bluuebunny/crossref_metadata_2025_split huggingface dataset:
Integrating Ugandan Fauna and Flora into Ceramic Art Identity
Authors: Kidega Samuel , Kwesiga Philip , Sizoomu George 
Published: November 2023

This study was carried out to exam the influence of integrating Ugandan fauna and flora into ceramic art identity, a multifaceted endeavor that encapsulates the essence of Uganda's rich biodiversity and cultural heritage within the realm of ceramic artistry. Through a fusion of artistic creativity and environmental conservation, this approach serves to foster a profound connection between artists, their heritage, and the natural world, presenting both aesthetic and socio-cultural benefits.
By exploring the fusion of Ugandan fauna and flora with ceramic art identity, the results emphasizes the potential for raising environmental awareness and advocating for the preservation of Uganda's unique ecosystems. Artists engaged in this innovative approach not only produce aesthetically striking works but also become advocates for the nation's diverse wildlife and plant life. Their creations serve as both mirrors reflecting the beauty of Uganda's natural world and lenses magnifying the importance of environmental stewardship.
Furthermore, the results highlighted the role of fauna and flora integration in preserving and expressing cultural identity. Indigenous communities in Uganda have historically maintained deep connections with their local environments, often rooted in the intricate relationship between culture and nature. By incorporating this cultural aspect into their ceramic art, Ugandan artists can kindle a renewed sense of appreciation for their cultural heritage and convey its significance to future generations.
In conclusion, the study sets the stage for a comprehensive exploration of integrating Ugandan fauna and flora into ceramic art identity. It underscores the potential for environmental and cultural enrichment through this fusion, offering a glimpse into the remarkable possibilities for artistic expression, cultural preservation, and ecological advocacy in Uganda's ceramic art scene.
Ramadan Fasting in Chronic Kidney Disease Patients: A Descriptive Observational Study
Authors: Megahed Abir Farouk , Abdel-Gawad Sara M. , El-Bahnasawy Nour Allah Magdy , Sayed-Ahmed Nagy 
Published: November 2023

Background: According to Islamic rules, a Muslim is requested to abstain from food, water, smoking, medications, and sexual activities from dawn until dusk, every day during the month of Ramadan. While Islam rules allow patients with appreciable illnesses not to fast, many Muslims, with chronic diseases, tend to stick to fasting, even against medical advice. However, there is no consensus among treating physicians regarding the fasting of Ramadan of patients in various stages of chronic kidney disease (CKD), especially those who insist on fasting regardless of their health problems.
Aim of the Work:We aimed to observe the practice of Ramadan fasting of CKD patients of different disease stages and its effect on CKD progression.
Methods and Subjects:The study observed sixty-three patients who were followed regularly at the Nephrology Outpatient Clinic in Mansoura Military Hospital, before, during, and after the month of Ramadan during summer in the years 2016-2019 to evaluate the effect of fasting on the patients and their kidneys. The study comprised two groups that comprised fifty fasting patients and thirteen in non -fasting group.
Results:The examined CKD patients included 47 males and 16 females who comprised 50 patients who practised fasting and 13 patients who did not fast the months of Ramadan according to their own will. Their ages ranged between 27 and 77 years. Forty-nine patients did not progress to end-stage renal disease (ESRD), while the remaining fourteen patients ended with dialysis during the study.Neither urea nor creatinine changes had statistically significant differences between patients who had and who had not fasted. In addition, differences in creatinine slope values between those who fasted did not show any statistical significance. Fourteen of the studied patients progressed to the need for dialysis; their mean age was 62 years. Of them, those who fasted included 3 patients of stage 4 and 6 patients of stage 5. Furthermore, the frequency of patients who started dialysis directly after Ramadan (six patients; 66.7%) were lower in the fasting group. Of the studied patients, seven had renal stones and opted to fast. All of them experienced occasional attacks of loin pain that increased during the first two weeks of fasting but decreased in the last two weeks of the month of Ramadan.
Conclusion: Compared to non-fasting, Ramadan fasting does not cause a significant extra risk of renal disease progression.
A VIOLÊNCIA DE GÊNERO E A LEI MARIA DA PENHA A PARTIR DE UMA PERSPECTIVA DECOLONIAL
Authors: Ferraz Gomes Naira Mariana , Motta Castro Amanda 
Published: November 2023

