bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Impact of the Travel and Tourism Sector on the Growth of the National Economy
Authors: QAMARI Ika Nurul , SHAIKH Mohsin , GARAD Askar , SURYONO Leli Joko , NURYAKIN Nuryakin 
Published: October 2023

Purpose – This study aimed to examine the interrelationship between the economic development of the country and the development of tourism. This study strived to conceptually categories in TandT sectors recent reports in India and Indonesia. Methodology – This study employed secondary data involving United Nations (UN) and International Monetary Fund (IMF) reports and highly-rated peer-reviewed scientific journal articles. Systematic deductive reasoning was employed to perform UN and IMF report reviews. Findings– The service sector's contribution to the Gross Domestic Product (GDP) is denoted as a progress predictor. Therefore, organizations are required to adapt tactics and operations in SCs to address current dynamic settings, possibilities, and threats. An essential procedural element involved adequate partner choice in SC to organize and provide competitive package tours. High service sector contribution to the national economy implied industrial advancement. As developing nations, Indonesia and India encompass rapidly advancing service industries on a global scale. Economically, the travel and tourism (TandT) sector proved essential in facilitating GDP and employment opportunities while a competent workforce vitally affected industrial growth and development. In this vein, human resource development is a crucial industrial component. Research limitation/implications – This paper provides several important points that need further research in the future. Some points have been presented regarding the Integration of technological engines and important factors of basic engines in tourism. Originality/value– This study shows the interrelationship between the economic development of the country and the development of tourism. Tourism helps in revitalizing the supply chain sector, which directly affects economic and industrial development and vice versa. This is beneficial for both governments and those in the tourism and economic sectors to make joint and effective cooperation. This research also mentions many important points that may help them to revitalize this relationship.
Exploring Factors Shaping Tourist Satisfaction: A Case Study of the Chefchaouen Destination in Morocco
Authors: EL KHADAR Mariame 
Published: October 2023

This study aims to identify determinants of tourist satisfaction in Chefchaouen, an authentic destination in the north-eastern of Morocco. Our study identifies factors that contribute more to tourists’ satisfaction and comes up with recommendations.
Methodologically, an extended bibliographical review is presented to establish the hypotheses and the research conceptual model. A deductive approach is suitable for this study. It is a quantitative study based on a survey filled out by tourists on a visit to produce results.
The results of our study show that two dimensions ‘joy’ and ‘positive surprise’ have a direct and positive influence on tourist satisfaction. the results also show that staying in Chefchaouen gives them joy, pleasure, a sense of wonder, inspiration, and amazement. Generally, this destination provides them with pleasant and surprising experiences.
Our study also has some limitations due to the small size of our sample and its composition. It neglects domestic tourists All these limitations constitute new research perspectives in marketing tourist destinations. This research is original because it reveals to Chefchaouen and other destination marketing managers, the importance of emotional dimensions in evaluating the destination tourist experience.
Temporal Change of Foreign Tourism in Sri Lanka: A Study on Economic Perspective
Authors: BHAKAT Ayan , DAS Nirmalya , GUCHHAIT Santu 
Published: October 2023

Purpose: Many countries rely heavily on tourism as an economic driver. It has a large workforce. Sri Lanka's economic turmoil has been a big impediment to tourist trips. Tourists are keeping away from this picturesque country because of high inflation, frequent power outages, and fuel scarcity. This impacted the tourism industry, job losses etc. This research investigates the relationship between foreign tourist arrivals (FTA) and nation's GDP, and the barriers to tourism growth.
Methodology: The work is completed through gaining access to quantitative and qualitative data. SLTDA tourist reports from 2018 to 2022, World Data (2020), UNWTO (2017), Central Bank of Sri Lanka provided quantitative data. The information comes from an assessment of literature, articles published in significant newspapers, journals. Cartographic techniques were employed for analysis, and the correlation test was used to assess the relationship between tourist arrivals, foreign receipts, and GNP.
Findings: There is a positive relationship between FTA and tourism growth. Economic crisis has deteriorated Sri Lanka’s tourism as people are unwilling to visit Sri Lanka owing to uncertainty, inflation, power outages, and fuel scarcity, even the domestic tourist are unwilling to spend money for travelling and leisure purpose.
Originality: In addition to demand and supply factors, the article indicates that other factors, like inflation and currency value, play a significant role in tourism development. The paper cites several reasons why developing-country governments must preserve stability in order to thrive all sectors of the country's economy, including tourism.
Exosomal prognostic biomarkers predict metastatic progression and survival in breast cancer patients
Authors: Ceran Serdar Ceyhan , Osmanlıoğlu Şeyma 
Published: October 2023

