bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intergenerational relations in childhood anxiety: A network approach
Authors: Baartmans Jeanine M. D. , van Steensel Bonny F. J. A. , Kossakowski Jolanda J. , Klein Anke M. , Bögels Susan M. 
Published: November 2023

ObjectiveFamily factors are assumed to play a central role in the development of childhood anxiety disorders. How child and parental anxiety symptoms are intertwined on a symptom and family level has not yet been examined. Such knowledge may lead to a more detailed understanding of the intergenerational relation in anxiety problems. The current study investigated the relation between anxiety in children and their parents at a symptom level using a network approach.MethodParents of 1,452 clinically referred children in the Netherlands completed questionnaires on anxiety about their children and themselves. We examined relations on a symptom level both within persons and between parents and children. In addition, we also compared the relations between parental and child anxiety symptoms in families with children with an anxiety disorder (n = 350) versus families with children who displayed other psychiatric diagnoses (n = 1,102).ResultsAnxiety symptom relations within persons were more intertwined than the symptom relations between family members. Between‐person relations were found among similar anxiety symptoms, suggesting specific intergenerational relations. The feeling of being fearful was found to be a central and connecting symptom in all family members (fathers, mothers, and children). The relations between parental and child anxiety symptoms were more specific (i.e., among similar symptoms) in families with children with an anxiety disorder than in families with children with other types of psychopathologies.ConclusionsThis study found that anxiety symptom associations are present within the family on a detailed (symptom) level. This stresses the importance of future studies to examine factors responsible for this family‐anxiety transmission.
Genomic data reveal new species and the limits of mtDNA barcode diagnostics to contain a global pest species complex (Diptera: Tephritidae: Dacinae)
Authors: Doorenweerd Camiel , San Jose Michael , Geib Scott , Barr Norman , Rubinoff Daniel 
Published: November 2023

AbstractThe Oriental fruit fly Bactrocera dorsalis (Hendel), a global pest that can decimate regional fruit industries and elicit international quarantines, has been the subject of considerable taxonomic confusion. Previous phylogenetic work revealed that B. dorsalis is part of a monophyletic clade containing 12 species. We present restriction site‐associated DNA sequencing (RAD‐seq) genomic data for 2,292 specimens, which unequivocally supports the delimitation of two new species, here described as Bactrocera borneoensis sp. n. Doorenweerd & San Jose and B. incognita sp. n. Doorenweerd & San Jose. We additionally obtained 1,985 Cytochrome C oxidase I (COI) sequences for a subset of the specimens to see which species can be diagnosed with this mtDNA marker and conclude that B. dorsalis, B. incognita, B. carambolae Drew & Hancock, B. raiensis Drew & Hancock, B. occipitalis (Bezzi) and B. kandiensis Drew & Hancock cannot be identified reliably using COI due to introgression—but the newly described species B. borneoensis can be identified using COI. The supposed innocuous species B. raiensis distribution is underestimated in Asia and Africa. Bactrocera kandiensis COI genotypes occur in African flies, but RAD‐seq data confirm that these are B. dorsalis with introgressed B. kandiensis COI. The phylogenomic dataset brings new light to the extent of the B. dorsalis s.l. clade and the morphological and molecular confusion based on COI. This will have ramifications for ecological data—including host and distribution ranges—associated with B. dorsalis s.l. clade species, pest identification protocols and our understanding of the economic importance of the various species in the clade.
On the criteria of the imitation for the artificial intelligent systems in the moral imitation game
Authors: Thomas Jolly 
Published: November 2023

