bluuebunny/crossref_metadata_2025_split huggingface dataset:
CONFLITOS TERRITORIAIS E PROBLEMAS SOCIOAMBIENTAIS NAS ÁREAS DE CAMPOS INUNDÁVEIS DO MUNICÍPIO DE SÃO JOÃO BATISTA – MARANHÃO
Authors: Ferreira Lana Costa , Farias Filho Marcelino Silva , Ferreira Vitoria Gleyce Sousa 
Published: December 2023

Os conflitos territoriais são originados por um conjunto complexo de lutas que envolvem mais de uma dimensão da realidade. Na Baixada Maranhense, região que agrega 21 municípios do norte do Maranhão, dentre os quais está São João Batista, são registrados inúmeros conflitos territoriais, resultantes das disputas por áreas inundáveis utilizadas para a pesca, pecuária e agricultura. Este artigo objetivou analisar as disputas territoriais e suas causas no Município de São João Batista. A pesquisa constou de observação in loco e da aplicação de 200 entrevistas por meio de questionários em nove povoados em que há disputas territoriais. Os dados obtidos permitiram identificar que atividades principais desenvolvidas no munícipio são pecuária, pesca e agricultura e estas dependem parcialmente dos campos inundáveis, áreas em constante disputas. Os principais conflitos são oriundos de construções de açudes e cercas nos campos inundáveis que "privatizam" espaços outrora de usufruto comum. Na percepção de 48,5% dos entrevistados, a construção dos açudes e cercas, criação dos búfalos e implantação dos diques resultaram e/ou intensificaram a degradação ambiental e os conflitos. A pecuária bovina e bubalina resulta em redução da quantidade e qualidade de pescado, com implicações direta e negativa na renda familiar dos pescadores e das outras pessoas envolvidas na cadeia produtiva. A falta de fiscalização e a percepção de 51,5% dos entrevistados de que não há alterações ambientais significativas na área de pesquisa, demonstra uma forte demanda pela atuação dos órgãos estatais na contenção dos crimes ambientais e na promoção de programa de Educação Ambiental.
Impacto de las acciones ejecutadas en la publicación de artículos científicos en un campus universitario cubano
Authors: De la Cruz Raquel , Jiménez Padilla Tamara , Guevara Reyes Onelia 
Published: December 2023

Impacto das ações realizadas sobre publicação de artigos científicos em um campus universitário cubano
Este artigo aborda a avaliação do impacto das ações do corpo docente nas publicações científicas do Centro Universitario Municipal Cap. Silverio Blanco Núñez de Cabaiguán, Cuba. Apoiado em métodos científicos: análise e síntese, histórica e lógica, hipotética e dedutiva; revisão documental, entrevista em grupo, grupos de discussão, brainstorming, estatística descritiva, dentre alguns resultados, constatou-se que a produção científica é de 25% em bases globais de impacto e 75% em bases regionais; (89,3%) é produto de projetos, extensão universitária e em colaboração com redes acadêmicas. Portanto, a relevância da atividade científica pauta-se pela qualidade e pela sua pertinência no contexto da sua ação, com impacto nos vários setores locais.
Palavras-chave: ciência e inovação tecnológica, publicações científicas.

Impacto de las acciones ejecutadas en la publicación de artículos científicos en un campus universitario cubano
RESUMEN. Se expone la evaluación del impacto de las acciones del claustro en las publicaciones científicas del Campus. Sustentado en métodos científicos: análisis y síntesis, histórico y lógico, hipotético y deductivo; revisión documental, entrevista grupal, grupos de discusión, tormenta de ideas, estadística descriptiva. La producción científica es de 25% en bases de datos de impacto mundial y 75% en bases de datos regionales. El (89,3%) es producto de proyectos, la extensión universitaria y en colaboración con redes académicas. Entonces la relevancia de la actividad científica se encamina a partir de la calidad y su pertinencia en el contexto de su actuación, con impacto en los diver­sos sectores locales.
Palabras clave: ciencia e innovación tecnológica, publicaciones científicas.

