bluuebunny/crossref_metadata_2025_split huggingface dataset:
Microvascular Response in the Periosteum Following Mucoperiosteal Flap Surgery in Dogs: Angiogenesis and Bone Resorption and Formation
Authors: Nobuto Takahiro , Suwa Fumihiko , Kono Tomoo , Taguchi Yoichiro , Takahashi Tsurayuki , Kanemura Naoko , Terada Shoichiro , Imai Hisao 
Published: August 2005

Background: When surgical stress reaches the periosteum, bone resorption and formation that occur as a periosteal response are closely related to angiogenesis and hemodynamics. Thus, we investigated bone remodeling in the healing process after mucoperiosteal flap surgery, focusing our attention on the microcirculation.Methods: Mucoperiosteal flap surgery was performed on 12 adult beagle dogs. The periosteal vascular plexus was observed on days 7, 14, 21, and 28 after surgery, using three different techniques: in histological specimens into which India ink was injected into blood vessels, under a light microscope; in ultrathin sections, using a transmission electron microscope; and in acryl plastic‐injected vascular corrosion cast specimens, under a scanning electron microscope.Results: On day 7 after surgery, the interstitum of the elevated mucoperiosteal vascular plexus was filled with sinusoidal new blood vessels. Bone resorption by osteoclasts was observed around these new blood vessels and many highly permeable fenestrations were present in the vascular endothelium. On day 14 after surgery, sinusoidal new blood vessels were more markedly developed and some regions exhibited glomeruluslike morphology consistent with bone resorption cavities. Activated osteoblasts were present around these new blood vessels and highly permeable vesicles, which were considered to be possible vesiclo‐vacuolar organelles (VVOs) and caveolae, were noted in the vascular endothelium. On days 21 and 28 after surgery, the mucoperiosteal vascular plexus was dissected through regression of endothelial cells and fibroblasts and reconstructed into a rough mesh structure, and simultaneously the bone surface became smooth.Conclusion: The morphology of the mucoperiosteal vascular plexus changed with bone metabolism and these changes contributed to transport of substances involved in periodontal repair. J Periodontol 2005;76:1346‐1353.
Progression of Experimental Chronic Peri‐Implantitis in Dogs: Clinical and Radiographic Evaluation
Authors: Martins Marilia Compagnoni , Shibli Jamil Awad , Abi‐Rached Ricardo Samih Georges , Marcantonio Elcio 
Published: August 2005

Background: The aim of this study was to evaluate the progression of experimental peri‐implantitis in dogs using implants with different surface coatings.Methods: Thirty‐six dental implants with four different surface coatings, commercially pure titanium (cpTi), titanium plasmasprayed (TPS), hydroxyapatite (HA), and acid‐etched (AE), were placed in six mongrel dogs. Five months after implantation, peri‐implantitis was induced by cotton ligatures to facilitate plaque accumulation for 60 days. After 60 days, the ligatures were removed and supragingival plaque control was initiated for 12 months. Probing depth (PD), clinical attachment level (CAL), vertical bone level (VBL), horizontal bone level (HBL), and mobility were obtained at baseline, and 20, 40, 60 (acute phase), and 425 days (chronic phase) after ligature removal.Results: PD and CAL changed around all implant surfaces after ligature placement (P <0.0001). However, the means of PD and CAL were not statistically significant among the different surfaces (P >0.05). The range of CAL variation, calculated between baseline and 60 days (acute phase) and between 60 and 425 days (chronic phase), decreased (P <0.05). Bone loss increased during the entire experiment (P <0.0001). The HA surface showed the greatest bone loss measurement (5.06 ± 0.38 mm) and the TPS showed the smallest bone loss (4.27 ± 0.62 mm). However, statistical significance was not assessed for different coatings (P >0.05).Conclusions: The clinical data at the initial phase showed rapid and severe peri‐implant tissue breakdown. However, removal of ligatures did not convert the acute destructive peri‐implant phase to a non‐aggressive lesion and the progression of peri‐implantitis was observed at chronic phase. The experimental peri‐implantitis in dogs may be a useful model to evaluate the progression of peri‐implantitis. J Periodontol 2005;76:1367‐1373.
Micro‐Raman Studies on DLC coatings
Authors: Irmer G. , Dorner‐Reisel A. 
Published: August 2005

