bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regeneration of Rabbit Auricular Cartilage After the Intravenous Stem Cell Injection
Authors: Virych Pavlo , Shuvalova Nadiia , Karas Anton , Karas Galina , Chaika Svitlana , Kucherenko Tetiana , Minina Ganna , Timchenko Marina , Melnykov Oleg , Minin Yurii 
Published: November 2023

Background. The restoration of auricular cartilage is a major problem of otolaryngology. The low regenerative capacity of cartilage requires alternative approaches such as cell and tissue engineering. Stem cells are one of the ways to repair auricular cartilage damages. The aim of the investigation was the regeneration of an artificial defect of the auricular cartilage of rabbits after the intravenous injection of stem cells.Materials and Methods. The study was carried out on rabbits. A narrow strip of auricular cartilage was surgically removed. A previously prepared suspension of homologous mesenchymal stem cells (5 million) in 0.5 ml physiological solution was injected into the vein of the opposite ear. Tissue samples from the site of the injury were collected after 1, 2, and 3 months. Histological examinations of the tissues were carried out after staining with fuchsin-eosin, azure II–eosin, and according to Weigert. In addition, the amount of interleukin-6 (IL-6) and the transforming growth factor β1 (TGF-β1) in the blood serum were determined.Results. The main method of healing is the formation of a connective tissue scar. Yret, an increase of the number of fibroblasts and single islands of the newly formed auricular cartilage was found, which indicates the migration of the injected stem cells to the site of the damage and settling there. The intravenous injection of stem cells did not affect the secretion of pro-inflammatory IL-6, but significantly increased the amount of TGF-β1.Conclusions. We assume that regenerative processes were stimulated. Nevertheless, they were aimed at quickly restoring the tissue integrity through the typical stages of scar formation. The restoration of cartilage integrity requires additional regulatory factors which will determine the chondrogenic differentiation of stem cells.
Análise do comportamento dos investidores no Multinve$t
Authors: Ribeiro Roberto Portes , Machado Mari Eldionara Rosa 
Published: November 2023

Os jogos de empresas permitem que sejam aplicadas diversas teorias de forma prática e simulada, prendendo a atenção e envolvendo o participante. As finanças comportamentais estudam a maneira como os humanos interpretam e agem frente às informações para decidir sobre investimentos. Nessa ótica, o investidor avalia o risco de um investimento com base em um ponto de referência a partir do qual, mede os ganhos e perdas. O estudo objetiva analisar o comportamento dos acadêmicos da disciplina de jogos de empresas durante a experiência proporcionada pelo Multinve$t, que simula a dinâmica do mercado financeiro. Para tanto, esta pesquisa exploratória de natureza qualitativa utilizou-se de entrevistas semiestruturadas como instrumento de coleta de dados em seis equipes e a análise dos dados se deu por meio de análise de conteúdo. Os resultados indicaram diferenças entre as estratégias e comportamentos das equipes. O Multinve$t mostrou-se importante para a aplicação de teorias financeiras de uma maneira prática e interessante, propiciando aos participantes a aquisição de conhecimentos por meio da simulação. Palavras-chave: Jogos de Empresas. Finanças Comportamentais. Carteiras de Investimento.
Gestão de estoque de restaurantes: um estudo de caso
Authors: Vasconcelos Yumara Lúcia , Yoshitake Mariano , Silva Georgia Fabiana da 
Published: November 2023

O objetivo deste artigo é apresentar quais os controles aplicáveis ao almoxarifado de uma empresa do setor de serviços de alimentação. A empresa estudada tem comocore business o fornecimento de cardápio de massas e vinhos. A pesquisa realizada enquadra-se como qualitativa, de natureza exploratório-descritiva, tendo sido empregado o método de estudo de caso. O estudo apresenta as características, rotinas e procedimentos de controle adotados pela empresa estudada, compondo um estudo de caso (processo de caso único). Os resultados da pesquisa indicam que os controles aplicáveis do restaurante incorporam-se à análise prospectiva e customização dos controles para organizações de pequeno porte. O conceito de controle interno, como um conjunto de processos e rotinas, é parcialmente cumprido pela empresa em estudo. O desenho do sistema de controle na empresa não considera as características da atividade ou negócio bem como as restrições de infra-estrutura. O porte e tamanho do negócio provocam um achatamento no formato do sistema de controle, inviabilizando os procedimentos de cruzamento e conciliação de dados.Palavras-chave: Controle Interno. Empowerment. Informações de Fluxo.
Transporte Público e Acessibilidade: um estudo comparativo da qualidade percebida e esperada por usuários com deficiências em João Pessoa
Authors: Mano Rayane Fernandes , Medeiros Fabiana Gama de , Diniz Ionara Saraí Ferreira Nóbrega , Abreu Nelsio Rodrigues de 
Published: November 2023

