bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive Review of Subloading Surface Model: Governing Law of Irreversible Mechanical Phenomena of Solids
Authors: Hashiguchi Koichi , Yamakawa Yuki , Anjiki Takuya , Ueno Masami 
Published: January 2024

AbstractThe constitutive equations for the irreversible mechanical phenomena, e.g. the plastic deformation and the sliding between solids with the friction have been studied over the several centuries. Especially, they have been studied for the description of the cyclic loading behaviors in the last half century in order to respond to the high developments of the mechanical, the civil and the structural industries. Then, various constitutive models for these phenomena during the cyclic loading have been proposed hitherto. In this article, the mechanical features and the advantages/disadvantages of the constitutive models which are adopted widely for mechanical design and installed into a lot of commercial software will be clarified by the critical review for the further developments of the research on the plastic deformation/sliding phenomena and the engineering design of solids and structures, since plural different models are not necessary to these ends for the analyses of identical deformation/sliding behaviors. Eventually, it will be described that the irrational formulations involved in the past formulations can be solved out thoroughly by the recent formulations of the subloading-overstress model and subloading-overstress friction model for the monotonic and cyclic loadings under the general rate of deformation/sliding from the quasi-static to the impact loadings in unified equations, disusing the rate-independent plastic/sliding constitutive models.
Adapting non-parametric spline representations of outdoor air pollution health effects associations for use in public health benefits assessment
Authors: Burnett Richard , Cork Michael , Fann Neal , Chen Hong , Weichenthal Scott 
Published: January 2024

AbstractThe magnitude and shape of the association between outdoor air pollution concentrations and health need to be characterized in order to estimate public health benefits from proposed mitigation strategies. Specialized parametric functions have been proposed for this characterization. However, non-parametric spline models offer more flexibility, less bias, and predictive power, in describing these associations and are thus preferred over relatively simple parametric formulations. Unrestricted spline representations are often reported but many are not suitable for benefits analysis due to their erratic concentration-response behavior and are usually not presented in a format consistent with the requirements necessary to conduct a benefits analysis. We propose a method to adapt non-parametric spline representations of concentration-response associations that are suitable for public health benefits analysis by transforming spline predictions and its uncertainty over the study exposure range to a new spline formulation that is both monotonically increasing and restricted to concentration-response patterns suitable for use in health benefits assessment. We selected two examples of the association between long-term exposure to fine particulate matter and mortality in Canada and the USA that displayed spline fits that were neither monotonically increasing nor suitable, we suggest, for benefits analysis. We suggest our model is suitable for benefits analysis and conduct such analyses for both Canada and the USA, comparing benefits estimates to traditional models. Finally, we provide guidance on how to report spline fitting results such they can be used either in benefits analysis directly, or to fit our new model.
Regional Therapy Approaches for Gastric Cancer with Limited Peritoneal Disease
Authors: Li Amy Y. , Sedighim Shaina , Tajik Fatemeh , Khan Aaqil M. , Radhakrishnan Vinodh K. , Dayyani Farshid , Senthil Maheswari 
Published: January 2024

Abstract
Purpose
Despite advances in systemic therapy, outcomes of patients with gastric cancer (GC) peritoneal carcinomatosis (PC) remain poor, in part because of poor penetrance of systemic therapy into peritoneal metastasis due to the plasma-peritoneal barrier and anarchic intra-tumoral circulation. Hence, regional treatment approach with administration of chemotherapy directly into the peritoneal cavity (intraperitoneal, IP) under various conditions, combined with or without cytoreductive surgery (CRS) has remained an area of significant research interest. The purpose of this review is to provide high-level evidence for regional treatment approaches in the management of GCPC with limited peritoneal disease.

Methods
A review of the current literature and ongoing clinical trials for regional IP therapies for GCPC was performed. Studies included in this review comprise of phase III randomized controlled trials, non-randomized phase II studies, high-impact retrospective studies, and active ongoing clinical trials for each available IP modality.

Results
The three common IP approaches are heated intraperitoneal chemotherapy (HIPEC), normothermic intraperitoneal chemotherapy (NIPEC) and more recently introduced, pressurized intraperitoneal aerosolized chemotherapy (PIPAC). These IP approaches have been combined with systemic therapy and/or CRS with varying degrees of promising results, demonstrating evidence of improvements in survival rates and peritoneal disease control. Patient selection, optimization of systemic therapy, and completeness of cytoreduction have emerged as major factors influencing the design of contemporary and ongoing trials.

