bluuebunny/crossref_metadata_2025_split huggingface dataset:
Targeted Test and Treat at Point of Entry to Reduce Importation of Malaria Parasites: A Systematic Review
Authors: Martí Coma-Cros Elisabet , Tusell Maria , Bhamani Beena , Mithi Vita , Serra-Casas Elisa , Williams Nana Aba , Lindblade Kim A. , Allen Koya C. 
Published: December 2023

ABSTRACT.
As countries approach malaria elimination, imported cases of malaria make up a larger proportion of all cases and may drive malaria transmission. Targeted test and treat (TTaT) at points of entry (POEs) is a strategy that aims to reduce the number of imported infections in countries approaching elimination by testing and treating individuals at border crossings. No evidence has been systematically collected and evaluated to assess the impact and operational feasibility of this strategy. This systematic review gathered empirical evidence on the effectiveness of the intervention, contextual factors, and results of modeling studies that estimate its potential impact. Bibliographic searches were conducted in March 2021 and updated in April 2022, and a total of 1,569 articles were identified. All study designs were included, but none of them were intervention studies set up to measure the impact of TTaT at POEs. Seven nonrandomized observational studies were eligible for assessment of outcome data in terms of describing the extent of positive cases among people crossing borders. Also included in the review were three studies for assessment of acceptability and feasibility of the intervention and three for assessment of mathematical modeling. The positivity rates reported in the seven studies ranged between 0.0% and 70.0%, which may be attributable to the different settings and operational feasibility. Overall, there is limited evidence of the effect of TTaT at POEs on the prevalence of infection, and the certainty of the evidence was very low owing to critical risk of bias, serious inconsistency, and serious indirectness.
Estética y Dominación: El Impacto de Schopenhauer y Nietzsche en la desvalorización estética de la Mujer en el Siglo XX:
Authors: Seco Martínez Jose María 
Published: December 2023

El pensamiento de Nietzsche y Shopenhauer será decisivo en el diseño de un nuevo estereotipo femenino, vinculado a una idea de la mujer especialmente exagerada del mal, que acabará poblando a través de la bohemia artística y literaria, el imaginario estético del siglo XX. Su filosofía servirá de aglutinante para muchos escritores y artistas e incidirá decisivamente en el estado espiritual de su época. Emerge así una nueva imagen de la mujer más degradada y menospreciativa, que ahora representa, no ya el temor masculino hacia lo femenino - una constante en la historia - sino el horror a ese otro femenino no explorado, que conculca los límites que la moral y la cultura patriarcales le han asignado.
Adherencia a Control Prenatal de Gestantes que Asisten al ICBF – Asociación Esperanza y Progreso Primera de Mayo
Authors: Lozano Beltrán Jenny Amparo , Yopasa Cárdenas Carolina , Cetares Romero María Alejandra 
Published: December 2023

Objetivo. Promover la adherencia al control prenatal en mujeres gestantes asistentes a la Asociación Esperanza y Progreso. Metodología. Se realizó una aproximación a mujeres gestantes en contextos de vulnerabilidad, asistentes al Instituto Colombiano de Bienestar Familiar - ICBF, con aplicación de pre test y post test en cada sesión educativa realizada; se tuvo en cuenta la experiencia del semillero en las intervenciones. Resultados y Conclusiones. Se considera necesaria la realización de sesiones educativas desde el sistema de salud, para que desde otros actores intersectoriales se puedan detectar adherencias significativas a seguimientos en salud, tanto en el control prenatal, como en todas las etapas del curso de vida, permitiendo incidir positivamente en la salud de las mujeres gestantes en condiciones de vulnerabilidad social.
Tratamiento combinado con metotrexato y prednisona en pacientes con alopecia areata total y universal
Authors: Minaudo Carla 
Published: December 2023

