bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bilateral simultaneous sampling of the cavernous and inferior petrosal sinuses in the differential diagnosis of Cushing’s disease
Authors: Rudakov I. A. , Savello A. V. , Cherebillo V. Yu. , Paltsev A. A. , Tsoy U. A. , Grineva E. N. , Kuritsyna N. V. 
Published: February 2024

Background. Currently, the “gold standard” of differential diagnosis of Cushing’s disease is inferior petrosal sinus sampling and measurement of the adenocorticotropic hormone (ACTH) level. The studied literature data indicate a wide variability in the sensitivity and specificity of inferior petrosal sinus sampling in the range of 85–100 and 67–100 %, respectively, which can lead to an erroneous diagnosis of the source of ACTH hyperproduction and, as a consequence, to incorrect and untimely treatment.Aim.To improve the results of differential diagnosis of Cushing»s disease by using bilateral simultaneous sampling of the cavernous and inferior petrosal sinuses.Materials and methods. Cohort single-center retro/prospective study of 70 patients with confirmed ACTH-dependent Cushing’s syndrome. For the purpose of differential diagnosis, a number of indicators were calculated: central-peripheral ratio, prolactin-normalized ACTH ratio, successful catheterization. Sampling results were evaluated in comparison with contrast-enhanced pituitary magnetic resonance imaging data and intraoperative data.Results. The study of the central-peripheral ratio showed the need to assess it simultaneously at the level of the cavernous and inferior petrosal sinuses. This approach makes it possible to significantly increase the sensitivity and specificity of the applied gradient to 93.1 and 85.7 %, respectively. Prolactin-normalized ACTH ratio is a second line predictor in the differential diagnosis of Cushing’s disease with sensitivity and specificity reaching 94.7 and 28.6 %, respectively. The gradient of successful catheterization is a reflection of possible hemodynamic features of a particular sinus, does not serve as an indicator of the correct positioning of microcatheters in the vascular bed.Conclusion. Bilateral simultaneous sampling of the cavernous and inferior petrosal sinuses is an effective method of differential diagnosis of Cushing’s disease and ectopic ACTH-dependent syndrome.
The role of quick pain management treatments in clinical physiotherapy practice in India: Advantages, disadvantages, and recommendations
Authors: Thiyagarajan Alagappan 
Published: February 2024

Quick pain management treatments in physiotherapy play a vital role in addressing immediate musculoskeletal or movement-related issues, providing short-term relief to patients. This article explores the reasons why patients seek quick treatments, outlines their advantages and disadvantages, and provides recommendations for a more comprehensive physiotherapy approach. The content is based on a synthesis of current literature, including scholarly articles, clinical guidelines, and textbooks in physiotherapy, pain management, and rehabilitation. Patients often seek quick treatments for reasons such as immediate relief from pain and discomfort, convenience, shorter duration, cost considerations, a preference for rapid solutions, and concerns about more invasive procedures. However, relying solely on quick treatments may mask symptoms, delay overall recovery, and increase the risk of recurrent problems. The article emphasizes the importance of education, setting realistic expectations, developing comprehensive treatment plans, empowering patients, continuous monitoring and adjustment, evidence-based practice, addressing patient concerns, and promoting long-term health goals. Physiotherapists and patients should collaborate to strike a balance between quick treatments for short-term relief and a more comprehensive approach for long-term recovery and prevention. The recommendations provided aim to enhance patient understanding, engagement, and satisfaction, ultimately contributing to improved overall outcomes in physiotherapy.
A Scoping Review of Children, Empowerment and Smartphone Technology Regarding Social Construction Theory with the Aim of Increasing Self-Direction in Democracies
Authors: Nash Carol 
Published: February 2024

