bluuebunny/crossref_metadata_2025_split huggingface dataset:
Regulation of ester contents enabled tunable thermal and mechanical properties of poly(ester amide)
Authors: Liu Yihuan , Zuo Guoqing , Gao Han , Wu Zhao , Huang Wei , Ma Canliang , Yin Jie , Hu Xin , Zhu Ning , Guo Kai 
Published: October 2023

AbstractPoly(ε‐caprolactone‐co‐ε‐caprolactam) was synthesized through ring‐opening copolymerization of ε‐caprolactone (CLO) and ε‐caprolactam catalyzed by ethylmagnesium bromide (EtMgBr) or sodium ε‐caprolactam. Varied ester contents were achieved from 0 to 100 mol%. EtMgBr enabled the copolymerization with high yield of over 95%. Thermal properties vary with different ester contents. With increasing CLO content, the onset decomposition temperature (273.36 to 240.97 °C) and glass transition temperature (52.1 to −56.3 °C) gradually decreased. The results of melting behavior of resultant poly(ester amide)s through differential scanning calorimetry and theoretical calculation indicated a eutectic temperature of 46.6 °C. The mechanical properties of obtained copolymers were systematically investigated. The enhancement of CLO incorporation led to a decrease in tensile strength (70.99 to 9.88 MPa) and Young's modulus (690.03 to 19.18 MPa). Copolymer with CLO incorporation of 70 mol% exhibited a eutectic temperature of 46.6 °C, and enabled a high elongation at break (658%) and enhanced impact strength (138.5 kJ m−2). © 2023 Society of Chemical Industry.
Biological role of fructose in the male reproductive system: Potential implications for prostate cancer
Authors: Echeverría Carolina E. , Oyarzún Vanessa I. , López‐Cortés Andrés , Cancino Jorge , Sotomayor Paula C. , Goncalves Marcus D. , Godoy Alejandro S. 
Published: October 2023

AbstractBackgroundOver the last 20 years, fructose has gradually emerged as a potential metabolic substrate capable of promoting the growth and progression of various cancers, including prostate cancer (PCa). The biological and molecular mechanisms that underlie the effects of fructose on cancer are beginning to be elucidated.MethodsThis review summarizes the biological function of fructose as a potential carbon source for PCa cells and its role in the functionality of the male reproductive tract under normal conditions.ResultsThe most recent biological advances related to fructose transport and metabolism as well as their implications in PCa growth and progression suggest that fructose represent a potential carbon source for PCa cells. Consequently, fructose derivatives may represent efficient radiotracers for obtaining PCa images via positron emission tomography and fructose transporters/fructose‐metabolizing enzymes could be utilized as potential diagnostic and/or predictive biomarkers for PCa.Conclusion:The existing data suggest that restriction of fructose from the diet could be a useful therapeutic strategy for patients with PCa.
Study of protonated dimers of cytosine, cytidine, and deoxycytidine using survival yield method and quantum mechanics calculations
Authors: Jankowski Wojciech , Hoffmann Marcin , Półrul Paulina , Frańska Magdalena 
Published: October 2023

RationaleCytosine and its conjugates are prone to form protonated, triply‐bonded dimers. Therefore, the nucleic‐acid cytosine‐rich sequence forms the four‐stranded noncanonical secondary structure known as the intercalated motif (i‐motif). This process has resulted in studies on cytosine protonated dimers. This communication focuses on the protonated dimers of cytosine and its nucleoside using the survival yield (SY) method and quantum mechanics calculations.MethodsTo obtain the precursor ion fragmentation curve, the plot of SY against Ecomδ, the product ion spectra of the protonated dimers were obtained using a Waters/Micromass Q‐TOF Premier mass spectrometer. Quantum mechanics calculations were performed using GAUSSIAN 16, and full geometry optimizations and energy calculations were performed within the density functional theory framework at B3LYP/6‐31G(d,p).ResultsThe precursor ion fragmentation curve allowed the rating of the gas‐phase stabilities of the analyzed protonated dimers. Substitution of sugar moiety at N1 cytosine atom decreased the gas‐phase stabilities of the protonated dimers. The deoxycytidine dimer was found to be more stable than the cytidine dimer and cytidine–deoxycytidine dimer. Quantum chemical calculations indicated that cytosine aminohydroxy tautomer may be involved in the formation of protonated cytosine–cytosine nucleoside dimers but not in the formation of cytosine dimers.ConclusionsThe results obtained for nucleoside dimers indicated that the SY method may reflect the i‐motif stabilities observed under physiological conditions. Therefore, the analysis of other protonated dimers of variously substituted cytosine–cytosine nucleoside using the SY method may be important to study the effect of cytosine substitution on the i‐motif stabilities. Cytosine tautomer containing C2‐OH… N(2H)‐C4 moiety may be involved in the formation of protonated cytosine–cytosine nucleoside dimers.
Sleep in NCAA Division I collegiate athletes: Relations with self‐compassion, stress, and rumination
Authors: Assar Arash , Lueke Niloufar A. , Eouanzoui Kianré B. , Bolin Jocelyn H. 
Published: October 2023

