bluuebunny/crossref_metadata_2025_split huggingface dataset:
Predicting endoscopic third ventriculostomy success in pediatric shunt dysfunction: a monocentric retrospective case series of 70 consecutive children, systematic review, and meta-analysis
Authors: Guida Lelio , Grenier-Chartrand Flavie , Benichi Sandro , James Syril , Paternoster Giovanna , Bourgeois Marie , Dangouloff-Ros Volodia , Messina Antonio , Boddaert Nathalie , Puget Stéphanie , Beccaria Kevin , Blauwblomme Thomas 
Published: September 2023

OBJECTIVE
The outcome of endoscopic third ventriculostomy (ETV) in children who had previously received shunts and who were experiencing shunt dysfunction is still discussed in terms of efficacy (success rate from 40% to 80%) and safety (0%–32.5% of complications). Reported predictive factors of secondary ETV failure are age, early onset of hydrocephalus, and prematurity. The best surgical strategy in the different subgroups of patients with shunt dysfunction is still debated. Therefore, the authors aimed to identify subgroups of patients in whom shunt treatment was associated with favorable outcome of ETV, to define the role of ETV in patients with global rostral midbrain dysfunction syndrome.

METHODS
This study was a monocentric retrospective case series and a meta-analysis of children who had previously received shunts and who underwent secondary ETV for shunt dysfunction between 2012 and 2022. Clinical and MRI features were examined, along with surgical outcome, etiology of hydrocephalus, and preoperative ETV Success Score. Univariate and multivariate analyses were performed to find predictors of outcome of secondary ETV. Youden’s J index was calculated on age distribution to find an optimal age cutoff. Systematic review of the literature and a meta-analysis were performed according to the PRISMA statement.

RESULTS
Seventy consecutive patients were included. The overall success rate of secondary ETV was 63%. Primary obstructive hydrocephalus, age ≥ 36 months, and the presence of aqueductal obstruction were predictors of ETV success. Multivariate analysis found that age < 36 months, primary inflammatory hydrocephalus, and presence of fourth ventricular obstruction were associated with ETV failure. All patients with global rostral midbrain dysfunction syndrome experienced clinical and radiological improvement after ETV. The meta-analysis showed that postinflammatory etiology and age < 36 months were predictors of ETV failure.

CONCLUSIONS
ETV is safe and effective for children with obstructive hydrocephalus experiencing shunt dysfunction, notably in cases of primary obstructive hydrocephalus with aqueductal stenosis, and among children whose age was ≥ 36 months who had postinflammatory hydrocephalus.
Analisis Perhitungan Harga Pokok Produksi Dengan Menggunakan Metode Full Costing Guna Penentuan Harga Jual Pokok Karet Pada PT Sampoerna Agro, Tbk Palembang
Authors: Trinanda Aprilia , Mursalin Mursalin , Saladin Hendry 
Published: September 2023

ABSTRACT
The motivation of this study is to determine the estimated production costs by using a full costing strategy to determine the cost of goods sold elastic at PT Sampoerna Agro, Tbk Palembang. This examination is a kind of subjective illustrative investigative research. The types of information used in this exam are documentation and writing studies. The results showed that PT Sampoerna Agro, Tbk Palembang used full costing techniques in calculating production costs. The organization should include the devaluation cost of its manufacturing equipment in the production line characterization above the cost.
Keywords: Cost of Production, Full Costing Method, and Selling Price.

ABSTRAK
Motivasi penelitian ini adalah untuk mengetahui estimasi biaya produksi dengan menggunakan strategi full costing untuk menentukan harga pokok penjualan barang elastis di PT Sampoerna Agro, Tbk Palembang. Pemeriksaan ini adalah semacam penelitian investigasi ilustratif subjektif. Ragam informasi yang digunakan dalam ujian ini adalah studi dokumentasi dan penulisan. Hasil penelitian menunjukkan bahwa PT Sampoerna Agro, Tbk Palembang menggunakan teknik full costing dalam menghitung biaya produksi. Organisasi harus memasukkan biaya devaluasi peralatan pabriknya dalam karakterisasi lini produksi di atas biaya.
Kata kunci: Harga Pokok Produksi, Metode Full Costing, dan Harga Jual.
Analisis Pendapatan dan Belanja Desa di Desa Tegalrejo Kecamatan Tugumulyo Kabupaten Musirawas
Authors: Mahgfiro Ricci Dwi , Hendri Edduar , Valianti Reva Maria 
Published: September 2023

