bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS SALURAN DAN MARGIN TATA NIAGA BAWANG MERAH (Studi Kasus di Kelompok Tani Sari Tani II Desa Gebang Kecamatan Gebang Kabupaten Cirebon)
Authors: Sugiharto Joko , Sungkawa Iman , Budirokhman Dodi 
Published: February 2024

Penelitian ini bertujuan untuk mengetahui : (1) Saluran tataniaga bawang merah, (2) Besarnya marjin tataniaga pada masing-masing lembaga tataniaga bawang merah di bawang merah, (3) Saluran tataniaga mana yang lebih menguntungkan untuk para petani bawang merah, dan (4) Besarnya bagian harga yang diterima petani bawang merah (farmerâ€™s share) pada berbagai saluran tataniaga bawang merah di Desa GebangÂ Kecamatan GebangÂ Kabupaten Cirebon. Penelitian dilakukan Desa GebangÂ Kecamatan GebangÂ Kabupaten Cirebon pada bulan Agustus 2021. Desain penelitian yang digunakan dalam penelitian ini adalah medode kuantitatif, dengan pendekatan survey, dengan jumlah petani sampel 30 orang, pedagang pengumpul sebanyak 10 orang, pedagang besar 3 orang, pedagang perantara 7 orang, dan pedagang pengecer 8 orang. Data yang dikumpulkan adalah data primer dan data sekunder yang ada hubungannya dengan masalah penelitian. Data yang dihasilkan dianalisis secara deskriptif dan statistik. Analisis deskriptif digunakan untuk mengetahui saluran tataniaga dan fungsi tataniaga. Sedangkan analisis statistik digunakan untuk mengetahui marjin tataniaga dan besarnya bagian harga yang diterima petani. Hasil penelitian menunjukkan bahwa : (1) Terdapat dua sistem saluran tataniaga bawang merah di Desa Gebang Kecamatan GebangÂ Kabupaten Cirebon, yaitu Petaniâ€“Pedagang Pengumpulâ€“Pedagang Pengecerâ€“Konsumen dan Petaniâ€“Pedagang Pengumpulâ€“Pedagang Besar-Pedagang Pengecerâ€“Konsumen, (2) Marjin tataniaga bawang merah yang paling besar adalah pada saluran tataniaga II yakni Rp. 11.000 per kg (59,86%) dan yang terkecil pada saluran tataniaga I yakni Rp. 10.200 per kg (54,22%), (3) Saluran tataniaga I lebih menguntungkan dengan nilai keuntungan lebih besar dan saluran tataniaga II, dan (4) Famerâ€™s Share atau bagian harga yang dieterima petani bawang merah pada saluran tataniaga I sebesar 52,99% dan bagian harga yang diterima petani bawang merah saluran tataniaga II sebesar 51,11%.Â Kata Kunci : Analisis Saluran, Margin Tataniaga, Bawang Merah
Estudo sobre o uso de benzodiazepínicos em idosos
Authors: Franco Tafner Cossa Luciana , Pizzo Pereira Lívia , Cruz Magalhães Thainá , De Oliveira Silva Ingrid , Gastaldelo Victoria , Morandin Gambaroto Milan de Andrade Geórgia , Cristine Marini Danyelle 
Published: February 2024

