bluuebunny/crossref_metadata_2025_split huggingface dataset:
Changes in thyroid function levels in female patients with first-episode bipolar disorder
Authors: Song Xiuhua , Feng Yufang , Yi Lei , Zhong Baoliang , Li Yi 
Published: November 2023

ObjectivesThe identification of molecular biomarkers for bipolar disorder is anticipated to greatly improve the diagnosis and treatment of this disease. The objective of this case–control study is to determine whether the blood thyroid hormone levels in bipolar disorder patients are associated with different types of first onset.MethodsFrom August 1, 2020 to July 31, 2021 a total of 120 female patients diagnosed with bipolar disorder and hospitalized at Qingdao Mental Health Center were recruited as the case group, including 60 patients with depression as their first onset (depression first-episode group, DF) and 60 with mania/hypomania as their first onset (mania/hypomania first-episode group, M/HF). A group of 60 healthy adult females matching general demographic data, such as race and age, were selected as the control group. Blood samples were taken from both groups to measure serum triiodothyronine (T3), thyroxine (T4), free triiodothyronine (FT3), free thyroxine (FT4), and thyroid stimulating hormone (TSH) concentrations.ResultsThe duration of current onset in the M/HF group was significantly less than that in the DF group (23.1 ± 20.2 vs. 125.2 ± 41.0 days). About 27% of patients in the M/HF group had thyroid abnormalities, in contrast to 60% in the DF group. The blood T3 and T4 levels in both the M/HF group and the DF group, as well as the TF3 levels in the DF group, were significantly lower as compared to control. The M/HF group had significantly higher T3 and FT3 levels than the DF group. The blood T3 levels were inversely correlated with the Young’s Mania Scale score and the Hamilton Depression Scale score in both the M/HF and DF groups.ConclusionThyroid dysfunction resulting in reduced levels of blood thyroid levels may be involved in the disease progression of bipolar disorder, and correlated with the clinical symptoms in patients with depression or mania as the first episode.
Do the American guideline-based leisure time physical activity levels for civilians benefit the mental health of military personnel?
Authors: Tsai Kun-Zhe , Liu Pang-Yen , Lin Yen-Po , Chu Chen-Chih , Huang Wei-Chun , Sui Xuemei , Lavie Carl J. , Lin Gen-Min 
Published: November 2023

BackgroundsThis study aimed to clarify the association of American guideline-based leisure time physical activity (PA) level with mental health in 4,080 military personnel in Taiwan.MethodsThe moderate intensity PA level was assessed according to the total running time per week (wk) reported in a self-administered questionnaire over the previous 6  months and was categorized into PA level &lt;150, 150–299, and ≥300  min/wk. Mental stress was assessed by the Brief Symptom Rating Scale (BSRS)-5 for which ≥15 points were classified as great mental stress. Suicide ideation (SI) was graded as 1 for mild, 2 for moderate, and 3 or 4 for severe. Multivariable logistic regression analysis was employed to determine the association between PA and mental health while adjusting for demographics, smoking, alcohol intake, betel nut chewing, and obesity.ResultsAs compared to participants with a PA level of &lt;150  min/wk., those with PA levels 150–299  min/wk. and ≥  300  min/wk. had a lower possibility of SI ≥1 [odds ratios (ORs) and 95% confidence intervals (CIs): 0.58 (0.40–0.83) and 0.23 (0.14–0.36), respectively] and SI ≥1 and/or BSRS-5 ≥  15 [ORs: 0.55 (0.39–0.79) and 0.21 (0.13–0.34), respectively]. The possibilities were more significantly lower for SI ≥2 [ORs: 0.37 (0.20–0.68) and 0.10 (0.04–0.26), respectively] and SI ≥2 and/or BSRS-5 ≥  15 [ORs: 0.35 (0.20–0.62) and 0.10 (0.04–0.25), respectively].ConclusionOur findings indicate that participating in moderate-intensity leisure time PA level for ≥150  min/wk. may have a positive effect on mental health among military personnel. The impact appears to be even more significant when engaging in a higher PA level of ≥300  min/wk.
External quality assessment for laboratories in pan-India ILI/SARI surveillance for simultaneous detection of influenza virus and SARS-CoV-2
Authors: Potdar Varsha , Vijay Neetu , Vipat Veena , Jadhav Sheetal , Gupta Nivedita , Aggarwal Neeraj 
Published: November 2023

