bluuebunny/crossref_metadata_2025_split huggingface dataset:
RIRISK FACTORS OF OCCIPITAL STROKE IN A TERTIARY EYE CENTER IN YOGYAKARTA, INDONESIA
Authors: Satyawati Budhi Hartiwi , Hartono Hartono , Mahayana Indra Tri 
Published: February 2024

Introduction: Occipital stroke involves the occipital lobe of the brain, which can impair the visual acuity in patients. Several risk factors have been proven as predisposing conditions for occipital stroke. This study investigates the risk factors for occipital stroke in tertiary eye center in Yogyakarta.
Methods: The method of this study was cross-sectional research by analyzing secondary data from medical records of patients with occipital stroke hospitalized in Dr. Yap Eye Hospital, a tertiary eye center in Yogyakarta. Patients diagnosed with occipital stroke from January 2021 to December 2022 were included in this study. Demography, clinical data, and risk factors associated with occipital stroke were recorded. The descriptive statistic was performed to evaluate the risk factors for occipital stroke.
Results: Sixty-one subjects were analyzed, comprised of 44 males (72%) and 17 females (28%). The majority of subjects within age ?45 years old (93%). The attack occurred during activity (n=54, 89%) and wake-up (n=7, 11%). The involvement right eye (n=8, 13%), left eye (n=9, 15%), and bilateral (n=44, 72%). Of 122 eyes, 74 had hemianopia (61%), 34 had quadranopia (28%), and 14 had bilateral hemianopia (11%). Twenty-nine subjects had right occipital stroke (48%), 25 subjects had left occipital stroke (41%), and seven subjects had bilateral occipital stroke (11%). Most subjects had one risk factor (n=29, 48%) and two risk factors (n=23, 38%). Eight subjects had three risk factors (13%), and only one subject had four risk factors (2%).
Conclusion: Most risk factors of occipital stroke involve only single and double risk factors. Only a minority of subjects had multiple risk factors.
THE EFFECT OF LIMBAL RELAXING INCISIONS ON 1-WEEK POSTOPERATIVE IN K1 AND K2 VALUES
Authors: Bakhri Ilham Prayoga , Sadasih Wisnu , Fanany A. Rizal 
Published: February 2024

Introduction: Limbal Relaxing Incisions (LRI) is a surgical technique used to correct astigmatism during cataract surgery. This technique used to reduce the steepness of the corneal curvature in a particular meridian. LRI can be performed alone or in combination with phacoemulsification.
Methods: This prospective study aimed to investigate the effect of Limbal Relaxing Incisions (LRI) on corneal astigmatism in patients who underwent phacoemulsification cataract surgery. Five patients were included in this study, and preoperative and 1-week postoperative keratometry values (K1=flat keratometry and K2=steep keratometry) were measured using the IOL Master. Paired t-test analysis was used to compare the changes in K1 and K2 values before and after LRI.
Results: Five patients with the mean age 39.8 years (range: 22 to 76 years) and corneal astigmatism 3.12 D (range: 2.25 to 4.66 D) were underwent LRI and cataract surgery. The mean preoperative K1 and K2 values were 42.12 D and 46.44 D, respectively, while the mean 1-week postoperative K1 and K2 values were 42.60 D and 45.80 D, respectively. Paired t-test analysis showed a statistically significant decrease in K2 values (p = 0.025) but no significant change in K1 values (p = 0.329).
Conclusion: This study showed there were no significant difference between pre and postoperative of K1 and showed a significant decrease in K2 on IOL Master examination. The wide age range of the included patients may have influenced the effectiveness of LRI in reducing astigmatism. Further study with more subjects are required.
OVERVIEW OF OCULAR TOXOPLASMOSIS IN DR KARIADI HOSPITAL SEMARANG
Authors: Ariska Amalia Dwi , Reki Winarto , Novita Dina 
Published: February 2024

