bluuebunny/crossref_metadata_2025_split huggingface dataset:
Yoga's effectiveness in treating prenatal depression and anxiety: a review and meta-analysis of randomized controlled trials
Authors: Tang Ying-Shu , Li Xia-Nan , Zhao Yan 
Published: October 2023

Abstract
Background
Yoga is one of the most popular physical exercises for pregnant women to relieve symptoms of prenatal depression and anxiety. Our awareness of the essential elements of a successful yoga practice during pregnancy still has inadequacies. This review will investigate the characteristics and efficacy of prenatal yoga therapies in order to give evidence on yoga-assisted therapy of pregnant depression and anxiety symptoms.
Methods
By August 2023, four English-language electronic databases had been scoured for literature of yoga therapies in pregnancy: PubMed, Embase, Cochrane Library, and Web of Science. Review Manager 5.4 software employed random-effects and fix-effects models for meta-analysis, assessing overall effects, heterogeneity, and publication bias through mean differences with 95% confidence intervals.
Results
In the beginning, 1690 studies were retrieved. After deleting duplicates, 1461 studies were examined, with 11 randomized controlled trials (RCTs) ultimately meeting the inclusion criteria. This meta-analysis found that yoga therapies during pregnancy had a substantial effect on prenatal depression (SMD = -0.75, 95%CI = -1.24 to -0.27, p = 0.002) and anxiety (SMD = -0.96, 95%CI = -1.63 to -0.29, p = 0.005). According to the findings of subgroup analysis, prenatal non-depressed pregnant women who participated in integrated yoga with a duration of every session of training > 20 minutes, more than 1 session every week, continuous training > 10 weeks, and unsupervised training improved their depression and anxiety during pregnancy.
Conclusion
Yoga during pregnancy helps to relieve symptoms of prenatal depression and anxiety and can be used as an adjunctive treatment option for prenatal depression.
The impact of prior exposure to hypoglycaemia on the inflammatory response to a subsequent hypoglycaemic episode
Authors: Verhulst Clementine E.M. , Heck Julia I. P. , Fabricius Therese W. , Stienstra Rinke , Teerenstra Steven , McCrimmon Rory J. , Tack Cees J. , Pedersen-Bjergaard Ulrik , de Galan Bastiaan 
Published: October 2023

Abstract
Background: Hypoglycaemia has been shown to induce a systemic pro-inflammatory response, which may be driven, in part, by the adrenaline response. Prior exposure to hypoglycaemia attenuates counterregulatory hormone responses to subsequent hypoglycaemia, but whether this effect can be extrapolated to the pro-inflammatory response is unclear. Therefore, we investigated the effect of antecedent hypoglycaemia on inflammatory responses to subsequent hypoglycaemia in humans.
Methods: Healthy participants (n = 32) were recruited and randomised to two 2-hour episodes of either hypoglycaemia or normoglycaemia on day 1, followed by a hyperinsulinaemic hypoglycaemic (2.8 ± 0.1 mmol/L) glucose clamp on day 2. During normoglycaemia and hypoglycaemia, and after 24 hours, 72 hours and one week, blood was drawn to determine circulating immune cell composition, phenotype and function, and 93 circulating inflammatory proteins including hs-CRP.
Results: In the group undergoing antecedent hypoglycaemia, the adrenaline response to next-day hypoglycaemia was lower compared to the control group (1.45 ± 1.24 vs 2.68 ± 1.41 nmol/l). In both groups, day 2 hypoglycaemia increased absolute numbers of circulating immune cells, of which lymphocytes and monocytes remained elevated for the whole week. Also, the proportion of pro-inflammatory CD16+-monocytes increased during hypoglycaemia. After ex vivo stimulation, monocytes released more TNF-α and IL-1β, and less IL-10 in response to hypoglycaemia, whereas levels of 19 circulating inflammatory proteins, including hs-CRP, increased for up to one week after the hypoglycaemic event. Most of the inflammatory responses were similar in the two groups, except the persistent pro-inflammatory protein changes were partly blunted in the group exposed to antecedent hypoglycaemia. We did not find a correlation between the adrenaline response and the inflammatory responses during hypoglycaemia.
Conclusion: Hypoglycaemia induces an acute and persistent pro-inflammatory response at multiple levels that occurs largely independent of prior exposure to hypoglycaemia and the release of adrenaline.
Concerning the Application of the Q Cycle to Electron Transport in Cyanobacteria
Authors: Prabhu Aadi , Cramer William 
Published: October 2023

