bluuebunny/crossref_metadata_2025_split huggingface dataset:
Patterns and influencing factors of exercise attendance of breast cancer patients during neoadjuvant chemotherapy
Authors: Goldschmidt Siri , Schmidt Martina E. , Rosenberger Friederike , Wiskemann Joachim , Steindorf Karen 
Published: January 2024

Abstract
Background
Performing 2–3 exercise sessions/week may relieve therapy-related side effects of breast cancer patients (BRCA) and improve their quality of life. However, attendance to the exercise sessions is often impaired. Thus, we investigated patterns and possible influencing factors of attendance to an aerobic (AT) or resistance training (RT) intervention in BRCA during neoadjuvant chemotherapy.

Methods
BRCA (N = 122) were randomly allocated to supervised AT or RT twice weekly during neoadjuvant chemotherapy (18 ± 4 weeks). Attendance was calculated individually and group-wise per training week as the percentage of the performed sessions out of the prescribed sessions. Possible influencing factors were investigated using multiple regression analyses.

Results
Mean individual attendance was 44.1% ± 29.3% with no significant differences between the groups. Group-wise attendance was highest in the first 6 weeks of training with ≥ 60% for AT and ≥ 50% for RT, but decreased over the course of the intervention accompanying chemotherapy. Significantly higher attendance was associated with not having vs. having nausea (ß =  − 14.57; p = 0.007) and not having vs. having pain (ß =  − 12.07; p = 0.12), whereas fatigue did not show any association (ß =  − 0.006; p = 0.96). Having been randomized into a preferred intervention group (48.8%) showed no association with attendance. Yet, patients’ rating of the exercise intervention as “good”/ “very good” (58.7%) was significantly associated with higher attendance (p = 0.01).

Conclusion
For both exercise interventions, group-wise attendance/training week decreased during chemotherapy despite good intervention ratings. While some patients never started, others trained almost constantly twice weekly. The study revealed that patients who are nauseous or experience pain may need more support to attend more exercise sessions.
Trial Registration Clinicaltrials.gov: NCT02999074 from May 6, 2016.
Fenfluramine in clinical practice: new therapy option for Dravet and Lennox–Gastaut syndromes
Authors: Muhle Hiltrud , Kurlemann Gerhard , Lehmann Irene , Hamer Hajo , Mayer Thomas , Potschka Heidrun , Schubert-Bast Susanne , Strzelczyk Adam , Pringsheim Milka 
Published: January 2024

AbstractFenfluramine is an antiseizure medication for the treatment of Dravet and Lennox–Gastaut syndromes. This review summarizes the literature on the efficacy and tolerability of fenfluramine and presents recommendations for practical therapeutic management. With regular monitoring, this medication is generally well tolerated and to date has shown no cardiac side effects such as valve insufficiency or pulmonary hypertension in the clinical development program. However, children may experience a loss of appetite and should be closely monitored for weight loss, and sedation was observed in several overweight patients due to rapid dosage titration; therefore, a slower dosage increase than recommended might be needed for children and adults. Drug interactions should be considered before and during therapy, and dosage reductions are necessary when the medication is used in combination with stiripentol. Furthermore, bromide levels could increase with this medication. Contact with the patient or their relatives is important to determine the general state of health, potential movement disturbances, and seizure frequency so as to allow for timely dosage adjustments during the titration phase.
Effect of a Second Promoter on the Performance of a Potassium Doped Silica-Supported Cobalt Catalyst During CO2 Hydrogenation to Hydrocarbons
Authors: Iloy Rama Achtar , Jalama Kalala , Khangale Phathutshedzo R. 
Published: January 2024

