bluuebunny/crossref_metadata_2025_split huggingface dataset:
Depletion of tilmicosin residue in Gushi chickens following oral administration via drinking water
Authors: Zhang Mei , Qian Kun , Li Guang‐Hui , Duan Ming‐Hui , Li Ze‐En , Dai Yan , Chen Jun‐Cheng , Yang Fan 
Published: November 2023

AbstractThis study aimed to examine the depletion of tilmicosin residues in Gushi chickens following the administration at a concentration of 75 mg/L in their drinking water for three consecutive days. Plasma, liver, kidney, lung, muscle, and skin + fat samples were collected from 6 chickens at 6 h, 1, 3, 5, and 7 days after the treatment. Tilmicosin concentrations in the samples were determined using a high‐performance liquid chromatography (HPLC) method. The findings revealed that the highest tilmicosin residues were detected in the liver, followed by the kidney, lung, skin + fat, muscle, and plasma. Notably, at 7 days post‐treatment, no drug residue was detected in all samples except for the liver and kidney. The non‐compartmental model was employed to calculate relevant pharmacokinetic parameters. The elimination half‐lives (t1/2λz) of tilmicosin were as follows, ranked from long to short: skin + fat (45.42 h), liver (44.17 h), kidney (40.06 h), plasma (37.64 h), lung (31.39 h), and muscle (30.05 h). Considering the current residue depletion and the maximum residue limits (MRLs) set by Chinese regulatory authorities, the withdrawal times for tilmicosin were estimated as 18.91, 10.81, and 8.58 days in the kidney, liver, and skin + fat, respectively. A rounded‐up value of 19 days was selected as the conclusive withdrawal time. Furthermore, based on the observed tilmicosin concentrations in plasma and lung, combined with previously reported minimum inhibitory concentration (MIC) values against Mycoplasma gallisepticum, the current dosing regimen was deemed adequate for treating Mycoplasma gallisepticum infections in Gushi chickens.
Sensory evaluations of a novel iron and zinc‐enriched powder for the potential treatment and prevention of iron deficiency in women of reproductive age
Authors: Miller Clara H. , Sheyholislami Hauna , Burns Jessie L. , Connor Kristin L. 
Published: November 2023

AbstractIron deficiency (ID) and ID with anaemia (IDA) are serious global health problems that disproportionately affect women aged 15–49 years. Although food fortification is one of the most effective and sustainable ways to combat nutritional deficiencies, iron remains one of the most difficult micronutrients to fortify, given its tendency to react strongly with food constituents. Therefore, it is important to assess the sensory properties of foods fortified with iron to determine the acceptability and palatability in target populations. We aimed to determine the palatability and acceptability of a novel iron and zinc‐enriched powder fortified in tap water by conducting sensory evaluations in 35 women of reproductive age using a 9‐point hedonic scale, where participants rated the sensory properties of six samples containing different amounts of the active or placebo powder. We found significant differences between samples reconstituted at 1, 2, and 3 g/L for sensory properties, including overall taste. Participants were found to be more willing to drink the mineral‐enriched powder when prepared at the lowest concentration (1 g/L) compared to higher concentrations. Our results provide important insight into the sensory qualities of a novel formulation of an iron and zinc‐enriched powder for at‐home fortification and indicate consumer acceptability in reproductive‐aged women, a key group at risk for ID/IDA. If found to improve iron status, novel treatments like this product will contribute to global efforts to develop safe, acceptable and sustainable interventions for ID and IDA.
Paraneoplastic cerebellar degeneration after improvement of Lambert–Eaton myasthenic syndrome
Authors: Hirosawa Hiroaki , Maesaka Hiroki , Matsuda Noriyuki , Nukui Takamasa , Nakane Shunya , Nakatsuji Yuji 
Published: November 2023

