bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diabetes-specific quality of life scale (DSQOL): Translation and validation of Urdu short version
Authors: Laraib Javaid  , Nasreen  Akhtar  , Iffat Batool  , Muhammad Zohaib khan  
Published: January 2024

ABSTRACT
BACKGROUND & OBJECTIVE: Quality of life has been affected by numerous psychosocial factors. Thus, for diabetic patients, it was necessary to identify the underlying factors, keeping in view the cultural norms. The objective of the current study was to validate the cultural norms of DSQOL (Diabetes-Specific Quality of Life Scale) through translation into "Urdu" language.
METHODOLOGY: A correlational research design was used in the study. Initially, the forward and backward translation method was followed to translate DSQOL. Afterward, the final Urdu translated version (20 items) was tested on a representative sample of 200 diabetic patients to establish its psychometric properties.
RESULTS: Internal consistency and correlational matrix of original, Urdu, and English scales yielded reliable results. In the main study, 200 male and female diabetic patients with an age range of 30-70 years and an average of (M±SD;45±8.25) participated. The reliability analysis showed a significant alpha coefficient for five subscales; "Social relations (α= .80), Physical complaints (α=.90), Worries about the future (α= .88), Daily hassles (α= .88), and Emotional worries (α=.87)". The item analysis of Urdu version confirmed the item total correlation of all subscales except three items. Further, CFA confirmed the factor structure of the newly translated Urdu version of DSQOL through AMOS (Analysis of Moment Structure), and the model yielded acceptable model fit indices (CFI=.90; NFI= .90). The Final Urdu version of DSQOL had 20 items.
CONCLUSION: The Urdu version of DSQOL is a valid and reliable measure for assessing the diabetics-specific quality of life. This translated tool overcame the cultural barrier with respect to language and norms.
Pensamiento Científico y el Tutor
Authors: Benavente Ramírez Eustorgio Godoy , Lecca Herculano Carlos , Susanibar Hoces Teobaldo Noreña 
Published: January 2024

El objetivo de este trabajo fue definir la relación del pensamiento científico y el tutor en los estudiantes de la Facultad de Educación de la Universidad Nacional José Faustino Sánchez Carrión. Metodología: Método deductivo, no experimental, transversal, correlacional, con una población de 300 y una muestra de 43 estudiantes. Resultados: Según el Rho de Spearman la correlación es adversa -0,197 y el nivel de significancia 0,205. Conclusión: No existe correlación entre los variables pensamiento científico y el tutor, sin embargo, hay una correlación negativa. Cuanto más se activa el pensamiento científico, menor es la participación del tutor en los estudiantes de la universidad.
Discovery of a Large-scale H i Plume in the NGC 7194 Group
Authors: Pak Mina , Baek Junhyun , Lee Joon Hyeop , Chung Aeree , Owers Matt , Jeong Hyunjin , Sung Eon-Chang , Sheen Yun-Kyeong 
Published: January 2024

Abstract
We present the discovery of a new H i structure in the NGC 7194 group from the observations using the Karl G. Jansky Very Large Array. NGC 7194 group is a nearby (z ∼ 0.027) small galaxy group with five quiescent members. The observations reveal a 200 kpc long H i plume that spans the entire group with a total mass of M
H I = 3.4 × 1010
M
⊙. The line-of-sight velocity of the H i gas gradually increases from south (7200 km s−1) to north (8200 km s−1), and the local velocity dispersion is up to 70 km s−1. The structure is not spatially coincident with any member galaxies but it shows close associations with a number of blue star-forming knots. Intragroup H i gas is not rare, but this particular structure is still one of the unusual cases in the sense that it does not show any clear connection with sizable galaxies in the group. We discuss the potential origins of this large-scale H i gas in the NGC 7194 group and its relation with the intergalactic star-forming knots. We propose that this H i feature could have originated from tidal interactions among group members or the infall of a late-type galaxy into the group. Alternatively, it might be leftover gas from flyby intruders.
Early TeV Photons of GRB 221009A Were Absorbed by the Prompt MeV Photons
Authors: Gao Duan-Yuan , Zou Yuan-Chuan 
Published: January 2024

