bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effective measures to bolster the deployment of indoor environmental quality (IEQ) principles in building design: a focus on quantity surveying (QS) firms in Nigeria
Authors: Oke Ayodeji Emmanuel , Aliu John , Agbaje Doyin Helen , Jamir Singh Paramjit Singh , Alade Kehinde Temitope , Samsurijan Mohamad Shaharudin 
Published: December 2023

PurposeResearch on measures to strengthen the implementation of indoor environmental quality (IEQ) principles has been scarce in developing countries such as Nigeria. Hence, this study sought to identify and assess the crucial measures for encouraging the adoption of IEQ principles in the Nigerian construction industry, specifically from the viewpoint of quantity surveyors.Design/methodology/approachTo accomplish this objective, a quantitative research methodology was employed, utilizing a well-structured questionnaire distributed to quantity surveying (QS) firms in Nigeria. The collected data were examined using a range of statistical techniques such as frequencies, percentages, mean item scores (MISs), the Kruskal–Wallis test and exploratory factor analysis.FindingsThe top five ranked measures were as follows: offer financial incentives and tax breaks, develop educational materials and resources, establish clear and accessible reporting mechanisms, develop awards and recognition programs and provide advocacy and awareness campaigns. Factor analysis led to the categorization of the identified measures into four primary clusters: education and training, policy and regulation, incentivization and recognition and collaboration and networking. Consequently, these clusters were renamed the EPIC (Education and training, Policy and regulation, Incentivization and recognition and Collaboration and networking) framework, with each first letter representing a significant measure for fostering the adoption of IEQ principles.Practical implicationsConsequently, this study offers a robust foundation for understanding and implementing measures to enhance the adoption of IEQ principles within the Nigerian construction industry, ultimately benefiting stakeholders and improving the quality of built environments.Originality/valueThe EPIC framework designed in this study offers valuable insights for policymakers, construction industry professionals and other stakeholders interested in promoting IEQ principles, which can potentially lead to healthier, more comfortable and more sustainable built environments in Nigeria and beyond.
Artisan entrepreneurship: influence and network in the development of sustainable strategies in cross-border low-density territories through a Quintuple Helix paradigm
Authors: Rodrigues Alex Olivier , Marques Carla Susana , Ramadani Veland 
Published: December 2023

Purpose
The purpose of this study is, from the perspective of artisan entrepreneurship (AE), to understand how professional and higher education institutions, local authorities, local and cross-border cultural entities and tourism stakeholders perceive AE by collaborating in a network to develop innovative and sustainable strategies, using the Quintuple Helix innovation model.

Design/methodology/approach
Using a qualitative approach, 34 semi-structured interviews were carried out with organisations by emailing them a Google Form. The organisations interviewed were from the north-east of Portugal (Bragança, Miranda do Douro, Mogadouro, Vimioso and Vinhais) and the north of Spain (Zamora Province). The data collected was subjected to content and lexical analysis using the computerised lexical analysis software IRaMuTeQ.

Findings
AE is seen as the representation of a culture where traditional crafts are the identity of a region. The practical and political implications for decision makers in the Quintuple Helix can be seen in the definition of strategies and proposals that should leverage and define regional and cross-border policies, leveraging the need for networking to define concrete measures and programmes for support and training in entrepreneurship and AE, as well as the creation and/or standardisation of existing support networks.

Originality/value
To the best of the authors’ knowledge, this work is the first study to address and deal with the issue of AE by understanding how professional and higher education institutions, local authorities, local and cross-border cultural entities perceive AE and collaborate in a network to develop innovative and sustainable strategies, through the paradigm of the Quintuple Helix model. It also combines a content analysis and a lexical analysis using computerised lexical analysis software – IRaMuTeQ.
Africa rising: turning sporting potential into success
Authors: Agyemang Kwame J.A. , Ayenor Nana Ama , Hammond Marilyn , Bortey Joel Nii Borte 
Published: December 2023