Estudio multicéntrico, aleatorizado, doble ciego realizado en Francia de 2014 a 2016, en pacientes de 18 a 70 años con alopecia areata total y universal crónica (con al menos 6 meses de evolución). Se incorporaron casos en los que fracasaron los tratamientos tópicos y sistémicos previos, a excepción del metotrexato (MTX).
Se incluyeron 89 pacientes y se realizaron dos fases sucesivas de 6 meses cada una. En la primera, los pacientes fueron aleatorizados para recibir tratamiento con MTX 20-25 mg semanales versus placebo de MTX. Los que tuvieron índices de recrecimiento capilar mayores del 25% se mantuvieron con el mismo tratamiento. Aquellos con una respuesta menor del 25% fueron reasignados a MTX + prednisona (20 mg/d durante 3 meses y luego 15 mg/d durante 3 meses) frente a MTX + placebo de prednisona. La duración total del protocolo fue de 12 meses.
Los pacientes fueron evaluados por cuatro expertos internacionales independientes. El objetivo primario fue la respuesta completa o casi completa (RC), entendida como una recuperación del cabello superior al 90% (puntaje SALT < 10) a los 6 meses.
Se observó que el MTX como monoterapia no tuvo una eficacia suficiente. La combinación con dosis bajas de prednisona fue más eficaz y alcanzó la RC hasta en el 31% de los pacientes.
Se documentó el seguimiento de 7 pacientes que habían obtenido RC durante 70,3 meses, 5 de ellos mantuvieron la respuesta con un puntaje SALT entre 40 y 0. Tres pacientes suspendieron el tratamiento y 4 continuaron con una dosis promedio de 8,7 mg de prednisona diarios y 11,6 mg de MTX semanal.
El inicio de la respuesta se observó a los 3 meses en los pacientes con la terapia combinada, mientras que hubo un retraso mayor en los que usaron MTX solo.
Los autores señalan que los niveles de respuesta fueron comparables con los obtenidos en el estudio de King et ál. con el baricitinib.
Mevlânâ Müzesi Arşivi Belgelerine Göre Yozgat Mevlevîhânesi ve Sâlih Sabrî Dede (ö.1329/1914)
Authors: KÜÇÜK Sezai 
Published: December 2023

XIV. asırda Konya’da kurulan Mevlevîlik, zaman içinde teşkilatlanmış ve başta Anadolu olmak üzere Osmanlı Devleti sınırları dâhilinde mevlevîhaneler vasıtasıyla yayılmıştır. Sâlih Sabrî Dede tarafından Yozgat’ta kurulan Yozgat Mevlevîhanesi de bunlardan biridir. Bu makalede XX. asrın başlarında faaliyete geçen Yozgat Mevlevîhanesi’nin kuruluşu ile mevlevîhanenin kurucusu Salih Sabrî Dede’nin hayat hikâyesi ve mevlevîhanedeki faaliyetleri ele alınmıştır. Konya Mevlânâ Müzesi Arşivi’nde bulunan Yozgat Mevlevîhanesi ile ilgili Berat, Vakfiye, arîza, emirnâme, mektup ve resmi yazışma türü evraklardan elde edilen bilgiler ve konu ile ilgili Mevlevîlik kaynakları ve diğer kaynaklardan toplanan malumatlar değerlendirilerek Yozgat Mevlevîhanesi ve kurucusu Sâlih Sabrî Dede ve faaliyetleri ortaya konulmuştur.
Yozgat Mevlevîhanesi ile ilgili akademik olarak yapılan ilk ve tek çalışma olan bu makalede; Yozgat Mevlevîhanesi’nin tarihi ortaya çıkartılmış, bir Mevlevî şeyhi olarak Sâlih Sabrî Dede’nin hayat hikâyesi ve mevlevîhanedeki çok yönlü faaliyetleri tespit edilmiş, ayrıca ulaşılan ve değerlendirilen bilgilerle XX. asrın başlarında Osmanlı sosyal ve kültürel hayatına katkı sağlanmıştır.
Evaluation of antibiotic susceptibility in enterococci isolated from blood culture samples
Authors: KOCA Özlem , ER Halil , ÇEKİN Yeşim 
Published: December 2023

