bluuebunny/crossref_metadata_2025_split huggingface dataset:
CULTIVATING CRITICAL THINKING IN PRACTICAL CLASSES DURING PATHOMORPHOLOGY AS AN INTEGRAL PART OF THE EDUCATIONAL PROCESS
Authors: Garvasiuk O.V. , Ilika V.V. , Guz L.O. , Kulachek V.T. , Malaiko S.S. 
Published: December 2023

The aim of this study is to explore and suggest methods for cultivating critical thinking in medical students during practical classes at a higher education institution.
Results and discussion. Critical thinking is recognised as skilled thinking that makes good judgements because it is criterion-based, self-improving and context-sensitive. The process of developing critical thinking has the ultimate goal of teaching how to solve situational problems, persevere in solving problems, have flexible communication skills in teamwork, learn to listen to the interlocutor, be able to consider problems from different perspectives and consider multiple connections between phenomena, build logical conclusions, reflect on their feelings and thoughts, set goals and achieve goals. Thus, cultivating critical thinking in practical classes over the course of Pathomorphology is an integral part of the educational process.
Considering the role that Pathomorphology plays as a bridge between theoretical and clinical disciplines, the faculty of departments teaching this subject confronts the challenge of fostering critical thinking in medical students. This article is dedicated to exploring various methods for developing critical thinking in medical students within higher education institutions. The following methods are considered: development of critical thinking through reading and writing, cluster, Fishbone method, question cube, Daisy of Questions, syncreate, Lotus Flower and Tree of Predictions (Decisions). It is extremely important to introduce training to foster critical thinking (solving real problems and making decisions by students in various situations); to create reasonable grounds for choosing the most appropriate methods, techniques, forms and means of teaching. The considered methods of forming critical thinking in medical students have effectively proved themselves in practical classes in pathomorphology at the higher education institution "Bukovinian State Medical University". In the future, there is a need to study other methods of critical thinking, such as "six hats of thinking", essay, etc.
Conclusion. Cultivating critical thinking in medical students stands as one of the paramount responsibilities for the teaching staff in any higher education medical institution. Critical thinking is the skill of analyzing and making well-considered decisions independently. It represents a distinct form of thinking marked by activity, purposefulness, independence, discipline, and reflection
POTENTIAL FOR PATHOGENETIC CORRECTION OF PROTEASE-ANTIPROTEASE SYSTEM IMBALANCE IN PATIENTS WITH COMORBIDITY OF STABLE ANGINA PECTORIS OF THE II-III FUNCTIONAL CLASS AND STAGE II-III CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Authors: Dotsenko S. Ya. , Kraidashenko О. О. 
Published: December 2023

The aim of this study is to assess the clinical effectiveness of the therapy including exogenous L-arginine and statins under the comorbidity of stable angina pectoris of the II-III functional class and chronic obstructive pulmonary disease of the II-III stage.
Materials and methods. The study included 50 patients with coronary heart disease and chronic obstructive pulmonary disease (mean age 57 years; male/female ratio 78/22%). In order to assess the clinical effectiveness of the therapy for combined cardiopulmonary pathology, the patients were randomized into 2 subgroups: subgroup 1 included 25 patients who took metabolitotropic medication under high-intensity statin therapy (the basic therapy included L-arginine and rosuvastatin as a hypolipidemic agent in a dose of 20 mg/day); subgroup 2 included 25 patients who received only basic therapy under moderately intensive statin therapy (daily doses of atorvastatin 20 mg, rosuvastatin 10 mg)). The groups were comparable in terms of gender distribution and demographic characteristics. Comparative analysis of smoking experience, initial smoking age and smoking history did not differ significantly between the groups. After 12±1 weeks, a control examination was carried out.
Results. The analysis of the ratio of the MMP-9 activity level before and after the therapy showed that the level of MMP-9 expression decreased by 43.28% (p<0.05) in the 1st subgroup and by 13.18% in the 2nd subgroup until the end of the therapy. TIMP activity after 12 weeks of the treatment was +33.11% (p<0.05) and +11.27% for the 1st and 2nd subgroups respectively. The difference between subgroups 1 and 2 in the level of the CRP marker before and after the therapy was -45.65% (p<0.05) and -9.09%, respectively. 76% of people from the 1st subgroup reached the target level of healthy people before the completion of the therapy that is significantly higher than the similar indicator in the 2nd subgroup (32%) at χ2=8.05, p<0.01.
Conclusions: The application of L-arginine alongside high-intensity statin therapy for patients presenting with stable angina pectoris of the II-III functional class and stage II-III chronic obstructive pulmonary disease (COPD) resulted in more notable positive changes in the modulation of protease-antiprotease status disorders. This was evidenced by a reduction in the heightened expression of MMP-9 and an increase in the level of TIMP during the course of treatment.
Analisis Kekerasan Papan Komposit dari Serat Pelepah Pisang Dengan Resin Polyester
Authors: Lelawati  , Tonadi Een , Aan Sefentry  
Published: December 2023

