bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of Mesoporous Silica Nanoparticles from a Low-concentration CnTMAX–Sodium Silicate Components
Authors: Lin Hong-Ping , Tsai Chih-Pin 
Published: October 2003

Abstract
The 30–100 nm primary particles of mesoporous silica have been conveniently synthesized from a highly dilute aqueous solution of CnTAMX–sodium silicate.
Effect of glial cell line‐derived neurotrophic factor (GDNF) co‐transplantation with fetal ventral mesencephalic cells (VMC) on functional restoration in 6‐hydroxydopamine (6‐OHDA) lesioned rat model of Parkinson's disease: neurobehavioral, neurochemical and immunohistochemical studies
Authors: Chaturvedi R.K. , Agrawal A.K. , Seth K. , Shukla S. , Chauhan S. , Shukla Y. , Sinha C. , Seth P.K. 
Published: November 2003

AbstractAmong trophic factors already known, glial cell line‐derived neurotrophic factor (GDNF) and other members of its family have potent and specific action on dopaminergic neurons. In the present investigation an attempt has been made to validate the role of GDNF co‐transplantation with fetal ventral mesencephalic cells (VMC) on functional viability and restoration using neurobehavioral, neurochemical and immunohistochemical parameters at 6 weeks post‐transplantation in 6‐hydroxydopamine (6‐OHDA) lesioned rat model of Parkinson's disease (PD). A significant restoration (P<0.01) in d‐amphetamine induced rotations, spontaneous and apomorphine induced locomotor activity in rats co‐transplanted with VMC and GDNF was observed as compared to VMC alone transplanted rats. Level of dopamine (DA), 3,4‐dihydroxy‐phenyl acetic acid (DOPAC) and dopamine D2 (DA‐D2) receptors in the caudate putamen (CPu) were significantly (P<0.001) restored in co‐transplanted group as compared to VMC transplanted or GDNF administered animals. The functional viability of transplanted VMC was confirmed by tyrosine hydroxylase (TH) expression and quantification of TH‐positive cells by image analysis revealed a significant restoration in TH‐IR fibers density as well as TH‐IR neurons counts in co‐transplanted animals over VMC transplanted animals. Results suggest that co‐transplantation of VMC and GDNF may be a better approach towards functional restoration in 6‐OHDA lesioned rat model of Parkinson's disease.
HPV prevalence among partners of women with cervical intraepithelial neoplasia
Authors: Rosenblatt C. , Lucon A.M. , Pereyra E.A.G. , Pinotti J.A. , Arap S. , Ruiz C.A. 
Published: November 2003

AbstractObjectives: The objective of this study was to find HPV DNA incidence in women with CIN and normal women and in their respective partners, as well as the relation between the virus groups found in women with CIN or normal women and in their respective partners. Methods: Partners of 30 women with CIN at several grades and of 60 normal women were prospectively assessed. In men, HPV search was performed by collecting samples through penile scraping for Hybrid Capture, followed by peniscopic evaluation and biopsy of acetowhite lesions. Results: The presence of HPV DNA in male partners does not necessarily implicate the presence of HPV or even CIN in their female partners. Conclusions: If these results are confirmed by other authors, obtaining a peniscopy, a penile biopsy, and a HPV DNA search in partners that present with no clinical lesions, but in couples with women having CIN, would not be warranted.
Pregnancy outcomes in foreign‐born and US‐born women
Authors: Forna F. , Jamieson D.J. , Sanders D. , Lindsay M.K. 
Published: November 2003

