bluuebunny/crossref_metadata_2025_split huggingface dataset:
Embedding optical fiber with laser metal deposition
Authors: Manns Martin , Raza Syed Muhammad , Morez Daniel , Schreiber Florian , Engel Bernd 
Published: January 2024

AbstractIn contrast to other additive manufacturing technologies, laser metal deposition (LMD) allows printing on existing metal parts. For smart tools, it would be advantageous to place fiber optics closely beneath surfaces in order to measure parameters, such as temperature and strains. This work presents a novel method to weld in fiber optical cables beneath sheet metal surfaces with LMD. Results show that the fiber optical cable can be enclosed in the metal, confirming the possibility of using LMD to embed fiber optical sensors in the metals. An applicable scan speed for welding has been identified. A need for a metallic strip on the surface of fiber has been identified, which prevents the fiber from being melted. Ceramic sleeve and multiple plastic layers around the cable successfully prevent the fiber from being destroyed. Further research on effects on the optical characteristics of the fibers is proposed.
Network analysis of monoamines involved in anxiety-like behavior in a rat model of osteoarthritis
Authors: Mlost Jakub , Białoń Magdalena , Kędziora Marta , Wąsik Agnieszka , Michalec Żaneta , Starowicz Katarzyna 
Published: January 2024

Abstract
Background
Chronic pain is a major health problem that affects a significant number of patients, resulting in personal suffering and substantial health care costs. One of the most commonly reported causal conditions is osteoarthritis (OA). In addition to sensory symptoms, chronic pain shares an inherent overlap with mood or anxiety disorders. The involvement of the frontal cortex, striatum and nucleus accumbens, in the affective processing of pain is still poorly understood.

Methods
Male Wistar rats were divided into two groups: MIA (monoiodoacetate injected into the knee—model of OA) and sham (NaCl). Behavioral tests assessing pain, anxiety, and depressive behavior were performed at week 1, 3, 4, 6, 8, and 10. Neurochemical assays were conducted at weeks 3, 6, and 10 post-MIA injection, followed by the neurotransmitters and their metabolites correlation matrix and network analysis.

Results
OA animals developed rapid pain phenotype, whereas anxiety-like behavior accompanied the development of a pain phenotype from 6 week post-MIA injection. We did not detect any depressive-like behavior. Instead, immobility time measured in the forced swimming test transiently decreased at 3 weeks post-MIA in the OA group. We detected changes in noradrenaline and serotonin levels in analyzed structures at distinct time points. Network analysis revealed noradrenaline and serotonin neurotransmission changes in the nucleus accumbens, confirming it to be the key structure affected by chronic pain.

Conclusion
Animals with chronic pain exhibit symptoms of anxiety-like behavior and we identified underlying neurochemical changes using network analysis.
Timing of Surgery for Proximal Humeral Fracture Treated with Shoulder Hemiarthroplasty, Best Results with Surgery Within 2 Weeks
Authors: Demir Yilmaz , Vuorinen Alma , Gordon Max , Nordqvist Anders , Salomonsson Björn 
Published: January 2024

Abstract
Background
Preoperative delay may affect the outcome of proximal humerus fractures treated with shoulder hemiarthroplasty. There is currently no consensus for the recommended preoperative time interval. The aim was to examine how the time to surgery with shoulder hemiarthroplasty after a proximal humerus fracture affected the patient-reported outcome.

Methods
380 patients with proximal humerus fractures treated with shoulder hemiarthroplasty recorded from the Swedish Shoulder Arthroplasty Registry were included. Three self-reporting outcome instruments were used at follow-up after 1–5 years: a shoulder-specific score, the Western Ontario Osteoarthritis of the Shoulder index (WOOS), the EuroQol-5 Dimension index (EQ-5D), and subjective patient satisfaction assessment.

Results
The preoperative delay had a negative impact on the WOOS, EQ-5D, and patient satisfaction level (p < 0.01). The best result, measured with WOOS at a minimum 1-year follow-up, was found when surgery was performed 6–10 days after the reported date of fracture. WOOS% 8–14 days was 69.4% (± 24.2). A delay of more than 10 days was shown to be correlated with poorer outcomes. WOOS% 15–60 days was 55.8% (± 25.0) and continued to decrease.

