bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Doxycycline Addition on Activated Sludge Microflora and Microbial Communities
Authors: Djelal Hayet , Haddouche Djouza , Lebreton Megane , Barros Vanessa , Villegas Cristian , Dabert Patrick 
Published: February 2024

Municipal wastewater treatment plants (WWTPs) are exposed to high concentrations of micropollutants that can impact conventional activated sludge treatment. The consequences of this include failure to meet discharge standards and the disintegration of flocs, leading to poor sludge settleability. This lab-scale study focuses on the influence of doxycycline, an antibiotic widely used against human and animal diseases, on protozoa, metazoa, and bacterial communities under sludge growing conditions. Doxycycline was added to the mixed liquor of a communal WWTP up to 0, 100, 200, and 400 mg of doxycycline L−1 and incubated in batch conditions for 23 days. The regular addition of nutrient and carbon sources was preformed every 2 days to prevent sludge starvation. Sludge growth, conductivity, and settleability were measured and compared to sludge microbial community structure, determined by microscopic observations and high-throughput 16S rDNA sequencing. The high doxycycline concentration negatively impacted settleability and correlated with a decrease in bacterial diversity and floc disintegration. The addition of doxycycline promoted the enrichment of Proteobacteria Brevundimonas sp., Luteibacter anthropi, and the Bacteroidetes Chryseobacterium massoliae. These species are known to be resistant to a wide spectrum of antibiotics, including tetracyclines. A study of a larger scale may be conducted based on this study’ results.
Carbon monoxide and carboxyhemoglobin contents in exhaled air and blood pressure levels with diff erent nicotine delivery pathways
Authors: Nevzorova V. A. , Stolarova E. A. , Priseko L. G. , Achmetova A. A. 
Published: February 2024

Aim. To assess the content of CO and COHb in exhaled air and the level of blood pressure (BP) in the working-age population of Yuzhno-Sakhalinsk when using various means of nicotine delivery.Materials and methods. The study participants (n = 503) were surveyed using a questionnaire. The BP and oxygen saturation parameters were assessed. The content of CO and COHb content in exhaled air was measured using a smokerlyzer. Statistical processing was performed using nonparametric methods.Results. The study group was dominated by males (58.3%). A high incidence of smoking was observed among females, with up to 42% in the general group and 48.8% in the group of consumers of alternative nicotine delivery systems (ANDS). A correlation between the content of CO and COHb and the smoking experience of more than 10 years was established, regardless of the means of nicotine delivery. Arterial hypertension was registered among 39.8% of the surveyed participants, with a higher frequency in cigarette smokers (28.8%, p = 0.02). This was associated with a greater proportion of individuals (62%) with a long smoking experience of more than 10 years (p = 0.003). A weak direct correlation was established between an increase in blood pressure and the content of CO and COHb (p < 0.001).Conclusion. The share of females as active consumers of tobacco products has grown, particularly in the form of ANDS. Among smokers, the average high level of CO and COHb prevails, which correlates with the smoking experience of more than 10 years and does not depend on the means of nicotine delivery. A direct relationship between the intensity of smoking and the risk of hypertension was established.
Assessment of the respiratory function of patients after COVID-19 pneumonia for medical rehabilitation
Authors: Belyaev A. F. , Fotina O. N. , Kharkovskaya T. S. , Kondrashova N. M. 
Published: February 2024

Aim. To study the indicators of external respiration function in older patients after coronavirus pneumonia (COVID-19) with the purpose of creating personalized rehabilitation programs.Materials and methods. A study of respiratory function after coronavirus pneumonia (COVID-19) was conducted in 109 patients with the average age of 63.7 ± 2.2 (51.3% men and 48.7% women) and the lung damage of more than 25%.Results. The patients after coronavirus pneumonia (COVID-19) show a decrease in respiratory function indicators, such as VC, FVC, FEV1, and SPO2, as well as an increased Tiﬀeneau –Pinelli index.Conclusion. Timely detection of respiratory disorders in patients after COVID-19 pneumonia allows timely diagnosis of respiratory failures and selection of adequate rehabilitation measures.
Health dynamics of children and adolescents in the Far Eastern federal district in 2013–2020
Authors: Gritsina O. P. , Yatsenko A. K. , Trankovskaya L. V. , Maistrovskaya Yu. V. , Ermakova D. A. , Shestakova S. D. 
Published: February 2024

