bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluating machine learning-enabled and multimodal data-driven exercise prescriptions for mental health: a randomized controlled trial protocol
Authors: Tan Miaoqing , Xiao Yanning , Jing Fengshi , Xie Yewei , Lu Sanmei , Xiang Mingqiang , Ren Hao 
Published: January 2024

BackgroundMental illnesses represent a significant global health challenge, affecting millions with far-reaching social and economic impacts. Traditional exercise prescriptions for mental health often adopt a one-size-fits-all approach, which overlooks individual variations in mental and physical health. Recent advancements in artificial intelligence (AI) offer an opportunity to tailor these interventions more effectively.ObjectiveThis study aims to develop and evaluate a multimodal data-driven AI system for personalized exercise prescriptions, targeting individuals with mental illnesses. By leveraging AI, the study seeks to overcome the limitations of conventional exercise regimens and improve adherence and mental health outcomes.MethodsThe study is conducted in two phases. Initially, 1,000 participants will be recruited for AI model training and testing, with 800 forming the training set, augmented by 9,200 simulated samples generated by ChatGPT, and 200 as the testing set. Data annotation will be performed by experienced physicians from the Department of Mental Health at Guangdong Second Provincial General Hospital. Subsequently, a randomized controlled trial (RCT) with 40 participants will be conducted to compare the AI-driven exercise prescriptions against standard care. Assessments will be scheduled at 6, 12, and 18 months to evaluate cognitive, physical, and psychological outcomes.Expected outcomesThe AI-driven system is expected to demonstrate greater effectiveness in improving mental health outcomes compared to standard exercise prescriptions. Personalized exercise regimens, informed by comprehensive data analysis, are anticipated to enhance participant adherence and overall mental well-being. These outcomes could signify a paradigm shift in exercise prescription for mental health, paving the way for more personalized and effective treatment modalities.Registration and ethical approvalThis is approved by Human Experimental Ethics Inspection of Guangzhou Sport University, and the registration is under review by ChiCTR.
Research on the healthy life expectancy of older adult individuals in China based on intrinsic capacity health standards and social stratification analysis
Authors: Liu Mengya , Zhang Meng , Zhou Jinglei , Song Nannan , Zhang Li 
Published: January 2024

BackgroundBased on the health standard of intrinsic capacity, this paper conducts an empirical study on the healthy life expectancy of older adult individuals aged 60 and older in China and analyzes the health inequities associated with different social characteristics to provide a reference for improving care for the older adult in China.MethodsData from the China Health and Retirement Longitudinal Study from 2011 to 2015 were used to evaluate the intrinsic capacity level of older adult individuals, and the multistate life table method was used to measure the healthy life expectancy of older adult individuals in China with the help of IMaCH software. Based on the theory of social stratification, the health inequality between older adult individuals in different social classes was analyzed in three dimensions: residence, income and education level.ResultsThe calculation results show that the average life expectancy of the older adult in China at age 60 is 21.07 years, the healthy life expectancy is 16.89 years, and the healthy life expectancy accounts for 80.2% of the average life expectancy. The healthy life expectancy of older adult individuals with different social characteristics in China shows significant differences, and the healthy life expectancy of older adult individuals who are male, live in urban environments, have high levels of education and have middle- to high-income levels is significantly better than that of older adult individuals who are female, live in rural areas, have low levels of education and income.ConclusionHealthy life expectancy measured by intrinsic capacity as the health standard has a certain reference value, which reflects the overall health level of older adult individuals in China and expands the transformation and multidimensional understanding of the healthy thinking of older adult individuals in China. The analysis by social stratification reflects the large health inequities that exist in the older adult population in China.
Trend and factors associated with non-suppression of viral load among adolescents on ART in Tanzania: 2018–2021
Authors: Quaker Andrewleon S. , Shirima Laura J. , Msuya Sia E. 
Published: January 2024

