bluuebunny/crossref_metadata_2025_split huggingface dataset:
Metabolomic profiling of health‐benefit compounds in fresh and preserved mustard greens
Authors: Tunsagool Paiboon , Pimpak Vipawan , Promwat Poowadol , Kwandee Pincha , Kruaweangmol Pongsakorn , Roytrakul Sittiruk , Withayagiat Ulaiwan 
Published: December 2023

SummaryIn today's consumer landscape, the health benefits of preserved foods, particularly pickled and salted mustard greens, are gaining recognition on a global scale. To compare health‐promoting compounds between fresh and preserved mustard greens, a comprehensive assessment using proximate composition analysis and untargeted metabolomics was conducted. The sub‐metabolome data revealed distinct profiles for each type of mustard greens, clearly seen in their separation through principal component analysis. The metabolite profiling identified 37 metabolites with significant differences (P‐value < 0.05, −log10 P‐value > 4). Fresh mustard greens were found to be rich in 16 identified metabolites, including sulfonic acids, purines, oxepanes, monosaccharides, fatty acids, amino acids and tripeptides, offering antioxidants, gut enhancers and immune boosters. In contrast, pickled mustard greens exhibited an abundance of 20 identified metabolites in the classes of flavonoids, amino acids and dipeptides, providing antioxidant properties. Salted mustard greens, on the other hand, primarily showcased a high level of uridine diphosphate glucose (a pyrimidine class metabolite), supporting glycoconjugate synthesis among all samples. This study highlights the prominent presence of various classes of metabolites associated with health‐benefit compounds in fresh and preserved mustard greens. These insights contribute to the evaluation of health benefits in the food industry when choosing between pickled and salted preservation methods.
“I was just a shell”: Mental health concerns for women in perimenopause and menopause
Authors: O'Reilly Kate , McDermid Fiona , McInnes Susan , Peters Kath 
Published: December 2023

AbstractEarly detection of deteriorating mental health for women who are experiencing symptoms associated with perimenopause and menopause is critical to ensure the well‐being of women. Unfortunately, many women during this phase of their lives find it difficult to access relevant and timely treatment. This concurrent mixed methods study using an online survey and qualitative interviews explored Australian women's knowledge and experiences of perimenopause and menopause and specifically reports on findings associated with women's mental health. Four hundred and eleven women completed the online survey in its entirety and 25 women participated in semi‐structured interviews between April and July 2022. Survey data were analysed using SPSS and, in this article, data are presented as descriptive statistics. Qualitative interviews were analysed using thematic analysis guided by Braun and Clarke (2013; 2019). Quantitative and qualitative data specific to women's mental health were integrated into three themes: (1) increased anxiety and depression, (2) a negative impact on emotions and (3) a negative impact on self‐worth. Findings from this study will help to inform clinical services for women as it highlights the need to improve education about perimenopause and menopause for healthcare providers and women.
Mapping the hotspots and future trends of electrical stimulation for peripheral nerve injury: A bibliometric analysis from 2002 to 2023
Authors: Yang Sheng , Zhong Sen , Jin Xuehan , Fan Guoxin , Liao Xiang , Yang Xun , He Shisheng 
Published: December 2023

AbstractPeripheral nerve injuries often result in severe personal and social burden, and even with surgical treatment, patients continue to have poor clinical outcomes. Over the past two decades, electrical stimulation has been shown to promote axonal regeneration and alleviate refractory neuropathic pain. The aim of this study was to analyse this field using a bibliometric approach. Literature was searched through Web of Science Core Collection (WOSCC) for the years 2002–2023. Literature analysis included: (1) Describing publication trends in the field. (2) Exploring collaborative network relationships. (3) Finding research advances and research hotspots in the field. (4) Summarizing research trends in the field. With the number of studies in this field still increasing, a total of 693 publications were included in the analysis. This field of research is interdisciplinary in nature. Research hotspots include peripheral nerve regeneration, the treatment of neuropathic pain, materials for nerve injury repair, and the restoration of sensory function in patients with peripheral nerve injury. Correspondingly, the development of nerve conduits and systems for peripheral nerve electrical stimulation, clinical trials of peripheral nerve electrical stimulation, and tactile recovery and movement for amputees have shown significant promise as future research trends in this field.
RETRACTED: Effects of accelerated rehabilitation surgical care on the surgical site wound infection and postoperative complications in patients of lung cancer: A meta‐analysis
Authors: Fu Li‐Na , Xiao Bin 
Published: December 2023

