bluuebunny/crossref_metadata_2025_split huggingface dataset:
General then Personal: Decoupling and Pre-training for Personalized Headline Generation
Authors: Song Yun-Zhu , Chen Yi-Syuan , Wang Lu , Shuai Hong-Han 
Published: December 2023

Abstract
Personalized Headline Generation aims to generate unique headlines tailored to users’ browsing history. In this task, understanding user preferences from click history and incorporating them into headline generation pose challenges. Existing approaches typically rely on predefined styles as control codes, but personal style lacks explicit definition or enumeration, making it difficult to leverage traditional techniques. To tackle these challenges, we propose General Then Personal (GTP), a novel framework comprising user modeling, headline generation, and customization. We train the framework using tailored designs that emphasize two central ideas: (a) task decoupling and (b) model pre-training. With the decoupling mechanism separating the task into generation and customization, two mechanisms, i.e., information self-boosting and mask user modeling, are further introduced to facilitate the training and text control. Additionally, we introduce a new evaluation metric to address existing limitations. Extensive experiments conducted on the PENS dataset, considering both zero-shot and few-shot scenarios, demonstrate that GTP outperforms state-of-the-art methods. Furthermore, ablation studies and analysis emphasize the significance of decoupling and pre-training. Finally, the human evaluation validates the effectiveness of our approaches.1
From Stone Canal to Orchid Terrace: Libraries and Archives in the Two Han Capitals
Authors: Waring Luke 
Published: December 2023

Abstract
Recent scholarship has advanced our understanding of the Han dynasty’s most important textual repositories, including the distinctions between libraries and archives and the roles they played in early manuscript culture. There is no comprehensive survey in English, however, of the main facilities where different manuscripts were stored in the two Han capitals, Chang’an and Luoyang. This article seeks answers to key questions: Where were these facilities located? Who worked there and how was one appointed? What kinds of activities took place in them? I confirm the findings of scholars who have shown that there is scant evidence for editing or scholastic activity in the main textual repositories before late Western Han, and that even after Emperor Cheng’s reign, textual production, curation, and instruction were distributed between multiple centers that were often in competition with one another.
A new species of the genus Bathypalaemonella Balss, 1914 (Caridea, Bathypalaemonellidae) from a seamount in the South China Sea
Authors: Wang Yanrong , Sha Zhongli 
Published: December 2023

Abstract
A new species of deep-sea shrimp, Bathypalaemonella liui sp. nov., is described from the seamount of the South China Sea at a depth of 759–1117 m. Bathypalaemonella liui sp. nov. is most similar to B. hayashi Komai, 1995 and B. serratipalma Pequegnat, 1970 for the flexor margin of the major second pereopod bearing a row of tubercles. Important morphological characters which differentiate the present new species from B. hayashi and B. serratipalma are the length of the rostrum, which is far exceeding the scaphocerite, and the dactylus of the posterior three pereopods, which only bear one pair of accessory spines. Moreover, the genetic divergences of the COI and 16S rRNA genes from these two congeners analysed, clearly support the new taxon.
Redescription of two known species of Irodes Wilson, 1911 and description of Parairodes himeji gen. et sp. nov. (Copepoda, Cyclopoida, Taeniacanthidae), parasitic on Japanese goatfishes (Actinopterygii)
Authors: Izawa Kunihiko 
Published: December 2023

Abstract
Irodes kuwaitensis Ho, Kim & Sey, 1999 and I. parupenei Ho & Lin, 2007 are redescribed based on specimens of both sexes and juveniles, recovered from the bucco-branchial cavity and the nasal cavity of the blackspot goatfish, Parupeneus spilurus (Bleeker, 1854), and Parairodes himeji gen. et sp. nov. is described on the basis of specimens of the female, recovered from under the scales of the Japanese goatfish, Upeneus japonicus (Houttuyn, 1782).
Concept of Due Care in Medical Law in a Comparative Perspective
Authors: Borysiak Witold 
Published: December 2023

Abstract
In many European legal systems, the provisions of medical legislative acts impose directly on healthcare professionals an obligation to act with due care. This imperative may be considered a basic principle of practising all medical professions, and even a generally accepted principle of medical law. Due care is the manner of conduct by medical professionals that meets the requirements contained in an objective and external standard of conduct created for each specific obligational relationship. Despite the differences between European legal systems, from a comparative perspective it is possible to notice similar factors taken into account when determining the standards of due care in medicine. This is because the conduct of medical professionals is largely determined by actual state of medical knowledge, medical standards and deontological codes relating to all medical professional activities. The aim of the article is to discuss in detail these issues in comparative perspective.
Modelling Between Digital and Humanities
Authors: Ciula Arianna , Eide Øyvind , Marras Cristina , Sahle Patrick 
Published: December 2023

