bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stochastic inactivation evaluation of foodborne pathogens during ohmic heating of poultry meat
Authors: Turgut Sebahattin Serhat , Feyissa Aberham Hailu 
Published: November 2023

Abstract
The objective of this study is to stochastically assess the inactivation probabilities of four common foodborne pathogens (Listeria, Salmonella, Escherichia coli, and Campylobacter) in chicken meat during ohmic heating (OH) in a salt solution. A mechanistic model was used to accomplish this, coupling heat transfer, laminar fluid flow, and the electric field, and solved numerically using COMSOL Multiphysics® v5.6. The 3D model represented 1000 particles randomly placed on the meat’s surface to determine the 7-log reduction of bacterial load probability. These particles are virtual representatives of bacterial colonies in the model. The influence of uncertain input parameters (specific heat capacity and electrical conductivity) and OH conditions (salt concentration of the heating medium, applied voltage, and heating time) was explained using logistic regression. The same analysis was repeated for the slowest heating point of chicken meat, as well. According to the findings, cold spots are observed at the corners of the meat piece during OH, requiring additional attention to the meat surface temperature to prevent under-processing. Sensitivity analysis revealed that the applied voltage and brine concentration are the main factors affecting the inactivation probabilities of pathogenic bacterial cells on the chicken meat surface. Salmonella and Listeria may require higher electrical conductivity of chicken meat and longer processing times. The developed model enables predicting inactivation probabilities of microorganisms that can be found on the outer surface by measuring the core temperature of the meat. However, especially for bacteria with higher heat resistance, it is better to consider the cold spot temperature found in the corners of the food material during OH.
Study on deformation characteristics of multi-pass continuous drawing of micro copper wire based on crystal plasticity finite element method
Authors: Wu Hanjiang , Huang Tao , Song Kexing , Zhang Yanmin , Zhou Yanjun , Li Shaolin , Li Xin 
Published: November 2023

Abstract
Copper-based wire has excellent comprehensive performance and is widely used in integrated circuit packaging, electronic communication, connectors, audio and video transmission, and other fields. Based on the crystal plasticity finite element method, the crystal plasticity finite element model of multi-pass continuous drawing deformation of pure copper micro wires was established, and the reliability of the model was proved. The continuous drawing deformation behavior of micro wires under high-speed deformation and micro wire diameter scale effect was studied. The research shows that there is a fracture risk zone under the alternating action of positive and negative stress values in the deformation zone of the drawn wire. The changing drawing force and contact stress during the continuous drawing process of the wire will also reduce the stability and surface quality of the wire during the drawing process. The shear deformation and slip degree of the surface grain of the drawn wire are greater than those of the core grain, and the drawing die has a greater impact on the slip system state of the surface of the wire. With the increase in drawing passes, the mechanical characteristics inside the wire increase accordingly, and the deformation uniformity inside the grains is improved. The established model can demonstrate the deformation history characteristics and structure inheritance of the continuous wire drawing process.
Vergleich zweier Ansätze zur Bekämpfung der kalten Progression: Tarifverschiebung vs. einkommensteuerpflichtige Kopfpauschale
Authors: Broer Michael , Stöwhase Sven 
Published: November 2023

Zusammenfassung
Die Bundesregierung hat im Jahr 2022 das Inflationsausgleichsgesetz verabschiedet, das zum Ausgleich der kalten Progression in der Einkommensteuer sowohl den Grundfreibetrag erhöht als auch die übrigen Tarifeckpunkte anpasst. Bei dem in Gesetzentwürfen verpflichtenden Hinweis auf Alternativen steht „keine“. Doch es gibt sehr wohl eine Alternative zur Tarifverschiebung, schreiben Michael Broer und Sven Stöwhase. Sie besteht darin, allein den Grundfreibetrag zu erhöhen, was gemäß höchstrichterlicher Rechtsprechung zwingend notwendig ist. Die fiskalischen Einnahmen, die durch den Verzicht auf eine Anpassung der übrigen Tarifeckpunkte zustande kommen, werden dann über eine steuerpflichtige Kopfpauschale an die Steuerpflichtigen ausgeschüttet, ähnlich wie im Fall der Energiepauschale im Jahr 2022. Es zeigt sich beim Vergleich, dass gerade einkommensschwache Steuerzahler, die von der Inflation aktuell besonders belastet werden, von einer Kopfpauschalenlösung profitieren würden.
Studies on the acidification of carbonate waste stream for separation of di-butyl phosphate and recovery of metal
Authors: Mishra Satyabrata , Pankaj  , Patra Chayan , Ghosh Debojyoti , Desigan Narasimhan , Velavendan Periyakaruppan , Venkatesan Konda Athmaram , Krishnamurthy Ananthasivan 
Published: November 2023