AbstractThe purpose of the present study was to investigate whether the benefits of self‐compassion on sleep difficulties extend to a sample of National Collegiate Athletic Association (NCAA) Division I college athletes, and to examine the unique contributions of two possible pathways that have been separately evidenced to underlie the self‐compassion and sleep difficulties association in non‐athlete populations – namely perceived stress and rumination. A total of 412 NCAA Division I college athletes (M = 19.88, SD = 1.50) from 16 different West, Midwest, South, and North‐eastern universities completed the Self‐Compassion Scale, Perceived Stress Scale‐10, Rumination‐Reflection Questionnaire, and the Pittsburgh Sleep Quality Index. Findings indicated that self‐compassion is associated with fewer sleep difficulties in college athletes, and that lower levels of perceived stress and rumination are independent mechanisms through which self‐compassion is associated with sleep difficulties. Further, a comparison of the indirect effects revealed that perceived stress had a significantly stronger indirect effect on the relation between self‐compassion and sleep difficulties than rumination. This study provides initial support for self‐compassion training as a potentially relevant and important resource for promoting mental health and sleep health in the context of collegiate sport.
Engineered Macrophage Membrane‐Coated Nanoparticles with Enhanced CCR2 Expression Promote Spinal Cord Injury Repair by Suppressing Neuroinflammation and Neuronal death
Authors: Gu Changjiang , Geng Xiangwu , Wu Yicheng , Dai Yuya , Zeng Junkai , wang Zhenqiang , Fang Huapan , Sun Yanqing , Chen Xiongsheng 
Published: October 2023

AbstractSpinal cord injury (SCI) is a severe neurological disorder characterized by significant disability and limited treatment options. Mitigating the secondary inflammatory response following the initial injury is the primary focus of current research in the treatment of SCI. CCL2 (C─C motif chemokine ligand 2) serves as the primary regulator responsible for inflammatory chemotaxis of the majority of peripheral immune cells, blocking the CCL2‐CCR2 (C─C chemokine receptor type 2) axis has shown considerable therapeutic potential for inflammatory diseases, including SCI. In this study, it presents a multifunctional biomimetic nanoplatform (CCR2‐MM@PLGA/Cur) specifically designed to target the CCL2‐CCR2 axis, which consisted of an engineered macrophage membrane (MM) coating with enhanced CCR2 expression and a PLGA (poly (lactic‐co‐glycolic acid)) nanoparticle that encapsulated therapeutic drugs. CCR2 overexpression on MM not only enhanced drug‐targeted delivery to the injury site, but also attenuated macrophage infiltration, microglia pro‐inflammatory polarization, and neuronal apoptosis by trapping CCL2. Consequently, it facilitated neural regeneration and motor function recovery in SCI mice, enabling a comprehensive treatment approach for SCI. The feasibility and efficacy of this platform are confirmed through a series of in vitro and in vivo assays, offering new insights and potential avenues for further exploration in the treatment of SCI.
Combined Funnel, Concentrator, and Particle Valve Functional Element for Magnetophoretic Bead Transport Based on Engineered Magnetic Domain Patterns
Authors: Huhnstock Rico , Paetzold Lukas , Merkel Maximilian , Kuświk Piotr , Ehresmann Arno 
Published: October 2023