Conclusion
IP chemotherapy has a clear role in the management of patients with GCPC, and when combined with CRS in appropriately selected patients has the potential to significantly improve survival. Ongoing and upcoming IP therapy clinical trials hold great promise to shape the treatment paradigm for GCPC.
Method Development and Optimization of Liquid-Liquid Microextraction Based on the Decomposition of Deep Eutectic Solvent for the Determination of Chromium (VI) in Spinach: Assessment of the Greenness Profile Using Eco-scale, AGREE, and AGREEprep
Authors: Moema D. , Makwakwa TA. , Nyambaka H. N. , Dube S. , Nindi MM 
Published: January 2024

AbstractA simple, effective, and ligandless liquid-liquid microextraction (LLME) procedure based on the decomposition of hydrophobic deep eutectic solvents (HDES) was developed for the separation and pre-concentration of chromium (VI) ions in spinach leaves, before the determination by flame atomic absorption spectrophotometry. In the proposed study, the first stage involved the leaching of chromium (VI) from spinach leaves with 0.1 M Na2CO3, and in the second stage, chromium (VI) extract was preconcentrated with the LLME procedure using a DES prepared from the combination of DL-menthol and formic acid as a chelating agent and extraction solvent. The DES decomposed in an aqueous donor phase resulting in the dispersion of menthol and extraction of Cr (VI) ions. Under optimal experimental conditions, the limits of detection (LOD) and quantification (LOQ) were 0.63 and 2.1 µg L−1, respectively. The relative standard deviation (RSD) was less than 7%, and the pre-concentration factor (PF) was found to be 31.25. The accuracy of the present methodology was tested by recovery experiments. The greenness of the developed method was assessed using three quantitative green metrics tools: Analytical Eco-scale, AGREE, and AGREEprep, with only Analytical Eco-scale qualifying the proposed method as green.
Antimicrobial activity and properties of de novo design of short synthetic lipopeptides
Authors: Kroneislová Gabriela , Macůrková Anna , Novotná Zuzana , Ježek Rudolf , Lovecká Petra 
Published: January 2024

AbstractThe aim of this article is to introduce the topic of newly designed peptides as well as their biological activity. We designed nine encoded peptides composed of six amino acids. All these peptides were synthesized with C-terminal amidation. To investigate the importance of increased hydrophobicity at the amino end of the peptides, all of them were subsequently synthesized with palmitic or lithocholic acid at the N-terminus. Antimicrobial activity was tested on Gram-positive and Gram-negative bacteria and fungi. Cytotoxicity was measured on HepG2 and HEK 293 T cell cultures. Peptides bearing a hydrophobic group exhibited the best antimicrobial activity. Lipopeptides with palmitic or lithocholic acid (PAL or LCA peptides) at the N-terminus and with C-terminal amidation were highly active against Gram-positive bacteria, especially against strains of Staphylococcus aureus and Candida tropicalis. The LCA peptide SHP 1.3 with the sequence LCA-LVKRAG-NH2, had high efficiency on HepG2 human liver hepatocellular carcinoma cells (97%).
Innovative therapeutic concepts for biliary tumors
Authors: Djanani Angela 
Published: January 2024

SummaryIn recent years there have been significant changes in the treatment of bile duct carcinoma. Immunotherapy has been included in first-line treatment for about a year now (IO + cisplatin/gemcitabine). Cholangiocarcinomas are genetically very heterogeneous and several new targets have been identified in recent years. These play an important role, especially in second-line treatment. This review aims to highlight the key milestones of current treatment with a focus on targeted therapy options. Especially, current data on therapeutic options such as FGFR‑2, NTRK, IDH‑1, BRAF, HER‑2 are reported.
Harnessing Cognitively Inspired Predictive Models to Improve Investment Decision-Making
Authors: Carandente Vincenzo , Sperlí Giancarlo 
Published: January 2024

