bluuebunny/crossref_metadata_2025_split huggingface dataset:
cis‐ and trans‐Stereoselective Epoxidation of N‐Protected 2‐Cyclohexen‐1‐ylamines.
Authors: O'Brien Peter , Childs Amanda C. , Ensor Gareth J. , Hill Cheryl L. , Kirby Jonathan P. , Dearden Michael J. , Oxenford Sally J. , Rosser Clare M. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Transformations of Metallacycles. Part 31. Catalysts Based on Cobalt Complexes in Reactions of Trialkyl‐ and Alkylhaloalanes with Olefins, Allenes, and Acetylenes.
Authors: Ibragimov A. G. , Khafizova L. O. , Gil'fanova G. N. , Yakupova L. R. , Borisova A. L. , Dzhemilev U. M. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Directed Regio‐ and Stereoselective Hydroformylation of Mono‐ and 1,3‐Disubstituted Allylic Alcohols: A Catalytic Approach to the anti‐Aldol‐Retron.
Authors: Breit Bernhard , Demel Peter , Gebert Antje 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Fluorinated (Hetero)cycles via Ring‐Closing Metathesis of Fluoride‐ and Trifluoromethyl‐Functionalized Olefins.
Authors: De Matteis Valeria , van Delft Floris L. , de Gelder Rene , Tiebes Joerg , Rutjes Floris P. J. T. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stereochemistry of the Synthesis of 1‐(2‐Cyano‐2‐methoxyiminoacetyl)‐3‐ethylurea and Its E‐Configuration Crystal Structure.
Authors: Greci Lucedio , Carloni Patricia , Mandrioli Odofredo , Righi Lara , Rizzoli Corrado , Sgarabotto Paolo 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Geminal Systems. Part 50. Synthesis and Alcoholysis of N‐Acyloxy‐N‐alkoxy Derivatives of Ureas, Carbamates, and Benzamides.
Authors: Shtamburg V. G. , Klots E. A. , Pleshkova A. P. , Avramenko V. I. , Ivonin S. P. , Tsygankov A. V. , Kostyanovsky R. G. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Medium‐Sized Cyclophanes. Part 66. Through‐Space Electronic Interactions on Acylation of 8,16‐Disubstituted [2.2]Metacyclophanes.
Authors: Yamato Takehiko , Okabe Ryo , Shigekuni Mitsuaki , Furukawa Tsuyoshi 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
[Bmim]PF6/RuCl3×xH2O: A Novel and Recyclable Catalytic System for the Oxidative Coupling of β‐Naphthols.
Authors: Yadav Jhillu S. , Reddy Basi V. S. , Gayathri Kamakolanu Uma , Prasad Attaluri R. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Base‐Induced Photocyclization of 1,2‐Diaryl‐1‐tosylethenes. A Mechanistically Novel Approach to Phenanthrenes and Phenanthrenoids.
Authors: Almeida Jesus F. , Castedo Luis , Fernandez Dolores , Neo Ana G. , Romero Victor , Tojo Gabriel 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of β‐Lactam from Acyl(arylcarbamoyl)‐S,S‐bis(alkylketene) Dithioacetal: Revised Structure of the Product from Thermal Cyclization of Acyl(arylcarbamoyl)‐S,S‐bis(alkylketene) Dithioacetal.
Authors: Choi Eun Bok , Yon Guy Hwan , Lee Hyeon Kyu , Yang Hee Cheol , Yoo Chung Youl , Pak Chwang Siek 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Synthesis of Benzo[b]furan and Indole Derivatives from 1,1‐Dibromo‐1‐alkenes Using a Tandem Pd‐Assisted Cyclization—Coupling Reaction.
Authors: Thielges Sabine , Meddah Emilie , Bisseret Philippe , Eustache Jacques 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Transformations of 3‐Ethoxycarbonyl‐2‐(N‐R‐thioureido)thiophenes.
Authors: Chumakova L. Yu. , Demchenko A. M. , Krasovsky A. N. , Dolishnyak T. V. , Lozinskii M. O. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 3‐Methylenepyrrolidines by Palladium‐Catalyzed [3 + 2] Cycloaddition of Alkylidenecyclopropanes with Imines.
