bluuebunny/crossref_metadata_2025_split huggingface dataset:
Determinants of inappropriate complementary feeding among children 6–23 months of age in Dessie City Northeast Ethiopia: a case-control study
Authors: Tadesse Meron , Ali Dawed Yeshimebet , Fentaw Zinabu , Endawike Abel , Adamu Kidist 
Published: November 2023

Abstract
Background
Inappropriate complementary feeding is one of the leading causes of malnutrition among children 6–23 months old and delays children’s growth milestone. The determinants of inappropriate complementary feeding practice have diverse natures, so that many of the previous studies fail to generate adequate evidence on it. This study aim to address the determinants of in appropriate complementary feedings at community level.

Methods
A community-based unmatched case-control study design was carried out among children 6–23 months of age in Dessie City from April 13, 2021 to May 13, 2021. Nine kebeles were selected by simple random sampling method. One month prior to the data collection time survey was conducted and 482 samples were taken from the preliminary survey data; 241 cases and 241 controls by computer generated random numbers. Interviewer administered questionnaire was used to investigate potential determinants of inappropriate complementary feeding practice. Binary logistics regression was used to identify independent determinants.

Results
Part working situation of mother [AOR = 0.21 CI: 0.08, 0.52] was negatively associated with inappropriate complementary feeding. Having no post-natal care visit [AOR = 4.062 CI:2.35,7.02], poor wealth status [AOR = 2.7 CI:1.09,6.68], food in-security [AOR = 4.49 CI:1.94,10.37], home delivery [AOR = 4.33 CI:1.43,13.15], having poor knowledge on infant and young child feeding [AOR = 5.94 CI:2.8,12.6], having no health education on complementary feeding [AOR = 2.54 CI:1.28,5.06] and father’s job [AOR = 2.2 CI:1.17,4.1] were found to be positively associated with inappropriate complementary feeding.

Conclusion
Mothers’ work situation, fathers’ job, wealth index, food security, mothers’ knowledge on infant feeding, post-natal care, health education on infant feeding and place of delivery were independent determinants for inappropriate complementary feeding. Thus, interventions shall effectively address those factors to alleviate the problem.
Weakly-supervised structural surface crack detection algorithm based on class activation map and superpixel segmentation
Authors: Liu Chao , Xu Boqiang 
Published: November 2023

AbstractThis paper proposes a weakly-supervised structural surface crack detection algorithm that can detect the crack area in an image with low data labeling cost. The algorithm consists of a convolutional neural networks Vgg16-Crack for classification, an improved and optimized class activation map (CAM) algorithm for accurately reflecting the position and distribution of cracks in the image, and a method that combines superpixel segmentation algorithm simple linear iterative clustering (SLIC) with CAM for more accurate semantic segmentation of cracks. In addition, this paper uses Bayesian optimization algorithm to obtain the optimal parameter combination that maximizes the performance of the model. The test results show that the algorithm only requires image-level labeling, which can effectively reduce the labor and material consumption brought by pixel-level labeling while ensuring accuracy.
The antiproliferative effect of FGF2 in K-Ras-driven tumor cells involves modulation of rRNA and the nucleolus
Authors: de Luna Vitorino Francisca N. , Levy Michaella J. , Mansano Wailemann Rosangela A. , Lopes Mariana , Silva Mariana Loterio , Sardiu Mihaela E. , Garcia Benjamin A. , Machado Motta Maria Cristina , Oliveira Carla Columbano , Armelin Hugo Aguirre , Florens Laurence A. , Washburn Michael P. , Pinheiro Chagas da Cunha Julia 
Published: November 2023

