bluuebunny/crossref_metadata_2025_split huggingface dataset:
Extreme-aged patients (≥ 85 years) experience similar outcomes as younger geriatric patients following chronic subdural hematoma evacuation: a matched cohort study
Authors: Nisson Peyton L. , Francis John J. , Michel Michelot , Goel Keshav , Patil Chirag G. 
Published: January 2024

AbstractSubdural hematoma (SDH) evacuation represents one of the most frequently performed neurosurgical procedures. Several reports cite a rise in both the age and number of patient’s requiring treatment, due in part to an aging population and expanded anticoagulation use. However, limited data and conflicting conclusions exist on extreme-aged geriatric patients (≥ 85 years of age) after undergoing surgery. Patients undergoing SDH evacuation at a tertiary academic medical center between November 2013-December 2021 were retrospectively identified. The study group consisted of patients ≥ 85 years (Group 1) diagnosed with a chronic SDH surgically evacuated. A control group was created matching patients by 70–84 years of age, gender, and anticoagulation use (Group 2). Multiple metrics were evaluated between the two including length-of hospital-stay, tracheostomy/PEG placement, reoperation rate, complications, discharge location, neurological outcome at the time of discharge, and survival. A total of 130 patients were included; 65 in Group 1 and 65 in Group 2. Patient demographics, medical comorbidities, SDH characteristics, international normalized ratio, partial thromboplastin time, and use of blood thinning agents were similar between the two groups. Kaplan Meier survival analysis at one-year was 80% for Group 1 and 76% for Group 2. No significant difference was identified using the log-rank test for equality of survivor functions (p = 0.26). All measured outcomes including GCS at time of discharge, length of stay, rate of reoperations, and neurological outcome were statistically similar between the two groups. Backwards stepwise conditional logistic regression revealed no significant association between poor outcomes at the time of discharge and age. Alternatively, anticoagulation use was found to be associated with poor outcomes (OR 3.55, 95% CI 1.08–11.60; p = 0.036). Several outcome metrics and statistical analyses were used to compare patients ≥ 85 years of age to younger geriatric patients (70–84 years) in a matched cohort study. Adjusting for age group, gender, and anticoagulation use, no significant difference was found between the two groups including neurological outcome at discharge, reoperation rate, and survival.
Data-driven prediction of the surface layer state in hard-turning for optimization of component quality
Authors: Wittich Felix , Wegener Thomas , Liehr Alexander , Zinn Wolfgang , Niendorf Thomas , Kroll Andreas 
Published: January 2024

AbstractData-driven approaches are an effective solution for modeling problems in machining. To increase the service life of hard-turned components, it is important to quantify the correlation between the cutting parameters such as feed rate, cutting speed and depth of cut and the near-surface properties. For obtaining high-quality models with small data sets, different data-driven approaches are investigated in this contribution. Additionally, models that enable uncertainty quantification are crucial for effective decision-making and the adjustment of cutting parameters. Therefore, parametric multiple polynomial regression and Takagi–Sugeno models, as well as non-parametric Gaussian process regression as a Bayesian approach are considered and compared regarding their capability to predict residual stress and surface roughness values of 51CrV4 specimens after hard-turning. Moreover, a novel method based on optimization of data driven non-linear models is proposed that allows for identification of cutting parameter combinations, which at the same time lead to satisfactory surface roughness and residual stress states.
A prospective evaluation of quality of life, psychosocial distress, and functional outcomes two years after radical cystectomy and urinary diversion in 842 German bladder cancer patients
Authors: Bahlburg Henning , Reicherz Alina , Reike Moritz , Bach Peter , Butea-Bocu Marius Cristian , Tully Karl Heinrich , Roghmann Florian , Noldus Joachim , Müller Guido 
Published: January 2024

Abstract
Purpose
This study aims to evaluate survival, health-related quality of life (HRQoL), psychosocial distress, and functional outcomes after radical cystectomy (RC) and urinary diversion for ileal neobladder (INB) or ileal conduit (IC) in a contemporary German cohort of bladder cancer patients.

