bluuebunny/crossref_metadata_2025_split huggingface dataset:
Online Aphasia Groups: Navigating Issues of Voice and Identity
Authors: Azios Jamie H. , Lee Jaime B. , Sigur Anna , Archer Brent , Elman Roberta J. 
Published: December 2023

Purpose:Participation in aphasia groups is associated with increased communication, reduced feelings of social isolation, and increased quality of life. Despite the growing popularity of online aphasia groups, little is known about how to manage conversation in this format. We examined online aphasia book club sessions to examine how the facilitator supported group members' participation in conversation.Method:Interactional sociolinguistic discourse analysis was used to analyze the behaviors and actions of the facilitator and group members. Qualitative data for this study were drawn from four recorded online aphasia book club sessions held through a university's free aphasia clinic on the Zoom web-conferencing platform.Results:Sociolinguistic discourse analysis revealed strategic facilitator behaviors that served to (a) give members with varying levels of verbal language abilities voice, (b) foreground or background aspects of voice, and (c) minimize her own voice to promote interactional symmetry between herself and group members.Conclusions:Identity formed the backdrop for facilitators' actions when leading online groups, guiding decisions about who got to talk, when, for how long, through what modality, and about what topics. A better understanding of the interactions that occur online, such as how to develop and protect the identities of group members, could equip facilitators with the tools necessary for facilitating positive, engaging aphasia therapy groups online.
Linking Oropharyngeal Swallowing Physiology and Functional Clinical Predictors in Amyotrophic Lateral Sclerosis
Authors: Garand Kendrea L. (Focht) , Malek Angela M. , Ambrocio Kevin Renz 
Published: December 2023

Purpose:
We aimed to quantify oropharyngeal swallowing physiology in amyotrophic lateral sclerosis (ALS) and examine relationships between swallowing impairments and ratings of pulmonary function (forced vital capacity percent predicted, FVC % pre) and functional status (ALS Functional Rating Scale–Revised, ALSFRS-R).

Method:

A retrospective analysis of swallowing-related data of persons with ALS (PALS) was completed. Their Modified Barium Swallow Impairment Profile component, Oral Total (OT), and Pharyngeal Total (PT) scores were compared with data from age- (±1 year) and sex-matched healthy controls retrieved from an archival normative data set using Mann–Whitney
U
tests. Relationships between PALS' OT and PT scores, FVC % pre, and ALSFRS-R were examined using Pearson product–moment correlations and multiple linear regression modeling.

Results:

Twenty-one PALS (12 women), with a mean age of 62.2 ± 9.9 years, were included in the analyses. Compared to healthy controls, PALS exhibited significantly worse function across 13 (76%) physiological swallowing components (all
p
< .05). OT and PT scores significantly differed between PALS and healthy controls (each
p
< .001), with higher scores (worse impairment) observed in the former. When adjusting for age and sex, FVC % pre was a significant predictor of OT score (
p
= .045). An inverse relationship was found with ALSFRS-R and OT score (
p
= .052). FVC % pre (
p
= .061) and ALSFRS-R (
p
= .54) did not significantly predict PT score.

Conclusions:
PALS demonstrated swallowing impairments across oropharyngeal domains and the esophageal component. In our PALS cohort, FVC % pre was a useful clinical indicator of oral swallowing impairment.
Improved thermal hydraulic network modelling and error analysis in disc‐type transformer windings
Authors: Wang Yuan , Shi Chaoqun , Gao Meng , Xu Yang , Fu Mingli , Zhuo Ran 
Published: December 2023

AbstractTemperature distribution in transformer windings is a crucial factor that influences the safe operation, and lifespan of an insulating system in an oil‐immersed power transformer. Thermal hydraulic network modelling (THNM) has been the subject of numerous studies because of its lower computation cost as compared to a computational fluid dynamics (CFD) simulation. This study proposes improvements to THNM, with primary focus on non‐uniformity of temperatures in the entry and exit vertical oil ducts, and the feasibility of using a piecewise fitting formula for Nusselt number (Nu) of convection heat transfer coefficient in transformer windings. The deviation of hot spot temperature was 0.3°C, and the location of hot spot for CFD and THNM was 34th disc and 35th disc, respectively. The calculation time of CFD and THNM was about 34 h and 35 s under the same computer hardware situations. This provides an acceptable THNM method for the rapid prediction of transformer hot spot temperature and location at low costs for digital twin.
Congestion control in constrained Internet of Things networks
Authors: Mhamdi Lotfi , Abdul Khalek Hussam 
Published: December 2023

