bluuebunny/crossref_metadata_2025_split huggingface dataset:
Accurate estimation of concrete consumption in tunnel lining using terrestrial laser scanning
Authors: Jian Liao , Qiu Wenge , Cheng Yunjian 
Published: February 2024

AbstractAccurate estimation of concrete (including shotcrete) consumption plays a crucial role in tunnel construction. A novel method has been introduced to accurately estimate concrete consumption with terrestrial laser scanning (TLS). The estimation needs to capture TLS data of tunnel surfaces at different stages of construction. Unrolling point clouds, a novel two-stage algorithm consisting of noise removal and hole filling has been used to generate resampled points. Furthermore, resampled points from two scans (before and after lining construction) ultimately generate an innovative computation model composed of multiple hexahedral elements, which is used for calculating volumes. The proposed technique was applied to the Tiantaishan highway tunnel and Da Fang Shan high-speed railway tunnel. The calculation relative error of the rebound rate is 0.19%, and the average relative error in predicting the demand for secondary lining concrete is 0.15%. Compared with 3D Delaunay with curve fitting, the proposed technique offers a more straightforward operation and higher accuracy. Considering factors such as tunnel geometry, support design, and concrete properties, a computational model will provide valuable insights into optimizing resource allocation and reducing material waste during construction.
Exploration of nonlinear optical properties of 4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-phenylpropanamide based derivatives: experimental and DFT approach
Authors: Irfan Muhammad , Khan Hammad Ali , Bibi Shamsa , Wu Gang , Ali Akbar , Khan Samreen Gul , Alhokbany Norah , Rasool Faiz , Chen Ke 
Published: February 2024

AbstractTriazoles, nitrogen-containing heterocycles, have gained attention for their applications in medicinal chemistry, drug discovery, agrochemicals, and material sciences. In the current study, we synthesized novel derivatives of N-substituted 2-((5-(3-bromophenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)-N-phenylpropanamide and conducted a comprehensive investigation using density functional theory (DFT). These novel structural hybrids of 1,2,4-triazole were synthesized through the multi-step chemical modifications of 3-bromobenzoic acid (1). Initially, compound 1 was converted into its methyl-3-bromobenzoate (2) which was then transformed into 3-bromobenzohydrazide (3). The final step involved the cyclization of compound 3, producing its 1,2,4-triazole derivative (4). This intermediate was then coupled with different electrophiles, resulting in the formation of the final derivatives (7a–7c). Additionally, the characterization of these triazole-based compounds (7a, 7b, and 7c) were carried out using techniques such as IR, HNMR, and UV–visible spectroscopy to understand their structural and spectroscopic properties. The DFT study utilized M06/6-311G(d,p) functional to investigate geometrical parameters, HOMO–LUMO energies, natural bond orbital analyses, transition density matrix (TDM), density of states, and nonlinear optical (NLO) properties. The FMO analysis revealed that compound 7c exhibited the lowest band gap value (4.618 eV). Notably, compound 7c exhibited significant linear polarizability (4.195 >  × 10–23) and first and second hyperpolarizabilities (6.317 >  × 10–30, 4.314 × 10–35), signifying its potential for nonlinear optical applications. These NLO characteristics imply that each of our compounds, especially 7c, plays a crucial part in fabricating materials showing promising NLO properties for optoelectronic applications.
Near-infrared spectroscopy for kidney oxygen monitoring in a porcine model of hemorrhagic shock, hemodilution, and REBOA
Authors: Silverton Natalie A. , Lofgren Lars R. , Kuck Kai , Stoddard Gregory J. , Johnson Russel , Ramezani Ali , Hoareau Guillaume L. 
Published: February 2024

