bluuebunny/crossref_metadata_2025_split huggingface dataset:
УСТАНОВКА НА ВОЗОБНОВЛЯЕМЫХ ИСТОЧНИКАХ ЭНЕРГИИ ДЛЯ ПОДДЕРЖАНИЯ ПАРАМЕТРОВ МИКРОКЛИМАТА СЕЛЬСКОХОЗЯЙСТВЕННЫХ ОБЪЕКТОВ
Authors: Сыдыков Шурат , Алибек Несипбек , Байболов Асан , Токмолдаев Аманжол , Кәкімбек Исламбек 
Published: October 2023

Из-за изменения климата, в последние годы, среднесуточные температуры атмосферного воздуха значительно повысились в весенние и летние месяцы, и прогнозы указывают на их дальнейшее повышение. При этом, повышение температуры тела животных вызывает изменения на клеточном и системном уровне, которые снижают интенсивность метаболических и производственных процессов, связанных с выделением тепла, в краткосрочной и долгосрочной перспективе (гомеоретическая адаптация). Исселованиями зарубежных ученых доказано, что затраты на охлаждение в летней и отопление зимней периоды года животноводческих помещений, как правило, значительно ниже, чем потери вызываемые множеством негативных последствий с точки зрения физиологических и поведенческих нарушений и значительных потерь в производстве продуктивности молока и перерасхода кормов. Поэтому создание систему, которая обеспечит оптимальные условия для улучшения содержания крупного рогатого скота (КРС) с минимальными энергозатратами в технологических процессах формирования нормативного микроклимата в животноводческих помещениях, является актуальной.
В статье рассматривается вариант формирования микроклимата в животноводческих помещениях в условиях выращивания КРС в малых и средних крестьянских и фермерских хозяйствах республики. Предлагаемая конструкция системы охлаждение и отопления сельскохозяйственных объектов, снижает тепловую мощность и расход электроэнергии на создание нормированного микроклимата в животноводческих помещениях благодаря повышения эффективности применения системы реверсивного теплового насоса чиллера-фэнкойла, интегрированной возобновляемыми источниками энергий, которая обеспечить требуемый технологический эффект минимальными энергозатратами.
PSR J1953+1844 Probably Being the Descendant of an Ultracompact X-Ray Binary
Authors: Yang Z. L. , Han J. L. , Jing W. C. , Su W. Q. 
Published: October 2023

Abstract
PSR J1953+1844 (i.e., M71E) is a millisecond pulsar in a 53 minute binary orbit discovered by the Five-hundred-meter Aperture Spherical radio Telescope. The mass function from pulsar timing is 2.3 × 10−7
M
⊙. The possible redback origin of this system has been discussed by Pan et al. We discuss here an alternative evolution track for this binary system, namely that PSR J1953+1844 is a descendant of an ultracompact X-ray binary (UCXB), which has a hydrogen-poor donor accreting onto a neutron star (NS) with an orbital period of ≤1 hr. We noticed that some UCXB systems hold an accreting millisecond X-ray pulsar (AMXP) and a donor with a mass of about 0.01 M
⊙. M71E has a very similar orbit to those of AMXPs, indicating that it might be evolved from a UCXB similar to PSR J1653–0158. The companion star of M71E should be significantly bloated and it most probably has a carbon and oxygen composition, otherwise a low inclination angle of the orbit is required for a helium companion. The discovery of this M71E binary system may shed light on when and how an NS in a UCXB turns into a radio pulsar.
Fitting Thermal Evolution Models to the Chronological Record of Erg Chech 002 and Modeling the Ejection Conditions of the Meteorite
Authors: Neumann Wladimir , Luther Robert , Trieloff Mario , Reger Philip M. , Bouvier Audrey 
Published: October 2023

