bluuebunny/crossref_metadata_2025_split huggingface dataset:
For the people by the people: Citizen science web interface for real‐time monitoring of tick risk areas in Finland
Authors: Sormunen Jani J. , Kulha Niko , Alale Theophilus Y. , Klemola Tero , Sääksjärvi Ilari E. , Vesterinen Eero J. 
Published: November 2023

Abstract

Ticks and tick‐borne diseases (TBDs) form a significant and growing threat to human health and well‐being in Europe, with increasing numbers of tick‐borne encephalitis (TBE) and Lyme borreliosis cases being reported during the past few decades. Increasing knowledge of tick risk areas and seasonal activity remains the primary method for preventing TBDs. Crowdsourcing provides the best alternative for rapidly obtaining data on tick occurrence on a national level.

In order to produce and share up‐to‐date data of tick risk areas in Finland, an online platform, Punkkilive (www.punkkilive.fi/en), was launched April 2021. On the website, users can submit and browse tick observations, report tick numbers and hosts, and upload pictures of ticks.

Here, we looked at trends in the crowdsourced data from 2021, assessed the effect of local tick species on seasonality of observations and examined sampling bias in the data.

The high number of tick observations (n = 78,837) highlights that there was demand for such a service. Approximately 97% of 5573 uploaded pictures represented ticks. Seasonal patterns of tick observations varied across Finland, highlighting variability in the risk associated with the two human‐biting tick species Ixodes ricinus and I. persulcatus, the latter having a shorter, unimodal activity peak in late spring–early summer. Tick numbers were low and the proportion of new sightings high in northern Finland, as may be expected near the latitudinal distribution limits of both species. While the number of inhabitants generally explained the number of tick observations well, geographically weighted regression models also identified areas that deviated from this general pattern.

This study offers a prime example of how crowdsourcing can be applied to track vectors of zoonotic diseases, to the benefit of both researchers and the public. Areas with more or less observations than predicted based on number of inhabitants were revealed, wherein more specific analyses may reveal factors contributing to lower or higher risk levels that may be used in increasing awareness. We hope that the success of Punkkilive serves to highlight the usefulness of citizen science in the prevention of vector‐borne diseases.
Photothermally Enhanced Cascaded Nanozyme‐Functionalized Black Phosphorus Nanosheets for Targeted Treatment of Infected Diabetic Wounds
Authors: Wen Chunping , Zhang Yan , Lai Luogen , Zhang Xuan , Liu Yijun , Guo Qiuyan , Peng Rujue , Gao Yating , Zhang Xufei , He Yan , Xu Shan , Qiao Dan , Zheng Pengwu , Pan Qingshan , Zhu Wufu 
Published: November 2023

AbstractDue to the limitations of H2O2 under physiological conditions and defective activity, nanozyme‐catalyzed therapy for infected diabetic wound healing is still a huge challenge. Here, this work designs a novel multifunctional hybrid glucose oxidase (GOx)–CeO2@black phosphorus (BP)/Apt nanosheet that features GOx and CeO2 dual enzyme loading with photothermal enhancement effect and targeting ability for the treatment of infected wounds in type II diabetic mice. Combined with the photothermal properties of the BP nanosheets, the cascade nanozyme effect of GOx and CeO2 is extremely enhanced. The synergistic effect of peroxidase activity and photothermal therapy with targeting aptamer allows for overcoming the catalytic defects of nanozyme and significantly improving in vitro bacterial inhibition rate with 99.9% and 97.8% for Staphylococcus aureus and Escherichia coli, respectively, as well as enhancing in vivo antibacterial performance with the lowest wound remained (0.05%), reduction of infiltration inflammatory cells, and excellent biocompatibility. Overall, this work builds a nanodelivery system with a powerful therapeutic approach, incorporating self‐supplying H2O2 synergistic photothermal and real‐time wound monitoring effect, which holds profound potential as a clinical treatment for infected diabetic wounds.
Microfluidic Encapsulation of Exosomes Derived from Lipopolysaccharide‐Treated Mesenchymal Stem Cells in Hyaluronic Acid Methacryloyl to Restore Ovarian Function in Mice
Authors: Li Yifan , Zhang Hui , Cai Changjun , Mao Jialian , Li Ning , Huang Danqing , Li Shiyuan , Yang Jun , Zhou Jidong , Wang Huan , Zhu Yujuan , Ding Lijun , Sun Haixiang 
Published: November 2023