Abstract
A working concept for the regulation of electron transport in oxygenic photosynthesis is that the electron transfer rate between the two photosystems, PSI and PSII, is governed by a ‘Q-cycle’ pathway operating in the electron transport chain which connects the two ‘reaction center’ complexes. The ‘Q-cycle’ concept was initially inferred from studies on mitochondrial electron transport. This concept has been assumed to be relevant to the electron transport pathways operating in oxygenic photosynthesis, with the majority of studies done on chloroplasts or thylakoid membranes The present study examines the existence and properties of a putative ‘Q-cycle’ in cyanobacteria. Light-induced spectral changes associated with cytochrome redox reactions in intact cells of the cyanobacterium Synechococcus sp. corresponded to the oxidation-reduction of cytochrome f. A correlated reduction of heme b6 was, however, not observed. The absence of significant cytochrome b reduction might be considered inconsistent with the set of electron transfer events associated conceptually with a ‘Q-cycle’ model of the electron transfer events in the chain. However, because heme b6 in the intact cyanobacteria is mostly reduced, it is not observable as a net electron acceptor of the plastoquinol or semiquinone formed by electron transfer from photosystem II. The redox environment of intact cyanobacteria in the dark resting state has an ambient potential sufficiently reducing that the ‘Q-cycle’ pathway for electron transport, well studied and characterized for function in isolated thylakoid membranes or chloroplasts, is not observed. This apparent quandary’ is a consequence of the reducing (negative potential) intracellular redox environment of cyanobacteria, which imposes a reduced state on the b-hemes, thereby preventing observation of their light-induced reduction.
Systematic identification of knowledge gaps in whole-genome sequence analysis of multi-resistant thermotolerant Campylobacter spp
Authors: Zarske Michael , Luu Huong Quynh , Deneke Carlus , Knüver Marie-Theres , Thieck Maja , Ha Hoang Thi Thu , Bretschneider Nancy , Ngoc Pham Thi , Huber Ingrid , Stingl Kerstin 
Published: October 2023

Abstract
Background Campylobacter spp. is the most frequent cause of bacterial food-borne gastroenteritis and a high priority antibiotic resistant bacterium according to the World Health Organization (WHO). European monitoring of thermotolerant Campylobacter spp. does not reflect the global burden of resistances already circulating within the bacterial population worldwide.
Methods We systematically compared whole genome sequencing with comprehensive phenotypic antimicrobial susceptibility, analyzing 494 thermotolerant Campylobacter poultry isolates from Vietnam and Germany. Any discrepancy was checked by repeating the wet lab and improving the dry lab part. Selected isolates were additionally analyzed via long-read Oxford Nanopore technology, leading to closed chromosomes and plasmids.
Results Overall, 22 different resistance genes and gene variants (e. g. erm(B), aph(3’)-IIIa, aph(2'')-If, catA, lnu(C), blaOXA, sat4) and point mutations in three distinct genes (gyrA, 23S rRNA, rpsL) associated with AMR were present in the Campylobacter isolates. Two AMR genes were missing in the database and one falsely associated with resistance. Bioinformatic analysis based on short-read data partly failed to identify tet(O) and aadE, when the genes were present as duplicate or homologous gene variants. Intriguingly, isolates also contained different determinants, redundantly conferring resistance to gentamicin, kanamycin, streptomycin, chloramphenicol and lincomycin. We found a novel inactive tet(W) and analysis based on assemblies from short-read data was impaired to identify full-length aad9, which was apparently phase variable. One German isolate contained a yet unexplained gentamicin resistance. GyrT86I led to a rare atypical phenotype of ciprofloxacin resistance but nalidixic acid sensitivity. Long-read sequencing revealed AMR gene localization occasionally on plasmids but mainly on the chromosome, which was frequently inconsistent with predictions from short-read sequencing. AMR genes were often organized in multidrug resistance islands (MDRI) and partially located in proximity to transposase genes, suggesting main mobilization of resistance determinants via natural transformation and transposition in Campylobacter.
Conclusions The revealed gaps of knowledge suggest consideration of frequent duplicate and mosaic genes, gene mutations leading to (transiently) truncated proteins and gene variants missing in databases. Furthermore, there is a need for deciphering yet unknown resistance mechanisms and resistance spread in thermotolerant Campylobacter that may pose a challenge to global food safety.
Space-time clustering of seismic events in Chile using ST-DBSCAN-EV algorithm
Authors: Nicolis Orietta , Delgado Luis , Peralta Billy , Diaz Mailiu , Chiodi Marcello 
Published: October 2023

