bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic review of auditory processing abilities in children with non-syndromic cleft lip and/or palate
Authors: Banumathi  , Jain Chandni 
Published: January 2024

Abstract

Purpose:
The present systematic review aims to understand auditory processing abilities in children with nonsyndromic cleft lip and/or palate (NSCL/P). The review summarizes questionnaire, behavioral, and electrophysiological findings of auditory processing abilities in children with NSCL/P.

Method:
The study used a literature search of electronic databases (e.g., Pub Med, Google Scholar, J Stage, Research Gate, ScienceDirect) and the AIISH repository from 2000 to 2021. The retrieved articles were assessed in two stages: title and abstract screening, followed by a full-length article review. About 13 articles were selected after the full-length review of 17 shortlisted articles. All selected studies used cohort design.

Result:
The review showed that speech perception in noise and temporal processing were the majorly affected processing abilities in children with NSCL/P. The review also showed that cleft palate children are more prone to auditory processing deficits than other cleft subgroups. These auditory processing deficits in NSCL/P children may cause delayed speech and language skills, reading, and learning disabilities, which are highly reported in these children.

Conclusion:
Auditory processing evaluation should be a part of the audiological test battery for these children to promote early diagnosis and management.
Prevalence and correlates of cyberchondria among professionals working in the information technology sector in Chennai, India
Authors: Makarla S , Gopichandran V , Tondare D 
Published: January 2024

Background:
Cyberchondria is the excessive searching of online health information that leads to anxiety and distress. There is scarce information about its prevalence in low and middle-income country settings.

Objectives:
The objective of the study was to assess the prevalence and factors influencing cyberchondria among employees working in the information technology sector in India.

Methods:
An emailed questionnaire-based cross-sectional survey was conducted among 205 employees working in various information technology firms in and around Chennai. The data were analyzed using nonhierarchical k-means cluster analysis to group participants with and without cyberchondria on its four subdomains. The association of cyberchondria with general mental health as measured by the General Health Questionnaire 12 was studied using independent sample t-test. Logistic regression analysis was performed to study the association between general mental health and cyberchondria after adjusting for sociodemographic covariates.

Results:
The prevalence of cyberchondria was 55.6%. The dominant pattern was excessiveness of online searching, requirement of reassurance followed by distress due to health anxiety, and compulsivity. Cyberchondria was negatively associated with general mental health (adj. OR 0.923; 95% CI 0.882–0.967) after adjusting for age, sex, education, and years of service.

Conclusions:
Cyberchondria is an emerging public mental health problem in India. Since it is associated with poor mental health, measures need to be adopted to evaluate, prevent, and treat it at the population level.
Respectful maternity care during childbirth in India
Authors: Ansari H , Yeravdekar R 
Published: January 2024

Background:
Respectful maternity care is a rightful expectation of women. However, disrespectful maternity care is prevalent in various settings. Therefore, a systematic review and meta-analysis were conducted to identify various forms of ill-treatment, determinants, and pooled prevalence of disrespectful maternity care in India.

Methods:
A systematic review was performed in various databases. After quality assessment, seven studies were included. Pooled prevalence was estimated using the inverse variance method and the random-effects model using Review Manager Software.

Results:
Individual study prevalence ranged from 20.9% to 100%. The overall pooled prevalence of disrespectful maternity care was 71.31% (95% CI 39.84–102.78). Pooled prevalence in community-based studies was 77.32% (95% CI 56.71–97.93), which was higher as compared to studies conducted in health facilities, this being 65.38% (95% CI 15.76–115.01). The highest reported form of ill-treatment was non-consent (49.84%), verbal abuse (25.75%) followed by threats (23.25%), physical abuse (16.96%), and discrimination (14.79%). Besides, other factors identified included lack of dignity, delivery by unqualified personnel, lack of privacy, demand for informal payments, and lack of basic infrastructure, hygiene, and sanitation. The determinants identified for disrespect and abuse were sociocultural factors including age, socioeconomic status, caste, parity, women autonomy, empowerment, comorbidities, and environmental factors including infrastructural issues, overcrowding, ill-equipped health facilities, supply constraints, and healthcare access.

