bluuebunny/crossref_metadata_2025_split huggingface dataset:
Timing, Indicators, and Approaches to Digital Patient Experience Evaluation: Umbrella Systematic Review
Authors: Wang Tingting , Giunti Guido , Goossens Richard , Melles Marijke 
Published: November 2023

Background
The increasing prevalence of DH applications has outpaced research and practice in digital health (DH) evaluations. Patient experience (PEx) was reported as one of the challenges facing the health system by the World Health Organization. To generate evidence on DH and promote the appropriate integration and use of technologies, a standard evaluation of PEx in DH is required.

Objective
This study aims to systematically identify evaluation timing considerations (ie, when to measure), evaluation indicators (ie, what to measure), and evaluation approaches (ie, how to measure) with regard to digital PEx. The overall aim of this study is to generate an evaluation guide for further improving digital PEx evaluation.

Methods
This is a 2-phase study parallel to our previous study. In phase 1, literature reviews related to PEx in DH were systematically searched from Scopus, PubMed, and Web of Science databases. Two independent raters conducted 2 rounds of paper screening, including title and abstract screening and full-text screening, and assessed the interrater reliability for 20% (round 1: 23/115 and round 2: 12/58) random samples using the Fleiss-Cohen coefficient (round 1: k1=0.88 and round 2: k2=0.80). When reaching interrater reliability (k>0.60), TW conducted the rest of the screening process, leaving any uncertainties for group discussions. Overall, 38% (45/119) of the articles were considered eligible for further thematic analysis. In phase 2, to check if there were any meaningful novel insights that would change our conclusions, we performed an updated literature search in which we collected 294 newly published reviews, of which 102 (34.7%) were identified as eligible articles. We considered them to have no important changes to our original results on the research objectives. Therefore, they were not integrated into the synthesis of this review and were used as supplementary materials.

Results
Our review highlights 5 typical evaluation objectives that serve 5 stakeholder groups separately. We identified a set of key evaluation timing considerations and classified them into 3 categories: intervention maturity stages, timing of the evaluation, and timing of data collection. Information on evaluation indicators of digital PEx was identified and summarized into 3 categories (intervention outputs, patient outcomes, and health care system impact), 9 themes, and 22 subthemes. A set of evaluation theories, common study designs, data collection methods and instruments, and data analysis approaches was captured, which can be used or adapted to evaluate digital PEx.

Conclusions
Our findings enabled us to generate an evaluation guide to help DH intervention researchers, designers, developers, and program evaluators evaluate digital PEx. Finally, we propose 6 directions for encouraging further digital PEx evaluation research and practice to address the challenge of poor PEx.
Mobile Prenatal Education and Its Impact on Reducing Adverse Pregnancy Outcomes: Retrospective Real-World Study
Authors: Hao Jie , Yang Lin , Wang Yaxin , Lan Yushan , Xu Xiaowei , Wang Ziyang , Li Zanmei , Ma Liangkun , Li Jiao , Zhang Suhan , Sun Yin 
Published: November 2023

Background
Pregnancy is a pivotal phase in a woman’s life, demanding special attention to ensure maternal and fetal health. Prenatal education plays a vital role in promoting healthy pregnancies and reducing adverse outcomes for pregnant women. Mobile prenatal education programs have gained traction due to their accessibility and timeliness, especially in light of finite health care resources and the constraints imposed by the COVID-19 pandemic.

Objective
This study aims to develop and evaluate the effectiveness of a mobile-based prenatal education program in improving pregnancy outcomes.

Methods
We developed a mobile-based prenatal education curriculum in collaboration with a multidisciplinary maternal care team from Peking Union Medical College Hospital (PUMCH) in Beijing, China. Data were retrospectively collected from 1941 pregnant women who had registered for the PUMCH mobile prenatal education program and subsequently delivered at PUMCH between May 2021 and August 2022. The study compared pregnancy outcomes between the completing group, which were pregnant women who had completed at least 1 course, and the noncompleting group. We also analyzed differences among course topics within the completing group and assessed course topic popularity among pregnant women.

