bluuebunny/crossref_metadata_2025_split huggingface dataset:
The geography of technological innovation dynamics
Authors: Straccamore Matteo , Loreto Vittorio , Gravino Pietro 
Published: November 2023

AbstractCities and metropolitan areas are major drivers of creativity and innovation in all possible sectors: scientific, technological, social, artistic, etc. The critical concentration and proximity of diverse mindsets and opportunities, supported by efficient infrastructures, enable new technologies and ideas to emerge, thrive, and trigger further innovation. Though this pattern seems well established, geography’s role in the emergence and diffusion of new technologies still needs to be clarified. An additional important question concerns the identification of the technological innovation pathways of metropolitan areas. Here, we explore the factors that influence the spread of technology among metropolitan areas worldwide and how geography and political borders impact this process. Our evidence suggests that political geography has been highly important for the diffusion of technological innovation till around two decades ago, slowly declining afterwards in favour of a more global patenting ecosystem. Further, the visualisation of the evolution of countries and metropolitan areas in a 2d space of competitiveness and diversification reveals the existence of two main technological innovation pathways, discriminating between different strategies towards progress. Our work provides insights for policymakers seeking to promote economic growth and technological advancement through tailored investments in prioritarian technological innovation areas.
Vitamin D status as a predictor for liver transplant outcomes
Authors: Fotros Danial , Sohouli Mohammadhassan , Yari Zahra , Sakhdari Hanie , Shafiekhani Mojtaba , Nikoupour Hamed , Jafarzadeh Mohammad Amin , Jafari Keynoosh , Afiatjoo Seyedeh Sara , Fatemi Seyed Amirreza , Amiri Mahmoud , Eghlimi Hesameddin , Rabbani Amirhassan , Broumandnia Nasrin , Mazdeh Ghazaleh Mahdavi , Jafarian Ali , Hekmatdoost Azita 
Published: November 2023

AbstractIt is well known that vitamin D plays a pivotal role in immune system modulation; however, its role in liver transplantation (LT) has not yet been well elucidated. This study aimed to assess the association between vitamin D status and LT outcomes. This retrospective cohort study was conducted on 335 registered cirrhotic patients with end-stage liver disease (ESLD) who underwent LT during 2019–2021 and had measurement of serum vitamin D before LT. The association of vitamin D levels before LT with the odds of acute cellular rejection (ACR) and risk mortality was assessed by applying logistic and cox regression, respectively. The mean MELD-Na and serum level of vitamin D were 20.39 ± 9.36 and 21.52 ± 15.28 ng/ml, respectively. In the final adjusted model, there was a significant association between vitamin D deficiency in the pre-transplant period and odds of ACR (odds ratio [OR] 2.69; 95% confidence interval [CI] 1.50–4.68). Although in the crude model, vitamin D deficiency in the pre-transplant period was significantly associated with an increased risk of mortality after two years of follow-up (Hazard ratio (HR) = 2.64, 95% CI 1.42–4.33), after adjustment for potential confounders, the association of vitamin D status and mortality became non-significant (HR = 1.46, 95% CI 0.71–3.00). The present study provides evidence that pre-transplant serum vitamin D levels may be a predictor for ACR in patients with cirrhosis undergoing LT.
Importance des études transnationales sur le curare dans le développement de la recherche en neurophysiologie au Brésil
Authors: Pereira Santos Roberto , Nardi Antonio Egídio , da Mota Gomes Marleide 
Published: November 2023

