bluuebunny/crossref_metadata_2025_split huggingface dataset:
RECESSION EXPERIENCES AND SELF-REPORTED DAILY SLEEP QUALITY IN MID-LIFE AND AGING ADULTS
Authors: Bhat Aarti , Lee Sun Ah , Diaz Jose , Almeida David 
Published: December 2023

Abstract
Adverse economic events can negatively impact various indicators of health, including sleep quality. Sleep quality issues are associated with chronic physical health conditions and poor mental health. While there has been a more established body of work on stress and global indicators of sleep, assessing sleep quality at the daily level can contribute to further understanding how stress can impact everyday life. Given that midlife and older adults are a fast-growing demographic in the United States, who have experienced economic events such as the 2007-2009 Great Recession as well as the COVID-19 pandemic, it becomes critical to study how such economic experiences affect markers of wellbeing, such as daily sleep, for aging adults. This study examines the effect of recession hardships on daily sleep quality in aging adults using the Midlife in the United States Refresher study. This study will combine the MIDUS Refresher Survey project with the MIDUS Refresher Biomarker project (n=863) to assess the contribution of adverse Recession events across financial, job, and housing experiences (86% of participants reported at least one adverse Recession experience) on quality of sleep (e.g., time to fall asleep, wakefulness during night) using the Daily Sleep Diary component of the MIDUS Refresher Biomarker project, in which participants self-reported on their sleep quality for seven days. This study will provide insight into how certain types of Recession events may differentially affect daily sleep patterns for aging adults; and provide information of within and between person differences in how Recession events impact daily sleep.
A SYSTEMATIC REVIEW OF ENABLERS AND BARRIERS TO CANCER SURVIVORSHIP IN NIGERIA
Authors: Nwakasi Candidus , Mahmoud Kafayat , Esiaka Darlingtina 
Published: December 2023

Abstract

Background
Nigeria is benefitting from public health and healthcare advancement which is increasing cancer care in the country. As a result, more people are surviving cancer. However, this should not mask the fact that Nigeria, a rapidly aging country which an increased risk of cancer incidence, bears a heavy health burden of about 72,000 cancer deaths per year — this underscores cancer as a leading cause of death among Nigerians. The purpose of this study was to identify and synthesize factors that are enablers or barriers to cancer survivorship in Nigeria and add to the body of knowledge on cancer survivorship in the global south. Method. Using PRISMA guidelines, we conducted a systematic review across Scopus, PubMed, and databases. Given that cancer survivorship covers periods from diagnoses, to treatment, and end of life, we identified 31 peer-reviewed studies that assessed cancer treatment, management, care, and survivorship in Nigeria.

Results
Eight themes emerged from our review of 31 peer-reviewed studies that examined factors that are enablers of barriers to cancer survivorship among Nigerians. Some of the themes include a desire to survive, the availability of treatment options, self-management, and the availability of pseudo-healthcare providers. We later grouped the themes under three categories, healthcare, economic, and psychological factors.

Conclusion
Cancer survivors in Nigeria are confronted with several issues that affect their quality of life and health outcomes. This highlights the need for studies on cancer survivorship to inform the design of tailored health improvement interventions for cancer survivors in Nigeria.
THE ROLE OF PERSON- AND FAMILY-ORIENTED LONG-TERM SERVICES AND SUPPORTS
Authors: Fabius Chanee , Okoye Safiyyah , Wu Mingche , Jopson Andrew , Burdgorf Julia , Ballreich Jeromie , Scerpella Daniel , Wolff Jennifer 
Published: December 2023

