bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical significance of serum levels of Saccharomyces cerevisiae IgA, IgG and perinuclear antineutrophil cytoplasmic antibodies in the differential diagnosis of inflammatory bowel diseases
Authors: Stepanov Yu.M. , Stoikevich M.V. , Gaydar Yu.A. , Klenina I.A. , Tatarchuk O.M. 
Published: October 2023

Background. It is important to search for biological markers with high specificity and sensitivity as a non-invasive method for accurate diagnosis of inflammatory bowel disease (IBD), in particular, differentiation of ulcerative colitis (UC) and Crohn’s disease (CD), which is important for both prognosis and treatment. The purpose of the study was to determine the titer of anti-Saccharomyces cerevisiae antibodies (ASCA) IgG, IgA, perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) and their clinical significance in patients with ulcerative colitis and Crohn’s disease. Materials and methods. The study included 49 patients with IBD who were treated at the Department of Intestinal Di­seases of the State Institution “Institute of Gastroenterology of the National Academy of Medical Sciences of Ukraine”. All patients were divided into two groups: 33 individuals with UC and 16 with CD. In addition, the patients were divided into groups depending on the severity of UC course: mild — 3, moderate — 26, and 4 individuals had severe UC. Among patients with CD, severity was moderate in 13 cases and severe CD was detected in 3 cases. p-ANCA IgG were determined by an indirect immunofluorescence assay. The serum level of ASCA IgA and IgG was evaluated by the enzyme-linked immunosorbent assay. The results were statistically processed using the Statistica 6.1 software package. Results. Most patients with UC appeared to have p-ANCA, and in patients with CD, an increased level of ASCA IgA and IgG was found. Among patients with CD, the level of ASCA IgA and IgG depended on the severity of the disease, which was confirmed by the revealed correlation between their level and the severity of the disease (r = 0.608; p = 0.012). Analysis showed that the p-ANCA IgG test for confirming the diagnosis of UC has a sensitivity of 63 % and a specificity of 86 %, whereas the presence of an elevated level of ASCA IgA or IgG for the diagnosis of CD has a sensitivity of 72 % and a specificity of 82 %. The combination of positive p-ANCA IgG and negative ASCA IgA, IgG in patients with UC showed a sensitivity and specificity of 75.6 and 68.8 %, respectively, with a diagnostic accuracy of 68.8 %. For combination of positive ASCA IgA, IgG and negative p-ANCA IgG in patients with CD, the sensitivity was 81.3 % and the specificity was 80 % with a diagnostic accuracy of 80.8 %. Therefore, the simultaneous determination of ASCA IgA, IgG and p-ANCA IgG increases the positive predictive accuracy in the differential diagnosis of UC and CD among patients with IBD. Conclusions. It was found that the separate assessment of ASCA IgA, IgG and p-ANCA IgG for the differentiation of UC and CD has lower sensitivity and specificity, but when the two tests are combined, the predictive value of a positive result and specificity can be significantly increased.
Effect of Sintering Temperature on the Microstructure Behavior of Gelcasted Porous Ceramics Using Cassava Starch as Pore Template
Authors: Putri Suriati Eka , Pratiwi Diana Eka , Tjahjanto Rachmat Triandi , Ilyas Nita Magfirah , Tahir Dahlang , Rahman Abd , Heryanto Heryanto 
Published: October 2023

The gelcasting technique was employed to fabricate porous ceramics utilizing kaolinite clay as the base material with a combination of 20 wt.% cassava starch. The utilization of cassava starch as a pore-template material is a sustainable and eco-friendly approach. The dry mixture compacted pellets underwent calcination for 2 h at three distinct sintering temperatures, namely 900, 1000, and 1100 °C. The present study investigated the impact of sintering temperatures on various ceramic properties, including but not limited to porosity, hardness, crystallinity, lattice strain, and morphology. Furthermore, an increase in sintering temperature led to a reduction in crystallinity of the ceramic material from 81.71 to 78.06%, while the lattice strain increased, as determined by the full width at half maximum peak diffraction calculation. The study determined that the pore size remained microporous (21 Å) across all temperature treatments. Ultimately, a porous ceramic material was fabricated, exhibiting a porosity of 39.44% by volume and a desirable hardness of 94 HB. The optimal sintering temperature for this material was found to be 900 °C. The anticipated application of the porous ceramic, which has taken on a pellet shape, is as a catalyst support for wastewater filtration in the future.
Health Family Indicators in North Lombok Regency
Authors: Fitriadi Yogi , Mahmudah Noor Afif , Muchlis Mumtihana , Danawati Cornelia Wahyu , Istiono Wahyudi , Claramita Mora , Sutomo Adi Heru , Josef Hari Kusnanto 
Published: October 2023

