bluuebunny/crossref_metadata_2025_split huggingface dataset:
Planning of Microgrids Coalition Considering Renewable Energy Prediction Based on Machine Learning Algorithm
Authors: Mahmoudabadi Negar Dehghani , Khalaj Mehran , Jafari Davood , Herat Ali Taghizadeh , Ahranjani Parisa Mousavi 
Published: November 2023

Abstract
This paper presents an energy management plan to schedule of different generation resources in a smart distribution system comprised of multi-microgrids in normal and abnormal condition. In this regard, after detecting the main characteristics for a management scheme, a suitable framework is planned and the functions of various management entities in a multi-microgrids system are initiated. The microgrids schedule their generation resources in the first step using a new model based on the framework. In the second step, distribution system operator determines the possible power transmits between the microgrids and uses the remained capacities of microgrids’ resources for supplying the unserved loads in step I. In order to determine the amount of available capacity for renewable energy resources such as solar and wind energy, Extreme Learning Machine (ELM) is used to predict the value of solar radiation and wind power. The proposed plan is implemented on a test system under normal and different abnormal events via realistic case studies.
Critical-sized marginal defects around implants treated with xenografts in rabbits
Authors: Asano Akihisa , Xavier Samuel Porfirio , Silva Erick Ricardo , Morinaga Kenzo , Botticelli Daniele , Nakajima Yasushi , Baba Shunsuke 
Published: November 2023

Abstract
Background: Healing of critical-size defects is a well-known problem that has been challenged in several studies. The aim of the experiment was to evaluate bone formation and osseointegration of implants installed in critical defects of the mandibular body simultaneously grafted with Bio-Oss® or Cerabone®.
Material and methods: Defects, 10 mm wide and 3 mm deep, were prepared at both lateral aspects of the mandible in 12 rabbits. One implant was installed in the center of the defect, and bovine xenografts produced either at low (Bio-Oss®; Low-T) or high (Cerabone®; High-T) temperatures were used to fill the defects. A collagen membrane was placed to cover the sites. Healing was evaluated 10 weeks after surgery.
Results: In both groups, most sites showed optimal healing with closure of the coronal entrance of the defects. However, residual defects occupied by soft tissues and biomaterial particles were observed, even though generally limited to some regions of the defect. Osseointegration of the implant surface in the region of the defect was poor in both groups.
Conclusions: Circumferential marginal critical-size defects around implants filled with bovine xenografts presented regions with a complete healing in both groups. However, the healing was not complete at all regions in most defects; therefore, a complete optimal healing of critical-size marginal defects cannot be predicted.
Evaluation on liquefaction effect of potassium dissolution extraction from low-grade solid potash ore in Qarhan Salt Lake, northern of Tibetan Plateau
Authors: Song Yachao , Hu Han , Ye Chuanyong , Zhao Yuanyi , Ma Lichun , Zhang Juan , Yan Qunxiong , Lin Yuhan 
Published: November 2023

Abstract

China, being the world's largest consumer of potassium fertilizer, faces significant challenges due to limited potassium reserves. Qarhan Salt Lake stands out as a reservoir containing 296 million tons of low-grade solid potash ore (KCl), establishing itself as the premier potassium fertilizer production base in China. The extraction of low-grade solid potash ore via liquefaction technology, leading to the generation of potassium-rich brine, emerges as a pivotal strategy for sustainable potash exploitation in the region. This approach offers a promising solution to mitigate the potassium salt shortage in China. This paper systematically examines the transformation in KCl content of solid potash ore within the Bieletan section of Qarhan Salt Lake before (2007) and after liquefaction (2022). The study employs quantitative assessments to determine liquefaction volume and efficiency. Results reveal that, at a shallow depth of 23.20m, the average KCl content of solid potash ore decreases from 2.15% before liquefaction to 1.00% after liquefaction. This observed decrease of 1.15% (53% reduction) underscores the substantial impact of liquefaction. A total of 136.94 million tons of KCl are dissolved, providing a sustainable resource for approximately 15 years or more. During the initial stages of liquefaction (2007-2008), a rapid decline in the KCl content of solid potash ore is noted, with liquefaction efficiency significantly influenced by the positioning of the brine mining channel. As liquefaction progresses, efficiency diminishes, although the overall efficiency surpasses that of the Huobuxun section at the eastern extremity of Qarhan Salt Lake. This study holds significant implications for refining the solid potash liquefaction mining strategy in Qarhan Salt Lake, providing valuable guidance for future optimization efforts.
Contrast Enema for neonatal distal bowel obstruction: The diagnostic and pathological yield
Authors: -Women’s Mark Fitzgerald , Taranath Ajay , Goh Day Way 
Published: November 2023