BackgroundTanzania is one of the countries with a high burden of HIV. It has an estimated 1.4 million people living with HIV in 2021. Adolescents living with HIV on antiretroviral therapy (ART) have worse treatment adherence, viral suppression, and mortality rates compared to adults. This study aim was to determine the trend of non-suppression among adolescents on ART in Tanzania from 2018 to 2021 and latest associated predictors.MethodologyThe study utilized data of adolescents (10–19 years) receiving ART in Tanzania mainland for the period of 2018–2021 from the National Care and Treatment Centers database. The primary outcome of interest was non-suppression of viral load, defined as a VL above 1,000 copies/ml. The study employed multivariable logistic regression models to identify factors associated with non-suppression of VL. STATA 15 statistical software was used to analyze the data.ResultsRecords of 65,942 adolescents present in the CTC database Tanzania were analyzed. Approximately more than half were female 38,544 (58.5%). The proportion of non-suppression was 34.5%, 23.3%, 12.1%, and 9.7% for the years 2018–2021, respectively. After adjusting for other factors, adolescents with a history of poor adherence to ART in the last six months had higher odds of non-suppression (OR = 1.95, 95% CI = 1.64, 2.31). Adolescents on second or third line ART regimens were almost two times more likely to be non-suppressed compared to those on first-line regimens (OR = 2.85, 95% CI = 2.52, 3.23). Girls had lower odds of non-suppression compared to boys (OR = 0.91, 95% CI = 0.84, 0.98), and similarly, patients attending hospitals had lower odds compared to those attending dispensaries (OR = 0.79, 95% CI = 0.72, 0.87).ConclusionBeing female, having good history of adherence over the last six months, and attending hospital level was significantly associated with lower levels of non-suppression, while being on second line ART or attending lower health facilities increased the odds of non-suppression. Efforts to enhance the quality and capacity of health services at lower-level facilities (dispensaries and health centers) should be prioritized, as well as promoting gender-sensitive approaches that take into account the unique needs and experiences of adolescent girls and boys are needed to improve VL suppression among this population.
An effect of a snow cover on solar heating and melting of lake or sea ice
Authors: Dombrovsky Leonid A. 
Published: January 2024

Solar radiative heating and melting of lake and sea ice is a geophysical problem that has attracted the attention of researchers for many years. This problem is important in connection with the current global change of the climate. Physical and computational models of the process are suggested in the paper. Analytical solutions for the transfer of solar radiation in light-scattering snow cover and ice are combined with numerical calculations of heat transfer in a multilayer system. The thermal boundary conditions take into account convective heat losses to the ambient air and radiative cooling in the mid-infrared window of transparency of the cloudless atmosphere. The study begins with an anomalous spring melting of ice on the large high-mountain lakes of Tibet. It was found that a thick ice layer not covered with snow starts to melt at the ice-water interface due to volumetric solar heating of ice. The results of the calculations are in good agreement with the field observations. The computational analysis showed a dramatic change in the process when the ice is covered with snow. A qualitative change in the physical picture of the process occurs when the snow cover thickness increases to 20–30 cm. In this case, the snow melting precedes ice melting and water ponds are formed on the ice surface. This is typical for the Arctic Sea in polar summer. Known experimental data are used to estimate the melting of sea ice under the melt pond. Positive or negative feedback related to the specific optical and thermal properties of snow, ice, and water are discussed.
First detection and molecular characterization of porcine reproductive and respiratory syndrome virus in Namibia, Africa
Authors: Molini Umberto , Coetzee Lauren M. , Hemberger Maria Y. , Chiwome Bernard , Khaiseb Siegfried , Dundon William G. , Franzo Giovanni 
Published: January 2024

