bluuebunny/crossref_metadata_2025_split huggingface dataset:
A scoping review of interventions and outcome measures in trials of dental behavior support
Authors: Mac Giolla Phadraig Caoimhin , Ahmad Fisal Aisyah Binti , Bird James , Kammer Pedro Vitali , Fleischmann Isabel , Geddis‐Regan Andrew 
Published: December 2023

AbstractBackgroundDental behavior support (DBS) describes all techniques used by dental professionals to ensure that dental care is safe, effective, and acceptable. There is a need to standardize outcome measures across DBS techniques to reduce heterogeneity, limit selective reporting, promote consistency, and optimize outcomes across DBS research. A comprehensive review of existing measures is a prerequisite to understanding potential outcomes related to the area of interest.AimThis review had three aims: first, to identify the outcome measures (OMs) reported in trials of dental behavior support; second, to categorize the component DBS techniques reported within interventions according to emerging agreed terminology; and, third, to map outcome measures to intervention type.MethodsA scoping review of trials evaluating DBS techniques was undertaken from 2012 to 2022. The review was prospectively registered. Studies were identified through Medline, Embase, and PsycINFO. Study abstracts were screened by two reviewers. Data were extracted by single selector. Outcome measures were sorted according to measurement domains (physiological, behavioral, psychological, and treatment). Responses were assimilated and summed to produce a refined list of distinguishable outcome measures. Intervention types were categorized according to accepted descriptors. Frequencies were presented; associations between outcome domain and DBS type were also reported (Chi‐square test of independence).ResultsA total of 344 trials were included in the review from an initial 14,793 titles / title and abstracts screened. Most involved children (n = 215), most were from India (n = 104), involving basic dental care (n = 117). The median number of outcome measures per trial was four (range = 1–12); 1,317 individual outcomes were reported, categorized as: psychological (n = 501, 38.0%); physiological (n = 491, 37.3%), behavioral (n = 123, 9.3%) or, treatment‐related (n = 202, 15.3%). DBS interventions were split between 239 (45.7%) pharmacological and 283 (54.1%) non‐pharmacological; 96.6% of interventions mapped to accepted descriptors. A significant relationship was noted between the type of intervention and the outcome domain reported.ConclusionThe findings demonstrate massive variation in outcome measures of DBS interventions that likely lead to unnecessary heterogeneity, selective reporting, and questionable relevance in the literature. A large range of DBS interventions were mapped according to BeSiDe list. There is a need for consensus on a core outcome set across the spectrum of DBS techniques.
Earnings, labor market dynamics, and inequality in Sweden
Authors: Holmberg Johan 
Published: December 2023

AbstractIn this paper, we develop a comprehensive model of earnings and labor market dynamics, where employment and job change are endogenous. The model is estimated by applying the method of indirect inference on Swedish register data, and then used to carry out some policy experiments. There are three key conclusions from these experiments. First, employment shocks early in life can, to a larger extent, be mitigated before retirement compared with employment shocks occurring later. Second, we find that idiosyncratic productivity shocks, unobserved heterogeneity, and education contribute substantially to life‐cycle earnings inequality. Finally, we find that transitory shocks to employment risk have negative effects on earnings and employment in the short run but may increase labor market fluidity in the medium run.
Assessment of potential soil erosion in Mongolia based on the RUSLE model and RCP 8.5 scenario
Authors: Tuvshinjargal Namuun , Lamchin Munkhnasan , Kim Yoonji , Bayarmagnai Enerel , Jeon Seong Woo 
Published: December 2023

