bluuebunny/crossref_metadata_2025_split huggingface dataset:
Eccentric Cycling Is an Alternative to Nordic Hamstring Exercise to Increase the Neuromuscular Function of Knee Flexors in Untrained Men
Authors: Valdes Omar , Inzulza Sixto , Collao Nicolas , Garcia-Vicencio Sebastián , Tufano James J. , Earp Jacob , Venegas Mauricio , Peñailillo Luis 
Published: October 2023

Abstract
Valdes, O, Inzulza, S, Collao, N, Garcia-Vicencio, S, Tufano, JJ, Earp, J, Venegas, M, and Peñailillo, L. Eccentric cycling is an alternative to Nordic hamstring exercise to increase the neuromuscular function of knee flexors in untrained men. J Strength Cond Res 37(11): 2158–2166, 2023—Nordic hamstring exercise (NHE) has been proposed to reduce knee flexor (KF) injuries. However, submaximal alternatives to NHE are necessary for the clinical or weaker population. The aim of this study was to compare the effects of Nordic hamstring training (NHT) and eccentric cycling (ECC) training on the neuromuscular function of the KF. Twenty healthy men (27.7 ± 3.5 years) were randomly assigned into 2 groups that performed 10 training sessions (2–3 sessions·week−1) of either NHT (n = 10) or ECC (n = 10). Maximal voluntary isometric contraction of the KF and knee extensor (KE) muscles (MVICKF and MVICKE) was measured, and the hamstring/quadriceps strength (H/Q) ratio was calculated. Furthermore, changes in NHE maximum reaction force (NHE-MRFKF), NHE break-point angle (NHE-BPA), and muscle activity of the semitendinosus (STEMG) and biceps femoris (BFEMG) during the NHE after the interventions were compared. Although no group × time effects were observed (p = 0.09–0.70), but time effects were found for all variables. Pairwise comparisons revealed that MVICKF (+16.9%; p = 0.02), H/Q ratio (+11.8%; p = 0.01), NHE-MRFKF (+19.8%; p = 0.005), and NHE-BPA (+30.8%; p = 0.001) increased after ECC, whereas NHE-MRFKF (+9.7%; p = 0.003), NHE-BPA (+35.5%; p = 0.0002), and STEMG (+33.7%; p = 0.02) increased after NHT. A group × time effect was observed (p = 0.003) in BFEMG, revealing an increase only after ECC (+41.1%; p < 0.0001). Similar neuromuscular adaptations were found after both training modalities. Therefore, ECC provides similar adaptations as NHT and may serve as an alternative form of KF training for those unable to perform NHE.
Self-Massage Techniques for the Management of Pain and Mobility With Application to Resistance Training: A Brief Review
Authors: MacLennan Minja , Ramirez-Campillo Rodrigo , Byrne Paul J. 
Published: October 2023

AbstractMacLennan, M, Ramirez-Campillo, R, and Byrne, PJ. Self-massage techniques for the management of pain and mobility with application to resistance training: a brief review.J Strength Cond Res37(11): 2314–2323, 2023—Fascial restrictions that occur in response to myofascial trigger points (MTrP), exercise-induced muscle damage (EIMD), and delayed onset of muscle soreness (DOMS) cause soft tissue to lose extensibility, which contributes to abnormal muscle mechanics, reduced muscle length, and decrements in joint range of motion (ROM) and actively contributes to musculoskeletal pain. Resistance training and in particular, weightlifting movements have unique mobility requirements imperative for movement efficacy and safety with ROM restrictions resulting in ineffective volume and intensity tolerance and dampened force output and power, which may lead to a failed lift or injury. Self-massage (SM) provides an expedient method to promote movement efficiency and reduce injury risk by improving ROM, muscular function, and reducing pain and allows athletes to continue to train at their desired frequency with minimal disruption from MTrPs-associated adverse effects. Thus, the aim of this review was to determine the efficacy of various self-massage tools in managing pain and mobility and to explore the potential benefits of SM on resistance training performance. Many SM devices are available for athletes to manage ROM restrictions and pain, including differing densities of foam rollers, roller massagers, tennis balls, and vibrating devices. To attenuate adverse training effects, a 10-to-20-minute bout consisting of 2-minute bouts of SM on the affected area may be beneficial. When selecting a SM device, athletes should note that foam rollers appear to be more effective than roller massagers, with vibrating foam rollers eliciting an increased reduction to pain perception, and tennis balls and soft massage balls were shown to be efficacious in targeting smaller affected areas.
Laboratory Evaluation of Marginal and Industrial Waste Material in Geocell-Reinforced Pavements under Cyclic Loading
Authors: Minchala Divakar , Gottumukkala Bharath Varma , Pulikanti Subramanya Prasad , Kuna Kranthi K. 
Published: October 2023