Background: Health family indicators are twelve indicators used to assess family health status. The increase in the health family indicator is one of the parameters of The Indonesia Health Program with a Family Approach (PIS-PK) success. This health family indicator can increase if there is an increase in public awareness of family health and the right policies from the health service or government in an area related to health. To make an appropriate policy, accurate health family indicator survey data is needed that can be used as a guideline to make health-related policies and implement health policies in accordance with problems in the community based on the results of the health family indicator survey, especially for family with vulnerable groups in the context of post disaster/crisis phase. Objectives: This study aims to assess the achievement of health family indicator in North Lombok Regency. This study is the first to be conducted with the aim of describing the health family indicator achievement of families who have family members with vulnerable groups in post disaster/crisis phase. Method: This study is a descriptive study that assesses the health status of families in the North Lombok Regency area. The subject of the study was a family that had family members with vulnerable groups selected by purposive sampling. Data retrieval was conducted by interviewing participants who met the criteria for inclusion and exclusion with the guidance of healthy family indicator questionnaires by trained cadres. The data obtained was analyzed using Microsoft Excel and STATA 16 programs. Result: 292 families in six village met the criteria for inclusion and exclusion. The results of this study showed that 6.51% of family respondents belonged to the category of unhealthy families, 57.53% were pre-healthy families and 35.96% were healthy families. The highest percentage of healthy families is in Santong village (44.93%, n = 69) while the highest percentage of unhealthy families is in Santong Mulia village (19.23%, n = 26). The average percentage of healthy families in six villages is 34.02% while the average percentage of unhealthy families is 8.53%. Conclusion: Most families with vulnerable groups in the North Lombok Regency are pre-healthy families.
Risks to Employees’ Intellectual Property Rights Posed by Artificial Intelligence
Authors: Birštonas Ramūnas 
Published: October 2023

Artificial intelligence (AI) is one of the disruptive technologies, causing new and unforeseen social problems and uncertainty about how these problems should be solved. One such problem area is granting the status of author or inventor to AI in the area of intellectual property protection. One of the risks of giving AI this status is damage to workers’ interests. Currently, employees can benefit from statutory guarantees concerning their creative results. Such existing regulation contributes to ensuring fair remuneration for creative workers and allows them to participate in the commercial success of their creative activities. The development of AI and related regulatory changes may undermine employee guarantees. The article distinguishes and analyses four scenarios – not protecting objects created by AI, granting rights to AI, allocating rights to the employer, or granting them to the employee. The consequences of each choice are evaluated from the point of view of the interests of the employees.
First Century of the Satversme: Constitutional Development and Perspectives
Authors: Balodis Ringolds , Pleps Jānis 
Published: October 2023

The centenary of the Satversme – the Constitution of the Republic of Latvia – in 2022 was an important event for the State of Latvia. The Satversme is one of the oldest valid constitutions in Europe. Its fate is unique, making Latvia interesting in the context of comparative constitutional law.The authors of this article have examined the creation and evolution of the Satversme in the course of the last century, as well as analysed the current changes to the system of the Latvian State. Re-examining the instruments of direct democracy (referendum and legislative initiative), by expanding participation of the totality of Latvia’s citizens in public administration, has been outlined as a direction requiring improvements, likewise, “parliamentary weakness”, leading to judicial activism, is examined and leads to reflections on the need to increase the role of the President in the area of separation of powers, as well as control over the parliament and the executive power.
The Concept of Loyalty in Legal Regulation in the Republic of Latvia: Current Situation and Challenges
Authors: Treļs Ēriks , Mihailovs Ivans Jānis 
Published: October 2023

This publication analyses the concept of loyalty in legal regulation of the Republic of Latvia. The requirement for loyalty is included in several regulatory acts that determine professional standards and requirements for admission to public service or employment. The aim of the paper is to analyse the concept of loyalty in legal regulation and the practice of its application, to identify possible problems, and to propose solutions. The authors have conducted a study using the methods of interpreting the rules of law adopted in legal science. Grammatical, historical, comparative, teleological method and general research methods were used, such as comparison and summarization, causal relationship detection, analysis, and synthesis. Within the framework of the paper, several conclusions are made and proposals are offered for strengthening the requirement of loyalty to the Latvian state in the regulatory framework.
ANALISIS UJI MEKANIK BIOPLASTIK BERBAHAN PATI TEPUNG SAGU- KITOSAN DAN SORBITOL
Authors: Ayu Niken , Jumiati Ety , Husnah Miftahul 
Published: October 2023

