bluuebunny/crossref_metadata_2025_split huggingface dataset:
Association of part-time clinical work with well-being and mental health in General Internal Medicine: A survey among Swiss hospitalists
Authors: Bretagne Lisa , Mosimann Stefanie , Roten Christine , Perrig Martin , Genné Daniel , Essig Manfred , Mancinetti Marco , Méan Marie , Darbellay Farhoumand Pauline , Huber Lars C. , Weber Elisabeth , Knoblauch Christoph , Schoenenberger Andreas W. , Frick Sonia , Wenemoser Eliane , Ernst Daniel , Bodmer Michael , Aujesky Drahomir , Baumgartner Christine 
Published: September 2023

Introduction
Burnout and low job satisfaction are increasing among the General Internal Medicine (GIM) workforce. Whether part-time compared to full-time clinical employment is associated with better wellbeing, job satisfaction and health among hospitalists remains unclear.

Materials and methods
We conducted an anonymized cross-sectional survey among board-certified general internists (i.e. hospitalists) from GIM departments in 14 Swiss hospitals. Part-time clinical work was defined as employment of <100% as a clinician. The primary outcome was well-being, as measured by the extended Physician Well-Being Index (ePWBI), an ePWBI ≥3 indicating poor wellbeing. Secondary outcomes included depressive symptoms, mental and physical health, and job satisfaction. We compared outcomes in part-time and full time workers using propensity score-adjusted multivariate regression models.

Results
Of 199 hospitalists invited, 137 (69%) responded to the survey, and 124 were eligible for analysis (57 full-time and 67 part-time clinicians). Full-time clinicians were more likely to have poor wellbeing compared to part-time clinicians (ePWBI ≥3 54% vs. 31%, p = 0.012). Part-time compared to full-time clinical work was associated with a lower risk of poor well-being in adjusted analyses (odds ratio 0.20, 95% confidence interval 0.07–0.59, p = 0.004). Compared to full-time clinicians, there were fewer depressive symptoms (3% vs. 18%, p = 0.006), and mental health was better (mean SF-8 Mental Component Summary score 47.2 vs. 43.2, p = 0.028) in part-time clinicians, without significant differences in physical health and job satisfaction.

Conclusions
Full-time clinical hospitalists in GIM have a high risk of poor well-being. Part-time compared to full-time clinical work is associated with better well-being and mental health, and fewer depressive symptoms.
Using laboratory data to assess the impact of coronavirus (COVID-19) on reflex cryptococcal antigenaemia (CrAg) testing in South Africa
Authors: Cassim Naseem , Coetzee Lindi Marie , da Silva Manuel Pedro , Stevens Wendy Susan , Glencross Deborah Kim 
Published: September 2023

Background
Coronavirus disease (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), was first reported in Wuhan, China. Due to the rapid spread globally, it was declared a pandemic in March 2020. Social distancing and lockdown measures were introduced to limit transmission. These strategies could potentially impact the diagnosis and treatment of patients with advanced HIV who are susceptible to secondary infections like cryptococcal disease. In South Africa, reflexed cryptococcal antigenaemia (CrAg) testing and pre-emptive antifungal treatment are recommended preceding antiretroviral therapy initiation for patients with a CD4<100 cells/μl. This study aimed to assess the impact of COVID-19 on CrAg testing in South Africa.

Methods
Specimen-level data was extracted for individuals ≥15 years from the National Health Laboratory Services repository for calendar years 2018 to 2021. Test volumes and CrAg positivity were assessed at national and provincial levels, by age category and gender. The percentage change in annual and monthly CrAg test volumes for 2020 and 2021 (during lockdown levels) are compared to data reported for 2018. The monthly median CD4 and the percentage of samples with a count <25, 25–50, 51–75 and >75-<100 cells/μl were assessed.

Results
Specimen data of 11 944 929 CD4 results included 1 306 456 CrAg tests. Annual CD4 and CrAg test volumes declined by 22.4% and 27.8% for 2020 and 2021 respectively (relative to 2018). There were 23 670 CrAg positive outcomes in 2018 compared to 21 399 (-9.6%) and 17 847 (-24.6%) in 2020 and 2021 respectively. A monthly test volume reduction of up to 36.6%, 35.5%, 36.1% and 13.3% was reported for infection waves one to four. CrAg detection increased from 6.3% in 2018 to 7.5% in 2020. More testing was offered to males (>56%) with a higher detection rate of 8.1% in 2020. Between 81.0% and 81.8% of testing was for patients aged 20 to 49 years. The monthly percentage of specimens <25 cells/μl ranged from 30.2% (June 2019) to 35.3% (August 2020). Overall, the monthly median CD4 ranged from 39 (IQR: 15–70)(August 2020) to 45 (IQR: 19–72)(March 2019) cells/μl. In 2020, the provincial percentage change in CrAg test volumes ranged from 2.9% to -33.7%.