Abstract
The availability of quality materials for the construction of pavements has been a problem in some regions. This scarcity enforced geosynthetic materials as one of the quests for su1stainability in the pavement industry. This study attempted to stabilize marginal (tunnel muck, reclaimed asphalt pavement material) and industrial waste (zinc slag) materials by employing high density polyethylene geocell to appraise the effectiveness of geosynthetic reinforcement in enhancing the characteristics of pavement materials and mitigating their rutting. The cyclic plate load tests are performed on marginal and industrial waste material with geocell-reinforced and unreinforced base layers over black cotton soil as the subgrade. The tests were conducted following the trapezoidal loading pattern with a 0.77-Hz frequency. The geocell-reinforced pavement performance was evaluated for resilient deformation, accumulated permanent deformation, rut depth reduction, traffic benefit ratio, and base layer thickness reduction. The mechanistic empirical pavement design guide (MEPDG) permanent deformation performance (PDP) model framework was used to predict the accumulated permanent deformation in unbound granular layers and to differentiate the rutting performance in geocell-reinforced and unreinforced sections. This study determined the material constants of the MEPDG PDP model for marginal and industrial waste materials used in the pavement section for quantifying the reduction in base layer thickness.
Optimization of PDMS Surface Treatment Using Atmospheric Pressure Plasma for Microfluidic Applications
Authors: Silva Lhwan Philippe , de Lara Daniel Silva , Swart Jacobus , Savu Raluca 
Published: October 2023

Abstract
Polydimethylsiloxane (PDMS) is widely used for microfluidic and biomedical applications because of its chemical inertness and affordability. However, its low surface energy limits its adhesion properties, thus necessitating mandatory surface activation, via plasma treatments or chemical processing, especially for improving its hydrophilicity. In this study, we employed an atmospheric pressure plasma jet (2 W) in order to enhance the PDMS surface adhesion for application in microfluidic devices. Treatment variables, including exposure and recovery time and adhesion quality, were investigated. It was possible to achieve a minimum exposure time of 15 s/cm2 for thin PDMS (sheet, 250 μm) and 30 s/cm2 for thick (resin, 3 mm) PDMS. A robust and efficient methodology for scaling the jet system treatment of larger areas was developed. Additionally, we examined the effect of ambient humidity on the plasma treatment. Results showed that water adsorption on PDMS-treated surfaces indicated a difference between the well-established contact angle method for determining surface hydrophilicity (and thus, its adhesion) and the real adhesion properties of the treated surfaces.
Systematic P2Y receptor survey identifies P2Y11 as modulator of immune responses and virus replication in macrophages
Authors: Andersen Line Lykke , Huang Yiqi , Urban Christian , Oubraham Lila , Winheim Elena , Stafford Che , Nagl Dennis , O'Duill Fionan , Ebert Thomas , Engleitner Thomas , Paludan Søren Riis , Krug Anne , Rad Roland , Hornung Veit , Pichlmair Andreas 
Published: October 2023

AbstractThe immune system is in place to assist in ensuring tissue homeostasis, which can be easily perturbed by invading pathogens or nonpathogenic stressors causing tissue damage. Extracellular nucleotides are well known to contribute to innate immune signaling specificity and strength, but how their signaling is relayed downstream of cell surface receptors and how this translates into antiviral immunity is only partially understood. Here, we systematically investigated the responses of human macrophages to extracellular nucleotides, focusing on the nucleotide‐sensing GPRC receptors of the P2Y family. Time‐resolved transcriptomic analysis showed that adenine‐ and uridine‐based nucleotides induce a specific, immediate, and transient cytokine response through the MAPK signaling pathway that regulates transcriptional activation by AP‐1. Using receptor trans‐complementation, we identified a subset of P2Ys (P2Y1, P2Y2, P2Y6, and P2Y11) that govern inflammatory responses via cytokine induction, while others (P2Y4, P2Y11, P2Y12, P2Y13, and P2Y14) directly induce antiviral responses. Notably, P2Y11 combined both activities, and depletion or inhibition of this receptor in macrophages impaired both inflammatory and antiviral responses. Collectively, these results highlight the underappreciated functions of P2Y receptors in innate immune processes.
Assessment Of Industrial Waste and Additives Materials Use in The Sustainable Design of Concrete
Authors: Udayasree Bakigari , Kumar G. Shravan 
Published: October 2023