AbstractRaman scattering is an excellent tool to characterize nanocrystalline clusters and the structural arrangement of carbon atoms in carbon‐based materials. Diamond‐like carbon (DLC) films are used in many industrial applications due to their hardness, wear resistance and biological compatibility. The properties of DLC coatings depend on the carbon coordination and incorporation of other elements, influences onto their Raman spectra will be reviewed.
A Critical Review of the Stress Corrosion Cracking (SCC) of Magnesium Alloys
Authors: Winzer N. , Atrens A. , Song G. , Ghali E. , Dietzel W. , Kainer K. U. , Hort N. , Blawert C. 
Published: August 2005

AbstractThis review aims to provide a foundation for the safe and effective use of magnesium (Mg) alloys, including practical guidelines for the service use of Mg alloys in the atmosphere and/or in contact with aqueous solutions. This is to provide support for the rapidly increasing use of Mg in industrial applications, particularly in the automobile industry. These guidelines should be firmly based on a critical analysis of our knowledge of SCC based on (1) service experience, (2) laboratory testing and (3) understanding of the mechanism of SCC, as well as based on an understanding of the Mg corrosion mechanism.
Cover Picture: An Investigation of the Inelastic Deformation of Cortical Bone (Adv. Eng. Mater. 8/2005)
Authors: Mercer C. , Wang R. , Evans A. G. 
Published: August 2005

AbstractThe cover picture shows shear bands that develop during compression of cortical bone. It shows that the bands extend across the bone lamellae and are mirror symmetric with respect to the loading axis. More on the inelastic deformation of cortical bone can be found in the paper By C. Mercer and A. G. Evans on page 719..
Enhanced Photocurrent Spectral Response in Low‐Bandgap Polyfluorene and C70‐Derivative‐Based Solar Cells
Authors: Wang X. , Perzon E. , Oswald F. , Langa F. , Admassie S. , Andersson M. R. , Inganäs O. 
Published: August 2005

AbstractPlastic solar cells have been fabricated using a low‐bandgap alternating copolymer of fluorene and a donor–acceptor–donor moiety (APFO‐Green1), blended with 3′‐(3,5‐bis‐trifluoromethylphenyl)‐1′‐(4‐nitrophenyl)pyrazolino[70]fullerene (BTPF70) as electron acceptor. The polymer shows optical absorption in two wavelength ranges, λ < 500 nm and 600 < λ < 1000 nm. The BTPF70 absorbs light at λ < 700 nm. A broad photocurrent spectral response in the wavelength range 300 < λ < 1000 nm is obtained in solar cells. A photocurrent density of 3.4 mA cm–2, open‐circuit voltage of 0.58 V, and power‐conversion efficiency of 0.7 % are achieved under illumination of AM1.5 (1000 W m–2) from a solar simulator. Synthesis of BTPF70 is presented. Photoluminescence quenching and electrochemical studies are used to discuss photoinduced charge transfer.
Neurodegenerative diseases of infancy and childhood
Authors: Dyken Paul , Krawiecki Nicolas 
Published: August 2005

