bluuebunny/crossref_metadata_2025_split huggingface dataset:
Usefulness of capsule endoscopy for small intestinal obstruction: a dual-center prospective observational study
Authors: Imai Makoto , Niikura Ryota , Yamada Atsuo , Suzuki Hirobumi , Nakada Ayako , Mitsuno Yuzo , Yamamoto Shinzo , Aoki Tomonori , Hayakawa Yoku , Kawai Takashi , Fujishiro Mitsuhiro 
Published: January 2024

Aim: To evaluate whether capsule endoscopy can identify causes of small intestinal obstruction and determine the appropriate patient population for capsule endoscopy.
Methods: In this prospective observational study, we performed a tag-less patency capsule endoscopy for patients with small intestinal obstruction. After confirming the patency of the small intestine, capsule endoscopy was performed using Pill Cam SB2. The study endpoint was recurrence of small intestinal obstruction within 1 year.
Results: Of the 31 study patients, 8 were excluded. The remaining 23 patients, including 13 with a history of surgery and 3 with band adhesions on contrast-enhanced CT, were analyzed. Subsequently, 18 of the 23 study patients underwent tag-less patency capsule endoscopy to evaluate the small intestinal patency. Capsule endoscopy revealed redness in six patients, erosions and ulcers in three patients, small intestinal diverticulum in one patient, and tumor in one patient. One patient with Meckel’s diverticulum and another with small intestinal ganglioneuroma underwent surgical resection. No recurrence of small intestinal obstruction was observed at 1 year.
Conclusion: This prospective observational study demonstrated that capsule endoscopy can determine the cause of small intestinal obstruction after the obstruction is relieved.
Acute psycho-physiological responses to submaximal constant-load cycling under intermittent hypoxia-hyperoxia vs. hypoxia-normoxia in young males
Authors: Behrendt Tom , Bielitzki Robert , Behrens Martin , Jahns Lina-Marie , Boersma Malte , Schega Lutz 
Published: January 2024

Abstract
Hypoxia and hyperoxia can affect the acute psycho-physiological response to exercise. Recording various perceptual responses to exercise is of particular importance for investigating behavioural changes to physical activity towards health, given that the perception of exercise-induced pain, discomfort or unpleasure, and a low level of exercise enjoyment are commonly associated with a low adherence to physical activity. Therefore, this study aimed to compare the acute perceptual (i.e., ratings of perceived motor fatigue, effort perception, perceived physical strain, affective valence, arousal, motivation to exercise, conflict to continue exercise, and activity enjoyment) and physiological responses (i.e., heart rate (HR), capillary blood lactate concentration (BLC), peripheral blood oxygenation (SpO2), total tissue (tHb) and oxygenated haemoglobin concentration (SmO2) of the vastus lateralis muscle) to 40 min constant-load cycling (60% peak oxygen uptake) under intermittent hypoxia-hyperoxia (IHHT), hypoxia-normoxia (IHT), and sustained normoxia (NOR) in young recreational active healthy males. No differences in the acute perceptual responses were found between conditions (p ≥ 0.059, ηp²≤0.18), while the physiological responses differed. Accordingly, SpO2 was higher during hyperoxia and normoxia in IHHT compared to IHT (p < 0.001, ηp²=0.91), respectively. Moreover, HR (p = 0.005, ηp²=0.33) and BLC (p = 0.033, ηp²=0.28) were higher during IHT compared to NOR. No differences between conditions were found for percentual changes in tHb and SmO2 of the vastus lateralis. These results suggest that replacing normoxic by hyperoxic reoxygenation-periods during submaximal constant-load cycling under intermittent hypoxia reduced the exercise-related physiological stress but had no effect on perceptual responses and perceived activity enjoyment in young recreational active healthy males.
Reducing dependence on peat for flower seedling cultivation through the use of unfermented bamboo particles as renewable resources
Authors: Lei Ting , Nie Jiao , Zhang Qing , Li Liu , Yang Hang , Zhu Junyao , Yang Lijuan , Li Jiani , Yu Xiaofang , Jiang Mingyan , Deng Xiaobing , Gao Suping 
Published: January 2024

