bluuebunny/crossref_metadata_2025_split huggingface dataset:
Impact of Lifestyle Factors on the development and severity of Acne Vulgaris: a cross sectional study
Authors: Seetan Khaled , Kiwan Bashar , Kasasbeh Dana , Ayesh Monther , Al-zoubi Orjwan , Al-sarhan Bashar , Al-majali Hamzeh 
Published: November 2023

Abstract
Introduction:
Acne vulgaris is a common skin disease that affects a significant portion of the population, especially adolescents and young adults. While various factors contribute to the development of acne, lifestyle factors such as diet, sleep patterns, stress levels, and personal hygiene practices may play a significant role. This study aims to investigate the impact of lifestyle factors on the development and severity of acne vulgaris.
Methods:
The survey team collected data on demographics and lifestyle from the individuals with acne vulgaris who attended dermatology clinics at tertiary hospital. Data on demographics, lifestyle factors, and acne severity were collected and analyzed data using descriptive and inferential statistics. A logistic regression analysis was done to identify predictors of acne severity.
Results:
The study examined the factors affecting acne severity in 423 participants with a mean age of 20.2 years. The results showed that younger age (aOR = 1.41), female gender (aOR = 2.56), higher BMI (aOR = 0.63 and 0.85 for BMI < 18.5 and 18.5–23), smoking (aOR = 2.61), family history of acne (aOR = 2.67), low intake of fruits/vegetables (aOR = 0.82 and 0.61 for consumption a few times a week and nearly every day) and dairy products (aOR = 0.86 for consumption a few times a week), high intake of fast food/fatty food (aOR = 1.61) and sweets/chocolate (aOR = 1.43), low physical activity (aOR = 0.75 for exercise a few times a week), short sleep duration (aOR = 1.15), and significant stress (aOR = 1.52) were all associated with higher acne severity scores on the GEA scale.
Conclusion:
More severe forms of acne are noted among females, younger individuals, those with familial history, higher BMI, unfavorable lifestyle habits, and stress. Specifically, unhealthy dietary patterns like higher fast food and lower vegetable/fruit intake, sedentary lifestyle, short sleep duration, and psychological stress appear to be linked to more severe acne. On the other hand, frequent consumption of dairy products has a protective effect.
ChatGPT to enhance learning in dental education at a historically black medical college
Authors: Rahad Khandoker , Martin Kianna , Amugo Ihunna , Ferguson Shania , Curtis Angela , Davis Anniya , Gangula Pandu , Wang Qingguo 
Published: November 2023

Abstract

In dental education of today, the didactic curriculum primarily relies on lecture-based courses, where instructors impart knowledge through presentations and discussions. The recent rise of powerful large language model-based tools, exemplified by ChatGPT (Chat Generative Pre-Trained Transformer), poses a great challenge to traditional dental education while simultaneously offering a unique resource and approach that potentially complements today’s teaching and learning, where existing widely available learning resources have often fallen short. In this paper, we used dental course materials, syllabi, and textbooks adopted currently in the School of Dentistry at Meharry Medical College to assess the potential utility and effectiveness of ChatGPT in dental education. We collected the responses of the chatbot to questions as well as students' interactions with it for assessment. Our results showed that ChatGPT can assist in dental essay writing and generate relevant content for dental students, in addition to other benefits. The limitations of ChatGPT were also discussed in the paper.
Spectral Engineering For Optimal Signal Performance In The Microwave SQUID Multiplexer
Authors: Salum J.M. , Redondo M.E. García , Ferreyro L.P. , Bonilla-Neira J. , Müller N. , Geria J.M. , Bonaparte J. , Muscheid T. , Gartmann R. , Fuster A. , Almela A. , Hampel M.R. , Ardila-Perez L.E. , Sander O. , Kempf S. , Platino M. , Weber M. , Etchegoyen A. 
Published: November 2023

