bluuebunny/crossref_metadata_2025_split huggingface dataset:
Wellens’ syndrome in clinical practice
Authors: Pereverzeva K. G. , Dubova N. V. , Biryukov S. A. , Nozhov G. V. , Yakushi S. S. 
Published: October 2023

Despite the declining cardiovascular mortality, the incidence of myocardial infarction (MI) is still high, and therefore the issues of its timely diagnosis remain extremely relevant. In addition to the main diagnostic criteria and typical electrocardiographic (ECG) signs, there are many secondary patterns that suggest MI. Wellens’ syndrome (WS) is one of these ECG patterns, which indicates that the patient is at high risk of left ventricular anterior wall MI, caused by occlusion of the anterior interventricular artery (AIA) or its critical stenosis. Despite the relatively low incidence of WS, it is necessary to increase physicians’ awareness in order to prevent MI and reduce its possible negative consequences.This article presents clinical cases of WS, which show the importance of its diagnosis in the management of patients with anginal pain. The first patient is 43-year-old with a diagnosis of class III exertional angina, a history of anginal pain, and the presence of inverted T waves in V2-V3 leads. AIA stenting was performed on the 7th day of hospitalization. The second patient is 67-year-old with a similar diagnosis and history, biphasic T waves in I, aVL, V1-V3 and V5-V6 leads, deeply inverted T waves in V4. Stenting of the AIA and right coronary artery (RCA) was performed on days 5-6 after the most severe episode of anginal pain and after the anginal pain became recurrent. In both cases, WS was not diagnosed. The third patient, 57-year-old, with T wave inversion in II, III, aVF, leads ST segment elevation of less than 1 mm in lead III, minimal ST segment depression in aVL and V2-V3 leads, followed in less than 2 hours by ST segment elevation in II, III, aVF leads. In this patient, WS was diagnosed in a timely manner, urgent coronary angiography was performed, 99% RCA stenosis was detected, and RCA stenting was performed. The outcome is left ventricular inferior wall non-Q wave MI. The last cited case of WS indicates that this syndrome develops not only with AIA damage, but also with damage to other coronary arteries.
An Integrated Investigation Of Hydrocarbon Pollution In Ahoada Area, Niger Delta Region, Nigeria
Authors: Umar Hafiz Aminu , AbdulKhanan Mohd Faisal , Shiru Mohammed Sanusi , Ahmad Anuar , AbdulRahman Muhammad Zulkarnain , Md Ami Hassan 
Published: October 2023

Abstract
This study investigates hydrocarbon pollution in Ahoada community of the Niger Delta region of Nigeria. The study uses geographic information system (GIS) for mapping oil spill hotspots in the region. Resistivity method was used for delineating the extent of hydrocarbon pollution to a depth of 19.7m at Ahoada area of the region. Three categories of soil samples:impacted soil (IMS), remediated soil (RS) and control soil (CS) were collected and analyzed for the presence of BTEX, PAH, TPH, TOC and TOG. The concentrations of the samples from the IMS and RS were compared to that of the CS to determine the extent of pollution. The GIS mapping shows that the most polluted areas in the Niger Delta Region are Rivers, Bayelsa, and Delta states. Results of the geophysical images revealed contaminants presence to depths beyond 20m at some locations in the study area. The highest depth of contaminant travel was at Ukperede. Soil samples analysis showed that the range of concentrations of TPH in IMS at Oshie was 17.27 – 58.36 mg/kg; RS was 11.73 – 50.78 mg/kg which were higher than the concentrations of 0.68 mg/kg in the CS. PAH are more prevalent in Ukperede ranging from 54.56 - 77.54 mg/kg. BTEX concentrations ranged from 0.02 – 0.38 mg/kg for IMP, 0.01 – 2.7 mg/kg for RS against CS value of 0.01 mg/kg. Study revealed that there are characteristically high resistivity values in the samples which were corroborated by the findings from the resistivity survey. TOC was found to be higher in the IMS and RS than in the CS demonstrating that significant quantity of the hydrocarbon has undergone appreciable decomposition.
Pattern of macronutrients intake among type-2 diabetes mellitus (T2DM) patients in Malaysia
Authors: Md Zaleha , Ismail Noor Hassim , Tamil Azmi Mohd , Jaafar Mohd Hasni , Ismail Rosnah , Khan Nor-Ashikin Mohamed Noor , Mat-Nasir Nafiza , Razak Nurul Hafiza Ab , Abidin Najihah Zainol , Yusof Khairul Hazdi 
Published: October 2023

