bluuebunny/crossref_metadata_2025_split huggingface dataset:
Viral cytopathic changes in urine cytology of ileal conduit attributed to adenovirus: Report of a case
Authors: Zaharopoulos Paul 
Published: March 2004

AbstractUrine cytology from ureteral diversions utilizing intestinal segment as reservoir or conduit, constructed during cystectomy performed usually for advanced bladder neoplasia, differs from bladder urine cytology in that the presence of abundant intestinal mucosal cells with degenerative and inflammatory changes interferes with the recognition of other important cellular changes, particularly of recurrent neoplasia in the upper urinary tract, not to mention other less frequent yet note worthy pathologic changes, such as viral type indigenous to the urinary tract. When confronted with diseases involving the intestinal segment, such as viral enteritides, the diagnostic problem becomes more complex and special effort is needed to recognize and characterize them correctly, differentiating them from other pathologies or artifacts seen in such specimens. We report one such case in which viral changes affecting columnar intestinal epithelium were identified and by immunocytochemistry characterized as adenoviral involving primarily cells of the intestinal conduit. We discuss the significance of such infection in comparison to other viral changes indigenous to the urinary tract, which could also occur in such specimens. Diagn. Cytopathol. 2004;30:284–287. © 2004 Wiley‐Liss, Inc.
Incidence of severe anorexia nervosa in Switzerland: 40 years of development
Authors: Milos Gabriella , Spindler Anja , Schnyder Ulrich , Martz Jan , Hoek Hans Wijbrand , Willi Jürg 
Published: March 2004

AbstractObjectiveThe current study examined the development of the incidence of severe anorexia nervosa with five sampling periods covering the years 1956–1995 in a geographically defined region of Switzerland.MethodApplying the same methodology as in the earlier sampling periods, the medical records of all hospitals of the canton of Zurich were screened manually for first‐time hospitalizations of female anorexia nervosa patients during the years 1993–1995. Incidence rates were compared with the previous sampling period (1956–1985).ResultsThe incidence rate of severe anorexia nervosa in the total population and the rate in the population at risk (females 12–25 years old) did not differ significantly from the incidence rates of 1983–1985.DiscussionThe incidence of severe anorexia nervosa in the canton of Zurich rose significantly during the 1960s and 1970s. Since then, the incidence appears to have reached a plateau. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 35: 250–258, 2004.An erratum to this article is published in International Journal of Eating Disorders (2004) 36(1) 118–119.
A prospective study of disordered eating among sorority and nonsorority women
Authors: Allison Kelly C. , Park Crystal L. 
Published: March 2004

AbstractObjectiveThe current study examined disordered eating prospectively among sorority and nonsorority women.MethodUniversity women were surveyed during their first, second, and third undergraduate years. Disordered eating, depression, self‐esteem, body mass index (BMI), and ideal weight were measured.ResultsDisordered eating did not differ between the groups before women joined sororities. By Time 3, sorority women reported higher Eating Disorder Inventory (EDI) Drive for Thinness subscale scores than nonsorority women, but the EDI Bulimia and Body Dissatisfaction subscales did not differ. BMI, ideal weights, depression, and self‐esteem did not differ.ConclusionsWomen who join sororities are similar to those who do not in their baseline levels of disordered eating, but they maintain more rigorous attitudes and behaviors regarding dieting over the course of their higher education. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 35: 354–358, 2004.
Inducible syncope in anorexia nervosa: Two case reports
Authors: Buchowski Katherine P. , Pardo Jennifer , Ringel Richard , Guarda Angela S. 
Published: March 2004

