bluuebunny/crossref_metadata_2025_split huggingface dataset:
PERCEPÇÃO SOBRE ASPECTOS RELACIONADOS À MEMÓRIA E APRENDIZAGEM DA PESSOA IDOSA: UM EVENTO NA UNIVERSIDADE DA MATURIDADE
Authors: Parreira Vaz Guilherme , Barbosa Baptista Anderson 
Published: December 2023

O envelhecimento é um fenômeno que atinge a todos os seres humanos. Provoca diversas transformações, as quais afetam a aprendizagem e memória. O artigo tem como objetivo identificar e discutir seus principais impactos na aprendizagem e memória senil. Trata-se de um relato de experiência prática vivenciada por discentes do curso de Medicina da Universidade Federal do Tocantins (UFT), campus Palmas, na disciplina de Neuroanatomia. A metodologia empregada foi a observação, diálogo e registro de informações pelos alunos no decorrer da extensão universitária “Conhecendo o Sistema Nervoso”, realizada na Universidade da Maturidade vinculada à UFT. A ocorrência de esquecimentos e lapsos de memória foram queixas predominantes entre os mais de 40 idosos presentes. Por outro lado, a coordenação motora diminuída compromete atividades cotidianas, bem como o uso das tecnologias pelos mesmos. Todavia, a adequação de formas alternativas de aprendizagem, que na pessoa idosa é mais lenta, fez-se eficaz durante a execução do projeto, apontando a necessidade de aprimoramento do cuidado em saúde neste público. Dessa maneira, o ato de se envelhecer impacta a qualidade de vida de quem o vivencia. Exige adaptações como exercitar a memória, a inserção do idoso nas tecnologias da modernidade e a preservação de sua autonomia.
PALAVRAS-CHAVE: Aprendizagem. Envelhecimento. Memória.
EXPERIÊNCIAS PEDAGÓGICAS, FORMATIVAS E DIALÓGICAS DO PIP FILO
Authors: Soares das Chagas José , Henrique Lima Ferreira Gustavo , Sérgio Gomes Soares Paulo , José de Pinho Maria , Vieira da Silva Oderlani , Neves T. dos Santos Letícia , Santos Lopes Ígor , Adriano Luiz Maropo  , Bruno Marcelo de Paula Pires  , Pereira de Souza Weslley , João Vitor W. M. M. dos Santos  , Ana Luísa W. M. M. dos Santos  
Published: December 2023

O presente texto é um relato da experiência do Projeto de Inovação Pedagógica do curso de Filosofia (PIP FILO) da Universidade Federal do Tocantins. O projeto teve início em junho de 2021 e sua finalização em dezembro do mesmo ano. O intuito do projeto foi proporcionar a utilização de novas ferramentas digitais para as práticas pedagógicas de ensino. O conteúdo aqui descrito faz parte de um curso de formação digital promovido pelo PIP FILO e que contou com a colaboração do curso de Teatro e do Residência Pedagógica. O projeto se desenvolveu junto com um Tutor e com Monitores de Inovação Pedagógica (MIPs) por dois caminhos; (1) a utilização de ferramentas digitais como prática pedagógica por meio de cursos, oficinas, lives e palestras, (2) a realização de uma chuva de ideias que foi organizada no mindmeister, no qual restringindo-nos à pesquisa sobre fakes news atribuídas a Paulo Freire e que acrescentamos a essa pesquisa uma dose de humor dos cínicos gregos.
#PROJETO INOVAJOR: O JORNALISMO AFIRMANDO A ACESSIBILIDADE E A DIVERSIDADE ÉTNICA NA UFT
Authors: Reis de Araújo Jardeane , Duarte de Miranda Ana Luisa , De Almeida Aires Júnior Aristóteles , Franco Carlos Fernando , De Araújo Jardeane , Da Silva Carvalho Kaio Alexandre , Barbosa N. de S. Guerra Kauê , Araújo da Silva Kleidiane , Dias Karajá Amorim Mayla , De Albuquerque Caracristi Maria de Fátima 
Published: December 2023

