bluuebunny/crossref_metadata_2025_split huggingface dataset:
The next generation of open data platform (ODP+): use case of Qatar
Authors: Albinali Ali Ahmed , Lock Russell , Phillips Iain 
Published: December 2023

Purpose
This study aims to look at challenges that hinder small- and medium-sized enterprises (SMEs) from using open data (OD). The research gaps identified are then used to propose a next generation of OD platform (ODP+).

Design/methodology/approach
This study proposes a more effective platform for SMEs called ODP+. A proof of concept was implemented by using modern techniques and technologies, with a pilot conducted among selected SMEs and government employees to test the approach’s viability.

Findings
The findings identify current OD platforms generally, and in Gulf Cooperation Council (GCC) countries, they encounter several difficulties, including that the data sets are complex to understand and determine their potential for reuse. The application of big data analytics in mitigating the identified challenges is demonstrated through the artefacts that have been developed.

Research limitations/implications
This paper discusses several challenges that must be addressed to ensure that OD is accessible, helpful and of high quality in the future when planning and implementing OD initiatives.

Practical implications
The proposed ODP+ integrates social network data, SME data sets and government databases. It will give SMEs a platform for combining data from government agencies, third parties and social networks to carry out complex analytical scenarios or build the needed application using artificial intelligence.

Social implications
The findings promote the potential future utilisation of OD and suggest ways to give users access to knowledge and features.

Originality/value
To the best of the authors’ knowledge, no study provides extensive research about OD in Qatar or GCC. Further, the proposed ODP+ is a new platform that allows SMEs to run natural language data analytics queries.
Preoperative pulmonary nodule localization: A comparison of hook wire and Lung‐pro‐guided surgical markers
Authors: He Rui , Ming Chao , Lei Yujie , Chen Wanling , Ye Lianhua , Li Guangjian , Zhang Xiangwu , Jiang Boyi , Zeng Teng , Huang Yunchao , Zhao Guangqiang 
Published: December 2023

AbstractIn minimally invasive thoracoscopic surgery, for solitary pulmonary nodules (SPNs) far from the pleura, it is difficult to resected by only relying on imaging data, and effective preoperative localization can significantly improve the success rate of surgery. Therefore, preoperative localization is particularly important for accurate resection. Here, we compare the value of a novel Lung‐pro‐guided localization technique with Hook‐wire localization in video‐assisted thoracoscopic surgery.MethodIn this study, 70 patients who underwent CT‐guided Hook‐wire localization and Lung‐pro guided surgical marker localization before VATS‐based SPNs resection between May 2020 and March 2021 were analyzed, and the clinical efficacy and complication rate of the two groups were compared.ResultThirty‐five patients underwent Lung‐pro guided surgical marker localization, and 35 patients underwent CT‐guided Hook‐wire localization. The localization success rates were 94.3% and 88.6%, respectively (p = 0.673). Compared with the puncture group, the locating time in the Lung‐pro group was significantly shorter (p = 0.000), and the wedge resection time was slightly shorter than that in the puncture group (P = 0.035). There were no significant differences in the success rate of localization, localization complications, intraoperative blood loss, postoperative hospital stay, and the number of staplers used.ConclusionThe above studies show that the Lung‐pro guided surgical marker localization and the CT‐guided Hook‐wire localization have shown good safety and effectiveness. However, the Lung‐pro guided surgical marker localization may show more safety than the Hook‐wire and can improve the patient's perioperative experience.
Genetic diversity, gene flow, and landscape resistance in a pond‐breeding amphibian in agricultural and natural forested landscapes in Norway
Authors: Haugen Hanne , Dervo Børre K. , Østbye Kjartan , Heggenes Jan , Devineau Olivier , Linløkken Arne 
Published: December 2023

