bluuebunny/crossref_metadata_2025_split huggingface dataset:
The effect of temperature on the mechanical behavior of Berea sandstone under confining pressure: experiments
Authors: Iftikhar Ch Mohammad Abbas , Khan Akhtar S. , Nambori Venkata 
Published: November 2023

AbstractFor the first time, axial and circumferential (diametral) strains are measured directly on Berea sandstone cylindrical samples at different high temperatures as a function of confining pressure. The maximum compressive principal stress was in the direction perpendicular to the bedding plane. Tri-axial compression tests have been conducted under confining pressures ranging from atmospheric pressure to 12,000 psi “82.73 MPa” (gage), and the temperature was varied from room temperature (RT) to 250°F (121.11 °C). In all the experiments, specimens are dry, and no pore pressure is applied. Uniaxial axial force (100 lbs/min or 444.82 N/min) and strains in the three directions ($$\varepsilon$$
ε
1, $$\varepsilon$$
ε
2, $$\varepsilon$$
ε
3) is directly measured from the strain gages mounted on the specimen; hence the study reflects the behavior of the Berea sandstone up to the initiation of the failure only. The experimental observations involving yield, failure, transition from brittle to ductile behavior, and their dependence on temperature and confining pressure are presented. Parameters like ductility and dilatancy (reflecting volumetric behavior before failure) and their variation with temperature and confining pressure are given. The initial yield and failure of Berea sandstone are presented in terms of the generalized von-Mises criteria, i.e., variation of octahedral shear stress ("Image missing") with the mean stress. The loads at yield and failure are found to decrease with increasing temperature and augment with increasing confining pressure. The ductility and dilatancy reduction are computed using measured strains with increasing temperature. With an increase in temperature, the volume decreases first, partly due to the initial closure of micro cracks and voids, then increases due to generation of additional microcracks and voids (damage). There is less volume decrease in the uniaxial test response at higher temperature as compared to the corresponding ambient temperature response. A monotonic increase in the octahedral shear stress at yield and failure is observed with increasing confining pressure.
Ferrite shielding thickness and its effect on electromagnetic parameters in wireless power transfer for electric vehicles (EVs)
Authors: Yadav Ankur , Bera Tushar Kanti 
Published: November 2023

AbstractWireless power transfer (WPT) has become an increasingly popular technology for charging electronic devices wirelessly. One of the key challenges in WPT is increasing efficiency and reducing different losses in coils caused by the higher air gap and coil coupling between the primary and secondary coils. Ferrite shielding is a common technique used to reduce losses and increase the coupling in WPT systems. In this paper, we present an analysis and comparison study of the effect of ferrite shielding thickness ($$F_T$$

F
T

) on the electromagnetic parameters of WPT systems. We investigate the impact of varying the ferrite shielding thickness on parameters such as power transfer efficiency, coupling coefficient (k), and magnetic field strength (B). Our results show that increasing the ferrite shielding thickness can significantly reduce losses and improve the performance of WPT systems. Also, analyze the trade-off between ferrite shielding thickness and power transfer efficiency and provide guidelines for selecting an optimal thickness for a given application. This study provides valuable insights into the design and optimization with weight vs. coupling comparison for WPT systems using ferrite shielding. It can help inform the development of future WPT technologies. The result obtained through simulation, i.e., coil-to-coil efficiency, is 98.88 to 99.7360% at 6.78MHz frequency for a 5-mm- to 50-mm-thick ferrite rectangular coupler using ANSYS Maxwell and ANSYS simplorer software.
Imaginary of Behavioral Governing
Authors: Małecka Magdalena 
Published: November 2023

AbstractThe article introduces the concept of the imaginary of behavioral governing to capture the view on the role of behavioral research in governing behavior that is widely shared in the academic and public discussions about behavioral policy (nudging), including the recent debates about reliance on big data and algorithms to influence people's behavior. It is believed that behavioral science provides knowledge of stable regularities of behavior and of the cognitive processes that lead to them, and that policymakers/governments act upon this knowledge to change behavior of individuals. I argue that this set of claims about the knowledge provided by the behavioral sciences is not substantiated in behavioral research. The formal theoretical frameworks of behavioral science come to be interpreted — via the imaginary of behavioral governing — as relating to human agents that power can act upon. I reflect on the possible point of entry for critique of this imaginary and its effects.
The Contest between Information and Uncertainty
Authors: Rohde Joy 
Published: November 2023

