bluuebunny/crossref_metadata_2025_split huggingface dataset:
Encircling tendon repair site with collagen sheet in flexor zone 2: retrospective study
Authors: Yaşar Burak 
Published: October 2023

Abstract
Background
Peritendinous adhesion is the most common complication of tendon repairs in the hand and often requires surgical intervention, resulting in increased labor loss and increased treatment costs. Many agents used to reduce tendon adhesion in animal models, however these agents have not entered clinical use. This study is the first-ever clinical study that evaluates encircling tendon repair site with collagen sheet as an anti-adhesion barrier.

Methods
Between December 2014 and January 2020, 156 patients included in this study, with clean cut isolated flexor digitorum profundus (FDP) tendon injury in flexor tendon zone 2. All tendons repaired with modified double Kessler technique. In 76 patients, tendon repair site encircled with collagen sheet. 80 patients were randomly selected from our clinical records and functional results are compared with Strickland’s total active motion grading system.

Results
The mean total range of motion was 79% in the control group and 81% in the collagen sheet group, and there was no statistically significant difference between the two groups (Z: − 1.393, p = 0.164). In the control group, very good and good repair according to Strikland classification was 65/80 (81%). In the collagen sheet group, it was 62/76 (82%), respectively. There was statistically significant difference between 5 FDP TAM measurements between collagen sheet and control group (t(35) = 0.29, p = 0.016, p < 0.05). The mean TAM of the 5 FDP tendons in the collagen sheet group: 83.8 (SD: 8.2) in the and 76.1 (SD: 9.5) in the control group.

Conclusions
For the first time in the literature, functional results of Zone 2 flexor tendon repair using collagen sheets in patients with clean cut tendon injuries reported. However, there were no statistical difference about total active motion between control and collagen sheet group, 5th FDS tendon repairs encircled with collagen sheets had better outcomes. Prospective studies in patient groups with high adhesion risk are recommended.
“There is a fear that you will be attacked just for the act of working in health”: a survey of experiences of violence against healthcare in Colombia
Authors: Crawford☥ Katerina , Florez☥ Tatiana , Rodriguez Mario , Cirado Lendy , Read Róisín , Haar Rohini 
Published: October 2023

Abstract
Background
Colombia has experienced decades of conflict between the government and non-state actors. Attacks on healthcare have been a grave but regular facet of that violence. In response, the Misión Médica (MM) program was developed to support, protect, and defend healthcare. Sporadic violence continues, with many recent attacks perpetrated not by armed actors but by residents. Given the history of conflict and ongoing violence, we sought to capture the perspectives of both healthcare workers (HCWs) and community members (CMs) regarding the characteristics and impacts of attacks on health in Colombia to gain insight into how to better prevent violence and mitigate its impacts.

Methods
A cross-sectional survey was conducted from January to March 2021 in seven departments in Colombia in regions that witnessed attacks on healthcare. Questionnaires were administered to HCWs and CMs via purposive sampling, probing their experiences with attacks on health with both closed and open-ended questions. The categorical responses were stratified by health worker vs. non-health worker and descriptively analyzed. Narrative responses were analyzed via a hybrid deductive/inductive thematic approach.

Results
Seventy-three individuals participated in the study (36 HCWs and 37 cm). Approximately 77% of HCWs believed that attacks on healthcare impacted health outcomes while 68% of CMs did not see a direct connection between violence against healthcare and poor health outcomes. Awareness of the MM program was significantly different between HCWs (83.3%) and CMs (37.8%). The survey responses explored the characteristics of attacks on health, compounded impacts of violence on the health system, personal impacts, and perspectives on mitigation efforts.

