bluuebunny/crossref_metadata_2025_split huggingface dataset:
ANALISIS RELEVANSI NILAI-NILAI MORAL RITUAL SEKUJANG SUKU SERAWAI DALAM PEMBELAJARAN PPKN TEMATIK TERPADU SISWA KELAS V SDN 81 SELUMA
Authors: Darmansyah Ady , Puspa Djuwita  , Abdul Muktadir  
Published: November 2023

This study discusses the moral values of the Sekujang ritual of Serawai Tribe integrated in learning civic education for fifth grade elementary school students of 81 Seluma. The goal to be achieved is to describe the moral values in the Serawai tribe's Sekujang ritual which can be internalized in learning civic education for fifth grade students of the 81 Seluma elementary school. This research is a qualitative descriptive study with an ethnographic approach. The results showed that the class V teachers in the 81 Seluma elementary school could understand and interpret the ritual of the Sekujang tribe of Serawai, the thematic learning design of the civic education learning content on Theme 8 Sub-theme 2 Learning 3, internalization of Sekujang moral values in the civic education learning design for fifth grade students of 81 Seluma elementary school, and the Sekujang moral values evaluation design in the learning of civic education for fifth grade students of the 81 Seluma elementary school which was made by the teacher was not fully optimal. There has been an internalization of moral values in the design of civic education learning, but it has not been programmed and there is the relevance of the Sekujang ritual moral values in civic education learning. Keywords : Moral Values, Sekujang Rituals and Civic Education Learning
Dasar Kemampuan Mengajar: Analisis Deskriptif Pada Mahasiswa PGSD Sebagai Bahan Tindak Lanjut Perkuliahan
Authors: Wulandari Arina , Makhtuna Wulida , Mashud  
Published: November 2023

Penelitian ini bertujuan untuk menganalisis kemampuan dasar mengajar mahasiswa program studi Pendidikan Guru Sekolah Dasar sebagai bahan tindak lanjut perkuliahan pembelajaran PKn. Jenis penelitian adalah peneltian kuantitatif menggunakan metode survey. Subyek penelitian adalah mahasiswa Program Studi Pendidikan Sekolah Dasar yang memprogram matakuliah Pembelajaran PKn yang berjumlah 36 Mahasiswa. Intrumen penelitian menggunakan penilaian supervise guru yang terbagi pada; 1. aktivitas pendahuluan, 2. aktivitas inti pembelajaran, dan 3. aktivitas penutup pembelajaran, yang di dalamnya terdapat komponen kemampuan dasar mengajar, yaitu; 1) keterampilan membuka pelajaran, 2) keterampilan penguasaan materi, 3) interaksi proses pembelajaran, 4) penggunaan bahasa, 5) pengelolaan kelas, 6) evaluasi pembelajaran, 7) keterampilan menutup pembelajaran. Prosedur pengumpulan data penelitian meliputi; 1. mahasiswa menyusun rencana persiapan pembelajaran, 2. mahasiswa praktik micro teaching secara daring selama 20 menit, 3. dosen mengamati dan memberikan penilaian pembelajaran yang dilakukan oleh mahasiswa. Teknik analisis data penelitian menggunakan teknik deskriptif kuantitatif menerapkan analisis prosesntase. Hasil penelitian terbagi menjadi empat kategori yaitu; 1. kategori sangat baik terdapat pada komponen keterampilan penggunaan bahasa, 2. kategori baik terdapat pada komponen keterampilan membuka pelajaran, interaksi proses pembelajaran dan keterampilan menutup pembelajaran, 3) kategori cukup terdapat pada komponen pada komponen pengelolaan kelas, dan 4. kategori kurang terdapat pada komponen keterampilan penguasaan materi, dan evaluasi pembelajaran
Pengaruh Good Corporate Governance , Fee Audit Dan Spesialisasi Audit Terhadap Kualitas Audit Dengan Strategi Bisnis Klien Sebagai Variabel Moderasi
Authors: Nurhasanah Nurhasanah , Budiantoro Harry , Lapae Kanaya , Tantri Ningsih Hestin Agus , Faruqi Faris 
Published: November 2023