Conclusion
The current recommendation in Sweden to perform shoulder hemiarthroplasty within 2 weeks after sustaining a proximal humerus fracture is considered valid.
Assessment of seismic slope stability of Rangamati Hill Tracts, Bangladesh
Authors: Santo Saif Ahmed , Hossain A S M Fahad , Fariha Akhi Sultana , Haque Md. Ehsanul , Ansary Mehedi Ahmed 
Published: January 2024

AbstractSlope stability is an essential aspect of geotechnical engineering. Unstable slopes or stable slopes influenced by external factors may result in a catastrophic disaster called a landslide. In seismically active areas with steep terrain, landslides commonly occur and are regarded as one of the most severe threats. Bangladesh has not suffered any destructive earthquakes in recent years but has a considerable risk of facing such earthquakes owing to its geological conditions. Although slope failures occurring in the Rangamati Hill Tracts of Bangladesh are mainly rainfall-induced, due to the seismic risk in Bangladesh, it is essential to assess earthquake-induced slope failure in vulnerable areas. In this study, the authors analyzed the seismic slope stability at three locations in the Rangamati Hill Tracts using pseudostatic approaches. The pseudostatic approach with the variation in seismic force based on the seismic coefficient was utilized to determine the critical conditions. Using Newmark’s rigid block method, the permanent displacements for various slope conditions were calculated for the Kobe earthquake. The analysis provided crucial insight into the state of the locations. One location has a low factor of safety (FS) value at a slope angle of 30° or greater, whereas the others have a risk of slope failure at a slope angle of 50° or greater. Newmark’s displacement analysis also showed that the slopes at location 3 have the highest displacement at a lower slope angle, with location 1 and location 2 showing relatively better results than location 3. Structural and bioengineered preventive measures are needed in this area to reduce the vulnerability of possible slope failure.
Pilot implementation of a co-mentoring circles program for the clinical research professionals: Evidence for formative evaluation and logic model
Authors: Nelson July D. , Dunn Mendy E. , Levites Strekalova Yulia A. 
Published: January 2024

Abstract
Clinical research professionals (CRPs) are essential contributors to clinical and translational research endeavors, encompassing roles such as research nurses, research coordinators, data managers, and regulatory affairs specialists. This paper reports on the implementation of a novel training program for the CRPs, the Co-mentoring Circles Program, developed by the University of Florida Health Clinical Research Professionals Consortium, and proposes an initial logic model of CRP workforce development informed by the observations, participant feedback, and the established Translational Workforce Logic Model. The co-mentoring program was delivered through an online didactic curriculum and bi-monthly meetings over nine months, from January to September 2022. The formative evaluation identified the factors that support CRP workforce development through knowledge acquisition and professional relationship building. Finally, this paper proposes a logic model of CRP workforce development, including financial and human inputs, didactic and co-mentoring activities, workforce outputs, outputs related to workforce and clinical research study progress, and resulting impacts of increased national capacity for translational research and increased rate of research translation.
Expanding the Scope of Institutional Logics Research
Authors: Lounsbury Michael , Wang Milo Shaoqing 
Published: January 2024

AbstractThe institutional logics perspective provides a powerful theory that emphasizes how symbolic beliefs and material practices are intertwined in relatively enduring configurations that can profoundly shape behavior across space and time. In this article, we build upon the arguments and insights of Haveman, Joseph-Goteiner, and Li, suggesting the need for a broader research agenda on the dynamics of institutional logics in China and around the world. Building on some of our recent writings, we argue for the need to go beyond the study of how logics have effects, to understand how logics themselves cohere, endure, and co-evolve in dynamic interrelationships with other logics.
Bradykinin actions in the central nervous system: historical overview and psychiatric implications
Authors: Graeff Frederico Guilherme , Joca Sâmia , Zangrossi Helio 
Published: January 2024

