bluuebunny/crossref_metadata_2025_split huggingface dataset:
Randomized Trial of a Volunteer-Led Symptom Assessment Intervention on Documentation, Patient-Reported Outcomes, and Health Care Use Among Veterans With Lung Cancer
Authors: Banks LaKedia Charman , Kapphahn Kris , Das Millie , Patel Manali I. 
Published: January 2024

PURPOSE Identification and documentation of Veterans' symptoms are crucial for optimal lung cancer care delivery. The objective of this study was to determine whether a volunteer-led proactive telephone symptom assessment intervention could improve comprehensive symptom documentation. METHODS Veterans with lung cancer were randomly assigned to usual care (control group) or usual care with proactive symptom assessment in which a peer volunteer made weekly phone calls to assess patient symptoms under nurse practitioner supervision. The primary outcome was oncologist documentation of symptoms in the electronic health record at all clinical visits within 6 months after enrollment. Secondary outcomes included patient satisfaction with decision, patient activation, health-related quality of life (HRQOL), and symptom burden, measured at baseline, and 3, 6, and 9 months after enrollment, and acute care use within 9 months after enrollment. RESULTS Among 60 Veterans randomly assigned, median (range) age was 70.2 (50-86) years; 57 (95.0%) were male. More intervention participants had oncologist documentation of symptoms than control group participants (24 [77.4%] v seven [24.1%], respectively; odds ratio, 16.46 [95% CI, 4.58 to 59.16]). Intervention group participants had greater improvements over time in HRQOL (expected mean difference, 25.3 [95% CI, 15.00 to 35.70]) and patient activation (expected mean difference, 13.6 [95% CI, 3.79 to 23.39]), lower symptom burden (expected mean difference, –6.39 [95% CI, –15.21 to –2.46]), lower rates of emergency room visits (incidence rate ratio, 0.48 [95% CI, 0.30 to 0.75]), and hospitalizations (incidence rate ratio, 0.47 [95% CI, 0.28 to 0.77]) than control group participants. CONCLUSION This symptom assessment intervention is an effective strategy for Veterans with lung cancer.
Thyroiditis After Parathyroidectomy
Authors: Kwayess Rola , Cooper David S , Fuleihan Ghada El-Hajj 
Published: January 2024

Abstract
Various clinical manifestations of thyroiditis after parathyroidectomy have been reported in the literature, ranging from mild symptoms to tachyarrhythmias and myocardial infarction. We report 2 cases of post-parathyroidectomy thyroiditis. Both patients had primary hyperparathyroidism and underwent parathyroidectomy for a solitary parathyroid adenoma. They subsequently developed symptoms of hyperthyroidism, including palpitations and heat intolerance. Laboratory investigations demonstrated a suppressed TSH level with elevated free T4 levels and low uptake on thyroid radioiodine scan, confirming the diagnosis of thyroiditis. The patients were managed conservatively, and their symptoms gradually resolved with normalization of thyroid hormone levels. A review of 27 cases reported to date reveals that this condition is mostly attributed to manipulation of the thyroid during parathyroid surgery. It occurs more frequently in patients who undergo 4-gland parathyroidectomy for secondary or tertiary hyperthyroidism and is self-limited within a few weeks. The case reports highlight the importance of recognizing thyroiditis as a potentially underrecognized complication of parathyroid surgery. Further research is warranted to better understand the underlying pathophysiology and to establish potential risk factors for its development post-parathyroidectomy.
Control of successive unequal cell divisions by neural cell fate regulators determines embryonic neuroblast cell size
Authors: Mullan Thomas W. , Felton Terry , Tam Janis , Kasem Osama , Yeung Tim J. , Memar Nadin , Schnabel Ralf , Poole Richard J. 
Published: January 2024

ABSTRACT
Asymmetric cell divisions often generate daughter cells of unequal size in addition to different fates. In some contexts, daughter cell size asymmetry is thought to be a key input to specific binary cell fate decisions. An alternative possibility is that unequal division is a mechanism by which a variety of cells of different sizes are generated during embryonic development. We show here that two unequal cell divisions precede neuroblast formation in the C lineage of Caenorhabditis elegans. The equalisation of these divisions in a pig-1/MELK mutant background has little effect on neuroblast specification. Instead, we demonstrate that let-19/MDT13 is a regulator of the proneural basic helix-loop-helix transcription factor hlh-14/ASCL1 and find that both are required to concomitantly regulate the acquisition of neuroblast identity and neuroblast cell size. Thus, embryonic neuroblast cell size in this lineage is progressively regulated in parallel with identity by key neural cell fate regulators. We propose that key cell fate determinants have a previously unappreciated function in regulating unequal cleavage, and therefore cell size, of the progenitor cells whose daughter cell fates they then go on to specify.
Assembly, dynamics and remodeling of epithelial cell junctions throughout development
Authors: Mira-Osuna Marta , Borgne Roland Le 
Published: January 2024

