bluuebunny/crossref_metadata_2025_split huggingface dataset:
Performance of hatchery-produced and feed-weaned fingerlings of striped murrel Channa striata (Bloch, 1793) in biofloc system in the subtropical climate
Authors: Raizada Sudhir , Rawat Anurag , Prakash Prem 
Published: November 2023

The performance of hatchery-produced and pellet-feed-weaned fingerlings of striped murrel, Channa striata (Bloch, 1793) was assessed in the biofloc tanks for growth and survival, in a subtropical climate. The rearing was undertaken in two phases with an increase in fish size. In the first phase, fingerlings (weight 1.94±0.71 g, length 6.29±0.81 cm) were stocked @ 200 m-3 in the biofloc tanks, which were reduced to 15 m-3 in the second phase using the same stock. The fish attained a length of 25.44±1.81 cm and weight of 149.60±28.58 g in 10 months with overall survival of 93% at the end of the second phase. The total fish biomass recorded was 9.7 kg m-3 at the final harvest. The growth parameters were found temperature-dependent, which recorded 15±1.0 to 28±1.5ºC and 'W' values were found to follow Fulton's cube law during the entire culture period. The exponent (b) of 3.278 was recorded as the highest in July 2020 and lowest at 2.210 in December 2020. The lowest R2 was 0.768 and highest 0.943 during December and April respectively whereas, the recorded ‘K’ of 0.611 was the lowest in winter and highest being 0.908 in August. The study demonstrated a higher culture potential of striped murrel with hatchery-produced and feed-weaned seed in the biofloc system with zero-water exchange.
Keywords: Condition factor, Fulton's cube law, Growth, Production, Survival, Zero-water exchange
Effect of water depth on growth and survival of the stinging catfish Heteropneustes fossilis (Bloch, 1794) in pond rearing system of a humid subtropical agroclimatic region
Authors: Debnath Chandan , Sahoo Lopamudra 
Published: November 2023

The growth, survival and proximate composition of Heteropneustes fossilis (Bloch, 1794) were studied under different water depths (30, 60, 90 and 120 cm) for a period of 10 months, with a temperature range of 31.5 to 7.8°C [(May-June; 26.5-31.5°C; Stage 1); (July-September; 28.8-32.6°C; Stage 2); (October-November; 15.5-28.4°C; Stage 3); (December-February; 7.8-15.7°C; Stage 4)] under earthen pond conditions in the humid subtropical climate of Tripura State, India. All the ponds were of equal size (168 m2; 14 m x 12 m) but with different water depths. The fishes were fed with a mixture of rice bran and mustard oil cake (1:1) @ 0.5-3% of their biomass. The growth, survival and proximate composition of fish were recorded in each stage. The average daily weight gain, feed conversion ratio, survival and proximate composition were found to be better in water depths of 60 cm and 90 cm during May to September when water temperature was ≥26.5°C. However, when water temperature was ≤21.4°C (October-February), growth and other attributes significantly reduced. Two-way ANOVA revealed that water depth and temperature, individually and interactively, affected the growth of H. fossilis. From this trial, it can be concluded that H. fossilis performs better when water depth is 60-90 cm and the ideal water temperature for the culture is 28.3-30.4°C. The study confirms the depth preference of H. fossilis under the humid subtropical condition and the information generatedwill help in the sustainable farming of this species.
Keywords:Asian stingingcatfish, Water depth,Temperature, Growth, Survival, Proximate composition
Efficient Thermal-Energy-Storage Chiller Plant Facility Management with Digital Twin-assisted Augmented Reality Application
Authors: Sanzana Mirza Rayana , Abdulrazic Mostafa Osama Mostafa , Wong Jing Ying , Yip Chun-Chieh 
Published: November 2023

