bluuebunny/crossref_metadata_2025_split huggingface dataset:
Winter warm spells over Italy: Spatial–temporal variation and large‐scale atmospheric circulation
Authors: Di Bernardino Annalisa , Iannarelli Anna Maria , Casadio Stefano , Siani Anna Maria 
Published: February 2024

AbstractThis article analyses the winter warm spells (WWS) that occurred in central Mediterranean over the period 1993–2022, examining the daily maximum temperatures collected at eight airport sites located in the Italian Peninsula, belonging to different climate zones. According to the definition proposed in 1999 by the Expert Team on Climate Change Detection and Indices (ETCCDI), a WWS is a sequence of at least six consecutive days when daily maximum air temperature exceeds the calendar day 90th percentile centred on a 5‐day window for a base period. WWS occurring over the entire Italian territory or only over northern/central/southern Italy have been identified and related to the peculiar synoptic conditions. It was found that December is the month most prone to WWS and, on average, WWS last 9.4 days in northern Italy, 6.6 days in central Italy, and 8.5 days in southern Italy. Over the period under investigation, the Italian Peninsula experienced only one common event characterized by persistent high‐pressure systems associated with air subsidence over western Mediterranean and, therefore, with exceptional warming. Finally, it has been proven that the definition of WWS proposed by ETCCDI allows to capture synoptic scale events but, in orographically complex areas such as Italy, underestimates moderate spells, which generally might have a duration of at least 3 days. Consequently, it is important to consider the possibility of reducing the period length threshold used for the detection of WWS when orographically heterogeneous regions are studied.
Phytochemical profiling of red raspberry (Rubus idaeus L.) honey and investigation of compounds related to its pollen occurrence
Authors: Leoni Valeria , Panseri Sara , Giupponi Luca , Pavlovic Radmila , Gianoncelli Carla , Coatti Gloria , Beretta Giangiacomo , Giorgi Annamaria 
Published: February 2024

AbstractBACKGROUNDRed raspberry (Rubus idaeus L.) is an important nectar source for honey production in some specific habitats as well as an important crop, so the definition of the features of this kind of honey is noteworthy. However, due to its rarity on the market, red raspberry honey is poorly characterized. The aim of this work was the phytochemical characterization of honey containing red raspberry from different geographical origins, through melissopalynological analyses concurrently with untargeted metabolomics achieved with different chromatographic techniques coupled to mass spectrometry: solid‐phase micro‐extraction/gas chromatography/mass spectrometry (SPME‐GC–MS) and high‐performance liquid chromatography/Orbitrap mass spectrometry (HPLC‐Orbitrap).RESULTSOnly 4 out of the 12 samples involved in the study contained raspberry pollen as dominant pollen, although these honeys did not group in the hierarchical cluster analysis nor in the classical multidimensional scaling analyses used for data evaluation. The first result was the detection of mislabelling in two samples, which contained raspberry pollen only as minor or important minor pollen. Of the 188 compounds identified by HPLC‐Orbitrap and of the 260 identified by SPME‐GC–MS, 87 and 31 compounds were present in all samples, respectively. The structurally related compounds nicotinaldehyde and nicotinamide, nicotinic acid and nicotinyl alcohol were present in 100% of the samples and correlated with R. idaeus pollen count (r > 0.60, Pearson's correlation analysis).CONCLUSIONThis study reveals important aspects about the characterization of red raspberry honey and could give new insights on bee diet and preferences, since niacin compounds resulted interestingly to be related to the presence of red raspberry pollen. © 2024 Society of Chemical Industry.
Surgical treatment of distal hamstring tendon injuries yield a higher return‐to‐sports rate: A systematic review
Authors: Marín Fermín Theodorakys , Aminake Ghislain , Vasiliadis Angelo V. , Kalifis Georgios , Grabowski Radoslaw , Macchiarola Luca , Al‐Dolaymi Ayyoub A. 
Published: February 2024

