bluuebunny/crossref_metadata_2025_split huggingface dataset:
Appendiceal duplication an unusual cause of abdominal pain: A case report
Authors: Molla Yohannis Derbew , Sisay Menarguachew Atanaw , Abera Samuel Addisu , Abebe Bewketu , Adisu Girma Damtew 
Published: December 2023

Key Clinical MessageAppendiceal duplication is exceedingly rare, with a prevalence of 0.004% to 0.009% in appendectomy specimens. Appendiceal duplications can occur alone or in conjunction with cecal duplication. The persistence of the temporary embryologic second cecal appendix is hypothesized to cause appendiceal duplications. We present a case of appendiceal duplication in a 26‐year‐old Ethiopian female patient who had been experiencing abdominal pain in the right lower quadrant for 1 week. She developed anorexia, a loss of appetite, and a low‐grade fever as a result of this. She reported direct and rebound mild discomfort in the right lower quadrant on abdominal examination. She was then operated on and she had an appendiceal duplication intraoperatively. As a result, an appendectomy was performed, and the patient was discharged with improved health. To avoid unfavorable patient outcomes and medicolegal difficulties, surgeons and surgical trainees who conduct several appendectomies throughout their training should be aware of the likelihood of appendiceal duplication.
Generalist and topologically central avian frugivores promote plant invasion unequally across land‐bridge islands
Authors: Zhu Chen , Dalsgaard Bo , Li Wande , Gonçalves Fernando , Vollstädt Maximilian G. R. , Ren Peng , Zhang Xue , Shao Junjie , Ding Ping , Si Xingfeng 
Published: December 2023

AbstractSeed dispersal by frugivorous birds facilitates plant invasions, but it is poorly known how invasive plants integrate into native communities in fragmented landscapes. We surveyed plant–frugivore interactions, including an invasive plant (Phytolacca americana), on 22 artificial land‐bridge islands (fragmented forests) in the Thousand Island Lake, China. Focusing on frugivory interactions that may lead to seed dispersal, we built ecological networks of studied islands both at the local island (community) and at landscape (metacommunity) levels. On islands with P. americana, we found that P. americana impacted local avian frugivory networks more on islands with species‐poor plant communities and on isolated islands. Moreover, as P. americana interacted mainly with local core birds (generalists), this indicates reduced seed dispersal of native plants on invaded islands. At the landscape level, P. americana had established strong interactions with generalist birds that largely maintain seed‐dispersal functions across islands, as revealed by their topologically central roles both in the regional plant–bird trophic network and in the spatial metanetwork. This indicates that generalist frugivorous birds may have facilitated the dispersal of P. americana across islands, making P. americana well integrated into the plant–frugivore mutualistic metacommunity. Taken together, our study demonstrates that the impact of plant invasion is context‐dependent and that generalist native frugivores with high dispersal potential may accelerate plant invasion in fragmented landscapes. These findings highlight the importance of taking the functional roles of animal mutualists and habitat fragmentation into account when managing plant invasions and their impact on native communities.
A review on thermogravimetric analysis‐based analyses of the pyrolysis kinetics of oil shale and coal
Authors: Li Yaoyu , Li Jing , Zhou Shixin , Meng Bingkun , Wu Tao 
Published: December 2023

AbstractSolid fossil fuels still support the development of the energy and chemical industry. The clean and efficient utilization of solid fossil fuels can effectively alleviate the problems of energy shortage and environmental pollution. An in‐depth understanding of the kinetic process, models, and mechanism of pyrolysis of solid fossil fuels is also of great significance for the exploration and utilization technologies of petroleum resources. Thermogravimetric analysis is an effective method to study the pyrolysis process and kinetics with the advantages of high sensitivity, repeatability, and reliability for data acquisition. Researchers have conducted a lot of research on the thermogravimetric kinetics of solid fossil fuels in recent years, but there is a lack of systematic summary and comparison of kinetic methods, research progress, and trends. Therefore, a comprehensive study on pyrolysis kinetic principles, methods, and models of solid fossil fuels by thermogravimetric analysis is carried out in this paper. The influencing factors of pyrolysis kinetics of solid fossil fuels using thermogravimetry are elaborated and discussed in detail. This study also provides progress in recent years and prospects of thermogravimetric kinetics of solid fossil fuels. It is expected that this paper can provide certain technical support and theoretical guidance for the research on pyrolysis kinetics based on thermogravimetric analysis, and the exploration and development, clean, and efficient utilization of solid fossil fuels.
Affective theory of mind in people with mild and moderate Alzheimer's disease
Authors: de Lucena Aline Tavares , Dos Santos Tatiana Teresa Belfort Almeida , Santos Paulo Fernando Alves , Dourado Márcia Cristina Nascimento 
Published: December 2023