Authors: Oh Byoung Ho , Nakamura Itaru , Saito Shinichi , Yamamoto Yoshinori 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Formation and Spectroscopic Characterization of the Dioxygen Adduct of a Heme—Cu Complex Possessing a Cross‐Linked Tyrosine—Histidine Mimic: Modeling the Active Site of Cytochrome c Oxidase.
Authors: Liu Jin‐Gang , Naruta Yoshinori , Tani Fumito , Chishiro Takefumi , Tachi Yoshimitsu 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Thermal Rearrangement of 3‐Hydroxy‐1H,3H‐quinoline‐2,4‐diones to 3‐Acyloxy‐2,3‐dihydro‐1H‐indol‐2‐ones.
Authors: Klasek Antonin , Koristek Kamil , Kafka Stanislav , Kosmrlj Janez 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Electrocatalytic Transformation of Malononitrile and Cycloalkylidenemalononitriles into Spirotricyclic and Spirotetracyclic Compounds Containing Cyclopropane and Pyrroline Fragments.
Authors: Elinson M. N. , Fedukovich S. K. , Zaimovskaya T. A. , Vereshchagin A. N. , Nikishin G. I. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Imidazole Derivatives as New Potent and Selective 20‐HETE Synthase Inhibitors.
Authors: Nakamura Toshio , Kakinuma Hiroyuki , Umemiya Hiroki , Amada Hideaki , Miyata Noriyuki , Taniguchi Kazuo , Bando Kagumi , Sato Masakazu 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 2‐Substituted Benzimidazoles by Reaction of o‐Phenylenediamine with Aldehydes in the Presence of Sc(OTf)3.
Authors: Nagata Kazuhiro , Itoh Takashi , Ishikawa Hiroyuki , Ohsawa Akio 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
4,5‐Disubstituted‐1,3‐oxazolidin‐2‐imine Derivatives: A New Class of Orally Bioavailable Nitric Oxide Synthase Inhibitor.
Authors: Ueda Shigeo , Terauchi Hideo , Yano Akihiro , Ido Motoharu , Matsumoto Masashi , Kawasaki Motoji 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Transformations of Nitrates (Nitro Esters) of Amino Alcohols Involving Both Functions. Part 1. Reaction with Alkali Metal Hydrogen Carbonates.
Authors: Korepin A. G. , Galkin P. V. , Glushakova N. M. , Perepelkina E. K. , Loginova M. V. , Lodygina V. P. , Ol'khov Yu. A. , Eremenko L. T. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Metalation Reactions. 34. Synthesis of 2‐(1‐Hydroxy‐1‐arylethyl)‐1,3‐benzoxathiol‐3‐oxide Derivatives.
Authors: Cabiddu Salvatore , Cadoni Enzo , Melis Stefana , Ianni Alen , Bernard Angela M. , Cabiddu Maria G. , De Montis Stefania , Fattuoni Claudia , Ianelli Sandra 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Methyl 2‐(5‐Arylidene‐2,4‐dioxotetrahydrothiazol‐3‐yl)propionates
Authors: Popov‐Pergal K. , Cuckovic L. , Rancic M. , Pergal M. , Djokovic D. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Four‐Component Coupling Reactions of Silylacetylenes, Allyl Carbonates, and Trimethylsilyl Azide Catalyzed by a Pd(0)—Cu(I) Bimetallic Catalyst. Fully Substituted Triazole Synthesis from Seemingly Internal Alkynes.
Authors: Kamijo Shin , Jin Tienan , Yamamoto Yoshinori 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Transformation of N‐(5‐Acetyl‐6‐methyl‐2‐oxo‐2H‐pyran‐3‐yl)benzamide with Hydrazines in the Presence of an Acidic Catalyst.
Authors: Vranicar Lidija , Polanc Slovenko , Kocevar Marijan 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of 6‐Amino‐4‐aryl‐5‐cyano‐3‐ (3‐cyanopyridin‐2‐ylthiomethyl)‐2,4‐dihydropyrano[2,3‐c]pyrazoles and Their Hydrogenated Analogues. Molecular Structure of 6‐Amino‐5‐cyano‐3‐(3‐cyano‐4,6‐dimethylpyridin‐2‐ylthiomethyl)‐4‐ (2‐nitrophenyl)‐2,4‐dihydropyrano[2,3‐c]pyrazole.