Abstract

This study employed Bambusa emeiensis branches and leaves to prepare non-decomposing bamboo particles, which can serve as renewable resources in the plant cultivation industry. Experiments were conducted to assess the effect of the relative content of branches and leaves, the size, and the proportion of bamboo particles in the cultivation substrate on the growth of two flowers exhibiting distinct habitat preferences. The results indicated that the mixture ratio of branches and leaves in the substrate had a negligible impact on plant growth. The introduction of bamboo particles with a diameter between 0.5 and 1.0 mm to peat soil facilitated the growth of Ceratostigma willmottianum, whereas particles smaller than 0.5 mm proved more suitable for the growth of Plumbago auriculata. A substrate comprising 40% bamboo particles proved suitable for C. willmottianum, whereas P. auriculata exhibited better suitability to a substrate containing 60% bamboo particles. This discrepancy may stem from the alterations of the substrate’s physical and chemical properties that are determined by the bamboo particles' proportion. Consequently, additional research is necessary to ascertain the optimal quantity of bamboo particles for various plant species. Here we demonstrate that it has successfully created a renewable resource derived from B. emeiensis waste, which does not necessitate decomposition and has been implemented in soilless flower cultivation, thereby offering novel perspectives on land resource conservation.
Performance Evaluation of SC-FDMA in Fading Channels with PAPR, QAM, and RSSI Analysis
Authors: sharma Amol , Chauhan Ram Chandra Singh , Kaur Jaspreet 
Published: January 2024

Abstract
Wireless communication systems have evolved significantly, driven by diverse modulation techniques tailored to specific channel conditions, profoundly impacting overall performance. Achieving flawless data transmission with minimal errors hinges on employing modulation algorithms attuned to the communication channel's characteristics. Thus, power efficiency, bandwidth utilization, and error rate are crucial metrics for assessing modulation methods. M-ary Quadrature Amplitude Modulation (M-QAM) is a key player in wireless communication, especially in challenging fading channel conditions. This study extensively examines the Bit-Error-Rate (BER) performance of various M-QAM schemes across different channel scenarios, including AWGN, Rayleigh, Rician, and Nakagami-m fading channels. The Received Signal Strength Indicator (RSSI) is analyzed to evaluate signal strength and system performance. Moreover, the study delves into Single Carrier Frequency Division Multiple Access (SC-FDMA), an innovative uplink communication method within LTE. SC-FDMA stands out for its exceptional spectral efficiency, low bit error rate, and reduced peak-to-average power ratio (PAPR) compared to conventional OFDM. Through MATLAB simulations, the research assesses PAPR performance for SC-FDMA and OFDMA, exploring Distributed FDMA (DFDMA), Localized FDMA (LFDMA), and Interleaved FDMA (IFDMA) subcarrier assignment approaches. The findings indicate that IFDMA exhibits lower PAPR in SC-FDMA, while LFDMA outperforms IFDMA in Symbol Error Rate (SER) performance.
A framework for simulating genotype by environment interaction using multiplicative models
Authors: Bančič Jon , Gorjanc Gregor , Tolhurst Daniel 
Published: January 2024

Abstract

This paper develops a general framework for simulating genotype by environment interaction (GEI) using multiplicative models. Many stages of plant breeding are complicated by GEI, from the selection of potential parents to the development of improved genotypes for release to growers. Despite its importance, however, current plant breeding simulations do not adequately capture the complexity of GEI because they either use unrealistic models to simulate it or they ignore it completely. The framework developed in this paper simulates the two main components of GEI, that is non-crossover and crossover interaction, using the class of multiplicative models. The framework is demonstrated using two working examples supported by R code. The first example embeds the framework into a linear mixed model to generate MET datasets with low, moderate or high GEI, which are then used to compare various statistical models widely used in plant breeding. The results show that the prediction accuracy of all models increases as the level of GEI decreases or the number of sampled environments increases. The second example integrates the framework into a breeding programme simulation to compare genomic and phenotypic selection strategies over time. The results show that genomic selection outperforms phenotypic selection by 1.4−1.8 times, depending on the level of GEI. These examples demonstrate how the new framework can be used to generate realistic MET datasets and model plant breeding programmes that better reflect the complexity of real-world settings, making it a valuable tool for breeders to optimize their breeding programmes. The framework also has broader applications beyond plant breeding, including animal, aquaculture and tree breeding as well as other analysis comparison settings.
Multi-Objective Optimization of Microcellular Injection Molding Process Parameters to reduce energy consumption and improve product quality
Authors: Guo Wei , Lu Tongyuan , Zeng Fankun , Zhou Xiaoyu , Li Wei , Yuan Huan , Meng ZhengHua 
Published: January 2024

