bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cross-Cultural Adaptation and Spanish Validation of the Computerized Information Processing Assessment Battery (COGNITO)
Authors: Revert-Alcántara Nieves , Funes-Molina María Jesús , Porcel Carlos , Sáez-Zea Carmen 
Published: September 2023

AbstractIntroductionMild cognitive impairment (CI) has an exponential increase in its prevalence and causes functional deficits and dependence. Its early detection allows for timely treatment and greater therapeutic efficacy. However, mild cognitive impairment (MCI) is currently underdiagnosed. Although recent decades have seen a rise in computerized instruments for the detection and early diagnosis of MCI, showing numerous advantages over the classic paper-and-pencil methods, such as standardized stimulus presentation. However, their limitations include the use of self-administered application without professional supervision. Few of these instruments have Spanish-adapted versions.ObjectiveTo translate, adapt, and validate the computerized Information Processing Assessment Battery (COGNITO) battery in the Spanish population and to develop a portable administration system that facilitates its application in different settings. COGNITO was then administered to 232 Spanish participants (18–89 years) without cognitive impairment, after which preliminary normative data were obtained.ResultsStrong positive correlations were found between the main cognitive domains assessed by COGNITO and the variables of age, educational level, and MEC score. The gender variable only correlated with visuospatial skills, with men outperforming women. The test–retest correlations conducted after 4 weeks with 89 participants revealed adequate reliability coefficients ranging between.63 and.66 (visuospatial skills = 0.35). Internal consistency coefficients were satisfactory in Attention-Executive Functions and Memory domains.ConclusionsThe Spanish adaptation of COGNITO shows adequate psychometric characteristics of validity and reliability. The preliminary normative data provided may contribute to the early detection of cognitive impairments associated with both normal aging and various types of neurological pathology. This tool has great utility and versatility for neuropsychological practice.
VISTA: visualizing the spatial transcriptome of the C.elegans nervous system
Authors: Liska David , Wolfe Zachery , Norris Adam 
Published: September 2023

Abstract

Summary
Profiling the transcriptomes of single cells without sacrificing spatial information is a major goal of the field of spatial transcriptomics, but current technologies require tradeoffs between single-cell resolution and whole-transcriptome coverage. In one animal species, the nematode worm Caenorhabditis elegans, a comprehensive spatial transcriptome with single-cell resolution is attainable using existing datasets, thanks to the worm’s invariant cell lineage and a series of recently generated single cell transcriptomes. Here we present VISTA, which leverages these datasets to provide a visualization of the worm spatial transcriptome, focusing specifically on the nervous system. VISTA allows users to input a query gene and visualize its expression across all neurons in the form of a “spatial heatmap” in which the color of a cell reports the expression level. Underlying gene expression values (in Transcripts Per Million) are displayed when an individual cell is selected. We provide examples of the utility of VISTA for identifying striking new gene expression patterns in specific neurons, and for resolving cellular identities of ambiguous expression patterns generated from in vivo reporter genes. The ability to easily obtain gene-level snapshots of the neuronal spatial transcriptome should facilitate studies on neuron-specific gene expression and regulation and provide a template for the high-resolution spatial transcriptomes the field hopes to obtain for various animal species in the future.

Availability and implementation
VISTA is freely available at the following URL: https://public.tableau.com/app/profile/smu.oit.data.insights/viz/VISTA_16814210566130/VISTA.
wTSA-CRAFT: an open-access web server for rapid analysis of thermal shift assay experiments
Authors: Reys Victor , Kowalewski Julien , Gelin Muriel , Lionne Corinne 
Published: September 2023

Abstract

Motivation
The automated data processing provided by the TSA-CRAFT tool enables now to reach high throughput speed analysis of thermal shift assays. While the software is powerful and freely available, it still requires installation process and command line efforts that could be discouraging.

Results
To simplify the procedure, we decided to make it available and easy to use by implementing it with a graphical interface via a web server, enabling a cross-platform usage from any web browsers. We developed a web server embedded version of the TSA-CRAFT tool, enabling a user-friendly graphical interface for formatting and submission of the input file and visualization of the selected thermal denaturation profiles. We describe a typical case study of buffer condition optimization of the biologically relevant APH(3')-IIb bacterial protein in a 96 deep-well thermal shift analysis screening.