Tanaman Pisang banyak tumbuh di bagian dataran rendah dengan ketinggian 100 meter di atas permukaan laut, jenis tanah yang lembab dan berada pada wilayah terbuka. Bahan komposit adalah material rekayasa yang tersusun dari dua atau lebih bahan utama yang dikombinasikan guna mendapatkan sifat mekanis (mechanical properties) yang lebih baik. Tujuan dari penelitian ini adalah untuk mengetahui nilai kekerasan material komposit dari bahan serat pelepah pisang dengan variasi resin dan jenis serat. Metode pengujian kekerasan menggunakan metode Rokcwell dengan 5 titik pengujian pada masing-masing spesimen. Spesimen terdiri dari 3 variasi yaitu papan komposit tanpa serat dengan resin 90% dan katalis 10%, serat pelepah pisang Panjang 95 mm sebanyak 70%, resin 20% dan katalis 10%, serbuk pelepah pisang 80%, resin 10% dan katalis 10%. Hasil penelitian ini spesimen dengan komposisi resin 90%, katalis 10% didapat nilai kekerasan rata-rata 97,8 HRC. Spesimen dengan panjang serat 95 mm dengan komposis 70%, resin 20%, katalis 10% didapat nilai kekerasan rata-rata 105,9 HRC Spesimen menggunakan serbuk pelepah pisang 80%, resin 10%, katalis 10% didapat nilai kekerasan 90,7 HRC. Kesimpulannya spesimen dengan perbandingan panjang serat 95 mm 70%, resin 20%, katalis 10% mempunyai nilai kekerasan yang paling tinggi dibandingkan dengan spesimen tanpa serat, dan perbandingan serbuk pelepah pisang 80%, resin 10%, katalis 10%.
Library Science and Library Sphere in Conditions of Martial Law in Ukraine
Authors: Klymenko Oksana , Sokur Olena 
Published: December 2023

The aim of the article is to research main tendencies in the development of scientific studies and priority directions of library practice in conditions of martial law in Ukraine, using the example of publications in the journal “Bibliotechnyi visnyk” (“Library Bulletin”).
Research methods. The article embraces a complex of approaches of scientific knowledge (objectivity, connection between theory and practice); the principle of unity and interconnection with current conditions; cognitive, structural-functional, descriptive and source studies methods, as well as analysis and synthesis.
Scientific novelty. For the first time, the content of the scientific-theoretical and practical journal “Bibliotechnyi visnyk” (2022–2023) is presented as an integral component of the progress of Ukrainian library science, and as a basis of functioning the state’s library sphere. It is argued that in conditions of martial law in Ukraine, library science and library sphere have been developing according to all-Ukrainian tendencies.
Main conclusions. The use of modern information and communication technologies in the publishing activity of V. I. Vernadsky National Library of Ukraine, as the founder and publisher of the scientific-theoretical and practical journal “Bibliotechnyi visnyk”, in conditions of martial law in Ukraine, has contributed to the apropos initiation of the library community and the world (the mentioned above journal is distributed to 25 countries by international book exchange), with the main development trends of scientific studies and modern areas of library practice in Ukraine and abroad. In 2022–2023, the themes of publications in “Bibliotechnyi visnyk” journal are determined by diversity and topicality, as they reveal the main directions, represent the leading main tendencies in the development of library science and library sphere in Ukraine and abroad, as well as demonstrate the growing role of libraries in the digital era. In conditions of martial law in Ukraine, publications on the mentioned topics, including the experience of foreign libraries, have become relevant.
KESULITAN BELAJAR MATA KULIAH BAHASA INDONESIA PADA MAHASISWA SEKOLAH TINGGI AGAMA KATOLIK NEGERI PONTIANAK
Authors: Kurniati Yusi , Romadani Anggit Tiyas Fitra 
Published: December 2023

