bluuebunny/crossref_metadata_2025_split huggingface dataset:
Possuo características empreendedoras? Uma análise com os alunos do bacharelado em administração do Instituição Federal do Piauí
Authors: De Sousa Filho Manoel Natalino , Carvalho Aline Kárem Santos , Rocha Ronielle Medeiros , De Morais Silvia Piva Rosal , Dourado André de Sousa , Toscano Thais Sales Barreto , Veras Sabrina Maria Parente , De Moura Ana Gabriella Moreira , Silva Poena Livia Bonfim 
Published: December 2023

O empreendedorismo pode ser considerado um fenômeno econômico influente, ou seja, é atualmente um dos principais fatores para o desenvolvimento da economia de um país, dessa forma é fundamental que se tenha um panorama acerca de suas características e de seu crescimento. Nesse contexto, o presente trabalho busca analisar as características empreendedoras nos estudantes de administração do instituto Federal do Piauí. Possui uma abordagem quantitativa, utilizando o método Survey. A pesquisa foi aplicada na microrregião dos Cocais no Piauí, especialmente em dois campi de uma instituição de ensino superior. A população alvo da pesquisa conta com 308 alunos devidamente matriculados nos cursos de bacharelado em administração, obtendo-se um total de 162 respostas válidas. O instrumento de coleta dos dados utilizado foi um questionário que contempla as características comportamentais empreendedoras (CCE’s), desenvolvido por McClelland. Os dados foram coletados por meio da aplicação do questionário no formato presencial, contando com 55 questões na escala tipo likert de cinco pontos. Os resultados obtidos mostram que os estudantes da instituição demonstram possuir todas as características empreendedoras presente, isso pode ser resultado de uma boa qualidade da educação na qual os mesmos são expostos na instituição, entretanto foi observado que as características persuasão e redes de contatos e independência e autoconfiança se apresentam de forma inferior às demais.
Desempenho da iluminância das salas de aulas em uma instituição de ensino superior: um caso da Universidade Federal do Piauí
Authors: Almeida Matheus das Neves , Da Silva Alana Alves , Dias Érico Rego , Mota Francisco de Assis da Silva , Caselli Francisco de Tarso Ribeiro , De Medeiros Nayara Cardoso , Leitão Antonio Bruno de Vasconcelos , Pereira Geordy Souza , Teles Francismilton 
Published: December 2023

Um dos 17 Objetivos de Desenvolvimento Sustentável propostos pelas Nações Unidas para a agenda 2030 é a Educação de Qualidade. Para alcançar esse objetivo, o conforto luminoso considerado na Qualidade Ambiental Interior, tem uma parcela significativa na Educação de Qualidade. Nesta pesquisa, buscou-se avaliar o desempenho da iluminância média () das salas de aulas em uma universidade. Portanto, selecionou-se dez salas de aulas e mensurou-se nos três turnos, utilizando um luxímetro LDR-225. Em seguida, com o software RStudio, resumiu-se os dados em medidas centrais e dispersão para compará-los com a norma NBR ISO/CIE 8995-1. Posteriormente, executou-se os testes Shapiro Wilke e Lillitefors, a fim de averiguar se os são normais e o teste Wilcoxon, para saber se as médias são iguais. Os resultados indicaram que as salas obtiveram um lux e, assim, atendem aos valores mínimos normalizados para os turnos manhã e tarde. No entanto para a noite, a norma fixa lux e as salas obtiveram valores entre lux, sendo incoerentes com a norma. Além disso, verificou-se que há diferenças significativas entre as médias dos turnos e que a média da noite foi inferior as demais. Outra diferença observada, foi que a sala 2 obteve um desempenho médio diferente de sete salas cujos layouts são iguais. Contudo, a diferença e inferioridade entre o turno da noite com os demais pode ser um indício de que a luz natural influencia no desempenho e que a sala 2 pode estar necessitando de manutenção ou troca de lâmpadas.
Influence of Biochar and Irrigation Levels on Productivity of Marjoram (Origanum majorana L.) under Sandy Soil Conditions
Authors: Hassan Reem H. I. , Abbas S. M. T.  , Ismail A. Y.  
Published: December 2023

