bluuebunny/crossref_metadata_2025_split huggingface dataset:
Long-term Recurrence Rates After Isolated Arthroscopic Bankart Repair in Selected Patients Without Preoperative Bone Loss Versus Open Latarjet Procedure: A Matched-Pair Analysis
Authors: Rieussec Clémentine , Cassinelli Juan Enrique , Hoffman Matias , Horteur Clément , Barth Johannes 
Published: January 2025

Background: Clinical studies have shown that the open Latarjet procedure (OLP) has lower recurrence rates than the isolated arthroscopic Bankart (IAB) procedure for recurrent anterior shoulder instability, but no long-term comparative studies exist for IAB in patients without bone loss. Purpose/Hypothesis: This study aimed to compare the outcomes of IAB in selected patients without bone loss versus OLP. The hypothesis was that OLP would be more successful in preventing recurrence, even in carefully selected patients for IAB. Study Design: Cohort study; Level of evidence 3. Methods: An overall 774 patients who underwent surgical stabilization for recurrent anterior instability between January 2007 and December 2021 were analyzed. A total of 685 shoulders were followed up (89 patients were lost of follow-up: 11,4%), including 582 OLP, 45 IAB, and 58 other techniques (Trillat procedure, Arthroscopic Latarjet procedure, and revision Eden Hybinette procedure). The patients who underwent primary IAB were matched with patients who underwent OLP in a 1:1 ratio using propensity matching, resulting in 45 patients in each group. The main objective was to identify new episodes of instability, with a recurrence rate <5% considered acceptable. Kaplan-Meier analysis was used to evaluate patient survivorship, and logistic regression was performed to consider potential factors affecting recurrence rates. Data were collected on return-to-sport rate, Walch and Duplay score, visual analog scale score, and external rotation. Results: The mean follow-up was 9 years and 3 months. A new episode of instability occurred in 2% of the OLP group and 20% of the IAB group ( P = .04; odds ratio, 11; 95% CI, 1.91-63.4, Miettinen method). Regarding the rest of our analyses, there was no significant difference. Patients maintained good external rotation with low pain: 68° in the OLP group as compared with 72° in the IAB group ( P = .325), with 1.2 out of 10 on the visual analog scale in the OLP group versus 1.5 in the IAB group ( P = .433), respectively. Walch and Duplay score reached 79.9 in the OLP group and 78.9 in the IAB group ( P = .496), and 89% of the OLP group returned to its previous sport level as compared with 73% of the IAB group ( P = .104). Conclusion: Patients who underwent an OLP had better long-term survivorship without recurrence when compared with those who underwent an IAB, even without bone loss. The odds of experiencing a new episode of instability recurrence was 11 times higher for patients who underwent IAB, with a mean follow-up of 9 years and 3 months.
Promoting Evidence-Based Tobacco Cessation Treatment in Community Mental Health Clinics: Results of a Pilot Implementation Study: Promouvoir le traitement de sevrage tabagique fondé sur des données probantes dans les cliniques communautaires de santé mentale : résultats d’une étude pilote de mise en œuvre
Authors: Dickerson Faith , Fink Tyler , Goldsholl Stacy , Dalcin Arlene , Eidman Benjamin , Yuan Christina T. , Gennusa Joseph V. , Cather Corinne , Evins A. Eden , Wang Nae-Yuh , McGinty Emma M. , Daumit Gail L. 
Published: January 2025

Objective Tobacco smoking is the leading cause of preventable death among individuals with serious mental illness (SMI) but few persons with SMI are offered smoking cessation treatment. The purpose of this study was to pilot-test a multicomponent intervention to increase the delivery of evidence-based smoking cessation treatment in community mental health clinics (CMHCs). Method This study was carried out at five CMHCs in Maryland involving clinicians who participated in training in smoking cessation. Other implementation activities included the provision of a treatment protocol, coaching, expert consultation, and organizational strategy meetings. The primary outcome was a change in clinicians’ knowledge and self-efficacy about smoking cessation. Secondary outcomes included documentation of evidence-based smoking cessation practices including assessment of smoking status and readiness to quit, and provision of smoking cessation treatment over the course of the 12-month intervention period. Results A total of 91 clinicians participated in the study. Data were available on 6,011 clients. Clinicians’ scores on the knowledge and self-efficacy measures increased modestly over the course of the implementation period. Overall, 57% of clients had their smoking status assessed; 81% of current smokers were evaluated about their willingness to quit; 82% of those willing to quit within 90 days received behavioral counseling, and 36% were prescribed or given smoking cessation pharmacotherapy. Clinicians rated the smoking cessation program highly in terms of acceptability, appropriateness, and feasibility. Conclusions Clinicians at CMHCs were engaged by and participated in training and implementation activities around smoking cessation practices which they then delivered to a substantial portion of clients in their care. The results of this study provide important data for the future planning of testing implementation strategies to scale up tobacco cessation treatment in this population in outpatient mental health settings.
Research on ring artifact reduction method for CT images of nuclear graphite components
Authors: Zeng Tianchen , Fu Jintao , Cong Peng , Liu Ximing , Xu Guangduo , Sun Yuewen 
Published: January 2025