AbstractBradykinin (BK), a well-studied mediator of physiological and pathological processes in the peripheral system, has garnered less attention regarding its function in the central nervous system, particularly in behavioural regulation. This review delves into the historical progression of research focused on the behavioural effects of BK and other drugs that act via similar mechanisms to provide new insights into the pathophysiology and pharmacotherapy of psychiatric disorders. Evidence from experiments with animal models indicates that BK modulates defensive reactions associated with panic symptoms and the response to acute stressors. The mechanisms are not entirely understood but point to complex interactions with other neurotransmitter systems, such as opioids, and intracellular signalling cascades. By addressing the existing research gaps in this field, we present new proposals for future research endeavours to foster a new era of investigation regarding BK’s role in emotional regulation. Implications for psychiatry, chiefly for panic and depressive disorders are also discussed.
Voltage-gated sodium channel gene mutation and P450 gene expression are associated with the resistance of Aphis spiraecola Patch (Hemiptera: Aphididae) to lambda-cyhalothrin
Authors: Tang Hong-cheng , Zhou Yu-rong , Zuo Jun-feng , Wang Yi-xuan , Piñero Jaime C. , Peng Xiong , Chen Mao-hua 
Published: January 2024

AbstractAphis spiraecola Patch is one of the most economically important tree fruit pests worldwide. The pyrethroid insecticide lambda-cyhalothrin is commonly used to control A. spiraecola. In this 2-year study, we quantified the resistance level of A. spiraecola to lambda-cyhalothrin in different regions of the Shaanxi province, China. The results showed that A. spiraecola had reached extremely high resistance levels with a 174-fold resistance ratio (RR) found in the Xunyi region. In addition, we compared the enzymatic activity and expression level of P450 genes among eight A. spiraecola populations. The P450 activity of A. spiraecola was significantly increased in five regions (Xunyi, Liquan, Fengxiang, Luochuan, and Xinping) compared to susceptible strain (SS). The expression levels of CYP6CY7, CYP6CY14, CYP6CY22, P4504C1-like, P4506a13, CYP4CZ1, CYP380C47, and CYP4CJ2 genes were significantly increased under lambda-cyhalothrin treatment and in the resistant field populations. A L1014F mutation in the sodium channel gene was found and the mutation rate was positively correlated with the LC50 of lambda-cyhalothrin. In conclusion, the levels of lambda-cyhalothrin resistance of A. spiraecola field populations were associated with P450s and L1014F mutations. Our combined findings provide evidence on the resistance mechanism of A. spiraecola to lambda-cyhalothrin and give a theoretical basis for rational and effective control of this pest species.
Exploring trauma exposure and post-traumatic stress in university students of different identity statuses in Lithuania and Japan
Authors: Truskauskaite Inga , Sugimura Kazumi , Abe Kazuaki , Hihara Shogo , Haramaki Yutaka , Jovarauskaite Lina , Kamite Yuka , Kazlauskas Evaldas 
Published: January 2024

AbstractEmerging adulthood is the time when identity questions are addressed. It is also a time of excessive stress and risk for mental health problems. Different identity statuses relate to different mental health outcomes. Yet, little research has addressed how identity status is interlinked with trauma exposure and post-traumatic stress reactions, especially in multicultural contexts. The current study aimed to explore whether different traumatic experiences are related to the current identity status of university students aged between 18 and 29 years and investigate to what extent trauma-exposed emerging adults of different identity statuses report symptoms of post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD). In total, 2237 university students from Lithuania (n = 791) and Japan (n = 1345) participated in the current study. Identity profiles were revealed by using the Latent Class Analysis approach. Lithuania and Japan were comparable in terms of identity profiles and structure of PTSD/CPTSD. Trauma-exposed emerging adults reported a higher probability of being in troubled diffusion identity status; students in achievement identity status had a lower probability of CPTSD and lower rates of symptoms of disturbances in self-organization. The diffused identity of emerging adults from Lithuania and Japan is associated with trauma exposure, and positive identity is linked with fewer CPTSD reactions.
Reassessing the need for carbon dioxide removal: moral implications of alternative climate target pathways
Authors: Voget-Kleschin Lieske , Baatz Christian , Heyward Clare , Van Vuuren Detlef , Mengis Nadine 
Published: January 2024

Abstract

Non-technical summary
Scenarios compatible with the Paris agreement's temperature goal of 1.5 °C involve carbon dioxide removal measures – measures that actively remove CO2 from the atmosphere – on a massive scale. Such large-scale implementations raise significant ethical problems. Van Vuuren et al. (2018), as well as the current IPCC scenarios, show that reduction in energy and or food demand could reduce the need for such activities. There is some reluctance to discuss such societal changes. However, we argue that policy measures enabling societal changes are not necessarily ethically problematic. Therefore, they should be discussed alongside techno-optimistic approaches in any kind of discussions about how to respond to climate change.