AbstractObjectiveSyncope is a potentially dangerous symptom of anorexia nervosa that is usually attributed to bradycardia, dehydration, or hypoglycemia.MethodsThis study describes two adolescents, one male and one female, with recurrent self‐induced syncope associated with isometric exercise.ResultsIn one patient, Holter monitoring showed that isometric exercise led to increasing bradycardia followed by asystolic pauses accompanied by presyncopal symptoms.DiscussionWe hypothesize that inducible syncope in these two patients is due to increased vagal tone and baroreceptor sensitivity. Physicians should be aware that patients with anorexia nervosa may be able to induce syncope with isometric exercise and that this potentially dangerous behavior needs to be addressed during treatment. © 2004 by Wiley Periodicals, Inc. Int J Eat Disord 35: 359–362, 2004.
Nitrogen Trifluoride as a Bifunctional Lewis Base: Implications for the Adsorption of NF3 on Solid Surfaces
Authors: Antoniotti Paola , Borocci Stefano , Grandinetti Felice 
Published: March 2004

AbstractThe structure, stability, and thermochemistry of isomeric adducts between NF3 and the Lewis acids BH3−nFn (n = 0−3) have been investigated at the coupled‐cluster and at the Gaussian‐3 (G3) level of theory. At the CCD/cc‐pVDZ level both the nitrogen‐ and the fluorine‐coordinated structures of all BH3−nFn−(NF3) (n = 0−3) adducts were characterized as true minima on the potential energy surface, thus providing the first theoretical evidence for the behavior of NF3 as a bifunctional Lewis base when interacting with neutral Lewis acids. At the G3 level, and 298.15 K, including the contribution of the entropy term, the H3B−NF3 adduct is predicted to be more stable than H3B−F−NF2 by 4.3 kcal mol−1; this free energy difference is 3.7 kcal mol−1 at the CCSD(T)/cc‐pVTZ//CCD/cc‐pVDZ level of theory. Conversely, at the latter computational level, the fluorine‐coordinated isomers of the BH2F−(NF3), BHF2−(NF3), and BF3−(NF3) adducts are practically degenerate with the nitrogen‐coordinated ones. BH3−nFn−(NF3) (n = 0−3) complexes feature typical bond dissociation energies of ca. 1−2 kcal mol−1, and are predicted to be thermodynamically stable only at low temperatures. However, the appreciable influence of the basis set superposition error (BSSE) prevents a quantitative assessment of these small computed dissociation energies. Finally, we briefly discuss the implications of our calculations for the adsorption of NF3 on solid surfaces. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Hybrid Cyclic Dimers of Divacant Heteropolyanions: Synthesis, Mass Spectrometry (MALDI‐TOF and ESI‐MS) and NMR Multinuclear Characterisation
Authors: Mayer Cédric R. , Hervé Maryline , Lavanant Hélène , Blais Jean‐Claude , Sécheresse Francis 
Published: March 2004

AbstractIn the field of organic‐inorganic hybrid composites, functionalized polyoxometalates constitute a special class of inorganic nanobuilding blocks (NBBs). This study represents a first approach related to the formation of new oligomeric hybrid species based on the reaction of bis(electrophilic) groups with a divacant heteropolyanion as the NBB. Bis(phosphonates) such as para‐H2O3PCH2(C6H4)nCH2PO3H2 (n = 1 or 2) have been treated with the divacant heteropolyanion [γ‐SiW10O36]8− to form the hybrid cyclic dimer [H2{(SiW10O36)(O=PCH2(C6H4)nCH2P=O)}2]6−. MALDI‐TOF and ESI mass spectrometry have been used as essential analytical techniques for the characterization of such composite systems. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Fast, High‐Yielding Syntheses of Silsesquioxanes Using Acetonitrile as a Reactive Solvent
Authors: Pescarmona Paolo P. , van der Waal Jan C. , Maschmeyer Thomas 
Published: March 2004

AbstractNew and efficient methods for the synthesis of cyclopentyl‐ and cyclohexylsilsesquioxanes are described. In the case of cyclopentylsilsesquioxane, pure trisilanol (c‐C5H9)7Si7O9(OH)3 was obtained selectively within 18 h in an isolated yield of 64%. The synthesis of cyclohexylsilsesquioxanes also gives high yields, but it is not selective towards a particular structural type [main products: (c‐C6H11)6Si6O9, (c‐C6H11)6Si6O8(OH)2, (c‐C6H11)7Si7O10OH and (c‐C6H11)7Si7O9(OH)3]. We discuss the crucial role of acetonitrile as a reactive solvent in these syntheses. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
On the Use of the Bis(diiodine) Adduct of 1,4‐Dimethylperhydro‐1,4‐diazepine‐2,3‐dithione (Me2dazdt) to Recover Liquid Mercury Producing [Hg(Me2dazdt)I2] in a One‐Step Reaction
Authors: Bigoli Francesco , Cabras Maria Cristina , Deplano Paola , Mercuri Maria Laura , Marchiò Luciano , Serpe Angela , Trogu Emanuele F. 
Published: March 2004

