bluuebunny/crossref_metadata_2025_split huggingface dataset:
Beyond central‐tendency: If we agree discrete vegetation communities do not exist, should we investigate other methods of clustering?
Authors: Tozer Mark G. , Keith David A. 
Published: November 2023

AbstractClustering is indispensable in the quest for robust vegetation classification schemes that aim to partition, summarise and communicate patterns. However, clustering solutions are sensitive to methods and data and are therefore unstable, a feature that is usually attributed to noise. Viewed through a central‐tendency lens, noise is defined as the degree of departure from type, which is problematic since vegetation types are abstractions of continua, and so noise can only be quantified relative to the particular solution at hand. Graph theory models the structure of vegetation data based on the interconnectivity of samples. Through a graph‐theoretic lens, the causes of instability can be quantified in absolute terms via the degree of connectivity among objects. We simulated incremental increases in sampling intensity in a dataset over five iterations and assessed classification stability across successive solutions derived using algorithms implementing, respectively, models of central‐tendency and interconnectivity. We used logistic regression to model the likelihood of a sample changing groups between iterations as a function of distance to the centroid and degree of interconnectivity. Our results show that the degree to which samples are interconnected is a more powerful predictor of instability than the degree to which they deviate from their nearest centroid. The removal of weakly interconnected samples resulted in more stable classifications, although solutions with many clusters were apparently inherently less stable than those with few clusters, and improvements in stability flowing from the removal of outliers declined as the number of clusters increased. Our results reinforce the fact that clusters abstracted from continuous data are inherently unstable and that the quest for stable, fine‐scale classifications from large regional datasets is illusory. Nevertheless, our results show that using models better suited to the analysis of continuous data may yield more stable classifications of the available data.
Dual intelligent reflecting surfaces aided decode‐and‐forward relaying with wireless power transfer
Authors: Zhang Luyu , Zhai Chao , Zheng Lina , Si Wen 
Published: November 2023

AbstractWe consider an energy harvesting (EH)‐based cooperative relaying system, where the relay operates with EH and forwards source data to the destination according to the decode‐and‐forward protocol. Two intelligent reflecting surfaces (IRSs) are deployed to assist the EH of the first‐hop as well as the data transmissions of both hops. Along with the source transmitting data to the relay at the first‐hop, the first IRS reflects the incident signal to the relay, who can harvest energy and decode information from the received signal using power‐splitting or time‐switching method. After successfully decoding the source data, the relay will forward data to the destination by using the harvested energy with assistance from the second IRS. We analyze and derive the success probability, the throughput, and the ergodic capacity of the proposed scheme. Numerical results show that our proposed dual‐IRS‐aided relaying scheme can achieve much better performance than relay‐only and one‐IRS‐aided relaying schemes.
Preserving nutrient content in red cabbage juice powder via foam‐mat hybrid microwave drying: Application in fortified functional pancakes
Authors: Ozcelik Muhammed Mustafa , Aydin Sedef , Aydin Ebru , Ozkan Gulcan 
Published: November 2023

AbstractRed cabbage, a highly nutritious cool‐season cruciferous vegetable, is rich in anthocyanins; however, the instability of anthocyanins during processing and storage poses challenges. This study aimed to optimize the foam‐mat drying process of red cabbage juice (RCJ) with a high anthocyanin content using a hybrid microwave hot air‐drying system (MW‐HAD) as a dehydration method compared to conventional techniques (HAD) using response surface methodology (RSM). Additionally, the produced red cabbage juice powder (RCJP) was used to enrich the pancake formulation. The developed model exhibited a high degree of reliability with optimal conditions and was determined for microwave power, temperature, foaming agent carboxymethylcellulose (CMC), and egg white protein (EWP) as 360 W, 60°C, 0.3%, and 1.2%, respectively. Moisture content (%) was decreased from 93.47 to 8.62 at optimum process conditions. In comparison to the control (60°C), foam mat drying with the MW‐HAD hybrid system reduced the drying time (DT) by more than 90.9% due to the higher drying rate, while many physicochemical properties, especially total anthocyanin content (TAC), were better preserved. Utilization of RCJP in the production of anthocyanin‐rich functional pancakes resulted in enhanced nutritional qualities compared to control pancakes with increased protein (35.07%), total phenolic (75.8%), dietary fiber (82.9%), and anthocyanin content (100%). In conclusion, MW‐HAD demonstrates significant potential as a promising drying method to reduce the DT and preserve the physicochemical properties of RCJP. Furthermore, the application of the optimized RCJP in anthocyanin‐rich functional pancakes highlights improved nutritional qualities, making a substantial contribution to the advancement of functional foods.
Efficacy of a dietary supplement derived from five edible plants on telomere length in Thai adults: A randomized, double‐blind, placebo‐controlled trial
Authors: Praengam Kemika , Tuntipopipat Siriporn , Muangnoi Chawanphat , Jangwangkorn Chatdao , Piamkulvanich Olan 
Published: November 2023