Abstract
The history of accretion and differentiation processes in the planetesimals is provided by various groups of meteorites. Sampling different parent body layers, they reveal the circumstances of the metal–silicate segregation and the internal structures of the protoplanets. The ungrouped achondrite Erg Chech 002 (EC 002) added to the suite of samples from primitive igneous crusts. Here we present models that utilize thermochronological data for EC 002 and fit the accretion time and size of its parent body to these data. The U-corrected Pb–Pb pyroxene, Pb–Pb phosphate, and Ar–Ar ages used imply a best-fit planetesimal with a radius of 20–30 km that formed at 0.1 Ma after calcium-aluminum-rich inclusions. Its interior melted early and differentiated by 0.5 Ma, allowing core and mantle formation with a transient lower mantle magma ocean and a melt fraction of <25% at the meteorite layering depth. EC 002 formed from this melt at a depth of 0.8 km in a partially differentiated region covered by an undifferentiated crust. By simulating collisions with impactors of different sizes and velocities, we analyzed the minimum ejection conditions of EC 002 from its original parent body and the surface composition of the impact site. The magma ocean region distinct from the layering depth of EC 002 implies that it was not involved in the EC 002 genesis. Our models estimate closure temperatures for the Al–Mg ages as 1030–1200 K. A fast parent body cooling attributes the late Ar–Ar age to a local reheating by another, late impact.
Écrire, initier et transmettre
Authors: Soler Renaud 
Published: October 2023

La Ḥāfiẓiyya est une confrérie soufie de taille modeste, installée dans le sud du gouvernorat de Giza depuis le xixe siècle. Cette petite confrérie, affiliée à la Ḫalwatiyya, confrérie plus ancienne et aujourd’hui l’une des plus importantes d’Égypte, contribue à l’organisation de la vie religieuse locale par ses pèlerinages et ses rassemblements. La famille de son cheikh fondateur, ʿAbd al-Ḥāfiẓ (m. 1303/1886), dirige toujours la confrérie et a acquis une notabilité locale, au point d’exercer des fonctions politiques et d’arbitrage importantes. Une étude de terrain a permis de montrer l’ancrage d’une mémoire collective dans des pratiques confrériques héritées de l’enseignement du cheikh et ses descendants, se réclamant elles-mêmes de la tradition de la Ḫalwatiyya. Un manuel de soufisme, la Hidāyat al-rāġibīn fī al-sayr wa-l-sulūk ilā malik al-mulūk rabb al-ʿālamīn [La Bonne direction pour ceux qui désirent cheminer vers le Roi des rois Seigneur des mondes], assume ce rôle de transmission écrite ; l’étude de la tradition orale révèle quant à elle le travail de la mémoire et la formation d’une identité confrérique locale et originale.Faire l’histoire de la Ḥāfiẓiyya conduit à évoquer l’histoire sociale des campagnes égyptiennes et à comprendre comment s’articule l’identité locale d’une modeste confrérie de Moyenne-Égypte avec une tradition confrérique plus large et pluriséculaire.
De Her-our à Semnou-Hor
Authors: Ferreres Romain 
Published: October 2023

Sur une des colonnes de la grande salle hypostyle du temple d’Edfou est gravé un rituel où le roi sacrifie un crocodile au dieu Khnoum de Semnou-Hor. Cependant, ce sacrifice apparaît comme déplacé : d’une part, à Edfou, le crocodile est une victime habituelle d’Horus et, d’autre part, Khnoum de Semnou-Hor ne semble pas avoir d’affinité particulière avec les sauriens. Dans cet article, nous proposons d’envisager que si cet étrange mariage est le résultat forcé de la position de cette scène dans la salle hypostyle, il n’en est pas moins un ménage heureux, et ce grâce au concours du syncrétisme.
Immunogenicity Threshold in Allogeneic Cells Impacts CTL Response to Nondominant Congenic Antigens
Authors: Rawat Kavita , Mara Arlind B , King William T , Nnam Chinaza F , Jakubzick Claudia V 
Published: October 2023

Abstract
Transplantation and cancer expose the immune system to neoantigens, including immunogenic (dominant and subdominant) and nonimmunogenic Ags with varying quantities and affinities of immunodominant peptides. Conceptually, immunity is believed to mainly target dominant Ags when subdominant or nondominant Ags are linked within the same cell due to T cell interference. This phenomenon is called immunodominance. However, our previous study in mice showed that linked nonimmunogenic Ags (OVA and GFP) containing immunodominant peptides mount immunity irrespective of the MHC-matched allogeneic cell’s immunogenicity. Consequently, we further explored 1) under what circumstances does the congenic marker CD45.1 provoke immunity in CD45.2 mice, and 2) whether linking two dominant or subdominant Ags can instigate an immune response. Our observations showed that CD45.1 (or CD45.2), when connected to low-immunogenic cell types is presented as an immunogen, which contrasts with its outcome when linked to high-immunogenic cell types. Moreover, we found that both dominant and subdominant Ags are presented as immunogens when linked in environments with lower immunogenic thresholds. These findings challenge the existing perception that immunity is predominantly elicited against dominant Ags when linked to subdominant or nondominant Ags. This study takes a fundamental step toward understanding the nuanced relationship between immunogenic and nonimmunogenic Ags, potentially opening new avenues for comprehending cancer immunoediting and enhancing the conversion of cold tumors with low immunogenicity into responsive hot tumors.
Mycobacterium abscessus Complex-Associated Chronic Meningitis
Authors: Sharma Kusum , Sharma Megha , Shree Ritu , Sehgal Vineet , Sharma Aman , Sharma Navneet , Goyal Manoj , Ray Pallab , Singh Apinderpreet , Modi Manish 
Published: October 2023

