bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autonomic Neuropathy in Ambulatory Type 2 Diabetes Mellitus Patients: A Single-arm Prospective, Observational Study
Authors: Saha Kaustav , Mukherjee Shatavisa , Maiti Animesh , Tripathi Santanu Kumar 
Published: December 2023

Abstract

Introduction:
Diabetic autonomic neuropathy (DAN), a serious complication of diabetes, is a significant contributor to increased morbidity and mortality. Although DAN often coexists with different peripheral neuropathies and other complications, it may also present in isolation. The present study aimed to understand the DAN status of a cohort of ambulatory type 2 diabetics in a tertiary care setting.

Methods:
A single-arm prospective observational study was carried out, where enrolled patients were interviewed for basic demographics and comorbidities, screened for symptoms of autonomic dysregulation, and other risk factors such as smoking and alcoholism. Based on the presence of overt symptoms, they were divided into two groups with or without any overt symptoms of autonomic neuropathy. Both groups were subjected to a battery of autonomic neuropathy tests, and their DAN status was characterized based on the observed scores.

Results:
The overall prevalence of DAN, as observed in our study, was 36%. Of 108 patients, 97 presented with one or more symptoms of autonomic dysregulation, whereas the rest, 10.1%, were without any symptoms. Among heart rate-based tests, a significant (P < 0.001) decrease followed by an increase in the Valsalva ratio was observed in 6 months and 12 months, respectively. A significant decrease (P < 0.001) in deep breathing test (E: I) values was observed in the 12th month. Most of the DAN patients presented with moderate autonomic dysfunction, followed by mild and severe, respectively. However, no significant change in DAN severity was noted with time.

Conclusion:
Using simple cardiovascular tests, DAN can be detected during the asymptomatic phase of the disease.
Cor triatriatum with Partial Anomalous Pulmonary Venous Connection: Role of Multimodal Imaging
Authors: Mital Tanya , Das Sambhunath , Devagourou V. 
Published: December 2023

Abstract
Both cor triatriatum (CorT) and partial anomalous pulmonary venous connection (PAPVC) come under the rare spectrum of congenital heart diseases. These entities may coexist in a patient or may appear independent of each other. The diagnosis is established routinely by echocardiography. Here, we describe the case of a 45-year-old female presenting with exertional dyspnea and palpitations. She was diagnosed to have CorT in the preoperative echocardiography; later, intraoperatively, transesophageal echocardiography revealed the additional presence of PAPVC with CorT. This case report highlights the limitations of echocardiographic findings in the patient and the importance of multimodal imaging techniques in such situations.
Acute Psychological Stress, Coronary Artery Spasm, Iatrogenic Coronary Dissection, In-stent Restenosis, and Atherosclerosis: A Rare Association of Multiple Etiologies for Recurrent Acute Coronary Syndrome
Authors: Jariwala Pankaj , Kulkarni Gururaj Pramod , Gude Dilip , Boorugu Hari Kishan , Punjani Arshad 
Published: December 2023

Abstract
Nonobstructive coronary artery lesions are seen in two-thirds of patients with angina and verified ischemia using a stress test who undergo coronary angiography. Ischaemia with no obstructed coronary artery disease (INOCA) is becoming more well recognized as a significant medical illness due to its relationship to decreased quality of life and an increased risk of cardiac events. This association between acute coronary syndrome (ACS) and high levels of psychological stress has been thoroughly investigated, and it has been found to be substantial. The microvascular function of the coronary arteries is endothelium-dependent, and this plays a role in how the heart reacts to psychological stress. Although coronary artery spasm (CAS) is likely to play a role in the etiology of INOCA, it is frequently misdiagnosed and underreported. In this article, we discuss a case of a young woman who came with recurrent ACS related to CAS, which was exacerbated by iatrogenic coronary dissection due to the presence of arteria lusoria, an atherosclerotic coronary artery disease leading to in-stent restenosis of the previous stent.
Cardiology Update December 2023: Key Takeaways from Landmark Trials
Authors: Kumar Devesh , Yadav Satyavir 
Published: December 2023

Abstract
Contemporary practice of cardiology is inspired by epistemological principles of Evidence Based Medicine. With rapidly evolving scientific data, it is imperative that clinicians are updated with the most recent evidence. We intend to review some of the most recent trials that may in the future impact our clinical practice. We discuss the most recent evidence on intra-vascular imaging, newer advances in heart failure, atrial fibrillation and conclude with a brief overview of trials in Structural Heart disease.
Assessment of frailty and its predictors in chronic obstructive pulmonary disease
Authors: Dutta Sharmistha , Goel Nitin , Kumar Raj 
Published: December 2023

Background:
Frailty represents a state of risk in which a relatively small stressor results in a disproportionate decline in health status. This study aims to determine the prevalence of frailty among patients with COPD in the Indian population and its associated risk factors.

