bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultrasensitive Room Temperature Infrared Photodetection Using a Narrow Bandgap Conjugated Polymer
Authors: Liu Chih‐Ting , Vella Jarrett , Eedugurala Naresh , Mahalingavelar Paramasivam , Bills Tyler , Salcido‐Santacruz Bernardo , Sfeir Matthew Y. , Azoulay Jason D. 
Published: October 2023

AbstractPhotodetectors operating across the short‐, mid‐, and long‐wave infrared (SWIR–LWIR, λ = 1–14 µm) underpin modern science, technology, and society in profound ways. Narrow bandgap semiconductors that form the basis for these devices require complex manufacturing, high costs, cooling, and lack compatibility with silicon electronics, attributes that remain prohibitive for their widespread usage and the development of emerging technologies. Here, a photoconductive detector, fabricated using a solution‐processed narrow bandgap conjugated polymer is demonstrated that enables charge carrier generation in the infrared and ultrasensitive SWIR–LWIR photodetection at room temperature. Devices demonstrate an ultralow electronic noise that enables outstanding performance from a simple, monolithic device enabling a high detectivity (D*, the figure of merit for detector sensitivity) >2.44 × 109 Jones (cm Hz1/2 W−1) using the ultralow flux of a blackbody that mirrors the background emission of objects. These attributes, ease of fabrication, low dark current characteristics, and highly sensitive operation overcome major limitations inherent within modern narrow–bandgap semiconductors, demonstrate practical utility, and suggest that uncooled detectivities superior to many inorganic devices can be achieved at high operating temperatures.
Computational Investigation of MAX as Intercalation Host for Rechargeable Aluminum‐Ion Battery
Authors: Wang Lin , Wang Jingyang , Ouyang Bin 
Published: October 2023

AbstractLayered carbides and their analogs with MAX phase (general formula AMn+1Xn) have emerged as promising candidates for energy storage and conversion applications. One frontier for energy storage is using MAX as an Al‐ion intercalation electrode. Given that many MAXs have Al as the A sites, the structure can potentially serve as a stable host for Al intercalation. Here in this work, 425 ternary MAX Al‐ion battery electrodes are computationally enumerated. Specifically, first principal phase diagram calculations are performed on the combinatorial space of 17 types of typical transition metals, five types of anions (C, N, B, Si, and P), three types of stoichiometries (n = 1, 2, and 3) and two types of layered stackings (α and β). Among all the ternary MAX materials, 44 candidates show reasonable synthetic accessibility, and six with extraordinary performance are predicted to be promising Al‐ion battery electrodes. With the phase stability, and electrochemical performance (average voltage, theoretical capacity, energy density, and Al diffusion barrier), the work provides a comprehensive computational assessment of the great opportunities behind MAX‐based Al‐ion batteries.
Inoculant and fertilizer effects on lentil in the US northern Great Plains
Authors: Miller P. R. , Atencio S. C. , Jones C. A. , Carr P. M. , Eriksmoen E. , Franck W. , Rickertsen J. , Fordyce S. I. , Ostlie M. , Lamb P. F. , Fonseka D. L. , Grusak M. A. , Chen C. , Bourgault M. , Koeshall S. T. , Baber K. W. 
Published: October 2023

AbstractLentil (Lens culinaris Medikus) is an important crop, averaging over 250,000 ha in Montana and North Dakota during 2016–2021. However, relatively little is known about rhizobial inoculant and fertility response in lentil in the US northern Great Plains. The objective was to evaluate the effect of rhizobial inoculant formulations (seed coat and in‐furrow) and nutrient additions (potassium [K], sulfur [S], and micronutrients) on lentil yield and seed protein concentration. This study was conducted at seven university research centers in Montana and North Dakota from 2019 to 2021, resulting in 20 location‐years of data. In six of 20 experiments, inoculant application increased seed yield by an average of 36% (323 kg ha−1, p ≤ 0.05) but had no consistent effect on seed protein concentration. Lentil or pea crop history among locations did not explain inoculant response. Inoculant formulations (seed coat vs. in‐furrow) and K fertilizer had inconsistent and small effects on seed yield and protein concentration. However, S fertilizer (5.6 kg S ha−1) increased seed yield in four of 20 experiments (p ≤ 0.02) by an average of 14.5% (255 kg ha−1) in those experiments and decreased seed yield for one experiment (p = 0.05) by 5.8% (153 kg ha−1). Pre‐plant SO4‐S soil test levels did not predict lentil response to S fertilizer. Micronutrient application was assessed in 12 location‐years but had no effect on lentil yield or protein concentration. This research suggests a need to better understand what factors control lentil yield and protein response to rhizobial inoculant and S fertilization.
Associations of maternal stress, gene expression, and newborn birthweight in the Democratic Republic of Congo
Authors: Hsiao Chu J. , Quinn Edward B. , Maisha Felicien M. , Nevell Lisa D. , Mulligan Connie J. 
Published: October 2023

