bluuebunny/crossref_metadata_2025_split huggingface dataset:
Refocusing research: A mixed methods study to evaluate utilisation of the top 10 priorities for occupational therapy research in the United Kingdom
Authors: Martin Aleysha Kate , Ward Gillian 
Published: February 2024

Introduction: The top 10 priorities for occupational therapy research in the United Kingdom were identified via a priority setting partnership and published in 2020. This study aimed to evaluate utilisation of the top 10 priorities since 2020 and identify recommendations to re-focus research efforts. Method: A mixed methods approach involving evidence checking and stakeholder consultation was undertaken. Direct and selective methods were used to recruit stakeholders, including previous steering group members, who were invited to take part in 30-minute semi-structured interviews. Results: Eighty-one evidence sources were included and addressed the research priorities 127 times. Stakeholders ( N = 7) discussed the top 10 priorities in relation to five key themes: (1) what has been done; (2) the most addressed priorities; (3) the least addressed priorities; (4) barriers to using the priorities (three barriers emerged); and (5) what should be done next (six strategies emerged). Conclusion: There was strong agreement that research priority 1 (how does occupational therapy have an impact and make a difference on everyday lives?) was the most addressed; however, all research priorities require more attention. Recommendations to refocus research efforts included continuing to support priority-driven research and greater promotion of the priorities.
Polyetheretherketone Polymer Transpedicular Vertebral System to Treat Vertebral Compression Fracture: A Multicentre Pilot Study of Feasibility and Safety
Authors: Barral Matthias , Razakamanantsoa Léo , Tselikas Lambros , De Baere Thierry , Le Huec Jean-Charles , Cornelis Francois H. 
Published: February 2024

Objectives: To prospectively evaluate the feasibility and safety of a polyetheretherketone (PEEK) polymer transpedicular vertebral system to treat vertebral compression fracture (VCF). Methods: Nine consecutive patients (4 men and 5 women; median age 59 [interquartile range: 58-64 years]) were included. The procedure duration, length of hospital stay, and complications were reported. Visual analog scale (VAS) and the Oswestry disability index (ODI) for pain and disability were assessed before and at 2, 6, and 12-month after the procedure. Results: The procedure was technically feasible in all patients. The median procedural time was 64 minutes [45-94]. Only minor adverse events were reported (5 clinically asymptomatic cement leakages) but no severe complications. No post procedural adjacent fracture was reported during follow-up (median: 193 days [147-279]). The median VAS score decreased from 55 mm [50-70] before the procedure to 25 mm [5-30] at 2-month ( P = .0003) and 30 mm [15-40] at 6-month follow-up ( P = .14). The median ODI decreased from 23% [19-26] before the procedure to 12% [10-14] at 2-month ( P = .03) and 12% [9-20] at 6-month follow-up ( P = .47). Conclusion: Percutaneous transpedicular fixation of VCF by PEEK implants appears feasible and safe.
COVID-19 Diagnosis, Severity, and Long COVID Among U.S. Adolescents, National Health Interview Survey, 2022
Authors: Nguyen Kimberly H. , Chen Siyu , Bao Yingjun , Lu Yang , Bednarczyk Robert A. , Vasudevan Lavanya 
Published: February 2024

Purpose Understanding disparities in COVID-19 outcomes, overall and stratified by vaccination status, is important for developing targeted strategies to increase vaccination coverage and protect adolescents from COVID-19. Design The 2022 National Health Interview Survey (NHIS) is a cross-sectional nationally representative household survey of U.S. adults. Setting A probability sample of households in the U.S. Sample One child aged 12-17 years is randomly selected from each family in the household. A knowledgeable adult (eg, parent or guardian), responds on behalf of the child through an in-person interview (response rate = 49.9%). Measures Input measures-sociodemographic characteristics and COVID-19 vaccination status; output measures-ever had COVID-19, moderate/severe COVID-19, long COVID Analysis Prevalence of COVID-19 outcomes was assessed for adolescents aged 12-17 years. Factors associated with each COVID-19 outcome were assessed with multivariable logistic regression analyses. Results Among 2758 adolescents aged 12-17 years in 2022, 60.5% had received ≥1 dose of COVID-19 vaccine, 30.2% had ever been diagnosed by a doctor that they had COVID-19, 29.5% had moderate/severe COVID-19, and 6.2% had long COVID. Adolescents who were vaccinated with ≥1 dose were less likely to be diagnosed with COVID-19 (aOR = .79) and less likely to have long COVID (aOR = .30). Conclusion Targeted messaging to highlight the importance of early treatment, the harms of long COVID-19, and the benefits of vaccination in protecting against long-term effects may be necessary to ensure that all adolescents and their families are adequately protected.
Effect of meta-structure on mechanical properties of polyvinylidene fluoride composite-based 3D printed intramedullary pins
Authors: Husain Minhaz , Singh Rupinder , Pabla Bahadur Singh 
Published: February 2024