AbstractThe neurodegenerative diseases of infancy and childhood include disorders in which there is progressive loss of neurological function due to structural abnormalities of the central nervous system. Well over six hundred disorders, many of which are rarely seen, can be included in this category. Yet, the conditions represent collectively over onefourth of all admissions to pediatric neurology services.Five‐year samples of admission characteristics of 1218 patients from two medical centers over twenty‐two years permit an estimate of the frequency of the neurodegenerative diseases. The six most‐encountered diagnoses, in declining order, were: subacute sclerosing panencephalitis; neuronal ceroid lipofuscinosis; tuberous sclerosis with degeneration; West disease, or idiopathic degenerative encephalopathy associated with infantile spasms; Werdnig‐Hoffmann disease, and hereditary spastic paraplegia.A classification is offered grouping the neurodegenerative disorders into five major categories: polioencephalopathies, leukoencephalopathies, corencephalopathies, spinocerebellopathies, and diffuse encephalopathies. Disorders in each subgroup may be either genetic or nongenetic. Neurodegenerative diseases have multiple causes, including metabolic, viral, immunopathic, environmental, and epileptogenic. The cause of many remains unknown.
Sequence of metabolic, clinical, and histological events in experimental thiamine deficiency
Authors: Hakim A. M. , Pappius H. M. 
Published: August 2005

AbstractThe {14C}deoxyglucose technique was used to determine local cerebral glucose utilization (LCGU) in the rat at varous times in two models of thiamine deficiency: pyrithiamine administration in addition to dietary deprivation, and dietary deprivation alone. In the pyrithiamine model most of the 40 structures examined showed a gradual decline in LCGU, reaching the lowest metabolic activity at day 11. A statistically significant rise in LCGU (p < 0.05) was then noted between day 11 and day 12 or 14 in 18 structures, followed by the autoradiographic appearance of focal areas of centrally depressed glucose utilization in many of these same 18 structures. Only then did ambulatory difficulty, opisthotonus, and other advanced clinical sequelae of thiamine deficiency become evident, usually around day 18, followed by the appearance of focal histological lesions in the same distribution. On a different time scale, rats that were only deprived of thiamine in their diet over a prolonged period, but not their pair‐fed controls, revealed the same metabolic and autoradiographic events, but the deprivation was not sufficiently prolonged to result in clinical or histological abnormalities. We believe that the selective rise in LCGU may set into motion a chain of events that leads to the subsequent clinical and histological consequences of thiamine deficiency.
Intermittent thiamine deficiency in the rhesus monkey. II. Evidence for memory loss
Authors: Witt Ellen D. , Goldman‐Rakic Patricia S. 
Published: August 2005

AbstractThiamine‐deprived rhesus monkeys exhibited a pattern of impairments in spatial‐reversal learning and in recognition of highly familiar items reminiscent of certain memory deficits shown by Wernicke‐Korsakoff patients. Postmortem examination in these experimental animals showed neuronal degeneration in the basal ganglia, the parafascicular nucleus of the thalamus, and discrete nuclei of the brainstem and cerebellum. No abnormalities were found in the mammillary bodies and mediodorsal nucleus of the thalamus, structures that have been incriminated in the genesis of the memory impairment of the Wernicke‐Korsakoff syndrome of man.
Acute panautonomic neuropathy
Authors: Low P. A. , Dyck P. J. , Lambert E. H. , Brimijoin W. S. , Trautmann J. C. , Malagelada J. R. , Fealey R. D. , Barrett D. M. 
Published: August 2005

AbstractTwo patients with acute panautonomic neuropathy had severe impairment of sympathetic and parasympathetic function of acute onset. Autonomic tests suggesting a postganglionic lesion and direct evidence of loss of unmyelinated and small myelinated fibers on nerve biopsy were found in Patient 1. There was a selective loss of small myelinated and unmyelinated nerve fibers; C potential was absent in the in vitro compound action potential; dopamine‐β‐hydroxylase activity was unmeasurable. No definite abnormalities were found on the nerve biopsy of Patient 2. The acute panautonomic neuropathies appear to comprise a spectrum of somatic and autonomic involvement.
Immunoregulatory T‐cells and lymphocytotoxic antibodies in active multiple sclerosis: Weekly analysis over a six‐month period
Authors: Hauser Stephen L. , Reinherz Ellis L. , Hoban Carolyn J. , Schlossman Stuart F. , Weiner Howard L. 
Published: August 2005