Abstract
Background: The incidence of type 2 diabetes mellitus (T2DM) is rising rapidly in Malaysia. Modifying dietary intake is key to both the prevention and treatment of T2DM. This study aims to investigate the pattern of macronutrient intake among T2DM patients in Malaysia. Methods: This study was carried out on adults aged between 35 and 70 years, residing in urban and rural Malaysian communities. A series of standardised questionnaires was used to assess the sociodemographic information, dietary intake and physical activity level of 15,353 respondents who provided informed consent to participate in this study. Blood sampling (finger prick test) and physical examination were performed to obtain blood glucose and anthropometric data, respectively. The Chi-square test was used to assess differences in the trends of macronutrient intake among T2DM groups.Results: The total number of participants diagnosed with T2DM in this study was 2,254. Of these, 453 (20.1%) were newly diagnosed, 1,156 (51.3%) were diagnosed for ≤ 5 years and 645 (28.6%) were diagnosed for > 5 years. The majority of the T2DM patients consumed carbohydrate and protein in the recommended proportions. Compliance with the recommended carbohydrate intake (50–65% of Total Energy Intake (TEI)) was 19.1%, 52.2% and 28.7% among the newly diagnosed, diagnosed for ≤ 5 years and diagnosed for > 5 years groups, respectively. Compliance with the recommended protein intake (10–20% of TEI) among these groups was 20.5%, 51.9% and 27.6%, respectively. Although the differences among groups were not significant, the majority of the T2DM patients consumed fat in amounts higher than the recommended proportion (> 30% of TEI).Conclusions: The pattern of dietary intake among T2DM patients in this study showed moderate consumption of carbohydrate and protein, coupled with high fat intake. Compliance with the Recommended Nutrient Intake (RNI) was satisfactory for both carbohydrate and protein but not for fat. The pattern indicated a preference for fat rather than protein when carbohydrate intake was restricted. Further research regarding the specific types of carbohydrate, protein and fat consumed is necessary to understand the effect of these macronutrients on T2DM in Malaysia. The high proportion of newly diagnosed T2DM patients (20.1%) in this study indicates that there is a lack of awareness among the general population regarding T2DM.
Determinant factors influencing chronic complications of diabetes mellitus in Dessie Referral Hospital, Northeast Ethiopia: A Case-Control study
Authors: Aragaw Yematawork , Tadese Fentaw 
Published: October 2023

Abstract
Background: Diabetes mellitus is a group of common metabolic disorders that share the phenotype of hyperglcemia, and are caused by a complex interaction of genetics and environmental factors. Diabetes mellitus produces change in the blood vessels and therefore affects almost every part of the body.
Objective: The aim of the study was to identify the key factors influencing chronic complications of Diabetes Mellitus among diabetic patients at Dessie Comprehensive and Specialized Hospital, Northeast Ethiopia, 2021.
Methods: An institution-based case control study conducted from February to June 2021 at Dessie Comprehensive and Specialized Hospital and the sample size of this study was 1:4 ratio of cases and controls with 68 cases and 272 controls and 5% non-response rate added and total sample size was 357. Both Cases and controls were selected from diabetic patients with and without chronic complications by consecutive sampling technique respectively. Data were collected through interviewer administered questionnaire and review of patient records. Binary logistic regression model was used to examine the association and all variables with p-value < 0.25 were included in the multivariable analysis. The magnitude of the association was measured by using an Odds Ratio with its 95%CI and p value<0.05. In the final model statistical significance declared at P- value < 0.05 and with 95% confidence interval of AOR.
Result: From total respondents, 68 were cases and 272 were controls, with an overall response rate of 95%. Of these respondents, 191(56.2%) males and 149 (43.8%) were females. This study found that being unmarried (AOR=4.5(2.1-9.5)), not having job (AOR=0.2(0.06-0.44)) alcohol drinking (AOR=3.8(1.9-7.6)), physical inactivity (AOR=3.1(1.5-6.4)), DM duration of above 10years (AOR=3.1(1.3-7.2)) and body mass index BMI ≥ 25kg/m2 (AOR=2.3(1.2-4.3)) were significantly associated with diabetes mellitus complications.
Conclusion: The study identified that diabetic patients were prone to chronic complications of DM due to specific independent factors like alcohol drinking, physical inactivity diabetes duration more than 10 years and overweight and obese. Our findings emphasize the need to consider these factors in preventing complications and developing targeted interventions.
Contact Stiffness Provides a Unified Frame of Reference for Understanding the Effects of Extracellular Matrix Mechanics on Cell Behaviors
Authors: Du Jing , Zhao Peng , Zhang Zhaoyi , Zheng Yang , Gao Yina , Cao Jialing , Jiang Mingwei , Jiang Yuxuan , Gao Li , Cao Yanping 
Published: October 2023

