bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predictors of shunt insertion in patients with aneurysmal subarachnoid haemorrhage—a single-centre retrospective analysis
Authors: Capion Tenna , Lilja-Cyron Alexander , Olsen Markus Harboe , Møller Kirsten , Juhler Marianne , Mathiesen Tiit 
Published: January 2024

Abstract

Background
No standard has been established regarding timing and choice of strategy for discontinuation of external ventricular drainage (EVD) in patients with aneurysmal subarachnoid haemorrhage (aSAH), and little is known about the importance of clinical variables. A proportion of the patients who initially pass their discontinuation attempt return with delayed hydrocephalus and the need of a permanent shunt. Early differentiation between patients who need a shunt and those who do not would facilitate care.
We conducted a retrospective analysis on patients with aSAH and an EVD to search significant differences in treatment and clinical variables between patients who received a permanent shunt during initial hospitalization or after readmission, and those who never received a shunt.

Methods
We included 183 patients with aSAH who received an EVD over a 4-year period between 2015 and 2018 and divided them into three groups: those who received a shunt during primary admission, those who were readmitted for delayed hydrocephalus and received a shunt, and those who never needed a shunt. Between these groups, we compared selected clinical variables as well as outcome at discharge and after 6 months. Additionally, we assessed the ability of a shunt dependency score (SDASH) to predict the need for permanent drainage in the patients.

Results
Of 183 included patients, 108 (59%) ultimately received a ventriculoperitoneal (VP) shunt. Of these, 89 (82%) failed discontinuation during the primary admission and received a permanent shunt before discharge from the neurosurgical department. The remaining 19 (18%) were discharged after successful discontinuation, but subsequently developed delayed hydrocephalus and were admitted for shunt placement a median of 39 (range: 18–235) days after ictus. Ninety-four patients were discharged after successful discontinuation of the EVD, consisting of those who never developed the need for a permanent shunt and the 19 who were readmitted with delayed hydrocephalus, corresponding to a 20% (19/94) readmittance rate. Clinical variables such as drainage volume or discontinuation strategy did not differ across the three groups of patients. The SDASH score failed to provide any clinically useful information regarding prediction of shunt placement.

Conclusion
In this study, clinical variables including use of the predictive score SDASH predicted neither the overall need for nor the timing of shunt placement after aSAH. The homogeneous distribution of data between the three different groups renders strong independent clinical predictive factors unlikely. Thus, attempts to predict a permanent shunt requirement from these variables may be futile in these patients.
Predictive value of facial motor–evoked potential and electromyography for facial motor function in vestibular schwannoma surgery
Authors: Machetanz Kathrin , Roegele Martin , Liebsch Marina , Oberle Linda , Weinbrenner Eliane , Gorbachuk Mykola , Wang Sophie S. , Tatagiba Marcos , Naros Georgios 
Published: January 2024

Abstract

Purpose
Intraoperative neuromonitoring (IONM) aims to preserve facial nerve (FN) function during vestibular schwannoma (VS) surgery. However, current techniques such as facial nerve motor evoked potentials (FNMEP) or electromyography (fEMG) alone are limited in predicting postoperative facial palsy (FP). The objective of this study was to analyze a compound fEMG/FNMEP approach.

Methods
Intraoperative FNMEP amplitude and the occurrence of fEMG-based A-trains were prospectively determined for the orbicularis oris (ORI) and oculi (OCU) muscle in 322 VS patients. Sensitivity and specificity of techniques to predict postoperative FN function were calculated. Confounding factors as tumor size, volume of intracranial air, or IONM duration were analyzed.

Results
A relevant immediate postoperative FP was captured in 105/322 patients with a significant higher risk in large VS. While fEMG demonstrated a high sensitivity (77% and 86% immediately and 15 month postoperative, respectively) for identifying relevant FP, specificity was low. In contrast, FNMEP have a significantly higher specificity of 80.8% for predicting postoperative FP, whereas the sensitivity is low. A retrospective combination of techniques demonstrated still an incorrect prediction of FP in ~ 1/3 of patients.