Abstract
The aqueous waste generated during the treatment of Purex lean organic phase with alkaline carbonate solution contains washable degradation products and actinides in the form of carbonate complex. Management of such aqueous waste demands quantitative removal of the main degradation product, dibutyl phosphate (HDBP) and actinides from aqueous solution. In this context, batch studies have been carried out on the separation of HDBP from aqueous solution using n-dodecane (n-DD). For this purpose, the extraction behaviour of HDBP in n-DD was studied after acidification of alkaline carbonate solution with nitric acid. The studies with simulated waste containing HDBP and U(VI) nitrate showed the loss of U(VI) as precipitate during acidification as the uranium–DBP was poorly soluble in aqueous phase. However, the loss of U(VI) decreased with increase of aqueous phase acidity showing that the adjusted acidity of the carbonate waste plays an important role in the recovery of actinides.
The nucleolar protein GNL3 prevents resection of stalled replication forks
Authors: Lebdy Rana , Canut Marine , Patouillard Julie , Cadoret Jean‐Charles , Letessier Anne , Ammar Josiane , Basbous Jihane , Urbach Serge , Miotto Benoit , Constantinou Angelos , Abou Merhi Raghida , Ribeyre Cyril 
Published: November 2023

AbstractFaithful DNA replication requires specific proteins that protect replication forks and so prevent the formation of DNA lesions that may damage the genome. Identification of new proteins involved in this process is essential to understand how DNA lesions accumulate in cancer cells and how they tolerate them. Here, we show that human GNL3/nucleostemin, a GTP‐binding protein localized mostly in the nucleolus and highly expressed in cancer cells, prevents nuclease‐dependent resection of nascent DNA in response to replication stress. We demonstrate that inhibiting origin firing reduces resection. This suggests that the heightened replication origin activation observed upon GNL3 depletion largely drives the observed DNA resection probably due to the exhaustion of the available RPA pool. We show that GNL3 and DNA replication initiation factor ORC2 interact in the nucleolus and that the concentration of GNL3 in the nucleolus is required to limit DNA resection. We propose that the control of origin firing by GNL3 through the sequestration of ORC2 in the nucleolus is critical to prevent nascent DNA resection in response to replication stress.
Sex steroid levels in corresponding cerebrospinal fluid and serum samples quantified by mass spectrometry in men
Authors: Ryberg Henrik , Norlén Anna-Karin , Landin Andreas , Johansson Per , Salman Zeinab , Wallin Anders , Svensson Johan , Ohlsson Claes 
Published: November 2023

Objective
Sex steroids exert important biological functions within the CNS, but the underlying mechanisms are poorly understood. The contribution of circulating sex steroids to the levels in CNS tissue and cerebrospinal fluid (CSF) has been sparsely investigated in human and with inconclusive results. This could partly be due to lack of sensitive validated assays. To address this, we validated a gas chromatography–tandem mass spectrometry (GC-MS/MS) assay for quantification of sex steroid hormones/precursors in CSF.

Methods
GC-MS/MS quantification of dihydrotestosterone (DHT, CSF lower limit of quantification, 1.5 pg/mL), testosterone (4.9), estrone (E1, 0.88), estradiol (E2, 0.25), dehydroepiandrosterone (DHEA, 38.4), androstenedione (4D, 22.3), and progesterone (P, 4.2) in CSF, and corresponding serum samples from 47 men.

Results
Analyses of CSF revealed that DHEA was the major sex steroid (73.5 ± 31.7 pg/mL) followed by 4D (61.4 ± 29.6 pg/mL) and testosterone (49.5 ± 18.9 pg/mL). The CSF levels of DHT, E2, and E1 were substantially lower, and P was in general not detectable in CSF. For all sex steroids except E2, strong associations between corresponding CSF and serum levels were observed. We propose that testosteronein CSF is derived from circulating testosterone, DHT in CSF is from local conversion from testosterone, while E2 in CSF is from local conversion from 4D in CNS.

Conclusions
We describe the first thoroughly validated highly sensitive mass spectrometric assay for a broad sex steroid hormone panel suitable for human CSF. This assay constitutes a new tool for investigation of the role of sex steroid hormones in the human CNS.

