bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intergenerational transmission of moral decision‐making inclinations
Authors: Chen Daili , Liu Chuanjun , Nolasco Edgar Emmanuel 
Published: February 2024

AbstractObjectiveThis study investigated the intergenerational transmission of utilitarian and deontological inclinations, examining whether these pass from parents to adult children and exploring the potential moderating effects of parenting style and intergenerational involvement in this process.BackgroundFamily factors, including religious norms and work values, influence moral development, but the intergenerational transmission of two moral inclinations—utilitarianism (emphasizing consequences, e.g., sacrificing one person to save five) and deontology (emphasizing intrinsic norms, e.g., refraining from intentionally harming the innocent)—remains underexplored.MethodWe measured these inclinations in 171 parent–adult child pairs using a moral decision thought experiment and questionnaires on parenting style and intergenerational involvement.ResultsPositive correlations emerged between parents and adult children for both inclinations. “Emotional warmth” in parenting style and intergenerational involvement showed significant negative moderating effects on the transmission of utilitarianism between generations.ConclusionThis study provides empirical evidence of intergenerational transmission of moral inclinations. Higher emotional warmth and increased intergenerational involvement inhibit the transmission of utilitarian inclinations, leading to reduced prioritization of better consequences.ImplicationsEnhanced emotional warmth and greater intergenerational involvement by parents can deter the transmission of utilitarian inclinations among adult children, prioritizing adherence to intrinsic norms over intentional harm for greater benefits.
Estimating fatigue life of carbon/epoxy composites: A rapid method coupling thermo‐mechanical analysis and residual strength
Authors: Demilly Kilian , Cavoit Jeanne , Marco Yann , Moreau Gurvan , Dolo Guillaume , Carrere Nicolas 
Published: February 2024

AbstractThe investigation of fatigue behavior typically involves time‐consuming tests, leading some researchers to explore methodologies based on self‐heating tests to reduce the process. For composite materials, the conventional approach involves piecewise linear approximations of the self‐heating curve and the stress transition between the first and second regimes is arbitrarily associated with a fatigue lifetime equal to 106 cycles. This paper proposes a novel methodology to address these simplifications. First, a non‐linear viscoelastic model is used to describe the self‐heating curve. Based on the mechanisms established in the literature, a link is proposed between the dissipation and the fatigue limit. The load leading to a significant contribution of non‐linear mechanisms is associated with an infinite life time. It allows the identification of an
–
curve and prediction of fatigue behavior through a minimal number of tests. The comparison with fatigue results is satisfactory.
A nomogram for predicting risk factors of testicular salvage after testicular torsion in children
Authors: Chen Pengyu , Huang Weipeng , He Yingying , Sun Mengkui , Sun Xuerui , Huang Yiyan , Li Shoulin 
Published: February 2024

ObjectivesThis study aimed to establish a nomogram for predicting the probability of testicular salvage after testicular torsion in children.MethodsWe retrospectively collected data of children with testicular torsion who were treated at Shenzhen Children's Hospital between September 2005 and August 2022. Of the training cohort, 113 patients who underwent orchiectomy and five with testicular atrophy after orchiopexy were included in the failed testicular salvage group. Additionally, 37 patients who underwent orchiopexy without postoperative testicular atrophy were included in the successful testicular salvage group. The predictive factors affecting testicular salvage were determined using univariate and multivariate logistic regression analyses; a nomogram was constructed. The nomogram was verified using data from the validation group.ResultsUsing multivariate logistic regression analysis, the independent risk factors of testicular salvage after testicular torsion were symptom duration (p = 0.034), intratesticular blood flow (p = 0.003), spermatic cord torsion degree (p = 0.037), and monocyte count (odds ratio: 0.012, p = 0.036). A nomogram was established based on these four risk factors. In the training cohort, the area under the receiver operating characteristic curve was 0.969. The area under the receiver operating characteristic curve of the verification cohort was 0.965, indicating good discrimination ability of the nomogram. Increased symptom duration without intratesticular blood flow increased the monocyte count and spermatic cord torsion degree and decreased the success rate of testicular salvage.ConclusionThis prediction model could obtain the corresponding probability of testicular salvage according to the clinical characteristics of different patients with testicular torsion, providing reference for clinicians and parents.
Ultrasound for acute pyelonephritis: a systematic review and meta‐analysis
Authors: Yu Jessica , Sri‐Ganeshan Muhuntha , Smit De Villiers , Mitra Biswadev 
Published: February 2024

