bluuebunny/crossref_metadata_2025_split huggingface dataset:
FORMALIZATION OF THE CULTURAL HERITAGE MANAGEMENT MODEL AS A FACTOR OF TOURISM DEVELOPMENT IN THE RUSSIAN FEDERATION
Authors: Ibragimov Ernest E. , Avdil’ Ibraim E. 
Published: December 2023

The article formalizes the model of cultural heritage management, clarifies the content of cultural heritage cognition by considering the processes of studying, preserving and using cultural heritage objects as a factor in the development of tourism in the Russian Federation, taking into account modern challenges and opportunities.
The preservation of cultural heritage and its rational use have a key role and importance for attracting tourist flows and improving socio-economic indicators and sustainable development of the region. In this regard, the importance of highlighting the internal structure of the cultural heritage management process as a factor in the development of tourism in the Russian Federation is actualized.
The purpose of the study: to formalize the model of cultural heritage management as a factor of tourism development in the Russian Federation.
The research methodology is represented by a set of general scientific and special historical methods of scientific cognition, the principles of historicism, scientific, systematic and complex.
The scientific novelty consists in an attempt to comprehensively comprehend the problem of studying, preserving and using Russian cultural heritage objects based on the analysis of contemporary research on the subject, taking into account modern realities and formalizing the model of cultural heritage management as a factor in the development of tourism.
The model of cultural heritage management as a factor of tourism development in the Russian Federation is formalized. The main reserves for improving the efficiency of cultural heritage management as a factor of tourism development are improving the quality of tourist products in the field of cultural and educational tourism; combining material and intangible parts of cultural heritage; developing eventfulness in the regions; creating an authentic environment in Russian tourist locations; branding cultural heritage sites and territories of their placement; using a wide range of digital technologies to promote and involve cultural heritage objects in the tourism industry; training professional personnel to work in the cultural and educational tourism industry.
Cidades Amazônicas no Período da Borracha A breve e trágica história de Santo Antônio do Madeira
Authors: Teixeira Marco Antônio Domingues 
Published: December 2023

Este trabalho aborda a criação e extinção do município de Santo Antônio do Madeira. Colonizada, há milênios, por Indígenas, a localidade tomou uma lúgubre fama ao ser considerada a cidade mais insalubre do mundo, segundo o Higienista Oswaldo Cruz que a visitou em 1910, no auge de uma pandemia de malária. Desde 1722, tentou-se estabelecer a colonização portuguesa na região, criando condições que permitissem o trânsito das “monções que pelo rio. Foram tentativas frustradas. No século XIX a região já havia sido abandonada, pelos colonizadores, diversas vezes. No século XX, Santo Antônio retomou sua importância como ponto de recebimento e reembarque da borracha boliviana, do Guaporé e do Mamoré. Em 1913 a cidade era fundada, pelo governo do Mato Grosso e em 1943 anexada ao recém criado Território Federal do Guaporé, desaparecendo em 1945. A metodologia deste trabalho parte da pesquisa bibliográfica, documental e de campo, com visitas ao sítio da cidade, hoje inexistente. Os resultados revelam sua inviabilidade, mas a localidade sempre foi e continua sendo um ponto nevrálgico na história das relações das sociedades locais com o rio. A pesquisa compreende os últimos 300 anos, e estende-se da ocupação colonial portuguesa à construção da Hidrelétrica de Santo Antônio.
APLICACIÓN DE LA INTELIGENCIA ARTIFICIAL EN LA TOMA DE DECISIONES JURISDICCIONALES (ESPAÑA)
Authors: Jiménez Cardona Noemí 
Published: December 2023