Some studies have outlined the use of 3D-printed polyvinylidene fluoride (PVDF) composite-based solid intramedullary (IM) pins with tunable mechanical (tensile, compressive, flexural, and torsional) properties for orthopedic applications. But hitherto little has been reported on the effect of meta-structure induced in 3D-printed IM pins for canines from the mechanical properties’ viewpoint. This study highlights the design, fabrication, and testing to mimic actual loading conditions in the canine femur bone on novel IM pin with meta-structure employed in different length zones (30%, 40%, and 50% of total gauge length) prepared by fused filament fabrication (FFF) of PVDF composite. The IM pin (of length 150 mm) has square threads (pitch 2 mm) at the distal end (ɸ7 mm, up to 60 mm in length), and V threads (pitch 1.5 mm) at the proximal end (ɸ6 mm, up to 30 mm in length). The IM pin was fabricated at the best setting (of the FFF process) suggested by the multifactor optimization (at nozzle temperature (Nt) 235°C, printing speed (Ps) 60 mm/s, and raster angle (RA) 45°). The result suggests that for the solid IM pins prepared at the optimized settings the observed elongation, peak load (PL), and break load (BL) during tensile and compressive loading were 4.83 mm, 968.40 N, 958.20 N, and 14.19 mm, 412.80 N, 371.52 N respectively. Whereas for 50% meta-structure the observed elongation, PL, and BL during tensile and compressive loading were 14.49 mm, 405.49 N, 90.20 N, and 13.23 mm, 243.20 N, 218.88 N respectively. For both tensile and compression loading (in this case study), better elongation was noticed for the FFF-based IM pin with 50% meta-structure and hence recommended for implantation in the canine femur bone. The results are also supported by scanning electron microscopy (SEM), and energy dispersive spectroscopy (EDS) based surface characteristics of the fracture sites.
Tell Me an Instagram Story: Ephemeral Communication and the 2018 Gubernatorial Elections
Authors: Towner Terri L. , Muñoz Caroline L. 
Published: February 2024

Political campaigns are embracing the visual social media platform Instagram. One digital feature, the Story, has taken over feed sharing across social media. A Story is a sequence of images or videos uploaded to a profile that disappear after 24 hours. The Story is a novel feature relatively unexamined in political communications and marketing research. Specifically, it is unclear how Gubernatorial candidates employ the Instagram Story feature in campaigning. To address this gap, we content analyze 730 Instagram Stories drawn from 20 Gubernatorial candidate accounts one week before and after Election Day 2018. Results reveal that over half of the candidates employed the Story feature over the two-week period. The Story content primarily included indoor rallies and speeches rather than outdoor canvassing. Campaigns featured more static images than video in Stories and rarely used interactive features, such as animation, location tags, and emojis. Stories were also geared toward mobilization messages rather than voter support, behind-the-scenes looks, and attack ads. Last, some gender and political party differences were evident, as women and Democratic candidates utilized Instagram more.
Systemic lupus erythematosus following COVID-19 vaccination. A systematic review of case reports and case series
Authors: Cahuapaza-Gutierrez Nelson Luis 
Published: February 2024

