bluuebunny/crossref_metadata_2025_split huggingface dataset:
A systematic review suggests extension and redefinition of a food-deception pollination syndrome involving anautogenous flies
Authors: Vrecko Valentin , Proffit Magali , Kidyoo Aroonrat , McKey Doyle , Blatrix Rumsais 
Published: January 2025

Abstract

Background and Aims
The currently recognized diversity of pollination strategies requires pollination syndromes to be updated. Described a decade ago, kleptomyiophily is a deceptive pollination system in which plants exploit the nutrient-seeking behaviour of females of kleptoparasitic flies (Chloropidae and Milichiidae) by olfactorily mimicking their insect host. Such a pollination system was already hypothesized for pollination by biting midges (Ceratopogonidae) but has never been formalized. This review aims to explore the extent of pollination interactions deceiving anautogenous flies, especially by considering pollination by biting midges and kleptomyiophily as two facets of a common pollination syndrome: insect-host mimicry. Given that attraction of these flies seems to rely on insect-mimicking volatile organic compounds (VOCs), we propose an overview of the floral odours emitted by these plant species.

Methods
We compiled bibliographic data on plant species pollinated by Chloropidae, Ceratopogonidae and Milichiidae, to list plant species that could be involved in insect-host mimicry pollination strategies. Then, we reanalysed data from the literature on floral VOCs of 18 of these plant species distributed among four plant families and compared them with related plant species performing brood-site mimicry, the pollination syndrome closest to insect-host mimicry.

Results
We show that 97 plant species from seven families are mainly pollinated by Chloropidae, Ceratopogonidae and Milichiidae, with almost exclusively females found in flowers. Deception of anautogenous flies has been shown for only four plant species but has been supposed for a total of 28 others. Comparison of floral VOCs shows significant differences between insect-host mimicry and brood-site mimicry in terms of chemical composition, diversity and models mimicked.

Conclusions
Despite fragmentary knowledge about the biology of the Diptera involved in insect-host mimicry, our results show similarities in floral odours and the putative mimicked resource between kleptomyiophilous plants and those pollinated by biting midges, emphasizing a broader, unique, pollination syndrome.
A bioinformatician, computer scientist, and geneticist lead bioinformatic tool development—which one is better?
Authors: Gardner Paul P 
Published: January 2025

Abstract

Motivation
The development of accurate bioinformatic software tools is crucial for the effective analysis of complex biological data. This study examines the relationship between the academic department affiliations of authors and the accuracy of the bioinformatic tools they develop. By analyzing a corpus of previously benchmarked bioinformatic software tools, we mapped bioinformatic tools to the academic fields of the corresponding authors and evaluated tool accuracy by field.

Results
Our results suggest that “Medical Informatics” outperforms all other fields in bioinformatic software accuracy, with a mean proportion of wins in accuracy rankings exceeding the null expectation. In contrast, tools developed by authors affiliated with “Bioinformatics” and “Engineering” fields tend to be less accurate. However, after correcting for multiple testing, no result is statistically significant (P &gt; .05). Our findings reveal no strong association between academic field and bioinformatic software accuracy. These findings suggest that the development of interdisciplinary software applications can be effectively undertaken by any department with sufficient resources and training.

Availability and implementation
All data and the analysis pipeline for this study are freely available online at the GitHub repository: https://github.com/ppgardne/departments-software-accuracy.
Redefining diagnostic lesional status in temporal lobe epilepsy with artificial intelligence
Authors: Gleichgerrcht Ezequiel , Kaestner Erik , Hassanzadeh Reihaneh , Roth Rebecca W , Parashos Alexandra , Davis Kathryn A , Bagić Anto , Keller Simon S , Rüber Theodor , Stoub Travis , Pardoe Heath R , Dugan Patricia , Drane Daniel L , Abrol Anees , Calhoun Vince , Kuzniecky Ruben I , McDonald Carrie R , Bonilha Leonardo 
Published: January 2025