Availability and implementation
wTSA-CRAFT is freely accessible for noncommercial usage at https://bioserv.cbs.cnrs.fr/TSA_CRAFT.
High-definition blood flow imaging improves quantification of left ventricular volumes and ejection fraction
Authors: Gama Francisco , Custódio Pedro , Tsagkridi Aliki , Moon James , Lloyd Guy , Treibel Thomas A , Bhattacharyya Sanjeev 
Published: September 2023

Abstract

Aims
The accuracy and reproducibility of echocardiography to quantify left ventricular ejection fraction (LVEF) is limited due to image quality. High-definition blood flow imaging is a new technique which improves cavity delineation without the need for medication or intravenous access. We sought to examine the impact of high-definition blood flow imaging on accuracy and reproducibility of LV systolic function assessment.

Methods and results
Prospective observational study of consecutive patients undergoing 2D and 3D transthoracic echocardiography (TTE), high-definition blood flow imaging, and cardiac magnetic resonance (CMR) within 1 h of each other. Left ventricular systolic function characterized by left ventricular end-systolic volumes and left ventricular end-diastolic volumes and LVEF were measured. Seventy-six patients were included. Correlation of 2D TTE with CMR was modest (r = 0.68) with a worse correlation in patients with three or more segments not visualized (r = 0.58). High-definition blood flow imaging was feasible in all patients, and the correlation of LVEF with CMR was excellent (r = 0.88). The differences between 2D, high-definition blood flow, and 3D TTE compared to CMR were 5 ± 9%, 2 ± 5%, and 1 ± 3%, respectively. The proportion of patients where the grade of LV function was correctly classified improved from 72.3% using 2D TTE to 92.8% using high-definition blood flow imaging. 3D TTE also had excellent correlation with CMR (r = 0.97) however was only feasible in 72.4% of patients.

Conclusion
High-definition blood flow imaging is highly feasible and significantly improves the diagnostic accuracy and grading of LV function compared to 2D echocardiography.
Theorizing Strategic Narrative Disruption: Local Non-State Actors and India’s COVID-19 Narrative
Authors: Barthwal-Datta Monika 
Published: September 2023

Abstract
At times of global crises, political elites may attempt to (re)position states they represent as having particular roles at the global level. How might their efforts be disrupted? The idea of “disruption”, and how it relates to contestation, remains under-explored in the strategic narratives literature. In this article, I develop a preliminary theorization of strategic narrative “disruption,” through an empirically rich investigation of the counternarrative of the COVID-19-related domestic migrant crisis in India by local critical media actors. This counternarrative, I argue, constituted the migrant crisis in ways that served to disrupt the Indian government’s emergent global-level strategic narrative of India's role in the COVID-19 pandemic. Developing the idea of disruption as distinct from, and providing the discursive raw materials for, narrative contestation, I show how attempts by political actors to narratively (re)position the state around specific, identity-affirming roles in global politics may be disrupted by locally produced counternarratives that complicate or contradict key claims in the former. In new media ecologies where narratives gain resonance quickly and widely, such counternarratives become available to global audiences and give rise to new discursive framings that become available for use in future narrative contestation.
Predictability: a mistreated virtue of competition law
Authors: Broulík Jan 
Published: September 2023

Abstract
Lacking predictability of enforcement hinders the deterrent function of competition law. This article shows that academic analyses of optimal competition rules do not always treat this factor adequately, paying instead excessive attention to the problem of error. Sometimes, predictability is completely ignored as a relevant factor. At other times, it is taken into account but its effects are framed in a way that undermines their significance. This article further discusses three possible reasons why a part of competition law and economics scholarship engages in such mistreatment of predictability. First, it may be a result of writing convenience. Secondly, the role of predictability in selecting the optimal competition rule may simply be misunderstood. Thirdly, the role of predictability may be belittled intentionally in order to advocate rules benefiting the interests of competition practitioners and/or defendants. This article also briefly explores how problematic each reason is and what solutions might be available.
Political ideology and judicial administration: evidence from the COVID-19 pandemic
Authors: Chilton Adam , Cotropia Christopher , Rozema Kyle , Schwartz David 
Published: September 2023

