bluuebunny/crossref_metadata_2025_split huggingface dataset:
Are traditional interviews more prone to effects of impression management than structured interviews?
Authors: Bill Benedikt , Melchers Klaus G. , Steuer Jana , Eisele Edith 
Published: November 2023

AbstractResearch on whether interviewees can improve their interview ratings through impression management (IM) relative to an honest condition has focused on highly structured interviews whereas traditional interviews have received little attention. Thus, this study aimed to determine how prone traditional compared to highly structured interviews are to effects of IM. Therefore, we conducted simulated selection interviews using a 2 × 2 within‐subjects design. All participants went through a condition in which they were asked to present themselves as honestly as possible and a condition in which they were instructed to act like an applicant. Additionally, each interview contained eight traditional and eight structured questions. The differences in the usage of self‐reported honest and deceptive IM between the honest and applicant conditions were comparable for both interview types. Furthermore, interview ratings were better in the applicant condition compared to the honest condition, and importantly, this improvement was larger for the traditional interview part compared to the structured interview part. Even though the larger performance improvement was not reflected in self‐reported honest and deceptive IM, our results suggest that it is easier for applicants to intentionally improve their performance ratings in traditional interviews. Additionally, performance improvements correlated positively with applicants' ability to identify criteria.
PADRES: a phase 2 clinical trial of neoadjuvant axitinib for complex partial nephrectomy
Authors: Hakimi Kevin , Campbell Steven C. , Nguyen Mimi V. , Rathi Nityam , Wang Luke , Meagher Margaret F. , Rini Brian I. , Ornstein Moshe , McKay Rana R. , Derweesh Ithaar H. 
Published: November 2023

ObjectiveTo report the results of PADRES (Prior Axitinib as a Determinant of Outcome of Renal Surgery, NCT03438708), a study investigating neoadjuvant axitinib for tumours of high complexity with imperative indication for partial nephrectomy (PN).MethodsWe conducted a single‐arm phase II clinical trial of localized (cT1b‐cT3M0) clear‐cell renal cell carcinoma (RCC) patients with imperative indications for nephron preservation, where PN is a high‐risk procedure due to complexity (RENAL score 10–12). Axitinib 5 mg was administered twice daily for 8 weeks with repeat imaging at completion, followed by surgery. The primary outcome was successful completion of planned PN following axitinib treatment. Secondary objectives included changes in tumour diameter, RENAL nephrometry score, renal function and Response Evaluation Criteria in Solid Tumours (RECIST) v1.1, and surgical complications.ResultsTwenty‐seven patients were enrolled (median age 69 years). Prior to therapy, twenty patients (74.0%) had ≥ clinical T3a staged tumours. Axitinib resulted in reductions in tumour diameter (7.5 vs 6.2 cm; P < 0.001) and RENAL score (11 vs 10; P < 0.001). Nine patients (33.3%) had partial response based on RECIST and nine (33.3%) were clinically downstaged. PN was performed in twenty patients (74.0%); twenty‐five patients (96.2%) had negative margins. Six patients (22.2%) had Clavien III–IV complications. The median change in estimated glomerular filtration rate (preoperative to last follow‐up) was 8.5 mL/min/1.73 m2.ConclusionNeoadjuvant axitnib resulted in reductions in tumour size and complexity, enabling safe and feasible PN and functional preservation in patients with complex renal masses and imperative indication.
Recent dental visits and family caregiving among individuals with dental symptoms: A nationwide cross‐sectional study in Japan
Authors: Ishimaru Miho , Zaitsu Takashi , Kino Shiho , Inoue Yuko , Taira Kento , Takahashi Hideto , Tamiya Nanako 
Published: November 2023