AbstractTo assess the intelligence of machines, Alan Turing proposed a test of imitation known as the imitation game, famously known as the Turing test. To assess whether artificial intelligent (AI) systems could be moral or not, Colin Allen et al. developed a test of imitation in the context of morality, a test known as the Moral Turing Test (MTT), which I will, in this paper, call the moral imitation game. There are arguments against developing any type of MTT or moral imitation game. Rather than developing a moral imitation game, this paper proposes a criterion of imitation for AI systems in the moral scenario. To develop a criterion of imitation, I explore the notion of moral attribution in detail. Within the case of moral attribution, I introduce the subject‐ascriber distinction. The notion of moral attribution and the subject‐ascriber distinction is employed to address the following questions: (a) how is the assessment in MTT arranged?, (b) what is the role of the interrogator in the MTT?, and (c) what information is to be concealed from the interrogator? The first question deals with the aspect of assessment, the second question deals with the reordering of the role of the interrogator and the third one deals with the concealment aspect of the imitation game. After that, a criterion of imitation for AI systems is put forward. Using the subject‐ascriber distinction in moral attribution and David Lewis' Mad Pain and Martian Pain cases, it is argued that the notion of sentience is insignificant for the ascriber for moral attributions.
FvemiR160‐FveARF18A‐FveAP1/FveFUL module regulates flowering time in woodland strawberry
Authors: Luo He , Li Tianyu , Guan Yuhan , Zhang Zhuo , Zhang Zihui , Zhang Zhihong , Li He 
Published: November 2023

SUMMARYFlowering is an indicator of plant transformation from vegetative to reproductive growth. miR160 has been shown to have a significant effect on the growth and development of fruits, leaves, and roots of plants or their stress response to environment, but the participation of miR160 in regulating flowering time in plants is unclear. In this study, we found that two FvemiR160s (FvemiR160a/FvemiR160b) mature sequences in strawberry (Fragaria vesca) were consistent. It was displayed that the miR160 mature sequence is highly conserved in various species, and the miR160 mature sequence formed by the 5′ arm of the MIR160 precursor was more conserved. Three FveARFs in woodland strawberry were negatively regulated by FvemiR160a, among which FveARF18A was the most significant. Phylogenetic analysis indicated that FvemiR160 is closely related to apple (Malus domestica), grape (Vitis vinifera), and Arabidopsis thaliana, while FveARF18A is closely related to RcARF18. Subsequently, we demonstrated that FvemiR160a can target cutting FveARF18A to negatively regulate its expression by RLM‐5′ RACE, cleavage site mutation, and GFP fluorescence assay. Moreover, we observed that FveMIR160a overexpressed plants have advanced flowering, while mFveARF18A overexpressed plants have delayed flowering. We also verified that FveARF18A negatively regulates the expression of FveAP1 and FveFUL by binding their promoters by yeast one‐hybrid, LUC, and GUS assay, and FveAP1 and FveFUL transgenic Arabidopsis showed early flowering phenotype. In addition, the expression level of FvemiR160a was decreased obviously while that of FveARF18A was increased obviously by MeJA, GA and IAA. In conclusion, our study reveals the important role of the FvemiR160‐FveARF18A‐FveAP1/FveFUL module in the flowering process of woodland strawberry and provides a new pathway for studying flowering.
Role of trafficking protein particle complex 2 in medaka development
Authors: Zappa Francesca , Intartaglia Daniela , Guarino Andrea M. , De Cegli Rossella , Wilson Cathal , Salierno Francesco Giuseppe , Polishchuk Elena , Sorrentino Nicolina Cristina , Conte Ivan , De Matteis Maria Antonietta 
Published: November 2023

AbstractThe skeletal dysplasia spondyloepiphyseal dysplasia tarda (SEDT) is caused by mutations in the TRAPPC2 gene, which encodes Sedlin, a component of the trafficking protein particle (TRAPP) complex that we have shown previously to be required for the export of type II collagen (Col2) from the endoplasmic reticulum. No vertebrate model for SEDT has been generated thus far. To address this gap, we generated a Sedlin knockout animal by mutating the orthologous TRAPPC2 gene (olSedl) of Oryzias latipes (medaka) fish. OlSedl deficiency leads to embryonic defects, short size, diminished skeletal ossification and altered Col2 production and secretion, resembling human defects observed in SEDT patients. Moreover, SEDT knock‐out animals display photoreceptor degeneration and gut morphogenesis defects, suggesting a key role for Sedlin in the development of these organs. Thus, by studying Sedlin function in vivo, we provide evidence for a mechanistic link between TRAPPC2‐mediated membrane trafficking, Col2 export, and developmental disorders.
In vitro evaluation of hyperosmotic canine plasma suitable for infusion
Authors: Edwards Thomas H. , Meledeo Michael A. , Peltier Grantham C. , Henderson Alice F. , Pompa Luis A. , Bynum James A. 
Published: November 2023

