bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluación de la actividad antimicrobiana y tóxica de los extractos orgánicos de hojas de Tecoma fulva subsp. Arequipensis (cahuato)
Authors: Fernández Jorge Pascual Chávez , Lazo Virginia Ana de los Angeles Lizárraga , Cuno Surama Magdalena Quispe , De Nieto María Eleana Vargas 
Published: October 2023

Introducción: La resistencia a los antimicrobianos, conducen a la búsqueda de nuevas alternativas en los vegetales para el tratamiento de enfermedades. Los extractos del género Tecoma han sido utilizados en la medicina tradicional y académica. En el Tecoma fulva subsp. arequipensis se investigará la actividad in vitro, con la finalidad de encontrar nuevos vegetales con sustancias químicas, que tengan actividad antimicrobiana y menor toxicidad. Objetivo: Evaluar el perfil fitoquímico, antimicrobiano y tóxico de los extractos orgánicos de las hojas de T. fulva subsp. arequipensis frente a patógenos de importancia clínica.
Métodos: Incluye la recolección, secado y maceración; los extractos orgánicos crudos de diferente polaridad fueron concentrados en rotaevaporador, se realizo el análisis fitoquímico; y la actividad antimicrobiana en bacterias: S. aureus ATCC 25923, E. faecalis ATCC 29212, E. coli ATCC 25922, K. pneumoniae ATCC 700603 y P. aeruginosa ATCC 27853. Como control positivo se usó gentamicina, la actividad toxica en A. salina. Resultados: Del screening fitoquímico permitió detectar la presencia de alcaloides, saponinas, terpenos, flavonoides, sesquiterpenlactonas, quinonas y coumarinas. Las cepas que mostraron alta sensibilidad al extracto con acetato de etilo fueron: E. coli ATCC 25922, con CIM de 6,25 mg/mL; CBM de 25,0 mg/mL y diámetro de zona de inhibición de 17,00 ± 0,19 y P. aeruginosa ATCC 27853 con CIM de 6,25 mg/mL. CBM de 12,5 mg/mL y diámetro de zona de inhibición de 18,00 ± 0,19 mm. Las cepas que mostraron mediana sensibilidad fueron: S. aureus ATCC 25923 con diámetro de zona de inhibición de 21,00 ± 1,05; E. faecalis ATCC 29212 con diámetro de zona de inhibición de 19,00 ± 0,26 y K. pneumoniae ATCC 700603, con diámetro de zona de inhibición de 18,00 ± 0,23 con CIM de 12,5 mg/mL y CBM de 25,00 mg/mL. La dosis letal media (DL50) en A. salina fue de 117,41 ppm considerado moderadamente tóxico. Conclusiones: La T. fulva subsp. Arequipensis actua como producto natural bioactivo, por contener sustancias químicas que inhiben el crecimiento de microorganismos patógenos.
Uso del ultrasonido para la elección de tubo endotraqueal: serie de casos
Authors: Herrera Cristian Ivan Velasquez , Silva Fernando Aguilar , Gutierrez Adan Adonay Davila , Gavilanes Karen Estefanía Pillajo 
Published: October 2023

El tamaño apropiado del tubo endotraqueal (ETT) en adultos se determina comúnmente usando 7.0 más menos 0.5 mm para Mujeres y 8.0 más menos 0.5 mm en hombres. La determinación del tamaño del ETT basada en la medición por ecografia, del diámetro subglótico (SD), la porción más estrecha de la vía aérea superior, puede proporcionar un mejor método para un ajuste preciso. En este artículo se evaluó el uso de la ecografía para la selección correcta del tubo endotraqueal, en una serie de diez pacientes con predictores de vía aérea difícil.
Expresión CDC6 y geminina en células de cáncer cervical
Authors: Mora Wendy Aide Castro , Hernández Oscar Del Moral , Aguiar Berenice Illades , Romero Luz del Carmen Alarcón 
Published: October 2023

