bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Power of Energy Justice for Attaining and Maintaining Acceptance for Renewable Energy Projects
Authors: Vega-Araújo José 
Published: December 2023

AbstractThe renewable energy (RE) industry faces a significant challenge globally: gaining and maintaining social acceptance. Social acceptance of RE projects, including associated infrastructure such as transmission lines, is deeply rooted in justice and equity concerns regarding environmental and social impacts, cultural implications, land use conflicts, and the legitimacy of consultation processes, among others. This paper argues that if addressing injustices is a condition for securing social acceptance, energy justice can serve as both a goal and roadmap to unfold acceptability towards RE projects while serving to identify critical elements that must be addressed. It does so by outlining considerations for achieving energy justice in RE projects and presenting an example on the role, potentialities, and challenges of the figure of community advisors as critical actors for ensuring energy justice.
Solving Energy Justice in the European Union
Authors: Czarnecka Marzena , Krazniewski Marcin 
Published: December 2023

AbstractThe electricity sector will play a key role in the energy transition. In particular, this can have a transformative affect in the European Union (EU). One of the key aspects of EU policy that can contribute to energy transition is the role of energy communities. Prioritising low-income communities and communities of colour is necessary as these are disproportionately impacted by energy poverty. Community ownership can provide communities with a voice in energy production and distribution. Promoting energy communities can enable the development of clean energy development which overall can contribute to a just transition to a low-carbon economy.
The Formation of Energy Law as a Discipline That Integrates the Principle of Energy Justice
Authors: López-Ibor Mayor Vicente , López-Ibor Mayor E. J. I. 
Published: December 2023

AbstractJustice and energy are undoubtedly a combination of the highest importance. It touches the most important values and foundations of society. It also brings together important elements such as energy and climate policy, regulation and principles of energy law. The transition requires overarching principles that are valid and applicable to all energy sources, hence the importance of identifying energy justice as a principle, its constituent elements and its legal, technical and economic implications. Energy justice, in turn, requires that energy law considers the entire supply chain; the impacts and projections, from the extraction or use of raw materials to infrastructure development, transformation and provision of economic general services of general interest.
Energy Justice as a Key to Achieve Affordable Energy
Authors: Fourcade Gonzalo Irrazabal Pérez 
Published: December 2023

AbstractThis chapter addresses the relationship between affordable energy and energy justice. Inevitably, affordability is obtained when there is fair distribution of the energy benefits and burdens, meaning securing affordable energy to all. Additionally, this chapter explores different restrictions, limitations and barriers that nations may face when achieving affordable energy with energy justice. In order to overpass those challenges, governments, financial institutions and consumers should re-think the instruments to achieve the ultimate goal. Some new tools are proposed for all the mentioned players, including boosting energy education as a key driver to engage consumers into the energy system.
Automating Value-Oriented Forecast Model Selection by Meta-learning: Application on a Dispatchable Feeder
Authors: Werling Dorina , Beichter Maximilian , Heidrich Benedikt , Phipps Kaleb , Mikut Ralf , Hagenmeyer Veit 
Published: December 2023

AbstractTo successfully increase the share of renewable energy sources in the power system and for counteract their fluctuating nature in view of system stability, forecasts are required that suit downstream applications, such as demand side management or management of energy storage systems. However, whilst many forecast models to create these forecasts exist, the selection of the forecast model best suited to the respective downstream application can be challenging. The selection is commonly based on quality measures (such as mean absolute error), but these quality measures do not consider the value of the forecast in the downstream application. Thus, we introduce a meta-learning framework for forecast model selection, which automatically selects the forecast model leading to the forecast with the highest value in the downstream application. More precisely, we use a meta-learning approach that considers the selection task as a classification problem. Furthermore, we empirically evaluate the proposed framework on the downstream application of a smart building’s photovoltaic-battery management problem known as dispatchable feeder on building-level with a data set containing time series from 300 buildings. The results of our evaluation demonstrate that the proposed framework reduces the cost and improves the accuracy compared to existing forecast model selection heuristics. Furthermore, compared to a manual forecast model selection, it requires noticeably less computational effort and leads to comparable results.
Akzeptanz und Nutzbarkeit automatisiertes Fahren
Authors: Abendroth Bettina , Joisten Philip , Schaarschmidt Erik , Gianneli Tania 
Published: December 2023

