bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gambaran Hasil Pemeriksaan Ekokardiografi Pasien Gagal Jantung di RSUP H. Adam Malik pada Tahun 2021
Authors: Surbakti Trifena Aurelya Rimna , Lubis Anggia Chairuddin 
Published: December 2023

Pendahuluan. Angka kejadian penyakit gagal jantung masih terus meningkat di tingkat global. Dalam mendiagnosis dan mengevaluasi penyakit gagal jantung, terdapat beberapa modalitas yang dapat diandalkan, salah satunya adalah ekokardiografi. Metode pemeriksaan ekokardiografi berguna dalam banyak aspek termasuk penilaian fungsi dan diameter jantung, yang secara klinis menjadi landasan dalam pilihan pengobatan dan prognosis penderita gagal jantung. Tujuan. Tujuan penelitian ini adalah untuk mengetahui gambaran hasil pemeriksaan ekokardiografi pasien gagal jantung di RSUP H. Adam Malik Medan pada tahun 2021. Metode. Penelitian ini memiliki desain deskriptif retrospektif dengan pendekatan potong lintang (cross sectional). Hasil. Mayoritas penderita berasal dari kalangan usia produktif. 73,62% pasien berjenis kelamin laki-laki. Etiologi terbanyak pada penelitian ini adalah penyakit iskemik. Ditemukan 49,08% sampel mengalami hipertrofi eksentrik, 46,63% mengalami hipertrofi konsentrik, 1,84% mengalami remodelling konsentrik, dan 2,45% memiliki geometri LV yang normal. Rata rata LVEF adalah 44,70% dengan HFpEF yang paling mendominasi. 77,30% memiliki TAPSE normal dan dari 121 data yang tersedia, 46,63% mengalami disfungsi diastolik grade I, 14,72% mengalami disfungsi diastolik grade III, dan sisanya, 12,88% mengalami disfungsi diastolik grade II. Kesimpulan. Kebanyakan pasien gagal jantung di RSUP H. Adam Malik Medan pada tahun 2021 berasal dari kalangan usia produktif. Etiologi tersering adalah penyakit iskemik. Dimensi dan volume LV mayoritas pasien hipertrofi eksentrik. HFpEF mendominasi dan TAPSE kebanyakan normal. Dari 121 data mengenai disfungsi diastolik LV, disfungsi grade I merupakan yang terbanyak.

Kata Kunci: gagal jantung, ekokardiografi, LVEF, TAPSE, gambaran
Laporan Kasus Tinea Cruris et Corporis Menahun pada Pasien Usia 60 Tahun di RS Martha Friska Multatuli Medan
Authors: Thanita Viktoria 
Published: December 2023

ABSTRAK
Latar Belakang: Dermatofitosis adalah penyakit jamur superfisial, dengan penyebab Microsporusm, Trichopythonm, dan Epidermophyton. Tinea cruris adalah dermatofitosis superfisial pada lipat paha, pubis, daerah perineum, dan sekitar anus. Tinea korporis merupakan dermatofitosis superfisial pada kulit tidak berambut (glabrous skin). Pada tinea korporis yang menahun dapat terjadi bersama dengan tinea cruris yang disebut tinea corporis et cruris atau sebaliknya tinea cruris et corporis. Tujuan: Melaporkan satu kasus Tinea kruris et korporis pada pasien lansia di RS. Martha Friska Multatuli Medan. Ilustrasi Kasus: Seorang laki-laki lansia, usia 60 tahun datang dengan keluhan gatal dan bercak kemerahan. Didapati gambaran klinis berupa bercak kemerahan pada selangkangan kiri dan kanan, paha kiri dan kanan, daerah kelamin, daerah bokong kiri dan kanan, pinggul kanan dan perut. Pembahasan: Diagnosis ditegakkan berdasarkan anamnese dan pemeriksaan fisik dermatologi. Pengobatan diberikan Ketokonazol tablet, Krim Mikonazol 2%, dan cetirizin tablet. Edukasi yang diberikan menjaga higienitas. Kesimpulan: Terdapat perbaikan klinis pasien dengan pengobatan selama 14 hari.
Kata Kunci: dermatofitosis, jamur superfisial, tinea corporis, tinea cruris, tinea cruris et corporis

