bluuebunny/crossref_metadata_2025_split huggingface dataset:
Central Role of Nitrogen Fertilizer Relative to Water Management in Determining Direct Nitrous Oxide Emissions From Global Rice‐Based Ecosystems
Authors: Song Hanxiong , Zhu Qiuan , Blanchet Jean‐Pierre , Chen Zhi , Zhang Kerou , Li Tong , Zhou Feng , Peng Changhui 
Published: October 2023

AbstractThe increasing atmospheric nitrous oxide (N2O) concentration stems from the development of agriculture. However, N2O emissions from global rice‐based ecosystems have not been explicitly and systematically quantified. Therefore, this study aims to estimate the spatiotemporal magnitudes of the N2O emissions from global rice‐based ecosystems and determine different contribution factors by improving a process‐based biogeochemical model, TRIPLEX‐GHG v2.0. Model validation suggested that the modeled N2O agreed well with field observations under varying management practices at daily, seasonal, and annual steps. Simulated N2O emissions from global rice‐based ecosystems exhibited significant increasing trends from 0.026 ± 0.0013 to 0.18 ± 0.003 TgN yr−1 from 1910 to 2020, with ∼69.5% emissions attributed to the rice‐growing seasons. Irrigated rice ecosystems accounted for a majority of global rice N2O emissions (∼76.9%) because of their higher N2O emission rates than rainfed systems. Regarding spatial analysis, Southern China, Northeast India, and Southeast Asia are hotspots for rice‐based N2O emissions. Experimental scenarios revealed that N fertilizer is the largest global rice‐N2O source, especially since the 1960s (0.047 ± 0.010 TgN yr−1, 35.24%), while the impact of expanded irrigation plays a minor role. Overall, this study provides a better understanding of the rice‐based ecosystem in the global agricultural N2O budget; further, it quantitively demonstrated the central role of N fertilizer in rice‐based N2O emissions by including rice crop calendars, covering non‐rice growing seasons, and differentiating the effects of various water regimes and input N forms. Our findings emphasize the significance of co‐management of N fertilizer and water regimes in reducing the net climate impact of global rice cultivation.
The variable source of the plasma sheet during a geomagnetic storm
Authors: Kistler L. M. , Asamura K. , Kasahara S. , Miyoshi Y. , Mouikis C. G. , Keika K. , Petrinec S. M. , Stevens M. L. , Hori T. , Yokota S. , Shinohara I. 
Published: October 2023

AbstractBoth solar wind and ionospheric sources contribute to the magnetotail plasma sheet, but how their contribution changes during a geomagnetic storm is an open question. The source is critical because the plasma sheet properties control the enhancement and decay rate of the ring current, the main cause of the geomagnetic field perturbations that define a geomagnetic storm. Here we use the solar wind composition to track the source and show that the plasma sheet source changes from predominantly solar wind to predominantly ionospheric as a storm develops. Additionally, we find that the ionospheric plasma during the storm main phase is initially dominated by singly ionized hydrogen (H+), likely from the polar wind, a low energy outflow from the polar cap, and then transitions to the accelerated outflow from the dayside and nightside auroral regions, identified by singly ionized oxygen (O+). These results reveal how the access to the magnetotail of the different sources can change quickly, impacting the storm development.
Neural control of lexical tone production in human laryngeal motor cortex
Authors: Lu Junfeng , Li Yuanning , Zhao Zehao , Liu Yan , Zhu Yanming , Mao Ying , Wu Jinsong , Chang Edward F. 
Published: October 2023

AbstractIn tonal languages, which are spoken by nearly one-third of the world’s population, speakers precisely control the tension of vocal folds in the larynx to modulate pitch in order to distinguish words with completely different meanings. The specific pitch trajectories for a given tonal language are called lexical tones. Here, we used high-density direct cortical recordings to determine the neural basis of lexical tone production in native Mandarin-speaking participants. We found that instead of a tone category-selective coding, local populations in the bilateral laryngeal motor cortex (LMC) encode articulatory kinematic information to generate the pitch dynamics of lexical tones. Using a computational model of tone production, we discovered two distinct patterns of population activity in LMC commanding pitch rising and lowering. Finally, we showed that direct electrocortical stimulation of different local populations in LMC evoked pitch rising and lowering during tone production, respectively. Together, these results reveal the neural basis of vocal pitch control of lexical tones in tonal languages.
Additive manufacturing of alloys with programmable microstructure and properties
Authors: Gao Shubo , Li Zhi , Van Petegem Steven , Ge Junyu , Goel Sneha , Vas Joseph Vimal , Luzin Vladimir , Hu Zhiheng , Seet Hang Li , Sanchez Dario Ferreira , Van Swygenhoven Helena , Gao Huajian , Seita Matteo 
Published: October 2023

