bluuebunny/crossref_metadata_2025_split huggingface dataset:
Customizable Scintillator of Cs3Cu2I5:2% In+@Paper for Large‐Area X‐Ray Imaging
Authors: Chen Weiqing , Wang Ting , Wang Tianchi , Yu Jing , Yao Shuyi , Feng Wei , Wang Qingyuan , Huang Ling , Xu Xuhui , Yu Xue 
Published: October 2023

AbstractHigh‐resolution X‐ray imaging is increasingly required for medical diagnosis and large‐area detection. However, the issues of scattering and optical crosstalk are limiting the spatial resolution of the indirect X‐ray imaging. In this study, a feasible and efficient strategy is proposed to in situ synthesize flexible Cs3Cu2I5:2%In+@paper as a superior scintillator film, which can be scaled up to an ultra‐large area of 4800 cm2. The as‐obtained Cs3Cu2I5:2%In+@paper performs a fascinating photoluminescence quantum efficiency up to 88.14%, a steady state light yield of 70169 photons/MeV, and spatial resolution of 15 lp mm−1. Moreover, the suppressed physical scattering and optical crosstalk of the corresponding film are demonstrated. Accordingly, this work explores a feasible fabrication of customizable scintillation films with large area for high‐resolution X‐ray detection.
Approaching the Zero‐Power Operating Limit in a Self‐Coordinated Organic Protonic Synapse
Authors: Liu Shuzhi , He Zhilong , Zhang Bin , Zhong Xiaolong , Guo Bingjie , Chen Weilin , Duan Hongxiao , Tong Yi , He Haidong , Chen Yu , Liu Gang 
Published: October 2023

AbstractHigh‐performance artificial synapse with nonvolatile memory and low power consumption is a perfect candidate for brainoid intelligence. Unfortunately, due to the energy barrier paradox between ultra‐low power and nonvolatile modulation of device conductances, it is still a challenge at the moment to construct such ideal synapses. Herein, a proton‐reservoir type 4,4′,4″,4'''‐(Porphine‐5,10,15,20‐tetrayl) tetrakis (benzenesulfonic acid) (TPPS) molecule and fabricated organic protonic memristors with device width of 10 µm to 100 nm is synthesized. The occurrence of sequential proton migration and interfacial self‐coordinated doping will introduce new energy levels into the molecular bandgap, resulting in effective and nonvolatile modulation of device conductance over 64 continuous states with retention exceeding 30 min. The power consumptions of modulating and reading the device conductance approach the zero‐power operating limits, which range from 16.25 pW to 2.06 nW and 6.5 fW to 0.83 pW, respectively. Finally, a robust artificial synapse is successfully demonstrated, showing spiking‐rate‐dependent plasticity (SRDP) and spiking‐timing‐dependent plasticity (STDP) characteristics with ultra‐low power of 0.66 to 0.82 pW, as well as 100 long‐term depression (LTD)/potentiation (LTP) cycles with 0.14%/0.30% weight variations.
Effective Thermal Properties of a HTS Transition Edge Bolometer for High‐Flux Neutron Detection
Authors: Brock Mette Bybjerg , Østergaard Emil Visby , Wulff Anders C. , Abrahamsen Asger Bech , Kuhn Luise Theil 
Published: October 2023

AbstractMany applications require monitoring of increasingly high neutron flux levels. Pre‐neutron characterization is performed of a superconducting transition edge bolometric device, sensitive to neutrons by an enriched boron carbide (10B4C) layer. Heat from the absorption of neutrons is simulated using an attenuated laser, while the detector is cooled to the critical temperature,Tc. Frequency dependent (4–25 Hz) and constant input power measurements are performed on a10B4C‐coated and a non‐coated pixel. Results are used to fit a two lumped element thermal model. The effective specific heat is highly dependent on the input pulse duration due to the interconnected stack structure. For modulated pulses, the active volume in the thermal circuit is the full depth of the substrate in the area under the pixel. For constant power input, a large portion of the substrate is heated and the interface conductivities to the cold finger are found to be important. The detectivity is D* = 3.5 × 108 , and is only slightly lower than similar detectors. Understanding the dynamics of the detector better and using neutron excitation, it is expected that optimizations can lead to an equally good detector for cold to thermal neutrons at flux levels >106 n cm−2s−1.
Fully Screen‐Printed Perovskite Solar Cells with 17% Efficiency via Tailoring Confined Perovskite Crystallization within Mesoporous Layer
Authors: Chen Changshun , Ran Chenxin , Guo Chunyu , Yao Qing , Wang Jinpei , Niu Tingting , Li Deli , Chao Lingfeng , Xia Yingdong , Chen Yonghua 
Published: October 2023