AbstractObjectivesMaternal stress has long been associated with lower birthweight, which is associated with adverse health outcomes including many adult diseases. The underlying mechanisms remain elusive although changes in gene expression may play a role. Studies are only beginning to test how maternal stress impacts gene expression as reflected in the transcriptome.Materials and MethodsIn a cohort of mothers and newborns in the eastern Democratic Republic of Congo (n = 93), we studied the effects of four maternal stress measures (chronic stress, war trauma, sexual trauma, and general trauma) on the transcriptomes of maternal venous blood, newborn venous blood, and placental tissues, and on newborn birthweight. Maternal stress was investigated as independent measures, principal components, and clusters identified through machine learning. The transcriptome was assayed using the ClariomD chip. Multiple regression models were used to test for associations between maternal stress measures, the transcriptome, and newborn birthweight.ResultsNone of the maternal stress measures showed an association with the expression of individual genes. In contrast, when testing global gene expression, war trauma was significantly associated with the placental transcriptome. War trauma was also significantly associated with birthweight in multiple models. Mediation analysis indicated that ~14% of the effect of war trauma on birthweight was mediated by a placental gene expression component.DiscussionOur results suggest that gene expression in the placenta, which represents the interface between mother and developing fetus, may partially mediate the negative impact of maternal stress on newborn birthweight.
Establishment of organoid models for pancreatic ductal adenocarcinoma and screening of individualized therapy strategy
Authors: Gong Miaomiao , Meng Han , Tan Dengxu , Li Peng , Qin Jing , An Qingling , Shi Changhong , An Jiaze 
Published: October 2023

AbstractBackgroundPatients with pancreatic ductal adenocarcinoma (PDAC) who undergo surgical resection and receive effective chemotherapy have the best chance for long‐term survival. Unfortunately, because of the heterogeneity of pancreatic cancer, it is difficult to find a personalized treatment strategy for patients. Organoids are ideal preclinical models for personalized medicine. Therefore, we explore the cultivation conditions and construction methods of PDAC organoid models to screen the individualized therapy strategy.MethodsFresh PDAC tissues from surgical resection were collected and digested with digestive enzymes; then the tumor cells were embedded in Matrigel with a suitable medium to establish the PDAC organoid models. The genetic stability of the organoids was analyzed using whole exon sequencing; hematoxylin and eosin staining and immunohistochemistry of organoids were performed to analyze their consistency with the pathological morphology of the patient's tumor tissue; After 2 days of organoid culture, we selected four commonly used clinical chemotherapy drugs for single or combined treatment to analyze drug sensitivity.ResultsTwo cases of PDAC organoid models were successfully established, and the results of their pathological characteristics and exome sequencing were consistent with those of the patient's tumor tissue. Both PDAC organoids showed more sensitivity to gemcitabine and cisplatin, and the combined treatment was more effective than monotherapy.ConclusionBoth organoids better retained the pathological characteristics, genomic stability, and heterogeneity with the original tumor. Individual PDAC organoids exhibited different sensitivities to the same drugs. Thus, this study provided ideal experimental models for screening individualized therapy strategy for patients with PDAC.
Effective electrocatalytic hydrogen evolution of carbon paste electrode modified by Fe (II) and Ni (II) phenylimidazole‐dicarboxylate complexes
Authors: Gao Wei , Fei Cailing , Wu Zhengwei , Lv Yue , Zhang Jiaqi , Wu Huilu 
Published: October 2023

