bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of bleaching treatments on the adhesion of orthodontic brackets: a systematic review
Authors: Boccuzzi Michela , Nota Alessandro , Cosola Saverio , De Simone Giada , Iozzo Rosa , Pittari Laura , Hwang Myoung Hwan , Bosco Floriana , Polizzi Elisabetta , Tecco Simona 
Published: October 2023

Abstract
Background
Nowadays bleaching procedures have gained popularity in orthodontic patients. Peroxide and Carbamide acids are the common agents which are used in in-office and at home bleaching techniques.
Consequently, the Bonding adhesion to the enamel can be influenced by the orthodontic phase and the residual peroxide might interfere with the polymerization and the adhesion of the brackets.
Frequent debonding of the brackets from teeth after the bleaching procedure could cause the lengthening of the therapy and promote irregularities on enamel surface derived from an additional bonding phase of the brackets.
The aim of this systematic review is to appraise the influence regarding the effect of the bleaching procedure on the bond strength of orthodontic brackets.

Methods
An electronic database search was performed. Search terms included: bleaching, brackets, adhesion; data were extracted and summarized. Risk of bias was assessed using the Chocrane risk of bias tool, adapted for in vitro studies.

Results
A total of 8689 articles were screened and 11 studies met the inclusion criteria of this systematic review.
1000 teeth of human and bovine origin were analyzed for the shear bond strength (SBS) of stainless and ceramic brackets after the bleaching treatments. All the authors divided the groups in different subgroups with different bleaching agents and in different concentration.
The SBS value allowed to demonstrate the necessity to delay the bonding of the brackets for two weeks after a bleaching treatment and its improvement when tooth mousse or antioxidants agents are used.

Conclusions
The SBS values and the delay of the bonding procedure must be considered in dental practice and clinical strategies are necessary in order to avoid drawbacks which could cause the debonding of the brackets after bleaching due to the alterations of the dental substrate, thus interfering with the orthodontic treatments.
Burnout and quality of life in Portuguese healthcare professionals working in oncology and palliative care—a preliminary study
Authors: Gonçalves Florbela , Gaudêncio Margarida 
Published: October 2023

Abstract
Background
Palliative care is an approach that improves the quality of life of patients and their families who are facing challenges associated with life-threatening illness, through the prevention and relief of suffering. Palliative care health professionals are considered a risk group for the development of burnout, since they live with severe disease and death, on a daily basis. With this work, the authors intend to evaluate the quality of life and risk of burnout in a group of health professionals, who work in a tertiary hospital dedicated to cancer patients.

Material and methods
The authors conducted a quantitative, descriptive, correlational and transversal study on palliative care professionals working with cancer patients. The evaluation protocol used to collect data included a sociodemographic questionnaire, WHO Quality of life Assessment instrument and Maslach Burnout Inventory. Statistical analysis was performed using the SPSS®Statistics program.

Results
In the sample, there is a predominance of female gender (79,4%) with a mean age of 43,2 ± 10,8 years. The most representative professional group was nursing (47,1%). The sample response rate was 91.9%. Analyzing Maslach Burnout Inventory score, it appears that physicians and nurses have higher levels of exhaustion when compared to the other groups. In relation to quality of life (QoL), it was observed that in all dimensions, there was a homogeneous distribution of responses. It was verified that it was not possible to establish any relationship between the dimensions of burnout and QoL. Thus, the various dimensions behaved independently.

Discussion
Physicians and nurses had the highest burnout levels in the most dimensions of Burnout score, in which they were followed by the operational assistants, who had moderate scores. Despite hight prevalence of Burnout, there is no correlation between Burnout and quality of life in this population. The perception of QoL is very satisfactory in the sample studied may result from the fact that these individuals have developed adequate self-protection strategies, thus preventing QoL from being affected by Burnout.