Conclusions
The study demonstrates that: (1) attacks on healthcare are context-dependent and require a local lens for mitigation and management; (2) both HCWs and CMs have critical perspectives that must be considered, (3) the impacts of violence against healthcare are complex and compounded and (4) that awareness of the legal protections of the Geneva Conventions must be combined with education on the health impacts for robust protection strategies. Critically, Both CMs and HCWs experience fear and psychosocial ramifications of these attacks, suggesting the need for stronger protections and resources to support the health workforce and the local community.
Piloting a community-based psychosocial group intervention designed to reduce distress among conflict-affected adults in Colombia: a mixed-method study of remote, hybrid, and in-person modalities during the COVID-19 pandemic
Authors: Rattner Michel , James Leah Emily , Botero Juan Fernando , Chiari Hernando , Bastidas Beltrán Guillermo Andrés , Bernal Mateo , Cardona Juan Nicolás , Gantiva Carlos 
Published: October 2023

Abstract
Background
Community members in Quibdó (Choco, Colombia) are highly vulnerable to psychosocial problems associated with the internal armed conflict, poverty, and insufficient public services, and exacerbated by the COVID-19 pandemic. A pilot study was conducted with conflict-affected adults in Quibdó to assess feasibility and outcomes of a community-based psychosocial support group intervention using three different intervention modalities: in-person, remote (conducted online), and hybrid (half of sessions in-person, half-remote). This group model integrated problem-solving and culturally based expressive activities and was facilitated by local community members with supervision by mental health professionals.

Methods
This study utilized a mixed-explanatory sequential design (a quantitative phase deriving in a qualitative phase) with 39 participants and 8 staff members. Participants completed quantitative interviews before and after an eight-week group intervention. A subset of 17 participants also completed in-depth qualitative interviews and a focus group discussion was conducted with staff at post-intervention.

Results
From pre- to post-intervention, participants in all modalities demonstrated improved wellbeing and reduced symptoms of generalized distress, anxiety, depression, and posttraumatic stress. Use of coping skills varied across modalities, with remote groups associated with a decrease in some forms of coping, including use of social support. In qualitative interviews and the focus group discussion, participants and staff described logistical challenges and successes, as well as facilitators of change such as problem resolution, emotional regulation and social support with variations across modalities, such that remote groups provided fewer opportunities for social support and cohesion.

Conclusions
Results offer preliminary evidence that this model can address psychosocial difficulties across the three modalities, while also identifying potential risks and challenges, therefore providing useful guidance for service delivery in conflict-affected settings during the COVID-19 pandemic and other challenging contexts. Implications of this study for subsequent implementation of a Randomized Control Trial (RCT) are discussed.
“You can create a little bit more closure in your own story when someone really connects with it”: exploring how involvement in youth peer support work can promote peer development
Authors: Halsall Tanya , Daley Mardi , Hawke Lisa D. , Henderson Jo , Matheson Kimberly 
Published: October 2023

Abstract
Background
Peer support relates to the provision of social/emotional support that is delivered by individuals with lived experience of a key characteristic that is shared with clients. Although the main objective of peer support is to enhance client outcomes, through their involvement, peers derive a secondary benefit to their own personal development. This study applied a hybrid participatory-realist approach to identify what works, for whom, why and in what circumstances within the LOFT Transitional Age Youth (TAY) peer services. This paper presents findings related to the processes and possible benefits of being involved in peer work for the peer supporters themselves.

Methods
Semi-structured interviews and focus groups were completed with peer and non-peer staff from the TAY program. A qualitative analysis applied a retroductive approach that involved both inductive and deductive processes to identify relevant themes.

Results
Four program theories and one over-arching context were identified through the analyses. Program theories were related to: (1) enhancing self-efficacy and self-determination through peer involvement in program design, (2) increasing peer resiliency and self-care through effective supervision, (3) developing professional skills and opportunities for career advancement through peer practice and (4) overcoming stigma through the recognition of the value of peer lived experience.