ABSTRACT
This study aims to analyze Village Income and Expenditures in Tegalrejo Village, Tugumulyo District, Musirawas Regency per year, to determine the increase and decrease in village income and expenditure and whether their management is in accordance with the principles of Village financial management, namely Participatory, Transparency and Accountability and Discipline. Budget. This research was conducted using a qualitative descriptive method and data collected through observation, interviews, and documentation. The data is in the form of an archive of reports on the realization of the Village Budget for 2019,2020, 2021, the results of the description are obtained through a comparison of Permendagri No. 113 of 2014 with facts and conditions in the Tegalrejo Village. The results of the study show that the management of Village Finance, especially Village Income and Expenditures in the Tegalrejo City Village in general, has followed the Minister of Home Affairs Regulation and the Law governing Village finances, and has implemented the principles of Village financial management, namely Participatory, Transparency and Accountability and Discipline. Budget.
Keywords: Village Income and Expenditure, Participatory, Transparent and Accountable, Budget Discipline.

ABSTRAK
Penelitian ini bertujuan untuk menganalisis Pendapatan dan Belanja Desa di Desa Tegalrejo Kecamatan Tugumulyo Kabupaten Musirawas per tahunya, untuk mengetahui peningkatan dan penurunan pendapatan dan belanja desa dan pengelolaanya apakah sudah sesuai dengan asas pengelolaan keuangan Desa yaitu Partisipatif, Transfaran dan Akuntabel serta Disiplin Anggaran. Penelitian ini dilakukan dengan menggunakan Metode deskriptif kualitatif dan data dikumpilkan melalui Observasi, wawancara, dan dokumentasi. Data berupa arsip laporan realisasi Anggaran pendapatan dan Belanja desa tahun 2019,2020,2021, hasil deskripsi didapat melalui perbandingan Permendagri No 113 Tahun 2014 dengan fakta dan Kondisi yang ada di Desa Tegalrejo. Hasil Penelitian menunjukan bahwa pengelolaan Keuangan Desa khususnya Pendapatan dan Belanja Desa di Desa Tegalrejosecara garis besar telah mengikuti Peraturan Mentri dalam Negri dan Undang-Undang yang mengatur tentang keuangan Desa, dan telah menerapkan asas pengelolaan keuangan Desa yaitu Partisipatif, Transfaran dan Akuntabel serta Disiplin Anggaran.
Kata kunci: Pendapatan dan Belanja Desa, Partisipatif, Transparan dan Akuntabel, Disiplin Anggaran.
Model Contextual Teaching and Learning Berbantuan Media Konkrit Untuk Meningkatkan Kemampuan Berpikir Kritis dan Hasil Belajar
Authors: Putri Tariza Rosita , Indarini Endang 
Published: September 2023

Latar belakang masalah pada penelitian ini adalah rendahnya kemampuan berpikir kritis dan hasil belajar siswa. Guru masih kesultan dalam menentukan strategi pembelajaran yang dapat membantu siswa meningkatkan kemampuan berpikirnya. Sehingga tingkat keaktifan siswa masih rendah di dalam proses pembelajaran tematik yang berdampak pada hasil belajar siswa belum tuntas. Contextual Teaching and Learning dapat dijadikan solusi rendahnya kemampuan berpikir kritis dan hasil belajar siswa. Penelitian ini merupakan Penelitian Tindakan Kelas yang bertujuan untuk meningkatkan kemampuan berpikir kritis dan hasil belajar peserta didik di Kelas V SD N Bringin 02. Subyek dalam penelitian ini adalah peserta didik kelas V SD Negeri Bringin 02, Kecamatan Bringin, Kabupaten Semarang tahun ajaran 2022/2023 dengan jumlah siswa sebanyak 24. Hasil penelitian ini menunjukkan penerapan model pembelajaran CTL berbantuan media konkrit dapat meningkatkan kualitas pembelajar di kelas V SD Negeri Bringin 02. Pada tindakan I ketuntasan belajar siswa adalah 46% atau 11 siswa dengan nilai rata-rata 57,20 dan nilai maksimum 84 sedangkan nilai minimum 18 melihat hasil yang belum memuaskan maka dilakukan tindakan II. Pada tindakan II ketuntasan belajar siswa mencapai 83% atau 20 siswa yang nilai rata-rata meningkat menjadi 77,83 dan nilai maksimum meningkat menjadi 100 sedangkan dan nilai minimum menjadi 48, dengan ini syarat keberhasilan penelitian 80 %. Berdasarkan hasil penelitian dapat disimpulkan bahwa penerapan model pembelajaran Contxtual Teaching and Learning berbantuan media konkrit dapat meningkatkan kemampuan berpikir kritis dan hasil belajar siswa.
Teknik Dasar Senam Lantai: Bagaimana Model Problem Based Learning Dapat Meningkatkan Sikap Lilin dan Kayang Siswa Sekolah Dasar
Authors: Zahra Hafifah , Maulana Firman , Nugraheni Wening 
Published: September 2023

