bluuebunny/crossref_metadata_2025_split huggingface dataset:
Arrhythmic variant of post-covid myocarditis: spectrum of rhythm and conduction disorders, treatment approaches
Authors: Savina P. O. , Blagova O. V. , Ainetdinova D. Kh. , Sedov A. V. , Novikova I. V. , Pavlenko E. V. , Lutokhina Yu. A. , Alexandrova S. A. 
Published: October 2023

Aim. To study the spectrum of rhythm and conduction disorders in patients with arrhythmic variant of postcovid myocarditis and determine the treatment approaches.Methods. The study included 23 patients with post-COVID-19 по абстракту разное написание. Post-COVID arrhythmias who had at least two of the three Lake-Louise criteria for myocarditis on magnetic resonance imaging of the heart and/or elevated anticardiac antibody (ACA) titers. The period of occurrence of post-COVID arrhythmias was 4.0 [2.0; 8.0] months, from 2 to 34 months. Echocardiography, Holter monitoring, and ACA study were performed. Cardiac magnetic resonance imaging was performed in 70% of patients (n=16). Coronary artery disease was excluded in 9 patients with risk factors.Results. In all patients’ arrhythmias were associated with COVID-19. Rhythm and conduction disturbances occurred within 2 to 34 months after infection. Echocardiography revealed no left ventricle systolic dysfunction. In all patients, an increase in ACA by 3 or more times was noted, in 65.2% (n=15) a specific antinuclear factor (ANF) was detected, reflecting the high immunological activity of myocarditis. Ventricular arrhythmias in most cases were represented by frequent ventricular extrasystole. Among supraventricular arrhythmias, frequent extrasystoles, non-sustained tachycardia, paroxysmal form of atrial fibrillation were detected. In one case, a transient atrioventricular block II-III degree developed. Treatment approaches included antiarrhythmic and immunosuppressive therapy. All patients underwent Holter monitoring, which showed regression of arrhythmias. Patients with high immunological activity of myocarditis underwent immunosuppressive therapy with methylprednisolone 8-16 mg/day (n=13), with moderate - mild immune-suppressive therapy with hydroxychloroquine 200 mg/day (n=10). When controlling the ACA titers, their decrease was noted. The decrease in the specific ANF titer was close to statistically significant (p=0.057). Interventional treatment of arrhythmias was performed in three patients.Conclusions. Arrhythmias that first developed after COVID-19 require the exclusion of subacute/chronic myocarditis that develops 2-8 months after COVID-19. The spectrum of arrhythmias in patients with post-COVID myocarditis is mostly represented by frequent symptomatic extrasystoles. Basic therapy of the arrhythmic variant of post-COVID myocarditis with methylprednisolone and/or hydroxychloroquine makes it possible to increase the effectiveness of antiarrhythmic drugs with the opportunity of their complete withdrawal in some patients.
A geographic-location-based medical school admissions process does not influence pre-clerkship and licensing examination academic performance
Authors: Ross Brian M , Acharya Shreedhar , Welch Meggan , Biasiol Katherine , Prowse Owen , Hogard Elaine 
Published: October 2023

Background: Students are selected for admission to the Northern Ontario School of Medicine University (NOSM U) MD degree program using criteria aiming to maximize access of persons thought most likely to practice in the region, including use of a geographic context score (GCS) which ranks those with lived experience in northern Ontario and/or rurality most highly. This study investigates the effect of this admissions process upon medical school academic performance.
Methods: We used a retrospective cohort design combined with multiple linear regression analysis to investigate the relationship between admission scores and performance on pre-clerkship courses, and the Medical Council of Canada Qualifying Exam Part 1 (MCCQE1).
The GCS did not significantly explain performance variance on any pre-clerkship course, nor on the MCCQE1, while the undergraduate Grade Point Average correlated with most assessment scores. The number of prior undergraduate biomedical courses predicted science and clinical skills performance, particularly in Year 1, but not with MCCQE1 scores. Performance on Year 2 courses, particularly foundational sciences and clinical skills, significantly predicted MCCQE1 scores.
Results: Our data suggest that admission geographic context scoring is unrelated to future academic performance. Further, students with fewer prior undergraduate biomedical courses may benefit from increased support and/or a modified program during the early years.
Jeu d'évasion médical: expérimentation d'une nouvelle méthode pédagogique
Authors: Larouche Pauline , Sweeney Kevin , Lajeunesse Judith 
Published: October 2023

