bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arterial angioembolisation versus pre-peritoneal pelvic packing in haemodynamically unstable patients with complex pelvic fractures: a meta-analysis
Authors: Migliorini Filippo , Cocconi Federico , Schipper Inger , ten Duis Kaj , Marzi Ingo , Komadina Radko , Hildebrand Frank , Wendt Klaus 
Published: November 2023

Abstract
Introduction
Angioembolisation (AE) and/or pre-peritoneal pelvic packing (PPP) may be necessary for patients with complex pelvic fractures who are haemodynamically unstable. However, it remains unclear whether AE or PPP should be performed as an initial intervention and ongoing debates exist. This meta-analysis aimed to compare AE versus PPP in haemodynamically unstable patients with acute pelvic fractures. The primary outcomes of interest were to compare in-hospital mortality rate and number of blood units transfused. Secondary outcomes included evaluating differences in the time from diagnosis to treatment, as well as the length of stay in the intensive care unit (ICU) and hospital.

Methods
All clinically relevant studies comparing AE versus PPP in patients with complex pelvic fractures and haemodynamic instability were accessed. The 2020 PRISMA guidelines were followed. In September 2023, the following databases were accessed: PubMed, Web of Science, Google Scholar and Embase, without constraint.

Results
Data from 320 patients were collected (AE: 174; PPP: 146). The mean age on admission was 47.4 ± 7.2 years. The mean Injury Severity Score (ISS) on admission was 43.5 + 5.4 points. Baseline comparability was observed in ISS (P = 0.5, Table 3) and mean age (P = 0.7, Table 3). No difference was reported in mortality rate (P = 0.2) or rate of blood units transfused (P = 0.3). AE had a longer mean time to the procedure of 44.6 min compared to PPP (P = 0.04). The mean length of ICU and hospital stay were similar in both groups.

Conclusion
Despite the longer mean time from admission to the procedure, no significant differences were found between AE and PPP in terms of in-hospital mortality, blood units transfused, or length of ICU, and hospital stay. These findings should be interpreted considering the limitations of the present study. High-quality comparative research is strongly warranted.

Level of evidence
Level IV, meta-analysis.
Atmospheric response to seasonal changes in sea surface temperature during the boreal summer in the Tropical Atlantic
Authors: Wane Dahirou , Coëtlogon Gaëlle de , Lazar Alban , Wade Malick , Gaye Amadou T. 
Published: November 2023

AbstractWe investigate the atmospheric response to seasonal variations in sea surface temperature (SST) in the eastern tropical Atlantic during the boreal summer, using the Weather Research and Forecasting (WRF) regional atmospheric model. Three ensembles of 11 simulations each are produced with different SST forcings: the control ensemble (CTL) uses the observed climatology of the SST in 2000–2009, while the Frozen North (FzN) and Frozen South (FzS) experiments block the seasonal warming or cooling of the SST from June onwards in a region confined to the eastern tropical Atlantic. The result is a cold SST anomaly in the northeastern tropical Atlantic off the coasts of Senegal and Mauritania in FzN, and a warm anomaly in the southeastern region (Gulf of Guinea and the cold tongue zone in the equatorial Atlantic) in FzS. Comparison with CTL reveals significant impacts of these SST anomalies on the position and intensity of the marine intertropical convergence zone (ITCZ) and on West African rainfall during July and August. Over the ocean, the cold anomaly in NETA suppresses convection on the northern side of the ITCZ (north of 10$$^\circ$$

∘

N), while the warm anomaly in the Gulf of Guinea strengthens convection on its southern flank. The latter is also leading to a sharp increase in precipitation in the coastal regions to the northeast of the Gulf of Guinea. These changes are clearly due to variations in surface pressure gradients and the divergence of low-level moisture in response to SST anomalies, which in turn induce changes in deep atmospheric convection through thermodynamic feedback. On the continent, a substantial reduction in precipitation is observed in the western Sahel (particularly Senegal) following the cold anomaly in NETA, and in the eastern Sahel following the warm anomaly in the Gulf of Guinea: both are explained by a positive anomaly in the divergence of moisture transport in the upper troposphere, associated with an acceleration of the African easterly jet along its southern edge. However, the mechanism by which the SST anomalies create this acceleration in both experiments remains to be elucidated.
The increased lateral tibial slope may result in inferior long-term clinical outcome after DB-ACL reconstruction
Authors: Yang Cheng-Pang , Hung Shih-Feng , Lin Keng-Yi , Hung Yu-Chieh , Chen Yi-Jou , Yao Shang-Yu , Chiu Chih-Hao , Chan Yi-Sheng 
Published: November 2023

Abstract
Purpose
To determine if there is a correlation between lateral tibial slope and long-term clinical results in patients who underwent double-bundle ACL reconstruction.

