bluuebunny/crossref_metadata_2025_split huggingface dataset:
Possibility of conjunction between altruism and egoism
Authors: Kago Kevin , Venkataraman Prabhu 
Published: September 2023

AbstractBoth altruism and egoism are two types of motivations for action. An altruistic action is performed to benefit the other, whereas egoistic action is performed to benefit oneself. The strict definition of altruism states that an action ceases to be altruistic if the actor receives the benefit of his action as a consequence directly or indirectly. On the other hand, egoism particularly psychological egoism presupposes that all actions, whether performed for oneself or the other, are always self-interested in nature and hence, egoistic. Given the dichotomous existence between the two types of actions, which on many occasions create conceptual misapprehension, a different alternative will be explored. The new inquiry will throw light on the possibility that we commit some kind of motivational extremism on a conceptual level. It will further be argued that altruism and egoism may have one singular motivational source through which various actions emerge.
Call to action: a five nations consensus on the use of intravenous zoledronate after hip fracture
Authors: Johansen Antony , Sahota Opinder , Dockery Frances , Black Alison J , MacLullich Alasdair M J , Javaid M Kassim , Ahern Emer , Gregson Celia L 
Published: September 2023

Abstract
Currently in the UK and Ireland, after a hip fracture most patients do not receive bone protection medication to reduce the risk of refracture. Yet randomised controlled trial data specifically examining patients with hip fracture have shown that intravenous zoledronate reduces refracture risk by a third. Despite this evidence, use of intravenous zoledronate is highly variable following a hip fracture; many hospitals are providing this treatment, whilst most are currently not. A range of clinical uncertainties, doubts over the evidence base and practical concerns are cited as reasons. This paper discusses these concerns and provides guidance from expert consensus, aiming to assist orthogeriatricians, pharmacists and health services managers establish local protocols to deliver this highly clinically and cost-effective treatment to patients before they leave hospital, in order to reduce costly re-fractures in this frail population.
Prevention of COVID-19 in workers: preparation, precaution, and protection
Authors: Agius Raymond M 
Published: September 2023

Abstract
In May 2023 the World Health Organization (WHO) Director General announced the “end” of the COVID-19 Public Health Emergency of International Concern. Although the scale of the pandemic was unprecedented in living memory, it had not been unforeseen. Previous outbreaks of viral respiratory disease have shown important lessons regarding the need to protect healthcare workers (HCW), and research has also been undertaken into the relative effectiveness of control measures and their resource implications. Relevant guidance for worker protection, including HCW protection, which existed at the onset of the COVID-19 pandemic was disregarded both at international and national governmental levels. In many countries there were significant systemic flaws in strategy, culture, and resource availability, and hence in overall preparedness. When the pandemic struck, many experts and organizations advocated a precautionary approach with regard to worker protection, consistent with good occupational hygiene science, practice, and standards. In many Asian countries, protective measures were relatively stringent. However, many workers were left unprotected especially as the WHO, the United States, the United Kingdom, and other governments did not pursue adequate COVID-19 protective measures at work. As the pandemic progressed, improvements in protection were patchy. A notable lack of protection arose from the underestimation of the contribution of aerosol exposure to infection risks, particularly among HCWs providing routine care of potentially infectious patients. A disciplined strategy of source control, pathway control (such as ventilation), and receptor control notably Respiratory Protective Equipment is needed, as well as worldwide vaccination, to contend with this pandemic. Control measures appropriate to the risk of infections transmitted through the air will remain necessary in the longer term, as well as adaptations in the workplace to take account of long-term COVID-19 morbidity and new work practices.
Buccal Fat Pad Excision for Facial Rejuvenation: The Relationship Between the Resected Position and Its Influence on Facial Shape and Volume
Authors: Kubo Takayuki 
Published: September 2023

Abstract

Background
To date, facelift surgery has been the most common choice for those seeking antiaging solutions. However, buccal fat pad (BFP) excision has also been utilized recently.

