bluuebunny/crossref_metadata_2025_split huggingface dataset:
Study of wear and corrosion resistance of ATO nanoparticle–doped micro‐arc oxide film layers
Authors: Chen XiaoWen , Song Hao , Pu Huan , Zheng Rui , Zhang Meng , Zhang DeFen 
Published: November 2023

AbstractIn order to enhance the corrosion and wear resistance of aluminum alloys in complex and variable environments, an Al2O3 ceramic film was prepared on the surface of 7A04 aluminum alloy in a silicate electrolyte system using a micro‐arc oxidation technique. Subsequently, antimony tin oxide (ATO) nanoparticles were used to dope the micro‐arc oxidation film to enhance the protective properties of the 7A04 aluminum alloy. The structural characteristics of the film were investigated by examining the surface and cross‐sectional morphology and the composition of the physical phases. The results show that ATO nanoparticles can promote the micro‐arc oxidation reaction, improve the surface morphology of the film layer, increase the thickness of the film layer and the denseness after sintering, and enter the film layer in the form of melt wrapping, which plays a role in refining the grain. In the study of the wear resistance and corrosion resistance of ATO‐doped ceramic film layers, it was found that the introduction of ATO nanoparticles did not significantly improve the wear resistance of the micro‐arc oxide ceramic film layers but significantly improved the corrosion resistance of the film layers.
Suicide in the 1970s: A Second Look
Authors: Comstock Betsy S. 
Published: November 2023

ABSTRACT: The decade of the 70's has been reviewed with the document Suicide Prevention in the 70's serving as a guide. Twenty‐one goals put forward in the report were reviewed in light of subsequent progress in the field. Although progress was noted on many fronts, four areas were outstanding in the sense that envisioned goals were met or exceeded. These involved the areas of promulgation of information about suicide, establishment of standards and certification procedures, development of regional organizations to forward training and program development, and education of the public to improve awareness of suicide as a public problem. This analysis also identified areas where little or no progress has been made. From this there developed four recommendations:

The funding and establishment of a national case file using a standard nomenclature and a standard data base to improve epidemiologic knowledge, and to provide pooled data appropriate for more sophisticated research analyses.
The establishment of a task force to study the application of program evaluation methods to suicide prevention efforts.
The development of new programs at local levels to try to reach known high‐risk groups and to provide relevant programs of suicide prevention for them.
Making creative efforts toward elaboration of a comprehensive theory of life‐threatening behavior and exploration of developmental correlates of such behavior.
Global and domain‐specific self‐esteem from middle childhood to early adolescence: Co‐developmental trajectories and directional relations
Authors: Gong Xue , Zheng Jiamin , Zhou Jianhua , Huebner E. Scott , Tian Lili 
Published: November 2023

AbstractObjectiveThe study used both person‐centered (i.e., parallel process latent class growth modeling) and variable‐centered (i.e., random intercept cross‐lagged panel modeling) approaches to examine developmental changes in global and domain‐specific self‐esteem from middle childhood to early adolescence.MethodA total of 715 Chinese youth participated (54.3% boys; 45.7% girls; Mage = 9.96; SD = 0.51) in a 6‐wave longitudinal study with 6‐month intervals.ResultsParallel process latent class growth modeling identified three co‐developmental trajectories of global and domain‐specific self‐esteem: Congruent high increasing and then flattening global and domain‐specific self‐esteem, congruent moderate domain‐specific self‐esteem with convex global self‐esteem, and congruent low with concave appearance and global self‐esteem. Results from random intercept cross‐lagged panel modeling found reciprocal within‐person associations between academic self‐esteem and global self‐esteem; global self‐esteem significantly predicted social self‐esteem, while physical appearance self‐esteem significantly predicted global self‐esteem.ConclusionEvidence was provided for top‐down and bottom‐up effects of self‐esteem among Chinese youth. The findings provided new insight into the development of self‐esteem in youth.
Correlation of opioid antinociception and hypothermia in dogs—An animal welfare refinement
Authors: KuKanich Butch , KuKanich Kate , Tzic Astrid D. Carcamo , Anderson Elayna E. 
Published: November 2023

