bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advancing maturity modeling for precision oncology
Authors: Hoffman-Peterson Ariella , Marathe Megh , Ackerman Mark S. , Barnett William , Hamasha Reema , Kang April , Sawant Kashmira , Flynn Allen , Platt Jodyn E. 
Published: December 2023

Abstract

Introduction:
This study aimed to map the maturity of precision oncology as an example of a Learning Health System by understanding the current state of practice, tools and informatics, and barriers and facilitators of maturity.

Methods:
We conducted semi-structured interviews with 34 professionals (e.g., clinicians, pathologists, and program managers) involved in Molecular Tumor Boards (MTBs). Interviewees were recruited through outreach at 3 large academic medical centers (AMCs) (n = 16) and a Next Generation Sequencing (NGS) company (n = 18). Interviewees were asked about their roles and relationships with MTBs, processes and tools used, and institutional practices. The interviews were then coded and analyzed to understand the variation in maturity across the evolving field of precision oncology.

Results:
The findings provide insight into the present level of maturity in the precision oncology field, including the state of tooling and informatics within the same domain, the effects of the critical environment on overall maturity, and prospective approaches to enhance maturity of the field. We found that maturity is relatively low, but continuing to evolve, across these dimensions due to the resource-intensive and complex sociotechnical infrastructure required to advance maturity of the field and to fully close learning loops.

Conclusion:
Our findings advance the field by defining and contextualizing the current state of maturity and potential future strategies for advancing precision oncology, providing a framework to examine how learning health systems mature, and furthering the development of maturity models with new evidence.
Repairing the scaffolding: women authors in Paleobiology
Authors: Arens Nan Crystal , Holguin Levi , Sandoval Natalie 
Published: December 2023

AbstractWomen are underrepresented in paleontology. Despite more women students, representation at senior levels remains low. To advance professionally, scientists must disseminate their research through peer-reviewed publications. We examine gendered authorship patterns in Paleobiology to ask whether the publishing infrastructure supports the Paleontological Society's gender-equity goals. We reviewed all papers published in Paleobiology from its inception in 1975 through 2021. For each paper, we recorded each author, the author's position in the author list, and the total number of authors on each paper. We coded gender based on a combination of personal communication and pronouns used in publicly available information. We compared author demographics with anonymized membership data from the Paleontological Society. Over the journal's run, the number of authors per paper increased due to cultural shifts toward collaborative work and acknowledging student contributions with coauthorship. These trends contribute to proportionally more women authors, beginning in the early 2000s. Despite these increases, women remain chronically underrepresented. In 2018, 2019, and 2021, the proportion of women authors in Paleobiology paralleled membership in the Paleontological Society. However, in 2020, Paleobiology published fewer women authors than expected based on society membership. This echoes declines in women's scholarly productivity in the first year of the COVID-19 pandemic observed across many disciplines. We offer four recommendations: (1) practice double-anonymous peer review; (2) recruit editors from diverse backgrounds who invite reviewers with diverse backgrounds; (3) democratize manuscript review by selecting reviewers from a disaggregated reviewer database; and (4) gather and analyze demographic data for both submissions and publications.
Winter-Quartering Tribes: Nomad–Peasant Relations in the Northeastern Frontiers of the Ottoman Empire (1800s–1850s)
Authors: Koç Yener 
Published: December 2023

AbstractFocusing on the winter quartering of Kurdish nomadic tribes among peasant villages, this article discusses the patterns of Kurdish nomadism and nomad–peasant relations in the Ottoman sanjaks of Muş, Bayezid, and Van during the first half of the nineteenth century. It argues that the political structure of these regions and the requirements of animal husbandry among the nomads not only created a distinct pattern of nomadism among the Kurdish tribes, but also led to the polarization of relations between nomads and peasants. Moreover, the article observes how nomad–settled, tribe–peasant relations in these regions evolved as a result of the gradual sedentarization of the pastoral nomads and related changes in their subsistence economies starting from the mid-nineteenth century. Finally, this article provides a background for a better understanding of the intercommunal tensions and conflicts over land in the Ottoman Empire of the late nineteenth and early twentieth centuries.
Politics in Legal Disguise
Authors: Friedmann Daniel 
Published: December 2023