AbstractIn this study, the promoting effects of ruthenium, palladium, and copper on the performance of a 15%Co-1%K/SiO2 catalyst were evaluated during CO2 hydrogenation in a fixed-bed reactor. Reactions were carried out at atmospheric pressure and 270 °C with H2/CO2 ratio of 3. All catalysts were characterized by X-ray diffraction (XRD), Brunauer–Emmett–Teller (BET) and temperature-programmed reduction (TPR). Ruthenium, palladium and copper facilitated the reduction of cobalt oxides and increased cobalt dispersion. In terms of catalyst’s performance, ruthenium addition led to increased CO2 conversion and methane selectivity with a detrimental effect on C5+ hydrocarbons. Palladium also presented a similar pattern at lower loading but a drop in CO2 conversion and increased reverse water–gas shift activity were observed at 3 wt % Pd loading. Promoting with copper resulted in decreased activity, methane selectivity and C5+ hydrocarbons productivity with a much higher CO selectivity.
Graphical Abstract
AC-IQuAD: Automatically Constructed Indonesian Question Answering Dataset by Leveraging Wikidata
Authors: Doxolodeo Kerenza , Krisnadhi Adila Alfa 
Published: January 2024

AbstractConstructing a question-answering dataset can be prohibitively expensive, making it difficult for researchers to make one for an under-resourced language, such as Indonesian. We create a novel Indonesian Question Answering dataset that is produced automatically end-to-end. The process uses Context Free Grammar, the Wikipedia Indonesian Corpus, and the concept of the proxy model. The dataset consists of 134 thousand simple questions and 60 thousand complex questions. It achieved competitive grammatical and model accuracy compared to the translated dataset but suffers from some issues due to resource constraints.
The Impact of Various Heating Rates on Real-Time Degree of Hybrid Fire Simulation
Authors: Faghihi Faranak , Knobloch Markus 
Published: January 2024

AbstractGlobal fire performance of structures in fire is proven to be more advantageous in many cases of engineering practice than the prescriptive fire resistance based on isolated structural member testing. Hybrid fire simulation (HFS) is a novel well-suited method trending in recent years for analysis of global performance of structures in fire. In the principles of this method, the part of a structure which has unknown behavior or is uncertain to be numerically modeled (subjected to fire) would be physically tested, while the rest of the structure is numerically simulated. HFS method enables capturing the beneficial interaction mechanisms evolving between fire-exposed structural members and the adjacent cooler substructure. Due to the continuous temperature increase in a fire test and the existing thermal inertia as well as the rate- and temperature-dependent material behavior of structures exposed to fire, a real-time performance in hybrid fire simulation counts as a necessity. This challenge is more critical for hybrid fire simulations with higher applied heating rates relevant to structural fire engineering. Within scope of this paper, (a) a robust and rigorous approach for real-time HFS is presented; (b) a series of proof-of-concept studies of different hybrid fire simulations with various applied heating rates are carried out for a thermomechanical benchmark problem; (c) the important results of four representative hybrid fire simulations with relevant heating rates to structural fire engineering are discussed; (d) the importance of an appropriate calculation method for stiffness update of the fire-exposed structural member over HFS procedure is highlighted, and e) the precision and accuracy of the applied HFS approach with respect to interface error and real-time degree are evidenced.
On bifurcations, resonances and dynamical behaviour in nonlinear iteroparous Leslie matrix models
Authors: Wikan Arild , Kristensen Ørjan 
Published: January 2024

AbstractLeslie matrix models with nonzero nonlinear fecundity elements are under consideration. It is proved that by use of the general Deriso–Schnute recruitment function the supercritical nature of bifurcations in 2- and 3-age class models and a thorough analysis of 1:2 and 1:3 resonance phenomena are also provided. A discussion of impact of coexisting attractors and structures of trapping regions is included as well. Results regarding stabilizing and destabilizing effects as well as dynamical outcomes found in general n-age class models are also presented. Suggestions with respect to where our models may apply are provided too.
Aircraft noise modifies acoustic signals and social interactions of a microendemic frog from Mexico City
Authors: Serrano José Manuel , Ochoa-Ochoa Leticia M. 
Published: January 2024

