bluuebunny/crossref_metadata_2025_split huggingface dataset:
La reine du crime. Jeu et… fin de partie
Authors: Driant Anouk 
Published: October 2023

L’article propose d’explorer les sublimations dans l’œuvre d’Agatha Christie dont on connaît le succès retentissant. Dans sa très longue autobiographie, nous la voyons tenter de transformer par tous les moyens (jeu, écriture, pulsion d’investigation) une enfance pourtant non exempte de manques, de blessures, de traumatismes, auxquels répondront pas moins de soixante-six crime novels, dans lesquelles le mal banal intrafamilial est partout, et le meurtre premier. Christie entraînera chaque fois son lecteur dans une enquête passionnante et excitante, résolue par ses célèbres détectives (Hercule Poirot et Miss Marple). Son plaisir à écrire et sa réussite d’écrivaine ne pourront cependant pas la protéger d’un épisode clinique grave lorsqu’en 1926, elle disparaît onze jours, souffrant d’un moment de psychose hystérique, recouvert par le silence d’une amnésie totale.
Prendre goût à la politique : la construction de la communauté de Sant’Egidio dans le « long 1968 » italien (1967-1978)
Authors: Balas Marie 
Published: October 2023

Organisation catholique aujourd’hui influente sur les plans ecclésial et international, la communauté de Sant’Egidio fut fondée à Rome en 1968, et s’est consolidée durant la décennie de mobilisation qui s’ensuivit. Rassemblant diverses sources de la période, cet article s’efforce d’en reconstituer la trajectoire intellectuelle et militante durant ce « lungo ‘68 ». À distance d’une histoire autorisée relativement dépolitisée, l’étude prête attention aux modèles d’inspiration du groupe, à ses répertoires d’action et à son travail de cadrage. Elle s’attarde sur deux moments : d’une part le « moment 1968 », fondateur pour la communauté et sa politisation, et d’autre part l’explosion de la contestation en 1977-1978, qui précéda l’effondrement de la mobilisation. Il s’agit d’élucider la manière dont un collectif catholique engagé dans les combats de la décennie, non seulement survécut à la crise du militantisme, mais en ressortit outillé et en voie de multipositionnement.
Introduction
Authors: Laville Béatrice , Partensky Vérane 
Published: October 2023

À une époque marquée par l’essor du capitalisme l’économie impose également ses perspectives d’analyse à la littérature et accompagne le discours du réalisme naissant. L’article étudie l’attitude ambivalente des Goncourt face aux contraintes de l’économie moderne : attaché à l’utopie d’une aristocratie des Lettres, ils affirment la possibilité de soustraire l’art et la littérature aux lois du marché, mais décrivent, dans leurs romans, la manière dont le système économique corrompt les relations sociales, dégrade les individus ou les broie.
NOVEL MUTATIONS IN THE NON-STRUCTURE PROTEIN 2 OF SARS-CoV-2
Authors: Nakhaei Mohsen , Ghoreshi Zohreh-Al-Sadat , Rezaei Zadeh Rukerd Mohammad , Askarpour Hedyeh , Nasir  
Published: October 2023