AbstractBackgroundThere is little consensus regarding the indications and utility of urinary tract imaging and type of imaging to perform in patients presenting with acute pyelonephritis (APN).AimsThe aims of this systematic review were to, among patients with APN, (i) identify the proportion of patients investigated with ultrasound (US), (ii) identify the proportion of abnormal US and (iii) identify the proportion of patients with a change in management resulting from abnormal US.MethodsA comprehensive search covered two electronic databases (Medline and EMBASE), with selection of studies performed independently by two investigators. Inclusion criteria were English language APN diagnosis and quantification of patients assessed with US or abnormal US results. Quality appraisal used the Newcastle–Ottawa instrument.ResultsThere were 35 studies included. The proportion of patients assessed with US was reported in 16 manuscripts and ranged from 20% to 94%, with significant heterogeneity and publication bias. The proportion of abnormal US was reported in 31 manuscripts and ranged from 7% to 79%. The proportion of abnormal US leading to change in management was reported in five studies and ranged from 7% to 59%. There was marked heterogeneity among studies included in all three subgroups.ConclusionsPatients with APN are commonly investigated with US, but only a small proportion have abnormalities and appear to be associated with changes in clinical management. The use of routine US for APN is therefore questioned. The identification of clinical variables for appropriate selection of patients to investigate with US requires further research.
Biofilm therapy for chronic wounds
Authors: Liu Yang , Long Shengyong , Wang Hanfeng , Wang Yan 
Published: February 2024

AbstractChronic wounds have been a major factor of serious harm to global public health. At present, it is known that almost all chronic wounds contain biofilms, which seriously hinder the healing process. Removal of biofilms can effectively promote the healing of chronic wounds. As the study of wound biofilms deepens, many new treatment methods have emerged, thus bringing revolutionary means for the treatment of chronic wound biofilm. This review summarizes various methods for the treatment of chronic wound biofilm worldwide to provide a theoretical summary and practical basis for the selection of suitable wound biofilm treatment methods in clinical practice.
The sphingosine 1‐phosphate analogue, FTY720, modulates the lipidomic signature of the mouse hippocampus
Authors: Magalhães Daniela M. , Stewart Nicolas A. , Mampay Myrthe , Rolle Sara O. , Hall Chloe M. , Moeendarbary Emad , Flint Melanie S. , Sebastião Ana M. , Valente Cláudia A. , Dymond Marcus K. , Sheridan Graham K. 
Published: February 2024

AbstractThe small‐molecule drug, FTY720 (fingolimod), is a synthetic sphingosine 1‐phosphate (S1P) analogue currently used to treat relapsing–remitting multiple sclerosis in both adults and children. FTY720 can cross the blood–brain barrier (BBB) and, over time, accumulate in lipid‐rich areas of the central nervous system (CNS) by incorporating into phospholipid membranes. FTY720 has been shown to enhance cell membrane fluidity, which can modulate the functions of glial cells and neuronal populations involved in regulating behaviour. Moreover, direct modulation of S1P receptor‐mediated lipid signalling by FTY720 can impact homeostatic CNS physiology, including neurotransmitter release probability, the biophysical properties of synaptic membranes, ion channel and transmembrane receptor kinetics, and synaptic plasticity mechanisms. The aim of this study was to investigate how chronic FTY720 treatment alters the lipid composition of CNS tissue in adolescent mice at a key stage of brain maturation. We focused on the hippocampus, a brain region known to be important for learning, memory, and the processing of sensory and emotional stimuli. Using mass spectrometry‐based lipidomics, we discovered that FTY720 increases the fatty acid chain length of hydroxy‐phosphatidylcholine (PCOH) lipids in the mouse hippocampus. It also decreases PCOH monounsaturated fatty acids (MUFAs) and increases PCOH polyunsaturated fatty acids (PUFAs). A total of 99 lipid species were up‐regulated in the mouse hippocampus following 3 weeks of oral FTY720 exposure, whereas only 3 lipid species were down‐regulated. FTY720 also modulated anxiety‐like behaviours in young mice but did not affect spatial learning or memory formation. Our study presents a comprehensive overview of the lipid classes and lipid species that are altered in the hippocampus following chronic FTY720 exposure and provides novel insight into cellular and molecular mechanisms that may underlie the therapeutic or adverse effects of FTY720 in the central nervous system.image
The Rise of Communal Politics: Representing “Peasants” in Non‐electoral and Electoral Politics, Bengal 1920–1930s
Authors: Thivet Delphine 
Published: February 2024