Abstract
This study investigates the promising potential of integrating Augmented Reality (AR) and Digital Twin (DT) technologies within the context of Thermal-Energy-Storage (TES) chiller plants' facility management. The objective is to address the challenges posed by noise and discomfort, while also enhancing the efficiency of maintenance tasks. Drawing insights from a survey involving 17 facility management experts, the research unveils that 76.47% of respondents perceived the chiller plant environment as noisy, with 35.29% reporting discomfort. The outcomes reveal a clear inclination towards AR, preferred over Virtual Reality (VR) due to its accessibility and user-friendliness, requiring no additional equipment. Participants laud the remote accessibility and real-time updates facilitated by the AR application enriched with DT assistance. Nevertheless, the study underscores the importance of factoring in hardware limitations and device compatibility during the implementation of AR solutions. Overall, the outcomes affirm the viability and advantages of harnessing AR and DT technologies for enhancing facility management practices in TES chiller plants, all the while acknowledging the avenues for future research and enhancements.
The use of biofluid markers to evaluate the consequences of sport-related subconcussive head impact exposure: a scoping review
Authors: Lember Liivia-Mari , Ntikas Michail , Mondello Stefania , Wilson Lindsay , Virgilio Thomas G Di , Hunter Angus M , Kobeissy Firas , Mchref Yehia , Donaldson David I , Ietswaart Magdalena 
Published: November 2023

Abstract

Background: Amidst growing concern about the safety of sport-related repetitive subconcussive head impacts (RSHI), biofluid markers may provide sensitive, informative, and practical assessment of the effects of RSHI exposure.
Objective: This scoping review aimed to systematically examine the extent, nature, and quality of available evidence from studies investigating the effects of RSHI on biofluid markers, to identify gaps and to formulate guidelines to inform future research.
Methods: PRISMA extension for Scoping Reviews guidelines were adhered to. The protocol was pre-registered through publication. MEDLINE, Scopus, SPORTDiscus, CINAHL, PsycINFO, Cochrane Library, OpenGrey and two clinical trial registries were searched (until 30th March 2022) using descriptors for subconcussive head impacts, biomarkers, and contact sports. Included studies were assessed for risk of bias and quality.
Results: Seventy-nine research publications were included in the review. Forty-nine studies assessed the acute effects, 23 semi-acute and 26 long-term effects of RSHI exposure. The most studied sports were American football, boxing and soccer, and the most investigated markers were (in ascending order): S100 calcium-binding protein beta (S100B), tau, neurofilament light (NfL), glial fibrillary acidic protein (GFAP), neuron-specific enolase (NSE), brain-derived neurotrophic factor (BDNF), phosphorylated tau (p-tau), ubiquitin C-terminal hydrolase L1 (UCH-L1), and hormones. High or moderate bias was found in most studies, and marker-specific conclusions were subject to heterogeneous and limited evidence. Although the evidence is weak, some biofluid markers – such as NfL – appeared to show promise. More markedly, S100B was found to be problematic when evaluating the effects of RSHI in sport.
Conclusion: Considering the limitations of the evidence-base revealed by this first review dedicated to systematically scoping the evidence of biofluid marker levels following RSHI exposure, the field is evidently still in its infancy. As a result, any recommendation and application is premature. Although some markers show promise for the assessment of brain health following RSHI exposure, future large standardized and better-controlled studies are needed to determine biofluid markers’ utility.
Analyzing Variation in State Newspaper Coverage of Climate Change
Authors: Trujillo Rebecca Bromley , Dunk Brandon , Karch Andrew 
Published: November 2023

Abstract
Newspaper coverage of climate change has the potential to shape how the public and elites define this policy problem, the solutions under consideration, and the level of climate change concern. Existing U.S. research focuses exclusively on national coverage, which limits our knowledge of how subnational media outlets report on climate change. In contrast, this study constructs an original dataset of over 12,000 climate-change-related articles that appeared in newspapers in forty-nine U.S. states in 2012 and 2017. We combine manual coding and automated text analysis to assess whether the content of climate change coverage varies systematically across states. Consistent with existing research on journalistic norms, our analysis suggests that coverage reflects geographic differences in the ecological effects of climate change and the specific mix of industries present in a state.
Identification of peptides from honeybee gut symbionts as potential antimicrobial agents against Melissococcus plutonius
Authors: Zheng Hao , Lang Haoyu , Liu Yuwen , Duan Huijuan , Zhang Wenhao , Hu Xiaosong 
Published: November 2023