Este artigo teve por objetivo analisar o consumo dos benzodiazepínicos que são importantes fármacos e estão entre os ansiolíticos mais vendidos no mundo, mostrar que apesar de boa adesão e baixa toxicidade ainda assim é contraindicado para idosos observar principalmente entre idosos, riscos e interações medicamentosas, dependência, suspenção, entre outros, Dados nos mostram que seu alto consumo está relacionado ao aumento de transtornos psicológicos. A população idosa apresenta maior alterações na farmacodinâmica e farmacocinética. A pesquisa através de questionário trouxe dados para maior entendimento, interações medicamentosas, riscos e dificuldade no desmamePara esta pesquisa foram entrevistadas através de questionário 82 pessoas com 18 perguntas, destes em questionário 40 pessoas idosas onde 20% são homes e 80% mulheres, 45,7% não tem atividade remunerada e 54,3% possui atividade remunerada, 43,2% não fez uso de benzodiazepínico e 56,8 fez uso. Referente a qual medicamento usado, 8,6% bromazepam, 8,6% alprazolan, 17,1% outros, 28,6% clonazepan e 37,1 diazepan. A respeito de tempo de tratamento 8,6% menos de 8 semanas, 25,7% mais de 5 anos, 28,6%mais de 1 ano, 37,1% toma só quando necessário. Referente a pergunta quanto a indicação, 5,7% amigos e 94,3% médicos. Para a pergunta sobre qual finalidade toma, 5,7% nervosismo, 8,6% outros, 40% insônia e 42,9% ansiedade. Se faz uso com outros medicamentos, 38,2% somente este e 58,8% entre 2 a 5 medicamentos. Dos entrevistados, 11,4% tentou parar de tomar algumas vezes, 17,1% tentou e não conseguiu parar, 25,7% parou na primeira tentativa e 45,7% nunca tentou parar e 45,7% dos entrevistados toma de forma regular. Em conclusão, na pesquisa foi observado a dificuldade para o desmame, o risco de interação medicamentosa, em sua maioria são indicações médicas, chamando atenção para que se haja um protocolo adequado para uso.
Palavras-chave: Benzodiazepínicos, idosos e interações medicamentosas.
The New Apartheid
Authors: Lepuru Masilo 
Published: February 2024

The fundamental distinction between a Civil Rights movement such as the African National Congress and a liberation movement like Poqo lies in the status of white settlers and Apartheid. The mythologisation of Apartheid by promoting it to the main problem in liberation politics and history in conqueror South Africa is the persistent intellectual obsession of the Congress Tradition. A trenchant contestation and rejection of Apartheid as the fundamental antagonism in the history of the struggle for national liberation is the defining trait of a liberation movement and liberation intellectual production.Having written a book entitled Democracy & Delusion: 10 Myths (2019), in which he debunks what he considers to be myths about the so-called post-Apartheid South Africa, Sizwe is back again only this time he is reinventing two myths.In the book under review, entitled The New Apartheid (2021), Sizwe promotes the delusion and first myth of Apartheid as the problem and the second myth of the ANC as a liberation movement. This review is about these two myths.
Пароксизмална нощна хемоглобинурия – диагноза, клинична картина и нови терапевтични възможности
Authors: Белева Елина 
Published: February 2024

Пароксизмалната нощна хемоглобинурия (ПНХ) е хронично мултисистемно, прогресивно и животозастрашаващо заболяване, което се характеризира с вътресъдова хемолиза, тромботични инциденти, тежки инфекции и костно-мозъчна недостатъчност. ПНХ е рядко заболяване с очаквана болестност по данни за Orphanet 2/100 000.
Парадигмата в лечението на ПНХ се променя с въвеждането на комплементна блокада посредством анти-С5 антитела и инхибитори на проксимални компоненти на комплемента. Блокадата на комплемента постига значима редукция на тромботичните усложнения, стабилно ниво на хемоглобин, контрол на хемолизата и подобряване качеството на живот при пациентите с ПНХ. Лечението с комплементни инхибитори подобрява свързаните с ПНХ органни усложнения като бъбречна недостатъчност и пулмонална хипертония.
В настоящия обзор са обобщени и представени актуални насоки за лечение на ПНХ, публикувани от международни и европейски национални дружества по хематология, както и са сравнени индикации за започване и преустановяване на терапия с анти-С5 инхибитори според ПНХ работни групи в редица европейски държави.
Изключително рядък случай на множествени карциноми
Authors: Желязков Константин , Андонов Владимир 
Published: February 2024