Methods:
A descriptive cross-sectional study was conducted in 150 COPD patients. Frailty was assessed using the frailty phenotype method.

Results:
The mean age (SD) of the study population was 60.59 (5.9) years with 88.67% males and 53.33% ex-smokers. The prevalence of frailty was 51.33% (n = 77). Most of the frail patients belonged to GOLD group D (66.23%) (P < 0.0001). Post-bronchodilator FEV1(%) was lowest in the frail group (40 [36–47]%) (P < 0.0001). Risk of frailty significantly correlated with smoking pack years (1.036; 1.001–1.074), history of 1 exacerbation in last year (6.810; 2.036–22.779), post-bronchodilator FVC(%) (0.955; 0.926–0.985), post-bronchodilator FEV1(%) (0.940; 0.913–0.968), distance covered in 6-minute walk test [0.975; 0.965–0.986] and dyspnoea severity [1.044; 1.024–1.063]. In multivariate regression, 6-minute walk distance and GOLD group B were the independent predictors of frailty in COPD.

Conclusion:
The prevalence of frailty in Indian patients with COPD was 51.33%. Six-minute walk distance is an important predictor of frailty. Early identification of frailty will lead to prompt intervention and rehabilitation.
Effect of somatotypes on lung volumes, capacities and respiratory impedance: A pilot study
Authors: Jaiswal Kumar Nischay , Talwar Anjana , Vayyat Shyam , Bade Geetanjali G. 
Published: December 2023

Background:
The current morphological condition of an individual is described by a somatotype, which is a three-number scale. The endomorph, mesomorph and ectomorph components are presented in the same sequence, and each number corresponds to one of the three basic components of body composition.

Methods:
We recruited 50 healthy male subjects with a mean age of 24.10 ± 4.55 yrs. Somatotype was determined by the Heath and Carter method. Impulse oscillometry was performed followed by spirometry according to the European Respiratory Society (ERS) or American Thoracic Society (ATS) guidelines. Resistance at 5 Hz (R5) %pred, R20%pred, R5–R20, X5%pred, X20, area of reactance (Ax) and resonant frequency (Fres) were obtained by doing impulse oscillometry. Slow vital capacity (SVC), forced vital capacity (FVC), forced expiratory volume in the first second (FEV1), FEV1/FVC ratio and maximum mid-expiratory flow (MMEF) were assessed by doing spirometry.

Results:
Endomorphs (0.05 (0.00–0.09) vs 0.01 (0.00–0.04); P < 0.0001) and mesomorphs (0.04 (0.000.09) vs 0.01 (0.00–0.04); P = 0.002) had significantly higher R5–R20 than ectomorphs. Similarly, endomorphs (0.32 (0.07–0.82) vs 0.15 (0.08–0.35); P = 0.001) and mesomorphs (0.28 (0.17–0.64) vs 0.15 (0.08–0.35); P = 0.015) also showed significantly higher Ax than ectomorphs, Fres of endomorphs (15.37 (8.43–21.85) vs 10.08 (8.94–14.30); P < 0.0001) and mesomorphs (14.32 (10.24–20.86) vs 10.08 (8.94-14.30); P < 0.0001) were significantly high than ectomorphs. Moreover, spirometric measures reveal significant variation in which mesomorphs had significantly higher values of % predicted of FVC than ectomorphs (92.49 ± 7.211 vs 83.86 ± 7.861; P = 0.042) and the ratio of FEV1 to FVC was significantly higher in ectomorphs than in endomorphs (89.00 ± 5.80 vs 85.04 ± 5.73; P = 0.03).

Conclusion:
Peripheral airway dysfunction was observed in endomorphs and mesomorphs as compared to ectomorphs. Mesomorphs had a relatively higher FVC that may be due to their greater muscular strength.
Enhancing Academic Development: A reflexive exploration of Staff and Students’ Experiences on curriculum co-creation
Authors: Sebolao Rosaline Raseboya 
Published: December 2023

