bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pharmacist-Led Diabetes Control Intervention and Health Outcomes in Hispanic Patients With Diabetes
Authors: Narain Kimberly Danae Cauley , Moreno Gerardo , Bell Douglas S. , Chen Lillian , Tseng Chi-Hong , Follett Robert W. , Skootsky Samuel , Mangione Carol M. 
Published: September 2023

ImportanceAmong patients with type 2 diabetes (T2D), Hispanic individuals are more likely than non-Hispanic White individuals to develop diabetes-related complications.ObjectiveTo examine the association of a pharmacist-led intervention (UCMyRx) with hemoglobin A1c(HbA1c) and systolic blood pressure (SBP) among Hispanic patients with T2D.Design, Setting, and ParticipantsThis quality improvement study used electronic health record data and a difference-in-differences study design to evaluate the association of UCMyRx exposure with changes in HbA1cconcentration and SBP among Hispanic patients with T2D, relative to usual care, at University of California, Los Angeles primary care clinics between February and April of 2023. The study population included patients with anInternational Classification of Diseases, Ninth Revision/International Statistical Classification of Diseases and Related Health Problems, Tenth Revisiondiagnosis of T2D, self-reporting Hispanic ethnicity, age 18 years or older, with 1 or more visits with a UCMyRx pharmacist (treatment) or 2 or more visits, 2 or more years apart, during the study window (comparison). Additionally, patients had to have the following observations during the study window (March 2, 2013-December 31, 2018): (1) a HbA1c8% or higher, anywhere between 365 days before and 14 days after the index date (date of the first UCMyRx visit or a randomly generated index date) and a follow-up HbA1cmeasure within 120 to 365 days after the index date (n = 396) and/or (2) a SBP 140 mm Hg or higher between 365 days before and 14 days after the index date, and a follow-up SBP measure within 120 to 450 days after the index date (n = 795).ExposurePharmacists review laboratory results/vital signs, perform medication reconciliation, and develop personally tailored interventions to address adherence barriers and increase guideline-concordant care.Main Outcomes and MeasuresPre– to post–index date changes in HbA1cand SBP.ResultsOf the 931 unique patients with T2D analyzed, the mean (SD) age was 64 (14.1) years, and 552 (59.3%) were female. In adjusted analyses, having 1 or more UCMyRx visits was associated with a reduction in HbA1cconcentration (β = −0.46%; 95% CI, −0.84% to −0.07%) but no change in SBP (β = −1.71 mm Hg; 95% CI, −4.00 to 0.58 mm Hg).Conclusions and RelevanceIn this quality improvement study of UCMyRx among Hispanic patients with T2D, a negative association was observed between UCMyRx exposure and HbA1cconcentration but not SBP. Pharmacist-led intervention may be a strategy for improving outcomes among Hispanic patients with T2D.
Tichowtungiia
Authors: Mu Da‐Shuai , Du Zong‐Jun 
Published: September 2023

Abstract

Ti.chow.tung.i'i.a. N.L. fem. n.
Tichowtungia,
type genus of the type order of the class; N.L. neut. pl. n.
Tichowtungiia
, the class of the order
Tichowtungiales
.

Verrucomicrobiota / Tichowtungiia

The class
Tichowtungiia
includes two genera represented by cultivated strains,
Tichowtungia
and
Pontiella,
as well as lineages of uncultivated bacteria. Cells of the cultivated genera are Gram‐stain‐negative, anaerobic, nonmotile, non‐spore‐forming, and coccus‐shaped. Cells grow poorly under low oxygen conditions. Phylogenetic analyses based on 16S rRNA genes and genomes indicate that
Tichowtungiia
branches within the radiation of the phylum
Kiritimatiellota
or
Verrucomicrobiota
.

DNA G + C content (mol%)
: 53–56.0.

Type order
:
Tichowtungiales
Mu et al. 2020
VP
.
Tichowtungiaceae
Authors: Mu Da‐Shuai , Du Zong‐Jun 
Published: September 2023

Abstract

Ti.chow.tung.i.a.ce'ae. N.L. fem. n.
Tichowtungia,
type genus of the family; L. fem. pl. n. suff. ‐
aceae,
ending to denote a family; N.L. fem. pl. n.
Tichowtungiaceae,
family of the genus
Tichowtungia
.

