bluuebunny/crossref_metadata_2025_split huggingface dataset:
Co‐development and evaluation of the Musculoskeletal Telehealth Toolkit for physiotherapists
Authors: Ezzat Allison M. , King Matthew G. , De Oliveira Silva Danilo , Pazzinatto Marcella F. , Caneiro J. P. , Gourd Stephanie , McGlasson Rhona , Malliaras Peter , Dennett Amy , Russell Trevor , Kemp Joanne L. , Barton Christian J. 
Published: December 2023

AbstractIntroductionIn‐person physiotherapy services are not readily available to all individuals with musculoskeletal conditions, especially those in rural regions or with time‐intensive responsibilities. The COVID‐19 pandemic highlighted that telehealth may facilitate access to, and continuity of care, yet many physiotherapists lack telehealth confidence and training. This project co‐developed and evaluated a web‐based professional development toolkit supporting physiotherapists to provide telehealth services for musculoskeletal conditions.MethodsA mixed‐methods exploratory sequential design applied modified experience‐based co‐design methods (physiotherapists [n = 13], clinic administrators [n = 2], and people with musculoskeletal conditions [n = 7]) to develop an evidence‐informed toolkit. Semi‐structured workshops were conducted, recorded, transcribed, and thematically analysed, refining the toolkit prototype. Subsequently, the toolkit was promoted via webinars and social media. The usability of the toolkit was examined with pre‐post surveys examining changes in confidence, knowledge, and perceived telehealth competence (19 statements modelled from the theoretical domains framework) between toolkit users (>30 min) and non‐users (0 min) using chi‐squared tests for independence. Website analytics were summarised.ResultsTwenty‐two participants engaged in co‐design workshops. Feedback led to the inclusion of more patient‐facing resources, increased assessment‐related visual content, streamlined toolkit organisation, and simplified, downloadable infographics. Three hundred and twenty‐nine physiotherapists from 21 countries completed the baseline survey, with 172 (52%) completing the 3‐month survey. Toolkit users had greater improvement in knowledge, confidence, and competence than non‐users in 42% of statements. Seventy‐two percentage of toolkit users said it changed their practice, and 95% would recommend the toolkit to colleagues. During the evaluation period, the toolkit received 5486 total views.DiscussionThe co‐designed web‐based Musculoskeletal Telehealth Toolkit is a professional development resource that may increase physiotherapist's confidence, knowledge, and competence in telehealth.
Topological Properties of a Non‐Hermitian Quasi‐1D Chain with a Flat Band
Authors: Martínez‐Strasser C. , Herrera M. A. J. , García‐Etxarri A. , Palumbo G. , Kunst F. K. , Bercioux D. 
Published: December 2023

AbstractThe spectral properties of a non‐Hermitian quasi‐1D lattice in two of the possible dimerization configurations are investigated. Specifically, it focuses on a non‐Hermitian diamond chain that presents a zero‐energy flat band. The flat band originates from wave interference and results in eigenstates with a finite contribution only on two sites of the unit cell. To achieve the non‐Hermitian characteristics, the system under study presents non‐reciprocal hopping terms in the chain. This leads to the accumulation of eigenstates on the boundary of the system, known as the non‐Hermitian skin effect. Despite this accumulation of eigenstates, for one of the two considered configurations, it is possible to characterize the presence of non‐trivial edge states at zero energy by a real‐space topological invariant known as the biorthogonal polarization. This work shows that this invariant, evaluated using the destructive interference method, characterizes the non‐trivial phase of the non‐Hermitian diamond chain. For the second non‐Hermitian configuration, there is a finite quantum metric associated with the flat band. Additionally, the system presents the skin effect despite the system having a purely real or imaginary spectrum. The two non‐Hermitian diamond chains can be mapped into two models of the Su‐Schrieffer‐Heeger chains, either non‐Hermitian, and Hermitian, both in the presence of a flat band. This mapping allows to draw valuable insights into the behavior and properties of these systems.
The progression and mechanisms of mental illness symptoms in university student‐athletes during the COVID‐19 pandemic
Authors: Labossière Sophie , Couture Sophie , Laurier Catherine , Lemieux Annie , Boudreault Véronique 
Published: December 2023