La proliferación celular es un proceso que estimula o limita el crecimiento, la desregulación de este proceso se asocia con el cáncer. Las proteínas como CDC6 y Geminina están implicadas en el ciclo celular, específicamente en la replicación del DNA. CDC6 es una proteína esencial en fase G1 para ensamblaje, actividad y desensamblaje de complejos proteicos en los orígenes de la replicación, mientras que Geminina es una proteína que inhibe la replicación durante la fase S/G2 mediante su interacción con Cdt1. CDC6 y Geminina se han relacionado con el estado proliferativo de la células y la sobreexpresión de estos factores de la replicación del DNA predispone a las células a la transformación maligna. El objetivo fue evaluar la expresión de CDC6 y Geminina en células de cáncer cervical con VPH 16 y 18. Los resultados muestran que las proteínas CDC6 y Geminina se sobreexpresan en líneas celulares de cáncer cervical con VPH tipo 16 y 18. Nuestros datos sugieren que los mecanismos que regulan la expresión de CDC6 y Geminina pueden estar alterados por la presencia del VPH-AR como el tipo 16 y 18 en las células de cáncer cervical.
Las residencias profesionales y su contribución a la solución de problemas en la empresa
Authors: Reséndiz Karina Berlanga , Mendoza Silvia Elena Barrios , Navarro Claudia Cruz , Zúñiga Raúl Altamirano , Calderón Javier Arturo Balderas , González Jaqueline Montserrat Gaspar 
Published: October 2023

Se describe a través de un ejemplo los beneficios que se obtienen con la vinculación escuela-empresa, al realizar actividades colaborativas y llevar a la práctica los conocimientos teóricos, los estudiantes son capaces de identificar y resolver problemas específicos del sector productivo en donde se encuentran desarrollando la residencia profesional. El ejemplo es en una empresa dedicada a la fabricación y distribución de productos de acero inoxidable, se logró la identificación y clasificación de los principales defectos que presentan las piezas analizadas, así como la determinación de las principales causas que los generan; el estudiante realizó la recopilación de información, interpretación y análisis objetivo de la información para la toma de decisiones efectivas que coadyuvarán a mejorar la calidad del producto y optimizar recursos. Esta experiencia demuestra la importancia de continuar esta estrategia de vinculación escuela-empresa para beneficio de estudiantes, mejorando con ello la calidad en la educación.
Pengaruh Kemudahan Penggunaan, Risiko, Keamanan, dan Fitur Layanan terhadap Minat Masyarakat Menggunakan Aplikasi OVO di Kota Samarinda
Authors: Zulfikar Zulfikar , Apriliyati Khofifah Tri 
Published: October 2023

AbstractThe Effect of Ease of Use, Risk, Security, and Service Features on Public Interest in Using OVO in Samarinda City. Thesis for the Department of Accounting, Finance and Banking Study Program, under the guidance of Mr. Dr. Sudarlan, SE, MT as the first supervisor and Zulfikar, S.E, M.SA (Humbis) as a second guide. This study uses quantitative methods. Data collection techniques in This study uses the technique of distributing questionnaires, observation, and literature. The sample in this study were 250 respondents. Data analysis techniques to be used used in this research are Validity Test, Reliability Test, Classical Assumption Test, Normality Test, Multicollinearity Test, Heteroscedasticity Test, Linear Regression Test Multiple, t test, f test, correlation coefficient, coefficient of determination and use IBM SPSS Version 19 software. The results of this study partially variable Ease of Use, Risk, Security, and Service Features Against Public Interest in Using OVO in Samarinda City., seen from Tcount < T table (-0483 < 1.969) and sig value of 0.629 < 0.05, partially the risk variable has a significant positive effect on Community Interest using the OVO application in Samarinda City, seen from Tcount > T table (4.648 > 1.969) and the sig value of 0.000 > 0.05, partially the security variable has no negative effect and not significant to Community Interest in Using OVO in Samarinda City, seen from Tcount < T table (-0.322 < 1.969) and sig value of 0.748 < 0.05, partially service feature variables have no significant negative effect on Community interest in using Ovo applications in the City Samarinda, seen from Tcount > Ttable (2,069 > 1,985) and the sig value of 0.041 > 0.05, simultaneously the convenience variable p use, risk, security and service features on public interest in using the OVO application in Samarinda City as seen from Fcount > Ftable (5,812 > 4,383) and a sig value of 0.000 < 0.05.
Analisis Perbandingan Kinerja Keuangan Pemerintah dalam Pengelolaan Anggaran Pendapatan dan Belanja Daerah (APBD) Kota Bontang Tahun 2014-2018
Authors: Sudarlan Sudarlan , Fitriana Rahmawati , Mujiato Rezky Dayanti 
Published: October 2023