AbstractPremature ovarian failure (POF) features an upward incidence nowadays, and the human umbilical cord mesenchymal stem cells (hUC‐MSCs)‐derived exosomes (MSC‐Exos) have shown applied values in the recovery of ovarian function. Here, a novel exosome‐encapsulated microcarrier prepared by microfluidic technology for ovarian repair after chemotherapy damage is presented. The exosomes derived from lipopolysaccharide (LPS)‐preconditioned hUC‐MSCs are encapsulated with hyaluronic acid methacryloyl (HAMA) via microfluidic electrospray, which is named HAMA/MSC‐Exos. Attributing to the biocompatibility and semipermeable property of HAMA, the encapsulated exosomes show great viability and controllable release behavior from HAMA. It is demonstrated that in situ transplantation of HAMA/MSC‐Exos can rescue ovarian functions of cyclophosphamide‐induced ovarian failure in mice by increasing ovarian volume, improving the number of antral follicles and restoring fertility. It is believed that the transplantation of HAMA/MSC‐Exos will provide a new concept for the treatment of POF in clinical practice.
Self‐Powering Sensory Device with Multi‐Spectrum Image Realization for Smart Indoor Environments
Authors: Kim Tae Hyuk , Yu Byoung‐Soo , Ko Hyun Woo , Park Na Won , Saeed Muhammad Ahsan , Ahn Jongtae , Jo Suyeon , Kim Dae‐Yeon , Yoon Seon Kyu , Lee Kwang‐Hoon , Jeong Sang Young , Woo Han Young , Kim Hyunwoo J. , Kim Tae Geun , Park JaeHong , Park Min‐Chul , Hwang Do Kyung , Shim Jae Won 
Published: November 2023

AbstractThe development of organic‐based optoelectronic technologies for the indoor Internet of Things market, which relies on ambient energy sources, has increased, with organic photovoltaics (OPVs) and photodetectors (OPDs) considered promising candidates for sustainable indoor electronic devices. However, the manufacturing processes of standalone OPVs and OPDs can be complex and costly, resulting in high production costs and limited scalability, thus limiting their use in a wide range of indoor applications. This study uses a multi‐component photoactive structure to develop a self‐powering dual‐functional sensory device with effective energy harvesting and sensing capabilities. The optimized device demonstrates improved free‐charge generation yield by quantifying charge carrier dynamics, with a high output power density of over 81 and 76 µW cm−2 for rigid and flexible OPVs under indoor conditions (LED 1000 lx (5200 K)). Furthermore, a single‐pixel image sensor is demonstrated as a feasible prototype for practical indoor operating in commercial settings by leveraging the excellent OPD performance with a linear dynamic range of over 130 dB in photovoltaic mode (no external bias). This apparatus with high‐performance OPV‐OPD characteristics provides a roadmap for further exploration of the potential, which can lead to synergistic effects for practical multifunctional applications in the real world by their mutual relevance.
Suppressing Oxidation at Perovskite–NiOx Interface for Efficient and Stable Tin Perovskite Solar Cells
Authors: Li Bo , Zhang Chunlei , Gao Danpeng , Sun Xianglang , Zhang Shoufeng , Li Zhen , Gong Jianqiu , Li Shuai , Zhu Zonglong 
Published: November 2023

AbstractInorganic nickel oxide (NiOx) is an ideal hole transport material (HTM) for the fabrication of high‐efficiency, stable, and large‐area perovskite photovoltaic devices because of its low cost, stability, and ease of solution processing. However, it delivers low power conversion efficiency (PCE) in tin perovskite solar cells (TPSCs) compared to other organic HTMs. Here, the origin of hole transport barriers at the perovskite–NiOx interface is identified and a self‐assembled monolayer interface modification is developed, through introducing (4‐(7H‐dibenzo[c,g]carbazol‐7‐yl)ethyl)phosphonic acid (2PADBC) into the perovskite–NiOx interface. The 2PADBC anchors undercoordinated Ni cations through phosphonic acid groups, suppressing the reaction of highly active Ni≥3+ defects with perovskites, while increasing the electron density and oxidation activation energy of Sn at the perovskite interface, reducing the interface nonradiative recombination caused by tetravalent Sn defects. The devices deliver significantly increased open‐circuit voltage from 0.712 to 0.825 V, boosting the PCE to 14.19% for the small‐area device and 12.05% for the large‐area (1 cm2) device. In addition, the 2PADBC modification enhances the operational stability of NiOx‐based TPSCs, maintaining more than 93% of their initial efficiency after 1000 h.
Electrode Treatments for Redox Flow Batteries: Translating Our Understanding from Vanadium to Aqueous‐Organic
Authors: Agarwal Harsh , Roy Esha , Singh Nirala , Klusener Peter A.A. , Stephens Ryan M. , Zhou Qin Tracy 
Published: November 2023

