bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pituitary‐ovarian hormones after low‐dose endometrial afterloading irradiation
Authors: Grönroos M. , Kauppila O. , Pulkkinen M. , Turunen S. , Salmi T. , Raekallio J. 
Published: April 2004

AbstractLow‐dose endometrial after loading irradiation was used in 19 mentally retarded women for the induction of therapeutic amenorrhea. They were divided into two subgroups on the basis of age: 13 young patients (mean age 17 years, range 13–26 years) and six patients of middle age (mean age 42 years, range 34–44 years).In the young patients, during the 10‐month month follow‐up period, the plasma E2 levels did not decrease. HOwever, the FSH concentration increased. Later on, 2–9 years after treatment, the E2 levels were significantly higher than those of healthy postmenopausal women and did not differ from the values of healthy women in the sixth to seventh days of the menstrual cycle. At that time the FSH and LH levels were similar to reference values in reproductive age. The E2/E1 ratio was significantly higher than that of healthy women in the sixth to seventh days of the cycle and that of postmenopausal women. Most of the menstrual cycles were anovulatory but some ovulatory also occurred. The testosterone concentrations did not differ from reference values. The ovaries of the middle age patients were more sensitive to irradiation than those of the younger patients.
Placental protein 5 (PP5) in severe pre‐eclampsia and eclampsia
Authors: Lee J.N. , Salem H.T. , Huang S.C. , Ouyang P.C. , Seppälä M. , Chard T. 
Published: April 2004

AbstractCirculating levels of placental protein 5 (PP5) were studied in patients with severe pre‐eclampsia and eclampsia. Elevated PP5 levels were frequently observed in the eclampsia group. This elevation may be due to disturbance in endogenous coagulation mechanisms at the placental site.
Circulating blood levels of gonadotropins and prolactin in the normal menstrual cycle
Authors: Dada O.A. , Ladipo O.A. , Osotimehin B.O. , Nduka E.U. 
Published: April 2004

AbstractCirculating blood levels of luteinizing hormone, follicle‐stimulating hormone and prolactin are reported in 17 normally menstruating Nigerian women. The profiles of the secretion of these pituitary hormones are similar to those reported in other ethnic groups. A significant midcycle peak of prolactin, coinciding with the peaks of luteinizing hormone and follicle stimulating hormone was also observed.
On the use of α‐fetoprotein and prolactin in prenatal diagnosis of fetal abnormalities in early pregnancies
Authors: Bremme K. , Eneroth P. , Nilsson B. 
Published: April 2004

AbstractIn the search for laboratory tests to aid in the diagnosis of fetal malformation we have explored the usefulness of assaying prolactin in amniotic fluid. The results have been compared to those obtained with α‐fetoprotein analyses.
A five year experience with Laparoscopic Falope Ring sterilization
Authors: Meyer Julien H. 
Published: April 2004

AbstractThis report presents the results of a 5‐year series of Laparoscopic Falope Ring tubal sterilizations performed consecutively at a private hospital by the author. It was seen that no special requirements for patient selection were necessary and previous abdominal surgery was not a contraindication for the operation. Laparoscopic tubal occlusions were accomplished in all but one of the 447 cases and banding was not attempted in this case because of bilateral hydrosalpinges. After follow‐up of 6 months to 5.5 years, there have been no pregnancies other than one well documented luteal phase pregnancy. The few complications encountered were mostly of a technical nature and considered minor. With 90% of the patients available for follow‐up there has been no evidence of long‐term adverse effects such as menstrual dysfunction. Thus Laparoscopic tubal occlusion is seen to be a safe, simple and effective means of female sterilization which can be performed by gynecologists trained in laparoscopy.
Pelvic schistosomiasis and infertility
Authors: El‐Mahgoub S. 
Published: April 2004

AbstractThe use of laparoscopy allowed us to diagnose asymptomatic pelvic schistosomiasis in 13 infertile women. The lesion was associated with dense pelvic adhesions in all cases, a defective luteal phase in 23.1% of the women and anovulation in 15.4%. Atraumatic adnexolysis, antibilharzial treatment and correction of ovulatory defects were followed by intrauterine pregnancy in 46% of the patients.
Ectopic pregnancy early diagnosis limitations
Authors: Portuondo JoséA. , Remacha María J. , Llaguno Manuel Roldan 
Published: April 2004

