bluuebunny/crossref_metadata_2025_split huggingface dataset:
Glucagon-like Peptide-1 Receptor Agonist Treatment in Type 1 Diabetes
Authors: Tsoukas Michael A. 
Published: October 2023

Type 1 diabetes (T1D) is characterized by a progressive decline of insulin production due to a marked destruction of pancreatic B cells. Intensive insulin therapy is the pillar of T1D management. More recently, continuous glucose monitoring devices, closed-loop systems (CLS) and smarter connected insulin pen systems have all significantly helped individuals to improve glycemic control. Despite these advances, however, more than three-quarters of the adult T1D population does not achieve recommended glycemic targets. In addition, aggressive insulin intensification potentiates weight gain and the risk of recurrent hypoglycemic events. Recent significant increase in rates of obesity has also led to a sharp increase in T1D patients who concurrently have adiposity-based chronic disease, increasing their insulin resistance and predisposition for cardiovascular events. While insulin will remain the basis of T1D management, there is an unmet need for individualized adjunctive therapeutic approaches focusing on the prevention of diabetic complications in addition to glycemic control. One such adjunctive therapy currently being explored in T1D are the glucagon-like peptide-1 receptor agonists (GLP-1 RAs), a popular and robust approach in Type 2 diabetes (T2DM) to mimic the natural endogenous GLP-1 incretin. This brief review will focus on the rationale and existing evidence for the use of GLP-1 RAs in the management of T1D.
Nonlocal problems for hyperbolic equations from the viewpoint of strongly regular boundary conditions
Authors: Pulkina Ludmila S. 
Published: October 2023

In this article, we consider a nonlocal problem for hyperbolic equation with integral conditions and show their close connection with the notion of strongly regular boundary conditions. This has an important bearing on the method of the study of solvability. We propose also a new approach which enables us to prove a unique solvability of the nonlocal problem with integral condition.
For more information see https://ejde.math.txstate.edu/Volumes/2020/28/abstr.html
Existence of solutions for semilinear problems on exterior domains
Authors: Iaia Joseph 
Published: October 2023

In this article we prove the existence of an infinite number of radial solutions to \(\Delta u+K(r)f(u)=0\) on \(\mathbb{R}^{N}\) such that \(\lim_{r \to \infty} u(r)=0\) with prescribed number of zeros on the exterior of the ball of radius R&gt;0 where f is odd with f&lt;0 on \((0,\beta)\), f&gt;0 on \((\beta,\infty)\) with f superlinear for large \(u\), and \(K(r) \sim r^{-\alpha}\) with \( \alpha > 2(N-1)\).
For more information see https://ejde.math.txstate.edu/Volumes/2020/34/abstr.html
Mathematical methods for the randomized non-autonomous Bertalanffy model
Authors: Calatayud Julia , Caraballo Tomas , Cortes Juan Carlos , Jornet Marc 
Published: October 2023

In this article we analyze the randomized non-autonomous Bertalanffy modelwhere and are stochastic processes and is a random variable, all of them defined in an underlying complete probability space. Under certain assumptions on a, b and , we obtain a solution stochastic process, , both in the sample path and in the mean square senses. By using the random variable transformation technique and Karhunen-Loeve expansions, we construct a sequence of probability density functions that under certain conditions converge pointwise or uniformly to the density function of , . This permits approximating the expectation and the variance of . At the end, numerical experiments are carried out to put in practice our theoretical findings.
دور الحسبة في التّنمية المستدامة
Authors: د.محمد حمدكنان ميغا  
Published: October 2023

