bluuebunny/crossref_metadata_2025_split huggingface dataset:
Who benefits from criminal legal reform? A natural experiment to assess racial disparities in a policy targeting monetary sanctions
Authors: Mauri Amanda Isabel , Nicosia Nancy , Kilmer Beau 
Published: January 2024

Abstract
Objective
To examine disparities in court fines between American Indian and White convicted persons before and after a South Dakota reform, which trained court personnel to only assess fines that could be reasonably paid by defendants.

Methods
A natural experiment design using criminal records for the universe of convictions for misdemeanor arrests between July 2011–June 2015 (N = 34,700) was employed to estimate the association between the reform and the likelihood of a fine using logistic regression.

Results
The reform was associated with reductions in fine assessments in urban (OR, 0.63; CI, 0.39–1.04); rural, no Indian Country (OR, 0.24; CI, 0.18–0.33); and rural, part-Indian Country counties (OR, 0.24; CI, 0.18–0.32). Both American Indian and White persons experienced these reductions, but the reductions were smaller for American Indians in urban counties.

Conclusions
A defendant’s race and features of local court structures may shape judicial behavior in response to monetary sanctioning reforms.
Towards developing a control of grinding processes using a combination of grinding power evaluation and Barkhausen noise analysis
Authors: Jedamski Rahel , Kuhlmann Gerrit , Rößler Maximilian , Karpuschewski Bernhard , Dix Martin , Epp Jérémy 
Published: January 2024

AbstractAfter grinding of hardened workpieces, especially in case of safety-relevant components, usually non-destructive testing is carried out to detect thermo-mechanical damages in the surface layer. In-process detection methods allow a fast reaction to negative changes before producing a large amount of rejects and open the possibility to save additional time for post-process inspection. However, these are not industrially used yet, since boundary conditions and application limits are not defined so far. This study shows the potential of a grinding process control based on a soft sensor combining a thermal limit in a $${P}_{c}^{{\prime}{\prime}}$$

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in dependence of the contact time Δt allows to identify/avoid grinding burn starting from light tempering zones. Furthermore, the BN is well suited for the detection of detrimental residual stress changes (tensile) occurring even before tempering zones are generated. The developed process control based on this combination optimizes the process parameters to prevent negative thermo-mechanical surface changes while keeping the productivity of the process as high as possible. The applicability is demonstrated for external cylindrical and non-circular grinding processes. Due to the radius varying over the workpiece circumference, the latter ones require special demands on signal evaluation, resolution and control speed.
Suppression of the long non-coding RNA LINC01279 triggers autophagy and apoptosis in lung cancer by regulating FAK and SIN3A
Authors: Wu Jiancong , Huang Xiaobi , Li Xiaofang , Zhou Honglian , Chen Xiaorao , Chen Yongyang , Guo Yudong , Huang Jian , Huang Hanqing , Huang Zhong , Chen Guoan , Yang Zhixiong , Zhang Jian , Su Wenmei 
Published: January 2024

AbstractLong non-coding RNAs play critical roles in the development of lung cancer by functioning as tumor suppressors or oncogenes. Changes in the expression of LINC01279 have been associated with cell differentiation and human diseases. However, the mechanism underlying LINC01279 activity in tumorigenesis is not clear. Here, we analyzed the function of LINC01279 in lung adenocarcinoma using clinical samples, xenografts, and non-small-cell lung cancer cell lines. We found that LINC01279 is highly expressed in lung adenocarcinoma and may be considered as a predictive factor for this cancer. Knockdown of LINC01279 prevents tumor growth in xenografts and in cancer cell lines by activating autophagy and apoptosis. Molecularly, we revealed that LINC01279 regulates the expression of focal adhesion kinase and extracellular-regulated kinase signaling. In addition, it complexes with and stabilizes the transcriptional co-repressor SIN3A protein. Suppression of focal adhesion kinase and SIN3A also induces apoptosis and prevents tumor progression, suggesting that they may at least in part mediate the oncogenic activity of LINC01279. These results identify LINC01279 as a possible oncogene that plays an important role in the development of lung cancer. Our findings provide insights into the mechanism underlying LINC01279-mediated oncogenesis of lung adenocarcinoma. They may help to discover potential therapeutic targets for cancer diagnosis and prognosis.
Biomarker in Hepatocellular Carcinoma
Authors: Basthi Mohan Pooja , Lochan Rajiv , Shetty Shiran 
Published: January 2024