IntroductionThe swine sector in Africa plays an important role in local economies, contributing to poverty alleviation and community subsistence. In addition, intensive farming is progressively becoming more important in the region. Therefore, any disease affecting swine populations can have detrimental effects on local communities. Porcine Reproductive and Respiratory Syndrome (PRRS) is among the most important infectious diseases affecting swine worldwide, but information on its epidemiology in Africa is extremely limited.Material and methodsIn the present study, 147 healthy butchered pigs, originating from 15 Namibian intensive and rural farms were tested by RT-PCR and the ORF7 genes of positive samples were sequenced for further genetic characterization and phylogenetic analysis. Additionally, 55 warthogs were also evaluated using the same approach.ResultsOverall, 7 out of 147 pigs (4.76%) tested positive, all originating from 3 rural farms (with a within-herd detection frequency higher than 14%) characterized by strong epidemiological links. All industrial pig and warthog samples were negative. Sequence analysis revealed that all strains belonged to the Betaarterivirus suid1 species, previously known as PRRSV type I, and were likely imported from Europe at least 6 years ago, evolving independently thereafter. When and how the first introduction occurred could not be determined due to the absence of other African sequences for comparison.DiscussionThe present work provides the first detection and characterization of PRRSV molecular epidemiology in Namibia. Based on the present findings, the presence of the PPRSV appears marginal and limited to backyard farms. While biosecurity measures applied in industrial farms appear to be effective in preventing viral introduction, PRRSV circulation in rural settings still represents a potential threat, and considering the socio-economical implication of livestock diseases decreasing animal performances in rural areas, active monitoring should be encouraged to promptly act against emerging menaces and guarantee the welfare of local pig populations.
China-origin G1 group isolate FPV072 exhibits higher infectivity and pathogenicity than G2 group isolate FPV027
Authors: Xie Qiaoqiao , Sun Zhen , Xue Xiu , Pan Yajie , Zhen Shuye , Liu Yang , Zhan Jiuyu , Jiang Linlin , Zhang Jianlong , Zhu Hongwei , Yu Xin , Zhang Xingxiao 
Published: January 2024

IntroductionFeline parvovirus (FPV), a single-stranded DNA virus, is accountable for causing feline panleukopenia, a highly contagious and often lethal disease that primarily affects cats. The epidemiology prevalence and pathogenicity of FPV in certain regions of China, however, remains unclear. The aim of this research was to investigate the epidemiology of FPV in different regions of China in 2021 and compare its infectivity and pathogenicity.MethodsIn this research, a total of 36 FPV strains were obtained from diverse regions across China. Phylogenetic analysis was performed based on the VP2 and NS1 sequences, and two representative strains, FPV027 and FPV072, which belonged to different branches, were selected for comparative assessment of infectivity and pathogenicity.Results and discussionThe results revealed that all strains were phylogenetically classified into two groups, G1 and G2, with a higher prevalence of G1 strains in China. Both in vitro and in vivo experiments demonstrated that FPV072 (G1 group) exhibited enhanced infectivity and pathogenicity compared to FPV027 (G2 Group). The structural alignment of the VP2 protein between the two viruses revealed mutations in residues 91, 232, and 300 that may contribute to differences in infectivity and pathogenicity. The findings from these observations will contribute significantly to the overall understanding of the molecular epidemiology of FPV in China and facilitate the development of an effective FPV vaccine.
Fecal Microbiota and Feeding Habitats of Nomadic Indigenous Animals (Deer, Yak, Sheep and Camel) in Baikal Siberia (Russia)
Authors: Lavrentyeva Elena , Banzaraktsaeva Tuyana , Kozyreva Lyudmila , Danilova Erzhena , Tsyrenova Dulma , Dambaev Vyacheslav , Buryukhaev Savelii , Abidueva Elena , Begmatov Shahjahon , Mardanov Andrey , Barkhutova Darima D. 
Published: January 2024