Background The supporting structure of high-temperature gas-cooled reactors (HTGR) comprises over 3000 carbon/graphite components, necessitating computed tomography (CT) non-destructive testing before operational deployment as per reactor technical specifications. However, CT images are frequently marred by severe ring artifacts due to the response non-uniformity and non-linearity of detector units, which diminishes the ability to detect defects effectively. Methods To address this issue, we propose a physics-based ring artifacts reduction method for CT that employs pixel response correction. This method physically accounts for the cause of ring artifacts and leverages the prior knowledge of the detected object to enhance the accuracy of the detection process. Results Our proposed method achieved a notable reduction in ring artifacts, as evidenced by a 37.7% decrease in ring total variation (RTV) values compared to the originals, significantly enhancing image quality. It also surpassed traditional and machine learning methods in artifact reduction while maintaining image details. The lower RTV scores confirm our method's superior effectiveness in minimizing ring artifacts. Conclusion We believe that our research contributes to the enhancement of defect inspection performance in detection systems, which is crucial for ensuring the safety of reactors. The proposed method's effectiveness in mitigating ring artifacts while maintaining image quality highlights its potential impact on the reliability of non-destructive testing in the context of HTGR components.
Technological advancements in right heart acoustic angiography for predicting patent foramen ovale and its correlation with AIS: A retrospective study
Authors: Qin Haidong , Qin Xipiao , Jiang Xianzhi 
Published: January 2025

Background Acute ischemic stroke (AIS) is a leading cause of disability and mortality worldwide, often resulting from embolic events. Patent foramen ovale (PFO), a common congenital heart defect, has been identified as a potential source of emboli in AIS patients, especially in cases of cryptogenic stroke where no other etiology is found. Objective This study aimed to investigate the relationship between AIS and PFO, and to explore the diagnostic value of right heart acoustic angiography for PFO. Methods A study included 148 AIS and 111 non-AIS patients with suspected PFO, using transesophageal echocardiography (TEE) as the diagnostic gold standard. Sensitivity, specificity, and accuracy of right heart acoustic angiography for PFO diagnosis were evaluated. ROC and Spearman correlation analyses assessed diagnostic value and the association between AIS and PFO. Results PFO was detected in 79 AIS patients and 20 non-AIS patients, with a higher detection rate in the AIS group ( P < 0.05). Right heart acoustic angiography showed a diagnostic accuracy of 95.37% for PFO, with a sensitivity of 95.37% and a specificity of 97.78%. The AUC value of the ROC curve for right heart acoustic imaging was 0.975, indicating high diagnostic efficacy for PFO. PFO was positively correlated with AIS (r = 0.318, P < 0.001). Conclusion PFO is commonly detected in AIS patients and is positively correlated with AIS. Right heart acoustic imaging has high diagnostic efficacy for PFO and can be a valuable diagnostic tool for patients with PFO.
Paternity leave take-up in a segmented labor market: A cautionary tale of rapid policy expansion in Spain
Authors: Marinova Dani M. , León Margarita 
Published: January 2025

To evaluate the success of paternity leave as a progressive, equal-access policy instrument, it is essential to assess it against the backdrop of preexisting labor market inequalities that condition its use. We investigate the recent and rapid expansion of paternity leave entitlements in Spain where leave was extended from four to 16 weeks over the course of just three years. Analyses of an original survey administered to cohorts of fathers with leave entitlements of varying lengths show that average take-up surges but does so unevenly. As uptake rates soar among fathers in stable employment, fathers in temporary jobs, the self-employed, and those at the bottom and top of the income distribution maintain lower levels of usage. These results align with the ‘Matthew Effect' of social policy, whereby reforms disproportionately benefit well-positioned socioeconomic groups, and imply bleak prospects for the reform’s capacity to generate social change across social strata. The results thus tell a cautionary tale of the rapid expansion of paternity leave in a segmented labor market where work culture and gender norms are slower to adjust. With the enforcement of the 2019 EU Work-Life Balance Directive, other European Member States are looking to extend paternity leave swiftly, thus increasing the relevance of these results for policy considerations.
A Preliminary Study of Hearing Loss in Children With Craniosynostosis
Authors: Min Eric , Munday John , Bricker Josh , Findlen Ursula , Baylis Adriane L. , Asti Lindsey , Pearson Gregory 
Published: January 2025

