bluuebunny/crossref_metadata_2025_split huggingface dataset:
Does in-vehicle automation help individuals with Parkinson’s disease? A preliminary analysis
Authors: Giang Wayne C.W. , Zheng Haolan , Gibson Beth , Patel Bhavana , Ramirez-Zamora Adolfo , Winter Sandra , Jeghers Mary , Li Yuan , Classen Sherrilene 
Published: October 2023

IntroductionPD is a progressive neurodegenerative disorder that affects, according to the ICF, body systems (cognitive, visual, and motor), and functions (e.g., decreased executive functions, decreased visual acuity, impaired contrast sensitivity, decreased coordination)—all which impact driving performance, an instrumental activity of daily living in the domain of “Activity” and “Participation” according to the ICF. Although there is strong evidence of impaired driving performance in PD, few studies have explored the real-world benefits of in-vehicle automation technologies, such as in-vehicle information systems (IVIS) and advanced driver assistance systems (ADAS), for drivers with PD. These technologies hold potential to alleviate driving impairments, reduce errors, and improve overall performance, allowing individuals with PD to maintain their mobility and independence more safely and for longer periods. This preliminary study aimed to fill the gap in the literature by examining the impact of IVIS and ADAS on driving safety, as indicated by the number of driving errors made by people with PD in an on-road study.MethodsForty-five adults with diagnosed PD drove a 2019 Toyota Camry equipped with IVIS and ADAS features (Toyota Safety Sense 2.0) on a route containing highway and suburban roads. Participants drove half of the route with the IVIS and ADAS systems activated and the other half with the systems deactivated.ResultsThe results suggest that systems that assume control of the driving task, such as adaptive cruise control, were most effective in reducing driving errors. Furthermore, individual differences in cognitive abilities, particularly memory, were significantly correlated with the total number of driving errors when the systems were deactivated, but no significant correlations were present when the systems were activated. Physical capability factors, such as rigidity and bradykinesia, were not significantly correlated with driving error.DiscussionTaken together, these results show that in-vehicle driver automation systems can benefit drivers with PD and diminish the impact of individual differences in driver cognitive ability.
Effect of adjuvant radiotherapy after breast-conserving surgery in elder women with early-stage breast cancer: a propensity-score matching analysis
Authors: Han Tingting , Shi Mingwei , Chen Qiwei , Chen Dongbo , Hao Jiqing 
Published: October 2023

PurposeThe study aimed to explore the role of adjuvant radiotherapy (RT) after breast-conserving surgery (BCS) in elder women with early-stage breast cancer (BC).MethodsBC patients with 70-79 years of age, stage T1‐2N0‐1M0, undergoing BCS were screened in the Surveillance, Epidemiology and End Results (SEER) database between 2010 and 2015. The clinicopathological characteristics were balanced with propensity-score matching (PSM) method. Kaplan–Meier curves and Cox regression analyses were performed to determine the impact of adjuvant RT on BC patients.ResultsUltimately, 12,310 patients treated with adjuvant RT and 4837 patients treated with no RT, were involved in the analysis. Overall, patients treated with adjuvant RT was associated with a better breast cancer-specific survival (BCSS) (HR: 1.980 [1.596- 2.456], P &lt; 0.001) and overall survival (OS) (HR: 2.214 [1.966- 2.494], P &lt; 0.001) than those who did not undergo RT. After 1:1 PSM, adjuvant RT still performed advantage in both BCSS (HR: 1.918 [1.439- 2.557], P &lt; 0.001) and OS (HR: 2.235 [1.904- 2.624], P &lt; 0.001). In the multivariate COX analysis of BCSS, widowed, divorced and separated patients, tumor grade III, T2 stage, N1 stage, no RT, molecular subtypes with luminal B and triple negative were associated with a shorter BCSS (P &lt; 0.05). In the multivariate COX analysis of OS, age ≥74 years, widowed, divorced and separated patients, tumor grade II/III, T2 stage, no RT, no chemotherapy, molecular subtypes with triple negative were associated with a shorter OS (P &lt; 0.05). Furthermore, the advantages of adjuvant RT were observed in all subgroup analysis.ConclusionAdjuvant RT after BCS can improve both BCSS and OS in elderly patients with early-stage BC. Additionally, all subgroups analysis-derived BCSS and OS were in support of RT.
Reimbursement decision-making system in Poland systematically compared to other countries
Authors: Mela Aneta , Rdzanek Elżbieta , Jaroszyński Janusz , Furtak-Niczyporuk Marzena , Jabłoński Mirosław , Niewada Maciej 
Published: October 2023

