bluuebunny/crossref_metadata_2025_split huggingface dataset:
CORRELATIONS OF INDICATORS OF THE IMMUNE SYSTEM, CARBOHYDRATE AND LIPID METABOLISM IN DIABETIC RETINOPATHY IN PATIENTS WITH DECOMPENSATED DIABETES DIABETES
Authors: Gorecha M. Yu. , Demianchuk N. R. 
Published: January 2024

Introduction. Pathogenetic mechanisms of the development of diabetic retinopathy are related to the toxic effect of hyperglycemia on the development of oxidative stress with subsequent activation of stress-sensitive systems
The aim of the study. To find out the presence of correlations in patients with diabetic retinopathy against the background of decompensated diabetes
Research methods. A clinical and laboratory examination of 70 diabetic retinopathy patients with decompensated diabetes mellitus was carried out. In order to identify correlations, the coefficient of linear correlation |r| was determined between all studied indicators
Results and discussion. The analysis of these correlations indicates the formation of a block of strong correlations of peripheral blood leukocytes (except lymphocytes) and natural killers with indicators of lipid metabolism and pro-inflammatory cytokines.
Strong correlations of T-lymphocyte subpopulations with indicators of carbohydrate metabolism and non-atherogenic fraction of lipoproteins were revealed.
In the analysis of the correlations of the B-link of immunity, a positive strong correlation of the relative content of B-lymphocytes (CD19+) with CIC (r = 0.96, p < 0.05) was revealed, which indicates the dependence of the occurrence of type III hypersensitivity reactions with indicators of humoral immunity.
Probable positive correlations of pro-inflammatory cytokines with atherogenic fractions of lipids and glucose, negative correlation of TNF-α with the acute phase marker C-peptide were revealed
Conclusions. When analyzing the correlations of the studied indicators in patients with decompensated diabetes, 13 probable strong positive and 9 probable strong negative correlations were established).
The increase in the pro-inflammatory component is manifested in the correlations of peripheral blood leukocytes (except lymphocytes) and natural killers with indicators of lipid metabolism and pro-inflammatory cytokines, strong correlations of T-lymphocyte subpopulations with indicators of carbohydrate metabolism and the non-atherogenic fraction of lipoproteins, type III hypersensitivity reactions with indicators of humoral immunity , pro-inflammatory cytokines with atherogenic fractions of lipids and glucose, negative relationship of TNF-α with acute phase marker C-peptide
Participación de las familias en los centros de secundaria, de lo institucional a lo transformador
Authors: Hipólito Ruiz Natalia , Martínez Martín Irene , Bejarano Franco María Teresa 
Published: January 2024

Este artículo tiene como objetivo abordar la participación en los centros de educación secundaria en Castilla La-Mancha, específicamente, desde las voces y vivencias de las familias. Se expone, la parte de la investigación referida a la participación de las familias en los centros de secundaria en función del hábitat, respondiendo a las siguientes cuestiones: ¿Qué vivencias tienen las familias en relación con la participación? ¿Cómo definen, las familias, la participación en los centros educativos de secundaria? y ¿Cómo se da el salto de lo teórico a la participación real de las familias en los centros de secundaria?. Para ello, se plantea un análisis descriptivo de los resultados de cuestionarios aplicados con una muestra aleatoria de familias 582 sujetos pertenecientes a familias de 60 centros educativos, siguiendo una metodología integradora. Como resultados, se destaca la importancia de la participación familiar en los centros educativos avalada por la legislación y acorde a las percepciones de las propias familias. Y se pone en cuestión la cultura de la participación, así como las brechas entre la participación formal y la participación real en las comunidades educativas. La propuesta desvela la importancia de crear alianzas entre familias e instituciones de educación secundaria para generar ciudadanía más crítica y proactiva.
Emergência e desenvolvimento da pedagogia social em âmbito escolar: o caso português
Authors: Sousa Neves Vieira Ana María , Vieira Ricardo , Marques José Carlos 
Published: January 2024