The structure determined is helpful to explore the reaction mechanism and provide a design strategy for the synthesis of high‐performance hydrogen evolution reaction (HER) electricity catalysts. Therefore, two structurally tunable and deterministic metal complexes, [Fe(m‐H2MOPhIDC)2(H2O)2]·2H2O (1) and [Ni(m‐HMOPhIDC)(H2O)2)]n (2) (m‐H3MOPhIDC = 2‐[3‐methoxyphenyl]‐1H‐imidazole‐4,5‐dicarboxylic acid), were synthesized under solvothermal conditions and used to assemble modified carbon paste electrodes (CPE 1–2) to explore the relationship between structure and catalytic performance. Structural analysis revealed that complexes 1 and 2 had a mononuclear structure and 1D linear structure, respectively, and that the central ions of the two complexes had the same coordination environment of the octahedral spatial configuration. In 0.5 M H2SO4 and 293 K, linear sweep voltammetry and Tafel curve indicate that the η10 (overpotential, 10 mA cm−2) of two modified carbon paste electrodes are −574 and −539 mV and Tafel slopes are 161 and 128 mV dec−1. Comparing the overpotential of CPE 1–2 with that of unmodified solid carbon paste electrode (sCPE, −976 mV), it was found that the overpotential of CPE1–2 shifted positively and the Tafel slopes are obviously reduced compared to sCPE (221 mV dec−1), which proves that the CPE 1–2 has effective electrocatalytic hydrogen evolution activity. The controlled potential electrolysis and impedance spectroscopy further validated the above conclusions. The higher HER activity of the CPE 2 than CPE 1 can be attributed to the fact that complex 2 is a one‐dimensional polymer, which can efficiently disperse the catalytic active site. The use of metal complexes as HER electrocatalysts provides a new idea for an effective method for converting electric energy into hydrogen energy and is beneficial to the development of the HER research field.
1,2‐Bis(triazolyl)tetraphenyldigermanes: Synthesis, Structure and Properties
Authors: Zaitsev Kirill V. , Veshchitsky Gleb A. , Oprunenko Yuri F. , Kharcheva Anastasia V. , Moiseeva Anna A. , Gloriozov Igor P. , Lermontova Elmira Kh. 
Published: October 2023

AbstractUsing the [3+2] cycloaddition reaction of [HC≡C−GePh2−]2 (1) and a number of RCH2N3, this work described the synthesis of a series of novel heterocyclic digermanes, bitriazoles [1,4‐C2HN3(CH2R)GePh2−]2, 2–12 (R=Ph, p‐Tol, p‐C6H4NMe2, p‐C6H4OMe, p‐C6H4Br, m‐C6H4NO2, 2‐Naphth, CH2‐p‐OC6H4CHO, CH2‐p‐OC6H4COOMe, CH2P(O)(OEt)2, COOEt), difficult to produce by other methods. The structural peculiarities of these compounds were studied in detail by NMR spectroscopy and by XRD analysis (for 6, 9 and 10). The properties of 1–12 were studied by UV/vis and luminescence emission spectroscopy, electrochemistry and DFT calculations, indicating an effective conjugation in their molecules.
One‐year outcomes after prostate artery embolization versus laser enucleation: A network meta‐analysis
Authors: Bhatia Ansh , Porto Joao Gabriel , Maini Aneesha , Langade Deepak , Herrmann Thomas R. W. , Shah Hemendra Navinchandra , Bhatia Shivank 
Published: October 2023

AbstractBackgroundAlthough holmium laser enucleation (HoLEP) is considered a size‐independent procedure for treatment of an enlarged prostate, prostate artery embolization (PAE) is emerging as an alternative modality to treat moderate and large benign prostatic hyperplasia. This study aims to compare the early post‐operative and short‐term efficacy of PAE and HoLEP.MethodsPubMed, Cochrane Library and EMBASE databases were searched. Network meta‐analysis was performed following PRISMA‐N‐guidelines. Post‐operative parameters analysed include international prostate symptom score (IPSS), quality of life (QOL), post‐void residual urine (PVR), maximal uroflow rate (Qmax) and serious adverse events (SAE). Random effects model calculated weighted mean differences (WMD). If 95%CI crossed the line of no effect (WMD = 0), evidence indicated no statistically significant difference between treatments compared.ResultsQualitative and quantitative syntheses included 20 and 18 studies with 1991 and 1606 patients, respectively. At 3 months, there was no statistically significant difference between PAE and HoLEP in IPSS score improvement [WMD: −2.21: 95%CI: (−10.20, 5.78), favouring PAE], QoL score improvement [WMD: −0.22:95%CI: (−1.75, 1.32), favouring PAE] and PVR improvement [WMD: 26.97: 95%CI: (−59.53, 113.48), favouring HoLEP]. However, PAE was found inferior to HoLEP for Qmax improvement [WMD: 8.47, 95%CI: (2.89, 14.05), favouring HoLEP]. At 1‐year follow‐up, there was no statistically significant was found between PAE and HoLEP for IPSS score improvement [WMD:6.03, 95%CI: (−1.30, 13.35)], QoL score improvement [WMD: 0.03, 95%CI: (−1.19, 1.25)], PVR improvement [WMD:4.11, 95%CI: (−32.31, 40.53)] and Qmax improvement [WMD:2.60, 95%CI: (−2.20, 7.41)] with all differences favouring HoLEP. PAE was superior to HoLEP for SAE [PAE vs. HoLEP‐OR: 0.68, 95%CI: (0.25, 1.37)].ConclusionHoLEP was superior to PAE at 3 months for Qmax improvement. There was no significant difference in IPSS, QoL, PVR and Qmax improvement at 1 year between PAE and HoLEP. PAE was also associated with lesser SAE compared to HoLEP. Studies on the long‐term outcome of PAE are needed to establish the durability of early outcomes after PAE.
Isotope effects on radical pair performance in cryptochrome: A new hypothesis for the evolution of animal migration
Authors: Galván Ismael , Hassasfar Abbas , Adams Betony , Petruccione Francesco 
Published: October 2023

