bluuebunny/crossref_metadata_2025_split huggingface dataset:
CO2‐Assisted Induced Self‐Assembled Aramid Nanofiber Aerogel Composite Solid Polymer Electrolyte for All‐Solid‐State Lithium‐Metal Batteries
Authors: Da Xinyu , Chen Jing , Qin Yanyang , Zhao Jianyun , Jia Xin , Zhao Yuanjun , Deng Xuetian , Li Yanan , Gao Na , Su Yaqiong , Rong Qiang , Kong Xiangpeng , Xiong Junqiao , Hu Xiaofei , Ding Shujiang , Gao Guoxin 
Published: January 2024

AbstractAll‐solid‐state lithium metal batteries (ASSLMBs) hold great promise for the development of next‐generation high‐safety, high‐energy‐density lithium batteries, but still face the challenges of lithium dendrite growth and thickness. Herein, the ultrathin PEO‐based composite solid polymer electrolyte (denoted as PAL) supported by a low‐density self‐supporting aramid nanofiber (ANF) aerogel framework is developed. The ANF aerogel obtained by a novel CO2‐assisted induced self‐assembly method has a well‐designed bilayer structure with double cross‐linking degree. Benefiting from the intermolecular interaction between ANFs and PEO, the PAL achieves an ultrathin thickness (20 µm) with excellent thermal stability and mechanical strength. Meanwhile, due to the modulation of ionic pathways by the functionalized ANF, the PAL achieves uniform lithium deposition without dendrites, resulting in stable long cycling (1400 h) for symmetric cells. Consequently, the Li|PAL|LiFePO4 (LFP) cell has excellent long‐term cycling stability (1 C, >700 cycles, Coulombic efficiency > 99.8%) and fast charge/discharge performance (rate, 10 C). More practically, the Li|PAL|LFP cell achieves an energy density of 180 Wh kg−1 due to the ability to match a high‐loading (8 mg cm−2) cathode. Furthermore, the double‐layer Li|PAL|LFP pouch cell demonstrates excellent flexibility and safety in cycling and abuse tests.
Addressing Triboelectric Nanogenerator Impedance for Efficient CO2 Utilization
Authors: Kim Do‐Heon , Kim Jin‐Kyeom , Choi Sung Yeol , Yang Ya , Song Hyun‐Cheol , Park Hye Sung , Shim Minseob , Baik Jeong Min 
Published: January 2024

AbstractReducing the impedance of a triboelectric nanogenerator (TENG) without power loss is crucial for enhancing its energy conversion efficiency and overall performance. In this paper, a novel signal management structure, based on a newly designed sliding‐mode TENG, aimed at effectively reducing impedance by converting narrow, instantaneous signals into broader ones is presented. This transformation is accomplished by adding a grounded electrode connected to a high‐inductive inductor and fine‐tuning the parasitic capacitance of the dielectric material. Utilizing a highly resistive material like P(VDF–TrFE), a significant improvement in the TENG's performance is achieved, resulting in an increase of output power to 0.352 mW and a decrease in impedance from 3.2 to 0.3 MΩ. This results in a threefold increase in charging speed, which can be attributed to the reduced charge loss and improved matching at lower impedance. Based on these promising findings, the enhanced TENG is successfully connected to power a system for electrochemical CO2 reduction for CO production. This system effectively reduces the required electrochemical reduction potential by ≈15% under real environments.
Urea ammonium nitrate placement methods, row patterns, and irrigation effects on corn productivity in a humid subtropical region
Authors: Vargas Amilcar , Singh Gurbir , Kaur Gurpreet , Lo Tsz Him , Spencer G. D. , Krutz L. Jason , Gholson Drew M. 
Published: January 2024

