bluuebunny/crossref_metadata_2025_split huggingface dataset:
MODELING STABILITY OF DIFFERENTIAL-DIFFERENCE EQUATIONS WITH DELAY
Authors: Vizinska I. 
Published: September 2023

Differential-difference and differential-functional equations are mathematical models of ma\-ny applied problems in automatic control and management systems, chemical, biological, technical, economic and other processes whose evolution depends on prehistory. In the study of the problems of stability, oscillation, bifurcation, control, and stabilization of solutions of linear differential-difference equations, the location of the roots of the corresponding characteristic equations is very important. Note that there are currently no effective algorithms for finding the zeros of quasipolynomials. When studying the approximation of a system of linear differential-difference equations, it was found that the approximation of nonsymptotic roots of their quasi-polynomials can be found with the help of characteristic polynomials of the corresponding approximating systems of ordinary differential equations . This paper investigates the application of approximation schemes for differential-difference equations to construct algorithms for the approximate finding of nonsymptotic roots of quasipolynomials and their application to study the stability of solutions of systems of linear differential equations with many delays. The equivalence of the exponential stability of systems with delay and of the proposed system of ordinary differential equations is established. This allowed us to build an algorithm for studying the location of non-asymptotic roots of quasi-polynomials, which are implemented on a computer.

Computational experiments on special test examples showed the high efficiency of the proposed algorithms for studying the stability of linear differential-difference equations.
CONTINUOUS NOWHERE MONOTONIC FUNCTION DEFINED IT TERM CONTINUED A_2-FRACTIONS REPRESENTATION OF NUMBERS
Authors: Ratushniak S. 
Published: September 2023

We consider finite class of functions defined by parameters $e_0,e_1,e_2$ belonging to the set $A=\{0,1\}$. The digits of the continued fraction $A_2$-representation of the argument

$$x=\frac{1}{\alpha_1+\frac{1}{\alpha_2+_{\ddots}}}\equiv \Delta^A_{a_1...a_n...},$$
where $\alpha_n\in \{\frac{1}{2};1\}$, $a_n=2\alpha_n-1$, $n\in N$, and the values of the function are in a recursive dependence, namely:
$$f(x=\Delta^A_{a_1...a_{2n}...})=\Delta^A_{b_1b_2...b_n...},$$
\begin{equation*}
b_1=\begin{cases}
e_0 &\mbox{ if } (a_1,a_2)=(e_1,e_2),\\
1-e_0 &\mbox{ if } (a_1,a_2)\neq(e_1,e_2),
\end{cases}
\end{equation*}
\begin{equation*}
b_{k+1}=\begin{cases}
b_k &\mbox{ if } (a_{2k+1},a_{2k+2})\neq(a_{2k-1},a_{2k}),\\
1-b_k &\mbox{ if } (a_{2k+1},a_{2k+2})=(a_{2k-1},a_{2k}).
\end{cases}
\end{equation*}
In the article, we justify the well-defined of the function, continuous and nowhere monotonic function. The variational properties of the function were studied and the unbounded variation was proved.
Keanekaragaman Serangga Hama Pada Kawasan Agrowisata Universitas Muhammadiyah Luwuk Desa Lontos Kecamatan Luwuk Timur Kabupaten Banggai
Authors: Anggo Sulasmi , Muzain Dina , Karim Wahyudin Abdul , Lige Firga Nabila 
Published: September 2023

