bluuebunny/crossref_metadata_2025_split huggingface dataset:
Structural Validation of the Manchester-Oxford Foot Questionnaire (MOxFQ) for use in Foot and Ankle Surgery
Authors: Borsky Kim , Goodall Richard , Harrison Conrad , Welck Matthew J. , Malhotra Karan , Rodrigues Jeremy 
Published: December 2023

Category: Other Introduction/Purpose: The Manchester-Oxford Foot Questionnaire (MOxFQ) is a condition specific patient reported outcome measure (PROM) for foot and ankle surgery. It consists of 16 items across three subscales measuring distinct, but related traits: walking/standing ability, pain, and social interaction. Although it is the most used foot and ankle PROM in the UK, initial MOxFQ validation involved analysis of only 100 individuals undergoing hallux valgus surgery. This project aimed to establish whether an individual’s response to the MOxFQ varies with anatomical region of disease (measurement invariance), and to explore structural validity of the factor structure (subscale items) of the MOxFQ. Methods: This was a single-centre, prospective cohort study involving 6640 patients (mean age 52, range 10-90 years) presenting with a wide range of foot and ankle pathologies between 2013 and 2021. Firstly, to assess whether the MOxFQ responses vary by anatomical region of foot and ankle disease, we performed multi-group confirmatory factor analysis. Secondly, to assess the structural validity of the subscale items, exploratory and confirmatory factor analyses were performed. Results: Measurement invariance by pathology was confirmed suggesting the same model can be used across all foot and ankle anatomical regions. Exploratory factor analysis demonstrated a 2-3 factor model, and suggested that item 13 (inability to carry out my work/everyday activities) and item 14 (inability to undertake social/recreational activities) loaded more positively onto the walking/standing subscale than their original social interaction subscale. Conclusion: This large-cohort study supports the current widespread use of the MOxFQ across a broad range of foot and ankle pathologies. Items 13 and 14 might be better moved from the “social interaction” to the “walking/standing” subscale and this may have future implications for deriving/analysing subscale scores.
Subtalar Joint Fusion For STJ OA before vs after Total Ankle Replacement: Does it affect patient outcomes? – A 10 year follow up clinical study
Authors: Hakeem Samir , Nicolas Andrea Pujol , Porter Anna , Ramaskandhan Jayasree R. , Siddique Malik 
Published: December 2023

Category: Ankle; Hindfoot Introduction/Purpose: There is paucity of literature reporting outcomes in patients who undergo subtalar joint fusion surgery before vs. after having a Total Ankle Replacement (TAR). We aimed to study the PROMs in patients who underwent a staged approach of Subtalar arthrodesis (STJA) followed by TAR vs patients who underwent TAR followed by further STJA surgery. Methods: All patients who underwent a STJA surgery and TAR surgery (in either order) between 2006 and 2010 included in this study. patient reported outcomes including WOMAC (Western Ontario McMasters Osteoarthritis score), SF-36 general health score and patient satisfaction scores were compared between groups. They analysed pre-operatively and at 1, 2, 5 and 10 years post-operatively. Out of 210 TARs performed, 14 patients underwent a two staged procedure between 2006 and 2010 by a single surgeon. 5 patients had STJ fusion after TAR (Group A) and 9 patients had STJ fusion before TAR (Group B). Results: Mean age of Group A and B was 52.5 years and 62.1 years respectively. 1 patient in Group A and 3 patients in Group B were deceased. Both groups reported improvement in scores for WOMAC, SF -36 from pre-op to 1 year post operatively (p < 0.05) and the results plateaued to 5 years with slight decline in scores from 5 to 10 years. At 2 years, Group B reported lower scores for stiffness (9.6±11.7 vs. 64.3 ±27.4) p=0.002, At 5 years, Group A reported lower scores than group B for General health and mental health components of SF-36 scores (p=0.044); however, there was no differences between groups for WOMAC, SF-36 and patient satisfaction outcomes at 10 years post-operatively. Conclusion: There were similar outcomes reported by patients who underwent STJA either before or after TAR at average of 10 year follow up in this series
Suture Button Fixation for Lisfranc Injuries: A Systematic Review
Authors: Lachance Andrew , Jonas Margaret , Edelstein Alexander , Lee Wonyong 
Published: December 2023