AbstractLiver cancer is one of the most prevalent types of cancer and a major contributor to the socioeconomic burden worldwide. The pathogenesis of hepatocellular carcinoma (HCC) is contributed by various etiological factors like virus infection, excessive alcohol consumption, exposure to toxins, or metabolic disorders. Majority of patients are diagnosed with late-stage HCC, which restricts its management to only palliative care. HCC, if diagnosed early, increases the survival and quality of life. Currently available biomarker (alpha-fetoproteins) have several limitations, that impede the early diagnosis and staging of cancer. This warrants the continous search in pursuit of a novel biomarker. Several research works in diverse areas have contributed to the identification of various novel biomarkers that have shown multifaceted application in early disease diagnosis, which further aid in targeted and effective therapy that can prevent cancer progression. This improves the overall health status of the patient along with significant reduction in caretaker’s burden. With the aid of novel technologies, several biomarkers have been investigated and validated in mutliple preliminary research works. Therefore in this review, we have outlined various novel biomarkers that showed promising outcomes in their trials and we have highlighted the developing areas that act as game changers in cancer diagnosis and management.
Disclosing the potential of Cupressus leylandii A.B. Jacks & Dallim, Eucalyptus globulus Labill., Aloysia citrodora Paláu, and Melissa officinalis L. hydrosols as eco-friendly antimicrobial agents
Authors: Almeida Heloísa H. S. , Crugeira Pedro J. L. , Amaral Joana S. , Rodrigues Alírio E. , Barreiro Maria-Filomena 
Published: January 2024

AbstractAntimicrobial resistance is a major global health concern, threatening the effective prevention and treatment of infections caused by microorganisms. These factors boosted the study of safe and green alternatives, with hydrosols, the by-products of essential oils extraction, emerging as promising natural antimicrobial agents. In this context, four hydrosols obtained from Cupressus leylandii A.B. Jacks & Dallim, Eucalyptus globulus Labill., Aloysia citrodora Paláu and Melissa officinalis L. were studied. Their chemical composition comprises neral, geranial, 1,8-cineole, terpinen-4-ol, and oplopanonyl acetate, compounds with recognised antimicrobial activity. Concerning antimicrobial activity, significant differences were found using different hydrosol concentrations (10–20% v/v) in comparison to a control (without hydrosol), showing the potential of the tested hydrosols to inhibit the microbial growth of Escherichia coli, Staphylococcus aureus, and Candida albicans. A. citrodora hydrosol was the most effective one, inhibiting 90% of E. coli growth and 80% of C. albicans growth, for both hydrosol concentrations (p < 0.0001). With hydrosol concentration increase, it was possible to observe an improved antimicrobial activity with significant reductions (p < 0.0001). The findings of this work indicate the viability of reusing and valuing the hydrosols, encouraging the development of green applications for different fields (e.g., food, agriculture, pharmaceuticals, and cosmetics).
Graphical Abstract
Development of Drug Products for the Treatment of Acute Radiation Syndrome
Authors: Libero Marzella 
Published: January 2024

Abstract
The Food and Drug Administration’s (FDA) approval to market drug products for use as medical countermeasures, to prevent or mitigate injury caused by various threat agents, is commonly based on evidence of efficacy obtained in animals. Animal studies are necessary when human studies are not feasible and challenge studies are not ethical. The successful development of countermeasures to radio-nuclear threats that cause Acute Radiation Syndrome (ARS) provides the opportunity to explore potential areas of overlap in the scientific approaches to studies of injuries caused by radiation and sulfur mustard exposures in animals. The aim is to evaluate the available scientific knowledge for radiation threat agents and sulfur mustard for potential analogies of fundamental mechanisms of organ injury and dysfunction. This evaluation is needed to determine the applicability of regulatory strategies for product development and approval adopted by manufacturers of countermeasures for radiation threat agents. Key elements of an efficient development plan based on animal efficacy studies include characterizing the pathophysiology of organ injury and the mechanism of action (MOA) of the countermeasure; modeling the clinical condition in animals to establish the manifestations of the injury caused by various levels of exposures to the threat agent and the response to various doses of the countermeasure candidate; as well as selecting a maximally effective human dose.
David against Goliath: from riders’ protest to platform cooperativism
Authors: Guichoux Arthur 
Published: January 2024

