bluuebunny/crossref_metadata_2025_split huggingface dataset:
Retrieval of autobiographical memory in Alzheimer's disease: Relation to volumes of medial temporal lobe and other structures
Authors: Gilboa Asaf , Ramirez Joel , Köhler Stefan , Westmacott Robyn , Black Sandra E. , Moscovitch Morris 
Published: May 2005

AbstractThe representation of autobiographical memory is distributed over a network of brain structures, with the medial temporal lobe (MTL) at its epicenter. Some believe that, over time, all memories become independent of their MTL component (“consolidation theories”). Others have suggested that this is true only of semantic memory, while episodic aspects of autobiographical memories are dependent on the MTL for as long as they exist, such as multiple trace theory (MTT). In the present study, the volumes of 28 brain regions, including the MTL, and their relation to autobiographical memory were investigated in a group of patients with Alzheimer's disease with varying degrees of retrograde memory loss as assessed by the Autobiographical Memory Interview (AMI). We used the multivariate analysis method of partial least squares (PLS) to assess patterns of atrophy that can lead to retrograde amnesia. We found that different aspects of autobiographical memory were associated with different patterns of tissue loss. Personal semantics were related to a pattern of bilateral anterior and posterior lateral temporal cortex degeneration, more pronounced on the left, as well as right frontal degeneration. Autobiographical event memory (“episodic”) was associated with combined atrophy in bilateral MTL and anterior lateral temporal neocortex, more pronounced on the right. This pattern was invariant for memories from childhood, early adulthood, and recent memories, in line with the predictions of MTT, suggesting that MTL tissue is crucial for retrieval of episodic memories regardless of their age. © 2005 Wiley‐Liss, Inc.
MDSIMAID: Automatic parameter optimization in fast electrostatic algorithms
Authors: Crocker Michael S. , Hampton Scott S. , Matthey Thierry , Izaguirre Jesús A. 
Published: May 2005

AbstractMDSIMAID is a recommender system that optimizes parallel Particle Mesh Ewald (PME) and both sequential and parallel multigrid (MG) summation fast electrostatic solvers. MDSIMAID optimizes the running time or parallel scalability of these methods within a given error tolerance. MDSIMAID performs a run time constrained search on the parameter space of each method starting from semiempirical performance models. Recommended parameters are presented to the user. MDSIMAID's optimization of MG leads to configurations that are up to 14 times faster or 17 times more accurate than published recommendations. Optimization of PME can improve its parallel scalability, making it run twice as fast in parallel in our tests. MDSIMAID and its Python source code are accessible through a Web portal located at http://mdsimaid.cse.nd.edu. © 2005 Wiley Periodicals, Inc. J Comput Chem 26: 1021–1031, 2005
Peptide sequencing through N‐terminal phosphonylation and electrospray ionization mass spectrometry
Authors: Bao Jiangyin , Ai Huiwang , Fu Hua , Jiang Yuyang , Zhao Yufen , Huang Cheng 
Published: May 2005

AbstractPeptides were phosphonylated at their N‐termini by reacting with ethoxyphenylphosphinate in the presence of triethylamine and tetrachloromethane under mild conditions. The phosphonylated peptides were analyzed by tandem electrospray ionization mass spectrometry. N‐Terminal phosphonylation selectively increased the intensities of bn‐type ions relative to other ion types. The resulting simplified mass spectra clearly show the sequential loss of amino acid residues from the C‐termini of peptides, providing a convenient and rapid method for peptide sequencing. Copyright © 2005 John Wiley & Sons, Ltd.
Selenoketene (H2CCSe)+• and selenoketyl cumulene (HCCSe)+ ions and their neutral counterparts: a tandem mass spectrometric and computational study
Authors: Nagi Reddy P. , Srikanth R. , Bhanuprakash K. , Srinivas R. 
Published: May 2005

