bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Anti-Nazi League, ‘Another White Organisation’? British Black Radicals against Racial Fascism
Authors: Hancox Alfie 
Published: October 2023

Abstract
This article explores how Britain’s Black Power movement challenged the political outlook of the anti-fascist left in the 1960s–70s. While the established left interpreted the National Front (NF) as an aberrant threat to Britain’s social democracy, Black political groups foregrounded the systemic racial violence of the British state. By addressing intensifying racial oppression during a critical early phase in the transition to neoliberalism, they prefigured Stuart Hall’s analysis of ‘authoritarian populism’. The British Black Power movement especially criticised the high-profile Anti-Nazi League (ANL) for its singular focus on the NF, which was framed as a revived Hitlerite peril. For British Black radicals, the larger strategic problem was the populist racism, inflected by imperial nostalgia, which propelled Thatcher’s New Right to power. Instead of narrow Nazi analogies, they related the re-emergence of white nationalism to British social democracy’s racist treatment of Black immigrants, as well as its neocolonial role abroad.
Behavioral activity and range patterns of the endemic Gelada monkey (Theropithecus gelada) in and around Jer Silase Monastery in North Shoa Zone, Ethiopia
Authors: Desalegn Tamenut 
Published: October 2023

Abstract
The present study investigated the activity, range, and habitat utilization patterns of the Endemic Gelada Monkey (Theropithecus gelada) in and around Jer Silase Monastery in North Shoa Zone, Ethiopia. The study was conducted from January 2021 to October 2021 by considering the dry and wet seasons and stratifying the study area into natural forest, cliff/rocky, and farmland habitats. An instantaneous scan sampling method was employed to collect behavioral data. The activity patterns of three selected focal groups of Gelada monkeys were studied. GPS points of their predominant behavioral activities were recorded daily every 15 minutes from 7:00 to 18:00 for 12 days every month. A total of 5,592 individual activity records were obtained from 2312 scan samplings taken over 120 study days. Feeding comprised 54.52% of the activity time, followed by moving at 20.67% and socialization at 11.95%. A multivariate analysis of variance (MANOVA) revealed that the time allocated to different activity types varied significantly over the year with the month (Roy’s Largest Root = 2.7, F4,22 = 13.2, p < 0.001, partial η2 = 0.653). The longest mean monthly travel distance was 2817.61 ± 582.57 m, recorded at the Cliff/rocky habitat during the wet season. Gelada monkeys’ daily range length and home range size extended more in the dry season. These findings may be explained by reduced habitat quality associated with livestock grazing, agricultural expansion, and charcoal production. Therefore, appropriate conservation measures should be implemented to minimize such adverse effects and conserve the endemic Gelada Monkey.
The Sign of Jonah
Authors: Oltvai Kristóf 
Published: October 2023

Abstract
The dialectical-theological origins of the politically- and ethically-charged concept of alterity are well-known within the philosophy of religion. Intellectual histories of this concept tie it too exclusively to the notion of distance or διάστασις in Karl Barth’s early Römerbrief, however, and so miss Barth’s Trinitarian reinterpretation of God’s otherness in his later work. Taking as my hermeneutical key a cipher, the ‘sign of Jonah,’ that emerges in Church Dogmatics IV/1, I show that Barth’s mature doctrines of temporality and filiation understand alterity as a moment of divine life. Jesus’ agony in the garden of Gethsemane marks the climax of Barth’s self-reinterpretation: world history inheres within the Christological situation of paternal abandonment. The political-theological conclusions Barth draws from the ‘sign of Jonah’ dovetail with alterity discourses’ antitotalitarian aspirations but suggest that these aspirations’ structural coherence rest on the magisterial Reformers’ Christological and ecclesiological commitments.
The fate of the Najdi manuscripts after the fall of al-Dirʿiyya
Authors: Al-angari Hamad ibn Abdallah 
Published: October 2023