AbstractFaced with platforms such as Uber, riders are resisting individually and organising actions such as Riders X Derechos in Spain. Some of these ‘new proletarians’ have even organised themselves into cooperatives. To the global utopia of investor-owned platforms, platform cooperativism opposes the utopia of delivery without exploitation or carbon emissions through local cooperatives owned by riders. Based on the case study of the Mensakas cooperative in Barcelona, this ethnography analyses the link between riders’ protests and cooperative platforms. It questions the concrete effects of ‘counter-platform politics’ and the relationship between politics and labour. It also examines the strategies of intercooperation in the ‘cyclelogistical’ sector to understand the institutional, social, and political conditions that foster the ‘re-embeddedness’ of the bike delivery market.
Platforms in the city and cities at the service of platforms: An urban perspective on the platform economy and workers’ responses
Authors: Dif-Pradalier Maël , Jammet Thomas , Tiberghien Julie , Bignami Filippo , Cuppini Niccolo 
Published: January 2024

AbstractThe social and economic impacts of the emerging platform economy are most obvious in urban settings, where platforms are giving rise to unfamiliar dynamics of inclusion and exclusion, cooperation and division, as well as social and political integration and fragmentation. Platform urbanisation has created a new and unprecedented kind of politics. It has given rise to new political spaces and new subjectivities, resulting in a permanent reorganisation of ‘historical’ assemblages of territory, authority and rights. Drawing on the results of the European-based PLUS Project (Platform Labour in Urban Spaces: Fairness, Welfare, Development), this themed collection offers a fresh perspective on the platform economy by analysing it in terms of the relationship between urban contexts and the ongoing platformisation process, with an emphasis on how this relationship is reshaping (platform) labour and reconfiguring (or even reinvigorating) social action. Along the way, the articles in this issue consider whether platforms are useful for the development of urban environments and labour markets, or whether urban environments and labour markets are useful for the development of platforms. Likewise, they seek to identify the conditions under which relevant actors can mobilise and build alliances to ensure that such forms of development can be made to benefit not only workers but also (urban) citizens and the (urban) environment in general.
Naming and Describing Disability in Law and Medicine
Authors: Robinson Heloise , Herring Jonathan 
Published: January 2024

AbstractThis article explores the effects of naming and describing disability in law and medicine. Instead of focusing on substantive issues like medical treatment or legal rights, it will address questions which arise in relation to the use of language itself. When a label which is attached to a disability is associated with a negative meaning, this can have a profound effect on the individual concerned and can create stigma. Overly negative descriptions of disabilities can be misleading, not only for the individual, but also more broadly in society, if there are inaccurate perceptions about disability in the social context. This article will examine some relevant examples of terminology, where these issues arise. It will also suggest that the role of medicine and the law in naming and describing disability is particularly important because in these areas there is, perhaps more than anywhere else, a recognized source of authority for the choice of terminology. Labels and descriptions used in the medical and legal contexts can not only perpetuate existing stigmatization of disabled people, but can also contribute to creating stigma at its source, given that the words used in these contexts can constitute an exercise of power.
Conspicuous leisure, time allocation, and obesity Kuznets curves
Authors: Mathieu-Bolh Nathalie , Wendner Ronald 
Published: January 2024

