bluuebunny/crossref_metadata_2025_split huggingface dataset:
Scaling of ventral hippocampal activity during anxiety
Authors: Cerquetella Carlo , Gontier Camille , Forro Thomas , Pfister Jean-Pascal , Ciocchi Stéphane 
Published: January 2025

The hippocampus supports a multiplicity of functions, with the dorsal region contributing to spatial representations and memory, and the ventral hippocampus (vH) being primarily involved in emotional processing. While spatial encoding has been extensively investigated, how the vH activity is tuned to emotional states, e.g. to different anxiety levels, is not well understood. We developed an adjustable linear track maze (aLTM) for male mice with which we could induce a scaling of behavioral anxiety levels within the same spatial environment. Using in vivo single-unit recordings, optogenetic manipulations and population-level analysis, we examined the changes and causal effects of vH activity at different anxiety levels. We found that anxiogenic experiences activated the vH and that this activity scaled with increasing anxiety levels. We identified two processes that contributed to this scaling of anxiety-related activity: increased tuning and successive remapping of neurons to the anxiogenic compartment. Moreover, optogenetic inhibition of the vH reduced anxiety across different levels, while anxiety-related activity scaling could be decoded using a linear classifier. Collectively, our findings position the vH as a critical limbic region that functions as an ‘anxiometer’ by scaling its activity based on perceived anxiety levels. Our discoveries go beyond the traditional theory of cognitive maps in the hippocampus underlying spatial navigation and memory, by identifying hippocampal mechanisms selectively regulating anxiety.Significant statementThis study reveals how the ventral hippocampus (vH) functions as an "anxiometer", tuning its activity to different anxiety levels. Using an adjustable linear track maze (aLTM) for mice, we demonstrated that vH activity scales with increased anxiety. By recording single-neuron activity and performing optogenetic manipulation of vH during the aLTM task, we identified key neuronal mechanisms for neuronal scaling during anxiety. Additionally, a linear classifier was used to highlight anxiety-related activity scaling. Our findings advance the understanding of hippocampal function beyond spatial navigation and memory, offering new insights into how the brain regulates anxiety at the neuronal level.
A very low carbohydrate diet improved metabolic profile in congenital generalized lipodystrophy type 4
Authors: Chakraborty Sayantan , Roy Subhankar , Das Debaditya , Chatterjee Sayantani , Sahana Pranab Kumar , Mukhopadhyay Satinath 
Published: January 2025

Summary
A 17-year-old girl presented with recurrent attacks of acute pancreatitis, associated with severe hyperglycemia and hypertriglyceridemia, despite being on intensive insulin therapy for the last 10 years. She had severe acanthosis nigricans, generalized loss of subcutaneous fat and prominent veins over extremities. The serum levels of glucose and triglyceride did not reduce significantly, even with maximally tolerated doses of metformin (2 g), pioglitazone (45 mg) and fenofibrate (160 mg), not uncommonly seen in poor rural families in West Bengal, India. A detailed dietary recall revealed a very high carbohydrate intake (70% of total calorie) with very low protein and fat intake. A switch to a very low carbohydrate (30% of total calorie) diet led to a remarkable improvement in glucose and lipid profiles (the daily insulin requirement came down by 50% and triglyceride level came down to 600 mg/dL from 950 mg/dL). A whole-exome sequencing study confirmed congenital generalized lipodystrophy type 4. A carbohydrate restriction strategy may improve difficult-to-control glycometabolic profile in lipodystrophic subjects on high-carbohydrate diet.

Learning points

Lipodystrophy should be suspected in patient presenting with hyperglycemia, hypertriglyceridemia and low BMI.

A very low carbohydrate diet (30% of total daily calorie intake) may significantly improve glucose and lipid profiles in patients with lipoatrophic diabetes.

