bluuebunny/crossref_metadata_2025_split huggingface dataset:
Prenatal magnetic resonance imaging in Gomez‐Lopez‐Hernandez syndrome and review of the literature
Authors: Tan Tiong Yang , McGillivray George , Goergen Stacy K. , White Susan M. 
Published: September 2005

AbstractGomez‐Lopez‐Hernandez syndrome, or cerebello‐trigeminal‐dermal dysplasia (OMIM#601853), is a rare syndrome comprising cerebellar abnormalities, parieto‐occipital alopecia, trigeminal nerve anesthesia, intellectual impairment, craniosynostosis, short stature, and craniofacial anomalies. It has been reported in ten patients, five of whom are Brazilian. Rhombencephalosynapsis is a rare sporadic cerebellar anomaly comprising fusion of the cerebellar hemispheres with agenesis of the cerebellar vermis. Rhombencephalosynapsis is a constant feature of Gomez‐Lopez‐Hernandez syndrome. We present the clinical and imaging findings of a Caucasian male infant with Gomez‐Lopez‐Hernandez syndrome. Rhombencephalosynapsis was diagnosed with fetal magnetic resonance imaging (MRI) after an abnormally shaped small cerebellum was detected by antenatal ultrasound (US). Gomez‐Lopez‐Hernandez syndrome was diagnosed at age 6 weeks when parietal alopecia was noted. Prenatal imaging studies of Gomez‐Lopez‐Hernandez syndrome have not been published before. When rhombencephalosynapsis is diagnosed prenatally, the clinical features of Gomez‐Lopez‐Hernandez syndrome should be sought at postnatal review. Gomez‐Lopez‐Hernandez syndrome and isolated rhombencephalosynapsis may have a common etiology. © 2005 Wiley‐Liss, Inc.
Simulation of oxygen carrier mediated oxygen transport to C3A hepatoma cells housed within a hollow fiber bioreactor
Authors: Sullivan Jesse P. , Gordon Jason E. , Palmer Andre F. 
Published: September 2005