AbstractGenetic diversity is a key part of biodiversity, threatened by human activities that lead to loss of gene flow and reduction of effective population sizes. Gene flow is a result of both landscape connectivity and demographic processes determining the number of dispersing individuals in space and time. Thus, the effect of human impact on processes determining the level of genetic diversity must be interpreted in the context of basic ecological conditions affecting survival and recruitment. When the intensity of human impact and habitat suitability correlate, the effect on genetic diversity and gene flow may be challenging to predict. We compared genetic diversity, gene flow and landscape resistance in two contrasting landscapes in Norway for the pond‐breeding amphibian Triturus cristatus: a highly human‐impacted, agricultural landscape with ecologically productive habitats, and a forested landscape with less productive habitats and lower levels of human impact. Our results show that genetic diversity was higher and gene flow lower within the forested landscape. Microclimatic moisture conditions and vegetation cover were important determinants of landscape resistance to gene flow within both landscapes. There were indications that landscape resistance was increased by minor roads in the forested landscape, which was not the case for the agricultural landscape, suggesting a higher vulnerability to human interference within the landscape matrix for the populations in less productive habitats. Our findings suggest that the effect of human impact on genetic diversity may not be straightforward but modulated by the ecological conditions underlying local demographic processes. Populations within both landscapes seem to be vulnerable to loss of genetic diversity, but due to different mechanisms. This has implications for the choice of relevant management actions, that is, increasing population stability may be more relevant within an agricultural landscape still permeable for dispersal, while conserving dispersal corridors may be more appropriate in the forested landscape, to avoid isolation and increased genetic drift.
Factors related to subjective evaluation of difficulty in chewing among community‐dwelling older adults
Authors: Seto Eri , Kosaka Takayuki , Hatta Kodai , Mameno Tomoaki , Mihara Yusuke , Fushida Shuri , Murotani Yuki , Maeda Erisa , Akema Suzuna , Takahashi Toshihito , Wada Masahiro , Gondo Yasuyuki , Masui Yukie , Ishizaki Tatsuro , Kamide Kei , Kabayama Mai , Ikebe Kazunori 
Published: December 2023

AimAwareness of difficulty chewing may limit the diversity of food intake in older adults. However, few studies have clarified which factors are related to subjective difficulty in chewing. The aim was to identify factors related to subjective difficulty in chewing in 70‐ and 80‐year‐old Japanese older adults.MethodsA total of 1680 participants (792 men, 888 women) were surveyed. Difficulty in chewing was assessed with questionnaires regarding food intake, such as rice, apples, beef, and hard rice crackers. The participants were classified into two groups, the “with difficulty” group (participants who answered “cannot eat,” “can eat with difficulty,” and “can eat if small”) and the “without difficulty” group (participants who answered “can eat without problems”), according to their answers to questionnaires for each food. A logistic regression analysis with subjective difficulty in chewing as the dependent variable was performed for each food.ResultsSubjective difficulty in chewing was associated with age, occlusal force, and depression for rice; age, number of remaining teeth, occlusal force, and depression for apples; number of remaining teeth, occlusal force, and depression for beef; and number of remaining teeth and occlusal force for hard rice crackers.ConclusionsAge, number of remaining teeth, and occlusal force, as well as depression, might be related to subjective evaluation of difficulty chewing in community‐dwelling Japanese older adults. Geriatr Gerontol Int 2024; 24: 327–333.
Psychological interventions in the treatment of delusional parasitosis: a brief review
Authors: Katamanin Olivia , Jafferany Mohammad 
Published: December 2023

AbstractThis review synthesized evidence on the most up‐to‐date treatment outcomes in patients with delusional parasitosis and examined the impact of incorporating psychological interventions in conjunction with psychiatric treatment. The reporting of this review followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analysis guidelines. PubMed and Google Scholar were searched between 2013 and 2023. Nine studies were included in this review. Partial remission was observed across all cases, irrespective of the treatment approach employed. Complete remission was limited to only three studies. No correlation was observed between the incorporation of psychological intervention in conjunction with psychotropic medication and an enhanced remission outcome. The findings underscore the importance of psychotropic medication as a fundamental component in the treatment of delusional parasitosis. The results highlight that although first‐ and second‐generation psychotropic medications are the mainstay treatment options, they nevertheless play a limited role because of the patients' steadfast delusions of infestations.
Earnings inequality and the expansion of care services in the United States, 1985–2019
Authors: Gautham Leila , Folbre Nancy , Smith Kristin 
Published: December 2023