AbstractDue to its relatively high altitude and a continental climate, environmental issues related to soil erosion and land degradation more seriously affect the ecosystem and crop production in Mongolia. As detailed soil erosion and land degradation assessments have only been performed in some regions of Mongolia, the purpose of this study is to evaluate the soil vulnerability on a national scale and predict future soil erosion under climate change prior to establishing an appropriate management plan. The revised universal soil loss equation model was chosen for this study, which reflects geographic and climatic characteristics in a vast area as the Mongolian territory. We evaluated soil erosion using historical data from 1993 and 2013 and generated predictions in the near (2041–2060) and far future (2061–2080) periods under the representative concentration pathway 8.5 scenario. The soil erosion rates were divided into six classes: very low, low, medium, high, very high and extreme. The total of 46,039 km2 of the Mongolian territory was classified as very high and extreme risk, which is predicted to increase up to 48,961 and 51,769 km2, in the near and far future periods, respectively. At the national scale, most of the soil erosion appeared in bare area, as it covers more than 60% of the total area. Meanwhile, the highest soil erosion risk was expected in high mountain ranges and ecologically vulnerable regions of the Gobi Desert and steppe area. This study identifies three land cover types with high priority for management and areas that should be considered first in the sustainable national land use and soil management plans considering regional characteristics.
A low thrombospondin‐1 serum concentration is related to increased bacteremia risk in lymphoma patients treated with BeEAM/BEAM conditioning regimen and autologous stem cell transplantation
Authors: Kościelny Kacper , Mikulski Damian , Nowicki Mateusz , Wyka Krystyna , Misiewicz Małgorzata , Perdas Ewelina , Wierzbowska Agnieszka , Fendler Wojciech 
Published: December 2023

Infectious complications of autologous hematopoietic stem cell transplantation (AHSCT) are the most common adverse effects of the therapy, resulting in prolonged hospitalization and deterioration of patient well‐being. Identifying predictors of these complications is essential for improving patient outcomes and guiding clinical management. This study aimed to examine thrombospondin‐1 (THBS‐1) serum levels as a potential biomarker for predicting bacteremia in AHSCT recipients. Blood samples were collected from 30 patients undergoing BeEAM/BEAM (bendamustine/carmustine, etoposide, cytarabine, melphalan) conditioning regimen at subsequent time points during AHSCT. THBS‐1 levels were quantified using ELISA kits. Patients who developed bacteremia (n = 11) during the AHSCT course had lower THBS‐1 concentration compared with those without (n = 19) (22.88 ± 11.53 µg/mL vs. 15.24 ± 5.62 µg/mL, p = .0325). The ROC curve analysis revealed that THBS‐1 serum concentration at the first day of BeEAM/BEAM regimen had an area under the curve of 0.732 (95%CI: 0.5390.925, p = .0186) with an optimal cut‐off value of 16.5 µg/ml resulting in 82% Sensitivity and 53% Specificity for predicting bacteremia with a median of 11 days before its occurrence. Patients with lower THBS‐1 concentrations experienced febrile neutropenia significantly earlier, with a median difference of 5 days (p = .0037). Patients with a low concentration of THBS‐1 had a higher risk of bacteremia and a shorter time to febrile neutropenia, indicating its potential value as a complications biomarker. Patients with lower serum THBS‐1 concentrations, indicating an increased risk, may be more suitable for an inpatient AHSCT procedure, where close monitoring and immediate intervention are accessible.
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Haplotypes at the sorghum ARG4 and ARG5 NLR loci confer resistance to anthracnose
Authors: Habte Nida , Girma Gezahegn , Xu Xiaochen , Liao Chao‐Jan , Adeyanju Adedayo , Hailemariam Sara , Lee Sanghun , Okoye Pascal , Ejeta Gebisa , Mengiste Tesfaye 
Published: December 2023

SUMMARYSorghum anthracnose caused by the fungus Colletotrichum sublineola (Cs) is a damaging disease of the crop. Here, we describe the identification of ANTHRACNOSE RESISTANCE GENES (ARG4 and ARG5) encoding canonical nucleotide‐binding leucine‐rich repeat (NLR) receptors. ARG4 and ARG5 are dominant resistance genes identified in the sorghum lines SAP135 and P9830, respectively, that show broad‐spectrum resistance to Cs. Independent genetic studies using populations generated by crossing SAP135 and P9830 with TAM428, fine mapping using molecular markers, comparative genomics and gene expression studies determined that ARG4 and ARG5 are resistance genes against Cs strains. Interestingly, ARG4 and ARG5 are both located within clusters of duplicate NLR genes at linked loci separated by ~1 Mb genomic region. SAP135 and P9830 each carry only one of the ARG genes while having the recessive allele at the second locus. Only two copies of the ARG5 candidate genes were present in the resistant P9830 line while five non‐functional copies were identified in the susceptible line. The resistant parents and their recombinant inbred lines carrying either ARG4 or ARG5 are resistant to strains Csgl1 and Csgrg suggesting that these genes have overlapping specificities. The role of ARG4 and ARG5 in resistance was validated through sorghum lines carrying independent recessive alleles that show increased susceptibility. ARG4 and ARG5 are located within complex loci displaying interesting haplotype structures and copy number variation that may have resulted from duplication. Overall, the identification of anthracnose resistance genes with unique haplotype stucture provides a foundation for genetic studies and resistance breeding.
The Arabidopsis tDR Ala forms G‐quadruplex structures that can be unwound by the DExH1 DEA(D/H)‐box RNA helicase
Authors: Chery Marjorie , Berrissou Christina , Humbert Nicolas , Hummel Guillaume , Mely Yves , Salinas‐Giegé Thalia , Drouard Laurence 
Published: December 2023

