bluuebunny/crossref_metadata_2025_split huggingface dataset:
Autophagy Activity in Epicardial Cells in Acute Pericarditis
Authors: Dergilev K. V. , Tsokolaeva Z. I. , Gureenkov A. D. , Rasulova M. T. , Parfenova E. V. 
Published: December 2023

Pericarditis is a group of polyetiological diseases often associated with emergence of life–threatening conditions. Poor knowledge of underlying cellular mechanisms and lack of relevant approaches to investigation of pericarditis result in major challenges in diagnosis and treatment.The aim of this work was to identify changes in the activity of autophagy in epicardial cells in acute pericarditis.Materials and methods. Acute pericarditis in mice was induced by intrapericardial injection of Freund's adjuvant in the study group (n=15). The control group included animals receiving either intrapericardial injection of phosphate-buffered saline (PBS) (n=15), or sham surgery without injections (n=7). On Days 3 or 5 after surgery the animals were euthanized under isoflurane anesthesia. Immunofluorescence staining of cardiac tissue cryo-sections and immunoblotting were used to assess the intensity of inflammation and autophagy in the epicardium.Results. Inflammation and other signs of acute pericarditis resulting in thickening of some epicardial areas were found: 68+9% in the control (after PBS injection) and 124+22% after Freund's adjuvant injection (p=0.009); other signs included cellular infiltration of epicardium and multiple adhesions. The epicardial layer exhibited signs of mesothelial cells reorganization with 11-fold increase of autophagy markers LC3 II/LC3 I ratio: 0.07+0.02 in the control group (after PBS injection) and 0.84+0.07 - in acute pericarditis (p=0.04), and accumulation of collagen fibers.Conclusion. Development of acute pericarditis is accompanied by activation of epicardial mesothelial cells, intensified autophagy and development of fibrous changes in epicacardial/ subepicardial areas.
Prompting Metalinguistic Awareness in Large Language Models: ChatGPT and Bias Effects on the Grammar of Italian and Italian Varieties
Authors: Massaro Angelapia , Samo Giuseppe 
Published: December 2023

We explore ChatGPT’s handling of left-peripheral phenomena in Italian and Italian varieties through prompt engineering to investigate 1) forms of syntactic bias in the model, 2) the model’s metalinguistic awareness in relation to reorderings of canonical clauses (e.g., Topics) and certain grammatical categories (object clitics). A further question concerns the content of the model’s sources of training data: how are minor languages included in the model’s training? The results of our investigation show that 1) the model seems to be biased against reorderings, labelling them as archaic even though it is not the case; 2) the model seems to have difficulties with coindexed elements such as clitics and their anaphoric status, labeling them as ‘not referring to any element in the phrase’, and 3) major languages still seem to be dominant, overshadowing the positive effects of including minor languages in the model’s training.
Dieulafoy's lesion, the endovascular approach as a therapeutic option when endoscopic treatment has failed: A case report and brief review
Authors: Hayashi-Mercado César , González-Urueta Miguel Uriel , Aguilar-West Abelardo Alexanders , Montiel-Moreno María Dolores 
Published: December 2023

AbstractDieulafoy's lesion is defined as a dilated submucosal artery that can cause spontaneous rupture and massive gastrointestinal bleeding. It is usually an incidental finding and is identified as a prominent linear or serpentine artery.We report the case of a 47-year-old patient who presented with a Dieulafoy's lesion located in the gastric fundus, which was repeatedly treated with clipping and endoscopic sclerosis, without resolving. She presented to the interventional radiology service for endovascular treatment, which after performing angiography confirmed active bleeding at the level of the left gastric artery and proceeded to embolize with 2 coils. This is a case where endovascular treatment proves to be an effective and decisive option for the treatment of bleeding in this type of injury.
Nilai Budaya dan Agama dalam Naskah “Kitab Mi’raj Kangjeng Nabi Muhammad saw.”
Authors: Fathurahmah Ani Tsania , Ruhaliah Ruhaliah , Koswara Dedi 
Published: December 2023