ABSTRAKPenelitian ini bertujuan untuk mendeskripsikan kesulitan belajar mata kuliah Bahasa Indonesia pada mahasiswa STAKat Negeri Pontianak dan mendeskripsikan faktor penyebab kesulitan belajar mahasiswa. Penelitian ini merupakan penelitian deskriptif kualitatif. Hasil penelitian menunjukkan bahwa materi perkuliahan Bahasa Indonesia yang paling sulit dipahami oleh mahasiswa adalah materi tentang Menyusun Daftar Pustaka, Menulis Kutipan, dan Diksi. Kesulitan belajar tersebut disebabkan oleh berbagai faktor antara lain motivasi dan minat mahasiswa, kompetensi dosen, kompetensi mahasiswa, serta lingkungan dan sarana prasarana. Namun, dari berbagai faktor penyebab tersebut, faktor yang paling dominan adalah faktor kompetensi mahasiswa sebab masih banyak mahasiswa yang tidak aktif dalam perkuliahan yang disebabkan oleh tidak berani untuk berpendapat.Kata Kunci: kesulitan belajar, Mahasiswa, Bahasa Indonesia.ABSTRACTThis research aims to describe the difficulties in learning Indonesian language courses among STAKat Negeri Pontianak students and describe the causes of students' learning difficulties. This research is a qualitative descriptive study. The results of the research show that the Indonesian language lecture material that is most difficult for students to understand is the material on Compiling a Bibliography, Writing Quotes, and Diction. The lack of smooth learning is caused by various factors, including student motivation and interest, lecturer competence, student competence, as well as the environment and infrastructure. However, of the various causal factors, the most dominant factor is the student competency factor because there are still many students who are not active in lectures because they do not dare to express their opinion.Keywords: learning difficulties, students, Indonesian.
PENERAPAN MODEL DISCOVERY LEARNING DALAM UPAYA MENINGKATKAN HASIL BELAJAR PENDIDIKAN AGAMA KATOLIK
Authors: Imen Bonifasius 
Published: December 2023

ABSTRAKKurangnya daya serap peserta didik, keterbatasan sarana dan prasarana sekolah serta variasi guru dalam pembelajaran berdampak pada rendahnya hasil belajar peserta didik. Penelitian ini bertujuan untuk menganalisis penerapan model Discovery Learning terhadap peningkatan hasil belajar mata pelajaran PAK-BP dengan materi Gereja Sebagai Komunitas Orang Beriman. Penelitian ini adalah Penelitian Tindakan Kelas (PTK). Subjek penelitian adalah peserta didik kelas VIII sebanyak 12 orang dengan objek penelitian hasil belajar peserta didik mata pelajaran PAK-BP. Pengumpulan data dilakukan dengan teknik observasi, angket dan tes. Analisis data dilakukan dengan pendekatan kuantitatif dan kualitatif. Hasil penelitian menunjukkan bahwa adanya peningkatan hasil belajar peserta didik, yaitu pada siklus I sebesar 56% (kognitif sebesar 41,67%, Afektif sebesar 67,17% dan Psikomotor sebesar 59,17%) dengan sebaran 12 peserta didik pada kategori “Layak” meningkat di siklus II sebesar 76,91% (kognitif sebesar 72,33%, afektif sebesar 79,58% dan Psikomotor sebesar 73,61%) dengan sebaran 2 peserta didik pada kategori “Mahir”, 8 peserta didik pada kategori “Cakap” dan 2 peserta didik pada kategori “Layak”. Hal in berarti terjadi peningkatan hasil belajar sebesar 20,91%. Dapat disimpulkan bahwa penggunaan model Discovery Learning pada mata pelajaran PAK-BP dapat meningkatkan hasil belajar peserta didik.Kata Kunci: Hasil belajar, Discovery Learning, Pendidikan Agama Katolik dan Budi PekertiABSTRACTThe lack of student absorption capacity, limited school facilities and infrastructure and the lack of teacher variation in learning have an impact on low student learning outcomes. This study aims to analyze the application of the Discovery Learning model to improve learning outcomes in PAK-BP subjects with material on the Church as a Community of Believers. This research is Classroom Action Research (CAR). The research subjects were 12 class VIII students with the research object being the learning outcomes of students in the PAK-BP subjects. Data collection was carried out using observation techniques, questionnaires and tests. Data analysis was carried out using quantitative and qualitative approaches. The results of the research showed that there was an increase in student learning outcomes, is 56% in cycle I (cognitive by 41.67%, affective by 67.17% and psychomotor by 59.17%) with a distribution of 12 students in the "Decent" category. increased in cycle II by 76.91% (cognitive by 72.33%, affective by 79.58% and psychomotor by 73,61%) with a distribution of 2 students in the "Proficient" category, 8 students in the "Competent" category and 2 students in the "Decent" category. This means that there has been an increase in learning outcomes by 20.91%. It can be concluded that the use of the Discovery Learning model in PAK-BP subjects can improve student learning outcomes.Keywords: Learning outcomes, Discovery Learning, Catholic Religious Education and Character
Pengaruh Pelatihan Terhadap Kinerja Melalui Motivasi Pada Karyawan PT PLN Unit Pelaksana Pengendalian Pembangkitan Tello
Authors: Khaira Fastabiqul , Syamsuddin Syamsuddin 
Published: December 2023