AbstractDissociative electron ionization (70eV) of selenophene (C4H4Se) generates m/z 106 ions of composition [H2, C2, 80Se]+• and m/z 105 ions of [H, C2, 80Se]+. From tandem mass spectrometric experiments, Density Functional Theory (DFT) and ab initio calculations, it is concluded that these ions have the structure of selenoketene H2CCSe+• (1a+• )and selenoketyl HCCSe+ (2a+) ions respectively. The calculations predict that selenoketene ion 1a+• is separated by high energy barriers from its isomers selenirene (H$\catcode`@=11 \def\overlsqmatrix#1{\null\vbox{\normalbaselines\m@th \ialign{\hfil$##$\hfil&&\quad\hfil$##$\hfil\crcr \mathstrut\crcr\noalign{\kern-\baselineskip} #1\crcr\mathstrut\crcr\noalign{\kern-\baselineskip}}}} \newdimen\rulwidth \def\downsqbrace#1{\setbox1=\hbox{#1} \rulwidth=\wd1\advance \rulwidth by -6pt \raise3pt\hbox{$\overlsqmatrix{\vrule height5pt\kern-0.5pt\raise5pt\hbox to \rulwidth{\hrulefill}\kern-0.5pt\vrule height5pt\cr\noalign{\vskip-3pt}\hbox{#1}\cr\noalign{\vskip-5pt}}$}} \catcode`@=12 \downsqbrace{{\rm CCHS}}$e)+• 1b+•, ethyne selenol (HCCSeH)+• 1c+•, (CCHSeH)+• 1d+• and (CCSeH2)+• 1e+•. The selenoketyl ion 2a+ is separated by high barriers from its isomers (CCHSe)+ 2b+, and (CCSeH)+ 2c+. Neutralization‐reionization mass spectra (NRMS) of these structurally characterized ions confirmed that the corresponding neutral analogues, selenoketene H2CCSe 1a and selenoketyl radical HCCSe 2a• are stable in the rarefied gas phase. The relative, dissociation, and isomerization energies for selenoketene and selenoketyl ions and neutrals studied at B3LYP/6–31G(d,p) and G2/G2(MP2) levels are used to support and interpret the experimental results. Copyright © 2005 John Wiley & Sons, Ltd.
Functional expression of the ecto‐ATPase NTPDase2 and of nucleotide receptors by neuronal progenitor cells in the adult murine hippocampus
Authors: Shukla Varsha , Zimmermann Herbert , Wang Liping , Kettenmann Helmut , Raab Sabine , Hammer Klaus , Sévigny Jean , Robson Simon C. , Braun Norbert 
Published: May 2005

AbstractAn astrocyte‐like cell population corresponding to residual radial glia represents the neuronal progenitors of the adult mammalian hippocampus. We show that radial glia‐like cells of the dentate gyrus express surface‐located ATP‐hydrolyzing activity and are immunopositive for NTPDase2. This enzyme hydrolyzes extracellular nucleoside triphosphates such as ATP and UTP to their nucleoside diphosphates and is thus involved in the control of signaling via P2 receptors. NTPDase2 is expressed from embryonic day 17 onward. In the hippocampus, the embryonic pattern of NTPDase2 expression mirrors that of the dentate migration of neuroblasts. Double‐immunolabeling revealed that NTPDase2 is associated with subpopulations of glial fibrillary acidic protein‐, nestin‐ and doublecortin‐positive radial cells. It is absent from mature granule cells or S100‐positive astrocytes. NTPDase2‐positive cells proliferate. Furthermore, after mitosis, progenitor cells preferentially reveal an NTPDase2‐positive phenotype. Patch‐clamp analysis demonstrates functional nucleotide receptors in progenitor cells expressing nestin promotor‐driven green fluorescent protein. Our results identify the ecto‐nucleotidase NTPDase2 and functional P2X receptors at hippocampal progenitor cells. We infer that signaling pathways via extracellular nucleotides may play a role in the control of hippocampal neurogenesis. © 2005 Wiley‐Liss, Inc.
Alkylthiol gold nanoparticles in sol‐gel‐based open tubular capillary electrochromatography
Authors: Yang Li , Guihen Elizabeth , Glennon Jeremy D. 
Published: May 2005

AbstractA novel open‐tubular capillary electrochromatography (OTCEC) column was prepared by immobilizing dodecanethiol gold nanoparticles on prederivatised fused‐silica capillary columns with sol‐gel technology. 3‐Mercaptopropyl‐trimethoxysilane (MPTMS) was selected as sol‐gel precursor to develop a sol‐gel layer on the inner wall of the capillary, prior to assembly of dodecanethiol gold nanoparticles onto the generated sol‐gel layer through specific interaction between the gold nanoparticles and surface terminating thiol groups. The electrochromatographic behaviour of the sol‐gel gold nanoparticle capillary was compared with a gold nanoparticle capillary prepared via MPTMS surface functionalisation, through variation of the percentage of the organic modifier, pH, and separation voltage. Efficient separation for a “reversed‐phase” test mixture of thiourea, naphthalene, and biphenyl and for selected polycyclic aromatic hydrocarbons (PAHs) was obtained on the sol‐gel based gold nanoparticle capillaries. OTCEC separations of three selected drug substances (propiophenone, benzoin, and warfarin) were also demonstrated. Scanning electron microscopy was used for the characterization of the sol‐gel gold nanoparticle capillary surface. The results confirm that dodecanethiol gold nanoparticles, bound on the sol‐gel‐based inner layer of fused‐silica capillary, can provide sufficient solute‐bonded phase interactions for OTCEC with reproducible retention as well as characteristic reversed‐phase behaviour.
Investigation on the effect of various surface preparations on corrosion performance of powder coated steel by EIS
Authors: Attar M. M. , Naderi R. , Moayed M. H. 
Published: May 2005

