bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of different catheter pathways on wounds after minimally invasive radical prostatectomy: A meta‐analysis
Authors: Wang Tao , Ji Shiben , Zhang Ci , Xiang Yang , Yin Guohong 
Published: October 2023

AbstractProstate cancer is one of the most common malignancies worldwide and the fifth leading cause of cancer deaths in men. With the rapidly increasing surgical rate of minimally invasive radical prostatectomy, there is still controversy about how to use a urinary catheter post‐operatively. Thus, we attempted to compare the post‐operative wound‐related outcomes through a meta‐analysis of urethral catheterisation (UC) versus suprapubic catheterisation (SPC) after minimally invasive radical prostatectomy. As of August 2023, the authors conducted systematic searches in databases such as PubMed, Embase, Web of Science and the Cochrane Library. The authors reviewed the relevant literature separately to determine comparisons between SPC and UC treatment after radical prostatectomy. A total of 395 subjects were enrolled in the five trials, met the eligibility criteria and were included in the meta‐analysis. Data collection and analysis revealed significant differences in catheter bother to patients for surgical trauma (MD, 0.98; 95% CI, 0.48, 1.48 p = 0.0001), with SPC causing less catheter bother to patients post‐operatively; post‐operative catheter‐related problems (OR, 3.3; 95% CI, 0.03, 326.1 p = 0.61), the POD1 of the post‐operative period (MD, − 0.09; 95% CI, −0.75, 0.94 p = 0.83) and the POD3 of the post‐operative period (MD, −0.49; 95% CI, −0.99, 0.01 p = 0.06); there was no statistically significant difference in wound pain. Compared with UC, SPC patients had less post‐operative catheter distress. Thus, SPC is more beneficial in reducing post‐operative wound discomfort in patients. The validity of the results remains to be tested in more and better studies.
Two Cases of Linear Focal Elastosis (Elastotic Striae)
Authors: Chang Sung Eun , Park Il Jung , Moon Kee Chan , Koh Jai Kyoung 
Published: October 2023

AbstractLinear focal elastosis (LFE) or elastotic striae was first described by Burket in 1989 in three elderly men. They presented with striae‐like yellow palpable bands on their backs. Burket described many fine wavy bundles of elastic fibers separating the collagen in the middle to reticular dermis under microscopic examination. Until recently, there have been about 14 reported cases of LFE; elderly males are predominant. We encountered two Korean teen‐aged males with linear, reddish, palpable bands and some atrophic bands across their backs. Histopathological examination revealed that elastosis was not as prominent as in previously reported cases. Our cases might represent early‐evolving LFE.
Production and properties of a raw‐starch‐degrading amylase from the thermophilic and alkaliphilic Bacillus sp. TS‐23
Authors: Lin Long‐Liu , Chyau Charng‐Cherng , Hsu Wen‐Hwei 
Published: October 2023

The optimum temperature and initial medium pH for amylase production by Bacillus sp. TS‐23 were 55 °C and 8.5 respectively. Maximum amylase activity was obtained in a medium containing peptone and soluble starch as nitrogen and carbon sources. Activity staining revealed that two amylases with molecular masses of 150 and 42 kDa were produced when maltose, soluble starch or amylose was used as carbon source for growth, whereas only the 150 kDa protein was detected in the medium containing water‐ insoluble carbon sources. A raw‐starch‐degrading amylase was purified from culture supernatant of Bacillus sp. TS‐23. The molecular mass of the purified amylase was estimated at 42 kDa by electrophoresis. The enzyme had a pI of 4.2. The optimal pH and temperature for activity were 9.0 and 70 °C respectively. The thermoactivity of the purified enzyme was enhanced in the presence of 5 mM Ca2+; under this condition, enzyme activity could be measured at a temperature of 90 °C. The enzyme was strongly inhibited by Hg2+, Pb2+, Zn2+, Cu2+ and EDTA, but less affected by Ni2+ and Cd2+. The enzyme preferentially hydrolysed high‐molecular‐mass substrates with an α‐1,4‐glucosidic bond except glycogen. The raw starches were partly degraded by the purified amylase to yield predominantly oligosaccharides with degrees of polymerization 3, 4 and 5.
SERIAL ISSUE EVIDENCE FOR THE RELATION BETWEEN THE RISK STRUCTURE AND MATURITY: A DECOMPOSITION METHODOLOGY
Authors: Robinson R. M. , Robinson M. A. 
Published: October 2023