Lidar com toda a diversidade que está patente hoje nas escolas contemporâneas implica recorrer a ferramentas da pedagogia social e, particularmente, da mediação intercultural ao serviço da mediação escolar e/ou sociopedagógica. Só desta forma a escola poderá responder à crescente heterogeneidade da sociedade contemporânea que se visibiliza cada vez mais na escola, isto se não se pretender enveredar por atitudes e práticas uniformizadoras e assimilacionistas. Na escola refletem-se muitos dos problemas sociais do mundo de hoje. A escola é, ela própria, parte da realidade social. Consequentemente, muitas das questões que surgem na escola, em consequência do aumento substancial da multiculturalidade dos seus públicos, fogem à função tradicional do professor. É por isso que é importante pensar que o espaço escolar não deverá ser um território exclusivo de professores e alunos, mas que deverá ser também dinamizado e intervencionado com educadores sociais que atuem em vertentes mais socioculturais e sociopedagógicas, que cultivem outro tipo de relacionamento com os alunos, que tenham uma perspetiva diferente das realidades de cada um, e que procurem, fora da escola, também, a compreensão e a ajuda para a resolução desses mesmos problemas. Estes profissionais especializados são fulcrais para que se faça um trabalho de prevenção e de mediação, no sentido de evitar situações que poderiam ser evitadas antes das situações extremadas como sejam o bullying ou a indisciplina na escola. A partir da análise da literatura relevante, o artigo tem como objetivo explorar e comparar a emergência da pedagogia social e da mediação intercultural nas escolas contemporâneas em vários países e, particularmente, em Portugal, como estratégia disciplinar e/ou profissional de educadores socais na promoção da inclusão social, convivência e trabalho em rede entre a escola, famílias e comunidades.
Ocio ambiental en clave intergeneracional. Motivaciones para su práctica
Authors: Alonso Ruiz Rosa Ana , Valdemoros San Emeterio María Ángeles , Martínez Villar José Manuel 
Published: January 2024

El ocio ambiental intergeneracional y, más en concreto, el compartido entre abuelos y abuelas con sus nietos y nietas, aporta numerosos beneficios. Al tratarse de una dimensión del ocio directamente vinculada a la naturaleza y a actividades al aire libre, contribuye a la consecución de distintos objetivos compatibles con el desarrollo sostenible, percibiéndose como una experiencia enriquecedora, atractiva y flexible, que cohesiona y estrecha los vínculos entre generaciones. El propósito de este trabajo fue examinar el ocio ambiental compartido entre abuelos1 y nietos, y las motivaciones vinculadas a dicha práctica. Se combinó metodología cuantitativa (N=350) y cualitativa (N=18), utilizando cuestionario un ad hoc y un grupo de discusión, respectivamente. Los resultados muestran que las actividades de ocio intergeneracional en entornos naturales cada vez son más practicadas; los viajes, así como el cuidado de plantas, huerto y animales son las actividades preferentes. Los motivos preferentes para la realización de estas experiencias compartidas son la transmisión de conocimientos y afecto, y el cuidado que profesan los abuelos y abuelas a sus nietos y nietas. La prospectiva apunta a profundizar si tras la pandemia ha crecido el valor concedido al ocio ambiental, por su potencial para facilitar el contacto intergeneracional en entornos seguros.
Motivations for Pursuing a Career in Podiatric Medicine
Authors: Trinh Kevin C. , Natarajan Rahul V. , Cooperman Steven R. , Shofler David 
Published: January 2024

Background: Although podiatric medicine is a growing field, it is still relatively unknown to many in the general public, including those seeking careers in medicine. The purpose of the present study is to portray the perspectives of current podiatric medical students on motivational factors that encouraged them to pursue the field.
Methods: An online survey was developed and delivered to the student body of a single podiatric medical school. The survey investigated the motivation to pursue podiatric medicine, including first exposure to the field, shadowing experiences, and a variety of motivational factors.
Results: Of 149 students, 81 (54.4%) completed the survey. The three highest-rated reasons for pursuing podiatric medicine were “stable and secure future,” “work-life balance,” and “intellectual satisfaction.” The three most-cited types of first exposure to podiatric medicine were “undergraduate pre-health advisor,” “family member/friend is a podiatrist,” and “form of media other than television, including the Internet.” Shadowing experiences were identified as an important part of developing an interest in pursuing podiatric medicine, especially in the surgical setting.
Conclusions: Understanding the perspectives of current podiatric medical students is important in considering future efforts to promote the profession.
Is Tenderness of Medial Malleolus Circumference a Sign of Syndesmosis Injuries?
Authors: Kasman Ugur Onur , Surucu Serkan , Korkmaz Ozgur 
Published: January 2024