Abstract
Long-term services and supports (LTSS) in the United States are defined by its patchwork and unequal nature. Data constraints obscure our understanding of inequities in LTSS care experiences and factors that may attenuate them. We advance a conceptual framework of LTSS-relevant environmental domains. We then link measures from public use datasets to person-reported care experiences from the 2015 National Health and Aging Trends Study. We assess relationships between domains of LTSS-relevant environmental characteristics and three LTSS care experiences: 1) adverse consequences due to unmet need, 2) participation restrictions in valued activities, and 3) subjective well-being. We examine 2,411 older adults with disabilities, and key subgroups by race, dementia, and Medicaid enrollment status. We find that for the roughly 10.4 million older adults with disabilities in the community, the LTSS environment is associated with care experiences, but the direction of the relationship varies by domain. Measures of neighborhood social and economic deprivation (e.g., poverty, social cohesion) are associated with experiencing adverse consequences due to unmet needs. Measures of the health care and social services delivery environment (e.g., Medicaid Home and Community-Based Service Generosity, average direct care worker wage, paid family leave) are inversely associated with experiencing participation restrictions. Select measures of the built and natural environment (e.g., housing affordability) are associated with participation restrictions and low subjective well-being. Relationships between measures of LTSS-relevant environmental characteristics and care experiences generally held in directionality but were attenuated for key subpopulations. Results reinforce the importance of strengthening environmental policies that support aging in place.
CHILDHOOD FAMILY ENVIRONMENT, GENETIC RISK FOR ALZHEIMER’S DISEASE, AND LATE-LIFE COGNITIVE DECLINE
Authors: Zhang Shiyang , Han Sae Hwang 
Published: December 2023

Abstract
How genetic risks for Alzheimer’s disease (AD) interact with environmental factors to shape individuals’ cognitive trajectories across the lifespan is a burgeoning area of research. However, relatively little is known about the role childhood family environment plays in the relationship between genetic risk factors for AD and cognitive decline in later life. This study examined whether and how early-life family environments may modify cognitive decline associated with genetic AD risks. Using longitudinal data from the Health and Retirement Study (HRS; 1998-2018), we followed over 9,000 individuals aged 51 and older during the observation period spanning nearly two decades. Cognitive functioning was assessed with the full cognitive battery from the HRS. Childhood family environment was evaluated separately with the relationship quality with one’s mother and the number of household adults before the age of 16. We estimated a series of multilevel models to assess the association between polygenic risk score for AD (PGS-AD) and changes in cognitive functioning, and whether the association was moderated by the two measures of childhood social capital. Findings indicated that childhood maternal relationship quality, but not the number of household adults, protected against cognitive decline accelerated by PGS-AD. That is, the associations between higher PGS-AD and accelerated cognitive decline were attenuated for individuals who reported a better childhood maternal relationship. Findings are in line with the biopsychosocial model of health and suggest that a better quality of maternal relationships in childhood may have a protective effect on cognitive functioning across the lifespan.
COVARIATE-ADJUSTED ASSOCIATIONS OF COGNITION, DEPRESSIVE SYMPTOMS, AND SOCIAL SUPPORT WITH LIFE SPACE MOBILITY
Authors: Armah Henrietta , Clay Olivio 
Published: December 2023

Abstract
Diabetes mellitus is one of the most common chronic diseases among older adults and can affect their movement, participation, and all aspects of daily living, thus restricting life space mobility. Life space mobility reflects individuals’ ability to move independently and engage in social activities. This study examines covariate-adjusted associations of cognition, depressive symptoms, amount of support received and satisfaction with support with life space mobility. The study included 247 older adults aged 65 and above from the University of Alabama at Birmingham (UAB) Diabetes and Aging Study of Health (DASH). Average age was 73, 45% of the sample were Black/African American, 53% were female, and 47% were married. Results from multiple covariate-adjusted regression analyses revealed that being Black/African American, older, female, and higher depressive symptoms significantly predicted lower life space mobility (all p’s &lt; .05) while being married, educated, and reporting better health significantly predicted greater life space mobility. Similarly, higher cognitive function was a significant predictor of greater life space mobility (B = .140, p &lt; .05). Results remained significant even when adjusted for covariates. Amount of support received and satisfaction with support did not predict life space mobility. Findings from this investigation identify individuals who are at risk for restricted life space mobility and suggest protective factors. Establishing these associations with life space mobility within a health disparities framework would be important as it would draw attention to functioning in later life for socially disadvantaged groups and help inform interventions.
SOCIAL CONNECTIONS AND SUICIDE DESIRE AMONG COMMUNITY-DWELLING OLDER ADULTS
Authors: Mize Mary Chase 
Published: December 2023

