bluuebunny/crossref_metadata_2025_split huggingface dataset:
Estratégias Pedagógicas para a Construção da Competência Socioafetiva Empatia na Educação a Distância
Authors: Oliveira Ariane Wisnieski de , Schorn Gabriella , Amaral Karen Priscilla Severo , Longhi Magalí Teresinha , Behar Patricia Alejandra 
Published: November 2023

O artigo tem como objetivo verificar a aplicação de estratégias pedagógicas que estejam alinhadas à construção da Competência Socioafetiva Empatia no Ensino Superior de cursos de Educação a Distância. O levantamento teórico foi realizado por meio de publicações sobre o tema e os dados foram coletados por meio de questionário direcionado a professores com perguntas abertas e fechadas, sendo analisado ​​por meio da escala likert de concordância. Os resultados foram avaliados seguindo as premissas da análise de conteúdo. Após o recebimento e análise das respostas, constatou-se que há necessidade de avançar em pesquisas que possibilitem ao professor maior conhecimento sobre a construção da Competência Socioafetiva Empatia na Educação a Distância. No entanto, os resultados apontaram que o professor apresenta interesse e preocupação em relação ao assunto, pois está atento às necessidades dos seus alunos, tanto coletiva quanto individualmente. Observa-se também que as estratégias pedagógicas, mesmo não sendo diretamente direcionadas à Competência Socioafetiva Empatia, em muitos casos, cumprem essa função, estabelecendo condições para que os alunos construam conhecimentos, habilidades e atitudes neste sentido.

Palavras-chave: Educação. Competência. Empatia.
The EPOR/CD131 heteroreceptoragonist has an endothelioprotective effect against the background of pulmonary hypertension caused by monocrotalin
Authors: Korokina Lilia V. 
Published: November 2023

Introduction: The abnormal increase in pulmonary pressure observed in pulmonary arterial hypertension (PAH) is a consequence of increased pulmonary vascular resistance due to progressive loss and obliteration of pulmonary arteries. The initial trigger is a combination of factors that lead to endothelial damage and impaired vascular regeneration. Aim: research the possibilities of pharmacological correction of pulmonary arterial hypertension induced by monocrotalin using the EPOR/CD131 heteroreceptor agonist with the laboratory code EP-11-3.
Materials and Methods: The study of pharmacological activity on a model of monocrotaline induced PAH was carried out on male Sprague-Dawley rats weighing 180-220 grams. Monocrotaline (MCT) pulmonary hypertension was simulated in 30 animals using subcutaneous injection of MCT at a dose of 60 mg/kg. Seven days after the injection of MCT, the administration of the studied compounds began. The erythropoietin derivative with the laboratory code EP-11-3 and pHBSP administered subcutaneously at a dose of 25 mcg/kg once every 3 days for 21 days.
Results: On the model of monocrotalin-induced PAH, it was shown that the erythropoietin derivative with the laboratory code EP-11-3 has a pronounced endothelioprotective effect, reducing the coefficient of endothelial dysfunction, statistically significantly increasing the expression of VEGF-R2 mRNA and reducing the expression of SDF-1 mRNA, reducing the concentrations of CT-1 and PNP, and reducing the signs of remodeling of the heart and pulmonary vessels.
Conclusion: Erythropoietin derivative with laboratory code EP-11-3 has an endothelioprotective effect and reduces the manifestations of vascular remodeling in pulmonary hypertension caused by monocrotalin.
THE RESULTS OF THE INTRODUCTION OF DISTANCE LEARNING TECHNOLOGIES ON THE EXAMPLE OF THE INDICATORS OF THE STATE FINAL CERTIFICATION OF STUDENTS OF THE FACULTY OF DENTISTRY OF USMU FOR 2019, 2020 AND 2022
Authors: Zholudev Sergey , Kozmenko Anastasia , Dregalkina Anna , Gainetdinov Maksim 
Published: November 2023

