bluuebunny/crossref_metadata_2025_split huggingface dataset:
Knowledge and awareness of autism spectrum disorder among Libyans
Authors: Mustafa Ariej M. , Grifa Dhiba , Shebani Afaf , Alharabi Salah , Alnajjar Khalid 
Published: January 2024

Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by the presence of delayed or defective development before the age of three years, as well as behavioral difficulties in social communication and interaction.
Objective: To evaluate ASD knowledge and awareness, as well as ASD information sources in a sample of the Libyan general population, and to explore factors that could be associated with the knowledge and awareness.
Methods: A cross-sectional study was carried out between 22 March and 13 August 2022 using a self-administered questionnaire.
Results: Out of 2195 participants, 48.9% were females and 51.1% were males. Three-quarters of the participants (74.8%) presented a low level of knowledge. Of those whose source of knowledge of autism was social media, 78.9% had a low level of knowledge. However, 57.9% of the participants showed a good level of awareness of autism symptoms and signs.
Conclusion: The participants had a limited understanding of the causes and characteristics of ASD. Raising community awareness of the causes and characteristics of ASD is a priority.
Factors associated with mortality among patients with tuberculosis in a tertiary hospital in South West Nigeria
Authors: Odeyemi Abimbola Ololade , Odeyemi Abiona Oluwadamilola , Ojewuyi Abiodun Ronke , Olasinde Yetunde Toyin , Oni Opeyemi Olalekan , Ojo Oluwafemi Tunde 
Published: January 2024

Abstract

Background:
Tuberculosis (TB) is a significant cause of morbidity and mortality, particularly in developing countries.

Objective:
To identify the factors contributing to TB mortality.

Materials and Methods:
This is a retrospective review of TB patients managed at the TB Clinic of a Teaching Hospital in Southwest Nigeria, from January 2015 to December 2021. The patient’s demographic characteristics, TB type, and coinfection with human immunodeficiency virus (HIV) were studied. The factors associated with mortality were examined.

Results:
1259 TB cases were studied, with a mean (standard deviation) age of 42.6 (16.33) years. There was a male predominance of 64.9%. One hundred and fifty-one subjects died while receiving treatment; hence, the mortality rate was 12.0%. Age (P: 0.000), HIV status (P: 0.028), sputum smear-negative (P: 0.038), and extra-pulmonary TB (P: 0.019) were factors with statistically significant association with TB mortality. Older age (odds ratio [OR]: 1.017, 95% confidence interval [CI]: 1.007–1.028, P: 0.001) and HIV-positive status (OR: 1.911, 95% CI: 1.083–3.372, P: 0.025) were found to be independently associated with TB mortality.

Conclusion:
The proportion of patients who die during TB treatment is still high, particularly among those with older age (>60 years) and those with HIV coinfection. Prevention of HIV infection will have a substantial impact on the reduction of TB burden and mortality. More attention should be given to TB patients who are elderly and those with HIV/TB coinfection in order to improve the disease outcome.
Study of the antibiotic-resistant Escherichia coli isolated from urinary tract
Authors: Al-Khikani Falah Hasan Obayes 
Published: January 2024

Abstract

Background:

Escherichia coli is a common bacteria that can be pathogenic and develop resistance to various antibiotics in different ways, making them difficult to treat with standard therapies. So, monitoring antibiotic resistance is urgent.

Materials and Methods:

Escherichia coli was isolated from the urinary tract and cultured in three media (blood agar, McConkey agar, and EMB agar), then they were incubated for 24 h at a temperature of 37oC to grow. The antibiotics discs (Ciprofloxacin, Gentamicin) were used by disc diffusion method. All the statistical analysis was done by using SPSS 26 software and the Excel app.

Results:
The participants in this study were 70% women, while 30% were men, with significant differences (P < 0.05). Gentamicin showed a high rate of sensitivity (85%). The sensitive isolates to ciprofloxacin were 75%.