Methods
We retrospectively reviewed patients that received double-bundle ACL reconstruction at a single institution by a single surgeon from January 2011 to December 2014. All the magnetic resonance imaging were reviewed and lateral tibial slopes (LTS) were recorded by an experienced surgeon and rechecked by the other two authors of this study that specialized in orthopedic knee surgery. The relationship between PROMs measurement and lateral tibial slope were analyzed. The patients were then separated into two groups (LTS > 7.4° and < 7.4°) according to the previous study.

Results
A total of 119 patients were enrolled in this study. All enrolled patients were followed for at least 8 years. The PROMS result were negatively correlated with the lateral tibial slope (p values all < 0.001). The patients with high lateral tibial slope had significantly lower PROMS values (Lysholm 94.26 ± 5.61 vs 80.15 ± 8.28, p = 0.013; IKDC 82.99 ± 4.55 vs 70.09 ± 7.15, p = 0.003; Tegner 9.32 ± 0.95 vs 6.85 ± 1.99, p < 0.001). Finally, the LTS cutoff value between patients with “Good” and “Fair” Lysholm score in our study was 7.55 degrees.

Conclusions
Patients with high lateral tibial slope may result in inferior long-term subjective outcomes. The using of double-bundle ACL reconstruction along cannot overcome the negative impact caused by steep lateral tibial slope. A lateral tibial slope of 7.55° may be used as a cut-off for a good clinical outcome.

Level of evidence
III retrospective comparative prognostic trial.
Recurrent Cough in the Elderly: A Forgotten Entity
Authors: Kaulamo Johanna Tuulikki , Lätti Anne Marika , Koskela Heikki Olavi 
Published: November 2023

Abstract
Introduction
Recurrent cough is little researched in adults. We investigated the prevalence, risk factors, and consequences of recurrent cough, and compared the results to those of isolated chronic cough.

Methods
Cross-sectional email survey in an elderly community-based population. Recurrent cough was defined as ≥ 3 cough episodes within one year (each lasting ≥ 1 week) and no current chronic cough. Isolated chronic cough was defined as current cough lasting ≥ 8 weeks and no recurrent cough.

Results
The prevalence of recurrent cough was 3.8% among all respondents (n = 5983). Recurrent cough was associated with asthma (aOR 3.32 (95% CI 2.13–5.18)), chronic rhinosinusitis (2.91 (1.89–4.46)), family history of chronic cough (2.59 (1.88–3.56)), analgesic intolerance (2.13 (1.27–3.57)), male gender (1.92 (1.39–2.66)), gastro-esophageal reflux disease (1.73 (1.21–2.47)), obstructive sleep apnoea (1.69 (1.23–2.32)), symptom sum (1.12 per symptom (1.03–1.22)), and younger age (0.96 per year (0.93–1.00)).
Isolated chronic cough was associated with chronic rhinosinusitis (3.45 (2.39–4.97)), asthma (2.17 (1.38–3.41), gastro-esophageal reflux disease (1.80 (1.32–2.47)), family history of chronic cough (1.80 (1.35–2.41)), obstructive sleep apnoea (1.49 (1.12–2.00)), symptom sum (1.18 per symptom (1.10–1.27)), and body mass index (0.96 per unit (0.93–1.00)).
Among subjects with recurrent and isolated chronic cough, the prevalence of depressive symptoms were 7.7% and 4.2%, p = 0.11, the Leicester Cough Questionnaire total scores 15.2 (14.6–15.8) and 16.3 (16.0–16.6), P = 0.001, and the mean number of yearly cough-related doctor`s visits 0.58 (0.45–0.71) and 0.36 (0.19–0.53), P = 0.007, respectively.

Conclusion
The risk factors and consequences of recurrent and isolated chronic cough were comparable. Recurrent cough seems beneficial to address in cough evaluation.
Independent, additive and interactive effects of acute normobaric hypoxia and cold on submaximal and maximal endurance exercise
Authors: Callovini A. , Fornasiero A. , Savoldelli A. , Decet M. , Skafidas S. , Pellegrini B. , Bortolan L. , Schena F. 
Published: November 2023

Abstract
Purpose
To evaluate the independent and combined effects of hypoxia (FiO2 = 13.5%) and cold (− 20 °C) on physiological and perceptual responses to endurance exercise.