En un contexto de digitalización, robotización y algoritmización de la justicia, el presente artículo se centra en el análisis de la aplicación de la inteligencia artificial en la toma de decisiones jurisdiccionales, con especial referencia, de una parte, a las propuestas derivadas del Grupo de Trabajo del CGPJ sobre Tecnología, IA y Administración de Justicia (España) y, de otra, a la exposición de algunos ejemplos de aplicación práctica experimental de la inteligencia artificial y la digitalización en el ámbito del Derecho Mercantil, así como a la ponderación de las ventajas y riesgos inherentes a la mediación híbrida, a medio camino entre la mediación humana y la mediación robotizada.
Prevalência e fatores associados à hesitação vacinal infantil em área metropolitana do Nordeste Brasileiro
Authors: Lima Joseanna Gomes , Queiroz Rejane Christine de Sousa , Trindade Thiago Gomes da , Sales Jaqueline Jaqueline Carvalho e Silva , Kolling Ana Francisca , Soares Maria Sueli Marques , Chaves Lucieli Dias Pedreschi , Silva Ilana Mirian Felipe 
Published: December 2023

Estimar a prevalência à hesitação vacinal infantil e analisar fatores associados entre familiares/cuidadores. Estudo transversal com 246 familiares usuários da Atenção Primária à Saúde de um município da região metropolitana do estado do Maranhão, no Nordeste Brasileiro, entre janeiro e julho de 2022. Para avaliar a hesitação vacinal infantil, aplicou-se questionário sociodemográfico e de atitudes para COVID-19, além do instrumento Strategic Advisory Group of Experts Working Group on Vaccine Hesitancy. Realizaram-se análises descritivas e de associação por regressão linear múltipla. Um quarto (25,2%) dos familiares apresentou comportamento compatível à hesitação vacinal infantil. Pouco menos da metade das crianças (47,6%) estava com suas carteiras de vacinação atualizadas. Menos da metade dos entrevistados (42,7%) havia recebido duas doses para COVID-19 e apenas 58,5 % destes tinham a intenção de vacinar a criança para COVID-19. A maioria dos familiares hesitantes e não hesitantes (67,7% e 100%) concordou fortemente, respectivamente, que as vacinas são importantes. Porém, a maior parte destes concordou fortemente (91,9% e 93,5%) que se preocupa com as reações graves das vacinas. Dentre os indivíduos não hesitantes, 50% (n=92) concordaram fortemente que suas crianças não precisam de vacinas para doenças que não são mais comuns atualmente. Os fatores que permaneceram associados à hesitação vacinal infantil entre os participantes foram ter o estado civil solteiro (OR =2,03 p=0,039) e ter adesão à vacinação para COVID-19 (OR = 0,10 p<0,001). A prevalência de hesitação vacinal infantil foi elevada e os achados podem ajudar a compreender os principais fatores relacionados à recusa de vacinação.
O VOTO FEMININO EM DISPUTA DURANTE AS ELEIÇÕES DE 1933, NO CEARÁ
Authors: Almeida Custódio da Silva Larissa 
Published: December 2023

Este artigo objetiva discutir a ressignificação das disputas em torno do voto das mulheres durante as eleições de 1933, no Ceará, a partir da análise das estratégias de arregimentação do eleitorado feminino pelos dois partidos políticos vitoriosos no pleito: Liga Eleitoral Católica (LEC) e Partido Social Democrático (PSD). Através de seus respectivos porta-vozes na imprensa, jornais O Nordeste e O Povo, será possível esmiuçar como a cidadania política feminina, tornada realidade a partir de 1932, converteu-se numa nova arena de lutas devido ao seu potencial político de definição dos resultados: quais discursos e representações foram mobilizados para apresentar e representar as mulheres em suas plataformas políticas, bem como os espaços de poder reservados à parcela feminina apta para o voto a partir da nova dinâmica eleitoral.
Propagating ‘Chinese invention’ through landscape performing art: sublimating the arts to nationalism
Authors: Liu Quan 
Published: December 2023