AbstractObjectives: To compare pregnancy outcomes between foreign‐born women and women born in the United States (US‐born). Methods: A retrospective cohort study (1991–2001) of all deliveries at Grady Memorial Hospital in Atlanta, Georgia. Results: Among 49 904 deliveries, 27% were to foreign‐born mothers representing 164 countries grouped into eight geographic regions. Compared with US‐born women, foreign‐born women had a higher mean birthweight (3315 vs. 3083 g), and a lower risk of preterm delivery (RR 0.46, 95% CI 0.43–0.49), perinatal mortality (RR 0.40, 95% CI 0.36–0.45), hypertension (RR 0.31, 95% CI 0.23–0.41), and HIV infection (RR 0.13, 95%CI 0.10–0.18). However, foreign‐born women had an increased risk of diabetes (RR 1.63, 95% CI 1.48–1.79), perineal laceration (RR 1.71; 95% CI 1.66–1.76), and postpartum hemorrhage (RR 1.10; 95% CI 1.05–1.15). Conclusions: Foreign‐born women have better health behaviors, pregnancy outcomes, and a lower risk of infectious diseases than US‐born women, but they have a higher risk of certain medical conditions and obstetric complications.
Hyperthyroidism modifies ecto‐nucleotidase activities in synaptosomes from hippocampus and cerebral cortex of rats in different phases of development
Authors: Bruno Alessandra Nejar , Da Silva Rosane Souza , Bonan Carla Denise , Battastini Ana Maria Oliveira , Barreto‐chaves Maria Luiza M. , Sarkis João José Freitas 
Published: November 2003

AbstractHere we investigate the possible effects of the hyperthyroidism on the hydrolysis of the ATP to adenosine in the synaptosomes of hippocampus, cerebral cortex and blood serum of rats in different developmental phases. Manifestations of hyperthyroidism include anxiety, nervousness, tachycardia, physical hyperactivity and weight loss amongst others. The thyroid hormones modulate a number of physiological functions in central nervous system, including development, function, expression of adenosine A1 receptors and transport of neuromodulator adenosine. Thus, hyperthyroidism was induced in male Wistar rats (5‐, 60‐, 150‐ and 330‐day old) by daily injections of l‐thyroxine (T4) for 14 days. Nucleotide hydrolysis was decreased by about 14–52% in both hippocampus and cerebral cortex in 5 to 60‐day‐old rats. These changes were also observed in rat blood serum. In addition, in 11‐month‐old rats, inhibition of ADP and AMP hydrolysis persisted in the hippocampus, whereas, in cerebral cortex, an increase in AMP hydrolysis was detected. Thus, hyperthyroidism affects the extracellular nucleotides balance and adenosine production, interfering in neurotransmitter release, development and others physiological processes in different systems.
Analysis of two sling procedures using polypropylene mesh for treatment of stress urinary incontinence
Authors: Hung M.J. , Liu F.S. , Shen P.S. , Chen G.D. , Lin L.Y. , Ho E.S.C. 
Published: November 2003

AbstractObjectives: To evaluate and compare the surgical outcome between the innovative tension‐free vaginal tape (TVT) and conventional pubovaginal sling (PVS) procedures using polypropylene mesh. Methods: Eighty consecutive women with urodynamic stress urinary incontinence (SUI), who chose to undergo either a TVT (n=23) or a PVS (n=57) procedure using polypropylene mesh based on financial consideration, were recruited for this study. The surgical results were analyzed and compared subjectively and objectively. Results: The mean follow‐up interval was 23 months for the TVT and 20 months for the PVS procedure (P=0.062). Postoperatively, SUI (91.3% vs. 93.0%), concomitant urge symptoms (85.0% vs. 85.3%) and the negative impact of incontinence and urogenital distress on patients’ quality of life (79.8% vs. 77.8%) (77.4% vs. 68.8%) had improved markedly. After a multivariable logistic regression analysis, the treatment outcome of SUI was found to be independent of the main effects of patient age, parity, concurrent gynecological surgeries, intrinsic sphincter deficiency, previous failed incontinence surgeries, and concomitant urge symptoms. However, it was significantly related to treatment procedures (TVT vs. PVS) and their interaction with patient body mass index (BMI). Based on the fitted logistic model, we see that TVT performs better than PVS when BMI is less than 27.27 kg/m2, and the advantage of TVT decreases as BMI increases. Conclusion: Both TVT and PVS procedures using polypropylene mesh are effective treatment modalities for female SUI. However, TVT was not as effective in treating overweight or obese women as PVS.
Indwelling urinary catheters in cesarean delivery
Authors: Ghoreishi J. 
Published: November 2003

