bluuebunny/crossref_metadata_2025_split huggingface dataset:
Profiles of Family Stressors Among Low-Income Families with Young Children
Authors: Justice Laura M. , Singletary Britt , Jiang Hui , Schmeer Kammi K. 
Published: February 2025

Abstract

Objectives
This study examined profiles of family stressors, based on the five dimensions of the Family Stress Model (economic hardship, economic pressure, parental psychological distress, interparental relationship problems, and disrupted parenting) among low-income families with young children. We aimed to validate the model with a sample of low-income families and then to determine whether there were reliable profiles of families on the five dimensions.

Methods
Mothers completed questionnaires when children were between six and 15 months old to capture background information and 14 key indicators of the five Family Stress Model dimensions. Our analytical sample comprised 353 families that provided data for at least one key indicator. We conducted confirmatory factor analysis (CFA) to statistically validate the Family Stress Model, then explored distinct profiles using latent profile analyses (LPA), and examined how profile membership correlated with family characteristics.

Results
CFA model fit indices indicated a good fit of the data relative to the theoretical model. LPA revealed three distinct profiles of stressor among families, consistent with low, medium, and high patterns of stressors. Families in the high-stress profile experienced larger household numbers, higher maternal loneliness, reduced social connectedness, and higher reports of unplanned pregnancy.

Conclusions for practice
Findings show applicability of the Family Stress Model to low-income families with young children, and indicate that these families are diverse in terms of the stressors they experience, characterized by three distinct profiles. In this regard, low-income families should not be viewed monolithically, but rather as experiencing variability in the stressors they face.
Simulation based composite likelihood
Authors: Rimella Lorenzo , Jewell Chris , Fearnhead Paul 
Published: February 2025

Abstract
Inference for high-dimensional hidden Markov models is challenging due to the exponential-in-dimension computational cost of calculating the likelihood. To address this issue, we introduce an innovative composite likelihood approach called “Simulation Based Composite Likelihood” (SimBa-CL). With SimBa-CL, we approximate the likelihood by the product of its marginals, which we estimate using Monte Carlo sampling. In a similar vein to approximate Bayesian computation (ABC), SimBa-CL requires multiple simulations from the model, but, in contrast to ABC, it provides a likelihood approximation that guides the optimization of the parameters. Leveraging automatic differentiation libraries, it is simple to calculate gradients and Hessians to not only speed up optimization but also to build approximate confidence sets. We present extensive empirical results which validate our theory and demonstrate its advantage over SMC, and apply SimBa-CL to real-world Aphtovirus data.
Who is the Broker Matters: How Publics Respond to Crisis Related Cross-Sector Networks on Social Media?
Authors: Sun Jingyi , Yang Aimei 
Published: February 2025

Abstract
Multi-organizational cross-sector partnerships on social media involving nonprofits, governments, and corporations are increasingly important for addressing complex social issues. Such large-scale cross-sector networks would not be possible without brokers who connect otherwise disconnected clusters. Nevertheless, cross-sector brokers are not always positively received by the public. Drawing from the brokerage typology literature, we classify five distinctive types of brokers (i.e., representative, gatekeeper, liaison, itinerant, and coordinator) and explore public responses associated with them, and how such effects spill over to connected same-sector organizations. Our findings show that different types of brokers receive different public responses, which are moderated by organizations’ sectors. In particular, nonprofits playing brokerage roles are more likely to be positively received by the public compared to government agencies.
Synthesis of titania/activated carbon composites for the synergistic adsorption and photocatalysis of lindane in aqueous solutions
Authors: Stavrinou Anastasia , Theodoropoulou Maria A. , Tsakiroglou Christos D. 
Published: February 2025

