bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of providing EFL learners with additional online and face‐to‐face practise opportunities to promote active learning in higher education
Authors: Liu Jingrong , Li Shujun , Zhang Wanfang 
Published: January 2024

AbstractBackgroundLimited research on the effectiveness of additional online and face‐to‐face practise opportunities for promoting active learning among Chinese EFL learners in higher education. Current understanding of self‐regulated and collaborative learning theories in educational contexts.ObjectivesTo establish the efficacy of interactive online and face‐to‐face practise opportunities for enhancing active learning among Chinese EFL learners.MethodsEmployed mixed methods research to assess the impact of different types of practise opportunities on 116 EFL learners. Utilised methodological triangulation of QUAN + QUAL data and one‐way ANOVA for interpretation.Results and conclusionsThe study demonstrated the effectiveness of integrating online and face‐to‐face practise opportunities to enhance active learning. Empirical evidence supports the pedagogical and theoretical benefits of these opportunities for promoting active learning among EFL learners.
Predictors and barriers to engagement in caring for children with a mental health diagnosis: A qualitative study of caregivers perception of power
Authors: Seney Valerie 
Published: January 2024

AbstractBackgroundEvidence‐based treatments used in managing behaviors of children require caregiver engagement. However, there is a gap in understanding a caregiver's level of comprehension of how they can advocate for their children's mental health needs and how to help their children in the home once outpatient treatment is initiated.MethodsThis was a qualitative study using interviews with semi‐structured research questions. Recruitment was through convenience sampling at a private practice mental health agency. Nine participants were interviewed. A thematic analysis was completed posttranscription and coding.ResultsFour themes emerged that captured the lived experience of the caregivers as they sought to facilitate care for the child/adolescent: Feeling lost (powerless navigating the mental health care system); Feeling a loss of control (Lack of Return Communication and Lack of Available Providers); Feeling frustrated (insurance and/or cost barriers); and Feeling powerless to help (their child at home and not included in treatment).RelevanceThis study addresses the gaps in the current health care system. Through examining the caregiver's sense of power in their role in mental health care for their children, interventions may be developed to encourage more active involvement in treatment outcomes and more involvement in interventions for the home setting. Moreover, this study highlights the importance of giving insight to providers on how to help families navigate mental health care, communicate more, and include the patient and caregiver in the development of comprehensive treatment plans.
Tax‐loss selling and the January effect revisited: Evidence from municipal bond closed‐end funds and exchange‐traded funds
Authors: Carrion Allen , Zhang Jiang 
Published: January 2024

AbstractWe revisit the tax‐loss selling hypothesis as an explanation for the January effect. We expand on prior empirical evidence from municipal bond closed‐end funds (CEFs) by extending the sample period by 19 years and adding exchange‐traded funds (ETFs). Our sample covers the introduction and rapid growth of municipal bond ETFs, significant changes to municipal bond market structure, and the modernization of tax‐loss selling practices. The January effect in municipal bond CEFs has become stronger in recent years and is consistent with the tax‐loss hypothesis. The January effect in municipal bond ETFs is smaller and cannot be explained by tax‐loss selling.
Informed trading by hedge funds
Authors: Huang Qiping , Jain Pankaj K. 
Published: January 2024

AbstractUsing daily equity transactions, we create a hedge fund informed trading measure (ITM) that separates concentrated information‐related trades from liquidity‐driven basket trades. We find that stocks with higher ITM are associated with higher future stock performance. The long–short portfolio delivers 4% annual alpha after controlling for size, value, momentum, and illiquidity factors. We attribute informed trading to hedge funds' ability to identify and correct stock underpricing. The results are robust to several ways of constructing and sorting the measure, and we do not find a return reversal in four quarters, indicating that the measure is information related.
Efficacy of serious games for chronic pain management in older adults: A systematic review and meta‐analysis
Authors: Saragih Ita Daryanti , Suarilah Ira , Saragih Ice Septriani , Lin Yen‐Ko , Lin Chia‐Ju 
Published: January 2024