AbstractOur growth model explores the complex relationship between income, obesity, and changes in exercise-related behavior. Combining Becker’s theory of time allocation (The Economic Journal 75(299), 493–517, 1965) with Veblen’s theory of conspicuous leisure (The Theory of the Leisure Class, 1st ed. New York: Macmillan, 1899), we determine conditions for dynamic and static obesity Kuznets curves. Considering food consumption and exercise choices, we show that dynamic and static Kuznets curves result from the rising opportunity cost of exercise and peer influence, both increasing with income. Focusing on calorie expenditure, we investigate the rise and slowdown in obesity prevalence in the USA and the correlation between obesity and income per worker. Our numerical simulations indicate that, as the economy grows, exercise choices slow down the rise in obesity prevalence but do not generate a dynamic Kuznets curve in the USA. By contrast, they generate a static Kuznets curve for a population cross section. We discuss policy implications of our findings.
Optimal unemployment insurance with behavioral agents
Authors: Yeung Hon Chung 
Published: January 2024

AbstractThis paper studies how behavioral biases affect the optimal unemployment insurance. I revisit the optimal UI of Landais et al. (2018) and show how the optimal UI formula is modified and leads to novel economic insights. The optimal UI replacement rate is the conventional Baily-Chetty replacement rate, which solves the trade-off between liquidity and job-search incentives, plus a market tightness correction term which shows how welfare is affected by UI through tightness, and plus a behavioral bias correction term, which shows how welfare is affected by UI through job search effort.
Comprehensive evaluation of body composition in a wide age range of Iranian adults using bioelectrical impedance analysis: Tehran Lipid and Glucose Study
Authors: Mohamadzadeh Mahdieh , Valizadeh Majid , Hosseinpanah Farhad , Momenan Amirabbas , Mahdavi Maryam , Barzin Maryam , Azizi Feridoun 
Published: January 2024

Abstract

Objective:
To evaluate sex- and age-stratified body composition (BC) parameters in subjects with wide age range of 20–79 years.

Design:
Cross-sectional.

Setting:
Participants of Tehran Lipid and Glucose Study (TLGS).

Participants:
Two thousand nine hundred seventy participants met our inclusion criteria. They were divided into five age groups, and BC parameters were analysed based on sex and age using a bioelectrical impedance analyser (BIA).

Result:
The mean age of the participants was 42·1 ± 12·5 years, and 54 % of them were males. The mean BMI was 26·7 ± 3·7 kg/m2. Obesity indices were significantly higher in females (P < 0·001); however, skeletal muscle mass (SMM) and fat-free mass (FFM) were significantly higher in males (P < 0·001). Both SMM and FFM decreased significantly after the age of 50 years. Obesity indices significantly increased from the age group of 20–29 to 30–39 years in males and the age groups of 30–39 to 40–49 years and 40–49 to 50–59 years in females. The fat mass ratio (fat mass/SMM) showed two peaks in both sexes (after the ages of 30 and 50 years in males and 40 and 50 years in females). A strong correlation was found between BMI and percentage of body fat (r = 0·823 in females v. r = 0·768 in males).

Conclusion:
This is the first community-based study in the MENA region identifying sex- and age-stratified BC values using BIA. Our findings can be used as a reference for comparison in appropriate settings.
Backwards Causation and Max Black's Abominable Conjunction
Authors: Garrett Brian 
Published: January 2024

AbstractPhilosophers dispute whether an effect can be earlier than its cause (i.e. whether backwards causation can occur). For example, could a trainwreck cause a psychic to have earlier knowledge of it? Max Black tried to show backwards causation to be impossible but he failed to do so, or so I will argue. Nonetheless, his famous article can still teach us something important about certain cases of backwards causation.
Galileo Observation of Electron Spectra Dawn‐Dusk Asymmetry in the Middle Jovian Magnetosphere: Evidence for Convection Electric Field
Authors: Yuan Chongjing , Roussos Elias , Wei Yong , Krupp Norbert , Liu Zhiyang , Wang Jianzhao 
Published: January 2024