O projeto Inovajor teve o objetivo promover o protagonismo dos acadêmicos e estimular o monitoramento de acesso aos conteúdos educativos, teóricos e habilidades técnicas para alunos com deficiência física, indígenas e quilombolas do curso de jornalismo da UFT. Promover canais de comunicação midiáticos que permitissem o protagonismo desses alunos, estimulando a troca de saberes e experiências de acessibilidade nas universidades, as inovações propostas por startups e empresas que promovem aplicativos e instrumentos para oferecer melhor qualidade de vida às pessoas com deficiência. A metodologia participativa permitiu a inserção de novos atores que foram decisivos para acrescentar experiências, principalmente para os alunos com baixa visão ou cegos. O resultado das ações dá mostras de que se obteve um resultado satisfatório tanto para os monitores e tutora, uma vez que aprofundaram as técnicas de produção jornalística, bem como para os alunos público-alvo do projeto, que participaram exitosamente da experiência com o Inovajor.
PALAVRAS-CHAVE: Inovação; Acessibilidade; Inclusão; Jornalismo.
STUDY OF THE PROLIFERATIVE ACTIVITY OF SACCHAROMYCES CEREVISIAE IN YEAST BIOTECHNOLOGY AND PHYSICO-CHEMICAL METHODS OF ITS DETERMINATION
Authors: Bielykh I. A. , Samoilenko S. І. , Bliznjuk O. N. , Masalitina N. Yu. , Belinska A. P. , Varankina O. O. , Chechui H. F. , Zviahintseva O. V. 
Published: December 2023

The article discusses the solution of issues related to increasing the efficiency of technological processes and ensuring the release of high-quality finished products, relevant for production based on the use of S. cerevisiae yeast. The paper identifies major reasons for the need to regulate yeast culture metabolism, considers existing practice and proposes methods of changing its metabolic activity. The purpose of the research is to create the classification of the supplements / preparations from different origin to improve yeast vital activity by adjusting its culture medium composition with the use of complex hierarchical faceted method.
The proliferative processes taking place in the yeast cell are quite easily regulated. Therefore, knowing the dependence between the specific conditions of the environment and certain aspects of the yeast culture's vital activity, it is possible to purposefully change its growth, development and metabolism. Creating and maintaining certain conditions for the cultivation of yeast allows you to control the course of the fermentation process.
The influence of biologically active substances on the proliferative activity of S. cerevisiae cells was investigated. Concentrations were determined and the regulatory effect of succinic and folic acid preparations on the proliferative activity of yeast cells was proven. A comparative analysis of influence of different concentrations of exogenous substances on microorganisms culture growth was carried out. The most optimal concentrations of drugs for activation of yeast cell division were determined: succinic acid/ascorbic acid – 0.0015/0.0002 mg/ml; folic acid – 0.006 mg/ml.
Specific growth rate of yeast during cultivation in 20 % sucrose solution with succinic/ascorbic and folic acid preparations was calculated. It was established that the highest specific rate of cell growth was observed in the complex preparation, which included three organic acids. It was established that the specific rate of yeast reproduction in the complex preparation increased by an average of 30–35 % relative to the control sample. Increase in specific growth rate by 20–25 % of yeast was also observed in the medium with folic acid, the addition of succinic/ascorbic acids did not significantly increase specific rate (by approximately 10 %) of the growth of the S. cerevisiae yeast culture. It has been established that biologically active substances have certain concentrations that activate cell division and contribute to their active development and critical limits at which the development and growth of yeast cells are inhibited.
Electrical properties of the base film heterosystem Al/ITO/polyimide/Al2O3 for capacitive converter
Authors: Zaitseva Liliia , Dobrozhan Andrii , Khrypunov Gennadiy , Khrypunov Mykhailo 
Published: December 2023

