bluuebunny/crossref_metadata_2025_split huggingface dataset:
Comprehensive analysis of performance, physiological, and perceptual responses during an entire sprint cross-country skiing competition
Authors: Talsnes Rune Kjøsen , Berdal Tore , Brattebø Jan-Magnus , Seeberg Trine , Losnegard Thomas , Kocbach Jan , Sandbakk Øyvind 
Published: October 2023

Abstract
Purpose
To investigate performance, physiological, and perceptual responses of an entire sprint cross-country skiing competition in the skating style.

Methods
Eighteen national-level male junior skiers participated in a simulated competition comprising an individual time trial (TT), followed by three heats (quarterfinals [QF], semifinals [SF], and final [F]). Participants’ heart rate (HR) was continuously monitored while perceived readiness (RED, 1–10), rating of perceived exertion (RPE, 6–20), and blood lactate [La-] were assessed at standardized time points.

Results
The total duration and distance covered were 03:30 ± 00:06 h and 25.2 ± 2.9 km, respectively. The participants spent 02:19 ± 00:27 h > 60% of their maximal HR (HRmax) and 00:16 ± 00:04 h > 85% of HRmax. Average HR decreased from TT to F (89.3 ± 2.0% vs. 86.9 ± 3.0% of HRmax, P < 0.01). [La-] levels were highest before (4.6 ± 2.0 vs. 2.9 ± 1.2, 3.2 ± 2.0 and 2.5 ± 1.3 mmol·L−1, all P < 0.01) and after (10.8 ± 1.4 vs. 9.8 ± 1.6, 9.1 ± 1.8 and 8.7 ± 1.7 mmol·L−1, all P < 0.05) F compared to TT, QF, and SF, respectively. RED was lowest before F compared to TT, QF, and SF (6.6 ± 1.4 vs. 7.9 ± 1.1, 7.6 ± 1.1, and 7.4 ± 1.4, respectively, all P < 0.05) while RPE was highest after TT compared to QF, SF, and F (17.8 ± 0.9 vs. 15.1 ± 2.0, 16.5 ± 1.2 and 16.6 ± 1.8, respectively, all P < 0.01). The six best-performing skiers demonstrated higher RED before F (7.2 ± 0.9 vs. 5.3 ± 1.2, P < 0.05) and higher [La-] after F (11.2 ± 0.2 vs. 10.2 ± 0.3, mmol·L−1, P < 0.05) than lower-performing competitors.

Conclusion
This study provides novel insights into physiological demands of an entire sprint cross-country skiing competition, which involves repeated 3-min high-intensity efforts interspersed with > 2 h (25 km) of low- to moderate-intensity exercise.
Equine tapeworm (Anoplocephala spp.) infection: evaluation of saliva- and serum-based antibody detection methods and risk factor analysis in Slovak horse populations
Authors: Burcáková Ludmila , Königová Alzbeta , Kuzmina Tetiana A. , Austin Corrine J. , Matthews Jacqueline B. , Lightbody Kirsty L. , Peczak Natalia A. , Syrota Yaroslav , Várady Marian 
Published: October 2023

AbstractA lack of accurate information on the prevalence and distribution ofAnoplocephalaspp. infections on horse farms has led to insufficient attention to tapeworm control and increasing horse anoplocephaloses in Europe. Our study aimed to examine the occurrence ofAnoplocephalaspp. infection using coprological, serum- and saliva-based antibody detection methods and to analyze the risk factors associated with tapeworm infection in domestic horses in Slovakia. Fecal, serum, and saliva samples were collected from 427 horses from 31 farms in Slovakia. Additionally, a questionnaire study was conducted to collect information on tapeworm distribution on horse farms and analyze risk factors associated with infection. Fecal samples were examined by the mini-FLOTAC and the double centrifugation/combined sedimentation-flotation techniques. Serum and saliva samples were analyzed by ELISA to determine antibody levels againstAnoplocephalaspp. The effects of variables associated with an individual horse were tested for the positive result of the saliva ELISA test onAnoplocephalaspp. Cestode eggs were detected in 1.99% of fecal samples (farm prevalence 12.90%), with no differences between the two coprological methods. Serum-based tapeworm ELISA results revealed that 39.39% of horses tested positive (farm prevalence 83.87%); while saliva-based tapeworm ELISA results revealed 56.95% positive horses (farm prevalence 96.77%). Binary logistic regression analysis revealed four meaningful predictors that significantly impacted the likelihood of detecting tapeworm infection in horses: horse age, pasture size, anthelmintic treatment scheme, and access to pasture. The influences of other variables associated with an individual horse were not significantly associated with detecting tapeworm infection.
Financial toxicity among cancer survivors: a conceptual model based on a feedback perspective
Authors: Scheidegger Alexander , Bernhardsgrütter Daniela , Kobleder Andrea , Müller Martin , Nestor Karen , Richle Ernst , Baum Eleonore 
Published: October 2023

