bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Neoliberal Organic Crisis: Constitutional Transitions and the Collapse of the Keynesian Social Pact
Authors: Losurdo Federico 
Published: October 2023

Abstract
This article deals with the concept of organic crisis from a legal and a constitutional point of view and compares the different forms of constitutional transitions that have taken place in Europe and in Latin America from authoritarian regime to democracy. The reappearance of forms of neo-fascism is the result of the collapse of the Keynesian social pact, due to the ascension of neoliberal rationality, which is based on the dogmas of financial stability and hyper-competitiveness. The concrete result has been that inequality in the global distribution of wealth has reached astronomical levels. The question must be asked whether the ineptitude of the ruling classes in addressing the dramatic health and socio-economic effects of the covid-19 pandemic signify a neoliberal organic crisis.
Grassroots Pedagogy: Practicing Justice in Collaborative Classrooms
Authors: Canella Gino 
Published: October 2023

Abstract
Most universities champion “community engagement” and “inclusion” as core values of their institutions. But what does it mean to meaningfully engage with communities, or to foster more inclusive learning environments? I address this question by reviewing my experiences co-teaching with communities and detailing the challenges I have encountered – building relationships, managing time constraints, and negotiating participants’ divergent expectations. I develop the concept of grassroots pedagogy, which argues that teaching grounded in radical honesty and social justice upends traditional notions of expertise, strengthens higher education’s commitment to service, and promotes a culture of democracy. Highlighting the voices of people who have historically been excluded from higher education may create more engaged and inclusive institutions, in turn helping universities live up to the values they profess.
The Performative (Bio)Politics of Bare Life: between Putinism and Shamanism
Authors: Makarychev Andrey 
Published: October 2023

Abstract
This article has two focal points and two protagonists. First, it aims to look at the case of the self-proclaimed rebellious Siberian shaman Alexandr Gabyshev who became known in Russia since 2019 as a public figure and an anti-Putin crusader. Secondly, Gabyshev’s political crusade made the Russian president himself – even if indirectly – part of the ensuing public narrative that popped up around the shaman. The key research question I wish to address in this article is how the inner and public meanings of Gabyshev’s actionist protest might be interpreted through the lens of political theories, and what does a combination of theoretical perspectives bring for academically unpacking the case?
French Adaptation of the Strengths Use Scale
Authors: Bressoud Nicolas , Shankland Rebecca , Dubreuil Philippe , Forest Jacques , Belleville Karel , Samson Andrea C. , Gay Philippe 
Published: October 2023

Background Positive psychology focuses on enhancing attitudes and behaviors that support well-being, with a key pillar being the use of psychological strengths for optimal functioning. This is linked to positive outcomes such as increased happiness and life satisfaction. Objective This study aimed to evaluate the psychometric validity of the French adaptation of the Strengths Use Scale (SUS), a self-report tool measuring how individuals use their strengths in daily life. The original SUS, developed by Govindji and Linley (2007), has not been thoroughly assessed across languages and cultures. Method The French SUS’s psychometric properties were examined using data from six independent French-speaking Canadian samples ( N = 1397). After removing cases with missing data, exploratory factor analysis (EFA) was conducted on a subsample to establish the optimal factor structure. Confirmatory factor analysis (CFA) was then performed to assess the factor structure’s goodness-of-fit. Results Both EFA and CFA supported a unidimensional structure of the scale. The French SUS demonstrated good internal consistency (α = .94). The one-factor model yielded an RMSEA of .122, indicating some model misspecification. However, allowing residuals of some items to covary improved the model fit (RMSEA = .077). Conclusion The adapted French SUS exhibits similar properties to the original and presents no new consistency issues. This study contributes to adapting and validating the SUS in French for research and clinical practice. Future research should focus on developing a shorter version by eliminating redundancies and adapting the scale for children to evaluate positive psychology interventions' efficacy in youth.
“The toxic substance has killed all ducks”: framing of chemical risks related to the 2021 summer flood in German news media
Authors: Völker Carolin , Friedrich Thomas , Kleespies Matthias W. , Marg Oskar , Schiwy Sabrina 
Published: October 2023

Abstract
Background
The public understanding of environmental issues, such as chemical pollution due to flooding, is reflected and shaped by media representations and how these issues are framed. This study aims to identify how local, regional, and national German newspapers pick up and frame the issue of chemical pollution and related environmental and health risks regarding the 2021 summer flood using content analysis.