Conclusions
FNMEP and fEMG differ in sensitivity and specificity to predict postoperative FP. Although a combination of IONM techniques during VS surgery may improve prediction of FN function, current techniques are still inaccurate. Further development is necessary to improve IONM approaches for FP prediction.
Can the native crab Thalamita danae be an effective biological control agent of the invasive mussel Xenostrobus securis in Hong Kong?
Authors: Au Ming Fung Franco , Hui Tin Yan , Williams Gray A. 
Published: January 2024

AbstractLocal predators are often considered effective and environmentally-friendly control agents to limit invasive species. Such biological control, however, depends on both the predator prey preferences and performances, which are in turn affected by variations in the physical environment. This study investigated the predation of the swimming crab Thalamita danae on the invasive mussel Xenostrobus securis under different salinity and thermal conditions. Xenostrobus securis, which is native to Australia, has spread to Hong Kong since the last decade, causing adverse ecological and economic impacts. Laboratory experiments evaluated the prey preferences and feeding behaviours of the crab on both the native mussel Brachidontes variabilis and the invasive X. securis under different typical salinities (15, 25, and 35‰) and temperatures (22 and 28 °C). The crab did not show clear preference toward either the invasive or the native mussels. Although the shell morphology of the invasive mussels lowered handling time as compared to the native mussels, the crab consumption rate was similar between the mussel species. The survival and predation rate of the crab were, however, substantially reduced under low salinities (< 15‰) where X. securis could be found. Thalamita danae, therefore, is a potential predator of X. securis, but such predation is only possible under normal, oceanic conditions. In hyposaline, estuarine/ freshwater environments where X. securis can survive, however, T. danae performs poorly and, as a result, such physical conditions may represent a predator refuge for the mussels to invade local ecosystems.
Improving Cointegration-Based Pairs Trading Strategy with Asymptotic Analyses and Convergence Rate Filters
Authors: Ti Yen-Wu , Dai Tian-Shyr , Wang Kuan-Lun , Chang Hao-Han , Sun You-Jia 
Published: January 2024

AbstractA pairs trading strategy (PTS) constructs a mean-reverting portfolio whose logarithmic value moves back and forth around a mean price level. It makes profits by longing (or shorting) the portfolio when it is underpriced (overpriced) and closing the portfolio when its value converges to the mean price level. The cointegration-based PTS literature uses the historical sample mean and variance to establish their open/close thresholds, which results in bias thresholds and less converged trades. We derive the asymptotic mean around which the portfolio value oscillates. Revised open/close thresholds determined by our asymptotic mean and standard derivations significantly improve PTS performance. The derivations of asymptotic means can be extended to construct a convergence rate filter mechanism to remove stock pairs that are unlikely to be profitable from trading to further reduce trading risks. Moreover, the PTS literature oversimplifies the joint problem of examining a stock pair’s cointegration property and selecting the fittest vector error correction model (VECM). We propose a two-step model selection procedure to determine the cointegration rank and the fittest VECM via the trace and likelihood ratio tests. We also derive an approximate simple integral trading volume ratio to meet no-odd-lot trading constraints. Experiments from Yuanta/P-shares Taiwan Top 50 Exchange Traded Fund and Yuanta/P-shares Taiwan Mid-Cap 100 Exchange Traded Fund constituent stock tick-by-tick backtesting during 2015–2018 show remarkable improvements by adopting our approaches.
Wetland geomorphology and tidal hydrodynamics drive fine-scale fish community composition and abundance
Authors: Clause Justin K. , Farruggia Mary Jade , Feyrer Frederick , Young Matthew J. 
Published: January 2024

