bluuebunny/crossref_metadata_2025_split huggingface dataset:
Вплив занять спортивними іграми на якість життя студентської молоді
Authors: Сікорська Лілія , Вознюк Тетяна 
Published: January 2025

Topicality. The study of the impact of sports games on student youth provides an understanding of the possibility of practical application of sports games or individual sports game tools to normalize their physical and psychological state. The purpose of the study is to determine the impact of sports games on the quality of life of student youth according to indicators of emotional state. Material and methods of the study. The study involved 150 students (male) of the 1st year of pedagogical specialties who expressed a desire to engage in optional sports games: table tennis (n=13), volleyball (n=28), football (n=29); power sports (n=25) and athletics (n=21), as well as 34 students who, due to lack of desire, were not involved in optional classes. The SAN method was used to determine indicators of emotional state (well-being, activity, mood) at the beginning and end of the academic year. Results of the study. During the academic year, there were certain changes in the indicators of well-being, activity and mood of applicants of all three groups. Although in essence they had a different nature. In applicants who were engaged in various sports, all indicators changed positively. At the same time, a larger percentage of applicants with the highest degree of positively expressed assessments was found in those who were engaged in sports games. Applicants who were not engaged in optional groups, on the contrary, identified negative changes in their state. Conclusions. During the year of optional classes in game sports, the number of applicants with a negative emotional state decreased from 19 to 5 %, with an extremely positive degree of expression increased from 27 to 42 %. Positive changes were also found in students who were engaged in individual sports. Students who did not attend optional physical education classes showed a deterioration in well-being – from 28 % at the beginning to 36 % at the end of the academic year, and in mood – from 14 to 18 %, respectively.
Partnership between national statistics offices and academics to increase official statistical literacy
Authors: Harraway J.A. , Forbes S.D. 
Published: January 2025

Statistics New Zealand is actively involved in raising the statistical capability of key groups of users. Current priority groups are government, the media and Maori (indigenous New Zealand) and, in the recent past, schools and small businesses. Initiatives designed to support statistical literacy development include synthetic unit record files (SURFs), confidentialized unit record files (CURFs), postgraduate student work placements, funding for the CensusAtSchool project, a National Certificate of Official Statistics for public sector staff, and an honours/masters paper in official statistics. Almost all the educational initiatives implemented so far have been developed collaboratively with educational institutions through a network of academics in official statistics (NAOS) established in 2006. Members have been involved in the design, implementation, delivery and assessment of courses for qualification as well as presenting short (one- or two-day) courses for government employees on topics such as ethics and legislation, interpreting opinion polls and demography. A particular focus of this paper is the postgraduate course in Official Statistics introduced in 2011. This used advanced video-conferencing with teaching staff and students at five New Zealand universities. The course has been beneficial for Statistics New Zealand, universities and students. Feedback from students is also reported.
How to fulfil user needs – from industrial production of statistics to production of knowledge
Authors: Thygesen Lars , Nielsen Mogens Grosen 
Published: January 2025

Statistical organisations disseminate statistics to an extent never seen before. We have developed tools that handle increasing amounts of data. However, in the production of statistics we tend to look inward; our primary focus is on whether macro figures are reasonable and published in time. We don't take the user`s situation sufficiently into account. According to an in-depth user-consultation, we have found that it is an urgent task to uncover needs and to give end-users better assistance when they use statistics or wish to find relevant statistics. Is it just a question of improving our services towards users or are we facing more fundamental problems due to political, social and technological changes for users and producers of statistics? Our hypothesis is that the growing political, social and technological complexity should be reflected in the way we work and in the choices of statistics we produce in order to fulfil needs in a knowledge-based society. The paper first presents user-consultations conducted at Statistics Denmark. Hereafter follow four themes that the authors find relevant for the fulfilment of user needs in a society where knowledge plays an important role. The four themes are: 1) dynamic use of registers, 2) from silos to dynamic processes, 3) quality and user needs, and 4) metadata and user needs. Finally the insight from user-consultations and related reflections under the four themes are put together. Business Process Management is suggested as an"umbrella-perspective" uniting the various disciplines that need to be put into play in order to reach a situation, where the production of statistics can be organised in way that moves toward a fulfilment of needs identified in the user-consultations. The insights have been put into practice in a pilot project at Statistics Denmark. A description of the project and lessons learned is provided. The paper concludes that user-consultations and subsequent reflections call for continuously investigating user needs, enhancement of the use of registers, better organisation of processes and more focus on quality and metadata.
Safeguarding trust in statistics and the new statistical voice
Authors: Nymand-Andersen Per 
Published: January 2025