Methods
Patients undergoing inpatient rehabilitation after RC between April 2018 and December 2019 in one high-volume rehabilitation center were surveyed regarding HRQoL, psychosocial distress, and functional outcomes until two years after RC.

Results
Eight-hundred forty-two patients (683 male, 159 female; 395 INB, 447 IC) were included. Patients with an IC suffered more often from locally advanced disease (≥ pT3; 41.4% vs. 24.1%, p < 0.001) and lymph node metastases (19.9% vs. 11.8%, p = 0.002), resulting in worse probability of survival (p < 0.001). Global HRQoL improved steadily during follow-up, but significant differences in subscales persisted between cohorts. Multivariable regression analysis identified IC, male sex, and patient age ≤ 59 years as independent predictors for persistent high psychosocial distress. Almost 42% of female patients reported severe urinary incontinence two years after RC. Most men reported severely diminished erectile function, even after nerve-sparing surgery.

Conclusion
Global HRQoL two years after RC is comparable to the general German population. Female patients should be informed about worse continence rates. Conversely, men should be educated about erectile dysfunction. Aftercare should include psycho-oncologic counseling, especially for patients at risk.

Implications for cancer survivors
Patients should be counseled on long-term functional outcomes and persistent psychosocial distress after RC. Closer cooperation between urologists and psycho-oncologists is needed.
The burgeoning role of literature review articles in management research: an introduction and outlook
Authors: Kraus Sascha , Bouncken Ricarda B. , Yela Aránega Alba 
Published: January 2024

AbstractThis article delves into the significance and utility of literature review articles in the field of management research, encompassing their three most prominent forms: structured literature reviews, bibliometric analyses, and meta-analyses. It discusses the evolving role of literature reviews as essential tools in a research process, their methodological intricacies, and their contribution to shaping the landscape of management studies. Through a thorough examination of their merits, limitations, and best practices, our article sheds light on how literature review articles serve as valuable resources for scholars, policymakers, and practitioners in the field of management. In addition, the article points towards opportunities for using AI tools, for example Google Colab, ChatGPT, Methods Wizards, or Petal for single or multiple stages and tasks of structured literature analyses.
Fabry Disease: Cardiac Implications and Molecular Mechanisms
Authors: Weissman David , Dudek Jan , Sequeira Vasco , Maack Christoph 
Published: January 2024

Abstract
Purpose of Review
This review explores the interplay among metabolic dysfunction, oxidative stress, inflammation, and fibrosis in Fabry disease, focusing on their potential implications for cardiac involvement. We aim to discuss the biochemical processes that operate in parallel to sphingolipid accumulation and contribute to disease pathogenesis, emphasizing the importance of a comprehensive understanding of these processes.

Recent Findings
Beyond sphingolipid accumulation, emerging studies have revealed that mitochondrial dysfunction, oxidative stress, and chronic inflammation could be significant contributors to Fabry disease and cardiac involvement. These factors promote cardiac remodeling and fibrosis and may predispose Fabry patients to conduction disturbances, ventricular arrhythmias, and heart failure. While current treatments, such as enzyme replacement therapy and pharmacological chaperones, address disease progression and symptoms, their effectiveness is limited.

Summary
Our review uncovers the potential relationships among metabolic disturbances, oxidative stress, inflammation, and fibrosis in Fabry disease–related cardiac complications. Current findings suggest that beyond sphingolipid accumulation, other mechanisms may significantly contribute to disease pathogenesis. This prompts the exploration of innovative therapeutic strategies and underscores the importance of a holistic approach to understanding and managing Fabry disease.
Rapid testing in the food industry: the potential of Fourier transform near-infrared (FT-NIR) spectroscopy and spatially offset Raman spectroscopy (SORS) to detect raw material defects in hazelnuts (Corylus avellana L.)
Authors: Lösel Henri , Shakiba Navid , Bachmann René , Wenck Soeren , Le Tan Phat , Creydt Marina , Seifert Stephan , Hackl Thomas , Fischer Markus 
Published: January 2024