ABSTRACT
Cell junctions play key roles in epithelial integrity. During development, when epithelia undergo extensive morphogenesis, these junctions must be remodeled in order to maintain mechanochemical barriers and ensure the cohesion of the tissue. In this Review, we present a comprehensive and integrated description of junctional remodeling mechanisms in epithelial cells during development, from embryonic to adult epithelia. We largely focus on Drosophila, as quantitative analyses in this organism have provided a detailed characterization of the molecular mechanisms governing cell topologies, and discuss the conservation of these mechanisms across metazoans. We consider how changes at the molecular level translate to tissue-scale irreversible deformations, exploring the composition and assembly of cellular interfaces to unveil how junctions are remodeled to preserve tissue homeostasis during cell division, intercalation, invagination, ingression and extrusion.
Mitochondrial function and sexual selection: can physiology resolve the ‘lek paradox’?
Authors: Crino Ondi L. , Head Megan L. , Jennions Michael D. , Noble Daniel W. A. 
Published: January 2024

ABSTRACT
Across many taxa, males use elaborate ornaments or complex displays to attract potential mates. Such sexually selected traits are thought to signal important aspects of male ‘quality’. Female mating preferences based on sexual traits are thought to have evolved because choosy females gain direct benefits that enhance their lifetime reproductive success (e.g. greater access to food) and/or indirect benefits because high-quality males contribute genes that increase offspring fitness. However, it is difficult to explain the persistence of female preferences when males only provide genetic benefits, because female preferences should erode the heritable genetic variation in fitness that sexually selected traits signal. This ‘paradox of the lek’ has puzzled evolutionary biologists for decades, and inspired many hypotheses to explain how heritable variation in sexually selected traits is maintained. Here, we discuss how factors that affect mitochondrial function can maintain variation in sexually selected traits despite strong female preferences. We discuss how mitochondrial function can influence the expression of sexually selected traits, and we describe empirical studies that link the expression of sexually selected traits to mitochondrial function. We explain how mothers can affect mitochondrial function in their offspring by (a) influencing their developmental environment through maternal effects and (b) choosing a mate to increase the compatibility of mitochondrial and nuclear genes (i.e. the ‘mitonuclear compatibility model of sexual selection’). Finally, we discuss how incorporating mitochondrial function into models of sexual selection might help to resolve the paradox of the lek, and we suggest avenues for future research.
Breast Cancer Risk Assessment among Rural Women in Turkey
Authors: Ardahan Melek , Topçu Sevcan 
Published: January 2024

Background: Breast cancer is the most prevalent cancer type in women both Turkey and worldwide. In order to construct screening programs correctly, to identify breast cancer at the early stage and to reduce the burden of disease after diagnosis; first, women’s risk levels should be determined.
Aim: The aim of this study is to identify women’s breast cancer risk levels, the frequency of BSE, and affecting factors in rural women in Turkey.
Method and Material: This cross-sectional study was included 280 adult women. As data collection tools were used “The Sociodemographic Characteristics Questionnaire” and “Breast Cancer Risk Assessment Tool”.
Results: Women’s mean breast cancer risk level was found as 137.69±67.56. 91.1 % of women were found to be in a low-risk group. When women’s mean scores related to Breast Cancer Risk Assessment Tool and sociodemographic variables were compared and a statistically significant difference was detected between vocational status, education level and smoking status. The vast majority of women take place in the low-risk group in terms of breast cancer.
Conclusions: The effects of community-based and opportunistic national breast cancer screenings on mortality rates and their cost-effectiveness must be assessed. Primarily, individual breast cancer risk evaluations must be done instead of community-based screenings, useful tools must be selected for risk evaluation, screening programs must be performed according to the risk and women should be invited to health organizations for screenings.
Noisebnb: An Empirical Analysis of Home-Sharing Platforms and Residential Noise Complaints
Authors: Ozer Gorkem Turgut , Greenwood Brad N. , Gopal Anandasivam 
Published: January 2024

