bluuebunny/crossref_metadata_2025_split huggingface dataset:
Edukasi Gizi Isi Piringku dan Perilaku Hidup Bersih dan Sehat (PHBS) Sebagai Upaya Penurunan dan Pencegahan Stunting Di Desa Suka Menanti Kecamatan Bukit Kemuning Kabupaten Lampung Utara
Authors: Bertalina  , Sutrio  
Published: December 2023

Stunting is a condition of failure to thrive in children under five due to chronic malnutrition. Stunting occurs due to multifactors, namely household and family factors such as knowledge, upbringing, food availability and poor sanitation, inadequate breastfeeding and complementary breastfeeding, infection factors such as history of malaria, diarrhea and incomplete immunization, as well as community and social factors such as economic conditions, health services and culture, so efforts to reduce stunting are not only a task for the health sector, but also across sectors.
The purpose of this Community Service Implementation is to increase the knowledge of mothers, prospective brides, pregnant women and cadres about stunting prevention through education on Fill My Plate and PHBS. Target activities for pregnant women, prospective brides and mothers with children under five, and family companions.
The method used is counseling about stunting and demonstrations of the contents of my plate and PHBS. The results obtained by all participants increased knowledge and awareness about stunting and participants were able to practice My Plate Fill and PHBS. It is hoped that the village government can carry out periodic outreach and monitor and assist stunting toddlers. Health workers are also expected to improve health services for prospective brides, pregnant women, babies and toddlers by providing support to catin to get education about health, pregnant women to check their pregnancies regularly, encouraging exclusive breastfeeding and providing additional food. The community also needs to contribute to preventing stunting by adopting a clean and healthy lifestyle.
Edukasi Tentang Sehat dan Bugar dengan Gizi Seimbang Saat Anak Berpuasa
Authors: Wahyuni Endang Sri , Bertalina  
Published: December 2023

Fasting is an obligation for every mature Muslim. In addition to carrying out obligations, fasting provides benefits in the form of increasing immunity, training children's discipline, training children to be able to control themselves and be patient. Kindergarten-aged children need to be trained to fast so that they are able to fast when the obligation reaches them. Community service activities aim to increase the knowledge of parents/guardians of students, teachers at TKIT Setia, about nutrition for children while fasting
The method used is education about balanced nutrition when children are fasting, which is delivered through lectures and questions and answers. Education was also carried out with a competition to make a healthy cone by the parents/guardians of the students. The education was attended by 41 parents/guardians and teachers, and the tumpeng contest was attended by 9 groups.
Education increases the knowledge of parents/guardians of students about children's food during fasting. At the end of the delivery of the material, participants can answer oral questions submitted by the speaker. Several tumpeng contested did not meet the requirements for balanced nutrition
Polypharmacy and drug-drug interactions among patients with Diabetes Mellitus
Authors: ÖZYİĞİT Filiz , PAŞALI KİLİT Türkan , ONBAŞI Kevser 
Published: December 2023

Background: Diabetes mellitus is a chronic disease. The aim of our study was to evaluate drug- drug interactions and polypharmacy in diabetic patients.
Methods: Patients with type 2 diabetes attending our internal medicine and endocrinology policlinics from April 2019 to July 2019 were included to the study. It was designed as a prospective, descriptive and cross-sectional study. The socio-demographic characteristics of diabetic individuals, the drugs they use in the treatment of diabetes, and other accompanying diseases were evaluated according to the ATC classification. In this study, interactions between multiple drugs and polypharmacy were examined.
Results: The study population consisted of 526 patients between the ages of 18-87/years (59 ± 11). 69.6% of the patients were women.83.8% of the patients had chronic diseases accompanying diabetes. The most common chronic diseases were hypertension (53.6%), hyperlipidemia (41.4%) and coronary artery disease (27.2%), respectively. 45.01% of the patients were using five or more drugs. The mean number of drugs was found to be 4.49 ± 1.93. Among the drugs used by the patients, 787 drug-drug interactions were found in a total of 429 (81.5%) patients. The average number of interactions was 3.89 ± 3.6 for interaction A 15.2% (n = 81), 16.2% (n = 85) for interaction B, 69.8% (n = 367) for interaction C was, 47.9% (n = 252) for interaction D, and 0.4% (n = 2) for interaction X. The most frequent interaction was found between acetylsalicylic acid and insulin and metformin and angiotensin converting enzyme inhibitors.
Conclusions: Both the polypharmacy rate and drug-drug interaction rate are high in diabetic patients. The most common type of interaction is type C and type D drug-drug interaction. Attention should be paid to drug-drug interactions in the treatment of diabetes patients.
Penyuluhan E-Commerce Sebagai Alternatif Media Pemasaran Hasil Produk Desa Lokasi Baru Dalam Menunjang Rencana Desa Wisata
Authors: Windirah Nola , Mulyasari Gita , Yuliarso M Zulkarnain 
Published: December 2023

