bluuebunny/crossref_metadata_2025_split huggingface dataset:
On the Importance of Service Parts When Taking Commonality and Reliability Decisions
Authors: Driessen Joni , Arts Joachim , van Houtum Geert-Jan 
Published: February 2024

Competitive Original Equipment Manufacturers (OEMs) do not only sell equipment, but also provide service contracts that ensure proper functioning and uptime of equipment after the sale. This makes OEMs responsible for a large part of an equipment’s life cycle. Therefore, OEMs aim to minimize the total life cycle costs of their equipment, in particular by commonality and reliability level decisions during the design phase. We consider these decisions for one component occurring in a family of systems. The commonality decision is about choosing a common component or dedicated components for the systems. The life cycle costs consist of design and production costs of all components, repair costs, inventory holding costs of service parts, and logistic downtime costs (i.e., downtime costs due to insufficient spare parts inventory). At many OEMs, the design department tends to exclude service parts considerations for the commonality and reliability level decisions. Excluding service parts leads to a simpler decision model, however, this may lead to non–optimal decisions. We compare two approaches for the commonality and reliability decisions: the anticipating approach, which includes inventory holding costs of service parts and logistic downtime costs, and the nonanticipating approach, which excludes these costs. Since the cost function under the anticipating approach is intractable, we first derive a cost function that approximates the actual costs via an asymptotic analysis. Next, we show that the anticipating approach selects the common component more frequently in comparison with the nonanticipating approach. For many problem instances, the nonanticipating approach leads to decisions that have a much higher overall cost than using the anticipating approach. The relative cost difference can become arbitrarily large when the family of systems consists of many systems. Funding: J. Driessen was funded by the Netherlands Organisation for Scientific Research [Grant 407-12-001].
Difference of carrier dynamics in a semiconductor saturable absorber mirror with and without B+ ion-implantation
Authors: Wang Meng , You Si-Qi , Cheng Yu-Nuo , Liu Qing-Yu , Wang Yong-Gang , Chen Jun-Ru , Sun Yang , Lin Nan , Huang Ting , Ma Xiao-Yu 
Published: February 2024

Three samples whose growth temperatures were 450°C, 500°C, and 560°C for SESAM1, SESAM2, and SESAM3, respectively, were tested by femto-second time-resolved transient absorption spectroscopy. The results indicate that the carrier dynamics of excited state absorption were dominant, and the lifetimes of carriers trapped by defect levels were about tens of pico-seconds. To further study the influence of carrier dynamics and recovery time of samples by ion-implantation, B+ ions of 80 and 130 KeV were implanted into the samples with dose of 1014/cm2. The modified samples showed a dominance of ultra-fast carrier dynamics of ground-state bleaching and direct recombination, which lasted for hundreds of femto-seconds, over excited state absorption. Additionally, carrier fast trapping was observed to be competitive with the excited state absorption process. After ion-implantation, the carrier dynamics of carrier trapping were enhanced, which contributed to forming an ultra-short laser, while the carrier dynamics of absorption of the excited state were suppressed. The conclusion that defect levels were partially eliminated by B+ ion-implantation can be drawn.
Self-injection-locked optical parametric oscillator based on microcombs
Authors: Lei Fuchuan , Sun Yi , Helgason Óskar B. , Ye Zhichao , Gao Yan , Karlsson Magnus , Andrekson Peter A. , Torres-Company Victor 
Published: February 2024