AbstractPurposeThe purpose of this study is to compare the patient‐reported outcomes and return to sports of the conservative and surgical treatment of distal hamstring tendon injuries.MethodsFollowing the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses guidelines, two reviewers searched PubMed, Scopus and Virtual Health Library databases in January 2023. Clinical studies evaluating conservative or surgical management outcomes of distal hamstring tendon injuries were considered eligible for this systematic review if predefined criteria were fulfilled: (1) published in English or Spanish; (2) evaluated any of the following: patient‐reported outcomes, return‐to‐sports rate (RTS‐R) or return‐to‐sports time (RTS‐T). Data were presented in tables using absolute values from individual studies and derived pooled percentages.ResultsEighteen studies were included for 67 patients and 68 distal hamstring tendon injuries. Initially, 39 patients (58.2%) underwent surgical treatment, whereas 28 (41.8%) were treated conservatively. Among conservative treatment patients, 15 failed and had to be operated on (53.6%), all with distal semitendinosus tendon injuries. Anchor fixation was the technique of choice in 20 lesions (36.4%), tenodesis in 16 (29.1%), tenectomy in 14 (25.5%) and sutures were preferred in five (9%). Thirteen out of 28 patients (46.4%) undergoing initial conservative treatment returned to sports at a mean of 3.6 months (range 1 week to 12 months), in contrast to surgical treatment, in which 36 out of 39 patients (92.3%) returned at a mean of 4.2 months (range 6 weeks to 12 months). Additionally, 14 of 15 patients (93.3%) converted to surgical treatment after failed conservative treatment returned to sports at a mean of 7.6 months after injury.ConclusionInitial surgical treatment of distal hamstring tendon injuries yields a high RTS‐R (92.3%) at a mean of 4.2 months. Furthermore, 15 out of 28 patients (53.6%) initially treated conservatively had to be operated on, delaying the RTS‐T (mean 7.6 months after injury) without affecting their RTS‐R.Level of EvidenceIV.
An All‐Colloidal and Eco‐Friendly Quantum‐Dot Laser
Authors: Wu Yuting , Cai Wenbing , Huang Zhigao , Ren Yinjuan , Wu Yiming , Wang Yue 
Published: February 2024

AbstractColloidal zinc‐chalcogenide quantum dots (QDs) are emerging as the promising heavy‐metal‐free light–emitters, however, the development of light amplification and lasing therein remains challenging. Here, corroborated by comprehensive in situ and transient spectroscopy, it is unraveled that the ultrafast photooxidization‐induced trapping process (≈2 ps) and the sub‐bandgap photoinduced absorption under intense excitation are the main hindrances to light amplification in ZnSeTe QDs. Upon tackling the hurdle by heterostructure engineering, this study demonstrates that the ZnSeTe QDs exhibit intrinsically superior gain performance, including the high gain cross‐section (5.6 × 10−16 cm2), long gain lifetime (615 ps), low pump threshold (≈25.9 µJ cm−2) and high fatigue resistance. On this basis, a microfluidic channel is designed to mass‐produce the micellar cavities whose surfaces are treated to combine with the ZnSeTe QDs. The active QD‐micelle hybrids show state‐of‐the‐art lasing performance and allow the fiber‐based micro‐manipulation toward the single‐mode lasers. These findings not only provide essential knowledge on the gain physics in ZnSeTe QDs, but also open a new avenue to develop high‐performance eco‐friendly lasers.
Plasmonic Architectures Boosting Performance in Terahertz Photodetectors
Authors: Zhang Kaixuan , Han Li , Hu Zhen , Xiao Kening , Jiang Mengjie , Yu Anqi , Pan Xiaokai , Wang Dong , Zhang Libo , Lv Xuyang , Tian Shijian , Lan Shiqi , Xing Huaizhong , Zhang Ning , Politano Antonio , Wang Lin 
Published: February 2024

AbstractIn terahertz (THz) photodetection, the efficient interaction between light and matter is crucial for enhancing material properties in nonequilibrium states. This work introduces an innovative approach using spiral plasmonic architectures to effectively control inversion‐symmetry coupling, promoting the operational efficiency of light‐induced hot‐carrier effects in the THz band. The strategic design of the spiral structures, focusing on chirality and symmetry, enables the successful manipulation of a self‐driven photocurrent, adapting its direction and magnitude as needed. This design facilitates the improvement of THz detectors in terms of sensitivity and responsiveness. Additionally, the integration of asymmetric metallization and black phosphorus in the detectors has achieved noteworthy performance metrics, such as a maximum responsivity of 70.2 V W−1 at 0.30 THz, a fast response time below 6 µs, and a noise‐equivalent power lower than 1.95 × 10−10 W Hz−1/2. Harnessing the potential of light‐induced hot carrier effects and advanced band‐structure engineering, this research offers a pragmatic approach for the development of high‐efficiency THz photodetectors, opening new avenues for applications like remote sensing and rapid imaging.
Causal discovery to understand hot corrosion
Authors: Varghese Akhil , Arana‐Catania Miguel , Mori Stefano , Encinas‐Oropesa Adriana , Sumner Joy 
Published: February 2024

