bluuebunny/crossref_metadata_2025_split huggingface dataset:
A bibliometric analysis of the top 100 most cited articles on corticospinal tract regeneration from 2004 to 2024
Authors: Saijilafu  , Ye Ling-Chen , Li Huanyi , Li Haokun , Lin Xinyi , Hu Kehui , Huang Zekai , Chimedtseren Chimedragchaa , Fang Linjun , Saijilahu  , Xu Ren-Jie 
Published: January 2025

ObjectiveHere, bibliometric and visual analytical techniques were employed to assess the key features of the 100 most cited publications concerning corticospinal tract (CST) regeneration.MethodsResearch was conducted within the Web of Science Core Collection to pinpoint the 100 most cited publications on CST regeneration. From these, comprehensive data encompassing titles, authorship, key terms, publication venues, release timelines, geographic origins, and institutional affiliations were extracted, followed by an in-depth bibliometric examination.ResultsThe 100 most cited publications were all published between 2004 and 2024. These seminal papers amassed an aggregate of 18,321 citations, with individual citation counts ranging from 83 to 871 and a median of 136 citations per paper. Schwab M. E., stood out as the most prominent contributor, with significant authorship in 9 of the 100 papers. The United States dominated the geographical distribution, accounting for 49 of the articles. With 17 publications, the University of California System led the institutional rankings. A thorough keyword analysis revealed pivotal themes in the field, encompassing the optic nerve, gene expression, CST integrity and regeneration, diffusion tensor imaging, myelin-associated glycoproteins, inhibitors of neurite outgrowth, and methods of electrical and intracortical microstimulation.ConclusionThis investigation provides a bibliometric analysis of CST regeneration, underscoring the significant contribution of the United States to this field. Our findings unveiled the dynamics and trends within the field of CST regeneration, providing a scientific foundation for advancing clinical applications. Building on this analysis, the clinical application of CST regeneration should be optimized through interdisciplinary collaboration, enabling the exploration and validation of a variety of therapeutic approaches, including the use of neurotrophic factors, stem cell therapies, biomaterials, and electrical stimulation. Concurrently, additional clinical trials are necessary to test the safety and efficacy of these therapeutic methods and develop assessment tools for monitoring the recovery of patients. Furthermore, rehabilitation strategies should be refined, and professional education and training should be provided to enhance the understanding of CST regeneration treatments among both medical professionals and patients. The implementation of these strategies promises to enhance therapeutic outcomes and the quality of life of patients with spinal cord injury (SCI).
3D-QSAR, design, molecular docking and dynamics simulation studies of novel 6-hydroxybenzothiazole-2-carboxamides as potentially potent and selective monoamine oxidase B inhibitors
Authors: Xie Dong , Tian Yongzheng , Cao Li , Guo Penghang , Cai Zhibiao , Zhou Jie 
Published: January 2025