The world of statistics is continually challenged by its remit to reflect and explain complex financial and economic phenomena, as well as their relative importance in, and impact on, society. Furthermore, changes to users' needs and working patterns – which stem from the increased use of collaborative technologies – also present challenges in terms of the way that statistics are communicated to users, be they the political establishment, professional users, the media, academia or the general public. In contributing to an involved, knowledge-based society, trustworthy, reliable and independent statistics represent a fundamental cornerstone of modern democracies. This cannot be taken for granted and further efforts are needed, in the context of democratic development, to permanently shield statistics from short-term electoral cycles. This article highlights the principal components of generating trust in statistics within modern democracies and furthermore highlights that a new two-way statistical communication strategy is needed designed to reach and engage users in statistics.
The globalisation of statistical content
Authors: Grossenbacher Armin 
Published: January 2025

Statistics are an excellent tool for giving fast, precise and universally understandable information. It is the explicit mission of modern statistical agencies to disseminate their information to specific target groups as well as to a broad public. But how can the accessibility of statistics and likewise the visibility and acceptance of the brand of official statistics be ensured? And this in a period where statistical content is disseminated more and more by third party providers and where new dissemination tools open promising opportunities – where statistical content becomes increasingly globalised. The article gives an overview of the impact the Internet Revolution of the nineties had on the dissemination of official statistics, shows some of the directions web technologies have taken since then and points out challenges and opportunities for official statistics. Special focus is made on how Web 2.0 and Semantic Web are contributing to changing the traditional dissemination paradigm and to opening new opportunities by broadening, globalising and facilitating access to official statistics. In order to be present and to display its brand of quality, semantically linked data are becoming increasingly indispensable; there is a clear need to harmonise metadata further and to introduce these structures into dissemination offers.
Automated data collection from web sources for official statistics: First experiences
Authors: Hoekstra Rutger , ten Bosch Olav , Harteveld Frank 
Published: January 2025

Summary: As the internet grows National Statistical Institutes (NSI) are increasingly using data from the internet as a source for their statistics. This paper describes the first experiences of Statistics Netherlands in the automated collection of data from web pages. First, we explore the feasibility of this method of data collection for NSI's. We conclude that from a technical point of view this type of data collection is possible. Furthermore, the use of website data is probably legal. It is also concluded, that methodological applicability will have to be assessed on a case by case basis. Second, we investigate the desirability of this type of data collection. On the basis of six case studies tentative conclusions are drawn. Our results show that the cost of reprogramming the robots in case of a site change and the initial investment in the manual process are the most important factors. Furthermore, we conclude that efficiency gains are likely to occur due to the learning-by-doing and scale effects. Finally, we conclude that the main advantages of internetrobots are in applications with large amounts of data(leading to increases in quality, frequency and speed). This will lead to new statistics but also advance the methodological aspects of certain measurement issues.
Forecasting the Detection of Lyman-alpha Forest Weak Lensing from the Dark Energy Spectroscopic Instrument and Other Future Surveys
Authors: Shaw Patrick , Croft Rupert A. C. , Metcalf R. Benton 
Published: January 2025

The apparent angular positions of quasars are deflected on the sky by the gravitational field sourced by foreground matter. This weak lensing effect is measurable through the distortions it introduces in the lensed quasar spectra. Discrepancies in the statistics of the Lyman- α forest spectral absorption features can be used to reconstruct the foreground lensing potential. We extend the study of this method of Lyman- α forest weak gravitational lensing to lower angular forest spectrum source densities than previous work. We evaluate the performance of the Lyman- α lensing estimator of Metcalf et al. (2020) on mock data based on the angular forest source density ( 50 per square degree) and volume (about 700,000 spectra total) of the DESI survey. We simulate the foreground galaxy distribution and lensing potentials with redshift evolution approximated by N-body simulation and simulate Gaussian-random Lyman- α forests to produce mock data for the entire DESI footprint. By correlating the foreground galaxy distribution with the potential reconstructed by the estimator, we find that a weak lensing detection with signal to noise of ∼4 will be possible with the full DESI data. We show that spectral surveys with low density and high volume are promising candidates for forest weak lensing in addition to the high resolution data that have been considered in previous work. We present forecasts for future spectral surveys and show that with larger datasets a detection with signal to noise >10 will be possible.
Evaluation of phosphate sources using ruminal fiber transit kinetics methodology
Authors: Couto Claudiney de Jesus , Braga Bruna Cardoso , Gomes Raphael dos Santos , Tamy Wagner Pessanha , Villela Severino Delmar Junqueira , Leonel Fernando de Paula 
Published: January 2025