Results
The PUMCH mobile prenatal education curriculum consists of 436 courses across 9 topics. Out of the participants, a total of 1521 did not complete any courses, while 420 completed at least 1 course. Compared with the noncompleting group, pregnant women who completed courses exhibited a significant reduction in the risk of gestational diabetes mellitus, induced abortion, postpartum infection, fetal intrauterine distress, and neonatal malformation. Among those in the completing group, a total of 86% (361/420) started course completion during the first and second trimesters. Furthermore, completing courses related to topics of pregnancy psychology and pregnancy nutrition was associated with reduced risks of premature rupture of membranes and small for gestational age infants, respectively. Pregnancy psychology and postpartum recovery were the preferred topics among pregnant women.

Conclusions
The study demonstrates the potential of mobile-based prenatal education programs in improving pregnancy outcomes and supporting health care providers in delivering effective prenatal education. The rise of mobile prenatal education presents an opportunity to improve maternal and child health outcomes. Further research and broader implementation of such programs are warranted to continually improve maternal and child health.
Diabetes Risk Factors and Bone Microarchitecture as Assessed by High-Resolution Peripheral Quantitative Computed Tomography in Adults With Long-standing Type 1 Diabetes
Authors: Sinha Gregory Naina , Burghardt Andrew J. , Backlund Jye-Yu C. , Rubin Mishaela R. , Bebu Ionut , Braffett Barbara H. , Kenny David J. , Link Thomas M. , Kazakia Galateia J. , Barnie Annette , Lachin John M. , Gubitosi-Klug Rose , de Boer Ian H. , Schwartz Ann V. ,   DCCT/EDIC Research Group
Published: November 2023

OBJECTIVE
To determine whether type 1 diabetes and its complications are associated with bone geometry and microarchitecture.

RESEARCH DESIGN AND METHODS
This cross-sectional study was embedded in a long-term observational study. High-resolution peripheral quantitative computed tomography (HR-pQCT) scans of the distal radius and distal and diaphyseal tibia were performed in a subset of 183 participants with type 1 diabetes from the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications (DCCT/EDIC) study and 94 control participants without diabetes. HbA1c, skin advanced glycation end products (AGEs), and diabetes-related complications were assessed in EDIC participants with &gt;30 years of follow-up.

RESULTS
Compared with control participants (aged 60 ± 8 years, 65% female), EDIC participants (aged 60 ± 7 years, diabetes duration 38 ± 5 years, 51% female) had lower total bone mineral density (BMD) at the distal radius (−7.9% [95% CI −15.2%, −0.6%]; P = 0.030) and distal tibia (−11.3% [95% CI −18.5%, −4.2%]; P = 0.001); larger total area at all sites (distal radius 4.7% [95% CI 0.5%, 8.8%; P = 0.030]; distal tibia 5.9% [95% CI 2.1%, 9.8%; P = 0.003]; diaphyseal tibia 3.4% [95% CI 0.8%, 6.1%; P = 0.011]); and poorer radius trabecular and cortical microarchitecture. Estimated failure load was similar between the two groups. Among EDIC participants, higher HbA1c, AGE levels, and macroalbuminuria were associated with lower total BMD. Macroalbuminuria was associated with larger total area and lower cortical thickness at the distal radius. Higher HbA1c and AGE levels and lower glomerular filtration rate, peripheral neuropathy, and retinopathy were associated with deficits in trabecular microarchitecture.

CONCLUSIONS
Type 1 diabetes is associated with lower BMD, larger bone area, and poorer trabecular microarchitecture. Among participants with type 1 diabetes, suboptimal glycemic control, AGE accumulation, and microvascular complications are associated with deficits in bone microarchitecture and lower BMD.
Faktor Kepatuhan Perawat Dalam Penerapan Surgical Safety Checklist di Instalasi Bedah Sentral
Authors: Risanti Rahmah Dyla , Purwanti Ery , Novyriyana Eka 
Published: November 2023

