bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does Laterality in Breast Cancer still have the Importance to be
Studied? A Meta-analysis of Patients with Breast Cancer
Authors: Zheng Xiao , Xu Cong , Ganesan Kumar , Chen Haiyong , Cheung Yuen Shan , Chen Jianping 
Published: November 2023

Background:
Breast cancer (BC) is one of the most common cancers in the
world. Studies show that left-sided BC in pre and post-menopausal women leads to double
the risk of worse morbidity and mortality and the reasons are uncertain. Finding the
relationship between BC laterality and other possible risk factors can be advantageous
for the prognosis of BC.

Objective:
This present study aimed to analyze the relationship between BC laterality
and possible risk factors.

Methods:
A total of 6089 studies were screened. 23 studies from 1971 to 2021 met the
inclusion criteria and were included in the meta-analysis. A pooled relative risk was generated
via meta-analysis with a 95% confidence interval

Results:
Left-side BC laterality was significant (p < 0.00001) in the women populations
compared to the right side based on the pooled size with possible high-risk factors, including
handedness, older women, body mass index, people with black skin, invasive
type carcinoma, and estrogen receptor-negative BC. These findings suggest that there
may be a complex interplay of genetic, environmental, and lifestyle factors that contribute
to left-side BC laterality.

Conclusion:
Results suggest an increased rate of BC on the left side, with high-risk factors
contributing to BC laterality, which may be useful in predicting prognosis. This
study provides significant insights into the relationship between high-risk factors and
BC laterality. By identifying potential risk factors associated with left-side BC, it may
be possible to improve the ability to predict prognosis and develop more targeted treatment
strategies. This information could be particularly useful for healthcare providers
and patients, as it may guide decisions regarding screening, prevention, and treatment,
ultimately improving patient outcomes and reducing the overall burden of BC.
User-Guided Enhancements to a Technology-Facilitated Resilience Program to Address Opioid Risks Following Traumatic Injury in Youth: Qualitative Interview Study
Authors: Adams Zachary W , Marriott Brigid R , Karra Swathi , Linhart-Musikant Elizabeth , Raymond Jodi L , Fischer Lydia J , Bixler Kristina A , Bell Teresa M , Bryan Eric A , Hulvershorn Leslie A 
Published: November 2023

Background
Youth with traumatic injury experience elevated risk for behavioral health disorders, yet posthospital monitoring of patients’ behavioral health is rare. The Telehealth Resilience and Recovery Program (TRRP), a technology-facilitated and stepped access-to-care program initiated in hospitals and designed to be integrated seamlessly into trauma center operations, is a program that can potentially address this treatment gap. However, the TRRP was originally developed to address this gap for mental health recovery but not substance use. Given the high rates of substance and opioid use disorders among youth with traumatic injury, there is a need to monitor substance use and related symptoms alongside other mental health concerns.

Objective
This study aimed to use an iterative, user-guided approach to inform substance use adaptations to TRRP content and procedures.

Methods
We conducted individual semistructured interviews with adolescents (aged 12-17 years) and young adults (aged 18-25 years) who were recently discharged from trauma centers (n=20) and health care providers from two level 1 trauma centers (n=15). Interviews inquired about reactions to and recommendations for expanding TRRP content, features, and functionality; factors related to TRRP implementation and acceptability; and current strategies for monitoring patients’ postinjury physical and emotional recovery and opioid and substance use. Interview responses were transcribed and analyzed using thematic analysis to guide new TRRP substance use content and procedures.

Results
Themes identified in interviews included gaps in care, task automation, user personalization, privacy concerns, and in-person preferences. Based on these results, a multimedia, web-based mobile education app was developed that included 8 discrete interactive education modules and 6 videos on opioid use disorder, and TRRP procedures were adapted to target opioid and other substance use disorder risk. Substance use adaptations included the development of a set of SMS text messaging–delivered questions that monitor both mental health symptoms and substance use and related symptoms (eg, pain and sleep) and the identification of validated mental health and substance use screening tools to monitor patients’ behavioral health in the months after discharge.