Children—Dependents in Social Construction Theory—are assessed within democracies regarding their ability to self-direct their behavior concerning their associated society. In this regard, childhood represents a lack of self-direction, a life period when people require the guidance and protection of adults. The assumed necessity of adults supervising children in democracies requires substantial social resources, reducing the self-direction of those charged with overseeing children. Given that self-direction defines the optimal experience of people within democratic society, finding ways to increase the self-direction of children is an individual and a social benefit. In this regard, smartphones have improved self-direction in children. How children have become empowered to self-direct their lives with smartphone use considering Social Construction Theory—as Advantaged, Contenders, or Deviants—is the focus of a scoping review conducted on “children, empowerment, smartphones” of the following databases: OVID, JSTOR, ProQuest, PubMed, Scopus, and Web of Science. The result is that children permitted to self-direct their activities aided by smartphone technology have comparable social behavior to adults positioned as Advantaged, Contenders, or Deviants and, as such they should be encouraged to utilize smartphone technology to improve their self-direction, as doing so will augment individual and caregiver self-direction, providing increased social benefit.
Symptomatic Coracoid Fracture Nonunion Treated with Arthroscopic Reduction and Suture Anchor Fixation
Authors: Brusalis Christopher M. , Mizels Joshua , Moverman Michael A. , Chalmers Peter N. 
Published: February 2024

Case:
A 15-year-old female rock climber presented with a traumatic coracoid process fracture of her dominant upper extremity that failed extensive nonoperative treatment. She was treated successfully by arthroscopic reduction and suture anchor fixation.

Conclusion:
A novel surgical technique for coracoid fracture that combines arthroscopic reduction with suture anchor fixation can result in expeditious and durable clinical improvement in a young, high-demand athlete.
The introduction of allergenic foods to the infant diet in a UK cohort: the impact of family history of allergy
Authors: Helps Suzannah , Mancz Gilly , Dean Taraneth 
Published: February 2024

Abstract
Background/Objective: To describe the introduction of highly allergenic foods in a UK population sample, and to determine whether the introduction of highly allergenic foods differed in infants with family history of allergy.
Subjects/Methods: A population birth cohort study recruited eligible pregnant women while they were attending an antenatal ultrasound clinic appointment at a UK city hospital. Parental-reported family history of allergy and infant diet was collected through structured interviews at recruitment and postal questionnaires. Parents reported on their infants’ diet at around 6 months (n = 216), around 12 months (n = 193) and around 24 months of age (n = 139).
Results: Most highly allergenic foods were introduced to infants at around 6-9 months. However, nut and egg were introduced much later, and 21% of children had not been exposed to egg and 35% of infants had not been exposed to nuts by 12 months. Infants with a family history of allergy were introduced to highly allergenic foods at a similar time to other infants but were more likely to have diets that avoided foods due to allergy than other infants (most commonly dairy, soya, egg and nuts).
Conclusions: As many parents delayed the introduction of egg and nuts beyond one year of age and infants with a family history of allergy were more likely to have diets that avoided foods due to allergy, these behaviours might affect the development of allergies in infants and could be a modifiable risk factor for allergy development.
Chemical Elements Analysis of Arjuno-Welirang Igneous Rocks
Authors: Zakly Hanif 'Izzuddin , Zulaikah Siti , Hapsoro Cahyo Aji , Maulida Shofi , Hasan Muhammad Fathur Rouf 
Published: February 2024

Abstract

Mount of Arjuno-Welirang has a geological structure consisting of volcanic breccias, lava, tuff and tuff breccias. This study aims to determine the chemical element content of the igneous rocks constructed on Mount Arjuno-Welirang. X-ray fluorescence (XRF) analysis of 7 samples showed the presence of Al, Si, P, K, Ca, Ti, V, Cr, Mn, Fe, Cu, Zn, Sr, Ba, Eu, and Re. The dominant elements (Wt% >10%) from high concentrations are Si, Al, Ca, and Fe. In addition, we also found Rare Earth Element (REE) Europium (Eu) content with an average of 0.23Wt%. SiO2 compound is larger than the Bromo-Semeru volcanic material, while K2O is larger than the Semeru volcanic material and smaller than Bromo. Meanwhile, the Fe2O3 compound is taller than that of Bromo-Semeru. Based on the Hutchinson formula, the depth of the magma source is determined in the range of ± 147.7 km to ± 225.1 km below the surface. Depth data also significantly affect several oxide compounds, such as K2O, V2O5, and ZnO, with correlations of .942**, − .747*, and − .936 **, respectively. The significant correlation shown is only the correlation with K2O, which offers a considerable correlation relationship with a positive trend.
Public Health Among People Experiencing Homelessness during COVID-19
Authors: Pearson Michael , Monico Carmen 
Published: February 2024

