bluuebunny/crossref_metadata_2025_split huggingface dataset:
Education for Sustainability: Innovative Teaching on Photosynthesis of Aquatic Plants in Ecological Context
Authors: Ryplova Renata , Pokorny Jan , Baxa Marek 
Published: October 2023

Eutrophication due to high load of nutrients from the catchment is significant worldwide problem causing impairment of water ecosystems and water quality. The reason is tight connection of eutrophication with photosynthetic biomass production of blue green algae resulting in extreme changes of oxygen level, anoxia at the bottom and release of toxic substances in water. Acceleration and extension of eutrophication due to human activities together with insufficient human understanding of the ecological role of photosynthesis of aquatic plants leads to inappropriate water and landscape management resulting in further loss of clear water. To save enough clear water supplies for future generation it is necessary to improve human understanding of these processes starting already from school education. This contribution brings results of a survey aimed on the impact of developed innovative teaching activity on photosynthetic biomass production of aquatic plants in ecological context and using digital technologies which was implemented into the education at Czech upper secondary schools. Significant improvement of student understanding of ecological function of photosynthetic biomass production in water and increase of attractiveness of plant education for students were proved. The contribution of innovative teaching on photosynthetic biomass production in ecological context for sustainable education is discussed.
Keywords: Plant blindness, Aquatic plants, Eutrophication, Sustainable Education, Water.
Gastric Alimetry Expands Patient Phenotyping in Gastroduodenal Disorders Compared with Gastric Emptying Scintigraphy
Authors: Wang William Jiaen , Foong Daphne , Calder Stefan , Schamberg Gabriel , Varghese Chris , Tack Jan , Xu William , Daker Charlotte , Carson Daniel , Waite Stephen , Hayes Thomas , Du Peng , Abell Thomas L. , Parkman Henry P. , Huang I-Hsuan , Fernandes Vivian , Andrews Christopher N. , Gharibans Armen A. , Ho Vincent , O'Grady Greg 
Published: October 2023

INTRODUCTION:
Gastric emptying testing (GET) assesses gastric motility, however, is nonspecific and insensitive for neuromuscular disorders. Gastric Alimetry (GA) is a new medical device combining noninvasive gastric electrophysiological mapping and validated symptom profiling. This study assessed patient-specific phenotyping using GA compared with GET.

METHODS:
Patients with chronic gastroduodenal symptoms underwent simultaneous GET and GA, comprising a 30-minute baseline, 99mTC-labelled egg meal, and 4-hour postprandial recording. Results were referenced to normative ranges. Symptoms were profiled in the validated GA App and phenotyped using rule-based criteria based on their relationships to the meal and gastric activity: (i) sensorimotor, (ii) continuous, and (iii) other.

RESULTS:
Seventy-five patients were assessed, 77% female. Motility abnormality detection rates were as follows: GET 22.7% (14 delayed, 3 rapid), GA spectral analysis 33.3% (14 low rhythm stability/low amplitude, 5 high amplitude, and 6 abnormal frequency), and combined yield 42.7%. In patients with normal spectral analysis, GA symptom phenotypes included sensorimotor 17% (where symptoms strongly paired with gastric amplitude, median r = 0.61), continuous 30%, and other 53%. GA phenotypes showed superior correlations with Gastroparesis Cardinal Symptom Index, Patient Assessment of Upper Gastrointestinal Symptom Severity Index, and anxiety scales, whereas Rome IV Criteria did not correlate with psychometric scores (P > 0.05). Delayed emptying was not predictive of specific GA phenotypes.

