bluuebunny/crossref_metadata_2025_split huggingface dataset:
Внедрение технологий сопровождаемого проживания инвалидов: ресурсы, барьеры и перспективы (на примере Дагестана)
Authors: Мусаева С.Дж. , Абдулаева И.М. 
Published: February 2025

в статье рассматриваются перспективы внедрения технологии сопровождаемого проживания инвалидов как инновационной формы стационарозамещающего социального обслуживания в Республике Дагестан. Исследование основано на анализе нормативно-правовой базы, практик других регионов России и мнений экспертов из социальных учреждений Дагестана. Выявлены ресурсы и барьеры, влияющие на реализацию данной технологии, такие как недостаток финансирования, нехватка квалифицированных специалистов и помещений, а также низкая осведомленность целевой аудитории. Предложены рекомендации по преодолению препятствий, включая обучение кадров, развитие социального партнёрства и популяризацию технологии среди населения. Результаты исследования подчеркивают значимость внедрения сопровождаемого проживания для повышения уровня жизни людей с инвалидностью и их интеграции в общество.
the article discusses the prospects for the introduction of assisted living technology for the disabled as an innovative form of hospital-substituting social services in the Republic of Dagestan. The study is based on an analysis of the regulatory framework, practices of other regions of Russia and the opinions of experts from social institutions in Dagestan. The resources and barriers affecting the implementation of this technology have been identified, such as lack of funding, lack of qualified specialists and premises, as well as low awareness of the target audience. Recommendations for overcoming obstacles are proposed, including staff training, the development of social partnership and the popularization of technology among the population. The results of the study emphasize the importance of introducing assisted living to improve the standard of living of people with disabilities and their integration into society.
Цифровая образовательная инфраструктура университета как технологическая экосистема будущего
Authors: Павлюк Е.С. , Павлюк Л.В. 
Published: February 2025

анализ содержания экосистемы настроил авторов на исследование ее влияния на состояние рынка образовательных услуг высшей школы в случае поэтапного формирования консолидированного цифрового пространства с многообразием софтов, свойственных ранее, исключительно коммерческой среде, а именно, банкам, цифровым компаниям-гигантам, мультимедиа холдингам, сфере консалтинга и аудита. Как показывает практика, сфера образования давно выступает в качестве стабильного приемника процессов и технологий, изначально разрабатываемых для бизнес-сообщества. Анализ экосистемы, как понятия из биологии, адаптированного под свойства и процессы, происходящие в условиях цифровой экономики, свидетельствуют о том, что экосистема соответствует представлениям экономического и образовательного сообщества о том, что можно назвать единым пространством сегодня в эпоху Промышленной революции 4.0. Интерактивность данной среды, как одно из ее ключевых свойств, позволяет верить в то, что она станет стратегически верным шагом на пути оптимизации цифровой трансформации процессов управления в системе высшего образования, так как позволяет объединить образовательный продукт, образовательные технологии, образовательные каналы, бизнес образования в условиях цифровой экономики страны в единое «цифровое облако».
the analysis of the ecosystem content led the authors to investigate its impact on the state of the higher school educational services market in the case of the phased formation of a consolidated digital space with a variety of software previously peculiar exclusively to the commercial environment, namely, banks, digital giant companies, multimedia holdings, consulting and auditing. As practice shows, the field of education has long been acting as a stable receiver of processes and technologies originally developed for the business community. The analysis of the ecosystem, as a concept from biology adapted to the properties and processes occurring in the digital economy, indicates that the ecosystem corresponds to the ideas of the economic and educational community about what can be called a single space today in the era of the Industrial Revolution 4.0. The interactivity of this environment, as one of its key properties, allows us to believe that it will become a strategically correct step towards optimizing the digital transformation of management processes in the higher education system, as it allows us to combine an educational product, educational technologies, educational channels, business education in the digital economy of the country into a single «digital cloud».
Имплементация российского законодательства в сфере противодействия легализации (отмыванию) доходов, полученных преступным путем, и финансированию терроризма в зарубежные филиалы российских банков
Authors: Семеруха С.А. 
Published: February 2025