AbstractThe detection of raw material defects, e.g., due to incorrect or excessively long storage, is an important issue in incoming goods inspections in the food industry. Fast and easy-to-use analytical methods for evaluating the usability of raw materials are particularly important. In this study, the applicability of Fourier transform near-infrared (FT-NIR) spectroscopy and spatially offset Raman spectroscopy (SORS) for the detection of raw material defects was evaluated. For this purpose, six hazelnut batches stored at different temperatures, humidity levels, and storage times were used as examples in this pilot study. Classification models of samples before and after the different physical treatments show that the resulting changes can be detected by FT-NIR spectroscopy and SORS at elevated temperature and humidity. When one of the storage parameters is increased, FT-NIR spectroscopy is also useful for detecting differences between sample groups. In contrast, SORS cannot distinguish between pre- and post-stored samples when only one of the storage parameters is increased, making SORS unsuitable for incoming inspection of nuts. FT-NIR spectroscopy analysis is also a fast application, because freeze-drying of the sample material prior to analysis is not required as the results before and after freeze-drying are comparable. Combining the FT-NIR spectroscopy and SORS data in a low-level data fusion improved the classification models for samples stored at low storage temperatures, suggesting that the two methods provide complementary information. In summary, analyzing nuts with FT-NIR spectroscopy and SORS, as shown for hazelnuts, has the potential to identify abnormal samples during incoming goods inspections.
Carbon Footprint Evaluation in Tunnels Excavated in Rock Using Tunnel Boring Machine (TBM)
Authors: Rodríguez Rafael , Bascompta Marc , García Héctor 
Published: January 2024

AbstractThe generation of CO2 is an important element in assessing the environmental impact generated in a tunnel construction project, making this knowledge very useful for evaluating different alternatives. In this study, an analysis of the carbon footprint has been carried out, including the main elements during the construction phase of a tunnel employing a tunnel boring machine (TBM). The research proposes several options for an easy and quick calculation of CO2 generation in a design phase. Its determination can be crucial for decision-making before and during the execution of any tunnel in the near future. The estimation models have been validated based on real case studies, defining the carbon footprint of each construction element. The proposed procedure can apply to any tunnel. However, it should be noted that it is an approximate analysis, and the limitations described in each section should be considered. The main CO2 generator found in the construction process is the lining element; the percentage varies between 50% in tunnels with smaller diameters (4–5 m) and 75% for tunnels with larger diameters (9–10 m), followed by the auxiliary elements, 16%, and the operation of the tunnel boring machine itself, 11.2%, while the other parts remain in a range between 1.3 and 5.7%. This knowledge makes it possible to define the aspects on which efforts should be focussed to reduce the carbon footprint of the tunnel construction process.
Quantum Gaussian process regression for Bayesian optimization
Authors: Rapp Frederic , Roth Marco 
Published: January 2024

AbstractGaussian process regression is a well-established Bayesian machine learning method. We propose a new approach to Gaussian process regression using quantum kernels based on parameterized quantum circuits. By employing a hardware-efficient feature map and careful regularization of the Gram matrix, we demonstrate that the variance information of the resulting quantum Gaussian process can be preserved. We also show that quantum Gaussian processes can be used as a surrogate model for Bayesian optimization, a task that critically relies on the variance of the surrogate model. To demonstrate the performance of this quantum Bayesian optimization algorithm, we apply it to the hyperparameter optimization of a machine learning model which performs regression on a real-world dataset. We benchmark the quantum Bayesian optimization against its classical counterpart and show that quantum version can match its performance.
Clustering Uniswap v3 traders from their activity on multiple liquidity pools, via novel graph embeddings
Authors: Miori Deborah , Cucuringu Mihai 
Published: January 2024

