bluuebunny/crossref_metadata_2025_split huggingface dataset:
Econometric modeling of tobacco exports in the milieu of changing global and national policy regimes: repercussions on the Indian tobacco sector
Authors: Reddy K. Viswanatha , Paramesha V. , Kumar K. N. Ravi , Asci S. , Immanuelraj T. K. , Madhav M. Sheshu , Sendhil R. , Konduru S. , Rao K. Prabhakara , Ramasundaram P. 
Published: January 2024

IntroductionTobacco, an important commercial crop, plays a crucial role in farmers' incomes and livelihoods to a sizable population and contributes significant exchange earnings to the Indian economy. Currently, India is the second-largest tobacco producer after China, with a production of 758 million kg (13% of global production) and exports of ~190 million kg of tobacco (9% of global tobacco export volume). However, there are uncertainties surrounding the tobacco sector, such as growing public health and environmental issues associated with tobacco production and consumption and changing national and international tobacco-related policy regimes. In this context, the current study investigates the determinants of tobacco exports and geographical shifts in export destinations over the years.MethodsThe statistical models employed are co-integration, and vector error-correlation models to test the short-run and long-run dynamics relationship between tobacco exports and the explanatory variables, and the Markov chain approach to find out geographical shifts in export destinations.Results and discussionThe econometric model estimated the relationship between the tobacco export volume with domestic production, export price, and global demand for Indian tobacco, and investigated the geographical shift in export destinations of tobacco in the context of changing global and national policy regimes on the sector. The econometric modeling framework confirms that there exists a statistically significant relationship between Indian tobacco export demand, domestic production, export price, and world demand for Indian tobacco. The geographical shift was evident in major export destinations during the post-WHO-FCTC (Framework Convention on Tobacco Control) regime. The model findings direct that India should take advantage of the export price, and global demand for tobacco as India ratified WHO-FCTC; there is no scope for horizontal expansion of the area under tobacco. This modeling framework aids as a tool to direct and explore the possible options with a greater emphasis on export-centric farming system in tobacco production by augmenting crop compliance and quality to meet the standards of international markets.
“Early intervention isn't an option, it's a necessity”: learning from implementation facilitators and challenges from the rapid scaling of an early intervention eating disorders programme in England
Authors: Hyam Lucy , Torkelson Claire , Richards Katie , Semple Amy , Allen Karina L. , Owens Jill , Jackson Aileen , Semple Laura , Glennon Danielle , Di Clemente Giulia , Schmidt Ulrike 
Published: January 2024

IntroductionThe First Episode Rapid Early Intervention for Eating Disorders (FREED) service has shown promising outcomes for young people with an eating disorder, leading to national scaling and implementation across England. Between 2020 and 2023, the national implementation of FREED was supported by the Academic Health Science Networks (AHSNs), which are publicly funded organisations with the mission to spread innovations at scale and pace. This study aimed to investigate the views and experiences of AHSN programme leads on the national roll-out of FREED and the perceived sustainability of the model.Methods and resultsSemi-structured interviews were conducted with 13 programme leads across the AHSNs with direct experience supporting the national implementation of FREED. Thematic analysis was adopted using a critical realist approach. Initial sub-themes were inductively generated and then organised under seven larger themes representing the domains of the Non-adoption, Abandonment, and Challenges to Scale-Up, Spread and Sustainability (NASSS) framework. Each sub-theme was classified as a facilitator and/or barrier and then each larger theme/domain was assessed for its complexity (simple, complicated, complex). Data analysis revealed 28 sub-themes, 10 identified as facilitators, 13 as barriers, and five as both. Two domains were classed as simple, three as complicated, and two as complex. Sub-themes ranged from illness-related complexities to organisational pressures. Key facilitators included a high-value proposition for FREED and a supportive network. Key barriers included staffing issues and illness-related factors that challenge early intervention.DiscussionParticipants described broad support for FREED but desired sustained investment for continued provision and improving implementation fidelity. Future development areas raised by participants included enlarging the evidence base for early intervention, increasing associated training opportunities, and widening the reach of FREED. Results offer learning for early intervention in eating disorders and the scaling of new health initiatives.
Glucose Concentration in Regulating Induced Pluripotent Stem Cells Differentiation Toward Insulin-Producing Cells
Authors: Wang Chencheng , Abadpour Shadab , Olsen Petter Angell , Wang Daxin , Stokowiec Justyna , Chera Simona , Ghila Luiza , Ræder Helge , Krauss Stefan , Aizenshtadt Aleksandra , Scholz Hanne 
Published: January 2024