Pengembangan desa wisata membantu desa dalam menjadikan lingkungan atau potensi alam terjaga bahkan dapat meningkatkan kualitas alam itu sendiri. Teknologi informasi bisa dimanfaatkan dengan efektif untuk pengembangan desa wisata apabila pengelola dapat menggunakan teknologi tersebut dengan baik. Oleh karena itu, penting bagi pengelola desa wisata memiliki pemahaman terhadap kegunaan teknologi informasi dan salah satunya adalah melalui e-commerce. Desa Lokasi Baru Kecamatan Sukaraja Kabupaten Seluma menjadi salah satu yang bergerak aktif dalam pengelolaan potensi desa melalui BumDes untuk terwujudnya pembentukan desa wisata. Desa Lokasi Baru telah memiliki beberapa unit usaha seperti kerajinan rajutan dan olahan koran bekas, makanan Bipang manis, sajian wisata berupa kola seluas 0,5 hektar, kebun desa dan aktivitas penggemukan sapi yang dpat dijadikan unit-unit pendukung dalam mewujudkan desa wisata. Namun, beberapa unit usaha yang telah dijalankan mengalami permasalahan yang sama berupa keterbatasan dalam pemasaran produk. Penyuluhan e-commerce yang dilakukan bertujuan untuk meningkatkan pengetahuan dan kemampuan digital masyarakat dalam memasarkan berbagai produk potensial desa. Hasil kegiatan menunjukkan antusias masyarakat cukup tinggi tercermin dari keaktifan dalam berdiskusi.
La formación de subjetividades emocionales infantiles en la educación temprana
Authors: Cárdenas Forero Óscar Leonardo , Gaitán Plaza Yerly Viviana , González Hernández Natalia , Leal Peña Estefanía 
Published: December 2023

Durante el estado de confinamiento mundial provocado por la aparición del virus del Covid-19, y tiempo después de esta situación, se comenzó a percibir en la escuela un inusitado interés y un incremento exagerado por las emociones infantiles, y una preocupación desmedida por diseñar alternativas para lograr su óptimo desarrollo. La pandemia tuvo un impacto particular en el desarrollo emocional, al punto que, los maestros, los niños y las niñas tuvieron que adaptarse rápidamente a situaciones inesperadas como el aislamiento social, la comunicación a distancia, el uso de metodologías digitales y la preocupación por la salud física, mental y emocional.
La e escuela se vio obligada a utilizar herramientas y prácticas electrónicas sin un tiempo adecuado de transición, lo que generó un cambio abrupto en la vida de los estudiantes y en su forma de ver y de relacionarse con el mundo. En esta perspectiva, el presente artículo, utilizando una visión foucaultiana y, basándose en la exploración documental, describe en clave de sospecha el proceso de formación de subjetividades emocionales infantiles durante y luego de la pandemia. Revelando preliminarmente que, si bien es cierto, la dimensión emocional se vio afectada en este tiempo, curiosamente, también se hizo natural su existencia, otorgarle un valor insólito, como condición esencial para formar tempranamente sujetos emocionales y para optimizar los aprendizajes.
Comparative Study on Estimation Methods of Proportional Hazard Models for Interval-Censored Data
Authors: Keita Sonobe , Shimokawa Asanao , Miyaoka Etsuo 
Published: December 2023

Purpose: In this study, we compare the estimation methods of interval-censored data using both simulated and real data. Many past studies have used fixed sample sizes in their simulation studies. We performed the best possible simulation study.
Method: The methods include Finkelstein’s method with Piecewise and Spline and imputation methods (i.e., Efron’s method in the Cox model).
Results: If the interval-censored data do not overlap, the same estimation results are obtained regardless of the assignment point for the estimation of the Cox model. The overlapping data also did not significantly affect the accuracy of the estimation. On the other hand, Finkelstein’s method showed differences in estimation depending on the two estimation methods of the baseline survival function. Although it was not possible to determine which method had better power, the Spline method had a smaller absolute error than the Finkelstein method. A comparison of Cox’s and Finkelstein’s methods showed that Finkelstein’s method was superior in terms of power.
Conclusion: Interval-censored data is a form of data that can be found in a variety of fields. In this study, we compared estimation methods for interval-censored data, and the usefulness of Finkelstein’s method can be seen from simulation studies.
Developing a multi-institutional nomogram for assessing lung cancer risk in patients with 5–30 mm pulmonary nodules: a retrospective analysis
Authors: Jiang Yongjie , Deng Taibing , Huang Yuyan , Ren Bi , He Liping , Pang Min , Jiang Li 
Published: December 2023