Abstract
Eusocial pollinators are crucial elements in global agriculture. The honeybees and bumblebees are associated with a simple yet host-restricted gut community, which protect the hosts against pathogen infections. Recent genome mining has led to the discovery of biosynthesis pathways of bioactive natural products mediating microbe-microbe interactions from the gut microbiota. Here, we investigate the diversity and novelty of biosynthetic gene clusters in the bee gut microbiota by analyzing 477 genomes from cultivated bacteria and metagenome-assembled genomes. We identify 744 biosynthetic gene clusters (BGCs) covering multiple chemical classes. While gene clusters for the post-translationally modified peptides are widely distributed in the bee guts, the distribution of the BGC classes varies significantly in different bee species among geographic locations, which is attributed to the strain-level variation of bee gut members in the chemical repertoire. Interestingly, we find that Gilliamella strains possessing a thiopeptide-like BGC show potent activity against the pathogenic Melissococcus plutonius. The spectrometry-guided genome mining reveals a RiPP-encoding BGC from Gilliamella with a 10 amino acid-long core peptide exhibiting antibacterial potentials. This study illustrates the widespread small-molecule-encoding BGCs in the bee gut symbionts and provides new insight into the bacteria-derived natural products as potential antimicrobial agents against pathogenic infections.
Robust contact-constrained topology optimization considering uncertainty at the contact support
Authors: Schmidt Timo , Kriegesmann Benedikt , Seifried Robert 
Published: November 2023

Abstract

In this paper, the general framework for contact-constrained topology optimization of Strömberg and Klarbring [17] is extended to robust topology optimization. In doing so, a linear elastic design domain is considered and the augmented Lagrangian approach is used to model the unilateral contact. For topology optimization, the design space is parametrized with the SIMP-approach and the Sigmund’s filter is applied. Additionally, the robust framework considers uncertainties at the contact support such as deviations of the geometry of the contact surface and the friction coefficient. Both uncertainties are described by the first-order second-moment method which leads to minimal additional costs. In fact, only two addional linear equations must be solved to obtain the robust objective and its gradient with respect to the design variables. Having both the objective and the gradient, the design update is computed with the method of moving asymptodes. The robust framework is applied to 2D and 3D examples to prove its scalabiltiy for real-world applications.
Efficacy and safety of early YAG laser vitreolysis for symptomatic vitreous floaters: the study protocol for a randomized clinical trial
Authors: hangshuai zhou , Yanhua Jin , Yao Zhou , Guangjin Zhao , hongyan Wu , Fanlian Chen 
Published: November 2023

Abstract
Background
Vitreous floaters are a common ocular condition that affects individuals of all ages. Although vitreous floaters are typically benign, they can significantly impair visual acuity and quality of life. Laser vitreolysis, which uses an Nd: YAG laser to vaporize collagenous vitreous opacities, is increasingly being used as a treatment option. However, there is currently a lack of evidence regarding its efficacy and the appropriate timing of its application. The aim of this study is to evaluate the efficacy and safety of early YAG laser vitreolysis in treating symptomatic vitreous floaters.
Methods
The present study is a randomized, controlled, double-blind clinical trial. A total of 70 participants with symptomatic floaters for one month were recruited. These participants will be randomly assigned to two groups, with 35 individuals in each group: the early treatment group and the delayed treatment group. Participants assigned to the early treatment group will undergo YAG laser vitreolysis immediately, followed by a sham laser treatment three months later. On the other hand, participants assigned to the delayed treatment group will receive a sham laser treatment first, and then undergo YAG laser vitreolysis three months later. The follow-up time points will be 1, 3, 6, and 12 months from randomization. Primary outcomes are participants' self-reported improvement in visual disturbance on a scale of 1 to 10 and their scores on the National Eye Institute Visual Functioning Questionnaire 25 (NEI VFQ-25). Secondary outcomes included an objective evaluation of the effectiveness of the treatment in reducing vitreous floaters through OCT and fundus photography and tracking any adverse events related to the eyes or overall health.
Discussion
This clinical trial aims to compare the effectiveness of YAG laser vitreolysis in treating symptomatic vitreous floaters and assess the safety of performing early YAG laser vitreolysis.
Trial registration
clinicaltrials.gov: NCT05800353. Registered March 10, 2023.
https://clinicaltrials.gov/study/NCT05800353
Drivers of unprofessional behaviour between staff in acute care hospitals: A realist review
Authors: Aunger* Justin Avery , Maben* Jill , Abrams Ruth , Wright Judy M. , Mannion Russell , Pearson Mark , Jones Aled , Westbrook Johanna I. 
Published: November 2023