Blood glucose may be the most important initial step to control hypertriglyceridemia and risk of pancreatitis in this group of patients.
ИЗМЕНЧИВОСТЬ НЕКОТОРЫХ СЧЕТНЫХ ПРИЗНАКОВ И ПОЛИМОРФИЗМ ФРАГМЕНТА МИТОХОНДРИАЛЬНОЙ ДНК, ВКЛЮЧАЮЩЕГО ГЕН ND1, СИГОВ ГРУППЫ COREGONUS LAVARETUS SENSU LATO ИЗ ВОДОЕМОВ СЕВЕРА ЕВРОПЫ
Authors: СЕНДЕК Д.С. , БОЧКАРЕВ Н.А. , ЗУЙКОВА Е.И. , НОВОСЕЛОВ А.П. , ТИТОВ С.Ф. , АЛЕКСЕЕВ М.Ю. , БОЗНАК Э.И. , ИЛЬМАСТ Н.В. 
Published: January 2025

Филогеографический и морфологический анализы сигов Coregonus lavaretus Европы, уровень полиморфизма гена nd1 мтДНК свидетельствуют об относительно древнем происхождении некоторых популяций, населяющих водоемы западнее Ютландии. Высказывается предположение, что часть популяций в Европе представляют собой остатки первичной волны расселения основателей из Центральной Сибири (бассейн р. Лены). В более поздние волны миграций сигов из Сибири, синхронизированные по времени с событиями повторяющихся нижнечетвертичных оледенений, к западу от Урала расселялись они из нижнего течения крупных водотоков Западной Сибири (реки Обь, Енисей), которые эволюционировали относительно независимо от сигов из Центральной Сибири. В результате повторяющихся событий расселений из разобщенных приледниковых рефугиумов с востока и запада на географическом пространстве Восточной Европы от Балтийского моря до р. Печоры гаплотипы сигов оказались сильно перемешаны. Помимо естественно-исторических причин на картину распределения генетической изменчивости в природных популяциях сигов Восточной Европы в последние десятилетия оказали влияние рыбоводные мероприятия по акклиматизации и/или искусственному поддержанию отдельных популяций.
Phylogeographic and morphological analyzes of the whitefish Coregonus lavaretus of Europe, the level of polymorphism of the mtDNA nd1 gene indicate a relatively ancient origin of the populations inhabiting water bodies west of Jutland. It is suggested that these populations in Europe represent remnants of the primary wave of settlement by founders from Central Siberia (Lena River basin). In later waves of whitefish migrations from Siberia, synchronized in time with the events of repeated Lower Quaternary glaciations, whitefish settled west of the Urals from the lower reaches of large watercourses of Western Siberia (Ob River, Yenisei River), which evolved relatively independently of whitefish from Central Siberia. As a result of repeated events of settlement from disconnected periglacial refugia from the east and west, in the geographical space of Eastern Europe from the Baltic Sea to the Pechora River, whitefish haplotypes were greatly mixed. In addition to natural-historical reasons, the distribution of genetic variability in natural whitefish populations in Eastern Europe in recent decades has been influenced by fish hatchery activities for acclimatization and/or artificial maintenance of populations/species.
ПРИСТРІЙ ДЛЯ АВТОМАТИЗОВАНОГО КОНТРОЛЮ МІРИ КИСЛОТНОСТІ ВОДИ У СИСТЕМІ ОХОЛОДЖЕННЯ
Authors: Удолатій В. Б. 
Published: January 2025

Анотація. Стійкість енергетичного встаткування до агресивного впливу охолоджуючих речовин, в основному, забезпечується шляхом добору й використання корозійно-стійких матеріалів. В існуючих реаліях підвищення корозійної стійкості енергетичного встаткування можливо лише за умови правильної організаціїї процесу охолодження на підґрунті достовірного вимірювання достатньої та необхідної кількості величин якості додаткової й циркуляційної води. Тобто параметрів, які характеризують процеси відкладань на теплопередаючих поверхнях і корозії. Обґрунтовано вдосконалення схемотехнічного рішення датчику визначення міри кислотності охолоджувальної води. Науково-технічне завдання, яке створено запитом практики, вирішується тим, що пропонований волоконно-оптичний рН-метр, що складається з основи, віддзеркалюючого шару, основного світловоду, коаксіального світловоду з літієвого скла, первинного та вторинного розгалужувачів, електрооптичних фільтрів, джерело та фотоприймача випромінювання. Основна відмінність від найближчого аналога полягає у застосуванні основного світловоду револьверного типу.Застосування револьверного світловода у сполученні з оболонкою з літієвого скла дасть змогу у рН-метрі пропонованої конструкції досягти більшої величини чутливості, компенсацію впливу дестабілізуючих факторів за рахунок використання ідентичних матеріалів та збільшення діапазону вимірів величини кислотності середовища. Впровадження до складу суднових інформаційно-вимірювальних систем запропонованого рН-метра дозволить адекватно й вірогідно оцінювати кількісні параметри охолодної води та створювати умови для їх раціонального технічного використання і діагностування об'єктів суднової енергетичної установки.
Isolated and Cumulative Water Quality Effects of two Small Hydropower Plants of a Pantanal Tributary
Authors: Oliveira Valdeci Antônio de , Silva Geovanna Mikaelle Santos , Oliveira Simoni Maria Loverde , Cruz Ibraim Fantin 
Published: January 2025

