bluuebunny/crossref_metadata_2025_split huggingface dataset:
ICT Standards in Smart Grid Projects – Between a Standard’s Intended and Factual Role in Complex Technological Developments
Authors: Paustian Sabrina , Mattes Jannika 
Published: February 2024

AbstractDigital technologies such as smart grids are associated with new challenges for organizations as both technological and social heterogeneity increase. ICT standards play a crucial role in coping with this growing heterogeneity. However, we have little insight into precisely how ICT standards unfold in innovation projects. Compared to ‘ordinary’ standards, it would be expected that they are more pervasive and binding. However, ICT standards also need to be adopted into formal, corporate rules and be further interpreted and drawn upon in informal routines. This actual implementation, the dealing with inconsistencies and contradictions and if the ICT standard is being conceived as binding, is revealed in day-to-day practices. Conceptually, we differentiate between the formal and informal adoption of the standard and for both cases consider the dimensionsdecision programs,communication channelsandpersonnel. We empirically investigate the adoption of one ICT standard, the Use Case Methodology (UCM), in a qualitative case study of a smart grid project. Our findings illustrate how the formal implementation of the UCM succeeds while the informal reliance upon this standard is far less pronounced. In this way, ICT standards differ less from ‘ordinary’ standards than might have been expected.
Evaluation of cardiac electrophysiological features in patients with premature adrenarche
Authors: Ertaş Kerem , Gül Özlem , Yıldırım Ruken , Özalkak Şervan 
Published: February 2024

Abstract

Objectives
This study aimed to analyze the cardiac effects of hyperandrogenism in premature adrenarche (PA) and evaluate the risk of arrhythmia development.

Methods
Fifty patients with PA and 50 healthy children from a pediatric endocrinology outpatient clinic were included in the study. The patients underwent echocardiography and electrocardiographic evaluations. Conventional echocardiography, tissue Doppler echocardiography, repolarization time, and repolarization dispersion time were evaluated.

Results
The median age in the PA and control groups was 7.91 years (5.83–9.25), 8.08 years (5.75–9.33), respectively. Thirty percent of patients in the PA group were male. While mitral early diastolic velocity deceleration time (DT), isovolumetric relaxation time (IRT), and E/e’ ratio were significantly higher in the PA group than in the control group, mitral lateral annulus tissue Doppler early diastolic velocity was significantly lower (p=0.0001, 0.0001, 0.003, 0.0001). While P wave dispersion (PWD), Tpe, and QT-dispersion (QT-d) values were significantly higher in the PA group than in the control group, the P minimum value was significantly lower in the PA group (p=0.0001, 0.02, 0.004, and 0.0001, respectively).

Conclusions
Early subclinical diastolic dysfunction was observed in the PA group. There was an increased risk of atrial arrhythmia with PWD and an increased risk of ventricular arrhythmia with increased Tpe and QT-d. There was a correlation between testosterone levels and diastolic function parameters. The increased risk of atrial arrhythmia is closely related to diastolic function.
Numerical study on aerodynamic performance of an intake duct affected by ground effect
Authors: Shi Yalin , Chen Lingling , Chen Pengfei , Yang Qingzhen , Shi Yongqiang , Yang Hua 
Published: February 2024

Abstract
This paper numerically studied the aerodynamic performance of an intake duct affected by the ground effect on a mobile test bench. The simulations were conducted under no wind and headwind conditions. The time evolution of the ground effect indicates that the coherent structure of the vortex system is mainly composed of the ground vortex, the horse-shoe vortex, and the creeping vortex under no wind condition. And it is mainly composed of the ground vortex, the trailing vortex, and the creeping vortex under headwind condition. Compared to the results under no wind condition, the integral vorticity of the ground vortex is larger than that under the headwind condition. The difference of the total pressure recovery coefficient is small, and the total pressure distortion index is large. The results show that with the decrease of the velocity at the intake duct outlet, the intensity of the ground vortex decreases, and the total pressure recovery coefficient at the intake duct outlet increases.
The N-terminal modification of HORMAD2 causes its ectopic persistence on synapsed chromosomes without meiotic blockade
Authors: Cossu Isabella G , Leu N Adrian , Guan Yongjuan , Wang P Jeremy 
Published: February 2024

In brief
The dissociation of HORMA domain protein 2 (HORMAD2) from the synaptonemal complex is tightly regulated. This study reveals that the N-terminal region of HORMAD2 is critical for its dissociation from synapsed meiotic chromosomes.

