bluuebunny/crossref_metadata_2025_split huggingface dataset:
SOSIALISASI RENCANA PENGEMBANGAN DESA WISATA KAMPUNG TERAPUNG UNTUK MENINGKATKAN PARIWISATA DAN PEREKONOMIAN PRODUKTIF DI DESA LOKBAINTAN LUAR
Authors: Dyah Sri Wulandari  , Dedek Yahya Darmadi  , Saidatun Nisa  , Angga Irawan  
Published: February 2024

ABSTRAK: Lok Baintan adalah salah satu desa di Kecamatan Sungai Tabuk, Kabupaten Banjar, Provinsi Kalimantan Selatan, Indonesia. Desa ini terkenal dengan Pasar Terapung Lok Baintan. Mata pencaharian yang berada di Desa Lok Baintan sebagian besar yaitu seperti pedagang dan petani. Perdagangan merupakan mayoritas pencaharian penduduk khususnya di pasar terapung Lok Baintan. Barang yang di jual di pasar terapung ini berbagai macam seperti buah-buahan, sayur-sayuran dan lain-lain yang di petik dari hasil pertanian yang kemudian dijual di pasar terapung Lok Baintan luar. Hasil dari yang diperjual belikan di pasar terapung Lok Baintan didapatkan langsung sebagian besarnya dari bertani masyarakat setempat. Masalah yang didapatkan adalah masyarakat mengeluh bahwa menurunnya jumlah kunjungan wisatawan dipasar terapung Lok Baintan Luar hal ini disebabkan sebagian pedagang maupun penjual telah berpindah tempat ke pasar terapung di daerah lain sehingga perlunya pengembangan desa demi mengembalikan minat wisatawan untuk datang kembali ke Desa Lok Baintan Luar, melalui program ini penulis memberikan beberapa solusi yaitu dengan memberikan pengetahuan mengenai Desa Wisata dan cara mengembangkan Kawasan Desa dengan mewujudkan terciptanya Desa Wisata Kampung Terapung, dengan harapan inovasi yang dilakukan dapat meningkatkan pertumbuhan ekonomi masyarakat
Kata kunci : Pasar Terapung, Desa Wisata, Kampung Terapung, Pertumbuhan Ekonomi

ABSTRACT: Lok Baintan is a village in Sungai Tabuk District, Banjar Regency, South Kalimantan Province, Indonesia. This village is famous for the Lok Baintan Floating Market. Most of the livelihoods in Lok Baintan Village are traders and farmers. Trade is the majority of the population's livelihood, especially in the Lok Baintan floating market. Goods that are sold in this floating market are various kinds such as fruits, vegetables and others which are picked from agricultural products which are then sold in the outer Lok Baintan floating market. Most of the results that are traded at the Lok Baintan floating market are obtained directly from the farming of the local community. The problem found is that people complain that the decrease in the number of tourist visits to the Lok Baintan Luar floating market is due to the fact that some traders and sellers have moved to floating markets in other areas so that the need for village development is to restore tourist interest in coming back to Lokbaintan Luar Village, through the program In this article, the author provides several solutions, namely by providing knowledge about Tourism Villages and how to develop Village Areas by realizing the creation of a Floating Village Tourism Village, with the hope that the innovations carried out can increase the economic growth of the community
Keywords: Floating Market, Tourism Village, Floating Village, Economic Growth
Keanekaragaman Arthropoda Permukaan Tanah Pada Pertanaman Bawang Merah (Allium ascalonicum L.) Pada Lahan Gambut yang Diaplikasikan Kulit Jengkol
Authors: Fahri Fahri , Rosa Helda Orbani , Aidawati Noor 
Published: February 2024

Shallots are a spice commodity that is very important in everyday life. Shallots are one of the commodities that greatly influence the level of economic inflation. This commodity experienced a decline in production of 101%. In 2017 it could produce 28,456 quintals while in 2018 it produced 14,155 quintals. This can be caused by several things that exist in the environment around the plantation. This research aims to determine the diversity of arthropods in Allium ascalonicum shallot plantings. This research was carried out from October - to December 2021 on Tegal Arum Village Land, Banjarbaru City. The research method uses an exploration method carried out directly at the location of the shallot trap plantation and treated with jengkol (Archidendron pauciflorum) skin powder using a Pitfall ground surface trap. The calculation results of the traps installed trapped 239 arthropods belonging to 5 orders, Coleoptera, Orthoptera, Hymenoptera, Dermaptera, and Araneae.
On the Trail of Lost Ingredients
Authors: Broecke Lara Abigail 
Published: February 2024

