bluuebunny/crossref_metadata_2025_split huggingface dataset:
Selective zygomaticus muscle activation by ball electrodes in synkinetically reinnervated patients after facial paralysis
Authors: Arnold Dirk , Thielker Jovanna , Klingner Carsten M. , Guntinas-Lichius Orlando , Volk Gerd Fabian 
Published: October 2023

IntroductionAlthough many different treatments were developed for facial palsy, only a few therapeutic options are available for facial synkinesis. Electrical stimulation of specific muscles via implants could be useful in restoring facial symmetry in synkinetic patients. A challenge in developing stimulation devices is finding the right stimulation location, type, and amplitude. This work assesses the ability to selectively stimulate the zygomaticus muscle (ZYG) in patients with oral-ocular synkinesis to elicit a visually detectable response of the ipsilateral corner of the mouth (COM), without causing a reaction of the orbicularis oculi muscle (OOM). We aimed to assess how close to the COM the stimulation should be delivered in order to be selective.MethodsA total of 10 patients (eight females, two males) were enrolled. Facial function was graded according to the Sunnybrook facial grading system. Needle EMG was used to test the activities of the muscles, during volitional and “unintended” movements, and the degree of synkinesis of the ZYG and OOM. Two ball electrodes connected to an external stimulator were placed on the paretic ZYG, as close as possible to the COM.ResultsIndependent of the waveform with which the stimulation was presented, a selective ZYG response was observed within 4.5 cm of the horizontal plane and 3 cm of the vertical plane of the COM. When the distance between the electrodes was kept to ≤2 cm, the amplitude necessary to trigger a response ranged between 3 and 6 mA when the stimulation was delivered with triangular pulses and between 2.5 and 3.5 mA for rectangular pulses. The required amplitude did not seem to be dependent on the applied phase duration (PD), as long as the PD was ≥5 ms.ConclusionOur results show that selective stimulation of the ZYG presenting synkinetic ZYG–OOM reinnervation can be achieved using a broad PD range (25–1,000 ms) and an average amplitude ≤6 mA, which may be further decreased to 3.5 mA if the stimulation is delivered via rectangular rather than triangular waves. The most comfortable and effective results were observed with PDs between 50 and 250 ms, suggesting that this range should be selected in future studies.Clinical Trial Registration[https://drks.de/search/de/trial/DRKS00019992], identifier (DRKS00019992).
Students’ Perception on Character Education in the Novel Calabai
Authors: Nahdhiyah Nahdhiyah , Junaid Syahruni , Muzzammil Ahmad 
Published: October 2023

This study aims to find the value of character education in Novel ‘Calabai’ through students’ perception. This study also accustoms Literature students doing analysis and finding the surface and the latent meaning in a literary work. This study reveals that literary work not only displays a beautiful word string but beyond it there are meanings of life education. This study uses descriptive qualitative method where this study described the results of students’ perception about character education in novel “Calabai”. Data resource of this research is the novel Calabai by Pepy Al Bayquni. Coding sheet is used to code or to take a note of four students’ overview, understanding, thinking or interpretation on values of character education in novel Calabai. Three stages of analyzing data: deconstruction, interpretation, and reconstruction. There are 91 data contains character education. The 91 data are spreaded into 32 values of character education.
The Analysis of Politeness Strategies and Kinship Relationship: A Study Case of Wawonii Educational Background Compared to American
Authors: Ashariah Sarwin Rizki , Hakim Yassi Abdul , Sukmawaty Sukmawaty 
Published: October 2023

This research aims (1) to analyze the types of politeness strategies used by Wawonii speakers compared to American in daily conversations, and (2) to explore the educational background defined politeness strategies of Wawoniiese compared to American. The research used the quantitative research method. Wawoniiese data were collected from 32 respondents in North East Wawonii through questionnaire, observation, interview, and recorded dialogue form of speech. American data were taken from transcribed conversations of selected movies. The research result found that Wawoniiese and American speakers used four of the Politeness Strategies by Brown and Levinson. They were Bald-on-record, Positive Politeness, Negative Politeness, and Off-record. Furthermore, this research also found that the politeness systems of young and older people are almost similar, for instance, both systems showed 93,75% of speakers used deferent speech variety when talking to Parents-in-law. Meanwhile, when adding the educational background, the result showed more variations in politeness systems. Despite having age differences the older and younger family members can have conversations in mixed and casual varieties due to the influence of the educational background of speakers. For instance, the politeness systems by well-educated showed 37,5% of speakers used mixed speech variety and 56,25% of speakers used casual speech variety when talking to older cousins. Therefore, in Wawonii notably in North East Wawonii the educational background of speakers is the factor that significantly defines the choice of people's utterances compared to the variable of age. Hence, this research concluded that educational background influenced the politeness strategies of Wawonii speakers but not of American.
The EFL Students’ Perception of the Online Learning during Covid-19 Pandemic and New Normal Era
Authors: Maming Khadijah , Rizky Pratiwi Widya , Wira Rahman Ali , Bustamin Khaldun Muh. 
Published: October 2023