Conclusion
Prevention, diagnosis and intervention at burnout level is an important measure to be taken in health organizations, since the consequences that come from the experiences experienced by professionals will be reflected both in the quality of services provided to patients and in the QoL and well-being of professionals. Interventions are needed to promote better coping mechanisms when dealing with stress in this population. After this study, a Burnout Consultation was created at the Institution, to support professionals at risk or already affected.
Equine-assisted therapy effectiveness in improving emotion regulation, self-efficacy, and perceived self-esteem of patients suffering from substance use disorders
Authors: Souilm Nagwa 
Published: October 2023

AbstractSubstance Use Disorders (SUD) is a universal overwhelming public health problem and is associated with other psychological and mental health ailments such as emotion regulation, perceived self-esteem, and self-efficacy problems. Complementary and alternative medicine may be beneficial. The aim of this study was to assess the effectiveness of equine-assisted therapy in improving emotion regulation, self-efficacy, and perceived self-esteem among patients suffering from substance use disorders. It was carried out using a randomized controlled trial design at Behman hospital, Cairo, Egypt. It included 100 patients suffering from SUD attending the setting, equally randomized into an intervention group to receive the equine assisted therapy and a control group to receive the regular care. Data were collected using a self-administered questionnaire with standardized tools for assessment of emotion regulation, General Self-Efficacy (GSE), and perceived self-esteem. The intervention group received weekly equine-assisted therapy sessions over 6 weeks in addition to their standard regular therapy. Patients in both groups had similar demographic and SUD characteristics, as well as baseline scores of reappraisals, suppression, GSE and perceived self-esteem. At post-intervention, the intervention group had significant improvements in all these scores in comparison with the control group, as well as their baseline. The multivariate analysis identified the study intervention as a significant positive predictor of the reappraisal and GSE scores, and a negative predictor of the suppression and perceived self-esteem negative score. In conclusion, equine assisted-therapy as a complementary treatment in patients suffering from SUD is effective in improving their emotion regulation, self-efficacy, and perceived self-esteem. A wider use of this approach is recommended in SUD patients along with provision of needed facilities and resources, and training nurses in its administration. Further research is proposed to assess its long-term effectiveness. The clinical trial was registered in the “Clinical Trials.gov Protocol Registration and Results System (PRS);” registration number is (05632185/2022) and the full date of first registration is 10/11/2022.
Effects of emotion coaching group programme for mothers of preschool children with smart device overdependence: a mixed methods study
Authors: Lee Gumhee , Kim Sungjae 
Published: October 2023

Abstract
Background
Smart device overdependence adversely affects the overall development of preschool children. This study aimed to provide an emotion coaching group programme to mothers raising preschool children who are overly dependent on smart devices and to confirm the programme’s effectiveness.

Methods
This concurrent embedded mixed methods study used a non-equivalent control group pre-post design to verify the quantitative effect of the programme, and a descriptive research design to verify the qualitative effect. The study collected data from June 2019 to March 2021 from 51 (25 experimental, 26 control) mothers raising children aged 3–6 years in South Korea. The quantitative study examined the effects of an eight-session programme, conducted once a week for two hours, on mothers’ emotional intelligence, parenting behaviour, and their children’s attachment stability and smart device overdependence using a non-equivalent control group pre-post design. The analysis used a generalized estimate equation. For qualitative research, focus group interviews were used as a descriptive research design method, and content analysis was used for analysis.

Results
Quantitatively, the results showed significant differences between the experimental and control groups in terms of changes in maternal emotional intelligence (χ2 = 14.99, p = .001), maternal positive parenting behaviour (χ2 = 9.32, p = .009), children’s unstable attachment to their mothers (χ2 = 9.49, p = .009), and children’s overdependence on smart devices (χ2 = 14.48, p = .001). Qualitatively, the study derived five themes for the experiences of mothers who participated in the programme: “hope for desirable parenting without emotional difficulties,” “feelings touched by reflection,” “warm but authoritative parenting,” “children who became responsible by gaining psychological stability,” and “changed view of my home.”

