bluuebunny/crossref_metadata_2025_split huggingface dataset:
Psycho-linguistic and educational challenges in Teaching Chinese (Mandarin) Language: voices from None-Chinese teachers of Mandarin language
Authors: Pan Lei , Sun Dan , Zou Yumei , Cao Yi , Zhang Jingxian , Li Fangfang 
Published: November 2023

Abstract
Background
Chinese/Mandarin language instruction to undergraduate students from non-Chinese speaking countries has become a topic of increasing interest, driven by China’s influential role in global political and economic dynamics. With Mandarin being the language spoken by approximately 70% of Chinese speakers, it is not only taught within China but also in institutions around the world. While teaching any second or foreign language presents unique challenges, the specific challenges faced in Mandarin language education have not received comprehensive scrutiny, prompting the need for further investigation.

Objectives
The primary objective of this study was to explore the challenges associated with teaching and learning Mandarin from the perspectives of non-native Mandarin language teachers. By adopting a qualitative (phenomenological) research approach, we aimed to uncover the multifaceted challenges that confront both educators and learners in the context of Mandarin language instruction.

Methodology
The research methodology employed for this study involved the use of semi-structured interviews conducted with 15 Mandarin language teachers, who were chosen through theoretical sampling. These interviews were transcribed into text files and subsequently subjected to qualitative data analysis, which was facilitated by the use of MAQDA software. This approach allowed us to identify and categorize the various challenges and problems encountered in the teaching and learning of Mandarin.

Findings
The research findings revealed a range of challenges and problems experienced in Mandarin language education. These challenges were grouped into two primary thematic categories: psycho-linguistic and educational challenges. The linguistic challenges are deeply rooted in the distinctive features of the Mandarin language, presenting obstacles that necessitate innovative teaching strategies and materials. Educational challenges extend beyond native speaker proficiency, emphasizing the requirement for a comprehensive pedagogical skill set among instructors.

Implications
: The implications of this research extend to various stakeholders in the field of Chinese/Mandarin language education, including policymakers, educators, curriculum designers, and learners. Understanding the linguistic, educational, and psychological challenges can inform the development of more effective teaching methods, curriculum design, and motivation-enhancing strategies, ultimately promoting a more successful and engaging Mandarin language learning experience for non-native speakers.
Prediction of earth pressure balance for EPB-TBM using machine learning algorithms
Authors: Samadi Hanan , Hassanpour Jafar , Rostami Jamal 
Published: November 2023

AbstractFace stability control of excavation with earth pressure balance machine (EPB) approach is the best available method to reduce the ground deformation and settlement of surface structures in a tunneling project in urban areas. In the present paper, several models have proposed through a statistical method, including feed-forward stepwise regression (FSR) and machine learning techniques such as support vector machine (SVM), Takagi–Sugeno fuzzy model (TS), and multilayer perceptron neural network (ANN-MLP), to provide a predictive strategy for EPB machine during the tunnel excavation. For this purpose, a monitoring dataset of machine performance parameters including advance speed, screw conveyor speed, screw conveyor torque, thrust force, and cutterhead rotation speed from Tehran Metro Line 6 Southern Extension Sector (TML6-SE) has been compiled. Then, the relation between the performance parameters and target values were investigated to analyze the available inputs and offer a new equation using the FSR. Moreover, evaluation metrics and loss functions were utilized for the evaluation of the developed models’ efficiency. The results proved the significance of the presented methods in this paper that could be used to predict the earth pressure balance operation with high efficiency.
Identification of native entomopathogenic fungi associated with Mahanarva fimbriolata Stahl in silvopastoral systems (Urochloa brizantha cv. MG-5 and Eucalyptus spp.)
Authors: Sarubbi H. , Resquín-Romero G. , Garrido-Jurado I. 
Published: November 2023

Abstract
Background
Pastures are susceptible to attacks from various species of insects, with Cercopidae being one of the main responsible pests. The species Mahanarva fimbriolata has a wide distribution in the Eastern region of Paraguay, leading to pasture damage. The most promising alternatives to chemical use are bioinsecticides, which could offer effective control while minimizing negative environmental impacts. Beauveria and Metarhizium have been documented as biocontrol fungi for Cercopidae insects. Therefore, identifying and isolating virulent native strains presents potential alternatives for controlling the spittlebug M. fimbriolata.