This research aimed to investigate the EFL students’ perception and expectation of the online learning of the online learning during Covid-19 pandemic and new normal era. This research applied quantitative and qualitative descriptive with survey method. The participants were the English education study program students consisting of fifteen participants at Universitas Muhammadiyah Parepare. In this research, the researchers conducted interview and questionnaire to obtain the data. The result of this research showed that online method was the best solution to be applied change the offline class based on the condition nowadays, but still ineffective in the application. Another result showed that in the implementation of online learning during this pandemic era there was some obstacles found and need more improvement to make learning process more effective. In brief, online learning is relatively good with several obstacles that require improvement. Thus, it is recommended to create a good learning platform that can be applicable in current situation. So that, it is recommended that online learning should be planned, implemented, and evaluated to minimize problems and maximize the achievement of learning objectives.
Perfil epidemiológico das internações hospitalares por Bronquite e DPOC no SUS em Alagoas entre 2018 a 2022
Authors: Mata Lucas Emanuel Lemos Fontes Silva , Cavalcanti Filho Rommel Oliveira , Pol-Fachin Laércio 
Published: October 2023

A Bronquite e a Doença Pulmonar Obstrutiva Crônica constituem uma importante causa de internações hospitalares pelo acometimento das vias respiratórias. No Brasil, conforme mostram os dados da Secretaria de Vigilância em Saúde através da metodologia Global Burden of Disease - Brasil, a Doença Pulmonar Obstrutiva Crônica ocupa a quinta posição dentre as causas de morte entre todas as faixas etárias, depois de doenças isquêmicas do coração, doenças cerebrovasculares, infecção de vias aéreas inferiores e Alzheimer. O objetivo deste estudo é delinear o perfil epidemiológico das internações hospitalares por bronquite e Doença Pulmonar Obstrutiva Crônica no estado de Alagoas, durante o período de janeiro de 2018 a dezembro de 2022. Métodos: Trata-se de um estudo de análise de perfil epidemiológico com caráter observacional e retrospectivo com base em dados colhidos no Sistema Único de Saúde, para o estado de Alagoas. A maioria dos casos foram registrados em pacientes de 70 a 79 anos de idade, seguidos de paciente com 80 anos ou mais, principalmente, indivíduos do sexo feminino. Conclusão: É indubitável os benefícios do Sistema Único de Saúde no controle de agravos e notificações de doenças crônicas no país, ademais, é importante ressaltar a importante repercussão negativa da pandemia pelo SARS-CoV-2 no registro de infecções hospitalares por outras síndromes respiratórias como a Bronquite e a Doença Pulmonar Obstrutiva Crônica nesse mesmo período. Por fim, é perceptível a necessidade de estratégias de saúde que auxiliem a notificação correta das internações hospitalares e que possam garantir uma análise segura do perfil epidemiológico das doenças respiratórias no estado de Alagoas.
Desafios do diagnóstico e tratamento da depressão na infância: uma revisão sistemática
Authors: Andrade Theresa Kerolayne Sousa , Sousa Carlos Eduardo da Silva , De Oliveira Arthur Campos , Portela Valnice Machado , De Carvalho Bruno Mileno Magalhães , Cavalcante Adriana Valéria Gomes , Soares Rakell Almeida , Oliveira Andressa Fernanda dos Santos Melo 
Published: October 2023

