bluuebunny/crossref_metadata_2025_split huggingface dataset:
One-Year Outcomes in Patients Who Survived COVID-19-Related Acute Respiratory Distress Syndrome (ARDS): Pulmonary Function Tests (PFTs), Oxygen Requirement, and Quality of Life (QoL)
Authors: Arfoosh Rami , Nisbet Rachel , Nguyen Kimtuyen , Herrera Martin , Kim Nathanial , Abiodoye Oluseyi , Jones Louise 
Published: October 2023

Abstract
Background: The COVID-19 pandemic saw ARDS, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), emerge as a predominant factor in patient mortality and morbidity. This study sought to gauge the first-year outcomes of survivors of COVID-19-induced ARDS in terms of pulmonary function, liberation from oxygen and QoL.Methods: We retrospectively screened 492 patients and analyzed 29 patients from our pulmonary clinic who had post-COVID-19 ARDS. We assessed data points around the 3, 6, and 12-month marks, specifically focusing on pulmonary function, oxygen requirement and QoL using the 36-Item Short Form Survey (SF 36) questionnaire.Results: Our cohort predominantly consisted of middle-aged males, with none having required invasive mechanical ventilation during their hospitalization. By the 3-month mark, a significant portion displayed reduced diffusion and restrictive patterns, with an ongoing oxygen requirement. Notably, all PFT parameters - diffusion, Forced Vital Capacity (FVC), and Forced Expiratory Volume in 1 second (FEV1) - registered improvement over the course of a year, with most of these enhancements becoming evident by the 6-month period. Both FEV1 and FVC approached normative values by the year's end. Diffusion capacity, despite marked enhancement, remained slightly abnormal at the 12-month evaluation. The proportion of patients on supplemental oxygen also dwindled considerably from 3 to 12 months, with significant reductions already observable at 6 months. Interestingly, while the SF 36 assessment for QoL did not evince consistent improvements across the board, social functioning was an exception, improving over the one-year span. The study began with participants holding an average SF 36 general health score of 63, compared to the population norm of 72.Discussion: Survivors of COVID-19 ARDS, who didn't necessitate invasive mechanical ventilation, demonstrated significant lung function recovery and a decreasing dependence on oxygen supplementation over a year's duration. However, the SF 36 QoL scores remained relatively static, potentially indicating the impact of non-pulmonary factors on QoL.
Shaping the Professional Behaviour of Junior Physiotherapists by their Communication Style. Implications on the recovery process of patients
Authors: Urea Ionela Roxana 
Published: October 2023

Abstract
Purpose: This study approaches a penetration into the basic or derived processes connected with the wish to analyse, among young physiotherapists, how communication style shapes professional behaviour for enhancing their professional style for efficiently dealing with patients during the therapeutic process.
In our study, we had 135 Romanian junior physiotherapists as participants. We used: a) Questionnaire SC (Analysis of Communication Style) adapted by the researcher in 2017 for physiotherapists (index fidelity =. 765, test-retest index= .749); b) Questionnaire of psychotherapists' professional behaviour’ features created by the researcher in 2018 (index fidelity =. 775, test-retest index= .739).
Results: The communication style manages the junior physiotherapists' professional behaviour during the therapeutic relationship with the patient and his family and the professional climate. It has several implications and several effects on current activities.
Reconstructing the Phylogeny of Calliandra sect. Androcallis (Fabaceae): Insights from the Inclusion of Colombian Species, with a Focus on the Enigmatic Taxon Calliandra medellinensis
Authors: Arias Tatiana , Saldarriaga Juan David , Arenas-Castro Henry , Idarraga-Piedrahita Alvaro , Lopez-Alvarez Norberto , Luque Eduardo Tovar , Torres-Morales German , Gonzalez Mailyn A , Soto-Calderon Ivan Dario 
Published: October 2023

