bluuebunny/crossref_metadata_2025_split huggingface dataset:
F04Prognostic value of Dopplerometry during antirecurrent hormonal therapy in patients with hyperplastic process of the endometrium
Authors: Fedorova E. V. , Lipman A. D. , Khokhlova I. D. , Pobedinski N. M. 
Published: March 2003

BackgroundThe purpose of study was to find out changes of Doppler parameters in all uterine arteries during antirecurrent hormonal courses and to define their role in prediction of outcomes.Method53 patients receiving hormonal therapy (Norcolut, Provera, Danazol) after D & C were undergone 6 months monitoring by transvaginal ultrasound with Color Flow Mapping and Doppler assessment of the main uterine, arcuate, radial and basal arteries. The mean values of resistance indices (RI) were calculated after retrospective division into groups with effective (n = 41) and effectless (n = 12) treatment. Investigated RI data were used for statistical creation of prognostic upper and lower cut‐off levels (for P < 0.05).ResultsThe resistance indices were:

Healthy
Effective  treatment
Effectless  treatment
Cut‐off intervals  for P < 0.05

Uterine arteries
0.88
0.86
0.83
0.83–0.87

Arcuate arteries
0.78
0.74
0.72
0.65–0.80

Radial arteries
0.71
0.73*
0.65*
0.60–0.75

Basal arteries
0.57
0.62
0.57
0.48–0.68

– p < 0.10

ConclusionFor predicting effectiveness of hormonal treatment after two months from its beginning Doppler measurements should be carried out in Radial Arteries and RI must exceed 0.75.
Multiple pregnancy F41Early versus late multifetal pregnancy reduction, comparison of pregnancy outcome
Authors: Jaffa A. J. , Hat‐Toov J. , Fait G. , Wolman I. , Gull I. , Achiron R. , Lipitz S. 
Published: March 2003

BackgroundTo evaluate the pregnancy outcome of selective second‐trimester multifetal pregnancy reduction (MFPR) compared to late first‐trimester and early first‐trimester MFPR in triplets and quadruplets.MethodThe study groups comprised of 46, 47, and 48 patients who underwent MFPR at mean gestational of 11.2 (group A), 13.6 (group B), and 18.5 (group C) weeks, respectively. Patients of groups B and C underwent ultrasonographic fetal malformation screening. Some patients of group C had amniocentesis for chromosomal evaluation.ResultsNo statistically significant difference was found between Group A, B, C regarding Pregnancy loss (4%, 4.3%, 2.5%, respectively), mean gestational age at delivery (35.8, 35.7, 35.8, respectively), and mean birth weight (2190, 2140, 2190, respectively). In group C fetal structural anomalies and chromosomal abnormalities were found in 4.2%, and 4.2% of pregnancies, respectively.ConclusionPregnancy outcome was similar after MFPR at different stages of pregnancy. Selective second‐trimester MFPR is associated with favorable perinatal outcome and may facilitate detection of structural and chromosomal anomalies before the procedure and selective reduction of the affected fetus.
F43Feto‐placental Doppler measurements pre and post laser coagulation in severe twin–twin transfusion syndrome
Authors: Carreras E. , Deprest J. , Van Schoubroeck D. , Roma L. , Van Assche A. , Cabero L. , Gratacos E. 
Published: March 2003

ObjectiveThe aim of the study was to know what fetal hemodynamic response to therapeutical fetoscopic laser was, specially in the donor.Material and methodsPatients with severe TTS undergoing laser coagulation of placental anastomoses (n = 25) were included. Doppler measurements (Accuson Aspen) were performed in the Umbilical artery, Middle cerebral artery, ductus venosus and Umbilical vein of both fetuses preoperatively and on days 1, 3 and 5 postlaser.ResultsVenous pulsatility indices tend to decrease in the recipient while they increase in the donor. Increased PI and/or appearance of pulsations in the UV was observed in 75% of donors, which was accompanied but one or more signs of hydrops in 20% of cases. These did not constitute signs of poor prognosis.ConclusionsWe hypothesize that venous return in the donor fetus increases after laser coagulation, which could explain a transient overload phase, which in any case does not imply a poorer prognosis.
F44Serial amniocentesis in twin Transfusion syndrome
Authors: Szaflik K. , Borowski D. , Wilczyñski J. , Wyrwas D. , Kunert A. , Hincz P. , Ciesielski A. 
Published: March 2003