Verrucomicrobiota / Tichowtungiia / Tichowtungiales / Tichowtungiaceae

The species in
Tichowtungiaceae
are anaerobic, nonmotile, coccoid, Gram‐stain‐negative, and isolated from surface marine sediments. They are also non‐spore‐forming and arranged singularly or in pairs. Cells grow poorly under low oxygen conditions. Respiratory lipoquinones are not formed during anaerobic cultivation. The major cellular fatty acids are C
18:0
, iso‐C
12:0
, iso‐C
16:0
, and iso‐C
18:0
. The major polar lipids include diphosphatidylglycerol and phosphatidylglycerol. Phylogenetic analyses based on 16S rRNA genes and genome sequences indicate that
Tichowtungiaceae
branches within the radiation of the group
Kiritimatiellia
. The genus
Pontiella
can be considered to be within the family
Tichowtungiaceae
based on the positions of
Tichowtungia aerotolerans
S‐5007
T
and species of the genus
Pontiella
in the phylogenetic tree. However, some authors consider
Pontiella
a member of a separate family.

DNA G + C content (mol%)
: 53.1 (genome sequence).

Type genus
:
Tichowtungia
Mu et al. 2020
VP
.
Erythrobacter
Authors: Xu Lin , Zhang Yu , Xu Xue‐Wei 
Published: September 2023

Abstract

E.ry.thro.bac.ter. Gr. masc. adj.
erythros
, red; N.L. masc. n.
bacter
, rod; N.L. masc. n.
Erythrobacter
, red rod.

Pseudomonadota / Alphaproteobacteria / Sphingomonadales / Erythrobacteraceae / Erythrobacter

The genus
Erythrobacter
belonging to the family
Erythrobacteraceae
currently consists of fifteen species with validly published names:
Erythrobacter alti
,
Erb. ani
,
Erb. aurantius
,
Erb. colymbi
,
Erb. crassostreae
,
Erb. cryptus
,
Erb. dokdonensis
,
Erb. donghaensis
,
Erb. insulae
,
Erb. litoralis
,
Erb. longus
,
Erb. neustonensis
,
Erb. ramosus
,
Erb. rubeus
, and
Erb. sanguineus
. Historically,
Erb. longus
Och 101
T
was one of the first identified aerobic anoxygenic, photoheterotrophic bacteria. Members of
Erythrobacter
mainly inhabit various aquatic environments, including seawater, marine mats, freshwater, and hot spring, and could accumulate more biomass for a given amount of organic carbon in luminous than in the nonluminous environments, playing an essential role in the carbon cycle. Cells are Gram‐stain‐negative, and most of the members are motile by flagella. The main respiratory quinone is ubiquinone‐10. The major polar lipids are phosphatidylethanolamine (PE), phosphatidylglycerol (PG), and sphingoglycolipid (SGL). The predominant cellular fatty acids are C
18:1
ω7
c
and C
17:1
ω6
c
.

DNA G + C content (mol%)
: 57–67 (by genome sequence or HPLC).

Type species
:
Erythrobacter longus
Shiba and Simidu 1982
VP
.
Vallitalea
Authors: Fardeau Marie‐Laure , Postec Anne , Ollivier Bernard 
Published: September 2023

Abstract

Val.li.ta'le.a. L. gen. fem. n.
vallis,
a valley, vale; L. fem. N.
talea,
a rod; N.L. fem. n.
Vallitalea
, a rod isolated from a vale.

Firmicutes / Clostridia / Clostridiales / Vallitaleaceae / Vallitalea

The genus
Vallitalea
at the time of writing, comprises three species with validly published names,
Vallitalea guaymasensis
, which was isolated from sediments of Guaymas Basin,
Vallitalea okinawensis
, isolated from Okinawa Trough sediment, and
Vallitalea pronyensis
, obtained from a shallow submarine hydrothermal field in Prony Bay in the south of New Caledonia. The species of the genus are thermotolerant or mesophilic, moderately halophilic and strictly anaerobic, and they present a fermentative growth on some carbohydrates. Phylogenetic analyses using 16S rRNA gene sequences placed the three species as belonging to the phylum
Firmicutes
, class
Clostridia
, order
Clostridiales,
family
Vallitaleaceae
.

