bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health risk assessment of heavy metal pollution and its sources in agricultural soils near Hongfeng Lake in the mining area of Guizhou Province, China
Authors: Cui Wengang , Mei Yan , Liu Suihua , Zhang Xinding 
Published: November 2023

BackgroundAccelerated modern industrial processes, extensive use of pesticides and fertilizers and remaining issues of wastewater irrigation have led to an increasingly severe composite pollution of heavy metals in arable land. Soil contamination can cause significant damage to ecological environments and human health. Mineral resource mining can result in varying degrees of heavy metal pollution in surrounding water systems and soil. As a plateau lake, Hongfeng Lake has a fragile watershed ecosystem. Coupled with the rapid development of the current socio-economy and the ongoing activities of mining, urbanization and agricultural development, the water and soil environment of the lake and arable land are facing serious heavy metal pollution. Therefore, the situation warrants attention.MethodsThis study focused on characterizing soil types and conducted sampling and laboratory testing on the farmland soil in Hongfeng Lake. The integrated Nemero comprehensive pollution assessment and potential ecological pollution assessment methods were used to evaluate the heavy metal pollution status. The APCS-MLR model was employed to explore the sources of heavy metal pollution. In addition, the human health risk model was used to analyze the association between heavy metal content in cultivated land and human health risks.ResultsThe single-factor pollution of each element was ranked in descending order: Hg &gt; As &gt; Pb &gt; Cr &gt; Cd, with Hg being the main pollutant factor. The entire area was subjected to mild pollution according to the pollution index. Pollution source analysis indicated two main pollution sources. Hg, As, Pb and Cr pollution mainly resulted from Source 1 (industrial and natural activities), accounting for 71.99%, 51.57%, 67.39% and 68.36%, respectively. Cd pollution was mainly attributed to Source 2 (agricultural pollution source), contributing 84.12%. The health risk assessment model shows that heavy metals posed acceptable carcinogenic risks to humans rather than non-carcinogenic risks. As was the main non-carcinogenic risk factor, while Cr was the main carcinogenic risk factor, with higher risks in children than adults.ConclusionOur study identified the heavy metal pollution in farmland soil in Hongfeng Lake, evaluated and analyzed the pollution sources and identified the heavy metal elements in cultivated lands that have the greatest impact on human health risks. The aim of this study is to provide a scientific basis for soil heavy metal pollution control.
Impact of waterpipe smoking on the salivary microbiome
Authors: Senaratne Nikitha Lalindri Mareena , Chong Chun Wie , Yong Lim Shu , Yoke Ling Fong , Gopinath Divya 
Published: November 2023

BackgroundWhile oral mirobial dysbiosis due to tobacco smoking has been studied thoroughly, there is limited data on the effect of waterpipe smoking on the oral microbiome. This study aims to compare the salivary microbiome between waterpipe smokers and non-smokers.Materials and methodsUnstimulated saliva samples were collected from 60 participants, 30 smokers and 30 non-smokers in Kuala Lumpur and Klang Valley, Malaysia. DNA extraction was performed using the Qiagen DNA mini kit, and the 16S rRNA bacterial gene was amplified and sequenced using the Illumina MiSeq platform. Sequencing reads were processed using DADA2, and the alpha and beta diversity of the bacterial community was assessed. Significantly differentiated taxa were identified using LEfSe analysis, while differentially expressed pathways were identified using MaAsLin2.ResultsA significant compositional change (beta diversity) was detected between the two groups (PERMANOVA P &lt; 0.05). Specifically, the levels of phylum Firmicutes and genus Streptococcus were elevated in smokers, whereas phylum Proteobacteria and genus Haemophilus were depleted compared to non-smokers. At the species level, Streptococcus oralis, Streptococcus salivarius, and Streptococcus gingivalis were enriched in smokers. We observed significant differences in the abundance of thirty-seven microbial metabolic pathways between waterpipe smokers and non-smokers. The microbial pathways enriched in smokers were those implicated in polymer degradation and amino acid metabolism.ConclusionThe taxonomic and metabolic profile of the salivary microbiome in waterpipe smokers compared to healthy controls exhibited a paradigm shift, thus, implying an alteration in the homeostatic balance of the oral cavity posing unique challenges for oral health.
Severity of sleep apnea impairs adipose tissue insulin sensitivity in individuals with obesity and newly diagnosed obstructive sleep apnea
Authors: Rodrigues Sara , Bortolotto Luiz Aparecido , Beyl Robbie A. , Singh Prachi 
Published: November 2023