Background:

Mycobacterium abscessus complex (MabC) has emerged as an important cause of human infections, including meningitis. In the absence of correct microbiological identification, cases of MabC meningitis are treated with conventional anti-tubercular therapy, thereby worsening the outcome.

Objective:
The current study was conducted to determine the clinical features, antimicrobial susceptibility, and outcome of patients with MabC meningitis.

Material and Methods:
Cerebrospinal fluid specimens processed between 2011 and 2021 were subjected to smear, culture, MALDI TOF identification, hsp65 gene sequencing, and susceptibility testing using Sensititre™ RAPMYCOI plates along with a literature review.

Results:
12 cases of MabC meningitis were identified between 2011 and 2021, 11 of which were M. abscessus subspecies abscessus on hsp65 gene sequencing. A pioneer case of meningitis with M. abscessus subspecies bolletii was also identified. The common predispositions were TB elsewhere, HIV positivity, and head injury. Two patients had dual infections, both MabC and TB. Ten patients succumbed to infection with a mean survival of 11 months. All isolates were susceptible to amikacin and tigecycline and subspecies bolletii had a higher minimum inhibitory concentration (MIC) than subspecies abscessus. A combined analysis with the available literature, reporting 19 more cases, revealed that the overall mortality of MabC meningitis was 61.3% (19/31) and that of shunt-associated/neurosurgical intervention-related MabC meningitis was 66.7% (12/20). To date, out of 20 MabC meningitis isolates in which subspecies identification was carried, 13 were M. abscessus, six were M. massiliense, and one was M. bolletii.

Conclusion:
MabC is an important differential diagnosis of chronic meningitis. Prompt identification and speciation are imperative for targeted therapy, thus improving the overall patient outcome.
Anti-Seizure Monotherapy and Early Abortion Under Real-World Conditions
Authors: Chen Yuanyuan , Wu Junhong , Zhang Hui , Chen Hongnian , Tian Xin , Jing Wei , Wang Xuefeng 
Published: October 2023

Background:
Most pregnant epilepsy patients need to continue using anti-seizure medications (ASMs) to control epileptic seizures.

Objective:
This study aimed to evaluate the risk of early abortion in pregnant epilepsy patients exposed to anti-seizure monotherapy.

Methods and Material:
We prospectively followed up pregnant epilepsy patients treated with anti-seizure monotherapy in our epilepsy center between January 2010 and January 2020 under real-world conditions. Early abortion (spontaneous abortion in the first trimester of pregnancy) was the endpoint.

Results:
Of 211 pregnancies exposed to monotherapy, including 40% (n = 85) to lamotrigine (LTG), 28% (n = 58) to oxcarbazepine (OXC), 15% (n = 32) to sodium valproate (VPA), 9% (n = 19) to levetiracetam, and 8% (n = 17) to carbamazepine, six ended in early abortion. The overall risk of early abortion in pregnant patients exposed to ASM monotherapy was 2.8% (n = 6) [95% confidence interval (CI) = 0.013–0.073]. The risk of early abortion was 2.4% (n = 2) (95% CI = 0.003–0.082) in women treated with LTG, 3.5% (n = 2) (95% CI = 0.004–0.115) in women treated with OXC, and 6.3% (n = 2) (95% CI = 0.008–0.208) in women treated with VPA. The relative risk of early abortion in the LTG, OXC, and VPA groups did not reach statistical significance.

Conclusions:
Although the sample size of our study was small, these results indicate that the use of anti-seizure monotherapy in pregnant epilepsy patients may not increase the risk of early miscarriage. Larger prospective studies are needed for sufficient statistical analysis.
Correlation of Prepontine Cisternal Space Thickness with the Severity of Neurovascular Conflict and its Role in Predicting Outcome of Medical Management in Cases of Trigeminal Neuralgia
Authors: Arora Abhishek J , Kona Kiran K R , Pawar Rajsree , Jyotsna Y 
Published: October 2023

Background:
Trigeminal neuralgia (TN) is a debilitating disorder that presents with sudden onset of severe, unilateral, paroxysmal, and lancinating pain usually lasting for few seconds to few minutes.