A field experiment designed as a split-plot experiment based on a randomized complete block design with three replications was conducted during two summer successive seasons 2021 and 2022 at the Experimental Farm of EL-Quassasin Horticultural Research Station, Ismailia Governorate; Egypt, to investigate the influence of biochar at rates of 0, 2, 4, and 6 tons/fed. at three irrigation levels (1, 1.5, and 2 hours/day) using a drip irrigation system on the growth, essential oil (productivity and constituents), as well as some chemical constituents of marjoram (Origanum majorana L.) plant grown in sandy soil. The obtained results revealed that both irrigation and biochar levels affected all the above-mentioned traits. It was clear that plant growth parameters increased as long as increasing irrigation levels and biochar rate. Considering the interaction, it was clear that generally the highest values in vegetative growth (plant height, number of branches, and herb fresh & dry weights/ plant), essential oil yield/plant, N%, and K% were attained from the treatment of irrigation at 1.5 hours/day combined with biochar at the rate of 6ton/fed. On the other hand, the highest values of essential oil%, essential oil components (p-cymene, trans-Sabinene hydrate, α-terpineol), as well as proline, were recorded in stressed plants (received 1h/ day irrigation and 0 biochar). The existing outcomes show that biochar application might increase water use efficiency and produce a high yield of marjoram. Subsequently, it could be a viable option to alleviate the severity effect of water deficit in marjoram growth, which opens opportunities for cultivating arid regions.
Characterization of Buffelgrass (Cenchrus ciliaris L.) Germplasm Using DUS Descriptors
Authors: Hemavathy A. Thanga , Subramanian A. , Anantharaju P. , Sakila M. , Kavitha S. 
Published: December 2023

The present study was carried on thirty seven Cenchrus genotypes during rabi, 2022-23. Tweleve traits were recorded as per the descriptors provided by PPV & FRA and several genotypes possessed unique traits that aids in genotype identification. The traits viz.,Growth habit ,Anothcyanin coloration on nodes, Node colour, Leaf blade altitude, Leaf blade pubescence, Awns distribution, Awns colour, Leaf colour, and Early vigour showed significant variation among genotypes. Quantitative Characters viz., Plant height, Leaf length (cm), Leaf width (cm), Inter-nodal length (cm), Nodes on tiller, Panicle length (cm), Tillers/Plant, Green fodder yield were recorded. The traits, Plant height, No. of tillers plant and green fodder yield recorded significant critical difference between the genotypes. Hence utmost care would be given for these characters while in the selection process of Cenchrus ciliaris crop improvement.
Association of plasma sPD‐1 and sPD‐L1 with disease status and future relapse in AQP4‐IgG (+) NMOSD
Authors: Liu Jia , Shao Xi , Fan Jingya , Wang Ying , Cao Yuanbo , Tan Guojun , Sugimoto Kazuo , Li Bin , Jia Zhen 
Published: December 2023

