bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comparative Analysis of Alkaline Phosphatase Levels in Gingival Crevicular Fluid: A Three-Time Point Study Comparing Clear Aligners and Fixed Orthodontic Appliances
Authors: Pisarla Manish , Rathod Ravi , Kalpakuri Rajivi , Kumar P Anoop , Nishanth B , Goje Akshay , Kala Tejaswi 
Published: January 2025

ABSTRACT

Aim:
To evaluate the alkaline phosphatase level in gingival crevicular fluid (GCF) at three time points using clear aligners and fixed orthodontic appliances.

Materials and Methods:
A prospective randomized controlled trial was conducted in a tertiary care hospital to treat patients with 4–6 mm crowding in their upper front teeth. The study involved 20 patients, with 10 assigned to each group. Eligible patients had fully erupted permanent teeth, moderate crowding, and excellent dental health. The study lasted for 14 days and involved thermoplastic trays, Gemini metal brackets, and micropipettes.

Results:
This clinical study analyzed 20 participants, comprising 11 females and 9 males, with an average age of 25.23 ± 3.56 years. The data showed no significant differences in alkaline phosphatase (ALP) levels between the fixed orthodontic appliance and clear aligner groups. However, there was a notable increase in ALP levels in the crevicular fluid across both groups. The clear aligner group had significantly higher ALP levels at time points T1 and T2.

Conclusion:
Clear aligners may facilitate faster tooth movement due to elevated crevicular ALP levels, although robust scientific evidence is limited. The light force exerted by clear aligners may not significantly impact the overall rate of tooth movement.
Antioxidant Studies of Ayurvedic Medicine, Dhanwanthararishtam
Authors: Devi Barri Indira , Kalaivannan J , Jones Sumathi , Janaki CS , Sheriff Dhastagir , Prabhu K , Balakrishnan Deepalakkshmi , Selvam Angelin David 
Published: January 2025

ABSTRACT

Background:
Dhanwanthararishtam is a classical Ayurvedic medicine, primarily used for postnatal care and rejuvenation.

Aim:
The present study evaluates the antioxidant properties of the Ayurvedic medicine Dhanwanthararishtam, traditionally used for postnatal care to rejuvenate and strengthen the mother.

Methods:
ABTS, DPPH, and FRAP, were the antibiotic assays carried out following standard protocols.

Results:
Among these assays, Dhanwanthararishtam exhibited exceptional results at very low concentrations in the FRAP assay, while the ABTS and DPPH assays showed moderate antioxidant activities.

Conclusion:
These findings clearly demonstrate the antioxidant potential of Dhanwanthararishtam, supporting its medicinal efficacy.
Effect of Passive Immunotherapeutics (IgY) on S. Mutans in Caries Active Children 8-11 Years of Age
Authors: Panigrahi Antarmayee , Pattanaik Snigdha , Mohammad Noorjahan , Sahoo Subhrajeet N. , Patnaik Swati , Sarangi Debarchita 
Published: January 2025

ABSTRACT

Introduction:
Dental caries is a multifactorial disease caused by combined effect of host, environment, and microorganism. Mutans Streptococci (MS) is the main microorganism in causing and progression of dental caries. Advances in science and technology led to attempt in managing dental caries by targeting its initiation and delaying its progress. Immunoglobulin Y has proven efficacy in reducing the colonisation of S. Mutans by affecting the adhesion.

Aim:
Thus the present study was undertaken to evaluate the effect of passive immunisation on S.Mutans levels in caries active children aged 8-11 yrs of age.

Materials and methods:
Total of 50 children were randomly divided into IgY mouthspray (Test Group) and 0.9% Saline (Control group). Saliva sample were collected and subjected to microbial examination using MSB agar at the end of 30 days of study period.

Results:
Within the limitations, it can be concluded that IgY mouthspray significantly reduces the adhesion and growth of the causative agent S.Mutans in caries active children.

Conclusion:
Use of passive immunisation significantly reduces the bacterial overload and thus decreasing the dental caries in high risk children.
Comparative Evaluation of the Flap and Flapless Techniques for the Extraction of Impacted Third Molars Using a Split-Mouth Prospective Randomized Control Research
Authors: Karpe Tanveer , Qureshi Mohammed Y. , Shaik Sheraz B. , Nasyam Fazil A. , Kavya Pinnamaneni , Harika Thatavarthi S. 
Published: January 2025

ABSTRACT

Aim:
Comparative evaluation of the flap and flapless techniques for the extraction of impacted third molars using a split-mouth prospective randomized control research.

