bluuebunny/crossref_metadata_2025_split huggingface dataset:
Studies on solubility measurement of codeine phosphate (pain reliever drug) in supercritical carbon dioxide and modeling
Authors: Sodeifian Gholamhossein , Garlapati Chandrasekhar , Arbab Nooshabadi Maryam , Razmimanesh Fariba , Roshanghias Armin 
Published: November 2023

AbstractIn this study, the solubilities of codeine phosphate, a widely used pain reliever, in supercritical carbon dioxide (SC-CO2) were measured under various pressures and temperature conditions. The lowest determined mole fraction of codeine phosphate in SC-CO2 was 1.297 × 10−5 at 308 K and 12 MPa, while the highest was 6.502 × 10−5 at 338 K and 27 MPa. These measured solubilities were then modeled using the equation of state model, specifically the Peng-Robinson model. A selection of density models, including the Chrastil model, Mendez-Santiago and Teja model, Bartle et al. model, Sodeifian et al. model, and Reddy-Garlapati model, were also employed. Additionally, three forms of solid–liquid equilibrium models, commonly called expanded liquid models (ELMs), were used. The average solvation enthalpy associated with the solubility of codeine phosphate in SC-CO2 was calculated to be − 16.97 kJ/mol. The three forms of the ELMs provided a satisfactory correlation to the solubility data, with the corresponding average absolute relative deviation percent (AARD%) under 12.63%. The most accurate ELM model recorded AARD% and AICc values of 8.89% and − 589.79, respectively.
Deep asymmetric extraction and aggregation for infrared small target detection
Authors: Lin Zhongwu , Ma Yuhao , Ming Ruixing , Yao Guohui , Lei Zhuo , Zhou Qinghui , Huang Min 
Published: November 2023

AbstractInfrared small target detection is widely applied in military and civilian fields. Due to the small size of infrared targets, textural detail is missing. Common target detection methods extract semantic feature by narrowing down the feature map several times, which may lead to the small targets lost in deep layers and are not effective for infrared small target detection. To solve this problem, we propose a novel network called deep asymmetric extraction and aggregation. The network mainly consists of two processes - the vertical feature extraction and the horizontal feature aggregation, both of which are enhanced by an asymmetric attention mechanism. In the vertical process, the use of asymmetric attention mechanism combined with the reduction of down-sampling makes the small target better retained in the deep layers. Then through the horizontal process, shallow spatial feature and deep semantic feature are aggregated to further highlight the small targets while suppressing background noise. Experiments on the public datasets NUAA-SISRT, NUDT-SISRT and MDvsFA-cGan show that our proposed network outperforms the state-of-the-art methods in terms of detection accuracy and parameter efficiency.
Molecular epidemiology, clinical analysis, and genetic characterization of Zika virus infections in Thailand (2020–2023)
Authors: Khongwichit Sarawut , Chuchaona Watchaporn , Vongpunsawad Sompong , Poovorawan Yong 
Published: November 2023

AbstractTo investigate the clinical and molecular characteristics and evolution of the Zika virus (ZIKV) in Thailand from March 2020 to March 2023. In all, 751 serum samples from hospitalized patients in Bangkok and the surrounding areas were screened for ZIKV using real-time RT-PCR. Demographic data and clinical variables were evaluated. Phylogenetic and molecular clock analysis determined the genetic relationships among the ZIKV strains, emergence timing, and their molecular characteristics. Among the 90 confirmed ZIKV cases, there were no significant differences in infection prevalence when comparing age groups and sexes. Rash was strongly associated with ZIKV infection. Our ZIKV Thai isolates were categorized into two distinct clades: one was related to strains from Myanmar, Vietnam, Oceania, and various countries in the Americas, and the other was closely related to previously circulating strains in Thailand, one of which shared a close relation to a neurovirulent ZIKV strain from Cambodia. Moreover, ZIKV Thai strains could be further classified into multiple sub-clades, each exhibiting specific mutations suggesting the genetic diversity among the circulating strains of ZIKV in Thailand. Understanding ZIKV epidemiology and genetic diversity is crucial for tracking the virus's evolution and adapting prevention and control strategies.
Clinical Feeding and Swallowing Evaluation for the School-Based Speech-Language Pathologist
Authors: D'Angelo Elisabeth C. 
Published: November 2023

Purpose:
From preschool through high school, eating is part of the school day. Children with feeding and/or swallowing issues are now in our neighborhood schools, our responsibility in our care, and require adequate nutrition and hydration to participate in school and access the curriculum. The whole child is in school, including all of their medical, behavioral, social, and educational needs. This clinical focus article describes a holistic process of evaluating swallowing and feeding in the school setting for the school speech-language pathologist (SLP) leading the team supporting the child.