Penelitian ini bertujuan untuk meningkatkan hasil pembelajaran psikomotor teknik dasar pada pembelajaran senam lantai sikap lilin dan sikap kayang melalui model pembelajaran problem based learning pada siswa kelas IV SDN Palasari Tahun ajaran 2022/2023. Penelitian ini merupakan penelitian tindakan kelas (PTK) dengan teknik pengumpulan data menggunakan instrumen tes, lembar observasi dan catatan lapangan. Penelitian ini menggunakan metode kuantitatif. Subjek dalam penelitian ini adalah siswa kelas IV yang berjumlah 30 siswa. Berdasarkan hasil penelitian bahwa peningkatan hasil pembelajaran psikomotor senam lantai sikap lilin dan sikap kayang melalui model pembelajaran problem based learning ditandai dengan peningkatan nilai rata-rata siswa. Nilai rata-rata pada kondisi awal siswa sebesar 64,99 dengan persentase ketuntasan sebesar 30,00%. Kondisi tersebut mengalami peningkatan pada siklus I yaitu sebesar 70,56 dan persentase ketuntasan sebesar 46,66%. Kemudian setelah melanjutkan ke siklus II siswa kembali mengalami peningkatan sebesar 79,16 dengan persentase ketuntasan sebesar 83,33%. Untuk materi sikap kayang kondisi awal sebesar 66,38 dengan persentase ketuntasan sebesar 33,33%. Kondisi tersebut mengalami peningkatan pada siklus I yaitu sebesar 68,05 dan persentase ketuntasan sebesar 43,33%. Kemudian setelah melanjutkan ke siklus II siswa kembali mengalami peningkatan sebesar 76,93 dengan persentase ketuntasan sebesar 86,66%.
The Advantages of Combined Regional and General Anesthesia in Ophthalmic Surgery in Children
Authors: Abdul-Sattar Rand S. , Al-Maini Ali H. 
Published: October 2023

الخلفية: التخدير الموضعي هو إجراء شائع لدى المرضى البالغين الذين يخضعون لجراحة العيون ولكن لا يمكن القيام به بمفرده في الفئة العمرية للأطفال. ويرافق التخدير العام مضاعفات أثناء الجراحة وبعد العملية الجراحية.
الهدف: تحديد ما إذا كان استخدام التخدير الموضعي مع التخدير العام في إجراءات عيون الأطفال يحسن نتائج المرضى أم لا.
الطريقة: تم شمول أربعين طفلاً تتراوح أعمارهم بين ستة أعوام واثني عشر عامًا في الدراسة التي أجريت في مستشفى غازي الحريري/ قسم العيون ومستشفى ابن الهيثم (مستشفى العيون) وكلاهما مستشفى تعليمي، في الفترة من كانون الأول 2018 إلى تشرين الأول 2019، وقسموا إلى مجموعتين: GA (التخدير العام)، و GA-R (التخدير العام - التخدير الموضعي). تم قياس معدلات ضربات القلب (HR)، متوسط ​​الضغط الشرياني (MAP)، تفاعل القلب (OCR) والغثيان والقيء بعد الجراحة (PONV). تم الحصول على جميع الموافقات المطلوبة من المجلس العراقي للتخصصات الطبية. تم إجراء التحليل الإحصائي باستخدام SPSS V26. تعتبر قيمة P <0.05 ذات أهمية إحصائية.
النتائج: لم يصب أي مريض بتفاعل عيني قلبي أو إضافات ضرورية للتخدير أثناء الجراحة في GA-R مقارنة بمجموعة GA . كانت القياسات أثناء العملية لدقات القلب ومتوسط ​​الضغط الشرياني ​​قراءة أقل في مجموعة GA، مجموعة GA-R (p <0.05). بالمقارنة مع مجموعة GA، فإن مجموعة GA-R قد قللت من حدوث الغثيان والقيء بعد الجراحة p <0.05. واحتاج عدد أكبر من المرضى في مجموعة GA إلى تسكين أكثر من مجموعة GA-R.
الإستنتاج: يعد استخدام التخدير الموضعي كحقن حول المقلة مع التخدير العام إجراءً آمنًا وناجحًا في جراحات عيون الأطفال
[Corrigendum] Note on the Riemann Hypothesis: International Conference on Recent Developments in Mathematics (ICRDM 2022)
Authors: Vega Frank 
Published: October 2023

