bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design and Validation of a High-Fidelity Left Atrial Cardiac Simulator for the Study and Advancement of Left Atrial Appendage Occlusion
Authors: Mendez Keegan , Singh Manisha , Willoughby Patrick , Ncho Beatrice , Liao Aileen , Su Susan , Lim Megan , Lee Elijah , Alkhouli Mohamad , Alarouri Hasan , Roche Ellen T. 
Published: January 2025

Abstract

Purpose
Atrial fibrillation (AF) is the most common chronic cardiac arrhythmia that increases the risk of stroke, primarily due to thrombus formation in the left atrial appendage (LAA). Left atrial appendage occlusion (LAAO) devices offer an alternative to oral anticoagulation for stroke prevention. However, the complex and variable anatomy of the LAA presents significant challenges to device design and deployment. Current benchtop models fail to replicate both anatomical variability and physiological hemodynamics, limiting their utility. This study introduces a novel left atrial cardiac simulator that incorporates patient-derived LAA models within a benchtop circulatory flow loop, enabling high-fidelity LAAO device testing and development.

Methods
A rigid, patient-derived left atrium (LA) model was 3D printed from segmented MRI data and modified to accommodate attachment of patient-specific LAA models. A library of LAA geometries was fabricated using silicone casting techniques to replicate the mechanical properties of native tissue. The LA-LAA model was integrated into a circulatory flow loop equipped with a pulsatile pump, pressure sensors, and flow probes, allowing real-time hemodynamic analysis. System tunability was demonstrated by varying heart rate, stroke volume, resistance, and compliance to simulate physiological and pathological conditions.

Results
The simulator accurately replicated LA pressure and flow waveforms, closely approximating physiological conditions. Changes in heart rate, stroke volume, and compliance effectively modulated LAP and LA inflow before and after LAAO. Distinct pressure and flow waveforms were observed with different LAA geometries. Hemodynamic analysis revealed increased left atrial pulse pressure after occlusion, with the greatest increase occurring after complete exclusion of the LAA. The simulator facilitated the evaluation of LAAO device performance, including metrics such as seal and PDL, and served as an effective training tool for iterative device deployment and recapture with visual and imaging-guided feedback.

Conclusions
The left atrial cardiac simulator offers a highly tunable and realistic platform for testing and developing LAAO devices. It also serves as an effective procedural training tool, allowing for the simulation of patient-specific anatomical and hemodynamic conditions. By enabling these advanced simulations, the simulator enhances pre-procedural planning, device sizing, and placement. This innovation represents a significant step toward advancing personalized medicine in atrial fibrillation management and improving LAAO outcomes.
Green companions: Affordances of human–tree relationships
Authors: Vainio Kaisa Kristiina , Takala Tuomo , Limpens Juul , Lummaa Karoliina , Korrensalo Aino , Räsänen Aleksi , Tuittila Eeva-Stiina 
Published: January 2025

Abstract
Trees offer multiple benefits, including impacts on physical and mental health. In this interdisciplinary study, we explored the relationships humans develop with specific favourite trees based on our survey data (n = 158) collected in the Netherlands. Here, we examined action possibilities (affordances) provided by trees, including immaterial actions, such as memorisation or the enjoyment of beauty. We implemented the affordance theory with mixed-method analysis. We identified three distinct types of human-arboreal relationships offering a different variety of action possibilities: nostalgic relationships, nurturing relationships, and empowering relationships. We assume that when humans form relationships with trees, the essence of trees is not their characteristics, but the possibilities for action. We recommend that urban green spaces would support interactions between humans and trees. By strengthening our connectedness with nature, it is possible to promote both human well-being and to strengthen environmentally responsible values and behaviours.
Investigating seafarers’ perceptions of well-being onboard: do company size and vessel type matter?
Authors: Karakasnaki Maria , Polemis Dionysios , Gerou Anastasia 
Published: January 2025

