bluuebunny/crossref_metadata_2025_split huggingface dataset:
A continuum of “normal” experience: Positioning mental health struggles as human experiences in the university context
Authors: Wiley Adrianna Nicole 
Published: February 2024

AbstractThis article explores how university students with mental health struggles engage in “illness‐identity” work, the process by which an individual resituates their self in relation to their illness, using a phenomenological approach. Grounded in 24 semi‐structured interviews with Canadian university students between the ages of 18 and 24 years who self‐identify as experiencing mental health struggles, I argue that students do not perform illness‐identity work by making the “I Am” or “I Have” illness identity statements commonly cited in the anthropological literature. Instead, these students focus on the phenomenological content of their struggles making what I call “I Experience” statements. In doing so these students normalize their struggles by understanding them as fluid and ephemeral experiences which exist as a continuum, refuting a construction of mental health struggles as discrete entities objectively present or not in the individual body.
Developing an online knowledge sharing platform and community of practice for health professionals: Experiences from C‐WorKS developed in North East England and Yorkshire during COVID‐19
Authors: van der Graaf Peter , Burrows Andrea , Park Helen , Sowden Sarah 
Published: February 2024

AbstractBackgroundAlthough knowledge sharing online has been recognised as an important strategy for health professionals to apply research findings to their practice, limited research exists on how to develop and implement these platforms to help facilitate collaboration and knowledge sharing.ObjectivesThis study evaluated an online knowledge sharing platform and community of practice developed in the North East of England and Yorkshire during COVID‐19 to support UK health and care professionals to reduce the impact of the wider consequences of COVID‐19.MethodsSemi‐structured interviews with stakeholders (n = 8) and users of C‐WorKS (n = 13), followed by an online survey (n = 19) among a wider group of users to analyse knowledge use.ResultsInterview and survey findings highlighted several strengths, weaknesses, opportunities and threats to support future development of online knowledge sharing platforms.DiscussionOnline knowledge sharing supports six ‘pillars’ of successful research and innovation partnerships. This requires distributed forms of leadership and linking of different knowledge sharing strategies, and careful combination of platforms with communities of practice.ConclusionOnline knowledge sharing provides pragmatic and timely strategies for health professionals in the UK to apply research evidence to their practice. Our study provides generalisable, practical insights in how to develop and implement a knowledge sharing platform.
Real‐world sequential treatment patterns and clinical outcomes among patients with advanced urothelial carcinoma in Japan
Authors: Kita Yuki , Otsuka Hikari , Ito Katsuhiro , Hara Takuto , Shimura Soichiro , Kawahara Takashi , Kato Minoru , Kanamaru Sojun , Inoue Koji , Ito Hiroki , Igarashi Atsushi , Sazuka Tomokazu , Takamatsu Dai , Hashimoto Kohei , Abe Takashige , Naito Sei , Matsui Yoshiyuki , Nishiyama Hiroyuki , Kitamura Hiroshi , Kobayashi Takashi ,   the Japan Urological Oncology Group
Published: February 2024

ObjectivesImmune checkpoint inhibitors and enfortumab vedotin have opened new avenues for sequential treatment strategies for locally advanced/metastatic urothelial carcinoma (la/mUC). In the pre‐enfortumab vedotin era, many patients could not receive third‐line treatment owing to rapid disease progression and poor general status. This study aimed to analyze real‐world sequential treatment practices for la/mUC in Japan, with a focus on patients who do not receive third‐line treatment.MethodsWe analyzed data for 1023 la/mUC patients diagnosed between January 2020 and December 2021 at 54 institutions from a Japanese nationwide cohort.ResultsAt the median follow‐up of 28.5 months, the median overall survival from first‐line initiation for 905 patients who received systemic anticancer treatment was 19.1 months. Among them, 81% and 32% received second‐ and third‐line treatment. Notably, 52% had their treatment terminated before the opportunity for third‐line treatment. Multivariate logistic regression analysis revealed that low performance status (≥1), elevated neutrophil‐to‐lymphocyte ratio (≥3), and low body mass index (<21 kg/m2) at the start of first‐line treatment were independent risk factors for not proceeding to third‐line treatment (p = 0.0024, 0.0069, and 0.0058, respectively). In this cohort, 33% had one of these factors, 36% had two, and 15% had all three.ConclusionsThis study highlights the high frequency of factors associated with poor tolerance to anticancer treatment in la/mUC patients. The findings suggest the need to establish optimal sequential treatment strategies, maximizing efficacy within time and tolerance constraints, while concurrently providing strong supportive care, considering immunological and nutritional aspects.
Best practices for managing malodorous and infected wounds in advanced cervical cancer
Authors: Hamid Habibah Abdul , Lin Xiaoqian , Qin Yuan Kun , Akim Abdah Md , Zhang Longjiu , Wang Jue , Wang Hui , Li Ying , Teng Xiaofei , Zhang Shangmeng , Xu Huanyu , Lin Xiaoqing 
Published: February 2024