AbstractDiiodine adducts with cyclic dithio‐oxamides, where complexing and oxidising properties coexist in the same molecule, have been shown to be powerful oxidising reagents towards selected metals. Here we describe the reaction of Me2dazdt·2I2 [Me2dazdt = 1,4‐dimethylperhydro‐1,4‐diazepine‐2,3‐dithione (1)] with highly toxic liquid mercury which gives the complex [Hg(Me2dazdt)I2] (2) in a one‐step reaction. X‐rays analysis of 2 shows that the HgII centre is coordinated by two sulfur atoms of the chelating ligand and by two iodine atoms in a distorted tetrahedral geometry. The molecule is asymmetric and crystallizes in the chiral space group P212121. In the unit cell only the M enantiomer is present [τ (S1−C1−C2−S2) = −61.1(5)°]. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Asymmetric Heterodinuclear FeIIIMII (M = Zn, Cu, Ni, Fe, Mn), CoIIIFeII and FeIICoIII Species: Synthesis, Structure, Redox Behavior, and Magnetism
Authors: Ross Sylvia , Weyhermüller Thomas , Bill Eckhard , Bothe Eberhard , Flörke Ulrich , Wieghardt Karl , Chaudhuri Phalguni 
Published: March 2004

AbstractReactions of an LFeIII unit with an M(PyA)3n− ion prepared in situ, where L represents 1,4,7‐trimethyl‐1,4,7‐triazacyclononane and PyA− is the monoanion of pyridin‐2‐aldoxime, yield heterodinuclear cations of the general formula [LFeIII(PyA)3M]2+, where M = ZnII (1), CuII (2), NiII (3), low‐spin FeII (4) and MnII (5). Additionally, we also prepared the diamagnetic species [LCoIII(PyA)3FeII]2+ (6). The FeIIICoII species could not be isolated because a facile intramolecular electron transfer leads to complex 7, [LFeII(PyA)3CoIII]2+. Compounds 1−7 contain three oximato anions as bridging ligands and are isostructural in the sense that they all contain a terminal metal(III) ion in a distorted octahedral environment (e.g., FeN3O3) and a second six‐coordinate metal ion M in a mostly trigonal‐prismatic MN6 geometry. Complexes 1−7 were characterized on the basis of elemental analyses, mass spectrometry, IR, UV/Vis, Mössbauer, and EPR spectroscopy, and variable‐temperature (2−295 K) magnetic susceptibility measurements. The solid‐state structures of 1−7 have also been determined by X‐ray crystallography. The cyclic voltammograms of the complexes reveal both ligand‐centered and metal‐centered redox processes. Analysis of the susceptibility data indicates the presence of antiferromagnetic exchange interactions that decrease in the following order: FeIIICuII (2) > FeIIINiII (3) > FeIIIMnII (5), as is expected. We have used X‐band EPR spectroscopy of 3 (FeIIINiII) at 2−6 K to establish the electronic ground state in great detail and to complement the magnetic susceptibility measurements. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Epoxidation versus Baeyer−Villiger Oxidation: The Possible Role of Lewis Acidity in the Control of Selectivity in Catalysis by Transition Metal Complexes
Authors: Brunetta Agostino , Strukul Giorgio 
Published: March 2004