Landscape performing arts (LPA) is a series of large-scale performances that was developed in China. The performances use natural scenery in open-air theatres, characterized by fixed locality and daily performances, coupled with spectacular visual and audio effects using modern stage technologies. They employ hundreds of local amateur performers who display their traditional culture through music and dance to both domestic and international tourists. Chinese media present the LPA form of theatre as a ‘Chinese invention’. The general concept of LPA highlights the Chinese traditional philosophy of harmony between humans and nature, and the traditional aesthetic shanshui (mountain water) to evoke a quintessential ‘Chinese’ scene, essence and tradition. The first 2003 performance of Impression Liu Sanjie has spawned a colossal LPA industry, each LPA adopting regional cultural characteristics. LPA has become a national brand for Chinese theatre. The format is internationalizing (it has been exported to Vietnam and Malaysia, for example), thereby allowing China to assist other countries in developing their cultural tourism industry.
This paper examines how the power of the Chinese landscape has been exploited by the party-state to propagate Chinese invention through LPA. One critical question about the development of the creative industry in China involves the paradox between mobilization (encouraging public creativity) and control (limiting liberality of ideology). China’s authorities in the reign of President Xi have focused on both strategies simultaneously. To explore the underlying principle of this seemingly self-contradictory policy, LPA is used to analyse the nationalistic affirmation of ‘Chinese invention’. The paper appropriates theories related to landscape and the sublime. Concepts relating to the sublime from Kant, Burke, Li Zehou and Wang Ban will be employed as theoretical instruments to deconstruct the notion of ‘Chinese invention’ within LPA and to expose the misguided discourse and nationalistic propaganda created to justify and promote it.
The research finding is that, on the one hand, the sublime emotionality of Chinese invention centres and unifies the loose contingency of individual experiences and the heterogeneity of subject-positions in the interest of covertly resolving the tension between mobilization and control of the creative industry. On the other hand, it cultivates aggressive individual and collective voices recruited in the party-state’s interest while resisting foreign forces. Arguably, hegemonic sensations are fabricated by the state apparatus in the country’s cultural landscape in order to cultivate belief in the inventiveness of the nation.
Oleic acid and linoleic acid nanosomes boost immunity and provoke cell death via the upregulation of beta-defensin-4 at genetic and epigenetic levels
Authors: Harisa Gamaleldin I. , Najashi Ibrahim , Bakheit Ahmed H. , Attia Sabry M. , Alanazi Fars K. , Al-Rejaie Salim S. , Mohany Mohamed 
Published: December 2023

Abstract
Host defense peptides (HDPs) are encouraged as anticancer and antimicrobial agents. Thus, this study aimed to investigate the effect of oleic acid (OA)- and linoleic acid (LA)-loaded nanosomes on the gene expression of beta-defensin-4 (BD-4) as a member of HDPs. The OA and LA nanosomes were prepared and characterized in terms of particle size and surface charge as lymphatic delivery systems. Afterwards, the effect of fatty acid (FA)-loaded nanosomes on BD-4 gene expression in mice dermal cells was investigated using polymerase chain reaction at 6, 12, and 24 h intervals. The epigenetic effect of OA and LA on histone deacetylase-6 (HDAC6) was studied using the molecular operating environment (MOE) docking. Moreover, the cytotoxic effect of free and FA-loaded nanosomes was investigated using 375 cell lines. The present results indicated that the prepared OA and LA nanosomes have a nanosize range (258–275 nm), negative zeta potential (−26 to −32 mV), and are homogenous polydispersity index (0.200–0.400). Moreover, free, and FA-loaded nanosomes induced significant upregulation of BD-4 mRNA expression after 6 and 12 h compared to the control mice BD-4 gene expression by several folds. However, after 24 h, the BD-4 mRNA expression significantly decreased compared to 12 h. Molecular docking studies revealed that OA and LA inhibit HDAC6 by binding with the active site. Treating the melanoma cell line with free or OL- and LA-loaded nanosomes induced significant cell death compared to negative control. This study suggests new insight into the effect of OA and LA on HDPs production. Consequently, the consumption of oils enriched with OL and LA stimulates the host immune system to fight microbial invasion and cancer. Moreover, Nanosomes are suggested as influential tactics for the specific lymphatic delivery of cytotoxic medicines.
Results on the modified degenerate Laplace-type integral associated with applications involving fractional kinetic equations
Authors: Almalki Yahya , Abdalla Mohamed , Abd-Elmageed Hala 
Published: December 2023

