bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of monocyte to high-density lipoprotein cholesterol ratio and other inflammatory markers in hidradenitis suppurativa: a case-control study
Authors: UTLU Zeynep , ÖZBEK ŞEBİN Saime , METİN Nurcan 
Published: December 2023

Aims: Hidradenitis suppurativa (HS) is an inflammatory disease whose pathophysiology is not yet clearly known, but inflammatory parameters have been used for many years in the diagnosis and follow-up. The aim of this study is to evaluate NLR, PLR, MHR, and hemogram parameters in patients diagnosed with HS without comorbidities and compare them with healthy controls.
Methods: This study include 105 HS patients and 100 healthy volunteers. The medical records and laboratory findings of the participants were reviewed retrospectively. Patients and control group neutrophils, lymphocytes, monocytes, platelets, mean platelet volume (MPV), platelet distribution width (PDW), red cell distribution width coefficient of variation (RDW-CV), high-density lipoprotein cholesterol (HDL-C), C-reactive protein (CRP), Neutrophil-lymphocyte ratio (NLR), monocyte-lymphocyte ratio (MLR), platelet-lymphocyte ratio (PLR), and MHR were compared.
Results: A total of 105 patients [43 (41%) women and 62 (59%) men] and one hundred healthy volunteers [52 (52%) women and 48 (48%) men] participated in the study. The mean of neutrophil count (patient group=5.84±2.27, control group=4.29±1.81, p=0.001), lymphocyte count (patient group=2.78±0.90, control group=2.31±0.63, p=0.001), monocyte count (patient group=0.74±0.39, control group=0.55±0.16, p=0.001), platelet count (patient group=295.63±65.84, control group=274.45±59.06, p=0.007), CRP (patient group=12.71±24.38, control group=2.61±2.21, p=0.039), and MHR (patient group=0.0203±0.0135, control group=0.0114±0.0056, p=0.001) were higher in the patient whereas the mean of HDL-C (patient group=39.02±11.06, control group=52.85±16.46, p=0.001) and PLR (patient group=118.82±60.82, control group=126.07±39.13, p=0.028) were significantly higher in control individuals. The adjusted effect of MHR, NLR, and PLR was re-examined to eliminate the effect that may arise from the difference in age between patients and controls. It was observed that when MHR increased by 0.01 unit, the risk of disease increased significantly by 4.07 times. When NLR increases by 1 unit, the disease increased. significantly by 1.37 times. Both adjusted and unadjusted effects of MHR were significant. When the sensitivity and specificity of MHR, and NLR in differentiating patients were examined, the sensitivity of MHR was found to be 67.4% and its specificity was 72.5% (p=0.001), while the sensitivity of NLR was found to be 61.5% and its specificity was 74.0% ( p=0.038).
Conclusions: Our study showed that MHR was more effective in distinguishing HS patients than other inflammatory markers. MHR can be used as a new marker to investigate the inflammatory effect of HS.
Employment status, presence of chronic disease and daily screen time are determinants of healthy diet literacy
Authors: YILMAZ Birsen 
Published: December 2023

Aims: While it has become easier for consumers to reach information with the developments in technology, however, to be able to find the right resources for the information has become difficult. It is known that this situation is related to the health and nutrition literacy of individuals. In this study, it was aimed to determine health literacy, digital healthy diet literacy and healthy eating attitudes of adult individuals.
Methods: Study data were collected with the help of a questionnaire form from 150 individuals (106 females and 44 males, mean age 32.1±10.62 years) who live in Türkiye and voluntarily agreed to participate in the study between January and June 2023.
Results: More than half of the participants (56%) were found to have more than six hours of daily screen time. The most common sources of information on health and nutrition are reported as academic databases and Instagram (both 30.7%). In both genders, individuals' eating attitudes towards healthy eating were found to be high. When the factors affecting health literacy and digital healthy diet literacy were examined, it was seen that daily screen time, working status and having chronic diseases were statistically important factors (p
Colonoscopy indications and findings in older adults
Authors: BAKKALOĞLU Oğuz Kağan , ESKAZAN Tuğçe , CANDAN Selçuk , ERZİN Yusuf , DOBRUCALI Ahmet Merih 
Published: December 2023