Abstract

Objectives
This study aims to comprehensively evaluate extracellular vesicle (EV)-based biomarkers circulating in body fluids with significant prognostic value in breast cancer (BrCa).

Methods
We systematically searched WOS, PubMed, and Scopus databases on 14 February 2023 for studies indicating overall survival(OS), progression/disease/event-free survival(PFS/DFS/EFS), and metastatic progression. We computed univariate(UHR) or multivariate adjusted(AHR) hazard ratios, and AUC values for all prognostic EV-based biomarkers of blood-origin using random effect model and Stata 16.0 software. Subgroup analysis was conducted for positive and negative prognostic factors.

Results
Twenty-one articles comprising twenty-six studies and 3,423 patients satisfied the inclusion criteria. EV-based negative biomarkers indicated low OS(UHR=2.31, CI=1.77–3.03, I2=60.12 %, p<0.001); worse DFS/PFS/EFS(UHR=3.91, CI=2.82–5.43, I2=19.08 %, p=0.24); increased risk for metastasis(pooled AUC=0.91). Out of 56 EV-based biomarkers that have been previously described, we identified PD-L2, sHLA-G, exo-XIST, and miR4800 as the best predictors of OS of BrCa patients. Expression levels of miR155, Annexin-A2, sHLA-G, PD-L2, miR1246, PSMA and the biomarkers constructing the EVP-panel hold significant potential to be combined in a prognostic-panel predicting DFS/PFS/EFS of BrCa patients. PD-L2 and sHLA-G standing out as leading biomarkers in both OS and DFS highlights the importance of immune system evasion for patient survival. In addition, we suggest that reinforcement with additional RNA biomarkers could significantly increase the metastatic prediction power of the previously described EVDX-panel.

Conclusions
This meta-analysis provides an overview of the liquid biopsy-based EV-biomarkers associated with OS, DFS, and metastatic progression of BrCa for the first time. Prognostic efficiency of the proposed panels should be further investigated before transition to clinical use.
Crystal structure and electrochemical hydrogenation of HoNiIn1-xAlx (x = 0-1) solid solution
Authors: Nychyporuk G. , Kordan V. , Horiacha M. , Halyatovskii B. , Hudzo O. , Zaremba V. , Pavlyuk V. 
Published: October 2023

The influence of the substitution of indium by aluminum in HoNiIn compound at 873 K was investigated in the full concentration range by means of powder X-ray diffraction and EDX analysis. The formation of continuous solid solution was determined and changes of the unit cell parameters were calculated: HoNiIn1.0–0Al0–1.0 (ZrNiAl-type structure, space group P-62m, a = 0.74343(4)–0.69959(6) nm and c = 0.37472(3)–0.38289(4) nm, V = 0.17936(2)–0.16229(3) mn3). The best discharge capacity after electrochemical hydrogenation studies of HoNiIn1-xAlx solid solution is observed for battery prototypes with HoNiIn0.2Al0.8- and HoNiIn0.4Al0.6-based electrodes.
RESPOSTA MORFOLÓGICA DO CORAÇÃO DE ZEBRAFISH (Danio rerio) DECORRENTES DE DIETA HIPERCALÓRICA E EXERCÍCIO FÍSICO
Authors: MENDES G. P. , SILVA P. H. S. , GONÇALVES P. V. P. , SANTOS C. R. , LIMA E. M. M. , BARRETO-VIANNA A. R. C. 
Published: October 2023

