bluuebunny/crossref_metadata_2025_split huggingface dataset:
A synthesis of post‐esterified oxidized starch accompanied with physicochemical property analysis and esterification reaction condition optimization
Authors: Jiang Linxu , Zhang Wenxin , Fang Ke , Wang Honglong , Wang Xiaoguang , Su Xiaoya , Xia Faming 
Published: October 2023

AbstractEsterification is a normal method for starch modification while reaction condition is not clear. Here, pure corn starch and vinyl acetate were chosen for starch esterification. Reaction conditions involving esterifying agent content, pH, reaction time and temperature were explored. Dess‐Martin periodinane (DMP) pretreatment was adopted to accelerate esterification. Main results reveal that a content of 30 wt% vinyl acetate, pH = 9, time as 1 h and temperature as 45°C is an optimized condition for vinyl acetate esterification and DMP oxidization can enhance it. After modification, variations in microstructure, surface morphology and macroscopic properties such as viscosity, transparency, adhesion property were explored by FT‐IR, XRD, SEM, TGA, UV–Vis, viscosity, and slushing experiments. Main results reveal that after esterification carbonyl groups were introduced, lattice plane occurred expansion, surface morphology was destroyed, water absorption capacity, viscosity, and gelatinization temperature decreased while transparency, thermal‐stability and adhesion property increased. DMP treatment enhanced the previous variations. It seems via a middle‐level DMP pretreatment and vinyl acetate esterification starch solution viscosity and gelatinization temperature decreased greatly while transparency and adhesion force increased greatly, possibly having a potential use in textile industry. For instance, using as slurry its manufacture cost can be decreased with decreased energy consumption, economical.
Neuroprotective effect of biogenically synthesized ZnO nanoparticles against oxidative stress and β‐amyloid toxicity in transgenic Caenorhabditis elegans
Authors: Mani Renuka , Ezhumalai Dhineshkumar , Muthusamy Ganesan , Namasivayam Elangovan 
Published: October 2023

AbstractAmyloid β (Aβ) plaque accumulation‐mediated neuronal toxicity has been suggested to cause synaptic damage and consequent degeneration of brain cells in Alzheimer's disease (AD). With the increasing prerequisite of eco‐friendly nanoparticles (NPs), research investigators are utilizing green approaches for the synthesis of zinc oxide (ZnO) NPs for pharmaceutical applications. In this present study, ZnO NPs were synthesized from Acanthus ilicifolius to assess the neuroprotective properties in the AD model of transgenic Caenorhabditis elegans strains CL2006 and CL4176 expressing Aβ aggregation. Our findings revealed that the therapeutic effect of green‐synthesized ZnO NPs is associated with antioxidant activity. We also found that ZnO NPs significantly enhance the C. elegan's lifespan, locomotion, pharyngeal pumping, chemotaxis behavior also diminish the ROS deposition and intracellular productionMoreover, thioflavin T staining demonstrated that ZnO NPs substantially attenuated the Aβ deposition in the C. elegans strain as compared to untreated worms. With their antioxidant properties, the greenly synthesized ZnO NPs had a significant neuroprotective efficiency on Aβ‐induced toxicity by reducing Aβ aggregation and specifically reducing the progression of paralysis in the C. elegans AD model. Our findings suggested that the biosynthesized ZnO NPs could be thought‐provoking candidates for age‐associated neurodegenerative disorders accompanied by oxidative stress.
Katalytische Erscheinungen an Aerosolen
Authors: Bartholomé E. , Sachsse H. 
Published: October 2023