Aims: Increased vancomycin resistance in enterococci is an important cause of life-threatening bloodstream infections in hospitalized patients. The aim of this study is to determine the antibiotic susceptibility rates of Enterococcus strains isolated from blood cultures in hospitalized patients in Antalya Training and Research Hospital.
Methods: The antibiotic resistance rates of Enterococcus strains isolated from blood cultures of patients hospitalized in the service and intensive care units (ICU) between 1 January 2018 and 30 December 2022 were examined retrospectively. Blood samples were studied with the BacT/ALERT 3D culture system (Biomerieux, France). Bacterial identification was performed using conventional methods, Matrix Assisted Laser Desorption-Ionization Time-of-Flight Mass Spectrometer (MALDI-TOF MS) and VITEK 2 (Biomerieux, France) systems. Antimicrobial susceptibility tests were performed with VITEK 2 (Biomerieux, France) systems. Ampicillin, vancomycin, teicoplanin, high-level gentamicin resistance (HLGR) and linezolid susceptibility of isolated strains were evaluated according to the European Committee on Antimicrobial Susceptibility Testing (EUCAST) criteria. Vancomycin minimal inhibitory concentration (MIC) values of vancomycin resistant strains were studied by microdilution gradient strip test (Bioanalyse).
Results: A total of 623 strains of enterococci were isolated from blood culture samples. Of the enterococci, 305 (48.9%) were identified as Enterococcus faecalis, 281 (45.6%) Enterococcus faecium, 12 (1.9%) Enterococcus avium, 11 (1.8%) Enterococcus gallinarum, 7 (1.2%) Enterococcus casseliflavus, 2 (0.4%) Enterococcus durans and 1 Enterococcus hirae (0.2%). Ampicillin and HLGR resistance rates of isolated E. faecalis strains were 11 (3.6%) and 72 (23.6%), respectively, and all strains were found to be susceptible to vancomycin, teicoplanin and linezolid. The ampicillin, vancomycin, teicoplanin and HLGR resistance rates of E. faecium strains were determined as 229 (81.5%), 36 (12.8%), 30 (10.7%) and 142 (50.5%), respectively, and all strains were found to be susceptible to linezolid.
Conclusion: In infections caused by enterococci, identification and determination of antibiotic susceptibility rates according to culture antibiogram results would be the right approach. Knowing the current susceptibility rates of enterococci isolated from blood culture samples in our hospital will contribute for clinicians' planning of empirical treatment.
Colonoscopic evaluation of acromegalic patients: a single center experience
Authors: EMÜR GÜNAY Yasemin , DURAK Serdar , COŞAR Arif Mansur , ERKUT Murat , FİDAN Sami 
Published: December 2023

Aim: To investigate the importance and necessity of colonoscopic screening in patients with acromegaly.
Methods: This study included 82 patients with acromegaly and, 82 healthy individuals as the control group who underwent screening colonoscopy in the Gastroenterology Department of Karadeniz Technical University, between January 2008-January 2021.
Results:The mean age of the patients was 45.71 ± 12.61 years at the time of acromegaly diagnosis. 51.2% (n=42) of patients were female. Abnormal findings including evidence of polyps, and inadequate bowel preparation were significantly more common in the acromegaly group than the control(p
Experimental study: effects of folic acid, vitamin C, and vitamin E on fat graft survival
Authors: OKYAY Mehmet Fatih 
Published: December 2023

Aim: This study explores the potential of folic acid (vitamin B9), ascorbic acid (vitamin C), and α-tocopherol (vitamin E) to enhance fat graft survival.
Material and Method: The dorsal regions of the Sprague-Dawley rats (n=10) were divided into four quadrants as inguinal fat donor recipient sites. After incubation, fat grafts were placed into sites (0.9% NaCl-left cranial, vitamin B9-right cranial, vitamin C-left caudal, and vitamin E-right caudal). At the end of the third month, fat grafts were harvested. Fat grafts were evaluated immunohistochemically with perilipin to reveal viability.
Results: Folic acid, vitamin C, and vitamin E were shown improved fat graft survival rate with perilipin (p
Reviewing YouTube as a source of information on bipolar disorder
Authors: ALTUNSOY Neslihan 
Published: December 2023

Aims: Assess the qualities and reliabilities of Turkish and English YouTube videos providing information about Bipolar Disorder and how beneficial they are for viewers in our study.
Methods: In our study, a total of 120 videos were evaluated, with 60 in Turkish and 60 in English, which appeared on the first three pages of search results. Videos that were entirely or partially quoted and repeated were not rated, but videos with an earlier publication date were included. A total of 80 videos were included in the study. Videos published in Turkish and English were watched and rated by a psychiatrist.
Results: Significant portion of the videos were uploaded by healthcare institutions (29.3%) or a professional (psychiatrist/psychologist) (28%). When all videos were evaluated, the median Modified DISCERN score was 3.48 (IQR: 1), the median GQS (Global Quality Scale) score was 3.67 (IQR: 1), the median total video content score was 4.00 (IQR: 2), and the median VPI (Video Power Index) score was 67.14 (IQR: 207).When comparing the scales used to assess the quality of videos, it was found that the VPI score (p&lt;0.001) was significantly higher in English-language videos compared to Turkish-language videos, while the GQS score (p=0.116) and the modified DISCERN scale score (p=0.594) were similar
Conclusion: It was observed that the examined videos reached an average of 70,000 views, with the highest reaching approximately 13.5 million views. These data demonstrate the significant role of the internet and YouTube in providing access to health information for patients. In this study, it was determined that YouTube videos related to Bipolar Disorder have an average to good quality and reliability.
Entre sequías y huracanes en Cuba. Burriel, un Acueducto para Matanzas (1800-1872)
Authors: Atencia Gil Esther 
Published: December 2023

