bluuebunny/crossref_metadata_2025_split huggingface dataset:
Expanding the known distribution of phascolartid gammaherpesvirus 1 in koalas to populations across Queensland and New South Wales
Authors: Wright Belinda R. , Casteriano Andrea , Muir Yasmine S. S. , Hulse Lyndal , Simpson Sarah J. , Legione Alistair R. , Vaz Paola K. , Devlin Joanne M. , Krockenberger Mark B. , Higgins Damien P. 
Published: January 2024

AbstractKoala populations across the east coast of Australia are under threat of extinction with little known about the presence or distribution of a potential pathogen, phascolartid gammaherpesvirus 1 (PhaHV-1) across these threatened populations. Co-infections with PhaHV-1 and Chlamydia pecorum may be common and there is currently a limited understanding of the impact of these co-infections on koala health. To address these knowledge gaps, archived clinical and field-collected koala samples were examined by quantitative polymerase chain reaction to determine the distribution of PhaHV-1 in previously untested populations across New South Wales and Queensland. We detected PhaHV-1 in all regions surveyed with differences in detection rate between clinical samples from rescued koalas (26%) and field-collected samples from free-living koalas (8%). This may reflect increased viral shedding in koalas that have been admitted into care. We have corroborated previous work indicating greater detection of PhaHV-1 with increasing age in koalas and an association between PhaHV-1 and C. pecorum detection. Our work highlights the need for continued surveillance of PhaHV-1 in koala populations to inform management interventions, and targeted research to understand the pathogenesis of PhaHV-1 and determine the impact of infection and co-infection with C. pecorum.
A randomized controlled trial comparing different sites of high-velocity low amplitude thrust on sensorimotor integration parameters
Authors: Niazi Imran Khan , Navid Muhammad Samran , Merkle Christopher , Amjad Imran , Kumari Nitika , Trager Robert J. , Holt Kelly , Haavik Heidi 
Published: January 2024

AbstractIncreasing evidence suggests that a high-velocity, low-amplitude (HVLA) thrust directed at a dysfunctional vertebral segment in people with subclinical spinal pain alters various neurophysiological measures, including somatosensory evoked potentials (SEPs). We hypothesized that an HVLA thrust applied to a clinician chosen vertebral segment based on clinical indicators of vertebral dysfunction, in short, segment considered as “relevant” would significantly reduce the N30 amplitude compared to an HVLA thrust applied to a predetermined vertebral segment not based on clinical indicators of vertebral dysfunction or segment considered as “non-relevant”. In this double-blinded, active-controlled, parallel-design study, 96 adults with recurrent mild neck pain, ache, or stiffness were randomly allocated to receiving a single thrust directed at either a segment considered as “relevant” or a segment considered as “non-relevant" in their upper cervical spine. SEPs of median nerve stimulation were recorded before and immediately after a single HVLA application delivered using an adjusting instrument (Activator). A linear mixed model was used to assess changes in the N30 amplitude. A significant interaction between the site of thrust delivery and session was found (F1,840 = 9.89, p < 0.002). Pairwise comparisons showed a significant immediate decrease in the N30 complex amplitude after the application of HVLA thrust to a segment considered “relevant” (− 16.76 ± 28.32%, p = 0.005). In contrast, no significant change was observed in the group that received HVLA thrust over a segment considered “non-relevant” (p = 0.757). Cervical HVLA thrust applied to the segment considered as “relevant” altered sensorimotor parameters, while cervical HVLA thrust over the segment considered as “non-relevant” did not. This finding supports the hypothesis that spinal site targeting of HVLA interventions is important when measuring neurophysiological responses. Further studies are needed to explore the potential clinical relevance of these findings.
Assessing urban park equity in Chaoyang District, Beijing using online review data
Authors: Zou Ning , Mi Xiayuan , Xiao Yang , Li Yunyuan , Hu Nan 
Published: January 2024

