bluuebunny/crossref_metadata_2025_split huggingface dataset:
Informaciones contradictorias respecto a la compatibilidad con la lactancia materna de la vacuna frente al nuevo coronavirus
Authors: Pérez López Alba Isabel , Llinares Ramal Sandra , Segura Barrachina Sara , Bosch Marco María Teresa , Ferrándiz Mares Claudia , Jareño Roglán Enrique Jesús , Albert I Ros Xavier 
Published: January 2024

Introducción: Al inicio de la vacunación frente al SARS-CoV-2, se dieron una serie de informaciones contradictorias respecto a su compatibilidad con el embarazo y la lactancia (ficha técnica, medios de comunicación, sanitarios…) que pudieron generar dudas o decisiones inapropiadas a las madres lactantes con posibilidad de recibir la vacuna.
Objetivo: Analizar las decisiones que tomaron las madres respecto a la vacunación y la lactancia, y el origen de la información que pudo influir sobre esas decisiones.
Pacientes y métodos: Encuestas realizadas entre abril y mayo de 2021 a través de formularios on-line, a 280 madres que, mientras estaban amamantando, habían tenido opción de vacunarse frente a la COVID.
Resultados: En 45 casos se tomaron decisiones inapropiadas en función de informaciones contrarias o contradictorias sobre la compatibilidad de la vacuna con la lactancia: en 2 casos destetaron y 43 decidieron no vacunarse. 204 madres se vacunaron y siguieron amamantando, 66 pese a recibir informaciones contradictorias y 138 recibiendo la información apropiada. La información favorable a la compatibilidad se recibió principalmente a partir de fuentes especializadas en lactancia y la desfavorable a partir de los medios de comunicación (prensa, televisión, internet, etc.). Desde el ámbito sanitario se dieron el 52 % de las informaciones favorables y el 48 % de las desfavorables.
Conclusiones: Pese al rápido pronunciamiento de las sociedades científicas a favor de la vacunación en madres lactantes, durante los primeros meses se dieron con frecuencia informaciones contrarias o contradictorias al respecto, que pudieron condicionar decisiones inapropiadas como no vacunarse o destetar.
Networks Supporting Problem-Based Invention Education
Authors: SKUKAUSKAITE Audra , Saenz Cristina , Sullivan Michelle , Hull Katrina , Morales Rodriguez Jazmin 
Published: January 2024

Problem-based invention education engages students in complex processes of solving ill-defined problems with the support of teachers who act as facilitators of the learning process. Guided by interactional ethnographic epistemology (Green et al., 2012), we examine who and in what ways supported a high school team and their teacher working to invent a solution to a real-world problem students identified in their community. Our primary dataset included video recordings and a historian’s notebook collected by the InvenTeam historian during their invention project. Additional data included recordings of conversations with the teacher and the student historian who collaborated with university researchers in analyzing the InvenTeam year data. Through ethnographically informed domain and discourse analysis we identified three levels of the ecosystem that supported the team: local, national, and both. Analyses highlighted the role of technical mentors as a local support and the Lemelson-MIT program as a national support. Our study demonstrates the importance of the drawing on supports beyond the school to enable students and teachers to engage in problem-based invention education.
Problem-based Learning, a Tool to Develop Critical Thinking Skills of Undergraduate Veterinary Students
Authors: De Silva M. Lalanthi Wajiranjalee , Rabel R. A. Chanaka , Samita S. , Smith Nicola , McIntyre Lachlan , Parkinson Timothy J. , Wijayawardhane K. A. Nayana 
Published: January 2024