Abstract
Despite decades of advancements in diagnostic MRI, 30-50% of temporal lobe epilepsy (TLE) patients remain categorized as “non-lesional” (i.e., MRI negative or MRI–) based on visual assessment by human experts. MRI– patients face diagnostic uncertainty and significant delays in treatment planning. Quantitative MRI studies have demonstrated that MRI– patients often exhibit a TLE-specific pattern of temporal and limbic atrophy that may be too subtle for the human eye to detect. This signature pattern could be successfully translated into clinical use via artificial intelligence (AI) advances in computer-aided MRI interpretation, thereby improving the detection of brain “lesional” patterns associated with TLE.
Here, we tested this hypothesis by employing a three-dimensional convolutional neural network (3D CNN) applied to a dataset of 1,178 scans from 12 different centers. 3D CNN was able to differentiate TLE from healthy controls with high accuracy (85.9% ± 2.8), significantly outperforming support vector machines based on hippocampal (74.4% ± 2.6) and whole-brain (78.3% ± 3.3) volumes. Our analysis subsequently focused on a subset of patients who achieved sustained seizure freedom post-surgery as a gold standard for confirming TLE.
Importantly, MRI– patients from this cohort were accurately identified as TLE 82.7% ± 0.9 of the time, an encouraging finding since clinically these were all patients considered to be MRI– (i.e., not radiographically different than controls). The saliency maps from the CNN revealed that limbic structures, particularly medial temporal, cingulate, and orbitofrontal areas, were most influential in classification, confirming the importance of the well-established TLE signature atrophy pattern for diagnosis. Indeed, the saliency maps were similar in MRI+ and MRI– TLE groups, suggesting that even when humans cannot distinguish more subtle levels of atrophy, these MRI– patients are on the same continuum common across all TLE patients. As such, AI can identify TLE lesional patterns and AI-aided diagnosis has the potential to greatly enhance the neuroimaging diagnosis of TLE and redefine the concept of “lesional” TLE.
Philosophy, practice, and politics of community development: lessons from extension fieldwork in Newfoundland, 1960–1982
Authors: McLean Scott 
Published: January 2025

Abstract
One of the most significant community development initiatives in Canadian history was sponsored by Memorial University of Newfoundland (MUN) from 1960 to 1982. Fieldworkers employed by MUN Extension worked across the province of Newfoundland and Labrador, engaging in strategies of community change that included social action, citizen participation, public advocacy, local services development, and popular education. The fieldworkers were guided by a philosophy of community development that positioned their work as politically neutral, non-directive, and educational in nature. In the latter 1970s, this philosophy—along with the community development practices it supported—was challenged by institutional changes that required fieldworkers to engage in externally directive projects oriented towards natural resource development. This historical case study of the evolution of community development philosophy and practice in Canada has important implications for contemporary scholars and practitioners elsewhere. Those implications include the importance of understanding both the institutional politics of organizations through which community development work occurs and the socio-political realities of the communities served by those organizations. Readers of this article will appreciate its nuanced account of a major community development initiative and will be inspired to reflect upon the institutional and socio-political context of their own work.
Impact of Fluconazole on Outcomes of Patients With Primary Pulmonary Coccidioidomycosis: A Commercial Health Insurance Claims-based, Propensity Score Matched Analysis
Authors: Benedict Kaitlin , Hennessee Ian , Smith Dallas J , Toda Mitsuru , Thompson George R 
Published: January 2025

Abstract

Background
Patients with pulmonary coccidioidomycosis often experience prolonged symptoms lasting from weeks to months. Limited data exist regarding whether fluconazole prevents development of disseminated disease or shortens symptom duration. We describe factors associated with fluconazole receipt and assess its effect on outcomes among patients with pulmonary coccidioidomycosis.

Methods
Using the MerativeTM MarketScan® Commercial Database, we identified immunocompetent patients ages 18–64 with incident pulmonary coccidioidomycosis during 2017–2023 and continuous enrollment in the 180 days before and after diagnosis. We examined demographic and clinical differences between patients treated versus not treated with fluconazole and performed 1:1 greedy nearest neighbor propensity score matching to control for these differences. We performed bivariate analyses on the matched subset to evaluate patient outcomes by fluconazole receipt.

Results
Among 1448 patients with pulmonary coccidioidomycosis, 659 (46%) received fluconazole. Patients who received fluconazole more frequently had pre-diagnosis symptoms (95% vs 72%, P &lt; .001) and antibiotic prescriptions (68% vs 32%, P &lt; .001) than those who did not. Among the propensity score matched subset (n = 696), hospitalization (4% vs 1%, P = .004) and disseminated coccidioidomycosis (3% vs 0%, P = .006) were more frequent among patients who received fluconazole. The median number of days from diagnosis to last visit for chest pain (50.0 vs 46.5), cough (64.0 vs 39.0), fatigue (63.0 vs 65.5), myalgia (98.0 vs 74.0), and joint pain (93.5 vs 107.5) was not significantly different between treatment groups.

