bluuebunny/crossref_metadata_2025_split huggingface dataset:
Absorption Spectra of p-Nitroaniline Derivatives: Charge Transfer Effects and the Role of Substituents
Authors: Máximo-Canadas Matheus , Borges Itamar 
Published: November 2023

Abstract
Context
Push-pull compounds are model systems and have numerous applications. By changing their substituents, properties are modified and new molecules for different applications can be designed. The work investigates the gas phase electronic absorption spectra of fifteen derivatives of p–nitroaniline (pNA) using theoretical methods. This molecule has applications in pharmaceuticals, azo dyes, corrosion inhibitors, and optoelectronics. Both electron-donor and electron-withdrawing groups were investigated. Overall, electron-donors redshift the absorption spectrum and reduce the HOMO-LUMO energy gap. Conversely, electron-withdrawing groups blueshift the spectrum and increase the energy gap. A comprehensive charge transfer (CT) analysis of the main transition of all systems was also carried out. We found that donors slightly enhance the CT character of the unsubstituted pNA, whereas acceptors decrease it, leading to increased local excitations within the aromatic ring. The overall CT variation is not large, except for pNA–SO2H, which considerably decreases the total CT value. It was found that the strong electron donors pNA–OH, pNA–OCH3, and pNA–NH2, which have small HOMO-LUMO energy gaps, have potential for optoelectronic applications.
Methods
We investigated theoretically employing the second-order algebraic diagrammatic construction (ADC(2)) ab initio wave function the gas phase electronic absorption spectra of fifteen derivatives of p–nitroaniline (pNA). The substituents considered in this investigation included both electron-donor (C6H5, CCH, CH3, NH2, OCH3, and OH,) and electron-withdrawing (Br, CCl3, CF3, Cl, CN, COOH, F, NO2, and SO2H) substituents. Employing machine-learning-derived Hammett's constants σm, σm0, σR, and σI, correlations between substituents and electronic properties were obtained.
Decomposition of the changes in household disposable income distribution in China
Authors: Gong Chen , Sologon Denisa , Nimeh Zina , O'Donoghue Cathal 
Published: November 2023

Abstract
Studies have shown that the previously growing inequality in China has stabilized and even declined since 2008 (Kanbur et al., 2021), nevertheless, the drivers of the latest transformation in income inequality remain to be unraveled. We address this research gap by examining the changes in the distribution of household disposable income and its drivers in China from 2010 to 2016. We apply the distributional decomposition method proposed by Bourguignon et al. (2008) and Sologon et al. (2021), and quantify the contribution of all factors into four general dimensions, (1) demographic composition, (2) labor market structure, (3) price and return, and (4) governmental transfers.
This study considers not only the individual labor income as with existing literature, but also models other family incomes and social transfers to reflect the real economic conditions more accurately. The decomposition results show that all four factors contribute positively to the decline in income inequality during the period studied. The changes in urban labor market structure, specifically the general forms of employment, occupational and industrial structure, have been contributing as inequality augmenting factors.
JEL Classification: D31, D63, H55, J18, O15
Reinforcement learning in biological systems for adaptive regulation
Authors: Yamaguchi Tomoyuki 
Published: November 2023

Abstract
The adaptive control of complex biological systems remains unclear despite extensive research on their regulatory networks. We recently reported that epigenetic regulation of gene expression may be a learning process, in which amplification-and-decay cycles optimize expression patterns while basically maintaining current patterns. Here, we show that various biological processes, such as intestinal immunity, population dynamics, chemotaxis, and self-organization, are also characterized as reinforcement learning (RL) processes. An appropriate population balance is established autonomously through symmetric competitive amplification and decay, which is a biologically plausible RL process. Monte Carlo simulations of predator-prey numbers show that population dynamics based on this RL process enable the sustainability of predators and reproduce fluctuations with a phase delay when humans hunt prey more preferentially than predators. Another example is a random walk controlling step-length (s-rw), which allows the agent to approach the target position with a Levy walk trajectory. In addition, shortcut paths in a maze are autonomously generated by s-rw using a moving-direction policy or bias, which is optimized through another RL on a longer timescale. Furthermore, by applying s-rw to reaction-diffusion theory, Turing patterns can be self-organized. The RL process, expressed by a common mathematical equation, enables the adaptability of biological systems.
LSDNet: A Lightweight Ship Detection Network with Improved YOLOv7
Authors: Lang Cui , Yu Xiaoyan , Rong Xianwei 
Published: November 2023