IntroductionObstructive sleep apnea (OSA) is a common sleep disorder associated with increased risk for the development of type 2 diabetes. While studies have examined the effects of sleep on whole-body insulin sensitivity, little is known about the effects of sleep on adipose tissue insulin sensitivity in patients with OSA. We analyzed if the severity of OSA, measured by apnea-hypopnea index (AHI), is associated with adipose tissue insulin sensitivity.MethodsWe examined the relationship between sleep parameters and adipose tissue insulin sensitivity in non-diabetic participants with obesity and newly diagnosed OSA who underwent overnight polysomnography and a 2 h oral glucose tolerance test during which circulating free fatty acids were measured. In total, 16 non-diabetic participants with obesity and newly diagnosed OSA (sex, 81.3% males; mean age, 50.9 ± 6.7 y; BMI, 36.5 ± 2.9 kg/m2; AHI, 43 ± 20 events/h) were included in the analysis.ResultsIn our study participants, AHI is inversely associated with free-fatty acid suppression during oral glucose challenge (R = −0.764, p = 0.001). This relationship persisted even after statistical adjustment for age (R = −0.769, p = 0.001), body mass index (R = −0.733, p = 0.002), waist-to-hip ratio (R = −0.741, p = 0.004), or percent body fat mass (R = −0.0529, p = 0.041). Furthermore, whole-body insulin sensitivity as determined by the Matsuda index was associated with percent REM sleep (R = 0.552, p = 0.027) but not AHI (R = −0.119, p = 0.660).ConclusionIn non-diabetic patients with OSA, the severity of sleep apnea is associated with adipose tissue insulin sensitivity but not whole-body insulin sensitivity. The impairments in adipose tissue insulin sensitivity may contribute to the development of type 2 diabetes.
Rare adrenal cavernous hemangioma: a case report highlighting diagnostic challenges
Authors: Antar Ryan Michael , Farag Christian Mark , Youssef Kirolos , Xu Vincent , Drouaud Arthur , Panitch Noah , Tariq Zoon , Alzeer Ali , Whalen Michael J. 
Published: November 2023

IntroductionAdrenal cavernous hemangiomas are rare benign vascular tumors that pose significant diagnostic challenges. Despite their benign nature, features overlapping with malignancies often complicate management decisions.Case presentationA 64-year-old male presented with a 4.4 cm necrotic left adrenal mass discovered incidentally on imaging. His medical history included papillary thyroid carcinoma, with subsequent thyroidectomy and radioactive iodine ablation. Evaluations for hiccups revealed multiple lung nodules, hypertrophic cardiomyopathy, and anemia. Given the patient’s previous cancer history, elevated aldosterone/renin ratio, and mass size, our multidisciplinary tumor board decided to proceed with a left adrenalectomy. Post-surgical pathology confirmed a diagnosis of adrenal cavernous hemangioma.ConclusionThe occurrence of ambiguous adrenal mass with other pathologies, such as our patient’s papillary thyroid carcinoma, complicates the diagnostic and therapeutic landscape. As demonstrated in our case, opting for surgery remains a viable solution for adrenal cavernous hemangiomas, especially for masses greater than 4 cm. Interdisciplinary collaboration, exemplified by our tumor board’s decision-making process, is crucial for optimal management. This case underscores the need for a multifaceted approach when confronting adrenal masses with such diagnostic ambiguity.
THE EFFECT OF GIVING BLACK GLUTINOUS BARTAPE SNACKS (ORIZA SATIVA GLUTINOSA ) ON THE INTENSITY LEVELS OF MENSTRUAL PAIN IN TEENAGE GIRL
Authors: Pasaribu Suar Saryati , Yulinda Yulinda 
Published: November 2023