AbstractThis cross‐sectional study was conducted to examine the most effective strategies for managing malodorous and infected wounds in patients who have been diagnosed with advanced cervical cancer. The research was conducted in Liupanshui, China. The study specifically examined demographic profiles, wound characteristics and effectiveness of wound management approaches. The study incorporated the heterogeneous sample of 289 participants who fulfilled the inclusion criteria. Data collection was conducted via structured questionnaires and medical record evaluations. Descriptive statistics and statistical analyses, such as regression analysis, were utilized to evaluate demographic attributes, wound profiles and effects of different approaches to wound management. The findings unveiled the heterogeneous demographic composition of patients, encompassing differences in socioeconomic standing, educational attainment and age. A wide range of wound characteristics were observed, as 65.7% of lesions during the acute phase with diameter between 2 and 5 centimetres, while 41.5% of lesions had this range. The most prevalent types of infections were those caused by fungi (48.4%), followed by bacterial infections lacking resistance (38.1%). A moderate degree of odour intensity was prevalent, affecting 45.0% of the cases. With maximal odour reduction of 80%, a mean healing time of 25 days and patient satisfaction rating of 4.5 out of 5, Negative Pressure Wound Therapy demonstrated itself to be the most efficacious treatment method. Additional approaches, such as photodynamic therapy and topical antibiotic therapy, demonstrated significant effectiveness, as evidenced by odour reductions of 70% and 75%, respectively, and patient satisfaction ratings of 4.3 and 4.2. Thus, the study determined challenges associated with management of malodorous and infected lesions among patients with advanced cervical cancer. The results underscored the significance of individualized care approaches, drew attention to efficacious wound management techniques and identified critical determinants that impacted patient recuperation. The findings of this study hold potential for advancing palliative care for individuals diagnosed with advanced cervical cancer.
Renegotiating identity. A Nordic study of adolescent's experiences of living with a parent having heart disease
Authors: Rotvig Camilla , Kikkenborg Berg Selina , Andréasson Frida , Strömberg Anna , Andersen Hege , Norekvål Tone Merete , Bernild Camilla 
Published: February 2024

AbstractAimTo explore adolescents' experiences of having a parent with heart disease.DesignThis qualitative study was performed with semi‐structured individual interviews.MethodsInterviews were conducted with 33 adolescents between 13 and 19 years old, who either had a mother or father with one of these diagnoses: ischemic heart disease, arrhythmia, heart failure, cardiac arrest or heart valve disease. The parent had been ill for at least 6 months and up to 5 years. The study was carried out in Denmark, Norway and Sweden between 2019 and 2022. The analysis was inspired by Reflexive Methodology.ResultsThree central themes emerged: Response to parental heart disease; Growing up ahead of time; and Strategies in a changed life situation. For the adolescents, heart disease was experienced as an acute and lethal disease that put their parents' lives in danger. New routines and roles not only changed everyday life within the family but they also enhanced maturity and appreciation of life. To maintain a balance in life, the adolescents pursued normality and sought a safe space to have a normal youthful life.ConclusionIn a period known to be significant for development, life with parental heart disease appeared as a biographical disruption because adolescents renegotiated their identity to manage their new life situation.ImpactIt is important to help younger family members adapt to parental heart disease by informing them about possible reactions and supporting them in how to adapt to their new life by seeking breaks and normality.Patient or Public ContributionNo patient or public involvement.
How virtual reality, augmented reality and mixed reality facilitate teacher education: A systematic review
Authors: Wang Qin , Li Yanping 
Published: February 2024