A major change embraced during a recent review of the Bachelor of Veterinary Science (BVSc.) curriculum of University of Peradeniya, Sri Lanka, was implementation of student-centred learning. Thus, a series of courses; ‘Integrated Veterinary Sciences’, delivered using Problem-based Learning (PBL), were introduced. As PBL is novel to the curriculum, this study was aimed to evaluate veterinary undergraduates’ perception on such a PBL-driven course which has been evaluated for the first time in Sri Lanka.
PBL sessions were conducted with volunteers of all four academic year groups. Responses were assessed, using a questionnaire, on the opportunity for improving critical thinking, discussions, facilitator guidance, e-learning and overall satisfaction of using PBL.
Over 85% of students across all groups agreed that the PBL had been effective: the highest level of agreement was on the potential to improve critical thinking. There were statistically significant differences between year groups for satisfaction with facilitators’ guidance and overall satisfaction; which may reflect differences in either content or facilitators’ experience between year groups.
PBL was well-received as a method for use in the veterinary curriculum, Sri Lanka, suggesting the possibility of its widespread use for vertical and horizontal integration. Teacher training and improving facilities would ensure the success.
Analysis of Potential Threats to the Critical Infrastructure of the 31st Tactical Air Base, in the Context of the Security of the Poznan Agglomeration
Authors: Geppert Karol , Konieczny Jerzy 
Published: January 2024

The main purpose of the article is an attempt to analyze the potential threats to the critical infrastructure of the 31st Tactical Air Base in Poznań-Krzesiny in terms of the security of the Poznań agglomeration. The main threats that may occur have been indicated in the context of military, non-military, asymmetric or hybrid activities. In addition, the mortgage effects of the actions taken, which can have a measurable impact on the safety of the Poznań agglomeration, were discussed and presented. An additional thread in the article is the indication of the existing threats that took place in the area of the Poznań-Krzesiny military airport, which could threaten the functioning of the critical infrastructure located in the area of the 31st Tactical Air Base and the critical infrastructure located in the area of the Poznań agglomeration.
The article does not contain any information or data defined as classified information in accordance with Ustawa z dnia 5 sierpnia 2010 r. o ochronie informacji niejawnych.
From Policy to Practice: Interpreting Polish Strategic Culture Amidst the Russian Full-Scale Invasion of Ukraine
Authors: Komarnytskyy Mykhaylo 
Published: January 2024

This research analyses the key components of the Polish strategic culture, mainly the national historical memory of previous relations with Russia, the role of NATO in Poland’s security and defence, the country’s objective to become a leading power in the Central and Eastern European, and the concept of strategic culture can become an additional explanatory determinant of Poland’s response to the Russian full-scale aggression against Ukraine. The case study considered Poland’s immediate firm and sweeping support of Ukraine in the first year of the Russian full-scale aggression.
This article aims to understand essential determinants in modern Polish foreign and security policy and how they played out during the Russian war against Ukraine. The paper applies the strategic culture as an example of the critical theoretical approach to explain how historically-based context and specific national identical features influence decision-making in present times. The study used a systemic review of related literature, media coverage of the latest Russian war against Ukraine developments, and deductive analysis methods.
The central assumption is that the concept of strategic culture becomes a crucial explanatory factor in understanding policy- and decision-making processes in the field of foreign and security policy. The main conclusions of the paper are that Poland’s response and reaction to Russia’s invasion of Ukraine is a continuation of the long-lasting policy maintained by Poland regarding the elimination of military and hybrid threats posed by Russia, reduction of Russian influence in Europe, development of the Eastern European region and strengthening relations with its staunch ally – the US.
Blood-based biomarkers in Alzheimer’s disease – moving towards a new era of diagnostics
Authors: Arslan Burak , Zetterberg Henrik , Ashton Nicholas J. 
Published: January 2024