O transtorno depressivo maior é considerado um problema mundial de saúde pública e um mal típico do mundo moderno, que tem aumentado como uma epidemia em todo o mundo. Causa grave incapacitação funcional a níveis fisiológicos, afetivos e cognitivos, podendo evoluir para tendências suicidas, com inúmeros casos de suicídio efetivamente cometidos por indivíduos nesse estado. A depressão é um transtorno que pode vir a acometer a infância e, quando não bem avaliada, tende a persistir na fase da adolescência. O transtorno depressivo na faixa etária estudada é uma condição clínica grave e ocasiona prejuízos na relação do jovem com a escola, família e sociedade. O presente estudo tem como objetivo avaliar as implicações do transtorno depressivo na infância. Trata-se de uma revisão integrativa, com uso dos descritores DeCs (Descritores em Saúde) e o Medical Subject Headings (MeSH), nos idiomas português e inglês, com os seguintes termos: “Depressão” (depression), “terapêutica” (therapy), “infância” (infancy). Desta busca, foram encontrados 169 artigos, posteriormente submetidos aos critérios de seleção. A seleção resultou em 15 artigos que foram submetidos à análise seletiva, exploratória e interpretativa no contexto do presente estudo. A partir da revisão bibliográfica dos estudos analisados, conclui-se que os achados alertam para a necessidade de olhar com atenção e o mais cedo possível para a exposição de experiências adversas na infância de forma a cuidar, intervir e mitigar os efeitos negativos no momento atual, no curso de vida e em gerações futuras.
A importância do diagnóstico precoce do Retinoblastoma: uma análise sistemática
Authors: Kuwada Laura Mayumi Gramiscelli , Martins Lavínia de Fátima Baldim , Silva Beatriz Braga , Rocha Victor Reis , Fernandes Camila de Aguiar Lima 
Published: October 2023

Retinoblastoma é a malignidade ocular mais comum em crianças, sendo curável, mas com taxa de sobrevida global inferior a 30%. É associado a mutações somáticas e germinativas e representa cerca de 2,5 a 4% das neoplasias pediátricas, com 8 mil novos casos diagnosticados anualmente em todo o mundo. Estudo observacional e retrospectivo, com busca nos principais bases de dados A idade média de diagnóstico é entre 18 e 20 meses, mas em países subdesenvolvidos, a baixa conscientização pública e acesso limitado à saúde, com diagnóstico mais tardio, resultam em menor taxa de sobrevida. Em países desenvolvidos, a sobrevida para crianças com diagnóstico é superior a 95%. No Brasil, o rastreamento é feito por meio de testes de reflexo vermelho e wide-field digital retinal imaging (WFDRI), mas a sensibilidade e especificidade desses métodos variam. A conscientização pública e programas eficazes de triagem são essenciais para aumentar a detecção precoce e melhorar o prognóstico da doença. O sucesso no tratamento depende do acesso adequado à terapia, que pode levar à recuperação da visão e à taxa de sobrevida de mais de 90% em 5 anos.
Incidência de Tripanossomíase em bovinos na região Leste do Careiro da Várzea Manaus-AM
Authors: Do Vale Tarcio Mendes , Da Silva Vitor Hugo Rodrigues , Campos Livia Batista , Danin Amanda Paula Ferreira , Da Silva Mateus de Andrade 
Published: October 2023

O presente trabalho tem como objetivo realizar o levantamento da incidência de casos de tripanossomose na região do leste do careiro da várzea pertencente a cidade de Manaus-AM. Para tanto, foram utilizadas duas propriedades rurais no estado do Amazonas, especificamente na região de Careiro da Várzea, que se localiza na BR-319 próxima aos eixos rodoviários Manaus-Itacoatiara (AM-010) e Manaus-Manacapuru (AM-070). Na primeira propriedade havia 112 vacas mestiças de Girolando com Gir Leiteiro enquanto na segunda propriedade existiam 76 animais das raças Nelore e Senepol. Assim foram utilizados 25 animais aleatórios em cada fazenda para a coleta de sangue totalizando 50 amostras. Nos exames de esfregaços sanguíneos realizados nos 25 animais da primeira fazenda não foi possível identificar a presença do protozoário, porém, na segunda fazenda foi encontrada duas amostras positivas para o Tripanossoma vivax, que foram identificados através do esfregaço sanguíneo de sangue periférico coletado da ponta de orelha. Conclui-se os animais provenientes da região Norte do Brasil, com ênfase para a região do Careiro do Várzea teve uma baixa incidência da ocorrência do Trypanosoma vivax.
Paciente com fístula arteriovenosa com corrente sanguínea infectada por fungo
Authors: Araújo Gabriela Lopes , Valenzuela Rolando Guillermo Vermehren 
Published: October 2023