AbstractA series of 219 surgically and pathologic proven ectopic gestations are reviewed to emphasize the ectopic pregnancy early diagnosis limitations. A childbearing age, low parity woman is typical of having an ectopic pregnancy. Risk factors in their past history were absent in 52% of patients. Fertility investigations, IUD, PID, and abdominal surgery are often found in their past. Six per cent of patients had a previous ectopic pregnancy. Sixty‐one per cent of patients were admitted with a definite ruptured ectopic pregnancy and 37% were admitted to rule out this condition. At surgery 58% had ruptured ectopic pregnancy with intraabdominal hemorrhage. Only 12% were unruptured.The obstetric outcome after surgery was available in 74 patients. Out of these, 40.5% had term pregnancies with live children, repeat ectopic pregnancy occurred in 8.2% spontaneous first trimester abortion in 4.1% and subsequent infertility in 16% Postoperative pelvic adhesions were more frequently seen, at laparoscopy, when the patients were diagnosed at the stage of ruptured ectopic pregnancy with intraabdominal hemorrhage. A diagnostic protocol based on the screening of the patients at risk, correct evaluation of symptom and signs, and liberal use of β‐hCG pregnancy test, culdocentesis, ultrasound and laparoscopy, is finally proposed.
Three neuroleptanalgesia schedules for laparoscopic sterilization by electrocoagulation
Authors: Koetsawang Suporn , Srisupandit Suwanee , Kiriwat Orawan , Apimas Supanee J. , Feldblum Paul 
Published: April 2004

AbstractWomen undergoing interval laparoscopic electrocoagulation sterilization were randomly assigned to one of three neuroleptanalgesia regimens. The 299 women received either morphine (10 mg)/droperidol (2.5 mg)/ atropine (0.3 mg) or pethidine (100 mg)/ droperidol (2.5 mg)/atropine (0.3 mg) or pethidine (100 mg)/droperidol (2.5 mg).A significantly higher proportion of anesthesia complications were recorded in the morphine group. The amount of pain experienced by the women was similar in the three groups, as were the rates of early follow‐up complications and complaints. The neuroleptanalgesia regimen containing pethidine/ droperidol/atropine appears to be the safest and most effective of the three considered here.
The safety and efficacy of tubal sterilization: An international overview
Authors: Peterson H.B. , Lubell I. , DeStefano F. , Ory H.W. 
Published: April 2004

AbstractThis article presents a synthesis of some of the major published studies on the efficacy and safety of tubal sterilization. The conclusions of this overview are that tubal sterilization is a safe operation, long‐term sequelae of tubal sterilization have not been well documented, and the risk of pregnancy following tubal sterilization is less than 1 in 100. Continued study is needed to determine how to make a safe and effective procedure even safer and more effective.
Prenatal diagnosis of triploidy
Authors: Chatterjee Molly S. , Tejani Nergesh A. , Verma Uma L. , Weiss Robert R. 
Published: April 2004

AbstractTwo cases of late midtrimester triploid gestation are presented. This unusual condition might be suspected in cases of first and second trimester bleeding when the uterus appears to be unusually large as estimated by the menstrual history. Early presence of gestational hypertension also points suggestively toward a triploid fetus. Ultrasound examination of the placenta typically shows multiple sonolucent areas. Confirmation of diagnosis is made by karyotyping cells obtained from amniotic fluid. The condition is incompatible with life and termination of pregnancy is indicated. It is considered prudent to follow HCG levels for evidence of persistent trophoblastic tissue.
Urinary culture and morbidity in gynecological surgery
Authors: Ohel Gonen , Bahari Charles M. , Edelstein Theodore , Cohen Joel S. 
Published: April 2004

AbstractThree hundred women undergoing gynecological surgery were evaluated as regards post‐operative morbidity and its relationship to urinary tract infections. The incidence of pre‐operative positive urine cultures was 6.3%. This was almost trippled post‐operatively.Post operative morbidity was found in 39% of the cases with the highest rate following vaginal surgery. Urinary tract infection was thought to be the cause in 20% of the cases, wound infection in 42% and unknown among 36% of the cases.It was found that the pre‐ and post‐operative urine cultures were poorly related to morbidity and it was particularly noted that 41% of patients who had positive post‐operative cultures suffered no morbidity at all. It was concluded that the mere finding of positive pos‐operative urine cultures may not have accounted for the morbidity in some of the cases and the need for further search of the cause is discussed.
Determination of biparietal diameter in the second trimester as a predictor of intrauterine growth retardation
Authors: Lee J.N. , Chard T. 
Published: April 2004