Abstract
Alzheimer’s disease (AD), a primary cause of dementia globally, is traditionally diagnosed via cerebrospinal fluid (CSF) measures and positron emission tomography (PET). The invasiveness, cost, and limited accessibility of these methods have led to exploring blood-based biomarkers as a promising alternative for AD diagnosis and monitoring. Recent advancements in sensitive immunoassays have identified potential blood-based biomarkers, such as Aβ42/Aβ40 ratios and phosphorylated tau (p-tau) species. This paper briefly evaluates the clinical utility and reliability of these biomarkers across various AD stages, highlighting challenges like refining plasma Aβ42/Aβ40 assays and enhancing the precision of p-tau, particularly p-tau181, p-tau217, and p-tau231. The discussion also covers other plasma biomarkers like neurofilament light (NfL), glial fibrillary acidic protein (GFAP), and synaptic biomarkers, assessing their significance in AD diagnostics. The need for ongoing research and development of robust assays to match the performance of CSF and PET biomarkers is underscored. In summary, blood-based biomarkers are increasingly crucial in AD diagnosis, follow-up, prognostication, treatment response evaluation, and population screening, particularly in primary care settings. These developments are set to revolutionize AD diagnostics, offering earlier and more accessible detection and management options.
Coverage and reliability improvement of copper metallization layer in through hole at BGA area during load board manufacture
Authors: Zhu Kai , Xing Ruimin , Jiang Zhongming , Zhong Rongjun , Chen Liuming , Liu Jianhui , Miao Hua , Zhou Guoyun 
Published: January 2024

Abstract
The dimple of ball grid array (BGA) area with 70 mm × 70 mm size on load board for high performance integrated circuit final test is investigated by shadow moire at first, the dimple of BGA area decreases from 184.3 to 97.1 μm when six additional prepregs with 60 mm × 60 mm size are added at BGA area before hot lamination process. The micromorphology and stress/strain simulation are conducted to improve the coverage and reliability of copper metallization layer in through hole at that BGA area. The microcracks of electroless copper layer at the position of glass fiber and inner layer copper pad, which leads to serious crack after solder float, are well covered by subsequent electroplating copper layer. When the through holes at BGA area with 0.2 mm diameter and 7.0 mm depth are fabricated based on insulating dielectric material used for high-speed signal transmission, the simulation results point out that IT968 is better than M6G for the thermal shock reliability of through hole metallization layer. A load board vehicle with 126 layers and 8.3 mm thickness based on IT968 shows good interconnection structure reliability after 12 times 288°C solder float.
The grotesque as a literary issue
Authors: Ospanova Gulmariya , Askarova Altynai , Agabekova Balzhan , Zhutayeva Assel , Askarova Saule 
Published: January 2024

Abstract
Grotesque imagery is widely used by all genres and movements of art and literature without exception, but its historical development and theoretical aspects have not been sufficiently studied. This study seeks to define and diagnose the main aspects of the development of the grotesque as a literary problem. The leading methods of researching this problem are methods of analysis, deduction, induction, and comparison of approaches. The research covers the approaches to the study of the grotesque phenomenon; the interpretation of this trope is provided, its origin is described, in whose works it is widely used; the forms of grotesque and its specific features are described; various theoretical concepts of the question are demonstrated; the codes of grotesque poetics and their levels of display in the artistic system of works are identified; the qualities and features of Poe’s literary activity are diagnosed, and the components of the grotesque aesthetics are defined. The material in this study is of practical and theoretical value to students and literary scholars who study literature and its artistic features.
A multi-dimensional derivation model under the free-MERGE system: labor division between syntax and the C-I interface
Authors: Pan Victor Junnan , Du Yuqiao 
Published: January 2024

Abstract
This paper proposes a general multi-dimensional derivation model under a free-MERGE system. MERGE indicates the derivational dimensions that participate the computation. Set-MERGE is considered as an operation that keeps the two merge-mates in the same dimension, and Pair-MERGE sends the two merge-mates to two different dimensions. Each dimension has its own Labeling Algorithm (LA); the LA inside one dimension ignores syntactic objects merged from other dimensions. The resulting multi-dimensional structure will then be transferred to the Conceptual-Intentional (C-I) interface. A syntactic object resulted from Pair-MERGE will be interpreted in terms of coordination relation or modification relation. Different possible labelings in a multi-dimensional structure gives rise to different modification possibilities at C-I. C-I can see the competition of different labels, and will exhaust every possibility to decide which labeling gives rise to an appropriate interpretation.
Biomedical and agricultural applications of gold nanoparticles (AuNPs): a comprehensive review
Authors: Khan Sajad , Sher Khan Raham , Khalid Asaad , Gul Maria , Brekhna  , Wadood Abdul , Zahoor Muhammad , Ullah Riaz 
Published: January 2024