A qualidade nos serviços pode ser considerada uma vantagem competitiva e um diferencial estra-tégico para quem dela faz uso. Para proporcionar um serviço de qualidade, as organizações devem considerar a percepção do consumidor, a qual é inﬂuenciada por suas expectativas que, por sua vez, é consequência da comunicação, de suas necessidades pessoais e experiências passadas. Aplicando o método SERVQUAL, objetivou-se analisar e comparar as expectativas e a qualidade percebi-da pelos usuários de transporte público coletivo na cidade de João Pessoa, e especificamente, se os usuários possuem alguma deficiência. A metodologia utiliza o enfoque quantitativo, com uma amostra não probabilística, definida por conveniência, contando com 32 entrevistados. A pesquisa foi realizada na FUNAD de João Pessoa – PB, que proporciona a defesa e garantia dos direitos cons-titucionais da pessoa com deficiência assegurando-lhes o exercício da sua cidadania, inclusive no que se refere aos transportes públicos. A partir dos resultados obtidos, verificou-se que as empresas de transporte público em João Pessoa, apresentam resultados bem abaixo das expectativas dos usu-ários de transporte público com deficiência.
Vacuum-assisted caesarean delivery assessment of maternal & fetal outcome
Authors: Agarwal Manisha , Solanki Sweekrati , Sachau Sumedha 
Published: November 2023

: The baby is delivered via incisions made in the mother's abdomen and uterus during a Caesarean delivery, sometimes known as a C-section. Whether medically necessary or elective, caesarean sections have increased sharply in recent decades all throughout the world, exceeding the WHO-recommended 10-15% rate. Every effort should be taken to give cesarean sections to women in need rather than aiming to achieve a target rate, according to a 2015 WHO statement. Therefore, we must investigate the strategies that can improve CD's maternal and neonatal health condition. This study compares the outcomes for the mother and the newborn in the vacuum-assisted CD and manual CD groups.: A progressive study was conducted at Lucknow's Green cross Hospital between June 2012 and April 2018. 500 pregnant ladies took part in this study as participants. This research was approved by the institutional human ethical committee. 250 caesarean sections were performed as part of this cohort study, each with vacuum assistance utilizing a soft cup vacuum extractor on the fetal scalp and manual removal of the skull as usual with fundal compression as support. Due to the absence of uterine activity and amniotic fluid, all of the patients underwent preplanned caesarean sections. The study's findings showed that manual extraction Caesarean birth is inferior to vacuum-assisted Caesarean delivery. Additionally, it was noted that Vacuum Assisted Caesarean Delivery resulted in less uterine incision extension, estimated blood loss, and maternal discomfort. : There was no difference between Vacuum and Manual Extraction caesarean deliveries in terms of Apgar Score, the requirement for infant resuscitation, or admission to the NICU.
Non-pneumatic anti-shock garment (NASG) and balloon tamponade decrease maternal mortality and morbidity from Obstetrics Haemorrhage: A prospective observational study
Authors: Zarariya Ashish , Chaubey Arya , Harikanth Disha Rama 
Published: November 2023

Obstetric haemorrhage is the leading cause of maternal mortality and morbidity worldwide. A prospective observational study was conducted among 132 women admitted, booked/referred, at tertiary care centre with Obstetric Haemorrhage for 2 years period. Of these 71 patients had received Non-pneumatic antishock garment and / or Uterine Balloon Tamponade (Group 1) and 61 didn’t receive any (Group 2). Both groups were observed for its outcome. The socio-demographic parameters and obstetric characteristics among both groups were comparable. However, there were differences in their outcomes and complications. Surgical interventions were more among group 2 as compared to group 1, B-lynch/Modified B-lynch (8.4% vs. 1.6%), Stepwise devascularisation (2.8% vs. 1.6%) and Obstetric hysterectomy (7.0% vs. 3.2%). There was significantly more blood loss in Group 2 than group 1. Duration of hospital stay was significantly shorter (9.8±2.7 days) in Group 1 as compared to Group 2 (12.7±3.6). The shock index after intervention was significantly smaller (0.7±0.1) in Group 1 in comparison to Group 2 (0.8±0.1) and Group 1 required significantly less number of blood and blood products as compared to group 2. 19.7% required ICU admission in group 1 and 24.6% in Group 2. There was no mortality in group 1 and 3 patients died in group 2. NASG and UBT is both life-saving and cost effective and can become the first defence against Obstetric Haemorrhage.
Nowa polityka reprezentacji różnorodności w amerykańskim przemyśle audiowizualnym jako przykład negocjacji znaczeń
Authors: Morozow Iwona 
Published: November 2023

