bluuebunny/crossref_metadata_2025_split huggingface dataset:
Responsively Degradable Nanoarmor‐Assisted Super Resistance and Stable Colonization of Probiotics for Enhanced Inflammation‐Targeted Delivery
Authors: Zhu Limeng , Yu Tiantian , Wang Wenchao , Xu Tong , Geng Wujun , Li Na , Zan Xingjie 
Published: January 2024

AbstractManipulation of the gut microbiota using oral microecological preparations has shown great promise in treating various inflammatory disorders. However, delivering these preparations while maintaining their disease‐site specificity, stability, and therapeutic efficacy is highly challenging due to the dynamic changes associated with pathological microenvironments in the gastrointestinal tract. Herein, a superior armored probiotic with an inflammation‐targeting capacity is developed to enhance the efficacy and timely action of bacterial therapy against inflammatory bowel disease (IBD). The coating strategy exhibits suitability for diverse probiotic strains and has negligible influence on bacterial viability. This study demonstrates that these armored probiotics have ultraresistance to extreme intraluminal conditions and stable mucoadhesive capacity. Notably, the HA‐functionalized nanoarmor equips the probiotics with inflamed‐site targetability through multiple interactions, thus enhancing their efficacy in IBD therapy. Moreover, timely “awakening” of ingested probiotics through the responsive transferrin‐directed degradation of the nanoarmor at the site of inflammation is highly beneficial for bacterial therapy, which requires the bacterial cells to be fully functional. Given its easy preparation and favorable biocompatibility, the developed single‐cell coating approach provides an effective strategy for the advanced delivery of probiotics for biomedical applications at the cellular level.
Atomic‐Scale Visualization of Multiferroicity in Monolayer NiI2
Authors: Amini Mohammad , Fumega Adolfo O. , González‐Herrero Héctor , Vaňo Viliam , Kezilebieke Shawulienu , Lado Jose L. , Liljeroth Peter 
Published: January 2024

AbstractProgress in layered van der Waals materials has resulted in the discovery of ferromagnetic and ferroelectric materials down to the monolayer limit. Recently, evidence of the first purely 2D multiferroic material was reported in monolayer NiI2. However, probing multiferroicity with scattering‐based and optical bulk techniques is challenging on 2D materials, and experiments on the atomic scale are needed to fully characterize the multiferroic order at the monolayer limit. Here, scanning tunneling microscopy (STM) supported by density functional theory (DFT) calculations is used to probe and characterize the multiferroic order in monolayer NiI2. It is demonstrated that the type‐II multiferroic order displayed by NiI2, arising from the combination of a magnetic spin spiral order and a strong spin‐orbit coupling, allows probing the multiferroic order in the STM experiments. Moreover, the magnetoelectric coupling of NiI2 is directly probed by external electric field manipulation of the multiferroic domains. The findings establish a novel point of view to analyze magnetoelectric effects at the microscopic level, paving the way toward engineering new multiferroic orders in van der Waals materials and their heterostructures.
Tunable Nano‐Bending Structures of Loosened/Tightened Lassos with Bi‐Stable Vibration‐Induced Emissions for Multi‐Manipulations of White‐Light Emissions and Sensor Applications
Authors: Trung Nguyen Thanh , Chiu Chun‐Hao , Cuc Tu Thi Kim , Khang Trang Manh , Jalife Said , Nhien Pham Quoc , Hue Bui Thi Buu , Wu Judy I. , Li Yaw‐Kuen , Lin, Hong‐Cheu 
Published: January 2024

AbstractThe first tunable nano‐bending structures of [1]rotaxane containing a single‐fluorophoric N,N′‐diphenyl‐dihydrodibenzo[a,c]phenazine (DPAC) moiety (i.e., [1]RA) are developed as a loosened lasso structure to feature the bright white‐light emission [CIE (0.27, 0.33), Φ = 21.2%] in THF solution, where bi‐stable states of bending and twisted structures of DPAC unit in [1]RA produce cyan and orange emissions at 480 and 600 nm, respectively. With acid/base controls, tunable loosened/tightened nano‐loops of corresponding [1]rotaxanes (i.e., [1]RA/[1]RB) can be achieved via the shuttling of macrocycles reversibly, and thus to adjust their respective white‐light/cyan emissions, where the cyan emission of [1]RB is obtained due to the largest conformational constraint of DPAC moiety in its bending form of [1]RB with a tightened lasso structure. Additionally, the non‐interlocked analog M‐Boc only shows the orange emission, revealing the twisted form of DPAC fluorophore in M‐Boc without any conformational constraint. Moreover, the utilization of solvents (with different viscosities and polarities), temperatures, and water fractions could serve as effective tools to adjust the bi‐stable vibration‐induced emission (VIE) colors of [1]rotaxanes. Finally, tuning ratiometric emission colors of adaptive conformations of DPAC moieties by altering nano‐bending structures in [1]rotaxanes and external stimuli can be further developed as intelligent temperature and viscosity sensor materials.
Advanced Technologies and Applications of Robotic Soft Grippers
Authors: Qu Juntian , Yu Zhenping , Tang Wei , Xu Yining , Mao Baijin , Zhou Kunyu 
Published: January 2024