Background: Dysmenorhoe is a situation in which a woman who wills or is experiencing menstruation feels pain. This cramps-like pain is felt in the lower abdomen, usually starting 24 hours before menstruation begins and lasts until the first 12 hours of menstruation, after which all the discomfort has disappeared. The cause is an imbalance of the hormone progesterone in the blood.Various treatment efforts have been made to alleviate these pain symptoms both pharmacologically and non-pharmacologically. Non-pharmacological treatments include giving warm compresses, massages, efflurage , distractions, physical exercise, and adequate rest or consuming foods that contain anthocyanins and flavonoids, one of which is the administration of Black Glutinous Tape.
Methods : The research method used is quasi-experimental research design with one group pretest-posttest. without control. The sample is 35 female teenage girls (ages 10-19 years) as many as 35 respondents, with a purposive sampling technique. Data analysis consisted of univariate analysis with (mean and standard deviation) and bivariate analysis using the Chi Square test.
Result : showed there was a decrease in the intensity of menstrual pain in female adolescents showed a decrease from pre-test 4.54 to 3.06 post test.
Statistical tests using the Wilcoxon sign rank test obtained a probability value of 0.000, smaller than alpha 0.05.
Conclusion : Giving black sticky rice tape to Teenage girls who reduce dysmenorrhea as a snack can reduce fatigue as a non- pharmacological alternative.
EFFECTS OF THYMUS TISSUE TRANSPLANTATION ON THE SURVIVAL OF MICE EXPOSED TO A LETHAL X-RAY DOSE
Authors: Куликов А.В. , Глазков А.А. , Куликов Д.А. , Гаврилюк В.Б. , Архипова Л.В. 
Published: November 2023

При радиационном облучении организма происходят процессы, сходные с теми, что характерны для естественного старения млекопитающих. Чаще всего это явление называют ускоренным старением. С помощью пересадки ткани тимуса удается добиться нормализации потребления пищи и воды, стабилизации набора массы тела, значительного увеличения продолжительности жизни экспериментальных животных даже при их летальном облучении.
During the radiation exposure of the body, processes similar to those characteristic of the natural aging of mammals occur. This phenomenon is most often referred to as accelerated aging. By transplanting the thymus tissue, it is possible to achieve a normalization of food and water consumption, a stabilization of weight gain, and a significant increase in the life expectancy of experimental animals, even after their lethal irradiation.
Development of a combined drainage system within the boundaries of the historical settlement of Samara
Authors: Стрелков А.К. , Шувалов М.В. , Палагин Е.Д. , Павлухин А.А. , Теплых С.Ю. 
Published: November 2023

Статья посвящена разработке комбинированной системы водоотведения в границах исторического поселения г. Самары. Рассмотрены вопросы централизованных ливневых систем водоотведения, сброс с которых осуществляется в Саратовское водохранилище. Особый интерес представляет историческая часть города, где находятся памятники архитектуры и истории, включая яйцевидный коллектор канализации, проложенный в начале ХХ века. Показано влияние снижения водопотребления на наполняемость трубопроводов и незагруженность городских очистных сооружений. Рассмотрен физико-химический состав поверхностных сточных вод, а также предельно допустимые концентрации загрязнений для реки Волги. Для корректировки данной ситуации предложено использование регулирующих (аккумулирующих) резервуаров для создания централизованной комбинированной системы водоотведения на десяти выпусках в реки Волгу и Самару. Разработана общая последовательность регулирования, очистки и сброса поверхностных сточных вод, которая представлена на горизонтальной схеме сброса поверхностных сточных вод. Возможность создания комбинированной системы водоотведения посредством применения регулирующих резервуаров на централизованной ливневой системе водоотведения для выпусков, находящихся в границах исторической части г. Самары, позволит решить проблему отвода поверхностного стока и частичной дополнительной загруженности городских очистных канализационных сооружений.
The paper dwells upon the development of a combined drainage system within the boundaries of the historical settlement of Samara. The issues of centralized storm sewer systems that discharge their effluents into the Saratov reservoir, are considered. Of particular interest is the historical part of the city where architectural and historical monuments are located including an egg-shaped sewer laid at the beginning of the twentieth century. The effect of water consumption reduction on the fill rate of the pipelines and underloading of the municipal wastewater treatment facilities is shown. The physicochemical composition of surface runoff, as well as maximum permissible concentrations for the Volga River are considered. To correct the situation, using regulating (storage) tanks is proposed to develop a centralized combined drainage system at ten outfalls into the Volga and Samara rivers. A general sequence for the regulation, treatment and discharge of surface runoff has been developed presented in the horizontal diagram of the discharge of surface runoff. Possible development of a combined drainage system with the use of regulating tanks in a public storm sewer for the outfalls located within the boundaries of the historical part of Samara will solve the problem of removing surface runoff and provide for the partial additional workload on the municipal wastewater treatment facilities.
A Review Report on Big Data Analytics
Authors: Berlas Faizan 
Published: November 2023