Aim. To identify trends in the primary morbidity of children and adolescents in the Far Eastern Federal District.Materials and methods. A retrospective analytical study of the dynamics of primary morbidity in children and adolescents by disease class was conducted.Results. Among the children population, a very high and high stability of the decrease in morbidity rates was established (R = -0.714– (-1.0)) for all classes of diseases. Among the adolescent population, a weak stability in the decrease in morbidity rates was characteristic of VII Diseases of the eye and adnexa (R = -0.262) and X Respiratory diseases (R = -0.262); a moderate stability of IV Diseases of the endocrine system, nutritional disorders, and metabolic disorders (R = -0.333); a moderate stability of IX Diseases of the circulatory system (R = -0.623); and a high stability among all other classes (R= -0.738 – (-0.928)). In the older age group, weak resistance to growth dynamics was determined in classes III Diseases of the blood, hematopoietic organs, and certain disorders involving the immune mechanism (R = 0.024) and VIII Diseases of the ear and mastoid process (R = 0.095).Conclusion. The data obtained forms a basis for further research into regional risk factors that contribute to poor health of the population. The ﬁndings can also be used to predict the health status of younger generations.
Effect of various pharmacotherapy regimens on the state of carbohydrate metabolism in patients with urination disorders
Authors: Danilov V. V. , Eliseeva E. V. , Danilov V. V. , Volnykh I. Yu. , Tyrtyshnikova A. V. , Piskun M. M. , Danilov V. V. 
Published: February 2024

Aim. To evaluate the eﬃcacy and safety of various pharmacotherapy regimens in patients with urination disorders and type 2 diabetes mellitus during their preparation for surgery.Materials and methods. In total, 130 people (56 men and 74 women) aged from 18 to 81 years (average 65 years) were included in the research. All the patients were on standardized hypoglycemic therapy in combination with alpha1-blockers (doxazosin, terazosin) and vitamin-like drugs (alpha-lipoic acid, levocarnitine). Patients were divided into male and female subgroups, as well as into age subgroups, including under 65 years and over 65 years. Tabular methods of assessing the clinical symptoms of urinary disorders were used, along with instrumental, laboratory, and statistical methods (Mann-Whitney test, Spearman rank correlation coeﬃcient).Results. The duration of therapy averaged 16± 2 months. The observation found that alpha1-blockers lead to a number of positive changes in the composition of carbohydrate metabolism, i.e., the level of serum glucose and insulin. In the general observation group, a signiﬁcant decrease in blood glucose from 6.64 to 6.27 mmol/L, insulin from 18.07 to 14.03 mU/mL, and C-peptide from 3.67 to 2.98 ng/mL was detected. In the male subgroup, glucose levels decreased from 6.45 to 6.00 mmol/L, insulin from 18.92 to 13.99 mU/mL, and C-peptide from 3.76 to 2.97 ng/mL. In the female subgroup, blood glucose levels decreased from 6.98 to 6.77 mmol/L, insulin from 16.41 to 14.1 mU/mL, and C-peptide from 3.51 to 2.99 ng/mL. In the group of patients younger than 65 years of age, a decrease in glucose from 6.22 to 5.93 mmol/L, insulin from 17.87 to 14.36 mU/mL, and C-peptide from 3.49 to 3.01 ng/mL were also observed. In the group of patients older than 65 years of age, similar dynamics of the above parameters was established.Conclusions. The data obtained suggest that alpha1-blockers in combination with vitamin-like drugs contribute to reducing the level of serum glucose, insulin, and C-peptide during a long-term (at least 1 year) therapy, which may be promising in the correction of metabolic disorders during preparation of patients for surgery.
Ultrasound diagnostics in solving situational problems in the discipline of clinical pathophysiology
Authors: Makarov A. B. , Tsygan V. N. , Lemeshchenko A. V. , Rezvantsev M. V. , Krivolutskaya T. A. , Bammatov T. A. 
Published: February 2024