ABSTRACT
The nucleolus is sensitive to stress and can orchestrate a chain of cellular events in response to stress signals. Despite being a growth factor, FGF2 has antiproliferative and tumor-suppressive functions in some cellular contexts. In this work, we investigated how the antiproliferative effect of FGF2 modulates chromatin-, nucleolus- and rDNA-associated proteins. The chromatin and nucleolar proteome indicated that FGF2 stimulation modulates proteins related to transcription, rRNA expression and chromatin-remodeling proteins. The global transcriptional rate and nucleolus area increased along with nucleolar disorganization upon 24 h of FGF2 stimulation. FGF2 stimulation induced immature rRNA accumulation by increasing rRNA transcription. The rDNA-associated protein analysis reinforced that FGF2 stimulus interferes with transcription and rRNA processing. RNA Pol I inhibition partially reversed the growth arrest induced by FGF2, indicating that changes in rRNA expression might be crucial for triggering the antiproliferative effect. Taken together, we demonstrate that the antiproliferative FGF2 stimulus triggers significant transcriptional changes and modulates the main cell transcription site, the nucleolus.
Seasonal energetics: are insects constrained by energy during dormancy?
Authors: Roberts Kevin T. , Szejner-Sigal Andre , Lehmann Philipp 
Published: November 2023

ABSTRACT
In seasonal environments, many animals, including insects, enter dormancy, where they are limited to a fixed energy budget. The inability to replenish energetic stores during these periods suggests insects should be constrained by pre-dormancy energy stores. Over the last century, the community of researchers working on survival during dormancy has operated under the strong assumption that energy limitation is a key fitness trait driving the evolution of seasonal strategies. That is, energy use has to be minimized during dormancy because insects otherwise run out of energy and die during dormancy, or are left with too little energy to complete development, reproductive maturation or other costly post-dormancy processes such as dispersal or nest building. But if energy is so strongly constrained during dormancy, how can some insects – even within the same species and population – be dormant in very warm environments or show prolonged dormancy for many successive years? In this Commentary, we discuss major assumptions regarding dormancy energetics and outline cases where insects appear to align with our assumptions and where they do not. We then highlight several research directions that could help link organismal energy use with landscape-level changes. Overall, the optimal energetic strategy during dormancy might not be to simply minimize metabolic rate, but instead to maintain a level that matches the demands of the specific life-history strategy. Given the influence of temperature on energy use rates of insects in winter, understanding dormancy energetic strategies is critical in order to determine the potential impacts of climate change on insects in seasonal environments.
The distress context of social calls evokes a fear response in the bat Pipistrellus abramus
Authors: Yoshino-Hashizawa Kazuki , Nishiuchi Yuna , Hiragochi Midori , Kihara Motoki , Kobayasi Kohta I. , Hiryu Shizuko 
Published: November 2023

ABSTRACT
Bats primarily use sound information, including echolocation, for social communication. Bats under stressful conditions, for example when confronted by a predator, will emit aggressive social calls. The presentation of aggressive social calls, including distress calls (DCs), is known to increase heart rate (fH), but how this change in fH is related to the bat's sound perception and how this evokes behaviors such as the fear response is unknown. Herein, we show that the perception of a distress context induces freezing behavior as a fear response in bats. We found that bats responded by freezing and displayed increased fH when they were presented with a conspecific donor bat in a distress situation evoked by gentle poking with a cotton swab. In addition, when we presented two types of auditory oddball paradigms with different probabilities of DCs and echolocation calls (ECs), the bats' fH increased when DCs were presented as deviant or control stimuli within standard ECs but did not increase when DCs were presented as standard stimuli. These results suggest that the situational context created by the frequency of sound presentation, rather than simply a single sound feature, induces fH increases and freezing as fear responses in bats.
The Company She Seeks: How the Prismatic Effects of Ties to High-Status Network Contacts Can Reduce Status for Women in Groups
Authors: Yu Siyu , Shea Catherine 
Published: November 2023