This volume presents an exploration of Digital Humanities (DH), a field focused on the reciprocal transformation of digital technologies and humanities scholarship. Central to DH research is the practice of modelling, which involves translating intricate knowledge systems into computational models. This book addresses a fundamental query: How can an effective language be developed to conceptualize and guide modelling in DH?
Modelling, with its historical roots, carries multifaceted meanings influenced by various disciplinary contexts. Modelling Between Digital and Humanities innovatively connects DH with the historical tradition of model-based thinking in the humanities, cultural studies, and the sciences. It endeavors to reshape interpretative frameworks by contextualizing DH's modelling practices within a broader conceptual landscape.
Through an exploration of digital, visual and data models, the book asserts that DH holds the potential to be a cornerstone of a novel cultural literacy paradigm. By probing the interplay between technology and thought, the book ultimately positions DH as a catalyst for transformative cultural insights.
What Aspect of Model Performance is the Most Relevant to Skillful Future Projection on a Regional Scale?
Authors: Li Tong , Zhang Xuebin , Jiang Zhihong 
Published: December 2023

Abstract
Weighting models according to their performance has been used to produce multimodel climate change projections. But the added value of model weighting for future projection is not always examined. Here we apply an imperfect model framework to evaluate the added value of model weighting in projecting summer temperature changes over China. Members of large-ensemble simulations by three climate models of different climate sensitivities are used as pseudo-observations for the past and the future. Performance of the models participating in the phase 6 of the Coupled Model Intercomparison Project (CMIP6) are evaluated against the pseudo-observations based on simulated historical climatology and trends in global, regional, and local temperatures to determine the model weights for future projection. The weighted projections are then compared with the pseudo-observations in the future period. We find that regional trend as a metric of model performance yields generally better skill for future projection, while past climatology as performance metric does not lead to a significant improvement to projection. Trend at the grid-box scale is also not a good performance indicator as small-scale trend is highly uncertain. For the model weighting to be effective, the metric for evaluating the model’s performance must be relatable to future changes, with the response signal separable from internal variability. Projected summer warming based on model weighting is similar to that of unweighted projection but the 5th–95th-percentile uncertainty range of the weighted projection is 38% smaller with the reduction mainly in the upper bound, with the largest reduction appearing in southeast China.
Heating and cooling supply estimation to control buildings temperature using resistor-capacitor thermal model, unscented kalman filter, and nonlinear least square method
Authors: Zamani Vahid , Abtahi Shaghayegh , Li Yong , Chen Yuxiang 
Published: December 2023

Buildings can have varying heating and cooling set points to take advantage of favorable environmental conditions and low time-of-use rates. To optimize temperature scheduling and energy planning, building energy managements need reliable building thermal models and efficient estimation methods to accurately estimate space heating and cooling supply (or power demand) over a certain period (e.g., 24 h). This accurate estimation capability is vital for performing temperature control strategies. Therefore, the present study used resistor-capacitor (RC) models and unscented Kalman filter (UKF) integrated with nonlinear least square (NLS) to develop a method for precisely estimating heating and cooling supply to control zone temperature. To evaluate the capability of the method, two case studies are conducted. The first case study involves a made-up simple RC model, while the second case study uses monitored data from a single detached house in different scenarios. The capability of the method is evaluated by applying the estimated heating and cooling supply to the RC thermal model and simulated zone temperatures. Then, assess whether the controlled zone’s temperature meets the expected temperature or not. The performance evaluation shows that the developed method can accurately estimate the heating and cooling supply, validating its applicability to temperature control objectives.Practical ApplicationThis research provides a valuable contribution to modern building industry professionals by offering a precise method for estimating heating and cooling supply for temperature control in buildings. By equipping practitioners with an effective tool to optimize energy management, this study addresses a critical aspect of building performance. The practical case studies demonstrate the versatility and applicability of this approach in real-world scenarios. In a world increasingly prioritizing energy efficiency and sustainability, this research empowers professionals to make informed decisions, enhance building performance, and contribute to a greener and more sustainable future, all within a concise and actionable framework.
Trends in Dietary Micronutrient Adequacy in Young Adults Over the Latest 25 Years in Japan
Authors: Kobayashi Kenichiro , Torii Takashi , Maihara Toshiro 
Published: December 2023