Background: Mutation in the genome of SARS-CoV-2 may play a role in immune evasion, pathogenicity and speed of its transmission. Our investigation aimed to evaluate the mutations that exist in the nsp2.
Materials and Method: RNA was extracted from nasopharyngeal swabs from 100 COVID-19 patients. RT-PCR was performed on all samples using nsp2 specific primers. Following gel electrophoresis, the bands were cut, purified, and sequenced using Sanger method. After sequencing, 90 sequences could be used for further analysis. Bioinformatics analysis was conducted to investigate the effect of mutations on protein structure, prediction of homology models, phylogeny tree.
Results: The patients' mean age wa
Background: Mutation in the genome of SARS-CoV-2 may play a role in immune evasion, pathogenicity and speed of its transmission. Our investigation aimed to evaluate the mutations that exist in the nsp2.
Materials and Method: RNA was extracted from nasopharyngeal swabs from 100 COVID-19 patients. RT-PCR was performed on all samples using nsp2 specific primers. Following gel electrophoresis, the bands were cut, purified, and sequenced using Sanger method. After sequencing, 90 sequences could be used for further analysis. Bioinformatics analysis was conducted to investigate the effect of mutations on protein structure, prediction of homology models, phylogeny tree.
Results: The patients' mean age was 51.08. The results revealed that 8 of the 17 nsp2 mutations (R207C, T224I, G262V, T265I, K337D, N348S, G392D, and I431M) were missense. One deletion was also found in nsp2. Among nsp2 missense mutations studied, K337D and G392D increased structural stability while the others decreased it. The homology-designed models demonstrated that the homologies were comparable to the sequences of the Wuhan-HU-1 virus.
Conclusion: Our study suggested that the mutations as K337D and G392D modulate the stability of nsp2 and tracking viral evolution should be implemented and vaccine development updated.
s 51.08. The results revealed that 8 of the 17 nsp2 mutations (R207C, T224I, G262V, T265I, K337D, N348S, G392D, and I431M) were missense. One deletion was also found in nsp2. Among nsp2 missense mutations studied, K337D and G392D increased structural stability while the others decreased it. The homology-designed models demonstrated that the homologies were comparable to the sequences of the Wuhan-HU-1 virus.
Conclusion: Our study suggested that the mutations as K337D and G392D modulate the stability of nsp2 and tracking viral evolution should be implemented and vaccine development updated.
LIVER DISEASE & SICKLE CELL DISEASE: AUTOIMMUNE HEPATITIS MORE THAN A COINCIDENCE; A SYSTEMATIC LITERATURE REVIEW.
Authors: Lynch Kelvin , Mega Andrea , Piccin Andrea , Daves Massimo , Fogarty Helen 
Published: October 2023

In patients with SCD, chronic liver damage is a common manifestation. More than 50% of SCD patients have elevated liver enzymes. Common underlying aetiologies include sickle cell hepatic crisis, viral hepatitis, sickle cell intrahepatic cholestasis and hepatic sequestration in the acute setting, and cholelithiasis and iron overload in the chronic setting. Autoimmune hepatitis (AIH) is a rare disease that appears to occur more commonly in the sickle cell disease (SCD) population than in the general population. There are many schools of thought as to why this is the case, including the phosphatidylserine hypothesis, the heme inflammatory hypothesis, the complement generation hypothesis, and the transfusion alloimmunization hypothesis.

Due to the natural history of the two illnesses, SCD is almost always diagnosed first in cases of dual pathology. Symptoms such as jaundice, fatigue, and abdominal pain are common in SCD, as are abnormal liver function tests (LFTs). These abnormalities, attributed to the other more frequent liver involvements in SCD, can lead to delays in AIH diagnosis in this population.
Corticosteroids, sometimes with other immunosuppressive agents, such as azathioprine, are the cornerstone of acute AIH treatment (4). However, corticosteroid use in the SCD population has been shown to carry an increased risk of vaso-occlusive crises (1, 5), providing a treatment dilemma.

The following is a review of AIH in the SCD population, where we explore the pathophysiology behind the association between the two disorders, discuss an approach to investigating abnormal LFTs in SCD, and examine treatment options in this population with co-existing diseases.
Factors Associated with Deterioration in Quality of Life of Subjects after Maxillofacial Fractures - A Prospective Study
Authors: Adetayo Adekunle Moses , Somoye Mayowa Solomon , Fasesan Oluwatoyin Adetutu , Oyedele Ayodeji Titus , Adetayo Modupe Olusola 
Published: October 2023

Abstract

Introduction:
Maxillofacial fractures (MFs) are quite common and are managed by oral and maxillofacial surgeons. Despite these interventions, a pre-traumatic facial profile is often not achieved with consequent social and psychologic consequences.

Materials and Methods:
Patients with fractures to the middle and lower third of the face that presented within 48 hours and healthy controls (subjects without facial fracture) that were sex- and age-matched with the fracture patients were recruited into the study. World Health Organization Quality of Life - Brief Version (WHOQOL-BREF) questionnaire was used to compare the Quality of Life (QoL) values according to age, gender, educational status, employment status, marital status, site of trauma and type of fracture.