AbstractImmunoregulatory T‐cell subsets were measured at weekly intervals over a 4 to 6 month period using monoclonal antibodies (anti‐T4 = inducer cell; anti‐T8 = suppressor/cytotoxic cell) in a group of 6 patients with multiple sclerosis (MS) and in 4 age‐ and sex‐matched controls. Decreases in the T8 subset and increases in the T4: T8 ratio were present in 4 of the patients with MS but not in controls. Two patients who were neurologically stable during the study period had no changes in the T4: T8 ratio; 2 patients with intermediate disease activity of the relapsing‐remitting type had elevated ratios on 3 and 4 occasions respectively; the patient with the most clinically active MS had an abnormal ratio 12 of 27 times. One patient with chronic‐progressive MS had an elevated ratio on each occasion tested. No abnormalities in T‐cell subsets were present in any of the controls. On three occasions an elevated T4:T8 ratio appeared to precede an acute relapse by 1.5 to 7 days. Lymphocytotoxic antibodies (LCA) against whole lymphocytes or against isolated T‐cell subsets were measured in these patients and in a larger group of MS patients, and were not found to correlate with changes in T‐cell subsets. This report extends previous findings linking changes in T‐cell subsets to disease activity in patients with MS.
Permanent neurological deficits due to lithium toxicity
Authors: Apte Sateesh N. , Langston J. William 
Published: August 2005

AbstractTwo patients exhibited permanent neurological deficits following relatively uncomplicated episodes of lithium intoxication. Lithium toxicity alone appears to result in a fairly consistent combination of neurological findings, including deficits in recent memory, limb and truncal ataxia, and choreoathetosis or parkinsonism. The potential role of early hemodialysis in preventing these permanent deficits is discussed.
Familial paroxysmal dystonic choreoathetosis and response to alternate‐day oxazepam therapy
Authors: Kurlan Roger , Shoulson Ira 
Published: August 2005

AbstractA patient with familial paroxysmal dystonic choreoathetosis (FPDC) who was only transiently improved on daily benzodiazepine therapy showed sustained benefit from a regimen of alternate‐day oxazepam therapy. Our findings confirm that FPDC is responsive to benzodiazepine therapy and suggest that an alternate‐day dosing schedule, using a short‐acting benzodiazepine, may minimize receptor down regulation and thereby sustain the therapeutic effect.
Progressive CT abnormalities despite clinical improvement in SSPE treated with inosiplex
Authors: Noetzel Michael J. , Dodson W. Edwin 
Published: August 2005

AbstractInosiplex has been utilized in the treatment of subacute sclerosing panencephalitis (SSPE), though without unequivocally established beneficial effect. We report a patient whose computerized tomographic (CT) scans demonstrated the development of progressive cerebral atrophy and multifocal white matter lesions despite continuous treatment with inosiplex and periods of considerable clinical improvement or stabilization. The findings suggest that inosiplex may not have altered the pathological consequences of SSPE and that clinical staging categories alone may not be reliable long‐term correlates of the progression of the disease. Controlled studies utilizing assessment of brain mass by CT scan or other imaging devices in addition to clinical staging are required to evaluate the efficacy of inosiplex.
Analgesic activity of tricyclic antidepressants
Authors: Spiegel Katharyn , Kalb Robert , Pasternak Gavril W. 
Published: August 2005

AbstractAmitriptyline (median effective dose {ED50} 1.2 mg per kilogram of body weight), imipramine (ED50 2.3 mg/kg), and their demethylated derivatives nortriptyline (ED50 1.9 mg/kg) and desimipramine (ED50 3.2 mg/kg) are active analgesics as indicated by the mouse writhing assay. Although not as potent as morphine (ED50 0.2 mg/kg), the antidepressants were up to 70 times more potent than aspirin (ED50 91 mg/kg). The actions of amitriptyline were not affected by the specific opiate antagonist naloxone but were markedly attenuated in animals whose monoamine levels had been depleted with reserpine. Central mechanisms appear important since amitriptyline (ED50 4.6 μg) was potent when administered intracerebroventricularly.
Maternal diseases and isolated orofacial clefts in Hungary
Authors: Métneki Júlia , Puhó Erzsébet , Czeizel Andrew E. 
Published: August 2005

