bluuebunny/crossref_metadata_2025_split huggingface dataset:
Minimizing SONET ADMs in unidirectional WDM rings with grooming ratio 3
Authors: Bermond Jean‐Claude , Ceroi Stephan 
Published: February 2003

AbstractWe consider traffic grooming in WDM unidirectional rings with all‐to‐all uniform unitary traffic. We determine the minimum number of SONET/SDH add–drop multiplexers (ADMs) required when the grooming ratio is 3. In fact, using tools of design theory, we solve the equivalent edge‐partitioning problem: Find a partition of the edges of the complete graph on n vertices (Kn) into subgraphs having at most three edges and in which the total number of vertices has to be minimized. © 2003 Wiley Periodicals, Inc.
Semiempirical local spin: Theory and implementation of the ZILSH method for predicting Heisenberg exchange constants of polynuclear transition metal complexes
Authors: O'Brien Ted A. , Davidson Ernest R. 
Published: February 2003

AbstractThe local spin formalism (Clark, A. E.; Davidson, E. R. J Chem Phys 2001, 115, 7382–7392) for computing expectation values 〈SA· SB〉 that appear in the Heisenberg spin model has been extended to semiempirical single determinant wave functions. An alternative derivation of expectation values in restricted and unrestricted cases is given that takes advantage of the zero differential overlap (ZDO) approximation. A formal connection between single determinant wave functions (which are not in general spin eigenfunctions) and the Heisenberg spin model was established by demonstrating that energies of single determinants that are eigenfunctions of the local spin operators with eigenvalues corresponding to high‐spin radical centers are given by the same Heisenberg coupling constants {JAB} that describe the true spin states of the system. Unrestricted single determinant wave functions for transition metal complexes are good approximations of local spin eigenfunctions when the metaldorbitals are local in character and all unpaired electrons on each metal have the same spin (although spins on different metals might be reversed). Good approximations of the coupling constants can then be extracted from local spin expectation values 〈SA· SB〉 energies of the single determinant wave functions. Once the coupling constants are obtained, diagonalization of the Heisenberg spin Hamiltonian provides predictions of the energies and compositions of the spin states. A computational method is presented for obtaining coupling constants and spin‐state energies in this way for polynuclear transition metal complexes using the intermediate neglect of differential overlap Hamiltonian parameterized for optical spectroscopy (INDO/S) in the ZINDO program. This method is referred to as ZILSH, derived from ZINDO, Davidson's local spin formalism, and the Heisenberg spin model. Coupling constants and spin ground states obtained for 10 iron complexes containing from 2 to 6 metals are found to agree well with experimental results in most cases. In the case of the complex [Fe6O3(OAc)9(OEt)2(bpy)2]+,a prioripredictions of the coupling constants yield a ground‐state spin of zero, in agreement with variable‐temperature magnetization data, and corroborate spin alignments proposed earlier on the basis of structural considerations. This demonstrates the potential of the ZILSH method to aid in understanding magnetic interactions in polynuclear transition metal complexes. © 2003 Wiley Periodicals, Inc. Int J Quantum Chem, 2003
Putative involvement of crustacean hyperglycemic hormone isoforms in the neuroendocrine mediation of osmoregulation in the crayfishAstacus leptodactylus
Authors: Serrano Laetitia , Blanvillain Gaëlle , Soyez Daniel , Charmantier Guy , Grousset Evelyse , Aujoulat Fabien , Spanings-Pierrot Céline 
Published: February 2003

SUMMARYThis study investigates the involvement of eyestalk neuroendocrine factors on osmoregulation in the crayfish Astacus leptodactylus maintained in freshwater. Eyestalk removal was followed by a significant decrease in hemolymph osmolality and Na+ concentration and by a 50% increase in mass after one molting cycle. Several neurohormones have been isolated from the sinus gland through high-performance liquid chromatography (HPLC), and different crustacean hyperglycemic hormone (CHH)-related peptides, including stereoisomers (L-CHH and D-Phe3 CHH), have been identified by direct enzyme-linked immunosorbent assay (ELISA). A glucose quantification bioassay demonstrated a strong hyperglycemic activity following injection of the immunoreactive chromatographic fractions and showed that the D-Phe3 CHH was the most efficient. Destalked crayfish were then injected with purified CHH HPLC fractions. The D-Phe3 CHH fraction significantly increased the hemolymph osmolality and Na+ content 24 h after injection. Two other CHH-related peptides caused a smaller increase in Na+ concentration. No significant variation was observed in hemolymph Cl- concentration following injection of any of the CHH isoforms. These results constitute the first observation of the effects of a CHH isoform, specifically the D-Phe3 CHH, on osmoregulatory parameters in a freshwater crustacean. The effects of eyestalk ablation and CHH injection on osmoregulation and the identification of different CHH-related peptides and isoforms in crustaceans are discussed.
Myogenic cell cycle duration inHarpagiferspecies with sub-Antarctic and Antarctic distributions: evidence for cold compensation
Authors: Brodeur Julie C. , Calvo Jorge , Clarke Andrew , Johnston Ian A. 
Published: February 2003