AbstractObjectives:A prospective randomized study was used to determine the effect of urinary bladder catheterization on first‐void discomfort, time of ambulation, hospital stay, and urinary tract infection in women undergoing cesarean delivery.Methods:We randomly assigned 270 women delivered by cesarean section to urinary bladder catheterization or no catheterization. Prospective methods were used to assess patient discomfort with the first postoperative void after, time of ambulation, time of hospital stay, and need for recatheterization.Results:Of 135 women who did not receive an indwelling urinary catheter after cesarean delivery, six (4.4%) patients needed postoperation urinary catheterization. The time of first postoperative voiding was 8–11 h in 54 (42.5%) of cases. The ambulation time in the uncatheterized group was 6.8 h, vs. 12.9 h in the control group. Uncatheterized patients had a shorter hospital stay. Urinary tract infection was not assessed in this study.Conclusions:Routine use of indwelling urinary catheter in cesarean delivery patients with a stable hemodynamic condition is not necessary.
Serum levels of insulin, IGF‐1, and IGFBP‐1 in pre‐eclampsia and eclampsia
Authors: Ingec M. , Gursoy H.G. , Yildiz L. , Kumtepe Y. , Kadanali S. 
Published: November 2003

AbstractObjectives: To investigate whether the serum concentrations of insulin, insulin‐like growth factor‐1 (IGF‐1), and insulin‐like growth factor binding protein‐1 (IGFBP‐1) were altered in women with mild pre‐eclampsia, severe pre‐eclampsia, and eclampsia. Methods: In this prospective study, we investigated 20 mild pre‐eclamptic, 20 severe pre‐eclamptic, and 20 eclamptic patients in the third trimester. The control group consisted of 20 healthy pregnant women. Serum levels of insulin, IGF‐1, and IGFBP‐1 were measured. Results: In patients with eclampsia, serum levels of IGF‐1 were lower, and IGFBP‐1 were higher, respectively, than control and other study groups (P<0.001) The values of IGF‐1 in mild pre‐eclampsia and severe pre‐eclampsia were lower compared with control groups (both P<0.01), but there were no differences between mild and severe pre‐eclampsia. The serum levels of IGFBP‐1 in severe pre‐eclampsia were higher compared with control groups (P<0.01), but there was no statistical difference between mild pre‐eclampsia and other groups. Conclusions: IGF‐1 was lower, and IGFBP‐1 was higher in pre‐eclamptic and eclamptic patients than controls, these alterations were related to the severity of pre‐eclampsia.
Behavioral profile of L–741,741, a selective D4 dopamine receptor antagonist, in social encounters between male mice
Authors: Navarro J.F. , Luna G. , Pedraza C. 
Published: October 2003

AbstractAlthough the role of dopamine D1–D2–D3 receptors in the modulation of aggression has been extensively documented, there is not information with respect to the implication of D4 receptor. The aim of this study was to examine the acute effects of L–741,741 (0.75, 1.5 and 3 mg/kg, i.p), a selective D4 receptor antagonist, on social encounters between male mice using an ethopharmacological approach. Ten min of diadic interactions were staged between a singly housed and an anosmic mouse in a neutral area. These encounters were videotaped and the accumulated time allocated by subjects to ten broad behavioral categories was estimated. Besides other behaviors, the aggressive and motor behaviors were evaluated 30 min after injection using an ethologically based analysis. L–741,741 did not affect significantly offensive behaviors (threat and attack), as compared with the control group. Likewise, motor and anxiety‐related behaviors (such as social investigation, avoidance/flee or defense submission) were not altered after drug administration. These results suggest that dopamine D4 receptor is not involved in the modulation of aggressive behavior. Aggr. Behav. 29:552–557, 2003. © 2003 Wiley‐Liss, Inc.
Moral emotions and bullying: A cross‐national comparison of differences between bullies, victims and outsiders
Authors: Menesini Ersilia , Sanchez Virginia , Fonzi Ada , Ortega Rosario , Costabile Angela , Lo Feudo Giorgio 
Published: October 2003