Abstract

Purpose:
Neonatal distal bowel obstruction (DBO) can present a diagnostic challenge [1, 2] As different aetiologies have similar clinical manifestations with not all surgical intervention [2, 3]. Contrast enemas (CE) can help differentiate the aetiology avoiding the need for surgery [2–4]. We reviewed 20years of CE to evaluate their diagnostic and pathological yield in neonatal DBO.
Method:
CE for DBO undertaken in neonate between 2001 and 2021 were reviewed with studies. Medical records for 98 patients (109 CE) were accessed to review the results, the definitive diagnosis, birth weight, gestation and age at time of CE.
Results:
Meconium plug syndrome (MPS) (n = 32) was the commonest radiological diagnosis followed by bowel atresia (n = 20), Hirschsprung’s disease (HD) (11) and meconium ileus (10). Of the CE 16% were normal, 14% were non diagnostic. One third of patients with a radiological diagnosis of MPS had a eventual definitive diagnosis that required surgical intervention, either HD, meconium ileus or SBO. The definitive diagnosis was most commonly MPS (n = 29), followed by HD (21) and bowel atresia (16). There were no statistically significant differences in demographics among the definitive diagnoses.
Conclusion:
CE in neonatal DBO has a high diagnostic and pathological yield aiding in determining which patients require surgery.

Level of Evidence:

Level IV
Heart rate variability as a predictor of intraoperative autonomic nervous system homeostasis
Authors: Keim Ole C. , Bolwin Lennart , Feldmann Robert E. , Thiel Manfred , Benrath Justus 
Published: November 2023

Abstract
Purpose
The aim of the proof-of-concept study is to investigate the level of concordance between the heart rate variability (HRV), the EEG-based Narcotrend Index as a surrogate marker for the depth of anesthesia, and the minimal alveolar concentration (MAC) of the inhalation anesthetic sevoflurane across the entire course of a surgical procedure.
Methods
This non-blinded cross-sectional study recorded intraoperative HRV, Narcotrend Index, and MAC in 31 male patients during radical prostatectomy using the Da-Vinci robotic-assisted surgical system at Mannheim University Medical Center. The degree of concordance was calculated using repeated measures correlation with the R package (rmcorr) and presented using the rmcorr coefficient (rrm).
Results
The Narcotrend Index correlates significantly across all measures with the time-dependent parameter of HRV, the standard deviation of the means of RR intervals (SDNN) (rrm = 0.2; p < 0.001), the frequency-dependent parameters low frequency (LF) (rrm = 0.09; p = 0.04) and the low frequency/high frequency ratio (LF/HF ratio) (rrm = 0.11; p = 0.002). MAC correlated significantly negatively with the time-dependent parameter of heart rate variability, SDNN (rrm = -0.28; p < 0.001), the frequency-dependent parameter LF (rrm = -0.06; p < 0.001) and the LF/HF ratio (rrm = -0.18; p < 0.001) and the Narcotrend Index (rrm = -0.49; p < 0.001) across all measures.
Conclusion
HRV mirrors the trend of the Narcotrend Index used to monitor depth of anesthesia and the inhibitory influence of the anesthetic sevoflurane on the autonomic nervous system. Therefore, HRV can provide essential information about the homeostasis of the autonomic nervous system during general anesthesia.
Trial registration number:
DRKS00024696, March 9th, 2021
Comparison of the effect of dexamethasone, ketoprofen and cold Compress on Postoperative quality of life following impacted lower third molar surgery: A randomized clinical trial
Authors: Suleiman Ibrahim Kayode , James Olutayo , Olasoji Hector Oladapo 
Published: November 2023