AbstractThe risk structure of the interest rates literature shows that coupon effects can cause changes in yield spreads as maturity lengthens. These effects make it difficult to empirically isolate the default risk component of the spread for coupon‐paying bonds. Attempts to calculate zero‐coupon risk structures suffer from the relative scarcity of zero‐coupon corporate bonds. We show that yield spreads for coupon‐paying bonds that are identical except for default risk decompose into a relative duration component, a premium discount coupon component, and a default component. We present closed‐form solutions for measuring the first two components so that the default risk portions can be isolated as residuals. We further present an empirical application of the decomposition metrics for sixteen exchange‐traded serial issues and nonparametrically examine the relation between the default premia and maturity. We find various maturity relations.
CHANGES IN THE STOCK PRICE REACTION OF SMALL FIRMS TO COMMON INFORMATION
Authors: Fargher Neil L. , Weigand Robert A. 
Published: October 2023

AbstractWe hypothesize that changes in the technological and regulatory environment result in a more rapid response to marketwide information by small firms. We find that the correlations between small‐firm returns and lagged large‐firm returns decline over time, which suggests an increase in the efficiency of capital markets. Similar lead‐lag patterns are found in the returns of portfolios sorted by dollar trading volume. The price response of low‐volume stocks improves over time in much the same way as that of small‐capitalization stocks.
THE EFFECT OF THE SEC'S ORDER‐HANDLING RULES ON NASDAQ
Authors: McInish Thomas H. , Van Ness Bonnie F. , Van Ness Robert A. 
Published: October 2023

AbstractWe study the effect of the implementation of new Securities and Exchange Commission order‐handling rules—the Limit Order Display Rule, the Quote Rule, and the Actual Size Rule—on NASDAQ's quoting and trading behavior. We find that the number of reported quotes increases and the bid‐ask spread decreases following the implementation of the new rules. The decreased quoted depth associated with placement of individual investors' limit orders—the Limit Order Display Rule—outweighs the increased quoted depth associated with displaying institutional quotes—the Quote Rule. Further, the number of trade executions increases while the average trade size decreases. The volatility of trade‐to‐trade and midpoint returns decreases for the initial group of stocks subject to the rules, but not for the two subsequent groups.
A COMPARISON OF INDEXING AND BETA AMONG PENSION AND NONPENSION ASSETS
Authors: Horan Stephen M. 
Published: October 2023

AbstractIn this article I contrast the investment behavior of institutional portfolios having pension assets with portfolios having nonpension assets. Differences in incentive compensation plans and regulation give pension executives unique incentives to track benchmark indices. Accordingly, pension assets are more likely than nonpension assets to be allocated to index funds. Also, portfolios composed of pension assets are more likely than other portfolios to (i) have low tracking error in absolute value, (ii) be index funds, and (iii) have market betas close to one. Portfolios with relatively large pension asset market share exhibit similar characteristics and the tendency to index increases with asset class risk. Actively managed pension assets are also more likely to be invested in lower risk asset classes than actively managed nonpension assets.
The impact of visiting restrictions in intensive care units for families during the COVID‐19 pandemic: An integrative review
Authors: Mailer Jackie , Ward Kim , Aspinall Cathleen 
Published: October 2023

AbstractAimTo synthesize current evidence about the impact visiting restrictions in adult intensive care units have on family members during the COVID‐19 pandemic.DesignIntegrative literature review.MethodsA total of 104 articles were retrieved. Screening yielded a total of 23 articles which were appraised for quality. Reflexive thematic analysis was applied to synthesize findings and extract themes.Data SourcesCINAHL Plus, Ovid MEDLINE, PubMed and ProQuest databases were searched for articles between January 2020 and November 2022.ResultsThe findings were grouped into two main themes with six subthemes. Theme 1: not being present at the bedside, and Theme 2: altered communication added to family members' distress. Findings indicate that visiting restrictions imposed during the COVID‐19 pandemic had negative consequences for family members.ConclusionThe patient and their family are inherently connected, prioritizing family presence with the return of flexible, open visitation policies in ICU must be a priority to mitigate further harm and adverse outcomes for all.Reporting MethodThe review complies with the PRISMA guidelines for reporting systematic reviews.Implications for ProfessionNursing leaders must be included in the development of future pandemic policies that advocate family‐centred care.No Patient or Public ContributionNo patient or public contribution was included in this review.
Clinical outcomes and predictors of delayed echocardiographic response to cardiac resynchronization therapy
Authors: Tsurumi Naoki , Inden Yasuya , Yanagisawa Satoshi , Hiramatsu Kei , Yamauchi Ryota , Watanabe Ryo , Suzuki Noriyuki , Shimojo Masafumi , Suga Kazumasa , Tsuji Yukiomi , Murohara Toyoaki 
Published: October 2023