AbstractThe purpose of this study was to assess antinociception and correlation of antinociception and hypothermic effects after intravenous opioids in dogs. Nine healthy male Beagles were enrolled in the study. They were acclimated to a thermal nociceptive device, then received three IV treatments (saline, butorphanol 0.4 mg/kg and methadone 0.5 mg/kg) in a randomized complete block design. Rectal temperature and thermal withdrawals were assessed prior to and 0.5–6 h after drug administration. One dog was excluded due to lack of withdrawal to thermal stimuli. Rectal temperatures were not significantly different between treatments at time 0, but significantly decreased from 0.5 to 5 h for both opioids compared to saline. Withdrawals were significantly decreased, compared to saline, from 0.5 to 4 h for butorphanol and 0.5–5 h for methadone. A significant (p = .0005) and moderate (R2 = .43) correlation between antinociception and hypothermia occurred. Based on these data, intravenous butorphanol (0.4 mg/kg) and methadone (0.5 mg/kg) provided 4 and 5 h of antinociception, respectively. Opioid hypothermia can serve as an easy, noninvasive and humane manner for preclinical assessment of opioid antinociception in dogs prior to evaluation in clinical trials. This is a major refinement in animal welfare for assessing novel opioids, opioid doses and dose intervals in dogs.
Deep learning‐based automatic classification of three‐level surface information in bridge inspection
Authors: Zhang He , Shen Zhijing , Lin Zhenhang , Quan Liwei , Sun Liangfeng 
Published: November 2023

AbstractBridge inspection ensures that in‐service bridges are managed and maintained in conformity. To enhance the accuracy and efficiency of bridge inspection, an automatic hierarchical model is proposed, which enables the classification and correlation of bridge surface images at three levels, namely, at the structure, component, and defect type level. Thus, the impact of both the defect types and the affected components on bridge safety can be simultaneously considered. The proposed model uses a group of sub‐models instead of the common flat network to realize the multiple tasks, which is advantageous in accuracy, training simplicity, and scalability. The classification accuracy of the hierarchical model in three levels has reached 96%, 92%, and 81%. Results demonstrate the effectiveness of the proposed method in the classification of multi‐scale targets. This study may provide a new strategy for developing a systematic and easily adaptable detection framework for practical bridge engineering.
The phosphodiesterase DibA interacts with the c‐di‐GMP receptor LapD and specifically regulates biofilm in Pseudomonas putida
Authors: Nie Hailing , Nie Liang , Xiao Yujie , Song Miaomiao , Zhou Tiantian , He Jinzhi , Chen Wenli , Huang Qiaoyun 
Published: November 2023

AbstractThe ubiquitous bacterial second messenger c‐di‐GMP is synthesized by diguanylate cyclase and degraded by c‐di‐GMP‐specific phosphodiesterase. The genome of Pseudomonas putida contains dozens of genes encoding diguanylate cyclase/phosphodiesterase, but the phenotypical–genotypical correlation and functional mechanism of these genes are largely unknown. Herein, we characterize the function and mechanism of a P. putida phosphodiesterase named DibA. DibA consists of a PAS domain, a GGDEF domain, and an EAL domain. The EAL domain is active and confers DibA phosphodiesterase activity. The GGDEF domain is inactive, but it promotes the phosphodiesterase activity of the EAL domain via binding GTP. Regarding phenotypic regulation, DibA modulates the cell surface adhesin LapA level in a c‐di‐GMP receptor LapD‐dependent manner, thereby inhibiting biofilm formation. Moreover, DibA interacts and colocalizes with LapD in the cell membrane, and the interaction between DibA and LapD promotes the PDE activity of DibA. Besides, except for interacting with DibA and LapD itself, LapD is found to interact with 11 different potential diguanylate cyclases/phosphodiesterases in P. putida, including the conserved phosphodiesterase BifA. Overall, our findings demonstrate the functional mechanism by which DibA regulates biofilm formation and expand the understanding of the LapD‐mediated c‐di‐GMP signaling network in P. putida.
Public management frontiers in guaranteed income programs: Advancing implementation
Authors: Berman Evan , Gonzalez Lauro , Diniz Eduardo H. , Alves Mário Aquino 
Published: November 2023

