bluuebunny/crossref_metadata_2025_split huggingface dataset:
Formation of the French Porcelain Collection at the Bohdan and Varvara Khanenko National Museum of Arts. Analysis of the Archive
Authors: Kravchenko Liudmyla 
Published: October 2023

The purpose of the article is to investigate the history of the formation of the French porcelain collection in the Bohdan and Varvara Khanenko National Museum of Arts; to study the available archival documents related to the collection of Bohdan Khanenko and late arrivals of decorative art to the museum's funds; to analyse the museum policy of the Soviet government in the 1920s - 1950s using the example of the Khanenko Museum. The research methodology is based on the use of methods: source studies – for the systematisation and classification of archival sources, comparative and analytical – for the identification of works of art. The scientific novelty consists in the systematisation of archival data on the formation of the French porcelain collection at the Khanenko Museum; generalisation of the main cultural and historical conditions for the formation of the museum collection of porcelain. Conclusions. One third of the French porcelain collection was collected by the founders of the museum, Bohdan and Varvara Khanenko, at the end of the 19th and the beginning of the 20th centuries, the second part arrived to the museum in 1927 from the Leningrad Department of the State Museum Fund (private collections until 1919), the third part – late arrivals in the 1930s - 1950s mainly from the Kyiv Museum of Russian Art (today the National Museum Kyiv Art Gallery), and the rest remain of uncertain origin.
Keywords: Bohdan and Varvara Khanenko National Museum of Arts, porcelain, history of collecting, collection formation.
Hubungan Kepadatan Parasit Terhadap Kadar Hemoglobin Pada Penderita Malaria Asimtomatik Di Gunung Sari
Authors: Agustin Ermadiana , Resnhaleksmana Ersandhi , Getas I Wayan 
Published: October 2023

Malaria is an infectious disease that still provides a high morbidity rate in the world. Malaria affects almost all blood components, one of which is hemoglobin levels. In malaria infection, there is a decrease in hemoglobin levels due to the destruction of excessive red blood cells by the malaria parasite. Asymptomatic malaria infection plays an important role in malaria transmission as it is a major influence on ongoing treatment-based malaria control programs. The research objective in this study was to know the effects of parasite density on hemoglobin levels in patients with Asymptomatic Malaria disease in Gunung Sari. The research study used is an analytic observational study with a Cross-Sectional approach with the Accidental sampling method and the Consecutive sampling method. The result of the study is out of the 14 samples diagnosed with asymptomatic malaria, 12 people (85.7%) had a mild degree of parasitemia based on parasite density calculations (8-800 / μl), and 2 people (14.3%) had moderate degrees of parasitemia (801- 8800 / μl). As many as 6 people (42.9%) had normal Hb levels, and 8 people (57.1%) had Hb levels below normal values. The conclusion of this study proved that there is a significant correlation between parasite density and hemoglobin levels in asymptomatic malaria patients in Gunung Sari.
The Effect Of Vegetable Reception Development On Acceptance Of Patients’ Ordinary Food
Authors: Chandradewi AASP , Suranadi Luh , Sofiyatin Reni , Aprillia Indri 
Published: October 2023