Conclusions
Our results support existing guidelines that fluconazole may not be associated with improved outcomes for certain immunocompetent patients with pulmonary coccidioidomycosis.
Improving recommendation fairness with dependency-based graph collaborative filtering
Authors: Wen Xiaoyang , Guan Shaopeng 
Published: January 2025

Abstract
Collaborative filtering recommendation systems that utilize graph convolutional neural networks (GCNs) often emphasize on training speed and accuracy, while overlooking the critical issue of fairness. This paper introduces FairGCF, a novel graph-based collaborative filtering model designed to address fairness concerns in GCN-based recommendations. FairGCF improves the representational capacity of graph collaborative filtering models by identifying dependencies between nodes in the graph, resulting in fairer and more accurate recommendations. The model constructs a dependency graph between users and items to capture higher order interaction patterns, aggregating features from users and items with similar dependencies to enrich their representations. Additionally, a fairness loss factor is incorporated to minimize disparities between positive and negative samples, thereby promoting fairness. Experiments on three public datasets demonstrate that FairGCF improves the Recall metric by an average of 6%, NDCG by 8.79%, Precision by 3.68%, and F1 score by 3.62%. Notably, the model is carefully designed to avoid bias toward specific users or items.
Characterization of two cellular superoxide dismutases in Protohermes xanthodes (Megaloptera: Corydalidae) in response to sublethal chlorpyrifos stress
Authors: Yang Jie , Wen Xi , Huang Xingrui , Zou Jie , Lu Yun , Yuan Fang , Xiao Sijie , Tang Xiaochao , Liu Zhixiao , Wu Zhengwei , Huang Xinglong 
Published: January 2025

Abstract
Pesticides released into the environment are increasingly recognized as a global threat to freshwater ecosystems because of their adverse effects on non-target organisms, particularly aquatic insects and other arthropods. Superoxide dismutases (SODs) are important antioxidant enzymes that play a crucial role in protecting organisms from oxidative stress induced by harmful materials. In this study, we identified 2 cellular SODs (PxSOD1 and PxSOD2) in Protohermes xanthodes Navás (Megaloptera: Corydalidae), an freshwater predatory insect, and determined the oxidative stress induced in P. xanthodes larvae by sublethal exposure to chlorpyrifos (CPF). PxSOD1 and PxSOD2 are members of the cytoplasmic Cu/ZnSODs and mitochondrial MnSODs, respectively, and differ substantially in protein structure. Both PxSOD1 and PxSOD2 recombinant proteins demonstrated catalytic activity toward O2•− in the activity assays. After exposure to sublethal concentrations of CPF, malondialdehyde (MDA) content and SOD activities were increased in P. xanthodes larvae in a dose-dependent manner. PxSOD1 expression was decreased in the 0.42 and 4.2 μg/L CPF groups and increased in the 4.2 μg/L CPF group. PxSOD2 was upregulated by 0.42, 4.2, and 8.4 μg/L CPF treatments and the expression levels in the 4.2 and 8.4 μg/L CPF groups were significantly higher than that in the no CPF control. Our results suggest that sublethal concentrations of CPF can induce oxidative stress in P. xanthodes larvae, and the cellular SODs in P. xanthodes larvae may contribute to the protection against CPF-induced oxidative stress.
Two types of double chambered left ventricle: a case series
Authors: Fang Aijuan , Liu Lei , Chen Hui , Ma Xiuling , Yu Hongming , Yao Jing 
Published: January 2025

Abstract

Background
Double chambered left ventricle (DCLV) is a rare anatomical variant of the left ventricular structure characterized by the division of the left ventricle into two distinct chambers due to abnormal muscle bundles or septa. This anomaly typically results in primary and secondary chambers within the left ventricle. Due to the lack of conspicuous clinical symptoms, DCLV is often overlooked.