Abstract

The COVID-19 pandemic magnified organizational and universal issues adversely affecting health among many including those experiencing homelessness. Among homeless populations, the high-risk nature of COVID-19 challenged access to treatment, disrupts access to housing and security, and it aggravated social disparities such as employment loss, housing access and extended homelessness. This study looks at the need to identify and implement mitigating strategies to reduce and address communicable disease within shelter environments. This study utilizes staff and client surveys through Qualtrics to document the experiences of clients and staff of a homeless shelter in Greensboro during COVID-19 and when entering service delivery. The study gauged participant perceptions regarding the shelter’s public health response, their access to health and housing resources, and access to treatment. In addition, it identified the level of impact of the pandemic on shelter services and sense of safety. The study found that multiple intersecting factors influenced disease spread, such as, living conditions, treatment adherence, and risky behavior. This research shows that to adequately provide services, to ensure safety and reduce outbreaks, mitigating strategies such as onsite screening and access to treatment and care are essential. Data collected shows that method of service delivery to populations experiencing homelessness is an essential mitigating strategy and helps address risk and barriers within homelessness.
Quali-quantitative Assessment of Solid Waste Generated at Ifgoiano- Rio Verde
Authors: de Oliveira Marcos Fernandes , Couto Bruno de Oliveira Costa , junior Edio Damásio da Silva 
Published: February 2024

Abstract
On a university campus, the diversity of types of waste is substantially relevant, as there are theoretical and practical classes, laboratory and field tests, maintenance of furniture, utensils and installations, in addition to a pulsating community that uses the campus space intensively for much of its day, including its food. In view of the above, this study aimed to carry out a qualitative and quantitative inventory of the solid waste generated on the premises of the Instituto Federal Goiano - Campus Rio Verde, using the methodological procedures suggested by NBR 10004/2004 with adaptations for the campus. Nine collection points were evaluated, listed from one to nine, three of which were voluntary drop-off points (PEVs), identified as 1, 5 and 7. The remaining six were distributed around the campus in areas close to laboratories and classrooms. The evaluation period ran from February to October 2022, with two monthly collections, always on days before the municipal public service's known collection times. The research was divided into two stages, the first of which was to apply questionnaires assessing consumption and waste generation, surveying the type of material generated, the frequency of disposal, the destination of this material and forms of packaging for segregation. This was followed by a gravimetric survey of nine identified and mapped collection points. The aim was to identify the profile of waste-producing agents, the amount generated, segregated and sent for recycling, what is sent to the municipal landfill and its possibility of recovery. A total of 5,008.34 kg of solid waste was collected, of which 23.4% was thermoplastics, 11.8% cardboard, 13% food waste, and 28.9% was collected at voluntary drop-off points by recycling cooperatives. The study also found that at points 2, 3, 6 and 8, the volumes of thermoplastics and cardboard are higher than those disposed of at the PEVs, demonstrating that although there is a perception of the importance of recycling, it is still deficient. projecting for one year based on the amount found, in the area used by the Campus, an amount of 0.22t/inhab/year of solid waste generation was obtained
Identification of a HAGLR/miR-338-3p/GALNT2 regulatory axis in laryngocarcinoma based on bioinformatics analysis
Authors: Liu Hao , JIang Qichuan , Wang Yijie , Qian Ming 
Published: February 2024

