bluuebunny/crossref_metadata_2025_split huggingface dataset:
Molecular Epidemiology and Resistance Mechanisms of Tigecycline-Non-Susceptible A. baumannii Isolated from a Tertiary Care Hospital in Chongqing, China
Authors: Liao Jiajia , Huang Jinzhu , Xia Peiwen , Yang Bingxue , Dang Zijun , Luo Shengli , Tang Shiyu , Li Yuqiong , Han Qi , Xia Yun 
Published: December 2023

Abstract

Objectives
This study aimed to investigate the epidemiology and tigecycline resistance mechanisms of Tigecycline-Non-Susceptible A. baumannii (TNAB) isolates in a large tertiary care hospital in Chongqing, China.
Methods
From July 2019 to June 2022, 34 non-duplicate isolates of A. baumannii determined as tigecycline-non-susceptible by broth microdilution method were collected from a tertiary care hospital in Chongqing. The resistance-related genes were sequenced and the expression level of the resistance-nodulation-cell division (RND) efflux pumps was investigated. The activity of the RND efflux pumps was examined by adding efflux pump inhibitors (EPIs). The molecular epidemiology was analyzed by multi-locus sequence typing (MLST) and goeBURST software.
Results
In this study, the TNAB strains were primarily obtained from ICU and had high resistance rates to commonly used antibiotics. Tigecycline resistance-associated genes adeR, adeS, adeL, adeN, rrf, and rpsJ were detected in most strains. All TNAB strains exhibited 240 nucleotide deletion mutation in the trm gene. The expression level of the RND efflux pumps in TNAB strains was higher than the reference strain ATCC19606. 58.82% of strains had a decrease in the tigecycline minimum inhibitory concentration (MIC) after the addition of carbonyl cyanide 3-chlorophenylhydrazone (CCCP). A total of 8 ST types were identified, including ST195 (35.29%), ST208 (17.65%), and ST369 (14.71%). EBURST analysis found that 8 of the ST types belonged to the Clonal Complex 92.
Conclusion
The TNAB strains in our hospital have a high degree of affinity and antibiotic resistance. Regular surveillance should be conducted to prevent outbreaks of TNAB epidemics.
Exploring High-Order Features in Multimodal Recommendations using Graph Convolutional Neural Networks
Authors: Reyes Emiliano , Mercer Greta , Nieves Valeria 
Published: December 2023

Abstract
Following the introduction of graph neural networks, researchers have discovered the potential of using these networks to extract interconnections between users and items, which are often challenging for traditional recommendation algorithms to capture. The use of graph neural networks in constructing recommendation algorithms has gradually become a current trend in recommendation algorithm research. Currently, most recommendation algorithms based on graph neural networks extract user and item features using ID information, neglecting the implicit user and item features present in other data such as textual reviews. Alternatively, some algorithms incorporate auxiliary information, but this often complicates network training. To address this, our paper proposes a recommendation algorithm based on a graph neural network that integrates traditional deep learning, combining different user and item features. We introduce an attention mechanism to capture higher-order characteristics between users and items as part of the user and item feature representation. Simultaneously, we employ a traditional deep learning network to extract user and item features from textual data. The final user and item feature representation is obtained by merging these two feature representations, leading to improved recommendations. Experimental results demonstrate that this method effectively integrates high-order features and general characteristics of users and items, enhancing the representation of user and item features and consequently improving recommendation performance.
Assessment of the quality of groundwater body of Neelangarai and Triplicane areas in Chennai, Tamil Nadu in the post-inundation circumstances
Authors: Rajendran A. , Mansiya C. , Shanmuganathan M. 
Published: December 2023

Abstract

Although flooding hit the entire part of Chennai, Tamil Nadu some 3 years ago, the quality of water is still found to be worse because of major inundation in these areas. The current inspection deals with the physico-chemical analysis of the groundwater samples collected from 10 locations in Neelangarai and Triplicane areas in Chennai, Tamil Nadu, and assessed using the Heber Water Quality Index (HWQI) in the post-tsunami circumstances. The factors examined were pH, fecal coliform, total dissolved solids (TDS), dissolved oxygen (DO), temperature, biochemical oxygen demand (BOD), and turbidity. In addition to these parameters, pointers like electrical conductivity and salinity were also taken into consideration. The overall HWQI outcomes for all the trials in the Neelangarai area were determined between 65.02 and 72.25 and the Triplicane area was 66.64–70.71, which suggests that all the samples are medium to good in quality and could be used for human consumption.
Contribution of Posterior Corneal Astigmatism to Total Corneal Astigmatism among Saudi Population
Authors: Fahmy Rania , Alandas Sarah 
Published: December 2023

