bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ankylosing spondylitis impact on knee cartilage thickness: correlation with demographic data and clinical characteristics
Authors: Adel Omnia R. , Kamel Shereen R. , Mohamed Fatma A. , El Ameen Nadia F. , Darwish Ayman F. 
Published: November 2023

Abstract
Background
Ankylosing spondylitis (AS) is a progressive inflammatory disease involving cartilaginous structures in the spine and peripheral joints. However, the number of the studies assessing knee cartilage thickness in AS and its correlations with parameters of disease activity/severity is even less. We aimed to assess the impact of AS on knee cartilage thickness using musculoskeletal ultrasound (MSUS) and magnetic resonance imaging (MRI).

Methods
Twenty-five AS patients and 25 healthy individuals (15 served for MSUS assessment, and 10 served for MRI assessment) were included. By employing MRI “using a 1.5-T machine” and MSUS “with a 10–18-MHz linear probe,” respectively, the thickness of the femorotibial cartilage and femoral cartilage was assessed.

Results
Compared to healthy controls, AS patients showed statistically significantly thinner cartilage thickness (P < 0.05) at all femorotibial cartilage subdivisions and the medial femoral condyle and intercondylar area on both sides. Femoral cartilage thickness measurements either assessed by MSUS or MRI were negatively correlated with age, measures of disease activity, and Bath Ankylosing Spondylitis Radiology Index for the spine (BASRI-s) (P < 0.05). However, MRI tibial cartilage thickness was negatively correlated with disease duration and measures of spinal mobility, functional limitation, and BASRI-s (P < 0.05). MRI total cartilage thickness measurements at the femoral condyle were negatively correlated with Bath Ankylosing Spondylitis Functional Index (BASFI) and Ankylosing Spondylitis Disease Activity Score-erythrocyte sedimentation rate (ASDAS ESR) (P = 0.04 and P = 0.03, respectively). A positive correlation was found between MSUS and MRI total femoral cartilage thickness (P = 0.02).

Conclusions
The knee cartilage thickness of AS patients was thinner than that of healthy controls. The correlations between cartilage thickness and patient variables demonstrate MSUS and MRI's utility in identifying knee cartilage loss areas in AS patients.
An interesting case report of delayed presentation of post-cholecystectomy benign biliary stricture
Authors: Haldeniya Kulbhushan , Gandhi Niranjan Rajkumar , Gorantla Haritha , Bukka Sindhura 
Published: November 2023

AbstractBackground The most common cause of benign biliary stricture is bile duct injury after cholecystectomy. Benign biliary strictures are associated with a broad spectrum of signs and symptoms, ranging from subclinical disease with mild elevation of liver enzymes to complete obstruction with jaundice, pruritis, and cholangitis ultimately leading to biliary cirrhosis. The average duration for stricture development after cholecystectomy is around 7 months. This is a case report of a benign biliary stricture presenting 14 years after laparoscopic conversion to open cholecystectomy without the development of recurrent cholangitis and secondary biliary cirrhosis.
A novel ANFIS-controlled customized UPQC device for power quality enhancement
Authors: Srimatha S. , Mallala Balasubbareddy , Upendar J. 
Published: November 2023

AbstractPower quality is crucial for the reliable and efficient operation of domestic and industrial loads. Nonlinear power electronic converter loads have increased in usage, which has led to a decline in both voltage and current quality. To overcome these power quality issues, a universal power quality compensator (UPQC) has been developed and integrated into the power distribution network. The UPQC comprises dual active power filters which are equipped with a DC-link capacitor. The voltage of the DC-link capacitor is controlled by a DC-link voltage controller. However, the conventional PI controller is not suitable for regulating voltage at a defined level due to inappropriate gain values. In this work, we propose an intelligent adaptive neuro-fuzzy inference system-based DC voltage controller for customized UPQC devices. The proposed control scheme aims to mitigate the existing power quality challenges by reducing the issues in classical controllers and incorporating intelligence knowledge with subjective decisions. Using the MATLAB/Simulink software tool, we have tested a customized UPQC device controlled by ANFIS for critical operation and performance. The simulation results are presented along with valid comparisons.
Development of novel gradient RP-HPLC method for separation of dapagliflozin and its process-related impurities: insight into stability profile and degradation pathway, identification of degradants using LCMS
Authors: Sunkara Bhawani , Tummalapalli Naga Venkata Ganesh Kumar 
Published: November 2023