Abstract
The evolution of engineered nanoparticles (NPs); particularly metallic NPs have played an indispensable role in the development of nanotechnology. Among these NPs, gold nanoparticles (AuNPs) have attracted significant attention and are highly being utilized in several fields due to their exceptional properties. Gold nanoparticles were an emerging subject of intensive research due to their spherical shape, large specific surface area, and quick modification by functional groups. As the demand for AuNPs continuously increases; therefore, there is a pressing need to optimize the scientific approach to fully comprehend and exploit their potential. The effect of AuNPs on plant growth and development can either be beneficial or harmful, depending on the plant species and the concentration of NPs. Moderate concentrations of AuNPs have been found to induce primary and lateral roots, reduce oxidative stress, and elongate rosette diameter, while a higher concentration showed negative effects on plant growth and development. Gold nanoparticles also exhibit potent antibacterial, antiviral, and anticancer properties, making them most beneficial in various sectors, especially in the biomedical field. AuNPs are extensively being utilized across various sectors, but their application in the biomedical field is noteworthy, particularly in bioimaging, biosensing, targeted gene and drug delivery, theranostics, regenerative medicine, and tissue engineering. This review emphasizes the potential applications of AuNPs in diverse sectors including agriculture and biomedical, highlighting their potential impact (positive and negative) on plant growth. Furthermore, the review also aims to signify the mechanism of action of AuNPs and their efficacy against bacteria, viruses, and cancer cells.
Super-resolution ultrasound reveals cerebrovascular impairment in a mouse model of Alzheimer's Disease
Authors: Lowerison Matthew R. , Sekaran Nathiya Vaithiyalingam Chandra , Dong Zhijie , Chen Xi , You Qi , Llano Daniel A. , Song Pengfei 
Published: January 2024

Increasing evidence has suggested a link between cerebrovascular disease and the cognitive impairment associated with Alzheimer's Disease. However, detailed descriptions of microvascular changes across brain regions and how they relate to other more traditional pathology have been lacking. Additionally, the efforts to elucidate the interplay between cerebral microvascular function and Alzheimer's Disease progression are complicated by the necessity of probing deep-brain structures since early-stage Alzheimer's Disease typically involves hippocampal pathology. The purpose of this study was to examine changes in microvascular dynamics in a mouse model of Alzheimer's Disease using cohorts that were age-matched to wild-type controls. Data from both sexes were included in this study. Super-resolution ultrasound localization microscopy revealed microvascular functional and structural features throughout the whole brain depth to visualize and quantify. We found that functional decreases in hippocampal and entorhinal flow velocity preceded structural derangements in regional vascular density. Co-registered histological sectioning confirmed the regionalized perfusion deficits seen on ultrasound imaging, which were co-localized with amyloid beta plaque deposition. In addition to providing global vascular quantifications of deep brain structures with a high local resolution, this technology also permitted velocity-profile analysis of individual vessels and, in some cases, allowed for decoupling of arterial and venous flow contributions. These data suggest that microvascular pathology is an early and pervasive feature of Alzheimer's Disease and may represent a novel therapeutic target for this disease.Significance statementStudies of the impact of cerebrovascular pathology on Alzheimer's Disease are complicated by the difficulty of imaging deep-brain structures with high fidelity. We demonstrate that ultrasound localization microscopy, a super-resolution acoustic imaging technique, is capable of imaging cerebrovasculature throughout the entire depth of the mouse brain at a microvascular scale. This technology was applied to the 5xFAD mouse model of Alzheimer's Disease, where it was found that 5xFAD animals have significant impairments in vascular function in the entorhinal cortex and hippocampus compared to age matched controls at the 3-month timepoint. Structural derangements in cerebrovasculature were only observed at the 6-month-old timepoint, with a maintained impairment in vascular function. These findings suggest that microvascular pathology occurs early in the Alzheimer's Disease cascade.
Parametric design of cladding system for tall buildings using computational fluid dynamics approach
Authors: Colak Levent , Balci Mehmet Nurullah 
Published: January 2024