Background:
Astigmatism is an error of refraction in which incident parallel rays cannot be focused on a single point. It could be corneal astigmatism (CA), lenticular astigmatism (LA), or both. Regarding CA, it is due to the difference in the corneal curvature in the different meridians of both the anterior and posterior surfaces. The anterior and posterior corneal surfaces contribute to total corneal astigmatism (TCA). Newer technologies, such as slit-scanning technology, Scheimpflug devices, and optical coherence tomography, are now used in the clinical setting for measuring the posterior corneal surface. However, it has been shown that relying only on the anterior corneal surface measurement and neglecting the relationship between the anterior and posterior corneal surfaces can lead to unacceptable intraocular lens (IOL), power calculation results after corneal refractive surgery, and errors during the calculation of toric IOLs.

Objectives:
This study aimed to determine the percentage of contribution of the magnitude of posterior corneal astigmatism (PCA) to total corneal astigmatism (TCA) and to investigate the correlation between anterior corneal astigmatism (ACA), PCA, and TCA.

Methods:
A prospective cross-sectional study including 55 subjects aged 18 – 31 years old and divided into 3 groups based on spherical equivalent (SE), Emmetropia, Hyperopia, and Myopia were included. All subjects underwent full ophthalmological examinations and corneal topography. ACA and PCA were evaluated. TCA was computed by the addition of the ACA and PCA using vector analysis. The percentage of contribution of the PCA to the magnitude of the TCA and the correlation between ACA, PCA, and TCA were calculated.

Results:
All subjects had anterior corneal with the rule (WTR) astigmatism. The contribution of PCA to TCA for all subjects in 3 groups (Emmetropia, Hyperopia, and Myopia) was 35%, 37%, and 37%, respectively, with P > 0.05, which was not statistically significant. There was a correlation between ACA, PCA, and TCA in all study groups.

Conclusion:
TCA is composed of both corneal surfaces, and PCA impacts the outcomes of refractive surgeries for correcting astigmatism and in toric intraocular lens (IOL) calculation when just based on the data of the anterior corneal surface.
Unraveling the Link between Self-efficacy and self-management in Breast Cancer Patients during the COVID-19 Pandemic: A Cross-sectional Study
Authors: Suryani Dwi , Nuraini Tuti , Gayatri Dewi , Milanti Ariesta 
Published: December 2023

Background:
The COVID-19 pandemic necessitates that cancer patients take on a more active role in self-managing their illness and adjusting to the altered healthcare resources. To perform self-management behaviors, patients may need an adequate level of self-efficacy. However, little is known about breast cancer patients’ self-efficacy and self-management in pandemic times.

Aim:
This study aimed to assess the self-efficacy and self-management of breast cancer patients undergoing therapy during the COVID-19 pandemic and identify their associations.

Methods:
A descriptive-analytical, cross-sectional design was used. One hundred and eight breast cancer patients undergoing treatment were recruited from the National Cancer Center in Indonesia. Participants completed questionnaires that consisted of the Cancer Behavior Inventory, the Depression Anxiety Stress Scale, the Enrichd Social Support Instrument, and the Self-Management Assessment Scale. Data were analyzed using multiple regression.

Results:
The study found that 45.4% and 42.6% of breast cancer patients under treatment had a low level of self-efficacy and self-management, respectively. Self-efficacy is positively associated with self-management in breast cancer patients (p=0.001) after controlling for various factors, including cancer stage, psychological factors, and social support. The factor most related to self-management is self-efficacy, as measured by the odds ratio (OR), which was 16.713 (95% CI: 4.424-63.137), while the ORs of social support and stage were 4.968 (95% CI: 1.785-13.831) and 0.190 (95% CI: 0.044-0.820), respectively.

Conclusion:
It can be concluded that self-efficacy is strongly and positively associated with self-management in breast cancer patients undergoing treatment. Therefore, nursing interventions focusing on enhancing patients’ self-efficacy are needed.
Analyzing Uttarakhand's COVID-19 Outbreak: Demographic Insights and
Strategies for Future Pandemic Prevention
Authors: Joshi Gaurav , Pande Akshara , Gupta Omdeep , Nautiyal Anoop , Jasola Sanjay , Gahtori Prashant 
Published: December 2023

Background::
The Indian state of Uttarakhand, also known as "Dev Bhoomi" or the
Abode of Gods, is snuggled in the lap of the Himalayas. It is endowed with an abundant natural hilly
environment and occupies more people in total than Israel, Switzerland, Hong Kong, etc. In this report,
we look closely at the impact of COVID-19 on both high land/ hilly and low land/ plain bhabar
zones across the state.

