bluuebunny/crossref_metadata_2025_split huggingface dataset:
Brands as drivers of social media fatigue and its effects on users’ disengagement: the perspective of young consumers
Authors: Fernandes Teresa , Oliveira Rodrigo 
Published: February 2024

Purpose
Social media has become an inescapable part of our lives. However, recent research suggests that excessive use of social media may lead to fatigue and users’ disengagement. This study aims to examine which brand-related factors contribute to social media fatigue (SMF) and its subsequent role on driving lurking behaviors, particularly among young consumers.

Design/methodology/approach
Based on survey data from 282 young users of social media, a holistic model of brand-related drivers and outcomes of SMF was tested, emphasizing the contribution of brands’ social media presence to users’ disengagement.

Findings
Research shows that branded content overload and irrelevance, as well as branded ads intrusiveness significantly impact SMF, which in turn plays a mediating role between brand-related drivers and lurking behaviors. The authors further conclude that the impact of SMF on lurking is stronger for users who follow a larger set of brands.

Originality/value
The study contributes to social media research by addressing its “dark side” and empirically validating the role of brands’ social media presence in developing young users’ fatigue and disengagement. The study further adds to the scant literature on SMF, which was mostly developed outside the branding field. Research also provides valuable insights to brands on how to improve their social media performance.
Social experiences of deaf and hard‐of‐hearing students at a Saudi Arabian university: A qualitative study
Authors: Alsamih Munirah 
Published: February 2024

AbstractThis study explored the social experiences of 12 deaf and hard‐of‐hearing female university students. Semi‐structured interviews identified four key themes: university environment, peer interactions, communication and personal barriers. The majority of participants described their social experiences as positive and better than their experiences at school. The participants experienced collaboration, support, peer acceptance, friendship and high awareness of hearing disability among their hearing peers. Communication with peers was facilitated by using applications, sign language and lip reading. However, a lack of understanding from faculty members, isolation, and ignorance exhibited by some peers resulted in negative experiences for a few participants. Some participants reported personal barriers, such as personal characteristics, past negative experiences, and fear of disclosing their disability. Given the importance of social support and inclusion for students' success and well‐being, universities must prioritise the social experiences of deaf and hard‐of‐hearing students as much as their academic experiences.
Tracking long‐term services and supports rebalancing through workforce data
Authors: Ne'eman Ari 
Published: February 2024

AbstractObjectiveTo understand trends in the long‐term services and supports (LTSS) workforce and assess workforce data as a measure of progress in shifting LTSS resources from institutional to community‐based settings.Data Sources/Study SettingWorkforce data from the American Community Survey from 2008 to 2022.Study DesignMeasures of LTSS rebalancing and institutional and community workforce supply per 1000 persons with LTSS needs were constructed. After showing national trends over the study period, state fixed effects regressions were used to evaluate the within‐state relationship of these measures with existing measures of LTSS utilization. Workforce supply measures were compared to the percentage of state Medicaid LTSS spending spent in the community to assess their utility for across state comparisons. Each state's progress in LTSS rebalancing over the study period was then shown using workforce data.Data Collection/Extraction MethodsA sample of 336,316 LTSS workers and 3,015,284 people with LTSS needs over the study period was derived from American Community Survey data.Principal FindingsFrom 2008 to 2022, the percentage of the LTSS workforce employed in the community rose from 44% to 58%. Thirty states saw more than a 10 percentage point increase. From 2008 to 2013, the size of the community workforce expanded dramatically but has since stagnated. In contrast, the institutional workforce entered a long‐term decline beginning in 2015 that accelerated during the COVID‐19 pandemic. State fixed effects regressions showed that measures of workforce supply have a strong relationship with LTSS utilization measures for older adults, but not for younger people with disabilities.ConclusionsWorkforce data can serve as an effective measure of changes in LTSS utilization for older adults. This offers researchers and policymakers a useful alternative to administrative claims, bypassing threats to comparability from coding changes and the shift to managed care. Additional data is needed on workforce trends in services for younger LTSS consumers.
Changes in antibody titer after four and five doses of the SARS‐CoV‐2 vaccine in Japanese post‐kidney transplant patients
Authors: Fujieda Kumiko , Tanaka Akihito , Kikuchi Ryosuke , Takai Nami , Saito Shoji , Yasuda Yoshinari , Sano Yuta , Kato Masashi , Furuhashi Kazuhiro , Maruyama Shoichi 
Published: February 2024