Background6-hydroxybenzothiazole-2-carboxamide is a novel, potent and specific inhibitor of monoamine oxidase B (MAO-B), which can be used to study the molecular structure and develop new neuroprotective strategies.ObjectiveThe aim of this study was to create an effective predictive model from 6-hydroxybenzothiazole-2-carboxamide derivatives to provide a reliable predictive basis for the development of neuroprotective MAO-B inhibitors for the treatment of neurodegenerative diseases.MethodsFirst, the compounds were constructed and optimized using ChemDraw and Sybyl-X software. Subsequently, QSAR modeling was performed using the COMSIA method in Sybyl-X to predict the IC50 values of a set of novel 6-hydroxybenzothiazole-2-carboxamide derivatives. The ten most promising compounds were screened based on the IC50 values and tested for molecular docking. Finally, the binding stability and dynamic behavior of these compounds with MAO-B receptors were analyzed by molecular dynamics simulation (MD).ResultsThe 3D-QSAR model showed good predictive ability, with a q2 value of 0.569, r2 value of 0.915, SEE of 0.109 and F value of 52.714 for the COMSIA model. Based on the model, we designed a series of novel 6-HBC derivatives and predicted their IC50 values by the QSAR model. Among them, compound 31.j3 exhibited the highest predicted IC50 value and obtained the highest score in the molecular docking test. MD simulation results showed that compound 31.j3 was stable in binding to the MAO-B receptor, and the RMSD values fluctuated between 1.0 and 2.0 Å, indicating its conformational stability. In addition, energy decomposition analysis revealed the contribution of key amino acid residues to the binding energy, especially Van der Waals interactions and electrostatic interactions play an important role in stabilizing the complex.ConclusionIn this study, the potential of 6-hydroxybenzothiazole-2-carboxamide derivatives as MAO-B inhibitors was systematically investigated by 3D-QSAR, molecular docking and MD simulations. The successfully designed compound 31.j3 not only demonstrated efficient inhibitory activity, but also verified its stable binding to MAO-B receptor by MD simulation, which provides strong support for the development of novel therapeutic drugs for neurodegenerative diseases. These findings provide important theoretical basis and practical guidance for future drug design and experimental validation.
The temporal change of heat exposure and adaptation capacity in Chinese adults from 1994 to 2023
Authors: Ji Xiaohui , Tan Haomin , Huang Shaoli , Huang Zhongguo , Hu Jianxiong , He Guanhao , Jing Fengrui , Lin Ziqiang , Guo Mengen , Liu Tao , Ma Wenjun 
Published: January 2025

BackgroundStudies have found decreased heat effect and increased minimum mortality temperature (MMT) during the past decades. However, it is unclear whether heat exposure or temperature adaptation play an important role in this change.MethodsThis is a cross-sectional study. Data were collected from 3,094 respondents aged 31–64 years old based on online questionnaire. The Cochran-Armitage test for trend and Cochran–Mantel–Haenszel (CMH) test were used for the difference between three decades. The Chi square test was employed to compare the difference between different demographic subgroups during 2014–2023. Multivariate logistic regression model was used to analyze the risk factors of air conditioner ownership.ResultsMost respondents (94.6%) thought ambient temperature had been increasing, and 57.0% people thought climate change impacted their health. Long duration outdoors work (≥4 h) decreased from 36.01, 30.93 to 24.53% (Z = −9.80, p &lt; 0.01) and bicycling/walking decreased from 62.3, 27.9, to 9.7% (CMH value = 156.40, p &lt; 0.01) significantly during the last three decades. Temperature adaptation capacity increased with air conditioner ownership rates increasing from 25.40, 57.63 to 81.51% at home (Z = −44.35, p &lt; 0.01) and from 22.24, 57.47 to 80.51% in the office/school (Z = −45.95, p &lt; 0.01), and the older adult, women, people with low income, outdoor work, low education, and people from northern China had lower air conditioner ownership rates. The frequency of air conditioner usage when felt hot also escalated significantly both at home (from 42.6%, 54.9, to 63.4%, CMH value = 156.40, p &lt; 0.0001) and in the office/school (from 61.8, 63.1 to 72.7%, CMH value = 65.29, p &lt; 0.0001) during the same periods.ConclusionOur study found that most people perceived climate change and changed behaviors to adapt to heat. Heat exposure significantly decreased and temperature adaptation capacity significantly increased during the last decades. The findings implied that heat-related health risk and burden driven by global warming may not increase in the future.
Exploring the Genetic Potential for Multi-Resistance to Rust and Other Coffee Phytopathogens in Breeding Programs
Authors: Mariz Bruna Lopes , Caixeta Eveline Teixeira , Resende Marcos Deon Vilela de , Oliveira Antônio Carlos Baião de , Almeida Dênia Pires de , Alves Danúbia Rodrigues 
Published: January 2025