Abstract
This paper seeks to shed light on the copying of manuscripts in Najd in central Arabia during the period prior to the fall of al-Dirʿiyya in 1818 and the fate of those manuscripts after that momentous event. It begins by a consideration of the movement of copying manuscripts in Najd during the era of the First Saudi State in the 18th century, including the reasons for which manuscripts were copied, the types of manuscripts copied, and the sources of those manuscripts. Attention is then given to the effect the fall of al-Dirʿiyya had on intellectual life in Najd, including the destruction of the existing book repositories and the transfer of many manuscript copies outside the borders of Najd, or their total loss or destruction. This paper will attempt to offer answers regarding the fate of those manuscripts, by following the progress of several of them and determining what happened to them. This will be done by consulting the relevant sources, particularly the available archival records, as well as following up on those that are to be found within Saudi Arabia itself or beyond its borders. The article includes a list of Najdi manuscripts preserved worldwide.
Traditional Architectural Techniques in Popular Proverbs of the Najd Region
Authors: ʿAbd Allāh al-Sadḥān Musāʿid ibn 
Published: October 2023

Abstract
This article seeks to examine popular proverbs from the central Arabian region of Najd in order to collect evidence for traditional architecture in the region. It will be seen that popular proverbs are a rich documentary source for understanding architectural heritage, including but not limited to, the types of buildings represented in the traditional built heritage of Najd, the distinguishing characteristics of those buildings, their constituent elements, materials used in construction, tools, and tradesmen. Folk literature in general, and proverbs in particular, are seen are seen to be a valuable, although non-traditional, source of information that springs from the depths of the indigenous culture itself.
Mesoscale Influences of Land Use, Topography, Antecedent Rainfall, and Atmospheric Conditions on Summertime Convective Storm Initiation under Weak Synoptic-Scale Forcing
Authors: Tracy Christopher , Mecikalski John R. 
Published: October 2023

Abstract
Throughout the summer months in the Southeast United States (SEUS), the initiation of isolated convection (CI) can occur abundantly during the daytime with weak synoptic support (e.g., weak wind shear). Centered around this premise, a dual-summer, limited-area case study of CI events concerning both geographical and meteorological features was conducted. The goal of this study was to help explain SEUS summertime CI in weak synoptic environments, which can enhance CI predictability. Results show that spatial CI nonrandomness event patterns arise, with greater CI event density appearing over high elevation by midday. Later in the day, overall CI event counts subside with other mechanisms/factors emerging (e.g., urban heat island). Antecedent rainfall, instability, and moisture features are also higher on average where CI occurred. In a random forest feature importance analysis, elevation was the most important variable in dictating CI events in the early to midafternoon while antecedent rainfall and wind direction consistently rank highest in permutation importance. The results cumulatively allude to, albeit in a muted, nonsignificant statistical signal, and a degree of spatial clustering of CI event occurrences cross the study domain as a function of daytime heating and contributions of features to enhancing CI probabilities (e.g., differential heating and mesoscale thermal circulations).

Significance Statement
Widespread isolated thunderstorms in the Southeast United States summer season with weak synoptic support have been commonly observed. With forecasting these remaining a challenge, a dual-summer intercomparison of geographical/meteorological features with convective initiation events was conducted. Radar data with a minimum threshold for convective initiation detection (35 dBZ) were used. Spatial nonrandomness was discovered with greater event density appearing over higher elevation by midday. Features such as prior rainfall and atmospheric instability/moisture were higher on average where initiation occurred. In a feature importance analysis, elevation ranked higher in the early to midafternoon hours while antecedent rainfall and wind direction ranked highest overall in permutation importance. These results allude to the contribution of localized phenomena to the nonrandomness (e.g., mesoscale circulations).
Treatment of active systemic lupus erythematosus with baricitinib: A meta-analysis of randomized controlled trials
Authors: Lee Young Ho , Song Gwan Gyu 
Published: October 2023