AbstractGas turbine superalloys experience hot corrosion, driven by factors including corrosive deposit flux, temperature, gas composition, and component material. The full mechanism still needs clarification and research often focuses on laboratory work. As such, there is interest in causal discovery to confirm the significance of factors and identify potential missing causal relationships or codependencies between these factors. The causal discovery algorithm fast causal inference (FCI) has been trialled on a small set of laboratory data, with the outputs evaluated for their significance to corrosion propagation, and compared to existing mechanistic understanding. FCI identified salt deposition flux as the most influential corrosion variable for this limited data set. However, HCl was the second most influential for pitting regions, compared to temperature for more uniformly corroding regions. Thus, FCI generated causal links aligned with literature from a randomised corrosion data set, while also identifying the presence of two different degradation modes in operation.
Evaluation of coated steels in supercritical CO2
Authors: Pint Bruce A. , Pillai Rishi , Su Yi‐Feng , Lance Michael J. , Keiser James R. 
Published: February 2024

AbstractThe carburizing supercritical CO2 (sCO2) environment limits the use of lower cost steels in the lower temperature (450–650°C) portions of the sCO2 Brayton cycle because of concerns about internal carburization and embrittlement. Results on a ferritic–martensitic steel and conventional and advanced austenitic steels at 450–650°C in 30 MPa sCO2 with and without 1% O2 and 0.1% H2O additions have indicated that sCO2 environments will have lower maximum operating temperatures compared to steam plants. Pack Al and Cr coatings were evaluated at 650°C on T91 and 316H substrates and showed some benefit for up to 2000 h at 650°C, especially without impurities. However, characterization indicated Al2O3 was not formed and Cr‐rich carbides formed in the Cr coatings. With the addition of impurities in the sCO2, the coatings were less protective at 650°C. Subsequent exposures at 600°C in sCO2 showed similar behavior. Postexposure evaluations included measuring the bulk C content and room temperature tensile properties. Improvements were indicated but the tensile results were complicated by the high temperature pack coating process affecting the substrate properties.
A pH/Redox Dual‐Responsive Nanocarrier for Hypoxia‐Activated Prodrug and Anticancer Prodrug in Cancer Treatment
Authors: Ho Jhin Chen , Chen Ching‐Yi 
Published: February 2024

AbstractTumor microenvironment heterogeneity (TMH) remains a challenge in cancer treatment. Nanocarrier prodrugs based on small‐molecular drug or macromolecular drug conjugates emerge as an efficient approach for multidrug delivery at tumor sites and activating the prodrugs by endogenous stimuli resulting from TMH. Herein, a redox/pH dual‐sensitive micelle conjugated is developed via disulfide linkage with naphthalimide‐based prodrug (PNA), assigned as PDM to encapsulate hypoxia‐activated prodrug, banoxantrone (AQ4N), for combination therapy. These micelles have several interesting features, including sufficiently stable with less drug release under physiological conditions and dual stimuli‐triggered intracellular release, high drug loading content, and negligible cytotoxicity. More importantly, in vitro cytotoxicity of AQ4N‐loaded PDM micelles exhibits a combinational anticancer efficacy between chemotherapy of PNA and hypoxia‐activated chemotherapy of AQ4N under hypoxic conditions. Moreover, the developed PNA as a new chemotherapeutic drug displays good therapeutic efficiency and fluorescent properties, which can be used for monitoring drug release in real time. This study not only offers an attractive strategy for an effective combination of traditional chemotherapy and hypoxia‐activated chemotherapy, but also provides an important concept to develop dual stimuli‐sensitive prodrug nanoplatform targeting for endogenous TMH.
Anatomical features of a crossing vein connecting left and right internal mammary veins: A preliminary study with computerized tomography or magnetic resonance imaging
Authors: Ueno Mayu , Mori Hiroki , Uemura Noriko , Kato Sayuri , Tanaka Kentaro 
Published: February 2024