AbstractThe article discusses the current legal-political crisis in Israel against the backdrop of the judicial and political powers that have led to the present situation. The disastrous Yom Kippur War of 1973 weakened the government and public confidence in the political institutions. The weaknesses of the government enabled the Supreme Court to carry out a judicial revolution, which completely changed the country's legal system. The legal revolution entered a new stage when the Supreme Court held that the Basic Laws form part of Israel's constitution. This judicially created constitution opened the way for judicial review of legislation. Its weakness stems from the fact that Basic Laws are legislated in much the same way as ordinary legislation. As a result, the Knesset can easily override any ruling of the Court that voids a statute, by amending the relevant Basic Law. The Court is now struggling to find a means of gaining some control over the legislation of Basic Laws. At the same time, the present government declared its intention to carry out legal reforms that are in effect a counter-revolution to the judicial revolution. The article examines how the fluctuation in the political support of the Court affects its decisions.
Palliative care in the treatment of women with breast cancer: A scoping review
Authors: Velasco Yanez Romel Jonathan , Carvalho Fernandes Ana Fátima , de Freitas Corpes Erilaine , Moura Barbosa Castro Régia Christina , Sixsmith Judith , Lopes-Júnior Luís Carlos 
Published: December 2023

AbstractObjectivesRecent studies on the quality of life in women with breast cancer show a high prevalence of signs and symptoms that should be the focus of palliative care (PC), leading us to question the current role they play in addressing breast cancer. Therefore, the objective of this review is to map the scope of available literature on the role of PC in the treatment of women with breast cancer.MethodsThis is a methodologically guided scoping review by the Joanna Briggs Institute and adapted to the PRISMA Extension for Scoping Reviews (PRISMA-ScR) Checklist for report writing. Systematic searches were conducted in 8 databases, an electronic repository, and gray literature. The searches were conducted with the support of a librarian. The study selection was managed through the RAYYAN software in a blind and independent manner by 2 reviewers. The extracted data were analyzed using the qualitative thematic analysis technique and discussed through textual categories.ResultsA total of 9,812 studies were identified, of which only 136 articles and 3 sources of gray literature are included in this review. In terms of general characteristics, the majority were published in the USA (35.7%), had a cross-sectional design (44.8%), and were abstracts presented at scientific events (19.6%). The majority of interventions focused on palliative radiotherapy (13.6%). Thematic analysis identified 14 themes and 12 subthemes.Significance of resultsOur findings offer a comprehensive view of the evidence on PC in the treatment of breast cancer. Although a methodological quality assessment was not conducted, these results could guide professionals interested in the topic to position themselves in the current context. Additionally, a quick synthesis of recommendations on different palliative therapies is provided, which should be critically observed. Finally, multiple knowledge gaps are highlighted, which could be used for the development of future studies in this field.
Cortico-muscular connectivity is modulated by passive and active Lokomat-assisted Gait
Authors: Artoni Fiorenzo , Cometa Andrea , Dalise Stefania , Azzollini Valentina , Micera Silvestro , Chisari Carmelo 
Published: December 2023

AbstractThe effects of robotic-assisted gait (RAG) training, besides conventional therapy, on neuroplasticity mechanisms and cortical integration in locomotion are still uncertain. To advance our knowledge on the matter, we determined the involvement of motor cortical areas in the control of muscle activity in healthy subjects, during RAG with Lokomat, both with maximal guidance force (100 GF—passive RAG) and without guidance force (0 GF—active RAG) as customary in rehabilitation treatments. We applied a novel cortico-muscular connectivity estimation procedure, based on Partial Directed Coherence, to jointly study source localized EEG and EMG activity during rest (standing) and active/passive RAG. We found greater cortico-cortical connectivity, with higher path length and tendency toward segregation during rest than in both RAG conditions, for all frequency bands except for delta. We also found higher cortico-muscular connectivity in distal muscles during swing (0 GF), and stance (100 GF), highlighting the importance of direct supraspinal control to maintain balance, even when gait is supported by a robotic exoskeleton. Source-localized connectivity shows that this control is driven mainly by the parietal and frontal lobes. The involvement of many cortical areas also in passive RAG (100 GF) justifies the use of the 100 GF RAG training for neurorehabilitation, with the aim of enhancing cortical-muscle connections and driving neural plasticity in neurological patients.
The effect of rotational velocity on rotational traction across a range of artificial turf surface systems
Authors: McGowan Harry , Fleming Paul , Pak Jae-Hwi , James David , Forrester Steph 
Published: December 2023