AbstractFetal biparietal diameter (BPD) was measured by ultrasound at 18–21 weeks gestation in 1023 women. The results showed a clear relationship to birth weight at delivery (36 weeks or later): the sensitivity was 24.2%, the predictive value was 18.2%, and the specificity was 92.5%. We propose that BPD measured in the second trimester is a clinically useful predictor of intrauterine growth retardation.
Leucocyte metabolism in maternal and cord blood in intrauterine malnutrition (IUM)
Authors: Iyengar Leela R. , Vishwanathan M.K. 
Published: April 2004

AbstractLeucocyte metabolism was studied in maternal and cord blood in normal term pregnancies with and without intrauterine malnutrition (IUM). It was observed that hexose monophosphate shunt activity was significantly reduced in the leucocytes of both the mothers and infants with IUM. Glycogen content in the cord leucocytes was also reduced, indicating a reduction in the defense mechanism in the infants. Protein/DNA ratio was significantly increased in both the maternal and cord leucocytes in IUM. It would appear that IUM, especially in a high‐risk population, can be predicted in early third trimester by using maternal leucocyte protein/DNA.
Intestinal injuries following induced abortion
Authors: Imoedemhe D.A.G. , Ezimokhai M. , Okpere E.E. , Aboh I.F.O. 
Published: April 2004

AbstractSixteen cases of intestinal injuries following illegally induced abortion are reviewed. They constituted 2% of all such cases in the study period. Ten were terminal ileal injuries while six were colonic. Colonic injuries were predominantly encountered in the first trimester. The relative fixity of the terminal ileum and pelvic colon may be a factor in the determination of the site of injury. Morbidity and mortality are related to both gestational age and site of injury.
The effect of oral contraceptive formulation and field‐workers: A cautionary tale
Authors: Miller Peter C. , Donaldson Peter J. , Basnayake Sriani , De Silva S. Victor 
Published: April 2004

AbstractThis paper examines oral contraceptive continuation rates and reported side effects in a large scale clinical research project conducted in Sri Lanka. The project evaluated standard‐ and low‐dose pills used with and without vitamin supplements. Differences in continuation rates and perception of side effects are used to illustrate the impact that family planning field‐workers can have on women's use of oral contraceptives.
A hyperprolactinemic woman with regular ovulatory menstrual cycles
Authors: Miyakawa Isao , Kawano Kyogo , Koike Hiroyuki , Taniyama Keiichi , Mori Norimasa 
Published: April 2004

AbstractA hyperprolactinemic woman with regular menstrual cycles was presented. It may be suggested in this case that immunoassayable plasma prolactin (PRL) with big molecules made up a greater percentage of total PRL than the highly biologically‐active little molecules.
Fetal growth and perinatal mortality in twin pregnancy ‐ effect of sick leave and hospitalization
Authors: Erkkola R. , Ala‐Mello S. , Kero P. , Sillanpää M. 
Published: April 2004

AbstractFetal growth, birth weight specific mortality rates and effect of sick leave or hospitalization on the fetal growth were investigated in a material of 476 twin pregnancies managed at University Central Hospital of Turku in year 1970–1981. Birth weights of twin babies at any gestational age were slightly but not significantly higher than in earlier materials. When compared to growth curve of singleton fetuses, the growth rate of both twins is equal to singletons up to 30th week of pregnancy, being thereafter slower than in singleton pregnancies.Although duration of sick leave and hospitalization increased considerably during the study period, no change in the duration of pregnancy nor in the weight of twin babies occurred. Instead perinatal mortality decreased from 101/per thousand to 36.2/ per thousand. Birth weight specific mortality rates did not differ from those in singleton fetuses.
Induction of labor in postterm pregnant women
Authors: Ekman Gunvor , Persson P.‐H. , Ulmsten Ulf 
Published: April 2004