AbstractA 57‐year‐old man presented with progressive muscle weakness in the lower limbs, with elevated anti‐P/Q‐type voltage‐gated calcium channel antibody levels. A repetitive stimulation test showed waxing with high‐frequency stimulation. He was diagnosed with Lambert–Eaton myasthenic syndrome (LEMS) and small‐cell lung cancer. After four courses of cisplatin and etoposide, computed tomography showed a decrease in tumor size and muscle weakness improved. After 3 months, the patient presented with progressive ataxic gait and dysarthria and was admitted to our hospital. Magnetic resonance imaging revealed slight cerebellar atrophy. We diagnosed the patient with paraneoplastic cerebellar degeneration (PCD)‐LEMS. The patient received intravenous immunoglobulin therapy, steroid pulse therapy, and plasmapheresis. The patient's cerebellar ataxia then improved. This represents a rare case of PCD‐LEMS after improvement of LEMS.
Exploring communication apprehension in nursing and healthcare education: A scoping review
Authors: Schulenberg Shannon , Oh Kyeung Mi , Goldberg Debora G. , Kreps Gary L. 
Published: November 2023

AbstractCommunication among healthcare professionals is critical to optimizing patient outcomes, and communication education is incorporated into the educational programs of healthcare professions students. Communication can be a source of stress for new healthcare professionals, however, there is a lack of research on communication apprehension (CA) in healthcare students, especially in nursing education. This scoping review sought to explore CA and factors associated with CA among healthcare professions students. This scoping review report was guided by the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses extension for Scoping Reviews (Tricco et al., Annals of Internal Medicine, 2018, 169, 467–473). Twenty studies of healthcare professions students were included for analysis. The percentage of health professions students with high CA ranged from 0.7% to 27%. Five out of seven intervention studies demonstrated a significant decrease in CA after the intervention. This review identified inconsistent associations between CA and various individual and educational factors. More research is needed utilizing rigorous research designs, designs employing qualitative methodology, and studies to investigate the impact of language on CA in health professions students who speak English as a second language.
Phosphoproteome analyses pinpoint the F‐box protein SLOW MOTION as a regulator of warm temperature‐mediated hypocotyl growth in Arabidopsis
Authors: Zhu Shanshuo , Pan Lixia , Vu Lam Dai , Xu Xiangyu , Orosa‐Puente Beatriz , Zhu Tingting , Neyt Pia , van de Cotte Brigitte , Jacobs Thomas B. , Gendron Joshua M. , Spoel Steven H. , Gevaert Kris , De Smet Ive 
Published: November 2023

Summary
Hypocotyl elongation is controlled by several signals and is a major characteristic of plants growing in darkness or under warm temperature. While already several molecular mechanisms associated with this process are known, protein degradation and associated E3 ligases have hardly been studied in the context of warm temperature.
In a time‐course phosphoproteome analysis on Arabidopsis seedlings exposed to control or warm ambient temperature, we observed reduced levels of diverse proteins over time, which could be due to transcription, translation, and/or degradation. In addition, we observed differential phosphorylation of the LRR F‐box protein SLOMO MOTION (SLOMO) at two serine residues.
We demonstrate that SLOMO is a negative regulator of hypocotyl growth, also under warm temperature conditions, and protein–protein interaction studies revealed possible interactors of SLOMO, such as MKK5, DWF1, and NCED4. We identified DWF1 as a likely SLOMO substrate and a regulator of warm temperature‐mediated hypocotyl growth.
We propose that warm temperature‐mediated regulation of SLOMO activity controls the abundance of hypocotyl growth regulators, such as DWF1, through ubiquitin‐mediated degradation.
Mana Wahine reworking the power to name taonga
Authors: Ringham Sandi 
Published: November 2023