Abstrak: Latar Belakang; Angka terjadinya kasus kecelakaan di kamar bedah sangat tinggi, karena dalam pelaksanaannya tidak memperhatikan pasien, dan prosedur operasi. Hal ini dapat dicegah dengan diterapkannya Surgical Safety Checklist, dimana tim bedah harus patuh melaksanakan setiap poin di dalam checklist sehingga dapat meminimalkan setiap risiko yang tidak diinginkan. Tujuan Penelitian; Untuk mengetahui faktor yang berhubungan dengan kepatuhan perawat terhadap penerapan Surgical Safety Checklist di Instalasi Bedah Sentral RSUD KRT. Setjonegoro Wonosobo. Metode; Penelitian ini menggunakan jenis analitik korelatif dengan pendekatan cross- sectional. Sampel 24 orang dengan teknik total sampling. Analisis :Penelitian ini menggunakan analisis Chi-square untuk analisis bivariat. Hasil; Terdapat hubungan yang signifikan (nilai p 0,05) antara usia (nilai X2 = 7,726 dan nilai p = 0,005), pendidikan (nilai X2 = 4,800 dan nilai p = 0,028), masa kerja (nilai X2 = 6,507 dan nilai p = 0,039), motivasi (nilai X2 = 16,471 dan nilai p = 0,000), sikap (nilai X2 = 10,526 dan nilai p = 0,005), dan pengetahuan (nilai X2 = 7,313 dan nilai p = 0,026) dengan kepatuhan perawat dalam penerapan Surgical Safety Checklist. Sedangkan tidak ada hubungan yang signifikan antara jenis kelamin dengan kepatuhan perawat dalam penerapan Surgical Safety Checklist, nilai X2 = 0,059 dan nilai p = 0,808 (p0,05). Kesimpulan; Ada hubungan antara usia, pendidikan, masa kerja, motivasi, sikap, dan pengetahuan dengan kepatuhan perawat terhadap penerapan Surgical Safety Checklist di Instalasi Bedah Sentral RSUD KRT. Setjonegoro Wonosobo, serta tidak ada hubungan antara jenis kelamin dengan kepatuhan perawat terhadap penerapan Surgical Safety Checklist di Instalasi Bedah Sentral RSUD KRT. Setjonegoro Wonosobo. Rekomendasi; Perawat diharapkan lebih meningkatkan kepatuhan akan penerapan Surgical Safety Checklist karena sangat berpengaruh dalam keselamatan pasien di kamar operasi.Kata kunci: Kepatuhan, Surgical Safety Checklist, Instalasi Bedah Sentral
GEOMORPHIC INDICES AND FAULT SEGMENTATION INDICATION OF MENANGA FAULT AT PESAWARAN, LAMPUNG
Authors: Hendrawan Rezki Naufan , Draniswari Windi Anarta , Bakhtiar Agim Yustian , Widiatama Angga Jati 
Published: November 2023

Remote sensing and GIS are playing important roles in geomorphology and hazard risks analysis. Pesawaran area located near the Menanga Fault and recently on the risk of earthquake that happened along this fault. Thus, it is essential to investigate the area actively affected by Menanga Fault as preliminary research about hazard risk related to Menanga Fault. The morphometry method based on DEMNAS and Landsat 8 was applied to evaluate the zone affected by Menanga Fault, and fracture data analysis was conducted to consider the possibility of fault segmentation resulting from its mechanism. The study area can be divided into 3 zones; zone A is greatly affected by Menanga Fault activity, zone B is affected by Menanga Fault and Mt. Pesawaran development, and zone C is tectonically less affected. Zone A landforms were not only formed as a result of Menanga Thrust fault but also the strike-slip fault segment. Fault segmentation exists in this zone with different mechanisms (strike-slip and dip-slip), producing lineaments with different trends, and differentiation of river patterns.
MIKROZONASI TINGKAT KERENTANAN LAPISAN TANAH KECAMATAN NAMBO, KENDARI MENGGUNAKAN METODE HORIZONTAL-TO-VERTICAL SPECTRAL RATIO
Authors: Rubaiyn Al , Hamimu La , Mukarramah Mukarramah 
Published: November 2023