Гастроезофагеалната рефлуксна болест (ГЕРБ) се явява едно от най-честите заболявания не само в гастроентерологията, но и в медицината като цяло. Макар да протича с нисък морталитет, клиничните симптоми значително нарушават качеството на живот на засегнатите пациенти и ги откъсват от нормалната им среда. При една част от болните възникват хранопроводни и извънхранопроводни усложнения, като най-характерното усложнение е развитието на Баретов хранопровод (БХ). Пациентите с това усложнение имат над 30 пъти по-висок риск от развитие на аденокарцином на хранопровода. При една немалка част от тях се наблюдава и паралелно сформиране на редица други малигнени заболявания, които трайно инвалидизират пациентите и намаляват продължителността им на живот.
Представяме случай на 71-годишен пациент с хистологично верифицирани карцином на простатната жлеза, умеренодиференциран плоскоклетъчен карцином на бял дроб с метастази в супраклавикуларните и медиастинални лимфни възли, базоцелуларен карцином на ляво бедро, двустранни аденоми на надбъбречните жлези на фона на 5-кратни кръвоизливи от стомашна язва, ерозивен гастрит и изразена ГЕРБ, усложнена с преканцерозата на хранопровода и стомаха – БХ.
An Update on National Consensus Practice Guidelines for the Treatment of Hepatitis C & Literature Review in Epidemiology of Hepatitis C in Pakistan - 2022
Authors: Syed Sibt ul Hasnain , Umar Muhammad , Khaar Hamama tul Bushra , Akhter Tayyab Saeed , Hussain Tassawar , Salamat Amjad , Ahmad Syed Irfan , Asghar Rai Muhammad , Khurram Muhammad , Khan Anwar A. , Fazl-e-Hadi  , Mohsin Aftab , Waseem-Ud-Din  , Qureshi Saleem , Bhutta Sohail Iqbal , Khan Javeria Zahid , Ahmad Sadia , Naseer Aqsa , Abbas Anum , Noreen Misbah , Aslam Faiza , Minhas Zahid Mahmood , Naqvi Asif Abbas , Shoaib Atifa , Ambreen Saima , Nisar Gul , Khan Mohammad Mujeeb , Khursheed Talal , Osama Mohammad 
Published: February 2024

Hepatitis C is a global health problem affecting around 58 million people worldwide and killing almost 0.29 million in on one year [1]. The world has united to fight against this lethal disease in 2016 with a moto to eliminate hepatitis by 2030. To achieve this goal WHO’s World Health Assembly has set some targets and individual countries have developed their own strategies to achieve those targets [2]. Pakistan has the 2nd highest prevalence of hepatitis C in the world with 5.8% viremia positive patients [3]. Pakistan is amongst the few countries that have been assisted by the Center for Disease Control and Prevention(CDC) to prevent and control Hepatitis[4].
With the availability of Direct Acting Antivirals(DAAs), the whole paradigm of treatment of hepatitis C has changed not only globally but also in Pakistan. However, the patients in Pakistan are unable to gain access to the latest DAAs at the pace, as they are available globally. International guidelines are being updated on regular basis as per global evidence, recommending such combinations which are not readily available to many parts of the world. Hence there is a dire need to develop national guidelines, keeping in consideration the efficacy of the drugs as well as their availability, in the broader canvas of achieving the targets of eliminating Hepatitis set by WHO.
In this context, our consensus guidelines are an effort to fill the gap created because of upgraded scientific evidence and possible combinations available in our part of the world. Furthermore, quite some good research and evidence has also been shared in the literature from Pakistan during last five years (2016-2021). Hence a literature review has also been carried out to update our own epidemiologic data, risk factors and treatment responses to Hepatitis C in Pakistan.
Contribution of the real estate sector in the city of esmeraldas: a sustainable and sustainable vision
Authors: Egas-Posligua Laura Marcela , Palacios-Cedeño Nohemí Monserrate 
Published: February 2024