PurposeThe purpose of this essay is to provide a better understanding of Africa's sport industry and demonstrate how the industry can be transformed.Design/methodology/approachTo do so, the authors rely on their varied experiences within Africa's sport ecosystem. This includes reflections based on consuming sport in Africa, studying the sport business landscape, and first-hand experiences working inside African sport organizations.FindingsThe authors find that systemic challenges restrict the growth of Africa's sport industry; however, they maintain there are also reasons to be optimistic about the prospects of the industry.Research limitations/implicationsWhile not an exhaustive list, the authors' commentary defines various research opportunities for scholars interested in both better understanding and improving Africa's sport industry.Practical implicationsThe stated challenges and proposed strategies have the potential to inform decision-makers within Africa's sport ecosystem.Social implicationsCrucial to the continued growth and development of the continent, the authors propose that investments in sport can drive broader economic and social development beyond sport.Originality/valueThe authors address the dearth of academic literature on Africa's sport industry, while also inviting more researchers to undertake research agendas that enhance Africa.
Effects of konjac glucomannan as a freeze‐denaturation inhibitor or binder on the physiochemical properties of heat‐induced gel of freeze‐dried duck blood
Authors: Kim Yea‐Ji , Kim Jake , Kim Tae‐Kyung , Cha Ji Yoon , Shin Dong‐Min , Jung Samooel , Choi Yun‐Sang 
Published: December 2023

AbstractDuring freeze‐drying, the degradation or eutectic melting of duck blood proteins can reduce the quality of duck blood gels. However, the interaction between proteins and polysaccharides during drying can improve protein‐based gel quality. Therefore, here, we investigated the physicochemical properties of heat‐induced gels of freeze‐dried duck blood (FDB) and FDB with different proportions of the polysaccharide konjac glucomannan (KG), which serves as a freeze‐denaturation inhibitor agent (FDA) or binder (BG). The pH and water‐holding capacity (WHC) of FDB + KG gels were higher than those of FDB gel without KG (control). Especially, the WHC increased from 11.00% for control to 55.65% for FDB gel with 1% KG as a BG. Consequently, cooking loss and texture parameters of FDB + KG gels decreased. The hardness of control was 2.14 kg, which significantly reduced to 0.12–0.87 kg with KG addition. The highest carbonyl content was observed in control gel, and the thiobarbituric acid reactive substance content was reduced by the addition of 1% KG as an FDA (T1) or 0.8% KG as an FDA with 0.2% KG as a BG (T2) (p < 0.05). These changes might be induced by the alteration of tertiary structure and thermodynamic stability of gels. In conclusion, 1% KG can be used as an FDA to improve the quality and physicochemical properties of heat‐induced gels of FDB. Optimized FDB gels with KG can be used as an innovative food ingredient to fortify nutrition and develop special dietary purposes.
Physicochemical and thermal properties of pepsin‐ and acid‐soluble collagen isolated from the body wall of sea cucumbers (Stichopus hermanni)
Authors: Shaik Mannur Ismail , Kadir Asmaa Nuha Abdul , Sarbon Norizah Mhd 
Published: December 2023

AbstractThe main objective of this work was to characterize the acid‐soluble collagen (ASC) and pepsin‐soluble collagen (PSC) from the body wall of the sea cucumber scientifically called, Stichopus hermanni. For the extraction of ASC and PSC, the pre‐treated sea cucumber body walls were subjected to 0.5 M acetic acid and 5 g L−1 pepsin, respectively. The yield of ASC (7.30% ± 0.30%) was found to be lower than the PSC (23.66% ± 0.15%), despite both ASC and PSC having similar chemical compositions except for the quantity of protein. The collagens produced from ASC and PSC show maximum peaks on ultraviolet–visible spectroscopic profiles at wavelengths of 230 and 235 nm, respectively, with no significant difference in the maximum temperature (Tmax) of the extracted ASC and PSC. The ASC's coloration was whiter than that of the PSC. As a result, the collagen obtained from the body wall of the sea cucumber showed promise for usage as a substitute for collagen derived from marine sources.Practical ApplicationThe two most popular methods of collagen extraction were acid hydrolysis and enzymatic hydrolysis. To determine whether the extracted collagen is a suitable substitute for animal collagen in different industries, it is required to characterize its physicochemical qualities. This study discovered a new application for marine collagen in the food industry: The sea cucumber has collagen with a greater yield in pepsin extraction with good physicochemical qualities.
Scientific history, biogeography, and biological traits predict presence of cryptic or overlooked species
Authors: Cahill Abigail E. , Meglécz Emese , Chenuil Anne 
Published: December 2023