ABSTRACT
Background: Dermatofitosis is superficial fungal infection, caused by Microsporusm, Trichopythonm and Epidermophyton. Tinea cruris is superficial dermatofitosis in groin, pubic area, perineum, and perianal. Tinea corporis is superficial dermatofitosis on glaborus skin. Tinea corporis cronic can be coincidence with tinea cruris and called tinea corporis et cruris or tinea cruris et corporis. Objectives: Reported one case of tinea cruris et corporis of old man in Martha Friska Multatuli Medan. Case Illustration: A patience, 60 years old came with ithcy and reddish spot. The clinical featured reddish spot on right groin, left and right femur, pubic area, left and right gluteus, perianal, and stomach and right cruris. Discussion: Diagnose based on anamnese and dermatology phycal examination. Therapetic are Ketoconazol tablet 200mg 2x1, cream mikonazol 2% 2x1, and cetirizin tablet 1x1. Education keep hyginity. Conclusion: In this patience, there is clinical improvement in 14 days therapeutic.
Keywords: dermatofitosis, superficial fungal, tinea corporis, tinea cruris, tinea cruris et corporis
ОПЕРАТИВНО-ВІЙСЬКОВІ ВІДДІЛИ ДЕРЖАВНОЇ ПРИКОРДОННОЇ СЛУЖБИ УКРАЇНИ В ОХОРОНІ ЛІНІЇ РОЗМЕЖУВАННЯ НА ТЕРИТОРІЇ ДОНЕЦЬКОЇ ТА ЛУГАНСЬКОЇ ОБЛАСТЕЙ (2014–2015 рр.)
Authors: АНАНЬЇН Олег 
Published: December 2023

Проаналізовано досвід службово-бойової діяльності оперативно-вій- ськових відділів Державної прикордонної служби України «Краматорськ» та «Велика Новосілка», які здійснювали охорону лінії розмежування у ме- жах Донецької та Луганської областей у 2014–2015 рр. В якості хроно- логічних меж дослідження визначено вересень 2014 – серпень 2015 рр., що було періодом розгортання, становлення та реорганізації оператив- но-військових відділів як самостійних прикордонних підрозділів та вико- нання ними службово-бойових завдань на територіях, прилеглих до лінії розмежування у районі проведення антитерористичної операції. Наведе- но основні чинники оперативної обстановки, що впливали на організацію діяльності прикордонних підрозділів під час охорони лінії розмежування.\ Службово-бойова діяльність оперативно-військових відділів проде- монструвала, що створення ефективної системи охорони лінії розмежу- вання ускладнювалося без застосування спеціально сформованих для цьо- го підрозділів, оснащених відповідною технікою та засобами. З метою врегулювання законодавчих питань щодо охорони лінії розмежування прикордонними підрозділами Адміністрацією Державної прикордонної служби України було ініційовано внесення відповідних змін у норматив- но-правові документи. Запроваджені законодавчі зміни дозволили уповно- важити прикордонників здійснювати контроль за в’їздом/виїздом грома- дян та перевезенням вантажів через лінію розмежування. Охорону лінії розмежування оперативно-військові відділи здійснювали шляхом прове- дення оперативно-службових та службово-бойових дій як самостійно, так і у взаємодії із ЗС України, СБУ та МВС.
Варто зазначити, що невеликий період службово-бойової діяльності оперативно-військових відділів у якості самостійних структурних під- розділів продемонстрували їхню ефективність у виконанні правоохорон- них та військових завдань.
ПРАВОВІ ЗАСАДИ СИСТЕМИ БОРОТЬБИ З МІЖНАРОДНИМ ТЕРОРИЗМОМ У КРАЇНАХ-ЧЛЕНАХ НАТО
Authors: БІЛЮГА Андрій 
Published: December 2023

