bluuebunny/crossref_metadata_2025_split huggingface dataset:
Advances and opportunities in unraveling cold‐tolerance mechanisms in the world's primary staple food crops
Authors: Jan Sofora , Rustgi Sachin , Barmukh Rutwik , Shikari Asif B. , Leske Brenton , Bekuma Amanuel , Sharma Darshan , Ma Wujun , Kumar Upendra , Kumar Uttam , Bohra Abhishek , Varshney Rajeev K. , Mir Reyazul Rouf 
Published: November 2023

AbstractTemperatures below or above optimal growth conditions are among the major stressors affecting productivity, end‐use quality, and distribution of key staple crops including rice (Oryza sativa), wheat (Triticum aestivum), and maize (Zea mays L.). Among temperature stresses, cold stress induces cellular changes that cause oxidative stress and slowdown metabolism, limit growth, and ultimately reduce crop productivity. Perception of cold stress by plant cells leads to the activation of cold‐responsive transcription factors and downstream genes, which ultimately impart cold tolerance. The response triggered in crops to cold stress includes gene expression/suppression, the accumulation of sugars upon chilling, and signaling molecules, among others. Much of the information on the effects of cold stress on perception, signal transduction, gene expression, and plant metabolism are available in the model plant Arabidopsis but somewhat lacking in major crops. Hence, a complete understanding of the molecular mechanisms by which staple crops respond to cold stress remain largely unknown. Here, we make an effort to elaborate on the molecular mechanisms employed in response to low‐temperature stress. We summarize the effects of cold stress on the growth and development of these crops, the mechanism of cold perception, and the role of various sensors and transducers in cold signaling. We discuss the progress in cold tolerance research at the genome, transcriptome, proteome, and metabolome levels and highlight how these findings provide opportunities for designing cold‐tolerant crops for the future.
Characterization of the CMS genetic regulation through comparative complete mitochondrial genome sequencing in Nicotiana tabacum
Authors: He Dongli , Li Yifan , Yuan Cheng , Pei Xiaoxiong , Damaris Rebecca N. , Yu Haiqin , Qian Bao , Liu Yong , Yi Bin , Huang Changjun , Zeng Jianmin 
Published: November 2023

AbstractMitochondrial genomes (mitogenomes) of flowering plants vary greatly in structure and size, which can lead to frequent gene mutation, rearrangement, or recombination, then result in the cytoplasmic male sterile (CMS) mutants. In tobacco (Nicotiana tabacum), suaCMS lines are widely used in heterosis breeding; however, the related genetic regulations are not very clear. In this study, the cytological observation indicated that the pollen abortion of tobacco suaCMS(HD) occurred at the very early stage of the stamen primordia differentiation. In this study, the complete mitochondrial genomes of suaCMS(HD) and its maintainer HD were sequenced using the PacBio and Illumina Hiseq technology. The total length of the assembled mitogenomes of suaCMS(HD) and HD was 494,317 bp and 430,694 bp, respectively. Comparative analysis indicated that the expanded 64 K bases in suaCMS(HD) were mainly located in noncoding regions, and 23 and 21 big syntenic blocks (>5000 bp) were found in suaCMS(HD) and HD with a series of repeats. Electron transport chain‐related genes were highly conserved in two mitogenomes, except five genes (ATP4, ATP6, COX2, CcmFC, and SDH3) with substantial substitutions. Three suaCMS(HD)‐specific genes, orf261, orf291, and orf433, were screened. Sequence analysis and RT‐PCR verification showed that they were unique to suaCMS(HD). Further gene location analysis and protein property prediction indicated that all the three genes were likely candidates for suaCMS(HD). This study provides new insight into understanding the suaCMS mechanism and is useful for improving tobacco breeding.
Exploring the interplay between PARP1 and circRNA biogenesis and function
Authors: Dhahri Hejer , Fondufe‐Mittendorf Yvonne N. 
Published: November 2023

