bluuebunny/crossref_metadata_2025_split huggingface dataset:
Household Health-Related Social Needs in Newborns and Infant Behavioral Functioning at 6 Months
Authors: Anyigbo Chidiogo , Liu Chunyan , Ehrlich Shelley , Reyner Allison , Ammerman Robert T. , Kahn Robert S. 
Published: December 2023

ImportanceDysfunctional patterns of behavior during infancy can predict the emergence of mental health disorders later in childhood. The Baby Pediatric Symptom Checklist (BPSC) can identify indicators of behavioral disorders among children aged 0 to 18 months. Understanding the association of early health-related social needs (HRSNs) with poor infant behavioral functioning can inform interventions to promote early childhood mental well-being.ObjectiveTo examine the association between household HRSNs in the first 4 months of life and BPSC results at 6 months.Design, Setting, and ParticipantsThis was a retrospective cohort analysis of longitudinal electronic health record data. Covariates were selected based on the biopsychosocial ecological model. Logistic regression analyses examined the association of HRSN domains and the number of HRSNs with the 6-month BPSC outcomes. Participants were recruited from 6 primary care clinics within 1 health system. Children aged 5 to 8 months who were evaluated for 6-month well-child visits between March 30, 2021, and June 30, 2022, were included in the study.ExposureResponses to the first HRSN screening tool that a caregiver completed for infants between 0 and 4 months of age. HRSN domains were examined individually and as the number of positive HRSNs.Main Outcome and MeasuresBPSC screen identified for clinical review due to 1 or more elevated subscales (inflexibility, irritability, and difficulty with routines) at 6 months.ResultsA total of 1541 children (mean [SD] age, 6.1 [0.5] months; 775 female [50.3%]) were included in the study. A total of 405 children (26.3%) had a BPSC screen identified for clinical review, and 328 caregivers (21.3%) reported at least 1 HRSN. Food insecurity (174 [11.3%]) and benefits issues (169 [11.0%]) were the most frequently reported HRSN. Children in households with food insecurity had statistically significant higher odds of inflexibility (adjusted odds ratio [aOR], 1.73; 95% CI, 1.14-2.63), difficulty with routines (aOR, 1.64; 95% CI, 1.05-2.57), and irritability (aOR, 1.86; 95% CI, 1.13-3.08) than children in households without food insecurity. Children in households with benefits issues had statistically significant higher odds of difficulty with routines (aOR, 1.70; 95% CI, 1.10-2.65) and irritability (aOR, 1.70; 95% CI, 1.03-2.82). Children in households with 2 or more HRSNs had consistently higher odds of having a BPSC screen identified for clinical review (aOR, 2.16; 95% CI, 1.38-3.39) compared with children with no HRSNs.Conclusions and RelevanceResults of this cohort study suggest that household food insecurity, benefits issues, and the number of HRSNs were significantly associated with a BPSC screen identified for clinical review at 6 months of age. These findings highlight the urgency of intervening on HRSNs in the newborn period to prevent adverse infant behavioral outcomes.
A new predictive parameter for dose‐volume metrics in intensity‐modulated radiation therapy planning for prostate cancer: Initial phantom study
Authors: Saito Yuki , Suzuki Ryusuke , Miyamoto Naoki , Sutherland Kenneth Lee , Kanehira Takahiro , Tamura Masaya , Mori Takashi , Nishioka Kentaro , Hashimoto Takayuki , Aoyama Hidefumi 
Published: December 2023