The application of marker-assisted selection in coffee breeding programs accelerates the identification and concentration of target alleles, being essential for developing cultivars resistant to multiple diseases. In this study, a population was developed from artificial crossings between Timor Hybrid and Tupi Amarelo, with the aim of promoting the pyramiding of resistance genes to the main diseases and pests of Coffea arabica: coffee leaf rust (CLR), coffee berry disease (CBD), cercospora, and leaf miner. Resistance was confirmed by nine molecular markers at loci associated with CLR (genes SH3, CC-NBS-LRR, RLK, QTL-GL2, and GL5) and with CBD (gene Ck-1). The resistance to CLR, cercospora, and leaf miner was evaluated using phenotypic diagrammatic scales. Mixed models estimated population superiority in 16 morphoagronomic traits over four agricultural years. The introgression of resistance alleles to CLR and CBD was identified in 98.6% of the population, with 29% showing pyramiding of five resistance genes. These pyramiding genotypes showed 100% resistance to the leaf miner and 90% to cercospora. The traits were grouped into univariate, bivariate, and trivariate repeatability models, with 11 significant ones. These results are indicative of genetic variability to be explored in the development of cultivars with multiple resistances and high agronomic potential.
CRISIS OF TRUST IN GOVERNMENT: THE ROLE OF PUBLIC RELATIONS IN ITS RESTORATION
Authors: Samoilenko Larysa , Sharyi Viacheslav , Zahrebelna Alina 
Published: January 2025

The article examines the importance of citizens' trust in state institutions in the context of modern public administration challenges. It delves into the negative consequences stemming from a lack of trust, which can significantly affect the effectiveness of management decisions, the legitimacy of political processes, and the overall stability of society. In particular, a deficiency of trust can lead to an increase in social tension, rising protest moods, and, as a consequence, the destabilization of the political situation.
The importance of public relations (PR) is emphasized as a strategic tool for managing communication and shaping a positive image of the state. The article underscores the necessity for two-way communication between the government and society, which is crucial for restoring trust during crises. PR professionals play a central role in this dynamic, as they are tasked with shaping and broadcasting messages that align with the needs and expectations of citizens. Their ability to effectively communicate government actions, intentions, and policies is essential for building and maintaining trust.
Additionally, the article provides an overview of the challenges organizations encounter under crisis conditions. It examines contemporary theories of crisis communication and suggests practical measures for enhancing public engagement. Various strategies are analyzed, which government institutions can adopt to ensure transparency, accessibility, and the timely dissemination of information to citizens.
Particular attention is paid to the experience of Ukraine, where statistical data reveal varying levels of trust in different state institutions. The article highlights the critical role of local authorities and the process of decentralization in fostering trust through active collaboration with civil society. Overall, it emphasizes the need for systemic changes in communication management approaches to secure political stability and promote economic development. Consequently, the key conclusions suggest that effective public relations can serve as a cornerstone for cultivating more trusting and stable relationships between the state and its citizens, ultimately enhancing the effectiveness of governance and public administration.
Памятливость и благодарность. Михаил Павлович Азанчевский: загадки личности, судьбы, последующего забвения
Authors: Климовицкий А.И. 
Published: January 2025