AbstractObjectiveTo determine the characteristics of canine freeze‐dried plasma (cFDP) as it is serially diluted with sterile water.DesignIn vitro experimental study.SettingGovernment blood and coagulation research laboratory.AnimalscFDP from a commercial manufacturer.InterventionsTen units of cFDP were reconstituted to 100%, 90%, 80%, 70%, 60%, 50%, and 40% of the recommended volume with sterile water. The resultant solutions were analyzed for coagulation factor activity (factors II, V, VII, VIII, IX, X, and XII as well as antithrombin), fibrinogen concentration, prothrombin time, activated partial thromboplastin time, viscosity, osmolality, and kaolin‐activated thromboelastography.Measurements and Main ResultsViscosity, osmolality, and turbidity properties of plasma were increased in a reconstitution volume‐dependent manner, with the 40% suggested volume generating approximately 2‐fold increases in each. Similarly, factor activity levels and fibrinogen concentration increased by approximately 2‐fold over this range in a concentration‐dependent manner. Prothrombin time declined from 11.4 seconds at 100% volume to 10.9 seconds at 70% before increasing to 11.9 seconds at 40%. Activated partial thromboplastin time increased exponentially from 21.8 seconds at 100% rehydration to 100.0 seconds at 40%. R‐time on TEG increased from 3.1 to 13.9 minutes at 50% rehydration, while alpha angle declined from 61.3° to 24.7° over the same range, and the maximum amplitude initially increased from 13.2 mm at 100% water to 18.6 mm at 70% water before dropping back down to 14.6 mm at 50% water. No clotting was observed with 40% rehydration.ConclusionsThe creation of hyperosmotic plasma from cFDP appears feasible with preservation of concentrated coagulation factors, although there are some unexplained effects that happen to coagulation functions at the highest concentrations tested using only 40%–50% of recommended rehydration volume. Further studies are needed to evaluate the hyperosmotic product in vivo.
Energy Recovery Turbine in Cross Country Pipeline
Authors: Ibrahim Shiyas 
Published: November 2023

Abstract
The transportation of fluid in cross country pipelines involves the conversion of mechanical energy into pressure energy through the use of pumps at the mainline pump station. While designing the pipeline system, the pressure energy at originating and intermediate pump stations are designed taking into account the system losses to ensure the required flow right up to the end receipt station at the design pressure.
The incoming pressure at intermediate tap-off receipt stations are higher than the required pressure, which is reduced within acceptable limits through the use of a Control Valve. The control valve used in pipeline systems consists of valves with actuators for throttling of the position based on the required set pressures. There is considerable loss of energy in the pressure control valves since pressure energy is dissipated as heat, noise and vibration. Installation of energy recovery units across the pressure control valve can be a solution to recover energy losses at the pipeline receipt stations. The energy is recovered by utilizing the excess pressure to run an Energy Recovery Turbine (ERT) which in turn runs a generator that produces electricity. This paper will discuss the applications of an ERT in cross country pipeline systems, including the benefits, working principle, and different types of ERT.
Evaluation of Pipeline Venting in Long Pipelines
Authors: Ghosh Pradeep Kumar , Agarwal Deepak , Amid Mohammad 
Published: November 2023

Abstract
Pipelines undergo elevated air pressures during construction and maintenance. The higher pneumatic pressures are used in caliper pigging and cleaning pigging. Pneumatic pressures are also required in special conditions during pipeline maintenance. Higher pneumatic pressures are usually released into the atmosphere through a small vent. Higher pneumatic pressure generally poses elevated risk related to safety. In the past, industry has experienced incidences where objects such as pigs are propelled due to air pressure resulting in untoward incidences.
The paper presents a theoretical approach to estimate the time required to vent the pipeline through an orifice. It is a known fact that the gas escaping through a vent has two different velocity regimes. At high differential pressure, the gas is escaped through a velocity which is known as choked or sonic velocity. The velocity usually depends upon the pressure and density of the air inside the container. At lower differential pressures, the gas escapes through a velocity known as non-choked velocity or sub-sonic velocity.
The gas escape velocity determines the rate of pressure variation inside the vessel. Similarly, the density which depends on pressure also changes. The switchover between gas velocity regimes also makes the problem significantly complex. The paper presents a detailed approach to ascertain the time of venting by solving the underlying equations. Considering the complexity of the problem, the equations are solved using numerical integration using Runge-Kutta method. The complete algorithm for solving the problem is provided in the paper. Additionally, a few cases are discussed in detail for venting of large pipelines.
Using Machine Learning As Part of External Corrosion Direct Assessment to Overcome Data Limitations
Authors: Barton Lewis , Carrell Steve , Ruiz Martinez Oscar , Palmer-Jones Roland 
Published: November 2023

