bluuebunny/crossref_metadata_2025_split huggingface dataset:
La campaña admirable, una independencia consolidada
Authors: Tigasi Vega Nayeli Elizabeth , Quinatoa Coque Mayra Beatriz 
Published: February 2025

En esta investigación bibliográfica se realiza el análisis de acontecimientos históricos en los que se documentaron el largo y arduo proceso de independencia venezolana, a la vez se realizó un análisis de los eventos que están dentro de la campaña admirable y de los personajes que juegan un papel importante en esta constante lucha. La investigación de fuentes confiables permite comprender a profundidad como sucedieron y como se desarrollar estos enfrentamientos con el poder español. La lucha por tener una Venezuela libre fue muy dura y compleja, empezando con una primera independencia fallida en 1812, sin embargo, bajo el liderazgo de Simón Bolívar y sus grandes ideologías por liberar a Venezuela del poder español se desato una seria de batallas y decretos en contra del poder realista, la cual para la historia fue denominada como campaña Admirable, todas las batallas fueron victoriosas para el ejercito libertador, sin embargo, aún no lograba su liberación total. Sin embargo, las batallas que definieron una independencia consolidada de Venezuela fueron las “Batalas de Boyacá” y la “Batal a de Carabobo”, actos que a pesar de ser largas y sangrientas, pues duro 5 horas y dejando un total de mil muertos por parte de las tropas enemigas, sin embargo, se logró la victoria, derrocando al mandato español, además de las grandes estrategias y aliados que acompañaron a Bolívar en esta larga pero fructífera lucha por liberar a Venezuela del realismo español.
Propuesta de requisitos para la aplicación de la economía circular en la restauración turística del destino La Habana
Authors: Romaní Bendig Beatriz , Ginarte López Sandra , Espinosa Manfugás Julia Ma , Pérez Cabelleira Luisa , Route María del Pilar 
Published: February 2025

La presente investigación tuvo como objetivo proponer requisitos para la aplicación de la economía circular en la restauración turística del destino La Habana. Para el cumplimiento de este objetivo, fueron empleados métodos de investigación teóricos, empíricos y estadísticos. Se realizó una entrevista semiestructurada a los especialistas de calidad y operaciones de alimentos y bebidas del Ministerio de Turismo, y además, se aplicó un cuestionario a los especialistas de calidad y operaciones de alimentos y bebidas de las OSDES Hoteleras, Empresa Extrahotelera Palmares, Ministerio de Comercio Interior (Mincin), así como a los presidentes de la Asociación Culinaria de Cuba, la Asociación de Cantineros de Cuba y la Asociación de Sommeliers de Cuba. Se llevó a cabo una revisión de literatura especializada y normativas establecidas sobre esta temática. El procesamiento de los datos implicó el cálculo de frecuencias absolutas y relativas, el cálculo del índice del Alfa de Cronbach, así como la realización del Diagrama de Pareto. La validación de la propuesta se realizó por un grupo de expertos, a través del método de ANOCHI. Los resultados de la investigación permitieron constatar que los retos vitales para la aplicación de la Economía Circular en restaurantes turísticos del destino La Habana son: la baja capacitación del personal, la falta de recursos en el destino y la carencia de infraestructura necesaria. Se elaboró y validó la propuesta requisitos, la cual fue estructurada en requisitos generales y específicos, los que incluyen un total de 14 apartados.
El impacto de las redes sociales en los adolescentes
Authors: Guerra Poalasin Diego Omar , Ruales Flores Francisco Israel 
Published: February 2025