AbstractIn metallurgy, mechanical deformation is essential to engineer the microstructure of metals and to tailor their mechanical properties. However, this practice is inapplicable to near-net-shape metal parts produced by additive manufacturing (AM), since it would irremediably compromise their carefully designed geometries. In this work, we show how to circumvent this limitation by controlling the dislocation density and thermal stability of a steel alloy produced by laser powder bed fusion (LPBF) technology. We show that by manipulating the alloy’s solidification structure, we can ‘program’ recrystallization upon heat treatment without using mechanical deformation. When employed site-specifically, our strategy enables designing and creating complex microstructure architectures that combine recrystallized and non-recrystallized regions with different microstructural features and properties. We show how this heterogeneity may be conducive to materials with superior performance compared to those with monolithic microstructure. Our work inspires the design of high-performance metal parts with artificially engineered microstructures by AM.
Thermal dependence of the hydrated proton and optimal proton transfer in the protonated water hexamer
Authors: Mouhat Félix , Peria Matteo , Morresi Tommaso , Vuilleumier Rodolphe , Saitta Antonino Marco , Casula Michele 
Published: October 2023

AbstractWater is a key ingredient for life and plays a central role as solvent in many biochemical reactions. However, the intrinsically quantum nature of the hydrogen nucleus, revealing itself in a large variety of physical manifestations, including proton transfer, gives rise to unexpected phenomena whose description is still elusive. Here we study, by a combination of state-of-the-art quantum Monte Carlo methods and path-integral molecular dynamics, the structure and hydrogen-bond dynamics of the protonated water hexamer, the fundamental unit for the hydrated proton. We report a remarkably low thermal expansion of the hydrogen bond from zero temperature up to 300 K, owing to the presence of short-Zundel configurations, characterised by proton delocalisation and favoured by the synergy of nuclear quantum effects and thermal activation. The hydrogen bond strength progressively weakens above 300 K, when localised Eigen-like configurations become relevant. Our analysis, supported by the instanton statistics of shuttling protons, reveals that the near-room-temperature range from 250 K to 300 K is optimal for proton transfer in the protonated water hexamer.
Exploring decarbonization pathways for USA passenger and freight mobility
Authors: Hoehne Christopher , Muratori Matteo , Jadun Paige , Bush Brian , Yip Arthur , Ledna Catherine , Vimmerstedt Laura , Podkaminer Kara , Ma Ookie 
Published: October 2023

AbstractPassenger and freight travel account for 28% of U.S. greenhouse gas (GHG) emissions today. We explore pathways to reduce transportation emissions using NREL’s TEMPO model under bounding assumptions on future travel behavior, technology advancement, and policies. Results show diverse routes to 80% or more well-to-wheel GHG reductions by 2050. Rapid adoption of zero-emission vehicles coupled with a clean electric grid is essential for deep decarbonization; in the median scenario, zero-emission vehicle sales reach 89% for passenger light-duty and 69% for freight trucks by 2030 and 100% sales for both by 2040. Up to 3,000 terawatt-hours of electricity could be needed in 2050 to power plug-in electric vehicles. Increased sustainable biofuel usage is also essential for decarbonizing aviation (10–42 billion gallons needed in 2050) and to support legacy vehicles during the transition. Managing travel demand growth can ease this transition by reducing the need for clean electricity and sustainable fuels.
Global climate forcing on late Miocene establishment of the Pampean aeolian system in South America
Authors: Stubbins Blake , Leier Andrew L. , Barbeau David L. , Pullen Alex , Abell Jordan T. , Nie Junsheng , Zárate Marcelo A. , Fidler Mary Kate 
Published: October 2023