SUMMARYAs in many other organisms, tRNA‐derived RNAs (tDRs) exist in plants and likely have multiple functions. We previously showed that tDRs are present in Arabidopsis under normal growth conditions, and that the ones originating from alanine tRNAs are the most abundant in leaves. We also showed that tDRs Ala of 20 nt produced from mature tRNAAla (AGC) can block in vitro protein translation. Here, we report that first, these tDRs Ala (AGC) can be found within peculiar foci in the cell that are neither P‐bodies nor stress granules and, second, that they assemble into intermolecular RNA G‐quadruplex (rG4) structures. Such tDR Ala rG4 structures can specifically interact with an Arabidopsis DEA(D/H) RNA helicase, the DExH1 protein, and unwind them. The rG4‐DExH1 protein interaction relies on a glycine‐arginine domain with RGG/RG/GR/GRR motifs present at the N‐terminal extremity of the protein. Mutations on the four guanine residues located at the 5′ extremity of the tDR Ala abolish its rG4 structure assembly, association with the DExH1 protein, and foci formation, but they do not prevent protein translation inhibition in vitro. Our data suggest that the sequestration of tDRs Ala into rG4 complexes might represent a way to modulate accessible and functional tDRs for translation inhibition within the plant cell via the activity of a specific RNA helicase, DExH1.
Diagnostic imaging descriptions and prevalence of presumed phrenic lymph nodes in dogs
Authors: Cordella Alessia , Stock Emmelie , Cornillie Pieter , Fouriez‐Lablée Virginie , Skarbek Adrianna , Germonpré Jolien , Saunders Jimmy 
Published: December 2023

AbstractThe phrenic lymph node (PLN) has been described in bovine, equine, and feline anatomic references but descriptions in canine anatomic references are currently lacking. Authors have observed a well‐defined, soft tissue attenuating, contrast‐enhancing structure in a location consistent with previous anatomic descriptions of the PLN in dogs that underwent thoracic CT for neoplastic staging. The aims of this two‐part, retrospective/prospective, anatomic, prevalence study were (1) to describe the presence of a soft tissue structure close to the thoracic caudal vena cava, defined as the presumed PLN, in a series of dogs that underwent CT as part of the staging for metastatic disease; (2) to confirm the lymphatic origin of the presumed PLN in a dog through postmortem examination; (3) to assess the prevalence of the presumed PLN in a population of dogs that underwent thoracic CT or MRI for different clinical purposes; and (4) to assess the possibility to visualize the presumed PLN with ultrasonography. The lymphatic origin of the presumed PLN was confirmed by postmortem examination in one dog. The presumed PLN was visible in 29 of 777 canine CT examinations (prevalence 3.7%). The presumed PLN was not visible in 9 of 10 prospectively recruited ultrasound cases. Most dogs with visible presumed PLNs were large‐medium breeds that were presented for neoplastic staging purposes. Findings indicated that a structure consistent with the previously reported anatomic features of PLN in cattle, horses, and cats may be detected with a low prevalence in canine CT and MRI examinations.
Potential for emergence of Japanese encephalitis in the European Union
Authors: Gossner Céline M. , Dhollander Sofie , Presser Lance D. , Briet Oliver , Bakonyi Tamas , Schaffner Francis , Figuerola Jordi 
Published: December 2023