In the vast expanse of Baikal Siberia, indigenous nomadic animal groups have been conserved, grazing on pastures throughout the year. It is believed that the fecal microbiota of these diverse nomadic animal species is unique to each species and closely tied to their feeding environments. We conducted a pioneering comparative analysis of the taxonomic structure and the diversity of fecal microbiota in indigenous nomadic animals inhabiting Baikal Siberia. Our study encompassed 20 deer, 23 yaks, 24 camels, and 29 sheep, using high-throughput 16S rRNA gene profiling. In the fecal microbiota of these animals, we observed a predominant presence of the phyla Bacillota, Bacteroidota, and Verrucomicrobiota, collectively comprising over 88% of the microbial communities. Moreover, these proportions exhibited variations according to the host species. The unculturable Bacillota UCG-005 and UCG-010 are the key groups for all animals. However, at the genus level, distinctive compositions of fecal microbiota were discernible within each animal group. We identified a total of 37 dominant genera across the fecal samples from these four animal species. Principal component analysis (PCA) and cluster analysis demonstrated that the fecal microbiota composition clustered among individuals of the same animal species. Linear discriminant analysis effect size (LEfSe) indicated that camels exhibited higher abundances of the family Akkermansiaceae and the uncultured clostridial lineage UCG-010, while deer featured Lachnospiraceae; sheep had Ruminococcaceae; and yaks displayed Monoglobaceae, Bacteroidaceae, and methanogenic archaea from the family Methanobacteriaceae as distinctive marker taxa. Our studies showed that the studied nomadic animals feed mainly on plants belonging to the families Poaceae, Cyperaceae, Asteraceae, and Rosaceae. Our research indicated that the identity of the host species and, to a lesser degree, their diets and habitats, significantly shape the composition of fecal microbiota in these studied nomadic ruminant animals.
Pengaruh Partisipasi, Tekanan Anggaran, dan Faktor-Faktor Organisasi Terhadap Kinerja Manajerial KAI
Authors: Ayu Ningsih Dinda , Fitriasuri  
Published: January 2024

Tujuan dari penelitian ini adalah untuk mengetahui pengaruh partisipasi anggaran, tekanan anggaran, asimetri informasi, komitmen organisasi, dan profesionalisme terhadap kinerja manajerial. Penelitian ini menggunakan metode kuantitatif. Populasi dalam penelitian ini adalah seluruh staf manajerial PT. Kereta Api Indonesia (Persero) Divre III Palembang yang berjumlah 66 orang. Sampel yang digunakan diambil secara purposive sampling atau diambil berdasarkan kriteria. Teknik analisis yang digunakan adalah analisis regresi linear berganda. Hasil penelitian menunjukkan bahwa (1) Pengaruh X1 terhadap Y adalah 0,000 < 0,05 dan nilai t hitung 4,693 > t tabel 2,0003, berarti terdapat pengaruh X1 terhadap Y, (2) pengaruh X2 terhadap Y adalah 0.000 < 0.05 dan nilai t hitung 4,175 > t tabel 2,0003, berarti terdapat pengaruh X2 terhadap Y, (3) pengaruh X3 terhadap Y adalah 0,000< 0,05 dan nilai t hitung 3,244 > t tabel 2,0003, berarti terdapat pengaruh X3 terhadap Y, (4) pengaruh X4 terhadap Y adalah 0,22 > 0,05 dan nilai t hitung 2,360 > t tabel 2,0003, berarti terdapat pengaruh X4 terhadap Y, (5) pengaruh X5 terhadap Y adalah 0,000 < 0,05 dan nilai t hitung 14,962 > t tabel 2,0003, berarti terdapat pengaruh X5 terhadap Y.
Kata kunci: Partisipasi Anggaran, Tekanan Anggaran, Asimetris Informasi, Komitmen Organisasi Dan Profesionalisme , Kinerja Manajerial
Isquemia anastomótica por bevacizumab. Casos Clínicos
Authors: Cortes Fuentes Victor Julio Alejandro , Diaz Beneventi Mauricio Javier , Llanos Bravo Jose Luis 
Published: January 2024

Objetivo: Presentar dos casos de isquemia anastomótica tardía por bevacizumab y compararlo con la literatura actual.Casos clínicos: Se exponen dos pacientes con cancer de recto metastásico, con manejo neoadyuvante, quirúrgico y adyuvancia que incluye bevacizumab, que presentan complicaciones isquémicas anastomóticas, evidenciadas con endoscopia, imágenes más biopsias dirigidas, resolviéndose en forma quirúrgica y biopsiando sitios perianastomóticos con cambios isquémicos. Discusión: Existe evidencia en la literatura que reporta isquemias y filtraciones anastomóticas tardías con el uso de bevacizumab. Parece prudente considerar y sospechar en forma oportuna esta complicación, especialmente en pacientes con factores de riesgo.Conclusiones: Se debe considerar eventos isquémicos en territorios quirúrgicos, al uso de Bevacizumab. Mayor hincapié en pacientes con factores de riesgo como malnutrición, irradiación o sexo masculino. Considerar estudio dirigido anastomótico previo al inicio de bevacizumab. Dar relevancia a los tiempos de suspensión y reinicio de bevacizumab para evaluación de posibles complicaciones isquémicas.
Percepción e impacto en la confianza de los residentes de cirugía general de un curso de anastomosis intestinal abierta en un ambiente simulado.
Authors: Cruz Mackenna Enrique , Morales Palma Álvaro José , González Arestizábal Tomás , Valenzuela Silva Diego José , Csendes Juhasz Attila 
Published: January 2024