AbstractBackgroundVirtual reality (VR), augmented reality (AR) and mixed reality (MR) have sparked recently in improving the effectiveness of teacher education. However, there is a lack of review regarding the utilisation of these technologies in this field. These three technologies, namely VR, AR and MR, can be collectively referred to as extended reality (XR) (as mentioned in reference Tang et al., 2022).ObjectivesRemarkably, the utilisation of XR‐based technologies in teacher education needs to be explored. Moreover, research questions related to the training objectives, methodological features, and the effects of XR‐based teacher education remain unanswered.MethodsTo this end, the present study conducted a systematic review to analyse 52 articles from six databases (including Web of Science, Scopus, IEEE Xplore, ERIC, ScienceDirect, and ACM Digital Library).ResultsThe results indicate that XR technologies have been primarily used to train teachers' procedural knowledge, for instance, classroom management. Furthermore, most studies have primarily focused on pre‐service teachers (PSTs) rather than in‐service teachers and utilised small sample sizes, with VR emerging as the most frequently employed tool. Finally, the majority of the studies reported that XR‐based training affected teachers positively.ConclusionsIt urges researchers and developers to consider theory‐driven training design, which increases the potential to better understand what features of XR promote in‐service teachers' and PSTs' learning and how they do so. This article additionally conducts a SWOT (strengths, weaknesses, opportunities, and threats) analysis of XR‐based teacher education to offer more insightful recommendations and foster further discussion.
Encapsulation of SE‐P47 phage specific to SalmonellaEnteritidis and evaluation of its stability
Authors: Koçer Alaşalvar Gamze , Yıldırım Zeliha 
Published: February 2024

AbstractThis study was conducted to encapsulate the bacteriophage SE‐P47 target to Salmonella Enteritidis by extrusion method and to examine its stability. Screening and optimization of effective factors in the encapsulation process were performed using fractional factorial design and face‐centered central composite design, respectively. The optimum Na‐alginate concentration and the ratio of coating material to phage for the encapsulation of SE‐P47 phage were 1.5% (v/v) and 2:1, respectively. At the optimum encapsulation point, the highest encapsulation efficiency (98.52%), smallest capsule size (1.28 mm), and highest phage titer were achieved. When exposed to heat treatment at 80°C for 30 min, pH 2 and simulated gastric fluid (pH 2.0) for 120 min, the encapsulated phage maintained almost its stability, but the free (non‐encapsulated) phage almost lost its activity. Phage release from beads in simulated intestinal fluid reached 100% in 4 h. In addition, free and encapsulated phage completely maintained their activity for 12 months at 4 and 25°C. The Salmonella phage encapsulated in this study exhibits high stability in harsh conditions. Thus, this encapsulated phage has the potential to be used as a biocontrol agent or therapeutic purposes in the food chain.
Sexual experiences and knowledge of people with moderate intellectual disability
Authors: Estruch‐García V. , Gil‐Llario M. D. , Fernández‐García O. 
Published: February 2024