AbstractThis viewpoint analyzes recent experiments in guaranteed income (GI) projects and identifies implementation issues that extend the frontiers of public administration. GI programs provide low‐income individuals with substantial and regular cash with few or no strings or conditions attached and are being used to assist the lower income population, including informal workers who are left out of many government programs. The following implementation issues are discussed as frontiers in current public administration research and theory: (1) increasing the federal role in vertical collaboration; (2) improving data integration across levels of government; and (3) finding new solutions to financial and political sustainability. As GI programs and experiments proliferate, it becomes critical to examine implementation and not just outcomes or impact.
Guarding skin under PPE: Mechanistic insights and technological innovations
Authors: Lu Junru , Jiang Guan 
Published: November 2023

AbstractIn the presence of diseases transmitted through respiratory droplets and direct contact, healthcare workers (HCWs) necessitate the use of personal protective equipment (PPE). For optimal safety, PPE should securely conform to the skin during extended wear. However, conventional PPE often lacks adequate air permeability and hygroscopicity, trapping heat and moisture emitted by the body within the enclosure. Such a hot and humid internal environment can induce skin damage, such as erythema, rash, pruritus, and itching among others, leading to microbial growth on the skin surface, the production of inflammatory mediators at the wound site and an increased risk of infection. This review strives to comprehensively elucidate the fundamental mechanisms triggering adverse skin reactions and their resultant manifestations. Furthermore, we explore recent advancements aimed at inhibiting these mechanisms to effectively mitigate the occurrence of skin lesions.
Mechanical properties of unbound limestone aggregates replaced by recycled glass aggregate for pavement in Canada/Quebec
Authors: Amlashi Sahar Mohsenian Hadad , Vaillancourt Michel , Carter Alan , Bilodeau Jean-Pascal , Khaksar Najafi Elmira , Rahbar-Rastegar Reyhaneh 
Published: November 2023

This study investigated the use of recycled glass aggregate (RG) as unbound base/subbase material. The experimental tests included compaction, Los Angeles, Micro-Deval, and California bearing ratio (CBR) tests. In this regard, a fine proportion of course limestone aggregate (MG20) was replaced by RG with size ranging from 0 to 5 mm based on the volumetric method. Adding RG to the coarse aggregate improved durability in wet conditions, which is more representative of the field condition of Canada/Quebec, but decreased in dry conditions. CBR values decreased with increasing RG inclusion, but all blends with 0%–100% RG in the fine fraction of MG20 met minimum requirements for unbound granular layers in Quebec. A simple model predicting the resilient modulus values of these materials based on CBR values at different stress levels was suggested. This equation estimates Mr values of various aggregate-RG blends under a wide range of mean stresses based on their CBR values.
Thermal neutron detection by means of Timepix3
Authors: Tamburrino A. , Claps G. , Contessa G. M. , Pietropaolo A. , Cordella F. , De Leo V. , Montereali R. M. , Vincenti M. A. , Nigro V. , Gatto R. , Pacella D. 
Published: November 2023

AbstractThermal neutron detection plays a crucial role in numerous scientific and technical applications such as nuclear reactor physics, particle accelerators, radiotherapy, materials analysis and space exploration. There are several challenges associated with the accurate identification and quantification of thermal neutrons. The present work proposes a detailed characterization of a Timepix3 (TPX3) detector equipped with a Lithium Fluoride ($$^6$$

6

LiF) converter in order to study its response to thermal neutrons that are identified through the $$^6$$

6

Li(n,$$\alpha$$
α
)$$^3$$

3

H reaction. The TPX3-based test system has been installed at the HOTNES facility in ENEA and the analysis highlighted its excellent performance showing high effectiveness in the identification of neutrons through morphological analysis of tracks produced by alpha and triton particles, after accurate discrimination from the gamma background. With the use of Monte Carlo simulations, it has been demonstrated that the main contribution is due to tritons and its signal can be used effectively in the identification of thermal neutrons obtaining an efficiency of 0.9 % for 25 meV neutrons. This allows the TPX3 to have important applications as an environmental monitor for thermal neutrons. This monitoring system can be simply realized and is easy to manage because of its compact size and its digital acquisition that allows a real-time analysis.
Transcatheter Palliation With Pulmonary Artery Flow Restrictors in Neonates With Congenital Heart Disease: Feasibility, Outcomes, and Comparison With a Historical Hybrid Stage 1 Cohort
Authors: Sperotto Francesca , Lang Nora , Nathan Meena , Kaza Aditya , Hoganson David M. , Valencia Eleonore , Odegard Kirsten , Allan Catherine K. , da Cruz Eduardo M. , Del Nido Pedro J. , Emani Sitaram M. , Baird Christopher , Maschietto Nicola 
Published: November 2023