Abstract
Lindane (LIND) is an organochlorine pesticide, belonging to the persistent organic pollutants (POPs), which are bioaccumulative with detrimental effects on human health and environment. In the present work, activated carbon (AC) produced from coffee waste after activation with sodium hydroxide (NaOH) and pyrolysis at 800 °C (CWAC-NaOH-800) is tested as adsorbent of LIND, and as substrate for the synthesis of hybrid adsorbent/photocatalytic materials of titanium oxide with activated carbon (TiO2/AC) via the sol–gel method, aiming at the synergistic adsorption and photocatalysis of LIND. Three different TiO2/AC materials were synthesized at mass ratio of TiO2 to AC equal to 2.0 (material TiO2/AC-0.2), 4.0 (material TiO2/AC-0.1), and 8.0 (material TiO2/AC-0.05). As the TiO2 to AC mass ratio increases, the specific surface area and total pore volume of the composite materials decrease, the meso-/macro-porosity are reduced and a pore-and-throat microporous network is created within the agglomerates of TiO2 nanoparticles. The adsorption of LIND onto the CWAC-NaOH-800 is pH-independent and follows the Langmuir model with a maximum adsorption capacity equal to 9.74 mg/g. The adsorption mechanism is likely to be the hydrophobic interactions as generally ACs tend to repel water molecules and preferentially adsorb non-polar or hydrophobic compounds such as LIND. The mass transfer multi-compartment model was used to describe the LIND sorption dynamics in CWAC-NaOH-800 and TiO2/AC-0.1, by accounting for the film/pore/surface diffusion and instantaneous linear sorption, and it was found that the contribution fraction of surface diffusion and microporosity to the total LIND sorption was enhanced with the presence of TiO2, due to the decrease of meso-/macro-porosity. For the study of the adsorptive-photocatalytic capacity of composite materials, two experimental setups were tested and compared: an ultraviolet-A (UVA) oven with LEDs (power = 22 W, λ = 375 nm) radiating from the periphery to the center of the reactor, and a UVA lamp (power = 6 W, λ = 375 nm) radiating radially from the center to the reactor walls. The material TiO2/AC-0.1 showed LIND sorption capacity comparable to that of CWAC-NaOH-800 and photocatalytic performance better than that of TiO2 nanoparticles, due to the presence of AC and the “co-adsorption” effect. During the synergistic adsorption-photocatalysis process, the TOC removal efficiency reached 90% after 3 h of photocatalysis, which is indicative of the in situ regeneration of the material. From the inverse modeling of the adsorption-photocatalysis experiments, it was found that the kinetic constant of TiO2/AC-0.1 photocatalyst was highest in the experimental setup of the UVA lamp, showing a good balance between adsorptive and photocatalytic capacity.

Graphical abstract
Using gesture recognition with the memory strategy to improve preschoolers’ learning performance, motor skills, and executive function
Authors: Hsiao Hsien-Sheng , Chang I-Hsiung , Chen Yi-Hsuan , Chen Jyun-Chen 
Published: February 2025

Abstract
Gesture recognition can create an interactive environment in which to train children to control their thoughts, gestures, and body postures when performing learning activities. This study integrated gesture recognition and a memory strategy to develop a physical learning activity for preschoolers to improve their English learning performance, motor skills (namely, stability and movement), and executive functions (namely, working memory). The study selected 67 kindergarten level 3 preschoolers. They were divided into either the experimental group (gesture recognition with memory strategy) or the control group (traditional activity learning with memory strategy). The experiment was conducted over a period of six stages for a total duration of 360 min. The results showed that the participants who used gesture recognition with the memory strategy demonstrated better learning performance, motor skills, and executive functions, and the statistics showed a significant deviation between the two approaches. With gesture recognition, the instructor enhanced the learning process of the children’s physical motions and cognitive knowledge by strengthening the connection between life experiences and specific tasks, and the children’s executive functions also improved. The research contribution of this study is a pedagogy manuscript for teachers who want to create a physical activity with gesture technology for preschoolers.
Hydraulic erosion mitigation in sandy soil using cation-crosslinked gelation biopolymer
Authors: Lee Minhyeong , Chang Ilhan , Cho Gye-Chun 
Published: February 2025