Боротьба з тероризмом вимагає застосування національних і міжнародних механізмів, які сьогодні активно діють у країнах Північноатлантичного Альянсу. Значущість дослідження ролі НАТО як міжнародної організації у сучасній системі боротьби із міжнародним тероризмом важ- лива, оскільки йдеться про боротьбу з найнебезпечнішими загрозами миру та безпеці людства.
Маючи значний довід у різних сферах забезпечення безпеки, НАТО робить вагомий внесок у бо- ротьбу з міжнародним тероризмом. Окрім спільних зусиль, країни-члени Альянсу розробляють власну внутрішньодержавну політику боротьби з тероризмом. Сутність цієї політики спрямова- на на задоволення, в першу чергу національних, і лише в другу — загальносоюзних чи спільних цілей Aльянсу. Це означає, що політичне керівництво кожної країни виробляє таку систему заходів бо- ротьби, що враховують насамперед національні інтереси та власні спроможності, але при цьому країни завжди застосовують антитерористичний потенціал НАТО.
Спрямованість внутрішньої політики держав-членів НАТО полягає у тому, що вони можуть планувати заходи боротьби з міжнародним тероризмом, виходячи далеко за межі власних ресур- сних можливостей, оскільки завжди можуть залучити спільні зусилля інших країн-членів НАТО, або брати участь у вже діючих програмах та операціях у боротьбі з міжнародним тероризмом. Актуальність дослідження полягає у вивченні сучасного стану та тенденцій розвитку бо- ротьби провідних країн Альянсу та НАТО як організації у загальній системі боротьби з міжнародним тероризмом.
Pengaruh Beban Kerja dan Lingkungan Kerja Terhadap Kinerja Karyawan (Studi Kasus Pada Bagian Keperawatan Rumah Sakit Nahdlatul Ulama Jombang)
Authors: Sari Zhelika , Mahfudiyanto  , Laili Choirun Nisful 
Published: December 2023

Penelitian ini bertujuan untuk mengetehui “pengaruh beban kerja dan lingkungan kerja terhadap kinerja karyawan Rumah Sakit Nahdlatul Ulama Jombang”. Penelitian ini menggunakan metode kuantitatif. Untuk kajian ini populasinya yaitu seluruh perawat RS Nahdlatul Ulama Jombang. Digunakannya sampel jenuh selaku teknik pengambilan sampelnya, dimana sampelnya berjumlah 60 karyawan. Teknik pengumpul data mempergunakan kuesioner yang telah dilakukan uji reliabilitas dan vaaliditasnya. Uji asumsi klasik mencakup uji normalitas, multikoloniearitas dan heteroskedastisitas, menggunakan analisis regresi linier berganda serta uji hipotesis (uji t dan F) serta uji koefisien determinasi. Hasil penelitiannya untuk uji t (parsial) memperlihatkan bahwa variabel beban kerja (X1) memengaruhi positif kinerja karyawannya (Y) serta variabel lingkungan kerja (X2) memengaruhi positif kinerja karyawannya (Y). Hasil penelitiannya untuk uji F (simultan) dihasilkan bahwa beban kerja (X1) dan lingkungan kerja (X2) memengaruhi signifikan kinerja karyawan (Y) secara simultan
Pengaruh Kinerja Keuangan Terhadap Social Responsibility Perusahaan pada PT. Unilever Indonesia Tbk
Authors: Kurniawan Widiar Onny , Estiasih Soffia Pudji , Maharani Gintan Regita 
Published: December 2023

