bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biomarkers can Predict COVID-19 Disease
Authors: Sharma Utkarsh , Sharma Shikha 
Published: November 2023

Abstract::
Health professionals have been confronted with a series of challenges because of the ongoing
pandemic of coronavirus disease 2019 (COVID-19). To save the greatest number of lives possible,
it is essential to make a prompt diagnosis and admission to the hospital, as well as to stratify
risks, make efficient use of intensive care services, choose appropriate treatments, monitor patients,
and ensure a prompt discharge. Laboratory markers, also known as biomarkers, can provide additional
information that is objective and has the potential to significantly influence various aspects of
patient care. Clinical assessment is necessary, but laboratory markers can provide this information.
The COVID-19 virus is not an infection that causes the respiratory system; rather, it is a multisystem
disease that is caused by a diffuse system-wide process that involves a complex interplay of the immune,
nervous, and endocrine systems in inflammatory and coagulative cascades. A wide variety of
potential biomarkers have been uncovered because of a better understanding of the virus's effects on
the body and how the body responds to them. Here, the pathophysiology and current data are examined
in relation to various kinds of biomarkers, such as immunological and inflammation biomarkers,
coagulation and hematological biomarkers, as well as cardiac, biochemical, and other biomarkers.
This review provides a comprehensive analysis of the research on the association between biomarkers
and clinical characteristics, viral load, treatment efficacy, and how this knowledge might
most usefully contribute to patient care.
The Association of Dietary Inflammatory Index and Cognitive Function in
Iranian Elders
Authors: Mohseni Maryam , Shivappa Nitin , Shojaei Mehrnaz , Bagherniya Mohammad , Mohammadi Hamed , Hasanzadeh Akbar , Hébert James R , Askari Gholamreza , Sahebkar Amirhossein 
Published: November 2023

Background:
Cognitive impairment is amongst the most substantial mental health
problems in elderly people, and inflammation is an underlying mechanism for cognitive impairment.
The dietary inflammatory index (DII®) reflects the overall inflammatory potential of
individuals’ diets. The current study aimed to assess the relationship between the DII and cognitive
function among the Iranian old population.

Methods:
This cross-sectional study was conducted on 221 subjects≥65 years old in healthcare
centers in five socioeconomically distinct districts of Tehran, Iran. Dietary intake data were obtained
using a validated food frequency questionnaire (FFQ). Energy-adjusted-DII (E-DIITM)
scores were calculated for each participant according to a total of 35 food parameters, which
were available from the FFQ. Mini mental state examination (MMSE), a brief screening questionnaire
was used to assess cognitive function.

Results:
E-DII scores were not significantly associated with cognitive function, both in the
crude model (β=-0.04, P-value=0.82) and after adjusting for potential confounders (β=0.22, Pvalue=
0.14). Additionally, in the unadjusted model, individuals in the highest tertile of E-DII
score had increased odds of mild cognitive impairment (OR=1.13, p-trend=0.01) compared to
those older adults in the lowest tertile of E-DII score. However, after controlling for potential
confounders, these relationships faded (AOR=1.46, p-trend=0.12).

Conclusion:
The findings of the present study showed no significant relationship between E- DII and
cognitive function among the Iranian elderly. Future prospective studies should be undertaken to explore
the association between diet-associated inflammation and cognitive decline in the elderly.
THE IMPACT OF LEMONILO GREEN MARKETING ON PURCHASE INTENTION
Authors: Riyanto Ricarhdus Rikky , Sander Ongky Alex , Megawati Yenli , Elim Rickel Arial Kaisar , Cerlysia Cerlysia 
Published: November 2023

Green marketing concept is getting popular in Indonesia and the world. Various food companies start innovating and launching food brands that use environmentally friendly concept. This research aims to identify impact of environmental concern, attitude toward green products purchase and on Lemonilo purchase intention. This research uses quantitative approach method by using primary data sources from e-questionnaire. The research result shows there is a significant impact of environmental concern on attitude toward green products purchase. The research also found that there is a significant impact of attitude toward green products on Lemonilo purchase intention. However, there is no significant impact of environmental concern on Lemonilo Purchase Intention.
THE IMPACT OF INNOVATION, BRAND IMAGE, AND SOCIAL MEDIA MARKETING ON MENANTEA PURCHASE INTENTION
Authors: Frandi Toni , Ongky Alex Sander1  , Soesilo Ferdinandus , Riza Fahrul , Sidarta Eric 
Published: November 2023