Conclusion
Our findings confirmed the impact of lockdown measures on both the absolute number of CrAg tests performed and detection (increase in 2020). A smaller impact on the median CD4 was noted. The long-term impact on patient management in immune- compromised individuals needs further investigation.
Introducing a novel and natural antibiotic for the treatment of oral pathogens: Abelmoschus esculentus green-formulated silver nanoparticles
Authors: Nie Tinghong , Liu Geng , Xiao Yunhe , Yari Hadis , Goorani Samaneh 
Published: September 2023

Abstract
Nanotechnology can solve many biomedical problems and cause transformation in the field of health and pharmaceuticals. The use of this technology in removing pathogenic bacteria is of great interest. The introduction of a strong antibacterial agent is very important to control pathogenic bacteria, especially strains resistant to antibiotics. The aim of this research was to synthesize silver nanoparticles (AgNPs) with the help of Abelmoschus esculentus aqueous extract and investigate its antibacterial properties against oral pathogens. Our study examined the ability of AgNPs to inhibit the dental bacterial growth and anti-adherence in vitro. The biosynthesized AgNPs@Abelmoschus esculentus were characterized by FT-IR, UV–Vis, and SEM tests. The physical and chemical investigation of the synthesized AgNPs showed that the particles were produced in nano dimensions, spherical shape, and without any impurities. In antibacterial test, the 8 µg/mL exhibited the lowest minimum inhibitory concentrations (MICs) against Porphyromonas gingivalis and Streptococcus mutans (MIC = 8 µg/mL). In vitro adherence of S. mutans was significantly prevented by AgNPs@Abelmoschus esculentus (MIC = 8–16 µg/mL). According to the results, the AgNPs@Abelmoschus esculentus may be good candidates for the oral hygiene agents to prevent periodontopathic conditions and dental caries.
Exploring Mutual Learning of Four Chinese Senior High School EFL Teachers in a Collaborative Action Research Community
Authors: Zheng Hongying , Huan Tingting 
Published: September 2023

Abstract
English as a Foreign Language (EFL) teachers’ professional development has been attached much importance with the advent of the National English Curriculum Standards (NECS in short) for Senior High Schools as it initiates the shift from knowledge-skill-oriented education to competence-oriented education. As an effective way for teachers’ professional development, collaborative action research community is introduced in this study to provide teachers with opportunities for mutual engagement, meaning negotiation, and a shared repertoire. Four senior high school EFL teachers from four different schools were studied in a collaborative action research community to explore how teachers from diversified backgrounds achieve mutual learning for their professional development. With data collected from observation, interviews, and journals, the study reveals that diversity and partiality help maintain mutual engagement in the community of practice. Meaning negotiation and mutual accountability in a joint enterprise contribute to the coherence of the community. Moreover, the participative activity of online and offline group discussion and the common topic of thinking visualization were treated as sources of a shared repertoire, an essential indication of a harmonious community. In this case, this study extrapolates how the collaborative action research community achieves harmony to support teachers’ professional development in action research.
Rebuilding Authority in “Lumpen” Communities: The Need for Basic Income to Foster Entitlement
Authors: Johnson Matthew Thomas 
Published: September 2023

Abstract
This article presents an immanent critique of neoliberal welfare reform using observation of participatory research involving left-behind communities in the North East of England and Australia. It argues that harms, such as passivity, invoked to reduce social security and increase conditionality are actually enhanced by austerity, conditionality and philanthropic giving. Deploying Mauss’ conception of the gift suggests that aggressive, conditional giving, combined with consumption through indebtedness, has served to strip individuals of authority. This leads to a radical conclusion: the stated aims of policy platforms like Big Society can only be realized through statutory entitlements like basic income.
Short Selling, COVID-19 and the Regulators – Lessons Learned
Authors: Sieder Sebastian 
Published: September 2023