This study aims to examine the effect of Good Corporate Governance audit committee proxies, audit Fees and audit specialization on audit quality, as well as examine whether the client's business strategy can weaken the influence of audit committees, audit Fees and audit specialization on audit quality. This study used a sample of infrastructure sector companies listed on the Indonesia Stock Exchange (IDX) during the 2017-2021 period as many as 12 companies with a total sample of 60 financial reports based on a purposive sampling method with certain criteria. The analytical method used is multiple linear regression and Moderated Regression Analysis (MRA) with the SPSS Ver.26.0 application. The results showed that Good Corporate Governance , audit committee proxies and audit Fees had no effect on audit quality and audit specialization had a positive effect on audit quality. As well as business strategy is not able to weaken the influence of audit committees, audit Fees and audit specialization on audit quality.

Keywords: Good Corporate Governance (GCG), Audit Fee, Audit Specialization, Client Business Strategy and Audit Quality

Abstrak
Penelitian ini bertujuan untuk menguji pengaruh Good Corporate Governance proksi komite audit, Fee audit dan spesialisasi audit terhadap kualitas audit, serta menguji apakah strategi bisnis klien dapat memperlemah pengaruh komite audit, Fee audit dan spesialisasi audit terhadap kualitas audit. Penelitian ini menggunakan sampel perusahaan sektor infrastruktur yang terdaftar di Bursa Efek Indonesia (BEI) selama periode 2017-2021 sebanyak 12 perusahaan dengan total sampel 60 laporanʿkeuangan berdasarkan metode purposive sampling dengan kriteria tertentu. Metode analisis yang digunakan adalah regresi linier berganda dan Moderated Regression Analysis (MRA) dengan aplikasi SPSS Ver.26.0. Hasil penelitian menunjukan bahwa Good Corporate Governance proksi komite audit dan Fee audit tidak berpengaruh terhadap kualitas audit dan spesialisasi audit berpengaruh positif terhadap kualitas audit. Serta strategi bisnis tidak mampu memperlemah pengaruh komite audit, Fee audit dan spesialisasi audit terhadap kualitas audit.

Kata kunci: Good Corporate Governance (GCG), Fee Audit, Spesialisasi Audit, Strategi Bisnis Klien dan Kualitas Audit
THE ANTI-IMPERIAL GENRE PARADIGM OF THE CANADIAN POST-VICTORIAN NOVEL
Authors: Овчаренко Наталія 
Published: November 2023