Abstract
Throughout the last few years, the maritime sector has recognized the significance of strengthening seafarers’ well-being to ensure safe transportation services of high quality. The population of seafarers is quite heterogeneous regarding demographics and other working characteristics. Even though seafarers’ well-being is at the core of the academic agenda, company-specific factors associated with their well-being perceptions remain quite under-investigated. The current study aims to examine whether seafarers’ perceptions of their well-being are associated with the size of the company, which they work for, and with the vessel type of their employment. An empirical survey was performed on a sample of 872 seafarers and the data were analyzed through confirmatory factor analysis and analysis of variance. According to the findings, it seems that company size (i.e., small, medium, and large/ very large) is associated with well-being perceptions (conceptualized as a multidimensional construct comprising the physical dimension, functional dimension, healthy dimension, communication and cultural dimension). However, these perceptions do not seem to be linked with the vessel type of seafarers’ employment (containerships, dry bulk carriers, tankers). The current study attempts to contribute to the literature that associates company-specific characteristics with employees’ perceptions and adds new knowledge to the maritime transportation literature regarding the understanding of the link between company-specific factors and seafarers’ well-being.
ADIIT — An Evidence-Based Maturity Model for Faculty Support Teams in the Health Professions
Authors: Kurzweil Dina , Marcellas Karen , Macaulay Linda S. 
Published: January 2025

Abstract
Faculty support teams in health professions education operate in a unique environment that can engender specific challenges in their operations and development. This paper introduces an evidence-based maturity model designed to support the establishment and growth of such teams. The ADIIT model, which is named for the five levels of maturity that such teams can attain: (1) Ad Hoc/Initial; (2) Defined; (3) Integrated; (4) Innovative; (5) Transformative, enables faculty support teams to assess their current state and identify areas for improvement. Key elements of performance included in the model are team, leadership, operations/focus, customer base, and auxiliary services. The paper describes criteria for each element at each level and provides guidance about how to advance to the next level. A fictional case study is provided to demonstrate the application of the maturity model. Using this model will help faculty support teams in health professions education to develop the high level of focus and professionalism necessary to navigate between and provide support for classroom education, distributed learning, and clinical education.
NH4+-Modulated Cathodic Interfacial Spatial Charge Redistribution for High-Performance Dual-Ion Capacitors
Authors: Chen Yumin , Song Ziyang , Lv Yaokang , Gan Lihua , Liu Mingxian 
Published: January 2025

Abstract
Compared with Zn2+, the current mainly reported charge carrier for zinc hybrid capacitors, small-hydrated-sized and light-weight NH4
+ is expected as a better one to mediate cathodic interfacial electrochemical behaviors, yet has not been unraveled. Here we propose an NH4
+-modulated cationic solvation strategy to optimize cathodic spatial charge distribution and achieve dynamic Zn2+/NH4
+ co-storage for boosting Zinc hybrid capacitors. Owing to the hierarchical cationic solvated structure in hybrid Zn(CF3SO3)2–NH4CF3SO3 electrolyte, high-reactive Zn2+ and small-hydrate-sized NH4(H2O)4
+ induce cathodic interfacial Helmholtz plane reconfiguration, thus effectively enhancing the spatial charge density to activate 20% capacity enhancement. Furthermore, cathodic interfacial adsorbed hydrated NH4
+ ions afford high-kinetics and ultrastable C‧‧‧H (NH4
+) charge storage process due to a much lower desolvation energy barrier compared with heavy and rigid Zn(H2O)6
2+ (5.81 vs. 14.90 eV). Consequently, physical uptake and multielectron redox of Zn2+/NH4
+ in carbon cathode enable the zinc capacitor to deliver high capacity (240 mAh g−1 at 0.5 A g−1), large-current tolerance (130 mAh g−1 at 50 A g−1) and ultralong lifespan (400,000 cycles). This study gives new insights into the design of cathode–electrolyte interfaces toward advanced zinc-based energy storage.
Pathogens threatening agriculture and biodiversity in South Africa: A horizon scanning approach
Authors: Tshikhudo Phumudzo P. , Rambauli Maanda , Mnguni Simphiwe , Nnzeru Livhuwani R. , Mulabisana Julia , Cruywagen Elsie M. , Sutherland Rene , Munyai Thinandavha C. 
Published: January 2025

