bluuebunny/crossref_metadata_2025_split huggingface dataset:
Interleukin-4 during post-exercise recovery negatively correlates with the production of phagocyte-generated oxidants
Authors: Chmielecki Adam , Bortnik Krzysztof , Galczynski Szymon , Kopacz Karolina , Padula Gianluca , Jerczynska Hanna , Stawski Robert , Nowak Dariusz 
Published: December 2023

Exhaustive run induced a biphasic oxidative response of circulating phagocytes in 16 amateur sportsmen. The first phase involved an increment just after exercise of enhanced whole blood chemiluminescence normalized per phagocyte count, whereas in the second phase a decrement from 1 h post-exercise and ongoing till 24 h. We tested whether plasma Interleukin IL-4, IL-8, IL-10 and Tumor Necrosis Factor α concentrations change in response to exhaustive run and whether there are associations between their levels and delta resting. Moreover, IL-8 and IL-10 significantly increased immediately post-exercise and after 1 h, but later normalized. Tumor necrosis factor α rose by 1.1-times only just after exercise. However, none of these cytokines showed any correlation with the investigated chemiluminescence. Exercise did not alter plasma concentrations of IL-4. However, pre-exercise IL-4 negatively correlated with measured luminescence just after exercise (ρ = −0.54, p &lt; 0.05), and also tended to be negatively associated with decrements of the second phase at 1 h post-exercise ρ = −0.45, p = 0.08. It is suggested that plasma IL-4, by a negative association with blood phagocytes oxidants production, could be involved in the maintenance of proper balance between oxidants and anti-oxidants during strenuous exercise and post-exercise recovery.
“I could do almost nothing without digital technology”: a qualitative exploration of adolescents’ perception of the risks and challenges of digital technology
Authors: Bitto Urbanova Laura , Madarasova Geckova Andrea , Dankulincova Veselska Zuzana , Capikova Silvia , Holubcikova Jana , van Dijk Jitse P. , Reijneveld Sijmen A. 
Published: December 2023

BackgroundThe fast development of digital technology and of its use at even younger ages is significantly shaping the current generation of adolescents. This is leading to an almost unlimited accessibility that provides a large number of opportunities, but also to many challenges that adolescents have to face. The aim of our study was to explore the perceptions adolescents have of the risks of digital technology.MethodsWe conducted online semi-structured interviews as a part of the international Health Behaviour in School-aged Children study. The sample consisted of 15 Slovak adolescents (mean age: 15.33; 20% boys). To analyse our data, we used consensual qualitative research and thematic analysis.FindingsOur findings confirmed that adolescents are aware of the risks associated with the use of digital technology. Regarding their specific types of the perceived risks, we identified four main themes: 1. dependence on the functionality of technology; 2. problematic control; 3. vulnerability in the virtual environment; 4. health risks. Adolescents thus want technology that is functional, safe and does not endanger their health.ConclusionDespite the fact that adolescents know of the risks they may experience due the digital technology, they still use it. Preventive strategies should focus on functionality, safety and healthiness; furthermore, they should support the constant development of adolescents’ digital awareness and raising their awareness about effective and non-threating use of technology.
Guilt, shame, and embarrassment: similar or different emotions? A comparison between Italians and Americans
Authors: Giorgetta Cinzia , Strappini Francesca , Capuozzo Alessandra , Evangelista Elisa , Magno Antonella , Castelfranchi Cristiano , Mancini Francesco 
Published: December 2023