Objective Vaccination against SARS-CoV-2 reduced morbidity and mortality rates due to COVID-19 worldwide. However, several adverse effects have been documented and of great interest such as Systemic Lupus Erythematosus (SLE). The aim of the present study was to perform a systematic review of case reports and case series describing the development of SLE following COVID-19 against vaccination. Methods Case report and case series studies were included. Systematic reviews, narratives, letters to the editor, correspondence, etc. were excluded. A selective bibliographic search was performed in the PubMed, Scopus, and EMBASE databases. In addition, the Web of Science platform was consulted. The Joanna Brigs Institute (JBI) tool was used to assess the risk of bias and quality of the studies. The Statistical Package for the Social Sciences (SPSS) 23.0 was used for the formal analysis of the descriptive data. Results 12 studies met the eligibility criteria and reported a total of 16 patients. The mean age was 42.4 ± 18.69 years. A slight predominance of post-vaccination SLE was observed in females (females ( n = 9) and males ( n = 7). A higher association was found with Pfizer-BioNTech-162b2 vaccine (75%), followed by Sinopharm (12.5%), Moderna (6.25%). and AstraZeneca (6.25%) vaccines. Most cases were associated with the first dose (56.25%), followed by the second dose (37.5%) and only one case associated with the third dose. The number of days elapsed from vaccine administration to the appearance of the first clinical manifestations was between 1 and 30 days. Mainly there was involvement of the musculoskeletal and cutaneous system. All patients responded well to treatment with good evolution and there was no case of death. Conclusion Cases of SLE associated with COVID-19 vaccination against are infrequent. However, clinical monitoring is recommended for persons receiving the SARS-CoV-2 vaccine, mainly those receiving the first dose and the Pfizer-BioNTech-162b2 vaccine.
Moral sensitivity and academic ethical awareness of nursing and medical students: A cross-sectional survey
Authors: Ko Yuet Kiu , Cho Cordelia , Sun Sihan , Ngan Olivia MY , Chan Helen YL 
Published: February 2024

Background Moral sensitivity and academic integrity discernment hold paramount importance for healthcare professionals. Owing to distinct undergraduate educational backgrounds, nurses and physicians may exhibit divergent moral perspectives, academic integrity cognisance, and moral sensitivity within clinical environments. A limited number of studies have investigated the disparities and congruencies pertaining to moral sensitivity and academic ethical awareness among nursing and medical students. Objective The study compares moral sensitivity and academic ethical awareness of undergraduate nursing and medical students with and without clinical exposure. Research design A self-administered cross-sectional survey conducted from January to February 2022 was used to collect data from a medical school in Hong Kong. Participants and research context A total of 545 respondents, including 137 nursing students and 408 medical students, completed the questionnaire. Ethical consideration Ethics approval of the study was obtained. Written consent was waived to maintain anonymity because completing the questionnaire was considered implied consent. Findings Both groups of undergraduates demonstrated a high level of bioethics knowledge. In terms of academic integrity, medical students were found to have a less concerned attitude towards punctuality, attendance, and skipping classes. Regarding moral sensitivity, senior medical students with clinical experience put less emphasis on decision-making involving patient participation, while senior nursing students were more hesitant in withholding treatment for incompetent patients who refused treatment. Both nursing and medical students showed decreased moral sensitivity in the ‘conflicts’ domain with increased clinical exposure. Conclusion Study findings contribute to the discussion comparing the ethical attitudes of nursing and medical students. More effort should be made in nursing and medical education to promote practices in line with high academic integrity and to develop the ability to be morally sensitive in professional settings.
Quality Initiative Program to Improve the Percentage of Very Preterm Neonates Receiving Expressed Breast Milk Within 24 Hours of Birth in a Tertiary Care (Level III-B) NICU
Authors: Minj Grace Mary , Narayanaswamy Vindhya , Nagesh Karthik 
Published: February 2024