Abstract
During meiosis, homologous chromosomes undergo synapsis and recombination. HORMA domain proteins regulate key processes in meiosis. Mammalian HORMAD1 and HORMAD2 localize to unsynapsed chromosome axes but are removed upon synapsis by the TRIP13 AAA+ ATPase. TRIP13 engages the N-terminal region of HORMA domain proteins to induce an open conformation, resulting in the disassembly of protein complexes. Here, we report introduction of a 3×FLAG-HA tag to the N-terminus of HORMAD2 in mice. Coimmunoprecipitation coupled with mass spectrometry identified HORMAD1 and SYCP2 as HORMAD2-associated proteins in the testis. Unexpectedly, the N-terminal tagging of HORMAD2 resulted in its abnormal persistence along synapsed regions in pachynema and ectopic localization to telomeres in diplonema. Super-resolution microscopy revealed that 3×FLAG-HA-HORMAD2 was distributed along the central region of the synaptonemal complex, whereas wild-type HORMAD1 persisted along the lateral elements in 3×FLAG-HA-HORMAD2 meiocytes. Although homozygous mice completed meiosis and were fertile, homozygous males exhibited a significant reduction in sperm count. Collectively, these results suggest that the N-terminus of HORMAD2 is important for its timely removal from meiotic chromosome axes.
The Characteristics of Pineapple Probiotic Drinks Enriched by Inulin’s Mangrove
Authors: Pramono Yoyok Budi , Mulyani Sri , Legowo Anang M , Al-Baarri Ahmad Ni’matullah , Bernadine Nathania Maula , Kusuma Daniella Olivia Afri 
Published: February 2024

Probiotic drinks are functional drinks made from the fermentation process of Lactic Acid Bacteria (LAB). This drink usually uses milk-based ingridients, but diversification of vegetable-based products is carried out with pineapple because it contains sugar, vitamin, and has an attractive color and aroma. The probiotic drink was enriched by Inulin's mangrove apple. The research aims to determine the Characteristics of pineapple probiotic drink enriched by inulin's mangrove apple. The research procedures carried out were making pineapple juice, inulin's mangrove apple, and pineapple fruit probiotic drink which enriched by inulin's mangrove apple. The concentration of Inulin's mangrove apple was significant (p<0.05) on the characteristics of pineapple fruit probiotic drinks. The pH valus of 3.70-4.10, total sugar 9.30-10.53o brix, and total LAB 9.5 x 107 -4.33x 108 CFU/mL. There was a significant effect (p<0.05) on the aroma, taste and overall variables in the hedonic test results and no significant effect on the color. THe concentration of 3% inulin's mangrove apple is the best.
Modern Challenges of Event Tourism and Business, Organizational Needs
Authors: Surmanidze Megi 
Published: February 2024

Event tourism is one of the growing and high-income directions of the tourism industry, event tourism is characterized by a variety of content, function and purpose, events that are held around the world have a high social, economic, cultural, historical, sports, business industrial significance. The mentioned article analyzes the course of event tourism, its scope and organizational needs and the relevance of event management. The method of literature review is used for the research. The article discusses the social positive and negative effects of event tourism on the environment, economy and society, as well as the social role in the process of employment and labor market formation. Event management, which is systematically used in event tourism, is new compared to other tourism sectors and is constantly experiencing progress along with the increased demand and need. The research showed that the most important problematic aspect in the process of planning and conducting events is the lack of professional staff and the absence of necessary competencies. Also, the research found that time management is a problem, The respondents have different attitudes towards the digital systems of budgeting, registration and identification of events.
Behavioral Public Administration (BPA): The Need for a New Field (Literature Review)
Authors: Dzidziguri Gvantsa 
Published: February 2024