IntroductionGuilt, shame, and embarrassment represent affective experiences with social implications and diverse self-relevant negative affect. While the distinction between these emotion terms has been extensively investigated, little is known about how they diverge and are related to each other and their crosscultural differences.MethodsHere, we used a community sample (N = 163) comprised of Americans and Italians and a scenario-based measure in which we asked participants to report the intensity of emotions that the story’s main character would feel. The elements used to build the scenarios were based on a recent theoretical approach that proposes distinguishing cognitive, somatic, interoceptive, and behavioral ingredients to differentiate between these emotions. We hypothesized that these ingredients might effectively elicit the target emotions and that the main differences across these cultures would be associated with the emotion terms of shame/vergogna.ResultsOur findings suggest that these defining elements are effective in evoking experiences of guilt, shame, and embarrassment. Moreover, we found that shame was equally elicited by the Shame and Guilt Scenarios only in the American sample, thus suggesting a proximity between shame and guilt in the American sample compared to the Italian’s terms of vergogna and colpa.DiscussionThese results suggest important implications for the psychology of moral emotions and highlight the importance of taking into account some cognitive factors, such as the quality of self-evaluation, the discrepancy between the actual self and the ideal self vs. the sense of perceived responsibility, and the different domains related to self-esteem.
Identifying complementary and alternative medicine recommendations for anxiety treatment and care: a systematic review and critical assessment of comprehensive clinical practice guidelines
Authors: Zhao Fei-Yi , Kennedy Gerard A. , Xu Peijie , Conduit Russell , Wang Yan-Mei , Zhang Wen-Jing , Wang Hui-Ru , Yue Li-Ping , Huang Yu-Ling , Wang Yin , Xu Yan , Fu Qiang-Qiang , Zheng Zhen 
Published: December 2023

BackgroundClinical practice guidelines (CPGs) are used to guide decision-making, especially regarding complementary and alternative medicine (CAM) therapies that are unfamiliar to orthodox healthcare providers. This systematic review aimed to critically review and summarise CAM recommendations associated with anxiety management included in the existing CPGs.MethodsSeven databases, websites of six international guidelines developing institutions, and the National Centre for Complementary and Integrative Health website were systematically searched. Their reporting and methodological quality were evaluated using the Reporting Items for practice Guidelines in Healthcare checklist and the Appraisal of Guidelines for Research and Evaluation (2nd version) instrument, respectively.ResultsTen CPGs were included, with reporting rates between 51.4 and 88.6%. Seven of these were of moderate to high methodological quality. Seventeen CAM modalities were implicated, involving phytotherapeutics, mind–body practice, art therapy, and homeopathy. Applied relaxation was included in 70% CPGs, which varied in degree of support for its use in the treatment of generalised anxiety disorder. There were few recommendations for other therapies/products. Light therapy was not recommended for use in generalised anxiety disorder, and St John’s wort and mindfulness were not recommended for use in social anxiety disorder in individual guidelines. Recommendations for the applicability of other therapies/products for treating a specific anxiety disorder were commonly graded as “unclear, unambiguous, or uncertain”. No CAM recommendations were provided for separation anxiety disorder, specific phobia or selective mutism.ConclusionAvailable guidelines are limited in providing logically explained graded CAM recommendations for anxiety treatment and care. A lack of high-quality evidence and multidisciplinary consultation during the guideline development are two major reasons. High quality and reliable clinical evidence and the engagement of a range of interdisciplinary stakeholders are needed for future CPG development and updating.Systematic review registrationhttps://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42022373694, identifier CRD42022373694.
The pattern of emergency department length of stay in Saudi Arabia: an epidemiological Nationwide analyses of secondary surveillance data
Authors: Alharbi Abdullah A. , Muhayya Mona , Alkhudairy Reem , Alhussain Ahmed A. , Muaddi Mohammed A. , Alqassim Ahmad Y. , AlOmar Reem S. , Alabdulaali Mohammed K. 
Published: December 2023