Introduction: Ocular toxoplasmosis is the most common infectious etiology of posterior uveitis. The aim of this study is to describe the clinical characteristics of ocular toxoplasmosis in Dr. Kariadi Hospital, Semarang.
Methods: A retrospective review of out-patient medical records of ocular toxoplasmosis at Dr. Kariadi Hospital Semarang from January 2018 to December 2022 was done. All toxoplasmic uveitis were included, whereas incomplete medical records and loss of follow-up were excluded. The clinical characteristics of patients were recorded and analyzed.
Results: During 5 years a total of 160 patients were recruited of which 123 fulfilled the criteria, consisting of 47 males (38.2%) and 76 females (61.8%), mostly were acquired infection (97.6%) with immunocompetent status (75.6%), and affected unilateral eye (65%). The predominant age was 26-45 years old (41.5%). Primary infection (70.7%) was greater than recurrent infection (8.9%) in which recurrence affects 46-65 years old (72.7%). Visual acuity at the initial presentation was <6/18-6/60 (26.2%), and the final follow-up increased to ?6/18 (33.1%). Posterior uveitis (35.1%) with posterior pole lesion (66%) was a common clinical sign found. Medications given were trimethoprim-sulfamethoxazole (51,3%), and corticosteroid (27.5%) as an adjuvant. The complication detected was cataract (13%).
Conclusion: Ocular toxoplasmosis was mostly found in immunocompetent male patients, acquired, unilateral, and in the posterior pole. A good response was found by trimethoprim-sulfamethoxazole and corticosteroid medications.
METHOTREXATE FOR REBOUND PHENOMENON OF VOGT-KOYANAGI-HARADA IN JUVENILE: A RARE CASE REPORT
Authors: Bachmid Humairah , Eka Hasnah , Anoez Azizah , Fikri Bahrul 
Published: February 2024

Introduction: Vogt-Koyanagi-Harada (VKH), an auto-immune disorder driven by melanocyte antigen, is rare in children. The mainstay treatments are corticosteroid and immunomodulators. Methotrexate is one of immunomodulator that widely used due to its effectiveness with minimal side effects.
Case Report: A 9-years-old boy get diagnosed Vogt-Koyanagi-Harada. His best corrected visual acuities (BCVA) were 20/400 in both eyes. Anterior segment examination showed granulomatous uveitis. Posterior segment examination revealed optic disk swelling, Dallen Fuch’s nodule and exudative retinal detachment. We also found poliosis and vitiligo in his lips. He had been previously treated with topical corticosteroids, oral corticosteroids and topical cycloplegics. The dose was tapered every month. After taking medication for 5 months with the last dose oral corticosteroid 16 mg/day and topical corticosteroid every 8 hours, his BCVA recovered to 20/25 RE and 20/40 LE. During the treatment time, the patient discontinued the medication due to parental disobedience and then came with decrease of vision. Based on the consideration of rebound phenomenon and the use of maximum dose of corticosteroids, we consulted the patient to the pediatrician, and decided to give methotrexate as an immunosuppressant. After receiving 15 mg/week of methotrexate for 3 months, inflammation calmed down but unfortunately the vision did not improve.
Discussion: In children, the main treatment for VKH disease is high-dose corticosteroids. Considering the side effects of prolonged systemic corticosteroid therapy, methotrexate become the first line of corticosteroid sparing agent, especially in chronic stage.
Conclusion: Methotrexate can be an effective treatment option for rebound VKH.
Keywords: Juvenile Vogt-Koyanagi-Harada, Steroid Sparing Agents, Rebound Phenomenon, Methotrexate.
SURGICAL OUTCOMES OF STRABISMUS CORRECTION IN LARGE ANGLE EXOTROPIA
Authors: Sadida Rahmah , Ekowati Liana , Saubig Arnila Novitasari 
Published: February 2024

Introduction and Objective: Surgery is one of the treatment options for strabismus. The success rates of surgical interventions, as reported in a number of different studies, vary widely. There is no database of surgical outcome in large angle exotropia patient undergoing surgery in Semarang, Central Java.
This study aims to evaluate the surgical outcome of strabismus correction in large angle exotropia in Dr. Kariadi General Hospital.
Methods: A retrospective study held from the medical record of patients with diagnosis large angle (>50?) exotropia undergoing strabismus correction surgery from January 2020-December 2022 in Dr. Kariadi General Hospital, Semarang. The clinical characteristics: sex, age, angle of exodeviation, amblyopia condition, sensory deprivation, and postoperative alignment were obtained. Surgical outcome measured with follow up of angle deviation in one month dan three months follow up after surgery.
Result: Totally 59 large angle exotropia patients were obtained with 31 (53%) were woman and 28 (47%) were man, range aged 1 year to 53 years old had preoperative angle of exodeviation 51->85 ?, 6 (10%) had amblyopia, 11(18.6%) had sensory deprivation. By the 3 months post-operative visit, 100% of all patients reported orthophoria.
Conclusion: This study found the outcome of strabismus correction for large angle exotropia is satisfactory. Two- or three-muscle surgery provides an effective means for treatment of large angle exotropia.
Keywords: large angle exotropia, exodeviation, strabismus
Characteristics of Patients with Eyelid Laceration in Kariadi General Hospital Semarang
Authors: Padmastrimaya Aderiesta , Erinda Raja 
Published: February 2024