O objetivo do artigo é discorrer sobre a violência de gênero não como um fato social apartado, mas dentro do contexto de constituição da sociedade brasileira. O estudo baseia-se na lei n°11.340/2006 – Lei Maria da Penha. Pretende-se, a partir de uma perspectiva decolonial, mostrar a interseccionalidade da violência doméstica com outros marcadores sociais, especialmente os de raça e classe. A pesquisa é bibliográfica, balizada em leituras de artigos e obras relacionadas ao feminismo e violência de gênero., Por fim, pretende-se ressaltar que as políticas públicas de combate à violência doméstica devem estar engajadas na construção de uma sociedade com menos desigualdades sociais e emancipação coletiva das mulheres.
Evaluation of DermSat-7 for Assessing Treatment Satisfaction in Patients with Acne
Authors: Shields Ali , Armstrong April W. , Kaur Manraj N. , Layton Alison , Thiboutot Diane , Tan Jerry , Barbieri John S. 
Published: November 2023

ImportanceTreatment satisfaction is important to achieving therapeutic success in patients with inflammatory dermatological diseases, such as acne.ObjectiveTo evaluate the structural validity, internal consistency, and construct validity of the DermSat-7, a questionnaire-based measure of treatment satisfaction, in patients with acne seen in routine clinical practice.Design, Setting, and ParticipantsThis cross-sectional study included adults with acne who were fluent in English and treated at an outpatient clinic at Brigham and Women’s Hospital between July 2022 and May 2023. At each visit, patients completed a self-administered, patient-reported outcome questionnaire, including a patient global assessment (PGA) of their acne severity and the DermSat-7. The DermSat-7 consists of 7 items assessing 3 domains of treatment: effectiveness (3 items), convenience (3 items), and overall satisfaction (1 item). At subsequent visits, patients were asked an anchor item related to change in disease severity (“How has your acne changed compared to your last visit?”) that was scored on a 7-point scale (–3 = much worse to 3 = much better). Also at each visit, a dermatologist completed the Comprehensive Acne Severity Scale (CASS).Main Outcomes and MeasuresThe main outcomes were structural validity (assessed by factor analysis), internal consistency (assessed by Cronbach α), and construct validity (assessed using linear regression models and Pearson correlation coefficients).ResultsThe analysis included 142 patients with acne (mean [SD] age, 25.1 [5.1] years; 96 females [67.6%]) taking acne medication who completed the DermSat-7. Exploratory factor and confirmatory factor analysis supported the unidimensionality of the 3 DermSat-7 domains. Cronbach α values of 0.89 and 0.80 supported good internal consistency in the effectiveness and convenience domains, respectively. Known-groups validity was supported by increasing DermSat-7 effectiveness and overall satisfaction scores with increasing levels of positive change in disease severity (linear regression coefficient, 7.51; 95% CI, 4.94-10.08; P &amp;lt; .001). Construct validity was further supported by moderate correlations with the anchor, PGA, and CASS scores (effectiveness domain: anchor r = 0.567, PGA r = –0.538, and CASS r = –0.485; overall satisfaction domain: anchor r = 0.467, PGA r = –0.486, and CASS r = –0.489).Conclusion and RelevanceThis cross-sectional study found that the DermSat-7 may be an effective tool for measuring treatment satisfaction, particularly effectiveness and overall satisfaction domains, among patients with acne. Further research is needed to examine additional measurement properties of the DermSat-7, such as content validity and interpretability, as well as to validate the DermSat-7 in other populations of patients with acne.
Outcomes of the 340B Drug Pricing Program
Authors: Knox Ryan P. , Wang Junyi , Feldman William B. , Kesselheim Aaron S. , Sarpatwari Ameet 
Published: November 2023