The sustainable design of concrete is of paramount importance in the construction industry as it strives to minimize environmental impact while maintaining performance and durability. A key aspect of this endeavor is the assessment and integration of industrial waste materials and additives into concrete formulations. Concrete is the most frequently used construction material in the world. Each year, over ten billion tonnes of concrete are produced, resulting in the depletion of natural resources and a colossal carbon footprint. One of the primary objectives of contemporary concrete technology is to reduce the use of Portland cement and natural fine aggregates by partially substituting them with various waste materials and industrial byproducts. This paper summarises the findings of a study in which steel slag aggregate, silica fume and glass refuse were successfully used to partially replace river sand and Portland cement.
Pedagogical Views and Educational Activities of Ismail Gasprinsky
Authors: Хайруддинов Мухиддин 
Published: October 2023

The article deals with the pedagogical and educational activities of the outstanding son of the Crimean Tatar people Ismail Gasprinsky (1851–1914). Accumulating the achievements of the advanced pedagogical practice of Europe, I. Gasprinsky acted as a spokesman for the need for socio-economic changes in the countries of the East. I. Gasprinsky spoke up for the synthesis of Muslim doctrine and the achievements of modern science, he created and led the Jadid pedagogical movement aimed at the transition from confessional and Russian civic education to the creation of a national secular education.
All his life I. Gasprinsky was defending the interests of the Crimean Tatars, Mus- lims and societies living in conditions of colonial slavery. Gasprinsky was one of the most outstanding thinkers of the Turkic world. UNESCO declared 2014 the year of Ismail Gasprinsky for his contribution to education and philosophy.
The study showed that the modern interest in I. Gasprinsky is caused by the increasingly unfolding globalization and the formation of an ecological-humanistic civilization, as a new form of preserving cultural diversity in its entirety.
Size matters: identity of culturally important herrings in northeastern Brazil
Authors: Ferreira-Araújo Thais , Lopes Priscila Fabiana Macedo , Lima Sergio Maia Queiroz 
Published: October 2023

Fishery statistics are mainly made by recording the popular fish names, which is later translated into scientific identification. However, these names often either refer to a species group and/or vary along their distribution, increasing identification uncertainty. Species that have cultural value for traditional communities are known as culturally important species (CIS). Herein, we assessed Fishers’ Ecological Knowledge to investigate small-silvery herrings (ginga) used as part of a traditional dish \ginga com tapioca", that is recognized as a cultural heritage in the Brazilian northeastern. Through 103 interviews conducted in six communities in three states, we determined that ginga, although a name known elsewhere, is only traded as such in the metropolitan area of Natal. In this region, ginga is caught with drift net and deemed profitable by fishers. We identified both over- and under-differentiation, with ginga recognized by fishers as five, and sold as three main species, namely Opisthonema oglinum, Harengula sp., and Lile piquitinga. The larger specimens of two of those species (O. oglinum and Harengula sp.) were also traded as sardines. We found that most individuals sold as ginga were juveniles, which might impact the recruitment of some fish species. Due to its unique cultural relevance to the local community of Natal, ginga could be considered a CIS, which could aid future management or conservation measures.
IMPACTO DE UMA AÇÃO DE EXTENSÃO SOBRE MEDIDAS DE BIOSSEGURANÇA EM UMA ESCOLA DE ENSINO FUNDAMENTAL
Authors: Kley Louise Gabriele , Alves Thainá Mayer , De Paula Daniel , Sampaio Tuane Bazanella 
Published: October 2023

