bluuebunny/crossref_metadata_2025_split huggingface dataset:
“At Sea, At Odds, Astray, Adrift”: Linguistic Destabilization in Jhumpa Lahiri’s Self-Translated Novel Whereabouts
Authors: Wanner Adrian 
Published: December 2023

Abstract
This article compares the Italian original of Jhumpa Lahiri’s novel Dove mi trovo (2018) with the English self-translation, which was published in 2021 under the title Whereabouts. Lahiri claims that her embrace of Italian was a means to escape the alienation caused by her bilingual upbringing in Bengali and English. Paradoxically, this quest for wholeness was coupled with insecurity in Italian, a language in which Lahiri only achieved fluency in middle age. Self-translation puts this linguistic ambiguity to a new stress test. In the confrontation between Lahiri’s Italian-language and Anglophone selves, her English becomes affected by Italian calques, creating a hybridized language mirroring the author’s own hybrid linguistic consciousness.
Interpreting Observed Interactions between Near-Inertial Waves and Mesoscale Eddies
Authors: Conn Scott , Fitzgerald Joseph , Callies Jörn 
Published: December 2023

Abstract
The evolution of wind-generated near-inertial waves (NIWs) is known to be influenced by the mesoscale eddy field, yet it remains a challenge to disentangle the effects of this interaction in observations. Here, the model of Young and Ben Jelloul (YBJ), which describes NIW evolution in the presence of slowly evolving mesoscale eddies, is compared to observations from a mooring array in the northeast Atlantic Ocean. The model captures the evolution of both the observed NIW amplitude and phase much more accurately than a slab mixed layer model. The YBJ model allows for the identification of specific physical processes that drive the observed evolution. It reveals that differences in the NIW amplitude across the mooring array are caused by the refractive concentration of NIWs into anticyclones. Advection and wave dispersion also make important contributions to the observed wave evolution. Stimulated generation, a process by which mesoscale kinetic energy acts as a source of NIW potential energy, is estimated to be 20 μW m−2 in the region of the mooring array, which is two orders of magnitude smaller than the global average input to mesoscale kinetic energy and likely not an important contribution to the mesoscale kinetic energy budget in this region. Overall, the results show that the YBJ model is a quantitatively useful tool to interpret observations of NIWs.
Preparation of berberine hydrochloride-Ag nanoparticle composite antibacterial dressing based on 3D printing technology
Authors: Chen Chen , Xie Maomei , Yan Yueling , Li Yongyuan , Li Zhiyao , Zhang Tong , Gao Zanyan , Deng Liyi , Wang Haixia 
Published: December 2023

In recent years, Ag nanoparticle (Ag NP)-loaded antibacterial dressings have attracted much attention in high-level medical dressings. However, the high cytotoxicity of Ag NP has always been a problem. In this paper, we examined the improvement of antibacterial activity of berberine hydrochloride (BBR) with Ag NP, the results showed that the combined use of BBR and Ag NP can effectively reduce the dosage of Ag NP while ensuring the inhibition of bacterial growth, thus an intermediate layer dressing containing combined drugs were prepared. At the same time, the top dressing of polyvinyl alcohol (PVA) solid film and the PVA bottom dressings with three kinds of leakage structures were prepared by 3D printing technology. Three kinds of PVA bottom dressings showed high quality consistency, and the greater the number of leak holes, the higher the porosity value of the dressing, while the swelling ratio value of the bottom layer dressing with three holes was the lowest. Finally, three types of BBR-Ag NP composite antibacterial dressings (3D-BBR-Ag NP) can be obtained by self-assembling of the top dressing, the intermediate layer dressing, and the bottom dressings with three kinds of leakage structures. The cumulative drug release results showed that dressing with more holes had a faster drug release rate compared to the other two ones with fewer leakage holes. Besides, five drug release kinetic models were used to investigate the cumulative BBR release profiles for three types of 3D-BBR-Ag NP. And the three types of composite dressings showed strong antibacterial activity after 6 h of cultivation with staphylococcus aureus. The study showed that the antibacterial activity of the self-assembled dressing prepared by combination of BBR with Ag NP can be improved, and the drug release rate of the hydrogel dressing can be flexibly controlled through 3D printing technology.
A meta-analysis of immunogenicity and safety of two versus single-doses of influenza A (H1N1) vaccine in person living with HIV
Authors: Zhang Teng , Geng Juan , Du Yazhe , Yang Haiyan , Jin Yuefei , Chen Shuaiyin , Duan Guangcai 
Published: December 2023

