bluuebunny/crossref_metadata_2025_split huggingface dataset:
FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN KEJADIAN ANEMIA PADA IBU HAMIL TRIMESTER III
Authors: Suyani  
Published: November 2023

This study aims to determine the factors associated with the incidence of anemia in third trimester pregnant women at BPM Tri Rahayu Setyaningsih. This study used a quantitative design with a cross sectional study design. The sample in this study was taken with a total sampling technique of 59 respondents. The data used secondary data, by analyzing the cohort of pregnant women and classifying the factors associated with the incidence of anemia. Data analysis used Chi Square statistical test. The results showed that the incidence of anemia in pregnant women in the third trimester at BPM Tri Rahayu Setyaningsih was 26 people (44.1%). Based on the Chi Square statistical test with a significance level of 0.05, it was found that there was a relationship between pregnancy distance and the incidence of anemia with a p-value. value 0.001, there is a relationship between age and the incidence of anemia with a p-value of 0.018, there is a relationship between the frequency of ANC and the incidence of anemia with a p-value of 0.035, there is a relationship between parity and the incidence of anemia with a p-value of 0.001 and there is a relationship between status nutrition and the incidence of anemia with a p-value of 0.001.
The results of logistic regression analysis showed that the factor that most influenced the incidence of anemia in pregnant women was the pregnancy distance OR value of 10.4 (95% CI: 2.35-7.21) which means that the risk pregnancy distance is <2 years and > 10 years are more likely to experience anemia 10.4 times compared to pregnant women whose pregnancy is not at risk (2-10 years).
Gambaran Pelaksanaan Deteksi Dini Inspeksi Visu L Asam Asetat (IVA) Terhadap Kejadian Kanker Serviks Pada Wanita Usia Subur Di Puskesmas Purwojati
Authors: Dewi Sawitri 
Published: November 2023

Cancer is a health problem for people around the world, according to data from the World Health Organization (WHO), cervical cancer contributes 12% of all cancers affecting women and is the second leading cause of death for women in Indonesia after breast cancer. Every day, it is estimated that 41 new cases occur and 20 women die from the disease. Because of the high risk factors for this disease, women should do early detection, one of which is the Acetic Acid Visual Inspection (IVA) method. This method is relatively simple, comfortable and practical. IVA is a method for early detection of cervical cancer using 3-5% acetic acid, and has an accuracy of 90%. The purpose of this study was to determine the implementation of early detection of IVA on the incidence of cervical cancer in women of childbearing age in the Purwojati Health Center, Banyumas Regency. The research design used an analytic survey with a cross sectional approach. The sampling technique used accidental sampling. Data processing was carried out by using the Chi-Square (X2) test.
The results showed that the incidence of cervical cancer was 15%, most women of childbearing age did not perform early detection of cervical cancer with the IVA method because of ignorance and shame.
ABOUT THE FEATURES OF INTONATION DEVELOPMENT IN THOMAS ADES’S OPERA “THE TEMPEST”
Authors: Володягина Д.А. 
Published: November 2023

В фокусе статьи находится опера «Буря» современного британского композитора Томаса Адеса, в 2004 году пополнившая список выдающихся музыкальных воплощений известного шекспировского сюжета. Одновременно с очевидными свежестью и сложностью музыкального языка сочинения, оперный театр «The Tempest» оказывается во многом традиционен в драматическом и композиционном планах. Сольные, ансамблевые и хоровые эпизоды составляют органичное целое, скреплённое приметой поствагнеровской оперы: интонационным сюжетом произведения (термин Н. И. Дегтяревой). В статье показано, что в опере Адеса «Буря» этот сюжет выстраивается с помощью развития и взаимодействия лейткомплексов (основных персонажей и ключевых явлений) и лейтэмблем (основных персонажей и важных топонимов), выявляя симфоничность мышления композитора.
The article focuses on the opera «The Tempest» by the contemporary British composer Thomas Adès. In 2004 «The Tempest» joined the list of outstanding musical embodiments of the famous Shakespearean plot. Simultaneously with the obvious freshness and complexity of the music language of the composition, the opera theater «The Tempest» turns out to be largely traditional in dramatic and compositional terms. Solo, ensemble and choral episodes form an organic influenced by the post-Wagner opera the intonation plot of the work (the term of N. I. Degtyareva [1]). This study shows that in the opera «The Tempest» by Ades the plot is built through the development and interaction of leitcomplexes (main characters and key phenomena) and leitembles (main characters and important toponyms), revealing the symphonic thinking of the composer.
Borderline hypernatraemia and mortality rates in South African infants: A single-centre observational study
Authors: Naka N , Solomon F , Madhi S A , Izu A , Pettifor J M , Dangor Z , Lala S G 
Published: November 2023

