bluuebunny/crossref_metadata_2025_split huggingface dataset:
Validation of the 10‐Item Unilateral Vocal Fold Paralysis‐Handicap Index quality of life questionnaire
Authors: Hernández‐Sandemetrio Rosa , Oishi Natsuki , López‐Sánchez Isabel , García‐López Isabel , Zapater Enrique 
Published: November 2023

AbstractObjectivesTo validate and test the reliability of the 10‐Item Unilateral Vocal Fold Paralysis‐Voice Handicap Index (UVFP‐HI‐10) quality of life (QoL) questionnaire for patients with UVFP.DesignProspective describe study based on perceptive surveys.ParticipantsWe recruited 61 patients with UVFP and 53 healthy individuals comprised the control group.Main Outcome MeasuresBoth the patients and controls completed the UVFP‐HI‐10 questionnaire. A statistical analysis was performed to assess the internal consistency and validity of the survey. In addition, maximum phonation time (MPT) was used to objectively measure patient QoL.ResultsInternal consistency was high (α = .914) and the correlation with MPT was significant (rs = −0.722). The estimated marginal mean in the discriminant validity study was around seven times higher in the UVFP group compared to the controls. The UVFP‐HI‐10 cut‐off value was more than 0.9 and the sensitivity and specificity were more than 0.8.ConclusionsThe UVFP‐HI‐10 is a self‐administered patient‐reported outcome questionnaire with a high reliability and excellent criterion‐based validity. This questionnaire can be used to evaluate specific clinical complaints (e.g., vocalisation, swallowing, and breathing) in terms of their impact on QoL in patients with UVFP. Thus, its use is appropriate as a basic assessment tool as part of a specific UVFP treatment protocol.
Identification of the allergenic sensitizing potential of bisphenol A substitutes used in the industry
Authors: Mourot‐Bousquenaud Mélanie , Langonné Isabelle , Buchheit Maurane , Muller Samuel , Coiscaud Amélie , Mathiot Julianne , Jacquenet Sandrine , Battais Fabrice 
Published: November 2023

AbstractBackgroundBisphenol (BP‐)A is a chemical used in Europe to produce polycarbonate plastics and epoxy resin or as colour developer in thermal paper. Due to its toxicity, BPA presence was restricted by European regulations. Therefore, substitute chemicals are replacing BPA.ObjectiveTo assess the allergenic sensitizing potential of 27 substitutes to BPA used in the industry.MethodsThe expression of two costimulatory molecules and six cytokines were analysed by flow cytometry in mouse bone marrow‐derived dendritic cells (BMDCs) exposed to the chemicals.ResultsAll substances except one induced overexpression of at least one receptor and were thus identified as having allergenic sensitizing potential. Based on the BMDC model, they were classified as extreme (1 out of 27), strong (20 out of 27) and moderate (5 out of 27) sensitizers. BPA was classified as a moderate sensitizer and BPF was the only substitute classified as a non‐sensitizer. The more potent substitutes induced more than 2‐fold secretion of CCL3, CCL4 and/or CCL5 by dendritic cells.ConclusionMost of the BPA substitutes tested in this study have an allergenic sensitizing potential; 24 of them being more potent than BPA itself. Only BPE, BPF and 2,4‐BPS appeared to be weaker sensitizers than BPA.
The effect of virtual simulation technology applied to undergraduate teaching of periodontal probing
Authors: Wang Panpan , Wu Shiwen , Gao Li , Ning Yang , Zhang Chi , Pan Suxun , Zhao Chuanjiang 
Published: November 2023