Foi avaliada quantitativamente a estrutura dos cardiomiócitos, núcleos de cardiomiócitos e fibras colágenas cardíacas de 48 Zebrafish, adultos, submetidos a dieta hipercalórica e exercício físico. A densidade volumétrica (Vv%) de cardiomiócitos foi de 54,71% ± 5,42 no GM-dieta manutenção e de 44,31% ± 6,21 no GMex dieta manutenção + exercício físico, P=0,0142; de 62,71% ± 7,4 no GH-dieta hipercalórica e de 65,21% ± 2,29 no GHex-dieta hipercalórica e exercício físico, P=0,028. A densidade volumétrica (Vv%) de núcleos de cardiomiócitos foi de 18,29% ± 5,28 no GM e de 16,71% ± 1,25 no GMex, P=0,5384; de 16,14% ± 5,69 no GH e de 14,14% ± 1,21 para os animais do GHex, P=0,3738. A densidade volumétrica (Vv%) das fibras colágenas foi de 7% ± 0,86 no GM e de 4,89% ± 2,14 no GMex, P=0,0391; de 4% ± 1,73 no GH e de 3,33% ± 2,23 no GHex, P=0,0412. A estrutura cardíaca sofreu modificações estruturais das células musculares e ainda nas quantidades de tecido conjuntivo. Comprovando desta forma a efetividade do modelo utilizado e protocolo imposto.
Morphological and Anatomical Study of Some Species of Ziziphus L. (Rhamnaceae) Growing in Iraq
Authors: AL-Hadeethi Muazaz A. Hasan , Al-shami Sinan S. Dheyab , AL-Taie Ali T. , Hashim Rasha Tareq 
Published: October 2023

The genus Ziziphus is one of the Family Rhamnaceae and consists of more than 170 species distributed in tropical and subtropical regions. All the species in the genus are of economical and medical importance. This study was conducted to identify the morphologically and anatomically features of the genus in Iraq. The field survey was conducted across the study area where 4 species (Ziziphus jujube, Z. mauritiana, Z. nummularia and Z. spina-christi) were collected and used in the study. The result showed that there is variation in morphological and anatomical features among the species in the stem cross-section and longitudinal section of leaves also the differences appeared in the epidermis of leaves.
A Non-Randomized Single-Blind Clinical Study to Assess the Utility of Strychnos Nux-Vomica L. in the Management of Patients with Bowel Disorders
Authors: . Shruti , Dolas Vaishali V. 
Published: October 2023

Purpose: Bowel disorders encompass a cluster of gastrointestinal conditions marked by persistent symptoms like abdominal discomfort, bloating, and changes in bowel patterns. They represent a significant public health concern necessitating increased awareness, diagnosis, and treatment efforts. This research sought to explore the potential of Nux Vomica as a treatment option for individuals suffering from bowel disorders, with the goal of reducing the frequency and intensity of their symptoms to provide optimal relief. Materials and Methods: This research involved 30 individuals diagnosed with bowel disorders according to the Rome IV diagnostic criteria. They received treatment with the homoeopathic remedy Nux Vomica, selected based on a comprehensive assessment of their symptoms. To assess the treatment's effectiveness, the study monitored a reduction in the number of symptoms and quantified improvements using the Gastrointestinal Quality of Life Index questionnaire. Results: Statistical analysis was carried out using the Student paired "t" test. Following the therapy, a significant reduction in the number of symptoms was observed, and no adverse effects were documented. On average, the GIQLI score exhibited an improvement of -38.23 ± 13.68 points (t-statistic value: 15.31), while the average decrease in the number of symptoms amounted to 4.03 ± 1.47 points (t-statistic value: 14.99). The resulting "p" value was 0.000, indicating an exceptionally low level of significance upon completion of the study. Conclusion: The homoeopathic remedy Nux Vomica effectively addresses bowel disorders. These results open up new avenues for future research exploring the treatment of bowel disorders with homeopathic medicine.
Actual Status of Law Application on Land Acquisition for Socio-Economic Development Purposes
Authors: Son Cao Thanh 
Published: October 2023

Vietnamese law has regulations on land acquisition cases for socio-economic development for national and public benefits, limiting land acquisition cases according to the scale of each type of project that will be approved and deciding the investment and investment policy. However, certain realities still exist. Analysis and comparison are the main methods used in the study. The article aims to present the current situation and recommend improving the land acquisition law for socio-economic development.
Comparative Study of Physico- chemical Parameters of Ground water of Residential and Industrial area of Sirgitti in Bilaspur District
Authors: Patel Rajani , Nayar Renu , Patel Kavita , Tandon Sandeep Kumar 
Published: October 2023