Énoncé des implications de la recherche
En pédagogie médicale, nous cherchons à développer des activités d’enseignement stimulantes et davantage centrées sur l’apprenant. Nous avons donc adapté le concept d’un jeu d’évasion médical déjà existant aux besoins de nos résidents en médecine familiale en préparation à leurs examens. Cette activité présente une façon ludique d’intégrer des apprentissages théoriques, mais également de développer plusieurs compétences CanMeds. Les résidents ont été globalement très satisfaits, autant quant à l’intégration des connaissances des sujets choisis que pour l’aspect interactif de l’expérience. Cette activité nécessite peu de ressources et peut être adaptée dans différents milieux et selon les besoins des étudiants.
A Cross Sectional Study of Cephalic Index using Various Measurement Techniques in Varanasi Region of North Indian Population
Authors: Kenchok Ongmu Bhutia  , Deepa Durga Roy  , Surendra Kumar Pandey  , Ashish Verma  , Deepan Roy  
Published: October 2023

Background: Cephalic Index is defined as the ratio calculated by the occipitofrontal diameter (OFD) to thebiparietal diameter (BPD).It has been reported that factors like race, ethnicity, genetic interactions, traditions, nutrition, environment, andclimate influences head types.The multifariousness of our nation fascinates and raises the need for anthropometric studies in various regionsand compare the outcomes.The cross-sectional study was carried on three different groups/subjects of either sex.Group 1 comprised of living subjects (Undergraduate students) belonging to this particular region.Group 2 comprised of those that presented to the radio- diagnosis department of Sir Sunderlal Hospital, IMS,BHU, UP, India.Group 3 comprised of dry skulls available in the departmental museum of department of Forensic medicine, IMS,BHU, UP, India.The measurement of maximum cranial breadth and maximum cranial length, are taken manually/on DICOM CTrecords depending on the group and recorded for analysis.The average CI in both the sexes and prevalence of the type is classified according to Martin and Saller classification.(1957)Objectives: The objectives were to find out the prevalence of the type of skull in the study population. It wouldalso show the sensitivity of radiology and its efficaciousness in anthropometric measurements. To ascertain themean CI,range of maximum cranial breadth and maximum cranial length.Result: A total of 70% amongst the study population shows dolichocephalisation.The mean cephalic index in this particular study population was 73.92 ± 5.05.
Maximum cranial breadth ranged from 10.4cms to 16.2cms with a mean breadth of 13.21±0.93.Maximum cranial length ranged from 15.6 cms to 20.67cms with a mean length of 17.89 ± 0.86.Conclusion: The observations and findings of the present study based on CT can be replicated in variouscommunities, castes, and regions of India. The data can also be helpful in establishment of identity particularlyrace using skeletal remains.
Ab Initio Study of Glycine Formation in the Condensed Phase: Carbon Monoxide, Formaldimine, and Water Are Enough
Authors: Carrascoza Francisco , Lukasiak Piotr , Nowak Wieslaw , Blazewicz Jacek 
Published: October 2023

Abstract
Glycine is considered to be crucial in the formation of proteins and prebiotic substances. Nevertheless, the mechanism of spontaneous glycine formation under prebiotic Earth conditions or within the interstellar medium (ISM) remains a topic of debate, given the changing geochemical environment over Earth’s history and the difficulty of detecting it within the ISM. Yet it is believed that its formation could be possible in interstellar water-rich ice. In this study, using molecular dynamics (MD) simulations at the ab initio level of theory enhanced with modern free energy calculations, we modeled the chemical reaction between carbon monoxide, formaldimine, and water to produce glycine. We estimated under what conditions, in condensed phase at 50, 70, 100, and 300 K, glycine is formed. We also explored the effect of different electric fields on this process. Our results show that glycine could be formed with energy barriers as low as 0.5 kcal mol−1 at 50 K. We discuss whether this reaction could be a suitable candidate for explaining the mechanism of glycine formation under conditions that resemble various astrophysical environments, such as planets, exoplanets, and Earth. This study is relevant to finding a consensus among various proposals for glycine formation. Moreover, it highlights the importance of metadynamics and Car–Parrinello MD methods as tools in finding unknown complex, multistep reaction mechanism pathways, possibly important to the astronomical phenomena.
Discovery and Timing of Millisecond Pulsars with the Arecibo 327 MHz Drift-scan Survey
Authors: Lewis Evan F. , Olszanski Timothy E. E. , Deneva Julia S. , Freire Paulo C. C. , McLaughlin Maura A. , Stovall Kevin , Bagchi Manjari , Martinez Jose G. , Perera Benetge B. P. 
Published: October 2023