AbstractThe capacity of Indigenous peoples to officially name taonga species (flora and fauna) within taxonomy signifies resilience and a reworking of western scientific processes and institutions. This article explores the ways in which Ngāti Kuri women contribute to environmental justice through the naming of taonga species. Ngāti Kuri were the first tribe in the world to install a tribal name into the co‐authorship of a nomenclature. The article explores the ways in which Ngāti Kuri women, both past and present, rework environmental relationships and knowledge in both tribal and non‐tribal spaces in Aotearoa's most northern region.
A novel homozygous splice‐site mutation of JK gene leads to Jk(a‐b‐) phenotype
Authors: Yang Jiaxuan , Ni Lina , Li Aijing , Li Minghao , Ruan Shulin , Xiang Dong , Zhu Ziyan , Ye Luyi 
Published: November 2023

AbstractObjectivesThis study aimed to investigate the molecular mechanism of the Jk(a‐b‐) phenotype in a Chinese transfusion patient.BackgroundMany different mutation types relating to Jk(a‐b‐) phenotype have been reported. However, the splice‐site mutation is relatively rare and the related functional verification is lacking.Materials and MethodsIn this study, the blood sample was collected from a transfusion patient with the Jk(a‐b‐) phenotype. Serotyping was performed using routine serological methods. The exons sequences and coding regions of the JK gene were amplified using polymerase chain reaction and directly sequenced. To perform a minigene splicing assay, the intronic mutation sequences were cloned into a pSPL3 splice reporting vector. The splicing reporter minigene assay was performed in HEK 293T cells.ResultsThe Jk(a‐b‐) phenotype of the blood sample was identified through serological testing. Sequencing results revealed that the sample had a novel homozygous splice‐site mutation JK*02N (NM_015865.7: c.663+3A>C). Further analysis, including cDNA sequencing and minigene splicing assay, confirmed that the novel splice‐site mutation resulted in exon skipping. Interestingly, different numbers of exons being skipped were obtained by the two methods.ConclusionThis study revealed a novel homozygous splicing‐site mutation associated with the Jk(a‐b‐) phenotype in Chinese population. Our results emphasise the importance of the in vitro functional method minigene splicing assay, while also acknowledging its potential limitations when compared to cDNA sequencing.
Autumn Migration of Greater Noctule Bat (Nyctalus Lasiopterus): through Countries and over Mountains to a New Migration Flight Record in Bats
Authors: Vasenkov D. A. , Vasiliev N. S. , Sidorchuk N. V. , Rozhnov V. V. 
Published: November 2023

Abstract—
For the first time, using GPS-GSM trackers, long-term seasonal flights of greater noctule bat (Nyctalus lasiopterus) from summer habitats in Russia to wintering areas in Europe are recorded. One of the seasonal migratory flights is a record distance for bats (2515 km). The maximum daily flight was 445 km. One of the animals abruptly changed the direction of migration from southwest to north on the third day of flight after crossing the Kursk magnetic anomaly.
Elastic properties and mechanical stability of bilayer graphene: molecular dynamics simulations
Authors: Herrero Carlos P. , Ramírez Rafael 
Published: November 2023

Abstract
Graphene has become in last decades a paradigmatic example of two-dimensional and so-called van-der-Waals layered materials, showing large anisotropy in their physical properties. Here, we study the elastic properties and mechanical stability of graphene bilayers in a wide temperature range by molecular dynamics simulations. We concentrate on in-plane elastic constants and compression modulus, as well as on the atomic motion in the out-of-plane direction. Special emphasis is placed upon the influence of anharmonicity of the vibrational modes on the physical properties of bilayer graphene. We consider the excess area appearing in the presence of ripples in graphene sheets at finite temperatures. The in-plane compression modulus of bilayer graphene is found to decrease for rising temperature, and results to be higher than for monolayer graphene. We analyze the mechanical instability of the bilayer caused by an in-plane compressive stress. This defines a spinodal pressure for the metastability limit of the material, which depends on the system size. Finite-size effects are described by power laws for the out-of-plane mean-square fluctuation, compression modulus, and spinodal pressure. Further insight into the significance of our results for bilayer graphene is gained from a comparison with data for monolayer graphene and graphite.