Conclusions
Peer practice holds significant potential for the enhancement of the mental health system as well as to increase our understanding of stigma. The findings from this study offer critical new insights into the dynamics of how professional peer practice can support the personal development of youth peers and how programming can be intentionally designed to enhance these benefits.
Engineered live bacteria as disease detection and diagnosis tools
Authors: Tanniche Imen , Behkam Bahareh 
Published: October 2023

AbstractSensitive and minimally invasive medical diagnostics are essential to the early detection of diseases, monitoring their progression and response to treatment. Engineered bacteria as live sensors are being developed as a new class of biosensors for sensitive, robust, noninvasive, and in situ detection of disease onset at low cost. Akin to microrobotic systems, a combination of simple genetic rules, basic logic gates, and complex synthetic bioengineering principles are used to program bacterial vectors as living machines for detecting biomarkers of diseases, some of which cannot be detected with other sensing technologies. Bacterial whole-cell biosensors (BWCBs) can have wide-ranging functions from detection only, to detection and recording, to closed-loop detection-regulated treatment. In this review article, we first summarize the unique benefits of bacteria as living sensors. We then describe the different bacteria-based diagnosis approaches and provide examples of diagnosing various diseases and disorders. We also discuss the use of bacteria as imaging vectors for disease detection and image-guided surgery. We conclude by highlighting current challenges and opportunities for further exploration toward clinical translation of these bacteria-based systems.
MpADC, an l-aspartate-α-decarboxylase, from Myzus persicae, that enables production of β-alanine with high yield by whole-cell enzymatic catalysis
Authors: Liu Pengfu , Xie Saixue , Guo Qian , Chen Yan , Fan Junying , Kumar Nadda Ashok , Huang Xiaoluo , Chu Xiaohe 
Published: October 2023

Abstract
Background
β-Alanine is a precursor of many important pharmaceutical products and food additives, its market demand is continuously increasing nowadays. Whole-cell catalysis relying on the recombinant expression of key β-alanine synthesizing enzymes is an important method to produce β-alanine. Nevertheless, β-alanine synthesizing enzymes found so far have problems including easy inactivation, low expression or poor catalytic activity, and it remains necessary to develop new enzymes.

Results
Herein, we characterized an l-aspartate-α-decarboxylase, MpADC, from an aphid, Myzus persicae. It showed excellent catalytic activity at pH 6.0–7.5 and 37 °C. With the help of chaperone co-expression and N-terminal engineering guided by AlphaFold2 structure prediction, the expression and catalytic ability of MpADC in Escherichia coli were significantly improved. Using 50 g/L of E. coli cells expressing the MpADC-∆39 variant cultured in a 15-L fermenter, 232.36 g/L of β-alanine was synthesized in 13.5 h, with the average β-alanine yield of 17.22 g/L/h, which is best known so far.

Conclusions
Our research should facilitate the production of β-alanine in an environment-friendly manner.
Insights into the diagnosis, vaccines, and control of Taenia solium, a zoonotic, neglected parasite
Authors: Hossain Md. Shahadat , Shabir Shafqat , Toye Philip , Thomas Lian F. , Falcone Franco H. 
Published: October 2023

AbstractTaenia solium taeniasis/cysticercosis (TSTC) is a foodborne, zoonotic neglected tropical disease affecting predominately low- and middle-income countries. Humans are definitive hosts for T. solium, whereas pigs act as intermediate hosts. Taeniasis, i.e. intestinal infection with adult T. solium in the human host, occurs through ingestion of undercooked pork infected with the larval stage (porcine cysticercosis, PCC). Human cysticercosis occurs after humans ingest T. solium eggs, acting as accidental intermediate hosts. Migration of cysticerci to the human brain results in neurocysticercosis (NCC), manifesting in a variety of clinical symptoms, most notably epilepsy. NCC is the leading cause of acquired epilepsy cases in endemic areas. PCC results in reduced pork value because of condemnation or the risk of condemnation of the meat. Available serological diagnostic tests for porcine and human cysticercosis are characterized by low sensitivity and are not cost-effective. An effective vaccine for T. solium cysticercosis in pigs has been developed, although it is not yet commercially available in all endemic countries, and still no vaccine is available for use in humans. This primer highlights the recent development in the field of diagnostic tests and vaccine production and explores possible strategies for future control and eradication of T. solium. In the absence of highly specific diagnostic tests and human vaccines, treatment of infected pigs and tapeworm carriers and prevention of disease transmission remain the principal means to interrupt the zoonotic cycle of T. solium in endemic countries.
Graphical abstract
Chronic bilateral dacryoadenitis caused by SARS-CoV-2 infection: a case report
Authors: Awada Bassem 
Published: October 2023

Abstract
Background
Dacryoadenitis is inflammation of the lacrimal gland, mainly caused by viral infection. It can also be caused by bacterial pathogens and non-infectious processes such as auto-immune diseases and malignancy. Chronic dacryoadenitis is rarely linked to SARS-CoV-2 infection, with only five reports in the literature.

