bluuebunny/crossref_metadata_2025_split huggingface dataset:
Complete mesocolic excision for right colon cancer: Is D3 lymphadenectomy necessary?
Authors: Desouza Ashwin L. , Kazi Mufaddal M. , Nadkarni Shravan , Shetty Preethi , T Vipin , Saklani Avanish P. 
Published: November 2023

AbstractAimAlthough complete mesocolic excision (CME) for colon cancer is oncologically sound, to date, there has been no consensus on the extent of lymphadenectomy in radical right colectomy. This study essentially compared the perioperative and survival outcomes of CME with two templates of lymphadenectomy for right colon cancer.MethodThis was a propensity matched, retrospective analysis of a single centre, prospectively maintained database of all patients undergoing elective right colectomy for nonmetastatic, biopsy‐proven adenocarcinoma from November 2013 to October 2018. CME + D3 was adopted selectively, documented prospectively, and compared with patients undergoing CME + central vascular ligation (CVL). The only technical difference between the groups was the excision of the surgical trunk of Gillot in the CME + D3 group. Postoperative, long‐term outcomes and patterns of recurrence were compared between the groups.ResultsOf the 244 eligible patients, 88 (36.1%) and 156 (63.9%) underwent CME + D3 and CME + CVL, respectively. Matched groups (72 [CME + D3] vs. 108 [CME + CVL]) showed no difference in histology, tumour grade, postoperative complications, mortality, and hospital stay. CME + D3 was preferentially performed laparoscopically (35.2% vs. 9%), was associated with lower blood loss (215 mL vs. 297 mL, p = 0.001), higher nodal yield (31 vs. 25 nodes, p = 0.003) and a higher incidence of chyle leak (4 vs. 0, p = 0.013). At a median follow‐up of more than 57 months, there was no significant difference in local recurrence, disease‐free or overall survival.ConclusionIn this retrospective study, lymphadenectomy along the superior mesenteric vein, as a component of CME for right colon cancer, offered a higher nodal yield with no improvement in oncological outcome. Dissection of the SMV, over and above a D2 dissection, could therefore be restricted to specialized colorectal units until further studies establish the incremental oncological benefit of this extended lymphadenectomy or define a patient group in whom it is beneficial.
Does size matter? Hospital volume and resource use in paediatric diabetes care
Authors: de Vries Silvia A. G. , Bak Jessica C. G. , Mul Dick , Wouters Michel W. J. M. , Nieuwdorp Max , Verheugt Carianne L. , Sas Theo C. J. 
Published: November 2023

AbstractAimsPaediatric diabetes care has become increasingly specialised due to the multidisciplinary approach and technological developments. Guidelines recommend sufficient experience of treatment teams. This study evaluates associations between hospital volume and resource use and hospital expenditure in Dutch children with diabetes.MethodsRetrospective cohort study using hospital claims data of 5082 children treated across 44 Dutch hospitals (2019–2020). Hospitals were categorised into three categories; small (≥20–100 patients), medium (≥100–200 patients) and large (≥200 patients). All‐cause hospitalisations, consultations, technology and hospital expenditure were analysed and adjusted for age, sex, socio‐economic status (SES) and hospital of treatment.ResultsFewer hospitalisations were observed in large hospitals compared to small hospitals (OR 0.48; [95% CI 0.32–0.72]; p < 0.001). Median number of yearly paediatrician visits was 7 in large and 6 in small hospitals, the significance of which was attenuated in multilevel analysis (OR ≥7 consultations: 1.89; [95%CI 0.74–4.83]; p = 0.18). Technology use varies between individual hospitals, whereas pump usage and real‐time continuous glucose monitoring showed no significant differences between hospital volumes. Mean overall expenditure was highest in medium‐sized centres with €6434 per patient (IQR €2555–7955); the difference in diabetes care costs was not significant between hospital patient volumes.ConclusionsCare provision patterns vary by hospital patient volume. Large hospitals had the lowest hospitalisation rates. The use of diabetes technology was not different between hospital patient volumes. Medium‐sized hospitals showed the highest overall expenditure, but diabetes care costs were similar across hospital volumes.
Influence of model complexity, training collinearity, collinearity shift, predictor novelty and their interactions on ecological forecasting
Authors: Chen Xin , Liang Ye , Feng Xiao 
Published: November 2023