AbstractWind-blown dust from southern South America links the terrestrial, marine, atmospheric, and biological components of Earth’s climate system. The Pampas of central Argentina (~33°–39° S) contain a Miocene to Holocene aeolian record that spans an important interval of global cooling. Upper Miocene sediment provenance based on n = 3299 detrital-zircon U-Pb ages is consistent with the provenance of Pleistocene–Holocene deposits, indicating the Pampas are the site of a long-lived fluvial-aeolian system that has been operating since the late Miocene. Here, we show the establishment of aeolian sedimentation in the Pampas coincided with late Miocene cooling. These findings, combined with those from the Chinese Loess Plateau (~33°–39° N) underscore: (1) the role of fluvial transport in the development and maintenance of temporally persistent mid-latitude loess provinces; and (2) a global-climate forcing mechanism behind the establishment of large mid-latitude loess provinces during the late Miocene.
Optogenetic control of YAP reveals a dynamic communication code for stem cell fate and proliferation
Authors: Meyer Kirstin , Lammers Nicholas C. , Bugaj Lukasz J. , Garcia Hernan G. , Weiner Orion D. 
Published: October 2023

AbstractYAP is a transcriptional regulator that controls pluripotency, cell fate, and proliferation. How cells ensure the selective activation of YAP effector genes is unknown. This knowledge is essential to rationally control cellular decision-making. Here we leverage optogenetics, live-imaging of transcription, and cell fate analysis to understand and control gene activation and cell behavior. We reveal that cells decode the steady-state concentrations and timing of YAP activation to control proliferation, cell fate, and expression of the pluripotency regulators Oct4 and Nanog. While oscillatory YAP inputs induce Oct4 expression and proliferation optimally at frequencies that mimic native dynamics, cellular differentiation requires persistently low YAP levels. We identify the molecular logic of the Oct4 dynamic decoder, which acts through an adaptive change sensor. Our work reveals how YAP levels and dynamics enable multiplexing of information transmission for the regulation of developmental decision-making and establishes a platform for the rational control of these behaviors.
Fading regulation of diurnal temperature ranges on drought-induced growth loss for drought-tolerant tree species
Authors: Zhang Xianliang , Rademacher Tim , Liu Hongyan , Wang Lu , Manzanedo Rubén D. 
Published: October 2023

AbstractWarming-induced droughts caused tree growth loss across the globe, leading to substantial carbon loss to the atmosphere. Drought-induced growth loss, however, can be regulated by changes in diurnal temperature ranges. Here, we investigated long term radial growth responses of 23 widespread distributed tree species from 2327 sites over the world and found that species’ drought tolerances were significantly and positively correlated with diurnal temperature range-growth loss relationships for the period 1901-1940. Since 1940, this relationship has continued to fade, likely due to asymmetric day and night warming trends and the species’ ability to deal with them. The alleviation of reduced diurnal temperature ranges on drought-induced growth loss was mainly found for drought resistant tree species. Overall, our results highlight the need to carefully consider diurnal temperature ranges and species-specific responses to daytime and nighttime warming to explore tree growth responses to current and future warmer and drier climates.
Leveraging data from the Genomes-to-Fields Initiative to investigate genotype-by-environment interactions in maize in North America
Authors: Lopez-Cruz Marco , Aguate Fernando M. , Washburn Jacob D. , de Leon Natalia , Kaeppler Shawn M. , Lima Dayane Cristina , Tan Ruijuan , Thompson Addie , De La Bretonne Laurence Willard , de los Campos Gustavo 
Published: October 2023

AbstractGenotype-by-environment (G×E) interactions can significantly affect crop performance and stability. Investigating G×E requires extensive data sets with diverse cultivars tested over multiple locations and years. The Genomes-to-Fields (G2F) Initiative has tested maize hybrids in more than 130 year-locations in North America since 2014. Here, we curate and expand this data set by generating environmental covariates (using a crop model) for each of the trials. The resulting data set includes DNA genotypes and environmental data linked to more than 70,000 phenotypic records of grain yield and flowering traits for more than 4000 hybrids. We show how this valuable data set can serve as a benchmark in agricultural modeling and prediction, paving the way for countless G×E investigations in maize. We use multivariate analyses to characterize the data set’s genetic and environmental structure, study the association of key environmental factors with traits, and provide benchmarks using genomic prediction models.
Assessing the size and uncertainty of remaining carbon budgets
Authors: Lamboll Robin D. , Nicholls Zebedee R. J. , Smith Christopher J. , Kikstra Jarmo S. , Byers Edward , Rogelj Joeri 
Published: October 2023