ZusammenfassungDie Einführung eines automatisierten ÖPNV schafft für alle ein neues Mobilitätsangebot. Das Kap. 4 beschreibt, wie durch die Analyse von Motiven der Verkehrsmittelwahl Rahmenbedingungen abgeleitet werden können, die die Nutzung des automatisierten ÖPNV fördern. Um Menschen von der Nutzung des automatisierten ÖPNV zu überzeugen, ist es wichtig, den Mensch als Fahrgast in den Mittelpunkt der Gestaltung von Mobilitätsangeboten zu stellen und seine spezifischen Bedürfnisse zu erfüllen. Mobilitätsangebote umfassen die gesamte Customer Journey, d. h. neben der eigentlichen Fahrt muss der gesamte Prozess aus Sicht eines Fahrgastes von der Planung einer Fahrt bis zum Erreichen des Zielortes betrachtet werden. Ein wesentlicher Aspekt für die Akzeptanz der Bevölkerung eines automatisierten ÖPNV ist die Verkehrssicherheit der anderen Verkehrsteilnehmenden. Daher schließt das Kap. 4 mit der Kommunikation zwischen avF und anderen Verkehrsteilnehmenden und macht dazu konkrete Handlungsempfehlungen.
Handlungsleitfaden zur Integration automatisierten Fahrens
Authors: Pitzen Constantin , Monheim Heiner , Zweig Mario , Yen Robert , Marquardt Christoph 
Published: December 2023

ZusammenfassungDas Kap. 7 soll dem Leser möglichst praktische Ideen und Vorgehensweisen für die Integration eines automatisierten ÖPNV zur Verfügung stellen. Dabei bildet die Reihenfolge der Kapitel bereits einen Handlungsleitfaden: Beginnend mit der Frage ‚Wie ist bei der Integration automatisierten Fahrens vorzugehen?‘, ‚Was ist verkehrs- und raumplanerisch bei der Implementierung eines automatisierten ÖPNV zu beachten?‘ über die Frage ‚Wie kann ein automatisiertes Fahrzeug oder eine automatisiert fahrende Transportdienstleistung beschafft und implementiert werden?‘ und die Zulassung der automatisierten Fahrzeuge endet das Kapitel mit einem Einblick in die betriebliche Umsetzung eines automatisierten ÖPNV aus der Sicht eines Verkehrsunternehmens. Zur Illustration wird ein hypothetisches Projekt am Beispiel der bayrischen Kleinstadt Lindau am Bodensee beigesteuert, das die Implementierung zweier automatisierter ÖPNV-Linien als ein Instrument innerhalb vieler Maßnahmen für das Gelingen der Mobilitätswende beschreibt.
Sparse random matrices and Gaussian ensembles with varying randomness
Authors: Anegawa Takanori , Iizuka Norihiro , Mukherjee Arkaprava , Sake Sunil Kumar , Trivedi Sandip P. 
Published: December 2023

Abstract
We study a system of N qubits with a random Hamiltonian obtained by drawing coupling constants from Gaussian distributions in various ways. This results in a rich class of systems which include the GUE and the fixed q SYK theories. Our motivation is to understand the system at large N. In practice most of our calculations are carried out using exact diagonalisation techniques (up to N = 24). Starting with the GUE, we study the resulting behaviour as the randomness is decreased. While in general the system goes from being chaotic to being more ordered as the randomness is decreased, the changes in various properties, including the density of states, the spectral form factor, the level statistics and out-of-time-ordered correlators, reveal interesting patterns. Subject to the limitations of our analysis which is mainly numerical, we find some evidence that the behaviour changes in an abrupt manner when the number of non-zero independent terms in the Hamiltonian is exponentially large in N. We also study the opposite limit of much reduced randomness obtained in a local version of the SYK model where the number of couplings scales linearly in N, and characterise its behaviour. Our investigation suggests that a more complete theoretical analysis of this class of systems will prove quite worthwhile.
Abelson Helper Integration Site 1 haplotypes and peripheral blood expression associates with lithium response and immunomodulation in bipolar patients
Authors: Sakrajda Kosma , Bilska Karolina , Czerski Piotr M. , Narożna Beata , Dmitrzak-Węglarz Monika , Heilmann-Heimbach Stefanie , Brockschmidt Felix F. , Herms Stefan , Nöthen Markus M. , Cichon Sven , Więckowska Barbara , Rybakowski Janusz K. , Pawlak Joanna , Szczepankiewicz Aleksandra 
Published: December 2023

Abstract
Rationale
In bipolar disorder (BD), immunological factors play a role in the pathogenesis and treatment of the illness. Studies showed the potential link between Abelson Helper Integration Site 1 (AHI1) protein, behavioural changes and innate immunity regulation. An immunomodulatory effect was suggested for lithium, a mood stabilizer used in BD treatment.

