bluuebunny/crossref_metadata_2025_split huggingface dataset:
Phytochemical analysis and antifungal efficiency of Origanum majorana extracts against some phytopathogenic fungi causing tomato damping-off diseases
Authors: Al-Otibi Fatimah , Alshahrani Reem A. , Alharbi Raedah I. , Yassin Mohamed Taha 
Published: January 2024

Abstract
Plant diseases represent one of the major problems causing yield loss of tomato crops, especially root rot and seedling damping-off diseases caused by some phytopathogenic fungi like Fusarium solani (Fs), F. oxysporum (Fo), and Macrophomina phaseolina (Mp) frequently detected in tomato either alone or in combination infection. The objective of the present study is to assess the antifungal activity of Origanum majorana extracts against the phytopathogenic fungi, Fs, Fo, and Mp, thereby avoiding controlling the disease with chemical fungicides. In this context, the acetonic extracts of O. majorana exhibited the highest antifungal activity against the tested phytopathogens. However, F. solani exhibited high resistance to Ridomil fungicide at the tested concentrations. A chemical analysis of the O. majorana acetonic extract was conducted to determine the main phytoactive constituents exhibiting fungicidal activity. In this regard, gas chromatography and mass spectrometry confirmed that 4-terpineol was the main phytoactive compound followed by γ-terpinolene exhibiting relative percentages of 24.36 and 8.26%, respectively. These results proved that the marjoram extract may contribute to the development of an alternative and natural fungicide to protect tomato crops from damping off and root rot diseases, avoiding the usage of chemical fungicides.
Study of photovoltaic integrated prefabricated components for assembled buildings based on sensing technology supported by solar energy
Authors: Liu Yuying , Zhang Hai , Chen Peng 
Published: January 2024

Abstract
In recent years, domestic and international policies to support energy-efficient buildings have been intensively introduced, and a consensus has been reached in the direction of green buildings. Building photovoltaic integration is a key technology to solve the demand for electricity in energy-efficient buildings. Meanwhile, prefabricated assembly house construction, as a common construction technology in the current building field, has the advantages of a short construction period, low project cost, a wide range of applications, and high structural stability. Green building and building industrialization are the direction of future construction industry development, combining building photovoltaic (PV) integration with assembly building, breaking down the whole structure into simple components in the factory standardization, batch production, and then on-site assembly, can reduce the mold cost, speed up the construction speed, and improve economic efficiency. The PV solar integrated assembled facade is in line with the concept of energy saving, low carbon, and environmental protection, with significant social benefits, which helps to promote rapidly in the market. In this article, by analyzing the performance and characteristics of PV modules, we propose the design method of PV-integrated prefabricated components for assembled buildings based on sensing technology, extract relevant design parameters from the database of building PV-integrated components, and test the feasibility of the modeling scheme in four stages of engineering design. The use of the results shows that the method of this article can target to improve the accuracy of PV-integrated prefabricated components, ensure the efficiency of component production and processing, and play an important role in supporting the widespread application of modern construction technology for building PV-integrated prefabricated assemblies.
Cohen’s Influence on Husserl’s Understanding of Kant’s Transcendental Method
Authors: Scagliusi Francesco 
Published: January 2024

Abstract
This article argues that Husserl’s interpretation of Kant’s “regressive method” was influenced by Cohen’s account of the “transcendental method.” According to Cohen’s epistemological reading of the Critique of Pure Reason, Kant’s transcendental method consists in explaining the “fact of science” by using a regressive procedure from this fact to its conditions of possibility. Husserl ascribes, as Cohen does, this method to Kant himself. First, he criticizes Kant for regressively deducing conditions of possibility that elude any type of intuitive fulfillment. Second, he understands Kant as a rationalist who wanted to advance intellectualism and oppose empiricism. Finally, Husserl holds that Kant’s concept of experience refers to scientific experience. All these points are central aspects of Cohen’s interpretation. Moreover, from Husserl’s own copy of Cohen’s Kant’s Theory of Experience we can observe that he had read §12 on Kant’s transcendental method. Therefore, there is a Cohenian influence on Husserl’s criticism of Kant’s method.
Self-assembled nanoscale entities: Preparative process optimization, payload release, and enhanced bioavailability of thymoquinone natural product
Authors: Akhtar Naseem , Ullah Zabih , Rashid Mohammad , Alshammari Abdulaziz Arif A. , Alshammari Anoud , Alawaji Razan , Khan Mohd Faiyaz , Al-Mutairi Abdulrahman , Khan Riaz A. 
Published: January 2024