Practice and Policy-Based Abstract Externalities stemming from digital platforms have had a profound impact on the daily lives of people across the globe. In this work, we examine one such externality that contributes to urban quality of life, the noise stemming from home-sharing platforms, which has been subject to aggressive scrutiny by policymakers and the popular press but has received limited rigorous empirical attention. Against a backdrop of significant investment by municipalities to curb extant levels of urban noise, our findings suggest that these platforms are instead correlated with a decrease in noise complaints in New York City (notably when occupancy rates are lower or the residence is located near tourist attractions). These findings suggest that investments in abating the noise stemming from such short-term rentals are less necessary than indicated by anecdotal evidence and are better directed at other forms of urban noise sources, chiefly because such rental units are frequently unoccupied and therefore remain quieter than residential units. However, these findings also underscore the extent to which home-sharing networks may be further straining the already stressed housing market in large metropolitan areas like New York City.
Multi-band terahertz metamaterial absorber composed of concentric square patch and ring resonator array
Authors: Asgari Somayyeh , Fabritius Tapio 
Published: January 2024

An equivalent circuit model (ECM) to analyze a single-layered graphene multi-band metamaterial absorber was developed. This absorber consists of concentric square patch and ring resonator arrays and operates in the terahertz (THz) region. To validate our analysis based on the ECM, we also conducted numerical simulations using the finite element method (FEM) within CST software. Additionally, we have explained the absorption behavior of the metamaterial using the coupled mode theory (CMT). This absorber design, with its single-layer structure, tunability, and triple absorption bands, offers promise for applications in THz devices and systems. Notably, it achieves an average absorption of 99% for three bands and the absorption reaches 100% in the frequency range of 4 to 6.5 THz. The correlation of ECM and CMT analyses with the FEM simulations validate the accuracy and the effectiveness of these simplified approaches in comprehending the resonant characteristics of the metamaterial absorber.
Electromyographic biofeedback therapy for improving limb function after stroke: A systematic review and meta-analysis
Authors: Wang Rui , Zhang Shuangshuang , Zhang Jie , Tong Qifeng , Ye Xiangming , Wang Kai , Li Juebao 
Published: January 2024

Background
Upper and lower limb impairment is common after stroke. Electromyographic biofeedback therapy is a non-invasive treatment, and its effectiveness in functional rehabilitation of the limb after stroke still remains uncertain.

Objective
The objective of this study was to evaluate whether electromyographic biofeedback can improve upper and lower limb dysfunction in stroke patients.

Methods
PubMed, Embase, Cochrane Library, and Physiotherapy Evidence Database (PEDro) were searched from inception to 1st May 2022. Inclusion criteria were randomized controlled clinical trials of electromyographic biofeedback therapy interventions reporting changes in upper and lower limb function in post-stroke patients. Data were extracted by two independent reviewers and pooled in random-effects models using Review manager (RevMan) software.

Results
Our analyses included 10 studies enrolling a total of 303 participants. Electromyographic biofeedback therapy can effectively improve limb function after stroke (standardized mean difference [SMD], 0.44; 95% confidence interval [CI], 0.12–0.77; P = 0.008) and in subgroup analyses, the effect sizes of short-term effect (SMD, 0.33; 95% CI, 0.02–0.64; P = 0.04) was significant, but the long-term was not (SMD, 0.61; 95% CI, -0.11–1.33; P = 0.10). In addition, Electromyographic biofeedback therapy can improve the active range of motion of shoulder (SMD, 1.49; 95% CI, 2.22; P<0.0001) and wrist joints (SMD, 0.77; 95% CI, 0.13–1.42; P = 0.02) after stroke.

Conclusion
In this meta-analysis, electromyographic biofeedback therapy intervention can improve upper and lower limb function in patients with stroke. Short-term (less than one month) improvement after electromyographic biofeedback therapy was supported, while evidence for long-term (more than one month) benefits was lacking. Range of motion in the glenohumeral and wrist joints were improved. Stronger evidence for individualized parameters, such as optimal treatment parameters and intervention period, is needed in the future.