AbstractIntroductionThe rise of virtual simulation technology and dental simulators has created a new pedagogical approach for undergraduate medical education. The purpose of this study is to evaluate the effect of virtual simulation (VS) technology on improving the students' comprehensive abilities in periodontal probing teaching in pre‐practicum periodontology, such as increasing the accuracy of probing, tactile perception and performance on force control.Materials and MethodsTwenty students were randomly selected among the fourth‐year students and equally divided into VS technology teaching group (VS group) and traditional teaching group (TT group) by drawing half lots. One day later, students were required to probe the periodontal pathology model. The consistency rate between PD measurements and PD reference values, time consumption and final exam scores were recorded and statistically analysed using an unpaired Student's t test and p < .05 was considered statistical significance. Finally, questionnaires relating to teaching methods evaluation and the fidelity of the digital VS training system were distributed to students and teachers.ResultsVS group had a significantly higher consistency rate (72.976 ± 6.811%) than TT group (64.107 ± 4.988%, p = .004). To specify, the difference of consistency rates between the two groups in posterior teeth was larger than anterior teeth. Similarly, a larger difference was also found in proximal surfaces compared with buccal‐lingual surfaces. As the pocket depth increased, the difference between the two groups increased too. These results indicated that VS is more efficient in complicated parts of periodontal probing teaching. In addition, students in VS group spent less time and gained a higher score than TT group (p < .05). The overall satisfaction rating in VS group was significantly higher than TT group. Lastly, teachers gave significant lower scores than students concerning the fidelity of VS system.ConclusionAlthough there are much to improve, VS technology has obvious advantages in periodontal probing teaching in pre‐practicum periodontology.
Welding hot cracking characteristics and fracture mechanisms of nickel‐based alloy NS1402 under different constraint conditions
Authors: Zhou Guangtao , Huang Tao , Zheng Huaibei , Wu Shikai , Song Wei , Zhang Hongtao , Berto Filippo 
Published: November 2023

AbstractThe influence of trace elements variation and constraint conditions on welding hot cracking was investigated to reveal the cracking characteristics of nickel‐based alloy NS1402. The fishbone tests and full restraint welding tests have been conducted to determine the cracking ratio. The mechanical and metallurgical fracture mechanisms were elaborated simultaneously. And the low‐melting point liquid membrane, which was a key metallurgical factor, was found in cracking fracture surface. Numerical simulations were conducted to illustrate the effects of transverse tensile stress/strain during welding processing. Results show that the liquid membranes were composed of FeNi, FeP, Co3Fe7, etc., indicating that liquid membranes were developed to higher melting point by Co3Fe7 eutectics due to the addition of Co, and it contributes to reducing cracking susceptibility of NS1402. The cracking was ductility‐dip cracking (DDC), which propagated in the forms of intergranular or transgranular fracture. Thus, adjusting element content and degrees of constraint could control the cracking tendency.
Not‐so‐simple nephrectomy: Comparative analysis of radical and simple nephrectomy in a high‐volume tertiary referral center
Authors: Papadopoulou Ariadni , Campain Nicholas , Abu‐Ghanem Yasmin , Shanmugathas Nimlan , Poullas Marios , Mumtaz Faiz , Barod Ravi , Tran Maxine , Bex Axel , Patki Prasad 
Published: November 2023

ObjectivesSimple nephrectomies can be challenging with significant morbidity. To prove the hypothesis of “not‐so‐simple” nephrectomy, we compared demographics, perioperative outcomes, and complications between simple and radical nephrectomy in a tertiary referral center.MethodsWe analyzed 473 consecutive radical nephrectomies (January 2018–October 2020) and simple nephrectomies (January 2016–October 2020). Univariate and multivariate analysis of perioperative outcomes utilized the Mann–Whitney U test, Chi‐squared test, Mantel–Haenszel test of trend, and multiple linear regression. Radical nephrectomies were classified in cT1, cT2a, and cT2b‐T3 subgroups and compared to simple nephrectomies. Minimally invasive and open techniques were compared between the two groups. Infected versus non‐infected simple nephrectomies were compared.ResultsA total of 344 radical and 129 simple nephrectomies were included. Simple nephrectomy was an independent predictor of increased operative time (p = 0.001), length of stay (p = 0.049), and postoperative complications (p < 0.001). Simple nephrectomies had higher operative time (p < 0.001), length of stay (p = 0.014), and postoperative morbidity (p < 0.001) than cT1 radical nephrectomies and significantly more Clavien 1–2 complications than cT2a radical nephrectomies (p = 0.001). The trend was similar in minimally invasive operations. However, conversion to open rates was not significantly different. Infected simple nephrectomies had increased operative time (p < 0.001), length of stay (p = 0.005), blood loss (p = 0.016), and intensive care stay (p = 0.019).ConclusionsPatients undergoing simple nephrectomy experienced increased operative time and morbidity. Simple nephrectomy carries higher morbidity than radical nephrectomy in tumors ≤10 cm. Robotic simple nephrectomies may reduce open conversion rates. Postoperative intensive care and enhanced recovery may be essential in simple nephrectomy planning with infected pathology.
RETRACTED: Effect of platelet‐rich plasma in treating patients with burn wounds: A meta‐analysis
Authors: Lin Chuanming , Xin Liuyan , Xie Shuiling 
Published: November 2023