Abstract
We describe a technique to optimize the dynamic performance of Microwave SQUID Multiplexer (μMUX) based systems. These systems proved to be adequate for reading out multiple cryogenic detectors simultaneously. However, the requirement for denser detector arrays to increase the sensitivity of scientific experiments makes its design a challenge. By modifying the readout power per channel, there is a trade-off between decreasing the Signal to Noise Ratio (SNR) and boosting the nonlinearities of the active devices. The latter is characterized by the Spurious Free Dynamic Range (SFDR) parameter and manifests as an increment in the intermodulation products and harmonics power. We estimate the optimal spectral location of the SQUID signal containing the detector information for different channels. Through this, what we refer to as Spectral Engineering, is possible to overcome the trade-off. By this technique, it is possible to minimize the SNR degradation of all the detector signals while maximizing their SFDR.
Study on the Design of Thermal Vibration Integrated Reliability Enhancement test Profile based on Multi-stress Failure Excitation Simulation
Authors: Xue Xiao-Feng , XU Guang-Duo , Feng Yun-Wen , Liu Jia-Qi , Yang Rong-Ji , Qin Qiang 
Published: November 2023

Abstract

The current reliability enhanced test profiles are inefficient and costly, an integrated temperature and vibration reliability enhancement test profile design method based on multi-stress failure excitation simulation (MSS-RET) for typical ballistic devices is presented in this paper. First, the fault logic analysis is conducted by combining the product fault tree and product structural characteristics, and establishment of a integrated test profile design framework, to improve the determination of profile elements of the guidelines. using multi-stress finite element deterministic analysis joint failure physical model of the failure prediction method, obtain a vibration termination stress valuation, starting stress, and other profile elements, achieved the optimization of the test accuracy; Combined with relevant standards, clarify the temperature stabilization time. Through the principle of thermal stress generation, combined with finite element simulation data analysis, specify the vibration excitation loading time, optimize fault excitation intensity, improve the low efficiency and high cost of the reinforcement test. The MSS-RET is validated by taking the design of a comprehensive temperature and vibration test profile of a fuze detection module as an example, the results shows that the obtained test profile can reduce the test error by up to 44% compared with the traditional method.
Sustainable Production of WMA with Pine Gum Wax Modification: Physical and Rheological Evaluation
Authors: GÖKALP İslam , YANİ Ramazan 
Published: November 2023

Abstract
Warm mix asphalt (WMA) produced with (S®), which is a common organic additives, (S®-WMA) shows an over-rising softening point value and a decrease in stripping resistance. These two shown behavior of S®-WMA are seen some problems that need to be solved. Because they adversely affect the structural performance of the pavement and therefore, this study is established to evaluate the possible solutions to these two problems by one more modification processes. It was investigated in this study whether modifying S®-WMA by using pine gum wax (PGW), which is a product that has not been investigated before, be a solution to the aforementioned problem. In this context, WMA was produced with S® at 1%, 2% and 3% (by bitumen mass) in 1% increments. Since PGW was not previously used as an additive to modify S®-WMA, it was added within a limit as 1% (by mass of bitumen). Physical and rheological standard tests were performed on each sample in order to demonstrate the variation in the properties of the produced S®-WMA with 1% PGW compared to S®-WMA. The results showed that the addition of 1% PGW to S®-WMA caused significant reduction in the softening point and an improvement in stripping resistance compared to S®-WMA. Thus, it shows that the use of PGW can be a potential solution for the two mentioned problems. It can also be emphasized that S®-WMA sample can be an efficient, economical and environmentally friendly solution by modifying it with PGW without compromising its properties. However, more in-depth research is required due to the use of a limited PGW contribution rate.
ZIC1 is a biomarker related to prognosis and immunity in sarcoma
Authors: Wang Ruisi , Ma Likun 
Published: November 2023