Przemysł audiowizualny w tzw. erze „post-Weinstein” zaproponował szereg rozwiązań, przekładający się na codzienną sytuację kobiet funkcjonujących w branży. Drugim obserwowalnym elementem jest kształt współczesnych narracji o kobietach, przedstawianych w kategoriach emancypacji, inkluzywności, ale będący też efektem monetyzacji feministycznych trendów. Wszystko to przekłada się na programowe zwiększenie obecności postaci kobiecych w rolach protagonistek, czy też uważniejsze, mniej stereotypowe ich tworzenie i różnorodne reprezentacje w ramach gatunków. Autorka zajmuje się badaniem dyskursów związanych z nową polityką różnorodności w branży audiowizualnej, skupiając się na analizie wybranego przykładu filmu – „Wonder Woman” w reż. Patty Jenkins, często określanego jako początek nowego, subersywnego feminizmu. W analizie wykorzystane zostaną ustalenia brytyjskich studiów kulturowych w zakresie kodowania i dekodowania, a celem będzie określenie stosunku wybranych treści do hegemonicznej narracji, zaś ostatecznie przyjrzenie się i wnioskowanie o dotychczasowych efektach programowych zmian.
Study of biotransformation of new selective carbonic anhydrase II inhibitor 4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide
Authors: Khokhlov A. L. , Yaichkov I. I. , Shetnev A. A. , Ivanovskiy S. A. , Korsakov M. K. , Gasilina O. A. , Volkhin N. N. , Petukhov S. S. 
Published: November 2023

The aim of the study was to determine biotransformation products of a new selective carbonic anhydrase II inhibitor – 4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide.Materials and methods. The study was conducted on 3 Wistar rats and 3 rabbits of the Soviet Chinchilla breed. The suspension of the drug was administered intraperitoneally to rats at a dosage of 20 mg/kg, to rabbits - at a dosage of 1.6 mg/kg. The animal blood samples were collected before the administration and 1, 2, 4, 24 h after. Urine sampling was also performed in the rats before the administration and in the intervals of 0–4, 4–8, 8–24 h after. The identification of metabolites in blood, urine and plasma was carried out using HPLC-MS/MS. Poroshell 120 C 18 column (50×3.0 mm, 2.7 µm) with a Zorbax Eclipse Plus C18 pre-column (12.5×2.1 mm, 5.0 µm) was used for the chromatographic separation. The assumed metabolites were synthesized, their structure was confirmed by the NMR spectroscopy method and a high-resolution mass spectrometry. The obtained substances were compared with the substances identified in biological fluids by retention time, the main MRM-transitions and mass spectra.Results. The N-hydroxymetabolite was revealed in the analyses of plasma, blood and urine samples which had been formed by the addition of an oxygen atom to the drug molecule. Chromatographic peaks of this compound were identified at the MRM-transitions of 255→159, 255→117, 255→89 m/z at the 7.2nd min of the analysis. The N-oxide of 4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide and N-hydroxy-4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide were synthesized; potentially, they could have been obtained during the biotransformation. During the confirmatory HPLC-MS/MS tests based on the coincidence of the retention times, the main MRM transitions and mass spectra, the ratio of the peak areas at the identified metabolite it was established that an N-hydroxy derivative. Chromatographic peaks of the N-oxide detected in the analysis of the model mixtures of the standard substance at the MRM-transitions of 255→175, 255→133, 255→89 m/z at the retention time of 5.43 min, were absent in the animal samples.Conclusion. The studied drug is metabolized to form a single metabolite of N-hydroxy-4-(2-methyl-1,3-oxazole-5-yl)-benzenesulfonamide. This compound was found in freshly collected samples of biological fluids of both animal species. The structure of the metabolite was confirmed by the HPLC-MS/MS-method by comparison with the synthesized standard substance.
Legal Transplant to Decolonization in the Evolution of India’s Corporate Legislation
Authors: Singh Shivansh 
Published: November 2023