AbstractPARP1 (poly‐ADP‐ribose polymerase 1) is a multidomain protein with a flexible and self‐folding structure that allows it to interact with a wide range of biomolecules, including nucleic acids and target proteins. PARP1 interacts with its target molecules either covalently via PARylation or non‐covalently through its PAR moieties induced by auto‐PARylation. These diverse interactions allow PARP1 to participate in complex regulatory circuits and cellular functions. Although the most studied PARP1‐mediated functions are associated with DNA repair and cellular stress response, subsequent discoveries have revealed additional biological functions. Based on these findings, PARP1 is now recognized as a major modulator of gene expression. Several discoveries show that this multifunctional protein has been intimately connected to several steps of mRNA biogenesis, from transcription initiation to mRNA splicing, polyadenylation, export, and translation of mRNA to proteins. Nevertheless, our understanding of PARP1's involvement in the biogenesis of both coding and noncoding RNA, notably circular RNA (circRNA), remains restricted. In this review, we outline the possible roles of PARP1 in circRNA biogenesis. A full examination of the regulatory roles of PARP1 in nuclear processes with an emphasis on circRNA may reveal new avenues to control dysregulation implicated in the pathogenesis of several diseases such as neurodegenerative disorders and cancers.This article is categorized under:
RNA Interactions with Proteins and Other Molecules > Protein‐RNA Interactions: Functional Implications
Regulatory RNAs/RNAi/Riboswitches > Regulatory RNAs
RNA Processing > Splicing Regulation/Alternative Splicing
Peter Berck’s Contribution to the Environment for Development Initiative and Sustainable Development
Authors: Köhlin Gunnar , Berck Cyndi 
Published: November 2023

AbstractPeter Berck made major contributions to the Environment for Development Initiative (EfD). This Swedish-based initiative brings together environmental economics research centers all over the Global South in pursuit of sustainable development. Funded by the Swedish International Development Cooperation Agency (Sida), it is based at the University of Gothenburg, with research institution partners in Asia, Africa, and Latin America. EfD focuses on policy-relevant research, policy engagement, and capacity development, with a vision of “Inclusive sustainable development in the Global South founded on evidence-based management of the environment, natural resources, and climate change impacts.”
Environmental Attitudes in Developing Countries in Light of COVID-19
Authors: Toledo Chantal 
Published: November 2023

AbstractEnvironmental attitudes have the potential to affect environmental behaviors, which in turn can affect action toward current and future global environmental targets. Recent large-scale surveys find that developing countries, which account for most of the growth in greenhouse gas emissions, have high levels of pro-environmental attitudes. Respondents from developing countries state that they perceive climate change as a major global threat, that climate change directly influences their voting decisions, and that they consider climate change as big a risk as COVID-19. Respondents from developing countries with lower per capita emissions, more educated respondents, and those who have been exposed to extreme weather events tend to have more pro-environmental attitudes. However, high levels of pro-environmental attitudes do not translate into high levels of environmental performance for developing countries, as measured by a comprehensive environmental performance index. Respondents report changes in individual actions to limit their effect on climate change but tend to focus on easier behavioral changes that have a relatively low environmental impact.
A Public Economist at a Public University
Authors: Berck Cyndi Spindell 
Published: November 2023

AbstractPeter Berck was a forestry economist, an environmental economist, an agricultural economist, an energy economist, and eventually a development economist. He summed it up as a “public economist.” He also loved teaching at a public university and used his position to open doors for students and colleagues. The chapters that follow illustrate the breadth of his engagement in research, teaching, and service.
Peter Berck’s Impacts on Gender Equity in Environmental Economics
Authors: McCluskey Jill J. 
Published: November 2023

AbstractPeter Berck’s research on topics in natural resources, environmental economics, and agricultural economics was impactful both in academia and in the policy realm. His research inspired its researchers and provided insights on problems in multiple sectors. Many others have discussed Peter’s research impacts. I will focus on how Peter impacted people. He built people up and inspired them, especially his students.
Recycling Behavior and Convenience
Authors: Berck Peter , Blundell Marshall , Englander Gabriel , Gold Samantha , He Yulei , Horsager Janet , Kaplan Scott , Van Dop Sears Molly , Stevens Andrew , Trachtman Carly , Taylor Rebecca , Villas-Boas Sofia B. , Berck Cyndi Spindell 
Published: November 2023

AbstractThis chapter provides a comprehensive review of the current state of California’s recycling policies. Specifically, we focus on the demand side of the recycling system and summarize some of the evidence around the efficacy of the California Department of Recycling’s (CalRecycle) deposit-refund recycling program – in conjunction with other recycling alternatives, such as curbside recycling pickup – in providing convenient recycling options to consumers. In Sect. 2, we provide some relevant background on recycling policy in California. In Sect. 3, we discuss the findings in Berck et al. (2021), which uses survey data to empirically assess who recycles and how the public defines convenience in recycling opportunities. Next, in Sect. 4, we present the main takeaways from Berck et al. (2020), which focuses on the consumer survey evidence to estimate California residents’ preferences and willingness to pay (WTP) for current beverage container recycling methods, including curbside pickup services, drop-off at government-subsidized recycling centers, and drop-off at non-subsidized centers. Finally, in Sect. 5, we discuss avenues for future research.
Challenging Conventional Wisdom in Defense and National Security
Authors: Lipow Jonathan 
Published: November 2023