Background: The challenge of providing food in the hospital that must be followed up immediately is that there are still many leftovers from the patient's nutrition. The remaining food needs to be paid attention to because the food the patient consumes will help meet energy and nutritional needs. The remaining food is still a lot of vegetables; poor vegetable processing due to the long cooking process will reduce the nutritional content of the vegetables. Processing vegetables is not only to get healthy and nutritious vegetables, but also in the processing, it is expected to produce vegetables that taste delicious and can be consumed by many people, meaning that in processing, you must also think about the acceptance of these foods.Research Methods: To determine the effect of developing vegetable recipes on the acceptability of patients' average food at Dompu Hospital. This study was a quasi-experimental study using a one-group pretest-posttest design. This study was conducted in May 2021. The population of this study was Class III patients, with a sample of 27 patients data analysis using an independent t-test. Research Result: The results showed that the most vegetable residue was scrambled vegetables, as much as 88.9%, while the least remaining vegetables, and corn cream soup, as much as 70.3%. The results of the statistical test conducted indicated that there was a significant difference in acceptance after modification of the vegetable recipe (p <0.05). Conclusion: The results of the modification stated that out of 27 samples, eight samples (29.7%) still left vegetables included in the category of many > 20%, and 19 samples (70.3%) used up vegetables so that they were included in the category of less <20%. The comparison of leftover vegetables before and after modification showed that the highest yield was found in scrambled vegetables, as much as 88.9%. In contrast, the fewest remaining vegetables were cream corn soup, as much as 70.3%.
PERSEPSI JUMLAH ANAK YANG DI INGINKAN REMAJA DI NUSA TENGGARA BARAT
Authors: Handayani Baiq Nining , Supinganto Agus , Setyawati Irni 
Published: October 2023

Setiap remaja harus memiliki pemahaman yang baik tentang nilai keluarga kecil atau jumlah anak ideal, sehingga remaja akan mampu dalam mempersiapkan diri dan kualitas anggota keluarga sebelum remaja melaksanakan pernikahan. Penelitian ini bertujuan untuk mengetahui persepsi jumlah anak yang diinginkan remaja di Nusa Tenggara Barat .Data yang digunakan adalah Survey Kinerja dan Akuntabilitas Program (SKAP) tahun 2019 dengan unit analisis remaja usia 15-24 tahun dan belum menikah. Analisis dilakukan dengan metode regresi logistik biner. Hasil anlisis menunjukkan bahwa sebagian besar menginginkan 2 anak cukup di masa yang akan datang.Faktor daerah tempat tinggal, keluarga yang menginginkan banyak anak dan program Generasi Berencana (GENRE) berpengaruh terhadap jumlah anak yang diinginkan oleh remaja.
PENGARUH PENDIDIKAN ANTENATAL DENGAN MEDIA BOOKLET TERHADAP PENGETAHUAN DAN KESIAPAN IBU HAMIL USIA DIBAWAH 20 TAHUN DALAM MENGHADAPI KEHAMILAN
Authors: Nurmayasari Nurmayasari , Ekayani Ni Putu Karunia 
Published: October 2023

Latar Belakang : Data RISKESDAS 2018 didapatkan kehamilan perempuan umur 10-54 tahun yang pernah kawin di NTB yaitu pernah hamil 94,1% dan sedang hamil 5,6%. Untuk kehamilan perempuan umur 10-19 tahun pernah hamil sebanyak 58,8% dan sedang hamil 25,2%.Tujuan Penelitian : Mengetahui pengaruh pendidikan antenatal dengan media booklet terhadap pengetahuan dan kesiapan ibu hamil usia dibawah 20 tahun dalam menghadapikehamilan.Metode Penelitian : Penelitian ini adalah Quasi experiment dengan one group pretest-posttest. Penelitian ini dilaksanakan bulan Mei-Juni 2019. Populasi dalam penelitian ini ibu hamil usia dibawah 20 tahun bertempat tinggal di wilayah kerja UPT BLUD Puskesmas Gerung yaitu 32 ibu hamil. Sampel 30 ibu hamil. Analisis menggunakan Wilcoxon Sign Rank Test dan Paired Sample TTest.Hasil Penelitian : Responden dalam penelitian ini berusia 16-19 tahun dengan mayoritas pendidikan menengah dan semua bekerja sebagai ibu rumah tangga. Terdapat peningkatan nilai tingkat pengetahuan dan kesiapan dari sebelum dan setelah diberikan intervensi. Hasil uji statistik tingkat pengetahuan dan kesiapan diperoleh nilai p = 0,000.Kesimpulan : ada pengaruh pendidikan antenatal terhadap pengetahuan dan kesiapan ibu hamil usia dibawah 20 tahun dalam menghadapi kehamilan. ABSTRACTTHE EFFECT OF ANTENATAL EDUCATION WITH THEBOOKLET MEDIA ON THE KNOWLEDGE AND READINESS OF PREGNANT WOMEN UNDER 20 YEARS IN FACING PREGNANCY AbstractBackground: Data from RISKESDAS 2018 found that pregnancies of women aged 10-54 years who had been married in NTB were pregnant with 94.1% and were pregnant 5.6%. For pregnancy, women aged 10-19 years have been pregnant as much as 58.8% and are pregnant25.2%.Research Objectives: To determine the effect of antenatal education with booklet media on the knowledge and readiness of pregnant women under the age of 20 in the face of pregnancy.Research Methods: This study was a Quasi experiment with one group pretest-posttest. The research was conducted in May-June 2019. The population in this study were pregnant women under the age of 20 years living in the work area of the UPT BLUD Puskesmas Gerung, namely 32 pregnant women. Sample of 30 pregnant women. Analysis using the Wilcoxon Sign Rank Test and Paired Sample TTest.Results: Respondents in this study were 16-19 years old with the majority of secondary education and all working as housewives. There is an increase in the value of the level of knowledge and readiness from before and after the intervention is given. The statistical test results of the level of knowledge and readiness obtained p = 0,000.Conclusion :the influence of antenatal education on the knowledge and readiness of pregnant women under 20 years of age in the face of pregnancy.
HUBUNGAN USIA DAN PARITAS IBU HAMIL DENGAN KEJADIAN ABORTUS DI PUSKESMAS SAPE KABUPATEN BIMA
Authors: Aprilia Nova , Nursetiawati Nursetiawati , Nurhidayah Nurhidayah 
Published: October 2023

