bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Development and Implementation of a School‐Based Dental Sealant Program for Hawaii Public Schools*
Authors: Mattheus Deborah , Loos Joanne R. , Vogeler Azeema 
Published: October 2023

ABSTRACTBACKGROUNDSchool‐based dental sealant programs are noted to increase sealant uptake among children, especially those from low‐income families and those living in rural and underserved areas. However, nationally school‐based dental sealant programs are substantially underutilized. This paper describes a partnership approach to a school‐based dental sealant program for Title 1 public schools in Hawaii.METHODSThe Hawaii Keiki: Healthy and Ready to Learn program partnered with the Hawaii Dental Service to develop and implement an interprofessional, school‐based sealant program (SBSP). This article describes the development of key factors, such as partnerships, an interprofessional team, team roles, policies, and marketing tools to optimize program success.RESULTSThe SBSP has completed over 3 academic years of implementation in Hawaii public schools. In its initial year (school year [SY] 2019‐2020), which presented challenges due to the COVID‐19 pandemic, it served 6 schools (106 students screened) on 1 island. It expanded to 14 schools on 1 island (193 students screened) in its second year (SY 2020‐2021), 28 schools on 3 islands (653 students screened) in its third year (SY 2021‐2022), and during the Fall of the fourth year, the program reached 50 schools on 3 islands (1821 students screened) and is projected to reach over 70 schools by the end of SY 2022‐2023.CONCLUSIONTaking advantage of strategic partnerships and key interprofessional team members, a school‐based dental sealant program can help to improve the oral health of children in public schools by helping to decrease barriers to care.
FDI spillovers, new industry development, and economic growth
Authors: Nguyen‐Huu Thanh Tam , Pham Ngoc‐Sang 
Published: October 2023

AbstractThe paper investigates the optimal strategy of a small open economy receiving foreign direct investment (FDI) in an optimal growth context. We prove that no domestic firm can enter the new industry when the multinational enterprise's productivity or the fixed entry cost is high. Nevertheless, the host country's investment stock converges to a higher steady state than an economy without FDI. A domestic firm enters the new industry if its productivity is high enough. Moreover, the domestic firm can dominate or even eliminate its foreign counterpart.
Wintersweet (Chimonanthus praecox) toxicity in 5 sheep
Authors: Knapp Cambrey , Van Dyke Thomas , Foster Derek 
Published: October 2023

AbstractTwo sheep presented with acute tonic‐clonic seizures, opisthotonos, absent pupillary light reflexes and abnormal vital signs within 18 hours after observed consumption of leaves from an ornamental shrub later identified as wintersweet (Chimonanthus praecox). Despite symptomatic treatment, both sheep died. Three other sheep that consumed the plant died after displaying similar clinical signs, resulting in 2 deaths the prior evening and 1 recovery the next morning. Gross necropsy and histologic findings were diagnostically inconclusive. Rumen contents tested positive for the alkaloid calycanthine, a centrally‐acting convulsant known to be present in wintersweet. Case reports of calycanthine toxicity in ruminants are limited, with no detailed reports published in the United States. Calycanthine has been isolated from the seeds, flowers, and leaves of the plant. Wintersweet is part of the family Calycanthaceae that including 3 species native to North America, all of which pose a neurologic risk to ruminants if consumed.
Mitochondrial genome sequence comparisons indicate that the elephant louse Haematomyzus elephantis (Piaget, 1869) contains cryptic species
Authors: Kelly Sarah , Dong Yalun , Wang Wei , Matthee Sonja , Wentzel Jeanette M. , Durden Lance A. , Shao Renfu 
Published: October 2023