Objetivo: Evaluar el impacto de un curso de anastomosis intestinal abierta simulada en residentes de cirugía general.Materiales y métodos: Estudio prospectivo no aleatorizado. Se aplicó un curso para residentes del programa de cirugía general del Hospital Clínico Universidad de Chile en 2021 en su primera versión y una segunda vez en 2022. Se evaluó la percepción y confianza con encuestas pre y post curso.Resultados: Participaron diecisiete residentes. De ellos, 16 residentes habían asistido previamente en la técnica básica, 10 nunca habían realizado una anastomosis intestinal a un paciente real como primer cirujano, en su mayoría residentes de segundo y tercer año. El nivel de confianza promedio para realizar una anastomosis intestinal en pacientes previo al curso fue de 1,86/7, 3/7 y 5,38/7 para el primer, segundo y tercer año, respectivamente. De manera global, previo al curso, los residentes promediaron una confianza de 3,09/7.Después del curso, 15/16 residentes estuvieron de acuerdo o muy de acuerdo en que mejoró la confianza en la técnica; que el modelo representa correctamente la situación real, y que los modelos simulados son más efectivos para el aprendizaje que la experiencia clínica por sí sola.Los residentes aumentaron su confianza en 2,47 puntos, alcanzando un promedio de 5,56/7 para la técnica (p=0,001).Conclusiones: El curso de anastomosis intestinal abierta es percibido por los residentes como efectivo, realista y aumenta significativamente la confianza en la realización de esta técnica.
Effectiveness of Online Mediation Application on Divorce Cases Due to Economic Factors
Authors: Mursyid Besse Tenri Abeng 
Published: January 2024

Data from the Religious Courts Class 1A Palu City reports of lawsuits from January to February 2021 were 289 cases. The Covid-19 pandemic has made the divorce rate increase. The reason is that the causes of divorce during the Covid-19 pandemic, on average, have increased in all regions in Indonesia; it is not the case that divorce is caused by family economic factors that are getting worse. The issuance of the Circular Letter of the Supreme Court Number 1 of 2020 concerning Guidelines for the Implementation of Duties During the Prevention of the Spread of Covid-19 in the Supreme Court and the Judicial Body. One of the implementations of mediation that is often carried out conventionally is now carried out online because of conditions that force the court so that every party seeking justice is still given services, observing the problems faced in mediating as a step to find a solution in a divorce lawsuit at the Religious Court Class 1A City. Palu, this study will examine the rules of the Supreme Court Decision Number 10 of 2016 concerning Mediation Procedures and see Empirical Facts on the Implementation of Online Mediation carried out at the Class 1a Religious Court of Palu City. This study's results indicate that online mediation implementation is still carried out within the stages described in the rules for implementing conventional mediation. However, online mediation brings together the parties that rely heavily on internet connections. As well as related to the effectiveness of its implementation, the authors consider this to be less effective because based on the theory of Legal Effectiveness, it shows one indicator, namely the Legal Factor, in this case, the rules that form the basis for the implementation of mediation are not only guided by the Supreme Court Circular Number 10 of 2016 concerning mediation (conventional) so that law enforcement officers, in this case, the Mediator at the Religious Court Class 1a Palu City are reluctant to carry out Online Mediation. As an implication of this research, it is stated that it is necessary to make laws and regulations that specifically regulate the implementation of mediation both conventionally and online, as well as the need for socialization among parties seeking justice to understand the importance of implementing Online Mediation.