bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Breathable, Reliable, and Flexible Siloxene Incorporated Porous SEBS‐Based Triboelectric Nanogenerator for Human–Machine Interactions
Authors: Shrestha Kumar , Pradhan Gagan Bahadur , Asaduzzaman Md , Reza Md Selim , Bhatta Trilochan , Kim Hongseok , Lee Yeyeong , Park Jae Y. 
Published: December 2023

AbstractThe breathability of wearable sensors is of utmost necessity as it facilitates heat dissipation and sweat evaporation from the skin–sensor interface for improving the user's comfort and minimizing the inflammation risk. In this work, a Siloxene/porous styrene–ethylene–butylene–styrene (SEBS)‐based breathable triboelectric sensor is newly designed and fabricated for increasing user comfort and reliability. The reliability of the fabricated sensor is evaluated by measuring the heat dissipation through the skin–sensor interface using a thermal IR imaging test. Similarly, the sensor's breathability is quantified through a water vapor transmission rate (WVTR) test, where the achieved breathability of 5.88 mg cm−2 h−1 is sufficient for sweat evaporation, as an average person loses 1.2–4.2 mg cm−2 h−1 of sweat. Furthermore, a porous, metal‐free, hybridized nanoporous carbon (H‐NPC)/laser‐induced graphene (LIG) is utilized as a charge‐collecting electrode, which is transferred and conformally attached to the Siloxene/SEBS substrate. This results in a reduction in the interfacial resistance and an improvement in bonding between the dielectric and electrode layers. With a pressure sensitivity of 0.75 VkPa−1, the fabricated sensor demonstrates successful application in gesture recognition. Thus, this research showcases the considerable potential for developing triboelectric naongenerators (TENGs) with breathable and reliable features and underscores their broad applicability in human–machine interfaces and soft robotics systems.
Durable Organic Photovoltaics Enabled by a Morphology‐Stabilizing Hole‐Selective Self‐Assembled Monolayer
Authors: Wang Yiwen , Jiang Wenlin , Liu Shi‐Chun , Lin Chieh‐Ting , Fan Baobing , Li Yanxun , Gao Huanhuan , Liu Ming , Lin Francis R. , Jen Alex K.‐Y. 
Published: December 2023

AbstractOrganic photovoltaics (OPVs) have recently achieved efficiencies of over 19% and are well underway toward practical applications. However, issues concerning operational stability remain a major challenge ahead of OPV commercialization. Here, when replacing the conventional hole‐transporting layer PEDOT:PSS with a self‐assembled monolayer of [2‐(3,6‐dichloro‐9H‐carbazol‐9‐yl)ethyl]phosphonic acid (3,6‐Cl‐2PACz) or [2‐(4,5‐dichloro‐9H‐carbazol‐9‐yl)ethyl]phosphonic acid (4,5‐Cl‐2PACz) it is found that the T80 lifetime of PM6:BTP‐eC9‐based devices can be improved from ~100 to ~470 and over 800 h, respectively. The power conversion efficiency is also improved from 17.29% to 18.17% and 18.67%, respectively. The improved performance and prolonged photostability in 4,5‐Cl‐2PACz‐based devices stem from the stabilized vertical distribution of donor and acceptor components, reducing the energetic disorder and thus alleviating non‐radiative recombination losses. It is further found that the surface energy of 4,5‐Cl‐2PACz‐modified substrates stays constant under prolonged illumination due to the improved intrinsic photostability of 4,5‐Cl‐2PACz, supporting the robust active layer morphology. Applying 4,5‐Cl‐2PACz in a ternary device of PM6:BTP‐eC9:L8‐BO‐F delivered an efficiency of 19.05% and a T80 lifetime over 1140 h.
Response of yellow perch to water level fluctuations in oligotrophic, north‐temperate inland lakes
Authors: Shay Gabrielle P. , Sass Greg G. , Mrnak Joseph T. 
Published: December 2023

