bluuebunny/crossref_metadata_2025_split huggingface dataset:
The interaction of post-activation potentiation and fatigue on skeletal muscle twitch torque and displacement
Authors: Langen Georg , Warschun Frank , Ueberschär Olaf , Behringer Michael 
Published: January 2025

IntroductionTensiomyography (TMG) assesses skeletal muscle contractile properties based on the electrically stimulated radial muscle displacement. As the relationship between twitch displacement and associated torque is poorly understood, it is unclear how it is affected by post-activation potentiation and muscle fatigue. This study investigated how the interaction of potentiation and fatigue affects the rectus femoris (RF) twitch displacement and associated torque.Materials and methodsSixteen resistance-trained men (n = 8) and women (n = 8) performed two sets of five and five sets of ten seated maximum voluntary isometric knee extensions to induce potentiation and fatigue. Twitch displacement and torque were measured at baseline before the first set, after each set, and every 2 min for 15 min after the last set.ResultsThe exercise effectively induced potentiation and fatigue as peak twitch torque increased by 44.1% after the first set, decreased by 32.9% after the last set and remained decreased by 26.4% after 15 min. Twitch displacement was considerably less affected by the exercise. Consequently, TMG parameters could not accurately detect potentiated or fatigued participants as indicated by the peak twitch torque.DiscussionThe TMG parameters’ insufficient diagnostic accuracy likely resulted from a reduced signal-to-noise ratio at 90° knee flexion and the associated longer muscle length of the RF, compared to more extended knee angles commonly employed in TMG studies. These results highlight an important methodological consideration as the joint angle, i.e. muscle length, appears to influence the TMG parameters’ ability to detect exercise-induced changes in contractile properties.
Optimized measurement methods and systems for the dielectric properties of active biological tissues in the 10Hz-100 MHz frequency range
Authors: Shi Yueying , Bai Xiaoxiao , Yang Jingrong , Wu Xinyu , Wang Lei 
Published: January 2025

The dielectric properties of active biological tissues within the 10Hz-100 MHz frequency range contain rich information about tissue morphology and function. Accurately understanding the dielectric properties of active human tissues holds significant value for disease diagnosis and electromagnetic protection. However, accurately measuring these properties has been challenging due to factors such as electrode polarization and distribution parameters. This study has developed a dual-purpose measuring cell that supports both four-electrode and two-electrode impedance measurements. Leveraging this development, we have established a system and methodology that is well-suited for the dielectric property measurement of active biological tissues within the frequency range of 10Hz to 100 MHz. Our measurements of dielectric properties in NaCl solutions of varying concentrations and pig liver tissues demonstrate the system’s high accuracy and repeatability. For NaCl solutions, the maximum relative deviation is only 6.34%, with an average deviation of less than 1.5%. For pig liver tissues, the overall relative deviation is below 6%. Through the integration of the four-electrode and two-electrode measurement systems, we have successfully addressed the challenges of electrode polarization at low frequencies and the influence of distribution parameters at high frequencies, achieving a significant improvement in measurement accuracy across the spectrum.
Phloem cell responses to the feeding activity of Eriosoma lanigerum on Malus domestica
Authors: Nogueira Ravena Malheiros , Bragança Gracielle Pimenta Pereira , Picoli Edgard Augusto de Toledo , de Oliveira Denis Coelho , Isaias Rosy Mary dos Santos 
Published: January 2025

IntroductionHemipteran gall vascular traits result from the access, piercing, and sucking of the inducer mouth parts directly in the xylem and phloem conductive cells. Herein, our focus relies on mapping the features of phloem cells in the proximal, median, and distal regions of Malus pumila stem galls and adjacent galled stems.MethodsPhloem cells were dissociated from gall fragments, the stem portions above and below the galls, and the proximal and distal regions of M. pumila stem galls. were measured. The comparison of the higher length and diameter of the sieve tube elements (STE) was evaluated considering the priority of nutrient flow to gall portions.ResultsIn the M. pumila - E. lanigerum system, there were no significant differences in the dimensions of the STE in the galls compared with those of the stem portions above and below the galls.DiscussionAt the cytological level, the callose deposited in gall STE and the decrease in the cell lumen area in the stem portion above the gall due to thickened nacreous cell walls have implications for nutrient flow. Peculiarly, the smaller sieve pores in the sieve plates of the STE located in the galls and stem portions above and below them and the deposition of P-protein in the stem portions below the galls limit the bidirectional transport of nutrients, benefiting the transport of photoassimilates to the gall proximal region and reducing the vigor of apple tree stems.
Latent profile analysis and influence factors study of nurses’ job performance
Authors: Liu Zhenfan , Yan Xiaoting , Xie Guifang , Lu Jing , Wang Zhitong , Chen Cui , Wu Jijun , Qing Wei 
Published: January 2025