AbstractPowder coating systems have been considered for different purposes since they have many advantages in use. The performance of the different powder coating systems needs to be examined by various methods. In this paper, a polyester powder coating was applied on various pretreated mild steel panels. Electrochemical Impedance Spectroscopy (EIS) measurements were used to study the durability of the coating on pretreated mild steels upon immersion in 3.5% w/w NaCl solution at ambient temperature for 7 and 50 days. Various elements of the equivalent circuit are proposed for the different metal/coating systems. The lowest coating and double layer capacitances were measured for acid pickled followed by phosphating pretreated steel panel while the coating and charge transfer resistance were the highest for this system. It revealed an improvement of coating durability on the substrate by phosphating pretreatment. This can be attributed to decreasing ingress of water, dissolved oxygen and ions into the coating.
Korrosionserscheinungen beim Herstellen von Betonfertigteilen in Stahlschalungen
Authors: Meyer D. , Triebert J. , Schulz W.‐D. 
Published: May 2005

AbstractEs wurden Ursachen für die Korrosion an Stahlschalungen bei der Herstellung von Betonfertigbauteilen untersucht, insbesondere der Einfluss von Werkstoffoberfläche (verzundert, geschliffen), Wasser/Zement (W/Z)‐Wert (0,4 bis 0,8), Aushärtetemperatur (Raumtemperatur, 50°C), Chloridgehalt im Beton, Trockendauer (24 h, 72 h) und von Schalöl (niedrig‐hochviskos) ohne und mit Inhibitorzusatz. Es wurde gefunden, dass optimale Bedingungen vorliegen bei mittleren W/Z‐Werten bzw. Einsatz hochviskosen Schalöls. Positiv wirken sich auch Inhibitoren aus, ein Absenken des Chloridgehaltes und der Einsatz verzunderten Materials.
Electrochemical impedance spectroscopy analysis on aluminum alloys in EXCO solution
Authors: Cao F.‐H. , Zhang Z. , Su J.‐X. , Zhang J.‐Q. 
Published: May 2005

AbstractElectrochemical impedance spectroscopy (EIS) of Al‐Zn‐Mg‐Cu alloy in EXCO solution has been investigated. The results show that the impedance spectroscopy of the investigated electrode consists of two capacitive loops in the high and middle frequency domain respectively and an inductive loop in the low frequency domain at the first 30 h of immersion; the inductive arc disappears between 30 h and 60 h while it takes on at the low frequency domain at the last 36 h of the immersion time. A model based on the corrosion mechanism of the aluminum alloy and corroding morphology was proposed and applied to analyze the EIS results.
Evaluation of acupuncture in the treatment of Parkinson's disease: A double‐blind pilot study
Authors: Cristian Adrian , Katz Meredith , Cutrone Eileen , Walker Ruth H. 
Published: May 2005

AbstractAs many as 40% of patients with Parkinson's disease (PD) use some form of complementary medicine during the course of their illness, and many try acupuncture. One nonblinded study of the effects of acupuncture in PD suggested that it might be helpful for some aspects of PD. We performed a double‐blind, randomized, pilot study comparing acupuncture to a control nonacupuncture procedure to determine the effects of acupuncture upon a variety of PD‐associated symptoms. Fourteen patients with Stage II or III PD received acupuncture or a control nonacupuncture protocol. Before and after treatment, patients were evaluated using the Motor subscale of the Unified Parkinson's Disease Rating Scale (UPDRS), the Parkinson's Disease Questionnaire (PDQ‐39), and the Geriatric Depression Scale. There were no statistically significant changes for the outcomes measured. In the patients who received acupuncture, nonsignificant trends toward improvement were noted in the Activities of Daily Living score of the PDQ‐39, the PDQ‐39 Summary Index, and the Motor subscale of the UPDRS. © 2005 Movement Disorder Society
Determination of non‐starch polysaccharides in cereal grains with near‐infared reflectance spectroscopy
Authors: Blakeney Anthony B. , Flinn Peter C. 
Published: May 2005