Conclusions:
We have found that 85% of bacteria are sensitive to gentamicin, and thus, it can be used as an empirical treatment. Ciprofloxacin showed a high rate of sensitivity against E. coli, 75%.
Serial analysis of hematological, biochemical, and immunological parameters alterations in regular healthy voluntary donors during plateletpheresis donation
Authors: Hans Rekha , Pahwa Deepak , Paul Preeti , Kaur Jyotdeep , Saikia Biman , Sharma Ratti Ram , Marwaha Neelam 
Published: January 2024

Abstract

BACKGROUND AND OBJECTIVES:
The long-term effect of regular plateletpheresis on donors has not been characterized. Hence, we planned to study the long-term alterations in hematological, biochemical, and immunological parameters in regular repeat platelet apheresis donors.

MATERIALS AND METHODS:
Thirty-three healthy voluntary regular repeat apheresis donors presenting for platelet donation, fulfilling the requisite donor selection criteria, underwent sequential analysis of the hematological, biochemical, and immunological parameters over 1 year.

RESULTS:
A total of 33 regular repeat donors were enrolled in the study; out of these, 22 could be followed up to 3 months, 12 up to 6 months, and 10 donors up to 12 months for their hematological, biochemical, and immunological parameters. Overall, there was no significant change in hematological profile except a rise in platelet count at 3 months (P = 0.023) with no significant difference at 6 and 12 months from the baseline. In addition, serum thrombopoietin levels at 3 months (P = 0.010) and serum erythropoietin at 6 months (P = 0.01) were significantly higher than baseline. Mean platelet volume was significantly higher from baseline at 12 months (P = 0.00). Serum protein, lymphocyte subpopulation, and serum ferritin did not show any significant change from baseline over 12 months of follow-up. However, there was a significant decline (P = 0.00) in serum calcium and an increase in serum magnesium from baseline (P = 0.03) at 12 months.

INTERPRETATIONS AND CONCLUSIONS:
To conclude, apheresis platelet donation is a safe procedure. However, a complete hematological, biochemical, immunological profile and bone marrow density at regular intervals (3–6 months) are recommended to ensure the safety of regular repeat plateletpheresis donors.
Autologous blood transfusion in a neurosurgical patient with multiple alloantibodies
Authors: Sam Angel Mary , Nair Amita Radhakrishnan , Gupta Debasish 
Published: January 2024

Abstract
There are many challenges to obtain antigen-negative, crossmatch compatible blood for a patient with multiple alloantibodies. We present a case report of a 31-year-old female patient with a recurrent pontine cavernoma who was to undergo a neurosurgical procedure. We identified alloantibodies anti-Fya and anti-c in her blood sample. To meet her intraoperative blood requirement, we attempted with autologous blood transfusion using both predeposit autologous donation and acute normovolemic hemodilution. Autologous blood alone was sufficient despite anticipating surgical blood loss and a postoperative surgical site infection.
Implementation of an international barcode labeling standard, International Society of Blood Transfusion 128, and its integration with local regulations at a blood center in India: Step-by-step journey
Authors: Aggarwal Geet , Tiwari Aseem Kumar , Pabbi Swati , Bhardwaj Gunjan , Khurana Naresh , Rawat Ganesh , Joseph Nixon P. 
Published: January 2024

Abstract
The International Society of Blood Transfusion (ISBT) 128 is an internationally endorsed, electronically readable labeling standard that provides a convenient and accurate means of identification, traceability, publication, and storage of information for blood and blood products. The authors’ center recently registered with the International Council for Commonality in Blood Banking Automation (ICCBBA) and progressed to ISBT 128 labeling standard. This manuscript was written with the objective of sharing the authors’ experience with respect to the implementation of ISBT 128 standards for whole blood donations and integration of ISBT 128 standards with Indian licensing regulations. The authors explore the process of implementation of ISBT 128 standards through a step-by-step journey that included facility registration with International Council for Commonality in Blood Banking Automation (ICCBBA), allotment of facility identification number, development of four-quadrant label for blood components, and integration of local regulatory requirements in the final “composite” label. Acknowledging the lack of any published report from India on ISBT 128 standards implementation, the authors wish to attempt help their peers in understanding and implementation of this global standard at their respective facilities.
Numerical Modelling of Stone Lofting by a Treaded Tyre
Authors: Kumar Sourav , Babbar Ritvik , Pattankar Rohan , Venkatarama Nithin , Yenugu Srinivasa , Duggirala Ravi 
Published: January 2024