Women experience chronically inferior returns in organizations. One common recommendation is to form instrumental network ties with high-status others in groups. We integrate research on social status, social perceptions, and gender issues in social networks to suggest that, despite the theoretical and empirical appeal of this approach, instrumental ties to high-status network contacts (versus ties to lower-status network contacts) in groups may incur hidden social status costs for women in intragroup status-conferral processes. Instrumental ties to high-status network contacts may be perceived as a sign of agency of the focal person, which violates feminine gender norms. Women with these high-status network contacts in groups may therefore be perceived as less communal, thus subsequently lowering their status in the eyes of other group members compared with women with lower-status network contacts. Studies 1–4, across cross-sectional, longitudinal, and experimental designs, support our model. Study 5 suggests that signaling a group-oriented goal may mitigate the interpersonal, social perceptual costs of instrumental ties to high-status network contacts for women. The effect of ties with high-status network contacts for men is relatively inconsistent. This research reveals a potential social-network dilemma for women: Instrumental ties to high-status network contacts in groups and organizations are necessary for success and should be encouraged, yet they may also create an extra social perceptual hurdle for women. Organizations need to investigate social and structural solutions that harness the benefits of high-status network contacts for women, while minimizing any potential social perceptual costs. Funding: Financial support from the Jones Graduate School of Business, Rice University, is gratefully acknowledged. Supplemental Material: The online appendix and data files are available at https://doi.org/10.1287/orsc.2020.14640 .
Colonic mucosal associated invariant T cells in Crohn’s disease have a diverse and non-public T cell receptor beta chain repertoire
Authors: Konecny Andrew J. , Shows Donna M. , Lord James D. 
Published: November 2023

Objectives
Mucosal-Associated Invariant T (MAIT) cells are T cells with a semi-invariant T cell receptor (TCR), recognizing riboflavin precursors presented by a non-polymorphic MR1 molecule. As these precursors are produced by the gut microbiome, we characterized the frequency, phenotype and clonality of MAIT cells in human colons with and without Crohn’s disease (CD).

Methods
The transcriptome of MAIT cells sorted from blood and intestinal lamina propria cells from colectomy recipients were compared with other CD8+ T cells. Colon biopsies from an additional ten CD patients and ten healthy controls (HC) were analyzed by flow cytometry. TCR genes were sequenced from individual MAIT cells from these biopsies and compared with those of MAIT cells from autologous blood.

Results
MAIT cells in the blood and colon showed a transcriptome distinct from other CD8 T cells, with more expression of the IL-23 receptor. MAIT cells were enriched in the colons of CD patients, with less NKG2D in inflamed versus uninflamed segments. Regardless of disease, most MAIT cells expressed integrin α4β7 in the colon but not in the blood, where they were enriched for α4β7 expression. TCR sequencing revealed heterogeneity in the colon and blood, with few public sequences associated with cohorts.

Conclusion
MAIT cells are enriched in the colons of CD patients and disproportionately express molecules (IL-23R, integrin α4β7) targeted by CD therapeutics, to suggest a pathogenic role for them in CD. Public TCR sequences were neither common nor sufficiently restricted to a cohort to suggest protective or pathogenic antigen-specificities.
Maternal folic acid supplementation and the risk of ankyloglossia (tongue-tie) in infants; a systematic review
Authors: Rubin Gal , Stewart Catherine , McGowan Laura , Woodside Jayne V. , Barrett Geraldine , Godfrey Keith M. , Hall Jennifer 
Published: November 2023

Background
Maternal folic acid supplementation is protective against the development of neural tube defects (NTDs) in babies. However, recent public-facing communications have raised concerns about a causal relationship between folic acid supplementation, particularly after the first trimester, and ankyloglossia (tongue-tie) in infants. Non-evidence-based communications are potentially harmful because they could adversely affect adherence to folic acid supplementation, increasing NTD occurrence. This study aimed to review evidence on the relationships between maternal folic acid supplementation during preconception and/or pregnancy and the risk of ankyloglossia in infants.

Methods
We searched the databases MEDLINE, EMBASE, Cochrane CENTRAL, and Scopus. We searched for observational, and interventional studies, and systematic reviews investigating the effect of maternal folic acid supplementation during preconception or pregnancy on the occurrence of ankyloglossia in offspring. The search was registered on PROSPERO on 01/12/2022, ID: CRD42022375862.

