bluuebunny/crossref_metadata_2025_split huggingface dataset:
The use of whole body computed tomography does not lead to increased 24-h mortality in severely injured patients in circulatory shock
Authors: Hanzalova Ivana , Bourgeat Mylène , Demartines Nicolas , Ageron François-Xavier , Zingg Tobias 
Published: January 2024

AbstractThe Advanced Trauma Life Support (ATLS) approach is generally accepted as the standard of care for the initial management of severely injured patients. While whole body computed tomography (WBCT) is still considered a contraindication in haemodynamically unstable trauma patients, there is a growing amount of data indicating the absence of harm from cross sectional imaging in this patient group. Our study aimed to compare the early mortality of unstable trauma patients undergoing a WBCT during the initial workup with those who did not. Single-center retrospective observational study based on the local trauma registry including 3525 patients with an ISS > 15 from January 2008 to June 2020. We compared the 24-h mortality of injured patients in circulatory shock undergoing WBCT with a control group undergoing standard workup only. Inclusion criteria were the simultaneous presence of a systolic blood pressure < 100 mmHg, lactate > 2.2 mmol/l and base excess < − 2 mmol/l as surrogate markers for circulatory shock. To control for confounding, a propensity score matched analysis with conditional logistic regression for adjustment of residual confounders and a sensitivity analysis using inverse probability weighting (IPW) with and without adjustment were performed. Of the 3525 patients, 161 (4.6%) fulfilled all inclusion criteria. Of these, 132 (82%) underwent WBCT and 29 (18%) standard work-up only. In crude and matched analyses, no difference in early (24 h) mortality was observed (WBCT, 23 (17.4%) and no-WBCT, 8 (27.6%); p = 0.21). After matching and adjustment for main confounders, the odds ratio for the event of death at 24 h in the WBCT group was 0.36 (95% CI 0.07–1.73); p = 0.20. In the present study, WBCT did not increase the risk of death at 24 h among injured patients in shock. This adds to the growing data indicating that WBCT may be offered to trauma patients in circulatory shock without jeopardizing early survival.
Identification of gene signatures and molecular mechanisms underlying the mutual exclusion between psoriasis and leprosy
Authors: Lu You-Wang , Dong Rong-Jing , Yang Lu-Hui , Liu Jiang , Yang Ting , Xiao Yong-Hong , Chen Yong-Jun , Wang Rui-Rui , Li Yu-Ye 
Published: January 2024

AbstractLeprosy and psoriasis rarely coexist, the specific molecular mechanisms underlying their mutual exclusion have not been extensively investigated. This study aimed to reveal the underlying mechanism responsible for the mutual exclusion between psoriasis and leprosy. We obtained leprosy and psoriasis data from ArrayExpress and GEO database. Differential expression analysis was conducted separately on the leprosy and psoriasis using DEseq2. Differentially expressed genes (DEGs) with opposite expression patterns in psoriasis and leprosy were identified, which could potentially involve in their mutual exclusion. Enrichment analysis was performed on these candidate mutually exclusive genes, and a protein–protein interaction (PPI) network was constructed to identify hub genes. The expression of these hub genes was further validated in an external dataset to obtain the critical mutually exclusive genes. Additionally, immune cell infiltration in psoriasis and leprosy was analyzed using single-sample gene set enrichment analysis (ssGSEA), and the correlation between critical mutually exclusive genes and immune cells was also examined. Finally, the expression pattern of critical mutually exclusive genes was evaluated in a single-cell transcriptome dataset. We identified 1098 DEGs in the leprosy dataset and 3839 DEGs in the psoriasis dataset. 48 candidate mutually exclusive genes were identified by taking the intersection. Enrichment analysis revealed that these genes were involved in cholesterol metabolism pathways. Through PPI network analysis, we identified APOE, CYP27A1, FADS1, and SOAT1 as hub genes. APOE, CYP27A1, and SOAT1 were subsequently validated as critical mutually exclusive genes on both internal and external datasets. Analysis of immune cell infiltration indicated higher abundance of 16 immune cell types in psoriasis and leprosy compared to normal controls. The abundance of 6 immune cell types in psoriasis and leprosy positively correlated with the expression levels of APOE and CYP27A1. Single-cell data analysis demonstrated that critical mutually exclusive genes were predominantly expressed in Schwann cells and fibroblasts. This study identified APOE, CYP27A1, and SOAT1 as critical mutually exclusive genes. Cholesterol metabolism pathway illustrated the possible mechanism of the inverse association of psoriasis and leprosy. The findings of this study provide a basis for identifying mechanisms and therapeutic targets for psoriasis.
Added value of dynamic contrast-enhanced MR imaging in deep learning-based prediction of local recurrence in grade 4 adult-type diffuse gliomas patients
Authors: Yoon Jungbin , Baek Nayeon , Yoo Roh-Eul , Choi Seung Hong , Kim Tae Min , Park Chul-Kee , Park Sung-Hye , Won Jae-Kyung , Lee Joo Ho , Lee Soon Tae , Choi Kyu Sung , Lee Ji Ye , Hwang Inpyeong , Kang Koung Mi , Yun Tae Jin 
Published: January 2024

