bluuebunny/crossref_metadata_2025_split huggingface dataset:
Picking Your Tick: Toward a New Theory of Stock Splits
Authors: Angel James J. 
Published: April 2005

Thanks to stock splits, the average nominal share price has been amazingly stable in the United States. The average NYSE share price has fluctuated within the $30 to $40 range since the late 1930s—a period in which most consumer prices have increased by a factor of 10 and the S&P index has risen over 1,500%. Why has this nominal price been so stable when every other price has increased so much?And why do typical stock prices vary so greatly among different countries? For example, the median nominal stock price ranges from about $2 in Hong Kong and $7 in the U.K., to $103 in France and over $600 in Switzerland.The author's recent research suggests that typical stock prices vary across countries in ways that reflect primarily differences in how markets in each country set their “tick” rules—the rules governing the minimum price variation that can occur in a stock (in the U.S., for example, the tick was recently reduced from $1/8 to $1/16). Companies, on average, appear to respond to the resulting differences in tick size by adjusting the number of their shares outstanding so that the tick size relative to the nominal share price remains relatively constant. In fact, a tick size equal to about 25 basis points of the median share price “appears to be a universal norm” across global markets.This article explores how and why a company might wish to affect the relative tick size for its stock by splitting—and, in so doing, it suggests a “new theory” of stock splits. The theory also suggests that the optimal tick size for any given company will vary according to its size, visibility, and riskiness.
How To Choose a Capital Structure: Navigating the Debt‐Equity Decision
Authors: Shivdasani Anil , Zenner Marc 
Published: April 2005

In corporate offices as well as the classroom, there continues to be significant debate about the costs and benefits of debt financing. There is also considerable variation in corporate credit ratings, even among companies as large and successful as those that make up the S&P 500. Many companies have been reassessing how they manage their balance sheet and their rating agency relationships; and with the market's generally favorable response to recapitalizations and dividend increases, such financing issues are likely to receive even more attention.Underlying the diversity of corporate credit ratings is widespread disagreement about the “right” credit rating—a matter that is complicated by the fact that the cost of debt varies widely among companies with the same rating. Although credit ratings are clearly tied to measures of indebtedness such as leverage and coverage ratios, the most important factor in most industries is a company's size. For many mid‐sized companies, an investment‐grade rating can be attained only by making a large, equity‐financed acquisition—or by making minimal use of debt. In this sense, the corporate choice of credit rating can be as much a strategic issue as a financial decision.Maintaining the right amount of financial fl exibility is a key consideration when determining the right credit rating for a given company (although what management views as value‐preserving flexibility may be viewed by the market as value‐reducing financial “slack”). A BBB rating will accommodate considerably more leverage (30–60%) in companies with fairly stable cash flows and limited investment requirements than in more cyclical or growth‐oriented companies (10–20%). When contemplating taking on more leverage, companies should examine all major operating risks and view their capital structure in the context of an enterprisewide risk management framework.
Transcriptional Response of
Saccharomyces cerevisiae
to the Plasma Membrane-Perturbing Compound Chitosan
Authors: Zakrzewska Anna , Boorsma Andre , Brul Stanley , Hellingwerf Klaas J. , Klis Frans M. 
Published: April 2005

ABSTRACT

Chitosan is a plasma membrane-perturbing compound consisting of linear chains of β-1,4-linked glucosamine residues, which at acidic pHs become positively charged. It is extensively used as an antimicrobial compound, yet its mode of action is still unresolved. Chitosan strongly affected the growth of the yeast
Saccharomyces cerevisiae
, the food spoilage yeast
Zygosaccharomyces bailii
, and two human-pathogenic yeasts,
Candida albicans
and
Candida glabrata
. Microarray analysis of yeast cells treated with sublethal concentrations of chitosan revealed induction of the environmental stress response and three more major transcriptional responses. The first was a rapid and stable Cin5p-mediated response. Cin5p/Yap4p is a transcription factor involved in various stress responses. Deletion of
CIN5
led to increased chitosan sensitivity. The second was a Crz1p-mediated response, which is delayed compared to the Cin5p response. Crz1p is a transcription factor of the calcineurin pathway. Cells deleted for
CRZ1
or treated with the calcineurin inhibitor FK506 became hypersensitive to chitosan, supporting the notion that the Crz1p-controlled response offers protection against chitosan. The third was a strong Rlm1p-mediated response which ran parallel in time with the Crz1p-regulated response. Rlm1p is a transcription factor of the cell wall integrity pathway, which is activated by cell wall stress. Importantly, chitosan-treated cells became more resistant to β-1,3-glucanase, which is a well-known response to cell wall stress. We propose that the transcriptional response to chitosan may be representative of other plasma membrane-perturbing compounds.
Role of Snf1p in Regulation of Intracellular Sorting of the Lactose and Galactose Transporter Lac12p in
Kluyveromyces lactis
Authors: Wiedemuth Christian , Breunig Karin D. 
Published: April 2005