Abstract
In cell-extracellular matrix (ECM) interactions, contact mechanics theory indicates that local ECM deformation depends on both local and non-local forces imposed by cells. Here, we investigated the use of a comprehensive variable, contact stiffness (CS), to interpret cell-ECM interactions. CS defines the relationship between the local ECM deformation and the total force from a cell, integrating the effects of ECM stiffness, ECM thickness, cell adhesion area, etc. We showed that CS scaled well in the form of a power function with both YAP activity and the extent of differentiation in human mesenchymal stem cells. A CS-based motor clutch model was proposed which reveals the intrinsic cross-scale mechanism underlying ECM mechanosensing and suggests that various physical or chemical stimuli affects the reaction force from the ECM by altering the CS. The CS-based motor clutch model interprets the contributions of cell architecture evolution to stem cell differentiation and predicts the influence of a non-adjacent ECM layer on cell behaviours. These results demonstrate that the use of CS provides a quantitative predictive framework that allows researchers to address longstanding questions about the effects of cell-ECM interactions on cell behaviors.
Use of Organic Mulch to Cultivate Climate Resilient Cotton for a Sustainable Future
Authors: Hussain Iqbal , Saleem Shahid , Ullah Hafeez , Nasir Muhammad , Iqbal Muhammad Umer , Nisar Madiha , Sabir Saba , Sheer Abbas , Fatima Sidra , Khaliq Abdul , Masood Syed Ahtisham , Rauf Hafiz Abdul , Hussain Fida 
Published: October 2023

Abstract
Climate change's threat to global agriculture, especially cotton production, has led to the adoption of mulching as a mitigation strategy. Organic mulches offer environmentally friendly benefits for cotton in challenging environments. A study evaluated various organic mulches' effects on soil properties, cotton yield, and quality in a semi-arid region with limited water and high temperature fluctuations. Results showed that wheat straw, rice, and sugarcane leaves straw maintained moderate soil temperatures (27.3°C to 27.4°C), unlike the control (41.6°C). Soil pH remained stable (7.9 to 8.1), and organic mulches raised soil carbon (0.68% to 0.72% vs. 0.51% control). Nutrient availability increased, with higher nitrogen (0.045% to 0.049%), phosphorus (6.2 mg kg−1 to 6.5 mg kg−1), and potassium (89 mg kg−1 to 92 mg kg−1) compared to control (0.028%, 5.6 mg kg−1, and 71 mg kg−1). Organic matter content rose (0.77% to 0.81%) versus the control (0.51%). Weed density decreased (4 to 5 weeds m² vs. 23 weeds m² control) with mulches. Cotton height, bolls per plant, and open-boll weight increased with mulches, elevating cotton yield (2704 kg ha−1 to 2743 kg ha−1) over control (2117 kg ha−1), with consistent ginning outturn (36.62% to 37.2%). Cotton quality remained similar, while mulches reduced irrigation frequency (7 irrigations) and total amount (533 mm); control needed more (9 irrigations, 685 mm). Crop water use efficiency improved with mulches (0.50 to 0.51 kg m−3 vs. 0.30 kg m−3 control). This study highlights organic mulch's potential to enhance soil properties, nutrient availability, weed suppression, cotton yield, and water use efficiency.
Screening of potato cultivars to Tobacco Rattle Virus (TRV) in Azad Jammu and Kashmir-North East of Pakistan
Authors: Haneef Nayla , Arif Muhammad , Ali Asad , Tariq-Khan Muhammad 
Published: October 2023