The generation of insulin-producing cells from human-induced pluripotent stem cells holds great potential for diabetes modeling and treatment. However, existing protocols typically involve incubating cells with un-physiologically high concentrations of glucose, which often fail to generate fully functional IPCs. Here, we investigated the influence of high (20 mM) versus low (5.5 mM) glucose concentrations on IPCs differentiation in three hiPSC lines. In two hiPSC lines that were unable to differentiate to IPCs sufficiently, we found that high glucose during differentiation leads to a shortage of NKX6.1+ cells that have co-expression with PDX1 due to insufficient NKX6.1 gene activation, thus further reducing differentiation efficiency. Furthermore, high glucose during differentiation weakened mitochondrial respiration ability. In the third iPSC line, which is IPC differentiation amenable, glucose concentrations did not affect the PDX1/NKX6.1 expression and differentiation efficiency. In addition, glucose-stimulated insulin secretion was only seen in the differentiation under a high glucose condition. These IPCs have higher KATP channel activity and were linked to sufficient ABCC8 gene expression under a high glucose condition. These data suggest high glucose concentration during IPC differentiation is necessary to generate functional IPCs. However, in cell lines that were IPC differentiation unamenable, high glucose could worsen the situation.
Tecnologias atuais para a segurança pública no estado do Paraná
Authors: Neppel Marcio Rogério 
Published: January 2024

Inicialmente, cabe expor que a Polícia Militar do Estado do Paraná desempenha um papel de extrema importância na segurança e no bem-estar da população paranaense, de maneira que a sua atuação abrangente, que vai desde o policiamento ostensivo até o apoio em situações de emergências, contribui para a prevenção de crimes, a redução da criminalidade e a promoção da paz na comunidade. Logo, é inegável a importância da PMPR para a construção de uma sociedade mais segura e harmoniosa. Mais precisamente quando se está diante da segurança pública, trata-se de um tema que desperta grande interesse e preocupação na sociedade, eis que perfaz um meio de salvaguardar os demais direitos das pessoas, como a liberdade e a vida. Diante disso, torna-se indiscutível que a atuação da Polícia Militar do Paraná (PMPR) ganha destaque, pois é responsável por garantir a ordem e a tranquilidade no estado. Nesse enfoque, como meio de auxiliar a Polícia Militar do Estado do Paraná a alcançar resultados satisfatórios quanto à segurança pública, o emprego dos meios tecnológicos vem se mostrando um assunto bastante importante, razão pela qual será analisado a partir deste momento.
Cumhuriyet Dönemi Mimarlarından Mimar Mukbil Kemal Taş ve Isparta-Senirkent Turan İlköğretim Okulu
Authors: KILIÇ Serkan 
Published: January 2024