AbstractTo comprehensively evaluate the effect of accelerated rehabilitation surgical care on perioperative wound infections and complications in patients undergoing lung cancer surgery. A comprehensive computerised search for randomised controlled trials (RCTs) of accelerated rehabilitative surgical care applied to patients undergoing lung cancer surgery was conducted using the Web of Science, PubMed, Cochrane Library, Embase, Wanfang and China National Knowledge Infrastructure databases from inception to September 2023. The literature was screened and evaluated by two investigators, and data were extracted from the final included literature. Stata software (version 17.0) was used for data analysis. Overall, 21 RCTs involving 2187 patients were included, including 1093 cases in the accelerated rehabilitation surgical care group and 1094 cases in the conventional care group. The analyses revealed that patients with lung cancer surgery who implemented accelerated rehabilitation surgical care were significantly less likely to develop postoperative wound infections (odds ratio [OR] = 0.29, 95% confidence interval [CI]: 0.17–0.49, p < 0.001) and postoperative complications (OR = 0.26, 95% CI: 0.20–0.34, p < 0.001) and shortened the hospital length of stay (standardised mean differences [SMD] = −1.93, 95% CI: −2.32 to −1.53, and p < 0.001) compared with conventional care. The effect of accelerated rehabilitation surgical care intervention in the perioperative period of lung cancer surgery patients is remarkable, as it can effectively reduce the incidence of wound infection and complications, shorten hospitalisation time and promote patient recovery.
Inequality in Planning Capacity
Authors: Morton Jennifer M. 
Published: December 2023

ABSTRACTPlanning allows us to coordinate our actions over time, and the ability to plan is crucial in many areas of our lives. I argue that while planning is deeply embedded in contemporary societies, not all individuals have equal access to the structures that support such planning. This article explores how external planning‐support structures are essential to our capacity to plan and how inequality in access to these structures can impact an individual's ability to deliberate and pursue long‐term plans. I conclude by suggesting that we need to think more deeply about unequal access to the structures that support planning directly, not just inequality in resources.
The ability of employee disclosures to reveal private information
Authors: Fan Yun , Fu Jiajia , Ji Yuan , Thomas Wayne B. 
Published: December 2023

AbstractManagers may provide incomplete disclosure for various reasons (e.g., high processing costs, operating uncertainty, proprietary concerns, agency conflicts, etc.). In contrast, rank‐and‐file employees face fewer of these limitations. Through “wisdom of the crowd” displayed on social media, employees can aggregate their individual private beliefs to provide an informative business outlook. Using employee data from Glassdoor.com, we find that employee business outlook disclosures reveal more information in loan spreads of private lending contracts when firms have more opaque information environments. Furthermore, we observe that employee disclosures help to reveal more private information when the business outlook is worsening and as employees’ collective knowledge increases. This relation is more prominent when employees are expecting worsening performance, consistent with employee disclosures revealing more private bad news. Our study demonstrates the conditions under which employee disclosures on social media are more likely to disseminate private information.
Multiple radiologist review of adrenal CT still frequently misses lateralized surgical primary aldosteronism
Authors: Mah Darren , Kneteman Mark , Przybojewski Stefan J. , Kotha Vamshi , Kline Gregory A. , Leung Alexander A. , So C. Benny 
Published: December 2023