Material and Methods:
The research comprised 120 healthy individuals. Every patient having surgery was separated into two locations and then randomly allocated to two groups: Group I (control, n = 60) had surgical extraction of the lower third molar by elevating a buccal flap, and Group II (study group, n = 60) had surgical extraction of the lower third molar without the need to raise a buccal flap.

Results:
The flap group had a preoperative swelling measurement of 12.4 ± 1.2 cm. By the second day after the surgery, the edema grew to 14.6 ± 1.5 cm and gradually reduced to 13.0 ± 1.3 cm by the seventh day after the surgery. The preoperative edema in the flapless group was assessed at 12.5 ± 1.3 cm. By the second day after the operation, the swelling measured 13.2 ± 1.4 cm, and it dropped to 12.7 ± 1.2 cm by the seventh day after the operation. The evaluation of pain levels was done using a visual analog scale (VAS). By the second day after the operation, the group with flaps reported a pain score of 6.5 ± 1.1, which then declined to 4.3 ± 0.9 by the seventh day. The pain score in the group without flaps was 5.1 ± 1.0 on the second day after surgery and dropped to 3.2 ± 0.8 on the seventh day. Patients had a considerable reduction in discomfort when the flapless approach was used on both the second and seventh days after the surgery. The pocket depth was assessed by using a calibrated periodontal probe on the distal surface of the second molar. At the 1-month postoperative milestone, the flap group exhibited a pocket depth of 3.4 ± 0.5 mm, which marginally decreased to 3.2 ± 0.4 mm by the second month. In the group without flaps, the depth of the pocket was measured to be 3.1 ± 0.4 mm after 1 month and 3.0 ± 0.3 mm after 2 months.

Conclusion:
The flapless approach led to reduced postoperative edema, discomfort, and trismus as well as a shorter surgical time. Despite small variations in pocket depth, the flapless method resulted in a more favorable overall postoperative recovery.
Effects of Music Therapy and Deep Relaxation Techniques for Reducing Perioperative Anxiety in Patients Undergoing Spinal Surgeries: A Randomized Controlled Trial
Authors: Muniyandi Anjali Devi , Pradhan Rekha , Prabhakar Hemanshu , Phalak Manoj , Suthar Hansaram , Bhavsar Nikhil , Plaha Paramjit Kaur , Naganandini Raju 
Published: January 2025

ABSTRACT

Background:
This study aimed to evaluate the effectiveness of music therapy and deep relaxation technique (DRT) in reducing perioperative anxiety, a challenging occurrence that can negatively impact treatment results and patient distress, and mitigate the adverse effects of anxiety-reducing drugs.

Methodology:
The study involved 90 patients, including 28 using DRT, 31 using music therapy, and 31 without intervention. The Hamilton Anxiety Rating Scale was employed to measure perioperative anxiety levels. DRT, music therapy, and routine interventions were used.

Results:
The study found a significant difference in pretest and posttest perioperative anxiety scores between the DRT and music therapy groups. Notably, there was a significant difference between the music therapy and control groups and a highly significant difference between the control and DRT groups.

Conclusion:
The study found that both music therapy and DRT can effectively reduce perioperative anxiety in patients undergoing spinal surgeries.
Evaluation of miR-146a as a potential biomarker for diagnosis of cardiotoxicity induced by chemotherapy in patients with breast cancer
Authors: Zare Nasrin , Dana Nasim , Mosayebi Azam , Vaseghi Golnaz , Javanmard Shaghayegh Haghjooy 
Published: January 2025

Background:
Cardiotoxicity from chemotherapy may result in cardiomyopathy and heart failure. Clinicians can use the evaluation of cardiotoxicity-specific biomarkers, such as microRNA, as a tool for the early detection of cardiotoxicity. The study’s objective was to assess miR-146a levels as a potential biomarker for the detection of cardiotoxicity brought on by chemotherapy in patients with breast cancer.