AbstractLocal recurrences in patients with grade 4 adult-type diffuse gliomas mostly occur within residual non-enhancing T2 hyperintensity areas after surgical resection. Unfortunately, it is challenging to distinguish non-enhancing tumors from edema in the non-enhancing T2 hyperintensity areas using conventional MRI alone. Quantitative DCE MRI parameters such as Ktrans and Ve convey permeability information of glioblastomas that cannot be provided by conventional MRI. We used the publicly available nnU-Net to train a deep learning model that incorporated both conventional and DCE MRI to detect the subtle difference in vessel leakiness due to neoangiogenesis between the non-recurrence area and the local recurrence area, which contains a higher proportion of high-grade glioma cells. We found that the addition of Ve doubled the sensitivity while nonsignificantly decreasing the specificity for prediction of local recurrence in glioblastomas, which implies that the combined model may result in fewer missed cases of local recurrence. The deep learning model predictive of local recurrence may enable risk-adapted radiotherapy planning in patients with grade 4 adult-type diffuse gliomas.
An efficient and robust system for human following scenario using differential robot
Authors: Zhu Jiangchao , Ma Changjia , Xu Chao , Gao Fei 
Published: January 2024

AbstractA novel system for human following using a differential robot, including an accurate 3‐D human position tracking module and a novel planning strategy that ensures safety and dynamic feasibility, is proposed. The authors utilise a combination of gimbal camera and LiDAR for long‐term accurate human detection. Then the planning module takes the target's future trajectory as a reference to generate a coarse path to ensure the following visibility. After that, the trajectory is optimised considering other constraints and following distance. Experiments demonstrate the robustness and efficiency of our system in complex environments, demonstrating its potential in various applications.
Update of SB9 orbits using HERMES/Mercator radial velocities
Authors: Merle T. , Pourbaix D. , Jorissen A. , Siopis C. , Van Eck S. , Van Winckel H. 
Published: January 2024

Aims. By combining astrometric orbits (delivered in large numbers by the Gaίa mission) with spectroscopic orbits for systems with two observable spectra (SB2), it is possible to derive the masses of both stellar components. However, to get masses with a good accuracy requires accurate spectroscopic orbits, which is the primary aim of the present paper. A subsidiary aim is to discover SB2 systems hiding among known SB1 systems and even though this search may often prove unsuccessful, the acquired radial velocities may still be used to improve the existing spectroscopic orbits.
Methods. New radial velocities for 58 binary systems from the Ninth Catalogue of Spectroscopic Binary Orbits (SB9), obtained using the high-resolution HERMES spectrograph installed on the 1.2 m Mercator telescope, were used to possibly identify hitherto undetected SB2 systems. For SB1 systems with inaccurate orbits, we used these new radial-velocity measurements to improve the orbital accuracy.
Results. This study provides 51 orbits (41 SB1 and 10 SB2) that have been improved with respect to the solution listed in the SB9 catalogue, out of the 58 SB9 orbits studied, which belong to 56 stellar systems. Among them, there are five triple and four quadruple systems. Despite the high resolution of HERMES, the only system we detected as anew SB2 system is HIP 115142 A. The B component of the visual binary HIP 92726 has now been found to be a spectroscopic system as well, which makes HIP 92726 a newly discovered quadruple system (SB 1+SB 1). Moreover, the high resolution of HERMES has enabled us to better isolate the signature of the secondary component of HIP 12390, HIP 73182, and HIP 111170. Thus, we derived more accurate masses for them. Among the 30 SB also present in Gaia Data Release 3 (DR3), with periods shorter than the Gaia DR3 time span (~1000 d), only five had been flagged as binaries by DR3. Various DR3 selection criteria are responsible for this discrepancy.
Adaptive data reduction workflows for astronomy: The ESO Data Processing System (EDPS)
Authors: Freudling W. , Zampieri S. , Coccato L. , Podgorski S. , Romaniello M. , Modigliani A. , Pritchard J. 
Published: January 2024