Abstract
Background
In the dapagliflozin (DPF) synthesis, 5-Bromo-2-chlorobenzoic acid (5-BC impurity) and 4-Bromo-1-chloro-2-(4-ethoxybenzyl) benzene (4-BC impurity) are used as starting and reagent sources, respectively. The presence of 5-BC and 4-BC impurities in DPF could potentially affect the effectiveness of the final DPF product. The purpose of this investigation was to develop a stability indicating HPLC methodology for the separation of DPF, its process-related impurities and degradants. The method of analysis was developed on Xbridge Phenyl C18 column of dimensions, 250 × 4.6 mm, 5 μm with gradient elution using mobile phase made up of 0.05% aqueous trifluoroacetic acid and acetonitrile (AcN).

Results
The method proposed indicates a good linearity (R2 = 0.9996 and 0.9993), good system precision (RSD ≤ 2%), good method precision (RSD ≤ 2%), accuracy (50–150%), LOD (0.000053 ppm and 0.0000165 ppm) and LOQ (0.00016 ppm and 0.00005 ppm) for 4-BC impurity and 5-BC impurity, respectively. LC–MS was used to detect and characterise degradants that were obtained in acid and base condition were identified and characterised. A comparison of the fragmentation pattern of the [M + H] + ions of DPF and its degradation products revealed the most likely processes for the generation of degradation products.

Conclusion
DPF sample quality can be evaluated using the suggested method for the presence of 4-BC impurity, 5-BC impurity and 2-(3-(4-ethoxy benzyl)-4-chloro phenyl)-tetrahydro-6-(hydroxy methyl)-2H-pyran-3,4,5-triol.
Resection of infected bulla associated with isolated unilateral absence of pulmonary artery: a case report
Authors: Kusano Megumi , Sakai Takashi , Yoshizawa Takahiro , Koezuka Satoshi , Azuma Yoko , Kishi Kazuma , Iyoda Akira 
Published: November 2023

Abstract
Background
A unilateral absence of the pulmonary artery (UAPA) is a rare congenital anomaly, which in most patients is associated with congenital cardiovascular abnormalities. Some patients with UAPAs do not have associated cardiovascular abnormalities, called isolated UAPA. Patients with isolated UAPA generally have a mild clinical course and may not be diagnosed until adulthood, but repeated complications such as infections may make surgery difficult.

Case presentation
A 34-year-old female patient with isolated right UAPA was referred to our hospital with a complaint of fever. Chest radiography and computed tomography showed an infectious cavity in the right upper lung. Surgery was scheduled for the patient; however, her preoperative condition needed to be optimized. She was evaluated for pulmonary hypertension and the collateral arteries were mapped out, and a waiting period after treatment of infection was set to avoid perioperative intrathoracic infections. Resection of the infected bulla was performed without any complications. No recurrence of infection was observed two years post-operatively. The residual lung expanded enough to fill the dead intrathoracic space.

Conclusions
This report suggests the importance of adequate preoperative evaluation and perioperative management for patients with isolated UAPA who require surgical resection.
Robust Q-compensated multidimensional impedance inversion using seislet-domain shaping regularization
Authors: Li Chao , Liu Guochang , Wang Zhiyong , Shi Lanting , Wu Qibin 
Published: November 2023