Conclusions
Patients and health care providers found the TRRP and its expansion to address substance use acceptable. This iterative, user-guided approach yielded novel content and procedures that will be evaluated in a future trial.
The Alzheimer’s Knowledge Base: A Knowledge Graph for Alzheimer Disease Research
Authors: Romano Joseph D , Truong Van , Kumar Rachit , Venkatesan Mythreye , Graham Britney E , Hao Yun , Matsumoto Nick , Li Xi , Wang Zhiping , Ritchie Marylyn D , Shen Li , Moore Jason H 
Published: November 2023

Background
As global populations age and become susceptible to neurodegenerative illnesses, new therapies for Alzheimer disease (AD) are urgently needed. Existing data resources for drug discovery and repurposing fail to capture relationships central to the disease’s etiology and response to drugs.

Objective
We designed the Alzheimer’s Knowledge Base (AlzKB) to alleviate this need by providing a comprehensive knowledge representation of AD etiology and candidate therapeutics.

Methods
We designed the AlzKB as a large, heterogeneous graph knowledge base assembled using 22 diverse external data sources describing biological and pharmaceutical entities at different levels of organization (eg, chemicals, genes, anatomy, and diseases). AlzKB uses a Web Ontology Language 2 ontology to enforce semantic consistency and allow for ontological inference. We provide a public version of AlzKB and allow users to run and modify local versions of the knowledge base.

Results
AlzKB is freely available on the web and currently contains 118,902 entities with 1,309,527 relationships between those entities. To demonstrate its value, we used graph data science and machine learning to (1) propose new therapeutic targets based on similarities of AD to Parkinson disease and (2) repurpose existing drugs that may treat AD. For each use case, AlzKB recovers known therapeutic associations while proposing biologically plausible new ones.

Conclusions
AlzKB is a new, publicly available knowledge resource that enables researchers to discover complex translational associations for AD drug discovery. Through 2 use cases, we show that it is a valuable tool for proposing novel therapeutic hypotheses based on public biomedical knowledge.
Predictors of Use and Drop Out From a Web-Based Cognitive Behavioral Therapy Program and Health Community for Depression and Anxiety in Primary Care Patients: Secondary Analysis of a Randomized Controlled Trial
Authors: Rotondi Armando J , Belnap Bea Herbeck , Rothenberger Scott , Feldman Robert , Hanusa Barbara , Rollman Bruce L 
Published: November 2023

Background
A previously reported study examined the treatment of primary care patients with at least moderate severity depressive or anxiety symptoms via an evidence-based computerized cognitive behavioral therapy (CCBT) program (Beating the Blues) and an online health community (OHC) that included a moderated internet support group. The 2 treatment arms proved to be equally successful at 6-month follow-up.

Objective
Although highly promising, e-mental health treatment programs have encountered high rates of noninitiation, poor adherence, and discontinuation. Identifying ways to counter these tendencies is critical for their success. To further explore these issues, this study identified the primary care patient characteristics that increased the chances patients would not initiate the use of an intervention, (ie, not try it even once), initiate use, and go on to discontinue or continue to use an intervention.

Methods
The study had 3 arms: one received access to CCBT (n=301); another received CCBT plus OHC (n=302), which included a moderated internet support group; and the third received usual care (n=101). Participants in the 2 active intervention arms of the study were grouped together for analyses of CCBT use (n=603) because both arms had access to CCBT, and there were no differences in outcomes between the 2 arms. Analyses of OHC use were based on 302 participants who were randomized to that arm.

Results
Several baseline patient characteristics were associated with failure to initiate the use of CCBT, including having worse physical health (measured by the Short Form Health Survey Physical Components Score, P=.01), more interference from pain (by the Patient-Reported Outcomes Measurement Information System Pain Interference score, P=.048), less formal education (P=.02), and being African American or another US minority group (P=.006). Characteristics associated with failure to initiate use of the OHC were better mental health (by the Short Form Health Survey Mental Components Score, P=.04), lower use of the internet (P=.005), and less formal education (P=.001). Those who initiated the use of the CCBT program but went on to complete less of the program had less formal education (P=.01) and lower severity of anxiety symptoms (P=.03).