SUMMARYIn teleosts, the proliferation of myogenic progenitor cells is required for muscle growth and nuclear turnover. We measured the cell cycle and S-phase duration of myogenic cells in the fast myotomal muscle of two closely related Harpagifer species by cumulative S-phase labelling with 5-bromo-2′-deoxyuridine (BrdU). Harpagifer antarcticus is a stenothermal species from the Antarctic peninsula (experiencing temperatures of -2°C to +1°C) and Harpagifer bispinis is a eurythermal species from the Beagle Channel, Tierra del Fuego (living at +4°C in winter and up to 11°C in summer). Specific growth rates in the adult stages studied were not significantly different from zero. Myogenic progenitor cells were identified using an antibody against c-met. Seventy-five percent of the c-met+ve cells were in a proliferative state in both species. Cell cycle time was 150 h at 5°C and 81.3 h at 10°C in H. bispinis (Q10=3.4). Cell cycle duration was 35% shorter in H. antarcticus at 0°C (111 h) than in H. bispinis at 5°C. The predicted cell cycle time for H. bispinis at 0°C(based on the Q10 relationship) was 277 h, which was more than double that measured for the Antarctic species at this temperature. The results obtained are compatible with an evolutionary adjustment of cell cycle time for function at low temperature in the Antarctic species.
Sex Disparities in Ophthalmology From Training Through Practice
Authors: Rousta Nikki , Hussein Isra M. , Kohly Radha P. 
Published: January 2024

ImportanceSex-based research in medicine has revealed inequities against females on almost every metric at almost every career stage; ophthalmology is no exception.ObjectiveTo systematically review the experiences of females in ophthalmology (FiO) from training through practice in high-income countries (HICs).Evidence ReviewA systematic review of English-language studies, published between January 1990 and May 2022, relating to FiO in HICs was performed. PubMed, MEDLINE, and Embase electronic databases were searched, as well as the Journal of Academic Ophthalmology as it was not indexed in the searched databases. Studies were organized by theme at each career stage, starting in medical school when an interest in ophthalmology is expressed, and extending up to retirement.FindingsA total of 91 studies, 87 cross-sectional and 4 cohort, were included. In medical school, mentorship and recruitment of female students into ophthalmology was influenced by sex bias, with fewer females identifying with ophthalmologist mentors and gender stereotypes perpetuated in reference letters written by both male and female referees. In residency, females had unequal learning opportunities, with lower surgical case volumes than male trainees and fewer females pursued fellowships in lucrative subspecialties. In practice, female ophthalmologists had lower incomes, less academic success, and poorer representation in leadership roles. Female ophthalmologists had a greater scholarly impact factor than their male counterparts, but this was only after approximately 30 years of publication experience. Pervasive throughout all stages of training and practice was the experience of greater sexual harassment among females from both patients and colleagues. Despite these disparities, some studies found that females reported equal overall career satisfaction rating with males in ophthalmology, whereas others suggested higher burnout rates.Conclusions and RelevanceOphthalmology is approaching sex parity, however, the increase in the proportion of females in ophthalmology had not translated to an increase in female representation in leadership positions. Sex disparities persisted across many domains including recruitment, training, practice patterns, academic productivity, and income. Interventions may improve sex equity in the field.
A Flexible and Electrically Conductive Liquid Metal Adhesive for Hybrid Electronic Integration
Authors: Pozarycki Tyler A. , Zu Wuzhou , Wilcox Brittan T. , Bartlett Michael D. 
Published: January 2024