AbstractThe synthesis of a series of cationic complexes of PtII containing triphos or triphosPO and either a solvent, a hydroxo or a hydroperoxo as the fourth ligand is reported. The complexes are characterized by IR and 31P{1H} NMR spectroscopy and by molar conductivity data, and their Lewis acid characteristics determined by NMR techniques. All complexes are good catalysts for the epoxidation of olefins and the Baeyer−Villiger oxidation of ketones under mild conditions using hydrogen peroxide as oxidant. The latter reaction is more Lewis‐acid demanding in terms of the electronic characteristics of the catalysts. The use of Lewis‐acidic metal centers allows the selective oxidation of unsaturated ketones to the corresponding unsaturated esters without oxidation of the carbon‐carbon double bond, indicating that a strong Lewis‐acid character of the catalyst can be an important feature in the design of catalysts capable of separating the two processes. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Dinuclear Potassium‐Chromium and Potassium‐Tungsten Carbonyl Complexes
Authors: Kirin Vladimir , Roesky Peter W. 
Published: March 2004

AbstractThe tetracarbonyl complexes [M(CO)4{η2‐(Ph2P)2NH}] [M = Cr (1a), W (1b)] have been synthesised by reaction of M(CO)6, Me3NO·2H2O, and (Ph2P)2NH. Subsequent treatment of complexes 1a,b with an excess of KH in THF at room temperature yields the potassium salts [Cr(CO)4{η2‐(Ph2P)2N}K(THF)3]n (2a) and [W(CO)4{η2‐(Ph2P)2N}K(THF)2]n (2b), respectively, in almost quantitative yields. The ionic compounds 2a,b are stable at room temperature. All four compounds 1a,b and 2a,b were characterised by single‐crystal X‐ray diffraction. Compounds 2a,b form infinite chains via isocarbonyl bridges in the solid state. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Hydrothermal Synthesis and Characterization of a Novel Sinusoidal Layer Structure Constructed From Polyoxometalates and Coordination Complex Fragments
Authors: Cui Xiao‐Bing , Xu Ji‐Qing , Li Yong , Sun Ying‐Hua , Yang Guo‐Yu 
Published: March 2004

AbstractA novel polyoxometalate compound, [As8V14O42(SO4)][Ni(en)2]3·4.5H2O (1), has been synthesized by a hydrothermal method and characterized by X‐ray crystallography, showing that the compound 1 is the first example of a sinusoidal layer structure constructed from polyoxometalates and coordination complex fragments. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Preparation and Characterization of Cu2SnSe4 Nanoparticles Using a Microwave‐Assisted Polyol Method
Authors: Grisaru Haviv , Pol V. G. , Gedanken Aharon , Nowik Israel 
Published: March 2004

AbstractThe microwave‐assisted polyol method has been applied to the preparation of nanosized Cu2SnSe4. Cheap materials such as CuCl (or CuCl2·2H2O), Sn and Se were used as starting materials. Polyethylene glycol (PEG) is the only solvent in which the reaction takes place and the materials did not react in ethylene glycol, tri‐, or tetraethylene glycol. Mössbauer spectroscopic measurements revealed a single doublet whose isomer shift of 1.81 mm/s is typical of that seen in tetravalent covalent tin semiconductors. The final product was characterized by X‐ray powder diffraction, transmission electron microscopy (TEM), high resolution TEM (HR‐TEM), scanning electron microscopy (SEM), X‐ray photoelectron spectroscopy (XPS) and electron paramagnetic resonance (EPR) spectroscopy. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Funnel Complexes with CoII and NiII: New Probes into the Biomimetic Coordination Ability of the Calix[6]arene‐Based Tris(imidazole) System
Authors: Sénèque Olivier , Campion Morgane , Giorgi Michel , Le Mest Yves , Reinaud Olivia 
Published: March 2004

