bluuebunny/crossref_metadata_2025_split huggingface dataset:
Fostering Students' Competencies in Sustainability in Vocational Agriculture Education in Burundi: Effects of a Participatory Integrated Planning (PIP) Module
Authors: Nyamweru Jean Claude , Ndayitwayeko Willy Marcel , Kessler Aad , Biemans Harm 
Published: January 2025

ABSTRACTDeveloping students' sustainable agriculture competencies requires the alignment of curriculum content to encompass the full complexity of the dynamics of agriculture. However, empirical evidence from sustainable agriculture research indicates that actions oriented towards fostering students' competencies are scarce. To advance understanding, this study monitored and evaluated the development of students' sustainability competencies for smallholder farming during the implementation of a Participatory Integrated Planning (PIP) module—A sustainability learning programme that elaborates on cross‐cutting issues of long‐term integrated planning, which is normally not taught. A total number of 104 students from two vocational agricultural schools (N1 = 63; N2 = 41) were involved in the PIP learning module that was implemented from April 2022 to June 2023. Survey data on the development of the students' competencies were collected at the beginning (April 2022), in‐between (December 2022) and end (June 2023) of the implementation of the PIP module. A one‐way repeated measures MANOVA test was used to evaluate the effect of the PIP module on the development of students' competencies. Findings revealed that the PIP module significantly contributed to fostering all intended competencies, including facilitator of change, leadership, innovation and creativity, planning, system thinking, stewardship, auto‐determination and interdisciplinarity. Improvement of these competencies was much higher in the earlier stage of the learning process compared to the later stage, implying that sustainability learning requires going beyond ‘business‐as‐usual’ to retain the interest of students and competencies development. Findings also revealed that competencies development levels differ depending on schools' context, implying that sustainability learning programmes should be flexible and adaptive for learning to occur in a real‐context environment. These findings have practical implications for policies related to designing and upscaling sustainability learning programmes in vocational agriculture schools.
Pathogenicity and phylogeny of Labyrinthula spp. isolated in Washington and Oregon, USA
Authors: Agnew‐Camiener M. Victoria , Eisenlord Morgan E. , Friedman Carolyn S. , Schreier Harold J. , Burge Colleen A. 
Published: January 2025

AbstractThe class Labyrinthulomycetes constitutes a multitude of species found ubiquitously in the environment, and includes pathogens of corals, hard clams, turfgrasses, and seagrasses. Labyrinthula zosterae, the causative agent of seagrass wasting disease, has been associated with declines in seagrass coverage since the 1930s. However, pathogenic and nonpathogenic Labyrinthula spp. have been isolated from seagrass tissue. These isolates are difficult to distinguish morphologically, and the diversity of isolates where seagrass wasting disease is present is often unknown. This study aimed to increase knowledge on the pathogenicity and phylogeny of Labyrinthula spp. in Washington and Oregon, USA where a high prevalence of seagrass wasting disease has been associated with eelgrass, Zostera marina, declines. We tested the pathogenicity of 14 Labyrinthula isolates and compared partial 18S rRNA gene sequences of 12 isolates to sequences from around the world through the NCBI database. We found that pathogenic isolates could be identified as Labyrinthula zosterae, while nonpathogenic isolates did not form a clade with any previously identified SSU ribotypes. These results add to the growing data on Labyrinthula and seagrass wasting disease and can improve our understanding of pathogen evolution and spread in the future.
Hindcasting Farmed Salmon Mortality to Improve Future Health and Production Outcomes
Authors: Knight Benjamin R. , Treml Eric A. , Waddington Zac , Vennell Ross , Hutson Kate S. 
Published: January 2025