The paper offers a comprehensive analysis of discursive anti-imperial models in Canadian post-Victorian novels. The set tasks relate to detailing the features of this genre paradigm. In particular, attention is focused on the study of its historical, literary, and cultural context. The explanation of the socio-historical background typical of classical English Victorianism, provided in the paper, helps to trace the evolution of the related genre on Canadian soil. Its reinterpretation was prompted by the polyethnic and cultural ‘mosaic’ of the country, which became a prerequisite for the emergence of original models in modern sociology, cultural studies, and fiction.
The study postulates the idea of an anti-imperial paradigm of the genre within the Dominion of Canada. Hence, the process of transforming the discourse of the Victorian novel into the post-Victorian one is demonstrated to be determined by the peculiarities of the post-colonial multicultural structure of the country, which manifests itself at the thematic, cognitive, psychological, and poetic levels. For the purpose of comprehensive analysis, the research is based on the plurality of historical and philosophical foundations within the field of ethics. The range of methods encompasses syncretic, cultural-historical, psychoanalytic, ‘close reading’, genetic, and gynocriticism.
The study led to the observation that the social pattern of the Victorian era (a strict religious and moral code, the pretext of which was Protestantism, mysticism, etc.) permeated Canadian prose as an echo of English Victorianism. There was an ontological dialogue between the Victorian era and post-Victorianism, between individuals and the times in which they lived. The relationship between literature and individuals of different cultural and historical periods had an evolutionary character. The evolution of the genre of the Canadian post-Victorian novel, particularly in the works by L. M. Montgomery, B. Moore, and M. Atwood, is related to the multifaceted style, which involves the use of diverse elements from various aesthetic forms. This synthesis is the result of an experiment with both new and traditional literary models in Canadian literature. The correlation between the classical and post-Victorian genres shows the functionality of such means as satire, pastiche, and simulacrum in the latter. These tools transform the Victorian novel into an ‘anti-Victorian’ one. The examination of the modern version of the classical genre demonstrates the heterogeneity of meanings, their layering and transmission, a new role and conceptual load, motivated by purely national means of explanation.
Over the course of an extended journey through time, the traditional Victorian models, adopted in the literature of the metropolis, had been transformed on Canadian soil. They acquired unique qualities, expanding the field of event and poetic content of the works by Canadian authors and demonstrating their solid post-Victorian anti-imperial discourse.
Aristotle on the Objects of Natural and Mathematical Sciences
Authors: Mendelsohn Joshua 
Published: November 2023

In a series of recent papers, Emily Katz has argued that on Aristotle's view mathematical sciences are in an important respect no different from most natural sciences: They study sensible substances, but not qua sensible. In this paper, I argue that this is only half the story. Mathematical sciences are distinctive for Aristotle in that they study things ‘from’, ‘through’ or ‘in’ abstraction, whereas natural sciences study things ‘like the snub’. What this means, I argue, is that natural sciences must study properties as they occur in the subjects from which they are originally abstracted, even where they reify these properties and treat them as subjects. The objects of mathematical sciences, on the other hand, can be studied as if they did not really occur in an underlying subject. This is because none of the properties of mathematical objects depend on their being in reality features of the subjects from which they are abstracted, such as bodies and inscriptions. Mathematical sciences are in this way able to study what are in reality non-substances as if they were substances.
Keterikatan kepada Tuhan dan Pertumbuhan iman terhadap Komitmen Organisasi pada jemaat Gereja di Surabaya
Authors: Lontoh Frederich Oscar , Chia Philip , Widianto Kasiatin , Prasetyo Widi , Triono Triono 
Published: November 2023

This research aims to determine whether there is an influence of attachement to to God and faith growth on Organizational Commitment among church congregations in Surabaya. The methodology used is quantitative with correlation analysis and multiple linear regression analysis. The population in this study consists of Christian church congregations in Surabaya, Indonesia, in accordance with predetermined respondent criteria. Respondents were selected through purposive random sampling. The instruments used in this research are the Closeness to God Scale, Faith Growth Scale, and Organizational Commitment Scale. Data analysis was conducted using partial correlation tests. The results of this study indicate a positive relationship between attachement to God, faith growth, and Organizational Commitment among Christian church congregations in the city of Surabaya, Indonesia. Partially and collectively, Organizational Commitment can be influenced by closeness to God and faith growth, even though the values are relatively low. In other words, these two independent variables are not the primary factors in the lives of Christian church congregations that can enhance their commitment to the local church.
ABSTRAK BAHASA INDOENSIA
Penelitian ini bertujuan untuk mengetahui apakah ada pengaruh Keterikatan kepada Tuhan dan Pertumbuhan iman terhadap Komitmen Organisasi pada jemaat Gereja di Surabaya. Metodologi yang digunakan adalah kuantitaif dengan analsis korelasi dan analisis regresi liner berganda. Populasi dalam penelitian ini adalah jemaat gereja-gereja Kristen di Surabaya, Indonesia, sesuai dengan kristeria responden yang telah ditentukan. Responden dipilih secara purposive random sampling. Instrumen yang digunakan dalam penelitian ini adalah Skala Kedekatan pada Tuhan, Pertumbuhan iman dan Skala Komitmen Organisasi. Analisis data menggunakan uji korelasi parsial. Hasil penelitian ini menunjukkan ada hubungan yang poisitif antara Keterikatan kepada Tuhan, Pertumbuhan iman dan Komitmen Organisasi pada jemaat gereja-gerja Kristen di kota Surabaya, Indonesia. Secara parsial dan secara bersama-sama Komitmen Organisasi dapat dipengaruhi oleh Kedekatan pada Tuhan dan Pertumbuhan iman sekalipun dengan nilai yang tergolong rendah. Dengan kata lain bahwa kedua variable independent tersebut adalah bukan faktor utama dalam kehidupan jemaat-jemaat Gereja Kristen yang dapat meningkatkan Komitmen Organisasi mereka kepada gereja lokal.
Causal effects of nonalcoholic fatty liver disease on cerebral cortical structure: a Mendelian randomization analysis
Authors: Mai Zhiliang , Mao Hua 
Published: November 2023