La sequía, como amenaza de impacto lento asociada a riesgos y desastres, es un fenómeno extremo de difícil cuantificación y complicada delimitación temporal cuyos efectos destructivos han incidido directamente en el desarrollo socioeconómico del país o región afectados. Por ello, la respuesta de la sociedad no ha sido siempre la misma ni se han podido implementar medidas de forma inmediata.En el presente estudio, teniendo en consideración la globalidad del fenómeno en otras zonas, se analizan tres episodios de sequía más o menos intensos ocurridos en Cuba durante la primera mitad del siglo XIX, detallando sus efectos concretos en la provincia de Matanzas. Como medidas adoptadas, destacan las tradicionales “rogativas pro pluvia” y los proyectos de canalización de aguas para el abastecimiento de la ciudad que culminaron con la inauguración del Acueducto Burriel en 1872, conocido como Acueducto de Matanzas, con gran impacto en la sociedad matancera del momento.
A IMPORTÂNCIA DA SAÚDE COLETIVA SOBRE O CONTROLE E PREVENÇÃO DE PATOLOGIAS BUCAIS EM CRIANÇAS
Authors: Santos Samuel Balduino da Silva , Cabral Antonio Neto Leite , Yamashita Ricardo Kiyoshi 
Published: December 2023

A saúde bucal infantil é uma preocupação relevante para a Odontologia na prevenção de doenças bucais. A importância da Saúde Coletiva na odontologia relacionada as crianças, exibem um grande desafio presente nos tempos de hoje. O objetivo geral da pesquisa é analisar por meio de uma pesquisa bibliográfica e descritiva, os fatores que a saúde coletiva na odontologia podem atuar como meio de ajudar na regressão de patologias e lesões bucais em crianças, como também observar o comportamento dos cirurgiões dentistas na educação de saúde bucal e prevenção como a cárie entre outros fatores. Durante a pesquisa, foram elencados fatores que interferem diretamente nessa problemática. A idade ideal para os primeiros atendimentos é ainda no primeiro ano de vida devido a erupção dentária decídua ocorrer a partir do 6° mês de vida. Dessa forma, conclui-se que as ações de Saúde Coletiva estão voltadas para promoção, prevenção e recuperação da saúde levando em consideração os determinantes sociais da saúde e todos os fatores que podem interferir na saúde bucal infantil, buscando minimizar esses fatores agravantes e desencadeadores das principais patologias bucais em crianças.
Vivre, pour vivre ensemble
Authors: Nicolaï Jean-Paul 
Published: December 2023

Selon Paul Ricœur, « l’anthropologie est devenue une tâche urgente de la pensée contemporaine ». Celle qu’il élabore dans l’ensemble de son œuvre repose sur sa phénoménologie herméneutique (dont l’originalité tient notamment à l’héritage qui lui vient de la philosophie réflexive), au point que cette dernière suffit selon nous à en dessiner les grandes lignes. Elle permet de doter le monde de régularités qui le rendent habitable et de doter chaque homme d’un soi. Elle prend aussi à bras le corps les difficultés de l’intersubjectivité qu’Edmund Husserl ou Martin Heidegger avaient laissé non résolues et fait de cette intersubjectivité une clef de sa philosophie. L’homme est alors plus qu’un habitant du monde : il habite une cité qu’il contribue à édifier. Le thème du « nouveau » permet de consolider l’une des leçons que l’on peut tirer de l’œuvre de Ricœur : pour vivre ensemble, il faut vivre. L’anthropologie ricœurienne ne réclame alors aucune éthique ajoutée pour que cet élan vitaliste apparaisse via sa phénoménologie herméneutique.
El nacionalismo ruso de Putin ¿un legado soviético?
Authors: Faraldo José María 
Published: December 2023

El presente artículo parte de los discursos de justificación de la guerra de Ucrania y los sigue en retrospectiva para buscar el origen de buena parte del nuevo proyecto imperial de Vladimir Putin. Las preguntas principales a las que intento responder son: ¿cuánto hay de soviético en este nuevo nacionalismo? ¿El expansionismo imperial pretende volver a la URSS o reconstruir el Imperio de los Zares? ¿Qué hay de nuevo y original en esta construcción ideológica? En el contexto de la dictadura actual ¿podemos hablar de un nuevo totalitarismo?
Verticalidades e horizontalidades na constituição dos lugares: proposta metodológica para estudo de empresas de food delivery a partir dos dois circuitos da economia urbana
Authors: Nobre Carlos Eduardo 
Published: December 2023