Narrow-linewidth yet tunable laser oscillators are one of the most
important tools for precision metrology, optical atomic clocks,
sensing, and quantum computing. Commonly used tunable coherent
oscillators are based on stimulated emission or stimulated Brillouin
scattering; as a result, the operating wavelength band is limited by
the gain media. Based on nonlinear optical gain, optical parametric
oscillators (OPOs) enable coherent signal generation within the whole
transparency window of the medium used. However, the demonstration of
OPO-based Hertz-level linewidth and tunable oscillators has remained
elusive. Here, we present a tunable coherent oscillator based on a
multimode coherent OPO in a high-Q microresonator, i.e., a
microcomb. Single-mode coherent oscillation is realized through
self-injection locking (SIL) of one selected comb line. We achieve
coarse tuning up to 20 nm and an intrinsic linewidth down to
sub-Hertz level, which is three orders of magnitude lower than the
pump. Furthermore, we demonstrate that this scheme results in the
repetition rate stabilization of the microcomb. These results open
exciting possibilities for generating tunable coherent radiation where
stimulated emission materials are difficult to obtain, and the
stabilization of microcomb sources beyond the limits imposed by the
thermorefractive noise in the cavity.
Physical activity status and its association with quality of life among children with down syndrome in Saudi Arabia: A comparative cross-sectional study
Authors: Alqahtani Amani S. , Algabbani Maha F. , Alhammad Saad A. , Alwadeai Khalid S. , Alhusaini Adel 
Published: February 2024

Background
Down syndrome is a genetic disorder that causes physical and cognitive challenges. Identifying the impact of sedentary behavior and physical activity on people with Down syndrome is crucial for early intervention. The purpose of this study is to compare physical activity and sedentary behavior among children with Down syndrome and typically developing children, as well as assess their relationship with quality of life.

Methods
In the cross-sectional study, 67 children between the ages of 6 and 12 were enrolled: 29 in the Down syndrome group and 38 in the typically developing group. Each child wore an ActiGraph wGT3X-BT for seven days. Accelerometer data and quality of life data were analysed.

Results
Physical activity and sedentary behavior were not significantly different between the Down syndrome and typically developing groups (p ˃ .05). With large effect sizes (partial eta squares ranging from 0.21 to 0.59), typically developing children had a significantly better quality of life than children with Down syndrome. There was a weak positive correlation between moderate physical activity and school performance in children with Down syndrome. For typically developing children, there is a weak negative correlation between light physical activity and physical function, school function, and total paediatric quality of life scale scores.

Conclusions
This study indicates that children with Down syndrome have participated in more physical activities, resulting in a reduction in differences between them and typically developing children. Additionally, typically developing had higher quality of life than children with Down syndrome. For healthcare professionals and educators, these findings provide valuable insights into developing strategies to enhance physical activity for children with developmental disabilities.
Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in the Elderly with Alzheimer’s Disease (D-PRESCRIBE-AD): Trial protocol and rationale of an open-label pragmatic, prospective randomized controlled trial
Authors: Singh Sonal , Cocoros Noelle M. , Li Xiaojuan , Mazor Kathleen M. , Antonelli Mary T. , Parlett Lauren , Paullin Mark , Harkins Thomas P. , Zhou Yunping , Rochon Paula A. , Platt Richard , Dashevsky Inna , Massino Carly , Saphirak Cassandra , Crawford Sybil L. , Gurwitz Jerry H. 
Published: February 2024

Context
Potentially inappropriate prescribing of medications in older adults, particular those with dementia, can lead to adverse drug events including falls and fractures, worsening cognitive impairment, emergency department visits, and hospitalizations. Educational mailings from health plans to patients and their providers to encourage deprescribing conversations may represent an effective, low-cost, “light touch”, approach to reducing the burden of potentially inappropriate prescription use in older adults with dementia.

Objectives
The objective of the Developing a PRogram to Educate and Sensitize Caregivers to Reduce the Inappropriate Prescription Burden in Elderly with Alzheimer’s Disease (D-PRESCRIBE-AD) trial is to evaluate the effect of a health plan based multi-faceted educational outreach intervention to community dwelling patients with dementia who are currently prescribed sedative/hypnotics, antipsychotics, or strong anticholinergics.

Methods
The D-PRESCRIBE-AD is an open-label pragmatic, prospective randomized controlled trial (RCT) comparing three arms: 1) educational mailing to both the health plan patient and their prescribing physician (patient plus physician arm, n = 4814); 2) educational mailing to prescribing physician only (physician only arm, n = 4814); and 3) usual care (n = 4814) among patients with dementia enrolled in two large United States based health plans. The primary outcome is the absence of any dispensing of the targeted potentially inappropriate prescription during the 6-month study observation period after a 3-month black out period following the mailing. Secondary outcomes include dose-reduction, polypharmacy, healthcare utilization, mortality and therapeutic switching within targeted drug classes.