Penelitian respons dinamik dan indeks kerentanan seismik sangat penting untuk memperkirakan dampak kerentanan lapisan permukaan dan kerusakan bangunan ketika terjadi gempa bumi. Penelitian ini bertujuan untuk mengidentifikasi respons dinamik Kecamatan Nambo, Kota Kendari serta menentukan area-area dengan perlapisan tanah yang sangat rentan. Data mikrotremor diolah menggunakan Geopsy 2.0.5 untuk memperoleh kurva HVSR (Horizontal to Vertical Spectral Ratio) serta parameter respons dinamik tanah berupa frekuensi dominan dan faktor amplifikasinya yang digunakan untuk menghitung indeks kerentanan seismik. Nilai frekuensi dominan Kecamatan Nambo berkisar antara 0,7 Hz- 3,63 Hz yang termasuk dalam kategori tanah Tipe II dan III. Area dengan frekuensi rendah menunjukkan penebalan lapisan alluvial yang merupakan produk sedimentasi permukaan. Interpolasi nilai indeks kerentanan seismik (kg) menunjukkan area Kecamatan Nambo yang memiliki kerentanan tinggi meliputi Kelurahan Pentoahan dan Nambo.
ANALISIS TENSOR FASE DAN PEMODELAN 2D DATA MAGNETOTELURIK GABBS VALLEY, NEVADA, USA
Authors: Pahri Pahri , Paembonan Andri Yadi , Irawati Selvi Misnia 
Published: November 2023

Metode magnetotellurik (MT) merupakan salah satu teknik dalam metode geofisika yang menggunakan sumber alami dalam bentuk medan elektromagnetik yang berasal dari medan listrik dan variasi medan magnet di bumi. Dalam proses interpretasi kondisi bawah permukaan bumi, data MT masih dipengaruhi oleh noise atau distorsi yang akan menutupi dimensionalitas sebenarnya. Oleh karena itu dilakukan analisis tensor fase untuk menentukan dimensionalitas dan arah geoelectrical strike guna mengidentifikasi struktur bawah permukaan yang tidak dipengaruhi oleh distorsi galvanic. Berdasarkan hasil yang diperoleh, daerah penelitian memiliki dimensionalitas 2D dengan orientasi barat laut – tenggara dengan arah N345 E. Hasil inversi 2D menunjukkan bahwa nilai resistivitas 10 diidentifikasi sebagai zona alterasi atau clay cap yang didominasi oleh mineral smektit. Nilai resistivitas 20 – 250 diidentifikasi sebagai reservoar yang bersifat permeabel yang tersusun atas batu pasir kasar, kerikil, basal, andesit, riolit, riodasit tuff dan konglomerat. Lapisan dengan nilai resistivitas 250 diidentifikasi sebagai Upper Triassic Metasediment yang mengalami sedimentasi yang sangat keras, hal tersebut disebabkan tekanan dan suhu tinggi. Lapisan ini tersusun atas meta batu lanau, batu lempung, meta batu pasir, dan meta konglomerat.
Upaya Menciptakan Sanitasi di Lingkungan Peternakan Dengan Pendekatan Perilaku Hidup Bersih Dan Sehat (PHBS)
Authors: HARLIA ELLIN , Hidayati Yuli Astuti , Marlina Eulis Tanti , Rahmah Khairunnisa Nur 
Published: November 2023