Abstract

The microcellular injection molding (MIM) process is widely used in the manufacture of automotive parts to achieve vehicle lightweighting. Due to the complex conditions of MIM process, it is easy to cause high energy consumption and warpage deformation of product. To achieve low energy consumption, lightweight, and high-quality production of MIM products, this study selected the automotive door interior panel as the research object, and the parameters of the MIM process were optimized by comprehensively taking into account the production energy consumption, weight, and warpage. In particular, the training sample database was created using Latin hypercube sampling, and the optimal neural network prediction model was established and selected considering the nonlinear relationship between process parameters and energy consumption, quality and warpage. Then, the NSGA-II algorithm and the fuzzy decision based on the critic method were used to identify the optimal process parameters. Finally, the finite element simulation of automobile door interior panels verifies the exactitude of the optimization process. The optimized energy consumption, weight, and warpage are 89.54 kJ, 169.5 g, and 2.807 mm, respectively, and have decreased by 16.78%, 2.88%, and 8.48% when compared with the best results under the combination of traditional process parameters.
Prediction of morbidity and mortality after thoracoabdominal esophageal surgery
Authors: Nilsson Erik , Olsén Monika Fagevik , Boström Petrus , Trolle Ulrika , Eriksson Frances , Becovic Suada , Hermansson Michael 
Published: January 2024

Abstract
Background Complications after esophagectomy result in higher morbidity and mortality, longer hospital stays and lower quality of life. Unfortunately, we have insufficient knowledge of which patients will tolerate the combination of strenuous oncological therapy and major surgery. This study was designed to evaluate whether additional physical tests, apart from standard preoperative workups, could help identify high-risk patients regarding esophageal cancer surgery.Methods A total of 88 patients due to undergo esophagectomy for esophageal cancer were enrolled. In addition to the mandatory physical examinations, seven additional physical therapy tests were carried out within 10 days prior to surgery. CT scans were examined by an experienced radiologist to determine whether patients suffered from sarcopenia. Perioperative data and times of death were gathered from a national register. The primary outcome was the presence of any severe postoperative complication, classified as Clavien-Dindo ≥3, with specific complications as secondary outcomes, and associations between preoperative test performance and complications were examined.Results Patients with severe complications had preoperatively performed significantly worse on peak expiratory flow tests (p = 0.013). Patients suffering from anastomotic leakage had shown significantly worse performance on cardiopulmonary exercise testing, whereas the results from shoulder abduction tests were significantly lower in patients who later suffered from pneumonia (p = 0.034 and p = 0.043, respectively).Conclusion More extensive preoperative physical examination tests could potentially aid in identifying patients with an increased risk of postoperative complications. Further studies are needed on the subject to corroborate these findings and evaluate their clinical use.
Hematocrit control and thrombotic risk in patients with polycythemia vera treated with ruxolitinib in clinical practice
Authors: Chojecki Aleksander , Boselli Danielle , Dortilus Allison , Hamadeh Issam , Begley Stephanie , Chen Tommy , Bose Rupali , Podoltsev Nikolai , Zeidan Amer , Balmaceda Nicole Baranda , Yacoub Abdulraheem , Ai Jing , Knight Thomas Gregory , Ragon Brittany Knick , Shah Nilay , Sanikommu Srinivasa Reddy , Symanowski James , Mesa Ruben , Grunwald Michael 
Published: January 2024