Methods::
The data was retrieved from the Uttarakhand Government Covid-19 health bulletin for 12
months using the Python command line. The data analysis covers percentage positivity/COVID-19
positivity rate, recovery, deceased and doubling rate, along with a detailed statistical analysis.

Results::
In the first wave, low-land- inhabitants residing in 4 districts, Dehradun, Haridwar, U. S.
Nagar and Nainital, were found more vulnerable, with a peak positive case during the 21st – 26th
week. On the other hand, the districts with exclusive hilly terrains, including Chamoli, Pauri
Garhwal, and Rudraprayag, were found to be the least susceptible and reported a high number of
positive cases between the 30th and 31st week. The highest recovery rate was found to be in the hilly
district of Rudraprayag. The multiple regression with confirmed cases was explained in relation to
deceased, recovered, other, and tested variables (R2 adj= 0.99). The analysis also revealed a very
high doubling rate from the last week of May to the first week of Jun 2020.

Conclusion::
The reduced number of COVID-19 cases in high-altitude hilly districts may be associated
with factors such as enhanced ventilation, improved arterial oxygen transport, and increased
tissue oxygenation. The findings from this study offer insights that can contribute to future pandemic
prevention efforts. Summarising the current study, we have suggested 5-point solutions for preventing
the next pandemic. It's important to note that while this study suggests a potential link between
these factors and lower COVID-19 cases, further research is needed to establish a conclusive connection.
Methodical and Immunological Insights of Prime COVID-19 Vaccines
Authors: Evangeline Wilson Pearl , Divyasri Sakthivelnathan , Akshaya Chandrasekaran , Sruthi Sekar , Selvaraj Barathi , Kirubakaran Rangasamy , ArulJothi Kandasamy Nagarajan 
Published: December 2023

Abstract::
Vaccines' discovery, manufacturing, and distribution have been on a historic uptick in
response to this worldwide COVID-19 pandemic. A handful of vaccines have been approved on an
emergency basis after passing minimal clinical trials. There are voids in the existing body of research
and the published body of work on phase II and III clinical trial outcomes, efficacy, and recently
developed side effects of the approved COVID-19 vaccines. Furthermore, the immunological and
methodological insights of successful vaccinations are still unpopular and are not publicly reported.
We have attempted to review some major classes of COVID-19 vaccines, namely inactivated viral
particle vaccine (BBV152 - Covaxin), mRNA vaccines (BNT162b2 - Pfizer and mRNA-1273-
Moderna), viral vector vaccines (Gam-COVID-Vac-Sputnik and ChAdOx1-S-Astrazeneca) and protein
subunit vaccine (NVX-CoV2373-Novavax) and discuss their methodological and immunological
formulations. This review intends to address the existing literature's gaps and limitations and the
vaccine’s safety, efficiency, and effectiveness profiles. This report, by accumulating and comparing
the existing publicly available literature and datasheets of the vaccines, concludes that the efficacy of
the vaccinations has been found to be 81% for BBV152 (COVAXIN), 94.5% for BNT162b2 (Pfizer),
94.5% for mRNA-1273 (Moderna), 91.6% for Gam-COVID-Vac (Sputnik V), 62–90% for
ChAdOx1-S (AstraZeneca), and 96.4% for NVX-CoV2373 (Novavax), demonstrating their efficacy
in lowering the severity and frequency of SARS-CoV-2 infection. We conclude that while the commercially
approved vaccines have a few limitations regarding clinical trials and side effects, they
provide immunity with efficacy ranging from 81% to 96.4% against COVID-19.
Comparison of Women's Sexual Activity Before and After being Infected
with COVID-19
Authors: Keshavarz Zohreh , Shariatifar Naeimeh , Nasiri Maliheh , Kiani Zahra 
Published: December 2023

Introduction:
Sexual activity is one of the main aspects of sexual health, which has been
less considered during the COVID-19 pandemic. This study was conducted to compare the sexual
activity of women before and after being infected with COVID-19.

Methods::
This descriptive cross-sectional study included 110 women diagnosed with COVID-19.
The data were collected before and after one month of quarantine in a 24-hour clinic and a 24-hour
referral center for COVID-19 in Pakdasht city, Tehran, Iran. The study was conducted from the
spring of 2020 to the winter of 2022. Demographic characteristics questionnaire and FSFI
questionnaire were used as data collection tools. Statistical analysis was performed using SPSS
version 22.