Purpose: Influenza vaccination of person living with HIV (PLWH) is a powerful means to tackle severe clinical outcomes. Few data on two doses of influenza vaccine in PLWH are available. Research Design: To evaluate the immunogenicity and safety of two doses of vaccine as compared with single dose in PLWH, we searched Pubmed, Embase, and web of science databases for relevant articles (January 2009 to April 2023). Pooled SMD or RR and 95% CI were calculated. Results: A total of 2436 participants from 14 studies were included. Compared to single dose influenza vaccine regimen, the pooled RR of seroprotection and seroconversion for two doses of vaccines was 1.14 (95%CI: 1.08–1.21) and 1.25 (95%CI: 1.16–1.34), respectively; the SMD of GMT was 0.42 (95%CI: 0.35, 0.49). Regarding safety, the fever risk in PLWH receiving two doses of vaccine was 3.42 fold higher than that of single dose vaccine, and the risk of myalgia had a quarter reduction. No serious vaccine-related adverse events were reported. Conclusions: Collectively, two doses of the vaccine are associated with a better immunogenicity and an acceptable safety in PLWH. Two doses of the adjuvant vaccination might be a superior vaccination regimen.nation regimen.
Systematic Framework for Esports Training: Informing eSports Training with the Learning Sciences
Authors: Chang Yoo Kyung , Chen Keying , Li Ziyue 
Published: December 2023

Intro With the rapid expansion of the esports industry, many esports training programs and academies have emerged. According to research, esports may lead to cognitive, metacognitive, academic and professional competencies if appropriately supported (Adachi & Willoughby, 2013). However, there is no systematic curriculum or guidance on how to identify and support these competencies through esports training. Methods This paper conducts a systematic review of literature from the learning sciences to provide a systematic rubric of competencies and instructional approaches to support them through esports training. The competencies that may be supported through esports are mapped along the game design principles as categorized along Mechanics, Dynamics, and Aesthetics (MDA) framework. Current training programs were analyzed to identify training approaches that can support these competencies across different contexts. Results There is a wide range of cognitive, self-regulation, social, academic, and career competencies that were found to be supported through video games. However, the development of such competencies depend on the availability of the learning opportunities and appropriate support provided to engage these opportunities, thus requiring a systematic framework for esports training. The training approaches that can be implemented to support diverse competencies from esports training, whether amateur or professional, are varied in modality, style, and structure. Conclusion The goal of this study is to inform the esports industry more largely, as well as the trainers, researchers, and designers with systematic and research-informed approaches to support future esports athletes, both professional and amateurs. Learning from the traditional field of athletic training, esports training should take more systematic approaches to design training curriculum and programs, as well as preparing the trainers.
Continuous Electrocardiographic Monitoring for 24 Hours Before Death in Patients with Terminal Cancer
Authors: Sato Ko , Baba Mika , Morita Tatsuya , Masukawa Kento , Shima Yasuo , Tsuneto Satoru , Kizawa Yoshiyuki , Miyashita Mitsunori 
Published: December 2023