ABSTRACT

The protein kinase Snf1/AMPK plays a central role in carbon and energy homeostasis in yeasts and higher eukaryotes. To work out which aspects of the Snf1-controlled regulatory network are conserved in evolution, the Snf1 requirement in galactose metabolism was analyzed in the yeast
Kluyveromyces lactis
. Whereas galactose induction was only delayed,
K. lactis snf1
mutants failed to accumulate the lactose/galactose H
+
symporter Lac12p in the plasma membran,e as indicated by Lac12-green fluorescent protein fusions. In contrast to wild-type cells, the fusion protein was mostly intracellular in the mutant. Growth on galactose and galactose uptake could be restored by the
KHT3
gene, which encodes a new transporter of the
HXT
subfamily of major facilitators These findings indicate a new role of Snf1p in regulation of sugar transport in
K. lactis
.
Effect of the Major Repeat Sequence on Chromosome Loss in
Candida albicans
Authors: Lephart Paul R. , Chibana Hiroji , Magee Paul T. 
Published: April 2005

ABSTRACT

The major repeat sequence (MRS) is found at least once on all but one chromosome in
Candida albicans
, but as yet it has no known relation to the phenotype. The MRS affects karyotypic variation by serving as a hot spot for chromosome translocation and by expanding and contracting internal repeats, thereby changing chromosome length. Thus, MRSs on different chromosomes and those on chromosome homologues can differ in size. We proposed that the MRS's unique repeat structure and, more specifically, the size of the MRS could also affect karyotypic variation by altering the frequency of mitotic nondisjunction. Subsequent analysis shows that both natural and artificially induced differences in the size of the chromosome 5 MRS can affect chromosome segregation. Strains with chromosome 5 homologues that differ in the size of the naturally occurring MRSs show a preferential loss of the homologue with the larger MRS on sorbose, indicating that a larger MRS leads to a higher risk of mitotic nondisjunction for that homologue. While deletion of an MRS has no deleterious effect on the deletion chromosome under normal growth conditions and leads to no obvious phenotype, strains that have the MRS deleted from one chromosome 5 homologue preferentially lose the homologue with the MRS remaining. This effect on chromosome segregation is the first demonstration of a phenotype associated with the MRS.
A Point Mutation in the Cargo-Binding Domain of Myosin V Affects Its Interaction with Multiple Cargoes
Authors: Pashkova Natasha , Catlett Natalie L. , Novak Jennifer L. , Weisman Lois S. 
Published: April 2005

