bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gone with the stream: Functional connectivity of a cold‐water coral at basin scale
Authors: Matos Fábio L. , Aguzzi Jacopo , Company Joan B. , Cunha Marina R. 
Published: October 2023

AbstractLophelia pertusa reefs are vulnerable deep‐sea ecosystems and their ecological integrity partly depends on the connectivity and availability of suitable habitat. Moreover, connectivity is a guiding principle in marine conservation planning, particularly for spatial prioritization and for the design of networks of marine protected areas. We estimated the functional seascape connectivity of L. pertusa in the Mediterranean Sea and provide a framework for prioritizing habitat areas for the species conservation. These goals were achieved by simulating transport and potential dispersal of virtual larvae using biophysical modeling and assessing habitat availability based on the suitability and spatial arrangement of the seascape and inter‐annual climatological variability. Habitat availability was estimated using a network analysis and accounting for the attributes of habitat areas (i.e., size and quality). The connectivity among Mediterranean ecoregions was weak and an increase in the frequency of climate‐driven events (e.g., dense shelf water cascading) may worsen this scenario. However, the potential exchange of larvae between patches within the same ecoregion was high, favoring populations resilience to local disturbances. The analysis of habitat availability allowed identifying important habitat areas for the connectivity of the L. pertusa including the Gulf of Lion, the Apulian and Sicily Island continental margin. Some of the habitat areas identified as important for the connectivity of the L. pertusa are exposed to intense anthropogenic pressures, that may act synergistically with climate change imposing greater challenges to species conservation. These habitat areas may be prioritized in future management and conservation actions targeting L. pertusa.
The Use of High‐Temperature Semi‐Batch Radical Polymerization to Synthesize Acrylate Based Macromonomers and Structured Copolymers
Authors: Bygott Elizabeth G. , Hutchinson Robin A. 
Published: October 2023

AbstractA high‐temperature starved‐feed semi‐batch operating policy is developed to produce p(acrylates) with high macromonomer content, taking advantage of side reactions inherent to acrylate radical polymerization. This operating strategy results in significantly higher macromonomer content for the polymerization of isobornyl acrylate (iBoA) versus n‐butyl acrylate (BA) under identical operating conditions. This is because steric hindrance favors fragmentation (i.e., terminal double bond (TDB) formation) over addition (i.e., short‐chain or long‐chain branch (LCB) formation), thus increasing the p(iBoA) TDB content and decreasing polymer dispersity. The p(iBoA) macromonomer solution serves as an excellent addition‐fragmentation agent to polymerize a second monomer in a single pot process controlled by sequential feeding, as demonstrates by the production of iBoA‐BA block and comb copolymer structures at different temperatures and macromonomer concentrations. The incorporation of the p(iBoA) macromonomer into a copolymer product is verified by various techniques, including polymer fractionation followed by TDB, composition, and molar mass analyses. Reaction temperature plays a key role in determining whether a blocky versus comb copolymer structure is produced. The ability to synthesize block and comb copolymers by radical polymerization without a mediating agent offers the potential to efficiently produce structured copolymers for industrial applications.
Advancements in Electrospun Nanofibrous Membranes for Improved Waterproofing and Breathability
Authors: Liu Shude , Jun Seong Chan , Zhang Shichao , Wang Fei , Yu Jianyong , Ding Bin 
Published: October 2023