IntroductionThe Indian Council of Medical Research has set up a nationwide network of 28 laboratories for simultaneous surveillance of influenza virus and SARS-CoV-2 in ILI/SARI patients, using an in-house developed and validated multiplex real-time RTPCR assay. The aim of this study was to ensure the quality of testing by these laboratories by implementing an external quality assessment program (EQAP).MethodsFor this EQAP, a proficiency test (PT) panel comprising tissue-culture or egg-grown influenza virus and SARS-CoV-2 was developed. The PT panel was distributed to all the participant laboratories, which tested the panel and submitted the qualitative results online to the EQAP provider. The performance of the laboratories was evaluated on qualitative criteria but cycle threshold (Ct) values were also gathered for each sample.ResultsOn a qualitative basis, all the laboratories achieved the criteria of 90% concordance with the results of the PT panel provider. Ct values of different samples across the laboratories were within ≤ ±3 cycles of the corresponding mean values of the respective sample. The results of this EQAP affirmed the quality and reliability of testing being done for simultaneous surveillance of influenza virus and SARS-CoV-2 in India.
Comprehensive assessment of emergency departments in county-level public hospitals: a multicenter descriptive cross-sectional study in Henan province, China
Authors: Cheng Yanwei , Cao Xue , Zhang Jiange , Xu Lijun , Qin Lijie 
Published: November 2023

BackgroundEmergency Departments (EDs) play a crucial role in providing immediate medical care, particularly in densely populated countries like China. While previous research has predominantly focused on well-funded urban hospitals, this study offers a comprehensive evaluation of EDs in county-level public hospitals in Henan province, China, aiming to identify disparities and challenges.MethodsA descriptive cross-sectional survey was conducted in 382 public hospitals across Henan province, China, from July 1, 2023, to August 1, 2023. Data were collected using an electronic questionnaire covering hospital information, human resources, infrastructure, clinical capabilities, and operational capacities. The data collection period for this survey spanned from January 1 to December 31, 2022.ResultsWith a remarkable 94.0% response rate, our study reveals significant disparities in county-level public hospitals compared to their provincial or municipal counterparts in Henan Province, China. County-level hospitals, which constitute 266 of the total 342 surveyed facilities, exhibit notable differences, including fewer doctors (median: 11 vs. 23, p &lt; 0.0001) and nurses (median: 18 vs. 37, p &lt; 0.0001). Additionally, a higher proportion of junior doctors is observed in these hospitals, while senior medical staff are more prevalent in provincial or municipal hospitals (p &lt; 0.001). County-level hospitals also face resource challenges, with fewer beds in the emergency room (median: 4 vs. 7, p = 0.0003) and limited proficiency in advanced clinical procedures such as POCT, fiberoptic bronchoscopy, CRRT, ECMO, ultrasound equipment operation, and intraosseous infusion, with significant differences noted in most of these capabilities (p &lt; 0.05). Operational capabilities show distinctions as well, with county-level hospitals managing a lower patient volume (median: 14,516 vs. 34,703, p &lt; 0.0001) and handling fewer pre-hospital CPR cases (median: 33 vs. 89, p &lt; 0.0001). In-hospital CPR success rates are also lower in county-level hospitals (median ROSC: 25.0% vs. 42.8%, p = 0.0068).ConclusionWhile provincial or municipal hospitals enjoy better resources, county-level hospitals, especially crucial in less urbanized regions, face substantial challenges. Addressing these disparities is imperative, necessitating targeted investments, improved infrastructure, enhanced clinical training, and the adoption of innovations like telemedicine to enhance the quality of emergency care.
Bacteriome analysis of Aggregatibacter actinomycetemcomitans-JP2 genotype-associated Grade C periodontitis in Moroccan adolescents
Authors: Molli Vijaya Lakshmi Pavani , Kissa Jamila , Baraniya Divyashri , Gharibi Amina , Chen Tsute , Al-Hebshi Nezar N. , Albandar Jasim M. 
Published: November 2023