Propomos uma metodologia para estudo de empresas de food delivery a partir dos dois circuitos da economia urbana. Tal metodologia reconhece a necessidade de compreensão do chamado capitalismo de plataforma e seu corolário – a uberização do setor de serviços – como uma das manifestações da modernização tecnológica e de seus rebatimentos na economia política da cidade. Nesse sentido, fundamentamos a metodologia a partir das noções de verticalidade, horizontalidade, tecnoesfera, psicoesfera e na proposição teórica dos dois circuitos da economia urbana. Destacamos que essa metodologia foi desenvolvida e aplicada em pesquisa que teve como objetivo compreender a ação das empresas de food delivery na cidade de São Luís, MA, no ano de 2020, e cujos resultados são discutidos, principalmente, em Aguiar (2021) e Nobre et al. (2023).
Palavras-chave: Método Geográfico. Circuitos da Economia Urbana. Capitalismo de Plataforma. Food Delivery.
Morphofunctional changes in the reproductive organs of females against the background of the use of a phytopreparation (experimental study)
Authors: Boyko T. V. , Ogurnoy I. V. , Koshkarev M. V. 
Published: December 2023

The paper presents the results of the assessment of morphological changes in the uterus and ovaries of laboratory animals against the background of the introduction of therapeutic doses of a multifunctional phytopreparation, which includes alcohol extracts from plants: white hellebore (Veratrum album), dioecious nettle (Urtica dioica), yarrow (Millefolii herba) and has rumination, uterotonic, hemostatic and anti-inflammatory effects. Therapeutic doses for cows were tested, which for rats amounted to 0.2 ml per head. The phytopreparation was adminitered subcutaneously three times, every other day. The control group rats were subcutaneously injected with a saline solution of sodium chloride (NaCI 0.9%) according to the same scheme. The methods of digital microscopy were used in the study of micropreparations. Morphometric analysis of the histoarchitectonics of the uterus revealed a statistically significant increase in the diameter of the cross-section of the uterus of female rats of the experimental group by 25.8% (p≤0.05) compared with the control group due to an increase in the epithelial by 24.5% (p≤0.05) and the endometrial lamina of the uterine mucosa by 32% (p≤0.05), which indicates on increasing the secretory activity of the epithelial cover of the uterus. In the experimental group of rats treated with phytopreparation, a significant increase of 46% (p<0.05) in the number of primordial follicles was noted. There was also a tendency to increase the number of primary – by 36.3%, secondary – by 41.7%, tertiary – by 75% of follicles and yellow bodies – by 22.2% in rats of the experimental group compared with the control indicators. Quantitative indicators of the follicular composition of the ovaries of rats of the experimental group and an increase in the follicle aging coefficient by 60% (p≤0.05) indicate stimulation of the ovarian reserve against the background of the use of phytopreparation.
The anthelmintic efficacy of the drug Expresstabs in helminthiasis of dogs
Authors: Tokarev A. N. , Tokareva O. A. 
Published: December 2023

The purpose of the research is to study the effectiveness of the drug ExpressTabs tested on dogs infected with helminths. The drug contains spinosad, praziquantel and moxidectin as active ingredients. Animals of mixed breeds of both sexes aged from 7 months to 2 years were selected for the experiments. Experimental and control groups of dogs with toxocariasis, toxascariasis and dipylidiasis were formed. ExpressTabs was administered to dogs individually, once, orally in a mixture with food or immediately after feeding (on the root of the tongue or with a treat) in a minimum dose of 30 mg of spinosad, 0.2 mg of moxidectin and 5 mg of praziquantel per 1 kg of animal weight. Animals in the control groups were not given tablets. A control examination in the case of dipylidiasis was carried out on the second day then if the animal continued to remain in the hospital once a week. For toxocariasis and toxascariasis fecal examination was carried out on day 7 then on days 14, 21 and 28. The drug ExpressTabs showed high (100%) effectiveness in the treatment of dogs with toxocariasis, toxaccariasis and dipylidiasis. In one animal re-infection with toxocariasis was observed because helminth eggs were again detected on day 28 in the control study. Taking into account the development cycle of parasites it is obvious that re-infection occurred no later than a week after the experimental deworming with ExpressTabs. At recommended doses the drug did not cause unwanted side effects.