AbstractIn the last years, researchers and practitioners have focused on defining portfolio optimization approaches. This task aims to identify a suitable distribution of assets for maximizing profits and minimizing risks, also offering protection against unexpected market behaviors. Nevertheless, the state-of-the-art approaches encounter significant limitations due to the complex nature of the task: (1) forecasting of non-stationary, non-linearity and volatile stock price; (2) budget allocation over different stocks satisfying multi-objective objective function; (3) risk costs can significantly affect the effectiveness of the designed approaches. In this paper, we propose a cognitively inspired framework for portfolio optimization by integrating deep learning-based stock forecasting for maximizing the revenue and portfolio diversification and Shape Ratio for minimizing the risk. Furthermore, the cognitively inspired forecasting module relies on the LSTM-based approach which combines historical financial data and technical indicators. Hence, this approach addresses the portfolio optimization task with the aim of designing more and more cognitive agents that perform autonomous actions for supporting decision-making. To make these agents cognitive, we further integrate stock forecasting into the portfolio optimization model, also investigating the main factors affecting both stock forecasting and portfolio optimization tasks. The proposed framework has been evaluated in two stages on a real-world dataset, composed of four years of information about stocks from six different areas. Firstly, we compare the proposed forecasting models based on LSTM and GRU, pointing out that the former achieves higher effectiveness results although the latter has a shorter training time. Finally, the proposed framework has been compared with different baselines, obtaining a net difference of $168 at the maximum. Finally, we compare the proposed approach w.r.t. several baselines in terms of total revenue, also providing an ablation analysis to investigate how stock prediction might support investors in dealing with portfolio optimization task.
Arbeit als sozialpädagogische Kategorie − Teil 2
Authors: Ziegler Holger 
Published: January 2024

ZusammenfassungBasierend auf dem Argument, Entfremdung markiere das zentrale sozialpädagogische Problem, kritisiert der Beitrag, dass der sozialpädagogische Theoriediskurs Arbeit als eine für (sozial)pädagogisches Denken bedeutsame Kategorie weitgehend vernachlässigt. Dem ersten Teil des Beitrag ging es um eine Klärung, was Arbeit als Kategorie meinen soll und wie sich diese zu Kategorien des Subjekts und der Problemkategorie der Entfremdung verhält. Dabei wurde die theoretische Distanz des (sozial)pädagogischen Diskurses zu Arbeit und die Engführung von Arbeit auf Lohnarbeit kritisiert. Der hier folgende zweite Teil des Beitrags problematisiert das Verständnis von Arbeit als zweckrationalem Handeln. Im Rekurs auf Überlegungen zum Gattungswesen im Anschluss an Karl Marx soll die pädagogische Bedeutung von Arbeit begründet und schließlich erörtert werden, inwiefern die Kategorie Arbeit auf Sachverhalte zutrifft, auf die sich Soziale Arbeit in ihrer Praxis richtet.
Sexual Well-Being Across the Lifespan: Is Sexual Satisfaction Related to Adjustment to Aging?
Authors: Miguel Isabel , von Humboldt Sofia , Leal Isabel 
Published: January 2024

Abstract
Introduction
Sexual satisfaction is relevant to aging well, throughout the lifespan. This study aims to compare the perspectives of sexual satisfaction and adjustment to aging (AtA) in three age cohorts across the lifespan and to analyze whether sexual satisfaction influences the perceptions of AtA.

Methods
This cross-sectional study comprised 619 participants from three different age cohorts (18–44, 45–64, and 65 + years). Three measures were used to meet the defined objectives: (a) Adjustment to Aging Scale (ATAS), (b) New Sexual Satisfaction Scale (NSSS-S), and (c) sociodemographic, health, and lifestyle questionnaire. Data were subject to MANOVAs and hierarchical regression analyses.

Results
Social support emerged as the most relevant dimension in the multifactorial nature of AtA. Generational differences were found in sense of purpose and ambitions [F(2, 616) = 14.203, p < .001], zest and spirituality [F(2, 616) = 3.175, p = .042], body and health [F(2, 616) = 8.732, p < .001], and social support [F(2, 616) = 10.646, p < .001], with participants aged 65 and older showing significantly lower levels in all dimensions. Younger participants showed the highest score for body and health. Age-related decreases in sexual satisfaction were also found, as younger participants showed statistically higher levels of sexual satisfaction, followed by middle-aged and older participants. Sexual satisfaction predicts all the dimensions of AtA, exception made for aging in place and stability. Ego-centered sexual satisfaction positively predicted sense of purpose and ambitions (β = .225, p = .015) and social support (β = .297, p < .001), while partner/sexual activity–centered sexual satisfaction was a positive predictor of zest and spirituality (β = .243, p = .010) and body and health (β = .243, p = .008).