AbstractOver a 20-year period, Peter Berck and Jonathan Lipow coauthored six papers that focused on defense and national security, including three that can be regarded as influential contributions. The first of the important contributions responded to the argument that conscription is a suboptimal use of human resources and showed that conscription can be more efficient than an all-volunteer army under many, and perhaps even most, circumstances. The second contended that the real appreciation of the Iraqi dinar relative to other currencies, rather than the “surge” of coalition forces to Iraq in 2008–2009, explained the defeat of the insurgency, because the insurgents depended on foreign funding. The third showed that African-Americans were far less likely to be deployed to Iraq and Afghanistan and explored various explanations for this—concluding that the most likely cause was not racial discrimination within the military but continued racial discrimination in the civilian labor market.
Hedging with a Housing Start Futures Contract
Authors: Berck Peter , Rosen Kenneth T. 
Published: November 2023

AbstractThis chapter was originally prepared in 1984 as California University Department of Agricultural and Resource Economics (CUDARE) Working Paper 321, Giannini Foundation of Agricultural Economics Working. It is posted at the eScholarship Repository, University of California. http://repositories.cdlib.org/areucb/321. It is also a Center for Real Estate and Urban Economics Working Paper, Number 84–76, March 1984.
How Is Farm Income Affected When Each Farm Has To Produce Its Own Animal Feed?
Authors: Berck Peter , Berck Cyndi Spindell , Gebreegziabher Zenebe , Teklewold Hailemariam 
Published: November 2023

AbstractOne of the questions that Peter proposed for his memorial conference was “What happens to agricultural yields when farms are relatively autarkic and use animals? For instance, how is yield affected when each farm has to produce its own animal feed? How can this help explain why African yields are so much lower than American?”
Estimating Agricultural Acreage Responses to Input Prices: Groundwater in California
Authors: Stevens Andrew W. 
Published: November 2023

AbstractWater is arguably the most important input in California agriculture, and its importance has been highlighted by recent droughts. Farmers and researchers both have long been interested in the marginal value of agricultural water and its impact on production. However, due to a patchwork of legal doctrines, historic water rights, and the absence of any reliable market for agricultural water, estimates of water’s value in California agriculture have been challenging to come by (Buck et al., 2014). However, producers in California generally have the option to pump groundwater as a source of last resort. This pumping is largely unregulated, and only recently has California’s 2014 Sustainable Groundwater Management Act begun to impact farmers’ behavior. Producers who rely on groundwater use energy (electricity or fuel) to pump water up from an underlying aquifer. Therefore, the cost structure for groundwater is straightforward: the deeper the well, the more expensive the water.
Definitorische, theoretische und methodische Grundlagen
Authors: Wan Shujun 
Published: November 2023

ZusammenfassungDieses Kapitel beschäftigt sich mit den definitorischen, theoretischen und methodischen Grundlagen der vorliegenden Studie. Dabei wird zunächst der Begriff „Argumentationsstrategie“ erklärt, bevor eine Auseinandersetzung mit der Anwendbarkeit unterschiedlicher Modelle zur Beschreibung der Argumentationsstrategien für diese Studie erfolgt. Anschließend wird die „Kontrastive Rhetorik“, die dieser Studie einen konzeptuellen Rahmen gibt, vorgestellt: Der Abschnitt 2.2.1 gibt einen Überblick über die grundlegenden Ansätze der kontrastiven Rhetorik.
Argumentationsstrategien
Authors: Wan Shujun 
Published: November 2023

ZusammenfassungBasierend auf den Ergebnissen der Datenauswertung der RST-Analyse werden in diesem Kapitel die von den chinesischen Deutschlerner/-innen und den deutschen L1-Sprecher/-innen in den argumentativen Texten eingesetzten Schreibstrategien verglichen. Dabei werden der strukturelle, der inhaltliche sowie der sprachliche Aufbau jeder Textregion analysiert. Abschnitt 5.1 befasst sich hauptsächlich mit der Konstruktion der Einleitung.
Diskussion
Authors: Wan Shujun 
Published: November 2023