Introduction: Our objective was to analyze and compare systematically and structurally reimbursement systems in Poland and other countries.Methods: The systems were selected based on recommendations issued by the Polish Agency for Health Technology Assessment and Tariffication (AHTAPol), which explicitly referred to other countries and agencies). Consequently, apart from Poland, the countries included in the analysis were England, Scotland, Wales, Ireland, France, Netherlands, Germany, Norway, Sweden, Canada, Australia and New Zealand. Relevant information and data were collected through a systematic search of PubMed (Medline), Embase and The Cochrane Library as well as competent authority websites and grey literature sources.Results and discussion: In most of the countries, the submission of a reimbursement application is initiated by a pharmaceutical company, and only a few countries allow it before a product is approved for marketing. All of the agencies analyzed are independent and some have regulatory function of reimbursement decision making body. A key criterion differentiating the various agencies in terms of HTA is the cost-effectiveness threshold. Most of the countries have specific mechanisms to improve access to expensive specialty drugs, including cancer drugs and those used for rare diseases. Reimbursement systems often lack consistency in appreciating the same stages, leading to heterogeneous decision-making processes. The analysis of recommendations issued in different countries for the same medicinal product will allow a better understanding of the relations between the reimbursement system, HTA assessment, stakeholders involvement and decision on reimbursement of innovative drugs.
New terminology of medication adherence enabling and supporting activities: ENABLE terminology
Authors: Kardas Przemyslaw , Aarnio Emma , Agh Tamas , van Boven Job F. M. , Dima Alexandra Lelia , Ghiciuc Cristina Mihaela , Kamberi Fatjona , Petrova Guenka Ivanova , Nabergoj Makovec Urska , Trečiokienė Indrė 
Published: October 2023

Introduction: Medication non-adherence negatively affects the effectiveness of evidence-based therapies and sustainability of healthcare systems. Lack of agreed terminology of medication adherence enabling and supporting activities leads to underuse of the available tools. The ENABLE COST Action was aimed at proposing a new terminology for these activities in order to help both scientific research and its clinical application.Methods: Initial discussions within the ENABLE Working Groups allowed for the conceptualization of four interlinked terms related to adherence, i.e., “medication adherence technology”, “medication adherence enhancing intervention”, “best practice” and “reimbursement”. The iterative process of internal discussion was structured around two dedicated international workshops. Moreover, extensive stakeholder consultations have been organised, including an interactive online survey used to assess the level of agreement with, and the clarity of relevant terms and definitions proposed.Results: Detailed analysis of the results of this process allowed for fine-tuning of the items, and finally, for proposing the final set of definitions. Across all the three phases of this process, the definitions were substantially modified to better reflect the concepts, simplify the language, and assure completeness and cohesiveness of terminology. Feedback obtained from the stakeholders helped this process and confirmed that the final terms and definitions were well received by the experts active in the field of medication adherence.Discussion: Covering the gap in the existing terminology, this work proposes a cohesive set of terms and definitions applicable to medication adherence enabling and supporting activities. Promoting evidence-based approach to this field, this terminology may help research, clinical practice and policy.
In the Face of a Pandemic: “I Felt the Same as When the War Started”—A Qualitative Study on COVID-19 Vaccine Acceptance in Bosnia and Herzegovina
Authors: Bosankic-Cmajcanin Nina , Musa Sanjin , Draganovic Selvira 
Published: October 2023