On the basis of the conducted structural studies of thin films, a structural and technological solution was developed and a thin film capacitive transducer was created for acoustic monitoring of metal products by a capacitive method. It was determined that along with the crystalline structure of the layers, it is also necessary to control the surface electrical resistance of the conductive ITO layer, the values of which determine the possibility of using such a structure as a coating of a capacitive converter without significant losses of the useful signal, and the dielectric permeability of the Al2O3 layer, which significantly affects the value of the useful signal With the help of the four-probe method, it was established that the surface electrical resistance (R□) of ITO layers under optimal deposition conditions is equal to 8–15 Ohm/□. The study of electric power Hall results indicate that the obtained value of specific electrical resistance is determined by the concentration of the main charge carriers from about 8.3·1020 cm–3 and the mobility of the main charge carriers at the level of 44 cm2/(V·s). The results of studies of dielectric properties indicate an increase in the value of the dielectric constant of the polyimide/Al2O3 structure, which is 8.5–11.5 relative to units, relative to the polyimide film (3–3.9 relative units) by approximately 3 times at frequencies of the exciting signal in the range of 10 Hz–10 MHz. This fact confirms the assumption about the possibility of increasing the dielectric constant of the interlayer due to the application of a thin layer of Al2O3 on the polyimide film. To confirm the possibility of increasing the sensitivity of the method due to the use of a capacitive transducer based on the Al/ITO/polyimide/Al2O3 structure, in comparison with classical transducers, a series of aluminium samples was studied at an oscillation frequency of 2.5 MHz. The value of the received signal when using a thin-film converter increases by 7.6 times compared to a classic converter, which correlates well with the measurements of dielectric permeability of dielectric layers and taking into account the decrease in the thickness of the dielectric layer. Thus, the increase in the sensitivity of the capacitive method in the case of using thin-film capacitive converters based on the Al/ITO/polyimide/Al2O3 structure is experimentally confirmed. The maximum amplitude of the acoustic displacement occurs at the edge of the plate, so studies were conducted on electrodes with cutouts, which made it possible to increase the acoustic signal twice for a large internal cutout.
Complete Repair of Osteonecrosis of the Femoral Head After Basicervical Femoral Neck Rotational Osteotomy
Authors: Zhang Zhendong , Cheng Hui , Luo Dianzhong , Zhang Hong 
Published: December 2023

Case:
We present a 28-year-old female patient who developed left hip pain and was diagnosed with osteonecrosis of the femoral head (ARCO stage II). The patient underwent a basicervical femoral neck rotational osteotomy (BFNRO) combining surgical hip dislocation technique and extended retinacular soft-tissue flap technique. She was followed up for 53 months and exhibited complete repair of the necrotic area, with normal hip range of motion, gait, and excellent hip functional scores.

Conclusion:
The BFNRO procedure, by rotating the necrotic area of the femoral head out of the weight-bearing zone, has the potential to achieve complete repair of the necrotic area.
CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair
Authors: Chen Jichao , Hassan Dalia 
Published: December 2023

Abstract

Cell plasticity theoretically extends to all possible cell types, but naturally decreases as cells differentiate, whereas injury-repair re-engages the developmental plasticity. Here we show that the lung alveolar type 2 (AT2)-specific transcription factor (TF), CEBPA, restricts AT2 cell plasticity in the mouse lung. AT2 cells undergo transcriptional and epigenetic maturation postnatally. Without CEBPA, both neonatal and mature AT2 cells reduce the AT2 program, but only the former reactivate the SOX9 progenitor program. Sendai virus infection bestows mature AT2 cells with neonatal plasticity where Cebpa mutant, but not wild type, AT2 cells express SOX9, as well as more readily proliferate and form KRT8/CLDN4+ transitional cells. CEBPA promotes the AT2 program by recruiting the lung lineage TF NKX2-1. The temporal change in CEBPA-dependent plasticity reflects AT2 cell developmental history. The ontogeny of AT2 cell plasticity and its transcriptional and epigenetic mechanisms have implications in lung regeneration and cancer.
Treating Corneal Epithelial Defects Using Dehydrated Human Amniotic Membrane-Derived Material: A Prospective Study
Authors: Ho Derek Kwun-hong , Holland Lee , Elhaddad Omar , Tole Derek , Darcy Kieren 
Published: December 2023

Abstract
Background The human amniotic membrane (hAM) holds promise as a graft material owing to its anti-inflammatory properties. The aim of this study is to assess the effectiveness of dehydrated hAM-derived material (DHAMM) as a temporary patch for treating persistent corneal epithelial defects (PCED) of various aetiologies. The study is conducted at a UK based tertiary corneal unit to evaluate DHAMM's potential and efficacy as a treatment option.Methods This was a single-site prospective clinical study on DHAMM application at Bristol Eye Hospital between August 2022 and June 2023. All patients, when possible, received serial slit lamp photography for objective documentation of epithelial defect size changes over time.Results A total of 17 patients with corneal epithelial defects received DHAMM as a temporary patch. Successful resolution was observed in 94.1% of cases, with an average healing time of 27.1 days. Neurotrophic keratitis was the most common cause of PCED. Although neurotrophic ulcers took longer to heal compared to non-neurotrophic ulcers, the difference was not statistically significant. The average corneal epithelium healing rate was 1.47 ± 2.48 mm²/day. DHAMM application was well-tolerated with no complications observed.Conclusions Our study demonstrated a high success rate in closing epithelial defects using DHAMM. Early application of DHAMM in the course of the disease may contribute to its efficacy. Corneal re-epithelialisation rate represents an objective outcome measure for comparing between different treatment options. The study highlights DHAMM as a valuable treatment option for managing PCED and preventing severe complications and vision loss.
ENSO's Signature on the Estimation of Cloud Feedback to Global Warming
Authors: Koren Ilan , Liu Huan , Altaratz Orit 
Published: December 2023