Category: Midfoot/Forefoot; Trauma Introduction/Purpose: Lisfranc injuries remain a significant but often misdiagnosed orthopaedic injury. Alongside traditional methods of surgical fixation, including arthrodesis and ORIF with screws, suture button fixation is an emerging technique. While several studies have reviewed the outcomes of Lisfranc injuries utilizing plate, screw, and k-wire constructs for arthrodesis or ORIF, there has yet to be a review of the literature focusing on suture button fixation outcomes of Lisfranc injuries. The purpose of this systematic review is to consolidate studies utilizing suture button fixation for the treatment of Lisfranc injuries. Methods: A comprehensive literature review was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) using PubMed, Embase, Web of Science, and Cochrane databases for original, English-language studies observing outcomes of Lisfranc injury until August 19, 2022. This combination search strategy employed the following keywords: ((Lisfranc OR Midfoot OR Tarsometatarsal) AND (Injury OR Instability OR Fracture OR Dislocation)) AND (ORIF OR Fixation OR Reconstruction OR suture* OR button* OR Fiber*). The quality of all included studies in this review was evaluated by a modified Coleman score. Clinical outcomes including pre and postoperative American Orthopaedic Foot and Ankle Society (AOFAS) score, pre and postoperative Visual Analogue Scale (VAS) for pain, and radiographic outcomes such as diastasis were extracted from the text and figures of each study. Return to sports/duty and time to return as well as postoperative complication diagnoses and complications were also extracted from each article. Results: Of the 10 studies included, there were 186 total patients with an age range of 13-72. In every study, all patients were able to return to sport or activity with a return time averaging from 10.8-55.1 weeks. Postoperative AOFAS scores ranged from 83.5- 97 while VAS ranged from 0.6-2.5. Complications were reported in six studies at a rate of 6.7 % including two cases of diastasis, two cases of paresthesia, one case of button irritation, and one of postoperative degenerative joint disease, with no reported revisions. Conclusion: This study summarizes the current evidence regarding suture button fixation of Lisfranc injuries including return to sport, postoperative diastasis, and patient-reported outcomes. In sum, these studies found that suture button fixation shows high levels of patient-reported outcomes, return to sport, and stable fixation in isolated Lisfranc injuries. This surgical technique is advantageous as it provides a more physiologic reduction across the Lisfranc joint and reduces the need for reoperation including the removal of hardware. Further evidence such as large sample size and high-quality RCT studies is needed to draw a definitive conclusion regarding the best treatment for Lisfranc injuries.
Talar Neck Rotation Angle in Adults with Clubfoot Deformity: Observed Values and Intra- and Inter- Observer Reliability using Weightbearing CT
Authors: Malhotra Karan , Colta Raul , Haldar Anil , Patel Shelain , Welck Matthew J. , Cullen Nicholas 
Published: December 2023

Category: Ankle; Basic Sciences/Biologics Introduction/Purpose: Adults presenting with symptomatic clubfoot represent a challenging cohort of patients. An appreciation of the location and degree of deformities is essential for management. Talar anatomy is often abnormal with varus within the talar neck, however, there are few reproducible methods which quantify talar neck deformity in adults. We describe a technique of assessing talar neck deformity, and report on observed values and intra- / inter-observer reliability. Methods: This was a single-centre, retrospective study including 96 feet from 56 adult patients with clubfeet (82 feet had clubfoot deformity, 14 were normal). Mean age was 34.3±16.9 years and 31 (55.3%) were male. Weight-bearing CT scans captured as part of routine clinical care were analysed. Image reformats were oriented parallel to the long axis of the talus in the sagittal plane. In the corresponding axial plane two lines were drawn (on separate slices): 1) a line perpendicular to the intermalleolar axis, 2) a line connecting the midpoints of the talar head and narrowest part of the talar neck. The talar neck rotation angle (TNR angle) was the angle formed between these lines. Intraclass correlation coefficients (ICC) were performed for intra- and inter-observer reliability. Results: Mean TNR angle in clubfeet was 27.6±12.2 degrees (95%CI = 25.0 to 30.2 degrees). Mean TNR angle in normal feet was 18.7±5.1 degrees (95%CI = 16.0 to 21.4 degrees) (p < 0.001). The ICC for clubfeet was 0.944 (95%CI = 0.913 to 0.964) for intra- observer agreement, and 0.896 (95%CI = 0.837 to 0.932) for inter-observer agreement. Conclusion: This measurement technique demonstrated excellent intra- and inter-observer agreement. It also demonstrated that compared to normal feet, clubfeet had about 9 degrees of increased varus angulation of the talar neck. This technique and data may be used for future research into clubfoot deformity and in planning treatment.
Talonavicular Dislocations: A Bad Actor Made Worse Without Sufficient Fixation
Authors: Campbell Megan L. , Siebert Matt , Sroka Oliver , Haller Justin , Marchand Lucas 
Published: December 2023