Introducción: Las redes sociales han transformado la forma en que los adolescentes interactúan, se comunican y acceden a la información. Sin embargo, su uso también ha suscitado preocupaciones respecto a su impacto en aspectos como la salud mental, el rendimiento académico y la sociabilidad. Este estudio analiza los efectos positivos y negativos de estas plataformas en la vida de los adolescentes, destacando su influencia en áreas clave de desarrollo. Objetivo: El principal objetivo de este estudio es identificar los efectos del uso de redes sociales en los adolescentes, evaluando su influencia en la salud mental, el desempeño académico y las interacciones sociales. Asimismo, busca proponer estrategias para fomentar un uso saludable y equilibrado de estas plataformas. Metodología: Esta investigación tiene un enfoque mixto cualitativo y cuantitativo. Resultados: Los resultados revelaron que el 70% de los adolescentes utiliza redes sociales más de tres horas al día, lo que influye directamente en su rendimiento académico y en sus patrones de sueño. El 60% de los adolescentes reportó sentir presión por alcanzar estándares de validación social. Sin embargo, también se identificaron beneficios, como el acceso a recursos educativos y el fortalecimiento de comunidades de apoyo emocional. Conclusiones: El impacto de las redes sociales en los adolescentes es ambivalente, con efectos tanto positivos como negativos. Si bien estas plataformas pueden ser útiles para el aprendizaje y la conexión social, el uso excesivo puede llevar a problemas como ansiedad, adicción y disminución del rendimiento académico. Es fundamental promover una educación digital y estrategias de autorregulación para mitigar los riesgos y maximizar los beneficios en esta etapa crucial del desarrollo. Área de estudio general: Tecnología. Área de estudio específica: Desarrollo de software. Tipo de estudio: Artículo revisión bibliográfica
El uso de Simuladores Digitales para la Enseñanza de Ciencias Sociales
Authors: Ortiz-Velásquez Norelis , Valencia-Cabrera Yalitza , Campoverde-Martínez Gabriela , Flores-Cumbicus Rocío , Núñez-Naranjo Aracelly 
Published: February 2025

Introducción: El avance de la tecnología ha impactado de manera significativa en varios ámbitos de la vida cotidiana, especialmente en el sector educativo, por lo tanto, el presente artículo abordará aspectos relevantes para comprender la importancia de los simuladores digitales en la educación. Objetivo: analizar el impacto de los simuladores digitales en la educación mediante un análisis teórico. Metodología: la técnica de investigación utilizada fue la revisión bibliográfica, el procedimiento se basó en un análisis exhaustivo de estudios previos de otros autores. Resultados: el uso de simuladores digitales en el contexto educativo permite lograr una educación de calidad enfocada en las necesidades individuales de los estudiantes, garantizando una formación integral exitosa en el ámbito personal, académico y profesional; el uso de plataformas digitales debe regirse estrictamente a normativas pertinentes que garanticen la seguridad de los datos personales de los estudiantes. Conclusión: la implementación de herramientas digitales en el contexto educativo brinda a los docentes oportunidades de potenciar el proceso de aprendizaje-enseñanza, permitiendo a los estudiantes poner en práctica los conocimientos aprendidos, fortaleciendo competencias valiosas para que en un futuro sean capaces de enfrentar desafíos del mundo laboral de manera adecuada.
Peran Kepuasan Kerja Sebagai Variabel Mediasi Pada Pengaruh Gaya Kepemimpinan dan Lingkungan Kerja Terhadap Kinerja Karyawan Pada TCT Teknik
Authors: Putri Retrin Irene , Zain Efendy , Marhamah Siti 
Published: February 2025

Penelitian ini bertujuan untuk mengetahui peran kepuasan kerja sebagai variabel mediasi pada pengaruh gaya kepemimpinan dan lingkungan kerja terhadap kinerja karyawan. Penelitian ini menggunakan metode Partial Least Square Structural Equation Modeling dengan aplikasi WarpPLS 7.0 dan menggunakan sampel jenuh dari populasi sebanyak 64 orang karyawan dari TCT Teknik Jakarta. Data dikumpulkan dengan pengisian kuesioner. Temuan menunjukkan bahwa: Gaya Kepemimpinan , Lingkungan Kerja, dan Kepuasan Kerja berpengaruh positif dan signifikan terhadap Kinerja Karyawan, menyiratkan bahwa dengan adanya kesesuaian pada penerapan gaya kepemimpinan, lingkungan kerja yang memadai, dan rasa kepuasan kerja yang tinggi, akan berdampak pada peningkatan kinerja karyawan. Gaya Kepemimpinan dan Lingkungan Kerja berpengaruh positif dan signifikan terhadap Kepuasan Kerja, menyiratkan bahwa rasa puas akan meningkat jika pemimpin memperlakukan karyawan sesuai dengan yang diharapkan dan lingkungan kerja yang ada tidak menghalangi karyawan untuk beraktivitas. Kepuasan Kerja memediasi pengaruh Gaya Kepemimpinan terhadap Kinerja Karyawan namun Kepuasan Kerja tidak memediasi pengaruh Lingkungan Kerja terhadap Kinerja Karyawan.
Oral Health of Astronauts in Short- and Long-Term Missions in Space
Authors: Del Fabbro Massimo , Khijmatgar Shahnawaz , Vandenberghe Bart , Kijak Edward , Kulesa-Mrowiecka Malgorzata , Singhal Ishita , Lorusso Felice , Xavier Basil B. , Sampson Victoria , Marfia Giovanni , Neefs Dirk , Tartaglia Gianluca M. 
Published: February 2025

