bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical evaluation of a cryptococcal antigen latex agglutination test for diagnosis of cryptococcosis in cats
Authors: Medleau Linda , Marks M. Amanda , Brown John , Borges Wendy L. 
Published: December 2023

Summary
A commercial cryptococcal antigen latex agglutination test was used to evaluate sera from 20 cats with cryptococcosis and 184 cats without cryptococcosis. Cryptococcal antigen was detected in the sera from 19 of 20 cats with cryptococcosis. Antigen was not detected in sera from any of the cats without cryptococcosis. The test had sensitivity of 95% and specificity of 100%.
Prevalence and effect of subclinical ovine progressive pneumonia virus infection on ewe wool and lamb production
Authors: Snowder Gary D. , Gates Norman L. , Glimp Hudson A. , Gorham John R. 
Published: December 2023

Summary
The prevalence of infection with ovine progressive pneumonia (opp) virus and its effects on ewe wool and lamb production were investigated in a flock of 2,976 ewes of 6 breed types (Rambouillet, Targhee, Columbia, Polypay, ¼ cross Finnsheep, and ½ cross Finnsheep). Prevalence of seropositivity was significantly (P ≤ 0.01) lower among Rambouillet and Targhee breeds (44 and 42%, respectively), intermediate in Polypay, Columbia, and ¼ cross Finnsheep (approximately 53%), and higher among ½ cross Finnsheep (62%). Seropositivity increased with age in all breed types from ll% at l year of age to 93% at ≥ 7 years of age. Lateral disease transmission is indicated by linear increase of seropositivity prevalence with increasing age, including that in sheep > 6 years old. Subclinical infection with opp virus had no apparent detrimental effect on number of lambs born, lamb viability, birth weight, number of lambs weaned, or growth rate of single and twin lambs, compared with findings for noninfected sheep in the same flock. Mature ewe body weight and grease fleece weight did not differ between subclinically infected seropositive and seronegative ewes. Subclinical infection with opp virus does not appear to have an adverse economic effect on ewe wool and lamb production. Culling rate attributable to clinical manifestation of infection with opp virus must be accurately determined before the true effects of virus infection on production can be determined and an eradication program can be recommended.
Infiltrative urethral disease in female dogs: 41 cases (1980-1987)
Authors: Moroff Scott D. , Brown Bonnie A. , Matthiesen David T. , Scott Richard C. 
Published: December 2023

Summary
Forty-one cases of infiltrative urethral disease in female dogs were reviewed. The cause was epithelial neoplasia in 29 dogs, granulomatous (chronic active) urethritis in 10 dogs, and leiomyoma in 2 dogs. Clinical signs of disease were similar in dogs with neoplastic and inflammatory disease and included strangury (36/41), hematuria (30/41), pollakiuria (20/41), vaginal discharge (16/41), and complete urinary obstruction (7/41). Results of aspiration biopsy of the urethra correlated with those of surgical biopsy in 11 of 15 dogs. In 4 of 15 dogs, results of cytologic and histologic examinations differed. Granulomatous (chronic active) urethritis is an infiltrative urethral disease in female dogs. Clinical findings are similar, but the prognosis is more favorable than that in dogs with urethral epithelial neoplasia.
Hepatotoxicity of phenobarbital in dogs: 18 cases (1985-1989)
Authors: Dayrell-Hart Betsy , Steinberg Sheldon A. , VanWinkle Thomas J. , Farnbach George C. 
Published: December 2023

Summary
The medical records of 18 dogs that had hepatic disease and received phenobarbital as an anticonvulsant for 5 to 82 months were reviewed. Clinical signs included sedation and ataxia in all dogs, 5 dogs were also anorectic, 2 had coagulopathy, 3 were icteric, and 5 had ascites. Serum biochemical analysis revealed serum albumin concentration ≤ 2.2 g/dl in 12 dogs, serum alkaline phosphatase activity ≥ 169 U/L in 18 dogs, serum alanine transaminase activity ≥ 57 U/L in 15 dogs, and total bilirubin concentration ≥ 1 mg/dl (in the absence of lipemia) in 7 dogs.
Serum phenobarbital concentration was ≥ 40 μg/ml in 12 of 17 dogs. Sulfobromophthalein excretion was prolonged in 8 of 10 dogs. Preprandial serum bile acid concentrations were high in 8 of 10 dogs, and 2-hour postprandial serum bile acid concentrations were high in 9 of 10 dogs. Two of 4 dogs tested had resting plasma ammonia concentrations > 200 mg/dl. An ammonia tolerance test was performed on 2 other dogs; both had ammonia concentration ≥ 200 mg/dl in the plasma 30 minutes after receiving 100 mg of ammonium chloride/kg of body weight, po.
Nine dogs died, 1 was euthanatized, and necropsies were performed on these 10 dogs. Biopsies and necropsies of 6 dogs revealed chronic hepatic fibrosis with nodular regeneration (cirrhosis). One dog had hepatocellular carcinoma and mild cirrhosis. In 1 dog, after phenobarbital had been withheld, necropsy revealed complete recovery of the previously observed lesions.
Use of western blot and radioimmunoprecipitation for diagnosis of feline leukemia and feline immunodeficiency virus infections
Authors: Egberink Herman F. , Lutz Hans , Horzinek Marian C. 
Published: December 2023

