bluuebunny/crossref_metadata_2025_split huggingface dataset:
The association between Big Five personality traits and social anxiety symptoms in Chinese college students: a network analysis
Authors: Xing Wanying , Liu Chang , Zhang Kan , Peng Yuan , Li Xinhong , Li Kuiliang , Wei Xinyi , Wu Shengjun , Ren Lei , Liu Xufeng 
Published: February 2024

Abstract

Background
The concept of social anxiety (SA) has long been recognized for its heterogeneity, with individual SA symptoms varying in their relationships with predisposing factors. Despite playing a prominent role in theoretical and empirical works on SA, studies investigating the specific links between Big Five personality traits and individual SA symptoms, remain limited. This study aims to explore these unique trait-to-symptom relationships among Chinese college students using network analysis.
Methods
A regularized graphical Gaussian model was estimated among 1,239 Chinese college students. The Chinese Big Five Personality Inventory-15 and the social anxity subscale of the Self-Consciousness Scale were used to assess personality traits and SA symptoms respectively. Bridge expected influence (BEI) was utilized to quantify the relative importance of each node within the network, while the network comparison test was conducted to explore potential sex differences in the Big Five-SA relationships.
Results
The study's findings unveiled distinct associations between Big Five traits and SA symptoms. Notably, the strogest edge is between Neuroticism and symptom "Get embarrassed very easily". Furthermore, Neuroticism was found to have a strong positive bridging effect on the SA symptom cluster, especially among females, while Extraversion have a strong negative bridging effect on the SA symptom cluster.
Conclusion
These results underscore the significant influence of Neuroticism as a potential target for interventions aimed at reducing SA, particularly among women. Furthermore, personalized care strategies base on individual symptom profiles should be considered.
Cognitive and Psychological Status of Methadone Maintenance Treatment Patients in Yunnan Province and Its Influencing Factors
Authors: Yang Wen , Luo Xiao , Bi Ke , Li Yuansen , Fan Xuan , Liu Xingyu , Hu Hongwei , Luo Huayou , Zhu Mei , Xu Yu 
Published: February 2024

Abstract
Background: Cognitive and psychological impairments are commonly found among heroin-dependent individuals receiving methadone maintenance treatment (MMT). This study investigates the screening methods and influencing factors of cognitive and psychological impairments in this population, aiming to improve treatment adherence and social functioning in MMT patients.
Methods: In a cross-sectional study conducted from December 2022 to December 2023, a total of 293 valid questionnaires were collected and included in the study. A questionnaire survey was conducted in Yunnan Province MMT outpatient clinic, including general sociological data, SCL-90(90-item Self-rating Scale for Symptoms) questionnaire to investigate the psychological status, MMSE (Mini-Mental State Examination) scale to assess the cognitive function, and analysis of the factors affecting the psychological cognition of the patients. The analyses were based in part on conventional statistical testing (t-test, χ2-test,and Binary logistic regression）.
Results: (1)In our sample, the prevalence of cognitive impairment was 52.2%, with a prevalence of depressive symptoms at 64.8% and anxiety symptoms at 54.3%;（2）Influencing factors of cognitive impairment in MMT subjects with different characteristics: age level differences was statistically significant. (P < 0.05); (3) The SCL-90 scale of MMT subjects showed a statistically significant difference in the nine factors of mental symptoms compared with the Chinese positive normal mode (P < 0.001);（4）The factors affecting depression of MMT subjects with different characteristics were statistically different: whether they lived alone (P < 0.05).
Conclusion: A significant proportion of Chinese patients undergoing MMT experience depression, anxiety, and cognitive impairments during the course of treatment. It is necessary to provide timely and effective psychological interventions for this high-risk population and control the influencing factors.
Impact of COVID-19 on the Management of Hypertension: A Perspective on Disease Severity, Service Use Patterns and Expenditures from Ghana’s Health Insurance Claims Data
Authors: Fenny Ama , Otieku Evans , Achiaw Samuel Owusu , Boye Bernard Okoe , Asenso-Boadi Francis , Addo-Cobbiah Vivian , Musah Mariam 
Published: February 2024

