bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lactobacillus intestinalis/Lactobacillus rhamnosus protects against AFB1-induced liver damage: involvement of intestinal mucosal barrier
Authors: Chen Yuanyuan , Liu Honglin , An Tianhui , Wu Qian , Zhang Hongtao , Loor Juan J. , Cheng Jiaxin , Wang Junqi , Sun Jian 
Published: September 2023

AbstractAflatoxin B1 (AFB1) is a widely spread mycotoxin that poses a threat to the healthy to human and animals. The liver is the main target organ for AFB1-induced damage, primarily causing inflammatory injury and oxidative stress. When AFB1 enters the body, it can damage the intestinal barrier function, and its metabolites are transported to the liver. Therefore, the damage to the liver is closely associated with intestinal barrier impairment. Lactobacillus plays a crucial role in mitigating liver damage by improving the intestinal barrier function. In our previous report, we reported that Lactobacillus reduces liver damage caused by AFB1. However, it is still unclear how the intestinal barrier contributes to the protective effects of Lactobacillus against AFB1. To investigate the protective effects and intestinal barrier mechanisms of Lactobacillus intestinals /rhamnosus against AFB1-induced liver damage, we orally administered AFB1 and Lactobacillus intestinals/rhamnosus to male SD rats. Then the body weight, organ index, histopathological changes in the liver and gut, liver and kidney function indicators, intestinal mucosal barrier indicators, serum AFB1 content and inflammatory factors, liver oxidative stress index, and short-chain fatty acids content were analyzed. Our findings demonstrate that exposure to AFB1 resulted in changes in liver histopathology and biochemical functions, altered inflammatory response and oxidative stress, compromised the intestinal mucosal barrier, and induced the accumulation of inflammatory factor and inflammation in the liver. However, supplementation with Lactobacillus intestinals or Lactobacillus rhamnosus significantly prevented AFB1-induced liver injury, alleviated histopathological changes and hepatic injury by the maintenance of intestinal mucosal barrier integrity.
Oncofertility awareness among primary care physicians in India
Authors: Tholeti Prathima , Uppangala Shubhashree , Jayaram Rajesh Kumar , Udupa Karthik S , Kalthur Guruprasad , Spears Norah , Woodruff Teresa , Adiga Satish K 
Published: September 2023

Background: Primary care physicians not only coordinate referrals to oncology services but can play a crucial role in successful fertility preservation referrals in cancer-diagnosed patients. Hence, it is important to assess their knowledge and attitudes towards fertility preservation. Methods: An eighteen-item oncofertility survey was administered to primary care physicians between May 2019 to September 2020. Results: A total of forty-six responses were received and analysed. About 60% of primary care physicians did not have adequate knowledge about available fertility preservation options and only 26-32% were aware of international guidelines recommending fertility preservation in cancer patients. Conclusions: Imparting awareness and knowledge of fertility preservation and its options to primary care physicians could enable an integrated cancer care model while also facilitating successful oncofertility referrals in countries like India.
How resilient were family planning programs during the COVID-19 pandemic? Evidence from 70 countries
Authors: Hardee Karen , Rosenberg Rebecca , Ross John , Zosa-Feranil Imelda 
Published: September 2023

Background: At the beginning of the COVID-19 pandemic fears of severe disruptions to family planning (FP) and access to services abounded. This paper uses a unique data source, a special Supplement added to the 2021 round of the National Composite Index for Family Planning (NCIFP), to assess in depth the resilience of FP programs in the face of the COVID-19 pandemic across 70 countries spanning six regions. Methods: The 2021 NCIFP included 961 key informants who were asked questions to assess interference in the countries’ ability to achieve objectives, ability to maintain commitment to FP, and availability of information and services. Open ended responses added context. Results: All programs were affected; the magnitude of effects varies by region and country. While the average resilience score, at 47 out of 100, implies middling levels of resilience, further analysis showed that despite interference in many components of programming, with some exceptions, the COVID-19 pandemic generally did not diminish government commitment to FP and programs remained resilient in providing access to services. Common themes mentioned by 178 respondents (18.5% of respondents) included: fear of infection; disruption of services / difficulty with lockdown and travel restrictions; staff / facilities diverted to COVID-19; access to reproductive health services and contraceptive methods affected; shifts in services / outreach; interference with logistics & supplies, training & supervision, and M&E; lack of attention to FP/sexual reproductive health; financing reduced or diverted; and effects on existing partnerships. A strong enabling environment for FP, which the NCIFP is designed to measure, was positively correlated with continued government commitment and access to contraceptive methods during COVID-19. Conclusion: These findings are instructive for programming: it will face challenges and ‘interference’ when unanticipated shocks like COVID-19 occur, with strong FP programs best prepared to exhibit resilience.
ediblecity: an R package to model and estimate the benefits of urban agriculture
Authors: Pueyo-Ros Josep , Comas Joaquim , Corominas Lluís 
Published: September 2023