Conclusion
This large pragmatic RCT will contribute to the evidence base on promoting deprescribing of potentially inappropriate medications among older adults with dementia. If successful, such light touch, inexpensive and highly scalable interventions have the potential to reduce the burden of potentially inappropriate prescribing for patients with dementia.
ClinicalTrials.gov Identifier: NCT05147428.
Ceragenin-mediated disruption of Pseudomonas aeruginosa biofilms
Authors: Wnorowska Urszula , Łysik Dawid , Piktel Ewelina , Zakrzewska Magdalena , Okła Sławomir , Lesiak Agata , Spałek Jakub , Mystkowska Joanna , Savage Paul B. , Janmey Paul , Fiedoruk Krzysztof , Bucki Robert 
Published: February 2024

Background
Microbial biofilms, as a hallmark of cystic fibrosis (CF) lung disease and other chronic infections, remain a desirable target for antimicrobial therapy. These biopolymer-based viscoelastic structures protect pathogenic organisms from immune responses and antibiotics. Consequently, treatments directed at disrupting biofilms represent a promising strategy for combating biofilm-associated infections. In CF patients, the viscoelasticity of biofilms is determined mainly by their polymicrobial nature and species-specific traits, such as Pseudomonas aeruginosa filamentous (Pf) bacteriophages. Therefore, we examined the impact of microbicidal ceragenins (CSAs) supported by mucolytic agents–DNase I and poly-aspartic acid (pASP), on the viability and viscoelasticity of mono- and bispecies biofilms formed by Pf-positive and Pf-negative P. aeruginosa strains co-cultured with Staphylococcus aureus or Candida albicans.

Methods
The in vitro antimicrobial activity of ceragenins against P. aeruginosa in mono- and dual-species cultures was assessed by determining minimum inhibitory concentration (MIC) and minimum bactericidal/fungicidal concentration (MBC/MFC). Inhibition of P. aeruginosa mono- and dual-species biofilms formation by ceragenins alone and in combination with DNase I or poly-aspartic acid (pASP) was estimated by the crystal violet assay. Additionally, the viability of the biofilms was measured by colony-forming unit (CFU) counting. Finally, the biofilms’ viscoelastic properties characterized by shear storage (G’) and loss moduli (G”), were analyzed with a rotational rheometer.

Results
Our results demonstrated that ceragenin CSA-13 inhibits biofilm formation and increases its fluidity regardless of the Pf-profile and species composition; however, the Pf-positive biofilms are characterized by elevated viscosity and elasticity parameters.

Conclusion
Due to its microbicidal and viscoelasticity-modifying properties, CSA-13 displays therapeutic potential in biofilm-associated infections, especially when combined with mucolytic agents.
Electoral Dynamics for 2022: The House of Representatives in the Modern Era
Authors: Wagner Regina L. , Shafer Byron E. 
Published: February 2024

Abstract
Politically, the mid-term election of 2022 not only switched partisan control of one of the major branches of American national government but shifted party balance within that government as a whole. Yet analytically, this resulted from a shift in the House of Representatives so minute – 9 seats changed hands in a body of 435 members – that many of the usual tools for dissecting American elections had nothing to say. Which means at a minimum that analysis of this particular contest requires some larger, nested framework for its interpretation. This paper is an attempt to provide one such framework.
Insight into heating method and Mozafari method as green processing techniques for the synthesis of micro- and nano-drug carriers
Authors: Jalilian Zahra , Mozafari M. R. , Aminnezhad Sargol , Taghavi Elham 
Published: February 2024