DISCUSSION:
GA improves patient phenotyping in chronic gastroduodenal disorders in the presence and absence of motility abnormalities with increased correlation with symptoms and psychometrics compared with gastric emptying status and Rome IV criteria. These findings have implications for the diagnostic profiling and personalized management of gastroduodenal disorders.
Colorectal Cancer Screening Receipt Does Not Differ by 10-Year Mortality Risk Among Older Adults
Authors: Liu Po-Hong , Singal Amit G. , Murphy Caitlin C. 
Published: October 2023

BACKGROUND:Health status and life expectancy are important considerations for assessing potential benefits and harms of colorectal cancer (CRC) screening programs, particularly among older adults.METHODS:We examined receipt of past-year CRC screening according to predicted 10-year mortality risk among 25,888 community-dwelling adults aged 65–84 years who were not up-to-date with screening in the nationwide National Health Interview Survey. Ten-year mortality risk was estimated using a validated index; from the lowest to highest quintiles of the index, risk was 12%, 24%, 39%, 58%, and 79%, respectively. We also examined the proportion of screening performed among adults with life expectancy <10 years.RESULTS:The prevalence of past-year CRC screening was 39.5%, 40.6%, 38.7%, 36.4%, and 35.4%, from the lowest to highest quintile of 10-year mortality risk. Odds of CRC screening did not differ between adults in the lowest vs highest quintile (adjusted odds ratio 1.05, 95% confidence interval: 0.93–1.20). One-quarter (27.9%) of past-year CRC screening occurred in adults with life expectancy <10 years, and more than half (50.7%) of adults aged 75–84 years had 10-year mortality risk ≥50% at the time of screening. In an exploratory analysis, invasive but not noninvasive screening increased as 10-year mortality risk increased (P< 0.05) among adults aged 70–79 years.DISCUSSION:Past-year CRC screening does not differ by predicted 10-year mortality risk. An age-based approach to CRC screening results in underscreening of older, healthier adults and overscreening of younger adults with chronic conditions. Personalized screening with incorporation of individual life expectancy may increase the value of CRC screening programs.
Machine learning to optimize cerebrospinal fluid dilution for analysis of MRZH reaction
Authors: Turčić Ana , Štajduhar Andrija , Vogrinc Željka , Zaninović Ljiljana , Rogić Dunja 
Published: October 2023

Abstract

Objectives
To create a supervised machine learning algorithm aimed at predicting an optimal cerebrospinal fluid (CSF) dilution when determining virus specific antibody indices to reduce the need for repeated tests.

Methods
The CatBoost model was trained, optimized, and tested on a dataset with five input variables: albumin quotient, immunoglobulin G (IgG) in CSF, IgG quotient (QIgG), intrathecal synthesis (ITS) and limes quotient (LIM IgG). Albumin and IgG concentrations in CSF and serum were performed by immunonephelometry on Atellica NEPH 630 (Siemens Healthineers, Erlangen, Germany) and ITS and LIM IgG were calculated according to Reiber. Concentrations of IgG antibodies to measles, rubella, varicella zoster and herpes simplex 1/2 viruses were analysed in CSF and serum by ELISA (Euroimmun, Lübeck, Germany). Optimal CSF dilution was defined for each virus and used as a classification variable while the standard operating procedure was set to start at 2×-dilution of CSF.

Results
The dataset included 571 samples with the imbalanced distribution of the optimal CSF dilutions: 2× dilution n=440, 3× dilution n=109, 4× dilution n=22. The optimized CatBoost model achieved an area under the curve (AUC) score of 0.971, and a test accuracy of 0.900. The model falsely classified 14 (9.9 %) samples of the testing set but reduced the need for repeated testing compared to the standard protocol by 42 %. The output of the CatBoost model is mostly dependant on the QIgG, ITS and CSF IgG variables.

Conclusions
An accurate algorithm was achieved for predicting the optimal CSF dilution, which reduces the number of test repeats.
Updating constructions: additive effects of prior and current experience during sentence production
Authors: Thothathiri Malathi , Levshina Natalia 
Published: October 2023

Abstract
While much earlier work has indicated that prior verb bias from lifelong language experience influences language processing, recent findings highlight the fact that verb biases induced during lab-based exposure sessions also influence processing. We investigated the nature of updating, i.e., how prior and current experience might interact in guiding subsequent sentence production. Participants underwent a short training session where we manipulated the bias of known English dative verbs. The prior bias of each verb for the double-object (DO) versus the prepositional-object (PO) dative was estimated using a corpus. Current verb bias was counterbalanced and controlled experimentally. Bayesian mixed-effects logistic models of participants’ responses (DO or PO) during subsequent free-choice production showed that both the prior and current verb biases affected speakers’ construction choice. These effects were additive and not interactive, contrary to the prediction from error-based learning models. Semantic similarity to other verbs and their experimentally manipulated biases influenced sentence production, consistent with item-based analogy and exemplar theory. These results shed light on the potential mechanisms underlying language updating and the adaptation of sentence production to ongoing experience.
Lessons learned from a case study on teaching the socioscientific issue of ethanol, used as an ingredient of sanitizers, to promote students’ learning of and about chemistry during the COVID-19 pandemic
Authors: Ambrogi Paola , Eilks Ingo 
Published: October 2023