Abstract
GRB 221009A produced the highest flux of gigaelectronvolt–teraelectronvolt (GeV–TeV) photons ever observed, allowing the construction of a detailed TeV light curve. We focus on explaining the noticeable dip in the light curve around 2–5 s after the onset of TeV emission. We propose that megaelectronvolt (MeV) photons from the prompt emission annihilate with TeV photons from the afterglow, producing an optical depth that obscures the TeV emission during this period. We develop a two-zone model accounting for the angles of MeV photons that can successfully reproduce the time delay between MeV and TeV photons, the peak optical depth over 3, and the rapid decline in optical depth. Our model supports MeV–TeV annihilation as the cause of the dip and provides reasonable constraints on the emission region parameters.
Le genre de l’autonomie temporelle
Authors: Ganault Jeanne 
Published: January 2024

De nombreux travaux rendent compte d’inégalités persistantes entre hommes et femmes salariés sur le marché du travail. Les inégalités d’autonomie temporelle, c’est-à-dire de libertés dans l’agencement de leur temps de travail rémunéré, restent en revanche méconnues. À partir des enquêtes Conditions de travail de 2013, 2016 et 2019 et de 38 entretiens réalisés entre 2019 et 2021 auprès de salariés, cet article examine les écarts d’autonomie temporelle entre femmes et hommes et leurs déterminants. Toutes choses égales par ailleurs, une femme salariée a moins de chances qu’un homme de pouvoir modifier ses horaires de travail, s’absenter librement et ne pas subir de contrôle de présence, ce qui peut venir d’un traitement différencié sur le marché du travail ou des préférences genrées antérieures à la vie professionnelle. Toutefois, même lorsque ces différences sont contrôlées, l’autonomie des hommes et des femmes salariés évolue différemment au fil des changements familiaux et professionnels. Ces derniers tendent à encourager les mères plus que les pères à prendre en charge l’articulation famille-travail, ce qui rattache à nouveau les femmes à la sphère domestique et les hommes à la sphère professionnelle.
La bourse ou la vie ?
Authors: Benvegnù Carlotta , Bernard Sophie 
Published: January 2024

La possibilité d’une autonomie temporelle permettant d’articuler les temps sociaux est l’un des premiers arguments mis en avant par Uber pour inciter à devenir chauffeur. Cette promesse est aujourd’hui mise à mal par la baisse des rémunérations, qui contraint les travailleurs à accroître leur durée de travail et à privilégier les horaires atypiques. En s’appuyant sur deux enquêtes par entretiens menées entre 2018 et 2019 à Montréal et à Paris auprès de chauffeurs Uber, l’article se propose d’analyser les stratégies d’articulation des temps sociaux qu’ils mettent en place dans ce contexte de pression économique accrue. Il met en lumière deux régimes de temporalité, correspondant à des usages différenciés de l’autonomie associée au statut d’indépendant, qui reposent sur des configurations familiales spécifiques et qui produisent des normes de parentalité divergentes. Pour la majorité des chauffeurs, le choix entre l’argent et le temps se traduit par un investissement intensif au travail, par une dégradation de leur santé et par un accroissement des inégalités de genre au sein de leur couple. Si certains parviennent encore à profiter du statut d’indépendant pour mieux articuler les temps sociaux, il ne s’agit que d’une minorité disposant de ressources spécifiques.
The Three Stages of Non-Use
Authors: Vollet Juliette , Zaffran Joël 
Published: January 2024

Le retour en formation des jeunes sans diplôme étant une priorité de la lutte contre le décrochage scolaire, il importe de comprendre pourquoi certains jeunes n’ont pas recours à un dispositif de raccrochage. Cet article défend l’idée que si le non-recours dépend des conditions sociales d’existence, le temps affecte également les représentations que les jeunes ont d’eux-mêmes et le regard qu’ils portent sur les institutions. Pour analyser cet effet, deux vagues d’entretiens ont été menées à deux années d’intervalle (janvier 2017 et décembre 2018) avec des jeunes sans diplôme. Elles ont permis de mettre en évidence trois temps du non-recours. Notre approche par les dynamiques temporelles assimile le non-recours à un processus. De plus, elle interroge les modalités de mise en œuvre de la politique publique de remédiation au décrochage scolaire.
A visually guided swim assay for mouse models of human retinal disease recapitulates the multi-luminance mobility test in humans
Authors: Hassan Salma , Hsu Ying , Mayer Sara K. , Thomas Jacintha , Kothapalli Aishwarya , Helms Megan , Baker Sheila A. , Laird Joseph G. , Bhattarai Sajag , Drack Arlene V. 
Published: January 2024