в настоящее время, ведущие российские банки, находясь под усиленным санкционным давлением, переориентируются на азиатские рынки, чтобы обеспечить своим клиентам возможность осуществления трансграничных платежей, конвертации кредитов, взятых в валюте «недружественных» стран и других задач, возникших в условиях ограничений и рестрикций. Одним из решений вышеуказанных вопросов является открытие зарубежного филиала в «дружественной» юрисдикции. Однако такое решение, вероятно, является наиболее трудоемким из всех возможных, в том числе потому, что требует применения законодательств двух стран по некоторым нормативно-правовым актам. В представленной статье рассматривается необходимость по исполнению законодательства Российской Федерации в сфере противодействия легализации (отмыванию) доходов, полученных преступным путем, и финансированию терроризма, а также изложен взгляд по его имплементации в зарубежный филиал российского банка. По итогу проведения исследования предложены возможные инструменты, с опорой на российское законодательство и международные стандарты в сфере ПОД/ФТ, способствующие более эффективному исполнению российского антиотмывочного законодательства.
nowadays the leading Russian banks, under increased sanctions pressure, are refocusing on Asian markets to ensure that their clients can make cross-border payments, convert loans taken in the currency of “unfriendly” countries and other tasks that have arisen under the restrictions. One solution to the above issues is to open a foreign branch in a “friendly” jurisdiction. However, such a solution is probably the most labour-intensive of all possible solutions, also because it requires application of the legislations of two countries on some regulations. The presented article considers the necessity to implement the legislation of the Russian Federation in the field of anti-money laundering and terrorism financing, as well as outlines a view on its implementation in a foreign branch of a Russian bank. Based on the results of the study, possible instruments, based on Russian legislation and international AML/CFT standards, have been proposed to facilitate more effective implementation of the Russian anti-money laundering legislation.
Description of three new species of genus Vacrothele (Araneae, Mygalomorphae, Macrothelidae) from China with notes on two taxonomic amendments
Authors: Zheng Yu-Lin , Zhao Yu , Yang Zi-Zhong 
Published: February 2025

Three new species of the genus Vacrothele Tang &#38; Yang, 2022 are described in detail from China: Vacrothele fuyuanensis sp. nov., Vacrothele jiangkouensis sp. nov. and Vacrothele baiseensis sp. nov. Two described species of the Macrothele are transferred to the genus, i.e., Vacrothele emei (Lin &#38; Li, 2021) comb. nov. and Vacrothele taiwanensis (Shimojana &#38; Haupt, 1998) comb. nov. A key to species of Vacrothele and a geographic distribution map are given.
Professionalism of Caregivers as a Pivot to Effective Literacy Skills in Pre- School Classes
Authors: Opeyemi Oyewumi Nasimot , Lawal Oluwaseun Temitope , Orisadare Hamdalah Adejoke 
Published: February 2025

This study aims to examine the qualifications of caregivers/teachers as well as the level of professionalism and teaching methods of literacy skills carried out in preschool classes. The study adopted descriptive survey research design. The population comprised all caregivers in private schools in Iwo Local Government, Area of Osun state, Nigeria. The sample consist 3 teachers that were purposively selected from 20 private schools that were randomly selected using simple random sampling technique to make a total number of 60 caregivers. Self - developed questionnaire was used to collect data for the study. Data collected were analyzed using frequency count, percentage, and standard deviation. The results revealed that low percentage 6.7% of caregivers were ECCE certificated, 43.3% had other education disciplines, 46.7% were registered under Teachers Registration Council of Nigeria (TRCN), 52.2% uses the expected methodology for teaching literacy skills while 67.2% were engaged in various professional development and collaborate in teaching literacy skills. It can be concluded that the professionalism of pre-school caregivers/teachers in term of certification is very low, less than 50% were professionally registered but the methodology applied in teaching literacy skills are appropriate. The study recommended that school owners should make recruitment of ECCE professionals a priority and encourage caregivers to engage more in professional development that will equip them in the field of ECCE.
Application of Bioinformatics Analysis to Identify Important Pathways and Hub Genes in Breast Cancer Affected by HER-2
Authors: Tjipta Arya , Hermansyah Dedy , Suzery Meiny , Cahyono Bambang , Amalina Nur Dina 
Published: February 2025