Impacts of actions executed in the scientific paper publications at Cuban university campus
ABSTRACT. It is expose the evaluation of docent group actions impact to the Scientifics publications at Campus. Fundament in Scientifics methods: analysis and synthesis, historical and logical, hypothetic and deductive; documental revision, interview of group, discussion of groups, torment of ideas, descriptive statistical. The scientific production is 25% in data bases of world impact and75% in data bases regionals. El (89, 3%) is product of projects, the university extension and in collaboration with academics networks. Then the relevance of la activity scientific is enhancing starting of the quality and so pertinence in the actuation context, con impact in diverse locals sectors.
Keywords: science and technological innovation, scientific publications.
Mengenali perspektif historis dan modern accounting
Authors: Urip Wardoyo Dwi , Taris Citra Rahadiansyah Denna , Shofhah Ayuningtias Naura , Anggraeni Rahmadiah Deva , Audia Putri Stefany 
Published: December 2023

Historical and modern perspectives in the field of accounting reflect developments and changes in the way we understand, use and organize financial information over the centuries.This study aims to find out how the development of accounting either from history and modern. The method used is the literatur review. The history of accounting begins with the existence of trade which is growing day by day so that better and more organized records are needed until the Paciolis’s Ledger appear, then in the 19th century double entry accounting has developed a lot. In the 20th century recording began using computer and when the world recession, modern accounting and accounting principles using the double entry aplicaton which lightened the workload of the finance department. Modern accounting was created because of old accounting, meaning that the two synergize and perfect each other until an effective and efficient accounting system is formed.
Transglutaminase 3 regulates cutaneous squamous carcinoma differentiation and inhibits progression via PI3K-AKT signaling pathway-mediated Keratin 14 degradation
Authors: Zhang Xue , Zhou Kaili , Wu Chenglong , Cao Yu , Cheng Wenjie , Zhang Boyuan , Wei Ruoqu , Cheng Daian , Zhang Wenqing , Yao Zhi 
Published: December 2023

Abstract
Background Cutaneous squamous carcinoma (cSCC) is the second most common epithelial malignancy, associated with significant morbidity, mortality, and economic burden. However, the mechanisms underlying cSCC remain poorly understood. In this study, we identified Transglutaminase 3 (TGM3) as a novel tumor suppressor that acts via the PI3K-AKT axis.Methods Real-time reverse transcription-quantitative polymerase chain reaction (RT-qPCR), immunohistochemistry (IHC), and western blotting were employed to assess TGM3 levels. TGM3-overexpression/knockdown cSCC cell lines were utilized to detect TGM3's impact on epithelial differentiation as well as tumor cell proliferation, migration, and invasion in vitro. Additionally, subcutaneous xenograft tumor models were employed to examine the effect of TGM3 knockdown on tumor growth in vivo. Finally, molecular and biochemical approaches were employed to gain insight into the tumor-suppressing mechanisms of TGM3.Results TGM3 expression was increased in well-differentiated cSCC tumors, whereas it was decreased in poor-differentiated cSCC tumors. Loss of TGM3 is associated with poor differentiation and a high recurrence rate in patients with cSCC. TGM3 exhibited tumor-suppressing activity by regulating cell proliferation, migration, and invasion both in vitro and in vivo. As a novel tumor differentiation marker, TGM3 expression was positively correlated with cell differentiation. In addition, our results demonstrated an interaction between TGM3 and KRT14 that aids in the degradation of KRT14. TGM3 deficiency disrupts keratinocytes differentiation, and ultimately leads to tumorigenesis. Furthermore, RNA-sequence analysis revealed that loss of TGM3 enhanced epithelial-mesenchymal transition (EMT) via the PI3K-AKT signaling pathway. Deguelin, a PI3K-AKT inhibitor, blocked cSCC tumor growth induced by TGM3 knockdown in vivo.Conclusion Taken together, TGM3 inhibits cSCC tumor growth via PI3K-AKT signaling, which could also serve as a tumor differentiation marker and a potential therapeutic target for cSCC.
Speech Connectedness Predicts Reading Performance Three Months in Advance: A Longitudinal Experiment
Authors: Mota Natália , Malcorra Bárbara , Ribeiro Marina , Jensen Luísa , Gomes Giovana , Meletti Tamara 
Published: December 2023

Abstract

Aiming to verify the predictive value of oral narrative structure on reading acquisition, we followed 253 children (first and second graders) during an entire school year, assessing oral narratives and reading performances in five sessions. Transcriptions of oral narratives were represented as word-recurrence graphs to measure connectedness attributes. Connectedness predicted performance in phonological awareness, reading comprehension, and word reading accuracy 3–4 months in advance.
Stoichiometric Effect on Defect States and Optical Properties of LiInSe 2 Single Crystals
Authors: Zheng Zhi , Zhu Meng hua , Zhang Zheren , Gao Zhihui , Xu Meng , Zhang Rui , Xu Yadong 
Published: December 2023