Aim. Тo train future specialists to eﬀectively apply the methods of pathophysiological research (ultrasound diagnostics) in solving situational problems within the course of clinical pathophysiology.Materials and methods. The 2nd and 3rd year students were trained to use stationary and portable ultrasound machines Phillips CX50 and Chison Sonotouch 80. The students were trained to master ultrasound B and M modes, Doppler ultrasonography, as well as elastography of the most common diseases of the endocrine, digestive, and urinary systems. At the ﬁrst stage, students worked in tandem with the lecture, observing the process of sensor manipulation. At the second stage, each student conducted a study on his or her fellow student.Results. When conducting ultrasound scanning of the hepatoduodenal zone and kidneys, 65% and 55% of students, respectively, failed to obtain an optimal image and to measure anatomical structures during the assigned time interval. Echocardioscopy was established to be the most diﬃcult method to master when solving situational problems within the topic of “Impaired Systemic Circulation”. This task was successfully performed only by 20% of the students. The optimal student-lecturer ratio was established to be 6:1.Conclusion. The use of new ultrasound technologies in the training process is important for forming students’ professional competencies and increasing their motivation.
Liver Damage in Campylobacteriosis in Children (Clinical Case)
Authors: Ермоленко К.Д. , Алагова М.В. , Раздьяконова И.В. 
Published: February 2024

В настоящее время кампилобактериоз является одной из наиболее значимых причин бактериальных кишечных инфекций и диарей путешественников в мире. Своевременная диагностика кампилобактериоза и его осложнений является актуальной проблемой и предметом научных исследований. Формирование гепатита при кампилобактериозе, по разным данным, может иметь место у 3–19% детей с кампилобактериозом, выявляется на 1–3-й неделе заболевания и проявляется умеренным повышением уровня сывороточных трансаминаз в 2–3 раза, имеет благоприятное течение. В данной статье описывается клинический случай кампилобактериоза у ребенка 3 лет, осложненного реактивным гепатитом, госпитализированного в ДНКЦИБ. В статье использованы клинико-эпидемиологические, лабораторные данные и сведения из медицинской документации. Опираясь на данные исследований других авторов, рассматриваются наиболее вероятные механизмы поражения печени при кампилобактериозе. На основании данных о высокой распространенности кампилобактериоза и наличия большого количества наблюдений, подтверждающих риски развития острого гепатита при кампилобактериозе, следует отметить необходимость сохранения настороженности у врачей на предмет развития кампилобактерного поражения печени, а также включения маркеров функции печени в обязательный протокол обследования у детей с подтвержденным кампилобактериозом.
Currently, campylobacteriosis is one of the most significant causes of bacterial infections and diarrhea in the world. Timely diagnosis of campylobacteriosis and its results are a pressing problem and serve as the basis for scientific research. The formation of hepatitis in campylobacteriosis, according to various sources, can occur in 3 to 19% of children with campylobacteriosis, manifests itself at 1–3 weeks of the disease and reveals a moderate increase in the level of serum transaminases by 2–3 times, which is favorable for the course. This article describes a clinical case of campylobacteriosis in a 3-year-old child, complicated by reactive hepatitis, hospitalized at the DNA Clinical Hospital. The article uses clinical, epidemiological, laboratory data and information from medical documentation. Based on these studies, other authors conclude about the most likely mechanisms of liver damage in campylobacteriosis. Based on data on the high prevalence of campylobacteriosis and the indication of a large number of observations confirming the risks of developing acute hepatitis with campylobacteriosis, it should be noted the need to maintain alertness among doctors regarding the development of campylobacteriosis of the liver, as well as the inclusion of markers of liver function in the mandatory observation protocol for children with campylobacteriosis.
Persepsi Mahasiswa Program Studi Akuntansi Terhadap Pengetahuan Teknologi Informasi Dan Komunikasi Yang Harus Dikuasai Seorang Akuntan (Studi Kasus Pada Mahasiswa Universitas Muhammadiyah Riau)
Authors: Agmallia Ressy , Sari Muharini Ulya , Ramadhani Annisa Rahima , Afrianti Mutia , Rodiah Siti 
Published: February 2024