AbstractThe coordination properties of the calix[6]arene‐based tris(imidazole) ligand X6Me3Imme3 were further explored with CoII and NiII. This imidazole system stabilizes tetrahedral mononuclear CoII complexes with an exchangeable fourth exogenous ligand (water, alcohol, amide) located at the heart of the hydrophobic calixarene cavity. With a weak donor ligand such as a nitrile, both four‐coordinate tetrahedral and five‐coordinate trigonal bipyramidal complexes were obtained. The latter contains a second nitrile molecule trans to the included guest nitrile. These complexes were characterized in solution as well as in the solid state. The NiII complexes are square‐based pyramidal five‐coordinate edifices with a guest nitrile inside the cavity and a water molecule outside. A comparison with previously described ZnII and CuII complexes emphasizes the flexibility of this ligand. A comparison with carbonic anhydrase, a mononuclear zinc enzyme with a tris(histidine) coordination core, shows that X6Me3Imme3 displays many structural features of this enzyme except for the cis coordination of the exogenous ligands. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Deprotonation of μ3‐Methylidyne Groups on a Ti3O3 Support: A Way to Build Oxotitanocubanes Containing Alkali and Alkaline‐Earth Metals
Authors: Martín Avelino , Mena Miguel , Morales‐Varela María del Carmen , Santamaría Cristina 
Published: March 2004

AbstractThe μ3‐methylidyne group of the complex [{TiCp*(µ‐O)}3(µ3‐CH)] (1) (Cp* = η5‐C5Me5) was deprotonated by amides of the group 1 elements, [MN(SiMe3)2] (M = Li, Na, K, Rb, Cs) to form the oxoheterometallocubane complexes [M(μ3‐O)3{Ti3Cp*3(μ3‐C)}] [M = Li (3), Na (4), K (5), Rb (6), Cs (7)]. Similar treatments of 1 with the alkaline‐earth amides [M{N(SiMe3)2}2(thf)2] (M = Mg, Ca, Sr) afforded the heterometallocubane derivatives [{(thf)x(Me3Si)2NM}(μ3‐O)3{Ti3Cp*3(μ3‐C)}] [M = Mg, x = 0, (8); Ca, x = 1, (9); Sr, x = 1, (10)] in high yields. The addition of ligands such as cyclopentadiene (C5H6) or pentamethylcyclopentadiene (C5Me5H) to the compounds 3−7 allowed recovery of the μ3‐methylidyne oxocomplex 1. The analogous reaction of 8−10 with C5H6 caused the displacement of the amide fragment to give the heterometallocubanes [(CpM)(μ3‐O)3{Ti3Cp*3(μ3‐C)}] [M = Mg (11), Ca (12), Sr (13)], while C5Me5H reacts only with 9 and 10 to give the compounds [(Cp*M)(μ3‐O)3{Ti3Cp*3(μ3‐C)}] [M = Ca (14), Sr (15)]. Furthermore, heating of the species 8−10 in the presence of the starting complex 1 produced amine elimination and afforded the corner‐shared heterometallodicubanes [M{(μ3‐O)3Ti3Cp*3(μ3‐C)}2] [M = Mg (16), Ca (17), Sr (18)]. Treatment of 1 with the amide [Ba{N(SiMe3)2}2(thf)2] or dialkyl derivatives of magnesium [MgR2(thf)2] (R = CH2Ph, tBu) and barium [Ba(CH2Ph)2] provided the corner‐shared metallodicubanes [M{(μ3‐O)3Ti3Cp*3(μ3‐C)}2] [M = Mg(16), Ba(19)]. The molecular structures of complexes 9, 16, 17 and 18 have been established by single‐crystal X‐ray analyses. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
A Molecular Tool for Measuring the Electron‐Acceptor Ability of Ligands from Crystallographic Data
Authors: Fanizzi Francesco P. , Margiotta Nicola , Lanfranchi Maurizio , Tiripicchio Antonio , Pacchioni Gianfranco , Natile Giovanni 
Published: March 2004