AbstractAimEcological forecasting is critical in understanding of ecological responses to climate change and is increasingly used in climate mitigation plans. The forecasts from correlative models can be challenged by model complexity, training collinearity, collinearity shift and novel conditions of predictors that are common during model extrapolation. The individual effect of these four factors has been investigated, but it is still unclear how these four factors interactively affect forecasting. To fill this gap, we conducted a comprehensive simulation experiment to quantify how the four factors interactively influence model forecasting.LocationSimulated regions.Time PeriodSimulated scenarios.MethodsWe modelled three response variables commonly used in ecological forecasting following normal, Poisson and binomial distributions as a function of three functional relationships that represented model complexity under three levels of training collinearity using generalized linear models. By calculating prediction error under 3,780,000 testing scenarios, we partitioned its variance to model complexity, training collinearity, collinearity shift, predictor novelty and their interactions.ResultsWe found that increased predictor novelty and collinearity shift degraded model performance, leading up to double prediction errors when a predictor's range increased by ~22% or when the correlation r between two predictors changed >~0.8 for the combination of high training collinearity and interaction functional relationship. Predictor novelty reduced the influence of collinearity shift on model performance, suggesting a negative interaction between them. This pattern was more pronounced under high model complexity and high training collinearity.Main ConclusionsThe accuracy of ecological forecasting using correlative models depends on model complexity, training collinearity, collinearity shift, predictor novelty and their interactions. Besides the consideration of parsimonious models and r of 0.7 in model training, our study further recommends a threshold of <22%–50% increased predictor range depending on training collinearity and/or <0.8 correlation change for making reliable forecasting.
Effect of galcanezumab in women with episodic migraine meeting criteria for menstrually related migraine: A post hoc analysis of EVOLVE‐1 and EVOLVE‐2
Authors: MacGregor E. Anne , Okonkwo Rose , Detke Holland C. , Polavieja Pepa , Fernandes Maria S. , Pavlovic Jelena M. 
Published: November 2023

AbstractBackgroundWe evaluated galcanezumab for migraine prevention in patients who met International Classification of Headache Disorders, 3rd edition criteria for menstrually related migraine (MRM).MethodsPatients were identified post hoc from three double‐blind, randomized, phase 3 clinical trials in patients with episodic migraine. Patients completed a 1‐month prospective baseline period and up to 6 months (EVOLVE‐1 and ‐2, studies pooled) of double‐blind treatment with galcanezumab (120 mg/month) or placebo. Menses and headache information were recorded by electronic daily diary. Patients with a migraine attack starting during the 5‐day perimenstrual interval (first day of bleeding ± 2 days) for ≥2 of their first three diary‐recorded menstrual cycles were categorized as having MRM. The primary efficacy measure was mean change in monthly migraine headache days from baseline, averaged over Months 4 through 6. Response rates, change in monthly perimenstrual migraine headache days, monthly non‐perimenstrual migraine headache days, and quality of life were also assessed.ResultsPost hoc MRM analysis criteria were met by 462/1133 women (41%). Mean (standard deviation) baseline monthly migraine headache days were 9.7 (±3.1; n = 146) for galcanezumab‐treated patients and 9.6 (±2.8; n = 316) for placebo‐treated patients. The mean change (standard error [SE]) in migraine headache days over Months 4 through 6 was −5.1 days (±0.39) for galcanezumab versus −3.2 (±0.35) for placebo (p < 0.001). The mean change (SE) in perimenstrual migraine headache days over Months 4 through 6 was −0.75 days (±0.08) for galcanezumab versus −0.49 (±0.07) for placebo (p = 0.004). For migraine headache days outside the perimenstrual period, the mean change in migraine headache days was −4.6 (±0.38) for galcanezumab and −2.8 (±0.33) for placebo (p < 0.001). Improvements in response rates and the Migraine‐Specific Quality of Life Questionnaire were also observed over Months 4 through 6.ConclusionGalcanezumab was effective for migraine prevention in women with MRM.
Orthodox Theology's Hide‐and‐Seek with Postcolonialism
Authors: Papathanasiou Athanasios N. 
Published: November 2023