Human epidermal growth factor receptor 2 (HER-2) is used as a marker for the diagnosis and prognosis of breast cancer. However, the molecular mechanisms involving HER2 in breast cancer require further study. Herein, we used the bioinformatics approaches to identify important pathways and hub genes in breast cancer affected by HER-2. The results showed that HER-2 is highly expressed in ovarian cancer and is closely related to the overall survival and progression-free survival of breast cancer. A total of 3014 downregulated genes and 4121 upregulated genes were identified under Gene Expression Omnibus (GEO) database with the GEO2R tool. Among them, the top 10 hub genes including CCNB1, KIF11, BUB1B, TOP2A, ASPM, MAD2L1, BUB1, RRM2, EGFR, and FN1 demonstrated by connectivity degree in the protein-protein interaction (PPI) network were screened out. In Kaplan–Meier plotter survival analysis, the overexpression of CCNB1, EGFR, MAD2L1, ASPM, and RRM2 were shown to be associated with an unfavourable prognosis in HER-2 positive breast cancer patients. In conclusion, we have identified important signalling pathways involving HER-2 that affect breast cancer. These findings could provide new insights outlining mechanisms involving HER-2 gene expression in breast cancer and provides a rationale for the novel treatment of breast cancer.
Anti-inflammation effect of Apium graveolens Extract against lead-acetate-induced brain injury in rats
Authors: Sulistyo Sona , Sarosa Hadi , Sumarawati Titiek , Putra Agung , Chodidjah Chodidjah , Amalina Nur Dina , Ibrahim Sugeng 
Published: February 2025

Purpose: The current study investigated the protective potential of Apium graveolens extract (APE) against lead-induced brain injury in rats by exploring anti-inflammatory and antiapoptotic mechanism. Methods: Twenty male Wistar rats were randomly allocated into four groups (n=5). The control group was orally administrated with distillate water. The second group received lead acetate 200mg/kg body weight orally for 14 days, the third group were orally administered lead acetate 200 mg lead acetate/kg body weight and vitamin E 50IU/kg body weight for 14 days. The fourth group was administrated with leas acetate like second group and APE 300mg/kg body weight for 14 days. The TNF-a levels and caspase-3 expression was analyses under ELISA and flow cytometry assay, respectively. Results: The phytochemical analysis of APE indicated the presence of alkaloids, flavonoids, tannins, saponins, and steroids. Leads acetate increased the serum levels of TNF-α and caspase-3 expression, as well as altering the brain tissue architecture. Conclusion: In conclusion, the presence of APE inhibited the lead acetate toxicity by inhibition of TNF-α proinflammation protein and caspase-3 proapoptosis protein.
El juego cooperativo como medio didáctico para estimular el desarrollo socio afectivo en niños de Educación Inicial Subnivel II
Authors: Cedeño Garcia Melissa Johana , De la Peña Consuegra Geilert , Macías Navarrete Andrea Lissette 
Published: February 2025

El juego cooperativo es una actividad lúdica aplicada como método de enseñanza-aprendizaje, fortalece las distintas áreas del desarrollo infantil, de esta manera, surgen cuestionamientos en relación al nexo que tiene el juego cooperativo con el desarrollo socio-afectivo en infantes. Esta investigación tiene como objetivo analizar el efecto del juego cooperativo como medio didáctico en el desarrollo socio-afectivo de niños en edad preescolar. Se emplea como metodología para el estudio de tipo descriptiva, de campo y trasversal, esto acompañado de tareas en función de la sistematización de los fundamentos teóricos relacionados al juego cooperativo y el desarrollo socioafectivo, aplicación de técnicas para la recolección de información cuali-cuantitativas como la observación, entrevista y encuesta. Con los resultados alcanzados en el proceso diagnóstico, se logró determinar que el juego cooperativo puede ser usado como recurso educativo para el desarrollo socio-afectivo, dado que a través de la lúdica se da entrenamiento de habilidades sociales, luego de usar la técnica de observación en dos momentos, inicialmente para el diagnóstico y posteriormente para analizar los efectos de la aplicación de actividades recreativas. A partir de esto, se pudo identificar deficiencia en la comunicación y seguimiento de reglas dentro de las relaciones parentales. De esta manera, se concluye que el juego cooperativo aporta al desarrollo socio-afectivo al propiciar las interacciones sociales y fomentar valores, por otro lado, se resalta la relevancia que tienen los padres y docentes en los distintos ámbitos del desarrollo infantil.
The Influence of Perception of Learning Media and Learning Motivation on Social Science Learning Achievement at Private Junior High Schools in South Jakarta City
Authors: Marlina Reni 
Published: February 2025