AbstractEarnings in care services are lower than in other industries, particularly among professional and managerial employees, and are more compressed than in other industries. The growth of primarily female employment in care services since the 1980s has buffered overall increases in wage inequality while slowing convergence in the gender wage differential.
Neutrophil extracellular traps in rheumatoid arthritis and periodontitis: Contribution of PADI4 gene polymorphisms
Authors: Oliveira Sicília Rezende , de Arruda José Alcides Almeida , Schneider Ayda Henriques , Bemquerer Larissa Marques , de Souza Rayssa Maria Soalheiro , Barbim Paula , de Mattos‐Pereira Gustavo Henrique , Calderaro Débora Cerqueira , Machado Caio Cavalcante , Alves Sandra Fukada , Moreira Paula Rocha , de Oliveira Renê Donizeti Ribeiro , Louzada‐Júnior Paulo , Abreu Lucas Guimarães , Cunha Fernando Queiroz , Silva Tarcília Aparecida 
Published: December 2023

AbstractAimWe sought to investigate the release of neutrophil extracellular traps (NETs) in neutrophils from individuals with rheumatoid arthritis (RA) and controls and compare the presence of NETs in gingival tissues according to periodontal status. Also, the association between single nucleotide polymorphisms (SNPs) of the peptidyl arginine deaminase type 4 (PADI4) gene and the GTG haplotype with RA, periodontitis and NETs was evaluated in vitro.Materials and MethodsPeripheral neutrophils were isolated by density gradient, and NET concentration was determined by the PicoGreen method. Immunofluorescence was studied to identify NETs by co‐localization of myeloperoxidase (MPO)‐citrullinated histone H3 (H3Cit). Genotyping for SNPs (PADI4_89; PADI4_90; PADI4_92; and PADI4_104) was performed in 87 individuals with RA and 111 controls.ResultsThe release of NETs in vitro was significantly higher in individuals with RA and periodontitis and when stimulated with Porphyromonas gingivalis. Gingival tissues from subjects with RA and periodontitis revealed increased numbers of MPO‐H3Cit‐positive cells. Individuals with the GTG haplotype showed a higher release of NETs in vitro and worse periodontal parameters.ConclusionsThe release of NETs by circulating neutrophils is associated with RA and periodontitis and is influenced by the presence of the GTG haplotype.
How Well Does Uncertainty Forecast Economic Activity?
Authors: XU JIAWEN , ROGERS JOHN 
Published: December 2023

AbstractWe evaluate the forecasting ability of several popular measures of uncertainty. We construct new real‐time versions of both macro‐economic and financial uncertainty, and analyze them together with their ex post counterparts. We find some explanatory power in all uncertainty measures, with relatively good performance by ex post macro‐economic and financial uncertainty. However, real‐time versions perform only about as well as other uncertainty measures such as economic policy uncertainty (EPU), a finding we relate to data revisions in the construction of ex post uncertainty. Real‐time data and estimation considerations are highly consequential, owing to look‐ahead bias. Real‐time uncertainty forecasts real‐time outcome variables better than it forecasts ex post revised outcome variables.
Identifying experiences of supportive care of children and young people affected by kidney failure: A qualitative systematic review
Authors: Paterson C. , Turner M. , Hooper M.‐E. , Ladbrook E. , Macauley L. , McKie A. 
Published: December 2023