AbstractAccording to the postcolonial approach, to understand today's world one must take into account modern colonialism (late 15th to mid‐20th centuries) as well as all other forms of colonialism. Orthodox theologians have only recently and on a small scale begun to use postcolonial analysis. However, Orthodox theology can contribute to the discussion and shed more light on both the historical experience and the future course of the debate. In particular, the postcolonial perspective can intersect with missionary praxis and missiology, as the Orthodox Church began to be seriously active in the missionary field (of sub‐Saharan Africa and the Far East) in the 1960s, that is, at the end of the classical colonial period. Its experience confirms that colonialism entails not only direct imposition on the colonized but also the colonized people's internalizing of the colonizers’ logic. The postcolonial approach thus invites self‐criticism. The obligation to be self‐critical is at the heart of the Orthodox tradition, despite the fact that it is often forgotten, resulting in nightmarish distortions and neo‐colonial attitudes. At the same time, the postcolonial perspective reinforces the liberating mission of the gospel and patristic theology in all human contexts. In this way, postcolonialism is called to come to a fruitful completion with anti‐colonialism and to contribute to the key demand of Orthodox ecclesiology, which is the formation of authentically local churches and not branches of other, national churches.
Martyr or Invader?
Authors: Choi Sangdo 
Published: November 2023

AbstractMartyr is the title given to someone who has died for the sake of their faith. However, the dead cannot speak about their own death. Judgments on behalf of the dead are inevitably done by the living, posthumously. In this sense, martyr‐making is the politics of the death operated by the living. Taking this perspective of martyr‐making, this paper seeks to reassess the martyr‐making process in the Protestant Church in Korea (PCK), focusing on the case of Rev. R. J. Thomas's death in Korea in 1866. Some argue that Thomas, with his original desire to be a missionary and his contribution in providing the Bible to native Koreans, is the first Protestant martyr in Korea. However, others contend, with the viewpoint of decolonization, that his approach, which appeared invasive, cannot be justified, even though he himself identified as a missionary. Even the ambiguity of his death prevents him from being called a martyr. Given that the process of martyr‐making or unmaking inevitably involves potential politicization by specific living authorities who interpret and designate individuals as martyrs, this paper explores the trends of martyr‐making in the PCK, where political and religious ideologies are deeply intertwined.
Decolonizing “Last Will Be First” and “Mission from the Margins”
Authors: Jagessar Michael N. 
Published: November 2023

AbstractThis contribution arose from the CWME's “decolonizing seminar” (5–9 June 2023), held in Lisbon on the theme “Making the last first.” Paying particular attention to mission archives and inherited missional‐theological deposits, this essay makes a case for decolonizing mission as both habit and method to create systemic change. Decolonizing of mission as a process is for the whole of the oikos and ecumenical family and is not only a Western Europe and former colonies matter, as coloniality and empires transcend periods, events, and locations.
Lesslie Newbigin's WCC Legacy
Authors: Behan Shawn P. 
Published: November 2023

AbstractFrom 1958 to 1965, J. E. Lesslie Newbigin worked for the International Missionary Council and then the World Council of Churches, specifically leading the integration of the organizations. Newbigin had a profound impact on the importance and role of mission within the ecumenical movement during the early transition of decolonialism around the globe. This article will reflect upon the history, contribution, and legacy of Newbigin in the conversation of mission in the ecumenical movement, specifically the World Council of Churches Commission on World Mission and Evangelism and the International Review of Mission. This reflection comes at the 25‐year mark since Newbigin's death and addresses part of Newbigin's legacy that recent books, The Church and Its Vocation and Becoming a Missionary Church, could only briefly discuss.
Freedom from Colonial Bondage
Authors: Pattel‐Gray Anne 
Published: November 2023

