bluuebunny/crossref_metadata_2025_split huggingface dataset:
Concentración de radionucleidos en algunos hongos basidiomicetos silvestres del Monumento Natural Loma Isabel de Torres
Authors: Binet-Álvarez Andri , Santos-Mella Francisco , Sánchez Vásquez Junior , Tavárez Martínez Vinicio Argenio , Fermín Fernández Manuel Enrique , Paino Perdomo Omar 
Published: December 2023

Los hongos juegan un papel importante en la movilidad y acumulación de sustrato, y pueden utilizarse para determinar los niveles de concentración de radionucleidos en el medio ambiente. Este estudio muestra la diversidad de radionucleidos presentes en el suelo del Monumento Natural Loma Isabel de Torres en algunos hongos basidiomicetos silvestres. Los radionúclidos se determinaron con un espectrómetro gamma de Germanio Hiper Puro GX5019 con analizador de espectro digital DSA 1000, utilizando el software Genie 2000. Los organismos analizados fueron Ramaria sp., Sparassis spathulata, Russula sp. y Boletus sp. La actividad específica se obtuvo para cada uno de los basidiocarpos y su respectiva muestra de sustrato circundante. Además, se calculó el factor de bioacumulación. En los hongos se detectaron 137Cs y 40K, mientras que no se encontraron 232Th, 226Ra ni 210Pb. Las muestras de suelo tomadas a mayor altura presentaron una mayor concentración de 226Ra. Con base en estos hallazgos, se recomienda continuar el trabajo en esta línea de investigación.
Impacto potencial de un acuerdo de cielos abiertos entre los EE. UU. y la República Dominicana
Authors: Vásquez Harold , Vidal José 
Published: December 2023

En el último año, la República Dominicana ha mostrado interés en firmar acuerdos de cielos abiertos con sus principales socios comerciales y turísticos. En este estudio, utilizando técnicas de datos de panel, estimamos el impacto de los acuerdos de cielos abiertos (ACA) en el volumen de tráfico aéreo entre los países de América Latina y los Estados Unidos, con el objetivo de comprender el impacto de estos acuerdos en la región. A partir de estas estimaciones, asumiendo que un ACA entre la República Dominicana y los Estados Unidos tenga un impacto similar al promedio regional, calculamos que el ACA podría aumentar el número de vuelos procedentes de los Estados Unidos desde 28,934 (cifra del año 2022) hasta aproximadamente 35,900 vuelos anuales, al igual que incrementar la llegada de pasajeros no residentes en unos 600,000 visitantes adicionales. En general, un ACA entre Estados Unidos y la República Dominicana incrementaría los ingresos por turismo desde los Estados Unidos alrededor de un 24 %, equivalente a unos 746.2 millones de dólares adicionales.
THE CULINARY POTENTIAL OF THE ARCHIPELAGO AS TOURISM DEVELOPMENT WITH A HISTORICAL REVIEW OF CASE STUDIES YOGYAKARTA AND BANYUWANGI
Authors: Soetopo Dhalia , Wulandari Nuryuana Dwi 
Published: December 2023

The development of the world of tourism after the Covid-19 pandemic provides opportunities for the development of tourism products. This study aims to determine the potential of traditional food in Yogyakarta as tourism development; To find out the potential of traditional food in Banyuwangi. This study uses a descriptive qualitative research method with data collection techniques in the form of interviews with sources, documentation, and supported by literature. The results of this study indicate that 1) Yogyakarta as a tourist city has many menus that can be used to attract tourists including gudeg, bakpia, ingkung, tiwul and Gatot, stir fry mercon, 2) traditional food menus that can be used to attract tourists including botok wasp, uceng-uceng, lanun, pepes olin, and kelemben. These traditional food menus are inseparable from the history of the first time these menus existed and were served. Based on the discussion that has been conveyed by the researchers, it can be concluded that traditional food influences tourists to visit an area, it is necessary to have a good relationship between the government, the community and tourists. If regional tourism is developed, the economy of the community around the tourist object will also feel a positive impact.
Dysfunctional family as a determinant of mercenary and forcible crimes of minors and young people
Authors: Kulik L.M. 
Published: December 2023