Background: Syndesmosis injuries occur in approximately 10% of all ankle fractures. The integrity of the deltoid ligament is important in the decision of surgical treatment of lateral malleolus fractures.
Methods: Patients who were operated on for Weber B ankle fracture were evaluated retrospectively, and the relationship between tenderness around the medial malleolus and syndesmosis injury was investigated. Patients with visual analog scale, Foot and Ankle Ability Measure daily living, and sports activity scores in their files were included. This study enrolled 38 patients. The patients were divided into two groups. Group 1 consisted of patients with a medial space greater than 4 mm on preoperative radiographs and a positive intraoperative Cotton test, in which a syndesmosis screw was used. Group 2 consisted of patients with a medial space less than 4 mm on preoperative radiographs and negative intraoperative Cotton test, for whom no syndesmosis screw was used.
Results: In 17 of 38 patients, syndesmosis screws were used because of intraopeative positive Cotton test. In 21 patients, the Cotton test was negative and the syndesmosis screw was not used. Comparing the groups statistically revealed no statistically significant difference in all scores. Tenderness around the medial malleolus was detected in two patients in group 2 and nine patients in group 1. A statistically significant difference was detected in terms of medial clear space values and tenderness around the medial malleolus between both groups.
Conclusions: The absence of tenderness around the medial malleolus in Weber B ankle fractures indicates no syndesmosis injury, whereas the presence of tenderness around the medial malleolus does not mean that there is a syndesmosis injury.
Clinical impact of heterogeneously distributed tumor-infiltrating lymphocytes on the prognosis of colorectal cancer
Authors: Liu Lu , Long Meiling , Su Shengyuan , Wang Lijun , Liu Jintao 
Published: January 2024

Background
Tumor-infiltrating lymphocytes (TILs) exist in various malignancies, and have been viewed as a promising biomarker to predict the efficacy and outcome of treatment. However, the marked inter- and intra-tumor heterogeneity of TILs has resulted in some confusion regarding their impact on the prognosis of colorectal cancer (CRC).

Methods
In this study, 78 CRC patients were enrolled and the CD3+ and CD8+ TILs densities at the tumor center (TC), the invasive margin (IM) and the tumor stroma (TS) were assessed by immunohistochemical staining. Their associations with clinicopathological features and progression free survival (PFS) were analyzed to evaluate the predictive and prognostic values of TILs.

Results
TILs were mainly distributed along the invasive margin. High density of TILs in tumor center and invasive margin was associated with smaller tumor size (CD3+TILsIM), reduced tumor invasion (CD3+TILsIM), absence of lymph node metastasis (CD3+TILsIM and CD8+TILsTC), earlier stage (CD3+TILsIM and CD8+TILsIM), and lower tumor grade (CD3+TILsIM and CD8+TILsTC). However, stromal TILs were not associated with any clinicopathological features. Kaplan–Meier survival analysis revealed that high densities of TILs always correlated with prolonged patient survival. The pathological N stage, CD3+ TILsIM and CD8+ TILsTC were found to be independent prognostic indicators. Additionally, early-stage CRC patients who developed recurrence after surgery, showed a higher CD3+/CD8+ TILs ratio in invasive margin. In the present study, it was clarified that CD3+ and CD8+ TILs were heterogeneously distributed in tumor tissues of CRC. The increase in intratumoral and peritumoral TILs had been shown to be strongly predictive of improved clinical outcome. More importantly, the immune signatures enabled to stratify early-stage CRC patients with high risk of recurrence, highlighting the prognostic power of TILs.
An Assessment of the Viability of Haematological and Haemostatic Parameters of Blood under certain Storage Conditions at the Rivers State University Teaching Hospital Blood Bank in Port Harcourt, Nigeria
Authors: Nkabari Nwika Goodnews , Mgbeoma Eze Evelyn , Obioma Azuonwu , Ken-Ezihuo Stella U.  
Published: January 2024