Aims: The share of older population is increasing globally. Colonoscopy is a frequently used diagnostic/therapeutic procedure, no study to our knowledge comprehensively examines the indications and findings of colonoscopy in geriatric population. We aimed to reveal these in older adults.
Methods: Colonoscopy procedures performed in older adults (≥65 years), which covered a 5-year period (2017-2022), were analyzed retrospectively. Indications and findings of colonoscopies were assessed. The relationship between the indications and the associated findings was also evaluated on an indication basis.
Results: In the study, 2370 colonoscopy procedures were examined. 27.8% were performed in very old (≥75 years) patients. Colonoscopy was completed in 84.3%. Colon cleansing was not optimal in approximately one-fourth. The frequency of completion of colonoscopies and optimal cleaning were similar in the very old. Iron deficiency anemia (IDA) or fecal occult blood test (FOBT) positivity and screening colonoscopy were the common indications. Regarding indications, IDA-FOBT positivity and bleeding were more frequent, screening colonoscopy, IBD and polyp control were less frequent in the very old group. Colonoscopy was reported as normal in 42.4% of the patients, while polyps (28.3%) and diverticula (17.5%) were the common findings. Among findings tumor, diverticula and solitary rectal ulcer were higher in the very old. IDA -FOBT positivity, bleeding, and colonoscopy performed due to findings of other imaging modalities were related to diagnosis of a tumor.
Conclusion: In this study, we presented the indications and results of colonoscopy in a large number of older patients. The main indications for colonoscopy can be listed as IDA-FOBT positivity, screening colonoscopy and control of previous polyp-tumor. Near one of two colonoscopies were found to be normal, polyps and diverticula were the major pathologies in the rest. It should be emphasized that IDA -FOBT positivity, bleeding, and findings of other imaging modalities were related to tumor in colonoscopy.
Evaluation of one-point fixation surgery with computer-aided root mean square deviation in zygomaticomaxillary complex fractures
Authors: OKYAY Mehmet Fatih 
Published: December 2023

Aims: Our paper aimed to present the results of the one-point fixation method in zygomaticomaxillary fractures by computer-aided mirror image superimposition with root mean square (RMS) deviation.
Methods: One-point fixation performed zygomaticomaxillary complex fracture patients (n=18) by one surgeon were included in our study. Virtual 3D data of preoperative and postoperative CT-scan images was obtained by Slicer software. Sagittal plan mirror image superpositioning were used to obtain RMS data by Slicer. Mirror image superimposition of the undamaged side to the broken side in preoperative CT-scan imaging was referred as group B or broken group. Superposition of the repaired side’s postoperative imaging to the preoperative broken side was measured as group R or repair group in order to examine zygomatic bone’s postoperative spatial location. Superpositioned mirror 3D images of the non-traumatic side onto post-fixation 3D in postoperative data was measured as group M or mirror group. RMS deviation values of the groups obtained by Slicer were statistically compared.
Results: Shapiro-Wilk test of groups were demonstrated normal distribution of the data for each group with no difference (p>0.05). In order to compare between groups, paired t-test covariance analysis were shown statistically similar data distrubition between experimental groups (p>0.05).
Conclusion: Considering the nature of maxillofacial surgery, which disapproves even millimetric errors, we believe that the mean square root deviation will become standard as it allows three-dimensional evaluation and precise mathematical measurements. Besides, in accordance with the recent literature, this study might pay the way for future studies that would increase the usage of the one-point fixation method conducted on larger case series, as this method prevents lower eyelid complications without a visible scar.
Real-life data of azacitidine-venetoclax combination in acute myeloid leukemia patients: a single center experience
Authors: BULDUK Tuba , CÖMERT Melda , KILIÇ Ebru , SAYIN Selim , YILDIRIM Murat , AYLI Meltem 
Published: December 2023