Abstract
We present the discovery and timing solutions of four millisecond pulsars (MSPs) discovered in the Arecibo 327 MHz Drift-Scan Pulsar Survey. Three of these pulsars are in binary systems, consisting of a redback (PSR J2055+1545), a black widow (PSR J1630+3550), and a neutron star–white dwarf binary (PSR J2116+1345). The fourth MSP, PSR J2212+2450, is isolated. We present the multiyear timing solutions as well as polarization properties across a range of radio frequencies for each pulsar. We perform a multiwavelength search for emission from these systems and find an optical counterpart for PSR J2055+1545 in Gaia DR3, as well as a gamma-ray counterpart for PSR J2116+1345 with the Fermi-LAT telescope. Despite the close colocation of PSR J2055+1545 with a Fermi source, we are unable to detect gamma-ray pulsations, likely due to the large orbital variability of the system. This work presents the first two binaries found by this survey with orbital periods shorter than a day; we expect to find more in the 40% of the survey data that have yet to be searched.
Legume-cereal intercropping as a strategy of regenerative agriculture supporting reverse of biodiversity loss - relevance of microbiome-based research
Authors: Frąc Magdalena , Panek Jacek , Gryta Agata , Oszust Karolina , Pertile Giorgia , Siegieda Dominika , Mącik Mateusz , Pylak Michał , Imran Pathan Shamina , Pietramellara Giacomo 
Published: October 2023

Adverse environmental impacts connceted with high chemicals and fertilizers use is one of the causes of biodiversity loss. Therefore, there is a need to looking for more natural and non-hazardous alternative approaches to make agriculture more sustain. The legume-cereal intercropping is currently one of the „hot topics” in the area of sustainable and regenerative agriculture. These intercropping practices are increasingly gaining attention as a way for enhancing soil ecosystem services and reversal biodiversity loss, as well as as a strategy of harnesing plant yield quality and soil health.
Legume-cereal systems are the most common intercropping combinations used in sustainable agriculture models because of their noncompeting niche requirements and atmospheric nitrogen fixation which improve a balance of this nutrient in soil and plant and decrease the amount of mineral fertilizers use. However, conventional crop rotations in the EU are largely dominated by cereals while legume cultivation has declined in recent years.
The idea of the LEGUMINOSE project includes that multi-species assemblages of plants deliver rhizosphere functions that are greater than the sum of the functions delivered by the rhizospheres of individual plants growing alone as a monoculture. We hypotheses that the higher plant diversity in intercropping will increase plant health, improve soil biodiversity and reduce the use of pesticides in agroecosystems. However ther is a knowledge gap concerning plant-soil-microbe interactions under root exudation from single and diverse plant assemblage and role of soil microbiomes in soil ecosystem functionality and plant production. Therefore we will focus on understanding these interactions by the microbiome research of soil and plant niches, including bulk soil, rhisozphere, roots and shoots of cereal and legume plants in order to assess the percentage of microbiota transfered between them within monocropping and intercropping fields and understand relationships of that microbiomes in plant health improvement. This project will design and implement sustainable environmental practices based on legume-cereal intercropping systems that account for the nature, impacting to global biogeosphere changes.
Research funded in the frame of Horizon Europe Programme, agreement no. Project 101082289 — LEGUMINOSE.
Barrières et facilitateurs de l’utilisation des services de santé de la reproduction en Côte d’Ivoire : une étude qualitative auprès de la communauté
Authors: Agbré-Yacé Marie Laurette , Kourouma Kadidiatou Raïssa , Doukouré Daouda , Ndia Félix Anon , Kpébo Denise , Koumi-Mélèdje Marie Dorothée , Yaya Bocoum Fadima , Bousso Senghor Diarra , Aké-Tano Odile 
Published: October 2023