AbstractMechanical testing by sporting governing bodies ensures artificial turf surfaces conform with performance standards. Rotational traction is measured using two equivalent devices: a rotational traction tester (RTT) and a lightweight rotational traction tester (LRTT). The devices differ in target rotational velocity; 72 deg/s for the RTT and 30 deg/s for the LRTT. The purpose of this study was to investigate the influence of rotational velocity on peak torque during rotational traction testing. An automated rotational traction tester examined nine rotational velocities between 10 and 210 deg/s, and ten artificial turf surface systems with a range of performance infill materials, infill depths and carpet specifications. Rotations at 10 deg/s produced the lowest peak torques on nine of the ten surfaces. Infill materials with intrinsic viscoelastic properties produced significantly higher peak torques at higher rotational velocities, whereas less elastic infill materials saw no significant increase in peak torque. A mean difference in peak torque of 2.6 Nm was found between the target velocities of the RTT and LRTT. The results support the synchronisation of target velocities for the RTT and LRTT. During standards testing, trials completed below a particular velocity should be repeated to negate velocity effects on peak torque.
Application of double low-dose mode in left atrial-pulmonary venous computed tomography angiography
Authors: Zhang Changjiang , Zhang Wei , Shi Kaihu , Chen Jingya 
Published: December 2023

AbstractThis study adopted a 256-slice iCT scanner with the double low-dose mode in left atrial-pulmonary venous computed tomography angiography (CTA) and explored its effect on image quality. 120 patients were included and randomly classified into the Observation group and Control group. Patients in the Control group underwent routine left atrial CTA, while patients in the Observation group performed a double low-dose mode. Other scanning parameters were consistent in the two groups. The Full model-based iterative reconstruction (MBIR) technique was applied to fulfill image reconstruction in observation group. Continuous variables, ordered categorical variables were analyzed by statistical test. The CT values of left atrial in the Observation group were significantly higher than those in the Control group. The exposure doses (ED) and iodine intake were lower in the Observation group, as compared to the Control group. The left atrial-pulmonary venous CTA with the 256-slice iCT scanner in a double low-dose mode can reduce the ED of radiation and iodine contrast while providing high quality images. Comparatively, the ED in the Observation group was reduced by 13% compared with the control, and the iodine intake was reduced by approximately 33%.
An ensemble-based machine learning solution for imbalanced multiclass dataset during lithology log generation
Authors: Jamshidi Gohari Mohammad Saleh , Emami Niri Mohammad , Sadeghnejad Saeid , Ghiasi‑Freez Javad 
Published: December 2023

AbstractThe lithology log, an integral component of the master log, graphically portrays the encountered lithological sequence during drilling operations. In addition to offering real-time cross-sectional insights, lithology logs greatly aid in correlating and evaluating multiple sections efficiently. This paper introduces a novel workflow reliant on an enhanced weighted average ensemble approach for producing high-resolution lithology logs. The research contends with a challenging multiclass imbalanced lithofacies distribution emerging from substantial heterogeneities within subsurface geological structures. Typically, methods to handle imbalanced data, e.g., cost-sensitive learning (CSL), are tailored for issues encountered in binary classification. Error correcting output code (ECOC) originates from decomposition strategies, effectively breaking down multiclass problems into numerous binary subproblems. The database comprises conventional well logs and lithology logs obtained from five proximate wells within a Middle Eastern oilfield. Utilizing well-known machine learning (ML) algorithms, such as support vector machine (SVM), random forest (RF), decision tree (DT), logistic regression (LR), and extreme gradient boosting (XGBoost), as baseline classifiers, this study aims to enhance the accurate prediction of underground lithofacies. Upon recognizing a blind well, the data from the remaining four wells are utilized to train the ML algorithms. After integrating ECOC and CSL techniques with the baseline classifiers, they undergo evaluation. In the initial assessment, both RF and SVM demonstrated superior performance, prompting the development of an enhanced weighted average ensemble based on them. The comprehensive numerical and visual analysis corroborates the outstanding performance of the developed ensemble. The average Kappa statistic of 84.50%, signifying almost-perfect agreement, and mean F-measures of 91.04% emphasize the robustness of the designed ensemble-based workflow during the evaluation of blind well data.
Wound Healing and Special Considerations for the Professional and Performing Voice
Authors: Dueppen Abigail , Joshi Ashwini 
Published: December 2023