Abstract

385Some national competent authorities (NCAs), as well as ESMA, have responded with short-selling bans and other restrictions to the COVID-19 pandemic. This approach has attracted criticism in both legal and economic literature. Although the COVID-19 pandemic has been overcome, or at least ways of dealing with COVID-19 have been found, it is of crucial importance for future EU short selling regulation how the legal basis of the measures for exceptional situations is designed and how the supervisory authorities will deal with it. This is valid not least because we are living in a time in which one crisis (COVID-19) follows the next (Ukraine war, gas shortage, inflation etc). Against this backdrop, this paper reviews the academic assessment of the supervisory approach taken and aims to contribute to an improved legislative and supervisory approach regarding short selling in (future) crises.386
Trial protocol: Feasibility of neuromodulation with connectivity-guided intermittent theta-burst stimulation for improving cognition in multiple sclerosis
Authors: Blanchard Caroline , De Dios Perez Blanca , Tindall Tierney , Clarkson Katie , Felmban Ghadah , Scheffler-Ansari Grit , Periam Roger , Lankappa Sudheer , Constantinescu Cris S. , das Nair Roshan , Morriss Richard , Evangelou Nikos , Auer Dorothee P. , Dineen Rob A. 
Published: September 2023

Abstract
Cognitive impairment in multiple sclerosis (MS) can adversely impact participation in employment, activities of daily living, and wider society. It affects 40–70% of people living with MS (pwMS). There are few effective treatments for cognitive impairment in people with MS. Neuromodulation with intermittent theta-burst stimulation (iTBS) has potential for treating cognitive impairment in pwMS. This single-centre mixed-methods feasibility randomised controlled trial (NCT04931953) will assess feasibility, acceptability, and tolerability of procedures used for applying iTBS for improving cognitive performance in pwMS. Participants will be randomised into three intervention groups with varying lengths of iTBS treatment (from 1 to 4 weeks) and a sham-control group. Quantitative data will be collected at three time points (baseline, end of intervention, and 8-week follow-up). End of the intervention semi-structured interviews will explore the views and experiences of the participants receiving the intervention, analysed using framework analysis. Quantitative and qualitative data will be synthesised to explore the impact of the iTBS intervention. Ethical approval has been received from the Health Research Authority (21/LO/0506) and recruitment started in June 2022. The results will inform the design of an RCT of the efficacy of iTBS as a therapeutic intervention for cognitive impairment in pwMS.
Synthesis, structure, and luminescence properties of double perovskites Ba2.9Sr0.1WO6: Eu3+ red emitting phosphor
Authors: Ullah Arif , Zhuang Jinghao , Liu Zheng , Yang Xiaozhan , Feng Wenlin 
Published: September 2023

Abstract
In this work, the phosphors of Eu3+ ions doped Ba2.9Sr0.1WO6 were successfully synthesized by the high-temperature solid-state method. The luminescence properties, including the emission and excitation spectra, fluorescent lifetimes, and CIE chromaticity coordinates were characterized. The crystal structure and composite of the samples were investigated by XRD (X-ray diffraction), and HRTEM (high-resolution transmission electron microscope). The emission spectra consist of the characteristic peak of Eu3+ excitation at 393 nm; the leading emission peak at 618 nm can be ascribed to the transition of 7F0 → 5L6. The optimal red emission is achieved by 2 % Eu3+ doping. This red Ba2.9Sr0.1WO6: Eu3+ has good luminescent properties and may have potential application in white LEDs.
Nuevos usos para viejas formas: el caso de cualmente en judeoespañol
Authors: García Moreno Aitor 
Published: September 2023

Abstract
Sephardic texts show a wide variety of adverbial forms ending in -mente, where the etymological scheme of adjective (fem.-sing.) + -mente has been broadened with formations such as verdadmente (‘truly’) or cercamente (‘closely’), in which the suffix -mente is attached (respectively) to a nominal and an adverbial base to form new adverbs of mode/manner. Now, the form cualmente deserves a whole new chapter. Thus, as it has been shown so far (García Moreno 2004, 264‒265, and Hernández González 2012, 196‒197, and 2018), this form of original adverbial character – with a similar meaning to that of its parallel talmente – shows in Judeo-Spanish a process of grammaticalization that has led it to function as a conjunction to introduce completive subordinate clauses.Having said that, such conjunctive uses – mainly documented in Sephardic texts of the so-called «rabbinical prose» of the 18th and 19th centuries – are practically absent in more modern texts. However, as we have demonstrated in this contribution, the form cualmente appears again reanalyzed in journalistic texts from the 1930 s as a type of a relative adverb with a value equivalent to that of ʻaccording to whichʼ and agglutinating the values +relative and +manner of their respective formants cual and -mente.
L’amore coniugale nella tradizione lirica femminile oitanica: persistenze e discontinuità nelle Autres Balades di Christine de Pizan1
Authors: Tornatore Lidia 
Published: September 2023