Посмертно публикуемая статья А. И. Климовицкого посвящена фигуре русского музыканта и музыкального деятеля М. П. Азанчевского (1839–1881), директора Санкт-Петербургской консерватории (1871–1876). Подчеркивается необходимость сохранения памяти об этом выдающемся человеке. В этой связи автор вспоминает о собственных усилиях, предпринятых на рубеже XX и XXI веков, но не получивших поддержки со стороны тогдашнего руководства Консерватории. Предложения Климо­вицкого касались, в частности, восстановления Стипендии имени Азанчевского и присвоения имени музыканта Научной библиотеке Консерватории. В статье приводятся исторические документы и излагаются факты, касающиеся присуждения соответствующей стипендии в конце XIX и начале XX века, а также получения Азанчевским звания Почетного библиотекаря в 1866 году. Вклад музыканта в создание консерваторской библиотеки не был забыт его потомками: сам А. И. Климовицкий в юности узнал полузабытое к тому моменту имя Азанчевского от Е. Е. Шведе (1894–1980), более четверти века возглавлявшей Библиотеку Ленинградской консерватории, и от А. М. Равикович (1892–1980), заведующей ее Иностранным кабинетом. Мемуарные заметки об этих женщинах, продолжательницах дела Азанчевского, естественно вплетаются в основной сюжет статьи, создавая уникальную в своем роде полифонию памятливости и благодарности.
The posthumously published article by A. I. Klimo­vitsky is devoted to the Russian musician M. P. Azanchevsky (1839–1881), director of the St. Petersburg Conservatory (1871–1876). The necessity of preserving the memory of this outstanding person is emphasized. In this connection, the author recalls his own efforts, undertaken at the turn of the 20th and 21st centuries, but not supported by the then management of the conservatory. Klimovitsky’s pro­posals concerned, in particular, the restoration of the Azanchevsky Scholarship and the naming of the Conservatory’s Scientific Library after the musician. The article presents historical documents and facts concerning the awarding of the scholarship in the late 19th and early 20th centuries, as well as Azanchevsky’s receiving the title of Honorary Librarian in 1866. The musician’s contribution to the creation of the Conservatory Library has not been forgotten by his descendants: in his youth, A. I. Klimovitsky himself learned the half-forgotten name of Azanchevsky from E. E. Shvede (1894–1980), who headed the Leningrad Conservatory Library for more than a quarter of a cen­tury, and A. M. Ravikovich (1892–1980), head of its Foreign Cabinet. Memoir notes about these women, continuers of Azanchevsky’s work, are naturally woven into the main plot of the article, creating a unique polyphony of remembrance and gratitude.
Неприятие непривычного. Предисловие к «Лексикону музыкальных инвектив»
Authors: Слонимский Н.Л. 
Published: January 2025

Впервые на русском языке публикуется Предисловие к «Лексикону музыкальных инвектив» (1953), составленному Николаем Леонидовичем Слонимским (1894–1995), российским и американским музыковедом, дирижером, лексикографом и компо­зитором, — сборнику критических высказываний о композиторах, начиная с Бетховена. В Предисловии, озаглавленном автором как «Неприятие непривычного», он сообщает, что лексикон включает «нелицеприятные, пристрастные, брюзгливые суждения, авторы которых, как правило, попадают пальцем в небо», и приводит высказывания из разных периодических изданий и книг. Перевод выполнен Ольгой Егоровой.
For the first time, the “Prelude” to “The Lexicon of Musical Invective,” written by Nicolas Slonimsky (1894–1995), a Russian and American musicologist, con­ductor, lexicographer and composer, will be published in Russian. It was originally published in 1953 and is the “anthology of critical assaults upon composers since the time of Beethoven.” In his introduction, titled “Non-Acceptance of the Unfamiliar,” the author informs that “the Lexicon of Musical Invective cites biased, unfair, ill-tempered, and singularly unprophetic judgments” and quotes the statements from various periodicals and books. The translation was made by Olga Egorova.
ОЦЕНКА ПРЕДЕЛОВ ЧУВСТВИТЕЛЬНОСТИ И НЕОПРЕДЕЛЕННОСТИ ЛОКАЦИИ МИКРОСЕЙСМИЧЕСКИХ СОБЫТИЙ ПРИ РЕГИСТРАЦИИ ОПТОВОЛОКОННЫМИ ИЗМЕРИТЕЛЬНЫМИ СИСТЕМАМИ В УСЛОВИЯХ НЕОПРЕДЕЛЕННОСТЕЙ СКОРОСТНОЙ МОДЕЛИ СРЕДЫ
Authors: Рыжов В.А. , Рыков А.П. , Хабаров А.В. , Скворцов И.В. , Емельянов Б.В. 
Published: January 2025