AbstractResearch on urban noises affecting acoustic communication of animals is a growing area of study and conservation concern. However, the consequences of aircraft noise on anuran acoustic communication have been explored on a restricted basis to date. In this study, we investigated the impact of aircraft overflights on the individual and chorus performance of acoustic signalling in the Pedregal frog (Eleutherodactylus grandis), a microendemic and threatened species from Mexico City. During the summer of 2021, we recorded acoustic signals from male individuals and conducted acoustic monitoring to analyse how chorus social interactions change due to aircraft overflights. For this purpose, we evaluated acoustic properties of the call, including call duration, dominant frequency, call amplitude, and call repetition rate. Additionally, we measured the amplitude of environmental noises and signals by means of two types of complementary methodological approaches. Our results show changes in the individual performance of acoustic signals with longer call duration, lower dominant frequency, and higher call amplitude due to aircraft overflights, while individual call repetition rate did not vary. Furthermore, a decrease in the number of calls within the chorus was observed during aircraft overflight. Overall, these results show that aircraft noise causes plastic changes in the acoustic signals of the Pedregal frog and that social interactions between conspecifics decrease, thus adding a new disturbance to this species that already suffers from other anthropogenic noises, and habitat fragmentation.
A mapping of two spheres: how SEW stimulates the strategic analysis and forecast of a family firm
Authors: Ade Adrian 
Published: January 2024

AbstractThis paper detects valuable research findings at the intersection of socioemotional wealth and strategic decision-making processes. While socioemotional wealth is a key construct in research on family firms, strategic management represents a foundational approach to strategic management processes. The systematic literature review identifies from an extensive sample, a final set of 169 journal articles using a multistep methodology. We perform an in-depth content analysis that highlights the overlap between socioemotional wealth and strategic management. One field of strategic management, namely Analysis & Forecast, offers particular potential for further research. Hence, we create construct clarity by developing five aggregated categories. These categories act as dimensions of an integrative framework with strategic analysis activities. The literature review leads to the conclusion that in previous research, each socioemotional wealth dimension influences every analysis activity but one at a time.
Cost accounting practices in SMEs: liability of age and other factors that hinder or burst its implementation in turbulent years
Authors: Roffia Paolo , Benavides María Mar , Carrilero Augustin 
Published: January 2024

AbstractThis study aimed to investigate the level of cost accounting (CA) implementation in small- and medium-sized enterprises (SMEs). CA is a management accounting tool whose application in small companies has always been difficult. Nevertheless, academicians and practitioners recommend CA implementation in SMEs, especially because of the deep market instability, competitive pressure, and margin erosion that have occurred following the COVID-19 pandemic and 2022 European war scenario. Company size influences CA implementation; however, it is not the only influencing factor and perhaps not even the most important. To investigate the barriers to the adoption of CA and which conditions or actions can remove these barriers, leveraging from the contingency theory, a questionnaire was sent out in July 2022 to limited liability SMEs operating in the manufacturing, construction, and distribution macro-sectors in Verona and Vicenza provinces (Italy). Respondents answered a set of questions regarding CA implementation in their SMEs as of July 2022. Using a multivariate regression model to analyze data from the 120 questionnaires received, we found that lack of resources, limited training and skills, firm age, and the presence of the founder in the firm had a negative influence on CA implementation in SMEs. The low level of CA implementation was also associated with its supposed inefficiency, uselessness, and unsuitability for business. The effect of company size on CA implementation was not statistically significant. Despite this study’s limitations regarding the sample and period considered, we believe that it contributes to both academic debates and practice by illustrating the limiting factors and ways in which CA implementation can be fostered in SMEs in turbulent years.
Can security be sustainable? Three perspectives on security and social sustainability: paradox, co-production, and deconstruction
Authors: Malmio Irja 
Published: January 2024