As práticas de biossegurança dizem respeito à proteção da vida, possuindo como objetivo a criação de barreiras entre o indivíduo e os agentes patológicos presentes no meio. Contudo, essa proteção só é possível quando as medidas de biossegurança são adotadas de forma correta. Neste contexto, este trabalho apresenta o impacto de uma ação de extensão com enfoque em informar e conscientizar sobre a higienização adequada das mãos, o uso do álcool etílico 70% (p/p) e o uso correto de máscaras para alunos do ensino fundamental. A ação ocorreu em setembro de 2021, durante a pandemia causada pelo vírus SARS-CoV-2, com alunos do 6° e 7° ano do ensino fundamental de uma escola da cidade de Guarapuava-PR. O impacto da ação de educação em saúde foi mensurado por meio da aplicação de questionários pré- e pós-ação. Com base nos resultados obtidos, foi observado que os alunos já sabiam da necessidade do uso de sabão /sabonete para a higienização das mãos, realizavam a lavagem das máscaras de tecido diariamente e as utilizam durante o intervalo das aulas. De destaque, a realização da ação implicou na elucidação do tempo correto para lavagem das mãos, da porcentagem para o álcool etílico ser efetivo como agente antisséptico, da identificação dos diferentes tipos de máscaras disponíveis e do tempo máximo de utilização destas. Portanto, conclui-se que esta ação de educação em saúde foi efetiva em agregar conhecimento e conscientização aos alunos sobre as medidas de biossegurança, essenciais no combate de doenças infecciosas.
Survival of unconstrained ceramic wrist joint implants
Authors: Aleksandrov T. I. , Simonova E. N. , Lukinov V. L. 
Published: October 2023

Introduction Survival of implants is an important indicator of improvement in the patient's quality of life. In foreign literature, the issue of implant survival finds special attention.The aim of the work was to evaluate the efficacy and survival of an unconstrained ceramic wrist joint endoprosthesis.Materials and methods We analysed 83 cases of total wrist arthroplasty with an unconstrained ceramic implant at long-term follow-up. At the Novosibirsk RSITO, total wrist arthroplasty was performed in 81 patients with severe changes in the wrist joint from 2011 to 2021. Two patients underwent arthroplasty on two joints. A retrospective uncontrolled cohort study was conducted which divided the hospitalized patients into three groups according to the etiological cause of the disease. Radiological methods were used to control the state of the implant (radiography in two projections and CT-scans of the wrist joint). For binary indicators, the number, rates and 95 % confidence interval of frequencies were calculated according to the Wilson formula in the groups. Comparison was carried out by Fisher's exact two-sided test. The p-error was corrected using the Benjamini – Hochberg method. Kaplan – Meier curves were constructed for survival analysis. The groups were compared using a generalized chi-square test.Results Each case of repeated surgical intervention was evaluated from the standpoint of selected groups. Depending on the time elapsed from surgery to revision, we calculated the time frame for overall and group survival of the components of the wrist joint endoprosthesis. The causes and scope of surgical revision are presented.Discussion There are no data on the survival of unconstrained ceramic wrist joint implants in the foreign literature. Graphic images according to a proposal for the division of the orthopaedic postoperative period are presented. Conclusions 1. Intermediate conclusions in regard to total arthroplasty with an unconstrained ceramic endoprosthesis of the wrist joint inspire optimism in obtaining a stable positive effect of motion range lost due to the degenerative process in the wrist joint. 2. An 11-year follow-up period demonstrates that the survival rate of an unconstrained ceramic wrist endoprosthesis is 88 %.
Biomechanics of the proximal interphalangeal joint after total joint replacement
Authors: Kotelnikov G. P. , Kolsanov A. V. , Nikolaenko A. N. , Zgirskii D. O. , Doroganov S. O. 
Published: October 2023