AbstractIntroductionImmunosuppressed patients exhibit low antibody acquisition rates following severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) vaccination. Kidney transplant recipients previously exhibited low antibody acquisition rates after two vaccine doses, which increased after the third dose. We evaluated antibody titers of Japanese post‐kidney transplant patients after the fourth and fifth vaccinations.MethodsAntibody titers for SARS‐CoV‐2 spike protein were measured between 3 weeks and 3 months after the fourth or fifth vaccination.ResultsIncreased antibody acquisition rates were observed after the fourth (75.0% antibody‐positive) and fifth (81.5% antibody‐positive) vaccinations. The antibody‐acquired group after the fourth vaccination exhibited a higher body mass index and estimated glomerular filtration rate (eGFR) than the non‐acquired group. A higher eGFR was associated with antibody acquisition after the fifth vaccination.ConclusionIn Japanese post‐kidney transplant patients, the antibody acquisition rate increased with each vaccine additional dose. Additional vaccinations are recommended to protect against SARS‐CoV‐2 infection.
Sex differences in neuromuscular and biological determinants of isometric maximal force
Authors: Giuriato Gaia , Romanelli Maria Grazia , Bartolini Desirée , Vernillo Gianluca , Pedrinolla Anna , Moro Tatiana , Franchi Martino , Locatelli Elena , Andani Mehran Emadi , Laginestra Fabio Giuseppe , Barbi Chiara , Aloisi Gloria Fiorini , Cavedon Valentina , Milanese Chiara , Orlandi Elisa , De Simone Tonia , Fochi Stefania , Patuzzo Cristina , Malerba Giovanni , Fabene Paolo , Donadelli Massimo , Stabile Anna Maria , Pistilli Alessandra , Rende Mario , Galli Francesco , Schena Federico , Venturelli Massimo 
Published: February 2024

AbstractAimForce expression is characterized by an interplay of biological and molecular determinants that are expected to differentiate males and females in terms of maximal performance. These include muscle characteristics (muscle size, fiber type, contractility), neuromuscular regulation (central and peripheral factors of force expression), and individual genetic factors (miRNAs and gene/protein expression). This research aims to comprehensively assess these physiological variables and their role as determinants of maximal force difference between sexes.MethodsExperimental evaluations include neuromuscular components of isometric contraction, intrinsic muscle characteristics (proteins and fiber type), and some biomarkers associated with muscle function (circulating miRNAs and gut microbiome) in 12 young and healthy males and 12 females.ResultsMale strength superiority appears to stem primarily from muscle size while muscle fiber‐type distribution plays a crucial role in contractile properties. Moderate‐to‐strong pooled correlations between these muscle parameters were established with specific circulating miRNAs, as well as muscle and plasma proteins.ConclusionMuscle size is crucial in explaining the differences in maximal voluntary isometric force generation between males and females with similar fiber type distribution. Potential physiological mechanisms are seen from associations between maximal force, skeletal muscle contractile properties, and biological markers.
Treating the innocent victims of trolleys and war
Authors: Gross Michael L. 
Published: February 2024

