. A systematic search in MEDLINE (Ovid), Embase (Ovid), CENTRAL, CINAHL (EBSCOhost), and other resources will be conducted. Primary studies, in any language or publication status, assessing the incidence of swallowing disorders in adults with HFNC support will be included. Two reviewers will independently select studies and extract data. Disagreements will be resolved by consensus or a third reviewer. The results will be reported narratively, using tables and figures to support them.

Discussion
Positive end-expiratory pressure generated in the airway by HFNC could impair the proper swallowing performance. Knowing the methodological characteristics, the instruments or scales used to assess the presence of dysphagia, and the results of the studies may contribute to considering swallowing assessment in this population on a routine basis, as well as to guide the conduct of new studies that may respond to less researched areas in this topic.

Registration
Registration number: INPLASY2022110078.
Effectiveness and Safety of Antiobesity Medications in Patients With Obesity and Inflammatory Bowel Disease
Authors: Pham Jonathan T. , Ghusn Wissam , Acosta Andres , Loftus Edward V. , Johnson Amanda M. 
Published: October 2023

INTRODUCTION:
Limited data exist evaluating antiobesity medications (AOM) in patients with inflammatory bowel disease (IBD).

METHODS:
We performed a case-control study evaluating the effectiveness and safety of AOM in patients with IBD with obesity, matched to non-IBD controls.

RESULTS:
After 12 months, the case (n = 36) and control (n = 36) groups achieved similar percent total body weight loss of −6.9 ± 8.3 and −8.1 ± 7.0 (P = 0.30), respectively. Side effect profiles were similar between groups. Seven patients experienced an IBD flare, all managed medically.

DISCUSSION:
AOM use in patients with IBD demonstrated similar effectiveness and safety when compared with that observed in the non-IBD population.
How teaching modality affects Foreign Language Enjoyment: a comparison of in-person and online English as a Foreign Language classes
Authors: Resnik Pia , Dewaele Jean-Marc , Knechtelsdorfer Eva 
Published: October 2023

Abstract
The sudden shift to online foreign language (FL) learning due to the pandemic offered researchers the unique possibility to explore the role of learner emotions in different teaching modalities. This mixed methods paper investigates differences in 437 English as a foreign language (EFL) students’ levels of FL enjoyment (FLE) in pre-pandemic in-person EFL classes and their online classes after the switch to emergency remote teaching (ERT) based on a convergent research design. Statistical analysis of quantitative data gathered with a web survey showed a significant drop in learners’ FLE in ERT, based on a 9-item scale. The sharpest drop was observed for the scales’ subdimensions Personal and Social Enjoyment while Teacher appreciation decreased less. Qualitative content analysis of 21 in-depth interviews revealed that enjoyable aspects were mentioned more frequently for ERT than for in-person classes. The nature of FLE was found to shift with teaching modality: FLE was linked to rich social interactions in in-person classes, while it was linked to the convenience and comfort of working from home and an increase in learner autonomy in ERT. Additionally, learners reported that despite the physical isolation, they managed to establish good social connections in ERT classes. This shows that FLE can flourish in challenging circumstances. Its intensity might differ from in-person classes but it feeds generally on similar nutrients, namely interesting learning materials, friendly and professional teachers and stimulating interactions with peers in order to develop social bonds.
The effect of AQP4 on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts
Authors: Fan Yong , Yang Yongkai , Lin Kunzhe , Zhou Xiaohui , Li Yongkun , Lin Qingqiang 
Published: October 2023

Abstract
This study aimed to investigate the effect of aquaporin-4 (AQP4) on tau protein aggregation in neurodegeneration and persistent neuroinflammation after cerebral microinfarcts. A model of diffuse ischemic brain injury was established, and adenovirus was injected stereotactically through the lateral ventricle of mice. The water content of the brain tissue was measured. The co-expression of glial fibrillary acidic protein (GFAP) and AQP4 and the aggregation of p-tau and neuronal marker were detected through immunofluorescence double staining. The expression of phosphorylated microtubule-associated protein tau (p-tau, Ser202/Thr205, Thr205, Ser396, Ser404), interleukin(IL)-6, IL-1β, tumor necrosis factor (TNF)-a, growth associated protein43 (GAP43), GFAP, and ionized calcium-binding adapter molecule 1 (Iba1) was detected through Western blot. It was found that the brain water content in the model group was increased and decreased after the AQP4 interference. Compared with the sham group, the expression of GFAP, p-tau, IL-1β, TNF-a, Iba1, and p-tau was increased in the model group (p < 0.05). Compared with the model group, the expression of p-tau, IL-6, IL-1β, TNF-a, GFAP, and Iba1 was decreased after AQP4 interference (p < 0.05). It is indicated that AQP4 positively regulates neurodegeneration and persistent neuroinflammation caused by tau protein aggregation after cerebral microinfarcts.
Study of Oscillation Criteria of Odd-Order Differential Equations with Mixed Neutral Terms
Authors: Grace Said R. , Abbas Syed , Negi Shekhar Singh 
Published: October 2023