Context. Astronomical data reduction is usually done via processing pipelines that consist of a series of individual processing steps that can be executed one at a time. These processing steps are then strung together into workflows and fed with data to address a particular processing goal. Examples of such pipeline processing goals are the quality control of incoming data from telescopes, unsupervised production of science and calibration products for an archive, and supervised data reduction to serve the specific science goals of a scientist. For each of these goals, individual workflows need to be developed. These workflows need to evolve when the pipeline, observing strategies, or calibration plans change. Writing and maintaining such a collection of workflows is therefore a complex and expensive task.
Aims. In this paper we propose a data processing system that automatically derives processing workflows for different use cases from a single specification of a cascade of processing steps.
Methods. The system works by using formalised descriptions of data processing pipelines that specify the input and output of each processing step. Inputs can be existing data or the output of a previous step. The rules for selecting the most appropriate input data are directly attached to the description.
Results. A version of the proposed system has been implemented as the ESO Data Processing System (EDPS) in the Python language. The specification of processing cascades and data organisation rules use a restrictive set of Python classes, attributes, and functions.
Conclusions. The EDPS implementation of the proposed system was used to demonstrate that it is possible to automatically derive from a single specification of a pipeline processing cascade the workflows that the European Southern Observatory uses for quality control, archive production, and specialised science reduction. The EDPS will be used to replace all data reduction systems using different workflow specifications that are currently in use at the European Southern Observatory.
The Lockman–SpReSO project
Authors: González-Otero Mauro , Padilla-Torres Carmen P. , González-Serrano José Ignacio , Cepa Jordi , María Pérez García Ana , Jesús González J. , Benítez Erika , Bongiovanni Ángel , Cerviño Miguel , Cruz-González Irene , Gallego Jesús , Herrera-Endoqui Martín , Ibarra-Medel Héctor J. , Krongold Yair , Lara-López Maritza A. , Nadolny Jakub , Alenka Negrete Castalia , Pérez-Martínez Ricardo , Pović Mirjana , Sánchez-Portal Miguel , Cedrés Bernabé , de Diego José A. , Hernández-Toledo Héctor , Navarro Martínez Rocío 
Published: January 2024

Context. The Lockman–SpReSO project is an optical spectroscopic survey of 956 far-infrared (FIR) objects within the Lockman Hole field limited by magnitude RC(AB) < 24.5. Fe II and Mg II absorption lines have been detected in 21 out of 456 objects with a determined spectroscopic redshift in the catalogue. The redshifts of these objects are in the range 0.5 ≲ z ≲ 1.44.
Aims. The aim of this study is to investigate material ejection from star-forming regions and material infall into galaxies by analysing the Fe II and Mg II absorption lines. Additionally, we explore whether the correlations found in previous studies between these galactic wind velocities, line equivalent widths (EWs), and galaxy properties such as stellar mass (M*), star formation rate (SFR), and specific star formation rate (sSFR) are valid for a sample with FIR-selected objects. The objects analysed span an M* range of 9.89 < log(M*/M⊙) < 11.50 and an SFR range of 1.01 < log(SFR) < 2.70.
Methods. We performed measurements of the Mg IIλλ2796, 2803, Mg Iλ2852, Fe IIλλ2374, 82, Fe IIλλ2586, 2600, and Fe IIλ2344 spectral lines present in the spectra of the selected sample to determine the EW and velocity of the flows observed in the star-forming galaxies. Subsequently, we conducted 107 bootstrap simulations using the Spearman’s rank correlation coefficient (ρs) to explore correlations with galaxy properties. Furthermore, we calculated the covering factor, gas density, and optical depth for the measured Fe II doublets.
Results. Our analysis reveals strong correlations between the EW of Mg II lines and both M* (ρs = 0.43, 4.5σ) and SFR (ρs = 0.42, 4.4σ). For the Fe II lines, we observed strong correlations between the EW and SFR (ρs ∼ 0.65, > 3.9σ), with a weaker correlation for M* (ρs ∼ 0.35, > 1.9σ). No notable correlations were found between velocity measurements of the Mg II line and M*, SFR, or sSFR of the objects (ρs ∼ 0.1). However, a strong negative correlation was found between the velocity of the Fe II lines and the SFR of the galaxies (ρs ∼ −0.45, ∼3σ). Our results align with those of previous studies, although only FIR-selected objects are investigated here. Finally, we detect a candidate ‘loitering outflow’, a recently discovered subtype of the iron low-ionisation broad absorption line (FeLoBAL) quasars, at a redshift of z = 1.4399, exhibiting emission in C III] and low line velocities (|v|≲200 km s−1).
TIPSY: Trajectory of Infalling Particles in Streamers around Young stars
Authors: Gupta Aashish , Miotello Anna , Williams Jonathan P. , Birnstiel Til , Kuffmeier Michael , Yen Hsi-Wei 
Published: January 2024