Robin's criterion states that the Riemann hypothesis is true if and only if the inequality \(\sigma(n) < e^{\gamma} \cdot n \cdot \log \log n\) holds for all natural numbers \(n > 5040\), where \(\sigma(n)\) is the sum-of-divisors function of \(n\) and \(\gamma \approx 0.57721\) is the Euler-Mascheroni constant. We require the properties of superabundant numbers, that is to say left to right maxima of \(n \mapsto \frac{\sigma(n)}{n}\). In this note, using Robin's inequality on superabundant numbers, we prove that the Riemann hypothesis is true. This is a "Corrigendum" for a paper presentation at the ICRDM 2022 held at Canadian University Dubai, Dubai, UAE during 24-26 August 2022. Besides, this proof is an extension of the article "Robin's criterion on divisibility" published by The Ramanujan Journal on May 3rd, 2022.
Analisa Repetisi Ijin Pada Perkerasan Lentur Dengan Metode Mekanistik-Empiris (Studi Kasus : Ruas Jalan Cikkee-Lempongbangke Kabupaten Soppeng)
Authors: Purnama Haerul , Hidayat Arman 
Published: October 2023

Abstrak
Metode mekanistik empiris pada perencanaan perkerasan. mendasarkan desain pada sifat-sifat mekanis material yang berhubungan dengan input beban dan responnya terhadap pembebanan.. Nilai respon perkerasan pada metode mekanis empiris adalah nilai tegangan dan regangan yang terjadi pada tiap lapisan yang dikontrol melalui parameter kegagalan guna menentukan nilai repetisi ijin berdasarkan tingkat kerusakan deformasi. kerusakan retak alur dan retak lelah pada lapisan Perkerasan. Mendasarkan pada hal itu maka dapat dilakukan evaluasi repetisi ijin perkerasan eksisting berdasarkan nilai kekuatan mekanis material perkerasan terbangun dan beban lalu-lintas. Penelitian ini bertujuan untuk menentukan nilai repetisi ijin lapisan perkerasan dan membandingkannya dengan nilai repetisi desain. berdasarkan hasil penelitian diperoleh nilai repetisi ijin pada ruas Ruas Jalan Cikkee-Lempongbangke untuk kerusakan retak lelah sebesar 20.273.645 ESAL. Kerusakan retak alur permukaan Sebesar 839.423 ESAL dan kerusakan deformasi permanen sebesar 2.443.336 ESAL. Nilai repetisi ijin ini masih cukup untuk mengakomodasi nilai repetisi desain sebesar 800,000 ESAL.
Segmenting computed tomograms for cardiac ablation using machine learning leveraged by domain knowledge encoding
Authors: Feng Ruibin , Deb Brototo , Ganesan Prasanth , Tjong Fleur V. Y. , Rogers Albert J. , Ruipérez-Campillo Samuel , Somani Sulaiman , Clopton Paul , Baykaner Tina , Rodrigo Miguel , Zou James , Haddad Francois , Zahari Matei , Narayan Sanjiv M. 
Published: October 2023