Abstract
Recently, integral transforms are a powerful tool used in many areas of mathematics, physics, engineering, and other fields and disciplines. This article is devoted to the study of one important integral transform, which is called the modified degenerate Laplace transform (MDLT). The fundamental formulas and properties of the MDLT are obtained. Furthermore, as an application of the acquired MDLT, we solved a simple differential equation and fractional-order kinetic equations. The outcomes covered here are general in nature and easily reducible to new and known outcomes.
Pharmacokinetic assessment of rifampicin and des-acetyl rifampicin in carbon tetrachloride induced liver injury model in Wistar rats
Authors: Sharma Swati , Anand Aishwarya , Taneja Sunil , Sharma Vishal , Bhatia Alka , Patil Amol N. , Banerjee Dibyajyoti 
Published: December 2023

AbstractObjectivesPreclinical evidence is needed to assess drug-metabolite behaviour in compromised liver function for developing the best antitubercular treatment (ATT) re-introduction regimen in drug-induced liver injury (DILI). The pharmacokinetic behavior of rifampicin (RMP) and its active metabolite des-acetyl-rifampicin (DARP) in DILI’s presence is unknown. To study the pharmacokinetic behavior of RMP and DARP in the presence of carbon tetrachloride (CCl4) plus ATT-DILI in rats.MethodsThirty rats used in the experiment were divided equally into six groups. We administered a single 0.5 mL/kg CCl4intraperitoneal injection in all rats. Groups II, III, IV, and V were started on daily oral RMP alone, RMP plus isoniazid (INH), RMP plus pyrazinamide (PZA), and the three drugs INH, RMP, and PZA together, respectively, for 21-days subsequently. Pharmacokinetic (PK) sampling was performed at 0, 0.5, 1, 3, 6, 12, and 24 h post-dosing on day 20. We monitored LFT at baseline on days-1, 7, and 21 and sacrificed the rats on the last day of the experiment.ResultsATT treatment sustained the CCl4-induced liver injury changes. A significant rise in mean total bilirubin levels was observed in groups administered rifampicin. The triple drug combination group demonstrated 1.43- and 1.84-times higher area-under-the-curve values of RMP (234.56±30.66 vs. 163.55±36.14 µg h/mL) and DARP (16.15±4.50 vs. 8.75±2.79 µg h/mL) compared to RMP alone group. Histological and oxidative stress changes supported underlying liver injury and PK alterations.ConclusionsRMP metabolism inhibition by PZA, more than isoniazid, was well preserved in the presence of underlying liver injury.
MHz repetition rate femtosecond radially polarized vortex laser direct writing Yb:CaF2 waveguide laser operating in continuous-wave and pulsed regimes
Authors: Liu Kaixin , Dong Yue , Zhang Zihao , Duan Xinghao , Guo Ruohao , Zhai Zhongjun , Wang Junli 
Published: December 2023

Abstract
In this paper, we report the use of femtosecond radially polarized vortex laser with MHz repetition rate for direct writing of cladding waveguides (WGs) and realization of waveguide laser oscillations in ytterbium-doped calcium fluoride crystal. The negative refractive index modification in Yb:CaF2 crystal is fabricated by the homemade all-fiber laser amplifier. At 976 nm pump wavelength, these Yb:CaF2 WGs can achieve continuous-wave (CW) laser oscillation. The length of resonant cavity is 4 mm, and the minimum laser threshold is 116 mW, corresponding to the propagation loss of 0.85 dB/cm, the center wavelength of 1045.2 nm, and the maximum output power of 91 mW. In addition, a saturable absorber mirror (SAM) was prepared by depositing ReS0.8Se1.2 on the reflective surface of a dichroic mirror to realize Q-switched waveguide laser output. The output Q-switched pulses with a tunable repetition rate in the range of 125–692.5 kHz, and the shortest pulse duration is 513 ns.
Finding the ‘Goldilocks Zone’: cationic size and tilting of carbodiimide and cyanamide anions
Authors: Medina-Jurado Juan , Corkett Alex J. , Dronskowski Richard 
Published: December 2023