Abstract

Phylogenetic relationships for the genus Calliandra section Androcallis (Fabaceae) were reconstructed, including previously sequenced species from Central and South America and unexamined species from Colombia, one of Calliandra main diversity centers. Here, we generated novel DNA sequences of Calliandra species from Colombia for the nuclear Internal Transcribed Spacer (ITS) and the chloroplast trnL and trnL-F intergenic spacer. By incorporating a broader taxonomic sampling, the relationships among main clades in Androcallis were clarified, providing a systematics framework in which to test evolutionary hypotheses. Phylogenetic analysis recovered five well-supported clades within Androcallis. Most species within each clade had similar geographical distributions and relationships between the five major clades are strongly supported for the first time. However, core Androcallis relationships, including most species from Colombia sequenced here, remain unclear. A second goal of this study was to determine the taxonomic status of Calliandra medellinensis. This enigmatic taxon emblematic of Medellín, Colombia, is found in limited numbers within the Aburrá Valley and has been proposed to be a hybrid taxon. Here, C. medellinensis, C. magdalenae and C. haematocephala were not monophyletic within the core Androcallis clade. This suggests that C. medellinensis could potentially be an interspecific hybrid between C. magdalenae and C. haematocephala, thus challenging the taxonomic status of this species; however, more informative molecular markers should be used in future studies. Specifically, genomic studies should assess interspecific hybridization demographic models. Such insights can illuminate the C. medellinensis origin, guiding conservation strategies and providing valuable evolutionary overviews.
Insecticidal effects of substances from cinnamon bark – eugenol, trans-cinnamaldehyde and cinnamaldehyde to yellow mealworm
Authors: Dzięgelewska Aleksandra , Lubawy Jan , Adamski Zbigniew 
Published: October 2023

Abstract

The use of synthetic pesticides is limited due to increasing environmental pollution and developing pest resistance, as well as the increasingly confirmed negative impact of these compounds on human health. At the same time, the demand for food grown in the spirit of organic farming is increasing. Therefore, as part of Integrated Plant Protection (IPM), biopesticides are used, i.e., substances of natural origin that are characterized by low toxicity to non-target species and easy availability. Such substances include, among others, compounds found in the bark of the Ceylon cinnamon tree (Cinnamomum verum J.Presl), such as eugenol, trans-cinnamaldehyde and cinnamaldehyde. However, the mechanism of their action has not been sufficiently researched. Therefore, this study presents the results of the impact of these compounds on the important pest of cereal crops and food stores, and - at the same time - a model organism - Tenebrio molitor beetle. The tested compounds were administered by injection, inhalation, with food or one of two contact routes: by immersing the tested larvae or by contacting them with substratum soaked in an appropriate solution of the tested compound. The results allowed us to determine the LT50 parameter, and the probit analysis carried out the LC20/30/50/95 values. The obtained results also allowed to conclude that the most effective route of administering cinnamon bark compounds is contact and injection, and the most effective is eugenol. The impact of the tested compounds on the morphological malformations of T. molitor larvae was also documented and discussed.
Higher Fluid and Lower Caloric Intakes: Associated Risk of Severe Bronchopulmonary Dysplasia in ELBW Infants
Authors: Stonestreet Barbara , Kolitz Danielle , Przystac Lynn , Tucker Richard , Oh William 
Published: October 2023

Abstract
Objective
To examine nutritional intake profiles and growth trajectories of extremely low birth weight (ELBW) infants who develop severe bronchopulmonary dysplasia (BPD).
Study Design
Case-control study using multiple logistic regression analysis with generalized estimating equations (GEE) to adjust for matching.
Results
Cumulative and mean fluid intakes were higher (p=0.003) and caloric intakes lower (p<.0001)through week two in infants who developed severe BPD (n=120) versus those without severe BPD (n=104). Mean caloric intake through week 12 was lower in infants who developed severe BPD (102±10.1 vs. 107±8.5 kcal/kg/day, p<0.0001). In logistic regression models, lower mean caloric intake through week 12 was associated with increased risk of developing severe BPD. Linear growth reduced the odds of BPD by ~30% for each Z-score point.
Conclusions
Higher fluid and lower total caloric intakes and reductions in linear growth were independently associated with an increased risk of developing severe BPD in ELBW infants.
Hybrid Off-Grid Energy Systems Optimal Sizing with Integrated Hydrogen Storage Based on Deterministic Balance Approach
Authors: Selim Alaa , El-shimy Mohamed , Amer Ghada , Ihoume Ilham , Masrur Hasan , Guerrero Josep M. 
Published: October 2023