AbstractThis study aims to analyse the role of moral emotions and reasoning in relation to children's behaviour in a bullying situation. On the basis of a peer nomination questionnaire [Salmivalli et al., 1996; Sutton and Smith, 1999], children from three different cities (Seville, Florence, and Cosenza) were assigned to one of three different status groups: bullies, victims, or outsiders. Subsequently they were interviewed about their feelings in relation to the task of putting themselves in the role of the bully in a bullying scenario. Specifically, emotions such as guilt and shame, expressed in a sense of moral responsibility, and indifference and pride, expressed in an attitude of moral disengagement, were investigated. Results showed significant differences between bullies, victims, and outsiders, with regard to moral disengagement, at both the affective and cognitive levels. Across the three cities, bullies, as compared to victims and outsiders, showed a higher level of disengagement emotions and motives when they were asked to put themselves in the role of bully. At a more detailed level, analyses of specific mechanisms of moral disengagement revealed that bullies possessed a main profile of egocentric reasoning. Besides the differences between bullies and victims, cross‐cultural differences were also present. Compared to children from Seville, children from the south of Italy (Cosenza) attributed higher disengagement to the bullies. Findings are discussed in relation to specific cultural characteristics of this area. Aggr. Behav. 29:515–530, 2003. © 2003 Wiley‐Liss, Inc.
Rough‐and‐tumble play in human children
Authors: Scott Eric , Panksepp Jaak 
Published: October 2003

AbstractRough and tumble (R&T) play is a unique set of behaviors that can be reliably distinguished from aggression and other childhood activities. Although it may be the most fundamental form of play, it has received comparatively little experimental attention in the human species. Forty children, ages three to six, were allowed to play in pairs (10 male pairs, 10 female pairs) during a 30 minute videotaped session with no toys available while music played in the background during every other five‐minute time period. The incidence frequency of children's play and related behavioral activities were scored using 20 behavioral categories. The major findings show only modest gender differences in the frequency of play behaviors in such controlled social encounters; the main difference is that boys engaged in slightly more physical play solicitations than girls. Music facilitated General Motor Activities (e.g., Running and Walking behaviors), but not specific R&T play actions (e.g., Wrestling, Ventral and Dorsal contacts). Finally, most play behaviors as well as general activities declined systematically over the course of each recording session. This experiment highlights how human social play can be systematically studied in a controlled laboratory setting. Aggr. Behav. 29:539–551, 2003. © 2003 Wiley‐Liss, Inc.
Examining antisocial behavior through the lens of the five factor model of personality
Authors: Miller Joshua D. , Lynam Donald , Leukefeld Carl 
Published: October 2003

AbstractThe current study attempts to provide greater precision in understanding how personality is related to antisocial behavior. Specifically, we examined the relations between the facets (subordinate traits) from three domains (superordinate dimensions): Neuroticism, Agreeableness, and Conscientiousness, of the Five Factor Model and five outcome variables: stability of conduct problems, variety of conduct problems, onset of conduct problems, aggression, and antisocial personality disorder symptoms. These relations were examined in a community sample of 481 individuals. These three personality dimensions were chosen for exploration due to their consistent relations, at the domain level, with antisocial behaviors. The results from this study suggest that the facets from the dimension of Agreeableness are the most consistently related to all five outcomes. However, the facets from all three domains made significant contributions. Overall, three personality traits stood out as being the strongest and most consistent predictors: low straightforwardness, low compliance, and low deliberation. Implications for prevention and intervention are discussed. Aggr. Behav. 29:497–514, 2003. © 2003 Wiley‐Liss, Inc.
Bindungsaffinitäten von Wirt‐Gast‐, Protein‐Ligand‐ und Protein‐Übergangszustands‐Komplexen
Authors: Houk Kendall N. , Leach Andrew G. , Kim Susanna P. , Zhang Xiyun 
Published: October 2003