Цель данной статьи – рассмотреть особенности и перспективы локации микросейсмических событий с использованием оптоволоконного кабеля, установленного в скважине. На основе численных экспериментов и теоретических исследований проводятся оценки чувствительности и неопределенности локации событий, а также определяются максимальные расстояния, на которых возможно обнаружение событий с учетом погрешности в знании скоростной модели окружающей среды. В качестве опорной скоростной модели использована модель с Пильтун-Астохского нефтегазоконденсатного месторождения (НГКМ).
The purpose of this work is to assess specifics and perspectives of microseismic event localization using a fiber optic cable installed in a well. Based on numerical experiments and theoretical research, assessments of sensitivity and uncertainty in event localization are conducted, and the maximum distances for event detection are determined, taking into account errors in the knowledge of the velocity model of the surrounding environment. The reference velocity model utilized of the Piltun-Astokhskoye oil and gas condensate field.
МОДЕЛИРОВАНИЕ МАГНИТНЫХ И ПЛОТНОСТНЫХ ПАРАМЕТРОВ МЕТЕОРИТНОГО КРАТЕРА ОЗЕРА СМЕРДЯЧЬЕ
Authors: Кузнецов К.М. , Лыгин И.В. , Шевалдышева О.О. , Фадеев А.А. , Гудкова Т.В. 
Published: January 2025

Гипотеза о метеоритном происхождении озера Смердячье, расположенного в Шатурском районе Московской области, была выдвинута в 1980-х годах. Для ее проверки в январе 2024 года сотрудниками кафедры геофизических методов исследования земной коры геологического факультета МГУ имени М.В. Ломоносова выполнены комплексные магнитометрические и гравиметрические работы. Количественная интерпретация аномальных полей показала их соответствие модели кратера, включающей внешний слой метаморфизованных пород во фронте ударной волны и тело ударника. Результаты моделирования доказывают гипотезу метеоритного происхождения озера Смердячье.
The hypothesis about the meteoritic origin of Lake Smerdyachye, located in the Shatura district of the Moscow region, was put forward in the 1980s. To verify it, in January 2024, the staff of the Department of Geophysical Methods of Studying the Earth’s Crust of the Faculty of Geology of Lomonosov Moscow State University performed complex magnetic and gravity survey. Quantitative interpretation of anomaly fields showed their compliance with the model of crater, which includes the metamorphosed rocks outer layer in the shock wave front and the impactor body. The modelling results prove the hypothesis of Smerdyachye Lake meteoritic origin.
أبو سهل النوبختي والوثائق المبكرة عن عصر الغيبة
Authors: الاستاذ المساعد الدكتور محمد جواد نور الدين فخر الدين  
Published: January 2025

المقدمة:
تعد غيبة الإمام الثاني عشر "الإمام المهدي" من أهمّ المسائل الأصيلة في تاريخ الفكر الإسلامي، وأكثر القضايا جدلية في العصر الحديث ، على الرغم من انها موضع اتفاق بين غالبية المذاهب والفرق الإسلامية ، وبنفس الوقت احتوتها الديانات السماوية الأخرى (اليهودية والمسيحية) وكذلك الديانات الوضعية لكن جاءت بألفاظ ومصطلحات مختلفة كالمنقذ أو المخلص([i]) ، والأمر بتصوري حول حقيقة الاختلاف ناشئ من سوء تفسير وتطبيق ، وليس من النصوص نفسها.

([i]) لمزيد من العلمومات حول هذا الموضوع ينظر على سبيل المثال من الدراسات : صديقي، محمد الناصر، فكرة المخلِّص بحث في الفكر المهدوي، (بيروت، دار جداول، ١٤٣٤هـ/٢٠١٢م) ، الفرطوسي، صلاح، المخلص عند اليهود والنصارى والمسلمين، (إيران، شمس خلف السحاب، ١٤٣٤هـ/٢٠١٣م) ، حليم، حسب الله عوض، عظمة المخلص وروعة الخلاص، (مصر، دار الأخوة للنشر، ١٤٣٠هـ/٢٠٠٨م) ، طويلة، عبد الوهاب عبد السلام، المسيح المنتظر ونهاية العالم، (بيروت، دار السلام، ١٤٢٤هـ/٢٠٠٣م).
المظاهر السياسية والحضارية للنساء في الدولة الفاطمية نماذج مختارة (دراسة تاريخية)
Authors: الاستاذ المساعد الدكتور محمود شاكر مشعان  
Published: January 2025