Report
A 26-year-old Arab woman experienced chronic inflammatory dacryoadenitis after a mild SARS-CoV-2 infection, which was successfully treated with oral prednisone.

Conclusions
Dacryoadenitis can occur due to inflammation caused by either SARS-CoV-2 exposure. The treatment typically involves the administration of steroids, with duration to be decided based on clinical response.
A wavelet selection scheme in underwater discharge signal analysis
Authors: Zhang Xiaobing , Lu Binjie , Qiao Liang 
Published: October 2023

AbstractThe analysis of underwater discharge signals is of great significance for its application. Wavelet-based de-noising and analysis technology is an effective means to study underwater discharge signals. The selection of wavelets is the key to the accuracy of wavelet analysis. A scheme of wavelet selection is provided in this paper. Based on the signal characteristics and actual noise, the reference target signal and noisy signal are constructed to ensure the accuracy of wavelet performance evaluation. Cross-correlation coefficient, root mean square error, signal-to-noise ratio, and smoothness are chosen as evaluation indexes and fused by the coefficient of variation method. The selected optimal wavelet is used to process the underwater wire-guided discharge signals. The results show that the scheme is feasible and practical.
Unusual grafts for living-donor liver transplantation
Authors: Yim Seung Hyuk , Min Eun-Ki , Choi Mun Chae , Kim Deok-Gie , Han Dai Hoon , Joo Dong Jin , Choi Jin Sub , Kim Myong Soo , Choi Gi Hong , Lee Jae Geun 
Published: October 2023

Abstract
Purpose
Unusual grafts, including extended left liver plus caudate lobe, right anterior section, and right posterior section grafts, are alternatives to left and right lobe grafts for living-donor liver transplantation. This study aimed to investigate unusual grafts from the perspectives of recipients and donors.

Methods
From 2016 to 2021, 497 patients received living-donor liver transplantation at Severance Hospital. Among them, 10 patients received unusual grafts. Three patients received extended left liver plus caudate lobe grafts, two patients received right anterior section grafts, and five patients received right posterior section grafts. Liver volumetrics and anatomy were analyzed for all recipients and donors. We collected data on laboratory examinations (alanine aminotransferase, total bilirubin, international normalized ratio), imaging studies, graft survival, and complications. A 1:2 ratio propensity-score matching method was used to reduce selection bias and balance variables between the unusual and conventional graft groups.

Results
The median of Model for End-stage Liver Disease score of unusual graft recipients was 13.5 (interquartile range 11.5–19.3) and that of graft–recipient weight ratio was 0.767 (0.7–0.9). ABO incompatibility was observed in four cases. The alanine aminotransferase level, total bilirubin level, and international normalized ratio decreased in both recipients and donors. Unusual and conventional grafts had similar survival rates (p = 0.492). The right and left subgroups did not differ from each counter-conventional subgroup (p = 0.339 and p = 0.695, respectively). The incidence of major complications was not significantly different between unusual and conventional graft recipients (p = 0.513). Wound seromas were reported by unusual graft donors; the complication ratio was similar to that in conventional graft donors (p = 0.169).

Conclusion
Although unusual grafts require a complex indication, they may show feasible surgical outcomes for recipients with an acceptable donor complication.
Vulnerability to seasonal food insecurity as an exposure to risk: the case of the Southern Province of Zambia
Authors: Kitsuki Akinori , Sakurai Takeshi 
Published: October 2023

Abstract
Background
Seasonality is an important aspect of food security for subsistence households in developing countries. Among the multidimensional aspects of food security, this paper focuses on how unexpected negative harvest shocks would affect the seasonal food consumption of households. This is particularly important because, with the increasing threat of climate change, the frequency of extreme weather events such as droughts and floods is expected to increase; this would adversely affect crop yields.