Methods
14 trained male subjects ($$\mathop {\text{V}}\limits^{.}$$

V
.

O2max: 64 ± 5 mL/kg/min) randomly performed a discontinuous maximal incremental test to exhaustion on a motorized treadmill under four environmental conditions: Normothermic-Normoxia (N), Normothermic-Hypoxia (H), Cold-Normoxia (C) and Cold-Hypoxia (CH). Performance and physiological and perceptual responses throughout exercise were evaluated.

Results
Maximal WorkLoad (WL) and WL at lactate threshold (LT) were reduced in C (− 2.3% and − 3.5%) and H (− 18.0% and − 21.7%) compared to N, with no interactive (p = 0.25 and 0.81) but additive effect in CH (− 21.5% and − 24.6%). Similarly, HRmax and Vemax were reduced in C (− 3.2% and − 14.6%) and H (− 5.0% and − 7%), showing additive effects in CH (− 7.7% and − 16.6%). At LT, additive effect of C (− 2.8%) and H (− 3.8%) on HR reduction in CH (− 5.7%) was maintained, whereas an interactive effect (p = 0.007) of the two stressors combined was noted on Ve (C: − 3.1%, H: + 5.5%, CH: − 10.9%). [La] curve shifted on the left in CH, displaying an interaction effect between the 2 stressors on this parameter. Finally, RPE at LT was exclusively reduced by hypoxia (p < 0.001), whereas TSmax is synergistically reduced by cold and hypoxia (interaction p = 0.047).

Conclusion
If compared to single stress exposure, exercise performance and physiological and perceptual variables undergo additive or synergistic effects when cold and hypoxia are combined. These results provide new insight into human physiological responses to extreme environments.
Safety of electroconvulsive therapy (ECT) in pregnancy: a systematic review of case reports and case series
Authors: Cipolla Salvatore , Catapano Pierluigi , Messina Martin , Pezzella Pasquale , Giordano Giulia Maria 
Published: November 2023

AbstractPregnancy and the immediate postpartum period are considered at high risk for women who have already received a previous psychiatric diagnosis and might represent a stressful event favoring the onset of new psychiatric disorders. The electroconvulsive therapy (ECT) is effective for the treatment of severe, treatment-resistant mental disorders, and it could represent a therapeutic choice for psychiatric conditions during pregnancy. The purpose of this systematic review is to evaluate the safety of ECT during pregnancy and to update the state of the art of its use. An extensive literature search on PubMed, APA PsycInfo, and Scopus databases for relevant articles published from inception to September 2023 has been performed. A final number of 45 articles (34 case reports and 11 case series, for a total of 130 pregnant women) were included in the present review. The limited evidence confirmed that ECT is effective in determining a partial remission of symptoms in women suffering from severe mental disorders, especially in the presence of suicidal ideation or psychosis, during all pregnancy epochs. However, ECT is not free from side effects, although the majority of possible complications were of low- or moderate-grade and not life-threatening for the women. Exposure to pharmacological treatment before or during the ECT or to the anesthetic during ECT might have contributed to the onset of these complications. ECT techniques evolved over years, increasing the degree of its safety, and according to our review it appears to be relatively safe and effective during pregnancy in the majority of cases.
F-IVM: analytics over relational databases under updates
Authors: Kara Ahmet , Nikolic Milos , Olteanu Dan , Zhang Haozhe 
Published: November 2023

AbstractThis article describes F-IVM, a unified approach for maintaining analytics over changing relational data. We exemplify its versatility in four disciplines: processing queries with group-by aggregates and joins; learning linear regression models using the covariance matrix of the input features; building Chow-Liu trees using pairwise mutual information of the input features; and matrix chain multiplication. F-IVM has three main ingredients: higher-order incremental view maintenance; factorized computation; and ring abstraction. F-IVM reduces the maintenance of a task to that of a hierarchy of simple views. Such views are functions mapping keys, which are tuples of input values, to payloads, which are elements from a ring. F-IVM supports efficient factorized computation over keys, payloads, and updates. It treats uniformly seemingly disparate tasks: While in the key space, all tasks require general joins and variable marginalization, in the payload space, tasks differ in the definition of the sum and product ring operations. We implemented F-IVM on top of DBToaster and show that it can outperform classical first-order and fully recursive higher-order incremental view maintenance by orders of magnitude while using less memory.
Farmers’ behavioural determinants of on-farm biodiversity management in Europe: a systematic review
Authors: Klebl Fabian , Feindt Peter H. , Piorr Annette 
Published: November 2023