Background. In children, hypernatraemia occurs most commonly in infants (younger than 1 year). Although hypernatraemia is associated with high mortality and morbidity rates, it is variably defined in the paediatric literature as either serum sodium ≥150 mmol/L or serum sodium >145 mmol/L. In hospitalised adults, a serum sodium level >145 mmol/L but <150 mmol/L (called borderline hypernatraemia) has recently been identified as an independent risk factor for mortality. There are limited data about a potential association between borderline hypernatraemia and mortality in infants.
Objectives. To determine whether borderline hypernatraemia is associated with increased mortality in hospitalised infants.
Methods. We conducted a single-centre, retrospective observational study of 8 343 infants admitted to a tertiary-level academic hospital in Johannesburg, South Africa, of whom 254 had borderline hypernatraemia, 376 had hypernatraemia (serum sodium ≥150 mmol/L), and 7 713 did not have hypernatraemia. Mortality rates were reported as odds ratios (ORs) with 95% confidence intervals (CIs).
Results. In 254 infants with borderline hypernatraemia, 115 (45.3%) were neonates (≤28 days old) and 140 (55.1%) were male. In 139 infants >28 days old with borderline hypernatraemia, the mortality rate (n=9/139; 6.5%) was significantly higher than the mortality rate observed in infants without hypernatraemia (n=194/5 857; 3.3%) (OR 2.02; 95% CI 1.03 - 3.98).
Conclusion. Borderline hypernatraemia may be a risk factor associated with higher mortality in hospitalised infants. Prospective studies are required to determine whether borderline hypernatraemia contributes independently to mortality risk in hospitalised infants.
An audit of electronic discharge summaries of neonates admitted with hypoxic ischaemic encephalopathy to tertiary hospitals in [City], 2018–2019.
Authors: Afolabi K M , Van der Byl A , Joubert G 
Published: November 2023

Background. A discharge summary may be the only available health record for a patient, especially in resource-limited settings with suboptimal record-keeping. Considering the risk of adverse neurodevelopmental outcomes secondary to hypoxic ischaemic encephalopathy (HIE) and litigation, the quality of summaries for neonates with HIE is particularly important.
Objectives. To audit electronic discharge summaries of neonates admitted with HIE to two tertiary hospitals in [City], South Africa.
Methods. A retrospective, quantitative study was conducted. Electronic discharge summaries of late preterm and term neonates with HIE, admitted in 2018 and 2019 were audited for relevant information: final diagnosis, birth history, clinical evaluation, management, investigations, plan at discharge, and counselling of parents.
Results. Of the 165 identified cases, 34 (20.6%) were excluded. Ten patients did not have electronic discharge summaries. Details of the other 24 cases in admission registers were incomplete. The final diagnosis of HIE appeared in 87 (66.4%) of 131 audited summaries. More than half (52.7%) lacked correct ICD-10 coding for HIE. Information on foetal distress and sentinel events was absent in 61.1% and 42.0%. Requirement for resuscitation was recorded in 90.8% of summaries. Performance of cardiac compressions and adrenaline administration were not specified in 46.6% and 54.2%. Admission blood gas results, particularly base deficit, lactate and glucose, were absent in 42.7%, 63.4% and 90.8% of summaries. Eligibility for therapeutic hypothermia was not captured in 41.2%. Cranial ultrasound, neuro-imaging, exclusion of meningitis, or multisystem involvement was not mentioned in 80.9%, 99.2%, 80.2% and 96.2%, respectively. Notes on counselling of parents were lacking (83.2%). Final cause of death was unspecified in 12 of 14 (85.7%) patients who died.
Conclusion. Discharge summaries of neonates at risk of adverse neurodevelopmental outcomes secondary to HIE lacked essential information. Quality improvement and regular auditing of patient records must be prioritised.
Deliberative Mini-Publics as a Democratic Alternative: The Normative Desirability, Technical Feasibility, and Political Viability of Sortition
Authors: Solé Delgado Victoria 
Published: November 2023