Background: It has been assumed that economically developed countries are well nourished compared to developing countries, but little is known about how economic status affects dietary micronutrient intake in the future childbearing generation. Objective: We analyzed the trend of dietary micronutrient adequacy in young adults in Japan, as one of the representative countries with advanced dietary habits and economic progress. Methods: We conducted a retrospective analysis using 2 web-accessible databases, namely the Japanese National Health and Nutrition Survey and the World Development Indicators. Results: Japan has been facing a progressive insufficiency of dietary vitamins A and C and iron, especially among young adults, over the past 25 years. The hidden progression of silent malnutrition has become more apparent since the 2010s, coinciding with a series of economic recessions and natural disasters. Conclusions: Given that parental dietary habits play a critical role in ensuring a balanced diet for their children, our findings underscore the importance of proactive nutrition counseling and education, especially for young adults of childbearing age who have been identified as vulnerable to micronutrient deficiencies. In line with this policy, we would like to suggest the use of digital transformation platforms as a potential solution in the future, especially for the digital native population.
Evaluation of Long-Term Outcomes of Transverse Facial Cleft Repair
Authors: Kim Ju Hee , Lim So Young 
Published: December 2023

Objective To evaluate the long-term outcomes of linear commissuroplasty and linear skin closure with a focus on commissural migration. Design Retrospective study. Patients Individuals who underwent transverse facial cleft repair at a single institution between 2004 and 2021. Interventions The disrupted orbicularis oris muscle was reoriented and sutured. A simple linear commissuroplasty technique was used, and the cheek skin was closed linearly without Z-plasty. Main outcome measures The distances from Cupid's bow peak to the oral commissure were measured bilaterally, and the difference between the normal and cleft sides was obtained. Finally, its proportional value as a percentage of the total lip length was calculated from short- and long-term follow-up photographs. Cheek scarring and its effects on melolabial fold breakage were evaluated. Results Of the 18 patients who underwent transverse facial cleft repair, 12 were included in this study. The mean follow-up period based on medical photographs was 1773.5 days. The average proportional difference was 4.6%, demonstrating no observable commissural migration. There were no consistent trends in the direction of migration, either on the cleft or normal side. In patients with a transverse cleft crossing the melolabial fold, the folds appeared broken before and after the cleft repair surgery. Conclusions No significant long-term commissural migration was observed after transverse facial cleft repair with simple linear commissuroplasty and linear skin closure. Deliberate positioning of the new oral commissure, proper myoplasty, and meticulous skin closure with minimal scar burden can be considered key procedures for successful transverse cleft repair.
The Good and the Bad of SHROOM3 in Kidney Development and Disease: A Narrative Review
Authors: Paul Amy , Lawlor Allison , Cunanan Kristina , Gaheer Pukhraj S. , Kalra Aditya , Napoleone Melody , Lanktree Matthew B. , Bridgewater Darren 
Published: December 2023

Purpose of review: Multiple large-scale genome-wide association meta-analyses studies have reliably identified an association between genetic variants within the SHROOM3 gene and chronic kidney disease. This association extends to alterations in known markers of kidney disease including baseline estimated glomerular filtration rate, urinary albumin-to-creatinine ratio, and blood urea nitrogen. Yet, an understanding of the molecular mechanisms behind the association of SHROOM3 and kidney disease remains poorly communicated. We conducted a narrative review to summarize the current state of literature regarding the genetic and molecular relationships between SHROOM3 and kidney development and disease. Sources of information: PubMed, PubMed Central, SCOPUS, and Web of Science databases, as well as review of references from relevant studies and independent Google Scholar searches to fill gaps in knowledge. Methods: A comprehensive narrative review was conducted to explore the molecular mechanisms underlying SHROOM3 and kidney development, function, and disease. Key findings: SHROOM3 is a unique protein, as it is the only member of the SHROOM group of proteins that regulates actin dynamics through apical constriction and apicobasal cell elongation. It holds a dichotomous role in the kidney, as subtle alterations in SHROOM3 expression and function can be both pathological and protective toward kidney disease. Genome-wide association studies have identified genetic variants near the transcription start site of the SHROOM3 gene associated with chronic kidney disease. SHROOM3 also appears to protect the glomerular structure and function in conditions such as focal segmental glomerulosclerosis. However, little is known about the exact mechanisms by which this protection occurs, which is why SHROOM3 binding partners remain an opportunity for further investigation. Limitations: Our search was limited to English articles. No structured assessment of study quality was performed, and selection bias of included articles may have occurred. As we discuss future directions and opportunities, this narrative review reflects the academic views of the authors.
A p53 score derived from TP53 CRISPR/Cas9 HMCLs predicts survival and reveals a major role of BAX in the response to BH3 mimetics
Authors: Durand Romane , Descamps Géraldine , Bellanger Céline , Dousset Christelle , Maïga Sophie , Alberge Jean-Baptiste , Derrien Jennifer , Cruard Jonathan , Minvielle Stéphane , Lilli Nicoletta Libera , Godon Catherine , Le Bris Yannick , Tessoulin Benoit , Amiot Martine , Gomez-Bougie Patricia , Touzeau Cyrille , Moreau Philippe , Chiron David , Moreau-Aubry Agnès , Pellat-Deceunynck Catherine 
Published: December 2023