Acoustic impedance (AI) inversion plays a vital role in seismic interpretation because AI contains valuable information on lithology and contributes to reservoir characterization. However, the effect of anelastic attenuation dissipates the energy and distorts the phase of seismic waves during their propagation in the earth. Such attenuation-induced effects will degrade the quality of AI inversion unless some preprocessing routines are performed in advance (e.g., inverse Q filtering). In order to invert for AI from nonstationary seismic data directly and enhance the lateral continuity, we have developed a robust Q-compensated multidimensional AI inversion method. The proposed method incorporates the Q-filtering operator into the conventional convolution model and provides an improved iteration scheme, which can avoid some of the errors introduced by those compensation-related processing routines. Furthermore, with the help of seislet nonlinear shaping regularization, the proposed method can accelerate the convergence rate during inversion and further improve the lateral continuity and accuracy of the final inverted results in the presence of noise. Synthetic and field data have been used to validate the effectiveness and robustness of the proposed method. The results demonstrate that compared with the conventional method, the proposed method can retrieve AI from nonstationary seismic data directly with improved efficiency and remove those possible artifacts caused by ambient noise.
Using Animal Models for Gender-Affirming Hormone Therapy
Authors: Aghi Krisha , Goetz Teddy G , Pfau Daniel R , Sun Simón(e) D , Guthman Eartha Mae , Roepke Troy A 
Published: November 2023

Abstract
We have recently proposed experimental design guidelines and areas of study for preclinical rodent models of gender-affirming hormone therapy in neuroscience. These guidelines also apply to any field subject to the influences of gonadal steroid hormones, including metabolism and growth, cancer, and physiology. This perspective briefly describes our suggestions for these fields. Studying the effects of exogenous steroid hormones will have translational benefits for the community. We also discuss the need for equitable practices for cisgender scientists who wish to implement these guidelines and engage with the community. It is necessary that community-informed practices are implemented in preclinical research to maximize the benefit to transgender, nonbinary, and/or gender diverse (TNG) healthcare, which is currently in jeopardy in the United States, Europe, and across the globe.
Aberrant centrosome biogenesis disrupts nephron and collecting duct progenitor growth and fate resulting in fibrocystic kidney disease
Authors: Cheng Tao , Agwu Chidera , Shim Kyuhwan , Wang Baolin , Jain Sanjay , Mahjoub Moe R. 
Published: November 2023

ABSTRACT
Mutations that disrupt centrosome biogenesis or function cause congenital kidney developmental defects and fibrocystic pathologies. Yet how centrosome dysfunction results in the kidney disease phenotypes remains unknown. Here, we examined the consequences of conditional knockout of the ciliopathy gene Cep120, essential for centrosome duplication, in the nephron and collecting duct progenitor niches of the mouse embryonic kidney. Cep120 loss led to reduced abundance of both cap mesenchyme and ureteric bud populations, due to a combination of delayed mitosis, increased apoptosis and premature differentiation of progenitor cells. These defects resulted in dysplastic kidneys at birth, which rapidly formed cysts, displayed increased interstitial fibrosis and decline in kidney function. RNA sequencing of embryonic and postnatal kidneys from Cep120-null mice identified changes in the pathways essential for development, fibrosis and cystogenesis. Our study defines the cellular and developmental defects caused by centrosome dysfunction during kidney morphogenesis and identifies new therapeutic targets for patients with renal centrosomopathies.
Detection of Mycoplasma pneumoniae in hospitalized children with pneumonia in Laos
Authors: Vilivong Keoudomphone , Mayxay Mayfong , Dance David A.B. , De Lamballerie Xavier , Newton Paul N. , Dubot-Pérès Audrey 
Published: November 2023

Mycoplasma pneumoniae has been described worldwide as an important cause of community-acquired pneumonia. From December 2013 to December 2014, 461 children admitted to Mahosot Hospital, Vientiane, Laos, with acute respiratory infection were investigated for upper respiratory microorganisms using probe-based real-time polymerase chain reaction (PCR) (FTD33). M. pneumoniae was detected by FTD33 in the upper respiratory tract of three patients, two girls and one boy, 5.7 and 3.9 years old and 13.6 years old, respectively. They presented with clinical features compatible with M. pneumoniae infection. The two girls were also positive for other potential pathogens. The boy had abnormal pulmonary auscultation, and one of the girls had significant anaemia. These results suggest that enhancement of diagnostic systems for M. pneumoniae detection and analysis of its antibiotic resistance profile is needed to raise awareness and improve understanding of the epidemiology of M. pneumoniae infection in Laos, enable targeted therapy, and inform treatment guidelines.
Uneven Distribution Possibilities of Creative Capital Development in Rural Aareas (Case Study of the Podkarpackie Communes, Poland)
Authors: Szara Katarzyna 
Published: November 2023