Context. Elongated trails of infalling gas, often referred to as “streamers,” have recently been observed around young stellar objects (YSOs) at different evolutionary stages. This asymmetric infall of material can significantly alter star and planet formation processes, especially in the more evolved YSOs.
Aims. In order to ascertain the infalling nature of observed streamer-like structures and then systematically characterize their dynamics, we developed the code TIPSY (Trajectory of Infalling Particles in Streamers around Young stars).
Methods. Using TIPSY, the streamer molecular line emission is first isolated from the disk emission. Then the streamer emission, which is effectively a point cloud in three-dimensional (3D) position–position–velocity space, is simplified to a curve-like representation. The observed streamer curve is then compared to the theoretical trajectories of infalling material. The best-fit trajectories are used to constrain streamer features, such as the specific energy, the specific angular momenta, the infall timescale, and the 3D morphology.
Results. We used TIPSY to fit molecular-line ALMA observations of streamers around a Class II binary system, S CrA, and a Class I/II protostar, HL Tau. Our results indicate that both of the streamers are consistent with infalling motion. For the S CrA streamer, we could constrain the dynamical parameters well and find it to be on a bound elliptical trajectory. On the other hand, the fitting uncertainties are substantially higher for the HL Tau streamer, likely due to the smaller spatial scales of the observations. TIPSY results and mass estimates suggest that S CrA and HL Tau are accreting material at a rate of ≳27 Mjupiter Myr–1 and ≳5 Mjupiter Myr–1, respectively, which can significantly increase the mass budget available to form planets.
Conclusions. TIPSY can be used to assess whether the morphology and kinematics of observed streamers are consistent with infalling motion and to characterize their dynamics, which is crucial for quantifying their impact on the protostellar systems.
Numerical simulations of turbulence in prominence threads induced by torsional oscillations
Authors: Díaz-Suárez Sergio , Soler Roberto 
Published: January 2024

Context.Threads are the main constituents of prominences. They are dynamic structures that display oscillations, usually interpreted as magnetohydrodynamic (MHD) waves. Moreover, instabilities such as the Kelvin–Helmholtz instability (KHI) have also been reported in prominences. Both waves and instabilities may affect the thermodynamic state of the threads.Aims.We investigate the triggering of turbulence in prominence threads caused by the nonlinear evolution of standing torsional Alfvén waves. We study the heating in the partially ionized prominence plasma as well as possible observational signatures of this dynamics.Methods.We modeled a prominence thread as a radially and longitudinally nonuniform cylindrical flux tube with a constant axial magnetic field embedded in a much lighter and hotter coronal environment. We perturbed the flux tube with the longitudinally fundamental mode of standing torsional Alfvén waves. We numerically solved the three-dimensional (3D) MHD equations to study the temporal evolution in both ideal and dissipative scenarios. In addition, we performed forward modeling to calculate the synthetic Hαimaging.Results.The standing torsional Alfvén waves undergo phase-mixing owing to the radially nonuniform density. The phase-mixing generates azimuthal shear flows, which eventually trigger the KHI and, subsequently, turbulence. When nonideal effects are included, the obtained plasma heating is very localized in an annulus region at the thread boundary and does not increase the temperature in the cool core. Instead, the average temperature in the thread decreases owing to the mixing of internal and external plasmas. In the synthetic observations, first we observe periodic pulsations in the Hαintensity caused by the integration of the phase-mixing flows along the line of sight. Later, fine strands that may be associated with the KHI vortices are seen in the synthetic Hαimages.Conclusions.Turbulence can be generated by standing torsional Alfvén waves in prominence threads after the triggering of the KHI, although this mechanism is not enough to heat such structures. Both the phase-mixing stage and the turbulent stage of the simulated dynamics could be discernible in high-resolution Hαobservations.
KMT-2023-BLG-0416, KMT-2023-BLG-1454, KMT-2023-BLG-1642: Microlensing planets identified from partially covered signals
Authors: Han Cheongho , Udalski Andrzej , Lee Chung-Uk , Zang Weicheng , Albrow Michael D. , Chung Sun-Ju , Gould Andrew , Hwang Kyu-Ha , Jung Youn Kil , Ryu Yoon-Hyun , Shvartzvald Yossi , Shin In-Gu , Yee Jennifer C. , Yang Hongjing , Cha Sang-Mok , Kim Doeon , Kim Dong-Jin , Kim Seung-Lee , Lee Dong-Joo , Lee Yongseok , Park Byeong-Gon , Pogge Richard W. , Mróz Przemek , Szymański Michał K. , Skowron Jan , Poleski Radosław , Soszyński Igor , Pietrukowicz Paweł , Kozłowski Szymon , Rybicki Krzysztof A. , Iwanek Patryk , Ulaczyk Krzysztof , Wrona Marcin , Gromadzki Mariusz , Mróz Mateusz 
Published: January 2024