AbstractObjectivesWith the increasing number of family caregivers due to the ageing population, physical and mental health problems among caregivers are of concern. However, few studies have evaluated their oral health. This study aimed to evaluate the association between being a family caregiver and recent dental visits for dental symptoms in Japan, with consideration of gender.MethodsA cross‐sectional study was conducted using the 2016 Comprehensive Survey of Living Conditions (CSLC) in Japan. Participants with dental symptoms were included in this study. The primary outcome was recent dental visits. The exposure variable of interest was being a primary caregiver for a family member requiring long‐term care. A logistic regression analysis was conducted adjusting for contributing factors such as age, gender, marital status, working hours per week, education, household expenditure per month, self‐rated health and the interaction between gender and caregiving. A stratified analysis by gender was also performed.ResultsOf the 5100 eligible participants, 233 (4.6%) were family caregivers. Of all participants, 2746 (53.8%) reported dental visits. The adjusted odds ratio (aOR) of family caregivers having recent dental visits was 0.83 (95% confidence interval [CI], 0.64–1.09). In a gender stratified analysis, family caregivers were less likely to visit dental clinics than were non‐family caregivers in the male subsample (aOR: 0.56, 95% CI: 0.34–0.92) but not in the female subsample (aOR: 0.99, 95% CI: 0.72–1.38).ConclusionsThe findings indicate that family caregivers, especially male caregivers, had fewer dental visits than non‐family caregivers. These findings suggest the need to improve the accessibility of dental clinics to family caregivers with dental symptoms.
Giant papillary hemangioma—A rare tumor with an exceptional size
Authors: Abdo Maryam , Dykstra Jordan A. , Meyer Anders , Dai Hongyan 
Published: November 2023

AbstractPapillary hemangioma (PH) is a recently described vascular tumor with a predilection for the skin of the head and neck. Histopathologically, it is characterized by a bland endothelial proliferation arranged in a papillary configuration, bearing resemblance to glomeruloid hemangioma seen in the context of polyneuropathy, organomegaly, endocrinopathy, monoclonal protein, skin changes syndrome. The largest cutaneous PH reported to date measured 1.5 cm in greatest dimension. Here, we report a case of PH with an alarming size of 10 cm. We present this case to add to the limited literature on this rare tumor, highlight the histopathologic differences between PH and its mimics, and emphasize the variable nature of PH tumor size.
Endoscopic full‐thickness resection for gastric submucosal tumors: Japanese multicenter prospective study
Authors: Shichijo Satoki , Uedo Noriya , Sawada Atsushi , Hirasawa Kingo , Takeuchi Hirohisa , Abe Nobutsugu , Miyaoka Masaki , Yao Kenshi , Dobashi Akira , Sumiyama Kazuki , Ishida Tsukasa , Morita Yoshinori , Ono Hiroyuki 
Published: November 2023

ObjectivesEarly gastric cancer endoscopic resection (ER) is prominent in Japan. However, evidence regarding ER of gastric submucosal tumors (SMT) is limited. This prospective multicenter phase II study investigated the efficacy and safety of endoscopic full‐thickness resection (EFTR) for gastric SMT.MethodsEndoscopic full‐thickness resection indication for gastric SMT was 11–30 mm, histologically proven or clinically suspicious (irregular margin, increasing size, or internal heterogeneity) gastrointestinal stromal tumors (GIST), with no ulceration and intraluminal growth type. The primary end‐point was the complete ER (ER0) rate, with a sample size of 42.ResultsWe enrolled 46 patients with 46 lesions between September 2020 and May 2023 at seven Japanese institutions. The mean ± SD (range) endoscopic tumor size was 18.8 ± 4.5 (11–28) mm. The tumor resection and defect closure times were 54 ± 26 (22–125) min and 33 ± 28 (12–186) min, respectively. A 100% ER0 was achieved in all 46 patients. The EFTR procedure was accomplished in all patients without surgical intervention. One patient had delayed perforation and was managed endoscopically. GIST accounted for 76% (n = 35) of the cases. R0, R1, and RX rates were 33 (77%), 3 (6.5%), and 7 (15%), respectively.ConclusionEndoscopic full‐thickness resection for gastric SMT of 11–30 mm is efficacious. It warrants further validation in a large‐scale cohort study to determine the long‐term outcome of this treatment for patients with gastric GIST.
Can the delivery of behavioural support be improved in the NHS England Low‐Calorie Diet Programme? An observational study of behaviour change techniques
Authors: Evans Tamla S. , Drew Kevin J. , McKenna Jim , Dhir Pooja , Marwood Jordan , Freeman Charlotte , Hill Andrew J. , Newson Lisa , Homer Catherine , Matu Jamie , Radley Duncan , Ells Louisa J. 
Published: November 2023