BackgroundGrade C (previously aggressive) periodontitis (GCP) in adolescents is prevalent in certain parts of Africa where it is associated with JP2 genotype, a highly virulent strain of Aggregatibacter actinomycetemcomitans. The aim of this study was to characterize the subgingival bacteriome in Moroccan subjects with GCP positive to A. actinomycetemcomitans JP2 genotype.MethodsSubgingival plaque samples were collected from shallow and deep pockets of 8 subjects with GCP (17.2 ± 1.5 years) and from gingival sulci of 13 controls with no periodontitis (14.6 ± 1.1 years). Identification and genotyping of A. actinomycetemcomitans was performed using PCR analysis of the ltx operon, while bacteriome profiling was done by 16S rRNA gene sequencing (V1–V3 region). Groups were compared in terms of microbial diversity, abundances, and dysbiosis.ResultsThe shallow and deep pocket sites from GCP cases had a significantly altered microbial composition compared to controls. Species associated with health included Haemophilus parainfluenzae, Lautropia mirabilis, Streptococcus spp., Gemella spp., and Rothia spp. While known periodontal pathogens, including Porphyromonas gingivalis, Tannerella forsythia, Treponema spp. and Fretibacterium spp., were significantly enriched in GCP, non-conventional taxa, including Pseudomonas oral taxon C61 and Enterobacter cloacae were more abundant and showed stronger association with the disease. Less significant differences in abundances of individual taxa were observed between shallow and deep pockets. Overall dysbiosis measured in terms of Subgingival Microbial Dysbiosis Index (SMDI) differentiated between GCP and no-periodontitis with 95% accuracy.ConclusionsThe results suggest that several periodontal pathogens involved in the adult-type periodontitis also play a role in JP2 genotype-associated GCP. The potential role of non-conventional taxa in the pathogenesis of GCP warrants further investigation.
Basketball talent identification: a systematic review and meta-analysis of the anthropometric, physiological and physical performance factors
Authors: Han Miaoyu , Gómez-Ruano Miguel-Angel , Calvo Alberto Lorenzo , Calvo Jorge Lorenzo 
Published: November 2023

BackgroundThe purpose of this study was to do a systematic review and meta-analysis about the anthropometric, physiological, and physical performance that discriminate the physical talent in basketball.MethodsThe search was conducted using the most relevant databases as Web of Science, PubMed, SPORTDiscus and Scopus, according to the PRISMA (2020) guideline. Keywords such as “basketball”, “talented identification”, “anthropometric”, “physiology” and “physical performance” were used for the search, in English and following the “PICOS” question model. Eighteen articles' overall methodological quality was assessed using the Critical Review Forms.ResultsThe study found in basketball, height, body mass, Yo-Yo test, T-test, 20 m sprint, and jump performance had statistical significance between elite and non-elite groups, including different positions and levels.ConclusionsThe reviewed literature highlighted a complicated relationship between anthropometric, physiological, and physical performance. Based on the results of the study, it's possible that height, body mass, agility, speed, endurance capacity, and lower lamb power could affect the early development of basketball.
Physiological and skeletal muscle responses to high-intensity interval exercise in Thoroughbred horses
Authors: Mukai Kazutaka , Ohmura Hajime , Takahashi Yuji , Ebisuda Yusaku , Yoneda Koki , Miyata Hirofumi 
Published: November 2023