Materials and Methods:
Using quantitative reverse transcription-polymerase chain reaction, the levels of miR-146a were assessed in the blood of 37 breast cancer patients receiving anthracyclines without cardiotoxicity and 33 breast cancer patients experiencing cardiotoxicity brought on by chemotherapy after chemotherapy. Left ventricular ejection fraction (LVEF) ≥50% was used to define heart failure by echocardiography.

Results:
MiR-146a did not show any significant difference in expression between these two study groups (P = 0.48, t-test). The expression level of miR-146a was not significantly associated with LVEF, age, and body mass index (P > 0.05), according to Pearson correlation.

Conclusion:
MiR-146a may be a diagnostic or prognostic biomarker for cardiotoxicity brought on by chemotherapy, even though there was no discernible difference in the expression level of miR-146a between the control group and the breast cancer patients who were experiencing this side effect of chemotherapy. Therefore, miR-146a expression needs to be examined in a sizable cohort of breast cancer patients who are experiencing cardiotoxicity brought on by chemotherapy.
Constructing skew left braces whose additive group has trivial centre
Authors: Ballester-Bolinches Adolfo , Esteban-Romero Ramón , Jiménez-Seral Paz , Pérez-Calabuig Vicent 
Published: January 2025

Abstract
A complete description of all possible multiplicative groups of finite skew left braces whose additive group has trivial centre is given. As a consequence, some earlier results of Tsang can be improved and an answer to an open question set by Tsang at Ischia Group Theory 2024 Conference is provided.
Sexualidade, gravidez e IST's na adolescência
Authors: Serafim Renata Moraes , Barbosa Manoel Augusto Polastreli 
Published: January 2025

O objetivo deste trabalho foi analisar a relação entre sexualidade, gravidez e IST’s na adolescência na perspectiva de alunos do Ensino de Jovens e Adultos. Trata-se de um estudo qualitativo, exploratório, descritivo. Participaram da pesquisa alunos do sexo masculino e feminino, maiores de dezoito anos. O desenvolvimento da pesquisa aconteceu por meio do desenvolvimento de uma Sequência de Ensino Investigativo (SEI) proposta por Carvalho (2013). Os instrumentos utilizados para obtenção de resultados foram os aplicativos: Padlet, Mentimenter, Google Formulário e Google Meet. Os procedimentos foram divididos em quatro etapas: caixa de curiosidades (Padlet), nuvem de palavras (Mentimenter), estudo de caso (Google Formulário) e roda de conversa com os sujeitos de pesquisa (Google Meet). Os resultados obtidos foram positivos, podendo concluir que para a maior parte dos alunos participantes, a temática sexualidade está relacionada a sexo e a amor. As opiniões sobre o estudo de caso hipotético foram bastante divergentes ao tema do projeto, pois a maioria dos participantes possuem uma idade mais avançada. Espera-se que os dados dessa pesquisa possam servir para embasar futuras pesquisas voltadas para o público da Educação de Jovens e Adultos.
Percepções de bacharelandos/as em Química sobre Divulgação Científica
Authors: Lopes da Silva Caroline , Monteiro Rigue Fernanda 
Published: January 2025

O estudo visa realizar um levantamento das percepções de futuros/as bacharéis/bacharelas em Química sobre Divulgação Científica (DC) e argumentar, com fundamentação teórica, acerca dos achados. Para tanto, por meio de uma investigação qualitativa, do tipo estudo de caso, utilizou-se de um instrumento formulário online, em que as respostas foram analisadas por meio de Análise de Conteúdo. A partir das análises realizadas destacam-se os desafios e limitações da DC como barreiras e déficit de estratégias dos/as cientistas para aproximação com a linguagem de públicos não especializados. Assim como sua capacidade de desempenhar um papel transformador, pois, não só promove a popularização da ciência, mas também fortalece a democracia, capacitando os/as cidadãos/ãs a tomarem decisões fundamentadas cientificamente no cotidiano. Portanto, a DC precisa ser encarada como uma tarefa indispensável na formação universitária, considerando seu potencial protagonismo na construção de uma sociedade cada vez mais engajada e participativa.
ANALISIS DETERMINAN FRAUD DALAM DISTRIBUSI BANTUAN SOSIAL: PERSPEKTIF FRAUD TRIANGLE
Authors: Sari Fangela Myas , Elshifa Aria , Aria Mulyapradana  
Published: January 2025