Abstract
Drug delivery systems, also known as bioactive carriers, are currently an important contribution to the pharmaceutical and biomedical industries. A leading category of these drug carriers is lipid- and phospholipid-based systems including liposomes, nanoliposomes, solid lipid nanoparticles, nanostructured lipid vesicles, archaeosomes, and tocosomes. At present, there are several methods available for the preparation of the lipidic drug carriers at the micro- and nanoscales. There are some misunderstandings and confusion in the literature regarding two of the scalable and environment-friendly (green) techniques developed in our laboratory, namely the heating method and the Mozafari method. These methods are superior to conventional procedures used in the synthesis of drug carriers due to the fact that they do not involve utilization of potentially toxic solvents, detergents, or high-shear homogenizations. This entry is aimed to clarify differences between these methods to the peers and colleagues in academia as well as relevant industries. Some details of the industrially applied patented instrument used in the manufacturing of lipidic carriers are also provided.
Effect of copper powder addition on the product quality of sintered stainless steels
Authors: Yılmaz Mustafa Safa , Kayacan Mevlüt Yunus , Üzün Ahmet 
Published: February 2024

Abstract
Powder metallurgy and selective laser melting (SLM) methods are widely used in producing metal parts. Adding reinforcements can improve the mechanical and physical properties of the parts. This study uses the powder metallurgy method before SLM to investigate the effect of copper reinforcement (0, 0.5, 1, 2, and 5 wt.%) on 316L and MS1 (maraging steel) material. The study started by thermochemical investigating the effects of copper addition on the phases during cooling. According to the thermochemical analysis, experimental sintering processes were carried out with the addition of copper in suitable mixing ratios. The findings show that 316L material is more convenient to the sinter than MS1 due to alloy ratios and powder sizes. Adding up to 2 wt.% copper to 316L results in a 36 wt.% reduction in linear shrinkage and improved mechanical and physical stability. The most satisfactory results were obtained by sintering the samples at 1200 °C for 1 h. This study shows that future research should focus on producing copper-reinforced 316L metal powders using SLM methods and parameter optimization and developing hybrid manufacturing methods that combine SLM with powder metallurgy.
Improved nonlinear model predictive control with inequality constraints using particle filtering for nonlinear and highly coupled dynamical systems
Authors: Ahsan Muhammad , Salah Mostafa M. 
Published: February 2024

Abstract
Motion planning and controller design are challenging tasks for highly coupled and nonlinear dynamical systems such as autonomous vehicles and robotic applications. Nonlinear model predictive control (NMPC) is an emerging technique in which sampling-based methods are used to synthesize the control and trajectories for complex systems. In this study, we have developed the sampling-based motion planning algorithm with NMPC through Bayesian estimation to solve the online nonlinear constrained optimization problem. In the literature, different filtration techniques have been applied to extract knowledge of states in the presence of noise. Due to the detrimental effects of linearization, the Kalman filter with NMPC only achieves modest effectiveness. Moving horizon estimation (MHE), on the other hand, frequently relies on simplifying assumptions and lacks an effective recursive construction. Additionally, it adds another optimization challenge to the regulation problem that has to be solved online. To address this problem, particle filtering is implemented for Bayesian filtering in nonlinear and highly coupled dynamical systems. It is a sequential Monte Carlo method that involves representing the posterior distribution of the state of the system using a set of weighted particles that are propagated through time using a recursive algorithm. For nonlinear and strongly coupled dynamical systems, the novel sampling-based NMPC technique is effective and simple to use. The efficiency of the suggested method has been assessed using simulated studies.
A novel framework for effective structural vulnerability assessment of tubular structures using machine learning algorithms (GA and ANN) for hybrid simulations
Authors: Zain Muhammad , Prasittisopin Lapyote , Mehmood Tahir , Ngamkhanong Chayut , Keawsawasvong Suraparb , Thongchom Chanachai 
Published: February 2024

Abstract
Seismic vulnerability assessments are conventionally conducted by using sophisticated nonlinear analytical models, leading to aggressive computational demands. Previous attempts were made to reduce computational efforts for establishing vulnerability assessment of structures; however, the area of super tall and tubular structures still faces considerable lack. Advent of efficient machine learning (ML) has enabled engineering practitioners to automate the processes for fragility analysis; however, its application for high-rise tubular structures is not yet exploited, and most implementations are limited to basic ML. In this work, an attempt was made to reduce computational demand for the fragility assessment process for tubular structures by employing genetic algorithms (GAs) for nonlinear structural modeling, and development of artificial neural network (ANN) using deep learning for fragility development. Consequently, a simple lumped parameter model had been developed using open-source code of ZEUS-NL, containing parameters selected by GA to acutely account for convoluted interactive behavior of structural systems and dynamic demands. Subsequently, incremental dynamic analysis (IDA) was performed on the optimized model. A new framework has been established to develop and train ANN architecture by amalgamating Weka’s capability of data preprocessing with deep learning. The established ANN model resulted in correlation coefficient of 0.9972 and R
2 of 0.95, demonstrating adequate performance.
Preparation and characterization of nanocellulose acetate and acrylate polymer composite membrane
Authors: Wang Jiale , Qiu Xianglin , Lang Xukang , Gao Shanshan , Song Xiaoming , Chen Fushan 
Published: February 2024