Background
The diagnosis of benign and malignant solitary pulmonary nodules based on personal experience has several limitations. Therefore, this study aims to establish a nomogram for the diagnosis of benign and malignant solitary pulmonary nodules using clinical information and computed tomography (CT) results.

Methods
Retrospectively, we collected clinical and CT characteristics of 1,160 patients with pulmonary nodules in Guang’an People’s Hospital and the hospital affiliated with North Sichuan Medical College between 2019 and 2021. Among these patients, data from 773 patients with pulmonary nodules were used as the training set. We used the least absolute shrinkage and selection operator (LASSO) to optimize clinical and imaging features and performed a multivariate logistic regression to identify features with independent predictive ability to develop the nomogram model. The area under the receiver operating characteristic curve (AUC), C-index, decision curve analysis, and calibration plot were used to evaluate the performance of the nomogram model in terms of predictive ability, discrimination, calibration, and clinical utility. Finally, data from 387 patients with pulmonary nodules were utilized for validation.

Results
In the training set, the predictors for the nomogram were gender, density of the nodule, nodule diameter, lobulation, calcification, vacuole, vascular convergence, bronchiole, and pleural traction, selected through LASSO and logistic regression analysis. The resulting model had a C-index of 0.842 (95% CI [0.812–0.872]) and AUCs of 0.842 (95% CI [0.812–0.872]). In the validation set, the C-index was 0.856 (95% CI [0.811–0.901]), and the AUCs were 0.844 (95% CI [0.797–0.891]). Results from the calibration curve and clinical decision curve analyses indicate that the nomogram has a high fit and clinical benefit in both the training and validation sets.

Conclusion
The establishment of a nomogram for predicting the benign or malignant diagnosis of solitary pulmonary nodules by this study has shown good efficacy. Such a nomogram may help to guide the diagnosis, follow-up, and treatment of patients.
Field Assessment of Morphometric and Agronomic Characteristics of Fifteen Groundnut (Arachis hypogaea L.) Varieties Under Agroecological Conditions of INERA Gimbi station, Democratic Republic of Congo
Authors: Kabwe-Milolo G. , Kalonji-Mbangila A. , Kabangu J. Mudibu wa , Mwabila M. Lufuluabo , Muengula-Manyi M. , Kalonji-Mbuyi A. 
Published: December 2023

Aim: To evaluate morphometric and agronomic traits of fifteen groundnut varieties from germplasm of the National Pulses Program of Institut National pour l’Etude et la Recherche Agronomiques.
Study Design: This study was conducted using a randomized complete block design (RCBD) with fifteen treatments repeated three times.
Place and duration of the study: The trial was conducted at Gimbi research station from March 9 to June 13, 2022.
Methodology: This study was conducted using fifteen varieties (treatments) replicated three times. Data collected concerned the percentage of seedlings that emerged, morphometric and agronomic parameters.
Results: Seeds emerged varied from 80.6 to 93.5%. Collar diameter varied from 8.7 to 10.1mm, and stem height from 40.5 to 55.1cm. Groundnut varieties flowered on 30 to 35 DAS, and pod maturity is reached on 90 to 98 DAS. Number of pods per plant varied from 10.2 to 16.6, and number of seeds per pod from 2.0 to 2.3. The weight of fresh pods per plot varied from 1,002.3 to 1,043.2g, and the weight of dry pods per plot from 742.3 to 858.7g. The 100-seed weight varied from 49.4 to 53.4g. Dry pods yield varied from 1,546.5 to 1,816.1kg/ha, and seeds yield from 1,376.8 to 1,642.4kg/ha. The principal component analysis figure explains reality with 55.32% information. The first axis explained explains 33.54% of the information, and the second axis explained explains 21.78% of the information. Ascending hierarchical classification grouped groundnut varieties into five classes.
Conclusion: This study shows high variability in the behaviour of groundnut varieties used. Collar diameter and plant height development are continuous from the second to the eighth WAS, then practically fade from the tenth WAS. Groundnut varieties flowered, and pods reached maturity at the same time. Yield is positively correlated with the weight of dry pods and the weight of seeds per plot. Hierarchical classification revealed five distinct classes of groundnut varieties.
Effect of Micronutrients on Productivity and Profitability of Pea (Pisum sativum sub sp. hortense)
Authors: Pal Ratan Kumar , Pal A. K. , Chaurasiya Rajkumar , Bharadwaj Moomal , Sharma Ankur 
Published: December 2023