Conclusions
Sexual satisfaction decreases with age and is positively related to dimensions of AtA. Sexual satisfaction is a relevant variable for effective approaches to promoting healthy aging and overall well-being among (older) adults.

Policy Implications
Gerontological program policies and interventions with older people would strongly benefit of including sexual satisfaction as a relevant variable for aging well along the lifespan.
Conflict Analysis Triggered by Three-Way Decision and Pythagorean Fuzzy Rough Set
Authors: Zhao Jie , Wan Renxia , Miao Duoqian 
Published: January 2024

AbstractConflict is ubiquitous in human society and has a profound impact on various fields such as the economy, politics, law, and military. Many scholars have focused on exploring the internal mechanisms and potential solutions to conflicts. Notably, describing agents’ attitudes is an effective way to construct a conflict model. However, in decision-making, agents’ attitudes on issues are often vague and ambiguous. Pythagorean fuzzy set can deal with fuzzy information more accurately than intuitionistic fuzzy set. On the basis of this understanding, we investigate the conflicts from the perspective of Pythagorean fuzzy set. Firstly, we use Pythagorean fuzzy numbers to express the attitudes of agents on issues, and subsequently establish a Pythagorean fuzzy conflict information system. Secondly, we classify agents into three categories by a pair of thresholds to establish a trisected agent set model with risk preference. Thirdly, we construct a three-way conflict analysis model based on multi-granulation Pythagorean fuzzy decision-theoretic rough set and discuss both global and local conflicts by combining conflict analysis with multi-granulation decision-theoretic rough set. Finally, we discuss the relationships and properties of the proposed conflict analysis models.
Surgical treatment strategy for thymic tumors invading the superior vena cava
Authors: Jiang Jiahao , Gao Jian , Wang Shuai , Ao Yongqiang , Song Jieqiong , Tan Lijie , Lai Hao , Ding Jianyong 
Published: January 2024

Abstract
Objective
To explore surgical treatment strategies for thymic tumors invading the superior vena cava (SVC).

Methods
Fifty-seven patients were identified to have undergone surgery at our institution for thymic tumors invading the SVC from January 2016 to June 2021. The tumors were classified based on the involvement of the SVC as follows: type I, only the left or right innominate vein involved, so the patient underwent resection only without revascularization (n = 25); type II, less than 30% of the SVC circumference involved, so the patient underwent direct resection followed by repair of the SVC defect (n = 2); and type III, more than 30% of the SVC circumference involved, so the patient underwent single conduit reconstruction between the innominate vein and right atrial appendage first followed by extended resection of the tumor and the invaded portion of the SVC (n = 30).

Results
Complete resection was achieved in all patients. Most patients (54/57) had high-risk thymoma or thymic carcinoma. No serious complications occurred in patients with type I or type II tumors. Three of the 30 patients with type III tumors died, two required repeat surgery, one experienced a myasthenia gravis crisis, and one developed a surgical site infection. The median follow-up duration was 22 months. The 5-year progression-free survival and overall survival rates were 59.6% and 81.2%, respectively.

Conclusion
This typing method can be used to guide selection of the surgical strategy for a thymic tumor involving the SVC. A strategy of single-vessel reconstruction before extensive resection is appropriate for patients with a type III tumor.
Functorial Fast-Growing Hierarchies
Authors: Aguilera J. P. , Pakhomov F. , Weiermann A. 
Published: January 2024

Abstract
We prove an isomorphism theorem between the canonical denotation systems for large natural numbers and large countable ordinal numbers, linking two fundamental concepts in Proof Theory. The first one is fast-growing hierarchies. These are sequences of functions on