Graphic abstract
Revisiting the Plantation Society: The New World Group and the Critique of Capitalism
Authors: Timcke Scott 
Published: November 2023

Abstract
This paper examines the critique of capitalism provided by the New World Group. Emerging from the West Indian Society for the Study of Social Issues at The University of The West Indies, Mona, the Group was formed in 1963 specifically to address the reconfiguration of social and political forces in the wake of Caribbean territories gaining formal independence from European colonial powers. This reconfiguration went beyond matters of political economy, and included psychological and ideological reworkings, all items necessary to evaluate the kinds of societies West Indians could strive for. Set within intra-Marxist debates on early capitalist development, this paper focuses on the collaboration and creative tensions between Norman Girvan, George Beckford, and Lloyd Best as they helped one another construct their respective political philosophy, social theory, and economic analysis of the logic of plantation societies, which while incomplete from our vantage point, did mostly capture the historical dynamics found in the Caribbean.
Knowing War
Authors: Suchman Lucy 
Published: November 2023

Abstract
This commentary reflects on contributions to the pariss special issue Datawar. My readings highlight the implications of war’s remediations for practices through which it is rendered knowable. Critical engagement with martial epistemologies requires an articulation of the irremediable locatedness and partiality of knowledge practices, and the fallacy of data-solutionism as the latest promise of an end to ‘the fog of war.’ I conclude with some reflections on the possibilities that these writings suggest for counter-knowledges that might further destabilize military logics, to open spaces for modes of relation not based on the violence of claims to omniscience.
A novel three-layer woven fabric composite reinforced by (polyaniline + carbonyl iron) core-shell/carbonyl iron/polyaniline fillers for high-performance broadband radar absorbing structure
Authors: Danesh Mohammad , Beheshti Hamid , Heidari-Rarani Mohammad 
Published: November 2023

One of the most important applications of electromagnetic wave absorption is in stealth aircrafts and electromagnetic protection of avionic systems. The main limitations in the design of these structures are aerodynamics, thickness or weight, mechanical strength, manufacturing process, and reasonable cost. In this study, a novel three-layer woven fabric composite laminate (with a total thickness of about 3 mm) is proposed which each layer is reinforced by individual polyaniline, carbonyl iron, or (PANI + CI) core-shell fillers. The developed Non-dominated Sorting Genetic Algorithm II optimization algorithm suggests the stacking sequence of layers, the appropriate thickness of each layer, and the filler weight fraction in each layer to achieve a broadband absorption. Due to using both dielectric and magnetic absorbing fillers, this structure shows well-impedance matching and approximately absorbs 80% of the X-band (8-12 GHz) electromagnetic waves. The maximum reflection loss is about −14dB. Finally, the effect of the addition of absorbent particles on the mechanical properties has been investigated. Experimental results showed that the tensile modulus and strength decrease by about 21.5% and 20.6%, respectively, and the flexural modulus and strength reduce by 21.7% and 19.7%, respectively. However, the (PANI + CI) core-shell filler can be introduced as a high performance absorber filler because it suggests maximum reflection loss with low weight fraction compared to other fillers and consequently the minimum reduction in mechanical properties.
MYL9 promotes squamous cervical cancer migration and invasion by enhancing aerobic glycolysis
Authors: Wen Bin , Luo Limei , Zeng Zhaoyang , Luo Xiping 
Published: November 2023