AbstractAims and ObjectivesTo synthesise and appraise the evidence of the efficacy of serious games in reducing chronic pain among older adults.BackgroundChronic pain in older adults generally results in a substantial handicap due to decreased mobility, exercise avoidance and various concerns that affect their overall quality of life. While serious games have been widely used as a pain management approach, no reviews have thoroughly examined their efficacy for chronic pain management in older adult populations.DesignA systematic review and meta‐analysis.MethodsThe CINAHL, the Cochrane Library, Embase, Medline, PubMed and Web of Science databases were comprehensively searched to find articles published from their inception until 17 April 2023. RoB‐2 was used to assess the risk of bias in the included studies. The efficacy of serious games for pain management in older individuals was investigated using pooled standardised mean differences (SMDs) in pain reduction using a random effect model.ResultsThe meta‐analysis comprised nine randomised controlled trials that included 350 older adult patients with pain. Serious games effectively alleviated pain in this group (pooled SMD = −0.62; 95% confidence interval: −1.15 to −0.10), although pain‐related disability and fear require further investigation.ConclusionsSerious games tended to effectively reduce pain in this older adult group; however, due to a lack of randomised controlled trials, the analysis found lower effectiveness in reducing pain‐related disability and fear. Further studies are accordingly required to confirm these findings.Relevance to Clinical PracticeThe findings of the study emphasise the importance of serious games to increase the motivation of older adults to exercise as one of the safe and extensively used pain management strategies. Serious games that effectively reduce chronic pain in older adults are characterised as consisting of diverse physical activities delivered through consoles, computer‐based activities and other technologies.Patient or Public ContributionsSerious games are recommended as being potentially useful and practical for reducing pain in older adults.
Changes in belongingness, meaningful work, and emotional exhaustion among new high‐intensity telecommuters: Insights from pandemic remote workers
Authors: Afota Marie‐Colombe , Provost Savard Yanick , Léon Emmanuelle , Ollier‐Malaterre Ariane 
Published: January 2024

AbstractThe COVID‐19 pandemic has thrust millions of workers into high‐intensity telecommuting. While much research has examined the first months of the pandemic, little is known about how workers have responded to this new work arrangement over time. The stressor‐reaction perspective suggests that any strain related to the physical separation from coworkers may persist as long as the stressor is present, while the adaptation perspective implies that individuals adopt new behaviours that help them adjust once the initial shock is over. This research examines the changes in work belongingness, meaningful work, and emotional exhaustion following a shift to high‐intensity telecommuting, between September 2020 and March 2021. We conducted a four‐wave study among an organizational sample of 716 workers who transitioned to high‐intensity telecommuting during the pandemic. Latent growth modelling analyses showed that new high‐intensity telecommuters experienced declines in work belongingness over time, which in turn led to decreased perceptions that their work was meaningful and increased emotional exhaustion, supporting the stress‐reaction perspective. Contrary to theoretical predictions, trajectories were worse for those with a higher initial affective commitment to coworkers. We discuss how our findings can inform scholars and practitioners about the unfolding consequences of a collective shift to high‐intensity telecommuting.
B12 deficiency‐related glossitis is highly associated with high gastrin‐17 and low pepsinogen I
Authors: Zhu Jingci , He Yining , Feng Huang , Wang Yufeng , Ge Zili 
Published: January 2024