AbstractObjectiveNeuromyelitis optica spectrum disorder (NMOSD) is an autoimmune‐mediated disorder with aquaporin 4‐immunoglobulin G (AQP4‐IgG) in most settings. Soluble programmed death‐1 (sPD‐1) and soluble programmed death ligand 1 (sPD‐L1) play key roles in immunomodulation. We aim to assess the association of sPD‐1 and sPD‐L1 with cytokines and their clinical significance in AQP4‐IgG (+) NMOSD.MethodWe measured plasma sPD‐1, sPD‐L1, and 10 cytokines levels of 66 AQP4‐IgG (+) NMOSD patients, including 40 patients in attack (attack‐NMOSD) and 26 patients in remission (remission‐NMOSD) phases, and 28 healthy controls through ultrasensitive Simoa and SP‐X platform, respectively. We also performed >2 years (median) of follow‐up after testing and analyzed the relationship between the detection index and current and future clinical parameters.ResultPlasma sPD‐1 level discriminated attack‐NMOSD from remission‐NMOSD (AUC = 0.692, p = 0.009). sPD‐1 and sPD‐L1 levels positively correlated with IL‐6 (rsPD‐1 = 0.313; rsPD‐L1 = 0.508), IFN‐γ (rsPD‐1 = 0.331; rsPD‐L1 = 0.456), and TNF‐α (rsPD‐1 = 0.451; rsPD‐L1 = 0.531) expression, as well as clinical indicators, including the EDSS score (rsPD‐1 = 0.331; rsPD‐L1 = 0.402), number of attacks (rsPD‐1 = 0.431) and segments of spinal cord involvement (rsPD‐1 = 0.462; rsPD‐L1 = 0.508). The risk of relapse within 2 years after sampling was associated with higher sPD‐1/sPD‐L1 ratio in attack‐NMOSD (p = 0.022; Exp(B) = 1.589).InterpretationPlasma sPD‐1 and sPD‐L1 levels reflected current disease severity and activity, and predicted future relapses in AQP4‐IgG (+) NMOSD, suggesting that they hold the potential to guide timely and targeted treatment.
Renoprotective Effects of Mineralocorticoid Receptor Antagonists Against Diabetic Kidney Disease
Authors: Bayne Sarah , LeFevre James , Olstinske Kayla , Ravindran Sreenithya , Munusamy Shankar 
Published: December 2023

AbstractDiabetic kidney disease (DKD) is a growing epidemic worldwide and a leading cause of end‐stage kidney disease. Mineralocorticoid receptor (MR) blockade using Finerenone is a recently approved therapeutic approach to slow down the progression of DKD in patients with type 2 diabetes in addition to other therapies such as angiotensin‐II converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), sodium‐glucose co‐transporter 2 (SGLT2) inhibitors, and glucagon‐like peptide 1 (GLP‐1) analogs. This review elaborates on the pathophysiologic pathways activated by aldosterone (the human mineralocorticoid) in DKD, the pharmacology of three different generations of mineralocorticoid receptor antagonists (MRAs), specifically, spironolactone, eplerenone, and finerenone, and the mechanisms by which these MRAs elicit their protective effects on the kidney under diabetic settings.
Approaching the Robust Linearity in Dual‐Floating van der Waals Photodiode
Authors: Xu Jinpeng , Luo Xiaoguang , Lin Xi , Zhang Xi , Liu Fan , Yan Yuting , Hu Siqi , Zhang Mingwen , Han Nannan , Gan Xuetao , Cheng Yingchun , Huang Wei 
Published: December 2023

AbstractTwo‐dimensional (2D) material photodetectors have gained great attention as potential elements for optoelectronic applications. However, the linearity of the photoresponse is often compromised by the carrier interaction, even in 2D photodiodes. In this study, a new device concept of dual‐floating van der Waals heterostructures (vdWHs) photodiode is presented by employing ambipolar MoTe2 and n‐type MoS2 2D semiconductors. The presence of type II heterojunctions on both sides of channel layers effectively depletes carriers and restricts the photocarrier trapping within the channel layers. As a result, the device exhibits robust linear photoresponse under photovoltaic mode from the visible (405 nm) to near‐infrared (1600 nm) band. With the built‐in electric field of the vdWHs, a linear dynamic range of ≈100 dB, responsivity of ≈1.57 A W−1, detectivity of ≈4.28 × 1011 Jones, and response speed of ≈30 µs are achieved. The results showcase a promising device concept with excellent linearity toward fast and low‐loss detection, high‐resolution imaging, and logic optoelectronics.
A Drug‐Mineralized Hydrogel Orchestrated by Spontaneous Dynamic Mineralization
Authors: Liu Jiaying , Zhang Xiaonong , Xiao Chunsheng , Chen Xuesi 
Published: December 2023