AbstractDuring the COVID-19 pandemic, the unexpected lockdown of schools brought many challenges to redesigning the teaching and learning of chemistry at the secondary schooling level. The demand for online teaching under COVID-19 conditions was, however, also an opportunity to reflect on introducing new content, pedagogies, and media. This paper reflects on the implementation of a chemistry lesson plan focusing on the socio-scientific issue of ethanol used for hand sanitizers in Italy. Ethanol is possibly the most common ingredient of hand sanitizer lotions and provides an authentic context for the learning of and about chemistry. The objective was to promote students’ awareness of the deep interconnections between science, society, ethics, and the environment through a socio-scientific issues-based approach.
Gabriel, Narciso de (2023). "Os mestres mortos daquel verán". Vigo, Galaxia. ISBN: 978-84-9151-969-0. 245 páxinas
Authors: Porto Ucha Ángel Serafín 
Published: October 2023

Referencia bibliográfica sobre o libro recentemente publicado por Narciso de Gabriel Fernández, Os mestres mortos daquel verán, na Editorial Galaxia de Vigo. É unha investigación que recorre as vidas e mortes de dez mestres e mestras que exercían na provincia da Coruña e que foron executados baixo diferentes acusacións. A obra segue unha liña iniciada polo autor fai tempo, con moito rigor, e complementada por outros historiadores da educación galegos, que analizan as provincias de Pontevedra (Porto Ucha e Vázquez Ramil), Lugo (Costa Rico e Bolaño Amigo) e Ourense (Cid Fernández). Dende o punto de vista editorial é un libro moi coidado e ten o raro mérito de conxugar a investigación seria coa divulgación ben feita.
La influencia del pensamiento de Patrice Lumumba en la internacionalización de la crisis de Katanga
Authors: Olmedo Alberca Ana 
Published: October 2023

El objetivo del presente artículo es analizar el impacto del pensamiento de Patrice Lumumba en el transcurso y la internacionalización de la crisis causada por la secesión de la provincia de Katanga (República Democrática del Congo) entre 1960 y 1963. La figura del que sería el primer ministro de la recién constituida República Democrática del Congo, antiguo Congo belga, experimenta una evolución de pensamiento desde de la connivencia con la presencia belga hasta el rechazo de la intromisión occidental. Es precisamente este viraje el que le pone en el punto de mira de comunidad internacional, la cual, en el contexto histórico caracterizado por el inicio de las descolonizaciones y la Guerra Fría, interpreta sus movimientos como un acercamiento al bloque comunista, suscitando la intervención de actores internos y externos al continente africano.
Partiendo del análisis de su pensamiento a través de sus principales discursos, se realizará una breve contextualización histórica para pasar a abordar la transformación del mismo, los tres pilares que lo conforman (anticolonialismo, panafricanismo y centralismo) y los factores endógenos y exógenos que frustraron su proyecto político, y que hacen de esta crisis uno de los ejemplos más paradigmáticos de neocolonialismo.
Benefits of probiotics in Autism Spectrum Disorders : A meta-analysis of RCTs
Authors: Hiremath Sharanabasayyaswamy B. , Devendrappa Srinivas L. 
Published: October 2023

