bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19 early assessment outcomes on Internet data: A review study
Authors: Yu Suz-I , Hu Ching-Wen , Hsu Ya-Hui , Tseng Yao-Hsien , Fan Hueng-Chuen 
Published: October 2023

Abstract

Background:
Severe acute respiratory syndrome coronavirus (SARS-CoV)-2, which is a novel coronavirus from the same family as SARS-CoV and Middle East respiratory syndrome coronavirus, has overrun worldwide leading the World Health Organization to declare a pandemic.

Objectives:
This study aimed to clarify high-risk factors for coronavirus disease 2019 (COVID-19) with multivariate analysis and establish a predictive model of disease progression to help clinicians better choose a therapeutic strategy. Clinical implications of COVID-19 will push society past this pandemic with the latest in technology and research and further studies into the pathogenesis evaluation.

Methods:
A comprehensive search of the PubMed, MEDLINE, Uptodate, Natural MEDLINE, Embase, and Web of Science electronic databases was made, using the following search terms: “COVID-19,” “COVID-19 SCORE,” “COVID-19 diagnosis,” “COVID-19 management,” “coronavirus,” and “SARS-CoV-2.” We included scientific publications from December 1, 2019, to April 31, 2021, which focused on clinical characteristics and treatments for SARS-CoV-2 that were eligible for inclusion. We screened all reference lists of relevant studies to identify any missing publications.

Results:
A total of 40 articles were reviewed. We revealed that the present review emphasizes that the higher risk of comorbidity, age, lymphocyte, and lactate dehydrogenase (CALL) score has a good predictive value for mortality in COVID-19 than the CURB-65 score. The 2021–2022 SARS-CoV-2 Omicron variant is a global concern due to its rapid spread to displace the main Delta and Omicron variants. This scoring system has been designed to categorize based on the systemic disease involvement and, thus, would serve as a reliable indicator for prognostic assessment in patients.

Conclusion:
This review highlights the higher predictive value of the CALL score for higher risk COVID-19 mortality than the CURB-65 score. The 2021–2022 SARS-CoV-2 Omicron variant is of global concern as its rapid spread has replaced the main Delta and Alpha variants. Scoring systems are designed to categorize disease and, thus, serve as reliable indicators of patient prognosis. Therefore, establishing corresponding standard assessment forms and admission criteria and preparing medical resources for critically ill patients is necessary as much as possible.
Early-onset Type 2 Diabetes Mellitus and Cardiometabolic Risk in India
Authors: Gupta Vipul , Khurana Girish 
Published: October 2023

Introduction:
The Indian patient phenotype with early-onset type 2 diabetes mellitus (T2DM) merits a more holistic understanding of the cardiometabolic risk profile. As per the principles of precision medicine, such understanding can help appraise the clinical place of interventions like sodium-glucose cotransporter-2 inhibition (SGLT2-i), for this population.

Methodology:
This observational study represents cases with T2DM, aged ≤40 years, who were newly initiated on empagliflozin on top of standard therapy. Analysis was performed for demographics and clinical characteristics at baseline and 3 months following empagliflozin use. Parameters for analysis included clinical and laboratory indicators of glycemic control, adiposity, insulin sensitivity, inflammation, and derived indicators for cardiometabolic risk. Descriptive statistics have been used for the analysis. Further, subgroups by body mass index (BMI) status (< or ≥25 kg/m2) have been compared for certain continuous variables, using an unpaired t-test.

Results:
The study included 70 patients, with a mean age of nearly 36 years. The mean BMI was 25.57 kg/m2; approximately 43% of patients had a BMI ≥25 kg/m2. The nonobese patients had a higher triglyceride-glucose index and lower fasting insulin levels, compared to obese patients. The risk of advanced nonalcoholic steatohepatitis was low in this population. The addition of empagliflozin to background therapy improved the HbA1c level by 1.21% with 44% goal-achievement and other metabolic parameters. Weight loss and anthropometric changes were modest. Empagliflozin use was associated with meaningful improvements in cardiometabolic parameters, including triglyceride-glucose index, atherogenic index of plasma, homeostatic model assessment for insulin resistance, quantitative insulin-sensitivity check index, visceral adiposity index, Fibrosis-4 index, and aspartate transaminase-to-platelet ratio index scores, in this population. Insulin resistance remained higher than normal in most patients, despite improvement with empagliflozin use over 3 months.