AbstractBackgroundPrevious research has illustrated a drift in the fidelity of behaviour change techniques (BCTs) during the design of the pilot NHS England Low‐Calorie Diet (NHS‐LCD) Programme. This study evaluated a subsequent domain of fidelity, intervention delivery. Two research questions were addressed: (1) To what extent were BCTs delivered with fidelity to providers programme plans? (2) What were the observed barriers and facilitators to delivery?MethodsA mixed‐methods sequential explanatory design was employed. Remote delivery of one‐to‐one and group‐based programmes were observed. A BCT checklist was developed using the BCT Taxonomy v1; BCTs were coded as present, partially delivered, or absent during live sessions. Relational content analysis of field notes identified observed barriers and facilitators to fidelity.ResultsObservations of 122 sessions across eight samples and two service providers were completed. Delivery of the complete NHS‐LCD was observed for five samples. Fidelity ranged from 33% to 70% across samples and was higher for group‐based delivery models (64%) compared with one‐to‐one models (46%). Barriers and facilitators included alignment with the programme's target behaviours and outcomes, session content, time availability and management, group‐based remote delivery, and deviation from the session plan.ConclusionsOverall, BCTs were delivered with low‐to‐moderate fidelity. Findings indicate a dilution in fidelity during the delivery of the NHS‐LCD and variation in the fidelity of programmes delivered across England. Staff training could provide opportunities to practice the delivery of BCTs. Programme‐level changes such as structured activities supported by participant materials and with sufficient allocated time, might improve the delivery of BCTs targeting self‐regulation.
Causal relationship between sleep apnea and non‐alcoholic fatty liver disease: A Mendelian randomization study
Authors: Zhang Ziqi , Li Meng , Ji Guang , Zhang Li 
Published: November 2023

AbstractBackgroundObservational studies indicate that sleep apnea is associated with non‐alcoholic fatty liver disease (NAFLD) and its related metabolic features, independent of confounding factors including obesity. However, the causal relationships remain to be determined.MethodsUnivariable and multivariable Mendelian randomization (MR) analyses were performed to investigate the causal relationship between sleep apnea and NAFLD, along with its typical features including liver function, glycemic traits and lipid profiles. Summary‐level data for sleep apnea were obtained from the Finngen consortium (33,423 cases and 307,648 controls). Summary‐level data for NAFLD were available from a GWAS meta‐analysis (8434 cases and 770,180 controls), and data for 12 NAFLD‐related features from corresponding published GWASs. The inverse variance weighted (IVW) analysis was employed as the primary statistical method. Bidirectional MR and CAUSE analysis were conducted to avoid reverse causality and false positive findings.ResultsIn univariable MR analyses, we found evidence to support a causal effect of genetically predicted sleep apnea on NAFLD (OR = 1.50, 95% CI = 1.18–1.91) and HDL‐C (β = −0.045, 95% CI = ‐0.090 to −0.001). In reverse MR, genetically predicted serum TG was associated with an increased risk of sleep apnea (OR = 1.07, 95% CI = 1.02–1.12), while genetically predicted HDL‐C was associated with a decreased risk of sleep apnea (OR = 0.93, 95% CI = 0.89–0.98). After adjusting body mass index or educational attainment, none of these causal associations were retained. However, CAUSE method and MR analyses focusing on lipoprotein subfractions supported a causal effect of sleep apnea on HDL‐C and HDL subfractions.ConclusionThis MR study indicated that sleep apnea has no direct causal association with NAFLD, elevated liver enzymes and insulin resistance. Our results showed suggestive inverse associations of genetically predicted sleep apnea on HDL‐C and HDL subfractions, indicating that both HDL‐C levels and HDL function may be causally implicated in sleep apnea.
International teaching practices in dental trauma education
Authors: O'Connell Anne C. , Olegário Isabel C. 
Published: November 2023