DNA G + C content (mol%)
: 31.2.

Type species
:
Vallitalea guaymasensis
Lakhal et al. 2013
VP
.
Hydrogenispora
Authors: Qiu Yan‐Ling 
Published: September 2023

AbstractHy.dro.ge.ni.spo'ra. N.L. neut. n.hydrogenum, hydrogen; from Gr. neut. n. hydôr, water; from Gr. ind. v. gennaô, to produce; Gr. fem. n.spora, a seed, and, in biology, a sporeHydrogenispora, a spore‐forming, hydrogen‐producing bacterium.Bacillota / unnamed Class / Order OPB54 / HydrogenisporaLong thin rods, nonmotile. Terminal spores with a bulging sporangium. Strictly anaerobic, chemoorganoheterotroph. Grows at 20–50°C (optimum of 37–45°C), pH 5.0–8.0 (optimum of pH 6.0–7.7), and 0–2.5% (w/v) NaCl. Fermentative growth with a range of carbohydrates, glycerol, fumarate, tryptone, and yeast extract. Major fermentation products from glucose include acetate, ethanol, and hydrogen. Represented by a single strain, namely the type strain LX‐BTof the type speciesHydrogenispora ethanolica, isolated from anaerobic sludge treating herbicide wastewater. The genome ofH. ethanolicaLX‐BTis 6.0 Mb in length, has a G + C content of 54.1 mol%, and contains 5,243 putative protein encoding and 71 RNA genes. Shares at most 90% 16S rRNA gene sequence similarity with other described species. Most closely affiliated with uncultured members of clade OPB54 in the Greengenes taxonomy, within the phylumBacillota.DNA G + C content (mol%): 54.1% (genome sequence).Type species:Hydrogenispora ethanolicaLiu et al. 2014VP.
Aquisalibacillus
Authors: Márquez María C. , Carrasco Inmaculada J. , Ventosa Antonio 
Published: September 2023

Abstract

A.qui.sa.li.ba.cil'lus. L. fem. n.
aqua
, water; L. masc. n. (gen.
salis
), salt; L. masc. n.
bacillus
, rod; N.L. masc. n.
Aquisalibacillus
, a rod living in salt water.

Bacillota / Bacilli / Bacillales / Bacillaceae / Aquisalibacillus

The genus
Aquisalibacillus
is classified within the family
Bacillaceae
and the order
Bacillales,
within the phylum
Bacillota
. The cells are long rod‐shaped, nonmotile, and stain Gram‐negative, but the cell wall is of the Gram‐positive type. KOH test is negative. Endospores are not observed. Strictly aerobic and moderately halophilic. Catalase positive and oxidase negative. Nitrate and nitrite are reduced. The cell wall contains an
l
‐Orn‐
d
‐Asp directly cross‐linked murein (type A4β) and the major menaquinone is MK‐7. Major cellular fatty acids are iso‐C
16:0
and iso‐C
15:0
. The only described species of the genus to date is
Aquisalibacillus elongatus
, which is represented by one strain isolated from water of a saline lake.

DNA G + C content (mol%)
: 37.4 (genome type strain of the species).