AbstractBackgroundThis study addresses the sexuality of people with moderate intellectual disabilities (PMID), a topic that has been little studied. Understanding romantic and sexual experiences is highly relevant for reducing stigma and prejudice related to their sexuality. Additionally, comprehending the level of sexual knowledge of PMID contributes to the development of preventive and sexual health education programmes tailored for this group. Our aim is to explore the sexual history (relationships, sexual behaviour, condom use and sexual abuse), sex education received and the level of sexual knowledge of PMID.MethodThe total of 142 PMID completed questionnaires about sexual knowledge and experiences, and their support staff provided additional information. Data were analysed using chi‐square test (χ2) and descriptive statistical analysis.ResultsMasturbation was the most common sexual behaviour (75.7%), especially among men (χ2 = 5.81, P < 0.05). Sexual intercourse was rare, and only 30.5% reported using condoms. Women reported a higher prevalence of self‐reported sexual abuse (27.3% vs. 6% in men). The study also highlighted misconceptions about sexual intercourse risks and contraceptive methods.ConclusionThe results suggest that PMID need sexual education to ensure healthy sexual experiences and prevent risky behaviour.
Defining the relationship between ovarian adult granulosa cell tumors and synchronous endometrial pathology: Does ovarian tumor size correlate with endometrial cancer?
Authors: Tokalioglu Abdurrahman Alp , Oktar Okan , Sahin Mustafa , Ozturk Cagatayhan , Erdogan Ozgur , Yildirim Hande Esra Koca , Ucar Yesim , Kilic Fatih , Ersak Burak , Yalcin Necim , Ozmen Fatma , Alci Aysun , Bas Sevda , Gorgulu Goksen , Selcuk Ilker , Ucar Gokhan , Kocak Ozgur , Cakir Caner , Kilic Cigdem , Comert Gunsu Kimyon , Ureyen Isin , Toptas Tayfun , Narin Mehmet Ali , Tasci Tolga , Taskin Salih , Boran Nurettin , Ozdal Bulent , Sanci Muzaffer , Uncu Dogan , Korkmaz Vakkas , Tekin Ozlem Moraloglu , Ustun Yaprak , Ortac Fırat , Turan Taner 
Published: February 2024

AbstractObjectiveThe main feature of adult granulosa cell tumors (AGCT) is their capacity to secrete hormones, with nearly all of them capable of synthesizing oestradiol. The primary goal of this study is to identify synchronized endometrial pathologies, particularly endometrial cancer, in AGCT patients who had undergone a hysterectomy.Materials and MethodsThe study cohort comprised retrospectively of 316 AGCT patients from 10 tertiary gynecological oncology centers. AGCT surgery consisted of bilateral salpingo‐oophorectomy, hysterectomy, peritoneal cytology, omentectomy, and the excision of any suspicious lesion. The median tumor size value was used to define the relationship between tumor size and endometrial cancer. The relationship between each value and endometrial cancer was evaluated.ResultsEndometrial intraepithelial neoplasia, or hyperplasia with complex atypia, was detected in 7.3% of patients, and endometrial cancer in 3.1% of patients. Age, menopausal status, tumor size, International Federation of Gynecology and Obstetrics stage, ascites, and CA‐125 level were not statistically significant factors to predict endometrial cancer. There was no endometrial cancer under the age of 40, and 97.8% of women diagnosed with endometrial hyperplasia were over the age of 40. During the menopausal period, the endometrial cancer risk was 4.5%. Developing endometrial cancer increased to 12.1% from 3.2% when the size of the tumor was >150 mm in menopausal patients (p = 0.036).ConclusionEndometrial hyperplasia, or cancer, occurs in approximately 30% of AGCT patients. Patients diagnosed with AGCT, especially those older than 40 years, should be evaluated for endometrial pathologies. There may be a relationship between tumor size and endometrial cancer, especially in menopausal patients.
Human resource management technology, workplace performance, and employee well‐being in the British public sector
Authors: Bryson Alex , White Michael 
Published: February 2024

AbstractUsing linked employer–employee data for workplaces in Britain, we find high‐performance workplace practices (HPWPs) are positively associated with public sector workplace performance. Contrastingly, HPWPs are not associated with measures of public sector employees' well‐being or motivation. The implication is that the performance effects of HPWP in the public sector constitute part of efficient management technology, without the need to invoke special employee responses as mediators. Public sector findings differ from those in the private sector: in the latter, HPWPs are positively associated with some performance outcomes but employee outcomes are a complex mix of non‐significant, positive, and negative associations.
Randomized controlled trial to evaluate the rate of successful neonatal endotracheal intubation performed with a stylet versus without a stylet
Authors: Solanki Shailesh , Dogra Shivani , Gupta Pramod K. , Peters Nitin J. , Malik Muneer A. , Mahajan J. K. 
Published: February 2024