Abstract
We study the effect of political ideology on the administration of the judiciary by investigating how the chief judges of federal district courts set courthouse policies in response to the COVID-19 pandemic. To do so, we use novel data on the geographic boundaries of federal courts and on the contents of pandemic orders. We account for state and local conditions and policies by leveraging district courts in states that have multiple judicial districts and that have courthouses in multiple counties, and we isolate the effect of chief ideology by using simulations that difference out unobserved district-level effects. We find no consistent evidence that the ideology of chief judges influenced courthouse closures and the authorization of a law allowing for remote proceedings, but we find strong evidence that Republican-appointed chief judges were less likely to require masks and more likely to suspend in-person trials (JEL K00, K40, K41).
Continuum, process, and dyad: three readings of the migration–mobility nexus
Authors: Bitschnau Marco , D’Amato Gianni 
Published: September 2023

Abstract
This article analyzes the Migration–Mobility Nexus (MMN) and shows how it can be conceived as a tool to make sense of the relationship between migration and mobility. Being polysemic, the term nexus offers three different ways to conceptualize this relationship: as continuum, process, and dyad. The first highlights the connected space between long-term and short-term and between monodirectional and circular movements. The second focuses on the sequential transition from migration to mobility in both history and scholarship. Finally, the third suggests that boundless mobility and restricted migration are not contradictory but constitutive of each other. Taking a closer look at these readings, we find that all three can be helpful points of departure for conceptual investigations into contemporary human movement.
Introduction to Special Issue: Family Migration in Times of Crisis
Authors: Wray Helena , Charsley Katharine , Kolbaşı-Muyan Gizem , Smith Lothar 
Published: September 2023

Abstract
This introduction to the Special Issue on Family Migration in Times of Crisis explains why the concept of crisis is a useful prism to uncover new insights into family migration. It recognizes the multivalent character of crises and their tendency to merge and accumulate into what has been called ‘polycrisis’. It recognises critical perspectives on the concept of ‘crisis’, that it represents interpretations of events rather than events themselves and that crises are socially constructed and narrated. Crises present new risks and challenges for migrants and their families. The intersection of the temporalities of crisis with those of family migration can exacerbate periods of separation as well as stress and anxiety about how the family can reunify. The papers in this Special Issue, although they focus on diverse crises and use different approaches and methodologies, reveal some common themes. Crises ‘cascade’ and their impact are often greatest on more marginalized populations. They tend to expose and exacerbate existing inequalities, throwing them into sharper relief. Governments often respond to crises by reverting to more conventional norms of family life. The fragility of transnational life and its dependence on government approval are highlighted, as even the relatively privileged may find rights of movement are curtailed, although they may also more easily find solutions. Migrants and their families respond to crises by seeking to mitigate or avoid separation, and new associations, political contestations, and acts of solidarity may emerge, although their durability, given that interests can diverge over time and crises subside, is unclear.
Eryn: a multipurpose sampler for Bayesian inference
Authors: Karnesis Nikolaos , Katz Michael L , Korsakova Natalia , Gair Jonathan R , Stergioulas Nikolaos 
Published: September 2023