Authors: Rodinovskaya L. A. , Gromova A. V. , Shestopalov A. M. , Nesterov V. N. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Highly Potent PDE4 Inhibitors with Therapeutic Potential.
Authors: Ochiai Hiroshi , Ohtani Tazumi , Ishida Akiharu , Kusumi Kensuke , Kato Masashi , Kohno Hiroshi , Kishikawa Katuya , Obata Takaaki , Nakai Hisao , Toda Masaaki 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
One‐Pot Synthesis of 4,6‐Diaryl‐3‐cyanopyridine‐2(1H)‐thiones and Their Transformation to Substituted Thieno[2,3‐b;4,5‐b]dipyridines and Pyrido[3′,2′:4,5]thieno[3,2‐d]pyrimidines.
Authors: Shestopalov A. M. , Nikishin K. G. , Gromova A. V. , Rodinovskaya L. A. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Synthesis of Chiral 1,1,3‐Trisubstituted 1,2,3,4‐Tetrahydro‐β‐carbolines by the Pictet—Spengler Reaction of Tryptophan and Ketones: Conversion of (1R,3S)‐Diastereomers into Their (1S,3S)‐Counterparts by Scission of the C(1)—N(2) Bond.
Authors: Horiguchi Yoshie , Nakamura Masayoshi , Saitoh Toshiaki , Sano Takehiro 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reactions of 2‐Hydroxynaphthazarins with Cyclohexane‐1,2‐dione as a New Method for the Synthesis of Pyranonaphthazarin Systems.
Authors: Shestak O. P. , Balaneva N. N. , Anufriev V. Ph. , Denisenko V. A. , Glazunov V. P. , Novikov V. L. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Pyrrolopyrimidines. Part 5. Reaction of 6‐Amino‐1,3‐dimethylpyrrolo[3,4‐d]pyrimidine‐2,4(1H,3H)‐diones with 1,3‐Diketones.
Authors: Tsupak E. B. , Shevchenko M. A. , Pozharskii A. F. , Tkachenko Yu. N. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Bridgehead Reactions of 9‐Substituted 5,6,7,8,9,10‐Hexahydro‐5,9‐methanopyrimido[4,5‐b]azocin‐4(3H)‐ones.
Authors: Taylor Edward C. , Bhatia Beena 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Simple Synthesis of 1,2‐Dihydro‐5,6‐tri(tetra)methylenespiro(cyclopentane (cyclohexane)‐2‐thieno‐[2,3‐d]pyrimidine‐4(3H)‐thiones).
Authors: Dyachenko V. D. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Cycloaddition of 4,6‐Dimethylpyrimidine‐2‐sulfenyl Chloride at the Acetylene Bond.
Authors: Borisov A. V. , Borisova G. N. , Nikonova Yu. A. , Osmanov V. K. , Matsulevich Zh. V. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis of Novel Melanocortin 4 Receptor Agonists and Antagonists Containing a Succinamide Core.
Authors: Xi Ning , Hale Clarence , Kelly Michael G. , Norman Mark H. , Stec Markian , Xu Shimin , Baumgartner James W. , Fotsch Christopher 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Dipyrrolo[1,2‐a;2′,1′‐c]pyrazines. Part 6. Electrophilic Substitution in a Series of Dipyrrolo[1,2‐a;2′,1′‐c]pyrazine and 5,6‐Dihydrodipyrrolo[1,2‐a;2′,1′‐c]pyrazine Derivatives. Phosphorylation of Dipyrrolo[1,2‐a;2′,1′‐c]pyrazines.
Authors: Terenin V. I. , Sumtsova E. A. , Vatsadze S. Z. , Kabanova E. V. , Leshcheva I. F. , Pleshkova A. P. , Zyk N. V. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Properties of 1,3‐Diaryl‐5,6‐dihydro‐8H‐imidazo[2,1‐c]‐1,4‐oxazinium Bromides.
Authors: Demchenko A. M. , Shtil N. A. , Andrushko A. P. , Krasovsky A. N. , Chernega A. N. , Rusanov E. B. , Pirozhenko V. V. , Lozinskii M. O. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Trisubstituted 1,3,5‐Triazines. Part 6. Synthesis of 2,4,6‐Tris(acetonyl)‐1,3,5‐triazine.