Summary
The uses and limitations of the western blot (wb) and radioimmunoprecipitation assay (ripa) techniques for study of feline immunodeficiency virus (fiv) and FeLV were evaluated. Western blot analysis was used to detect antigenic relatedness between the 2 lentiviruses. Using a rabbit serum directed against p26 of the equine infectious anemia virus (eiav) and anti-eiav horse serum obtained from an infected horse, cross-reactivity with p24 of fiv was revealed. Cat sera obtained late after experimentally induced fiv infection recognized p26 of eiav, which indicates reciprocal cross-reactivity.
Seroprevalence of babesiosis in Greyhounds in Florida
Authors: Taboada Joseph , Harvey John W. , Levy Michael G. , Breitschwerdt Edward B. 
Published: December 2023

Summary
An indirect fluorescent antibody test was used to serologically survey Greyhounds from 10 kennels that are part of the racing Greyhound industry in Florida. Age of dogs ranged from 11 months to 11 years. Additionally, 50 adult non-Greyhound pet dogs were consecutively surveyed. Of 393 Greyhounds tested, 181 (46%) were seropositive for babesiosis; pet dogs were seronegative. Slightly higher percentage of seropositive males than females was observed, but this difference was only significant (P < 0.01) in the 2- to 5-year age class. Male dogs <2 years old had significantly (P < 0.01) lower seroprevalence than did male dogs >2 years old. All 46 Greyhounds that were actively racing at the time of sample collection were seronegative.
Dogs were classified into 2 groups on the basis of whether the kennel owner had sought veterinary attention for anemic pups. The 5 kennel owners that had sought veterinary attention (group A) had significantly (P < 0.01) higher seroprevalence (78.5%), compared with the 5 that had not sought veterinary attention (group B; 23.0%).
Seroprevalence of babesiosis in Greyhounds in Florida was comparable to that reported in a limited survey of other southeastern states. It appears to be higher than that in the pet population. Breeding kennels in Florida and other southeastern states from which anemic pups originate should be screened for babesiosis.
Comparison of diazepam with progestin for effectiveness in suppression of urine spraying behavior in cats
Authors: Cooper Leslie , Hart Benjamin L. 
Published: December 2023

Summary
The most common treatment for urine spraying and marking in cats has been administration of long-acting progestins. Treatment with diazepam has recently been gaining favor, particularly because of reported adverse effects of progestins. Results of a clinical trial involving 20 cats indicated that diazepam was effective in eliminating or markedly reducing spraying in 11 (55%) of them. However, most cats required continuous treatment, or at least intermittent treatment, when spraying recurred. The physiologic and behavioral dependency of cats on diazepam, which presumably develops over the course of administration, may contribute to the tendency for spraying to recur once diazepam treatment is discontinued. Using data from previously published findings on progestin administration, plus additional cases, it was documented that a significantly (P < 0.05) higher percentage of males than females responded favorably. Although the number of cases was not sufficient for a statistical comparison of diazepam vs progestin treatment with regard to male vs female, possible gender difference in the effectiveness of diazepam was not indicated.
Cryptorchidism and monorchism in cats: 25 cases (1980-1989)
Authors: Millis D. L. , Hauptman J. G. , Johnson C. A. 
Published: December 2023