AbstractRedox flow batteries (RFBs) are a promising technology for long‐duration energy storage; but they suffer from inefficiencies in part due to the overvoltages at the electrode surface. In this work, more than 70 electrode treatments are reviewed that are previously shown to reduce the overvoltages and improve performance for vanadium RFBs (VRFBs), the most commercialized RFB technology. However, identifying treatments that improve performance the most and whether they are industrially implementable is challenging. This study attempts to address this challenge by comparing treatments under similar operating conditions and accounting for the treatment process complexity. The different treatments are compared at laboratory and industrial scale based on criteria for VRFB performance, treatment stability, economic feasibility, and ease of industrial implementation. Thermal, plasma, electrochemical oxidation, CO2 treatments, as well as Bi, Ag, and Cu catalysts loaded on electrodes are identified as the most promising for adoption in large scale VRFBs. The similarity in electrode treatments for aqueous‐organic RFBs (AORFBs) and VRFBs is also identified. The need of standardization in RFBs testing along with fundamental studies to understand charge transfer reactions in redox active species used in RFBs moving forward is emphasized.
Impact of thoracic shape on the surgical outcomes of laparoscopic‐assisted living donor hepatectomy
Authors: Tanaka Kosuke , Ogiso Satoshi , Yoh Tomoaki , Abdelhafez Ahmed Hussein , Masano Yuki , Okumura Shinya , Kageyama Shoichi , Ito Takashi , Hata Koichiro , Hatano Etsuro 
Published: November 2023

AbstractBackgroundAlthough laparoscopic‐assisted donor hepatectomy (LADH) has become the definitive procedure for harvesting living donor livers, its surgical outcomes in association with donor body shape have not been elucidated.MethodsThe impact of donor factors, including thoracic shape, on LADH outcomes was retrospectively investigated. Thoracic anthropometric data were examined in all LADHs with a left/right graft between 2013 and 2022.ResultsThe study included 210 LADHs, consisting of 106 left‐ and 104 right‐lobe donors with similar blood loss and similar operation time. Males have greater thoracic depth and greater thoracic width compared with females, respectively. Thoracic depth was associated with graft weight (p < 0.001), blood loss (p < 0.001), and operation time (p < 0.001). On multivariate analyses, blood loss >500 mL and operation time >8 h were associated with graft weight in the left‐lobe donors, and blood loss >500 mL was associated with thoracic depth in the right‐lobe donors.ConclusionThe greater thoracic depth is associated with massive blood loss in right‐lobe donors. Anthropometric parameters might be helpful for estimating LADH outcomes.
A novel multifunctional phosphorous and nitrogenous reactive flame retardant toward epoxy resins by one‐pot method
Authors: Zhang Heng , Peng Yunyan , Xiao Youhua , Kong Shuai , He Xingwei , Liu Lina , Lou Gaobo , Kuang Yi , Fu Shenyuan , Rao Qingqing 
Published: November 2023

AbstractEpoxy resin (EP) has attracted considerable attention in packaging, electronic devices, aerospace, and coatings fields owing to its remarkable chemical and physical performance. However, the inherent flammable performance and unfavorable brittle nature seriously restricted its application in sophisticated industry. Herein, an efficient reactive 9,10‐dihydro‐9‐oxa‐10‐phosphaphenanthrene‐10‐oxide (DOPO)‐based flame retardant (DB‐DAD) was prepared by a facile “one‐pot” method. Due to their synergistic gas‐phase and solid‐phase flame‐retardant effects, DB‐DAD modified EP composites (EP/DB‐DAD composite) easily achieved UL‐94 V‐0 ratings, and an EP/DB‐DAD composite with a 0.32 wt% phosphorus content had an excellent (30.2%) limiting oxygen index. In addition, the amounts of heat and smoke decreased by 28.1% and 24.8%, respectively. Due to the introduction of long and flexible aliphatic chains, the EP/DB‐DAD composites exhibited satisfactory mechanical properties, the flexural and tensile toughness of EP/6% DB‐DAD were 82.5% and 62.2% higher than those of neat EP, respectively. Furthermore, EP/DB‐DAD composite showed good transparency (>85%) and favorable UV shielding performance. The EP/DB‐DAD composite with good comprehensive performance is extremely promising to accelerate EP application in high‐tech industries.
Sustainable and biodegradable poly(butylene succinate‐co‐terephthalate)/poly(propylene carbonate) blown films with enhanced compatibility, mechanical, and barrier properties
Authors: Liu Chengkai , Chen Ling , Yan Xiangyu , Dong Xianling , Tian Hanlin , Pan Hongwei , Wang Dongmei , Zhao Yan , Zhang Huiliang 
Published: November 2023