<p>The emergence of modern information systems, social media platforms, Internet of Things (IoT) devices, web and mobile applications, and other new technologies have resulted in the generation of huge amounts of data. Big data refers to extensive and diverse datasets that are generated from a wide range of sources and pose challenges in processing and analyzing using traditional data tools. Software systems that are designed to handle large and complex datasets are known as big data software systems. These are a collection of tools, technologies, and platforms designed to handle, process, analyze, and extract insights from big data. This research paper presents a comprehensive review of various aspects of big data software engineering, development tools, literature reviews, techniques, and terminologies. It offers valuable insights into the significant areas of big data that have undergone extensive research in recent years. By providing a thorough understanding of big data software systems, the paper serves as a valuable resource for researchers venturing into the realm of big data and seeking potential avenues for future research. </p>
ASSISTÊNCIA AO IDOSO: A IMPORTÂNCIA DO CUIDADO HUMANIZADO DA ENFERMAGEM.
Authors: Lima Luana Paola Borges de , Mandoti Isabelle Laís , Ali Sumaya Fouad , Souza Fabiana Mikaele de , Weizemann Luana Patricia , Busetti Ityara Cristina 
Published: November 2023

Introdução: O envelhecimento é um processo natural que envolve mudanças físicas, emocionais e sociais. O aumento da população idosa no Brasil é um fenômeno evidente, tornando crucial a compreensão desse processo e a promoção de um envelhecimento saudável. Objetivo: Identificar a importância da assistência humanizada aos idosos, visando aprimorar o atendimento a essa população. Metodologia: Revisão do tipo narrativa, de caráter descritivo exploratório, utilizando a Biblioteca Virtual da Saúde para buscar artigos nos últimos cinco anos (2018-2022) relacionados a assistência ao idoso: a importância do cuidado humanizado da enfermagem. Resultados: Foram encontrados 14 artigos, dos quais 4 atenderam aos critérios de inclusão. Os artigos analisados destacam a promoção do envelhecimento ativo e saudável e ressaltam ainda, a importância da assistência à pessoa idosa. Discussão: As adversidades do envelhecimento, o cuidado do enfermeiro e as práticas de enfermagem para a promoção do envelhecimento ativo e saudável. Conclusão: Um dos papeis da enfermagem diante do cuidado humanizado da pessoa idosa deve ser a execução de atitudes que visam apoiar e tratar este paciente de maneira particular, o atendimento humanizado caracteriza-se por atenção, diálogo e uma escuta qualificada entre o profissional e o usuário valorizando-o, abrangendo de forma integral, holística e humana.
Continuous Sciatic Popliteal Block as Postoperative Pain Management in Patient with Closed Fracture Right Ankle Undergo ORIF PS Surgery
Authors: Santo Budi , Tjokorda Gde Agung Senapathi  
Published: November 2023

Introduction: Currently, foot and ankle surgeries are on the rise, and a significant challenge in these cases is the intense post-operative pain that arises from early patient mobilization. Continuous popliteal sciatic block have emerged as a solution, effectively alleviating pain from the intra-operative to post-operative stages for patients undergoing foot and ankle surgery. According to a study conducted by Ding and colleagues, continuous blocks have proven to be more effective than a single injection in providing pain relief.
Case presentation: A 24-year-old woman diagnosed with a closed fracture of her right ankle is scheduled for open reduction internal fixation (ORIF) with a plate and screws for her right ankle. The patient has an American Society of Anesthesiologists (ASA) physical status of III and is dealing with grade II obesity. A continuous popliteal sciatic block was performed on the patient under ultrasound guidance, with the catheter tip placed outside the perineural area. Postoperatively, the patient received pain management through a regimen of 0.1% bupivacaine, 20 ml volume, administered every 4 hours. Remarkably, the patient experienced minimal pain until the 2nd day after surgery and was discharged home.
Conclusion: The continuous popliteal sciatic block is a regional anesthetic method that offers potent pain relief for patients undergoing foot and ankle surgery. Extensive evidence supports its effectiveness and safety during administration, making it a reliable choice for pain management in these procedures.
Sirenomelia: Relato De Caso E Revisão Da Literatura
Authors: Hiar Leticia Sinatora , Neto Attilio Brisighelli 
Published: November 2023