Telah dilakukan penelitian pembuatan plastik biodegradable sebagai upaya pncegahan pencemaran sampah plastik pada lingkungan. Penelitian ini bertujuan untuk mengetahui karakterisasi mekanik bioplastik pati tepung sagu dapat dijadikan bioplastik. Penelitian ini menggunakan bahan kitosan, pati tepung sagu dan dengan sorbitol sebesar 50%. Variasi komposisi pati tepung sagu dan kitosan pada sampel A (40% : 60%), B (50% : 50%), dan C (60% : 40%). Pengujian sifat mekanik pada penelitian ini meliputi uji kuat tarik, uji elastisitas (elongasi), dan uji modulus elastisitas. Data hasil pengujian diperoleh nilai kuat tarik 2,7015 MPa, 2,4936 MPa dan 2,3393 MPa dan telah memenuhi ASTM E8-13a, nilai elastisitas diperoleh sebesar 6,6998%, 10,6998%$ dan 11,9220% dan telah memenuhi standar ASTM D882-12, dan nilai modulus elastisitas diperoleh sebesar 0,4032 MPa, 0,2330 MPa dan 0,1962 MPa.
Kata Kunci : Bioplastik, Pati tepung sagu, Kitosan, Plasticizer Sorbitol.
DETEKSI KADAR ETANOL PADA MAKANAN TRADISIONAL LEMANG TAPAI MENGGUNAKAN MIKROBIAL BIOSENSOR
Authors: Hanifah Nadratul , Setiadi Rahmondia Nanda , Yanuar Yanuar , Rosandi Vira Annisa , Umar Lazuardi 
Published: October 2023

Konsumsi etanol memiliki konsekuensi bagi kesehatan, dimana penentuan etanol sangat relevan dengan uji toksikologi klinis yang mempengaruhi sistem saraf, sistem peredaran darah, sistem pencernaan sehingga perlu dideteksi. Biosensor amperometris merupakan alternatif untuk deteksi etanol dalam makanan yang diamati melalui nilai tegangan output, diperoleh dari oksigen terlarut yang tertinggal dari hasil metabolisme sel. Pada penelitian ini dilakukan deteksi etanol secara kuantitatif memanfaatkan biosensor berbasis sel ragi Saccharomyces cerevisiae untuk mengetahui kadar etanol yang terdapat pada makanan tradisional Lemang Tapai dengan nilai <5%. Larutan etanol standar dengan konsentrasi 1.2%, 2.43%, 3.64% dan 4.86% v/v sebagai kalibrasi sensor yang menunjukkan korelasi (r) yang baik yaitu 0.9937. Hasil pengukuran Lemang Tapai yang dideteksi oleh biosensor menunjukkan konsentrasi etanol 2.79%. Pengolahan data konsentrasi yang dihasilkan kemudian diuji menggunakan metode statistik Analysis of Variance (ANOVA) untuk mengetahui signifikansi perbedaan data yang dihasilkan untuk tiap konsentrasi etanol yang diuji. Hasil penelitian ini diharapkan dapat meningkatkan kesadaran dan kewaspadaan masyarakat terhadap adanya etanol dalam makanan tradisional yang berbahaya ketika dikosumsi secara berlebih.
Analysis of Budget Flexibility for the Program of Improving Competence and Professionalism of Madrasah Teachers at the Ministry of Religious Affairs Regional Office for DKI Jakarta Province
Authors: Dian Retno Kencono  , Nurliah Nurdin  , R Luki Kurnia  
Published: October 2023

Refocusing strategy has become one of the fiscal policies adopted by the government when the COVID-19 pandemic hit Indonesia. This strategy involves reallocating the budget from personnel, goods, and capital expenditures to fund the National Economic Recovery Program. However, the implementation of this policy, without adequate preparation, can have performance implications. This research addresses the challenges related to the dynamic and adaptive state budget during a crisis. The method used is a case study based on facts, which is then analyzed using the theory of Budgeting Flexibility, considering three inseparable aspects in achieving budget flexibility: agreement on purposes, mutual commitment between parties, and creating agile organizations. Therefore, Refocusing does not compromise the performance of executing tasks and functions in supporting the implementation of programs aimed at improving the professionalism of teachers in Madrasah education. This research will serve as the basis for policymakers in budget implementation across all levels in the Ministry of Religious Affairs Regional Office for DKI Jakarta Province.
PENGEMBANGAN MODUL BERBASIS DISCOVERY LEARNING DISERTAI NILAI KARAKTER BERBANTU QR CODE PADA MATERI PENCEMARAN LINGKUNGAN UNTUK SISWA KELAS X
Authors: Rosa Mely Diana , Muhfahroyin Muhfahroyin , Asih Triana 
Published: October 2023