This study aims to determine the financial performance of local revenue of Bontang City for the period 2014-2018. Thw Analytical tools used are revenue growth, the degree of decentralization, regional independency, the regional financial dependency, the effectiveness of local taxes, and the degree of contribution of the BUMD contributions as well spending growth, operating expenditure, capital expenditure, and expenditure efficiency. The results showed that the financial performance of Bontang's regional income in general had increased. Even so the regional financial performance of the Bontang city in terms of revenue in general is still not good. This is evidenced by the average growth of income experiencing negative growth of -1.69%, the degree of decentralization ratio is still lacking due to a percentage of 13.37%, the ratio of regional independence is very low due to a percentage of 16.26%, the ratio of regional financial dependence is very high due to a percentage of 87.18%, the ratio of effectiveness of effective local tax due to a percentage of 107.55%, and the degree of contribution of BUMD has contributed due to the percentage of 3.23% and regional expenditure in the city of Bontang in general can be said to be good. This is evidenced by the average growth of expenditure experienced a negative growth of -2.02, the ratio of operating expenditure to total expenditure dominated because of a percentage of 71.15%, the ratio of capital expenditure to total expenditure did not dominate due to a percentage of 28.23%, and efficient shopping efficiency ratio due to a percentage of 84.87%.
Pengaruh Pemahaman Bagi Hasil dan Kepercayaan terhadap Minat Menjadi Nasabah Bank Syariah Tahun 2022
Authors: Cahyono Aris Tri , Widyanto Eko Adi , Anjani Indah Alifia 
Published: October 2023

Penelitian ini bertujuan untuk menganalisis dan mengetahui faktor yang mempunyai pengaruh terhadap minat menjadi nasabah bank syariah karena dalam aktivitasnya bank sangat membutuhkan kepercayaan dari masyarakat. Alat analisis yang digunakan uji heteroskedasitas, analisis regresi linier berganda, uji T, Uji F dan Uji R2. Hasil penelitian ini menunjukan bahwa secara parsial variabel pemahaman bagi hasil, kepercayaan berpengaruh positif dan signifikan terhadap minat menjadi nasabah bank syariah. Secara simultan pemahaman bagi hasil dan kepercayaan terhadap minat menjadi nasabah bank syariah berpengaruh positif dan signifikan.
Archives Management System in the General Subdivision of the Regional Education Office of North Sulawesi Province
Authors: Jetty E. H. Mokat  , Goinpeace H. Tumbel  , Nanda A. Onibala  
Published: October 2023

This study aims to describe the filling management system in the general sub-section of the regional education office in North Sulawesi Province. This study uses a qualitative approach, with data collection techniques through observation, interviews, and documentation. The data obtained were analyzed by descriptive qualitative. The data source are the head of the General Sub-Division, employees and archive managers in the General Sub-Division at the Regional Education Office of North Sulawesi Province. The research results show that: 1). Archive storage procedures are not in accordance with the standards set in the law. Standard Operating Procedures (SOP) are ignored. To the knowledge of the Head of the existing Service they made everything in a structured way so that it is currently being tested. 2). Human Resources. There is no archivist or someone who has competence in the field of archiving, as a result the archives are not stored properly. 3). Facilities and infrastructure. Facilities and infrastructure as one of the requirements in the filing system/archive storage are inadequate. The existence of abandoned and unkempt facilities and infrastructure causes the management and storage of documents not up to standard. 4). Supervision and Control. Lack of supervision from the leadership makes the filing and storage management system not good, not organized. And the administration of archives is not in accordance with archival rules and standards.
Characteristics of Flow Hydrophysics Variables and Flood Potential Around Kuala Jengki Estuary Manado City
Authors: Maxi Tendean  , Grace F. E. Suoth  
Published: October 2023

