bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characteristics of tickborne infections in the underexplored areas of the Trans-Baikal Territory
Authors: Lagunova E. K. , Khasnatinov M. A. , Danchinova G. A. 
Published: January 2024

Background. Infections transmitted to humans by the bites of ixodid ticks remain an urgent public health problem. In this work we explored the natural foci of tickborne infections located in the valley of the Chikoy River, which is a part of the buffer zone of the Baikal natural territory.The aim. To characterize the modern diversity and prevalence of tick-borne pathogens in the ecosystems of the valley of the Chikoy River (Trans-Baikal Territory, Russian Federation).Materials and methods. Thirteen sampling sites were located in typical biotopes throughout the Chikoy valley. In total 48 adult Ixodes persulcatus ticks, 1 female Haemaphysalis concinna tick and 38 specimens of small mammals were studied. All samples were tested for infection with seven tick-borne pathogens using multiplex real-time PCR.Results. No pathogens were detected in the H. concinna specimen. No R. sibirica and R. heilongjiangensis were detected both in ticks and in rodents. Among I. persulcatus, tick-borne encephalitis virus (TBEV), and the prevalence of Borrelia burgdorferi s. l. comprised 39.5 %, A. phagocytophilum – 16.7 %, B. miyamotoi – 8.3 % and Ehrlichia sp. – 2.1 %. Among infected ticks 6.2 % were co-infected with B. burgdorferi s. l. and A. phagocytophilum. Four rodent hosts of ticks and infections were identified: Myodes rufocanus (44.7 %), Apodemus peninsulae (39 %), Microtus oeconomus (13.2 %) and M. rutilus (2.6 %). Mean prevalence of B. burgdorferi s. l. in rodents comprised 39.5 %, B. miyamotoi – 28.9 %, Ehrlichia sp. – 21.1 % and A. phagocytophilum – 18.4 %. TBEV was detected in 5.3 % of rodents.Conclusion. At least five tick-borne pathogens circulate in the Chikoi River valley, i. e. TBEV, B. burgdorferi sensu lato, A. phagocytophilum, B. miyamotoi and Ehrlichia sp. The wide spread of I. persulcatus and abundance of competent rodent hosts of infections and ticks indicates that natural foci of tick-borne diseases are widely distributed in the Chikoi River valley.
The rs11385942 and rs657152 variants are not associated with COVID-19 severity and outcomes in patients treated with favipiravir and remdesivir
Authors: Abdullaev Sh. P. , Denisenko N. P. , Temirbulatov I. I. , Kachanova A. A. , Tuchkova S. N. , Mikhaylenko E. V. , Kryukov A. V. , Valiev T. T. , Mirzaev K. B. , Sychev D. A. 
Published: January 2024

Background. There is a mounting evidence in the scientific literature that susceptibility to SARS-CoV-2 infection could vary. The severity of COVID-19 symptoms can range from asymptomatic to severe respiratory failure, requiring prolonged artificial ventilation. The underlying causes of this range of clinical manifestations remain unclear. Identification of the risk factors that may cause this variation in clinical symptoms is important for identifying the most susceptible populations at highest risk. This should help improve prevention measures, reduce hospitalizations, and decrease the mortality rate of the disease. Previously, an association has been found between the severity of COVID-19 and the genetic markers rs11385942 G>GA and rs657152 A>C.The aim. To assess the impact of carrying polymorphic markers rs11385942 G>GA and rs657152 A>C on the severity of COVID-19 in patients undergoing specific therapy. Materials and methods. A total of 240 patients hospitalized with a coronavirus infection were included in the study. All patients received therapy with favipiravir or remdesivir. The presence of the rs11385942 G>GA and rs657152 A>C variants was determined in all patients. The study compared the length of hospital stays, frequency of patient transfers to the intensive care unit (ICU), and frequency of clinical outcomes (recovery or death) among carriers of allelic variants of the markers under investigation.Results. There were no significant associations between the carriage of variants rs11385942 G>GA and rs657152 A>C and the duration of patients’ hospitalization, frequency of patient transfers to the ICU, and patient outcomes.Conclusion. The carriage of rs11385942 G>GA and rs657152 A>C variants did not affect the severity or type of clinical outcomes in patients with COVID-19.
Production of angiogenesis mediators and the structure of the vascular wall in the heart in ischemic cardiomyopathy
Authors: Chumakova S. P. , Urazova O. I. , Shipulin V. M. , Sukhodolo I. V. , Stelmashenko A. I. , Denisenko O. A. , Andreev S. L. , Demin M. S. , Churina E. G. 
Published: January 2024

