bluuebunny/crossref_metadata_2025_split huggingface dataset:
Precision Therapy for Prostate Cancer: Advancements in Polymeric Nanocarrier Systems
Authors: Kumar Lalit , Rana Ritesh , Shaikh Nusrat K. , Kumar Sumit , Aggarwal Vikas , Komal Komal , Jyothiraditya Vuluchala 
Published: February 2025

Introduction:
Prostate cancer is a major worldwide health concern, and existing treatments often face
challenges such as drug resistance, systemic toxicity, and insufficient targeting. Polymeric nanocarriers are currently
employed as sophisticated tools in the field of oncology, offering the possibility to augment the administration
and efficacy of anticancer therapies. In order to effectively eradicate prostate cancer, this review delves into
the function of polymeric nanocarriers.

Methods:
Databases such as PubMed, ScienceDirect, and Google Scholar were utilized to do a comprehensive
literature assessment. For this search, we used terms like "polymeric nanocarriers," "prostate cancer," "drug delivery,"
and "nanotechnology."

Results:
Studies have shown that polymeric nanocarriers greatly improve the delivery and effectiveness of treatments
for prostate cancer. Nanocarriers enhance the solubility, stability, and bioavailability of drugs, resulting in
improved therapeutic effects. Functionalization using targeting ligands, such as folic acid and prostate-specific
membrane antigen (PSMA) antibodies, has demonstrated the ability to enhance targeted specificity, resulting in a
decrease in off-target effects and systemic toxicity. Polymeric nanocarriers facilitate precise and prolonged drug
delivery, leading to elevated drug levels in tumor tissues.

Conclusion:
Polymeric nanocarriers are a notable breakthrough in the management of prostate cancer, providing
precise medication administration, decreased toxicity, and improved therapy effectiveness. However, additional
study is necessary to enhance the design of nanocarriers, evaluate their long-term safety, and enable their use in
clinical applications. Continued interdisciplinary research and collaboration are essential for addressing current
obstacles and maximizing the promise of polymeric nanocarriers in the treatment of prostate cancer.
The Global Cosmetic Industry: Regulatory Challenges and Innovations for Ensuring Safety and Compliance
Authors: Monika . , . Pragi , Kumar Varun , . Jyoti , Sarswa Anish , . Shrikant , Malik Gaurav , Kumari Shabnam 
Published: February 2025

Abstract:
The cosmetics industry is a dynamic, ever-expanding worldwide enterprise. The need
for premium goods has led to the exponential rise of the beauty and cosmetics business in recent
years. Governments worldwide are enforcing rules to ensure the safety and effectiveness of cosmetic
products in response to the rapidly evolving sector. The global cosmetics industry is experiencing
a surge in growth, driven by a growing emphasis on wellness and self-care, despite a
minor setback during the COVID-19 pandemic. Global regulation of cosmetic products ensures
efficacy and safety, but differing policies across nations can impact industry competitiveness and
profitability. The global industry faces challenges due to differing regulatory frameworks across
markets, which are not harmonized, restricting innovation and market growth. These differences
also affect international trade and hinder the role of regulatory authorities. The European Union
(EU's) cosmetic regulatory framework provided by Regulation (EC) No. 1223/2009, ensures uniformity
across member states and adapts to technical progress. This Regulation, which took the
place of the earlier, 1976- adopted Directive 76/768/EC, was an attempt to bring regulations in
all EU member states into compliance while also keeping up with much-needed technological
advancements. Globally regulatory agencies have their own regulations to assure the safety of
cosmetics. The EU and the United States of America (USA) account for the majority of the cosmetic
market. The regulations in these regions serve as a model for the developing globe. The
article emphasizes the need for harmonization in cosmetic rules across countries, focusing on
safety, stability, and labeling.
Aerobic Stress Detection in Aquatic Environments with Water Quality Data Using Hybrid Deep Learning Based ConvRec Model
Authors: Simhadri Naidu Surapu  , Kanusu Srinivasa Rao  , V. Ratnakumari Challa  
Published: February 2025