Objectives
We hypothesized that AHI1 may be an important mediator of lithium treatment response. Our study aimed to investigate whether the AHI1 haplotypes and expression associates with lithium treatment response in BD patients. We also examined whether AHI1 expression and lithium treatment correlate with innate inflammatory response genes.

Results
We genotyped seven AHI1 single nucleotide polymorphisms in 97 euthymic BD patients and found that TG haplotype (rs7739635, rs9494332) was significantly associated with lithium response. We also showed significantly increased AHI1 expression in the blood of lithium responders compared to non-responders and BD patients compared to healthy controls (HC). We analyzed the expression of genes involved in the innate immune response and inflammatory response regulation (TLR4, CASP4, CASP5, NLRP3, IL1A, IL1B, IL6, IL10, IL18) in 21 lithium-treated BD patients, 20 BD patients treated with other mood stabilizer and 19 HC. We found significantly altered expression between BD patients and HC, but not between BD patients treated with different mood stabilizers.

Conclusions
Our study suggests the involvement of AHI1 in the lithium mode of action. Moreover, mood-stabilizing treatment associated with the innate immunity-related gene expression in BD patients and only the lithium-treated BD patients showed significantly elevated expression of anti-inflammatory IL10, suggesting lithium’s immunomodulatory potential.
Marine heatwaves as drivers of biological and ecological change: implications of current research patterns and future opportunities
Authors: Joyce Patrick W. S. , Tong Cindy B. , Yip Yuk Long , Falkenberg Laura J. 
Published: December 2023

AbstractAs humans accelerate global environmental change, extreme climatic events are increasing in frequency, duration, and intensity. In marine environments, extreme events of particular concern are marine heatwaves (MHWs). Previous reviews synthesising subsets of field-based research examining the ecological effects of these short-term warming events have found they could drive important changes to ecosystems. Here, we reviewed the traits of published literature that has used field, laboratory, and modelling approaches to examine the biotic effects of MHWs, and highlight some of the key findings. Since its first use in this context in 2013, the term “marine heatwave” has generally been used in field-based literature primarily documenting changes in abundance, biodiversity, species distributions, and mortality, primarily in fish and molluscs. Research is increasingly also conducted in laboratory settings, with these investigations focussing on changes in mechanistic processes such as growth and biochemical responses, often in smaller or less motile organisms including seagrasses, algae, molluscs, and crustaceans. Given their different applications, these complementary approaches will provide a more complete understanding when used to consider the same taxonomic groups. Moreover, those manipulating MHWs in laboratory experiments could benefit from the consideration of a range of MHW traits (intensity, duration, and their combination), for species in both isolation and combination, and in the presence of additional abiotic stressors. As such, where future research into MHWs use varied approaches and treatment settings, they will contribute to a more holistic understanding of the biological and ecological effects of future short-term warming events in our ocean.
Perspectives in Searching Antimicrobial Peptides (AMPs) Produced by the Microbiota
Authors: Gallardo-Becerra Luigui , Cervantes-Echeverría Melany , Cornejo-Granados Fernanda , Vazquez-Morado Luis E. , Ochoa-Leyva Adrian 
Published: December 2023