AbstractAcute kidney injury is a common complication of trauma and hemorrhagic shock. In a porcine model of hemorrhagic shock, resuscitative endovascular balloon aortic occlusion (REBOA) and hemodilution, we hypothesized that invasive kidney oxygen concentration measurements would correlate more strongly with noninvasive near infra-red spectroscopy (NIRS) oxygen saturation measurements when cutaneous sensors were placed over the kidney under ultrasound guidance compared to placement over the thigh muscle and subcutaneous tissue. Eight anesthetized swine underwent hemorrhagic shock 4 of which were resuscitated with intravenous fluids prior to the return of shed blood (Hemodilution protocol) and 4 of which underwent REBOA prior to resuscitation and return of shed blood (REBOA protocol). There was a moderate correlation between the NIRS and kidney tissue oxygen measurements (r = 0.61 p < 0.001; r = 0.67 p < 0.001; r = 0.66 p < 0.001for left kidney, right kidney, and thigh NIRS respectively). When the animals were separated by protocol, the Hemodilution group showed a weak or nonsignificant correlation between NIRS and kidney tissue oxygen measurements (r = 0.10 p < 0.001; r = 0.01 p = 0.1007; r = 0.28 p < 0.001 for left kidney, right kidney, and thigh NIRS respectively). This contrasts with the REBOA group, where left and right kidney as well as thigh NIRS were moderately correlated with kidney tissue oxygen (r = 0.71 p < 0.001; r = 0.74 p < 0.001; r = 0.70 p < 0.001; for left kidney, right kidney, and thigh NIRS respectively). There was a strong correlation between both kidney NIRS signals and thigh NIRS measurements (r = 0.85 p < 0.001; r = 0.88 p < 0.001;for left kidney vs thigh and right kidney vs thigh respectively). There was also a strong correlation between left and right kidney NIRS (r = 0.90 p < 0.001). These relationships were maintained regardless of the resuscitation protocol. These results suggest that kidney NIRS measurements were more closely related to thigh NIRS measurements than invasive kidney tissue oxygen concentration.
Exploring the links of skeletal muscle mitochondrial oxidative capacity, physical functionality, and mental well-being of cancer survivors
Authors: Gonsalves Stephen G. , Saligan Leorey N. , Bergeron Christopher M. , Lee Philip R. , Fishbein Kenneth W. , Spencer Richard G. , Zampino Marta , Sun Xinyi , Sheng Jennifer Yeong-Shin , Stearns Vered , Carducci Michael , Ferrucci Luigi , Lukkahatai Nada 
Published: February 2024

AbstractPhysical impairments following cancer treatment have been linked with the toxic effects of these treatments on muscle mass and strength, through their deleterious effects on skeletal muscle mitochondrial oxidative capacity. Accordingly, we designed the present study to explore relationships of skeletal muscle mitochondrial oxidative capacity with physical performance and perceived cancer-related psychosocial experiences of cancer survivors. We assessed skeletal muscle mitochondrial oxidative capacity using in vivo phosphorus-31 magnetic resonance spectroscopy (31P MRS), measuring the postexercise phosphocreatine resynthesis time constant, τPCr, in 11 post-chemotherapy participants aged 34–70 years. During the MRS procedure, participants performed rapid ballistic knee extension exercise to deplete phosphocreatine (PCr); hence, measuring the primary study outcome, which was the recovery rate of PCr (τPCr). Patient-reported outcomes of psychosocial symptoms and well-being were assessed using the Patient-Reported Outcomes Measurement Information System and the 36-Item Short Form health survey (SF-36). Rapid bioenergetic recovery, reflected through a smaller value of τPCr was associated with worse depression (rho ρ = − 0.69, p = 0.018, and Cohen’s d = − 1.104), anxiety (ρ = − 0.61, p = .046, d = − 0.677), and overall mental health (ρ = 0.74, p = 0.010, d = 2.198) scores, but better resilience (ρ = 0.65, p = 0.029), and coping-self efficacy (ρ = 0.63, p = 0.04) scores. This is the first study to link skeletal muscle mitochondrial oxidative capacity with subjective reports of cancer-related behavioral toxicities. Further investigations are warranted to confirm these findings probing into the role of disease status and personal attributes in these preliminary results.
Generation WhatsApp: inter-brain synchrony during face-to-face and texting communication
Authors: Schwartz Linoy , Levy Jonathan , Hayut Olga , Netzer Ofir , Endevelt-Shapira Yaara , Feldman Ruth 
Published: February 2024