ABSTRACT

Class V myosins move diverse intracellular cargoes, which attach via interaction of cargo-specific proteins to the myosin V globular tail. The globular tail of the yeast myosin V, Myo2p, contains two structural and functional subdomains. Subdomain I binds to the vacuole-specific protein, Vac17p, while subdomain II likely binds to an as yet unidentified secretory vesicle-specific protein. All functions of Myo2p require the tight association of subdomains I and II, which suggests that binding of a cargo to one subdomain may inhibit cargo-binding to a second subdomain. Thus, two types of mutations are predicted to specifically affect a subset of Myo2p cargoes: first are mutations within a cargo-specific binding region; second are mutations that mimic the inhibited conformation of one of the subdomains. Here we analyze a point mutation in subdomain I,
myo2-2
(
G1248D
), which is likely to be this latter type of mutation.
myo2-2
has no effect on secretory vesicle movement. The secretory vesicle binding site is in subdomain II. However,
myo2-2
is impaired in several Myo2p-related functions. While subdomains I and II of myo2-2p tightly associate, there are measurable differences in the conformation of its globular tail. Based solely on the ability to restore vacuole inheritance, a set of intragenic suppressors of
myo2-2
were identified. All suppressor mutations reside in subdomain I. Moreover, subdomain I and II interactions occurred in all suppressors, demonstrating the importance of subdomain I and II association for Myo2p function. Furthermore, 3 of the 10 suppressors globally restored all tested defects in
myo2-2
. This large proportion of global suppressors strongly suggests that
myo2-2
(
G1248
) causes a conformational change in subdomain I that simultaneously affects multiple cargoes.
The Natural World in the Sermons of Eusebius of Emesa
Authors: Winn Robert 
Published: April 2005

AbstractIn his extant sermons, Eusebius of Emesa rejected the use of natural analogies, such as the sun and its light, to clarify the relationship between the Father and the Son. This is remarkable not only because he was otherwise committed to the theological tradition of Origen as mediated through Eusebius of Caesarea, both of whom used such analogies, but also because he was willing to direct his audiences' attention to the natural world in many of his sermons to establish other theological positions of the church. In this article I will argue that his rejection of natural analogies in this instance must be understood in the broader context of his use of nature in general in his sermons. I conclude that his affirmation or denial of the usefulness of the natural world depended on whether it would affirm or undermine the religious identity of the church.
Malalas, "Constantius", and a Church-inscription from Antioch
Authors: Woods David 
Published: April 2005

AbstractJohn Malalas (Chron. 13.17) does not preserve the dedicatory inscription from the Great Church of Antioch dedicated in 341, despite his claim to this effect, and there is no need to emend his transmitted text in order to force it to fit this interpretation. Instead, it was the praepositus sacri cubiculi Gorgonius who had these verses inscribed, probably on some gift which he made to the martyrium of bishop Babylas, or the church that was transformed into such subsequently, sometime during Gallus Caesar's brief reign 351-54. Malalas has misunderstood his literary source for this inscription.
Lidar and Triple-Wavelength Doppler Radar Measurements of the Melting Layer: A Revised Model for Dark- and Brightband Phenomena
Authors: Sassen Kenneth , Campbell James R. , Zhu Jiang , Kollias Pavlos , Shupe Matthew , Williams Christopher 
Published: April 2005

Abstract
During the recent Cirrus Regional Study of Tropical Anvils and Cirrus Layers (CRYSTAL) Florida Area Cirrus Experiment (FACE) field campaign in southern Florida, rain showers were probed by a 0.523-μm lidar and three (0.32-, 0.86-, and 10.6-cm wavelength) Doppler radars. The full repertoire of backscattering phenomena was observed in the melting region, that is, the various lidar and radar dark and bright bands. In contrast to the ubiquitous 10.6-cm (S band) radar bright band, only intermittent evidence is found at 0.86 cm (K band), and no clear examples of the radar bright band are seen at 0.32 cm (W band), because of the dominance of non-Rayleigh scattering effects. Analysis also reveals that the relatively inconspicuous W-band radar dark band is due to non-Rayleigh effects in large water-coated snowflakes that are high in the melting layer. The lidar dark band exclusively involves mixed-phase particles and is centered where the shrinking snowflakes collapse into raindrops—the point at which spherical particle backscattering mechanisms first come into prominence during snowflake melting. The traditional (S band) radar brightband peak occurs low in the melting region, just above the lidar dark-band minimum. This position is close to where the W-band reflectivities and Doppler velocities reach their plateaus but is well above the height at which the S-band Doppler velocities stop increasing. Thus, the classic radar bright band is dominated by Rayleigh dielectric scattering effects in the few largest melting snowflakes.
Differences of Rainfall Estimates over Land by Tropical Rainfall Measuring Mission (TRMM) Precipitation Radar (PR) and TRMM Microwave Imager (TMI)—Dependence on Storm Height
Authors: Furuzawa Fumie A. , Nakamura Kenji 
Published: April 2005