Background There is often a delay in the initiation of feeding in preterm babies and more dependence on PDHM milk due to the non-availability of the mother’s own milk. This study aimed to increase the percentage of very preterm neonates receiving expressed breast milk (EBM) within 24 hours of birth. Methods A quality improvement (QI) initiative study was conducted from May 2022 to August 2022 in a tertiary care (Level III-B) NICU. A QI support team was formed. The reasons for the delay in the initiation of expression of breastmilk were evaluated. We included preterm neonates (<32 weeks gestation) born within the study period. Antenatal and postnatal counseling regarding the expression of breast milk, using leaflets and video, frequent visits, telephonic reminders, and emphasizing Kangaroo Mother Care through various Plan-Do-Study-Act cycles were done. Results A total of 17 very preterm babies were studied over a period of 3 months. The percentage of preterm receiving EBM within 24 hours of birth, increased from 20% (observation phase) to 83.3% (initiation phase) and maintained to 90% in the continuation phase. The time of receiving the first EBM reduced from a median of 32.5 hours (1.35 days) in the retrospective phase to 17 hours (0.7 days) during the initiation phase and it was sustained later on. Mothers were able to express as early as within 4.5 hours. Conclusion A simple QI intervention showed early expression and sustenance of breast milk in mothers of preterm neonates.
Backing plate material selection for optimizing joint performance in friction stir welded aluminium honeycomb
Authors: Dutta Ananta , Pal Surjya K , Panda Sushanta K 
Published: February 2024

Aluminium honeycomb core is a thin-walled cellular structure extensively used in crash resistance applications in automotive industry. To overcome current challenges in adhesive-bonded honeycomb, new fabrication route using micro friction stir lap welding has been proposed. With a specific energy absorption capacity as high as 28.2 kJ/kg in flatwise impact testing, fabricated honeycomb demonstrated its potential for industrial applications. The structure exhibited no weld cracks or cell wall delamination, unlike adhesive-bonded honeycombs. However, in friction stir welding of thin sheets (0.5 mm), achieving an optimized heat input is challenging due to limited scope for variation in process parameter and tool design. Therefore, control of heat outflow by proper selection of backing plate material is the alternative approach for achieving desirable joint performance. Experiments with backing plates having a range of thermal diffusivities demonstrated that joint produced with mild steel backplate exhibited maximum shear-tensile strength. Conversely, joint with aluminium backplate exhibited poor plastic flow of material. Effective sheet thickness and lap width were predominantly affected by heat accumulation in weld, resulting in different failure modes.
The Utility of 18F-FDG-PET–CT Metabolic Parameters in Evaluating the Primary Tumor Aggressiveness and Lymph Node Metastasis of Nasopharyngeal Carcinoma
Authors: Zhang Yun , Hu Yuxiao , Zhao Shuang , Huang Rong 
Published: February 2024

Background: Following changes in primary tumor (T) and lymph node (N) staging for nasopharyngeal carcinoma (NPC) in the Eighth Edition AJCC Cancer Staging Manual, simplification of T staging has been proposed. However, a limited range of 2-deoxy-2-[fluorine-18] fluoro-D-glucose positron emission tomography–computed tomography (18F-FDG PET–CT) metabolic parameters has been investigated. Therefore, we aimed to evaluate the primary tumor invasiveness and the lymph node metastasis (LNM) of NPC from a metabolic perspective. Methods: A total of 435 NPC patients underwent 18F-FDG PET/CT before treatment were retrospectively examined. The primary endpoint was differences in standard uptake value (SUV), lean body mass-normalized SUV (SUL), body surface area-normalized SUV (SUS), glucose-normalized SUV (GN), metabolic tumor volume (MTV), total lesion glycolysis (TLG), and glucose-normalized total lesion glycolysis (GNTLG) of primary tumors and LNM between different T and N stages. The metabolic parameters associated with T and N staging were identified. Results: There were significant differences between all parameters relative to the primary tumor but no significant differences in any parameter relative to the LNM and T stages. Higher mean values of TGNmax, TGNmean, TSUVpeak, and TSUSmax were associated with advanced T stages. Higher mean values of all the LNM parameters were associated with more advanced N stages. Only primary tumor metabolic tumor volume (TMTV), TSUVpeak, TSULmax, and TSUSmax showed a significant positive association with T staging, while lymph node metabolic tumor volume (LNMTV) and TSUSmax were significantly positive in N staging. Conclusions: Our findings suggest that metabolic parameters are useful indicators of tumor invasiveness and LNM based on the Eighth Edition manual. Compared with volume-dependent parameters, TGNmax, TGNmean, TSUVpeak, and TSUSmax may be better indicators of local tumor aggressiveness. SUSmax of the primary tumor was associated with LNM. In addition to SUVmax, other metabolic parameters (eg, SULmax, SUSmax, GNmax, and GNmean) could evaluate tumor aggressiveness and LNM better.
Verrulyse Methionine® as Monotherapy in Children and Adolescents With Common Warts
Authors: Friedland Rivka , Renert-Yuval Yael , Solomon-Cohen Efrat , Reiss-Huss Shiran , Ben Amitai Dan 
Published: February 2024