Abstract
Accurate ship detection is critical for maritime transportation security. Current deep learning-based object detection algorithms have made marked progress in detection accuracy. However, these models are too heavy to be applied in mobile or embedded devices with limited resources. Thus, this paper proposes a lightweight convolutional neural network shortened as LSDNet for mobile ship detection. In the proposed model, we introduce Partial Convolution (PConv) into YOLOv7-tiny to reduce its parameter and computational complexity. Meanwhile, GhostConv is introduced to further achieve lightweight structure and improve detection performance. In addition, we have replaced Mosaic-4 data augmentation with Mosaic-9 to enhance the robustness of the model. We compared the proposed LSDNet with other approaches on a publicly available ship dataset, SeaShips7000. The experimental results show that LSDNet achieves higher accuracy than other models with less computational cost and parameters. The test results also suggest that the proposed model can meet the requirements of real-time applications.
Construct validity and Reliability of Amharic version of DASS-21 scale among Ethiopian Defense University College of Health Science Students
Authors: Tsegaye Bitew Sintayehu , Asemu Meseret Molla , Hailu Habtamu Belay 
Published: November 2023

Abstract
Background
DASS-21 is the common and widely used tool for assessing depression, anxiety and stress. However, its validity and Reliability in Ethiopian Amharic language is not assessed.
Objective
To translate the DASS-21 and assess its validity and reliability among Ethiopian Defense University college of health science students in Bishoftu, Ethiopia.
Method
An anonymous, self-administered questionnaire was used to collect the data on 435 undergraduate health science students. Confirmatory factor analyses were employed to assess the factor structure and construct validity of Amharic version of the DASS-21. Cronbach alpha coefficient and corrected item total correlation was calculated to assess the internal consistency of Amharic version of DASS-21.
Result
Confirmatory factor analysis indicates a good model fit of the three correlated factors (Comparative fit index (CFI) = 0.92 with root mean square error of approximation (RMSEA) = 0.059[0.063–0.066] and standardize root mean residual SRMR = 0.045). The internal consistency of overall DASS-21 and each sub scale were in acceptable range (0.82, 0.77and 0.77) respectively.
Conclusion
Amharic version of DASS-21 was found to be a valid and reliable instrument to measure the mental problem especially, Depression, Anxiety and Stress among university students.
Validation of Microsatellite Markers for Sex Determination in Date Palm (Phoenix dactylifera) cv. Madjoole
Authors: Salameh Aziz , Hamdan Yamen , Aslan Khaled 
Published: November 2023

Abstract
The date palm (Phoenix dactylifera) is a dioecious plant, and its sexual characteristics remain indiscernible until it reaches the reproductive stage, typically between 4 to 5 years of age. The cultivar C. madjoole is widely grown in Palestine and neighboring regions. Early identification of male and female seedlings could significantly benefit date palm cultivation and breeding efforts. This study aimed to confirm the effectiveness of microsatellite markers in distinguishing between male and female date palms within the cv. Madjoole variety. Out of eight microsatellite primers used, four markers were able to determine the sex of the date palm tree. mPdCIR010 produced a male specific band (325pb) while mPdCIR093 produced a female specific band (335 pb); on the other side, mPdCIR015 and mPdCIR078 produced unique female bands (160 and 128 pb), respectively. A total of 15 loci were identified, averaging 2.1 loci per primer. SSR markers were able to provide a reliable technique for sex determination in date palm (cv. Madjoole) at an early stage. The utilization of SSR markers will not only advance but also facilitate the establishment of commercial date palm cultivation through seed propagation in Palestine and the surrounding region. Consequently, the available date palm genetic resources could be expanded, leading to enhanced national breeding programs. The ability to use mPdCIR093 as a female specific marker is approved for cv. Madjoole but needs to be validated with other date palm cultivars.
Evolution of radiation-induced temporal lobe injury after intensity-modulated radiation therapy in nasopharyngeal carcinoma: a large cohort retrospective study
Authors: Hou Jing , He Yun , Li Handong , Ai Zhaodong , Lu Qiang , Zeng Biao , Xie Chuanmiao , Yu Xiaoping 
Published: November 2023