AbstractBackground and objectiveNo autochthonous human cases of Japanese encephalitis (JE) have been reported to date in the European Union (EU). In this study, we assess the likelihood of Japanese encephalitis virus (JEV) introduction and transmission within the EU and propose outbreak response measures.Risk assessmentGiven the global geographical distribution of JEV, the probability of virus introduction into the EU is currently very low, with viremic bird migration being the most plausible pathway of introduction. However, this likelihood would significantly increase if the virus were to become established in the Middle East, Caucasus, Central Asia or Africa. Considering the environmental conditions that are expected to be conducive for virus circulation, there is a high likelihood of virus transmission within the EU after its introduction in environmentally suitable areas. The spread of the virus within the EU would likely occur through the movement of wild birds, pigs and mosquitoes.MitigationTo mitigate or potentially contain the emergence of JE in the EU, early detection of both human and animal cases will be crucial.
PRELIMINARY STUDY OF AMBIENT ELECTROMAGNETIC RADIATION AT BASE TOWER STATIONS IN RESIDENTIAL AREAS IN KUALA NERUS
Authors: Senafi Nur Masuriawati , Abdullah Nazifah , Umar Roslan , Mohamed Nurul Syazwina , Tukimin Roha , Nik Wan Nik Ahmad Firdaus 
Published: December 2023

Introduction: Mobile communications developed into an integral component of our daily life. The growing demand for mobile communication services in Kuala Nerus has seen an increase in the installation of base station towers (BST) in residential areas, as well as near schools, and hospitals. Kuala Nerus was selected as a study location because it is a newly developed district in Terengganu, hence, it is crucial to perform electromagnetic radiation (EMR) measurements in the early stages. Objective/aim: This study aimed to measure the RF EMR exposure level in residential areas in Kuala Nerus by measuring the strength of its electric field (EF) strength and power density (PD) value while comparing it with the ICNIRP’s standard guidelines. Materials and methods: Measurements were made using NARDA NBM 550, connected to a probe that could detect frequencies from 100kHz to 6GHz. The data collection period for each point was approximately 6 minutes during daytime. Results: Average radiation levels in terms of EF strength at all locations were found to vary between 0.26 (V/m) to 3.35 (V/m) (PD value about 0.02 µW/cm² to 2.97 µW/cm²). The highest level was measured at Surau Kg Pok Tuyu, which was 5.48% or 18 times lower than the MCMC exposure limit for public areas. Conclusion: The RF value obtained does not exceed the standard limit, which in turn contributes indirectly to health monitoring initiatives for public NIR exposure. This study found that exposure levels in selected BSTs in residential areas in Kuala Nerus were within the standard guideline limits.
Complete genome sequence of
Pseudomonas
phage Ep4 lysing the kiwifruit canker bacteria
Authors: Aono Mitsuo , Yagi Haruka , Kobayashi Kappei 
Published: December 2023

ABSTRACT

Pseudomonas syringae
pv.
actinidiae
is a pathogen of kiwifruit canker. Ep4, a bacteriophage lysing the pathogenic bacteria, was isolated from an affected plant. Sequencing and annotation have revealed 44,614-bp genome with 52 predicted open reading frames. Ep4 is closest to
Pseudomonas
phage YMC11/06/C171_PPU_BP, albeit with low homology.
An experimental investigation of the characteristics of cataclastic bands in high-porosity sandstones
Authors: Jiang Mingming , Fu Xiaofei , Wang Zicheng 
Published: December 2023

