bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health literacy-related knowledge, attitude, perceived barriers, and practice among primary care doctors in Malaysia
Authors: Mohamed-Yassin Mohamed-Syarif , Daher Aqil M. , Ramli Anis Safura , Ramli Nabilah Farhana , Baharudin Noorhida 
Published: November 2023

AbstractThis study aimed to assess the health literacy (HL) related knowledge, attitude, perceived barriers, and practice among primary care doctors (PCDs) in Malaysia, and to determine the factors associated with HL-related practice. A cross-sectional study was conducted using an online questionnaire. Sociodemographic and work-related details were collected. HL-related knowledge, attitude, perceived barriers, and practice were assessed. Descriptive and inferential analyses using linear regression were performed. 373 PCDs were included in the study with a mean (SD) age of 37.9 (8.1) years old. The mean (SD) HL-related knowledge, attitude, and practice scores were 6.89 (1.27), 36.33 (7.04), and 30.14 (4.7), respectively. 90.9% of the participants had good HL-related knowledge scores, and 89.5% had positive HL-related attitude. More than 80% of participants found that “time constraint to implement health literacy screening” and “lack of human resources to administer HL screening tools in their settings” were among the barriers for them to implement HL practices. PCDs of Chinese and other ethnicities had lower HL-related practice scores compared to those of Malay ethnicity (adjusted b = − 1.74; 95% CI − 2.93, − 0.54, and − 2.94; 95% CI − 5.27, − 0.60, respectively). PCDs who had heard of the term “health literacy” were associated with higher HL-related practice scores (adjusted b = 2.32; 95% CI 1.17, 3.47). Age (adjusted b = 0.10; 95% CI 0.04, 0.16) had significant linear positive relationship with HL-related practice. In conclusion, the HL-related knowledge, attitude, and practice among PCDs in Malaysia were at an acceptable level. Along with educating PCDs on HL, the perceived barriers identified need to be addressed to improve the HL-related practice and ultimately patient care.
A large-scale integrated vector–matrix multiplication processor based on monolayer molybdenum disulfide memories
Authors: Migliato Marega Guilherme , Ji Hyun Goo , Wang Zhenyu , Pasquale Gabriele , Tripathi Mukesh , Radenovic Aleksandra , Kis Andras 
Published: November 2023

AbstractData-driven algorithms—such as signal processing and artificial neural networks—are required to process and extract meaningful information from the massive amounts of data currently being produced in the world. This processing is, however, limited by the traditional von Neumann architecture with its physical separation of processing and memory, which motivates the development of in-memory computing. Here we report an integrated 32 × 32 vector–matrix multiplier with 1,024 floating-gate field-effect transistors that use monolayer molybdenum disulfide as the channel material. In our wafer-scale fabrication process, we achieve a high yield and low device-to-device variability, which are prerequisites for practical applications. A statistical analysis highlights the potential for multilevel and analogue storage with a single programming pulse, allowing our accelerator to be programmed using an efficient open-loop programming scheme. We also demonstrate reliable, discrete signal processing in a parallel manner.
Molecular dissection of the soluble photosynthetic antenna from the cryptophyte alga Hemiselmis andersenii
Authors: Rathbone Harry W. , Laos Alistair J. , Michie Katharine A. , Iranmanesh Hasti , Biazik Joanna , Goodchild Sophia C. , Thordarson Pall , Green Beverley R. , Curmi Paul M. G. 
Published: November 2023

AbstractCryptophyte algae have a unique phycobiliprotein light-harvesting antenna that fills a spectral gap in chlorophyll absorption from photosystems. However, it is unclear how the antenna transfers energy efficiently to these photosystems. We show that the cryptophyte Hemiselmis andersenii expresses an energetically complex antenna comprising three distinct spectrotypes of phycobiliprotein, each composed of two αβ protomers but with different quaternary structures arising from a diverse α subunit family. We report crystal structures of the major phycobiliprotein from each spectrotype. Two-thirds of the antenna consists of open quaternary form phycobiliproteins acting as primary photon acceptors. These are supplemented by a newly discovered open-braced form (~15%), where an insertion in the α subunit produces ~10 nm absorbance red-shift. The final components (~15%) are closed forms with a long wavelength spectral feature due to substitution of a single chromophore. This chromophore is present on only one β subunit where asymmetry is dictated by the corresponding α subunit. This chromophore creates spectral overlap with chlorophyll, thus bridging the energetic gap between the phycobiliprotein antenna and the photosystems. We propose that the macromolecular organization of the cryptophyte antenna consists of bulk open and open-braced forms that transfer excitations to photosystems via this bridging closed form phycobiliprotein.
Known mechanisms cannot account for a third of reduced susceptibility in non-aureus staphylococci
Authors: Felgate Heather , Crossman Lisa C. , Gray Elizabeth , Clifford Rebecca , Correia Annapaula , Dean Rachael , Wain John , Langridge Gemma C. 
Published: November 2023