Authors: Shastin A. V. , Godovikova T. I. , Korsunskii B. L. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reactions of N‐(2‐Chloroacetyl)‐α‐amino Acids with 3‐Cyanopyridine‐2(1H)‐thiones. New Promising Route to 3,4‐Dihydropyrido[3′,2′:4,5]thieno[3,2‐e][1,4]diazepine‐2(1H),5‐diones.
Authors: Fedorov A. E. , Shestopalov A. M. , Belyakov P. A. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Novel Synthesis of Azocine, Azepine, Oxocine, and Oxepine Derivatives by Palladium‐Catalyzed Medium‐Ring Formation from Bromoallenes.
Authors: Ohno Hiroaki , Hamaguchi Hisao , Ohata Miyo , Kosaka Shohei , Tanaka Tetsuaki 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Immobilized Cobalt/Rhodium Heterobimetallic Nanoparticle‐Catalyzed Silylcarbocyclization and Carbonylative Silylcarbocyclization of 1,6‐Enynes.
Authors: Park Kang Hyun , Jung Il Gu , Kim So Yeon , Chung Young Keun 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Reaction of β‐Nitro‐ and β‐Halo‐β‐nitroethenylphosphonates with Furan.
Authors: Kuzhaeva A. A. , Anisimova N. A. , Deiko L. I. , Berkova G. A. , Berestovitskaya V. M. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Preparation of 10‐Trifluoromethyl Artemether and Artesunate. Influence of Hexafluoropropan‐2‐ol on Substitution Reaction.
Authors: Magueur Guillaume , Crousse Benoit , Ourevitch Michele , Begue Jean‐Pierre , Bonnet‐Delpon Daniele 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Substituted 1,2‐Thiazetidine 1,1‐Dioxides. Synthesis and Properties of N‐Alkylated and N‐Acylated Derivatives of 1,2‐Thiazetidine‐3‐acetic Acid 1,1‐Dioxide.
Authors: Roehrich Till , Thaher Bassam Abu , Otto Hans‐Hartwig 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Bhimamycin A≈E and Bhimanone: Isolation, Structure Elucidation and Biological Activity of Novel Quinone Antibiotics from a Terrestrial Streptomycete.
Authors: Fotso Serge , Maskey Rajendra P. , Gruen‐Wollny Iris , Schulz Klaus‐Peter , Munk Morton , Laatsch Hartmut 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
EI‐2128‐1, a Novel Interleukin‐1β Converting Enzyme Inhibitor Produced by Penicillium sp. E‐2128.
Authors: Koizumi Fumito , Agatsuma Tsutomu , Ando Katsuhiko , Kondo Hidemasa , Saitoh Yutaka , Matsuda Yuzuru , Nakanishi Satoshi 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
New Quinones and Hydroquinones from Malbranchea cinnamomea HKI 286 and HKI 296 and Interaction with Tax/CREB Expression System in Yeast.
Authors: Schlegel Brigitte , Haenel Frank , Gollmick Friedrich A. , Saluz Hans‐Peter , Graefe Udo 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Synthesis and Pharmacological Evaluation of Prenylated and Benzylated Pterocarpans Against Snake Venom.
Authors: da Silva Alcides J. M. , Coelho Antonio L. , Simas Alessandro B. C. , Moraes Raphael A. M. , Pinheiro Diogo A. , Fernandes Fabricio F. A. , Arruda Emerson Z. , Costa Paulo R. R. , Melo Paulo A. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
MOCVD Growth, Micro‐Structural, and Superconducting Properties of a‐Axis Oriented TlBaCaCuO Thin Films.
Authors: Malandrino Graziella , Perdicaro Laura M. S. , Fragala Ignazio L. , Testa Alberto M. , Fiorani Dino 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Electrochemical Fabrication of Large‐Area, Ordered Bi2Te3 Nanowire Arrays.
Authors: Jin Chuangui , Xiang Xiaoqiang , Jia Chong , Liu Weifeng , Cai Weili , Yao Lianzeng , Li Xiaoguang 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Large‐Scale Synthesis of High‐Quality Double‐Walled Carbon Nanotubes by Catalytic Decomposition of n‐Hexane.
Authors: Lyu Seung Chul , Liu Bao Chun , Lee Su Hwan , Park Chong Yun , Kang Hee Kwang , Yang Cheol‐Woong , Lee Cheol Jin 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Design and Synthesis of Aminopropyl Tetrahydroindole‐Based Indolin‐2‐ones as Selective and Potent Inhibitors of Src and Yes Tyrosine Kinase.