AbstractCrop yields are adversely affected by nitrogen (N) losses in humid subtropical regions. This study was conducted to determine whether N dynamics could be manipulated through planting geometry and fertilizer placement. The effects of irrigation (irrigated and rainfed), row pattern (single‐ and twin‐row), and N placement (surface dribble, one knife, two knives, and control) on corn (Zea mays L.) productivity and N use efficiency were investigated at Leland, Mississippi, on a Bosket very fine sandy loam. The total N rate was split into two equal halves of 128 kg N ha−1 at V2 and V6 growth stages. The effects of row pattern and N placement were consistent between irrigated and rainfed environments. There was no interaction between row pattern and N placement nor did row pattern affect corn productivity or N use efficiency parameters. In 2020, when less than 30 mm of rainfall occurred from the first N application through 2 weeks after the last N application, corn grain yield and agronomic N efficiency were not different among placement methods and averaged 11.1 Mg ha−1 and 20.3 kg grain kg−1 fertilizer N, respectively. However, in 2021, applying N with one knife increased corn grain yield by 7% to 14% compared to the two knives and surface dribble application methods; in that year, 235 mm of rainfall occurred from the first N application through 2 weeks after the last N application. Applying N with one knife appears to consistently improve crop productivity and N use efficiency parameters for both irrigated and rainfed environments.
Vermicompost and bactericide application minimized common bacterial blight development and enhanced nodulation and agronomic performances of bean varieties in Southern Ethiopia
Authors: Terefe Habtamu , Mengesha Getachew G. , Abera Asinake , Kebede Erana , Yitayih Getnet 
Published: January 2024

AbstractCommon bacterial blight (CBB) is an economically important disease that results in quantitative and qualitative yield reductions across the world. Field experiments were conducted to evaluate the effectiveness of the integration of host resistance, vermicompost (VC) seed soaking, and bactericide foliar application against CBB development, nodulation, and agronomic performances of common bean varieties in southern Ethiopia in 2021 and 2022. Two bean varieties (Remeda [moderately resistant] and Awash‐01 [susceptible]), VC (soaking and non‐soaking), and bactericide spraying (unsprayed, 7‐, 14‐, and 21‐day intervals) were regarded as treatments and factorially arranged in a randomized complete block design with three replications. The combined analysis of variance over years revealed significant (p < 0.05) variations in disease severity, area under disease progress curve (AUDPC), nodule, and agronomic parameters between varieties, VC, bactericide spray intervals, and the interaction of the three factors. Seed soaking with VC and three times foliar bactericide application at the 7‐day interval recorded the lowest terminal disease severity (21.30%) and AUDPC (791.67%‐days) and the highest grain yield (4128.80 kg ha−1), nodule, and other agronomic traits for the variety Remeda over the other treatments. Moreover, the same treatment also obtained the highest net benefit of $2729.88 ha−1 and marginal rate of return of 15.94 over untreated plots of the variety Remeda. Similar trends were observed for the variety Awash‐01. Therefore, the findings indicate that the integration of VC seed soaking, thrice application of bactericide at the 7‐day interval along with the variety Remeda can be employed to curtail the effects of CBB and optimize nodulation and agronomic performances of the crop and is recommended for growers in the study areas.
Above‐Tg Annealing Benefits in Nanoparticle‐Stabilized Carbon Molecular Sieve Membrane Pyrolysis for Improved Gas Separation
Authors: Cao Yuhe , Liu Zhongyun , Koros William J. 
Published: January 2024

AbstractNanoparticles can suppress asymmetric precursor support collapse during pyrolysis to create carbon molecular sieve (CMS) membranes. This advance allows elimination of standard sol‐gel support stabilization steps. Here we report a simple but surprisingly important thermal soaking step at 400 °C in the pyrolysis process to obtain high performance CMS membranes. The composite CMS membranes show CO2/CH4 (50 : 50) mixed gas feed with an attractive CO2/CH4 selectivity of 134.2 and CO2 permeance of 71 GPU at 35 °C. Furthermore, a H2/CH4 selectivity of 663 with H2 permeance of 240 GPU was achieved for promising green energy resource‐H2 separation processes.
Multimodal Engineering of Catalytic Interfaces Confers Multi‐Site Metal‐Organic Framework for Internal Preconcentration and Accelerating Redox Kinetics in Lithium‐Sulfur Batteries
Authors: Lu Haibin , Zeng Qinghan , Xu Liangliang , Xiao Yingbo , Xie Lin , Yang Junhua , Rong Jionghui , Weng Jingqia , Zheng Cheng , Zhang Qi , Huang Shaoming 
Published: January 2024