AbstractUntersuchung des Wechselspiels von Koagulation und chemischer Reaktion an Aerosolen am Beispiel von Ruß in Flammengasen: Scheinbare Beschleunigung der Reaktion von Ruß mit Wasserdampf durch feste nickelhaltige Kontakte, Nachweis, daß nicht der feste Kontakt katalytisch wirkt, sondern Nickeldampf, der vom Kontakt ins Gas geliefert wird. Katalytische Beeinflussung der gleichen Reaktion durch verschiedene Salze, die in kolloidverteiltem Zustand den Flammengasen zugesetzt wurden und deren Wirkung vermutlich auf einer Behinderung der Koagulation der Rußteilchen beruht.
Zur Kinetik der Bildung Schiffscher Basen I. Mitt.: Säurekatalysierte Reaktion von p‐Nitrobenzaldehyd mit p‐Dimethylaminoanilin
Authors: Kresze Günter , Manthey Hubertus 
Published: October 2023

AbstractDie Kinetik der oben genannten Reaktion in Methanol wird bei konstanter Ionenstärke und in gepufferten Lösungen durch colorimetrische Messungen untersucht. Die Reaktion unterliegt danach spezifischer Oxoniumionenkatalyse, sie besitzt eine große negative Aktivierungsentropie und eine kleine Aktivierungsenergie. Der Salzeffekt ist positiv. Die Ergebnisse werden im Rahmen des allgemeinen Mechanismus für Kondensationsreaktionen von Carbonylverbindungen mit Stickstoffverbindungen zu deuten versucht.
Über den Einfluß der Gasatmosphäre und des Preßdrucks auf Reaktionen im festen Zustand
Authors: Henrich Günter 
Published: October 2023

AbstractZur Untersuchung des Einflusses von Fremdgasen und Kontaktmöglichkeiten auf die Reaktionsgeschwindigkeiten fester Substanzen wird eine Apparatur beschrieben, in der der zeitliche Verlauf von Reaktionen im festen Zustand in definierten Gasatmosphären verfolgt werden kann. Hiermit wurde die Temperaturabhängigkeit einer Reihe von Spinellreaktionen in Stickstoff sowie der Einfluß des Preßdrucks, der Korngröße, des Vermischungsgrades verschiedener Fremdgase (O2, H2, CO2, SO2 und NH3) und des Vakuums auf die Reaktionsgeschwindigkeit untersucht.Der Preßdruck wirkt in drei deutlich voneinander verschiedenen Effekten ein, die sich zum Teil überlagern. Die Korngröße (des Al2O3) beeinflußt im System ZnO/Al2O3 die Reaktionsgeschwindigkeit praktisch nicht. O2 fördert die Reaktion MgO + Cr2O3 schon in geringen Spuren sehr stark, was durch eine intermediäre MgCrO4‐Bildung erklärt wird. Während O2 im System MgO/Al2O3 ohne Wirkung ist, wird die Reaktion MgO + Fe2O3 durch O2 merklich gehemmt, wofür die Zurückdrängung der thermischen Dissoziation des Fe2O3 verantwortlich gemacht werden kann. H2 und NH3 üben im System MgO/Al2O3 keinen Einfluß aus. Während im System MgO/Al2O3 CO2 ohne sichtbare Wirkung ist, beschleunigt dieselbe Gasatmosphäre im System ZnO/Al2O3 die Reaktionsgeschwindigkeit merklich. SO2 erhöht den Umsatz im System MgO/Al2O3 beträchtlich. Für eine Änderung der Reaktionsgeschwindigkeit im Vakuum konnte kein eindeutiger Beweis erbracht werden.
Zur Temperaturabhängigkeit der Dielektrizitätskonstante von Ammonium‐ und Kaliumchromalaunen
Authors: Wohofsky O. 
Published: October 2023