AbstractThis article explores the representation of peasants in colonial India, during the 1920s‐1930s undivided Bengal. It examines how the historically marginalized and underrepresented rural population came to be constructed as objects of representation. It traces the development of representative claims made by various political parties and groups, both within and outside formal institutions of power, on behalf of rural society. The article discusses the challenges of categorizing the diverse rural population using the term "peasant" as an analytical category in the context of colonial Bengal. It highlights the dominance of the urban intelligentsia in provincial politics until the 1920s‐1930s, which neglected rural issues. It then explores the emergence of different claims to represent peasants in electoral politics, with a particular focus on the political debates surrounding the Tenancy Reform in Bengal. Drawing on secondary sources and colonial archives, it raises questions about how substantive representation of peasants occurred, who championed their representation, and how they formulated their demands. Overall, the article sheds light on the complex dynamics of peasant representation. By examining the rise communal peasant politics in 1920‐1930s Bengal, it contributes to a deeper understanding of the complexities of rural mobilization and the interplay between class and communal identities.
Microaggression and discrimination experiences among diverse youth with LGBTQ+ parents in the United States
Authors: Farr Rachel H. , Cashen Krystal K. , Siebenthaler Kelsey A. , Simon Kay A. 
Published: February 2024

AbstractFamily‐based microaggressions and discrimination experienced by youth with LGBTQ+ parents are important to understand from their perspectives. Using mixed methods, we examined such experiences among 12‐ to 25‐year‐old youth (N = 51) with at least one LGBTQ+ parent in the United States. Youth were diverse in race/ethnicity, family structure, gender and sexual identities, socioeconomic status, and geographic region. Using interviews, we explored LGBTQ+ family‐based microaggressions (reported through scale items with feedback) and discrimination (assessed via thematic analysis). Microaggressions and discrimination based on having LGBTQ+ parents were common, yet there were distinctions in direct and indirect stigma across the quantitative items and qualitative themes. These results underscore the value of mixed methods research with youth and implications for future research, practice, and policy.
Exploring the impacts of perceived locus of control on post‐traumatic stress disorder among disaster survivors: A systematic review
Authors: Güzel Aysun , Samancı Tekin Çiğdem , Uçan Yamaç Sabriye 
Published: February 2024

Accessible SummaryWhat is known on the subject?

It was previously reported that perceived external locus of control may exacerbate depressive symptoms, is associated with anxiety, boosts stress and general mental distress and weakens resilience against traumatic situations or difficulties.

What the paper adds to existing knowledge?

Those with a higher external locus of control are more prone to develop PTSD symptoms since the perceived external locus of control is among the predictors of PTSD. An internal locus of control is considered important in preventing PTSD, although an external locus of control appears to be a variable that causes/increases the prevalence of PTSD.

What are the implications for practice?

It is known that nurses are deployed in clinical and fieldwork during disaster and assume key roles both interventional practices and psychosocial education. Thus, it is of particular importance for mental health nurses to be aware of the locus of control in themselves, their colleagues, and the community before, during and after disasters to be able to combat the risk/presence of PTSD.