Abstract

LiInSe2 crystals are promising semiconductor materials for neutron detector due to the large neutron capture cross-section area of specific isotopes (6Li) and high charge transport properties. However, the optoelectronic performance fails to reach the expected level due to the difficulty of controlling the crystal defects. Herein, we modulate the stoichiometric ratio to control the type of defects in the LiInSe2 single crystals grown by vertical Bridgman method. The UV-vis-NIR transmission results indicate that the band gap of Li1.01In1Se2 sample in yellow color is close to ~ 2.83 eV at room temperature, which is consistent with the theoretical LiInSe2 (~ 2.86 eV). The photoluminescence (PL) spectroscopy is employed to analyze the defect concentration. The results indicate that the defects type in yellow Li1.01In1Se2 single crystal are defined as VSe+ and LiIn2− which results from the introduced excess Li and the suppressed adverse defects of InLi2+ and VLi−. These results demonstrate a feasible route to obtaining yellow high-quality 6LiInSe2 crystals and promote the application of 6LiInSe2 neutron detectors.
Dexmedetomidine attenuates neuroinflammation-mediated hippocampal neurogenesis impairment in sepsis-associated encephalopathy mice through central α2A-adrenoceptor
Authors: Guo Yao-Yi , Zhang Xinlong , Dai Yu-Qi , Zhong Yi , Feng Yue , Jiang Fan , Xing Yan , Shi Hong-Wei , Bao Hong-Guang , Si Yan-Na 
Published: December 2023

Abstract
Sepsis-associated encephalopathy (SAE), one of the common complications of sepsis, is associated with higher ICU mortality, prolonged hospitalization and long-term cognitive decline. Sepsis can induce neuroinflammation, which negatively affects hippocampal neurogenesis. Dexmedetomidine has been shown to protect against SAE. However, the potential mechanism remains unclear. In this study, we added lipopolysaccharide (LPS)-stimulated astrocytes-conditioned media (LPS-CM) to neural stem cells (NSCs) culture, which were pretreated with dexmedetomidine in the presence or absence of the α2-adrenoceptor antagonist yohimbine or the α2A-adrenoceptor antagonist BRL-44408. LPS-CM impaired the neurogenesis of NSCs, characterized by decreased proliferation, enhanced gliogenesis and declined viability. Dexmedetomidine alleviated LPS-CM-induced impairments of neurogenesis in a dose-dependent manner. Yohimbine, as well as BRL-44408, reversed the effects of dexmedetomidine. We established a mouse model of SAE by cecal ligation and perforation (CLP). CLP induced astrocyte-related neuroinflammation and hippocampal neurogenesis deficits, companied with learning and memory decline, which was reversed by dexmedetomidine. The effect of dexmedetomidine was blocked by BRL-44408. Collectively, our findings support the conclusion that dexmedetomidine can protect against SAE, likely mediated by the combination of inhibiting neuroinflammation via astrocytic α2A-adrenoceptor with attenuating neuroinflammation-induced hippocampal neurogenesis deficits via NSCs α2A-adrenoceptor.
Histological description of new specialized reproductive structures in Atlantic dendrophylliid corals (Anthozoa, Scleractinia)
Authors: Zanetti Luca , Dourado Fernanda Santana , Santos Dalton dos , Divino André Amor , Nepomuceno Thalia , Alcantara Joseane , de Oliveira Alisson Carvalho , Farias Amilcar , Silva Aurea Helena Alves , Silva José Rogerio , Johnsson Rodrigo , Neves Elizabeth Gerardo 
Published: December 2023