Abstrak: Penelitian ini bertujuan untuk mendeskripsikan naskah, menyusun edisi teks, menganalisis nilai budaya dan agama yang terdapat dalam naskah. Metode yang digunakan pada penelitian ini yaitu metode deskriptif analisis dengan menggunakan teknik wawancara dan studi pustaka. Sumber data dalam penelitian ini yaitu naskah “Kitab Mi’raj Kangjeng Nabi Muhammad saw.”. Proses edisi yang dilakukan yaitu dengan menggunakan edisi standar yakni dengan membetulkan kesalahan-kesalahan kecil dan ketidakajegan, sedang ejaannya disesuaikan dengan ketentuan yang berlaku. Berdasarkan hasil penelitian, naskah ini merupakan salah satu naskah dalam bentuk mikrofilm rol 34-05 yang ada di Pusat Studi Sunda yang isinya menceritakan mi’rajnya Kangjeng Nabi Muhammad saw. ke langit. Selain itu, dalam naskah ini juga terdapat beberapa nilai budaya dan agama. Nilai budaya yang terdapat pada naskah di antaranya: 1) sistem religi, 2) sistem kemasyarakatan, 3) sistem pengetahuan, 4) sistem bahasa, 5) kesenian, 6) mata pencaharian, dan 7) sistem teknologi. Sedangkan nilai agama yang terdapat pada naskah di antaranya: 1) akidah yang ditemukan berhubungan dengan keimanan (Rukun Iman); 2) syariah tentang salat, puasa, zakat, dan beberapa hukuman untuk manusia; dan 3) berhubungan dengan akhlak kepada Allah dan akhlak kepada sesama manusia. Kata Kunci: filologi; nilai agama; nilai budaya. Abstract: This research aims to describe the script, arrange text edition, analyze cultural and religious value in the manuscript. The method was used is descriptive of analysis by using interview technique and literature study. Edition process were used is standard edition, it fix small errors and inconsistencies, and the spelled according to the applicable provisions. The sources of data is manuscript of “Kitab Mi’raj Kangjeng Nabi Muhammad saw”. Based on the result, this script is one of microfilm rolls 34-05 in the center for Sundanese studies, which is the narrated of Mi’raj Kangjeng Nabi Muhammad saw to the heavens. In addition, in this text there are several cultural and religious values. The cultural values, namely: 1) religious system, 2) social system, 3) knowledge system, 4) language system, 5) art system, 6) livelihood system, and 7) technology system. While the religious values are: 1) aqidah is related to faith (six pillars of faith), 2) syariah about Shalat, fasting, zakat, and some punishment for humans, and 3) Morals is morals to Allah and morals to fellow human being.Keywords: cultural values; philology; religious values.
ASSESSING THE IMPACT OF CUTTING SEASON ON THE YIELD, ESSENTIAL OIL, AND COMPOSITION OF SPEARMINT CULTIVARS
Authors: YASAK Selma , TELCİ İsa 
Published: December 2023

The objective of this study was to assess the productivity, oil content, and composition of two spearmint species,
Mentha spicata and M. suaveolens, during different harvesting periods in the continental climate of the Lake
Region of Turkey. The study was conducted during at a two-year period, including both summer and autumn
cutting seasons in 2016 and 2017. The investigation revealed a significant increase in yields during the summer
harvest season. Carvone emerged as the predominant compound, with the exception of the Pinedo cultivar.
Carvone contents of the genotypic variations were from 28.0% to 51.0%, exhibiting heightened concentrations
during the initial harvest, followed by a subsequent reduction during the autumn harvest season. The major
components of the Pinedo was piperitenone oxide, accounting for 67.0% of the oil, and underwent a decline
during the autumn harvest.
Reformed Hermeneutics
Authors: Fourie Wynand 
Published: December 2023

Despite the Spirit-nature of Calvin’s hermeneutic, he does not provide the reader with either explanations or concrete examples of the way in which the Spirit is involved in the interpretation process (Nel 2020:8). In this article, I present a contribution to the ways in which the hermeneutical process of communal spiritual discernment during the council of Jerusalem, as recorded in Acts 15:1–35, can engage wit this aperture in Calvin’s hermeneutic. As an integral part of this communal spiritual discernment process, the engagement of the council, under the guidance of the Holy Spirit, with the biblical text is also highlighted. Reformed hermeneutics can, from the perspective of a process of communal spiritual discernment, be described as a hermeneutic that fits the occasion.