AbstractIn this study, a novel environment‐friendly PBST/PPC‐based blown film was prepared using maleic anhydride (MA) as a reactive compatibilizer to enhance the compatibility between poly(butylene succinate‐co‐terephthalate) (PBST) and poly(propylene carbonate) (PPC). Results of rheological testing and gel permeation chromatography (GPC) indicated that MA reacted with PBST/PPC during melt‐blending extrusion. Morphological analysis of the cryo‐fractured surfaces of PBST/PPC blend showed significantly improved compatibility between PBST and PPC with the addition of MA. Moreover, the Young's modulus, tensile strength, breaking strain, and tear strength of PBST/PPC/MA blown films increased with an increase in MA content. In comparison to PBST/MA blown film without PPC, the barrier property of PBST/PPC/MA blown films was improved. In addition, in vitro cell experiments showed that the PBST/PPC/MA blown film was suitable for the growth of mouse fibroblast (L929) cells. In vitro ecotoxicity testing on mung bean plant showed that the extracts from the PBST/PPC/MA blown film had no negative effects on the development of mung bean plant. Furthermore, degradability testing in soil also proved that the PBST/PPC/MA blown film had good biodegradability. Thus, the PBST/PPC/MA blown film can be used in fields, such as food packaging and agricultural mulch film.
Variations in body condition of green turtles (Chelonia mydas) in two nearby foraging grounds indicate their sensitivity to foraging habitats
Authors: Nishizawa Hideaki , Joseph Juanita , Jolis Gavin , Isnain Irwan , Muin Hussien , Johari Sofia , Saleh Ejria 
Published: November 2023

Abstract

Coastal seagrass habitats are critical foraging grounds for endangered green turtles (Chelonia mydas). However, these habitats are vulnerable to anthropogenic effects, potentially leading to their degradation with consequent impacts on the health status of foraging green turtles.
Two foraging habitats of green turtles in Tun Mustapha Park, Sabah, Malaysia were surveyed: Kudat Mainland and Balambangan Island, by capturing green turtles and evaluating their physical body condition as well as assessing seagrass cover.
Despite having similar genetic compositions, the Kudat Mainland aggregation had significantly higher body size (curved carapace length: 61.7 ± 14.5 cm, body weight: 30.0 ± 22.2 kg), Fulton's body condition index (BCI: 1.49 ± 0.13), barnacle (Chelonibia testudinaria) occurrence (78.8%) and barnacle abundance (5.46 ± 9.90 barnacles/turtle) than the Balambangan Island aggregation (curved carapace length: 51.6 ± 8.1 cm, body weight: 17.3 ± 7.7 kg, BCI: 1.40 ± 0.09, barnacle occurrence: 31.0%, barnacle abundance: 0.50 ± 0.92 barnacles/turtle). The differences in BCI between the nearby aggregations could not be attributed to size and barnacle occurrence differences, suggesting the foraging habitat is the primary factor affecting the body condition of green turtles.
Seagrass cover at Kudat Mainland was only slightly higher than at Balambangan Island. These findings suggest that the body condition of green turtles is potentially sensitive to the quality of foraging habitats such as nutrients and water quality.
It is crucial to monitor the health of foraging habitats and their impact on the body condition of turtles. It is recommended that habitat‐turtle dynamics are given conservation priority, in parallel to water quality monitoring – with action taken to reduce pollution if necessary. A holistic approach to turtle conservation is therefore required.
Exploring online sustainability disclosure in the healthcare industry: Evidence from best international hospitals
Authors: Garzoni Antonello , L'Abate Vitiana , Raimo Nicola , Vitolla Filippo 
Published: November 2023