AbstractThe parvorder Rhynchopthirina contains three currently recognised species of lice that parasitize elephants (both African savanna elephant Loxodonta africana and Asian elephant Elephas maximus), desert warthogs (Phacochoerus aethiopicus) and Red River hogs (Potamochoerus porcus), respectively. The Asian elephant lice and the African savanna elephant lice are currently treated as the same species, Haematomyzus elephantis (Piaget, 1869), based on morphology despite the fact that their hosts diverged 8.4 million years ago. In the current study, we sequenced 23 mitochondrial (mt) genes of African savanna elephant lice collected in South Africa and analysed the sequence divergence between African savanna elephant lice and previously sequenced Asian elephant lice. Sequence comparisons revealed >23% divergence for the 23 mt genes as a whole and ~17% divergence for cox1 gene between African savanna and Asian elephant lice, which were far higher than the divergence expected within a species. Furthermore, the mt gene sequence divergences between these lice are 3.76–4.6 times higher than that between their hosts, the African savanna and Asian elephants, which are expected for the co‐divergence and co‐evolution between lice and their elephant hosts. We conclude that (1) H. elephantis (Piaget, 1869) contains cryptic species and (2) African savanna and Asian elephant lice are different species genetically that may have co‐diverged and co‐evolved with their hosts.
Higher obesity class is associated with more severe esophageal symptoms and reflux burden but not altered motor function or contractile reserve
Authors: Hiramoto Brent , Redd Walker D. , Muftah Mayssan , Jonnadula Saikiran , Okwara Noreen C. , Jenkins Andrew , Cricco‐Lizza Eliza , Lee Darren J. H. , Cai Jennifer X. , Chan Walter W. 
Published: October 2023

AbstractBackgroundPatients with obesity often report esophageal symptoms, with abnormal reflux and esophageal motility suggested as potential mechanisms. However, prior studies showed varying results, often limited by study design/size and esophageal function/symptom measures utilized. We aimed to examine the relationship between obesity and objective esophageal function testing and patient‐reported outcomes, utilizing prospective symptom, manometric and reflux monitoring data with impedance.MethodsAdults referred for high‐resolution impedance‐manometry (HRiM) and multichannel intraluminal impedance‐pH monitoring (MII‐pH) to evaluate esophageal symptoms were enrolled. Validated symptom and health‐related quality of life (HR‐QOL) instruments were prospectively collected: GERDQ, reflux symptoms index (RSI), dominant symptom intensity (DSI, multiplied 5‐point Likert scales for symptom frequency/severity), global symptom severity (GSS, 100‐point visual analog scale), and Short Form‐12 (SF‐12) for HR‐QOL. Esophageal function testing measures were compared across body mass index (BMI) categories and correlated with patient‐reported outcomes.Key ResultsSeven hundred and fifty four patients were included (Normal:281/Overweight:253/Class I obesity:137/Class II/III obesity:83). Reflux burden measures on MII‐pH (acid exposure time, total reflux episodes, bolus exposure time), conclusive pathologic reflux (Lyon), and hiatal hernia were increased in higher obesity classes compared to normal BMI. Class II/III obesity was associated with more normal/hypercontractile swallows, less ineffective swallows, and better bolus transit on HRiM. BMI correlated positively with GERDQ/RSI/DSI/GSS, and negatively with physical component score (SF‐12). Esophageal symptom severity and HR‐QOL correlated strongly with MII‐pH findings, but not HRiM measures.Conclusions/InferencesObesity is associated with increased esophageal symptom burden and worse physical HR‐QOL, which correlate with higher acid/bolus reflux burden but not altered esophageal motility/transit/contractile reserve.
Time‐resolved systems analysis of the induction of high photosynthetic capacity in Arabidopsis during acclimation to high light
Authors: Baker Christopher R. , Cocuron Jean Christophe , Alonso Ana Paula , Niyogi Krishna K. 
Published: October 2023

Summary
Induction of high photosynthetic capacity is a key acclimation response to high light (HL) for many herbaceous dicot plants; however, the signaling pathways that control this response remain largely unknown. Here, a systems biology approach was utilized to characterize the induction of high photosynthetic capacity in strongly and weakly acclimating Arabidopsis thaliana accessions.
Plants were grown for 5 wk in a low light (LL) regime, and time‐resolved photosynthetic physiological, metabolomic, and transcriptomic responses were measured during subsequent exposure to HL.
The induction of high nitrogen (N) assimilation rates early in the HL shift was strongly predictive of the induction of photosynthetic capacity later in the HL shift. Accelerated N assimilation rates depended on the mobilization of existing organic acid (OA) reserves and increased de novo OA synthesis during the induction of high photosynthetic capacity. Enhanced sucrose biosynthesis capacity increased in tandem with the induction of high photosynthetic capacity, and increased starch biosynthetic capacity was balanced by increased starch catabolism.
This systems analysis supports a model in which the efficient induction of N assimilation early in the HL shift begins the cascade of events necessary for the induction of high photosynthetic capacity acclimation in HL.
Stages of aestivation as a physiological state and the related biochemical composition in the grain chinch bug (Macchiademus diplopterus)
Authors: Smit R. , Neven L. G. , Johnson S. A. 
Published: October 2023