ABSTRACTGenetic data show that many nominal species are composed of more than one biological species, and thus contain cryptic species in the broad sense (including overlooked species). When ignored, cryptic species generate confusion which, beyond biodiversity or vulnerability underestimation, blurs our understanding of ecological and evolutionary processes and may impact the soundness of decisions in conservation or medicine. However, very few hypotheses have been tested about factors that predispose a taxon to contain cryptic or overlooked species. To fill this gap, we surveyed the literature on free‐living marine metazoans and built two data sets, one of 187,603 nominal species and another of 83 classes or phyla, to test several hypotheses, correcting for sequence data availability, taxon size and phylogenetic relatedness. We found a strong effect of scientific history: the probability of a taxon containing cryptic species was highest for the earliest described species and varied among time periods potentially consistently with an influence of prevailing scientific theories. The probability of cryptic species being present was also increased for species with large distribution ranges. They were more frequent in the north polar and south polar zones, contradicting previous predictions of more cryptic species in the tropics, and supporting the hypothesis that many cryptic species diverged recently. The number of cryptic species varied among classes, with an excess in hydrozoans and polychaetes, and a deficit in actinopterygians, for example, but precise class ranking was relatively sensitive to the statistical model used. For all models, biological traits, rather than phylum, appeared responsible for the variation among classes: there were fewer cryptic species than expected in classes with hard skeletons (perhaps because they provide good characters for taxonomy) and image‐forming vision (in which selection against heterospecific mating may enhance morphological divergence), and more in classes with internal fertilisation. We estimate that among marine free‐living metazoans, several thousand additional cryptic species complexes could be identified as more sequence data become available. The factors identified as important for marine animal cryptic species are likely important for other biomes and taxa and should aid many areas in biology that rely on accurate species identification.
Regulation of the innate immune response and gut microbiome by p53
Authors: Khor Amy Hui Ping , Koguchi Tomoyuki , Liu Hao , Kakuta Masanori , Matsubara Daisuke , Wen Ruimeng , Sagiya Yoji , Imoto Seiya , Nakagawa Hidewaki , Matsuda Koichi , Tanikawa Chizu 
Published: December 2023

Abstractp53 is a key tumor suppressor mutated in half of human cancers. In recent years, p53 was shown to regulate a wide variety of functions. From the transcriptome analysis of 24 tissues of irradiated mice, we identified 553 genes markedly induced by p53. Gene Ontology (GO) enrichment analysis found that the most associated biological process was innate immunity. 16S rRNA‐seq analysis revealed that Akkermansia, which has anti‐inflammatory properties and is involved in the regulation of intestinal barrier integrity, was decreased in p53‐knockout (p53−/−) mice after radiation. p53−/− mice were susceptible to radiation‐induced GI toxicity and had a significantly shorter survival time than p53‐wild‐type (p53+/+) mice following radiation. However, administration of antibiotics resulted in a significant improvement in survival and protection against GI toxicity. Mbl2 and Lcn2, which have antimicrobial activity, were identified to be directly transactivated by p53 and secreted by liver into the circulatory system. We also found the expression of MBL2 and LCN2 was decreased in liver cancer tissues with p53 mutations compared with those without p53 mutations. These results indicate that p53 is involved in shaping the gut microbiome through its downstream targets related to the innate immune system, thus protecting the intestinal barrier.
Unilateral intraindividual comparison and bilateral performance of a monofocal spherical and diffractive extended depth of field intraocular lens mix‐and‐match approach
Authors: Wendelstein Jascha A. , Casazza Marina , Reifeltshammer Sophia , Riaz Kamran , Pantanelli Seth , Mariacher Siegfried , Seiler Theo G. , Kohnen Thomas , Bolz Matthias 
Published: December 2023