AbstractElectrical and mechanical integration approaches are essential for emerging hybrid electronics that must robustly bond rigid electrical components with flexible circuits and substrates. However, flexible polymeric substrates and circuits cannot withstand the high temperatures used in traditional electronic processing. This constraint requires new strategies to create flexible materials that simultaneously achieve high electrical conductivity, strong adhesion, and processibility at low temperature. Here, an electrically conductive adhesive is introduced that is flexible, electrically conductive (up to 3.25×105S m−1) without sintering or high temperature post‐processing, and strongly adhesive to various materials common to flexible and stretchable circuits (fracture energy 350 <Gc< 700 J m−2). This is achieved through a multiphase soft composite consisting of an elastomeric and adhesive epoxy network with dispersed liquid metal droplets that are bridged by silver flakes, which form a flexible and conductive percolated network. These inks can be processed through masked deposition and direct ink writing at room temperature. This enables soft conductive wiring and robust integration of rigid components onto flexible substrates to create hybrid electronics for emerging applications in soft electronics, soft robotics, and multifunctional systems.
Constructing Asymmetrical Coordination Microenvironment with Phosphorus‐Incorporated Nitrogen‐Doped Carbon to Boost Bifunctional Oxygen Electrocatalytic Activity
Authors: Li Zhijun , Ji Siqi , Liu Hongxue , Xu Chang , Guo Chunmin , Lu Xue , Sun Haixin , Dou Shuo , Xin Shixuan , Horton J. Hugh , He Cheng 
Published: January 2024

AbstractCarbon‐based metal‐free electrocatalysts have been recognized as inexpensive alternatives to afford excellent activity in oxygen reduction/evolution reactions (ORR/OER). Nevertheless, precisely identifying the local active sites and tailoring the corresponding electronic properties to enhance the reaction kinetics remain challenging. Herein, a facile strategy to create a metal‐free electrocatalyst comprised of a mesoporous nitrogen‐doped carbon matrix with phosphorus incorporation (NPC) is described. The as‐prepared NPC‐950 electrocatalyst demonstrates superior ORR activity under alkaline and acidic conditions with half‐wave potentials of 0.88 and 0.72 V, respectively, comparable to commercial Pt/C (0.85 and 0.76 V) and overwhelmingly superior to other N‐doped carbon catalyst materials. In addition, a remarkable promotion of OER activity under alkaline conditions is observed. Notably, a zinc–air battery equipped with this NCP‐950 electrocatalyst exhibits exceptional performance in peak power density, specific capacity, and long‐term operation durability. Theoretical calculations uncover that the incorporation of phosphorus in NC material results in effective charge density redistribution, thus modulating the electronic properties of active sites to achieve optimum adsorption and desorption of ORR intermediates. The work provides a deep understanding of active sites in heteroatom‐doped carbon materials and highlights the importance of the electronic properties modulation in oxygen bifunctional electrocatalytic activity.
Interfacial Engineering Using Covalent Organic Frameworks in Polymer Composites for High‐Temperature Electrostatic Energy Storage
Authors: Xie Zongliang , Le Khoi , Li He , Pang Xi , Xu Tianlei , Altoé Virginia , Klivansky Liana M. , Wang Yunfei , Huang Zhiyuan , Shelton Steve W. , Gu Xiaodan , Liu Peng , Peng Zongren , Liu Yi 
Published: January 2024

AbstractThe use of inorganic nanofillers has been an effective method to improve high‐temperature capacitive performance of dielectric polymers, though there are unmet challenges such as undesirable organic–inorganic compatibility, and low efficiencies and energy densities. Herein, a surface functionalization strategy using covalent organic frameworks (COFs) is employed to address such challenges in realizing high‐performing polymer composites. Specifically, core–shell structured nanoparticles, where ZrO2 nanoparticles act as the core and a COF material forms the shell, are constructed and composited with the polyetherimide (PEI) matrix. The design leverages the high electron affinity (EA) of the outer COF shell to create energy traps, thereby capturing free charges and limiting electrical conduction. Concurrently, the low EA and wide bandgap of the ZrO2 core introduce energy barriers to impede charge injection and migration. This orchestrated “energy level cascade” results in a marked reduction of leakage current and energy loss. The resulting polymer composite showcases an impressive discharged energy density of 6.21 J cm−3 at an efficiency above 90%, with a maximum discharged energy density reaching 7.43 J cm−3 at 150 °C. These performance metrics position the PEI/ZrO2@COF polymer composite to surpass or be on par with state‐of‐the‐art high‐temperature PEI composites and other advanced polymer dielectrics.
Boosting Nitrate to Ammonia via the Optimization of Key Intermediate Processes by Low‐Coordinated Cu–Cu Sites
Authors: Huang Kun , Tang Kun , Wang Mohan , Wang Yujiao , Jiang Tongtong , Wu Mingzai 
Published: January 2024