AbstractEffective restoration of tidal wetlands for fish communities requires clear goals and mechanistic understanding of the ecosystem drivers which affect fish distribution and abundance. We examined fish community responses to abiotic habitat features in two adjacent but dissimilar freshwater tidal wetlands in the Sacramento-San Joaquin Delta, CA, USA, each of which represents a potential restoration configuration. The first wetland was characterized by a broad, intertidal basin with relatively high hydrodynamic exchange with surrounding waterways. The second wetland was characterized by a dendritic network of shallow subtidal channels with relatively low hydrodynamic exchange. Fish community composition significantly differed between the two wetlands, based on permutational analysis of variance. Fish abundance within and among the two wetlands was also highly affected by specific geomorphic and hydrodynamic characteristics: distance from connection with the main external waterway, bed elevation, and water surface elevation. The physical configuration of a restored tidal wetland, in conjunction with the way tides move across the restored landscape, has strong implications for local fishes. Manipulating these elements to create a landscape mosaic of habitat configurations can be an effective tool for targeting desired restoration outcomes, such as specific fish communities or target fish densities.
When is Learning “Effortful”? Scrutinizing the Concept of Mental Effort in Cognitively Oriented Research from a Motivational Perspective
Authors: Grund Axel , Fries Stefan , Nückles Matthias , Renkl Alexander , Roelle Julian 
Published: January 2024

AbstractIn the context of instructional design and self-regulated learning research, the notion of mental effort allocation, monitoring, and control has gained increasing attention. Bringing together a cognitive perspective, focusing on Cognitive Load Theory, and a motivational perspective, merging central accounts from Situated Expectancy Value Theory and Self-Determination Theory, we plea for a three-fold conception of effort that clearly distinguishes the different psychological sources of experiencing and allocating effort in learning environments: effort-by-complexity, effort-by-need frustration, and effort-by-allocation. Such a detailed conception has important implications for how effort should be studied and how it can be influenced by instructional support or by the learning individual itself. A first conclusion we draw is that cognitively oriented research needs to be careful when taking students’ self-reports on the “effortfulness” of a task as an indication of the object-level cognitive requirements of the task, as such appraisals may also reflect the affective-emotional requirements of task execution as well as motivational beliefs regarding the likelihood of success and meaningfulness of a task. A second conclusion is that instructional procedures rooted in cognition-oriented theory ideally are complemented by motivation theory to support student learning optimally.
Improving density and strength-to-ductility ratio of a 3D-printed Al–Si alloy by high-pressure torsion
Authors: Muñoz Jairo Alberto , Komissarov Alexander , Avalos Martina , Bolmaro Raúl E. , Zhu Yuntian , Cabrera José María 
Published: January 2024

AbstractGood combination of strength and ductility in metallic materials is always desired. To this end, this study assesses the combination of two modern manufacturing processes, namely additive manufacturing (AM) and severe plastic deformation, for an AlSi11Cu alloy. Laser powder bed fusion (L-PBF) produced an alloy with spherical pores with an average size of 42 μm, representing a volume fraction lower than 0.15%. At the mesoscale, the alloy showed a cellular microstructure made up of Al cells and Si-rich boundaries with an average size of 0.69 µm, which were broken down by the high-pressure torsion (HPT) process into ultrafine particles smaller than 0.41 µm. The HPT process transformed the columnar grains of the as-built material into ultrafine-grained grains around the disk edges, while the central zone conserved the as-built characteristics for a number of HPT turns smaller than ¼. HPT processing at room and warm temperatures gave rise to strength–ductility improvements with yield strengths and elongations larger than 400 MPa and 10%, respectively. The good strength–ductility trade-off was related to the porosity decrease, the breakdown of the interconnected network into particles of ultrafine size, the grain size reduction due to the dislocation density increase, and the formation of precipitates and Si-rich particles of different sizes. Thus, AM and HPT improved the grain boundary and precipitation strengthening, giving rise to an Al–Si alloy with superior mechanical properties.
Graphical abstract
A non-invasive continuous and real-time volumetric monitoring in spontaneous breathing subjects based on bioimpedance—ExSpiron®Xi: a validation study in healthy volunteers
Authors: Gatti Stefano , Rezoagli Emanuele , Madotto Fabiana , Foti Giuseppe , Bellani Giacomo 
Published: January 2024