Systematic review registration
[https://www.crd.york.ac.uk/prospero/display_record.php?recordID=267596], identifier [CRD42022354363].
Association between abdominal adiposity and clinical outcomes in patients with acute ischemic stroke
Authors: Wakisaka Kayo , Matsuo Ryu , Irie Fumi , Wakisaka Yoshinobu , Ago Tetsuro , Kamouchi Masahiro , Kitazono Takanari ,   on behalf of the Fukuoka Stroke Registry Investigators
Published: January 2024

Background
It is unclear whether abdominal adiposity has an additional effect on post-stroke outcomes. This study aimed to determine whether waist circumference (WC) is independently associated with clinical outcomes after acute ischemic stroke.

Methods
We enrolled patients with acute ischemic stroke from a multicenter hospital-based stroke registry in Fukuoka, Japan. We measured WC on admission and categorized patients into four groups (Q1–Q4) according to the quartiles in females and males. The clinical outcomes were poor functional outcome (modified Rankin scale score 2–6) and death from any cause. Logistic regression analysis was performed to estimate the odds ratio and 95% confidence interval of the outcomes of interest after adjusting for potential confounding factors, including body mass index (BMI).

Results
A total of 11,989 patients (70.3±12.2 years, females: 36.1%) were included in the analysis. The risk of poor functional outcome significantly decreased for Q2–Q4 (vs. Q1) at discharge and Q2–Q3 (vs. Q1) at 3 months, even after adjusting for potential confounders, including BMI. In contrast, adjustment of BMI eliminated the significant association between WC and all-cause death at discharge and 3 months. The association between high WC and favorable functional outcome was not affected by fasting insulin levels or homeostatic model assessment for insulin resistance and was only found in patients without diabetes (P = 0.02 for heterogeneity).

Conclusions
These findings suggest that abdominal adiposity has an additional impact on post-stroke functional outcome, independent of body weight and insulin action.
Sex differences in growth and mortality in pregnancy-associated hypertension
Authors: Hercus Jess C. , Metcalfe Katherine X. , Christians Julian K. 
Published: January 2024

Background
It is hypothesized that male fetuses prioritize growth, resulting in increased mortality, whereas females reduce growth in the presence of adversity. Preeclampsia reflects a chronic condition, in which fetuses have the opportunity to adjust growth. If females reduce their growth in response to preeclampsia, but males attempt to maintain growth at the cost of survival, we predict that differences in birthweight between preeclamptic and non-preeclamptic pregnancies will be greater among females, whereas differences in mortality will be greater among males.

Methods
We analysed data from the Centers for Disease Control and Prevention. We compared pregnancies with pregnancy-associated hypertension (PAH) and controls.

Results
The difference in birthweight between pregnancies affected by PAH and controls varied by fetal sex and gestational age. Among pregnancies of White individuals, at 34–35 weeks, the difference between PAH and controls was higher among females, as predicted. However, this pattern was reversed earlier in pregnancy and around term. Such variation was not significant in Black pregnancies. In both Black and White pregnancies, early in gestation, males had lower odds of death in PAH pregnancies, but higher odds of death in control pregnancies, counter to our prediction. Later, males had higher odds of death in PAH and controls, although the increased odds of death in males was not higher in PAH pregnancies than in controls. Overall, the difference in birthweight between surviving and non-surviving infants was greater in males than in females, opposite to our prediction.

Conclusions
The impact of PAH on birthweight and survival varies widely throughout gestation. Differences in birthweight and survival between male and female PAH and controls are generally not consistent with the hypothesis that males prioritize fetal growth more than females, and that this is a cause of increased mortality in males.
SOCIO-ECONOMIC DIMENSIONS OF THE AL-IDRISIYAH TAREKAT IN INDONESIA: DOCTRINE AND PRACTICE
Authors: Mursalat Mursalat , Munandar Siswoyo Aris 
Published: January 2024