Abstract
This paper presents the results of the research, which is an attempt to modify the assumptions of R. Florida’s theory regarding the creative class. The measurement is based on indices that are the basis for the measurement of three categories: talent, technology, tolerance is not always possible due to the lack of data.
The purpose of the study was to identify factors determining activation of creative capital in the areas of communes (local level). The objective results from the need to determine whether or not such conditions are present at the local level.
Using the available literature, a questionnaire was prepared. Its results obtained from a survey among the Podkarpackie residents, were presented in the paper. It was found, as in the case of the results of the work of other authors, that in municipal communes there were better conditions for the development of creative capital.
The Monographic Sociology of Dimitrie Gusti
Authors: Rostás Zoltán 
Published: November 2023

Abstract
This paper briefly presents the method of sociological monography conducted by the Romanian professor Dimitrie Gusti – from its emergence, through its theoretical foundation and application in field research, until its prohibition. The paper explores, step by step, the development of the specific monograph methodology, followed by its introduction in university studies and in the practice of social intervention.
The Bucharest Sociological School that was formed around the monographic field research in the 1930s later began to diversify, but its extinction was due to World War II and to the establishment of the communist regime.
The Legacy of the Monographic Method in Lithuania
Authors: Žvinklienė Alina , Kublickienė Lilija 
Published: November 2023

Abstract
This article attempted to overview the use of the monographic method in sociological research of Lithuania. Historically, the monographic method stimulated the development of rural sociology in Eastern European countries. The fulfilment of the aim is inevitably related to a question about institutionalisation and the development of sociology and such a sub-discipline as rural sociology in Lithuania.
The outcomes of the inquiry allow one to argue that the monographic method is in oblivion rather than in active use, belonging to the history of sociological research in Lithuania. However, the monographic method, often unnamed, is widely applied to contemporary local history research.
The geopolitical reasons had a significant impact on retardation in the institutionalisation and development of national sociology. The politics of national identity management, including those of science and education, can be among the important reasons for the absence of institutionalised rural sociology in Lithuania. However, a national social demographical context determining the permanent public and political need “to solve a peasant question” created the bulk of applied research in the Lithuanian countryside that can be considered as adequate data in the frame of rural sociology.
Are Peasant Households Feasible in Terms of Policy? The Debate on the Future of Semi-Subsistence Households in Ukraine
Authors: Koblianska Inna , Pasko Oleh , Hordiyenko Mykola , Yarova Inessa 
Published: November 2023

Abstract
The paper provides an analysis of semi-subsistence farming in Ukraine during the period 2008–2018, with a special focus on policy towards peasant households, and its feasibility.
Ukraine currently has several strategic documents that set the vectors for regulating the development of the industry. The current policy on the strategic development of agriculture, rural areas, and support for farming is found to be chaotic and inconsistent.
The paper confirms the thesis regarding the low economic efficiency of natural farming, and given the specific weight of households in the production of certain types of food, emphasises that public costs for ensuring the country's food security are thus fairly high. The overall identified trends in the Ukrainian countryside are a) the reduction of land size, naturalisation of economic activity and reduction of market activity (farms, as a rule, keep cattle, poultry and bees, although the safety and quality of livestock products produced in such farms is rather dubious); and b) the enlargement of individual peasant households and their focus on commodity production of agricultural products (mainly crops), with the simultaneous distortion of reported production volumes and, accordingly, tax evasion.
Thus, private peasant households (PPHs) appear as economic structures with a special status: on the one hand, they can be considered as full participants in the market of agri-food products (in terms of sales and production), but on the other hand they are not recognised as entrepreneurial structures. This has negative consequences for the local economy as a whole. PPHs are a legalised form of informal employment, an informal entrepreneurial activity. PPHs are, in our opinion, enjoying preferential status in comparison with that of farmers. Furthermore, existing measures (often patchy and haphazard) of political regulation only deepen the problematic functioning of semi-subsistence farms; and taking into account the peculiarities of tax regulation and the obligatory participation of household members in the pension system, in our opinion, they only intensify the crisis in the rural economy and related social problems.
We find that PPHs in their present form (we stress the last four words) are manifestly untenable, and policy-wise are not feasible for Ukraine. The long-term strategy of reforming this crucial part of Ukraine's agriculture should not include new innovations, but be wisely tailored to Ukraine's conditions within the EU. PPHs ought to be accommodated within and be part and parcel of the tax system, and then be an element of future balanced and sustainable rural development. To achieve the latter aim, the recalibration of tax and legal regulations, underpinned by solid strategic policy, is desperately needed.
Gentrified countryside and non-gentrified countryside: Spatial dimension of the rural gentrification process
Authors: Zwęglińska-Gałecka Dominika 
Published: November 2023