Objective This study aimed to evaluate the safety and effectiveness of baricitinib in patients with systemic lupus erythematosus (SLE). Methods We searched MEDLINE, EMBASE, and the Cochrane Controlled Trials Register to find relevant publications. Using data from randomized controlled trials (RCTs), we performed a meta-analysis to investigate the safety and efficacy of baricitinib in patients with active SLE who did not respond well to standard treatments. Results A total of 1849 individuals (1235 experimental participants and 614 controls) from three RCTs on baricitinib were included. A reduction of ≥ 4 points from baseline in SLEDAI-2K score in the baricitinib 4 mg group was greater than the placebo group’s reduction (odds ratio [OR] = 1.407, 95% confidence interval [CI] 1.123–1.763, p = .003). The baricitinib 4 mg group significantly outperformed the placebo group in terms of SLEDAI-2K remission of arthritis or rash (OR = 1.327, 95% CI = 1.059–1.663, p = .014). Other effectiveness outcomes such as the SRI4 response did not substantially improve in the baricitinib 4 mg group when compared with the placebo group. And there were no significant increase in the efficacy outcomes in the baricitinib 2 mg group than in the placebo group. However, there was a substantially higher incidence of severe adverse events (SAE) and serious infections in the baricitinib 4 mg group (OR = 1.493, 95% CI = 1.002–2.225, p = .049; OR = 2.303, 95% CI = 1.147–4.622, p = .019) compared to the placebo group. There were no differences between the baricitinib 2 mg and placebo groups in any of the safety outcome data. Conclusion Meta-analysis reveals that baricitinib 4 mg is beneficial for treating active SLE in terms of a reduction of ≥ 4 points from baseline in SLEDAI-2K score and SLEDAI-2K remission of arthritis or rash. However, the higher frequency of SAEs and serious infections was observed in the group receiving baricitinib 4 mg.
‘It must be right, I saw it on TV!’: An observational study of third stage birth practices in popular television programmes
Authors: Dawda Gati , Weeks Andrew D , Bewley Susan 
Published: October 2023

Objectives To examine modern media depictions of the third stage of birth in a selection of UK television representations. Design Observational study of a sample of televised fictional and real births, audited against current National Institute of Health and Social Care Excellence (NICE) guidance. Setting UK television channels BBC ( Call The Midwife and This Is Going To Hurt) and Channel 4 ( One Born Every Minute). Participants 87 births from 48 episodes, sampled from the three shows. Main outcome measures The primary outcome was the number of births where the cord was clamped at more than 1 min after birth. Secondary outcomes included place and type of birth, measures of dignity and paternal involvement. Results Overall, the timing of cord clamping was clearly shown in 25/87 (29%) of births, of which only 4/25 (16%) occurred at more than 1 min in screen time. The place of birth and caesarean section (CS) rate changed according to the series perspective and era; graphic explicit images were shown, but these related to CS detail. Conclusions UK television shows have accurately depicted changes in place, culture and type of birth over the last century. They provide the public with a view of new rituals but an inaccurate picture of good quality care. Early cord clamping was shown in most births, even those set after 2014. No programme informed viewers about the safety aspects. When showing outdated practices, broadcasters have a public health duty to inform viewers that this is no longer recommended.
Macrophage-driven cardiac inflammation and healing: insights from homeostasis and myocardial infarction
Authors: Zuo Wenjie , Sun Renhua , Ji Zhenjun , Ma Genshan 
Published: October 2023

AbstractEarly and prompt reperfusion therapy has markedly improved the survival rates among patients enduring myocardial infarction (MI). Nonetheless, the resulting adverse remodeling and the subsequent onset of heart failure remain formidable clinical management challenges and represent a primary cause of disability in MI patients worldwide. Macrophages play a crucial role in immune system regulation and wield a profound influence over the inflammatory repair process following MI, thereby dictating the degree of myocardial injury and the subsequent pathological remodeling. Despite numerous previous biological studies that established the classical polarization model for macrophages, classifying them as either M1 pro-inflammatory or M2 pro-reparative macrophages, this simplistic categorization falls short of meeting the precision medicine standards, hindering the translational advancement of clinical research. Recently, advances in single-cell sequencing technology have facilitated a more profound exploration of macrophage heterogeneity and plasticity, opening avenues for the development of targeted interventions to address macrophage-related factors in the aftermath of MI. In this review, we provide a summary of macrophage origins, tissue distribution, classification, and surface markers. Furthermore, we delve into the multifaceted roles of macrophages in maintaining cardiac homeostasis and regulating inflammation during the post-MI period.
Cross-tissue patterns of DNA hypomethylation reveal genetically distinct histories of cell development
Authors: Scott Timothy J. , Hansen Tyler J. , McArthur Evonne , Hodges Emily 
Published: October 2023