To describe the frequency and types of hearing loss in children with syndromic and non-syndromic craniosynostosis. Retrospective cohort study. Large tertiary pediatric hospital. Children with craniosynostosis that underwent at least one audiological evaluation between the years of 2010 and 2021 at a single institution. Hearing loss was defined as conductive or permanent (sensorineural or mixed). Of 130 total children examined, 107 (82.3%) had non-syndromic craniosynostosis and 23 (17.7%) had syndromic craniosynostosis. Within the non-syndromic cohort, 77 (72%) had normal hearing and 30 (28%) had hearing loss, of which 21/30 (70%) had conductive hearing loss and 9/30 (30%) had permanent hearing loss. Within the syndromic cohort, two (9.5%) had normal hearing and 21 (90.5%) had hearing loss, of which 16/21 (76.2%) had conductive hearing loss and 5/21 (23.8%) had permanent hearing loss. Multivariable analysis involving syndromic status, anatomical type of craniosynostosis, and medical complexity revealed that patients with syndromic craniosynostosis had higher odds for conductive and permanent hearing loss (49.80 OR, P = .002 and 34.91 OR, P < .05, respectively). Patients with unicoronal craniosynostosis and those with significant medical comorbidities had higher odds for permanent hearing loss (19.50 OR, P = .03 and 23.36 OR, P < .05, respectively). Children with craniosynostosis had high rates of hearing loss, especially those with syndromic or unicoronal craniosynostosis and those with significant medical comorbidities. Twenty-eight percent of patients with non-syndromic craniosynostosis also had hearing loss. Larger prospective studies are necessary to more precisely estimate hearing loss associated with non-syndromic craniosynostosis.
Deep Learning-Based Assessment of Lip Symmetry for Patients With Repaired Cleft Lip
Authors: Rosero Karen , Salman Ali N. , Harrison Lucas M. , Kane Alex A. , Busso Carlos , Hallac Rami R. 
Published: January 2025

Objective Post-surgical lip symmetry assessment is a key indicator of cleft repair success. Traditional methods rely on distances between anatomical landmarks, which are impractical for video analysis and overlook texture and appearance. We propose an artificial intelligence (AI) approach to automate this process, analyzing lateral lip morphology for a quantitative symmetry evaluation. Design We utilize contrastive learning to quantify lip symmetry by measuring the similarity between the representations of the sides, which is subsequently used to classify the severity of asymmetry. Our model does not require patient images for training. Instead, we introduce dissimilarities in face images from open datasets using two methods: temporal misalignment for video frames and face transformations to simulate lip asymmetry observed in the target population. The model differentiates the left and right image representations to assess asymmetry. We evaluated our model on 146 images of patients with repaired cleft lip. Results The deep learning model trained with face transformations categorized patient images into five asymmetry levels, achieving a weighted accuracy of 75% and a Pearson correlation of 0.31 with medical expert human evaluations. The model utilizing temporal misalignment achieved a weighted accuracy of 69% and a Pearson correlation of 0.27 for the same classification task. Conclusions We propose an automated approach for assessing lip asymmetry in patients with repaired cleft lip by transforming facial images of control subjects to train a deep learning model, eliminating manual anatomical landmarks. Our promising results provide a more efficient and objective tool for evaluating surgical outcomes.
Suspected Stonefish Envenomation in Reunion Island: 15 Years Later
Authors: Renson Louis , Maillet François , Bonnet Corentin 
Published: January 2025