AbstractBackgroundTo evaluate the intraindividual visual performance of a spherical and extended depth of field (EDOF) IOL used in a mix‐and‐match approach.MethodsSingle centre (tertiary care centre), retrospective consecutive case series. Included patients had uneventful cataract surgery with implantation of a spherical monofocal IOL (CT Spheris 204) in the dominant eye and a diffractive EDOF IOL (AT LARA 829) in the non‐dominant eye. Monocular and binocular defocus curves and visual acuity at various distances were assessed. In addition, binocular reading speed, contrast sensitivity, and patient satisfaction using QOV, Catquest 9SF, and glare/halo questionnaires are reported.ResultsA total of 29 patients (58 eyes) were included. We observed significant intra‐individual differences for monocular DCIVA, DCNVA, UIVA, and UNVA. There were no differences in monocular BCDVA or UDVA. The monocular defocus curves for the two IOLs significantly differed at defocus steps between −1.0 and −3.5 D. 93.10% of patients reported they would opt for the same combination of IOLs.ConclusionExcellent uncorrected and corrected distance visual acuity was demonstrated in both groups. The mix‐and‐match approach described in this study yielded good intermediate vision and improved near vision with high‐patient satisfaction.
Severe communication delays are independent of seizure burden and persist despite contemporary treatments in SCN1A+ Dravet syndrome: Insights from the ENVISION natural history study
Authors: Perry M. Scott , Scheffer Ingrid E. , Sullivan Joseph , Brunklaus Andreas , Boronat Susana , Wheless James W. , Laux Linda , Patel Anup D. , Roberts Colin M. , Dlugos Dennis , Holder Deborah , Knupp Kelly G. , Lallas Matt , Phillips Steven , Segal Eric , Smeyers Patricia , Lal Dennis , Wirrell Elaine , Zuberi Sameer , Brünger Tobias , Wojnaroski Mary , Maru Benit , O'Donnell Penrose , Morton Magda , James Emma , Vila Maria Candida , Huang Norman , Gofshteyn Jacqueline S. , Rico Salvador 
Published: December 2023

AbstractObjectiveDravet syndrome (DS) is a developmental and epileptic encephalopathy characterized by high seizure burden, treatment‐resistant epilepsy, and developmental stagnation. Family members rate communication deficits among the most impactful disease manifestations. We evaluated seizure burden and language/communication development in children with DS.MethodsENVISION was a prospective, observational study evaluating children with DS associated with SCN1A pathogenic variants (SCN1A+ DS) enrolled at age ≤5 years. Seizure burden and antiseizure medications were assessed every 3 months and communication and language every 6 months with the Bayley Scales of Infant and Toddler Development 3rd edition and the parent‐reported Vineland Adaptive Behavior Scales 3rd edition. We report data from the first year of observation, including analyses stratified by age at Baseline: 0:6–2:0 years:months (Y:M; youngest), 2:1–3:6 Y:M (middle), and 3:7–5:0 Y:M (oldest).ResultsBetween December 2020 and March 2023, 58 children with DS enrolled at 16 sites internationally. Median follow‐up was 17.5 months (range = .0–24.0), with 54 of 58 (93.1%) followed for at least 6 months and 51 of 58 (87.9%) for 12 months. Monthly countable seizure frequency (MCSF) increased with age (median [minimum–maximum] = 1.0 in the youngest [1.0–70.0] and middle [1.0–242.0] age groups and 4.5 [.0–2647.0] in the oldest age group), and remained high, despite use of currently approved antiseizure medications. Language/communication delays were observed early, and developmental stagnation occurred after age 2 years with both instruments. In predictive modeling, chronologic age was the only significant covariate of seizure frequency (effect size = .52, p = .024). MCSF, number of antiseizure medications, age at first seizure, and convulsive status epilepticus were not predictors of language/communication raw scores.SignificanceIn infants and young children with SCN1A+ DS, language/communication delay and stagnation were independent of seizure burden. Our findings emphasize that the optimal therapeutic window to prevent language/communication delay is before 3 years of age.
Estimating recreational trap‐fishing effort for crayfish from zig‐zag line transects, drone surveys and enforcement surveys
Authors: Sundblad Göran , de Groote Annica , Lundquist Peter , Larsson Mattias , Linderfalk Rasmus , Larson Fredrik 
Published: December 2023