ImportanceThe 340B Drug Pricing Program requires manufacturers to offer discounted drug prices to support safety net hospitals and clinics (covered entities) providing care to low-income populations. Amid expansion, the program has received criticism and calls for reform.ObjectiveTo assess the literature on the foundations of and outcomes associated with the 340B program.Evidence ReviewThe databases searched in this scoping review included PubMed, Embase, EconLit, National Bureau of Economic Research (NBER), Westlaw, the Department of Health and Human Services Office of the Inspector General (HHS-OIG) website, the Government Accountability Office (GAO) website, and Google in February 2023 for peer-reviewed literature, legal publications, opinion pieces, and government agency and committee reports related to the 340B program.FindingsAmong a collected 900 documents, 289 met inclusion criteria: 83 articles from PubMed, 12 articles from Embase, 2 articles from EconLit, 1 article from NBER, 28 articles from Westlaw, 23 legislative history documents, 103 documents from Google, 11 GAO reports, and 26 HHS-OIG reports. Included literature pertained to 4 stakeholders in the 340B program: covered entities, pharmacies, pharmaceutical manufacturers, and patients. This literature showed that hospitals, clinics, and pharmacies generated revenue and manufacturers have forgone revenue from 340B discounted drugs. Audits of covered entities found low rates of compliance with 340B program requirements, whereas mixed evidence was uncovered on how covered entities used their 340B revenue, with some studies suggesting use to expand health care services for low-income populations and others to acquire physician practices and open sites in higher-income neighborhoods. These studies were hampered by a lack of transparency and reporting on the use of 340B revenue. Studies revealed patient benefits from access to expanded health care services, but there was mixed evidence on patient cost savings. Although the review identified considerable research on 340B hospitals, pharmacies, and patients, less research was found evaluating the 340B program’s effect on nonhospital covered entities, drug pricing, and racial and ethnic minority groups.Conclusions and RelevanceIn this scoping review of the 340B program, we found that the 340B program was associated with financial benefits for hospitals, clinics, and pharmacies; improved access to health care services for patients; and substantial costs to manufacturers. Increased transparency regarding the use of 340B program revenue and strengthened rulemaking and enforcement authority for the Health Resources and Services Administration would support compliance and help ensure the 340B program achieves its intended purposes.
How is preschoolers' memory performance related to parental elaboration during reminiscence?
Authors: Léonard Christina , Geurten Marie , Willems Sylvie 
Published: November 2023

AbstractThe influence of parental reminiscing style – how parents discuss past events with their child – on preschoolers' independent memory skills (outside of parent–child conversations) and the processes involved in this effect (memory consolidation vs. development of strategies) is far from clear. To test this, 50 parent–child dyads (MChildAge = 52.12) were recruited. Parents' level of elaboration during reminiscing was measured while children completed tasks assessing their memories about two standardized events, one they had discussed with their parent and one they had not discussed, and an episodic task requiring the memorization of new information. Children of high‐elaborative parents performed better than children of low‐elaborative parents on the recognition test for the non‐discussed event and for the episodic memory task. This suggests that parental elaboration is related to preschoolers' independent memory skills and that its effect might exceed memory consolidation and depend on processes like the acquisition of strategies.
Liver‐Derived Ketogenesis via Overexpressing HMGCS2 Promotes the Recovery of Spinal Cord Injury
Authors: Sun Xiaofei , Zhang Bin , Sun Kaiqiang , Li Fudong , Hu Dongping , Chen Juxiang , Kong Fanqi , Xie Yang 
Published: November 2023

AbstractThe liver is the major ketogenic organ of the body, and ketones are reported to possess favorable neuroprotective effects. This study aims to elucidate whether ketone bodies generated from the liver play a critical role in bridging the liver and spinal cord. Mice model with a contusive spinal cord injury (SCI) surgery is established, and SCI induces significant histological changes in mice liver. mRNA‐seq of liver tissue shows the temporal changes of ketone bodies‐related genes, β‐hydroxybutyrate dehydrogenase (BDH1) and solute carrier family 16 (monocarboxylic acid transporters), member 6 (SLC16A6). Then, an activated ketogenesis model is created with adult C57BL/6 mice receiving the tail intravenous injection of GPAAV8‐TBG‐Mouse‐Hmgcs2‐CMV‐ mCherry ‐WPRE (HMGCS2liver) and mice receiving equal AAV8‐Null being the control group (Vectorliver). Then, the mice undergo either a contusive SCI or sham surgery. The results show that overexpression of HMG‐CoA synthase (Hmgcs2) in mice liver dramatically alleviates SCI‐mediated pathological changes and promotes ketogenesis in the liver. Amazingly, liver‐derived ketogenesis evidently alleviates neuron apoptosis and inflammatory microglia activation and improves the recovery of motor function of SCI mice. In conclusion, a liver‐spinal cord axis can be bridged via ketone bodies, and enhancing the production of the ketone body within the liver has neuroprotective effects on traumatic SCI.
Organic–Inorganic Copper Halide Compound with a Near‐Unity Emission: Large‐Scale Synthesis and Diverse Light‐Emitting Applications
Authors: Chen Kunlin , Chen Bingkun , Xie Lingling , Li Xitao , Chen Xiyao , Lv Ning , Zheng Kun , Liu Zhe , Pi Huihui , Lin Zhengguo , Rogach Andrey L. 
Published: November 2023