AbstractMechanisms occurring at the atomic level are now known to drive processes essential for life, as revealed by quantum effects on biochemical reactions. Some macroscopic characteristics of organisms may thus show an atomic imprint, which may be transferred across organisms and affect their evolution. This possibility is considered here for the first time, with the aim of elucidating the appearance of an animal innovation with an unclear evolutionary origin: migratory behaviour. This trait may be mediated by a radical pair (RP) mechanism in the retinal flavoprotein cryptochrome, providing essential magnetic orientation for migration. Isotopes may affect the performance of quantum processes through their nuclear spin. Here, we consider a simple model and then apply the standard open quantum system approach to the spin dynamics of cryptochrome RP. We changed the spin quantum number (I) and g‐factor of hydrogen and nitrogen isotopes to investigate their effect on RP's yield and magnetic sensitivity. Strong differences arose between isotopes with I = 1 and I = 1/2 in their contribution to cryptochrome magnetic sensitivity, particularly regarding Earth's magnetic field strengths (25–65 µT). In most cases, isotopic substitution improved RP's magnetic sensitivity. Migratory behaviour may thus have been favoured in animals with certain isotopic compositions of cryptochrome.
Effects of green and circular products' features on consumers' choice of remanufactured smartphones
Authors: Kerber Jaqueline Carneiro , Fettermann Diego Castro , Bouzon Marina 
Published: October 2023

AbstractPurchasing green products is one of the cornerstones to promote sustainable development since the negative impact of these products is lower than traditional goods. In a Circular Economic (CE) context, green products begin to encompass reconditioned products reintroduced to the production and consumption cycle, such as remanufactured products. Many green products and remanufactured products' features intersect; however, the consumers' perception of these two products is not equal. The present work analyses the consumers' intention to purchase remanufactured products in the Southern Brazil, in a CE context. To that end, 228 consumers from Southern Brazil answered a stated preference questionnaire with different scenarios of remanufactured smartphones with warranty, label and discount. Results indicate that warranty, label, and discount positively impact the consumers' choice towards remanufactured smartphones. Furthermore, results indicate that consumers would be willing to give up more on the discount in order to have a scenario where the remanufactured smartphone has a label and warranty. This study contributes to the literature on consumers' perception and purchase intention towards remanufactured products in emerging economies, which is still scarce. Furthermore, the industry might benefit from this work since understanding what affects consumers' purchase intention may help redirect marketing strategies to increase demand and competitiveness.
Crithmum maritimum L. Volatile Compound's Diversity Through Tunisian Populations: Use of a Plant Organ‐Based Statistical Approach for Chemotype Identification
Authors: Jallali Inès , Hannachi Hédia , Zaouali Yosr , Smaoui Abderrazek , Abdelly Chedly , Ksouri Riadh 
Published: October 2023

AbstractThis work aimed to investigate the variability of the chemical composition of the aromatic halophyte Crithmum maritimum L. essential oils according to the geographical origin and separated organs, using a statistical approach based on the multiple analysis of variance and the Principal Component Analyses. One hundred twenty samples were collected from three distinct bioclimatic regions (10 samples×3 provenances×4 organs). Hydrodistillation of separated organs (roots, stems, leaves and flowers) yielded 0.13 to 1.75 % of the dry matter. Chemical investigation of the volatile compounds by Gas chromatography‐mass spectrometry showed that C. maritimum essential oils were dominated by monoterpenes hydrocarbons, oxygenated monoterpenes, and phenylpropanoids varying, respectively, from 33.3 to 66.9, from 7.8 to 46.6 and from 4.5 to 57.2 % according to organs and localities. Statistical analyses identified three different chemotypes depending on the geographic origin as follow: γ‐Terpinene‐Thymol methyl ether / Dillapiole / Thymol methyl ether‐Dillapiole.
In Vitro and in Silico Studies of Lichen Compounds Atranorin and Salazinic Acid as Potential Antioxidant, Antibacterial and Anticancer Agents
Authors: Gaikwad Subhash B. , Mapari Sachin V. , Sutar Ruchira R. , Syed Muntjeeb , Khare Roshni , Behera Bhaskar C. 
Published: October 2023