Abstract

Detection of trends in cloud properties and radiative effects is crucial for understanding the climate and predicting its future state. The El Niño-Southern Oscillation (ENSO), a climate phenomenon affecting temperature and clouds globally, can obscure the detection of cloud feedback to global warming. Therefore, accurately decoupling ENSO's signature is crucial. To investigate this issue, we analyzed 72 years of reanalysis data (01.1950–12.2021) and 19 years of satellite observations (12.2002–11.2021). The results suggest that: (1) ENSO is the primary driver of the changes in deseasonalized monthly cloud fraction, cloud top temperature, and cloud optical depth during 12.2002–11.2021; (2) depending on the analysis method and regions of interest, ENSO can introduce a significant bias (≥ 1 W m-2 ℃-1) into cloud feedback estimations over periods even longer than 50 years; and consequently (3) it is crucial to account for and decouple ENSO-related variations when estimating cloud feedback, particularly in tropical regions or during short periods characterized by intense ENSO activity.
Utilizing a Floating Sleeve Antenna for Interstitial Microwave Hyperthermia Treatment of Superficial and Deep-seated Breast Tumors
Authors: Eltigani Faihaa , Ahmed Sulafa 
Published: December 2023

Abstract

Purpose: Breast cancer is a leading cause of mortality among women worldwide. While chemotherapy and radiotherapy are commonly used treatment modalities, they have several side effects that can negatively impact the patient. In this study, we explore the application of a floating sleeve antenna for interstitial microwave hyperthermia for breast tumors.
Method: Two distinct 3D breast models were employed: a simplified semi-spherical and a highly detailed anatomical model. Both models featured superficial and deep-seated tumors. The floating sleeve antenna was inserted into the breast models, and simulations were con-ducted to assess the specific absorption rate (SAR) and temperature distribution.
Results: In the simple model, the superficial tumor reached a maximum temperature of 50.7 ºC, while the deep-seated tumor maintained a uniform temperature of 48.9 ºC. In contrast, the realistic model achieved a maximum temperature of 46.2 ºC for the superficial tumor and 41.47 ºC for the deep-seated tumor within the same 15-minute treatment period. These results demonstrate the ability of the antenna to attain the desired hyperthermia temperatures (above 39 °C to 45 °C).
Conclusion: microwave hyperthermia using a floating sleeve antenna has the potential to be an effective and safe alternative treatment for breast cancer with minimal side effects
To scrounge or not to scrounge? An evolutionary game-theoretical result on the integration of marginalist food-sharing models
Authors: Pinheiro Marcos Paiva 
Published: December 2023

Abstract
Behavioral ecologists believe that a substantial portion of variability in observed human food transfers derive from marginal value asymmetries in resource acquisition and can be explained with the help of tolerated scrounging, kin selection and reciprocal exchange models. For this belief to be true, however, it must be shown whether and to what extent these models might be integrated into a coherently unified explanation of resource sharing behavior. In this contribution, I combine marginalist analysis with evolutionary game theory to show that, contrary to the conventional view, these models cannot be usefully integrated. Given the option to scrounge a producer's acquisition or respect her ownership, natural selection should predispose individuals to adopt a pure scrounging strategy that leads to the equalization of marginal value differences in consumption. Reviewing the empirical evidence with a focus on recent agent-based models that illuminate the complex dynamics of scrounging behavior, I show that the pure scrounging equilibrium hypothesis is (i) able to predict node-level data describing the scale and scope of food transfers, (ii) consistent with dyad-level data indicating kin and contingency biases in food transfers, and (iii) supported by the apparent lack of a production-consumption correlation across small-scale communities.
Coarse-Graining Hamiltonian Systems Using WSINDy
Authors: Messenger Daniel A. , Burby Joshua W. , Bortz David M. 
Published: December 2023