BACKGROUND:
Neonates with complex congenital heart disease and pulmonary overcirculation have been historically treated surgically. However, subcohorts may benefit from less invasive procedures. Data on transcatheter palliation are limited.

METHODS:
We present our experience with pulmonary flow restrictors (PFRs) for palliation of neonates with congenital heart disease, including procedural feasibility, technical details, and outcomes. We then compared our subcohort of high-risk single ventricle neonates palliated with PFRs with a similar historical cohort who underwent a hybrid Stage 1. Cox regression was used to evaluate the association between palliation strategy and 6-month mortality.

RESULTS:
From 2021 to 2023, 17 patients (median age, 4 days; interquartile range [IQR], 2–8; median weight, 2.5 kilograms [IQR, 2.1–3.3]) underwent a PFR procedure; 15 (88%) had single ventricle physiology; 15 (88%) were high-risk surgical candidates. All procedures were technically successful. At a median follow-up of 6.2 months (IQR, 4.0–10.8), 13 patients (76%) were successfully bridged to surgery (median time since PFR procedure, 2.6 months [IQR, 1.1–4.4]; median weight, 4.9 kilograms [IQR, 3.4–5.8]). Pulmonary arteries grew adequately for age, and devices were easily removed without complications. The all-cause mortality rate before target surgery was 24% (n=4). Compared with the historical hybrid stage 1 cohort (n=23), after adjustment for main confounding (age, weight, intact/severely restrictive atrial septum or left ventricle to coronary fistulae), the PFR procedure was associated with a significantly lower all-cause 6-month mortality risk (adjusted hazard ratio, 0.26 [95% CI, 0.08–0.82]).

CONCLUSIONS:
Transcatheter palliation with PFR is feasible, safe, and represents an effective strategy for bridging high-risk neonates with congenital heart disease to surgical palliation, complete repair, or transplant while allowing for clinical stabilization and somatic growth.
Patterns of Aortic Dilation in Tetralogy of Fallot: An Analysis of 100 Fetal Echocardiograms Compared With Matched Controls
Authors: Dasgupta Minnie N. , Kaplinski Michelle A. , Reddy Charitha D. , Collins R. Thomas 
Published: November 2023

Background
Although aortic dilation is common in tetralogy of Fallot (TOF), its progression and risk of dissection are not well understood. The mechanism of dilation is primarily attributed to increased flow in utero; an alternative is unequal septation of the truncus arteriosus resulting in a larger aorta and inherently hypoplastic pulmonary artery (PA). If the latter is true, we hypothesize the aorta to PA ratio in TOF is stable throughout gestation, and sums of great artery dimensions are similar to controls.

Methods and Results

We performed a single‐center retrospective study of fetuses with TOF (2014–2020) and matched controls. We compared sums of diameters, circumferences, and cross‐sectional areas of the aorta and PA and evaluated the aorta to PA ratio across gestation in 2 TOF subtypes: pulmonary stenosis and atresia (TOF‐PA). There were 100 echocardiograms with TOF (36% TOF‐PA) with median gestational age of 31 weeks (interquartile range 26.5–34.4) and median maternal age of 34 years (interquartile range 30–37). There were no differences in sums of great artery dimensions between TOF‐pulmonary stenosis and controls. In TOF‐PA, sums were significantly lower than controls (
P
values <0.01). The aorta to PA ratio was stable throughout gestation (Pearson's
r
=0.08 [95% CI, −0.12 to 0.27], −0.06 [95% CI, −0.25 to 0.14]).