Academic development of students and staff is a critical element in higher education, especially with reference to their engagement in curriculum development. While higher education institutions advocate for the inclusion of students in curriculum co-creation, in practice, this has not been easily implemented. The urgency to create this collaborative ecosystem necessitates a reflexive contribution. In this article, I explore the experiences of academic staff and students on their engagement in curriculum co-creation with a specific focus on developing a study guide for the newly developed module, which is part of the decolonisation process. The emphasis on meta-cognitive skills and the social justice element in the curriculum development process ensures a responsive curriculum that meets the needs of society, students and staff in a cohesive and integrated manner. I underpin this reflective study on Schon’s theory of reflection on action. I argue that engaging students in curriculum creation stimulates deep learning, an empowerment attribute which I explore as it enhances innovative and critical thinking. This study employed qualitative methods of collecting and analysing data, followed by identifying important themes from the data. The reflections and emergent themes provide pathways to enhance academic development to encourage curricula co-creation processes in higher education.
Analisis Kebutuhan Pengembangan Kemampuan Speaking dan Listening Personel Pemandu Lalu Lintas Penerbangan Sesuai Ketentuan International Civil Aviation Organisation
Authors: Sonhaji Imam , Tri Saputra Surya , Rahajeng Larasati Emilia 
Published: December 2023

ICAO menetapkan bahwa bahasa inggris sebagai bahasa utama dalam komunikasi penerbangan antara pilot dan Air Traffic Controller (ATC), sehingga ATC wajib memiliki kemampuan ICAO English Proficiency (IELP) minimal level 4 (operasional level) dan dilakukan pengecekan setiap 3 tahun sekali, namun ditemukan pada saat tes pengecekan oleh rater, beberapa ATC di Indonesia tidak mencapai level 4 (operasional level). Penelitian ini bertujuan untuk menggali persepsi ATC terhadap IELP requirement serta isu yang menyertainya. Penelitian ini menggunakan metode penelitian survey melalui penyebaran angket, observasi dan wawancara kepada personil Rater IELP. Hasilnya adalah phraseology dan plain language memiliki fungsi yang berbeda pada kontek situasi penggunaanya, English plain language digunakan pada kondisi emergency atau abnormal condition, komponen pengujian yang paling susah adalah grammar bagi ATC Indonesia, kemampuan pendukung yang diperluakan ATC adalah writing dan reading, model pengaujian tatap muka masih menjadi unggulan, kualifikasi dari Interlocutors, Raters diharapakan adalah native speaker , ATC merasa kesulitas tes IELP sehingga membutuhkan persiapan pra tes karena pekerjaan ATC menggunakan English skill sebagai modal dasar seperti berkomunikasi dengan pilot, atau dengan adjacent unit dalam berkoordinasi., pengembangan model tes IELP lebih ditekankan pada pelatihan pra tes IELP.
Sistem Kontrol Kubikel Pada Panel Tegangan Menengah dengan Menggunakan Programmable Logic Controller
Authors: Simanjuntak Rossi Peter , Diriyanti Novalina Susi , Aulia Rahman 
Published: December 2023

Kubikel merupakan perangkat listrik yang berfungsi untuk mengendalikan, menghubungkan dan melindungi serta pembagi tenaga listrik dari sumber tenaga listrik. Sistem kontrol kubikel terhubung ke programmable logic controller (PLC) dengan tampilan graphical user interface (GUI) berbasis Supervisory Control and Data Acquisition (SCADA) serta menggunakan program Vijeo Citect. Com ethernet dipergunakan sebagai komunikasi data antara PLC dengan SCADA. Prinsip kerja sistem monitoring ini adalah PLC menerima perintah yang dikirimkan oleh teknisi melalui komputer, kondisi kubikel digambarkan dalam bentuk grafis berupa circuit sehingga memudahkan pengguna dalam pengoperasiannya. Jika pengguna menekan circuit untuk open atinya PLC menerima perintah logika “High” maka PLC memerintahkan agar kubikel terbuka dan sebaliknya jika pengguna menekan circuit untuk close artinya PLC menerima perintah logika “low” maka PLC memerintahkan kubikel tertutup. Dikarenakan perintah yang diberikan berasal dari pengguna maka untuk memastikan bahwa kubikel dalam kondisi open/close digunakan indikator lampu. Dalam percobaan diperoleh ketika pengguna menekan tombol open maka indikator lampu hijau akan menyala dan ketika ditekan tombol close maka indikator lampu merah akan menyala serta di layar komputer akan terlihat posisi circuit dalam kondisi open/close.. Hasil percobaan diperoleh bahwa sistem kendali kubikel yang dibangun sudah sesuai dengan perintah yang dijalankan dan sistem kendali tersebut telah berjalan dengan baik
Analysis of Clove Leaf Oil Distillation Business Income (Cloves Leaf Oil) In Matuo Sub-Village, Lelean Nono Village, Baolan District, Tolitoli Regency (Case Study of Tiga Jaya Essential Oil Refinery)
Authors: Ramlawati  , Hilmi  , Rani  
Published: December 2023