Summary
Of 1,345 cats admitted for orchiectomy during a 10-year period, 23 (1.7%) were cryptorchid and 2(0.1%) were monorchid. Persian cats were overrepresented in the cryptorchid population (P = 0.01). Cats were more likely to be unilaterally than bilaterally cryptorchid (P = 0.01). A predisposition for location of undescended testes (abdominal vs inguinal or right vs left side) was not identified in unilateral cryptorchids. All bilateral cryptorchids had abdominally located testes. The most common surgical approaches used for orchiectomy of cryptorchid cats were a caudal ventral midline incision for inguinal testes and a caudal ventral midline celiotomy for abdominal testes.
Correlation between thoracic radiographs and postmortem findings in dogs with hemangiosarcoma: 77 cases (1984-1989)
Authors: Holt David , Van Winkle Tom , Schelling Curtis , Prymak Caroline 
Published: December 2023

Summary
Thoracic radiographic and postmortem findings were compared in dogs with histologically confirmed hemangiosarcoma (hsa). On the basis of results of radiography, a false-negative diagnosis was made for pulmonary hsa in 10 (2 1.7%) of 46 dogs, and in 26 (53.1%) of 49 dogs for cardiac hsa. The incidence of false-negative radiographic diagnosis for pulmonary hsa was lower in dogs when left and right lateral views were obtained. The radiographic sensitivity was 78%, and the negative-predictive value was 74% for pulmonary hsa. The radiographic sensitivity was 47%, and the negative-predictive value was 43% for cardiac hsa.
Clinical evaluation of axial pattern skin flaps in dogs and cats: 19 cases (1981-1990)
Authors: Trevor Peter B. , Smith Mark M. , Waldron Don R. , Hedlund Cheryl S. 
Published: December 2023

Summary
Nineteen axial pattern skin flaps were used in 16 dogs and cats to provide skin for repair of extensive cutaneous defects. Retrospective evaluation of medical records was used to determine percentage flap survival, postoperative complications, and long-term outcome of axial pattern skin flaps. The most common indication for use of axial pattern flaps was to augment wound closure following tumor resection (n = 7). Other indications included trauma (n = 5), chronic nonhealing wounds (n = 4), urine-induced cellulitis (n = 1), idiopathic dermal necrosis (n = 1), and chronic lymphoplasmocytic dermatitis (n = 1). Mean flap survival (± sd) was 96% (± 8). Postoperative complications included wound drainage (n = 15), partial dehiscence of the sutured flap (n = 7), distal flap necrosis (n = 6), infection (n = 3), edema (n = 3), and seroma formation (n = 2). After a median follow-up time of 5 months, evaluation of animals indicated that surgery provided successful wound reconstruction with good cosmetic results. Reconstruction of large cutaneous defects is facilitated by axial pattern flap application regardless of cause of wound. Postoperative complications are common but amenable to standard wound management techniques such as drain placement and surgical debridement of devitalized distal flap skin.
Tarsal lameness of dairy bulls housed at two artificial insemination centers: 24 cases (1975-1987)
Authors: Bargai Uri , Cohen Robert 
Published: December 2023

Summary
Degenerative joint disease of the tarsi was diagnosed in 20 of 24 Holstein bulls with tarsal lameness at 2 artificial insemination centers from 1975 to 1987. Each of the 2 centers housed about 100 bulls/yr. Of the 24 bulls with tarsal lameness, 22 were from the artificial insemination center designated as A, and 2 were from the center designated as B. Examination of the housing and management procedures revealed that center A had concrete floors with cuboi-dal-shaped yards, whereas center B had deep sand flooring, with long, narrow yards. The only other difference between the 2 centers was that center A used 1- and 2-year-old bulls as teasers for older, heavier bulls to mount, whereas center B used, bulls that were at least 6 years old to withstand the stress placed on their hind limbs by the weight of bulls undergoing semen collection. Radiographic lesions of tarsi of bulls from both centers ranged from distention of the tibiotarsal joint pouch to hypertrophic degenerative osteoarthritis of the distal, intertarsal, and tarsometatarsal joints. It was concluded that the concrete flooring and the semen collecting practices were responsible for the high prevalence of tarsal lameness and degenerative joint disease of the tarsi in bulls housed at center A.
Production, characterization, and applications of a murine monoclonal antibody to dog erythrocyte antigen 1.1
Authors: Andrews Gordon A. , Chavey Patricia S. , Smith Joseph E. 
Published: December 2023