ObjectiveTo investigate the current status of nurses’ job performance, to analyze the latent profile analysis of nurses’ job performance and their relationship with occupational coping self-efficacy, perceived social support and to explore the factors influencing the different profiles.MethodsFrom April to June 2024, 390 nurses from five general hospitals were facilitated to be selected as survey respondents using a general information questionnaire, job performance scale, occupational coping self-efficacy scale, and perceived social support scale. Latent profile analysis of nurses’ job performance were analyzed, and logistic regression was used to analyze the factors influencing different categories of nurses’ job performance.Results390 nurses were finally included. Nurses job performance score was (45.05 ± 6.55). Nurses’ job performance could be categorized into three latent profile analysis: low job performance (13.9%), medium job performance (52.8%) and high job performance (33.3%). Logistic regression analysis showed that years of working experience, form of employment, perceived social support and occupational coping self-efficacy were the influencing factors of nurses’ job performance (all p &lt; 0.05).ConclusionNurses’ job performance is moderate to high and heterogeneous. Nursing managers should focus on “low job performance” and “medium job performance” nurses, and intervene and support nurses according to the characteristics and influencing factors of the different categories in order to improve their performance.
Effect of the Big Five Personality on the intention to use mHealth applications among the Chinese elderly: a national-based study
Authors: Chang Jinghui , Li Anqi , Yang Xixi , Li Chunnan , Mai Yanshan , Zhang Dayi , Yan Wende , Wu Yibo , Chen Jiangyun 
Published: January 2025

BackgroundMobile health applications may provide potential tools to support healthy aging. Promoting mHealth use by the elderly remains an imperative to realize health improvement.ObjectiveThe research aimed to identify the relationship between personality traits and the intention to use mHealth applications among the elderly in mainland China.MethodsUsing a multi-stage sampling method, a cross-sectional survey of 3,712 older adults across China was obtained out of 3,721 (validity rate was 99.76%) in 2022. The effect of personality on the intention to use mHealth applications among older adults was analyzed by multiple linear regression. The independent variable was the personality, using the short version of the Big Five Personality Inventory (BFI-10). The dependent variable was the intention to use the mHealth applications, measured using a sliding scale. Moderators included demographic characteristics and psycho-social variables measured by the Perceived Social Support Scale, the Family Health Scale, and the Health Literacy Scale.ResultsThe Chinese older adults’ intention to use mHealth applications scored (63.31 ± 25.09). Out of the five traits, extraversion, agreeableness, and openness exerted significant effects. Higher scores of extraversion (β=0.59, t = 1.99, p<0.05) and openness (β=1.87, t = 6.07, p<0.01) contributed to the intention to use mHealth applications. Conversely, higher agreeableness scores (β= − 1.05, t = −3.12, p<0.01) related to lower intention.ConclusionThe elderly with high extraversion, openness, and low agreeableness are more willing to adopt mHealth applications in China. Healthcare professionals and mHealth device developers can make personalized and accurate interventions for the elderly with different personalities.
The relationship between academic passions and critical thinking in a Chinese college student sample: a latent profile analysis
Authors: Wang Shaojie , Fan Xizhen , Yu Hao , Yan Xing , Wang Jianmei , Liu Ying , Li Yue 
Published: January 2025