Background: Common cutaneous non-genital viral warts are a common skin infection with significant morbidity in the pediatric population. Although various therapeutics are available, many of them necessitate recurrent patient visits and may be associated with significant irritation and pain. Verrulyse Methionine® (VM), a nutritional supplement, was previously suggested as a non-invasive treatment option for the disease. Objective: To assess the response to oral VM supplement as a monotherapy in a cohort of children and adolescents with multiple, non-genital viral warts after failing previous treatments. Methods: We reviewed medical records of pediatric patients (<18 y/o) with viral warts treated with VM between 2010 and 2021. Results: Among 25 patients with multiple verrucae vulgaris lesions who failed previous treatments, 14 (56%) had complete or almost-complete response to VM within 4 months, after an average of 18 months of active disease prior to VM treatment initiation. None of the 4 patients with verruca plana had response to VM treatment. Favourable cosmetic results were found in responders, and no adverse events were recorded. Conclusion: Response rates in our cohort are comparable to those reported in the literature for destructive local therapeutics for viral warts. Thus, our data suggest that VM may be considered for children with multiple verrucae vulgaris, providing a painless and non-invasive therapeutic option for this common disease.
Mortality risk among Autistic children and young people: A nationwide birth cohort study
Authors: Vu Hien , Bowden Nicholas , Gibb Sheree , Audas Richard , Dacombe Joanne , McLay Laurie , Sporle Andrew , Stace Hilary , Taylor Barry , Thabrew Hiran , Theodore Reremoana , Tupou Jessica , Schluter Philip J 
Published: February 2024

Autism has been associated with increased mortality risk among adult populations, but little is known about the mortality risk among children and young people (0–24 years). We used a 15-year nationwide birth cohort study using linked health and non-health administrative data to estimate the mortality risk among Autistic children and young people in Aotearoa/New Zealand. Time-to-event analysis was used to determine the association between autism and mortality, controlling for sex, age, ethnicity, deprivation and rurality of residence. The participant population included 895,707 children of whom 11,919 (1.4%) were identified as Autistic. Autism was associated with a significantly higher mortality risk (hazard ratio = 2.35; 95% confidence interval = 1.80–3.06) compared to the general population. In addition, using stratified analyses, we found that this risk was significantly higher among females (hazard ratio = 5.40; 95% confidence interval = 3.42–8.52) compared to males (hazard ratio = 1.82; 95% confidence interval = 1.32–2.52). We also determined that among Autistic young people, mortality risk was significantly higher for those with a co-occurring intellectual disability (hazard ratio = 2.02; 95% confidence interval = 1.17–3.46). In this study, autism was associated with higher mortality in children and young people compared to the non-Autistic population. Increased efforts are required to better meet the health needs of this population. Lay abstract Existing literature indicates that Autistic people have shorter life expectancy, but little is known about the mortality risk among Autistic children and young people (0–24 years). We used a 15-year nationwide birth cohort study to estimate the mortality risk among Autistic children and young people in Aotearoa/New Zealand. The study included 895,707 children and 11,919 (1.4%) were Autistic. We found that autism was associated with a significantly higher mortality risk compared to the non-Autistic population. In addition, we found that this risk was significantly higher among females compared to males and for those with a co-occurring intellectual disability. Increased efforts are required to better meet the health needs of this population.