AbstractLow‐dimensional organic–inorganic metal halides (OIMHs) have emerged as promising light emitters due to their broadband emission originating from self‐trapped excitons (STE), especially for Cu‐based OIMHs. Herein, Cu(I)‐based OIMH with a structure of (TPP)2Cu4I6·2DMSO (TPP stays for tetraphenylphosphonium, and DMSO – for dimethyl sulfoxide) has been synthesized, both in form of single crystals and as a microcrystalline powder. This compound exhibits a broadband green emission with a peak at 515 nm and a full width at half‐maximum of 78 nm, and a near‐unity photoluminescence quantum yield of 99.5%. Experimental data supported by theoretical calculations indicate that the STE emission is responsible for the green emission with a long lifetime of 2.53 µs. Down‐conversion light‐emitting device with a high luminous efficiency of 50 lm W−1 based on this compound have been fabricated, and white light has also been achieved with a high color rendering index of 96.7. Moreover, green emissive (TPP)2Cu4I6·2DMSO is utilized in scintillators for X‐ray detection and imaging, and as a luminescent ink for encryption applications.
Entropy Engineering on 2D Metal Phosphorus Trichalcogenides for Surface‐Enhanced Raman Scattering
Authors: Wang Ran , Chen Mengxin , Han Jiecai , Zhang Xinghong , Zhang Zhihua , Yao Tai , Wang Yi , Xu Lingling , Wang Xianjie , Xu Ping , Song Bo 
Published: November 2023

AbstractSurface‐enhanced Raman scattering (SERS) spectroscopy is an ultrasensitive detection technique for molecular identification in both biology and chemistry. 2D materials have displayed increasing potentials as SERS substrates based on chemical enhancement, where optimization of the band structure to promote the charge transfer is exceptionally important. Here, the regulation of band structure of 2D metal phosphorus trichalcogenides (MPCh3) via entropy engineering is demonstrated. The optimized high‐entropy MnFeCuAgInPS3 nanosheets (NSs) with narrowed bandgap (Eg) show significant SERS performance with a low detection limit with 10−9 m for both rhodamine 6G and crystal violet. Combined spectral characterizations and density functional theory (DFT) calculations reveal that the combination of multiple hetero‐element provides continuous d orbitals and endows high‐entropy MPCh3 NSs with high population of electrons at the energies near Fermi level (EF), which allows highly efficient photo‐induced charge transfer (PICT) between the SERS substrates and target molecules. This work affords a new strategy for high‐performance 2D SERS materials and also reveals the origin of the band structure regulation by entropy engineering.
Intramolecular Donor–Acceptor Design in Porous Organic Framework for Liquid Fuels Adsorption Desulfurization
Authors: Wang Shanshan , Li Yinhui , Fu Yu , Li Xiaoyu , Tao Chunhui , Zhang Wenxiang , Ma Heping 
Published: November 2023

AbstractA porous organic framework containing well‐defined donor–acceptor units, named donor–acceptor porous organic framework (D–A‐POF), is successfully synthesized. The localized electric field gradient at the pore surface induced by the intramolecular donor–acceptor (D–A) interactions endows D–A‐POF with excellent desulfurization capabilities. D–A‐POF exhibits high adsorption capacity of 3‐methylthiophene (12.26 mmol g−1, 392.32 mg S g−1) and 1‐benzothiophene (793.65 mg g−1, 189.25 mg S g−1) with impressive adsorption selectivity. Density functional theory calculations provide compelling evidence of the preferential selective adsorption of aromatic thiophene sulfides in D–A‐POF. In fixed‐bed breakthrough experiments, D–A‐POF demonstrates its ability to selectively capture thiophene sulfides from model gasoline, resulting in fuel with sulfide content below 10 ppb. The high stability and high desulfurization efficiency of D–A‐POF make it promising as a new porous adsorbent for ultra‐depth adsorption desulfurization.
Cellular Architects at Work: Cells Building their Own Microgel Houses
Authors: Bulut Selin , Günther Daniel , Bund Michelle , Haats Christina , Bissing Thomas , Bastard Céline , Wessling Matthias , De Laporte Laura , Pich Andrij 
Published: November 2023