AbstractA few studies have examined mental illness symptoms in university student‐athletes during the COVID‐19 pandemic, but the limited use of longitudinal design limits the understanding of the progression of these symptoms and the mechanisms by which they developed. The present research aims to describe the trajectory of variation of mental illness symptoms (anxiety, depression, alcohol consumption disorders, and eating disorders) throughout the pandemic, to test causality between perceived stress and symptoms, and to identify individual characteristics (sociodemographic, perceived stress, and social support) influencing the trajectories of mental illness symptoms. On three occasions during the pandemic, 211 university student‐athletes were surveyed. Latent growth models and random intercept crossed‐lagged panel models were performed. Results indicate that anxiety and depressive symptoms significantly decreased throughout the COVID‐19 pandemic while alcohol consumption disorder symptoms significantly increased and eating disorder symptoms did not change significantly. Second, perceived stress was a significant cause of anxiety and depressive symptoms during this pandemic. Conversely, eating disorder symptoms significantly predicted perceived stress. Finally, average perceived stress and average social support availability throughout the COVID‐19 pandemic, and identifying as a visible minority, significantly predicted the trajectory of depressive symptoms, allowing for the identification of a sub‐population at higher risk. Based on these findings, teaching stress management strategies should be an essential component of programs to prevent mental illness symptoms in university student‐athletes. Reducing environmental stressors and their consequences among this population should also be prioritised.
An Ellagic Acid Coordinated Copper‐Based Nanoplatform for Efficiently Overcoming Cancer Chemoresistance by Cuproptosis and Synergistic Inhibition of Cancer Cell Stemness
Authors: Lu Shuaijun , Tian Hailong , Li Bowen , Li Lei , Jiang Hao , Gao Yajie , Zheng Lin , Huang Canhua , Zhou Yuping , Du Zhongyan , Xu Jia 
Published: December 2023

AbstractDrug resistance is one of the leading causes of treatment failure in current cancer chemotherapy. In addition to the classical drug efflux transporter‐mediated chemoresistance, cancer cells with stemness features play a crucial role in escaping the maximum impact of chemotherapy. To sensitize cancer chemotherapy, in a novel approach, the hedgehog pathway inhibitor ellagic acid (EA) is coordinated with Cu2+ to develop nanoscale metal–organic frameworks (EA‐Cu), which are then loaded with doxorubicin (DOX) and modified with targeted chondroitin sulfate (CS) to form the CS/E‐C@DOX nanoplatform (CS/NPs). Notably, EA inhibits stemness maintenance by suppressing the hedgehog pathway, while Cu2+ further decreases stemness features of tumor cells by disrupting mitochondrial metabolism, effectively enhancing DOX‐mediated chemotherapy. Meanwhile, EA can act synergistically with Cu2+ to cause mitochondrial dysfunction and cuproptosis, which effectively decreases ATP levels and subsequently suppresses the activity of P‐glycoprotein (P‐gp), thus reducing drug efflux and sensitizing DOX‐mediated chemotherapy. Additionally, the attached CS endows CS/NPs with specific tumor targeting properties, whereas EA‐Cu endows this nanoplatform with pH/glutathione (GSH) dual‐responsive release behavior. Taken together, CS/NPs exhibited excellent antitumor effects by inducing cuproptosis and significantly inhibiting cancer cell stemness, which has great potential for overcoming cancer chemoresistance.
Phylogenomics resolves the rediscovered Himalayan endemic Brachymeniopsis gymnostoma (Bryophyta, Funariaceae), as a species of Entosthodon, prompting also the transfer of Clavitheca poeltii
Authors: Zhang Li , Zuo Qin , Ma Wen‐Zhang , Shevock James R. , Patel Nikisha , Johnson Matthew , Medina Rafael , Wilding Nicholas , Goffinet Bernard 
Published: December 2023