The article is devoted to the problems of criminological determination of mercenary and forcible crimes of minors and youth. The author defines dysfunctional family as one of the main determinants of mercenary and forcible crimes among minors and youth.
The article characterizes the influence of adversity in the family, defects of family upbringing on the formation of a young personality.
The author analyzes modern criminological concepts regarding family problems as determinants of juvenile and youth crime and notes that the aggravation of problems of family dysfunction against the general background of poverty and constant need, moral and social degradation that occurs in families, lead to extremely negative consequences.
It is a well-known fact that the intensity of crime is particularly high among minors and young people from disadvantaged families. Basically, drunkenness, drug addiction, and prostitution thrive in these families, there are no moral foundations, elementary culture. All this affects the formation of the character of the individual, because the influence of the family, upbringing is of decisive importance.
Negative socio-economic and political processes significantly weakened the importance of the family institution as a social institution that protected children and youth. The majority of juvenile criminals were brought up in dysfunctional, single­parent families with a critical financial situation, and were witnesses of scandals and fights.
Parents who lead an immoral lifestyle, are indifferent to the interests of the child, are unable to provide the proper conditions for the normal psychophysical development of the child, and the deterioration of the financial situation of families leads to the inaccessibility due to the increase in the prices of using the benefits of civilization and, combined with discomfort in the family, provokes minors spending more and more time outside.
The article provides a criminological description of the modern aspects of family dysfunction, which are associated with military actions and the temporary occupation of large territories, and also complements the classification of dysfunctional families, which is developed today by criminological science.
Non-compete agreements: actual problems of Ukrainian legislation
Authors: Ivaniura I. , Shevchenko D. , Zinchenko A. 
Published: December 2023

This article is devoted to the study of non­competition agreements (prohibition of competition) in Ukrainian legislation, their legal regulation. This mechanism is used to regulate the relationship between the employer and the employee in order to protect the legitimate interests of the employer. The most common scientific approaches used to determine the legal nature of non-competition agreements in the legal doctrine, and they are evaluated. The authors established that, in essence, non-competition agreements are obligations with a negative content, despite that they are not provided for by the Civil Code of Ukraine.
The article analyzes the legislation of Western countries concerning non-compete agreements, in particular France, Italy and the USA. The authors came to the conclusion that the provisions of the legislation of these countries are similar and establish the following requirements for contracts of this type: 1) to be in writing; 2) remuneration for the employee; 3) the duration of the obligation which is mainly in several years, the applicable territory and activities that are prohibited to perform. If one of the conditions is missing, then this is the basis for declaring an agreement invalid.
Ukrainian legislation was analyzed, in particular the Law of Ukraine "On stimulating the Development of Digital Economy in Ukraine”, which provides for the concluding of non-compete agreements of Diya City residents. The authors came to the conclusion that, in general, Ukrainian labor legislation and civil legislation do not allow the conclusion of non­competition agreements, expect those provided for by the specified Law, because they violate human rights to work and entrepreneurial activity, and there are no laws that can limit these rights.
An analysis of judicial practice is carried out, which is diametrically opposite, to some extent contradictory, because it is at the stage of formation. Since non-competition agreements exist in practice, the authors come to the conclusion that this topic is subject to further research.
Review of default judgment in civil proceedings
Authors: Fennych V. 
Published: December 2023