AbstractPatients with primary aldosteronism (PA) have increased morbidity and mortality compared to those with essential hypertension. Accurate detection of lateralized PA is important so that affected patients can receive potentially curative adrenalectomy. However, around 40% of patients with lateralized PA have “normal” adrenal glands on computed tomography (CT). Additional independent review of imaging has been shown to improve diagnostic accuracy in many areas of imaging. Therefore, the authors sought to establish if multi‐reader re‐assessment of previously reported normal CT scans would result in increased detection of surgically remediable disease. The authors found that re‐assessment of CT imaging by one, two, or three additional radiologists (or a combination thereof) slightly increased the detection of lateralized disease, but these differences were not statistically significant (p > .05). Readers had low inter‐observer agreement (kappa = 0.17). If detection of a discrete nodule on CT was made a prerequisite for adrenal vein sampling (AVS), a second read by another reviewer would still result in an excess of missed cases (84.2%, 36.8%, and 65.8%, respectively, for each of the three independent reviewers). Therefore, a “normal” CT does not preclude the possibility of lateralized PA. Adrenal vein sampling should still be strongly considered wherever available and whenever surgery is considered for treatment of PA, irrespective of CT findings.
Are periodontitis and dental caries associated? A systematic review with meta‐analyses
Authors: Romandini Pierluigi , Marruganti Crystal , Romandini William Giuseppe , Sanz Mariano , Grandini Simone , Romandini Mario 
Published: December 2023

AbstractAimThe epidemiological relationship between periodontitis and caries remains controversial, and evidence synthesis is currently lacking. Therefore, this systematic review was designed to answer the following PECO question: ‘In human adults (P), do subjects suffering from periodontitis (E) have higher presence/number of untreated carious lesions and caries experience (O) than subjects not suffering from periodontitis (C)?’.Materials and MethodsObservational studies that met specific inclusion criteria established to answer to the PECO question were included. Two review authors independently searched for eligible studies, screened the titles and abstracts, carried out the full text analysis, extracted the data and performed the risk of bias assessment. In case of disagreement, a third review author took the final decision during ad hoc consensus meetings. Data synthesis was carried out through random‐effects meta‐analyses.ResultsA total of 18 studies on 21 cohorts, involving 135,018 participants, were included. Meta‐analyses showed a significant association between periodontitis and the presence of at least one tooth with either untreated carious lesions (odds ratio [OR] = 1.63; 95% confidence interval [CI]: 1.32–2.01; p <.00; I2 = 83.0%) or caries experience (decayed and filled teeth ≥ 1) (OR = 1.27; 95% CI: 1.01–1.59; p = .038; I2 = 90.0%). Moreover, subjects with periodontitis exhibited a higher number of surfaces (difference in means [MD] = 0.86; 95% CI: 0.46–1.27; p <.001; I2 = 0.0%) and teeth (MD = 0.35; 95% CI: 0.28–0.42; p <.001; I2 = 69.6%) with untreated carious lesions, as well as a higher number of teeth with caries experience (standardized difference in means  [SMD] = 1.46; 95% CI: 0.15–2.78; p = .029; I2 = 98.9%) compared with those without periodontitis. Sensitivity analyses focusing on severe periodontitis as exposure mostly showed consistent results. Estimates for caries experience were only slightly attenuated in adjusted models compared with crude models. Subgroup analyses by caries location also indicated that periodontitis was associated only with root caries, while it was not with caries affecting the anatomical crown.ConclusionsPeriodontitis was found to be associated with the presence and number of treated/untreated root carious lesions. Therefore, caries‐specific preventive measures (e.g., fluorides) should be considered for individuals with periodontitis.
A multi‐centre randomized controlled trial on alveolar ridge preservation with immediate or delayed implant placement: Need for soft‐tissue augmentation
Authors: Cosyn Jan , Seyssens Lorenz , De Bruyckere Thomas , De Buyser Stefanie , Djurkin Andrej , Eghbali Aryan , Lasserre Jérôme Frédéric , Tudts Marco , Younes Faris , Toma Selena 
Published: December 2023