Abstract
Objectives: To evaluate and compare the effect of dexamethasone, ketoprofen and cold compress on the quality of life (QoL) following surgical removal of impacted lower third molar (ILTM).
Materials and Methods: Eligible patients requiring ILTM extraction with modified Pederson difficulty index score of 5-6 were recruited. The patients were randomly allocated into Group A, B and C. The group A and C patients received pre-operatively, 100mg of ketoprofen and 8mg of dexamethasone per-oral respectively. Subjects in group B applied a pre-standardized ice pack over the angle of the mandible for 6 hours postoperatively. The QoL questionnaire was administered on postoperative day 1, 2 and 7.
Results: In total, seventy-eight subjects completed the study: 46 (59%) were male and had a mean age of 27.8 ± 4.9 years. The groups were similar sociodemographically. The overall QoL and appearance domain score was significantly better in patients on oral dexamethasonein postoperative day 1 compared to other groups.
Conclusions: Oral dexamethasone demonstrates better improvement in postoperative QoL and appearance on day 1 following ILTM surgery compared to ice packs and ketoprofen. Although ice packs are readily available, can be used repeatedly and are a low-cost option, more research is necessitated to determine its optimum therapeutic use in outpatient setting that will produce a result superior to a single dose of oral dexamethasone.
Clinical Relevance: Oral dexamethasone is superior to ice pack compress and ketoprofen in improving the postoperative QoL in ILTM surgery.
Physical inactivity during pregnancy: its associations with socio-demographic background and mental health
Authors: Sándor Nikolett Gabriella , Boros Julianna , Kopcsó Krisztina , Lábadi Beatrix 
Published: November 2023

Abstract

Background: Exercise during pregnancy is known to have positive effects on both maternal and foetus health. Despite international recommendations advocating regular exercise for healthy pregnant women survey data indicate that physical activity decreases during pregnancy, particularly in the third trimester.
This study aims to assess the physical inactivity levels of pregnant women in Hungary in a representative sample and to explore the association between physical inactivity, socio-demographic characteristics, and mental health.
Method: Utilizing data from the Cohort'18 Hungarian Birth Cohort Study during pregnancy, our analysis encompasses 6121 pregnant women. The survey, administered by local health visitors, assessed the amount of physical activity, such as sports, cycling and walking, done in one week before pregnancy and in the third trimester of pregnancy. Mental health was evaluated through self-administered paper-pencil questionnaires, measuring depression (CES-D-8) and anxiety (GAD-2) questionnaires.
Results: The inactivity rate during pregnancy was 70% for walking, 92% for cycling and 90% for sports. Inactivity increased across all forms of physical activity during pregnancy. Socio-demographic determinants influencing physical inactivity varied for different activities during pregnancy. Walking and doing sport were significantly associated with equivalent income quintiles, educational attainment, parity, and the population of the settlement. For cycling, educational attainment, employment status and the population of the settlement held significant predictive power.
Examined socio-demographic variables explained 3,5-4,7% of the variance in walking, 3,3-7,8% in cycling, and 7-14% in doing sport during pregnancy. Mental status significantly associated only with doing sport during pregnancy.
Conclusions: Our study provides insight into the high rates of third trimester physical inactivity among pregnant women in Hungary, especially for vigorous activity, using representative data. The findings underscore the importance of raising awareness about physical activity in antenatal care, particularly targeting at-risk population. Health education in the antenatal care process should be expanded to emphasize the crucial role of physical activity during pregnancy.
Impact of Cannabis Legalization on Hospitalizations in Alberta: Interrupted Time Series Analysis by Age and Sex
Authors: Kim Chungah , Bai Yihong , Allin Sara , Kirst Maritt , O’Campo Patricia , Ienciu Kristine , Xia Xiaoyang , MacMaster Frank , Rittenbach Katherine , Chum Antony 
Published: November 2023

Abstract
Using population-wide health administrative data in Alberta, Canada (10/2015-05/2021, n = 3,493,864), we find that cannabis legalisation was not associated with significant increases in cannabis-related hospitalizations. Hospitalization rates were higher in young adults (18–24) compared to those 25+, and the introduction of edibles was associated with insignificant immediate increases of 23% and 18% among younger women and men respectively. Comparison with patterns in Ontario from in a prior study finds that cannabis legalisation led to increased hospitalization in Ontario but not Alberta. The findings highlight the need for targeted screening and interventions for young adults.
Trends in the Ophthalmic Workforce and Eye Care Infrastructure in South India: Cross-Sectional Questionnaire Study
Authors: Pallerla Srinivasa R , Pallerla Madhurima R , Krishnaiah Sannapaneni 
Published: November 2023