The article is devoted to the analysis of the procedure for review of a decision in absentia in a civil proceeding by a court of first instance and its procedural consequences.
It is noted that there is a special and general procedure for reviewing a decision in absentia in a civil process, where submitting an application for review of a decision in absentia to the court that passed it is considered as a special procedure for reviewing it. It is indicated that this procedure can be considered in the context of self-control of the court of first instance in civil proceedings.
The subjects of submitting an application for review of a decision in absentia, its form, content, terms and procedure of submission are analyzed. Attention is drawn to the attachments to the application for review of the decision in absentia. It is indicated that the defendant has the right to submit such an application even if the decision in absentia is passed in his favor.
An application for review of a decision in absentia may not be considered by the court and returned to the person if he has not registered an electronic office in the Unified Judicial Information and Telecommunication System. Until such a person registers an electronic account, he cannot demand the cancellation of a decision in absentia. The specified procedural consequences also occur if the interests of a person who has not registered an electronic account are represented by a lawyer who has a registered electronic account. This manifests a limitation in a person's ability to protect his rights, freedoms and interests in court.
The procedure for considering an application for review of a decision in absentia is analyzed, and the grounds for court rulings on the satisfaction of such an application and cancellation of the decision in absentia or leaving the application unsatisfied are investigated. It is noted that the satisfaction of the application for review of the decision in absentia does not yet mean the adoption of the court decision automatically in favor of the defendant, since the consideration of the case starts from the beginning on general principles. The court will schedule a new court session to consider the merits of the case, informing all interested participants in the process.
Attention is drawn to the peculiarity of the defendant's exercise of the right to appeal against a decision in absentia or a repeated decision in absentia, and it is also indicated under which conditions this is possible. It is noted what to do if an application for annulment of a decision in absentia by the defendant and an appeal by the plaintiff was filed at the same time.
Economic and Legal Principles of Cybersecurity as a Prerequisite for the Introduction of Special Economic Regimes
Authors: Sieriebriak S.V. 
Published: December 2023

The article conducts a scientific and practical study of the economic and legal aspects of the State policy in the field of cybercrime and its impact on business development in a particular region, country, etc. It is determined that the massive spread of cybercrime, the lack of effective mechanisms for combating economic crimes, and the leveling of conceptual approaches to creating an effective mechanism for legal support of the business environment development have a negative impact on the investment environment in particular and on ensuring sustainable development of the State as a whole. The author analyzes the regulatory and legal documents which form the legal basis of the mechanism for combating cybercrime, both at the international and national levels. The author identifies the weaknesses of the national system of legal regulation of cybersecurity. The author points out the sufficiency and fragmented nature of legislative support for cybersecurity and counteraction to the growth of economic crimes.
It is established that the significant vulnerability of Ukraine's information sphere is due to the excessive use of foreign-made material and technical means. It is emphasized that the international scale of the fight against cybercrime requires clarification and harmonization of national legislation in order to be able to cooperate with law enforcement agencies abroad. The article focuses on the low efficiency of Ukraine's current cybersecurity system and the urgent need to improve and optimize it. Achieving this will not only solve the problem of information space security, but also ensure the continuity and sustainability of Ukraine's economic development.
It is determined that one of the priority areas of work in the field of creating optimal conditions for business is the fight against computer crimes in the economic sphere. Among the main tasks in this area of activity is to counteract the legalization of shadow income. The analysis of money laundering schemes shows that organized crime is very interested in using the capabilities of electronic payment systems which allow for instant money transfers with almost complete anonymity of counterparties.
Encuadres en la cobertura sobre IA en Argentina
Authors: Azzara Esteban 
Published: December 2023

Este trabajo se propone dar cuenta del modo en que los medios digitales más populares de Argentina presentaron, durante la primera mitad de 2023, el tema "Inteligencia Artificial".
Con ese propósito construimos un corpus de datos integrado por cien noticias de los cinco medios digitales más populares de Argentina (Infobae, TN online, Clarín online, La Nación online, A24 online) que hayan sido consideradas en cada uno de los medios como “más relevante” en junio de 2023.
El análisis de este corpus nos permitió identificar que los principales medios digitales de Argentina, presentaron la información sobre Inteligencia Artificial a partir de cuatro encuadres: Impacto sobre actividades laborales y/o productivas, Elaboración y consumo de contenidos para redes sociales y ocio, Consecuencias a futuro, Regulaciones y límites.
En la sección de resultados de este trabajo ofrecemos dos tablas en las que presentamos el total de las noticias distribuidas según sus tópicos y temas y la información de la frecuencia con que cada uno de los encuadres fue identificado en el corpus de noticias estudiado, señalando su valoración positiva o negativa.
Inteligencia Artificial Generativa y la Formación de Formadores
Authors: Rosignoli Silvina 
Published: December 2023