Methods
Given seasonal price changes of staple foods, some households buy them when prices are low and store them for the hunger season (not buy high (NBH) households), while others run out of staple foods before the next harvest and therefore buy them when prices are high (buy high (BH) households). Using three years of weekly household panel data for the Choma and Sinazongwe Districts of the southern province of Zambia, we assess the ability of seasonal consumption smoothing separately for NBH and BH households.

Results
NBH households successfully smooth their consumption over the 12 months of the crop year. In contrast, BH households, especially for households with few assets, reduce total consumption in response to harvest shocks, just after the harvest and during the “hunger season” just before the next harvest. However, in spite of this, the consumption of staple foods is generally insensitive to harvest shocks. Instead, they reduce consumption only of non-staple food items, such as vegetables and meats.

Conclusions
Seasonal food insecurity is exacerbated by negative harvest shocks. We emphasize the significance of policies aimed at increasing public awareness of healthier food choices, empowering households to avoid purchasing maize at high prices, and reducing seasonal price disparities.
The role of objective and subjective knowledge on the attitude and intention of Italian consumers to purchase farmed and wild fish
Authors: Menozzi Davide , Wongprawmas Rungsaran , Sogari Giovanni , Gai Francesco , Parisi Giuliana , Mora Cristina 
Published: October 2023

AbstractIn general, consumers have very little knowledge about production methods employed in the fish sector, and this lack of information contributes to skepticism and confusion when they choose and purchase fish. In our study, we tested the effect of beliefs and objective and subjective knowledge on consumers’ attitude and their intention to purchase farmed and wild fish, both in a control and an informed group. Furthermore, we explored the effect of the intention to purchase farmed or wild fish on fish purchasing frequency. An online survey was conducted in Italy (n = 776) in 2020. The results showed that both objective and subjective knowledge affected the attitudes toward wild and farmed fish; however, only subjective knowledge had an impact on the intention to purchase wild fish. Moreover, the intention to purchase was correlated with fish purchasing frequency, and information about production methods affected consumers' attitudes but did not directly influence their purchasing intentions. This study provides insights that could be considered by policymakers and producer associations/industries to develop and support communication campaigns on fish production methods in terms of safety, healthiness, control, and quality. Thus, our research could help to increase the transparency of information about fish and improve the acceptance and consumption of aquaculture products.
Wedge resection combined with 3D-printed polycaprolactone mesh for caudal septal deviation
Authors: Moon Jee Won , Choi Seok-Youl , Kim Su-Jong , Shin Jae-Min , Park Il-Ho 
Published: October 2023

Background Biocompatibility and stability of three-dimensional printed polycaprolactone mesh grafts for nasal surgery are proven in both animal and human models. However, their safety and durability as batten grafts for caudal septal deviation has not been documented. This study was designed to investigate the efficacy and safety of three-dimensional printed polycaprolactone mesh batten graft in septoplasty using the wedge resection technique for the correction of caudal septal deviation. Methods This retrospective study reviewed the medical records of 20 patients aged ≥ 18 years with caudal septal deviation who underwent septoplasty with wedge resection and three-dimensional printed polycaprolactone mesh graft from a tertiary medical center in South Korea, between December 1, 2019 and May 31, 2021. Those without nasal obstruction before surgery or with a short follow-up period (< 28 days) were excluded from the survey analysis. Results Of the 20 patients (mean age, 48.0 [range, 19–65] years), 17 (85.0%) were male, and three (15.0%) were female. A significant change was noted in the mean nasal obstruction symptom evaluation score (68.2 vs. 15.0, P < .001) in the 17 patients included in the analysis. Postoperative endoscopic evaluation revealed a straight septum in 19/20 (95.0%) patients, and no complications were noted in the postoperative follow-up period of up to 364 days. Conclusions The three-dimensional printed polycaprolactone nasal mesh is safe and provides adequate support to resist the intrinsic memory of the cartilage of the caudal septum. In addition to nasal surgeries, it has great potential as a graft in other reconstructive surgeries. Trial registration Retrospectively registered.