AbstractA method is proposed for the direct measurement of the π‐acidity of ligands coordinated to a metal center. The four‐coordinate complex [PtI2(Me2‐phen)] (Me2‐phen = 2,9‐dimethyl‐1,10‐phenanthroline) is unique since it behaves as a molecular trap and, in the presence of a nucleophile (L), one end of it dissociates to allow the L ligand to coordinate trans to the monocoordinated diamine. The coordination of the free end of the phenanthroline is impeded by the filled d orbitals of the metal lying in the same plane as the phenanthroline (dyz and d electrons assuming as x‐axis that of the I−Pt−I vector). However, if the L ligand is a π‐acid able to remove electron charge from the yz plane, the second end of the phenanthroline will also be able to interact with platinum. A linear correlation is found between the crystallographic N−Pt−L angle (180° in ideal square‐planar species and 143° in a trigonal bipyramid with a bite angle for bidentate Me2‐phen of 74°) and the π‐acceptor capacity of the L ligand as estimated by ab initio calculations. Alkenes and alkynes are found to be among the best π‐acids and lead to a regular trigonal‐bipyramidal five‐coordinate species. CO appears to be only halfway in between the best π‐acceptor ligands and those with smallest π‐acidity. P‐, S‐, and N‐donor ligands follow in that order without significant differences between sulfides and sulfoxides or between aliphatic amines and pyridine. The very small difference between aliphatic amines and pyridine has been confirmed by investigation of the rate of exchange between the two ends for monocoordinated phenanthroline by 1H NMR spectroscopy. The activation energy (ΔG‡) was found to be equal, within the experimental error, for the two types of trans ligands. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004)
Composition and larvicidal activity of essential oils from heartwood of Auxemma glazioviana Taub. (Boraginaceae)
Authors: Costa José G. M. , Pessoa Otília D. L. , Menezes Eveline A. , Santiago Gilvandete M. P. , Lemos Telma L. G. 
Published: March 2004

AbstractThe heartwood of two specimens of Auxemma glazioviana, collected in two localities of the state of Ceará, Brazil, were submitted to hydrodistillation and their essential oils were characterized by GC–MS. The major components found in the essential oils from Cristais were α‐bisabolol (sample I, 46.3; sample II, 53.9%) and α‐cadinol (sample I, 21.1%; sample II, 30.6%), while the essential oils from Quixada were dominated by α‐cadinol (sample III, 37.8%) and cadalene (sample IV, 17.9%). The oils from Cristais (samples I and II) were examined with respect to their larvicidal properties against the larvae of a mosquito (Aedes aegypti) and showed LD50 2.98 ppm and 2.53 ppm, respectively. Copyright © 2004 John Wiley & Sons, Ltd.
Single‐degree of freedom Hermite collocation for multiphase flow and transport in porous media
Authors: Fedele Francesco , McKay Melissa , Pinder George F. , Guarnaccia Joseph F. 
Published: March 2004

AbstractThe classical collocation method using Hermite polynomials is computationally expensive as the dimensionality of the problem increases. Because of the use of a C1‐continuous basis, the method generates two, four and eight unknowns per node for one, two and three‐dimensional problems, respectively. In this paper we propose a numerical strategy to reduce the nodal unknowns to a single degree of freedom at each node. The reduction of the unknowns is due to the use of Lagrangian polynomials to approximate the first‐order derivatives over the minimal compact stencil surrounding each node. For the solvability of the problem the reduction of the number of collocation equations is done by a nodal weighting strategy. We have applied the proposed approach to enhance the efficiency of a collocation‐based multiphase flow and transport simulator. Benchmark cases illustrate the higher performance of the new methodology when compared to classical Hermite collocation. Copyright © 2004 John Wiley & Sons, Ltd.
A classifying procedure for signalling turning points
Authors: Koskinen Lasse , Öller Lars‐Erik 
Published: March 2004

AbstractA Hidden Markov Model (HMM) is used to classify an out‐of‐sample observation vector into either of two regimes. This leads to a procedure for making probability forecasts for changes of regimes in a time series, i.e. for turning points. Instead of estimating past turning points using maximum likelihood, the model is estimated with respect to known past regimes. This makes it possible to perform feature extraction and estimation for different forecasting horizons. The inference aspect is emphasized by including a penalty for a wrong decision in the cost function. The method, here called a ‘Markov Bayesian Classifier (MBC)’, is tested by forecasting turning points in the Swedish and US economies, using leading data. Clear and early turning point signals are obtained, contrasting favourably with earlier HMM studies. Some theoretical arguments for this are given. Copyright © 2004 John Wiley & Sons, Ltd.