AbstractTraits of the spore‐bearing generation have historically provided the basis for systematic concepts across the phylogenetic spectrum and depth of mosses. Whether taxa characterized by a simple sporophytic architecture are closely related or emerged from independent reduction is often ambiguous. Phylogenomic inferences in the Funariaceae, which hold the model taxon Physcomitrium patens, revealed that several such shifts in sporophyte complexity occurred, and mostly within the Entosthodon‐Physcomitrium complex. Here, we report the rediscovery of the monospecific, Himalayan endemic genera Brachymeniopsis and Clavitheca, after nearly 100 years and 40 years since their respective descriptions. The genera are characterized by, among other traits, their short sporophytes lacking the sporangial peristome teeth controlling spore dispersal. Phylogenomic inferences reveal that Brachymeniopsis gymnostoma arose within the clade of Entosthodon s.str., a genus with typically long‐exserted capsules. We therefore propose to transfer B. gymnostoma to the genus Entosthodon, as E. gymnostomus comb. nov. Furthermore, Clavitheca poeltii, the sole species of the genus, is morphologically highly similar to E. gymnostomus, and should also be transferred to Entosthodon, but is retained as a distinct taxon, E. poeltii comb. nov., until additional populations allow for testing the robustness of the observed divergence in costa and seta length between the Nepalese and Chinese populations.
Accuracy of MR neurography as a diagnostic tool in detecting injuries to the lingual and inferior alveolar nerve in patients with iatrogenic post-traumatic trigeminal neuropathy
Authors: Bangia Mado , Ahmadzai Iraj , Casselman Jan , Politis Constantinus , Jacobs Reinhilde , Van der Cruyssen Fréderic 
Published: December 2023

Abstract
Objectives
MR neurography has the ability to detect and depict peripheral nerve injuries. This study evaluated the potential of MR neurography in the diagnosis of post-traumatic trigeminal neuropathy.

Methods
Forty-one participants prospectively underwent MR neurography of the lingual and inferior alveolar nerves using a 3D TSE STIR black-blood sequence. Two blinded and independent observers recorded the following information for each nerve of interest: presence of injury, nerve thickness, nerve signal intensity, MR neurography Sunderland class, and signal gap. Afterwards, the apparent nerve-muscle contrast-to-noise ratio and apparent signal-to-noise ratio were calculated. Clinical data (neurosensory testing score and clinical Sunderland class) was extracted retrospectively from the medical records of patients diagnosed with post-traumatic trigeminal neuropathy.

Results
Compared to neurosensory testing, MR neurography had a sensitivity of 38.2% and specificity of 93.5% detecting nerve injuries. When differentiated according to clinical Sunderland class, sensitivity was 19.1% in the presence of a low class injury (I to III) and improved to 83.3% in the presence of a high class (IV to V). Specificity remained unchanged. The area under the curve using the apparent nerve-muscle contrast-to-noise ratio, apparent signal-to-noise ratio, and nerve thickness to predict the presence of an injury was 0.78 (p < .05). Signal intensities and nerve diameter increased in injured nerves (p < .05). Clinical and MR neurography Sunderland scores positively correlated (correlation coefficient = 0.53; p = .005).

Conclusions
This study shows that MR neurography can accurately differentiate between injured and healthy nerves, especially in the presence of a more severe nerve injury.

Clinical relevance statement
MR neurography is not only able to detect trigeminal nerve injuries, but it can also provide information about the anatomical specifications of the injury, which is not possible with clinical neurosensory testing. This makes MR neurography an added value in the management of post-traumatic trigeminal neuropathy.

Key Points
• The current diagnosis of post-traumatic trigeminal neuropathy is mainly based on clinical examination.
• MR neurography is able to visualize and stratify peripheral trigeminal nerve injuries.
• MR neurography contributes to the diagnostic process as well as to further decision-making.
Metabolically ‘extremely unhealthy’ obese and non-obese patients with diabetes and the risk of cardiovascular events: a French nationwide cohort study
Authors: Nabrdalik Katarzyna , Bisson Arnaud , Irlik Krzysztof , Fauchier Gregoire , Ducluzeau Pierre Henri , Lip Gregory Y. H. , Fauchier Laurent 
Published: December 2023

Abstract
Background
Non-obese patients with diabetes mellitus (DM) are becoming more prevalent, but their cardiovascular risk (CV) especially when accompanied with cardio-renal-metabolic co-morbidities (hypertension, chronic kidney disease, hyperlipidemia) is not well characterised. The aim of the study was to assess the CV risk among patients with DM in relation to obesity and cardio-renal-metabolic co-morbidities.