ABSTRACTIntracellular, free‐floating and biofilm‐forming bacterial pathogens have been implicated in summer mortality of farmed Chinook salmon, Oncorhynchus tshawytscha, in New Zealand. A mortality event in 2022 in the Pelorus Sound, Marlborough, was linked to high water temperatures (> 18°C), and bacterial skin disease associated with Piscirickettsia spp. (=Rickettsia‐like organisms) and Tenacibaculum species. To understand the progression of infection and potential drivers of the mortality, simulation of the event was conducted using a networked susceptible, infectious and recovered (SIR) model. Parameter exploration shows that reconstruction of observed mortality rates across three affected farm sites was possible. The best SIR simulations identified plausible values for key drivers of disease, which are consistent with previously estimated disease parameter ranges for Piscirickettsia salmonis. Our modelling shows the 2022 Pelorus Sound event likely experienced spread of bacterial pathogens within healthy fish populations at salmon farm sites over a 10‐week long incubation period, before elevated mortality was observed. We show evidence that vaccine use at one site likely prevented 10% higher mortality and that an alternative site for the vaccination could have further reduced mortalities. This result highlights the importance of future vaccine developments in aquaculture and the potential to improve vaccine efficacy through considered site selection.
Disrupting neoliberalism in the academy: Normalizing loss and enfranchising student grief
Authors: Thomas‐Jackson Shera C. , Sharp Elizabeth , Bordere Tashel C. , Moonshower Madelynn 
Published: January 2025

AbstractDespite long‐standing research demonstrating the prevalence of trauma/loss and increased visibility in the recent pandemic, natural disasters, and political violence, many institutions maintaining neoliberal ideologies and practices minimize or disregard the presence and impact of loss and grief on individuals, families, and communities. This deficit in education informs pedagogical approaches and support gaps wherein students remain the forgotten mourners with missed opportunities for development around the universal human experience of loss. In contrast to the neoliberal academy, drawing on feminist, arts‐based, and trauma‐informed pedagogies, we offer a disruption to neoliberalism by encouraging a theoretical push for scholars to normalize loss in development, enfranchise grief, and promote restorative practices. We share an example featuring art paired with Human Development and Family Science content (Healing in the Arts/HITA), whereby students drew on and/or observed performance art to engage with trauma, loss, and grief. We share strategies for faculty to address trauma and loss and offer resources and support.
Expression of PCED1A in Hepatocellular Carcinoma and Colorectal Cancer and Its Relationship with Immune Infiltration: Potential as a Diagnostic Marker
Authors: Wang Meiling , Zhang Qiqi , Wang Jing 
Published: January 2025

ABSTRACTBackgroundHepatocellular carcinoma (HCC) and colorectal cancer (CRC) pose a significant threat to human health worldwide, characterized by intricate pathogenesis. A PC‐esterase domain containing 1A (PCED1A) is a critical number of the GDSL/SGNH superfamily.AimThe aim of this study is to explore the diagnostic value of PCED1A in HCC and CRC and its relationship with immune infiltration.MethodsThe Cancer Genome Atlas (TCGA) database, Gene Expression Omnibus (GEO) database, the Cancer Cell Line Encyclopedia database (CCLE), and the Human Protein Atlas (HPA) were used to detect the expression of PCED1A in tissues and cells. Cibersoft, Timer, and Xcell were used to analyze the effect of PCED1A on immune cell infiltration. The relationship between PCED1A and the immune checkpoint was analyzed. The coexpression analysis of PCED1A was conducted using the LinkedOmics database.ResultsPCED1A was increased in HCC and CRC with poor prognosis. Immunohistochemistry demonstrated that PCED1A was highly expressed in HCC and CRC compared to corresponding normal tissues. PCED1A expression was related to poor overall survival (OS) and progression‐free survival (PFS). High PCED1A expression was strongly associated with M2 macrophages, impacting HCC progression. Conversely, low PCED1A expression was closely related to Th2 cells in CRC. In addition, the checkpoint named PDCD1 showed a good correlation with PCED1A high expression group in HCC and CRC. Lastly, the PCED1A and ZNF family showed a complex and intertwined relationship through coexpression analysis on the LinkedOmics database.ConclusionPCED1A, related to tumor immune infiltration, is a promising diagnostic biomarker and a valuable therapeutic target for HCC and CRC.
Clin‐STAR Corner: Rehabilitation for Older Adults With Heart Failure
Authors: Wingood Mariana , Vincenzo Jennifer L. , Goyal Parag , Brach Jennifer S. 
Published: January 2025