Abstract
In the present study, a nanocellulose acetate and acrylate polymer composite membrane was formed by the phase transfer technique. The physical and mechanical properties, water flux, and desalination performance of the achieved composite membrane were investigated. When 3 % (w/w) acrylate polymer, 10 % acetylated nanocellulose, and 0.3 % mass fraction of TiO2 were used for the formation of the membrane, the obtained product could reach a tensile strength of 1.97 N/mm2 and a pure water flux of 51 L/(m2 h). Moreover, the composite membrane achieved a desalination rate of 92.4 %. Thus, the obtained composite membrane could meet the performance requirements for the treatment of industrial wastewater.
ВПЛИВ ІОНІВ Fe3+ ТА АНОДНОГО ПРОЦЕСУ НА ЛОКАЛЬНЕ ЕЛЕКТРООСАДЖЕННЯ МІДІ В СИСТЕМАХ ЕЛЕКТРОХІМІЧНОГО 3D-ДРУКУ
Authors: Ущаповський Дмитро Ю. , Васильєв Георгій С. , Лінючева Ольга В. , Плясовська Антоніна В. , Воробьйова Вікторія І. , Забалуєв Андрій С. 
Published: February 2024

Досліджено вплив сторонніх катодних процесі та анодних матеріалів на вихід за струмом міді в сульфатному електроліті та точність електрохімічного 3D-друку. Встановлено, що наявність в електроліті 10 г/дм3 іонів Fe3+ по-різному впливає на вихід за струмом міді в комірках з активним мідним та інертним свинцевим анодами. В інтервалі густин струму 5…7 А/дм2 вихід за струмом міді в електрохімічній комірці з мідним анодом не перевищує 86…88 %, у той же час, для комірки зі свинцевим анодом він становить 96…97 %. За густини струму 1 А/дм2 навпаки в комірці зі свинцевим анодом вихід за струмом зменшується до 65 %, а в комірці з мідним анодом – до 72 %. Відмінність у значеннях виходу за струмом та ході отриманих логарифмічних залежностей виходу за струмом від густини струму може бути пов’язана з впливом анодного процесу виділення кисню на свинцевому електроді на побічний процес відновленні іонів Fe3+. Окисна дія анодно продукованого кисню по відношенню до останніх, а також підлуговування прикатодного шарупризводить до утворення малорозчинних сполук заліза (ІІІ) і пригнічення їх відновлення в області високих значень катодних густин струму. Таким чином, в комірці з інертним свинцевим анодом наявність у розчині іонів Fe3+ призводить до зниження виходу за струмом міді в області малих значень густин струму, це є фактором підвищення локалізації електроосадження та точності електрохімічного 3D-друку. Моделювання профілю тривалого росту локально електроосаджуваного фрагменту мідного осаду в середовищі COMSOL Multiphysics з урахуванням виходу за струмом та результатів поляризаційних вимірювань показало наступне. Введення в електроліт іонів Fe3+ зумовлює зменшення нахилу катодної поляризаційної кривої та відповідно призводить до збільшення розсіювальної здатності електроліту, що більш виражено проявляється в електролізері з мідним анодом. Зниження товщини осаду металу в області низьких значень густин струму відображується лише при моделюванні профілю росту металевого осаду для комірки зі свинцевим інертним анодом.
Ключові слова: електрохімічний 3D-друк; сульфатний електроліт; розсіювальна здатність; іони Fe3+; масоперенесення.