Materials and methods
This was a cohort study of all patients with DM without a history of major adverse cardiovascular event who were hospitalized for any reason in France in 2013 with at least 5 years of follow-up. They were categorized by the presence of obesity vs no obesity, as well as three cardio–renal–metabolic co-morbidities: hypertension, chronic kidney disease, hyperlipidemia. ‘Extremely unhealthy’ patients with DM were defined as those having all 3 co-morbidities.

Results
There were 196,112 patients (mean age 65.7 (SD 13.7) years; 54.3% males) included into the analysis. During a mean follow-up of 4.69 ± 1.79 years, when adjusted for multiple covariates, the non-obese and ‘extremely unhealthy’ obese patients had the highest risk of CV death [aHR 1.40 (95% CI, 1.22–1.61) and 1.48 (95% CI, 1.25–1.75), respectively]. The ‘extremely unhealthy’ obese had the highest risk of MACE-HF [aHR 1.84 (95% CI, 1.72–1.97)] and new-onset AF [aHR 1.64 (95% CI, 1.47–1.83)].

Conclusion
Both non-obese and obese patients with DM with associated cardio-renal-metabolic co-morbidities are an ‘extremely unhealthy’ phenotype with the highest risk of CV death and CV events.

Graphical abstract
Fentanyl Exposure and Detection Strategies Utilized by Clinical Trial Participants Seeking Linkage to Opioid Use Disorder Treatment at a Syringe Service Program
Authors: Watson Dennis P. , Ray Bradley , Phalen Peter , Duhart Clarke Sarah E. , Taylor Lisa , Swartz James , Gastala Nicole 
Published: December 2023

Abstract
Introduction
The USA continues to face a fentanyl-driven overdose epidemic. Prior research has demonstrated users of illicit opioids are concerned about fentanyl exposure and overdose, but the strategies they report using to detect fentanyl’s presence lack empirical support. This study compares self-report and biologically detected fentanyl use and investigates overdose risk and risk reduction behaviors among a sample of high-risk people who use opioids.

Methods
Structured enrollment interviews conducted as part of a larger clinical trial assessed self-reported fentanyl exposure as well as strategies used to determine believed fentanyl exposure and prevent overdose among 240 participants enrolled at a Chicago, IL syringe service program. Urinalysis measured actual fentanyl exposure.

Results
Most participants identified as African American (66.7%) and had considerable overdose experience (76.7% lifetime and 48% in the past year). Most also tested positive for fentanyl (93.75%) despite reporting no past year use of fentanyl or fentanyl-adulterated drugs (64.17%). The most utilized approaches reported for identifying fentanyl exposure were stronger effects of the drug (60.7%), sight or taste (46.9%), and being told by someone using the same drugs (34.2%). Few participants (14%) reported using fentanyl test strips. No significant associations were identified between self-report and urinalysis measures or urinalysis results and risk reduction strategies.

Conclusion
This study adds to prior fentanyl exposure risk research. The disconnect between participants’ fentanyl detection methods and reported overdose experiences supports the need for more research to identify and understand factors driving access and use of overdose prevention resources and strategies.
Molecular design of recyclable thermosetting polyimide and its composite with excellent mechanical and tribological properties
Authors: Wang Xiaoyue , Yang Zenghui , Wang Tingmei , Wang Qihua , Zhang Xinrui , Li Song 
Published: December 2023

AbstractRecyclability of thermosetting polymers and their composites is a challenge for alleviating environmental pollution and resource waste. In this study, solvent-recyclable thermosetting polyimide (PI) and its composite were successfully synthesized. The tensile strength, elongation at break, and Young’s modulus of PI are 108.70 ± 7.29 MPa, 19.35% ± 3.89%, and 2336.42 ± 128.00 MPa, respectively. The addition of reduced graphene oxide (RGO) not only enhances the mechanical properties of PI but also endows it with excellent tribological properties. The PI illustrates a high recycling efficiency of 94.15%, but the recycled composite exhibits inferior mechanical properties. The recycling and utilization of PI and its composite are realized through imine bonds (–C=N), which provides new guidance for solving the problem of environmental pollution and resource waste and is potential application in the field of sustainable tribology.
Is artificial intelligence and machine learning changing the ways of banking: a systematic literature review and meta analysis
Authors: Kalyani Sushil , Gupta Neha 
Published: December 2023