Significance statement
In this study, a fully validated highly sensitive mass spectrometric assay for sex steroids was applied to human CSF. The results were used to describe the relative contribution of peripheral circulating sex steroids together with locally transformation of sex steroids to the levels in CSF. The results are of importance to understand the biological processes of the human brain.
Muscle Architecture of Leg Muscles: Functional and Clinical Significance
Authors: Kaur Gurpreet , Lalwani Rekha , Khan Manal M. , Athavale Sunita A 
Published: November 2023

Background. Architectural properties of the muscles are the prime predictors of functional attributes and force-generating capacity of the muscles. This data is vital for musculoskeletal modelling and selecting the appropriate muscle–tendon units for tendon transfers.Cadaveric data for architectural properties is the gold standard and primary input for musculoskeletal modelling. There is a paucity of these datasets, especially in the leg muscles.Methods. Sixty muscles of the anterior and lateral compartments from twelve formalin-fixed lower limbs were studied for gross architecture, including the peculiar fibre arrangements and architectural properties of muscles. Muscle weight, muscle length, fibre length, pennation angle and sarcomere length were measured. Normalised fibre length, fibre length to muscle length ratio (FL/ML ratio), and the physiological cross-sectional area (PCSA) were calculated from the obtained data.Results. Muscles displayed a combination of architectural strategies and were partly fusiform and partly pennate. The tibialis anterior and peroneus longus were the heaviest muscles in their respective compartments and showed more extensive origin from the nearby deep facial sheets.Long fibre length and less pennation angle were seen in muscles of the extensor compartment. Potential muscle power was highest in the tibialis anterior and peroneus longus and least in the extensor hallucis longus.Conclusions. Arching of the foot and eversion are peculiar to humans and recent in evolution. Due to the functional demand of maintaining the medial longitudinal arch and eversion, the tibialis anterior and peroneus longus have more muscle weight and larger physiological cross-sectional area and are potentially more powerful.Extensor compartment muscles were architecturally more suited for excursions because of the long fibre length and less pennation angle.This study contributes baseline normative data for musculoskeletal modelling platforms and simulation tools – an emerging area in biomechanics and tendon transfers.
Medial patellofemoral ligament rekonstrüksiyonu sonrası kalça abduktör kas kuvvetlendirme egzersizlerinin diz fonksiyonu üzerine etkisi
Authors: ULUSOY Burak , ERCAN Niyazi , ULAŞ Efehan , AKMEŞE Ramazan , ERGUN Nevin 
Published: November 2023

Amaç: Bu çalışmanın amacı, medial patellofemoral ligament rekonstrüksiyonu geçirmiş hastalarda diz kas kuvvetlendirme egzersiz programına ek olarak yapılan kalça abduktör kuvvetlendirme egzersizlerinin fonksiyonel iyileşme üzerine etkisini araştırmak idi.
Yöntem: Çalışmaya 30 hasta dahil edildi. Hastalar randomize olarak diz kas kuvvetlendirme egzersiz grubu ve diz kuvvetlendirme egzersizlerine ek olarak kalça abduktör egzersiz grubuna ayrılarak 12 haftalık egzersiz programına dahil edildi. Hastaların preoperatif, postoperatif 3., 6. ve 12. aylarda diz fonksiyonları Kujala, (International Knee Documentation Committee) Subjektif Diz Değerlendirme Formu, Tegner ve Lysholm skorları ile değerlendirildi.
Bulgular: Diz skorları preoperatif dönemde gruplar arasında benzerdi (p>0,05). Kontrol grubuna kıyasla, 6. ve 12. aylarda Kujala (6. ay: p=0,03, 12. ay: p=0,03), International Knee Documentation Committee Subjektif Diz Değerlendirme Formu (3. ay: p=0,01, 6. ay: p=0,01, 12. ay: p=0,03) ve Lysholm (3. ay: p=0,04, 6. ay: p=0,04, 12. ay: p=0,01) skorları çalışma grubunda daha yüksek bulundu. Benzer şekilde, Tegner aktivite skoru çalışma grubunda, cerrahi sonrası 12. ayda daha yüksek idi (p=0,04).
Sonuç: Medial patellofemoral ligament rekonstrüksiyonu geçirmiş bireylerde diz kuvvetlendirme egzersiz programına ek olarak yapılan kalça abduktör kuvvetlendirme egzersizleri diz fonksiyonlarının iyileşmesi açısından sadece diz kuvvetlendirme egzersizlerine kıyasla daha etkiliydi. Bu nedenle rehabilitasyon programına kalça abduktör egzersizlerin dahil edilmesi, performansın gelişmesi açısından önemli olacaktır.
Kronik konstipasyonu olan kadınlarda konstipasyon şiddeti ile fiziksel aktivite seviyesi, vücut kütle indeksi, bel/kalça oranı ve yaşam kalitesi arasındaki ilişki
Authors: KARAASLAN Yasemin , OGUTMEN KOC Deniz , TOPRAK ÇELENAY Şeyda 
Published: November 2023