AbstractBackgroundThe causes of vitamin B12 (B12) deficiency are varied and mainly related to gastric disorders. Glossitis is a common oral manifestation of B12 deficiency and is often first seen by dentists. This study aimed to investigate the correlation between B12 deficiency‐related glossitis (B12‐def glossitis) and gastric serum biomarkers [gastrin‐17(G17), pepsinogen I (PGI), pepsinogen II (PGII), and anti‐Helicobacter pylori (H. pylori) antibodies], and preliminarily discuss the etiology of B12‐def glossitis.MethodsA cross‐sectional study was conducted in patients complaining of glossodynia, burning sensation, or severe recurrent oral ulcers, but patients with a history of gastrectomy were excluded. All subjects underwent a uniform oral examination and hematological tests.ResultsOf 243 patients, 133 with B12‐def glossitis were in the case group, and 110 with other oral mucosal diseases (non‐glossitis) and normal B12 levels were in the control group. In the case group, 84.2% (112/133) showed high G17 and low PGI levels (G17hi PGIlow). Univariate logistic regression showed that G17hi PGIlow was a high‐risk factor for B12‐def glossitis (OR: 92.44; 95% CI: 35.91, 238.02). Subgroup analyses in the case group showed that the G17hi PGIlow group presented with lower B12 levels and a lower positive rate of anti‐H. pylori antibodies compared to the non‐G17hi PGIlow group.ConclusionGastric serum biomarkers in patients with B12‐def glossitis generally showed G17hi PGIlow, suggesting possible atrophy of gastric corpus and fundus mucosa. The G17hi PGIlow and non‐G17hi PGIlow groups may represent different etiologies of B12 deficiency.
Binding and unbinding of potent melatonin receptor ligands: Mechanistic simulations and experimental evidence
Authors: Bedini Annalida , Elisi Gian Marco , Fanini Fabiola , Retini Michele , Scalvini Laura , Pasquini Silvia , Contri Chiara , Varani Katia , Spadoni Gilberto , Mor Marco , Vincenzi Fabrizio , Rivara Silvia 
Published: January 2024

AbstractThe labeled ligand commonly employed in competition binding studies for melatonin receptor ligands, 2‐[125I]iodomelatonin, showed slow dissociation with different half‐lives at the two receptor subtypes. This may affect the operational measures of affinity constants, which at short incubation times could not be obtained in equilibrium conditions, and structure–activity relationships, as the Ki values of tested ligands could depend on either interaction at the binding site or the dissociation path. To address these issues, the kinetic and saturation binding parameters of 2‐[125I]iodomelatonin as well as the competition constants for a series of representative ligands were measured at a short (2 h) and a long (20 h) incubation time. Concurrently, we simulated by molecular modeling the dissociation path of 2‐iodomelatonin from MT1 and MT2 receptors and investigated the role of interactions at the binding site on the stereoselectivity observed for the enantiomers of the subtype‐selective ligand UCM1014. We found that equilibrium conditions for 2‐[125I]iodomelatonin binding can be reached only with long incubation times, particularly for the MT2 receptor subtype, for which a time of 20 h approximates this condition. On the other hand, measured Ki values for a set of ligands including agonists, antagonists, nonselective, and subtype‐selective compounds were not significantly affected by the length of incubation, suggesting that structure–activity relationships based on data collected at shorter time reflect different interactions at the binding site. Molecular modeling simulations evidenced that the slower dissociation of 2‐iodomelatonin from the MT2 receptor can be related to the restricted mobility of a gatekeeper tyrosine along a lipophilic path from the binding site to the membrane bilayer. The enantiomers of the potent, MT2‐selective agonist UCM1014 were separately synthesized and tested. Molecular dynamics simulations of the receptor–ligand complexes provided an explanation for their stereoselectivity as due to the preference shown by the eutomer at the binding site for the most abundant axial conformation adopted by the ligand in solution. These results suggest that, despite the slow‐binding kinetics occurring for the labeled ligand, affinity measures at shorter incubation times give robust results consistent with known structure–activity relationships and with interactions taken at the receptor binding site.
Hepatitis C virus reinfection incidence among gay and bisexual men with HIV in Australia from 2016 to 2020
Authors: Harney Brendan L. , Sacks‐Davis Rachel , van Santen Daniela K. , Traeger Michael W. , Wilkinson Anna L. , Asselin Jason , Fairley Christopher K. , Roth Norman , Bloch Mark , Matthews Gail V. , Donovan Basil , Guy Rebecca , Stoové Mark , Hellard Margaret E. , Doyle Joseph S. 
Published: January 2024