Abstract

The Weak-form Sparse Identification of Nonlinear Dynamics algorithm (WSINDy) has been demonstrated to offer coarse-graining capabilities in the context of interacting particle systems (https://doi.org/10.1016/j.physd.2022.133406). In this work we extend this capability to the problem of coarse-graining Hamiltonian dynamics which possess approximate symmetries associated with timescale separation. A smooth ε-dependent Hamiltonian vector field Xε possesses an approximate symmetry if the limiting vector field X0 = limε→0 Xε possesses an exact symmetry. Such approximate symmetries often lead to the existence of a Hamiltonian system of reduced dimension that may be used to efficiently capture the dynamics of the symmetry-invariant dependent variables. Deriving such reduced systems, or approximating them numerically, is an ongoing challenge. We demonstrate that WSINDy can successfully identify this reduced Hamiltonian system in the presence of large perturbations imparted in the ε > 0 regime, while remaining robust to extrinsic noise. This is significant in part due to the nontrivial means by which such systems are derived analytically. WSINDy naturally preserves the Hamiltonian structure by restricting to a trial basis of Hamiltonian vector fields. The methodology is computational efficient, often requiring only a single trajectory to learn the global reduced Hamiltonian, and avoiding forward solves in the learning process. In this way, we argue that weak-form equation learning is particularly well-suited for Hamiltonian coarse-graining. Using nearly-periodic Hamiltonian systems as a prototypical class of systems with approximate symmetries, we show that WSINDy robustly identifies the correct leading-order system, with dimension reduced by at least two, upon observation of the relevant degrees of freedom. We also provide a contribution to the literature on averaging theory by proving that first-order averaging at the level of vector fields preserves Hamiltonian structure in nearly-periodic Hamiltonian systems. We provide physically relevant examples, namely coupled oscillator dynamics, the Hénon-Heiles system for stellar motion within a galaxy, and the dynamics of charged particles.
Unraveling the adaptive mechanisms of Veronica nakaiana in response to drought stress: a transcriptome-based study
Authors: Kaur Chetan , Kwon Young Hyun , Song Ha Young , Gil Min , Rhie Yong Ha , Lee Geung-Joo 
Published: December 2023

Abstract

Drought is a severe environmental constraint to plant productivity. Being a multidimensional stress, it triggers a wide variety of plant responses at the physiological, biochemical, and molecular levels. Exploring stress-related genes in endemic plants such as Veronica nakaiana paves the way to identifying how these plants thrive in their respective locations. To identify genes related to the drought stress response in V. nakaiana, we compared the transcriptomes of plants under well-watered (WW) and drought-stressed (DS) conditions using RNA-sequencing. In DS plants, plant height, root length, leaf area, and stomatal width were significantly reduced, and stomatal density was increased. Interestingly, fresh, and dry weights did not significantly differ between WW and DS plants. To our knowledge, this was the first attempt to establish a de novo transcriptome-based sequence assembly of V. nakaiana under drought stress. We identified 2,261 upregulated and 3,315 downregulated differentially expressed genes in DS plants. In-depth data analysis revealed that a large number of these genes were associated with drought stress responses, including heat shock proteins, abiotic stress related transcription factors, and factors involved in abscisic acid signaling, lipid metabolism, and auxin binding. The results provide insights into the different mechanisms contributing to the drought response in V. nakaiana.
Two pathological patterns in different stages of the same disease：A case report
Authors: He Li , Wang Qiangtao , Liu Jing , Liu Yifan , Ma Jingping , Mao Jinghua 
Published: December 2023

Abstract

This case reports a patient with IgG4 related (IgG4-RD) lung disease who exhibited two different pathological manifestations during the disease process. IgG4 related diseases are a newly defined immune-mediated chronic inflammatory fibrosis disease in recent years. The most common clinical symptoms of this disease are a significant increase in serum IgG4 levels and a mass like lesion.IgG4 RD may have different pathological changes at different stages of the disease, mainly following two stages of development. Its characteristic is the "inflammation" stage, which ultimately leads to "fibrosis" results. Histopathology plays an extremely important role in disease diagnosis. Compared with imaging, it may detect the trend of pulmonary fibrosis earlier to better guide the diagnosis and treatment of IgG4 RD.