Flood disasters along the river resulted from damage to flood barrier construction along the river bank. The damage to the flood retaining wall is technically caused by the very large hydrophysical parameters of the river flow. In theory, the flow mass density parameter shows the concentration of sediment transported through one cross-section. As a result of changes in the volume of sediment transport, there will be an increase in flow energy, followed by changes in large water masses, and this is seen as a destructive force component in some equivalent places or riverbanks, which can physically be formulated in the form of a model function. It is important to do a map of the hydrophysical character variable flow and flood potential along Kuala Jengki estuary Manado City, it is important to do because the estuary is often flooded. Measurement of the hydrophysical variable mass flow density was carried out at a depth of 0.6 rivers at high and low tides. The mass density of the flow is the mass of water containing transport sediment divided by its volume. The mass of water (sample) is measured using a scale, while the volume is measured using a measuring cup or another container that has a volume measurement. For the presentation of density data profiles and other analytical purposes, the measured data were reproduced using linear interpolation techniques. The mass density data modeling was carried out using an experimental function iteration technique containing constants. The results of the research at high tide, the position which is approximately 275 meters at measurement points 10 to 13 at a distance of 675 meters to 950 meters becomes a location that is very prone to river lip damage if there is a rise in water level due to high rainfall, or a position where it becomes flood-prone when the flow density increases, along with an increase in the volume of river water, which is followed by changes in river flow velocity carrying various types of sediment. At a distance of 165 meters at low tide, the measurement position is between 10 and 13, there is an increase in large flow discharge accompanied by an increase in flow velocity that carries flow mass (mass density) with various types of sediment transport. In this condition, the location which is 165 meters away according to the model map becomes prone to river lip damage, which means that it is a location that has the potential for flooding. In contrast to measurement positions 5 and 6 at high tide, there is a significant increase in the low mass density, while at low tide this condition does not occur, this is because the flow velocity at low tide does not change significantly, causing the mass flow density to be relatively the same.
ENHANCING STUDENTS’ READING COMPREHENSION THROUGH DISCOVERY LEARNING METHOD AT THE SEVENTH GRADE OF SMP HARAPAN 3 DELI SERDANG
Authors: Asrul Nurmahyuni 
Published: October 2023

The objective of this study was to enhance the reading comprehension of seventh-grade junior high school students through the implementation of the discovery learning method. The research engaged English teachers, school principals, and seventh-grade students from SMP Harapan 3 Deli Serdang. The study encompassed a total of 30 participants, comprising 10 boys and 20 girls. Employing a classroom action research approach, the investigation was executed in two distinct cycles following a pre-test. Collaborating closely with English teachers, the researchers conducted the Pedagogical Action (PTK) with a student population of 30. Analysis of the data from both Cycle I and Cycle II led to the following findings: during the pre-test, 10 students achieved a success rate of 33.5%, while 20 students scored a lower rate of 66.5%. In Cycle 1, the success rate increased to 43.5% for 13 students, with a corresponding failure rate of 56.5% among 17 students. In Cycle II, the success rate further improved, as 22 students attained a rate of 73.5%, whereas 8 students encountered a failure rate of 26.5%. In conclusion, this study demonstrates a consistent elevation in student scores, underscoring the effectiveness of the discovery learning method in enhancing reading comprehension among seventh-grade students at SMP Harapan 3 Deli Serdang. The findings indicate that this method holds substantial promise for educators dedicated to nurturing the reading proficiency of their students.
ANÁLISE DOS CUIDADOS DA PMPR COM OS FAMILIARES DOS POLICIAIS MILITARES
Authors: Ribeiro Douglas Wesley 
Published: October 2023

O ser humano possui, dentre outras características, uma série de sentimentos e vontades, assim como, o raciocínio. Dentre as complexidades que um indivíduo possui por si só, ainda surgem os obstáculos de conviver em sociedade. A família é uma das colunas da sociedade, onde se desenvolve o caráter do ser humano, bem como, os laços fraternos. A família pode influenciar a vida dos seus membros de várias maneiras, como por exemplo, motivá-los a enfrentarem os contratempos diários, tal como, incentivá-los nos momentos de conquistas. A sociedade por sua vez, pode também interferir na vida de um indivíduo de forma positiva ou até mesmo negativa, com isto, o local de trabalho do sujeito se apresenta como um campo onde os sentimentos, vontades e o intelecto do indivíduo podem ser influenciados. Tendo em mente que existe uma associação entre família e trabalho se torna necessária a pesquisa que harmonize esta conexão. A Polícia Militar do Paraná, tem desenvolvido projetos para melhor acolher seus membros e também os familiares destes, trazendo assim, bem-estar para ambos.
EFFECTS OF AIRLINES ZERO COMMISSION ON THE PERFOMANCE OF TRAVEL AGENTS: A SURVEY OF AIR TRAVEL AGENTS IN NAIROBI CBD
Authors: Stephen Victoria 
Published: October 2023