Study This aiming For analyze and test truth hypothesis about Influence Perception Students on Learning Media and Motivation Study To Performance Study Knowledge Knowledge Social. Hypothesis study includes : 1) There is significant influence​ perception on learning and motivation media Study to performance learning social studies. 2) There are significant influence​ perception on learning media to performance learning social studies. 3) There are significant influence​ motivation Study to performance study social studies. Research This done with survey method. Population is students / i Private Mts in South Jakarta with big sample as many as 70 students , sample scrambled with use random sampling technique with method raffle. Instrument study with questionnaires, tests, and documents. And have tested shown with all mark asymp, sign > 0.05. This is means the data is normally distributed. Data analysis using Analysis of variance (ANOVA) two path / direction. This is proven with acquisition of Sig.
0.00 < 0.05 and F h = 98.93. 2) Yes significant influence​ perception on learning media to performance study social studies for students of private MTs in South Jakarta. This is proven with acquisition of Sig. 0.00 < 0.05 and t h = 3.246. 3) Yes significant influence​ motivation Study in a way together to performance learning social studies for private Mts students in South Jakarta. This is proven with testing hypothesis obtained Sig. 0.00 < 0.05 and t h = 4.070. The results of the study This useful for teachers, administrators institution education For increase quality of learning media and motivation Study student to performance learning social studies at the Mts level Private
Evaluación de reacciones adversas a medicamentos en un servicio de farmacia: cuatro años de experiencia de un programa de farmacovigilancia
Authors: González Furelos Tania , Rodríguez Legazpi Iria , Fraga Bueno Eva , Granero López Monica , Rodríguez Penín Isaura 
Published: February 2025

Introducción: Las reacciones adversas a medicamentos son uno de los principales eventos adversos que pueden derivar en ingresos hospitalarios. El objetivo de este estudio fue analizar los principales medicamentos causantes de reacciones adversas, la gravedad y el grado de notificación de las mismas.
Material y métodos: estudio observacional, retrospectivo y unicéntrico, llevado a cabo en el servicio de farmacia del hospital de Ferrol desde 2019 hasta 2022. Se incluyeron todos aquellos pacientes registrados en una base de datos asistencial. Se registraron variables relacionadas con: reacción adversa, gravedad, medicamento, modo de detección y notificación.
Resultados: Se detectaron 2.237 reacciones adversas (934 graves, 692 moderadas y 611 leves). Los grupos farmacológicos implicados mayoritariamente fueron: antineoplásicos (38,94%), corticoides (14,71%), diuréticos (14,04%) y antibacterianos (10,05%). La mayoría de las reacciones adversas graves fueron causadas por antineoplásicos (37,94%), antitrombóticos (7,07%) y betabloqueantes (5,03%).
Conclusión: Los antineoplásicos y las alteraciones sanguíneas fueron los medicamentos y las reacciones adversas más frecuentemente detectadas, respectivamente. La participación activa del farmacéutico y la integración de la farmacovigilancia en la práctica asistencial diaria contribuyen a la identificación y notificación de un gran número de reacciones adversas.
Perspektif Orang Kristen Tentang Beladiri
Authors: Rudi Kurosawa  , Iskak Sugiyarto  
Published: February 2025

Self-defense is still a matter of debate among Christians, some agree and some disagree. This is because there are no references to Bible verses that directly explain this. Including the lack of studies on self-defense from a Christian perspective. This research wants to find out how Christians view self-defense. In it, are Christians allowed to participate in martial arts, be allowed to become martial arts trainers, and give tithes from their work as martial arts trainers? The research was conducted using qualitative methods, which collected data by interviewing Christians. As a result of the research, the informants were of the opinion that self-defense can be practiced by Christians as long as there is no mystical element. Christians may become martial arts trainers, and may tithe the proceeds of their work as martial arts trainers.
Pengaruh NPM, ROI dan ROE Terhadap Harga Saham pada Perusahaan Sektor Infrastruktur di Bursa Efek Indonesia Tahun 2019-2022
Authors: Zahra Afelia  , Lihan Rini Puspo Wijaya  , Artie Ardhita Rachman  
Published: February 2025