Method:
This clinical focus article explores the evaluation process in the educational setting for the school SLP in identification of pediatric feeding disorders (PFDs), which can involve dysphagia. Detailed descriptions of the related U.S. educational law, PFD, assessment processes for the multiple systems relating to eating, and collaboration with an interdisciplinary team are highlighted. Using the four overlapping domains of PFD (medical, psychosocial, feeding skill-based systems and associated nutritional aspects), medical and background history gathering; integration with instrumental results; and the need to consider the complex interaction of developmental, physical, cognitive, social, behavioral, family, and cultural aspects in the evaluation are detailed.

Conclusions:
School-age children require safe and adequate nutrition and hydration for learning and social participation. The SLP has a lead role in the school team in evaluating swallowing and feeding, and developing a plan for team implementation. A holistic school-based SLP clinical evaluation process is described.
Pedestrian intention estimation and trajectory prediction based on data and knowledge‐driven method
Authors: Zhou Jincao , Bai Xin , Fu Weiping , Ning Benyu , Li Rui 
Published: November 2023

AbstractWith the development of deep learning technology, the problem of data‐driven trajectory prediction and intention recognition has been widely studied. However, the pedestrian trajectory prediction and intention recognition methods based solely on data‐driven have weak data description ability and black‐box characteristics, which cannot reason about pedestrian crossing intention and predict pedestrian crossing trajectory as humans do. To address the above problems, the authors proposed a data and knowledge‐driven pedestrian intention estimation and trajectory prediction method by imitating human cognitive mechanisms. In the pedestrian intention inference process, the authors adopted the knowledge‐driven method. As a first step, the authors built a knowledge graph of pedestrian crossing scenes, and then paired it with a Bayesian network to estimate pedestrian crossing intentions. In the pedestrian trajectory prediction process, the authors used a data‐driven approach, combining pedestrian crossing trajectory features and knowledge‐based pedestrian intentions. Experiments show that all evaluation metrics of pedestrian trajectory prediction were improved after adding pedestrian intentions obtained by knowledge‐driven.
Securing smart home against sinkhole attack using weight‐based IDS placement strategy
Authors: Islam Md. Shafiqul , Tasnim Muntaha , Kabir Upama , Jahan Mosarrat 
Published: November 2023

AbstractExtensive use of the Internet of Things (IoT) in smart homes makes users' lives easy and comfortable. Yet, these resource‐constrained devices are prone to manifold security attacks. The sinkhole attack is one of the most destructive attacks that disrupt smart home operations, causing user dissatisfaction. Existing intrusion detection systems (IDS) cannot handle sinkhole attacks competently as they (i) do not consider the node capacity for being an IDS agent, leading to a low attack detection ratio, (ii) do not examine the sinkhole node's role when mitigating attacks, causing remaining network disconnection with the root node and (iii) do not consider replacing energy‐exhausted IDS nodes, causing connectivity loss of partial network with the root. This paper addresses these shortcomings and adequately presents a mechanism to handle sinkhole attacks. A formulation for assigning weights to network nodes based on their resources is proposed here. An IDS placement strategy is introduced to place IDS agents on particular resourceful nodes that extend network lifetime and enhance attack detection capability. We present a novel attack detection and mitigation strategy by ensuring network connectivity. The proposed mechanism achieves 95% attack detection accuracy and reduces false negative rates by 25% and energy consumption reasonably compared to the state‐of‐the‐art.
Enjeux historiques et philosophiques de l’expérimentation animale
Authors: Chapouthier Georges 
Published: November 2023

Les ébauches de l’expérimentation animale peuvent être trouvées dans l’Antiquité, mais sa pratique moderne s’amorce à partir de la Renaissance. C’est Claude Bernard qui en analyse au XIXesiècle les bases, fondées sur le concept philosophique cartésien de l’animal-machine. Mais le développement même de la biologie bernardienne a révélé que les animaux, notamment les animaux dits « sentients », disposent de processus de sensibilité et de conscience proches de ceux des êtres humains. D’où un souci moral qui se glisse, de nos jours, dans l’expérimentation animale et qui conduit à diverses améliorations du traitement des animaux d’expérience.
L’encéphalose hépatique
Authors: Jolivet Franck 
Published: November 2023