The rapid advancement of technologies and information has required companies to be more careful and thorough in the business competition especially in the food and beverage industry. As the industry is getting more competitive, companies should focus more on innovation, brand image and social media marketing to attract more customers buying their products. Few studies have explored the factors that influence consumer’s intention to buy products from small-medium enterprise in Indonesia. Small-medium enterprise should consider the factors such as brand image and social media marketing that may influence consumer’s purchase intention. This study attempts to establish a framework of factors affecting consumer’s intention on buying products of food and beverage from small-medium enterprise in Indonesia called Menantea. Several independent variables in this research are innovation, brand image and social media marketing. And the dependent variable is purchase intention. This research focuses on investigating the impact of innovation, brand image and social media marketing on consumer’s purchase intention on Menantea. This research was conducted on Menantea customers in Indonesia. The sampling method used non-probability sampling with a sampling size of 124 samples. The data was collected by the means of questionnaire. This type of research is quantitative and uses the SPSS 25. The results showed that brand image has a significant positive impact on consumer’s purchase intention on Menantea, social media marketing has a significant positive impact on consumer’s purchase intention on Menantea and innovation has no significant positive impact on consumer’s purchase intention on Menantea.
TRANSFORMATION OF MARKETING ROLE STRATEGY IN REALIZING PURCHASE INTENTION
Authors: Marwan Jubery , Raharjo Paiman , Rachmatsyah T. Herry , Mega Zahera 
Published: November 2023

The transformation of marketing role strategy through social media is very decisive. This technology raises the views and mindset of society radically, whereas the society is very dependent on the technology used. On the other way, producers have their own views on the involvement of social media in influencing people's purchase intention in possible ways. Through the role of public figures or celebrities, promotion through social media can increase consumer purchase intention. This study aims to analyze the transformation of the role of marketing strategy in realizing consumer purchase intention. The sampling method used quantitative methods with a sample of 98 culinary tourism doer. Where the entire population is used as a sample. The results of the analysis show that; there is an influence of marketing strategy on purchase intention through celebrity endorsement variable.
VALIDATING FACTORS AFFECTING PEOPLE’S INTENTION TO USE FINANCE COMPANIES’ SERVICES IN INDONESIA
Authors: Keni Keni , Wilson Nicholas , Alexander Alexander 
Published: November 2023

For the past decades, leasing and consumer finance had become the most popular types of service used and chosen by Indonesians to conduct various kind of purchasing activities toward productive and consumptive assets that people want to buy, such as cars, motorcycles, machineries, and the other kind of productive or consumptive assets. In this case, such behaviour was important to be thoroughly understood and evaluated in order to understand why these people opted to use leasing or consumer finance services as opposed to directly pay for these kinds of assets themselves. Therefore, this research attempt to thoroughly evaluated and validated some factors which were hypothesized could significantly affect people’s intention to use leasing or consumer finance services for the assets that these people were buying. Implementing purposive sampling in order to ensure that all respondents who participated in this study had conformed to all criteria set in this research, questionnaires were distributed to a total of 123 respondents who’ve used leasing or consumer finance services for the assets that they bought (such as cars, motorcycles, and machineries) participated in this research. All of these data then were thoroughly analysed using partial least squares-structural equation modelling (PLS-SEM) using SmartPLS 4 software. Based on the results of the data analyses obtained in this study, three factors, namely attitude toward using leasing/consumer finance services, subjective norm and perceived financial risk toward the product significantly affect people’s intention to buy assets through finance companies who provide leasing and/or consumer finance (financial services) in Indonesia.
Time- and Energy-Saving Potentials of Efficient Urban Air Mobility Airspace Structures
Authors: Preis Lukas , Husemann Michael , Shamiyeh Michael 
Published: November 2023