INTRODUCTION: Space exploration presents unique challenges to human health due to space radiation, reduced gravity, and prolonged isolation. Astronauts should be prepared to manage medical and dental emergencies. This scoping review maps the evidence on oral health alterations and dental emergencies faced by astronauts during short- and long-term space missions.
METHODS: A “Topical Team” assembled by the European Space Agency performed the review described herein. An electronic search was conducted on scientific databases, reference lists of relevant papers, specific textbooks, and space agencies’ databases. Inclusion criteria encompassed studies related to dental medicine in microgravity or outer orbital space conditions. Results are presented through narrative format.
RESULTS: Out of 23,686 studies identified, 467 were considered eligible and 80 (54 reviews and 26 human-based studies) were included. The latter were classified into three broad topics: microbiology, space physiology and medicine, and space dentistry. Among the studies involving human subjects, 17 involved individuals who had spent time in space. There are only a few studies about oral health modifications and issues during spaceflight and those have limited evidence. Dental emergencies in space are relatively rare events that tend to increase with mission duration.
DISCUSSION: The impact of microgravity on oral health requires further investigation. Preflight and in-flight measures should focus on prevention and treatment protocols for various dental issues to ensure crew safety and mission success. Understanding and addressing factors affecting oral health in microgravity will enhance the well-being of astronauts and the success of human exploration missions in space.
Del Fabbro M, Khijmatgar S, Vandenberghe B, Kijak E, Kulesa-Mrowiecka M, Singhal I, Lorusso F, Xavier BB, Sampson V, Marfia G, Neefs D, Tartaglia GM. Oral health of astronauts in short- and long-term missions in space. Aerosp Med Hum Perform. 2025; 96(2):168–179.
The association of lipid accumulation product with inflammatory parameters and mortality: evidence from a large population-based study
Authors: Chi Yi , Zhang Yiqing , Lin Huang , Zhou Shanshan , Jia Genlin , Wen Wei 
Published: February 2025

BackgroundObesity is closely associated with lipid metabolism, and the accumulation of lipids leads to low-level inflammation in the body, which can trigger cardiovascular disease. This study aimed to explore the association between a novel marker of lipid accumulation, the abdominal volume index (AVI), inflammatory parameters, and mortality.MethodsThis study enrolled 2,109 older adult senior citizens (aged over 60 years) with hypertension from the National Health and Nutrition Examination Survey. The primary endpoints included all-cause mortality and cardiovascular mortality, which were assessed by linking the data to the National Death Index records. Cox regression model and subgroup analysis were constructed to investigate the associations between AVI and both all-cause and cardiovascular mortality. Restricted cubic splines were employed to further explore the relationships among AVI, inflammatory parameters, and mortality. By considering inflammatory factors as mediators, we investigate the mediating effects of AVI on mortality.ResultsAfter a median follow-up of 69 months, there were 1,260 deaths, with 337 attributed to cardiovascular causes within the older adult population studied. In the multivariable-adjusted model, AVI was positively associated with both all-cause and cardiovascular mortality [Hazard Ratio (HR) = 1.09, 95% CI = 1.06–1.11 for all-cause mortality; HR = 1.07, 95% CI = 1.03–1.12 for cardiovascular mortality]. Kaplan-Meier survival plots indicated an overall median survival time of 144 months. Mediation analysis revealed that Systemic Inflammatory Response Index (SIRI), Monocyte-to-HDL ratio (MHR), and Neutrophil-to-Lymphocyte ratio (NLR) mediated 27.15%, 35.15%, and 16.55%, respectively, of the association between AVI and all-cause mortality.ConclusionAVI is positively associated with all-cause mortality in older adults with hypertension, and this association appears to be partially mediated by inflammatory parameters.
Prevalence of viral hepatitis B and C infection and associated factors among pregnant women in southeast Ethiopia: community-based crossectional study
Authors: Mohammed Nuruzelam , Kassim Jeylan , Aliyi Ahmednur Adem , Abdurebi Muhammed Jemal 
Published: February 2025