Aims: To evaluate real-life data on the efficacy and safety of Venetoclax (Ven) therapy used in combination with hypomethylating agent (HMA) in patients with acute myeloid leukemia (AML).
Methods: The records of newly diagnosed, relapsed or refractory (RR) AML patients over 18 years of age who were planned to be treated with Azacitidine (AZA) combined with Ven because they were not suitable for intensive chemotherapy and patients who received AZA combined with Ven maintenance therapy after achieving remission were retrospectively analyzed. The standard protocol for patients is subcutaneous or intravenous AZA 75 mg/m2 on days 1-7/ every 28 days + oral Ven treatment 100-400 mg/day for 28 days. The treatment response rates, survival times, and side effect profiles of 18 newly diagnosed patients, 12 RR patients, and 4 patients receiving AZA+Ven as maintenance treatment between January 2021 and March 2022 were evaluated.
Results: It was found that 8 of the 34 patients (23.5%) who were examined in the present study died before the first response could be evaluated. When the response rates were evaluated, complete response (CR) or complete remission with incomplete blood count recovery (CRi) (CR+CRi) was found to be 61% in the group receiving AZA+Ven in the first line, and CR+CRi was 50% in the group receiving AZA+Ven because of RR AML. In the group receiving AZA+Ven in the first line, the average Overall Survival (OS) was 8.00 months (95% CI: 1.58-14.41), and 7.00 months in the RR group (95% CI: 1.78-12, 21). All patients in the group receiving AZA+Ven for maintenance purposes were alive and the median follow-up period was 12.50±6.02 months in this group (Mean±SD). The most common side effect was neutropenia, and the most common cause of death was disease progression.
Conclusion: In AML patients ineligible for intensive treatment due to advanced age or comorbidities, real-life data of AZA+Ven therapy with effective CR+CRi rates and a manageable spectrum of side effects promise hope.
Does nutrition knowledge level affect food group preferences and obesity in individuals aged 19 years and older?
Authors: ÇAKIR Biriz , NİŞANCI KILINÇ Fatma , EKİCİ Emine Merve , ÖZENİR Çiler 
Published: December 2023

Aims: This study was conducted to determine the relationship between nutrition knowledge level, food group preferences, and obesity in individuals who applied to family health centers.
Methods: This study is a cross-sectional study and was conducted with individuals aged 19 years and over. The nutrition knowledge level of the individuals was determined with the nutrition knowledge test, anthropometric measurements were taken, and nutrition status was evaluated with a food frequency questionnaire and 24 hour-recall food consumption records. The data obtained from the study were analyzed with the SPSS 21.0
Results: Of the 1797 individuals who participated in the study, 70.5% were female, 22.0% were single, and 22.8% were university graduates. The mean nutrition knowledge score (NKS) was higher in singles (43.39±13.93) (p=0.001), university graduates (46.05±13.69) (p
The mediating role of emotional eating in the relationship between aggression and eating attitudes
Authors: TÜRKMEN Gözde , BAYRAM KUZGUN Tubanur 
Published: December 2023

Aims: Negative emotions and thoughts are known to be associated with eating problems. In recent years, strong relationships have been established between disordered eating attitudes and aggression, which are important in the growth of increasing eating disorders. This article examines the mediatory role of emotional eating in the relationship between aggression and disordered eating attitudes in adult individuals.
Methods: The study included 293 participants, including 70 males and 223 females, accessed through a convenience sampling method. In the study, participants completed the Demographic Information Form, the Eating Attitude Test, the Buss-Perry Aggression Scale, and the Turkish Emotional Eating Scale.
Results: Participants with disordered eating attitudes and emotional eating were found to have significantly higher average aggression scores than participants with healthy eating attitudes and without emotional eating. There has been a positive significant relationship between hostility and emotional eating and between hostility and disordered eating attitudes. The results of the structural equation model showed that among the types of aggression, only hostility and all disordered eating attitudes (preoccupation with eating, restriction, social pressure) played an instrumental role in the relationship.
Conclusion: Hostility and emotional eating behavior should be addressed in different preventive studies and intervention programs in which disordered eating attitudes seem in the fields of both mental health and health sciences.
The evaluation of tear production and dry eye symptoms in patients with osteoporosis
Authors: BENLİ KÜÇÜK Esin , KÜÇÜK Erkut 
Published: December 2023