Novel electric propulsion technology has given rise to thinking about urban air mobility in a new way with its expected high degree of operational flexibility. The designs of electric vertical takeoff and landing configurations are determined by their mission profile, which we found to be oversimplified at many points in the current scientific literature. There is a gap of understanding in how mission profiles impact travel time and energy demand. In this paper, we review various mission designs, formulate a five-segment flight profile (including vertical ascent, climb, cruise, descent, and vertical approach), and apply it on a fleet level of up to 200,000 urban air mobility trips. The demand data originate from the Upper Bavaria region study, OBUAM. In a sensitivity study, we vary the cruise altitude, the height of the vertical flight segments, and the climb and descent angles for two vehicle configurations: a fixed-wing tilt-rotor concept, and a multicopter concept. The main findings for the fixed-wing concept are that the height of the vertical flight segments and the cruise altitude should be as low as possible, and small climb angles (below 7 deg) should be avoided. The multicopter concept, however, is penalized by fast forward flight while being comparatively insensitive to both the cruise altitude and height of the vertical flight segments. Furthermore, we found a tradeoff between time- and energy-optimal flights with the a energy-optimized climb/descent angle at around 10 deg.
Attitudes of the Host Population towards Syrian Refugees: A New Theoretical Perspective
Authors: Şeker Betül Dilara 
Published: November 2023

This study delves into the nuanced attitudes of the host community in Izmir, Turkey, towards Syrian refugees, employing a robust threat and benefit theoretical model. It scrutinizes the multifaceted factors contributing to perceived threats and benefits, elucidates the reasons behind the variation in these attitudes, identifies the individuals responsible for holding these perspectives, pinpoints the specific contexts in which they manifest, examines the temporal dimension of these attitudes, and dissects the profound impact they have on mutual adaptation processes and the formulation of migration policies. A diverse group of 34 participants from the host community actively engaged in semi-structured interviews, comprising 16 females and 18 males across an age spectrum spanning 19 to 64 years. Thematic analysis methodically uncovered that economic and demographic considerations prominently constitute the bedrock of perceived threats, while conversely, the study illuminated financial contributions as pivotal benefits. The in-depth understanding garnered from this study holds significant promise for fostering enduring mutual adaptation between the host and refugee communities, thereby cultivating a more harmonious coexistence. Additionally, this nuanced insight informs the strategic development of immigration policies, ensuring they align with the evolving dynamics of this complex relationship.
Struktur Morfologis dan Makna Kata Majemuk Berunsur Kata Tatsu, Ritsu atau Tateru (立) Dalam Kamus Tagaini Jisho
Authors: 'Alim Muhammad Fattahul , Khasanah Umul 
Published: November 2023

Kata majemuk ialah hasil dari proses penggabungan morfem dasar dengan morfem dasar, baik yang bebas maupun yang terikat, sehingga terbentuk sebuah konstruksi yang memiliki indentitas leksikal yang berbeda maupun baru. Kata majemuk dibagi menjadi 3, yaitu kata majemuk nomina, kata majemuk verba dan kata majemuk adjektiva. Kemudian, diperoleh 18 data kata majemuk nomina dan 7 data kata majemuk verba. Kata majemuk nomina terbentuk berstruktur N + V sebanyak 13 data, dan struktur V + N sebanyak 5 data. Sedangkan kata majemuk verba ditemukan berstruktur V + V sebanyak 5 data, dan struktur N + V sebanyak 2 data. Selain itu, kata majemuk tersebut diklasifikasikan pula berdasarkan makna unsur pembentuknya dan diperoleh hasil, yaitu (1) terbentuk oleh salah satu makna unsur pembentuknya sebanyak 10 data, (2) terbentuk oleh kedua makna unsur pembentuknya sebanyak 9 data, dan (3) tidak terbentuk oleh kedua makna unsur pembentuknya sebanyak 6 data.
KINERJA PEGAWAI DINAS PEMADAM KEBAKARAN DAN PENANGGULANGAN BENCANA KOTA MAKASSAR
Authors: Rahmatullah  
Published: November 2023