Objectives
An interrelation between the BFP, resection area, and its influence on facial shape and volume is scrutinized to achieve “tailor-made” outcomes in patients with BFP-related symptoms.

Methods
Patients were categorized into 2 groups: Type I with a bottom-heavy face and Type II with ptotic lower cheeks, typically seen in older people. The lower face was divided into upper and lower segments bilaterally. Then, the relationship between the resected position of the BFP and its influence on facial shape and volume was studied.

Results
BFP excision was performed for 133 patients (118 females and15 males) between May 2020 and June 2022. Sixty-one of these patients were categorized into Type I (39 patients) and Type II (22 patients) and were followed up for 12 months postoperatively. The volume of all lower facial segments decreased postoperatively in both types of patients. The variation rate of the upper segment volume in Type II patients was less than that in Type I patients. The results were consistent with a technique that did not remove large chunks of the BFP from the upper segment in Type II patients.

Conclusions
BFP excision is an effective facial rejuvenation treatment if proper candidates are selected. To improve the accuracy of BFP excision, the relationship between the resected position of the BFP and its influence on facial shape and volume should be well understood.

Level of Evidence: 3
The roles of different gene expression regulators in acoustic variation in the intermediate horseshoe bat revealed by long-read and short-read RNA sequencing data
Authors: Li Qianqian , Wu Jianyu , Mao Xiuguang 
Published: September 2023

Abstract
Gene expression changes contribute greatly to phenotypic variations in nature. Studying patterns of regulators of gene expression is important to fully understand the molecular mechanism underlying phenotypic variations. In horseshoe bats, the cochleae are finely tuned to echoes of call frequency. Here, using 2 recently diverged subspecies of the intermediate horseshoe bat (Rhinolophus affinis hainanus and R. a. himalayanus) with great acoustic variations as the system, we aim to explore relative roles of different regulators of gene expression (differential gene expression, alternative splicing (AS) and long non-coding RNAs (lncRNAs)) in phenotypic variation with a combination of Illumina short-read and Nanopore long-read RNA-seq data from the cochlea. Compared to R. a. hainanus, R. a. himalayanus exhibited much more upregulated differentially expressed genes (DEGs) and multiple of them may play important roles in the maintenance and damage repair of auditory hair cells. We identified 411 differentially expressed lncRNAs and their target DEGs upregulated in R. a. himalayanus were also mainly involved in a protective mechanism for auditory hair cells. Using 3 different methods of AS analysis, we identified several candidate alternatively spliced genes (ASGs) that expressed different isoforms which may be associated with acoustic divergence of the 2 subspecies. We observed significantly less overlap than expected between DEGs and ASGs, supporting complementary roles of differential gene expression and AS in generating phenotypic variations. Overall, our study highlights the importance of a combination of short-read and long-read RNA-seq data in examining the regulation of gene expression changes responsible for phenotypic variations.
A chromosome-level assembly supports genome-wide investigation of the DMRT gene family in the golden mussel (Limnoperna fortunei)
Authors: R. N. Ferreira João Gabriel , A. Americo Juliana , L. A. S. do Amaral Danielle , Sendim Fábio , R. da Cunha Yasmin ,   Tree of Life Programme, Blaxter Mark , Uliano-Silva Marcela , de F. Rebelo Mauro 
Published: September 2023

Abstract

Background
The golden mussel (Limnoperna fortunei) is a highly invasive species that causes environmental and socioeconomic losses in invaded areas. Reference genomes have proven to be a valuable resource for studying the biology of invasive species. While the current golden mussel genome has been useful for identifying new genes, its high fragmentation hinders some applications.

Findings
In this study, we provide the first chromosome-level reference genome for the golden mussel. The genome was built using PacBio HiFi, 10X, and Hi-C sequencing data. The final assembly contains 99.4% of its total length assembled to the 15 chromosomes of the species and a scaffold N50 of 97.05 Mb. A total of 34,862 protein-coding genes were predicted, of which 84.7% were functionally annotated. A significant (6.48%) proportion of the genome was found to be in a hemizygous state. Using the new genome, we have performed a genome-wide characterization of the Doublesex and Mab-3 related transcription factor gene family, which has been proposed as a target for population control strategies in other species.