Background. In the pathogenesis of ischemic cardiomyopathy (ICMP), angiopoiesis remains unexplored.The aim. To describe the vasculature of the heart and the imbalance of angiogenesis mediators in the coronary circulation in association with the number of endothelial progenitor cells (EPC) and desquamated endothelial cells (DEC) in the blood of patients with coronary heart disease (CHD), suffering and not suffering from ICMP.Methods. Fifty-two patients with CHD (30 patients with ICMP, 22 patients without ICMP), 15 healthy donors were examined. The content of EPC (CD14+CD34+VEGFR2+) in the blood from the cubital vein and DEC (CD45–CD146+) in the blood from the coronary sinus and the cubital vein was determined by flow cytometry. The concentrations of VEGF-A (vascular endothelial growth factor A), PDGF (platelet-derived growth factor), and SDF-1 (stromal cell-derived factor 1) in blood plasma were recorded using immunofluorescence assay; the angiopoietin-2, MMP-9 (matrix metallopeptidase 9) were recorded using enzyme immunoassay. In myocardial biopsies the specific area of vessels and the expression of αSMA (smooth muscle alpha-actin) were determined by morphometric and immunohistochemical methods.Results. In the peripheral blood of patients with CHD, regardless of the presence of ICMP, the DEC content exceeded the physiological level, and the VEGF-A, PDGF, angiopoietin-2, and MMP-9 corresponded to the norm. In CHD patients without cardiomyopathy, there was an excess of SDF-1 and EPC in the blood from the cubital vein, and in ICMP, their physiological significance was noted. In the coronary blood flow in patients with CHD without cardiomyopathy, an increase in the concentration of PDGF was found, which was not determined in patients with ICMP, who had an increased content of DEC, angiopoietin-2 and MMP-9. The specific area of the vessels in the patients of the two groups was comparable; the expression of αSMA in ICMP was 6.2 times lower than in patients with CHD without cardiomyopathy.Conclusion. The development of ICMP is accompanied by impaired maturation of vessels in the myocardium, associated with the absence of a compensatory reaction of activation of cellular and humoral factors of angiogenesis.
Upaya Kantor Urusan Agama dalam Mencegah Perkawinan Dini di Kecamatan Lolak, Bolaang Mongondow
Authors: Amiri Kartika Septiani , Paputungan Rahmat 
Published: January 2024

This research focuses on the role of the Office of Religious Affairs/Kantor Urusan Agama (KUA) in reducing early marriage rates and the variables influencing such events in the Lolak Subdistrict, Bolaang Mongondow Regency, North Sulawesi. A qualitative descriptive method with a phenomenological approach is employed to understand participants' experiences regarding early marriage comprehensively. The research results indicate that the KUA plays a crucial role in lowering the incidence of early marriages in the Lolak Subdistrict. They refuse to approve marriages that violate the age limits set by Law Number 16 of 2019. In addition to withholding approval, the KUA also conducts educational programs to provide the community an understanding of these regulations. Islamic guidance is delivered directly in classroom settings to prevent early marriages. This research seeks to uncover the role of the KUA in addressing early marriages and the influencing variables in the Lolak Subdistrict. With an emphasis on education and the refusal to approve early marriages, the KUA is a crucial agent in combating early marriages in the region. Keywords: Office of Religious Affairs; Marriage, Early Age. ABSTRAKPenelitian ini berfokus pada peran Kantor Urusan Agama (KUA) dalam mengurangi angka pernikahan dini serta variabel yang mempengaruhi peristiwa tersebut di Kecamatan Lolak, Kabupaten Bolaang Mongondow, Sulawesi Utara. Metode deskriptif kualitatif dengan pendekatan fenomenologi digunakan untuk mendapatkan gambaran komprehensif terhadap pengalaman partisipan penelitian seputar pernikahan dini. Hasil penelitian menunjukkan bahwa KUA memainkan peran yang penting dalam menurunkan angka pernikahan dini di Kelurahan Lolak. Mereka menolak memberikan persetujuan terhadap pernikahan yang melanggar batasan usia yang ditetapkan dalam Undang-Undang Nomor 16 Tahun 2019. Selain menolak persetujuan, KUA juga menggelar program edukasi untuk memberikan pemahaman kepada masyarakat tentang peraturan tersebut. Bimbingan Islam disampaikan secara langsung dalam setting kelas untuk mencegah terjadinya pernikahan dini. Penelitian ini berusaha mengungkap peran KUA dalam menangani pernikahan dini serta variabel-variabel yang mempengaruhinya di Kecamatan Lolak. Dengan penekanan pada edukasi dan penolakan persetujuan pernikahan dini yang ditentukan, KUA bertindak sebagai agen penting dalam memerangi pernikahan dini di wilayah tersebut.
शैक्षिक सामग्रीको प्रयोगप्रति आधारभूत तहका शिक्षक तथा प्रधानाध्यापकको अवधारणा {Basic Level Techers’ and Headmasters’ Perceptions of the Use of Teaching Materials}
Authors: फुएल fuyal बद्रिप्रसाद Badri Prasad 
Published: January 2024