AbstractInformation on yellow perch Perca flavescens population dynamics and responses to various abiotic and biotic factors in oligotrophic, north‐temperate inland lakes is limited. Water level fluctuations are known to influence available habitat and biological communities within the littoral zones of lakes, yet research is lacking for yellow perch in Wisconsin. The goal of our study was to characterize yellow perch population‐level responses to natural water level fluctuations in four northern Wisconsin lakes using a 39‐year time series. On average, increasing water level periods correlated with lower mean fyke net and gill net relative abundances (catch‐per‐unit‐effort), though generally not statistically significant. Yellow perch mean relative weight varied among lakes and was significantly greater during increasing water level periods for all lakes except one. The lack of statistically significant findings potentially suggests a buffering mechanism of north‐temperate oligotrophic lakes due to their small surface area to volume ratios, relative lack of nutrients, and(or) littoral structural habitat compared to other systems (e.g., shallow eutrophic lakes). Our results suggest that natural water level fluctuations may not be an environmental concern for yellow perch populations in some north‐temperate oligotrophic inland lakes.
Harmonization of four biomarkers across nine nationally representative studies of older persons
Authors: Hu Peifeng , Crimmins Eileen M. , Kim Jung Ki , Potter Alan , Cofferen Jake , Merkin Sharon , McCreath Heather , Seeman Teresa 
Published: December 2023

AbstractIntroductionA growing number of international population surveys have included measurement of biomarkers, but differ in the type of specimens collected, sample processing procedures, shipment protocols, and laboratory assay platforms. The purpose of this study is to harmonize biomarker data from nine nationally representative studies of people 50 years of age and over by adjusting for assay platforms and type of specimens for total cholesterol (total‐C), high‐density lipoprotein cholesterol (HDL‐C), glycosylated hemoglobin (HbA1c), and C‐reactive protein (CRP).MethodsSets of 24 identical serum, plasma, whole blood, and dried blood spot harmonization samples with known analyte levels were generated at a reference laboratory, shipped at −80°C to the respective study laboratories, and subsequently assayed following the study laboratory's protocol. Both original and harmonized study data were used to calculate mean values and at‐risk prevalence.ResultsThe correlation coefficients between the biomarker values of the harmonization samples obtained by the study laboratories and the reference laboratory were 0.99 or above for all analytes and laboratories, indicating the high quality of assays at all laboratories. However, using the harmonized data from each study, there were significant differences in the mean values and country ranking of the prevalence of at‐risk levels of these four biomarkers.ConclusionsWhile the biomarker data from the different study laboratories were highly correlated, indicating very high correlation of rank order of specimens, absolute values did vary significantly. This can have a major impact on assessment of international differences in estimates of risks for chronic morbidity and mortality.
A patient with Pitt–Hopkins syndrome with concomitant common variable immunodeficiency
Authors: Malik Shahzara , Jeanpierre Latoya , Cianferoni Antonella , Ruffner Melanie , Sullivan Kathleen E. 
Published: December 2023

AbstractIn patients with 18q deletion syndrome (18q‐), immunodeficiency, autoimmunity, and allergies have been described in a subset. Pitt–Hopkins syndrome represents a specific subset of patients with 18q‐ who have a proximal deletion involving the TCF4 gene or a TCF4 variant. Immunodeficiency has been reported in the overall 18q‐ population; however, immunodeficiency with Pitt‐Hopkins syndrome has not been highlighted. This case report details the immunologic evaluations and the associated infections seen in a young adult with Pitt–Hopkins syndrome to underscore the challenges of managing adults with a complex phenotype who develop frequent infections. This patient with Pitt–Hopkins syndrome ultimately fulfilled the diagnostic criteria for common variable immunodeficiency. Immunoglobulin replacement has led to a somewhat improved infection pattern, although she continues to have aspiration events leading to pneumonia. This case highlights the clinical evolution of Pitt–Hopkins syndrome and serves as a reminder that immunodeficiency can occur in this syndrome.
Genetic counselors' utilization of ChatGPT in professional practice: A cross‐sectional study
Authors: Ahimaz Priyanka , Bergner Amanda L. , Florido Michelle E. , Harkavy Nina , Bhattacharyya Sriya 
Published: December 2023