Results:
Individual study prevalence ranged from 20.9% to 100%. The overall pooled prevalence of disrespectful maternity care was 71.31% (95% CI 39.84–102.78). Pooled prevalence in community-based studies was 77.32% (95% CI 56.71–97.93), which was higher as compared to studies conducted in health facilities, this being 65.38% (95% CI 15.76–115.01). The highest reported form of ill-treatment was non-consent (49.84%), verbal abuse (25.75%) followed by threats (23.25%), physical abuse (16.96%), and discrimination (14.79%). Besides, other factors identified included lack of dignity, delivery by unqualified personnel, lack of privacy, demand for informal payments, and lack of basic infrastructure, hygiene, and sanitation. The determinants identified for disrespect and abuse were sociocultural factors including age, socioeconomic status, caste, parity, women autonomy, empowerment, comorbidities, and environmental factors including infrastructural issues, overcrowding, ill-equipped health facilities, supply constraints, and healthcare access.

Conclusion:
The high prevalence of disrespectful maternity care indicates an urgent need to improve maternity care in India by making it more respectful, dignified, and women-centered. Interventions, policies, and programs should be implemented that will protect the fundamental rights of women.
Effect of testosterone replacement therapy on insulin sensitivity and body composition in congenital hypogonadism
Authors: Reddy KCO , Yadav SB 
Published: January 2024

Aims:
To evaluate the prevalence of metabolic syndrome (MS) and whole-body composition in patients with congenital hypogonadism and investigate the effects of replacement therapy with testosterone undecanoate on MS, insulin resistance (IR), and whole-body composition in subset of patients.

Methods:
In a single arm prospective longitudinal intervention study, 33 patients with congenital hypogonadism, ages 20–39 years, were recruited and their parameters of MS, whole-body composition by DXA were compared with age and BMI matched healthy controls. In 21 patients, after 9 months we prospectively studied the effect (pre–post difference) of injection testosterone undecanoate (1,000 mg) replacement on MS, IR, and whole-body compositions.

Results:
The prevalence of MS was similar in patients and controls (27.3% vs. 9.1%, P = 0.05). Hypogonadism patients had higher prevalence of hypertension (33% vs. 3%, P < 0.01). Patients had decrease in lean body mass (P < 0.05) as compared to controls. After testosterone replacement, there was significant decrease in waist circumference (88.6 ± 13.1 cm vs. 83.9 ± 12.9 cm, P < 0.01), truncal fat (25.9 ± 7.3% vs. 24.0 ± 6.3%, P < 0.05), fasting C-peptide (2.1 ± 0.79 ng/ml vs. 0.68 ± 0.23 ng/ml, P < 0.01), serum proinsulin [1.43 (0.32– 13.4) vs. 0.5 (0.5–3.2) pmol/l, P < 0.001] and a significant increase in lean body mass (46,906 ± 8,876 gm vs. 50,083 ± 7,590 gm, P < 0.001). Homeostasis model assessment of insulin resistance (HOMA-IR) (4.6 ± 1.7 vs. 0.5 ± 0.2, P < 0.001) and homeostatic model for assessment of insulin sensitivity (HOMA%S) [21 (12–65) vs. 206 (125–714), P < 0.001] were improved significantly following testosterone replacement.

Conclusion:
In this study, 36 weeks of testosterone replacement resulted in significant decrease in waist circumference, IR, truncal fat, total body fat and improvement in lean body mass, and insulin sensitivity.
Performance Challenges in a Newly Established Clean Room at Omid Hospital, Isfahan, Iran: A Descriptive Study
Authors: Vaez Mehrnaz , Sharifi Mehran , Karimi Sahar , Moghaddas Azadeh 
Published: January 2024

Objective:
This study aimed to comprehensively assess the challenges faced by a newly established clean room in the oncology center of Omid Hospital, Isfahan, Iran, one of the first of its kind in the country. The research also sought to identify the underlying causes of these challenges and propose potential solutions to address them.

Methods:
A 6-month cross-sectional study was conducted from December 2021 to May 2022. International guidelines such as British Columbia Cancer Agencies’ guideline of hazardous drugs, the National Institute for Occupational Safety and Health guideline for working with hazardous drugs, and United States pharmacopeia related to cleanroom performance were studied, translated, and summarized into a checklist. The staff performance in Omid Hospital’s clean room was compared to the data collection form, and all medication errors were documented and analyzed. The study also explained the underlying causes of these challenges and proposed potential solutions.

Findings:
Among 1005 chemotherapy regimens, 836 errors were detected, stemming from issues such as engineering and construction challenges, lack of human resources and essential equipment, and budgetary constraints.