Conclusions
The emotion coaching group programme was effective in improving the emotional intelligence and parenting behaviour of mothers raising preschool children. The programme also improved preschool children’s attachment stability to their mothers and overdependence on smart devices. The programme can be useful in community practice, and the present study can be used as evidence for education and research related to device overdependence.
Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer
Authors: Nimptsch Katharina , Aleksandrova Krasimira , Pham Thu Thi , Papadimitriou Nikos , Janke Jürgen , Christakoudi Sofia , Heath Alicia , Olsen Anja , Tjønneland Anne , Schulze Matthias B. , Katzke Verena , Kaaks Rudolf , van Guelpen Bethany , Harbs Justin , Palli Domenico , Macciotta Alessandra , Pasanisi Fabrizio , Yohar Sandra Milena Colorado , Guevara Marcela , Amiano Pilar , Grioni Sara , Jakszyn Paula Gabriela , Figueiredo Jane C. , Samadder N. Jewel , Li Christopher I. , Moreno Victor , Potter John D. , Schoen Robert E. , Um Caroline Y. , Weiderpass Elisabete , Jenab Mazda , Gunter Marc J. , Pischon Tobias 
Published: October 2023

Abstract
Background
Fatty acid binding protein 4 (FABP-4) is a lipid-binding adipokine upregulated in obesity, which may facilitate fatty acid supply for tumor growth and promote insulin resistance and inflammation and may thus play a role in colorectal cancer (CRC) development. We aimed to investigate the association between circulating FABP-4 and CRC and to assess potential causality using a Mendelian randomization (MR) approach.

Methods
The association between pre-diagnostic plasma measurements of FABP-4 and CRC risk was investigated in a nested case-control study in 1324 CRC cases and the same number of matched controls within the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. A two-sample Mendelian randomization study was conducted based on three genetic variants (1 cis, 2 trans) associated with circulating FABP-4 identified in a published genome-wide association study (discovery n = 20,436) and data from 58,131 CRC cases and 67,347 controls in the Genetics and Epidemiology of Colorectal Cancer Consortium, Colorectal Cancer Transdisciplinary Study, and Colon Cancer Family Registry.

Results
In conditional logistic regression models adjusted for potential confounders including body size, the estimated relative risk, RR (95% confidence interval, CI) per one standard deviation, SD (8.9 ng/mL) higher FABP-4 concentration was 1.01 (0.92, 1.12) overall, 0.95 (0.80, 1.13) in men and 1.09 (0.95, 1.25) in women. Genetically determined higher FABP-4 was not associated with colorectal cancer risk (RR per FABP-4 SD was 1.10 (0.95, 1.27) overall, 1.03 (0.84, 1.26) in men and 1.21 (0.98, 1.48) in women). However, in a cis-MR approach, a statistically significant association was observed in women (RR 1.56, 1.09, 2.23) but not overall (RR 1.23, 0.97, 1.57) or in men (0.99, 0.71, 1.37).

Conclusions
Taken together, these analyses provide no support for a causal role of circulating FABP-4 in the development of CRC, although the cis-MR provides some evidence for a positive association in women, which may deserve to be investigated further.
The impact of COVID-19 government policy on the international wine trade
Authors: Macedo Anthony , Rebelo João , Gouveia Sofia 
Published: October 2023