Results
The analysis shows that chemical pollution is rarely addressed compared to other flood-related topics. We identified 189 newspaper articles published in the months following the flood, which specifically mention chemical emissions. Of these articles, 50 report only marginally on chemical pollution, while 36 focus on the factual description of chemical emissions without addressing the consequences of pollution. The remaining 103 articles address impacts of certain pollutants such as oil, pesticides, heavy metals, or dioxins. Using content analysis, we identified four narratives that were common in their broad storylines and used to create a problem frame: (i) Highlighting severe contamination of the environment with chemical pollutants causing serious environmental damage (31 articles), (ii) describing possible contamination but with uncertainty about the extent and consequences (39 articles), (iii) tending to give the all-clear and emphasizing that there is no severe long-term contamination (25 articles), and (iv) indicating continuous contamination that does not allow the all-clear to be given (8 articles).

Conclusions
The results suggest that flood-related chemical pollution does not receive much media attention. Where it does, coverage focuses primarily on the description of the “tangible parts” of pollution, and thus contamination by oil, depicted by both smell and oil streaks, is frequently addressed Articles indicating severe contamination suggest threats to human and environmental health as likely consequences. However, most articles only report the results of chemical monitoring in the contaminated regions, which are evaluated by experts. This contrasts with other topics of controversy related to the flood, such as climate change as a potential cause. In light of our study, we propose that media and science communication need to pay more attention to chemical pollution—in general and as a result of flood events.
Flagellin, a plant-defense-activating protein identified from Xanthomonas axonopodis pv. Dieffenbachiae invokes defense response in tobacco
Authors: Mani Tamilarasi , Joshi J. Beslin , Priyadharshini R. , Sharmila Jeya Sundara , Uthandi Sivakumar 
Published: October 2023

Abstract
Background
Secretome analysis is a valuable tool to study host-pathogen protein interactions and to identify new proteins that are important for plant health. Microbial signatures elicit defense responses in plants, and by that, the plant immune system gets triggered prior to pathogen infection. Functional properties of secretory proteins from Xanthomonas axonopodis pv. dieffenbachiae (Xad1) involved in priming plant immunity was evaluated.

Results
In this study, the secretome of Xad1 was analyzed under host plant extract-induced conditions, and mass spectroscopic analysis of differentially expressed protein was identified as plant-defense-activating protein viz., flagellin C (FliC). The flagellin and Flg22 peptides both elicited hypersensitive reaction (HR) in non-host tobacco, activated reactive oxygen species (ROS) scavenging enzymes, and increased pathogenesis-related (PR) gene expression viz., NPR1, PR1, and down-regulation of PR2 (β-1,3-glucanase). Protein docking studies revealed the Flg22 epitope of Xad1, a 22 amino acid peptide region in FliC that recognizes plant receptor FLS2 to initiate downstream defense signaling.

Conclusion
The flagellin or the Flg22 peptide from Xad1 was efficient in eliciting an HR in tobacco via salicylic acid (SA)-mediated defense signaling that subsequently triggers systemic immune response epigenetically. The insights from this study can be used for the development of bio-based products (small PAMPs) for plant immunity and health.
Mycothiol maintains the homeostasis and signalling of nitric oxide in Streptomyces coelicolor A3(2) M145
Authors: Yoshizumi Tomoki , Shibui Yukiko , Kogo Minori , Honma Sota , Ito Shinsaku , Yajima Shunsuke , Sasaki Yasuyuki 
Published: October 2023

Abstract
Background
Previous studies have revealed a nitric oxide (NO) metabolic cycle in which NO, nitrate (NO3−), and nitrite (NO2−) circulate. The NO produced in this cycle serves as a signalling molecule that regulates actinorhodin (ACT) production via the DevS/DevR NO-dependent two-component system (TCS) in Streptomyces coelicolor A3(2) M145. However, the mechanisms involved in the regulation of NO signalling in S. coelicolor have not yet been elucidated. Mycothiol (MSH), a thiol molecule produced by Actinomyces, is involved in the defence mechanisms against oxidative stress. Therefore, this study focused on the correlation between intracellular NO and MSH levels.