AbstractMylife/Mylife100® is a dietary supplement consisting of black sesame seed, guava fruit, mangosteen aril, pennywort leaves, and soy protein. These edible plants contain multiple high‐potential bioactive compounds exerting various vital biological functions including antioxidants which contribute to delaying the rate of telomere shortening. Telomere length is associated with cellular aging and age‐related diseases. This study aimed to assess the efficacy of Mylife/Mylife100® on telomere length through a randomized, double‐blind placebo‐controlled trial. The trial assessed the alteration of leukocyte telomere length after 32 adults aged 50–65 years received either Mylife/Mylife100® or placebo (five capsules/day) for 8‐week supplementation. The results demonstrated a significant increase in mean telomere length from baseline (6313 bp) to the 8‐week supplementation period (6655 bp; p < 0.05) in the group receiving the product, whereas no significant change was observed in the placebo group. Additionally, the product group exhibited a significant improvement in plasma total antioxidant capacity levels compared to the placebo group (mean change, +35 vs −38; p = 0.006). This study also showed a significant correlation between telomere length and % CD4 + T cells (r = +0.325; p = 0.00003), % CD8 + T cells (r = +0.156; p = 0.048), and visceral fat (r = − 0.349; p = 0.000006). The findings suggest that consuming this dietary supplement (Mylife/Mylife100®) for 8 weeks has a positive effect on cellular aging by lengthening telomeres possible through their antioxidant capacities. Oxidative stress and cellular aging are underlying predisease mechanisms that might be alleviated by supplementing with this product.
Evaluation of common protein biomarkers involved in the pathogenesis of respiratory diseases with proteomic methods: A systematic review
Authors: Rezaeeyan Hadi , Arabfard Masoud , Rasouli Hamid R. , Shahriary Alireza , Gh B. Fatemeh Nobakht M. 
Published: November 2023

AbstractAimRespiratory disease (RD) is one of the most common diseases characterized by lung dysfunction. Many diagnostic mechanisms have been used to identify the pathogenic agents of responsible for RD. Among these, proteomics emerges as a valuable diagnostic method for pinpointing the specific proteins involved in RD pathogenesis. Therefore, in this study, for the first time, we examined the protein markers involved in the pathogenesis of chronic obstructive pulmonary disease (COPD), idiopathic pulmonary fibrosis (IPF), asthma, bronchiolitis obliterans (BO), and chemical warfare victims exposed to mustard gas, using the proteomics method as a systematic study.Materials and MethodsA systematic search was performed up to September 2023 on several databases, including PubMed, Scopus, ISI Web of Science, and Cochrane. In total, selected 4246 articles were for evaluation according to the criteria. Finally, 119 studies were selected for this systematic review.ResultsA total of 13,806 proteins were identified, 6471 in COPD, 1603 in Asthma, 5638 in IPF, three in BO, and 91 in mustard gas exposed victims. Alterations in the expression of these proteins were observed in the respective diseases. After evaluation, the results showed that 31 proteins were found to be shared among all five diseases.ConclusionAlthough these 31 proteins regulate different factors and molecular pathways in all five diseases, they ultimately lead to the regulation of inflammatory pathways. In other words, the expression of some proteins in COPD and mustard‐exposed patients increases inflammatory reactions, while in IPF, they cause lung fibrosis. Asthma, causes allergic reactions due to T‐cell differentiation toward Th2.
Identification of a 17 kDa protein that is a potentially novel antigen of lettuce‐associated respiratory allergy in farmers
Authors: Yoshioka Junya , Nagano Tatsuya , Sekiya Reina , Yano Erika , Hatano Naoya , Katsurada Naoko , Yamamoto Masatsugu , Tachihara Motoko , Uno Yuichi , Moriyama Tatsuya , Nishimura Yoshihiro , Kobayashi Kazuyuki 
Published: November 2023