Summary
A murine IgM monoclonal antibody, which recognizes dog erythrocyte antigen (dea) 1.1, has been produced. The antibody correctly identified canine rbc possessing dea 1.1 in a panel of rbc typed by an independent laboratory. Reactivity of the monoclonal antibody was compared with canine anti-dea 1.1 antiserum with 163 rbc samples from 145 dogs. Results of agglutination tests with the 2 reagents were in agreement for all samples. A card agglutination test that uses the monoclonal antibody with blood is described. A monoclonal antibody-based test should facilitate blood typing for dea 1.1 in clinical practice.
Effect of flunixin meglumine and cimetidine hydrochloride on the pH in the third compartment of the stomach of llamas
Authors: Drew Mark L. , Ramsay Ed , Fowler Murray E. , Kass Philip H. 
Published: December 2023

Summary
A Tigon fistula was surgically implanted into the third compartment of the stomach of 5 llamas to allow measurement of gastric pH. The llamas were allotted into 2 groups and given flunixin meglumine or cimetidine hydrochloride for 3 days. After 4 days without treatment, the drugs given to each group were reversed. Measurements of gastric pH were taken every 30 minutes for 6 hours, using an automated pH meter. The pH measurements after drug administration were compared with measurements obtained during a pretreatment control period. Gastric pH during pretreatment control periods had a mean of 1.43 ± 0.063 (mean ± se). The use of flunixin did not significantly decrease gastric pH, compared with pretreatment controls. Gastric pH was significantly higher within the first 30 minutes after administering cimetidine, compared with pretreatment controls, but this difference disappeared at all later times.
Radiographie, epidemiologie, and clinical aspects of simultaneous pleural and peritoneal effusions in dogs and cats: 48 cases (1982-1991)
Authors: Steyn Phillip F. , Wittum Thomas E. 
Published: December 2023

Summary:
In this study, we found that the rate at which radiographically diagnosed simultaneous pleural and peritoneal effusions (double effusions [de]) developed was highest in dogs and cats with infectious causes of pleuritis and/or peritonitis and in those with pancreatitis. However, de were observed more frequently in dogs and cats with neoplastic and cardiovascular diseases. Nonneoplastic liver disease was also documented as a cause of de in the population of this study. Frequency of de was increased in males and in animals > 6 years old. The finding of simultaneous pleural and peritoneal effusions can be considered an indicator of disease severity, and warrants a poor to grave prognosis.
Heritability estimations of osteochondrosis in the tibiotarsal joint and of bony fragments in the palmar/plantar portion of the metacarpo- and metatarsophalangeal joints of horses
Authors: Grϕndahl A. M. , Dolvik N. I. 
Published: December 2023

Summary
Radiography of the tibiotarsal and metacarpo- and metatarsophalangeal joints was performed on 753 Standardbred trotters (6 to 21 months old) born in 1988. The surveyed population was drawn at random from all parts of Norway and represented about 60% of Standardbred trotters born the same year. Osteochondrosis in the tibiotarsal joint was diagnosed in 108 (14.3%) horses, and the prevalence of disease in progeny groups > 10 ranged from 0 to 69%. Bony fragments in the palmar/plantar portion of the metacarpo- and metatarsophalangeal joints were diagnosed in 89 (11.8%) horses, and the prevalence of disease in progeny groups > 10 ranged from 0 to 41%. Heritability analysis was restricted to 644 horses, comprising groups of 5 or more progeny, from 39 stallions. The heritabilities of osteochondrosis in the tibiotarsal joint and of bony fragments in the palmar/ plantar portion of the metacarpo- and metatarsophalangeal joints were estimated to be 0.52 and 0.21, respectively, using a nonlinear model.
Effectiveness of buspirone on urine spraying and inappropriate urination in cats
Authors: Hart Benjamin L. , Eckstein Robert A. , Powell Karen L. , Dodman Nicholas H. 
Published: December 2023