This study aims to examine the impact of NPM, ROI, and ROE on stock prices. The population of this research consists of infrastructure companies listed on the Indonesia Stock Exchange (IDX) during the period of 2019-2022. This study uses secondary data obtained from the financial statements of infrastructure companies listed on the IDX between 2019 and 2022, which were accessed through the website www.idx.co.id. The research population consists of 23 infrastructure companies listed on the IDX during the 2019-2022 period. Purposive sampling was used to select a sample of 81 observations, which were analyzed using multiple linear regression. The results show that NPM has an effect on stock prices, while ROI and ROE do not have an impact on stock prices.
IMPLEMENTASI DAN RESPON PETERNAK TERHADAP INOVASI PEMBIAYAAN PENGGEMUKAN DOMBA QURBAN “MODEL EKOBIS 30-70”
Authors: Kuswaryan Sondi , Firmansyah Cecep , Daud Andre Rivianda , Fitriani Anita 
Published: February 2025

Ternak mempunyai fungsi penting dalam penghidupan masyarakat perdesaan, memberikan rasa aman, sebagai aset usaha dan tabungan, dan berperan penting membantu mengatasi risiko finansial yang tidak direncanakan, namun sebagai sumber nafkah usahaternak masih berperan sebagai sumber pandapatan tambahan. Peternak domba di Kelompok Peternak Jaya Bakti Desa Citali Kecamatan Pamulihan Kabupaten Sumedang mempunyai motivasi kuat untuk mengusahakan ternaknya sebagai bisnis komersial, dengan memanfaatkan peluang pasar hewan qurban. Peternak ternyata tidak dapat merealisasikan rencana tersebut karena terbatasnya pengetahuan dan pembiayaan. Untuk mengatasi keterbatasan peternak, diintroduksikan inovasi pembiayaan Model Ekobis 30-70, yang merupakan pola bagi hasil antara peternak dan pemodal. Ternak yang digunakan menjalankan program sebanyak 14 ekor, dengan nilai investasi Rp 29.850.000, melibatkan 12 orang peternak. Pasca pemeliharaan selama 6 bulan, diperoleh nilai penjualan domba Rp 44.717.500,00. Nilai tambah total yang diperoleh Rp 14.867.500,00. Dari nilai tersebut peternak mendapatkan bagian 70% sebesar Rp 10.406.250,00. Rata-rat nilai tambah yang dihasilkan Rp 743,375,00/ekor dan peternak mendapatkan nilai tambah sebesar Rp 867.270,83/orang. Nilai tambah investor sebesar Rp 4.460.250,00 atau 14,94 % dari total investas. Nilai tersebut lebih besar dari tingkat bunga deposito bank. Dengan demikian tingkat kelayakan investasi pola bagi hasil Model Ekobis 30-70 memenuhi aspek kelayakan. Oleh karena itu, peternak, masyarakat umum dan perangkat desa memberikan respon yang baik terhadap model pembiayaan yang diintroduksikan.
Nutrigenómica en la prevención del cáncer: una revisión sobre la eficacia de compuestos bioactivos
Authors: Romero Meza Jennifer , Cruz Hidalgo Pablo Andrés 
Published: February 2025

El cáncer es una patología que representa una de las principales causas de muerte a nivel mundial y genera un impacto económico sumamente elevado en los sistemas de salud pública. Sin embargo, una considerable parte de los casos de cáncer podrían prevenirse mediante la adopción de hábitos alimentarios adecuados y la ingesta de alimentos ricos en nutrientes y sustancias bioactivas. El objetivo del presente estudio es sintetizar y evaluar los efectos y eficacia de ciertos compuestos bioactivos en la prevención de alteraciones genéticas, mejora del sistema inmune o reducción de la inflamación sistémica que pueden conducir al cáncer. Se llevó a cabo una revisión sistemática siguiendo las directrices PRISMA, en la que se incluyeron estudios de los últimos 5 años encontrados en la base de datos de la Biblioteca Cochrane. Teniendo en cuenta los criterios de inclusión y exclusión, se incluyeron un total de 16 ensayos clínicos aleatorizados. Los cuales develaron y apoyan que la incorporación de compuestos bioactivos presentes en los alimentos, como polifenoles, carotenoides, glucosinolatos, ácidos grasos omega-3, terpenos, fitoesteroles, lignanos y antioxidantes tienen un impacto positivo en la prevención del cáncer al participar en diversos mecanismos moleculares asociados al mismo.