यस लेखको उद्देश्य आधारभूत तहको सामुदायिक विद्यालयमा शिक्षण गर्ने शिक्षक तथा प्रधानाध्यापकहरूमा शैक्षिक सामग्रीप्रतिको अवधारण पत्ता लगाउने रहेको छ । यो अध्ययन गुणात्मक ढाँचाबाट सम्पन्न गर्ने क्रममा उत्तरदाताबाट शाब्दिक सूचना सङ्कलन गरिएको छ भने सो सूचनाको विश्लेषण पनि व्याख्यात्मक ढङ्गले नै गरिएको छ । अध्ययनका क्रममा प्राथमिक सूचना अध्ययनकर्ता स्वयम् सम्बन्धित क्षेत्रमा उपस्थित भएर नमुना छनोटमा परेका व्यक्तिहरूसँग अन्तर्वार्ता र प्रश्नावलीको उपयोग गरी सङ्कलन गरिएको छ । त्यस्तै अध्ययनसँग सम्बन्धित लिखित रूपमा रहेका प्रकाशित तथा अप्रकाशित सामग्रीहरूबाट द्वितीयक सूचना समेत उपयोग गरिएको छ । प्राथमिक सूचना सङ्कलन गर्न इलाम जिल्लालाई सुविधाका आधारमा छनोट गरी चिट्ठाका माध्यमद्वारा कुल २९४ वटा सामुदायिक विद्यालय मध्येबाट १२० जना शिक्षक र प्रधानाध्यापकलाई समान सम्भावनायुक्त नमुना छनोट विधिबाट छनोट गरिएको छ । अध्ययनको सिलसिलामा आएका सूचनाहरूलाई वर्गीकरण गर्दै विषयगत आधारमा विश्लेषण एवम् छलफल गरिएको छ । छनोटमा परेका सामुदायिक आधारभूत विद्यालयमा शिक्षण गर्ने शिक्षकहरू न्यूनतमभन्दा माथिल्लो शैक्षिक योग्यता हासिल गर्नाका साथै तालिमसमेत प्राप्त गरेको अवस्था हुँदाहुँदै शैक्षिक सामग्रीप्रति उनीहरूमा सकारात्मक अवधारणा साथै शिक्षणलाई प्रभावकारी बनाउने जाँगरको कमी देखिन्छ । शिक्षणमा सामग्रीको प्रयोगले समय खेर फाल्नुका साथै यसको प्रयोगबिना पनि प्रभावकारी शिक्षण गर्न सकिने धारणा राख्नु शिक्षक एवम् प्रधानाध्यापकमा नकारात्मक भावना हावी भएको देखिएको हुँदा यसलाई अनुगमन एवम् पुनर्ताजगी तालिमलाई कार्यशालाका रूपबाट सञ्चालन गरेर उनीहरूको सोचमा सकारात्मक भावनामा ल्याउनु आवश्यक देखिन्छ ।
{The major objective of this study is to explore basic level community school teachers’ and headmasters’ perceptions of teaching materials. In line with the qualitative design, the information has been collected in the verbal form and analyzed descriptively. In the course of the study, the primary information has been collected from the selected individuals by the researcher himself using the interview and the questionnaire as the research tools. Similarly, other published as well as unpublished resources have been utilized as the secondary source of information. For obtaining the primary information, Ilam district has been selected on the convenience basis, and of the total of 294 basic community schools, 120 teachers have been selected as the respondents randomly. The information collected in the course of the study has been thematized and categorized, and then discussed. The study reveals that the teachers and headmasters selected for the study have only a small degree of positive perception and less spirit for teaching even though they have higher qualifications than are required and are trained. It prevails among them that the use of teaching materials is a waste of time and that effective teaching is possible even without teaching materials, meaning ultimately that they have negative perceptions of teaching materials. Hence, it is necessary to bring about positive perceptions among them by means of monitoring and refreshers in the form of workshops.}
Fish Diversity of Ghodaghodi Lake Area: An Important Ramsar Wetland Site, Kailali, Far-Western, Nepal
Authors: K.C. Laba , Shrestha Santoshi , Sigdel Prakash , Chaudhary Dayaram 
Published: January 2024