Abstract
Thymoquinone (TMQ), present in Nigella sativa L., exhibits antioxidant, anti-inflammatory, and anti-apoptotic properties. Poor aqueous solubility, low oral bioavailability, hepatic first-pass metabolic constraints, and pH instability have limited TMQ’s in vivo use in clinical settings. This study designed and prepared thermodynamically stable, self-emulsified, nanoscale vesicles with the ternary diagram assistance to produce self-nanoemulsifying drug delivery system (SNEDDS). The TMQ-SNEDDS preparations used clove oil, isopropyl myristate (IPM) (1:1), Labrasol, and Transcutol-P. The SNEDDS mean droplet size varied between 72.85 and 98.42 nm, and approximately >70% TMQ was released within the first 4 h. The peak plasma concentration values of TMQSNE3 and TMQ suspension were 420.31 ± 35.23 and 98.51 ± 9.97 μg/mL, respectively, whereas time to achieve the peak plasma concentration values were 0.75 ± 0.12 and 1.0 ± 0.30 h, respectively. The area under the curve from time 0 to t (AUC0–t
) and the area under the moment curve from time 0 to t (AUMC0–t
) of TMQSNE3 were found to be 1838.63 ± 55.73 µg h/mL and 1909.59 ± 382.81 µg h/mL, respectively, which were highly significant (p < 0.05) in comparison with AUC0–t
(389.36 ± 87.08 μg h/mL) and AUMC0–t
(390.31 ± 184.55 μg h/mL) of the TMQ suspension. The relative bioavailability of TMQ was enhanced by 4.7-folds for the optimized TMQSNEDDS than that of the free drug suspension. The SNEDDS enhanced the bioavailability, which, in turn, positively affected the therapeutic efficacy of this naturally bioactive compound, TMQ, which has delivery and bioavailability problems owing to poor aqueous solubility.
Structure–mechanical property relationships of 3D-printed porous polydimethylsiloxane films
Authors: Zhu Xiaowei , Li Yue , Shi Yilun , Hou Lanjie , Wang Guoxian , He Zhoukun , Lan Xiaorong 
Published: January 2024

Abstract
Complex microstructures can be produced from different base materials by combining three-dimensional (3D) printing technology and ink formulations. The surface wettability of the 3D-printed porous polydimethylsiloxane (PDMS), particularly its superhydrophobic property, strongly depends on its physical structure. However, the mechanism underlying the effect of the microporous structure on the mechanical properties is not understood, which seriously constrains the structural–functional integration design of the 3D-printed superhydrophobic porous PDMS. To solve this problem, we studied the influence of the printing parameters on the mechanical properties in the compression and tension directions using a finite element method. The results showed that the load transfer path of the 3D-printed porous PDMS was along the overlapping area of the adjacent filaments. As the filament spacing decreased or the filament diameter increased, the elastic modulus of the porous PDMS was enhanced, improving its resistance to tensile and compressive deformation. A quantitative relationship was established between the relative densities of the porous PDMS films and their relative elastic moduli. This study provides theoretical guidance for the structural–functional integration design of 3D-printed superhydrophobic porous PDMS.
Die italienische Besatzungsherrschaft in Montenegro 1941 bis 1943
Authors: Goddi Federico 
Published: January 2024

Abstract
Ziel dieses Aufsatzes ist es, die Beziehungen zwischen dem italienischen Besatzungssystem und der montenegrinischen Gesellschaft während des Zweiten Weltkriegs zu rekonstruieren. Der italienische Faschismus priorisierte praxisorientierte Maßnahmen, die vor allem darauf abzielten, eine Neue Ordnung im Mittelmeerraum zu errichten. Exemplarische Einblicke in dieses repressive System liefert die Geschichte der italienischen Divisionen „Venezia“ und „Pusteria“. Die von diesen Großverbänden angewandten Strategien illustrieren den allgegenwärtigen Konflikt im italienischen Machtapparat. Daher untersucht Federico Goddi verschiedene Aspekte des Alltagslebens während der Besatzung und beleuchtet diese auch im Kontext der militärischen Repression und der ökonomischen Ausbeutung.
Lernende Polizei?
Authors: Mecking Sabine 
Published: January 2024