Conclusions
This study found that several patient characteristics predicted whether a patient was likely to not initiate use or discontinue the use of CCBT or OHC. These findings have clear implications for actionable areas that can be targeted during initial and ongoing engagement activities designed to increase patient buy-in, as well as increase subsequent use and the resulting success of eHealth programs.

Trial Registration
ClinicalTrials.gov NCT01482806; https://clinicaltrials.gov/study/NCT01482806
PENGARUH SOCIAL MEDIA MARKETING TERHADAP BRAND AWARENESS DAN PURCHASE INTENTION KONSUMEN BRAND SKINCARE AVOSKIN DI KOTA BANDUNG
Authors: Pahlevi Aqshel Reza , Trianasari Nurvita 
Published: November 2023

Abstract: The post-modern business era has provided many opportunities such as social media and offers many challenges to business sustainability. Covering almost all age groups and different regions, the use of social media makes this digital platform a way to showcase a brand. To build its brand, Avoskin uses various digital platforms, such as social networks, websites and e-commerce. Social media marketing can influence consumer interests, interests, decisions, in choosing products or services, consumers choose products that are familiar or suitable. This research examines the influence of social media marketing on brand awareness and purchase intention of consumers of the Avoskin skincare brand in Bandung. The object of this research is consumers of the Avoskin skincare brand in Bandung. The method used in this research is quantitative with a Structural Equation Modeling (SEM) approach with a PLS approach with the help of data processing software SmrtPLS 4.0. Data collection uses an online questionnaire.Keywords: Social Media Marketing; Brand Awareness; Purchase Intention.Abstrak: Era bisnis pasca modern telah memberikan banyak peluang seperti adanya sosial media dan menawarkan banyak tantangan pada keberlanjutan bisnis. Mencakup hampir semua kelompok umur dan wilayah yang berbeda, penggunaan media sosial menjadikan platform digital ini sebagai cara untuk memamerkan sebuah brand. Untuk membangun mereknya, Avoskin menggunakan berbagai platform digital, seperti jejaring sosial, website, dan e-commerce. Social media marketing dapat mempengaruhi minat, ketertarikan, keputusan konsumen, dalam memilih produk atau jasa, konsumen memilih produk yang familiar atau cocok. Penelitian ini menguji pengaruh social media marketing terhadap brand awareness dan purchase intention konsumen brand skincare Avoskin di Bandung. Objek penelitian ini adalah konsumen brand skincare Avoskin di Bandung. Metode yang digunakan dalam penelitian ini adalah kuantitatif dengan pendekatan Structural Equation Modeling (SEM) dengan pendekatan PLS dengan bantuan pengolahan data software SmrtPLS 4.0. Pengambilan data menggunakan kuesioner online.Kata Kunci: Social Media Marketing; Brand Awareness; Purchase Intention.
Rice Fallow No-Till Sorghum Using Inorganic Fertilizers in Combination with Biofertilizer Consortium: Nutrient Uptake, Yield Attributes and Economics
Authors: Reddy Kadapa Sreenivasa , Rao Ch. Pulla , Luther M. Martin , Prasad P. R. K. 
Published: November 2023

A field investigation was carried out to study the influence of inorganic fertilizers along with biofertilizer consortium on the performance of sorghum under rice fallows at Agricultural College Farm, Bapatla, Acharya N. G. Ranga Agricultural University, Andhra Pradesh, India during rabi (December–April), 2018–19. There were 7 treatments tested in randomized block design (RBD) with 3 replications. Yield attributes, length of earhead (33.2 cm), number of filled grains earhead-1 (1359) and maximum protein content (9.1) were recorded higher in 125% RDF+biofertilizer consortium and remained significantly on par with 100% RDF+biofertilzers consortium treatment. Application of 125% RDF+ biofertilizer consortium application (T6) significantly increased grain and stover yields by (30.3%, 26.5%) respectively, compared to control. The same T6 treatment recorded highest nitrogen, phosphorus and potassium uptake at 30, 60, 90 DAS and at harvest in the grain and straw followed by T5 treatment. Significantly higher grain, stover, and biological yield were obtained with 125% RDF treatment compared to 75% and 50% RDF. Improvement in N, P and K uptake in grain by (53.0, 58.0 and 74.4%) and stover by (50.5, 51.8 and 50.1%) compared with control treatment. The highest gross returns (Rs. ` 71710 ha-1), net returns (`Rs. 43155 ha-1) and returns `-1 investment (1.88) was obtained with application of 125% RDF+Biofertilizer consortium treatment. When compared to other treatments, the use of 125% RDF+Biofertilizer consortium increased the production and provided economic benefits may be adapted as choice of viable alternative in the coastal Andhra Pradesh.
Video-based Analysis for Teacher Development in Physical Education
Authors: Constantinides Panos 
Published: November 2023