AbstractBackgroundWe have identified and reported a novel antigen, nonprotein‐specific secreted EP1‐like glycoprotein (51 kDa), for lettuce‐related respiratory allergy.ObjectiveWe aimed to identify a novel antigen for lettuce‐related respiratory allergy that is different from epidermis‐specific secreted EP1‐like glycoprotein.MethodsImmunoblotting was performed using an immunoglobulin E‐specific antibody. The antigen‐antibody reaction was confirmed by means of enzyme‐linked immunosorbent assaying. LC‒MS/MS analysis was carried out to detect a novel protein found in sera from 3 of 13 patients with lettuce‐related respiratory allergy. Finally, we purified a novel protein from Escherichia coli.ResultsImmunoblotting assays showed common bands of 17 kDa in the sera of 3 of 13 patients. An enzyme‐linked immunosorbent assay confirmed that the patient sera reacted with lettuce latex juice. A 17 kDa protein band that showed antigenic reactivity in 3 of 13 patient sera was identified as a kirola‐like protein by LC‒MS/MS. In addition, although we purified this protein, we failed to show the inhibitory effect.ConclusionA 17 kDa protein that is a potentially novel antigen of lettuce‐associated respiratory allergy was identified. In further studies, we will focus on purifying this novel protein to diagnose lettuce allergy.
Vesical ectopic pregnancy due to vesicouterine fistula: A case report with literature review
Authors: Abdalla Geyessar M. , Abdelfadeel Motwalli A. , Alfaraga Mohamed A. , Elshambaty Yasir B. , Masoud Muhammad S. , Saeed Altahir A. , Ahmed Khabab A. H. M. , Abdalla Mohammed A. , Abdelmoneim Abdelrahman H. , Fadl Hiba A. O. 
Published: November 2023

AbstractThis case report describes the presentation, diagnosis, and surgical management of a rare vesical ectopic pregnancy in a 36‐year‐old woman with a history of multiple cesarean sections. The patient presented with symptoms of suprapubic pain, fever, and amenorrhea. An initial ultrasound indicated retained products of conception, leading to a preliminary diagnosis of septic miscarriage. However, subsequent rescanning revealed an empty uterus and a non‐viable fetus within the bladder, connected to the uterine cavity. Cystoscopy confirmed the presence of fetal parts inside the bladder. Finally, a laparotomy was performed and the fetus was removed from the bladder with repair of the underlying uterovesical fistula. An uneventful postoperative period ensued. The literature review revealed only four previously reported cases with similar overall presentations. This case highlights the importance of considering vesical ectopic pregnancies in patients with a history of cesarean sections and unusual symptoms, as prompt surgical intervention is crucial for ensuring successful management of the condition.
Using underutilized residues of coffee to obtain valuable dietary and antioxidant bioactive compounds
Authors: Carréra Jéfyne Campos , de Souza Ray Rodrigues , Batista Ana Claudia Gama , Campolina Gabriela Aguiar , da Silva Júnior Francides Gomes , Gavilanes Manuel Losada , Guimarães Rubens José , das Graças Cardoso Maria , Mori Fábio Akira 
Published: November 2023