Abstract
Die Anti-Atomkraftbewegung gehörte zu den wichtigsten Protestbewegungen in der Bundesrepublik, sowohl aus gesellschaftlicher als auch aus polizeilicher Sicht. Obgleich die Neuen Sozialen Bewegungen im 20. Jahrhundert bereits intensiv erörtert wurden, sind dennoch Fragen zu den Interaktionen zwischen Protestierenden und Polizei sowie überhaupt zu den polizeilichen Reaktionen auf das gesellschaftliche Aufbegehren und den zum Teil damit einhergehenden Ausschreitungen offen. Die jüngere Gewaltsoziologie geht davon aus, dass der konkreten Situation eine hohe Relevanz zukommt. Entsprechend lenkt Sabine Mecking den Blick auf den spezifischen Protestraum und die Akteurinnen und Akteure vor Ort an den Bauplätzen der nuklearen Anlagen. Die vergleichende Analyse des polizeilichen Protestmanagements bei den Großdemonstrationen der Anti-Atomkraftbewegung in den 1970er und 1980er Jahren ist ein Beitrag zur Protest-, Gewalt- und Demokratiegeschichte der Bundesrepublik Deutschland.
Comparative Analysis of Schistosoma japonicum from Pairing-to-Sexual Maturation based on iTRAQ Proteomics
Authors: Yang Wen-Bin , Luo Fang , Zhang Rui-Xiang , Zhang Wei , Sun Cheng-Song , Wu-Yun Qi-Mu-Ge , Quan Jing-Wei , Luo Yang , Hu Wei 
Published: January 2024

Objective:
Schistosomiasis, which is caused by the schistosome worm, poses significant health challenges. Understanding the sexual development and maturation of schistosomes would provide valuable insight for preventing the transmission of schistosomiasis and pathologic damage to the host.

Methods:
Isobaric tags for relative and absolute quantitation (iTRAQ)-based proteomics was performed to monitor the dynamic proteomic profiles in Schistosoma japonicum during development from pairing-to-maturation. RNA interference (RNAi) experiments were used to elucidate sex-biased gene function.

Results:
Of the 2927 identified proteins, 58.6% showed differential expression after comparing sexes and developmental stages. Both male and female worms displayed a similar number of gender-differentially expressed proteins after pairing. However, these proteins exhibited significant gender-specific functions, with reproduction central in females, while males were enriched in metabolic processes. Females exhibited 73% of their time-variant protein expression during 22-26 days post-infection (dpi), while males had 62% during 18-22 dpi, indicating earlier maturation in males. Functional analysis revealed different peptidases expressed during male and female development and maturation. Sex-biased SjU2AF exhaustion led to worm development delay, abnormal reproductive organ development, and death.

Conclusions:
Comparative proteomics enhances our understanding of mechanisms underlying schistosome maturation and reveals a new potential target for chemotherapy and vaccines.
Evaluation of Tetracycline and Enrofloxacin Residues in Bovine Milk in Tehran Utilizing ELISA and HPLC Methods
Authors: Sohraby S. , Samakkhah S. Alian , Tooryan F. , Norian R. , Panahi Z. 
Published: January 2024

Background: Milk is regarded as one of the most sources of nutrition in the world and has a high value for individual's health. Milk is consumed by sensitive groups including pregnant women, older adults, and children. Therefore, the significance of antibiotic on human health makes it crucial to monitor their existence in food. This investigation aims to evaluate enrofloxacin and tetracycline in the raw and pasteurized milk in Tehran.
Methods: In this cross-sectional study, 112 raw and 112 pasteurized milks were accumulated in spring and winter from six reputable brands and traditional dairy stores in Tehran from December 2021 until May 2022 for six months, and antibiotic residues were examined by Immunosorbent Assay and High-Performance Liquid Chromatography techniques.
Results: The findings indicated that the prevalence of tetracycline in raw and pasteurized milk was 41.07 and 26.78% in spring and 85.71 and 35.71% in winter, respectively. The median concentration of tetracycline was 33.27 and 22.65 ppb in spring and 55.81 and 21.91 ppb in winter, respectively. The prevalence of enrofloxacin in raw milk and pasteurized milk samples were 33.92 and 14.28% in spring and 64.28 and 32.14% in winter, respectively. The median concentrations of enrofloxacin were 9.13 and 9.38 ppb in spring and 10.57 and 11.23 ppb in winter, respectively. The raw and pasteurized milk samples collected in winter had higher percentage of antibiotic residue in terms of enrofloxacin than samples collected in spring (p<0.05). Furthermore, the quantity of tetracycline antibiotic in raw milk was significantly higher in winter than in spring (p=0.002). However, the pasteurized milk fails to have significant difference between two seasons. The finding showed the tetracycline and enrofloxacin in all samples were less than 100 ppb (standard limit), and there is no significant difference with the standard limit.
Conclusion: Based on the obtained results, monitoring the antibiotic residues in milk, controlling and minimizing these residues for human health are regarded crucial.
Normospermic Patients Infected With Ureaplasma parvum: Role of Dysregulated miR-122-5p, miR-34c-5, and miR-141-3p
Authors: Galdiero Marilena , Trotta Carlo , Schettino Maria Teresa , Cirillo Luigi , Sasso Francesca Paola , Petrillo Francesco , Petrillo Arianna 
Published: January 2024