AbstractElectrospun nanofibrous membranes have attracted significant interest due to their captivating waterproof and breathable characteristics, stemming from the presence of interconnected and hydrophobic channels within these enhanced textiles. These distinctive traits bestow upon them substantial potential across various domains, encompassing applications in medical dressings, masks, and protective clothing. However, they also give rise to concerns about their durability, compromised waterproofing performance, limited breathability, insufficient mechanical strength, and high production costs. Furthermore, the manufacturing processes of electrospun waterproof and breathable membranes (WBMs) may carry adverse environmental implications, necessitating improvements in sustainability and ecological compatibility. This study begins with a concise overview of the operational principles and criteria for performance evaluation relevant to electrospun WBMs, providing comprehensive guidelines to drive future research. Following this, the authors delve into a thorough exploration of typical fabrication techniques and the prevailing strategies, exemplified by noteworthy ongoing research initiatives. Last, the existing challenges are outlined to foster the development of WBMs. In addition, future research directions and perspectives are presented to expedite the advancement of WBMs and support their commercial implementation. It is anticipated that this comprehensive review will offer pragmatic recommendations for researchers dedicated to the advancement of WBMs.
Does LinkedIn cause imposter syndrome? An empirical examination of well‐being and consumption‐related effects
Authors: Marder Ben , Javornik Ana , Qi Kang , Oliver Sebastian , Lavertu Laura , Cowan Kirsten 
Published: October 2023

AbstractWe attend to the unexamined intersection between professional social network site (SNS) usage and imposter syndrome. Specifically, we provide the first examination of: do such sites cause imposter thoughts (“others think I am more competent than I think I am”); if so, why and when this happens, and what effect this has on well‐being and consumption‐related results. Supported by objective self‐focused attention theory and two online experiments, we show that professional SNS usage heightens professional self‐focused attention, triggering imposter thoughts. This results in negative emotions and consumption‐related effects. We further examine two boundary conditions, showing that effects are reduced for individuals high in narcissism or work centrality. From these findings, we extend the sociocognitive theorization of the imposter phenomenon by uncovering, first, context‐specific self‐focused attention as the reason “why” people feel imposter‐ish in particular circumstances and second, consumption‐related consequences. We further contribute imposter thoughts as a new alternative explanation for negative emotions experienced whilst using professional SNSs.
Designing the digitalized guest experience: A comprehensive framework and research agenda
Authors: Youssofi Alexandra , Jeannot Florence , Jongmans Eline , Dampérat Maud 
Published: October 2023

AbstractDigital transformation has emerged as a critical necessity for hospitality, a sector that traditionally prioritizes human interaction and personalized experiences. While prior research has explored the impact of digital technologies on the realized guest experience, there is a lack of work that studies their influence on the intended guest experience, as designed by hoteliers. Drawing on existing literature on customer experience management and digitalization in hospitality, this research aims to understand the psychological mechanisms by which digital technologies enhance the intended digitalized guest experience. We conducted two qualitative studies, involving 22 hotel professionals and 18 consumers. By consolidating these different theoretical and practical perspectives, we propose a conceptualization of the intended digitalized guest experience and present an integrative framework that includes the mediating and reciprocal role of consumer‐ and professional‐based psychological mechanisms, along with antecedents, outcomes, and contingency factors. These findings have practical implications for hotel professionals, enabling them to leverage appropriate digital strategies for successful guest experiences. The article concludes with specific recommendations to managers on how to design a unique guest experience. These recommendations include designing a game‐like experience, developing “care” as a new source of digital value creation, and providing training to the staff to enhance their creativity.
HIF‐1α regulates the cell viability in radioiodine‐resistant papillary thyroid carcinoma cells induced by hypoxia through PKM2/NF‐κB signaling pathway
Authors: Wang Dong , Liu Xiaoqian , Li Meijing , Ning Jinyao 
Published: October 2023