Abstract
Marital love is one of the major themes in medieval French literature. The paper aims to investigate this theme in Christine de Pizan’s heterogeneous collection of poems entitled Autres Balades. In particular, this contribution proposes a critical edition of two Ballads, namely No. 8 (Dieux! On se plaint trop durement) and No. 26 (Doulce chose est que mariage). The results of the study show the persistence of the theme in the female lyric tradition. Moreover, the resulting commentary reveals important influences of the Old French chansons de malmariée on Christine de Pizan’s Ballads.
Compressive Flow Behavior and Microstructural Evolution of Friction Stir Processed A356-5% B4C Composite
Authors: Gangolu S. , Sabirov I. , Gourav Rao A. , Prabhu N. , Kashyap B. P. 
Published: September 2023

Abstract
An Al-7Si-0.3Mg (A356) alloy reinforced with 5 % boron carbide (B4C) particulates was produced through squeeze casting technique at a temperature of 710°C. Friction stir processing (FSP) was employed on an A356-5% B4C composite with optimized parameters, viz., tool advancing speed of 15 mm/min and tool rotation speed of 250 r/min for one pass and two passes. High-temperature flow behavior of the FSPed A356-5% B4C composite was investigated by strain rate jump (1 × 10−3 to 5 × 10−1 s−1) compression tests using a thermomechanical simulator at temperatures of 470°C and 500°C. Strain rate jump tests revealed superplastic region with strain rate sensitivity index m = 0.4 in the lower strain rate regime of 1 × 10−3 to 5 × 10−2 s−1. However, the value of m reduced to 0.3 upon two-pass FSP. The reduction in m is attributed to the more uniform redistribution of hard Si particles throughout the composite, as examined by microstructure evolution in scanning electron microscopy, linked with energy-dispersive spectroscopy and electron-backscattered diffraction facility.
ENTRE A HISTÓRIA E A MEMÓRIA:
Authors: Fraga Pereira Franciele , Duarte Leon Adriana 
Published: September 2023

O presente estudo analisa o Curso Técnico em Edificações, do IFSul Campus Jaguarão. A metodologia pautou-se na pesquisa qualitativa e utilizou da análise documental e do contato com os egressos para compreensão da problemática estabelecida. Os resultados do trabalho corroboram com a incumbência firmada entre instituto e comunidade local de formar profissionais sensíveis à temática do patrimônio cultural, demanda estabelecida pela população em audiências públicas prévias à instalação do Campus na cidade.
Continuous glucose monitoring in a patient with insulinoma presenting with unawareness of postprandial hypoglycemia
Authors: Nakajima Rikako , Idesawa Hiroto , Sato Daisuke , Ito Jun , Ito Kei , Fujii Masanao , Suzuki Takamichi , Furuta Tomoaki , Kawai Hitomi , Takayashiki Norio , Kurata Masanao , Yagyu Hiroaki 
Published: September 2023

Summary
Unawareness of postprandial hypoglycemia for 5 years was identified in a 66-year-old man at a local clinic. The patient was referred to our hospital because of this first awareness of hypoglycemia (i.e. lightheadedness and impaired consciousness) developing after lunch. In a 75 g oral glucose tolerance test, the plasma glucose concentration was decreased to 32 mg/dL (1.8 mmol/L) at 150 min with relatively high concentrations of insulin (8.1 μU/mL), proinsulin (70.3 pmol/L), and C-peptide (4.63 ng/mL). In a prolonged fasting test, the plasma glucose concentration was decreased to 43 mg/dL (2.4 mmol/L) at 66 h with an insulin concentration of 1.4 μU/mL and a C-peptide concentration of 0.49 ng/mL. Computed tomography showed an 18 mm hyperenhancing tumor in the uncinate process of the pancreas. A selective arterial calcium stimulation test showed an elevated serum insulin concentration in the superior mesenteric artery. The patient was then diagnosed with insulinoma and received pancreaticoduodenectomy. Continuous glucose monitoring (CGM) using the Dexcom G6 system showed unawareness of hypoglycemia mainly during the daytime before surgery. When the sensor glucose value was reduced to 55 mg/dL (3.1 mmol/L), the Dexcom G6 system emitted an urgent low glucose alarm to the patient four times for 10 days. Two months after surgery, an overall increase in daily blood glucose concentrations and resolution of hypoglycemia were shown by CGM. We report a case of insulinoma with unawareness of postprandial hypoglycemia in the patient. The Dexcom G6 system was helpful for assessing preoperative hypoglycemia and for evaluating outcomes of treatment by surgery.