AbstractThis article sets out the colonial legacies and realities which continue to dominate indigenous peoples’ lives, experience, communities, and capacities in Australia. It roots this colonial violence in the particular efforts of missionaries to convert and dominate indigenous peoples with a white colonial God. The Bible was a key weapon for this work, but it is also central to the decolonial work of reconstruction and reparation. While Aboriginal Christians are rereading the biblical texts in ways that push back against the colonial occupation that is at the heart of the church's biblical exegesis, the article is pointing to this as a task laid on all churches and Christians, who can and should decolonize the dominant biblical and theological narratives. Further, there is a deep need to see theological education as a key location for reparation by the colonial inheritors, so that indigenous Christians can continue to deepen and deliver the tools that will help liberate mission and theological education from their colonial legacies.
Decolonizing Ourselves
Authors: Ekué Amélé Adamavi‐Aho 
Published: November 2023

AbstractThis article outlines some key steps and motifs for developing a decolonial relational ethics that will be vital not just to the work of decolonization but also to the practice of the ecumenical movement if it is to both add its weight to the calls for decolonization and itself be decolonized. The author interrogates key dimensions of her own field of study in Christian ethics and engagement in the ecumenical movement. She highlights some of the key spaces and often marginalized communities and persons who can shape the ecumenical movement's further engagement in decolonization. It offers a critique and a vision rooted in the author's lived experience and the scholarship of decolonization while seeking application in methodologies for colonial systems, relationships and mindsets to be challenged and reset.
Decolonizing Ableist Pedagogy
Authors: Novsima Isabella 
Published: November 2023

AbstractHow can someone born without a privileged language and not educated in a privileged educational institution engage in decolonization? This is a very relevant question for most people who live in the context of the global South. This paper proposes a constructive imagination to decolonize ableist pedagogy through feminist disability analysis. I argue that colonial pedagogy is inherently ableist. This paper is situated in an anti‐ableist and anti‐patriarchal framework, unveiling the normate culture and patriarchal‐colonial logic. However, the main source of analysis and epistemological tool is my body and experience as an Indonesian woman living with a disability. In trying to decolonize pedagogy, the experience of the body becomes more important than forming a new abstract theory of decoloniality. This paper proposes decolonizing ableist pedagogy as a communal work which requires examining colonial language and the binary thinking of body and mind through delinking the colonial space and crippling the colonial time. Based on this awareness, the decolonialization of ableist pedagogy is as imperative as the decolonialization of church mission.
Tracking severe acute respiratory syndrome coronavirus 2 transmission and co‐infection with other acute respiratory pathogens using a sentinel surveillance system in Rift Valley, Kenya
Authors: Ruttoh Vincent Kiplangat , Symekher Samwel Lifumo , Majanja Janet Masitsa , Opanda Silvanos Mukunzi , Chitechi Esther Wanguche , Wadegu Meshack , Tonui Ronald , Rotich Peter Kipkemboi , Nyandwaro Tonny Teya , Mwangi Anne Wanjiru , Mwangi Ibrahim Ndungu , Oira Robert Momanyi , Musimbi Audrey Gwazima , Nzou Samson Muuo 
Published: November 2023

AbstractBackgroundThe emergence of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) has been the most significant public health challenge in over a century. SARS‐CoV‐2 has infected over 765 million people worldwide, resulting in over 6.9 million deaths. This study aimed to detect community transmission of SARS‐CoV‐2 and monitor the co‐circulation of SARS‐CoV‐2 with other acute respiratory pathogens in Rift Valley, Kenya.MethodsWe conducted a cross‐sectional active sentinel surveillance for the SARS‐CoV‐2 virus among patients with acute respiratory infections at four sites in Rift Valley from January 2022 to December 2022. One thousand two hundred seventy‐one patients aged between 3 years and 98 years presenting with influenza‐like illness (ILI) were recruited into the study. Nasopharyngeal swab specimens from all study participants were screened using a reverse transcription‐quantitative polymerase chain reaction (RT‐qPCR) for SARS‐CoV‐2, influenza A, influenza B and respiratory syncytial virus (RSV).ResultsThe samples that tested positive for influenza A (n = 73) and RSV (n = 12) were subtyped, while SARS‐CoV‐2 (n = 177) positive samples were further screened for 12 viral and seven bacterial respiratory pathogens. We had a prevalence of 13.9% for SARS‐CoV‐2, 5.7% for influenza A, 2% for influenza B and 1% for RSV. Influenza A‐H1pdm09 and RSV B were the most dominant circulating subtypes of influenza A and RSV, respectively. The most common co‐infecting pathogens were Streptococcus pneumoniae (n = 29) and Haemophilus influenzae (n = 19), accounting for 16.4% and 10.7% of all the SARS‐CoV‐2 positive samples.ConclusionsAugmenting syndromic testing in acute respiratory infections (ARIs) surveillance is crucial to inform evidence‐based clinical and public health interventions.
Reaction kinetics and microstructure of pegmatite‐based geopolymer composites: influence of calcined clay nature
Authors: Nana Achile , Alomayri Thamer , Tome Sylvain , Nath Susanta , Kamseu Elie , Bignozzi Maria Chiara , Leonelli Cristina , Kumar Sanjay 
Published: November 2023