A incidência de infecções na corrente sanguínea causadas por espécies de Candida aumentou nas últimas décadas. A Candida albicans é a principal causa da infecções; no entanto, espécies como C. parapsilosis (C. orthopsilosis e C. metapsilosis) e C. tropicalis, são identificadas como patógenos humanos. Relatar o caso de paciente com fístula arteriovenosa com corrente sanguínea infectada por fungo. Paciente, sexo feminino, 56 anos, em terapia renal substitutiva há 18 meses, com fístula arteriovenosa confeccionada em novembro de 2022. Em janeiro de 2023, a paciente apresentou calafrios durante diálise, sem foco identificado. A hemocultura isolou a Candida orthopsilosis (C. orthopsilosis) sensível ao fluconazol. Em março de 2023, com retorno dos sintomas, nova hemocultura constatou C. orthopsilosis resistente ao fluconazol. Em maio de 2023, devido aos calafrios esporádicos, novo exame mostrou persistência da C. orthopsilosis resistente ao fluconazol. E em agosto de 2023 foi identificada C. tropicalis sensível ao fluconazol e foi proposto tratamento com caspofungina devido ao padrão de resistência anteriormente apresentado. A paciente relatada apresentou as C. orthopsilosis (da espécie C. parapsilosis) e C. tropicalis. Embora menos prevalente que a C. parapsilosis, a C. orthopsilosis é frequentemente encontrada na infecção da corrente sanguínea e o fluconazol é utilizado. Já a C. tropicalis é menos sensível ao fluconazol. A paciente foi tratada com caspofungina.
Advokasi Media Sosial Yayasan Jurnal Perempuan: Upaya Penyebaran Wacana Feminisme di Era Digital
Authors: Salsabila Nada , Diera Giovanni Alvita 
Published: October 2023

Tulisan ini memaparkan kerja-kerja media sosial Yayasan Jurnal Perempuan (YJP) sebagai bentuk advokasi isu-isu feminis di ruang digital. Advokasi digital bertujuan sebagai penyeimbang narasi atau wacana di ruang digital yang kini disesaki oleh para anti-feminis, misoginis, dan seksis. Sejak 2013, YJP telah melakukan langkah untuk mendigitalisasi produk-produknya. Digitalisasi tersebut meluas pada platform media sosial YJP, seperti YouTube, Instagram, Facebook, dan Twitter. Strategi tersebut diharapkan dapat memperluas jangkauan penyebaran wacana feminis yang dilakukan YJP juga merebut ruang-ruang digital dari nilai-nilai patriarki. Tulisan ini menggunakan metode riset kualitatif dengan melakukan studi literatur dan wawancara terhadap audien YJP di media sosial. Tujuan riset ini adalah menganalisis bagaimana upaya YJP beradaptasi di ruang digital, apa saja hambatan internal dan eksternal yang dihadapi YJP, apa saja bentuk-bentuk penyebaran yang jangkauannya paling luas, hingga analisis terhadap dampak advokasi media sosial YJP terhadap penyebaran wacana feminis di ruang digital.
Improving the efficiency of water recycling systems at oil refineries and petrochemical enterprises (part 2)
Authors: Вурдова Н.Г. , Фесенко Л.Н. 
Published: October 2023

Проведены комплексные исследования с целью повышения эффективности работы сооружений водоподготовки и водоочистки одного из нефтеперерабатывающих заводов Южного федерального округа за счет добавления одной или нескольких стадий доочистки, усовершенствования конструкции действующих установок, изменения технологического процесса одной из стадий очистки на более эффективный. Задачи исследований: 1) анализ работы систем (блоков) оборотного водоснабжения, водоотведения и существующих канализационных очистных сооружений; 2) разработка оптимальных решений и схем модернизации блоков оборотного водоснабжения предприятия; 3) проработка технических мероприятий, направленных на повышение эффективности системы оборота воды, сокращение объемов сбрасываемых сточных вод завода и уменьшение объемов забора сырой воды за счет организации подпитки очищенными стоками современных блоков оборотного водоснабжения. В предыдущей статье на данную тему были приведены материалы исследований по первым двум задачам.
Comprehensive studies were carried out to improve the efficiency of water and wastewater treatment facilities at one of the oil refineries in the Southern Federal District by adding one or more stages of tertiary treatment; by improving the design of the existing facilities; and replacing the technological process of one of the treatment stages for a more efficient one. Research objectives: 1) analysis of the operation of the water recycling systems (units), existing wastewater disposal and treatment facilities; 2) development of the optimal solutions and schemes for upgrading the recycling water supply of the enterprise; 3) development of technical measures aimed at increasing the efficiency of the water recycling system, reducing the volume of wastewater discharged by the plant and reducing the amount of raw water abstraction by arranging the makeup of the existing water recycling units with effluent. The previous article on this topic presented the research materials on the first two tasks.
Optimization of designing the systems for waste water purification from waterworks operating with low-turbidity waters
Authors: Бутко Д.А. 
Published: October 2023