Abstract
Background
Previous studies have demonstrated conflicting findings regarding the initial MRI patterns of radiotherapy-induced temporal lobe injury (RTLI) and the evolution of different RTLI patterns. The aim of this study was to evaluate the initial MRI pattern and evolution of RTLI in patients with nasopharyngeal carcinoma (NPC) by means of a large cohort study.
Methods
Data of patients with RTLI were retrospectively collected from two hospitals between January 2011 and December 2021. The injured lobes were categorized into three patterns based on initial MRI patterns: isolated white matter lesions (WMLs), isolated contrast-enhanced lesions (CELs), and combined WMLs and CELs. The latency period, MRI appearances, and temporal changes in WMLs and CELs were evaluated.
Results
A total of 913 RTLI patients with 1092 injured lobes were included in this study. The numbers of isolated WMLs, isolated CELs, and combined WMLs and CELs identified at the first MRI detection were 7(0.6%), 172(15.8%), and 913(83.6%), respectively. The evolution of bilateral RTLI was different in the same patient, and that of unilateral RTLI combined with WMLs and CELs also may occur asynchronously. The time intervals from the initial MRI detection of isolated WMLs, isolated CELs, combined WMLs and CELs to the last negative MRI scan were 8.6, 8.9 and 11.0 months, respectively. A significant difference was observed in the time intervals between the three patterns (H = 14.287, P = 0.001). And the time interval was identified as an independent factor influencing the initial MRI pattern of RTLI after Poisson regression (P = 0.002).
Conclusion
Both WMLs and CELs could be the initial and only MRI abnormalities in patients with RTLI. This study is of great significance in accurately diagnosing RTLI early and providing timely treatment options. Additionally, it provides clinical evidence for guidelines on NPC, emphasizing the importance of regular follow-up of NPC patients.
Early versus Delayed Laparoscopic Cholecystectomy for Mild Acute Biliary Pancreatitis: A Systematic Review and Meta-Analysis
Authors: Zhou Yu , Zhang Yun , Pu Feng , Kang Zhiqiang , Zhang Qiu , Zhao Tang , Xu Zihan , Zhang Xiaohong , Wang Haizhen , Yin Wenqing , Yang Hongji , Zhu Shikai 
Published: November 2023

Abstract
Background Laparoscopic cholecystectomy (LC) is widely accepted as the definitive therapeutic approach for MABP, primarily aiming to reduce recurrent biliary complications. However, the optimal timing of LC remains a matter of debate. The aim of this study was to evaluate the efficacy and safety of early laparoscopic cholecystectomy (ELC) versus delayed laparoscopic cholecystectomy (DLC) in patients with mild acute biliary pancreatitis (MABP).
Methods The PubMed, Embase, Scopus, and CENTRAL databases were systematically searched for randomized clinical trials (RCTs) comparing ELC with DLC in patients with MABP from inception to August 1, 2023. The primary outcome was recurrent biliary events. Secondary outcomes included postoperative complications, readmissions, and length of stay (LOS). The pooled risk ratio (RR) or standardized mean difference (SMD) of data was calculated using the random-effects model.
Results Fifteen RCTs with 1616 patients enrolled between 2010 and 2022 were included. High-certainty evidence from nine RCTs demonstrated a significantly lower risk of recurrent biliary events in patients who underwent ELC during the waiting time compared to DLC (RR=0.128[0.063, 0.262], P<0.001). For secondary outcomes, ELC in patients with MABP was associated with a significantly lower readmission rate (RR=0.382[0.182, 0.801], P=0.011) and shorter LOS (SMD=-2.026[-2.854, -1.198], P<0.001) than DLC. Subgroup analysis indicated that patients with ELC had a significantly lower rate of postoperative complications in accordance with the Atlanta criteria, MABP, and >4 weeks subgroup.
Conclusions ELC emerges as a generally safe and effective strategy in reducing recurrent biliary events, postoperative complications, readmission, and length of stay for patients with MABP.
Role of genome-wide association studies, polygenic risk score and AI/ML using big data for personalized treatment to the patients with cardiovascular disease
Authors: Abdelhalim Habiba , Hunter Rachel-Mae , DeGroat William , Mendhe Dinesh , Zeeshan Saman , Ahmed Zeeshan 
Published: November 2023

Tweetable abstract Role of GWAS, polygenic risk score and AI/ML using big data for personalized treatment to the patients with cardiovascular disease
Mengoptimalkan literasi masyarakat perdesaan melalui seminar pola asuh: Mendidik anak kembali ke fitrah
Authors: Agustiana Vina 
Published: November 2023