AbstractBACKGROUNDCoffee cultivation and agroindustry generate residues that are rich in several metabolites. These compounds, such as phenolic compounds and alkaloids, are known for their antioxidant activity and are usually consumed as nutraceuticals. The purpose of this study was to evaluate the occurrence of chemical and antioxidant components of low‐pruned coffee stems under different fertilizer regimes. Extractives and lignin composition, histochemical, chromatographic, and antioxidant analyses were performed.RESULTSMultiple compounds were found to accumulate in the stems of coffee trees. Furthermore, the presence of phenolic compounds such as chlorogenic acid, vanillin, resveratrol, and the alkaloids caffeine and trigonelline varied depending on the type of fertilization. In all samples examined, optimal performance was observed at the highest tested concentration (500 μg mL−1). All samples analyzed presented a great performance at the highest concentration tested (500 μg mL−1), with the dose 70% and the dose 100%, which is the recommended for the culture, showing the highest values for most of the concentrations and the best half‐maximal inhibitory concentration (IC50) when compared with the other samples tested.CONCLUSIONAs shown in the results, the reuse of stem residues as antioxidant material, with the potential to be profitable, and has the added benefit of providing a sustainable destination for material that until now has been underutilized. © 2023 Society of Chemical Industry.
A duality for prescribed mean curvature graphs in Riemannian and Lorentzian Killing submersions
Authors: Del Prete Andrea , Lee Hojoo , Manzano José Miguel 
Published: November 2023

AbstractWe develop a conformal duality for space‐like graphs in Riemannian and Lorentzian three‐manifolds that admit a Riemannian submersion over a Riemannian surface whose fibers are the integral curves of a Killing vector field, which is time‐like in the Lorentzian case. The duality swaps mean curvature and bundle curvature and sends the length of the Killing vector field to its reciprocal while keeping invariant the base surface. We obtain two consequences of this result. On the one hand, we find entire graphs in Lorentz–Minkowski space with prescribed mean curvature a bounded function with bounded gradient. On the other hand, we obtain conditions for the existence and nonexistence of entire graphs which are related to a notion of the critical mean curvature.
Nonprofit good governance mechanisms: A systematic literature review
Authors: Ortega‐Rodríguez Cristina , Martín‐Montes Lucía , Licerán‐Gutiérrez Ana , Moreno‐Albarracín Antonio Luis 
Published: November 2023

AbstractThere is widespread acknowledgment of the importance of nonprofit good governance with a need for guidance on different effective mechanisms to increase ethical practices for the whole sector to assist professionals and researchers. This study explores two research questions: (1) What are the main reasons that inspire nonprofit organizations (NPOs) to implement good governance mechanisms? (2) What are the good governance mechanisms conducted by NPOs? The purpose is to serve as a reference and an instrument of reflection for interested NPOs exploring good governance mechanisms to make their accountability work more effective. We used a systematic literature review methodology for identification, selection, and analysis of published research on nonprofit good governance. A set of 89 articles published until 2021 was analyzed, and a new classification that identified 3 lines and 13 sublines of research was provided. Our results show that a variety of internal mechanisms and international third‐party initiatives are underpinned by the need to adhere to standards of ethics and honesty.
Early and late urinary continence outcomes after unilateral and bilateral nerve‐sparing robot‐assisted radical prostatectomy: A retrospective multicentre cohort study in Japan (the MSUG94 group)
Authors: Sakaguchi Kazushige , Ebara Shin , Tatenuma Tomoyuki , Sasaki Takeshi , Ikehata Yoshinori , Nakayama Akinori , Kawase Makoto , Toide Masahiro , Yoneda Tatsuaki , Teishima Jun , Makiyama Kazuhide , Inoue Takahiro , Kitamura Hiroshi , Saito Kazutaka , Koie Takuya , Koga Fumitaka , Urakami Shinji 
Published: November 2023