ZusammenfassungIn diesem Kapitel geht es um drei Themen, die mich im Laufe der Forschung zum Nachdenken angeregt haben und die ich gerne in dieser Arbeit beleuchten möchte. Anhand dreier konkreter Beispiele beschreibt Abschnitt 6.1 die inter- und intra-individuellen Variationen, die in den CMN- und DEU-Texten entdeckt wurden. Abschnitt 6.2 befasst sich mit möglichen Faktoren, die bei den chinesischen Deutschlerner/-innen dieser Studie einen Einfluss auf das Schreiben der deutschsprachigen argumentativen Texte ausüben können.
Integration naturwissenschaftlicher und medizinischer Grundlagen im Hamburger Modellstudiengang Zahnmedizin iMED DENT
Authors: Bender Roland , Bruhn Natascha , Eisenbarth Sophie , Lemke Rüdiger , Pantke Chiara-Fabienne , Hampe Wolfgang , Schwoerer Alexander Peter 
Published: November 2023

ZusammenfassungIm Oktober 2019 startete in Hamburg mit dem Studiengang iMED DENT erstmals in Deutschland ein integrierter Modellstudiengang der Zahnmedizin. Mit diesem Studiengang werden Lehrkonzepte wie integrierte Lehre, früher Patient:innenkontakt und früher Wissenschaftsbezug, die in den vergangenen Jahren in der Humanmedizin erfolgreich getestet wurden, auf die Zahnmedizin übertragen. Der Studienabschnitt „Normalfunktion“ im ersten Jahr des Studiengangs orientiert sich im Wesentlichen am gesunden Menschen. Ein wesentliches Augenmerk wurde in diesem Abschnitt auf die Integration der naturwissenschaftlichen und medizinischen Grundlagen der Zahnmedizin sowie auf einen frühen praktischen Bezug gelegt.Aus den Erfahrungen der ersten 4 Kohorten lassen sich erste Rückschlüsse über diesen Studienabschnitt ziehen. Seine modulare Struktur sorgt im Allgemeinen für eine Straffung der Lehrinhalte, das Angebot der integrierten Lehre wird insgesamt sehr gut angenommen. So wird beispielsweise die Präsentation naturwissenschaftlicher Grundlagen im Kontext von zahnmedizinischer Relevanz von den Studierenden des Modellstudienganges deutlich positiver bewertet als die analogen Lehrangebote von Studierenden des Regelstudienganges. In ähnlicher Weise werden der integrierte Unterricht zahnmedizinischer und medizinischer Grundlagenfächer und die frühe Einbeziehung klinischer Aspekte in den Lehrevaluationen geschätzt. Die Integration naturwissenschaftlicher und medizinischer Grundlagen findet ihre Grenzen beispielsweise in der starken Praxisorientierung des Zahnmedizinstudiums, die häufig nur wenige unmittelbare Anknüpfungspunkte für nicht-zahnmedizinische Inhalte bietet. Eine iterative Abstimmung der beteiligten Fächer lässt hier eine weiter zunehmende Verzahnung der Lehrinhalte erwarten.
Rezidivierende E.-coli-Meningitis in der Neonatalperiode
Authors: Dierl Alexander , Hanslik Gregor 
Published: November 2023

Zusammenfassung
Hintergrund
Aufgrund einer heterogenen Datenlage, kleiner Fallstudien und unterschiedlicher klinischer Konstellationen ist eine generell gültige Aussage über die Dauer einer antibakteriellen Therapie bei neonataler Meningitis schwierig. Einzelne Erfahrungsberichte können hier in der Entscheidungsfindung zur Optimierung der antibakteriellen Therapie hilfreich sein.

Ziel der Arbeit
In dieser Arbeit wird von einem weiblichen Frühgeborenen mit rezidivierenden Episoden einer neonatalen Meningitis nach initialer Sepsis mit E. coli berichtet. Mögliche Risikofaktoren und Optimierungspunkte der Therapie sowie verschiedene diagnostische Optionen zum Ausschluss anatomischer oder immunologischer Risikofaktoren werden dargelegt.

Material und Methoden
Fallbericht über ein weibliches Frühgeborenes der 35 + 3 Schwangerschaftswoche mit 3 Episoden einer Escherichia-coli(E. coli)-Meningitis.