AbstractUsing a screen‐printing techniques is thought to be a good candidate for simplified, cost‐effective, reliable, and scalable fabrication of fully printed perovskite solar cells (PSCs) for industrialization. Nevertheless, the screen‐printing of perovskite film has not been realized until recently. This group finished the work using ionic liquid methylamine acetate (MAAc) as pure solvent. However, the space‐confining effect during the perovskite crystallization in mesoporous impeded the escape of bottom MAAc molecules, which leads to the poor crystalline quality of the screen‐printed film. In this work, ionic liquid methylamine propionate (MAPa) with stronger coordination is introduced as a co‐solvent to promote the escape of MAAc molecules by forming the solvent volatilization channels in a confined mesoporous structure, which results in the complete MAAc volatilization and high filling degree of perovskite crystals inside the mesoporous structure. Also, MAPa promotes the vertical growth of perovskite crystals and coordinates with unbonded Pb2+ on the perovskite surface, leading to efficient charge transport and interfacial band alignment of the screen‐printed film. Finally, fully screen‐printed PSCs yields a champion power conversion efficiency (PCE) of ≈17%, which is the record value for fully screen‐printed PSCs. Moreover, the unencapsulated device shows robust operational stability that maintains >85.3% of initial PCE (25%RH and 25 °C) under continuous illumination at the maximum power point after 250 h.
Psychopharmacological treatments in Down syndrome and autism spectrum disorder: State of the research and practical considerations
Authors: Baumer Nicole T. , Capone George 
Published: October 2023

AbstractIndividuals with Down syndrome (DS) or Autism Spectrum Disorder (ASD), and especially those with both DS and co‐occurring ASD (DS + ASD) commonly display behavioral and psychiatric symptoms that can impact quality of life and places increased burden on caregivers. While the mainstay of treatment in DS and ASD is focused on educational and behavioral therapies, pharmacological treatments can be used to reduce symptom burden. There is a paucity of evidence and limited clinical trials in DS and DS + ASD. Some scientific evidence is available, primarily in open label studies and case series that can guide treatment choices. Additionally, clinical decisions are often extrapolated from evidence and experience from those with ASD, or intellectual disability in those without DS. This article reviews current research in pharmacological treatment in DS, ASD, and DS + ASD, reviews co‐occurring neurodevelopmental and mental health diagnoses in individuals with DS + ASD across the lifespan, and describes practical approaches to psychopharmacological management.
Assessment of the in Vitro Antimelanoma Potential of Lippia microphylla Cham (Verbenaceae) Essential Oil
Authors: de Oliveira Lopes Ana Luiza , Neves de Andrade Camyla Caroliny , Sousa Duarte Sâmia , Gadelha Marques Karinne Kelly , Ramos Marques de Souza Ramon , de Lourdes Assunção Araújo de Azevedo Fátima , Fechine Tavares Josean , dos Santos Golzio Sócrates , Ramos Gonçalves Juan Carlos , Sobral Marianna Vieira 
Published: October 2023

AbstractEssential oils stand out among natural products for their complex composition, frequently described in the literature with a range of biological effects. This study evaluated the cytotoxic activity against several human cancer cell lines of essential oils extracted from the leaves of Lippia microphylla (EO‐LM) Cham. (Verbenaceae). The melanoma cell line SK‐MEL‐28 was the most sensitive to the EO‐LM, presenting an IC50 of 33.38±1.16 μg/mL. Afterward, the effects of EO‐LM on the cell cycle, induction of apoptosis, and production of reactive oxygen species (ROS) were evaluated. We stated a significant increase in the sub‐G1 population, indicating apoptosis, later confirmed by an increase of SK‐MEL‐28 cells labeled with Annexin V‐FITC and by the formation of apoptotic bodies and membrane blebs, observed by confocal microscopy. Additionally, EO‐LM reduced the production of ROS, indicating antioxidant activity. Therefore, EO‐LM exhibits anti‐melanoma activity in vitro, suggesting its potential as an anticancer agent.
Hierarchical Porous Aerogels With Multiple Adsorptive Interactions for Dye Wastewater Purification
Authors: Gao Yang , Xu Zikai , Ren Xiuyan , Gao Guanghui 
Published: October 2023