The purpose of this development research is to produce a product in the form of a discovery learning-based module with appropriate QR Code-assisted character values ​​so that it can be used by students and increase knowledge. This type of development research using 4D models initiated by Thiagarajan, Sammel and Sammel (1974). This 4D development model has four stages, namely define, design,develop and desseminate, but in development research it only reaches the develop stage. The product that has been developed by this researcher has been validated by design experts, getting a percentage of 93% with the "very good" criteria, material expert validation getting a presentation of 89% with the "very good" criteria, and small group trials getting a percentage of 82% with the "very good" criteria. ". Based on the results of expert validation and small group testing, the product that has been developed in the form of a module is suitable for use by students during the learning process
PENGARUH PENERAPAN LEMBAR KEGIATAN PESERTA DIDIK (LKPD) BERBASIS PENDEKATAN SAINTIFIK TERHADAP HASIL BELAJAR SISWA PADA MATERI SISTEM KOORDINASI KELAS XI DI SMA NEGERI 1 SEKAMPUNG
Authors: Yuliana Eva , Ratini Ratini , Mulyani HRA 
Published: October 2023

The aims of this study was to determine the effect of LKPD based on a scientific approach on cognitive learning outcomes and which one is higher between the average cognitive learning outcomes of the Coordination System Biology using LKPD based on a scientific approach and those without using LKPD. The research method used is a quasi-experimental research method (Quasy Experiment). The experimental design used was the Test-Only control design, namely this design has 2 groups, the first group is the experimental class group and the control class group. The sample in this study was obtained by cluster random sampling, random sampling was obtained by drawing, namely class XI MIPA-1 as the control class and MIPA-2 as the experimental class. The instrument in this study was a test with a total of 17 questions. Based on the research results, it can be seen that the average value of the experimental class is 86.44 and the average value of the control class is 70.88. Based on the results of hypothesis testing using two-party t-test obtained –t1 - < t1 t1 (-2,00< 28,93 > 2,00) means that learning outcomes in the experimental class using LKPD are not the same as learning outcomes in the control class that do not use LKPD. Then based on the hypothesis test using one-party t-test results obtained -tdaf<thit (-1.67 <28.41) means that the learning outcomes of the experimental class using LKPD are greater than the learning outcomes of the control class that do not use LKPD in SMA Negeri 1 Sekampung.
Addressing Water Scarcity in Samdrupjongkhar Thromde, Bhutan: Feasibility Study and Design of a Sustainable Gravity Water Supply System
Authors: Sharma Vasker , Tamang Phurba , Tenzin Rigden Yoezer , Tshering Dawa 
Published: October 2023

Abstract
The provision of a reliable water-supply system is essential for the development and well-being of urban communities. Samdrupjongkhar Thromde, located in Bhutan, has been facing water supply challenges despite the presence of a water treatment plant. The non-perennial nature of the current water source coupled with malfunctions in water pumps has led to acute water shortages in the municipality. To address this issue, this study carried out a feasibility investigation and designed a gravity water supply system by conducting an EPANET (Environment Protection Agency Network Evaluation Tool) analysis. The study involved field visits to identify potential water sources, and a topo-graphic survey using RTK (Real Time Kinematics) technology to determine the optimal pipeline route. The EPANET analysis was then conducted to evaluate the hydraulic performance of the initial route. Based on these findings, a final water pipeline route was selected considering factors such as terrain characteristics, construction feasibility, avoidance of negative water pressure, and minimum encroachment of private land. The results showed that the maximum pressure head within the pipeline system reached 296 m with a maximum water flow velocity of 5 m/s. However, at the outlet, the pressure head decreased to 70 m and the velocity decreased to 2 m/s. Two Break Pressure Tanks (BPT) were strategically placed to achieve this pressure reduction. The chosen pipe materials and their placement ensure the long-term reliability and functionality of the water supply system, while considering maintenance convenience and terrain characteristics.
AS Evaluasi Usability User Interface Website Menggunakan Metode Usability Testing Berbasis ISO 9241-11 (Studi Kasus PT.X)
Authors: Suhendra Agus Ari , Putri Gusti Agung Ayu , Sasmita Gusti Made Arya 
Published: October 2023