AbstractControlled actuation of superparamagnetic beads (SPBs) within a microfluidic environment using tailored dynamic magnetic field landscapes (MFLs) is a potent approach for the realization of point‐of‐care diagnostics within Lab‐on‐a‐chip (LOC) systems. Making use of an engineered magnetic domain pattern as the MFL source, a functional LOC‐element with combined magnetophoretic “funnel”, concentrator, and “valve” functions for micron‐sized SPBs is presented. A parallel‐stripe domain pattern design with periodically decreasing/increasing stripe lengths is fabricated in a topographically flat continuous exchange biased (EB) thin film system by ion bombardment induced magnetic patterning (IBMP). It is demonstrated that, upon application of external magnetic field pulses, a fully reversible concentration of SPBs at the domain pattern's focal point occurs. In addition, it is shown that this functionality may be used as an SPB “funnel”, allowing only a maximum number of particles to pass through the focal point. Adjusting the pulse time length, the focal point can be clogged up for incoming SPBs, resembling an on/off switchable particle “valve”. The observations are supported by quantitative theoretical force considerations.
Toward High‐Performance Mg/S Batteries with M4‐Assisted Mg(AlCl4)2/PYR14TFSI/DME Electrolyte and MoS2@CMK/S Cathode
Authors: Li Yabing , Cheng Miao , Liu Qianqian , Wang Ruirui , Ma Wujun , Li Xin , Hu Jing , Wei Tao , Liu Chengbao , Ling Yun , Liu Bo , Chen Muzi , Li Wanfei 
Published: October 2023

AbstractRechargeable magnesium batteries (RMBs) are considered as one of the most promising candidates for next‐generation batteries. However, the popularization of RMBs is seriously plagued due to the lack of suitable non‐nucleophilic electrolytes and the passivation of Mg anode. Herein, a novel non‐nucleophilic electrolyte is developed by introducing (s)‐1‐methoxy‐2‐propylamine (M4) into themagnesium aluminum chloride complex (MACC)‐like electrolyte. The as‐synthesizes Mg(AlCl4)2‐IL‐DME‐M4 electrolyte enables robust reversible cycling of Mg plating/stripping with low overpotential, high anodic stability, and ionic conductivity (8.56 mS cm−1). These features should be mainly attributed to the in situ formation of an MgF2 containing Mg2+‐conducting interphase, which dramatically suppresses the passivation and parasitic reaction of Mg anode with electrolyte. Remarkably, the Mg/S batteries assemble with as‐synthesize electrolyte and a new type MoS2@CMK/S cathode deliver unprecedented electrochemical performance. Specifically, the Mg/S battery exhibited the highest reversible capacity up to 1210 mAh g−1 at 0.1 C, excellent rate capability and satisfactory long‐term cycling stability with a reversible capacity of 370 mAh g−1 (coulombic efficiency of ≈100%) at 1.0 C for 600 cycles. The study findings provide a novel strategy and inspiration for designing efficient non‐nucleophilic Mg electrolyte and suitable sulfur‐host materials for practical Mg/S battery applications.
Two Birds with One Stone: Contemporaneously Enhancing OER Catalytic Activity and Stability for Dual‐Phase Medium‐Entropy Metal Sulfides
Authors: Li Fengqi , Wu Hao , Lv Shaochen , Ma Yujie , Wang Biao , Ren Yilun , Wang Cong , Shi Yuxuan , Ji Hurong , Gu Jian , Tang Shaochun , Meng Xiangkang 
Published: October 2023

AbstractTransition metal‐based sulfides exhibit remarkable potential as electrocatalysts for oxygen evolution reaction (OER) due to the unique intrinsic structure and physicochemical characteristics. Nevertheless, currently available sulfide catalysts based on transition metals face a bottleneck in large‐scale commercial applications owing to their unsatisfactory stability. Here, the first fabrication of (FeCoNiMn2)S2 dual‐phase medium‐entropy metal sulfide (dp‐MEMS) is successfully achieved, which demonstrated the expected optimization of stability in the OER process. Benefiting from the “cell wall” ‐like structure and the synergistic effect in medium‐entropy systems, (FeCoNiMn2)S2 dp‐MEMS delivers an exceptionally low overpotential of 169 and 232 mV at current densities of 10 and 100 mA cm−2, respectively. The enhancement mechanism of catalytic activity and stability is further validated by density functional theory (DFT) calculations. Additionally, the rechargeable Zn–air batteries integrated with FeCoNiMn2)S2 dp‐MEMS exhibit remarkable performance outperforming the commercial catalyst (Pt/C+RuO2). This work demonstrates that the dual‐phase medium‐entropy metal sulfide‐based catalysts have the potential to provide a greater application value for OER and related energy conversion systems.
Hydrogel and Nanomedicine‐Based Multimodal Therapeutic Strategies for Spinal Cord Injury
Authors: Yin Peng , Liang Weishi , Han Bo , Yang Yihan , Sun Duan , Qu Xianjun , Hai Yong , Luo Dan 
Published: October 2023