Abstract

PURPOSE:
The purpose of this study was to develop a visually guided swim assay (VGSA) for measuring vision in mouse retinal disease models comparable to the multi-luminance mobility test (MLMT) utilized in human clinical trials.

METHODS:
Three mouse retinal disease models were studied: Bardet–Biedl syndrome type 1 (Bbs1M390R/M390R
), n = 5; Bardet–Biedl syndrome type 10 (Bbs10−/−
), n = 11; and X linked retinoschisis (retinoschisin knockout; Rs1-KO), n = 5. Controls were normally-sighted mice, n = 10. Eyeless Pax6Sey-Dey
mice, n = 4, were used to determine the performance of animals without vision in VGSA.

RESULTS:
Eyeless Pax6Sey-Dey
mice had a VGSA time-to-platform (TTP) 7X longer than normally-sighted controls (P < 0.0001). Controls demonstrated no difference in their TTP in both lighting conditions; the same was true for Pax6Sey-Dey
. At 4–6 M, Rs1-KO and Bbs10−/−
had longer TTP in the dark than controls (P = 0.0156 and P = 1.23 × 10−8, respectively). At 9–11 M, both BBS models had longer TTP than controls in light and dark with times similar to Pax6Sey-Dey
(P < 0.0001), demonstrating progressive vision loss in BBS models, but not in controls nor in Rs1-KO. At 1 M, Bbs10−/−
ERG light-adapted (cone) amplitudes were nonrecordable, resulting in a floor effect. VGSA did not reach a floor until 9–11 M. ERG combined rod/cone b-wave amplitudes were nonrecordable in all three mutant groups at 9–11 M, but VGSA still showed differences in visual function. ERG values correlate non-linearly with VGSA, and VGSA measured the continual decline of vision.

CONCLUSION:
ERG is no longer a useful endpoint once the nonrecordable level is reached. VGSA differentiates between different levels of vision, different ages, and different disease models even after ERG is nonrecordable, similar to the MLMT in humans.
Potential effect of MSR1 and C6 ceramide small molecules on nasopharyngeal carcinoma based on GSEA analysis
Authors: Wen Haitao , Yang Guangrun , Guo Zhong , Fan Lixia , Chen Bowen , Zhang Dapeng , Zhou Jiafu 
Published: January 2024

Purpose: To investigate some potential therapeutic agents and targets for nasopharyngeal carcinoma (NPC).
Methods: Some potential therapeutic agents and target genes for NPC were identified by integrating bioinformatic analysis and in vitro experimental validation. Three datasets of NPC patients were gathered to reveal 26 upregulated and 344 downregulated differentially expressed genes (DGEs). Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes pathway analysis (KEGG) of the DGEs were implemented. Separately, 316 drug and small molecule target genes were acquired from the SEA database, allowing for detection of C6-ceramide as a small molecule of high relevance to NPC. Then, the differentially upregulated genes were intersected with potential target genes of C6-ceramide small molecules to obtain macrophage scavenger receptor 1 (MSR1). Finally, the study validated the potential roles of MSR1 and C6-ceramide in NPC cell lines.
Results: Knockdown of MSR1 expressions in NPC cells significantly decreased cell viability. Treatment with 10 μmol/L C6-ceramide also significantly reduced NPC cell viability (p < 0.0001). Furthermore, C6-ceramide attenuated the increase in MSR1 levels induced by MSR1 overexpression in NPC cells (p < 0.0001). Concurrently, MSR1 knockdown decreased expression of PI3K and AKT, while MSR1 overexpression upregulated AKT and PI3K levels.
Conclusion: MSR1 modulates viability of NPC cells by regulating PI3K and AKT expression. Additionally, C6-ceramide exerts therapeutic effect on NPC by regulating MSR1 expression. These findings reveal new therapeutic targets and strategies for the clinical management of NPC. These results establish a rationale for further exploration of MSR1 and ceramides as novel targets in NPC.
Analisis Strategi dan Metode Pembelajaran Bahasa Indonesia dengan Hasil Belajar Siswa di Sekolah Dasar Kelas 5
Authors: Ristiantita Monica , Sari Ainiyyah Yunita , Azahra Najwa Apriliani , Winarsih Indri Okta , Alkhoiri Muhammad Faiz , Mubarak M. Fadli , Mayarni Mayarni 
Published: January 2024