Mini-públicos deliberativos como una alternativa democrática: la deseabilidad normativa, factibilidad técnica y viabilidad política del sorteo
Abstract: Democratic societies are currently facing a legitimacy crisis, as evidenced by citizens’ distrust towards political institutions and parties, as well as the emergence of anti-democratic responses. To address this crisis some civil society actors and scholars have proposed alternatives based on radical egalitarian principles that can be classified as “real utopias”. To overcome the contradiction between utopia and reality, these alternatives need to extend beyond what is considered normatively desirable and must also be both technically feasible and politically viable. This paper aims to analyze sortition and mini-publics as one of those alternatives.
Resumen: La emergencia de propuestas antidemocráticas y la desconfianza ciudadana hacia los partidos e instituciones políticas reflejan la crisis de legitimidad que atraviesan actualmente las sociedades democráticas. Para abordar esta crisis, algunos actores de la sociedad civil e investigadoras/es han propuesto alternativas basadas en principios igualitarios radicales que pueden ser clasificadas como “utopías reales”. Para superar la contradicción entre utopía y realidad, dichas alternativas deben extenderse más allá de lo normativamente deseable y deben ser también técnicamente factibles y políticamente viables. El objetivo del presente artículo es analizar el sorteo y los mini-públicos como una de esas alternativas.
Testing Open Science Tools
Authors: Viitanen Essi 
Published: November 2023

Data management plans (DMP) are an intrinsic part of planning for and implementing openness in scientific research. DMPs contain integral information on research projects: IT requirements, legal and ethical considerations and strategies for opening data. However, all too often, the DMP is seen as a chore drawn up at the request of external funders rather than a tool adopted for the benefit of project members. Similarly, the information gathered into DMPs is rarely utilised by other stakeholders such as institutional research services, nor linked to external parties such as data repositories.
Machine-actionable DMPs aim to change this landscape by offering better guidance and support for researchers preparing their plans, and facilitating a research data management system that allows data and information to be shared across institutions and repositories. In fact, one of the recommendations of the EOSC Nordic project, which studied FAIR incentives and expected impact in the Nordics, Baltics and EOSC, was the implementation of machine-actionable DMPs for seamless information workflow and supporting FAIR adoption in everyday research work.
Tools such as Data Stewardship Wizard and Argos do this by taking researchers through a set of simple structural questions on research data management from which answers are exported into funder templates resulting in downloadable DMP documents. These machine-actionable online tools transform tick-the-box answers that are easy to fill in into full-text DMPs that comply with funder requirements.
This poster introduces a pilot project testing the Data Stewardship Wizard and localising its Knowledge Template to the needs of Aalto University. It presents the project’s findings and stages, including the process of creating a template for the Research Council of Finland DMPs and testing the tool with researchers. In doing so, it examines machine-actionable DMPs from a practice-based perspective and comments on the process of institutional implementation.
Role of Pink1-mediated mitophagy in adenomyosis
Authors: Chen Minmin , Wang Wei , Fu Xianyun , Yi Yongli , Wang Kun , Wang Meiling 
Published: November 2023

Abstract Background
Recent studies indicate that endometrial hypoxia plays a critical role in adenomyosis (AM) development. Mitochondria are extremely sensitive to hypoxic damage, which can result in both morphological and functional impairment. Mitophagy is a crucial mechanism for preserving mitochondrial quality by selectively removing damaged mitochondria, thus ensuring the proper functioning of the entire mitochondrial network. In response to hypoxia, PINK1 is activated as a regulator of mitophagy, but its role in AM requires further study.

Objective
To explore the potential mechanism of mitophagy mediated by PINK1 in the pathogenesis of AM.