This study has the aims of detecting the impact of ROA and ROE on CSR, the population of the financial statemenst of PT. Unilever Indonesia Tbk, sample of financial statements starting from 2018-2020 obtained 36 samples, the sampling mechanism is purposive sampling. As well as information collection techniques using documentation. Material testing using classical assumption test, multiple linear regression data analysis, hypothesis t test and F test. Based on simultaneous testing, the ROA impact on CSR is 0,000<0,05, ROE has an impact on CSR 0,033<0,05. The implementation of better corporate social responbility can practice good things for the sustainability of the company in the long term. CSR disclosure can also show that a company is carring out its obligations properly according to existing regulations and the surrounding population and environment of the company. With the activities carried out by CSR, the company can give people confidence in the company’s products after which the good name of the company becomes excellent in the eyes of the population, and can grow financial capacity which can be shown from the ROA and ROE ratio.
Pengaruh Liabilitas dan Good Corporate Governance terhadap Tax Avoidance Perusahaan Food and Beverage pada Bursa Efek Indonesia Tahun 2017 – 2021
Authors: Parso Parso 
Published: December 2023

This study aims to determine the effect of liabilities and good corporate governance (independent commissioners, audit committees, and institutional ownership) on tax avoidance in food and beverage companies listed on the IDX. The research conducted is quantitative research used to test hypotheses using statistical analysis tools regarding tax avoidance. Using secondary data by analyzing financial reports on food and beverage companies listed on the Indonesia Stock Exchange (IDX) for the period 2017 - 2021. Based on the data analysis conducted, it is found that liability has a positive and significant effect on tax avoidance, Independent Commissioner does not affect tax avoidance, Institutional Ownership has a negative and significant effect on tax avoidance, and the Audit Committee has no effect on tax avoidance in food and beverage companies listed on the Indonesia Stock Exchange for the period 2017 - 2021.
Abstrak
Penelitian ini bertujuan untuk mengetahui pengaruh liabilitas dan good corporate governance yang terdiri dari variabel, komisaris independent, komite audit dan kepemilikan institusional terhadap tax avoidance pada perusahaan food and beverage yang terdaftar di BEI. Penelitian yang dilakukan adalah penelitian kuantitatif yang dipakai guna menguji hipotesis dengan menggunakan alat analisis statistik mengenai penghindaran pajak (tax avoidance). menggunakan data sekunder dengan cara menganalisis laporan keuangan pada perusahaan food and beverage yang terdaftar di Bursa Efek Indonesia (BEI) periode tahun 2017 – 2021. Berdasarkan analisis data yang dilakukan didapatkan hasil bahwa Liabilitas berpengaruh positif dan signifikan terhadap tax avoidance, Komisaris Independen tidak berpengaruh terhadap tax avoidance, Kepemilikan Institusional berpengaruh negatif dan signifikan terhadap tax avoidance, dan Komite Audit tidak berpengaruh terhadap tax avoidance pada perusahaan food and beverage yang terdaftar di Bursa Efek Indonesia periode 2017 – 2021.
Kata Kunci: Liabilitas, Komisaris, Kepemilikan, Komite Audit, Penghindaran Pajak
ÉTICA NO METAVERSO
Authors: De Assis Espinosa José Mauricio 
Published: December 2023

Uma reflexão diante das novas perspectivas tecnológicas e suas implicações na sociedade atual, considerando as tendências sociais ante as redes, mundos virtuais, metaverso e inteligência artificial. Ponderando as questões éticas nestes ambientes e suas projeções sobre a vida real, de forma a se entrar em um dilema filosófico já observado desde a caverna de Platão, mas reeditado e atualizado hoje no conceito do metaverso e suas ações efetivas na vida das pessoas. Avaliando a modernidade líquida, que ironicamente se solidifica como uma realidade ainda mais forte a cada dia, onde as pessoas vivem mais as vidas virtuais do que suas existências reais, criando uma atualização do paradigma do existir, do ser em seu conceito e a sua representação virtual, que de certa forma também é real, pois age de forma a executar ações palpáveis e com implicação real na vida de seus representantes humanos e vice versa.
Maternal consumption of a high-fat diet modulates the inflammatory response in their offspring, mediated by the M1 muscarinic receptor
Authors: Costa Suleyma Oliveira , Chaves Wenicios Ferreira , Lopes Priscilla Karla Fernandes , Silva Iracema M. , Burguer Beatriz , Ignácio-Souza Leticia M. , Torsoni Adriana Souza , Milanski Marciane , Rodrigues Hosana Gomes , Desai Mina , Ross Michael Glenn , Torsoni Marcio Alberto 
Published: December 2023