BackgroundThe aim of our study was to estimate the efficiacy of serial amniocentesis in cases of acute polyhydramnion in TTS.MethodThe study group consisted of 13 pairs of twins with sonographically confirmed hydramnios. After the examination patients were prepared for amnioreduction. During the procedure the excess of amniotic fluid was removed through the punction needle.ResultsThe mean gestational age was 24.3 ± 2.9 weeks in the range 22–29 weeks. In 6 cases polyhydramnion/oligohydramnion was found. The therapy of TTS was based mainly on serial amniocentesis.The mean gestational age during delivery was 27.6 ± 3 weeks. The mean interval between the diagnosis and delivery was 3.3 weeks. In all cases the deliveries were preterm. The mean donor weight was 730 ± 290 g and the mean recipient weight was 1145 ± 435 g. The difference between the recipients and donors was approximately 37%. In 7 cases we observed an intrauterine demise of one fetus. The 5th min Apgar score was 1 pt (median). When the analysis was performed after exclusion of stillborns, the median Apgar score for donors and recipients was 4 and 2 pt, respectively.ConclusionSerial amniocentesis are effective in significant prolongation of gestation (the mean interval between diagnosis and delivery 24 days). The improvement of perinatal outcomes in twin gestations complicated by TTS can be achieved by the combination of serial amniocentesis and the laser ablation.
Second and third trimester Doppler F46Fetal cerebral and adrenal blood velocimetry in predicting hypoxia of the fetus
Authors: Breborowicz G. H. , Dubiel M. , Marsal K. , Gudmundsson S. 
Published: March 2003

BackgroundAnimal studies have shown that hypoxic fetuses redistribute their blood flow, giving preferential supply to the brain, heart and adrenal glands. The aim of this study was to evaluate blood velocity waveforms in the fetal middle adrenal artery and cerebral arteries in relation to the outcome of high‐risk pregnancy.MethodsMiddle adrenal artery and anterior, middle and posterior cerebral arteries were recorded in 102 pregnancies complicated by pregnancy induced hypertension between 27 and 41 weeks of gestation. Signs of the fetal ‘adrenal‐sparing’ were considered present when pulsatility index (PI) was below the 95% confidence interval. Signs of fetal brain‐sparing were considered present when the cerebral arterial PI were < mean −2 SD of the normals and cerebroplacental PI ratio < 1.08. The blood velocimetry results were related to perinatal outcome.ResultsAdrenal velocimetry was strongly associated with aDVerse perinatal outcome, being significant for all studied parameters. All perinatal mortality showed signs of adrenal sparing. Adrenal sparing, but not brain sparing, was correlated with fetal acidosis. Combining adrenal velocimetry with brain velocimetry shown worser predictive results than adrenal velocimetry itself.ConclusionFetal adrenal sparing is more predictive of perinatal outcome in high‐risk pregnancies and might be maintained longer than the brain‐sparing sign.
F05Is TV‐USG detection of myometrial invasion of endometrial cancer predictible?
Authors: Tekin B. , Özalp S. , Hassa H. , Şener T. , Yalçin Ö. T. , Etiz E. 
Published: March 2003

BackgroundThe aim of the study is to determine effectiveness of transvaginal ultrasound (TV‐USG) examination in predicting myometrial invasion of the endometrial cancer.MethodSome patients of endometrial cancer, were examined under TV‐USG examination. All TV‐USG procedures were done by the same person and by the same ultrasound equipment between 1.9.1998 and 31.12.1999. After then, patients were operated, and pathological examination of the specimens were done as routine procedure.ResultsTwenty‐six cases who were in this research, were in stage 1 except 4 who were in stage 4. Histopathologic type of 22 cases was endometrioid cell cancer and grade‐1 in 58.3% cases. Ultrasound examination revealed 76.9% similarity with pathological results. Positive predictivity was 94.4% and the negative predictivity was 37.5%.ConclusionTV‐USG diagnosis of endometrial invasion of cancer, may be a useful technique in predetermining the way of treatment while the depth of invasion is an important key as well as histopathology and grade of the tumor.
F60Umbilical vein blood flow in growth restricted fetuses
Authors: Rigano S. , Ferrazzi E. , Bozzo  , Giovannini N. , Bellotti M. , Galan H. , Battaglia F.C. 
Published: March 2003