Results
Based on morphological and molecular characteristics, native strains of Metarhizium anisopliae and Beauveria bassiana were identified in the collected insects. Phylogenetic trees confirmed that the Beauveria sequence (Beauveria seq) obtained in this study aligned with the ARSEF 842 isolate of B. bassiana. The Metarhizium sequence (Metarhizium seq) was in the same clade as ARSEF 7450 and ARSEF 7487, which belong to the Metarhizium anisopliae. Beauveria bassiana displayed conidiophores that were broad at the basal part, forming synnemata or groups of conidiophores closely packed together, with a typical "zig-zag"-shaped rachis. The conidia were hyaline and smooth, ellipsoidal, and globose. On the other hand, M. anisopliae exhibited simple, straight conidiophores with bottle-shaped phialides. The conidia were elongated, ovoid to cylindrical, arranged in chains, and had an olive green color.

Conclusions
This is the first report of Metarhizium anisopliae and Beauveria bassiana obtained from nymphs and adults of Mahanarva fimbriolata in Paraguay.
Alagille syndrome and liver: an adult case report
Authors: Kharmach Oussama , Borahma Mohamed , Ajana Fatima-Zohra 
Published: November 2023

Abstract
Background
Alagille syndrome is a rare autosomal-dominant disorder, representing 10 to 15% of the causes of neonatal cholestasis with no gender predominance. The diagnosis is based on the association of liver, heart, eye, skeleton abnormalities, and characteristic facial appearance.

Case presentation
An 18-year-old male patient, with a family history of benign recurrent intrahepatic cholestasis in a brother, was diagnosed at birth with bile duct paucity. He consulted in adulthood for cholestatic jaundice and pruritus. Physical exam found cutaneous jaundice, particular face, skeletal abnormality of fingers, posterior embryotoxon, and splenomegaly. An echocardiogram found cardiovascular abnormalities. The diagnosis of Alagille syndrome was made in front of five major criteria. A liver biopsy revealed a cirrhosis liver. Upper gastrointestinal endoscopy revealed grade II esophageal varices of portal hypertension. Laboratory tests revealed bicytopenia related to hypersplenism, hypoferritinemia, cytolysis with cholestasis, high bilirubin levels, low prothrombin time, hypoalbuminemia, decreased factor V activity, and hypocholesterolemia. The patient had vitamin K supplementation and was put on ursodeoxycholic acid, propranolol for the liver disease, a high protein hypercaloric diet for malnutrition, vitamin D supplementation and bisphosphonate for the osteoporosis, therapeutic abstention with monitoring for the asymptomatic cardiac disease. After a year of treatment, the patient had an overall health status improvement. Abdominal ultrasound found liver nodules. A biliary MRI showed a multinodular liver. The complement by CT hepatic angiography did not show any nodules while the MRI angiography revealed multiple dysplastic nodules. A liver biopsy was performed and found regenerative nodules.

Conclusion
The treatment of Alagille syndrome is based on managing the cholestasis and its complications, especially pruritus because it can have a significant impact on quality of life. Due to the complexity of presentation and multi-organ involvement, management of cases with Alagille syndrome should be done by a multidisciplinary team. Liver disease is responsible for morbidity while cardiac disease is a mortality risk factor in this population.
Variable cross-sectional effect on bi-directional blades–tower–soil–structure dynamic interaction on offshore wind turbine subject to wind–wave loads
Authors: El Absawy Mostafa A. , Elnaggar Zakaria , Ibrahim Hesham H. , Taha M. H. 
Published: November 2023

Abstract
Background
This study introduces a numerical model designed to simulate interactions occurring between a wind turbine's tower and the surrounding soil, as well as between the nacelle, blades, and the surrounding environment. This simulation accounts for both fore–aft and side-to-side movements. To describe these interactions, the model leverages the Euler–Lagrange equations. It calculates wave loads utilizing the Morison equation, with wave data generated based on the JONSWAP spectrum. Furthermore, aerodynamic loads are determined using the blade element moment theory, and the wind spectrum is generated using the Von Karman turbulence model. The tower is represented as a variable cross-sectional beam, employing a two-noded Euler beam element with two degrees of freedom: transverse displacement and rotation, and utilizing Hermite polynomial shape functions.