AbstractThe development of highly efficient catalysts to address the shuttle effect and sluggish redox kinetics of lithium polysulfides (LiPSs) in lithium‐sulfur batteries (LSBs) remains a formidable challenge. In this study, a series of multi‐site catalytic metal‐organic frameworks (MSC‐MOFs) were elaborated through multimodal molecular engineering to regulate both the reactant diffusion and catalysis processes. MSC‐MOFs were crafted with nanocages featuring collaborative specific adsorption/catalytic interfaces formed by exposed mixed‐valence metal sites and surrounding adsorption sites. This design facilitates internal preconcentration, a coadsorption mechanism, and continuous efficient catalytic conversion toward polysulfides concurrently. Leveraging these attributes, LSBs with an MSC‐MOF‐Ti catalytic interlayer demonstrated a 62 % improvement in discharge capacity and cycling stability. This resulted in achieving a high areal capacity (11.57 mAh cm−2) at a high sulfur loading (9.32 mg cm−2) under lean electrolyte conditions, along with a pouch cell exhibiting an ultra‐high gravimetric energy density of 350.8 Wh kg−1. Lastly, this work introduces a universal strategy for the development of a new class of efficient catalytic MOFs, promoting SRR and suppressing the shuttle effect at the molecular level. The findings shed light on the design of advanced porous catalytic materials for application in high‐energy LSBs.
Organocatalytic Enantioselective Synthesis of Seven‐Membered Ring with Inherent Chirality
Authors: Li Jia‐Hao , Li Xiao‐Kai , Feng Jia , Yao Wang , Zhang Huan , Lu Chuan‐Jun , Liu Ren‐Rong 
Published: January 2024

AbstractInherent chirality is used to describe chiral cyclic molecules devoid of central, axial, planar, or helical chirality and has tremendous applications in chiral recognition and enantioselective synthesis. Catalytic and divergent syntheses of inherently chiral molecules have attracted increasing interest from chemists. Herein, we report the enantioselective synthesis of inherently chiral tribenzocycloheptene derivatives via chiral phosphoric acid (CPA)‐catalyzed condensation of cyclic ketones and hydroxylamines. This chemistry paves the way to accessing the less stable derivatives of 7‐membered rings with inherent chirality. A series of chiral tribenzocycloheptene oxime ethers was synthesized in good yields (up to 97 %) with excellent enantioselectivities (up to 99 % ee).
Precisely Manipulating Molecular Packing via Tuning Alkyl Side‐Chain Topology Enabling High‐Performance Nonfused‐Ring Electron Acceptors
Authors: Han Ziyang , Zhang Cai'e , He Tengfei , Gao Jinhua , Hou Yuqi , Gu Xiaobin , Lv Jikai , Yu Na , Qiao Jiawei , Wang Sixuan , Li Congqi , Zhang Jianqi , Wei Zhixiang , Peng Qian , Tang Zheng , Hao Xiaotao , Long Guankui , Cai Yunhao , Zhang Xin , Huang Hui 
Published: January 2024

AbstractIn the development of high‐performance organic solar cells (OSCs), the self‐organization of organic semiconductors plays a crucial role. This study focuses on the precisely manipulation of molecular assemble via tuning alkyl side‐chain topology in a series of low‐cost nonfused‐ring electron acceptors (NFREAs). Among the three NFREAs investigated, DPA‐4, which possesses an asymmetric alkyl side‐chain length, exhibits a tight packing in the crystal and high crystallinity in the film, contributing to improved electron mobility and favorable film morphology for DPA‐4. As a result, the OSC device based on DPA‐4 achieves an excellent power conversion efficiency of 16.67 %, ranking among the highest efficiencies for NFREA‐based OSCs.
Photo‐self‐Fenton Reaction Mediated by Atomically Dispersed Ag−Co Photocatalysts toward Efficient Degradation of Organic Pollutants
Authors: Lian Zichao , Gao Fangfang , Xiao Han , Luo Di , Li Mengyuan , Fang Duoduo , Yang Yupeng , Zi Jiangzhi , Li Hexing 
Published: January 2024