Depletion of dissolved oxygen in the water is a serious threat to fish and other aquatic organisms, it causes aerobic stress disease in fish. Detection of aerobic stress is crucial to maintain better growth and spawning in the fishes. Recently many studies proposed deep learning-based water quality analysis techniques, but these techniques inadequate in handling the complex water quality data. Because water quality has both spatial and temporal characteristics, this makes most of the deep learning models inadequate. To handle such complex and multifaceted data we proposed ConvRec, a deep learning architecture that incorporates CNN (Convolution neural network) and LSTM (Long-short term network) structures. CNN component extracts feature in the spatial domain from the water quality data from different locations while LSTM captures temporal features hence the model can learn both spatial and temporal correlations between the movement of water quality parameters to classify the aerobic stress in aqua ponds. In this work we use the two dataset both are unlabelled collected using IoT (Internet of things) devices. To handle this data using ConvRec model, usus the fine-grained annotation of data points that have the effect of empowering the model to detect relevant traits associated with oxygen stress in fish. It can be therefore ascertained that ConvRec yields high degrees of accuracy of 99.2% and 99.65%, on the “ponds” and “waterx” datasets respectively while the past models can only 98.2% and 98.1% respectively on the same datasets. These results demonstrate that ConvRec is not only promising for estimating the health of fish during oxygen deficiency but also it can take part in reducing the negative impact of low oxygen levels in the water on fish.
A Toolkit for Developing Professional Skepticism in the Accounting Classroom
Authors: Agrawal Prerana , Birt Jacqueline , Holub Mark , van Zyl Warrick 
Published: February 2025

ABSTRACT
Professional skepticism is an important trait for the accounting profession. Research shows that it can be developed in the pre-professional phase (Martinov-Bennie, Dyball, and Tweedie 2022). In this project, we designed a toolkit comprising four case studies (Payroll, Inventory, Receivables, and Impairment) to develop skepticism in accounting students. Using “search for embedded misstatements” as a tool, we facilitate key attributes necessary to exercise skepticism, including attention to detail, search for knowledge, a questioning mindset, critical thinking, problem-solving, an awareness of bias, and the confidence to challenge and provide alternative solutions. We deliberately designed a series of cases rather than a single case to provide students with the repeated practice that is more likely to habituate their disposition to act skeptically. However, these cases can be used independently or adapted to suit different accounting units. The toolkit was well received by students and was effective in increasing their level of skepticism.
Who requires dental treatment under general anesthesia due to pain and severe dental anxiety? Findings from panoramic X-ray images and anamnesis
Authors: Aardal Vilde , Hol Caroline , Rønneberg Anne , Neupane Sudan Prasad , Willumsen Tiril 
Published: February 2025

Objective: The aims were to describe the dental status and mental and somatic health profile of patients with severe dental anxiety requiring dental treatment under general anesthesia (GA) in Rogaland County, Norway (2018–2021), and to compare patients with and without reported abuse history.
Material and methods: Dental status was assessed by panoramic X-rays. General health variables were collected from patient records. Statistical comparisons of patients with and without abuse experience by tests of association (significance level p < 0.05).
Results: 38 women and 18 men (mean ± standard deviation [SD]: 37.9 ± 9.2 years) were included; 27 reported abuse experience. Dental assessment showed 4.6 ± 3.8 missing teeth, 4.8 ± 3.0 root remnants, 5.8 ± 3.7 teeth with caries and 2.6 ± 1.9 teeth with apical periodontitis, among patients with ≥1 of the respective findings. 57.1% used analgesics due to dental pain. 55.4% had comorbid psychiatric conditions; 35.7% used psychopharmaceuticals. There were no statistical differences in dental variables but the abuse experience group had higher frequencies of comorbid psychiatric disorders (p = 0.01) and mixed somatic conditions (p = 0.03).
Conclusions: Patients with severe dental anxiety requiring dental treatment under GA have complex health problems. They need access to treatment under GA, as treatment of serious odontogenic conditions is otherwise unmanageable.
IMPLEMENTASI KEBIJAKAN PENGELOLAAN SAMPAH BERBASIS MASYARAKAT DI KELURAHAN ANTAPANI TENGAH KECAMATAN ANTAPANI KOTA BANDUNG
Authors: Mariane Ine , Rosana Gnagey Mira , Asad Mohamad Ibrahim Karali Muaddah , Hardiyanti Elsa 
Published: February 2025