ABSTRACTHeart failure is a major contributor to morbidity, mortality, and healthcare costs, especially among older adults. Despite a large body of evidence supporting the benefits of cardiac rehabilitation, less than 30% of eligible Medicare beneficiaries participate in cardiac rehabilitation. Thus, it is essential to examine alternatives, such as physical rehabilitation, a rehabilitation approach that focuses on physical activity and function. We systematically identified and summarized four key articles published between 2022 and 2024 that highlight innovations in rehabilitation with the potential of increasing utilization. These articles emphasize three areas of opportunity: (1) home‐based telerehabilitation; (2) research focused on underrepresented and underserved populations; and (3) economic evaluations. Additional research on alternative modes of cardiac or physical rehabilitation, strategies to address heart failure‐related health inequities, and implementation studies incorporating cost‐effectiveness are needed to support increased utilization of cardiac and physical rehabilitation.
Balancing boundaries: Observed parental autonomy support and psychological control in the context of parent‐adolescent interactions and adolescent depression
Authors: Wentholt Wilma G. M. , Meurs E. H. Alet , Janssen Loes H. C. , van Houtum Lisanne A. E. M. , Wever Mirjam C. M. , Tollenaar Marieke S. , Alink Lenneke R. A. , Elzinga Bernet M. 
Published: January 2025

AbstractAutonomy support (AS) and psychological control (PC) are important parenting behaviors in adolescence, with low AS and high PC relating to adolescent depression. Studies on observed levels of AS and PC in a clinical sample are lacking. The current study aimed to (1) develop a reliable coding system for parental AS and PC in parent‐adolescent interactions and gain insights into its ecological validity in a healthy control (HC) sample, and (2) disentangle observed and adolescent‐perceived parenting behaviors in relation to adolescent depression. HC adolescents (N = 80, Mage = 15.90, 63.7% girls, 91.3% White) and their parents (N = 148, Mage = 49.00, 53.4% female, 97.3% White) and adolescents with depression (current MDD/dysthymia; N = 35, Mage = 15.60, 77.1% girls, 65.7% White) and their parents (N = 62, Mage = 50.13, 56.5% female, 79.0% White) participated in three videotaped dyadic interaction tasks (problem solving, event planning, and reminiscence). Adolescents reported on their parents' behavior and their own positive and negative affect after each task, while observed AS and PC were coded from the videos. Multilevel analyses showed that observed AS and PC, coded with our reliable system, related to adolescent‐perceived parenting (in daily life), confirming ecological validity. Adolescents with depression (vs. HC) had more negative perceptions of parenting, whereas observed AS and PC did not differ, indicating a negativity bias of adolescents with depression. Lastly, observed PC related to a lower affective state in adolescents with depression, but not HC. Parents could be psycho‐educated on the impact of this behavior in a clinical setting.
Immune‐Mediated Liver Injury From Checkpoint Inhibitor: An Evolving Frontier With Emerging Challenges
Authors: Dara Lily , De Martin Eleonora 
Published: January 2025

ABSTRACTOver the past decade, immune checkpoint inhibitors (ICIs) have transformed the treatment of cancer, though they come with the risk of immune‐related adverse (irAEs) events such as hepatotoxicity or Immune‐mediated Liver Injury from Checkpoint Inhibitors (ILICI). ILICI is a serious irAE that, when severe, requires cessation of ICI and initiation of immunosuppression. Cytotoxic T Lymphocytes (CTLs) play a central role in ILICI; however, they are just part of the picture as immunotherapy broadly impacts all aspects of the immune microenvironment and can directly and indirectly activate innate and adaptive immune cells. Clinically, as our understanding of this entity grows, we encounter new challenges. The presentation of ILICI is heterogeneous with respect to latency, pattern of injury (hepatitis vs. cholangitis) and severity. This review focuses on our knowledge regarding risk factors, presentation and treatment of ILICI including ILICI refractory to steroids. An emerging topic, the possibility of rechallenge while accepting some risk, in patients who experience ILICI but require immunotherapy, is also discussed. This review provides an update on the current knowns and unknowns in ILICI and highlights several knowledge gaps where studies are needed.
Characterisation of riverine mosquito (Diptera: Culicidae) community structure in southern Australia and the impact of a major flood based on analysis of a 20‐year dataset
Authors: Fricker Stephen R. , Keppel Gunnar , Williams Craig R. 
Published: January 2025