AbstractBackground/AimSeveral publications highlight the insufficient knowledge possessed by dentists and dental students regarding the management of traumatic dental injuries (TDIs). A lack of clinical experience during Undergraduate (UG) education could explain the reported deficits in managing dental trauma post‐graduation. Despite its importance in dentistry, there are very few reports on how, where and who teaches Dental Traumatology (DT) in the UG curriculum. The aim of this study was to investigate teaching practices in DT around the world in UG education.Materials and MethodsUG educators involved in DT teaching activities were invited to complete an online questionnaire hosted on Qualtrics®. The survey consisted of close‐ended and open‐ended questions on their teaching practices in DT. Only one answer per institution was included in the final descriptive analysis.ResultsA total of 203 responses from 164 institutions were obtained from 69 countries. All institutions reported that DT is included in their UG curriculum, and is mainly taught within Paediatric Dentistry and Endodontics. Most teaching and evaluation was delivered in traditional format. The number of contact hours dedicated to DT teaching activities ranged from 2 to 185 h (median = 10). Only 35% of institutions had a unified approach across disciplines. DT was taught as a separate course/module in 23% of the universities. Insufficient exposure to emergency care and the lack of formal clinical exposure to TDI was highlighted by many institutions. The need for a core curriculum was supported by 84% of the institutions with agreement on essential topics required at UG level.ConclusionsTeaching practices in DT varied internationally. Very few teaching hours were devoted to DT and many institutions identified a need for increased clinical exposure. There was a desire for a standardised coherent approach to DT in the UG education with suggestions to improve educational resources.
Treatment outcomes of permanent teeth with uncomplicated and complicated crown fractures and factors associated with pulp survival: A retrospective study
Authors: Cheng Jing , Li Jiahui , Li Chunmei , Zhang Xiaojin , Zhao Xiaoe , Song Guangtai 
Published: November 2023

AbstractBackgroundCrown fracture is the most common injury in permanent teeth. This study aimed to evaluate the treatment outcomes of permanent teeth with uncomplicated and complicated crown fractures and to investigate potential factors.Materials and MethodsThis retrospective study included patients who experienced crown fractures in permanent teeth from 2018 to 2021 with at least 12 months of follow‐up. All complicated crown fractured teeth were treated with pulpotomy, while for teeth with uncomplicated crown fractures, three treatments (restoration, indirect pulp capping, or pulpotomy) were employed. The chi‐square test was used to compare the prognosis of teeth with uncomplicated and complicated crown fractures. Potential factors associated with pulp survival including gender, interval, root development, enamel infraction, mobility, concomitant luxation injury, treatment, and coronal restoration were identified via Cox regression analysis.ResultsA total of 307 teeth from 220 children (average age = 9.3 ± 1.4 years; age range, 6–14 years) with a median follow‐up of 23 months were included, and 82.1% of all teeth had immature roots. Complicated crown fractured teeth (93.6%, 102/109) had a significantly higher success rate compared with uncomplicated crown fractured teeth (85.4%, 169/198) (p < .05). Pulpotomy (96.9%) had the highest success rate of all treatments for uncomplicated crown fractures, followed by only restoration (85.0%) and indirect pulp capping (76.9%). The success rate of teeth that received pulpotomy was significantly higher than those treated by indirect pulp capping (p < .05). In uncomplicated crown fractures, teeth with Class II mobility were more vulnerable to failure than teeth without abnormal mobility (HR = 34.83; 95% CI, 9.59–126.56; p < .05); teeth that received pulpotomy were less prone to failure than teeth that received indirect pulp capping (HR = 13.53; 95% CI, 1.58–115.72; p < .05).ConclusionCrown fractures treated with conservative pulp treatments had a relatively highly favorable prognosis. The prognosis of uncomplicated crown fractured teeth was impacted by the severity of periodontal injury and treatment strategies. Accurate diagnosis and identification of micro‐exposures are important. Dentists should take multiple risk factors into account and select optimal treatment strategies.
Topical and field‐tested residual effects of globally used insecticides on the parasitoid Tamarixia radiata released against the Asian citrus psyllid, Diaphorina citri
Authors: Rugno Gabriel Rodrigo , Qureshi Jawwad A. 
Published: November 2023