Amaç: Kronik konstipasyonu olan kadınlarda konstipasyon şiddeti ile fiziksel aktivite seviyesi, vücut kütle indeksi (VKİ), bel/kalça oranı ve yaşam kalitesi arasındaki ilişkiyi incelemekti.
Yöntem: Kronik konstipasyonu olan 115 kadının konstipasyon şiddeti Konstipasyon Ciddiyet Ölçeği (KCÖ) ile, fiziksel aktivite seviyesi Uluslararası Fiziksel Aktivite Anketi-Kısa Form (UFAA-KF) ile, VKİ vücut ağırlığı / boy uzunluğu hesabı ile, bel/kalça oranı mezura ile ve yaşam kalitesi Nottingham Sağlık Profili (NSP) ile değerlendirildi.
Bulgular: KCÖ-dışkı tıkanıklığı, KCÖ-kalın barsak tembelliği, KCÖ-ağrı ve KCÖ-toplam skorları ile UFAA-KF skoru arasında negatif ilişkiler (sırasıyla rho=-0,482, -0,364, -0,366 ve -0,538) bulunurken, bel/kalça oranı ile (KCÖ-kalın barsak tembelliği hariç) arasında pozitif ilişkiler (sırasıyla rho=0,288, 0,374 ve 0,322) bulundu (p
Reserva de carbono en sistemas silvopastoriles: Un estudio en el Medio Sinú, Colombia
Authors: Contreras-Santos Jose Luis , Falla-Guzmán Cindy Katherine , Rodríguez José Luis , Fernando-Garrido Jeyson , Martínez-Atencia Judith , Aguayo-Ulloa Lorena 
Published: November 2023

Introducción. Los sistemas silvopastoriles tienen un papel importante en la producción ganadera, aportan beneficios a los componentes animal y edáfico, ofrecen servicios ambientales como la captura de carbono atmosférico en el suelo y la biomasa. Objetivo. Evaluar la capacidad de captura de carbono atmosférico en tres sistemas de diferentes complejidades enfocados a la producción ganadera, en el norte de Colombia. Materiales y métodos. El estudio se llevó a cabo en el Centro de Investigación Turipaná de la Corporación Colombiana de Investigación Agropecuaria entre 2019 y 2021. Se evaluaron parámetros dasométricos del componente arbóreo/arbustivo. Se estimó la biomasa aérea (CBA) y subterránea (CBR) de estas especies con modelos alométricos. Se cuantificó la biomasa de hojarasca caída (CLIT) y el carbono orgánico en el suelo hasta los 30 cm, con lecturas cada 10 cm, por el método de combustión y carbono total acumulado. El diseño correspondió a bloques completos al azar, con tres tratamientos y cuatro repeticiones. Los tratamientos correspondieron a dos sistemas silvopastoriles (SSP) de diferente complejidad y una gramínea sin árboles (Pr). Resultados. La biomasa aérea fue mayor dentro los SSP (2,18±1,13, 4,51±3,76 t ha-1 C) que en Pr (0,19±0,09 t ha-1 C). En SSP2 se presentó la mayor acumulación de CBR (1,16±3,76 t ha-1 C) y CLIT (3,09±2,45 t ha-1 C). Los valores de carbono orgánico acumulado en el suelo (COS), mostraron mayor acumulación en el primer estrato. El COS representó en los tres sistemas más del 70 % del aporte total en carbono acumulado. Conclusión. Bajo las condiciones ambientales de bosque seco tropical húmedo, los sistemas silvopastoriles aumentaron la reserva de carbono atmosférico en el suelo y en la biomasa; el uso de SSP es una estrategia en la mitigación de gases de efecto invernadero en el sistema productivo ganadero.
Side effects following administration of the Gam-COVID-Vac in Montenegro
Authors: Dabanovic Vera 
Published: November 2023