Erken Cumhuriyet Dönemi’nde ulusal bütünlüğün sağlanmasında etkili olan en önemli alanlardan biri de mimari çalışmalardır. 1923-1930 yılları arasında ağırlık kazanan mimari oluşumlar, Birinci Ulusal Mimarlık Akımı üslubunda inşa edilmiştir. Ulusal mimari bilincin oluşmasında, Türk mimarlar ile birlikte yabancı mimarların da önemli katkıları olduğu bilinmektedir. Mimar Kemalettin Bey, Vedat Tek ve Arif Hikmet Bey ile aynı dönemde yaşamış Mukbil Kemal Taş, özellikle kamu yapıları içerisinde yer alan eğitim binaları alanında önemli projelere imza atmışlardır. Bu projeler sadece başkentle sınırlı kalmayıp il, ilçe ve köylerde de yansıma bulmuştur.
Cumhuriyet’in erken dönemlerinde Anadolu’nun birçok yerinde ibtidai mektepleri kurulmuştur. Senirkent’teki bölge ahalisinin politik tavrı, okul isminin ilerleyen yıllarda Turan ismini almasında da etkili olmuştur. Anadolu’nun pek çok yerinde benzer isimlendirmeler yapıldığı gibi günümüzde hala Kahramanmaraş, Kayseri, İzmir ve Van’da Turan İlkokulu ismi kullanılmaktadır.
1928 yılı itibariyle inşa edilmeye başlanan Turan İlköğretim Okulu’nun inşaat sürecinde olduğu gibi inşa edilen yapının planında da Anadolu’nun pek çok şehrinde bulunan ilk mekteplerle büyük bir benzerlik bulunmaktadır. Bu çalışmada, Cumhuriyet Dönemi mimarlarından olan ve Mimar Kemalettin’in ekibinde yer alan Mukbil Kemal Taş’ın, tasarlamış olduğu Isparta-Senirkentte’ki Turan İlköğretim Okulu’nun Ulusal Mimarlık ölçeğinde yorumlanması ve özellikle Mimar Kemalettin’in Mukbil Kemal Taş üzerindeki etkilerinin mimariye nasıl yansıdığı ele alınacaktır.
Ultra-low power low-dropout linear regulator with a load current tracking bias current generator for loT devices
Authors: Mizuno Yosuke , Sebe Hikaru , Kanemoto Daisuke , Hirose Testuya 
Published: January 2024

Abstract
This paper presents an ultra-low power low-dropout (LDO) linear regulator with a load current tracking bias current generator (BCG). The proposed LDO employs the load current tracking BCG to achieve stable and ultra-low power operation. The measurement results demonstrated that the proposed LDO produced a 1.2 V output and achieved 78 nA quiescent current, 145 mV mA−1 load regulation, and 2.2 mV V−1 line regulation.
Surface and interface mechanical properties of inorganic nanolayers
Authors: Huang Chia-Wei , Lai Tang-Yu , Fang Te-Hua 
Published: January 2024

Abstract
This study investigates the effects of the indenter on nickel coated by MoS2 during nanoindentation and nanoscratch through molecular dynamics simulations. The effects of indenter size, indenter shape, and scratch angle on the deformation and wear mechanisms of the material were studied. The results show that the size and shape of the indenter have significant effects under nanoindentation and scratching. A larger indenter size can lead to a larger deformation zone and more dislocations inside the workpiece, and the friction coefficient also decreases as the radius of the indenter increases. The friction coefficient at different scratch angles is not significantly different, indicating that in the monolayer of MoS2 coating, it is weakly dependent on the lattice orientation. In addition, different indenter shapes will cause differences in stress concentration and penetration depth inside the workpiece. The trapezoidal indenter also shows a higher friction coefficient and wear rate.
KOLERASI STATUS SOSIAL EKONOMI TERHADAP KEJADIAN KARIES GIGI ANAK TK BINA PUTRA II SUKARAME PALEMBANG
Authors: Wahyuni Sri , Nurhayati Masayu Nurhayati , Septiana Rika Septiana 
Published: January 2024