Type species
:
Aquisalibacillus elongatus
Márquez et al. 2008
VP
.
Polyhydroxylated Organic Molecular Additives for Durable Aqueous Zinc Battery
Authors: Liu Huan , Xin Zijun , Cao Bin , Xu Zhijing , Xu Bin , Zhu Qizhen , Yang Jin‐Lin , Zhang Bao , Fan Hong Jin 
Published: September 2023

AbstractThe large‐scale deployment of aqueous Zn‐ion batteries is hindered by Zn anode instability including surface corrosion, hydrogen gas evolution, and irregular Zn deposition. To tackle these challenges, a polyhydroxylated organic molecular additive, trehalose, is incorporated to refine the solvation structure and promote planar Zn deposition. Within solvation structure regions involving trehalose, the hydroxy groups participate in the reconstruction of hydrogen bond networks, which increases the overpotential for water decomposition reaction. Moreover, at the Zn metal–molecule interface, the chemisorption of trehalose onto the surface of the zinc anode enhances corrosion resistance and facilitates the deposition of zinc in a planar manner. The optimized electrolyte significantly improves Zn striping/plating reversibility and maintains stable potentials over 1600 h at 5 mA cm−2 with a cutoff capacity of 1 mA h cm−2 in symmetric cells. When combined with the MnO2 cathode, the assembled coin cell retains ≈89% of its capacity after 1000 cycles. This organic molecule additive, emphasizing the role of polyhydroxylated organic molecules in fine‐tuning solvation structures and anode/electrolyte interfaces, holds promise for enhancing various aqueous metal batteries.
A Multiscale, Dynamic Elucidation of Li Solubility in the Alloy and Metallic Plating Process
Authors: Li Shaowen , Chai Zhigang , Wang Zhaohui , Tai Cheuk‐Wai , Zhu Jiefang , Edström Kristina , Ma Yue 
Published: September 2023

AbstractLi‐containing alloys and metallic deposits offer substantial Li+ storage capacities as alternative anodes to commercial graphite. However, the thermodynamically in sequence, yet kinetically competitive mechanism between Li solubility in the solid solution and intermediate alloy‐induced Li deposition remains debated, particularly across the multiple scales. The elucidation of the mechanism is rather challenging due to the dynamic alloy evolution upon the non‐equilibrium, transient lithiation processes under coupled physical fields. Here, influential factors governing Li solubility in the Li‐Zn alloy are comprehensively investigated as a demonstrative model, spanning from the bulk electrolyte solution to the ion diffusion within the electrode. Through real‐time phase tracking and spatial distribution analysis of intermediate alloy/Li metallic species at varied temperatures, current densities and particle sizes, the driving force of Li solubility and metallic plating along the Li migration pathway are probed in‐depth. This study investigates the correlation between kinetics (pronounced concentration polarization, miscibility gap in lattice grains) and rate‐limiting interfacial charge transfer thermodynamics in dedicating the Li diffusion into the solid solution. Additionally, the lithiophilic alloy sites with the balanced diffusion barrier and Li adsorption energy are explored to favor the homogeneous metal plating, which provides new insights for the rational innovation of high‐capacity alloy/metallic anodes.
Polarization‐ and Gate‐Tunable Optoelectronic Reverse in 2D Semimetal/Semiconductor Photovoltaic Heterostructure
Authors: Wang Hanyu , Li Yan , Gao Peng , Wang Jina , Meng Xuefeng , Hu Yin , Yang Juehan , Huang Zihao , Gao Wei , Zheng Zhaoqiang , Wei Zhongming , Li Jingbo , Huo Nengjie 
Published: September 2023

AbstractPolarimetric photodetector can acquire higher resolution and more surface information of imaging targets in complex environments due to the identification of light polarization. To date, the existing technologies yet sustain the poor polarization sensitivity (<10), far from market application requirement. Here, the photovoltaic detectors with polarization‐ and gate‐tunable optoelectronic reverse phenomenon are developed based on semimetal 1T′‐MoTe2 and ambipolar WSe2. The device exhibits gate‐tunable reverse in rectifying and photovoltaic characters due to the directional inversion of energy band, yielding a wide range of current rectification ratio from 10−2 to 103 and a clear object imaging with 100 × 100 pixels. Acting as a polarimetric photodetector, the polarization ratio (PR) value can reach a steady state value of ≈30, which is compelling among the state‐of‐the‐art 2D‐based polarized detectors. The sign reversal of polarization‐sensitive photocurrent by varying the light polarization angles is also observed, that can enable the PR value with a potential to cover possible numbers (1→+∞/‐∞→−1). This work develops a photovoltaic detector with polarization‐ and gate‐tunable optoelectronic reverse phenomenon, making a significant progress in polarimetric imaging and multifunction integration applications.
Charge‐Selectively Permeable Self‐Healing Microcapsules
Authors: Li Chuen‐Ru , Lutz‐Bueno Viviane , Amstad Esther 
Published: September 2023