Perbaikan kesehatan ibu telah menjadi prioritas utama dari pemerintah, berbagai upaya telah dilakukan dalam meningkatkan kesehatan ibu dan anak terutama pada kelompok yang paling rawan yaitu ibu hamil, bersalin dan nifas, serta bayi baru lahir.Berdasarkan permasalahan tersebut maka penelitian ini bertujuan Untuk mengetahui apakah ada hubungan usia dan paritas ibu hamil dengan kejadian abortus di Puskesmas Sape Kabupaten Bima.penelitian menggunakan rancangan observasional analitik dengan pendekatan cross sectional. Populasi adalah semua ibu hamil yang melakukan pemeriksaan kehamilan trimester I di Puskesmas Sape bulan Mei s/d Juli tahun 2021.Sampel yang digunakan 50 ibu hamil.Instrumen menggunakan Rekam Medik ibu hamil yang melakukan pemeriksaan kehamilan di Puskesmas Sape Kabupaten Bima. Analisis data dengan uji chi square menggunakan SPSS versi 16.Penelitian menunjukan usia ibu hamil tidak beresiko yaitu sejumlah 39 orang (78%) dan paritas tidak beresiko yaitu sebanyak 45 responden (90%), serta responden yang mengalami abortus sejumlah 39 orang (78%). Hasil analisis uji chi square diperoleh nilai Pvalue = 0,633 ≥ (α)= 0,05 dengan demikian tidak terdapat hubungan antara usia dengan kejadian abortus di Puskesmas Sape. Hasil analisis uji chi square antara paritas dengan kejadian abortus diperoleh nilai Pvalue = 0,909, ≥ (α)= 0,05, tidak terdapat hubungan antara paritas dengan kejadian abortus di Puskesmas Sape.Usia dan paritas bukan faktor penyebab terjadinya tingginya kejadian abortus. faktor lain penyebab terjadinya abortus status gizi, sosial, ekonomi, disarankan Puskesmas (Bidan) agar lebih meningkatkan lagi kualitas pelayanan untuk menurunkan angka kejadian abortus.
Penegakan Hukum Kepolisian dalam Pengungkapan Tindak Pidana Narkotika dengan Teknik Undercover Buy (Polres Kolaka Utara)
Authors: Irabiah  , Arief Mamba Muhammad As Ari , Mayasari Riezka Eka , Mafing Muhammad Ali Alala , Yahyanto  , Junaedy Akhmad 
Published: October 2023