Introduction Small joints arthroplasty of the hand including the proximal interphalangeal joint (PIPJ) is associated with the need to create anatomically adapted structures using optimal materials. Introduction of a new medical device requires comprehensive preclinical testing.The objective was to determine a range of loads allowed for the proximal interphalangeal joint after arthroplasty through analyzing the biomechanics to prevent critical conditions and complications.Methods A full-ceramic non-constrained anatomically adapted proximal interphalangeal joint implant was developed between 2016 and 2021 using an integrated approach with preclinical trials and a clinical study of 42 patients (25 males, 17 females) with PIPJ arthritis. A digital endoprosthesis was created with 3D-modelling. Critical conditions for the digital model imitating typical joint movements were explored with the use of finite element method and the findings to be employed in clinical practice.Results A stable biomechanical construct was intact with loads of 5 kilograms and a motion ranging from 0 to 60 degrees, with loads of 20 kilograms and a motion ranging between 0 and 30 degrees. Cortical bone could sustain loads up to 20 kilograms with a motion ranging between 0 and 60 degrees. Discussion Load capacity of the implant was explored considering the strength of bone tissue and zirconium ceramics as a material. The study set a vector for the development of the optimal mode of motor activity early after surgery and indicated the optimal range of motion to be applied after PIPJ arthroplasty.Conclusion The load up to 5 kg was optimal for the patient to be applied early after surgery with the range of flexion measuring less that 90°. The patient could use a load of 5 to 20 kg with flexion in the proximal interphalangeal joint measuring less than 30°. Endoprosthetic components were likely to get dislocated with a load of 20 kg and flexion angle of greater than 30°. Periprosthetic fracture could occur with flexion angle of greater than 60°.
The effect of previous surgical treatment on the outcome of total hip replacement in young patients with dysplastic coxarthrosis
Authors: Teplenkiy M. P. , Kaminsky A. V. , Fozilov D. T. 
Published: October 2023

Introduction Hip dysplasia of various genesis is recognized as a common cause of coxarthrosis. Total hip replacement (THR) is the operation of choice for the patients with the final stage of the pathological process. There are different opinions on the impact of previous surgical treatment of hip dysplasia on THR.The aim of the study was to explore the effects of previous surgical treatment on the outcomes of THR in young patients with dysplastic and secondary coxarthrosis.Material and methods Surgical outcomes of 78 patients (58 females and 20 males; 91 joints) with dysplastic and secondary coxarthrosis (age 14-30 years, average age 24.3 ± 4.3 years) treated witrh THR were retrospectively reviewed. Patients we assigned to two groups. Group I (control) included 27 patients (33 joints) with dysplastic coxarthrosis primarily treated with THR. Group II (treatment group) included 51 patients (58 joints) who had previously undergone THR.Results Patients of group II demonstrated longer duration of surgery by 47.89 %, greater blood loss by 16.92 % and the higher complication rate by 42.1 %.Discussion The treatment group showed a significantly increased frequency of late complications in the form of implant instability. Patients of group II dermonstrated better functional results estimated with HHS as compared to the outcomes of patients of group I.Conclusion Hip reconstructions performed earlier were associated with technical difficulties, aggressive THR procedure, a greater risk of late complications, but showed no significant effect on the outcomes.
Comparison of the strength characteristics of a carbon friction pair of a hip joint endoprosthesis, including components from monolithic or non-monolithic pyrolytic carbon
Authors: Mitroshin A. N. , Ksenofontov M. A. , Kosmynin D. A. 
Published: October 2023

Introduction The problem a large number of revision operations due to aseptic loosening after primary hip arthroplasty necessitates the search for a new material for a friction pair. The pyrocarbon, which has high tribological characteristics, can be used both in a monolithic and in a prefabricated design; however, the manufacture of a monolithic pyrocarbon block complicates production.Aim Compare the strength characteristics of the stem head and liner designs with monolithic and non-monolithic pyrocarbon.Materials and methods To assess the reliability of the designs, a digital mathematical model of the head and liner implants with a monolithic and non-monolithic pyrocarbon component was built. After the manufacture of prototypes friction pairs, an assessment of the static load on bench tests was carried out.Results While analyzing the mathematical model, the construct of non‑monolithic pyrocarbon broke in one of the experiments, while the strength of the construct of monolithic pyrocarbon was 4.5 times higher than the stresses arising under load. While studying the maximum static load, the friction pair from monolithic pyrocarbon exceeded the maximum possible load in the human hip joint by 5 times.Discussion The studies allow us to be confident about the reliability of the design in in vitro studies, which will create conditions for reducing the number of revision surgeries after hip arthroplasty.Conclusion Based on the data obtained, the design of the head and liner of the hip joint endoprosthesis with a friction pair made of carbon material will provide high reliability under conditions of functioning in the hip joint at maximum loads. It serves as a prerequisite for conducting a clinical study of the proposed friction pair.