AbstractThis article argues that the Cold War – era battle between information and uncertainty is a critical origin point for contemporary social theory – informed, data-intensive projects of the US national security state. Beginning in the 1950s, international relations experts and government officials turned to digital computing to help make decisions under the unavoidable pressures of geopolitical uncertainty. By the 1970s, their data banks of political knowledge and novel statistical tools purported to forecast political unrest long before an unaided human could. These efforts sparked a new epistemology of political knowledge, one that is now common in data science, in which designers and users prioritize correlation over causality and the instrumental management of problems over scholarly understanding or explanation. Far from a historical curiosity, this history is a warning. The sensibilities of Cold War technopolitical projects are continually rematerialized in contemporary computational security projects. Left unchallenged, their durability will continue to increase in tandem with the national security state's continued investment in computational social scientific projects for geopolitical management.
A 3-Year Survival Update from a Phase 2 Study of Paclitaxel Plus Cisplatin and 5-Fuorouracil Induction Chemotherapy for Locally Advanced Borderline-Resectable Esophageal Squamous Cell Carcinoma: The NEOCRTEC-1601 Clinical Trial
Authors: Wu Jia-Di , Wang Zhi-Qiang , Li Qiao-Qiao , Li Zhi-Chao , Ren Chao , Wang De-Shen , Chen Ji-Yang , Tan Qiong , Li Yu-Hong , Yang Hong 
Published: November 2023

Abstract
Background
This study updated 3-year analyses to further characterize the impact of docetaxel, cisplatin, and fluorouracil (TPF) chemotherapy followed by surgery.

Methods
This study was a single-center phase 2 clinical trial. Patients with a diagnosis of borderline resectable esophageal squamous cell carcinoma (BR-ESCC) because of the primary tumor or bulky lymph node that potentially invaded adjacent organs were eligible. The treatment started with TPF chemotherapy followed by surgery if the cancer was resectable, or by concurrent chemoradiation if it was unresectable. This updated report presents the 3-year overall survival (OS) and progression-free survival (PFS) rates.

Results
Surgery was performed for 27 patients (57.4%), and R0 resection was confirmed in 25 patients (53.2%). Pathologic complete response was confirmed in four patients (8.5%). The median follow-up time for the surviving patients was 44.8 months (range, 3.4–74.6 months). The median OS for all the patients was 41.9 months (95% confidence interval [CI], 18.6–65.3 months), with a median PFS of 38.7 months (95% CI, 23.5–53.9 months). The 3-year survival rate for all the patients was 54.4%. The 3-year survival rate for the R0 patients was 65.4%.

Conclusion
Long-term follow-up evaluation confirmed that TPF followed by surgery is feasible and promising in terms of survival for BR-ESCC patients.
Trial Registration ClinicalTrials.gov identifer: NCT02976909.
Synthesis, characterization, and evaluation of nanoparticles of clodinofop propargyl and fenoxaprop-P-ethyl on weed control, growth, and yield of wheat (Triticum aestivum L.)
Authors: Khan Bilal Ahmad , Nadeem Muhammad Ather , Najeed Alawadi Hussam F. , Javaid Muhammad Mansoor , Mahmood Athar , Qamar Rafi , Iqbal Mudassar , Mumtaz Amina , Maqbool Rizwan , Oraby Hesham , Elnaggar Nehal 
Published: November 2023

Abstract
Nanoherbicides are articulated by exploiting the prospective of nanotechnology for effectively delivering chemical and biological herbicides using nanomaterial‐based herbicide combinations. The nanoparticles were characterized using X-ray diffraction and FT-IR. On the targeted weeds, the nanoherbicides were sprayed at the third to fourth leaf stage. Six different doses were applied. The mortality and visual injury caused by both chitosan-based nanoherbicides reached 100% at the recommended dose of standard herbicide. The 5-fold lower dose exhibited weed density and maximum wheat yield and related parameters. For the same traits, the nanoherbicide at 10-fold lower dose of commercial herbicides showed a comparable influence as the suggested dose. The size of both herbicides was found to be 35–65 nm. It was observed that the clodinofop-propargyl nanoherbicide has an intense peak appearing at a 2θ value of 29.83°, corresponding to the (176) plane of the anatase phase and NPs of fenoxaprop-P-ethyl showed an intense peak around the 2θ value of 30.55° corresponding to the (74) plane of the anatase phase. The FT-IR spectra of fenoxaprop-P-ethyl clearly showed that the major functional groups were located in the FT-IR region between 610 and 1,840 cm−1 and the major functional ones of clodinofop propargyl were located in the FT-IR region between 640 and 1,740 cm−1. Nanoherbicides could restore the efficacy of conventional herbicides by improving stability and reducing toxicity.
CircMMP11 as a prognostic biomarker mediates miR-361-3p/HMGB1 axis to accelerate malignant progression of hepatocellular carcinoma
Authors: Zou Qiong , Zhang Yuping , Zhu Daoqi , Liu Xinrong , Wang Changfa , Xiang Hong 
Published: November 2023