Abstract
The family Dendrophylliidae comprises a genus of exotic azooxanthellate corals, Tubastraea (the ‘sun corals’), native from the Indo-Pacific and introduced in the Atlantic Ocean in the early 40s. In the Southwestern Atlantic, Tubastraea colonies were first registered in oil platforms on the northern coast of Rio de Janeiro State (22°S). Three decades later, the sun corals were for the first time identified in the Todos-os-Santos Bay (Bahia State, 13°S), a warmer environment with pristine marine ecosystems, such as estuaries, mangroves, and coral reefs. Regarding Brazilian native corals, studies on reproductive biology were developed for the broadcast spawner genera Madracis, Montastraea, and Mussismilia, as well as for the brooder corals Astrangia, Favia, Porites, Scolymia, and Siderastrea. Intending to describe the biological cycle of exotic dendrophylliids from the Brazilian northeastern coast, histological analyses revealed the occurrence of three new reproductive structures never yet observed in Scleractinia. The trophonema is commonly found among actiniarians and has also been registered for antipatharians, zoanthids, and coenothecalians (Alcyonaria). Similarly, an envelope of glycoproteic matter surrounding immature oocytes has never been mentioned for hard corals. Finally, the nucleolinus was thought to be restricted to mollusks and vertebrates, being an indicator of fertilized or parthenogenetic eggs. For the first time, the trophonema, the glycoproteic sac, and the nucleolinus are identified and described for Scleractinia. Beyond unexpected adaptative trends in the reproduction of the sun corals, these unprecedented results consolidate the knowledge about the anatomy and biology of basal metazoans.
Unveiling Pathogenesis and Therapeutic Targets of Metastatic Breast Cancer Through Sparse Modelling of Genomic Landscape
Authors: Zhang Yingsheng , Pu Mengchen , tian kai , zheng weisheng , li xiaorong , fan keyue , zheng liang , zhou jielong 
Published: December 2023

Abstract

Breast cancer is a heterogeneous disease and ranks as one of the most lethal and frequently detected disease in the world. It poses significant challenges for precision therapy. To better decipher the patterns of heterogeneous nature in human genome and converge them into common functionalities, mutational signatures are introduced to define the types of DNA damage, repair and replicative mechanisms shaping the genomic landscape of each cancer patient. In this study, we developed an upgraded deep learning (DL) model, based on pruning technology to improve model generalization through deep sparsity. We applied it to patient whole genome sequencing (WGS) samples, and identified statistically significant mutational signatures associated with metastatic progression using Shapley additive explanations (SHAP). We also employed gene cumulative contribution abundance analysis to link the mutational signatures with relevant genes uncovering the shared molecular mechanisms behind tumorigenesis and metastasis of each patient and potentially lead to novel therapeutic target identification. Our study illustrates that our approach is an effective tool for discovering clinically meaningful mutational signatures in metastatic breast cancer (MBC) and relating them directly to relevant biological functions and gene targets. These findings could facilitate the development of novel therapeutic strategies and improve the clinical outcomes for individual patients.
Probiotic characterization of Bacillus sp. strains from fermented palm wine and investigation of cellulolytic potential in regards to application as animal feed additive
Authors: Borah Munmi , Mandal Manabendra 
Published: December 2023

Abstract

The main objective of this study was to assess cellulolytic probiotic strains from traditional fermented beverages such as palm wine in order to supplement the animal feed and strengthen the gut health of the animal for better digestibility and absorption. In the present study, different types of microbes were isolated from traditionally prepared palm wine and analyzed for their probiotic nature. For any microbe to be probiotic in nature, it has to sustain the harsh conditions of human gastrointestinal tract such as acid tolerance, bile tolerance at lower range of pH and other properties like auto aggregation test, cell surface hydrophobicity test with non-polar hydrocarbons for evaluating its capabilities to adhere to the intestinal cells and antimicrobial nature against pathogens. Bacillus mycoides strain PR04 and Bacillus subtilis strain PR21 were found to be resistant to acid and bile in simulated artificial gastrointestinal tract model, found to be greater than 55% hydrophobic with xylene and n-hexadecane and also showed antimicrobial activity towards pathogenic strains like Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans and Salmonella typhimurium respectively. The cellulolytic activity of the isolates PR04 and PR21 was evaluated in (0.2-2) % CMC (carboxymethyl cellulose) plate. Bacillus mycoides PR04 and Bacillus subtilisPR21 could degrade carboxymethyl cellulose, filter paper and sugarcane bagasse. The degradation of sugarcane bagasse was confirmed by Scanning electron microscopy and filter paper degradation after 4 days of incubation at 37°C. Cellulase gene of the identified Bacillussp. strains was amplified by primers CF5’-‘ACAGGATCCGATGAAAACGGTCAATTTCTATTTT-3’and CR5’-ACTCTCGAGATTGGGTTCTGTTCCCAAT-3’. This study proposes potential probiotic Bacillus mycoides PR04 (Accession no. OR625070) and Bacillus subtilis PR21 (Accession no.OR625072) in application as animal feed additive to assist in its digestibility and encourage the gut health.
Measuring source control efficacy of different fitted masks for sub-micron aerosols
Authors: Pieris Supun , Leung Rachel , Peterson Sean D. , Yarusevych Serhiy , Duriseti Ram 
Published: December 2023