Results:
Only the age of subjects was associated with deterioration in QoL after MF while other variables were not.

Discussion:
Increasing age of the patients was associated with higher QoL possibly because those with age <30 years are single and unemployed and may have fear and anxiety that the fracture could affect their chances of getting married or being employed, causing reduced QoL. Psychosocial rehabilitation is very important in patients with MF, especially for the young age group.
Religious Beliefs and Indeterminate Boundaries of Psychiatry
Authors: Singh Shipra 
Published: October 2023

Abstract
Defining normalcy in psychiatry is difficult. It depends on numerous factors such as social and cultural and may even vary for the same individual at different points in time. The dilemma arises when the behavior of person changes, but could not be classified as a disorder. Here, we describe the case of a young male, who became excessively inclined to religion. He presented with social withdrawal and frequent absenteeism from college. No clear affective or psychotic symptoms could be elicited. In consequent visits, he mentioned a recent interest in watching videos of religious leaders to understand “Allah” better. He started reading Quraan and following practices, unlike earlier. No psychiatric diagnosis could be made, thus appeared the issue of management. An eclectic model of therapy was used, with some success. To conclude, psychiatry is an enigmatic branch with obscure boundaries and gray areas. The involvement of religion is one such instance, which makes diagnosis and management challenging for the therapist. There is a need for adequate training pertaining to cultural knowledge and religious or spiritual context to psychiatry trainees, helping to attain confidence in better handling such issues.
The mediating role of body image concern in the relationship between immature defense mechanisms and postpartum depression in Iranian women
Authors: Shakib Haji Agha Rana , Kachooei Mohsen 
Published: October 2023

BACKGROUND:
Postpartum depression leaves irredeemable impacts on a mother's mental health and her child. Little is known about the relationship between immature defense mechanisms and body image concerns or postpartum depression. The present study examines the mediating role of body image concerns in the relationship between immature defense mechanisms and postpartum depression.

MATERIALS AND METHODS:
In a correlational study, 227 women were selected through a convenience sampling method from all women in the postpartum period in medical centers in 2021 in Tehran, Iran. The participants were asked to fill out the Edinburgh Postnatal Depression Scale (EPDS), the Defense Style Questionnaire-40 (DSQ-40) by Andrews et al., and the Body Image Concern Inventory (BICI). The collected data was analyzed using the IBM SPSS Amos 24 and SPSS 21 software.

RESULTS:
There was a positive correlation between body image concern, immature defense mechanisms, and postpartum depression. Furthermore, body image concern was a mediator in the relationship between immature defense mechanisms and postpartum depression. The immature defense mechanisms had an indirect positive impact on depression due to the concerns over one's body image after giving birth (P > 0.05).

CONCLUSION:
Immature defense mechanisms and body image concerns can increase the risk of postpartum depression. Therefore, providing mental health and psychiatric services to expecting mothers is an effective tool to decrease the activation of immature defense mechanisms, which would reduce their body image concerns and prevent them from falling into postpartum depression.
Development and validation of the clinical information literacy questionnaire
Authors: Maleki Elahe , Soleymani Mohammad R. , Ashrafi-Rizi Hasan , Heidari Zahra , Nasr-Esfahani Mohammad 
Published: October 2023

BACKGROUND:
Clinical Information Literacy (CIL) seems to be a prerequisite for physicians to implement Evidence-Based Medicine (EBM) effectively. This study endeavors to develop and validate a CIL questionnaire for medical residents of Isfahan University of Medical Sciences.

MATERIALS AND METHODS:
This study employs sequential-exploratory mixed methods in 2019. The participants were 200 medical residents in different specialties; they are selected through the convenience sampling method. In the first (qualitative) phase, an early CIL questionnaire was designed by reviewing literature and performing complementary interviews with health professionals. In the second (validation) phase, the questionnaire's face validity and content validity were confirmed. In the third (quantitative) phase, the construct validity was examined via Item-Response Theory (IRT) model, and the factor loading was computed. The gathered data were analyzed using descriptive statistics, t-test, two-way ANOVA, as well as two-parameter IRT model in R software.