BackgroundAcademic passions, including harmonious and obsessive passions, play a significant role in academic life by influencing students’ motivation, engagement, and overall academic success. Critical thinking is essential in education as it helps individuals assess, evaluate, and make informed decisions based on reasoning, which is crucial for academic growth and lifelong learning. Given the increasing emphasis on developing critical thinking skills in education, it is crucial to investigate how academic passions influence this cognitive process in the Chinese context.MethodsA total of 698 valid questionnaires were collected from college students from Guangdong and Hunan provinces in China. This study used latent profile analysis (LPA) to investigate the profiles of harmonious and obsessive passions. Then it tested differences in critical thinking based on the profiles of harmonious and obsessive passions.ResultsThree latent profiles for two academic passions were identified: low, medium, and high. Respondents in the high harmonious and obsessive passion profiles exhibited the significantly highest critical thinking abilities.ConclusionThe results confirm the heterogeneity of harmonious and obsessive passions. Students with higher levels of academic passions demonstrate enhanced critical thinking abilities compared to their peers. This study suggests that educators should pay attention to students’ academic passions when cultivating their critical thinking skills. This study offers several implications for practice. First, colleges should provide targeted counseling and guidance based on the types of students’ passion. Second, it is necessary to balance the relationship between harmonious and obsessive passions to promote students’ mental health and academic persistence. Third, colleges should help students develop harmonious passion, thereby improving their critical thinking ability.
Acceptability and efficacy of the culturally adapted problem management plus intervention for people with disability in Pakistan: a pilot cluster randomized controlled trial
Authors: Hussain Basharat , Khalily Muhammad Tahir , Waqas Ahmed , Rahman Atif , Angelakis Ioannis , Nisar Anum , Zaman Sabir , Akhtar Tanveer 
Published: January 2025

BackgroundIn Pakistan, the mental health care for persons living with disabilities is insufficient, lacking a holistic approach to address their needs. This research evaluates the adapted PM+’s (IA-PM+) initial efficacy and acceptability in improving mental health among persons living with disabilities, contributing to the integration of mental health services within primary care settings in Pakistan.MethodsThis study employed a two-arm, single-blind cluster randomized controlled trial in a community setting within Union Council Kuri Dolal, Tehsil Gujjar Khan, District Rawalpindi-Pakistan. It compared an Active Treatment group, receiving five sessions of the IA-PM+ intervention, against a Delayed Treatment Control group. A total of 148 participants were randomized. Randomization occurred at the village level, with clusters assigned to either the intervention or control group. The intervention’s effectiveness and participant satisfaction were assessed using a variety of measures, including the GHQ-12, WHODAS 2.0, DASS-21, and the Client Satisfaction Questionnaire, at baseline, the 8th week, and during a 3-month follow-up. Qualitative feedback was gathered at the end of the study to assess the intervention’s acceptability among the participants.ResultsThe study achieved a 100% retention rate. Baseline demographics showed a majority male participation with a variety of disabilities predominantly lower limb. Significant improvements were noted in the intervention group across WHODAS scores (Cohen’s d= 0.66), PTSD symptoms (d= 0.75), and DASS scores for depression (d= 0.46), anxiety (d=0.65), and stress (d= 0.47). Similar trends were noted during the follow-up phases. However, life satisfaction scores initially higher in the control group evened out by follow-up, and perceived social support was consistently lower in the intervention group. High levels of client satisfaction were reported in the intervention group, with most participants finding the sessions beneficial and expressing willingness to recommend the service to others. The qualitative interviews revealed that the integration of religious practices, such as associating stress management techniques with Adhan, significantly enhanced the acceptability of the culturally adapted PM+ intervention. Participants reported that this cultural alignment made the coping strategies more relatable and easier to adopt, contributing to improvements in both their mental health and somatic symptoms.Clinical Trial Registrationhttps://clinicaltrials.gov/ct2/show/NCT04981522, identifier NCT04981522.
Factorial invariance of the generalized anxiety disorder scale (GAD-7) in Latin America and the Caribbean
Authors: López Norman , Coronado Juan-Carlos , Ripoll-Córdoba Daniela , Caldichoury Nicole , Quispe-Ayala César , Morales-Asencio Breiner , Quincho-Apumayta Raúl , Castellanos Cesar , Martínez Juan , Cárdenas-Valverde Juan , Castellanos-Alvarenga Luis Mario , Salazar David , Flores-Poma Irina , Herrera-Pino Jorge , Bada Wendy , Flórez Yuliana , Alcos-Flores Karen , Zurita-Cueva Boris , Muñoz Romero Elsa , Romo Cristian , Antezana Regulo , Avila Saldaña Claudio , Gargiulo Pascual A. 
Published: January 2025