Category: Trauma; Midfoot/Forefoot Introduction/Purpose: The talonavicular joint (TNJ) is critical to midfoot architecture, and traumatic disruptions of this joint threaten the midfoot arch. We sought to better elucidate injuries to the TNJ and understand if transient methods of stabilization after TN dislocations (TNDs), such as closed/open reduction with or without percutaneous pinning resulted in different radiographic and clinical outcomes when compared to more permanent methods such as bridge plating or primary arthrodesis of the TNJ. Methods: We retrospectively identified skeletally mature patients from one tertiary level 1 trauma center treated for midfoot injuries between 2002-2022. Patients with isolated or concomitant TNDs were included. Demographics, treatment, radiographic outcomes, and patient reported outcomes (PROs) were recorded. Patients who underwent temporary fixation methods (closed/open reduction and trans-articular pinning with k-wire removal at 6-8 weeks) were compared to those with permanent fixation (bridge plating or primary arthrodesis). Primary outcome was reoperation, including fusions and amputations. Secondary outcomes were radiographic arch measurements (Meary’s angle [MA], calcaneal inclination angle [CIA]) and PROMIS measures of physical function, pain interference, and anxiety. Sixty-two patients and 66 feet were included (Table 1). Average follow up was 2 years. Results: TNDs manifested as both pure dislocations (18) and in conjunction with associated injuries: chopart dislocations (5), talar head/body fractures (23), navicular fractures (35), and subtalar dislocations (25). Twelve were a part of Hawkins IV talar neck fracture dislocations (18%). Forty-two patients were treated with temporary fixation (64%). Injuries treated with transient fixation had higher mean change in MA from immediately postop to final follow-up (-7.9° v -1.1°, p=0.006). They also exhibited significantly different MA and CIA values at final follow-up (7.8° v -1.4°; 17.3° v 21.3°, p< 0.03). Nearly two thirds required reoperation; 32% underwent fusion and 7% required amputation. Fixation method had no significant association with PROMIS scores, but those with temporary fixation methods trended toward lower final PF scores (34.9 v 41.1, p=0.11). Conclusion: TNDs are generally the result of high energy mechanisms, often occurring in combination with other significant mid/hindfoot injuries. Reduction and fixation method of these injuries should be carefully considered to avoid potential ramifications of loss of normal arch and midfoot sag.
The Effect of Focused Vibration on Tibialis Anterior Function in Normal Subjects
Authors: Lui Chun Wai , Loureiro Rui CV , Malhotra Karan 
Published: December 2023