ABSTRAK
Latar Belakang: Status sosial ekonomi merupakan salah satu faktor yang mempengaruhi status kesehatan, Perilaku hidup sehat dapat dipengaruhi oleh sosial ekonomi yaitu pekerjaan, pendapatan. Pekerjaan menunjukan Status sosial ekonomi karna dari bekerja segala kebutuhan dapat terpenuhi. Status sosial ekonomi dapat mempengaruhi, gaya hidup, dan akses terhadap informasi dan pelayanan kesehatan.
Metode: Menggunakan metode deskriptif analitik dengan sampel penelitian berjumlah 44 reponden terdiri dari orang tua dan anak TK bina putra II
Hasil: Orang tua yang memiliki status sosial ekonomi katagori Rendah 13,6%, Sedang .72,8%. Tinggi 13,6%. Dan anak yang memiliki karies gigi (def-t) katagori rendah 36,4%,sedang 50%,dan tinggi 13,6%. Berdasarkan uji statistik Chi Square di peroleh nilai P =0,021( <0,05).
Kesimpulan: Adanya hubungan yang signifikat antara status sosial ekonomi dengan karies gigi pada anak bina putra II sukarami palembang.
PENGARUH PEMBERIAN BONEKA BERSUARA TERHADAP TINGKAT KECEMASAN PASIEN ANAK YANG AKAN DILAKUKAN PENCABUTAN GIGI
Authors: Hanum Nur Adiba 
Published: January 2024

Latar belakang. Di klinik Eksodonsia Jurusan Kesehatan Gigi Palembang, sering dijumpai pasien usia anak yang pada saat datang bersikap biasa, namun begitu mendengar bahwa giginya akan dicabut, seketika menunjukkan rasa cemas dan ketakutan yang pada akhirnya anak ingin pulang. Tujuan. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh permainan boneka bersuara terhadap tingkat kecemasan pasien anak yang akan dilakukan pencabutan gigi. Metode: Rancangan Penelitian adalah quasi eksperimental semu dengan pendekatan one group pretest and post test. Sampel adalah pasien usia 7-10 tahun yang berobat di klinik eksodonsia Jurusan Kesehatan Gigi Poltekkes Palembang, sebanyak 30 responden. Tingkat kecemasan diukur dengan skala ukur Hamilton Anxiety Rating Scale (HRS-A). Analisa data dilakukan menggunakan uji T berpasangan dengan CI 95% dan α < 0,05. Hasil penelitian ini didapatkan P = 0.00, artinya ada perbedaan secara signifikan antara tingkat kecemasan responden sebelum diberikan boneka bersuara dan setelah diberikan boneka bersuara pada responden yang akan dilakukan pencabutan gigi. Kesimpulan Pemberian boneka bersuara pada anak yang akan dilakukan pencabutan gigi berpengaruh menurunkan tingkat kecemasan anak secara signifikan.
A ASSISTÊNCIA ODONTOLÓGICA DE PACIENTES COM TRANSTORNO DO ESPECTRO AUTISTA
Authors: Santos Milena Ferreira dos , Mélo Mariana Almeida Gomes de , Lima Ana Cléa Aguiar de Araújo , Santos Maria Eduarda Ferreira Dos , Dias Leonardo dos Santos 
Published: January 2024

O transtorno do espectro autista (TEA) é um distúrbio do neurodesenvolvimento definido por desenvolvimento atípico, manifestações comportamentais, deficiência na comunicação e na interação social, padrões de comportamento repetitivos. Esse estudo consiste em uma revisão de literatura narrativa e foi desenvolvido a partir de uma análise documental da produção bibliográfica obtida através das bases de dados Pubmed e Scielo. Os critérios para inclusão dos estudos foram: artigos publicados entre os anos de 2012 a 2023; escritos nas línguas portuguesa e inglesa. Artigos publicados em inglês foram traduzidos para a avaliação posterior. O medo e os traumas serão sempre um obstáculo para a interferência odontológica presente no tratamento de crianças e adultos, com ou sem necessidades especiais, o que dificulta ainda mais o dentista a colocar em prática suas habilidades. Técnicas de condicionamento ou até mesmo abordagem multidisciplinar em crianças portadoras do TEA, o padrão a ser seguido é sempre o acolhimento, envolvimento da família, condicionamento comportamental e psicológico. Desta forma, foi possível entender que o tratamento odontológico para pacientes com TEA, é fundamental e possível desde que o profissional esteja devidamente capacitado, tendo uma abordagem adequada e diferenciada para cada um.
MANEJO EFICIENTE DE DESAFIOS EM CIRURGIAS DE EXTRAÇÃO DE TERCEIROS MOLARES
Authors: Oliveira Mirlly da Silva , Costa Maria Taywri Almeida , Torres Sandy de Azevedo , Júnior Nery José de Oliveira , Loss Andressa de Oliveira , Abreu Lucas Rafael Lobato , Novaes João Victor de Sá , Braga José Antônio Carvalho , Araujo Eduardo de Medeiros , Lopes Welton Vicente , Barreto Ronny Santos Araújo , Neto Pedro dos Santos , Loures Vitor Bedim , Becheleni Marco Túllio 
Published: January 2024