IntroductionSince the low phosphorus content is one of the reasons for the low degradation of fiber in roughage such as pasture and by-products, fiber transit kinetics can be an important tool to evaluate differences in digestion depending on phosphorus supplementation with different sources. The objective was to compare the potential of different sources of phosphorus in promoting improvement in fiber digestibility parameters.MethodsFeeds low in phosphorus were chosen to compose the basal diet. Five crossbred heifers with an average initial weight of 150 ± 8.2 kg were used, randomly distributed in a 5x5 Latin square. The treatments were: negative control (NC) without supplementary phosphorus; dicalcium phosphate from igneous rock with sulfuric acidulation, neutralization with limestone, and the show physical form of microgranules (ISLG); Dicalcium phosphate from igneous rock with sulfuric acidulation, neutralization with hydrated lime, and the physical form of powder (ISLhP); Dicalcium phosphate from sedimentary rock with hydrochloric acidulation, neutralization with limestone, and the micro-granulated show physical form (SeCLG); Dicalcium phosphate from the monocalcium phosphate and hydrated lime reaction adjusted with phosphoric acid, and the powder physical form (MLhPaP). The parameters of the kinetics transit of particles with use of the chromium marker, fixed to the roughage cell wall and subsequent recovery of the marker in the heifer feces, were determined.Results and discussionThe ISLG resulted in a higher (p&lt;0.05) passage rate of particles from the solid to the liquid phase in the rumen-reticulum. There was no difference (p&gt;0.05) between the diets for the time that indigestible particles spent from ruminal escape to their first appearance in feces. The longest retention time (p&lt;0.05) of solid particles in the rumen-reticulum was detected in animals that received NC diet. In conclusion, heifers that do not receive supplemental phosphorus exhibited poorer fiber processing and dry matter intake (DMI).
Role of glucocorticoid receptor expression in Chronic Chagas Cardiomyopathy: implications for inflammation and cardiac hypertrophy
Authors: González Florencia B. , Pacini Antonella , Castro Araceli , Lioi Susana , Villar Silvina R. , D’Attilio Luciano , Leiva Rodolfo D. , Favaloro Liliana , Bottasso Oscar A. , Vigliano Carlos A. , Pérez Ana Rosa 
Published: January 2025

IntroductionChronic Chagasic Cardiomyopathy (CCC) has an infectious and inflammatory nature. Recent data also suggest an association with altered regulation of glucocorticoid (GC)-mediated circuits failing to control systemic inflammation. However, the involvement of glucocorticoid receptors (GR) and their isoforms have been unexplored.Materials and methodsThe expression of GR-α/β isoforms, 11β-hydroxysteroid dehydrogenase type-1 (11β-HSD1), inflammatory cytokines, and the GC-regulated gene tristetraprolin (TTP) in peripheral blood mononuclear cells (PBMCs) as well as GR immunoreactivity in the myocardium from CCC individuals were evaluated by qPCR and immunohistochemistry respectively. Heart control samples with no evidence of structural heart disease and from ischemic cardiomyopathy patients were included. The presence of inflammatory infiltrates and fibrosis were also recorded.ResultsGR-α was expressed similarly in the PBMCs from Co and CCC individuals, but 11β-HSD1 expression was increased only in CCC, conjointly with enhanced ratios of IL-6/TTP and IFN-γ/TTP. In the inflamed myocardium from CCC patients, positive GR expression correlated with the intensity of the inflammatory infiltrate and cardiac hypertrophy.ConclusionThe infectious and inflammatory nature of CCC pathology seems strongly connected with the expression of GR in cardiac tissue samples, providing a stimulating background for further studies addressed to elucidate the influence of GR expression and function on CCC pathophysiology and cardiomyocyte hypertrophy.
Women's preferences, impacts, and satisfaction with companion support during labour and delivery experiences in Oman
Authors: Alwahaibi Nasar , Alajaimi Fatema , Alhabsi Hoor , Alkalbani Alzahra , Aljulandani Rodina 
Published: January 2025