Introdução: A sirenomelia é uma condição caracterizada pelo desenvolvimento anormal do corpo caudal de um feto, com fusão parcial ou completa da extremidade inferior, sendo também conhecida como Síndrome da Sereia. A anomalia é uma malformação grave multissistêmica, geralmente envolvendo os sistemas gastrointestinal, geniturinário, cardiovascular e musculoesquelético. A causa exata da sirenomelia é desconhecida, e acredita-se que fatores ambientais e genéticos possam desempenhar um papel no desenvolvimento da referida anomalia. O prognóstico da sirenomelia é ruim, com uma sobrevida média de menos de uma semana e mais da metade dos casos terminam em natimortos.
Objetivo: Relatar um caso de sirenomelia atendido em nosso Serviço.
Método: Trata-se do relato do caso de uma gestante atendida no Serviço de Ginecologia e Obstetrícia do Hospital Universitário São Francisco na Providência de Deus – HUSF, localizado na cidade de Bragança Paulista - SP.
Relato do Caso: Paciente primigesta, 17 anos, encaminhada ao Serviço de Medicina Fetal após a realização de ultrassonografia morfológica durante a gravidez que demonstrou múltiplas malformações, incluindo agenesia renal e oligoâmnio severo. A criança nasceu prematura e com sirenomelia, falecendo quatro horas após o parto. Análises da placenta e do cordão umbilical revelaram anormalidades na implantação do feto, além de uma artéria umbilical única.
Conclusão: A sirenomelia é uma anomalia congênita rara e fatal, caracterizada pela fusão das extremidades inferiores, frequentemente associada a malformações adicionais. Sua etiologia é pouco compreendida e os possíveis fatores de risco incluem diabetes materno, exposição a fármacos teratogênicos, suscetibilidade genética, infecções e idade materna. Com base no caso descrito, sugere-se que a realização de ultrassonografia é crucial para o diagnóstico precoce e tomada de decisão frente a casos de sirenomelia. No mais, a conscientização sobre a prevenção da gravidez na adolescência e o controle da glicemia em mães diabéticas são essenciais para reduzir a incidência da síndrome.
Giant Outer Transiting Exoplanet Mass (GOT ’EM) Survey. III. Recovery and Confirmation of a Temperate, Mildly Eccentric, Single-transit Jupiter Orbiting TOI-2010
Authors: Mann Christopher R. , Dalba Paul A. , Lafrenière David , Fulton Benjamin J. , Hébrard Guillaume , Boisse Isabelle , Dalal Shweta , Deleuil Magali , Delfosse Xavier , Demangeon Olivier , Forveille Thierry , Heidari Neda , Kiefer Flavien , Martioli Eder , Moutou Claire , Endl Michael , Cochran William D. , MacQueen Phillip , Marchis Franck , Dragomir Diana , Gupta Arvind F. , Feliz Dax L. , Nicholson Belinda A. , Ziegler Carl , Villanueva Steven , Rowe Jason , Talens Geert Jan , Thorngren Daniel , LaCourse Daryll , Jacobs Tom , Howard Andrew W. , Bieryla Allyson , Latham David W. , Rabus Markus , Fetherolf Tara , Hellier Coel , Howell Steve B. , Plavchan Peter , Reefe Michael , Combs Deven , Bowen Michael , Wittrock Justin , Ricker George R. , Seager S. , Winn Joshua N. , Jenkins Jon M. , Barclay Thomas , Watanabe David , Collins Karen A. , Eastman Jason D. , Ting Eric B. 
Published: November 2023

Abstract
Large-scale exoplanet surveys like the Transiting Exoplanet Survey Satellite (TESS) mission are powerful tools for discovering large numbers of exoplanet candidates. Single-transit events are commonplace within the resulting candidate list due to the unavoidable limitation of the observing baseline. These single-transit planets often remain unverified due to their unknown orbital periods and consequent difficulty in scheduling follow-up observations. In some cases, radial velocity (RV) follow up can constrain the period enough to enable a future targeted transit detection. We present the confirmation of one such planet: TOI-2010 b. Nearly three years of RV coverage determined the period to a level where a broad window search could be undertaken with the Near-Earth Object Surveillance Satellite, detecting an additional transit. An additional detection in a much later TESS sector solidified our final parameter estimation. We find TOI-2010 b to be a Jovian planet (M

P
= 1.29 M
Jup, R

P
= 1.05 R
Jup) on a mildly eccentric orbit (e = 0.21) with a period of P = 141.83403 days. Assuming a simple model with no albedo and perfect heat redistribution, the equilibrium temperature ranges from about 360 to 450 K from apastron to periastron. Its wide orbit and bright host star (V = 9.85) make TOI-2010 b a valuable test bed for future low-insolation atmospheric analysis.