Modern scientific literature agrees on the issue that it is impossible to perceive public administration as a separate field. Public administration as a field, by general definition, includes the implementation of public policy and the structure and work of various actors (state or non-state) involved in the implementation process. Due to the voluminous nature of the mentioned field, it is not appropriate to consider them separately, because the organizations involved in the process of public policy implementation are not self-generated structures but each organization relies on human resources. Therefore, in the agenda of the scientific space, together with the research in the field of public administration, there was a need to use the results of the research of behavioral science.
The paper specifically deals with the issue of analyzing the necessity of behavioral public administration as a field, which is analyzed through a literature review. The sources used to analyze the mentioned issue include relevant scientific articles and books.
The purpose of the study is to determine and analyze the connection between behavioral science and the field of public administration, and the effectiveness of their combination, which leads to the broader goal of the study, which should answer the question of the necessity and effectiveness of the existence of behavioral public administration as a field.
The relevance of the research stems from the broad nature of the field of public administration, which puts on the agenda the need to combine the achievements of various adjacent fields.
“PENDEKATAN BIMBINGAN KEAGAMAAN DALAM PENGUATAN KEIMANAN TERHADAP MUALLAF (STUDI KASUS PADA KLIEN “R” DI PERUMAHAN DARUSSALAM KABUPATEN MUARA ENIM ).”
Authors: Ardelawati Desi , Cik Sohar Aminullah 
Published: February 2024

This research explores the new and unfamiliar situation of converts. Therefore the convert is in a position of need guidance about the teachings of Islam. In general, religious guidance provides a positive influence on society, especially the convert. Religious guidance on strengthening the faith of believers is considered important because the faith is the driving force of one's life in running the religion and belief. Faith or belief is a spiritual force that becomes the basis of life activities. This study aims to firstly, discuss the problems or problems faced by the convert client "R" post conversion of religion. Secondly, to see how religious activity converts client "R". Third, to examine how the approach of religious guidance in strengthening the faith to the "R" client's conversion. The research method used in this research is qualitative by using data analysis method of case study Robert K Yin. Robert K Yin shares three analytical techniques for case studies: pattern matching, explanation, and time series analysis. The data used can be obtained by the method of observation, interview and documentation. Informants in this study consisted of four people including clients "R", mentors from clients, community leaders and religious leaders. From the results of research obtained from the observation and interview are: First, the problem or problem faced by the convert client "R" post-conversion of religion after the client decided to become a convert he experienced various problems that come after each other, such as family problems, tranquility, adaptation in running the teachings of Islam and disolidaritas social environment. But the client is able to pass all the exams patiently and the client instills in her that she must be strong, God is testing her strength. Secondly, concerning the problem of the client's religious activity in improving his faith, the client carries out the religious activities that exist in the teachings of Islam, not just the obligatory religious activities which he
undertakes but the sunnah as well. Religious activities related to Allah SWT and with the social environment of fellow human beings. Thirdly, the process of religious guidance on the client "R" goes well and gives a positive influence on client's faith. This can be seen from the understanding of the client about the teachings of Islam, the implementation of increased client worship, enthusiasm and enthusiasm of clients in science and attitude and behavior change (akhlakul karimah) in everyday life that the client showed.
COPING SEKSUAL BERBASIS PESANTREN PADA WARGA BINAAN DI RUMAH TAHANAN NEGARA (RUTAN) KLAS II B BATURAJA
Authors: Nugraha Muhammad Arif Indra , Musrin M 
Published: February 2024