Conclusions
The aorta in fetal TOF is large but grows proportionally throughout gestation, with sums of great artery dimensions similar to controls. TOF‐PA appears distinct from TOF‐pulmonary stenosis (with smaller sums), warranting further investigation. In conclusion, our findings suggest an intrinsic developmental mechanism contributes to aortic dilation in TOF.
Serum neurofilament light chain levels in migraine patients: a monocentric case–control study in China
Authors: Fang Jie , Wu Jielong , Zhang Tengkun , Yuan Xiaodong , Zhao Jiedong , Zheng Liangcheng , Hong Ganji , Yu Lu , Lin Qing , An Xingkai , Jing Chuya , Zhang Qiuhong , Wang Chen , Wang Zhanxiang , Ma Qilin 
Published: November 2023

Abstract
Purpose
Serum neurofilament light chain (sNfL) can reflect nerve damage. Whether migraine can cause neurological damage remain unclear. This study assesses sNfL levels in migraine patients and explores whether there is nerve damage in migraine.

Methods
A case–control study was conducted in Xiamen, China. A total of 138 migraine patients and 70 healthy controls were recruited. sNfL (pg/mL) was measured on the single-molecule array platform. Univariate, Pearson correlation and linear regression analysis were used to assess the relationship between migraine and sNfL levels, with further subgroup analysis by migraine characteristics.

Results
Overall, 85.10% of the 208 subjects were female, with a median age of 36 years. sNfL levels were higher in the migraine group than in the control group (4.85 (3.49, 6.62) vs. 4.11 (3.22, 5.59)), but the difference was not significant (P = 0.133). The two groups showed an almost consistent trend in which sNfL levels increased significantly with age. Subgroup analysis showed a significant increase in sNfL levels in patients with a migraine course ≥ 10 years (β = 0.693 (0.168, 1.220), P = 0.010). Regression analysis results show that age and migraine course are independent risk factors for elevated sNfL levels, and there is an interaction between the two factors. Patients aged < 45 years and with a migraine course ≥ 10 years have significantly increased sNfL levels.

Conclusions
This is the first study to evaluate sNfL levels in migraine patients. The sNfL levels significantly increased in patients with a migraine course ≥ 10 years. More attention to nerve damage in young patients with a long course of migraine is required.
The HEARTS ECG workshop: a novel approach to resident and student ECG education
Authors: El-Baba Mazen , McLaren Jesse , Argintaru Niran 
Published: November 2023

Abstract
Objectives
ECG interpretation is a life-saving skill in emergency medicine (EM), and a core competency in undergraduate medical curricula; however, confidence for residents/students is low. We developed a novel educational intervention—the HEARTS ECG workshop—that provides a systematic approach to ECG interpretation, teaches EM residents through the process of teaching medical students and highlights emergency management.

Methods
We used the Kern Approach to Curriculum Development. A review of ECG education literature and a targeted needs assessment of local students/residents led to goals and objectives including systematic ECG interpretation with clinical relevance. ECGs were selected based on a national consensus of EM program directors and categorized into 5 common emergency presentations. The educational strategy included content based on HEARTS approach (Heart rate/rhythm, Electrical conduction, Axis, R-wave progression, Tall/small voltages, and ST/T changes), and methods including flipped classroom and near-peer teaching. Evaluation and feedback were based on the Kirkpatrick program evaluation. The workshop was piloted with 6 junior EM residents and 58 medical students, and repeated with nine residents and 68 students from four medical schools.

Results
Residents and students agreed or strongly agreed that the workshop improved their perceived ability (100% and 95%, respectively) and confidence (77% and 88%, respectively) in interpreting ECGs. Reports of ECG interpretation causing anxiety declined from pre-workshop (61% and 83% respectively) to post-workshop (38% and 37% respectively). Residents reported behavior change: 3 months after the workshop, 92.3% reported ongoing use of the HEARTS approach clinically and through teaching medical students on shifts. Reported workshop strengths included the pre-workshop material, the clinical application, facilitator-to-learner ratio, interactivity, the ease of remembering and applying the HEARTS mnemonic, and the iterative application of the approach. Suggested changes included longitudinal sessions with graded difficulty, and allocating more time for introductory material for ease of understanding.

Conclusion
The HEARTS ECG workshop is an innovative pedagogical method that can be adapted for all levels of training. Future directions include integration in undergraduate medical and EM residency curricula, and workshops for physicians to update ECG interpretation skills.