Method
The study compared PINK1, Parkin, OPTIN, P62, and NDP52 protein expression levels in patients with or without AM using clinical specimens and an AM mouse model. Pathological changes were compared using HE staining. Immunofluorescence and western blot were used to detect protein expression levels. Endometrial stromal cells (ESC) were isolated and examined for mitophagy, protein expression level, and cell invasion ability.

Results
Both the endometrial tissue from patients with AM and AM ESC displayed an upregulation of protein levels for PINK1, Parkin, OPTIN, P62, and NDP52 when compared with the control group. Then, HE staining confirmed the successful establishment of the AM mouse model. Moreover, the ultrastructural analysis using transmission electron microscopy revealed that AM mice’s endometrial glandular epithelial and stromal cells had exhibited swollen, deformed, and reduced mitochondria along with an increase in the number of lysosomes and mitochondrial autophagosomes. The protein levels of PINK1, Parkin, OPTIN, P62, and NDP52 in uterine tissue from AM mice were noticeably increased, accompanied by a considerable upregulation of ROS levels compared to the control group. In addition, cells in the AM group showed remarkably elevated mitophagy and invasion potentials compared to the control group. In contrast, the cell invasion ability decreased following PINK1 knockdown using the RNA interference technique.

Conclusion
The high levels of PINK1-mediated mitophagy have been found in AM. The upregulation in mitophagy contributes to mitochondrial damage, which may result in the abnormal invasion characteristic of AM.
Optimization of the Traditional Process of Oil Extraction from Sardine Viscera (Sardina pilchardus) in the Far North Region-Cameroon by the Response Surface Methodology
Authors: Chimi Bill Jaures , Ghomdim Horliane Nzali , Ngangoum Eric Serge , Djiazet Stève , Kapseu César , Tchiegang Clergé 
Published: November 2023

Aims: Sardina pilchardus is a fish highly found in rivers and lakes in the Far-North region of Cameroon. This work aimed at optimizing the traditional extraction parameters in order to improve the quality and yield of oil.
Methodology: A central composite design was used to study the effect of processing (cooking time, viscera/water ratio and settling time) on the extraction yield and quality of oil. The yield and quality of the oil obtained were compared to the traditional extraction method.
Results: It appears that the cooking and the settling times increased the extraction yield. The cooking time, the viscera/water ratio and their interactions reduced the acid value. The viscera/water ratio contributed to the reduction of the peroxide value. Optimal condition was found to be at cooking time of 17.02min, viscera/water ratio of 100:152.86g/mL, settling time of 95.59 min, at the temperature of 95°C. The optimized processing conditions improved the extraction yield by 10 to 25%, an increase of 2.3 times compared to the traditional process and preserved the quality of the oil (acid value of 1.35 mg KOH /g oil and peroxide value of 1.20 meq O₂/kg oil).
Conclusion: The relationship between the actual and predicted data indicates that the response model was adequate to reflect the expected optimization. This will therefore help fish oil producers in the Far North region of Cameroon.
Effectiveness of Readers Theatre to Enhance English Reading Fluency in Fifth Grade: Action Research in Thrimshing Higher Secondary School
Authors: Kelzang  , Tshering Ngajay , Tshering Tsheten , Tshering Dendup 
Published: November 2023

Researchers have identified the reading problem in the rural schools in Bhutan, and students hardly read English text. Therefore, researchers have resolved to conduct action research study to investigates the effectiveness of Readers Theatre as an intervention strategy to enhance reading fluency and motivation among fifth-grade students in the school. The researchers identified a decline in reading habits and fluency among students, particularly in English, despite recognizing the importance of reading for academic success and personal development.
A mixed-method design was employed, combining quantitative data collection through pre- and post-tests with qualitative insights from structured interviews from 24 participants. To enhance the reading fluency, Readers Theatre approach was integrated into exploring its potential impact on motivation and fluency.
The results indicate significant improvements in reading fluency among participants after the intervention, with many exceeding expectations. Qualitative data revealed that Readers Theatre not only improved reading skills but also engendered enthusiasm and confidence in reading. This study highlights the critical role of motivation in successful reading interventions, emphasising that motivated readers are more likely to become proficient ones. The findings underscore the importance of innovative and engaging reading strategies in fostering reading fluency and motivation. This research offers valuable insights for educators and policymakers, advocating for the adoption of such strategies to empower students with essential reading skills and cultivate a lifelong love for learning.
Phytochemical Analysis and Antimicrobial Screening of Artocarpus altilis: Guyana Flora Extracts
Authors: Tewari Brij Bhushan 
Published: November 2023