AbstractSecurity and sustainability are prioritized goals in the “Western liberal” world. Maintaining democratic resources while simultaneously strengthening society’s ability to deal with security issues firmly resonates with ideals associated with social sustainability. However, merging normative theories like security and social sustainability produces conceptual difficulties that are hard to resolve. Based on key literature in this field and policy documents from the UN, this article uses conceptual analysis to investigate what boundaries and openings three distinct perspectives of the connection between social sustainability and security might produce. The perspectives chosen as illustrative tools are paradox, co-production, and deconstruction. The paradox perspective pronounces inherently divergent qualities of sustainability and security, which implies a trade-off situation. In contrast, the co-production perspective views social sustainability as a critical component in security issues, while security, in turn, is a prerequisite for sustainability. A third perspective, deconstruction, highlights underlying processes that produce and prioritize specific meanings. The perspectives of paradox, co-production, and deconstruction identify how competing values operate in conceptual configurations, highlighting the limitations and possibilities of security measures to accommodate values of social sustainability. Applying distinct approaches as illustrations for disparate ideological standpoints can deepen the knowledge of how multiple and occasionally competing outcomes are formed while considering the normative foundations enfolding inquiries of security responses to societal challenges.
Low-hit-zone frequency hopping sequence sets under aperiodic Hamming correlation
Authors: Liu Xing 
Published: January 2024

AbstractThe study of aperiodic Hamming correlation (APC) of frequency hopping sequences (FHSs) is a hard problem that has not been paid enough attention in the literature. For low-hit-zone (LHZ) FHSs, the study of APC becomes more difficult. We call them LHZ FHSs under APC (LHZ-APC FHSs). LHZ-APC FHSs are studied for the first time in this paper. First, we establish a bound on the family sizes of LHZ-APC FHS sets. Then we present a method for constructions of LHZ-APC FHS sets based on conventional FHS sets under periodic Hamming correlation (conventional PC FHS sets). By choosing different conventional PC FHS sets, we obtain three classes of LHZ-APC FHS sets whose family sizes are optimal or near optimal according to this new bound. Further, we modify the construction method and get more new LHZ-APC FHS sets with optimal family sizes.
Characteristics and prognosis of patients with COVID-19 and hematological diseases in Japan: a cross-sectional study
Authors: Minakata Daisuke , Uchida Tomoyuki , Nakano Aya , Takase Ken , Tsukada Nodoka , Kosugi Hiroshi , Kawata Eri , Nakane Takahiko , Takahashi Hiroyuki , Endo Tomoyuki , Nishiwaki Satoshi , Fujiwara Hideaki , Saito Akiko M. , Saito Toshiki I. , Akashi Koichi , Matsumura Itaru , Mitani Kinuko 
Published: January 2024

AbstractThe Japanese Society of Hematology performed an observational cross-sectional study to clarify the morbidity, prognosis, and prognostic factors in patients with COVID-19 with hematological diseases (HDs) in Japan. The study included patients with HDs who enrolled in our epidemiological survey and had a COVID-19 diagnosis and a verified outcome of up to 2 months. The primary endpoints were characteristics and short-term prognosis of COVID-19 in patients with HDs. A total of 367 patients from 68 institutes were enrolled over 1 year, and the collected data were analyzed. The median follow-up among survivors was 73 days (range, 1–639 days). The 60-day overall survival (OS) rate was 86.6%. In the multivariate analysis, albumin ≤ 3.3 g/dL and a need for oxygen were independently associated with inferior 60-day OS rates (hazard ratio [HR] 4.026, 95% confidence interval (CI) 1.954–8.294 and HR 14.55, 95% CI 3.378–62.64, respectively), whereas 60-day survival was significantly greater in patients with benign rather than malignant disease (HR 0.095, 95% CI 0.012–0.750). Together, these data suggest that intensive treatment may be necessary for patients with COVID-19 with malignant HDs who have low albumin levels and require oxygen at the time of diagnosis.
Influence of Guidance on Occupational Image and Traineeship’s Satisfaction of Vocational Students
Authors: Dubeau Annie , Chochard Yves 
Published: January 2024