AbstractNon-aureus staphylococci (NAS) are implicated in many healthcare-acquired infections and an understanding of the genetics of antimicrobial resistance is important in relation to both clinical intervention and the role of NAS as a reservoir of resistance genes. Gap statement: The burden of antimicrobial resistance in NAS, particularly to clinically relevant antimicrobials, is under-recognised. We sourced 394 NAS isolates from clinical samples, healthy human volunteers, animals and type cultures and subjected them to minimum inhibitory concentration (MIC) testing by agar dilution using eight antimicrobials. Cefoxitin was used to screen for methicillin resistance, as it stimulates the expression of mecA in S. aureus. We performed whole genome sequencing on 366 isolates and analysed these genotypically for the presence of genetic mechanisms responsible for the phenotypic levels of reduced antimicrobial susceptibility. We observed 175 sequenced isolates with a MIC ≥ 4 µg/ml to cefoxitin, of which 50% did not harbour a known mec homologue. Eight clinical NAS isolates displayed high daptomycin MICs (>4 µg/ml), with no known mechanism identified. Differences in MICs against erythromycin were attributable to the presence of different resistance genes (msrA and ermC). In total, 49% of isolates displayed reduced susceptibility to three or more of the antimicrobials tested. The widespread presence of reduced antimicrobial susceptibility in NAS is concerning. An increased likelihood of harder-to-treat infections caused directly by NAS with acquired resistance genes has clinical implications for AMR detection, the horizontal resistance gene pool and the management of patients.
Non‐fungible token‐based health record marketplace
Authors: Kumar Valli S , Lee John J. , Hu Qin 
Published: November 2023

AbstractWith an increasing affinity towards patient‐centric care, sharing real‐time sensitive data for collaboration between multiple parties with finer access control becomes critical. Most existing studies based on the blockchain technology in the medical field discuss various application scenarios and security aspects, without focusing on data ownership, secure data sharing, or finer access control. In this work, a non‐fungible token (NFT)‐based system is proposed to implement a health record marketplace. The system leverages the NFT technology to provide dual ownership along with finer access control and efficiency in data sharing. The advantage of permissioned blockchain along with InterPlanetary File System (IPFS) are taken for off‐chain data storage to improve security and efficiency. Because price determination is critical in the market, Stackelberg game theory is utilized to determine pricing strategies for both data owners and consumers. Also, to efficiently achieve finer access control, a popularity‐based adaptive NFT management scheme using reinforcement learning is proposed. Simulation experiments are carried out to demonstrate accuracy and efficiency of our proposed schemes.
A selection principle of submodule switching state vectors for switching frequency reduction in voltage self‐balancing half‐bridge modular multilevel converters
Authors: Zhou Yiyuan , Qin Liang , Yang Shiqi , Wang Qing , Liu Kaipei 
Published: November 2023

AbstractThe problem of submodule switching frequency reduction in half‐bridge modular multilevel converters (HB‐MMCs) with capacitor voltage self‐balancing control is considered and explored in this paper. A selection principle of submodule switching state vectors is proposed based on the voltage self‐balancing switching state matrix, aiming to lower submodule switching frequency and device losses. The relationship between system stability and submodule switching signals is revealed according to the capacitor voltage self‐balancing characteristics, and the full‐rank constraints on the voltage self‐balancing switching state matrix are proposed. Considering the tradeoff between switching loss and capacitor voltage fluctuation, the evaluation indexes of voltage self‐balancing control effect are determined. The selection principle of submodule switching state vectors and the optimized construction method of switching state matrix are presented. Voltage self‐balancing HB‐MMC models are built in MATLAB/Simulink, and it is verified that the submodule switching state vector selection principle proposed in this study can effectively reduce switching frequency while meeting the evaluation requirements of practical engineering projects, so as to achieve the balance between switching loss and steady‐state capacitor voltage fluctuation.
Integrierte Tierärztliche Bestandsbetreuung und Selektives
Trockenstellen in Deutschland
Authors: Sonnewald-Daum Tanja , Obster Fabian , Mansfeld Rolf 
Published: November 2023