AbstractAgricultural intensification and landscape homogenisation are major drivers of biodiversity loss in European agricultural landscapes. Improvements require changes in farming practices, but empirical evidence on farmers’ motivations underlying their on-farm biodiversity management remains fragmented. To date, there is no aggregated overview of behavioural determinants that influence European farmers’ decisions to implement biodiversity-friendly farming practices. This study aims to fill this knowledge gap by conducting a systematic literature review of 150 empirical studies published between 2000 and 2022. We identified 108 potential determinants of farmers’ behaviour, which were integrated into a multilevel framework. The results show that the farmers’ decisions are complex and often non-directional processes, shaped by numerous external (at a society, landscape, community, and farm level) and internal factors. These factors are embedded in regional and cultural contexts. However, the analysis of study sites indicates that the spatial coverage of scientific evidence on biodiversity-friendly farming measures is uneven across Europe. Given the diversity of local and socio-cultural conditions, there is a need for public policies, including the European Union’s Common Agricultural Policy, to address more specifically determinants encouraging biodiversity-friendly farm management. This entails reflecting culture-specific perspectives and incorporating experiential knowledge into multilevel policy design processes, as well as offering regionally adapted advice on measure implementation and biodiversity impacts.
Herbivores influence biogeochemical processes by altering litter quality and quantity in a subarctic wetland
Authors: Saunders Taylor , Adkins Jaron , Beard Karen H. , Atwood Trisha B. , Waring Bonnie G. 
Published: November 2023

AbstractGlobal change drivers that modify the quality and quantity of litter inputs to soil affect greenhouse gas fluxes, and thereby constitute a feedback to climate change. Carbon cycling in the Yukon–Kuskokwim (Y–K) River Delta, a subarctic wetland system, is influenced by landscape variations in litter quality and quantity generated by herbivores (migratory birds) that create ‘grazing lawns’ of short stature, nitrogen-rich vegetation. To identify the mechanisms by which these changes in litter inputs affect soil carbon balance, we independently manipulated qualities and quantities of litter representative of levels found in the Y–K Delta in a fully factorial microcosm experiment. We measured CO2 fluxes from these microcosms weekly. To help us identify how litter inputs influenced greenhouse gas fluxes, we sequenced soil fungal and bacterial communities, and measured soil microbial biomass carbon, dissolved carbon, inorganic nitrogen, and enzyme activity. We found that positive correlations between litter input quantity and CO2 flux were dependent upon litter type, due to differences in litter stoichiometry and changes to the structure of decomposer communities, especially the soil fungi. These community shifts were particularly pronounced when litter was added in the form of herbivore feces, and in litter input treatments that induced nitrogen limitation (i.e., senesced litter). The sensitivity of carbon cycling to litter quality and quantity in this system demonstrates that herbivores can strongly impact greenhouse gas fluxes through their influence on plant growth and tissue chemistry.
Graphical abstract
A memetic NSGA-II for the multi-objective flexible job shop scheduling problem with real-time energy tariffs
Authors: Burmeister Sascha Christian , Guericke Daniela , Schryen Guido 
Published: November 2023

AbstractRising costs for energy are increasingly becoming a vital factor for the production planning of manufacturing companies. Manufacturers face the challenge to react to dynamic energy prices and design energy cost efficient schedules in their production planning. In the literature, the energy cost-aware Flexible Job Shop Scheduling Problem addresses minimization of both makespan and energy costs. Recent studies provide multi-objective approaches to model the trade-off of minimizing makespan and energy costs. However, the literature is limited to coarse-grained time periods and does not consider dynamic tariffs where costs change at short intervals, so that production schedules may fall short on energy costs. We aim to close this research gap by considering frequently changing real-time energy tariffs. We propose a multi-objective memetic algorithm based on the non-dominated sorting genetic algorithm (NSGA-II) with both makespan and energy cost minimization as the objectives. We evaluate our approach by conducting computational experiments using prominent FJSP-benchmark instances from the literature, which we supplement with empiric dynamic energy prices. We show results on method performance and compare the memetic NSGA-II with the results of an exact state-of-the-art solver. To investigate the trade-off between a short makespan and low energy costs, we present solutions on the approximated Pareto front and discuss our results.
High-resolution PGT-A results in incidental identification of patients with small pathogenic copy number variants
Authors: Leahy Deirdre , Marin Diego , Xu Jia , Eccles Jennifer , Treff Nathan R. 
Published: November 2023

Abstract
Purpose
This study aimed to evaluate whether a high-throughput high-resolution PGT-A method can detect copy number variants (CNVs) that could have clinical implications for patients and their embryos.