In India, most existing legislation resulted from a "legal transplant" that gradually occurred in colonial times. India is a common law country that follows the colonial pattern of law-making. Most of the legislation owes the British East India Company, including regulation of modern business corporations. This paper aimed to examine the history and formation of corporate legislation in India and its deviation from the legislation of the origin country, England. It pointed out the relevance of local conditions in India that led to a different approach to forming corporate law in India. The local conditions in India prevailed over the process of legal transplant. The social, economic, and political factors played a significant role in forming corporate law in India. To such an extent, India deviated from the English company laws and followed the trajectory of different jurisdictions. Using normative legal research, this paper is structured chronologically and progressively to trace the evolution of Indian corporate law. The central premise of the study is that India has strayed from colonial law and current legislation, and its development shows no evidence of strong dependence on English law and little evidence of following in the footsteps of India's colonial past. The economic liberalization and the SEBI Act 1992 simultaneously led to a new approach in corporate law, heavily under the US. The present Indian corporate law and the statutes revolving around it have departed from the transplanted law.
KEYWORDS: Legal Transplant, Corporate Legislation, Company Law.
TEORI SISTEM SEBAGAI FILOSOFI DAN METODOLOGI ANALISIS HUKUM ISLAM YANG BERORIENTASI MAQASHID AL- SYARIâ€™AH (Telaah atas Pemikiran Jasser Auda)
Authors: Rofiah Khusniati 
Published: November 2023

Adanya penyalah gunaan dalam penerapan hukum Islam saat ini, diantaranya; masih bersifat reduksionis dari yang seharusnya holistik, menjadi sangat literal dari yang seharusnya bermoral, menggunakan satu pendekatan dari yang seharusnya multi pendekatan, meyakini dua nilai dari yang seharusnya multi value, dekonstruksi dari yang seharusnya rekonstruksi dan lain sebagainya, telah mendorong Jasser Auda melakukan penelitian dengan menggunakan pendekatan multi disipliner dengan menggabungkan konsep-konsep yang relevan, yakni maqashid al-syariah beserta konsep-konsep ushul fiqih yang bertalian dengannya dengan menggunakan pendekatan teori sistem yang diambil dari ilmu pengetahuan Alam (sains.). Shifting paradigm dari sistem berfikir berdasar â€˜lllah (sebab) ke â€œMaqasidâ€ (tujuan). dalam hal ini, sistem adalah rangkaian unit-unit, bagian-bagian atau elemen-elemen dari berbagai â€˜fungsiâ€™ yang berbeda-beda tata kerjanya, yang kemudian membentuk satu kesatuan kerja yang terintegrasi secara utuh-menyeluruh. Maqasid al-Syariâ€™ah perlu memperhatikan dan memenuhi 6 (enam) elemen yang saling terkait: Cognitive, Wholeness, Openness, Interrelatedness, Multidimensionality dan purposefulness. Pendekatan System Analysis membantu pikiran manusia mengatur dunia nya (mengorganisir fakta dan pola pikir). dengan pendekatan system ini, Auda menawarkan formula ushul fikih baru yang mengacu pada â€œmaqasid al-Ammahâ€ untuk mewujudkan penerapan hukum Islam yang lebih kongkrit dan dinamisyang menjunjung tinggi nilai-nilai kesetaraan, kemaslahatan, keadilan, keseimbangan dan kebaikan.
Simulation of Gauged and Ungauged Streamflow of Coastal Catchments Across Australia
Authors: Bari Mohammed Abdul Abdul , Khan Urooj , Amirthanathan Gnanathikkam Emmanuel , Tuteja Mayank , Laugesen Richard Mark 
Published: November 2023