Abstract
The increasing frequency of geotechnical disasters and climate-related land degradation underscores the need of resilient soil erosion mitigation. This study investigates the effectiveness of Cr3+-crosslinked xanthan gum (CrXG), a cation-crosslinked gelation biopolymer with time-dependent gelation and water-resistant properties, in mitigating hydraulic soil erosion. Through the erosion function apparatus test, rheological analysis, and microscopic observations, results indicate notable improvements in soil erosion resistance with CrXG treatment, elucidating distinct reinforcing mechanisms attributable to the gel state of the biopolymer hydrogel. The addition of 0.25% CrXG to the soil mass significantly improves critical shear stress and critical velocity, reducing the erodibility coefficient by four order magnitudes compared to untreated sand. Within 48 h, the transition from a viscous to rigid gel state in CrXG, driven by cation crosslinking, transforms the soil from high (II) to low (IV) erodibility class. Scour predictions using the program, based on river hydrograph conditions, indicate a substantial delay in reaching a 1-m scour depth. This study highlights CrXG-soil composite’s potential as an advanced geomaterial for mitigating geohazards such as floods and stream scouring, while offering insights into its competitiveness with conventional soil stabilization techniques.
Roles of Market Characteristics and Experience in Ventures’ International Growth Mode Choice: A Conjoint Experiment
Authors: Ego Philipp , Pidun Ulrich 
Published: February 2025

Abstract
This study investigates the decision criteria that entrepreneurs apply when choosing growth modes to internationalize their business. Specifically, we examine how market characteristics and experience impact the selection of organic, acquisitive, or collaborative growth strategies. Data on 1,080 mode decisions were collected in conjoint experiments and analyzed using hierarchical multinomial logistic regression. We find that barriers to entry and competitive intensity are the most determining market factors, and that international and mode-related experiences have considerable moderating effects. Our findings indicate that imitative behavior and normative preferences are less prevalent in entrepreneurial than in corporate decision-making.
Impact of Pre-Existing Disability on Long-Term Health Care Use Following Hospitalization for COVID-19: A Population-Based Cohort Study
Authors: Brown Hilary K. , Stukel Thérèse A. , Chung Hannah , Lee Samantha , Lunsky Yona , Bell Chaim M. , Bobos Pavlos , Cheung Angela M. , Detsky Allan S. , Goulding Susie , Herridge Margaret , Razak Fahad , Verma Amol A. , Quinn Kieran L. 
Published: February 2025

Abstract

Background
Emerging evidence shows the lasting impact of SARS-CoV-2 infection on health care use and needs. Policy-makers require data on population-level service use to understand patient needs and health system impacts following hospitalization for COVID-19.

Objective
To compare health service use within 12 months following hospitalization for COVID-19 among people with and without pre-existing disabilities, and to determine the extent to which such use is related to disability and other risk factors.

Design
Population-based cohort study, Ontario, Canada.

Participants
Adults with and without disabilities hospitalized for COVID-19, 01/25/2020–02/28/2022.

Main Measures
We used Poisson regression to model adjusted rate ratios (aRR) of ambulatory care visits, diagnostic testing, emergency department (ED) visits, hospital admissions, and palliative care visits within 1-year post-discharge, comparing patients with and without disabilities. Models were adjusted sequentially for sociodemographic factors, comorbidities, and prior health service use. The importance of each set of covariates in its ability to explain observed associations was determined by calculating relative changes in disability parameter coefficients after each sequential risk-adjustment.

Key Results
The cohort included 25,320 patients with disabilities and 15,953 without. In the year after hospitalization for COVID-19, people with disabilities had higher rates of ambulatory care visits, diagnostic tests, ED visits, hospital admissions, and palliative care visits. A significant proportion of these associations was explained by sociodemographic factors, comorbidities, and prior health service use. However, adjusted relative rates associated with disability remained elevated, even after adjustment, for ambulatory care visits (aRR 1.09, 95% CI 1.08, 1.10), diagnostic tests (aRR 1.14, 95% CI 1.12, 1.16), ED visits (aRR 1.25, 95% CI 1.21, 1.29), and hospital admissions (aRR 1.21, 95% CI 1.16, 1.29).