AbstractTexting has become one of the most prevalent ways to interact socially, particularly among youth; however, the effects of text messaging on social brain functioning are unknown. Guided by the biobehavioral synchrony frame, this pre-registered study utilized hyperscanning EEG to evaluate interbrain synchrony during face-to-face versus texting interactions. Participants included 65 mother-adolescent dyads observed during face-to-face conversation compared to texting from different rooms. Results indicate that both face-to-face and texting communication elicit significant neural synchrony compared to surrogate data, demonstrating for the first time brain-to-brain synchrony during texting. Direct comparison between the two interactions highlighted 8 fronto-temporal interbrain links that were significantly stronger in the face-to-face interaction compared to texting. Our findings suggest that partners co-create a fronto-temporal network of inter-brain connections during live social exchanges. The degree of improvement in the partners' right-frontal-right-frontal connectivity from texting to the live social interaction correlated with greater behavioral synchrony, suggesting that this well-researched neural connection may be specific to face-to-face communication. Our findings suggest that while technology-based communication allows humans to synchronize from afar, face-to-face interactions remain the superior mode of communication for interpersonal connection. We conclude by discussing the potential benefits and drawbacks of the pervasive use of texting, particularly among youth.
Fingertip tactile sensation via piezoelectric micromachined ultrasonic transducers with an amplified interface
Authors: Sone Junji 
Published: February 2024

AbstractTactile devices are often used in the field of robotics; however, the development of compact high-resolution tactile devices remains challenging. In this study, we developed a haptic device for force presentation using a DC motor and a tactile sensation device to simultaneously present haptic and tactile stimuli. A microelectromechanical system was selected to maintain the compactness of the tactile device. Piezoelectric micromachined ultrasonic transducers are known for high-power stimulation, and we selected lanthanum-doped lead zirconate titanate as the high-power amplified actuator. A finger mount structure that transfers force for amplifying ultrasonic waves was considered to combine acoustic pressure and aeroacoustics by attaching silicone rubber. The device was fabricated, and the performance of the tactile sensations was evaluated. The developed device uses the novel concept of combining acoustic pressure and aeroacoustics, and its compactness renders it suitable for wearable systems.
Comparing domain- and intensity-specific physical activity in coronary heart disease and non-CHD individuals
Authors: Goo Seon Young , Lee Mi Kyung , Lee Dong Hoon , Park Dong - Hyuk , Lee Tae Ho , Lee Chan Joo , Lee Jong-Young , Jeon Justin Y. 
Published: February 2024

AbstractAlthough increase in physical activity is important to improve prognosis of cardiac patients in addition to hospital-based exercise cardiac rehabilitation, their physical activity levels are not properly understood. This study aimed to examine domain- and intensity-specific physical activity in individuals with coronary heart disease (CHD) and compare them with non-CHD individuals. Data from the Korean National Health and Nutrition Examination Survey (KNHANES) from 2014 to 2019 were analyzed, including 1083 CHD patients and 38,532 non-CHD individuals. The inclusion criteria were age 19 years or older and data not missing for CHD information. Before and after propensity score matching (PSM) for age, sex, body mass index, education, household income, alcohol intake, and smoking status, domain (leisure, work, transportation)—and intensity (moderate, vigorous) -specific physical activity participation levels were compared between individuals with and without CHD. Before PSM, CHD individuals were older, less educated, more sedentary, and participated less in PAs compared to non-CHD individuals. After PSM, CHD individuals had similar levels of domain-specific PAs. However, they had higher work-related PA levels (29.7 ± 209.6 vs. 42.1 ± 291.3 min/week p = 0.022) and more sedentary time (487.2 ± 224.2 vs. 514.1 ± 228.7. p = 0.003) than those without CHD. Subgroup analysis revealed lower leisure-related PA in men with CHD (63.5 ± 165.5 vs. 47.3 ± 140.2, p < 0.05) and higher work-related PA in women with CHD (18.9 ± 159.7 vs. 57.1 ± 397.5, p < 0.01). Among those < 65 years of age, individuals with CHD spent more time sedentary than individuals without CHD. CHD individuals are not physically inactive compared with non-CHD individuals who are similar in sociodemographic status and lifestyle. CHD patients’ PA levels may have been underestimated.
Detection of novel drug-adverse drug reaction signals in rheumatoid arthritis and ankylosing spondylitis: analysis of Korean real-world biologics registry data
Authors: Kwon M. , Joung C. I. , Shin H. , Lee C. C. , Song Y. S. , Lee Y. J. , Kang S. , Kim J. Y. , Lee S. 
Published: February 2024