IntroductionThe purpose of this study was to determine whether acute high-intensity interval exercise or sprint interval exercise induces greater physiological and skeletal muscle responses compared to moderate-intensity continuous exercise in horses.MethodsIn a randomized crossover design, eight trained Thoroughbred horses performed three treadmill exercise protocols consisting of moderate-intensity continuous exercise (6 min at 70% VO2max; MICT), high-intensity interval exercise (6 × 30 s at 100% VO2max; HIIT), and sprint interval exercise (6 × 15 s at 120% VO2max; SIT). Arterial blood samples were collected to measure blood gas variables and plasma lactate concentration. Biopsy samples were obtained from the gluteus medius muscle before, immediately after, 4 h, and 24 h after exercise for biochemical analysis, western blotting and real-time RT-PCR. Effects of time and exercise protocol were analyzed using mixed models (p &lt; 0.05).ResultsHeart rate and plasma lactate concentration at the end of exercise were higher in HIIT and SIT than those in MICT (heart rate, HIIT vs. MICT, p = 0.0005; SIT vs. MICT, p = 0.0015; lactate, HIIT vs. MICT, p = 0.0014; SIT vs. MICT, p = 0.0003). Arterial O2 saturation and arterial pH in HIIT and SIT were lower compared with MICT (SaO2, HIIT vs. MICT, p = 0.0035; SIT vs. MICT, p = 0.0265; pH, HIIT vs. MICT, p = 0.0011; SIT vs. MICT, p = 0.0023). Muscle glycogen content decreased significantly in HIIT (p = 0.0004) and SIT (p = 0.0016) immediately after exercise, but not in MICT (p = 0.19). Phosphorylation of AMP-activated protein kinase (AMPK) in HIIT showed a significant increase immediately after exercise (p = 0.014), but the increase was not significant in MICT (p = 0.13) and SIT (p = 0.39). At 4 h after exercise, peroxisome proliferator-activated receptor γ co-activator-1α mRNA increased in HIIT (p = 0.0027) and SIT (p = 0.0019) and vascular endothelial growth factor mRNA increased in SIT (p = 0.0002).DiscussionDespite an equal run distance, HIIT and SIT cause more severe arterial hypoxemia and lactic acidosis compared with MICT. In addition, HIIT activates the AMPK signaling cascade, and HIIT and SIT elevate mitochondrial biogenesis and angiogenesis, whereas MICT did not induce any significant changes to these signaling pathways.
Bee Assemblage in the Southern Chihuahuan Desert: The Role of Season, Year, and Trap Color in Abundance
Authors: Munguia-Soto Esteban O. , Golubov Jordan , Mandujano María C. 
Published: November 2023

Recognizing how populations fluctuate over time is a crucial factor in determining the environmental elements affecting population persistence. However, the limited information on wild bee populations complicates the estimation of the impact of anthropogenic threats leading to changes in population size. To address this, we conducted a study capturing and monitoring nine species of wild bees through monthly samplings over four years. Tray traps were placed in permanent plots, and capture records were used to determine population size (N) and density (D). A generalized linear model (GLM) was employed to determine how the use of traps affected bee species captures. The families Apidae and Halictidae represented the most captures. Apis mellifera, the Lasioglossum (Dialictus spp.) complex, and Macrotera sinaloana exhibited the largest number of captures and highest population density. Most species (77.7%) showed a tendency to remain constant over the years and to have a higher number of captures in the spring months. Moreover, yellow traps were the most effective in capturing bee individuals. We suggest that the availability of essential resources and the reduction in environmental stressors positively affected the capture of wild bee populations.
Adaptation to Telehealth of Personalized Group Visits for Late Stage Diabetic Kidney Disease
Authors: Drake Connor , Rader Abigail , Clipper Christie , Haney Malia , Bulgin Dominique , Cameron Blake , Kinard Tara , Sangvai Devdutta , Tomso Susan , Snyderman Ralph 
Published: November 2023

Key Points

Improving late stage diabetic kidney disease care requires adapting evidence-based, self-management programs for telehealth delivery.We adapted and pilot-tested a telehealth approach and found it to be feasible. Preliminary data suggested it improved relevant health and patient-recorded outcomes.

Background
The coronavirus disease 2019 pandemic resulted in an unprecedented shift in the delivery of outpatient medical care, including the rapid transition of services from in-person to telehealth. We adapted an evidence-based personalized health planning group visit care model traditionally offered in-person to telehealth to support the care of patients with type 2 diabetes mellitus (T2D) and CKD. Despite the need to leverage telehealth technologies to better support self-management for patients with CKD, scant evidence exists on how to do so.

Methods
We conducted prospective adaptations of in-person evidence-based group visit model for telehealth delivery for patients with CKD and T2D. Intervention adaptations are reported using the Framework for Reporting Adaptations and Modifications–Expanded taxonomy. The adapted virtual group visit care model was pilot-tested among adults with T2D and stage 3b or 4 CKD. Feasibility outcomes included recruitment, attendance, satisfaction, and self-reported goal progress. Clinical outcomes were evaluated using Wilcoxon signed-rank tests and included hemoglobin A1c, diastolic and systolic BP, body mass index, and eGFR.

Results
Adaptation areas included outreach, visit format, educational materials design and access, staffing, and patient engagement strategies. 39% (43) of patients (110) contacted verbalized interest, and 58% (25) of those participated. 72% completed >6 group sessions. 68% of patients reported completing one or more health goals, with nutrition and physical activity being the most common. We observed a statistically significant improvement in hemoglobin A1c (P = 0.0176) 6 months postprogram participation.