AbstractBackgroundOrgan‐at‐risk (OAR) sparing is often assessed using an overlap volume‐based parameter, defined as the ratio of the volume of OAR that overlaps the planning target volume (PTV) to the whole OAR volume. However, this conventional overlap‐based predictive parameter (COPP) does not consider the volume relationship between the PTV and OAR.PurposeWe propose a new overlap‐based predictive parameter that consider the PTV volume. The effectiveness of proposed overlap‐based predictive parameter (POPP) is evaluated compared with COPP.MethodsWe defined as POPP = (overlap volume between OAR and PTV/OAR volume) × (PTV volume/OAR volume). We generated intensity modulated radiation therapy (IMRT) based on step and shoot technique, and volumetric modulated arc therapy (VMAT) plans with the Auto‐Planning module of Pinnacle3 treatment planning system (v14.0, Philips Medical Systems, Fitchburg, WI) using the American Association of Physicists in Medicine Task Group (TG119) prostate phantom. The relationship between the position and size of the prostate phantom was systematically modified to simulate various geometric arrangements. The correlation between overlap‐based predictive parameters (COPP and POPP) and dose‐volume metrics (mean dose, V70Gy, V60Gy, and V37.5 Gy for rectum and bladder) was investigated using linear regression analysis.ResultsOur results indicated POPP was better than COPP in predicting intermediate‐dose metrics. The bladder results showed a trend similar to that of the rectum. The correlation coefficient of POPP was significantly greater than that of COPP in < 62 Gy (82% of the prescribed dose) region for IMRT and in < 55 Gy (73% of the prescribed dose) region for VMAT regarding the rectum (p < 0.05).ConclusionsPOPP is superior to COPP for creating predictive models at an intermediate‐dose level. Because rectal bleeding and bladder toxicity can be associated with intermediate‐doses as well as high‐doses, it is important to predict dose‐volume metrics for various dose levels. POPP is a useful parameter for predicting dose‐volume metrics and assisting the generation of treatment plans.
Tailored Design of a Water‐Based Nanoreactor Technology for Producing Processable Sub‐40 Nm 3D COF Nanoparticles at Atmospheric Conditions
Authors: Llauradó‐Capdevila Gemma , Veciana Andrea , Guarducci Maria Aurora , Mayoral Alvaro , Pons Ramon , Hertle Lukas , Ye Hao , Mao Minmin , Sevim Semih , Rodríguez‐San‐Miguel David , Sorrenti Alessandro , Jang Bumjin , Wang Zuobin , Chen Xiang‐Zhong , Nelson Bradley J. , Matheu Roc , Franco Carlos , Pané Salvador , Puigmartí‐Luis Josep 
Published: December 2023

AbstractCovalent organic frameworks (COFs) are crystalline materials with intrinsic porosity that offer a wide range of potential applications spanning diverse fields. Yet, the main goal in the COF research area is to achieve the most stable thermodynamic product while simultaneously targeting the desired size and structure crucial for enabling specific functions. While significant progress is made in the synthesis and processing of 2D COFs, the development of processable 3D COF nanocrystals remains challenging. Here, a water‐based nanoreactor technology for producing processable sub‐40 nm 3D COF nanoparticles at ambient conditions is presented. Significantly, this technology not only improves the processability of the synthesized 3D COF, but also unveils exciting possibilities for their utilization in previously unexplored domains, such as nano/microrobotics and biomedicine, which are limited by larger crystallites.
Piezoelectric Interlayer Enabling a Rechargeable Quasisolid‐State Sodium Battery at 0 °C
Authors: Ni Qing , Ding Yu , Wang Chengzhi , Bai Shiyin , Zhu Kunkun , Zhao Yongjie , Chen Lai , Li Ning , Li Jingbo , Su Yuefeng , Jin Haibo 
Published: December 2023

AbstractSolid‐state sodium (Na) batteries (SSNBs) hold great promise but suffer from several major issues, such as high interfacial resistance at the solid electrolyte/electrode interface and Na metal dendrite growth. To address these issues, a piezoelectric interlayer design for an Na3Zr2Si2PO12 (NZSP) solid electrolyte is proposed herein. Two typical piezoelectric films, AlN and ZnO, coated onto NZSP function as interlayers designed to generate a local stress‐induced field for alleviating interfacial charge aggregation coupling stress concentration and promoting uniform Na plating. The results reveal that the interlayer (ZnO) with matched modulus, high Na‐adhesion, and sufficient piezoelectricity can provide a favorable interphase. Low interfacial resistances of 91 and 239 Ω cm2 are achieved for the ZnO layer at 30 and 0 °C, respectively, which are notably lower than those for bare NZSP. Moreover, steady Na plating/stripping cycles are rendered over 850 and 4900 h at 0 and 30 °C, respectively. The superior anodic performance is further manifested in an Na2MnFe(CN)6‐based full cell which delivers discharge capacities of 125 mA h g−1 over 1600 cycles at 30 °C and 90 mA h g−1 over 500 cycles at 0 °C. A new interlayer‐design insight is clearly demonstrated for SSNBs breaking low‐temperature limits.
L‐Cysteine‐Encapsulated MXene Nanosheet Possessing Ultra‐Antioxidation in Aqueous Suspension for Electrophoretic Deposition Assisted Carbon‐Fiber‐Surface Modification
Authors: Huang Ling , Du Zheyuan , Tian Yanhong , Sun Jiangman , Li Jinglong , Xing Yue , Liang Xiubing , Zhang Xuejun 
Published: December 2023