AbstractBackgroundThere is some concern that hepatitis C virus (HCV) reinfection might impact HCV micro‐elimination efforts among gay and bisexual men (GBM) with HIV. However, there is a limited understanding of reinfection incidence in the context of unrestricted government‐funded HCV treatment. We aimed to estimate HCV reinfection incidence among GBM with HIV in Australia from 2016 to 2020.MethodsData were from 39 clinics participating in ACCESS, a sentinel surveillance network for blood borne viruses and sexually transmissible infections across Australia. GBM with HIV who had evidence of treatment or spontaneous clearance with at least one positive HCV RNA test, a subsequent negative HCV RNA test, and at least one additional HCV RNA test between 1st January 2016 and 31st December 2020 were eligible for inclusion. A new HCV RNA positive test and/or detectable viral load was defined as a reinfection. Generalised linear modelling was used to examine trends in reinfection.ResultsAmong 12 213 GBM with HIV who had at least one HCV test, 540 were included in the reinfection incidence analysis, of whom 38 (7%) had evidence of reinfection during the observation period. Over 1124 person‐years of follow‐up, the overall rate of reinfection was 3.4/100PY (95% CI 2.5–4.6). HCV reinfection incidence declined on average 30% per calendar year (Incidence Rate Ratio 0.70, 95% CI 0.54–0.91).ConclusionHCV reinfection incidence has declined among GBM with HIV in Australia since government‐funded unrestricted DAAs were made available. Ongoing HCV RNA testing following cure and prompt treatment for anyone newly diagnosed is warranted to sustain this.
Adherence to the Eatwell Guide and population and planetary health: A Rank Prize Forum report
Authors: Shannon Oliver M. , Townsend Rebecca , Malcomson Fiona C. , Matu Jamie , Griffiths Alex , Jennings Amy , Ward Nicola , Papier Keren , Best Nicola , French Chloe , Scheelbeek Pauline , Kim Curie , Ochieng Bertha , Jay Fareeha , Shepherd Kaydee , Corfe Bernard , Fairley Andrea , McEvoy Claire T. , Minihane Anne‐Marie , Sim Yi Jia , Stevenson Emma , Gregory Sarah 
Published: January 2024

AbstractThis report summarises a Forum conducted in June 2023 to explore the current state of the knowledge around the Eatwell Guide, which is the UK government's healthy eating tool, in relation to population and planetary health. The 1.5‐day Forum highlighted the limited, albeit promising evidence linking higher adherence to the Eatwell Guide with favourable health outcomes, including reduced overall mortality risk, lower abdominal obesity in post‐menopausal women and improved cardiometabolic health markers. Similarly, evidence was presented to suggest that higher adherence to the Eatwell Guide is associated with reduced greenhouse gas emissions. Presentations were given around cultural adaptations of the Eatwell Guide, including African Heritage and South Asian versions, which are designed to increase the acceptability and uptake of the Eatwell Guide in these communities in the United Kingdom. Presentations highlighted ongoing work relevant to the applications of the Eatwell Guide in randomised controlled trials and public health settings, including the development of a screening tool to quantify Eatwell Guide adherence. The Forum ended with a World Café‐style event, in which the strengths and limitations of the Eatwell Guide were discussed, and directions for future research were identified. This Forum report serves as a primer on the current state of the knowledge on the Eatwell Guide and population and planetary health and will be of interest to researchers, healthcare professionals and public health officials.
Staff‐based measurement instruments of person‐centredness in settings of care for older people: A systematic review
Authors: Elfstrand Corlin Tinna , Kazemi Ali 
Published: January 2024