L’encéphalose hépatique est causée par une insuffisance hépatique sévère, notamment lors d’anomalies vasculaires (shunts porto-systémiques congénitaux notamment ou shunts acquis).
Bien que la pathogénie de l’encéphalose hépatique ne soit pas totalement élucidée, l’hyperammoniémie joue un rôle central, en agissant principalement en tant que neurotoxine sur les astrocytes, générant un œdème cérébral. L’encéphalose hépatique est classée selon 5 grades cliniques, de l’animal asymptomatique (grade 0) à l’animal comateux (grade 4).
Le diagnostic est basé sur une association de signes cliniques, biochimiques, et une réponse rapide au traitement médical.
La prise en charge d’une encéphalose hépatique inclut un traitement de soutien immédiat, l’identification et le traitement des facteurs prédisposants, et un traitement au long terme.
Le traitement passe par l’utilisation du lactulose ou du lactitol, et une alimentation adaptée. La restriction protéique doit être évitée car elle peut aggraver l’encéphalose hépatique. Enfin l’utilisation d’une antibiothérapie ne doit pas être systématique, mais seulement réservée à des cas sévères ou ne répondant pas correctement aux premiers traitements.
Acousto-optic modulators
Authors: Darde Franck , Beeharee Ricky 
Published: November 2023

The laser invention in 1960 has led to the development of acousto-optics and its applications, mainly for deflection, modulation and signal processing.
Technical progresses in both crystal growth and high frequency piezoelectric transducers have brought valuable benefits to acousto-optic components ‘improvements and the use of these components in scientific and industrial applications.
Stillschweigen und viele Fragezeichen
Authors: Lukuc Sarah 
Published: November 2023

ZusammenfassungUm langfristig die Arbeitsbedingungen von Pflegenden in Kliniken und Langzeitpflege-einrichtungen verbessern zu können, ist die Einführung von PPR 2.0. und PeBeM notwendig. Noch gibt es aber viele offene Fragen.
Die Pflegepersonalregelung 2.0
Authors: Evers Arne 
Published: November 2023

ZusammenfassungEinigen Führungskräften ist die PPR aus den 90ern noch bekannt, für viele ist sie jedoch ein ganz neues Kapitel: Lesen Sie hier, kurz zusammengefasst, die wichtigsten Details zur PPR 2.0.
Der Weg zu einem validen Instrument
Authors: Trux Marc-Justin 
Published: November 2023

ZusammenfassungDas PeBeM ist da – nur noch nicht überall. Zumindest in Nordrhein-Westfalen konnten einige Häuser dank landesrechtlicher Anpassungen fristgerecht starten. Aktuell bedeutet die Implementierung bundesweit einen erheblichen Aufwand für das Management, langfristig erhalten die Häuser aber einen deutlichen Personalzuwachs.
Orale Störfelder und ihre Bedeutung für die interdisziplinäre Medizin
Authors: Nadj-Papp Edith 
Published: November 2023

ZusammenfassungMund und Körper sind eng miteinander vernetzt. Was historisch durch die parallele Ausbildung (Humanmedizin, Zahnmedizin) künstlich getrennt wurde, muss entsprechend der physiologischen Gegebenheiten erneut zusammenwachsen. Ein gut funktionierendes interdisziplinäres Netzwerk trägt maßgeblich zur verbesserten Patientenversorgung bei und erhöht die Patientenzufriedenheit. Störfelder und Herde sind kleine chronische Veränderungen, die als permanente Reize sowohl bestehende chronische Erkrankungen verstärken als auch Auslöser von allgemeinen Beschwerden sein können. Wenn sie lange unerkannt bleiben, schwächen sie das Immunsystem. Ziel dieses Artikels ist, auf das orale Herdgeschehen aufmerksam zu machen, geeignete diagnostische und therapeutische Möglichkeiten vorzustellen sowie das Potenzial der interdisziplinären Zusammenarbeit aufzuzeigen.
Efficient Preparation of O-Isopropylidene Derivatives of Carbohydrates Catalyzed by Sulfonated Graphene (GR-SO3H) as a Sustainable Acid Catalyst
Authors: Panchadhayee Rajib , Rabha Padmashri 
Published: November 2023