The study analyzes the factors that contribute to the sustainable and sustainable development of the real estate sector in the city of Esmeraldas, in terms of employment generation, investment promotion, sustainable urban development and tax revenue generation. Therefore, the research focused onto analyze the contribution of the real estate sector in the city of Esmeraldas towards a sustainable and sustainable vision . The study was based on the type of documentary research, which allowed to deepen the most relevant findings on the contribution of the real estate sector to boost the local economy. Among its derivations, it is highlighted that the real estate sector in Esmeraldas is channeled in the construction of properties oriented towards the sale and rental of real estate, experiencing significant changes in the period 2015-2021, with a gradual increase in the execution of construction projects supported by public and private investment, allowing the local economic reactivation and contributing to sustainable development, valuing and promoting the competences of the local economy.
Introducing a Supportive Framework to Address Students’ Misconceptions and Difficulties in the Learning Mathematical Proof Techniques: A Case of Debark University in Ethiopia
Authors: Belay Aschale Moges , Machaba France , Makgakga Tšhegofatšo Phuti 
Published: February 2024

This research article is about "Introducing a Supportive Framework to Address Students' Misconceptions and Difficulties in Learning Mathematical proof techniques (MPT): A Case of Debark University”. This study aims to develop, introduce, and implement a supportive framework to overcome students’ misconceptions and difficulties in MPT. The framework, named IR2CP2CE, was developed, introduced, and implemented at Debark University in Ethiopia using various data-gathering instruments such as questionnaires, interviews, classroom observations, and document analysis from students and instructors. The study collected data over four months, including the implementation of a supportive framework using mixed, quasi-experimental, and pragmatism research approaches, designs, and paradigms respectively. The internal reliability of the data-gathering instruments was interpreted using Cronbach’s coefficient, Spearman-Brown, Spearman correlations, Kuder-Richardson 20 and 21, and difficulty and discrimination indices. The results showed that the implementation of the supportive framework led to significant improvements in students’ academic performance in MPT, regardless of factors such as gender, academic year category, and preliminary knowledge and proving skills. This study recommends additional imperatives for practice and future research.
An Educational Intervention Based on Health Belief Model for Improving Breast Self – Examination behavior Among Rural Women in Hai Duong, Vietnam: A random Control Trial
Authors: Nguyen Hang Thi , Thanh Tung Le , Van Viet Tran , Thu Huong Truong Thi , Van Hung Pham 
Published: February 2024

Purpose: The goal of this study was to assess the effect of an educational intervention on breast self-examination (BES) behavior based on a Health Belief Model among Vietnamese women living in some rural areas of Hai Duong province.
Methodology: A random control trial study was conducted in two rural communes in Hai Duong province, Vietnam. Among 204 women participating in the study, they were allocated randomly into an experimental group (n=99) and a control group (n=105). An educational intervention was developed based on the Health Belief Model. An improving breast self-examination behavior of participants was assessed through doing BSE or not, frequency of BSE, and how to perform BSE.
Findings: At baseline, there were no differences between the two groups about general characteristics and breast self-examination percentage. After 3 months of the intervention, breast self-examination behavior including the rate of patients doing BSE, frequency of BSE, and performing BSE with good results in the intervention group were higher than those of the control group. (p<0.05).
Unique Contribution to Theory, Policy and Practice: Research results indicated that an educational program based on the Health Belief Model can improve breast self-examination behavior among rural women. Therefore, the educational intervention program based on the Health Belief Model should be expanded to women living in other rural areas of Vietnam.
Medicalização e violação de direitos: uma cartografia sobre as diferenças nas infâncias
Authors: Vieira de Souza Simone , Viégas Lygia de Sousa 
Published: February 2024