Purpose:
The purpose of this article is to review the wound healing process of the vocal fold following phonomicrosurgery to remove benign vocal fold lesions in professional voice users. Understanding this process and the risk of developing scar tissue at the injury site is important for treatment of these individuals. This review also highlights special considerations during the postinjury rehabilitation period and the unique vocal loading tasks and needs of performing voice users. The goal of this article is to provide clinical tools for wound healing education to nonvoice-specialized speech-language pathologists to inform their rehabilitation of the professional and performing voice user.

Conclusions:
Implications intrinsic to vocal fold physiology and the stages of wound healing necessitate the avoidance of scar tissue with a rehabilitation plan tailored to the unique vocal loading demands of professional and performing voice users. There is a need to develop specific rehabilitation protocols that are genre-specific to aid in the individual treatment of the elite vocal athlete.
Interdisziplinäre Behandlung einer Patientin mit
hemimandibulärer Hyperplasie
Authors: Ziemann Fabian , Knauth Jessica , Nottmeier Cita , Köhne Till 
Published: December 2023

ZusammenfassungMandibuläre Asymmetrien die mit persistierendem Unterkieferwachstum
assoziiert sind, manifestieren sich häufig im jungen Erwachsenenalter.
Konservativen Therapieansätzen sind diese Dysgnathien nicht mehr
zugänglich. Therapie der Wahl stellt ein kombiniert
kieferorthopädisch-kieferchirurgisches Konzept dar. Der nachfolgend
dokumentierte Fall soll ein mögliches Therapiekonzept am Beispiel einer
jungen Patientin mir hemimandibulärer Hyperplasie veranschaulichen.
Fasten
Authors: Hanslian Etienne , Koppold Daniela , Michalsen Andreas 
Published: December 2023

ZUSAMMENFASSUNGFasten als Therapie hat im letzten Jahrzehnt durch eine Fülle an Grundlagenstudien und experimentellen Arbeiten sowie zunehmende klinische Forschung seinen Einzug in die moderne Medizin gehalten. Es ist ein Verfahren mit jahrtausendealter Tradition und dadurch verschiedenartigen Durchführungsmöglichkeiten. Gemeinsam ist ihnen die Reduktion der täglichen Nahrungsaufnahme für begrenzte Zeit. Diese hat vielfältige Wirkungen auf Stoffwechsel, Zellen und Organsysteme, die es zu einem potenten Mittel im ärztlichen Handeln machen können.
Opioid Prescribing for Chronic Musculoskeletal Conditions: Trends over Time and Implementation of Safe Opioid-Prescribing Practices
Authors: Wally Meghan K. , Thompson Michael E. , Odum Susan , Kazemi Donna M. , Hsu Joseph R. , Seymour Rachel B. ,   and PRIMUM Group
Published: December 2023