Fish diversity of Ghodaghodi Lake Area (Ghodaghodi and Nakhrod Lake) from April 2019 to August 2021, covering three seasons; Pre-monsoon (April 2019), Post-monsoon (February 2020), and Monsoon (July 2021) by using conventional and locally accessible fishing gears such as gill nets, cast nets and hook lines in 17 sampling points. A total of 2810 individuals with 39 species, 27 genera, 19 families, and 8 orders were documented. The most common fish species were Pethia ticto, Xenentodon cancila, Notopterus notopterus, Nandus nandus, and Pethia conchonius. The order Cypriniformes accounts for the majority of both Ghodaghodi (42%) and Nakhrod Lake (33%) respectively. The diversity indices were found to be higher in the pre-monsoon season in both Ghodaghodi Lake (2.58) and Nakhrod Lake (1.85), whereas lower in post-monsoon (2.36) in Ghodaghodi Lake and monsoon (1.35) in Nakhrod Lake. Similarly, species richness was highest in the monsoon season (9.33) in Ghodaghodi Lake and pre-monsoon season (3.29) in Nakhrod Lake while it was lowest in the post-monsoon season (4.19), (2.25) in Ghodaghodi and Nakhrod Lake respectively. Likewise, the evenness value for Ghodaghodi and Nakhrod Lake was found to be higher in the pre-monsoon season (0.95), (0.92) and lower in the monsoon season (0.79), (0.68) in Ghodaghodi and Nakhrod Lake, respectively.
‘छिमेकीको छाता र छाडा छोराहरू’ कथामा वर्गीय सीमान्तीयता
Authors: खड्का Khadka बोमबहादुर Bombahadur 
Published: January 2024