Results
In a comparative analysis against experimental data, this modified model demonstrates significant enhancements in accurately reproducing the dynamic behavior of wind turbines with variable cross-sectional towers, outperforming models that approximate the tower with a constant cross section. Our findings reveal that the modified model achieves a remarkable improvement of 15% in replicating the tower's dynamic response when compared to the constant cross-sectional models. As a case study, a 5 MW monopile wind turbine with a flexible foundation, specifically the one provided by the National Renewable Energy Laboratory (NREL), is employed to simulate its dynamic response.

Conclusions
This research presents a robust numerical model for simulating wind turbine behavior in various environmental conditions. The incorporation of variable cross-sectional tower representation significantly improves the model's accuracy, making it a valuable tool for assessing wind turbine dynamics. The study's findings highlight the importance of considering tower flexibility in wind turbine simulations to enhance their real-world applicability.
Progesterone Activates the Histone Lactylation–Hif1α-glycolysis Feedback Loop to Promote Decidualization
Authors: Zhao Wei , Wang Yue , Liu Juan , Yang Qianying , Zhang Shuai , Hu Xiao , Shi Zhicheng , Zhang Zhenni , Tian Jianhui , Chu Dapeng , An Lei 
Published: November 2023

Abstract
Decidualization is a progesterone-dependent cellular differentiation process that is essential for establishing pregnancy. Robust activation of glycolysis and lactate synthesis during decidualization is remarkable, but their developmental functions remain largely unknown. Herein, we identify that endometrial lactate production plays a critical role in establishing local histone lactylation, a newly identified histone modification, and is important for ensuring normal decidualization. Enhanced endometrial glycolysis is the hallmark metabolic change and is tightly coupled with H4K12la during decidualization. Inhibition of histone lactylation impaired decidualization, in either physiological conception or in vivo and in vitro induced decidualization models. Mechanistic study based on CUT&Tag and ATAC-seq revealed that a transcriptional factor hypoxia-inducible factor 1 α (Hif1α) is the critical regulatory target of H4K12la, and in turn forms an H4K12la–Hif1α-glycolysis feedback loop to drive decidualization. Moreover, we demonstrate that the loop is directly activated by progesterone during decidualization. Our study not only advances the current knowledge of the role of lactate in regulating uterine function, but also establishes a novel functional link among the major endocrine factors, endometrial metabolic change, and epigenetic modification during endometrial remodeling. These findings present valuable clues to develop clinical intervention strategies to improve pregnancy outcomes following both natural conception and assisted reproduction.
A top-secret game: metadiscourse analysis of the contractual discourse of purchasing 100 shares of the Suez Canal Company in 1947
Authors: El-Falaky May S. 
Published: November 2023

Abstract
This paper examines categories and functions of interactive and interactional textual elements used in the contractual discourse of selling/purchasing 100 shares of the Suez Canal Company in 1947. The exchanged documents between the involved parties, the Egyptian (buyer) and the American (seller), are analyzed using Metadiscourse Analysis (MDA) as an approach to analyzing the textual resources used in the selected corpus. Game Theory is also used in conjunction with MDA to allocate the strategic behaviors of the players within the competitive contextual surroundings of the selected discourse. The analysis explains the structural constructions of the correspondences exploring how interactional relations between the participants are linguistically crafted. The analysis of the contract discourse is argued to contribute to econo-linguistics by examining how MDA and Game Theory can be integrated to construe/construct discourses about economics. The article concludes that metadiscourse resources enable the discourse of contracts to maintain a dialogic interactional language between the seller and the buyer. This interaction assimilates a game where the author and the reader (or players) exchange moves strategically to reach the target payoff. Thus, it can be argued that integrating MDA and Game Theory benefits econo-linguistics in highlighting hidden agendas and understanding interactive and interactional meanings in the discourse.
Real-world practice of idiopathic pulmonary fibrosis: Results from a 2000–2016 cohort
Authors: Wang Ying-Tso , Shen Te-Chun , Lin Cheng-Li , Tu Chih-Yen , Hsia Te-Chun , Hsu Wu-Huei 
Published: November 2023