AbstractThe Internet of Things (IoT) is a growing technology that remotely connects multiple devices (ranging across many fields and applications) over the Internet. The scalability of an IoT network mandates a reliable transport infrastructure. Traditional transport control protocol (TCP) control protocol is unsuitable for such domain, mainly due to energy and power consumption reasons. A lighter version of TCP, light weight IP (lwIP) provides a promising solution for current and projected future scalable IoT infrastructures. However, the original lwIP is just a simple mapping of the protocol, without insight into the IoT specific requirements. This paper examines the lwIP congestion control mechanism and addresses its shortcomings. In particular, a detailed examination is devoted to the various metrics such as retransmission time‐outs and its back‐off epochs, the congestion window behaviour and progress in the absence (and presence) of congestion. In particular, we propose a set of novel algorithms to address both the IoT constraints nature (light‐weight) as well as keeping up with scalability in IoT network size and performance. A detailed simulation study has been conducted to endorse the viability of our proposed set of algorithms for next‐generation IoT networks.
Vertical shear instability in two-moment radiation-hydrodynamical simulations of irradiated protoplanetary disks
Authors: Melon Fuksman Julio David , Flock Mario , Klahr Hubert 
Published: December 2023

Context. The vertical shear instability (VSI) is a hydrodynamical instability predicted to produce turbulence in magnetically inactive regions of protoplanetary disks. The regions in which this instability can occur and the physical phenomena leading to its saturation are a current matter of research.
Aims. We explore the secondary instabilities triggered by the nonlinear evolution of the VSI and their role in its saturation. We also expand on previous investigations on stability regions by considering temperature stratifications enforced by stellar irradiation and radiative cooling, and including the effects of dust-gas collisions and molecular line emission.
Methods. We modeled the gas-dust mixture in a circumstellar disk around a T Tauri star by means of high-resolution axisymmetric radiation-hydrodynamical simulations including stellar irradiation with frequency-dependent opacities, considering different degrees of depletion of small dust grains.
Results. The flow pattern produced by the interplay of the axisymmetric VSI modes and the baroclinic torque forms bands of nearly uniform specific angular momentum. In the high-shear regions in between these bands, the Kelvin–Helmholtz instability (KHI) is triggered. A third instability mechanism, consisting of an amplification of eddies by baroclinic torques, forms meridional vortices with Mach numbers up to ∼0.4. Our stability analysis suggests that protoplanetary disks can be VSI-unstable in surface layers up to tens of au for reasonably high gas emissivities.
Conclusions. The significant transfer of kinetic energy to small-scale eddies produced by the KHI and possibly even the baroclinic acceleration of eddies limit the maximum energy of the VSI modes, likely leading to the saturation of the VSI. Depending on the gas molecular composition, the VSI can operate at surface layers even in regions where the midplane is stable. This picture is consistent with current observations of disks showing thin midplane millimeter-sized dust layers while appearing vertically extended in optical and near-infrared wavelengths.
The variety of extreme blazars in the AstroSat view
Authors: Goswami P. , Zacharias M. , Zech A. , Chandra S. , Boettcher M. , Sushch I. 
Published: December 2023