[1] Keener (2016:33 of 44) indicates that a Pentecostal hermeneutic is simply a Christian hermeneutic. Ultimately, a Christian hermeneutic is a Spirit hermeneutic.
EFFECT OF REMIFENTANIL BOLUS VS FENTANYL IN ATTENUATING HEMODYNAMIC RESPONSE IN VIDEOLARYNGOSCOPIC ENDOTRACHEAL INTUBATION
Authors: Jalal Shakho , Khudadad Amir 
Published: December 2023

Background Elevation of blood pressure and pulse rate are hemodynamic changes that occur during general anesthesia as a consequence of laryngoscopy and endotracheal intubation ETI, different laryngoscopies and many drugs have been tried to reduce these changes.
Objectives To evaluate and compare the efficacy of minimum dose of fentanyl and comparable remifentanil bolus dose during videolaryngoscopic ETI.
Patients and MethodsA triple blind randomized clinical trial implemented on 224 patients of age group between 16-65 years of either sex (ASA I and ASA II) scheduled for elective operation under general anesthesia with endotracheal intubation, they are randomly assigned into two groups, group A and group B representing both fentanyl and remifentanil as the drug preparation was unknown neither by the patient nor by the researcher and nor by the data analyser, in addition propofol two mg/kg and rocuronium 0.8 mg/kg were given then systolic blood pressure SBP, diastolic blood pressure DBP, mean arterial blood pressure MAP and heart rate HR were recorded in five different occasions as (T0) for baseline preinduction, (T1) one minute before ETI, (T2) one minute after ETI, (T3) three minutes after ETI and (T4) five minutes after ETI.
ResultsThere was a significant difference in the mean value of HR, SBP, DBP, MAP in both groups before, one, three and five minutes after endotracheal intubation with King vision videolaryngoscope KVVL and one μg/kg remifentanil bolus administration (group B) effectively showed substantial reduction in all hemodynamic parameters with significant statistical result (P < 0.05) when compared to intravenous IV fentanyl one μg/kg (group A).
ConclusionRemifentanil bolus of one μg/kg is better than intravenous fentanyl one μg/kg in attenuating hemodynamic response to ETI when KVVL used.
NURSES’ KNOWLEDGE AND ADHERENCE TO CLINICAL PRACTICE GUIDELINE TO PREVENT EXTRAVASATION OF CHEMOTHERAPY IN ERBIL CITY
Authors: Ismael Dler , Qadir Chnar , Mahmod Azaddin 
Published: December 2023

BackgroundKnowledge is the cornerstone of providing safe nursing care. However, to do so, they require access to the most recent clinical information and guidance.
ObjectivesThis study aimed to determine the nurses’ knowledge and adherence to clinical practice guidelines to prevent chemotherapy-related extravasation
Materials and MethodsDescriptive cross-sectional design was used, 70 oncology nurses who administer chemotherapeutic drugs were selected in both Rizgary Teaching Hospital and Nanakaly Hospital for blood disease in Erbil City, from June 2022 to May 2023, data was collected through a structured interview questionnaire consisting of demographic data of nurses, knowledge about extravasation of chemotherapy, adherence to clinical practical guideline and barrier adherence to clinical practical guideline, data analyzed by using mean, standard deviation, frequency, percentage, Chi-square and binary logistic regression were used to find out the result of the study, and, a p-value less than 0.05 is considered significant.
ResultsConcerning the overall level of knowledge of oncology nurses 55.7% had inadequate knowledge, 61.4% of them had low adherence to clinical practice guidelines, and the factors associated with low adherence to clinical practice guidelines was lower level of education (P-value=0.007, OR= 0.63), inadequate knowledge, (P-value= 0.041, OR=6.48), and high perceived barrier (P-value=0.004, OR= 9.87), the most commonly reported barriers was lack of continuing education to update nursing information and poor applicability of clinical practice guideline in real-world practice.
ConclusionThe clinical practice guideline adherence rate of nurses concerning chemotherapy administration was low because most oncology nurses had inadequate knowledge and high perceived barriers consequently the study highlighted the significance of continuing education to maintain oncology nursing staff with the updated evidence-based guidelines.
Infección por pasteurella multocida de herida por mordedura de gato: reporte de caso
Authors: Kozikova Valeriya , Agreda Orellana Ivanna Solmayra , Molina Matute Marcos Fernando 
Published: December 2023