AbstractTidal volume (TV) monitoring breath-by-breath is not available at bedside in non-intubated patients. However, TV monitoring may be useful to evaluate the work of breathing. A non-invasive device based on bioimpedance provides continuous and real-time volumetric tidal estimation during spontaneous breathing. We performed a prospective study in healthy volunteers aimed at evaluating the accuracy, the precision and the trending ability of measurements of ExSpiron®Xi as compared with the gold standard (i.e. spirometry). Further, we explored whether the differences between the 2 devices would be improved by the calibration of ExSpiron®Xi with a pre-determined tidal volume. Analysis accounted for the repeated nature of measurements within each subject. We enrolled 13 healthy volunteers, including 5 men and 8 women. Tidal volume, TV/ideal body weight (IBW) and respiratory rate (RR) measured with spirometer (TVSpirometer) and with ExSpiron®Xi (TVExSpiron) showed a robust correlation, while minute ventilation (MV) showed a weak correlation, in both non/calibrated and calibrated steps. The analysis of the agreement showed that non-calibrated TVExSpiron underestimated TVspirometer, while in the calibrated steps, TVExSpiron overestimated TVspirometer. The calibration procedure did not reduce the average absolute difference (error) between TVSpirometer and TVExSpiron. This happened similarly for TV/IBW and MV, while RR showed high accuracy and precision. The trending ability was excellent for TV, TV/IBW and RR. The concordance rate (CR) was >95% in both calibrated and non-calibrated measurements. The trending ability of minute ventilation was limited. Absolute error for both calibrated and not calibrated values of TV, TV/IBW and MV accounting for repeated measurements was variably associated with BMI, height and smoking status. Conclusions: Non-invasive TV, TV/IBW and RR estimation by ExSpiron®Xi was strongly correlated with tidal ventilation according to the gold standard spirometer technique. This data was not confirmed for MV. The calibration of the device did not improve its performance. Although the accuracy of ExSpiron®Xi was mild and the precision was limited for TV, TV/IBW and MV, the trending ability of the device was strong specifically for TV, TV/IBW and RR. This makes ExSpiron®Xi a non-invasive monitoring system that may detect real-time tidal volume ventilation changes and then suggest the need to better optimize the patient ventilatory support.
Exploring the Impact of Safer Sports Betting Promotion on Social Media: An Experimental Study
Authors: Houghton Scott , Moss Mark 
Published: January 2024

AbstractThe current study assessed the effectiveness of delivering safer gambling messaging to regular sport bettors on social media. It also assessed whether the content of the message impacted message effectiveness. A 3 × 2 mixed factorial design was employed, with 281 participants randomly assigned to follow one of three Twitter accounts. The accounts either sent out informational messages, self-appraisal messages or emotional self-efficacy messages. Participants reported betting behaviour from the two weeks prior to following the accounts, in addition to during the two-week intervention period, using information from their online gambling accounts. Participants reported readiness to change gambling behaviour pre and post the two-week intervention period. A significant main effect of intervention stage highlighted reductions in betting behaviour and increased readiness to change behaviour. However, there was no significant main effect of condition and no significant interaction between intervention stage and condition upon betting behaviour or readiness to change. The findings suggest receiving safer gambling messages on social media may lead to a reduction in betting behaviour. However, similar reductions in behaviour were observed in the experimental and control conditions. Further research is needed to clarify whether changes in behaviour observed in the current study would extend over a longer period of time.
Blood flow rate to the femur of extinct kangaroos implies a higher locomotor intensity compared to living hopping macropods
Authors: Hu Qiaohui , Seymour Roger S. , Snelling Edward P. , Wells Rod T. 
Published: January 2024