AbstractThe remaining carbon budget (RCB), the net amount of CO2 humans can still emit without exceeding a chosen global warming limit, is often used to evaluate political action against the goals of the Paris Agreement. RCB estimates for 1.5 °C are small, and minor changes in their calculation can therefore result in large relative adjustments. Here we evaluate recent RCB assessments by the IPCC and present more recent data, calculation refinements and robustness checks that increase confidence in them. We conclude that the RCB for a 50% chance of keeping warming to 1.5 °C is around 250 GtCO2 as of January 2023, equal to around six years of current CO2 emissions. For a 50% chance of 2 °C the RCB is around 1,200 GtCO2. Key uncertainties affecting RCB estimates are the contribution of non-CO2 emissions, which depends on socioeconomic projections as much as on geophysical uncertainty, and potential warming after net zero CO2.
Spatial communication systems across languages reflect universal action constraints
Authors: Coventry Kenny R. , Gudde Harmen B. , Diessel Holger , Collier Jacqueline , Guijarro-Fuentes Pedro , Vulchanova Mila , Vulchanov Valentin , Todisco Emanuela , Reile Maria , Breunesse Merlijn , Plado Helen , Bohnemeyer Juergen , Bsili Raed , Caldano Michela , Dekova Rositsa , Donelson Katharine , Forker Diana , Park Yesol , Pathak Lekhnath Sharma , Peeters David , Pizzuto Gabriella , Serhan Baris , Apse Linda , Hesse Florian , Hoang Linh , Hoang Phuong , Igari Yoko , Kapiley Keerthana , Haupt-Khutsishvili Tamar , Kolding Sara , Priiki Katri , Mačiukaitytė Ieva , Mohite Vaisnavi , Nahkola Tiina , Tsoi Sum Yi , Williams Stefan , Yasuda Shunei , Cangelosi Angelo , Duñabeitia Jon Andoni , Mishra Ramesh Kumar , Rocca Roberta , Šķilters Jurģis , Wallentin Mikkel , Žilinskaitė-Šinkūnienė Eglė , Incel Ozlem Durmaz 
Published: October 2023

AbstractThe extent to which languages share properties reflecting the non-linguistic constraints of the speakers who speak them is key to the debate regarding the relationship between language and cognition. A critical case is spatial communication, where it has been argued that semantic universals should exist, if anywhere. Here, using an experimental paradigm able to separate variation within a language from variation between languages, we tested the use of spatial demonstratives—the most fundamental and frequent spatial terms across languages. In n = 874 speakers across 29 languages, we show that speakers of all tested languages use spatial demonstratives as a function of being able to reach or act on an object being referred to. In some languages, the position of the addressee is also relevant in selecting between demonstrative forms. Commonalities and differences across languages in spatial communication can be understood in terms of universal constraints on action shaping spatial language and cognition.
Self-regulating arousal via pupil-based biofeedback
Authors: Meissner Sarah Nadine , Bächinger Marc , Kikkert Sanne , Imhof Jenny , Missura Silvia , Carro Dominguez Manuel , Wenderoth Nicole 
Published: October 2023

AbstractThe brain’s arousal state is controlled by several neuromodulatory nuclei known to substantially influence cognition and mental well-being. Here we investigate whether human participants can gain volitional control of their arousal state using a pupil-based biofeedback approach. Our approach inverts a mechanism suggested by previous literature that links activity of the locus coeruleus, one of the key regulators of central arousal and pupil dynamics. We show that pupil-based biofeedback enables participants to acquire volitional control of pupil size. Applying pupil self-regulation systematically modulates activity of the locus coeruleus and other brainstem structures involved in arousal control. Furthermore, it modulates cardiovascular measures such as heart rate, and behavioural and psychophysiological responses during an oddball task. We provide evidence that pupil-based biofeedback makes the brain’s arousal system accessible to volitional control, a finding that has tremendous potential for translation to behavioural and clinical applications across various domains, including stress-related and anxiety disorders.
A systematic review and meta-analysis of the global prevalence and determinants of COVID-19 vaccine acceptance and uptake in people living with HIV
Authors: Sulaiman Sahabi Kabir , Musa Muhammad Sale , Tsiga-Ahmed Fatimah Isma’il , Sulaiman Abdulwahab Kabir , Bako Abdulaziz Tijjani 
Published: October 2023