IntroductionHigh-fat diet (HFD) consumption is associated with various metabolic disorders and diseases. Both pre-pregnancy and maternal obesity can have long-term consequences on offspring health. Furthermore, consuming an HFD in adulthood significantly increases the risk of obesity and metabolic disorders. However, an intriguing phenomenon known as the obesity paradox suggests that obesity may confer a protective effect on mortality outcomes in sepsis. In sepsis, activation of the cholinergic anti-inflammatory pathway (CAP) can help mitigate systemic inflammation. We employed a metabolic programming model to explore the relationship between maternal HFD consumption and offspring response to sepsis.MethodsWe fed female mice either a standard diet (SC) or an HFD during the pre-pregnancy, pregnancy, and lactation periods. Subsequently, we evaluated 28-day-old male offspring. ResultsNotably, we discovered that offspring from HFD-fed dams (HFD-O) exhibited a higher survival rate compared with offspring from SC-fed dams (SC-O). Importantly, inhibition of the m1 muscarinic acetylcholine receptor (m1mAChR), involved in the CAP, in the hypothalamus abolished this protection. The expression of m1mAChR in the hypothalamus was higher in HFD-O at different ages, peaking on day 28. Treatment with an m1mAChR agonist could modulate the inflammatory response in peripheral tissues. Specifically, CAP activation was greater in the liver of HFD-O following agonist treatment. Interestingly, lipopolysaccharide (LPS) challenge failed to induce a more inflammatory state in HFD-O, in contrast to SC-O, and agonist treatment had no additional effect. Analysis of spleen immune cells revealed a distinct phenotype in HFD-O, characterized by elevated levels of CD4+ lymphocytes rather than CD8+ lymphocytes. Moreover, basal Il17 messenger RNA (mRNA) levels were lower while Il22 mRNA levels were higher in HFD-O, and we observed the same pattern after LPS challenge. DiscussionFurther examination of myeloid cells isolated from bone marrow and allowed to differentiate showed that HFD-O macrophages displayed an anti-inflammatory phenotype. Additionally, treatment with the m1mAChR agonist contributed to reducing inflammatory marker levels in both groups. In summary, our findings demonstrate that HFD-O are protected against LPS-induced sepsis, and this protection is mediated by the central m1mAChR. Moreover, the inflammatory response in the liver, spleen, and bone marrow-differentiated macrophages is diminished. However, more extensive analysis is necessary to elucidate the specific mechanisms by which m1mAChR modulates the immune response during sepsis.
Machine learning-based clinical decision support for infection risk prediction
Authors: Feng Ting , Noren David P. , Kulkarni Chaitanya , Mariani Sara , Zhao Claire , Ghosh Erina , Swearingen Dennis , Frassica Joseph , McFarlane Daniel , Conroy Bryan 
Published: December 2023

BackgroundHealthcare-associated infection (HAI) remains a significant risk for hospitalized patients and a challenging burden for the healthcare system. This study presents a clinical decision support tool that can be used in clinical workflows to proactively engage secondary assessments of pre-symptomatic and at-risk infection patients, thereby enabling earlier diagnosis and treatment.MethodsThis study applies machine learning, specifically ensemble-based boosted decision trees, on large retrospective hospital datasets to develop an infection risk score that predicts infection before obvious symptoms present. We extracted a stratified machine learning dataset of 36,782 healthcare-associated infection patients. The model leveraged vital signs, laboratory measurements and demographics to predict HAI before clinical suspicion, defined as the order of a microbiology test or administration of antibiotics.ResultsOur best performing infection risk model achieves a cross-validated AUC of 0.88 at 1 h before clinical suspicion and maintains an AUC &gt;0.85 for 48 h before suspicion by aggregating information across demographics and a set of 163 vital signs and laboratory measurements. A second model trained on a reduced feature space comprising demographics and the 36 most frequently measured vital signs and laboratory measurements can still achieve an AUC of 0.86 at 1 h before clinical suspicion. These results compare favorably against using temperature alone and clinical rules such as the quick sequential organ failure assessment (qSOFA) score. Along with the performance results, we also provide an analysis of model interpretability via feature importance rankings.ConclusionThe predictive model aggregates information from multiple physiological parameters such as vital signs and laboratory measurements to provide a continuous risk score of infection that can be deployed in hospitals to provide advance warning of patient deterioration.
Predictors of futile recanalization in basilar artery occlusion patients undergoing endovascular treatment: a post hoc analysis of the ATTENTION trial
Authors: Yi Tingyu , Li Kai , Lin Xiao-hui , Lin Ding-lai , Wu Yan-Min , Pan Zhi-nan , Zheng Xiu-fen , Chen Rong-cheng , Zeng Guoyong , Chen Wen-huo 
Published: December 2023