Abstract
Incorporating diverse renewable energy sources is imperative for establishing a resilient and sustainable power infrastructure. This research explores the optimal techno-economical hybrid energy system configuration, emphasizing hydrogen energy for system balance. We introduce a novel DBM (Deterministic Balanced Method) to ascertain the annual energy output over the project’s lifespan, contrasting it with HOMER software results. Validation against HOMER Pro revealed a high consistency in our method, with differences within a 5% range. This indicates our approach’s reliability in determining hybrid energy system sizes accurately. In addition to harnessing solar radiation and wind data from NASA and METEONORM, our study encompasses a real-case evaluation of Cairo International Airport’s hybrid renewable energy systems. The system design is based on actual, researched loads. Our results not only offer insights into effective hybrid energy system sizing but also propose using surplus energy in distributed networks for industrial and transportation energy conversion applications.
The influence of deep oscillation on early physiotherapy results and inflammatory markers in patients after reconstruction of the anterior cruciate ligament of the knee joint
Authors: Oestervemb Katarzyna , Szczygieł Elżbieta , Kita Bartłomiej , Szczygielska-Babiuch Anna 
Published: October 2023

Abstract
Introduction: ACL anterior cruciate ligament rupture is one of the most common effects of sports knee injuries. Arthroscopic treatment is the least invasive type of surgery that restores the normal function of the ligament and the kinematics of the knee joint. Early introduced physiotherapy is the last stage of this treatment, which allows you to quickly regain mobility.
Aim of the study: To evaluate the influence of deep oscillation on the early results of physiotherapy and on the activity of selected indicators of vascular inflammation and embolism in patients after reconstruction of the anterior cruciate ligament of the knee joint.
Methods: The study involved 60 patients divided into 2 groups: study (N = 30) and control (N = 30). In the study group (GB), the knee joint was additionally deeply oscillated. The mean age of the examined people was 32.7±6.5 years. Women constituted 26.6% of the respondents, and men 73.3%. Measurements of the pain level (VAS scale and algeimeter), the range of motion of the knee joint, the extent of the swelling as well as the level of inflammatory and thrombotic markers (CPR and D-dimmers) were performed.
Effect of Chewing Gum in reducing Postoperative Ileus after Gastro-duodenal perforation peritonitis surgery: a prospective randomized controlled trial
Authors: MUWEL SANJAY , Suryawanshi Seema , Damde Hari Krishna , Mishra Arpan , Yadav Sanjay Kumar , Sharma Dhananjaya 
Published: October 2023

Abstract
Chewing gum reduces the duration of post operative ileus and early recovery of bowel function following elective abdominal surgery. However, its role has not been studied in cases of gastroduodenal perforation peritonitis; prompting us to conduct this study. Eighty-two patients were randomized into two groups, 39 patients received chewing gum (study group) and 43 patients were in control group. Sensation of hunger, appearance of first bowel sound, passages of flatus and faeces were significantly early in the study group; their hospital stay was also shorter. Chewing gum reduces the duration of post operative ileus in cases of gastroduodenal perforation peritonitis.
Registration number: IEC/2020-23/3359 dated 13-12-2020, Institutional Ethics committee Netaji Subhash Chandra Bose Medical College, Jabalpur, India.
Early Oral Feeding versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair: A Randomized Controlled Trail
Authors: Elshwadfy Mohammed , tobar wael , saqr ahmed , ragab amr , Salah ahmed Mohammed 
Published: October 2023

Abstract
Purpose : the study aim was comparing the benefits of postoperative early versus delayed oral feeding in duodenal ulcer repairs.
Materials and methods
Thy study was a single-center prospective, randomized, controlled trial from January to September 2023 at the Emergency department. The eligibility of patients with suspected perforated peptic ulcers was evaluated.
The patients were divided at random into two groups. the early feeding group patients were permitted to consume an oral diet six hours after surgery. Patients were given a liquid diet after 72 hours in the traditional group. Our primary outcome was hospital stay duration, and our secondary outcomes were recovery parameters and 30-day morbidities. The results were analyzed using version 21 of SPSS.
The Results
Forty-nine patients were included in the early feeding group, while 51 were in the traditional group. Patients in the early group had significantly earlier bowel sound (18.673 7; p 0.001), bowel motion (30.8 12; p = 0.001), fluid diet (14 7; p 0.001), and solid diet (35 17; p 0.001).
LOH was significantly shorter in the early feeding group (3.6 0.6 days; p 0.001(
There was a significant decrease in postoperative morbidity, including superficial SSI (p = 0.002), deep SSI (p 0.02), and pulmonary complications (p 0.0001), in the early versus delayed feeding group. However, there was insignificant difference in leak rates (0/49 vs. 1/51)
Conclusions
Early feeding can be administered safely after duodenal perforation repair. Additionally, it can improve outcomes.
The research was recorded at ClinicalTrials.gov Identifier: NCT06042933.
NK-derived exosome miR-1249-3p inhibits Mycobacterium tuberculosis survival in macrophages by targeting SKOR1
Authors: Ma Fengqian , Wang Xuan , Qiu Zhanghua , Ding Shoupeng , Du Wenya , Dai Yumei , Ma Tao , Yue Linzhi , Wang Guofu , Wang Tao , Geng Ling , Wu Lixian 
Published: October 2023