AbstractThe electrochemical reduction of nitrate to ammonia (NO3RR) has emerged as a promising but challenging orientation in sustainable development. Cu is one of the most effective NO3RR catalysts. However, the accumulation of NO2− on their surface has erected bars to the further improvement of NO3RR efficiency. Herein, Cu‐based electrocatalyst with low‐coordinated Cu atoms (Cu‐LC) is synthesized via the instantaneous ablation and rapid cooling of the Cu target by pulse laser and proposed as a new NO3RR electrocatalyst, which exhibits enhanced NO3RR activity with NH3 selectivity of 97.01%, yield rate of 0.624 mmol h−1 cm−2 at −0.8 V versus RHE and long‐term durability, superior to most reported Cu‐based catalysts. The introduction of low‐coordinated Cu sites upshifts the Cu d‐band center to near the Fermi Level, enhancing the adsorption of key intermediates (*NO2, *NO) in NO3RR, and also effectively regulating the generation of *NO2 and hydrogenation process, inhibiting the accumulation of NO2− on the Cu‐LC surface, thus achieving efficient NH3 production. Furthermore, when evaluated as cathode material in Zn–NO3− battery, an open circuit voltage of 1.3 V and a power density of 3.1 mW cm−2 are achieved by the Cu‐LC‐based battery, highlighting a promising multifunctional system for ammonia production and energy supply.
Enhanced Mechanical Properties, Corrosion Resistance, Cytocompatibility, Osteogenesis, and Antibacterial Performance of Biodegradable Mg–2Zn–0.5Ca–0.5Sr/Zr Alloys for Bone‐Implant Application
Authors: Tong Xian , Dong Yilong , Zhou Runqi , Shen Xinkun , Li Yuncang , Jiang Yue , Wang Huiyuan , Wang Jinguo , Lin Jixing , Wen Cuie 
Published: January 2024

AbstractMagnesium (Mg) alloys are widely used in bone fixation and bone repair as biodegradable bone‐implant materials. However, their clinical application is limited due to their fast corrosion rate and poor mechanical stability. Here, the development of Mg–2Zn–0.5Ca–0.5Sr (MZCS) and Mg–2Zn–0.5Ca–0.5Zr (MZCZ) alloys with improved mechanical properties, corrosion resistance, cytocompatibility, osteogenesis performance, and antibacterial capability is reported. The hot‐extruded (HE) MZCZ sample exhibits the highest ultimate tensile strength of 255.8 ± 2.4 MPa and the highest yield strength of 208.4 ± 2.8 MPa and an elongation of 15.7 ± 0.5%. The HE MZCS sample shows the highest corrosion resistance, with the lowest corrosion current density of 0.2 ± 0.1 µA cm−2 and the lowest corrosion rate of 4 ± 2 µm per year obtained from electrochemical testing, and a degradation rate of 368 µm per year and hydrogen evolution rate of 0.83 ± 0.03 mL cm−2 per day obtained from immersion testing. The MZCZ sample shows the highest cell viability in relation to MC3T3‐E1 cells among all alloy extracts, indicating good cytocompatibility except at 25% concentration. Furthermore, the MZCZ alloy shows good antibacterial capability against Staphylococcus aureus.
Spin‐Selective Memtransistors with Magnetized Graphene
Authors: Jeong Juyeong , Kiem Do Hoon , Guo Dan , Duan Ruihuan , Watanabe Kenji , Taniguchi Takashi , Liu Zheng , Han Myung Joon , Zheng Shoujun , Yang Heejun 
Published: January 2024

AbstractSpin‐polarized bands in pristine and proximity‐induced magnetic materials are promising building blocks for future devices. Conceptually new memory, logic, and neuromorphic devices are conceived based on atomically thin magnetic materials and the manipulation of their spin‐polarized bands via electrical and optical methods. A critical remaining issue is the direct probe and the optimized use of the magnetic coupling effect in van der Waals heterostructures, which requires further delicate design of atomically thin magnetic materials and devices. Here, a spin‐selective memtransistor with magnetized single‐layered graphene on a reactive antiferromagnetic material, CrI3, is reported. The spin‐dependent hybridization between graphene and CrI3 atomic layers enables the spin‐selective bandgap opening in the single‐layered graphene and the electric field control of magnetization in a specific CrI3 layer. The microscopic working principle is clarified by the first‐principles calculations and theoretical analysis of the transport data. Reliable memtransistor operations (i.e., memory and logic device‐combined operations), as well as a spin‐selective probe of Landau levels in the magnetized graphene, are achieved by using the subtle manipulation of the magnetic proximity effect via electrical means.
Realization of High Mobility Synaptic Transistor through Control of Cross‐Linking Agent in a Polymer Dielectric Layer for Emerging Electric Double Layer
Authors: Kim Su‐Kyung , Kim Jong‐Ho , Yun Kwang‐Ro , Lee Tae‐Ju , Seong Tae‐Yeon 
Published: January 2024