For every normal human being and still productive age of sexual necessity is a basic need that is very necessary, so that if this requirement can not be fulfilled it will lead to deviant acts such as homosexual, masturbation, masturbation and other deviations. The problem in this research is how to coping to the assisted citizens in an effort to overcome the pressure because they can not channel their sexual desire in the State Detention Unit (RUTAN) Class II B Baturaja ?, what activities are done in pesantren in assisting sexual coping on the assisted citizens State Detention House (RUTAN) Class II B Baturaja? and how the pesantrenbased sexual coping of the assisted citizens at the State Detention Unit (RUTAN) Class II B Baturaja. The purpose of this research is to know the sexual coping of the assisted citizens who can not channel their sexual desire and the activities of the assisted people in pesantren, and how the pesantren-based sexual coping on the targeted citizens. This research was conducted at State Detention Station (RUTAN) Class II B Baturaja. The type of data used in this study is the type of qualitative data, data sources in this study were taken from primary data and secondary data. Research subjects in this study were the assisted citizens. Data collection techniques include interview method, observation method, documentation method. Data analysis techniques include data reduction, data presentation, data verification or conclusion drawing. From the results of this study obtained that the coping of assisted citizens in an effort to overcome sexual desire is; listening to the voice of the wife from the phone / Wartelpas, chatting with friends in Rutan, lying while imagining his wife, looking at his wife's photos, there also passes time undergoing the period of prisoner sexual desire is by itself not into their mind anymore, and there are citizens built if the desire sexually arises he immediately takes the ablution water and prepares to perform the prayer. Activities undertaken by the assisted people in the pesantren include: studying prayers 5 times, learning to pray the body, adzan, listening to lectures ustadz, studying and fasting. Sexual copies bebasis pesantren conducted by citizens built by the State Detainees (RUTAN) Class II B Baturaja among other methods that are performed by the assisted citizens during the period of detention by following the pesantren activities; pray 5 Time, fast, listen to ustadz lectures, share prayer, and dhikr. The process of pesantren-based
sexual coping on the assisted people is by applying what has been taught in pesantren activities in everyday life such as praying, recitation and dhikr in their room, if the desire arises they immediately take ablution water and prepare to pray.
Pengembangan Modul Bimbingan Karir Teori Anne Roe Terhadap Perencanaan Karir Siswa
Authors: Turrohmah Habiba , Karamoy Yurike Kinanthy , Prawita Sri 
Published: February 2024

A module is a set of subject matter that is arranged systematically and sequentially to make it easier for students to achieve appropriate competencies accompanied by guidelines for use. The existence of modules can be utilized by BK teachers to carry out services in schools such as career guidance for student career planning. This research aims to create a module design regarding Anne Roe's career planning theory in order to produce a module that is suitable for use by class VIII students at SMPN 03 Tanggul. This research uses R&D (Research and Development) development research using the Borg and Gall development model which includes 6 of 10 stages, namely: Research and information collecting, Planning, Develop preliminaryform of product, Preliminary field testing, Main product revision, Research subjects include: Expert Test 1 tests the suitability of the material for the product, Expert Test 2 tests the suitability of the product for BK services. The data collection method uses a questionnaire. There is a questionnaire used or called a validation sheet which is used by expert tests. The results of this research assessment include: expert test 1 obtained a percentage score of 73% with good criteria and stated that the module, while expert test 2 obtained a percentage score of 91% with very good criteria. The results of small group test calculations consisting of 6 class VIII students at SMPN 03 Tanggul showed that the practicality percentage value of the module developed was 72%, which was declared "Practical" and met the practicality criteria
Keywords: Module, Anne Roe theory, Career planning
PEMBANGUNAN TRANSPORTASI KERETA API JALUR GOENDIH (GROBOGAN) – SOERABAJA TAHUN 1903-1922
Authors: Panjaitan Erik Pratama Manaor , Winarni Retno 
Published: February 2024