Introduction and Objective: Eyelid laceration is one of the most common ocular injuries with complications. This study examines patient characteristics with eyelid lacerations at Kariadi General Hospital Semarang.
Methods: An observational study used medical records data from April 2019 to January 2023. Age, gender, eyelids, grading, area of laceration, mechanism of trauma and injury, canthal and canalicular involvement, associated injury, and surgery were recorded.
Results: From 75 patients, lacerations were more common in men (56, 75%) and ages 16-<50 years (43, 57%). Lacerations occurred in right lower (21, 28%), right upper (17, 23%), right upper and lower (16, 21%), left lower (9, 12%), left upper (8, 11%), and left upper and lower (4, 5%) eyelids. They were mainly medial (52, 69%), lateral (12, 16%), and central (7, 9%). Full-thickness lacerations (58, 77%) outnumbered lamellar thickness (17, 23%). Blunt trauma (63, 84%) was the main mechanism, with motor vehicle accidents leading 30 (40%). Canthal involvement was absent in 41 cases (55%), medial in 29 (39%), and lateral in 5 (7%). Canalicular involvement was absent in 39 cases (52%) and present in 36 (48%). The three most frequent of associated injury of the patients was 16 (21%) subconjunctival bleeding, 12 (16%) orbital hematom, 9 (12%) conjunctival laceration. All patients underwent surgery, with eyelid repair most common (32, 43%).
Conclusion: Eyelid lacerations mainly involved right lower eyelid, medial region, and are full-thickness. Blunt trauma, particularly motor vehicle accidents, was the main cause. Most cases lack canthal or canalicular involvement. Eyelid repair was the most frequent choice of surgery.
CHEMICAL OCULAR INJURY BY POTASS CHEMICAL OCULAR INJURY BY POTASSIUM PERMANGANAT
Authors: Janardi Saraya Amajida 
Published: February 2024

Introduction: Chemical ocular injury is an emergency case and commonly occured among children. Alkaline chemical ocular injury is more destructive especially due to saponification. One of the rare chemical ocular injury is alkaline trauma by Potassium Permanganate (KMNO4).

Case Report: A case of a three-year-old boy patient brought by his mother in emergency department at Cicendo Eye Hospital with severe pain, redness, and swelling of the left eye. Ten hours earlier, the patient was playing and accidentally exposed to KMNO4. Visual acuity of the right eye was 6/6 and the left eye was difficult to examine. Ophthalmological examination revealed superior and inferior palpebra are swelling, KMNO4 adhered tightly on conjunctival tarsal superior, inferior, and conjunctival bulbi inferior until fornix and temporal area. Cornea was hazed and iris shadow test positive so he was diagnosed with Chemical Trauma Ropper Hall grade II OS. Treatment begins with irrigation 2 litres of normal saline until pH 7 along with debridement of KMNO4 from conjunctival tarsal superior inferior and bulbi. The patient underwent installation of transplanted amniotic membrane and debridement under anasthesia.

Discussion: Management in the initial phase is irrigation. The definitive therapy requires surgery to speed up the healing process. Complications that often occur are corneal limbal cell deficiency, dry eye, symblepharon formation, secondary glaucoma, and complicated cataracts.
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Conclusion: Alkali chemical injury is hazardous and can lead to severe vision threatening complications because of saponification. Prompt and aggressive management is required in such cases to give them the best chance of a more favourable outcome.

Keywords: Chemical ocular injury, Potassium permanganate, Chemical burns, Eye trauma
POTENCY OF OCIMUM SANCTUM L EXTRACT OINTMENT ON THE MANAGEMENT PARTIAL-THICKNESS PALPEBRAL LACERATION, IS IT A NOVELTY TO BE CONSIDERED AS AN ALTERNATIVE THERAPY?: REVIEW ON HISTOPATHOLOGICAL CHANGES IN EXPERIMENTAL MODEL
Authors: Rery Muhammad Insanul Kamil , Lubis Rodiah Rahmawaty , Sitepu Bobby Ramses Erguna 
Published: February 2024