AbstractUniswap is a Constant Product Market Maker built around liquidity pools, where pairs of tokens are exchanged subject to a fee that is proportional to the size of transactions. At the time of writing, there exist more than 6000 pools associated with Uniswap v3, implying that empirical investigations on the full ecosystem can easily become computationally expensive. We propose a systematic workflow to extract a tractable sub-universe of liquidity pools, where the interconnection among such pools is maximised to capture broader dynamics within the ecosystem. The resultant set of 34 pools is then used to cluster market participants according to their liquidity consumption behaviour over such environments, for the time window January–June 2022. Introducing a novel approach, we proceed to represent each liquidity taker by a suitably constructed transaction graph. The graph is a fully connected network where nodes are the liquidity taker’s executed transactions on the 34 pools of reference, and edges contain weights encoding the time elapsed between any two transactions. We then extend the NLP-inspired graph2vec algorithm to the weighted undirected setting, and employ it to obtain an embedding of the set of graphs representing market participants. This embedding allows us to extract seven clusters of liquidity takers, with equivalent behavioural patterns that can be interpreted in terms of trading attributes, i.e. preference for exotic assets over stablecoins, frequency of activity, tolerance for higher trading fees.
Trends and Characteristics of Terrorist Attacks Against Nightclub Venues Over 5 Decades
Authors: Rahman Grace R. , Liang Stephen Y. , Tian Linlin , Sin Steve S. , Jasani Gregory N. 
Published: January 2024

Abstract

Introduction:
Nightclubs are entertainment and hospitality venues historically vulnerable to terrorist attacks. This study identified and characterized terrorist attacks targeting nightclubs and discotheques documented in the Global Terrorism Database (GTD) over a 50-y period.

Methods:
A search of the Global Terrorism Database (GTD) was conducted from 1970 to 2019. Precoded variables for target type “business” and target subtype “entertainment/cultural/stadium/casino” were used to identify attacks potentially involving nightclubs. Nightclub venues were specifically identified using the search terms “club,” “nightclub,” and “discotheque.” Two authors manually reviewed each entry to confirm the appropriateness for inclusion. Descriptive statistics were performed using R (3.6.1).

Results:
A total of 114 terrorist attacks targeting nightclub venues were identified from January 1, 1970, through December 31, 2019. Seventy-four (64.9%) attacks involved nightclubs, while forty (35.1%) attacks involved discotheques. A bombing or explosion was involved in 84 (73.7%) attacks, followed by armed assault in 14 (12.3%) attacks. The highest number of attacks occurred in Western Europe and Sub-Saharan Africa. In total, 284 persons died, and 1175 persons were wounded in attacks against nightclub venues.

Conclusions:
While terrorist attacks against nightclub venues are infrequent, the risk for mass casualties and injuries can be significant, mainly when explosives and armed assaults are used.
Sex ratios and gender norms: why both are needed to understand sexual conflict in humans
Authors: Hagen Renée V. , Scelza Brooke A. 
Published: January 2024

Abstract
Sexual conflict theory has been successfully applied to predict how in non-human animal populations, sex ratios can lead to conflicting reproductive interests of females and males and affect their bargaining positions in resolving such conflicts of interests. Recently this theory has been extended to understand the resolution of sexual conflict in humans, but with mixed success. We argue that an underappreciation of the complex relationship between gender norms and sex ratios has hampered a successful understanding of sexual conflict in humans. In this paper, we review and expand upon existing theory to increase its applicability to humans, where gender norms regulate sex ratio effects on sexual conflict. Gender norms constrain who is on the marriage market and how they are valued, and may affect reproductive decision-making power. Gender norms can also directly affect sex ratios, and we hypothesize that they structure how individuals respond to market value gained or lost through biased sex ratios. Importantly, gender norms are in part a product of women's and men's sometimes conflicting reproductive interests, but these norms are also subject to other evolutionary processes. An integration of sexual conflict theory and cultural evolutionary theory is required to allow for a full understanding of sexual conflict in humans.
The Absent Dimension: Anti-Racism in Mbark Ben Zayda's Amazigh Poetics
Authors: El Guabli Brahim 
Published: January 2024