Results
To investigate the interaction of MSH with endogenously produced NO, we generated an S. coelicolor A3(2) strain deficient in MSH biosynthesis. This mutant strain exhibited a decrease in low-molecular-weight S-nitrosothiols and intracellular NO levels during culture compared to those of the wild-type strain. Moreover, the mutant strain exhibited reduced activity of the DevS/DevR TCS, a regulator of NO homeostasis and ACT production, from the early stage of culture, along with a decrease in ACT production compared to those of the wild-type strain.

Conclusions
This study suggests that MSH maintains intracellular NO homeostasis by forming S-nitrosomycothiol, which induces NO signalling. Finally, we propose a metabolic model in which MSH from endogenously produced NO facilitates the maintenance of both NO homeostasis and signalling in S. coelicolor A3(2) M145.
Omics analyses of Rehmannia glutinosa dedifferentiated and cambial meristematic cells reveal mechanisms of catalpol and indole alkaloid biosynthesis
Authors: Zhou Pengfei , Li Haihua , Lin Yujin , Zhou Yujun , Chen Yinzi , Li Yiheng , Li Xuan , Yan Hui , Lin Weiming , Xu Beilu , Deng Huiting , Qiu Xiaoqi 
Published: October 2023

AbstractBackgroundRehmannia glutinosais a rich source of terpenoids with a high medicinal reputation. The present study compared dedifferentiated cells (DDCs) and cambial meristematic cells (CMCs) cell cultures ofR. glutinosafor terpenoid (catalpol) and indole alkaloid (IA) biosynthesis. In this regard, we used widely targeted metabolomics and transcriptome sequencing approaches together with the comparison of cell morphology, cell death (%), and catalpol production at different time points.ResultsWe were able to identify CMCs based on their morphology and hypersensitivity to zeocin. CMCs showed higher dry weight content and better catalpol production compared to DDCs. The metabolome analysis revealed higher concentrations of IA, terpenoids, and catalpol in CMCs compared to DDCs. The transcriptome sequencing analysis showed that a total of 27,201 genes enriched in 139 pathways were differentially expressed. The higher catalpol concentration in CMCs is related to the expression changes in genes involved in acetyl-CoA and geranyl-PP biosynthesis, which are precursors for monoterpenoid biosynthesis. Moreover, the expressions of the four primary genes involved in monoterpenoid biosynthesis (NMD,CYP76A26,UGT6, andCYP76F14), along with a squalene monooxygenase, exhibit a strong association with the distinct catalpol biosynthesis. Contrarily, expression changes inAADC,STR, andRBGgenes were consistent with the IA biosynthesis. Finally, we discussed the phytohormone signaling and transcription factors in relation to observed changes in metabolome.ConclusionsOverall, our study provides novel data for improving the catalpol and IA biosynthesis inR. glutinosa.
Harnessing the metabolic modulatory and antioxidant power of 1-(3-Phenyl-Propyl) cyclopropane and melatonin in maintaining mango fruit quality and prolongation storage life
Authors: Khedr Emad Hamdy , Khedr Nagwa , Abdel-Haleem Mohamed 
Published: October 2023

Abstract
Background
The aim of this study was to compare and investigate the effects of 1-(3-phenyl-propyl) cyclopropene (PPCP) and melatonin (MT) as anti-ethylene agents on postharvest senescence, quality, chilling tolerance, and antioxidant metabolism in the mango fruit cv. “Keitt”. The study involved exposing the fruit to 20 μL L− 1 PPCP or 200 μM MT, in addition to a control group of untreated fruit, before storing them at 5 ± 1 °C for 28 d. The findings revealed that the treatments with PPCP and MT were effective in reducing chilling injury and preserving fruit quality when compared to the control group.