AbstractWith recent progress in 2D materials, Ti3C2Tx MXene featured high metallic electrical conductivity, high electromagnetic interference shielding effectiveness, and super in‐plane stiffness, exhibits unique advantages in many fields, but is rarely applied as a sizing agent in long‐time continuous processing of carbon fiber sizing because of its poor ambient stability in aqueous suspension. Herein, a new strategy to chemically encapsulate the reactive sites of MXene nanosheet with l‐cysteine for restricting the attacking of water and/or oxygen in aqueous suspension is proposed. Based on the ultra‐antioxidation, polarity, and electrical properties of l‐cysteine‐encapsulated Ti3C2Tx MXene (LC‐MX) nanosheet, the LC‐MX, even if aging for weeks in aqueous suspension, can be deposited on the surface of high‐modulus carbon fiber (HMCF) uniformly via the electrophoretic deposition assisted sizing. Benefiting from the enhanced surface energy, wettability, and roughness of LC‐MX‐sized HMCF (HMCF‐LCMX) relative to that of unsized one (U‐HMCF), the interfacial property of HMCF‐LCMX/epoxy (EP) composites is also improved, for which the interlayer shear strength (ILSS) of the composite reached 88.5 MPa, 52.8% higher than that of U‐HMCF/EP composite (57.9 MPa). This work makes an essential step toward the application of ultra‐stable MXene nanosheet suspension in large‐scale continuous carbon fiber sizing.
A TiC@TiO2‐C Support for Pt Catalysts to Boost the Oxygen Reduction Reaction
Authors: Zheng Cheng , Sun Xueqin , Qin Yanxi , Li Junfeng , Jin Guoqiang , Tong Xili , Yang Nianjun 
Published: December 2023

The design of advanced supports to boost the oxygen reduction reaction (ORR) in acidic media is of great significance for proton exchange membrane fuel cells. Herein, TiC@TiO2‐C supports are prepared by the sol–gel method coupled with high‐temperature annealing. The obtained Pt/TiC@TiO2‐C catalyst exhibits outstanding ORR activity such as the half‐wave potential of 0.84 VRHE as well as strong electrochemical stability in 0.1 m HClO4 electrolyte, surpassing the Pt/TiO2‐C and Pt/C catalyst. This result is attributed to the electron transfer from the support to Pt nanoparticles accelerated by the TiC core, which optimizes the electronic structure of Pt to boost the ORR.
A meta‐analysis of U.S. food demand elasticities to detect the impacts of scanner data
Authors: Jeon Younghyeon , Hoang Hoa , Thompson Wyatt , Abler David 
Published: December 2023

AbstractThis paper investigates how scanner data affect demand elasticity estimates and develops methods for scientists to adapt estimated elasticities to analyses of specific policies. We conduct a meta‐analysis of U.S. demand elasticities and find evidence that scanner data generate statistically different elasticities, with more elastic demand than other data types. Own‐price elasticity estimates from household scanner quantity data appear to be more elastic than other quantity types. Household‐level estimates using retail scanner price data, as proxies for prices, tend to be more price‐elastic than other price types. These results suggest caution or adjustment when selecting elasticities for policy analysis.
Does chronic exposure to moderate hypoxia affect growth, physiological and oxidative stress biomarkers in adult spotted wolffish (Anarhichas minor) and the hybrid A. minor × A. lupus?
Authors: François N. R. Le , Drouin‐Johnson C. , Larouche F. , Chabot D. , Blier P. U. 
Published: December 2023

AbstractBoth in their natural habitat (estuaries, marine coastal environment, ocean depths and freshwater lakes) or in captivity conditions (land‐based, open‐sea aquaculture and aquariums), exposure to hypoxia can have direct detrimental effects on fish growth, reproduction, behaviour and health. The objective of this study was to investigate the effects of chronic exposure of spotted wolffish (Anarhichas minor) (∼1.4 kg) and the interspecific hybrid (A. minor × A. lupus) (∼600 g) to moderate hypoxia levels (dissolved oxygen [DO]: 40%, 50% and 60% saturation) in comparison to a normoxia group (control 100%) over a period of 14 weeks at ∼7.5°C. The trials were conducted as a common‐garden experiment (both fish groups reared together) in quadruplicate (4 tanks per DO level = 16 tanks). Fish performance (specific growth rate, feed intake [FI]) and physiological status (condition factor [K] and hepatosomatic index, haematocrit) were monitored at different intervals. The metabolic enzyme activity of citrate synthase (CS), lactate dehydrogenase (LDH) and pyruvate kinase (PK) was measured as well as antioxidant enzymes glutathione reductase and catalase. Oxidative stress indices were assessed by the quantification of thiobarbituric acid reactive substances (TBARS) and the measurement of the enzymatic activity level of aconitase. Significant reduction in growth rate occurred at DO 40%. DO was identified as a major driver of FI. Our results indicate a very strong adaptation to hypoxia as (1) exposures to DO 40% were not severe enough to affect aerobic or anaerobic metabolism capacity or to significantly induce oxidative stress and (2) metabolic organization of the muscle tissue, as expressed by LDH, CS and PK is not affected by DO levels down to 40%. However, at the lowest DO levels (40% and 50%), hybrid fish displayed significantly better growth than the spotted wolffish.
Clinical parameter‐guided initial resuscitation in adult patients with septic shock: A systematic review and network meta‐analysis
Authors: Yumoto Tetsuya , Kuribara Tomoki , Yamada Kohei , Sato Takehito , Koba Shigeru , Tetsuhara Kenichi , Kashiura Masahiro , Sakuraya Masaaki 
Published: December 2023