Le curare, un poison obtenu à partir de différentes espèces de plantes en Amérique du Sud, était utilisé sur les flèches par les autochtones. Son potentiel paralysant mortel et son mécanisme d’action ont commencé à être explorés par les chercheurs au XIXe siècle. Dans cet article, nous rappelons l’historique des recherches sur ce poison et les échanges entre l’empereur brésilien Dom Pedro II et les chercheurs João Baptista de Lacerda, Louis Couty et Alfred Vulpian qui ont beaucoup contribué au développement scientifique brésilien. Vulpian a découvert que le curare n’affecte pas le nerf lui-même, mais agit entre celui-ci et le muscle, par l’intermédiaire d’une « substance de liaison » – ce concept développé par Vulpian est souvent attribué à tort à Claude Bernard. Les travaux pionniers de ces savants prestigieux ont ultérieurement abouti à la préparation d’extrait purifié de curare, d’intérêt thérapeutique majeur pour le traitement de convulsions et pour l’anesthésie.
Thérapies ciblées et immunothérapies dans le mélanome
Authors: Braissand Nicolas , Coste Isabelle 
Published: November 2023

Dans le cadre d’un partenariat avec médecine/sciences, et pour la cinquième année consécutive, des étudiants du module d’enseignement « Immunologie, virologie et cancer » du Master Cancer de Lyon présentent une analyse d’articles scientifiques récents faisant état d’observations innovantes et importantes. Ce travail a été encadré par des chercheurs confirmés du Centre de Recherche en Cancérologie de Lyon (CRCL). Le master Cancer (université Claude Bernard Lyon1- VetAgroSup) accueille chaque année 40 étudiants en M1 et environ 80 en M2. Ce master dit « d’excellence » (master international labellisé université de Lyon) assure aux étudiants de M1 une formation en cancérologie reposant sur un socle de base commun (biologie cellulaire, moléculaire, immunologie, bio-statistique, épidémiologie, recherche translationnelle, etc.). Cette formation repose sur une forte implication des chercheurs et enseignants-chercheurs du CRCL, ainsi que sur un partenariat fort avec plusieurs instituts, dont le MIT (Massachusetts Institute of Technology, Cambridge, États-Unis), l’université d’Harvard (Boston, États-Unis), l’université de Californie à San Diego (UCSD) (États-Unis), la university of City of London (UCL), le Beatson Institute de Glasgow (Royaume-Uni), les universités de Shanghai Jiao Tong (République populaire de Chine, RPC), de Tokyo et Tohoku (Japon), de Melbourne (Australie) et d’Auckland (Nouvelle-Zélande).
Fréquence des malformations congénitales chez les chiots nés par césarienne
Authors: Tainturier Daniel , Brassié Marine , Topie Emmanuel 
Published: November 2023

Chez 1098 chiots nés par 235 césariennes sur une période de 8 ans, 118 présentaient une malformation congénitale visible dont 65 une fente palatine ou labio-palatine, 32 étaient atteints d’anasarque, 6 d’une hernie ombilicale et 15 d’une autre malformation.
L’anasarque est surtout observée chez le Bulldog anglais, les fentes palatines ne sont pas influencées par la race, mais de nombreuses malformations sont observées chez le Chihuahua.
L’éducation thérapeutique des maîtres lors d’affections hépatiques chroniques : l’ASV en première ligne
Authors: Desachy Florence 
Published: November 2023

L’éducation thérapeutique en milieu vétérinaire se développe. Elle permet un investissement professionnel de l’équipe d’ASV et une fidélisation de la clientèle anxieuse face aux pathologies chroniques.
Des étapes doivent être respectées pour une grande clarté et de solides connaissances sont nécessaires pour assurer l’éducation thérapeutique de la clientèle de la clinique. Celle-ci est essentielle pour améliorer l’observance et, de ce fait, le pronostic de l’animal.
Akupunktur beim Fibromyalgie-Syndrom
Authors: Böttcher Cornelia 
Published: November 2023