Conclusions
From the applied research perspective, a higher-quality genome will support genome editing with the aim of developing biotechnology-based solutions to control invasion. From the basic research perspective, the new genome is a high-quality reference for molecular evolutionary studies of Mytilida and other Lophotrochozoa, and it may be used as a reference for future resequencing studies to assess genomic variation among different golden mussel populations, unveiling potential routes of dispersion and helping to establish better control policies.
Chromosome-level genome of the venomous snail Kalloconus canariensis: a valuable model for venomics and comparative genomics
Authors: Herráez-Pérez Ana , Pardos-Blas José Ramón , Afonso Carlos M L , Tenorio Manuel J , Zardoya Rafael 
Published: September 2023

Abstract

Background
Genomes are powerful resources to understand the evolutionary mechanisms underpinning the origin and diversification of the venoms of cone snails (Conidae: Caenogastropoda) and could aid in the development of novel drugs.

Findings
Here, we used PacBio continuous long reads and Omni-C data to assemble the chromosome-level genome of Kalloconus canariensis, a vermivorous cone endemic to the Canary Islands. The final genome size was 2.87 Gb, with a N50 of 79.75 Mb and 91% of the reads located into the 35 largest scaffolds. Up to 55.80% of the genome was annotated as repetitive regions, being class I of transposable elements (16.65%) predominant. The annotation estimated 34,287 gene models. Comparative analysis of this genome with the 2 cone snail genomes released to date (Dendroconus betulinus and Lautoconus ventricosus) revealed similar genome sizes and organization, although chromosome sizes tended to be shorter in K. canariensis. Phylogenetic relationships within subclass Caenogastropoda were recovered with strong statistical support. The family Conidae was recovered as a clade, with K. canariensis plus L. ventricosus sister to D. betulinus.

Conclusions
Despite the great diversity of cone snails (&gt;900 species) and their venoms (hundreds of peptides per species), only 2 recently reported genomes are available for the group. The high-quality chromosome-level assembly of K. canariensis will be a valuable reference for studying the origin and evolution of conotoxin genes as well as whole-genome duplication events during gastropod evolution.
Allele-specific regulatory effects on the pig transcriptome
Authors: Lin Yu , Li Jing , Chen Li , Bai Jingyi , Zhang Jiaman , Wang Yujie , Liu Pengliang , Long Keren , Ge Liangpeng , Jin Long , Gu Yiren , Li Mingzhou 
Published: September 2023

Abstract

Background
Allele-specific expression (ASE) refers to the preferential expression of one allele over the other and contributes to adaptive phenotypic plasticity. Here, we used a reciprocal cross-model between phenotypically divergent European Berkshire and Asian Tibetan pigs to characterize 2 ASE classes: imprinting (i.e., the unequal expression between parental alleles) and sequence dependent (i.e., unequal expression between breed-specific alleles). We examined 3 transcript types, including protein-coding genes (PCGs), long noncoding RNAs, and transcripts of unknown coding potential, across 7 representative somatic tissues from hybrid pigs generated by reciprocal crosses.

Results
We identified a total of 92 putative imprinted transcripts, 69 (75.00%) of which are described here for the first time. By combining the transcriptome from purebred Berkshire and Tibetan pigs, we found ∼6.59% of PCGs are differentially expressed between breeds that are regulated by trans-elements (e.g., transcriptional factors), while only ∼1.35% are attributable to cis (e.g., promoters). The higher prevalence of trans-PCGs indicates the dominated effects of trans-regulation in driving expression differences and shaping adaptive phenotypic plasticity between breeds, which were supported by functional enrichment analysis. We also found strong evidence that expression changes mediated by cis-effects were associated with accumulated variants in promoters.