Este artículo representa un avance inicial de una tesis de maestría en Tecnología Educativa en curso, centrada en la formación de formadores para la integración de la Inteligencia Artificial Generativa (IAG) en la enseñanza universitaria. Se aborda el desarrollo de un marco teórico en construcción y se da cuenta de las indagaciones preliminares a docentes universitarios y expertos en el campo, resaltando los desafíos didácticos que la integración de estas tecnologías presentan para la enseñanza. Se subraya la necesidad de una reflexión crítica y propositiva sobre la inclusión de estas tecnologías en la enseñanza universitaria. Se dejan abiertos algunos interrogantes.
Clinical and prognostic implications of heart failure hospitalization in patients with advanced heart failure
Authors: Pagnesi Matteo , Sammartino Antonio Maria , Chiarito Mauro , Stolfo Davide , Baldetti Luca , Adamo Marianna , Maggi Giuseppe , Inciardi Riccardo Maria , Tomasoni Daniela , Loiacono Ferdinando , Maccallini Marta , Villaschi Alessandro , Gasparini Gaia , Montella Marco , Contessi Stefano , Cocianni Daniele , Perotto Maria , Barone Giuseppe , Merlo Marco , Cappelletti Alberto Maria , Sinagra Gianfranco , Pini Daniela , Metra Marco , Lombardi Carlo Mario 
Published: December 2023

Background
Hospitalization is associated with poor outcomes in patients with heart failure, but its prognostic role in advanced heart failure is still unsettled. We evaluated the prognostic role of heart failure hospitalization in patients with advanced heart failure.

Methods
The multicenter HELP-HF registry enrolled consecutive patients with heart failure and at least one high-risk ‘I NEED HELP’ marker. Characteristics and outcomes were compared between patients who were hospitalized for decompensated heart failure (inpatients) or not (outpatients) at the time of enrolment. The primary endpoint was the composite of all-cause mortality or first heart failure hospitalization.

Results
Among the 1149 patients included [mean age 75.1 ± 11.5 years, 67.3% men, median left ventricular ejection fraction (LVEF) 35% (IQR 25–50%)], 777 (67.6%) were inpatients at the time of enrolment. As compared with outpatients, inpatients had lower LVEF, higher natriuretic peptides and a worse clinical profile. The 1-year rate of the primary endpoint was 50.9% in inpatients versus 36.8% in outpatients [crude hazard ratio 1.70, 95% confidence interval (CI) 1.39–2.07, P < 0.001]. At multivariable analysis, inpatient status was independently associated with a higher risk of the primary endpoint (adjusted hazard ratio 1.54, 95% CI 1.23–1.93, P < 0.001). Among inpatients, the independent predictors of the primary endpoint were older age, lower SBP, heart failure association criteria for advanced heart failure and glomerular filtration rate 30 ml/min/1.73 m2 or less.

Conclusion
Hospitalization for heart failure in patients with at least one high-risk ‘I NEED HELP’ marker is associated with an extremely poor prognosis supporting the need for specific interventions, such as mechanical circulatory support or heart transplantation.
Next-generation sequencing-based liquid biopsy may be used for detection of residual disease and cancer recurrence monitoring in dogs
Authors: McCleary-Wheeler Angela L. , Fiaux Patrick C. , Flesner Brian K. , Ruiz-Perez Carlos A. , McLennan Lisa M. , Tynan John A. , Hicks Susan C. , Rafalko Jill M. , Grosu Daniel S. , Chibuk Jason , O'Kell Allison L. , Cohen Todd A. , Chorny Ilya , Tsui Dana W.Y. , Kruglyak Kristina M. , Flory Andi 
Published: December 2023

Abstract

OBJECTIVE
The purpose of this study was to evaluate the performance of a next-generation sequencing-based liquid biopsy test for cancer monitoring in dogs.

SAMPLES
Pre- and postoperative blood samples were collected from dogs with confirmed cancer diagnoses originally enrolled in the CANcer Detection in Dogs (CANDiD) study. A subset of dogs also had longitudinal blood samples collected for recurrence monitoring.

METHODS
All cancer-diagnosed patients had a preoperative blood sample in which a cancer signal was detected and had at least 1 postoperative sample collected. Clinical data were used to assign a clinical disease status for each follow-up visit.

RESULTS
Following excisional surgery, in the absence of clinical residual disease at the postoperative visit, patients with Cancer Signal Detected results at that visit were 1.94 times as likely (95% CI, 1.21 to 3.12; P = .013) to have clinical recurrence within 6 months compared to patients with Cancer Signal Not Detected results. In the subset of patients with longitudinal liquid biopsy samples that had clinical recurrence documented during the study period, 82% (9/11; 95% CI, 48% to 97%) had Cancer Signal Detected in blood prior to or concomitant with clinical recurrence; in the 6 patients where molecular recurrence was detected prior to clinical recurrence, the median lead time was 168 days (range, 47 to 238).