AbstractBackgroundChildren and young people affected by kidney failure experience complexities in their care. Little is known about the unique needs of this young patient population group living with a long‐term condition.ObjectiveA meta‐aggregation of all qualitative studies was conducted to identify experiences of supportive care among children and young people living with kidney failure.MethodsA systematic review of qualitative studies was conducted following the Joanna Briggs Institute meta‐aggregation method. This review has been reported according to the PRISMA statement guidelines. Six electronic databases (CINAHL, Cochrane Library, MEDLINE, Proquest, PsycINFO, and Scopus) were comprehensively searched by an expert systematic review librarian using keywords and subject headings, from inception to September 2022. All studies were accessed using a predetermined inclusion and exclusion criteria. Methodological quality assessment and data extraction performed. Qualitative findings accompanied by illustrative quotes from included studies were extracted and grouped into categories which created the overall synthesised findings.ResultsA total of 34 studies were included in this review representing a total of 613 children and young people affected by kidney failure. There was a total of 190 findings which created 13 categories representing experiences of supportive care. The meta‐aggregation developed five synthesised findings namely: ‘physical needs’, ‘information and technology’, ‘treatment and healthcare’, ‘social needs’ and ‘psychological impacts’.ConclusionThis systematic review identified that children and young people affected by kidney failure can experience a range of unmet supportive care needs in routine clinical services. Kidney failure impacted children and young people's self‐identify, social and peer networks, introduced daily practical needs because of inherent physical and psychological burden due to the failure and associated treatments. Despite improvements in the medical management of kidney failure in children and young people, further attention is needed to optimise supported self‐management in this young patient group.
Use of genome‐wide DNA methylation analysis to identify prognostic CpG site markers associated with longer survival time in dogs with multicentric high‐grade B‐cell lymphoma
Authors: Teoh Yong Bin , Ishizaki Teita , Kagawa Yumiko , Yokoyama Shoko , Jelinek Jaroslav , Matsumoto Yuki , Tomiyasu Hirotaka , Tsujimoto Hajime , Takiguchi Mitsuyoshi , Yamazaki Jumpei 
Published: December 2023

AbstractBackgroundDNA methylation analysis might identify prognostic CpG sites in CHOP‐treated dogs with multicentric high‐grade B‐cell lymphoma (MHGL) with heterogenous prognosis.ObjectiveTo identify prognostic CpG sites of MHGL through genome‐wide DNA methylation analysis with pyrosequencing validation.AnimalsTest group: 24 dogs. Validation group: 100 dogs. All client‐owned dogs were diagnosed with MHGL and treated with CHOP chemotherapy.MethodsCohort study. DNA was extracted from lymph node samples obtained via FNA. Genome‐wide DNA methylation analysis using Digital Restriction Enzyme Analysis of Methylation (DREAM) was performed on the test group to identify differentially methylated CpG sites (DMCs). Bisulfite pyrosequencing was used to measure methylation status of candidate DMCs in the validation group. Median survival times (MST) were analyzed using Kaplan‐Meier (log‐rank) product limit method.ResultsDREAM analyzed 101 576 CpG sites. Hierarchical clustering of 16 262 CpG sites in test group identified group with better prognosis (MST = 55‐477 days vs 10‐301 days, P = .007). Volcano plot identified 1371 differentially methylated CpG sites (DMCs). DMC near the genes of FAM213A (DMC‐F) and PHLPP1 (DMC‐P) were selected as candidates. Bisulfite‐pyrosequencing performed on validation group showed group with methylation level of DMC‐F < 40% had favorable prognosis (MST = 11‐1072 days vs 8‐1792 days, P = .01), whereas group with the methylation level combination of DMC‐F < 40% plus DMC‐P < 10% had excellent prognosis (MST = 18‐1072 days vs 8‐1792 days, P = .009).Conclusion and Clinical ImportanceMethylation status of prognostic CpG sites delineate canine MGHL cases with longer MST, providing owners with information on expectations of potential improved treatment outcomes.
Cell death induction facilitates egress of Coxiella burnetii from infected host cells at late stages of infection
Authors: Schulze‐Luehrmann Jan , Liebler‐Tenorio Elisabeth , Felipe‐López Alfonso , Lührmann Anja 
Published: December 2023