AbstractBACKGROUNDIsolated orofacial clefts (OFCs) are likely to be caused by gene‐environment interaction; therefore, the objective of the current study was to evaluate the possible association between all maternal diseases during pregnancy and isolated cleft lip with or without cleft palate (CL ± CP) and posterior cleft palate (PCP) in the offspring.METHODSThe database of the large population‐based Hungarian Case‐Control Surveillance of Congenital Abnormalities, 1980–1996, was evaluated. The database includes 1374 cases with isolated CL ± CP and 601 with PCP, plus 38,151 matched population controls (without defects) and 20,868 patient controls with other defects. Data collection was based on prospective medical records, retrospective maternal data via a self‐reported questionnaire, and home visits of nonresponding families.RESULTSAn increased risk for isolated CL ± CP was found for children born to mothers with influenza, common cold, orofacial herpes, and gastroenteritis during pregnancy. Risk for isolated PCP was increased in children of mothers with influenza, sinusitis, and bronchitis. Among chronic maternal diseases, epilepsy and angina pectoris showed a higher prevalence in the mothers of children born with isolated OFCs (cases).CONCLUSIONSSome maternal diseases are risk factors for the pathogenesis of isolated OFCs. It is worth considering the prevention of possible harmful effects of influenza by vaccination during the expected epidemic period. Birth Defects Research (Part A), 2005. © 2005 Wiley‐Liss, Inc.
Electrochemical Synthesis of Dendritic Polyaniline in Brønsted Acid Ionic Liquids
Authors: Bao‐You Liu , Dan‐Qian Xu , Zhen‐Yuan Xu 
Published: August 2005

AbstractBrønsted acid ionic liquids were successfully applied to the electrochemical synthesis of polyaniline films on platinum electrode surfaces by using cyclic voltammetry. The scanning electron micrographs showed distinct changes in morphological structures. The films exhibited quite dense packing and good ordering of polymer dendrite as compared with those prepared using conventional hydrochloric acid, indicating that Brønsting acid ionic liquids might be promising alternatives to dual medium‐dopants in the synthesis of conducting polymers.
Potential of Eigen Value Method to the Study on Structure‐antioxidant Activity Relationship
Authors: De‐Xin Kong , Tao Jiang , Hua‐Shi Guan 
Published: August 2005

AbstractAntioxidants are of great interest because of their involvement in many important biological and industrial processes. It is meaningful to study their structure‐antioxidant activity relationship (SAAR) and design novel, efficient and low‐toxicity antioxidant. In this paper, Eigen Value Analysis (EVA), a 3‐dimensional quantitative structure activity relationship (3‐D QSAR) method, was employed to study antioxidant SAAR. Significant relational models were obtained with all the PLS cross‐validate $q^{2}_{cv} $ values being larger than 0.5, meaning that the models have sound predictive power. Compared with other QSAR methods, EVA possesses several advantages, especially that it does not need alignment. It should be believed that EVA will be an efficient approach to SAAR.
Thermodynamic Study on the Azeotropic Mixture Composed of Ethanol and Toluene
Authors: Zhao‐Dong Nan , Zhi‐Cheng Tan , Jun Xing 
Published: August 2005