AbstractBackgroundThe impact of unilateral and bilateral nerve‐sparing robot‐assisted laparoscopic radical prostatectomy (NS‐RARP) procedures on continence and the time to continence recovery have not been established.Material and MethodsWe retrospectively reviewed a total of 2801 patients who underwent RARP in 9 institutions. Procedures were classified as NS or non‐NS; NS procedures were further classified as unilateral or bilateral. The recovery of continence was analysed using propensity score matching method.ResultsThe pad‐free rates at 12 months after surgery were higher in the NS group (95% confidence interval of odds ratio, 1.06–1.51). Pad‐free rates at all time points within 12 months of surgery did not significantly differ between the unilateral and bilateral NS groups.ConclusionsNS‐RARP resulted in better urinary continence outcomes than non‐NS‐RARP in the first 12 months after surgery. Urinary recovery rates did not significantly differ between unilateral and bilateral NS‐RARP.
On the exact parameter estimation of robot manipulators with a predefined minimal amount of excitation
Authors: Arteaga Marco A. 
Published: November 2023

AbstractAdaptive control of robot manipulators has been widely used in the last decades. The main control goal is usually trajectory tracking, but exact parameter estimation is always desirable. In the recent years, the so called dynamic regressor extension and mixing (DREM) procedure was developed to provide an alternative in the design of adaptive laws with more relaxed parameter convergence conditions than the Persistency of Excitation (PE). This article proposes an innovative DREM based adaptive scheme with the ability of increasing a minimal amount of excitation to the level necessary to obtain exact parameter estimation in finite time. Furthermore, a new robust control law is proposed to guarantee trajectory tracking even if exact parameter estimation does not take place. Simulation results are in good accordance with the developed theory.
Individualized Language Plans: Promises and Pitfalls
Authors: Kangas Sara E. N. , Cioè‐Peña María 
Published: November 2023

AbstractIn the United States, individualized language plans (ILPs) have gained traction across K–12 schools. Much like the Individualized Education Programs (IEPs) used in special education, ILPs outline individualized goals, accommodations, and services for multilingual learners for their language development; however, unlike IEPs, ILPs are developed at the local level with no federal oversight or guidance. While scholars have recently called for the implementation of ILPs as a mechanism for promoting systemic change, there is a scarcity of scholarship that critically discusses or examines ILPs. In response to this gap, in this Teaching Issue article, we draw upon a combination of prior research, policy guidance, and our own review of ILP templates mandated or recommended in various states across the United States, to identify the characteristics, affordances, and constraints of ILPs. After discussing the promises and pitfalls of large‐scale implementation of these tools, we close this paper with two recommendations for teachers and policymakers who may consider adopting ILPs: to emphasize instructional support and a multiplicity of data and voices.
Late gastroenterological complications in children after allogeneic hematopoietic stem cell transplantation: A retrospective cohort study and a case series of children treated with Kampo medicines
Authors: Kawashima Nozomu , Kataoka Shinsuke , Hamada Motoharu , Nishikawa Eri , Taniguchi Rieko , Narita Atsushi , Muramatsu Hideki , Nishio Nobuhiro , Takahashi Yoshiyuki 
Published: November 2023

AbstractAimThis study aimed to describe children developing late gastrointestinal (GI) complications after allogeneic hematopoietic stem cell transplantation (allo‐HSCT), focusing on Kampo medicine.MethodsAt the Nagoya University Hospital Department of Pediatrics, 179 consecutive patients underwent allo‐HSCT over five years, of whom 167 achieved engraftment and survived at least 100 days post transplant and therefore were included in the study.ResultsThirteen patients (7.8%) developed late GI symptoms. Among these, three had upper GI symptoms, three had lower GI symptoms, while seven had upper/lower GI symptoms. Total parenteral nutrition was administered in 10 (77%) patients for a median of 81 days (range: 20–303). Four (31%) had histologically proven graft‐versus‐host‐disease (GVHD), two (15%) had adverse drug reactions, and one (8%) had a viral infection. All three patients with lower GI symptoms responded to Kampo formulas' warming interior [TM1]. Two patients with upper GI symptoms had epigastric rigidity and responded to Aurantii Fructus Immaturus‐based formulas. One patient developed severe cachexia, which was successfully reversed with Kampo medicines. There were no adverse effects due to Kampo medicines.ConclusionsLate GI complications may be a burden on children after allo‐HSCT. Kampo medicines may provide a safe and promising therapy to resolve GI symptoms not otherwise specified.