AbstractAimTo assess the impact of the timing of implant placement following alveolar ridge preservation (ARP) on the need for soft‐tissue augmentation (STA) and to identify the risk factors for horizontal and vertical soft‐tissue loss.Materials and MethodsPatients with a single failing tooth in the anterior maxilla (15–25) were treated at six centres. Following tooth extraction, they were randomly allocated to the test group (immediate implant placement, IIP) or control group (delayed implant placement, DIP). ARP was performed in both groups and implants were immediately restored with an implant‐supported provisional crown. Six months after tooth extraction and ARP, a panel of five blinded clinicians assessed the need for STA on the basis of anonymized clinical pictures and a digital surface model. Lack of buccal soft‐tissue convexity and/or mid‐facial recession qualified for STA. Pre‐operative and 6‐month digital surface models were superimposed to assess horizontal and vertical soft‐tissue changes.ResultsThirty patients were included per group (test: 20 females, 10 males, mean age 53.1; control: 15 females, 15 males, mean age 59.8). The panel deemed STA as necessary in 24.1% and 35.7% of the cases following IIP and DIP, respectively. The difference was not statistically significant (odds ratio [OR] = 1.77; 95% confidence interval [CI] [0.54–5.84]; p = .343). Loss of buccal soft‐tissue profile was higher following DIP (estimated mean ratio = 1.66; 95% CI [1.10–2.52]; p = .018), as was mid‐facial recession (mean difference [MD] = 0.47 mm; 95% CI [0.12–0.83]; p = .011). Besides DIP, regression analysis identified soft‐tissue thickness (−0.57; 95% CI [−1.14 to −0.01]; p = .045) and buccal bone dehiscence (0.17; 95% CI [0.01–0.34]; p = .045) as additional risk factors for mid‐facial recession. Surgeons found IIP significantly more difficult than DIP (visual analogue scale MD = −34.57; 95% CI [−48.79 to −20.36]; p < .001).ConclusionsThis multi‐centre randomized controlled trial failed to demonstrate a significant difference in the need for STA between IIP and DIP when judged by a panel of blinded clinicians. Based on objective soft‐tissue changes, patients with thin buccal soft tissues, with a buccal bone dehiscence and treated with a delayed approach appeared particularly prone to soft‐tissue loss.
Trends in adolescent emotional problems in Wales between 2013 and 2019: the contribution of peer relationships
Authors: Anthony Rebecca , Moore Graham , Page Nicholas , Ollerhead Catherine , Parker Jack , Murphy Simon , Rice Frances , Armitage Jessica M. , Collishaw Stephan 
Published: December 2023

BackgroundEpidemiological evidence shows a substantial increase in adolescent emotional problems in many countries, but reasons for this increase remain poorly understood. We tested change in emotional problems in a national sample of young people in Wales in 2013, 2017 and 2019 using identical symptom screens, and examined whether trends were accounted for by changes in youth friendship quality and bullying.MethodsThe present study of 230,735 11–16‐year olds draws on repeat cross‐sectional data obtained on three occasions (2013, 2017 and 2019) in national school‐based surveys in Wales (conducted by the School Health Research Network). Emotional problems were assessed with a brief validated symptom screen (the SCL‐4).ResultsThere was a significant increase in emotional problem scores between 2013 and 2019 (b[95% CI] = 1.573 [1.380, 1.765]). This increase was observed for all ages and was more pronounced for girls than boys (interaction b [95% CI] = 0.229 [0.004, 0.462]) and for young people from less affluent families (interaction b [95% CI] = −0.564[−0.809, −0.319]). Of the total sample, 14.2% and 5.7% reported frequent face‐to‐face and cyberbullying respectively. There were modest decreases in friendship quality and increases in rates of bullying between 2013 and 2019, but accounting for these changes did not attenuate estimates of the population‐level increase in emotional problems.ConclusionsThis study provides evidence of a substantial increase in emotional problems among young people in Wales, particularly for young people from less affluent backgrounds. Changes in bullying or friendship quality did not explain this increase.
Augusto Bonome and his revolutionary studies on leprosy in the early 20th century
Authors: Valle F. , Magno G. , Zanatta A. 
Published: December 2023

AbstractBackgroundAugusto Bonome (1857–1922), professor at the University of Padua until 1922, was involved in a study about a particular kind of pulmonary leprosy, being the first to testify the lepromatous alterations also in the deepest parts of the respiratory tract, even though the same Gerhard Hansen (1841–1912) had denied the possibility that lungs could host Mycobacterium leprae.ObjectivesIt is necessary to reevaluate the research done by Bonome to also demonstrate how it can still be relevant today in further comprehension of leprosy.MethodsBonome's advances in leprosy studies are testified by some specimens from the Morgagni Museum of Pathological Anatomy of the University of Padua. Among the specimens, there is a peculiar case of advanced tuberous leprosy in an adolescent, who died in 1908, of which the face, the larynx, the hands and genitals are still preserved today in the Museum.ResultsThrough autoptic and histological analysis of this specimen, Bonome succeeded in identifying a peculiar case of bone toxoid‐infectious dystrophy besides characteristic leprous laryngitis, which caused the death of the young leprosy patient.ConclusionsThe results confirmed the innovative research carried on by Bonome during his medical career, being among the first to offer an important contribution to improving and revolutionary knowledge on leprosy which could still be useful today.
Advances in loquat post‐harvest preservation and the application of nanotechnology for its active packaging
Authors: Su Jingyi , Luo Yali , Cao Zhaoxin , Wang Xinyu , Ge Xueme 
Published: December 2023