AbstractThe robotic soft gripper is a significant and expanding area of study. It is primarily a unique gadget that interacts with the external environment in a certain actuating mode by utilizing the properties of flexible materials and biological shape design. Robotic grippers are increasingly needed in the fields of medical operations, auxiliary maintenance, land rescue, underwater grasping, and space manipulation due to the increasing demand for automation. However, conventional rigid gripper is not the ideal option or optimal design for particular activities requiring a high degree of adaptation and interaction. The soft gripper can interact with its surroundings safely and flexibly because it is comprised of flexible materials. Currently, certain technical system has been developed through research on flexible grippers, but it is still in its infancy. This paper reviews the materials and manufacturing technology, actuating technology, and sensing and control technology of flexible mechanical grippers. Finally, several main application areas of soft grippers are discussed from a technical point of view, as well as possible challenges for further development.
Highly Customizable 3D Microelectrode Arrays for In Vitro and In Vivo Neuronal Tissue Recordings
Authors: Abu Shihada J. , Jung M. , Decke S. , Koschinski L. , Musall S. , Rincón Montes V. , Offenhäusser A. 
Published: January 2024

AbstractPlanar microelectrode arrays (MEAs) for – in vitro or in vivo – neuronal signal recordings lack the spatial resolution and sufficient signal‐to‐noise ratio (SNR) required for a detailed understanding of neural network function and synaptic plasticity. To overcome these limitations, a highly customizable three‐dimensional (3D) printing process is used in combination with thin film technology and a self‐aligned template‐assisted electrochemical deposition process to fabricate 3D‐printed‐based MEAs on stiff or flexible substrates. Devices with design flexibility and physical robustness are shown for recording neural activity in different in vitro and in vivo applications, achieving high‐aspect ratio 3D microelectrodes of up to 33:1. Here, MEAs successfully record neural activity in 3D neuronal cultures, retinal explants, and the cortex of living mice, thereby demonstrating the versatility of the 3D MEA while maintaining high‐quality neural recordings. Customizable 3D MEAs provide unique opportunities to study neural activity under regular or various pathological conditions, both in vitro and in vivo, and contribute to the development of drug screening and neuromodulation systems that can accurately monitor the activity of large neural networks over time.
Colloidal InAs Quantum Dot‐Based Infrared Optoelectronics Enabled by Universal Dual‐Ligand Passivation
Authors: Si Min‐Jae , Jee Seungin , Yang Minjung , Kim Dongeon , Ahn Yongnam , Lee Seungjin , Kim Changjo , Bae In‐Ho , Baek Se‐Woong 
Published: January 2024

AbstractSolution‐processed low‐bandgap semiconductors are crucial to next‐generation infrared (IR) detection for various applications, such as autonomous driving, virtual reality, recognitions, and quantum communications. In particular, III–V group colloidal quantum dots (CQDs) are interesting as nontoxic bandgap‐tunable materials and suitable for IR absorbers; however, the device performance is still lower than that of Pb‐based devices. Herein, a universal surface‐passivation method of InAs CQDs enabled by intermediate phase transfer (IPT), a preliminary process that exchanges native ligands with aromatic ligands on the CQD surface is presented. IPT yields highly stable CQD ink. In particular, desirable surface ligands with various reactivities can be obtained by dispersing them in green solvents. Furthermore, CQD near‐infrared (NIR) photodetectors are demonstrated using solution processes. Careful surface ligand control via IPT is revealed that enables the modulation of surface‐mediated photomultiplication, resulting in a notable gain control up to ≈10 with a fast rise/fall response time (≈12/36 ns). Considering the figure of merit (FOM), EQE versus response time (or −3 dB bandwidth), the optimal CQD photodiode yields one of the highest FOMs among all previously reported solution‐processed nontoxic semiconductors comprising organics, perovskites, and CQDs in the NIR wavelength range.
Synergistic Effect of Alkylammonium Chlorides to Trigger an Ultrafast Nucleation for Antisolvent‐Free Perovskite Solar Cells Processed from 2‐Methoxyethanol
Authors: Wu Xueyun , Zheng Yiting , Liang Jianghu , Tian Congcong , Sun Anxin , Tang Chen , Liu Yuan , Zhang Shimin , Wang Chenyang , Song Shuangxi , Chen Chun‐Chao , Reddy Kolan Madhav 
Published: January 2024