Case summary
The first patient was a 69-year-old male experiencing intermittent chest tightness for several weeks. Transthoracic echocardiography indicated the presence of Type A DCLV, which was subsequently confirmed by 3D echocardiography and cardiac magnetic resonance imaging. An additional case is also worthy of note, during a routine transthoracic echocardiographic examination of a 48-year-old male, we unexpectedly discovered Type B DCLV. His unique cardiac structure was clearly demonstrated through 3D echocardiography.

Discussion
Double chambered left ventricle is a rare structural heart malformation often overlooked due to atypical symptoms. This paper presents two cases of DCLV, illustrating two distinct classifications. Comprehensive understanding of the imaging manifestations of DCLV is imperative for accurate clinical diagnosis.
Late gadolinium enhancement in mid infero-septal area after left bundle branch area pacing in the setting of bifascicular block and syncope: a case report
Authors: Redzepi Betim , Bengueddache Samir , Schwitter Juerg , Antiochos Panagiotis , Pruvot Etienne 
Published: January 2025

Abstract

Background
Conduction system pacing, which includes His bundle pacing and left bundle branch area pacing (LBBAP), is becoming increasingly common in clinical practice. His bundle pacing, introduced over two decades ago, continues to see growing use, while LBBAP is gaining traction due to its broader target area and shorter procedure times. However, complications such as septal perforation and lead-related issues may still arise. This case report explores the evaluation and management of recurrent syncope in the context of bifascicular block (BFB), highlighting the importance of thorough assessment, continuous ECG monitoring, and the potential need for permanent pacemaker implantation.

Case summary
A 60-year-old woman with a history of myocardial infarction, Type II diabetes, and dyslipidaemia presented with recurrent syncope and BFB, for which a LBBAP device was implanted in August 2023. In February 2024, she was admitted again due to recurrent syncope and frequent premature ventricular contractions. Cardiac magnetic resonance imaging revealed two localized myocardial scars: one at the basal anterior wall from the 2018 ischaemic event and another in the mid infero-septal wall at the site of the LBBAP lead. During her hospital stay, she experienced multiple episodes of near fainting due to orthostatic hypotension, indicative of underlying autonomic neuropathy.

Discussion
This narrative explores the evolving landscape of cardiac pacing techniques, with a focus on LBBAP, highlighting its advantages over traditional methods while also acknowledging potential complications. Additionally, it emphasizes the importance of a comprehensive workup for syncope and the need for tailored interventions that extend beyond pacemaker implantation.
From In(-)formation to Infrastructural Turns: The Digital Futures of Human Rights Law and Practice
Authors: Fisher Angelina 
Published: January 2025

Abstract
In his book, The Informational Logic of Human Rights: Network Imaginaries in the Cybernetic Age, Joshua Bowsher critiques the human rights movement’s preoccupation with informational practices. Tracing the evolution of informational preoccupation of human rights organizations to the rise of cybernetics and its enmeshment with the neo-liberal project, Bowsher argues that the resulting practice of creating violations as events through capturing, cutting and noise elimination has defanged and depoliticized rights. The quest for objective, stable and predictable knowledge has permeated even the turn to algorithms and machine learning. While denouncing the human rights movement’s resistance to critical and political forms of knowledge making that interrogate subjects, norms, values and power relations, Bowsher nonetheless sees potential for salvaging the promise of human rights. What is needed, Bowsher argues, is a reconfiguration of human rights information from an assemblage of ‘brute facts’ into positional, situated knowledge-making practice that would aim to forge connections between structures of oppression and domination and sufferings of ‘particularly situated human beings’. Picking up on Bowsher’s call for human rights in(-)formation, this review essay examines the infrastructural turn needed to effectuate knowledge-generating practices attuned to the polyvalency of the situated perspectives. Focusing particularly on the growing role of digital data and infrastructures, the essay seeks to illuminate promising paths forward for human rights advocates and practitioners.
The pollution fast-track to the Arctic: how southern wintering areas contribute to organochlorine loads in a migrant seabird breeding in the Arctic
Authors: Bustnes Jan Ove , Bårdsen Bård-Jørgen , Moe Børge , Herzke Dorte , Bemmelen Rob S A van , Tulp Ingrid , Schekkerman Hans , Hanssen Sveinn-Are 
Published: January 2025