AbstractBoth trolleys and war leave innocent victims to suffer death and injury. Trolley problems accounting for the injured, and not only the dead, tease out intuitions about liability that enhance our understanding of the obligation to provide compensation and medical care to civilian victims of war. Like many trolley victims, civilians in war may suffer justifiable, excusable, or negligent harms that demand compensation. Chief among these is collateral harm befalling civilians. Collateral harm is endemic to war and comprises permissible but unavoidable death or injury following necessary and proportionate military operations. Although state armies sometimes offer condolence payments for civilian death, injury, and property loss, they deny liability. Instead, they use compensation to enhance counterinsurgency efforts and assuage feelings of agent regret. As part of the medical rules of eligibility, Coalition forces in Iraq and Afghanistan also provided medical care to victims of collateral harm. However, they denied care to similarly sick or injured civilians. While compensation is often justified to cure the harm civilians suffer, the differential use of medical resources is not. Rather, medical care remains subject to the principle of beneficence and medical need. The duty to provide civilian healthcare in war, particularly in wars of humanitarian intervention, is far‐reaching and imposes significant costs that military and medical ethics are yet to recognize.
Seeing myself through the eyes of my peers: Explaining the self‐concept of students with and without special educational needs through acceptance and friendship
Authors: Douma Ivonne , de Boer Anke , Minnaert Alexander 
Published: February 2024

AbstractIntroductionPaving the way towards inclusive education, it is essential to aim for positive social outcomes for all students, including cultivating a positive self‐concept and fostering acceptance and friendships with peers. Although self‐concept, acceptance and friendships are interrelated, research focussing on the relationship between these constructs remains limited.MethodThis study examined the self‐concept, acceptance and friendships of two groups of typically developing students in secondary education (n = 401) and two groups of students in special secondary education with either an intellectual disability (ID) (n = 58) or social, emotional and behavioural difficulties (SEBD) (n = 68).ResultsLower self‐concept scores were found for students with ID on some dimensions, whereas typically developing students reported lower acceptance and friendship scores. Multilevel analyses indicated that acceptance is a predictor for several different dimensions of self‐concept in the different groups of students, but friendship is less likely to predict self‐concept scores.DiscussionThe results of the study emphasize the importance of promoting peer acceptance amongst all students in inclusive school settings in order to realize the intended positive social outcomes of inclusive education.
Refining the 9q34.3 microduplication syndrome reveals mild neurodevelopmental features associated with a distinct global DNA methylation profile
Authors: Rots Dmitrijs , Rooney Kathleen , Relator Raissa , Kerkhof Jennifer , McConkey Haley , Pfundt Rolph , Marcelis Carlo , Willemsen Marjolein H. , van Hagen Johanna M. , Zwijnenburg Petra , Alders Marielle , Õunap Katrin , Reimand Tiia , Fjodorova Olga , Berland Siren , Liahjell Eva Benedicte , Bojovic Ognjen , Kriek Marjolein , Ruivenkamp Claudia , Bonati Maria Teresa , Brunner Han G. , Vissers Lisenka E. L. M. , Sadikovic Bekim , Kleefstra Tjitske 
Published: February 2024

AbstractPrecise regulation of gene expression is important for correct neurodevelopment. 9q34.3 deletions affecting the EHMT1 gene result in a syndromic neurodevelopmental disorder named Kleefstra syndrome. In contrast, duplications of the 9q34.3 locus encompassing EHMT1 have been suggested to cause developmental disorders, but only limited information has been available. We have identified 15 individuals from 10 unrelated families, with 9q34.3 duplications <1.5 Mb in size, encompassing EHMT1 entirely. Clinical features included mild developmental delay, mild intellectual disability or learning problems, autism spectrum disorder, and behavior problems. The individuals did not consistently display dysmorphic features, congenital anomalies, or growth abnormalities. DNA methylation analysis revealed a weak DNAm profile for the cases with 9q34.3 duplication encompassing EHMT1, which could segregate the majority of the affected cases from controls. This study shows that individuals with 9q34.3 duplications including EHMT1 gene present with mild non‐syndromic neurodevelopmental disorders and DNA methylation changes different from Kleefstra syndrome.
Effect of the NFIB rs28379954 T>C polymorphism on CYP2D6‐catalyzed metabolism of solanidine
Authors: Smith Robert Løvsletten , Wollmann Birgit M. , Størset Elisabet , Lenk Hasan Çağın , O'Connell Kevin S. , Kristiansen Marianne Kringen , Ingelman‐Sundberg Magnus , Molden Espen 
Published: February 2024