IntroductionThe prevalence of Generalized Anxiety Disorder (GAD) has increased rapidly, highlighting the importance of its detection using quick tools applicable to men and women from different countries.ObjectiveTo analyze the psychometric properties of the Generalized Anxiety Disorder Test (GAD-7) by gender and country in Latin America and the Caribbean (LAC).MethodA cross-sectional e-health study with 12,124 participants from 15 LAC countries (54.32% women, 45.68% men) was conducted, including participants from Argentina (7.3%), Bolivia (6.7%), Colombia (10.3%), Chile (6.9%), Costa Rica (4.9%), El Salvador (5.7%), Ecuador (7.2%), Guatemala (4.7%), Panama (5.1%), Paraguay (5.7%), Peru (8.6%), Puerto Rico (5.8%), the Dominican Republic (6.6%), Uruguay (6.3%), and Venezuela (8.2%). All participants completed the GAD-7 scale digitally.ResultsA unidimensional structure of the GAD-7 was confirmed, explaining 70% of the variance. The model fit indices were adequate (RMSEA = 0.062; CFI = 0.997; TLI = 0.995; SRMR = 0.017; p &lt; 0.001), and the factor loadings for each item were satisfactory (&gt; 0.70). Additionally, the factor structure showed measurement invariance between genders and countries, with adequate fit indices at all levels (configural, metric, scalar, and strict), suggesting that the measurements are equivalent in both contexts. Finally, the internal consistency of the GAD-7 was high, with a McDonald’s Omega coefficient of 0.91.ConclusionsThe GAD-7 exhibits a factor structure that is equivalent across genders and countries, demonstrating its validity and reliability for the rapid detection of GAD symptoms in different countries within the region.
Parsing the heterogeneity of depression: a data-driven subgroup derived from cognitive function
Authors: Xu Chenyang , Tao Yanbao , Lin Yunhan , Zhu Jiahui , Li Zhuoran , Li Jiayi , Wang Mingqia , Huang Tao , Shi Chuan 
Published: January 2025

BackgroundIncreasing evidences suggests that depression is a heterogeneous clinical syndrome. Cognitive deficits in depression are associated with poor psychosocial functioning and worse response to conventional antidepressants. However, a consistent profile of neurocognitive abnormalities in depression remains unclear.ObjectiveWe used data-driven parsing of cognitive performance to reveal subgroups present across depressed individuals and then investigate the change pattern of cognitive subgroups across the course in follow-up.MethodWe assessed cognition in 163 patients with depression using The Chinese Brief Cognitive Test(C-BCT) and the scores were compared with those of 196 healthy controls (HCs). 58 patients were reassessed after 8 weeks. We used K-means cluster analysis to identify cognitive subgroups, and compared clinical variables among these subgroups. A linear mixed-effects model, incorporating time and group (with interaction term: time × group) as fixed effects, was used to assess cognitive changes over time. Stepwise logistic regression analysis was conducted to identify risk factors associated with these subgroups.ResultsTwo distinct neurocognitive subgroups were identified: (1) a cognitive-impaired subgroup with global impairment across all domains assessed by the C-BCT, and (2) a cognitive-preserved subgroup, exhibited intact cognitive function, with performance well within the healthy range. The cognitive-impaired subgroup presented with more severe baseline symptoms, including depressed mood, guilt, suicidality, and poorer work performance. Significant group × time interactions were observed in the Trail Making Test Part A (TMT-A) and Continuous Performance Test (CPT), but not in Symbol Coding or Digit Span tests. Despite partial improvement in TMT-A and CPT tests, the cognitive-impaired subgroup's scores remained lower than those of the cognitive-preserved subgroup across all tests at the study endpoint. Multiple regression analysis indicated that longer illness duration, lower educational levels, and antipsychotic medication use may be risk factors for cognitive impairment.ConclusionThis study identifies distinguishable cognitive subgroups in acute depression, thereby confirming the presence of cognitive heterogeneity. The cognitive-impaired subgroup exhibits distinct symptoms and persistent cognitive deficits even after treatment. Screening for cognitive dysfunction may facilitate more targeted interventions.Clinical Trial Registrationhttps://www.chictr.org, identifier ChiCTR2400092796.
Digital integration between hospitals and local health authorities for enhanced vaccination coverage among frail patients: the CareVax study protocol
Authors: Lontano Alberto , Regazzi Luca , Tona Diego Maria , Di Pumpo Matteo , Porcelli Martina , Cacciuttolo Maria Gabriella , Parente Paolo , Gasbarrini Antonio , Grandaliano Giuseppe , Panocchia Nicola , Lopetuso Loris , Pasciuto Tina , Cadeddu Chiara , Bruno Stefania , Laurenti Patrizia , Pascucci Domenico , Pastorino Roberta 
Published: January 2025