الملخص:
إنّ حضور النساء في هرم الدولة الفاطمية له امتداد في موطنها الأصلي أي قبل فتح مصر سنة (358هـ/969م) وبناء مدينة القاهرة كعاصمة جديدة للدولة الفاطمية، إذ كان للنساء أثر واضح في جميع شؤون الحياة، على الرغم من التقاليد التي فرضتها ظروف المجتمع، ولعبت نماذج من نساء القصر دوراً كبير في السياسة على الصعيد الداخلي والخارجي، ففي السياسة الداخلية كان أثرهن واضحاً في تثبيت السلطة الفاطمية في مصر من خلال الدور الذي أدينّه في التأثير على مجرى الأحداث لصالح الخلافة، أما على الصعيد الخارجي فتمكنت النساء من عقد المعاهدات الدولية، ولا أنسى دور النساء الفاطميات وما له من أثر في نشر الدعوة الفاطمية، فضلاً عن الأثر الكبير في مجال النهضة العمرانية، وكان دور نساء الدولة الفاطمية إيجابياً، إذ حافظنّ على قوة الدولة الفاطمية وحرصنّ على بقاء الخلافة في البيت الفاطمي.
ACUPUNTURA NOS SERVIÇOS PÚBLICOS E PRIVADOS: VISÃO DOS ESTUDANTES DA GRADUAÇÃO DE MEDICINA
Authors: Nathalia Amaro Schmidt  , Shinkawa Cassini Renan , Terezinha Alves Rezende Katia , Franco da Rocha Tonhom Sílvia , Roberto Bissoto João 
Published: January 2025

A inclusão da acupuntura como uma das práticas contidas na Política Nacional de Práticas Integrativas e Complementares (PNPIC) do Sistema Único de Saúde (SUS) permite refletir sobre a presença dessa especialidade em instituições de saúde públicas e privadas. Nesse sentido, questiona-se: como se dá a inserção das Práticas Integrativas e Complementares (PICs), em especial, a acupuntura, nos serviços públicos e privados, na visão dos estudantes de graduação de medicina? Analisar a inserção e o acesso à acupuntura nos serviços de saúde públicos e privados no contexto brasileiro, na perspectiva dos estudantes de medicina. A investigação é de caráter qualitativo, utilizando-se a entrevista semiestruturada como instrumento de coleta de dados. Os graduandos de medicina das 5ª e 6ª séries de três instituições públicas do Sudeste do Brasil foram os participantes. Empregou-se a Análise de Conteúdo, modalidade Temática. Consta-se que esta pesquisa foi aprovada pelo Comitê de Ética em Pesquisa em Seres Humanos (CEP) da instituição dos pesquisadores. Os dados revelam que não há conhecimento consolidado quanto à disponibilidade dessa prática no âmbito do SUS, além disso, os estudantes contam que, mesmo quando existe a especialidade no serviço, o acesso é precário. Quanto ao setor privado, ressalta-se também essa falta de contato, porém os estudantes possuem ciência de que esse serviço é oferecido, o qual é caracterizado por estar mais disponível, em comparação ao SUS. No entanto, os entrevistados identificam empecilhos ao acesso à acupuntura no âmbito da Saúde Suplementar. A pesquisa qualitativa viabilizou uma análise mais aprofundada sobre a temática e, frente às fragilidades apresentadas nos resultados, espera-se uma maior abordagem dessa especialidade em ambos os cenários, incluindo no contexto acadêmico, visto que se reconhece que é uma forma de tratamento com retorno positivo aos usuários.