Pembelajaran Bahasa Indonesia di jenjang SD diarahkan untuk memperoleh dimensi kompetensi pemahaman, keterampilan ilmiah, dan sikap ilmiah dalam berperilaku sehari-hari saat interaksi bersama masyarakat, lingkungan, juga pemanfaatan teknologi. Dari hasil wawancara yang dilakukan kepada guru di 6 sekolah, terdapat berbagai metode pembelajaran yang diterapkan oleh Guru kepada siswanya, yaitu metode PBL, PJBL, diskusi, ceramah, role playing . Guru-guru di 6 sekolah ini di pembelajaran Bahasa Indonesia melakukan strategi berbasis empati. Penggunaan strategi berbasis empati oleh guru dalam kegiatan belajar mengajar pada kelas 5 SD sangat positif dan dapat memberikan dampak yang signifikan pada proses pembelajaran. Ketika guru mengadopsi pendekatan ini, mereka menunjukkan kepedulian terhadap kebutuhan, perasaan, dan pengalaman siswa. Tanggapan positif pertama adalah terciptanya hubungan yang lebih baik antara guru dan siswa. Dengan memahami latar belakang dan perasaan siswa, guru dapat menciptakan lingkungan belajar yang inklusif dan ramah. Dimana hal tersebut merupakan suatu strategi pembelajaran yang inovatif.
Military construction and military duty in Dagestan in 1928–1940: a historical and socio-cultural aspects
Authors: Kaymarazov G. Sh. , Kaymarazova L. G. 
Published: January 2024

The article considers the historical and socio-cultural aspects of military development in the Dagestan Autonomous Soviet Socialist Republic from 1928 to 1940, taking into account the growing interest in society and the scientific community in military history, including the problem of involving the peoples of national regions of the country in the process of formation and further development of the Soviet Armed Forces. In the research the principles of historicism, scientific objectivity, as well as comparative historical, problem-chronological, statistical and descriptive methods have been used; new publications and documentary sources that have not previously been introduced into scientific circulation have been employed.The historical and social and cultural aspects of military development in the Dagestan Autonomous Soviet Socialist Republic from 1928 to 1940 have been considered. - from the moment of the first compulsory conscription of Dagestanis for military service in the ranks of the Workers 'and Peasants' Red Army (RKKA) until the adoption in September 1939 by the Supreme Soviet of the USSR of the new Law “On General Military Duty”. This event marked the beginning of the implementation of military service by representatives of the male youth of the peoples of Dagestan service on a common basis with all nationalities of the USSR.The research characterizes the work of the authorities to establish military registration of the male part of the population and pre-conscription training of young people in a multinational region. The gender component of the process of formation of military service has been highlighted; the features of the implementation of Soviet military construction in Dagestan within the designated chronological framework identified and prospects and scope of application of the research results characterized.
Рpinciples of developing the russian cultural identity of university students in foreign language classes
Authors: Ryapolova N. V. 
Published: January 2024