AbstractWe have studied the outcome of labor induction in 145 postterm pregnant women in whom gestational age was properly assessed by ultrasound scanning. The induction techniques were adapted to the cervical states of the patients. Seventy‐five patients (32 nulliparous and 43 multiparous) with favorable cervical states were successfully induced with intravenous oxytocin. In this group the frequency of Caesarean section was 2%.Seventy patients (45 mulliparous and 25 multiparous) with unripe cervices received 0.5 mg PGE2 in viscous gel intracervically to prime the cervix and to induce labor; 38 (52%) were induced into labor after a single PGE2‐gel application whereas 26 (48%) needed labor augmentation with intravenous oxytocin after PGE2‐gel obtained cervical ripening. In 6 of the 20 patients the cervix did not ripen and the PGE2‐gel application had then to be repeated. The frequency of cesarean sections was 11%.In 5 out of the 145 patients (4%) the fetuses had signs of intrauterine growth retardation (IUGR) as assessed by ultrasound scanning, and postmaturity as verified by pediatric examination at delivery. All these fetuses belonged to nulliparous women with unripe cervices and all had to be delivered instrumentally (3 by cesarean section and 2 by ventouse) indicating the fragility of these children. If postterm pregnancy is complicated by an unfavorable cervical state intracervical application of PGE2‐gel seems to be an efficient method to prime the cervix and to induce labor. In most patients an uncomplicated vaginal delivery can be achieved by this procedure. However, nulliparous women with unfavorable cervices and signs of IUGR constitute a high risk group of patients at labor induction.
Acute polyhydramnios and cord presentation — complication of chorioangioma of the placenta — a case report
Authors: Wong P.C. , Arulkumaran S. , Ratnam S.S. , Pang M. 
Published: April 2004

AbstractChorioangioma of the placenta is an uncommon benign tumor of the placenta. Large tumors are rare and they often cause increased maternal morbidity and fetal morbidity and mortality. A patient with continuous abdominal pain at 29 weeks gestation was clinically diagnosed to have acute polyhydramnios. Multiple pregnancy was suspected because of a tense uterus much larger than the dates and three palpable “fetal poles”. An ultrasound examination revealed the third pole to be a large chorioangioma. She went into premature labor and a cesarean section was performed because of a cord presentation. Both mother and infant had an uneventful recovery. The complications of chorioangioma is discussed.
The effect of an oral contraceptive containing ethinylestradiol and desogestrel on hair growth and hormonal parameters of hirsute women
Authors: Ruutiainen K. 
Published: April 2004

AbstractA group of 22 hirsute women was treated with a combination of 0.030 mg of ethinylestradiol and 0.150 mg of desogestrel (EE‐DG) for 6 or 12 months. After 6 months the hair growth was decreased in 17 patients. There was a significant decrease in testosterone/sex hormone binding globulin (T/SHBG) ratio and serum dehydroepiandrosterone sulphate (DHEAS) levels. The changes in the hirsutism and the T/SHBG ratio showed correlation (rho 0.36, P < 0.05). The patient groups with the best and the poorest clinical response differed in terms of summed changes in the T/SHBG ratio and DHEAS. These findings suggest that the therapeutic effect of the EE‐DG is based on combined changes in the related hormone levels.
Serum ovarian steroids, prolactin and prostaglandin metabolites in women using the inert intrauterine device
Authors: Shalev E. , Harpaz‐Kerpel S. , Engelhard Y. , Weiner E. , Eran A. , Zuckerman H. 
Published: April 2004

AbstractSerum levels of 17β estradiol, progesterone, prolactin and metabolites of prostaglandins E2 and F2a were investigated in 18 healthy women before and after insertion of a Saf‐T‐Coil intrauterine device. The results suggest that the presence of an intrauterine device may cause hormonal changes affecting the luteal phase of the menstrual cycle.
International colloquy on the management of intrauterine fetal death
Authors: Kuhn W. , Rath W. , Sciarra John J. 
Published: April 2004

AbstractManagement of intrauterine fetal death is a common medical problem. The risks of time‐related development of consumptive coagulopathy and intrauterine infection with speticemia force the clinician to terminate pregnancy as soon as possible while still taking into account the mental distress of the patients. Rapid surgical intervention (e.g. hysterotomy) is associated with a considerable risk of maternal morbidity and mortality. The following reports from international experts present a topical survey of current methods for the management of fetal demise. This background of clinical experience from different countries should serve to stimulate discussion on problems associated with intrauterine fetal death and ultimately lead to practical advice that will be of benefit to the patients.
Ectopic pregnancy without laparotomy: defining the incidence of manageable patients
Authors: Sauer M.V. , Rand T.C. , Buster J.E. 
Published: April 2004