AbstractThe curative treatment options for papillary thyroid cancer (PTC) encompass surgical intervention, radioactive iodine administration, and chemotherapy. However, the challenges of radioiodine (RAI) resistance, metastasis, and chemotherapy resistance remain inadequately addressed. The objective of this study was to investigate the protective role of hypoxia‐inducible factor‐1α (HIF‐1α) in 131I‐resistant cells and a xenograft model under hypoxic conditions, as well as to explore potential mechanisms. The effects of HIF‐1α on 131I‐resistant BCPAP and TPC‐1 cells, as well as the xenograft model, were assessed in this study. Cell viability, migration, invasion, and apoptosis rates were measured using Cell Counting Kit‐8, wound‐healing, Transwell, and flow cytometry assays. Additionally, the expressions of Ki67, matrix metalloproteinase‐9 (MMP‐9), and pyruvate kinase M2 (PKM2) were examined using immunofluorescence or immunohistochemistry assays. Sodium iodide symporter and PKM2/NF‐κBp65 relative protein levels were detected by western blot analysis. The findings of our study indicate that siHIF‐1α effectively inhibits cell proliferation, cell migration, and invasion in 131I‐resistant cells under hypoxic conditions. Additionally, the treatment of siHIF‐1α leads to alterations in the relative protein levels of Ki67, MMP‐9, PKM2, and PKM2/NF‐κBp65, both in vivo and in vitro. Notably, the effects of siHIF‐1α are modified when DASA‐58, an activator of PKM2, is administered. These results collectively demonstrate that siHIF‐1α reduces cell viability in PTC cells and rat models, while also mediating the nuclear factor‐κB (NF‐κB)/PKM2 signaling pathway. Our findings provide a new rationale for further academic and clinical research on RAI‐resistant PTC.
Band‐Specific Altered Cortical Connectivity in Early Parkinson's Disease and its Clinical Correlates
Authors: Conti Matteo , Guerra Andrea , Pierantozzi Mariangela , Bovenzi Roberta , D'Onofrio Valentina , Simonetta Clara , Cerroni Rocco , Liguori Claudio , Placidi Fabio , Mercuri Nicola Biagio , Di Giuliano Francesca , Schirinzi Tommaso , Stefani Alessandro 
Published: October 2023

AbstractBackgroundFunctional connectivity (FC) has shown promising results in assessing the pathophysiology and identifying early biomarkers of neurodegenerative disorders, such as Parkinson's disease (PD).ObjectivesIn this study, we aimed to assess possible resting‐state FC abnormalities in early‐stage PD patients using high‐density electroencephalography (EEG) and to detect their clinical relationship with motor and non‐motor PD symptoms.MethodsWe enrolled 26 early‐stage levodopa naïve PD patients and a group of 20 healthy controls (HC). Data were recorded with 64‐channels EEG system and a source‐reconstruction method was used to identify brain‐region activity. FC was calculated using the weighted phase‐lag index in θ, α, and β bands. Additionally, we quantified the unbalancing between β and lower frequencies through a novel index (β‐functional ratio [FR]). Statistical analysis was conducted using a network‐based statistical approach.ResultsPD patients showed hypoconnected networks in θ and α band, involving prefrontal‐limbic‐temporal and frontoparietal areas, respectively, and a hyperconnected network in the β frequency band, involving sensorimotor‐frontal areas. The θ FC network was negatively related to Non‐Motor Symptoms Scale scores and α FC to the Movement Disorder Society‐Sponsored Revision of the Unified Parkinson's Disease Rating Scale part III gait subscore, whereas β FC and β‐FR network were positively linked to the bradykinesia subscore. Changes in θ FC and β‐FR showed substantial reliability and high accuracy, precision, sensitivity, and specificity in discriminating PD and HC.ConclusionsFrequency‐specific FC changes in PD likely reflect the dysfunction of distinct cortical networks, which occur from the early stage of the disease. These abnormalities are involved in the pathophysiology of specific motor and non‐motor PD symptoms, including gait, bradykinesia, mood, and cognition. © 2023 International Parkinson and Movement Disorder Society.
Ultrabroadband (DC–80 GHz) RF MEMS DC/capacitive load shunt switch
Authors: Narang Niharika , Shrivastava Pranav K. , Basu Ananjan , Singh Pushpapraj 
Published: October 2023