Conclusion:
Despite the involvement of a trained oncology clinical pharmacist, Omid Hospital’s cleanroom faces significant challenges within the medical and hospital system, leading to non-standard challenges. The study recommends multidisciplinary approaches in the hospital to mitigate these challenges and improve cleanroom performance.
Comparing Sequential Organ Failure Assessment Score, Acute Physiology and Chronic Health Evaluation II, Modified Acute Physiology and Chronic Health Evaluation II, Simplified Acute Physiology Score II and Poisoning Severity Score for Outcome Prediction of Pesticide Poisoned Patients Admitted to the Intensive Care Unit
Authors: Dorooshi Gholamali , Samsamshariat Shiva , Gheshlaghi Farzad , Zoofaghari Shafeajafar , Hasanzadeh Akbar , Abbasi Saeed , Eizadi-Mood Nastaran 
Published: January 2024

Objective:
This study aimed to assess the severity of poisoning, various scoring systems, including Sequential Organ Failure Assessment (SOFA) score, acute physiology and chronic health evaluation II (APACHE II), Simplified Acute Physiology Score (SAPS II), Modified APACHE II, and poisoning severity score (PSS) were used. In this study, we compared the predictive value of these scoring systems on the outcome of pesticide-poisoned patients.

Methods:
This is a cross-sectional study of pesticide-poisoned patients (140 patients) who were admitted to the intensive care unit (ICU) of Khorshid Hospital, Isfahan, Iran, between January 2015 and 2019. The area under the receiver operating characteristic (AUC) curve and the predictive value of scoring systems were compared.

Findings:
Poisoning was higher in the male population (72.8%). The causes of poisoning were paraquat, (38.6%), aluminum phosphide, (32.1%), and organophosphate, (29.3%). The mean age of the patients was 33.9 years. Most patients (79.3%) attempted suicide. The mortality rate was 46.43%. The mean of “SOFA score,” “APACHE II,” “SAPS II,” “Modified APACHE II,” and “PSS” was 5.9; 15.7; 30.02; 15.8; and 1.9, respectively. There was a significant difference in the mean of all scoring systems for outcome prediction. Among all scoring systems, the SAPS II score with the cutoff point (16.5) had the best criteria for outcome prediction (AUC (0.831 ± 0.037), sensitivity (83.1%, 95% confidence interval [CI]: [71.7–91.2]), specificity (75.7%, 95% CI: [64.3–84.9]), positive predictive values (75.0%, 95% CI: [66.4–82.0]), negative predictive values (83.6%, 95% CI: [74.5–89.9]).

Conclusion:
The SAPS II scoring system may be a suitable indicator for outcome predictions in pesticide-poisoned patients in the ICU.
Risk factors for corneal endothelial cell loss after phacoemulsification
Authors: Lee Natalie Si-Yi , Ong Keith 
Published: January 2024

Abstract:

PURPOSE:
The purpose of this study was to evaluate the changes in corneal endothelial cell density (CECD) occurring after cataract phacoemulsification surgery and identify factors associated with cell loss.

MATERIALS AND METHODS:
This was a retrospective study involving patients who underwent cataract phacoemulsification surgery between January 1, 2018, and December 31, 2018, at two private hospitals. Demographic data and biometric parameters were obtained preoperatively. Ultrasound metrics were recorded for each operation, including total on time (TOT), total equivalent power in position 3, and cumulative dissipated energy (CDE). Using corneal specular microscopy, CECD was measured preoperatively and postoperatively at 12, 24, and 36 months. Factors associated with decreased CECD were identified.

RESULTS:
This study included 223 eyes of 133 patients. The mean CECD was 2530.03 ± 285.42 cells/mm2 preoperatively and significantly decreased to 2364.22 ± 386.98 cells/mm2 at 12 months (P < 0.001), 2292.32 ± 319.72 cells/mm2 at 24 months (P < 0.001), and 2242.85 ± 363.65 cells/mm2 at 36 months (P < 0.001). The amount of cell loss was associated with age, gender, preoperative CECD, preoperative anterior chamber depth, lens thickness, TOT, and CDE. Using multivariate analysis, age, preoperative CECD, and TOT were identified as independent predictors for CECD loss 12 months after surgery.