Urban agriculture is gaining attraction to become one of the pillars of the urban ecological transition and to increase food security in an urbanized planet. However, there is a lack of systematic quantification of the benefits provided by urban agriculture solutions. In this paper, we present an R package to estimate several indicators related to benefits of urban agriculture. The goal is to provide a tool for researchers and practitioners interested in the impacts of urban agriculture. The ediblecity package provides functions to calculate 8 indicators: urban heat island, runoff prevention, green areas accessibility, NO2 sequestration, jobs created in commercial gardens, volunteers involved in community gardens, green per capita and, finally, food production. Moreover, the package also provides a function to generate scenarios with different implementations of urban agriculture. We illustrate the use of the package by comparing three scenarios in a neighborhood of Girona (Spain), which is included in the package as an example dataset. There, we compare scenarios with an increasing amount of urban agriculture solutions. The ediblecity package is open-source software. This allows other R developers to contribute to the package, providing new functionalities or improving the existing ones.
Factors affecting reproductive behaviour in Estonia in the 21st century
Authors: Tiit Ene-Margit 
Published: September 2023

In Estonia where the population size is quite small (less than a million ethnic Estonians) the low birth rate has been a problem throughout known history.
In Estonia as in other Eastern European countries, the so-called transition shock appeared in the 1990s after regaining independence. As a result of the shock, the birth rate fell sharply; the number of births in 1994–2000 was twice less than the number of births ten years earlier, in 1984–1990. Intensive migration also lasted for about 25 years, and, as a result, the population of Estonia decreased by more than for 250 000 people (one sixth of the population). The ethnic structure of the population of Estonia also changed. Depending on the direction and volume of foreign migration, the share of ethnic Estonians in the population, which was 61.5% in 1991, increased to 67.9% by the turn of the century.
Postponing of births has been an important trend throughout the world, including in Estonia, in recent decades. In Estonia the average age of mothers who gave birth increased from 1991 to 2021 by almost 6 years. This means that, for 30 years, nearly a fifth of children were not born each year. The total fertility rate depends on the change in the average childbearing age. When the childbearing age increases (which has been happening in Estonia during the last 30 years), the total fertility rate (TFR) underestimates the average number of children born to a woman in her lifetime. Although TFR is relatively low in Estonia now, oscillating between 1.5 and 1.7, this does not mean that the average number of children born by a woman is so low.
If a cohort of women (e.g., women born 45–49 years ago) has passed the fertile age, it is possible to determine the average number of children whom they actually gave birth during their lifetime. This indicator gives a much more optimistic picture about the fertility behaviour of Estonian women than TFR.
Ethnic Estonian women are more active in giving birth than the women of other ethnic origins. On average, Estonian women aged 40+ have given birth to 2 children.
Rozmowa o współczesnej tożsamości polskich Żydów
Authors: Weżgowiec Barbara 
Published: September 2023