The educational process has undergone significant changes throughout the history of mankind. Over the past few years, in connection with the COVID-19 pandemic, a model of distance and mixed learning format has been integrated into the educational activities of universities, implying the use of distance educational forms. To assess the effectiveness of this model of education, it is necessary to analyze the final academic performance of a graduate student, his readiness for practical activity, possession of a certain set of skills and abilities in comparison with the classical model of education. In the course of this study, it was found that the academic performance of students of the Faculty of Dentistry according to the results of the state final certification, when comparing the classical model of education with distance learning, remains at a high level: there are no unsatisfactory results in all three stages of certification, high rates of obtaining positive grades by certified students remain, which indicates the correct choice of the trajectory of the educational process.
Subject. Results of the state final certification at the Ural State Medical University in 2019, 2020 and 2022.
Objectives. Comparative analysis of the results of the training of graduates of the Faculty of Dentistry in various training conditions.
Methodology. The data of the results of the State final certification of students of the Faculty of Dentistry for the period in 2019, 2020 and 2022 were studied. The selected time period includes the period of preparation of students in the conditions of a pandemic using various learning technologies.
Results. In the analyzed period, the indicators of the state final certification were consistently high and equivalent relative to the total number of graduates, regardless of the form of study. When comparing all formats of the educational process, according to the results of the certification, there were no unsatisfactory results, which indicates the effectiveness of both the classical form of full-time education and the mixed form of the educational process in the distance format.
Conclusion. Given the similarity of the results of the final certification, we can conclude about the effectiveness of forms of distance education along with classical ones.
CLINICAL CASE OF CRANIOCLAVICAL DYSOSTOSIS SYNDROME: CLINICAL AND X-RAY MANIFESTATIONS
Authors: Chuykin Sergey , Davletshin Nail' , Chuykin Oleg , Makusheva Natal'ya , Kuchuk Kristina , Bilak Anna 
Published: November 2023

Objectives. Clinical case in the practice of an oral and maxillofacial surgeon: a child with cranioclavicular dysostosis. This cider was first described in 1898 by P. Marie and P. Sainton. H. Scheuthauer described the pathological manifestations of skeletal anomalies in more detail. Steithauer–Marie–Sainton syndrome, or cranioclavicular dysostosis, involves aplasia or hypoplasia of the clavicles, delayed dentition, supernumerary teeth, and other skeletal abnormalities. In this syndrome, skeletal abnormalities include clavicular aplasia, or hypoplasia, bell-shaped chest, enlarged cranial vault with a convex frontal bone, open fontanelle, brachydactyly, pelvic hypoplasia, short stature, severe abnormal development of teeth with changes in occlusion, that is, this is a fairly severe hereditary pathology . Retention and dystopia of permanent teeth are associated with the presence of one or more supernumerary teeth on the upper and lower jaws.
Purpose. Conducting an anthropometric, dental, and x-ray examination of a child with cranioclavicular dysostosis.
Methodology. The article presents photographs of the child, pediatric and dental examination data, plain radiography of the chest and collarbones, orthopantomography of the upper and lower jaw, and a treatment plan for cranioclavicular dysostosis. Currently, due to a problem with teething, she consulted a dentist; after an examination, the child was referred to a maxillofacial surgeon.
Conclusions. Cranioclavical dysostosis syndrome is a complex congenital pathology, the complex rehabilitation of which should involve not only doctors of all dental specialties, but also maxillofacial surgeons, orthopedists, pediatricians, neurologists, speech therapists, and medical psychologists.
Pengaruh Gamifikasi Pekerjaan dan Kepuasan Kerja terhadap Enjoyment Karyawan Perusahaan Startup di Yogyakarta
Authors: DINDA SUKMANINGRUM.,ST.,MM  , Dodi Setiawan Riatmaja  
Published: November 2023

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh gamifikasi dan kepuasan kerja terhadap employee enjoyment dengan motivasi sebagai mediator. Penelitian ini dilakukan dengan mengambil karyawan startup di Yogyakarta secara acak sebanyak 73 karyawan. Teknik perhitungan yang digunakan dalam penelitian ini adalah model Analisis Regresi Linier Berganda dan analisis jalur. Berdasarkan hasil analisis menunjukkan bahwa terdapat pengaruh yang signifikan antara gamifikasi terhadap employee enjoyment dan kepuasan kerja terhadap employee enjoyment. Gamifikasi juga memiliki pengaruh tidak langsung terhadap enjoyment dengan motivasi sebagai mediator dan kepuasan kerja memiliki pengaruh tidak langsung terhadap enjoyment karyawan dengan motivasi sebagai mediator.
Kata kunci: Gamifikasi, kepuasan kerja, kesenangan, motivasi