Penelitian ini bertujuan untuk mengetahui Kinerja Pegawai Dinas Pemadam Kebakaran dan Penanggulangan Bencana Kota Makassar. Jeni spenelitian yang digunakan dalam penelitian ini adalah jenis penelitian deskriptif kualitatif dengan tipe studi kasus. Teknik pengumpulan data yang dilakukan dalam penelitian ini yaitu dengan melakukan observasi langsung, wawancara. Teknik analisis data yang digunakan adalah Reduksi data, penyajian data, danpenarikan kesimpulan. Keabsahan data digunakan triangulasi yaitu triangulasi waktu, triangulasi sumber, dantriangulasi teknik. Hasil penelitian ini menunjukkan bahawa Kinerja pegawai secara kuantitas ditunjukkan dengan memberikan berbagai pelayanan yang berkaitan dengan input pelaporan, proses penanggulangan, dari segi kualitas menunjukkan pencapaian kinerja yang berkualitas dengan memberikan pelayanan sesuai mutu standardisasi kerja, spesifikasi kerja, dari segi efisiensi menunjukkan kemampuan menjalankan kinerjanya secara efisien sesuai dengan penggunaan waktu kerja yang cepat, tepat, dan teliti, dari efektif ditunjukkan dengan pencapaian kinerja yang efektif melalui kemampuannya untuk selalu hadir, siap sedia, memelihara pekerjaan dan berkesinampungan dalam atas penanganan dan penanggulangan kebakaran/bencana di Kota Makassar.
Analysis of the Ukrainian legislation on labour protection adaptation to the European Union acts
Authors: Petrovska S. A. , Petrovskyi M. V. 
Published: November 2023

The decision of the European Council dated 23 June 2022 to grant Ukraine the status of an EU candidate became a significant incentive for reforms in the country. Reforming labour protection legislation is one of the most urgent tasks for the successful completion of Ukraine’s European integration and for the development of the country’s economy.
The purpose of the article is to study the state of adaptation of Ukrainian legislation in the field of labour protection, in particular, occupational safety and health as well as employees’ health protection, to the legislation of the European Union. To achieve this goal, the general scientific and special scientific methods were used, in particular, dialectical, formal and logical, and comparative legal methods.
The state of implementation of the provisions of the main European directives relating to occupational health and safety in the workplace into Ukrainian legislation is analysed. It has been established that by the beginning of 2023, the provisions of the analysed directives have been implemented only partially, since a significant part of the provisions has not been implemented into Ukrainian labour protection legislation.
On the basis of the study, there have been identified factors that negatively affect the implementation process. Recommendations for improving the efficiency and effectiveness of the implementation of EU acts into Ukrainian legislation have been proposed. The adoption of the necessary regulatory legal acts in the field of labour protection to harmonise Ukrainian legislation with the European one has been substantiated.
The process of Ukrainian legislation adaptation to EU norms requires coordinated cooperation between all branches of government for effective work and successful implementation of their rule-making and law enforcement powers in practice. The main focus of the ongoing process of Ukraine's legislative approximation with the EU should not be on the implementation of individual directives, but on the transfer of the overall architecture of EU legislation on health and safety, starting with the alignment with Framework Directive № 89/391/ЄЕС. In order to create a national state legal system that complies with EU norms, it is necessary to simultaneously adapt existing laws and adopt new legislative acts that comply with the European legal framework.
Voice familiarity in an interactive voice-reminders app for elderly care recipients and their family caregivers
Authors: Valdivia Karen Natalie Penaranda 
Published: November 2023

<p>This thesis focuses on the effect of voice familiarity in voice reminders between elders and their caregivers. An interactive voice application (for desktops and smartphones) was created to study these effects. Past work suggests voice familiarity may contribute to higher understanding from the listener and may help boost physical and audiovisual deficiencies [1, 2]. Therein for this study, seniors and their family care providers along with medical providers were consulted for voice application design and improvement opportunities using two user tests with 17 care dyads and 15 medical care providers. Results from qualitative content analysis found that care dyads prefer familiar voice reminders for routine tasks (like taking medication) and generally find caregiver-voiced reminders to be acceptable, while medical care providers have mixed opinions about older adults using recorded reminders.</p>
Literature Review: Expanded Carrier Screening dan Keputusan Reproduksi
Authors: Haryanti Eliza , Legiran Legiran 
Published: November 2023