DIALOG ABOUT THE MODERN IDENTITY OF POLISH JEWS: AROUND THE POSTMEMORY NARRATIONS IN DOCUMENTARY BY MIKOŁAJ GRYNBERG THE PROOF OF IDENTITY
The 2021 documentary The Proof of Identity marked the directorial debut of Mikołaj Grynberg. In this film, the director attempts to depict the unique experience of being a Polish Jew, while also exploring the intricate nature of an essentially dual (Polish-Jewish or Jewish-Polish) identity. The aim of this article is to elucidate the framework employed by both the director and his characters in recounting their search for a proof of identity, which entails coming to terms with personal (and familial) memory. The article delves into the “conflicts” and “negotiations” that arise in the interviewed individuals’ considerations of identity within the context of postmemory. Central to the film is the director’s fundamental question: What does it mean to be a Jew in present-time Poland? An integral aspect of these considerations is the examination of the fact that the author, who is primarily known as a writer, chose the form of documentary, with the interview as its special type.
„Wojny pamięci” w literaturze rosyjskiej. Twórczość Siergieja Lebiediewa
Authors: Kowalska Martyna 
Published: September 2023

“MEMORY WARS” IN RUSSIAN LITERATURE: SERGEI LEBEDEV’S WORKS
Sergei Lebedev’s tetralogy – Oblivion (2010), The Year of the Comet (2014), People of August (2015), and The Goose Fritz (2018) – is considered a multigenerational novel. This genre of literature can be seen as a medium for collective memory, offering an avenue for reinterpreting the experiences of past generations as an alternative to official historical narratives (referred to as “first memory”). The primary focus of this article centers on Lebedev’s oeuvre in the context of the ongoing “memory wars” within Russian culture. Lebedev’s works are characterized by an intensified historical consciousness that revolves around the key events of the 20th century. However, the objective is not an inquiry into historical truth sensu stricto, but rather an exploration of post-trauma, which is Russians’ unwanted and rejected heritage. Consequently, the past becomes a catalyst for contemplating the current condition of Russian society. Lebedev’s work encourages deeper reflection on the causes of the “memory wars” and the consequences of divisions between individual and collective memory.
Przechwycić traumę, czyli Aleksandra Petrova opowieść o serbskim cierpieniu
Authors: Giergiel Sabina 
Published: September 2023

TO SEIZE THE TRAUMA: ALEKSANDAR PETROV’S STORY ABOUT THE SERBIAN SUFFERING
The paper focuses on Aleksandar Petrov’s novel Kao zlato u vatri, originally published by this Serbian author in 1998. The novel’s main characters represent diverse ethnic groups inhabiting the Balkans ( Jews, Serbians, Russians), and their fortunes intertwined with the tumultuous events of 20th century history, namely WWII and the Yugoslav Wars of the 1990s. The primary objective of the article is to address the question of whether it is feasible to apply Michael Rothberg’s model of multifaceted memory in a scenario involving distinct memory communities (such as Serbs, Croatians, and possibly Jews), characterized by a specific proximity (primarily territorial, historical and rooted in past coexistence within one national entity) and where relations are predominantly shaped by unresolved past grievances and mutual accusations of guilt.
Immediate effect of stretched myofascial dry needling on the myofascial trigger point in the upper trapezius muscle: a case report
Authors: Rajput Priyanka , Kalia Varun 
Published: September 2023

Background/Aims A myofascial trigger point is a hyperirritable spot, usually within a taut band of skeletal muscle, that is painful on compression and can cause motor dysfunction. The authors present a case report of a 21-year-old woman with myofascial trigger points in the upper trapezius muscle who reported a pre-assessment pain score of 7 on the visual analogue scale, a pressure pain threshold of 1.32 kg/cm2 and a reduction in all cervical ranges of motion. To provide more immediate results in comparison to traditional dry needling, the upper trapezius muscle was kept in a stretched position and then dry needling was performed. Methods With the patient lying in the prone position, the therapist stretched the right upper trapezius muscle. Fast in-and-out movements of dry needling were performed to target multiple active myofascial trigger points until the first visible local twitch response occurred. Results Immediately after the procedure, the patient's pain level reduced to a score of 3 on the visual analogue scale, the patient's pressure pain threshold increased to 3.07 kg/cm2, and cervical ranges of motions increased between 10 and 20°. Conclusions Stretched myofascial dry needling is effective to treat symptoms immediately related to myofascial trigger points in the upper trapezius muscle, although further research is needed.
Provider-led community antiretroviral therapy distribution in Malawi: Retrospective cohort study of retention, viral load suppression and costs
Authors: Songo John , Whitehead Hannah S. , Nichols Brooke E. , Makwaya Amos , Njala Joseph , Phiri Sam , Hoffman Risa M. , Dovel Kathryn , Phiri Khumbo , van Oosterhout Joep J. 
Published: September 2023