AbstractPeople living with HIV (PLHIV) are at higher risk of poor outcomes of SARS-CoV-2 infection. Here we report the pooled prevalence of COVID-19 vaccine acceptance/uptake and determinants among this vulnerable population of PLHIV based on a systematic review and meta-analysis of studies published by 25 August 2023. Among the 54 included studies (N = 167,485 participants), 53 (N = 166,455) provided data on vaccine acceptance rate, while 27 (N = 150,926) provided uptake data. The global prevalences of COVID-19 vaccine acceptance and uptake were 67.0% and 56.6%, respectively. Acceptance and uptake rates were 86.6% and 90.1% for the European Region, 74.9% and 71.6% for the Region of the Americas, 62.3% and 78.9% for the South-East Asian Region, 64.6% and 19.3% for the Eastern Mediterranean Region, 58.0% and 35.5% for the African Region, and 57.4% and 44.0% for the Western Pacific Region. The acceptance rate increased from 65.9% in 2020 to 71.0% in 2022, and the uptake rate increased from 55.9% in 2021 to 58.1% in 2022. Men, PLHIV aged ≥40 years and those who had recently received the influenza vaccine were more likely to accept and receive the COVID-19 vaccine. Factors associated with lower uptake included Black race, other races (Latinx/Hispanic/mixed race), low education level and being unemployed. Vaccine-related factors associated with higher acceptance included belief in vaccine effectiveness, vaccine trust, perceived high susceptibility to SARS-CoV-2 infection and fear of potential COVID-19 effect in PLHIV. Sustained efforts and targeted interventions are needed to reduce regional disparities in COVID-19 vaccine uptake among PLHIV.
Time lag effect on malaria transmission dynamics in an Amazonian Colombian municipality and importance for early warning systems
Authors: Gonzalez-Daza William , Vivero-Gómez Rafael Jose , Altamiranda-Saavedra Mariano , Muylaert Renata L. , Landeiro Victor Lemes 
Published: October 2023

AbstractMalaria remains a significant public health problem worldwide, particularly in low-income regions with limited access to healthcare. Despite the use of antimalarial drugs, transmission remains an issue in Colombia, especially among indigenous populations in remote areas. In this study, we used an SIR Ross MacDonald model that considered land use change, temperature, and precipitation to analyze eco epidemiological parameters and the impact of time lags on malaria transmission in La Pedrera—Amazonas municipality. We found changes in land use between 2007 and 2020, with increases in forested areas, urban infrastructure and water edges resulting in a constant increase in mosquito carrying capacity. Temperature and precipitation variables exhibited a fluctuating pattern that corresponded to rainy and dry seasons, respectively and a marked influence of the El Niño climatic phenomenon. Our findings suggest that elevated precipitation and temperature increase malaria infection risk in the following 2 months. The risk is influenced by the secondary vegetation and urban infrastructure near primary forest formation or water body edges. These results may help public health officials and policymakers develop effective malaria control strategies by monitoring precipitation, temperature, and land use variables to flag high-risk areas and critical periods, considering the time lag effect.
Comparative effectiveness of two intravenous immunoglobulin products in children with Kawasaki disease, a nationwide cohort study
Authors: Kuo Ni-Chun , Lin Ching-Heng , Lin Ming-Chih 
Published: October 2023

AbstractKawasaki Disease (KD) is the most common acquired pediatric heart disease in the developed world. Rapid infusion of high-dose intravenous immunoglobulin is the standard therapy. Different manufacturing processes of IVIG may influence their efficacy. This study aims to conduct a head to head comparison of two IVIGs, TBSF and Privigen, from a nationwide perspective. The main data source was the National Health Insurance Research Database (NHIRD) of Taiwan. A total of 3368 KD cases involving children under 2 years of age were enrolled from January 2015 to November 2020. The primary endpoint was IVIG resistance, which we defined as the total amount exceeding 26 g in one admission. The secondary endpoints encompassed two distinct criteria: coronary involvement, which was defined as the prolonged use of aspirin or anti-coagulation agents between 180 and 360 days after the index date, and recurrence, which was defined as readmission for IVIG therapy occurring more than 30 days after previous KD index day and continuing until the end of the follow-up period. Privigen demonstrated a lower IVIG resistance rate at 9.4% in comparison to TBSF, which exhibited a rate of 9.7% (odds ratio 0.72, 95% CI 0.52–0.99). Privigen had a lower odds of coronary involvement (odds ratio 0.38, 95% CI 0.18–0.82). There is no difference in recurrence rate (odds ratio 0.60, 95% CI 0.22–1.68). Privigen might have a lower rate of IVIG resistance and reduced coronary artery involvement. The discrepancy may be due to the concentration, the stabilizers, or the source of plasma. Further investigation is needed to compare the effectiveness of different IVIGs in the large randomized controlled clinical trial.