AbstractAn Ammonium‐ und Kaliumchromalaunen sowie an deren Mischkristallen wurde die Temperaturabhängigkeit der Dielektrizitätskonstante gemessen. Aus Einkristallen wurden Plattenkondensatoren hergestellt, deren Kapazität mit einem Kapazitätsmeßgerät von Rhode und Schwarz bestimmt wurde. Beim NH4Cr‐Alaun steigt die DK von 6,5 bei Zimmertemperatur beim Abkühlen sehr stark an und durchläuft bei 83 °K ein scharfes Maximum (ϵ = 12). Beim Wiedererwärmen tritt thermische Hysterese von etwa 10 grd Breite auf. Bei den Mischkristallen verschwindet die Temperaturabhängigkeit mit zunehmendem Kaliumgehalt rasch. Beim reinen KCr‐Alaun ist die DK bis zu 25 °K nahezu temperaturunabhängig. Die starke Temperaturabhängigkeit der DK des Ammoniumchromalaun läßt sich durch Orientierungspolarisation deuten.
Dynamische Untersuchungen an der Phasengrenze Germanium‐Elektrolyt. Mitteilung II: Ein spezielles Polarisationsverfahren zur Untersuchung von Halbleiterelektroden
Authors: Gobrecht H. , Schaldach M. , Hein F. , Blaser R. , Wagemann H.‐G. 
Published: October 2023

AbstractDas Elektrodenpotential einer Halbleiterelektrode setzt sich aus der Bandverbiegung ϕs und dem Spannungsabfall im Elektrolyten VH zusammen. Durch ein besonderes Polarisationsverfahren gelingt es, diese beiden Anteile mit Hilfe schneller Kapazitätsmessungen zu trennen. Auf diese Weise wird es möglich, die Kinetik der Umwandlung der elektrochemischen Doppelschicht an der Phasengrenze Halbleiter‐Elektrolyt genauer zu untersuchen. Insbesondere ergeben sich für Germaniumelektroden mehrere stabile Strukturen, die unterschiedlichen Oxydationszuständen der Oberfläche entsprechen. Die Zugabe von Kupferionen zum Elektrolyten hat keine Zusatzkapazität im Sinne der Umladung von diskreten Oberflächenzuständen zur Folge, sondern bewirkt lediglich eine Änderung in der Umwandlungskinetik.
Attaining Sustainable Development Goals through embedding circular economy principles: Evidence from food processing small‐ and medium‐sized enterprises in India
Authors: Ghosh Sudipta , Raut Rakesh D. , Cheikhrouhou Naoufel , Sinha Sudipta , Ray Amitava 
Published: October 2023

AbstractVarious industries are gradually sifting away from the linear economy and toward the circular economy (CE), but its advancement is crawling far behind the environmental contamination by the food processing industry in developing countries. Hardly any research analyzes the CE performance of food processing small‐ and medium‐sized enterprises (FPSMEs) in an emerging economy context. Hence, developing a CE performance evaluation framework is imperative to facilitate this transition. This research proposes a comprehensive framework for evaluating CE performance based on three real‐world cases of Indian FPSMEs. Initially, 15 essential criteria are shortlisted from the literature and refined by the experts. Afterward, data are collected through questionnaires administered to experts and structured interviews. Next, this research employs a multi‐criteria decision‐making (MCDM)–based approach, in which the Criteria Importance Through Inter‐criteria Correlation (CRITIC) method is used to compute the objective weights of criteria and the Vlse Kriterijumska Optimizacija Kompromisno Resenje (VIKOR) method is used to determine the performances of FPSMEs and rank them accordingly. The results reveal that “investment in Corporate Social Responsibility (CSR),” “use of renewable energy,” “increase in scrap recycling rate,” “total
emission,” and “total water consumption” are the top five criteria for CE performance. Investment in CSR emerges as the most influential criterion for strategic corporate transformation, which blends the notions of CE and CSR as a feasible solution for designing circular business processes.
Molecular Docking and Dynamics Simulations of Ammi visnaga L. Constituents as Antimelanogenic, Anti‐Inflammatory and Anticoagulant Agents
Authors: Çatıkkaş Berna , Karacan Nurcan 
Published: October 2023