Introducción: Pasteurella multocida, es una bacteria cocobacilar Gram negativa, forma parte de la microbiota oral de animales con capacidad infectiva en los seres humanos se transmite mediante mordeduras de animales de compañía como caninos y felinos ocasionando infecciones leves en forma de celulitis a graves. Los datos epidemiológicos relacionados con estas infecciones son escasos, así nace la necesidad del presente reporte de caso clínico.
Caso clínico: Paciente de 24 años de edad, acude a la casa de salud por molestias en la región metatarso falángica presentando edema, eritema y dolor con una sucesiva impotencia funcional, consecuencia de una mordedura ocasionada por un felino. Se le realiza una limpieza quirúrgica, radiografía y cultivo del líquido drenado del cual se aíslan colonias de Pasteurella multocida, estableciendo el tratamiento para la recuperación del paciente.
Conclusión: El diagnóstico de infecciones por mordeduras de animales incluyen la participación médica con la clínica del paciente, personal de radiología y del microbiólogo en la identificación del agente causal. El trabajo en conjunto de las áreas permite el diagnóstico oportuno y abordaje de la sintomatología del paciente, llevando al éxito terapéutico.
FLORES COMESTÍVEIS E COMPOSTOS BIOATIVOS: UMA REVISÃO DA LITERATURA
Authors: Rinaldi Machado Lentz Katiana 
Published: December 2023

O artigo tem como tema principal o consumo de flores comestíveis como possíveis alimentos benéficos. Existem diversas flores que são comestíveis, as elas possuem compostos bioativos que podem ofertar benefícios para a saúde. Nesse sentido, pode-se considerar como uma nova alternativa dietética, também como uma forma de variar o consumo desses compostos, que, por sua vez, auxiliam na prevenção de doenças por conterem propriedades antioxidante e anti-inflamatórias.
Questão problema que orienta o artigo é pesquisar os possíveis benefícios e quais flores comestíveis podem ser inseridas na alimentação como uma alternativa benéfica para a saúde? Objetivo geral da pesquisa é identificar quais são os benefícios da inserção de flores na alimentação. E os objetivos específicos são contextualizar acerca dos estudos realizados sobre flores como alimentos e seus possíveis benefícios a saúde, descrever sobre as principais flores que servem como alimento e trazem benefícios a saúde e explicitar seus compostos ativos.
Flores comestíveis, isto é, aquelas que podem ser ingeridas, e são alternativas de alimentação funcional, por conterem compostos bioativos que proporcionam qualidade de vida para os que a consomem.
Os compostos bioativos são nutrientes essenciais para o bom funcionamento do organismo, encontrados nos vegetais de diferentes espécies, sendo as flores uma diversidade destas fontes, ainda pouco explorada.
A pesquisa é uma revisão bibliográfica, feita por meio de coleta de dados em base de dados acadêmicas, como no Portal Regional da BVS, Portal Saúde Baseada em Evidências, Pubmed, artigos e revista científicas, em língua portuguesa e língua inglesa, com recorte de tempo de 10 anos e os critérios para seleção serão de verificar nos resumos dos estudos se estes vão ao encontro do tema pretendido no estudo.
Yüksek SYNTAXII skoru olan koroner arter hastalarında plazma aterojenik indeksinin rolü
Authors: NURKOÇ Serdar Gökhan 
Published: December 2023