AbstractCytochrome P450 2D6 (CYP2D6) is important for metabolism of 20%–25% of all clinically used drugs. Many known genetic variants contribute to the large interindividual variability in CYP2D6 metabolism, but much is still unexplained. We recently described that nuclear factor 1B (NFIB) regulates hepatic CYP2D6 expression with the minor allele of NFIB rs28379954 T>C significantly increasing CYP2D6‐mediated risperidone metabolism. In this study, we investigated the effect of NFIB T>C on metabolism of solanidine, a dietary CYP2D6 substrate. Analyses of solanidine and metabolites (M414, M416, and M444) were performed by ultra‐high performance liquid chromatography‐high‐resolution mass spectrometry in a cohort of 463 CYP2D6‐genotyped patients of which with 58 (12.5%) carried NFIB TC (n = 56) or CC (n = 2). Increased metabolism of solanidine was found in CYP2D6 normal metabolizers (NMs; n = 258, 55.7%) carrying the NFIB C variant (n = 27, 5.8%) with 2.83‐ and 3.38‐fold higher M416‐to‐solanidine (p = 0.039) and M444‐to‐solanidine (p = 0.046) ratios, respectively, whereas this effect was not significant among intermediate metabolizers (n = 166, 35.9%) (p ≥ 0.09). Importantly, no effect of the NFIB polymorphism on solanidine metabolism was seen in TC or CC carriers lacking CYP2D6 activity (poor metabolizers, n = 30, 6.5%, p ≥ 0.74). Furthermore, the NFIB polymorphism significantly explained variability in solanidine metabolism (M414 p = 0.013, M416 p = 0.020, and M416 and M444 p = 0.009) in multiple linear regression models for each metabolic ratio in the entire population, correcting for covariates (including CYP2D6 genotypes). Thus, the study confirms the effect of NFIB in regulating CYP2D6 activity, suggesting an about 200% increase in CYP2D6‐mediated clearance in NMs being NFIB CT or CC carriers, comprising around 6% of Europeans.
Geopolymers made using organic bases. Part I: Synthesis and atomic structure
Authors: Samuel Devon , Kriven Waltraud M. 
Published: February 2024

AbstractGeopolymers can act as a facile forming route to aluminosilicate ceramic composites due to being processed as fluids rather than as powders. However, the compositions available via typical alkali geopolymers are limited by the presence of alkali cations, introduced by the alkali silicate solution precursors. In order to expand the ceramic compositions that are accessible by geopolymer processing, this study explored the use of three strong organic bases (guanidine, tetramethylguanidine [TMG], and tetramethylammonium hydroxide [TMAOH]) as alternatives to inorganic alkali hydroxides in geopolymer synthesis. Silicate solutions were able to be produced with all three bases and favorable silica speciation was identified in the guanidine and TMG silicate solutions. Monolithic bodies were produced using guanidine and TMAOH, while no TMG samples hardened. By 27Al and 29Si nuclear magnetic resonance spectroscopy and powder X‐ray diffraction, the guanidine samples were determined to be structurally similar to those made using sodium hydroxide and hence can be called geopolymers, while the solids made with TMAOH were not structurally similar to sodium geopolymers and contained one or more unknown phases. This study has demonstrated that geopolymers can be made using organic bases rather than alkali hydroxides and that the speciation of dissolved silica alone does not indicate that an organic base silicate solution will be reactive.
Insider versus outsider workplace mistreatment and their impact on affective ill‐being in healthcare professionals: Can personal resources act as buffers?
Authors: Yaranon Paolo , O'Shea Deirdre , Bosak Janine , Sommovigo Valentina 
Published: February 2024