AbstractA meta‐analysis was conducted to investigate the effects of platelet‐rich plasma (PRP) in the treatment of burn wounds and to provide a scientific basis for clinical drug therapy. We searched PubMed, Embase, Cochrane Library, China National Knowledge Infrastructure and Wanfang databases to identify randomised controlled trials (RCTs) on PRP in treating burn wounds, with the control group being treated with conventional treatments and the intervention group being treated with PRP alone or combined with PRP on the basis of the control group. The search duration was each database's inception to September 2023. The literature was screened, data were extracted and quality was assessed by two independent researchers. Data analysis was performed using the Review Manager 5.4 software. Eighteen RCTs comprising 1463 patients were included in the analysis. The meta‐analysis revealed that the application of PRP significantly improved the wound healing rate (standardised mean difference [SMD]: 1.11, 95% confidence interval [CI]: 0.54–1.67, p < 0.001), shortened wound healing time (SMD: −1.69, 95% CIs: −2.21 to −1.17, p < 0.001) and reduced the incidence of adverse events (7.03% vs. 18.93%, odds ratio [OR]: 0.32, 95% CI: 0.20–0.53, p < 0.001), and also significantly reduced patients' pain (SMD: −1.86, 95% CI: −2.47 to −1.25, p < 0.001) of burn patients when compared with the control group. This study showed that PRP is effective in repairing burn wounds, promoting wound healing, reducing the incidence of adverse events and reducing patient pain, making it worthy of clinical promotion and application.
Social connectedness and adolescent suicide risk
Authors: Arango Alejandra , Brent David , Grupp‐Phelan Jacqueline , Barney Bradley J. , Spirito Anthony , Mroczkowski Megan M. , Shenoi Rohit , Mahabee‐Gittens Melinda , Casper T. Charles , King Cheryl ,   in collaboration with the Pediatric Emergency Care Applied Research Network (PECARN)
Published: November 2023

BackgroundDespite evidence of the importance of interpersonal connectedness to our understanding of suicide risk, relatively little research has examined the protective and buffering effects of connectedness among adolescents. The aims of this study were to determine: (a) whether overall connectedness (composite of family, peer, and school) and specific domains of connectedness were related to a lower likelihood of suicide attempts, and (b) whether these factors buffer the prospective risk of suicide attempt for high‐risk subgroups (i.e., recent suicidal ideation and/or lifetime history of suicide attempt, peer victimization, or sexual and gender minority status).MethodsParticipants were 2,897 adolescents (64.7% biological female), ages 12 to 17 (M = 14.6, SD = 1.6), recruited in collaboration with the Pediatric Emergency Care Applied Research Network (PECARN) from 14 emergency departments for the Emergency Department Screen for Teens at Risk for Suicide Study (ED‐STARS). Suicide risk and protective factors were assessed at baseline; 3‐ and 6‐month follow‐ups were completed (79.5% retention). Multivariable logistic regressions were conducted, adjusting for established suicide risk factors.ResultsHigher overall connectedness and, specifically, school connectedness were associated with decreased likelihood of a suicide attempt across 6 months. Overall connectedness and connectedness domains did not function as buffers for future suicide attempts among certain high‐risk subgroups. The protective effect of overall connectedness was lower for youth with recent suicidal ideation or a suicide attempt history than for those without this history. Similarly, overall connectedness was protective for youth without peer victimization but not those with this history. Regarding specific domains, family connectedness was protective for youth without recent suicidal ideation or a suicide attempt history and peer connectedness was protective for youth without peer victimization but not youth with these histories.ConclusionsIn this large and geographically diverse sample, overall and school connectedness were related prospectively to lower likelihood of suicide attempts, and connectedness was more protective for youth not in certain high‐risk subgroups. Results inform preventive efforts aimed at improving youth connectedness and reducing suicide risk.
What Makes Politicians “Religious”? How Identity Congruence Shapes Religious Evaluations
Authors: Perry Samuel L. , Davis Joshua T. 
Published: November 2023