Technical summary
The 1.5 °C goal has given impetus to carbon dioxide removal (CDR) measures, such as bioenergy combined with carbon capture and storage, or afforestation. However, land-based CDR options compete with food production and biodiversity protection. Van Vuuren et al. (2018) looked at alternative pathways including lifestyle changes, low-population projections, or non-CO2 greenhouse gas mitigation, to reach the 1.5 °C temperature objective. Underlined by the recently published IPCC AR6 WGIII report, they show that demand-side management measures are likely to reduce the need for CDR. Yet, policy measures entailed in these scenarios could be associated with ethical problems themselves. In this paper, we therefore investigate ethical implications of four alternative pathways as proposed by Van Vuuren et al. (2018). We find that emission reduction options such as lifestyle changes and reducing population, which are typically perceived as ethically problematic, might be less so on further inspection. In contrast, options associated with less societal transformation and more techno-optimistic approaches turn out to be in need of further scrutiny. The vast majority of emission reduction options considered are not intrinsically ethically problematic; rather everything rests on the precise implementation. Explicitly addressing ethical considerations when developing, advancing, and using integrated assessment scenarios could reignite debates about previously overlooked topics and thereby support necessary societal discourse.

Social media summary
Policy measures enabling societal changes are not necessarily as ethically problematic as commonly presumed and reduce the need for large-scale CDR.
Spatial Patterns of Vegetation Activity Related to ENSO in Northern South America
Authors: Estupinan‐Suarez Lina M. , Mahecha Miguel D. , Brenning Alexander , Kraemer Guido , Poveda Germán , Reichstein Markus , Sierra Carlos A. 
Published: January 2024

AbstractInterannual variability of vegetation activity (i.e., photosynthesis) is strongly correlated with El Niño Southern Oscillation (ENSO). Globally, a reduction in carbon uptake by terrestrial ecosystems has been observed during the ENSO warm phase (El Niño) and the opposite during the cold phase (La Niña). However, this global perspective obscures the heterogeneous impacts of ENSO at regional scales. Particularly, ENSO has contrasting impacts on climate in northern South America (NSA) depending on the ENSO phase and geographical location, which in turn affect the activity of vegetation. Furthermore, changes of vegetation activity during multiple ENSO events are not well understood yet. In this study, we investigated the spatial and temporal differences in vegetation activity associated with ENSO variability and its three phases (El Niño, La Niña, Neutral) to identify hotspots of ENSO impacts in NSA, a region dominated by rainforest and savannas. To achieve this, we investigated time series of vegetation variables from 2001 to 2014 at moderate spatial resolution (0.0083°). Data were aggregated through dimensionality reduction analysis (i.e., Global Principal Component Analysis). The leading principal component served as a proxy of vegetation activity (VAC). We calculated the cross‐correlation between VAC and the multivariate ENSO index separately for each ENSO phase. Our results show that El Niño phase has a stronger impact on vegetation activity both in intensity and duration than La Niña phase. Moreover, seasonally dry ecoregions were more susceptible to El Niño impacts on vegetation activity. Understanding these differences is key for regional adaptation and differentiated management of ecosystems.
Helicity: A Possible Indicator of Negative Feedback Initiation of Tropical Cyclone–Ocean Interaction
Authors: Munsi A. , Kesarkar A. P. , Bhate J. N. , Tallapragada V. S. 
Published: January 2024