The plant material leaves of Artocarpus altilis (Breadfruit) were collected from university of Guyana road, Cummings lodge, Guyana. Leaves were dried in oven at 50-55 ºC for 72 h. The moisture content is calculated. The dried leaves were grounded and extracted in each acetone, ethanol and methanol solvents. Extracts were collected and evaporation of solvent was done on rotavapour. The respective solvent was added to viscous semi solid liquid extract to make up the desired volume of extract solution. The antimicrobial and antifungal activity of both plants were examined by well diffusion method, poison plate method, paper disc plate method and streak plate methods. In Artocarpus altilis leaves extract studies, maximum and minimum antimicrobial potential was observed for methanol and acetone solvent extracts, respectively. All plant extracts showed antimicrobial potential toward the organisms Staphylococcus aureus, Escherichia coli and Candida albicans. The phytochemical analysis of methanol leaves extract of breadfruit tested positive for flavonoids, terpinoids, phenol, phlobatannins, steroids and phytosteroids and negative for tannins, saponins , alkaloids and cardiac glycosides.
Optimum Sowing Window and Suitable Varieties for Cultivation Soybean (Glycine max L.) During Off-Season in Northern Telangana Zone
Authors: Mounika, U.  , Balaji Naik, B.  , Ramanjaneyulu, A. V.  , Pavan Chandra Reddy, K.  
Published: November 2023

Aims: To identify the optimum sowing time and suitable varieties of soybean for profitable cultivation during the off-season in the Northern Telangana Agroclimatic zone of Telangana state in India.
Study Design: Strip plot design with three replications.
Place and Duration of Study: The Regional Sugarcane and Rice Research Station, Professor Jayashankar Telangana State Agricultural University (PJTSAU), Rudrur, Nizamabad District, Telangana state, India, between October 2022 and June 2023.
Methodology: The field experiment was conducted in medium clay loam soil under irrigated condition. The experiment was laid out in strip plot design with three varieties viz., JS 335 (V1), ASB 22 (V2) and KDS 726 (V3) as horizontal strips and nine dates of sowings viz., 3 Oct (D1), 19 Oct (D2), 3 Nov (D3), 19 Nov (D4), 3 Dec (D5) 19 Dec (D6), 3 Jan (D7), 19 Jan (D8) and 3 Feb (D9) as vertical strips, replicated thrice. The seeds were sown by dibbling at 5 cm apart within the row and rows were space at 45 cm apart. Standard recommended package of practice of kharif season suggested by PJTSAU was followed. The data on growth yield attributes was recorded on selected 5 plant, averaged/ plant and grain yield was recorded from net plot, converted to one hectare and analyzed statistically using OP Stat.
Results: The results of the experiment revealed that, the cv. KDS 726 recorded the maximum plant height (35.2 cm) and biomass accumulation (8.93 g plant-1) which was significantly more over the cv. JS 335 and cv. ASB 22 in 3 Nov and 19 Oct sowings, respectively. The cultivars the cv. JS 335 (V1) recorded more number of pods over cv. ASB 22 (V2) and cv. KDS 726 (V3) in 19 Oct (D2), 3 Nov (D3), 19 Nov (D4), 3 Dec (D5) and 3 Jan (D7) sowings. The cv. KDS 726 (V3) was found superior in terms of seeds pod -1 (3.0) which was comparable to cv. JS 335 (V1) and significantly more over cv. ASB 22 (V2) when it was sown on 19 Oct (D2). The cv. KDS 726 (V3) recorded significantly more test weight (g) over cv. JS 335 (V1) and cv. ASB 22 (V2) from 19 Oct (D2) to 3 Jan (D7) sowings. The cv. ASB 22 sown on 3 Oct produced significantly more seed yield (753 kg ha-1) and haulm yield (1599 kg ha-1) over cv. JS 335 and cv. (KDS 726).
Conclusion: The soybean cv. ASB 22 with sowing first week of Oct was found to be suitable for cultivation during the off season.