Abstract2‐Methoxyethanol (2ME), as a more environmentally friendly solvent with a lower boiling point compared to dimethylformamide, is ideal for the fabrication of perovskite solar cells (PSCs). However, when 2ME is used for antisolvent‐free deposition of perovskite films, an uncontrolled nucleation process and an easy phase transition to the δ‐phase often occur. Herein, an ultrafast nucleation process is developed using methylamine chloride (MACl) and n‐butylammonium chloride (BACl) as dual additives in 2ME without further solvent addition. While MACl can rapidly induce MACl‐based nuclei to initiate the nucleation process for formamidinium lead iodide (FAPbI3), the addition of BACl to the precursor with MACl can further increase the nucleation rate and density of nuclei, and bypass the transition from δ‐ to α‐phase during crystal growth to obtain a highly crystalline and pinhole‐free perovskite film. As a result, the FAPbI3 PSCs achieve a power conversion efficiency (PCE) of 23.6%. This work provides a new inspiration for controlling the crystal quality of perovskite thin films via nucleation rate suitable for upscaling.
Extended linear‐sigma model: transport properties of QCD matter at finite temperature
Authors: Tawfik Adel Nasser , Elshehri Azzah 
Published: January 2024

AbstractSince their discovery in heavy‐ion collisions, the transport properties of quantum chromodynamics (QCD) matter gained prominence among nuclear theorists. We introduce a new study based on a QCD‐like effective model. The thermal evolution of the electric and heat conductivity, and , respectively, and that if their ratios are evaluated in SU(3) extended linear‐sigma model (eLSM) with mean field approximation. Also, the bulk and shear viscosity normalized to the thermal entropy, and , respectively, as well as their ratios are estimated in the eLSM at finite temperature. Furthermore, the two ratios and are analyzed. The excellent agreement with recent lattice QCD calculations allows to draw the conclusion that the values assigned to the various eLSM‐parameters make this QCD‐like effective model capable of reproducing the non‐perturbative calculations of QCD matter, at finite temperatures.
The importance, benefits, and future of nanobiosensors for infectious diseases
Authors: Dhahi Th. S. , Dafhalla Alaa Kamal Yousif , Saad Sawsan Ali , Zayan Duria Mohammed Ibrahim , Ahmed Amira Elsir Tayfour , Elobaid Mohamed Elshaikh , Adam Tijjani , Gopinath Subash C. B. 
Published: January 2024

AbstractInfectious diseases, caused by pathogenic microorganisms such as bacteria, viruses, parasites, or fungi, are crucial for efficient disease management, reducing morbidity and mortality rates and controlling disease spread. Traditional laboratory‐based diagnostic methods face challenges such as high costs, time consumption, and a lack of trained personnel in resource‐poor settings. Diagnostic biosensors have gained momentum as a potential solution, offering advantages such as low cost, high sensitivity, ease of use, and portability. Nanobiosensors are a promising tool for detecting and diagnosing infectious diseases such as coronavirus disease, human immunodeficiency virus, and hepatitis. These sensors use nanostructured carbon nanotubes, graphene, and nanoparticles to detect specific biomarkers or pathogens. They operate through mechanisms like the lateral flow test platform, where a sample containing the biomarker or pathogen is applied to a test strip. If present, the sample binds to specific recognition probes on the strip, indicating a positive result. This binding event is visualized through a colored line. This review discusses the importance, benefits, and potential of nanobiosensors in detecting infectious diseases.
Regulating Polysulfide Transformation and Stabilizing Lithium Anode Using [PMo12O40]3− Cluster@Carbon Nanotube‐Modified Separator for Lithium‐Sulfur Batteries
Authors: Zhou He , Ma Zhiyuan , Yang Guang , Jiang Xinyuan , Duan Suqing , Wu Yuchao , Wang Mengyao , Ni Lubin , Feng Ligang , Diao Guowang 
Published: January 2024