Abstract
Murine Natural Killer cells were cultivated in vitro to isolate NK-derived exosomes. Subsequent quantification via qPCR confirmed enrichment of miR-1249-3p. Ana-1 murine macrophages were cultured in vitro and subsequently inoculated with Mycobacterium tuberculosis (MTB) strain H37Rv. NK-exo and NK-exo miR-1249-3p were separately applied to the infection model, followed by immunological assays conducted post-48-hour co-culture. Western blot analyses corroborated that NK-exo exhibited exosomal marker proteins Granzyme A (GzmA), Granzyme B (GzmB), and Perforin (PFN), alongside a notable enrichment of miR-1249-3p. Functionally, NK-exo augmented the expression levels of Caspase-9,-8, and − 3, as well as PARP, while attenuating the expression of NLRP3, ASC, and Cleaved-Caspase-1. Furthermore, qPCR demonstrated an up-regulation of Caspase-9, -8, and − 3, along with pro-apoptotic factors Bax and Bid, and a concomitant down-regulation of the anti-apoptotic factor Bcl-2. The expression levels of inflammatory markers ASC, NLRP3, Cleaved-Caspase-1, and IL-1β were concomitantly decreased. ELISA findings indicated diminished levels of TNF-α and ROS secretion. NK-exo miR-1249-3p specifically targeted and attenuated the expression of SKOR-1, engendering up-regulation of apoptosis-associated proteins and down-regulation of inflammation-related proteins, consequently affecting cellular fate.Our empirical evidence substantiates that NK-exo induces macrophage apoptosis, thereby mitigating MTB survival. Furthermore, NK-exo miR-1249-3p directly targets and inhibits SKOR-1 expression, leading to macrophage apoptosis and consequently hampering the proliferation of MTB. The data implicate the potential therapeutic relevance of NK-exo and miR-1249-3p in managing drug-resistant tuberculosis.
Sentiment Analysis on Code-Mixed Tamil-English Corpus: A Comprehensive Study of Transformer-Based Models
Authors: Sangeetha M. , Nimala K. 
Published: October 2023

Abstract
NLP, or natural language processing, is a subfield of AI that aims to equip computers with the ability to understand and analyze human language. Sentiment analysis is a widely used application of NLP, particularly for examining attitudes expressed in online conversations. Nevertheless, many social media comments are written in languages that are not native to the authors, making sentiment analysis more difficult, especially for languages with limited resources, such as Tamil. To tackle this issue, a code-mixed and sentiment-annotated corpus in Tamil and English was created. This article will explain how the corpus was established, including the process of data collection and the assignment of polarities. The article will also explore the agreement between annotators and the results of sentiment analysis performed on the corpus. This work signifies various performance metrics such as precision, recall, support, and F1-score for the transformer-based model such as BERT, RoBerta, and XLM-RoBerta. Among the various models, XLM-Robert shows slightly significant positive results on the code-mixed corpus when compared to the state of art models.
Solar Radiometric Observations and Ionospheric Kinships by Space Overseer(s) at Limb-beaming Landau
Authors: Soomro Riaz A. , Sun Liguo , Ntawangaheza Jean de Dieu , Ali Sajjad , KHUHAWAR Faheem , Ali Waqas 
Published: October 2023

Abstract
Strong varying intensity of solar activities impact near-earth space environments, magnetosphere, ionosphere, thermosphere as well as on the technological systems such as satellite communications, aircraft avionics, electrical power grids, and threats to human lives. Hence, it is essential to measure the phase of solar quietness as well as to monitor total flux using radiometric devices. This paper presents an analysis of Solar Flux and Sudden Ionospheric Disturbances (SID). Additionally, the paper further analyzes three magnetic storms that occurred during a 27-day Bartels period with 3-hour interval indices. These storms include E1 on March 31, 2001, which had a geomagnetically disturbed Kp of 9, and two magnetic storms with Kp ≥ 6 (E2 on April 8, 2001, and E3 on April 11, 2001). The events of 11 days of Solar Flux were observed in April 2001, within the frequency range of (245,15400) MHz with a peak of 143,671 SFU, under the supervision of the National Oceanic and Atmospheric Administration (NOAA). On March 25, 2008, NOAA's active region (AR) 10989 experienced peepholes due to a Coronal Mass Ejection (CME) of the M1.7 class flare. This event was reported chronologically to have a widespread index/imp rating of 5/2.
Study on the mechanism of action of traditional Chinese medicine compound Wu Mei Pill in inhibiting rheumatoid arthritis through TLR4-NF-κB pathway
Authors: Fu Yuheng , Gao Chunyu , Teng Hongbo , Sun Xialin , Zhao Yaru , Zhang Wenxin , Li Siwen , Huang Liang , Fan Bowen , Zhao Yan , Zhang Haibo 
Published: October 2023