Abstract
It is well known that precipitation rate estimation is poor over land. Using the Tropical Rainfall Measuring Mission (TRMM) precipitation radar (PR) and TRMM Microwave Imager (TMI), the performance of the TMI rain estimation was investigated. Their differences over land were checked by using the orbit-by-orbit data for June 1998, December 1998, January 1999, and February 1999, and the following results were obtained: 1) Rain rate (RR) near the surface for the TMI (TMI-RR) is smaller than that for the PR (PR-RR) in winter; it is also smaller from 0900 to 1800 LT. These dependencies show some variations at various latitudes or local times. 2) When the storm height is low (&lt;5 km), the TMI-RR is smaller than the PR-RR; when it is high (&gt;8 km), the PR-RR is smaller. These dependencies of the RR on the storm height do not depend on local time or latitude. The tendency for a TMI-RR to be smaller when the storm height is low is more noticeable in convective rain than in stratiform rain. 3) Rain with a low storm height predominates in winter or from 0600 to 1500 LT, and convective rain occurs frequently from 1200 to 2100 LT. Result 1 can be explained by results 2 and 3. It can be concluded that the TMI underestimates rain with low storm height over land because of the weakness of the TMI algorithm, especially for convective rain. On the other hand, it is speculated that TMI overestimates rain with high storm height because of the effect of anvil rain with low brightness temperatures at high frequencies without rain near the surface, and because of the effect of evaporation or tilting, which is indicated by a PR profile and does not appear in the TMI profile. Moreover, it was found that the PR rain for the cases with no TMI rain amounted to about 10%–30% of the total but that the TMI rain for the cases with no PR rain accounted for only a few percent of the TMI rain. This result can be explained by the difficulty of detecting shallow rain with the TMI.
A Numerical Study on the Interpretation of Data from Open Atmospheric Balloon Soundings
Authors: Alexander P. 
Published: April 2005

Abstract
Wrong information may be extracted from balloon soundings if neither appropriate interpretation and processing nor evaluations of certain inevitable distortions or artifacts on atmospheric measurements are performed. A numerical code that finds solutions to the dynamical and thermal equations describing an open balloon in the atmosphere is used to develop flight simulations under diverse conditions. The results are then employed to point out that a valid determination of values for diverse variables is intrinsically difficult. It is shown that the distance between the balloon and gondola may be chosen to optimize the information to be obtained from observations obtained during ascent and descent, so that even without an accurate balloon-tracking system, it may be possible to reconstruct horizontal wind fluctuations from the measurements. Vertical air oscillations may be only grossly inferred in some cases. The propagation direction of gravity waves detected during a sounding may be inferred and vertical wavelengths may typically be determined with a 10% accuracy. Air velocity measurements performed during flotation may be used to find shears.
Simulations of Dynamics and Transport during the September 2002 Antarctic Major Warming
Authors: Manney Gloria L. , Sabutis Joseph L. , Allen Douglas R. , Lahoz William A. , Scaife Adam A. , Randall Cora E. , Pawson Steven , Naujokat Barbara , Swinbank Richard 
Published: April 2005