Authors: Guan Huiping , Laird A. Douglas , Blake Robert A. , Tang Cho , Liang Chris 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
Chemical Substances and Contact Allergy‐244 Substances Ranked According to Allergenic Potency
Authors: Schlede E. , Aberer W. , Fuchs T. , Gerner I. , Lessmann H. , Maurer T. , Rossbacher R. , Stropp G. , Wagner E. , Kayser D. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
In situ Synthesis and Characterization of Fullerene Derivatives by Knudsen‐Cell Mass Spectrometry
Authors: Boltalina Olga V. , Goryunkov Alexey A. , Markov Vitaly Yu. , Ioffe Ilya N. , Sidorov Lev N. 
Published: April 2004

AbstractFor Abstract see ChemInform Abstract in Full Text.
A surrogate marker profile for PML/RARα expressing acute promyelocytic leukemia and the association of immunophenotypic markers with morphologic and molecular subtypes
Authors: Paietta E. , Goloubeva O. , Neuberg D. , Bennett J. M. , Gallagher R. , Racevskis J. , Dewald G. , Wiernik P. H. , Tallman M. S. 
Published: April 2004

AbstractBackgroundThe availability of genotype‐specific therapy for PML/RARαpos acute promyelocytic leukemia (APL) requires that this disease be precisely diagnosed. Immunophenotypic characteristics heretofore proclaimed as reliably characterizing APL (HLA‐DRlow, CD34low, P‐glycoproteinlow myeloid phenotype) do not differentiate from APL‐like immune profiles unassociated with the PML/RARα fusion transcript.MethodsTo establish a surrogate marker profile for APL, we explored 19 potentially predictive markers compared with differentiated acute myeloid leukemia using the classification tree approach with recursive partitioning.ResultsIn a test group of 58 APL patients, the most predictive immune profile was HLA‐DRlow, CD11alow (αL subunit of the leukocyte integrin LFA‐1), CD18low (β2 subunit of LFA‐1). APL cells always expressed CD117 (c‐kit) but lacked the progenitor antigen CD133 and the more mature myeloid antigen, CD11b (αM leukocyte integrin). This antigen pattern was validated in 90 additional APL patients. M3v APLs (n = 30) had more leukemic promyelocytes expressing the T‐cell antigen, CD2 (P < 0.0001) or the stem cell marker, CD34 (P = 0.0003) and demonstrated higher fluorescence intensity for the binding of antibody to the common leukocyte antigen, CD45 (P = 0.0008) than M3 (n = 102). S‐form APL (n = 45) had a higher percent of cells expressing CD2 or CD34 (P < 0.0001 for both) or the neural cell adhesion molecule CD56 (P = 0.001) than L‐form APL (n = 66).ConclusionsPML/RARαpos APL cells typically lack leukocyte integrins. HLA‐DRlow, CD11alow, CD18low is a reliable surrogate antigen expression profile for PML/RARαpos APL, irrespective of morphology and transcript isoform. © 2004 Wiley‐Liss, Inc.
A flow cytometric assay for simultaneous assessment of drug efflux, proliferation, and apoptosis
Authors: Barbier M. , Gray B. D. , Muirhead K. A. , Ronot X. , Boutonnat J. 
Published: April 2004

AbstractBackgroundProliferative status and multidrug resistance play a key role in determining cell response to chemotherapy. There is a need to develop multiple labeling method that allows simultaneous assessment of multidrug resistant (MDR) phenotype, proliferative status, apoptosis related changes in mitochondrial potential, in chemosensitive and chemoresistant tumor cell populations.MethodsA three‐color labeling was performed using Hoechst 33342 (DNA), JC1 (mitochondrial potential), and a far red fluorescent membrane intercalating dye: PTIR271 (proliferation).ResultsCombined staining of DNA and mitochondrial potential allows identification of subpopulations expressing and MDR phenotype mediated by P‐glycoprotein (Pgp), and, in Pgp negative subpopulations, identification of apoptotic cells and evaluation of cell cycle status in viable cells. Addition of a far red fluorescent membrane intercalating dye, PTIR271, allows simultaneous monitoring of cell division status by dye dilution in both drug sensitive and drug resistant populations.ConclusionThis triple labeling is an interesting method to study the proliferation status of drug sensitivity and drug resistance in viable tumor cells. © 2004 Wiley‐Liss, Inc.