Abstract

Hypertension is a leading cause of death and morbidity in Ghana and other sub-Saharan African countries, but management has historically suffered from the fragility of health systems in these countries. This has been exacerbated by the COVID-19 pandemic and its associated measures. Our study examines and quantifies the effect of the pandemic on the management of hypertension in Ghana by determining changes in disease severity and presentation, as well as changes in service use patterns and expenditures. We used cross-sectional data to perform an impact evaluation of COVID-19 on hypertension management before and during the pandemic. We employed statistical tests to analyse medical claims data from Ghana’s National Health Insurance Authority database. The study duration includes a 12-month reference/pre-pandemic period (March 2019- February 2020) relative to the target/pandemic period (March 2020 - February 2021). We observed significant changes in health services use for hypertension during the pandemic. While there was a 20% reduction in the number of hypertension claimants in the pandemic year, there was an increase in hypertension severity as measured by the number of hypertension episodes per claimant (a 17.6% increase (95% CI. 15.0% – 20.3%; p = 0.031)). There was also an 18.64% or $22.88 (95% CI:$12 – $25, p = 0.01042) increase in the average cost per hypertension claimant in the pandemic year. The increase in episodes per claimant had the largest financial impact on the average cost per claimant. The findings from our studies are relevant for future policymaking and strategy implementation for hypertension control in Ghana.
Risk factors and prediction model for chronic thromboembolic pulmonary hypertension in acute pulmonary embolism patients with right heart dysfunction on CT or echocardiography
Authors: Li Shuangping , Huang Shenshen , Wang Wei , Gao Pengfei , Feng YUxuan , Mao Yimin 
Published: February 2024

Abstract
Objective
The aim of our study was to investigate the risk factors for chronic thromboembolic pulmonary hypertension (CTEPH) in acute pulmonary embolism patients with right heart dysfunction via computed tomography (CT) or echocardiography.
Method: Our study was a retrospective cohort study. A total of 506 patients diagnosed with pulmonary embolism at the First Affiliated Hospital of Henan University of Science and Technology between January 2018 and June 2023 were included, and 128 patients were ultimately included. The patients were divided into 33 suspected CTEPH patients and 95 non CTEPH patients. Multivariate logistic regression was used to analyse the risk factors for suspected CTEPH, and nomogram models were constructed according to the risk factors. ROC curves were used to analyse the predictive value of risk factors and the model for suspected CTEPH patients.
Results: The incidence of suspected CTEPH was 25.8% in acute pulmonary embolism patients with right heart dysfunction 3 to 6 months after PE diagnosis. No CTEPH occurred in patients treated after thrombolytic therapy. The time from symptom onset to treatment (OR, 1.20), sPESI score ≥ 1 (OR, 7.82), and baseline peak velocity of tricuspid regurgitation (OR, 4.17) were risk factors for suspected CTEPH in haemodynamically stable patients (p < 0.05). A prediction model was established based on these three variables. The AUC of the prediction model for suspected CTEPH was 0.905, which has high predictive value.
Conclusion: The incidence of suspected CTEPH is higher in patients with acute pulmonary embolism and right heart dysfunction according to CT or echocardiography. To improve the awareness of the diagnosis of acute pulmonary embolism, more active treatment and follow-up for patients with risk factors may reduce the incidence of CTEPH.
Analysing the intra and interregional components of spatial accessibility gravity model to capture the level of equity in the distribution of hospital services: does they influence patient mobility?
Authors: Pecoraro Fabrizio , Cellini Marco , Luzi Daniela , Clemente Fabrizio 
Published: February 2024