Results::
Based on the results, there was a significant difference in the total scores of the women's
sexual activity before and after the infection (P˂0.0001). The scores showed a decrease following the
infection, and the greater the severity of the infection, the more was the decrease. A significant
difference was observed in all domains of the women's sexual activity before and after the infection,
indicating that the pre-infection scores were higher (P˂0.05).

Conclusion::
Given the decreased scores of women's sexual activity after being infected with the
coronavirus, more attention should be paid to this area. Women and their spouses should be educated
during such pandemics and appropriate planning should be done before similar incidences to avoid
long-term negative effects.
PENGARUH LITERASI KEUANGAN, GAYA HIDUP, DAN PENGENDALIAN DIRI TERHADAP PERILAKU KONSUMTIF MAHASISWA FAKULTAS EKONOMI UNIVERSITAS PENDIDIKAN GANESHA
Authors: Putra I Gusti Lanang Prayura , Sinarwati Ni Kadek 
Published: December 2023

Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh literasi keuangan, gaya hidup, dan pengendalian diri terhadap perilaku konsumtif mahasiswa. Penelitian ini merupakan penelitian kuantitatif dengan menggunakan sumber data primer yang berasal dari pengisian kuesioner oleh responden. Kuesioner dalam penelitian ini menggunakan skala likert 1-5. Populasi dalam penelitian ini adalah mahasiswa Fakultas Ekonomi Universitas Pendidikan Ganesha yang aktif pada semester genap 2021/2022. Jumlah sampel dihitung menggunakan rumus Slovin dan pengambilan sampel menggunakan teknik simple random sampling. Analisis data menggunakan regresi linear berganda dengan aplikasi IBM SPSS versi 25. Hasil penelitian menunjukkan secara parsial literasi keuangan dan pengendalian diri berpengaruh negatif dan signifikan terhadap perilaku konsumtif mahasiswa Fakultas Ekonomi Universitas Pendidikan Ganesha, sedangkan gaya hidup berpengaruh positif dan signifikan terhadap perilaku konsumtif mahasiswa Fakultas Ekonomi Universitas Pendidikan Ganesha.
Pengaruh Perkembangan Aplikasi Investasi, Risiko Investasi dan Pengetahuan Investasi terhadap Minat Investasi Pasar Modal pada Generasi Milenial dan Generasi Z Provinsi Bali di Era Pandemi
Authors: Ardani Andri Kerti , Sulindawati Ni Luh Gede Erni 
Published: December 2023

Abstract
The recent development of investment applications has encouraged millennials and generation z to start investing. The amount of free time and the declining prices of instruments on the capital market during the pandemic are several other factors that raise their interest in investing. This research was conducted in the province of Bali by grouping respondents from the millennial generation and generation z. In this study using quantitative methods with the data used is primary data sourced from the results of questionnaires that have been distributed to 100 respondents with google form. The purpose of this study was to determine the effect of the development of investment applications, investment risk and investment knowledge on the millennial generation and gen Z of Bali province in the pandemic era. The results of the study indicate that application development, investment risk and investment knowledge have a positive and significant impact on capital market investment interest in millennial and generation z generations in Bali.

Keywords : investment application development, investmentrisk, investment knowledge, investment interest.
Pengaruh Premi, Klaim, Dan Profitabilitas Terhadap Pertumbuhan Aset Pada Perusahaan Asuransi MAG Periode 2018-2021
Authors: Arta Dewi Dian , Yuniarta Gede Adi 
Published: December 2023

Penelitian ini bertujuan untuk mengetahui bagaimana dan seberapa besar pengaruh premi, klaim, dan profitabilitas terhadap pertumbuhan asset pada perusahaan asuransi MAG. Variabel yang diteliti meliputi premi, klaim, dan profitabilitas sebagai variabel bebas dan pertumbuhan asset sebagai variabel terikat. Penelitian ini termasuk jenis penelitian deskriptif kuantitatif. Populasi dalam penelitian ini adalah perusahaan asuransi MAG dari tahun 2018-2021, sedangkan sampelnya adalah 14 kantor cabang di Indonesia tahun 2018-2021. Teknik analisis data yang digunakan dalam penelitian adalah analisis regresi linier berganda. Berdasarkan hasil pengujian statistik dan analisis pembahasan, baik secara simultan maupun parsial premi tidak berpengaruh terhadap pertumbuhan aset. Klaim, dan profitabilitas berpengaruh signifikan terhadap pertumbuhan aset.
Kata kunci: Premi, Klaim, Profitabilitas, Dan Pertumbuhan Aset
Penerapan Akuntansi Biaya Lingkungan Pada PT. Jaya Baru Lestari
Authors: Ni Made Meli Darma Yanthi  , Ni Wayan Yulianita Dewi  
Published: December 2023