AbstractAchieving the complete mineralization of persistent pollutants in wastewater is still a big challenge. Here, we propose an efficient photo‐self‐Fenton reaction for the degradation of different pollutants using the high‐density (Ag: 22 wt %) of atomically dispersed AgCo dual sites embedded in graphic carbon nitride (AgCo−CN). Comprehensive experimental measurements and density functional theory (DFT) calculations demonstrate that the Ag and Co dual sites in AgCo−CN play a critical role in accelerating the photoinduced charge separation and forming the self‐Fenton redox centers, respectively. The bimetallic AgCo−CN exhibited excellent photocatalytic performance toward the phenol even under extreme conditions due to an efficient degradation pathway and in situ generation of the hydrogen peroxide producing the main active oxygen species (⋅OH and 1O2) and showed long‐term activity in a self‐design photo‐Filter reactor for the purification of the phenol. Our discoveries pave the way for the design of efficient single‐atoms photocatalysts‐based photo‐self‐Fenton reaction for recalcitrant pollutant treatment.
Thoracic delirium index for predicting postoperative delirium in elderly patients following thoracic surgery: A retrospective case‐control study
Authors: Li Jianli , Liu Jing , Zhang Mingming , Wang Jing , Liu Meinv , Yu Dongdong , Rong Junfang 
Published: January 2024

AbstractBackgroundPostoperative delirium (POD) is an acute neurological complication in the elderly undergoing thoracic surgery and can result in serious adverse consequences.AimsThis study aimed to identify the related risk factors for POD following thoracic surgery, primarily focusing on preoperative serum biomarkers, and further to establish a novel delirium index to better predict POD.MethodsA total of 279 patients aged ≥60 years who underwent elective thoracic surgery from August 2021 to August 2022 were enrolled in this observational study. The platelet‐to‐white blood cell ratio (PWR) was calculated as number the of platelets divided by the number of white blood cells. POD was defined by the confusion assessment method twice daily during the postoperative first 3 days. Multivariate regression analysis was performed to identify all potential variables for POD. Moreover, a novel thoracic delirium index (TDI) was developed based on the related risk factors. The accuracy of TDI and its component factors in predicting POD was determined by the curve of receiver operating characteristic (ROC).ResultsIn total, 25 of 279 patients developed POD (8.96%). Age, PWR, and average pain scores within the first 3 days after surgery were regarded as the independent risk factors for POD. Moreover, the ROC analysis showed the TDI, including age, PWR, and average pain scores within the first 3 days after surgery, can more accurately predict POD with the largest area under the curve of 0.790 and the optimal cutoff value of 9.072, respectively.ConclusionThe TDI can scientifically and effectively predict POD to provide optimal clinical guidance for older patients after thoracic surgery.
Effect of electroacupuncture on global cerebral ischemia‑reperfusion injury in rats: A urine proteome analysis
Authors: Zhang Xiao , Dai Yuting , Ma Fuguo , Ma Yuan , Wang Jiajia , Li Xiaoxia , Qin Weiwei 
Published: January 2024