AbstractThe molar heat capacity of the azeotropic mixture composed of ethanol and toluene was measured by a high precision adiabatic calorimeter from 80 to 320 K. The glass transition and phase transitions of the azeotropic mixture were determined based on the heat capacity measurements. A glass transition at 103.350 K was found. A solid‐solid phase transition at 127.282 K, two solid‐liquid phase transitions at 153.612 and 160.584 K were observed, which correspond to the transition of metastable crystal to stable crystal of ethanol and the melting of ethanol and toluene, respectively. The thermodynamic functions and the excess ones of the mixture relative to the standard temperature 298.15 K were derived based on the relationships of the thermodynamic functions and the function of the measured heat capacity with respect to temperature.
Full Non‐Rigid Group and Symmetry of Dimethyltrichloro‐phosphorus
Authors: Ali Reza Ashrafi 
Published: August 2005

AbstractIn this work, a simple method is described, by means of which it is possible to calculate character tables for the symmetry group of molecules consisting of a number of NH3 groups attached to a rigid framework. The full non‐rigid group (f‐NRG) of dimethyltrichlorophosphorus with the symmetry group D3h was studied. It has been proven that it is a group of order 216 with 27 conjugacy classes and its character table computed. Finally, thePermutation‐Inversion group of this molecule was calculated.
Study on the Crystal Structure of a Macrocycle and Tyrosinase Activity of Its Dinuclear Copper Complexes
Authors: Hong Zhou , Zhi‐Quan Pan , Qin‐Hui Luo , Guang‐Quan Mei , De‐Liang Long , Jiu‐Tong Chen 
Published: August 2005

AbstractA ring‐contracted form macrocycle, 29,30‐dioxo‐3,6,9,17,20,23,29,30‐octaazapentacyclo[23,3,1,111,15,02,6,016,20]‐triacontaneocta‐1(28),9,11(12),13,15(30),23,25(29),26‐ene (L) was synthesized by condensation of diethyltriamine with pyridine‐1‐oxide‐2,6‐dicarboxaldehyde. A porous three‐dimensional layer structure in its crystal was formed by self‐assembly through hydrogen bonds and π‐π interaction. Its dinuclear copper(I) complex [Cu2L(MeOH)2](BF4)2·2H2O and dinuclear‐copper(II) complex [Cu2L(MeOH)2](ClO4)4·2H2O were obtained and could oxidize catalytically four phenolic substrates hydroquinone, 2‐methyl‐hydroquinone, 2,6‐di‐tert‐butylphenol and 2,6‐dimethylphenol, in a mixture of methanol and acetonitrile (V:V, 4:1). The copper(I) complex reacted with dioxygen to form an oxygenated species as an initial active intermediate for oxidation of the phenols. Oxidation of the substrates by the copper(II) complex produced a copper(I) complex and the oxidation products of the substrates.
Characterization and Crystal Structure of Tris(N′‐ethyl‐N‐piperazinyl‐carbodithioato‐s,s′)cobalt(III) Complex: Co(S2CNC4H8NC2H5)3·3H2O
Authors: Ying Wang , Lian‐He Yan 
Published: August 2005

AbstractThe title compound has been prepared and characterized by elemental analyses, infrared and NMR spectra, and thermal analyses. The crystal and molecular structure of tris(N′‐ethyl‐N‐piperazinly‐carbodithioato‐s,s′)cobalt(III) complex, Co(S2CNC4H8NC2H5)3·3H2O, was determined by X‐ray diffraction methods. The compound crystallizes in trigonal system, space group R‐3, with lattice parameters a=1.37700(19) nm, b=1.37700(19) nm, c=3.0090(6) nm, γ=120°, Mr=680.98, V=4.9411(14) nm3, Z=6, Dc=1.373 g/cm3, F(000)=2160, R=0.0510 and wR=0.1436. In the structure, central Co atom coordination geometry is slightly distorted octahedron with the six S atoms from the three bidentate S2CNC4H8NC2H5 ligands. The octahedron is distorted resulting from forced configuration of the four‐membered chelate ring. The six CoS bond distances are in the range of 0.22682(13)‐0.22703(14) nm. The IR and NMR spectral data are in agreement with the structural data. The thermal analytical data indicate that it decomposed completely at the temperature of 799.97 °C, leaving CoS.