Introduction and Objective:
Ocimum sanctum extract (OSE) has been shown to have antioxidant, anti-inflammatory, and antibacterial properties which are responsible for wound healing. This study aims to analyze the effect of 5%, 10%, and 15% OSE ointment on changes in collagen density and fibroblast count in Wistar rats with partial-thickness palpebral laceration.
Methods:
Laboratory experimental study with randomized post-test only control group design. The subjects were 30 rats divided into 5 groups: The placebo; Gentamicin 0.3%; OSE 5%; OSE 10% and OSE 15% group. The intervention was administered 2 times/day for 4 days. On the fifth day, the palpebral tissue was obtained to make histopathological preparations and to observe the collagen density and fibroblast count. Data were analyzed using Mann-Whitney, One-Way ANOVA, Kruskal Wallis, and Tamhane test. A p-value <0.05 was assigned to the statistically significant.
Results:
The placebo group revealed loose collagen tissue and OSE 15% and gentamicin group revealed dense collagen tissue. The low fibroblast count was in the gentamicin and OSE 15% group and the highest fibroblast count was in the placebo group with a mean of 19.77±3.29; 22,67±0,73 and 60.9±10.66 cells, respectively. There was a significant difference (p<0.001) in the collagen density and the fibroblast count based on the treatment groups. Posthoc tests revealed differences in the collagen density level and the fibroblast count between the placebo and the whole group.
Conclusion:
There was a significant difference between placebo and all groups of collagen density changes and fibroblast count. There was no difference between OSE 15% and gentamicin both microscopically and statistically.

Keywords: Ocimum sanctum L, Extract of Ocimum sanctum L, partial-thickness palpebral laceration, fibroblast cell count, collagen density
Pengaruh Disiplin Kerja, Komitmen Organisasi dan Person Job Fit Terhadap Kinerja Karyawan Pada Sektor Industri Mebel di CV Gardenia Java Ngabul Jepara
Authors: Agustina Sinta , Prawitasari Dian , Oktavia Vicky , Wibowo Mochammad Eric Suryakencana 
Published: February 2024

Perusahaan diharapkan mampu memaksimalkan sumber daya manusia yang terbatas yang dimilikinya guna memenuhi tujuan suatu perusahaan yang telah ditetapkan. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh variabel disiplin kerja, komitmen organisasi, dan person job fit terhadap kinerja karyawan di CV Gardenia Java. Metode penelitian yang digunakan adalah metode kuantitatif. Objek penelitian merupakan salah satu industri mebel yang ada di Jepara. Populasi dalam penelitian ini adalah karyawan pada bagian produksi dengan jumlah 105 orang. Teknik penarikan data yang digunakan adalah kuesioner. Analisis data dengan menggunakan regresi linier berganda dengan bantuan aplikasi SPSS 25. Dalam menganalisis data menggunakan metode statistik dengan menggunakan uji validitas, reliabilitas, dan normalitas. Untuk memastikan apakah data memenuhi asumsi dasar penelitian maka dilakukan uji asumsi klasik. Selain itu peneliti akan melakukan uji multikolinearitas, heteroskedastisitas, uji T, uji simultan (F), dan uji determinasi. Hasil dari penelitian ini menunjukan bahwa: (1) Variabel disiplin kerja mempunyai pengaruh positif terhadap kinerja pegawai yang ditunjukkan dengan nilai b1 (nilai koefisien disiplin kerja) sebesar 0.678 yang artinya semakin meningkat disiplin kerja maka kinerja pegawai akan meningkat; (2) Variabel komitmen organisasi mempunyai pengaruh positif terhadap kepuasan kinerja pegawai, yaitu jika komitmen organisasi meningkat maka kinerja pegawai akan meningkat. Hal ini ditunjukkan dengan nilai koefisien komitmen organisasi (b2) sebesar 0.478; (3) Variabel person job fit mempunyai pengaruh positif terhadap kinerja pegawai yang ditunjukkan dengan nilai koefisien person job fit sebesar 0.561 (b3). Artinya jika person job fit menjadi lebih terjangkau maka kinerja karyawan akan meningkat.
Motivasi Menghafal Al-Qur'an Juz 30 Pada Peserta Didik Kelas VI Dalam Meningkatkan Belajar Baca Al-Qur’an Di Madrasah Ibtidaiah Yamra Merauke
Authors: 'Rudi Hartono  
Published: February 2024