A field experiment was conducted to investigate the effects of micronutrients on productivity and profitability of pea (Pisum sativum sub sp. hortense) at the Vegetable Research Farm, Department of Horticulture, Institute of Agricultural Sciences, Banaras Hindu University, Varanasi, during the winter season of 2019- 2020. The experiment was laid out in the Randomized Block Design comprising of 9 treatments including control with different concentrations of boron and zinc applied to the pea crop viz., Control, Boron-20(0.06%), Boron-20(0.09%), ZnSo4 (0.03%), ZnSo4 (0.05%), Boron-20(0.06%) + ZnSo4(0.03%), Boron-20(0.06%) + ZnSo4(0.05%), Boron-20(0.09%)+ ZnSo4(0.03%) and Boron-20(0.09%)+ZnSo4 (0.05%) which were replicated thrice. Garden Pea variety “Azad Pea-3” was sown at row to row spacing of 30 cm x plant to plant spacing of 10 cm. The crop was uniformly fertilized by 20 kg N, 40 kg P2O5, 40 kg K2O /ha through urea and diammonium phosphate and muriate of potash. However, Zinc and boron was applied through zinc sulphate and borax as per the requirement of the treatments. The results indicated that the application B-20(0.09%) + ZnSO4(0.05%) recorded the highest quantity of seeds per pod (9.27g) number of pods per plant (25.63), yield per plant (64.23g), fruit yield (135.37 q/ha) which was closely followed by application of B-20(0.09%)+ZnSO4(0.03%). Further, application B-20(0.09%) + ZnSO4(0.05%) recoded higher B:C ratio (4.06) as compared to control (2.72). Thus, application of B-20(0.09%) + ZnSO4(0.05%) was found to the best treatment among all the treatments in improving the productivity of garden pea for the resource poor farmers of India.
Predicting the population viability of an endangered amphibian under environmental and demographic uncertainty
Authors: Brooks George C. , Chandler Houston C. , Jiao Yan , Childs Dylan Z. , Haas Carola A. 
Published: December 2023

AbstractPopulation viability analyses (PVAs) represent a key component of many recovery plans for threatened and endangered species. Demography links the processes that affect individuals to population‐level patterns, and hence projections constructed from demographic data are the most common tools for PVAs. We constructed a size‐structured integral projection model (IPM) for the United States federally endangered Reticulated Flatwoods Salamander, Ambystoma bishopi, to evaluate demographic influences on population growth and predict the efficacy of future management actions. Flatwoods salamanders breed in ephemeral wetlands in the Southeastern United States. The ephemeral nature of breeding sites can result in complete recruitment failure in drought years when wetlands fail to fill, or dry before metamorphosis occurs. As a result, this species exhibits marked temporal variability in vital rates that must be accounted for in projection models. We constructed a stochastic IPM using 13 years of mark‐recapture data (2010–2023) from two breeding wetlands. Variable survival rates exhibited by flatwoods salamanders, coupled with a high probability of recruitment failure, result in a low predicted probability of population persistence. Sensitivity analyses revealed age at maturity and the frequency of recruitment exerted the greatest influence on population growth, and thus managers should prioritize conservation efforts that target these demographic processes. Additional management should consider strategies to dampen temporal variability in larval survival, something that could be achieved through emergency salvage operations, captive rearing efforts, and manipulation of wetland hydroperiods.
Infliximab in neurosarcoidosis: a systematic review and meta‐analysis
Authors: Chaiyanarm Siwakorn , Satiraphan Piraya , Apiraksattaykul Natnasak , Jitprapaikulsan Jiraporn , Owattanapanich Weerapat , Rungjirajittranon Tarinee , Nanthasi Witsarut 
Published: December 2023