Context. Among the blazar class, extreme blazars have exceptionally hard intrinsic X-ray/TeV spectra, and extreme peak energies in their spectral energy distribution (SED). Observational evidence suggests that the non-thermal emission from extreme blazars is typically non-variable. All these unique features present a challenging case for blazar emission models, especially regarding those sources with hard TeV spectra.
Aims. We aim to explore the X-ray and GeV observational features of a variety of extreme blazars, including extreme-TeV, extreme-synchrotron (extreme-Syn), and regular high-frequency-peaked BL Lac objects (HBLs). Furthermore, we aim to test the applicability of various blazar emission models that could explain the very hard TeV spectra.
Methods. We conducted a detailed spectral analysis of X-ray data collected with AstroSat and Swift-XRT, along with quasi-simultaneous γ-ray data from Fermi-LAT, for five sources: 1ES 0120+340, RGB J0710+591, 1ES 1101−232, 1ES 1741+196, and 1ES 2322−409. We took three approaches to modelling the SEDs: (1) a steady-state one-zone synchrotron-self-Compton (SSC) code, (2) another leptonic scenario of co-accelerated electrons and protons on multiple shocks applied to the extreme-TeV sources only (e–p co-acceleration scenario), and (3) a one-zone hadro-leptonic (ONEHALE) code. The latter code is used twice to explain the γ-ray emission process: proton synchrotron and synchrotron emission of secondary pairs.
Results. Our X-ray analysis provides well-constrained estimates of the synchrotron peak energies for both 1ES0120+340 and 1ES1741+196. These findings categorise these latter objects as extreme-synchrotron sources, as they consistently exhibit peak energies above 1 keV in different flux states. The multi-epoch X-ray and GeV data reveal spectral and flux variabilities in RGB J0710+591 and 1ES 1741+196, even on timescales of days to weeks. As anticipated, the one-zone SSC model adequately reproduces the SEDs of regular HBLs but encounters difficulties in explaining the hardest TeV emission. Hadronic models offer a reasonable fit to the hard TeV spectrum, though with the trade-off of requiring extreme jet powers. On the other hand, the lepto-hadronic scenario faces additional challenges in fitting the GeV spectra of extreme-TeV sources. Finally, the e–p co-acceleration scenario naturally accounts for the observed hard electron distributions and effectively matches the hardest TeV spectrum of RGB J0710+591 and 1ES 1101−232.
Retraction Note: Ankrd36 Inhibits Nuclear Factor-κB Activation and Inflammation in Mice Aortic Endothelial Cells
Authors: Xue Yuanyuan 
Published: December 2023

The authors have expressed the wish to retract this article on the ground that they have inadvertently used material without proper authorization. They apologized for the inconvenience caused.
The Publisher and Editor(s) approved to the retraction.
A Bayesian approach to the drag-based modelling of ICMEs
Authors: Chierichini Simone , Francisco Gregoire , Mugatwala Ronish , Foldes Raffaello , Camporeale Enrico , De Gasperis Giancarlo , Giovannelli Luca , Napoletano Gianluca , Del Moro Dario , Erdelyi Robertus 
Published: December 2023

Coronal Mass Ejections (CMEs) are huge clouds of magnetised plasma expelled from the solar corona that can travel towards the Earth and cause significant space weather effects. The Drag-Based Model (DBM) describes the propagation of CMEs in an ambient solar wind as analogous to an aerodynamic drag. The drag-based approximation is popular because it is a simple analytical model that depends only on two parameters, the drag parameter $ \gamma $ and the solar wind speed $ w$. DBM thus allows us to obtain reliable estimates of CME transit time at low computational cost. Previous works proposed a probabilistic version of DBM, the Probabilistic Drag Based Model (P-DBM), which enables the evaluation of the uncertainties associated with the predictions. In this work, we infer the “a-posteriori” probability distribution functions (PDFs) of the $ \gamma $ and $ w$ parameters of the DBM by exploiting a well-established Bayesian inference technique: the Monte Carlo Markov Chains (MCMC) method. By utilizing this Bayesian method through two different approaches, an ensemble and an individual approach, we obtain specific DBM parameter PDFs for two ensembles of CMEs: those travelling with fast and slow solar wind, respectively. Subsequently, we assess the operational applicability of the model by forecasting the arrival time of CMEs. While the ensemble approach displays notable limitations, the individual approach yields promising results, demonstrating competitive performances compared to the current state-of-the-art, with a Mean Absolute Error (MAE) of 9.86 ± 4.07 h achieved in the best-case scenario.
A stag beetle knife can achieve stabler and safer endoscopic submucosal dissection in the esophagus
Authors: Funasaka Kohei , Horiguchi Noriyuki , Yamada Hyuga , Koyama Keishi , Tahara Tomomitsu , Nagasaka Mitsuo , Nakagawa Yoshihito , Ohno Eizaburo , Kuzuya Teiiji , Miyahara Ryoji , Shibata Tomoyuki , Hirooka Yoshiki 
Published: December 2023