Conclusions
These findings support the need to develop and evaluate models of care for the post-COVID-19 condition that address the needs of people with disabilities.
Training International Medical Graduate Internal Medicine Residents in Pelvic Examinations and Pap Smears
Authors: Swedish Kristin A. , Tyau Nicholas D. , Icitovic Nikolina , Metalios Eva E. 
Published: February 2025

Abstract

Background
Nearly 39% of Internal Medicine (IM) residents in American training programs are international medical graduates (IMGs), whose prior training in women’s health is variable. There is a paucity of data about women’s health training programs that train IMG IM residents in pelvic examinations/Pap smears.

Aim
To train IMG IM residents to competently perform pelvic examinations/Pap smears.

Setting
Montefiore Wakefield IM residency clinic, Bronx NY.

Participants
IMG categorical IM residents.

Program Description
In 2015, we established the Women’s Health Clinic (WHC) to train residents in pelvic examinations/Pap smears. The educational model includes one hour of didactics followed by trainees seeing up to four patients, supervised by WHC faculty in 1:2 preceptor to resident ratio.

Program Evaluation
We evaluated the impact of WHC on IMG residents’ self-reported competence in performing pelvic examinations/Pap smears by using McNemar’s test to compare self-reported competence in pelvic examinations and Pap smears before and after WHC participation.

Discussion
WHC improved self-reported competence among IMG residents by utilizing standardized didactics reinforced through immediate and repeated patient interactions. It is an educational model that could be reproduced by other IM programs to improve training for IMG residents.
Review: An Update on CGRP Monoclonal Antibodies for the Preventive Treatment of Episodic Migraine
Authors: Nicol Kelly S , Burkett John G 
Published: February 2025

Abstract

Purpose of Review
CGRP targeting therapies have revolutionized the migraine preventive space, introducing novel migraine-specific therapies to improve headache care. Four monoclonal antibodies (mAbs) are approved for use in prevention of episodic migraines. Erenumab (AMG334), fremanezumab (TEV48125), and galcanezumab (LY2951742) are monthly subcutaneous injections, while eptinezumab (ALD403) provides an intravenous infusion option. This review aims to examine the clinical evidence for the safety and efficacy of CGRP-targeted mAbs in the prevention of episodic migraines with a focus on recent studies (2023–2024).

Recent Findings
Long-term studies reveal ongoing safety and efficacy in recent literature for all 4 monoclonal antibodies. These investigations have built evidence for earlier access to CGRP treatment as they increase quality of life and reduce monthly migraine days while being better tolerated than non-specific migraine preventative therapies.

Summary
These studies support the recent 2024 AHS consensus statement recommending CGRP monoclonal antibodies be considered as first-line preventive treatment in episodic migraine.
Management and outcome of children with high-risk neuroblastoma: insights from the Spanish Society of Pediatric Hematology and Oncology (SEHOP) neuroblastoma group on refractory and relapse/progressive disease
Authors: de las Heras Blanca Martínez , Rubio-Aparicio Pedro M , Rubio-San-Simón Alba , Moreno Lucas , Mazorra Paula , Almaraz Ricardo López , López Mercedes Llempén , Guill Julia Balaguer , Segura Vanessa , Bermúdez Mar , Jiménez Irene , Ramal Désirée , Cañete Adela 
Published: February 2025

Abstract

Purpose
Outcome for children with refractory and relapse/progressive high-risk neuroblastoma (HR-NB) remains poor, without an internationally agreed standard second-line approach. Heterogeneity in patients’ disease and treatment strategies challenges clinical management. The survival rate for patients with resistant disease does not exceed 20% at 5 years. The study’s aim was to analyze refractory and progressive HR-NB patients in a real-world setting to evaluate current clinical practices and optimize future approaches.