This study aims to determine Police Law Enforcement in Disclosing Narcotics Crimes Using the Undercover Buy Technique at North Kolaka Police Station. The formulation of the problem posed is: What are the legal strengths and consequences for undercover buys made by non-Police members (informants)? and What are the obstacle factors in uncovering narcotics crimes with the Undercover Buy Technique?. The type of research used by the author in the preparation of this thesis final project is research that uses empirical research methods. The empirical legal research method is a legal research method that functions to see the law in a real sense and research how the law works in society. Covert Purchase as stipulated in Law No. 22 of 1997 which has been changed to Law No. 35 of 2009 is an addition to the investigator's authority in efforts to eradicate narcotics trafficking. This is because narcotics crimes are organized, secret crimes, and in practice they use sophisticated modus operandi and technology, making it difficult to collect evidence. Unlike other criminal acts, the implementation of covert purchases in narcotics crimes is not contrary to human rights if carried out in accordance with applicable regulations. However, it will be different if it is not implemented in accordance with applicable regulations. This is because the implementation of covert purchases cannot be separated from the participation of the community, so that the rights of the people who participate must be protected. In order to reduce errors and the implementation of covert purchases, it is necessary to know and understand clearly by investigators regarding the implementation of covert purchases themselves as stipulated in Law No. 35 of 2009.
Keywords: Law Enforcement, Narcotics, Undercover Buy
Amino acid profile in overweight and obese prepubertal children – can simple biochemical tests help in the early prevention of associated comorbidities?
Authors: Bugajska Jolanta , Berska Joanna , Wójcik Małgorzata , Sztefko Krystyna 
Published: October 2023

BackgroundIt is accepted that plasma branched-chain amino acids (BCAAs) and aromatic amino acids (AAAs) are closely related to metabolic risk. Arterial hypertension, metabolic syndrome, endothelial dysfunction, inflammation, and metabolic dysfunction-associated fatty liver disease (MAFLD) are frequently seen in obese patients. Many attempts have been made to find biochemical indicators for the early detection of metabolic complications in children. It is not known if different amino acid profiles and BCAA and AA concentrations in overweight and obese children correlate with chemerin, proinflammatory, and simple biochemical markers. Thus, the study aimed to find out the early markers of cardiovascular disease and MAFLD in overweight and obese children.Materials and methodsThe study included 20 overweight and obese children (M/F 12/8; mean age 7.7 ± 2.3 years; BMI 26.8 ± 5.0 kg/m2) and 12 non-obese children (control group) (M/F 4/8; mean age 6.5 ± 2.2 years; BMI 14.8 ± 1.5 kg/m2). The following plasma amino acids were measured: aspartic acid, glutamic acid, serine, asparagine, glycine, glutamine, taurine, histidine, citrulline, threonine, alanine, arginine, proline, tyrosine, methionine, valine, isoleucine, leucine, phenylalanine, tryptophan, ornithine, and lysine. Chemerin, high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), and basic biochemistry parameters were measured.ResultsThe mean plasma levels of leucine, isoleucine, valine, phenylalanine, tyrosine, glutamic acid, and alanine were significantly higher in overweight and obese children than in the control group (p&lt;0.03–p&lt;0.0004). Conversely, the mean values of serine, asparagine, glutamine, and citrulline were significantly lower in overweight and obese children than in the control group (p&lt;0.03–p&lt;0.0007). Isoleucine, leucine, valine (BCAAs) tyrosine, and phenylalanine (AAAs) levels showed a positive correlation with uric acid, ALT, hs-CRP, and chemerin (r=0.80–0.36; p&lt;0.05-p&lt;0.00001), but not with IL-6. The mean values of glucose, IL-6, hs-CRP, chemerin, uric acid, and ALT were significantly higher in overweight and obese children than in the control group (p&lt;0.03–p&lt;0.00002). In contrast, the lipid profile did not differ between groups.ConclusionAn abnormal amino acid profile in overweight and obese pre-pubertal children, accompanied by elevated ALT and UA observed in the studied cohort, may suggest early metabolic disturbances that can potentially lead to metabolic syndrome, or MAFLD, and increased cardiovascular risk.
The slan antigen identifies the prototypical non-classical CD16+-monocytes in human blood
Authors: Tamassia Nicola , Bianchetto-Aguilera Francisco , Gasperini Sara , Grimaldi Alessio , Montaldo Claudia , Calzetti Federica , Gardiman Elisa , Signoretto Ilaria , Castellucci Monica , Barnaba Vincenzo , Tripodi Marco , Cassatella Marco Antonio 
Published: October 2023