إ ّن الحسبةَ من الموضوعات التي اعتنى بها العلماء قديمًا وحديثًا، لارتباطها بحياة النّاس الدينيّة والدنيويّة، وتتمثّل في الأمر بالمعروف إذا ظهر تركه، والنّهي عن المنكر إذا أُظهر فِعلُه، – كما عّرفها الماوردي- والحسبة بهذا المفهوم، تدخل في جميع جوانب الحياة العمليّة، من أجل حماية المجتمع من سلبيّات المعاملات، والانحرافات السلوكيّة، ويظهر دور الحسبة في كونها مبدأً إسلاميًّا بها تستقيم الحياة البشرية؛ اجتماعيًّا واقتصادًّيًّ ودينيًّا، الأمر الذي به تتحّقق التنمية المستدامة في المجتمع، ويتمتّع ك ُّل فرد من أفراد المجتمع بالأمن من الخوف والجوع، وبالحسبة ينتشر الإصلاح والصلاح، وتسود المحبّة والتّناصح والتّعاون والتّناصر بين أفراد المجتمع، وبالتالي يسود العدل ويعلو الحق، ويضمح ّل الفساد والظلم في المجتمع. وهذا البحث يهدف إلى إبراز دور الحسبة في التّنمية المستدامة وذلك اعتماًدا على المنهج الوصفي والتحليلي، بتتبّع دور الحسبة عبر تاريخ الإسلام إلى يومنا هذا من مصادرها القديمة والحديثة، ترغيبًا للمجتمعات الإسلاميّة في العودة إلى إحياء نظام الحسبة بآليات حديثة تتلاءم مع حياتنا المعاصرة ولا تتعارض مع مبادئ الشريعة ومقاصدها. وقد خلص البحث إلى أ ّن الحسبة مسؤولية رقابيّة مشتركة بين الدولة وجميع أفراد المجتمع قصَد الحفاظ على مكتسبات الّدولة والمجتمع دينيًّا،
وأخلاقيًّا، واقتصادًّيًّ، وأَْمنِيًّا.
Ландшафт образования и развития педагога: от вхождения в профессию до профессиональной зрелости
Authors: Мурзалинова Алма , Мухамбетжанова Сауле , Оракова Амангул , Наметкулова Фарида 
Published: October 2023

В статье представлены результаты исследования процессов непрерывного профессионального развития в структуре профессионально-педагогического образования. Цель исследования - разработка информационно-методического сопровождения названных процессов для системы образования сложного общества, в которой востребованы самоуправление профессиональным развитием и экосистема профессионального развития. Представлены основные результаты исследования: уровневая классификация актуальных для НПР компетенций, компонентная структура данных компетенций, компетентностно-ориентированный практикум в соответствующей экосистеме. По результатам исследования сформулированы выводы о ресурсах непрерывного профессионального развития на рабочем месте педагога и в условиях взаимодействия с коллегами, инструментах устойчивого продвижения педагога в траектории развития (от становления в профессии до профессиональной идентичности и зрелости), механизмах работы в команде стейкхолдеров - от решения профессиональных затруднений педагогов и задач педагогического коллектива до руководства ценностями и смыслами развития.
Độc tính cấp và ảnh hưởng đến chức năng tạo máu của viên nang Linh quế truật cam thang - Nhị trần thang gia giảm
Authors: Tôn Mạnh Cường , Nguyễn Tuấn Bình , Trương Việt Bình , Nguyễn Hoàng Ngân 
Published: October 2023

Để đảm bảo tính an toàn của bài thuốc khi tiến hành nghiên cứu hiệu quả của chế phẩm điều trị rối loạn chuyển hóa lipid máu, chúng tôi thực hiện nghiên cứu này nhằm mục tiêu: Đánh giá độc tính cấp và ảnh hưởng lên chức năng tạo máu trên thực nghiệm của viên nang Linh quế truật cam thang - Nhị trần thang (LQTCT-NTT).
Kết quả và kết luận: Không có độc tính cấp của LQTCT-NTT khi dùng theo đường uống, với liều LQTCT- NTT cao nhất có thể đưa vào dạ dày chuột nhắt trắng là 12,0g/kg trong lượng cơ thể (gấp 25 lần liều dùng trên người) không gây chết chuột nhắt trắng thực nghiệm; LQTCT-NTT không ảnh hưởng lên chức năng tạo máu của động vật thực nghiệm ở hai liều 0,28g/kg TLCT và 0,84g/kg TLCT uống liên tục trong 90 ngày.
UPAYA MENINGKATKAN AKTIVITAS DAN HASIL BELAJAR MATERI TEKS EDITORIAL MENGGUNAKAN MODEL PEMBELAJARAN TUTORIAL TEMAN SEBAYA PADA SISWA KELAS XII IPS 1 SMA NEGERI 5 MAGELANG TAHUN PELAJARAN 2022/2023
Authors: MARDIANA YULI 
Published: October 2023