AbstractFabrication of mineralized materials through the nature‐mimicking dynamic biomineralization process has attracted great interest but remains a huge challenge till now. Here, a drug‐mineralized hydrogel (DMH) with spontaneous dynamic mineralization behaviors is reported, which highly mimics the dynamic mineralization process of natural tissues. The hydrogel is facilely fabricated via directly mixing sodium hyaluronate (HA) with alendronate sodium (ADA) and CaCl2 in deionized water. The resultant hydrogel possesses a white‐to‐semi‐transparent transition and a soft‐to‐hard transition during incubation at 37 °C. Mechanism studies reveal that the spontaneous dynamic change of the hydrogel is ascribed to the HA‐regulated dynamic mineralization of ADA/Ca2+ complexes, where amorphous ADA/Ca2+ complexes will gradually transform into mineral crystals with the prolongation of incubation time. Owing to the dynamic transformation process, the DMH shows excellent injectability and moldability at the initial stage. More importantly, the DMH exhibits a sustained release behavior of ADA in vitro, superior adhesiveness with bone, biodegradability, and good biocompatibility. As a result, the developed DMH demonstrates promising uses for accelerating bone repair in a rat cranial defect model. Overall, the research provides a general strategy to prepare drug‐mineralized hydrogels with spontaneous dynamic mineralization behaviors, which may find potential uses in various biomedical fields.
A Dual‐Function Hemicyanine Material with Highly Efficient Photothermal and Photodynamic Effect Used for Tumor Therapy
Authors: Zhang Minglu , Wang Shuo , Bai Yueping , Wang Danyang , Fu Yu , Su Zongyi , Zhang Guoqiang , Meng Meng , Yu Fan , Wang Bing , Jin Hongzhen , Zhao Wei 
Published: December 2023

AbstractSmall molecular organic optical agents with synergistic effects of photothermal therapy (PTT) and photodynamic therapy (PDT), hold credible promise for anti‐tumor therapy by overcoming individual drawbacks and enhancing photon utilization efficiency. However, developing effective dual‐function PTT‐PDT photosensitizers (PSs) for efficient synergistic phototherapy remains challenging. Here, a benz[c,d]indolium‐substituted hemicyanine named Rh‐BI, which possesses a high photothermal conversion efficiency of 41.67% by exhaustively suppressing fluorescence emission, is presented. Meanwhile, the rotating phenyl group at meso‐site induces charge recombination to enhance the molar extinction coefficient up to 13.58 × 104 M−1cm−1, thereby potentiating the photodynamic effect. Under 808 nm irradiation, Rh‐BI exhibits significant phototoxicity in several cancer cell types in vitro with IC50 values as low as ≈0.5 µM. Moreover, treatment of 4T1 tumor‐bearing mice with Rh‐BI under laser irradiation successfully inhibits tumor growth. In a word, an effective strategy is developed to build PTT‐PDT dual‐functional optical materials based on hemicyanine backbone for tumor therapy by modulating conjugation system interaction to adjust the energy consumption pathway.
A Butterfly‐Inspired Multisensory Neuromorphic Platform for Integration of Visual and Chemical Cues
Authors: Zheng Yikai , Ghosh Subir , Das Saptarshi 
Published: December 2023

AbstractUnisensory cues are often insufficient for animals to effectively engage in foraging, mating, and predatory activities. In contrast, integration of cues collected from multiple sensory organs enhances the overall perceptual experience and thereby facilitates better decision‐making. Despite the importance of multisensory integration in animals, the field of artificial intelligence (AI) and neuromorphic computing has primarily focused on processing unisensory information. This lack of emphasis on multisensory integration can be attributed to the absence of a miniaturized hardware platform capable of co‐locating multiple sensing modalities and enabling in‐sensor and near‐sensor processing. In this study, this limitation is addressed by utilizing the chemo‐sensing properties of graphene and the photo‐sensing capability of monolayer molybdenum disulfide (MoS2) to create a multisensory platform for visuochemical integration. Additionally, the in‐memory‐compute capability of MoS2 memtransistors is leveraged to develop neural circuits that facilitate multisensory decision‐making. The visuochemical integration platform is inspired by intricate courtship of Heliconius butterflies, where female species rely on the integration of visual cues (such as wing color) and chemical cues (such as pheromones) generated by the male butterflies for mate selection. The butterfly‐inspired visuochemical integration platform has significant implications in both robotics and the advancement of neuromorphic computing, going beyond unisensory intelligence and information processing.
Ultrathin Van der Waals Lanthanum Oxychloride Dielectric for 2D Field‐Effect Transistors
Authors: Li Linyang , Dang Weiqi , Zhu Xiaofei , Lan Haihui , Ding Yiran , Li Zhu‐An , Wang Luyang , Yang Yuekun , Fu Lei , Miao Feng , Zeng Mengqi 
Published: December 2023