Abstract

Chile is one of the most seismic countries in the world especially due to the subduction of the Nazca plate under the South America plate along the Chilean cost. Normally, the spatial distribution of seismic events tends to form spatial and temporal clusters around the main event including both precursor and aftershock events. However, it is very difficult to identify whether an event is a precursor, a main event or an aftershock. In the literature, only some large earthquakes are well described but it does not exist an automatic method to classify them. In this work, we propose a new density based clustering method, called ST- DBSCAN-EV (Space-time DBSCAN with Epsilon Variable), which allows the Epsilon parameter (the radius) to vary depending on the density of the points. The results of the ST-DBSCAN-EV are validated on three important earthquakes with magnitude greater than 8.0 Mw occurred in Chile in the last 20 years, by carrying out a series of experiments considering different combinations of parameters. A comparison with some traditional clustering techniques such as the DBSCAN, ST-DBSCAN, and the K-Means has been implemented for assessing the performance of the proposed method. Almost in all cases ST-DBSCAN-EV outperformed traditional ones by providing an F1-Score metric higher than 0.8. Finally, the results of classification are compared with a declustering method.
Use of e-modules to increase awareness and utilization of preconception care services in adolescents: a study Implementation of the technology acceptance model theory
Authors: Ani Luh Seri , Utami Ni Wayan Arya , Darmay I. G.A.Sri , Mogi I. K.A. , Mertasari Luh , Ds Ni Kadek Ayu Dwi Utami , Sumiati Luh Nyoman 
Published: October 2023

Abstract

Education about PHS with online methods through e-modules is known to be more flexible than face-to-face methods. However, the use of e-modules in raising awareness and utilization of PHS in adolescents has not been proven. This study aims to explore the role of e-modules in increasing awareness and utilization of PHS in adolescents. An exploratory qualitative study was conducted in Sidemen Karangasem District, Bali, Indonesia. Exploration of the use of e-modules in adolescents using the concept of acceptance model theory. The informants in this study were selected by a purposive method consisting of adolescents, parents of adolescents, heads of community health centers, obstetrics and gynecology specialists, and information technology experts. The criteria for included informants are willing to be interviewed and coordinated when collecting data. Data were collected by in-depth interview method at the residence of each informant. The interview was conducted for ± 30 minutes/informant. The interview data were analyzed by thematic methods. Based on the results of interviews, it was found that adolescents' perceptions of PHS are by the technology acceptance model theory. Adolescent perceptions are grouped into 4 themes, namely adolescent awareness of preconception health, intention of use, perception of use, and perceived usefulness towards the use of PHS. The sub-themes of the results of this study consist of new information, preparation for healthy pregnancy from adolescents, embarrassment to visit, negative stigma, easy service procedures, available online services, and perceptions of the benefits of prevention efforts. The preconception health e-module increases awareness and utilization of PHS for adolescents. This study suggests using e-modules to expand the reach of education about PHS in adolescents.
Structural relationship of the Social-Ecological factors and Psychological factors on Physical activity
Authors: Sabo Abdulwali , Kuan Garry , Kueh Yee Cheng 
Published: October 2023