Introduction : L’amélioration des indicateurs de santé reproductive, maternelle, néonatale, infantile et adolescente et de la nutrition (SRMNIA+N) représente un challenge pour les systèmes de santé, principalement ceux des pays d’Afrique subsaharienne. Cette étude avait pour objectif d’identifier les barrières et facilitateurs à l’utilisation des services de SRMNIA+N dans les zones à faibles indicateurs en Côte d’Ivoire. Méthodes : Une étude de cas par approche qualitative auprès de 76 bénéficiaires des services de SRMNIA+N a été menée en septembre 2021 dans les districts sanitaires de Boundiali, Toulepleu et Tanda. Des entretiens individuels et des discussions de groupe ( focus groups ) ont été organisés respectivement auprès des leaders communautaires, tradipraticiens ou matrones et des femmes enceintes ou en âge de procréer et des hommes ayant la charge d’un enfant de moins de 5 ans. Une analyse thématique a été réalisée après codage des données dans NVivo 12. Résultats : Les barrières à l’utilisation des services de SRMNIA+N étaient la non-disponibilité de certains équipements ou commodités, les soins irrespectueux dans certains services de SRMNIA+N, le manque d’autonomie financière et/ou décisionnelle des femmes et la présence de prestataires de sexe masculin. Les facilitateurs identifiés étaient : l’accessibilité géographique, l’implication des hommes dans la santé du couple mère/enfant, la sensibilisation de la population. Conclusion : L’amélioration de l’utilisation des services de SRMNIA+N nécessite la mise en œuvre d’interventions adressant ces barrières et facilitateurs tels que la sensibilisation de la communauté sur les services de SRMNIA+N, la promotion auprès des prestataires de santé des soins humanisés respectueux et centrés sur le patient.
Mesure de la charge virale VIH : connaissances, attitudes et pratiques des agents de santé, Burkina Faso
Authors: Ouédraogo Smaïla , Dahourou Désiré Lucien , Diallo Ismaël , Sarigda Maurice , Romba Issa , Yonli Bapougouni Philippe Christian , Dah Ter Elias , Kaboré Ahmed , Méda Nicolas 
Published: October 2023

Introduction : Environ un quart des personnes vivant avec le virus de l’immunodéficience humaine (PVVIH) avait réalisé une charge virale plasmatique (CVP) en 2020 au Burkina Faso. Le but de cette étude était d’évaluer les connaissances, les attitudes et les pratiques (CAP) des agents de santé en matière de mesure de la CVP du VIH. Méthodes : Une étude transversale a été conduite auprès des agents de santé impliqués dans la prise en charge des PVVIH dans les 13 régions du Burkina Faso en 2021. Des scores ont été construits pour évaluer leurs CAP sur la mesure de la CVP. Les facteurs associés aux connaissances et pratiques ont été identifiés par une régression logistique. Résultats : Au total, 255 agents de santé ont été inclus dans l’étude. La majorité avait de bonnes connaissances (73 %) et des attitudes favorables (93 %). Cependant, 40 % avaient des pratiques inadéquates. Tenant compte de la disponibilité d’un laboratoire de réalisation de la CVP au sein du centre de santé, occuper un rôle de coordonnateur augmentait la probabilité d’avoir de bonnes connaissances, tandis que ne pas avoir une qualification médicale réduisait cette probabilité. Les bonnes pratiques étaient plus courantes chez les agents santé travaillant au deuxième niveau de la pyramide sanitaire. Conclusions : Des interventions pour accroître la réalisation de la CVP sont indispensables pour améliorer la prise en charge des PVVIH. Par exemple, des investigations futures pourraient étudier le rôle des médiateurs dans l’accroissement de la demande de la CVP auprès des PVIHH et de leur soignant.
Los indicios auríferos sobre la Fm Vegadeo en el corredor Navelgas-Trevías (Zona Asturoccidental-Leonesa)
Authors: González Nistal Santiago , Ordóñez Alonso Almudena , García Ordiales Efrén , Alberquilla Martínez Fernando , Alvarez García Rodrigo 
Published: October 2023