Serangga hama berperan sebagai merusak tanaman, saat ini belum ada penelitian mengenai serangga hama di kawasan agrowisata. Penelitian ini bertujuan untuk mengetahui indeks keanekaragaman jenis serangga hama yang terdapat di kawasan agrowisata Universitas Muhammadiyah Luwuk Desa Lontos Kecamatan Luwuk Timur Kabupaten Banggai. Dilaksanakan pada bulan juli tahun 2022. Metode penelitian yang digunakan metode deskriptif kuantitatif. Desain penelitian pemasangan perangkap yellow trap dan handpicking. Pemasangan perangkap yellow trap pada tanaman diserang oleh serangga hama yaitu tanaman markisa, ubi kayu, pepaya, delima, jambu biji, cabai, pisang, kangkung, tanaman hias pucuk ungu. Teknik pengambilan sampel metode random sampling. Data yang diambil adalah jenis serangga yang berpotensi sebagai hama di kawasan agrowisata. Data penunjang yang diukur adalah faktor lingkungan suhu udara, kelembapan kecepatan angin. Identifikasi sampel dilakukan di lapangan langsung dan di laboratorium pendidikan biologi, FKIP Universitas Muhammadiyah Luwuk. Hasil penelitian menunjukkan indeks keanekaragaman serangga hama H’= 1.87, dikategori sedang. Hal tersebut ekosistem dalam kestabilan agrowisata pada spesies telah mencapai klimaks lebih tinggi pada suatu komunitas, sehingga dapat ekosisstem sedang dan berpengaruh terhadap faktor lingkungan untuk mempertahankan hidupnya. Rata-rata suhu sebesar 28,6 0C, kelembapan rata-rata sebesar 75,4%, kecepatan angin 8,8 knots. Hasil yang diperoleh sebanyak 88 jumlah indiviu yang termasuk dalam 13 jenis spesies.
Influence of growth stimulants on the biometric indicators of four-year-old Khingam fir (white-bark) (<i>Abies nephrolepis</i> (Trautv.) Maxim.) seedlings
Authors: Ostroshenko V. Yu. 
Published: September 2023

Relevance. One of the main methods of reforestation is the use of growth stimulants, which are widely used in agriculture in Russia and abroad. In forestry, their use is carried out on an experimental basis. The increase in the sowing qualities of seeds, in the biometric indicators of seedlings is observed, their safety is activated. In this regard, the use of such growth stimulants as Zircon, HB-101, Root Super and Ferovit is relevant.Methods. The effect of root feeding with stimulants Zircon, HB-101, Root Super and Ferovit on the biometric parameters of four-year-old seedlings of Khingam fir (Abies nephrolepis (Trautv.) Maxim.) was studied. The experiments were carried out in the nursery of GTS — the branch of Federal Scientific Center of the East Asia Terrestrial Biodiversity FEB RAS. The growth of seedlings was studied in terms of stem height, height gain and root collar diameter.Results. It has been established that root fertilization with the stimulants Zircon and HB-101 has the greatest effect on the growth of fir seedlings. The increase in the height of seedlings is by 3.9–60.7%, in height gain — by 11.4–137.1%, as well as in the diameter of root collar — by 16.7-66.7% was noted. It was revealed that the use of the stimulator HB-101 in the solution concentration of 0,5 ml / 10 l has a more positive effect compared with the concentration of the drug solution of 0.5 ml / 5 l of water.
Ontogenesis <i>Victoria cruziana</i> A.D. Orb. in the greenhouse of the Stavropol Botanical Garden
Authors: Volkova V. V. , Shchegrinets N. V. 
Published: September 2023

Relevance. Water lilies are distributed almost throughout the globe. The largest are 2 species of tropical water lilies — Victoria amazonica (Poepp.) J. C. Sowerby and V. cruziana A.D. Orb. Their distribution range is South America. Of particular interest is Victoria cruziana, which grows in colder climatic conditions. On the territory of the Russian Federation, Victoria cruziana grows in the main in closed ground conditions. For 16 years, biological, morphological, adaptive features and seed reproduction of this species have been studied.Methods. Morphological studies were carried out, the seed productivity of Victoria cruziana in closed ground conditions was assessed, taking into account air temperature, water and lighting intensity.Results. Victoria cruziana is grown as an annual crop with a short growing season of 299.9 ± 56.3 days. The first underwater filamentous leaf appears on the 20th day after germination, and the second and third (narrow-lobed) — on the 25th. The formation of large floating leaves was noted on the 47th day, the growth of new leaves occurs every five days. The total number of leaves reaches 12 pcs. The plant enters the generative phase when the size of the leaves reaches 80–150 cm in diameter. The beginning of flowering is marked on the 120th (± 5) day, the diameter of the first flower is 20 cm (with subsequent increase). Seed collection takes place after pollination in 50 (± 2.1) days. With artificial pollination of plants, the indicators of real seed productivity of the fruit increase to 3150 seeds with a diameter of 0.5–0.6 cm, with self– pollination, 212–229 seeds with a diameter of 0.7–0.8 cm are formed.
Properties and application of betalaine dye isolated from regional beet variety
Authors: Chesnokova N. Yu. , Kuznetsova A. A. , Levochkina L. V. , Tarabaev M. A. 
Published: September 2023