Abstract
Purpose
Experiencing financial toxicity following a cancer diagnosis is a circular and complex process. We investigate the circular causal mechanisms that either reinforce or balance financial toxicity dynamics.

Methods
We conducted a literature review, expert interviews, a participatory modeling process, and exploratory interviews with N = 11 adults with cancer living in Switzerland. We sampled participants purposively based on health-related and sociodemographic characteristics.

Results
We describe a conceptual model based on the triangulation of cancer survivor narratives, expert perspectives, and a literature review. This model distinguishes between the reinforcing and balancing feedback loops that drive the dynamics of financial toxicity. It includes the topics “Coping with cancer and employment,” “Coping with limited economic resources,” and “Maintaining care resources while facing economic pressure.” For each topic, we identify a necessary condition for cancer survivors to avoid reinforcing financial toxicity.

Conclusions
The results allow us to reconstruct participant narratives regarding cancer-related financial toxicity. Based on comparison with scientific literature from Western Europe and North America, we hypothesize the validity of the model beyond the population covered by the sample. The results highlight the importance of screening for the risk of financial toxicity in the clinical context and individual risk and resource assessment in social counseling.

Implications for cancer survivors
These results can raise cancer survivors’ awareness of risks related to financial toxicity and strengthen their resources for coping with financial burden successfully.
Treatment of a symptomatic cervical cerebrospinal fluid fistula after full endoscopic cervical foraminotomy with CT-guided epidural fibrin patch
Authors: Motov Stefan , Stemmer B. , Krauss P. , Maurer C. , Shiban E. 
Published: October 2023

Abstract
Background
There is only limited data on the management of cerebrospinal fluid (CSF) fistulas after cervical endoscopic spine surgery. We investigated the current literature for treatment options and present a case of a patient who was treated with CT-guided epidural fibrin patch.

Methods
We present the case of a 47-year-old female patient with a suspected CSF fistula after endoscopic decompression for C7 foraminal stenosis. She was readmitted 8 days after surgery with dysesthesia in both upper extremities, orthostatic headache and neck pain, which worsened during mobilization. A CSF leak was suspected on spinal magnetic resonance imaging. A computer tomography (CT)-guided epidural blood patch was performed with short-term relief. A second CT-guided epidural fibrin patch was executed and the patient improved thereafter and was discharged at home without sensorimotor deficits or sequelae. We investigated the current literature for complications after endoscopic spine surgery and for treatment of postoperative CSF fistulas.

Results
Although endoscopic and open revision surgery with dura repair were described in previous studies, dural tears in endoscopic surgery are frequently treated conservatively. In our case, the patient was severely impaired by a persistent CSF fistula. We opted for a less invasive treatment and performed a CT-guided fibrin patch which resulted in a complete resolution of patient’s symptoms.

Discussion and conclusion
CSF fistulas after cervical endoscopic spine procedures are rare complications. Conservative treatment or revision surgery are the standard of care. CT-guided epidural fibrin patch was an efficient and less invasive option in our case.
Flow of a limited stress fluid between plates rotating about different axes
Authors: Fusi Lorenzo , Tozzi Rebecca , Farina Angiolo , Rajagopal Kumbakonam R. 
Published: October 2023