Abstract

Background An equal distribution of hospital structures represents an important factor to achieve Universal Health Coverage. Generally, the most diffused approach to measure the potential availability to healthcare is the provider-to-population ratio based on the number of beds or professionals. However, this approach considers only the availability of resources provided at regional or local level ignoring the spatial accessibility of interregional facilities that are particularly accessed by patients living at the borders. Aim of this study is to outline the distribution of the intra and interregional services to capture the level of equity across the country. Moreover, it explores the impact of the accessibility to these resources on interregional patient’s mobility to receive care. Methods To compute spatial accessibility, we propose an alternative approach that applies the enhanced two-step floating catchment area (ESFCA) to capture the level of attraction of intra and interregional hospitals to a given population. Moreover, the adoption of process and outcome indices captured to what extent the quality of structures influenced patients in choosing services located inside or outside their region of residence. Results The study confirms that there is an unequal distribution of high-quality resources at regional and national level with a high level of inequality in the availability and accessibility of quality resources between the north and south part of the country. This is particularly true considering the accessibility of intraregional resources in the southern part of the country that clearly influences patient choice and contribute to a significant cross border passive mobility to northern regions. This is confirmed by an econometric model that showed a significant effect of spatial accessibility with the propensity of patients of travel from the region of residence to receive care. Conclusions The analysis of intra and interregional components of spatial accessibility may contribute to identify to what extent patients are willing to travel outside their region of residence to access to care services. Moreover, it can contribute to gain a deeper understanding of the allocation of health resources providing input for policy makers on the basis of the principles of service accessibility in order to contain patient mobility.
Unveiling the Impact of Employee-Customer Familiarity on Customer Purchase Intentions: An Empirical Investigation within the Realm of Web-Based Date Analytics
Authors: Li Bingfeng , Xie Xiaoting , Qiao Shuang , Tan Shilei 
Published: February 2024

Abstract

This research delves into the intricate dynamics of employee-customer familiarity and its profound influence on customer purchase intentions within the burgeoning domain of web-based data analytics. In an era characterized by an increasingly digital marketplace, understanding the nuanced interactions between employees and customers is paramount for businesses striving to enhance customer relationships and drive purchase decisions. Drawing on empirical investigations, this study unravels the multifaceted facets of employee-customer familiarity, seeking to shed light on its implications for customer purchase intentions in the context of web-based data analytics. In this paper, an empirical study investigates the influence of employee-customer familiarity on customers' purchase intention for the home bedding industry, summarizes the current situation, puts forward research hypotheses and constructs a model of the effect of employee-customer familiarity on purchase intention was constructed. The familiarity of buyers and sellers was evaluated through a customer questionnaire, which provided subjective insights into the strength of interpersonal relationships. Meanwhile, confidence analysis, ANOVA (analysis of variance), correlation analysis and regression analysis were conducted on the survey data to explore the actual effects of these relationships on customers' purchase intention, and the positive effects of the five hypotheses on purchase intention were investigated. The anticipated findings suggest that increasing employee-customer familiarity positively impacts customers' purchase intentions, thereby illuminating the critical role of personalized interactions in driving business outcomes purchase intention, and the positive effects of the five hypotheses on purchase intention were investigated. The anticipated findings suggest that increasing employee-customer familiarity positively impacts customers’ purchase intentions, thereby illuminating the critical role of personalized interactions in driving business outcomes. Furthermore, the study sought to reveal the nuances of this relationship, recognizing the potential impact of different customer characteristics and industry contexts. Practical implications center on guiding companies in aligning their strategies to improve customer satisfaction and loyalty. From staff training programmes to targeted marketing campaigns, from brand influence to web e-commerce platform optimisation, businesses can use the insights gained from this research to build more meaningful connections with their customers. Building more meaningful connections with customers.
Unraveling Delays: Investigating Heterogeneous Hybrid Cluster Routing in Mobile Ad-hoc Networks
Authors: Balakrishnan Sreedevi , Sriniva Barathi 
Published: February 2024