AbstractObjectiveThis study compared the affective theory of mind (ToM) of people with mild and moderate Alzheimer's disease (AD) and healthy older adults and also investigated the relationship between affective ToM and cognitive and clinical functioning in AD people.MethodsThis cross‐sectional study included 156 older adults with AD and 40 healthy older adults. We used an experimental task involving reasoning processes in different contextual situations.ResultsThe affective ToM was impaired in AD groups compared with healthy group, with moderate AD group showing lower performance than mild AD group. The affective ToM task of mild AD group was significantly correlated with the Mini‐Mental State Examination (MMSE) and education years. Linear regression showed only education years as a predictor of ToM task performance. The neuropsychiatric symptoms and functionality were not correlated with the affective ToM.ConclusionsOur findings demonstrated that people with mild and moderate AD presented impairments in affective ToM that can be explained by the difficulties to infer emotion from reasoning processes. In addition, the education years variable proved to be an affective ToM performance's predictor for the mild AD group, but not for the moderate AD group, indicating that ToM abilities are affected differently in different stages of AD. Neuropsychiatric symptoms and functionality seem to have no influence on affective ToM impairments in people with AD.
Small and state‐funded: An empirical study of liquidations in Scotland
Authors: Hardman Jonathan , MacPherson Alisdair 
Published: December 2023

AbstractThere is significant scope for empirical research in the field of corporate insolvency law. This paper seeks to make a valuable contribution to this field of research. It features analysis of data regarding all insolvent liquidations in Scotland that had their end point within a period of a year, specifically 1 October 2019‐30 September 2020 (even if the liquidations commenced prior to that period). A dataset was compiled using information from final accounts documentation for liquidations available from the UK's companies register. Following the introduction, the paper provides background and context for corporate insolvency in Scotland, with particular reference to liquidation and the rules relating to creditors. The section also includes comparisons with the law of England and Wales. The paper then moves on to discuss the empirical methodology adopted and how the relevant data was obtained. This is followed by results and analysis focused on: the asset values of companies in the study, the lifespan of those companies, the timespan of their liquidations, the levels of liquidation expenses, the recoveries of creditors (including secured, preferential and ordinary unsecured creditors), and the role of HMRC in liquidations, as a petitioner and in terms of paying liquidation expenses. The paper contains a number of significant findings regarding each of these matters. It supports the case for a streamlined liquidation procedure for smaller companies and for the introduction of an official receiver in Scotland (while also justifying the existence of the official receiver in England and Wales). Lastly, after the identification of some limitations regarding the analysed data, the paper highlights potential lines of further research building upon this study, including expanding the time periods examined, comparing the data for Scotland with data for other jurisdictions, most obviously England and Wales, and the consideration of corresponding data for other insolvency procedures.
Ubiquitin‐specific protease 22 promotes tumorigenesis and progression by an FKBP12/mTORC1/autophagy positive feedback loop in hepatocellular carcinoma
Authors: Ye Qianwei , Zhou Wei , Xu Shengjun , Que Qingyang , Zhan Qifan , Zhang Lincheng , Zheng Shusen , Ling Sunbin , Xu Xiao 
Published: December 2023