AbstractBackgroundPerson‐centred care is widely endorsed as a promising approach for delivering high‐quality care to older people. However, the multitude of existing definitions and measurement tools, coupled with the continuous emergence of new tools, can create confusion and hinder precision in assessing this concept. This review was undertaken with a recognition of the crucial role that assessment quality plays in evaluations and improvements, particularly within the context of person‐centred care for older people.ObjectivesThis study aimed to systematically review staff‐based measures of person‐centredness in settings of care for older people. More specifically, the objectives were to provide description, methodological evaluation and synthesis of diverse conceptual understandings of person‐centredness encapsulated in these measurement tools.MethodsWe systematically searched the Cinahl, PsycInfo, PubMed, Scopus and Web of Science databases for English peer‐reviewed journal articles between 2000 and 2021. These articles discussed the creation of staff‐based questionnaires designed to assess the extent of person‐centred care. We excluded questionnaires meant for clients, patients or families, as well as non‐questionnaire scales. The measures were described, and their interpretations of person‐centred care were synthesised through a critical interpretive synthesis method. We evaluated methodological quality using a condensed COSMIN risk of bias checklist and adhered to PRISMA guidelines.ResultsThe review identified a total of 14 staff‐based measures. These measures exhibited varying levels of comprehensiveness, encompassing anywhere between 2 and 17 components. Furthermore, the number of items within the measures ranged from 11 to 62, and the sample sizes exhibited significant diversity, spanning from 58 to 1428. In terms of the components scrutinised by the scales regarding person‐centred care, our synthesis revealed the emergence of four distinct conceptual categories: care process, supportive care environment, relations and communication, and knowledge and attitudes. As for the methodological quality of the scales, it exhibited a notable degree of variation (i.e. from inadequate to very good).ConclusionsDiverse measures of person‐centredness vary in terms of comprehensiveness, aspects covered and methodological quality. Synthesising the concept through staff‐based measures offers a novel approach for researchers and practitioners, illuminating nuanced perspectives in person‐centred care.Implications for practiceThe synthesis enriches academic discussions and practical applications by dissecting components, ultimately enhancing care quality assessment and improvement. Further, this review is a valuable resource for unit managers and quality coordinators working in settings of care for older people, empowering them to make informed decisions tailored to their specific needs from a diverse array of available person‐centred care measures.
Pain characterization in patients with Parkinson's disease
Authors: Nogueira Ana Carolinne Rodrigues , Pereira Karyne Corrêa , Rodrigues Vinício Ferreira , Alves Danielle De Paula Aprígio , Marques Juliana Bittencourt , Monteiro Estêvão Rios , Jesus Igor Ramathur Telles De 
Published: January 2024

AbstractBackgroundPatients with Parkinson's disease (PD) often report chronic pain, which is one of the most complex non‐motor symptoms. Therefore, this study aims to review the literature on the characteristics of pain in patients with PD.MethodsA systematic literature review was conducted following MOOSE recommendations. Observational studies reporting pain in patients with PD were included. No time restrictions were applied, but studies in Portuguese, Spanish, and English were considered. The search was performed in PubMed®, LILACS, and SciELO databases.ResultsTwenty‐six articles of observational studies were identified, reporting an average pain prevalence of 67.36%, emphasizing the significance of this symptom in the PD population. Pain was reported in various body regions, including lower limbs, upper limbs, lumbar spine, cervical spine, and other joints. Pain classification varied, encompassing musculoskeletal pain, PD‐related pain, neuropathic pain, and dystonic pain, among others.DiscussionPain in patients with PD is a prevalent and multifactorial condition, significantly impacting patients' quality of life.ConclusionHeterogeneity in data across included studies was observed, highlighting the need for additional research to elucidate the underlying mechanisms of pain in patients with PD and develop effective therapeutic strategies to address this symptom and improve the quality of life for individuals living with the disease.