AbstractChanges in the structure and function of the microbiota are associated with various human diseases. These microbial changes can be mediated by antimicrobial peptides (AMPs), small peptides produced by the host and their microbiota, which play a crucial role in host-bacteria co-evolution. Thus, by studying AMPs produced by the microbiota (microbial AMPs), we can better understand the interactions between host and bacteria in microbiome homeostasis. Additionally, microbial AMPs are a new source of compounds against pathogenic and multi-resistant bacteria. Further, the growing accessibility to metagenomic and metatranscriptomic datasets presents an opportunity to discover new microbial AMPs. This review examines the structural properties of microbiota-derived AMPs, their molecular action mechanisms, genomic organization, and strategies for their identification in any microbiome data as well as experimental testing. Overall, we provided a comprehensive overview of this important topic from the microbial perspective.
Early response monitoring during [177Lu]Lu-PSMA I&T therapy with quantitated SPECT/CT predicts overall survival of mCRPC patients: subgroup analysis of a Swiss-wide prospective registry study
Authors: Neubauer Moritz C. , Nicolas Guillaume P. , Bauman Andreas , Fani Melpomeni , Nitzsche Egbert , Afshar-Oromieh Ali , Forrer Flavio , Rentsch Cyril , Stenner Frank , Templeton Arnoud , Schäfer Niklaus , Wild Damian , Chirindel Alin ,   all investigators on behalf of the SSNM Therapy Working Group
Published: December 2023

Abstract
Purpose
To assess early tumor response with quantitated SPECT/CT and to correlate it with clinical outcome in metastatic castration–resistant prostate cancer (mCRPC) patients treated with 177Lutetium-PSMA I&T therapy.

Methods
Single-center, observational study, part of the prospective Swiss national cancer registry study investigating the safety and efficacy of [177Lu]Lu-PSMA I&T (EKNZ: 2021–01271) in mCRPC patients treated with at least two cycles of [177Lu]Lu-PSMA I&T 6-weekly. After the first and second cycle quantitated SPECT/CT (Symbia Intevo, Siemens) was acquired 48 h after injection (three fields of view from head to thigh, 5 s/frame) and reconstructed using xQuant® (48i, 1 s, 10-mm Gauss). Image analysis: The PSMA-positive total tumor volumes (TTV) were semi-automatically delineated using a SUV threshold of 3 with MIMencore® (version 7.1.3, Medical Image Merge Software Inc.). Changes in TTV, highest tumor SUVmax, and total tumor SUVmean between cycles 1 and 2 were calculated and grouped into a) stable or decrease and b) increase. Serum PSA levels were assessed at each therapy cycle and at follow-up until progression or death. Changes in TTV, PSA, SUVmax, and SUVmean were correlated with PSA-progression-free survival (PSA-PFS) and the overall survival (OS) using the Kaplan–Meier methodology (log-rank test).

Results
Between 07/2020 and 04/2022, 111 patients were screened and 73 finally included in the data analysis. The median follow-up was 8.9 months (range 1.4–26.6 months). Stable or decreased TTV at cycle 2 was associated with longer OS (hazard ratio (HR) 0.28, 95% confidence interval (CI) 0.09–0.86, p < 0.01). Similar, stable, or decreased PSA was associated with longer OS (HR 0.21; CI 0.07–0.62, p < 0.01) and PSA-PFS (HR 0.34; 95% CI 0.16–0.72, p < 0.01). Combining TTV and PSA will result in an augmented prognostic value for OS (HR 0.09; CI 0.01–0.63; p < 0.01) and for PSA-PFS (HR 0.11; CI 0.02–0.68; p < 0.01). A reduction of SUVmax or SUVmean was not prognostically relevant, neither for OS (p 0.88 and 0.7) nor for PSA-PFS (p 0.73 and 0.62, respectively).

Conclusion
Six weeks after initiating [177Lu]Lu-PSMA I&T, TTV and serum PSA appear to be good prognosticators for OS. Combined together, TTV + PSA change demonstrates augmented prognostic value and can better predict PSA-PFS. Larger studies using TTV change prospectively as an early-response biomarker are warranted for implementing management change towards a more personalized clinical practice.
Superinfection and the hypnozoite reservoir for Plasmodium vivax: a general framework
Authors: Mehra Somya , McCaw James M. , Taylor Peter G. 
Published: December 2023