Abstract
GALNT2 is associated with the occurrence and development of many tumors, but its role in laryngeal carcinoma has not been studied. This study used TCGA and GEO databases to analyze GALNT2 expression in laryngeal cancer and adjacent tissues. Western blot, immunohistochemistry, and RT-qPCR were used to validate results. Survival analysis assessed the impact of GALNT2 expression on patient prognosis. KEGG and GSEA enrichment analyses identified biological pathways associated with GALNT2. CIBERSORT algorithm examined the effect of GALNT2 on tumor immune cell infiltration. ENCORI database built a ceRNA network. TIMER2.0 database studied GALNT2 expression in various tumors. The results find that GALNT2 is highly expressed in laryngeal cancer patients and has prognostic implications. Enrichment analysis showed that GALNT2 is involved in various carcinogenic pathways. GALNT2 expression levels were significantly correlated with immune cell and immune checkpoint content in the tumor microenvironment. The HAGLR/miR-338-3p/GALNT2 regulatory axis may affect laryngeal cancer development. GALNT2 expression levels also differed significantly among other tumor types, as shown in our pan-cancer analysis. GALNT2 is a significant factor in the prognosis and immune cell infiltration of laryngeal cancer patients, indicating its potential as a useful prognostic marker for laryngeal cancer.
The Carboxymethyl cellulose-based slimming gel containing nano-liposomes loaded with chili pepper and ginger extracts: As destroyer jelly of obesity
Authors: Jalilian Saba , Arkan Elham , Alvandi Hosna , Aghaz Faranak 
Published: February 2024

Abstract
Obesity is a major global health issue that negatively impacts individuals and societies. It can lead to obesity-related illnesses, reduced quality of life, and even death. Diet, exercise, and surgery are basic solutions to overcome obesity, but due to the long duration of the treatment and sometimes the lack of appropriate results, create limitations. In this study for the first time, Carboxy methyl cellulose-based slimming gel containing nanoliposomes loaded chili pepper and ginger extracts (CMC-sliming gel containing Chi/G-NLPs), as bioactive fat burners, has been investigated for potential application in the fat burning and weight loss. Finally produced Nano-Gel (Ch/G-NLPs-CMC) were confirmed through scanning electron microscopy (SEM), Fourier-transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS), Zeta potential, in vitro release profile and in vitro skin absorption assays. In vitro skin absorption assay showed 30% after 2.5 h use of CMC-sliming gel containing Chi/G-NLPs. In addition, the CMC-sliming gel containing Chi/G-NLPs size was 156 nm. In vitro release behavior of CMC-sliming gel containing Chi/G-NLPs showed slow control released at 24 h then a sharp peak release observed at 48 h. Our result confirmed the synergistic effect of chili pepper and ginger in the Nano-Gel platform, as a novel topical treatment, for eliminating local fat and a destroyer jelly of obesity.
Examining the role of personality functioning in a hierarchical taxonomy of psychopathology using two years of ambulatory assessed data
Authors: Kerber André , Ehrenthal Johannes , Zimmermann Johannes , Remmers Carina , Nolte Tobias , Wendt Leon , Heim Phileas , Müller Sascha , Beintner Ina , Knaevelsrud Christine 
Published: February 2024

Abstract

The Hierarchical Taxonomy of Psychopathology (HiTOP) arranges phenotypes of mental disorders based on empirical covariation, ranging from narrowly defined symptoms to higher-order spectra of psychopathology. Since the introduction of personality functioning (PF) in DSM-5 and ICD-11, several studies have identified PF as a transdiagnostic predictor of psychopathology. However, the role of PF in the HiTOP classification system has not been systematically examined. This study investigates how PF can be integrated into HiTOP, whether PF accounts for transdiagnostic variance captured in higher-order spectra, and how its predictive value for affective well-being (AWB) and psychosocial impairment (PSI) compares to the predictive value of specific psychopathology. To this end, we examined two years of ambulatory assessed data on psychopathology, PF, PSI, and AWB of N = 27 173 users of a mental health app. Results of bass-ackwards analyses largely aligned with the current HiTOP working model. Using bifactor modeling, aspects of PF were identified to capture most of the internalizing, thought disorder, and externalizing higher order factor variance. In longitudinal prediction analyses employing bifactor-(S-1) modeling, PF explained 58.6% and 30.6% of one-year variance and 33.1% and 23.2% of two-year variance in ambulatory assessed PSI and AWB, respectively. Results indicate that personality functioning may largely account for transdiagnostic variance captured in the higher-order components in HiTOP as well as longitudinal outcomes of PSI and AWB. Clinicians and their patients may benefit from assessing PF aspects such as identity problems or internal relationship models in a broad range of mental disorders. Further, incorporating measures of PF may advance research in biological psychiatry by providing empirically sound phenotypes.
Determination of Volatile Components in Lemon Peels at different ripe stages
Authors: li chunxiu 
Published: February 2024