AbstractSulfonated graphene (GR-SO3H) has emerged as a mild, efficient and sustainable catalyst for the preparation of O-isopropylidene derivatives of unprotected and anomeric-protected carbohydrates with acetone and 2,2-dimethoxypropane at room temperature. This methodology not only provides excellent yields but also reduces reaction times, and it demonstrates exceptional recyclability, allowing the catalyst to be reused multiple times.
The Role of Thyroid Hormones, Vitamins, and Microelements in Female Infertility
Authors: Aghayeva Sveta , Sonmezer Murat , Şükür Yavuz Emre , Jafarzade Aytaj 
Published: November 2023

Abstract
Objective It is well known that female infertility is multifactorial. Therefore, we aimed to compare the effects of thyroid dysfunction, vitamin deficiency, and microelement deficiency in fertile and infertile patients.
Materials and Methods Between May 1st, 2017, and April 1st, 2019, we conducted a retrospective case-control study with of 380 infertile and 346 pregnant patients (who normally fertile and able to conceive spontaneously). The fertile patients were selected among those who got pregnant spontaneously without treatment, had a term birth, and did not have systemic or obstetric diseases. The levels of thyroid-stimulating hormone (TSH), triiodothyronine (T3), thyroxine (T4), anti-thyroid peroxidase (anti-TPO), vitamin D, vitamin B12, folic acid, ferritin, and zinc of both groups were compared.
Results There was no difference between patients in the infertile and pregnant groups in terms of low normal and high serum T3 and T4 levels (p = 0.938; p > 0.05) respectively, nor in terms of normal and high anti-TPO levels (p = 0.182; p > 0.05) respectively. There was no significant difference regarding patients with low, insufficient, and sufficient vitamin D levels in the infertile and pregnant groups (p = 0.160; p >0.05) respectively. The levels of folic acid, ferritin, and zinc of the infertile group were significantly lower than those of the pregnant group.
Conclusion The serum levels of folic acid, ferritin, and zinc in infertile patients presenting to our outpatient clinic were lower than those o the fertile patients.
Factors Related to Low COVID-19 Vaccination Rate in Pregnant and Postpartum Women with and without COVID-19
Authors: Beser Dilek Menekse , Hendem Derya Uyan , Oluklu Deniz , Turgut Ezgi , Hancerliogullari Necati , Ayhan Sule Goncu , Tekin Ozlem Moraloglu , Sahin Dilek 
Published: November 2023

Abstract
Objective This study focused on pregnant and postpartum women during the COVID-19 pandemic, aiming to determine the attitudes and behaviors of vaccinated and unvaccinated groups, and the vaccination behaviors in the groups with and without the disease. The reasons for refusing the vaccine were also questioned.
Methods This cross-sectional study was performed from September 2021 to October 2021. The study data were collected using a face-to-face questionnaire. The participants were pregnant women who applied to the hospital for routine antenatal care and were hospitalized, and women in the postpartum period. Additionally, pregnant and postpartum patients who were diagnosed with COVID-19 at the time of admission and were hospitalized and admitted to the intensive care unit due to this disease were also included in the study.
Results A total of 1,146 pregnant and postpartum women who completed the questionnaire were included in our study. Only 43 (3.8%) of the participants were vaccinated; 154 (13.4%) of the participants had comorbidities. The number of COVID-19-positive patients was 153. The lack of sufficient information about the safety of the COVID-19 vaccine is the most common reason for the refusal.
Conclusion Vaccine refusal can significantly delay or hinder herd immunity, resulting in higher morbidity and mortality. Considering the adverse effects of COVID-19 on pregnancy, it is essential to understand pregnant and postpartum women's perceptions toward vaccination to end the pandemic.
Sexual Function of Patients with Deep Endometriosis after Surgical Treatment: A Systematic Review
Authors: Cervantes Graziele Vidoto , Ribeiro Paulo Augusto Ayroza Galvão , Tomasi Mariana Carpenedo , Farah Daniela , Ribeiro Helizabet Salomão Abdalla Ayroza 
Published: November 2023