This study examines the Goendih-Soerabaja railway line for the period 1903-1922. The purpose of this study is to explain the reasons for the construction of the railroad, the process of building the railroad, and its impact on the surrounding community. The results of this study indicate that the construction of the Goendih-Soerabaja railway line had a positive impact on the economy of the Dutch East Indies Government. Inaugurated on February 1, 1903, rail transportation encouraged economic growth in areas that became the path of the Goendih-Soerabaja railroad. The forced cultivation system has had a major impact on plantations, problems that have occurred due to the damage of export commodities before arriving at the port can now be resolved by the presence of rail transportation. Another factor is that the start of oil drilling operations in the Tjepu area has created the need for large-capacity oil transport in shipping to ports. Another impact of the existence of rail transportation is that the mobility of people who travel now saves more travel time.
Keywords: Infrastructure; Railroad Extension; Goendih – Soerabaja Line; Capitalist Economy.
Quantifying Interfacial Reactions in Lithium Metal Batteries for a New Paradigm of Long-Cycling Electrolyte Designs
Authors: Wang Hansen , Zhang Rupeng , Yan Xiaolin , Sun Juanjuan , Feng Fuxiang , Li Haoran , Wang Yuchun , Ye Guangzhou , Huang Shengyuan , Wan Pan , Luo Xiaonan , Chen Fangyun , Ulissi Ulderico , Ge Xiaoming , Liu Chengyong , Xu Bo , Ouyang Chuying 
Published: February 2024

Abstract

Side reactions at electrolyte-electrode interfaces are the key to failures of lithium metal batteries (LMBs). Recent works fell short of rationalizing the whole picture of interfacial reactions quantitatively. Here we develop and combine multiple techniques to systematically study the interfacial reactions in LMBs with an ether-based electrolyte. Reduction, oxidation pathways of lithium salt and organic solvents, formation of key solid-electrolyte interphase (SEI) species such as LiH and Li2CO3, gas generation and its cross-talk, are quantitatively mapped out. We find that the reduction of lithium bis(fluorosulfonyl)imide (LiFSI) salt is the dominant cause of both electrolyte “dry-out” and lithium inventory loss. FSI anion-derived SEI has significantly promoted lithium metal cycleablity, but it now becomes the limiting factor for the long cycling of LMBs. Based on these findings, we propose a new paradigm for long-cycling electrolyte design, where LiFSI content is maximized without compromising viscosity and ionic conductivity. Following this strategy, we prolong the life of a LMB to nearly 500 cycles under 20 μm Li and 2.1 g/Ah lean electrolyte conditions. Our work demonstrates a bottom-up design methodology where electrolyte formulations are iterated based on a clear understanding of cell failure mechanisms.
A noncanonical E3 ubiquitin ligase RNF41-mediated MYO1C stability promotes prostate cancer metastasis by inducing actin remodeling
Authors: xu Songhui , Xiong Situ , Li Sheng , Li Zhongqi , Song Yanping , Dong Qianxi , Yang Lin , Xiong Yunqiang , Zhan Xiangpeng , Yang Hailang , Hu Hongji , Zheng Fuchun , Wan Hao , Liu Jiahao , Wang Zhipeng , Wu Shuyu , Du Yuanzhuo , Biao Guo , Jing Xiong , Pan Wang , Guo Ju , Fu Bin 
Published: February 2024

Abstract
Prostate cancer bone metastasis is a predominant cause of death for prostate cancer (PCa) patients. However, the underlying mechanisms are poorly understood. Here, we report that high levels of RNF41 are associated with metastatic human prostate cancer. RNF41 silencing inhibits prostate cancer cell growth, cell migration and invasion in vitro and in vivo. Mechanistically, we identify that RNF41 induces K27- and K63-linked noncanonical polyubiquitination of MYO1C to enhance its stability and induce actin remodeling, which promotes PCa bone metastasis. RNF41 was significantly up-regulated in metastatic prostate cancer tissues and positively associated with MYO1C expression. Furthermore, we show in intraarterial injected- bone metastasis xenograft model that targeting MYO1C stability by inhibition of RNF41 markedly suppressed PCa bone metastasis. Collectively, our findings identify RNF41 is an important regulator of prostate cancer cell growth and metastasis and targeting RNF41/MYO1C could be a valuable strategy to ameliorate prostate cancer progression and metastasis.