The construction of small hydropower plants (SHP) can cause several changes in river ecosystems, especially when designed in cascade. Thus, this study aimed to quantify the effects of two SHP operating in cascade and evaluate the individual and cumulative water quality effects on the Ponte de Pedra Stream. The study was developed at the SHP José Gelázio da Rocha and Rondonópolis, both located in Rondonópolis county, state of Mato Grosso, about 15 water quality parameters from the environmental monitoring of the power plants, collected every six months between 2006 to 2013. To evaluate water quality effect, we used the paired Wilcoxon test, and the percentage of change in relation to the natural point, upstream of the hydroelectric plants. The Wilcoxon test showed that downstream of the José Gelázio PCH there was a significant change in all five parameters, causing a 3% increase in temperature, and a 28% reduction in color, 22% in dissolved solids, 20% in total solids and 12% in suspended solids. Downstream of the Rondonópolis PCH there was a significant change in only two parameters, , reducing the temperature by 3% and increasing pH by 1.5%. Regarding the cumulative effects, the reservoirs significantly changed two parameters, causing an 18% increase in total phosphorus and a 48% reduction in total solids. These effects are associated with increased exposure of water to solar radiation and the particle retention process, due to increased hydraulic retention time in the reservoirs. The cumulative effects of the cascade system were 15% greater than the sum of the individual effects, indicating that projects in cascade tend to potentiate the isolated effects.
Enhanced flood prediction using LSTM and climate parameters: multi-station analysis of snowmelt-induced flooding in the Red River of the North
Authors: Atashi Vida , Gorji Hamed Taheri 
Published: January 2025

ABSTRACT
Flooding in cold regions, particularly driven by snowmelt and climate variability, presents complex challenges for accurate prediction and effective risk management. The current study aims to bridge these gaps by integrating all three components – cold region river systems, long short-term memory (LSTM) modeling, and a broader set of climate variables. Specifically, we incorporate additional climate parameters, including air temperature, humidity, solar radiation, and wind speed, into the LSTM model. Using 12 years of hourly water level data (2007–2019) from three USGS stations along the Red River – Pembina, Drayton, and Grand Forks – the model predicts water levels at lead times of 6, 12 h, 1 day, 3 days, and 1 week. The incorporation of climate variables significantly improved short-term prediction accuracy, achieving R2 values of 0.999 for 6-h forecasts across all stations, demonstrating the potential for real-time flood warning systems. For 1-week predictions, R2 values were 0.778 for Grand Forks, 0.816 for Drayton, and 0.864 for Pembina, reflecting a decrease in accuracy with longer prediction horizons. These findings highlight the effectiveness of LSTM models for short-term flood forecasting in snowmelt-prone regions and underscore the need for further refinement to address long-term hydrological forecasting challenges, particularly under variable climatic conditions.
How can we adapt together? Assessing how legal frameworks address collaboration between the urban water sector and spatial planning
Authors: Gomes Costa Tavares Vinagre Vítor Hugo , Fidélis Teresa , Luís Ana 
Published: January 2025