AbstractTo assess the incidence of ectopic pregnancies meeting published criteria for laparoscopic or medical therapy, we retrospectively evaluated tubal pregnancies admitted during a 12‐month period. Because 41/121 (34%) were visible laparoscopically, unruptured, and ⩽3 centimeters in diameter, we conclude that substantial numbers of ectopics may be managed without laparotomy.
Ovarian function after the menarche and hormonal contraception
Authors: Borsos A. , Lampé L. , Balogh A. , Csoknyay J. , Ditrói F. , Székely P. 
Published: April 2004

AbstractThe aim of the study was to determine the date of regular ovulation after the menarche to better understand the physiology of female adolescence, especially as it pertains to the use of hormonal contraception. Early morning urine samples were collected from 51 girls in the perimenarche for 9 weeks semi‐annually during 2 years. Estrone‐ and pregnanediol‐3‐glucuronide values were determined. Cycles lasting 35–40 days at the onset of menses shortened to 28 days after the 23rd–25th cycle. Menses reached a 5.0–5.5 day average length at about the same time. After the 20th cycle, ovulation could be demonstrated in more than 50% of the study patients. Using a scoring system, regular ovulation could be expected on the basis of somatic data with scores of > 16. Hormonal contraception may be prescribed 2 years after the menarche, based on scores of > 16 and ovulation proven by hormonal cytology and basal body temperature.
Pregnancy after hemipelvectomy: a case report and review of the literature
Authors: Bergh P.A. , Bonamo J. , Breen J.L. 
Published: April 2004

AbstractHemipelvectomy is a most radical attempt at cure of malignant tumors of the pelvis and the upper portion of the femur. Pregnancy following this severely mutilating operation is rare. Despite the considerable loss of pelvic support patients do remarkably well. A case of pregnancy following hemipelvectomy is presented and represents the 16th report in the English literature. The anatomic consequences of hemipelvectomy are described and a review of the past 61 years experience with pregnancy following this operation is presented.
Serum lactic dehydrogenase isoenzymes alteration in carcinoma cervix uteri
Authors: Kumar M. , Birdi A. , Gupta Y.N. , Gupta S. 
Published: April 2004

AbstractSerum LDH‐isoenzyme studies revealed that in carcinoma cervix, the principal activity was confined to LDH‐2 and LDH‐3 with a significant rise in LDH‐2 fraction when compared with the control values (P < 0.001). Radiotherapy caused significant lowering of LDH‐2 and LDH‐3 (P < 0.001 in each case). There was no relation of LDH‐isoenzyme distribution in different clinical stages and morphological distribution within the tumor. Further, LDH‐2 and LDH‐3 were found to be lowered significantly in good and moderate clinical radiation response (CRR) groups (P < 0.001 in each case) but in poor CRR group no significant change in LDH‐2 and LDH‐3 was observed following radiotherapy. LDH‐isoenzyme determination in carcinoma cervix is very helpful in assessing the treatment response following radiotherapy and thus may be an important prognostic parameter.
Serum methotrexate and human chorionic gonadotropin concentrations during five‐day chemotherapy for low‐risk metastatic gestational trophoblastic neoplasia
Authors: Hilgers R.D. , Standefer J.C. , Bowling M.C. , Greeley P. 
Published: April 2004

AbstractA recent report of serum methotrexate (MTX) levels measured during treatment of gestational trophoblastic neoplasia (GTN) led us to determine MTX and human chorionic gonadotropin (β‐hCG) levels in a patient with low‐risk metastatic GTN with a pulmonary metastasis. Peak MTX concentrations exceeded 10−6 mol/l considered by many investigators to be within the therapeutic range against many human tumors. Serum β‐hCG levels did not decline during MTX administration; however, after 5 days of MTX a steep dose‐response curve was observed which continued during 5 courses of chemotherapy.
How does pre‐eclampsia influence thermal conductivity of the skin?
Authors: Miyamoto S. , Shimokawa H. , Kurokawa T. , Nakano H. 
Published: April 2004

AbstractTo evaluate the thermal conductivity characteristics in relation to pre‐eclampsia, deep body temperature (DBT) was measured using the zero‐heat flow method in non‐pregnant healthy subjects, normal pregnant subjects, pregnant subjects with essential hypertension and in pre‐eclamptics. The duration of the initial rise in peripheral DBT was significantly prolonged in the pre‐eclamptics, as compared with findings in the other three groups. The results indicate that pre‐eclamptics have a decrease of thermal conductivity of the skin.