Objectives: To conduct qualitative study with different target groups in Bosnia and Herzegovina in order to explore their views on barriers and drivers for COVID-19 vaccination, and to see if and how barriers and drivers vary between urban and rural locations, and different professional roles.Methods: The theoretical framework underpinning the study is the capability-opportunity-motivation (COM-B) behavior change framework, which has been adapted to monitor vaccine related behavior and attitudes. Data was collected from June to September 2022 through moderated discussions in focus groups. The total of 162 participants participated in 16 focus groups.Results: Among the key barriers to successful immunization identified across target groups were insufficient knowledge about vaccines, pandemic fatigue, concerns about the rapid development of the vaccine and its effectiveness, lack of confidence in the healthcare system. Some of the main drivers of vaccination against COVID-19 were confidence in science and expert recommendations.Conclusion: The COVID-19 immunization policy undergoes continuous changes, as do the pandemic prospects; we encourage further research to track the evolution of vaccine related attitudes, inform immunization policy, and create evidence-based interventions.
Numerical Study on the Flow and Structural Characteristics of a Large High Head Prototype Pump-Turbine under Different Operating Conditions
Authors: Ru Songnan , Zhang Shaozheng , Zhou Kaitao , Huang Xingxing , Huang Wenlong , Wang Zhengwei 
Published: October 2023

During the operation of pumped storage power stations, complex operating conditions can lead to different internal flow characteristics, which can cause different vibration characteristics or even damage to the structural components of the pump-turbine units. The time–frequency characteristics of the structural components’ response are of great significance for the safe operation of the unit. In this study, a three-dimensional flow field and structural field model of a large high head prototype pump-turbine is built in order to study the flow and the flow-induced dynamic response characteristics in different turbine operating conditions. The analyzed results show that the maximum deformation occurs at the inner head cover, and the maximum value of stress is located at the fillets on the outlet side of the stay vanes. Under the 50% load condition, the vortices in the runner caused by changes in the opening of the guide vanes result in the main response frequency of 4 fn of the stationary components. The research results can provide references for the structural optimization design of other pump-turbine units.
PECULIARITIES OF INTERPERSONAL INTERACTION OF FUTURE TECHNICAL PROFILE SPECIALISTS WITH DIFFERENT TYPES OF INTERACTIVE ORIENTATION
Authors: Kuksa Y. 
Published: October 2023

The article is devoted to the problem of interpersonal interaction creation by students of a technical profile. In particular, the results of a comparative study of the peculiarities of the interpersonal interaction creation by students of a technical profile with different types of interactive orientation are described.
In the article, interaction refers to any agreed action of two or more people. Among the conditions under which the existence and progress of interaction is possible, there are defined the mutual understanding of its participants and the awareness of each of the participants of their own contribution to the joint activity.
According to the results of the empirical study, it was found that although the technical profile students have a certain level of disharmony in interpersonal relationships, the relationships of more than half of them are mostly harmonious and stable in nature.. In addition, the diagnosis of the interactive orientation of the studied future technical profile specialists proved that the vast majority of students have an average level of orientation to personal interests and orientation to interaction and cooperation, and the level of marginal orientation among them is mostly high, that is, these students are characterized with manifestations of infantilism, uncontrollability of actions, imitation.
Determining the peculiarities of the interpersonal interaction creation by the technical profile students with different types of interactive orientation showed that the higher the level of manifestation of conflict in relationships students demonstrate, the more they are focused on pursuing their own goals exclusively. In addition, the more the studied students demonstrate an increased concern for relationships, the more these future technical profile students are characterized with manifestations of infantilism and uncontrollable actions. Also, the more students express a desire to distance themselves from other people, the more likely they are to simply obey to circumstances and behave impulsively. Thus the future specialists of technical profile with different types of interactive orientation are characterized with different specificity of interpersonal interaction creation.
DOUBLE ASPECT AND PECULIARITY OF THE PERSON DISEASE MANIFESTATIONS
Authors: Buniak N. , Shandruk S. 
Published: October 2023