Introduction Although marine envenomations are a reason for consultation in tropical emergency departments, stonefish stings are particularly feared. Immediate management focuses on pain control, whereas late management addresses cutaneous complications. This study presents a new series and compares the management of these patients and their outcomes at our center over the past 20 years. Methods This study presents a new series of 53 patients treated between 2016 and 2020 at the South Hospital of the University Hospital Center of Réunion following a sting attributed to the stonefish. We compared this new series with a previous series of patients treated at the same center for the same reason between 2001 and 2005. Results The series are comparable. Regarding early management, the use of regional anesthesia was more frequent (47 vs 3.5%). Half the patients received a strong opioid. Prescription of nonsteroidal anti-inflammatory drugs and corticosteroids persisted. Exposure to a heat source remained common. Prophylactic antibiotics were prescribed more frequently (64 vs 35%) and more uniformly with amoxicillin/clavulanate. Regarding late management, the average duration of hospitalization decreased (1.8 vs 2.6 d). Cutaneous complications were less frequent (9 vs 25%). No patient managed with regional anesthesia presented cutaneous complications. Conclusions The management of patients in Réunion following Scorpaenidae stings has evolved over time. Regional anesthesia has become more widespread, and the prescription of probabilistic preventive antibiotic therapy is more homogeneous. These changes are associated with a shorter hospital stay and fewer cutaneous complications.
Safety and efficacy of a modified suprachoroidal silicone tube shunt implant in primary open angle and pseudo-exfoliative glaucoma
Authors: Labauri Nikoloz , Mamageishvili Tekla , Vachiberidze Ana , Zalinian Monika , Svanadze Lika , Sabanadze Luka , Huseynov Orkhan , Sulkhanishvili Tamar , Labauri Maka , Shakarashvili Marine , Omiadze Mikheil , Solberg Yoram 
Published: January 2025

Purpose To assess the safety and efficacy of a modified suprachoroidal silicone tube (SST) shunt in patients with primary open-angle glaucoma (POAG) and pseudo-exfoliative glaucoma (PXG) in this experimental study. Methods In this single-center, retrospective longitudinal data analysis 66 eyes of 59 patients having POAG and PXG were included and treated with modified SST shunt in combination with cataract or as a stand-alone procedure. Pre- and postoperative intraocular pressure (IOP), best corrected visual acuity (BCVA), C/D ratio and ocular adverse events (AEs) were assessed in all participants. Results The average follow-up period was 18.56 ± 7.93 months. Mean baseline IOP reduced from 27.02 ± 5.43 mmHg to 13.23 ± 3.70 mmHg ( p < 0.001). Mean number of ocular hypotensive medications reduced from 3.17 ± 0.89 to 1.83 ± 1.44 ( p < 0.001). BCVA remained stable in 49 eyes (74.2%) throughout the follow-up period. Mean baseline BCVA of 0.73 ± 0.27 slightly declined to 0.68 ± 0.30 at the final follow-up ( p < 0.001). Three adverse events of special interest (AESI) were observed hypotonic maculopathy, anterior chamber inflammation with pupillary membranes, and macular edema. None of these events was related to the SST shunt. Other complications such as intra and early postoperative hyphema in 3 and tube-iris contact causing slight corectopia in 2 cases were noted. Conclusions The surgical technique and device studied in this work demonstrated a good safety profile and signal of efficacy. This device may serve as a bridge between minimally invasive glaucoma surgeries (MIGS) and conventional filtering or episcleral tube shunt surgeries. A larger scale prospective trial is planned.
Dosimetric and Radiobiological Impact of Patient Setup Errors in Intensity-modulated Radiotherapy for Esophageal Cancer
Authors: Cai Jia-Huan , Peng Xun , Lu Jia-Yang 
Published: January 2025

Purpose To evaluate the impact of patient setup errors on the dosimetry and radiobiological models of intensity-modulated radiotherapy (IMRT) for esophageal cancer. Methods and materials This retrospective study with 56 patients in thermoplastic mask (TM) and vacuum bag (VB) groups utilized real setup-error (RSE) data from cone-beam CT scans to generate simulated setup-error (SSE) data following a normal distribution. The SSE data were applied to simulate all treatment fractions per patient by shifting the plan isocenter and recalculating the dose. A simulated plan sum (SPS) was created by accumulating all simulated fraction plans. Comparisons of target dose, improved homogeneity index (iHI), conformity index (CI), tumor control probability (TCP) and normal tissue complication probability (NTCP) were conducted between SPSs and original treatment plans (OTPs). Correlations between RSE and TCP/NTCP were analyzed. Results Compared to OTPs in the TM group, the planning target volume (PTV) of SPSs showed reductions in D95%, D98%, iHI, CI and TCP by 1.2%, 2.2%, 2.3%, 7.3% and 1.2%, while D2% increased by 0.3%; D2% of clinical target volume (CTV) increased by 0.2% ( P < .05). In the VB group, D95%, D98%, iHI, CI and TCP of PTV decreased by 2.5%, 4.5%, 4.2%, 15.6% and 2.0%, with D2% increasing by 0.5%; D2% of CTV increased by 0.5% while D98% decreased by 0.2% ( P < .05). The dose of organs at risk (OARs) changed slightly in both groups. The mean and standard deviation of absolute RSE negatively correlated with the TCP of PTV, while the mean RSE positively correlated with the NTCP of lung and spinal cord. Conclusions Setup errors may reduce dose homogeneity and conformity, potentially reducing TCP of PTV and increasing NTCP, especially when mean RSE shifts the isocenter towards OARs. VB immobilization may result in relatively larger impacts of setup errors, but this needs future validation.
Evaluating neurofilament light chain serum levels as a diagnostic marker for Lyme neuroborreliosis
Authors: Hirzel Cédric , Grütter Annina , Grandgirard Denis , Hoepner Robert , Suter-Riniker Franziska , Leib Stephen L. 
Published: January 2025