AbstractA priori knowledge of the dissolved oxygen (O2) concentration profile within a hepatic hollow fiber (HF) bioreactor is important in developing an effective bioartificial liver assist device (BLAD). O2 provision is limiting within HF bioreactors and we hypothesize that supplementing a hepatic HF bioreactor's circulating media with bovine red blood cells (bRBCs), which function as an O2 carrier, will improve oxygenation. The dissolved O2 concentration profile within a single HF (lumen, membrane, and representative extra capillary space (ECS)) was modeled with the finite element method, and compared to experimentally measured data obtained on an actual HF bioreactor with the same dimensions housing C3A hepatoma cells. Our results (experimental and modeling) indicate bRBC supplementation of the circulating media leads to an increase in O2 consumed by C3A cells. Under certain experimental conditions (pO2,IN = 95 mmHg, Q = 8.30 mL/min), the addition of bRBCs at 5% of the average in vivo human red blood cell concentration (% hRBC) results in ∼50% increase in the O2 consumption rate (OCR). By simply adjusting the operating conditions (pO2,IN = 25 mmHg, Q = 1.77 mL/min) and increasing bRBC concentration to 25% hRBC the OCR increase is ∼10‐fold. However, the improved O2 concentration profile experienced by the C3A cells could not duplicate the full range of in vivo O2 tensions (25–70 mmHg) typically experienced within the liver sinusoid with this particular HF bioreactor. Nonetheless, we demonstrate that the O2 transport model accurately predicts O2 consumption within a HF bioreactor, thus setting up the modeling framework for improving the design of future hepatic HF bioreactors. © 2005 Wiley Periodicals, Inc.
Synthetic Applications of (Me3SiNSN)2E (E: S, Se) in Chalcogen‐Nitrogen Chemistry: Formation and Structural Characterization of Cl2TeESN2 (E: S, Se) and [PPh4]2 [Pd2(μ‐Se2N2S)X4] (X: Cl, Br).
Authors: Konu Jari , Ahlgren Markku , Aucott Stephen M. , Chivers Tristram , Dale Sophie H. , Elsegood Mark R. J. , Holmes Kathryn E. , James Sarah L. M. , Kelly Paul F. , Laitinen Risto S. 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
One‐Pot Synthesis of E‐Alkylidene Derivatives of 3H‐Furan‐2‐ones from 4‐Pentynoic Acid and Aldehyde.
Authors: Lim Sung‐Gon , Kwon Bong‐Il , Choi Moon‐Gun , Jun Chul‐Ho 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Stepwise Cross‐Couplings of a Dibromo‐γ‐methylenebutenolide as an Access to Z‐Configured α‐Alkenyl‐γ‐alkylidenebutenolides. Straightforward Synthesis of the Antibiotic Lissoclinolide.
Authors: Sorg Achim , Blank Frederik , Brueckner Reinhard 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Asymmetric Synthesis of Dihydrofurans via Rh(II)‐Catalyzed Cyclopropanation—Rearrangement of Enol Ethers with 1‐(Silanyloxy)vinyl Diazoacetates.
Authors: Mueller Paul , Bernardinelli Gerald , Allenbach Yves F. , Ferri Maria , Grass Stephane 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A Novel Route to the 5,6‐Dihydro‐4H‐thieno[3,2‐b]pyrrol‐5‐one Ring System Involving an Intermediate Substituted‐Thiophene Synthesis.
Authors: Hu Shuanghua , Huang Yazhong , Poss Michael A. , Gentles Robert G. 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Catalyst‐Free Microwave‐Assisted Synthesis of α‐Aminophosphonates in a Three‐Component System: R1C(O)R2—(EtO)2P (O)H—RNH2.
Authors: Kabachnik Maria M. , Zobnina Elena V. , Beletskaya Irina P. 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
A “User‐Friendly” Chemical Approach Towards Paramagnetic Cobalt Phosphide Hollow Structures: Preparation, Characterization, and Formation Mechanism of Co2P Hollow Spheres and Tubes.
Authors: Hou Hongwei , Peng Qi , Zhang Shuyuan , Guo Qixun , Xie Yi 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Anisotropic Metal Nanoparticles: Synthesis, Assembly, and Optical Applications
Authors: Murphy Catherine J. , Sau Tapan K. , Gole Anand M. , Orendorff Christopher J. , Gao Jinxin , Gou Linfeng , Hunyadi Simona E. , Li Tan 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
C—C Coupling and C—H Bond Activation Reactions of Cyclopentadienyl—Osmium Compounds: The Rich and Varied Chemistry of Os(η5‐C5H5)Cl (PiPr3)2 and Its Major Derivatives
Authors: Esteruelas Miguel A. , Lopez Ana M. 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Mastering the Challenges of Catalyst Screening in High‐Throughput Experimentation for Heterogeneously Catalyzed Gas‐Phase Reactions
Authors: Schunk Stephan A. , Demuth Dirk , Cross Alexander , Gerlach Olga , Haas Alfred , Klein Jens , Newsam John M. , Sundermann Andreas , Stichert Wolfram , Strehlau Wolfgang , et al. et al. 
Published: September 2005

AbstractFor Abstract see ChemInform Abstract in Full Text.
Axillary disease recurrence after sentinel lymph node dissection for breast carcinoma
Authors: Swenson Karen K. , Mahipal Amit , Nissen Mary J. , Tuttle Todd M. , Heaton Keith , Lally Robin M. , Spomer Amy , Lee Martin W. 
Published: September 2005

AbstractBACKGROUNDSurgical recommendation for early‐stage breast carcinoma includes removal of the primary breast tumor and evaluation of the axillary lymph nodes on the ipsilateral side. Sentinel lymph node dissection (SLND) is increasingly being used to evaluate axillary lymph nodes in clinically lymph node negative patients as an alternative to axillary lymph node dissection (ALND). Results from SLND are highly predictive of metastatic involvement in the axilla, and are associated with fewer side effects. However, the greatest concern with SLND alone is the potential for a higher rate of axillary lymph node recurrence. The purpose of the current study was to review data collected on 700 consecutive patients with early‐stage breast carcinoma who underwent SLND without concomitant ALND.METHODSA retrospective study was conducted using the oncology registry at Park Nicollet Health Services (Minneapolis, MN). Consecutive breast carcinoma cases with SLND only for axillary surgery, from January 28, 1999 to December 31, 2003, were included in the study. During this period, 700 patients with breast carcinoma were identified who had SLND alone. Fifty‐two patients were excluded from the analysis because they had ductal carcinoma in situ.RESULTSWith a median follow‐up of 33 months (range, 2‐73 mos), axillary lymph node recurrence occurred in 4 of 647 (0.62%) patients overall. In these 4 patients, the axillary lymph node recurrences were isolated to the axillary lymph nodes and amenable to surgery.CONCLUSIONSData from the current study showed that axillary lymph node recurrence after SLND occurred very infrequently in early‐stage breast carcinoma, and these results were comparable to other studies. Cancer 2005. © 2005 American Cancer Society.
Scheduling communication in multithreaded programs: experimental results
Authors: Gomez Juan Carlos , Rego Vernon , Sunderam V. S. 
Published: September 2005