AbstractAimTo identify the most useful tissue perfusion parameter for initial resuscitation in sepsis/septic shock adults using a network meta‐analysis.MethodsWe searched major databases until December 2022 for randomized trials comparing four tissue perfusion parameters or against usual care. The primary outcome was short‐term mortality up to 90 days. The Confidence in Network Meta‐Analysis web application was used to assess the quality of evidence.ResultsSeventeen trials were identified. Lactate‐guided therapy (risk ratios, 0.59; 95% confidence intervals [0.45–0.76]; high certainty) and capillary refill time‐guided therapy (risk ratios, 0.53; 95% confidence intervals [0.33–0.86]; high certainty) were significantly associated with lower short‐term mortality compared with usual care, whereas central venous oxygen saturation‐guided therapy (risk ratio, 1.50; 95% confidence intervals [1.16–1.94]; moderate certainty) increased the risk of short‐term mortality compared with lactate‐guided therapy.ConclusionsLactate or capillary refill time‐guided initial resuscitation for sepsis/septic shock patients may decrease short‐term mortality. More research is essential to personalize and optimize treatment strategies for septic shock resuscitation.
Cerebral Small Vessel Disease Burden for Bleeding Risk during Antithrombotic Therapy: Bleeding with Antithrombotic Therapy 2 Study
Authors: Tanaka Kanta , Miwa Kaori , Koga Masatoshi , Yoshimura Sohei , Kamiyama Kenji , Yagita Yoshiki , Nagakane Yoshinari , Hoshino Haruhiko , Terasaki Tadashi , Okada Yasushi , Yakushiji Yusuke , Takahashi Shinichi , Ueda Toshihiro , Hasegawa Yasuhiro , Shiozawa Masayuki , Sasaki Makoto , Kudo Kohsuke , Tanaka Jun , Nishihara Masashi , Yamaguchi Yoshitaka , Fujita Kyohei , Honda Yuko , Kawano Hiroyuki , Ide Toshihiro , Yoshimoto Takeshi , Ihara Masafumi , Hirano Teruyuki , Toyoda Kazunori ,   Bleeding with Antithrombotic Therapy 2 Investigators
Published: December 2023

ObjectiveThis study was undertaken to determine the excess risk of antithrombotic‐related bleeding due to cerebral small vessel disease (SVD) burden.MethodsIn this observational, prospective cohort study, patients with cerebrovascular or cardiovascular diseases taking oral antithrombotic agents were enrolled from 52 hospitals across Japan between 2016 and 2019. Baseline multimodal magnetic resonance imaging acquired under prespecified conditions was assessed by a central diagnostic radiology committee to calculate total SVD score. The primary outcome was major bleeding. Secondary outcomes included bleeding at each site and ischemic events.ResultsOf the analyzed 5,250 patients (1,736 women; median age = 73 years, 9,933 patient‐years of follow‐up), antiplatelets and anticoagulants were administered at baseline in 3,948 and 1,565, respectively. Median SVD score was 2 (interquartile range = 1–3). Incidence rate of major bleeding was 0.39 (per 100 patinet‐years) in score 0, 0.56 in score 1, 0.91 in score 2, 1.35 in score 3, and 2.24 in score 4 (adjusted hazard ratio [aHR] for score 4 vs 0 = 5.47, 95% confidence interval [CI] = 2.26–13.23), that of intracranial hemorrhage was 0.11, 0.33, 0.58, 0.99, and 1.06, respectively (aHR = 9.29, 95% CI = 1.99–43.35), and that of ischemic event was 1.82, 2.27, 3.04, 3.91, and 4.07, respectively (aHR = 1.76, 95% CI = 1.08–2.86). In addition, extracranial major bleeding (aHR = 3.43, 95% CI = 1.13–10.38) and gastrointestinal bleeding (aHR = 2.54, 95% CI = 1.02–6.35) significantly increased in SVD score 4 compared to score 0.InterpretationTotal SVD score was predictive for intracranial hemorrhage and probably for extracranial bleeding, suggesting the broader clinical relevance of cerebral SVD as a marker for safe implementation of antithrombotic therapy. ANN NEUROL 2024;95:774–787
Controllable exfoliation of hexagonal boron nitride and tailored three‐dimensional network for highly thermally conductive polymer composites
Authors: Lin Jing , Dong Jin , Chen Bing , Liang Jiayuan , Zhang Hebai , He Zhenguo , He Jiafa , Zhong Rongjian , Liang Xuyun , Hu Dechao 
Published: December 2023