This study aims to examine the differences in perceptions of accounting students based on gender and the cumulative predicate index on technology knowledge for accountants. The data in this study were collected using a questionnaire sent to 100 male and female students from a population of 737 students in the 2018 2019 and 2020 accounting study programs. The data used is raw data (primary) obtained through a survey by distributing questionnaires. . The data analysis technique used in this research is normality test, independent sample and One Way Anova. Results of this study indicate that there is no difference in the perception of students in the accounting study program based on gender and the cumulative predicate index on information and communication technology knowledge that accountants must master.Keywords: Gender, Cumulative Predicate Index, Knowledge of Information and Communication Technology
Directive Illocutionary Act In Moana Movie
Authors: Ayu Mas Wiliastini  , Ni Wayan Suastini  , I Wayan Juniartha  
Published: February 2024

Directive is one type of illocutionary act usually used by the speaker to get the hearer to do something. This study discusses the types of directive illocutionary act found in Moana movie and followed by directive illocutionary act. This study used the theory by Kreidler (1998: 189-192) to discuss types of directive illocutionary act and used theory by Leech (1993: 104) to discuss the functions of directive illocutionary act. This study used the documentation method to collect the data and the method used in analyzing data was qualitative. In presenting the finding used formal and informal method. This study found 40 data of directive illocutionary act classified into 11 data or 27% of command, 15 data or 37,5% of request, 14 data or 35% of suggestion and all the data, including the directive function illocutionary act such as; competitive, convivial, collaborative, and conflictive. In the command type there are three functions that found based on the utterance which is collaborative, competitive, and conflictive. For the request type followed by four functions which are, competitive, convivial, collaborative and conflictive. The last type of directive illocutionary act is the suggestion, there are three functions also found in the utterance of Moana movie which is collaborative, convivial, and conflictive.
Types of Flouting Maxim Found In Alice In Wonderland Movie
Authors: Ida Ayu Popy Wulandari Pratiwi  , Ni Made Verayanti Utami  , Ni Nyoman Deni Ariyaningsih  
Published: February 2024

This study entitled The Types of Flouting Maxim found in Alice in Wonderland movie. The study aimed to find out the types of flouting maxim used by characters. This study focused on Grice (1975) about the types of flouting maxim. This study applied the descriptive qualitative method in analyzing the data. To get valid data, this study used note-taking as a technique. The findings showed that there are 4 types of flouting maxim used by the characters. The result of the study showed that the types of flouting maxim found in the movie are 25 data. The dominant flouting maxim uttered by the characters in this movie is the flouting maxim of relevance with the frequency 10 (40%). The findings shows that the most dominant flouting maxim used by the characters is the flouting maxim of relevance because the characters in this movie try to hide the main character's existence by changing the topic in the conversation.
Keywords: flouting maxim, types, movie
Illocutionary Acts in Melati and Isabel Wijsen’s Ted Talk
Authors: Ni Nyoman Indrayani Erlina Saputri , Ni Wayan Suastini  , I Wayan Sidha Karya  
Published: February 2024