Quasi-static approach in calculation of wind load simply depends on the integration of the fluctuating pressures measured at pressure tubes located at the surface of building models. This approach is suitable to design typical low to medium height buildings. However, for tall buildings, if cladding surface will be designed based on single critical load in a conservative way, it will result in over design and excessive cost phenomena. The main aim of this study is to develop new experimantal and computational procedures to examine surface pressure distribution on tall buildings and to select cladding structure based on different pressure zones, thus in a more efficient way. A tall building is selected, modelled and 1/144 scaled wooden prototype is manufactured. Experimental study is conducted in a wind tunnel at turbulent flow conditions, and pressure values are recorded from tubes assembled on the surface of the prototype. Computational fluid dynamics (CFD) approach is carried out to determine pressure values and model is used in turbulent flow. Experimentally and computationally obtained results are observed compatible. After validation, actual wind profile is calculated, scaled and applied to the building model in simulations. Selection of the material thickness for the cladding system is performed parametrically accordint to deflection for elements in prescribed zones based on the computed pressure values. It is shown that new parametric cladding selection method opens up possibility to use less material consumption up to 23.6%, eliminating overdesign with maintaining desired factor of safety, which provides considerable economy on construction costs.
Exercise alleviates renal interstitial fibrosis by ameliorating the Sirt1-mediated TGF-β1/Smad3 pathway in T2DM mice
Authors: Chen Xianghe , Zeng Xinyu , Qiu Xiao , Liu Chi , Lu Pengcheng , Shen Ziming , Zhou Xiangxiang , Yang Kang 
Published: January 2024

Background
Renal interstitial fibrosis is the pathophysiological basis of type 2 diabetes mellitus (T2DM). Exercise appears to improve kidney interstitial fibrosis in T2DM, in which silent information regulator factor 2-related enzyme 1 (Sirt1) is a critical regulator. However, the role of Sirt1 in mediating exercise on renal tissue as well as its mechanism remains unknown.

Methods
T2DM mouse models were created using a high-fat diet mixed with streptozotocin, followed by 8 weeks of treadmill exercise and niacinamide (Sirt1 inhibitor) intervention. Kits for detecting biochemical indices of renal function were used. The pathological appearance and severity of renal tissue were examined using hematoxylin and eosin, Masson and immunohistochemical staining. The mRNA and protein expression of relevant signaling pathway factors were determined to use real-time reverse transcriptase-polymerase chain reaction and western blotting.

Results
T2DM can promote renal interstitial fibrosis, increase kidney index, serum creatinine, blood urea nitrogen and 24 h urinary total protein and cause pathological changes in renal tissue and affect renal function. After 8 weeks of exercise intervention, the biochemical indicators in the kidney of T2DM mice were decreased, Sirt1 expression was increased, the expression of TGF-β1, Smad3, collagen type I (COL1) and collagen type III (COL3) were decreased, and the renal interstitial fibrosis, renal tissue structural lesions and renal function were improved. However, after the nicotinamide intervention, renal interstitial fibrosis of T2DM mice was aggravated, and the improvement effect of exercise on renal interstitial fibrosis of T2DM mice was abolished.

Conclusion
The upregulation of Sirt1 expression by exercise can inhibit the transforming growth factor β1/Smad3 pathway, thereby inhibiting the expression and deposition of COL1 and COL3 in renal interstitium, thereby improving renal interstitial fibrosis in T2DM.
Effects of bovine ovarian storage conditions and vitrification on isolated preantral follicle viability
Authors: Franko Yasmin , de Almeida Monteiro Melo Ferraz Marcia 
Published: January 2024

Graphical abstract

Lay summary
The decreasing rate of successful pregnancies, both naturally and through assisted conception, has led to innovations in the way eggs, sperm, and embryos are stored. Despite these advances, the use of assisted reproductive techniques to preserve endangered or rare species remains unexplored. Since the location where samples are collected and facilities are often far apart, we aim to address part of this challenge by comparing different methods to store and handle ovarian tissue before freezing. This may pave the way for further research in preserving endangered species, despite the challenges posed by the distance between sample collection sites and suitable facilities.