Analysis of Clove Leaf Oil Distillation Business Income (Clove Leaf Oil) in Matuo Sub-Village, Lelean Nono Village, Baolan District, Tolitoli Regency (Case Study of Tiga Jaya Essential Oil Distillation), This study aims to determine how much Clove Leaf Oil Distillation Business Income (Clove Leaf Oil) in Matuo Sub-Village, Lelean Nono Village, Baolan District, Tolitoli Regency (Case Study of Tiga Jaya Essential Oil Distillation). This research uses a qualitative research design. The data source is primary data, namely data obtained through interviews and documentation related to this research. The data analysis method used is descriptive qualitative and quantitative, namely production cost analysis, business revenue analysis, income analysis, and R / C Ratio efficiency level analysis.
After conducting research and discussions, it has been revealed that the Cloves Leaf Oil Distillation Business (Tiga Jaya Essential Oil Distillation) operating in Matuo Hamlet, Lelean Nono Village, Baolan District, Tolitoli Regency, During the 2022 period, a cloves leaf oil distillation business incurred a total cost of Rp. 993,196,500. The total revenue generated was Rp. 1,234,464,000. This indicates that the business earned a total income of Rp. 241,267,500 in one year. After conducting a case study of Tiga Jaya Essential Oil Distillation in Matuo Hamlet, Lelean Nono Village, Baolan District, Tolitoli Regency, the feasibility of Clove Leaf Oil Distillation Business for 2022 was found to have an R/C ratio of 1.24. The R/C Ratio of more than one indicates that the Cloves Leaf Oil Distillation Business located in Matuo Hamlet, Lelean Nono Village, Baolan District, Tolitoli Regency (as examined in the case study of Tiga Jaya Essential Oil Distillation) is viable and feasible
Determination of Irrigation water requirement and Scheduling of onion at Low land area of Wag-himra, Northern Ethiopia
Authors: Adane Messay Abera , Beza Gashaw , Wale Aemro 
Published: December 2023

Irrigation that saves water is important for satisfying the economic and environmental sustainability of commercial agriculture and improving the living standard of the people. Precision irrigation scheduling is critical to improving irrigation efficiency. A field experiment was conducted in two consecutive years at Abergelle irrigation schemes. The aim of the study was to determine crop water requirement and irrigation schedule of onion (when and how much to irrigate) for most market-oriented crops. The treatments were arranged with a factorial arrangement randomized complete block design with three replications. Three Levels of CROPWAT, fixed application depth (125%, 100%, and 75%ETc) and, three irrigation intervals (3, 4, and 5 days) and 1-farmer practice were used as control. The study result showed that 75% CROPWAT fixed depth at 3-day intervals achieved high water productivity, and saved 2873m3ha-1 of irrigation water compared with farmers’ method of irrigation. It provides additional irrigated land of 0.84 ha with a yield gain of 10.44 t ha-1. Therefore, a 3-day irrigation interval with 75% CROPWAT irrigation depth was recommended for the optimum yield and water productivity of the crop.
BELEDİYELERDE ÖLÇEK EKONOMİLERİNİN ETKİNLİK-VERİMLİLİK VE DEMOKRASİ-KATILIM BAĞLAMINDA KURAMSAL AÇIDAN TARTIŞILMASI
Authors: ÖZCAN SARIHAN Nazlı 
Published: December 2023

Belediyelere daha etkin ve verimli bir işlev kazandırmak gerekçesiyle yapılan reformların başında, iktisadi bir kuram olan ölçek ekonomileri yer almaktadır. Nüfus veya coğrafi alan açısından küçük ölçekli olarak değerlendirilen yerel yönetim birimlerinin mali yetersizlikleri ve diğer taraftan kaynak israfının önlenmesi, yerel yönetim birimlerindeki parçalı yapının ortadan kaldırılarak etkinlik, verimlilik ve bütünlüğün elde edilmesi ihtiyacı doğduğu düşünülmektedir. Bu bağlamda özellikle yerel kamu hizmetlerinin daha ekonomik bir şekilde sunulması adına ölçek kuramı kamu yönetimine entegre edilmeye çalışılmaktadır. Bunun sonucunda etkinlik ve verimlilik kavramlarının yanında hiç şüphesiz ki katılım ve demokrasi yönünden de ölçek ekonomileri kuramının yerel kamu hizmetlerinin sunumunda fayda sağlayıp sağlamadığı tartışmalı bir konu olarak karşımıza çıkmaktadır.
Bu çalışmada, yapılan literatür taraması neticesinde etkinlik-verimlilik ve demokrasi-katılım kavramları kısaca açıklanarak ölçek ekonomisi ile ilişkilerinin pozitif ve negatif açıdan değerlendirilip ortaya koyulması amaçlanmıştır. Bu kapsamda belediyelerde yapılan bu reformdan sonra birçok çalışmanın ve tartışmanın gündeme geldiği bunların değerlendirilmesi neticesinde ölçeğin genişlemesinin etkinlik ve verimlilik açısından belli bir noktaya kadar pozitif etkilerinin olabileceği fakat bu maliyet tasarrufları beklentisinin her durumda karşılığı olmadığı, katılım ve demokrasi açısından ise genel olarak negatif etkilerinin olduğu sonucuna ulaşılmaktadır.
Management of generalized anxiety disorder with lm potencies: a case report
Authors: Rana Dhanaraj Kumar , E K Ayisha , J Aiswarya 
Published: December 2023