Abstract

The present study examines the mediating effect of psychological factors in the structural relationships between social and physical environmental factors and the amount of physical activity among undergraduate students at Universiti Sains Malaysia. The sample consisted of 422 students with a mean age of 20.2 years (SD = 1.27). The majority of the students were female (69.7%) and Malay (81.3%). Standardized scales were used to measure the total amount of physical activity and all the study variables. The final SEM final had a good fit to the data: CFI = 0.968, TLI = 0.948, SRMR = 0.036, RMSEA (90%CI) = 0.046 (0.025, 0.065), RMSEA p-value = 0.609 with 11 paths relationships. Family support had a significant effect on perceived benefits and perceived barriers. The effect of friend support on physical activity was significantly mediated by perceived benefits, self-efficacy, and psychological needs satisfaction. The effect of the availability of exercise facilities on physical activity was significantly mediated by perceived benefits and psychological needs satisfaction. Furthermore, psychological needs satisfaction mediated the effect of perceived benefits, perceived barriers, and self-efficacy on physical activity. The study findings illustrated that the application of the social-ecological model and psychological factors is important in order to understand and promote positive physical activity behaviour.
Unilateral serous macular detachment and cystoid macular edema following COVID-19 vaccination: A case report
Authors: Sadr Navid Elmi , Hariri Ramyar 
Published: October 2023

Abstract
Objective
To report a case of unilateral serous macular detachment accompanying cystoid macular edema following the second dose of vaccination for COVID-19.
Methods
Case report.
Case description
: A 67-year-old male presented with progressive vision loss in his left eye, seven days after receiving the second dose of the COVID-19 vaccine (BBIBP-CorV, Sinopharm). Fundus examination and spectral domain optical coherence tomography (SD-OCT) showed serous macular detachment with cystoid macular edema in the left eye. The patient’s best-corrected visual acuity improved dramatically, and macular detachment and cystoid macular edema resolved significantly within ten days, without any treatment.
Conclusion
Transient serous macular detachment accompanying cystoid macular edema may have an association with Sinopharm COVID-19 vaccination. Despite this, vaccination against COVID-19 is strongly recommended.
Spatial distribution and determinants of limited access to drinking water and sanitation services of households in India
Authors: Roy Chandan 
Published: October 2023

Abstract

Good health and well-being require safe drinking water and improved sanitation facilities. Lack of access to drinking water and sanitation facilities poses serious health risks. There are few studies based on the NFHS-5 data in the literature. Therefore, the present study used the NFHS-5 data to investigate the spatial distribution of limited access to drinking water and sanitation facilities in India. The Stata version 14.1 software was used for statistical analysis and Arc Map 10.4 was used for spatial analysis. A binary logistic regression model was applied to investigate the association between dependent and independent variables. The prevalence of limited access to drinking water and sanitation facilities was higher in Madhya Pradesh (12.28%) and Manipur (22.65%), respectively. Besides, the spatial distribution of limited access to drinking water and sanitation facilities was spatially clustered among a few central and western Indian states. In the binary logistic regression, education, wealth index, and place of residence were significantly associated with limited drinking water and sanitation services. There is regional heterogeneity in drinking water and sanitation services. With this in mind, we suggest spatially optimized target-oriented policy measures in unprivileged areas. Improving the water distribution networks and construction of sanitation facilities is also recommended.
Caracterización multivariada de la faena en pollos para carne, criados bajo diferentes densidades de alojamiento
Authors: Gallard Eliana , Menichelli Marcela , Di Masso Ricardo , Revidatti Fernando 
Published: October 2023