AbstractPurposeThe precision medicine era has seen increased utilization of artificial intelligence (AI) in the field of genetics. We sought to explore the ways that genetic counselors (GCs) currently use the publicly accessible AI tool Chat Generative Pre‐trained Transformer (ChatGPT) in their work.MethodsGCs in North America were surveyed about how ChatGPT is used in different aspects of their work. Descriptive statistics were reported through frequencies and means.ResultsOf 118 GCs who completed the survey, 33.8% (40) reported using ChatGPT in their work; 47.5% (19) use it in clinical practice, 35% (14) use it in education, and 32.5% (13) use it in research. Most GCs (62.7%; 74) felt that it saves time on administrative tasks but the majority (82.2%; 97) felt that a paramount challenge was the risk of obtaining incorrect information. The majority of GCs not using ChatGPT (58.9%; 46) felt it was not necessary for their work.ConclusionA considerable number of GCs in the field are using ChatGPT in different ways, but it is primarily helpful with tasks that involve writing. It has potential to streamline workflow issues encountered in clinical genetics, but practitioners need to be informed and uniformly trained about its limitations.
Development and validation of a computable phenotype for Turner syndrome utilizing electronic health records from a national pediatric network
Authors: Huang Sarah D. , Bamba Vaneeta , Bothwell Samantha , Fechner Patricia Y. , Furniss Anna , Ikomi Chijioke , Nahata Leena , Nokoff Natalie J. , Pyle Laura , Seyoum Helina , Davis Shanlee M. 
Published: December 2023

AbstractTurner syndrome (TS) is a genetic condition occurring in ~1 in 2000 females characterized by the complete or partial absence of the second sex chromosome. TS research faces similar challenges to many other pediatric rare disease conditions, with homogenous, single‐center, underpowered studies. Secondary data analyses utilizing electronic health record (EHR) have the potential to address these limitations; however, an algorithm to accurately identify TS cases in EHR data is needed. We developed a computable phenotype to identify patients with TS using PEDSnet, a pediatric research network. This computable phenotype was validated through chart review; true positives and negatives and false positives and negatives were used to assess accuracy at both primary and external validation sites. The optimal algorithm consisted of the following criteria: female sex, ≥1 outpatient encounter, and ≥3 encounters with a diagnosis code that maps to TS, yielding an average sensitivity of 0.97, specificity of 0.88, and C‐statistic of 0.93 across all sites. The accuracy of any estradiol prescriptions yielded an average C‐statistic of 0.91 across sites and 0.80 for transdermal and oral formulations separately. PEDSnet and computable phenotyping are powerful tools in providing large, diverse samples to pragmatically study rare pediatric conditions like TS.
Organocatalyzed Synthesis of Bicyclic γ‐Lactam Derivatives via Asymmetric Conjugate Addition of Cyclic β‐Keto Esters to Benzoyl Acrylonitriles
Authors: Matsushima Yasuyuki , Kubokawa Satsuki , Watanabe Mia , Nakashima Kosuke , Hirashima Shin‐ichi , Miura Tsuyoshi 
Published: December 2023

AbstractA diaminomethylenemalononitrile organocatalyst efficiently promoted the asymmetric conjugate addition of cyclic β‐keto esters to benzoyl acrylonitriles to afford the corresponding adducts. This was followed by the transformation of the nitrile group into an amide group, resulting in bicyclic γ‐lactam derivatives in good yields with excellent enantioselectivities (up to 99 % ee). As far as we know, this is the first study to synthesize chiral bicyclic γ‐lactam derivatives from cyclic β‐keto esters and benzoyl acrylonitriles.
One Collision—Two Substituents: Gas‐Phase Preparation of Xylenes under Single‐Collision Conditions
Authors: Medvedkov Iakov A. , Nikolayev Anatoliy A. , He Chao , Yang Zhenghai , Mebel Alexander M. , Kaiser Ralf I. 
Published: December 2023