Abstract
Operators need to keep their pipelines fit for purpose, maximise life and control costs. To achieve these aims, effective Integrity Management is essential, with a clear understanding of the relevant threats to the pipeline asset.
External corrosion is one of the main threats faced by operators, costing millions annually in identification, mitigation, and repair. ILI is widely used to identify and size external corrosion. Where in-line inspection (ILI) is not possible, knowledge-based models reliant on data and assumptions for multiple variables are used. Combining the variables that are believed to contribute to corrosion with above ground surveys, are used to identify corrosion “hotspots” for in-field investigation. The process is known as External Corrosion Direct Assessment (ECDA). However, ECDA can present significant uncertainties, often requiring multiple iterations of costly excavations to obtain reasonable confidence in pipeline condition — a major limiting factor to the ECDA approach.
To improve data resolution, Virtual-ILI (V-ILI) has been used to incorporate data collected over many years by ROSEN ILI. The Virtual-ILI, when combined with other relevant data such as rainfall, soil type and coating, contains information of corrosion trends across thousands of pipeline segments. Through machine learning algorithms, trained on this historical data, the incorporation of V-ILI has the potential to substantially reduce uncertainty.
An Innovative Solution for Debris Mapping and Health Assessment of Oil and Gas Pipelines
Authors: Jha Pranab Narayan 
Published: November 2023

Abstract
India has a vast network of pipelines carrying crude oil, petroleum products and natural gas. To accelerate the pace of transformation in the energy sector, there is a need to indigenously develop and deploy sustainable technologies for oil and gas pipelines. The industry spends a significant amount of effort and money in dealing with unwanted debris and wax deposits in pipelines. Early detection of such deposits or blockages is important and useful for optimizing maintenance activities and for remedial actions to avoid catastrophic failures.
Bharat Flow Analytics is a startup that is developing innovative Industry 4.0 products and services that promote safe and reliable operations, energy efficiency, and reducing operating costs of transporting hydrocarbons through pipelines. iPTran, the solution for determining internal diameter changes in a pipeline due to debris and wax deposition resulting in partial or complete blockages, has been indigenously developed and currently undergoing field trials with pipeline operators.
iPTran uses a combination of pipeline hydraulics models, Artificial Intelligence (AI) and Industrial Internet of Things (IIoT) sensors for data collection, analysis, and prognosis. It gives an advantage in accuracy and effort over traditional models and data acquisition systems. iPTran is a non-intrusive technology that can analyse hundreds of kilometres of pipeline sections quickly and provide near real-time status to the operator. A trial of iPTran was conducted on Indian Oil’s 148 km 28-inch diameter section (Viramgam to Koyali) with promising results.
This technology helps to determine the efficiency of transportation which directly impacts pumping costs. It also helps to reduce the risk of stuck pigs during inline inspection and can be utilized to improve the efficiency of the pigging program.
Maximizing the Value of Hydrogen Transportation Chain: A Practical Guide to Hydrogen Repurposing
Authors: Naib Sameera , Sandana Daniel , Gallon Neil , Ruiz Martinez Oscar , Singh Gaurav 
Published: November 2023