Pemerintah menerapkan sejumlah kebijakan untuk antisipasi penyebaran COVID-19,salah satunya adalah pengenalan protokol kesehatan 5M. Salah satu cara yang dapat dilakukan masyarakat dalam menjaga kebersihan dan kesehatan tubuh adalah dengan menerapkan Perilaku Hidup Bersih dan Sehat (PHBS) di semua lingkungan termasuk lingkungan peternakan. Sasaran dari PKM ini yaitu siswa SMPN 3 Jatinangor kelas 7 dan 9. lokasi SMPN 3 berhadapan dengan peternakan sapi populasi 350 ekor dan sebagian siswa memelihara ternak di rumahnya. PKM dilakukan pada RW 11 dusun Cikeuyeup desa Cilayung Kecamatn Jatinangor Kabupaten Sumedang, Tujuan utama dari gerakan PHBS adalah meningkatkan kualitas kesehatan masyarakat melalui proses edukasi sebagai bagian awal dari kontribusi setiap individu untuk menjalani kehidupan sehari-hari yang bersih dan sehat. untuk mencegah masuknya bibit penyakit di lingkungan peternakan, dan mendukung tujuan pembangunan berkelanjutan (Sustainable Development Globals). Metode kegiatan yang dilakukan untuk PHBS melalui story telling, penyuluhan dan demonstrasi pembuatan kompos dan biogas kepada siswa SMPN 3 Jatinangor. Berdasarkan hasil pengolahan data dengan menggunakan descriptive statistics, terdapat peningkatan pemahaman siswa mengenai PHBS setelah dilakukan sosialisasi. Pemberian materi dalam bentuk story telling, siswa menjadi lebih paham mengenai perilaku hidup bersih dan sehat di lingkungan peternakan. Tindak lanjutnya yaitu melakukan donasi poster tentang sanitasi lingkungan, sanitasi individu, sanitasi pangan hasil ternak kepada SMPN 3.
Early decrease of ionized calcium and static symmetric dimethylarginine concentration in a model of renal tubular necrosis in corn snakes (Pantherophis guttatus)
Authors: Vergneau-Grosset Claire , Pujol Julie , Rubin Bastien , Romano Noriega Jacobo , Gara-Boivin Carolyn , Chorfi Younes , Ferrell Shannon , Lair Stéphane 
Published: November 2023

Abstract

OBJECTIVE
To determine if plasma concentrations of symmetric dimethylarginine (SDMA), N-acetyl-beta-d-glucosaminidase (NAG), GGT, ALT, AST, lactate, total calcium, and ionized calcium (iCa) and the calcium:phosphorus ratio are clinically relevant biomarkers to detect early stages of tubular lesions in snakes.

ANIMALS
6 adult corn snakes (Pantherophis guttatus).

METHODS
Corn snakes were administered 11 injections of gentamicin at 50 mg/kg, SC, q 24 h in an experimental model of induced tubular necrosis. Plasma biochemistry and blood gas analyses were performed at baseline and after the 3rd and 11th injections. Parameters were compared between time points using a paired Wilcoxon test. In 3 individuals, renal biopsies were collected at baseline before starting injections and at the 3rd and 11th injections, while renal tissue samples were procured after euthanasia in all individuals.

RESULTS
Renal proximal and distal tubular necrosis and hepatic steatosis were present in all individuals at necropsy. Compared to baseline, decreased blood concentrations of lactate, ionized calcium, and total calcium and a decreased calcium:phosphorus ratio were noted. A significant decrease of lactate and ionized calcium was observed after 3 days. Conversely, no changes in SDMA, NAG, ALT, AST, GGT, and sodium were detected.

CLINICAL RELEVANCE
Ionized calcium and lactate concentrations were the earliest parameters to decrease compared to baseline values in this experimental model. While SDMA is a sensitive indicator of renal disease in mammals, this biomarker did not increase in a model of induced acute tubular necrosis in corn snakes.
Pharmacokinetics of single-dose oral atorvastatin and its metabolites support therapeutic use in orange-winged Amazon parrots (Amazona amazonica)
Authors: Mikoni Nicole , Guzman David Sanchez-Migallon , Knych Heather , Beaufrère Hugues 
Published: November 2023

Abstract

OBJECTIVE
To evaluate the plasma concentrations and determine pharmacokinetic parameters of atorvastatin and its primary active metabolites (para- and ortho-hydroxyatorvastatin) after administration of a single oral dose in orange-winged Amazon parrots (Amazona amazonica).

ANIMALS
8 adult orange-winged Amazon parrots (4 male, 4 female) of varying ages.