AbstractDownsizing silicon‐based transistors can result in lower power consumption, faster speeds, and greater computational capacity, although it is accompanied by the appearance of short‐channel effects. The integration of high‐mobility 2D semiconductor channels with ultrathin high dielectric constant (high‐κ) dielectric in transistors is expected to suppress the effect. Nevertheless, the absence of a high‐κ dielectric layer featuring an atomically smooth surface devoid of dangling bonds poses a significant obstacle in the advancement of 2D electronics. Here, ultrathin van der Waals (vdW) lanthanum oxychloride (LaOCl) dielectrics are successfully synthesized by precisely controlling the growth kinetics. These dielectrics demonstrate an impressive high‐κ value of 10.8 and exhibit a remarkable breakdown field strength (Ebd) exceeding 10 MV cm−1. Remarkably, the conventional molybdenum disulfide (MoS2) field‐effect transistor (FET) featuring a dielectric made of LaOCl showcases an almost negligible hysteresis when compared to FETs employing alternative gate dielectrics. This can be attributed to the flawlessly formed vdW interface and excellent compatibility established between LaOCl and MoS2. These findings will motivate the further exploration of rare‐earth oxychlorides and the development of more‐than‐Moore nanoelectronic devices.
Influence of Annealing on Thin Film/Substrate Interface and Vacuum Ultraviolet Photoconductivity of Neodymium Fluoride Thin Films
Authors: Kato Tomoki , Cadatal‐Raduban Marilou , Horiuchi Yusuke , Ozawa Gakuto , Ono Shingo 
Published: December 2023

AbstractHigh photon energy vacuum ultraviolet radiation (VUV, 100−200 nm wavelength) is challenging to detect. It easily degrades conventional silicon and semiconductor photodetectors. Fluoride photodetectors can be the answer, but the correlation between fabrication parameters and photodetector performance is not known. Here, the effect of annealing is investigated on the characteristics of neodymium trifluoride thin film/quartz substrate interface and NdF3 photoconductivity within the VUV. Thin films are deposited on unheated and heated (600 °C) substrates with post‐deposition annealing. Dark current of films on unheated substrates decreases by as much as 1/10 as resistance increases from 1 −12 TΩ after annealing. Dark current of films on heated substrates increases even after annealing, resulting in similar photo and dark currents of ≈303.7 nA and poor detectors. Fluorine diffuses from the film to the substrate during deposition, exacerbated by substrate heating but not by annealing. Fluorine diffusion degrades crystallinity near the interface, increasing the dark current. Fluorine diffusion is absent when MgF2 is used as the heated substrate. Unannealed NdF3/MgF2 detector on 600 °C‐heated substrate and 600 °C‐annealed NdF3/SiO2 detector on unheated substrate exhibit similar resistances of ≈14 TΩ. Considering the film/substrate interface and annealing is crucial when developing VUV photodetectors.
Top‐Down Fabrication of Ordered Nanophotonic Structures for Biomedical Applications
Authors: Wen Baohua , Yang Ji , Hu Chao , Cai Jingxuan , Zhou Jianhua 
Published: December 2023