Water is available in abundance on the earth. It is one of the main reasons which make life possible on our planet. The quality strength and type of sewage depends upon the human population, industrialization, deforestation and life style of people. Analytical explorations of some selected physico- chemical parameter have been made on the ground water bodies of Sirgitti industrial area. In the present comparative study for physico-chemical analysis water samples were collected from to different locations the residential and industrial area of Sirgitti in Bilaspur district. The laboratory test of the collected water samples were performed for analysis of some selected physico-chemical parameters such as pH, EC, TDS, DO, COD, Total hardness, Fluoride, chloride etc. The methods employed for the analysis as per standard methods recommended by APHA and WHO standard of drinking water. The obtained values are compared with the standard limit. The results of this study reveals that in the industrial area of the physico-chemical parameters higher in the maximum permissible limit of WHO with variations in some parameters. Both the sampling stations groundwater unsuitable for domestic, irrigation and drinking purposes but the industrial area of BEC fertilizers groundwater is more polluted than the Adarsh nagar residential area of Sirgitti. So it is essential that the quality of ground water should be regular checked and also needs treatment before direct use.
An Integrated Model of Dissatisfaction Role in Understanding Post-Purchase Behavior in Sustainable Industry
Authors: Zrelli Imen 
Published: October 2023

This research proposes to apprehend the debate relating to the risks of tariff modulation in particular at the customers post-purchase behavior in sustainable industry. Each Price modulation generates a different reaction from customers. This reaction can take place on two levels. The first concerns the elasticity of demand with respect to price and the second concerns rather the perception of the service itself. The price elasticity of demand is one of the measures of the effectiveness of marketing actions and helps to understand the state and dynamics of markets. The higher the price, the lower the demand. Moreover, a minority of customers is ready to buy the same service at a higher price. Each price difference translates into a change in demand according to the elasticity. Tariff modulation as a strategic decision must be well studied before its implementation. This is because of its significant impact on the perception of the service, especially as customers link the price to other factors, including quality. To understand how customers perceive the price and consider bringing together services at different prices satisfying the same needs, we are going to conduct a field survey that will focus on the service sector, we are going to test the impact of dissatisfaction with Price modulation on post-purchase behavior and see how it plays a full mediating role between Price modulation and brand detachment. We chose the questionnaire survey method for clients, since it allows us to gather a large number of variables and provide operational measures of qualitative variables. This by using psychometric scales accompanied by attitude scales which make it possible to calculate scores for each respondent. In the conclusion, it would be interesting to concentrate the effort on the search for new managerial orientations concerning the application of transparency and relational.
Can Aggressive Marketing Cause an Ethical Dilemma?
Authors: Hashem Tareq N. 
Published: October 2023

Current aimed to answer the question of whether aggressive marketing (Intensity, Frequency, Intrusiveness, Personalization and Persistence) can be seen as an intruder to the ethical value of marketing tactics and strategies. Theoretical framework: Many organizations are seeking multiple approaches to market their product/services. Come of them do not give much attention to the marketing approach as long as it may comeback with profit and promotion to their products. One of these approaches are now called aggressive marketing which is based on organization taking risks and proactive tactics in order to guarantee its share in the market. Design/Methodology/Approach: Through quantitative methodology and a distribution of a questionnaire on (293) managers and officer within companies registered with the Companies Control Department. The answer to the question is the fact that YES, aggressive marketing can be a source of an ethical dilemma and companies must be careful not to cross ethical or legal boundaries in their marketing efforts, such as making false or misleading claims, using deceptive advertising, or engaging in unfair competition practices. Findings: Results also indicated that in some cases, aggressive of marketing can turn into harassment, with individuals receiving multiple phone calls, emails or direct mail that creates a sense of discomfort, anxiety or fear. Such marketing practices could be seen as abusive, unethical, and illegal. The level of intensity in aggressive marketing should be carefully calibrated to balance the need to generate sales with the need to maintain customer trust and brand reputation over the long term. Research, Practical & Social Implications: The theoretical implications of current study would involve examining the relationship between aggressive marketing tactics and their impact on the ethical framework of businesses, organizations and their stakeholders. On a practical level, the study's findings could have significant implications for the way in which companies approach marketing and promotions. Originality/value: The study could also highlight the importance of establishing clear ethical standards and guidelines for businesses and marketers, in order to prevent negative impact on customers and public perception.
The Aristotelian Conception of Principle as the Theoretical Foundation for a Healthy Cultural Relativism
Authors: Ibarra Silviano de Jesús Anda 
Published: October 2023