Abstract
There is mounting evidence that invasive alien species (IAS) have adverse effects on plant health and the global economy, posing a significant threat to biodiversity and ecosystem functioning. Identifying and assessing emerging IAS, such as plant pathogens, is a proactive approach that might assist in prioritising potential pathogen threats before they become established or widespread, negatively affecting plant health, crop production, animal production, animal health by affecting pastures and food security in South Africa. We collected information from the CABI Invasive Species Compendium and Crop Protection Compendium on plant pathogens that are present in neighbouring countries and are likely to be introduced throughout the Republic of South Africa using an expert-elicitation horizon scanning study. Pathogens with the highest score were determined based on their strong capability on the chance of entry, establishment, economic impact, and biodiversity destruction. The current study revealed that only 17 pathogens (6 fungi, 7 viruses, 2 bacteria and 2 phytoplasma) had been prioritised due to their potential to enter the country and have been reported in the neighbouring countries. Maize lethal necrosis disease, Candidatus Liberibacter asiaticus
,
Candidatus Phytoplasma palmae, Fusarium oxysporum f.sp. cubense tropical race 4, and Maize chlorotic mottle virus have the highest potential to enter and establish in the country. The most effective phytosanitary actions for the high scoring pathogen were to conduct surveillance for their potential presence in South Africa and risk analysis, especially for organisms recorded in neighbouring countries.
Salvage-Operationen beim Prostatakarzinomrezidiv
Authors: Padevit Christian 
Published: January 2025

Zusammenfassung
Seitdem die PSMA-PET („prostate-specific membrane antigen positron emission tomography“) zur Verfügung steht, konnten differenzierte Therapiekonzepte für die Rezidivsituation nach radikaler Prostatektomie entwickelt werden. Davor war nur die frühzeitige Salvage-Radiotherapie beim vermuteten Lokalrezidiv möglich oder gar eine systemische Therapie mittels Androgendeprivation. Heutzutage können lokale Salvage-Behandlungen in Form von Resektion oder Bestrahlung von Lymphknotenmetastasen erfolgen, um damit die Notwendigkeit einer medikamentösen Therapie zu verzögern. Das beste Outcome konnte bei Patienten mit unilateralem Befall von Lymphknoten im kleinen Becken beobachtet werden. Einen kompletten PSA-Abfall kann mittlerweile bei bis zu 80 % aller operierten Patienten erreicht werden, im Schnitt beträgt die mittlere rezidivfreie Zeit 8 Monate. Bei einem gut selektionierten Patientengut kann eine Salvage-Prostatektomie bei lokalem Tumorrezidiv in Betracht gezogen werden.
Explicit Synchronized Solitary Waves for Some Models for the Interaction of Long and Short Waves in Dispersive Media
Authors: Brewer Bruce , Liu Chuangye , Nguyen Nghiem V. 
Published: January 2025

Abstract
A system coupling the cubic, nonlinear Schrodinger equation (NLS) and the Korteweg–de Vries equation (KdV) commonly known as the NLS–KdV system was previously analysed to be inconsistently derived and a few alternative systems were proposed as more suitable models for describing the interaction of long and short waves in dispersive media (Deconinck et al. in J Phys A: Math Theor 49:415501, 2016. https://doi.org/10.1088/1751-8113/49/41/415501; Nguyen and Liu in Water Waves 2:327–359, 2020. https://doi.org/10.1007/s42286-020-00038-6; Commun Math Sci 21(3):641–669, 2023. https://doi.org/10.4310/CMS.2023.v21.n3.a3). In this manuscript, these alternative systems are shown to possess synchronized solitary waves via the method of constrained minimization, as well as by direct computation of the associated systems of ODEs. These synchronized solitary waves have the hyperbolic

$$\textrm{sech}^2$$

sech
2

-profile typical of dispersive equations.
Hands-On Mastery in Physiological Signal Processing: A Challenge-Based Learning Approach
Authors: Barquero-Pérez Óscar , Cámara-Vázquez Miguel Ángel , Goya-Esteban Rebeca 
Published: January 2025

Abstract

Purpose
Teaching and learning statistical signal processing in Biomedical Engineering Degrees poses challenges for both students and teachers. Students often perceive signal processing subjects as demanding and somewhat unattractive, with failure rates several times higher than that of other courses. The aim of this work is to address the following question: Are competitions that present real physiological signal processing problems an effective way to teach the practical skills needed in statistical signal processing?