Purpose: The study was an assessment of the effects of airline zero commission on the performance of travel agents.
Methodology: A descriptive survey of air travel agents in Nairobi CBD was taken. A population of 350 travel agents was identified out of which a sample of (35) 10% were randomly selected.
Results: Findings indicate that travel agents had been affected by the Zero commission. Their profitability, customer satisfaction, employee morale and internal processes were affected negatively. Findings also indicated that charging fees, cost leadership, differentiation, specializing in geographical areas or becoming niche players for specific leisure products, improvement in customer service and increased marketing and communication , expansion of the product base , strategic partnership and external linkages with other service providers were some of the strategic responses being adopted by travel agents. Findings also indicated that Travel agents have increased investment in financial resources, human resources, knowledgeable and creative workforce, and improvement in brand name, a unifying corporate culture, robust IT infrastructure and corporate governance as an effort to recover from the zero commission problems. The study recommends that the travel agents continue using generic strategies and tailor-made strategic responses as this would help them to deal with the problem of zero commission. In addition, the travel agents should also differentiate their products in order to attract more customers. The travel agents also need to continue charging fees and ensure that they deliver good customer service to travelers.
Unique Contribution to Theory and Practice: The study recommends that the travel agents continue using generic strategies and tailor-made strategic responses as this would help them to deal with the problem of zero commission. In addition, the travel agents should also differentiate their products in order to attract more customers. The travel agents also need to continue charging fees and ensure that they deliver good customer service to travelers.
INFLUENCE OF SHARE CAPITAL AND PREFERRED STOCK ON FINANCIAL PERFORMANCE OF BANKS LISTED IN THE NAIROBI SECURITIES EXCHANGE, KENYA
Authors: Githinji Robert 
Published: October 2023

Purpose: The purpose of this paper was to examine the influence of share capital and preferred stock on the financial performance of listed banks in Nairobi Securities Exchange (NSE).
Methodology: The study adopted a cross-sectional survey research design. It targeted all the eleven commercial banks listed at the NSE. The research used a datasheet to collect secondary data. This implies that the study entirely used secondary data, which was obtained from the financial records of the targeted banks. The study used census, meaning that all the banks listed in the NSE were included in the study. Data was analyzed using both descriptive and inferential statistics. Pearson’s product moment correlation was used to indicate the hypothesized influence of share capital and preferred stock on financial performance. The findings were organized, summarized and presented using tables and charts.
Results: Correlation results indicated a strong positive relationship of r=0.873 and P=0.000 between share capital and financial performance, as well as a strong positive relationship at r=0.851 and P=0.001 between preferred stock and financial performance. The study concluded that the banks’ financial performance was dependent on their share capital which was used as a source of equity financing. The more a bank injects share capital into its finances, the more likely it will improve its overall financial performance. The study recommended the use of share capital as source of equity financing in commercial banks as it is an efficient source of financing to such institutions.
Unique Contribution to Theory, Practice & Policy: The study contributed theory by indicating that the value or performance of firms does not solely depend on internal sources but some combination of both internal and external sources could be necessary. As such banks and their management should look for the best combination and optimal levels of internal and external financing that would steer their firms to success.
INFLUENCE OF DIVESTMENT STRATEGY ON PERFORMANCE OF LARGE MANUFACTURING FIRMS IN KENYA
Authors: Kithinji Jacob , Rotich Gladys , Kihara Allan 
Published: October 2023

Purpose: The study sought to establish the influence of divestment strategy on the performance of manufacturing firms in Kenya. This comes at a time when manufacturing firms in Kenya have been experiencing declining performance in terms of revenue, sales and the profit margins. While the firms have tried to come up with different strategies to salvage their performance, it is not clear whether they have embraced divestment as one of the turnaround strategies, hence the subject of the study.
Methodology: This study was informed by real options theory. Descriptive research design was used in the study. The target population was the 708 large manufacturing firms in Kenya. The sample size for the study was 249 firms selected randomly from all the 14 sub-sectors of the manufacturing industry in Kenya. The data collection instrument was a questionnaire. The collected data was analyzed using descriptive and inferential statistics.
Results: The findings revealed that divestment strategy had a significant and positive influence on the performance of large manufacturing firms in Kenya. The study concluded that through divestment, manufacturing firms are able to save on costs and redirect their revenues to more productive and profitable processes, thus enhancing performance.
Unique Contribution to Theory, Practice and Policy: The management of manufacturing companies should embrace divestment strategy through disposing some of their assets that are not generating profits and exiting any market that is least performing. This way, the companies raise more funds and save on costs used in running less beneficial products or services.