RESULTS:
In the qualitative phase, the concept of CIL is initially described in seven main categories and 22 subcategories, and the items were formulated. An initial 125-item questionnaire was analyzed by the research team, leading to a 43-item. Through the content validity and face validity examination, we removed 11 and 4 items in the Content Validity Ratio (CVR) and Content Validity Index (CVI), respectively. Throughout the face validity analysis, none of the items were removed. According to the construct validity results, difficulty coefficient, discriminant coefficient, and factor loading were confirmed, most of the other questions achieved a proper factor loading value that is higher than 0.30, and a value of 0.66 was achieved for the reliability via the Kuder–Richardson method. Ultimately, the real-assessment 28-item CIL questionnaire was developed with four components.

CONCLUSIONS:
The CIL questionnaire could be employed to examine the actual CIL basic knowledge. Because of using the real-assessment approach rather than self-assessment in the design, it can be claimed that this instrument can provide a more accurate assessment of the information literacy status of medical residents. This valid questionnaire is used to measure and train the skills needed by healthcare professionals in the effective implementation of EBM.
Compensation based on work relative value unit for cardiovascular surgeons in Iran: A mixed method study
Authors: Forootan Sara , Danaei Saeed , Hajebrahimi Sakineh , Najafi Behzad , Asghari-Jafarabadi Mohammad , Janati Ali 
Published: October 2023

BACKGROUND:
Work relative value unit (wRVU) is a tool for assessing surgeons' performance, compensation, and productivity. It appears that wRVU for cardiovascular procedures does not consider complexity and its value for lengthy operations is low. The aim of the study is to determine wRVU for cardiovascular procedures in Iran according to the proposed approach.

MATTERIALS AND METHODS:
This study was conducted as a mixed method in teaching hospitals in Tabriz in the period of September 2020 to December 2021. According to Hospital Information System and expert opinions, six procedures in cardiovascular surgery were included in the study. They were compared with 18 procedures in neurosurgery, orthopedics, and otorhinolaryngology in terms of the operation time and wRVU/min. Then, we calculated new wRVUs for the selected procedures based on surgeons' opinions, time measurements, and anesthetists' points of view by content analysis in qualitative and statistical analysis in quantitative parts.

RESULTS:
Among the six cardiac procedures, the wRVU for five was under-estimated. The wRVU/min value ranged from 0/28 to 1/15 in the studied procedures. Findings demonstrate no significant relationship between the length of operations and the wRVU announced by the Ministry of Health and Medical Education (P value >0/05). Compared to studied procedures in four specialties, thoracoabdominal aortic aneurysm repair has the longest surgery time at 417 minutes. According to anesthesiologists, cardiovascular; orthopedics; ear, nose, and tongue; and neurosurgery specialties obtained 4/2, 2/9, 2/8, and 4, respectively, in terms of surgery duration, complexity, risk, and physical effort.

CONCLUSION:
Despite policymakers' attempts to bring justice to payments, it seems that there has been little progress in paying cardiovascular surgeons. Improper payment to cardiovascular surgeons will affect the future of the workforce in this specialty. Today, the need to reconsider the wRVUs in heart specialty is felt more than before.
Mindful self-care and mental well-being of university health educators and professionals in Hail Region, Saudi Arabia
Authors: Dando Lea L. , Velitario Anamarie M. , Mallillin Leovigildo Lito D. , Celdran Ma. Christina B. , Alcantara Jerold C. 
Published: October 2023

BACKGROUND:
Psychological stress is a familiar occurrence as it is linked with a sense of lack of control when up fronted with uncertainty. The study examines the mindful self-care practices of health educators and professionals in various domains and determines their relationship to the self-perceived level of mental well-being.

MATERIALS AND METHODS:
The study employs the quantitative descriptive approach. It was conducted in the Hail region in the academic year 2020–2021 and was participated by 91 respondents from various colleges. Self-care practices and mental well-being of health educators and professionals were determined using the Mindful Self-Care Scale and the Warwick Edinburgh Mental Well-being Scale. Pearson correlation (2-tailed) was performed to assess the significant relationship between self-care behavior and mental well-being. Post-hoc test for correlation was conducted between the mean rating for each variable for self-care behavior and the mean rating for mental well-being. This was tested at an appropriate probability value of 0.01 and 0.05.