Abstract
As the population of older adults in the U.S. continues to increase, so will the prevalence of critical mental health concerns such as suicide (CDC, 2020). The Interpersonal Theory of Suicide posits desire for suicide develops from the simultaneous presence of thwarted belongingness and perceived burdensomeness (Joiner, 2005). Low social connection and perceptions of low social support can result in feelings of thwarted belongingness and perceived burdensomeness among older adults (Van Orden et al., 2012). The purpose of this study was to understand the relationship between social connections (frequency of contact with others, both synchronous or “real-time” and/or asynchronous) and suicide desire among community-dwelling older adults who received home-delivered meals (HDM) during Covid-19. This cross-sectional study was part of a grant-funded project by the Administration for Community Living. Among a sample of 320 older adults in a large southeast metropolitan area, we identified 25 participants who had no social connections of any type within the past week. These individuals had the highest levels of suicide desire and loneliness, and had the lowest levels of perceived social support. Implications for practice and future research include: a) recognition of the social connections HDM volunteers provide to older adults who may be lonely and at risk of suicide, b) an understanding of suicide desire among older adults during the Covid-19 pandemic, and c) opportunities for nutrition service providers to invest in equipping HDM volunteers to respond to suicide.
SOCIAL NETWORK BARRIERS AND FACILITATORS TO RHEUMATOID ARTHRITIS MANAGEMENT IN HISPANIC/LATINX FAMILIES
Authors: Wilson Kamryn , Dalpe Sara , Waldman Zoe , Koehly Laura , Lin Jielu 
Published: December 2023

Abstract
Compared to their non-Hispanic White counterparts, individuals of Hispanic/Latinx heritage are more likely to develop disabilities from comorbidity and remain disabled for longer periods over the life course. Among chronic conditions, rheumatoid arthritis (RA) is very common, affecting at least 1% of the U.S. population. Evidence suggests that RA is more active and severe among Hispanic/Latinx individuals, characterized by more flare-ups, greater inflammation, higher tender/swollen joint counts, and more self-reported pain, due in part to their underuse of health services, delay in initiating treatment, and difficulty in adhering to treatment plan. In this study, we sought to identify social network factors relevant to managing RA pain and RA-attributable functional limitations, in a sample of Hispanic/Latinx families residing in the Washington DC region. We analyzed network structure and patterns of interpersonal health communication and assessed how these factors may facilitate or impede proactive healthcare, independent of individual and system-level barriers. The findings are three-fold: First, there is substantial heterogeneity in social network structure in the families examined, likely due to different immigration experiences. Second, severely contracted personal networks (e.g., isolate or singe-edge) were observed among older, foreign-born individuals who spoke Spanish and had less schooling. This was a major barrier to RA management. Finally, more health communication, closeness, and advice-seeking ties in one’s personal network facilitated use of health services which was positively correlated with health outcomes. We discuss the implications of the findings in the context of developing family network-based health education interventions.
FINANCIAL DIFFICULTY, HEALTH BEHAVIORS, AND MENTAL HEALTH OF FAMILY CAREGIVERS DURING THE COVID-19 PANDEMIC
Authors: Liu Yujun , Hughes M Courtney , Wang Heng 
Published: December 2023

Abstract
The COVID-19 pandemic greatly burdened family caregivers in the United States and across the globe as they and their family members often suffered from the COVID-19 virus and its societal implications, like social isolation and a shift to remote healthcare. This study examines the impact of the COVID-19 pandemic on financial difficulty, health behavior, and mental health outcomes among family caregivers for older adults across the intersectionality of gender and race. Using the 2020 National Health and Aging Trends Study (NHATS) COVID-19 supplement for Family Members and Friends, our sample included adult family or friend caregivers of Medicare beneficiaries aged 65 or older in the US (N = 2,062). We modeled the interrelationships between financial difficulty, health behaviors, and mental health outcomes using a structural equation model. The results indicate that within the intersectionality framework, during the pandemic, female caregivers reported less vigorous activity, more changes in walking and sleeping patterns, and more eating and watching TV than before the pandemic compared to male counterparts. Compared to white caregivers, during the pandemic, non-white caregivers showed less vigorous activity and more changes in walking, sleeping, I eating, and TV watching patterns than before the pandemic. Financial difficulty was significantly and positively associated with negative mental health. Active behavior was significantly and negatively associated with negative mental health. Health professionals should consider the interrelationships between sociodemographic factors, physical activity levels, and financial difficulties that have come to light during the pandemic when designing future programs and policies to improve family caregiver health.
PREDICTORS OF DEPRESSION IN KOREAN OLDER ADULT SPOUSAL CAREGIVERS: 2017 NATIONAL SURVEY OF OLDER KOREANS
Authors: Yun Stacy , Qualls Sara 
Published: December 2023