Aims. We investigate the 2023 season data from high-cadence microlensing surveys with the aim of detecting partially covered shortterm signals and revealing their underlying astrophysical origins. Through this analysis, we ascertain that the signals observed in the lensing events KMT-2023-BLG-0416, KMT-2023-BLG-1454, and KMT-2023-BLG-1642 are of planetary origin.
Methods. Considering the potential degeneracy caused by the partial coverage of signals, we thoroughly investigate the lensing-parameter plane. In the case of KMT-2023-BLG-0416, we have identified two solution sets, one with a planet-to-host mass ratio of q ~ 10−2 and the other with q ~ 6 × 10−5, within each of which there are two local solutions emerging due to the inner-outer degeneracy. For KMT-2023-BLG-1454, we discern four local solutions featuring mass ratios of q ~ (1.7−4.3) × 10−3. When it comes to KMT-2023-BLG-1642, we identified two locals with q ~ (6 − 10) × 10−3 resulting from the inner-outer degeneracy.
Results. We estimate the physical lens parameters by conducting Bayesian analyses based on the event time scale and Einstein radius. For KMT-2023-BLG-0416L, the host mass is ~0.6 M⊙, and the planet mass is ~(6.1−6.7) MJ according to one set of solutions and ~0.04 MJ according to the other set of solutions. KMT-2023-BLG-1454Lb has a mass roughly half that of Jupiter, while KMT-2023-BLG-1646Lb has a mass in the range of between 1.1 to 1.3 times that of Jupiter, classifying them both as giant planets orbiting mid M-dwarf host stars with masses ranging from 0.13 to 0.17 solar masses.
Indication of a fast ejecta fragment in the atomic cloud interacting with the southwestern limb of SN 1006
Authors: Giuffrida R. , Miceli M. , Ravikularaman S. , Phan V. H. M. , Gabici S. , Mertsch P. , Orlando S. , Bocchino F. 
Published: January 2024

Context. Supernova remnants interacting with molecular and atomic clouds are interesting X-ray sources for studies of broadband nonthermal emission. X-ray line emission in these systems can be produced by different processes, such as low-energy cosmic rays (LECRs) interacting with the cloud and fast ejecta fragments moving in the cloud.
Aims. This paper is aimed at studying the origin of the non-thermal X-ray emission of the southwestern limb of SN 1006 beyond the main shock to determine whether the emission is due to LECRs diffusing in the cloud or to ejecta knots moving into the cloud.
Methods. We analyzed the X-ray emission of the southwestern limb of SN 1006, where the remnant interacts with an atomic cloud, using three different X-ray telescopes: NuSTAR, Chandra, and XMM-Newton. We also performed a combined spectro-imaging analysis of this region.
Results. Our analysis of the nonthermal X-ray emission of the southwestern limb of SN 1006 interacting with an atomic cloud has led to the detection of an extended X-ray source in the atomic cloud, approximately 2 pc upstream of the shock front. The source is characterized by a hard continuum (described by a power law with photon index Γ ∼ 1.4) and by Ne, Si, and Fe emission lines. The observed flux suggests that the origin of the X-ray emission is not associated with LECRs interacting with the cloud. On the other hand, the spectral properties of the source, together with the detection of an IR counterpart visible with Spitzer-MIPS at 24 μm, are in good agreement with the general expectations for a fast ejecta fragment moving within the atomic cloud.
Conclusions. We detected X-ray and IR emission from a possible ejecta fragment, with an approximate radius of 1 × 1017 cm and approximate mass of 10−3 M⊙ at about 2 pc out of the shell of SN 1006, in the interaction region between the southwestern limb of the remnant and the atomic cloud.