Sampah di kota Bandung menjadi isu yang perlu diselesaikan bersama oleh sektor pemerintah, akademisi, hingga komunitas. Sebanyak 1.500 ton sampah dihasilkan setiap harinya di Kota Bandung atau 0,63 kg tiap orang per hari. Pandangan terhadap sampah perlu diubah dari 'permasalahan' menjadi 'potensi' melalui sistem pengelolaan sampah dari rumah yaitu dengan memisahkan sampah berdasarkan jenisnya agar sampah tidak tercampur dan memudahkan penanganan lebih lanjut melalui Bank sampah, sehingga sampah yang masuk ke TPA hanya tersisa residu saja. Tujuan penelitian menganalisis kebijakan pemerintah kota Bandung dan mengetahui Model Jejaring Kebijakan dalam upaya pengelolaan sampah berbasis masyarakat di Kelurahan Antapani Tengah Kecamatan Antapani Kota Bandung Metode yang digunakan pendekatan kualitatif melalui studi literatur dan fenomenologi. Sumber data Kepala Dinas Lingkungan Hidup dan Kebersihan , Pengelola Bank Sampah , tim peneliti. Data dikumpulkan dengan Wawancara, Observasi , dan Dokumentasi. Keabsahan dan kredibilitas data menggunakan teknik triangulasi sumber . Teknik analisis data berupa pengumpulan , reduksi , dan penyajian data , serta penarikan Kesimpulan Hasil analisis 1)standar dan sasaran kebijakan jelas 3) sikap para pelaksana baik respon maupun pemahaman belum cukup baik, 4)lingkungan ekonomi, sosial, politik belum optimal baik sumber anggaran, Sosialisasi . Faktor penghambat yaitu pimpinan kewilayahan, kurang kontrol, partisipasi warga Simpulan; Model Jejaring Kebijakan Laba-laba sangat sesuai dipakai dalam upaya pengelolaan sampah berbasis masyarakat di kelurahan Antapani Tengah kecamatan Antapani kota Bandung.
Implementación de tecnología en los procesos de orientación dentro de la orientación costarricense
Authors: Gómez-Díaz David 
Published: February 2025

Este artículo analiza el uso de tecnologías en los procesos de orientación durante 2020, un año marcado por una pandemia que impulsó una reinvención educativa basada en herramientas digitales. Con enfoque cualitativo y diseño fenomenológico, se realizaron entrevistas a 11 profesionales en orientación. La información se organizó y codificó para identificar acciones, métodos y beneficios relacionados con la incorporación tecnológica. Las intervenciones se centraron en orientación vocacional, distribución de información y creación de comunidades en línea, utilizando herramientas como WhatsApp, Teams, videos, imágenes y actividades masivas virtuales. Entre las fortalezas se destacan el aprendizaje autodidacta, la superación de desafíos y la reducción de costos. No obstante, surgieron limitaciones, como el desconocimiento tecnológico, la falta de contacto humano y la brecha digital. El propósito principal fue promover bienestar, comunicación y conexión con la población estudiantil. Si bien se reconoce el potencial de la tecnología en la orientación, se enfatiza la necesidad de evaluar la efectividad de estas estrategias. Persisten desafíos significativos, como superar la brecha digital y garantizar un equilibrio entre el uso tecnológico y el contacto humano, elementos clave para una implementación más eficaz en el futuro.
Motivaciones de jóvenes argentinos para ser oficiales navales en el siglo XXI: vocación, profesión, ocupación
Authors: Gonzalez Luciano Emanuel 
Published: February 2025