AbstractBackgroundThis study aimed to investigate dynamic urinary proteome changes of electroacupuncture (EP) on cerebral ischemia‑reperfusion (CI/R) injured rats and to explore the therapeutic biological mechanisms of EP.MethodsFirst, changed urinary proteins were found in EP stimulation in healthy rats. Then, we used a CI/R injury rat model induced by Pulsinelli's four‐vessel occlusion (4‐VO) method to explore the function of EP on urinary proteome in CI/R injury. Urine samples were collected for proteome analysis by liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) and bioinformatics analysis.ResultsIn total, 384 proteins were identified, among which 47 proteins (23 upregulated, 24 downregulated) were differentially expressed with 0.6‐log FC and p < .05. Gene ontology analysis revealed that the cell redox homeostasis, acute‐phase response, response to lipopolysaccharide, and cellular response to glucocorticoid stimulus were significantly enriched. The partially biologically connected differential proteins were found by the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis in the EP group. With the CI/R rat model, 80 proteins (27 upregulated, 53 downregulated) were significantly changed in the CI/R rats compared to the controls. Among these differentially expressed proteins (DEPs), 23 proteins (17 upregulated, six downregulated) showed significant changes after EP treatment (0.6‐log FC change, p < .05). The main related biological processes were aging, immune response, acute‐phase response, liver regeneration, protein catabolic process, and response to oxidative stress. Many metabolic pathways were enriched by KEGG analysis.ConclusionOur results indicate that the EP could alleviate cerebral damage induced by ischemia‑reperfusion through an anti‐inflammatory and metabolism regulation mechanism. The urinary proteome might reflect the pathophysiological changes in EP pretreatment in the treatment and prevention of CI/R injury.
The accuracy and reliability of different midsagittal planes in the symmetry assessment using cone‐beam computed tomography
Authors: Yu Shaoyang , Zheng Yao , Dong Lirong , Huang Wenli , Wu Haoting , Zhang Qiang , Yan Xiao , Wu Wei , Lv Tao , Yuan Xiao 
Published: January 2024

AbstractSymmetry is an essential component of esthetic assessment. Accurate assessment of facial symmetry is critical to the treatment plan of orthognathic surgery and orthodontic treatment. However, there is no internationally accepted midsagittal plane (MSP) for orthodontists and orthognathic surgeons. The purpose of this study was to explore a clinically friendly MSP, which is more accurate and reliable than what is commonly used in symmetry assessment. Forty patients with symmetric craniofacial structures were analyzed on cone‐beam computed tomography (CBCT) scans. The CBCT data were exported to the Simplant Pro software to build four reference planes that were constructed by nasion (N), basion (Ba), sella (S), odontoid (Dent), or incisive foramen (IF). A total of 31 landmarks were located to determine which reference plane is the most optimal MSP by comparing the asymmetry index (AI). The mean value of AI showed a significant difference (p < 0.05) among four reference planes. Also, the mean value of AI for all landmarks showed that Plane 2 (consisting of N, Ba, and IF) and Plane 4 (consisting of N, IF, and Dent) were more accurate and stable. In conclusion, the MSP consisting of N, Dent, and IF shows more accuracy and reliability than the other planes. Further, it is more clinically friendly because of its significant advantage in landmarking.
Rhodanine Derivatives Containing 5‐Aryloxypyrazole Moiety as Anti‐inflammatory and Anticancer Agents
Authors: Zhu Lin , Ye Chao , Chen Shuang , Fang Yuqi , Zhang Yu , Zhang Tianyi 
Published: January 2024

AbstractIn this study, a series of rhodanine derivatives containing 5‐aryloxypyrazole moiety were identified as potential agents with anti‐inflammatory and anticancer properties. Most of the synthesized compounds demonstrated anti‐inflammatory and anticancer activity. Notably, compound 7 g (94.1 %) exhibited significant anti‐inflammatory activity compared with the reference drugs celecoxib (52.5 %) and hydrocortisone (79.4 %). Compound 7 g, at various concentrations, effectively inhibited nitric oxide (NO) production in a dose‐dependent manner. Western blot results showed that compound 7 g could prevents LPS‐induced expression of inflammatory mediators in macrophages. Enzyme‐linked immunosorbent assay (ELISA) assay suggested that 7 g is a promising compound capable of blocking the downstream signaling of COX‐2. In summary, these findings indicate that compound 7 g could be a promising candidate for further investigation.
Comparing the rate of immunotherapy treatment change due to toxicity by sex
Authors: Chua Kevin J. , Kronstedt Shane , Kaldany Alain , Srivastava Arnav , Doppalapudi Sai Krishnaraya , Liu Hao , Tarhini Ahmad A. , Gatti‐Mays Margaret , Gaughan Elizabeth , Hu‐Lieskovan Siwen , Aljumaily Raid , Nepple Kenneth , Schneider Bryan , Sterling Joshua , Singer Eric A. 
Published: January 2024