Abstract
Background
Establishment of DNA methylation (DNAme) patterns is essential for balanced multi-lineage cellular differentiation, but exactly how these patterns drive cellular phenotypes is unclear. While > 80% of CpG sites are stably methylated, tens of thousands of discrete CpG loci form hypomethylated regions (HMRs). Because they lack DNAme, HMRs are considered transcriptionally permissive, but not all HMRs actively regulate genes. Unlike promoter HMRs, a subset of non-coding HMRs is cell type-specific and enriched for tissue-specific gene regulatory functions. Our data further argues not only that HMR establishment is an important step in enforcing cell identity, but also that cross-cell type and spatial HMR patterns are functionally informative of gene regulation.

Results
To understand the significance of non-coding HMRs, we systematically dissected HMR patterns across diverse human cell types and developmental timepoints, including embryonic, fetal, and adult tissues. Unsupervised clustering of 126,104 distinct HMRs revealed that levels of HMR specificity reflects a developmental hierarchy supported by enrichment of stage-specific transcription factors and gene ontologies. Using a pseudo-time course of development from embryonic stem cells to adult stem and mature hematopoietic cells, we find that most HMRs observed in differentiated cells (~ 60%) are established at early developmental stages and accumulate as development progresses. HMRs that arise during differentiation frequently (~ 35%) establish near existing HMRs (≤ 6 kb away), leading to the formation of HMR clusters associated with stronger enhancer activity. Using SNP-based partitioned heritability from GWAS summary statistics across diverse traits and clinical lab values, we discovered that genetic contribution to trait heritability is enriched within HMRs. Moreover, the contribution of heritability to cell-relevant traits increases with both increasing HMR specificity and HMR clustering, supporting the role of distinct HMR subsets in regulating normal cell function.

Conclusions
Our results demonstrate that the entire HMR repertoire within a cell-type, rather than just the cell type-specific HMRs, stores information that is key to understanding and predicting cellular phenotypes. Ultimately, these data provide novel insights into how DNA hypo-methylation provides genetically distinct historical records of a cell’s journey through development, highlighting HMRs as functionally distinct from other epigenomic annotations.
The energy metabolism of Balantidium polyvacuolum inhabiting the hindgut of Xenocypris davidi
Authors: Bu Xia-lian , Zhao Wei-shan , Li Zhong-yang , Ma Hong-wei , Chen Yu-shun , Li Wen-xiang , Zou Hong , Li Ming , Wang Gui-tang 
Published: October 2023

AbstractAnaerobic parasitic ciliates are a specialized group of ciliates that are adapted to anoxic and oxygen-depleted habitats. Among them, Balantidium polyvacuolum, which inhabits the hindgut of Xenocyprinae fishes, has received very limited scientific attention, so the molecular mechanism of its adaptation to the digestive tract microenvironment is still unclear. In this study, transmission electron microscopy (TEM) and single-cell transcriptome analysis were used to uncover the metabolism of B. polyvacuolum. Starch granules, endosymbiotic bacteria, and multiple specialized mitochondrion-related organelles (MROs) of various shapes were observed. The MROs may have completely lost the electron transport chain (ETC) complexes I, III, IV, and V and only retained succinate dehydrogenase subunit A (SDHA) of complex II. The tricarboxylic acid (TCA) cycle was also incomplete. It can be inferred that the hypoxic intestinal environment has led to the specialization of the mitochondria in B. polyvacuolum. Moreover, carbohydrate-active enzymes (CAZymes), including carbohydrate esterases, enzymes with a carbohydrate-binding module, glycoside hydrolases, and glycosyltransferases, were identified, which may constitute evidence that B. polyvacuolum is able to digest carbohydrates and starch. These findings can improve our knowledge of the energy metabolism and adaptive mechanisms of B. polyvacuolum.
Online commercial sex-seeking among female sex workers in south China: a cross-sectional study
Authors: Zhao Peizhen , Xu Wenqian , Ye Rouxuan , Shi Yijia , Wang Cheng 
Published: October 2023

Abstract
Background
Online communication platforms have the potential to facilitate commercial sex among female sex workers (FSW), increasing the risk of contracting sexually transmitted diseases (STD). This study aimed to describe the patterns of online commercial sex-seeking and examine the associated factors among FSW in China.