AbstractBackgroundIn breast reconstruction with free flaps, retrograde venous anastomosis into the internal mammary vein (IMV) is often unavoidable. Utility of a crossing vein between the right and left IMV, one of the anatomical foundations which make retrograde flow possible, has been reported but only with a few detailed features. This study evaluated the presence, actual location, and diameter of the crossing veins using preoperative imaging such as contrast‐enhanced computed tomography (CECT), or contrast‐enhanced magnetic resonance imaging (CEMRI). Moreover, this is a preliminary non‐invasive study to clarify these processes on a larger scale.MethodsWe included 29 cases of unilateral breast reconstruction performed between July 2018 and September 2023 at our institution using unipedicled or bipedicled free deep inferior epigastric artery perforator (DIEP) flaps with retrograde venous anastomosis to only one IMV at the level of anastomosis. No congestion or necrosis was observed. In the final 24 cases with sufficient imaging coverage of preoperative contrast‐enhanced images (15 CECT and 9 CEMRI), the crossing veins of IMVs were detected and the number, localization, and diameter were measured.ResultsIn 20 cases of 24 images, the crossing veins between IMVs were completely identified (83%). In 18 of the cases, only one crossing vein was established immediately ventral to the xiphoid process, averaging 19.3 ± 7.18 mm caudal to the fibrous junction between the sternal body and xiphoid process. The average diameter of the veins was 1.57 ± 0.42 mm. In two other cases, the second crossing vein originated on the dorsal surface of the sternum, but it was a very thin vein of about 0.4 mm. Three images indicated incomplete identification of the crossing vein at the xiphoid process, and in one case, no crossing vein was observed between bilateral IMVs.ConclusionThe contrast‐enhanced imaging study revealed an anatomic feature that the crossing veins (about 1.5 mm in diameter) connecting the right and left IMVs are located just ventral to the xiphoid process. Furthermore, the crossing veins can be identified on contrast‐enhanced images, and refinement of this method is expected to lead to future non‐invasive anatomical investigations in an even larger number of cases.
A tightly‐coupled planar absorber with broadband and wide‐angle
Authors: Chen Zhi , Lin Xian Qi , Yang Xinmi , Fan Yu Lu , Kang Yu Xin 
Published: February 2024

AbstractMost planar absorbers are designed under normal incidence, leading to a sharp decline in absorber performance under oblique incidence, especially when the incidence angle exceeds 30°. Three‐dimensional structured absorbers ensure the performance of the absorber under oblique incidence, but they lack practicality due to their complex processing and assembly. In this letter, a tightly‐coupled planar absorber (TCPA) is proposed. Its design method combines the reciprocity principle and tightly‐coupled structure, incorporating a wide‐angle matching layer and interdigitated structures to improve planar absorber's performance under oblique incidence. A sample is fabricated and measured for verification. The measurement results show that the absorber has a fractional bandwidth of 102.0% with an absorption rate of at least 90% under normal incidence. When the incident angle reaches 50°, the absorber maintains good performance under both transverse electric and transverse magnetic polarization.
Inverse design of reflective metasurface antennas using deep learning from small‐scale statistically random pico‐cells
Authors: You Xi Chong , Lin Feng Han 
Published: February 2024

AbstractA small‐scale data‐selection method is proposed for deep‐learning‐based inverse design of reflective metasurface antennas (MAs). The overall design process involves discretization, coding, data selection, simulation, feature representation, training, prediction, and metasurface design. Unlike conventional method that selects the training data empirically after simulation from a large quantity of unit cells, the proposed statistically random data filtering (SRDF) method selects the training data set randomly before simulation by leveraging the geometric‐coding statistics of the unit cells. The advantages of the proposed data‐selection method include lower simulation cost (due to fewer simulations needed), improved generality, and higher design accuracy simultaneously. The design process starts from the discretization of a unit cell into a grid array of binaurally‐coded pico‐cells. Afterwards, the proposed SRDF method selects 0.01% of all the possible unit cells for simulation. With the simulated results, a deep‐convolutional‐variational‐autoencoder network is trained, leading to an accurate and bidirectional prediction of both the geometry and reflection phase of a unit cell in seconds. The proposed data‐selection method is validated by designing two reflective MAs with the predicted unit cells, each pointing a pencil beam off the boresight by 30° and 60°, respectively. Experiments are in line with full‐wave simulations.
Any‐nucleus distributed active programmable transmit coil
Authors: Han Victor , Reeder Charlie P. , Hernández‐Morales Miriam , Liu Chunlei 
Published: February 2024