AbstractAerogels present a huge potential for removing organic dyes from printing and dyeing wastewater (PDW). However, the preparation of aerogels with multiple dye adsorption capabilities remains a challenge, as many existing aerogels are limited to adsorbing only a single type of dye. Herein, a composite aerogel (CG/T‐rGO) with the addition of carboxymethyl chitosan, gelatin and tannic acid reduced graphene oxide (T‐rGO) was synthesized by freeze‐drying technology. The electrostatic interactions between dye molecular and GEL/CMCS (CG) networks, as well as the supramolecular interactions (H‐bonds, electrostatic interactions and π–π stacks) between T‐rGO, have endowed the aerogel with the ability to adsorb multiple types of dye, such as methylene blue (MB) and methyl orange (MO). Results exhibited that the prepared CG/T‐rGO aerogel possessed strong mechanical strength and a porous 3D network structure with a porosity of 96.33 %. Using MB and MO as adsorbates, the adsorption capacity (88.2 mg/g and 66.6 mg/g, respectively) and the mechanism of the CG/T‐rGO aerogel were investigated. The adsorption processes of aerogel for MB and MO were shown to follow the pseudo‐second‐order kinetic model and Langmuir isotherm model, indicating the chemical adsorption of a monolayer. The proposed aerogel in this work has promising prospects for dye removal from PDW.
Mechanochemical Scholl Reaction on Phenylated Cyclopentadiene Core: One‐Step Synthesis of Fluoreno[5]helicenes
Authors: Báti Gábor , Csókás Dániel , Stuparu Mihaiela C. 
Published: October 2023

AbstractIn this study, we explore feasibility of the mechanochemical approach in the synthesis of tetrabenzofluorenes (fluoreno[5]helicenes). For this, commercially available phenylated cyclopentadiene precursors are subjected to the Scholl reaction in the solid state using FeCl3 as an oxidant and sodium chloride as the solid reaction medium. This ball milling process gave access to the 5‐membered ring containing‐helicenes in one synthetic step in high (95–96 %) isolated yields. The solution‐phase reactions, however, were found to be moderate to low yielding in this regard (10–40 %).
Durable and dramatic response to checkpoint inhibition combined with COX‐2 inhibitor celecoxib in a patient with p16+ metastatic sinonasal undifferentiated carcinoma: A case study
Authors: Trinh Jonathan Q. , Acosta Cassaundra , Easwar Arti , Galamaga Robert , Tan Alan 
Published: October 2023

AbstractBackgroundSinonasal undifferentiated carcinoma (SNUC) is an exceedingly rare head and neck malignancy. No consensus exists on treatment for metastatic disease.CaseA 56‐year‐old female was diagnosed with SNUC after endorsing sinus congestion, diplopia, and right orbital pain. Initially treated with surgery and radiation, she later developed significant metastatic disease. She demonstrated progression of her hepatic metastases under pembrolizumab therapy. However, the addition of ipilimumab and a COX‐2 inhibitor resulted in significant improvement in her lesions as well as an ongoing durable response. Her regimen was complicated by immune‐related adverse events successfully treated with steroids.ConclusionDual checkpoint inhibition deserves consideration when treating metastatic SNUC, especially after single agent therapy has failed. The positive effect of this treatment may be augmented by IDO1 inhibition.
ERSChain: Towards secure and flexible educational resource sharing using consortium blockchain and revocable ciphertext‐policy attribute‐based encryption
Authors: Zhao Gang , He Hui , Di Bingbing , Wu Tong 
Published: October 2023