AbstractMicroporous annealed particle (MAP) scaffolds are investigated for their application as injectable 3D constructs in the field of regenerative medicine and tissue repair. While available MAP scaffolds provide a stable interlinked matrix of microgels for cell culture, the infiltration depth and space for cells to grow inside the scaffolds is pre‐determined by the void fraction during the assembly. In the case of MAP scaffolds fabricated from interlinked spherical microgels, a cellularity gradient can be observed with the highest cell density on the scaffold surface. Additionally, the interlinked microgel network limits the ability of cells to remodel their environment, which contradicts native tissue dynamics. In this work, a cell‐induced interlinking method for MAP scaffold formation is established, which avoids the necessity of chemical crosslinkers and pre‐engineered pores to achieve micro‐ or macropores in these 3D frameworks. This method enables cells to self‐organize with microgels into dynamic tissue constructs, which can be further controlled by altering the microgel properties, the cell/microgel ratio, and well shape. To form a cell‐induced interlinked scaffold, the cells are mixed with dextran‐based microgels and function as a glue between the microgels, resulting in a more homogenous cell distribution throughout the scaffold with efficient cell–cell interactions.
Synergistic Pharmacological Therapy to Modulate Glial Cells in Spinal Cord Injury
Authors: Veneruso Valeria , Petillo Emilia , Pizzetti Fabio , Orro Alessandro , Comolli Davide , De Paola Massimiliano , Verrillo Antonietta , Baggiolini Arianna , Votano Simona , Castiglione Franca , Sponchioni Mattia , Forloni Gianluigi , Rossi Filippo , Veglianese Pietro 
Published: November 2023

AbstractCurrent treatments for modulating the glial‐mediated inflammatory response after spinal cord injury (SCI) have limited ability to improve recovery. This is quite likely due to the lack of a selective therapeutic approach acting on microgliosis and astrocytosis, the glia components most involved after trauma, while maximizing efficacy and minimizing side effects. A new nanogel that can selectively release active compounds in microglial cells and astrocytes is developed and characterized. The degree of selectivity and subcellular distribution of the nanogel is evaluated by applying an innovative super‐resolution microscopy technique, expansion microscopy. Two different administration schemes are then tested in a SCI mouse model: in an early phase, the nanogel loaded with Rolipram, an anti‐inflammatory drug, achieves significant improvement in the animal's motor performance due to the increased recruitment of microglia and macrophages that are able to localize the lesion. Treatment in the late phase, however, gives opposite results, with worse motor recovery because of the widespread degeneration. These findings demonstrate that the nanovector can be selective and functional in the treatment of the glial component in different phases of SCI. They also open a new therapeutic scenario for tackling glia‐mediated inflammation after neurodegenerative events in the central nervous system.
Thick Does the Trick: Genesis of Ferroelectricity in 2D GeTe‐Rich (GeTe)m(Sb2Te3)n Lamellae
Authors: Cecchi Stefano , Momand Jamo , Dragoni Daniele , Abou El Kheir Omar , Fagiani Federico , Kriegner Dominik , Rinaldi Christian , Arciprete Fabrizio , Holý Vaclav , Kooi Bart J. , Bernasconi Marco , Calarco Raffaella 
Published: November 2023

AbstractThe possibility to engineer (GeTe)m(Sb2Te3)n phase‐change materials to co‐host ferroelectricity is extremely attractive. The combination of these functionalities holds great technological impact, potentially enabling the design of novel multifunctional devices. Here an experimental and theoretical study of epitaxial (GeTe)m(Sb2Te3)n with GeTe‐rich composition is presented. These layered films feature a tunable distribution of (GeTe)m(Sb2Te3)1 blocks of different sizes. Breakthrough evidence of ferroelectric displacement in thick (GeTe)m(Sb2Te3)1 lamellae is provided. The density functional theory calculations suggest the formation of a tilted (GeTe)m slab sandwiched in GeTe‐rich blocks. That is, the net ferroelectric polarization is confined almost in‐plane, representing an unprecedented case between 2D and bulk ferroelectric materials. The ferroelectric behavior is confirmed by piezoresponse force microscopy and electroresistive measurements. The resilience of the quasi van der Waals character of the films, regardless of their composition, is also demonstrated. Hence, the material developed hereby gathers in a unique 2D platform the phase‐change and ferroelectric switching properties, paving the way for the conception of innovative device architectures.