Conclusion:
The study findings for people with early-onset T2DM in India indicate: (1) the need for opportunistic screening for T2DM at an earlier age; (2) a high prevalence of insulin resistance regardless of obesity status; (3) meaningful improvements in overall cardiometabolic risk profile with SGLT2-i use; and (4) the importance of long-term optimization of diabetes care in this population.
Surgical and oncological outcomes of robot-assisted versus laparoscopic radical nephroureterectomy for upper-tract urothelial carcinoma: A single-center comparative analysis
Authors: Vasudeo Vivek , Singh Amitabh , Khanna Ashish , Rawal Sudhir Kumar , Pratihar Sarbartha Kumar , Saurabh Nikhil , Kumar Bhuwan , Ali Mujahid , Sharma Prerit , Akotkar Shravika , Sharma Girish , Kesarwani Bhagyashri 
Published: October 2023

ABSTRACT

Introduction:
We retrospectively compared surgical and oncological outcomes of robot-assisted (RA) radical nephroureterectomy (RNU) in patients of upper-tract urothelial carcinoma with a cohort of patients who underwent the same procedure using a laparoscopic approach.

Methods:
Data of 63 consecutive patients who underwent RNU with bladder cuff excision (BCE) from 2011 to 2022 at a single tertiary care institution was retrospectively retrieved from the electronically maintained institutional database. Twenty-six cases underwent RNU with a laparoscopic approach, whereas 37 were done by RA approach. Demographic, clinical, surgical, and pathologic details and survival analyses were reported and compared. The tetrafecta of RNU, which include the performance of a BCE, lymphadenectomy, no positive surgical margin, and no major surgical complication, was also reviewed.

Results:
The mean age and body mass index of the robotic and laparoscopic groups were 61.5 years versus 62.7 years and 23.8 versus 24.9 kg/m2, respectively (P = 0.710 and 0.309). The Charlson Comorbidity Index and upper-tract tumor site distribution were comparable between the groups. There was no significant difference in the distribution of T stage, N stage, presence of multifocality, or lymphovascular invasion between the two groups. Although the rate of concomitant carcinoma in situ was higher in laparoscopic cohort, 42.8% versus 10.8% in robotic cohort (P = 0.004). The laparoscopic group had higher blood transfusion rates (50 vs. 13.5%, P = 0.002) and longer median hospital stays (7 vs. 4 days, P = 0.000). The median follow-up time was 21.5 versus 27 months in the laparoscopic and robotic groups. The RA group was significantly better in the achievement of the tetrafecta outcomes. The 5-year urinary bladder recurrence-free survival (UB RFS) and elsewhere RFS between the laparoscopic and robotic cohorts were 65% versus 72% and 56% versus 70%, respectively (P = 0.510 and 0.190). The laparoscopic cohort had worse 5-year cancer-specific survival and overall survival (64% vs. 90% and 58% vs. 74%, P = 0.04 and 0.08).

Conclusion:
The robotic approach to RNU and BCE has significantly lower transfusion rates, lower hospital stays, and significantly better cancer-specific survival rates.
Prostate cancer detection using magnetic resonance imaging-transrectal ultrasound fusion biopsy: A retrospective cohort study
Authors: Pratihar Sarbartha Kumar , Khanna Ashish , Vasudeo Vivek , Gupta Rahul , Saurabh Nikhil , Kumar Bhuwan , Ali Mujahid , Akotkar Shravika S. , Rawal Sudhir Kumar , Singh Amitabh 
Published: October 2023

ABSTRACT

Introduction:
Transrectal ultrasound (TRUS) guided systematic prostate biopsy is conventionally used for the diagnosis of carcinoma prostate (CaP). However, magnetic resonance imaging (MRI) guided biopsies have been shown to have superior diagnostic performance. MRI-TRUS fusion biopsy improves the detection by combining the systematic and the targeted biopsies (TB). In this study, we evaluated the role of fusion biopsy in the detection of CaP as well as clinically significant carcinoma prostate (CsCaP).