Background: Generalized Anxiety Disorder (GAD) is a common mental health condition characterized by persistent and excessive worry or anxiety about various aspects of life, such as work, relationships, and daily activities. Anxiety disorders can result in work and school absences, posing a greater financial burden compared to other psychiatric disorders, given their higher global prevalence of approximately 642 million individuals affected. Although effective psychological treatments like Cognitive-Behavioral Therapy and mindfulness-based therapies exist for GAD, accessibility remains an issue for many. Common medications, including Selective Serotonin Reuptake Inhibitors and Benzodiazepines, carry potential side effects. While there has been some exploration of Homoeopathy's effectiveness in GAD, comprehensive discussions on the approach and posology are lacking.
Case summary: A 52-year-old female patient, exhibiting symptoms of generalized anxiety coupled with severe autonomic symptoms, was diagnosed with GAD based on DSM-5 criteria. The cases were systematically analyzed and treated with individualized homeopathic medicines in fifty millesimal potencies. The approach involved initial blood tests and thyroid function assessments to rule out systemic illnesses. Thorough case assessments were conducted using standardized record forms and the Kentian method to compile a comprehensive symptom profile. Following symptom analysis, RADAR Opus software was used for repertorization, leading to the prescription of Pulsatilla in 0/1 potency, determined by repertorial totality and final consultation with materia medica. Baseline severity and progress were assessed monthly using the Hamilton Anxiety Scale (HAM-A), while the World Health Organization Quality of Life brief version (WHO QOL BREF) was administered every six months. HAM-A scores, starting at 45, decreased to 3 at the end of the one-year observation period. The Modified Naranjo Criteria for Homeopathy—Causal Attribution Inventory was utilized to establish a causal relationship between Homoeopathic intervention and outcomes.
Conclusion: These findings provide preliminary evidence supporting the potential utility of fifty millesimal potencies of individualized homeopathic medicines in managing GAD. They underscore the need for further research in this area.
Pengaruh Rasio Keuangan dan Mekanisme Good Corporate Governance Terhadap Financial Distress
Authors: Prasetya Arifin , Hindasah Lela 
Published: December 2023

Tujuan penelitian ini adalah untuk menguji dan menganalisis pengaruh Profitabilitas, Likuiditas, Leverage, Komisaris Independen, Dewan Direksi, dan Keberagaman Gender terhadap Financial Distress dengan studi kasus pada Perusahaan Non Keuangan yang Terdaftar di Bursa Efek Indonesia Tahun 2019-2020 . Metode analisis data yang digunakan adalah analisis regresi logistik dengan bantuan software pengolahan data SPSS (Statistical Package For Social Science) versi 25. penelitian ini menunjukkan bahwa profitabilitas berpengaruh negatif signifikan terhadap Financial Distress, likuiditas tidak berpengaruh terhadap Financial Distress, leverage tidak berpengaruh terhadap Financial Distress, proporsi dewan komisaris independen tidak berpengaruh terhadap Financial Distress, dewan direksi berpengaruh negatif signifikan terhadap Financial Distress, dan keberagaman gender tidak berpengaruh terhadap Financial Distress.

The purpose of this research is to examine and analyze the effect of Profitability, Liquidity, Leverage, Independent Commisioners, Board of Directors, and Gender Diversity to Financial Distress with case studies on Non- Financial Companies Listed on the Indonesia Stock Exchange in 2019-2020. The data analysis method used is logistic regression analysis with the help of data processing software SPSS (Statistical Package For Social Science) version 25. this study indicate that profitability has a significant negative effect on Financial Distress, liquidity has no effect on Financial Distress, leverage has no effect on Financial Distress, proportion of independent commisioners has no effect on Financial Distress, board of directors has a significant negative effect on Financial Distress, and Gender Diversity has no effect on Financial Distress.