ZusammenfassungDas Fibromyalgie-Syndrom ist ein multifaktorielles Geschehen, das durch physische und physische Symptome gekennzeichnet ist. Wichtig bei der ärztlichen Behandlung bzw. Beratung ist, die Patient*innen in ihrem Schmerzgeschehen ernst zu nehmen, da Schmerz immer real ist. Aus Sicht der Chinesischen Medizin ist bei jeder Erkrankung das Gleichgewicht von Yin und Yang gestört und die Lebenskraft Qi kann nicht fließen. Die Chinesische Medizin sieht Störungen gleichermaßen auf der körperlichen und psychischen Ebene – es gibt keine Trennung. Um Qi wieder fließen zu lassen, kann die Akupunktur hilfreich sein. Die Akupunktur wirkt sowohl auf der psychischen als auch auf der körperlichen Ebene. Deshalb stellt sie beim FMS eine gute Ergänzung zu den übrigen Therapien dar. Die Begleitung von Patient*innen mit Fibromyalgie-Syndrom ist langwierig und erfordert neben Fachwissen auch den Blick über den Tellerrand.
Ganzkörperhyperthermie beim Fibromyalgie-Syndrom – Ergebnisse einer randomisierten kontrollierten Studie
Authors: Öznur Özlem , Langhorst Jost 
Published: November 2023

ZusammenfassungDas Fibromyalgie-Syndrom (FMS) ist eine chronisch-funktionelle Schmerzerkrankung, deren Behandlungssituation häufig als unzureichend empfunden wird. Für die milde wassergefilterte Infrarot-A-Ganzkörperhyperthermie (wIRA-GKHT) liegen erste vielversprechende Ergebnisse in der Therapie der FMS vor. In einer ambulanten randomisiertkontrollierten Studie wurden die Auswirkungen der GKHT im Vergleich zur sanften Ganzkörperhyperthermie auf die Schmerzintensität bei Patienten mit FMS untersucht. Insgesamt nahmen 41 Teilnehmer im Alter von 18–70 Jahren mit einer medizinisch bestätigten FMS-Diagnose teil. Die Behandlung bestand aus 6 Sitzungen mit wIRA-GKHT über einen Zeitraum von 3 Wochen. Die Kontrollgruppe erhielt die gleiche Behandlung, jedoch mit einem Bruchteil der Infrarot-A-Strahlung. Als primäres Outcome wurde die Schmerzintensität definiert, die signifikante Gruppenunterschiede zugunsten der GKHT-Gruppe zeigte. Weitere Ergebnisse umfassten die FMS-spezifischen Kernsymptome und die Lebensqualität sowie Zytokinwerte im Blut. Im Rahmen der Studie konnte gezeigt werden, dass die milde wassergefilterte Infrarot-A-Ganzkörperhyperthermie die Schmerzintensität von Patienten mit FMS effektiv reduziert.
Risk Profile of High-grade Cervical Lesions and Cervical Cancer Considering the Combination of Cytology, HPV Genotype, and Age among Women Undergoing Colposcopy
Authors: Possati-Resende Júlio César , Fritsch Thais Zilles , Souza Karen Cristina Borba 
Published: November 2023

Abstract
Objective The present study aims to establish a risk profile for high-grade cervical lesions and cervical cancer (CIN2 + ) in women undergoing colposcopy at the Hospital do Câncer de Barretos, through the analysis of Human Papillomavirus (HPV) infection, cervical cytology, and patient's age.
Methods Retrospective cross-sectional study based on a computerized database of women aged ≥ 18 years old who underwent colposcopy at the Prevention Department of the Hospital do Câncer de Barretos from 2017 to 2019.
Results A total of 3,411 women were included, 58.0% were positive for high-risk-HPV test, with a higher prevalence of CIN2+ for HPV16 (30.3%) and other HPV (45.0%). Cytological findings that suggest invasive cervical cancer (squamous cells or adenocarcinoma), regardless of the status of HPV test, showed 100% diagnosis of CIN2 + , while atypias that suggest high-grade lesions, HSIL and ASC-H, positive for HPV test, showed in 86 and 55.2%, respectively, diagnosis of CIN2 + . ASC-H cytological results among women aged > 40 years old and negative HPV were mainly associated with benign findings. We observed that ≤ CIN1 has a higher prevalence among older women with negative HPV, while for high-grade lesions there is an increase among young women HPV16- and/or 18-positive. In cancer diagnosis, we observed a predominance of HPV 16/18 regardless of the age group.
Conclusion The highest risks of precursor lesions and cervical cancer were found among women with positive HPV 16/18 tests and severe cytological atypia in population screening tests. In addition, cytological findings of ASC-H HPV negative in women > 40 years old usually represent benign findings in histological investigation.
Fetal Macrosomia and Postpartum Hemorrhage in Latin American and Caribbean Region: Systematic Review and Meta-analysis
Authors: Quezada-Robles Araceli , Quispe-Sarmiento Fiorella , Bendezu-Quispe Guido , Vargas-Fernández Rodrigo 
Published: November 2023