Abstract
Background
Unprofessional behaviours (UB) between healthcare staff are rife in global healthcare systems, negatively impacting staff wellbeing, patient safety and care quality. Drivers of UBs include organisational, situational, team, and leadership issues which interact in complex ways. An improved understanding of these factors and their interactions would enable future interventions to better target these drivers of UB.

Methods
A realist review following RAMESES guidelines was undertaken with stakeholder input. Initial theories were formulated drawing on reports known to the study team and scoping searches. A systematic search of databases including Embase, CINAHL, MEDLINE and HMIC was performed to identify literature for theory refinement. Data were extracted from these reports, synthesised, and initial theories tested, to produce refined programme theories.

Results
We included 81 reports (papers) from 2,977 deduplicated records of grey and academic reports and 28 via Google, stakeholders, and team members, yielding a total of 109 reports. Five categories of contributor were formulated: (1) workplace disempowerment; (2) harmful workplace processes and cultures; (3) inhibited social cohesion; (4) reduced ability to speak up; and (5) lack of manager awareness and urgency. These resulted in direct increases to UB, reduced ability of staff to cope, and reduced ability to report, challenge or address UB. Twenty-three theories were developed to explain how these contributors work and interact, and how their outcomes differ across diverse staff groups. Staff most at risk of UB include women, new staff, staff with disabilities, and staff from minoritised groups. UB negatively impacted patient safety by impairing concentration, communication, ability to learn, confidence, and interpersonal trust.

Conclusion
Existing research has focused primarily on individual characteristics, but these are inconsistent, difficult to address, and can be blamed to deflect organisational responsibility. We present a comprehensive programme theory furthering understanding of contributors to UB, how they work and why, how they interact, whom they affect, and how patient safety is impacted. More research is needed to understand how and why minoritised staff are disproportionately affected by UB.

Study registration
This study was registered on the international database of prospectively registered systematic reviews in health and social care (PROSPERO): https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42021255490

*Justin Avery Aunger and Jill Maben should be considered joint first author.
MicroRNAs in epilepsy: a bibliometric study from 2007 to 2023
Authors: Ling Yuanyuan , Tong Xiaoqiong , Tang Ming , Li Zhengling , Zeng YuMei , Liu Zhifan , Jiang Guohui 
Published: November 2023

Abstract
Background and objective:
MicroRNAs are a class of endogenous small non-coding single-stranded RNA molecules. It regulates gene expression at the post-transcriptional level by binding to one or more mRNA molecules that are partially complementary. microRNA has also been extensively studied in epilepsy. This study aimed to evaluate the current status of microRNA research in epilepsy and to identify research hotspots and trends using bibliometric and visual analysis methods.
Methods
We used Scopus, the largest literature abstract and citation database, to search for literature that met the inclusion criteria. Citespace6.2. R 3, VOSviewer 1.6.17, Excel, and Scimago Graphica visualization and analysis tools were used to analyze countries, institutions, authors, journals, references, and keywords in the field.
Results
A total of 929 publications were included. There was a large number of publications and citations related to epilepsy and microRNAs. The International Journal of Molecular Sciences was the journal with the largest number of papers published on epilepsy and microRNAs, and the Royal College of Surgeons of Ireland was the issuing organization with the largest volume of papers. Through a comprehensive analysis of keywords and references, we identified the priorities and future research trends in epilepsy and microRNA.
Conclusions
We used bibliometric methods to describe the current research status of microRNA and epilepsy, and the main content and future research trends of epilepsy and microRNA, including the top three microRNAs, inflammation, oxidative stress, drug resistance-related proteins, blood-brain barrier function, neuroplasticity, exosome, lncRNA, other diseases, and biomarkers.
Quantifying Tidal versus Non-tidal stresses in Driving Time-Varying Fluxes of Enceladus’ Plume Eruptions
Authors: Schoenfeld Ashley Marie , Yin An 
Published: November 2023