AbstractWe investigated the mosquito community along 315 km of the Murray River, where we identified three assemblages (upper, middle, and lower river) that exhibited different patterns of species richness and diversity over 20 years. In the lower reaches (i.e., more southern latitudes), species richness and community diversity declined over time, while there was no significant change in either the middle or upper reaches. While the overall mean abundance of the common, pathogen‐carrying mosquito (Diptera: Culicidae) species Aedes camptorhynchus Thomson, increased in the lower river but declined in the upper river. These results provide important information on the diversity and abundance of mosquito communities adjacent to the Murray River and highlight the importance of considering spatial and temporal variation when assessing the risk of mosquito‐borne diseases. Furthermore, data presented here illustrate that there the common public narrative around increasing mosquito abundance and geographic expansion under climate change is not universally true.
In Vivo Tissue Temperature Characteristics of Contact Force Catheter With a Mesh‐Shaped Irrigation Tip: A Porcine Study
Authors: Sawada Masanaru , Otsuka Naoto , Nagashima Koichi , Watanabe Ryuta , Wakamatsu Yuji , Hayashida Satoshi , Hirata Shu , Hirata Moyuru , Kurokawa Sayaka , Okumura Yasuo , Uto Kenta , Hao Hiroyuki , Takahashi Rie , Taniguchi Yoshiki 
Published: January 2025

ABSTRACTBackgroundNeither the actual in vivo tissue temperatures reached with a novel contact force sensing catheter with a mesh‐shaped irrigation tip (TactiFlex SE, Abbott) nor the safety profile has been elucidated.MethodsIn a porcine model (n = 8), thermocouples were implanted epicardially in the superior vena cava, right pulmonary vein, and esophagus close to the inferior vena cava following a right thoracotomy. After chest closure, endocardial ablation was conducted near the thermocouples under fluoroscopic guidance. We compared tissue temperatures during 50 W/13‐s high‐power short‐duration (HPSD) and 30 W/30‐s standard ablation.ResultsNo steam pops were observed in 34 HPSD and 35 standard ablation applications. Tmax (maximum tissue temperature when the thermocouple was located ≤5 mm from the catheter tip) was modestly higher in HPSD compared to standard ablation (60.1°C ± 12.4°C vs. 57.8°C ± 12.9°C; p = 0.46). The peak tissue temperature correlated inversely with the catheter tip‐to‐thermocouple distance (HPSD: r = −0.40; standard: r = −0.57). Lethal temperatures (≥50°C) were reached faster with HPSD (6.5 ± 3.2 s vs. 10.3 ± 8.6 s; p = 0.04) and the distance from the catheter tip achieving a lethal tissue temperature ≥50°C (indicative of the lesion depth) was slightly shallower with HPSD (4.2 and 4.8 mm, respectively). The esophageal injury occurred superficially in both settings (0.98 ± 0.22 mm vs. 1.16 ± 0.18 mm; p = 0.29).ConclusionsHPSD ablation produced a modestly higher and more rapid increase in the tissue temperature around the veno‐atrial junction with a shorter catheter tip‐to‐thermocouple distance required to reach lethal temperatures. This data contributes to understanding effective lesion creation and collateral injury prevention with the TactiFlex catheter.
Climate Change and Human Mobility: Considering Context, Mechanisms, and Selectivity
Authors: Garip Filiz , Reed Cody A. 
Published: January 2025

AbstractClimate change is projected to increase human mobility. Research links climate stressors, such as warming temperatures, severe weather events, and rising sea levels, to human migration within and between countries in many regions of the world. This paper reviews this new frontier for migration research and charts directions for future work. Understanding climate mobility, we argue, requires considering local context to identify mechanisms (what climate impacts) and selectivity (who responds). Research needs to draw more on existing theory to deduce selectivity patterns under alternative drivers of mobility and to extend the theory by considering how those patterns shift under climate shocks. Research also needs to generalize from diverse findings by documenting which mechanisms and selectivity patterns are most common in which contexts.
Personalized Photoprotection: Expert Consensus and Recommendations From a Delphi Study Among Dermatologists
Authors: de Troya‐Martín Magdalena , Rodríguez‐Martínez Alba , Rivas‐Ruiz Francisco , Subert Andras , Arellano‐Mendoza Maria‐Ivonne , Calzavara‐Pinton Piergiacomo , de Gálvez Maria Victoria , Gilaberte Yolanda , Goh Chee‐Leok , Lim Henry W. , Schalka Sergio , Wolf Peter , González Salvador 
Published: January 2025