AbstractThe grain chinch bug (Macchiademus diplopterus Distant) is a phytosanitary pest, endemic to the Western Cape in South Africa. At the start of the aestivation phase of their lifecycle, grain chinch bugs seek sheltering sites, which potentially include fruit and fruit trees if orchards are near host plants. Aestivating grain chinch bug on export fruit is considered contaminant or hitchhiker phytosanitary pests. Previous studies have indicated that the grain chinch bug has the ability to become more tolerant of thermal stresses as they progress through their aestivation cycle. To examine the potential physiological changes that occur during aestivation, molecular (soluble protein identification) and biochemical (macromolecule) analyses were performed on the insects before entering aestivation, as well as early, mid, mid‐late and late aestivation periods. Analyses provided useful information on the abundance and identity of individual soluble proteins and concentration of macromolecules, indicating whether compounds are up‐ or down‐regulated throughout the aestivation cycle. The focus of this investigation was to examine the influence of heat shock proteins and proteins involved in energy production and metabolism throughout the aestivation period. Results provide insight into the thermo‐tolerance capabilities or mechanisms of the grain chinch bug. The significant decrease in the number of individual proteins identified in samples before aestivation compared to early aestivation indicated the insects' progression into a hypometabolic state. During the early, mid and mid‐late aestivation periods (from December to May), large volumes of fruit are exported from South Africa. An increase in abundance of proteins, such as smHsp20, Hsp10, 70, 80 and 90, occurred during the mid/mid‐late aestivation period compared with the early period. This indicated the potential role of heat shock proteins in the insect's ability to increase its thermo‐tolerance at a later stage within the aestivation cycle.
How to judge intentionally
Authors: Peacocke Antonia 
Published: October 2023

AbstractContrary to popular philosophical belief, judgment can indeed be an intentional action. That's because an intentional judgment, even one with content p, need not be intentional as a judgment that p. It can instead be intentional just as a judgment wh‐ for some specific wh‐ question—e.g. a judgment of which x is F or a judgment whether p. This paper explains how this is possible by laying out a means by which you can perform such an intentional action. This model of intentional judgment does not stand in tension with the fact that judgment is causally regulated for truth, and that it is correct only if it is true. On the contrary, the structure of intentional action explains how an intentional judgment has these features. An extended example is developed, and sufficient conditions on intentional judgment are laid out.
Overexpression of the Small Ubiquitin‐Like Modifier protease OTS1 gene enhances drought tolerance in sugarcane (Saccharum spp. hybrid)
Authors: Masoabi M. , Burger N. F. V. , Botha A.‐M. , Le Roux M. L. , Vlok M. , Snyman S. , Van der Vyver C. 
Published: October 2023