Methods
We propose to use a problem-driven activity in which students form groups of two or three students and enter a Kaggle-type competition during the whole semester. The competition consists of a real physiological signal problem along with well-defined metrics to establish the performance of the solutions. We measure the effectiveness of the activity with questionnaires together with sentiment and inductive coding analysis that allows evaluation of the acquisition of competencies.

Results
According to the results obtained in four consecutive editions, students find the challenge to be a better means than traditional laboratory practices for acquiring practical skills, as well as allowing them to better understand theoretical concepts. Students found the activity challenging and demanding but one of the best activities in the whole degree, since it brings the student closer to real practice as biomedical engineers.

Conclusion
The results support the hypothesis that this type of competition allows students to gain a deeper understanding of the practical aspects of physiological signal processing courses.
From Benefit–Cost Analysis to Social Welfare: A Pragmatic Approach
Authors: Ferranna Maddalena , Hammitt James K. , Robinson Lisa A. 
Published: January 2025

Abstract
Conventional benefit–cost analysis is well-established and widely used to assess interventions designed to improve public health and welfare. While it has many advantages, it has well-known limitations. Chief among these is its inattention to the distributional equity of the impacts. To measure individual well-being, the conventional approach relies on individuals’ willingness to exchange their own income for the outcomes they experience. To measure societal welfare, it relies on simple aggregation of these values across individuals. This approach reflects a relatively narrow conception of welfare and ignores how impacts are distributed across advantaged and disadvantaged individuals. Social welfare analysis has been proposed as an alternative approach to address these limitations, but real-world applications are rare due largely to the complexity of the calculations. This article provides a pragmatic approach for conducting equity-sensitive benefit–cost analysis globally that addresses data limitations and other challenges, illustrated with example applications. It formally develops and implements equity weights that adjust for the decreasing marginal value of money and for additional moral considerations, prioritizing increases in welfare for those who are worse off.
Trajectories and Influencing Factors of Post-Traumatic Stress in Disaster-Affected People According to Their Income Level: A Longitudinal Study in South Korea
Authors: Lee Yubin , You Myoungsoon 
Published: January 2025

Abstract

Objective
Disasters often have long-lasting effects on the mental health of people affected by them. This study aimed to examine the trajectories and predictors of mental health in people affected by disasters according to their income level.

Method
This study used data from the “Long-Term Survey on the Change of Life of Disaster Victim” conducted by the National Disaster Management Research Institute. Latent growth curve modeling and multigroup analysis were employed on 699 participants.

Results
Individuals in the low-income class had a higher post-traumatic stress (PTS) intercept than those in the middle-high-income class. The PTS intercept was increased by unmet health care needs and financial hardship caused by disasters and was decreased by health care support. Social support, which was low in the low-income class, did not affect their PTS level; however, it lowered the PTS intercept in the middle-high-income class.

Conclusions
These results suggest that it is important to address the mental health of disaster survivors by providing sufficient disaster relief services and compensation to ensure that disasters do not further exacerbate social inequalities. It is also crucial to provide emotional, informational, and material support using local community resources for those who have less or no access to in-person social networks.
A reply to Komárek
Authors: Somek Alexander , Paar Elisabeth 
Published: January 2025

AbstractThis is a reply to Komárek’s criticism of our article “Europe’s political constitution”. We address the issues raised by our critic one by one. The topics range from the definition of the public sphere to the role that law blogs and social media play in it. The reply concludes by examining what it means to pursue truth in legal scholarship based on contrasting the views of Hans Kelsen und Stanley Fish.
From SSI to contextualism
Authors: Langford Simon 
Published: January 2025