Introduction. In Montenegro, vaccination against COVID-19 infection began with the use of Gam-COVID-Vac, which was not approved for emergency use before the end of clinical trials, by the Food and Drug Administration and the European Medicines Agency. Therefore, it is necessary to emphasize the adverse effects.
Materials and methods. For the purpose of this study, there were collected data from national adverse events reporting form for Gam-COVID-Vac obtained from the Health Institution Pharmacy of Montenegro — Montefarm, as the holder of permits for these vaccines. Results. For the period March 1, 2021 to February 13, 2022, after administration of 16 756 doses of vaccine Gam-COVID, a total of 220 case reports, or 716 adverse effects were recorded. The mean age of vaccinated individuals who reported adverse effects was 40.79±11.35 years. Totally, 79.55% females versus 20.45% males reported side effects post-vaccination. The most common adverse reaction was pyrexia (79.55%). Other very common adverse effects were as follows: injection site pain (38.18%), headache (33.18%), myalgia (32.27%), malaise (31.82%), fever (30.45%), arthralgia (22.73%) as well as swelling and redness at the site of application (15.91%). Less common adverse effects were nausea, pain in extremity, diarrhea, dizziness, fatigue, sore throat and labial herpes. Serious adverse effects were recorded in 8 cases including tinnitus, thrombophlebitis, hypotension, chest pain, palpitations and peripheral cyanosis related to specific comorbidities.
Conclusions. After the administration of Gam-COVID vaccine, the population in Montenegro experienced mild to moderate adverse effects, with rare serious transient adverse effects related to specific comorbidities. The data presented here on investigating Gam-COVID-Vac caccine verified good safety profile and high tolerability evidenced by the statistics analysis as lacked COVID-19-associated hospitalizations or deaths.
Integração dos Objetivos de Desenvolvimento Sustentável na gestão da sustentabilidade do setor de suco de laranja do Brasil
Authors: Bettini Mariana Manente , Silva Filho Cândido Ferreira da , Conti Diego de Melo , Benedicto Samuel Carvalho De 
Published: November 2023

O modelo econômico atual tem levado os recursos naturais à exaustão e, com isso, cresce a pressão por parte dos clientes e demais partes interessadas para que as empresas atuem de forma mais sustentável. Visando atender esta demanda e enxergando os potenciais benefícios advindos da adoção das práticas sustentáveis, como maior aproximação com seus stakeholders e maior estabilidade em períodos de crise, alguns setores passam a apresentar engajamento no tema. Por isso, no decorrer das últimas décadas, alguns conceitos que visam aproximar o mundo corporativo das práticas sustentáveis foram apresentados e passaram por evoluções. O setor de suco de laranja do Brasil, área em que o país é destaque global, apresenta engajamento sobre o tema?. Face ao exposto, objetivo da pesquisa foi verificar como se dá a adesão das maiores empresas do setor de suco de laranja aos Objetivos do Desenvolvimento Sustentável (ODS) das Nações Unidas, como consta na Agenda 2030. A metodologia utilizada é caracterizada como qualitativa, bibliográfica, descritiva e documental. Os resultados mostram que as maiores empresas do setor têm se esforçado para promover a integração dos Objetivos de Desenvolvimento Sustentável (ODS) na gestão dos negócios, contudo, este processo se dá em ritmos distintos.
Profile of Australian Yoga Providers: Results from the Practitioner Research and Collaboration Initiative (PRACI) Workforce Survey
Authors: Maddela Sridhar , Frawley Jane , Adams Jon , Steel Amie , Sibbritt David 
Published: November 2023

Abstract
Yoga is becoming increasingly popular in Western countries, particularly for maintaining health and managing chronic noncommunicable diseases. Yoga providers, including yoga teachers, yoga therapists, and healthcare workers using yoga in clinical practice, are vital in facilitating group and personalized yoga sessions. This article aims to meet an unmet need to profile the sociodemographic and practice characteristics of yoga providers in Australia. A workforce survey was distributed electronically to yoga providers throughout Australia via the Practitioner Research and Collaboration Initiative (PRACI). The yoga providers’ sociodemographic and practice characteristics, professional qualifications, and practice interests reported in the survey were analyzed. The study reveals a predominantly female, middle-aged, and tertiary-educated workforce. The yoga providers considered themselves group educators offering complementary and integrative health services. Typically, they had worked part-time as a solo provider for more than 10 years since acquiring their first yoga qualification. This study represents the first exploration of the Australian yoga provider workforce on a national level. It suggests that some Australian yoga providers are highly qualified professionals integrating with healthcare modalities in education and practice. The landscape of yoga providers in Australia needs further investigation.