AbstractThe loquat fruit is liked by many people for its rich nutritional value. However, loquats do not tolerate storage during post‐harvest storage and transportation and are prone to spoilage, making their value significantly reduced. The physical, chemical, and biological preservation techniques for loquat are discussed in this work; nevertheless, the conventional preservation techniques have drawbacks, including high costs and a lot of residues. The article reviewed major uses of nanotechnology based on its properties, which are expected to make up for the shortcomings of conventional preservation methods through extending the post‐harvest storage period and improving the post‐harvest quality of fruits and vegetables with the removal of ethylene, antioxidants, and antimicrobials. The article concludes with a summary of the ways that nanotechnology is now helping to improve the quality of loquats after harvest and increase their shelf life. The development of nanotechnology‐related preservation technologies may be very beneficial for post‐harvest fruits and vegetables because of recent advancements in quality control methods and technologies. Nanotechnology is anticipated to become a state‐of‐the‐art substitute for post‐harvest fruit and vegetable storage and transportation.
Investigation of extraction phenomena in continuous circulation coffee brewing and comparison with other brewing methods
Authors: Zwicker Matthew , Lim Loong‐Tak 
Published: December 2023

AbstractThis study investigated a continuous circulation cold brewing (CCCB) process using a modified single‐serve brewer that allowed recirculation of the brew within the single‐use capsules. The changes of total dissolved solids (TDS), titratable acidity (TA), caffeine and 5‐caffeoylquinic (5‐CQA) concentrations over time during the CCCB process were evaluated using two masses of coffee grounds (10 and 12.5 g). To elucidate the extraction process, Weibull distribution, pseudo‐first order, and pseudo‐second order models were fitted to the extraction kinetics data. The physicochemical quality of the brews produced from the CCCB process were also compared to brews produced though traditional cold brew steeping (separated by gravity and forced filtration) and single‐serve hot brewing processes. Significantly lower (p < 0.05) TDS, TA, and 5‐CQA concentrations than traditional cold brew methods were observed. This observation was due to flow channeling/detachment phenomena in the coffee bed which resulted in localized flow and reduction of coffee‐water contact area. In comparison, the 30 min full immersion processes resulted in approximately 70% of the TDS, TA, and caffeine levels during the first 30 min of brewing, suggesting that cold brewing processes may not have to be >8 h in length if these are the targeted brew quality indices.Practical applicationsThis study examined the kinetics and physicochemical quality of continuous circulation cold brewing of coffee and compared it to traditional full immersion cold brewing methods. The findings in this study indicated that: (1) The brew recirculation method explored was not on par with traditional full immersion cold brewing methods in terms of extraction yield due to flow channeling issues present in single‐use capsules; (2) The extraction time of traditional cold brewing processes can potentially be shortened on the basis of TDS, TA and caffeine content; (3) The choice of filtration mechanism is significant when considering the extraction yield of a brewing process.
Prestige, Promotion, and Pay
Authors: FERREIRA DANIEL , NIKOLOWA RADOSLAWA 
Published: December 2023

ABSTRACTWe develop a theory in which financial (and other professional services) firms design career structures to “sell” prestigious jobs to qualified candidates. Firms create less prestigious entry‐level jobs, which serve as currency for employees to pay for the right to compete for the more prestigious jobs. In optimal career structures, entry‐level employees (“associates”) compete for better‐paid and more prestigious positions (“managing directors” or “partners”). The model provides new implications relating job prestige to compensation, employment, competition, and the size of the financial sector.