Abstract
Solid-state carbodiimides and cyanamides are a group of compounds that generally shows motifs of layered structures, with an alternating sequence of metal cations and NCN2− anions. A study of the relationship between the ionic sizes in the cation layer and the crystal structures found is presented using the geometric characteristics of the NCN2− coordination environment. The results of this analysis reveal a ‘Goldilocks zone’ of cationic sizes, from Al3+ to Tl+, that are capable of forming stable “layered” metal carbodiimide structures. Furthermore, by employing a vectorial approach a correlation between the size difference of the cations and the degree of tilting of the NCN2− framework has been found, capable of predicting the likelihood of new phases crystallizing in such structures.
Theoretical and experimental approach on investigation of ethylurea-water clusters
Authors: Kazachenko Aleksandr S. , Holikulov Utkirjon , Issaoui Noureddine , Al-Dossary Omar M. , Ponomarev Ilya S. , Kazachenko Anna S. , Akman Feride , Bousiakou Leda G. 
Published: December 2023

Abstract
Alkylated urea derivatives have found wide application as starting materials for the production of many drugs, including anticancer drugs, as well as in many other areas. In this work, we studied ethylurea crystalline hydrates using a complex of theoretical and experimental methods. The nature of the intermolecular interactions between ethylurea and water molecules is investigated using topological analyses such as atoms in molecules (AIM), non-covalent interaction (NCI), reduced density gradient (RDG), electron localized functions (ELF), and localized orbital locator (LOL). The hydrogen bond energy is in the range of 1.1295–14.4327 kcal/mol. Also, a highly correlated parabolic relationship between topological parameters (E
HB, ρ, and ∇2
ρ) and H-bond length was determined. According to RDG data, with an increase in the number of water molecules in ethylurea clusters, the area corresponding to hydrogen bonds increases. The initial ethylurea and its crystalline hydrate were studied by FTIR spectroscopy and X-ray diffraction. The introduction of water molecules into the ethylurea crystal was proved by IR spectroscopy by the appearance of the corresponding absorption bands. X-ray diffraction showed that the initial ethylurea has intense peaks at 11.2, 16.8, 21.4, 22.24, 25.06, 25.78° 2Ɵ, the intensity of which changes when water molecules are introduced into the crystal.
BİRLEŞİK ARAP EMİRLİKLERİ’NDE VERGİ KLİNİĞİ VE TÜRKİYE’DE UYGULAMA OLASILIĞI
Authors: SAMANCI Muhammed 
Published: December 2023

Kamu kesiminin sunmuş olduğu hizmetlerin en önemli finansman kaynağı olan vergiler, toplumsal
hayatta yer almanın bir bedeli ve karşılığı bulunmayan bir mali yükümlülük olarak değerlendirilmektedir.
Türkiye Cumhuriyeti Anayasasında, mali güce göre herkesten vergi alınması gerektiği belirtilmiştir.
Vergi bilinci ve kültürünün yerleştiği toplumlarda bireylerin elde ettikleri gelirlerinin bir kısmının
devletle paylaşması gönüllülük esasına dayanarak gerçekleşmektedir. Bu gönüllülüğü devam ettirmek
ve vergiye uyumu artırmak amacıyla Amerika Birleşik Devletleri’nde ilk olarak başlatılan vergi kliniği
faaliyetleri daha sonra diğer ülkelere yayılmıştır. Bu çalışmanın amacı Birleşik Arap Emirlikleri’nde
vergi bilinci ve vergi uyumunu artırmak amacıyla Federal Vergi Dairesinin vergi kliniği tecrübesine
değinerek, Türkiye’de uygulanması veya vergi haftasına uyarlanmasıdır. Vergi Kliniği uygulamasında
en dikkat çekici yönü Federal Vergi Dairesinden uzman memurların üç ay boyunca bu etkinliğe
katılması ve çeşitli kamu kurum ve kuruluşlar ile özel sektör temsilcilerinin bu etkinlikte yer almasıdır.
Türkiye’de düzenlenen vergi haftasında bahsi geçen hususlar dikkate alınmamıştır. Ülkemizde vergi
bilinci ve vergiye uyumu artırmak için vergi haftasını bu yönde geliştirme çabaları başlatılması birinci
seçenek olarak değerlendirilebilir. İkinci seçenek ise, Türkiye’deki mevcut etkinliğe ek olarak, Hazine ve
Maliye Bakanlığı ve bazı kurumlardaki uzmanlarla iş birliği yapılarak BAE’deki vergi kliniğine benzer bir
uygulamanın hayata geçirilmesidir.
TÜRK HİSSE SENEDİ PİYASASINA İLİŞKİN DİNAMİK AĞ ANALİZİ
Authors: ÖZDEMİR Hüseyin 
Published: December 2023