to elucidate if the three most accepted modalities of cultural relativism -descriptive, normative, and cognitive- are philosophically valid, and consequently healthy for knowledge development, cultural understandings, and knowledge reliability. Theoretical Framework: the theoretical ideas oscillated among the pure reasoning behind cultural relativism, culture theory, the premises of Husserl’s phenomenology, and the Aristotelian notions of principle and relation, among others. Design / Methodology / Approach: the Aristotelian dialectic, which poses an idea to discussion, analyzes it to discard any contradiction; if contradiction emerges, the data and notions behind the discussed idea are hierarchized to the main principles of knowledge for improvement or correction. Findings: the only valid and healthy modality of cultural relativism is the “descriptive” one because it truly seeks the approach and understanding of alterity/otherness as the cultural relativism reasoning claims. Research, Practical & Social implication: the configuration of normative and epistemological systems based on cultural relativism is contradictory, unhealthy, and dangerous for culture and research conclusions. Originality / Value: this work consists of the attempt to conciliate the foundations of western philosophy with the contemporary philosophical doctrines as an invitation to achieve the ideal of culture: set a proper world for humanity.
The Impact of Cancer on Mental Health
Authors: Ugur Kübra 
Published: October 2023

Cancer cases have grown significantly more dangerous as people's life expectancies have increased. In addition, cancer patients may experience serious mental health issues that hinder their recovery. There is a gap in cancer treatment where patients are frequently only treated for their cancer and the effects of cancer on mental health are usually ignored. Several psychiatric care programs are available to patients, but few people are aware of them, and cancer patients are not questioned regarding their attraction to these programs. The aim of the study is to analyze the impact of cancer on anxiety and depression level of cancer patients and to understand which prevention program is found more interesting by cancer patients. Seventy patients participated in this study. Hospital Anxiety and Depression Scale (HADS) has been used to measure anxiety and depression. According to the results, the average anxiety level was 9.36 ± 4.33, and the average depression level was 10.49 ± 3.50. Based on the program selection, the majority of participants selected "Support Groups" with a rate of 41.40%, and "Educational Programs" with a rate of 31.40%. In conclusion, the average anxiety level was at the borderline, and the average depression level was abnormal. This study shows that the mental health of cancer patients is neglected, and this issue is not sufficiently addressed. Future studies may focus on how to solve this problem more effectively and how to raise more awareness about the mental health of cancer patients.
Clinical Observation in Premature Babies with Feeding Intolerance
Authors: ÖZCAN Beyza , BÜYÜKEREN Melek , KENAR Aytaç , KEÇECİ Ramazan 
Published: October 2023

Objective: Feeding intolerance (FI) is a digestive disorder that manifests itself with gastric residue, abdominal distension, and vomiting, especially in preterm infants, and often causes a prolongation of the transition to full enteral feeding. Nutrition strategy is a significant clinical challenge for neonatologists. It is tried to treat feeding intolerance with methods such as minimal enteral nutrition and slow increase in sustenance, probiotic use, prevention/treatment of NEC and sepsis, and use of specially formulated foods, but these methods are only partially effective.
Methods: Babies under 32 weeks and 1500 g hospitalized in Konya City Hospital between August 2020 and January 2022 were evaluated retrospectively. Babies with and without feeding intolerance were divided into two groups, and their demographic and clinical conditions were examined. The treatment modalities of the group with feeding intolerance were evaluated.
Results: Of the 86 patients in the study, 36 were included in the FI group, and 50 were in the healthy control group. Late neonatal sepsis and duration of parenteral nutrition were found to be statistically significantly higher in the group with feeding intolerance compared to the control group (p