BackgroundSegmentation of computed tomography (CT) is important for many clinical procedures including personalized cardiac ablation for the management of cardiac arrhythmias. While segmentation can be automated by machine learning (ML), it is limited by the need for large, labeled training data that may be difficult to obtain. We set out to combine ML of cardiac CT with domain knowledge, which reduces the need for large training datasets by encoding cardiac geometry, which we then tested in independent datasets and in a prospective study of atrial fibrillation (AF) ablation.MethodsWe mathematically represented atrial anatomy with simple geometric shapes and derived a model to parse cardiac structures in a small set of N = 6 digital hearts. The model, termed “virtual dissection,” was used to train ML to segment cardiac CT in N = 20 patients, then tested in independent datasets and in a prospective study.ResultsIn independent test cohorts (N = 160) from 2 Institutions with different CT scanners, atrial structures were accurately segmented with Dice scores of 96.7% in internal (IQR: 95.3%–97.7%) and 93.5% in external (IQR: 91.9%–94.7%) test data, with good agreement with experts (r = 0.99; p &lt; 0.0001). In a prospective study of 42 patients at ablation, this approach reduced segmentation time by 85% (2.3 ± 0.8 vs. 15.0 ± 6.9 min, p &lt; 0.0001), yet provided similar Dice scores to experts (93.9% (IQR: 93.0%–94.6%) vs. 94.4% (IQR: 92.8%–95.7%), p = NS).ConclusionsEncoding cardiac geometry using mathematical models greatly accelerated training of ML to segment CT, reducing the need for large training sets while retaining accuracy in independent test data. Combining ML with domain knowledge may have broad applications.
Digging for gold: evaluating the authenticity of saffron (Crocus sativus L.) via deep learning optimization
Authors: Elaraby Ahmed , Ali Hussein , Zhou Bin , Fonseca Jorge M. 
Published: September 2023

IntroductionSaffron is one of the most coveted and one of the most tainted products in the global food market. A major challenge for the saffron industry is the difficulty to distinguish between adulterated and authentic dried saffron along the supply chain. Current approaches to analyzing the intrinsic chemical compounds (crocin, picrocrocin, and safranal) are complex, costly, and time-consuming. Computer vision improvements enabled by deep learning have emerged as a potential alternative that can serve as a practical tool to distinguish the pureness of saffron.MethodsIn this study, a deep learning approach for classifying the authenticity of saffron is proposed. The focus was on detecting major distinctions that help sort out fake samples from real ones using a manually collected dataset that contains an image of the two classes (saffron and non-saffron). A deep convolutional neural model MobileNetV2 and Adaptive Momentum Estimation (Adam) optimizer were trained for this purpose.ResultsThe observed metrics of the deep learning model were: 99% accuracy, 99% recall, 97% precision, and 98% F-score, which demonstrated a very high efficiency.DiscussionA discussion is provided regarding key factors identified for obtaining positive results. This novel approach is an efficient alternative to distinguish authentic from adulterated saffron products, which may be of benefit to the saffron industry from producers to consumers and could serve to develop models for other spices.
Specific IgG glycosylation differences precede relapse in PR3-ANCA associated vasculitis patients with and without ANCA rise
Authors: Wojcik Iwona , Wuhrer Manfred , Heeringa Peter , Stegeman Coen A. , Rutgers Abraham , Falck David 
Published: September 2023

IntroductionImmunoglobulin G (IgG) contains a conserved N-glycan in the fragment crystallizable (Fc), modulating its structure and effector functions. In anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) alterations of IgG Fc-glycosylation have been observed to correlate with the disease course. Here, we examined longitudinal changes in N-linked Fc glycans of IgG in an AAV patient cohort and their relationship with disease flares.MethodsUsing liquid chromatography coupled with mass spectrometry, we analysed IgG Fc-glycosylation in 410 longitudinal samples from 96 individuals with AAV.ResultsAnalysis of the cross-sectional differences as well as longitudinal changes demonstrated that IgGs of relapsing PR3-ANCA patients have higher ΔFc-bisection at diagnosis (P = 0.004) and exhibit a decrease in Fc-sialylation prior to the relapse (P = 0.0004), discriminating them from non-relapsing patients. Most importantly, PR3-ANCA patients who experienced an ANCA rise and relapsed shortly thereafter, exhibit lower IgG Fc-fucosylation levels compared to non-relapsing patients already 9 months before relapse (P = 0.02).DiscussionOur data indicate that IgG Fc-bisection correlates with long-term treatment outcome, while lower IgG Fc-fucosylation and sialylation associate with impending relapse. Overall, our study replicated the previously published reduction in total IgG Fc-sialylation at the time of relapse, but showed additionally that its onset precedes relapse. Furthermore, our findings on IgG fucosylation and bisection are entirely new. All these IgG Fc-glycosylation features may have the potential to predict a relapse either independently or in combination with known risk factors, such as a rise in ANCA titre.
Comparison of surgical outcomes between iStent inject W implantation and microhook ab interno trabeculotomy in combination with phacoemulsification in primary open-angle glaucoma patients
Authors: Onoe Hiromitsu , Hirooka Kazuyuki , Namiguchi Koji , Mizoue Shiro , Hosokawa Hiroko , Mochizuki Hideki , Okada Naoki , Tokumo Kana , Okumichi Hideaki , Kiuchi Yoshiaki 
Published: September 2023