AbstractIntroductionThe clinical outcomes and mechanisms of delayed responses to cardiac resynchronization therapy (CRT) remain unclear. We aimed to investigate the differences in outcomes and gain insight into the mechanisms of early and delayed responses to CRT.MethodsThis retrospective study included 110 patients who underwent CRT implantation. Positive response to CRT was defined as ≥15% reduction of left ventricular (LV) end‐systolic volume on echocardiography at 1 year (early phase) and 3 years (delayed phase) after implantation. The latest mechanical activation site (LMAS) of the LV was identified using two‐dimensional speckle‐tracking radial strain analysis.ResultsSeventy‐eight (71%) patients exhibited an early response 1 year after CRT implantation. Of 32 non‐responders in the early phase, 12 (38%) demonstrated a delayed response, and 20 (62%) were classified as non‐responders after 3 years. During the follow‐up time of 10.3 ± 0.5 years, the delayed and early responders had a similar prognosis of mortality and heart failure (HF) hospitalization. In contrast, non‐responders had a worse prognosis. Multivariate analysis revealed that a longer duration (months) between initial HF hospitalization and CRT (odds ratio [OR]: 1.126; 95% confidence interval [CI]: 1.036–1.222; p = .005), non‐exact concordance of LV lead location with LMAS (OR: 32.744; 95% CI: 1.101–973.518; p = .044), and pre‐QRS duration (OR: 0.901; 95% CI: 0.827–0.981; p = .016) were independent predictors of delayed response to CRT compared with early response.ConclusionThe prognoses were similar regardless of the response time after CRT. A longer history of HF, suboptimal LV lead position, and shorter pre‐QRS duration were related to delayed response than early response.
Geographical distribution and molecular characterization of tomato leaf curl and its vector across the Himalayan foothills in Uttarakhand, India
Authors: Rakhonde Gaurav , Singh K. P. , Aravind T. , Surbhi Kumari , Jeena Himani , Bhatt Pooja 
Published: October 2023

AbstractTomato leaf curl disease is a serious constraint to tomato cultivation across the globe. The disease is characterized by leaf curling, crinkling, stunting and puckering with the drastic reduction in plant growth and yield. During two‐year survey in major tomato‐growing belt of Tarai region located in foothills of Himalayas in Uttarakhand, India, the mean incidence and per cent disease index of the disease were found to be 68.76% and 67.19%, respectively. In the morphological analysis using electron microscopy, pathogen contains twin geminate particles measuring 30 × 20 nm. The PCR amplification using RUGEMF1 and RUGEMR1 primers and sequencing of the amplicons, revealed more than 97% similarity to Tomato leaf curl New Delhi Virus (ToLCNDV). Thus, based on the sequence similarity, morphology and whitefly transmission, begomovirus isolate was recognized as a Tomato leaf curl New Delhi virus and designated as ToLCNDV_[Pant]. Amplification and sequencing of the Bemisia tabaci partial mtCOI gene from the Tarai region revealed the prevalence of Asia‐II‐1 cryptic species in the region. The overall mean pairwise distance across the 10 sequences studied was 0.0139, whereas the reference Asia‐II‐1 distance ranged from 0.0031 to 0.0332. The current investigation will aid in the development of an integrated strategy to ToLCD management.
Resveratrol modulates the inflammatory response in hPDLSCs via the NRF2/HO‐1 and NF‐κB pathways and promotes osteogenic differentiation
Authors: Ma Yifan , Qian Yi , Chen Yuteng , Ruan Xiaoxu , Peng Xiaoya , Sun Yi , Zhang Jue , Luo Jingjing , Zhou Songlin , Deng Chao 
Published: October 2023