BackgroundThe 2022–2025 Italian Plan for vaccine prevention (PNPV), recognizes vaccine-preventable diseases (VPDs) as significant contributors to mortality, morbidity, and healthcare expenditure. The digitalization of the national vaccine registry is underway. Initiatives aimed at enhancing digital integration between hospitals and territories are limited, and there is still a gap in the development of automated systems for identifying patients who could benefit from vaccinations directly offered from hospitals.MethodsAdult frail patients who access the hospital will be recruited over 4 years, following the acquisition of informed consent. With the assistance of a privacy-preserving automated algorithm, electronic hospital and vaccination records will be utilized to assess eligibility for vaccinations against SARS-CoV-2, Herpes Zoster, Influenza, Streptococcus pneumoniae, and Hepatitis B. Eligible patients will be invited to schedule a vaccination appointment and will be asked to fill in a questionnaire evaluating patient-reported experience measures (PREMs). Outcomes of interest are the feasibility of the pathway, patients’ satisfaction and concerns with it, and its impact on vaccination coverage.Ethics and disseminationThe study has been approved by the ethics committee of the “Fondazione Policlinico Universitario Agostino Gemelli” -FPG- (comitato.etico@policlinicogemelli.it), with approval number 5819. Furthermore, it has been published on ClinicalTrial.gov with the approval number NCT06127563. The results of the study will be disseminated via conference presentations and peer-reviewed publications.Clinical trial registrationClinicalTrials.gov, identifier NCT06127563.
Association between ethylene oxide exposure and osteoarthritis risk: an analysis of NHANES data (2013–2014 and 2017–2018)
Authors: Li Zhongshan , Qu Qi , Wang Zhiyu , Mou Shuanglin , Jiang Rui , Zhu Wensheng 
Published: January 2025

BackgroundEthylene oxide (EO) is widely used as a disinfectant and is also a common environmental pollutant. Exposure to EO has been associated with various systemic diseases, posing crucial health risks. However, EO is frequently employed as a sterilizing agent in orthopedics, while its association with the risk of skeletal system diseases remains insufficiently evaluated. This study aims to investigate the association between EO exposure and the risk of Osteoarthritis (OA), a prevalent orthopedic condition.MethodsA total of 3,386 participants were selected from the National Health and Nutrition Examination Survey (NHANES) 2013–2014 and 2017–2018 cycles, including 952 individuals with OA. Box plots assessed EO concentration differences between OA and non-OA groups. Weighted logistic regression models and restricted cubic spline (RCS) models were used to evaluate the relationship between EO exposure and OA risk. Subgroup analysis and interaction test explored variations in the association across different characteristics.ResultsNo significant difference in EO concentrations was found between OA and non-OA groups. In multivariate logistic regression, high EO level exposure was significantly associated with increased OA risk. Additionally, a nonlinear U-shaped and J-shaped association was observed in the unadjusted and adjusted RCS models, respectively. Subgroup analysis revealed that the association between EO exposure and OA risk was more pronounced in the 20–40 and 40–65 age groups, never smokers (Not at all), and those with low calcium levels (&lt; 8.5 mg/dL) or low vitamin D levels (&lt; 75 nmol/L).ConclusionsEO exposure is associated with OA risk, exhibiting a J-shaped relationship, with this association being particularly pronounced in individuals under 65 years old or those with low calcium or vitamin D levels. Further prospective studies are needed to examine the association between EO exposure and OA risk.