Abstract
Objective To determine the association between fetal macrosomia (FM) and postpartum hemorrhage (PPH) in Latin American and Caribbean (LAC) women.
Data Sources Studies evaluating the association between FM and PPH (≥ 500 ml) and severe PPH (≥ 1,000 ml) until November 4, 2021, indexed in CINHAL, Scopus, Embase, Cochrane Library, MEDLINE, LILACS, and SciELO.
Selection of Studies Inclusion criteria were cohort and case-control studies that provided the number of PPH and FM cases. Exclusion criteria were studies lacking information about the number of cases, with a population of women who were not from LAC; published in a language other than English, Spanish, or Portuguese, and with a different design.
Data Collection Data extraction was performed independently by two authors, and discrepancies were resolved with a third author. Data regarding FM and PPH cases were retrieved.
Data Synthesis Of the 1,044 articles evaluated, 5 studies were included, from 6 different countries: Argentina and Uruguay (multi-country), West Indies, Antigua and Barbuda, French Guyana, and Suriname. The pooled odds ratio (OR) for FM and PPH in the meta-analysis (five studies) was 2.10 (95% confidence interval [CI]: 1.79–2.47; I2: 0%), with estimates within this 95% CI in the sensitivity analysis. The combined OR for severe PPH (3 studies) was 1.61 (95% CI: 0.40–6.48; I2: 91.89%), showing high heterogeneity.
Conclusion There was a positive association between FM and PPH in the LAC, increasing the risk of the presence of this event 2-fold. The high heterogeneity of the studies that measured severe PPH does not allow drawing conclusions about the estimates obtained.
Effect of the dipolar interaction on the dynamic hysteresis properties of 2D-nanodisks: out of plane driving field case
Authors: Çam Necda , Akıncı Ümit 
Published: November 2023

Abstract
We have systematically investigated the effect of dipolar interaction strength on the dynamical hysteresis behavior of the in-plane uniaxial anisotropic nanodisk system modeled by the classical Heisenberg model under the effect of the time-dependent external out-of-plane periodic magnetic field. Dynamical hysteresis loops, as well as hysteresis quantities (hysteresis loop area, coercive field, remanent magnetization), have been examined both in-plane and out-of-plane magnetization components by means of Monte Carlo simulation based on Metropolis Algorithm. Our simulation results suggest that the response of the in-plane and out-of-plane components of the magnetization have different hysteresis characteristics. For instance, while the out-of-plane component of the magnetization has ordinary dynamically disordered hysteresis curves, bowtie-shaped hysteresis loops have been obtained for the in-plane component of the magnetization. Disappeared dynamical order has been observed with the rising strength of the dipolar interaction.
Measurement of the voltage evolution on a load of X-pinch plasma system using the Pockels effect
Authors: Choi Seongmin , Ham Seunggi , Ryu Jonghyeon , Park Sungbin , Kim Jung-Hwa , Choi YeongHwan , Chung Kyoung-Jae , Hwang Y.S. , Ghim Y.-c. 
Published: November 2023