SummarySharing high‐quality educational resources has become an effective way to promote educational equity. The traditional educational resource sharing platforms using centralized storage architecture have security issues. Recently, many studies use blockchain to achieve secure sharing of educational resources. However, the existing blockchain‐based educational resource sharing schemes only use blockchain as a storage tool, and have issues such as low sharing efficiency, without considering copyright security, and lack of a trusted sharing environment, which prevents the large‐scale sharing of educational resources. In response, we propose ERSChain, a novel blockchain‐based educational resources sharing solution. First, we put forward a hybrid storage method that keeps the hash value of resource in the blockchain and stores the encrypted resource in the off‐chain, which can alleviate the storage and computing pressure brought by massive educational resources while ensuring the integrity of resources. Second, we construct an efficient revocable ciphertext‐policy attribute‐based encryption algorithm to implement flexible access control and an outsourced decryption algorithm to achieve greater efficiency. Obtaining access to educational resources is possible when user's attributes meet the access policy and the user's identity does not exist in the revocation list. Third, we put forward a credit mechanism to adjust the user's credibility and a credit‐based consensus mechanism to maintain the trusted sharing environment. Finally, security analysis and plentiful of experiments demonstrate that our proposed ERSChain achieves security assurance, has better applicability than similar works, and enables large‐scale sharing of educational resources.
Grouping groupers in the Mediterranean: Ecological baselines revealed by ancient proteins
Authors: Winter Rachel M. , de Kock Willemien , Mackie Meaghan , Ramsøe Max , Desiderà Elena , Collins Matthew , Guidetti Paolo , Presslee Samantha , Alegre Marta Munoz , Oueslati Tarek , Muniz Arturo Morales , Michailidis Dimitris , van den Hurk Youri , Taurozzi Alberto J. , Çakirlar Canan 
Published: October 2023

AbstractMarine historical ecology provides a means to establish baselines to inform current fisheries management. Groupers (Epinephelidae) are key species for fisheries in the Mediterranean, which have been heavily overfished. Species abundance and distribution prior to the 20th century in the Mediterranean remains poorly known. To reconstruct the past biogeography of Mediterranean groupers, we investigated whether Zooarchaeology by Mass Spectrometry (ZooMS) can be used for identifying intra‐genus grouper bones to species level. We discovered 22 novel, species‐specific ZooMS biomarkers for groupers. Applying these biomarkers to Kinet Höyük, a Mediterranean archaeological site, demonstrated 4000 years of regional Epinephelus aeneus dominance and resiliency through millennia of fishing pressures, habitat degradation and climatic changes. Combining ZooMS identifications with catch size reconstructions revealed the Epinephelus aeneus capacity for growing 30 cm larger than hitherto documented, revising the maximum Total Length from 120 to 150 cm. Our results provide ecological baselines for a key Mediterranean fishery which could be leveraged to define and assess conservation targets.
DNAbarcoding of reef‐associated fishes of Saint Martin's Island, Northern Bay of Bengal, Bangladesh
Authors: Habib Kazi Ahsan , Islam Md. Jayedul , Sakib Md. Nazmus , Brishti Parsha Shanjana , Neogi Amit Kumer 
Published: October 2023

AbstractThis study employs the DNA barcoding approach to make a molecular taxonomic catalog of reef fishes of Saint Martin's Island (SMI), an ecologically critical area (ECA), and Marine Protected Area (MPA) in Bangladesh. DNA barcoding, along with morphological analysis, confirmed 84 reef‐associated fish species in SMI belonging to 16 orders, 39 families, and 67 genera. A total of 184 sequences were obtained in this study where 151 sequences (534–604 bp) of 81 species were identified from the COI barcode gene and 33 sequences (609 bp) of 19 species from the 16S rRNA gene region which were submitted to the GenBank and Barcode of Life Data System (BOLD). Among these sequences, 70 sequences of the COI gene and 16 sequences of 16S rRNA gene region from 41 species were submitted for the first time into the GenBank from Bangladesh. For molecular characterization analysis, another 37 sequences of 15 reef fish species of SMI were added from previous studies, making a total of 221 DNA sequences which comprised 179 sequences of 96 species for the COI gene and 42 sequences of 26 species for the 16S rRNA gene region. The COI sequences contain 145 haplotypes with 337 polymorphic sites, and the mean genetic distances within species, genera, and families were calculated as 0.34%, 12.26%, and 19.03%, respectively. On the contrary, 16S rRNA sequences comprised 31 haplotypes with 241 polymorphic sites, and the mean genetic divergences within species, genera, and families were 0.94%, 4.72%, and 12.43%, respectively. This study is a significant contribution to the marine biodiversity of Bangladesh which would facilitate the assessment of species diversity for strategizing management action. It is also an important input to the DNA barcode library of reef fishes of the northern Bay of Bengal.
Habits and attitudes toward writing affect the publication output of environmental biology trainees
Authors: Alshwairikh Yara A. , Fanton Ana Clara , Prats Kyra A. , Burak Mary K. , Duguid Marlyse C. , Rowland Freya E. 
Published: October 2023