AbstractSociety's growing attention to sustainability has also brought about major challenges for the healthcare sector. In particular, hospitals by virtue of their function are also called to incorporate social and environmental issues in the undertaking of their activities. In this scenario, hospitals must also provide a correct representation of these issues through an adequate sustainability disclosure. However, despite the relevance of the topic, it is still little explored in the academic field. This study aims to fill this important gap by investigating the determinants of online sustainability disclosure through a legitimacy theory perspective. The econometric analysis, conducted on a sample of the best hospitals in the world, highlights a low level of dissemination of sustainability information. Furthermore, it demonstrates a positive impact of the size, public status and teaching status of hospitals on the amount of sustainability information disclosed by these institutions through their website.
Charity ugliness premium: Donors' empathy for unattractiveness during the COVID‐19 pandemic and implications for charity advertising
Authors: Yu Ziyue , Yang Shuai , Zheng Hualu , Chang Xinyu 
Published: November 2023

AbstractMarketers and policymakers use advertising visuals to motivate prosocial behavior, whereby visual attractiveness influences people's empathy and thus their prosocial decisions. In the charity context, various donor‐related factors, including external circumstances and environments in which donors find themselves, can determine the impact of visual attractiveness. In two studies, this research investigates how and why donors responded to attractive/unattractive charitable images during the universal hardship of the COVID‐19 pandemic. In the first study, field data from a charity platform reveal how visual aesthetics affected donations before and during the pandemic. In the second study, a laboratory experiment examines empathy as a mediator of the relationship between visual attractiveness and charitable purchase intentions before and during the pandemic. During the pandemic, unattractive visuals generated significantly greater empathy than attractive visuals, and empathy drove donations and purchase intentions for charitable goods. That is, the “ugliness premium” dominated the “beauty premium” during the pandemic. Our findings that natural disasters or crises moderate observers' preferences for visual attractiveness or unattractiveness offer meaningful insights for applying visual aesthetics to charity advertising designs.
Three New Clerodane Diterpenoids and Their NLRP3 Inflammasome Activation Inhibitory Activity from Callicarpa arborea Roxb
Authors: Zeb Muhammad Aurang , Ding Ling , Wang Meng‐Ru , Tu Wen‐Chao , Li Xiao‐Li , Zhang Xing‐Jie , Xiao Wei‐Lie 
Published: November 2023

AbstractThree new compounds callicarpenoids A−C (1–3), were isolated from the stems of Callicarpa arborea Roxb together with fifteen known compounds (4–18). The structures of these compounds were elucidated using advanced spectroscopic techniques, including 1D and 2D NMR, UV, IR, HR‐ESI‐MS, ECD, and quantum chemical calculations. Compound 3, a rare rearranged diterpenoid with a fused 5/6‐ring system demonstrated strong potential as an inhibitor of the NLRP3 inflammasome activation with an IC50 value of 3.153 μM. It effectively reduced GSDMD‐NT production, inhibited caspase‐1 activation, and suppressed IL‐1β secretion, thereby mitigating NLRP3 inflammasome‐induced pyroptosis in J774A.1 cells. These findings suggest that compound 3 warrants further research and development as a promising NLRP3 inflammasome inhibitor.
A tale of two in stent restenosis in same patient: Surprising findings from optical coherence tomography
Authors: Pradhan Akshyaya , Roy Shubhajeet , Chaudhary Gaurav , Vishwakarma Pravesh , Chandra Sharad , Hasibuzzaman Md. Al 
Published: November 2023

Key Clinical MessageThe morphology of in‐stent restenosis (ISR) in drug eluting stents varies greatly from that of bare metal stents. Optical coherence tomography (OCT) is a useful aid for identifying the nature of ISR and planning the treatment accordingly, which may be by intravascular lithotripsy, cutting balloon or Rotablator, which can be used upfront if OCT shows calcified neoatherosclerosis.AbstractRestenosis is the decrease in the diameter of the vessel lumen after the performance of percutaneous intervention (PCI), which may or may not involve the implantation of a stent. The morphology of in‐stent restenosis (ISR) in drug eluting stents (DES) vary greatly from that of bare metal stents (BMS). We present the case of a 60‐years‐old lady, who was a follow up case of PCI of the left anterior descending artery with DES and left circumflex artery using BMS 16 years ago. Optical coherence tomography (OCT) revealed both neoatherosclerosis and neointimal hyperplasia in both DES as well as BMS. The morphology of ISR in DES differed from that of BMS. PCI and pharmacological strategies form the main stream of management in case of neointimal hyperplasia. Detection of pattern of ISR on OCT can direct the management of a particular patient, which may be by the use of adjunct devices like intravascular lithotripsy, cutting balloon and Rotablator, which can be used upfront if OCT shows calcified neoatherosclerosis.