AbstractIn this paper we study the flow of a particular type of non-Newtonian fluids generated by the rotation of parallel infinite plates about distinct axes. The constitutive law of these fluids mimics the response of a class of seemingly viscoplastic or “yield stress” materials in which the norm of the stress is bounded by a critical threshold (limited stress fluids). We assume that the plates rotate with the same angular velocity and we show that, in this case, the mathematical problem can be reduced to solving a BVP where the unknowns are the coordinates of the center of rotation. We solve the problem numerically (by means of a spectral collocation method), and we investigate the dependence of the locus of the center of rotation on the material parameters. We prove that, even for small Reynolds numbers, the flow may exhibit boundary layers depending on the particular choice of the parameters.
A novel low cybersickness dynamic rotation gain enhancer based on spatial position and orientation in virtual environments
Authors: Avola Danilo , Cinque Luigi , Foresti Gian Luca , Marini Marco Raoul 
Published: October 2023

AbstractHardware and software resources nowadays make possible new Virtual Reality (VR) interaction methods. Numerous challenges have been involved over the years, and one of the most interesting is locomotion in virtual environments. In particular, Real Walking (RW) is one of the most effective Virtual Locomotion Techniques (VLT). It causes only reduced cybersickness, but it also requires proportional real walkable space to the virtual one, often requiring wide areas. In this context, optimization techniques have been proposed in the literature, e.g., reorientation or relocation. In this work, a novel method for improving reorientation in a virtual environment, exploiting a dynamic Rotation Gain Multiplication Factor (RGMF) based on the competence of the user in VR systems usage is proposed. The results highlight the effectiveness of the system and show the specific target of users that mainly appreciated it.
To move or not to move—factors influencing small-scale herder and livestock movements in the Dzungarian Gobi, Mongolia
Authors: Michler Lena M. , Kaczensky Petra , Oyunsaikhan Ganbaatar , Bartzke Gundula S. , Devineau Olivier , Treydte Anna C. 
Published: October 2023

AbstractIn Mongolia, where nomadic pastoralism is still practiced by around one-third of the population, increasing livestock numbers, socio-economic constraints and climate change raise concerns over rangeland health. Little empirical evidence explains what triggers camp moves of pastoralists in the Dzungarian Gobi in Mongolia, which factors influence grazing mobility around camps, and how altitudinal migration benefits small livestock. We combined GPS tracking data of 19 small livestock herds monitored from September 2018 to April 2020 with remotely sensed climate and environmental data. We used general linear-mixed models to analyse variables influencing camp use duration and daily mobility patterns. To understand the importance of the altitudinal migration, we compared climatic conditions along the elevation gradient and looked at seasonal body weight changes of small livestock. We found that available plant biomass and season best explained camp use duration. Daily walking distance and maximum distance from camp increased with camp use duration. Pasture time increased with increasing biomass and rising temperatures. We conclude that herders in the Dzungarian Gobi have optimized pasture use by reacting to changes in biomass availability at landscape and local scale, and by embracing altitudinal migration. Flexibility in grazing mobility seems to have enabled local herder communities to practise sustainable pasture use. Maintaining this mobility will most likely be the best strategy to deal with environmental change under the current climate change scenarios.
Perceived social support and its relationship with self-regulated learning, goal orientation self-management, and academic achievement
Authors: Martínez-López Zeltia , Moran Valeria E. , Mayo Mª Emma , Villar Eva , Tinajero Carolina 
Published: October 2023

AbstractSelf-regulated learning is recognized as a core competence for academic success and life-long formation. The social context in which self-regulated learning develops and takes place is attracting growing interest. Using cross-sectional data from secondary education students (n = 561), we aimed to formulate explanatory arguments regarding the effect of social support on metacognitive knowledge, metacognitive and cognitive learning strategies, and academic achievement, considering the potential mediating role of goal orientation self-management. Structural Equation Modelling yielded a conceptually consistent and statistically satisfactory empirical model, explaining a moderate-high percentage of the variance in self-regulated learning and academic achievement. The results showed that perceived support from teachers and family positively predicted metacognitive knowledge, metacognitive and cognitive learning strategies, and mastery self-talk and negatively predicted work-avoidance self-talk. Moreover, mastery self-talk and work-avoidance self-talk directly and indirectly (through metacognitive knowledge) predicted academic achievement. Perceived social support is proposed as a marker of vulnerability/protection and as a resource for facing challenges in the academic context.
Does medication-related osteonecrosis of the jaw affect survival of patients with Multiple Myeloma?: Exploring a large single center database using artificial intelligence
Authors: Bittrich Max , Hetterich Regina , Solimando Antonio G. , Krebs Markus , Loda Sophia , Danhof Sophia , Anton Straub , Zhou Xiang , Kerscher Alexander , Beilhack Andreas , Kortüm K. Martin , Rasche Leo , Einsele Hermann , Knop Stefan , Hartmann Stefan 
Published: October 2023