Abstract
The study aimed to determine whether ZIC1 was associated with prognosis and immune infiltration in sarcoma and provided important molecular basis in order to early non-invasive diagnosis and immunotherapy of sarcoma. Using The Cancer Genome Atlas database (TCGA) and ImmPort database, we extracted messenger RNA (mRNA) data of sarcoma and immune-related genes, then we used “DESeq2” package, “survival” package, and Venn overlap analysis to obtain the differentially expressed mRNA (DEmRNA) associated with prognosis and immunity of sarcoma patients. “pROC” package was used to analyze receiver operating characteristics (ROC) of target gene. We used two-class logistics model to identify clinicopathological parameters that correlated with target gene expression. In order to determine the effects of target gene expression and clinicopathological parameters on survival, univariate and multivariate cox regression analyses were performed. We analyzed the related functions and signaling pathways of target gene by enrichment analysis. Finally, the correlation between target gene and tumor immune infiltrating was explored by ssGSEA and spearman correlation analysis. Results showed that ZIC1 was a target gene associated with immunity and prognosis in sarcoma patients. sarcoma patients with higher ZIC1 expression had poor outcomes. In terms of ROC, ZIC1 had an area under the curve (AUC) of 0.938. ZIC1 was associated with margin stasis, OS event, DSS event and PFI event of sarcoma patients, and served as an independent predictor of overall survival in sarcoma patients. Functional enrichment analysis revealed ZIC1 was obviously enriched in pathways connected with carcinogenesis and immunosuppression. The expression of ZIC1 was significantly associated with tumor immune cells and immune checkpoints according to ssGSEA and spearman correlation analysis. To conclude, our study suggested that ZIC1 was associated with tumor immunity, and might be a biomarker associated with the diagnosis and prognosis of sarcoma patients, and a potential target of sarcoma immunotherapy.
Application of Machine Learning and Inscriptions in Solid Waste Collection and Disposal: A Case Study of University of Ibadan
Authors: Folarin Oluwatimilehin , Achi Chibueze Godwin 
Published: November 2023

Abstract

The University of Ibadan, with approximately 26,000 students, has been struggling to maintain a clean and healthy environment. To address this issue, this project was undertaken to develop a "triplet waste bin" model. The first bin, designed to collect plastic bottles using computer vision, while the second and third bins are for collecting biodegradable and non-biodegradable waste, respectively, with labels. For this study, one thousand samples of plastic bottles were collected to train a Machine Learning model called YoloV5. These samples were then used to train the model, with 20% of the dataset reserved for validation. Furthermore, images of the six most common biodegradable wastes and non-biodegradable wastes were used for making unique inscription design for biodegradable and non-biodegradable waste bins respectively. The Machine Learning model achieved an accuracy of 99.5%, implying that to a very considerable extent, the model can detect plastic bottles accurately. With this capability, the collection of plastic bottles can be improved, leading to increased recycling efforts within the University of Ibadan. Furthermore, the use of inscriptions on the bins for biodegradable and non-biodegradable waste will encourage proper waste disposal and discourage mixing of different types of waste. This, in turn, will contribute to a cleaner and healthier environment. Overall, this project provides a sustainable solution for effective waste management and recycling at the University of Ibadan. Furthermore, it has the potential to be expanded and implemented in other locations beyond the university. The ultimate goal is to create a clean and healthy environment for everyone.
Development of Innovative K-Means Clustering Application for College Entrepreneurship Education
Authors: Zhai Wenqiu 
Published: November 2023

Abstract
The traditional approach to talent development in education and workforce preparation is no longer sufficient to meet the dynamic demands of today's society and economic landscape. Modern policies aimed at promoting innovation-driven development require individuals to exhibit significant ingenuity and initiative. A growing concern shared by all sectors of society revolves around the status of student innovation and entrepreneurship (IAE) education, particularly within the context of the workplace. The unceasing pressures of economic growth have laid bare the inadequacies of the conventional talent cultivation model. It is now evident that relying solely on traditional educational methods cannot adequately equip students with the skills and mindset necessary to excel in an economy driven by innovation. In China, the domain of IAE education within universities is still in its early stages, but it is steadily advancing in both research and implementation. The recognition of the urgent need to adapt education to the demands of the 21st-century economy has sparked a surge in efforts to enhance IAE curricula. A noteworthy step in this direction is the innovative utilization of K-Means clustering (KMC) in college entrepreneurship instruction. This approach provides distinct advantages by clarifying the terminology associated with the evolving field of entrepreneurship and educational theory. It enables a deeper comprehension of concepts like entrepreneurship and the pursuit of change, which are essential in nurturing innovative mindsets and initiatives among students.
Linc20486 promotes BmCPV replication through inhibiting the transcription of AGO2 and Dicer
Authors: Chengyue Wu , Yeping Chen , Hao Li , Ping Wu , Heying Qian , Xijie Guo , Zhendong Zhang , Wang Mengdong , Tang Weiming 
Published: November 2023