AbstractInitial vocational training (VT) in high school consists of short-term programs leading to employment in a skilled trade. To better align training with employment opportunities and to encourage students to stay in the programs until they graduate, most programs include traineeship. Since traineeships involve acquiring skills directly on the job, they require greater involvement of supervisors to guide the trainees. Given the importance of on-the-job guidance in achieving traineeship objectives, this study examines the potential influence of three dimensions of guidance provided by traineeship supervisors –planning, support, and training– on students’ job perception (i.e., occupational image) and traineeship satisfaction. Overall, the results provide mixed results, partially supporting the mediation hypothesis suggested by the results of previous studies. Indeed, the results reveal that the quality of the training offered by the supervisor affects subsequent students’ satisfaction with traineeship experience. Training has an indirect effect on satisfaction via the occupational image held by students. However, the expected indirect links between the other two dimensions of supervisor guidance –degree of planning and support perceived by the student– and the students’ image of their chosen occupation could not be confirmed. The results support the importance of providing quality on-the-job training to students during their studies.
SARS-CoV and SARS-CoV-2 display limited neuronal infection and lack the ability to transmit within synaptically connected axons in stem cell–derived human neurons
Authors: Luczo Jasmina M. , Edwards Sarah J. , Ardipradja Katie , Suen Willy W. , Au Gough G. , Marsh Glenn A. , Godde Nathan , Rootes Christina L. , Bingham John , Sundaramoorthy Vinod 
Published: January 2024

AbstractSarbecoviruses such as SARS and SARS-CoV-2 have been responsible for two major outbreaks in humans, the latter resulting in a global pandemic. While sarbecoviruses primarily cause an acute respiratory infection, they have been shown to infect the nervous system. However, mechanisms of sarbecovirus neuroinvasion and neuropathogenesis remain unclear. In this study, we examined the infectivity and trans-synaptic transmission potential of the sarbecoviruses SARS and SARS-CoV-2 in human stem cell–derived neural model systems. We demonstrated limited ability of sarbecoviruses to infect and replicate in human stem cell–derived neurons. Furthermore, we demonstrated an inability of sarbecoviruses to transmit between synaptically connected human stem cell–derived neurons. Finally, we determined an absence of SARS-CoV-2 infection in olfactory neurons in experimentally infected ferrets. Collectively, this study indicates that sarbecoviruses exhibit low potential to infect human stem cell–derived neurons, lack an ability to infect ferret olfactory neurons, and lack an inbuilt molecular mechanism to utilise retrograde axonal trafficking and trans-synaptic transmission to spread within the human nervous system.
Influence of pillar wide and room’s height on the acoustic emission phenomena during crack evolution
Authors: Rezaei Amir , Sarfarazi Vahab , Babanouri Nima , Omidi manesh Mohammad , Bahrami Reza , Wang Xiao 
Published: January 2024

AbstractThe present study probes the effects of pillar wide and room’s height on the failure mechanism of model using experimental test and numerical simulation. For this purpose, firstly gypsum specimens with dimension of 15*15*5 cm containing two neighboring rooms and one pillar were prepared. Pillar widths were 3 cm, 6 cm and 9 cm. In each pillar width, the roof height was 1 cm, 2 cm, 3 cm, 4 cm, 5 cm, and 6 cm. Totally 9 physical specimens were tested. Concurrent with experimental tests, 18 numerical models were simulated. The results show that the pillar wide and roof height affect the failure pattern and compressive strength of models. Two different failure patterns were observed in the model. In the first stage, two tensile fractures were developed from room edge and propagated parallel to loading axis till coalescence with model boundary. In the second stage, mixed tensile-shear cracks were developed through the rock pillar. It is shown that with the augment of stress–strain curve until the peak, the AE hits of numerical specimens presents three stages. In the first stage, AE hits is almost zero; this step is in the elastic stage, and there isn’t any crack in the sample. In the second stage, AE hits is in a slowly increasing stage, which is due to the micro cracks in the model continuous expansion. In the third stage, the AE hits increase rapidly, because the rock almost enters its bearing limit and the crack propagation speed is very fast. Generally, the maximum value of AE is near the peak value. When the roof height is the same, different pillar wide led to a significant change in the maximum AE hits. The experimental test and numerical simulation show the similar outcomes.