Abstract
As a high metastatic tumor, patients having hepatocellular carcinoma (HCC) show poor prognosis. The carcinogenic roles of circMMP11 are generally described in the development of other cancers. However, there is a lack of studies on its involvement in HCC. Therefore, we investigated the potential role and molecular mechanisms of CircMMP11 in the development of HCC in vitro, providing preliminary evidence for the clinical treatment of HCC. First, we examined the expression of CircMMP11 in HCC tissues and cell lines in both clinical and in vitro experiments. We then used a loss-of-function assay to determine CircMMP11’s regulatory role on the malignant characteristics of HCC cells. The results showed that high expression of CircMMP11 in HCC was associated with patient overall survival. Serum CircMMP11 had good diagnostic efficacy in distinguishing HCC patients from the control group. In vitro, inhibiting CircMMP11 suppressed the malignant characteristics of human HCC cell lines by directly sequestering miR-361-3p, which further affected the downstream gene HMGB1 expression. In addition, we knocked down CircMMP11 and found that its deletion inhibited the malignant characteristics of HCC cells through the miR-361-3p/HMGB1 axis.
Crystal structure of [triaqua-(8-carboxymethoxy-quinoline-2-carboxylate-κ
4
N,O,O,O)cadmium(II)]monohydrate, C12H15NO9Cd
Authors: Li-Hua Wang , Xi-Hai Yan , Yuan-Fang Wang , Xi-Shi Tai 
Published: November 2023

Abstract
C12H15NO9Cd, triclinic,

P

1
‾

$P\overline{1}$

(no. 2), a = 7.5263(5) Å, b = 8.0953(3) Å, c = 12.4005(8) Å, α = 86.814(4)°, β = 79.845(5)°, γ = 86.140(4)°, V = 741.28(7) Å3, Z = 2, R

gt
(F) = 0.0759, wR

ref
(F
2) = 0.2248, T = 295 K.
Forceful patterning: theoretical principles of mechanochemical pattern formation
Authors: Rombouts Jan , Elliott Jenna , Erzberger Anna 
Published: November 2023

AbstractBiological pattern formation is essential for generating and maintaining spatial structures from the scale of a single cell to tissues and even collections of organisms. Besides biochemical interactions, there is an important role for mechanical and geometrical features in the generation of patterns. We review the theoretical principles underlying different types of mechanochemical pattern formation across spatial scales and levels of biological organization.
Determination of anti-microbial and anti-viral efficacy of the mixture of extracted piper betle linn leaves and cynodon dactylon with curd and calcium oxide against shingles disease
Authors: Shaikh Afroj Ayyaj , Shejul Dhanashri D. , Shekade Mahesh P. , Anbhule Sachin J 
Published: November 2023

The prevalence of shingles disease has become a significant concern in the healthcare industry, and the search for effective treatment options has intensified. In this research paper, we investigate the anti-microbial and anti-viral efficacy of a mixture of extracted Piper Betle Linn leaves and Cynodon Dactylon with curd and calcium oxide against shingles disease. The study employed a randomized controlled trial design, with participants divided into four groups. The first group was administered the mixture of extracted Piper Betle Linn leaves and Cynodon Dactylon, the second group received the same mixture with curd, the third group was given the mixture with calcium oxide, while the fourth group served as the control and received a placebo. Results from the study revealed that the mixture of extracted Piper Betle Linn leaves and Cynodon Dactylon with curd and calcium oxide demonstrated potent anti-microbial and anti-viral efficacy against shingles disease, as evidenced by a significant reduction in the severity and duration of symptoms. The mixture was also found to be safe and well-tolerated by participants, with no adverse effects reported.The findings of this research paper have significant implications for the treatment of shingles disease, as the mixture of extracted Piper Betle Linn leaves and Cynodon Dactylon with curd and calcium oxide presents a promising alternative to conventional treatment options. The use of natural extracts and compounds in the mixture also provides a safer and more sustainable approach to treating the disease. In conclusion, the results of this study demonstrate the effectiveness of the mixture of extracted Piper Betle Linn leaves and Cynodon Dactylon with curd and calcium oxide in treating shingles disease. Further research is needed to fully explore the potential of this mixture in combating other viral and microbial infections.
The Management of Acute Ischaemic Stroke – A Review and South African Perspective
Authors: Sadiq Eitzaz , Kroon Louis , Brey Naeem , Mochan Andre 
Published: November 2023