AbstractMicrocapsules possessing a selective permeability are well‐suited vessels for conducting cell studies or chemical reactions that require selective exchanges of reagents over a prolonged time. Most currently reported microcapsules are single‐use delivery carriers since cargo is only released in significant amounts if their shells are damaged or the release relies on passive diffusion. Stable capsules possessing a selective, rapidly interchangeable permeability, which enables their repeated loading and unloading with selected reagents remain to be shown. Here, capsules are introduced that are composed of thin, viscoelastic, charge‐selective shells made of surfactants that are functionalized with a chelator, 3‐hydroxy‐4‐pyridinonone and crosslinked with appropriate nm‐sized ion clusters, for example composed of Fe3+/Tris or Al3+/Tris ion clusters. The charge selectivity of the shell permeability can be conveniently tuned with the crosslinking ion clusters. It is demonstrated that these capsules can be repeatedly loaded and unloaded with well‐defined substances. This feature enables their application as re‐usable selectively permeable filters to remove certain pollutants from solutions. These capsules are envisaged to be well‐suited for waste water treatment and as picoliter‐sized reaction vessels to selectively conduct chemical reactions within capsule cores while continuously supplying new reagents.
Quasi‐Continuous Defect Levels in Broadband Gap: A New Strategy for High‐Temperature Long Persistent Luminescence Materials
Authors: Zhang Pan , Chen Xiang , Bai Yuxing , Zhao Xiaohui , Fu Xuewen , Wu Li , Wang Yuhua , Sun Tongqing , Kong Yongfa , Zhang Yi , Xu Jingjun 
Published: September 2023

AbstractLong persistent luminescence (LPL) materials widely employed in the fields of emergency lighting and anti‐counterfeiting are mostly used at room temperature. As temperatures rise, the performance of LPL materials deteriorates dramatically, which hinders their application in in vivo imaging, high‐temperature display, and information storage. Herein, a multifunctional material LiGa5O8:Tb3+ (LGT) with green high‐temperature LPL (HT‐LPL) and blue cathodoluminescence (CL) is reported. Its LPL performance is anomalously enhanced with increasing temperature, and the duration time is more than 8 h at 423 K. With combined temperature‐dependent decay curves and thermoluminescence analyses, the unique quasi‐continuous defect levels are found in the band gap. The high‐concentration carriers in deep traps are frozen at room temperature and activated only at high temperatures, accompanied by changes in energy transfer pathways. The excellent HT‐LPL makes LGT a light‐emitting component of next‐generation smart wearable devices, as well as high‐temperature warning equipment in deep well exploration at a depth of 4500 m. The intense anti‐degradation blue CL makes it suitable for field emission displays, while the manipulable emission property makes it suitable for high‐level anti‐counterfeiting. This study fills a gap in HT‐LPL materials and opens up a new gateway for the efficient design of HT‐LPL and other multifunctional materials.
YWHAG Deficiency Disrupts the EMT‐Associated Network to Induce Oxidative Cell Death and Prevent Metastasis
Authors: Lee Jeannie Xue Ting , Tan Wei Ren , Low Zun Siong , Lee Jia Qi , Chua Damien , Yeo Wisely Duan Chi , See Benedict , Vos Marcus Ivan Gerard , Yasuda Tomohiko , Nomura Sachiyo , Cheng Hong Sheng , Tan Nguan Soon 
Published: September 2023