AbstractIn this study, anti‐melanogenic, anti‐inflammatory and anti‐coagulant potentials of eighteen selected constituents of Ammi visnaga L. were investigated by Induced Fit Docking (IFD) and molecular dynamic simulation with Schrödinger software. The binding free energies of the selected natural compounds were computed by means of ΔG MM‐GBSA studies. Anti‐melanogetic activity of the constituent against agaricus bisporus tyrosinase, Priestia megaterium tyrosinase and Homo sapiens tyrosinase were evaluated. The result showed that apiumetin had more negative binding free energy against three tyrosinase enzymes than cognate ligands, tropolone and kojic acid. Docking analysis was also performed to predict the constituents with anti‐inflammatory activity against human Tumor necrosis factor, Cyclooxygenase‐2, Prostaglandin D2 11‐ketoreductase AKR1C3 and Prostaglandin reductase PTGR2. The results showed that pyranocoumarins (visnadin, dihydrosamidin, samidin) have more negative binding free energy against Cyclooxygenase‐2 and Prostaglandin D2 11‐ketoreductase receptors than cognate drugs, rofecoxib and indomethacin. In addition, docking analysis shows that pyranocoumarins, apiumetin and cimifugin have more negative binding free energy against Vitamin K epoxide reductase than S‐warfarin drug, predicting that they have anticoagulant activity. Furthermore, the constituents and their cognate drugs were subjected to 100 ns MD Simulation to predict their stability at the active sites of the enzymes.
Curcuminoid Nanovesicles as Advanced Therapeutics
Authors: Abbo Hanna S. , Yufanyi Divine M. , Shah Tariq , Khaligh Nader G. , Chinnam Sampath , Efferth Thomas , Titinchi Salam J. J. 
Published: October 2023

AbstractTurmeric (Curcuma longa rhizome) is well‐known for its therapeutic properties in traditional Indian and Chinese medicines. It has preventive and therapeutic activity against diseases that target human body systems as well as various cancer types. This review focuses on the mechanism of action of curcumin against various factors involved in the metastatic process. The antimicrobial, antidiabetic, anti‐oxidant, and anti‐HIV activities and mechanism of curcumin‐functionalized nanovesicles are also reviewed. Despite the biocompatibility of curcumins, its medical applications are limited due to its low bioavailability, insolubility in water, and degradation at certain pH levels. Moreover, the low stability and rapid metabolism of curcumin limits its clinical applications. Therefore, it is imperative to design strategies to mitigate this shortfall which include the synthesis of curcumin glycosides or the development of curcumin delivery systems to improve the bioavailability and therapeutic efficacy of curcumin. This review provides insight into the different chemical methods for the synthesis and modification adopted to achieve these compounds.
Spindle cell lipoma of the tongue: First case report from the Gulf region and review of the literature
Authors: Mousa Ahmed Hafez , Nukaly Houriah Yasir , Mohamed Rawan Elwalid Ali , AlShehabi Nagam , Daoud Rabbani Mahmoud , Alsayed Abdelrahman Waleed , Roble Ramla Mohamed Farah , Mehtiyeva Nigar , Ennab Farah , Alklani Temaa , Khaled Islam 
Published: October 2023

Key Clinical MessageSpindle cell lipoma is a histological variant of oral lipomas. In this report, we present the first case from the Gulf region with the most comprehensive literature review. Clinicians should consider rare tumors in the differential diagnoses of oral masses.
Promiscuity and Selectivity of Hydroxysteroid Dehydrogenases in the Biocatalyzed Reduction of 1,2‐Diketones
Authors: Tognoli Chiara , Bertuletti Susanna , Patti Stefania , Ferrandi Erica Elisa , Vanoni Marta , Riva Sergio , Bassanini Ivan , Monti Daniela 
Published: October 2023