PurposeTo examine primary open-angle glaucoma patients after undergoing combined cataract surgery with microhook ab interno trabeculotomy (μLOT-Phaco) or iStent inject W implantation (iStent-Phaco), and then evaluate the surgical outcomes after a minimum of 6 months of follow-up.MethodsBetween October 2020 and July 2022, 39 μLOT-Phaco eyes and 55 iStent-Phaco eyes that underwent surgery were evaluated in this retrospective, multicenter comparative case series. Data that included preoperative and postoperative intraocular pressure (IOP), number of glaucoma medications, and occurrence of complications were collected from medical records and then examined. Surgical failure was defined as patients exhibiting a &lt; 20% reduction in the preoperative IOP or an IOP &gt; 18 mmHg on two consecutive follow-up visits, or when patients were required to undergo reoperation. Success rates were determined based on a Kaplan–Meier survival analysis.ResultsAt 3, 6 and 12 months postoperatively, there was a significant postoperative reduction in the IOP (p &lt; 0.001) and in the medications scores (p &lt; 0.001) for both of the groups. In the μLOT-Phaco and iStent-Phaco groups, the probabilities of success at 6 and 12 months were 55.3 and 45.5%, and 48.4 and 45.5% (p = 0.38; log-rank test), respectively. In the iStent-Phaco group, there was a significant decrease in the hyphema.ConclusionComparable surgical outcomes occurred for both the μLOT and iStent inject W procedures.
Dietary inflammatory index in relation to severe coronary artery disease in Iranian adults
Authors: Dadaei Zahra , Bagherniya Mohammad , Sadeghi Omid , Khosravi Alireza , Shirani Shahin , Askari Gholamreza 
Published: September 2023

BackgroundLimited findings are available on the relationship between dietary inflammation index (DII) and severe coronary artery disease (CAD). Considering the high prevalence of CAD and its complications, we examined the relationship between DII and CAD.MethodsThis cross-sectional study was conducted on 275 adults who underwent elective angiography. Severe coronary artery disease was measured by the gensini scoring system. DII was measured by a valid semi-quantitative 168-item food frequency questionnaire (FFQ). Blood samples were collected after 12 h of fasting to measure serum lipid profile and quantitative C-reactive protein (q-CRP) levels. Binary logistic regression was used to calculate the odds (OR) and 95% confidence interval (CI).ResultsPeople in the last tertile of the DII had a higher chance of suffering from severe coronary artery disease (OR: 3.71; 95% CI: 1.97–6.98), hypercholesterolemia (OR: 2.73; 95% CI: 5.03–1.48), reduced HDL-cholesterol levels (OR: 3.77; 95% CI: 9.34–1.52), and hypertension (OR: 1.93; 95% CI: 3.49–1.06) compared to people in the first tertile. After adjusting for confounding factors, the relationship remained significant. A direct and significant relationship was observed between the DII and increased q-CRP levels, which disappeared after adjusting for confounding factors in the adjusted model (OR: 2.02; 95% CI: 0.86–4.73).ConclusionThis cross-sectional study showed a direct and linear relationship between following an anti-inflammatory diet and decreasing the chance of severe CAD. Therefore, it seems necessary to implement community-based educational programs to promote healthy nutrition in order to prevent CADs.