CONCLUSION:
The greatest decrease in CECD occurred during the first year after cataract surgery, and the amount of cell loss was influenced by both baseline patient characteristics and ultrasound metrics. Longer-term prospective studies in a larger cohort may yield more information.
Dantu Blood Group Erythrocytes Form Large Plasmodium falciparum Rosettes Less Commonly
Authors: Carlier Molly S. A. , Nyamu Wilfred , Makale Johnstone , Williams Thomas N. , Rowe J. Alexandra , Kariuki Silvia N. 
Published: January 2024

ABSTRACT.
Dantu erythrocytes, which express a hybrid glycophorin B/A protein, are protective against severe malaria. Recent studies have shown that Dantu impairs Plasmodium falciparum invasion by increasing erythrocyte membrane tension, but its effects on pathological host–parasite adhesion interactions such as rosetting, the binding of uninfected erythrocytes to P. falciparum–infected erythrocytes, have not been investigated previously. The expression of several putative host rosetting receptors—including glycophorin A (GYPA), glycophorin C (GYPC), complement receptor 1 (CR1), and band 3, which complexes with GYPA to form the Wrightb blood group antigen—are altered on Dantu erythrocytes. Here, we compare receptor expression, and rosetting at both 1 hour and 48 hours after mixing with mature trophozoite-stage Kenyan laboratory–adapted P. falciparum strain 11019 parasites in Dantu and non-Dantu erythrocytes. Dantu erythrocytes showed lower staining for GYPA and CR1, and greater staining for band 3, as observed previously, whereas Wrightb and GYPC staining did not vary significantly. No significant between-genotype differences in rosetting were seen after 1 hour, but the percentage of large rosettes was significantly less in both Dantu heterozygous (mean, 16.4%; standard error of the mean [SEM], 3.2) and homozygous donors (mean, 15.4%; SEM, 1.4) compared with non-Dantu erythrocytes (mean, 32.9%; SEM, 7.1; one-way analysis of variance, P = 0.025) after 48 hours. We also found positive correlations between erythrocyte mean corpuscular volume (MCV), the percentage of large rosettes (Spearman’s rs = 0.5970, P = 0.0043), and mean rosette size (rs = 0.5206, P = 0.0155). Impaired rosetting resulting from altered erythrocyte membrane receptor expression and reduced MCV might add to the protective effect of Dantu against severe malaria.
Case Report: A Case of Complicated Typhoid Fever with Rhabdomyolysis and Hemophagocytic Lymphohistiocytosis
Authors: Selvam Suresh , Singh Harpreet , Seth Sonal , Suri Vikas , Bhalla Ashish , Sachdeva Man Updesh Singh 
Published: January 2024

ABSTRACT.
Typhoid fever can have diverse extra-intestinal complications including encephalitis, Guillain-Barré syndrome, endocarditis, myocarditis, osteomyelitis, renal abscess, and splenic abscesses. Secondary hemophagocytic lymphohistiocytosis with rhabdomyolysis is a rare complication of typhoid fever. Here, we present the case of an adolescent with typhoid fever complicated by rhabdomyolysis and hemophagocytic lymphohistiocytosis.
Riskli Gebelerde Posttravmatik Stres Bozukluğu Belirtileri, Doğum ve Doğum Sonrası Döneme İlişkin Endişelerin Belirlenmesi
Authors: ERTEKİN PINAR Şükran , DEMİREL Gülbahtiyar 
Published: January 2024

Amaç: Kadının riskli gebelik tanısı alması, bebeğini kaybetme korkusu ve destek faktörlerinin yetersizliği endişe düzeylerini artırabilmekte ve posttravmatik stres bozukluklarına da neden olabilmektedir Araştırma, yüksek ve düşük riskli gebelerde posttravmatik stres bozukluğu belirtileri, doğum ve doğum sonrası döneme ilişkin endişelerin belirlenmesi amacı ile yapılmıştır.
Yöntem: Araştırma kesitsel desende yürütülmüştür. Çalışmanın örneklemini bir devlet hastanesinin gebe ve jinekoloji servislerine yüksek riskli gebelik tanısı ile yatan (n=306), kadın hastalıkları ve doğum polikliniğine kontrol amacı ile başvuran (n=306) toplam 612 gebe oluşturmuştur. Veriler Kişisel Bilgi Formu, Posttravmatik Stres Bozukluğu Soru Listesi-Sivil Versiyonu, Doğum ve Doğum Sonrası Döneme İlişkin Endişeler Ölçeği ile toplanmıştır.
Bulgular: Yüksek riskli gebelerin %48.4’ünde ve düşük riskli gebelerin %29.4’ünde posttravmatik stres bozukluğu belirtileri olduğu saptanmıştır. Yüksek ve düşük riskli gebelerde toplam Posttravmatik Stres Bozukluğu Soru Listesi-Sivil Versiyonu ve toplam Doğum ve Doğum Sonrası Döneme İlişkin Endişeler Ölçeği puanları arasında istatistiksel olarak anlamlı farklılık bulunmuştur (p
Multi-Dimensional Standard Measurement of the level of Marital Relationship in Saudi Society
Authors: Al-Amri Mona Sa’ad Faleh 
Published: January 2024