AbstractHydroxysteroid dehydrogenases (HSDHs) are NAD(P)H‐dependent alcohol dehydrogenases (ADHs) known for their exceptional stereo‐ and regioselectivity when acting on natural substrates, including neutral steroids, bile acids, and various steroid derivatives. Notably, in recent studies this specific subfamily of oxidoreductases has displayed intriguing substrate promiscuity, exhibiting the capacity to accommodate a diverse array of substrates, such as sterically hindered ketones and even α‐keto esters. Herein, the promiscuous nature of HSDHs was further explored by investigating their catalytic activity with representative 1,2‐diketones. This set encompasses symmetric aliphatic/aromatic diketones – namely, 3,4‐hexandione and benzil – as well as the asymmetric synthon 1‐phenyl‐1,2‐propanedione. In the case of 3,4‐hexandione, substrate conversion and selectivity closely resembled that previously observed with aliphatic α‐keto esters. On the contrary, a more heterogeneous behavior was observed in the case of aromatic substrates, with diverse performances in terms of conversions and stereo‐ or regioselectivity. Additionally, docking studies were carried out to get a deeper insight in the stereochemistry of 1,2‐diketones reduction catalyzed by the broad substrate scope and steroid‐active ketoreductase Is2‐SDR.
Free‐form reinforced concrete, prestressed concrete, and composite components: Calculation of cross‐section values
Authors: Zimmert Florian , Braml Thomas 
Published: October 2023

AbstractA resource‐efficient use of concrete as a construction material can be achieved by adapting the individual shape of a component under consideration to the stresses that occur and by arranging composite construction materials (e.g., reinforcing steel, prestressing steel, or structural steel) in suitable areas of the component. Due to the advancing digitalization in the construction industry, for example in the context of Building Information Modeling, computer‐aided 3D modeling methods are increasingly being used in the planning of structures. These allow engineers to design components in free form. In reinforced concrete, prestressed concrete, and composite construction, the design of such components is currently still associated with great effort. In the context of the development of a practical method for the calculation of free‐form concrete components, this paper presents a CAD‐integrated method for the calculation of cross‐section values. Cross‐section values are required as an essential calculation basis when real, three‐dimensional structural components are treated using simplified calculation theories, such as the beam theory. In this paper, the mathematical and numerical fundamentals of a method for the calculation of cross‐section values of free‐form concrete, reinforced concrete, prestressed concrete, and compound components are presented. The calculation method is based on flat geometric regions described by Non‐uniform Rational B‐Spline tensor product surfaces, which can be extracted from solid models, for example.
A Mitochondria‐Targeted Fluorescent and Colorimetric Probe for Sulfur Dioxide Derivatives and Hydrogen Peroxide in Live Cells
Authors: Zhou Wanting , Zhang Peng , Tang Fuyan , Shu Wei , Li Dongpeng , Zhang Xiaolei , Liu Yuying , Xiao Haibin 
Published: October 2023

AbstractThe abnormal fluctuations of sulfur dioxide (SO2) and its derivatives are closely associated with various physiological and pathological progresses in biological systems. Herein, we have developed two fluorescent and colorimetric probes based on a hemicyanine dye for the detection of SO2 derivatives and hydrogen peroxide (H2O2) in vitro and live cells. The response mechanisms involve an SO2‐derivative‐mediated nucleophilic addition reaction to the double bond and subsequent H2O2‐promoted elimination of bisulfite. As well as having excellent photophysical properties, the probe with higher fluorescence efficiency is further applied for live cell imaging, and it is found that it can solely accumulate in mitochondria and track SO2 derivatives and H2O2 in live cells.
Assessing the occurrence and severity of pre‐ and postendodontic pain in anemic and healthy female patients
Authors: Kazemipoor Maryam , Moradi Hooman , Mokhtari Fatemeh , Kheirollahi Khatereh 
Published: October 2023