AbstractIn addition to randomized clinical trials, consideration of Real-World Evidence is necessary for mirroring clinical reality. However, processing such evidence for large numbers of patients often requires considerable time and effort. This is particularly true for rare tumor diseases such as multiple myeloma (MM) or for adverse effects that occur even more rarely. In such cases, artificial intelligence is able to efficiently detect patients with rare conditions. One of these rare adverse events, and the most discussed, following bone protective treatment in MM is medication-related osteonecrosis of the jaw (MRONJ). The association of bone protective treatment to MM outcome has been intensively studied. However, the impact of MRONJ resulting from such treatment on MM prognosis and outcome is poorly understood. In this retrospective study, we therefore investigated the long-term effects of MRONJ. We used natural language processing (NLP) to screen individual data of 2389 MM patients to find 50 out of 52 patients with MRONJ matching our inclusion criteria. To further improve data quality, we then performed propensity score matching. In comparison to MM patients without MRONJ, we found a significantly longer overall survival (median 126 vs. 86 months) despite slightly worse clinical features.
Environmental controls on seedling establishment in a boreal forest: implications for Scots pine regeneration in continuous cover forestry
Authors: Häggström Bodil , Gundale Michael J. , Nordin Annika 
Published: October 2023

AbstractIn nutrient poor and dry forest sites common to northern Scandinavia, Scots pine (Pinus sylvestris L.) is the most common species both in managed and natural forests. However, Scots pine is sensitive to competition during establishment. Harvesting of all trees within a given area, i.e., clear-cutting, liberates regenerating seedlings from competition with mature trees. However, recently, clear-cut-free or continuous cover forestry has been the subject of substantial debate. When choosing a management method, it is important to recognize how competitive interactions direct the success of Scots pine regeneration. We studied Scots pine regeneration at three environments: beneath the canopy of mature trees, at the canopy edge in full sunlight, and distant from the canopy with no influence of mature trees. We imposed three treatments in each of these environments: root isolation (i.e., trenching), nitrogen (N) fertilization, and control plots. Root isolation enhanced seedling performance under the canopy of mature trees. Nitrogen fertilization enhanced seedling performance to a greater extent in the clear-cut than at the forest edge. However, N fertilization had no effect under the canopy. In the N-fertilized plots, we measured higher N content in the soil under the canopy than in the open environments, indicating that not all excess N was obtained by the mature trees. N-uptake might have been limited by competition for water in the N-fertilized plots. Our results suggest that belowground competition limits the success of regeneration of Scots pine. However, N fertilization presents a tool to compensate for underground competition along canopy edges.
Dissecting the continuum and unravelling the phylogeographic knot of plastid DNA in European white oaks (Quercus sect. Quercus): ancient signatures and multiple diversity reservoirs
Authors: Fortini Paola , Di Pietro Romeo , Proietti Elisa , Cardoni Simone , Quaranta Luca , Simeone Marco Cosimo 
Published: October 2023

AbstractAvailable knowledge on the European white oaks (Quercus, sect. Quercus) plastome still exhibits large gaps, mostly in respect of detailed phylogeny and information from southern Europe and adjacent Near East. We investigated DNA sequence polymorphism at two plastid loci on 270 individuals representing 13 white oak species/taxa and retrieved several hundred sequences of the same two DNA regions from GenBank to fill the above gaps, and contribute to a better understanding of white oak diversity and evolution. The modern European sect. Quercus species exhibits a poorly differentiated plastid DNA, despite its current highly diversified taxonomy. Twenty-nine haplotypes were identified across the Euro-Mediterranean and Near East regions, including two ancestral variants that are westerly and south-easterly partitioned. Other high- and low-frequency haplotypes also showed a well-structured geographic distribution consistent with the current phytogeographic framework of the European continent. The climatic and geological events that characterized the end of the Tertiary and Quaternary periods played a crucial role in triggering haplotype mixing, isolation, and in offering niche opportunities for more recent diversification. Euro-Mediterranean southern territories host a high and as yet poorly studied genetic variation; the role of the Italian Peninsula as a crossroad and threshold for haplotype diversity and distribution clearly emerges from this study.
Effects of digital skills and other individual factors on retirement decision-making and their gender differences
Authors: Lakomý Martin 
Published: October 2023