Category: Basic Sciences/Biologics; Other Introduction/Purpose: Foot drop is a debilitating condition which may be caused by peripheral nerve pathology. Focused vibration therapy (FVT) is a novel treatment in this setting which aims to improve the response of muscle motor units to nervous stimuli, improving muscle function and rehabilitation potential. This study investigates the effect of FVT on tibialis anterior (TA) function in normal subjects to determine the optimal timing of application. Methods: Fifteen normal subjects with mean age 25.47±3.27 years and BMI of 21.93±1.54kg/m2 were recruited. Using surface electromyography (EMG), a rotary potentiometer, video analysis (KINOVEA software), and force gauges, the activity of TA, ankle range of movement (ROM), and force at maximal isometric voluntary contraction (MVC) in dorsiflexion were measured. Baseline TA strength was recorded, and participants then performed a series of dorsiflexion exercises to induce fatigue. Strength measurements were repeated after a 5-minute rest period (control). This process was repeated with FVT applied before exercise (FVBE) and after exercise (during the rest period, FVAE). FVT was delivered over the TA muscle belly at 75Hz / 0.4mm amplitude. Data was analysed using ANOVA. Results: There was no significant change in EMG readings or dorsiflexion ROM between baseline, control and FVBE/FVAE measurements. Compared to baseline, MVC increased by 10.87N (6.6%) after FVBE (p=0.034) and 13.87N (8.4%) after FVAE (p=0.034). Compared to control, MVC did not increase significantly with FVBE, but did increase by 7.70N (4.3%) following FVAE (p=0.049). Conclusion: FVT improved the MVC of TA - this was most pronounced when FVT was applied during the recovery phase, after exercise. The lack of EMG / ROM improvement is expected in normal subjects. Our results suggest that FVT is more effective than passive rest and may enhance muscle strength recovery. Further work will investigate the optimal dose of FVT and response in patients with pathology.
The Keystone of Muller Weiss Disease: How Does the Compressed Navicular Cause the Cascade of Deformities in the Mid and Hind Foot?
Authors: Hu Haonan , Gu Wanjun , Zhu Mingjie , Sun Chengyi , Zhang Mingzhu , Myerson Mark , Li Shuyuan 
Published: December 2023

Category: Hindfoot; Midfoot/Forefoot Introduction/Purpose: It is believed that Müller Weiss Disease (MWD) starts with narrowing of the lateral and dorsal side of the navicular, followed by lateral rotation and slight dorsal lifting of the talar head and medial rotation of the navicular, a varus heel, and ultimately additional changes in the hindfoot and midfoot. This study used the technique of distance mapping to measure the space of the “peri-navicular” joints on an averaged 3D foot model for both normal controls and a group of MWD feet, to prove the key pathologic changes of MWD. Methods: Weight bearing Scans of 55 health feet without deformities, trauma and surgical history, and 69 feet with MWD were included in this study. The Bonelogic program (Disior, Paragon28) was used to automatically segment the bones and 3D information of each foot in the same group was pooled to create an average foot model for both the controls and the MWD feet. On the two foot models, distance mapping was applied and compared to compare the space of the perinavicular joints (the talonavicular joint, the three navicular cuneiform joints, and the calcaneocuboid joint). The morphology of the navicular bone and the talonavicular articulation in the two groups were also studied. Results: In the MWD foot model, there was significant narrowing of the lateral pole and the dorsal side of the navicular compared with the average normal foot model. The bone articular surfaces of the two foot models matched well, meaning that the deformity changes occurred predominantly to the shape of the navicular but not the contour of the joint surface. The joint space measured using distance mapping was significantly greater in the talonavicular joint, middle and lateral naviculocuneiform joints, and the calcaneocuboid joint in the MWD feet than in normal controls. There was no difference in the joint space of the medial naviculocuneiform joint between the two foot models. Conclusion: It is the change in the shape of navicular bone but not articular surface contour which causes the development of the cascade of deformities in MWD. The sequalae includes increased joint space on both sides of navicular tail, and in the calcaneocuboid joint, lateral subluxation of the talus head, relative medial subluxation of the navicular, a varus heel with more opening in the sinus tarsi, proximal shift of the calcaneal tuberosity, a flat medial arch with subsidence at the talonavicular joint, decreased adduction of the forefoot, medial translation of the cuboid at the calcaneocuboid articulation, and a shortened 1st metatarsal.
The Proximal 5th Metatarsal Fracture: A Spectrum of Misunderstood Fractures
Authors: Kingery Matthew T. , Kadiyala Manasa , Walls Raymond J. , Leucht Philipp , Rivero Steven , Ganta Abhishek , Konda Sanjit , Egol Kenneth A. 
Published: December 2023