Background
This study is part of broad-based research to determine the impact of blindness control activities in general and with special reference to the Andhra Pradesh Right to Sight Society (APRTSS) activities in the southern Indian states of Andhra Pradesh and Telangana. As part of the global “VISION 2020: The Right to Sight” initiative, the APRTSS was established in the undivided state of Andhra Pradesh in 2002. Since then, the APRTSS has been actively implementing the strategies of VISION 2020 to reduce visual impairment and blindness in the state.

Objective
The availability and distribution of the eye care workforce are essential to reach the goals of VISION 2020: The Right to Sight, the global initiative to eliminate avoidable blindness. This study assessed the trends in the availability and distribution of eye health professionals and eye care infrastructure in 2 southern Indian states: Andhra Pradesh and Telangana.

Methods
This cross-sectional study used a pretested questionnaire to gather data for the year from 2012 to 2013. Data for 2002 to 2003 were collected from available historical records. The questionnaires were pretested in a pilot study conducted before the main survey. Pretested questionnaires were administered to all eye care professionals—ophthalmologists (n=1712) and midlevel ophthalmic personnel (MLOP; n=1250)—eye care facilities with ≥10 inpatient beds or performing ≥100 cataract surgeries per annum (n=640), local nongovernmental eye care organizations (n=182), and international eye care organizations (n=10). Data were collected for 2 different time periods: the baseline year of 2002 to 2003 and the target year of 2012 to 2013. Data analysis was conducted using SPSS version 19.0.

Results
The response rates were 81.1% (519/640) for eye care facilities, 96.1% (1645/1712) for ophthalmologists, and 67.6% (845/1250) for MLOP. From 2002-2003 to 2012-2013, there has been an increase in eye care facilities, from 234 to 519 (121.8%); ophthalmologists, from 935 to 1712 (83.1%); and MLOP, from 767 to 1250 (63%). The ophthalmologist:population ratio improved from 1:88,260 in 2002-2003 to 1:51,468 in 2012-2013. The MLOP:population ratio improved from 1:168,283 in 2002-2003 to 1:138,117 in 2012-2013 but still falls short of the ideal number.

Conclusions
Both southern Indian states are able to meet the requirements for ophthalmologists and eyecare infrastructure as per the goals of VISION 2020. However, the number of MLOP falls short of the ideal ratio for the population. This study has some limitations. For example, most of the data collected through questionnaires were based on self-report, which might introduce bias due to memory recall or over or under-reporting of certain information. However, this was addressed by cross-checking the collected data with information from supplementary sources.
Dazhu Hongjingtian Injection for Ischemic Stroke: Protocol for a Prospective, Multicenter Observational Study
Authors: Che Qianzi , Song Tian , Liang Ning , Guo Jing , Chen Zhao , Liu Xiaoyu , Yang Lu , Jiang Yin , Wang Yanping , Shi Nannan 
Published: November 2023

Background
Although results from in vitro studies and small randomized controlled trials have shown positive effects of Dazhu hongjingtian injection (DZHJTI) on acute ischemic stroke (AIS), their generalizability to routine clinical practice remains to be established.

Objective
The primary aim of this study is to evaluate the effectiveness of DZHJTI treatment for AIS with regard to changes in the stroke-related neurological deficit from baseline to outpatient follow-up, mortality, subsequent vascular events, disability, and traditional Chinese medicine syndrome in real-world clinical settings. By monitoring for adverse events or significant changes in vital signs and laboratory parameters, we also aim to assess the safety of DZHJTI.

Methods
This prospective, multicenter cohort study plans to enroll 2000 patients with AIS within 14 days of symptom onset from 30 hospitals across China. Eligible patients will be followed up for 6 months after initiating medication treatments. The primary outcome will be the change in the National Institute of Health Stroke Scale score from baseline to outpatient follow-up. The secondary outcomes include overall mortality, stroke recurrence, new-onset major vascular events, global disability, and improvement of traditional Chinese medicine syndrome in 6 months. Adverse events or clinically significant changes in vital signs and laboratory parameters, regardless of the severity, will be recorded during the trial to assess the safety of DZHJTI. An augmented inverse propensity weighted estimator will be used to reduce variability and improve accuracy in average treatment effects estimation.