<div class="section abstract"><div class="htmlview paragraph">In passenger cars, exterior damage due to external objects is a common and repetitive problem for the costumer. A vehicle running over an unpaved or granular road undergoes such damages where the tyre picks up stones (<span class="xref">Figure 1</span>) [<span class="xref">1</span>] and ejects them towards the vehicle exterior surfaces. These stones cause mechanical damage to the vehicle: affecting aesthetics, accelerating corrosion, and reducing safety. This mechanical damage is more severe in case of electrical vehicles as batteries are placed at the underside of the vehicle. <span class="xref">Figure 2</span> [<span class="xref">2</span>] shows an example damaged caused by stone chipping. Induced erosion due to chipping cause corrosion propagation on the peeled surface, <span class="xref">Figure 2</span> shows an example of such corrosion. So far, physical testing and analytical mathematical methods are the most common ways to evaluate damages. However, there is a need of computationally inexpensive, repeatable, and accurate method, which can account for the complex system. This paper describes a validated Multiphysics numerical model for stone lofting, using a stand- alone all-weather tyre. The presented Multiphysics model couples Discrete Element Method (DEM), Finite Element Method (FEM), Multi-body Dynamics (MBD). Results of this work correlate well with experimental findings from Andreas Schönberger [<span class="xref">3</span>]. These experiments were performed in a controlled environment with a standalone treaded tyre and for three different velocities of 30kmph, 50kmph and 80kmph which accounts for tyre rotation. The results presented in this work show that method used is capable to capture relevant physics and predict stone lofting numerically. This method is anticipated as a starting point for the development of more sophisticated numeric models for stone chipping prediction.</div></div>
The use of corn and buckwheat flour in the production of bakery products
Authors: Efremova E. N. , Belyaev A. I. , Petrov N. Y. , Zenina E. A. 
Published: January 2024

Currently, to make profit all entrepreneurs expand the range of products. The purpose of the research is introduction and use of a combination of different types of flour in bread baking in order to expand the range of bakery products of improved quality. The objectives of the research are to study the organoleptic quality indicators of the experimental sample; to conduct a study on physical and chemical quality indicators of the experimental sample; to determine the economic feasibility of using a new recipe in bread production. The research was carried out on the basis of the Department of Processing Technologies and Food Security of Volgograd State Agrarian University. To expand the range of bakery products, 40% of corn flour and 10% of buckwheat flour were used to replace 50% of wheat flour. The bread was baked using the non-steam method. When conducting an organoleptic assessment of bread, the experimental sample complied with the requirements of GOST 27669-88 «Wheat baking flour. Method of trial laboratory bread baking.» The taste became sweeter, the porosity became fine and thin-walled, and the color of the crumb became light brown. According to physicochemical indicators, the experimental sample was 56 g larger in bread volume, and the crumb moisture content was 43%. The economic efficiency of bread production was calculated. The profitability of experimental bread production was 44%, which was 14% higher than the control (wheat) sample. I t is recommended to produce bread using a combination of three types of flour, to increase the output at enterprises. This type of bread, in terms of organoleptic and physico-chemical indicators, has proven itself to be a more advantageous example of a bakery product compared with wheat bread.
ИЗУЧЕНИЕ ФАКТОРОВ ВЛИЯЮЩИХ НА РАЗВИТИЕ ТРЕВОЖНЫХ СОСТОЯНИЙ У БОЛЬНЫХ, ПЕРЕНЕСШИХ COVID-19
Authors: Восиков Ботирбек , Магзумова Шахноза 
Published: January 2024