Category: Midfoot/Forefoot; Trauma Introduction/Purpose: Several different types of 5th metatarsal fractures exist and are treated with various methods of immobilization, weight bearing restrictions, and occasionally operative procedures. The purpose of this study was to evaluate the differences in clinical and radiographic outcomes between pseudo-Jones fractures (Zones 1 and 2 of the 5th MT base), True Jones fractures (Zone 3), and 5th MT shaft fractures. Methods: This was a retrospective cohort study of patients presenting to a single large, urban, academic medical center with any 5th MT fracture between 2012 and 2022. Inclusion criteria for this analysis included patient follow up until there was evidence of radiographic healing, clinical healing, or duration greater than one year following injury. Radiographs obtained at the initial presentation were reviewed and fracture patterns were categorized as either Zone 1, Zone 2, Zone 3, or Shaft. Linear regression models were used to evaluate the effect of fracture type on the duration of healing when controlling for age, sex, BMI, smoking status, and history of diabetes. 1,279 patients with 5th metatarsal fracture met the inclusion criteria and were included in the analysis (mean age 49.2 +/- 17.9 years). Overall, 5.2% were treated in a splint or cast, 67.5% in a CAM boot, 20.3% in a hard sole shoe, and 7.0% without immobilization. Results: 31.2% of patients were non-weight bearing, 8.1% partial weight bearing, and 60.7% weight bearing as tolerated. There was no difference in time to radiographic union (p=0.946) or time to clinical healing (p=0.520) between any of the fracture types. Similarly, there was no difference in the proportion of patients with incomplete radiographic healing at 6 months (p=0.310) and at 1 year after injury (p=0.552) based on the fracture type. Likewise, there was no difference in any clinical or radiographic healing parameter based on fracture type for patients treated operatively. Based on linear regression model, there was no difference in the time to clinical or radiographic healing when controlling for confounding factors. Conclusion: All commonly occurring 5th metatarsal fractures, including those of both the metatarsal base and the shaft, demonstrate similar times to clinical and radiographic healing.
The Use of the Lateral Tibial Line to Assess Ankle Alignment: A Preliminary Investigation
Authors: Striano Brendan M. , Patel Shalin S. , Parker Emily Belle , Smith Jeremy , Vaughn Joshua , Harris Mitchel , Chiodo Christopher P. 
Published: December 2023

Category: Ankle; Trauma Introduction/Purpose: Although the medial clear space (MCS) is commonly used to assess talar alignment and ankle stability, its measurement is variable with multiple reported “normal” values. We have observed that the lateral tibial shaft is a reliable landmark to assess talar alignment. The objective of the current investigation was to determine the normal relationship of the lateral tibia to the superolateral talus using a tangent drawn inferiorly from the lateral tibial shaft, which we refer to as the “lateral tibial line” (LTL). Methods: The relationship of the LTL to the superolateral talus was assessed and characterized on ninety-nine standing ankle mortise radiographs in uninjured patients. This relationship was quantified by measuring the distance (in millimeters) between the LTL and the superolateral talus. Additionally, the inter-observer reliability of the LTL measurement, determined by three reviewers, was recorded and compared to medial clear space measurements. Results: The median value for the lateral tibial line was -0.50 mm with an interquartile range of -1.4mm - 0.0mm. The LTL was within 1mm of the lateral talus in 176 of 297 reviewer measurements (59.3%). Moreover, it was either lateral to or was at most 1mm medial to the lateral talus in 90.9% of cases. The LTL measurement also demonstrated good inter-observer reliability (0.764, 95% CI: 0.670-0.834), similar to the measurement of MCS (0.742, 95% CI: 0.539-0.846). Conclusion: The LTL is easily measured with good reliability for assessing the anatomic relationship of the tibia and talus. It uncommonly fell more than 1 mm medial to the superolateral talus. In other words, it was uncommon for the talus to shift lateral to this line, as might be seen with displaced ankle fractures. These findings will hopefully serve as a standard for future studies evaluating the role of the LTL in assessing lateral displacement and stability of isolated fibula fractures.