AbstractEstimates of recreational fishing effort and catch are needed to inform fisheries management, but such estimates can be challenging to obtain. We combined a zig‐zag line transect survey of buoys, a fisheries enforcement survey and a drone survey to estimate recreational effort in the open‐access trap fishery for signal crayfish (Pacifastacus leniusculus) in the sixth largest lake in Europe, Lake Vättern, Sweden. Using supporting variables such as size of nearby ports and bathymetry, our model‐assisted estimate of total effort was 6400 (±4300 CI) buoys during the three‐weekend season. Using the frequency of buoys to traps as a constant, the total number of crayfish traps was estimated to be 25,500 (±17,000 CI). The sampling design and methods presented are useful for ecologists and resource managers to design future multi‐source surveys of recreational trap fishing effort.
RETRACTED: Effect of wound infiltration of dexmedetomidine in lumbar spine surgery on postoperative wound pain: A meta‐analysis
Authors: Wang Xiaoping , Peng Yao , Si Yao , Hu Xi 
Published: December 2023

AbstractIn a meta‐study, we evaluated the effectiveness and security of the combination of topical anaesthetic and dexmedetomidine in the treatment of postoperative pain in patients with lumbar disease. Four databases were systematically searched for possible related articles. Only English‐language research was taken into account on the Internet. Furthermore, we only took into account the studies that were published prior to 2023. Only those that fulfilled the eligibility criteria were considered: (1) in adults who were about to undergo spine operation, (2) dexmedetomidine combined with local anaesthesia, (3) Visual Analog Scale scores at 4 and 24 h after the event and (4) this was a randomized or nonrandomized, controlled study. The meta‐analysis was carried out with Revman 5.3 software. A ROBINS‐I‐based instrument was used to evaluate controlled studies. All trials were synthesized by computing the end results with either a fixed or a random effect model, which was dependent on statistical diversity. Five trials showed a marked reduction in wound pain at 4 h after the operation in patients who were treated with dexmedetomidine for lumbar spinal surgery (MD, −0.81; 95% CI, −1.24, −0.35; p = 0.0005). In the case of lumbar spinal operations, the addition of dexmedetomidine to the postoperative treatment resulted in a marked reduction in the pain at 24 h post‐operation (MD, −0.64; 95% CI, −0.79, −0.48; p < 0.0001). The quality of the data we evaluated was ‘moderate’ to ‘good’; thus, we have limited confidence in the impact estimation, and the actual impact might be significantly different from what we had expected. Additional studies should concentrate on practices that are well known to cause severe postoperative pain, especially for cases where the improvement of pain management may lead to substantial clinical benefits in terms of reduction of morbidity or cost‐effectiveness in terms of quicker healing and release.
The richer, the better? Effects of combining seductive and interpretational visuals in computer‐based learning
Authors: Wang Zhe , Abercrombie Sara , Wong Rachel , Ren Yuxin , Dai Shiting 
Published: December 2023

AbstractBackgroundThere are two major types of pictures that have been the focus of multimedia learning research, namely, seductive and interpretational pictures. Despite an increasing body of literature documenting the effects of either seductive or interpretational pictures added to text‐based materials, there is a paucity of research explicitly comparing them in a multimedia learning environment.ObjectivesTo address this gap, this study manipulated the picture condition by designing seductive pictures (SPs), interpretational pictures (IPs), and seductive plus interpretational pictures (SIPs) and investigated the multimedia effects of SPs, IPs, and SIPs on several cognitive and affective‐motivational variables.MethodsTwo computer‐based experiments were conducted where a scientific text about the blood circulatory system was presented with SPs, IPs, or SIPs. Participants were randomly assigned to one of the three conditions, and completed a subsequent learning test (comprehension and transfer questions) as well as a survey measuring their learning experience.Results and ConclusionsThe results of the two experiments were consistent in showing that our experimental manipulation was unsuccessful in influencing the learning outcome variables. Nevertheless, learning with seductive plus interpretational pictures appeared to yield better judgement accuracy, as compared to learning with seductive or interpretational pictures only. Most educational practitioners still include decorative elements based on their impression of aesthetics of motivation; this study encourages them to use these elements within their learning materials.