Pemanfaatan teknologi informasi dalam dunia bisnis berpotensi besar untuk lebih meningkatkan grafik penjualan, serta meningkatkan efisiensi dan kualitas layanan kepada pelanggan. PT.X adalah salah satu bidang bisnis jual beli barang elektronik yang mengembangkan usahanya dengan membuat website untuk mempermudah proses jual beli produk sejak tahun 2019. Sejak berdirinya website sampai saat ini tidak pernah dilakukan evaluasi mengenai usability sistem yang ada pada website. Penelitian ini bertujuan untuk mengevaluasi dari tingkat usability PT.X dengan metode usability testing berdasarkan dua atribut usability yaitu efektifitas dan efisiensi. Metode yang digunakan yaitu usability testing dengan standard SIO 9241-11 dan teknik Performance Measurement. Adapun pada penelitian ini menggunakan 10 responden untuk menjalani task scenario pada usability testing. Hasil pengujian usability website PT.X mendapat tingkat efektivitas sebanyak 69% dan efisiensi sebanyak 61% dimana nilai tersebut dapat tergolong kedalam status tidak baik dan tidak buruk. Setelah mendapatkan hasil dari usability testing, peneliti membuat rekomendasi perbaikan yang nantinya diharapkan dapat digunakan sebagai acuan untuk dapat meningkatkan tingkat efektivitas dan efisiensi dari website PT.X.
KOLABORASI PERGURUAN TINGGI DENGAN L.S.M UNTUK MEMPERDAYAKAN EKONOMI SECARA HOLISTIK
Authors: - Hermien triyowati , Gunawan Hendra , Yanti Harti Budi , Busnetty Ida , Wahyuningsi Mentari 
Published: October 2023

Pandemi Covid-19 melanda dunia sejak bulan Februari 2020, memunculkan krisis kesehatan dan berbagai kebijakan pengendalian penyebaran pandemi, yang menyebabkan perlambatan pada berbagai sector, dan berujung pada PHK. Situasi ini menyebabkan daya beli menurun, dan berdampak pada turunnya pendapatan masyarakat. Khususnya terhadap UMKM di pasar tradisional, kondisi ini berdampak pada turunnya omset penjualan pedagang rata-rata 40% (Gorgeu, R.; Ibrahim, AM; Antara, et.al.; Dinda, W., 2020). Selain itu, Saadatuddaraen (2021), memberikan bukti, bahwa, adanya PHK di kota Tangerang Selatan, menyebabkan bertambahnya jumlah pengangguran menjadi 84.000 orang dari total 1.7 juta penduduk. Berdasarkan fakta ini, FEB Usakti, bermaksud menyelanggarakan kegiatan Pengabdian kepada Masyarakat (PkM), bertujuan untuk membantu mencari solusi berbagai permasalahan UMKM dimasa Pandemic Covid-19. Kegiatan ini adalah untuk memberikan pemberdayaan terhadap UMKM, dalam legalisasi usaha, permodalan usaha dan digitalisasi usaha. Permodalan Usaha terkait dengan pemulihan usaha karena UMKM bangkrut, yang salah satu syaratnya adalah Legalisasi Usaha. Sedangkan digitalisasi usaha terkait dengan aktvitas usaha (keuangan maupun pemasaran) secara online.
Kegiatan PkM ini bermitra dan berkolaborasi dengan beberapa Lembaga Swadaya Masyarakat, yaitu Wiranesia Foundation, menaungi komunitas UMKM, tersebar diseluruh kabupaten/kota propinsi di Indonesia; FACTA (Forum Anak Cileduk Tangerang), menaungi komunitas UMKM di Cileduk - Tangerang Kota dan komunitas UMKM di pasar Tradisional Ceger, Tangerang Selatan. Kegiatan ini dilakukan secara daring melalui Webinar, dengan metode pelatihan, penyuluhan dan pendampingan manajemen. Hasil kegiatan PkM, menemukan beberapa fakta seperti: kebutuhan UMKM atas pengembangan kualitas teknologi digital SDM, untuk pemasaran produk dan atau transaksi dengan perbankan dalam hal pembiayaan inclusive secara online; pentingnya legalisasi usaha dan sejauh mana tanggapan dan antusiasme UMKM memperoleh bimbingan dan pembinaan usahanya. Beberapa implikasi kegiatan ini, adalah dalam rangka menjadikan pelaksanaan PkM FEB Usakti lebih berkualitas, effektif, effisien dan tercapainya tujuan PkM itu sendiri.