The purpose of the study was to determine the effect of financial misstatement and the fraud triangle on social assistance fraud. The respondents of the study were 30 employees of the Batang Regency Social Service. Purposive sampling was used in this study. The analysis technique used convergent validity test, reliability test, discriminant test, structural model evaluation, and hypothesis testing with path coefficients. The results of the hypothesis testing analysis showed that the financial misstatement and opportunity variables did not have a significant effect on social assistance fraud at the Pekalongan Regency Social Service. The pressure and rationalization variables had a significant effect on social assistance fraud at the Batang Regency Social Service.

Keywords: Financial misrepresentation, Fraud triangle, Social assistance
Human AI– Collaboration Platform
Authors:   Professor ,Department of Computer Science, Dr.N.G.P Arts and Science College, India, Deepa  Dr.N. 
Published: January 2025

Human-AI collaboration (HAIC) is emerging as a pivotal approach in various sectors, enhancing productivity, creativity, and decision-making. This journal explores the current state of HAIC, its future prospects, and ethical considerations, emphasizing the importance of quality in collaboration. Quality in HAIC encompasses the effectiveness, reliability, and ethical implications of AI systems in collaborative environments. As organizations increasingly integrate AI into their workflows, understanding the dynamics of HAIC becomes essential for maximizing benefits while addressing challenges. This exploration aims to provide insights into how human-AI collaboration can be optimized for better outcomes in diverse fields.

Keywords: Human-AI collaboration, AI ethics, productivity, quality, decision-making, workforce transformation.
Повышение качества дополнительного образования через системное внедрение технологии творческой проектной деятельности
Authors: Исаханова О.Г. 
Published: January 2025

В статье рассматривается проблема недостаточной теоретико-методологической и практической разработанности способов развития творческого потенциала одарённых и талантливых обучающихся через творческую проектную деятельность в системе дополнительного образования. Технология творческой проектной деятельности рассматривается как вид образовательной технологии, обеспечивающей создание продуктов, обладающих новизной и общественной значимостью. Представлена авторская модель системного внедрения технологии творческой проектной деятельности, включающей нормативно-правовой, ресурсно-методический, операциональный и мониторинговый компоненты. Модель основана на деятельностном, творческом и интегративном подходах и направлена на обеспечение нового качества дополнительного образования, ориентированного на поддержку и развитие творческого потенциала обучающихся. Предложен комплекс педагогических условий для эффективной реализации модели, включающий: методическое сопровождение деятельности педагогов, организацию совместного творчества педагогов, обучающихся и их родителей, а также формирование интегративных знаний и умений посредством межпредметных заданий.
The article considers the problem of insufficient theoretical, methodological and practical development of methods for developing the creative potential of gifted and talented students through creative project activities in the system of additional education. The technology of creative project activities is considered as a type of educational technology that ensures the creation of products that are novel and of social significance. The author's model of systemic implementation of the technology of creative project activities is presented, including regulatory, resource-methodological, operational and monitoring components. The model is based on activity-based, creative and integrative approaches and is aimed at ensuring a new quality of additional education focused on supporting and developing the creative potential of students. A set of pedagogical conditions for the effective implementation of the model is proposed, including: methodological support for the activities of teachers, organization of joint creativity of teachers, students and their parents, as well as the formation of integrative knowledge and skills through interdisciplinary tasks.
Индивидуальный маршрут внеучебной деятельности как фактор формирования национального характера современного школьника
Authors: Николаенко Г.С. 
Published: January 2025