AbstractWhen the critical path of a communication session between end points includes the actions of operating system kernels, there are attendant overheads. Along with other factors, such as functionality and flexibility, such overheads motivate and favor the implementation of communication protocols in user space. When implemented with threads, such protocols may hold the key to optimal communication performance and functionality. Based on implementations of reliable user‐space protocols supported by a threads framework, we focus on our experiences with internal threads' scheduling techniques and their potential impact on performance. We present scheduling strategies that enable threads to do both application‐level and communication‐related processing. With experiments performed on a Sun SPARC‐5 LAN environment, we show how different scheduling strategies yield different levels of application‐processing efficiency, communication latency and packet‐loss. This work forms part of a larger study on the implementation of multiple thread‐based protocols in a single address space, and the benefits of coupling protocols with applications. Copyright © 2005 John Wiley & Sons, Ltd.
Parallel iterative multilevel solution of mixed finite element systems for scalar equations
Authors: Chugunov V. , Svyatski D. , Tyrtyshnikov E. , Vassilevski Yu. 
Published: September 2005

AbstractA combination of several contemporary techniques is used for the efficient parallel solution of the mixed finite element systems on locally refined Grids. Implementation experience and numerical results are reported. Copyright © 2005 John Wiley & Sons, Ltd.
Learning with an active e‐course in the Knowledge Grid environment
Authors: Zhuge Hai , Li Yanyan 
Published: September 2005

AbstractAn active e‐course is an open, self‐representable and self‐organizable media mechanism. Its kernel idea is to organize learning materials in a concept space rather than in a page space. The tailored content and flexible structure of the e‐courses can be dynamically formed to cater for different learners with different backgrounds, capabilities and expectations, at different times and venues. The active e‐course can also assess learners' learning performances and give appropriate suggestions to guide them in further learning. An authoring tool for constructing course ontology and a system prototype have been developed to support an active e‐course, enabling a learner‐centred, highly interactive and adaptive learning approach. The results of an empirical study show that the system can help enhance the effectiveness and efficiency of learning. Copyright © 2005 John Wiley & Sons, Ltd.
Enantio‐ and Diastereoselective Synthesis of Highly Substituted Acylcyclopropanes from Homoaldol Products by Stereospecific Homoallylic Cyclization
Authors: Kalkofen Rainer , Brandau Sven , Ünaldi Seda , Fröhlich Roland , Hoppe Dieter 
Published: September 2005

AbstractHighly enantioenriched 4‐hydroxy‐1‐alkenyl N,N‐diisopropylcarbamates, easily available by asymmetric homoaldol reaction, cyclize by treatment with sodium hydride to form (1r,2t,3t)‐configured 1‐acylcyclopropanes with high diastereoselectivity. The decisive steps are the migration of the N,N‐diisopropylcarbamoyl group onto the alkoxide oxygen atom, followed by an intramolecular homoallylic substitution reaction of the intermediate γ‐carbamoyloxy enolate with inversion of the configuration at the γ‐C atom. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005)
Cover Picture: Improving the Properties of Organic Dyes by Molecular Encapsulation (Eur. J. Org. Chem. 19/2005)
Authors: Arunkumar Easwaran , Forbes Christopher C. , Smith Bradley D. 
Published: September 2005

AbstractThe cover picture shows some of the supramolecular encapsulation strategies that have been used to improve the photophysical and photochemical properties of organic dyes. The work is summarized in the microreview by E. Arunkurmar, C. C. Forbes, and D. Smith on p. 4051 ff.
Telling truth from lie in individual subjects with fast event‐related fMRI
Authors: Langleben Daniel D. , Loughead James W. , Bilker Warren B. , Ruparel Kosha , Childress Anna Rose , Busch Samantha I. , Gur Ruben C. 
Published: September 2005