Abstract
To establish a strict p53-dependent gene-expression profile, TP53−/− clones were derived from TP53+/+ and TP53−/mut t(4;14) human myeloma cell lines (HMCLs) using CRISPR/Cas9 technology. From the 17 dysregulated genes shared between the TP53−/− clones from TP53+/+ HMCLs, we established a functional p53 score, involving 13 genes specifically downregulated upon p53 silencing. This functional score segregated clones and myeloma cell lines as well as other cancer cell lines according to their TP53 status. The score efficiently identified samples from patients with myeloma with biallelic TP53 inactivation and was predictive of overall survival in Multiple Myeloma Research Foundation–coMMpass and CASSIOPEA cohorts. At the functional level, we showed that among the 13 genes, p53-regulated BAX expression correlated with and directly affected the MCL1 BH3 mimetic S63845 sensitivity of myeloma cells by decreasing MCL1-BAX complexes. However, resistance to S63845 was overcome by combining MCL1 and BCL2 BH3 mimetics, which displayed synergistic efficacy. The combination of BH3 mimetics was effective in 97% of patient samples with or without del17p. Nevertheless, single-cell RNA sequencing analysis showed that myeloma cells surviving the combination had lower p53 score, showing that myeloma cells with higher p53 score were more sensitive to BH3 mimetics. Taken together, we established a functional p53 score that identifies myeloma cells with biallelic TP53 invalidation, demonstrated that p53-regulated BAX is critical for optimal cell response to BH3 mimetics, and showed that MCL1 and BCL2 BH3 mimetics in combination may be of greater effectiveness for patients with biallelic TP53 invalidation, for whom there is still an unmet medical need.
Complete or partial loss of the Y chromosome in an unselected cohort of 865 non-vasectomized, azoospermic men
Authors: Fedder J , Fagerberg C , Jørgensen MW , Gravholt CH , Berglund A , Knudsen UB , Skakkebæk A 
Published: December 2023

Abstract
Background
Structural abnormalities as well as minor variations of the Y chromosome may cause disorders of sex differentiation or, more frequently, azoospermia. This study aimed to determine the prevalence of loss of Y chromosome material within the spectrum ranging from small microdeletions in the azoospermia factor region (AZF) to complete loss of the Y chromosome in azoospermic men.

Results
Eleven of 865 azoospermic men (1.3%) collected from 1997 to 2022 were found to have a karyotype including a 45,X cell line. Two had a pure 45,X karyotype and nine had a 45,X/46,XY mosaic karyotype. The AZF region, or part of it, was deleted in eight of the nine men with a structural abnormal Y-chromosome. Seven men had a karyotype with a structural abnormal Y chromosome in a non-mosaic form. In addition, Y chromosome microdeletions were found in 34 men with a structural normal Y chromosome. No congenital malformations were detected by echocardiography and ultrasonography of the kidneys of the 11 men with a 45,X mosaic or non-mosaic cell line.

Conclusions
In men with azoospermia, Y chromosome loss ranging from small microdeletions to complete loss of the Y chromosome was found in 6.1% (53/865). Partial AZFb microdeletions may give a milder testicular phenotype compared to complete AZFb microdeletions.
Predicting potential microbe-disease associations based on auto-encoder and graph convolution network
Authors: Lu Shanghui , Liang Yong , Li Le , Miao Rui , Liao Shuilin , Zou Yongfu , Yang Chengjun , Ouyang Dong 
Published: December 2023

AbstractThe increasing body of research has consistently demonstrated the intricate correlation between the human microbiome and human well-being. Microbes can impact the efficacy and toxicity of drugs through various pathways, as well as influence the occurrence and metastasis of tumors. In clinical practice, it is crucial to elucidate the association between microbes and diseases. Although traditional biological experiments accurately identify this association, they are time-consuming, expensive, and susceptible to experimental conditions. Consequently, conducting extensive biological experiments to screen potential microbe-disease associations becomes challenging. The computational methods can solve the above problems well, but the previous computational methods still have the problems of low utilization of node features and the prediction accuracy needs to be improved. To address this issue, we propose the DAEGCNDF model predicting potential associations between microbes and diseases. Our model calculates four similar features for each microbe and disease. These features are fused to obtain a comprehensive feature matrix representing microbes and diseases. Our model first uses the graph convolutional network module to extract low-rank features with graph information of microbes and diseases, and then uses a deep sparse Auto-Encoder to extract high-rank features of microbe-disease pairs, after which the low-rank and high-rank features are spliced to improve the utilization of node features. Finally, Deep Forest was used for microbe-disease potential relationship prediction. The experimental results show that combining low-rank and high-rank features helps to improve the model performance and Deep Forest has better classification performance than the baseline model.