AbstractReperfusion therapy in acute ischaemic stroke, namely intravenous thrombolysis and mechanical thrombectomy, have traditionally had strict time-based eligibility criteria. Recent advances in diagnostic and imaging modalities have resulted in a more dynamic view of eligibility for these therapies. The time clock concept may soon be superseded by the “tissue clock” concept, where accurate identification of the extent of the salvageable penumbra has been shown to result in favourable outcomes well beyond the traditional time limits in carefully selected patients. However in a low-middle income country like South Africa, the social, economic and geographic barriers to an effective acute stroke management service are often overwhelming. In this review we provide an update on the current evidence guiding management of acute ischaemic stroke, with a particular emphasis on the challenges faced in resource-constrained regions.
THE REGULATORY IMPROVEMENT OF INSURANCE LAW REFORM IN ORDER TO PURSUE THE LEGAL CERTAINTY FOR THE PEOPLE AND THE INSURANCE COMPANY
Authors: Wijanto Wihadi 
Published: November 2023

<p><em>The growth of insurance sector in Indonesia so far shows a significant development. The data from the Financial Services Authority (OJK) recorded that in 2020 there were 139 insurance companies had obtained the permits to run their business in Indonesia. <em>This number has been decreasing over the past five years due to the failure of several big insurance companies in managing the customer's insurance premium. For example, Bakrie Life and Bumi Asih Jaya Insurance. The research methods on this dissertation are normative with an empirical support to verify the basic research problem and to regulate an ideal formulation of legal protection for all insurance policyholders against the intentional mismanagement by the insurance companies. The results show that until now the rights of all insurance policyholders are still referring to the Commercial Law ( Trade Law Book ) and the Insurance Law. Both regulations do not specifically regulate the rights of insurance policyholders, especially those related to the investments or funds in the non-state-owned (non-BUMN) insurance companies with the priority of refunding if there is an intentional mismanagement or criminal acts committed by the director of the insurance company. The research concluded that the existing regulations do not provide a legal certainty for the insurance policyholders to get refunds for their deposit funds. This means, there is no legal protection for the insurance policyholders when the above mentioned crime occurs or when a violation occurs, or when there is a reinvestment failure. Therefore, it is recommended that the insurance law regulatory improvements be carried out, specifically those related to: </em><em>1) Non-litigation settlement mechanisms such as Arbitration (BANI), 2) Litigation settlement mechanisms including private law suit, force majeure, illegal act, bankruptcy suit against the investment managers, or criminal charges for embezzlement, fraud, or money laundering. In addition, it is necessary to have improvements of the technical provisions POJK No. 06/POJK.07/2022 concerning Consumer and Public Protection in the Financial Services Sector.</em></em></p><p><em> </em></p><p><em>Key Words: Legal Certainty; Customer Funds; The Failure of Reinvestment</em></p>
Treatment of Depression With Psychotic Features in Maltreated Adolescents: Evidence-Based Case Report
Authors: Setiawan Feronia Augustine , Phernando Nicholas Kevin , Ulya Zuhrotun 
Published: November 2023

Introductions: Depressive disorders are expected consequences of experiencing child maltreatment. Many depressive disorders can occur with or without psychosis, which has different implications for treatment and prognosis. This condition raises the challenge of treating depression in maltreated adolescents because the patient has inadequate family and social support. Consequently, it is difficult for the patient to undergo psychotherapy that involves family. Case: A 17-year-old female was diagnosed with psychotic depression. The patient had symptoms of depression, accompanied by hallucinations, since five years ago. The patient was hospitalized for suicidal ideation and food refusal for days. Patient had a history of child maltreatment by family and experienced bullying since elementary school. Patient believes that her family, especially her mother, had hated her from the beginning. Discussions: After stabilization of the patient’s general condition, psychopathology exploration was done together with selection of appropriate treatment. Combined Cognitive Behavioral Therapy (CBT), Selective Serotonin Reuptake Inhibitor (SSRI) and atypical antipsychotic treatment are the evidence-based treatments for psychotic depression in maltreated adolescents. Studies involving patients with psychotic depression which were treated by combination of sertraline and olanzapine showed significant improvement of depression and psychotic symptoms and reduced the risk of relapse over 36 weeks, compared to sertraline plus placebo. Conclusion: Combination of SSRI, atypical antipsychotic and CBT with a trauma-informed approach should be considered as treatment for psychotic depression in maltreated adolescents.
Educator as the Key for Digital Transformation in Curriculum and Learning
Authors: Pratiwi Mega Cahya , Riyana Cepi 
Published: November 2023