AbstractUbiquitin‐specific protease 22 (USP22) has been identified as a potential marker for cancer stem cells in hepatocellular carcinoma (HCC). It can promote HCC stemness, which is considered a driver of tumorigenesis. Here, we sought to determine the role of USP22 in tumorigenesis, elucidate its underlying mechanism, and explore its therapeutic significance in HCC. As a result, we found that tissue‐specific Usp22 overexpression accelerated tumorigenesis, whereas Usp22 ablation decelerated it in a c‐Myc/NRasGV12‐induced HCC mouse model and that the mammalian target of rapamycin complex 1 (mTORC1) pathway was activated downstream. USP22 overexpression resulted in increased tumorigenic properties that were reversed by rapamycin in vitro and in vivo. In addition, USP22 activated mTORC1 by deubiquitinating FK506‐binding protein 12 (FKBP12) and activated mTORC1, in turn, further stabilizing USP22 by inhibiting autophagic degradation. Clinically, HCC patients with high USP22 expression tend to benefit from mTOR inhibitors after liver transplantation (LT). Our results revealed that USP22 promoted tumorigenesis and progression via an FKBP12/mTORC1/autophagy positive feedback loop in HCC. Clinically, USP22 may be an effective biomarker for selecting eligible recipients with HCC for anti‐mTOR‐based therapy after LT.
Order‐dependent sampling control for state estimation of uncertain fractional‐order neural networks system
Authors: Ge Chao , Zhang Qi , Wang Hong , Wang Lei 
Published: December 2023

AbstractIn this paper, the problem of state estimation for a fractional‐order neural networks system with uncertainties is studied by a sampled‐data controller. First, considering the convenience of digital field, such as anti‐interference, not affected by noise, a novel sampled‐data controller is designed for the fractional‐order neural network system of uncertainties with changeable sampling time. In the light of the input delay approach, the sampled‐data control system of fractional‐order is simulated by the delay system. The main purpose of the presented method is to obtain a sampled‐data controller gain to estimate the state of neurons, which can guarantee the asymptotic stability of the closed‐loop fractional‐order system. Then, the fractional‐order Razumishin theorem and linear matrix inequalities (LMIs) are utilized to derive the stable conditions. Improved delay‐dependent and order‐dependent stability conditions are given in the form of LMIs. Furthermore, the sampled‐data controller can be acquired to promise the stability and stabilization for fractional‐order system. Finally, two numerical examples are proposed to demonstrate the effectiveness and advantages of the provided method.
Two distinct mechanisms of flavoprotein spectral tuning revealed by low‐temperature and time‐dependent spectroscopy
Authors: Nikolaev Andrey , Tropina Elena V. , Boldyrev Kirill N. , Maksimov Eugene G. , Borshchevskiy Valentin , Mishin Alexey , Yudenko Anna , Kuzmin Alexander , Kuznetsova Elizaveta , Semenov Oleg , Remeeva Alina , Gushchin Ivan 
Published: December 2023

AbstractFlavins such as flavin mononucleotide or flavin adenine dinucleotide are bound by diverse proteins, yet have very similar spectra when in the oxidized state. Recently, we developed new variants of flavin‐binding protein CagFbFP exhibiting notable blue (Q148V) or red (I52V A85Q) shifts of fluorescence emission maxima. Here, we use time‐resolved and low‐temperature spectroscopy to show that whereas the chromophore environment is static in Q148V, an additional protein‐flavin hydrogen bond is formed upon photoexcitation in the I52V A85Q variant. Consequently, in Q148V, excitation, emission, and phosphorescence spectra are shifted, whereas in I52V A85Q, excitation and low‐temperature phosphorescence spectra are relatively unchanged, while emission spectrum is altered. We also determine the x‐ray structures of the two variants to reveal the flavin environment and complement the spectroscopy data. Our findings illustrate two distinct color‐tuning mechanisms of flavin‐binding proteins and could be helpful for the engineering of new variants with improved optical properties.
Construction of 2D layered metal‐organic frameworks based on the norbornene‐derived ligand with fascinating magnetic and luminescent properties
Authors: Ding Shuolei , Zhang Chuanqi , Yin Jianhang , Zhao Tao , Zhu Pengli , Sun Rong , Wang Ning 
Published: December 2023