AbstractThis study presents the design and fabrication of a novel direct current (DC)/capacitive radio frequency (RF) Micro‐Electro‐Mechanical Systems (MEMS) switch in the ultrabroadband range from DC to 80 GHz. This proposed RF MEMS switch consists of two arms, with one arm providing a DC loading state (), whereas the second arm provides a capacitive loading state () to the ground when pull‐in voltage is applied. Insertion loss less than 1.85 dB and return loss better than 10 dB are achieved in the OFF state () from DC to 80 GHz (no pull‐in voltage is applied). Due to the novel design topology, this switch can act as a DC‐only switch (0–17 GHz) that provides isolation better than 25 dB during the state. A capacitive‐only switch (48–80 GHz) provides isolation better than 17 dB. This proposed structure can act as either DC(S1) or a capacitive () switch (17–48 GHz) and provides isolation better than 10 dB in either state. This proposed switch finds its best application in reconfigurable circuits like phase shifters due to switching between DC and capacitive loading during the On state from 17 to 48 GHz. The proposed switch's measured pull‐in and lift‐off voltages are 3.5 and 2.85 V, respectively.
Fused deposition modeling for 1 × 2 array of double ridge horn antenna
Authors: You Kok Yeow , Hassan Ahmednur H. , Sim Man Seng , Lee Kim Yee , Cheng Ee Meng , Khe Cheng Seong 
Published: October 2023

AbstractIn this letter, fused deposition modeling (FDM) was used to create a 1 × 2 array of the double ridge horn antenna (DRHA). The material used for FDM was acrylonitrile butadiene styrene. The DRHA was designed using an electromagnetic simulator and printed using FDM as well as the inner surface of the DRHA was painted with silver conducting paint. Two printed DRHA were connected together as a 1 × 2 array via a power divider. The main operating frequency of the array antenna was focussed on the range from 3 to 7 GHz. The 1 × 2 array DRHA is capable of better than −10 dB return loss, greater than 10 dBi gain, and a minimum half‐power bandwidth of 27.5°.
Perception of patient safety culture among nursing students: A cross‐sectional study
Authors: Ramírez‐Torres Carmen Amaia , Rivera‐Sanz Félix , Cobos‐Rincon Ana , Sufrate‐Sorzano Teresa , Juárez‐Vela Raúl , Gea‐Caballero Vicente , Tejada Garrido Clara Isabel , Colado Tello Maria Estela , Durante Angela , Santolalla‐Arnedo Iván 
Published: October 2023

AbstractAimTo analyse the perception of patient safety culture among nursing students and to compare patient safety outcomes between the different year nursing groups.DesignA cross‐sectional descriptive study was conducted with nursing students (n = 266) between first and fourth years from one university in Spain.MethodsThe project was conducted during the 2020/21 academic year. The data were collected using a translated and adapted version of the “Hospital Survey on Patient Safety” developed by the Agency of Healthcare Quality (AHQR).ResultsSignificant differences were found between the year of study of the nursing degree and whether or not specific training in patient safety culture had been received. The nursing students who had received specific training gave scores lower than anyone else in all questionnaire items, but only the indicators of “good practice” (p = 0.00) and “frequency of reported events” (p = 0.0012) showed significant differences. In some cases, fourth‐year students had lower significant mean scores in their “perception of patient safety within unit/sector,” “indicators of good practice” and “total score.”Public ContributionAdverse events related to clinical practice continue to be a global problem. Improvements in patient safety require an increase in the patient safety culture of professionals and the promotion of development facilitators. Clinical practice and specific theoretical training foster greater awareness and demand related to patient safety, which is of interest when it comes to the development of new programmes that combine both methodologies and improve their effectiveness. Patient safety will continue to be a focus for all healthcare systems. The patient safety culture of future healthcare professionals should be developed at the university level in order to avoid unnecessary adverse events.
Adrenergic and mesenchymal signatures are identifiable in cell‐free DNA and correlate with metastatic disease burden in children with neuroblastoma
Authors: Vayani Omar R. , Kaufman Maria E. , Moore Kelley , Chennakesavalu Mohansrinivas , TerHaar Rachel , Chaves Gepoliano , Chlenski Alexandre , He Chuan , Cohn Susan L. , Applebaum Mark A. 
Published: October 2023