AbstractPurposeThere are 118 known elements. Nearly all of them have NMR active isotopes and at least 39 different nuclei have biological relevance. Despite this, most of today's MRI is based on only one nucleus—1H. To facilitate imaging all potential nuclei, we present a single transmit coil able to excite arbitrary nuclei in human‐scale MRI.Theory and MethodsWe present a completely new type of RF coil, the Any‐nucleus Distributed Active Programmable Transmit Coil (ADAPT Coil), with fast switches integrated into the structure of the coil to allow it to operate at any relevant frequency. This coil eliminates the need for the expensive traditional RF amplifier by directly converting direct current (DC) power into RF magnetic fields with frequencies chosen by digital control signals sent to the switches. Semiconductor switch imperfections are overcome by segmenting the coil.ResultsCircuit simulations demonstrated the effectiveness of the ADAPT Coil approach, and a 9 cm diameter surface ADAPT Coil was implemented. Using the ADAPT Coil, 1H, 23Na, 2H, and 13C phantom images were acquired, and 1H and 23Na ex vivo images were acquired. To excite different nuclei, only digital control signals were changed, which can be programmed in real time.ConclusionThe ADAPT Coil presents a low‐cost, scalable, and efficient method for exciting arbitrary nuclei in human‐scale MRI. This coil concept provides further opportunities for scaling, programmability, lowering coil costs, lowering dead‐time, streamlining multinuclear MRI workflows, and enabling the study of dozens of biologically relevant nuclei.
Survivors of infant atypical teratoid/rhabdoid tumors present with severely impaired cognitive functions especially for fluid intelligence and visual processing: data from the German brain tumor studies
Authors: Traunwieser Thomas , Loos Elena , Ottensmeier Holger , Gastberger Katharina , Nemes Karolina , Mynarek Martin , Bison Brigitte , Kandels Daniela , Neumayer Petra , Neumann‐Holbeck Anne , Lüttich Peggy , Baust Katja , Faulstich‐Ritter Kristin , John Rainer , Kreisch Andrea , Landmann Judyta , Manteufel Eva , Nest Alexandra , Prüfe Jenny , Schubert Lisa , Stamm Walther , Timmermann Beate , Gerss Joachim , Rutkowski Stefan , Schlegel Paul‐Gerhardt , Eyrich Matthias , Gnekow Astrid K. , Frühwald Michael C. 
Published: February 2024

AbstractBackgroundThe contribution of tumor type, multimodal treatment, and other patient‐related factors upon long‐term cognitive sequelae in infant brain tumor survivors remains undefined. We add our retrospective analysis of neuropsychological and quality of survival (QoS) outcome data of survivors of atypical teratoid/rhabdoid tumors (ATRT) and extracranial malignant rhabdoid tumors of the soft tissues (eMRT) and kidneys (RTK) treated within the same framework. Neuropsychological data from children with ATRT were compared to data from children with non‐irradiated low‐grade glioma (LGG).Patients and methodsFollowing surgery, patients (0–36 months at diagnosis) had received radio‐chemotherapy (up to 54 Gy; ATRT: n = 13; eMRT/RTK: n = 7), chemotherapy only (LGG: n = 4; eMRT/RTK: n = 1) or had been observed (LGG: n = 11). Neuropsychological evaluation employing comparable tests was performed at median 6.8 years (ATRT), 6.6 years (eMRT/RTK), and 5.2 years (LGG) post diagnosis.ResultsWe detected sequelae in various domains for all tumor types. Group comparison showed impairments, specifically in fluid intelligence (p = .041; d = 1.11) and visual processing (p = .001; d = 2.09) in ATRT patients when compared to LGG patients. Results for psychomotor speed and attention abilities were significantly below the norm for both groups (p < .001–.019; d = 0.79–1.90). Diagnosis predicted impairments of cognitive outcome, while sex‐ and age‐related variables did not. QoS outcome for all rhabdoid patients displayed impairments mainly in social (p = .008; d = 0.74) and school functioning (p = .048; d = 0.67), as well as lower overall scores in psychosocial functioning (p = .023; d = 0.78) and quality of life (p = .006; d = 0.79) compared to healthy controls.ConclusionSurvivors of infant ATRT experience various late effects in cognition and QoS following multimodal treatment, while infant LGG patients without radiotherapy demonstrated comparable impairments in psychomotor and attention abilities. Early onset and multimodal treatment of rhabdoid tumors require close monitoring of neuropsychological and QoS sequelae.