Mendidik anak bukanlah perkara yang mudah. Kesalahan yang dilakukan orang tua dalam menerapkan model pengasuhan dapat mempengaruhi perilaku anak di kemudian hari. Oleh karena itu, mempelajari prinsip-prinsip pengasuhan yang tepat untuk membentuk karakter positif pada anak-anaknya merupakan hal yang sangat penting bagi orang tua. Pola asuh yang baik dapat membantu menumbuhkan rasa peduli, jujur, mandiri, dan gembira pada anak. Pola asuh yang baik juga dapat menunjang kecerdasan dan melindungi anak dari kecemasan, depresi, pergaulan bebas, penyalahgunaan alkohol dan narkoba. Melalui kegiatan pengabdian kepada Masyarakat, penulis mengadakan kegiatan seminar pola asuh dengan tema Mendidik Anak Kembali ke Fitrah dengan tujuan agar memperluas wawasan peserta serta mengubah cara pandang peserta dalam pola asuh anak. Kegiatan ini melibatkan 37 wali murid di salah satu sekolah taman kanak-kanak di Desa Ciwaru Kecamatan Ciwaru Kabupaten Kuningan. Pemateri yang di undang ialah salah satu praktisi dalam bidang pola asuh anak. Berdasarkan hasil wawancara dengan peserta, ditemukan bahwa: (a) tidak adanya kerjasama yang baik antara ayah dan ibu dalam mendidik anak serta dalam berbagi kewajiban rumah tangga; (b) adanya hukuman verbal dan non-verba, seperti memaki, mencubit bahkan mengunci anak di kamar mandi; (c) anak diasuh oleh orang lain (nenek atau kerabat dekat) dikarenakan orangtua yang bercerai. Adapun setelah adanya kegiatan seminar ini, terdapat kesimpulan bahwa: (a) harus adanya aturan yang diterapkan dirumah terkait kedisiplinan; (b) orangtua harus menjadi role model yang baik bagi anak; (c) adanya komunikasi yang baik antara orangtua; (d) Ketika ayah sedang menasehati anak, maka ibu tidak membela, juga sebaliknya; (e) menghindari hukuman verbal dan non verbal karena berdampak buruk bagi psikologis anak; (f) mencontoh sikap Rasulullah dalam mendidik anak.
Salivary and crevicular fluid proinflammatory cytokines and advanced glycation end products in patients with different glycemic levels undergoing fixed orthodontic treatment
Authors: Kamran Muhammad Abdullah 
Published: November 2023

ABSTRACT

Objective
To examine whether patients with different blood glycemic levels undergoing fixed orthodontic therapy demonstrate changes in the biochemical profiles of crevicular fluid and salivary advanced glycation end products (AGEs) and proinflammatory cytokine levels in comparison with nondiabetic healthy subjects.

Materials and Methods
Prediabetic subjects, subjects with type 2 diabetes mellitus (T2DM), and subjects without a diabetes mellitus diagnosis undergoing fixed orthodontic therapy with MBT prescription brackets (0.022-inch brackets and 0.019 × 0.025-inch stainless steel archwires) were included in the study. The following clinical periodontal parameters were evaluated: (1) plaque score (PS), (2) probing depth (PD), (3) bleeding on probing (BOP), and (4) clinical attachment loss. Crevicular fluid and saliva specimens were collected during regular orthodontic visits. Salivary and crevicular fluid tumor necrosis factor alpha, interleukin-6, ghrelin, resistin, AGEs, and receptor activator of nuclear factor κΒ ligand were evaluated using a human magnetic Luminex multiplex assay.

Results
BOP scores were significantly higher among T2DM subjects (19.2%) than among nondiabetic subjects (11.2%) and prediabetic subjects (15.9%). Comparable values were demonstrated by all three study groups regarding PD scores and PSs. T2DM subjects demonstrated higher scores for gingival crevicular fluid (GCF) chemokines than nondiabetic and prediabetic subjects. A statistically significant difference was found in the levels of AGEs and resistin among the three study groups. The scores revealed for the levels of GCF resistin and AGEs versus periodontal BOP demonstrated a significant positive association by the Pearson correlation test.

Conclusions
T2DM patients demonstrated significantly higher levels of GCF resistin and AGEs during fixed orthodontic therapy. Chronic hyperglycemic patients undergoing orthodontic therapy demonstrated a proinflammatory response.
Ibrahim : Dari Penjual Kopra Sampai Menjadi Pengusaha Industri Minyak kelapa Di Nagari Lareh Nan Panjang Barat, Kecamatan VII Koto Sungai Sarik, Kabupaten Padang Pariaman (1965-2000)
Authors: Khairi Syabikul , Naldi Hendra 
Published: November 2023