BackgroundEmergency department length of stay is a vital performance indicator for quality and efficiency in healthcare. This research aimed to evaluate the length of stay patterns in emergency departments across Saudi Arabia and to identify predictors for extended stays. The study used secondary data from the Ministry of Health’s Ada’a program.MethodsUsing a retrospective approach, the study examined data from the Ada’a program on emergency department length of stay from September 2019 to December 2021. These data covered 1,572,296 emergency department visits from all regions of Saudi Arabia. Variables analyzed included quality indicators, year of visit, shift time, hospital type, and data entry method. The analysis was conducted using multiple linear regression.ResultsThe study found that the median length of stay was 61 min, with significant differences among related predictors. All associations were significant with a value of p of less than 0.001. Compared to 2019, the length of stay was notably shorter by 28.5% in 2020 and by 44.2% in 2021. Evening and night shifts had a shorter length of stay by 5.9 and 7.8%, respectively, compared to the morning shift. Length of stay was lower in winter, summer, and fall compared to spring. Patients in levels I and II of the Canadian Triage and Acuity Scales had longer stays than those in level III, with those in level I reaching an increase of 20.5% in length of stay. Clustered hospitals had a longer length of stay compared to the non-clustered ones. Pediatric hospitals had a 15.3% shorter stay compared to general hospitals. Hospitals with data entered automatically had a 14.0% longer length of stay than those entered manually. Patients admitted to the hospital had a considerably longer length of stay, which was 54.7% longer compared to non-admitted patients. Deceased patients had a 20.5% longer length of stay than patients discharged alive.ConclusionData at the national level identified several predictors of prolonged emergency department length of stay in Saudi Arabia, including shift time, season, severity level, and hospital type. These results underline the necessity of continuous monitoring and improvement efforts in emergency departments, in line with policy initiatives aiming to enhance patient outcomes in Saudi Arabia.
How does social integration work when older migrants obtain health services from community? Evidence from national database in China
Authors: Liu Shenshen , Qin Bo , Wang Dongyang 
Published: December 2023

BackgroundThe roles of community are often overlooked when studying the older migrants' health issues, and more importantly, the mediating effect of social integration on the health of older migrants were rarely investigated empirically.MethodsThis study developed comprehensive index to explore this relationship. With data from the 2017 China Migrants Dynamic Survey, the study first examined the potential linkage between community-based health services and the health of older migrants. Ordered logit regressions was carried to investigate whether the self-rated health of older migrants is related to health education and health records provided by community, then the Causal Stepwise Regression and bootstrap method was used to looked into the potential mediation effect.ResultsThe findings showed that older migrants with more community-based health education had higher self-rated health (β = 0.038, SE = 0.009, p &lt; 0.001). However, the community-based health records were not associated with older migrants' health. Moreover, higher levels of social integration were associated with community health education (β = 0.142, SE = 0.014, p &lt; 0.001), and social integration was positively associated with older migrants' health (β = 0.039, SE = 0.002, p = 0.024), indicating the mediation role of social integration.ConclusionThe vital role of community-based health education in improving the health of older migrants was found, and social integration plays a mediating role.
Advanced workstations and collaborative robots: exploiting eye-tracking and cardiac activity indices to unveil senior workers’ mental workload in assembly tasks
Authors: Pluchino Patrik , Pernice Gabriella F. A. , Nenna Federica , Mingardi Michele , Bettelli Alice , Bacchin Davide , Spagnolli Anna , Jacucci Giulio , Ragazzon Andrea , Miglioranzi Leonardo , Pettenon Carlo , Gamberini Luciano 
Published: December 2023