AbstractHow do Americans evaluate politicians’ religiosity? We theorize extra‐religious “identity congruence,” the perceived correspondence between others’ group identities and our own, will powerfully shape evaluations. We test this expectation using data from two large, nationally representative surveys that ask Americans to rate the religiosity of prominent politicians. Consistent with our theory, the strongest predictors of how Americans rate politicians’ religiosity are their congruence on party identification and ideological identity as well as expected alignments with racial identity and Christian nationalism. Respondents’ religious characteristics are relatively weak predictors. And these trends hold regardless of Americans’ knowledge of leaders’ professed religious identity. Patterns are consistent with our theory even when we split samples by party. When we compare ratings between politicians who are widely regarded as irreligious to those who are regarded as conventionally religious, partisan congruence and racial identity largely mitigate the religious advantage of the latter. Racial identity also moderates congruence on key factors. Finally, identity congruence on party, ideology, and Christian nationalism follows expected patterns even among secular Americans for whom “religious” less intuitively implies “my group.” In a time of growing identity‐alignment along partisan, ideological, racial, and religious lines, extra‐religious “identity congruence” powerfully shapes how Americans evaluate politicians’ religiosity.
Comparative analyses of micro‐ and macro‐scale surface structures in the convergent evolution of rain‐harvesting behaviour in lizards
Authors: Yenmiş M. , Ayaz D. , Sherbrooke W. C. , Veselý M. 
Published: November 2023

AbstractRain‐harvesting behaviour represents an adaptation for water collection that has evolved in some species of iguanian reptiles inhabiting arid environments. To date, such behaviour has been observed only in members of the families Agamidae and Phrynosomatidae. A common set of integumentary features characterizes these rain‐harvesting species, including scale surface microstructures (SSMs), capillary channels and hinge joints. The influence of variations in these features on rain‐harvesting has been a subject of discussion for many decades. Nevertheless, a comprehensive comparative study of similarities and differences between harvesting and non‐harvesting species on a broader scale remains lacking. In this study, we classify scale surface microstructures into three categories: large hexagons (SSM1), smaller nested hexagons (SSM2) and hinge pits (SSM2H). As the first two SSM types are widespread, they do not appear to be directly linked to the adaptation for rain‐harvesting. Conversely, the presence or absence of hinge pits distinguishes harvesters from non‐harvesters. Additionally, channel hierarchy, width and structure determine the effectiveness of the rain‐harvesting architecture. Only Moloch horridus exhibits distinct integumentary features in comparison to other agamids and rain‐harvesting species. Ancestral character state reconstruction suggests that rain‐harvesting behaviour was likely absent in the ancestor of Iguanians, even though overlapping scales and SSM1 were present. Our findings illustrate that rain‐harvesting species have independently converged upon similar structural solutions to address their water acquisition challenges, building upon shared pre‐existing features.
Annexin A1 may contribute to the morphological changes in podocytes by mediating endocytic vesicle fusion and transport via promotion of SNARE assembly in idiopathic membranous nephropathy
Authors: Song Lei , Shen Wen , Wang Le , Song Jianling , Tu Weiping , Ke Ben , Fang Xiangdong 
Published: November 2023