AbstractTo control the health impact of the COVID-19 pandemic, governments implemented various restrictive policies, such as stay-at-home orders and restrictions on internal movement, which had adverse effects on consumption and, consequently, on international trade. This was observed even for products intensively traded and minimally impacted in terms of production, such as wine. Thus, to work towards a better awareness of future crises, this study assesses the impact of government policy responses to COVID-19 on the international wine trade. A gravity model, a benchmark approach for studying the determinants of trade, is estimated using monthly data for 20 exporting countries and 214 potential importing countries. The findings suggest that, ceteris paribus, the value of wine export flows was inversely related to the intensity of government policy response in importing countries due to lower demand provoked by restrictive measures. This effect was considerably reduced, however, concerning wines coming from the Old World, which are inferred to be more resilient, a factor primarily attributed to their higher share of wines exported with geographical indications. On the other hand, only the exports from Old World countries were negatively influenced by restrictions on internal movements in the exporting country, which reflects a business model with a complex supply chain in which several intermediaries are involved, thus weakening the direct linkage between wine producers and consumers.
Childhood hyperactivity, eating behaviours, and executive functions: Their association with the development of eating-disorder symptoms in adolescence
Authors: Dufour Rachel , Breton Édith , Morin Alexandre J. S. , Côté Sylvana M. , Dubois Lise , Vitaro Frank , Boivin Michel , Tremblay Richard E. , Booij Linda 
Published: October 2023

AbstractBackgroundCross-sectional studies have shown that hyperactivity and impaired executive functioning are associated with symptoms of eating disorders in adolescence and adulthood. Whether hyperactivity and executive functions in early life can prospectively predict the emergence of eating disorder symptoms in adolescence remains unknown. The present study relies on a longitudinal design to investigate how hyperactivity at age 3, eating behaviours at age 3.5 and cognition at ages 3–6 were associated with the development of eating-disorder symptoms from 12 to 20 years old.MethodsUsing archival data collected since 1997 from the Quebec Longitudinal Study of Child Development cohort (N = 2, 223), we used Latent Curve Models to analyse predictors of youth’s trajectories of eating-disorder symptoms at four timepoints.ResultsA quadratic (curvilinear) trajectory of eating-disorder symptoms was found to be most representative of the data. Higher hyperactivity at age 3 was associated with higher levels of eating-disorder symptoms at age 12, and this association was partially mediated by higher levels of overeating and cognitive inflexibility in childhood. Cognitive inflexibility in childhood also mediated the association between hyperactivity at age 3 and increases in eating-disorder symptoms during adolescence. Furthermore, working memory was indirectly related to eating-disorder symptoms via the mediational role of cognitive flexibility.ConclusionsHyperactivity, overeating, cognitive inflexibility, and working memory early in life might precede the onset of eating-disorder symptoms in adolescence. Early behavioural and cognitive screening may help to identify children who are most at risk for eating disorders. This, in turn, could guide preventive interventions.
Discovery of a conical feature in Halmahera waters, Indonesia: traces of a late-stage hydrothermal activity
Authors: Alodia Gabriella , Nurhidayat  , Sobarudin Dyan P. , Adrianto Dian , Dwinovantyo Angga , Solikin Steven , Hanafi Mustafa , Pamumpuni Astyka , Kurniawan Idham A. , Poerbandono  , Green Chris M. , McCaig Andrew M. 
Published: October 2023

AbstractAn expedition to confirm the presence of underwater hazards was carried out in Halmahera waters, Indonesia, to the west of Halmahera Island from August to September 2021. The expedition carried out a multibeam survey, surface-towed magnetic survey, and seafloor sampling. A ~ 615-m-tall conical feature with traces of hydrothermal activity was discovered. The feature is bounded on the southeastern (SE) side by a series of normal faults at the peak, with possible dextral strike-slip faults traced west of the feature. The feature displays the potential presence of volcanic rocks based on the observed contrasting magnetic anomaly signature of down to − 100 nT, which at the magnetic equator corresponds to the presence of highly magnetised material. Four 2.5-D magnetic models were built to test various scenarios on the subsurface structure of the feature, mainly focusing on the presence of volcanic rocks at different epochs and a possible presence of serpentinisation. X-ray diffraction (XRD) of the silt and clay sediments sampled confirms traces of late-stage hydrothermal activity, indicated by a high percentage of quartz (53.87%), followed by calcite (34.56%), kaolinite (6.54%), and illite minerals (5.04%). Non-carbonate materials are yet to be found in the sampled sand and gravel sediments, which mainly consist of shell and coral fragments. The discovery of the conical feature, now termed the Yudo Sagoro Hill, provides new information on the structure and activities on the seafloor of Halmahera waters.
Subgrade soil stabilization using the Quicklime: a case study from Modjo- Hawassa highway, Central Ethiopia
Authors: Regasa Hailu , Jothimani Muralitharan , Oyda Yonas 
Published: October 2023