За последние десятилетия значительно возрос научный интерес к проблеме тревожных расстройств. Тревожные расстройства являются одним из наиболее распространенных психических заболеваний, которые могут возникнуть в ответ на стрессовые ситуации, такие как пандемия. Тревожные расстройства могут привести к серьезным последствиям для здоровья, таким как снижение иммунитета, проблемы со сном, панические атаки и депрессия. В данной статье представлены данные исследования проведенного на базе Городской клинической психиатрической больницы с целью выявить факторов влияющих на развитие тревожных расстройств.
AKUSHERLIK VA GINEKOLOGIYADA BIRIKTIRUVCHI TOʻQIMA DIFFERENSIALLASHMAGAN DISPLAZIYASI DIAGNOTIKASINING JIHATLARI
Authors: Bektemirova Begoyim , Saidjalilova Dilnoza 
Published: January 2024

Tadqiqotning maqsadi biriktiruvchi toʻqima differensiallashmagan displaziyasi (BTDD) mavjud homiladorlarda biriktiruvchi toʻqima metabolizmi biokimyoviy markerlari – qondagi magniy va oksiprolin miqdorini aniqlashning samaradorligini aniqlash va buni magniy preparatlari bilan davolash yordamida tekshirishdan iborat. Tadqiqot Toshkent shahar 9-Akusherlik kompleksida oʻtkazilgan. Unga 129 ta ayol qamrab olindi. Ulardan 65 tasi sogʻlom ayollar boʻlib, 64 tasida esa BTDD mavjud. Tadqiqot natijalariga koʻra, BTDD mavjud homiladorlarda nazorat guruhi bilan solishtirganda qondagi oksiprolin miqdori yuqoriroq, magniy miqdori esa kamroqligi aniqlandi. Shuningdek, magniy preparatlari qabul qilish bu koʻrsatkichlar me’yorllashishiga olib kelgan. Tadqiqot xulosasi boʻyicha, BTDD mavjud homiladorlarda qondagi magniy hamda oksiprolin miqdorini aniqlash ularda homiladorlikni olib borishda muhim hisoblanadi.
IMPLIKASI CERAMAH KEAGAMAAN YOUTUBE GUS MUWAFIQ OFFICIAL TERHADAP KESADARAN CINTA TANAH AIR SANTRI PESANTREN MAHASISWA HASYIM ASY’ARI SEWON BANTUL YOGYAKARTA
Authors: Miftahul Khoir , Rifa'i Akhmad 
Published: January 2024

Penggunaan media baru sebagai sarana dakwah semakin meningkat, salah satunya adalah youtube. Perubahan media dari konvensional menjadi audio visual memberikan banyak pengaruh kepada para jamaah, salah satunya rasa cinta terhadap tanah air. Gus Muwafiq salah satu pengguna media baru dengan menggunakan channel youtube Gus Muafik Official. Ceramah yang dilakukan Gus Muwafiq dominan berisi ajakan untuk menjadi warga Negara yang baik serta memiliki kepedulian tinggi (nasionalisme) terhadap keutuhan dan kesatuan republik Indonesia. Sebagian dari santri Hasyim Asy’ari Cabean Sewon Bantul merupakan penonton tetap dari channel ini. Kebiasaan tersebut tentu akan berdampak terhadap aspek psikologis dan perilaku santri dalam kehidupan sehari-hari terkhusus pada rasa cinta air. Peneliti menggunakan dua subjek penelitian yaitu pimpinan atau pengelola Pesantren Hasyim Asy’ari dan santri yang menonton ceramah agama di youtube Gus Muafik Official. Sedangkan objek penelitian ini adalah perubahan sikap santri yang mengacu pada kesadaran cinta tanah air. Peneliti menggunakan pendekatan deskriptif kualitatif dengan proses pengumpulan data dilakukan dengan metode observasi, wawancara dan dokumentasi. Hasil penelitian menunjukan adanya dampak ceramah agama channel youtube Gus Muwafiq Official terhadap kesadaran cinta tanah air santri pesantren mahasiswa Hasyim Asy’ari. Dampak tersebut ditunjukkan dalam beberapa bentuk sikap; pertama menjunjung dan mentaati hukum dan pemerintah yang ditunjukkan dengan kepatuhan terhadap Undang-Undang serta kebijakan-kebijakan yang dikeluarkan pemerintah. Kedua, membela negara yang ditunjukkan dengan ikut serta menjaga Indonesia dari hal-hal yang mengancam keutuhan bangsa dan negara. Ketiga, menghormati hak asasi manusia yang ditunjukkan dengan kesadaran bahwa penghormatan kepada sesama manusia merupakan kebutuhan setiap manusia yang juga diatur dalam hukum negara. Penelitian ini diharapkan menjadi media pembelajaran dakwah dan komunikasi, khususnya bahwa rasa cinta tanah air yang terlihat pada sikap serta perilaku santri dipengaruhi oleh berbagai aspek yang salah satunya adalah media youtube
Kata Kunci: Youtube, Ceramah Agama, Gus Muwafiq, Cinta Tanah Air
Polatuzumab Vedotin (Polivy)
Authors: CADTH  
Published: January 2024