Penelitian ini membahas tentang biografi Ibrahim (Sibaduik), seorang pengusaha Industri Minyak Kelapa Kopra asal Lareh Nan Panjang, Kecamatan VII Koto Sungai Sarik. Penelitian ini bertujuan untuk mengetahui perjalanan karir Baduik sebagai pengusaha Industri Minyak Kopra dan dampaknya terhadap kehidupan masyarakat sekitar. Penelitian ini menggunakan metode penelitian sejarah dengan empat tahap. Tahap pertama heuristik (mengumpulkan data), tahap kedua kritik sumber (menguji keaslian informasi), tahap ketiga adalah interpretasi (menafsirkan data), dan tahap keempat adalah historiografi (tulisan). Hasil penelitian ini menjelaskan bahwa perjalanan karir Sibaduik dimulai dari menjadi seorang pembeli kelapa dan kopra dengan Bakonya di Limau Puruik selama dua tahun hingga akhirnya sukses mendirikan pabrik industri minyak kopra sendiri di rumah. Tak hanya sukses mendirikan pabrik industri minyak kopra, Sibaduik juga memanfaatkan limbah olahan minyak kopra untuk dijadikan sabun. Adanya pabrik Baduik memberikan dampak positif bagi kehidupan masyarakat sekitar dengan memberikan lapangan pekerjaan.
Nutritional and medicinal values of Mangifera indica L. fruit
Authors: Rajasekaran Anitha , Soundarapandian Sharmila 
Published: November 2023

Mangifera indica L. (Mango, Anacardiaceae) is a popular tropical evergreen tree known for its nutritional and medicinal values. It is native to India and Southeast Asia and is known as the “king of fruits” in India and the Philippines. It is considered important in Ayurveda and other systems of medicine. Mango fruit is unique in its taste, colour, aroma, and nutritional qualities. Mangoes are a rich source of polyphenols (Mangiferin, Gallotannins, Quercetin, Isoquercetin, Ellagic acid, Glucogallin, Kaempferol, Catechins, Tannins, and the unique Xanthonoid), phenolic acids (Hydroxybenzoic acids- Gallic, Vanillic, Syringic, Protocatechuic, and p-Hydroxybenzoic acids, Hydroxycinnamic acid derivatives-p-Coumaric, Chlorogenic, Ferulic, and Caffeic acids), flavonoids (β-carotene, α-carotene, β-cryptoxanthin, and Lutein), Vitamin A, Vitamin-B6 (pyridoxine), Vitamin-C, Vitamin-E, Carbohydrates, Amino acids, Organic acids, micronutrients (Potassium, Copper), fats (Omega-3 and 6 polyunsaturated fatty acids), dietary fibre and certain volatile compounds. About 25 different types of carotenoids have been isolated from the fruit pulp, which contributes to the colour of the fruit. Phytochemical and nutrient content may vary depending on the cultivar. Mangoes possess potential medicinal properties such as antioxidant, gastro-protective, anti-inflammatory, analgesic, immunomodulatory, anti-microbial, and many more. Mango fruit is an abundant source of all essential nutrients and phytochemicals; it could be ultilized as a nutritional supplement in the prevention and cure of several diseases. A comprehensive report on the nutritional and medicinal properties of fruit is presented below.
Effects of pirfenidone on scar size and ventricular remodeling after myocardial infarction: a preclinical study
Authors: Aimo Alberto , Burchielli Silvia , Barison Andrea , Aquaro Giovanni Donato , Musetti Veronica , Masotti Silvia , Pucci Angela , Modena Martina , Terlizzi Domiziana , Passino Claudio , Emdin Michele 
Published: November 2023

Background
An intense fibrotic response after myocardial infarction (MI) may lead to scar expansion and left ventricular (LV) remodeling. We investigated the effects of the antifibrotic drug pirfenidone in this setting.

Methods
Male Wistar rats were randomized to: sham procedure (n = 13), reperfused MI-induced by ligating the left anterior descending artery (LAD) for 45 min (n = 17), reperfused MI plus standard therapy (aspirin, angiotensin-converting enzyme inhibitor, beta blocker, and mineralocorticoid receptor antagonist) (n = 17), reperfused MI plus pirfenidone alone (n = 17), or reperfused MI plus standard therapy and pirfenidone (n = 17). Rats surviving MI induction underwent cardiac magnetic resonance scans after 72 h and 30 days from MI, and were sacrificed on day 31.

Results
Rats completing the whole protocol numbered 11 in the sham group, 9 in the untreated MI group, 8 in the standard treatment group, 9 in the pirfenidone alone group, and 9 in the standard treatment plus pirfenidone group. No significant differences emerged between LV volumes, ejection fraction or mass at 30 days or the differences from 72 h to 30 days. Small, nonsignificant differences between rats on pirfenidone alone vs. those on standard therapy emerged. The total extent of LV fibrosis, quantified as area and percentage of the tissue sample, did not differ significantly between rats on pirfenidone alone vs. those on standard therapy alone.

Conclusion
Pirfenidone does not have additional effects on LV remodeling or fibrosis compared with standard therapy, but its effects are similar to standard therapy alone.