Relevance. Consumers in todayʼs society are concerned about the safety of using synthetic dyes to color food. The development and use in the food industry of natural dyes compositions based on available plant materials remains relevant. The use of natural dye based on betalains — pigments of beets (Beta vulgaris) — in the production of food products, allows not only to improve the color range of products, but also to enrich them with biologically active compounds. The objects of the study are beetroot pigments betalaines, concentrated natural dye and cream «Glace» with the addition of concentrated betalain dye.Results. Depending on the experimental conditions, betalains were extracted from plant materials. The organoleptic and physico-chemical parameters of the concentrated natural dye and cream «Glasse» with its addition were studied.Results. It has been shown that the optimal conditions for isolating betalains from beets are their extraction with 95% ethanol, ultrasonic extraction at 25 ºC, and extraction with an aqueous solution at 60 ºC for 30 min. It has been determined that the most stable color of the pigment is maintained in the range of pH = 3.7–8.2. In the region of pH > 10 there is a sharp change of the color. Betalain extracts at a pH > 10 acquire a rich dark red color. It was shown that the betalain dye obtained by the concentration method is a dark red liquid, which has antiradical activity (1,49 мМ) and contains 11 mg/cm3 of betalains. The best organoleptic characteristics were found in the cream «Glasse» with the addition of 5% concentrated betalain dye.
Technology for processing blueberries into concentrated extracts
Authors: Kravchenko S. N. , Popov D. M. , Sankin A. S. , Kuznetsov N. V. 
Published: September 2023

Relevance. The production of food products using fruit and berry raw materials is one of the main directions in the creation of products with high nutritional value. The greatest prospects in this direction as ingredients are concentrated fruit and berry extracts due to the convenience of storage and the simplicity of the method of adding to products. The development of technologies for obtaining concentrated extracts of a functional orientation from fruit and berry raw materials, which ensure the safety of substances useful for the body, has recently become more and more relevant.Methods. The objects of the study were dried berries and pomace of blueberries, extracts obtained from them. As the main indicators in the objects, the content of vitamin C, bioflavonoids, tannins, organic acids, etc. was determined by generally accepted standard methods. The antioxidant activity of the extracts was determined by the kinetic method.Results. A technology for the production of extracts from fruit and berry raw materials has been developed, which ensures minimal influence of negative factors on the complex of biologically active substances of fruit and berry raw materials during processing and their high safety, which makes it possible to obtain extracts of functional orientation and high antioxidant activity.
Statistical forecast of the grain production development in Kemerovo region
Authors: Vidyakin A. V. , Lebed V. A. 
Published: September 2023

Relevance. The growth of geopolitical tensions and climate change lead to a decrease in stability in the world grain market, which ensures the relevance of further grain production growth in our country. Such a task is also set for industrial regions that have the necessary capabilities for this, which should increase the level of self-sufficiency. Despite certain successes in recent years, significant reserves remain for further growth in grain production.Methods. In the course of the study, there were used methods of comparison, economic-statistical, trend analysis of dynamic series, calculation-constructive, abstract-logical and other methods.Results. Based on the official statistics, an assessment was made of the existing patterns and trends in the dynamics of grain production, incl. on the main crops in the Kemerovo region. The influence of the main factors on the gross harvest of grain crops is determined. A forecast was made for the yield of grain crops based on a trend analysis of time series. The reserves for the growth of sown areas and the gross harvest of grain crops until 2025 were estimated.
Immunochromatographic test-system for express diagnostics of rabies
Authors: Galeeva A. G. , Nasyrov Sh. M. , Kashevarov G. S. , Efimova M. A. , Aleeva Z. Z. , Arutyunyan G. S. , Yarullina G. M. , Akhmadeev R. M. , Salnikov V. V. 
Published: September 2023