AbstractBackgroundImmuno‐oncology therapy (IO) is associated with a variety of treatment‐related toxicities. However, the impact of toxicity on the treatment discontinuation rate between males and females is unknown. We hypothesized that immune‐related adverse events would lead to more frequent treatment changes in females since autoimmune diseases occur more frequently in females.AimsOur aim was to determine if there was a difference in the rate of immunotherapy treatment change due to toxicity between males and females.Methods and ResultsThe Oncology Research Information Exchange Network Avatar Database collected clinical data from 10 United States cancer centers. Of 1035 patients receiving IO, 447 were analyzed, excluding those who did not have documentation noting if a patient changed treatment (n = 573). Fifteen patients with unknown or gender‐specific cancer were excluded. All cancer types and stages were included. The primary endpoint was documented treatment change due to toxicity. Four hundred and forty‐seven patients (281 males and 166 females) received IO treatment. The most common cancers treated were kidney, skin, and lung for 99, 84, and 54 patients, respectively. Females had a shorter IO course than males (median 3.7 vs. 5.1 months, respectively, p = .02). Fifty‐four patients changed treatment due to toxicity. There was no significant difference between females and males on chi‐square test (11.4% vs. 12.5%, respectively, p = 0.75) and multivariable logistic regression (OR 0.924, 95% CI 0.453–1.885, p = .827). Significantly more patients with chronic obstructive pulmonary disease (COPD) changed therapy due to toxicity (OR 2.491, 95% CI 1.025–6.054, p = .044).ConclusionFemales received a shorter course of IO than males. However, there was no significant difference in the treatment discontinuation rate due to toxicity between males and females receiving IO. Toxicity‐related treatment change was associated with COPD.
Bioequivalence and Safety Assessment of 2 Formulations of Low‐Dose Metformin Hydrochloride under Fasting Conditions in Healthy Chinese Participants: A Randomized Phase 1 Clinical Trial
Authors: Sun Ming‐Li , Xu Xin‐Wen , Liu Chen , Tong Yuan‐Xu , Wei Ya‐Li , Liu Hui‐Juan , Zhang Wei , Wang Xing‐He 
Published: January 2024

AbstractThe incidence of type 2 diabetes is high, and the existing metformin hydrochloride (MH) tablets of 250 mg cannot meet the demands of the Chinese drug market. This study aimed to evaluate the bioequivalence and safety of generic formulations of MH tablets (test formulation [T], 250 mg/tablet) and innovative products (reference formulation [R], 250 mg/tablet) under fasting conditions. This was an open‐label, single‐dose, 2‐period, 2‐sequence crossover, single‐center, randomized phase I clinical trial. T and R were considered bioequivalent if the adjusted geometric mean ratios (GMRs) and 90% confidence intervals of the area under the curve (AUC) and maximum concentration (Cmax) were within the range of 0.8‐1.25. Thirty‐five participants completed the trial. The T/R adjusted GMRs (95.7% for Cmax, 98.7% for AUC0→t, 98.8% for AUC0→∞) were within the acceptable bioequivalence range of 80%‐125%. No serious adverse events or suspected or unexpected serious adverse reactions occurred during this trial. The study findings confirmed that generic MH is a well‐tolerated and bioequivalent alternative to innovative products under fasting conditions in healthy Chinese participants. (www.chinadrugtrials.org.cn; registration no. CTR20190356)