This paper addresses the question of translation as research. Using examples from Cennino Cennini’s Libro dell’arte and the 15th century Bolognese Manuscript, written in Italian and Latin, the author uses case studies to exemplify the use of secondary literature, dictionaries and comparative evidence from within the manuscript itself for the identification of materials. The author concludes that translation imposes a very strict discipline, which constrains the translator to push lexical research to its limits.Este documento aborda la cuestión de la traducción como investigación. Utilizando ejemplos del Libro dell'arte de Cennino Cennini y el manuscrito boloñés del siglo XV, escritos en italiano y latín, el autor utiliza estudios de caso para ejemplificar el uso de literatura secundaria, diccionarios y evidencia comparativa del interior del propio manuscrito para la identificación de materiales. El autor concluye que la traducción impone una disciplina muy estricta, que obliga al traductor a llevar la investigación léxica a sus límites.
Development of a competitive chemiluminescent assay for quantitative determination of TP53 fusion protein using reagent strips
Authors: wang Linyu , He Zhifang , Li Jianye 
Published: February 2024

Abstract
Recent studies have shown that almost half of all cancers occur due to DNA damage. For the early diagnosis of cancer, a highly sensitized and swift identification for TP53 is needed since the corresponding TP53 protein is effectively recognized as “the guardian of the genome.” To improve the detection sensitivity, numerous analytical methods were previously used for the determination of the TP53 protein, including denaturing high-performance liquid chromatography and enzyme-linked immunosorbent assay (ELISA). Currently, immunochromatographic tests (ICTS) that are simple to use, stable over time, and show low interference are regarded as valuable tools for the quick screening of food and environmental monitoring along with clinical diagnosis. ICTS often have limited sensitivity even if a variety of novel reporters possessing optimum photostability and improved brightness are used as the signal-intensity reporters. Compared with N-(4-aminobutyl)-N-(ethylisoluminol) or luminol, a novel luminescent probe, 2',6'-diMethyl-4'-(N-succiniMidyloxycarbonyl) phenyl-10-sulfopropylacridiniuM-9-carboxylate (NSP-DMAE-NHS) has achieved a much higher efficiency, improvement in the biosensor's performance, and amplification of the signal without causing any damage to the biomolecule in terms of its biochemical activity. In this study, the reagent strip method was initially used to detect TP53 fusion protein by combining the advantages of NSP-DMAE-NHS and immunochromatography. In our experiment, the control and study lines on the strips were immobilized through HRP-conjugated goat anti-rabbit IgG and TP53 antigen, respectively. The optimized concentration of the anti-TP53 antibody-NSP-DMAE-NHS immunoconjugates was then added to the TP53 antigen samples. After, the test strips were inserted and left in the aforementioned buffer solution for an additional 20 minutes. Finally, a lab made luminous measurement device was used to analyze the corresponding control and study lines on the strips. Under optimized conditions, this method was found to be ultrasensitive, with a wide range of linear responses from 0.0008 ng mL-1 to 1 µg mL-1 and a limit of detection of 0.0008 ng mL-1 (0.013 pM). Thus, a novel competitive chemiluminescent assay based on reagent strips was established for the determination of the TP53 fusion proteins. The strategy has potential applications for ultrasensitive detection in the early diagnosis of cancer.
WITHDRAWN: Magnetic Resonance Spectroscopy Displays the Structural and Biochemical Effects of Spinal Manipulative Therapy in Lumbar Discogenic Pain: a case report
Authors: Billham Jessica F , Roland Erika Evans , Gornet Matthew F. , Brinkman Kelly , Schranck Francine , Cox Jim , Kettner Norman W. 
Published: February 2024

Abstract

The full text of this preprint has been withdrawn by the authors as it was submitted and made public without the full consent of all the authors. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Goldbach Conjecture Proof
Authors: Thompson Daniel 
Published: February 2024

Abstract
The Goldbach conjecture was proposed by the German mathematician Christian Goldbach around the year 1742, to another well-known mathematician of that time Leonard Euler. The conjecture has been found to hold for all numbers up to 4 x 10⁸, but remains unproven until now. This paper proves the Goldbach conjecture by showing that elements of the addition of two odd prime numbers produce elements of the resulting even number. The resulting elements from the addition of two odd prime numbers evaluate to an equal amount thus proving that every even number can be expressed as the addition of two odd prime numbers.
MSC: 11-xx.
A Linear Approximate Robust Strategic Asset Allocation with Inflation-Deflation Hedging Demand
Authors: Kusuda Koji , Kikuchi Kentaro 
Published: February 2024