Abstract
Azad Jammu and Kashmir (AJK) in the North-East of Pakistan is a leading seed potato producing area of the country. Potato cultivars that are grown commercially in AJK were screened against Tobacco rattle virus (TRV) under natural field conditions. The potato cultivars Bataina, Desiree, Fleminco, Kurado, Line A, Line B, Margrata, Pomola, Rodalph and Ronaldo were screened against TRV. Out of 10, four cultivars Bataina, Line B and Pomola and Ronaldo were found sensitive whereas cultivars Kurado, Margrata, Line A and Rodalph were moderately sensitive. Two cultivars Desiree and Fleminco were rated moderately insensitive, and none of the tested germplasm was completely insensitive to TRV-induced tuber necrosis. The effect of TRV on quantity (yield) and quality attributes of 10 potato cultivars were investigated in field experiments at district Poonch and Sudhnoti. Preliminary results revealed that plant height, number of stems per plant, numbers of tubers and weight of tubers were severely affected by soil-borne trichodorids transmitted TRV. It was concluded that both TRV and its vector were prevalent in major potato growing areas of the AJK and the existing potato germplasm has no resistance against the virus or its vector or both posing a serious threat to the potato production in the region. This is the first report of screening of potato germplasm against TRV in the region.
Experimental Evidence of a Diatropic Ring Current Occurring in the Metal Cluster [{(C5Me4H)2La}3Sn2Bi3]2–
Authors: Dehnen Stefanie , Lohse Yannick , Rienmueller Julia , Weinert Bastian , Mathew Neeshma , Günne Jörn Schmedt auf der , Weigend Florian , Franzke Yannick 
Published: October 2023

Abstract
Aromaticity, in its most widely known form, describes the phenomenon of cyclic delocalization of (4n+2)π-electrons in a planar molecule, which leads to energetic stabilization and is accompanied by a ring current flowing within the molecular plane upon exposing the molecule to a magnetic field.1–4 This concept, which has been known for organic molecules for a century, has only recently been discussed for purely metallic compounds. On the basis of quantum chemical calculations, σ-, π-, and also ϕ-aromatic compounds were identified.5–9 However, due to either such compounds’ insolubility or the lack of suitable NMR handles, this phenomenon has not yet been experimentally proven to date. Here we close this gap by providing the first experimental evidence of a ring current. Quantum chemical calculations on the novel Zintl cluster [{(C5Me4H)2La}3Sn2Bi3] 2− reveal a diatropic ring current, indicative of an aromatic behavior, caused by the interaction of the inner (Sn2Bi3)5– unit with the three [(C5Me4H)2La]+ complex fragments. It is flowing in the {Ln3Bi3} plane of this very uncommon cluster species, which is the first ternary Zintl cluster exhibiting f-block metal complex fragments on the cluster surface. Different from all studies so far, the ring current was proved experimentally by means of solid-state MAS NMR spectroscopy. In excellent agreement with the quantum chemical prediction, the 1 H chemical shifts of the protons at the (C5Me4H)− ligands that are closest to the metal cluster core are shifted to the low field. This finding was long sought for and rationalizes numerous hypotheses made for related clusters.
Hydrogeological assessment of coastal aquifers in areas of infiltration basins in southern Brazil
Authors: Berwanger Gabriela Gutterres , Reginato Pedro Antonio Roehe , Vieiro Antônio Pedro 
Published: October 2023

Abstract
The Litoral Norte of Rio Grande do Sul has seen a population increase over the years, specially suffering from the seasonality of the population in summertimes. As a consequence, there is a significant increase in the production of effluents. A technology applied in some municipalities on the Litoral Norte is the rapid infiltration basins. However, the effective implementation of the infiltration basins requires an in-depth understanding of the local hydrogeological conditions. This work aims to carry out the evaluation of the hydrogeological characteristics of free aquifers of the Coastal Aquifer System in two areas where sewage infiltration basins. The two areas were compared in order to verify differences and similarities of the hydrogeological responses between them. The data analyzed come from the database collected in situ from a Research Project developed by IGEO/IPH. Graphic analyses, statistics for geological, hydrogeological and hydrochemical evaluation were generated, finalizing the compilation of data with Conceptual Hydrogeological Models. It was observed the contamination of E. Coli, Nitrate, TDS and Sulfate according to CONAMA Resolution nº 396/2008, with alteration of Class of groundwater for E. Coli, Nitrate and TDS. It is concluded that, despite geographical differences, extension and size of sewage systems, factors such vadose zone thickness lower than 1.5 meters, low hydraulic gradient, low groundwater flow velocity, high soil permeability and small groundwater depth are factors in both areas that trigger and provide scenarios for groundwater contamination.
Deep Ensemble Learning for Rapid Large-Scale Post-Earthquake Damage Assessment---Application to 2023 Kahramanmaraş Earthquake Sequence
Authors: Soleimani-Babakamali Mohammad Hesam , Askari Mohammad , Heravi Mohammad Ali , Sisman Rafet , Attarchian Nahid , Askan Aysegul , Soleimani Rojiar , Taciroglu Ertugrul 
Published: October 2023