Abstract
A diagnostic system using the Pockels effect (linear electro-optic effect) has been developed to measure a voltage on a load of the SNU X-pinch device [Ryu et al., Rev. Sci. Instrum. 92, 053533 (2021)]. The sensor component of the diagnostic system comprises of a lithium niobate (LN) crystal and its mount. When the LN crystal is subjected to an external electric field, the refractive indices of the LN crystal change due to the Pockels effect, leading to a change in the polarization state of the propagating laser beam through the crystal. This concept allows the separation and shielding of electronic devices from the intense electric pulses generated by the X-pinch system. Furthermore, the compact size and high electric field tolerance of the LN crystal enable us to position the sensor in a close proximity to the load of the X-pinch, facilitating the measurement of voltage evolution on the load. In contrast to circuit-based voltage probes, our sensor possesses low inductance, allowing us to measure resistive-dominant voltage even in the presence of rapid current changes within the X-pinch system. In this paper, we outline the configuration of our voltage measurement system using the LN crystal within the X-pinch device and provide measurement results of the load voltage. Additionally, we explore the temporal evolution of the voltage in relation to the phase transition of the load.
Urban growth modeling for the assessment of future climate and disaster risks: approaches, gaps and needs
Authors: Reimuth Andrea , Hagenlocher Michael , Yang Liang Emlyn , Katzschner Antje , Harb Mostapha , Garschagen Matthias 
Published: November 2023

Abstract
Urban climate-related disaster risks are set to rise, driven by the interaction of two global megatrends: urbanization and climate change. A detailed understanding of whether, where and how cities are growing within or into hazard-prone areas is an urgent prerequisite for assessing future risk trajectories, risk-informed planning, and adaptation decisions. However, this analysis has been mostly neglected to date, as most climate change and disaster risk research has focused on the assessment of future hazard trends but less on the assessment of how socio-economic changes affect future hazard exposure. Urban growth and expansion modeling provide a powerful tool, given that urban growth is a major driver of future disaster risk in cities. The paper reviews the achievements lately made in urban growth and exposure modeling and assesses how they can be applied in the context of future-oriented urban risk assessment and the planning of adaptation measures. It also analyses which methodological challenges persist in urban growth and exposure modeling and how they might be overcome. These points pertain particularly to the need to consider and integrate (1) urban morphology patterns and potential linkages to exposure as well as vulnerability, (2) long-term time horizons to consider long-term developments, (3) feedbacks between urbanization trajectories and hazard trends, (4) the integration of future urban growth drivers and adaptation responses, (5) feedbacks between adaptation and urbanization, and (6) scenarios, which are developed within a commonly defined scenario framework.
What drives historical and future changes in photovoltaic power production from the perspective of global warming?
Authors: Constantin Scheele Robert , Fiedler Stephanie 
Published: November 2023

Abstract
We investigate the drivers of global and regional changes in the potential for photovoltaic (PV) power production from the pre-industrial (1850) to present-day (1985–2014) and until the end of the century (2071–2100), based on output from the Coupled Model Intercomparison Project phase six (CMIP6). Our assessment separates regional contributions from changes in clouds, humidity, temperature, aerosols, and wind speed to the changes in PV power potentials for the first time. Present-day PV power potentials are adversely affected by anthropogenic aerosols compared to the pre-industrial, with a global decrease of the PV power potential by −1.3%. Our results highlight a globally averaged decrease in future PV power potentials primarily driven by temperature and humidity increases by −1.2% to more than −3.5%, depending on the scenario. Regionally different contributions of changes in clouds and aerosols cause heterogeneous spatial patterns in changes of PV potentials, with typically stronger (weaker) influences from clouds (aerosols) in SSP5-8.5 compared to SSP1-2.6. Our results imply that the uncertain response of clouds to warming and aerosol effects are hurdles in quantifying changes in the regional potentials for PV power production.
Paramagnetic two-dimensional silicon-oxide from natural silicates
Authors: Mahapatra Preeti Lata , de Oliveira Caique Campos , Costin Gelu , Sarkar Suman , Autreto Pedro A S , Tiwary Chandra Sekhar 
Published: November 2023