Dengan melakukan skrining genetik, calon orang tua dapat memperoleh informasi tentang apakah mereka memiliki peningkatan risiko mengandung anak yang terkena kondisi autosomal resesif atau terkait-X yang nantinya dapat mempengaruhi perencanaan dan tata laksana selama prakonsepsi dan masa kehamilan. Expanded carrier screening (ECS) merupakan pilihan bagi pasien dalam mengambil keputusan reproduksi dengan mempertimbangkan informasi genetik. Artikel ini bertujuan meninjau literatur yang tersedia saat ini tentang faktor-faktor yang terkait dengan pengambilan keputusan pasangan reproduksi setelah mendapat hasil dari ECS. Metode yang digunakan adalah systematic literature review menggunakan alur Preferred Reporting Items for Systematic Reviews (PRISMA) dengan mengumpulkan artikel, sesuai yang didapat dari database PubMed, Wiley Online Library, Science Direct dan Cochrane, dengan kata kunci “reproductive couples”, ”expanded carrier screening ”, “recessive genetic”, “reproductive decisions”. Dari hasil analisis dipilih 8 artikel yang sesuai kriteria. Kesimpulannya adalah pasangan pembawa dengan penyakit parah atau berat cenderung memilih untuk menjalankan tindakan reproduksi. Hasil diskusi dengan pasangan, tingkat kepercayaan, dan kecemasan terhadap pemeriksaan ECS ikut berpengaruh dalam pengambilan keputusan. Konseling pra-test dan pasca-tes sangat penting untuk memberi pemahaman pada pasien secara menyeluruh.
Penerapan Model Concept Sentence Melalui Media Box Magic Untuk Meningkatkan Kemampuan Menulis Sisindiran
Authors: Marwah Sofa Marwah , Sofia Poppy Sofia 
Published: November 2023

Abstrak. Penelitian ini dilatarbelakangi oleh kurangnya kemampuan sisiwa dalam menulis sisindiran. Penelitian ini bertujuan untuk meningkatkan keterampilan menulis sisindiran di kelas XI SMK Setia Bhakti. Metode yang digunakan dalam penelitian ini adalah studi kuasi eksperimen dengan desain penelitian one-group pretest and posttest. Adapun, teknik mengumpulkan data dalam penelitian ini yaitu menggunakan tes unjuk kerja yang terdiri dari kegiatan pretest dan posttest. Adapun yang menjadi sumber data dari penelitian ini adalah siswa kelas XI AKL SMK Setia Bhakti tahun ajaran 2022-2023. Berdasarkan hasil penelitian diketahui rata-rata nilai kemampuan menulis sisindiran siswa sebelum menggunakan model pembelajaran concept sentence dengan media box magic adalah 66,4, sedangkan setelah menggunakan model pembelajaran concept sentence dengan media box magic meningkat menjadi 84,6 dari KKM 75. Ada perbedaan yang signifikan antara kemampuan menulis sisindiran siswa kelas XI AKL SMK Setia Bhakti tahun ajaran 2022-2023 sebelum dan setelah menggunakan model pembelajaran concept sentence dengan media Box magic. Hal itu dapat dilihat dari hasil uji hipotesis, diketahui (11,42) > (2,44), dengan menggunakan tarif kepercayaan 99%. Dapat disimpulkan bahawa model pembelajaran model concept sentence dengan media box magic bisa meningkatkan kemampuan menulis sisindiran siswa kelas XI AKL SMK Setia Bhakti tahun ajaran 2022-2023.
Kata kunci : media box magic; keterampilan menulis; sisindiran
Discovery of potent STAT3 inhibitors using structure-based virtual screening, molecular dynamic simulation, and biological evaluation
Authors: Liu Weifeng , Chu Zhijie , Yang Cheng , Yang Tianbao , Yang Yanhui , Wu Haigang , Sun Junjun 
Published: November 2023

IntroductionSignal transducer and activator of transcription 3 (STAT3) is ubiquitously hyper-activated in numerous cancers, rendering it an appealing target for therapeutic intervention.Methods and resultsIn this study, using structure-based virtual screening complemented by molecular dynamics simulations, we identified ten potential STAT3 inhibitors. The simulations pinpointed compounds 8, 9, and 10 as forming distinct hydrogen bonds with the SH2 domain of STAT3. In vitro cytotoxicity assays highlighted compound 4 as a potent inhibitor of gastric cancer cell proliferation across MGC803, KATO III, and NCI-N87 cell lines. Further cellular assays substantiated the ability of compound 4 to attenuate IL-6-mediated STAT3 phosphorylation at Tyr475. Additionally, oxygen consumption rate assays corroborated compound 4's deleterious effects on mitochondrial function.DiscussionCollectively, our findings position compound 4 as a promising lead candidate warranting further exploration in the development of anti-gastric cancer therapeutics.