AbstractCereal grains contain variable amounts of non‐starch polysaccharides, such as arabinoxylans and (1→3),(1→4)‐β‐glucans (β‐glucans), which are associated with their cell walls. The type and composition of these polysaccharides is of increasing interest in both human and animal nutrition. Reference analysis for these polysaccharides requires the use both enzymic and monosaccharide methods. To evaluate fully the non‐starch polysaccharides present in grains, some analysts further distinguish between the soluble and insoluble fractions of these components. Near‐infrared reflectance (NIR) spectroscopy provides fast, inexpensive analysis. It is, however, a comparative technique that relies on multivariate calibration of sample spectra and accurate reference analysis. It has the potential to be exploited as a rapid analytical method for nutritionally important polysaccharides. The calibration statistics for arabinoxylans and β‐glucans obtained in this study suggest that NIR can be used in plant breeding, nutritional and product studies to obtain simple and rapid estimates of non‐starch polysaccharides. The occurrence of wheats with high cell wall contents together with barleys with high β‐glucan contents is well known. However, to date, this genetic variation has not been extensively exploited for the production of grains for use as human food ingredients.
Eomesodermin is expressed in mouse oocytes and pre‐implantation embryos
Authors: McConnell Josie , Petrie Linda , Stennard Fiona , Ryan Kenneth , Nichols Jennifer 
Published: May 2005

AbstractT‐box genes are a highly conserved family of genes encoding transcription factors, which share a conserved DNA binding domain (the T‐box). Appropriate temporal and spatial expression of this gene family is critical for gastrulation and organogenesis in a number of species. The T‐box containing gene Eomesodermin was first identified in Xenopus, where it plays a critical role in mesoderm formation. In situ analyses in mice have described the expression patterns of the mouse ortholog of this gene mEomesodermin (mEomes) at the time of implantation and during fetal development. Additional studies involving the disruption of the mEomes gene, have demonstrated an additional role for mEomes in trophoblast formation. However, these analyses did not address the possibility that maternally encoded or pre‐blastocyst zygotic transcription of mEomes may also contribute to embryonic development. We show here that mEomes mRNA is present prior to blastocyst formation, and that the protein product of mEomes is associated with nuclear DNA during oocyte development and persistently localizes within all nuclei of the preimplantation embryo until the early blastocyst stage. mEomes protein is associated with the meiotic spindle in the unfertilized egg and with the mitotic spindle at each cell division. Our results are consistent with mEomesodermin having a role in early preimplantation development and inner cell mass formation in addition to its function in the trophoblast lineage. Mol. Reprod. Dev. © 2005 Wiley‐Liss, Inc.
Approximating nondominated sets in continuous multiobjective optimization problems
Authors: Martín Jacinto , Bielza Concha , Insua David Ríos 
Published: May 2005

AbstractMany important problems in Operations Research and Statistics require the computation of nondominated (or Pareto or efficient) sets. This task may be currently undertaken efficiently for discrete sets of alternatives or for continuous sets under special and fairly tight structural conditions. Under more general continuous settings, parametric characterisations of the nondominated set, for example through convex combinations of the objective functions or ε‐constrained problems, or discretizations‐based approaches, pose several problems. In this paper, the lack of a general approach to approximate the nondominated set in continuous multiobjective problems is addressed. Our simulation‐based procedure only requires to sample from the set of alternatives and check whether an alternative dominates another. Stopping rules, efficient sampling schemes, and procedures to check for dominance are proposed. A continuous approximation to the nondominated set is obtained by fitting a surface through the points of a discrete approximation, using a local (robust) regression method. Other actions like clustering and projecting points onto the frontier are required in nonconvex feasible regions and nonconnected Pareto sets. In a sense, our method may be seen as an evolutionary algorithm with a variable population size. © 2005 Wiley Periodicals, Inc. Naval Research Logistics, 2005.
Maturation of dendritic architecture: Lessons from insect identified neurons
Authors: Libersat Frederic 
Published: May 2005