Abstract
Background and study aims Esophageal endoscopic submucosal dissection (ESD) has a higher complication rate than gastric ESD. Scissor-type devices, including the stag beetle (SB) knife, are reportedly safer and have shorter procedure times than tip devices. To clarify the characteristics of the SB knife, we compared the treatment outcomes of esophageal ESD with a tip-type knife to those with an SB knife combination.
Patients and methods Between January 2016 and March 2023, clinical data from 197 lesions in 178 patients who underwent esophageal ESD were analyzed retrospectively. Every lesion was assigned to either the tip-type group or the SB group based on the devices with which the submucosa was initially dissected. We compared procedure time and complications and analyzed the risk of muscular exposure using multivariate analysis.
Results Procedure time was not significantly different between the tip-type and SB groups (60.3±42.2 min vs. 58.8±29.1 min). The variation in procedure time was significant according to F test P=0.002). Incidence of muscular exposure was significantly lower in the SB group than in the tip-type group (24.5% vs. 11.1%, P=0.016). These differences were significant in resected specimens larger than 21 mm. Procedure time over 60 minutes (odds ratio [OR] 2.5, 95% confidence interval [CI]: 1.15–5.42, P=0.02) was a risk factor for muscular exposure, and submucosal dissection with an SB knife was a safety factor (OR 0.4, 95% CI: 0.18–0.89, P=0.02).
Conclusions Performing esophageal ESD with an SB knife is a safe procedure with less variation in procedure time and less muscule exposure.
Risk of Depression after Venous Thromboembolism in Patients with Hematological Cancer: A Population-Based Cohort Study
Authors: Steiner Daniel , Horváth-Puhó Erzsébet , Jørgensen Helle , Laugesen Kristina , Ay Cihan , Sørensen Henrik Toft 
Published: December 2023

Background Venous thromboembolism (VTE) may complicate the clinical course of cancer patients and add to their psychological burden.
Objectives We aimed to investigate the association between VTE and risk of subsequent depression in patients with hematological cancer.
Patients and Methods We conducted a population-based cohort study using Danish national health registries. Between 1995 and 2020, we identified 1,190 patients with hematological cancer and incident VTE diagnosed within 6 months before to 1 year after cancer diagnosis. A comparison cohort of patients with hematological cancer without VTE (n = 5,325) was matched by sex, year of birth, cancer type, and year of cancer diagnosis. Patients were followed until diagnosis of depression, emigration, death, study end (2021), or for a maximum of 3 years. Depression was defined as hospital discharge diagnosis of depression or ≥1 prescription for antidepressants. Absolute risks of depression were computed with cumulative incidence functions, treating death as competing event. Hazard ratios (HRs) with 95% confidence intervals (CIs) were computed using Cox proportional hazards regression models, adjusting for comorbidities.
Results Depression was observed in 158 hematological cancer patients with and 585 without VTE. The 3-year absolute risks of depression were 13.3% (95% CI: 11.5–15.3%) in the VTE cancer cohort and 11.1% (95% CI: 10.3–12.0%) in the comparison cancer cohort, corresponding to a risk difference of 2.2% (95% CI: -1.8–6.5%). VTE was associated with an increased relative risk of depression (adjusted HR: 1.56, 95% CI: 1.28–1.90).
Conclusion VTE was associated with an elevated risk of subsequent depression in patients with hematological cancer.
Assessment of pancreatic ductal stone density on non-contrast computed tomography for predicting the outcome of extracorporeal shock wave lithotripsy
Authors: Dalal Ankit , Kamat Nagesh , Maydeo Amit , Patil Gaurav , Vadgaonkar Amol , Parekh Sanil , Vora Sehajad 
Published: December 2023