AbstractIntracellular bacteria have evolved mechanisms to invade host cells, establish an intracellular niche that allows survival and replication, produce progeny, and exit the host cell after completion of the replication cycle to infect new target cells. Bacteria exit their host cell by (i) initiation of apoptosis, (ii) lytic cell death, and (iii) exocytosis. While bacterial egress is essential for bacterial spreading and, thus, pathogenesis, we currently lack information about egress mechanisms for the obligate intracellular pathogen C. burnetii, the causative agent of the zoonosis Q fever. Here, we demonstrate that C. burnetii inhibits host cell apoptosis early during infection, but induces and/or increases apoptosis at later stages of infection. Only at later stages of infection did we observe C. burnetii egress, which depends on previously established large bacteria‐filled vacuoles and a functional intrinsic apoptotic cascade. The released bacteria are not enclosed by a host cell membrane and can infect and replicate in new target cells. In summary, our data argue that C. burnetii egress in a non‐synchronous way at late stages of infection. Apoptosis‐induction is important for C. burnetii egress, but other pathways most likely contribute.
Emily's struggle for dignity: An idiographic case study of a woman with multiple sclerosis
Authors: Podolinská Lucia , Čáp Juraj 
Published: December 2023

AbstractDignity is one of the essential values and central concepts in nursing care. Dignity can be threatened due to radical life changes; therefore, this idiographic case study aimed to explore the sense of dignity experienced by a woman with multiple sclerosis. An interpretative phenomenological analysis was adopted, using data collected through a face‐to‐face semistructured interview with Emily, a 45‐year‐old woman. The study was approved by the local ethics committee. Six personal experiential themes were identified: To be ruled by a sick body; Silent progression; Loss of independence as a burden for the family; Will to fight for the meaning of life; Maintaining dignity‐in‐relation; Dignified care in a period of greater vulnerability. Emily's dignity is based on the effort to fight for a meaningful life, utilization of her full potential, maintain independence in activities of daily living and support in relationships. Continuous changes in functional ability, loss of self‐control and an uncertain future have a negative impact on the experience of her dignity. In the context of dignified health care, she considers individual care and maintaining autonomy important. The idiographic case study can contribute to a better understanding of the experience of a woman suffering from multiple sclerosis. It is possible to carry out interventions that aim to support her dignity, improve her quality of life and contribute to individually oriented health care.
Blood Pressure Fluctuation Pattern Associated with 90‐Day Ischemic Stroke and Transient Ischemic Attack After Total Knee Arthroplasty—A Retrospective Study
Authors: An Xiao , Zhang Yan , Li Zhirui , Song Yuxiang , Chen Jiying 
Published: December 2023

ObjectiveBlood pressure (BP) fluctuation has been demonstrated to be closely associated with stroke. However, at present, no attention is paid to the BP fluctuation following total knee arthroplasty (TKA). The aim of this study is to investigate what is BP fluctuation patterns in stroke and transient ischemic attack (TIA) patients after primary TKA, compare clinical characteristics among different BP fluctuation patterns and determine whether it could predict the occurrence of a 90‐day stroke.MethodsA retrospective study was conducted from February 1, 2011 to February 15, 2021. Stroke or TIA patients within 90 days after TKA were included. Data from a hospitalization management system were analyzed, including demographics, smoking status, comorbidities, medications, surgical variables, and 90‐day stroke, mortality, and readmission rates. BP fluctuation patterns were defined based on the average BP in the first 3 days after TKA. A logistic regression analysis model was used to identify risk factors for 90‐day stroke or TIA following TKA.ResultsOf the 1687 patients who underwent primary TKA, 4.0% (68/1687) experienced a 90‐day stroke or TIA. A total of 63 patients met the inclusion criteria, with an average age of 67.5 years and 55.6% (35/63) female. The number of stroke or TIA patients in each BP fluctuation pattern (T1–T5) was 6 (9.5%), 5 (7.9%), 4 (6.3%), 13 (20.6%), and 35 (55.6%) respectively. Patients with a T5 pattern tended to be older and had a greater reduction in average systolic blood pressure (SBP) 3 days after surgery compared to other patterns. The T5 pattern was associated with a higher occurrence of stroke and a lower occurrence of TIA. Patients with a T5 pattern also had a longer length of stay within 90 days following TKA. After adjusting for confounding factors, average SBP fluctuation ≥40 mmHg and the T5 pattern of BP fluctuation remained risk factors for 90‐day stroke or TIA after TKA.ConclusionBP fluctuation patterns in the early postoperative period are associated with 90‐day stroke and TIA following primary TKA.