ObjectiveThe present study was designed to determine whether specific umbilical blood flow is reduced in IUGR fetuses.SubjectsThirty‐seven IUGR fetuses of different clinical severity were examined by Doppler ultrasound within four hours of the last nonstress test prior to delivery.MethodAbsolute and weight specific umbilical vein (UV) flow were calculated from measurements of UV diameter and UV mean velocity. UV diameter, velocity and UV flow were calculated also per unit head (HC) or abdominal circumference (AC) and correlated with gestational age.ResultsUV flow per kilogram was significantly lower in the more severe IUGR fetuses (abnormal umbilical arterial p.i.) than in normal comparable fetuses (P < 0.001). UV flow per unit head circumference was significantly lower in the three groups (P < 0.001) than in the control population. The UV diameter/HC was normal whereas UV velocity/HC was significantly lower in IUGR fetuses than in comparable controls.ConclusionsThe present study clearly establishes that umbilical venous blood flow is reduced in IUGR fetuses on a weight specific basis. The sonographic growth parameter which best distinguishes umbilical flow differences of IUGR fetuses from normal fetuses is the head circumference.
F63Ultrasound guided fetal cystoscopic therapy for posterior urethral valves (PUV)
Authors: Welsh A. W. , Agarwal S. , Fisk N. M. 
Published: March 2003

BackgroundThe commonest cause of obstructive uropathy in males is PUV, with well‐recognised ultrasonographic features and a mortality of up to 95% if associated with oligohydramnios. Palliative treatment (vesicoamniotic shunting) has increased survival, but with a high complication rate and significant incidence of long‐term renal impairment. We evaluated the diagnostic and therapeutic role of thin gauge embryofetoscopy in suspected PUV.MethodA joint fetal medicine and paediatric urological team performed the procedures under local anaesthetic. Nine fetuses were assessed, mean gestation 22 weeks (7 subsequently confirmed PUV, 1 unconfirmed, 1 suspected urethral atresia). After confirmation of urinary electrolyte normality, a 1.3‐mm semirigid fetoscope (Karl Storz Ltd) was inserted under ultrasound guidance into the dilated fetal bladder. Fetoscopic features were documented and an attempt made to enter the dilated upper posterior urethra. Two therapeutic procedures were assessed: valvular flushing under pressure and guidewire passage.ResultsThe hypertrophied bladder neck was seen in 7 cases, the posterior urethra entered in 4 and the obstruction visualised in 2. Five therapeutic procedures were attempted (2 flushing, 3 guidewire). One case flushed therapeutically was confirmed after delivery to have a patent urethra.ConclusionsSome cases of PUV may be treated in utero. Further studies are indicated to explore fetoscopy as a therapeutic tool.AcknowledgementsAlec Welsh is supported by a Research Training Fellowship from RCOG/WellBeing.
F713D CDS of fibroid pre‐ and post‐embolization
Authors: Fleischer A.C. ,   E. Donnelly, Campbell M. , Mazer M. , Lipsitz N. 
Published: March 2003

ObjectiveEvaluate and quantitate changes in fibroid vascularity and volume preand postembolization with 3D Color Doppler sonography (CDS).MethodQuantitative 3D CDS was performed immediately prior to, 1 day, 3 months, and 6 months postembolization in 20 patients.ResultsAll patients had symptomatic relief. Changes in vascularity were greatest 1 day postembolization whereas the most significant changes in volume occurred on the 3 month follow‐up scan.ConclusionQuantitative 3D CDS provides accurate information regarding fibroid vascularity and volume postembolization. This data may be helpful in monitoring response to treatment as well as detection of complications.
F73New modes of capture by freehand three‐dimensional ultrasound in the prenatal diagnosis of fetal anomalies
Authors: Guerra F. , Gutiérrez R. , Herrera L. , Anwandter C. , Caro J. , Aguilar R. , Isla A. 
Published: March 2003