A extração do terceiro molar, é uma intervenção cirúrgica comum na odontologia, porém pode apresentar desafios devido à anatomia complexa que a região pode vim apresentar. Complicações durante ou após o procedimento podem variar de desconforto temporário a problemas mais sérios. OBJETIVO: Este estudo visa explorar estratégias de manejo eficiente desses desafios, destacando a importância da avaliação prévia e do planejamento cirúrgico e aplicações de tecnologias. METODOLOGIA: Realizou-se uma revisão abrangente de literatura, utilizando PubMed e Google Acadêmico, com termos como "Terceiro molar", "dentes impactados" e "complicações cirúrgicas". A seleção criteriosa considerou a contribuição à pesquisa e a confiabilidade, com Lakatos e Marconi (2017) sendo referências-chave. A análise incluiu apenas artigos em língua portuguesa para garantir interpretação precisa. DISCUSSÃO: Os fatores de risco, como posição anatômica, idade do paciente e condições sistêmicas, foram identificados como cruciais. Complicações pós-cirúrgicas, relacionadas à inflamação e infecção, demandam análise prévia para determinar a necessidade de antibioticoterapia. A revisão abordou a importância da anamnese, exames de imagem e protocolos de assepsia Novas tecnologias, como CBCT, impressão 3D, lasers de diodo e ultrassom. CONCLUSÃO: O estudo conclui que a extração do terceiro molar demanda uma abordagem cuidadosa e preventiva. A identificação de fatores de risco, a aplicação de estratégias preventivas e o uso de tecnologias inovadoras são fundamentais para o sucesso da cirurgia.
Integrando Práticas Psiquiátricas no Cuidado Multidisciplinar do TEA
Authors: Muniz Ana Paula Mendes Duarte , Rocha Maria Eduarda de Sá Bonifácio , Araújo Bianca Almeida Pessoa Rodrigues de , Périco Nathan Arenas , Zanatta Giulia , Santos Letícia Justino dos , Oliveira Neto Raimundo Franklin de , Tavares Yuji Atarashi , Martin Isabella Frauches , Carvalho Ana Carolina Sá de Souza , Lima Bruno Rocha de 
Published: January 2024

Introdução: O Transtorno do Espectro Autista (TEA) é uma condição neuropsiquiátrica que afeta principalmente a comunicação social, o comportamento e a interação social. Dessa forma, é de extrema relevância que a abordagem no cuidado e tratamento do TEA seja através de uma equipe multidisciplinar, incluindo profissionais de saúde mental, educadores e terapeutas, visando atender às necessidades específicas de cada indivíduo no espectro. Objetivo: Investigar os impactos da integração de práticas psiquiátricas no cuidado multidisciplinar do Transtorno do Espectro Autista (TEA), visando compreender as correlações entre intervenções psiquiátricas, evolução clínica e qualidade de vida. Metodologia: Foram utilizadas as bases de dados Pubmed, Cochrane e Scielo, buscando artigos publicados entre os anos 2020 a 2023, nos idiomas Português ou Inglês. Considerações finais: Ao integrar abordagens psiquiátricas no cuidado multidisciplinar, é possível oferecer uma avaliação abrangente das questões emocionais, comportamentais e cognitivas associadas ao TEA. Dessa forma, essa abordagem colaborativa promove a individualização do cuidado, reconhecendo a diversidade de manifestações do TEA e adaptando as estratégias terapêuticas de acordo com as características únicas de cada paciente.
PENGARUH BUDAYA ORGANISASI DAN KEPUASAAN KERJA TERHADAP PRESTASI KERJA KARYAWAN PT. SAMPOERNA KAYOE
Authors: Rahmi Rahmi , Kusdarianto Indra , Samsinar Samsinar 
Published: January 2024