Abstract
Volatiles are important components determining fruit flavor and consumer preferences, and also essential indicators affecting the industrial processing value of fruits. Volatiles in peels of meyer lemon and rough lemon at five harvest stages were characterized through headspace solid-phase microextraction combined with gas chromatography mass spectrometry. 68 volatiles were identified including seven chemical sorts. Among them fifty-one significant varied with fruit ripening.Monoterpenes increased while sesquiterpenes decreased with fruit ripening. D-limonene and wasβ-bisabolene the most riched monoterpene and sesquiterpene respectly.Among oxygenated volatile compounds, aldehydes, alcohols, and others were much abundant than esters and ketones,which in two cultivars generallly decreased with fruit ripenging. Thymol and α-terpineol were the most aboudant oxygenated volatiles in meyer lemon and rough lemon respectively, both of them reached the highest level at first harvest period.Meyer lemon peels especially the immature one was a good raw material for extracting thymol which is an important food spices.
Infectious cavernous sinus thrombosis complicated with meningitis, trigeminal neuralgia and denervation change: a case report
Authors: Chen Yu-Chun , Lai Hsin-Yi , Lee Yuarn-Jang , Kevin Li-Chun Hsieh 
Published: February 2024

Abstract

Background:
Cavernous sinus thrombosis is a rare and potentially life-threatening condition that can have various causes. Symptoms of this disorder include headache, reduced visual acuity, focal neurological symptoms, seizures, and cranial nerve deficits, depending on the structures involved. Although rare, sensory and motor trigeminal neuropathy can be an initial presentation of cavernous sinus thrombosis.
Case presentation:
A 67-year-old female presented with trigeminal neuralgia, followed by tinnitus, vertigo, and trismus. Upon arrival at the emergency department, she also exhibited fever, dizziness, and neck stiffness. The patient had received a tooth implant months before experiencing these symptoms. Initial magnetic resonance imaging revealed homogeneously increased T2 signal and contrast enhancement of bilateral temporalis and masseter muscles, indicating denervation changes of the bilateral trigeminal nerves. Imaging features of basal meningitis and cavernous sinus thrombosis were also noted. Lumbar puncture and laboratory tests were performed, and blood culture revealed Streptococcus intermedius. The patient was diagnosed with meningitis and cavernous sinus thrombosis, complicated by trigeminal neuropathy. She was treated with vancomycin and amoxicillin, and her clinical symptoms greatly improved. Follow-up magnetic resonance imaging studies showed regression of the trigeminal denervation signals.
Conclusion:
This case report highlights a rare presentation of cavernous sinus thrombosis and basal meningitis, where the initial symptom was trigeminal neuropathy. Denervation changes of the bilateral trigeminal nerves were detected in the MRI study. Therefore, clinicians should be aware that trigeminal neuropathy may be the earliest manifestation of cavernous sinus thrombosis. It is crucial to consider secondary causes of this life-threatening disease to ensure prompt diagnosis and management.
Contactless temperature measurements on FSWed joints in aluminium and magnesium alloys
Authors: Bianchi Iacopo , Forcellese Archimede , MANCIA TOMMASO , Mignanelli Chiara 
Published: February 2024

Abstract
IIn this work, the heating distribution on similar and dissimilar friction stir welded joints in aluminium and magnesium alloys sheets was studied. Friction Stir Welding processes were performed using constant rotational and welding speeds of 1500 rpm and 60 mm/min, respectively. In order to obtain a completely non-intrusive and temperature monitoring measurement technique, a contactless method based on infrared thermography was used to remotely analyse the temperature distribution over the welded area, near the tool during the Friction Stir Welding process. It was observed that the mechanical properties of joints are strictly related to the heat distribution. This system was used both to experimentally evaluate the temperature on the top surface of the joints and as it is able to detect the presence of flow defects with a contactless and non-destructive method, demonstrating the effectiveness of this measuring system as a diagnostic tool for the online quality control of welded joints.