ABSTRACTIn recent years, methods for Bayesian inference have been widely used in many different problems in physics where detection and characterization are necessary. Data analysis in gravitational-wave astronomy is a prime example of such a case. Bayesian inference has been very successful because this technique provides a representation of the parameters as a posterior probability distribution, with uncertainties informed by the precision of the experimental measurements. During the last couple of decades, many specific advances have been proposed and employed in order to solve a large variety of different problems. In this work, we present a Markov Chain Monte Carlo (MCMC) algorithm that integrates many of those concepts into a single MCMC package. For this purpose, we have built Eryn, a user-friendly and multipurpose toolbox for Bayesian inference, which can be utilized for solving parameter estimation and model selection problems, ranging from simple inference questions, to those with large-scale model variation requiring trans-dimensional MCMC methods, like the Laser Interferometer Space Antenna Global Fit problem. In this paper, we describe this sampler package and illustrate its capabilities on a variety of use cases.
Gender differences in patient experience in idiopathic inflammatory myopathies: Subanalysis from the COVAD dataset
Authors: Yoshida Akira , Kim Minchul , Kuwana Masataka , Ravichandran Naveen , Makol Ashima , Sen Parikshit , Lilleker James B , Agarwal Vishwesh , Kardes Sinan , Day Jessica , Milchert Marcin , Joshi Mrudula , Gheita Tamer , Salim Babur , Velikova Tsvetelina , Gracia-Ramos Abraham Edgar , Parodis Ioannis , Nikiphorou Elena , Chatterjee Tulika , Tan Ai Lyn , Nune Arvind , Cavagna Lorenzo , Saavedra Miguel A , Shinjo Samuel Katsuyuki , Ziade Nelly , Knitza Johannes , Distler Oliver , Chinoy Hector , Agarwal Vikas , Aggarwal Rohit , Gupta Latika 
Published: September 2023

ABSTRACTObjectivesWe aimed to investigate the gender-based differences in idiopathic inflammatory myopathies (IIMs), with a particular focus on patient-reported outcomes, utilizing the data obtained through the international COVID-19 vaccination in autoimmune disease e-survey.MethodsPatient-reported outcomes including fatigue, pain, and physical function were extracted from the COVID-19 vaccination in autoimmune disease database and compared between genders, adjusting for demographics and IIM subgroups by multivariable analysis. Inclusion body myositis (IBM) was analysed separately because of the substantial differences in outcomes.ResultsA total of 1197 complete responses from patients with IIMs as of 31 August 2021 were analysed. Seventy percent were women. Women were younger (58 [48–68] vs. 69 [58–75] years old, median [interquartile range], P &lt; .001) and were more likely to suffer from autoimmune multimorbidity, defined as three or more autoimmune diseases in an individual patient (11.4% vs. 2.8%, P &lt; .001). In non-IBM IIMs, fatigue visual analogue scale scores were higher in women (5 [3–7] vs. 4 [2–6], median [interquartile range], P = .004), whereas no significant gender-based differences were noted in IBM. Multivariable analysis in non-IBM IIMs revealed that women, residence in high-income countries, overlap myositis, and autoimmune multimorbidity were independently associated with increased fatigue.ConclusionsWomen with IIMs suffer from autoimmune multimorbidity and experience increased fatigue compared to men.
Self-fueling ferroptosis-inducing microreactors based on pH-responsive Lipiodol Pickering emulsions enable transarterial ferro-embolization therapy
Authors: Wang Chunjie , Zhang Lei , Yang Zhijuan , Zhao Dongxu , Deng Zheng , Xu Jialu , Wu Yumin , Hao Yu , Dong Ziliang , Feng Liangzhu , Liu Zhuang 
Published: September 2023

ABSTRACT
Lipiodol chemotherapeutic emulsions remain one of the main choices for the treatment of unresectable hepatocellular carcinoma (HCC) via transarterial chemoembolization (TACE). However, the limited stability of Lipiodol chemotherapeutic emulsions would lead to rapid drug diffusion, which would reduce the therapeutic benefit and cause systemic toxicity of administrated chemotherapeutics. Therefore, the development of enhanced Lipiodol-based formulations is of great significance to enable effective and safe TACE treatment. Herein, a stable water-in-oil Lipiodol Pickering emulsion (LPE) stabilized by pH-dissociable calcium carbonate nanoparticles and hemin is prepared and utilized for efficient encapsulation of lipoxygenase (LOX). The obtained LOX-loaded CaCO3&hemin-stabilized LPE (LHCa-LPE) showing greatly improved emulsion stability could work as a pH-responsive and self-fueling microreactor to convert polyunsaturated fatty acids (PUFAs), a main component of Lipiodol, to cytotoxic lipid radicals through the cascading catalytic reaction driven by LOX and hemin, thus inducing ferroptosis of cancer cells. As a result, such LHCa-LPE upon transcatheter embolization can effectively suppress the progression of orthotopic N1S1 HCC in rats. This study highlights a concise strategy to prepare pH-responsive and stable LPE-based self-fueling microreactors, which could serve as bifunctional embolic and ferroptosis-inducing agents to enable proof-of-concept transarterial ferro-embolization therapy of HCC.
Protestant Miracle in Dreyer’s Ordet
Authors: Le Fanu Mark 
Published: September 2023