प्रस्तुत अनुसन्धानात्मक लेख महेशविक्रम शाहद्वारा लेखिएको काठमाडौँमा कामरेड (२०६८) कथासङ्ग्रहमा सङ्ग्रहीत ‘छिमेकीको छाता र छाडा छोराहरू’ कथालाई वर्गीय सीमान्तीयताको कोणबाट विश्लेषण गरिएको छ । सबाल्र्टन समालोचना सिद्धान्तले समाजमा दबिएका वा दबाइएका क्षेत्र, जाति, वर्ग, लिङ्ग, आदि व्यक्ती वा समुदायको अध्ययन गर्दछ । सबाल्टर्न शब्दको अर्थविस्तारका क्रममा सबाल्टर्नले सामाजिक, सांस्कृतिक, आर्थिक, राजनीतिक, लैङ्गिक, पेसाजस्ता हरेक हिसाबले तल परेका र पारिएका वर्ग वा समूहको अध्ययन गर्दछ । यसरी प्रस्तुत कथामा रहेका म पात्र, सात भाइ छोरहरू, छिमेकी, उँचो जमिन, समथल जमिन, बाह्रैकाल बग्ने पानीको मुहान आदि सन्दर्भकै सेरोफेरोमा लेख अगाडि बढेको छ । कथामा सामन्ती र विस्तारवादी बिचारले निर्देशित म पात्रको छिमेकी जल, थल, अन्नपात, बिज्ञान प्रविधि, धनदौलत आदिले सम्पन्नशाली भएपनि ऊ म पात्रको एक रोपनी समथल भूमि र बाह्रैकाल बग्ने पानीको श्रोतमाथि आँखा गाडि बेलाकुबेलामा बखेडा निकालेर म पात्रलाई पिरोल्छ । एक दिन छिमेकीले म पात्रलाई जग्गा उल्टोपाल्टो देखिएकाले नयाँ नापी गर्नुपर्ला जस्तो छ, भोलि नक्सा र लालपुर्जा ल्याई उसको घरमा आउन निर्देश गर्दा म पात्रलाई चिन्ता प्रारम्भ भएको छ । छिमेकीले म पात्रप्रति गरेको कुचेष्टा र आफूमा उत्पन्न भएको चिन्ताका सम्वन्धमा छिमेकीको हुण्डी खाएर ढाडिएका आफ्ना सात भाइ छोराहरूसँग एक–एक गरी राय माग्छ । तर उनीहरूले पानीको श्रोत र समथल जमिन छिमेकीलाई जिम्मा दिँदा ठिक हुँने बिचार राखेका छन्। यसरी सात भाइ छोराहरूले छिमेकीको प्रभुत्वस्वीकरण गरि उसकै पक्षमा वकालत गरि म पात्रलाई किनारीकृत गरेको देखिएकाले विवेच्य कथा वर्गीय सीमान्तकृत कथा हो भन्ने प्रष्ट देखिएको छ ।
Pengaruh Pelatihan Dan Disiplin Kerja Terhadap Kinerja Karyawan PT Saitama Stamping Indonesia Di KIIC
Authors: Rochman Akbar Saeful , Sungkono Sungkono , Karnama Maman Mulya 
Published: January 2024

The research aims to determine how training, work discipline and employee performance at PT Saitama Stamping Indonesia, determine the effect of training on employee performance and the influence of work discipline on employee performance at PT Saitama Stamping Indonesia. The method used is descriptive and verifiative with a population of 420 employees of PT Saitama Stamping Indonesia. A sample of 81 respondents was taken by the Slovin method. Analysis using SEM with the help of SmartPLS. The results showed that training was in the fairly high category, work discipline was in the high category, and employee performance was in the high category. Training has a positive and significant influence on employee performance at PT Saitama Stamping Indonesia and work discipline has a positive and significant influence on employee performance at PT Saitama Stamping Indonesia.
Keywords: Training, Work Discipline and Employee Performance.
Prestasi Kerja Pegawai Di Dinas Perhubungan Kota Medan Berdasarkan Kebutuhan Penghargaan dan Kebutuhan Sosial
Authors: Hidayat Muhammad Wahyu , Syamsuri Abd. Rasyid 
Published: January 2024

This research aims to analyze the influence of esteem needs and social needs on employee work performance in the Medan City Transportation Department. The population of this study was 301 employees of the Medan City Transportation Department. The sample in this study was 172 employees of the Medan City Transportation Department. The analytical methods used are Validity Test and Reliability Test, Classical Assumption Test, Multiple Regression Analysis, T Test, F Test and Coefficient of Determination. The research results partially prove that the need for appreciation has a positive and significant effect on employee work performance at the Medan City Transportation Service. Social needs have a positive and significant influence on the Medan City Transportation Department. Simultaneously, the research results show that the need for esteem and social needs have a positive and significant effect on the Medan City Transportation Department. The R square (R2) value shows that the coefficient of determination is 0.534, meaning that the percentage of Reward Needs (X1) and Social Needs (X2) on Job Performance is 53.4% while the rest is influenced by other variables that were not studied.
Keywords: Reward Needs, Social Needs, Work Achievement
Pentingnya Literasi Keuangan Dalam Pengambilan Keputusan Investasi Bagi Generasi Milenial
Authors: Fadjar Achmad , Rachman Andry Arifian , Ikram Syafrizal 
Published: January 2024