Background Purposeless physiological monitoring at the end-of-life is not recommended. However, studies on how families feel regarding the death of patients with terminal cancer without continuous electrocardiographic monitoring (CEM) are lacking. Objectives To explore the impact on the quality of care and the feelings and psychological distress experienced by families when CEM is not used during the 24 hours preceding a patient’s death. Methods In this multicenter cross-sectional, self-report questionnaires were distributed to 1087 bereaved families at Japanese specialized palliative care units in 2018. Results Out of 671 responses, 394 valid responses were analyzed. Families of nonmonitored patients (NM-group) accounted for 79.2%, while those with bedside electrocardiogram monitoring (MB-group) and remote nurse station monitoring (MC-group) comprised 11.9% and 8.9%, respectively. In the NM-group, 85.5% expressed satisfaction without CEM, which was more than 10% lower than other groups. While 14% in the NM-group desired patient monitoring, families who received adequate explanations about CEM had lower proportions compared to the MB-group ( P = .021). Univariate analyses showed no significant differences in evaluations of the quality of care and families’ psychological distress (mean scores of Overall Care Satisfaction, Care Evaluation Scale, Good Death Inventory, Brief Grief Questionnaires) across all groups. Conclusion While the majority of NM-group were satisfied with their patient’s care without CEM, the proportion of dissatisfied families was higher than in other groups. Although not using CEM is not a major hindrance to end-of-life care for patients with terminal cancer, providing sufficient explanations may be important for satisfactory care.
Evaluation of the effects of mono or combined use of topical antiglaucomatous drops on conjunctival flora and antibiotic susceptibility
Authors: Ekici Gok Zarife , Gunduz Ayten , Bozgül Penpe Gül 
Published: December 2023

Purpose To evaluate the effects of mono or combined use of topical antiglaucomatous drops (AGD) on conjunctival flora and antibiotic susceptibility. Methods The study group consisting of 84 glaucoma patients using AGDs and 32 healthy controls were evaluated. Groups were formed according to the use of 1, 2 and 3 AGDs. A swab was taken from the conjunctival sac from each patient and cultures were made. Patients with conjunctival hyperemia were classified according to their appearance. Results The mean age was 58.61 ± 14.55 years. Conjunctival culture positivity was 84.37%, 89.28% and 90.6% according to the use of 1, 2, and 3 AGDs, respectively, and it was 93.75% in the control group. Staphylococcus hominis (S. hominis) was statistically significantly higher in all glaucoma patients compared to healthy volunteers ( p = .030). S. hominis was significantly higher especially in those using 2 (42.85%) and 3 (50%) AGDs, compared to those who received mono treatment (31.25%). Candida spp. was also significantly higher in glaucoma patients ( p = .039). In patients with conjunctival hyperemia in glaucoma patients, the most common two bacteria were S. hominis (55.5%) and Staphylococcus epidermidis (S. epidermidis) (33%), respectively. In the relationship between isolated bacterial species and conjunctival hyperemia grades, Bacillus spp. ( p = .013) was statistically significant. In glaucoma patients, norfloxacin and erythromycin resistance were found to be statistically significantly higher compared to the control group ( p = .01). Conclusion Considering the statistically significant increase in isolates in all glaucoma patients, we suggest that more care should be taken in terms of infection in surgical procedures planned for glaucoma patients
What is the most appropriate comparator group to use in assessing the performance of primary total hip prostheses within the community?
Authors: Ghadirinejad Khashayar , Graves Stephen , de Steiger Richard , Pratt Nicole , Solomon Lucian B , Taylor Mark , Hashemi Reza 
Published: December 2023

Background: There are variations in the performance of individual prostheses used in hip replacements. Some of which have unexpectedly higher revision rates – outliers. The Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) has established a standardised multi-stage approach for identifying these devices. This is done by comparing the revision rates of individual prostheses to all other prostheses in class, with the exception of large head metal-on-metal (LHMoM) prostheses. However, improvements in device design and performance over time have required a need to reconsider the comparator group. This study aimed to identify a more specific comparator to better reflect contemporary surgical practice. Methods: The time to first revision was estimated on the data of 413,417 primary total conventional hip replacements undertaken for osteoarthritis (OA) from 01 January 2003 to 31 December 2019. Survivorship analyses with stepwise exclusions were undertaken. The first exclusion was LHMoM, followed by other non-modern bearing surfaces (defined as all the bearing couples except metal or ceramic heads on cross-linked polyethylene and mixed ceramic-on-ceramic), and then devices with modular neck-stem design or used for specific purposes (incl. constrained, dual-mobility, and head size <28 mm). Lastly, all remaining prostheses previously identified as having a higher than anticipated rate of revision (HTARR) were also excluded. Results: These exclusions progressively reduced the cumulative percent revision (CPR) rate. The final comparator, which only includes satisfactory-performed prostheses of contemporary design and use, has a 10-year CPR of 4.30% (95% CI, 4.2–4.41) which is lower than 4.93% (95% CI, 4.84–5.02) for the current comparator used by the AOANJRR (all prostheses excluding LHMOM). Over the study period, 13 additional components were identified utilising the modified comparator. Conclusions: The calculation of the comparator revision rate should be re-evaluated to include only modern prosthesis constructs to ensure that poorly performing prostheses are identified early.
Validation, performance, and reliability of two automated tests for vitamin B12 and folate assay
Authors: Bianciardi Simone , Tesi Giulia , Cerutti Helena , Cartocci Alessandra , Guerranti Roberto , Silvestrini Caterina , Gori Sabrina , Bandini Tommaso , Brogi Alessandra , Leoncini Roberto 
Published: December 2023