IntroductionPeripheral monocytes in humans are conventionally divided into classical (CL, CD14++CD16−), intermediate (INT, CD14++CD16+) and non-classical (NC, CD14dim/−CD16++) cells, based on their expression levels of CD14 and CD16. A major fraction of the NC-monocytes has been shown to express the 6-sulfo LacNAc (slan) antigen, but whether these slan+/NC-monocytes represent the prototypical non-classical monocytes or whether they are simply a sub-fraction with identical features as the remainder of NC monocytes is still unclear.MethodsWe analyzed transcriptome (by bulk and single cell RNA-seq), proteome, cell surface markers and production of discrete cytokines by peripheral slan+/NC- and slan−/NC-monocytes, in comparison to total NC-, CL- and INT- monocytes.ResultsBy bulk RNA-seq and proteomic analysis, we found that slan+/NC-monocytes express higher levels of genes and proteins specific of NC-monocytes than slan−/NC-monocytes do. Unsupervised clustering of scRNA-seq data generated one cluster of NC- and one of INT-monocytes, where all slan+/NC-monocytes were allocated to the NC-monocyte cluster, while slan−/NC-monocytes were found, in part (13.4%), within the INT-monocyte cluster. In addition, total NC- and slan−/NC-monocytes, but not slan+/NC-monocytes, were found by both bulk RNA-seq and scRNA-seq to contain a small percentage of natural killer cells.ConclusionIn addition to comparatively characterize total NC-, slan−/NC- and slan+/NC-monocyte transcriptomes and proteomes, our data prove that slan+/NC-, but not slan−/NC-, monocytes are more representative of prototypical NC-monocytes.
Ultrasound radiomics based on axillary lymph nodes images for predicting lymph node metastasis in breast cancer
Authors: Tang Yu-Long , Wang Bin , Ou-Yang Tao , Lv Wen-Zhi , Tang Shi-Chu , Wei An , Cui Xin-Wu , Huang Jiang-Sheng 
Published: October 2023

ObjectivesTo determine whether ultrasound radiomics can be used to distinguish axillary lymph nodes (ALN) metastases in breast cancer based on ALN imaging.MethodsA total of 147 breast cancer patients with 41 non-metastatic lymph nodes and 109 metastatic lymph nodes were divided into a training set (105 ALN) and a validation set (45 ALN). Radiomics features were extracted from ultrasound images and a radiomics signature (RS) was built. The Intraclass correlation coefficients (ICCs), Spearman correlation analysis, and least absolute shrinkage and selection operator (LASSO) methods were used to select the ALN status–related features. All images were assessed by two radiologists with at least 10 years of experience in ALN ultrasound examination. The performance levels of the model and radiologists in the training and validation subgroups were then evaluated and compared.ResultRadiomics signature accurately predicted the ALN status, achieved an area under the receiver operator characteristic curve of 0.929 (95%CI, 0.881-0.978) and area under curve(AUC) of 0.919 (95%CI, 95%CI, 0.841-0.997) in training and validation cohorts respectively. The radiomics model performed better than two experts’ prediction of ALN status in both cohorts (P&lt;0.05). Besides, prediction in subgroups based on baseline clinicopathological information also achieved good discrimination performance, with an AUC of 0.937, 0.918, 0.885, 0.930, and 0.913 in HR+/HER2-, HER2+, triple-negative, tumor sized ≤ 3cm and tumor sized&gt;3 cm, respectively.ConclusionThe radiomics model demonstrated a good ability to predict ALN status in patients with breast cancer, which might provide essential information for decision-making.
Application of serum Raman spectroscopy combined with classification model for rapid breast cancer screening
Authors: Lin Runrui , Peng Bowen , Li Lintao , He Xiaoliang , Yan Huan , Tian Chao , Luo Huaichao , Yin Gang 
Published: October 2023