El presente artículo indaga sobre las motivaciones y concepciones que sostienen los jóvenes argentinos para ingresar como oficiales a las Fuerzas Armadas, específicamente, a la Armada Argentina y las incumbencias en la formación del “ser militar”. Esta investigación continúa una serie de pesquisas etnográficas en el ámbito castrense que se desarrollan desde principios del siglo XXI en la Argentina. Para alcanzar el objetivo propuesto, se problematizan tres categorías analíticas formuladas por Moskos (1977): vocación, profesión y ocupación en el marco de los estudios anglosajones sobre Fuerzas Armadas y sociedad. La metodología utilizada es en parte cualitativa; los datos se obtuvieron a partir de entrevistas semiestructuradas tomando una muestra no probabilística intencional por cuotas (n=30) y la observación participante del investigador. También se empleó subsidiariamente una metodología cuantitativa, recurriendo a encuestas elaboradas ad-hoc al total de postulantes a cadetes (n=259).
FINANCIAL LITERACY AMONG HOUSEWIVES TO MANAGE CONSUMPTION PATTERNS AFTER PANDEMIC COVID-19
Authors: Harisanty Dessy , Srirahayu Dyah Puspitasari , Anugrah Esti Putri , Nurpratama Muhammad Rifky 
Published: February 2025

The COVID-19 pandemic has now been running for about 3 years, many community activities are spent at home, bringing new habit patterns for them. One of them is shopping online, since the time of the pandemic people are very accustomed to online shopping patterns. The solution to be able to provide advice on the consumption patterns of consumptive citizens is the introduction of financial literacy, especially through education programs and training on saving habits. This study aims to describe the financial literacy of housewives so that consumer activities can be controlled. The method used in this research is quantitative descriptive, the location of this research is at Plandaan Village, Kedungwaru District, Tulungagung Regency. To determine the sample using a non-random sampling technique that is purposive sampling. The total respondents in this study were 50 housewives. Result of this study shows that housewives have a good general knowledge of personal finance, and have sufficient Savings, Loans, and Investments. Many housewives have funds for emergency needs, so they don't experience confusion when something sudden happens.
Preservation of Medicinal Plants of The Shipibo-Konibo Culture in Primary School Students
Authors: Rango Beldith Rengifo , Vilcanqui Beker Maraza , Choque Gladys Martha Flores , Quispe Jesús Ttito , Ignacio Manuel Calle , Suarez Raúl Tello 
Published: February 2025

Objective: The purpose of the research is to determine the preservation of knowledge about medicinal plants of the Shipibo-Konibo culture in students of the 4th cycle of the Educational Institution No. 64872 B. Nuevo Paraíso of the Masisea district-2021

Theoretical Framework: The topics addressed are explained on the variable medicinal plants with a theoretical basis resulting from scientific research, taken from reliable sources published in impact journals and measurable results.

Method: The study belongs to the quantitative approach, descriptive type and simple descriptive design. The population is made up of 160 students, from which a sample of 50 students was taken between third and fourth grade, to collect the information the survey technique and its instrument the survey form were applied to collect information on the knowledge of medicinal plants of the Shipibo Konibo culture.

Results and Discussion: The results show that children maintain their knowledge of medicinal plants and there is a tendency to lose their use and knowledge of medicinal plants of the Shipibo Konibo culture.

Implications of the research: Despite the existence of conventional medicine, the use of medicinal plants in the jungle is current, and their healing properties must be investigated in depth.