Abstract
Background and study aims The utility of stone density at non-contrast computed tomography (NCCT) for predicting the effectiveness of extracorporeal shock wave lithotripsy (ESWL) in chronic calcific pancreatitis (CCP) is relatively unexplored.
Patients and methods This was a prospective observational study of patients with CCP. Hounsfield units (HU) were determined for the largest pancreatic ductal stone during pretreatment NCCT. All patients underwent ESWL until the largest stone was fragmented to <3mm, followed by endoscopic retrograde cholangiopancreatography (ERCP) for stone extraction. The predictive factors following ESWL for successful stone extraction were studied and the receiver operating characteristic (ROC) curve determined the HU optimal cut-point.
Results Eighty-two patients with a median (interquartile range) age of 36 years (range, 29–55); majority male 45 (54.9%), were included. Idiopathic CCP was noted in 78 patients (95.1%). The median stone density (SD) was 1095 HU (range, 860.7–1260.7) and the number of ESWL sessions was 2 (range, 2–3). Complete stone removal at index ERCP was achieved in 55 patients (67.1%). Those with partial clearance (n=27) needed a repeat ERCP, which was successful in 26 (96.3%); one patient (3.7%) underwent surgery. There was a significant, positive correlation between number of ESWL sessions and SD (r=0.797; P<0.001). On bivariate analysis, SD and the number of ESWL sessions revealed a significant association with complete ductal clearance. The optimal cut-point for complete stone removal by the ROC curve was 1106.5 HU (Youden index 0.726), with a sensitivity of 93% and a specificity of 80%.
Conclusions The SD is a significant predictor of ESWL success followed by ductal clearance at ERCP, and <1106.5 HU is a predictor of good candidates for ESWL therapy.
Nitro Compounds/Alcohols as Oxidant/Reductant Pairs: A Practical Synthesis of Azo Compounds and Ketones
Authors: Ma Renchao , Zhang Ruiqin , Ma Yongmin , Qiu Huanyi , Xie Jianhui 
Published: December 2023

AbstractHerein, a practical and green method for the synthesis of azobenzenes and ketones is reported using nitro compounds/alcohols as oxidant/reductant pairs under basic conditions. Alcohols and nitro compounds are oxidized/reduced in the absence of any metal catalysts under mild conditions and good yields of the corresponding ketones and azobenzenes are achieved selectively. In addition, the alcohols can even be oxidized with KNO3 or NaNO2.
Mesenchymal Stem Cells Applications in Alzheimer's Disease
Authors: Oyebode Oluwatosin Debola , Tulay Pınar 
Published: December 2023

AbstractAlzheimer's disease (AD) is a neurodegenerative disorder that advances gradually and primarily impacts the hippocampus region of the brain. It is defined by a deterioration in cognitive function as well as an observable loss of memory retention. One of the major characteristics of AD is the impairment of neural generation, resulting in the depletion of neurons and synaptic connections within the nervous system. It is unfortunate to say that, at present, no definitive cure is available for AD, and no medication is effective in halting the progression of neurodegeneration associated with it. Nevertheless, it is crucial to highlight that progress has been achieved in addressing the troubling symptoms of AD. The Food and Drug Administration has granted approval for two categories of medications designed to alleviate these symptoms. The scientific community has been inspired by these advancements to investigate alternative therapeutic options, with an emphasis on stem cell therapy in particular. The main focus of this review will be on the potential for the use of a variety of mesenchymal stem cells as a treatment for AD.
Effective resistance design and performance evaluation of energy conversion components
Authors: Chang Yingke , Chu Enyi , Ren Wei , Nie Jianxin , Li Hui , Zhao Wanjun , Guo Xiaorong 
Published: December 2023

The safety and reliability of the initiating explosive devices (IEDs) are critical for the weapon system. As the core components of IEDs, the method of resistance designing and the performance of conversion energy of energy conversion components (ECCs) are worth being studied. In this paper, the design method for the resistance of ECCs is established based on the finite element discrete method, and the currents of melting and electric explosion are presented for evaluating the performance of ECCs. The results show that the resistance of the ECCs is 1 ± 0.05 Ω with consistency. The ECCs were designed by the established design method of resistance and manufactured by the established machining method. The melting current of ECCs is 1.8 A, which is calculated by the infrared temperature measurement and finite element simulation. The electric explosion current of ECCs is 5 A, which was obtained by combining the snapshot obtained via the high-speed camera and finite element simulation.
Cryogenic optical packaging using photonic wire bonds
Authors: Lin Becky , Witt Donald , Young Jeff F. , Chrostowski Lukas 
Published: December 2023

The widespread adaptation of systems relying on optically controlled quantum information will require reliable and efficient multi-channel fiber-to-chip connections that function at cryogenic temperatures. Here we demonstrate low loss (2 dB per channel) connections between a single mode fiber array and tapered silicon waveguides down to 5 K using polymer based photonic wire bonds (PWBs). A method is described for assembling the silicon chip and fiber array such that the PWB connections are robust to temperature cycling and cryostat bakeout. The threshold power handling capability of the PWBs is greater than 4 dBm, sufficient to demonstrate optical bistability in silicon microring resonators coupled to the waveguides at 5 K.