The results of the analysis of psychological factor importance in the development and course of somatic pathology are considered in this paper.
The authors of this scientific publication point out that the symptoms of any disease can be a direct expression of mental experiences of the person and indicate the correct understanding of the disease as a process caused primarily by psychological factors and that the emotional state of the person affects both the occurrence and overcoming the disease , and the conventional line separating the concept of “organic disease of internal organs and systems” and “psychosomatic disorder” is rather blurred.
The importance of understanding the human organism as a complete self-regulating system in all its complexity of physical and mental manifestations and in close interdependence with specific life conditions for each person is noted.
The data of numerous investigations, which testify that psychosocial factors have significant impact on the occurrence and spread of diseases are summarized in this paper.
The importance of trusting the psychologist or doctor in the person’s attitude to disease, which is considered as the moral choice and gives permission to act in extremely difficult circumstances for the ill person is highlighted.
The authors emphasize the importance of mastering “Medical Psychology” discipline (or, in our opinion, “Psychology of Medicine”) by the students of higher educational institutions specializing in “Psychology”.
THE CONTRIBUTION MADE BY MYKOLA YARMACHENKO INSTITUTE OF SPECIAL EDUCATION AND PSYCHOLOGY OF THE NAES OF UKRAINE TO DEVELOPMENT OF THE THEORY AND PRACTICE OF SPECIAL PSYCHOLOGY
Authors: Kobylchenkо V. , Omelchenko I. 
Published: October 2023

The article examines and analyses the contribution made by Mykola Yarmachenko Institute of Special Education and Psychology of the National Academy of Educational Sciences of Ukraine to development of the theory and practice of special psychology.
The article highlights that Ukrainian special psychology faces the tasks to reflect methodologically and understand special psychology historical path and current status.
Special psychology was an integral part of defectology, was an applied branch of knowledge by its nature and was formed as a multi-disciplinary discipline.
After Ukraine had achieved independence, the issues regarding the theoretical and conceptual base of special psychology became really important, since the various areas of special psychology remained significantly detached from conducted applied research.
The article authors reviewed modern Ukrainian educational and methodological literature for higher education and revealed that the publications were mainly writhing the framework of classical psychology and defectology and based on the natural-scientific paradigm.
We also found that in recent years, psychological science had significant achievements in the field of special psychology due to the ever-increasing influence of the humanistic paradigm on the subject and methodology of psychological research.
The article describes the achievements of Mykola Yarmachenko Institute of Special Education and Psychology in the field of special psychology, its role and influence on special psychology development, its contribution to theory and practice.
Un habitat occupé du VIIe au XIIe siècle : Les Cinq-Chemins à Bauné (Maine-et-Loire)
Authors: David Florence , Valais Alain 
Published: October 2023

Eine Siedlung des 7.-12. Jhs. : Les Cinq-Chemins (Bauné, Maine-et-Loire). Die ländliche Siedlung der Cinq-Chemins wurde vor dem Bau der Autobahn A 85 (Angers-Tours) ausgegraben ; sie wurde vom 7. bis zum 12, Jh. bewohnt, wobei drei Besiedlungsphasen zu unterscheiden sind. Die erste (7. bis frühes 9. Jh.) ist am besten dokumentiert, mit einem Weg, einem Gräbensystem, Silos (oft gruppenweise), einem Kalkofen und Pfostenlöchern. In der zweiten Phase (9. bis frühes 11.Jh.) dünnt die Besiedlung merklich aus : nur etliche Silos und Pfostenlöcher haben sich erhalten. Die drei festgestellten Pfosten bauten können der ersten oder der zweiten Phase angehören. In der dritten und letzten Besiedlungsphase zeigt sich wieder mehr Aktivität, vor allem im östlichen Drittel der Grabungsfläche, um eine Gruppe von Silos.
Etwa 15 Rinder wurden entweder in Silos, oder in eigens dafür ausgehobenen Gruben verscharrt ; es zeigt die Auswirkungen von Viehseuchen auf mittelalterliche Herden.
Business Incubators: The Genesis, Growth, and Innovation Exhilarating
Authors: Ramar N. , Magheswari M. 
Published: October 2023