AbstractLithium‐sulfur (Li−S) batteries emerge as compelling contenders for next‐generation energy‐storage devices, boasting a noteworthy mass‐specific energy of 2600 Wh kg−1. However, the cycle stability and commercialization of Li−S batteries encounter challenges because of polysulfide shuttle and uncontrolled lithium dendrite growth. In this study, we present a polyoxometalates‐based dual‐function [PMo12O40]3− cluster@carbon nanotube modified polypropylene (PP) separator (PMo12@CNT/PP) to regulate polysulfide transformation and safeguard the lithium anode in Li−S batteries. Leveraging its multi‐electron redox properties and stable cluster structure, the PMo12 cluster acts as a polysulfide mediator, effectively capturing and promoting electrochemical polysulfide transformation. The incorporation of CNT fosters consistent Li‐ion nucleation, stabilizes the lithium anode, and impedes dendrite formation throughout cycling. Hence, Li−S cells equipped with the PMo12@CNT/PP separator display higher capacity and better stability (675 mAh g−1 at 3.0 C and 0.02 % capacity decay per cycle over 700 cycles). The pouch cells with a sulfur loading 4.5 mg cm−2 exhibit an initial discharge specific capacity of 925 mAh g−1 at 0.1 C, and remain 849 mAh g−1 after 40 cycles, underscoring the significant potential for practical applications of Li−S batteries.
Failure Mechanism and Stability Enhancement Strategies for Self‐Supported Electrodes
Authors: Liu Fang‐bing , Sheng Meng‐di , Cong Lin‐chuan , Han Fu‐yu , Yang Jin , Meng Xin‐yu , Lin Hai‐bo , Lin Nan 
Published: January 2024

AbstractIn the face of global climate change and the need for energy diversification, electrocatalytic technology emerges as an eco‐friendly solution. However, persistent electrode failures hinder long‐term stability. This review comprehensively outlines the primary causes leading to the failure of self‐supported electrodes, encompassing substrate passivation, substrate/catalyst dissolution, CO poisoning, catalyst migration and agglomeration, as well as cathodic etching. Proposed strategies center on material design, emphasizing anchoring, lattice matching, substrate stability, and morphological control. Advanced characterization techniques and in situ technologies offer promising ways. The integrated deployment of these strategies will provide crucial guidance and support for the sustainable advancement of electrocatalytic technology.
Synergistic Brønsted Base/Photoredox‐Catalyzed Three‐Component Coupling with Malonates to Synthesize δ‐Hydroxy Esters and δ‐Keto Esters
Authors: Li Ting , Wang Wei , Dong Ming , Zhang Zhijie , Yu Sha , Chen Zhengchu , Wei Siping , Yi Dong 
Published: January 2024

Comprehensive SummaryMulticomponent alkene 1,2‐dicarbofunctionalizations (DCFs) have emerged as a powerful strategy to rapidly incorporate both two carbon subunits across one C—C double bond in one step for enhancing molecular complexity and diversity. To the best of our knowledge, there is only one report on photoredox‐catalyzed three‐component DCFs with malonates through the radical−radical cross‐coupling, while photoredox‐catalyzed radical‐polar crossover (RPC)‐type DCFs with malonates were still rare. Herein, we describe a redox‐neutral RPC‐type 1,2‐dialkylation of styrenes with malonates and aldehydes through the synergistic Brønsted base/photoredox catalysis system. This transition‐metal‐free strategy provides an efficient and clean approach to a broad variety of δ‐hydroxy esters and also features exceptionally mild conditions, wide compatibility of substrate scope and functional groups, and high atomic economy. Moreover, three‐component 1,2‐alkylacylation from the same starting materials was achieved in one‐pot manner through such RPC‐type coupling and subsequent two‐electron oxidation process, providing a set of δ‐keto esters of interest in pharmaceutical research.
In‐situ Oxidation and Coupling of Anilines towards Unsymmetric Azobenzenes Using Flow Chemistry
Authors: Griwatz Jan H. , Campi Chiara E. , Kunz Anne , Wegner Hermann A. 
Published: January 2024