Jenis penelitian ini adalah penelitian tindakan kelas yang bertujuan meningkatkan aktivitas dan hasil belajar teks editorial pada siswa SMA Negeri 5 Magelang menggunakan model pembelajaran tutorial teman sebaya. Tempat penelitian di SMAN 5 Magelang. Peneltian ini melibatkan 36 siswa kelas XII IPS 1 yang dilakukan dalam dua siklus. Dalam setiap siklus terdiri dari tiga kali pertemuan setiap tutor membimbing secara klasikal kemudian membimbing kelompok kecil yang terdiri dari 5 anggota. Prosedur penelitian terdiri atas dua siklus. Masing-masing siklus menggunakan empat tahapan tindakan: perencanaan, pelaksanaan tindakan, observasi, dan refleksi. Berdasarkan hasil penelitian tersebut membuktikan bahwa: (1) model pembelajaran Tutorial Teman Sebaya dapat meningkatkan aktivitas belajar. Kondisi awal aktivitas siswa menduduki kategori sedang (19,67%). Setelah ada tindakan menjadi kategori tinggi (25,08%) dan pada akhir tindakan menjadi (28,29%) kategori tinggi. Persentase peningkatan aktivitas belajar siswa dari prasiklus sampai dengan siklus II sebesar (8,62%) dan (2) model pembelajaran Tutorial Teman Sebaya dapat meningkatkan hasil belajar siswa kelas XII IPS 1. Hasil belajar siswa sebelum ada tindakan (Prasiklus) pada kelas XII IPS 1 rata-rata (65) kategori cukup. Setelah menerapkan model pembelajaran tutorial teman sebaya pada Siklus I memperoleh rata-rata 73 (baik). Selanjutnya pada Siklus II skor rata-rata diperoleh angka 81 (baik). Persentase ketuntasan kelas pada Prasiklus sebesar 50%, pada Siklus I naik menjadi 58,3%, Siklus I ke Siklus II naik sebesar 11 (36,11%). Secara keseluruhan hingga akhir Siklus II terjadi peningkatan persentase ketuntasan belajar secara klasikal sebesar 16 (44,44%)..Peningkatan skor rata-rata Prasiklus ke Siklus I sebesar 8,3. Siklus I ke Siklus II naik sebesar 8. Secara keseluruhan kenaikan skor rata-rata dari Prasiklus sampai dengan Siklus II, 16 (44,44%).
An integrated residence smart grid system with enhanced energy management for batteries
Authors: Swide Sarab , Marhoon Ali 
Published: October 2023

Residential consumers can efficiently engage in demand response programs with the help of home energy management systems (HEMSs). The best scheduling of gas, oil, coal, and uranium appliances has yet to be considered by traditional HEMSs, which exclusively control domestic electric devices to lower the cost of electricity usage. The associated demand response (DR) for smart homes is then adjusted to lessen the difference between predicted and actual demand after comparing the actual price to this forecast. Data acquired by Nordpool and publicly available energy information have been used to test the proposed strategy about price demand forecast and DR management. The function is to reduce energy costs for the home and the dissatisfaction brought on by moving, cutting, and replacing loads by changing prices over time. Case studies with accurate data show that the suggested strategy can return on investment bills by up to 85% while maintaining their satisfaction.
Chromophobe: A rare histological variant of renal cell carcinoma
Authors: Adekunle AA  , Idowu NA  , Rasheed MW  , Aderibigbe OA  , Olatide OO  
Published: October 2023