Abstract
Objectives This study aimed (1) to determine the impact of a clinical decision support (CDS) tool on rate of opioid prescribing and opioid dose for patients with chronic musculoskeletal conditions and (2) to identify prescriber and facility characteristics associated with adherence to the Centers for Disease Control and Prevention guideline for prescribing opioids for chronic pain in this population.We conducted an interrupted time series analysis to assess trends in percentage of patients from 2016 to 2020, receiving an opioid and the average opioid dose, as well as the change associated with implementation of the CDS toolkit. We conducted a retrospective cohort study to assess the association between prescriber and facility characteristics and safe opioid-prescribing practices.
Methods We assessed the impact of the CDS intervention on percent of patients receiving an opioid and average opioid dose (morphine milligram equivalents). We operationalized safe opioid prescribing as a composite score of several behaviors (i.e., prescribing naloxone, initiating a pain agreement, prescribing <90 MME, avoiding extended-release prescriptions for opioid-naïve patients, and avoiding coprescribing opioids and benzodiazepines) and used a hierarchical linear regression model to assess associations between prescriber and facility characteristics and safe opioid prescribing.
Results This CDS intervention had a modest but statistically significant 1.6% reduction on the percent of patients (n = 1,290,746) receiving an opioid (mean: 15% preintervention; 10% postintervention). The average dose of opioid prescriptions did not significantly change. Advanced practice providers and prescribers with higher percentages of patients aged 18 to 64 exhibited safer opioid prescribing, while prescribers with higher percentages of white patients and larger numbers of patients on opioids exhibited less safe opioid prescribing.
Conclusion A CDS intervention was associated with a small improvement in percent of patients receiving an opioid, but not on average dose. Clinicians are not prescribing opioids for chronic musculoskeletal conditions frequently, when they do, they are generally adhering to guidelines.
Lessons from the Netherlands for Australia: cross-country comparison of trends in antidepressant dispensing 2013–2021 and contextual factors influencing prescribing
Authors: Wallis Katharine A. , Dikken Pieter J. S. , Sooriyaarachchi Piumika , Bohnen Arthur M. , Donald Maria 
Published: December 2023

Background There is concern internationally about increasing antidepressant use. Most antidepressants are prescribed in general practice. The aim of this study was to compare trends in antidepressant dispensing in Australia and the Netherlands over the 9 years from 2013 to 2021, and to explore reasons for differences. Methods A convergent mixed methods study including analysis of publicly available antidepressant dispensing data obtained from Australia’s Pharmaceutical Benefits Scheme and Repatriation Pharmaceutical Benefits Scheme and the Dutch Foundation for Pharmaceutical Statistics and a search of relevant literature to compare contextual factors influencing prescribing were undertaken. Results In 2013, antidepressant dispensing rates in Australia were nearly twice as high as those in the Netherlands (82.5 versus 44.3 DDD/1000/day) and increased to be more than twice as high by 2021 (115.6 versus 48.8 DDD/1000/day). Antidepressant dispensing increased by 40% in Australia over the nine study years, but by only 10% in the Netherlands. Our scan of the literature confirms that while population factors, health system structure, and clinical guideline recommendations are largely consistent across the two countries, a multifaceted approach in the Netherlands involving improved access to non-pharmacological alternatives, initiatives targeting safer antidepressant prescribing, and tight regulation of pharmaceutical industry influence on prescribers, has successfully curtailed increasing antidepressant use. Conclusions Australia may learn from the Netherlands’ approach to redress increasing antidepressant use.
Abrupt grammatical reorganization of an emergent sign language
Authors: German Austin 
Published: December 2023

Abstract
This study traces the development of discrete, combinatorial structure in Zinacantec Family Homesign (‘Z Sign’), a
sign language developed since the 1970s by several deaf siblings in Mexico (Haviland
2020b), focusing on the expression of motion. The results reveal that the first signer, who generated a homesign system
without access to language models, represents motion events holistically. Later-born signers, who acquired this homesign system
from infancy, distribute the components of motion events over sequences of discrete signs. Furthermore, later-born signers exhibit
greater regularity of form-meaning mappings and increased articulatory efficiency. Importantly, these changes occur abruptly
between the first- and second-born signers, rather than incrementally across signers. This study extends previous findings for
Nicaraguan Sign Language (Senghas et al. 2004) to a social group of a much smaller
scale, suggesting that the parallel processes of cultural transmission and language acquisition drive language emergence,
regardless of community size.