Introduction: Despite significant advances in transfusion medicine, concerns about the inherent risks of blood transfusion persist, even under optimal temperature and duration of storage. This makes the evaluation of blood viability a global task (1). Maintenance of adequate temperature is considered a key factor in the viability and quality of stored blood in healthcare institutions. Evaluating the haematological and haemostatic functionality of blood elements at different storage temperature and duration is therefore imperative for improving patient care and resource utilization in Rivers State University Teaching Hospital (RSUTH) blood bank in Port Harcourt.
Methods: In this cohort study design, a total of sixteen (16) male and female blood donors in equal proportion of sex and ABO blood groups were randomly selected from the Port Harcourt blood donors' population and recruited as study subjects for this research. A well-structured questionnaire and the immunoassays were used to assess the donors' health and serological status respectively. Also the sample obtained were analayzed by automation and data statistically analyzed using ANOVA.
Results: The results of this study shows a statistically significant decrease in white blood cell count from 4.93×109/L ± 0.33 to 2.79×109/L ± 1.68 (p=0.00) and platelet count from 227.38×109/L ± 32.17 to 153.75×109/L ± 58.39 (p=0.00) at day 7. Also, a significant decrease in platelet count from 227.38×109/L ± 32.17 to 141.50±60.92 at day 14. A significant decrease in Fibrinogen from 340.75mg/L±18.69 to 281.2575 mg/L ±46.41 at day 1 and day 14 respectively, and rise in PT and aPTT from 17.02s ±1.28 to 24.31s ±6.67 and 41.25s±3.23 to 46.63s±6.28 at day 14th to day 21 respectively (p=0.00).
Conclusion and Implications for Translation: Pooled plasma at 4-60C contain clinically significant amount of coagulation factors up to day 21 in storage. The WBC and platelet is lost within seven day of storage at 4-60C. Lower temperatures, especially freezing at -60°C accelerate the loss of haematological viability of blood especially the depletion of white blood cells and platelets (p=0.00). Antihaemophilic factor and fibrinogen is maintained in FFP at 180 day in storage at -600C.
An Investigation on the Occurrence of Brinjal Wilt Caused by Sclerotium rolfsii in Northern Karnataka, India
Authors: Kirankumar S. J. , Yadahalli K. B. , Hegde G. M. , Purushotham Pooja 
Published: January 2024

Aims: The Sclerotium wilt of brinjal caused by S. rofsii is an important disease and occurs severely in the brinjal growing areas of northern Karnataka. To gain knowledge about the prevalence of sclerotium wilt of brinjal in different districts of northern Karnataka. And also to study the factors that contribute to the disease occurrence following research was conducted.
Study Design: Roving survey.
Place and Duration of Study: The laboratory studies were conducted in the Department of Plant Pathology, College of Agriculture, University of Agricultural Sciences, Dharwad during rabi 2020-21.
Methodology: A roving survey was conducted in five northern Karnataka brinjal growing districts during rabi 2020-21, observing Sclerotium wilt incidence and calculating percentages. The survey collected data was used to reveal a correlation between disease incidence and soil type, irrigation type, mulch type, and crop stage.
Results: The survey conducted in five districts of northern Karnataka (Belagavi, Bagalkot, Dharwad, Haveri and Gadag) revealed that maximum disease incidence of 35.07 percent was recorded in Narendra village of Dharwad district followed by Nulageri village (17.71%) of Haveri district. No disease incidence was observed in Hanchinal village of Belagavi district and Pettur village of Bagalkot district. The average mean of district for Sclerotium wilt of brinjal was also recorded and results revealed that, Dharwad district showed maximum percent disease incidence (12.39%) followed by Haveri (9.03%), Gadag (7.93%) and the least percent disease incidence (6.89%) was recorded in Bagalkot district.
Conclusion: A study on brinjal sclerotium wilt found that edaphic factors and agronomic practices, such as flooded irrigation and lack of mulching, contribute to high disease incidence in all five districts. Flooding spreads inoculum, while mulching improves soil temperature and restricts sclerotial germination. The fruiting and flowering stages of crops are most susceptible to disease due to nutrient imbalance and S. rolfsii invasion, urging the need for integrated management strategies to reduce brinjal sclerotium wilt.
Effect of Socio-economic Characteristics on Pomegranate Productivity of Farmer Producer Organizations Member Farmers
Authors: Kolekar Pallavi , Chavan R. V. , Bharati S. V. 
Published: January 2024