Abstract
This study considers a finite-time consumption-investment problem for investors with homothetic robust utility under the quadratic security market model with stochastic volatilities and inflation rates. This leads to a nonlinear nonhomogeneous partial differential equation for indirect utility. We propose a linear approximation method and derive the approximate optimal robust portfolio decomposed into myopic, intertemporal hedging, and inflation-deflation hedging demands. Furthermore, we propose a method for estimating our quadratic security market model that stabilizes the optimal portfolio estimates. We then apply our estimation method to a two-factor quadratic security market model. Our numerical analysis shows i) the linear approximate optimal portfolio is highly accurate and ii) the market timing effects in the optimal robust allocation are significant and nonlinear, and are mainly due to inflation-deflation hedging demand in addition to myopic demand.
Evaluation of resistance of corn varieties to Dalbulus Maidis (Delong &amp; Wolcott) (Hemiptera: Cicadellidae)
Authors: de Souza Ruana Regina Negrão , Marques Rodrigo Neves 
Published: February 2024

Abstract
The aim of this study was to evaluate the resistance of 10 corn varieties to Dalbulus maidis. The attractiveness of corn plants to D. maidis for feeding and/or shelter, as well as oviposition with and without choice, was examined. The effects on the development stages of D. maidis in different varieties and the damage caused by D. maidis in corn plants were assessed. The IAC AIRAN and Amarelo Astecão varieties showed the highest mean preference by adults compared to Pipoca Roxo Kika, which was the least preferred. For oviposition with a choice, there was no statistically significant difference, but for oviposition without a choice, more eggs were laid on Al Bandeirante compared to Amarelo Astecão. Insects maintained on NS 90 PRO 2 plants exhibited the longest nymphal period, and those on Pipoca Roxo Kika had the longest developmental period compared to insects on Branco Pedro 2. Insects on Amarelo Laleska, Amarelo Astecão, NS 90 PRO 2, Pipoca Roxo Kika, and Vermelho Pedro showed the shortest longevities compared to insects on Al Bandeirante. Growth percentage data and visual damage scale did not show statistically significant differences. A dendrogram indicated the formation of two major groups: susceptible varieties and resistant varieties. The results of this research may have identified sources of resistance in corn plants, which could assist in controlling D. maidis, guide the selection of materials for cultivation in the field, and inform corn breeding programs.
Examining the Predictive Precision of Open-Source Simulators for Boosting Reliability and Widespread Acceptance: Thermodynamic Insights into Ethane Dehydrogenation
Authors: OYEGOKE Toyese 
Published: February 2024

Abstract

Process simulators remain integral to training engineers across industries, encompassing nuclear, petrochemical, biochemical, and chemical sectors. Their role in teaching various chemical engineering disciplines, including design, integration, thermodynamics, safety, and separation processes, is invaluable. While most simulators are commercial, known for user-friendliness and global confidence, their high costs limit accessibility for low-income schools. In contrast, freeware simulators, though less recognized, present a cost-effective alternative. This study compares the predictive capabilities of commercial and freeware simulators, demonstrating the reliability of open-source options. The recommendation emerges to instruct process engineers using affordable freeware simulators, particularly in economically challenged regions where research funding is scarce.
Organic Matrices of Calcium Carbonate Biominerals Improve Osteoblastic Mineralization
Authors: Nahle Sarah , Lutet-Toti Camille , Namikawa Yuto , Piet Marie-Hélène , Brion Alice , Peyroche Sylvie , Suzuki Michio , Marin Frédéric , Rousseau Marthe 
Published: February 2024