CLINICAL RELEVANCE
Next-generation sequencing-based liquid biopsy is a noninvasive tool that may offer utility as an adjunct to current standard-of-care clinical assessment for cancer monitoring; further studies are needed to confirm diagnostic accuracy in a larger population.
Exposure to emulsified isoflurane and sevoflurane protects canine primary hepatocytes against hypoxia-induced apoptosis
Authors: Obeid Patricia de Carvalho Ibrahim , Natalini Claudio Correa , Howell George Eli 
Published: December 2023

Abstract

OBJECTIVE
Emulsified isoflurane and sevoflurane have immunomodulating and anti-inflammatory effects in vital organs such as the brain, myocardium, and kidneys subjected to ischemia-reperfusion injury. This study aims to investigate the cellular protective effects of both emulsified anesthetics in cultured canine hepatocytes.

PROCEDURES
We analyzed the apoptosis and viability responses of cultured primary canine hepatocytes exposed to 1% O2 for 30 versus 120 minutes after being treated with emulsified isoflurane or sevoflurane in 10% lipid, or 10% lipid alone or no-treatment control at 24 hours of reoxygenation (21% O2).

RESULTS
After 120 minutes of hypoxia, the hepatocytes that received either emulsified isoflurane or sevoflurane treatments had significantly decreased apoptosis at 24 hours of reoxygenation in comparison to the 10% lipid treatment. Also, the no-treatment control group had significantly higher apoptosis at 24 hours of reoxygenation when exposed to 120 minutes of hypoxia compared to 30 minutes of hypoxia. Neither 30 nor 120 minutes of hypoxia or exposure to 10% lipid, emulsified isoflurane, or emulsified sevoflurane altered overall cellular viability at 24 hours of reoxygenation.

CLINICAL RELEVANCE
This study demonstrated that both isoflurane and sevoflurane, in the emulsified form, have the potential to reduce the apoptotic response of cells under oxygen deprivation. Therefore, this attribute of both halogenated anesthetics suggests an alternative treatment to be applied in live patients submitted to surgical stabilization of organs and tissues under the risk of ischemia and reperfusion injury.
Predicting an increased risk of severe clinical mastitis and economic loss using a threshold value of bovine leukemia virus proviral load
Authors: Watanabe Aiko , Murakami Hironobu , Kakinuma Seiichi , Murao Koki , Oomae Kaori , Akamatsu Hirohisa , Seto Takahiro , Shinozuka Yasunori , Kawai Kazuhiro 
Published: December 2023

Abstract

OBJECTIVE
To establish a threshold value of bovine leukemia virus (BLV) proviral load (PVL) to identify increased risk of severe clinical mastitis, and to examine the prognosis and economic loss of clinical mastitis based on the newly established PVL cut-off value.

ANIMALS
97 lactating Holstein cows with clinical mastitis.

METHODS
Blood and milk samples were collected aseptically from each cow. Youden index was used for receiver-operating characteristic curve analysis with the severity rate of clinical mastitis as the dependent variable and PVL as an independent variable. PVL cut-off value was used as a criterion to compare the severity rate of clinical mastitis, percentage of cows with and without systemic treatments, number of treatments, cost of treatment, and prognosis.

RESULTS
PVL cut-off value was 17.8 copies/10 ng DNA for the dependent variable MILD vs SEVERE. The severity rate of clinical mastitis, percentage of cows given systemic treatments, and technical fees for medical treatment were significantly higher in the group above the PVL cut-off value than in the group below the PVL cut-off value and the negative group. Number of treatments was significantly higher in the group above the cut-off value than in the group below the cut-off value. There was no significant difference in prognosis after mastitis among the 3 groups.

CLINICAL RELEVANCE
These results suggested that PVL cut-off value of 17.8 copies/10 ng DNA was a useful threshold for increased economic losses in BLV-infected cows; it may also serve as a new standard value for the detection and culling of BLV-infected cows in Japan.