Nesse artigo, partilhamos reflexões suscitadas a partir do exercício prévio de cartografia de experiências teórico-metodológicas que compreendessem a criança como um sujeito de direitos, e, na contramão disso, do mapeamento da produção de um território que tem violado direitos por meio de práticas medicalizantes da infância. Para isso, realizamos um estudo cartográfico – orientado pela Psicologia Escolar e Educacional em uma perspectiva crítica –, com base no levantamento de bibliografia acadêmica publicadas na Scientific Electronic Library Online – SciELO Brasil, com os descritores medicalização e educação, no período compreendido entre 2010 e 2020; e a leitura de três dossiês sobre a medicalização no Brasil, publicados nas revistas Entreideias, Nuances e Práxis Educacional. Por meio de leituras e registros, longe de tecer um estado da arte, nos limitamos a construir pistas para compor linhas de conexão e inteligibilidade do fenômeno estudado. Nesse processo, como pistas cartográficas, delineamos: Pista 1: A medicalização nega as desigualdades sociais; Pista 2: A medicalização viola direitos e restringe a liberdade da criança; Pista 3: A medicalização produz sofrimento e exclusão da criança; e Pista 4: Em defesa da vida e por uma racionalidade não medicalizante. Esperamos, com a análise proposta, contribuir para a compreensão crítica da medicalização da educação, somando com as lutas pela garantia dos direitos das infâncias.
PALAVRAS-CHAVE: Medicalização; infância; direitos humanos.
Implementation of Non Academic Learning for Students With Intellectual Disabilities
Authors: Fadilah Nurul , Sabillah Zita Andini , Nurhamidah Azkiya , Fitriyani Fitriyani 
Published: February 2024

The primary goal of the learning process at SLBN Kabupaten Bekasi is to help develop the skills of students with special needs so that they do not feel different from their normal peers and can be accepted in society. This involves providing learning opportunities for children with Tunagrahita. The research conducted is a qualitative descriptive study aiming to present data in accordance with the realities observed in the field. The study involves the Vice Principal of SLBN Kabupaten Bekasi, skillful teachers, or Counseling Guidance teachers, and a mildly intellectually disabled Tunagrahita student. Data collection utilizes observation, interviews, and documentation. Observations at SLBN Kabupaten Bekasi indicate that the school implements a learning system for all students without discrimination. The guidance or teaching approach applied takes into consideration the characteristics and challenges faced by students, reflecting an effort to provide services tailored to their individual needs.
Elexacaftor-Tezacaftor-Ivacaftor and Ivacaftor (Trikafta)
Authors: CADTH  
Published: February 2024

CADTH reimbursement reviews are comprehensive assessments of the clinical effectiveness and cost-effectiveness, as well as patient and clinician perspectives, of a drug or drug class.
The assessments inform non-binding recommendations that help guide the reimbursement decisions of Canada's federal, provincial, and territorial governments, with the exception of Quebec.
This review assesses elexacaftor-tezacaftor-ivacaftor and ivacaftor (Trikafta):

Elexacaftor 100 mg–tezacaftor 50 mg–ivacaftor 75 mg (granules) and ivacaftor 75 mg (granules), oral
Elexacaftor 80 mg–tezacaftor 40 mg–ivacaftor 60 mg (granules) and ivacaftor 59.5 mg (granules), oral

Patients aged 6 years and older:

Elexacaftor 50 mg–tezacaftor 25 mg–ivacaftor 37.5 mg (combination tablet) and ivacaftor 75 mg (tablet), oral
Elexacaftor 100 mg–tezacaftor 50 mg–ivacaftor 75 mg (combination tablet) and ivacaftor 150 mg (tablet), oral.

Indication: For the treatment of cystic fibrosis (CF) in patients aged 2 years and older who have at least 1 F508del mutation in the cystic fibrosis transmembrane conductance regulator (CFTR) gene.
Analisis Lanskap Linguistik Iklan Kota Harapan Indah Serta Rekomendasinya Sebagai Brosur Teks Iklan Kelas VIII
Authors: Winarti Asih , Syafroni Roni Nugraha , Maspuroh Uah 
Published: February 2024