Background: Renal cell carcinoma (RCC) is an adenocarcima of the kidney. It is a highly heterogeneous disease with sixteen known subtypes out of which five predominate. The most common subtype is clear cell RCC which accounts for 75-85%. The chromophobe subtype of RCC is rarely seen. It is reported to constitute 4-5% of RCC subtype. This study was aimed at reporting the first case of chromophobe renal cell carcinoma in our community a rare histological subtype of RCC which was discovered incidentally. Our objective was to describe the clinical, histological and immunohistochemical evaluation of a case of chromophobe RCC.
Case report: We present a 60-year-old man who was seen at the surgical outpatient department of our center with a request for general health check-up. He had basic laboratory and imaging investigations. These were essentially normal except for an incidental finding of a left renal mass on abdominopelvic sonogram. Computed tomography urography showed a suspected clinically localized malignant left renal mass. Histological and immunohistochemistry are consistent with a chromophobe RCC. His clinic follow-up remains unremarkable.
Conclusion: We reported the clinical, histological and immunohistochemical evaluation of a rare case of chromophobe RCC. This was discovered incidentally following general health check. He had open radical nephrectomy and clinic follow-up 1 year after discharge has been uneventful.
MENENTUKAN SETTING LEVEL OPTIMAL GUNA MENGURANGI CACAT BOTOL PADA MESIN BLOW MOLDING DENGAN METODE TAGUCHI DI PT XYZ
Authors: Nurhasan Muhammad 
Published: October 2023

Salah satu upaya perusahaan dalam meningkatkan volume penjualan suatu produk adalah dengan mempertahankan dan meningkatkan kualitas suatu produk yang telah diproduksi oleh perusahaan. Karena itu, sangat penting bagi perusahaan untuk menganalisis dan mengidentifikasi masalah yang telah ditimbulkan selama proses produksi. Masalah yang menyebabkan produk cacat dalam produksi adalah bagaimana membuat pengaturan yang optimal dari masing-masing faktor penyebab masalah yang menyebabkan produk cacat. Penelitian ini dilakukan di PT King Plastic pada produk botol Yamalube MA 800 ml. Metode Taguchi adalah salah satu metode yang dapat digunakan untuk meminimalkan produk cacat dengan menerapkan level faktor optimal. Hasil akhir adalah mengetahui faktor-faktor penyebab produk cacat yaitu Time Air Blow dengan level optimal 1 detik, Suhu Parison dengan level optimal 80°c dan Suhu Mold dengan level optimal 14°c. Loss Function pada kondisi optimal adalah Rp. 13.273.750 atau penghematan biaya sebesar 14.3%.
PERANCANGAN SISTEM KERJA DENGAN WAREHOUSE MANAGEMENT SYSTEM BERBASIS QR CODE UNTUK MENGURANGI KESALAHAN PENGIRIMAN PRODUK PLUG CAP DI PT XYZ
Authors: Gustiawan Fahmi 
Published: October 2023

. Ketidaksesuaian atau kesalahan pengiriman produk plug cap yang terjadi di PT XYZ memberikan beberapa dampak diantaranya terjadinya komplain pelanggan dan dikeluarkannya biaya tambahan oleh perusahaan untuk melakukan pengiriman ulang barang yang salah, biaya tambahan tersebut mengakibatkan kerugian bagi perusahaan.
Peneliti menggunakan metoda RCA untuk menganalisis jenis komplain yang paling sering terjadi dan faktor utama penyebab terjadinya ketidaksesuaian pengiriman produk plug cap. Selain itu, peneliti juga melakukan analisis biaya kerugian akibat dari pengiriman ulang barang.
Dari hasil penelitian didapatkan bahwa komplain pelanggan yang paling sering terjadi diakibatkan oleh miss part dengan jumlah 11 kali dari total 25 kali komplain selama periode Januari 2020 sampai September 2023, dengan total biaya tambahan pengiriman ulang sebesar Rp11.426.600. Faktor utama penyebab ketidaksesuaian pengiriman produk plug cap adalah faktor machine dan methode.
Berdasarkan hasil penelitian tersebut, maka peneliti melakukan perancangan sistem kerja dengan Warehouse Management System berbasis QR Code di bagian Warehouse finish good. Setelah dilakukan perancangan dan implementasi sistem kerja dengan Warehouse Management System berbasis QR Code di bagian Warehouse finish good, terjadi penurunan komplain yang diakibatkan oleh miss part dari 11 kali menjadi 0 komplain. Serta terjadi penurunan biaya kerugian akibat ketidaksesuaian pengiriman dari Rp11.426.600 menjadi Rp1.604.768 atau turun sebesar 85,96%.
Spatial effects of trade, foreign direct investment (FDI), and natural resource rents on carbon productivity in the GCC region
Authors: Mahmood Haider 
Published: October 2023