Aims and Objectives:
The main aim of our study was to correlate the prepontine cisternal space thickness, with a severity of neurovascular compression (NVC) and percentage reduction of pain (patient outcome).

Materials and Methods:
Ours is an observational prospective study of 40 patients presenting with TN for magnetic resonance imaging in our department. Patients were followed up on medical treatment and their pain severity evaluated on their follow-up visit. Patients were divided into two groups based on prepontine cisternal space (Group A: ≤4 mm, Group B: >4 mm) and into three groups based on the percentage reduction of pain, Group 1 (0–35%), Group 2 (36–70%), and Group 3 consisted of patients with pain reduction of more than 70%. Ipsilateral prepontine cisternal space thickness was correlated with grade of NVC and percentage reduction of pain.

Results:
Mean percentage of pain reduction in group A and group B was 34.12 and 60.68%, respectively. Approximately 23.80% of grade1 NVC were seen in group A and 76.20% in group B, while 80% of grade 3 NVC were seen in group A and only 20% were seen in group B.

Conclusion:
There was poor response to medical treatment, in patients with narrowed prepontine cisternal space thickness with an inverse relationship between the grade of NVC and cisternal space thickness.
Translation of Parkinson's Disease Sleep Scale-2 (PDSS-2) in Hindi (H-PDSS-2) and its Validation for Assessment of Sleep Disturbances among Indian Parkinson's Disease Patients
Authors: Singh Ruchi , Rai Nirendra K. , Chouhan Sunil , Pakhare Abhijit 
Published: October 2023

Background and Objective:
Parkinson's disease sleep scale-2 (PDSS-2) is a reliable sleep assessment tool which has been validated in several languages. As sleep problems have a great impact on the quality of life of Parkinson's disease patients, we aimed to translate and validate PDSS-2 in Hindi for its wider use among Hindi-speaking Indian patients. Our study objective was to translate PDSS-2 in Hindi (H-PDSS-2) and to assess the psychometric properties of H-PDSS-2 questionnaire for its use in Hindi-speaking Indian PD patients. Secondly, we aimed to compare the results with those of the other language PDSS-2 validation studies.

Material and Methods:
This study was done in two phases, enrolling 16 patients and 16 controls in the first/translation phase for assessment of internal consistency and discriminative power of PDSS-2. The test–retest reliability was determined in the second phase on 35 Parkinson's disease patients who were followed-up at an interval of 7–10 days.

Results:
No difficulties were faced by the patients and controls in the first phase, and internal consistency of the scale was good (Cronbach's alpha = 0.804). There was no significant difference in total H-PDSS-2 score at baseline 16.86 ± 10.59 and on retest 16.40 ± 9.54, suggesting good reliability. Intraclass correlation coefficients ranged from 0.710 to 0.901, and precision was 2.82 over the period of 7–10 days. Subdomains of H-PDSS-2 had moderate/high internal validity, and they showed significant correlation with Unified PD Rating Scale (UPDRS) and HY disease scale.

Conclusion:
H-PDSS-2 is equivalent to the original PDSS-2 for tested psychometric attributes. Its use among Indian Parkinson's disease patients will help in the comprehensive assessment of sleep problems among PD patients.
Effects of Serum Cholesterol on Severity of Stroke and Dosage of Statins on Functional Outcome in Acute Ischemic Stroke
Authors: Shridharan Priyanka , Nair Radhika , Gorthi Sankar P , Prakashini K , Chatterjee Aparajita 
Published: October 2023

Background:
A high dose of statin is used to obtain an intensive lipid-lowering in stroke patients, even in patients with normal lipid levels. There are limited data on effect of dosage of statins and functional outcome in stroke patients.

Objectives:

Materials and Methods:
This retrospective observational study was conducted in KMC Hospital Manipal, India between 2016 and 2018.