Amaç: Koroner arter hastalığına (KAH) göre aterojenik plazma indeksinin (AIP) en iyi tanısal eşik değerini ve bunun SYNTAX II (SYNergy between percutaneous coronary intervention with TAXus and cardiac surgery) skoru (SSII) ile ilişkisini değerlendirmeye çalıştık.
Gereç ve Yöntemler: Araştırma, koroner anjiyografi uygulanan, ST segment yükselmesiz miyokard enfarktüsü (NSTEMI) olan ve en az iki bağımsız kardiyolog tarafından ilk koroner anjiyografiye dayalı olarak SSII'nin hesaplandığı ardışık 280 hastayı kapsamıştır. Hastalar düşük SSII (
Bariatrik cerrahi sonrası abdominoplastide komplikasyonlara neden olan prediktif faktörler
Authors: ÖZTÜRK Doğan , ÖZTÜRK Bülent 
Published: December 2023

Amaç: Abdominoplasti günümüzde giderek popüler bir prosedür haline gelmiştir. Hasta için yüz güldürücü sonuçları olmasının yanında, operasyon sonrası bazı istenmeyen sonuçlar da ortaya çıkabilmektedir. Bu çalışmanın amacı, abdominoplasti sonrası gelişen komplikasyonları irdelemek ve olası risk faktörlerinin komplikasyonlarla ilişkisini ortaya koymaktır.
Abdominoplastinin lokal ve sistemik komplikasyonlarını etkileyen faktörler literatürde yeterince tanımlanmamıştır Abdominoplasti güvenli ve çok popüler olmasına rağmen, bu prosedür diğer vücut şekillendirme yöntemleriyle karşılaştırıldığında komplikasyonlara açık bir yöntemdir.
Gereç ve Yöntemler: Atatürk Sanatoryum Eğı̇tı̇m ve Araştırma Hastanesı̇nde Şubat 2020 ı̇le Şubat 2022 tarı̇hlerı̇ arasında barı̇atrı̇k cerrahı̇ sonrası abdomı̇noplastı̇ uygulanan 95 hastanın (81 kadın ve 14 erkek) verileri retrospektif olarak incelendi. 95 hastanın yaş,cı̇nsı̇yet, BMİ, verı̇len kı̇lo, diabetetesmellitus,hipertansiyon, sigara içimi mevcudiyeti ve bunların komplı̇kasyonlarla ilişkisi analı̇z edı̇ldi. Olası risk faktörleri ve gelişen komplikasyonlar arasındaki ilişki İndependent Sample T Test ve Ki-Kare analizi kullanılarak araştırılmıştır. İncelenen risk faktörleri yaş, cinsiyet, vücut kitle indeksi, sigara içme öyküsü, diabetesmellitus öyküsü, hipertansiyon öyküsü, abdominoplasti ameliyat tekniğidir.
Bulgular: Abdominoplasti yapılan 95 hastanın 27’sinde (%28,42) lokal ve sistemik komplikasyonlar gelişti. En sık görülen komplikasyon, 16 hastada saptanan seromaydı (%16.84). Sırasıyla 4 hastada yara yeri enfeksiyonu (%4.21), 1 hastada cilt nekrozu (%1), 2 hastada yara ayrılması (%2.1) ve 2 hastada hematom (%2.1), 2’sinde de pulmonertromboemboli (%2.1) gelişti.
Sonuçlar: Komplikasyon oranını önemli ölçüde artıran faktörler, artmış vücut kitle indeksi (p =0.002) ve sigara içme öyküsüydü (p = 0.004). Bu parametreler komplikasyon oluşumunda istatiksel olarak anlamlıydı. Diğer parametrelerde ise istatiksel anlamlılık saptanamadı.
The value of using a storybook to protect the psychological health of children during COVID-19 in resource-limited communities
Authors: Mthembu Maude , Raniga Tanusha , Boecker Michael 
Published: December 2023