Abstract
The silkworm is indeed an important economic insect, not only for its silk production but also as a model organism in scientific research. However, silkworm farming is susceptible to various factors, with silkworm viruses posing the most serious threat to the sericulture industry. The Bombyx mori cytoplasmic polyhedrosis virus (BmCPV), a member of the Reoviridae family and the Cytoplasmic polyhedrosis virus genus, is a major pathogen in silkworm production. BmCPV infection primarily results in midgut sepsis in silkworms, spreads rapidly, and can cause substantial economic losses to sericulture production. Currently, there are no effective methods for preventing and treating BmCPV virus disease.
Long non-coding RNA (lncRNA) is a type of RNA molecule with transcripts exceeding 200 nt, which plays an important role in the interaction between pathogens and host cells. Research has identified and analyzed the expression of lncRNAs through high-throughput technology and found that BmCPV infection significantly upregulates the expression of Linc20486. This suggests that Linc20486 may be involved in regulating virus replication. Exactly as predicted, knocking down Linc20486 in cells dramatically inhibits BmCPV replication, while overexpression significantly promotes virus replication.
To investigate how Linc20486affects the virus replication, effects of Linc20486on autophagy, innate immunity, and RNAi related pathways were screened. The results showed that Linc20486significantly affects the expression of RNAi pathway related genes such as Dicer and AGO2. This could potentially open new avenues for understanding and combating BmCPV infections in silkworms.
Experimental Investigation of an Incremental Contact Model for Hyperelastic Solids Using In-Situ Optical Interferometric Technique
Authors: Jiang Chunyun , Zheng Yanbin 
Published: November 2023

Abstract

The hyperelastic materials would contribute to the intricacies of rough surface contact, primarily due to the heightened nonlinearity caused by stress concentration. In our previous research, an incremental contact model tailored for hyperelastic materials is proposed and validated by finite element (FEM) simulations. From an experimental perspective, this study employs an in-situ optical interferometric technique to precisely document the actual contact zone between hyperelastic solids and quartz glass. Simultaneously, the contact force is meticulously recorded in sync by a force sensor positioned beneath the hyperelastic samples. Comparing with the predictions of incremental contact model for hyperelastic materials, a significant agreement becomes evident, almost in a range of nearly complete contact. Its significance extends to practical domains such as sealing mechanisms, leakage prevention, and structural integrity, offering valuable insights for these applications.
The effect and comfortable after extended depth of focus, multifocal and monofocal intraocular lenses implantation
Authors: Wang Junhui , Luo Jiawei , Yang Wenyu , Ren Ruoxin , Xie Yi , Li Jiaxin , Guan Huaijin , Ji Min 
Published: November 2023

Abstract

Background: Premium intraocular lens (IOL) can provide a fixed distance of near vision, which may be affected for patients who prefer different near distances. Thus, this study evaluate the effects and comfortable after implantation of extended depth of focus (EDOF), multifocal (Multi) and monofocal (Mono) intraocular lenses (IOLs).
Methods: Seventy eligibleparticipants were implanted with their preferred IOL and completed the relevant follow-up.Assessments focused on uncorrected distance, intermediate, and near visual acuity (UCDVA, UCIVA, and UCNVA, respectively), best corrected distance visual acuity (BCDVA), the fluctuations of comfortable near distance, the ability to see at comfortable or standard near distance and visual comfort during the 3-month postoperative follow-up.
Results: The EDOF and Multi groups were followed up for 3 months and showed noninferiority to the Mono group in the UCDVA (P > 0.05) and BCDVA but superiority in the UCNVA (P < 0.001). The UCIVA was best in the EDOF group, with comparable vision in the Multi and Mono groups. The comfortable near distance in the three groups was nonsharp between the pre- and postoperative periods. The comfortable near-distance visual acuity (CNDVA) was lower than the UCNVA in the three groups, particularly for the EDOF and Multi recipients (P < 0.05). The comfortable near distance effectively improved patients’ near visual comfort and visual clarity, except for one patient in the Multi group who complained of severe fatigue and was unable to tolerate the experience at month 3.
Conclusion: The EDOF and Multi IOLs achieved excellent visual quality and superior UCNVA versus the Mono IOL, but the CDNVA was significantly inferior to the UCNVA. Patients' near visual experience can be effectively increased at their comfortable near distances.
Microcalorimeter Absorber Optimization for ATHENA and LEM
Authors: Wassell Edward , Adams Joseph , Bandler Simon , Chervenak James , Cumbee Renata , Finkbeiner Fred , Fuhrman Joshua , Hull Samuel , Kelley Richard , Kilbourne Caroline , Mateo Jennette , Muramatsu Haruka , Porter Frederick , Rani Asha , Sakai Kazuhiro , Smith Stephen , Wakeham Nicholas , Yoon Sang 
Published: November 2023