Abstract
Based on the sociocultural stress coping model (Knight & Sayegh, 2010), this study was aimed at examine how factors such as familism, caregiver burden, social support, and coping strategies impact Korean older adult spousal caregivers’ depression. 369 caregiver (aged 69 to 96; M = 80.68) and care recipient (aged 69 to 102; M = 81.86) spouse dyads from the 2017 National Survey of Older Koreans was used for analysis. The model demonstrated excellent model fit indices, χ2(15) = 16.29, p = .36, model χ2 to df ratio = 1.09, TLI = .99, CFI = .99, RMSEA = .02 (95% CI: .00 to .05), and SRMR = .02. Higher levels of depression was significantly predicted by lower perceived social support, β = -.30, Z = -6.35, p &lt; .001, being older, β = .16, Z = 3.12, p = .002, less education, β = -.18, Z = -3.81, p &lt; .001, and having fewer living family members, β= -.12, Z = -2.29, p = .02. Additionally, the relationship between caregiver burden and depression was fully mediated by perceived social support (β = .05, t = 3.23; 95% CI: .02 to .09). Results suggest that perceived social support is a salient factor related to depression experienced by older spousal caregivers in Korea. Findings imply the need for clinicians to devise creative interventions to increase caregiver’s sense of social support, particularly those who may reside in rural areas of Korea who are primarily older, received less education, and have fewer living family members.
GWAS OF BRAIN ENDOPHENOTYPES: ASSOCIATION OF AUTOPSY-BASED LEWY BODY COUNTS WITH MOVEMENT DISORDER RISK LOCI
Authors: Edland Steven , Hernandez Fernanado , Nasamran Chanond , Fisch Kathleen , White Lon 
Published: December 2023

Abstract
We performed a genome wide association study (GWAS) of neocortical Lewy body density. Case material were 308 autopsies of Japanese-American men (mean age at death 87.5 years; 11% with mild, and 30% with severe cognitive impairment prior to death). Lewy bodies were assessed by manual count of alpha-synuclein stained neocortical sections from the frontal, temporal, parietal, and occipital lobes. Genetic association was tested by linear models controlling for age at death assuming an additive genotypic effect. Top hits include a locus on chromosome 1q32 previously associated with amyotrophic lateral sclerosis (p=5.8e-8), intronic variants on the dopaminergic neuron axonal guidance gene EPHB1 previously associated with Parkinson’s disease (PD) (p=8.4e-6), and a locus containing two independent intron 1 variants on CSMD1, a known risk factor for autosomal dominant PD (p=1.5e-6). Complement inhibitor protein CSMD1 is a type 1 transmembrane cell adhesion molecule implicated in axonal guidance and the development, maintenance, and pruning of synapses in the adult brain. Intermediate hits include genes encoding cell adhesion molecules and a second complement inhibitor implicated in the regulation of synapses (TRAPPC9). This converging evidence points to cell adhesion proteins and complement mediated synaptic regulation in the etiology of Lewy body lesions.
AN OUTBREAK OF COVID-19 INFECTION WITH NO MORTALITY IN A GERIATRIC INSTITUTION IN COLOMBIA
Authors: Reyes-Ortiz Carlos , Ocampo-Chaparro Jose 
Published: December 2023