AbstractAimThe present systematic review explored the impacts of perceived locus of control on PTSD among individuals experiencing disasters.MethodThis is a systematic review study carried out through a search of the relevant research published in English over the period December 2021 to April 2022. Accordingly, we sought the studies to review on the Web of Science, PubMed, Scopus, Cochrane and Google Scholar databases using the keywords “Child, Children, Adolescent, Adolescence, Adult, Aged, Elderly, Post‐Traumatic Stress Disorder, PTSD, Internal‐External Control, Locus of Control, Disasters, Natural Disasters.”ResultsA total of 1.011 studies were found in the five databases using the keywords above. Following the exclusions, the remaining six studies were recruited for this systematic review. The six studies in question addressed earthquakes (2), hurricanes (1), wildfires (1), SARS (1) and fireworks explosions (1). In the study with wildfire survivors, there was a weak significant association between external locus of control and PTSD among those directly exposed to the disaster (r = .15, p < .01). The study with survivors of the SARS epidemic demonstrated that those with a high perceived chance (external) locus of control suffered PTSD (p = .001). An internal locus of control is considered important in preventing PTSD, although an external locus of control appears to be a variable that causes/increases the prevalence of PTSD.ConclusionIt was concluded that perceived locus of control is related to PTSD in individuals experiencing a disaster. The additional evidence was that post‐disaster PTSD among those with a high perceived external locus of control is stronger than those with a high perceived internal locus of control.
Effects of dietary supplementation with Haematococcus pluvialis on the growth, antioxidantase activities, and gut microbiota of Chinese mitten crab (Eriocheir sinensis)
Authors: Dou Yong , Bi Xiangdong 
Published: February 2024

AbstractThe Chinese mitten crab (Eriocheir sinensis) is bred extensively in Eastern and Northern China and faces a series of problems such as frequent diseases, germplasm degradation, and declining benefits, which have appeared to seriously affect the sustainable development of the cultivation industry. Haematococcus pluvialis, a type of unicellular green algae, have been proven to be the suitable dietary supplementation in crustacean feeds. After 14 days of feeding with 5% dietary supplementation with Haematococcus pluvialis powder, the growth, antioxidantase activities, and gut microbiota of E. sinensis were analyzed. The results indicated that H. pluvialis powder could significantly improve growth indicators including weight gain rate (WGR) and specific growth rate (SGR) of E. sinensis (p < 0.05). The levels of superoxide dismutase (SOD) and catalase (CAT) declined, while that of phenoloxidase (PO) kept rising under the treatment of H. pluvialis powder. Moreover, alkaline phosphatase (AKP) activity dropped initially and then increased. No significant differences in the Simpson index and Chao1 index in the control and H. pluvialis powder treatment were observed (p > 0.05). Although the dominant microbiota in the crab gut were not affected significantly by H. pluvialis powder, significant differences in the relative abundance of the dominant phyla between the control and H. pluvialis powder treatment groups were observed (p < 0.05). Furthermore, the relative abundance of Firmicutes and Candidatus_Bacilloplasma, which play an important role in the life activities of E. sinensis, were significantly higher in the group treated by H. pluvialis powder than in the control (p < 0.05). Therefore, the H. pluvialis powder could be potentially used not only as a rapid fattening regulator, but also to improve the immunity and metabolic capacity of E. sinensis.
Plasmodium falciparum transmission in the highlands of Ethiopia is driven by closely related and clonal parasites
Authors: Holzschuh Aurel , Ewnetu Yalemwork , Carlier Lise , Lerch Anita , Gerlovina Inna , Baker Sarah Cate , Yewhalaw Delenasaw , Haileselassie Werissaw , Berhane Nega , Lemma Wossenseged , Koepfli Cristian 
Published: February 2024