AbstractMolecular switches, especially azobenzenes, are used in numerous applications, such as molecular solar thermal storage (MOST) systems and photopharmacology. The Baeyer‐Mills reaction of anilines and nitrosobenzenes has been established as an efficient synthetic method for non‐symmetric azobenzenes. However, nitrosobenzenes are not stable, depending on their substitution pattern and pose a health risk. An in‐situ oxidation of anilines with Oxone® was optimized under continuous flow conditions avoiding isolation and contact. The in‐situ generated nitrosobenzene derivatives were subjected to a telescoped Baeyer‐Mills reaction in flow. That way azobenzenes with a broad substituent spectrum were made accessible.
Understanding community provider practices in diagnosing and treating atypical anorexia nervosa: A mixed methods study
Authors: Johnson‐Munguia Sarah , Bottera Angeline R. , Vanzhula Irina , Forbush Kelsie T. , Gould Sara R. , Negi Sonakshi , Thomeczek Marianna L. , L'Insalata Alexa M. , Like Emily E. , Sharma Anjali R. , Morgan R. William , Rasheed Samiya 
Published: January 2024

AbstractObjectiveThere is a lack of consensus in defining “significant weight loss” when diagnosing atypical anorexia nervosa (atypical AN) and no guidelines exist for setting target weight (TW). The current study aimed to identify community providers’ practices related to the diagnosis of atypical AN and the determination of TW. A secondary aim was to evaluate whether professional discipline impacted “significant weight loss” definitions.MethodA variety of providers (N = 141; 96.4% female) completed an online survey pertaining to diagnostic and treatment practices with atypical AN. Descriptive statistics were computed to characterize provider‐based practices and Fisher's exact tests were used to test for differences in diagnostic practices by professional discipline. Thematic analysis was used to examine open‐ended questions.ResultsMost (63.97%) providers diagnosed atypical AN in the absence of any weight loss if other AN criteria were met, but doctoral‐level psychologists and medical professionals were less likely to do so compared to nutritional or other mental health professionals. Most providers found weight gain was only sometimes necessary for atypical AN recovery. Qualitative responses revealed providers found atypical AN to be a stigmatizing label that was not taken seriously. Providers preferred to use an individualized approach focused on behaviors, rather than weight when diagnosing and treating atypical AN.DiscussionLack of diagnostic clarity and concrete treatment guidelines for atypical AN may result in substantial deviations from the DSM‐5‐TR criteria in real‐world practice. Clinically useful diagnostic definitions for restrictive eating disorders and evidence‐based treatment guidelines for TW and/or other relevant recovery metrics are needed.Public SignificanceThe current study found variability in how community providers diagnose and determine target recovery weight for atypical anorexia nervosa (atypical AN). Many providers viewed the diagnosis of atypical AN as stigmatizing and preferred to focus on behaviors, rather than weight. This study underscores the importance of creating a clinically useful diagnostic definition and guidelines for recovery for atypical AN backed by empirical evidence that providers may implement in practice.
Ligand‐Protected Au52Cu72(SR)55 Nanoclusters Supported onto SBA‐15 by Electrostatic Attraction as Efficient and Stable Catalysts for Click Reaction
Authors: Li Xinghao , Fang Penghui , Li Xiaowu , Ajmal Sara , Zhou Xiaoxing , Sun Zhenjie , Song Yongbo , Zhu Manzhou , Li Peng 
Published: January 2024

AbstractAs heterogeneous catalysts, nanoclusters have been extensively investigated because of their exceptional catalytic performance. In this work, we propose an electrostatic attraction strategy to immobilize atomically precise positively charged [Au52Cu72(SR)55]+ (denoted as Au52Cu72(SR)55) nanoclusters supported onto negatively charged SBA‐15. As expected, the Au52Cu72(SR)55/SBA‐15 catalysts display outstanding activity for driving the benzyl azide‐phenylacetylene cycloaddition reaction (called as click reaction). In comparison to Au11/SBA‐15 and Cu13/SBA‐15 catalysts, the bimetallic Au52Cu72(SR)55/SBA‐15 catalysts exhibit the highest catalytic activity for click reaction. Moreover, to explore the effect of ligands on the catalytic performance of Au52Cu72(SR)55/SBA‐15 catalysts, Au52Cu72(SR)55/SBA‐15‐X (X is the heat treatment temperature, X=120, 250, 300) catalysts are obtained by calcining at different temperatures. Compared with Au52Cu72(SR)55/SBA‐15‐X (X=120, 250, 300), the uncalcined Au52Cu72(SR)55/SBA‐15 catalysts show the best recyclability for click reaction. The structural integrity of the Au52Cu72(SR)55 nanoclusters is a key factor contributing to their exceptional cyclic performance. This work will be valuable for designing an ideal ligand‐protected clusters‐based catalysts with superior performance for organic reactions.