AbstractThe stocky skeletons and post-cranial anatomy of many extinct kangaroos indicate that they might have engaged in varied locomotor behaviors, rather than bipedal hopping, as their primary mode of locomotion. This study investigates support for this idea by estimating femoral bone perfusion, which is a correlate of locomotor intensity, in extinct kangaroos compared to living hopping species. Femur blood flow rates can be estimated from the sizes of nutrient foramina on the femur shaft of living and extinct species, without preservation of soft tissue. Estimated femur blood flow rates among the extinct Macropus, Protemnodon and Sthenurinae (Sthenurus, Simosthenurus and Procoptodon) are not significantly different from one another but are significantly greater than in living hopping macropods after accounting for the effect of body mass, consistent with their purportedly different locomotor style. The giant sthenurines have more robust femora than extrapolated from data of living hopping macropods, possibly due to the larger sthenurines requiring relatively stronger leg bones to support their heavier body weights, especially if loaded onto a single limb during bipedal striding.
Two New Sub-GLEs Found in Data of Neutron Monitors at South Pole and Vostok: On 09 June 1968 and 27 February 1969
Authors: Poluianov Stepan , Batalla Oscar , Mishev Alexander , Koldobskiy Sergey , Usoskin Ilya 
Published: January 2024

AbstractIntense solar energetic particle (SEP) events can be observed by neutron monitors (NMs) as so-called ground-level enhancements (GLEs). High-altitude polar NMs have high sensitivity for SEP due to the reduced atmospheric energy cutoff and very low geomagnetic rigidity cutoff compared to other NMs. There is a special class of sub-GLE events, viz. events that are weaker than standard GLEs and can only be observed by high-altitude polar NMs. So far, only one sub-GLE and three candidates are known, all in the period 2012 – 2015. In this work, we inspected the period from March 1964 to December 1969 in the data of the South Pole and Vostok high-altitude polar NMs on the Antarctic Plateau in search of possible sub-GLEs. We found two previously unknown events from 09 June 1968 and 27 February 1969 that formally match the definition of sub-GLE. They were associated with significant enhancements in the integral SEP intensity $J(>60\text{ MeV})$
J
(
>
60
MeV
)
measured by space-borne particle detectors, as well as with strong X-class solar flares from the western part of the solar disk. The identified sub-GLEs were analyzed and the corresponding SEP characteristics were estimated.
Effectiveness of Instant Messaging-Based Online Group Support for Preventing Smoking Relapse: a Pragmatic Randomized Controlled Trial
Authors: He Wan Jia Aaron , Wang Qi , Lam Tai Hing , Chan Ching Han Helen , Luk Tzu Tsun , Wang Man Ping , Chan Siu Chee Sophia , Cheung Yee Tak Derek 
Published: January 2024

AbstractOnline group support potentially help prevent smoking relapse. This two-arm, pragmatic, open-label randomized controlled trial assessed the effectiveness of instant messaging (IM) (i.e., WhatsApp) online group support versus text messages for smoking relapse prevention. The intervention group (n = 469) participated in 8-week counsellor-moderated IM-based online discussion groups and receive messages on preventing relapse via WhatsApp. The control group (n = 459) received similar messages via text messaging for 8 weeks. Primary outcome was biochemically validated tobacco abstinence (exhaled carbon monoxide < 4 parts per million; or saliva cotinine < 10 ng/ml) at 12-month follow-up. By intention-to-treat, intervention and control groups showed similar prevalence of biochemically validated abstinence (11.9% versus 11.7%, risk ratio [RR] = 1.01; 95%CI 0.71–1.44; P = 0.93). The interactive IM-based online group support was costly but did not increase smoking abstinence compared to simple text messaging. More interactive digital health interventions are more costly but may not be more effective than simple text messaging. ClinicalTrials.gov Identifier: # NCT03717051.