ABSTRACTBackgroundRecommending comprehensive personalized photoprotection requires an accurate assessment of the patient's skin, including phototype, lifestyle, exposure conditions, environmental factors, and concomitant cutaneous conditions as well as deep knowledge of the available options: sunscreen ingredients (type of filters, spectrum coverage, sun protection factor, enhanced active ingredients), oral photoprotection, and other methods of sun protection and avoidance.ObjectivesTo establish consensus‐based recommendations endorsed by an international panel of experts for personalized medical photoprotection recommendations that are applicable globally.MethodsA two‐round Delphi study was designed to determine the degree of agreement and relevance of aspects related to personalized medical photoprotection. Items with ≥ 80% agreement and relevance were considered approved.ResultsA list of 28 recommendations for personalized medical photoprotection was approved by a panel of dermatology professionals from seven different countries. Recommendations were categorized as: (1) updated perspectives in photoprotection, (2) clinical management, (3) skin cancer prevention, (4) dark skin phototypes and skin prone to hyperpigmentation, and (5) age and lifestyle.ConclusionThis study established recommendations for the implementation of personalized medical photoprotection worldwide, highlighting areas needing further scientific and clinical evidence.
Moral disagreements: Unearthing pathways to constructive and destructive behavioral responses
Authors: Khati Bhakti , Kutlaca Maja , McPhetres Jonathon , Paolini Stefania 
Published: January 2025

AbstractIssues like transgender rights often provoke strong emotional reactions, leading to polarized conflicts. Moral psychology suggests that emotions like anger and disgust drive destructive behaviors, such as avoiding or insulting the opponent. However, we argue that constructive behaviors, such as listening to the opponent, are also possible. We propose that appraisals related to engaging and coping with moral disagreements also play critical roles in predicting different behaviors. In an online study with 902 participants from the UK, US, India, and Serbia, we explored these dynamics using a message exchange paradigm. Participants received a message, purportedly from another participant (“messenger”), that contradicted their attitudes toward transgender rights. They then provided emotional reactions, wrote a response, and indicated their willingness to engage in constructive or destructive behaviors with the messenger. Constructive behavioral intentions were predicted by greater empathy, lower disgust and anger toward the messenger, and a higher perceived ability to cope with responding. In contrast, destructive intentions were predicted by lower empathy, greater disgust, lower coping abilities, and higher perceived difficulty in responding. These findings enhance our understanding of behavioral responses to moral disagreements on contentious issues like transgender rights and suggest ways to promote constructive dialogue.
Perception and Mobilization of “Truth”: January 6, 2021, Stop the Steal, and Social Media
Authors: Hoffman Lindsay H. , Leslie Winston , Ifeanyichukwu Ebuka 
Published: January 2025

ABSTRACTIn 2021, the “Stop the Steal” movement was intensely popular among conservative and far‐right groups in the United States. It was largely predicated on the belief that the 2020 presidential election had been stolen from President Trump. While there was no concrete evidence to support that notion, an intense mobilization effort occurred, which eventually led to a deadly riot at the United States Capitol Building on January 6, 2021. Proponents of the “Stop the Steal” movement often utilized social media to promote unfounded claims of electoral fraud and irregularities in the 2020 presidential election. The present study is a content analysis of nearly 1500 tweets that appeared on political and opinion leaders’ feeds from the 2020 election through January 6, 2021. Results demonstrated that there was a high level of association between tweets on X (formerly known as Twitter) that mentioned the election and those containing electoral misinformation. There was also a moderate correlation between tweets containing calls to action and violent rhetoric regarding the election. Further, tweets that contained electoral misinformation and those that mentioned the election received significant engagement. Practical and theoretical implications are discussed.