Abstract
The modified partial authority node of a heterogeneous hybrid cluster routing is an analysis on delay in MANET which has been developed using Markov chain model. Delay values are also obtained through simulation using NS2 tool. Comparison is made with the existing technique and the output shows that our approach achieves enhance in its throughput, PDR and CBR traffic. The delay obtained through simulation augers well with the Markov chain model.
PROCAL: A SHap-based approach to explain Random Forest predictions of COVID-19- Procalcitonin levels
Authors: Naldan Muhammet Emin , Kırboğa Kevser Kübra , Işık Mesut , Gülcü Oktay 
Published: February 2024

Abstract

In COVID-19, the inflammatory cytokine storm is a critical factor that increases the severity of the disease. Procalcitonin (PCT) is a costly, time-consuming and important biomarker involved in the cytokine storm that exacerbates the severity of COVID-19. This study aims to develop an algorithm that can predict the PCT value in an explainable and interpretable way using explainable artificial intelligence (XAI) methods. The dataset consists of 1068 COVID-19 patients registered at Erzurum Regional Research Center in Turkey between March 2020 and March 2021 (ethical decision number: 2023/3–17). The Permutation Feature Significance (PFI) method was used to identify essential features and build the model. Among the seven-machine learning (ML) models, RandomForestClassifier performed best. RandomForestClassifier's performance metrics training accuracy: 0.89, test accuracy: 0.88, precision: 0.91, recall: 0.88, F-1 score: 0.88, Brier score: 0.11, AUC (area under the curve): 0.935, confidence intervals: 0.877, 0.883. The importance of the features in the model's predictions was analysed with the Shapley additive annotation (SHap) method integrated into the model. The results showed that LDH U/L, CRP mg/L and lymphocytes are important in predicting PCT. This study showed that PCT plays a vital role in assessing the condition of COVID-19 patients, and XAI methods can be helpful in this assessment.
Infiltration -driven performance enhancement of poly-crystalline cathodes in all-solid-state batteries
Authors: Park Jun-Woo , Sung Junghwan , Heo Junyoung , Kim Dong-Hee , Gu Hawon , Jo Yung-Soo , Park Heetaek , Park Jun-Ho , Choi Jeong-Hee , Ha Yoon-Cheol , Kim Doohun 
Published: February 2024

Abstract

All-solid-state batteries (ASSBs) with adequately selected cathode materials exhibit a higher energy density and better safety than conventional lithium-ion batteries (LIBs ). Ni-rich layered cathodes are benchmark materials for traditional LIBs owing to their high energy density. Recent studies have highlighted the advantages of using crack-free, single-crystalline cathode materials in ASSBs . In this study, a scalable infiltration sheet-type process was used to fabricate composite electrodes with different cathode-material morphologies for ASSBs . Typically, crack-free single-crystalline materials exhibit a better retention performance and lower rate capability than polycrystalline cathode materials. In this study, Li6PS5Cl-infiltrated polycrystalline electrodes showed an excellent retention performance and rate capability. Galvanostatic intermittent titration technique analysis and transmission electron microscopy confirmed severe polarization and the presence of a rock-salt-structure layer in cathode particles, indicating side reactions within the layered structure of the material. In contrast, composite electrodes comprising polycrystalline cathode materials infiltrated with the solid electrolyte Li6PS5Cl showed an excellent electrochemical performance owing to intimate electrode–electrolyte interfacial contact. This study confirms the critical influence of interface engineering and material morphology on the overall performance and stability of ASSBs, and could facilitate the development of high-performance ASSBs in the future .
Towards Sustainable Rural Revitalization: A Multidimensional Evaluation of Rural Vitality in China's Traditional Villages
Authors: Jia Anqiang , Yun Xin , Zheng Xiaowen , Wen Xuan , Liang Xiaoxu , Yun Yingxia 
Published: February 2024