This research aims to determine the process of memorization motivation, motivation factors, and achievement results for class VI students in increasing interest in learning to read the Al-Qur'an through motivation to memorize Al-Qur'an juz 30. This research is classified as a qualitative research type, a research approach that used: phenomenological. The data sources for this research are the Head of the Madrasah, the Head of the Al-Qur'an class coordinator, the Al-Qur'an class supervisor and the students. The data collection methods used were observation, interviews and documentation. Then, data processing and analysis techniques are carried out through three stages, namely: data reduction, data presentation, data verification and drawing conclusions. Research results: A. motivation process for memorizing Al-Qur'an Juz 30: 1) Students' self-awareness of learning, 2) Adjusting goals, 3) Learning to students' needs, 4) Giving a gentle touch, 5) Giving gifts, 6 ) Giving praise and respect, 7) Students knowing their learning achievements, 8) A healthy school environment, 9) Competent and humorous teachers. B. Factors that influence motivation to memorize the Qur'an: a) Internal factors, in the form of attitude, personality, education, experience and ideals. b) External factors, in the form of social and non-social environments. C. Student achievement results: 1) can memorize Juz 30 according to the target, 2) can read the Al-Qur'an well and correctly, and 3) master the science of recitation.
Keywords: Al-Qurán, Motivation, Memorizing
Investigation the Relationship Between Myonectin Levels and Both Lipid Profiles and Liver Function Tests in Diabetic Nephropathy Patients
Authors: Ismail Zahraa. M. , Al-Fartusie Falah S. , Tahir Noor. T. , Ismail Ahmed H. 
Published: February 2024

Myonectin, or CTRP12, is a relatively recent adipokine—a protein released by adipose tissue that has gained interest in the context of metabolic health, including its possible implications in diabetic complications. Volunteers were divided into three groups, healthy subjects as controls (group A), they don't suffer from any disease, patients with T2D without nephropathy (group B) and T2D with nephropathy (group C), the age ranges between (35-70) years and the average duration disease of T2D (5-25) years, attending to the AL-Kindi teaching hospital, Baghdad Iraq. There was a highly significant increase P ≤ 0.01 of FBS, Insulin level, HOMA-IR, HbA1c, TC, TG, HDL and TSB among different groups (T2D with nephropathy, T2D without nephropathy, and control), a highly significant increase P ≤ 0.01 of myonectin levels among different groups. There was no significant difference present in AST U/L, and ALP U/L. A statistically significant increase in ALT U/L when compared with the control group. Conclusion: Levels of serum myonectin were significantly higher in patients with (T2D without nephropathy) as compared with ( T2D with nephropathy) and the control group.
VIGILÂNCIA EM SAÚDE PÚBLICA: ANÁLISE EPIDEMIOLÓGICA DAS ÁGUAS RESIDUAIS, PÓS-COVID-19
Authors: Afonso Cabral Marcos Vinicius , Mesquita de Sousa Amauri , Amaral Tillmann Ingrid Inez , Belém Reis Phamella , Bitencourt e Bitencourt Emanoelen , Sousa Gama Eliege , Dos Santos Benjamin João Vitor , das Neves Martins Fernanda Eduarda , Cardoso Valadares Prestes Marizete do Socorro , Carvalho de Araújo José Augusto 
Published: February 2024

O conceito de epidemiologia em águas residuais do inglês, (Wastewater-Based Epidemiology – WBE) tem potencial para avanços significativos para a saúde pública. Ao identificar biomarcadores em amostras de esgoto, as técnicas de monitoramento de doenças podem ser transformadas, resultando em uma melhor tomada de decisão e na rápida implementação de intervenções de prevenção, controle e tratamento por parte das organizações de saúde. Diante disso, o objetivo desta pesquisa foi identificar e apresenta os benefícios e obstáculos da epidemiologia em águas residuais para o monitoramento de doenças e orientar medidas de vigilância da saúde pública. A metodologia empregada nesta pesquisa envolveu uma análise minuciosa de 10 artigos científicos provenientes das bases de dados, Medline, Scielo, BVS e Pubmed. Os artigos, publicados entre 2019 e 2023, forneceram informações valiosas sobre a importância da realização de análises epidemiológicas de águas residuais e sua correlação com a vigilância sanitária. Como resultado, o estudo mostrou que a análise de biomarcadores encontrados na excreção humana fornece informações valiosas sobre uma variedade de aspectos. Isto inclui estimativas populacionais, a detecção precoce de surtos de doenças infecciosas, como as causadas pelo vírus SARS-CoV-2 (Covid-19), o consumo de medicamentos, a adesão aos tratamentos farmacológicos prescritos, o desenvolvimento de resistência antimicrobiana, a exposição a poluentes e toxinas prejudiciais, a segurança alimentar. e mapeamento da doença na população. Assim, conclui-se que forma rápida e econômica a vida e o bem-estar da população, a incorporação e implementação de procedimentos padronizados e eficientes em vários programas provou ser altamente eficaz. A dependência da vigilância, especialmente nos países em desenvolvimento, é um tema de grande interesse.