Results
The use of 20 μL L− 1 PPCP was an effective treatment in terms of mitigating chilling injury and preserving fruit quality for 28 d. This was attributed to the decrease in metabolic activity, specifically the respiration rate and the production of ethylene, which led to the maintenance of fruit firmness and bioactive compounds, energy metabolism, and antioxidant activity, such as ascorbic acid, total flavonoids, trolox equivalent antioxidant capacity, dehydroascorbate reductase, glutathione reductase activity, ATP, and ATPase activity. The study also found that the MT treatment at 200 μM was effective in reducing chilling injury and weight loss and improving membrane stability. Additionally, it led to a decrease in malondialdehyde content and electrolyte leakage, and the maintenance of fruit quality in terms of firmness, peel and pulp colour values for mango peel and pulp total carotenoid content, as well as phenylalanine ammonia lyase and tyrosine ammonia lyase activity. These findings indicate that PPCP and MT have the potential to be efficient treatments in maintaining mango quality and minimizing post-harvest losses.

Conclusion
The utilisation of treatments with 20 μL L− 1 of PPCP or 200 μM MT was found to effectively preserve the postharvest quality parameters, in terms of bioactive compounds, energy metabolism, and antioxidant activity, of mangoes cv. “Keitt” that were stored at 5 ± 1 °C for 28 d.
The effect of audiovisual feedback of monitor/defibrillators on percentage of appropriate compression depth and rate during cardiopulmonary resuscitation
Authors: Lee Hannah , Kim Jay , Joo Somin , Na Sang-Hoon , Lee Sangmin , Ko Sang-Bae , Lee Jinwoo , Oh Seung-Young , Ha Eun Jin , Ryu Ho Geol 
Published: October 2023

Abstract
Background
High quality cardiopulmonary resuscitation (CPR) is one of the key elements of the survival chain in cardiac arrest. Audiovisual feedback of chest compressions have been suggested to be beneficial by increasing the quality of CPR in the simulated cardiac arrests.

Methods
A prospective before and after study was performed to investigate the effect of a real-time audiovisual feedback system on CPR quality during in-hospital cardiac arrest in intensive care units from November 2018 to February 2022. In the feedback period, CPR was performed with the aid of the real-time audiovisual feedback system. The primary outcome was the percentage of compressions with both adequate depth (5.0–6.0 cm) and rate (100–120/minute).

Results
A total of 27,295 compressions in 30 cardiac arrests in the no-feedback period and 27,965 compressions in 30 arrests in the feedback period were analyzed. The percentage of compressions with both adequate depth and rate was 11.8% in the feedback period and 16.8% in the no-feedback period (P < 0.01). The percentage of compressions with adequate rate in the feedback period was lower than that in the no-feedback period (67.3% vs. 75.5%, P < 0.01). The percentage of beyond-target depth with the feedback was significantly higher than that without feedback (64.2% vs. 51.4%, P < 0.01).

Conclusion
Real-time audiovisual feedback system did not increase CPR quality and was associated with a higher percentage of compression depth deeper than the recommended 5.0–6.0 cm. It is essential to explore more effective ways of implementing feedback in real clinical settings to improve of the quality of CPR.

Trial registration
NCT03902873 (study start: Nov. 2018, initial release April 2019, retrospectively registered).
Health-system drivers influencing the continuum of care linkages for low-birth-weight infants at the different care levels in Ghana
Authors: Schuler Christina , Agbozo Faith , Ntow George Edward , Waldboth Veronika 
Published: October 2023

Abstract
Background
Low birth weight (LBW) is associated with short and long-term consequences including neonatal mortality and disability. Effective linkages in the continuum of care (CoC) for newborns at the health facility, community (primary care) and home care levels have a high tendency of minimizing adverse events associated with LBW. But it is unclear how these linkages work and what factors influence the CoC process in Ghana as literature is scarce on the views of health professionals and families of LBW infants regarding the CoC. Therefore, this study elicited the drivers influencing the CoC for LBW infants in Ghana and how linkages in the CoC could be strengthened to optimize quality of care.

Methods
A constructivist grounded theory study design was used. Data was collected between September 2020 to February 2021. A total of 25 interviews were conducted with 11 family members of LBW infants born in a secondary referral hospital in Ghana, 9 healthcare professionals and 7 healthcare managers. Audio recordings were transcribed verbatim, analyzed using initial and focused coding. Constant comparative techniques, theoretical memos, and diagramming were employed until theoretical saturation was determined.