ABSTRACT
This paper is concerned with the oscillation criteria of odd-order non-linear differential equations with mixed non-linear neutral terms. We provide new oscillation criteria that improve, expand, and simplify existing ones. Moreover, some examples are provided to demonstrate the theoretical findings.
Crystal structure of ethyl 2-((2,6-dichloro-4-(cyanomethyl)phenyl) amino)benzoate, C17H14Cl2N2O2
Authors: Zhao Meimei , Du Mo , Liu Bin 
Published: October 2023

Abstract
C17H14Cl2N2O2, monoclinic, P21/n (no. 14), a = 8.4863(17) Å, b = 12.654(2) Å, c = 15.088(3) Å, β = 103.612(5)°, V = 1574.8(5) Å3, Z = 4, Rgt
(F) = 0.0423, wRref
(F
2) = 0.1472, T = 205 K.
Crystal structure of bis{N′-[1,3-diphenylprop-2-en-1-ylidene]-N-phenylcarbamohydrazonothioato}zinc(II), C44H36N6S2Zn
Authors: Tan Ming Yueh , Crouse Karen A. , Tan Sang Loon , Tiekink Edward R. T. 
Published: October 2023

Abstract
C44H36N6S2Zn, monoclinic, P21/c (no. 14), a = 14.5676(4) Å, b = 26.1767(8) Å, c = 10.0963(3) Å, β = 99.140(3)°, V = 3801.2(2) Å3, Z = 4, Rgt
(F) = 0.0397, wRref
(F
2) = 0.1000, T = 100 K.
Crystal structure of (3-hydroxy-4-methoxyphenyl)(pyrrolidin-1-yl)methanone, C12H15NO3
Authors: Xu Xiaona , Tong Hongjuan , Zhu Zhoujing , Liu Bin 
Published: October 2023

Abstract
C12H15NO3, monoclinic, P21/c (no. 14), a = 6.7230(2) Å, b = 11.1182(3) Å, c = 14.4996(5) Å, β =

94.8870

(
10
)

°

$94.8870(10){}^{\circ}$

, V = 1079.87(6) Å3, Z = 4, Rgt
(F) = 0.0511, wRref
(

F
2

${F}^{2}$

) = 0.1525, T = 170 K.
The crystal structure of bis(trimethylsulfoxonium) catena-poly[µ2-hexabromido-indium(III)sodium(I)] C6H18O2S2NaInBr6
Authors: Jin Shifeng , Lu Jiali 
Published: October 2023

Abstract
C6H18O2S2NaInBr6, orthorhombic, Pmn21 (no. 31), a = 10.5451(3) Å, b = 7.1169(2) Å, c = 13.7034(4) Å, V = 1028.42(5) Å3, Z = 2, Rgt
(F) = 0.0354, wRref
(F
2) = 0.0923, T = 293 K.
Risk analysis of bridge ship collision based on AIS data model and nonlinear finite element
Authors: Zhao Canglong , Cao Xiang , Ren Yunye 
Published: October 2023

Abstract
To solve the problem of calculating the probability of ship collision in ship bridge collision risk assessment, the impact parameters of ship collision are obtained based on the automatic identification system (AIS) data to solve the problem that the existing methods do not consider the actual navigable ship information in a specific bridge navigation area. Based on AIS data, the dynamics of sailing ships are analyzed, parameters such as ship position, speed, and yaw angle, are obtained, ship traffic flow is analyzed, and the geometric probability in the actual ship traffic flow specification model is modified. The results before and after correction were compared and analyzed. The results show that the maximum transverse displacement of the anti-collision device is about 1.5 s under all working conditions, indicating that the collision force drops continuously from this moment to 0 in the collision force time history. In the process of collision, the anti-collision device absorbs part of the collision energy through its own deformation. Under the premise of a certain initial kinetic energy, the deformation caused by the collision energy absorption after fortification will be reduced. The anti-collision device has local permanent deformation under the impact of 5,000 t ship, but no damage and failure, and will not cause water entry and subsidence. It proves that the constructed fishery ship collision risk assessment model and the developed fishery ship safety management and evaluation system are reliable and the prediction results are credible, which can provide scientific methods for the safety management and evaluation of fishery vessels. For the bridge area with complicated ship navigation conditions, it is necessary to use the actual navigable ship information obtained based on AIS data to estimate the distribution of ships in the bridge area to improve the accuracy of the calculation results.