Abstract
Unusually, an outbreak of Covid-19 during the first year of the pandemic in an underserved geriatric institution had no mortality. This cross-sectional study aimed to determine factors associated with COVID-19 infection among 252 institutionalized older adults in Cali, Colombia’s larger geriatric hospital and nursing home, Geriatric Hospital and Nursing Home San Miguel assisting multiethnic, impoverished, and low-educated residents. This population had a median age of 80 years (range 55 to 103) and a median Barthel of 90.0; 50% were women, 19% had dementia, and 2% were obese. 84 (33.3%) were infected, and none died and did not go to the UCI or were referred to a higher-level hospital. In a multivariate logistic regression model, being infected was associated with age 80 and older, a lower Barthel score, and malnutrition. Due to collinearity, separated models showed an association between infection and higher scores on the clinical frailty scale or lower grip strength. All institutionalized older adults with Covid-19 infection in this geriatric institution survived. It was likely related to appropriate general medical and nursing management, including well-controlled comorbidities, and individualized interdisciplinary rehabilitation, attention, and support.
A CONSULTANT PHARMACIST INTERVENTION TO DEPRESCRIBE OPIOIDS AND BENZODIAZEPINES FOR OLDER ADULTS IN PRIMARY CARE
Authors: Niznik Joshua , Busby-Whitehead Jan , Armistead Lori , Urick Benjamin , Zhao Liang , Ferreri Stefanie 
Published: December 2023

Abstract
Long-term use of opioids and benzodiazepines (BZDs) by older adults may cause harm. We evaluated the impact of a targeted consultant pharmacist opioid and BZD deprescribing intervention for older adults. We conducted a pragmatic study in which fifteen primary care clinics were randomized to receive standard care (n=7) or a consultant pharmacist service (n=8) to provide targeted medication review and recommendations for deprescribing opioids and BZDs. The primary outcome was opioid and BZD prescribing in the following year, using average daily morphine milligram equivalents (MMEs) and diazepam milligram equivalents (DMEs). We used generalized linear models to evaluate the association of the intervention with average daily MMEs and DMEs, adjusted for medication exposures in the prior year and demographics. Incident falls were examined as a secondary outcome. We included 961 opioid and 1107 BZD users, with 15.6% and 13.6% being prescribed both medications, respectively. Average daily MMEs and DMEs prescribed at baseline were 23.6 and 7.67. Deprescribing recommendations were made for 71% of opioid and BZD users seen in intervention clinics. We observed non-statistically significant reductions in average daily MMEs (Intervention: -2.42 MMEs, Control: -1.02 MMEs, p=0.71) and DMEs (Intervention: -1.0 DMEs, Control: -0.1 DMEs, p=0.06). There was no significant reduction in incident falls. A consultant pharmacist-driven intervention is a feasible approach to deliver targeted deprescribing recommendations, but did not significantly impact medication use or falls. Future studies should explore whether multimodal interventions would be more effective in achieving deprescribing and reducing medication-related harms.
STRATEGIES USED TO HELP OLDER ADULTS ACCESS VIDEO VISITS DURING COVID-19: A SYSTEMATIC REVIEW
Authors: Haller Landon , Rodriguez Rena , Park Lindsay (Na Yeon) , Lam Kenneth 
Published: December 2023

Abstract
Many articles have described how older adults struggled to access telemedicine during the COVID-19 pandemic, but few have described how that digital divide was bridged. To comprehensively describe strategies used to help older adults access telemedicine during the pandemic, we conducted a systematic review of 4 databases (PubMed, EMBASE, CINAHL, and PsycInfo) for English articles (search terms: “tele*”, “mHealth”, “eHealth”, “video*”, “65 and older”) published from March 2020 to July 2022. We included articles that described any effort to help older persons (or a predominantly older population) access synchronous video visits during the pandemic, without requirements for study design. We categorized strategies as micro-, meso-, or macro-level per the Ecological Systems Theory framework to differentiate strategies implemented by clinicians, health systems, and policymakers. From 3799 records, we included 134 articles published in 2020 (23%), 2021 (51%), and 2022 (26%); most (57%) described strategies from the US. The most common specialties were Geriatrics (24%), Other (i.e. Occupational Therapy; 18%), and Medical Subspecialties (i.e. Cardiology, Oncology; 11%). Macro-level interventions included waivers for privacy regulations and increased reimbursement for telemedicine. Meso-level interventions included mobile vans offering devices and internet connection and protocols to test visits in advance. Micro-level interventions included written signs to troubleshoot sound and adapting clinical examinations virtually. We found many interventions at different levels of society to help older adults access video visits during the pandemic. Appraisals of the feasibility of telemedicine in older persons should consider the extent to which these strategies are used.