Abstract

Many organisms incorporate inorganic solids into their tissues to improve functional and mechanical properties. The resulting mineralized tissues are called biominerals. Several studies have shown that nacreous biominerals induce osteoblastic extracellular mineralization. Among them, Pinctada margaritifera is well known for the ability of its organic matrix to stimulate bone cells. In this context, we aimed to study the effects of shell extracts from three other Pinctada species (Pinctada radiata, Pinctada maxima, and Pinctada fucata) on osteoblastic extracellular matrix mineralization, by using an in vitro model of mouse osteoblastic precursor cells (MC3T3-E1). For a better understanding of the Pinctada-bone mineralization relationship, we evaluated the effects of 4 other nacreous mollusks that are phylogenetically distant and distinct from the pinctadas. In addition, we tested 12 non-nacreous mollusks and one extra-group. Biomineral shell powders were prepared, and their organic matrix was partially extracted using ethanol. Firstly, the effect of these powders and extracts was assessed on the viability of MC3T3-E1. Our results indicated that neither the powder nor the ethanol-soluble matrix (ESM) affected cell viability at low concentrations. Then, we evaluated osteoblastic mineralization using Alizarin Red staining and we found a prominent MC3T3-E1 mineralization mainly induced by nacreous biominerals, especially those belonging to the Pinctada genus. However, few non-nacreous biominerals were also able to stimulate the extracellular mineralization. Overall, our findings validate the remarkable ability of CaCO3 biomineral extracts to promote bone mineralization. Nevertheless, further in vitro and in vivo studies are needed to uncover the mechanisms of action of biominerals in bone.
Biological response to endodontic treatment in one versus two-visit: a systematic review and meta- analysis of animal studies
Authors: Neto Raimundo Sales de Oliveira , Souza Thais de Moraes , Rosa Stefani Jovedi , Vivan Rodrigo Ricci , Alcalde Murilo Priori , Honório Heitor Marques , Duarte Marco Antonio Hungaro 
Published: February 2024

Abstract
OBJECTIVES
To perform a systematic review of animal studies that compared the histopathological characteristics between teeth with apical periodontitis after endodontic treatment in one or two visits.
MATERIAL AND METHODS
This systematic review was registered on the International Prospective Register of Systematic Reviews (PROSPERO) – CRD42022340849. Studies were collected from PubMed/MEDLINE, LILACS, EMBASE, Livivo, SciELO, Web of Science, Scopus, and Cochrane Library and manual and gray literature searches. Animal studies that evaluated histological characteristics after endodontic treatment of teeth with apical periodontitis in one or two visits were included. Risk of bias analysis of the included studies was performed using the Systematic Review Centre for Laboratory Animal Experimentation (SYRCLE) tool. Data synthesis of the included studies with quantitative data was performed, and meta-analysis was conducted with the Comprehensive Meta-Analysis software, using the random effects model and odds ratio (OR).
RESULTS
Eighteen studies met the inclusion criteria (Kappa = 0.891). Meta-analyses indicated values in inflammatory infiltrate intensity with effect size of 5.5% (95% CI: 0.020–0.148; p < 0.001), periodontal ligament thickness: 25.6% (95% CI: 0.134–0.487; p < 0.001), dentin resorption: 13% (95% CI: 0.015–1.141; p = 0.066), cementum resorption: 7.1% (95% CI: 0.015–0.325; p = 0.001), bone resorption: 1.4% (95% CI: 0.002–0.130; p < 0.001), mineralized tissue resorption: 42.8% (95% CI: 0.110–1.671; p = 0.222), biological apical sealing: 13.1% (95% CI: 0.055–0.314; p < 0.001), and presence of microorganisms: 10.3% (95% CI: 0.014–0.747; p = 0.025).
CONCLUSIONS
The two-visit endodontic treatment, using calcium hydroxide-based intracanal medication, resulted in better biological repair characteristics.
CLINICAL RELEVANCE:
A two-visit endodontic treatment with calcium hydroxide-based intracanal medication yields superior histopathological outcomes.
Co-application of titanium nanoparticles and melatonin effectively lowered chromium toxicity in lemon balm (Melissa officinalis L.) through modifying biochemical characteristics
Authors: soliman Mona H. , Alghanem Suliman M.S. , Alsudays Ibtisam M. , Alaklabi Abdullah , Alharbi Basmah M. , Al-Amrah Hadba , Azab Ehab , Alnusairi Ghalia S.H. 
Published: February 2024