Background: Ureaplasma parvum (UP) is a causative agent of non-gonococcal urethritis, involved in the pathogenesis of prostatitis and epididymitis, and it could impair human fertility. Although UP infection is a frequent cause of male infertility the study evidence assessing their prevalence and the association in patients with infertility is still scarce. The molecular processes leading to defects in spermatozoa quality are not completely investigated. MicroRNAs (miRNAs) have been extensively reported as gene regulatory molecules on post-transcriptional levels involved in various biological processes such as gametogenesis, embryogenesis, and the quality of sperm, oocyte, and embryos.
Methods: Therefore, the study design was to demonstrate that miRNAs in body fluids like sperm could be utilized as non-invasive diagnostic biomarkers for pathological and physiological conditions such as infertility. A post-hoc bioinformatics analysis was carried out to predict the pathways modulated by the miRNAs dysregulated in the differently motile spermatozoa.
Results: Here it is shown that normospermic patients infected by UP had spermatozoa with increased quantity of superoxide anions, reduced expression of miR-122-5p, miR-34c-5, and increased miR-141-3p compared with non-infected normospermic patients. This corresponded to a reduction of sperm motility in normospermic infected patients compared with normospermic non-infected ones. A target gene prediction presumed that an essential role of these miRNAs resided in the regulation of lipid kinase activity, accounting for the changes in the constitution of spermatozoa membrane lipids caused by UP.
Conclusions: Altogether, the data underline the influence of UP on epigenetic mechanisms regulating spermatozoa motility.
The visual arts' role in the development of students' noosphere worldview
Authors: Nurke Maira , Zhumabayeva Aziya , Adenova Lyazzat , Baikenova Shaizada , Abilkalamova Kamilya 
Published: January 2024

Noospheric education is considered the basis for the formation of an environmental culture in people and society aimed at solving a complex of problems related to ensuring the sustainable development of society. Identifying promising areas for noospheric education development and demonstrating the importance of students developing a noospheric vision of the world through the visual arts depend on whether the necessary conditions for achieving the desired results have been established. This study aims to examine the impact of software on the effective formation of students' noospheric vision of the world using the visual arts. A quantitative and qualitative research design was used in this study. The study involved 240 fourth-grade students at secondary school no. 12 in the city of Almaty (Kazakhstan). The findings revealed issues with the formation of students' noospheric worldviews which demonstrates that students have an unstable perception of the intellectual sphere and develop an enthusiasm for the bright, spectacular objects and phenomena of their surroundings rather than their content. Experts can use the research findings to model environmental education in secondary schools, in the practical work of visual arts instructors, in the creation of curriculum and instructional aids for the visual arts and in the transmission of information on noospheric concepts.
Pemanfaatan Data Hujan Satelit Untuk Pembuatan Peta Spasial Hujan Rancangan Di DAS Kedunggaleng
Authors: Putri Wanda Pratiwi Putri , Harisuseno Donny Harisuseno , Wahyuni Sri Wahyuni 
Published: January 2024

Bencana banjir pada Daerah Aliran Sungai (DAS) Kedunggaleng terjadi karena adanya luapan pada aliran sungai. Upaya mitigasi banjir memerlukan data masukan hujan yang akurat dari aspek panjang data hujan dan sebaran kejadian hujan (spatial) yang di DAS Kedunggaleng. Keberadaan data hujan satelit menjadi alternatif untuk memperkirakan data hujan pada bagian DAS yang tidak terukur. Studi ini bertujuan untuk menghasilkan perkiraan peta spasial hujan rancangan berbagai kala ulang dengan teknik interpolasi spasial Inverse Distance Weight (IDW) dengan memanfaatkan data hujan satelit CHIRPS dan data hujan pengamatan. Kalibrasi data hujan satelit dengan pengamatan dilakukan untuk mencari persamaan hubungan keduanya. Kala ulang hujan rancangan yang digunakan meliputi 2, 5, 10, 25, 50 dan 100 tahun. Distribusi frekuensi Gumbel dan Log Pearson III digunakan untuk menghitung hujan rancangan, yang selanjutnya digunakan sebagai data masukan pembuatan peta sebaran hujan dengan interpolasi IDW. Peta hujan rancangan hasil interpolasi IDW dibandingkan dengan hujan rancangan hasil analisis frekuensi dan dari peta hujan rancangan Kementerian PUPR dimana penilaian dilakukan dengan kriteria Root Mean Standard Ratio (RSR) dan Nash Sutcliffe Efficiency (NSE). Hasil validasi hujan rancangan dari interpolasi IDW menunjukkan performa yang baik dimana hasil perbandingan dengan peta hujan rancangan Kementerian PU menunjukkan nilai Kesalahan relatif (KR) sebesar 5,94%.
Identifying Factors of User Acceptance of a Drone-Based Medication Delivery: User-Centered Design Approach
Authors: Fink Franziska , Kalter Ivonne , Steindorff Jenny-Victoria , Helmbold Hans Konrad , Paulicke Denny , Jahn Patrick 
Published: January 2024