AbstractThis study aimed to detect signals of adverse drug reactions (ADRs) associated with biological disease-modifying antirheumatic drugs (DMARDs) and targeted therapies in rheumatoid arthritis (RA) and ankylosing spondylitis (AS) patients. Utilizing the KOrean College of Rheumatology BIOlogics & Targeted Therapy Registry (KOBIO) data, we calculated relative risks, excluded previously reported drug-ADR pairs, and externally validated remaining pairs using US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) and single centre’s electronic health records (EHR) data. Analyzing data from 2279 RA and 1940 AS patients, we identified 35 significant drug-ADR pairs in RA and 26 in AS, previously unreported in drug labels. Among the novel drug-ADR pairs from KOBIO, 15 were also significant in the FAERS data. Additionally, 2 significant drug-laboratory abnormality pairs were found in RA using CDM MetaLAB analysis. Our findings contribute to the identification of 14 novel drug-ADR signals, expanding our understanding of potential adverse effects related to biological DMARDs and targeted therapies in RA and AS. These results emphasize the importance of ongoing pharmacovigilance for patient safety and optimal therapeutic interventions.
Droplet impact on doubly re-entrant structures
Authors: Singh Navdeep Sangeet , Jitniyom Thanaphun , Navarro-Cía Miguel , Gao Nan 
Published: February 2024

AbstractDoubly re-entrant pillars have been demonstrated to possess superior static and dynamic liquid repellency against highly wettable liquids compared to straight or re-entrant pillars. Nevertheless, there has been little insight into how the key structural parameters of doubly re-entrant pillars influence the hydrodynamics of impacting droplets. In this work, we carried out numerical simulations and experimental studies to portray the fundamental physical phenomena that can explain the alteration of the surface wettability from adjusting the design parameters of the doubly re-entrant pillars. On the one hand, three-dimensional multiphase flow simulations of droplet impact were conducted to probe the predominance of the overhang structure in dynamic liquid repellency. On the other hand, the numerical results of droplet impact behaviours are agreed by the experimental results for different pitch sizes and contact angles. Furthermore, the dimensions of the doubly re-entrant pillars, including the height, diameter, overhang length and overhang thickness, were altered to establish their effect on droplet repellency. These findings present the opportunity for manipulations of droplet behaviours by means of improving the critical dimensional parameters of doubly re-entrant structures.
Improving the quality properties of soybean oil by using rice bran oil
Authors: Mohammed Ahmed Sabry , Hashem Hanafy Abdel Aziz , Abdel Maksoud Badr Saed 
Published: February 2024

AbstractThis study aims to study the effect of substituting soybean oil (SO) with rice bran oil (RBO) at different levels (25%, 50%, and 75%) on the physical and chemical properties, fatty acid composition, and oxidative stability of SO, also, study the effect of storing SO, RBO, and their blend oils at ambient temperature for a period of 12 months on the content of free fatty acids (% FFA), peroxide value (PV), and thiobarbituric acid (TBA). RBO demonstrated good quality, as evidenced by its initial low values of % FFA, PV, and TBA. Furthermore, RBO was found to be an excellent source of γ-oryzanol, whereas the other oils lacked this compound. Consequently, increasing the proportion of RBO in SO resulted in the least degradation, while pure SO exhibited the highest degree of degradation. Moreover, the blend oils demonstrated an inhibitory effect against oxidation, allowing for a prolonged storage period without the use of industrial antioxidants. Throughout the entire storage period, the % FFA and PV of all tested blend oil samples remained within the limits recommended for human consumption. TBA exhibited a similar trend to PV. However, an incremental increase in TBA values was observed as the storage period of the oils extended. In SO, TBA levels increased from 0.533 mg malonaldehyde/kg oil at the beginning to 1.446 mg malonaldehyde/kg oil after 12 months of storage. In RBO, TBA levels increased from 0.336 mg malonaldehyde/kg oil at the beginning to 0.882 mg malonaldehyde/kg oil after 12 months of storage.
Wireless body area sensor networks based human activity recognition using deep learning
Authors: El-Adawi Ehab , Essa Ehab , Handosa Mohamed , Elmougy Samir 
Published: February 2024