AbstractObjectiveThe purpose of this study was to investigate resveratrol's specific role as an anti‐inflammatory and osteogenic differentiation of hPDLSCs in periodontitis and to reveal the mechanisms involved.BackgroundNumerous studies have shown that inhibiting the inflammatory response of periodontal tissues and promoting the regeneration of alveolar bone are crucial treatments for periodontitis. Resveratrol has been found to have certain anti‐inflammatory property. However, the anti‐inflammatory mechanism and osteogenic effect of resveratrol in periodontitis are poorly understood.Materials and MethodsWe constructed an in vitro periodontitis model by LPS stimulation of hPDLSCs and performed WB, RT‐qPCR, and immunofluorescence to analyze inflammatory factors and related pathways. In addition, we explored the osteogenic ability of resveratrol in in vitro models.ResultsIn vitro, resveratrol ameliorated the inflammatory response associated with activation of the NF‐κB pathway through activation of the NRF2/HO‐1 pathway, characterized by inhibition of p65/p50 nuclear translocation and the proinflammatory cytokines interleukin‐1β levels. Resveratrol also has a positive effect on osteogenic differentiation.ConclusionsObservations suggest that resveratrol modulates the inflammatory response in hPDLSCs via the NRF2/HO‐1 and NF‐κB pathways and promotes osteogenic differentiation.
Complex dynamics of coral gene expression responses to low pH across species
Authors: Radice Veronica Z. , Martinez Ana , Paytan Adina , Potts Donald C. , Barshis Daniel J. 
Published: October 2023

AbstractCoral capacity to tolerate low pH affects coral community composition and, ultimately, reef ecosystem function. Low pH submarine discharges (‘Ojo’; Yucatán, México) represent a natural laboratory to study plasticity and acclimatization to low pH in relation to ocean acidification. A previous >2‐year coral transplant experiment to ambient and low pH common garden sites revealed differential survivorship across species and sites, providing a framework to compare mechanistic responses to differential pH exposures. Here, we examined gene expression responses of transplants of three species of reef‐building corals (Porites astreoides, Porites porites and Siderastrea siderea) and their algal endosymbiont communities (Symbiodiniaceae) originating from low pH (Ojo) and ambient pH native origins (Lagoon or Reef). Transplant pH environment had the greatest effect on gene expression of Porites astreoides hosts and symbionts and P. porites hosts. Host P. astreoides Ojo natives transplanted to ambient pH showed a similar gene expression profile to Lagoon natives remaining in ambient pH, providing evidence of plasticity in response to ambient pH conditions. Although origin had a larger effect on host S. siderea gene expression due to differences in symbiont genera within Reef and Lagoon/Ojo natives, subtle effects of low pH on all origins demonstrated acclimatization potential. All corals responded to low pH by differentially expressing genes related to pH regulation, ion transport, calcification, cell adhesion and stress/immune response. This study demonstrates that the magnitude of coral gene expression responses to pH varies considerably among populations, species and holobionts, which could differentially affect acclimatization to and impacts of ocean acidification.
Neurophysiological responses to emotional faces predict dynamic fluctuations in affect in adolescents
Authors: Letkiewicz Allison M. , Funkhouser Carter J. , Umemoto Akina , Trivedi Esha , Sritharan Aishwarya , Zhang Emily , Buchanan Savannah N. , Helgren Fiona , Allison Grace O. , Kayser Jürgen , Shankman Stewart A. , Auerbach Randy P. 
Published: October 2023