Ergebnisse
In unserem Fall war eine Anwendungsdauer von 6 Wochen zur erfolgreichen Infektionstherapie notwendig. Es lagen weder eine anatomische Anomalie noch ein Immundefekt als Risikofaktor für die 3 Episoden einer E.-coli-Meningitis mit Sepsis vor. In den Magnetresonanztomographie (MRT)- und Positronenemissionstomographie/Computertomographie (PET-CT)-Untersuchungen sowie in wiederholten Ultraschalluntersuchungen konnte die Diagnose bildmorphologisch dargestellt werden.

Diskussion
Die optimale Therapiedauer bei neonataler Meningitis muss auch weiterhin anhand der patientenbezogenen Risikofaktoren sowie des Ergebnisses der mikrobiellen Untersuchung gewählt werden. In unserem Fall konnte der auslösende Erreger (E. coli) als maßgeblicher Risikofaktor für die rezidivierende Meningitis und die Notwendigkeit einer prolongierten antibakteriellen Therapie eruiert werden.
Limited evidence in support of bone marrow aspirate concentrate as an additive to the bone marrow stimulation for osteochondral lesions of the talus: a systematic review and meta‐analysis
Authors: Klein Chiel , Dahmen Jari , Emanuel Kaj S. , Stufkens Sjoerd , Kerkhoffs Gino M. M. J. 
Published: November 2023

AbstractPurposeBone marrow aspirate concentrate can be used as an additive to surgical treatment of osteochondral lesions of the talus. This systematic literature review aims to study the effect of the additional use of bone marrow aspirate concentrate on top of a surgical treatment for osteochondral lesions of the talus on clinical outcomes compared to surgical treatment alone.MethodsAn online literature search was conducted using PubMed (Medline), Embase (Ovid), and the Cochrane library for all studies comparing a surgical intervention with bone marrow aspirate concentrate, with a surgical intervention without bone marrow aspirate concentrate. The methodological quality was rated according to the methodological index for non‐randomised studies checklist. The primary outcome measure were clinical outcomes. Secondary outcome measures consisted of revision rate, complication rate, radiographic outcome measures and histological analyses. Subgroups were created based on type of surgical intervention used in the studies. If multiple articles were included in a subgroup, a linear random‐effects model was used to compare the bone marrow aspirate concentrate‐augmented group with the control group.ResultsOut of 1006 studies found, eight studies with a total of 718 patients were included. The methodological quality, assessed according to the methodological index for non‐randomised studies checklist, was weak. A significantly better functional outcome measures (p < 0.05) was found in the subgroup treated with bone marrow stimulation + bone marrow aspirate concentrate compared to the group treated with bone marrow stimulation alone, based on three non‐blinded studies. No significant differences regarding clinical outcomes were found in the subgroups comparing matrix‐induced autologous chondrocyte implantation with matrix‐induced bone marrow aspirate concentrate, osteochondral autologous transplantation alone with osteochondral autologous transplantation + bone marrow aspirate concentrate and autologous matrix‐induced chondrogenesis plus peripheral blood concentrate vs. matrix‐associated stem cell transplantation bone marrow aspirate concentrate.ConclusionThere is insufficient evidence to support a positive effect on clinical outcomes of bone marrow aspirate concentrate as an additive to surgical treatment of osteochondral lesions of the talus. However, based on the safety reports and initial results, sufficiently powered, patient‐ and researcher‐blinded, prospective randomised controlled trials are justified and recommended. Until then, we advise not to implement a therapy (addition of bone marrow aspirate concentrate) without clinical evidence that justifies the additional costs involved.Level of evidenceLevel III.
Disentangling the Computational Complexity of Network Untangling
Authors: Froese Vincent , Kunz Pascal , Zschoche Philipp 
Published: November 2023

AbstractWe study the network untangling problem introduced by Rozenshtein et al. (Data Min. Knowl. Disc. 35(1), 213–247, 2021), which is a variant of Vertex Coveron temporal graphs–graphs whose edge set changes over discrete time steps. They introduce two problem variants. The goal is to select at mostktime intervals for each vertex such that all time-edges are covered and (depending on the problem variant) either the maximum interval length or the total sum of interval lengths is minimized. This problem has data mining applications in finding activity timelines that explain the interactions of entities in complex networks. Both variants of the problem are NP-hard. In this paper, we initiate a multivariate complexity analysis involving the following parameters: number of vertices, lifetime of the temporal graph, number of intervals per vertex, and the interval length bound. For both problem versions, we (almost) completely settle the parameterized complexity for all combinations of those four parameters, thereby delineating the border of fixed-parameter tractability.