This research aimed to determine the effect of training on performance through motivation among employees of PT PLN Unit Pelaksana Pengendalian Pembangkitan Tello. The research used an associative research design. The sampling technique used was proportionate sampling with a total of 70 employees. Data analysis included tests for instrument validity and reliability, classica assumption tests, descriptive data analysis, inferential data analysis using T-test and F-testco efficient of determination analysis, path analysis, and Sobel test. The data was processed using SPSS for Windows version 25.0.Based on the research conducted by the researcher at PT PLN Unit Pelaksana Pengendalian Pembangkitan Tello, it was found that the training, performance, and employee motivation were excellent. The training significantly influenced performance, and it also had a significant effect on employee work motivation. Employee motivation had a significant effect on performance. The indirect effect of training on performance through motivation was smaller than the direct effect of training on employee performance, indicating that motivation mediated the relationship between training and performance improvement.
Peran Dukungan Keluarga dalam Melakukan Pemeriksaan Payudara Klinis pada Wanita
Authors: Laili Fitria Jannatul , Claudia Jessica , Nisa Khoirun 
Published: December 2023

Banyak klien (Wanita Usia Subur/WUS) enggan untuk melakukan pemeriksaan payudara klinis (SADARNIS). Klien merasa malu dan khawatir jika ditemukan penyakit atau didiagnosis mengalami penyakit tertentu. Ada beberapa WUS yang berpikir bahwa dirinya tidak merasakan keluhan pada Payudaranya sehingga merasa tidak memerlukan pemeriksaan payudara secara rutin. Padahal deteksi awal pencegahan terjadinya kesakitan dan kematian karena kanker payudara sangat penting. Kanker payudara dapat dideteksi secara diri dengan dilakukannya pemeriksaan payudara sendiri (SADARI) dan SADARNIS secara rutin. Jika seorang wanita mengalami kanker payudara yang sebelumnya tidak melakukan SADARNIS ataupun SADARI secara rutin maka kemungkinan besar datang ke fasilitas kesehatan dalam kondisi sudah parah. Oleh karenanya, perlu dukungan kepada para wanita untuk percaya diri sehingga mau melakukan SADARNIS secara rutin. Dukungan ini terutama oleh suami dan/ atau keluarga. Peran suami atau keluarga telah terbukti efektif dalam memberikan kesempatan kepada para wanita untuk SADARNIS secara rutin.

Kata Kunci: Peran Dukungan Keluarga, Pemeriksaan Payudara Klinis
Safety evaluation of high bioavailability curcumin in Healthy Japanese Adults: A Randomized, placebo-controlled, double-blind, parallel-group comparison study
Authors: Lee Hyunjin , Kuwabara Yoshitaka , Hirose Akiko , Kakinuma Toshihiro , Baba Asami , Takara Tsuyoshi 
Published: December 2023