Relevance. In the context of increasing geopolitical tensions in the world the development of Russian cultural identity of students in foreign language classes is of particular importance. Modern Russian society needs competent, creative and active specialists, whose training will not be relevant and sufficient without acquiring knowledge not only about the culture of the countries of the language being studied, but also about their own culture. In the current situation, a foreign language has priority importance as a means of intercultural communication and generalization of the spiritual heritage of the countries and peoples of the studied and native languages.The Research problem: what are the principles of development of Russian cultural identity that contribute to the formation of foreign language communicative competence? The purpose of the research is to substantiate the implementation of the principles of development of Russian cultural identity of technical university students in foreign language classes that contribute to the formation of foreign language communicative competence. The research methods used include pedagogical observation, study of psychological and pedagogical literature, retrospective analysis of teaching activities, assessment, study of the work experience of teachers of higher educational institutions. The results of the research are the following: the role of a foreign language in the formation of Russian cultural identity of students has been determined; principles for the development of Russian cultural identity of students in foreign language classes at a university have been formulated and examples of their implementation given. Key conclusions: the principles of ethnocultural orientation of teaching and the use of PR technologies in foreign language classes, the purpose of which is the development of the Russian cultural identity of students at a technical university, contribute to the formation of foreign language communicative competence.
Education for citizenship as a scientific problem
Authors: Putilov E. V. 
Published: January 2024

The Russian society is characterized by the process of forming a new system for educating the younger generation, the core of which is the development of an active citizenship position. The global geopolitical situation poses a whole range of tasks for the education system related to the development of new content of education based on deepening civil law education. Therefore, recently in domestic Pedagogy a certain strategic guideline has emerged for studying issues of civic-patriotic education of the younger generation.The problem of the research is to substantiate the features of education for citizenship in modern scientific and pedagogical research. Solving this problem is the goal of our research.The methodological basis of the research is based on socio-pedagogical concepts of civic education, the use of scientific methods (theoretical analysis of scientific literature, normative documents, products of teachers’ activities; descriptions; interpretation; generalizations).The research results: conceptual models of citizenship in some countries have been described; the essence of the phenomenon «Russian patriotism» has been revealed; aspects of citizenship education in modern pedagogical discourse have been outlined.Key conclusions: 1) in the scientific literature, four models of citizenship have been revealed: American, British, German and Russian; 2) the core of the concept of «citizenship» is the presence among citizens of a particular country of a number of personal qualities as personal results of educational activities; 3) the pedagogical content of citizenship is associated with the justification of this term as a subject of educational activity; highlighting the totality of civic qualities as personal results of educational activities; creation of a nurturing educational environment; teachers’ possession of the necessary competencies that allow them to carry out this work
Fourteen-day E-Cigarette Exposure Disrupts Ventilation Patterns and Serum IL-1B Levels in Adolescent Rats
Authors: Fisher Mila , Peters Alicia M. , Stokes Jennifer A. 
Published: January 2024

E-cigarettes are devices used to deliver vaporized liquids often containing nicotine and other chemicals. The purpose of this study was to investigate the effects of 14 days of e-cigarette vapor exposure in adolescent rats on lung function and inflammatory cytokine expression. Seventeen male long-evans rats were assigned to vape or air groups. The animals were exposed to either air or 5% nicotine vapor using a whole-body exposure chamber, once a day for ten minutes for fourteen consecutive days. Ventilation recordings were completed on day 0 (before exposure) and day 15 (after exposure) using unrestrained whole-body plethysmography. Both lung tissue and blood was collected for molecular assays. Baseline and post-exposure ventilation data were compared between air and vape groups across three different parameters: frequency, tidal volume, and minute ventilation. These parameters were compared resulting in three distinct 2x2 (time x treatment) Mixed Model ANOVAs. Between baseline and post-treatment measurements there was a significant decrease in values in minute ventilation (p=0.0312) and tidal volume (p=0.0031). Between treatment groups there was a significant difference in minute ventilation (p=0.0128) and frequency (p=0042). There were also significant alterations to the presence of IL-1B in the serum (p=0.0003), but not lung tissue (p=0.6525). In conclusion, following two weeks of e-cigarette vapor exposure, ventilation patterns were altered in the vapor exposed animals which decreased in tidal volume and minute ventilation suggesting possible impairment of lung function and e-cigarette exposure modified the expression of pro-inflammatory cytokine, IL-1B.