RESULTS:
The overall mean for self-care behaviors of the respondents was 3.96 (SD 0.81) while the overall mental well-being score was 51.90 (SD 8.0). This was considered as average mental well-being, not indicative of possible/clinical depression. A significant relationship exists between the overall rating for self-care behavior and the overall rating for mental well-being (r = 0.661, P value < 0.001). Furthermore, with a correlation score of 0.661, the two variables have a moderately strong and significant positive relationship.

CONCLUSIONS:
The study affirmed the relationship between mindful self-care behaviors and mental well-being. Engaging in self-care practices regularly and frequently can develop one's well-being.
Sputnik V vaccine perception and hesitancy in a tertiary health care centre transformed to Covid-19 vaccine centre: A case study
Authors: Priyadharshini A , Begum Jarina , Ali Syed I. , Pattnaik Satyajit , Sharma Dhananjaya , Lalitha D Lakshmi 
Published: October 2023

BACKGROUND:
Sputnik V vaccine was approved in India in April 2021 to tackle the pandemic situation. However, there was lack of information on the effects, side effects, and peoples' perception toward it. The present case study aims to evaluate the vaccine coverage, the awareness, and perception toward it and compare the adverse effects after each dose.

MATERIALS AND METHODS:
A unique case study was conducted in a sample of 200 participants comparing 2 groups of population who took first and second dose of Sputnik V vaccine during June to November 2021. The data were collected by a prevalidated questionnaire, follow-up telephonic interviews focused on knowledge, awareness, side effects of vaccine, and analyzed using descriptive statistics such as frequency, percentages, mean, and standard deviation.

RESULTS:
The vaccine coverage for first and second doses were 98.3% and 96.5%, respectively. The mean age of the participant was 29 + 9.5 years and majority 68.5% were males. Seventeen percent experienced the S/E for the vaccine with 9.5% from second dose. There were usual side effects; however, it was more after second dose of vaccination. Friends and healthcare workers were the main source of information (33.5%) and motivation (43%). Majority (73.5%) were aware of the side effects. Forty three point five percent took vaccine attributed to its protective role, availability, and peer pressure. There was no significant association between type of doses and side effects of the respective doses of vaccine.

CONCLUSION:
The vaccine coverage was >90%. Participants were well aware of the vaccine and side effects which were more in second dose. However, there was no significant difference between the two doses of vaccine.
Comparison of the effectiveness of acceptance and commitment therapy (ACT) with metacognitive therapy (MCT) in objective cognitive information processing style of obsessive–compulsive patients (OCD)
Authors: Saeidi Lida , Afsharinia Karim , Kakabraee Keivan , Arefi Mokhtar 
Published: October 2023

BACKGROUND:
In recent studies, the deficit in the cognitive process has been investigated as one of the etiological hypotheses in a wide range of obsessive–compulsive disorders (OCD). This study aimed to compare the effectiveness of acceptance and commitment therapy (ACT) and metacognitive therapy (MCT) on objective cognitive information processing style in obsessive–compulsive patients.

MATERIALS AND METHODS:
This quasi-experimental study with a pre-test and post-test plan and a control group was conducted on 45 patients with OCD, matched with gender, age, and educational and marital status. The samples in three groups were selected using the convenience sampling method. Finally, the study participants were randomly divided into two experimental groups and one control group and assessed using Pacini and Epstein's rational experimental Inventory (REI) in two stages, pre-test, and post-test. The experimental groups received ACT and MCT weekly during eight and seven sessions and in a group.

RESULTS:
The results showed that ACT and MCT are effective at a significant level in the objective cognitive information processing style of obsessive–compulsive patients (P < 0.05). The post-test results showed that the effect of ACT in changing rational processing style is more effective than MCT treatment. Also, the effect of ACT on intuitive processing style changes was greater than on MCT treatment.

CONCLUSION:
The findings of this study indicate that ACT and MCT cause a significant change in intuitive style to rationalism in the thematic processing of cognitive information of obsessive–compulsive patients. According to the results, both methods of treatment improve the research variables in these patients.