Background: Deficiency of Vitamin B12 and folate may determine hematological, neurological, and metabolic alterations; therefore, an accurate quantification of their serum levels is required, especially in the presence of symptoms that might suggest a deficiency. CHORUS VIT B12 and CHORUS FOLATE are two automated immunoassays, developed to quantify vitamin B12 and folate, respectively, in human serum. Design and methods: This single-center, non-pharmacological, diagnostic study described the validation and characterization of CHORUS VIT B12 and CHORUS FOLATE, with a specific focus on performance, precision, and reliability. For each assay, 500 serum samples were analyzed. A comparison between CHORUS assays and commercially available kit was also performed. Results: For CHORUS VIT B12 the lower limit of quantification (LLoQ) was 165.0 pg/mL and the upper LoQ (ULoQ) was 1846.8 pg/mL. The assay was linear within the calibration range (150–2000 pg/mL) and the accuracy was described with the International Standard Vitamin B12, Serum Folate, HOLO TC (NIBSC code: 03/178), with a mean recovery on two lots of 111%. For CHORUS FOLATE (calibration range of 2.0–20.0 ng/mL), LLoQ was 2.0 ng/mL and ULoQ 19.6 ng/mL. The linearity was demonstrated from 2.4 to 20.0 ng/mL; the accuracy was described with the International Standard mentioned above, achieving a mean recovery on three lots of 92%. The lowest and highest values of both CHORUS and COBAS kits were similar and the median values did not significantly vary. Conclusion: CHORUS VIT B12 and CHORUS FOLATE performed well, accurately, and reliably in quantifying vitamin B12 and folate in human serum.
Dating Apps and Mental Health Status: Is There a Link?
Authors: Freire Daniela , Rema João , Novais Filipa 
Published: December 2023

Background: The development of SexTech (Sexuality + Technology) has profoundly altered the way relationships are experienced, and an accessible example of that, which has millions of users, is the dating apps (Tinder, Grindr, and Bumble), which can locate partners with common interests nearby. Aim: To determine whether the use of dating apps is associated with higher levels of stress, anxiety, or depression and to assess the main motivations for using dating apps in young people. Methods: An online questionnaire addressed to university students was designed with an initial part aimed at collecting the sociodemographic data of the sample, a second part to address motivations for the use of dating applications, and a third part designed to evaluate the anxiety and depression scores of the participants. Outcomes: This study had two main outcomes: anxiety and depression scores measured using the Depression, Anxiety, and Stress Scale (DASS-21). Results: Four hundred and ninety-seven people participated in the study, with an average age of 21.8 years. Seventy percent were female. Thirty-four percent of the students use or have used these applications. Recent users showed a statistically significantly higher depression score than non-users. However, the ones who ever used dating apps did not report significantly higher scores than non-users. Homosexual participants have a statistically significantly higher anxiety and depression score than heterosexual. The most stated reason for using apps was “meeting new people,” followed by “entertainment” and “curiosity.” Clinical Implications: To promote mental health and sex education, have more tools to respond to topics related to sexuality and technology. Strengths and Limitations: The DASS-21 questionnaire is an adequate tool for screening for anxiety and depression disorders. However, other methods should be added to establish a formal diagnosis. The methodology applied in this research allowed us to establish an association between variables but not causality. In any case, we argue that our results shed light on the impact that the much-used dating apps have on mental health and the main reasons for their use. Conclusion: Being a user of dating apps does not seem to impact mental health; however, recent use and belonging to a minority constitute predictors of more anxiety and depression symptoms.
Rice Basic Helix-Loop-Helix 079 (OsbHLH079) Delays Leaf Senescence by Attenuating ABA Signaling
Authors: Kim Suk-Hwan , Yoon Jungwon , Kim Hanna , Lee Sang-Ji , Paek Nam-Chon 
Published: December 2023