BackgroundPrevious studies have highlighted changes in the cerebral cortical structure and cognitive function among nonalcoholic fatty liver disease (NAFLD) patients. However, the impact of NAFLD on cerebral cortical structure and specific affected brain regions remains unclear. Therefore, we aimed to explore the potential causal relationship between NAFLD and cerebral cortical structure.MethodsWe conducted a Mendelian randomization (MR) study using genetic predictors of alanine aminotransferase (ALT), NAFLD, and percent liver fat (PLF) and combined them with genome-wide association study (GWAS) summary statistics from the ENIGMA Consortium. Several methods were used to assess the effect of NAFLD on full cortex and specific brain regions, along with sensitivity analyses.ResultsAt the global level, PLF nominally decreased SA of full cortex; at the functional level, ALT presented a nominal association with reduced SA of parahippocampal gyrus, TH of pars opercularis, TH of pars orbitalis, and TH of pericalcarine cortex. Besides, NAFLD presented a nominal association with reduced SA of parahippocampal gyrus, TH of pars opercularis, TH of pars triangularis and TH of pericalcarine cortex, but increased TH of entorhinal cortex, lateral orbitofrontal cortex and temporal pole. Furthermore, PLF presented a nominal association with reduced SA of parahippocampal gyrus, TH of pars opercularis, TH of cuneus and lingual gyrus, but increased TH of entorhinal cortex.ConclusionNAFLD is suggestively associated with atrophy in specific functional regions of the human brain.
Chromosome-level genome assembly of the largefin longbarbel catfish (Hemibagrus macropterus)
Authors: Ye Huan , Fan Jiahui , Hou Yanling , Yue Huamei , Ruan Rui , Li Shuang , Hu Chongjiang , Xie Yong , Li Chuangju 
Published: November 2023

The largefin longbarbel catfish, Hemibagrus macropterus, is an economically important fish species in southwestern China, with males growing faster than females. This study presents a high-quality chromosome-level genome assembly of the largefin longbarbel catfish, generated by integrating Illumina short reads, PacBio HiFi long reads, and Hi-C data. The assembled genome size was 858.5 Mb, with a contig and scaffold N50 of 5.8 Mb and 28.4 Mb, respectively. A total of 656 contigs were successfully anchored to 30 pseudochromosomes with a BUSCO score of 97.7%, consistent with the number of chromosomes analyzed by karyotype. The genome contained 29.5% repeat sequences, and a predicted total of 26,613 protein-coding genes, of which 25,769 (96.8%) were functionally annotated in different databases. Evolutionary analysis showed that H. macropterus was most closely related to H. wyckioides, with a divergence time of approximately 16.3 million years. Chromosomal syntenic relationships among H. macropterus, H. wyckioides, and Pelteobagrus fulvidraco revealed a one-to-one relationship for most chromosomes, except for break, fission, and inversion of some chromosomes. The first high-quality reference genome will not only provide a valuable genetic resource for the study of sex determination mechanisms and genetic breeding of largefin longbarbel catfish, but also contribute to comparative analyses of genome and chromosome evolution within Siluriformes.
The effect of anaerobic remineralization of the seagrass Halophila stipulacea on porewater biogeochemistry in the Gulf of Aqaba
Authors: Soto Neta , Winters Gidon , Antler Gilad 
Published: November 2023