Abstract
SARS-CoV-2, as with other mucosal respiratory viruses, can be spread by both respiratory droplets and aerosols. We examined the filtration efficiency of fitted surgical, KN95, and N95 masks as source control for particle sizes in the 0.2 to 1 micron range. Barrier methods with higher filtration efficacy demonstrated greater filtration of sub-micron particles. However, once steady state was reached, the filtration efficacy was equivalent across the entire spectrum of sub-micron particle sizes tested. Aided by flow visualization, the analysis of the results show that the mask efficiency is driven by leakages despite “pinching” of a high quality form at the nose.
Overexpression ZNF281 facilitates cervical cancer cells invasion by promoting epithelial-mesenchymal transition without affecting proliferation
Authors: Chong Ye , Zhang Kun , Zeng Yuting , Chen Qian , Feng Qian , Cui Nan , Ruan Litao , Zheng Pengsheng 
Published: December 2023

Abstract
Background
Zinc finger transcription factor ZNF281 was first named GC-box-binding zinc-finger protein. Relevant studies have confirmed that ZNF281 protein is involved in the process of cell proliferation, cell apoptosis, cell differentiation and tumorigenesis. However, the function of ZNF281 in cervical cancer remains unknown.
Methods
Both IHC and western blot assays demonstrated that the expression of ZNF281 protein in cervical cancer tissue was much higher than that in normal cervical tissue. ZNF281 was also expressed in human cervical carcinoma cell lines of HeLa, SiHa, C-33 A, CaSki and HT-3. Immunocytochemistry results showed that ZNF281 protein expresses both in the cell nucleus and cytoplasm.
Results
ZNF281 overexpression didn’t affect HeLa cells proliferation and tumor size in situ according to xenograft experiments in nude mice. However, trans-well experiments indicated ZNF281 overexpression facilitated migration and invasion. More tumor lesions were found in the lungs of the nude mice injected with ZNF281 overexpression cell lines than mice injected with control lines.
Conclusion
All these results suggest ZNF281 promoted tumor metastasis without affecting cell proliferation.
The impact of adult patient communication experiences on patient satisfaction with nursing cancer care: A cross-sectional study
Authors: Alshammari Mukhlid 
Published: December 2023

Abstract

Background Patient satisfaction in cancer care can be influenced by several factors including patient communication experiences with nurses. Therefore, understanding patient satisfaction is important in order to improve the quality of nursing care. This study aimed to measure the impact of patient characteristics and communication experiences on patient satisfaction with nursing cancer care.Methods Convenience sampling was used to recruit participants receiving cancer care in Saudi Arabia. Two validated instruments were used to measure patient communication experiences (PCC-36) and patient satisfaction (SNQ-10) with cancer care. The PCC-36 consisted of 36 items subdivided into six domains measuring patient communication experiences, and the SNQ consisted of ten items measuring patient satisfaction with nursing care. We performed descriptive and inferential statistics to analyse the data. A stepwise linear regression model was used to identify the significant predictors of patient satisfaction with cancer care.Results In total, 318 completed and returned surveys. Overall, participants reported good to high satisfaction with nursing care. We found that patient communication experiences regarding exchanging information with nurses, fostering healing relationships, and enabling patient self-management were significant predictors of patient satisfaction. Furthermore, patients with known communication issues relating to aphasia were less satisfied with nursing care. There was no relationship between patient satisfaction and the PCC-36 domains of response to emotions, decisions making, and managing uncertainty.Conclusions During cancer care in Saudi Arabia, exchanging information, fostering healing relationships and enabling patient self-management, all improve patient satisfaction with nursing. There is a need for qualitative research to explore more deeply the association between communication and patient satisfaction in cancer care settings in Saudi Arabia.Practice Implications: Understanding the predictors of patient satisfaction can potentially inform interventions to reduce disparities in the quality of communication. This would improve the care provided by healthcare providers, which would improve the patient’s experiences.