Results
The database searches yielded 93 articles. After removing duplicates and screening titles and abstracts, 26 remained. One article was judged relevant for inclusion in analyses; a case-control study that directly mentions the relationship between folic acid supplementation and ankyloglossia. This study reported that regular intake of folic acid supplements was higher in women with infants with ankyloglossia. However, this study has limitations regarding design, selection bias, and confounding, calling the findings into question.

Conclusions
Insufficient evidence exists for a relationship between folic acid supplementation and ankyloglossia. Currently, the benefits of folic acid supplementation far outweigh the risks. This must be clearly communicated to patients by their clinicians during preconception and antenatal care.
Utilizing Spectral Indices to Estimate Total Dissolved Solids in Water Body Northwest Arabian Gulf
Authors: Al-Fartusi Adel Jassim , Malik Mutasim Ibrahim , Abduljabbar Hameed Majeed 
Published: November 2023

Remote sensing techniques have made it possible to monitor an important parameter of water quality, total dissolved solids (TDS), more appropriately and regularly. The research aims to assess Landsat 8 OLI images' ability to expose TDS on the sea surface in Iraqi marine waters. six band combinations were employed in the correlation analysis between band values and six dissolved solids samples collected during the fieldwork in three sampling stations to determine the amount of total dissolved solids (TDS): st1, st2, and st3 in December 2014 (26,38,36.9) g.L-1 and mid-January 2022 (27.4,37.9,37) g.L-1, respectively. Furthermore, two images of the Landsat-8 OLI satellite were captured concurrently with the gathering of samples for TDS detection at the measuring stations. After atmospheric correction and the add the remote sensing indicators, the reflectance of water was extracted from satellite images and utilized to express the spectral characteristics of various TDS concentrations, since the values were (22.64, 38, 32.46) g.L-1 in 2014, and (27.5, 36.68, 38) g.L-1 in 2022. Correlation coefficient (R2) values of 0.81, 0.96, and Pearson correlation (r) values of 0.90, 0.97 were found among field measurements and spectral data of TDS indicator 2 (SI-2) derived from green, blue, and red bands of Landsat -8 at 2014, 2022 respectively.
External Disruption and Creativity: When the West Looked Up to the East
Authors: Sgourev Stoyan V. 
Published: November 2023

Abstract
A key objective in explaining how creativity occurs and novelty is generated [may it be organized or not], is allowing for a mix of determinism and chance. One of the ways to create a disconnect between the creative act and the myriad factors bearing on it is by way of external jolts, disrupting not only routines and logics, but also structures of attention. The paper highlights the role of external disruption in novelty generation, and articulates a moderating mechanism of perceptual nature by drawing on the work of Foucault. As illustration, I discuss the “externalization” of artistic attention and the construction of counter-sites in late 19th century Western Europe by appropriating Japanese art to conceive of alternatives to academic art. I suggest that external disruptions are most consequential when they reinforce internal relational schisms.
Introduction: the limits of the explanatory potential of the alienability contrast
Authors: Rose Françoise , Van linden An 
Published: November 2023

Abstract
This introductory article outlines the central topic of the present special issue, viz. the contrast between alienable and inalienable possession, and how this contrast is reflected in the grammars and lexicons of natural languages. It sketches the historical background of the alienability contrast in the linguistic literature and points to a number of biases that need to be overcome in order to (1) advance our understanding of the contrast and (2) face the limits of its explanatory potential. Specifically, the present introduction, as well as the contributions to the present issue, proposes to move beyond prototypical possessive relationships (ownership, part-whole, and kinship relations), prototypical possessor categories (human possessors) as well as prototypical possessee categories (artifacts, body-parts and kin). In addition, the issue contains three contributions dealing with Amazonian languages, thus filling in an important gap in previous crosslinguistic studies on possession. The data presented in the special issue show that many morphosyntactic phenomena that have been explained in terms of the alienability contrast – or are amenable to such explanations – cannot be reduced to it, and are sometimes even better described without recourse to alienability at all. The present article thus concludes that the alienability contrast is at best regarded as a heuristic tool in exploring linguistic data, and cautions that, if used as the only explanatory principle, it could actually hamper an adequate description of the data.
Exosomal circular RNA NT5E driven by heterogeneous nuclear ribonucleoprotein A1 induces temozolomide resistance by targeting microRNA-153 in glioma cells
Authors: Wang Renjie , Jia Ruichao , Dong Junqiang , Li Nan , Liang Haiqian 
Published: November 2023