Results
The clinical trial registration was approved in October 2022, and the recruitment and enrollment of participants started in November 2022. The study’s outcomes are expected to be published in 2025 in reputable, peer-reviewed health-related research journals.

Conclusions
This real-world cohort study is the first to assess the effectiveness and safety of DZHJTI in treating AIS. It may provide additional clinical evidence, including the duration of response, long-term drug effectiveness, and subgroup efficacy data. The study results will be valuable for clinicians and patients seeking optimal treatment for AIS and could lead to better use of DZHJTI and improved patient outcomes.

Trial Registration
ITMCTR ITMCTR2022000005; http://tinyurl.com/554ns8m5

International Registered Report Identifier (IRRID)
DERR1-10.2196/52447
COMPARATIVE STUDY BETWEEN TRAMADOL AND KETOROLAC IN POST-OPERATIVE ANALGESIA IN CHOLECYSTECTOMY IN A TERTIARY CARE HOSPITAL
Authors: KAUSHIK SHOBHIT , RAI JAYANT , HARSHWARDHAN  , KAUSHIK SHIPRA 
Published: November 2023

Objective: The aim of the study is to compare the analgesic efficacy of Tramadol (TRA) to that of Ketorolac (KET) administered I. V. and at fixed times over 24 h after open cholecystectomy.
Methods: The study enrolled 50 ASA I and II patients between 30-60 y of age of either sex undergoing open cholecystectomy. Two treatment groups were formed with 25 patients in each group which received Tramadol and Ketorolac. The pain score was measured using Visual Analog Scale (VAS).
Results: Statistical analysis was done by t-test, in which onset of action, duration of action, number of rescue analgesics required and VAS score was compared.
Conclusion: Tramadol is better analgesic than Ketorolac.
Hubungan Karakteristik Keluarga terhadap Frekuensi Kekambuhan pada Pasien dengan Skizofrenia di Rumah Sakit Jiwa Provinsi Bali
Authors: Prabhawidyaswari Ni Made Cintia , Yanti Ni Putu Eka , Saraswati Wayan Sarah , Darmawan I Putu Edi , Puspitasari Ni Putu Rina , Suari Desak Ayu Wulan Mas , Parayoga Dwipayana I Made 
Published: November 2023

Skizofrenia termasuk dalam gangguan jiwa berat yang ditandai dengan terganggunya kemampuan menilai realitas, bersifat kronis, sering kambuh atau berulang yang memerlukan pengobatan jangka panjang. Kekambuhan pada skizofrenia dapat dipengaruhi oleh berbagai faktor, salah satunya karakteristik keluarga. Penelitian ini bertujuan untuk mengetahui hubungan karakteristik keluarga (tingkat pendidikan, pekerjaan dan penghasilan) terhadap frekuensi kekambuhan pada pasien dengan skizofrenia di Rumah Sakit Jiwa Provinsi Bali. Penelitian ini menggunakan rancangan crosssectional. Sampel terdiri dari 35 responden keluarga pasien dengan skizofrenia yang dipilih dengan cara purposive sampling. Pengumpulan data menggunakan kuesioner karakteristik keluarga dan rekam medis pasien skizofrenia yang mengalami kekambuhan. Hasil penelitian menggunkan uji statistik Spearman Rank, didapatkan hasil bahwa karakteristik keluarga tingkat pendidikan (p value = 0.01), pekerjaan (p value = 0.03), dan penghasilan (p value = 0.03) memiliki hubungan yang signifikan (p value 0.05) terhadap frekuensi kekambuhan pasien dengan skizofrenia. Terdapat hubungan korelatif kuat antara karakteristik keluarga dengan frekuensi kekambuhan pasien skizofrenia dengan nilai koefisien korelasi tingkat pendidikan -0.556, pekerjaan 0.511, dan penghasilan -0.541. Berdasarkan hasil penelitian di atas disarankan kepada keluarga agar mampu mengoptimalkan peran dan tugas keluarga melalui pemberian edukasi yang berkelanjutan oleh tenaga kesehatan kepada keluarga pasien skizofrenia dalam perawatan pasien di rumah.