ABSTRACT
The purpose of this study was to determine the effect of gamification and job satisfaction on employee enjoyment with motivation as a mediator. This research was conducted by taking startup employees in Yogyakarta randomly as many as 73 employees. The calculation technique used in this study is the Multiple Linear Regression Analysis model and path analysis. Based on the analysis results show that there is a significant influence between gamification on employee enjoyment and job satisfaction on employee enjoyment. Gamification also has an indirect effect on enjoyment with motivation as a mediator and job satisfaction has an indirect effect on employee enjoyment with motivation as a mediator.
Keywords: Gamification, job satisfaction, enjoyment, motivation
REALISASI NILAI-NILAI PANCASILA SEBAGAI STRATEGI PEMBENTUKAN IDENTITAS BANGSA DI KALANGAN MAHASISWA UNIVERSITAS SEBELAS MARET DI ERA BUDAYA GLOBAL
Authors: Abdullah Felci Amelia , Sariyatun Sariyatun , Ediyono Suryo 
Published: November 2023

<em><span>Pancasila as the ideology of the Indonesian nation, was born with a long process and formulation. As a plural country, Indonesia consists of various ethnic groups, religion and cultures. Of course, it is not an easy matter to unite the diversity. So that Pancasila is here to balance all the deffernces that exixt. In a accordance with the values contained in Pancasila. However, the problem is, Pancasila as a national identity is no longer neglectedl. Global cultural factors that entered Indonesia brought many changes to the nation’s generation. For example, the morale of many generations to the nation has deteriorated. The spirit of nationalism in the easy generation is no longer the same as the spirit of youth nationalism in the era of independence. So the values contained in Pancasila need to be upheld. This writing aims to educate the realization of Pancasila values as a strategy for forming national identity among students. Where students themselves, have a big enough contribution to strengthen national identity. Trough educational activities among the academic community it becomes a suitable forum for instilling and realizing Pancasila values to the nation’s generation.</span></em>
FUNCTIONAL RELATIONSHIP OF THE PROCESSING CONDITIONS WITH PARAMETERS OF THE CONDITION OF THE SURFACES OF RAIL TEETH
Authors: Yurchyshyn Oksana , Piven Larisa , Skidan Natalia , Permiakov Yehor , Mironenko Oleh , Yurieva Mariia 
Published: November 2023

A significant number of mechanical methods, machines, tools and materials for processing toothed rails determines wide possibilities in ensuring the formation of the parameters of the surface layer of the latter and determines their operational properties. Therefore, the issue of ensuring the operational properties of toothed rails depending on the parameters of the condition of the surface layer of the rails is relevant. In order to successfully solve this problem, the theoretical aspects of the relationship between the parameters of the state of the surface layer of the rails and the processes of their processing are considered.
In contrast to well-known studies, which provided for the identification of general aspects of the connection of individual parameters of the surface layer of rails with the conditions of their processing, the authors proposed the feasibility of considering the dependence of the system of parameters of the surface layer, which determine the operational properties of toothed rails, with the conditions of their processing. This relationship is expressed in mathematical dependencies, which are the basis for the development of algorithms and programs. As a result, the solution of one of the main tasks of calculating the optimal processing processes, taking into account the provision of the necessary parameters of the state of the surface layer of toothed rails, based on their operational properties, is automated. In support of this direction, the fundamental scientific principles of the theory of geometric three-dimensional modeling of the interconnected processes of allowance removal and forming during cutting have been developed.
Using the benefit-harm trade-off method to determine the smallest worthwhile effect of intensive motor training on strength for people with spinal cord injury.
Authors: Harvey Lisa , Tranter Keira , Glinsky Joanne , Ben Marsha , Patterson Helen , Blecher Lynn , Chu Jackie 
Published: November 2023