Aims: Osteoporosis is a systemic skeletal disorder characterized by decreased bone mass, compromised bone density and strength. Dry eye is a common disease of the ocular surface characterized by tear film instability with ocular discomfort, pain, and visual disturbances. Both conditions share risk factors, including age, gender, and hormonal factors. In this study, our aim is to assess the tear production and dry eye symptoms in patients with osteoporosis and compare their results a control group without osteoporosis.
Methods: In this cross-sectional study, we evaluated 32 osteoporosis patients and 30 age-matched controls without osteoporosis. Tear production was assessed using Schirmer test and the symptoms of dry eye using Ocular Surface Disease Index (OSDI) questionnaire. The results of both groups were compared.
Results: The mean age of the osteoporosis group was 61.4±4.9 years, and the mean age of the control group was 57.7±6.4 years (p:0.224). The Schirmer test results were 12.3±7.4 mm for the osteoporosis group and 23.1±13.7 mm for the control group. The Schirmer test results were significantly lower in the osteoporosis group (p:0.009). The mean OSDI scores for the osteoporosis group was 30.4±23.1 while it was 20.6±14.6 for the control group. The difference was not statistically significant (p:0.329).
Conclusion: This study reveals a potential connection between osteoporosis and dry eye. Patients with osteoporosis have lower tear production compared to control group without osteoporosis. Further research is necessary to understand this relationship and its implications.
Utilizing the MRI findings to diagnose acute appendicitis in pregnant women
Authors: YILDIZ Zeynep , MUTLU Fuldem 
Published: December 2023

Aims: To assess the performance of magnetic resonance ımaging (MRI ) scale for the diagnosis of acute appendicitis in pregnant women and to determine the added diagnostic value of MRI imaging.
Methods: In this retrospective study, the data of patients who presented to our hospital emergency department between January 2018 and December 2021, had clinical and laboratory findings consistent with acute appendicitis, and were diagnosed with radiological imaging, were extracted from the hospital automation system and used for statistical analysis. Ultrasound (US) was used as the first-line diagnostic method for pregnant patients, and magnetic resonance imaging (MRI) was used as the second-line diagnostic method. The success of US and MRI examinations in diagnosing acute appendicitis was evaluated. In MRI examinations, the mean values of appendix diameter and wall thickness parameters were examined, and the sensitivity, specificity, positive predictive value, and negative predictive value of periappendiceal fat tissue intensity increase, T2A lumen hyperintensity, and periappendiceal fluid parameters were evaluated. Additionally, the frequency of acute appendicitis according to trimesters was examined. SPSS v20.0 (IBM SPSS Statistics for Windows, Version 20.0; Armonk, NY, USA) package program was used for the analysis.
Results: When the medical records of 200 patients diagnosed with appandicitis were retrospectively examined, it was determined that there were 13 pregnant cases diagnosed with MRI during this period. Sensitivity, specificity, positive predictive value, and negative predictive value were evaluated for parameters including intraluminal T2A hyperintensity, wall thickness, periappendiceal fluid accumulation, and periappendiceal fatty tissue intensity increase. İntraluminal T2A hyperintensity and also periappendiceal fatty tissue intensity increase parameter sensitivity was 100%, however the wall thickness parameter had a sensitivity of 60% and the periappendiceal fluid accumulation parameter had a sensitivity of 80%. the periappendiceal fatty tissue intensity increase parameter had a a specificity of 33.3%, which is the lowest ratio among the other parameters. there was also no significant difference in the frequency of acute appendicitis according to trimesters
Conclusion: MRI examination has a high success rate and can be used as the primary diagnostic method for pregnant appandicitis cases. In terms of parameter evaluation, the highest positive predictive value (90.9%) is found by the parameter of intraluminal T2 hyperintensity, and the parameter of periappendiceal fluid collection is found to be in the second place. The success of T2A lumen hyperintensity and periappendiceal fat tissue intensity increase parameters, especially in excluding negative cases, was found to be quite high.
The effect of 18F-FDG PET/CT findings on prognosis in patients with diffuse large B cell lymphoma
Authors: YILMAZ Seda , EROL Mustafa 
Published: December 2023