Background: Curcumin is the principal component responsible for the pharmacological action of Curcuma longa. It has been proven to exhibit a diverse range of functions. It has been used in many fields as a spice, coloring agent, cosmetic, and food preservative.Objective: To evaluate the safety of the intake of highly bioavailable curcumin (CR-033P and TS-P1) in humans. Methods: We conducted two trials. The participants were healthy Japanese adults. Participants of tria1 1 (Long-term intake trial) took CR-033P or TS-P1 for 12 weeks (as curcumin 150 mg/day). Participants of Trial 2 (Excessive intake trial) took TS-P1 for 4 weeks (as curcumin 750 mg/day). The safety assessment involved monitoring the occurrence of side effects or adverse events, along with the analysis of urinalysis and blood parameters.Results: The safety analysis population of Trial 1 included 33 participants in the CR-033P group, 32 participants TS-P1, and 30 participants in the Placebo group. The safety analysis population of trial 2 included 22 participants in TS-P1 and 20 participants in the Placebo group. In both Trial 1 and Trial 2, few participants were observed to experience adverse events and however these were not adverse events related to the CR-033P or TS-P1. Results of urinalysis and blood analysis were confirmed to not exhibit medically problematic changes related to the CR-033P or TS-P1.Conclusions: These trials proved the safety of the long-term intake of CR-033P or TS-PI- (as curcumin 150mg/ day) and the safety of the excessive intake of TS- P1 for four weeks (as curcumin 750mg/ day). TS-P1 and CR-033P can be considered a safe curcumin supplement based on these results. Keywords: Curcumin, bioavailability, safety, high dose, long term dose, Healthy Japanese Adults, BMI, Blood pressure Trial registration: Trial 1: UMIN000046160, Trial 2: UMIN000048797. Foundation:Theravalues Corporation
Prognostic significance of albumin-to-alkaline phosphatase ratio for overall survival in metastatic lung adenocarcinoma patients
Authors: ÖZTÜRK ERGÜR Figen , ÖZTÜRK Ayperi , UZEL ŞENER Melahat , KURT Hasret Gizem , ÖZDAĞ Özlem 
Published: December 2023

Aims: This study aims to determine the prognostic significance of the pretreatment albumin/alkaline phosphatase ratio (AAPR) for overall survival in patients diagnosed with metastatic lung adenocarcinoma (MLA).
Methods: The medical records of 459 patients diagnosed with MLA between 2010 and 2021 were retrospectively reviewed. The AAPR was calculated using blood test results obtained at the time of diagnosis.
Results: The study identified the optimal threshold value for AAPR as 0.314. Patients with a high AAPR (AAPR>0.314) demonstrated significantly longer median survival and overall survival time compared to those with a low AAPR (AAPR ≤ 0.314) (p
The psychosocial status of siblings and mothers of children with cancer from the perspective of mothers
Authors: İLTER BAHADUR Evin , KARAHAN Feryal , ÖZDEMİR Asena Ayça 
Published: December 2023

Aims: In the low/middle income countries (LMIC), a few of health centers provide psychological support to siblings and mothers of children with cancer. The aim of study was to draw attention to psychosocial status of siblings and mothers of children with cancer in a LMIC.
Methods: The study was a case-control study which was conducted at a tertiary center in Mersin, Turkey. The sample consisted of two groups as follows; siblings of children with cancer (n=39) were included as study group and children without cancer diagnosis in family (n=49) were included as control group. Behavioral problems of the children were evaluated with the Child Behavior Checklist 4-18. Beck Depression Inventory (BDI) and Multidimensional Perceived Social Support Scale (MSPSS) were used for maternal depressive symptoms and maternal perceived social support.
Results: In contrast to what was expected, there was no statistical difference in behavioral problems among two groups. Maternal BDI was higher and MSPSS was lower in the study group compared to the control group. Study group had more school difficulties such as absenteeism (p
Pathogen distribution and microbial resistance pattern in endotracheal aspirate samples of intensive care unit patients before and after the COVID-19 pandemic
Authors: DURAN Hülya , KİRAZ Nuri , UTKULU Zülal Zeynep , ERDAL Berna , UYAR Yavuz 
Published: December 2023

Aims: The aim of this study is to evaluate the distribution of pathogen microorganisms and antimicrobial resistance rates isolated from endotracheal aspirate (ETA) samples of SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) polymerase chain reaction (PCR) positive and negative patients followed and treated in the intensive care unit (ICU) of our hospital, and to examine the effect of the COVID-19 (coronavirus disease 2019) pandemic on this.
Methods: In this study, ETA samples sent to the microbiology laboratory from hospitalized patients in Tekirdağ Namık Kemal University Hospital general ICU-1 and general ICU-2 between March 11, 2018 and March 10, 2022 were retrospectively analyzed. During the COVID-19 pandemic, it was used to follow up patients with SARS-CoV-2 PCR positive in ICU-1 and SARS-CoV-2 PCR negative patients in ICU-2. The working period is divided into two parts as pre-pandemic (2018 - 2019) and post-pandemic (2020 - 2021). Bacterial identification and antibiotic susceptibility tests were performed using conventional methods and automated systems. Colistin sensitivity was studied by broth microdilution, and ceftazidime avibactam (CZA) sensitivity was studied by disk diffusion method. Statistical analysis was performed with the chi-square test, p