AbstractThermally conductive but electrically insulating composites have become significant components for efficient thermal dissipation in electronic devices due to their miniaturization, integration, and functionalization. Over the past decade, extensive efforts have been dedicated to improving the thermal conductivity of polymer‐based composites through incorporating various thermally conductive fillers. In particular, boron nitride nanosheets (BNNS) with outstanding intrinsic thermal conductivity, electrical insulation, and chemical stability, have sparked intensive interest from researchers. However, BNNS usually suffers from severe aggregation in polymer matrices, leading to high interfacial thermal resistance. Rational construction of three‐dimensional (3D) BNNS continuous networks is crucial for efficient thermal transport and has also been established as a feasible and effective approach to achieve significant enhancement of thermal conductivity for polymer/BNNS composites. In this brief review, we summarized and introduced recent progress on the controllable exfoliation of h‐BN and tailored three‐dimensional networks for highly thermally conductive polymer composites. The fabrication strategies for 3D BNNS networks and the structure–properties relationships of polymer/BNNS composites are highlighted. Finally, the opportunities and challenges for polymer/BNNS composites based on 3D thermally conductive networks are prospected.
Functionalized liquid polyisoprene as a promising toughening agent for poly(lactic acid): Combining stiffness and toughness
Authors: Cordeiro Elisangela , Schmitz Debora Pereira , Soares Bluma Guenther 
Published: December 2023

AbstractLiquid polyisoprene rubbers (LIR) containing anhydride and carboxylic groups along their chains were successfully employed as toughening agent for poly(lactic acid) (PLA) without great influence on the stiffness of the matrix. In fact, the addition of 5% of these functionalized LIR resulted in an improvement of toughness and impact resistance of more than 2000%, whereas the reduction of the yield stress stayed in the range of 12%. No significant variation of the Young modulus was observed for the modified PLA samples. The effect of the LIR on the rheological and thermal properties of PLA was also investigated. The glass transition temperature obtained from dynamic‐mechanical analysis of the PLA matrix was not affected by the addition of 10% of the liquid rubber. The scanning electron microscopy analysis revealed a significant decrease in the rubber domains for the blends containing LIR functionalized with anhydride groups. Finally, the modified PLA with anhydride‐functionalized LIR was able to produce transparent film with outstanding mechanical performance than neat PLA, making this material a good option for food packaging.
Oxygen Vacancies Riched PrOx Polycrystalline Nanorods on Graphene Nanosheets as Advanced Oxygen Catalysts for Lithium‐Oxygen Batteries
Authors: Zhan Xingyi , Zhang Yifan , Su Liwei , Zhang Lei , Tong Zijin , Wu Hao , Wang Lianbang , Wang Yuanhao , Wang Xiaoxiang 
Published: December 2023

AbstractThe slow reaction kinetics of Li−O is currently the most pressing technical obstacle to the development of lithium‐oxygen batteries. The Li2O2′s growth/decomposition pathways dominate the battery performance and can be optimized by exploring efficient cathode catalysts. Herein, we prepare regular, polycrystalline, oxygen vacancy (VO)‐riched PrOx uniformly anchored on few‐layered graphene (FLG) nanosheets to boost the Li−O reactions. XRD, TGA, XPS, SEM, TEM, SEAD, and electrochemical test techniques are used to study their chemical composition, microstructure, battery performance, and the effect of FLG on the formation of polycrystalline and VO. It is confirmed that FLG provides a large specific surface area and good electron transport. Moreover, it works as an anchoring substrate to transform PrOx from single crystal to polycrystalline, which is beneficial for exposing catalytic sites and VO and improving the battery performance. This unique composition and structure offer efficient active sites, accelerate electron transport, and regulate the Li2O2′s nucleation to form nanofilms or nanosheets on the catalyst. With this cathode catalyst, the battery achieved an ultralow total overpotential of 0.618 V, with a discharge capacity of 11489 mAh g−1 in the ultimate‐capacity mode and a superior cyclability of 85 cycles under the limited capacity of 500 mAh g−1.