Bu makale, COVID-19’un Borsa İstanbul’da işlem gören ve piyasa değeri 1 milyar doların üzerinde olan
48 firma arasındaki dinamik ağ yapısını incelemektedir. Getiri verileri günlük frekansta olup 1 Ocak 2017
tarihi ile 31 Mayıs 2022 arası dönemi arasında yer almaktadır. Standart VAR modelinden elde edilen
net ikili bağlantılılık endeksi sonuçları kullanılarak düğümler arasındaki yönlendirilmiş ağ yapısı ortaya
çıkarılmıştır. Modüler kümeleme yöntemi kullanılarak elde edilen ampirik bulgular COVID-19 salgını
öncesinde analize konu 48 firma hisse getirisinin üç alt grup altında toplandığını göstermektedir.
Pandeminin ortaya çıkmasından sonra söz konusu hisse senedi getirileri arasındaki küme sayısı dörde
çıkmaktadır. Faaliyet alanlarına göre 22 farklı sektörde bulunan söz konusu hisse senedi getirilerinin 3
ya da 4 alt grup ile hareket etmesi hisse senetlerinin sektörel etkilerden çok finansal etkiler ile hareket
ettiği gerçeğini doğrulamaktadır. Örneğin, otomotiv sektörüne ait şirketlerin her iki dönemde de
farklı gruplar altında yer aldığı görülmektedir. Salgın sonrasında birçok hisse senedinin ait olduğu
gruplar değişmiştir. Bu da hisse senetleri arasındaki ilişkilerin statik olmayıp dinamik ve değişken bir
yapıya sahip olduğunu göstermektedir. Ayrıca, bu ağ yapısı içinde, bankacılık sektörünün merkezi bir
rol oynadığına ilişkin önemli kanıtlar elde edilmiştir. Son olarak, COVID-19 salgını sonrasında hisse
senetleri arasındaki getiri korelasyonunun arttığı gözlemlenmiştir.
KURUMSAL RİSK YÖNETİMİ VE FİRMA PERFORMANSI: BORSA İSTANBUL ÜZERİNE BİR İNCELEME
Authors: MENGEŞ Ersin , AYGÜN Mehmet 
Published: December 2023

Risk yönetimi sürekli gelişen ve değişen bir disiplindir. Kurumsal risk yönetimi (KRY), kurumların başarı
olasılığını artırmak, başarısızlık olasılığını da azaltmak amacıyla tüm riskleri anlamak, değerlendirmek
ve bunlarla ilgili önlemler almak üzere yapılan girişimlerin bütünü olarak tanımlanabilmektedir.
Bu çalışmanın temel amacı, KRY ve firma performansı ilişkisini incelemek ve Borsa İstanbul’da faaliyet
gösteren 146 firmanın 2020-2021 yıllarına ait verilerinden yararlanarak bunu gerçekleştirmektir.
Çalışmada kurumsal risk yönetimi ölçümü olarak Gordon vd (2009) tarafından geliştirilen ve konuya
ilişkin yapılan çalışmalarda sıklıkla kullanılan model kullanılmıştır. Çalışmada firma performans
göstergesi olan muhasebe temelli (karlılık) ile piyasa temelli (getiri) değişkenleri ele alınmıştır. Yapılan
amprik analiz sonucunda KRY ile firma performans göstergeleri arasında ilişkinin kârlılık değişkeni
üzerinde hem olumlu ve istatistiki açıdan anlamlı olduğu sonuçlanmıştır.