AbstractDie Affinitäten von Wirten – ausgehend von kleinen synthetischen Cavitanten bis hin zu großen Proteinen – für organische Moleküle sind gut dokumentiert. Die mittleren Assoziationskonstanten für die Bindung organischer Moleküle durch Cyclodextrine, synthetische Wirte und Albumine in Wasser sowie von katalytischen Antikörpern oder Enzymen für Substrate betragen im Allgemeinen 103.5±2.5 M−1. Die Bindungsaffinitäten steigen bei der Komplexierung von Übergangszuständen und biologischen Antigenen durch Antikörper oder von Enzymen durch Inhibitoren auf 108±2 M−1 und auf 1016±4 M−1 für Enzym‐Übergangszustands‐Komplexe. Die Gründe für die unterschiedlichen Stabilitäten dieser Wirt‐Gast‐Systeme sollen hier untersucht werden, und wir beschreiben Ansätze zur computergestützten Analyse der Wirt‐Gast‐Komplexbildung in Lösung. Bei vielen Komplexklassen besteht eine ungefähre Korrelation der Bindungsaffinität mit der Größe der Oberfläche, die bei der Komplexierung vergraben wird. Enzyme folgen dieser Korrelation nicht, sondern binden Übergangszustände sehr viel stärker als es anhand der Oberfläche zu erwarten wäre.
Elektrochemische und photochemische Steuerung der Wirt‐Gast‐Komplexierung an Oberflächen
Authors: Cooke Graeme 
Published: October 2003

AbstractDer Einsatz von Elektro‐ und Photochemie zur Modulation supramolekularer Wechselwirkungen zwischen Wirt‐Gast‐Systemen in Lösung ist ein aktuelles Forschungsgebiet. Die Geschwindigkeit und Reversibilität elektrochemisch oder photochemisch ausgelöster Wechselwirkungen ermöglichten Aufbau und Modulation neuartiger molekularer Maschinen in Lösung. In den letzten Jahren wurden große Fortschritte bei der Übertragung dieser Systeme auf die Festphase erzielt. Dadurch wurde die Entwicklung von Bausteinen erleichtert, die auf einen Reiz als elektronische Einheit reagieren. So können Oberflächen aufgebaut werden, die auf äußere Signale reagieren. Diese Systeme können in hoch entwickelten Materialien für die Nanotechnologie eingesetzt werden.
Crystallographic report: Bis(tetraphenylphosphonium) bis(dichloro‐nitratophenylstannate)methane, [Ph4P+]2 [(PhCl2(NO3)Sn)2CH2]2−
Authors: Jurkschat Klaus , Reeske Gregor , Schürmann Marcus , Tiekink Edward R. T. 
Published: October 2003

AbstractEach tin atom of the title compound is five‐coordinate, defined by 2C, 2Cl and 1O atoms, and shows a distorted square pyramidal configuration stabilized by intramolecular Sn· · ·O or Sn· · ·Cl interactions. Both nitrate anions coordinate the tin atoms in a monodentate mode. Copyright © 2003 John Wiley & Sons, Ltd.
Synthesis and characterization of triarylphosphine complexes of zinc(II) halides
Authors: Chauhan Ashok K. S. , Singh Narendra , Srivastava Ramesh C. 
Published: October 2003

AbstractBoth 1:1 and 1:2 complexes are formed by zinc(II) halides and triarylphosphines unless electronic and/or steric factors intervene. Tri‐p‐chlorophosphine (a weaker base than PPh3) forms only a 1:1 complex, whereas bulky tri‐(ortho‐substituted phenyl)phosphines do not react. The complexes ZnX2PR3 and ZnX2(PR3)2 have been characterized by elemental analyses, conductance, far‐IR and (in a few cases) Raman spectral studies. The Zn–X and Zn–P stretching and Zn–X bending vibrational frequencies have been assigned in the complexes with a pseudo‐tetrahedral structure of C2v symmetry. Copyright © 2003 John Wiley & Sons, Ltd.
1,1‐Organoboration of bis(trimethylstannyl)ethyne with trimethylsilyl‐ and dimethylsilyl‐dialkylboryl‐substituted alkenes: organometallic‐substituted allenes
Authors: Wrackmeyer Bernd , Tok Oleg L. , Bhatti Moazzam H. , Ali Saqib 
Published: October 2003