AbstractThis research reports the investigations of threshold reactivity limit of blends of pegmatite with different calcined clays as well as the influence of calcined clay source on the geopolymerization kinetic, microstructural, and physico‐mechanical properties of feldspathic mineral‐based inorganic polymer composites. These composites were designed from 85 to 94 wt% of the solid solution of pegmatite and calcined clay. The three‐point flexural and compressive strengths, porosity, and microstructure as well as heat evolution rate of geopolymerization reactions of resulting composites were affected by the type of calcined clay. The four calcined clays provided the highest mechanical properties of the composites when added in the range of 12–15 wt%. Specifically, the values of flexural and compressive strengths ranged from 32 to 34 MPa and 101 to 105 MPa, respectively, for geopolymer composites with 15 wt% of metakolin added, while they ranged from 38 to 42 MPa and 106 to 107 MPa with 12 wt% of meta‐hallosyte added. The polycondensation/polymerization process of calcined clay developed sufficient amounts of N‐A‐S‐H and polysialate geopolymer to cover the incongruently dissolved fine particles of pegmatite. The resulting microstructure was dense and compact with the lower cumulative pore volume at about 91 mm3/g. It was concluded that designing the pegmatite/clay‐based geopolymer composites with high mechanical strengths and low porosity resulted in sustainable, low energy consumption and environmental‐friendly materials for civil engineering.
The association of social support and hope with self‐stigma and perceived recovery among people with schizophrenia: The serial mediation effect
Authors: Huang Li Ting , Liu Ya Ling , Pao Che Hao , Chang Yu Ho , Chu Ru Ying , Hsu Hui Min , Wei Dia Ru , Yang Chiu Yueh 
Published: November 2023

AbstractBackgroundIt is essential to assist individuals with a mental illness who have achieved clinical recovery in their personal recovery. Understanding the relationship between self‐stigma and social support and the effects on perceived recovery can be valuable for clinical professionals in helping patients lead meaningful lives.AimTo examine the serial mediating roles of social support and perceived hope in self‐stigma and the effects on perceived recovery.DesignA cross‐sectional study.MethodsThe study was conducted from September 2019 to June 2020. One hundred and fifty‐seven patients with schizophrenia in seven chronic rehabilitation wards were enrolled. Each patient had a Positive and Negative Syndrome Scale score ≤ 60 points, and they regularly participated in occupational rehabilitation. Research tools included demographic data, the Internalized Stigma of Mental Illness Scale (ISMIS), Multidimensional Scale of Perceived Social Support (MSPSS), Herth Hope Index (HHI), and Perceived Recovery Inventory (PRI). IBM SPSS 24.0 was used to analyse the data. Pearson correlation was used to analyse the relationships between variables, and models 4 and 6 of PROCESS macro V3.4 for SPSS were used to examine the mediation model.ResultsThe results indicated that self‐stigma and perceived recovery in patients with schizophrenia are negatively correlated, that peer support and perceived hope mediate the relationship between them, and that peer support and perceived hope also have a statistically significant serial mediating effect.ConclusionThe serial mediation effect of peer support and perceived hope on the relationship between self‐stigma and perceived recovery was statistically significant in this study.ImpactThis research delves into strategies to assist psychiatric patients in reducing self‐stigma and achieving recovery. The findings underscore the heightened significance of peer support for patients in rehabilitative wards and offer valuable insights for medical staff.Reporting MethodSTROBE checklist.Patient or Public ContributionNo patient or public contribution.