Aims: 18F-fluorodeoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT), plays an important role in both staging at the time of diagnosis and follow-up of treatment response in lymphoma. Our aim was to investigate the effect of different quantitative metabolic parameters, which are not used in routine practice, on treatment response and overall survival (OS) in patients with diffuse large B-cell lymphoma.
Methods: A total of 26 patients were included in our retrospective cohort study. Deauville 5-point scale (5-PS), and cut-off values for changes in maximum standardized uptake value (SUVmax), peak SUV (SUVpeak), metabolic tumor volume (MTV)(2.5-%41- PERCIST -aort) and total lesion glycolysis index (TLG) (2.5-%41- PERCIST-aort) effect of metabolic parameters on treatment response and OS was investigated.
Results: Metabolic parameters did not predict treatment response, while TLGPERCIST (p=0.034), TLGAORT (p=0.040), MTV41 (p=0.040) and TLG41 (p=0.034) parameters were statistically significant for OS. Median OS (months) was statistically significant in TLGPERCIST groups (p=0.047). While the median OS (months) in the TLGPERCIST
PENGARUH SUBSTITUSI ABU AMPAS TEBU SEBAGAI FILLER TERHADAP KUALITAS CAMPURAN ASPHALT CONCRETE-BINDER COURSE (AC-BC) BERDASARKAN UJI MARSHALL
Authors: Gutama Detha Sekar Langit Wahyu , Sulistyorini Dewi , Pamulatsih Wening Ratri , Handayani Elisa Fitri 
Published: December 2023

<em>Jalan merupakan prasarana yang sangat penting dalam sistem transportasi darat guna mendukung semua aktifitas sehari-hari. Meningkatnya pertumbuhan volume lalu lintas akan berdampak terhadap permintaan pembangunan struktur perkerasan jalan yang salah satunya berupa perkerasan lentur. Bahan pembuatan perkerasan lentur terdiri dari aspal, filler dan agregat. Perencanaan campuran aspal perlu pertimbangan khusus diantaranya kompisisi campuran agregat kasar, agregat halus maupun filler. Penelitian ini menggunakan abu ampas tebu sebagai salah satu bahan alternatif berupa filler untuk campuran aspal beton. Abu ampas tebu memiliki sifat khusus yaitu mengandung senyawa kimia yang bersifat pozzolan. Tujuan penelitian ini yaitu untuk mengetahui pengaruh penggunaan abu ampas tebu sebagai substitusi sebagian semen terhadap campuran laston AC-BC berdasarkan Uji Marshall. Penelitian ini menggunakan metode kuantitatif dengan eksperiman di laboratorium. Penelitian ini menggunakan variasi abu ampas tebu 0%, 5%, 10%, 15%, dan 20% terhadap berat semen tanpa mengubah kadar aspal dengan pembuatan masing-masing variasi 3 benda uji dan jumlah 15 benda uji yang ditambahkan pada berat filler. Abu ampas tebu berasal dari PG. Madukismo, Kasihan, Bantul. Hasil penelitian diperoleh nilai kadar aspal optimum 8,5% untuk nilai karakteristik Marshall pada nilai Density, VMA, VIM, VFB, Stabilitas, Flow, dan Marshalll Quotient pada variasi presentase 0%, 5%, 10%, 15%, dan 20% memenuhi spesifikasi sedangkan nilai VIM pada presentase 20% yang tidak memenuhi spesifikasi.</em>
MODEL MEDIA PEMBELAJARAN PENDIDIKAN AGAMA ISLAM MENURUT HADIST SERTA AKTUALISASINYA
Authors: Ihsan Muhammad Taufik 
Published: December 2023

Tujuan dari Pendidikan untuk mengembangkan aspek batin/rohani dan jasmani/lahiriyah. Realitas di masyarakat membuktikan pendidikan belum mampu menghasilkan anak didik berkualitas secara keseluruhan. Kenyataan ini dapat dicermati dengan banyaknya perilaku tidak terpuji terjadi di masyarakat, oleh sebab itu perlu adanya model media pembelajaran yang relevan menurut hadist serta aktualisasinya. Metode penelitian ini dilakukan dengan menggunakan studi pustaka dengan menelusuri berbagai rujukan yang terkait dengan topik utama permasalahan. Strategi analisis yang digunakan adalah dengan memfokuskan pada interpretasi dan kontekstualisasi. Adapun yang dianalisis adalah (1) Alat dan Media Pendidikan menurut Hadist (2) Media Pembelajaran Visual (3) Aktualisasi Media Pembelajaran Visual dalam Pendidikan. Adapun hasil pembahasannya adalah Rasulullah SAW menjadikan dirinya sebagai media pembelajaran, kemudian juga menjelaskan bahwa beberapa media pembelajaran visual seperti menggunakan gambar, menggunakan jari, menggunakan kerikil. Aktualisasi dari media pembelajaran visual dalam Pendidikan yakni keteladanan, perintah dan larangan serta ganjaran dan hukuman.
Keyword: Media pembelajaran, Pendidikan, Hadist, Aktualisasi