ABSTRACT

Climate change presents novel challenges for water management, both in the context of water excess and scarcity, and it is expected to afflict the world in the coming years. The necessity of strong collaboration between urban water management and spatial planning to facilitate adaptation to climate change has been underlined in the literature. Considering the potential of the legislative context to foster this collaboration, this article examines how the objectives and measures for collaboration are foreseen in a set of legal documents. The article focuses on the Portuguese legal context. As a southern European country, Portugal is situated in one region most susceptible to climate change impacts, including water scarcity and flooding. A systematic document analysis was conducted to examine how collaboration is formally foreseen in a set of legislation, plans, programs, and water management-related contracts. The findings reveal that although plans and programs include recommendations for collaboration, this inclusion is much poorer in regulations where the establishment of the necessary steps remains weak. Contractual arrangements between water sector grantors and concessionaires have shown to be even poorer at fostering such collaboration. Further studies applied to other countries could shed light on this challenge.
Unveiling the impact of the COVID-19 pandemic on water quality: a case study on Ain-Silan and Ain-Karma sources
Authors: Mizane Nour El Houda , Houha Belgacem , Khelifi Amira , Bettache Nabila , Ahmed Salman 
Published: January 2025

ABSTRACT

The water quality may change over time due to a variety of physical, chemical, and biological conditions. The objectives of this study were to use statistical methods to compare the composition of cations and anions in water before and after the COVID-19 pandemic. The statistical method (ordinary least square regression) employed to assess the relationships between water quality parameters involved calculating the coefficient of determination (R2). Two key sampling sites, Ain-Karma (urban, Khenchela city) and Ain-Silan (rural), had frequent sample collection over seven years (2015–2022). Parameters analyzed include electrical conductivity (EC), pH, sodium (Na), magnesium (Mg), calcium (Ca), ammonium (NH4), nitrate (NO3), chloride (Cl), sulfate (SO4), and nitrite (NO2). At Ain-Silan, the regression models show R² values of 0.8708 for Mg, 0.850 for SO4, and 0.7495 for NO3, highlighting their significant changes over time and importance as water quality predictors. At Ain-Karma, NO2, NH4, and Mg exhibit high R2 values of 0.8418, 0.7947, and 0.8347, respectively, underscoring their critical roles in water quality prediction. These strong correlations suggest that fluctuations in these parameters significantly influence water quality, reflecting both anthropogenic and natural processes.
Designing the First Pregnancy Guaranteed Income Program in the United States: Qualitative Needs Assessment and Human-Centered Design to Develop the Abundant Birth Project
Authors: Karasek Deborah , Williams Jazzmin C , Taylor Michaela A , De La Cruz Monica M , Arteaga Stephanie , Bell Sabra , Castillo Esperanza , Chand Maile A , Coats Anjeanette , Hubbard Erin M , Love-Goodlett Latriece , Powell Breezy , Spellen Solaire , Malawa Zea , Gomez Anu Manchikanti 
Published: January 2025

Background
Racial inequities in pregnancy outcomes persist despite investments in clinical, educational, and behavioral interventions, indicating that a new approach is needed to address the root causes of health disparities. Guaranteed income during pregnancy has the potential to narrow racial health inequities for birthing people and infants by alleviating financial stress.

Objective
We describe community-driven formative research to design the first pregnancy-guaranteed income program in the United States—the Abundant Birth Project (ABP). Informed by birth equity and social determinants of health perspectives, ABP targets upstream structural factors to improve racial disparities in maternal and infant health.

Methods
The research team included community researchers, community members with lived experience as Black or Pacific Islander pregnant, and parenting people in the San Francisco Bay Area. The team conducted needs assessment interviews and facilitated focus groups with participants using human-centered design methods. Needs assessment participants later served as co-designers of the ABP program and research, sharing their experiences with financial hardships and government benefits programs and providing recommendations on key program elements, including fund disbursement, eligibility, and amount.

Results
Housing affordability and the high cost of living in San Francisco emerged as significant sources of stress in pregnancy. Participants reported prohibitively low income eligibility thresholds and burdensome enrollment processes as challenges or barriers to existing social services. These insights guided the design of prototypes of ABP’s program components, which were used in a design sprint to determine the final components. Based on this design process, the ABP program offered US $1000/month for 12 months to pregnant Black and Pacific Islander people, selected through a lottery called an abundance drawing.