Methods:
In this retrospective study, the patients who underwent fusion biopsy from January 2016 to July 2022 were evaluated. Patients underwent multiparametric MRI and the suspicious lesions were reported as per the Prostate Imaging Reporting and Data System (PIRADS) version 2. The clinical, imaging, and biopsy parameters were recorded and evaluated.

Results:
A total of 330 patients with PIRADS ≥3 underwent MRI-TRUS fusion biopsy and prostate cancer was detected in 187 patients (56.67%). With an increase in the PIRADS score, there was a significant rise in the detection of CaP (P < 0.001) and CsCaP (P < 0.0000001). Prostatitis was observed in 13%–18.1% of the patients with a lesion on MRI irrespective of the PIRADS score. The systematic and TB were comparable for the detection of CaP (P = 0.88) and CsCaP (P = 0.26). With a prostate-specific antigen density (PSAD) cutoff of 0.15 ng/mL/cc and 0.22 ng/mL/cc, biopsy could be safely avoided in 14.2% and 20.3% of the patients, missing only 0.3% of CaP and 0.9% of CsCaP, respectively. Different subgroups based on PSA levels, prostate volume, lesion dimension, and PIRADS score did not show a significant difference between the systematic and the targeted cores for the detection of CsCaP.

Conclusion:
This single center study of MRI-TRUS fusion prostate biopsy shows that in men with clinical suspicion of prostate cancer a pre-biopsy MRI and MRI-TRUS fusion combined systematic and targeted prostate biopsy improves the detection of prostate cancer and CsCaP. Patients with a PIRADS 3 lesion with a PSA density <0.22 can safely avoid prostate biopsy, without a significant risk of missing clinically significant prostate cancer.
Trends in reader access and article processing charges among urology journals: A systematic review
Authors: Uzun Hakki , Dil Eyüp , Akça Görkem , Özsagir Yusuf Önder , Sönmez Berat , Orman Erdem 
Published: October 2023

ABSTRACT

Introduction:
This bibliometric study is designed to investigate the relations of urology journals with access types and article processing charges (APCs) to assess the changing paradigm in urology publishing.

Methods:
The three major databases: The Master Journal List directory by Clavirate Analytics, Scopus® and PubMed were queried for relevant journals in urology and subspecialties. Characterization of urology journals was undertaken, and citation metrics and APCs were compared across access types. A partial sampling was used to investigate the number of open access (OA) articles according to access types and correlations with both APCs and CiteScore.

Results:
Seventy-seven journals were included into the study. Gold and diamond OA journals comprised 35.4% of urology journals in 2009 and were increased to 49.3% in 2022. No significant difference was found for change in the CiteScore of 2017 and 2021 between the access types, F (2,63) = 0.152, P = 0.859, η2 = 0.005. A moderate positive correlation was found between APCs and CiteScore for both hybrid (rs [27] =0.431, P < 0.0005) and gold OA (rs [27] =0.489, P = 0.007) journals. The authors need to pay $1175 more to publish their articles in OA model in hybrid journals. The number of articles published in OA model by hybrid journals were not correlated with APCs (rs = 0.332, P = 0.078) but correlated with CiteScore (rs = 0.393, P = 0.035).

Conclusions:
A paradigm shift in urology publishing toward OA model has been occurring. Authors choose prestige, OA model, rapid publication, and less rigorous peer-review to publish their articles. APCs bear only moderate correlation with the citation metrics of the urology journals.
Large functional retroperitoneal paraganglioma: A surgical challenge
Authors: Varty Gurudutt P , Patkar Shraddha , Goel Mahesh 
Published: October 2023

ABSTRACT
Paraganglioma is relatively rare retroperitoneal tumors. If functional retroperitoneal paragangliomas are misdiagnosed, surgical intervention can precipitate intraoperative hypertensive crises which may have serious consequences. We present a case of a 40-year-old female who presented with a large functional right-sided retroperitoneal paraganglioma encasing the inferior vena cava (IVC). The patient underwent paraganglioma excision with IVC resection with right nephrectomy. Such complex multivisceral resections require surgical expertise and are feasible at high-volume centers experienced in performing retroperitoneal surgeries.
Play therapy and storytelling intervention on children's social skills with attention deficit-hyperactivity disorder
Authors: Karbasi Amel Afsaneh , Rahnamaei Helia , Hashemi Zeinab 
Published: October 2023

BACKGROUND:
Attention deficit-hyperactivity disorder (ADHD) is a common neuro-behavioral disorder that negatively affects educational, relational, and occupational aspects of one's life. Although many children diagnosed with this disorder can benefit from taking medication, particularly for core symptoms, play therapy and storytelling can be seen as engaging, stimulating, and more compatible with children's developmental needs. The social skills of these children are as vital as other symptoms and can be better addressed with cognitive-based art therapy interventions. Because little research has been focused on the combination of play therapy and storytelling and the social interactions of children with ADHD are highly important in academic settings, this study aimed to determine the effects of this combination on children's social skills with ADHD.