Conclusions
Our study provides a comprehensive map of expression regulation that constitutes a valuable resource for the agricultural improvement of pig breeds.
Chromosome-level reference genome of tetraploid Isoetes sinensis provides insights into evolution and adaption of lycophytes
Authors: Cui Jinteng , Zhu Yunke , Du Hai , Liu Zhenhua , Shen Siqian , Wang Tongxin , Cui Wenwen , Zhang Rong , Jiang Sanjie , Wu Yanmin , Gu Xiaofeng , Yu Hao , Liang Zhe 
Published: September 2023

Abstract

Background
The Lycophyta species are the extant taxa most similar to early vascular plants that were once abundant on Earth. However, their distribution has greatly diminished. So far, the absence of chromosome-level assembled lycophyte genomes has hindered our understanding of evolution and environmental adaption of lycophytes.

Findings
We present the reference genome of the tetraploid aquatic quillwort, Isoetes sinensis, a lycophyte. This genome represents the first chromosome-level assembled genome of a tetraploid seed-free plant. Comparison of genomes between I. sinensis and Isoetestaiwanensis revealed conserved and different genomic features between diploid and polyploid lycophytes. Comparison of the I. sinensis genome with those of other species representing the evolutionary lineages of green plants revealed the inherited genetic tools for transcriptional regulation and most phytohormones in I. sinensis. The presence and absence of key genes related to development and stress responses provide insights into environmental adaption of lycophytes.

Conclusions
The high-quality reference genome and genomic analysis presented in this study are crucial for future genetic and environmental studies of not only I. sinensis but also other lycophytes.
Swedish Diplomats and Holocaust Knowledge
Authors: Bortz Olof 
Published: September 2023

Abstract
How did Swedish diplomats report the persecution and killing of European Jewry by Nazi Germany in the 1930s and during the Second World War? What did the Swedish Ministry for Foreign Affairs do with reports on the Holocaust during the war, and to what extent did such reports affect policy? This article shows that Swedish diplomats provided their superiors with reliable, if at times unverifiable, information about the different phases of the Holocaust from 1933 until the end of 1942, and argues that awareness of the transition from persecution to mass murder did not alter Swedish refugee policies. The author thus details the process whereby knowledge of the annihilation of the European Jews seeped out from eastern Europe by examining Swedish diplomatic reports on the Holocaust. Furthermore, he sheds new light on the history of Swedish refugee policies and Swedish German relations during the Nazi period.
“May God have mercy on his black soul”: Consul General Olof Lamm’s Private Diplomatic Efforts to Save Jews from Nazi Persecution
Authors: Rudberg Pontus 
Published: September 2023

Abstract
This article examines the private diplomatic efforts of Olof Lamm. A Swedish Jewish ex-diplomat and businessman, he used his personal network to protest against Nazi persecution of the Jews in Germany, and informally lobbied the United States to increase its immigration quotas. Shedding light on these informal back-channel diplomatic networks, the author provides examples of the attitudes and obstacles Lamm faced when dealing with individuals, and reveals how those he petitioned justified their defense of Nazi ideology and actions and their own restrictive immigration policies.
A chromosome-level genome assembly provides insights into Cornus wilsoniana evolution, oil biosynthesis, and floral bud development
Authors: He Zhenxiang , Chao Haoyu , Zhou Xinkai , Ni Qingyang , Hu Yueming , Yu Ranran , Wang Minghuai , Li Changzhu , Chen Jingzhen , Chen Yunzhu , Chen Yong , Cui Chunyi , Zhang Liangbo , Chen Ming , Chen Dijun 
Published: September 2023