Abstract

Objectives
Exosomally transferred circular RNAs (circRNAs) are critical in cancer. However, the study of exosomal circRNAs in glioma resistance remains limited. Here, we further investigated the function and mechanism of exosomal circular RNA NT5E (circNT5E) in temozolomide-resistant glioma cells (TMZ-GCs).

Methods
Exosomes were isolated from TMZ-GCs and identified by transmission electron microscopy (TEM), nanoparticle tracking analysis (NTA), and Western blotting. CircNT5E, microRNA-153 (miR-153), and heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) levels were measured by quantitative reverse transcription-polymerase chain reaction (qRT-PCR) in TMZ-sensitive and TMZ-resistant GCs and in treated TMZ-GCs. In addition, the colocalization of circNT5E and miR-153 was confirmed by fluorescence in situ hybridization (FISH) and dual-luciferase reporter assays. Internalization of exosomes was observed by immunofluorescence staining. TMZ resistance, proliferation, and pAKTser473 protein levels were evaluated by a Cell Counting Kit-8 (CCK-8) assay, an EdU incorporation assay, and Western blotting, respectively. In addition, tumor growth was examined using a xenograft tumor model in nude mice.

Results
We first proved that circNT5E was highly abundant in exosomes derived from TMZ-GCs. Then, we discovered that circNT5E could serve as a miR-153 sponge. Finally, knockdown of circNT5E reduced TMZ resistance and cell proliferation and downregulated AKTser473 phosphorylation by targeting miR-153 in TMZ-GCs. Moreover, our data revealed that exosomes derived from TMZ-GCs also had obvious effects on inducing the TMZ resistance and proliferation of GCs. Moreover, we revealed that the packaging of circNT5E into exosomes can be driven by hnRNP A1.

Conclusions
Collectively, our findings proved that exosomal circNT5E transferred in a manner mediated by hnRNPA1 could accelerate TMZ resistance by targeting miR-153 in GCs, indicating that exosomal circNT5E is a therapeutic target for TMZ-resistant glioma.
Enhancing methane sensing with NDIR technology: Current trends and future prospects
Authors: Fu Li , You Shixi , Li Guangjun , Fan Zengchang 
Published: November 2023

Abstract
This study presents an in-depth review of non-dispersive infrared (NDIR) sensors for methane detection, focusing on their principles of operation, performance characteristics, advanced signal processing techniques, multi-gas detection capabilities, and applications in various industries. NDIR sensors offer significant advantages in methane sensing, including high sensitivity, selectivity, and long-term stability. The underlying principles of NDIR sensors involve measuring the absorption of infrared radiation by the target gas molecules, leading to precise and reliable methane concentration measurements. Advanced signal processing techniques, such as single-frequency filtering and wavelet filtering algorithms, have been explored to improve the performance of the sensor by reducing noise, enhancing the signal-to-noise ratio, and achieving more accurate results. In the context of multi-gas detection, NDIR sensors face challenges due to overlapping absorption spectra. However, various solutions, including narrow-band optical bandpass filters, gas filter correlation techniques, and machine learning algorithms, have been proposed to address these issues effectively. This study delves into specific applications of NDIR sensors in various industries, such as coal mines, wastewater treatment plants, and agriculture. In these settings, NDIR sensors have demonstrated their reliability, accuracy, and real-time monitoring capabilities, contributing to environmental protection, safety, and energy recovery. Furthermore, the anticipated future trends and developments in NDIR methane detection technology are explored, including increased miniaturization, integration with artificial intelligence, improvements in power efficiency, and the development of multi-gas NDIR sensors. These advancements are expected to further enhance the capabilities and widespread adoption of NDIR sensors in methane detection applications.