Summary
The most frequent type of behavior problem in cats for which veterinary consultation is sought is problem urination. Urine spraying and urine marking have been treated by use of long-acting progestins and diazepam, a benzodiazepine antianxiety drug. Effectiveness of the nonbenzodiazepine antianxiety drug, buspirone, in suppressing urine spraying and marking in 47 male and 15 female cats was evaluated. The effect of the drug in correcting inappropriate urination in 9 cats also was evaluated. Buspirone resulted in a favorable response (> 75% reduction) in 55% of cats treated for urine spraying or marking. There was no sex difference in effectiveness of the treatment, but cats from single-cat households responded favorably significantly (P < 0.001) less frequently than those from multiple-cat households. The 55% response rate was within the range of treatment effectiveness that has been reported for diazepam, and was greater than that reported for progestin. In contrast to diazepam, with which over 90% of treated cats resumed spraying or marking when the drug was gradually discontinued, only half of the cats treated with buspirone resumed spraying when the drug was discontinued after 2 months of treatment (P < 0.001). This difference between diazepam and buspirone in resumption of urine spraying was attributed to diazepam's induction of physiologic and behavioral dependency, not found with buspirone. Cats that resumed spraying were placed on long-term treatment ranging from 6 to 18 months. Buspirone also did not cause the adverse effects of sedation and ataxia, which commonly are seen with diazepam treatment. In cats treated for inappropriate urination, 56% returned to normal litter box usage. Buspirone appeared to be the drug of choice for treating urine spraying and urine marking, and when combined with appropriate behavioral measures, buspirone is indicated for inappropriate urination as well.
Evaluation of mitoxantrone for the treatment of lymphoma in dogs
Authors: Moore Antony S. , Ogilvie Gregory K. , Ruslander David , Rand William S. , Cotter Susan M. , Getzy David M. , L'Heureux Deborah A. , Dennis Robinette A. 
Published: December 2023

Summary
Mitoxantrone was administered to 74 dogs with lymphoma at a dosage of 5.0 mg/m2 of body surface, IV, every 3 weeks. Thirty-four dogs had failed to respond to prior treatment with chemotherapeutic agents, which included doxorubicin (33 dogs). The remaining 40 dogs had not received prior treatment.
Complete remission was determined in 19 of 74 dogs (26%), 10 of which had not received prior treatment. The median duration of remission for these 10 dogs was 94 days (range, 49 to 440 days, with 2 dogs still alive at 370 and 440 days, respectively). Nine dogs that had received prior treatment had complete remission that lasted for a median of 126 days (range, 42 to 792 days, with 1 dog still alive at 792 days). The combined remission rate (complete remission plus partial remission) was 41%. Toxicosis was minimal, developing in only 9 dogs and requiring hospitalization of 2 dogs.
We concluded that the complete remission rate ascertained when mitoxantrone was the only treatment administered was low, compared with treatments that involved other chemotherapeutic agents; however, the combined remission rate of 41% indicated that mitoxantrone may be beneficial in the treatment of lymphoma in dogs.
Comparison of postoperative phacoemulsification results in dogs with and without diabetes mellitus: 153 cases (1991–1992)
Authors: Bagley Lawrence H. , Lavach J. D. 
Published: December 2023

Summary
Data were collected from the medical records of 123 nondiabetic dogs (182 eyes) and 30 diabetic dogs (57 eyes) in which phacoemulsification surgery was performed. Pre- and postoperative comparisons, including signalment, initial ophthalmic examination findings, surgical variables, and postoperative findings for the short-term follow-up period (mean, 5.75 weeks), between nondiabetic and diabetic dogs revealed that the complication rate was not greater in the diabetic group. Postoperative uveitis was evident with nearly equal frequency (in nondiabetic dogs, 90% or 164 of 182 eyes and in diabetic dogs, 88% or 50 of 57 eyes). In nondiabetic dogs, 1% prednisolone ophthalmic solution and prednisone were administered pre-and postoperatively, and amoxicillin and dichlorphen-amide postoperatively. In diabetic dogs, the same treatment regimen, except for treatment with flunixin meglumine iv at surgery and substitution of aspirin for prednisone, was used. When nondiabetic and diabetic dogs were treated according to their respective pre- and postoperative medical regimens, clinical differences in postoperative findings were not apparent.
Use of bone marrow serum for biochemical analysis in healthy cats
Authors: Dhein Cheryl R. , Barbee David D. 
Published: December 2023

Summary
Bone marrow blood and venous blood were collected from 21 healthy cats for analysis of 13 serum biochemical variables. The relationship between values in venous serum and bone marrow serum for each variable was evaluated, using a linear regression F test. A P value ≤ 0.05 was considered significant evidence that measurements in venous and marrow serum were correlated for that biochemical variable. Biochemical variables for which values were significantly correlated included urea nitrogen, creatinine, cholesterol, total protein, albumin, sodium, chloride, and phosphorus concentrations. In all cats, activities for alanine transaminase and alkaline phosphatase in bone marrow serum exceeded the activities in venous serum. Potassium and phosphorus concentrations were greater in bone marrow serum than in venous serum in 20 cats. Glucose concentrations in bone marrow serum from 19 cats were lower than those in venous serum. Correlation between calcium concentrations in venous and bone marrow serum was not found.