Using probiotics as a pharmaceutical intervention is based on the fact that dysbiosis affects many people with autism spectrum disorders (ASD). This study aimed to quantify various probiotics’ overall and individualized benefits in treating ASD. Randomized or cross-over trials comparing the efficacy of placebo or active control vs. probiotics in patients of any age diagnosed with ASD based on DSM IV/V criteria were considered under inclusion criteria. An electronic database search in PUBMED and Cochrane Library was conducted using MeSH search terms “probiotics” AND “Autism.” Mean change in the total score of clinical parameters used to assess ASD symptom severity was the primary outcome measure analyzed. All the outcome measures were estimated by calculating the Standardized Mean Difference (SMD) values and their 95% Confidence Intervals (CI), considering the different clinical parameters used to assess the change in ASD symptoms in identified clinical trials. An insignificant decrease in the total score value of primary outcome measure by -0.14 (SMD: 0.14, 95% CI:-0.45 to 0.17) in patients treated with probiotics was observed. The quantity of decrease remained insignificant in subgroup analyses also. Observed insignificant clinical benefits of probiotics in ASD patients could be due to the presence of gastrointestinal symptoms as co-morbidity. We hypothesize that intolerance to dietary components is responsible for gastrointestinal symptoms and inflammation. Perhaps probiotics are still beneficial in ASD patients without gastrointestinal symptoms, while their combination with prebiotics is effective in patients with gastrointestinal symptoms.
Adoption of Vaping Cessation Methods by US Adolescent E-Cigarette Users
Authors: Dai Hongying Daisy , Hanh Pham , Guenzel Nick , Morgan Mathuri , Kerns Ellen , Winickoff Jonathan P. 
Published: October 2023

BACKGROUND
A large number of adolescent e-cigarette users intend to quit vaping or have past-year quit attempts. However, it remains unknown which methods they use in their vaping cessation efforts.

METHODS
We analyzed current (past 30-day) e-cigarette users who made ≥1 quit attempt in the past 12 months from the 2021 National Youth Tobacco Survey (NYTS) to examine the prevalence and associations of sociodemographic factors, vaping behaviors, and harm perception with the adoption of different vaping cessation methods.

RESULTS
In the 2021 NYTS, there were 1436 current vapers, and 889 (67.9%) had made a past-year quit attempt. Of those, 575 (63.7%) (weighted N = 810 000) reported they did not use any resources (unassisted quitting). Peer support (14.2%), help on the Internet (6.4%), a mobile app or text messaging (5.9%), and parent support (5.8%) were the top 4 cessation methods. Female (versus male) vapers were less likely to solicit parent support (adjusted odds ratio [AOR], 0.2; 95% confidence interval [95% CI], 0.1–0.5), whereas Hispanic (versus White) vapers were more likely to seek friend support (AOR, 2.1; 95% CI, 1.1–3.9) and parent support (AOR, 2.7, 95% CI, 1.2–6.3). Those who perceived vaping to be harmful were less likely to get friend support, but more likely to use a mobile app or text messaging program. Dual users of e-cigarettes and any other tobacco product were more likely to get help from a teacher/coach or a doctor/health care provider and treatment from medical facilities than sole e-cigarette users.

CONCLUSIONS
There were different correlates with the adoption of vaping cessation methods, highlighting the need for tailored approaches to meet the cessation needs and preferences of the adolescent vaping population.
Influence of PMMA particle size control on the transmittance of PMMA/tempo-oxidized cellulose composites
Authors: Altarugio Julia P. , Staffa Lucas H. , Carvalho Antonio J. F. , Almeida Juliana M. P. 
Published: October 2023

AbstractCellulose is a class of biopolymers that prominently contributes to developing lightweight, eco-friendly, and biodegradable plastics. Among them, nanofibrillated cellulose (NFC) is one of the most interesting due to its mechanical behavior. Mixing it with synthetic plastic such as poly(methyl methacrylate) (PMMA) reduces synthetic polymer usage, agro-industrial residue and develops fiber-reinforced composites. NFC was prepared from residual biomass and oxidized with TEMPO (2,2,6,6-tetramethylpiperidine-1-oxyl radical). Herein, NFC was incorporated (25, 50 and 75 wt%) in a colloidal emulsion of PMMA, with PMMA particle size control (50 and 175 nm). The investigation of this system on the PMMA/NFC transparency was addressed here. FTIR and SEM demonstrated effective incorporation of NFC and interaction with the PMMA. The increment of NFC increased the water contact angle and improved film transparency. Paired with PMMA particle size control, particularly at 50 nm, this favored composite transparency, becoming close to or even greater than pure NFC.
Graphical abstract
Sex and gender differences in health and disease. Part I. Evolutionary
Authors: Drapkina O. M. , Kim O. T. 
Published: October 2023