AbstractIn Jupiter's middle magnetosphere, debate remains on the controlling physics of electron acceleration to the ultrarelativistic regime. Some local‐time asymmetric processes regulating MeV electrons may have their hold across electron spectra, leaving imprints down to 10–100s keV energies. Spectra at these lower energies can be measured with finite energy resolution, which is hardly achieved for MeV electrons. We investigate 10–100s keV electron spectra using Galileo measurements. We show that at 15–20 RJ, the power‐law exponents exhibit a previously unexpected dawn‐dusk asymmetry. This asymmetry is more prominent for 100s‐keV spectra, persistent but enhanced from 1996 to 2001. These match the theory of transport driven by a dawn‐to‐dusk electric field. Contrary to past expectations of dawn‐to‐dusk electric field at Io plasma torus (IPT) extending outward from 6 RJ, the origin of the field we infer may be completely different, despite its orientation and impacts on electron energization similar with the IPT one.
Stratospheric Temperature and Ozone Impacts of the Hunga Tonga‐Hunga Ha'apai Water Vapor Injection
Authors: Fleming Eric L. , Newman Paul A. , Liang Qing , Oman Luke D. 
Published: January 2024

AbstractThe January 2022 eruption of the Hunga Tonga‐Hunga Ha'apai underwater volcano injected a large amount of water vapor into the mid‐stratosphere. This study uses model simulations to investigate the resulting stratospheric impacts out to 2031. Maximum radiatively‐driven model temperature changes occur in the Southern Hemisphere (SH) subtropics in April–May 2022, with warming of ∼1 K in the lower stratosphere and cooling of 3 K in the mid‐stratosphere. The radiative cooling combined with adiabatic cooling driven by the quasi‐biennial oscillation meridional circulation explains the near‐record cold anomaly observed in the SH subtropical mid‐stratosphere. Projected ozone responses maximize in 2023–2024 as the water vapor plume is transported globally throughout the stratosphere and mesosphere. The excess H2O increases the OH radical, causing a negative global ozone response (2%–10%) in the upper stratosphere and mesosphere due to increased odd hydrogen‐ozone loss, and a small positive ozone response (0.5%–1%) in the mid‐stratosphere due to interference of the NOx catalytic loss cycle by the additional OH. In the lower stratosphere, the excess H2O is projected to increase polar stratospheric clouds and springtime halogen‐ozone loss, enhancing the Antarctic ozone hole by 25–30 DU in 2023. Arctic impact is small, with maximum additional ozone loss of 4–5 DU projected in spring 2024. These responses diminish after 2024 to be quite small by 2031, as the excess H2O is removed from the stratosphere with a 2.5‐year e‐folding time. Given the year‐to‐year variability of the stratosphere, the magnitudes of these ozone responses may be below the threshold of detectability in observations.
MAVEN/IUVS Observations of OH Prompt Emission: Daytime Water Vapor in the Thermosphere of Mars
Authors: Stevens M. H. , Cangi E. M. , Deighan J. , Jain S. K. , Chaffin M. S. , Evans J. S. , Gupta S. , Clarke J. T. , Schneider N. M. , Curry S. M. 
Published: January 2024

AbstractWe report the highest altitude detection of water vapor on Mars to date. The daytime limb observations by the Imaging Ultraviolet Spectrograph (IUVS) on the Mars Atmosphere and Volatile EvolutioN (MAVEN) spacecraft are of hydroxyl (OH) prompt emission near 308 nm, which is excited directly from the photodissociation of water vapor by the solar Lyman‐α flux. Average IUVS daytime water vapor densities near 130 km are 3 × 107 cm−3 around perihelion. The water vapor densities diurnally vary with a peak near midday and no detection at sunrise and sunset. To evaluate the large daytime water vapor densities for self‐consistency, we also report the simultaneous observation of OH solar fluorescence emission near 308 nm in the thermosphere, which enables the retrieval of OH densities. Using a one‐dimensional photochemical model initialized with the daytime IUVS water vapor densities, modeled peak OH densities are in good agreement with the observed IUVS peak OH densities. Because the observed thermospheric temperatures are controlled by solar insolation and cross the water frost point during the day, we suggest that the IUVS observed water vapor is created by the daily sublimation of water ice particles supplied from below. We discuss the implications of the IUVS observations on the present day loss of water vapor from Mars in the form of atomic hydrogen.