AbstractAimsWorkplace stress can negatively impact healthcare providers' professionalism and quality of care. One source of workplace stress is the experience of workplace mistreatment. Drawing on the Job Demands‐Resources theory, this study aimed to (a) investigate the impact of mistreatment frequency experienced by healthcare workers from insider sources (i.e. co‐workers, supervisors) and outsider sources (i.e. patients, visitors) on affective ill‐being and (b) the potential moderating role of trait resilience and trait self‐efficacy, as personal resources, in the mistreatment–ill‐being relationship.DesignLagged design.MethodsWe collected data from 153 Irish healthcare workers between January 2018 and June 2019 via three surveys, separated by 1‐week intervals. Personal resources were measured at Time 1, frequency of mistreatment from the two sources was assessed at Time 2 and affective ill‐being was assessed at Time 3. We used moderated regression analyses to evaluate the association of mistreatment frequency from the two sources and affective ill‐being and the moderating effect of personal resources.ResultsOnly insider mistreatment frequency was positively related to affective ill‐being. Furthermore, the positive impact of insider mistreatment on affective ill‐being was moderated by self‐efficacy (but not by trait resilience). In contrast to our expectations, the relationship was stronger at high levels compared to low levels of self‐efficacy.ConclusionMistreatment from co‐workers and supervisors is linked to higher levels of affective ill‐being. Additionally, healthcare workers with high self‐efficacy were more vulnerable to the negative consequences of co‐worker and supervisor mistreatment as it impacted their affective ill‐being.ImpactThese findings extend the literature on workplace mistreatment by integrating insider and outsider perpetrators of mistreatment and examining their differential impact on the employees' affective ill‐being. It also highlights mistreatment from organizational insiders as a significant factor in the relationship between mistreatment and affective ill‐being.Patient or Public ContributionNo patient or public contribution.What Does this Paper Contribute to the Wider Global Community?

The findings underscore the detrimental impact of workplace mistreatment on the well‐being of healthcare professionals.

The study findings of higher frequency of insider mistreatment being associated with increased affective ill‐being call for action, with line managers and supervisors being critical to achieving respective changes in healthcare workers' environment.

The findings have implications for policymakers interested in developing a framework to support healthcare professionals in addressing workplace mistreatment, enabling them to effectively fulfil their role as care providers.
Understanding African American help‐seeking for romantic relationships: Advocacy, barriers, and considerations
Authors: Hubbard Aimee , Harris Steven , Dick Mary , McGee DasJohn 
Published: February 2024

AbstractAfrican American couples experience greater levels of relationship distress than other racial/ethnic groups, but they are less likely to seek formal couple counseling. Existing literature highlights the importance of community support in the form of church, family, and friends. While the literature suggests that African Americans encounter unique barriers, we do not know how racism and discrimination impact the couple help‐seeking process. This study seeks to address this gap and better understand unique barriers in the African American couple help‐seeking (AACHS) process via a grounded theory‐informed qualitative study. Findings from interviews with 11 African American individuals in committed relationships highlighted mistrust as a significant barrier to AACHS, while community supports are frequently sought out. Our findings add to current understandings about AACHS and highlight important areas for future research. In the clinical implications section, the authors outline tangible steps that clinicians can take based on the findings from this study.
For love and money: Navigating values at the antiques roadshow event
Authors: Cornish Helen , Weston Gavin , Djohari Natalie , Urdea Alexandra , Liber Elena , Evans Lowri 
Published: February 2024

AbstractAntiques Roadshow Events are held in historic locations across the United Kingdom. On site, experts evaluate objects brought in by attendees, who are often cast as passive recipients, while edited highlights make up the long‐running BBC TV program. Through Collaborative Event Ethnography at one Roadshow Event we show how object stories are navigated through “value talk” between attendees and experts in front of live audiences. Value is not a measurement but a dimension of the thing and its context. Stories and money are both integral in understanding worth, and final valuations are only partially shaped by given expertise.