Sex affects many aspects of a person's existence, including health. Life expectancy is one of the most telling examples of differences between the sexes. Almost all over the world, women have been found to live longer than men, but the gap in life expectancy varies considerably from country to country. The review discusses the evolutionary mechanisms behind this difference and potential strategies for increasing male life expectancy. Likely processes leading to sex-specific morbidity are also considered.
CLINICAL CASE OF A PATIENT WITH EXTREME HYPERTROPHIC CARDIOMYOPATHY AND RECURRENT IDIOPATHIC TRANSUDATIVE PERICARDIAL EFFUSION
Authors: Dren’ Elena V. , Sogoyan Nerses K. , Lyapina Irina N. , Golubovskaya Daria P. , Pecherina Tamara B. , Barbarash Olga L. 
Published: October 2023

HighlightsWe report a case of a patient with extreme hypertrophic cardiomyopathy and complex cardiac pathology undergoing heart transplantation. The article will be useful for cardiologists, therapists and cardiovascular surgeons. AbstractWe present a case of a patient with extreme hypertrophic cardiomyopathy, Wolff–Parkinson–White syndrome and nonspecific chronic exudative pericardial effusion with recurrent idiopathic transudative pericardial effusion. This case involves several approaches to treatment – medication and surgery for treating a patient with combined cardiomyopathy and pericardial effusion, which served as a “bridge” for a later change inro radical treatment - orthotopic heart transplantation.
HYPERTENSIVE DISORDERS OF PREGNANCY – MANAGEMENT STRATEGIES IN THE POSTPARTUM PERIOD (LITERATURE REVIEW)
Authors: Rudaeva Elena V. , Kashtalap Vasily V. , Marciyash Alexey A. , Moses Vadim G. , Savchenko Yana A. , Moses Kira B. , Elgina Svetlana I. , Rudaeva Elena G. 
Published: October 2023

HighlightsHypertensive disorders of pregnancy are associated with short- and long-term risks for the mother.We have identified several key points in the management strategy of this pathology in the postpartum period, which should contribute to the emergence of new directions in the prognosis and treatment modalities of this disease. AbstractThe article presents an analytical review of modern data on the treatment of hypertensive disorders of pregnancy (HDP) in the postpartum period. HDPs lead to maternal morbidity and mortality in developing and poor countries, and in regions with well-developed healthcare systems as well. HDPs can later progress into hypertension and are associated with the risk of coronary artery disease and stroke. Moreover, HDPs increase the likelihood of low-birth-weight babies and preterm births. The incidence of HDP is growing worldwide despite the implemented prevention methods: according to the Global Health Data Exchange, from 1990 to 2019 HDPs` incidence by 10.9% from 16.3 million to 18.08 million people. However, the introduction of universal approaches to prevention of complications made it possible to reduce mortality from HDP in the same period by 30.05%. The risk of hypertensive complications increases significantly in the postpartum period. Modern research confirms this – the likelihood of worsening HDP and the development of complications increases significantly in the first 24–48 hours after childbirth. About one third of cases of eclampsia occur in the postpartum period, of which almost half occur 48 hours after delivery. Stroke in women with HDP occurs in the postpartum period in half of the cases. Arterial hypertension (AH) in the postpartum period often requires an increase in doses of antihypertensive drugs, whereas after 3–6 months, many patients no longer need such therapy. During the first year after childbirth, the risk of progression of AH and the development of complications due to hypertension is increased, and remains so for many years. The feasibility of antihypertensive therapy in HDP today is beyond doubt, however, there are issues that require further study. They are related to the safety of prescribed drugs during lactation, and as a result, in many guidelines, antihypertensive therapy in the postpartum period is prescribed with reservations. Another problem is the relatively small number of RCTs directly assessing the effectiveness of antihypertensive therapy in the postpartum period.