Abstract
Extensive impacted region and government damage surveys following the 2023 Kahramanmaraş earthquake sequence provided a unique opportunity to design and validate a rapid post-event damage assessment framework with satellite images, addressing the typical challenges (e.g., generalization to unseen areas) encountered in rapid regional assessment efforts. By analyzing images from the significantly impacted city of Antakya, we manually identified visual features and compared those with damage states in the survey. Then, an Artificial Intelligence-based framework was developed to automate segmentation and damage assessment processes for future test areas. The resulting tool, dubbed RAPID-A, is an uncertainty-aware ensemble of various deep segmentation models fed with public data released shortly after such incidents. Furthermore, the extent of the damages reported in the survey allowed us to propose and validate a strategy to identify various intensities of damage using a single model, considering the less severe damage as more uncertain. Test case studies in Gaziantep and Kahramanmaraş demonstrate that RAPID-A is generalizable, accurate, and efficient. The significance of this framework lies in its ability to assist in rapid initial damage evaluations before expert dispatch or to replace it in countries that lack the capacity to launch large-scale regional assessment programs to guide foreign support.
Hybrid Attention-Based Shifted Graph Convolutional Networks
Authors: Liu Bo , Guoping Wang , Aihua Zhang , Liu Xiaoqun , Zhiyin Han 
Published: October 2023

Abstract
[1]Aiming at the problem that the existing algorithms for recognizing human actions in videos will be affected by changes in the environment or human body posture, a mixed-domain attention channel is designed using channel attention and spatial attention mechanisms to optimize the feature data input by the network. Use the mixed attention mechanism to detect specific parts and increase the proportion in the skeleton map, thereby improving the accuracy of action recognition. Secondly, using the shift operation to replace the conventional convolution operation in the space-time convolution graph can obtain a convolution effect that is more efficient, has fewer parameters, and has a larger receptive field. This paper conducts experiments on the NTU RGB-D dataset, and the recognition accuracy of human actions on the X-Sub subset reaches 94.5%.
[1]This work was supported by the Natural Science Foundation of Hebei Province (hky22027).
AuthorResume: Liu Xiaoqun (1968-), male, Zhangjiakou, Hebei Province, professor, master director, main research interests: computer network and information security.
Bioinformatics analysis revealed the potential crosstalk genes and molecular mechanisms between intracranial aneurysms and periodontitis
Authors: Huang Jian-huang , Chen Yao , Kang Yuan-bao , Yao Zheng-jian , Song Jian-hua 
Published: October 2023

Abstract

Objectives
The risk of intracranial aneurysms (IAs) development and rupture is significantly higher in patients with periodontitis (PD), suggesting an association between the two. However, the specific mechanisms of association between these two diseases have not been fully investigated.
Materials and Methods
In this study, we downloaded IAs and PD data from the Gene Expression Omnibus. Differentially expressed genes (DEGs) were identified, and functional enrichment analysis was performed. The protein-protein interaction (PPI) network and weighted gene co-expression network analysis (WGCNA) was performed to identified key modules and key crosstalk genes. In addition, the immune cell landscape was assessed and the correlation of key crosstalk genes with each immune cell was calculated. Finally, transcription factors (TFs) regulating key crosstalk genes were explored.
Results
127 overlapping DEGs were identified and functional enrichment analysis highlighted the important role of immune reflection in the pathogenesis of IAs and PD. We identified ITGAX and COL4A2 as key crosstalk genes. In addition, the expression of multiple immune cells was significantly elevated in PDs and IAs compared to controls, and both key crosstalk genes were significantly negatively associated with Macrophages M2. Finally, GATA2 was identified as a potential key transcription factor (TF), which regulates two key crosstalk gene.
Conclusions
The present study identifies key crosstalk genes and TF in PD and IAs, providing new insights for further study of the co-pathogenesis of PD and IAs from an immune and inflammatory perspective. Also, this is the first study to report the above findings.