AbstractUrban parks are essential components of urban ecosystems, providing vital ecological resources for city residents. However, the rapid expansion of high-density urban areas has led to an unequal distribution of park resources, raising growing concerns about spatial equity. To address these challenges, we employed an improved Gaussian two-step floating catchment area (2SFCA) method, considering park quality variations and integrating sentiment scores from park reviews to calculate a comprehensive park accessibility index, accounting for both supply and demand dynamics among park users. The results demonstrate the significance of park management, as users prioritise convenience and cleanliness of public facilities. Recreational quality significantly influences park distribution equity, with areas near Beijing’s initial greenbelt zone showing improved accessibility (IA). Nonetheless, our analysis exposes disparities in urban park resource allocation within the Chaoyang District, indicating relative inequity. Spatial supply and demand mismatches, especially in the northwest and southeast, are evident. To enhance park layout equity, we recommend strategies like identifying and repurposing underused spaces, establishing pocket parks and micro-green areas, and improving recreational facilities. It is crucial to address the needs of vulnerable groups such as older residents and children. These insights stress the importance of ensuring fair urban park access to enhance the well-being of all city residents.
Synthesis and characterization of iron oxide-commercial activated carbon nanocomposite for removal of hexavalent chromium (Cr6+) ions and Mordant Violet 40 (MV40) dye
Authors: Mohamed Soha Mahrous Ismail , Yılmaz Murat , Güner Eda Keleş , El Nemr Ahmed 
Published: January 2024

AbstractIron Oxide-commercial activated carbon nanocomposite (CAC-IO) was prepared from commercial activated carbon (CAC) by the co-precipitation method, and the resulting nanocomposite was used as an adsorbent to remove hexavalent chromium (Cr6+) ions and Mordant Violet 40 (MV40) dye from wastewater. The produced materials (CAC, CAC after oxidation, and CAC-IO) were comparatively characterized using FTIR, BET, SEM, EDX TEM, VSM, and XRD techniques. The adsorption mechanism of Cr6+ ions and MV40 dye on CAC-IO was examined using Langmuir and Freundlich isotherm models.. Different models were applied to know the adsorption mechanism and it was obtained that Pseudo-second order fits the experimental data better. This means that the adsorption of the adsorbate on the nanocomposite was chemisorption. The maximum removal percent of Cr6+ ions by CAC-IO nanocomposite was 98.6% determined as 2 g L–1 adsorbent concentration, 100 mg L–1 initial pollutant concentration, solution pH = 1.6, the contact time was 3 h and the temperature was room temperature. The maximum removal percentage of Mordant Violet 40 dye (C.I. 14,745) from its solutions by CAC-IO nanocomposite was 99.92% in 100 mg L–1 of initial dye concentrations, 1.0 g L–1 of adsorbent concentration, solution pH = 2.07, the contact time was 3 h. The MV40 dye adsorption on CAC-IO was the most fitted to the Freundlich isotherm model. The maximum adsorption capacity was calculated according to the Langmuir model as 833.3 mg g–1 at 2 g L–1 of adsorbent concentration and 400 mg L–1 of initial MV40 dye concentration. The Cr6+ ions adsorption on CAC-IO was more fitted to the Freundlich model with Qmax, equal to 312.50 mg g–1 at 1 g L–1 adsorbent concentration and 400 mg L–1 of Cr6+ ions initial concentrations.
Changes in sensitivity and hedonic rating to transcutaneous electrical nerve stimulation following COVID-19
Authors: Błażejewski Grzegorz , Witkoś Joanna , Hartman-Petrycka Magdalena 
Published: January 2024