AbstractIntroductionNeonates in intensive care units often require endotracheal intubation and mechanical ventilation. During this intubation procedure, a stylet is frequently used along with an endotracheal tube. Despite the widespread use of a stylet, it is still not known whether its use increases the intubation success rate. This study examined the association between stylet use and the intubation success rate in surgical neonates.MethodologyThis single‐center study was conducted between December 2021 and December 2022 in the Neonatal surgical intensive care unit of a tertiary care center in Northern India. Infants were randomized to have the endotracheal intubation procedure performed using either an endotracheal tube alone or with a stylet. The primary outcome of the study was to assess the successful first‐attempt neonatal endotracheal intubation rate with and without using a stylet. Apart from the rate of successful intubation, the duration of the intubation and complications during the intubation procedures as measured by bradycardia, desaturation episodes, and local trauma were also recorded. Both groups were thus compared on above mentioned outcomes.ResultsThe total number of neonates enrolled were 200, and the overall success rate (81% in the stylet group vs. 73% in the non‐stylet group) was not statistically significant. Intubation time was however less, when stylet was used (16.2 ± 4.3 vs. 17.5 ± 5.0 s, p = .046). When the endotracheal tube size was 3 or less, the success rate was substantially higher in the stylet group (80%) than the non‐stylet group (63%), p = .03. No statistical difference was recorded for bleeding and local trauma, though the esophageal intubation rate was higher when intubation was attempted without the stylet.ConclusionEndotracheal intubation using a stylet did not significantly improve the success rate of the procedure, however, intubation time significantly varied between groups and in different conditions. The rigidity and curvature provided by the stylet may facilitate the process of intubation when smaller caliber endotracheal tubes are used.
Ash dieback: From Asia to Europe
Authors: Carroll Dáire , Boa Eric 
Published: February 2024

AbstractAsh dieback is a disease caused by the fungal pathogen Hymenoscyphus fraxineus. Since its emergence in the 1990s, this pandemic disease has spread throughout much of the native range of its host species, the European ash (Fraxinus excelsior). Where present, it can kill up to 85% of ash trees. The loss of these trees has had an enormous impact, particularly in Britain and Ireland where they formed an integral component of wood and farmland, supporting complex communities of other species. Thanks in part to widespread public interest, the ash dieback pandemic has also had a large political impact, leading to changes in the management of plant diseases. Now, three decades after the emergence of the disease, ambitious projects to breed tolerant plants, and evidence of natural selection for resistance, give hope for the recovery of European ash. The aim of this review is to provide an overview of the history of the ash dieback pandemic, from its emergence to current efforts to mitigate its effects. We discuss the emergence of ash dieback and the wide body of research that has led to our current understanding of the disease. We question which aspects of the disease have led to it holding a particular interest to the public. With a focus on the islands of Britain and Ireland, we discuss how this has driven changes in the management of plant diseases, which may give hope for the control of emerging pathogens in the future.
Avoiding the blame game: NGOs and government narrative strategies in landscape fire policy debates in Russia
Authors: Chalaya Tatiana , Uldanov Artem 
Published: February 2024

AbstractTo what extent can nongovernmental organizations (NGOs) communicate policy problems in an authoritarian country, and how limited are they in narrating policy alternatives? This article seeks to develop studies on the application of the Narrative Policy Framework (NPF) in Russia, extend our knowledge about the use of narrative strategies in centralized and authoritarian policy processes, highlight certain methodological peculiarities related to the devil–angel shift calculation, and test causal mechanism hypotheses that have not previously been applied to the analysis of policy debates in Russia. The study examines hypotheses based on the narrative strategies (devil–angel shift, scope of conflict, and causal mechanisms) that were used by government and NGO coalitions in the debate about “landscape fire” policies in Russia over the period 2019–2021. The results show that the differences between the coalition's narrative strategies were not as significant as had been shown previously. The government coalition uses a strong angel shift in its narratives and avoids conflict expansion. The NGO coalition demonstrates a moderate angel shift, but with the use of conflict expansion in parts of the narratives. Both coalitions use the intentional or inadvertent causal mechanism blaming the citizens for starting the fires, but differ in employing causal mechanisms when discussing the large scale of landscape fires.