AbstractThe highly complex geometry of dendritic trees is crucial for neural signal integration and the proper wiring of neuronal circuits. The morphogenesis of dendritic trees is regulated by innate genetic factors, neuronal activity, and external molecular cues. How each of these factors contributes to dendritic maturation has been addressed in studies of the developing nervous systems of animals ranging from insects to mammals. This article reviews our current knowledge and understanding of the role of afferent input in the establishment of the architecture of mature dendritic trees, using insect neurons as models. With these model systems and using quantitative morphometry, it is possible to define the contributions of intrinsic and extrinsic factors in dendritic morphogenesis of identified neurons and to evaluate the impact of dendritic maturation on the integration of identified neurons into functional circuits subserving identified behaviors. The commonly held view of dendritic morphogenesis is that general structural features result from genetic instructions, whereas fine connectivity details rely mostly on substrate interactions and functional activity. During early dendritic maturation, dendritic growth cone formation produces new branches at all dendritic roots. The second phase is growth cone independent and afferent input dependent, during which branching is limited to high order distal dendrites. During the third phase, activity‐dependent synaptic maturation occurs with limited or subtle remodeling of branching. © 2005 Wiley Periodicals, Inc. J Neurobiol 64: 11–23, 2005
Gonadal hormone modulation of dendrites in the mammalian CNS
Authors: Cooke Bradley M. , Woolley Catherine S. 
Published: May 2005

AbstractThis review focuses on the effect of gonadal steroid hormones, androgen and estrogen, on dendrites in the adult rat central nervous system (CNS). Four hormone‐responsive nuclei are considered: The spinal nucleus of the bulbocavernosus (SNB), the medial nucleus of the amygdala (MeA), the ventromedial nucleus of the hypothalamus (VMN), and the CA1 region of the dorsal hippocampus. Particular emphasis is placed on the mode of hormone action in each nucleus. In the SNB, VMN, and hippocampus, hormones appear to mediate their effects indirectly, via cells other than those that display morphological plasticity. In the MeA, estrogen and/or androgen appears to act primarily on those cells whose dendrites are modulated by the hormone. Importantly, increasing levels of gonadal hormones do not simply result in increases in dendritic parameters. In the VMN, high levels of estrogen associated with proestrus increase dendritic spine density in one subset of cells and reduce spine density in another subset. The pyramidal cells of dorsal CA1 also undergo phasic changes in dendritic spine and synapse density across the estrous cycle. The estrogen‐induced excitatory synapses connect with preexisting axonal boutons that also form synapses with other CA1 cells, thereby increasing the divergence of excitatory afferents to dorsal CA1. These findings indicate that gonadal steroids have a profound impact on the morphology of dendrites and patterns of synaptic connectivity. Consequently, the experimental manipulation of hormone levels is a powerful tool to study structure–function relationships in the mammalian brain. © 2005 Wiley Periodicals, Inc. J Neurobiol 64: 34–46, 2005
Plasticity of dendritic excitability
Authors: Frick Andreas , Johnston Daniel 
Published: May 2005

AbstractDendrites are equipped with a plethora of voltage‐gated ion channels that greatly enrich the computational and storage capacity of neurons. The excitability of dendrites and dendritic function display plasticity under diverse circumstances such as neuromodulation, adaptation, learning and memory, trauma, or disorders. This adaptability arises from alterations in the biophysical properties or the expression levels of voltage‐gated ion channels—induced by the activity of neurotransmitters, neuromodulators, and second‐messenger cascades. In this review we discuss how this plasticity of dendritic excitability could alter information transfer and processing within dendrites, neurons, and neural networks under physiological and pathological conditions. © 2005 Wiley Periodicals, Inc. J Neurobiol 64: 100–115, 2005
Dendritic spine morphogenesis and plasticity
Authors: Lippman Jocelyn , Dunaevsky Anna 
Published: May 2005

AbstractDendritic spines are small protrusions off the dendrite that receive excitatory synaptic input. Spines vary in size, likely correlating with the strength of the synapses they form. In the developing brain, spines show highly dynamic behavior thought to facilitate the formation of new synaptic contacts. Recent studies have illuminated the numerous molecules regulating spine development, many of which converge on the regulation of actin filaments. In addition, interactions with glial cells are emerging as important regulators of spine morphology. In many cases, spine morphogenesis, plasticity, and maintenance also depend on synaptic activity, as shown by recent studies demonstrating changes in spine dynamics and maintenance with altered sensory experience. © 2005 Wiley Periodicals, Inc. J Neurobiol 64: 47–57, 2005