<p>Era disrupsi ditandai dengan adanya VUCA (Volatility, Uncertainty, Complexity, Ambiguity) dimana masyarakat dihadapkan pada perubahan yang sulit diprediksi, ketidakpastian, kompleksitas, serta ambiguitas yang terjadi di hampir semua aspek kehidupan, tidak terkecuali pendidikan. Transformasi digital dalam bidang pendidikan menjadi sebuah keniscayaan, karena transformasi digital adalah tentang bagaimana perusahaan atau organisasi beradaptasi dengan realitas baru. Dalam hal tersebut, pendidik menjadi salah satu aspek yang terlibat dalam upaya transformasi digital dalam kurikulum dan pembelajaran. Oleh karena itu, penelitian ini bertujuan untuk menunjukkan bahwa pendidik merupakan kunci keberhasilan upaya transformasi digital dalam kurikulum dan pembelajaran serta untuk mengetahui bagaimana agar pendidik siap dalam mendukungnya. Untuk mengupayakan keberhasilan suatu organisasi atau institusi pendidikan dalam melakukan transformasi digital dimulai dengan perubahan <em>mindset </em>(pola pikir), memilih <em>toolset</em> (teknologi), terakhir melatih <em>skill set</em> (keterampilan). Pendidik perlu dilatih agar menjadi pribadi yang <em>growth mindset </em> dengan dapat melihat dirinya sebagai orang yang terus berubah dan selalu ingin tahu tentang berbagai topik sehingga mereka selalu memiliki kesiapan menghadapi berbagai perubahan yang ada.</p>
Antifungal Susceptibility Pattern of Candida species Isolated from Pregnant Women in ‎Hajjah Governorate, Yemen
Authors: Xue Gao , Ali Maqsood , Edrees Wadhah Hassan , Al-Shehari Wadee , Chaulagain Ram Prasad , Lal Nand , Al-Hammadi Safa , Qasem Eglal Ahmed 
Published: November 2023

Abstract

Background and Aims: Candida
species, opportunistic yeast, are the second most common cause of female vulvovaginal candidiasis. This study aimed to evaluate the antifungal susceptibility profile of the isolated Candida species in pregnant women in Hajjah governorate, Yemen. Materials and Methods: A hospital-based cross-sectional study was conducted among 396 pregnant women attending Authority AL-Gumhorri Hospital Hajjah between February and July 2023. Vaginal swabs were collected, and Candida species were isolated and identified based on the standard laboratory method. Furthermore, the antifungal drug susceptibility of Candida species was determined by the Kirby-Bauer technique. Results: The prevalence of vaginal Candida infection among pregnant women was 61.4%. Candida albicans was the most predominant species (59.26%), followed by C. krusei (13.58%), C. tropicalis (11.12%), C. glabrata (9.87%), and C. dublinensis (6.17%). The highest rate of Candida infections was among women aged 24–30 years (71.9%) who finished primary school (77.8%), with the third trimester (80%), multigravida (66.1%), and recurrent infection (67.7%) showing significant differences (P ˂ 0.05). The C. albicans isolates were resistant to clotrimazole and itraconazole at 34.7% and 23.6%, respectively. In addition, the resistance of C. krusei, C. tropicalis, C. glabrata, and C. dublinensis isolates to fluconazole, voriconazole, voriconazole, and nystatin was 57.6%, 63%, 43.8%, and 60%, respectively. Additionally, approximately 46.2% of isolated Candida albicans exhibited one kind of antifungal drug resistance, whereas 38.7% of isolated non-albicans exhibited resistance to three different antifungal agents. Conclusion: According to the above findings, Candida infection is highly prevalent in Yemen and quite widespread. Interventions in health education are advised to increase women's knowledge of vaginitis and its prevention. The antifungal susceptibility test may also be helpful in determining the best medication for each patient.