Globally, the COVID-19 pandemic has caused poor mental health, parental loss and food insecurity in children. At the peak of the pandemic, context-relevant and child-friendly COVID-19 tools for child counselling and education were limited in low-income communities. Researchers and social work practitioners created Uhambo Lwami storybook in IsiZulu language to initiate conversations with children about COVID-19. The findings reported are drawn from in-depth interviews with 13 purposively selected community-based social workers and child and youth workers who integrated the storybook into child counselling during the pandemic. The central premise of the paper is their experiences about the use and value of the storybook to support children’s psychological well-being during the pandemic. Two themes are discussed: The use of the storybook with children and its value to support children during the pandemic. The results indicated that the storybook created a child-friendly environment for children to share their psychosocial experiences of living during the pandemic. Furthermore, it facilitated sharing of experiences about death and illness in a caring and responsive manner. Well-designed storybooks are a cost-effective tool useful to initiate sensitive discussions with children. Context-relevant storybooks can be used to educate and alleviate distress in children during pandemics.
Yoğun bakım ünitesine yatış anında basınç ülseri olan ve yatışı sırasında basınç ülseri gelişen hastaların karşılaştırılması
Authors: GÖNDEREN Kamil , GÖNDEREN Aysun , SİMAVLIOĞLU Gülşen , İDİL Duygu 
Published: December 2023

ÖZ
Amaç: Bası yaraları yoğun bakım ünitelerinde (YBÜ) sık görülen, hastanede yatış süresini uzatan, mortaliteyi arttıran ve tedavi giderlerini yükselten bir sağlık sorunudur
Gereç ve Yöntemler: Çalışmaya 01.09.2017–28.02.2019 tarihleri arasında İç Hastalıkları YBÜ’de 24 saatten uzun süreli izlenen hastalar dahil edilmiştir. Hastalara ait veriler hemşire ve doktor izlem kayıtlarından retrospektif olarak elde edilmiştir. Hastaların demografik ve klinik özellikleri; yoğun bakım ünitesine kabülde basınç ülseri varlığı, bası yarasının, derecesi, Braden bası yarası risk skorlaması veriler değerlendirilmiştir. Yoğun bakım takibinde basınç ülseri gelişen ve yoğun bakım yatışı anında basınç ülseri olan hastalar karşılaştırılmıştır.
Bulgular: Elli dokuz hastanın yoğun bakım kabulünde bası yarası mevcut iken, izlem sırasında 24 hastada yeni bası yarası gelişmiştir. Yoğun bakım ünitesine yatışı sırasında basınç ülseri gelişen hastalar, yoğun bakıma yatış anında basınç ülseri olan hastalar göre daha uzun yoğun bakım yatışı ve daha uzun mekanik ventilatörde kalma süresine sahip bulunmuşturher iki grubun da mortalite oranları yüksek saptanmıştır.
Sonuç: Çalışmada, basınç ülserinin hastane içi veya hastane dışında gelişmesine bağlı olmaksızın mortalitesi yüksek ve önlenmesi gereken bir durum olduğu gösterilmektedir.
BAGAIMANA MUKA DIWUJUDKAN DALAM INTERAKSI KOMUNIKASI PADA PERTUNJUKAN WAYANG SUKURAGA
Authors: Sukmawan Ramdan 
Published: December 2023

<p>This research aims at describing how face expresses in communication interaction in wayang sukuraga show. The show which presents the theme of human conflict internally, namely the conflicts part of body between figure and figure such as eyes, mouth, ears, nose, hand, and foot will have a certain offering of face whether positive face or negative face. Positive face expresses in: (1) regretting to what happen; (2) want to be liked; (3) confessing on profession; and (4) want to be known by other. Meanwhile negative face expresses in: (1) freedom to choose by his/herself; (2) freedom to see; (3) freedom to take; and (4) order to find out. The Research applied qualitative descriptive method with pragmatics approach. The data was obtained from video of wayang sukuraga show. Data collection applied <em>simak</em> method. The technique applied <em>sadap</em> and <em>catat</em>. Qualitative data analysis applied with the step of reduction data, display data, and drawing conclusion. </p><p><em><br /></em><em></em></p>