Zusammenfassung
Ziel Ermittlung von aktuellen Informationen über Entwicklung und
Durchführung der Integrierten Tierärztlichen Bestandsbetreuung
(ITB) sowie Verbreitung des Selektiven Trockenstellens (ST) in deutschen
Tierarztpraxen und Milchviehbetrieben. Zudem Darstellung von Unterschieden oder
Gemeinsamkeiten zwischen Tierärzten mit und ohne ITB in Bezug auf die
Anwendung von Verfahren zum ST.
Material und Methoden 600 Fragebögen wurden im Rahmen von 7
Fortbildungen an Nutztierpraktiker verteilt. Die Teilnahme war freiwillig und
anonym. Die Datenauswertung erfolgte mittels deskriptiver Statistik, linearer
und logistischer Regression.
Ergebnisse Der Rücklauf betrug 39,3% (n=236). Eine
ITB wurde von 54,2% (n=128) der Tierärzte
durchgeführt. Von 75% (n=177) der Tierärzte
wurden Verfahren zum ST angewendet. Dabei wurden verschiedene
Entscheidungskriterien auf Herden- (81,6%, n=142) und
Einzeltierebene (97,7%, n=172) genutzt. Eine Erfolgskontrolle
des Verfahrens wurde häufiger in Betrieben von Tierärzten mit
ITB (66%, n=66) als ohne ITB (41%, n=28)
durchgeführt. Je mehr Betriebe im Rahmen einer ITB betreut wurden, desto
höher war der Anteil der Betriebe, in denen selektiv trockengestellt
wurde. Eine steigende Chance auf eine gleichbleibende oder verbesserte
Eutergesundheit war mit ST-Betrieben assoziiert, in denen gleichzeitig eine ITB
durchgeführt wurde (OR: 1,025; p<0,05). Die Beratung bei
Problemen in der Trockenstehzeit (OR: 3,639; p<0,05), die
Häufigkeit, mit der Tierärzte die Landwirte (OR: 1,595;
p<0,05) und Landwirte die Tierärzte auf ST ansprachen (OR:
1,538; p<0,05), sowie die Beratungshäufigkeit zum
Trockenstellmanagement (OR:1,608; p<0,05) hatten einen positiven
Einfluss auf die Wahrscheinlichkeit, ob ST in einem Betrieb durchgeführt
wurde und ob dies erfolgreich war.
Schlussfolgerungen Sowohl ITB als auch ST sind nach vorliegenden Daten
etablierte Bestandteile der tierärztlichen Tätigkeit in
Rinderpraxen. Das ST wird in der Praxis zum Teil im Rahmen kontrollierter
Verfahren mit Erfolgskontrolle umgesetzt. Die Durchführung einer ITB war
positiv mit der Anzahl der Betriebe assoziiert, in denen selektiv
trockengestellt wurde, und mit dem Eutergesundheitsstatus, wenn in einem Betrieb
ITB und ST kombiniert durchgeführt wurden. Beratungsangebot und
-häufigkeit der Tierärzte haben einen wesentlichen Einfluss auf
eine Antibiotikareduktion durch ST.
Total removal of the fourth metacarpal bone in an Icelandic
horse
Authors: Vidović Aleksandar , Kuhn Sabrina 
Published: November 2023

AbstractFractures of the splint bones are the most common fractures in horses. Various
treatment options for splint bone fractures (MC/MT II and IV), including
conservative and surgical management, have been described. This report describes
an acute splint bone fracture due to external trauma in a 17-year-old Icelandic
mare. The fracture was diagnosed as an open multifragment fracture of the
proximal third of the fourth metacarpal bone (MCIV) in the right front limb.
Surgery was performed with the horse under general anaesthesia. The distal
fragments were removed, and the distal part of the proximal remnant splint bone
was cut with an osteotome. During the postoperative period, a routine
x-ray-control two days after surgery showed a dislocated fracture of the
remaining proximal part of the fourth metacarpal bone. In a second surgery, the
proximal part of MCIV was entirely removed. After a reconvalescence period of 5
month, the horse reached her previous level of performance as a leisure horse.
The mare is still free of lameness 6 years after the incident.
Reactions of 5-(Trialkyl)silylpent-1-en-4-yn-3-ones with Hydrazines: Original Synthetic Routes to Luminescent Substances Containing Azole Motifs
Authors: Golovanov Alexander A. , Odin Ivan S. , Gordon Kareem V. , Itakhunov Radik N. , Gusev Dmitry M. , Sokov Sergey A. , Vologzhanina Anna V. , Grabovskiy Stanislav A. , Sosnin Ilya M. , Ukolov Anton I. , Orlova Olga I. , Lazarenko Vladimir A. , Dorovatovskii Pavel V. , Darmoroz Darina D. , Piven Anastasiia O. , Orlova Tetiana 
Published: November 2023