BackgroundFew studies have focused on factors associated with futile recanalization in patients with an acute basilar artery occlusion (BAO) that was treated with modern endovascular therapy (EVT). The aim of this study was to explore the factors associated with futile recanalization in patients with an acute BAO presented within 12 h.MethodsThis is a post-hoc analysis of the ATTENTION trial (The Trial of Endovascular Treatment of Acute Basilar-Artery Occlusion, ClinicalTrials.gov, number NCT 04751708). Demographics, clinical characteristics, acute stroke workflow interval times, and imaging characteristics were compared between the futile recanalization and favorable recanalization groups. The favorable outcome was defined as a modified Rankin scale (mRS) score of 0–3 at 90 days, successful reperfusion was defined as thrombolysis in cerebral infarction (TICI) 2b and 3 on the final angiogram, and futile recanalization was defined as failure to achieve a favorable outcome despite successful reperfusion. A multivariate analysis was performed to identify the predictors of futile recanalization.ResultsIn total, 185 patients were included in the final analysis: 89 (48.1%) patients had futile recanalization and 96 (51.9%) patients had favorable recanalization. In the multivariable logistic regression analysis, older age (OR 1.04, 95% CI 1.01 to 1.08, p = 0.01) and diabetes mellitus (OR 3.35, 95% CI 1.40 to 8.01, p = 0.007) were independent predictors of futile recanalization.ConclusionFutile recanalization occurred in nearly half of patients with acute BAO following endovascular treatment. Old age and diabetes mellitus were identified as independent predictors of futile recanalization after endovascular therapy for acute BAO.
Overtaking collision avoidance for small autonomous uncrewed aircraft using geometric keep-out zones
Authors: Hawes Nathaniel C. , Wilhelm Jay P. 
Published: December 2023

Autonomous uncrewed aircraft will require collision avoidance systems (CASs) designed with autonomy in mind as they integrate into the increasingly crowded national airspace system. Current uncrewed aircraft CASs typically require a remote pilot to execute avoidance or to provide poorly defined guidance that does not benefit autonomous systems. The Path Recovery Automated Collision Avoidance System (PRACAS) re-plans flight paths to autonomously adjust for collisions using path planners and keep-out zones (KOZs), but it does not currently detect or mitigate overtaking collisions. This work investigates the effect of geometric KOZs on overtaking scenarios for autonomous uncrewed aircraft. KOZ shapes were developed by relating relative velocities and turn rates of aircraft in overtaking scenarios and were tested using PRACAS. The operational ranges for approach heading, relative velocity, and look-ahead time were then determined. The set of KOZs that were developed prevented intruder aircraft from entering the minimum separation distance of one wingspan from the mission aircraft in overtaking scenarios with look-ahead times between 5 and 12 s, relative velocities of 2–20, and approach angles between 110° and −110° measured from the heading of the main UAS. Minimum separation was maintained for low-speed encounters with relative velocities between 1.1 and 2.0 for look-ahead times between 2 and 8 s for all approach angles. With look-ahead times ranging from 5 to 8 s, overtaking collisions of all tested approach angles and relative speeds are handled with more than twice the separation required for success, showing that the KOZs developed are feasible in possible autonomous CASs.