Relevance. Rabies is included in the group of transmissible viral zooanthroponoses that globally affect public health and the public economy. In Russian Federation, according to the State Standard 26075-2013, the method of virus isolation is a priority for the diagnosis of rabies, followed by detection by the method of fluorescent antibodies (MFA), however, the call of the World Health Organization to abandon research using animals makes it relevant to further develop and improve diagnostic methods in vitro.The purpose of the study. Designing a test system based on immunochromatographic analysis (IHA) for rapid diagnosis of rabies.Methods. Colloidal gold nanoparticles (CGN) with an optimal diameter (25–30 nm) were synthesized by citrate reduction of chloroauric acid and morphometrically characterized by the results of transmission electron microscopy. The conjugation of CGN with anti-rabies antibodies was carried out by non-covalent cross-linking, as a result of which stable conjugates were obtained with an immobilization coefficient of 91.8 ± 1.7%.Results. The classical scheme of direct (sandwich) was used IHA, in which the liquid phase (a sample containing the desired antigen) binds to labeled specific antibodies and, during migration through the solid phase, forms a colored complex with applied specific antibodies in the test zone («sandwich» NCHKZ-antibody — antigen — antibody). ICA was performed with positive, negative and heterologous antigens. The results of the study of samples by ICA were in direct correlation with the results of enzyme-linked immunosorbent assay (ELISA) and MFA and demonstrated 100% specificity. The presented data confirm the functionality of ICA for the detection of rabies virus antigen in pathological material.
The effect of microbiological and mineral fertilizers on the productivity of fodder crop rotation and the fertility of sod-podzolic soil
Authors: Tiranov A. B. , Grigoriev A. V. 
Published: September 2023

Relevance. For the first time, new biofertilizers Azotovite and Phosphatovite in combination with mineral and organic fertilizers were studied on sod-podzolic soil (83% of the arable area) in the conditions of the Novgorod region in the fodder crop rotation. The study of the influence of the methods of using microbiological fertilizers together with mineral and organic fertilizers in the developed crop rotation is relevant.Methods. Studies for 2019–2022 in the fodder crop rotation according to the 2 × 4 scheme were carried out on sod-podzolic soil underlain by clays. We studied three methods of using Azotovite (A) and Phosphatovite (F) — (factor B) on two backgrounds of complete mineral fertilizer (factor A), affecting the yield and nutritional value of crops in crop rotation.Results. Application in technological operations (twice) azotovite and phosphatovite (pickling of seed material at 2 l/t and non-root spraying in the phases of plant formation at a height of up to 30 cm, 1 l/ha of each preparation) together with mineral fertilizers for the estimated yield ensured the productivity of the phytomass of the vico-oat mixture of 35 t/ha with high nutritional value: collection of dry matter (SV) — 11.0 t/ha, digestible protein — 0.83 t/ha, exchange energy — 32.0 GJ/ha. The use of this technology provided for the rotation of crop rotation high nutritional value of feed from 1 ha of digestible protein — 0.45 t, exchange energy — 33.0 GJ, SV — 5.3 t with a low energy intensity of production thousand tons of units 2.6 GJ and an increase in the energy potential of the soil for crop rotation by more than 35 GJ/ha.
Response of soybean varieties to weather conditions in Primorsky Krai
Authors: Lukyanchuk L. M. , Butovets E. S. 
Published: September 2023

Relevance. The soybean breeding process, focused on increasing the level of qualitative and reproductive indicators of the culture under the means of hybridization, further evaluation of the obtained genotypes and selection of promising samples, has an extremely relevant research direction.Results. The research determined how weather and climatic factors influenced the yield, protein content in seeds, and resistance to fungal diseases of promising soybean varieties under the conditions of Primorsky Krai. High-yielding accessions (3.08–3.59 t/ha) from combinations «Arisa × Taifun» and «NIISKH 3 × Taifun» were selected. A high TKW was characteristic of hybrid combination «Primorskaya 13 × Kofu» (207 g). During the growing season of the crop, there were conditions of insufficient (2021) and excessive (2022) moisture, which had a different effect on the yield level of soybean varieties on average according to experience (17.1 c/ha and 34.0 c/ha, respectively). The conditions of 2022 were optimal for the ontogeny of soybean. Varieties Primorskaya 1690, Primorskaya 1693, and Primorskaya 1696 had the highest yield in 2022 exceeding the standard by 38.0–54.7%. The highest yield was achieved under the conditions of short-term heavy precipitation in combination with high temperature during the growing period. Soybean seeds had a higher protein content after heavy precipitation with short periods of moisture excess from July to August. Under more favorable conditions for the development of fungal pathogens (in 2022), the degree of damage to soybean plants significantly increased (by 16.0%). The studied varieties were resistant to downy mildew and Cercospora.leaf spot (the degree of damage was up to 25.0%).
Parathyroid hormone therapy improves MRSA-infected fracture healing in a murine diabetic model
Authors: Kwon Hyuk-Kwon , Cahill Sean V. , Yu Kristin E. , Alder Kareme D. , Dussik Christopher M. , Jeong Jain , Back Jung Ho , Lee Francis Y. 
Published: September 2023