AbstractBackgroundAnnexin A1 is a membrane‐associated calcium‐binding protein that participates in the progression of many diseases by facilitating vesicle aggregation. It has been documented that reducing vesicle formation alleviates podocyte injury and albuminuria in idiopathic membranous nephropathy (IMN). However, the role of Annexin A1 (ANXA1) in IMN is unknown.MethodsElectron microscopy was used to observe the numbers of vesicles in podocytes. The expression of ANXA1 in IMN was investigated by bioinformatics analysis. We validated the hub genes with the Nephroseq V5 online tool and microarray data from the GEO. Immunohistochemical staining and qPCR were performed to measure gene and protein expression.ResultsThe numbers of vesicles in IMN podocytes were significantly increased. Bioinformatics analysis showed that ANXA1, one of the differentially expressed genes, was upregulated in glomeruli from IMN patients. In the validation database and dataset, we confirmed that ANXA1 expression was upregulated in the glomeruli of IMN patients. We revealed that the increased expression of ANXA1 was negatively correlated with the glomerular filtration rate (GFR) and proteinuria. Moreover, ANXA1 was enriched in the biological process of vesicle fusion, in which the expression of SNAREs and the SNARE complex was increased. Finally, the expression of ANXA1 and genes related to SNAREs and the SNARE complex was upregulated in glomeruli from IMN patients according to immunohistochemical staining and qPCR.ConclusionWe conclude that ANXA1 may mediate endocytic vesicle fusion and transport by promoting SNARE assembly, contributing to the morphological changes in podocytes and massive proteinuria in IMN.
Effective communication between nursing professionals and patients after the implementation of mask‐wearing requirements in the clinical setting: A cross‐sectional study
Authors: Gutiérrez‐Puertas Lorena , Márquez‐Hernández Verónica V. , Ortíz‐Rodríguez Blanca , Aguilera‐Manrique Gabriel , Gutiérrez‐Puertas Vanesa 
Published: November 2023

AbstractThis study aimed to evaluate staff nurses' perspectives on the use of face masks in effective communication and relationship management skills with patients in the hospital setting. The study surveyed registered nurses (RNs) who work with adult patients in different hospital units. An online survey was completed by RNs who were selected by convenience sampling. RNs' communication with patients was perceived as moderately affected by the use of face masks. Statistically significant differences were found when comparing communication with years of professional experience. Participants who had over 10 years of experience reported having greater difficulty in their communication with patients when using face masks. The effect of provider–patient relationship on effective nurse–patient face‐mask communication was statistically significant and negative. This study shows that some participants found face masks used in the clinical setting may affect nurse–patient communication, as well as the nurses' ability to manage their relationships with patients. The findings of this study support the need for targeted research into effective communication strategies when face mask use is needed in the healthcare setting.
The potential impact of periodontitis on cerebral small vessel disease
Authors: Bezerra Beatriz , Fisher Mark , Pirih Flavia Q. , Casarin Maísa 
Published: November 2023

AbstractCerebral small vessel disease (CSVD) is a term used to describe abnormalities in the intracranial microvasculature affecting small arteries, arterioles, capillaries, and venules. The etiology of these conditions is not fully understood but inflammation appears to play a significant role. Periodontal diseases have been associated with conditions such as stroke and dementia, which are clinical consequences of CSVD. Periodontitis is a highly prevalent chronic multifactorial inflammatory disease regulated by the host immune response against pathogenic bacterial colonization around the teeth. The inflammatory response and the microbial dysbiosis produce pro‐inflammatory cytokines that can reach the brain and promote local changes. This review will explore the potential association between periodontitis and CSVD by assessing the impact of periodontitis‐induced inflammation and periodontopathogenic bacteria on the underlying mechanisms leading to CSVD. Given the association of periodontitis with stroke and dementia, which are clinical features of CSVD, it may be possible to suggest a link with CSVD. Current evidence linking periodontitis with neuroimaging findings of CSVD enforces the possible link between these conditions.