AbstractBackgroundCell‐free DNA (cfDNA) profiles of 5‐hydroxymethylcytosine (5‐hmC), an epigenetic marker of open chromatin and active gene expression, are correlated with metastatic disease burden in patients with neuroblastoma. Neuroblastoma tumors are comprised of adrenergic (ADRN) and mesenchymal (MES) cells, and the relative abundance of each in tumor biopsies has prognostic implications. We hypothesized that ADRN and MES‐specific signatures could be quantified in cfDNA 5‐hmC profiles and would augment the detection of metastatic burden in patients with neuroblastoma.MethodsWe previously performed an integrative analysis to identify ADRN and MES‐specific genes (n = 373 and n = 159, respectively). Purified DNA from cell lines was serial diluted with healthy donor cfDNA. Using Gene Set Variation Analysis (GSVA), ADRN and MES signatures were optimized. We then quantified signature scores, and our prior neuroblastoma signature, in cfDNA from 84 samples from 46 high‐risk patients including 21 patients with serial samples.ResultsSamples from patients with higher metastatic burden had increased GSVA scores for both ADRN and MES gene signatures (p < .001). While ADRN and MES signature scores tracked together in serially collected samples, we identified instances of patients with increases in either MES or ADRN score at relapse.ConclusionsWhile it is feasible to identify ADRN and MES signatures using 5‐hmC profiles of cfDNA from neuroblastoma patients and correlate these signatures to metastatic burden, additional data are needed to determine the optimal strategies for clinical implementation. Prospective evaluation in larger cohorts is ongoing.
Assessment and management of anxiety and depression in a pediatric high‐risk asthma clinic
Authors: Averill Samantha H. , McQuillan Maureen E. , Slaven James E. , Weist Andrea D. , Kloepfer Kirsten M. , Krupp Nadia L. 
Published: October 2023

AbstractObjectiveThe aims of this study were to determine the prevalence of positive mental health (MH) screens in a pediatric high‐risk asthma (HRA) clinic population, and to determine the success rate of engagement in MH services before and after adding a clinical psychologist to our multidisciplinary clinic.HypothesisWe hypothesized that the HRA population would have a higher prevalence of anxiety/depression symptoms than that previously reported for the general pediatric asthma population. We anticipated that the presence of an embedded psychologist in HRA clinic would facilitate successful connection to MH services.MethodsPediatric patients in the HRA clinic were prospectively screened for anxiety and depression using validated screening instruments. Positive scores were referred for MH services. Time to MH service engagement was recorded before and after the addition of a clinical psychologist.ResultsA total of 186 patients were screened; 60% had a positive MH screen. Female sex was associated with higher median scores on both screening tools and higher likelihood of engagement in MH services. After addition of a clinical psychologist, new engagement in MH services increased (20% vs. 80%, p < 0.0001), and median time to engagement decreased (14.5 vs. 0.0 months, p = 0.003).ConclusionThere is a high prevalence of anxiety and depression in this pediatric HRA population. Success of engagement in MH services improved after a clinical psychologist joined our multidisciplinary team, suggesting access to care as a primary barrier to engagement.
Working process and opening characteristics of soft insulator of pulse motor
Authors: Bian Yunlong , Shen Zhibin , Li Haiyang , Wu Weijing , Zhang Tao , Wu Guofu , Zhu Hongbing 
Published: October 2023

AbstractIn this paper, a simulation test system for the working process of soft insulation is designed, using equivalent simulated ablation test methods combined with a CCD measuring system and micro electron microscope scanning technology, which can better describe the thermal properties and state of insulation after ablation. At the same time, a test plan for the opening characteristics of the insulator based on different ablation times and different opening structure sizes as the main influencing factors are designed. The experimental results show that the ablation test can well simulate the state of an actual pulse engine compartment after the ablation and the maximum relative error of the ablation rate can be controlled within 5 %. From the influence of ablation time on the opening characteristics of the insulator, it can be seen that the maximum axial deformation of the insulator is different from the relative value of the opening pressure. The radial deformation of the insulator is larger than that of the non‐ablated insulator and larger than the inner diameter of the insulator shell after ablation. From the influence of the size of the opening structure of the insulator (depth of weakening grooves) on the opening characteristics of the insulator, it can be seen that as the weakening groove depth of the compartment deepens, the original pressure change pattern disappears, and the opening pressure and opening time of the insulator decrease significantly.