AbstractCOVID-19 affects not only the respiratory system but also other biological systems such as the nervous system. Usually, these changes are reported based on the patient's subjective description. The aim of our study, therefore, was to objectively determine the effect that the SARS-CoV-2 virus and COVID-19 disease has on sensory threshold and the hedonic and subjective perception of an electrical stimulus. The sensory threshold was tested on the inner forearm by applying non-invasive transcutaneous electrical nerve stimulation (TENS) with 100 Hz and 100 µs parameters and a biphasic current waveform. The study involved 211 participants, aged 22–79 years, with a mean age of 56.9 ± 12.1 years. There were 131 subjects in the COVID group, while the NON-COVID group, the control group, was matched to the COVID group in terms of gender, age, body mass index and presence of chronic diseases. The research was carried out in 2022. Sensory sensitivity was highest in the group that had suffered with COVID-19. The median sensory sensitivity was 11 mA in the COVID group and 14 mA (p < 0.001) in the NON-COVID group, however, the current sensitivity threshold decreased over time (R = 0.52, p < 0.001). Post COVID-19, the electrical stimulus was more often perceived as unpleasant: COVID versus NON-COVID (23% vs. 3%, p < 0.001) and as a different sensation to tingling (27% vs. 2%, p < 0.001). Post-COVID-19 patients have a lower sensory threshold, the electrical stimulus is more often described as unpleasant and in subjective feelings it is more often described as pinching. The differences between COVID and NON-COVID decrease with time since the onset of COVID symptoms.
The role of the GABAergic cells of the median raphe region in reinforcement-based learning
Authors: Chaves Tiago , Török Bibiána , Fazekas Csilla , Correia Pedro , Karailiev Peter , Oravcova Henrieta , Sipos Eszter , Biró László , Haller József , Jezova Daniela , Zelena Dóra 
Published: January 2024

AbstractLearning and memory are important in everyday life as well as in pathological conditions. The median raphe region (MRR) contributes to memory formation; however, its precise role and the neurotransmitters involved have yet to be elucidated. To address this issue, we stimulated the MRR neurons of mice by chemogenetic technique and studied them in the operant conditioning and active avoidance tests. The virus carrier infected a variety of neuron types including both GABAergic and glutamatergic ones. Behavior was not influenced by stimulation. We hypothesize that the lack of effect was due to opposing effects exerted via GABAergic and glutamatergic neurons. Therefore, next we used VGAT-Cre mice that allowed the specific manipulation of MRR-GABAergic neurons. The stimulation did not affect behavior in the learning phase of the operant conditioning task, but increased reward preference and total responses when operant contingencies were reversed. The enhanced responsiveness might be a proclivity to impulsive behavior. Stimulation facilitated learning in the active avoidance test but did not affect reversal learning in this paradigm. Our findings suggest that MRR-GABAergic neurons are involved in both learning and reversal learning, but the type of learning that is affected depends on the task.
Optimal power flow and computer‐based analysis of a simultaneous AC–DC power transmission system
Authors: Quayyoom Layeba , Rahman Obaidur , Bakhsh Farhad Ilahi , Ahmad Akbar 
Published: January 2024

AbstractElectricity demand is constantly increasing with the growing population, and the process of establishing new transmission lines has become complicated due to the rise in industrialization and urbanization. One solution to meeting this increased demand is to improve the power transfer capability by increasing the transmission voltage. However, the existing transmission lines may not be able to handle the increased load if they are pushed to their thermal limit. This paper presents a mathematical analysis of a simultaneous AC–DC transmission system transmitting power at different values of parameters. The computational analysis is carried out using MATLAB, and the circuit model simulation is validated by using power systems computer aided design (PSCAD/EMTDC). The transmitted power is evaluated by varying the transmission angle and transmission length for a fixed voltage, and then by varying the transmission angle and voltage for a fixed transmission length. Both these cases are analyzed using approximate and actual formulas. The results of the computation and simulation show close conformity.
THEMIS 2.0: A self-consistent model for dust extinction, emission, and polarisation
Authors: Ysard N. , Jones A. P. , Guillet V. , Demyk K. , Decleir M. , Verstraete L. , Choubani I. , Miville-Deschênes M.-A. , Fanciullo L. 
Published: January 2024