Рассматривается проблема разработки и реализации индивидуальных маршрутов внеучебной деятельности, способствующих формированию национального характера обучающихся в условиях образовательной организации. Индивидуальный маршрут внеучебной деятельности определяется как персонально-событийный путь реализации личностного потенциала обучающегося в процессе внеучебной деятельности в школе в соответствии с его личными предпочтениями и интересами. Предложена авторская модель, которая построена на индивидуальном, системном и деятельностном подходах и включает координирующий, инструментально-методический, программно-информационный, практический и диагностико-оценочный компоненты. Модель характеризуется управляемостью, интерактивностью, универсальностью и при реализации требует учёта принципов стимулирования, эмпатийного взаимодействия, гибкости, оптимальности и согласованности. Наиболее эффективно построенная модель функционирует при обеспечении следующих педагогических условий: учёт индивидуального опыта деятельности, единство субъектов в процессе воспитания ребёнка, учёт интересов и ценностных ориентаций, обеспечение гибкости во взаимодействии с семьёй обучающегося.
The article considers the problem of development and implementation of individual routes of extracurricular activities that contribute to the formation of the national character of students in the context of an educational organization. An individual route of extracurricular activities is defined as a personal and event-based way of realizing the personal potential of a student in the process of extracurricular activities at school in accordance with his personal preferences and interests. The author's model is proposed, which is built on an individual, systemic and activity-based approach and includes a coordinating, instrumental and methodological, program and information, practical and diagnostic and assessment components. The model is characterized by controllability, interactivity, universality and, when implemented, requires considering the principles of stimulation, empathic interaction, flexibility, optimality and consistency. The most effectively constructed model functions when the following pedagogical conditions are ensured: considering individual experience of activity, unity of subjects in the process of raising a child, considering interests and value orientations, ensuring flexibility in interaction with the student's family.
Plotinos’ta Bilinç Kavramı
Authors: Güler Sema 
Published: January 2025

Knowing and understanding existence has always existed in the history of philosophy. One of the philosophies that try to explain and understand existence is Neoplatonism, which is the name of rebirth in Hellenistic philosophy. The founder of Neoplatonism is Plotinus. While explaining existence, Plotinus describes it with a cyclical movement from top to bottom and bottom to top. Consciousness also undertakes the task of understanding this cyclical movement. Consciousness is the state of awareness that helps humans understand their own essence and reveal the true essence of beings in the universe. To understand how this awareness occurs, we need to know Plotinus’ system, the overflow theory. The knowledge of the existence in the universe and the true essence of man is hidden in the One, the highest level of existence. One cannot remain in this secret and creates Nous that is close to its own essence. With Nous becoming aware of itself, the third stage of emanation, Spirit, occurs. Again, by turning to the One and contemplating it, the same Nous takes the forms of beings into its own essence. The Spirit formed by Nous is also in a lower position due to its distance from the One. It also maintains its connection with Bir through Nous. The soul returns to Nous and copies the images in Nous into its own essence and transfers them to the substances in the universe. The substances that take the forms receive a light illumination, even if it is less than One. Those who are deprived of this enlightenment continue to remain in darkness in the universe. The substance is bad because it receives little light. In order to understand these events in the universe, the consciousness attached to us through our Spirit becomes important. Our consciousness is an inner experience that gives us the awareness of who we are and enlightens us. With this inner experience, man can understand his place in the universe, his relationship with the universe, and his bond with his Creator. In order to have his own inner experience, his consciousness first pushes him to get rid of his own body’s desires and desires, which always limit people. If a person manages to get rid of these, he feels a lightness and liberation in his soul. The consciousness whose soul is lighter and freer establishes the bond between itself and its creator more easily. For Plotinus, this is watching the One.
* This study is extracted from my master thesis entitled “Plotinos’un Mistisizmi”, supervised by Professor Doctor Sema Önal (Master’s Dissertation KırıkklaeUniversity, Kırıkkale, Turkey 2018).
Elektromedis dalam Pengelolaan Peralatan Elektromedik untuk Pelayanan Kesehatan
Authors: Kridoyono Agung , Hartono Elvianto Dwi , Hardiansyah Bagus , Yunanda Anton Breva , Shidqon Mochamad , Yuwono Istantyo 
Published: January 2025

This article about community service activities discusses the transformation of the electromedical profession as a response to technological developments in the management of electromedical equipment with the aim of improving the quality of health services. This transformation includes changes in the roles, skills and responsibilities of electromedical professionals to adapt and optimize increasingly complex electromedical equipment. The results of this workshop show that the transformation of the electromedical profession has a positive impact on the management of electromedical equipment and the quality of health services. Electromedical professionals involved in this transformation experience increased competency and effectiveness in caring for, maintaining, and repairing electromedical equipment. Apart from that, the application of the latest technology also allows for more efficient monitoring and management of electromedical equipment.

Keywords: Transformation of the electromedical profession, electromedical maintenance, electromedical monitoring