CADTH recommends that Polivy in combination with rituximab, cyclophosphamide, doxorubicin, and prednisone (R-CHP) not be reimbursed by public drug plans for the treatment of adult patients with previously untreated large B-cell lymphoma (LBCL), including diffuse large B-cell lymphoma (DLBCL) not otherwise specified (NOS), high-grade B-cell lymphoma, Epstein-Barr virus–positive DLBCL NOS, and T-cell/histiocyte-rich LBCL.
Evidence from a clinical trial showed that 6.6% more patients with newly diagnosed moderate- to high-risk LBCL were alive without their disease progressing 2 years after treatment with Polivy in combination with R-CHP compared to those treated with traditional chemoimmunotherapy (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone [R-CHOP]). However, there is uncertainty whether this difference observed in the clinical trial translates to a meaningful difference in the real world. The evidence from the trial did not show that Polivy combined with R-CHP prolonged survival compared to R-CHOP. It is also unknown if Polivy in combination with R-CHP would reduce disease symptoms or improve functioning compared to R-CHOP because there were no differences between the 2 groups.
Patients identified a need for treatments that prolong disease remission, prolong survival, control disease symptoms, normalize blood counts, and improve quality of life. Based on the evidence submitted, it is not clear that Polivy in combination with R-CHP would provide a meaningful benefit in prolonging remission or meet the other important needs in LBCL.
Pilanesbergite: a new rock-forming mineral occurring in nepheline syenite from the Pilanesberg Alkaline Complex, South Africa
Authors: Dal Bo Fabrice , Friis Henrik , Elburg Marlina A. , Hatert Frédéric , Andersen Tom 
Published: January 2024

Abstract. The new mineral pilanesbergite, with the ideal formula Na2Ca2Fe2Ti2(Si2O7)2O2F2, was found in a nepheline syenite, locally known as green foyaite, from the Pilanesberg Complex located in the North West Province of South Africa. Pilanesbergite occurs in green foyaite in association, and partly intergrown, with aegirine. The two minerals share an assemblage of inclusions, comprising euhedral nepheline, titanite and minor sodalite. Pilanesbergite belongs to the wöhlerite group and is isomorphic with låvenite, normandite and madeiraite. It is related to these species through the homovalent chemical substitutions Mn2+↔Fe2+ and Zr4+↔Ti4+. The empirical formula calculated on the basis of 18 anions is Na2.00(Ca1.74Na0.26)Σ2.00(Fe1.00Mn0.52Ca0.49Zr0.05)Σ2.06(Ti1.69Zr0.14Mg0.09Nb0.08)Σ2.00(Si2O7)2.00O1.84F2.16 (Z=2). The new mineral is translucent with a brown orange colour and a brownish streak. The Mohs hardness is estimated between 5 and 6 by comparison with låvenite, and no cleavage is observed. Measured and calculated densities are Dmeas=3.47 g cm−3 and Dcalc=3.40 g cm−3. In the thin section the pleochroism is strong, between straw yellow and orange red, while in immersion the strong pleochroism is observed between light yellow (α) and yellowish orange (γ). The crystals are optically biaxial (+) with α=1.743(3), β=1.768(3), γ=1.795(5) and a 2 V angle close to 90∘. The crystal structure is monoclinic (P21/a), with the unit-cell parameters a=10.7811(2), b=9.7836(1), c=7.0348(1) Å, β=108.072(2)∘ and V=705.41(2) Å3, and has been refined to R1=2.06 %. The strongest lines of the powder X-ray diffraction pattern [d, Å (I, %) (h k l)] are 3.219 (60) (310), 2.851 (100) (12-2), 2.802 (51) (320), 2.743 (27) (22-2), 2.423 (19) (40-2) and 1.723 (19) (44-2). Pilanesbergite formed under relatively reducing conditions from an agpaitic nepheline syenite magma that had evolved by fractional crystallization mainly of aegirine. Further crystallization of arfvedsonite caused an increase in oxygen fugacity and a change towards higher Mn/Mn+Fe of the magma, causing a change of mineral composition from pilanesbergite towards normandite.
Towards real-time optimal control of wind farms using large-eddy simulations
Authors: Janssens Nick , Meyers Johan 
Published: January 2024