Background
The use of drones in the health care sector is increasingly being discussed against the background of the aging population and the growing shortage of skilled workers. In particular, the use of drones to provide medication in rural areas could bring advantages for the care of people with and without a need for care. However, there are hardly any data available that focus on the interaction between humans and drones.

Objective
This study aims to disclose and analyze factors associated with user acceptance of drone-based medication delivery to derive practice-relevant guidance points for participatory technology development (for apps and drones).

Methods
A controlled mixed methods study was conducted that supports the technical development process of an app design for drone-assisted drug delivery based on a participatory research design. For the quantitative analysis, established and standardized survey instruments to capture technology acceptance, such as the System Usability Scale; Technology Usage Inventory (TUI); and the Motivation, Engagement, and Thriving in User Experience model, were used. To avoid possible biasing effects from a continuous user development (eg, response shifts and learning effects), an ad hoc group was formed at each of the 3 iterative development steps and was subsequently compared with the consisting core group, which went through all 3 iterations.

Results
The study found a positive correlation between the usability of a pharmacy drone app and participants’ willingness to use it (r=0.833). Participants’ perception of usefulness positively influenced their willingness to use the app (r=0.487; TUI). Skepticism had a negative impact on perceived usability and willingness to use it (r=−0.542; System Usability Scale and r=−0.446; TUI). The study found that usefulness, skepticism, and curiosity explained most of the intention to use the app (F3,17=21.12; P<.001; R2=0.788; adjusted R2=0.751). The core group showed higher ratings on the intention to use the pharmacy drone app than the ad hoc groups. Results of the 2-tailed t tests showed a higher rating on usability for the third iteration of the core group compared with the first iteration.

Conclusions
With the help of the participatory design, important aspects of acceptance could be revealed by the people involved in relation to drone-assisted drug delivery. For example, the length of time spent using the technology is an important factor for the intention to use the app. Technology-specific factors such as user-friendliness or curiosity are directly related to the use acceptance of the drone app. Results of this study showed that the more participants perceived their own competence in handling the app, the more they were willing to use the technology and the more they rated the app as usable.
أهمية تطوير طرائق تدريس اللغة العربية لأغراض أكاديمية
Authors: Zannrni Imadin M. , Al-Faris Suhair S. 
Published: January 2024

يحاول البحث الحالي الموجز أن يعرّف طرائق تدريس اللغة العربية لأغراض أكاديمية AAPعلى أنها أحد مكونات المنهج الجامعي العراقي، وأن يبين أهميتها في الارتقاء بتدريس اللغة العربية لأغراض أكاديمية، ويقف على واقعها في الجامعات العراقية، وأن ترسم بعض المسارات للنهوض بواقع برامج الترجمة في الجامعات العراقية. يستخدم البحث طريقة الملاحظة الموضوعية الوصفية لوصف التعليم العالي للغة العربية لأغراض أكاديمية في العراق. وتبرز طرائق تدريس اللغة العربية لأغراض أكاديمية كأحد أهم مكونات مناهج اللغة العربية لأغراض أكاديمية في التعليم العالي في العراق، إذ كان منهج اللغة العربية لأغراض أكاديمية قديماً مرادفاً للمقررات الدراسية ومقتصراً عليها ويرمي إلى تزويد المتعلمين بالمعارف والمعلومات دون الأخذ بالحسبان جوانب الشخصية الأخرى، وإنما كانت العناية فيه تقتصر على الناحية العقلية من نمو المتعلم، حتى إنه لم يكن يعنى بإنماء النواحي العقلية ذات الدلالة في مجتمعنا المعاصر كتنمية التفكير الابتكاري وإهمال الدوافع الموجهة للسلوك. أما المنهج حالياً فهو يتضمن جميع الخبرات التي تقدمها الجامعة إلى طلابها تحقيقاً لرسالتها الكبرى في بناء البشر وفق أهداف تربوية محددة، بما يساعد على تحقيق نموهم الشامل جسمياً وعقلياً ونفسياً وجمالياً وروحياً واجتماعياً وإنسانياً.