Abstract
Cornus wilsoniana W. is a woody oil plant with high oil content and strong hypolipidemic effects, making it a valuable species for medicinal, landscaping, and ecological purposes in China. To advance genetic research on this species, we employed PacBio together with Hi-C data to create a draft genome assembly for C. wilsoniana. Based on an 11-chromosome anchored chromosome-level assembly, the estimated genome size was determined to be 843.51 Mb. The N50 contig size and N50 scaffold size were calculated to be 4.49 and 78.00 Mb, respectively. Furthermore, 30 474 protein-coding genes were annotated. Comparative genomics analysis revealed that C. wilsoniana diverged from its closest species ~12.46 million years ago (Mya). Furthermore, the divergence between Cornaceae and Nyssaceae occurred &gt;62.22 Mya. We also found evidence of whole-genome duplication events and whole-genome triplication γ, occurring at ~44.90 and 115.86 Mya. We further inferred the origins of chromosomes, which sheds light on the complex evolutionary history of the karyotype of C. wilsoniana. Through transcriptional and metabolic analysis, we identified two FAD2 homologous genes that may play a crucial role in controlling the oleic to linoleic acid ratio. We further investigated the correlation between metabolites and genes and identified 33 MADS-TF homologous genes that may affect flower morphology in C. wilsoniana. Overall, this study lays the groundwork for future research aimed at identifying the genetic basis of crucial traits in C. wilsoniana.
Establishing baselines for predicting change in ambient sound metrics, marine mammal, and vessel occurrence within a US offshore wind energy area
Authors: Van Parijs S M , DeAngelis A I , Aldrich T , Gordon R , Holdman A , McCordic J A , Mouy X , Rowell T J , Tennant S , Westell A , Davis G E 
Published: September 2023

Abstract
Evaluating potential impacts on marine animals or increased sound levels resulting from offshore wind energy construction requires the establishment of baseline data records from which to draw inference. This study provides 2 years of baseline data on cetacean species’ presence, vessel activity, and ambient sound levels in the southern New England wind energy area. With eight species/families present in the area for at least 9 months of the year, this area represents an important habitat for cetaceans. Most species showed seasonality, with peak daily presence in winter (harbour porpoise, North Atlantic right, fin, and humpback whales), summer (sperm whales), spring (sei whales), or spring and fall/autumn (minke whales). Delphinids were continuously present and blue whales present only in January. The endangered North Atlantic right whales were present year round with high presence in October through April. Daily vessel presence showed an increase from summer through fall/autumn. On average, ambient sound levels were lowest in summer and increased late 2021 through 2022 with most temporal variability occurring across lower frequencies. The area showed a complex soundscape with several species sharing time–frequency space as well as overlap of vessel noise with the communication range of all baleen whale species.
Reclaiming agency in the digital neighborhood: an ethnographic exploration of ethno-religious minority youths’ performances of the masculine self
Authors: De Leyn Tom 
Published: September 2023

AbstractSelf-presentation has been identified as a key practice within digital youth cultures. The scholarship on youths’ self-presentation has extensively investigated how young people negotiate affordances in ways that optimally support their transitions into adulthood. However, the scholarship’s focus on identity development and technological affordances risks constructing a homogeneous, de-contextualized, and media-centric representation of digital youth cultures. To unveil how self-presentation practices are embedded within a broader socio-cultural context, I conducted a 15-month hybrid ethnographic study with 23 ethno-religious minority young men living in Flanders, the Dutch-speaking part of Belgium. The observations illustrate that these young men attempt to reclaim agency over their identity representations by performing “masculine ideals” of the self in response to racialized discourses. Overall, the results underscore the necessity of adopting an intersectional perspective that considers the interplay between self-presentation on social media and the threats and opportunities within youths’ (digital) neighborhoods.
Antisemitism and the Left: On the Return of the Jewish Question
Authors: Carver Richard 
Published: September 2023

Abstract
This review considers Robert Fine and Philip Spencer’s Antisemitism and the Left: On the Return of the Jewish Question and explores the book’s key implications for human rights practitioners and their organizations. The review is one of three contributions to this 15th Anniversary Issue’s Review Section from members of the Journal of Human Rights Practice Editorial Team and Editorial Board—highlighting a book of particular significance to human rights practitioners and educators published between 2008 and 2023.