Penelitian ini untuk melihat dan menganalisis Pengaruh Budaya Organisasi Dan Kepuasaan kerja Organisasi Terhadap Prestasi kerja karyawan. Dimana sampel yang dijadikan responden yaitu sebanyak 100 pegawai. Teknik pengumpulan data yang digunakan yaitu dengan membagikan kuesioner kepada respoden. Metode penelitian yang di gunakan adalah regresi linier berganda. Dimana hasil penelitiannya budaya organisasi berpengaruh positif signifikan terhadap prestasi kerja karyawan. Hal tersebut ditunjukkan pada uji t bahwa nilai prob. reward lebih kecil dari taraf alpha 5%. Dengan demikian menunjukkan bahwa budaya organisasi yang di terima oleh karyawan sangat berpengaruh pada prestasi kerja karyawan. Dimana hasil penelitiannya kepuasaan kerja berpengaruh positif signifikan terhadap prestasi kerja karyawan. Hal tersebut ditunjukkan pada uji t bahwa nilai prob. reward lebih kecil dari taraf alpha 5%. Dengan demikian menunjukkan bahwa kepuasaan kerja yang di terima oleh karyawan sangat berpengaruh pada prestasi kerja karyawan
PENGARUH CELEBRITY ENDORSER, BRAND IMAGE DAN KUALITAS PRODUK TERHADAP KEPUTUSAN PEMBELIAN SKINCARE MS GLOW DI REMBANG KOTA
Authors: Maro'ah Aliyatul , Rosyidi Syaiko 
Published: January 2024

Globalisasi modern telah mempercepat perkembangan perusahaan dan membawa perubahan terus-menerus, sehingga meningkatkan daya saing disektor bisnis. Dunia usaha perlu mempunyai rencana untuk menghadapi persaingan yang ketat dan masuknya pesaing baru. Sehingga, diperlukan penelitian tambahan untuk mendalami perilaku konsumen dan faktor-faktor yang memengaruhi dalam memutuskan pembelian mereka. Sasaran dari riset ini yaitu tentang menggambarkan dampak brand image, kualitas dari sebuah produk, dan dukungan selebriti terhadap pemilihan dalam memutuskan membeli pada sebuah produk perawatan kulit MS Glow di Kota Rembang. Responden dalam penelitian ini merujuk kepada individu yang telah menggunakan dan melakukan pembelian produk perawatan kulit MS Glow di Kota Rembang. Dengan menggunakan pendekatan pengambilan sampel accidental sampling, strategi pengambilan sampel non-probability sampling dipergunakan untuk pembuatan sampel. Jumlah sampel yang dipergunakan pada penelitian ini yaitu sejumlah 100 responden. Kemudian metode analisis yang dipergunakan adalah analisis regresi linier berganda. Berdasarkan temuan penelitian ini, disimpulkan variabel celebrity endorser, brand image dan kualitas produk memiliki efek positif signifikan serta penting konsumen dalam memutuskan membeli produk skincare MS Glow di Kota Rembang. Nilai Adjusted R Square yang ditemukan sebesar 0,434 mencerminkan 43,4% variasi dari variabel terikat/dependen, yaitu keputusan pembelian. kemudian faktor-faktor independen atau variabl bebas seperti celebrity endorser, brand image, dan kualitas produk memberikan kontribusi dengan besar 43,4%, sedangkan dai variabel lain yang tidak dibahas dalam penelitian ini memberi kontribusi sebesar 56,6%.