Abstract

High quantum efficiency (QE) x-ray absorbers are needed for future x-ray astrophysics telescopes. The Advanced Telescope for High ENergy Astrophysics (ATHENA) mission requirements for the X-ray Integral Field Unit (X-IFU) instrument dictate, at their most stringent, that the absorber achieve vertical QE > 90.6% at 7 keV and low total heat capacity, 0.731 pJ/K. The absorber we have designed is 313 µm square composed of 1.05 µm Au and 5.51 µm electroplated Bi films [1]. Overhanging the TES, the absorber is mechanically supported by 6 small legs whose 5 µm diameter is tuned to the target thermal conductance for the device. Further requirements for the absorber for X-IFU include a > 40% reflectance at wavelengths from 1–20 µm to reduce shot noise from infrared radiation from higher temperature stages in the cryostat. We meet this requirement by capping our absorbers with an evaporated Ti/Au thin film. Additionally, narrow gaps between absorbers are required for high fill fraction, as well as low levels of fine particulate remaining on the substrate and zero shorts between absorbers that may cause thermal crosstalk. The Light Element Mapper (LEM) is an X-ray probe concept optimized to explore the soft X-ray emission from 0.2–2.0 keV. These pixels for LEM require high residual resistance ratio (RRR) thin 0.5 µm Au absorbers to thermalize uniformly and narrow < 2 µm gaps between pixels for high areal fill fraction. This paper reports upon technology developments required to successfully yield arrays of pixels for both mission concepts and presents first testing results of devices with these new absorber recipes.
Heterojunction Active Layer MAPbI3 /CsPbI3 Design for High-Performance Perovskite Solar Cells: A Computational Analysis Achieving 20.5% Efficiency
Authors: Noori Darko A. 
Published: November 2023

Abstract

This simulation study employed three distinct perovskite solar cell (PCS) structures: double electron transport layer (DETL) composed of (10–50 nm) TiO2/ (50 nm) ZnO, double hole transport layer (DHTL) incorporated of (20–100 nm) MoOx/ (200 nm) Spiro-OMeTAD, and double active layer (DAL) consisted of (300 nm) MAPbI3/ (50–150 nm) CsPbI3 based PSCs separately. These configurations aimed to increase the charge carrier population and enhance fast electron and hole injection towards the electrodes in PSCs-based MAPbI3. Then, a morphological simulation study was conducted to evaluate the spatial distribution of the electron charge carrier density within the ETL, HTL, and perovskite materials. Additionally, the investigation delved into charge carrier density, charge carrier generation, and recombination within the thin-film materials, and compared the performance of single and doubling layers of PSCs. Notably, the simulation results demonstrated a remarkable power conversion efficiency (PCE) of 20.52% for the heterojunction active layers structure, surpassing the PCE of 19.8% and 18.5% were achieved for the DHTL and DETL configuration, respectively. Moreover, the PCE of the cell enhanced by 29% with the DAL (200 nm MAPbI3/150 nm CsPbI3) structure compared to the reference cell. This study provides meaningful information for advancing the realm of high-efficiency planar PSCs founded on double absorber layer structure.