Penelitian ini mengungkap penggunaan bahasa pada lanskap linguistik berupa iklan di Kota Harapan Indah. Tujuan penelitian ini untuk mengetahui kode bahasa, variasi bahasa, konfigurasi posisi penempatan bahasa, dan fungsi lanskap linguistik yang digunakan. Penelitian ini menggunakan metode deskriptif kualitatif. Teknik pengumpulan data digunakan dengan teknik observasi dan teknik fotografi. Teknik analisis data yang digunakan model Miles dan Hubertman yang dimulai dar pengumpulan data, reduksi data, penyajian data, dan kesimpulan. Hasil penelitian menunjukkan terdapat terdapat empat bahasa yang digunakan dalam lanskap linguistik iklan di Kota Harapan Indah, yaitu bahasa Indonesia, bahasa Inggris, bahasa Jepang dan bahasa Arab. Kode bahasa yang digunakan, yaitu bilingual, dan multilingual. Variasi bahasa yang digunakan meliputi bahasa Indonesia, bahasa Inggris, bahasa Indonesia-Inggris, bahasa Arab-Indonesia, bahasa Indonesia-Inggris-Jepang. Adapun konfigurasi posisi penempatan bahasa yang digunakan berupa konfigurasi vertikal dan horizontal. Fungsi lanskap yang digunakan hanya fungsi sosial dan identitas.
Implementasi Program Penanggulangan TB Paru di Puskesmas Besulutu Kecamatan Besulutu Kabupaten Konawe
Authors: Sasmita Mega , Zainuddin Asnia , Yuniar Nani 
Published: February 2024

Tuberkulosis adalah suatu penyakit menular langsung yang disebabkan oleh kuman Mycobacterium tuberculosis, penyakit ini sebagian besar menyerang pada bagian Paru. Tuberkulosis saat ini menjadi perhatian global dan perlu diwaspadai, karena ialah salah satu dari penyebabnya terjadinya kematian yang ada di dunia ini Penelitian dilakukan untuk mengetahui gambaran implementasi program penanggulangan TB paru di Puskesmas Besulutu Kecamatan Besulutu Kabupaten Konawe. Penelitian ini dilakukan di Puskesmas Besulutu Kecamatan Besulutu Kabupaten Konawe. Alasan pemilihan lokasi karena berdasarkan Profil Kesehatan Kabupaten Konawe diketahui bahwa angka kesembuhan TB Paru yang telah dicapai Puskesmas Besulutu masih tergolong rendah yaitu sebesar 65%, sedangkan target angka kesembuhan secara nasional sebesar 85%. Penelitian dilakukan pada bulan November tahun 2023 sampai selesai. Hasil penelitan menunjukkan bahwa Program penanggulangan TB paru dengan 5 komponen strategi DOTS di Puskesmas Besulutu belum maksimal, dalam penatalaksanaannya masih belum sesuai dengan strategi DOTS (Directly Observed Treatmen, Short-course). Angka kesembuhan kasus TB Paru sangat minim. Hal ini disebabkan karena penemuan kasus yang dilakukan selama ini hanya menunggu penderita datang ke puskesmas, bukan dengan melakukan penemuan kasus secara aktif ke masyarakat.
The Determinant of Demand and Supply to Increase Tourism Visit Sustainably by Using Principal Component Regression Analysis
Authors: Murniati  , Maski Ghozali , Noor Iswan , Ekawaty Marlina 
Published: February 2024

Objectives: This research is entitled Determinants of Demand and Supply to Increase Visits in a Sustainable Way Using Principal Component Regression Analysis. Tourism is important where Malang Regency has attractive natural resource potential, and a very strategic geographical location surrounding two cities, namely Malang City and Batu City, surrounded by western and southern routes, and has an interesting culture so that tourism development is different. from the other. Visits of tourists, especially foreign tourists who have been unstable in the last two years have decreased. Limited use of technology in management and development.

Method: Research data collection technique with a quantitative descriptive method with the Principal Component Regression Analysis tool. Meanwhile, supply tourism has a very high appeal, such as an attractive tourist attraction.

Results: Based on the aspect of accessibility, they tend to have important infrastructure and access but have not been managed optimally, besides that there are still many traditional promotions and management that have caused tourist visits to be not optimal and the quality of human resources still needs to be improved.

Conclusions: Based on the research results, it is known that in terms of tourism supply, the biggest factors influencing tourist attractions are attractions and amenities. Meanwhile, from the tourism demand side, these are preference and motivation factors which are influenced by changes in consumer behavior. The results of this study are expected to be input in developing tourism in Malang Regency which can increase tourist visits thereby increasing economic growth and sustainable community welfare.