IntroductionHepatitis B or C infection during pregnancy increases the risk of vertical transmission, which is risky for the growing fetus and the newborn. In order to prevent such adverse effects and outcomes, it is crucial to understand the scope of the problem. However, absence of data on community-based Prevalence of viral hepatitis among pregnant women and conflicting evidence from facility-based study shows there is paucity of information on seroprevalence of Hepatitis B and C virus infection among pregnant women.MethodsA community-based cross-sectional study was conducted on 422 pregnant women selected from three selected kebeles of Robe town. Study participants were selected using systematic sampling technique. Data were collected through pretested interviewer administered questionnaire and three milliliter blood sample were collected and tested for HBsAgn and Anti-HCV Antibodies. Descriptive statistics such as frequency, mean, and standard deviation were used to summarize data. Binary logistic regression was used to identify factors associated with occurrence of Hepatitis B and C virus among pregnant women. Accordingly, variables with P value &lt; 0.25 in bivariate logistic regression were declared as candidate for multivariable logistic regression. From multivariable logistic regression adjusted odds ratio with 95% confidence interval were computed. Those variable with p- value &lt;0.05 were declared as factor associated with dependent variable.Results and discussionA total of 410 pregnant women participated in the study, which yielded a response rate of 97.2%. The seroprevalence of hepatitis B and C virus infections was found to be 7.6%, and 2.2% respectively, whereas one (0.24%) woman was co-infected. History of dental extraction (AOR = 2.70, 95% CI 1.09, 6.69), hospital admission (AOR = 6.96, 95%CI 1.73, 27.99), household contact (AOR = 3.93, 95% CI 1.37, 11.25), tattooing (AOR = 3.50 95% CI 2.31, 12.35), sexually transmitted infection (AOR = 11.42 95% CI 3.10, 42.35) were significantly associated with HBsAg infection whereas history of blood transfusion (AOR 5.58, 95% CI 1.03, 30.05, P = 0.045) and household contact (AOR 7.49, 95% CI 1.34, 41.76) were significantly associated with HCV infection among pregnant women.ConclusionsThe Seroprevalence of HBV and HCV was moderate endemicity according to WHO classification. Finding from present study shows different factors that plays great role in transmission of viral hepatitis.
Case report: Successful laparoscopic management of early abdominal pregnancy
Authors: Li Haixia , Feng Limin , Zhang Shengpeng 
Published: February 2025

BackgroundAbdominal pregnancy is characterized by the implantation of the gestational sac within the peritoneal cavity, specifically outside the fallopian tubes, ovaries, and cervix. This exceedingly rare form of ectopic pregnancy accounts for about 1% of all ectopic pregnancies. When rupture occurs, it can result in a life-threatening situation for the patient, necessitating immediate medical intervention.Case informationIn this study, we report a 33-year-old female patient who presented with abdominal pain and was subsequently diagnosed with an early abdominal pregnancy. Laparoscopic intervention revealed gestational tissue and a rupture site located in the pouch of Douglas. The gestational tissue was successfully excised via laparoscopy, and the rupture site was sutured to achieve hemostasis. Postoperative histopathological analysis confirmed the presence of chorionic villi and trophoblast cells.ConclusionThis case highlights the critical importance of precise diagnosis and laparoscopic intervention in the management of abdominal pregnancy. It is imperative for clinicians to exercise a prudent approach in the diagnosis and treatment of abdominal pregnancy, utilizing a comprehensive assessment that integrates medical history, clinical manifestations, and auxiliary diagnostic tests to enhance the detection and comprehension of this condition.
Association between serum carotenoids levels and endometriosis risk: evidence from the National Health and Nutrition Examination Survey
Authors: Huang Jian 
Published: February 2025

BackgroundThe relationship between serum levels of carotenoids and endometriosis remains largely unknown. The aim of this study is to assess the association between serum levels of major carotenoids (α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin, and trans-lycopene) and the risk of endometriosis in US women.MethodsThe data were obtained from the 2001–2006 National Health and Nutrition Examination Surveys (NHANES), which included a total of 3,636 women aged 20 to 54. Serum levels of α-carotene, β-carotene, β-cryptoxanthin, lutein/zeaxanthin, and trans-lycopene were measured using high performance liquid chromatography (HPLC) with photodiode array detection. Endometriosis was defined as self-report. Weighted multivariate logistic regression analyses were conducted to evaluate the associations of the serum levels of the major carotenoids with endometriosis risk. Additionally, restricted cubic spline (RCS) was employed to assess the possibility of nonlinear associations. Finally, subgroup analyses were utilized to estimate the influence of several covariates on the associations.ResultsWeighted multivariate logistic regression analyses showed that, after adjusting for all covariates taken into account, there was a significant association between serum lutein/zeaxanthin levels and reduced risk of endometriosis (Quartile 3 vs. Quartile 1: odds ratio [OR] = 0.62, 95% confidence interval [CI]: 0.42–0.90; Quartile 4 vs. Quartile 1: OR = 0.54, 95% CI: 0.36–0.81, P for trend = 0.001). However, no significant associations of serum levels of other carotenoids with endometriosis were found in multivariable-adjusted models that included all covariates. RCS analysis did not reveal any non-linear relationships. Subgroup analyses indicated that the inverse association between serum lutein/zeaxanthin levels and reduced endometriosis risk was significant only in individuals under 40 years of age, in both White and non-White populations, in smokers, and among those who had ever used oral contraceptives.ConclusionSerum lutein/zeaxanthin levels may offer protective effects against endometriosis in specific subpopulations. Further prospective research is necessary to validate these findings.
Leiomyosarcomas of the inferior vena cava: diagnostic features on contrast-enhanced CT, ultrasonography and MRI
Authors: Xu Xiaolin , Zhao Shilei , Xue Lifang 
Published: February 2025