Abstract. Large-eddy simulations (LESs) are commonly considered too slow to serve as a practical wind farm control model. Using coarser grid resolutions, this study examines the feasibility of LES for real-time, receding-horizon control to optimize the overall energy extraction in wind farms. By varying the receding-horizon parameters (i.e. the optimization horizon and control update time) and spatiotemporal resolution of the LES control models, we investigate the trade-off between computational speed and controller performance. The methodology is validated on the TotalControl Reference Wind Power Plant using a fine-grid LES model as a wind farm emulator. Analysis of the resulting power gains reveals that the performance of the controllers is primarily determined by the receding-horizon parameters, whereas the grid resolution has minor impact on the overall power extraction. By leveraging these insights, we achieve near-parity between our LES-based controller and real-time computational speed, while still maintaining competitive power gains up to 40 %.
Job Order Costing
Authors: Khaddafi Muammar , Zulyani Eva , Saputra Ahmat Hadi , Dhahir Malikud , Ajrun  , Azira Eka Nur 
Published: January 2024

Penelitian ini dilatarbelakangi oleh Job Order Costing memiliki urgensi yang signifikan, terutama bagi perusahaan yang beroperasi dalam lingkungan bisnis di mana produksi melibatkan pesanan atau proyek yang bersifat khusus.Job Order Costing adalah suatu sistem akuntansi biaya yang digunakan oleh perusahaan untuk menghitung biaya produksi secara spesifik untuk setiap pesanan atau proyek yang dihasilkan. Job Order Costing cocok untuk perusahaan yang memproduksi barang atau jasa dalam jumlah terbatas atau dengan spesifikasi yang berbeda-beda untuk setiap pesanan atau proyek. Sistem ini memberikan fleksibilitas untuk mengelola biaya secara terperinci dan memantau kinerja setiap elemen produksi secara lebih akurat. Metode penelitian yang digunakan adalah literatur riview.Data yang dikumpulkan berupa buku-buku dan artikel-artikel yang berhubungan degan Job Order Costing. Analisis dilakukan untuk mengidentifikasi konsep, manfaat, dan urgensi Job Order Costing pada perusahaan. Berdasarkan hasil dan pembahasan, maka dapat disarankan kepada pihak perusahaan melakukan penerapan metode job order costing dalam penentuan harga pokok produksinya untuk menetukan harga jual dan beban produksi yang tepat. Untuk itu disarankan pula melakukan pemisahan biaya-biaya produksi, yaitu biaya bahan baku, biaya tenaga kerja langsung, dan biaya overhead pabrik secara tepat agar dapat memisahkan keuntungan dengan jelas dan membandingkannya, serta membuatkartu biaya pesanan untuk memudahkan dalam memisahkan biaya biayaberdasarkan pesanan.