The Investigation was carried out during 2022 to study the socio-economic status of Farmer producer organizations member farmers. The multistage sampling method was used for selection 26 samples from the Western Region of Maharashtra. The results revealed that, Overall Average age of the farmers was 39.98 years with 8.76 years of experience. The education level of farmer was up to higher secondary i.e.,10.53 years. The average family size was 6.94 number of person with land holding of 3.56 years. Study showed that, the explanatory parameters successfully explained 99.8% of the overall variance in the pomegranate yield, with random errors accounting for the remaining 1%. The findings indicated that age, education, income, and investment all played crucial roles in increasing productivity, while other socio-economic factors including land ownership, experience, and family size did not show significant affect on yield.
Parental Income's Impact on Student Participation in Lesson Activities for Equitable Educational Outcomes
Authors: Careemdeen Jalal Deen 
Published: January 2024

Aims: This study aims to investigate the relationship between parental income and student participation in lesson activities among secondary schoolchildren in Sri Lanka. The primary objectives is identifying potential differences based on parental income levels, and providing valuable insights into the broader implications for educational equity.
Study Design: Employing a survey and quantitative research design, this study gathers data from 1350 secondary school students. The research focuses on diverse aspects of student participation, including group work, discussions with teachers and family, experiments, practical activities, and interactions through social media. A Likert Scale with five response options is utilized to measure student engagement, offering a comprehensive view of their involvement.
Place and Duration of Study: The study is conducted in secondary schools across Sri Lanka. Data collection spans a specified duration, ensuring a representative sample of participants. The diverse geographical and socio-economic landscape of Sri Lanka enriches the study's scope, allowing for a nuanced understanding of the interplay between parental income and student participation.
Methodology: A stratified random sampling technique is employed to select 1350 participants, ensuring a diverse representation of secondary school students. The questionnaire, validated by experts in the sociology of education, comprises two sections: one gathering demographic information and the other assessing students' perceptions of their involvement in lesson activities. Descriptive and inferential statistics, facilitated by the Statistical Package for the Social Sciences (SPSS) Version 23, enable a comprehensive analysis of the data.
Results: Descriptive analysis reveals a moderately high overall level of student participation in various lesson activities. Notably, group activities receive the highest mean value, indicating a strong positive correlation with student engagement. The multivariate analysis of variance (MANOVA) demonstrates significant differences based on parental income levels, with upper-middle-class students exhibiting higher participation than their peers from lower-income backgrounds.
Conclusion: The study concludes by highlighting the crucial role of parental income in shaping students' educational experiences. Findings underscore the disparities in engagement levels, emphasizing the need for targeted interventions and policy initiatives to promote educational equity. Educators, policymakers, and parents are urged to consider these insights to foster a more inclusive and equitable educational system in Sri Lanka.
Spectra of wavelet scale coefficients from process acoustic measurements as input for PLS modelling of pulp quality
Authors: Björk Anders , Danielsson Lars‐Göran 
Published: October 2002

AbstractAcoustic and vibration signals are captured by simple standard accelerometers. These can often be mounted directly on operative process equipment, creating a completely non‐invasive measurement system. The signals from the accelerometer are then amplified, digitized by an analogue‐to‐digital converter and stored in some suitable format in a PC. The method most often used for signal processing of acoustic data has been to apply variants of fast Fourier transform (FFT) on sampled data to produce a frequency domain representation. An alternative way tried here is to use the fast wavelet transform (FWT) in combination with FFT. The FWT has the advantage that it produces time‐resolved representations and, on each time scale, different features can be extracted. However, in this case, time resolution has no meaning, since the starting points for data acquisitions were not fixed. The wavelet step can be seen as a series of pre‐filters and it is here followed by FFT on coefficients at each wavelet scale. The results are compared to those obtained after FFT on the complete time series. We have used spectra of wavelet scale coefficients in an attempt to model pulp quality with PLS. In this case the number of points in the resulting wavelet multiresolution spectrum (WT‐MRS) can be limited to a low number, e.g. 255 compared to 1025 with direct FFT on the time series. In the PLS modelling step the advantage is that the first two components describeYmuch better than when using the conventional approach, e.g. 72% explainedYvariance compared to 40%. A second advantage is that the model requires fewer coefficients. Copyright © 2002 John Wiley & Sons, Ltd.