Abstract
Background
Wu Mei Pills (WMP) is a traditional Chinese medicine compound with good anti-inflammatory effects. It is used in Chinese medicine theory to treat diseases such as wind, cold. Rheumatoid arthritis (RA) belongs to the “Bi” syndrome caused by wind and cold in traditional Chinese medicine. WMP has been documented for treating RA, but its mechanism of action on RA is still unclear.
Aim of the study
This experiment mainly explores the mechanism of WMP on collagen-induced rheumatoid arthritis model in rats (CIA rat), as well as the mechanism of inflammation, migration and invasion of fibroblasts like synovial cells (RA-FLS).
Materials and methods
Analyze the chemical composition of WMP through UPLC-MS. Then, the intrinsic mechanism of WMP was analyzed by ELISA, cell scratch, Transwell, and Western blotting. Finally, WMP was applied to CIA rats to further explore the mechanism of WMP inhibiting RA.
Result
The UPLC-MS results indicate that WMP contains 181 compounds. Serum containing WMP (2%, 8%) plays an important role in inhibiting the migration and invasion mechanisms of RA-FLS. The intrinsic mechanism is to decrease matrix metalloproteinases (MMP-2) and MMP-9 and increase the protein expression of their complexes TIMP-1, TIMP-2 in RA-FLS. At the same time, WMP also reduced TNF and IL-6 levels in RA-FLS- α, acting through inhibition of TLR4-NF-κB inflammatory pathway activation. In in vivo experiments, WMP (0.5g/kg, 2kg/kg) alleviated arthritis and immune organ indices in type II collagen-induced rheumatoid arthritis model-CIA rats. Pathological section results showed that WMP suppressed knee joint swelling and inflammatory infiltration in CIA rats.
Conclusions
WMP plays a significant role in alleviating the course of RA. The specific mechanism is to inhibit the classical TLR4-NF-κB inflammatory pathway and reduce the secretion of inflammatory factors in the serum of RA -FLS and CIA rats. In addition, it regulates the dynamic balance of MMP-2/TIMP-2, MMP-9/TIMP-1, modulates the mechanism of RA-FLS invasion, and protects articular cartilage tissues in RA.
Roof Movement and Instability Fracture Characteristics in Shallow-Buried Thin Coal Seam Conventional Mining Faces
Authors: Zhang Jihua , Rui Qiao , Yang Yushun , Chen Jiarui , Shen Wei , Yuan Yue , Wang Chengwu , Liu Weili 
Published: October 2023

Abstract
The variation in the width of the mining face significantly affects the stability of the face, leading to potential roof fracturing and collapse. Additionally, strong coal and rock pressure can manifest, severely impeding the safe production of coal mines. This study uses the 16705 conventional working faces of Jinda Coal Mine as its engineering background to investigate the characteristics of roof strata movement and instability under conditions of variable-width mining in shallow-buried thin coal seams. First, using the key strata theory, the study estimates the dynamic load of the roof strata. Next, a mechanical model analysis of the roof strata movement in the working face is presented. This analysis shows the impact of different dimensions of the overhanging plate structure and residual overhanging structures in the corner on roof movement and its associated fracture mechanics. The findings indicated that as the roof width increases, the maximum bending deformation, deformation moment, and deformation stress rise logarithmically. Similarly, with an increased overhanging span of the roof, these metrics increase exponentially. In addition, as the size of the residual overhanging structures in the corner grows, these parameters rise linearly. Finally, this study analyzes the effect of roof instability on overlying pressure and estimates both the initial fracture step length and cyclic movement fracture step length of the roof. These insights offer valuable scientific guidance and a theoretical foundation for analyzing the adaptability of load-bearing pillars pressure in thin coal seam mining faces, bearing significant relevance to safety production.