AbstractThe size, distribution, and specific shape of ordered nanophotonic structures are crucial for their biomedical applications. Bottom‐up approaches such as self‐assembly, emulsification, and precipitation are commonly fabricated nanophotonic structures, which often lack control of nanophotonic structures morphologies and monodispersed sizes. On the contrary, top‐down nanofabrication techniques offer the advantages of high fidelity and high controllability and are employed in the fabrication of nanophotonic structures. This review focuses on top‐down nanofabrication techniques to fabricate ordered nanophotonic structures and their biomedical applications. Several top‐down approaches used in the semiconductor industry and other fields requiring micro‐ and nanopatterns are used, including electron beam lithography/ion beam lithography, photolithography, interference lithography, nanoimprint lithography, nanosphere lithography, nanotransfer lithography, and nano‐electrodeposition. Various current and emerging biomedical applications of the ordered nanophotonic structures are also covered: i) surface‐enhanced Raman scattering, ii) plasmonics, including surface plasmon resonance and localized surface plasmon resonance, and iii) fluorescence enhancement. Finally, a future perspective of nanophotonic structures fabricated by top‐down techniques in biomedical applications is also summarized.
Visible Light‐Induced EDA‐Complex Triggered Annulative Difunctionalization via Olefin‐Olefin Coupling and Radical Truce‐Smiles Rearrangement
Authors: Mondal Karunamayee , Baidya Mahiuddin 
Published: December 2023

AbstractAn EDA complex comprisingN‐allyl bromodifluoroacetamides and tertiary alkyl amine was exploited to facilitate annulative difunctionalization reaction under visible‐light irradiation. This external photocatalyst‐free methodology garners olefin‐olefin coupling featuring a radical Truce‐Smiles rearrangement and produced long‐chain functionalizedgem‐difluoropyrrolidones fromN‐substituted methacryloyl sulfonamides, while simpleN‐aryl methacrylamides furnished pyrrolidinone‐oxindole hybrid lactams in high yields. Mechanistic investigations substantiate a combined reaction mechanism, involving charge‐transfer EDA complex‐based radical cascade, alongside an α‐aminoalkyl radical‐triggered XAT process, exhibiting a quantum yield value of 1.48.
Visible Light instead of Transition Metal: Electron Donor Acceptor Complex Enabled Cross‐Coupling of Aryl Halides with Active Methylene Compounds
Authors: Volkov Alexey A. , Bugaenko Dmitry I. , Karchava Alexander V. 
Published: December 2023

AbstractAn arylation of anions of active methylene compounds with aryl halides provides an access to synthetically versatile α‐arylated 1,3‐diketones, β‐keto esters, β‐keto nitriles, β‐cyano esters, etc. Previously, these C−C cross‐coupling reactions have been accomplished only using transition metal‐based catalysts. Herein, we demonstrate that these arylations can be successfully realized under catalyst‐free conditions employing the electron donor‐acceptor (EDA) complex photoactivation strategy. The protocol was further optimized for a semi‐one pot synthesis of indole derivatives via an intramolecular C−C coupling.
Copper Modulated Lead‐Free Cs4MnSb2Cl12 Double Perovskite Microcrystals for Photocatalytic Reduction of CO2
Authors: Gao Bo , Tian Changqing , Guo Linfeng , Zhou Jinchen , Wang Zixian , Fu Chengfan , Ran Hongmei , Chen Wei , Huang Qiang , Wu Daofu , Tang Xiaosheng , Luo Zhongtao 
Published: December 2023

AbstractIn order to deal with the global energy crisis and environmental problems, reducing carbon dioxide through artificial photosynthesis has become a hot topic. Lead halide perovskite is attracted people's attention because of its excellent photoelectric properties, but the toxicity and long‐term instability prompt people to search for new photocatalysts. Herein, a series of <111> inorganic double perovskites Cs4Mn1‐xCuxSb2Cl12 microcrystals (x = 0, 0.1, 0.2, 0.3, 0.4, and 0.5) are synthesized and characterized. Among them, Cs4Mn0.7Cu0.3Sb2Cl12 microcrystals have the best photocatalytic performance, and the yields of CO and CH4 are 503.86 and 68.35 µmol g−1, respectively, after 3 h irradiation, which are the highest among pure phase perovskites reported so far. In addition, in situ Fourier transform infrared (FT‐IR) spectroscopy and electron spin resonance (ESR) spectroscopy are used to explore the mechanism of the photocatalytic reaction. The results highlight the potential of this class of materials for photocatalytic reduction reactions.