The Reaction of μ‐η2:η2‐Peroxo‐ and Bis(μ‐oxo)dicopper Complexes with Flavonol
Authors: Kaizer József , Pap József , Speier Gábor , Párkányi László 
Published: April 2004

AbstractThe [Cu2(μ‐O)2]2+ and [Cu2(μ‐η2:η2‐O)2]2+ motifs with coordinated N,N,N‐tribenzyl‐1,4,7‐triazacyclononane and N,N,N‐triisopropyl‐1,4,7‐triazacyclononane auxiliary ligands in their reaction with flavonol do not lead to ring scission products of the heterocycle, but the formation of the corresponding (flavonolato)copper(II) complexes [Cu(fla)(Bz‐TAC)]ClO4 and [Cu(fla)(iPr‐TAC)]ClO4. The subsequent oxygenolysis of the coordinated flavonolate ligand leads to O‐benzoylsalicylate at elevated temperature, resulting in the enzyme mimicking products [Cu(O‐bs)(Bz‐TAC)]ClO4, [Cu(O‐bs)(iPr‐TAC)]ClO4) as well as carbon monoxide. The X‐ray structures of [Cu(fla)(Bz‐TAC)]ClO4, [Cu(O‐bs)(Bz‐TAC)]ClO4, and [Cu(O‐bs)(iPr‐TAC)]ClO4) are presented. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Supramolecular Structures in [Ag(dppf)] Complexes [dppf = 1,1′‐Bis(diphenylphosphanyl)ferrocene] Stabilized by Coordinatively Versatile Trifluoroacetate (TFA) Ligands
Authors: Lu Xiu Lian , Leong Weng Kee , Goh Lai Yoong , Hor Andy T. S. 
Published: April 2004

AbstractThe interaction of silver(I) trifluoroacetate and dppf in different molar equivalents has led to the isolation of dinuclear complexes [Ag2(μ‐O2CCF3)2(μ‐dppf)] (1) and [Ag2(η1‐O2CCF3)2(dppf)2] (2). Treatment of 1 with excess dppf gave a coordination polymeric compound [Ag(η2‐O2CCF3)(dppf)]n (3). Reaction of 1 with PMe2Ph in MeOH in the presence of NH4PF6 led to displacement of trifluoroacetate, forming the mononuclear compound [Ag(PMe2Ph)2(η2‐dppf)]PF6 (4). All compounds have been characterized by microanalytical and spectroscopic analyses [IR, MS and NMR (1H, 19F and 31P{1H})] as well as X‐ray diffraction studies. Molecular structures of the solvates of 1, viz. 1A (1·0.5THF) and 1B (1·0.5CH2Cl2), 2 and 3 show that they contain trifluoroacetate in bridging, monodentate and bidentate bonding modes, respectively, with dppf as a bridging co‐ligand. Compound 3 is an infinite linear [−dppf−Ag−dppf−Ag−dppf−Ag−]n coordination polymer. Interestingly, 1A and 1B form two different supramolecular network structures through C−H···F and C−H···O hydrogen‐bonding interactions. Such secondary bonding interactions also lead to the formation of a 3D supramolecular structure in 3. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Complexation Properties of Ethylenediaminetetramethylenephosphonic Acid (EDTMP) with AlIII and VIVO
Authors: Di Marco Valerio , Kilyen Melinda , Jakusch Tamás , Forgó Péter , Dombi György , Kiss Tamás 
Published: April 2004

AbstractThe complexation properties (including stoichiometries and stability constants of the complexes formed) of ethylenediaminetetramethylenephosphonic acid with AlIII and VIVO were studied in aqueous solution at an ionic strength of 0.2 M KCl, at 25 °C by means of pH potentiometry. For AlIII both mononuclear (AlLHn) and dinuclear (Al2LHn) species were found in solution, whereas for VIVO only mononuclear complexes were detected. For each metal ion, a solid complex was isolated at acidic pH and was characterized stoichiometrically. 1H and 31P NMR (for AlIII), UV/Vis and EPR (for VIVO) spectra were used to confirm the potentiometric results and to suggest the most probable binding mode of the complexes formed in solution. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)