Methods
A prospective analysis of PGT-A cases was conducted using a high-resolution SNP microarray platform with over 820,000 probes. Cases where multiple embryos possessed the same segmental imbalance were identified, and preliminary PGT-A reports were issued recommending either parental microarray or conventional karyotyping to identify CNVs or translocations.

Results
Analysis of 6080 sequential PGT-A cases led to identification of 41 cases in which incidental findings were observed (0.7%) and parental testing was recommended. All cases, in which parental studies were completed, confirmed the original PGT-A incidental findings. In 2 of the cases, parental studies indicated a pathogenic variant with clinical implications for the associated embryos. In one of these cases, the patient was identified as a carrier of a duplication in chromosome 15q11.2:q11.2 (SNRPN + +), which is associated with autism spectrum disorder. In the second case, the patient was heterozygous positive for an interstitial deletion of 3p26.1:p26.3, which is associated with 3p deletion syndrome and had clinical implications for the patient and associated embryos. In each case, parental studies were concordant with PGT-A findings and revealed the presence of an otherwise unknown CNV.

Conclusion
High-throughput high-resolution SNP array–based PGT-A has the ability to detect previously unknown and clinically significant parental deletions, duplications, and translocations. The use of cost-effective SNP array–based PGT-A methods may improve the effectiveness of PGT by identifying and preventing previously unknown pathogenic CNVs in children born to patients seeking in vitro fertilization.
Novel Interaction Control in Adolescent Idiopathic Scoliosis Treatment Using a Robotic Brace
Authors: Farhadiyadkuri Farhad , Zhang Xuping 
Published: November 2023

AbstractAdolescent Idiopathic Scoliosis (AIS) may affect the quality of the patient’s life if it is left untreated. Bracing is prescribed to halt or reduce the curvature progression and avoid surgery. However, the in-brace correction pressure remains unclear, and it is controlled passively by tightening/losing the brace’s strap. Computational modeling has recently attracted researchers’ attention to predict and optimize the AIS bracing treatment. In this paper, a Multi Body-Finite Element (MB-FE) Simscape model and an analytical model of the AIS bracing treatment are created. The MB-FE Simscape model is used to predict the in-brace correction pressure. Furthermore, a Novel Position-based Impedance Control (NPIC) is proposed to control the dynamic interaction between the robotic brace and torso. In this method, the error between the desired and estimated impedance parameters is involved in the controller design to improve the performance of the typical PIC in terms of pose tracking and impedance model tracking. In-vivo data from the literature and numerical simulations are used to validate the MB-FE Simscape model and analytical model. The performance of the proposed controller is verified using numerical simulations in terms of pose tracking and impedance model tracking.
Durable and Low-Cost Chitosan Decorated Fe/MOF-5 Bimetallic MOF Composite Film for High Performance of the Congo Red Adsorption
Authors: Abd El-Monaem Eman M. , Omer Ahmed M. , Eltaweil Abdelazeem S. 
Published: November 2023

AbstractThe auspicious merits of polysaccharides make them eminent choices in numerous fields, particularly water remediation. Nonetheless, polysaccharides like chitosan (CTS) suffer from low adsorbability. Meanwhile, the recent revolution in material science has produced substances with supreme adsorbability, such as metal-organic frameworks (MOFs). Consequently, the Fe/MOF-5@CTS composite film was synthesized by doping a low amount (5 wt%) of Fe/MOF-5 into the CTS film. The crystallinity, morphology, composition, and surface charge of the Fe/MOF-5@CTS composite film were identified using multiple characterization analyses. Furthermore, the adsorption property of Fe/MOF-5@CTS was examined for the removal of Congo red (CR). Surprisingly, the Qmax of CR onto Fe/MOF-5@CTS reached 219.78 mg/g. Additionally, the composite film only lost 18.54% of its capacity after ten cycles. The selectivity test demonstrated the higher selectivity of the positively charged-rich composite film towards anionic dyes, especially CR, compared to the cationic dyes. Based on the practical experiments and analysis tools, the adsorption mechanism of CR onto Fe/MOF-5@CTS is presumed to occur via electrostatic, host-guest, π-π interaction, and coordination bonds.