AbstractTamarixia radiata (Waterston) (Hymenoptera: Eulophidae) is the key parasitoid of the Asian citrus psyllid (ACP), Diaphorina citri Kuwayama (Hemiptera: Liviidae), in several citrus‐producing regions of the world. Chemical control is common to suppress ACP. Insecticides from globally used classes of insecticides for controlling ACP were tested on its primary parasitoid, T. radiata. Evaluations included dose–response of dimethoate, fenpropathrin, and imidacloprid in a topical application and lethal and sublethal effects from residues of imidacloprid, fenpropathrin, horticultural mineral oil (HMO), pyrethrin, and spirotetramat at 1, 3, and 7 days after application (DAA) of sprays on citrus trees in the orchard. The parasitism potential of the females that survived insecticide exposure was evaluated on untreated nymphs of ACP developing on citrus shoots and untreated parasitoid females were evaluated on nymphs treated with insecticides. In the topical application, imidacloprid was 8× more toxic to T. radiata than dimethoate and fenpropathrin. The lethal effect of the residues from imidacloprid and fenpropathrin sprays was more detrimental than other insecticides. Parasitoid mortality from 1‐ to 3‐day‐old residues averaged 90–96% for imidacloprid, 83–94% for fenpropathrin, 38–77% for pyrethrin, 43–44% for HMO, and 17–33% for spirotetramat. Parasitism by females that survived insecticide exposure was reduced by 71–88% from fenpropathrin, 28–59% from pyrethrin, 31–55% from imidacloprid, 44–4% from spirotetramat, and 39–11% from HMO compared to untreated females. The lethal and sublethal effects of all insecticides on T. radiata were significantly reduced at 7 DAA, suggesting a lower impact on its establishment and performance if releases are made after a week from spray application.
Are we there yet? A critical evaluation of sudden and unexpected death in epilepsy models
Authors: Smith Jonathon , Richerson George , Kouchi Hayet , Duprat Fabrice , Mantegazza Massimo , Bezin Laurent , Rheims Sylvain 
Published: November 2023

AbstractAlthough animal models have helped to elaborate meaningful hypotheses about the pathophysiology of sudden and unexpected death in epilepsy (SUDEP), specific prevention strategies are still lacking, potentially reflecting the limitations of these models and the intrinsic difficulties of investigating SUDEP. The interpretation of preclinical data and their translation to diagnostic and therapeutic developments in patients thus require a high level of confidence in their relevance to model the human situation. Preclinical models of SUDEP are heterogeneous and include rodent and nonrodent species. A critical aspect is whether the animals have isolated seizures exclusively induced by a specific trigger, such as models where seizures are elicited by electrical stimulation, pharmacological intervention, or DBA mouse strains, or whether they suffer from epilepsy with spontaneous seizures, with or without spontaneous SUDEP, either of nongenetic epilepsy etiology or from genetically based developmental and epileptic encephalopathies. All these models have advantages and potential disadvantages, but it is important to be aware of these limitations to interpret data appropriately in a translational perspective. The majority of models with spontaneous seizures are of a genetic basis, whereas SUDEP cases with a genetic basis represent only a small proportion of the total number. In almost all models, cardiorespiratory arrest occurs during the course of the seizure, contrary to that in patients observed at the time of death, potentially raising the issue of whether we are studying models of SUDEP or models of periseizure death. However, some of these limitations are impossible to avoid and can in part be dependent on specific features of SUDEP, which may be difficult to model. Several preclinical tools are available to address certain gaps in SUDEP pathophysiology, which can be used to further validate current preclinical models.
Generating mutual support in multifamily therapy to promote father involvement and family communication quality of Chinese families of adolescents with Attention Deficit Hyperactivity Disorder: A qualitative study
Authors: Lo Julia Wing Ka , Ma Joyce Lai Chong 
Published: November 2023

AbstractPrevious studies have suggested the negative impacts of attention deficit hyperactivity disorder (ADHD) on parent–adolescent interactions. Yet engaging parents, particularly the fathers, to participate in family‐based interventions has been challenging in Chinese contexts given the traditional concerns about keeping the family's “face” and the influence of affiliate stigma. Empirical evidence supports multifamily therapy as an effective modality for parental engagement. This study explores the role of mutual support in promoting parental engagement and family communication quality of Chinese families of adolescents with ADHD. Inclusion criteria of the study were (a) Chinese family of at least one adolescent child having an ADHD diagnosis, (b) the adolescent child was aged between 11 and 15 years, and (c) the family participated in a multifamily therapy program. Families who had not completed a multifamily therapy program were excluded. Fourteen Chinese families of adolescents with ADHD who participated in a pilot multifamily therapy program from June 2017 to September 2018 were recruited for this qualitative study. Photo‐elicited parent focus groups and photo‐elicited individual interviews with adolescents were conducted. The thematic analysis revealed that a low level of hierarchy in the therapist–client relationship contributed to the building of mutual support among the families in the therapy process. The mutual support was found to play a key role in promoting acceptance, father involvement, and open communication within families of adolescents with ADHD. Discussion was conducted on the importance of the nonexpert stance of the therapist for promoting mutual support among Chinese families in a multifamily therapy process.