Result:
A total of 100 consecutive patients were included in the study, out of which 60 (60.0%) were males. Hyperlipidemia was present in 65 (65.0%) patients. On comparing the serum cholesterol levels with infarct volume using MRI, patients with low volume of ≤70 ml had higher mean serum total cholesterol concentration (223.83 mg/dl), whereas patients with high volume of >70 ml had low mean cholesterol level (218.70 mg/dl). The patients were divided into those who received low dose (≤20 mg) versus high dose (≥40 mg equivalent) of Atorvastatin. On comparing the mRS values at baseline and on day 90 with the dose of statins, patients who received a higher dosage had a statistically significant fall in mRS (p-0.045) at day 90.

Conclusion:
It was found that serum cholesterol levels were inversely related to the stroke severity. However, a higher the dose of statins resulted in better functional outcome and survival in post-stroke patients, possibly due to its neuroprotective effect.
Role of Cavernous Sinus Extension and MRI T2 Hypointensity in the Extent of Resection following Trans-Sphenoidal Surgery for Giant Pituitary Adenomas
Authors: Singla Raghav , Sharma Ravi , Suri Ashish 
Published: October 2023

Background:
Giant pituitary adenomas (GPA) pose a significant neurosurgical challenge. In this study, we present an experience of 60 consecutive patients with GPA operated by trans-sphenoidal surgery (microscopic/endoscopic).

Objective:
The aim of this study was to elucidate preoperative factors predicting extent of resection (EOR) following transsphenoidal surgery for GPA.

Materials and Methods:
The study was a retrospective evaluation of 60 adult patients (>18 years) with GPA operated over a decade. The patients were analyzed for their clinical presentation, EOR, radiology, visual outcome, endocrinological outcome, and complications.

Results:
The mean age of the cohort was 41.5 ± 13.3 years, mean tumor volume was 38.2 ± 19.1 cm3, and mean follow-up was 30.6 ± 21.7 months. Improvement in vision was seen in forty patients (66.7%), while another 16 (26.7%) had stable vision as prior to surgery. Duration of visual symptoms was found to be statistically significantly associated with postoperative improvement of vision (P = 0.001). Twenty-four patients (40.0%) underwent subtotal resection (STR), while the remaining 36 patients (60.0%) underwent either gross total or near-total resection. Factors associated with STR were retrosellar (P = 0.04), subfrontal (P = 0.02), Knosp 3,4 cavernous sinus extension (P = 0.03), and MRI T2 hypointensity (P = 0.02). During follow-up, eight patients (13.3%) had radiological evidence of growth of residual tumor.

Conclusions:
Most cases of GPA can be adequately handled by trans-sphenoidal surgery. The presence of retrosellar, subfrontal, cavernous sinus extensions, and T2 hypointensity should alert the surgeon for likelihood of STR, postoperative residual tumor hemorrhage and need for second-stage endonasal or transcranial surgery. However, utilization of extended endoscopic route has allowed good debulking of tumors having subfrontal and parasellar extensions, which was not possible previously using traditional microscopic transsphenoidal surgery.
The RIGHT Scoring System for the Medicolegal Classification of Head Injury
Authors: Gupta Vipin , Singh Hargunbir , Sandhu Mani R. , Kaur Ravinder , Singh Amandeep , Gupta Soumya 
Published: October 2023

Background:
In India, in case of an allegation of assault, the medical officer is required to classify the nature of injury into simple, grievous, and dangerous based upon the Indian Penal Code, which is outdated and has numerous gray areas.

Objective:
The aim of this study is twofold: first, to formulate an objective scoring system for the medicolegal classification of head injuries and Second to validate the proposed scoring system on patients with head injury.

Methods and Material:
A panel of experts consisting of neurosurgeons, radiologists, and forensic specialists came up with an objective scoring system, coined as the RIGHT (radiological-intervention-Glasgow Coma Scale (GCS)-based head trauma) scoring system consisting of three parameters, namely, the motor subscore of the GCS, computerized tomography image findings, and management of the patient. This was used to classify head injuries—into simple, grievous, and dangerous. A single-centre pilot study was planned—including patients with head trauma reporting to the emergency department. Medicolegal nature of the head injury was classified according to the proposed RIGHT score. A 6-month follow-up was performed using the Glasgow Outcome Score (GOS).

Results:
In total, 130 patients with head injury reported to the emergency department. There was a significant correlation between the RIGHT score assigned upon admission and the GOS at 6 months (P < 0.001).

Conclusions:
As the scoring system could be applied objectively and a significant correlation between nature of injury given by RIGHT score and 6-month outcome was present; therefore, the RIGHT scoring system proved to be an effective method in unambiguously classifying the nature of head injury for medicolegal opinions.