AbstractThis study examined the index properties, strength, and swelling pressure by mixing the Quicklime with five soil samples taken from the Meki-Abossa road section part of the Modjo- Hawassa highway. The main goal of this study was to provide more insight into the effects of Quicklime stabilization on the Atterberg limit like (LL, LP, and PI), OMC, MDD, CBR, and CBR swell percent of subgrade soil along the selected route alignment. Five disturbed samples were collected from the Meki-Abossa Road section to achieve the objectives. The samples were collected using the open pit sampling method with an average 1-1.5 m depth. Laboratory works were carried out for natural sub-grade soil and soil mixed with Quicklime. The natural sub-grade soil was classed as A-7-5 (38) by AASHTO and MH & CH by USCS, with a maximum LL of 75, PI of 41.6, MDD of 1.59, and OMC of 28, with CBR values less than five and CBR swell > 2%. The recommended lime (4%, 6%, and 8%) was mixed with the subgrade material. The result shows that the soil treated with Quicklime 4%, 6%, and 8% improved or lowered the untreated expansive soil plasticity index by 18.5%, 28.9%, and 23.8%, respectively, and increased OMC by 15.2% and reduced MDD by 18.23%. On the other hand, CBR values of the treated soil were increased by an average of 56.9%, with lower swelling potential decreases by 93.3%, higher workability, and stabilized soils were feasible to be used as subgrade material.
Challenging management of a baby with congenital multiple intestinal atresia, trisomy 18 and extremely low birth weight: a case report
Authors: Okamoto Mitsumasa , Fukushima Sachiyo , Okada Satoshi , Tsuruno Yudai , Fukuzawa Hiroaki , Ioroi Tomoaki , Kugo Masaaki 
Published: October 2023

Abstract
Background
Extremely low birth weight (< 1000 g) still influences postsurgical prognosis in the neonatal and infantile periods. Additionally, the life expectancy of neonates with trisomy 18 is extremely poor owing to various comorbidities. Therefore, it takes courage to perform laparotomy for the purpose of treatment of congenital multiple intestinal atresia in a baby with an unpredictable life prognosis.

Case presentation
Fetal ultrasonography revealed cardiac malformation, intestinal dilation, and physical characteristics suggestive of a chromosomal abnormality in this case. The patient was diagnosed with trisomy 18 after birth, with an extremely low birth weight. An atrial septal defect, ventricular septal defect, dilated jejunum, and a very thin collapsed small intestine were found on ultrasonography. With a diagnosis of congenital small intestinal atresia, a challenging laparotomy was done at 3 days of age, with jejunal atresia and multiple distal small intestinal atresia were observed. The jejunal end and distal small intestinal stump were separated into stomas at the wound edge. Hypertrophic pyloric stenosis developed at the age of 3 months and resolved with medication. The patient gained weight (2 kg) by daily stool injection into anal side of the intestine and decompression against poor peritonitis of dilated jejunum using enteral feeding tube for the long period. Finally, we could perform intestinal reconstruction safely and successfully at the age of 9 months.
Tracheotomy was performed due to difficulty in extubation associated with chronic lung disease. The patient was discharged at the age of 1 year and 3 months, and no major problems were noted at the age of 2 years.

Conclusions
We treat congenital intestinal atresia in extremely low birth weight infants with severe chromosomal abnormalities and severe cardiac malformations as follows: Stoma creation is performed quickly to avoid deterioration of the patient's hemodynamics. After that, while continuing enteric management, palliative cardiovascular surgery is performed as necessary, and the patient's body weight and intestinal tract status are determined to allow safe intestinal reconstruction.