BackgroundThis is the first study to combine both the women's preferences, impacts, and satisfaction during their labour and delivery experience and their companions for their role and impacts. Previously published papers examined either the preferences of pregnant women or those of their companions, which are few. Women's preferences, impacts, and satisfaction with their companions during labour and delivery were evaluated in this study.MethodsThis cross-sectional observational study was conducted between June 2022 and April 2024. As part of this study, labouring women as well as their companions were interviewed separately face-to-face in a private place, and all answers were kept anonymous and confidential. We evaluated each category separately based on two separate sections.ResultsThis study included a total of 444 labouring women and an equal number of companions, with mean ages of 32.25 years and 42.66 years, respectively. The majority of women and companions were housewives with college degrees. Among companions, mothers and husbands were the most preferred, and they were typically present from admission to discharge. Among women who had companions, 84.1% reported feeling calmer and more comfortable. 91.9% of companions supported women with encouraging words, and 92.6% perceived their support as highly beneficial to the women. Women expressed 94.8% satisfaction with the medical staff and 87.6% satisfaction with hospital services, while companions reported 96.6% and 74.8% satisfaction with the medical staff and hospital services, respectively.ConclusionsLabouring women appreciated and valued the presence of companions during childbirth as they had positive impacts. Mothers are the most preferred companions and preferred to be present from admission until discharge. Most companions support their labouring women by encouraging wards. Labouring women and companions were satisfied with the medical team and services provided to them. The presence and role of companions during the childbirth process are crucial and warrant emphasis.
Transcriptional analysis of murine biliary atresia identifies macrophage heterogeneity and subset-specific macrophage functions
Authors: Gromer Kyle D. , Chen Shang-Yang , Gadhvi Gaurav , Feng Liang , Shearn Colin , Antala Swati , Wechsler Joshua B. , Cuda Carla M. , Mack Cara L. , Sokol Ronald J. , Janssen William J. , Green Richard M. , Perlman Harris , Winter Deborah R. , Taylor Sarah A. 
Published: January 2025

IntroductionMacrophages play an important role in disease progression of pediatric cholestatic liver disease, particularly biliary atresia (BA); however, the restorative versus pathogenic role for precise macrophage subsets remains poorly defined. We aimed to distinguish the transcriptional profiles and roles of defined macrophage subset(s) in murine BA.MethodsWe used multiparameter flow cytometry and RNA-sequencing analysis to profile recruited CD11bhiCD64+ hepatic macrophages by cell surface expression of MHCII and Ly6c in the Rhesus rotavirus (RRV)-induced murine model of BA versus saline controls. Modulation of macrophage numbers via intra-peritoneal injections of clodronate-loaded liposomes was performed to determine the association between macrophage numbers and histologic injury (Ishak score).ResultsLy6c+ macrophages demonstrated the greatest increase in numbers and percent of total macrophages in murine BA versus saline controls whereas MHCII+ macrophages decreased. Transcriptional changes in murine BA MHCII+ macrophages included reduced expression of the Kupffer cell gene signature, lower expression of genes involved in homeostatic processes, and increased expression of genes involved in inflammatory processes. Ly6c+ macrophages in murine BA showed increased expression for Hif1a and other genes involved in the cellular response to hypoxia. Among all subsets, the number of Ly6c+ macrophages exhibited the strongest correlation with severity of histologic liver injury by Ishak score.ConclusionsOur data identify specific pathways upregulated in Ly6c vs MHCII+ macrophage subsets in murine BA. Transcriptional similarities between murine BA and human cholestatic macrophages may enable translation of future mechanistic studies to new macrophage subset-specific therapies.
Disulfidptosis as a key regulator of glioblastoma progression and immune cell impairment
Authors: Shu Yifu , Li Jing 
Published: January 2025

BackgroundGlioblastoma, associated with poor prognosis and impaired immune function, shows potential interactions between newly identified disulfidptosis mechanisms and T cell exhaustion, yet these remain understudied.MethodsKey genes were identified using Lasso regression, followed by multivariate analysis to develop a prognostic model. Single-cell pseudotemporal analysis explored disulfidptosis T-cell exhaustion (Tex) signaling in cell differentiation. Immune infiltration was assessed via ssGSEA, while transwell assays and immunofluorescence examined the effects of disulfidptosis-Tex genes on glioma cell behavior and immune response.ResultsEleven disulfidptosis-Tex genes were found critical for glioblastoma survival outcomes. This gene set underpinned a model predicting patient prognosis. Single-cell analysis showed high disulfidptosis-Tex activity in endothelial cells. Memory T cell populations were linked to these genes. SMC4 inhibition reduced LN299 cell migration and increased chemotherapy sensitivity, decreasing CD4 and CD8 T cell activation.ConclusionsDisulfidptosis-Tex genes are pivotal in glioblastoma progression and immune interactions, offering new avenues for improving anti-glioblastoma therapies through modulation of T cell exhaustion.