El objetivo de este trabajo fue identificar y caracterizar mediante un enfoque multivariado fuentes de variancia para los caracteres productivos a la faena en pollos broiler machos y hembras criados bajo dos densidades de alojamiento. El trabajo se llevó a cabo en una granja comercial del noreste de Santa Fe, Argentina. Se alojaron 54.000 pollos Cobb500® de un día de edad en lotes mixtos, en dos galpones oscurecidos de ventilación forzada. Se ensayaron dos densidades de alojamiento: densidad estándar (14 pollos/m2 = 29.000 aves) habitualmente utilizada en la granja y densidad reducida (12 pollos/m2 = 25.
000 aves). Las aves se faenaron a los 41 días y se evaluó el peso limpio (PL), el rendimiento de la canal (RC), de pata-muslo (RPM) y de pechuga (RP) y la proporción de grasa (PG). Los datos de las cinco variables se analizaron en forma conjunta, para cada sexo por separado, con la técnica multivariada de componentes principales. Las dos primeras componentes principales (CP1 y CP2) explicaron el 79 % de la variancia total de los datos correspondientes a los machos y el 81 % de los datos de las hembras. CP1 se asoció principalmente con el peso limpio y el rendimiento de la canal y CP2 con el rendimiento de pechuga y pata-muslo y la proporción de grasa abdominal. Los pollos alojados con mayor densidad presentaron mayor rendimiento de la canal, debido, en parte, a la mayor proporción de grasa acumulada en el abdomen, como consecuencia de su crecimiento a un peso final más bajo lo que implica diferencias en el balance energético.
Cocreation to Facilitate Communication and Collaboration Between Multidisciplinary Stakeholders in eHealth Research and Development: Case Study of the CARRIER (Coronary Artery Disease: Risk Estimations and Interventions for Prevention and Early Detection) Consortium
Authors: Latuapon Elizabeth , Hochstenbach Laura , Mahr Dominik , Scheenstra Bart , Kietselaer Bas , Spreeuwenberg Marieke 
Published: October 2023

Background
Collaboration with diverse stakeholders in eHealth research is fundamental yet complex. Stakeholders from various disciplines do not “speak the same language” and have different levels of power and interest, resulting in contrasting objectives, priorities, and expectations. An approach to constructive communication and collaboration is necessary to overcome this complex dynamic. Cocreation, known in the field of eHealth most often to involve end users, may also be suitable for facilitating stakeholder engagement and alignment.

Objective
This paper provides insights into the application of cocreation, specifically in the early phases of research that focus on involving and aligning relevant stakeholders from different academic and professional backgrounds.

Methods
The case for this study was a group discussion with members of a multidisciplinary consortium that works on developing a personalized eHealth intervention for atherosclerotic cardiovascular disease. Using stakeholder mapping, health and medicine experts, big data scientists, software developers, and an innovation manager (N=8) were invited to participate. The discussion was based on a user scenario and structured according to the Six Thinking Hats of de Bono, representing 6 different types of thinking. The discussion was recorded, transcribed verbatim, and analyzed thematically with the use of ATLAS.ti software.

Results
First, informative and intuitive thinking served the preparatory purpose of familiarization with the project details and other participants. Second, positive and critical thinking constituted the body of the discussion and resulted in an in-depth conversation. Third, creative and organizational thinking were action oriented and focused on solutions and planning to safeguard future progress. The participants repeatedly reflected on various intervention-related themes, ranging from intervention content to technical functionalities and from legal requirements to implementation in practice. Moreover, project-related matters were discussed, including stakeholder management and time and budget constraints.

Conclusions
This paper demonstrates how cocreation can be of value for multidisciplinary stakeholder engagement and alignment. Based on stakeholder mapping (with whom to discuss), a dream user scenario (what to discuss), and the Six Thinking Hats of de Bono (how to discuss), the participants shared information, discussed differences, searched for solutions, and moved toward a collective approach regarding intervention development. The lessons learned may further improve the understanding of how cocreation can contribute to multidisciplinary collaboration.