AbstractThe development of high‐mobility neuromorphic transistors is essential to increase signal transmission speed and solve the von Neumann bottleneck issue. Herein, this work proposes cross‐linked Poly(4‐vinylphenol) (c‐PVP) as a dielectric layer to form an electric double layer (EDL), which plays a key role in synaptic transistors, and measure the ratio‐dependent characteristics of cross‐linking agents in c‐PVP. When the ratio of PVP to poly(melamine‐co‐formaldehyde) methylated (PMF) is 10:1, neuromorphic transistors is found to show the best performance with a memory window of 2.2 V and a mobility of 93.4 cm2 V−1 s−1. Fourier‐transform infrared spectroscopy (FT‐IR) results show that the reduction in the concentration of the cross‐linking agent generates more hydroxyl groups within the c‐PVP film. The 10:1 c‐PVP‐based synaptic device has an ultra‐low energy consumption of 15.8 pJ for a single pulse and a maximum paired pulse facilitation (PPF) index value of 291%. Additionally, synaptic characteristics, such as pulse duration time dependent plasticity, pulse intensity dependent plasticity, pulse rate dependent plasticity (SRDP), high band filtering, and short‐term memory (STM) conversion to long‐term memory (LTM), are also described and discussed. These results suggest that c‐PVP/ZnON‐based neuromorphic devices can be promising artificial synapses for memory and learning capabilities.
Formulating Electron Beam‐Induced Covalent Linkages for Stable and High‐Energy‐Density Silicon Microparticle Anode
Authors: Je Minjun , Son Hye Bin , Han Yu‐Jin , Jang Hangeol , Kim Sungho , kim Dongjoo , Kang Jieun , Jeong Jin‐Hyeok , Hwang Chihyun , Song Gyujin , Song Hyun‐Kon , Ha Tae Sung , Park Soojin 
Published: January 2024

AbstractHigh‐capacity silicon (Si) materials hold a position at the forefront of advanced lithium‐ion batteries. The inherent potential offers considerable advantages for substantially increasing the energy density in batteries, capable of maximizing the benefit by changing the paradigm from nano‐ to micron‐sized Si particles. Nevertheless, intrinsic structural instability remains a significant barrier to its practical application, especially for larger Si particles. Here, a covalently interconnected system is reported employing Si microparticles (5 µm) and a highly elastic gel polymer electrolyte (GPE) through electron beam irradiation. The integrated system mitigates the substantial volumetric expansion of pure Si, enhancing overall stability, while accelerating charge carrier kinetics due to the high ionic conductivity. Through the cost‐effective but practical approach of electron beam technology, the resulting 500 mAh‐pouch cell showed exceptional stability and high gravimetric/volumetric energy densities of 413 Wh kg−1, 1022 Wh L−1, highlighting the feasibility even in current battery production lines.
Butyrate Prevents the Pathogenic Anemia‐Inflammation Circuit by Facilitating Macrophage Iron Export
Authors: Xiao Peng , Cai Xuechun , Zhang Zhou , Guo Ke , Ke Yuehai , Hu Ziwei , Song Zhangfa , Zhao Yuening , Yao Lingya , Shen Manlu , Li Jingyun , Huang Youling , Ye Lingna , Huang Lingjie , Zhang Yu , Liu Rongbei , Xu Mengque , Xu Xutao , Zhao Yuan , Cao Qian 
Published: January 2024

AbstractMost patients with inflammatory bowel disease (IBD) develop anemia, which is attributed to the dysregulation of iron metabolism. Reciprocally, impaired iron homeostasis also aggravates inflammation. How this iron‐mediated, pathogenic anemia‐inflammation crosstalk is regulated in the gut remains elusive. Herein, it is for the first time revealed that anemic IBD patients exhibit impaired production of short‐chain fatty acids (SCFAs), particularly butyrate. Butyrate supplementation restores iron metabolism in multiple anemia models. Mechanistically, butyrate upregulates ferroportin (FPN) expression in macrophages by reducing the enrichment of histone deacetylase (HDAC) at the Slc40a1 promoter, thereby facilitating iron export. By preventing iron sequestration, butyrate not only mitigates colitis‐induced anemia but also reduces TNF‐α production in macrophages. Consistently, macrophage‐conditional FPN knockout mice exhibit more severe anemia and inflammation. Finally, it is revealed that macrophage iron overload impairs the therapeutic effectiveness of anti‐TNF‐α antibodies in colitis, which can be reversed by butyrate supplementation. Hence, this study uncovers the pivotal role of butyrate in preventing the pathogenic circuit between anemia and inflammation.