METHODS
A compounded oral suspension of atorvastatin 10 mg/mL was administered via oral gavage at 20 mg/kg to each bird. Blood samples were collected at 10 different time points from 0 to 30 hours postadministration to evaluate plasma levels of atorvastatin, para-hydroxyatorvastatin, and ortho-hydroxyatorvastatin. Pharmacokinetic analysis was performed using noncompartmental analysis and commercially available software.

RESULTS
Mean ± SD atorvastatin half-life, tmax, and Cmax were 5.96 ± 11.50 hours, 1.60 ± 0.80 hours, and 82.60 ± 58.30 ng/mL, respectively. For para-hydroxyatorvastatin, the half-life, tmax, and Cmax were 6.46 ± 54.20 hours, 5.00 ± 2.51 hours, and 34.10 ± 16.00 ng/mL, respectively, and 5.58 ± 9.92 hours, 3.38 ± 2.10 hours, and 7.35 ± 3.96 ng/mL for ortho-hydroxyatorvastatin.

CLINICAL RELEVANCE
The plasma concentrations and pharmacokinetic profile shown support the therapeutic use of atorvastatin at the dose evaluated in this species based on human pharmacokinetic data. While 20 mg/kg PO q24 hours could be used as a starting dosage until further studies evaluating multiple dose administration and efficacy in this species become available, the high interindividual variability results warrant monitoring of the treatment response to make dosing adjustments if needed.
LEMBAGA NIRLABA, UMKM DAN SPIRITUALITAS MANAJEMEN KEUANGAN
Authors: Purbiyati Yuliana Sri , Widyastuti Maria , Putri Pricilla Angelita 
Published: November 2023

Spiritualitas manajemen keuangan merupakan landasan dalam pelaksanaan pengelolaan keuangan di Gereja Katolik. Sekalipun sebagai lembaga nirlaba, Gereja tetap memiliki keterlibatan dalam hal pemberdayaan perekonomian masyarakat. Penelitian ini merupakan penelitian kualitatif dengan metode etnografi. Fokus penelitian adalah dampak penerapan spiritualitas manajemen keuangan terhadap pemberdayaan ekonomi masyarakat. Penelitian dilaksanakan di Gereja Katolik Kevikepan Surabaya Barat Keuskupan Surabaya. Hasil penelitian ini adalah Gereja Katolik Kevikepan Surabaya Barat Keuskupan Surabaya melaksanakan spiritualitas manajemen keuangan yang berdampak pada perekonomian masyarakat dengan pembentukan UMKM untuk jemaat dan masyarakat di sekitarnya. Salah satu Gereja ditunjuk sebagai pelaksana untuk role model. Dari satu Gereja tersebut kemudian akan terus dilaksanakan di Gereja-Gereja lain sehingga semua Gereja Gereja Katolik Kevikepan Surabaya Barat Keuskupan Surabaya melaksanakan pendampingan pemberdayaan ekonomi masyarakat.
Analisis Gaya Kepemimpinan Demokratis dan Kaderisasi Kepemimpinan terhadap Kinerja Karyawan
Authors: Nurwahidah Sita , Muhamad Ramdan Asep , Mulia Z Faizal 
Published: November 2023

The purpose of this study was to determine the influence of democratic leadership style and leadership regeneration on employee performance at PT Harendong Green Farm Lebak-Banten. The method used in this research is descriptive and associative research with a quantitative approach. The sampling technique in this study used saturated sampling, the samples taken in this study were 30 employees. Data analysis techniques used validity and reliability tests, classic assumption tests, multiple linear regression including correlation coefficients, determination, research model testing and research hypothesis testing. The results of the study using the coefficient of determination test (R2) show that democratic leadership and regeneration of leadership affect employee performance by 35.28% while the remaining 64.72% is influenced by other factors outside of this study. Based on the multiple correlation coefficient test, it can be seen from the R value of 0.594 which means that there is a moderate relationship between democratic leadership and leadership regeneration on employee performance. The results of the F test, namely the value of Fcount 7.371> F table 3.340 indicates that Fcount is greater than Ftable. The variables of democratic leadership and leadership regeneration have a positive and significant effect on employee performance.
Keywords : Democratic Leadership Style, Leadership Regeneration Employee Performance