Introduction: As a result of Industry 5.0’s technological advancements, collaborative robots (cobots) have emerged as pivotal enablers for refining manufacturing processes while re-focusing on humans. However, the successful integration of these cutting-edge tools hinges on a better understanding of human factors when interacting with such new technologies, eventually fostering workers’ trust and acceptance and promoting low-fatigue work. This study thus delves into the intricate dynamics of human-cobot interactions by adopting a human-centric view.Methods: With this intent, we targeted senior workers, who often contend with diminishing work capabilities, and we explored the nexus between various human factors and task outcomes during a joint assembly operation with a cobot on an ergonomic workstation. Exploiting a dual-task manipulation to increase the task demand, we measured performance, subjective perceptions, eye-tracking indices and cardiac activity during the task. Firstly, we provided an overview of the senior workers’ perceptions regarding their shared work with the cobot, by measuring technology acceptance, perceived wellbeing, work experience, and the estimated social impact of this technology in the industrial sector. Secondly, we asked whether the considered human factors varied significantly under dual-tasking, thus responding to a higher mental load while working alongside the cobot. Finally, we explored the predictive power of the collected measurements over the number of errors committed at the work task and the participants’ perceived workload.Results: The present findings demonstrated how senior workers exhibited strong acceptance and positive experiences with our advanced workstation and the cobot, even under higher mental strain. Besides, their task performance suffered increased errors and duration during dual-tasking, while the eye behavior partially reflected the increased mental demand. Some interesting outcomes were also gained about the predictive power of some of the collected indices over the number of errors committed at the assembly task, even though the same did not apply to predicting perceived workload levels.Discussion: Overall, the paper discusses possible applications of these results in the 5.0 manufacturing sector, emphasizing the importance of adopting a holistic human-centered approach to understand the human-cobot complex better.
Temperament Characteristics, Anxiety and Depression in People with Familial Mediterranean Fever
Authors: ŞAHİNOĞLU İrem , YILDIRIM ÇETİN Gözde 
Published: December 2023

ABSTRACT
Aim: Familial Mediterranean Fever (FMF) is an autosomal recessive and self-limiting disease. FMF is characterized by recurrent episodes of fever, peritonitis, synovitis and pleuritis. Individuals with chronic illness tend to experience depression or anxiety. It has also been stated that affective temperaments are the basis of mood disorders. The aim of our study is to determine the frequency of anxiety and depression in FMF patients, to determine the dominant temperament type, and to compare the findings with the healthy control group.
Method: 73 patients with FMF and 30 age- and gender-matched healthy individuals without any systemic disease were included in the study. The hospital anxiety and depression scale were used to measure depression and anxiety, and the Temperament Evaluation of Memphis, Pisa, Paris and San Diego –Autoquestionnaire (TEMPS-A) temperament scale was used to determine the temperament type.
Results: The number of cases diagnosed with anxiety was 33 (45.2%) in the patient group and 5 (16.6%) in the control group; The number of cases diagnosed with depression was 23 (31.5%) in the patient group and 2 (6.6%) in the control group, and both were also found to be statistically significantly higher. (P values p=0.02 and p=0.002, respectively)
No statistically significant correlation was found between gender, age, disease duration, regular use of treatment, presence of gene mutation and attack type, and anxiety and depression scores.
According to the TEMPS-A temperament scale, the percentage of patients diagnosed with depressive temperament (20.5%) was higher than the control group (3.3%), and the difference was statistically significant. (p=0.02).
Conclusion: When the clinical picture in FMF patients becomes complicated with anxiety or depression or in the presence of a temperament predisposed to these conditions, there may be various problems in patients' compliance and response to treatment. FMF patients should be monitored for accompanying anxiety or depression during follow-up.
Key Words: Anxiety, Depression, Familial Mediterranean Fever, Temperament
Factores relacionados al éxito anatómico y funcional de la cirugía por desprendimiento de retina regmatógeno. Instituto Regional de Oftalmología “Javier Servat Univazo” (2010 – 2019)
Authors: Quezada-Osoria Marita Lucía , Chirinos-Saldaña Patricia , Adrianzén Rosa 
Published: December 2023