AbstractDeception is a clinically important behavior with poorly understood neurobiological correlates. Published functional MRI (fMRI) data on the brain activity during deception indicates that, on a multisubject group level, lie is distinguished from truth by increased prefrontal and parietal activity. These findings are theoretically important; however, their applied value will be determined by the accuracy of the discrimination between single deceptive and truthful responses in individual subjects. This study presents the first quantitative estimate of the accuracy of fMRI in conjunction with a formal forced‐choice paradigm in detecting deception in individual subjects. We used a paradigm balancing the salience of the target cues to elicit deceptive and truthful responses and determined the accuracy of this model in the classification of single lie and truth events. The relative salience of the task cues affected the net activation associated with lie in the superior medial and inferolateral prefrontal cortices. Lie was discriminated from truth on a single‐event level with an accuracy of 78%, while the predictive ability expressed as the area under the curve (AUC) of the receiver operator characteristic curve (ROC) was 85%. Our findings confirm that fMRI, in conjunction with a carefully controlled query procedure, could be used to detect deception in individual subjects. Salience of the task cues is a potential confounding factor in the fMRI pattern attributed to deception in forced choice deception paradigms. Hum Brain Mapp, 2005. © 2005 Wiley‐Liss, Inc.
Induced theta oscillations mediate large‐scale synchrony with mediotemporal areas during recollection in humans
Authors: Guderian Sebastian , Düzel Emrah 
Published: September 2005

AbstractOne functional aspect of theta oscillations that recent studies have begun to explore in humans is their role for the recollection of personal events. A specific role of theta for recollection but not for stimulus‐familiarity would support links between cortical theta oscillations and hippocampal functioning, given that the hippocampus seems to be more critical for recollection than for stimulus‐familiarity. During recollection, theta oscillations might mediate a dynamic link between hippocampal and neocortical areas, thereby allowing to recruit and bind distributed cortical representations. We recorded theta oscillations using whole‐head magnetoencephalography while nine healthy subjects made recognition memory judgments on previously studied and unstudied pictures of faces. For each recognized face, subjects indicated whether they also recollected the background image in front of which that face was studied. Theta oscillations were higher in amplitude during recollection than during recognition in the absence of accurate memory for the background. These theta oscillations were induced in nature, meaning that they showed considerable phase variability from trial to trial. To nevertheless extract the field distribution of coherent theta oscillations from single trials, we calculated phase differences between sensor pairs at each time point of each single trial. This field information was used to localize the brain sources of synchronized theta‐generators. The results suggest that recollection is associated with induced activity increase in a distributed synchronous theta network, including prefrontal, mediotemporal, and visual areas. These findings are compatible with the notion that theta oscillations are related to the binding of distributed cortical representations during recollection. © 2005 Wiley‐Liss, Inc.
Maternal medication use and the risk of brain tumors in the offspring: The SEARCH international case‐control study
Authors: Cardy Amanda H. , Little Julian , McKean‐Cowdin Roberta , Lijinsky William , Choi N. Won , Cordier Sylvanie , Filippini Graziella , Holly Elizabeth A. , Lubin Flora , McCredie Margaret , Mueller Beth A. , Peris‐Bonet Raphael , Arslan Annie , Preston‐Martin Susan 
Published: September 2005

AbstractN‐nitroso compounds (NOC) have been associated with carcinogenesis in a wide range of species, including humans. There is strong experimental data showing that nitrosamides (R1NNO·COR2), a type of NOC, are potent neuro‐carcinogens when administered transplacentally. Some medications are a concentrated source of amides or amines, which in the presence of nitrites under normal acidic conditions of the stomach can form NOC. Therefore, these compounds, when ingested by women during pregnancy, may be important risk factors for tumors of the central nervous system in the offspring. The aim of the present study was to test the association between maternal use of medications that contain nitrosatable amines or amides and risk of primary childhood brain tumors (CBT). A case‐control study was conducted, which included 1,218 cases and 2,223 population controls, recruited from 9 centers across North America, Europe and Australia. Analysis was conducted for all participants combined, by tumor type (astroglial, primitive neuroectodermal tumors and other glioma), and by age at diagnosis (≤5 years; >5 years). There were no significant associations between maternal intake of medication containing nitrosatable amines or amides and CBT, for all participants combined and after stratification by age at diagnosis and histological subtype. This is the largest case‐control study of CBT and maternal medications to date. Our data provide little support for an association between maternal use of medications that may form NOC and subsequent development of CBT in the offspring. © 2005 Wiley‐Liss, Inc.
Obesity, hormone therapy, estrogen metabolism and risk of postmenopausal breast cancer
Authors: Modugno Francesmary , Kip Kevin E. , Cochrane Barbara , Kuller Lewis , Klug Thomas L. , Rohan Thomas E. , Chlebowski Rowan T. , Lasser Norman , Stefanick Marcia L. 
Published: September 2005