AbstractThe ability to accurately identify and interpret others' emotions is critical for social and emotional functioning during adolescence. Indeed, previous research has identified that laboratory‐based indices of facial emotion recognition and engagement with emotional faces predict adolescent mood states. Whether socioemotional information processing relates to real‐world affective dynamics using an ecologically sensitive approach, however, has rarely been assessed. In the present study, adolescents (N = 62; ages 13–18) completed a Facial Recognition Task, including happy, angry, and sad stimuli, while EEG data were acquired. Participants also provided ecological momentary assessment (EMA) data probing their current level of happiness, anger, and sadness for 1‐week, resulting in indices of emotion (mean‐level, inertia, instability). Analyses focused on relations between (1) accuracy for and (2) prolonged engagement with (LPP) emotional faces and EMA‐reported emotions. Greater prolonged engagement with happy faces was related to less resistance to changes in happiness (i.e., less happiness inertia), whereas greater prolonged engagement with angry faces associated with more resistance to changes in anger (i.e., greater anger inertia). Results suggest that socioemotional processes captured by laboratory measures have real‐world implications for adolescent affective states and highlight potentially actionable targets for novel treatment approaches (e.g., just‐in‐time interventions). Future studies should continue to assess relations among socioemotional informational processes and dynamic fluctuations in adolescent affective states.
Exoribonuclease RNase R protects Antarctic
Pseudomonas syringae
Lz4W from DNA damage and oxidative stress
Authors: Mittal Pragya , Sipani Rashmi , Pandiyan Apuratha , Sulthana Shaheen , Sinha Anurag K. , Hussain Ashaq , Ray Malay K. , Pavankumar Theetha L. 
Published: October 2023

ABSTRACT

RNase R is a highly processive, 3′–5′ exoribonuclease involved in RNA degradation, maturation, and processing in bacteria. In
Pseudomonas syringae
Lz4W, RNase R interacts with RNase E to form the RNA degradosome complex and is essential for growth at low temperature. RNase R is also implicated in general stress response in many bacteria. We show here that the deletion mutant of
rnr
gene (encoding RNase R) of
P. syringae
is highly sensitive to various DNA damaging agents and oxidative stress. RNase R is a multidomain protein comprised of cold shock domain, RNB, and S1 domains. We investigated the role of each domain of RNase R and its exoribonuclease activity in nucleic acid damage and oxidative stress response. Our results revealed that the RNB domain alone without its exoribonuclease activity is sufficient to protect against DNA damage and oxidative stress. We also show that the association of RNase R with the degradosome complex is not required for this function. Our study has discovered for the first time a hitherto unknown role of RNase R in protecting
P. syringae
Lz4W against DNA damage and oxidative stress.

IMPORTANCE

Bacterial exoribonucleases play a crucial role in RNA maturation, degradation, quality control, and turnover. In this study, we have uncovered a previously unknown role of 3′–5′ exoribonuclease RNase R of
Pseudomonas syringae
Lz4W in DNA damage and oxidative stress response. Here, we show that neither the exoribonuclease function of RNase R nor its association with the RNA degradosome complex is essential for this function. Interestingly, in
P. syringae
Lz4W, hydrolytic RNase R exhibits physiological roles similar to phosphorolytic 3′–5′ exoribonuclease PNPase of
E. coli
. Our data suggest that during the course of evolution, mesophilic
E. coli
and psychrotrophic
P. syringae
have apparently swapped these exoribonucleases to adapt to their respective environmental growth conditions.
Complete genome sequence of
Paramuribaculum intestinale
DSM 100749
T
, isolated from feces of C57BL/6 laboratory mice
Authors: Low Adrian , Koh Xiu Qi , Ding Yichen , Seedorf Henning 
Published: October 2023

ABSTRACT

Here, the complete genome of
Paramuribaculum intestinale
type strain DSM 100749
T
(=JCM 33114
T
) is presented.
P. intestinale
is a recently described species of
Muribaculaceae
and was isolated from the gut of C57BL/6 laboratory mice. The genome can serve as an important resource for comparative genomics approaches.
mSphere of Influence: Hooray for HaloTag! A novel tool to study autophagy in mammalian cells
Authors: Cheney Laura 
Published: October 2023

ABSTRACT

Laura Cheney works at the crossroads of HIV and autophagy, a critical biological process for cellular homeostasis, to understand more completely the pathogenesis of HIV-associated neurocognitive impairment. In this mSphere of Influence article, she reflects on how “A pulse-chasable reporter processing assay for mammalian autophagic flux with HaloTag” by Willa Wen-You Yim, Hayashi Yamamoto, and Noboru Mizushima (eLife 11:e78923, 2022,
https://doi.org/10.7554/eLife.78923
) expands the tools for studying autophagy and inspired her to use this technology to develop a reporter to study autophagy of mitochondria, termed mitophagy, to further her own research goals.