Abstract
The deployment of a hydrogen economy at an industrial scale requires pipeline transportation. Duty holders are willing to develop such pipeline infrastructure by taking advantage of the existing hydrocarbon assets. It is unreasonable to expect that pipelines designed for hydrocarbon service can be converted directly to hydrogen without due diligence and in consideration of the distinctive integrity challenges introduced by the transportation of gaseous hydrogen.
The incumbent industry codes do not offer a practical approach to holders of license to operate existing pipeline assets for repurposing it safely and economically for hydrogen transportation. The enforcement of dubious and undue conservatism could penalize the realization and the value of a hydrogen chain economy. This paper provides a guide for operators to repurpose pipelines safely from an integrity-led and holistic perspective. An emphasis is given to the safety and maximum utilization.
This guide is summarized by a ‘Pipeline Hydrogen Repurposing Roadmap’, which has been built from the research and practical experience of the authors in addressing the challenges of existing pipeline for hydrogen conversion.
Anaerobiosis, a neglected factor in phage-bacteria interactions
Authors: Hernández Villamizar Santiago , Chica Cárdenas Luis A. , Morales Mancera Laura T. , Vives Florez Martha J. 
Published: November 2023

ABSTRACT

Phage therapy is a promising alternative in treating bacterial infections; however, understanding how bacteria and phages interact according to the environment is crucial. Although most phage therapy applications are intended for anaerobic environments (such as intestine or wounds), research on the effects of oxygen absence on the phage infection process is scarce . Here, we studied the effect of anoxic conditions in a
Salmonella
sp. – phage model, given the prevalence of this bacterial pathogen in anaerobic environments, and the potential of phage therapy for its control. Our results show that oxygen-deprived conditions affect the life cycle length of the phage and its capacity to control the bacterial population. Changes in host cell size associated with the FtsZ protein were observed, along with a modified emergence of resistance against the phage under different oxygen conditions. Interestingly, transcriptomic analyses revealed that phage infection in aerobic conditions triggers the expression of genes associated with nitrate reduction, an alternative pathway for anaerobic respiration. Meanwhile, uninfected anaerobic cultures displayed the upregulation of genes involved in a different anaerobic metabolic route comprising the transport of thiosulfate and sulfate. Altogether, our results provide insights into the importance of considering oxygen availability as an important factor for phage therapy when working with facultative anaerobic bacteria.

IMPORTANCE
Many parameters affect phage-bacteria interaction. Some of these parameters depend on the environment in which the bacteria are present. Anaerobiosis effect on phage infection in facultative anaerobic bacteria has not yet been studied. The absence of oxygen triggers metabolic changes in facultative bacteria and this affects phage infection and viral life cycle. Understanding how an anaerobic environment can alter the behavior of phages during infection is relevant for the phage therapy success.
Salactin, a dynamically unstable actin homolog in Haloarchaea
Authors: Zheng Jenny , Mallon John , Lammers Alex , Rados Theopi , Litschel Thomas , Moody Edmund R. R. , Ramirez-Diaz Diego A. , Schmid Amy , Williams Tom A. , Bisson-Filho Alexandre W. , Garner Ethan 
Published: November 2023

ABSTRACT

Across the domains of life, actin homologs are integral components of many essential processes, such as DNA segregation, cell division, and cell shape determination. Archaeal genomes, like those of bacteria and eukaryotes, also encode actin homologs, but much less is known about these proteins’
in vivo
dynamics and cellular functions. We identified and characterized the function and dynamics of Salactin, an actin homolog in the hypersaline archaeon
Halobacterium salinarum
. Live-cell time-lapse imaging revealed that Salactin forms dynamically unstable filaments that grow and shrink out of the cell poles. Like other dynamically unstable polymers, Salactin monomers are added at the growing filament end, and its ATP-bound critical concentration is substantially lower than the ADP-bound form. When
H. salinarum’s
chromosomal copy number becomes limiting under low-phosphate growth conditions, cells lacking Salactin show perturbed DNA distributions. Taken together, we propose that Salactin is part of a previously unknown chromosomal segregation apparatus required during low-ploidy conditions.

IMPORTANCE
Protein filaments play important roles in many biological processes. We discovered an actin homolog in halophilic archaea, which we call Salactin. Just like the filaments that segregate DNA in eukaryotes, Salactin grows out of the cell poles towards the middle, and then quickly depolymerizes, a behavior known as dynamic instability. Furthermore, we see that Salactin affects the distribution of DNA in daughter cells when cells are grown in low-phosphate media, suggesting Salactin filaments might be involved in segregating DNA when the cell has only a few copies of the chromosome.