Abstract
Subject-Sensitive Invariantism (SSI) and Epistemic Contextualism (EC) are rival theories in epistemology. Both involve shifting epistemic standards, but they differ in how they explain this shiftiness. SSI is primarily a metaphysical thesis about the knowledge relation, whereas EC is primarily a semantic thesis about knowledge attributions. This paper revisits some of the central problems faced by SSI, especially those concerning Dutch books and third-person knowledge ascriptions. The main aim is to show that existing responses that stay true to SSI do not succeed, leaving SSI in serious jeopardy. Some strategies put forward by, or on behalf of, SSI-friendly philosophers fare better. But these involve forsaking central features of SSI, ceding ground to EC, and falling back on a defense of impurism. I sketch what such an impurist fallback position might look like and argue that the more ground it cedes to EC, the more attractive it will be. It is shown that such an impurist, contextualist position can handle all the difficulties I discuss in relation to SSI. The paper concludes by briefly considering what new challenges this kind of position faces instead.
Navigating the blood–brain barrier: enhancing blood culture practices in the neuro-ICU
Authors: Metz Maureen , Colton Katharine , Seidelman Jessica 
Published: January 2025

Abstract
This study evaluates the implementation of a blood culture (BCx) algorithm in the neurology ICU (NICU) to reduce BCx event (BCE) rates. Results show a reduction in BCE rates, without increasing adverse outcomes. The findings support the feasibility of BCx algorithms for improving diagnostic stewardship in the specialized NICU population.
Facilitators of antibiotic decision-making in home-based primary care: a qualitative investigation
Authors: Datta Rupak , Kiwak Eliza , Fried Terri , Benjamin Andrea , Iannone Lynne , Krein Sarah , Carter Warren , Cohen Andrew 
Published: January 2025

Abstract
Interviews with 22 home-based primary care (HBPC) clinicians revealed that infectious disease physicians and clinical pharmacists facilitate infection management and antibiotic selection, respectively, and that local initiatives within programs support antibiotic prescribing decisions. Interventions that facilitate specialist engagement and tailored approaches that address the unique challenges of HBPC are needed.
A bridge over troubled water: reverse osmosis to maintain patient care in a boil water notice
Authors: Smith Jacob , Fischer Julia , Mathew Manju , Haessler Sarah 
Published: January 2025

Abstract
A citywide boil water notice necessitated an alternative solution for treating contaminated water. We report our experience using portable reverse osmosis machines to treat the municipal water to provide purified water to patient care areas where non-sterile water was needed, preventing interruptions in services like elective surgeries.
ON THE BURES METRIC,
$C^*$
-NORM AND QUANTUM METRIC
Authors: AGUILAR KONRAD , BEHERA KARINA , OMLAND TRON , WU NICOLE 
Published: January 2025

Abstract
Given a unital

$C^*$

-algebra and a faithful trace, we prove that the topology on the associated density space induced by the

$C^*$

-norm is finer than the Bures metric topology. We also provide an example when this containment is strict. Next, we provide a metric on the density space induced by a quantum metric in the sense of Rieffel and prove that the induced topology is the same as the topology induced by the Bures metric and

$C^*$

-norm when the

$C^*$

-algebra is assumed to be finite dimensional. Finally, we provide an example where the Bures metric and induced quantum metric are not metric equivalent. Thus, we provide a bridge between these aspects of quantum information theory and noncommutative metric geometry.
A southernmost record of the Pacific black scabbardfish Aphanopus arigato (Scombriformes, Trichiuridae) from the South China Sea
Authors: Lin Yen-Ting , Lin Chien-Hsiang , Han Yu-San 
Published: January 2025

Abstract
In this study, a single specimen of Pacific black scabbardfish Aphanopus arigato Parin, 1994 was collected at a depth of ~500 m near Dongsha Island in southwestern Taiwan (18°49′ to 20°45′N and 112°46′ to 116°15′E), on 14 March 2023. This is the southernmost record of A. arigato, with a significantly wide range extension from northern Japan, and southern Kuril Islands to the South China Sea. We also provide comparisons of the morphological measurements, first description of sagittae otoliths, and a partial sequence of the cytochrome oxidase subunit I gene for the specimen studied in this study.