AbstractThree new two‐dimensional metal‐organic frameworks (MOFs), namely [Cu3(NDIC)3 ⋅ C2H5OH ⋅ 2H2O]n (1), [Co2(NDIC)2 ⋅ 2 C3H7NO ⋅ H2O]n ⋅ nC2H5OH (2) and [(Zn3O)2(Zn(H2O)4)(NDIC)6 ⋅ C3H7NO ⋅ C2H5OH ⋅ C2H5O ⋅ 7H2O]n (3) based on the ligand 5‐norbonene‐2,3‐dicarboximide isophthalic acid (H2NDIC) have been synthesized under solvothermal condition, which have been further characterized by single crystal X‐ray diffraction analysis, powder X‐ray diffraction ( PXRD) elemental analysis, ICP, TG and FT‐IR spectroscopy. The ligand displayed distinctive coordination modes to connect mononuclear metal ion, binuclear and trinuclear metal clusters to generate different 2D layered structures in compound 1–3. Compound 1 shows KGM type network based on paddle‐wheel Cu2(COO)4 as secondary building units (SBUs). Compounds 2 and 3 have the undulating 2D (4, 4) SQL topology with the point symbol (44 ⋅ 62) based on Co2(COO)4 and Zn3(μ3‐O)(COO)4 as SBUs, respectively. The magnetic properties of compound 1–2 and the luminescent property of compound 3 and its fluorescent detection for Fe3+ has been investigated and discussed.
Development of a Highly Boron Tolerant Pseudomonas sp.−Fe‐MOF Bioanode
Authors: Avcı Okan , Sezer Kürkçü Merve , Çöl Bekir , Sonay Elgin Emine , Anık Ülkü 
Published: December 2023

AbstractIn this work, a bioanode which was based on carbon felt electrode (CFE) that contained highly boron tolerant bacterium Pseudomonas sp. isolated from a boron mine (Pseudomonas isolate BC4B) and iron‐metal organic framework (Fe‐MOF) was developed. To the best of our knowledge, this is the first study in which a highly boron tolerant bacterium, Pseudomonas isolate BC4B was investigated as a bioanode material. It was observed that Fe‐MOF increased the signal significantly by behaving as a catalyst. During the study, the optimization of Fe‐MOF amount, bacteria amount and substrate concentration were done. Also, the effect of different substrate amounts on the bioanode electrochemical signal was investigated. Consequently, the highest current density value was obtained with 5 mM substrate amount. Meanwhile, in order to investigate the reproducibility of developed bioanode, relative standard deviation value was calculated and found as 1.39 % (n : 3) for 4 mM concentration of H3BO3.
B‐Doping Induced Formation of Ultrafine Co Nanoparticles for Highly Sensitive Non‐Enzymatic Glucose Sensing
Authors: Yin Hang , Zhang Chongchao , Bai Xiao , Yang Ziyin , Liu Zhe 
Published: December 2023

AbstractDoping is one of the effective methods to improve the performance of sensors. Here, we reported that B‐doping can induce the formation of ultrafine Co nanoparticles for realizing highly sensitivity non‐enzymatic glucose sensing. Co/NC and Co/BNC were prepared by ion exchange and pyrolysis methods. It is interesting to find that B doping can achieve spatial isolation and prevent metal aggregation during MOF pyrolysis. This made the particle size of Co nanoparticles smaller and more uniform, which enriches the active site and thus improves the sensing performance for glucose. The electrochemical results indicate that Co/BNC exhibits strong electrocatalytic activity toward glucose oxidation and the non‐enzymatic sensor based on Co/BNC shows excellent performance for glucose analysis with a wide linear range of 0.4 μM–0.522 mM, a high sensitivity of 1064.3 μA mM−1 cm−2 and a low detection limit of 0.08 μM (S/N=3). Therefore, this study demonstrated Co/BNC as a promising glucose sensing material and also provided a novel strategy for improving electrochemical sensing performance through doping.
Effect of interfacial modification on functional properties of polyethylene and polypropylene—Fibrous silica nanocomposites
Authors: Fihri Aziz , Lazko Jevgenij , Laoutid Fouad , Mariage Jérôme , Passion Julie , Schow Tim , Malajati Yassine , Rastogi Ruchi , Alamri Haleema , Dubois Philippe 
Published: December 2023