AbstractLichens are symbiotic organisms made up of alga/cyanobacterium and fungus. We investigated antioxidant, antibacterial and anticancer properties of two lichen compounds, atranorin and salazinic acid, and five lichen species: Heterodermia boryi, Heterodermia diademata, Heterodermia hypocaesia, Parmotrema reticulatum, and Stereocaulon foliolosum. Free radical scavenging, Ferric reducing potential, Nitric oxide scavenging, and Trolox equivalent capacity were used to measure antioxidant activity. Strong radical scavenging action was demonstrated by atranorin and salazinic acid, with IC50 values of 39.31 μM and 12.14 μM, respectively. The Minimum Inhibitory Concentration (MIC) assay based on resazurin, was used to measure antibacterial activity. Parmotrema reticulatum demonstrated significant antibacterial activity against Raoultella planticola with MIC of 7.8 μg/mL. Cytotoxicity assay on breast cancer cell line was used to assess anticancer activity. To further understand the binding locations on the target proteins Er (Estrogen Receptor alpha), EGFR (Epidermal Growth Factor Receptor), mTOR (Mammalian Target of Rapamycin), and PgR (Progesterone Receptor), molecular docking experiments were conducted. Docking study showed that the binding energies of atranorin and salazinic acid with mTOR were −5.31 kcal/mol and −3.43 kcal/mol, respectively. The results suggest that atranorin has the potential to be a multitargeted molecule with natural antioxidant, antibacterial, and anticancer properties.
Right ventricular remodeling and clinical outcomes following transcatheter tricuspid valve intervention
Authors: Dershowitz Lyle , Lawlor Matthew K. , Hamid Nadira , Kampaktsis Polydoros , Ning Yuming , Vahl Torsten P. , Nazif Tamim , Khalique Omar , Ng Vivian , Kurlansky Paul , Leon Martin , Hahn Rebecca , Kodali Susheel , George Isaac 
Published: October 2023

AbstractAimsCharacterize the impact of residual tricuspid regurgitation (TR) on right ventricle (RV) remodeling and clinical outcomes after transcatheter tricuspid valve intervention.MethodsWe performed a single‐center retrospective analysis of transcatheter tricuspid valve repair (TTVr) or replacement (TTVR) patients. The primary outcomes were longitudinal tricuspid annular plane systolic excursion (TAPSE), fractional area change (FAC), pulmonary artery systolic pressure (PASP), and RV dimensions (RVd). We used multivariable linear mixed models to evaluate association with replacement versus repair and degree of TR reduction with changes in these echo measures over time. Multivariable Cox regression was used to identify associations between changes in these echo measures and a composite clinical outcome of death, heart failure hospitalization, or re‐do tricuspid valve intervention.ResultsWe included a total of 61 patients; mean age was 77.5 ± 11.7 and 62% were female. TTVR was performed in 25 (41%) and TTVr in 36 (59%). Initially, 72% (n = 44) had ≤ severe TR and 28% (n = 17) had massive or torrential TR. The median number of follow up echos was 2: time to 1st follow‐up was 50 days (interquartile range [IQR]: 20, 91) and last follow‐up was 147 (IQR: 90, 327). Median TR reduction was 1 (IQR: 0, 2) versus 4 (IQR: 3, 6) grades in TTVr versus TTVR (p < 0.0001). In linear mixed modeling, TTVR was associated with decline in TAPSE and PASP, and TR reduction was associated with decreased RVd. In multivariable Cox regression, greater RVd was associated with the clinical outcome (hazard ratio: 9.27, 95% confidence interval: 1.23–69.88, p = 0.03).ConclusionGreater TR reduction is achieved by TTVR versus TTVr, which is in turn associated with RV reverse remodeling. RV dimension in follow‐up is associated with increased risk of a composite outcome of death, heart failure hospitalization, or re‐do tricuspid valve intervention.
Balloon‐assisted leaflet modification: Gaining momentum with innovative approaches
Authors: McCabe James M. , Helmy Tarek 
Published: October 2023

Key Points
Transcatheter mitral valve replacement (TMVR) is expanding.
The risk of left ventricular outflow tract obstruction (LVOTO) remains a challenge.
Balloon‐assisted leaflet modification is a reasonable approach to mitigate LVOTO, especially with innovative approaches.