Abstract
This study examines how southern wintering areas may contribute to organochlorine (OCs) loads in arctic seabirds during breeding. Light-sensitive geolocators (GLS loggers) were deployed on Arctic skuas (Stercorarius parasiticus) in one high arctic and two subarctic colonies. Hexcahlorobenzene (HCB), chlordanes, mirex, p,p′-dichlorodiphenyldichloro-ethylene (p,p′-DDE), and polychlorinated biphenyls (PCBs) were measured in the blood of breeding adults at the nest (58 individuals, a total of 128 samples) in northern Norway and Svalbard between 2009 and 2015. We compared OC concentrations and OC profiles among nesting skuas wintering in five Atlantic regions, determined by the GLS loggers: the coast of Argentina, the Caribbean, off West Africa, off the coast of southern Africa, and the Mediterranean Sea. As predicted, HCB, which is semi-volatile and has high long-range transport potential, showed high prevalence in birds wintering in all regions except the Mediterranean. Mirex showed the highest prevalence in birds wintering off the coasts of Argentina and southern Africa, in accordance with high background levels previously documented in the Southern Ocean. Chlordanes were particularly prevalent in skuas wintering off southern Africa, whereas p,p′-DDE seemed relatively evenly distributed among wintering areas. As predicted, the prevalence of PCBs was much higher in birds wintering in the Mediterranean Sea than in birds from other regions. This study thus suggests that the Mediterranean Sea and the mid- and southern Atlantic are essential sources of different OCs in the blood of Arctic skuas breeding in the European Arctic.
Trade-offs of different types of dose-responses following temporal gradients of Pb stress in Tillandsia usneoides
Authors: Tang Zhen , Liu Yuanyuan , Agathokleous Evgenios , Han Shuo , Zheng Guiling , Li Peng 
Published: January 2025

Abstract
The dose-response relationship between toxicants and organisms is the most fundamental principle in toxicological risk assessment. However, multiphasic non-linear responses are poorly understood and the underlying mechanisms remain elusive. In this study, we subjected the indicator plant Tillandsia usneoides to 5 or 10 time gradients of 1 mM Pb, and assessed the response patterns of five damage markers and eight resistance markers in the leaves. The results showed that in the assay with 5 time gradients, 10 out of 13 biomarkers showed biphasic responses and 2 biomarkers showed multiphasic responses. In the assay with 10 time gradients, 6 biomarkers showed biphasic responses and 5 biomarkers showed multiphasic responses. The results confirmed that increasing the number of dose gradients facilitates the detection of multiphasic dose responses. Additionally, the occurrence of non-linear responses was found to be a common phenomenon. Further analysis of the frequency of trade-offs showed that the occurrence frequency of trade-off 2 (toxicants do not affect one marker but stimulate other markers), was always higher than that of trade-off 1 (toxicants worsen one marker while stimulating other markers) for both damage and resistance markers, and that trade-off 2 was more likely to appear in resistance markers. This suggests that, as the duration of stress increases, the body produces more resistance substances, which coordinate with one another to maintain internal balance. This study suggests that the trade-off theory can be effectively used to elucidate the complex relationship between a toxicant and T. usneoides.
Emerging live sonar technologies in freshwater recreational fisheries: Issues and opportunities
Authors: Cooke Steven J , Neely Ben C , Hasler Caleb T , Schooley Jason D , Brownscombe Jacob W , LaRochelle Luc , Danylchuk Andy J , Hunt Taylor L , Norman Jacob D 
Published: January 2025

Abstract
Debate about the potential benefits and risks of live sonar technology (also known as live imaging sonar and forward-facing sonar) in freshwater recreational fisheries includes growing discussions regarding regulation. Synthesizing sparse literature, experiences of the coauthors, and observations from traditional and social media, we revealed a varied range of potential outcomes for fisheries when this technology is used. Of particular concern is the ability to find fish that were previously cryptic and to target them in ways that increase capture efficiency (e.g., through snagging where legal or more accurately presenting lures or baits); thus, increasing catchability. Conflicting views within the recreational fishing community about the “fair chase” aspect of this technology have prompted discussions regarding regulations. We anticipate continued debate around this topic and hope that this paper will inspire more empirical research (ecological and human dimensions) to provide resource managers and the recreational fishing community with insights and guidance on how to ensure that live sonar is used in ways that benefit fisheries management and stakeholder interests.