PurposeTo evaluate clinical presentation and imaging characteristics of leiomyosarcomas of the inferior vena cava (IVC LMS) using contrast-enhanced CT (CECT), ultrasonography (US), magnetic resonance imaging (MRI), and to identify features that facilitate early and accurate pre-operative diagnosis.Materials and methodsOur study enrolled 21 patients with pathologically confirmed IVC LMS from October 2015 to June 2022. All participants underwent CECT, and additionally, 12 participants had US examinations and 3 had MRI. Images were independently reviewed by two experienced radiologists. The clinical presentations and diagnostic characteristics were recorded.ResultsThe study involved 16 female and 5 male patients, with an average age of 55 ± 11 years (ranging from 34 to 80 years). Common clinical symptoms included abdominal pain, back pain, leg discomfort, abdominal distension, jaundice, and the presence of an abdominal mass. On CT scans, a large, lobulated, heterogeneous mass with progressive enhancement was typically seen in 13 of the 21 patients (61.9%). Ultrasonography revealed that IVC LMS typically presented as a lobulated, heterogeneous, hypoechoic mass. Color Doppler imaging evaluated lumen obstruction in 8 of the 12 patients (66.7%), and high velocity flow signals were detected by Pulsed wave Doppler in 4 of the 12 patients (33.3%). On MRI, IVC LMS presented as a heterogeneous mass that exhibited intermediate intensity on T1-weighted images, slightly high intensity on T2-weighted images and high intensity on diffusion-weighted images.ConclusionSeveral diagnostic characteristics on CECT, US and MRI could aid in the diagnosis of IVC LMS. The detection of a heterogeneous mass with progressive enhancement along the inferior vena cava on CECT was strongly indicative of IVC LMS. Both CT and US are effective in accurately indicating the location of the tumor within the IVC.
Exploring the role of artificial intelligence in chemotherapy development, cancer diagnosis, and treatment: present achievements and future outlook
Authors: Abdul Rasool Hassan Bassam , Mohammed Ali Haider , Hallit Souheil , Malaeb Diana , Hosseini Hassan 
Published: February 2025

BackgroundArtificial intelligence (AI) has emerged as a transformative tool in oncology, offering promising applications in chemotherapy development, cancer diagnosis, and predicting chemotherapy response. Despite its potential, debates persist regarding the predictive accuracy of AI technologies, particularly machine learning (ML) and deep learning (DL).ObjectiveThis review aims to explore the role of AI in forecasting outcomes related to chemotherapy development, cancer diagnosis, and treatment response, synthesizing current advancements and identifying critical gaps in the field.MethodsA comprehensive literature search was conducted across PubMed, Embase, Web of Science, and Cochrane databases up to 2023. Keywords included “Artificial Intelligence (AI),” “Machine Learning (ML),” and “Deep Learning (DL)” combined with “chemotherapy development,” “cancer diagnosis,” and “cancer treatment.” Articles published within the last four years and written in English were included. The Prediction Model Risk of Bias Assessment tool was utilized to assess the risk of bias in the selected studies.ConclusionThis review underscores the substantial impact of AI, including ML and DL, on cancer diagnosis, chemotherapy innovation, and treatment response for both solid and hematological tumors. Evidence from recent studies highlights AI’s potential to reduce cancer-related mortality by optimizing diagnostic accuracy, personalizing treatment plans, and improving therapeutic outcomes. Future research should focus on addressing challenges in clinical implementation, ethical considerations, and scalability to enhance AI’s integration into oncology care.