Penelitian ini bertujuan untuk mengetahui penerapan akuntansi biaya lingkungan pada PT. Jaya Baru Lestari. Penelitian ini menggunakan jenis penelitian kualitatif. Metode pengumpulan data yang dig unakan dalam penelitian ini yaitu wawancara, observasi, dan dokumentasi. Teknik analisis data yang digunakan yaitu teknik analisis kualitatif model Miles dan Huberman. Hasil penelitian ini menjelaskan bahwa PT. Jaya Baru Lestari sudah melakukan tahapan penerapan akuntansi untuk biaya pengelolaan limbah, namun belum sesuai dengan PSAK Nomor 1 paragraf 14 Tahun 2015. Hal ini diketahui berdasarkan dari pengakuan dan pengukuran, dalam pengukuran perusahaan telah mengakui biaya pengelolaan limbah serta dalam pengukuran biaya lingkungan (dalam hal pengelolaan limbah) yang dilakukan oleh PT. Jaya Baru Lestari menggunakan satuan rupiah, akan tetapi dalam mengidentifikasi, mengungkapkan, serta menyajikan biaya pengelolaan limbah perusahaan belum melakukannya secara benar. Perusahaan masih menggabungkan biaya lingkungan ke dalam biaya produksi, seharusnya perusahaan membuat akun biaya lingkungan secara khusus dalam laporan laba rugi.
Trends and Challenges of Text-to-Image Generation: Sustainability Perspective
Authors: Ivezić Dora , Babac Marina Bagić 
Published: December 2023

Abstract
Text-to-image generation is a rapidly growing field that aims to generate images from textual descriptions. This paper provides a comprehensive overview of the latest trends and developments, highlighting their importance and relevance in various domains, such as art, photography, marketing, and learning. The paper describes and compares various text-to-image models and discusses the challenges and limitations of this field. The findings of this paper demonstrate that recent advancements in deep learning and computer vision have led to significant progress in text-to-image models, enabling them to generate high-quality images from textual descriptions. However, challenges such as ensuring the legality and ethical implications of the final products generated by these models need to be addressed. This paper provides insights into these challenges and suggests future directions for this field. In addition, this study emphasises the need for a sustainability-oriented approach in the text-to-image domain. As text-to-image models advance, it is crucial to conscientiously assess their impact on ecological, cultural, and societal dimensions. Prioritising ethical model use while being mindful of their carbon footprint and potential effects on human creativity becomes crucial for sustainable progress.
Gambaran pengetahuan, sikap, dan perilaku mencuci tangan memakai sabun pada mahasiswa kedokteran
Authors: Nugroho Dodo , Tirtasari Silviana 
Published: December 2023

Perilaku hidup bersih dan sehat (PHBS) dapat diterapkan dalam kehidupan sehari-hari baik dirumah, kampus maupun fasilitas umum. Perilaku hidup bersih dan sehat dapat dilakukan dalam setiap sisi kehidupan kapan saja dan dimana saja. Cuci tangan (handwashing) merupakan bagian dari salah satu perilaku hidup bersih dan sehat (PHBS) yang berguna untuk sanitasi tangan dengan membersihkan tangan dan jari jemari menggunakan air untuk menjadi bersih dan memutus rantai kuman. Studi ini ialah studi deskriptif dengan desain cross-sectional yang dilakukan pada mahasiswa Kedokteran Universitas Tarumanagara. Studi ini ditujukan untuk mengetahui gambaran tingkat pengetahuan, sikap, dan perilaku mencuci tangan pakai sabun. Partisipan studi berjumlah 103 partisipan. Data gambaran pengetahuan, sikap, dan perilaku yang diperoleh melalui kuisioner. Hasil studi didapatkan tingkat pengetahuan yang baik tentang cuci tangan pakai sabun sebanyak 60 (52,2%) partisipan, sikap positif terhadap tentang cuci tangan pakai sabun 112 partisipan (97,4%), dan berperilaku baik terhadap tentang cuci tangan pakai sabun hanya 20 partisipan (17,4%). Temuan ini menunjukkan bahwa pengetahuan yang baik dan sikap yang positif belum tentu mencerminkan perilaku yang baik dalam mencuci tangan pakai sabun pada mahasiswa Fakultas Kedokteran Universitas Tarumanagara.