Not a few losses that occur due to errors in the selection of assets or investment projects by a company or individual with the original intention of obtaining profitable results in the future but in reality experiencing losses due to a lack of understanding of financial literacy. The sample in this study used millennial generation S2 Accounting students at Widyatama University graduate school as respondents. Data obtained through questionnaires and interviews with data analysis using simple linear regression. The results showed that there was an influence of financial literacy on investment decision making for the millennial generation. Based on the results of descriptive analysis, it is known that in making investment decisions it is less supported by mastery of technical analysis in making investment decisions, one of the factors causing this is because financial literacy lacks understanding of financial management including basic concepts and financial products.
Keywords: Financial Literacy, Investment Decision Making, Millennial Generation
Faktor-Faktor Yang Mempengaruhi Audit Delay Pada Kantor BPKP Di Provinsi Sumatera Utara
Authors: Silalahi Santa Lusi , Barus Sri Ulina , Hulu Ebit Mardin , Zain Jenny , Syahputra Oky 
Published: January 2024

Financial reports are said to be accurate if they are presented in a timely manner when needed by users of financial statements such as the government, investors, creditors, the public, and other parties as a basis for decision making. This study aims to test and find out whether there is an effect of company size, audit opinion, auditor reputation, and audit tenure on Audit Delay. The method in this study uses quantitative methods with the sampling technique determined by the questionnaire method using the saturated sample technique, where all the population in this study is sampled. The population in this study were all auditors at the BPKP office in North Sumatra Province. the number of samples used was 62 auditors who worked at the BPKP office in North Sumatra Province. Based on the results of the research conducted, it shows that Audit Opinion and Audit Tenure have a significant effect on Audit Delay while Company Size and Audit Reputation have no significant effect on Audit Delay.
Keywords: Audit Delay, Audit Tenure, Audit Opinion, Auditor Reputation, Company Size
Pengaruh Struktur Modal, Harga Komoditas, Dan Harga Saham Terhadap Kinerja Keuangan Perusahaan (Studi Empiris Pada Perusahaan Perkebunan Kelapa Sawit Yang Terdaftar Di Bursa Efek Indonesia Periode 2018-2022)
Authors: Asikin Bachtiar , Kusumah Wedi Rusmawan , Arnan Sendi Gusnandar 
Published: January 2024

This study aims to analyze the Effect of Capital Structure, Commodity Prices, and Stock Prices on Company Financial Performance (Empirical Study on Palm Oil Plantation Companies Listed on the Indonesia Stock Exchange for the Period 2018-2022). This study uses a quantitative descriptive approach using secondary data obtained from the company's published financial statements. The research population was conducted at oil palm plantation companies listed on the Indonesia Stock Exchange for the period 2018-2022. Based on purposive sampling, a sample of 6 companies was obtained. The results showed that capital structure and commodity prices affect the company's financial performance. While stock prices have no effect on the financial performance of oil palm plantation companies. This study provides further understanding of the factors that can affect the financial performance of oil palm plantation companies in Indonesia. The results of this study can be used as a reference for companies in making decisions related to capital structure, commodity prices, and stock prices.
Keywords: Capital Structure, Commodity Price, Stock Price, Corporate Financial Performance
Pengaruh Modal, Tingkat Pendidikan Dan Penggunaan Teknologi Pada Pendapatan UMKM Sektor Perdagangan Di Denpasar Barat
Authors: Ragapatni A.A. Sg. Istri Indira , Widhiyani Ni Luh Sari 
Published: January 2024

This research aims to obtain empirical evidence on the effect of capital, education level, and the use of technology on the income of Micro, Small and Medium Enterprises (MSMEs) in the trade sector in West Denpasar. The population of this study is all MSMEs in the trade sector in West Denpasar District with a sample of 99 MSMEs based on the slovin formula. Data collection techniques in the study were carried out by distributing questionnaires with a Likert scale of 1-5. The data analysis technique used in this study is multiple linear regression. The results of the study can prove that the variables of capital, level of education, and use of technology have a positive and significant effect on the income of MSMEs in the trading sector in West Denpasar. The implications of this research are expected to be taken into consideration and input by other MSME actors in increasing income by taking into account capital, education level, and the use of technology.
Keyword: MSMEs, capital, education, technology and income