AbstractOn the basis of the selective reactions of hydrazines with trialkylsilyl-substituted cross-conjugated enynones (pent-1-en-4-yn-3-ones) as fundamental building blocks, this work presents the developed common methodology for the synthesis of polysubstituted luminescent derivatives of acetylenic pyrazolines, pyrazoles, and combined polyheterocycles containing structural fragments from pyrazolines, isoxazoles, thiophenes, thiazoles, benzo[d]thiazoles, and benzo[d]imidazoles. In reactions with hydrazine and its monosubstituted aromatic and heteroaromatic derivatives, the mentioned pent-1-en-4-yn-3-ones, containing Me3Si, Et3Si, and t-BuMe2Si groups at the triple bond, give 3-(trialkylsilyl)ethynylpyrazolines. Following stages of desilylation and 1,3-dipolar cycloaddition with nitrile oxides, the 3-(trialkylsilyl)ethynylpyrazolines provide the formation of combined polyheterocyclic derivatives. Thus, a one-pot synthetic route to pyrazoline-containing isoxazoles from cross-conjugated enynones, arylhydrazines, and α-chlorobenzaldoximes has been developed. Some aspects of cyclocondensation mechanism and luminescent properties of synthesized azoles derivatives were examined.
Polarization-insensitive silicon optic switch based on mode manipulated power splitters and phase shifters
Authors: Zhao Shi , Chen Jingye , Dai Daoxin , Shi Yaocheng 
Published: November 2023

A polarization-insensitive thermo-optic switch is proposed and demonstrated on the silicon-on-insulator platform with a 220 nm silicon core layer. The present device is based on the Mach–Zehnder interferometer structure, consisting of polarization-insensitive power splitters and polarization-insensitive phase shifters (PIPSs). The polarization-insensitive power splitter has been realized by employing an adiabatic directional coupler, which utilizes the fast adiabatic mode evolution by introducing cubic Bézier curves on outer contours, providing broadband 3-dB power splitting for TE and TM polarization modes with only 70 µm coupling length. For the novel PIPSs, the ridge waveguide with large aspect ratio, based on the mode hybridness property, could obtain the same power consumption (Pπ) for an optical switch working at TE and TM polarizations. Experimental results indicate that the measured insertion losses are less than 2 dB and the extinction ratios are larger than 15 dB over a 40 nm wavelength band (covering the C-band).
Translating gender in video games
Authors: Martínez Pleguezuelos Antonio Jesús 
Published: November 2023

Abstract
This article investigates the role of localization in the representation of different gender and sexuality
profiles in video games. Using Sara Ahmed’s queer phenomenology as a methodological framework, it analyzes the ideological and
cultural limitations that restrict the rewriting of minority sexualities and genders when the original versions are transferred to
other languages. The article begins by considering the generative capacities of translation as an agent that can discursively
construct the subject, before focusing on the implications of localization for the shaping of identities from a phenomenological
perspective to describe what conditions may lead to the appearance of translated queer paradigms in video games. The theoretical
approach is applied to selected examples and conclusions for the practice of localization and its academic study are drawn.
High sensitivity refractive index sensor based on double peanut-shaped and etched multimode fiber structures
Authors: Wei Huijing , Wang Fang , Wang Xu , Liu Yufang 
Published: November 2023