En este trabajo se presentan algunos resultados de interés práctico sobre las mineralizaciones de oro que aparecen en el sector norte del cinturón aurífero de Navelgas (Zona Asturoccidental-Leonesa). El indicio de Navelgas, el más importante del área de estudio, presenta una mineralización hidrotermal cuya paragénesis se ha completado con la presencia de arsenopirita, lollingita, Bi nativo, bismutinita, gersdorfita, violarita, monacita y parisita. El oro nativo, escaso, se asocia a pirita y asenopirita. La primera, mayoritaria, contiene 625 mg·kg-1 de oro refractario invisible. El microanálisis de elementos traza en oro aluvionar indica que en la cuenca alta del río Navelgas existen varios indicios, no conocidos, de oro primario, probablemente asociados a filones de cuarzo.
En el área de San Feliz, unos 12 km al NE de Navelgas, se ha identificado la presencia de oro refractario (727 mg·kg-1) en la goethita (pseudomorfa de pirita) de los eluviones que se desarrollan sobre la Fm Vegadeo, lo que parece indicar la posible existencia de zonas profundas mineralizadas.
En el área de San Feliz, unos 12 km al NE de Navelgas, se ha identificado la presencia de oro refractario (727 mg·kg-1) en la goethita (pseudomorfa de pirita) de los eluviones que se desarrollan sobre la Fm Vegadeo, lo que parece indicar la posible existencia de zonas profundas mineralizadas.
Le prix de l’eau à Bruxelles ne respecte pas le principe du pollueur-payeur
Authors: May Xavier 
Published: October 2023

L’ordonnance Cadre Eau impose le cout-vérité de l’eau conformément au principe du pollueur-payeur. En pratique, les consommateurs d’eau – domestiques et non domestiques – bruxellois sont les principaux contributeurs au financement de la lutte contre les inondations, de la collecte et de l’épuration des eaux présentes dans le réseau unitaire d’égouts bruxellois. Cependant, environ la moitié des eaux résiduaires sont des eaux de pluie et des eaux claires parasites qui ne sont pas liées à la consommation d’eau. Les consommateurs ne devraient donc pas être mis à contribution pour les couts qu’elles engendrent en vertu du principe du pollueur-payeur. Nous estimons que 20 % de la facture d’eau des consommateurs est indument à leur charge et examinons comment ces montants pourraient être financés autrement.
Application of Embedded Digital Twin to Increase the Fault-Tolerance of Electric Subsea Valve Actuators
Authors: Duarte da Silva Joao Pedro , Alexandre Orth , Markus Kubacki , Prudente da Silva Guilherme , Juliano De Negri Victor 
Published: October 2023

Abstract
The digitalization of production and processing systems has significant potential to greatly benefit the Oil & Gas industry, as well as for Carbon Capture Utilization and Storage (CCUS) and for green hydrogen (H2) production using offshore renewable energy. Digital Twins, in particular, play a critical role in not only designing new applications but also enhancing existing machinery. This integration of advanced technologies empowers the industry to achieve unprecedented levels of efficiency, controllability, and predictive maintenance, ensuring a more competitive and sustainable future.
This paper focuses on developing an embedded Digital Twin for an electric subsea valve actuator, which was modeled using state-space equations based on its physical counterpart's components. Its state-space matrices are continually updated through controller output signals and recalculating system parameters, including mechanical and volumetric efficiencies and the production valve signature, based on data from sensors. To achieve continuous updates, an online and recursive system identification technique employing a Kalman Filter is used to update the Digital Twin's parameters.
Throughout the experiment, a MATLAB script subjected the Digital Twin model to tests utilizing data from the physical counterpart. Both scenarios, with and without online and recursive parameter identification, were explored. Remarkably, the Digital Twin adeptly adapted its parameters, mirroring the behavior of its physical counterpart. The findings conclusively exhibited that the embedded Digital Twin enables condition monitoring of the physical counterpart, bridging sensor gaps and compensating for sensor faults. Such proactive maintenance capabilities enhance equipment reliability significantly. This feature is used in this study to increase the fault-tolerance of an electric Subsea Valve Actuator, providing a digital redundancy to critical components such as position and torque sensors.