ABSTRACT
Sugarcane is an economically important crop plant across the globe as it is the primary source of sugar and biofuel. Its growth and development are greatly influenced by water availability; therefore, in periods of water scarcity, yields are severely compromised. Small Ubiquitin‐Like Modifier (SUMO) proteases play an important role in stress responses by regulating the SUMO‐related post‐translational modification of proteins.
In an attempt to enhance drought tolerance in sugarcane, this crop was genetically transformed with a cysteine protease (OVERLY TOLERANT TO SALT‐1; OTS1) from Arabidopsis thaliana using particle bombardment. Transgenic plants were analysed in terms of photosynthetic capacity, oxidative damage, antioxidant accumulation and the SUMO‐enrich protein profile was assessed.
Sugarcane transformed with the AtOTS1 gene displayed enhanced drought tolerance and delayed leaf senescence under water deficit compared to the untransformed wild type (WT). The AtOTS1 transgenic plants maintained a high relative moisture content and higher photosynthesis rate when compared to the WT. In addition, when the transgene was expressed at high levels, the transformed plants were able to maintain higher stomatal conductance and chlorophyl content under moderate stress compared to the WT. Under severe water deficit stress, the transgenic plants accumulated less malondialdehyde and maintained membrane integrity. SUMOylation of total protein and protease activity was lower in the AtOTS1 transformed plants compared to the WT, with several SUMO‐enriched proteins exclusively expressed in the transgenics when exposed to water deficit stress.
SUMOylation of proteins likely influenced various mechanisms contributing to enhanced drought tolerance in sugarcane.
Photosynthesis, leaf hydraulic conductance and embolism dynamics in the resurrection plant Barbacenia purpurea
Authors: Nadal Miquel , Carriquí Marc , Badel Eric , Cochard Hervé , Delzon Sylvain , King Andrew , Lamarque Laurent J. , Flexas Jaume , Torres‐Ruiz José M. 
Published: October 2023

AbstractThe main parameters determining photosynthesis are stomatal and mesophyll conductance and electron transport rate, and for hydraulic dynamics they are leaf hydraulic conductance and the spread of embolism. These parameters have scarcely been studied in desiccation‐tolerant (resurrection) plants exposed to drought. Here, we characterized photosynthesis and hydraulics during desiccation and rehydration in a poikilochlorophyllous resurrection plant, Barbacenia purpurea (Velloziaceae). Gas exchange, chlorophyll fluorescence, and leaf water status were monitored along the whole dehydration‐rehydration cycle. Simultaneously, embolism formation and hydraulic functioning recovery were measured at leaf level using micro‐computed tomography imaging. Photosynthesis and leaf hydraulic conductance ceased at relatively high water potential (−1.28 and −1.54 MPa, respectively), whereas the onset of leaf embolism occurred after stomatal closure and photosynthesis cessation (<−1.61 MPa). This sequence of physiological processes during water stress may be associated with the need to delay dehydration, to prepare the molecular changes required in the desiccated state. Complete rehydration occurred rapidly in the mesophyll, whereas partial xylem refilling, and subsequent recovery of photosynthesis, occurred at later stages after rewatering. These results highlight the importance of stomata as safety valves to protect the vascular system from embolism, even in a plant able to fully recover after complete embolism.
Combined analysis of microRNA and mRNA profiles provides insights into the pathogenic resistant mechanisms of the lotus rhizome rot
Authors: Zhao Shuping , Tan Mengying , Zhu Yamei , Zhang Yao , Zhang Chuyan , Jiao Jiao , Wu Peng , Feng Kai , Li Liangjun 
Published: October 2023

AbstractLotus rhizome rot caused by Fusarium oxysporum is a common vascular fungal disease in plants that significantly impacts the yield. However, only a few studies have studied the mechanism of Nelumbo nucifera responding to lotus rhizome rot. Here, we investigated the pathogenic genes and miRNAs in lotus rhizome rot to uncover the pathogenic resistant mechanisms by transcriptome and small RNA sequencing of lotus roots after inoculation with Fusarium oxysporum. GO and KEGG functional enrichment analysis showed that differential miRNAs were mostly enriched in starch and sucrose metabolism, biosynthesis of secondary metabolites, glutathione metabolism, brassinosteroid biosynthesis and flavonoid biosynthesis pathways. Twenty‐seven upregulated miRNAs, 19 downregulated miRNAs and their target genes were identified. Correlation analysis found that miRNAs negatively regulate target genes, which were also enriched in starch and sucrose metabolism and glutathione metabolism pathways. Their expression was measured by reverse transcription quantitative PCR (qRT‐PCR), and the results were consistent with the transcriptome analysis, thus verifying the reliability of transcriptome data. We selected three miRNAs (miRNA858‐y, miRNA171‐z and a novel miRNA novel‐m0005‐5p) to test the relationship between miRNAs and their target genes. The activity of the GUS testing assay indicated that miRNA could decrease the GUS activity by inhibiting the expression of their target genes. Collectively, this study provides a comprehensive analysis of transcriptome and small RNA sequencing of lotus root after inoculation with Fusarium oxysporum, and we identified candidate miRNAs and their target genes for breeding strategies of Nelumbo nucifera.
Automation, global value chains and functional specialization
Authors: Fontagné Lionel , Reshef Ariell , Santoni Gianluca , Vannelli Giulio 
Published: October 2023