Abstract
The study aimed to investigate comorbidities, major adverse respiratory events, and mortality in patients with idiopathic pulmonary fibrosis (IPF). We established an IPF cohort and a comparative cohort matched for sex, age, and the date of IPF diagnosis. We recorded the most frequent comorbidities, the proportions, and time durations to the episode of major adverse respiratory events and death. Both cohorts were followed up to the end of 2016. We included 921 patients in the IPF cohort and 3,677 individuals in the comparative cohort. Comorbidities associated with IPF included pulmonary hypertension, chronic obstructive pulmonary disease, heart failure, asthma, and gastroesophageal reflux disease. The IPF cohort was more likely to have pneumonia (47.6 vs 12.0%), acute respiratory failure (17.8 vs 4.30%), chronic respiratory failure (4.23 vs 0.63%), and death (36.3 vs 15.0%) than the comparative cohort. The time durations to the first episode of pneumonia, acute respiratory failure, chronic respiratory failure, and death were 2.09 ± 2.98, 3.12 ± 3.62, 3.20 ± 4.03, and 3.27 ± 3.03 years in the IPF cohort. In conclusion, patients with IPF had significant comorbidities, particularly pulmonary and cardiovascular comorbidities. The duration from diagnosis to the major adverse respiratory events or death was short.
Mathematical analysis of an epidemic model with direct and indirect transmission modes and two delays
Authors: Najm Fatiha , Yafia Radouane , Alaoui My Ahmed Aziz , Tridane Abdessamad , Boukrim Lahcen 
Published: November 2023

Abstract
In this article, we consider an epidemiological model in which we take into account the effects of direct and indirect transmissions. The first mode occurs through direct contact between infectious and susceptible individuals, and the second one will take place through the shedding of virus particles by infectious individuals and their acquisition by susceptible ones. We also study the effect of latency period and time needed for a susceptible person to become infected by indirect transmission mode. By considering the direct and indirect basic reproduction numbers, we define the basic reproduction number

R

0

{R}_{0}

of the model, which helps us to analyze the stability of equilibria and bifurcation and determine the most sensitive parameters. In conclusion, some numerical simulations are given to confirm the analytical analysis.
From Abrogation to Dominion: Navigating India’s Neo-Colonial Settler Agenda in Kashmir and Elimination of Kashmiri Identity
Authors: Hussain Mehmood 
Published: November 2023

Abstract
This paper examines the neo-colonial project of Narendra Modi implemented in Kashmir after the revocation of special status on August 5, 2019. The neo-colonial infrastructure supported by the threads of re-classification of legal residents and land designations intends to significantly transform the demography of Muslim majority Kashmir into a Muslim minority, consequently destroying the Muslim identity of the state. The abrogation of Article 370 and enactment of new domicile law has extended the legal and administrative control of New Delhi, making Kashmir indistinguishable from the Indian legal system and leaving no room for the local legislative assembly to make laws beneficial for the state residents. The paper asks how India is implementing the neo-colonial settler agenda in Kashmir. How and to what extent legal and military instruments are employed to disempower Kashmiris from territorial and cultural identity? The paper argues that Prime Minister Narendra Modi is pursuing a neo-colonial settler agenda in Kashmir through ‘destroy and replace,’ which is supported by the neo-liberal agenda, including; new land management policy, new domicile law, spatial planning and development, new settlements of Hindus, authoritative central control, and massive militarization to carry out gross human rights abuses and repression.
Comparative investigations of Ag/H2O nanofluid and Ag-CuO/H2O hybrid nanofluid with Darcy-Forchheimer flow over a curved surface
Authors: Lu Wenjie , Farooq Umar , Imran Muhammad , Chammam Wathek , El Din Sayed M. , Akgül Ali 
Published: November 2023