The world in the 21st century is a world of technology and revolution in different aspects of life. The increasing desire of young people to use technology (van Laarhoven & van Laarhoven-Myers, 2006) at home, at work, and during leisure time has made industry come up with a variety of tools to be used. In such a scenario, the video recording analysis method has become a helpful tool in researchers’ and educators’ hands, allowing them to observe and assess a class, conduct pedagogy research, and so forth. For some time, video has been used to record and analyze human movement for health issues. Physical education professionals and coaches took advantage of technology to improve their athletes’ performance using video capture. The video gave them the opportunity to analyze and inform their athletes for better performance during competition. Video-based observation has been used in several studies conducted in schools, for different disciplines and for different reasons, such as to compare different teaching styles, to compare teaching behaviors of teachers, to compare student participation in class, or teaching effectiveness (Constantinides et al., 2013). In physical education, there is a growing interest among physical educators to incorporate digital technology in their teaching (Pyle & Esslinger, 2014; Thomas & Stratton, 2006). In this paper, however, the focus of the discussion is on how this technology may help the teacher develop and provide more effective lessons to the students. Therefore, the process of video recording is analyzed, the value-based observation is thoroughly discussed, as well as the value for the teacher who wants to develop his teaching. Furthermore, suggestions are made for physical education teachers who may use this method in the future for their own development in teaching physical education.
Jáchymov: Borders of Oblivion
Authors: Kulmiński Robert 
Published: November 2023

Abstract
The remarkably dynamic history of the small Czech town of Jáchymov provides the possibility of tracing memory, forgetting and recalling through constant rewriting and negotiation – both of a place of the individual memories, as well as the hierarchy of the events which are worthy of being remembered, and those that would rather be forgotten. German, Soviet, and Czech presence here cross with the spa and military nature of this place and its martyrological memory, on one side of the transfer of the German population shortly after World War II, and on the other one the political prisoners of the 1950s, who were forced into slave labor in the local uranium mine. All of these layers still remain today – referring to the title of the book by Karolina Ćwiek-Rogalska – remembered in Jáchymov's summer landscape, in which the air is breaking the image of reality, making it fluid, and somewhat elusive. And it is this variety of the layers of memory, recalling, and oblivion, which I would like to identify and describe in my article.
Twinned Renewable Energy Accumulation: Case of Wind and Hydro Energy
Authors: Brence Katarina , Kudurs Edgars , Valters Kārlis , Blumberga Dagnija 
Published: November 2023

Abstract
Renewable energy sources (RES) are the key element of sustainable energy systems. To accommodate the intermittency of wind (and solar) electricity generation, energy storage is critical. The aim of the study was to evaluate the potential of wind energy storage in the existing hydropower plant reservoirs in Latvia with the pumped hydroelectric energy storage (PHES) technology, considering the current and projected future wind energy capacities. An algorithm was developed and used for data aggregation and analysis, calculations, and forecasting. The three River Daugava hydroelectric power plants are the largest electricity producers in Latvia, and their generation capacity depends on seasonal variations. Currently, Latvia's electricity generation from RES is the highest during the spring season when maximum hydropower potential is utilized. However, wind energy has a potential to grow and could supplement hydropower throughout the year. Decreasing the existing administrative procedure heaviness to faster achieve the climate neutrality targets and energy autonomy by increasing RES development in Latvia is a way to create sustainable energy production. A rational future scenario in Latvia is to expand wind parks and integrate pumped hydroelectric energy storage systems in the existing cascade hydropower plants.
Numerical-Computational Model for Dynamic Nonlinear Analysis of Frames With Semi-Rigid Connection Considering the Damping Effect
Authors: De Souza Luiz Antonio Farani , Verdade Lucas Lauer 
Published: November 2023