BackgroundThe aim of this study was to see the contribution of three different modes of capture of data by the freehand three‐dimensional ultrasound (3D US) in the prenatal diagnosis of fetal anomalies.MethodWe studied a total of 34 pregnant women. In all of them a fetal anomaly was previously assessed by 2D US. Planar US probes and a 3D software (3D‐ViewTM) were used on a digital Gaia 8800 scanner. Three modes of data capture were employed: volume capture (to capture a volume), static capture (to capture motion; a combination of B‐mode and M‐mode), and free style capture (to capture a big region of interest; ROI), then the most suitable screen presentation was used according to the mode of capture.ResultsWe found a total of 41 anomalies on 34 fetuses which are: Heart (17), abdomen (8), central nervous system (6) and miscellaneous (10). We were able to see all anomalies previously detected by 2D US. By using volume capture and rendering image we were able to detect also anomalies of fingers and face, no previously detected by 2D. However volume capture was the most difficult mode to perform. Static capture was the most suitable to study fetal heart malformations (as A‐V canal) and arrhythmias. Free style capture give us a B‐mode digital video of the ROI (hydrocephalus, spina bifida, gastroschisis, omphalocele, adominal cysts, kidney malformations). Good pictures by using the last two modes of capture were easy to obtain. We also benefit of all the advantages of using digital technology, like to have the information as a virtual patient.ConclusionThe appropriate use of different modes of capture of data by free hand 3D US in combination with 2D US gives a new perspective of using this new technology in the diagnosis of fetal anomalies.
F09Detection of pelvic recurrent disease with transvaginal color‐Doppler analysis in women treated for gynecologic malignancy
Authors: Testa A. C. , Ciampelli M. , Mastromarino C. , Lopez R. , Mancuso S. , Scambia G. 
Published: March 2003

BackgroundTo evaluate Color Doppler characteristics of small tumor recurrences detected within the pelvis in follow‐up patients treated for gynecologic malignancy.MethodOut of 310 patients monitored for gynecologic malignancy, a selected group of 14 patients, with small size pelvic masses located in the central region of the pelvis detected by transvaginal ultrasound, underwent a color Doppler evaluation.A subjective assessment of the vascularization (vascular score), the lowest Resistance Index (RI), the highest Peak Velocity (PV) and the highest Time Averaged Maximum Velocity (TAMXV) of the vessels detected within the lesion were considered for the analysis.ResultsColor score of tumor recurrences (No 7) was significantly higher in comparison to benign lesions (No 7) (2.6 ± 0.5 vs. 2 ± 0, P < 0.05). The malignant lesions showed significantly higher mean values of PV and TAMXV when compared to benign ones (17.9 ± 4.3 cm/s vs. 7.5 ± 3 cm/sec, P < 0.0001; 9.7 ± 2.2 cm/s vs. 3.5 ± 3 cm/s, P < 0.01).ConclusionsColor Doppler analysis added to transvaginal ultrasonography seems to be an helpful tool in the evaluation pelvis at an early stage of recurring tumor in the pelvis.
F100Dopplerometry at the prenatal diagnosis of congenital defects
Authors: Santavy J. , Lubusky M. , Polak P. , Hyjanek J. 
Published: March 2003

BackgroundPulse and colour Dopplerometry is going to be more and more routine investigation in the frame of specialised prenatal investigation. Despite the huge number of the works in this field in the past years we have found only very limited information about utilisation of these both methods at the cases of congenital defects found in utero, especially in the first trimester of pregnancy.MethodDuring the past two years we have investigated both by pulse and colour Doppler mostly cord vessels, art. cerebri media, art. renalis and truncus arteriosus. By the colour Doppler we evaluated heart, moving of the chest and we assessed placental blood circulation in lacunas.ResultsOur collection consists from 28 pregnant women, where we have found congenital defects. There were chromosomal aberrations, morphological defects, serious intrauterine hypoplasias and Rh incompatibility there. Evaluation was not possible by the absolute values and so we divided the curves into four groups: higher, normal and lower levels, and zero flow. The results are not specific for individual defects, as we expected, but it is an option to utilise them at a suspicion for abnormal intrauterine findings.ConclusionDopplerometry at the congenital defects has its limited value but it is helpful at the complex evaluation of the foetus health condition.
Does texture analysis improve breast ultrasound precision?
Authors: Bader W. , Böhmer S. , Van Leeuwen P. , Hackmann J. , Westhof G. , Hatzmann W. 
Published: March 2003