Background: Serum neurofilament light chain (sNfL) is a biomarker for neuro-axonal injury. Objectives: To assess sNfL’s utility as a diagnostic marker for Lyme neuroborreliosis (LNB). Methods: We compared serum and CSF NfL levels in LNB patients and age-matched controls. Age-adjusted NfL values were used in receiver operating characteristic (ROC) analysis. Design: Retrospective cohort study. Results: Eighty-six patients (30 LNB, 29 with-, and 27 without neurological disorders) were included. Compared to individuals without neurological disease, LNB patients showed increased serum (median (interquartile range, IQR): 36.3 pg/ml (19.3–112.0) vs 20 pg/ml (12.9–37.3), p < 0.001) and CSF NfL levels (median (IQR): 1000.0 pg/ml (286.0–6471.0) vs 182 pg/ml (99.3–474.0), p < 0.001). NfL concentrations were similar in LNB and other neurological disorders. ROC analysis of age-adjusted sNfL and CSF NfL levels showed areas under the curve of 0.78 (95% confidence interval (CI): 0.66–0.89) and 0.83 (95% CI: 0.71–0.94), respectively. Conclusion: sNfL concentrations lack sufficient diagnostic capability for LNB diagnosis.
Prevalence of gastrointestinal symptoms after recovery from COVID-19: A questionnaire-based study in the Aseer region
Authors: Alzahrani Mohammed Attieh , Altalhiyyah Khalid Siraj , Albariqi Mohammed Mousa , Alkhayri Meshal Ali , Alshahrani Saad Ali , Alnasser Sultan Saad , Alshehri Nawaf Mohammed , Alqahtani Saad Haif , Alqahtani Saud Haif 
Published: January 2025

Background: The coronavirus disease 2019 (COVID-19) pandemic has affected millions of people worldwide, and although it is primarily a respiratory illness, gastrointestinal symptoms have been reported in a significant proportion of patients. Aim: Prevalence of gastrointestinal symptoms after recovery from COVID-19. Methodology: A community-based cross-sectional study was conducted in the Aseer region of Saudi Arabia. The study population included individuals aged 18 years or older with COVID-19 and living in the Aseer region. The data were collected through a pretested, structured online questionnaire preceded by consent and were used to maintain the confidentiality of the data. The questionnaire covered participants’ data, COVID-19 infection status, and gastrointestinal tract symptoms during and after recovery from the infection. Results: A total of 409 participants in the Aseer region completed the study survey. The participants’ ages ranged from 18 to more than 50 years, with a mean age of 34.5 ± 11.9 years. A total of 205 (50.1%) participants were females. A total of 263 (64.3%) of the study participants experienced gastrointestinal tract symptoms during COVID-19 infection. Additionally, 203 (49.6%) of the study participants had gastrointestinal tract symptoms after recovering from COVID-19 infection. The most commonly reported symptoms were diarrhea (13.2%), nausea (13.2%), anorexia (12.7%), abdominal pain (11%), and constipation. Male sex who suffered form severe COVID-19 infection, and gastrointestinal tract symptoms during acute infection were significantly associated with post-COVID-19 gastrointestinal tract symptoms ( p < 0.05). Conclusions: In conclusion, the current study showed that nearly two-thirds of active COVID-19 patients experienced gastrointestinal tract symptoms. Additionally, approximately half of the COVID-19 patients who recovered had gastrointestinal tract-related symptoms, but few of those patients had gastrointestinal tract-related symptoms within 1 week.