AbstractMetastasis involves epithelial‐to‐mesenchymal transition (EMT), a process that is regulated by complex gene networks, where their deliberate disruption may yield a promising outcome. However, little is known about mechanisms that coordinate these metastasis‐associated networks. To address this gap, hub genes with broad engagement across various human cancers by analyzing the transcriptomes of different cancer cell types undergoing EMT are identified. The oncogenic signaling adaptor protein tyrosine 3‐monooxygenase/tryptophan 5‐monooxygenase activation protein gamma (YWHAG) is ranked top for its clinical relevance and impact. The cellular kinome and transcriptome data are surveyed to construct the regulome of YWHAG, revealing stress responses and metabolic processes during cancer EMT. It is demonstrated that a YWHAG‐dependent cytoprotective mechanism in the regulome is embedded in EMT‐associated networks to protect cancer cells from oxidative catastrophe through enhanced autophagy during EMT. YWHAG deficiency results in a rapid accumulation of reactive oxygen species (ROS), delayed EMT, and cell death. Tumor allografts show that metastasis potential and overall survival time are correlated with the YWHAG expression level of cancer cell lines. Metastasized tumors have higher expression of YWHAG and autophagy‐related genes than primary tumors. Silencing YWHAG diminishes primary tumor volumes, prevents metastasis, and prolongs the median survival period of the mice.
Genetically Engineered Cellular Nanovesicle as Targeted DNase I Delivery System for the Clearance of Neutrophil Extracellular Traps in Acute Lung Injury
Authors: Du Yang , Chen Yining , Li Fangyuan , Mao Zhengwei , Ding Yuan , Wang Weilin 
Published: September 2023

AbstractAcute lung injury (ALI)/acute respiratory distress syndrome (ARDS) are prevalent critical illnesses with a high mortality rate among patients in intensive care units. Neutrophil extracellular traps (NETs) are implicated in the pathogenesis of ALI/ARDS and represent a promising therapeutic target. However, the clinical application of deoxyribonuclease I (DNase I), the only drug currently available to clear NETs, is limited due to the lack of precise and efficient delivery strategies. Therefore, targeted delivery of DNase I to the inflamed lung remains a critical issue to be addressed. Herein, a novel biomimetic DNase I delivery system is developed (DCNV) that employs genetically and bioorthogonally engineered cellular nanovesicles for pulmonary NETs clearance. The CXC motif chemokine receptor 2 overexpressed cellular nanovesicles can mimic the inflammatory chemotaxis of neutrophils in ALI/ARDS, leading to enhanced lung accumulation. Furthermore, DNase I immobilized through bioorthogonal chemistry exhibits remarkable enzymatic activity in NETs degradation, thus restraining inflammation and safeguarding lung tissue in the lipopolysaccharide‐induced ALI murine model. Collectively, the findings present a groundbreaking proof‐of‐concept in the utilization of biomimetic cellular nanovesicles to deliver DNase I for treating ALI/ARDS. This innovative strategy may usher in a new era in the development of pharmacological interventions for various inflammation‐related diseases.
Significant Suppression of Dark Current in a Surface Acoustic Wave Assisted MoS2 Photodetector
Authors: Zhao Qianru , Yan Haoran , Wang Xudong , Chen Yan , Zhang Shukui , Wu Shuaiqin , Huang Xinning , Di Yunxiang , Xiong Ke , Zeng Jinhua , Jiao Hanxue , Lin Tie , He Hu , Ge Jun , Meng Xiangjian , Shen Hong , Chu Junhao , Wang Jianlu 
Published: September 2023

Abstract2D materials are considered as potential candidates for the next generation of optoelectronic materials. However, their optical absorption is typically weak due to thickness limitations, greatly restricting the photodetection capabilities of devices. To enhance the photoelectric gain of 2D materials or devices and improve detection sensitivity, various modulation methods such as strain, electric field, and magnetic field are commonly introduced. Among them, surface acoustic wave (SAW) represents a unique and effective modulation approach. In this study, photodetectors are fabricated based on few‐layer MoS2 on a SAW delay line on a LiTaO3 substrate. The interaction between SAW and MoS2 successfully manipulates the optoelectronic performance of the MoS2‐based devices. Under the influence of SAW, the dark current of the devices is significantly reduced by more than two orders of magnitude, while the photocurrent remains almost unchanged, resulting in excellent photoresponse performance. The devices provide a promising pathway for high‐performance optoelectronic applications and reveal a new possibility for acoustic devices in optoelectronics.