Background
Outcomes of community antiretroviral therapy (ART) distribution (CAD), in which provider–led ART teams deliver integrated HIV services at health posts in communities, have been mixed in sub-Saharan African countries. CAD outcomes and costs relative to facility-based care have not been reported from Malawi.

Methods
We performed a retrospective cohort study in two Malawian districts (Lilongwe and Chikwawa districts), comparing CAD with facility-based ART care. We selected an equal number of clients in CAD and facility-based care who were aged >13 years, had an undetectable viral load (VL) result in the last year and were stable on first-line ART for ≥1 year. We compared retention in care (alive and no period of ≥60 days without ART) using Kaplan-Meier survival analysis and Cox regression and maintenance of VL suppression (<1,000 copies/mL) during follow-up using logistic regression. We also compared costs (in US$) from the health system and client perspectives for the two models of care. Data were collected in October and November 2020.

Results
700 ART clients (350 CAD, 350 facility-based) were included. The median age was 43 years (IQR 36–51), median duration on ART was 7 years (IQR 4–9), and 75% were female. Retention in care did not differ significantly between clients in CAD (89.4% retained) and facility-based care (89.3%), p = 0.95. No significant difference in maintenance of VL suppression were observed between CAD and facility-based care (aOR: 1.24, 95% CI: 0.47–3.20, p = 0.70). CAD resulted in slightly higher health system costs than facility-based care: $118/year vs. $108/year per person accessing care; and $133/year vs. $122/year per person retained in care. CAD decreased individual client costs compared to facility-based care: $3.20/year vs. $11.40/year per person accessing care; and $3.60/year vs. $12.90/year per person retained in care.

Conclusion
Clients in provider-led CAD care in Malawi had very good retention in care and VL suppression outcomes, similar to clients receiving facility-based care. While health system costs were somewhat higher with CAD, costs for clients were reduced substantially. More research is needed to understand the impact of other differentiated service delivery models on costs for the health system and clients.
Development of a checklist to assess potentially effective components in combined lifestyle interventions for children with overweight or obesity
Authors: Saat Jenneke J. E. H. , Fransen Gerdine A. J. , Naumann Elke , van der Velden Koos , Assendelft Willem J. J. 
Published: September 2023

Background
In the Netherlands, Combined Lifestyle Interventions (CLIs), offered in primary care, aim to reduce the number of children with overweight or obesity. CLIs are carried out by a multidisciplinary team and focus on dietary advice and guidance, exercise and behaviour change. These CLIs are not uniformly designed and vary in protocols to suit the local circumstances. Due to the variation in content of CLIs it is difficult to investigate their effectiveness. To enable a proper evaluation of CLIs, we first need to unravel the ‘black boxes’ of CLIs by identifying the various potentially effective components.

Methods
First of all we identified potentially effective components in literature. Subsequently we organized an online consultation with experts with diverse backgrounds and asked if they could add potentially effective components. These components were then assembled into a checklist meant to determine the presence or absence of potentially effective components in CLIs for children.

Results
42 experts participated. We identified 65 potentially effective components for CLIs for children with overweight or obesity that we categorized into three themes: content, organisation and implementation.

Conclusions
Based on literature and expert opinions we developed a practical 65-item checklist to determine the presence of potentially effective components in a CLI. This checklist can be used in the development of CLIs as well as evaluation of CLIs.
Effects of different sponge implantation methods of negative pressure wound therapy on wound healing of deep surgical site infection after spinal surgery
Authors: Wang Jingming , Xing Hao , Chang Zhengqi 
Published: September 2023

Purpose
After spinal surgery, negative pressure wound treatment (NPWT) improves deep surgical site infection (DSSI) wound healing. This research compared the healing benefits of two sponge implantation strategies in NPWT for DSSI.