The objective of this study was to produce a standardized measurement scale of marital relations using a random sample of Saudi married couples. The study adhered to the traditional scientific paradigm where a quantitative research method is employed to reveal the construction of the scale. The study sample consisted of (1339) individuals. The measurement scale is defined by the following five axes to the marital relationship: [1] the axis of the social relationship, [2] the axis of intellectual relationship, [3] the axis of the emotional relationship, [4] the axis of the sexual relationship, and [5] the axis of the behavioral relationship. The reliability of the internal consistency of the scale as a whole was (0.87), which indicated that the scale has a high degree of reliability.
The level of marital relationship as a whole among members of Saudi society was high, with a mean of (4.06). While the dimensions came in the following order: the behavioral relationship was in the first rank, with a mean of (4.36), then the sexual relationship was in the second rank, with a mean of (4.09), then the social relationship was in the third rank, with a mean of (4.00), then the emotional relationship was in the fourth rank, with a mean of (3.87). Finally, the intellectual relationship with a mean of (3.84).
Strategi Komunikasi Krisis DPR RI Menggunakan Instagram Menghadapi Penolakan RUU Cipta Kerja
Authors: Iskandar Indra None , Hidayat Dadang Rahmat , Priyatna Centurion Chandratama 
Published: January 2024

The following study analyzes the social media strategy of the DPR RI’s Instagram facing the rejection of the Job Creation Bill on social media. The rejection on social media using hashtags #TolakOmnibusLaw Job Creation. The study uses Coombs situational crisis communication theory (SCCT) model as a framework for understanding and suggesting future crisis communication strategies using social media selections. The result from this research shows that the DPR RI’s Instagram is an effective tool for monitoring and engaging public discourse during the #TolakOmnibusLaw Job Creation crisis. This study explores the ideas presented by the DPR RI’s Instagram on 14 April 2020, the first time the Job Creation Bill was discussed until President Joko “Jokowi” Widodo officially signed the Job Creation Bill into Law No. 11 of 2020 on November 2, 2020. From the data collected, this research found 17 posts related to the Job Creation Bill. From the analysis of 17 posts, this study concludes that the dominant strategy from the DPR RI Instagram is denial. Denial strategy with denial tactics based on the SCCT Coombs theory is an effective strategy in facing many hoaxes in the Job Creation Bill’s crisis.Abstrak:Studi ini menganalisis strategi media sosial pada masa krisis yang harus dihadapi DPR RI akibat adanya penolakan pengesahan Rancangan Undang-Undang (RUU) Cipta Kerja menjadi Undang-Undang (UU) yang terjadi di media sosial. Penolakan tersebut dilancarkan dengan menggunakan #TolakOmnibusLaw. Studi ini menggunakan situational crisis communication theory (SCCT), model yang digagas oleh Coombs sebagai kerangka berpikir untuk memahami dan merekomendasikan strategi komunikasi krisis menggunakan media sosial dengan studi kasus terhadap akun Instagram DPR RI. Hasil dari penelitian menunjukkan bahwa akun Instagram DPR RI menjadi alat yang efektif untuk memonitor dan meng-engage perbincangan publik pada masa krisis #TolakOmnibusLaw. Studi ini menganalisis gagasan yang ada pada unggahan akun Instagram DPR RI mulai 14 April 2020 yang merupakan tanggal RUU Cipta Kerja pertama kali dibahas di DPR RI hingga saat Presiden Joko “Jokowi” Widodo menandatangani UU No.11 Tahun 2020 pada 2 November 2020. Berdasarkan pengumpulan data diperoleh 17 unggahan terkait dengan RUU Cipta Kerja. Dari hasil analisis terhadap ke-17 unggahan disimpulkan bahwa strategi dominan dari akun resmi Instagram DPR RI dalam menghadapi penolakan terhadap RUU Cipta Kerja adalah denial. Strategi denial dengan taktik denial berdasarkan teori SCCT Coombs merupakan strategi yang efektif menghadapi banyaknya hoaks dalam krisis yang disebabkan penolakan pengesahan RUU Cipta Kerja menjadi UU.