Abstract
Study design: Interviews using the benefit-harm trade-off method and an online survey.
Objectives: To determine the smallest worthwhile effect (SWE) of motor training on strength for people with spinal cord injury (SCI).
Setting: SCI units, Australia
Methods: Forty people with recent SCI who had participated in motor training as part of their rehabilitation program (patient participants) and 37 physiotherapists (physiotherapist participants) working in SCI were recruited. The patient participants underwent an iterative process using the benefit-harm trade-off method to determine the SWE of motor training on strength. The physiotherapist participants were given an online survey to determine the SWE for five different scenarios. Both groups considered the SWE of a physiotherapy intervention involving an additional 12 hours of motor training for 10 weeks on top of usual care. They were required to estimate the smallest improvement in strength (points on the Total Motor Score within the International Standards for Neurological Classification of SCI) to justify the effort and associated costs, risks or inconveniences of the motor training.
Results: The median (interquartile range) smallest improvement in strength that patient and physiotherapist participants deemed worth the effort and associated costs, risks or inconveniences of the motor training was 3 (1 to 5) points, and 9 (7 to 13) points, respectively.
Conclusions: People with recent SCI are willing to devote 12 hours a week for 10 weeks of motor training in addition to their usual care to gain small changes in strength. Physiotherapists wanted to see greater improvements to justify the intervention.
Reinforcement Learning for Efficient Bus Priority Systems: Balancing Transit Efficiency and Traffic Impact
Authors: Kampitakis Emmanouil , Katzilieris Konstantinos , Vlahogianni Eleni I. 
Published: November 2023

Abstract

In this research, two innovative and adaptive bus prioritization strategies are presented; Adaptive Bus Lanes with Intermittent Priority (A-BLIP) and Bus Lane Density Control (BLDC). Both strategies harness the potential of connected vehicles and Vehicle-to-Everything (V2X) communication and aim to enhance the reliability and efficiency of bus operations. Trained through reinforcement learning, they consider buses as intelligent local regulators of traffic, making informed decisions to strike a balance between optimizing bus operations and ensuring the smooth flow of vehicular traffic, based on the specific priorities set by the urban transportation authorities. An intelligent A-BLIP bus agent is trained to dynamically adjust the length of “exclusion zones” based on real-time information on bus delays and traffic conditions, while a BLDC agent controls the density of vehicles within bus lane sections. The strategies are evaluated in a multi-agent setting under various traffic and public transport demand scenarios and compared against the dedicated bus lanes strategy and mixed traffic conditions. The results demonstrate that both A-BLIP and BLDC closely approximate mixed traffic conditions' (i.e., when no restrictions are applied) impact on vehicular traffic while significantly improving bus operations. The strategies' adaptability and performance in extreme scenarios make them promising solutions for enhancing urban transportation management and promoting more sustainable mobility choices.
Identification of epigenetic silencing of the SFRP2 gene in Colorectal Cancer as a Clinical Biomarker and Molecular significance
Authors: MACIAS-GONZALEZ MANUEL , BOUGHANEM HATIM , PILO JESUS , GARCIA-FLORES LIBIA ALEJANDRA , arranz isabel , RAMOS-FERNANDEZ MARIA , ORTEGA-CASTAN MARIA , CRUJEIRAS ANA BELEN , SANDOVAL JUAN 
Published: November 2023

Abstract
This study hypothesized that investigating the promoter methylation of SFRP2 gene in various biological samples from patients with CRC could offer novel biomarker utility. Methods: The study examined SFRP2 gene expression and methylation in both healthy individuals and CRC patients. We assessed the comprehensive biomarker description value of SFRP2 in CRC, validated SFRP2 expression and methylation in diverse biological tissues, and evaluated its potential role as a biomarker in CRC. Furthermore, we investigated the effects of rhSFRP2 on cell proliferation, migration, and the expression of key genes associated with carcinogenesis and the Wnt pathway. RESULTS SFRP2 promoter methylation in whole blood significantly predicted cancer stage, lymph node invasion, and cancer recurrence in CRC patients (p<0.05). The global SFRP2 gene was found to be hypomethylated in CRC (p<0.001), and these results were validated in the TCGA-COAD and TCGA-READ cohorts. Promoter SFRP2 DNA methylation was responsive to chemotherapy, with treated CRC patients exhibiting lower SFRP2 methylation compared to untreated CRC patients (p<0.001). Low promoter SFRP2 methylation in untreated patients was linked to poor overall survival (p<0.05). In a functional analysis of a cell system, rhSFRP2 treatment in HCT116 cells restrained cell proliferation and migration, and led to the downregulation of the AXIN2 gene, which is implicated in the Wnt signaling pathway. Conclusion: These findings establish SFRP2 as a prospective gene in CRC, with potential utility in clinical settings, and provide molecular insights into its involvement in colorectal carcinogenesis, offering novel therapeutic approaches for CRC.
Precision Diagnosis of Chronic Kidney Disease: Genetics Makes the Difference
Authors: Garcia Maria del Mar Del Aguila , Andujar Antonio M Poyatos , Garcia Ana I Morales , Diaz Maria Luz Bellido , Pino Maria del Carmen Velazquez de Castro del , Soto Juan Antonio Bravo , Rosa Rafael J Esteban de la 
Published: November 2023