AbstractIn the healthcare sector, the health status and biological, and physical activity of the patient are monitored among different sensors that collect the required information about these activities using Wireless body area network (WBAN) architecture. Sensor-based human activity recognition (HAR), which offers remarkable qualities of ease and privacy, has drawn increasing attention from researchers with the growth of the Internet of Things (IoT) and wearable technology. Deep learning has the ability to extract high-dimensional information automatically, making end-to-end learning. The most significant obstacles to computer vision, particularly convolutional neural networks (CNNs), are the effect of the environment background, camera shielding, and other variables. This paper aims to propose and develop a new HAR system in WBAN dependence on the Gramian angular field (GAF) and DenseNet. Once the necessary signals are obtained, the input signals undergo pre-processing through artifact removal and median filtering. In the initial stage, the time series data captured by the sensors undergoes a conversion process, transforming it into 2-dimensional images by using the GAF algorithm. Then, DenseNet automatically makes the processes and integrates the data collected from diverse sensors. The experiment results show that the proposed method achieves the best outcomes in which it achieves 97.83% accuracy, 97.83% F-measure, and 97.64 Matthews correlation coefficient (MCC).
Calcium carbonate precipitating extremophilic bacteria in an Alpine ice cave
Authors: Lange-Enyedi Nóra Tünde , Németh Péter , Borsodi Andrea K. , Spötl Christoph , Makk Judit 
Published: February 2024

AbstractExtensive research has provided a wealth of data on prokaryotes in caves and their role in biogeochemical cycles. Ice caves in carbonate rocks, however, remain enigmatic environments with limited knowledge of their microbial taxonomic composition. In this study, bacterial and archaeal communities of the Obstans Ice Cave (Carnic Alps, Southern Austria) were analyzed by next-generation amplicon sequencing and by cultivation of bacterial strains at 10 °C and studying their metabolism. The most abundant bacterial taxa were uncultured Burkholderiaceae and Brevundimonas spp. in the drip water, Flavobacterium, Alkanindiges and Polaromonas spp. in the ice, Pseudonocardia, Blastocatella spp., uncultured Pyrinomonadaceae and Sphingomonadaceae in carbonate precipitates, and uncultured Gemmatimonadaceae and Longimicrobiaceae in clastic cave sediments. These taxa are psychrotolerant/psychrophilic and chemoorganotrophic bacteria. On a medium with Mg2+/Ca2+ = 1 at 21 °C and 10 °C, 65% and 35% of the cultivated strains precipitated carbonates, respectively. The first ~ 200 µm-size crystals appeared 2 and 6 weeks after the start of the cultivation experiments at 21 °C and 10 °C, respectively. The crystal structure of these microbially induced carbonate precipitates and their Mg-content are strongly influenced by the Mg2+/Ca2+ ratio of the culture medium. These results suggest that the high diversity of prokaryotic communities detected in cryogenic subsurface environments actively contributes to carbonate precipitation, despite living at the physical limit of the presence of liquid water.
Distribution of multi-level B cell subsets in thymoma and thymoma-associated myasthenia gravis
Authors: Zhang Peng , Liu Yuxin , Chen Si , Zhang Xinyu , Wang Yuanguo , Zhang Hui , Li Jian , Yang Zhaoyu , Xiong Kai , Duan Shuning , Zhang Zeyang , Wang Yan , Wang Ping 
Published: February 2024

AbstractB-cell subsets in peripheral blood (PB) and tumor microenvironment (TME) were evaluated to determine myasthenia gravis (MG) severity in patients with thymoma-associated MG (TMG) and the distribution of B cells in type B TMG. The distribution of mature B cells, including Bm1–Bm5, CD19+ and CD20+ B cells and non-switched (NSMBCs) and switched (SMBCs) memory B cells, were determined in 79 patients with thymoma or TMG. Quantitative relationships between the T and TMG groups and the TMG-low and TMG-high subgroups were determined. NSMBCs and SMBCs were compared in TME and PB. Type B thymoma was more likely to develop into MG, with types B2 and B3 being especially associated with MG worsening. The percentage of CD19+ B cells in PB gradually increased, whereas the percentage of CD20+ B cells and the CD19/CD20 ratio were not altered. The (Bm2 + Bm2′)/(eBm5 + Bm5) index was significantly higher in the TMG-high than in thymoma group. The difference between SMBC/CD19+ and NSMBC/CD19+ B cell ratios was significantly lower in the thymoma than TMG group. NSMBCs assembled around tertiary lymphoid tissue in thymomas of patients with TMG. Few NSMBCs were observed in patients with thymoma alone, with these cells being diffusely distributed. MG severity in patients with TMG can be determined by measuring CD19+ B cells and Bm1-Bm5 in PB. The CD19/CD20 ratio is a marker of disease severity in TMG patients. Differences between NSMBCs and SMBCs in PB and TME of thymomas can synergistically determine MG severity in patients with TMG.