Objective: the scope of this work is to present a numerical-computational model for transient dynamic nonlinear analysis of frames with geometric nonlinearity and semi-rigid connection.

Methodology: the equation of motion, which describes the structural dynamical system, is solved by the a-Generalized direct integration method associated with the standard Newton-Raphson method. The structures are discretized through the co-rotational formulation of the Finite Element Method considering the Euler-Bernoulli beam theory. The semi-rigid connection of structural members (beam-column and beam-support) is simulated by a connection element with zero length, which is described in terms of axial, translational and rotational stiffness.

Results and conclusion: From the numerical results of three structural systems (bi-fixed beam, L-shaped frame, and single-story frame) obtained with the free Scilab program, it is concluded that the definition of the type of connection is an important factor to be considered in the analysis of frames subjected to dynamic loads. Furthermore, structural damping, which is a measure of energy dissipation, drives the structure from a vibrating state to a resting state.

Research implications: Structural Engineering has been designing systems that cannot be analyzed and dimensioned without dynamic effects being considered. lack of knowledge of the levels and characteristics of the dynamic response can lead to system failure during the application of repetitive loading due to accumulation of structural damage. In this sense, the numerical model can represent a valuable engineering tool when it comes to the dynamic analysis of plane metallic structures with geometric nonlinearity.
PENGGUNAAN GAS AIR MATA DALAM PENGAMANAN PERTANDINGAN SEPAKBOLA DALAM PERSPEKTIF HUKUM POSITIF DI INDONESIA
Authors: Putra Dery Irawan Aditya , Zeinudin Moh. , Fithry Abshoril 
Published: November 2023

Result observationaling to point out 1. FIFA'S order and also PSSI was clear about sharp weapon purpose and Lachrymator may not be brought in evenless is utilized at deep stadium and also stadium outboard, that thing most decants deep section 19b. " No. fire arms or crowd control gases shall be carried or used (May not take in or utilizes firearm or lachrymator),", 2. forbidden FIFA order marks sense lachrymator, therefore law accountability did by football chairman or at so-called Indonesia with PSSI and Panita Is Executor or Panpel. But, since at oft lachrymator purpose Indonesia did by agency, therefore agency is mustinya even do law accountability as it were has already been brought together deep Section 13 Kapolri's regulations Number 1 Years 2009. FIFA'S conclusion and PSSI was clear forbidden deep water gas purpose because will trouble eye health stops the show.
L’équipement funéraire des dames de l’Égypte ancienne. Réflexions méthodologiques sur quelques exemples issus des nécropoles de Gourob
Authors: Venier Claudia 
Published: November 2023

En fonction des sources mobilisées, la documentation offre une vision contrastée de la femme dans l’Égypte ancienne. Après une remise en contexte, cette recherche se concentre sur ce que l’archéologie des assemblages funéraires peut apporter à notre connaissance de la société de cour du Nouvel Empire et en particulier de ses dames, à travers l’examen des nécropoles de Gourob. Le site de (Médinet el-)Gourob est associé, à partir du règne de Thoutmosis III (ca. 1479-1425 avant notre ère), à un domaine et une résidence des femmes de la famille royale et de la cour, souvent désignés par l’égyptologie contemporaine sous l’appellation de « palais-harem ». Les objets de Gourob, en particulier ceux mis au jour durant la campagne entreprise par la British School of Archaeology in Egypt en 1920 (G. Brunton et R. Engelbach), sont utilisés comme cas d’étude pour évaluer les possibilités de caractérisation sociologique des femmes inhumées dans les nécropoles qui entourent ce complexe palatial.