AbstractThe subject of the paper is the process of rural gentrification in Poland. In Poland, this process has a special character. It began later than in the West and intensified in the last decade of the twentieth century. It resulted from two parallel processes endogenous and exogenous to the countryside. The rural middle class grew due to an increase in the level of education of the rural population (resulting from the “educational boom” after 1989) since a higher level of education entitles one to occupy a higher position in the social and professional structure. It was accompanied by the settlement of the urban middle class in rural areas. The paper identifies (based on literature and earlier own research) the features of rural gentrification in Poland. Based on them, the level of gentrification of rural communities was indicated, and in turn, the spatial extent of the rural gentrification process in Poland was defined.
The rural linguistic landscape of Banat
Authors: Sorescu-Marinković Annemarie , Salamurović Aleksandra 
Published: November 2023

Abstract
While the main body of linguistic landscape (LL) research still focuses on urban areas, more recent works have broadened the scope and conceptualisation of LL to include rural spaces. However, these works almost exclusively examine the Global North or the Global South. Suspended somewhere between the Global North and the Global South, the so-called Global East, to which Southeast Europe belongs, is for the most part excluded not just from notions of globality, but also from LL studies. The aim of this paper is to redirect the focus of LL research to a rural area in the Global East, namely, the village Ečka in the Serbian Banat, a region with a specific and lengthy history of multilingualism. We hold that the typologies used for the study of urban LL cannot yield relevant results if applied to rural LL. Our study is based on data collected in 2020 and 2021 during six field trips to Ečka which resulted in more than 300 photographs containing inscriptions in different languages and scripts. Furthermore, we conducted participant observation by recording interviews and collecting walking narratives from locals in Serbian or Romanian. Our study confirmed that there is a gap between the official multiculturalism and multilingualism policy as declared and implemented by top-down agents and the gradual transition to monolingualism and monoscriptalism at the bottom-up level. Therefore, instead of the classical top-down and bottom-up distinction, we propose seeing the village space from a two-fold perspective: the synchronic LL, which mirrors the current use of languages, language prestige and language policies, and the memorial LL, which is a chronicle of the multilingualism of past generations and welcomes a diachronic perspective of LL.
Conceptual and Theoretical Foundations of Research on Social and Cultural Processes in the Environment of the Titular Nation of the Ukrainian SSR during the 1960s and 1970s
Authors: Kindrachuk Nadia 
Published: November 2023

The article considers the сonceptual and theoretical foundations of research on social and cultural processes in the environment of the titular nation of the Ukrainian SSR during the 1960s and 1970s. It is characterized by the semantic content of concepts of “titular nation” and “indigenous people” in the Ukrainian SSR, identified primarily with Ukrainians, who were united by a single language, faith, spirituality, national traditions, customs, culture, ethnic origin and ancient residence on the territory of Ukraine, the official name of which was determined by their nationality. The conceptual components of the research are interpretation of the following concepts of: “Ukrainian ethnos”, “Ukrainian ethnic territory” or “Ukrainian ethnic land”, “national majority”, “national minority”, “nation-state”, “nonconformism”, “counterculture”, “sixties”, “dissidence”, “Ukrainian diaspora”, etc.
Research of the conceptual and theoretical foundations of the outlined topic makes it possible to resolve controversial issues which have not been adequately covered in historical science, also makes it possible to specify the process of national self-expression of Ukrainians through cultural space, and allows to get new assessments, judgments and conclusions.