Abstract
A fiber optic refractive index (RI) sensor based on an etched multimode fiber (MMF) with a double peanut-shaped structure is proposed and experimentally demonstrated. The sensor consists of two peanut-shaped and a section of etched MMF tapered fiber structure. The excitation of the fundamental mode to higher-order modes is facilitated by using the beam splitting/coupling effect of the double peanut-shaped and etched taper structures, and the higher-order modes can be excited into an evanescent field. In the sensing medium, the stronger the evanescent field, the stronger the energy shock between the fiber and the sensing environment. Experimental results showed that the sensitivity was 326.52 nm/RUI and 823.91 nm/RUI when the etched waist taper diameter was 51.92 μm and the glycerol solution index ranged from 1.3395 to 1.3945 and 1.3945 to 1.4200, respectively. Compared to the MMF sensor structure without etching, the RI sensitivity is improved by about 2 times. In addition, the temperature characteristics of the sensor were investigated over a range of 30 °C–100 °C, and the results showed a maximum temperature sensitivity of only 30.24 pm °m−1. The sensor structure has a low-temperature sensitivity and the temperature effect on the RI measurement results is negligible within the allowable error range. The sensor has the advantages of simple fabrication, wide measurement range, good stability, low cost, and compact structure, which has potential application value in the field of RI detection.
Development of an analytical method for the determination of pesticides in tropical fruits by LC-QTOF-MS/MS after QuEChERS extraction sample cleanup and DLLME preconcentration
Authors: Sel Sabriye , Er Elif Öztürk , Koyuncu İkbal 
Published: November 2023

Abstract
In this study, QuEChERS extraction was combined with dispersive liquid–liquid microextraction (DLLME) to extract pesticides from tropical fruits for determination by a highly accurate and sensitive liquid chromatography-quadrupole time-of-flight mass spectrometry (LC-QTOF-MS/MS) system. The QuEChERS method served as a matrix clean-up tool and the DLLME method preconcentrated the analytes for their determination at trace levels. All parameter variables of the DLLME method were optimized to improve the extraction output and lower the limits of detection and quantification (LOD and LOQ) for all the analytes. Under the optimum experimental conditions, the LOD and LOQ values were found in the range of 0.004–0.013 and 0.27–0.61 μg l−1, respectively. The detection limits achieved by direct LC-QTOF-MS/MS analysis were increased by about 10–260 folds using the optimized DLLME method. To assess the accuracy and applicability of the developed method, spike recovery experiments on tropical fruits were carried out. The matrix matching calibration method was used to enhance the quantification accuracy of the analytes in kiwi, pineapple, and mango matrices, with percent recoveries ranging between 89 and 117%.
A multicentre retrospective study of lumbar sympathectomy for plantar hyperhidrosis: satisfaction and postoperative complications
Authors: Housset Marie , Dessertenne Grégory , Marchand Etienne , Daligault Mickaël , Maillard Hervé 
Published: November 2023

Abstract

Background
Primary plantar hyperhidrosis has a severe impact on quality of life and conservative treatments are only effective in the short term. Thoracic sympathectomy has proven its effectiveness in the treatment of palmar hyperhidrosis, but lumbar sympathectomy for plantar hyperhidrosis remains poorly described.

Objectives
To report the satisfaction of patients with primary plantar hyperhidrosis treated with mechanical lumbar sympathectomy as well as their postoperative complications.

Methods
This was a multicentre retrospective observational study of 16 patients with primary plantar hyperhidrosis, treated with mechanical lumbar sympathectomy from December 2012 to October 2022. Patients’ characteristics were collected from medical records. Quality of life, postoperative satisfaction and complications were evaluated using a standardized questionnaire.

Results
Lumbar sympathectomy was performed on 16 patients, 14 were women and 2 were men with a total of 31 procedures. Fourteen (88%) patients were satisfied and would recommend the surgery to other patients. Compensatory hyperhidrosis occurred in 75% of patients, recurrence of hyperhidrosis in 31% and sexual dysfunction in 19%.

Conclusions
Lumbar sympathectomy provides satisfying results for plantar hyperhidrosis with acceptable postoperative complications, regardless of sex. Compensatory hyperhidrosis was the most frequent complication but had no impact on patient satisfaction. In the literature, data on the risk of sexual dysfunction are reassuring and in our study only one of two men experienced transient ejaculation disorder.
Rachel Cusk’s New Realism: Gender, Power, Voice, and Genre in the Outline Trilogy
Authors: Holland Mary K 
Published: November 2023

Abstract
Rachel Cusk creates a new narrative form in the Outline trilogy—distanced, displaced first-person point of view—to create a safe position from which to speak truths about marriage and motherhood that she has been criticized for expressing in her nonfiction work. Eschewing linear plot and dominating perspective in favor of overheard stories, the novels also represent a new form of social realism that illustrates how listening and collaborative storytelling can communicate social critique. By incorporating elements of her life and nonfiction in the trilogy, Cusk creates a nexus of autobiography, fiction, essay, and memoir in which the suffering of women and the cruelty of misogyny register as visible and undeniably real, changing the fabric of social reality by rewriting the forms that represent it.