IntroductionDiabetes mellitus (DM) impairs fracture healing and is associated with susceptibility to infection, which further inhibits fracture healing. While intermittent parathyroid hormone (1-34) (iPTH) effectively improves fracture healing, it is unknown whether infection-associated impaired fracture healing can be rescued with PTH (teriparatide).MethodsA chronic diet-induced type 2 diabetic mouse model was used to yield mice with decreased glucose tolerance and increased blood glucose levels compared to lean-fed controls. Methicillin-resistant Staphylococcus aureus (MRSA) was inoculated in a surgical tibia fracture model to simulate infected fracture, after which mice were treated with a combination of antibiotics and adjunctive teriparatide treatment. Fracture healing was assessed by Radiographic Union Scale in Tibial Fractures (RUST), micro-computed tomography (μCT), biomechanical testing, and histology.ResultsRUST score was significantly poorer in diabetic mice compared to their lean nondiabetic counterparts. There were concomitant reductions in micro-computed tomography (μCT) parameters of callus architecture including bone volume/total volume, trabecular thickness, and total mineral density in type 2 diabetes mellitus (T2DM) mice. Biomechanicaltesting of fractured femora demonstrated diminished torsional rigidity, stiffness, and toughness to max torque. Adjuvant teriparatide treatment with systemic antibiotic therapy improved numerous parameters of bone microarchitecture bone volume, increased connectivity density, and increased trabecular number in both the lean and T2DM group. Despite the observation that poor fracture healing in T2DM mice was further impaired by MRSA infection, adjuvant iPTH treatment significantly improved fracture healing compared to antibiotic treatment alone in infected T2DM fractures. DiscussionOur results suggest that teriparatide may constitute a viable adjuvant therapeutic agent to improve bony union and bone microarchitecture to prevent the development of septic nonunion under diabetic conditions.
Case report: Serious unexpected vascular events in two patients with lymphocytic variant hypereosinophilic syndrome
Authors: Torcida Nathan , Casalino Giulia , Bondue Antoine , Jodaitis Lise , Vanden Eynden Frederic , Roufosse Florence 
Published: September 2023

BackgroundLymphocytic-variant hypereosinophilic syndrome (L-HES) is a form of reactive hypereosinophilia, most commonly associated with interleukin-5 over-production by clonal, most commonly CD3−CD4+CD2hiCD5hiCD45RO+ T-cells. Patients often present with predominant cutaneous and soft-tissue manifestations, while cardiovascular involvement is uncommon.MethodsWe reviewed the medical files of two L-HES patients followed in our center who developed serious vascular complications and performed a literature review for similar cases.ResultsPatient 1, a 52-year-old female, presented with an ischemic stroke secondary to left middle cerebral artery dissection after 10 years of indolent L-HES. Blood eosinophilia was controlled with oral corticosteroids (OCS), but OCS-tapering attempts with hydroxyurea and pegylated interferon failed, prompting the introduction of mepolizumab with rapid normalization. Patient 2, a 62-year-old female, had been asymptomatic for 10 years without treatment when a NSTEMI occurred, due to coronary artery occlusion secondary to a large cauliflower-aneurysm of the proximal aorta and aneurysmal dilatation of several coronary arteries, requiring semi-urgent surgical management. Aortic wall staining for eosinophil major basic protein showed eosinophils in the adventitia. Blood eosinophilia was controlled with OCS.ConclusionsPatients with apparently clinically benign L-HES may develop arterial complications, consisting in dissection and/or aneurysm dilatation of medium-to-large vessels with serious consequences. The value of performing regular vascular imaging and monitoring during follow-up has yet to be determined.