Abstract
Silicon dioxide’s potential for having magnetic properties is fascinating, as combining its electronic capabilities with magnetic response seems promising for spintronics. In this work, the mechanisms that drive the change from diamagnetic behavior in pure silicates like SiO2 to paramagnetic behavior in transition metal-doped silicates like Rhodonite silicate (CaMn3Mn(Si5O15)) are explored. This naturally occurring Rhodonite (R)-silicate was thinned down while retaining its magnetic properties by liquid-phase scalable exfoliation. Exfoliating R-silicate into the two-dimensional (2D) structure by LPE increases magnetic coercivity, and the internal resistance to demagnetization (ΔHc) up to ∼23.95 Oe compared to 7.08 Oe for its bulk phase. DFT spin-polarized calculations corroborate those findings and explain that the origin of the magnetic moment comes mainly from the Mn in the doped 2D silicate due to the asymmetrical components of the Mn d and Si p states in the valence band. This result is further illustrated by the spin component differential charge densities showing that Mn and Si atoms display a residual up spin charge. Rhodonite’s unusual magnetic behavior has considerable potential for spintronics, data storage, and sensing technologies. Understanding the complex relationships between the structural, magnetic, and electronic properties of silicates is essential for developing new materials and composites as well as for driving future research.
MXene Fe2C as a promising candidate for the 2D XY ferromagnet
Authors: Agapov E M , Kruglov I A , Katanin A A 
Published: November 2023

Abstract
Monolayer Fe2C is expected to possess strong electronic correlations, which can significantly contribute to electronic and magnetic properties. In this study we consider electronic and magnetic properties of MXene Fe2C within the DFT+DMFT approach. We establish the existence of local magnetic moments

μ

l
o
c

=
3.3

μ
B

in this compound, characterized by sufficiently long lifetime of

τ
∼
350

fs. We also calculate exchange interaction parameters accounting for electronic correlations using the recently developed approach for paramagnetic phase. At low temperatures, we obtain the strongest exchange interaction 11 meV between next nearest neighboring Fe atoms, located above (or below) the carbon plane, and the subleading interaction 6 meV between the next to next nearest neighboring atoms, located across the carbon plane. The resulting dependence of the Berzinskii–Kosterlitz–Thouless (BKT) and Curie temperatures on magnetic anisotropy is obtained. The BKT temperature for the pristine Fe2C is

T

B
K
T

≃
300

K, which makes this compound a good candidate for the two-dimensional ferromagnet with XY anisotropy.
Performance assessment of surface modified natural fibre using NaOH in composite concrete
Authors: Priya C , Sudalaimani K 
Published: November 2023

Abstract
Abaca fiber degradation in concrete owing to its alkaline nature decreases the strength of concrete. This research focuses on overcoming the degradation by alkaline treatment with sodium hydroxide (NaOH) to improve fiber performance. This study was completed with the extraction process of fiber, mechanical properties, micro-structural analysis of composite fiber concrete for both M30 and M40 grades, and durability performance if the fiber content, aspect ratio of fiber and molarities of Sodium Hydroxide were optimized using splitting tensile strength of the concrete matrix and it was found that the optimum percentage of fiber content was 1% at 12% alkali treatment. The composite concrete has achieved an increase of 2700 to 3100 kg m−2 in split tensile strength with treated abaca fibers compared to untreated fiber concrete. In addition, treated abaca fiber concrete provides better performance in mechanical and durability studies. The binding nature of fiber concrete is better than that of conventional concrete, which is evidenced in microstructural analysis. This study ultimately concluded that the treated abaca fiber composite concrete is a better alternative to commercially available untreated abaca fibers and other natural fibers.