AbstractSpinal cord injury (SCI) is a severe neurodegenerative disease caused by mechanical and biological factors, manifesting as a loss of motor and sensory functions. Inhibition of injury expansion and even reversal of injury in the acute damage stage of SCI are important strategies for treating this disease. Hydrogels and nanoparticle (NP)‐based drugs are the most effective, widely studied, and clinically valuable therapeutic strategies in the field of repair and regeneration. Hydrogels are 3D flow structures that fill the pathological gaps in SCI and provide a microenvironment similar to that of the spinal cord extracellular matrix for nerve cell regeneration. NP‐based drugs can easily penetrate the blood‐spinal cord barrier, target SCI lesions, and are noninvasive. Hydrogels and NPs as drug carriers can be loaded with various drugs and biological therapeutic factors for slow release in SCI lesions. They help drugs function more efficiently by exerting anti‐inflammatory, antioxidant, and nerve regeneration effects to promote the recovery of neurological function. In this review, the use of hydrogels and NPs as drug carriers and the role of both in the repair of SCI are discussed to provide a multimodal strategic reference for nerve repair and regeneration after SCI.
Bauingenieur der ersten Nachkriegsgeneration
Authors: Werner Frank , Hunger Hans‐Reinhard 
Published: October 2023

AbstractIm Dezember des Jahres 2023 blicken wir zurück auf den 100. Geburtstag von Prof. Dr.‐Ing. habil. Peter Hofmann, einen Wissenschaftler, Hochschullehrer und Praktiker der alten Schule. In einer Zeit der Diskussionen über außerordentliche Belastungen und komplizierter werdende Lebensverhältnisse ist es interessant, einen Blick zurückzuwerfen auf eine Lebenswelt, die sich in ihren Anforderungen und Umständen deutlich von den heutigen Erfahrungen, Ansichten und Lebensplanungen unterschieden hat. Nach dem Studium und Diplom an der TU Dresden arbeitete er als Assistent am dortigen Lehrstuhl für Stahlbau, promovierte und habilitierte. Im Jahre 1967 erfolgte die Berufung als ordentlicher Professor an die Hochschule für Architektur und Bauwesen Weimar. Hier arbeitete er bis zu seiner Emeritierung im August 1989. Seine Forschungsarbeiten umfassten ein weites Spektrum. Im Zuge der Einführung der neuen Generation von Stahlbaunormen begründete Prof. P. Hofmann im Jahre 1971 die Informationstagung Metallbau, die bis in die 1990er‐Jahre durchgeführt wurde. Prof. P. Hofmann konnte auf eine umfangreiche Publikationstätigkeit zurückblicken. Hervorzuheben ist die zielgerichtete Betreuung seiner Mitarbeiter. An der Weimarer Hochschule wurden von ihm 28 Promotionen intensiv betreut und erfolgreich abgeschlossen. Prof. Dr.‐Ing. habil. Peter Hofmann verstarb im Mai 2015.
1,3‐Acetonedicarboxylic Acid as a Simple Stimulus for Reversible Time‐Controlled pH Modulation
Authors: Verdoot Vincent , Quintard Adrien 
Published: October 2023

AbstractImplementation of new activated carboxylic acids is crucial to switch reversibly chemical systems over time in a safer manner. By applying cheap 1,3‐acetonedicarboxylic acid, the pH of aqueous solutions can be decreased before autonomously evolving over time back again to a higher value upon diacid decarboxylation. This decarboxylation can be catalysed by different species such as simple amines or simple metals such as iron and copper salts. This process generates 2 molecules of CO2 and acetone as single waste, considerably decreasing the toxicity associated with such activated acids. The potential of this weak diacid was confirmed by reversibly disrupting a strong gel upon diacid addition and opens the way to the application in complex chemically fuelled systems.
Report of the Special‐purpose Committee on DNA Sequences as Types, established at the XIX International Botanical Congress in Shenzhen, China
Authors: Lehtonen Samuli , Thiele Kevin R. 
Published: October 2023