Abstract
A mechanistic model simulation initialized on 14 September 2002, forced by 100-hPa geopotential heights from Met Office analyses, reproduced the dynamical features of the 2002 Antarctic major warming. The vortex split on ∼25 September; recovery after the warming, westward and equatorward tilting vortices, and strong baroclinic zones in temperature associated with a dipole pattern of upward and downward vertical velocities were all captured in the simulation. Model results and analyses show a pattern of strong upward wave propagation throughout the warming, with zonal wind deceleration throughout the stratosphere at high latitudes before the vortex split, continuing in the middle and upper stratosphere and spreading to lower latitudes after the split. Three-dimensional Eliassen–Palm fluxes show the largest upward and poleward wave propagation in the 0°–90°E sector prior to the vortex split (coincident with the location of strongest cyclogenesis at the model’s lower boundary), with an additional region of strong upward propagation developing near 180°–270°E. These characteristics are similar to those of Arctic wave-2 major warmings, except that during this warming, the vortex did not split below ∼600 K. The effects of poleward transport and mixing dominate modeled trace gas evolution through most of the mid- to high-latitude stratosphere, with a core region in the lower-stratospheric vortex where enhanced descent dominates and the vortex remains isolated. Strongly tilted vortices led to low-latitude air overlying vortex air, resulting in highly unusual trace gas profiles. Simulations driven with several meteorological datasets reproduced the major warming, but in others, stronger latitudinal gradients at high latitudes at the model boundary resulted in simulations without a complete vortex split in the midstratosphere. Numerous tests indicate very high sensitivity to the boundary fields, especially the wave-2 amplitude. Major warmings occurred for initial fields with stronger winds and larger vortices, but not smaller vortices, consistent with the initiation of wind deceleration by upward-propagating waves near the poleward edge of the region where wave 2 can propagate above the jet core. Thus, given the observed 100-hPa boundary forcing, stratospheric preconditioning is not needed to reproduce a major warming similar to that observed. The anomalously strong forcing in the lower stratosphere can be viewed as the primary direct cause of the major warming.
An Observational Study of the Final Breakdown of the Southern Hemisphere Stratospheric Vortex in 2002
Authors: Orsolini Yvan J. , Randall Cora E. , Manney Gloria L. , Allen Douglas R. 
Published: April 2005

Abstract
The 2002 Southern Hemisphere final warming occurred early, following an unusually active winter and the first recorded major warming in the Antarctic. The breakdown of the stratospheric polar vortex in October and November 2002 is examined using new satellite observations from the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS) instrument aboard the European Space Agency (ESA) Environment Satellite (ENVISAT) and meteorological analyses, both high-resolution fields from the European Centre for Medium-Range Weather Forecasts and the coarser Met Office analyses. The results derived from MIPAS observations are compared to measurements and inferences from well-validated solar occultation satellite instruments [Halogen Occultation Experiment (HALOE), Polar Ozone and Aerosol Measurement III (POAM III), and Stratospheric Aerosol and Gas Experiments II and III (SAGE II and III)] and to finescale tracer fields reconstructed by transporting trace gases based on MIPAS or climatological data using a reverse-trajectory method. These comparisons confirm the features in the MIPAS data and the interpretation of the evolution of the flow during the vortex decay revealed by those features. Mapped ozone and water vapor from MIPAS and the analyzed isentropic potential vorticity vividly display the vortex breakdown, which occurred earlier than usual. A large tongue of vortex air was pulled out westward and coiled up in an anticyclone, while the vortex core remnant shrank and drifted eastward and equatorward over the South Atlantic. By roughly mid-November, the vortex remnant at 10 mb had shrunk below scales resolved by the satellite observations, while a vortex core remained in the lower stratosphere.
Has the Antarctic Vortex Split before 2002?
Authors: Roscoe H. K. , Shanklin J. D. , Colwell S. R. 
Published: April 2005

AbstractIn late September 2002, the Antarctic ozone hole was seen to split into two parts, resulting in large increases in ozone at some stations and the potential for significant modification of chlorofluorocarbon (CFC)-induced ozone loss. The phenomenon was dynamical (a split vortex), causing large increases in stratospheric temperature above stations normally within the vortex. Temperatures at Halley, Antarctica, at 30 hPa increased by over 60 K, and temperatures at South Pole at 100 hPa increased by over 25 K. It is important to know if this has happened before, since if it happens in the future, it would significantly alter the total hemispheric ozone loss due to chlorine from CFCs, particularly if it happens in August or September. Temperatures in winter and spring measured at Halley or the South Pole since 1957 and 1961, respectively, show no other comparable increases until the final warming in late spring, except for two dates in the 1980s at Halley when meteorological analyses show no vortex split. There are very few periods of measurements missing at both Halley and the South Pole, and analyses in those few periods show no vortex split. Measurements in August and September at sites normally near the edge of the vortex show very few suspicious dates, and analyses of those few suspicious dates again show no vortex split. It is concluded that the vortex has probably not split before the final warming since Antarctic records began in the late 1950s, and almost certainly not in August or September.