MATERIALS AND METHODS:
This survey was a quasi-experimental study with a pre-test–post-test design and a control group. Participants were 7–11-year-old girls and boys with ADHD based on DSM-V referred to child and adolescent psychiatrists' clinics. Selected children were randomly allocated into intervention and control groups. The intervention group received an individual combined intervention of play therapy and storytelling, whereas the control group did not receive any therapeutic intervention for social skills at that time and was on the waiting list. The research tool was the Social Skills Rating System (SSRS), and data were computer-analyzed using SPSS-20 and a couple of descriptive and analytic tests including ANCOVA.

RESULTS:
In this study, 30 children with ADHD were included. The combined intervention of play therapy and storytelling has had a significant effect on post-test results of ADHD patients in terms of social skills as well as all test subscales (P < 0/05). There was a significant improvement in the subscales of self-expression, self-control, responsibility, and cooperation (P < 0.05).

CONCLUSIONS:
Results show promise for combined play therapy and storytelling intervention to enhance the social skills of elementary school children diagnosed with ADHD.
The effects of using the nurse self-concept mobile application on the retention of nursing students
Authors: Badiyepeymaiejahromi Zohreh , Bijani Mostafa , Taghizadeganzadeh Mahboobeh , Tehranineshat Banafsheh 
Published: October 2023

BACKGROUND:The high dropout rate among nursing students has become a global concern as it leads to a shortage of nurses on the one hand and a negative impact on the professional motivation of nursing students on the other. The present study was conducted to investigate the effects of using the Nurse Self-Concept Mobile Application (NSCMA) on the retention of nursing students.MATERIALS AND METHODS:The present study is an experimental work of research with a longitudinal design conducted from April to December 2021. The study population was second-year nursing students in a nursing school in the south of Iran who were randomly divided into an experimental (n= 49) and a control group (n= 50). The assessment was based on a pretest–posttest design and a one-month follow-up. The collected data were analyzed in SPSS v. 21 using descriptive statistics (frequency, percentage, mean, and standard deviation) and analytical statistics (repeated measures). ThePvalue was set <0.05.RESULTS:The means of the students' ages and grades were 21.31 ± 2.43 and 15.30 ± 2.13, respectively. The results showed a statistically significant increase in the experimental group's intent-to-stay mean scores as measured in three stages (P= 0.029), indicating that the intervention enhanced the nursing students' inclination to stay in nursing programs. However, the changes in the control group's mean scores were not statistically significant (P= 0.132).CONCLUSION:The Nurse Self-Concept Mobile Application proved effective in enhancing nursing students' inclination to complete their education and follow a career as a nurse. Thus, it is essential that nursing students' education include programs designed to enhance the students' self-concept, especially in the first few years of their education. Also, nursing schools should use this software to encourage students to stay in the nursing major.
Use of Massive Online Open Courses (MOOCs) model in virtual education development in first macro-region universities of medical sciences in countrywide territorial planning
Authors: Pouladi Ensieh , Taghvaee Yazdi Maryam , Salehi Mohammad , Moradi Siavash 
Published: October 2023

BACKGROUND:
Massive online open cources (MOOCs) are a new chapter in the topic of teaching–learning in higher education, which have been able to acquire a significant and valuable position in higher education and prestigious universities worldwide in line with the advancement of technology. The present study was conducted pursuing the goal to investigating the effect of use of MOOCs in the development of virtual education in universities of medical sciences in the first macro-region of countrywide territorial planning.