AbstractRacism is a scourge that has not spared any society or community. Moroccan society is not different in its grappling with the legacy of the complex history of slavery and racialization in North Africa. Although social scientists have dedicated much scholarly attention to the study of race in Morocco, they have not accounted for Amazigh language's rich documentation of and grappling with race and racism. Ethnographic work has emerged to explain racial dynamics between Imazighen and isuqiyn (Blacks) or Haratines, but these crucial interventions fall short of examining primary sources in Tamazight to explain how Amazigh communities negotiated racism openly in the public sphere. This article draws on the experience of the Black Amazigh poet Mbark u-Ms‘ud Ben Zayda to demonstrate that racism was not, and is not, entirely silenced in Amazigh-speaking Morocco. In fact, Amazigh sources and terminology reveal that poetic performances in this social environment have not only unsilenced racism but actively grappled with its multilayered dimensions. Adopting a close reading methodology, the article interprets portions of Ben Zayda's poetry and its response to the explicitly racializing compositions of his contemporaries.
Feasibility of a home-designed respiratory rehabilitation program for chronic obstructive pulmonary disease
Authors: Belloumi Nidhal , Habouria Chaima , Bachouch Imen , Mersni Meriem , Chermiti Fatma , Fenniche Soraya 
Published: January 2024

Abstract

Background:
According to international guidelines, respiratory rehabilitation (RR) for patients with chronic obstructive pulmonary disease (COPD) is a cornerstone of standard non-pharmacological treatment.

Aims:
To evaluate feasibility of a home-designed RR program and analyze its medium-term impact on respiratory parameters and quality of life.

Methods:
This was a prospective study involving 74 COPD patients enrolled in January 2019 and put on inhaled bronchodilator treatment associated with RR at home following a written protocol, for 16 weeks. The comparative statistical analysis highlights the difference before and after RR in terms of clinical and functional respiratory parameters as well as in terms of quality of life (assessed on the short form 36 (SF-36) questionnaire). The comparison involves RR-adherent patients versus non-adherent patients.

Results:
Mean age was 66.7 ± 8.3 years with a median of 67 years. All patients were smokers, out of which 42 patients (57%) did not quit yet. Forty-one percent of patients were frequent exacerbators. The average COPD assessment test (CAT) score in our patients was 23. The average 6-minutes walk distance (MWD) was 304 m. The BODE index in our patients was 4.11 on average. The RR program was followed by 36 patients (48%). Thirty patients (40%) applied it at least twice a week. RR-adherent patients had an average CAT score decreasing from 23 to 14.5 (P = 0.011). Their average 6-MWD was 444.6 m by the end of the study, which would be 64.2% of the calculated theoretical value. The average FEV1 increase after RR was 283 mL. The majority (69%) of RR-adherent patients were ranked as quartile 1; BODE index ≤2. The average scores of physical, psycho-social, and general dimensions assessed on the SF-36 questionnaire improved in RR-adherent patients.

Conclusions:
RR is a key non-pharmacological treatment for COPD. Its interest originates from its multidisciplinary nature, hence its effectiveness in several respiratory parameters. Our study reflects the feasibility of home-designed protocols in the absence of contraindications. We highlight also the positive impact on quality of life after RR at home.
People’s Contrasting Attitudes Towards Universal Basic Income in Sweden and South Korea
Authors: Yang Jae-jin , Choe Yonhyok , Nam Yunmin 
Published: January 2024

Abstract
The discourse on universal basic income varies widely across countries. In Sweden, public opinion is generally negative even in the context of the Covid-19 pandemic, and it is barely discussed on the public policy table. On the other hand, in South Korea, public opinion is not as negative as in Sweden, and basic income is actively raised as policy agenda. Our study based on survey results reaffirmed the contrasting attitudes of the Swedish and Suth Korean people regarding basic income and related tax increase. The basic income could appeal to the people in South Korea. On the contrary, there is little room for the introduction of basic income in Sweden. The analysis also revealed similarities within the difference. Those with high income, political-right orientation, high protection against income loss, and high tax burden would be more unfavourable toward introduction of basic income no matter which country they live in.