Objective This study explored the mechanism of squamous cervical cancer (SCC) progression. Methods Reverse transcription-quantitative polymerase chain reaction and western blotting were used to evaluate the expression of myosin light chain 9 ( MYL9) in SCC tissues and cell lines. Furthermore, Transwell and Boyden assays were used to assess the function of MYL9 in SCC progression. In addition, the levels of lactate and aerobic glycolysis were used to explore the detailed mechanism of MYL9 in SCC. Results The mRNA and protein levels of MYL9 were elevated in SCC tissues, and MYL9 knockdown inhibited the migration and invasion of SCC cell lines. A mechanistic study demonstrated that MYL9 promotes SCC migration and invasion by enhancing aerobic glycolysis and increasing the activity of the Janus kinase 2 (JAK2)/signal transducer and activator of transcription 3 (STAT3) pathway. Conclusions MYL9 was upregulated in SCC, and it enhanced JAK2/STAT3 pathway activity and promoted metastasis and glycolysis in SCC.
Impact of Care-Recipient Relationship Type on Quality of Life in Community-Dwelling Older Adults With Dementia Over Time
Authors: Lai Aiping , Griffith Lauren E , Kuspinar Ayse , Turchyn Jenna-Smith , Richardson Julie 
Published: November 2023

Introduction Maintaining quality of life (QoL) has been identified as the primary goal of care services for person living with dementia (PLWD). Methods A secondary analysis was conducted on five rounds of the National Health and Aging Trends Study (NHATS) over 4 years. A generalized estimating equation (GEE) was used to examine the prediction of relationship type on older adults’ QoL through four domains: mental health, general health, functional limitations, and pain. Results older adults cared for by an adult-child or multiple caregivers predicted increased risk for functional limitations after adjustment for their socio-demographic and dementia status (IRR = 1.53, CI [1.26, 1.86]; IRR = 1.36, CI [1.14, 1.61], respectively). The interaction between the relationship type and education was significant. Older adults with a high school education or below, who were cared for by an adult child, had a significantly higher risk of increasing functional limitations over 4 years compared to those cared for by a spouse/partner (contrast = .50, P = .01, 95% CI [.07, .93]; contrast=.52, P = .03, 95% CI [.03, 1.02]; respectively). Similarly, older adults with a high school education, who were cared for by multiple caregivers, also experienced a significantly higher risk of increasing functional limitations than those cared for by a spouse/partner (contrast = .44, P = .03, 95% CI [.02, .85]). Conclusion Our findings provide evidence of the significant contribution of relationship type on PLWD’s QoL changes over time. They also help to prioritize resource allocation while addressing PLWD’s demands by socio-demographics such as education level.
Acoustic adjustments of clear speech in Korean heritage vowel production
Authors: Chang Seung-Eun 
Published: November 2023

Aims and objectives: This study aims to explore the segmental and suprasegmental acoustic adjustments in the clear speech of Korean vowels produced by English-dominant Korean-heritage speakers and native Korean speakers. Methodology: Native Korean students at a university in the United States and Korean-American students enrolled in an intermediate Korean language course at the same university read isolated sentences featuring three representative Korean vowels (i.e., /i, a, u/), once in casual speech, and once in clear speech. They repeated this sequence five times. Data and analysis: The vowel space of the first and second formants (F1 and F2) in the clear speech was expanded for both heritage and native speakers, and the heritage vowel space was more fronted than the native vowel space, suggesting the influence of English among heritage speakers. However, the peripheral extent and direction in the clear speech and the dominant language effect in heritage speakers were inconsistent across the vowels. Also, pitch dynamics were highly significant in clear speech, exhibiting the salient fundamental frequency (F0) rising at the syllable offset for both heritage and native speakers. The vowel length enhancement in the clear speech was also confirmed in both native and heritage Korean vowels. Conclusions: The results confirmed the cross-language tendency in clear speech to induce the modification of vowel quality, pitch, and duration, which also applies to Korean heritage vowel production. Furthermore, the asymmetrical acoustic modifications across the vowels in heritage clear speech support the Speech Learning Model (SLM) prediction. Originality and implications: The findings present new data for the clear speech effects of Korean heritage vowel production and a further enhancement strategy of syllable offset pitch raising in clear speech for both native and heritage groups. The results contribute to the theoretical implication of bilingualism by connecting the SLM premise and heritage clear speech.