AbstractThe reactions of bis(trimethylstannyl)ethyne, Me3Sn–CC–SnMe3 (4), with trimethylsilyl‐ or dimethylsilyl‐dialkylboryl‐substituted alkenes 1–3 afford organometallic‐substituted allenes 5, 6 and 8, 9 in high yield. In the case of (E)‐2‐trimethylsilyl‐3‐diethylboryl‐2‐pentene (1), a butadiene derivative 7 could be detected as an intermediate prior to rearrangement into the allene. All reactions were monitored by 29Si and 119Sn NMR, and the products were characterized by an extensive NMR data set (1H, 11B, 13C, 29Si, 119Sn NMR). Copyright © 2003 John Wiley & Sons, Ltd.
Synthesis and cytotoxicity of silylalkylthio‐substituted N‐heterocycles and their hydroselenites
Authors: Arsenyan Pavel , Rubina Kira , Shestakova Irina , Abele Edgars , Abele Ramona , Domracheva Ilona , Nesterova Alena , Popelis Juris , Lukevics Edmunds 
Published: October 2003

AbstractNew hydroselenites of the different silylalkylthio‐substituted N‐heterocycles have been prepared by the reaction of selenium dioxide with N‐heterocycles in an aqueous medium. Their structure was confirmed by 1H, 13C, and 77Se NMR data. Most of these silylalkylthio‐substituted N‐heterocycles and their hydroselenites have an expressed cytotoxic activity on the MG‐22A (mouse hepatoma), HT‐1080 (human fibrosarcoma), B16 (mouse melanoma), and Neuro 2A (mouse neuroblastoma) cell lines. Some of the hydroselenites exhibit free‐radical protection simultaneously with a high cytotoxic effect. The substances studied were also active in vivoagainst sarcoma S‐180. Copyright © 2003 John Wiley & Sons, Ltd.
Practical generation of 3,5‐dimethoxybenzyllithium: application to the synthesis of 5‐substituted‐resorcinols
Authors: Azzena Ugo , Dettori Giovanna , Idini Maria Vittoria , Pisano Luisa , Sechi Grazia 
Published: October 2003

AbstractReductive lithiation of 3,5‐dimethoxybenzyl methyl ether was successfully performed with lithium wire and a catalytic amount of naphthalene in dry tetrahydrofuran at −15°C, leading to the quantitative generation of 3,5‐dimethoxybenzyllithium. This organometallic compound, which can be stored for at least 24 h, was trapped with a variety of different electrophiles, including, besides aldehydes, non‐functionalized and functionalized alkyl halides and an epoxide. Accordingly, it is a useful intermediate in the synthesis of 5‐substituted natural and non‐natural resorcinols. Copyright © 2003 John Wiley & Sons, Ltd.
Aminoethynyl‐silanes, ‐germanes and ‐stannanes: novel organometallic‐substituted enamines via 1,1‐organoboration
Authors: Wrackmeyer Bernd , Tok Oleg L. , Guldner Gudrun , Gruener Sergej V. 
Published: October 2003

AbstractThe reactions of diethylaminoethynyl(trimethyl)silane (1), bis(diethylaminoethynyl)methylsilane (2), diethylaminoethynyl(trimethyl)germane (3), dimethylaminoethynyl(triethyl)germane (4), diethylaminoethynyl(trimethyl)stannane (5) and methyl(phenyl)aminoethynyl(trimethyl)stannane (6) with trialkylboranes [BEt3 (7b), BPr3 (7c), BiPr3 (7d) and 9‐alkyl‐9‐borabicyclo[3.3.1]nonanes 9‐Me‐9‐BBN (8a) and 9‐Et‐9‐BBN (8b)] were studied. The alkynes 1 and 2 did not react even with boiling BEt3, whereas the reactions of 3–6 afforded mainly novel enamines [(E)‐1‐amino‐1‐trialkylgermyl‐2‐dialkylboryl‐alkenes (9, 10), (E)‐1‐diethylamino‐1‐trimethylstannyl‐2‐dialkylboryl‐alkenes (11, 12), (E)‐1‐methyl(phenyl)amino‐1‐trimethylstannyl‐2‐dialkylboryl‐alkenes (13, 14)]. This particular stereochemistry is unusual for products from 1,1‐organoboration reactions, indicating a special influence of the amino group. The starting materials and products were characterized by multinuclear magnetic resonance spectroscopy (1H, 11B, 13C, 15N, 29Si, 119Sn NMR). Copyright © 2003 John Wiley & Sons, Ltd.