Abstract
Nanofluid performed well and produced good results in heat transport phenomena, attracting scientists to suspend other combinations of nanoparticles, called “hybrid nanofluid. Hybrid nanofluids are superior than nanofluids due to their thermal capabilities and emerging benefits that contribute to the boost in the rate of heat transmission. Applications for these nanoparticles, including sophisticated lubricants, are increasing in the fields of bioengineering and electricity. The main prospective of this research is to inquire about the water-based dual nature nanofluid stream numerical simulation through the irregular stretched sheet with heat transfer. In this perspective, silver with base fluid water is used as nanoparticles for nanofluid, and for making hybrid nanofluid, copper oxide and silver particles are used with water-based fluid. Modified Fourier and Fick’s model for heat flux utilized the above phenomenon and observed the heat and mass transport. Similarity variables are needed to transform the partial differential equations into associated nonlinear ordinary differential equations, which are then computationally resolved by the technique of bvp4c which is a built-in function in MATLAB mathematical software. Based on the concurrent approximations, reformations are performed to determine the impact of various quantities on flow variables. The predicted outcomes are depicted in velocity, temperature, and concentration profiles through graphical depiction. The factors indicate that the hybrid nanofluid is more powerful in the transfer of heat than a basic nanofluid because of its superior thermal characteristics. The velocity profile decays for the increasing values of Darcy-Forchheimer parameter. The thermal profile increases for the higher magnitude of Darcy-Forchheimer parameter. The velocity distribution profile increases for the higher values of curvature parameter, while the thermal profile decreases. This unique work might benefit nanotechnology and related nanocomponents. This safe size-controlled biosynthesis of Ag and CuO nanoparticles has resulted in a low-cost nanotechnology that may be used in a variety of applications. Biosynthesized Ag and CuO particles have been used successfully in a variety of applications, including biomedical, antibacterial agents, biological, food safety, and biosensing, to mention a few.
Silver, copper, and cobalt trimetallic nanoparticles; synthesis, characterization and its application as adsorbent for acid blue 7 dye
Authors: Alam Sultan , Ullah Shakir , Ilyas Muhammad , Rehman Najeeb Ur , Zahoor Muhammad , Umar Muhammad Naveed , Ullah Riaz , Ali Essam A. 
Published: November 2023

Abstract
The synergistic effects of metal complex nanoparticles in remediation of environment had opened a versatile field of research as providing differential attractive forces for a given pollutant on their surfaces. Herein, trimetallic nanoparticles of silver, copper and cobalt (Ag–Cu–Co TNPs) were prepared via chemical reduction method using sodium borohydride as reductant which were then characterized through SEM, EDX, XRD and FT-IR analytical techniques. As model dye, acid blue 7 was adsorbed on the surface of fabricated particles utilizing batch adsorption approach. The adsorption conditions like temperature, adsorbent dosage, pH, and contact time were optimized to get maximum adsorption of the selected dye which were; 333 K, 0.01 g, pH 6 and 30 min respectively. The adsorption data were analyzed using kinetic and isotherm models, with the linear pseudo 2nd order kinetics and Langmuir models being the most suitable. The maximum adsorption capacity at 333 K was found to be 74.07 mg/g. Thermodynamic variables such as entropy (ΔS°), enthalpy (ΔH°), and Gibbs free energy (ΔG°) changes were calculated to understand the adsorption feasibilities. Results indicated that the adsorption process was endothermic (ΔH° = 6.867 KJ mol−1) and spontaneous ΔG° (J mol−1) −219.2, −702.9 and −1086.6 at 293 K, 313 K and 333 K respectively. The entropy change (ΔS° = 24.185 J mol−1 K−1) suggested an increased disorder at the solid–solution interface during adsorption.