Objetivo: Determinar los factores relacionados al éxito anatómico y funcional de la cirugía por desprendimiento de retina regmatógeno (DRR) en pacientes del Instituto Regional de Oftalmología “Javier Servat Univazo”. Materiales y métodos: estudio observacional en una cohorte retrospectiva de 204 pacientes con DRR sometidos a diferentes técnicas quirúrgicas entre enero 2010-diciembre 2019, con al menos 6 meses de seguimiento. Las variables estudiadas fueron: éxito anatómico (reaplicación primaria de retina) y éxito funcional (mejoría de agudeza visual [AV]); buscándose asociación entre estas variables y las demográficas, clínicas y tiempos de espera. Resultados: La edad promedio fue 50 + 16,5 (9-85) años. Éxito anatómico, se alcanzó en 165 (80,9%) pacientes y funcional en 110 (52,9%). Hubo menor tiempo de espera quirúrgico en pacientes que lograron éxito anatómico (20,0 +/- 22,6 días [1-120]) vs (29,8 +/- 40,1 días [1-210]) (p=0,04) y en los que tuvieron éxito funcional ( 13,3+/- 15,1 [1-100]) vs (31,9 +/- 33,7 [1-210]) (p=0,0002); y menor tiempo de enfermedad y menor tiempo total en los que tuvieron éxito funcional (29,7 +/-56,5 días [1-365] vs (61,9 +/- 110,6 días [1-730]) (p= 0,008) y (43,1 +/-68,1 [5-465]) vs 93,8 +/- 118,3 [3-766]) respectivamente (p=0,0002). Conclusiones: El menor tiempo de espera quirúrgico mostró asociación con el éxito anatómico y funcional de la cirugía por DRR. El menor tiempo de enfermedad y el menor tiempo total mostraron asociación con el éxito funcional. Recomendamos implementar medidas para abreviar tiempos de espera e instaurar una terapia quirúrgica precoz y oportuna en estos pacientes.
Food Habits of Lencam Lethrinus rubrioperculatus Sato, 1978 (Fish: Lethrinidae)
Authors: Tampi Aprillia A. , Bataragoa Nego E. , Rangan Jety K. , Rembet Unstain N. W. J. , Mandagi Stephanus V. , Boneka Farnis B. 
Published: December 2023

This study was conducted to determine the type and composition of food contained in the stomach of the Spotchheek emperor Lethrinus rubrioperculatus in Napo Keluar Nain Likupang waters based on sex and body size. Samples were taken from the catch of fishermen and then the fish samples were then taken to the laboratory for data collection. The method used to determine the composition of fish food used the Index of preponderance (IP). The results showed that the food habits of Spotchheek emperor in Napo Luar Nain Likupang waters with the types of food contained in the stomach of Spotchheek emperor, namely fish, shrimp, gastropods, Polychaeta, crabs (megalopa), and octopus where the main food of Spotchheek emperor is IP fish (94,16%). While the main food based on sex and length of body size is fish, with male IP 96.98% and female 91.15% respectively, while based on body length of Spotchheek emperor where small IP 91.06%, medium IP 98.45% and large IP 82.22%.
Keywords: Food, Likupang, preponderance
Abstrak
Penelitian ini dilakukan untuk mengetahui jenis dan komposisi makanan yang terdapat dalam lambung ikan lencam Lethrinus rubrioperculatus di Napo Keluar Nain Perairan Likupang berdasarkan jenis kelamin dan ukuran tubuh. Sampel diambil dari hasil tangkapan nelayan kemudian sampel ikan selanjutnya dibawah ke Labolatorium untuk pengambilan data. Metode yang digunakan untuk mengetahui komposisi makanan ikan digunakan indeks bagian terbesar (IBT). Metode ini digunakan untuk menilai bermacam-macam jenis makanan ikan.
Hasil penelitian menunjukan bahwa kebiasaan makanan ikan lencam di Napo Keluar Nain Perairan Likupang dengan jenis makanan yang terdapat dalam lambung ikan lencam yaitu ikan, udang, gastropoda, polychaeta, kepiting (megalopa) dan octopus di mana makanan utama dari ikan lencam adalah ikan IBT (94,16%). Sedangkan makanan utama berdasarkan jenis kelamin dan panjang ukuran tubuh yaitu ikan, dengan masing-masing IBT jantan 96,07% dan betina 91,15% sedangkan berdasarkan panjang ukuran tubuh ikan lencam IBT kecil 91,98%, sedang 98,45% dan besar 82,22%.
Kata kunci: Makanan, Likupang, Indeks Bagian Terbesar.