Context. Recent observational constraints in emission, extinction, and polarisation have at least partially invalidated most of the astronomical standard grain models for the diffuse interstellar medium. Moreover, laboratory measurements on interstellar silicate analogues have shown quite significant differences with the optical properties used in these standard models.
Aims. To address these issues, our objective is twofold: (i) to update the optical properties of silicates and (ii) to develop The Heterogeneous dust Evolution Model for Interstellar Solids (THEMIS) to allow the calculation of polarised extinction and emission.
Methods. Based on optical constants measured in the laboratory from 5 µm to 1 mm for amorphous silicates and on observational constraints in mid-IR extinction and X-ray scattering, we defined new optical constants for the THEMIS silicates. Absorption and scattering efficiencies for spheroidal grains using these properties were subsequently derived with the discrete dipole approximation.
Results. These new optical properties make it possible to explain the dust emission and extinction, both total and polarised. It is noteworthy that the model is not yet pushed to its limits since it does not require the perfect alignment of all grains to explain the observations and it therefore has the potential to accommodate the highest polarisation levels inferred from extinction measurements. Moreover, the dispersion of the optical properties of the different silicates measured in the laboratory naturally explain the variations in both the total and polarised emission and extinction observed in the diffuse interstellar medium.
Conclusions. A single, invariant model calibrated on one single set of observations is obsolete for explaining contemporary observations. We are proposing a completely flexible dust model based entirely on laboratory measurements that has the potential to make major advances in understanding the exact nature of interstellar grains and how they evolve as a function of their radiative and dynamic environment. Even if challenging, this is also relevant for future cosmic microwave background (CMB) missions that will aim to perform precise measurements of the CMB spectral distortions and polarisation.
Displaying a negative stance by questioning meaning
Authors: De Stefani Elwys 
Published: January 2024

Abstract
Speakers of Italian have at their disposal a variety of phrasal and clausal resources for questioning meaning,
among which is the format che cosa vuol dire X? (‘what does X mean?’). Likewise, recent studies on English and
German about similar resources have shown that speakers use them to identify a meaning problem. This contribution takes a step
further, by showing that the ‘what does X mean?’ format allows speakers to accomplish a variety of actions. These may be related
to (a) the negotiation of understanding, and (b) the display of a negative stance. In many occurrences, the interactants display
clear orientation to either a problem of understanding or a commonly shared negative stance. However, in sensitive environments
(such as conflictual discussions), the resource allows speakers to (c) frame their negative stance as a problem of understanding,
thereby resisting escalation of the conflict. The ‘what does X mean?’ format may or may not be produced with concomitant embodied
behaviour. When the format is used to problematise understanding, no specific embodied conduct is observed. Yet, when it is used
to display a negative stance, speakers may be seen to perform the grappolo gesture.
Multilevel dimension-independent likelihood-informed MCMC for large-scale inverse problems
Authors: Cui Tiangang , Detommaso Gianluca , Scheichl Robert 
Published: January 2024

Abstract
We present a non-trivial integration of dimension-independent likelihood-informed (DILI) MCMC (Cui et al 2016) and the multilevel MCMC (Dodwell et al 2015) to explore the hierarchy of posterior distributions. This integration offers several advantages: First, DILI-MCMC employs an intrinsic likelihood-informed subspace (LIS) (Cui et al 2014)—which involves a number of forward and adjoint model simulations—to design accelerated operator-weighted proposals. By exploiting the multilevel structure of the discretised parameters and discretised forward models, we design a Rayleigh–Ritz procedure to significantly reduce the computational effort in building the LIS and operating with DILI proposals. Second, the resulting DILI-MCMC can drastically improve the sampling efficiency of MCMC at each level, and hence reduce the integration error of the multilevel algorithm for fixed CPU time. Numerical results confirm the improved computational efficiency of the multilevel DILI approach.
A penetration efficiency model for the optimization of solid conical microneedles’ geometry
Authors: Piccolo Leonardo , Bornillo Kristal , Micheli Sara , Sorgato Marco , Ricotta Mauro , Cimetta Elisa , Lucchetta Giovanni 
Published: January 2024

Abstract
Microneedles (MNs) are promising alternatives to pills and traditional needles as drug delivery systems due to their fast, localized, and relatively less painful administration. Filling a knowledge gap, this study investigated and optimized the most influential geometrical factors determining the penetration efficiency of MNs. The effects of height, base diameter, and tip diameter were analyzed using the finite element method, with results showing that the most influencing factor was base diameter, followed by height. Moreover, the taper angle, which is dependent on all the geometrical factors, was found to directly affect the penetration efficiency at a fixed height. An additional model was developed to relate the height and taper angle to penetration efficiency, and the results were experimentally validated by compression testing of MN array prototypes printed using two-photon photolithography. The numerical model closely predicted the experimental results, with a root mean square error of 9.35. The results of our study have the potential to aid the design of high-penetration efficiency MNs for better functionality and applicability.
Wideband directional-fed holographic metasurface with integrated monopole and parabolic reflector for far-/near-field beams manipulations
Authors: Xue Song , Shen Yizhu , Xu Ziyu , Zhang Yi , Hu Sanming 
Published: January 2024