With some kind of purpose in mind, the Illocutionary Act learns about the utterance performed. The goal of this study is to resolve the research problems consisting of: (1) What are the types of illocutionary acts found in Ted Talk by Melati and Isabel Wijsen; and (2) What is the role of the illocutionary act used by Ted Talk by Melati and Isabel Wijsen? The data in this analysis were analyzed by Searle (1979) and Leech (1983) respectively, applying the theory of illocutionary forms and functions. 64 statements containing types of illocutionary actions, such as: assertive, directive, commissive and expressive, are shown as the outcome of this study. The most utterances delivered by Melati and Isabel Wijsen in their Ted Talk are assertive, seen in 50 utterances or (78,13 percent). Commissive, directive and expressive are accompanied by the occurrence of eight utterances (12,50 percent), four utterances (6,25 percent), and 2 utterances (3,13 percent). In Melati and Isabel Wijsen's speech, the declarative is not found since the act involves particular circumstances. Moreover, only 3 roles of an illocutionary act were included in the study. It's competitive, fun, and collaborative. Collaborative was the function of illocutionary actions found most in this group.
Keywords: Illocutionary Acts, Melati and Isabel Wijsen, Ted Talk
Function Of Derivational Affixes In Novel The Hobbit
Authors: Alvie Amin Rachmadi  , Ida Bagus Gde Nova Winarta  , I Dewa Ayu Devi Maharani Santika  
Published: February 2024

When the students are able to identify derivational affix, they can develop their vocabulary because from just one word it can gain many words with different part of speech. Novel is a long essay in prose and contains a series of human life stories with others around them with accentuate the character and nature of the actor. In The Hobbit, the story inspired by a children fantasy. From having seeing such phenomenon, the writer found that mastering English is not easy if the students are lack of vocabulary. This research aimed to find out the derivational affixes in in in The Hobbit by J.R.R Tolkien novel. This research is descriptive qualitative research where researcher tries to find out the derivational affix and the roots from the words in The Hobbit by J.R.R Tolkien novel without using statistical calculation. In this research the writer uses all of words that are attached prefix and suffix as the data. The data source is all the chapters which are the beginning of the story, rising the case and the solution in The Hobbit by J.R.R Tolkien novel. The result of analyzing data was gained the derivational affixes that found in in The Hobbit by J.R.R Tolkien novel showed words are 100 (derivational suffixes).Then the roots from the words that also found are 27 (adjective derived from verb), 49 (noun derived from verb), 3 (verb derived from noun) and adverb derived from adjective (21)
Keywords: Function of Derivational Affixes, novel, root, base
Mental health in rock climbing
Authors: Mikutta Christian , Allenbach Eva , Imboden Christian 
Published: February 2024

Introduction
Rock climbing is an increasingly popular sport in the alpine region. It consists of different disciplines such as sport climbing, trad climbing or bouldering. Besides the professionally organized Olympic disciplines of indoor lead/speed climbing and bouldering, there is a large number of athletes who participate in advanced outdoor climbing without professional supervision. Due to this, rock climbing is associated with specific risks and heterogenous attitudes towards risk-taking and management of emotional reactions such as fear. Rock climbing also contains some risk factors for mental health problems, such as the importance of the athlete’s weight and the possibility of traumatic situations.
Methods
We systematically reviewed the current literature using the keywords “rock climbing» and eating disorder, depression, drugs, anxiety disorder, psychosis, bipolar disorder, ADHD, personality traits, and psychology.
Results
From the initial findings, we included 29 papers in the review.
Discussion
We found that rock climbers are at increased risk for eating disorders. Furthermore, there was a surprisingly high number of athletes who practiced the sport while under the influence of drugs. Several models of risk-taking behavior and neurobiological stress reactions are discussed. Finally, rock climbers showed some risk of becoming addicted to the sport.
Conclusion:
There is a lack of evidence regarding the prevalence and risk factors of psychiatric diagnoses in rock climbers. Further research is needed to support these athletes.