Business incubators have evolved over the years due to various factors such as global trends, economic needs, technical revolutions, and challenges. These incubators play a vital role in supporting young companies, helping them grow, and enhancing their commercial success. While the expansion of incubation models is well-recognized, there is limited awareness regarding how their value propositions have transformed over time. This study begins by tracing the origins of business incubation back to the 1950s. It then delves into the analysis of the development of business incubators, categorizing them into three generations using typology methodology. The first generation primarily focuses on achieving economies of scale; the second generation places a strong emphasis on providing knowledge-based services, and the third generation centersaround facilitating access to external resources, expertise, and legitimacy. The core focus of this study revolves around understanding how the value propositions and strategies of incubators should be tailored to address the current opportunities, challenges, and trends that entrepreneurs and startups are encountering in today’s dynamic business landscape.
PROSES PRODUKSI PENGOLAHAN PLASTIK POLYETHLENE DI PT. PLASTIK KARAWANG FLEXINDO
Authors: Ma'arif Dadan , Kardiman Kardiman 
Published: October 2023

Proses produksi adalah kegiatan menciptakan atau meningkatkan kegunaan suatu produk atau jasa sehingga lebih sesuai dengan kebutuhan manusia, dengan menggunakan faktor-faktor yang ada seperti tenaga kerja, mesin, bahan baku, dan modal. Proses produksi plastik pada umunya meliputi bebrapa tahapan seperti mixing dan blowing. Dalam proses produksi plastik mesin mixing mengaduk bahan kemudian di teruskan oleh mesin blowing untuk mengolah biji plastik menjadi bentuk akhir plastik berupa gulungan (roll). Bahan baku utama yang digunakan berupa biji plastik High Density Polyethlene (HDPE) dan Low Density Polyethlene (LDPE). Dalam proses pembuatan kantong plastik atau roll plastik tidak melulu mendapatkan hasil yang sempurna. Dengan demikian, kecacatan terhadap suatu produk dapat terjadi sewaktu-waktu dan oleh sebab itu maka dapat dicari sumber masalahnya. Dalam mengidentifikasi masalah, penulis menggunakan diagram fishbone guna mempermudah dalam mencari suatu akar permasalahan. Penelitian ini dilaksanakan pada bulan Maret-Mei 2022 di PT. Plastik Karawang Flexindo.
Kata Kunci: Proses Produksi; HDPE; LDPE; Diagram Fisbone
СПІВПРАЦЯ СОЦІАЛЬНИХ ПАРТНЕРІВ У ПІДГОТОВЦІ МАЙБУТНІХ МЕНЕДЖЕРІВ ЗА ДУАЛЬНОЮ ФОРМОЮ НАВЧАННЯ: ДОСВІД НІМЕЧЧИНИ
Authors: Опушко Надія 
Published: October 2023

Автором наголошено на важливості в будь-якій сфері життя соціального партнерства, заснованого на добровільній та взаємовигідній співпраці, спрямованій на досягнення його учасниками певних спільних цілей. Зазначено, що соціальне партнерство в професійній освіті – особливий тип взаємодії освітніх закладів з суб’єктами та інституціями ринку праці, державними та місцевими органами влади, громадськими організаціями, спрямоване на максимальне узгодження і врахування всіх учасників цього процесу. Формування системи соціального партнерства в сучасних соціально-економічних і політичних умовах – достатньо тривалий і складний процес, що залежить від цілої низки суб’єктивних та об’єктивних причин, а результативність та ефективність роботи залежить від закладу освіти з соціальними партнерами визначається ступенем реалізації своїх інтересів, що полягає, насамперед, в підготовці висококваліфікованих фахівців та оцінюється за ступенем виконання своєї основної соціальної функції. У статті запропоновано та проаналізовано цілі, форми й шляхи реалізації співпраці соціальних партнерів у підготовці майбутніх менеджерів за дуальною формою навчання на основі проаналізованого досвіду Баден-Вюртемберзького кооперативного державного університету (Duale Hochschule Baden-Württemberg (DHBW)). Акцентовано увагу на функціональних обов’язках кожного суб’єкту освітнього процесу як в закладі освіти, так і в компанії-партнері. Наголошено на значущості узгодженості співпраці між викладачами університету та організаторами практичного навчання на виробництві; встановлено беззаперечну корисність такої співпраці для майбутніх менеджерів.
Ключові слова: майбутніх менеджерів; соціальне партнерство; професійна освіта; закордонний досвід; дуальна освіта; Німеччина; Баден-Вюртемберзький кооперативний державний університет.