AbstractMalaria cases are frequently recorded in the Ethiopian highlands even at altitudes above 2000 m. The epidemiology of malaria in the Ethiopian highlands, and, in particular, the role of importation by human migration from the highly endemic lowlands is not well understood. We sequenced 187 Plasmodium falciparum samples from two sites in the Ethiopian highlands, Gondar (n = 159) and Ziway (n = 28), using a multiplexed droplet digital PCR (ddPCR)‐based amplicon sequencing method targeting 35 microhaplotypes and drug resistance loci. Here, we characterize the parasite population structure and genetic relatedness. We identify moderate parasite diversity (mean HE: 0.54) and low infection complexity (74.9% monoclonal). A significant percentage of infections share microhaplotypes, even across transmission seasons and sites, indicating persistent local transmission. We identify multiple clusters of clonal or near‐clonal infections, highlighting high genetic relatedness. Only 6.3% of individuals diagnosed with P. falciparum reported recent travel. Yet, in clonal or near‐clonal clusters, infections of travellers were frequently observed first in time, suggesting that parasites may have been imported and then transmitted locally. 31.1% of infections are pfhrp2‐deleted and 84.4% pfhrp3‐deleted, and 28.7% have pfhrp2/3 double deletions. Parasites with pfhrp2/3 deletions and wild‐type parasites are genetically distinct. Mutations associated with resistance to sulphadoxine–pyrimethamine or suggested to reduce sensitivity to lumefantrine are observed at near‐fixation. In conclusion, genomic data corroborate local transmission and the importance of intensified control in the Ethiopian highlands.
Artificial Intelligence: Arguments for Catastrophic Risk
Authors: Bales Adam , D'Alessandro William , Kirk‐Giannini Cameron Domenico 
Published: February 2024

AbstractRecent progress in artificial intelligence (AI) has drawn attention to the technology's transformative potential, including what some see as its prospects for causing large‐scale harm. We review two influential arguments purporting to show how AI could pose catastrophic risks. The first argument — theProblem of Power‐Seeking— claims that, under certain assumptions, advanced AI systems are likely to engage in dangerous power‐seeking behavior in pursuit of their goals. We review reasons for thinking that AI systems might seek power, that they might obtain it, that this could lead to catastrophe, and that we might build and deploy such systems anyway. The second argument claims that the development of human‐level AI will unlock rapid further progress, culminating in AI systems far more capable than any human — this is theSingularity Hypothesis. Power‐seeking behavior on the part of such systems might be particularly dangerous. We discuss a variety of objections to both arguments and conclude by assessing the state of the debate.
fMRI BOLD responses to film stimuli and their association with exhaled nitric oxide in asthma and health
Authors: Ritz Thomas , Kroll Juliet L. , Khan David A. , Yezhuvath Uma S. , Aslan Sina , Pinkham Amy , Rosenfield David , Brown E. Sherwood 
Published: February 2024

AbstractLittle is known about central nervous system (CNS) responses to emotional stimuli in asthma. Nitric oxide in exhaled breath (FENO) is elevated in asthma due to allergic immune processes, but endogenous nitric oxide is also known to modulate CNS activity. We measured fMRI blood oxygen‐dependent (BOLD) brain activation to negative (blood–injection–injury themes) and neutral films in 31 participants (15 with asthma). Regions‐of‐interest analysis was performed on key areas relevant to central adaptive control, threat processing, or salience networks, with dorsolateral prefrontal cortex (PFC), anterior insula, dorsal anterior cingulate cortex (dACC), amygdala, ventral striatum, ventral tegmentum, and periaqueductal gray, as well as top‐down modulation of emotion, with ventrolateral and ventromedial PFC. Both groups showed less BOLD deactivation from fixation cross‐baseline in the left anterior insula and bilateral ventromedial PFC for negative than neutral films, and for an additional number of areas, including the fusiform gyrus, for film versus recovery phases. Less deactivation during films followed by less recovery from deactivation was found in asthma compared to healthy controls. Changes in PCO2 did not explain these findings. FENO was positively related to BOLD activation in general, but more pronounced in healthy controls and more likely in neutral film processing. Thus, asthma is associated with altered processing of film stimuli across brain regions not limited to central adaptive control, threat processing, or salience networks. Higher levels of NO appear to facilitate CNS activity, but only in healthy controls, possibly due to allergy's masking effects on FENO.