Abstract
Traditional villages constitute a significant component of China's rural heritage. In the context of national efforts to achieve sustainable rural revitalisation, there is a lack of comprehensive assessments of rural vitality that can evaluate the balance between the competing demands of heritage conservation and rural development. This study aims to address the gap by defining an evaluation index system, Rural Vitality Assessment (RVA), which comprehensively assesses both protective and developmental aspects while taking into account natural and cultural ecological factors. The study utilizes data from a total of 206 traditional villages located in Hebei Province and employs a model to classify and analyze both subjective evaluations collected by interview and questionnaire alongside objective data. The framework employed a combined weighting method to determine appropriate indicator weights, thus facilitating quantitative evaluation of the data obtained. The study shows that over 90% of traditional villages in Hebei Province exhibit an imbalance between protection and development, which could lead to gradual deactivation. Additionally, the spatial distribution of RVA outcomes shows polarization, with higher levels observed in the north and lower levels in the south. The study concludes that the RVA framework is an effective tool for analysing the vitality level, spatial distribution, and disadvantage indicators of villages at different zoning levels. The results can provide a reference for the formulation of targeted heritage protection and development planning strategies and further aid in the rational allocation of resources, helping to narrow the development gap between urban and rural areas.
MARCH5 promotes hepatocellular carcinoma progression by inducing p53 ubiquitination degradation
Authors: CAI xin , Gao jie , Zhang Huapeng , yan zhiping , Guo danfeng , zhang shuijun 
Published: February 2024

Abstract

Dysregulated MARCH5 expression and impaired autophagy have been reported separately in some cancers. However, their relationship has not been explored in hepatocellular carcinoma (HCC). Here, we report the up-regulated expression of MARCH5 in hepatocellular carcinoma (HCC) tissues. Biologically, We further demonstrated that MARCH5 stimulation promotes proliferation, migration and invansion of HCC cells in vitro and enhances tumourigenesis and metastasis in vivo. This phenotype could be reversed by knockdown of MARCH5. Mechanistically, MARCH5 activated hepatocellular carcinoma autophagy by inducing LC3I/LC3II conversion, which is essential for the biological function of MARCH5. We further demonstrated the interaction between MARCH5 and p53, which ubiquitinates degraded p53. in conclusion, MARCH5 promotes HCC proliferation, invasion, and migration by ubiquitinating p53 ubiquitination, adding an important layer to the linkage between MARCH5 and p53, which can be translated into a new targeted therapy.
Robotic assisted simple prostatectomy mitigates perioperative morbidity compared to open simple prostatectomy - a single institution report
Authors: Larsen Magnus , Giske Anneli , Roaldsen Marius , Gullan Dag , Aarsaether Erling 
Published: February 2024

Abstract

Background: European guidelines currently advocate to offer open simple prostatectomy to patients with a prostate volume above 80 mL who suffer from moderate to severe LUTS, if a transurethral enucleation technique cannot be provided. However, open simple prostatectomy is regarded as an invasive surgical method, which is associated with relatively high perioperative morbidity and longer hospital stays, when compared to minimally invasive procedures. The aim of the study was to compare perioperative data from the first 26 robotic assisted simple prostatectomy (RASP) cases to patients who were previously treated with open simple prostatectomy (OSP) at our department.
Methods: The patients were identified by a search for the respective procedure codes. In the OSP group the prostatic adenoma was enucleated directly through the prostatic capsule (Millin procedure), while the adenoma was approached through the bladder in the RASP group. Complications between the groups were assessed by the Clavien-Dindo classification system.
Results: 27 patients who previously were treated with OSP were identified and compared to the first 26 who underwent RASP. Bleeding volume was 585 ± 317 ml in the OSP group compared to 134 ± 73 ml in the RASP group (p<0.001), resulting in a larger drop in postoperative hemoglobin (3.5 ± 1.7 in the OSP group compared to 1.7 ± 1.1 in the RASP group, p<0.001). Blood transfusions were significantly higher in the OSP group (12) compared to the RASP group (none, p<0.05). Clavien-Dindo score of 2 or more within 30 days were higher in the OSP group (11) compared to the RASP group (none, p<0.001). The mean length of hospital stay was 5.5 days (range 2-18) in the OSP group compared to 1.6 days (range 1-5) in the RASP group (p<0.001).
Conclusions: The introduction of robotic assisted simple prostatectomy reduced perioperative morbidity at our department.