MATERIALS AND METHODS:
This research is based on a mixed method and practical in terms of purpose, and it was carried out in 2021 and 2022 in first macro-region of countrywide regional planning Medical Sciences Universities. The data of the qualitative section were converted into a questionnaire using the method of qualitative content analysis in a purposeful and semi-structured interview with 24 experts in the field of virtual education who had sufficient experience in the field of MOOC courses. The statistical population of the quantitative section is 1938 faculty members of the first macro-region of countrywide regional planning, of which 324 were selected by stratified random sampling. Its validity was calculated by Lawshe and Waltz–Bausell method by R software, and the reliability was calculated using Cronbach's alpha method with SPSS-21.

RESULTS:
Universities are facing challenges in structural, managerial, cultural, social, technological, and evaluation dimensions, and the current situation of using MOOCs in them is not appropriate.

CONCLUSION:
Besides, the analysis of the optimal situation of using MOOCs in these universities indicates that technological, structural, managerial, evaluation, educational, and personal dimensions are the most important in the effect of using MOOCs on the development of virtual education.
Conceptual explanation of adolescents' media health literacy: A qualitative content analysis
Authors: Daneshvar Samira , Ghaffari Mohtasham , Ramazankhani Ali , Marashi Tayebeh 
Published: October 2023

BACKGROUND:
The high use of media among adolescents is involved in negative social and health consequences. Therefore, it is critical that adolescents acquire the skills to interact with media content in a healthy way. This study aimed to identify the dimensions and concept of media health literacy (MHL) among adolescents.

MATERIALS AND METHODS:
In this qualitative study, specialists (n = 19) in the field of health education and promotion, as well as a wide range of activists in the field of media and communication and adolescents (n = 20), who met the inclusion criteria were participated in this study. Participants were recruited by purposive sampling. Exploratory, open-ended, and face-to-face interviews based on the interview guide were used to elicit participants' perspectives from October 2021 to May 2022 in Tehran, Iran. The interviews were analyzed by content analysis using the inductive method and MAXQDA 2020.

RESULTS:
A total of eight health education and promotion specialists (20.51%), nine media and communication specialists (23.07%), two software and programming instructors (5.12%), and 20 adolescents (51.28%) were included in the study. Analysis of qualitative data led to the identification of five categories (media literacy (ML), health literacy (HL), media reference, interactive communication literacy, and basic literacy (BL)) and 25 subcategories.

CONCLUSIONS:
Our findings provide a deep understanding of the concept and domains of MHL. Based on the results, MHL can be defined as a set of knowledge and individual skills needed in the fields of ML, HL, interactive communication literacy, media reference, and BL, which help achieve the appropriate state of MHL among adolescents and its improvement. It is hoped that these findings are used to guide the development of interventions for MHL.
Understanding the experiences of helplessness, fatigue and coping strategies among women seeking treatment for infertility – A qualitative study
Authors: Sambasivam Indra , Jennifer H. Gladius 
Published: October 2023

BACKGROUND:
Infertility impacts families and communities worldwide, affecting millions of people of reproductive age. The fertility rate in India is alarming. Fertility is valued in the majority of cultures, and having children is a fundamental motivation. The frustration and anger of an infertile woman affect her family, friends, and even her husband. This study aims to assess the factors that contribute to helplessness, fatigue, and coping strategies among women with infertility.

MATERIALS AND METHODS:
An in-depth interview was conducted among ten participants, to collect information about the challenges faced by women experiencing infertility. The participants were selected using a purposive sampling technique and they had at least 1 year of experience with infertility. A phenomenological study was utilized and themes and sub-themes were developed. Data was collected by using a list of probing open-ended questions and analyzed by colaizzi method.

RESULTS:
Women receiving infertility treatment over a long period of time disclosed that they are dealing with stressful situations in their lives. The experience left them feeling helpless in some stressful conditions. Due to a lack of both financial and emotional support from their family, when they are helpless, they are too worn out to continue their treatment. Some of these women are using different coping strategies to overcome their problems. We found seven common themes from this in-depth interview; 1) Lack of hope and support, 2) Spiritual resources, 3) Negative thoughts, 4) Social abstain, 5) Mental engagement, 6) Emotional concealment, and 7) Coping strategies.

CONCLUSION:
This study provides social, emotion and spiritual condition of infertile women in society. The majority of these women struggle with having negative thoughts due to a lack of support, concern, and involvement from their families. These results highlight the need to promote coping strategies, importance of financial and emotional support from the family members.