Background
Natural resource rents (NRRs) may determine the environment and economic growth of the GCC countries due to their over-reliance on the natural resource sector. NRRs are the source of income in resource-abundant GCC countries. So, increasing income of these countries could pollute the environment by increasing overall economic activities. Consequently, NRRs could determine carbon productivity in the GCC region through increasing income and carbon emissions.

Methods
The effects of trade openness (TO), foreign direct investment (FDI), urbanization, and oil and natural gas rents on carbon productivity (CP) are examined in the GCC region from 1980–2021 using the spatial Durbin model.

Results
The CP of the GCC countries has spillovers in their neighboring countries. Oil rent reduces carbon productivity in domestic economies and the entire GCC region. Natural gas rent, TO, and FDI increase, and urbanization reduces carbon productivity in neighboring economies and the entire GCC region. Moreover, urbanization reduces carbon productivity in domestic economies as well. The study recommends the GCC countries to reduce reliance on oil rent and increase globalization in terms of TO and FDI in the region to promote carbon productivity. Moreover, GCC countries should also focus more on natural gas rent instead of oil rent to raise carbon productivity.
Analyzing Election Sentiments in Tweets with Gated Recurrent Units (GRU)
Authors: Agu Edward O.  , Zevini Bako Jeremy , Abiola Hambali  Moshood 
Published: October 2023

Sentiment analysis, a key task in natural language processing, is important for detecting the emotional tone portrayed in text. In this study, we focus on implementing a Gated Recurrent Unit (GRU) model to analyze attitudes within the 2020 Donald Trump Election tweets dataset. By setting the GRU model with carefully selected parameters, the aim of the study is to unveil the inherent sentiment patterns in the dataset. To develop the sentiment analysis model, the study devised a three phase methodology which that include data preprocessing, feature selection using correlation matrix, and lastly the implementation of GRU. Futhermore, we provided the outcomes of our experiment, evaluating the model's performance through important measures such as accuracy, precision, and recall. Notably, our data exhibit an exceptional accuracy rate of 93%, verifying the model's power to appropriately categorize attitudes. Additionally, both recall and precision receive outstanding ratings of 94% and 96%, indicating the model's skill in distinguishing both positive and negative attitudes. This inquiry emphases the effective usage of the GRU model in sentiment analysis, shedding light on the emotional nuances within the 2020 Donald Trump dataset and enriching our understanding of sentiments during the election period.
How does Assisted Natural Regeneration (ANR) Improve Soil Fertility and Plant Cover in the Simiri Commune in Niger?
Authors: Boukary Daouda , Djabri Hassimiou Halidou , Boureima Karimou Harouna , Zoubeirou Alzouma Mayaki 
Published: October 2023