AbstractA Special‐purpose Committee on DNA Sequences as Types was established at the XIX International Botanical Congress (IBC) in Shenzhen, China in 2017, with a mandate to report to the XX IBC with recommendations on a preferred course of action with respect to DNA sequences as potential types under the International Code of Nomenclature for algae, fungi, and plants. This report provides a synthesis of the deliberations from the Special‐purpose Committee on this issue. We discuss two potential options for dealing with the problem that many species, especially of microfungi and microalgae, can be discovered and delimited using eDNA sequencing but cannot currently be formally named due to the requirement in the Code that either a specimen or illustration be nominated as holotype. One option is to expand the definition of “type” to include DNA sequences, while a second option would allow some taxa to be named without types, the application of their names instead being determined using a DNA sequence. This report should be read in concert with two formal proposals for potential amendments to effect these options, published in this issue of Taxon.
Co-production of Knowledge on Climate Change Adaptation in Reindeer Sámi Culture: Research Methodology and Ethics
Authors: Näkkäläjärvi Klemetti , Juntunen Suvi 
Published: October 2023

AbstractThis paper presents part of the results of the “Feasibility study on co-production of knowledge between researchers and Indigenous communities for climate change adaptation” project. The research hypothesis was that academia and Sámi communities could find ways for culturally sustainable adaptation with the ethical and systematic co-production of knowledge. The research material comprises six workshops organized in the Finnish Sámi homeland with Sámi reindeer herders. Traditional knowledge and expertise of the Sámi people were considered equal alongside academic knowledge. The workshops conveyed distrust of researchers but considered future collaboration with the academia important. Participants identified critical prerequisites for research collaboration with the academia: the projects need to support the reindeer herding culture, and Sámi participation has to be included in the projects from the beginning. The chapter provides a procedure for the ethical co-production of knowledge in the reindeer Sámi context. Effects of climate change are widespread in Sámi reindeer herding culture. Workshops concluded that climate adaptation requires, among other things, action from the administration; collaboration with reindeer herders, authorities, and researchers; and the development of the status of reindeer herding.
Reindeer Husbandry Trends: Nenets Autonomous Okrug and Western Finnmark
Authors: Degteva Anna , Okotetto Elvira , Slepushkin Igor , Romanenko Tatyana , Borodina Alexandra , Mathiesen Svein Disch 
Published: October 2023

AbstractNenets Autonomous Okrug (Nenets AO) in Russia and Western Finnmark in Norway are two large reindeer husbandry regions in the circumpolar North. The Soviet Union pioneered the industrialization and collectivization of reindeer husbandry in Nenets AO in the 1930s, while structural and rational practices of Sámi pastoralism in Western Finnmark started in the 1970s. Both regions aimed to increase meat production by manipulating the herd size and structure, seasonal calf slaughtering, changing reindeer ownership, and introducing novel labor standards such as shift working, housing programs, and mobile cabins for the herders. Experimental science of rational reindeer husbandry in the Soviet Union might have inspired reforms and a new model for reindeer husbandry established in Norway in 1976. This paper analyzes trends in reindeer husbandry in Nenets AO and Western Finnmark in light of these structural changes. An increase followed the expanded proportions of females during these periods of change in the total number of reindeer in both regions. However, we observed significant differences between trends in reindeer husbandry in Nenets AO and Western Finnmark. We conclude that while Norway implemented an adjusted version of the Soviet model with as much as 90–95% females in the herd and started slaughtering calves instead of adult females and 1.5 years old males, Soviet structural and rational practices never encompassed more than 65% females. Before this reform, 45% of the herd in Norway were traditionally females. Trend analyses in Western Finnmark and Nenets AO indicate that Norway’s extreme implementation of the new reindeer husbandry model increased the variability of calf production in Western Finnmark compared to calf production in Nenets AO. Despite Norwegian subsidies and policies encouraging high female percentages, a regression analysis based on data from 1981–2018 showed a negative correlation between the percentage of productive females and calf productivity in Western Finnmark. The rationale for the change in the management model in Norway in the 1970s was based on the assumption that reindeer herders in the North did not fully utilize the potential of the favorable climate conditions in Finnmark. However, in the past years, winters in Western Finnmark have changed. Increased winter air temperatures and changing snow conditions affect female reindeer. We conclude that Norway’s modernization program for Sámi reindeer husbandry in Western Finnmark resulted in a highly volatile production of reindeer calves that negatively affected reindeer herders’ food security and herding economy. The top-down productivity policy model for reindeer husbandry in Norway was weakly nested within Sámi herders’ traditional cultures and knowledge.