AbstractWe study how technology adoption and changes in global value chain (GVC) integration jointly affect labor shares and business function specialization in a sample of 14 manufacturing industries in 14 European countries in 1999–2011. Increases in upstream, forward GVC integration directly reduce labor shares, mostly through reductions in fabrication, but also via other business functions. We do not find any direct effects of robot adoption; robotization affects labor only indirectly, by increasing upstream, forward GVC integration. In this sense robotization is “upstream‐biased”. Rapid robotization in China shaped robotization in Europe and, therefore, relative demand for labor there.
COVID‐19 non‐death loss and acceptance coping: A 3‐wave cross‐lagged panel analysis
Authors: English Alexander Scott , Sun Junjie , Xu Shuhong , Zheng Lu , Zhang Qionghan , Talhelm Thomas 
Published: October 2023

AbstractNumerous individuals have lost loved ones during the COVID‐19 pandemic while millions of others have also experienced ongoing pervasive non‐death loss. The understanding of how people deal with non‐death loss is still relatively limited. Incorporating theory of coping and loss, this study examines the reciprocal relationship between non‐death loss and acceptance coping. Based on the results of a cross‐lagged panel model involving 314 participants in China, we found that before the end of the zero‐Covid policy, non‐death loss at Time 1 predicted less acceptance coping at Time 2, but in the opening up stage in late 2022, non‐death loss at time 2 did not predict acceptance coping at time 3. The findings have significant implications for understanding the interplay between non‐death loss and acceptance coping and highlights abrupt psychological changes during the COVID‐19 pandemic.
Simultaneous realization of cadmium bioavailability reduction and spinach growth promotion in acidic soils with calcined oyster shells and dolomite
Authors: Fan Beibei , Li Xue , Fu Tianhong , Ding Shuai , Zhou Xue , Chen Qing , Peng Yutao 
Published: October 2023

AbstractCheap and widely available calcium‐based materials have gained popularity for remediating cadmium‐contaminated soils, but their potential to address cadmium (Cd) toxicity in acidic soils remains deeply understudied. The current study investigated the effects of calcined oyster shells (COS) and dolomite (DM), applied at a rate of 30 g kg−1, on Cd availability and its accumulation in spinach plants in acidic Cd‐contaminated soils (Cd concentration: 4.42 mg kg−1). Additionally, the influence of active aluminium (Al) on Cd bioavailability and plant Cd accumulation was examined. The application of COS and DM led to a reduction in diethylenetriaminepentaacetic acid extracted Cd (DTPA‐Cd) of 42.1% and 28.6%, respectively. Furthermore, the COS and DM positively increased soil pH (2.48 and 1.81 units), electrical conductivity (89.4% and 28.1%), organic matter content (17.2% and 11.9%) and available phosphorus (37.7% and 6.39%) and decreased soil exchangeable Al3+ (100% and 83.9%). As a result of amending with COS and DM, the Cd concentration (81.0%–82.9%) and bioaccumulation factor (78.8%–80.2%) in spinach plants were significantly decreased (p < .05). The presence of exchangeable Al3+ in the soil showed only a weak influence on plant Cd accumulation. The COS and DM also induced 8.65 times and 5.42 times greater spinach fresh matter yield compared with the control. In conclusion, the application of COS and DM as amendments in Cd‐polluted acidic soils holds great promise. The COS has greater prospects for immobilizing Cd, promoting plant biomass and producing plants with lesser Cd concentrations in acidic soils. This work offers a new strategy by adopting wide‐resource and cost‐effective mineral materials for sustainable environmental management.