Australia is a unique continent surrounded by the ocean and the majority of catchments flow to the coast. Some of these catchments are gauged and others are ungauged. There are 405 gauged catchments covering 2,549,000 km2 across the coastal regions of 12 drainage divisions in Australia. Whereas there are 771 catchments conceptualised as ungauged covering additional 835,000 km2. The mean annual rainfall and PET and its spatial and temporal distribution vary significantly from one drainage division to another. We developed a continuous daily streamflow time series of all gauged and ungauged catchments from 1993 onwards. We applied the GR4J lumped conceptual model to these catchments. The performance of gauged catchments was analysed through (i) visual inspection of daily hydrographs, flow duration curves and daily scatter plots, and (ii) performance metrics including NSE and PBias. Based on the NSE and PBias, performance ratings of 80% and 96% of the models respectively were found &#039;good&#039;. There was no relationship found between the catchment area and model performance. The ungauged catchments were divided into four categories based on distance from potential donor catchments where observed data are available for GR4J model calibration, and Köppen climate zone. The total ungauged catchments represent 24.7% of the total drainage division areas. The streamflow from ungauged catchments was estimated using GR4J model based on the parameters of their donor catchments. Overall, runoff ratios from ungauged catchments were found to be higher compared to their donor gauged catchments, likely driven by their higher rainfall and less PET. This tendency was particularly evident in two drainage divisions – the Carpentaria Coast (CC) and Tanami-Timor Sea Coast (TTS) where ungauged areas comprised 51% and 43% respectively. The mean gauged annual streamflow varied significantly across drainage divisions – 230 GL from South Australian Gulf (SAG) to 146,150 GL in TTS. The streamflow from all ungauged catchments was estimated at 232,200 GL per year. Overall, the average streamflow from all drainage divisions, including gauged and ungauged areas, across the coastal regions of Australia was estimated at 419,950 GL per year. This nationwide estimate of streamflow dataset could potentially enhance our understanding of coastal processes and improvements of marine modelling systems and tools.
Management of Acute Bronchiolitis in Spoke Hospitals: Analysis and Outcome
Authors: Guidi Carla , Ragusa Neftj , Mussinatto Ilaria , Paola Francesca , Luotti Diego , Calosso Giulia , Rotondo Eleonora , Deut Virginia , Timeus Fabio Stefano , Brach del Prever Adalberto , Berger Massimo 
Published: November 2023

Bronchiolitis is an acute viral infection of the lower respiratory tract that affects infants and young children. Respiratory syncytial virus (RSV) is the most common causative agent, however other viruses can be the reason of the disease. We retrospectively reviewed the clinical features of infants aged less than 12 months referred to our Pediatric Units of Chivasso, Cirié and Ivrea for acute bronchiolitis requiring hospitalization over two consecutive bronchiolitis seasons. Patient-, disease-
and treatment related variables were analyzed in this retrospective study. We were able to show how with the high flow oxygen support (HFNC) only a very low number of children (8 out of 192) need to be trasferred to our HUB referral centers. The probability of success were 96% for all patients and 93% for RSV vs. 98% for non-RSV patients (P=NS). Factor associated to failure of treatment were age below 1 months and the failure of HFNC. The wide and increasing use of HFNC in pediatric inpatients improved management of bronchiolitis in Spoke hospitals, reducing transfer to a Hub hospital provided with Intensive Care Units.
WELLBEING METHODOLOGY IN SOCIAL AND HUMANITIES RESEARCH
Authors: Suriadi Jadi Suriadi 
Published: November 2023

This research delves into the intricate aspects of methodology, presenting a series of procedural steps utilized in empirical research titled "Wellbeing Methodology: A Comprehensive Approach to Evaluating Public Contentment Regarding Municipal Services in Bau Bau City, Southeast Sulawesi, 2023." Within this study, we employ the Wellbeing Methodology (WM), tailored to scrutinize public concerns and governmental policies, specifically concentrating on appraising public satisfaction with the services delivered by the municipal administration in Bau Bau City, Southeast Sulawesi, during the year 2023. WM offers a holistic framework that assesses diverse dimensions of public welfare, with a primary focus on the elements of Perception, Participation, and Acceptance (PPA). We have collected data, including respondent identification, PPA evaluation scores, and community input, which are presented in visual formats such as graphs and diagrams.
This study aims to explore residents' satisfaction levels regarding various government services and assess the significance of the Perception, Participation, and Acceptance (PPA) variables in shaping overall societal well-being, referred to as the "Index of Public Well-being". It addresses crucial research inquiries, bridges existing research gaps, and also solicits community feedback in the form of suggestions, recommendations, and critiques to pinpoint areas ripe for improvement.
The collected data will be leveraged to construct a Public Satisfaction Index, facilitating comparisons and discussions across diverse population segments. The data will undergo specific modes of analysis The data scores reveal a final score of 7.26 out of 9.0, indicating a highly positive interpretation. A total of 21 evaluation points were considered, all of which fall within the
significant range. However, it's noteworthy that approximately 8% of respondents provided lower scores (ranging from 1 to 4), warranting further investigation.
Additionally, this research endeavours to formulate a sustainability plan to ensure the continuous enhancement of community well-being. Through rigorous data analysis and widespread dissemination, this study contributes to a deeper understanding of public sentiment and the effectiveness of local government services, ultimately fostering improvements in governance and public welfare.