Methods
Data from patients diagnosed with refractory and relapse/progressive (R/R-P) HR-NB between January 2019 and December 2021 at six of the major Spanish neuroblastoma treating hospitals were collected and analyzed.

Results
A total of 67 episodes of R/R-P HR-NB were included. Treatments applied included chemotherapy (97%), immunotherapy (48%), consolidation (21%), local treatment (surgery and/or radiotherapy) (45%) and maintenance (16%), and were administered within a clinical trial (CT) in 34% of the episodes. Biopsy was performed in 37% of the tumors and 30% were profiled. Event-free survival (EFS) in our cohort was 20.9% and overall survival (OS) 32%. Significant survival advantage (in both OS and EFS) was observed in refractory episodes compared to relapse/progressive, in first events compared to successive, and when response or disease stabilization was achieved. MYCN status, presence of lymph node metastases, use of irinotecan or topotecan, and radiotherapy were also univariate predictors of OS.

Conclusions
Treatment of refractory and relapse/progressive HR-NB is highly heterogeneous. We confirm a poor outcome, although certain epidemiological and treatment-related factors have prognostic value. Molecular profiling and inclusion in CTs should be improved.
Cognitive emotion regulation strategies and academic burnout dimensions in children and adolescents: a network analysis approach
Authors: Iuga Ioana Alexandra , Fodor Liviu Andrei , David Oana Alexandra 
Published: February 2025

Abstract
Students experience high levels of academic stress associated with exams, the interaction with teachers, bullying, and parental consequences associated with failure in the academic context. An important question is how can certain people manage stressful academic situations efficiently, whereas other people struggle, eventually developing mental health problems such as academic burnout. Our main objective is to identify how different academic burnout dimensions are interconnected and associated with cognitive emotion regulation strategies (CERS). A secondary objective was to investigate whether the network changes its connectivity across genders. The sample consisted of 710 Romanian youth aged 9-16 (M = 10.67). Networks were estimated using the Gaussian graphical model. Further, we employed a network subgroup analysis in order to test for statistically significant differences between the networks for females and males, respectively. Our results identified emotional exhaustion and cynicism as main dimensions of academic burnout, and catastrophizing and reappraisal as main CERS in the network structure. In terms of important links within the network, the relationship between exhaustion and cynicism, followed by the relationship between exhaustion and inadequacy, self-blame and catastrophizing, and positive reappraisal and refocus on planning was emphasized. There were no statistically significant differences of global strength and edge weights across the networks, although several differences emerged in terms of individual edge differences. Following additional replication of our findings, future prevention and intervention programs should focus on cognitive strategies that would target catastrophizing and train reappraisal strategies in stressful academic settings.
Stopping bosutinib reverses bosutinib-induced elevation of serum creatinine in patients with chronic myeloid leukemia
Authors: Abumiya Maiko , Saito Ayano , Fujioka Yuki , Miura Masatomo , Takahashi Naoto 
Published: February 2025

Abstract
Bosutinib is known to increase serum creatinine levels, and its mechanism of action is believed to involve a decrease in tubular creatinine excretion due to inhibition of tubular transporters and organic cation transporter 2. This study aimed to determine whether discontinuation of bosutinib could reverse bosutinib-induced elevation of serum creatinine levels. Serum creatinine levels were compared immediately before and after bosutinib administration and after bosutinib discontinuation in 11 patients with chronic myeloid leukemia. The median serum creatinine concentration significantly increased from 0.66 mg/dL before bosutinib to 0.76 mg/dL after bosutinib (P = 0.003) and decreased from 0.79 mg/dL before discontinuation of bosutinib to 0.66 mg/dL after discontinuation of bosutinib at 3 months (P = 0.005). This study revealed that bosutinib-induced elevation of serum creatinine, which was more pronounced in patients with the SLC22A2 808G/G genotype, does not indicate chronic kidney disease, but rather is simply a laboratory abnormality. If bosutinib-induced chronic kidney disease is suspected, renal function should be assessed by urinalysis and cystatin C levels to differentiate from simple elevation of serum creatinine.