Abstract

One of the most important questions in planetary-tectonics research is whether endogenic stresses, such as mantle convection on Earth, play a significant role in governing global tectonic evolution of a solar-system body. In this study, we investigate the relative importance of endogenic vs. exogenic stresses in controlling the spatial location and temporal variation of active ice-shell deformation on Enceladus, which is expressed by cyclic plume eruptions along active fault zones (i.e., the tiger stripes). Although the variation of the eruption flux on Enceladus follows the periodicity of the diurnal tide, it remains unclear why there is a consistent phase delay of the observed peak eruption when compared to the predicted peak tidal stress. Here, we explore whether endogenic stresses in the ice shell are capable of explaining this observed phase delay. To achieve this goal, we performed geologic mapping along the tiger-stripe faults that host the erupting plumes. Using the fault kinematics established from our mapping, we determine the general stress state (i.e., the principal-stress directions) along the tiger-stripe faults. This knowledge in turn forms the basis for inferring the most likely plume-eruption mechanism. Our mapping shows that the tiger-stripe fractures are not tensile cracks but are instead left-slip fault zones locally displaying extensional fissures. This insight leads to a hypothesis that strike-slip faults and their local tensile cracks experience simultaneous shear and tensile failure, and that the tensional opening reaches maximum at the time of the peak plume flux. We quantified this hypothesis using a stress decomposition model that assesses (1) the relative importance in magnitude between the tectonic stress and tidal stress exerted on the tiger-stripe faults and (2) the role of ice-shell properties such the shear and tensile strengths and ice-shell thickness in controlling the eruption phase delay. Using laboratory-determined ice strengths and the best estimate of the ice-shell thickness at the South Polar Terrain of Enceladus, which hosts the tiger-stripe faults, our model results indicate that the endogenic tectonic stress is comparable in magnitude to the tidal stress. Although we cannot rule out warm-ice convection, true polar wander, and non-synchronous rotation as causes of endogenic stresses, the large variation in ice-shell thickness makes the lateral gravitational-potential gradient the most plausible source of the endogenic stress required by our model results.
Electro-driven direct lithium extraction from geothermal brines to generate battery-grade lithium hydroxide
Authors: Liu Xitong , Kong Lingchen , Yan Gangbin , Hu Kejia , Yu Yongchang , Conte Nicole , McKenzie Kevin , Wagner Michael , Boyes Stephen , Chen Hanning , Liu Chong 
Published: November 2023

Abstract
As Li-ion batteries are increasingly being deployed in electric vehicles and grid-level energy storage, the demand for Li is growing rapidly. Extracting lithium from unconventional aqueous sources such as geothermal brines plays an important role in meeting this demand. Electrochemical intercalation offers high Li selectivity and avoids the use of harsh chemical regenerants, thus holding great promise in directly extracting lithium from unconventional sources. In this work, we design an integrated electrochemical process that achieves selective lithium extraction from geothermal brine, purification of lithium chloride, and conversion to lithium hydroxide. The lithium extraction process utilizes a lithium-intercalation electrode, LiFePO4 (LFP), as the working electrode coupled with an activated carbon electrode as the counter electrode. A 91% purity LiCl is extracted from simulated Salton Sea geothermal brine containing 42 mM Li+, 3.1 M Na+ (Li/Na molar ratio 1:74), 1070 mM Ca2+, and 540 mM K+, and a further purification step achieves a pure LiCl solution with no Na detected. Subsequently, lithium hydroxide is further produced through a bipolar membrane electrodialysis system and finally crystallized to obtain battery grade (> 99.5% purity) LiOH•H2O solid. We investigated the selectivity of lithium separation in solutions with different cation concentration ratios as well as in synthetic geothermal brines. We further conducted density-functional theory (DFT) calculations to elucidate the mechanisms underlying the high Li selectivity of olivine FePO4 in aqueous solution. Finally, we conducted techno-economic assessments using a parametric model and estimated the levelized cost of produced LiOH•H2O (LCOL) as 4.1 $/kg LiOH•H2O, which is 6 times lower than the current market price. The results demonstrate the great potential of our technology for electro-driven, chemical-free lithium extraction from unconventional sources.