IntroductionThis study aimed to evaluate the feasibility of using general Raman spectroscopy as a method to screen for breast cancer. The objective was to develop a machine learning model that utilizes Raman spectroscopy to detect serum samples from breast cancer patients, benign cases, and healthy subjects, with puncture biopsy as the gold standard for comparison. The goal was to explore the value of Raman spectroscopy in the differential diagnosis of breast cancer, benign lesions, and healthy individuals.MethodsIn this study, blood serum samples were collected from a total of 333 participants. Among them, there were 129 cases of tumors (pathologically diagnosed as breast cancer and labeled as cancer), 91 cases of benign lesions (pathologically diagnosed as benign and labeled as benign), and 113 cases of healthy controls (labeled as normal). Raman spectra of the serum samples from each group were collected. To classify the normal, benign, and cancer sample groups, principal component analysis (PCA) combined with support vector machine (SVM) was used. The SVM model was evaluated using a cross-validation method. ResultsThe results of the study revealed significant differences in the mean Raman spectra of the serum samples between the normal and tumor/benign groups. Although the mean Raman spectra showed slight variations between the cancer and benign groups, the SVM model achieved a remarkable prediction accuracy of up to 98% for classifying cancer, benign, and normal groups. DiscussionIn conclusion, this exploratory study has demonstrated the tremendous potential of general Raman spectroscopy as a clinical adjunctive diagnostic and rapid screening tool for breast cancer.
Associations of multi-human papillomavirus infections with expression of p16 in a cohort of women who underwent colposcopy: a retrospective study of 5165 patients
Authors: Zhang Yulong , Li Haibo , Li Xiaowen , Li Zelong , You Qianru , Liu Hanwen , Zhao Zhiyan , Su Yanzhao , Zheng Xiangqin , Chen Yusha , Chen Jiancui , Yi Huan 
Published: October 2023

ObjectiveInvestigate HPV types in cervical specimens, their correlation with p16 expression in lesions, and diagnostic value for cervical lesions. Enhance clinical diagnosis reliability.MethodsRetrospective cross-sectional study at Fujian Maternity and Child Health Hospital’s Cervical Disease Center (Jun 2019-Dec 2021). Patients with abnormal cervical screening underwent colposcopy and conization. Pathological diagnosis based on colposcopy, cervical biopsy, ECC, and conization. Analyzed HPV genotyping (18 HR-HPV, 5 LR-HPV) and p16 expression correlation. Statistical analysis used R software.Resultshe expression of p16 is significantly associated with the infection of high-risk HPV types, such as 16, 33, 52, and 58, with an increased risk of 1.4 times or higher (OR=1.91, 3.14, 1.40, and 1.78, respectively). The risk of p16 expression increased 4-fold for multiple high-risk HPV types [adjusted OR (95% CI) = 4 (2.92~5.5), P-value &lt;0.001]. Compared to the p16(-) group, the p16(+) group had a higher association with cervical lesions worse than HSIL (High-grade Squamous Intraepithelial Lesions).In the group with multiple Human Papillomavirus Infections with types 16, 33, 52, and 58, the risk of cervical lesions worse than HSIL increased by up to 660-fold compared to the negative group (adjusted OR=660.62, 95% CI: 91.39~4775.53, P&lt;0.001), indicating that this combination of HPV types posed the greatest risk for cervical lesions above HSIL.Conclusionsp16 plays a crucial role in cervical lesion progression, linked to high-risk HPV. Combining p16 with HPV screening improves cervical cancer detection. Studying multiple HPV infections will enhance prevention and management.