IntroductionSeagrasses form oxidizing microenvironments around their roots, creating complex and strong redox gradients, thus affecting the rates of microbial carbon mineralization in their surrounding sediments. Since seagrasses are continuously being lost worldwide, a deeper understanding of the changes that occur within different seagrass sediments following the disappearance of the plants is of ecological and global importance.MethodsWe conducted a slurry experiment with sediments that have different characteristics from the northern tip of Gulf of Aqaba; the different sediments included different compartments of the tropical seagrass Halophila stipulacea (old and young leaves, rhizomes, or roots). We measured the changes over time in dissolved inorganic carbon (DIC), alkalinity, ferrous iron (Fe2+), hydrogen sulfide (H2S), sulfate (SO42-), and sulphur isotope ratios in sulfate within water. These measurements were used to calculate the rate of remineralization of each seagrass compartment, allowing us to predict the potential effects of the disappearance of different H. stipulacea compartments on key microbial processes in the surrounding environment.ResultsWe show that H. stipulacea’s rhizomes had the fastest decomposition rates, followed by the young leaves, roots, and old leaves (which also indicates the preservation potential of old leaves).DiscussionHigh concentrations of hydrogen sulfide were detected only in the slurries containing rhizomes and young leaves. High sulfide concentrations can lead to seagrass mortality and cause a positive feedback loop where the loss of seagrass due to sulfide generates further sulfide accumulation. This positive feedback loop can also be further reinforced by the loss of burrowing fauna in the sediment. This emphasizes the importance of understanding the extent of different pathways of seagrass disappearance on the surrounding environment and other geochemical feedbacks.
Low geriatric nutritional risk index as a poor prognostic biomarker for immune checkpoint inhibitor treatment in solid cancer
Authors: Zhang Lilong , Wang Kunpeng , Kuang Tianrui , Deng Wenhong , Hu Peng , Wang Weixing 
Published: November 2023

ObjectiveIn this investigation, we focused on the geriatric nutritional risk index (GNRI), a comprehensive metric that takes into account the patient’s ideal weight, actual weight, and serum albumin levels to measure malnutrition. Our primary objective was to examine the predictive value of GNRI-defined malnutrition in determining the response to immunotherapy among cancer patients.MethodsRelevant articles for this study were systematically searched in PubMed, the Cochrane Library, EMBASE, and Google Scholar up to July 2023. Our analysis evaluated overall survival (OS), progression-free survival (PFS), objective response rate (ORR), and disease control rate (DCR) as clinical outcomes.ResultsThis analysis comprised a total of eleven articles encompassing 1,417 patients. The pooled results revealed that cancer patients with low GNRI levels exhibited shorter OS (HR: 2.64, 95% CI: 2.08–3.36, p &lt; 0.001) and PFS (HR: 1.87, 95% CI: 1.46–2.41, p &lt; 0.001), and lower ORR (OR: 0.46, 95% CI: 0.33–0.65, p &lt; 0.001) and DCR (OR: 0.42, 95% CI: 0.29–0.61, p &lt; 0.001). Sensitivity analyses confirmed that the above results were stable. Egger’s and Begg’s tests revealed that there was no publication bias in the above results.ConclusionOur results imply that the GNRI is a useful predictor of immunotherapy response in cancer patients.
Overnight staffing in Canadian neonatal and pediatric intensive care units
Authors: Maratta Christina , Hutchison Kristen , Nicoll Jessica , Bagshaw Sean M. , Granton John , Kirpalani Haresh , Stelfox Henry Thomas , Ferguson Niall , Cook Deborah , Parshuram Christopher S. , Moore Gregory P. 
Published: November 2023