Methods
A venue-based cross-sectional study was conducted in five cities in Guangdong Province, China, between April and October 2020. Data on socio-demographic characteristics, sexual behaviors, and online commercial sex-seeking patterns were collected through face-to-face interviews. Venous blood and urine samples were collected for STD testing. Univariate and multivariable logistic regressions were used to explore the factors associated with online commercial sex-seeking.

Results
A total of 1155 FSW were recruited in physical venues for this study. Among them, 33.42% reported ever using online applications to seek commercial sex. The prevalence of HIV, syphilis, gonorrhea, chlamydia, and STD was 0.26%, 1.30%, 4.40%, 15.54%, and 18.39%, respectively, among FSW who had ever used both physical and online venues to seek commercial sex, which was higher than among FSW who had never sought commercial sex online. Multivariable logistic regression indicated that FSW who used online platforms to seek commercial sex were more likely to have STD (adjusted odds ratio (aOR) = 1.48, 95%CI: 1.05–2.09), experience unintended pregnancies due to commercial sex (aOR = 1.78, 95%CI: 1.21–2.62), be diagnosed as infertile (aOR = 3.20, 95%CI: 1.42–7.21), and undergo abortions (aOR = 1.69, 95%CI: 1.29–2.20).

Conclusion
A significant proportion of FSW who practiced in physical venues in China engaged in seeking commercial sex online, and this behavior is positively correlated with both STD and reproductive health outcomes. Given the high prevalence of online sex-seeking, it is crucial to provide a wide range of internet-based healthcare interventions and reproductive health services to Chinese FSW.
Upregulated CANT1 is correlated with poor prognosis in hepatocellular carcinoma
Authors: Liu Ting , Li Zhi-zhao , Sun Lei , Yang Kun , Chen Jia-min , Han Xiao-yi , Qi Li-ming , Zhou Xin-gang , Wang Peng 
Published: October 2023

Abstract
Background
CANT1, as calcium-activated protein nucleotidase 1, is a kind of phosphatase. It is overexpressed in some tumors and related to poor prognosis, but few studies explore its function and carcinogenic mechanism in hepatocellular carcinoma (HCC).

Methods
The expression of CANT1 mRNA and protein was analyzed by the Cancer Genome Atlas (TCGA) database and immunohistochemistry(IHC) staining. The relationship between CANT1 expression and clinicopathology was evaluated by various public databases. The receiver operating characteristic (ROC) curve was used to assess the diagnostic accuracy of CANT1 by the area under curve (AUC). Univariate, multivariate Cox regression and Kaplan-Meier curves were applied to evaluate the predictive value of CANT1 on the prognosis of HCC. Methsurv was used to analyze gene changes and DNA methylation, and its impact on prognosis. The enrichment analysis of DEGs associated with CANT1 revealed the biological process of CANT1 based on Gene Set Enrichment Analysis (GSEA). The relationship between immune cell infiltration level and CANT1 expression in HCC was investigated using the single-sample GSEA (ssGSEA) method and the Tumor Immune Estimation Resource (TIMER) database. Finally, the association between CANT1 and immune checkpoints and drug sensitivity was also analyzed.

Results
CANT1 was highly expressed in 22 cancers, including HCC, and CANT1 overexpression in HCC was confirmed by IHC. The expression of CANT1 was correlated with clinical features, such as histologic grade. Highly expressed CANT1 caused poor overall survival (OS) of HCC patients. Univariate and multivariate regression analysis suggested that CANT1 was an independent prognostic marker. Of the 31 DNA methylation at CpG sites, three CpG sites were associated with the prognosis of HCC. GSEA indicated that CANT1 was mainly involved in the cell cycle, DNA replication, and etc. Moreover, CANT1 expression was correlated with immune cell infiltration and independently associated with the prognosis of HCC patients. Finally, CANT1 expression was correlated with most immune checkpoints and drug sensitivity.

Conclusion
CANT1 may be a latent oncogene of HCC, and associated with immune cells and immune checkpoints, which may assist in HCC treatment.