Abstract
Cataclastic bands in high-porosity sandstones significantly influence fluid flow, thus impacting the exploration and development of oil and gas. However, little experimental research has been conducted on the main factors controlling the formation, evolution, and physical properties of cataclastic bands. Moreover, it is difficult to use field surveys to discern variations and trends in the structural and physical properties of cataclastic bands formed during different deformation processes. In this study, we used a high-pressure and low-velocity ring-shear apparatus to analyze high-porosity, pure sandstone. Multiple sets of ring-shear experiments were carried out using the effective normal stress or shear displacement as a single variable. The experimental samples were analyzed based on physical property tests and thin sections. Our results indicate that the particles in the cataclastic bands generally have better roundness and are smaller (by at least two to three orders of magnitude) than the host rock. The porosity and permeability of the cataclastic bands are ~70% lower and two to three orders of magnitude lower than those of the host rock, respectively. The characteristics of the cataclastic bands are controlled by two main factors, namely, the effective normal stress and shear displacement. The effective normal stress controls the intensity of the cataclasis, and the shear displacement controls the physical properties of the grains and indirectly controls the evolutionary stage, which corresponds to the intensity of cataclasis. As the effective normal stress or shear displacement increases, the cataclasis in the cataclastic bands intensifies, and the grain size decreases; then, the decrease in the porosity gradually declines, and the permeability decrease and thickness increase and then plateau. The results of this study reveal the evolutionary mechanisms of the structural and physical properties of cataclastic bands in high-porosity sandstones and lay a theoretical foundation for determining the effect of these bands on fluid flow in oil and gas reservoirs.
Mediterranean diet adherence and nutritional literacy: an observational cross-sectional study of the reality of university students in a COVID-19 pandemic context
Authors: Abreu Filipa , Hernando Ana , Goulão Luís Filipe , Pinto Alexandra Marques , Branco Amélia , Cerqueira Ana , Galvão Cecília , Guedes Fábio Botelho , Bronze Maria Rosário , Viegas Wanda , de Matos Margarida Gaspar , Sousa Joana 
Published: December 2023

AimTo evaluate the adherence to the Mediterranean diet (MD) and the level of nutritional literacy (NL) among university students from different academic fields of study, within the context of the COVID-19 pandemic.MethodsA total of 1114 first-year undergraduate students at the University of Lisbon, Portugal, were included in this study. A self-administered online questionnaire was applied that included questions regarding sociodemographic information, the MD measured by the PREDIMED questionnaire (PREvención con DIeta MEDiterránea) and NL assessed using the Newest Vital Sign questionnaire.ResultsThe average PREDIMED score revealed a low adherence (6.79±2.14 points) to the MD. Notably, students in the Social Sciences and Humanities academic fields showed the highest level of adherence (U=21 071; p<0.05). Within the Health field, there was a greater prevalence of dietary behaviours aligned with the MD, contributing to higher overall adherence scores. Furthermore, 84.1% of the participants demonstrated adequate NL. Interestingly, students in the Exact Sciences and Engineering field demonstrated the highest levels of NL (5.07±1.19), particularly in questions involving mathematical reasoning.ConclusionsOur findings suggest that university students in Lisbon do not follow a MD and are far from the recommendations of this dietary pattern. While most participants showed adequate NL, it is essential to highlight the link between knowledge and application to daily practice. Despite positive literacy levels, there remains a deficit in translating this knowledge into correct dietary practices.
‘Godrevy Project’: virtual reality for symptom control and well-being in oncology and palliative care – a non-randomised pre-post interventional trial
Authors: Moon Niall O , Henstridge-Blows Jemima R , Sprecher Eva A , Thomas Elizabeth , Byfield Amy , McGrane John 
Published: December 2023

ObjectiveThe ‘Godrevy Project’ is an interventional trial designed to determine the effectiveness of immersive virtual reality (VR) on the holistic symptom control and well-being in oncology and palliative care patients. The primary objective of this study was to determine whether VR changed the revised Edmonton Symptom and Assessment System (ESAS-r) score representing an effective improvement in symptom control and well-being.Methods and analysisThis study reports on 60 participants recruited from hospital inpatient oncology and palliative care lists, to participate in an unblinded, VR intervention. Participants were included aged >18 years with a diagnosis of cancer, receiving inpatient treatment of systemic anticancer therapy. Impact evaluation on symptoms was measured using the ESAS-r pre-VR and post-VR intervention. For ethical reasons, participants were not randomised.ResultsFrom the 60 inpatients recruited, 58 participants were included for analysis. Participants recruited were aged 19–84 years with female (58%) and male (42%) participation. The primary outcome of the study demonstrated significant improvement in ESAS-r scores for symptoms and well-being. Total ESAS-r scores showed an improvement of 42% compared with baseline, with well-being ESAS-r scores improving 51%. The most common side effect was drowsiness. There were no adverse events related to study participation.ConclusionThe ‘Godrevy Project’ successfully demonstrates the feasible, effective use of VR on symptom control and well-being in oncology and palliative care patients. This study demonstrates VR as an effective, patient controlled, non-pharmacological intervention without significant side effects. This interventional trial is well placed to support future research and improve clinical practice.Trial registration numberNCT04821466.