Abstract
Objective To review the current state of knowledge on the impact of the surgical treatment on the sexual function and dyspareunia of deep endometriosis patients.
Data Source A systematic review was conducted in accordance with the Meta-Analysis of Observational Studies in Epidemiology (MOOSE) guidelines. We conducted systematic searches in the PubMed, EMBASE, LILACS, and Web of Science databases from inception until December 2022. The eligibility criteria were studies including: preoperative and postoperative comparative analyses; patients with a diagnosis of deep endometriosis; and questionnaires to measure sexual quality of life.
Study Selection Two reviewers screened and reviewed 1,100 full-text articles to analyze sexual function after the surgical treatment for deep endometriosis. The risk of bias was assessed using the Newcastle-Ottawa scale for observational studies and the Cochrane Collaboration's tool for randomized controlled trials. The present study was registered at the International Prospective Register of Systematic Reviews (PROSPERO; registration CRD42021289742).
Data Collection General variables about the studies, the surgical technique, complementary treatments, and questionnaires were inserted in an Microsoft Excel 2010 (Microsoft Corp., Redmond, WA, United States) spreadsheet.
Synthesis of Data We included 20 studies in which the videolaparoscopy technique was used for the excision of deep infiltrating endometriosis. A meta-analysis could not be performed due to the substantial heterogeneity among the studies. Classes III and IV of the revised American Fertility Society classification were predominant and multiple surgical techniques for the treatment of endometriosis were performed. Standardized and validated questionnaires were applied to evaluate sexual function.
Conclusion Laparoscopic surgery is a complex procedure that involves multiple organs, and it has been proved to be effective in improving sexual function and dyspareunia in women with deep infiltrating endometriosis.
Effect of Lubricant Use on Cervicovaginal Cytology – What's the Evidence?
Authors: Santos Diana Magalhães dos , Matos Maria Beatriz Freire Oliveira Coelho de , Sousa Ana Raquel Borges , Fertusinhos Francisco Correia de Almeida , Pendás Rosa Maria Couceiro 
Published: November 2023

Abstract
Objective To determine if the use of lubricating gel on the speculum during the cervicovaginal cytology examination interferes with the results obtained, as well as whether it reduces reported discomfort in patients.
Data sources A systematic review was carried out according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, with a search in the Pubmed/Medline, Scielo, Cochrane Library, Embase databases of articles published between January 2011 and May 2022. The keywords used were cytology, speculum, lubricant, result, and pain.
Selection of studies The initial search resulted in 306 articles, of which were excluded three because they were duplicates, 257 after reading the title and abstract and 41 after reading the full text. Thus, five articles were selected for the study: four randomized clinical trials and one metanalysis.
Data collection The selection of articles was performed by two investigators. The 5 selected articles were read in full and submitted to a comparative analysis.
Data synthesis Screening through cervicovaginal cytology allows for early diagnosis and reduction of associated mortality, but the procedure can be associated with pain. A small amount of aqueous lubricating gel in the speculum can be used to reduce the discomfort associated with performing cervicovaginal cytology.
Conclusion The use of lubricating gel in the speculum does not seem to be associated with a change in the cytology result and reduces the discomfort associated with its insertion into the vagina.
Endometrial Progesterone and Estrogen Receptors in Relation to Hormonal Levels in Women with Unexplained Recurrent Miscarriage
Authors: Gomaa Ihab Adel , Sabry Ahmed , Allam Ihab Serag El-Din , Ashoush Sherif , Reda Ahmed 
Published: November 2023

Abstract
Objective Recurrent miscarriage has been linked to hormonal disturbance due to dysregulation of its receptors rather than to the availability of the hormone. We aimed to investigate endometrial expression of progesterone and estrogen receptors in relation to serum and endometrial hormonal levels in unexplained recurrent miscarriage.
Methods The present case control study included 20 cases with unexplained recurrent miscarriage and 20 parous women as controls. Ovulation was confirmed using an ovulation kit and 10 to 12 days after detecting the urinary luteinizing hormone surge, all women were subjected to a blood sample and to an endometrial biopsy. Progesterone and estrogen levels were measured in serum and in endometrial tissue and receptor concentrations were in the endometrial sample.
Results Women with recurrent miscarriage showed significantly lower concentration of receptors in both the cytoplasm and the nucleus of endometrial tissue compared with controls. The nuclear/cytoplasm ratio of progesterone receptor was significantly higher in cases compared with controls, implicating that recurrent miscarriage is probably linked to nongenomic activity of the hormone; this was also significant for estrogen receptor. Serum progesterone and estrogen hormonal levels were comparable between groups while both hormones were significantly reduced in the endometrium of recurrent miscarriage cases. Receptors significantly correlated with endometrial hormonal level but not to serum level.
Conclusion Recurrent miscarriage might be linked to reduced endometrial progesterone and estrogen receptors and appears to be more related to nongenomic activity of progesterone. Endometrial receptors expression correlates to tissue hormonal level rather than to serum hormonal level.