Abstract
Chromium (Cr) toxicity can negatively affect plant growth and development, impacting agricultural productivity and posing risks to human health. Metallic nanoparticles (MNPs) such as titanium dioxide (TiO2) and natural growth regulators such as melatonin (MT) become promising technology to manage heavy metal-contaminated soils and promote safe food production. The present work was conducted to find the effect of foliar application of TiO2 NPs (15 Mg L− 1) and MT (100 µM) on growth, biochemical attributes, and Cr accumulation in plant tissues of melissa officinalis L. under Cr toxicity (50 and 100 mg Cr kg − 1 soil). The results showed that Cr toxicity led to decreased plant performance, where 100 mg Cr kg − 1 soil led to notable decreases in shoot weight (28%), root weight (27%), essential oil (EO) yield (34%), chlorophyll (Chl) a + b (33%), while increased malondialdehyde (MDA, 30%), superoxide dismutase (SOD) activity (51%), and catalase (CAT) activity (122%). The use of TiO2 NPs and MT, particularly their co-application, remarkably reduced Cr toxicity by enhancing plant weight, Chl content, and lowered MDA and antioxidant activity. Total phenolic content (TPC), total flavonoid content(TFC), EO percentage, and rosmarinic acid in plants treated with Cr at 50 mg Cr kg − 1 soil and co-application of TiO2 NPs and MT were relatively higher than in other treatments. Under 100 mg Cr kg − 1 soil, the synergic effect of TiO2 NPs and MT enhanced rosmarinic acid content (22%) but lowered Cr accumulation in roots (51%) and shoots (72%). Heat map analysis showed that ACT, SOD, MDA, and EO yield had the maximum variability under Cr, TiO2 NPs, and MT. Exogenous TiO2 NPs and MT can be recommended to modulate Cr toxicity in lemon balm under soil Cr toxicity.
Distinct functions of parvalbumin and somatostatin interneurons in the anterior cingulate cortex result in heterogeneity of social interaction impairments
Authors: Wu Shengxi , Qi Chuchu , Sima Wenqi , Miao Honghui , Hu Erling , Ge Junye , Deng Mao , Chen Andi , Ye Weiyi , Xue Qian , Wang Wenting , Chen Qian 
Published: February 2024

Abstract
The anterior cingulate cortex (ACC) serves as a core region in social networks, and impairments in this area have been identified in autism spectrum disorders. Our prior research demonstrated that deficits in pyramidal neurons in ACC adversely impacted mouse social interaction. The preservation of functional output in the ACC by pyramidal neurons relies on the dynamic regulation by the different types of interneurons. However, the precise regulatory roles of distinct interneurons within the ACC in shaping social interaction have hitherto remained largely enigmatic. In this study, we elucidated the involvement of parvalbumin (PV) and somatostatin (SST) interneurons within the ACC in modulating social interaction behavior. Specifically, we ascertain that PV interneurons play a more prominent role in initiating sociability, whereas SST interneurons uniquely influence social preference. Notably, the downregulation of the autism high-risk gene Kcnh7 is identified in both PV and SST interneurons within the Shank3 knockout (KO) autistic mouse model. Further, the selective KO of Kcnh7 in PV- or SST-positive neurons contributes to disruptions in sociability and social preference, respectively. The divergent modulation of social interaction by PV and SST interneurons in the ACC is attributed to the distinct input received by these neuronal subtypes. Our findings offer nuanced insights into the multifaceted roles of PV and SST neurons within the ACC in the context of social interaction, contributing to a comprehensive understanding of the neurobiological underpinnings of social behavior disorders in autism. The delineation of these mechanisms is imperative for advancing our comprehension of the etiological basis of autism, thereby paving the way for novel avenues of research aimed at addressing the heterogeneous phenotypes associated with social interaction dysfunction in cortical interneurons.
Polyketide synthase-derived sphingolipids determine microbiota-mediated protection against pathogens in C. elegans
Authors: Peters* Lena , Drechsler* Moritz , Pees Barbara , Angelidou Georgia , Salzer Liesa , Moors Karlis Arturs , Paczia Nicole , Schulenburg Hinrich , Shi Yi-Ming , Kaleta Christoph , Witting Michael , Bode** Helge B. , Dierking** Katja 
Published: February 2024

Abstract
Protection against pathogens is a major function of the gut microbiota. Although bacterial natural products have emerged as crucial components of host-microbiota interactions, their exact role in microbiota-mediated protection is largely unexplored. We addressed this knowledge gap with the nematode Caenorhabditis elegans and its microbiota isolate Pseudomonas fluorescens MYb115 that is known to protect against Bacillus thuringiensis (Bt) infection. We find that MYb115-mediated protection depends on sphingolipids that are derived from an iterative type I polyketide synthase (PKS), thereby describing a noncanonical pathway of bacterial sphingolipid production. We provide evidence that MYb115-derived sphingolipids affect C. elegans tolerance to Bt infection by altering host sphingolipid metabolism. This work establishes sphingolipids as structural outputs of bacterial PKS and highlights the role of microbiota-derived sphingolipids in host protection against pathogens.

*/** shared first or last authorship