AbstractIncreasing the pension age as a dominant solution to population ageing does not bring desirable outcomes, if not accompanied by other essential measures in lifelong learning and fighting age discrimination. Moreover, rapid digitalisation and automation in the labour market bring additional uncertainties for the growing group of older workers. The analysis is based on the SHARE data from Waves 5, 6, and 7 and examines predictors of retirement intentions by two different estimation methods. While digital skills are positively associated with a willingness to stay in the labour market in the random-effect modelling, fixed-effects regression shows no correlation between digital skills and retirement intentions. This difference means that digital skills do not correlate with retirement intentions once we control for time-invariant individual characteristics. Thus, increasing ICT literacy among older workers can have a very limited potential for extending working lives. In contrast to this result, starting to be self-employed, health improvement, having an additional grandchild, and losing a partner increase the willingness to work longer. The study identifies the factors shaping retirement intentions, which should be reflected in any effective social policy.
Consumer’s perception and acceptance of lumpfish used in salmon cages
Authors: Thong Nguyen Tien , Ngoc Quach Thi Khanh , Voldnes Gøril 
Published: October 2023

AbstractLumpfish (Cyclopterus lumpus) are used as cleaner fish in salmon aquaculture to treat sea lice. However, after 18–24 months and reaching 0.4–0.6 kg, the fish is removed from the salmon cage and usually discarded, which raises social, economic, and environmental challenges, as well as ethical concerns. This paper assesses the viability of marketing lumpfish as food by exploring possible products that can be made from the fish in Vietnamese cuisine, and understanding the stakeholder’s perception and acceptance of the fish. We used a customer co-creation method to investigate market potential, sending a sample of 45 kg of frozen and whole lumpfish from Norway to Vietnam. Researchers, industrial stakeholders, restaurant chefs, and household consumers collaborated to discuss, process, cook, and taste the fish, and the evaluations were assessed before and after consumption. More than 10 Vietnamese dishes were identified as possible use for lumpfish, including grilled, fried, sour soup, hotpot, and several value-added products. Household consumers and restaurant buyers evaluated the fish positively in terms of sensory quality (taste, color, flavor, size, and texture), but the rough skin and sharp thorn are negative aspects. Individual consumers accept the fish and were willing to buy it if the price is reasonable. In contrast, industrial stakeholders evaluated the lumpfish less favorably, citing its soft and mushy texture, sticky smell, and very low fillet-recovery-ratio (only 15.9% of skinless fillet and 16.7% of kama can be obtained from whole-defrosted lumpfish). They also found that the taste of the fish was not delicious and bitter in some value-added products. In addition, this study found that the information relating to lumpfish as a cleaner fish is not an issue in the Vietnamese context.
Association of LDL-C level with neoatherosclerosis and plaque vulnerability in patients with late restenosis: an optical coherence tomography study
Authors: Liu Zhijiang , Deng Chancui , Zhao Ranzun , Xu Guanxue , Bai Zhixun , Wang Zhenglong , Zhang Wei , Ma Yi , Hu Xingwei , Jin Caide , Chen Panke , Ma Shuai , Shi Bei 
Published: October 2023

AbstractNeoatherosclerosis (NA) is a significant contributor to late stent failure; however, predictors of late in-stent restenosis (ISR) with NA have not been systematically reported. This study aimed to identify predictors of NA incidence and plaque vulnerability in patients with late ISR and the role of low-density lipoprotein cholesterol (LDL-C) levels in this process. A total of 216 patients with 216 lesions who underwent optical coherence tomography (OCT) before interventional procedure for late drug-eluting stent ISR were enrolled and divided into NA and non-NA groups based on OCT findings. Results showed that higher LDL-C levels were associated with NA, thin-cap fibroatheroma (TCFA), intimal disruption, plaque erosion, and thrombosis. Multivariate regression analysis revealed that the LDL-C level was an independent risk factor for NA and TCFA. The LDL-C levels exhibited a significant predictive value for NA and TCFA, surpassing other factors such as stent age and other lipid types. In conclusion, a high LDL-C level is an independent predictor of NA incidence and plaque vulnerability in patients with late ISR.