AbstractThe fundamental reaction pathways to the simplest dialkylsubstituted aromatics—xylenes (C6H4(CH3)2)—in high‐temperature combustion flames and in low‐temperature extraterrestrial environments are still unknown, but critical to understand the chemistry and molecular mass growth processes in these extreme environments. Exploiting crossed molecular beam experiments augmented by state‐of‐the‐art electronic structure and statistical calculations, this study uncovers a previously elusive, facile gas‐phase synthesis of xylenes through an isomer‐selective reaction of 1‐propynyl (methylethynyl, CH3CC) with 2‐methyl‐1,3‐butadiene (isoprene, C5H8). The reaction dynamics are driven by a barrierless addition of the radical to the diene moiety of 2‐methyl‐1,3‐butadiene followed by extensive isomerization (hydrogen shifts, cyclization) prior to unimolecular decomposition accompanied by aromatization via atomic hydrogen loss. This overall exoergic reaction affords a preparation of xylenes not only in high‐temperature environments such as in combustion flames and around circumstellar envelopes of carbon‐rich Asymptotic Giant Branch (AGB) stars, but also in low‐temperature cold molecular clouds (10 K) and in hydrocarbon‐rich atmospheres of planets and their moons such as Triton and Titan. Our study established a hitherto unknown gas‐phase route to xylenes and potentially more complex, disubstituted benzenes via a single collision event highlighting the significance of an alkyl‐substituted ethynyl‐mediated preparation of aromatic molecules in our Universe.
Rational Design and Reticulation of Infinite qbe Rod Secondary Building Units into Metal–Organic Frameworks through a Global Desymmetrization Approach for Inverse C3H8/C3H6 Separation
Authors: Gong Wei , Xie Yi , Yamano Akihito , Ito Sho , Reinheimer Eric W. , Dong Jinqiao , Malliakas Christos D. , Proserpio Davide M. , Cui Yong , Farha Omar K. 
Published: December 2023

AbstractThe development of reticular chemistry has enabled the construction of a large array of metal–organic frameworks (MOFs) with diverse net topologies and functions. However, dominating this class of materials are those built from discrete/finite secondary building units (SBUs), yet the designed synthesis of frameworks involving infinite rod‐shaped SBUs remain underdeveloped. Here, by virtue of a global linker desymmetrization approach, we successfully targeted a novel Cu‐MOF (Cu‐ASY) incorporating infinite Cu‐carboxylate rod SBUs with its structure determined by micro electron diffraction (MicroED) crystallography. Interestingly, the rod SBU can be simplified as a unique cylindric sphere packing qbe tubule made of [43.62] tiles, which further connect the tritopic linkers to give a newly discovered 3,5‐connected gfc net. Cu‐ASY is a permanent ultramicroporous material featuring 1D channels with highly inert surfaces and shows a preferential adsorption of propane (C3H8) over propene (C3H6). The efficiency of C3H8 selective Cu‐ASY is validated by multicycle breakthrough experiments, giving C3H6 productivity of 2.2 L/kg. Density functional theory (DFT) calculations reveal that C3H8 molecules form multiple C−H⋅⋅⋅π and atypical C−H⋅⋅⋅ H−C van der Waals interactions with the inner nonpolar surfaces. This work therefore highlights the linker desymmetrization as an encouraging and intriguing strategy for achieving unique MOF structures and properties.
Evaluation of the influence of adding clay in polymeric hydrogels based on partially hydrolyzed polyacrylamide and aluminum citrate
Authors: Neto Venâncio J. S. , Dores Felipe G. L. , Oliveira Priscila F. , Mansur Claudia R. E. 
Published: December 2023

AbstractPolymeric hydrogels have been evaluated for their ability to block high‐permeability regions of heterogeneous reservoirs, distributing the injected fluids to low‐permeability regions, aiming to improve oil recovery. However, the stability of these hydrogels can be reduced under conditions of high temperature and salinity typical of reservoirs. Thus, the objective of this study was to assess the properties of hydrogels based on partially hydrolyzed polyacrylamide, with different molar masses, crosslinked with aluminum citrate, in the presence or absence of bentonite clay. We call these systems composite hydrogels or conventional hydrogels, respectively, and prepared them in synthetic brine containing 29,940 mg/L of total dissolved solids. The selected hydrogels were submitted to rheology tests and scanning electron microscopy for assignment of gel strength codes. The results showed it was possible to obtain composite hydrogels with enhanced thermal properties in comparison with conventional hydrogels, mainly at a temperature of 85°C. The rheological tests, by determining the viscous modulus (G"), elastic modulus (G'), and the ratio between the two (G"/G'), along with the tan δ factor, indicated competition in the interaction between the clay and crosslinker, due to the latter's positive charges in relation to the negative charges present in the polymer chains. The scanning electron microscopy micrographs showed the presence of clay particles adhered in the polymer chain, improving the thermal resistance of the system.
Reconfigurable and Phase‐Engineered Acoustic Metasurfaces for Broadband Wavefront Manipulation
Authors: Zeng Kexin , Li Zhendong , Guo Zichao , Wang Zhonggang 
Published: December 2023