Aims: This study aimed to assess Assisted Natural Regeneration (ANR) impacts on improving soil fertility and plant cover through the physicochemical characterization of soil samples taken from ANR fields and control fields.
Study Design: The experimental design is made up of a vegetation observation gradient along an East-West transect and a soil sampling gradient along a North-South transect.
Place and Duration of Study: This study was carried out in the Sahelian zone in the rural commune of Simiri in Niger between May and June 2023.
Methodology: Data on the diversity of species predominant in the ANR system, the social categories of ANR users and farmers' perceptions of ANR were collected on a sample of 120 farmers chosen at random from three villages in the commune of Simiri.
Results: A sandy texture was recorded in all the samples submitted for analysis, with an overall acid of soil pH (5.18 ⁃ 5.62). The proportions of the main nutrients: C(0,16), N(0,015), P(6,88), K(0,066), Mo(0,30) C/N(10,83) were relatively higher in the fields under ANR practices compared with the control fields. With regard to the dominant woody species, the results show that the stands are mainly based on Combretum glutinosum, Combretum micranthum and Guera senegalensis. The ability of woody species to withstand stressful conditions could act as a bulwark against climatic hazards. The strong dominance of these species is due, among other things, to their regenerative capacity, their rapid spread and, above all, their economic interest in the production of firewood and other ecosystem services.
Conclusion: The Assisted Natural Regeneration (ANR) adoption in farming practices has often been accompanied by the creation of village committees for the protection and management of trees and other areas of sustainable natural resource management. Despite mutilation and other illegal felling, the new agroforestry parks increase the resilience of agricultural production systems to climatic shocks and biotic stresses.
Effect of Dates of Sowing on Grain Yield of Rabi Rice (Oryza sativa L.)
Authors: Reddy Boppidi Manasa , Mahadevappa S. G. , Reddy K. Indudhar , Reddy K. Pavan Chandra 
Published: October 2023

Aim: To determine the optimum date of sowing to realize higher grain yield in rabi rice.
Study Design: Split plot.
Place and Duration of Study: Krishi Vigyan Kendra, Rudrur, Nizamabad during rabi, 2022.
Methodology: The experiment consisted of a total of fifteen treatments which were laid out in split plot design with three replications. Treatments included were five dates of sowing in the main plot M1-20th November, M2-1st December, M3-10th December, M4-20th December, and M5-30th December and three treatments of varieties in subplots S1-JGL 24423 (long slender variety), S2-Ganga Kaveri (medium slender variety) and S3-RNR 15048 (short slender variety) randomly placed in subplots of the main plot.
Results: Maximum plant height (100.3 cm), number of tillers m-2 (432), dry matter accumulation (15869 kg ha-1), grain yield (7219 kg ha-1), straw yield(8387 kg ha-1) and HI (46.1) was noticed in crop Sownon 30thDecember. Significantly maximum number of tillers m-2, dry matter accumulation (14263 kg ha-1), grain yield (6127 kg ha-1), straw yield (8650 kg ha-1) was observed in S2-Ganga Kaveriwhile significantly higher plant height (100.6 cm) and HI (45.0) was found in S3-RNR 15048. Lowest height was recorded in S2-Ganga Kaveri (92.6 cm), and above parameters were recorded lowest in crop sown on 20th November, while lowest number of tillers m-2and straw yield (8122 kg ha-1) was observed in crop sown on 1st December.Significantlyless number of tillers m-2 (326), dry matter accumulation (13981 kg ha-1), grain yield (6166 kg ha-1), straw yield (7526 kg ha-1) was recorded in S3-RNR 15048, while lowest HI (43.9) was recorded in S1-JGL 24423.
Conclusion: Crop sown on 30thDecember revealed better performance in terms of grain yield under the present study during Rabi conditions. Among varieties, Ganga Kaveri (S2) performed better in terms of grain yield.
Awareness of Ergonomics in the Clinical Laboratory
Authors: Lawani-Luwaji E. U.  , Enebrayi Onitsha , Augustine Akhogba 
Published: October 2023

Aim: Clinical laboratory employees are highly susceptible to developing musculoskeletal disorders directly related to their job duties. This study assesses the level of ergonomics awareness among Medical Laboratory Scientist practitioners working across both public and private laboratories.
Study Design: A web-based system and program were employed online to produce, distribute, and assess surveys.
Place and Duration of Study: The survey was conducted from May 27 to June 6, 2023, among Medical Laboratory Scientists employed in private or government institutions in Bayelsa State, Nigeria.
Methodology: Structured questions about ergonomics were created to achieve research goals. Respondents were between 20 and 60 years.
Results Regardless of age, 85% of participants had good knowledge of ergonomics. Gender was found to impact knowledge, as demonstrated by a t-test.
Conclusion: Laboratory heads of departments and scientists must understand the importance of preventing injuries and acknowledge the potential for future discomfort, even if they are not currently experiencing any. Safety is a serious responsibility for everyone, and prioritising injury prevention is critical in laboratory environments.