Conclusions
Adapting evidence-based interventions for telehealth delivery is challenging because of the risk of altering an intervention's core components responsible for observed benefits. We adapted an in-person group visit model for the care of T2D and CKD for telehealth delivery. The telehealth approach was feasible, and preliminary data suggested it improved relevant health and patient-recorded outcomes up to 6 months postprogram completion. The approaches used here may be applicable to the adaptation of other clinical programs for telehealth delivery.

Podcast
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Pre-recruiting HR marketing for new Gen talent acquisition: the mediating role of Word of Mouth
Authors: PANAGIOTIDOU SOFIA 
Published: November 2023

The purpose of this study is to investigate how, at the pre-recruitment stage, product brand awareness and publicity of a company affect the knowledge of the company's Employer Brand and the intention to apply for a job in this company. Furthermore, it will be investigated whether these associations are strengthened by the mediating effect of the positive Word of Mouth about the company as a desired employer. The Structural Equation Modeling (PLS-SEM) software was used on a sample of 737 students and recently graduates from Greek public universities. Overall, the findings of our research indicate the impact of a company's product/service brand awareness on the formulation of positive comments about the company as an employer. Indeed, product knowledge, when linked to company publicity initiatives and both are leveraged in a general pre-recruiting marketing plan of the HR department, positive Word of Mouth (WOM) commentary is enhanced. The information that job seekers receive from employees' feedback helps them to gain practical and useful details about the work conditions and the opportunities for training and personal development within it. Moreover, through the descriptions of the employee experience in the company the job seekers’ intention to search employment in this particular employer is strengthened.
Network governance in Healthcare, a systematic literature review
Authors: Maris Arjen , Hoppenbrouwers Stijn , Ravesteijn Pascal , Van Hillegersberg Jos 
Published: November 2023

The typical structure of the healthcare sector involves (specialist) intertwined practices co-occurring in formal or informal networks. These practices must answer to the concerns and needs of all related stakeholders. Multimorbidity and the need to share knowledge for scientific development are among the driving factors for collaboration in healthcare. To establish and keep up a permanent collaborative link, it takes effort and understanding of the network characteristics that must be governed.
It is not hard to find practices of Network Governance (NG) in a variety of industries. Still, there is a lack of insight in this subject, including knowledge on how to establish and maintain an effective healthcare network. Consequently, this study's research question is: How is network governance organized in the healthcare sector?
A systematic literature study was performed to select 80 NG articles. Based on these publications the characteristics of NG are made explicit. The findings demonstrate that combinations of governance style (relational versus contractual governance) and governance structure (lead versus shared governance) lead to different network dynamics. Furthermore, the results show that in order to comprehend how networks in the healthcare sector emerge and can be regulated, it is vital to understand the current network type. Additionally, it informs us of the governing factors.
How are Educators Taking the Next Steps in Leadership and Entrepreneurship
Authors: Benitez Garcia Antonio 
Published: November 2023

ABSTRACT
How are educators taking the next steps in leadership and entrepreneurship teaching concepts?
In recent years the development of leadership as a concept has taken different meanings in the educational field. The following paper will explain some practical approaches on how this concept it’s been addressed in the classroom and outside in a different environment, as well as the settings of these courses to better equip the students with full understanding on a particular subject.

Entrepreneurship has step up its game in fields that we were not used to see before. These entrepreneurial activities are directly linked with the leadership approach of an organization, start up, or school. Hence the importance of how to dive in into full understanding and delivery of the subject, not only through previous theories and proven concepts in particular organizations, but by the students putting themselves in a position of action, so that they can put in practice the knowledge applied.

The author will examine responses of the students in entrepreneurship and leadership courses, from a University in China, from different majors, where cultural variables may be applicable as well. The study will have a qualitative approach, which will shed some light in the current practices from students and academics approach to the delivery of these subjects, and how to create a better learning environment incorporating theory and action plan, considering their major program and path in their own school curriculum.

This paper aims to develop some understanding of innovative forms and approaches applied in Education, through the way of delivery some of the most important courses like Leadership and Entrepreneurship, since these courses could ultimately be applied to every sector of an industry.

Keywords: Leadership, Education, Entrepreneurship, Management, Studies, University, Approaches