Learning points

Insulinoma occasionally leads to postprandial hypoglycemia.

The CGM system is useful for revealing the presence of unnoticed hypoglycemia and for evaluating treatment outcomes after surgical resection.

The Dexcom G6 system has an urgent low glucose alarm, making it particularly suitable for patients who are unaware of hypoglycemia.
Effect of COVID-19 Pandemic on Hepatocellular Carcinoma Diagnosis: Results from a Single Turkey Center Study
Authors: Bilican Gülden , Özgül Seçkin , Ekmen Nergiz , Moral Kenan , Küçük Harun , Dumanlı Serkan , Abiyev Azer , Karakan Tarkan , Kekilli Murat 
Published: September 2023

Background and Aims: Currently malignancies of the liver are the sixth most frequently diagnosed cancers worldwide. The admission of patients to hospitals decreased due to the restriction of the Coronavirus disease 2019 (COVİD-19) pandemic, especially patients suspected with cancer were delayed in their diagnosis and treatment. With this study, we aimed to investigate whether the Covid-19 pandemic caused a decrease in the number of hepatocellular cancers (HCC) or a delay in its diagnosis.
Methods: The study, which included newly diagnosed HCC patients, was conducted as a retrospective cross sectional study, in a single Turkey medical center. The patients were divided into pre-COVID-19 and post- COVID-19 two-year periods and compared in terms of tumor size, biochemical parameters, clinical and demographic features.
Results: A total of 63 HCC patients, 46 (73%) patients before the COVID-19 pandemic and 17 (27%) patients diagnosed during the COVID-19 pandemic were included. Maximum diameter of lesions and serum alpha- fetoprotein levels showed a statistically significant difference between the groups. Maximum tumor size in the pre-COVID-19 period was 4.58±3.77 mm, while in the COVID-19 period was 7.42±6.88 mm, the difference between two groups being statistically significant (p<0.05). HCC in the pre-COVID-19 period were detected mostly at Barcelona Clinic for Liver Cancer (BCLC) stage A (45.7%, n=21), while in the COVID-19 period most of HCC were detected at stage B (35.3%, n=6).
Conclusions: The COVID-19 pandemic limited the access of patients to screening programs for HCC. The significant disruption in screening cirrhotic patients for HCC has led to a delay in diagnosis.
Frequency and Related Risk Factors of Refeeding Hypophosphatemia in Patients with Liver Cirrhosis: A Pilot Study
Authors: Can Sezgin Gulten , Ozer Nurhayat Tugra , Sahin Gulsah Gunes , Sahin Serap , Yurci Mustafa Alper , Guven Kadri , Gundogan Kursat 
Published: September 2023

Background and Aim: Refeeding hypophosphatemia (RH) is associated with poor clinical outcomes and mortality. The presence of RH in patients with liver cirrhosis remains unclear. This study aims to determine the frequency of RH related to nutritional status and disease severity in liver cirrhosis.
Methods: This study was prospectively conducted in a-single center gastroenterology clinic. Malnutrition was identified by Subjective Global Assessment (SGA). The disease severity was defined using Child score and MELD score. Serum phosphate levels <2.0 mg/dl are defined as hypophosphatemia.
Results: Twelve of 50 cirrhotic patients (24%) had RH during hospitalization. The most common RH was determined in 4 patients on day 4 during study follow up. The sharpest decline of serum phosphate levels was on day 4 (median: 2.3mg/dL). The Child score and MELD score were not significantly different between RH and Non-RH groups (p>0.05). The rate of malnutrition according to SGA was 56.0%. A total of 82%, 4%, 8%, and 4% of participants received regular diet and oral nutritional supplements, only enteral tube feeding, only parenteral nutrition, and combined enteral and parenteral nutrition, respectively. In the RH group, 32% of participants received only parenteral nutrition and had a higher presence of RH than patients receiving only oral or enteral tube feding (p<0.05).
Conclusions: RH developed in ¼ of the study participants. This study also showed that artificial feeding carries a significant risk in terms of RH. Malnourished patients with liver cirrhosis receiving parenteral nutrition, closely monitored regarding high risk of RH.