AbstractPublications are the mainstay of academic success, yet scientific writing requires consistent feedback and practice to build and maintain skills. In this study, we surveyed 342 environmental biology trainees (i.e., graduate students and postdoctoral scholars) about their writing habits. Our objective was to explore whether trainee writing habits align with suggestions from scientific writing guide books and articles, and how individual habits and attitudes may impact writing output. We found that the majority of respondents (>65%) felt negatively about writing and publishing, and few adhered to established advice such as scheduling writing time, setting attainable goals, or joining a writing accountability group. Our results show that trainees who dedicated more hours to writing each week and individually tracked their writing progress had more first‐author publications. In particular, graduate students who regularly scheduled writing time during the week and participated in writing groups also had more first‐author publications. Conversely, trainees who felt negatively about writing, wrote mainly before deadlines, and relied on “check‐ins” with advisors or writing groups to monitor writing progress had fewer first‐author publications. We describe ways that individuals, advisors, and institutions could improve trainee writing habits and assist them in developing more positive attitudes toward writing to ultimately help trainees achieve their writing goals.
Subnanomolar electrochemical sensing of mangiferin using a polycationic organohalloysite as electrode modifier
Authors: Melataguia Tchieno Francis Merlin , Dmitrieva Evgenia , Pengou Martin 
Published: October 2023

AbstractA polycationic organohalloysite (H‐polyQ22) prepared by the sequential grafting of methylamine and 1,4‐butanediol diglycidyl ether in the interlayer space of (3‐aminopropyl)trimethoxysilane grafted halloysite is herein employed as a carbon paste electrode (CPE) modifier for the electrochemical determination of mangiferin, a bioactive molecule. When H‐polyQ22 was used as CPE modifier, the cyclic voltammetric response of mangiferin increased by ca. 8‐fold. This electrochemical response enhancement was shown to be the result of the great preconcentration capacity of H‐polyQ22. Since the H‐polyQ22 modified CPE proved to be a good signal enhancer, a new methodology for the sensitive determination of mangiferin was developed using square wave voltammetry. Under optimised conditions, a linear correlation between peak current and mangiferin concentration was obtained in the range from 0 to 2775.67 nM. A detection limit of 5.47×10−10 M was obtained based on a signal to noise ratio of 3, with a sensitivity of 193.58 μA/μM. The ability of some possible interferents such as human serum albumin, L‐cystine, ascorbic acid, glucose, dopamine and phenol to perturb the electrochemical signal of mangiferin in real sample analysis was alsoinvestigated.
Effect of water on the damage and energy dissipation feature of coal under uniaxial cyclic loading–unloading condition
Authors: Song Honghua , Zhao Yixin , Wu Yang , Li Xuehao , Gong Zhixin , Sun Zhuang , Jiang Yaodong , Guo Zihan 
Published: October 2023

AbstractTo gain insight into the reduction mechanism of water on the dynamic destabilization failure character of coal under mining disturbance conditions, the effect of water on the damage and energy dissipation feature of coal was investigated via cyclic uniaxial compressive loading–unloading test, acoustic emission (AE) monitoring technology, and theoretical analysis. It manifests that the softening effect of water on the mechanical properties of coal is still remarkable, lower uniaxial compressive strength and elastic modulus, while greater axial strain and higher Poisson's ratio are observed under the cyclic loading–unloading condition. Water‐saturated specimens dissipate more energy during the cyclic loading–unloading process, which reduces the proportion of input energy accumulated in the coal mass, thus lowering the burst proneness of coal. A greater amount of damage generates in air‐dried specimens than that in water‐saturated specimens at the first cyclic loading–unloading cycle, while lower damage increments are observed in the following cycles. This may be the reason for the minimal energy dissipation of air‐dried specimens in the following cycles. The elastic modulus behaves logarithmically versus the increasing cyclic loading–unloading cycle counts. The energy dissipated due to the damage evolution and plastic deformation of coal specimens positively correlates with the energy released by AE activities, the AE energy in air‐dried specimens has a greater concentration around the peak axial stress and a stronger correlation with the dissipated energy. The cumulative AE energy and energy dissipation density are linearly correlated during the cyclic loading–unloading process, which indicates a possibility in estimating the damage evolution and the dynamic failure risk of coal via cumulative AE energy, under the cyclic loading–unloading condition.