Abstract
While also encompassing Carl Theodor Dreyer’s classics, La Passion de Jeanne d’Arc (1928) and Day of Wrath (1943), this chapter analyzes in depth the unconventionally long scene at the end of the director’s Ordet (1955), which depicts the apparent resurrection of a main character who has died in childbirth. Usually attributed to the Catholic faith, miracles like the resurrection in Ordet foreground an oft-neglected strand in Protestantism—namely, the paradoxical Protestant credo quia absurdum (I believe because it is absurd). Like the movies of Ingmar Bergman (1918–2007), the movies of Carl Theodor Dreyer (1889–1968) epitomize the potential of film as a medium of spiritual-poetic exploration, especially of those areas where faith embraces mystery.
Solving Latino Psychosocial and Health Problems
Authors: Organista Kurt C. 
Published: September 2023

Abstract
This book provides a comprehensive review and analysis of psychosocial and health problems over-affecting Latino populations in the United States, and their mitigation through evidence-based, culturally adapted, and community-based interventions, programs, and institutions. A Sociocultural Practice Model for Working with Latino Populations directs attention to salient social and cultural factors that contextualize Latino psychosocial and health problems and their solutions, including multilevel practice. The first half of the book enhances sociocultural awareness and sensitivity by applying a tight set of social science theories and frameworks to the social and cultural experience of Latinos in America: acculturation, social stratification, racial and ethnic identity development, and intersectionality. New to this edition is a chapter on Americans of Dominican and Central American descent, complementing the updated chapter on Mexican, Puerto Rican, and Cuban Americans from the first edition. The book’s second half features updated chapters on the Latino family, Latinx youth, Latino health, and Latino mental, addressing challenges related to acculturative stress and socioeconomic status. Socioculturally competent interventions including family therapy, full service schools, and integrated behavioral health care, are explored, as is the integration of promotores de salud [health workers] into community-based care. A subsequent chapter provides an updated primer on Latino political power, and a new final chapter to this edition provides an overview of Latino resistance, agency, and social movements. Together, the last two chapters enhance understanding of how Latino communities continue lifting their social positionality, health and well-bein, in ways that can be supported and integrated into multilevel practice.
Sociocultural Practice Model for Latino Populations
Authors: Organista Kurt C. 
Published: September 2023

Abstract
This chapter advances a sociocultural practice model for addressing Latino psychosocial and health problems in a contextualized manner that maximizes the probability of effective assessment and intervention. Relevant constructs such as cultural sensitivity, competence, and humility are critiqued including a brief review of the outcome literature on the components of cultural competence and its effectiveness. Practice model dimensions (availability and access; problem assessment in sociocultural context, interventions congruent with assessment, and accountability to clients) are discussed in relation to the Latino social and cultural experience in America, including an ecological-systems framework for illuminating needed multilevel (micro, meso, and macro) practice approaches.
Latino Power Primer
Authors: Organista Kurt C. 
Published: September 2023

Abstract
This chapter provides practitioners with a primer on Latino political power, including how they may play important roles given the centrality of political power in Latino SES and well-being. Emphasized are the three major dimensions of political power with salient examples of their historical and current enhancement: (1) Participation; (2) Representation; and (3) Policy Benefit. California’s Latino Legislative Caucus is profiled as a blueprint for Latino power given its historical rise and how its priority-agenda legislation reflects the state’s historical shift from policy done to Latinos to policy done for Latinos, as well as for working-class California more generally.