Methods
21 patients with DSSI utilized NPWT to improve wound healing following spine surgery were followed from January 1, 2012 to December 31, 2021. After antibiotic treatment failure, all these patients with DSSI received extensive debridement and NPWT. They are grouped by sponge placement method: centripetal reduction and segment reduction. The two groups’ hospital stays, NPWT replacement frequency, wound healing time, healing speed, and quality of wound healing (POSAS score) were compared.

Results
All patients had been cured by the end of December 2022, and the mean follow-up time was 57.48 ± 29.6 months. Surgical incision length did not vary across groups (15.75±7.61 vs. 15.46±7.38 cm, P = 0.747). The segmental reduction approach had shorter hospital stay and NPWT treatment times than the centripetal reduction method (39.25±16.04 vs. 77.38±37.24 days, P = 0.027). Although there is no statistically significant difference, the mean wound healing duration of segmental reduction group is faster than that of centripetal reduction group (0.82±0.39 vs 0.45±0.28 cm/d, P = 0.238), wound healing quality (POSAS) (33.54±8.63 vs 48.13±12.17, P = 0.408) is better in segmental reduction group, and NPWT replacement frequency (2.62 ± 1.04 vs 3.88 ± 1.25, P < .915) is smaller in segmental reduction group.

Conclusions
NPWT heals wounds and controls infection. Segmental reduction method accelerates wound healing, reduces hospital stay, and improves wound quality compared to central reduction method.
Molecular characterization and genetic diversity of Wolbachia endosymbionts in bed bugs (Hemiptera; Cimicidae) collected in Paris
Authors: Chebbah Dahlia , Hamarsheh Omar , Sereno Denis , Elissa Nohal , Brun Sophie , Jan Julie , Izri Arezki , Akhoundi Mohammad 
Published: September 2023

Purpose
This study aimed to investigate the genetic diversity of Wolbachia in field-caught bed bug species in Paris areas.

Methods
The bed bug specimens were captured from various infested localities in Paris and surrounding cities. They belonged to diverse life stages, including egg, nymph, and adult. They were then identified using morphological and molecular approaches. Furthermore, Wolbachia was detected, and its genetic diversity was investigated by conventional PCR of 16S-rRNA and Wolbachia surface protein (wsp) genes.

Results
A total of 256 bed bug specimens belonging to various life stages [adult (183 specimens), nymph (48), and egg (25)] were captured from seven private apartments, five social apartments, three houses, two immigrant residences, and one retirement home situated in 10 districts of Paris and 8 surrounding cities. They were identified as Cimex lectularius (237 specimens) and C. hemipterus (19) using morphological and molecular approaches. The presence and diversity of Wolbachia were ascertained by targeting 16S-rRNA and wsp genes. Based on molecular analysis, 182 and 148 out of 256 processed specimens were positive by amplifying 16S-rRNA and wsp fragments, respectively. The inferred phylogenetic analysis with 16S-rRNA and wsp sequences displayed monophyletic Wolbachia strains clustering each one in three populations. The median-joining network, including the Wolbachia 16S-rRNA and wsp sequences of C. lectularius and C. hemipterous specimens, indicated a significant genetic differentiation among these populations in Paris areas which was consent with Neighbor-Joining analyses. A phylogenetic analysis of our heterogenic Wolbachia sequences with those reported from other arthropod species confirmed their belonging to supergroup F. Moreover, no difference between Wolbachia sequences from eggs, nymphs, and adults belonging to the same clade and between Wolbachia sequences of C. lectularius and C. hemipterus were observed after sequence alignment. Furthermore, no significant correlation was found between multiple geographical locations (or accomodation type) where bed bugs were collected and the genetic diversity of Wolbachia.

Conclusions
We highlight a significant heterogeneity within Wolbachia symbionts detected in C. lectularius and C. hemipterus. No correlation between Wolbachia species and bed bug species (C. lectularius versus C. hemipterus), physiological stages (egg, nymph, and adult), and sampling location was recorded in this study.