Conclusions
The formative design process maximized community input and shared decision-making to co-design a guaranteed income program for Black and Pacific Islander women and people. Our upstream approach and community research model can inform the development of public health and social service programs.
Enteral nutrition strategies in high-risk newborns
Authors: Cinková Nikola , Šrojtová Petra , Letenayová Ivana , Doboš Dušan , Brucknerová Jana , Mičevová Jana , Dolníková Dana , Brucknerová Ingrid 
Published: January 2025

Abstract
Necrotizing enterocolitis (NEC) is one of the most devastating intestinal disorders in neonates, yet the pathophysiology remains incompletely understood. Prematurity, bacterial dysmicrobia, intestinal ischemia and enteral nutrition are considered to be the fundamental risk factors for the development of necrotizing enterocolitis. Various feeding practices are being studied with the aim to find the best approach to protect infants from the necrotizing enterocolitis. In the group of high-risk neonates, the common practice of delayed introduction of enteral feeding has long been considered as a good rationale. However, in recent years, the importance of enteral nutrition has been extensively studied and it is suggested that minimal enteral feeding may play a beneficial role in the prevention of the disease. Studies proved that the absence of enteral nutrition is associated with intestinal mucosal atrophy, diminished intestinal growth, delayed maturation of intestinal enzymes and increased permeability and bacterial translocation. Minimal enteral feeding can on the other hand stimulate the development of the immature gastrointestinal tract and reduce systemic inflammatory responses by promoting proliferation of gut microbial diversity.
Citation Concept Analysis (CCA) of concepts introduced by Pierre Bourdieu: Measuring their impact across fields and periods
Authors: Bornmann Lutz , Crothers Charles , Haunschild Robin 
Published: January 2025

ABSTRACT

Purpose
Citations can be used in evaluative bibliometrics to measure the impact of papers. However, citation analysis can be extended by a multi-dimensional perspective on citation impact which is intended to receive more specific information about the kind of received impact.

Design/methodology/approach
Bornmann, Wray, and Haunschild (2019) introduced citation concept analysis (CCA) for capturing the importance and usefulness certain concepts have in subsequent research. The method is based on the analysis of citances – the contexts of citations in citing papers. This study applies the method by investigating the impact of various concepts introduced in the oeuvre of the world-leading French sociologist Pierre Bourdieu.

Findings
We found that the most cited concepts are ‘social capital’ (with about 34% of the citances in the citing papers), ‘cultural capital’, and ‘habitus’ (both with about 24%). On the other hand, the concepts ‘doxa’ and ‘reflexivity’ score only about 1% each.

Research limitations
The formulation of search terms for identifying the concepts in the data and the citation context coverage are the most important limitations of the study.

Practical implications
The results of this explorative study reflect the historical development of Bourdieu’s thought and its interface with different fields of study.

Originality/value
The study demonstrates the high explanatory power of the CCA method.
Optimisation and Synthesis of Single Blade Vibration Motion in Airflow
Authors: Beresnevics V. , Viba J. , Irbe M. , Cerpinska M. , Vutukuru S.K. 
Published: January 2025

Abstract
The study focuses on wind flow energy harvesting technology utilising the vibration method. The one-degree-of-freedom mathematical model comprises a flat plate connected to a foundation via an elastic element, subjected to airflow induced by the wind. Energy accumulation occurs within a generator. The braking force exerted by the generator can assume a constant, linear, or non-linear relationship with plate velocity. Oscillation motion is induced by altering the plate area within each oscillation cycle, with maximum area exposure to the windward motion and minimum during leeward movement. Control switches, functioning as level functions, facilitate motion synthesis and simulation by simplifying the description of plate area and generator switching control in the phase plane. Additionally, a control switching delay is introduced for plate area variation, described in terms of velocity and coordinate levels. The paper presents computer simulation results in the form of phase diagrams and time responses, followed by an analysis of generated power and energy extraction efficiency.
Mould Resistance of Paper Plaster Made from Cellulose-Containing Waste
Authors: Raamets J. , Nutt N. , Rudisaar R. , Nei L. , Olle M. 
Published: January 2025

Abstract
The objective of this study was to determine mould resistance of the plaster made from waste paper. To study the plaster quality, two laboratory tests were conducted. First, mould resistance of a dry plaster was studied, and second, mould resistance of a wet plaster was tested. Since wet plaster mix must be used for plastering, the resulting surfaces are extremely wet. The plaster placed on the wall would dry for at least two weeks under favourable conditions (sufficient ventilation and temperature). During this period, there is a great risk that the plaster might become mouldy. Another risk of becoming mouldy occurs when an already plastered wall receives moisture (e.g., water damage). The experiments carried out under laboratory conditions showed that in an environment with high relative humidity the plaster did not become mouldy.