Originality/Value: The importance of the research stands out fundamentally because the ancestral knowledge of medicinal plants is relevant and is an alternative and raw material for research in the field of medicine.
Selection of Materials in The Oxidation Process Caused By Vapors From the Granulation of Metal Slag From the Blast Furnace
Authors: Almeida Júnior Márcio Mendes de , Silveira Dalila Moreira da , Fabiano Demian Patrick , Nucci Edson Romano 
Published: February 2025

Objective: This study aims to evaluate the mechanical behavior and corrosion resistance of coated and uncoated steels, aiming at a longer use of the equipment and metal structures of a blast furnace exposed to specific corrosive environments.

Theoretical Framework: The slag cooling process generates many gases and vapors with various chemical components that contribute to equipment corrosion. Identifying these corrosive agents is important for preventing corrosion and extending the useful life of industrial assets.

Method: The work was developed with a selection of steels by applicability and by resistance to oxidation and temperature, the test specimens in triplicate were placed in two locations, the dry pit, and the silo, over 35 days with mapping of the environment, calculation of mass loss and x-ray diffraction.

Results and Discussion: The results demonstrate the behavior of the specimens and the corrosion rates over time. The agents iron oxides (Fe2O3) and calcium carbonate (CaCO3) had a greater mass loss in ASTM A-36 steel, with a value of 9.1446±3.6503 mm/year in the dry pit. The AISI 310S steel had the lowest mass loss, with a value of 0.0014±0.0004 mm/year in the silo.

Originality/Value: This study contributes to the literature in understanding the corrosive process of slag granulations from a blast furnace. The relevance and value of this research are evidenced by the gain in knowledge of the oxidation mechanisms of the medium, enabling the use of materials and control methods.
National System of Education and Challenges of the Field Education Two Decades After Its Institution as a Modality
Authors: Silva Claudio Rodrigues da , Moraes Agnes Iara Domingos , Torres Julio Cesar 
Published: February 2025

Objective: To establish interrelations between the current context of the school education offered to the countryside people in Brazil - the Education of the Countryside - and aspects of the inconclusive process of consolidation of the National Education System.

Theoretical Reference: Contributions are adopted by authors who analyze the issue of Rural Education from counter-hegemonic perspectives and establish interrelations with political, economic and cultural aspects, in local, regional, national and/or transnational contexts.

Method: It is a bibliographical and documentary study, based on academic productions representative in the debate of the area and federal documents related to the Education of the Field.

Results and Discussion: Starting from an analysis of the historical process of national education, it is concluded that the educational policies implemented in the present day by different federated entities undermine the right to education of the peoples of the countryside and make unfeasible the process of building an effective and democratic National Education System, after more than two decades of the institution of the Education of the Countryside as a modality of school education, a fact that negatively affects or makes unfeasible the effectiveness of the right to contextualized education for the schools of the countryside, as determined by federal legislation.

Research Implications: This study aims to contribute to discussions about Field Education, a pressing and current theme, which demands more research in order to provide data to broaden its understanding, both from the perspective of past and present time.
TEACHER PROFESSIONALISM IN RICHARD LAGRAVENESE’S FREEDOM WRITERS MOVIE
Authors: Astuti Sri Rahayu , Arini Restu 
Published: February 2025

Professionalism is pivotal for teachers because it influences student accomplishment and qualifies educational goals. The demeanor of professional teachers encourages students to develop what is inside them and present it to the world. Based on Socket's professional teacher theory, the study analyzes Lagravenese’s Freedom Writers movie to describe teacher professionalism through Erin Gruwell's character. To answer this problem, literature study, in-depth analysis and descriptive-qualitative methods are used. The study revealed that professional teachers' performance by Erin Gruwell contains five aspects: character, commitment to change and continuous improvement, subject knowledge, pedagogical knowledge, obligations and working relationships outside the classroom. The impact is also seen by the changes in students’ behavior from being difficult to manage to being obedient students with good achievements. Thus, teacher professionalism produces prestige for students making them able to become learners with good behavior, motivation, and academic performance.Keywords: teacher professionalism; teacher competences; student behavior; teacher education.