Results
Emerging from the analysis was a theoretical model describing ten major themes along the care continuum for LBW infants, broadly categorized into health systems and family-systems drivers. In this paper, we focused on the former. Discharge, review, and referral systems were neither well-structured nor properly coordinated. Efficient dissemination and implementation of guidelines and supportive supervision contributed to higher staff motivation while insufficient investments and coordination of care activities limited training opportunities and human resource. A smooth transition between care levels is hampered by procedural, administrative, logistics, infrastructural and socio-economic barriers.

Conclusion
A coordinated care process established on effective communication across different care levels, referral planning, staff supervision, decreased staff shuffling, routine in-service training, staff motivation and institutional commitment are necessary to achieve an effective care continuum for LBW infants and their families.
Impact of stress and stress mindset on prevalence of cardiovascular disease risk factors among first responders
Authors: Hendricks Brian , Quinn Tyler D. , Price Bradley S. , Dotson Timothy , Claydon Elizabeth A. , Miller Rodney 
Published: October 2023

Abstract
Background
Psychological stress is recognized as an important modifiable risk factor for cardiovascular disease (CVD). Despite its potential significance, few to no studies have evaluated the association between stress, stress mindset, and CVD risk factors among rural first responders. The objectives of this study were to identify relationships between general stress, stress mindset, and CVD risk factors.

Methods
The study sample (n = 148) included those 18 years or older and who currently serve as a first responder, defined as either EMS, firefighter, or law enforcement. Questionnaires captured information on demographics, years of work experience as a first responder, multiple first responder occupations, general stress, stress mindset, and self-reported CVD risk factors. Data were analyzed using regression analyses.

Results
Findings suggest that first responders with a stress-is-negative mindset have significantly higher general stress levels (β = 2.20, p = 0.01). Of note, general stress was not a significant predictor of CVD risk factors (AOR = 1.00, 95%CI = 0.93, 1.08) included in our study. However, a negative stress mindset was statistically significant predictor of CVD risk factors (AOR = 2.82, 95%CI = 1.29, 6.41), after adjusting for general stress and other potential confounders.

Conclusions
Findings suggest that stress mindset is an independent predictor of stress and CVD risk factors among rural first responders. These results have the potential to inform educational and organization level interventions targeting stress appraisal for this vulnerable sub population of workers.
Comparison of diagnostic efficiency of detecting IgG and IgE with immunoassay method in diagnosing ABPA: a meta-analysis
Authors: Liu Anlin , Chen Wushu , Wei Yining , Liang Jinkai , Liao Shuhong , Chen Yijun , Li Yongming , Wang Xidong , Chen Weisi , Qiu Ye , Li Zhengtu , Ye Feng 
Published: October 2023

Abstract
Background
Hitherto, the bulk of diagnostic criteria regards Aspergillus-specific immunoglobulin E as a key item, and regard IgG as an auxiliary method in diagnose. Nevertheless, there is no conclusive study in summarize the performance of IgG and IgE diagnosing ABPA.

Methods
We conducted a systematic review to identify studies report results of IgE and IgG detection in diagnosing ABPA. QUADAS-2 tool was used to evaluate included studies, and we applied the HSROC model to calculate the pooled sensitivity and specificity. Deeks’ funnel was derived to evaluated the public bias of included studies, and Cochrane Q test and I2 statistic were used to test the heterogeneity.

Results
Eleven studies were included in this study (1127 subjects and 215 for IgE and IgG). Deeks’s test for IgE and IgG were 0.10 and 0.19. The pooled sensitivity and specificity for IgE were 0.83 (95%CI: 0.77, 0.90) and 0.89 (0.83, 0.94), and for IgG were 0.93 (0.87, 0.97) and 0.73 (0.62,0.82), with P value < 0.001. The PLR and NLR for IgE were 7.80 (5.03,12.10) and 0.19 (0.13,0.27), while for IgG were 3.45 (2.40,4.96) and 0.09 (0.05,0.17). The combined diagnostic odds ratio and diagnostic score were 41.49 (26.74,64.36) and3.73 (3.29,4.16) for IgE, respectively, and were 38.42 (19.23,76.79) and 3.65 (2.96,4.34) for IgG.

Conclusion
The sensitivity for IgG diagnosing ABPA is higher than IgE, while the specificity for IgE is higher. IgG might be able to play a more important role in filtering ABPA patients.