$\mathbb {N}$

obtained through processes such as the ones that yield multiplication from addition, exponentiation from multiplication, etc. and represent the canonical way of speaking about large finite numbers. The second one is ordinal collapsing functions, which represent the best-known method of describing large computable ordinals.
We observe that fast-growing hierarchies can be naturally extended to functors on the categories of natural numbers and of linear orders. The isomorphism theorem asserts that the categorical extensions of binary fast-growing hierarchies to ordinals are isomorphic to denotation systems given by cardinal collapsing functions. As an application of this fact, we obtain a restatement of the subsystem

$\Pi ^1_1$

-

${\mathsf {CA_0}}$

of analysis as a higher-type well-ordering principle asserting that binary fast-growing hierarchies preserve well-foundedness.
Rarefied gas flow past a liquid droplet: interplay between internal and external flows
Authors: Bhattacharjee Rahul , Saini Sonu , Gupta Vinay Kumar , Rana Anirudh S. 
Published: January 2024

Experimental and theoretical studies on millimetre-sized droplets suggest that at low Reynolds number the difference between the drag force on a circulating water droplet and that on a rigid sphere is very small (less than 1 %) (LeClair et al., J. Atmos. Sci., vol. 29, 1972, pp. 728–740). While the drag force on a spherical liquid droplet at high viscosity ratios (of the liquid to the gas), is approximately the same as that on a rigid sphere of the same size, the other quantities of interest (e.g. the temperature) in the case of a rarefied gas flow over a liquid droplet differ from the same quantities in the case of a rarefied gas flow over a rigid sphere. The goal of this article is to study the effects of internal motion within a spherical microdroplet/nanodroplet – such that its diameter is comparable to the mean free path of the surrounding gas – on the drag force and its overall dynamics. To this end, the problem of a slow rarefied gas flowing over an incompressible liquid droplet is investigated analytically by considering the internal motion of the liquid inside the droplet and also by accounting for kinetic effects in the gas. Detailed results for different values of the Knudsen number, the ratio of the thermal conductivities and the ratio of viscosities are presented for the pressure and temperature profiles inside and outside the liquid droplet. The results for the drag force obtained in the present work are in good agreement with the theoretical and experimental results existing in the literature.
The Aristotelian Proof Revisited: A Reflection
Authors: McNabb Tyler 
Published: January 2024

AbstractMcNabb and DeVito have recently argued that Graham Oppy’s objections to the First Way are found wanting. In response, McNabb and DeVito restructured the First Way on behalf of St Thomas. More recently, Joseph Schmid and Daniel Linford argue that the restructured argument given by McNabb and DeVito is problematic, claiming that it is either valid but unmotivated or it is plainly invalid. In this paper, I argue that McNabb and DeVito’s schematic glossing of the First Way is both valid and motivated.
Self-adaptive learning particle swarm optimization-based path planning of mobile robot using 2D Lidar environment
Authors: S. Julius Fusic , R. Sitharthan 
Published: January 2024

AbstractThe loading and unloading operations of smart logistic application robots depend largely on their perception system. However, there is a paucity of study on the evaluation of Lidar maps and their SLAM algorithms in complex environment navigation system. In the proposed work, the Lidar information is finetuned using binary occupancy grid approach and implemented Improved Self-Adaptive Learning Particle Swarm Optimization (ISALPSO) algorithm for path prediction. The approach makes use of 2D Lidar mapping to determine the most efficient route for a mobile robot in logistical applications. The Hector SLAM method is used in the Robot Operating System (ROS) platform to implement mobile robot real-time location and map building, which is subsequently transformed into a binary occupancy grid. To show the path navigation findings of the proposed methodologies, a navigational model has been created in the MATLAB 2D virtual environment using 2D Lidar mapping point data. The ISALPSO algorithm adapts its parameters inertia weight, acceleration coefficients, learning coefficients, mutation factor, and swarm size, based on the performance of the generated path. In comparison to the other five PSO variants, the ISALPSO algorithm has a considerably shorter path, a quick convergence rate, and requires less time to compute the distance between the locations of transporting and unloading environments, based on the simulation results that was generated and its validation using a 2D Lidar environment. The efficiency and effectiveness of path planning for mobile robots in logistic applications are validated using Quanser hardware interfaced with 2D Lidar and operated in environment 3 using proposed algorithm for production of optimal path.