AbstractObjectiveTo evaluate the possibility of distinguishing between benign and malignant breast tumors using a computer‐aided evaluation of echogenicity and echostructure of ultrasound findings at certain focal points.Study designThe ultrasound images from 89 cases of breast tumor were documented under standardized conditions using a linear array machine and 7.5 MHz transducer. In each sonographic image, the maximum area of the ‘region of interest’ of the tumor was marked and then subjected to consecutive statistical analysis and correlation with the histological findings. For evaluation of tumor status eight parameters of first and second order texture statistics (gray level histogram, Fourier analysis, co‐occurrence matrix) were applied.ResultsBenign tumors were clearly distinguished from carcinomas in the evaluation of the co‐occurrence matrix and the Fourier analysis on the basis of Wilcoxon and Student t‐test (P < 0.05) but not in the gray level histogram. Using logistic regression a sensitivity of 73.8% and a specificity of 54.2% were obtained. A statistically significant difference between benign tumors and moderately differentiated together with poorly differentiated carcinomas could be demonstrated.ConclusionThis study concludes that texture analysis appears to distinguish between benign and most malignant tumors. A computer texture analyzing system is able to improve the subjective assessment of ultrasound images of the breast but can not replace it. Where the limits of subjective assessment of a given tumor are reached, computerized texture analysis will provide additional information in the differentiation of benign from malignant findings. Copyright © 2000 International Society of Ultrasound in Obstetrics and Gynecology
Constriction band of the arm following insertion of a pleuro‐amniotic shunt
Authors: Brown R. , Nicolaides K. 
Published: March 2003

AbstractIn a 23‐week fetus with a large left‐sided pleural effusion a double pigtail pleuro‐amniotic shunt was inserted uneventfully. A healthy infant was delivered at 38 weeks' gestation. One end of the shunt was in the thoracic cavity but the other end was found wrapped around the upper arm resulting in a constriction band. There was no impairment of the vascular supply to the limb or in its motor or sensory function and by 6 months of age there was only a faint ring still apparent around the upper arm. Copyright © 2000 International Society of Ultrasound in Obstetrics and Gynecology
Ultrasound markers of fetal chromosomal abnormality: a survey of policies and practices in UK maternity ultrasound departments
Authors: Maclachlan N. , Iskaros J. , Chitty Lyn 
Published: March 2003

AbstractObjectiveTo evaluate the management of pregnancies where the fetus was found to have one or more sonographic markers of possible fetal chromosomal abnormality.DesignProspective anonymous postal survey of UK obstetric ultrasound units.Main outcome measuresThe management of pregnancies where the fetus is found to have a sonographic marker of aneuploidy.PopulationAll 252 maternity ultrasound units in the United Kingdom.MethodsPostal questionnaire to the superintendent sonographer in routine maternal ultrasound departments.ResultsQuestionnaires were returned from 179 maternity units (71%). Of the respondents 94% offered a fetal anomaly scan at 16–20 weeks' gestation and 59% performed a dating scan at 10–14 weeks. Screening for Down syndrome was available in 99% of all maternity units.The recognition of sonographic ‘soft signs’ for possible fetal chromosomal abnormality varied considerably between the units. When sonographers were asked about their unit's policy regarding offering amniocentesis to women with sonographic markers, 8–78% discussed amniocentesis when the marker was isolated and 53–88% when another abnormality was found.Eighty nine percent of units documented the abnormal ultrasound findings in the hospital notes and 88% of the women were informed of the findings regardless of the intention to offer amniocentesis.ConclusionThe practice of routine ultrasound examination is well established in UK, though precise policies vary. The existing wide variations in management policies possibly reflect a lack of data derived from low risk populations. There is a need to collect such data from low risk populations with known screening practices so that national guidelines to standardize practice can be formulated. Copyright © 2000 International Society of Ultrasound in Obstetrics and Gynecology
The influence of maternal exercise on placental blood flow measured by Simultaneous Multigate Spectral Doppler Imaging (SM‐SDI)
Authors: Feiner B. , Weksler R. , Ohel G. , Degani S. 
Published: March 2003

AbstractObjectiveTo evaluate the effect of maternal isometric exercise on the placental blood flow as reflected by the velocimetric indices PI and RI derived from placental arteries.SubjectsThirty‐four healthy women with normal singleton pregnancies between 22 and 35 weeks of gestation.MethodsAll subjects underwent an isometric handgrip exercise test. Maternal blood pressure and heart rate together with placental PI and RI were measured at rest, during the exercise and in the post‐exercise recovery phase. All Doppler measurements were obtained using the Simultaneous Multigate Spectral Doppler Imaging (SM‐SDI) technique, a new ultrasound modality that enables a Doppler study of multiple locations to take place within a very short time.ResultsThere was a significant increase in the mean values of the maternal blood pressure and heart rate during the exercise and a significant decline in the recovery phase. There was no significant change in the mean values of the Doppler indices throughout the examination.ConclusionIsometric handgrip exercise test during pregnancy does not affect the impedance of the placental circulation. Copyright © 2000 International Society of Ultrasound in Obstetrics and Gynecology