AbstractLeaf senescence represents the final phase of leaf development and is characterized by a highly organized degenerative process involving the active translocation of nutrients from senescing leaves to growing tissues or storage organs. To date, a large number of senescence-associated transcription factors (sen-TFs) have been identified that regulate the initiation and progression of leaf senescence. Many of these TFs, including NAC (NAM/ATAF1/2/CUC2), WRKY, and MYB TFs, have been implicated in modulating the expression of downstream senescence-associated genes (SAGs) and chlorophyll degradation genes (CDGs) under the control of phytohormones. However, the involvement of basic helix-loop-helix (bHLH) TFs in leaf senescence has been less investigated. Here, we show that OsbHLH079 delays both natural senescence and dark-induced senescence: Overexpression of OsbHLH079 led to a stay-green phenotype, whereas osbhlh079 knockout mutation displayed accelerated leaf senescence. Similar to other sen-TFs, OsbHLH079 showed a gradual escalation in expression as leaves underwent senescence. During this process, the mRNA levels of SAGs and CDGs remained relatively low in OsbHLH079 overexpressors, but increased sharply in osbhlh079 mutants, suggesting that OsbHLH079 negatively regulates the transcription of SAGs and CDGs under senescence conditions. Additionally, we found that OsbHLH079 delays ABA-induced senescence. Subsequent RT-qPCR and dual-luciferase reporter assays revealed that OsbHLH079 downregulates the expression of ABA signaling genes, such as OsABF2, OsABF4, OsABI5, and OsNAP. Taken together, these results demonstrate that OsbHLH079 functions in delaying leaf yellowing by attenuating the ABA responses.
Comparison of the pulling technique versus the standard technique in microsurgical subinguinal varicocelectomy: a randomized controlled trial
Authors: Kotb Sameh , Abdel-Rassoul Mohammed A. , Elkousy Mohamed Magdy , El-Shorbagy Galal , Elsayed Ahmed S. , Abdel-Rahman Sherif , Sayed Amr Moustafa 
Published: December 2023

Abstract
Background
We compare the outcome of microsurgical subinguinal varicocelectomy (MSV) using the pulling technique (P-MSV) compared to the standard technique (S-MSV).

Methods
A total of 60 patients were diagnosed with varicocele compounded with infertility and/or scrotal pain not responding to medical treatment. Twenty-nine patients were randomized to the P-MSV, while 31 were randomized to S-MSV. The number of ligated veins was counted intraoperative and compared. Follow-up was done at 1 and 3 months including clinical examination, scrotal duplex ultrasound scan, and semen analysis.

Results
A total of 85 sides were operated upon, 43 (50.5%) were done by the P-MSV technique while 42 (49.5%) were done by the S-MSV technique. The median gained cord length after using the P-MSV was [3 cm; IQR 2–5 cm]. For the P-MSV technique, the mean number of detected internal spermatic veins after cord pulling was (4 ± 1.3 SD) compared to (6 ± 1.4 SD) before pulling (P value < 0.01) and for the S-MSV was 3 (2.75–5). There was no statistical or clinically significant difference in the perioperative outcomes between both groups. The overall conception rate was 47.1%. Ninety-two percent of patients complaining of preoperative scrotal pain had resolution of the pain on follow-up with no statistical difference between both techniques (P values 0.53, 0.3 respectively). There was no statistical difference in the recurrence rate between both groups (P = 0.11). The number of ligated veins decreased significantly using the P-MSV technique leading to an improvement in the surgical feasibility of MSV.

Conclusion
There is a significant benefit for the new pulling technique in decreasing the number of internal spermatic veins which leads to improving the surgical feasibility of microsurgical varicocelectomy.