AbstractObjectivesTo evaluate the clinical outcomes and relapse rates in neurosarcoidosis patients administered infliximab.MethodsA systematic review was conducted using the MEDLINE, EMBASE, SCOPUS, and Cochrane Library databases. The search included studies from their inception to March 2023. We included case‐series studies with at least 10 neurosarcoidosis patients undergoing any treatment type. Studies were also required to report at least one of the following outcomes: response rate, overall survival rate, or relapse rate. This study adhered to the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines. A random‐effects model facilitated the analysis of proportional treatment outcomes. Study quality was evaluated using the modified Newcastle–Ottawa quality assessment scale, while a funnel plot helped detect any publication bias.ResultsSeven studies comprising 237 patients with neurosarcoidosis were included in the analysis. Of these patients, 184 (77.6%) received treatment with infliximab. The pooled proportion of patients showing clinical improvement after infliximab treatment was 0.74 (95% CI 0.64–0.84, I2 = 49.73%). Relapse rates, derived from four studies, stood at 0.38 (95% CI 0.22–0.55, I2 = 56.92%). Most studies reported successful tapering or cessation of corticosteroid dosage in patients receiving infliximab. Adverse effects were reported in 52 (29.4%) patients, of which 39 out of 54 events (72.2%) were linked to infections.InterpretationInfliximab demonstrated potential improvement in clinical outcomes for patients with refractory neurosarcoidosis and showed potential for reducing the dosage of concurrent corticosteroids. However, a degree of relapse was observed, with infections being the primary concern for adverse events.
Single Metal Atoms Anchored on N‐Doped Holey Graphene as Efficient Dual‐Active‐Component Catalysts for Nitroarene Reduction
Authors: Hu Hanyu , Liu Pei , Cao Sufeng , You Liming , Zhang Ning , Xi Jiangbo , Guo Sheng , Zhou Kun 
Published: December 2023

AbstractDeveloping efficient catalysts for facilitating organic synthesis processes is a popular but challenging topic in modern chemical industries. A combination of active metals and an active support structure is, in theory, an effective strategy for boosting catalytic activity but such combinations have been rarely explored. Herein, a strategy for fabricating highly efficient dual‐active‐component catalysts (DACCs) is presented by anchoring single‐atom metals (M1; e.g., Pd1, Ni1, Co1, and Zn1) or double‐atomic metals (e.g., Pd1‐Co1, Pd1‐Ru1, and Pd1‐Ni1) on nitrogen‐doped holey graphene (NHG). Among the resultant DACCs, Pd1/NHG, which combines atomically dispersed metal species and an active NHG carbocatalyst, has been shown to display enhanced catalytic performance toward nitroarene reduction . In particular, its catalytic efficiency in reducing 4‐nitrophenol corresponds to a turnover frequency of 2.0 min−1, which is 97 times higher than the benchmark set by commercial Pd/C catalysts (5.0 wt.%), and vastly superior to those of its counterparts (e.g., NHG carbocatalyst and NHG supported Pd clusters. Notably, four intermediates and two active components (i.e., NHG and single‐atom Pd) in the nitroarene reduction process have been identified. This study presents an effective and versatile synthetic strategy to prepare DACCs through the combination of metallic catalysts and a carbocatalyst substrate.
Printed Electronic Devices and Systems for Interfacing with Single Cells up to Organoids
Authors: Saghafi Mahsa K. , Vasantham Srivatsan K. , Hussain Navid , Mathew George , Colombo Federico , Schamberger Barbara , Pohl Eric , Marques Gabriel Cadilha , Breitung Ben , Tanaka Motomu , Bastmeyer Martin , Selhuber‐Unkel Christine , Schepers Ute , Hirtz Michael , Aghassi‐Hagmann Jasmin 
Published: December 2023

AbstractThe field of bioelectronics with the aim to contact cells, cell clusters, biological tissues and organoids has become a vast enterprise. Currently, it is mainly relying on classical micro‐ and nanofabrication methods to build devices and systems. Very recently the field is highly pushed by the development of novel printable organic, inorganic and biomaterials as well as advanced digital printing technologies such as laser and inkjet printing employed in this endeavor. Recent advantages in alternative additive manufacturing and 3D printing methods enable interesting new routes, in particular for applications requiring the incorporation of delicate biomaterials or creation of 3D scaffold structures that show a high potential for bioelectronics and building of hybrid bio‐/inorganic devices. Here the current state of printed 2D and 3D electronic structures and related lithography techniques for the interfacing of electronic devices with biological systems are reviewed. The focus lies on in vitro applications for interfacing single cell, cell clusters, and organoids. Challenges and future prospects are discussed for all‐printed hybrid bio/electronic systems targeting biomedical research, diagnostics, and health monitoring.