AimInfants and children who require specialized medical attention are admitted to neonatal and pediatric intensive care units (ICUs) for continuous and closely supervised care. Overnight in-house physician coverage is frequently considered the ideal staffing model. It remains unclear how often this is achieved in both pediatric and neonatal ICUs in Canada. The aim of this study is to describe overnight in-house physician staffing in Canadian pediatric and level-3 neonatal ICUs (NICUs) in the pre-COVID-19 era.MethodsA national cross-sectional survey was conducted in 34 NICUs and 19 pediatric ICUs (PICUs). ICU directors or their delegates completed a 29-question survey describing overnight staffing by resident physicians, fellow physicians, nurse practitioners, and attending physicians. A comparative analysis was conducted between ICUs with and without in-house physicians.ResultsWe obtained responses from all 34 NICUs and 19 PICUs included in this study. A total of 44 ICUs (83%) with in-house overnight physician coverage provided advanced technologies, such as extracorporeal life support, and included all ICUs that catered to patients with cardiac, transplant, or trauma conditions. Residents provided the majority of overnight coverage, followed by the Critical Care Medicine fellows. An attending physician was in-house overnight in eight (15%) out of the 53 ICUs, seven of which were NICUs. Residents participating in rotations in the ICU would often have rotation durations of less than 6 weeks and were often responsible for providing care during shifts lasting 20–24 h.ConclusionMost PICUs and level-3 NICUs in Canada have a dedicated in-house physician overnight. These physicians are mainly residents or fellows, but a notable variation exists in this arrangement. The potential effects on patient outcomes, resident learning, and physician satisfaction remain unclear and warrant further investigation.
Safety, tolerability, and pharmacokinetics of TG-1000, a new molecular entity against influenza virus: first-in-human study
Authors: Xu Su-Mei , Chang Li-Wen , Tsai Cheng-Yuan , Liu Wan-Li , Li Dai , Li Shan-Shan , Li Xiao-Min , Xu Ping-Sheng 
Published: November 2023

Background: The cap-snatching mechanism of influenza virus mRNA transcription is strongly suppressed by TG-1000, a prodrug rapidly metabolized into TG-0527, is a potent cap-dependent nucleic acid endonuclease inhibitor. Herein, we aimed to assess the safety, tolerability, and pharmacokinetics of TG-1000 in healthy participants and the effect of food on the pharmacokinetics and safety of TG-1000.Method: The study was divided into 2 parts: Part A [Single Ascending-Dose (SAD) study, 10–160 mg] and Part B [Food-Effect (FE) study, 40 mg] were launched sequentially. The study included 66 participants for both investigations. We administered different TG-1000 capsules or placebo doses per the study protocol and collected blood samples for pharmacokinetic assessments at specific times. In plasma, TG-1000 and its active metabolite TG-0527 were assayed, and PK parameters were determined.Results: In SAD, the increase in AUC was less than the proportional increase in dose over the 20–160 mg dose range, while the increase in Cmax was proportional to the increase in dose. In the 10–160 mg dose range, T1/2, λz and Tmax of TG-0527 were dose-independent; and T1/2 and Tmax were within 33.8–39.4 h and 3.02–6 h, respectively. In FE, the AUC0-inf, AUC0-last, and Cmax of TG-0527 decreased by approximately 17.52%, 18.76%, and 41.35%, respectively, and the Tmax delay was around 1.50 h. No serious adverse events occurred during the studies.Conclusion: Overall, TG-1000 was well tolerated and exhibited an acceptable safety and PK profile, supporting further clinical investigation of TG-1000 for the treatment of influenza.