Рассмотрены вопросы проектирования схем обработки промывных вод скорых фильтров (контактных осветлителей), осадков сооружений обработки промывных вод и осадков отстойных сооружений. Приведены результаты исследования промывных вод скорых фильтров станций водоподготовки, работающих на органическом коагулянте-флокулянте ПолиДАДМАХ, даны качественные показатели осадка отстойников таких станций. Рассмотрены варианты утилизации промывных вод: возврат в «голову» сооружений и промывка контактных осветлителей, техническое водоснабжение (поливомоечные нужды, производственные нужды промышленных предприятий и т. п.) и полив сельскохозяйственных культур. Даны качественные показатели воды по каждому из направлений утилизации и представлен алгоритм выбора технологической схемы, позволяющий варьированием схемы обработки добиваться требуемого качества воды. Представлены варианты утилизации осадков отстойников и сооружений обработки промывных вод в почвогрунты, каменные и керамические строительные материалы. Приведены критерии выбора направления утилизации и алгоритм выбора технологических схем. Предложенный подход к проектированию схем обработки промывных вод и обработки осадка упрощает выбор их на этапе нового проектирования или реконструкции.
The issues of designing schemes for processing wash water of rapid filters (contact clarifiers), sludge from wash water treatment facilities and sludge from sedimentation facilities are considered. The results of a study of wash water of rapid filters at the water treatment plants operating with PolyDADMAC organic coagulant-flocculant are presented; the qualitative indicators of the sludge from the sedimentation tanks at these facilities are given. Options for wash water recycling are considered, such as supplying to the headworks and washing contact clarifiers, as well as process water supply (road washing, production needs of industrial enterprises, etc.), and agricultural irrigation. The water quality indicators for each of the recycling options are given, and an algorithm for selecting a process flow scheme is presented that will provide for the required effluent quality standard by adjusting the treatment scheme. Options for the utilization of sludge of sedimentation tanks and wash water treatment facilities as potting soils, stone and ceramic building materials are presented. The criteria for choosing a utilization option and the algorithm for choosing process flow schemes are presented. The proposed approach to designing schemes for wash water and sludge treatment simplifies their selection at the stage of a new design or upgrade.
Patterns of Developmental Delay in Children with Autism Spectrum Disorder: A Perspective from a Developing Country.
Authors: Raza Syed Hashim , Waris Rehamana , Riaz Ramish 
Published: October 2023

Background: Autism Spectrum Disorder is a developmental disorder characterized by difficulties in social interaction, initiating conversations, delay in language skills, play skills and stereotypic behaviours. Children with severe developmental delay and those with global developmental delays are needed to be identified as they may have long term problems and disabilities.
Materials & Methods: All children below age of 5 years coming first time for assessment of ASD and diagnosed using ADI-R and ADOS-2 were included in the study. Total 334 children met the criterion. All children having performance deficit below 2SD on age appropriate mean were considered as having developmental delay. Those having delay in two or more than two domains were labelled as having global developmental delay. Detailed clinical and developmental assessment was performed. Data was entered and analysed via SPSS v26.
Results: Mean age of children at time of presentation was 3.6±1.10 years with male to female ratio of 3.5:1. According to developmental assessment using Schedule for growing Scales II, most affected area was speech and language (51.5%) followed by cognitive skills (50.7%), social interactive skills (49.9%), visual skills (46.9%), hearing and language skills, (38.3%), self-care social skills (26.2%), manipulative skills (13.5%) and gross motor skills (0.4%). Global Developmental Delay was found to be present in half of the children for which there was no other possible explanation.
Conclusion: Most of the children with Autism Spectrum Disorder from developmental delay of some sort. Therefore, every child with Autism Spectrum Disorder must be evaluated for Developmental Delay and supported.