Abstract
A significant number of renal patients suffer from some hereditary nephropathy and are unaware of it. The information we have, derived from the clinical history and imaging tests, may be adequate to diagnose cases such as autosomal dominant polycystic kidney disease (ADPKD), but insufficient to diagnose other pathologies and at this point, molecular study provides support. We analyse the agreement between clinical and genetic diagnosis in 383 patients with renal disease to evaluate the usefulness of molecular analysis as a tool to reach an accurate diagnosis. Genetic testing was performed by massive sequencing on probands with chronic renal disease and suspected genetic cause from 2018 to 2022. Clinical-genetic diagnostic agreement in patients with ADPKD was 45%, however, in other less prevalent inherited pathologies, such as Alport syndrome drops to 26%, perhaps due to their diverse phenotypic spectrum, where autosomal dominant inheritance pattern is the most frequent. Additionally, we report the history of a family with hereditary chronic kidney disease where different clinical were proposed. The molecular study identified a new variant in COLA4A gene, present in heterozygosity in all affected individuals and the diagnosis of AS was pointed out. Genetics offers an approach to precision diagnosis of renal disease. Its availability helps clinician to better classify individuals and families, makes it easier for patients to participate in specific clinical trials and to choose reproductive options that prevent the transmission of the disease to offspring, which will contribute to reducing the frequency of hereditary nephropathy in the future.
The gender influence on popliteal angle and dorsiflexion in junior high school students
Authors: Pietrzak Krzysztof , Bania Artur , Nowocień Krzysztof , Kraszewski Bartosz , Wiernicka Marzena 
Published: November 2023

Abstract
Background:
The aim of the study was to assess factors affecting the popliteal angle and foot dorsiflexion, in particular gender. The subjects were 142 students from the 2nd and 3rd year of Poznań junior high schools.
Methods:
The participants included 57 girls and 87 boys. Three raters examined each subject: a specialist in orthopaedics, a resident doctor and a physical therapy student.
Foot dorsal flexion was tested in a supine position with lower limbs extended. Next, dorsal flexion was evaluated with the knee and hip in 90 degrees of flexion. Finally, a passive knee extension (PKE) test was carried out. The significance of the PKE test is that the lower the angle the more flexible the hamstrings. This is because the PKE measurement is the distance to the right angle, that is a full knee extension with the hip flexed.
Results:
The non-parametric test (Mann-Whitney) and the Student’s t-test showed a correlation between the female gender and the popliteal angle (p <.05000). The correlation was negative, which means that the hamstrings are more flexible in girls. No correlation was found between gender and passive foot dorsiflexion and dorsiflexion with a flexed hip and knee.
Conclusions:
Girls between 13 and 15 years old have a significantly larger hamstring flexibility, which is confirmed by the tests of the popliteal angle. No differences were found in dorsiflexion between girls and boys who have not been trained using a training model.
NiCo2S4/rGO composite electrode material derived from CO-based MOFs for high-efficiency hybrid supercapacitors
Authors: ZHAO Ji-wei , WEI Zhi-qiang , WANG Can , ZHOU Mei-pan , Lu Cheng-gong 
Published: November 2023

Abstract
The Co-based organic skeleton was combined with graphene oxide (GO) as a precursor, Ni2+ hydrolysis etching was introduced, and finally, NiCo-LDH was obtained. The final composite electrode material NiCo2S4/rGO was obtained by high-temperature vulcanization. The introduction of MOFs and rGO significantly increased the specific surface area of the material and made it have excellent electrochemical properties. The specific capacitance of the composite NiCo2S4/20rGO reaches an astonishing 2452.65 F g− 1 when the current density is 1 A g− 1. In addition, at a large current of 10 A g− 1, the specific capacitance of the material can also reach 1250 F g− 1, and after a long cycle of 5000 cycles at such a current density, the capacity remains at the original 73.2%. With NiCo2S4/20rGO electrode material as the positive electrode and activated carbon as the negative electrode, the hybrid supercapacitor is assembled. At an energy density of 56.9 Wh kg− 1, its power density reaches an excellent 799 W kg− 1, and it still has a capacity retention rate of 74% at a current density of 10 A g− 1. The excellent properties of composites demonstrated in this work open up new possibilities for high-quality energy storage devices.