AbstractThis study aims to analyze the research work and present an SLR (Systematic Literature Review) on the initiatives taken by players in the banking sector, especially toward the technological innovations done in the field of AI (Artificial Intelligence) and ML (Machine Learning) that have contributed to the growth of the sector as well towards the ease of doing and building trust amongst consumers in the digitalized era of Banking. Growing security risks in cyberspace accompany the enormous and complex digital versions of virtual services. In total, 734 articles were reviewed to explore how Artificial Intelligence and Machine Learning have been used in various banking facets and how they have evolved to cater to different banking sector requirements. The findings reveal the areas where these modern-age technologies have been adopted and where the same can be used efficiently. Lastly, this study elaborates and evaluates the applications of these technologies on the parameters of scalability going further, keeping in mind the unprecedented dynamic times, and serving the very purpose of banks and how the banks are dealing with all the opportunities and challenges these new technologies bring in. This SLR also provides an overview of the research that can be taken up in future by the researchers in this domain.
Meeting families in various social situations: reflections from healthcare staff working with an extended home-visiting program in Sweden
Authors: Mangrio Elisabeth , Hjortsjö Maria 
Published: December 2023

Abstract
Objectives
Health inequalities exist among children in Sweden, and one effort that the Swedish government has focused on to promote health among small children and their parents is an extended home-visiting program during the child’s first 15 months. This study aimed to illuminate healthcare professionals’ experiences of meeting parents in different social situations during the home visits within Grow safely.

Methods
The chosen method was qualitative, and 13 interviews were carried out with healthcare, social, and dental professionals working with the extended home-visiting program within the child healthcare in the south of Sweden.

Results
The results revealed that the parents raised differing needs in the meetings with the healthcare professionals in the program. The needs included advice on children with special needs, support with problematic breastfeeding, and more psychosocial support. The professionals met different groups of parents, such as young parents or newly arrived migrant parents, that in different ways needed the team to reach out to them. The professionals also met families who came from better-off areas and who were not initially considered to really need the program. As the program progressed, these parents could see that diverse, unpredictable needs could be met by the intervention. For example, the program provided access to and advice from social workers, which in turn created contacts that lasted longer than the program itself.

Conclusions
The professionals encountered various family situations and needs within the extended home-visiting program. This highlights the need for a close collaboration between child healthcare nurses and social workers, in order to be able to support the families and work towards the aim of reaching equal health among all children in Sweden.
Multilevel meta-analysis of stated preference values of marine ecosystem services in China
Authors: Guo Jing , Chen Kai , Hynes Stephen 
Published: December 2023

AbstractOn the basis of a review of studies on the stated preference valuation of China’s marine ecosystem services conducted between 1996 and 2021, this paper presents a meta-analysis of the estimates of marine ecosystem service benefits by using a multilevel modeling approach. The results indicate that a range of factors influence the estimated economic values of China’s marine ecosystem services, including ecosystem area, ecosystem type, respondent identity, regional gross domestic product (GDP) per capita, ecosystem services being valued, valuation method, and hypothetical scenario being employed. Additionally, the meta-regression results indicate that the willingness to pay for marine ecosystem services in China depends largely on people’s perception of the importance of an ecosystem service. Such a perception is influenced by national policies, educational attainment, and the degree to which the service is linked to people’s lives. This situation is evidenced by the high willingness of people to pay for coastal wetlands and recreational services. People were also found to be most willing to pay for conservation scenarios and least willing to pay for environmental compensation scenarios. These findings contribute to the research on the valuation of marine ecosystem services in China and to the incorporation of research results into ecosystem-based management decisions by clarifying the effects of different factors on valuation estimates.
Positivity of repeat nasal MRSA PCR screening: a single-center experience
Authors: Earl Ali , Greenlee Sage , Fong Karen , Imlay Hannah , Spivak Emily S. 
Published: December 2023

Abstract
Repeating nasal methicillin-resistant Staphylococcus aureus (MRSA) polymerase chain reactions (PCRs) within 14 days may increase healthcare costs and inform anti-MRSA antibiotic therapy without known benefit. Within an inpatient admission, our retrospective, single-center evaluation found that conversion from negative to positive on repeat nasal MRSA PCR screen was uncommon (2%).