AbstractHormone therapy (HT) and body mass index (BMI) have been associated with postmenopausal breast cancer. Because estrogen metabolism may affect breast cancer risk and can be altered by weight and HT, it might play a role in the HT–BMI–breast cancer associations. We undertook a nested case‐control study within the Observational Study of the Women's Health Initiative. Baseline levels of 2‐ and 16α‐hydroxy estrone (2‐OHE1 and 16α‐OHE1) were measured in 200 women who developed breast cancer during follow‐up and 200 healthy controls matched to cases by ethnicity, enrollment date, clinic site, type of HT and years since menopause. Wilcoxon nonparametric tests were used to compare estrogen metabolite levels between cases and controls. Conditional logistic regression was used to assess the relationship between BMI, estrogen metabolites and breast cancer risk. 16α‐OHE1 levels were modestly but significantly higher in HT users among cases (median 356 pg/ml vs. 315 pg/ml) and controls (354 pg/ml vs. 298 pg/ml). 2‐OHE1 levels were substantially and significantly higher in HT users among cases (369 pg/ml vs. 125 pg/ml) and controls (347 pg/ml vs. 134 pg/ml). For non‐HT users only, greater BMI and higher 16α‐OHE1 levels were individually and jointly associated with increased breast cancer risk (OR for women with high BMI and high 16α‐OHE1 compared to those with low BMI and low 16α‐OHE1 = 3.51, 95% CI = 1.34–9.16). No associations between BMI, estrogen metabolism and breast cancer risk were found for HT users. Estrogen metabolism differs according to both BMI and HT use, potentially explaining the interaction between BMI and HT in relation to breast cancer risk. © 2005 Wiley‐Liss, Inc.
Fabrication of microporous thermoplastic polyurethane for use as small‐diameter vascular graft material. I. Phase‐inversion method
Authors: Khorasani M. T. , Shorgashti S. 
Published: September 2005

AbstractFabrication conditions of microporous thermoplastic polyurethane to be used in small‐diameter vascular grafts are studied. Porosity variations due to various factors such as concentration of PU solution, composition of coagulation bath, effect of coagulant temperature, and effect of dissolved air in PU solution are discussed. The liquid–liquid phase‐inversion process used for preparation of PU films and the mechanism for the formation of microporous films are discussed. Surface and cross‐section morphologies of PU films are studied with the use of scanning electron microscopy (SEM), and porosity value and mechanical strength of PU films are also determined. SEM photomicrographs show that PU films prepared in an alcoholic coagulant have uniform porous structure compared to films prepared in water coagulant. Increasing the polymer concentration and coagulant temperature (>23°C) decreases the macrovoid formation, as seen in cross sections of PU films. This enhances the tensile modulus of PU films. By using this process adjustment may be made on the morphology and compliance, as they are important factors in design and fabrication of small‐diameter vascular grafts. © 2005 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2006
Teaching fidelity
Authors: Pittman Frank S. , Wagers Tina Pittman 
Published: September 2005

AbstractWorking therapeutically with individuals or couples either following an affair or prior to its occurrence requires teaching them about risks to monogamy and the challenges of recovering from infidelity. Risks to monogamy include cultural myths about both infidelity and marriage that may be shared not only by lay persons, but also by their ill‐informed therapists. Exacerbating risks to fidelity are physiological components of emotional and physical attraction that contribute to cognitive and affective disorientation. Therapists can promote fidelity and recovery from infidelity by attending to the fundamental tasks of modeling compassion, debunking myths regarding infidelity, confronting individuals with their own choices, promoting emotional closeness, and helping individuals to understand both their own and their partner's learned attitudes that distract them from maintaining a faithful marriage. Several cases illustrate these fundamental therapeutic tasks. © 2005 Wiley Periodicals, Inc. J Clin Psychol/In Session 61: 1407–1419, 2005.
Treating infidelity in same‐sex couples
Authors: Martell Christopher R. , Prince Stacey E. 
Published: September 2005

AbstractPsychotherapy with same‐sex couples does not differ markedly from standard couple therapies; this is also true for treating couples facing infidelity. However, same‐sex couples often design their relationships differently, without tradition and formal marital contracts to prescribe behavior. Based on clinical experience and the empirical research, this article addresses the differing norms involved in affirmatively treating infidelity in gay and lesbian couples within the framework of integrative behavioral couple therapy (IBCT). Two cases illustrate the process and outcome of IBCT with same‐sex couples. © 2005 Wiley Periodicals, Inc. J Clin Psychol/In Session 61: 1429–1438, 2005.