AbstractA novel type of phase‐engineered acoustic metasurfaces with reconfigurable properties is reported, enabling the flexible broadband manipulation of reflected wavefronts. The participants of the metasurface are elements conceived to possess even‐distributed reflected phases covering 2π span with linearity and small acoustic energy loss. The reconfigurable property of the metasurface is implemented by rearranging the fixed meta‐elements based on the phase profile, which is related to the characteristic of a specific wavefront shape. The metasurface's capability is successfully demonstrated to achieve acoustic focusing and bending within the frequency range of 2300–2800 Hz, showcasing its feasibility and adaptability. To enhance its practical applications, porous materials are incorporated, leveraging the robustness of phase differences among the meta‐elements to achieve high acoustic energy cancellation. Effective sound attenuation occurs within the frequency range of 1300–3100 Hz, even under wide‐angle incidences ranging from −80° to 80°. The work paves the way for further research on reconfigurable acoustic metasurfaces in broad frequency regions and exerts favorable implications for generally applicable structures applied in multi‐fields including biomedical acoustics, noise control, and so on.
Boosting Peroxymonosulfate Activation via CoS/MXene Nanocomposite for Rhodamine B Degradation under Simulated Sunlight Irradiation
Authors: Wu Yizhou , Zhao Qingzi , Wang Jia , Lu Sitong , Zhou Liang , Lei Juying , Zhang Jinlong , Liu Yongdi 
Published: December 2023

AbstractCobalt‐based heterogeneous catalysts have been demonstrated as an effective PMS activator for pollutant degradation. However, the limited active sites on their surface lead to an unsatisfactory catalytic efficiency. Immobilizing the catalysts on the support material can be a promising modification strategy to solve this problem. MXene has been considered as an ideal support material due to its unique morphology and physicochemical properties. Therefore, in this work, the CoS‐loaded Ti3C2 MXene (CoS/Ti3C2 MXene) catalyst for peroxymonosulfate (PMS) activation was successfully synthesized through a solvothermal method. Under the simulated sunlight irradiation, the CoS/Ti3C2 MXene+PMS system achieved an impressive efficiency in removing the organic pollutant rhodamine B (97.2 % in 10 min). Among the tested catalysts, 30 %‐CoS‐TC stood out, exhibited a broad pH tolerance from 5 to 9 and maintained robust degradation performance over cycles. Upon detailed analysis, the degradation mechanism revealed the collaborative action dominated by singlet oxygen, and supplemented by photogenerated holes and superoxide radicals in the process. Notably, the sandwich‐like structure of MXene played a pivotal role, not only dispersing the CoS particles evenly on the surface of catalysts, but also providing ample space for the active sites, thus accelerating the PMS activation for the degradation of rhodamine B. Overall, this study developed an innovative MXene‐based catalyst for the application of environmental remediation.
A geometric key for enhancing the radiative efficiency of ortho‐carboranyl luminophores: Indolocarbazole‐ and m‐terphenyl‐ortho‐carboranes
Authors: Kim Mingi , Cho Kanghee , Seo Yung Ju , Choi Junhyeok , Kim Namkyun , Shin Ilsup , Lee Kang Mun 
Published: December 2023

AbstractIn this study, we introduce two ortho‐carboranyl compounds, namely ICzCB and mTPCB, which exhibit different planarity in their appended π‐conjugated aromatic groups, to investigate the influence of geometric effects on the regulation of the radiative efficiency. Both the compounds are fully characterized, revealing distinct geometric differences (planarity) in their single‐crystal structures. While ICzCB presents strong ICT‐based emission in the solid (film) state, mTPCB displays dual emission in the high‐ and low‐energy regions that originates from locally excited (LE)‐ and ICT‐based processes, respectively. Quantitative analysis of the photophysical characteristics of the compounds shows that the ICT‐based radiative efficiency in ICzCB is higher than that in mTPCB. Consequently, these findings demonstrate that the planarity of the π‐conjugated aryl group appended on o‐carborane, which is represented by planar ICzCB and distorted mTPCB, is an important key to control the ICT‐based radiative decay efficiency.