AbstractObjectivesThe objective of this current survey was to assess both the occurrence and severity of pre‐ and post‐endodontic pain among female individuals, distinguishing between those with anemia and those without.Materials and MethodsIn the current study, we included a total of 60 women with anemia (hemoglobin < 11) and those without anemia (hemoglobin > 13). We recorded the occurrence and severity of pain before and at 24, 48, and 72 h following root canal treatment using a visual analog scale (VAS) ranging from 0 to 10. Additionally, we collected data on patient age, tooth type, as well as pulpal and periapical conditions. Statistical analysis was carried out using two‐way ANOVA, pairedt‐tests, and Pearson correlation coefficient. The significance level for statistical tests was set at p ≤ .05.ResultsThe incidence of preoperative pain in both anemic and non‐anemic patients was 80%. The total incidence of post‐operative pain was recorded as 71.7% (82.2% in anemic and 61.1% in non‐anemic women). Compared with the pretreatment pain incidence and intensity, the values increased in 24 h but declined in 48 h and 72 h after treatment. Considering the posttreatment pain intensity, the mean values were higher in the three time intervals (24, 48, and 72 h) in anemic patients. Pulpal and periapical status, in contrast to age and tooth type, significantly contributed to the intensity of posttreatment pain.ConclusionRegarding the importance of pain phenomenon in human life, it is recommended to consider anemia as an important risk factor for post‐endodontic pain. Early diagnosis and analgesic treatment interventions in anemic females, alongside the pain control during root canal treatment, could promote the patient's satisfaction and quality of care.
Impaired breakdown of Herwig's epithelial root sheath disturbs tooth root development
Authors: Jeong Ju‐Kyung , Kim Tak‐Heun , Choi Hwajung , Cho Eui‐Sic 
Published: October 2023

AbstractBackgroundWnt/β‐catenin signaling plays a variety of roles in both the dental epithelium and mesenchyme at most stages of tooth development. In this study, we verified the roles of Hertwig's epithelial root sheath (HERS) breakdown in tooth root development. This breakdown results in formation of epithelial cell rests of Malassez (ERM).ResultsFollowing induction of β‐catenin stabilization in the epithelium of developing tooth at the moment of HERS breakdown, HERS failed to break down for ERM formation. HERS with stabilized β‐catenin was altered into a multicellular layer enveloping elongated root dentin with higher expression of junctional proteins such as Zo‐1 and E‐cadherin. Importantly, this impairment of HERS breakdown led to arrest of further root elongation. In addition, the portion of root dentin enveloped by the undissociated HERS remained in a hypomineralized state. The odontoblasts showed ectopically higher expression of pyrophosphate regulators including Ank and Npp1, whereas Tnap expression was unchanged.ConclusionsOur data suggest that Wnt/β‐catenin signaling is decreased in HERS for ERM formation during root development. Furthermore, ERM formation is important for further elongation and dentin mineralization of the tooth roots. These findings may provide new insight to understand the contribution of ERM to root formation.
A case of renal cell carcinoma with antiphospholipid syndrome treated by robot‐assisted partial nephrectomy
Authors: Tashiro Yu , Ishitoya Satoshi , Yamamoto Ryo , Sugiyama Kyohei , Takada Hideaki , Matsumoto Keiyu , Tsuchihashi Kazunari 
Published: October 2023

IntroductionAntiphospholipid syndrome is an autoimmune disease that presents with thrombus hyperplasia. Although very rare, this disease is reported to become severe after the surgical invasion and other interventions. To our knowledge, there are no reports of partial nephrectomy in patients with antiphospholipid.Case presentationA 45‐year‐old man visited our hospital for treatment of left renal cell carcinoma. He had a history of antiphospholipid syndrome and took two antithrombotic agents. We performed a robot‐assisted partial nephrectomy. We selectively ligated only the feeding branch during the procedure. Postoperatively, there were no complications, and the patient was discharged on postoperative day 10. One year after surgery, there was no worsening of antiphospholipid syndrome.ConclusionWe reported the first case of robot‐assisted partial nephrectomy for an antiphospholipid syndrome patient. Selective ligation of the renal artery might not have contributed to the severe antiphospholipid syndrome.