Abstract
Holographic metasurface has been widely investigated, but suffers from the trade-off between bandwidth, gain, and integration. In this article, a wideband high-gain holographic metasurface with miniaturized integrated monopole is proposed. It employs the geometrical characteristics of parabolic reflector to realize directional-fed metasurface, and the footprint is reduced to only one-third of the conventional center-fed designs. By varying modulation index and paraboloid height, the bandwidth and gain are improved simultaneously. To validate the proposed idea, two prototypes are analyzed and fabricated to demonstrate flexible beam manipulation in respective far-field radiation and near-field propagation. Pencil beam pays more attention to the far-field and directionality of the beam, while Bessel beam focuses more on the near-field and non-diffractive of the beam. In both cases, the measured results are well-matched with the simulation. The proposed holographic metasurface for far-field applications features wide bandwidth, high gain, and planar integration simultaneously. Moreover, to the best of the authors’ knowledge, this is the first Bessel beam generator using directional-fed holographic metasurface with parabolic reflector.
Kirigami-inspired self-powered pressure sensor based on shape fixation treatment in IPMC material
Authors: Low Jen-Hahn , Chee Pei-Song , Lim Eng-Hock , Ganesan Vinod 
Published: January 2024

Abstract
Rapid advances in sensing technologies have brought about the fast development of wearable electronics for biomedical applications. Since its conception, over the years, the ionic polymer metal composite (IPMC) is a new man-made material that has demonstrated its great potential for wearable devices due to self-powered sensing capabilities. Here, for the first time, a novel Kirigami technique with unique cut patterns has been employed for designing a stretchable IPMC sensor with enhanced performance. As Nafion itself exhibits the characteristic of shape memory polymer, the Kirigami structure that is built using the IPMC can be buckled up by loading and heating the IPMC above the deformation temperature, T
def. To further enhance the memory effect, the Kirigami structure has further been locked by immersing it in potassium hydroxide for the formation of deprotonated Nafion. The voltage output of the proposed IPMC with Kirigami shows a superior performance with 3 times improvement over the conventionally planar electrodes. Dynamic tests with a range of displacements have been performed to validate the sensor design and the robustness of the Kirigami structure. This novel Kirigami-based IPMC sensor has been successfully demonstrated for braille sensing by designing 7 independent electrodes.
Electrohydrodynamic peristaltic microfluidic flow with thermal and molecular analysis featuring sloped configurations
Authors: Noreen Saima , Aslam Farida 
Published: January 2024

Abstract
This study examines the simultaneous impacts of thermal and molecular transfer of non-Newtonian fluid propelled by the collective impact of electroosmosis and peristaltic pumping via inclined channel. Internal frictional heating and heat generation are also taken into consideration. The electrohydrodynamic phenomenon is described by the nonlinear Poisson–Boltzmann equation. The problem is modulated mathematically through a system of coupled non-linear differential equations in wave frame of reference. Using the regular perturbation method around a small wave number δ, we obtain sequential solutions for stream function ψ, electric potential ϕ, velocity

u
,

pressure gradient

dp

dx

,

temperature θ and concentration Ω distributions. The influences of newly arising parameters such as the electroosmotic parameter

m

e

,

relaxation time parameter

λ

1

,

retardation time parameter

λ

2

,

wave number δ, Reynold’s number

Re
,

heat generation parameter β, Prandtl number

Pr
,

Schmidt number

Sc
,

Froude number

Fr

and Soret number

Sr

on physical characteristics are analyzed graphically. There is an inverse correlation between the parameters of relaxation time and retardation time and their effects on axial velocity, concentration, and temperature distributions. In particular, the temperature of the fluid increases as the EDL parameter, relaxation time parameter, viscous dissipation parameter, and Reynolds number increase, but decreases as the retardation time parameter increases. Moreover, the axial pressure gradient increases as Reynolds number and inclination angle increase, while it decreases as Froude number increases. The current model has applicability in the chemical industry, reservoir engineering, micro-fabrication, and biomedical applications, where electroosmotic effects on heat and mass movement are crucial.