AbstractA characteristic of malaria in all its forms is the potential for superinfection (that is, multiple concurrent blood-stage infections). An additional characteristic of Plasmodium vivax malaria is a reservoir of latent parasites (hypnozoites) within the host liver, which activate to cause (blood-stage) relapses. Here, we present a model of hypnozoite accrual and superinfection for P. vivax. To couple host and vector dynamics for a homogeneously-mixing population, we construct a density-dependent Markov population process with countably many types, for which disease extinction is shown to occur almost surely. We also establish a functional law of large numbers, taking the form of an infinite-dimensional system of ordinary differential equations that can also be recovered by coupling expected host and vector dynamics (i.e. a hybrid approximation) or through a standard compartment modelling approach. Recognising that the subset of these equations that model the infection status of the human hosts has precisely the same form as the Kolmogorov forward equations for a Markovian network of infinite server queues with an inhomogeneous batch arrival process, we use physical insight into the evolution of the latter process to write down a time-dependent multivariate generating function for the solution. We use this characterisation to collapse the infinite-compartment model into a single integrodifferential equation (IDE) governing the intensity of mosquito-to-human transmission. Through a steady state analysis, we recover a threshold phenomenon for this IDE in terms of a parameter $$R_0$$

R
0

expressible in terms of the primitives of the model, with the disease-free equilibrium shown to be uniformly asymptotically stable if $$R_0<1$$

R
0

<
1

and an endemic equilibrium solution emerging if $$R_0>1$$

R
0

>
1

. Our work provides a theoretical basis to explore the epidemiology of P. vivax, and introduces a strategy for constructing tractable population-level models of malarial superinfection that can be generalised to allow for greater biological realism in a number of directions.
Collagenase-producing bacteria are common in anastomotic leakage after colorectal surgery: a systematic review
Authors: Jørgensen Anders Bech , Jonsson Isabella , Friis-Hansen Lennart , Brandstrup Birgitte 
Published: December 2023

Abstract
Purpose
Some gut bacteria can produce enzymes (collagenases) that can break down collagen in the intestinal wall. This could be a part of the pathophysiology of anastomotic leakage (AL). This systematic review aimed to investigate if such bacteria were present more frequently in AL patients versus non-AL patients following colorectal surgery.

Methods
This systematic review was reported according to the PRISMA and AMSTAR guidelines. Before the literature search, a study protocol was registered at PROSPERO (CRD42022363454). We searched PubMed, EMBASE, Google Scholar, and Cochrane CENTRAL on April 9th, 2023, for randomized and observational human studies of AL following colorectal surgery with information on gastrointestinal bacteria. The primary outcome was bacteria with the potential to produce collagenase. The risk of bias was assessed with the Newcastle–Ottawa Scale, as all studies were observational.

Results
We included 15 studies, with a total of 52,945 patients, of which 1,747 had AL, and bacteriological information from feces, mucosa, the resected specimen, or drain fluid was presented. In 10 of the 15 studies, one or more collagenase-producing bacteria were identified in the patients with AL. Neither the bacteria nor the collagenase production were quantified in any of the studies. The studies varied greatly in terms of sample material, analytical method, and time of collection. Studies using DNA sequencing methods did not report findings of collagenase-producing bacteria.

Conclusion
Collagenase-producing bacteria are more common in patients with AL following colorectal surgery than in patients without AL, but the significance is unclear. From the current studies, it is not possible to determine the pathogenicity of the individual gut bacteria.
Resilient Livelihood Styles: An enriched perspective on household livelihood resilience in the sensitive natural environments of Indonesia
Authors: Kuipers Kimberly , de Jong Edwin B. P. 
Published: December 2023

AbstractLivelihood resilience has rapidly gained relevance in discussions and policies concerning groups and communities challenged by diverse natural and man-made adversities. Most studies seeking to understand how people respond, recover and adapt to shocks and stresses focus on changes in material or financial resources on the community or larger scales. They thereby often disregard differences in household-level practices and the influence of social-cultural structures in building livelihood resilience. We adopt the concept of livelihood styles to explore a more differentiated and ‘subjective’ conceptualisation of resilient livelihoods. By applying a mixed-methods approach, we scrutinised the ways in which various livelihood styles have evolved to adapt to their changing environment in the Maninjau caldera, Indonesia. We found that different livelihood styles show differing levels of adaptability in terms of resilience. This is largely due to the historic evolvement of styles and the way in which they are embedded in social structures. Styles that show higher levels of resilience to changes in the natural environment also appear to be more contumacious towards development interventions that are geared towards new forms of living with the objective of raising people’s income. As such, we show that a resilient livelihood styles perspective offers a way of identifying and interrogating the characteristics that build resilience of household livelihoods that better reflect the reality of local households. It can contribute to the development of more inclusive interventions and policymaking in ecologically sensitive areas that take account of and anticipate transformational environmental changes and the creation of sustainable livelihoods.