Tarekat or Sufi order is identical to various spiritual activities, often considered far from worldly life. This identification places Sufism as merely related to mystical and ascetic activities. This study intends to explain how the Al-Idrisiyah tarekat in Indonesia has primary concern on social and economic dimensions in all of their various empowerment programs in the community. The research uses qualitative methods, with data collection techniques of observation and documentation of tarekat activities on mixed social media. The study results show that the practice of the socio-economic dimension is an implementation of their belief that a true Sufi is a Sufi who works and empowers others. Their socio-economic activities have developed to resemble philanthropic activities and can help several community groups affected by the pandemic in 2020-2021.Tarekat atau sufi sering diidentikkan dengan kegiatan spiritual, yang dianggap menjauhi kehidupan duniawi. Identifikasi tersebut menyebabkan tasawuf dianggap dekat dengan hal-hal yang bersifat kebatinan dan asketik. Penelitian ini bermaksud untuk menjelaskan bagaimana Tarekat Al-Idrisiyah di Indonesia memiliki dimensi sosial dan ekonomi yang diterapkan dalam berbagai program pemberdayaan mereka di masyarakat. Penelitian dilakukan dengan menggunakan metode kualitatif dengan teknik pengumpulan data berupa observasi dan dokumentasi kegiatan-kegiatan tarekat di berbagai sosial media. Hasil penelitian menunjukkan bahwa praktik dimensi sosial-ekonomi tersebut merupakan implementasi dari keyakinan mereka bahwa seorang sufi yang benar adalah sufi yang bekerja dan memberdayakan manusia lainnya yang lemah. Kegiatan sosial-ekonomi mereka tersebut berkembang menyerupaikan aktivitas filantropi dan mampu membantu beberapa kelompok masyarakat yang terdampak pandemi di tahun 2020-2021.
LEARNING ISLAM IN A MODERATE WAY: HOW PESANTREN TEACHES ISLAMIC VALUES AND NATIONHOOD TOWARD SANTRI?
Authors: Suprapto Suprapto 
Published: January 2024

The 9/11 tragedy has brought up negative stereotype to pesantren identified as a radical Islamic educational institution in Indonesia. In April 2022, BNPT (National Counterterrorism Agency) released 198 Islamic boarding schools which affiliated with radicalism. The increasing cases of intolerant acts in Indonesia have been exacerbating the relations among religious communities. This study intends to analyze the roles of two Islamic boarding schools, that are Al-Hikmah and Roudhotut Tholibin, in Indonesia, in producing moderate values of Islam to their students. This study employs a qualitative approach through a case study. Data were collected by observing various activities in the two Islamic boarding schools, FGD, and in-depth interviews with ten informants. The findings showed that Pesantren Al-Hikmah and Pesantren Roudhotut Tholibin taught moderate values of Islam, primarily through the teaching process of the classical book entitled Idhotun Nasyi'in. It provides students with social aspects of interaction with non-Muslims and the values of differences. In doing so, students are also invited to participate in community activities to exercise the values of nationalism in Islamic boarding schools. This research further indicates that pesantren is not a place where radicalism grows but it has become an Islamic educational institution that can produce moderation and national values.Peristiwa terorisme 9/11 silam telah menyisakan stereotype negatif pada pesantren sebagai lembaga pendidikan Islam yang radikal di Indonesia. Pada April 2022 lalu, BNPT (Badan Nasional Penanggulangan Terorisme) telah merilis 198 pesantren yang terafiliasi dengan radikalisme. Hal ini diperburuk oleh data kasus intoleransi di Indonesia yang meningkat. Penelitian ini bermaksud untuk menganalisis dua pesantren yakni Al Hikmah dan Roudhotut Tholibin di Indonesia dalam peranannya memproduksi nilai-nilai moderat dalam berislam kepada para santri. Penelitian dilakukan dengan pendekatan kualitatif melalui studi kasus. Data dikumpulkan melalui observasi berbagai kegiatan di dua pesantren tersebut, FGD, dan wawancara mendalam terhadap 10 informan santri. Hasil penelitian menunjukkan bahwa Pesantren Al Hikmah dan Pesanten Roudhotut Tholibin justru mengajarkan nilai-nilai moderat dalam berislam, khususnya melalui pengajaran kitab klasik Idhotun Nasyi’in. Kitab-kitab beserta dengan tafsir yang diajarkan kepada santri sarat dengan ajaran-ajakan bagaimana berinteraksi secara baik dengan non-muslim dan kelompok yang berbeda. Santri juga diajak berpartisipasi dalam kegiatan di masyarakat sehingga mampu menumbuhkan benih-benih nasionalisme di pesantren. Penelitian ini selanjutnya menajdi indikasi kuat bahwa pesantren bukanlah tempat tumbuhnya radikalisme, namun justru telah menjadi lembaga pendidikan Islam yang mampu memproduksi nilai moderat dan nilai kebangsaan.