AbstractThis paper reports the results of polyethylene (PE) and polypropylene (PP) composites containing 5 and 10 wt.% dendritic fibrous nanosilica (DFNS) synthesized by a hydrothermal process. The objective of this investigation is to provide a better understanding of the relationship between the structure, composition, matrix‐nanofiller interfaces, and the properties of these nanocomposites. These materials have been prepared by twin‐screw extrusion and injection molding. Their structural, thermal, mechanical, rheological, and electrical properties were evaluated, both alone and when combined with an organic compatibilizing agent. Findings have shown that the unique morphology of fibrous silica nanoparticles was preserved and not altered by melt processing, indicating the high thermal and mechanical stability of these fibrous materials. The nanocomposites containing DFNS alone exhibited higher mechanical performances compared to those containing the surface modifier, with no observable effect on their thermal properties. Findings also showed that the interactions between the nanoparticles and polymer may influence the functional properties of the final nanocomposites, and that they are dependent on both the nature of the host polymer along with the presence of the surface modifier agent.Highlights
Well‐defined DFNS were successfully prepared.
PE and PP based nanocomposites were successfully designed by twin‐screw extrusion.
Good interfacial interactions were obtained with PP.
Functional properties of the nanocomposites were influenced by the interfacial adhesion.
A minimum specification dataset for liquid ocular endotamponades: recommendations by a European expert panel
Authors: Ferrara Mariantonia , Steel David HW , Romano Mario R ,   for the European Intraocular Tamponades Study Group, Chandra Aman , Coco-Martin Rosa M , Pastor J Carlos , Ferrara Mariantonia , Januschowski Kai , Rickmann Annekatrin , Pastor-Idoate Salvador , Romano Mario R , Smith Jonathan , Steel David HW , Spitzer Martin S 
Published: December 2023

Abstract
Purpose
To propose a minimum specification dataset to characterize liquid ocular endotamponades (OEs), namely silicone oil (SO), heavy SO (HSO), perfluorodecalin (PFD), and perfluoro-octane (PFO), in terms of physicochemical properties, purity and available evidence of safety, in line with ISO16672:2020.

Methods
An evidence-based consensus using the expert panel technique was conducted. Two facilitators led a committee of 11 European experts. Facilitators prepared a dataset for each compound including the list of specifications relevant for the safety, identified by the group members on the basis of expertise and a comprehensive literature review. Each item was ranked by each member using a 9-point scale from 1 “absolutely to not include” to 9 “absolutely to include” in two rounds followed by discussion. Only items reaching consensus (score ≥ 7 from ≥ 75% of members) were included in the final datasets.

Results
For all OEs, consensus was reached to include manufacturer, density, refractive index, chemical composition, dynamic viscosity, interfacial and surface tension, endotoxins, in vitro cytotoxicity assessment, and any evidence from ex vivo and/or in vivo tests for safety assessment. Additional specifications were added for SO (molecular weight distribution, content of oligosiloxanes with MW ≤ 1000 g/mol, spectral transmittance) and PFD/PFO (% of pure PFD/PFO in the final product, vapor pressure, chemical analyses performed for safety assessment).

Conclusion
The proposed evidence-based minimum specification datasets for SO, HSO, PFD, and PFO have the potential to provide surgeons and health service purchasers with an easily available overview of the most relevant information for the safety assessment of OEs.
Experimental Investigation of Mechanical Properties of Additively Manufactured Fibre-Reinforced Composite Structures for Robotic Applications
Authors: Bisoi Arnav , Tüfekci Mertol , Öztekin Vehbi , Denimal Goy Enora , Salles Loïc 
Published: December 2023

AbstractThis study explores the variation in mechanical properties of additively manufactured composite structures for robotic applications with different infill densities and layer heights using fused deposition modelling (FDM). Glass fibre-reinforced polyamide (GFRP), and carbon fibre-reinforced polyamide (CFRP) filaments are used, and the specimens are printed with 20%, 40%, 60% and 100% infill density lattice structures for tensile and three-point bending tests. These printed samples are examined in the microscope to gain more understanding of the microstructure of the printed composites. To characterise the mechanical properties, a set of tensile and three-point bend tests are conducted on the manufactured composite samples. Test results indicate the variations in tensile strength and Young’s modulus of specimens based on the printing parameters and reveal the tensile and bending behaviour of those printed composite structures against varying infill ratios and reinforcing fibres. The experimental findings are also compared to analytical and empirical modelling approaches. Finally, based on the results, the applications of the additively manufactured structure to the robotic components are presented.