AbstractThe development of large‐scale vortex dynamo during tropical cyclogenesis through the mutual intensification of primary and secondary circulation in terms of helical evolution is well studied. However, the influence of atmospheric helicity on ocean surface heat and moisture fluxes associated with tropical cyclone (TC) evolution is yet to be understood. At its development stage, the heat and moisture flux from the ocean surface increases with the increase in intensity of the TC. This time, TC‐Ocean interaction works in a positive feedback mechanism. However, after a particular stage, the very intense wind of the TC causes strong turbulent mixing in the underlying ocean. Hence, the upper ocean layer temperature starts decreasing, leading to a decrease in heat and moisture flux exchange to the TC. We have analyzed the emergence of vortex helical structure in TC and the role of helicity in modulating surface heat and moisture fluxes. The result shows that helical development is associated with the axisymetrization of the vertical velocity and diabatic heating at the middle and upper troposphere. There is no definite TC intensity at which the initiation of negative feedback of TC‐upper ocean interaction occurs. However, the increase in helicity above 200 × 10−2 ms−2 reversed the TC‐ocean interaction trend. Therefore, TC helicity evolution and upper ocean interaction are essential to understand TC evolution.
Impact of Uncertainties in Land Surface Processes on Subseasonal Predictability of Heat Waves Onset Over the Yangtze River Valley
Authors: Zhang Qiyu , Sun Guodong , Dai Guokun , Mu Mu 
Published: January 2024

AbstractLand surface processes are strongly associated with heat waves (HWs). However, how the uncertainties in land surface processes owing to inaccurate physical parameters influence subseasonal HW predictions has rarely been explored. To examine the impact of parameter errors of land surface processes on the uncertainty of subseasonal HW predictions, five strong and long‐lasting HW events over the middle and lower reaches of the Yangtze River are investigated. Based on the Weather Research and Forecasting model, the conditional nonlinear optimal perturbation related to parameters (CNOP‐P) approach is employed to address the aforementioned issues. Numerical results demonstrate that the CNOP‐P type errors of physical parameters cause large prediction errors for five HW event onsets. Two types of CNOP‐Ps are obtained for HW events, called the type‐1 CNOP‐P and the type‐2 CNOP‐P. The type‐1 (type‐2) CNOP‐P causes an approximately 3°C (2°C) warm (cold) bias during the HW period. Surface sensible and latent heat flux errors, especially flux exchange between vegetation canopy and canopy air, provide considerable uncertainty in subseasonal HW predictions. The type‐1 (type‐2) CNOP‐P exhibits an underestimation (overestimation) of transpiration. Furthermore, it should be noted that the type‐1 CNOP‐P results in a substantial difference in soil moisture, a phenomenon that is demonstrated to be challenging to observe in the type‐2 CNOP‐P. The results indicate that understanding vegetation‐atmosphere dynamics is crucial for improving subseasonal HW predictions. Jointly lowering soil‒atmosphere and vegetation‐atmosphere uncertainty can notably improve subseasonal HW prediction skills.
Future Change in Urban Flooding Using New Convection‐Permitting Climate Projections
Authors: Archer L. , Hatchard S. , Devitt L. , Neal J. C. , Coxon G. , Bates P. D. , Kendon E. J. , Savage J. 
Published: January 2024

AbstractRainfall intensity in the United Kingdom is projected to increase under climate change with significant implications for rainfall‐driven (combined pluvial and fluvial) flooding. In the UK, the current recommended best practice for estimating changes in pluvial flood hazard under climate change involves applying a simple percentage uplift to spatially uniform catchment rainfall, despite the known importance of the spatial and temporal characteristics of rainfall in the generation of pluvial floods. The UKCP Local Convective Permitting Model (CPM) has for the first time provided the capacity to assess changes in flood hazard using hourly, 2.2 km CPM precipitation data that varies in space and time. Here, we use an event set of ∼13,500 precipitation events across the three UKCP Local epochs (1981–2000, 2021–2040, and 2061–2080) to simulate rainfall‐driven flooding using the LISFLOOD‐FP hydrodynamic model at 20 m resolution over a 750 km2 area of Bristol and Bath, UK. We find that both the event set and uplift approaches indicate an increase in flood hazard under near‐term (2021–2040) and future (2061–2080) climate change. However, the event set produces markedly higher estimates of flood hazard when compared to the uplift approach, ranging from 19% to 49% higher depending on the return period. This suggests including the full spatiotemporal rainfall variability and its future change in rainfall‐driven flood modeling is critical for future flood risk assessment.