Abstract

Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by unregulated red blood cell production resulting in elevated hemoglobin (HGB) and/or hematocrit (HCT). Patients often have clinical symptoms such as fatigue, pruritus, and painful splenomegaly but are also at increased risk of thrombosis, both venous and arterial. Ruxolitinib, a selective JAK inhibitor, is approved by the US Food and Drug Administration as second-line cytoreductive treatment after intolerance or inadequate response to hydroxyurea. Though ruxolitinib has been widely used in this setting, limited data exist in the literature on ruxolitinib treatment patterns and outcomes among patients with PV in routine clinical practice. We report a retrospective, observational, cohort study of patients treated for PV with ruxolitinib across three US centers (academic and regional practice) from December 2014-December 2019. We identified 69 patients with a median follow-up was 3.7 years (95% CI, 2.9 to 4.4). Our data demonstrate very high rates of HCT control (88% of patients by three months and 89% by six months); few patients required dose adjustments or suspension during the study period. No arterial thromboses were observed and we found that one patient had a thrombotic event in the setting of a second malignancy. We also found that 28% of patients initiated ruxolitinib as a result of poorly controlled platelet counts, second only to hydroxyurea intolerance (46%). In clinical practice, ruxolitinib continues to be effective in controlling HCT after three and six months of treatment in patients with low thrombotic risk.
Enhancing Real-time Target Detection in Smart Cities: YOLOv8-DSAF Insights
Authors: Li Yihong , Huang Yanrong , Tao Qi 
Published: January 2024

Abstract

With the global rise of smart city construction, target detection technology plays a crucial role in optimizing urban functions and improving the quality of life. However, existing target detection technologies still have shortcomings in terms of accuracy, real-time performance, and adaptability. To address this challenge, this study proposes an innovative target detection model. Our model adopts the structure of YOLOv8-DSAF. The model comprises three key modules: Depthwise Separable Convolution (DSConv), Dual-Path Attention Gate module (DPAG), and Feature Enhancement Module (FEM). Firstly, DSConv technology optimizes computational complexity, enabling real-time target detection within limited hardware resources. Secondly, the DPAG module introduces a dual-channel attention mechanism, allowing the model to selectively focus on crucial areas, thereby improving detection accuracy in high-dynamic traffic scenarios. Finally, the FEM module highlights crucial features to prevent their loss, further enhancing detection accuracy. Experimental results on the KITTI V and Cityscapes datasets indicate that our model outperforms the YOLOv8 model. This suggests that in complex urban traffic scenarios, our model exhibits superior performance with higher detection accuracy and adaptability. We believe that this innovative model will significantly propel the development of smart cities and advance target detection technology.
Serum Beclin-1 Levels in Patients With Preeclampsia: a Case Control Study
Authors: Imamoglu Metehan , Ekici Huseyin , Okmen Firat , Hortu Ismet , Yeniel Ahmet Ozgur 
Published: January 2024

Abstract
Background
Autophagy is an intracellular catabolic degradation process in cellular physiology. Beclin-1 is a protein that regulates this process and is used as a marker of this process in tissues. We evaluated the serum beclin-1 levels in pregnancies complicated by preeclampsia.
Methods
41 women with preeclampsia and 47 women with uncomplicated pregnancies were enrolled in the study. Maternal serum levels of beclin-1 were measured by using enzyme-linked immunosorbent assay kit (ELISA). Demographic data and several other parameters were also recorded and analyzed.
Results
Mean serum beclin-1 levels were lower in patients with preeclampsia and this difference was statistically significant (6.32±.65 vs 4.05±.67, p<0.05). Urea and creatinine levels were significantly higher in patients with preeclampsia (p<0.005). Beclin-1 levels were found as statistically different in early and late preeclampsia groups as well, again revealing lower mean beclin-1 levels in preeclamptic patients (p: 0.000, p: 0.000 respectively)
Conclusions
To the best of our knowledge, this study is the first to investigate the serum beclin-1 levels in patients with preeclampsia and demonstrated the altered serum beclin-1 levels in preeclamptic patients. This finding suggests that serum beclin-1 levels also reflect the altered autophagy process in preeclampsia and can be utilized as a clinical tool.
How is Intimate Partner Violence associated with Sexually Transmitted Infections and Reproductive Tract Infections? A Cross-Sectional Study with Afghan Refugee Women in Iran
Authors: Delkhosh Marjan , Ardalan Ali , Foroushani Abbas Rahimi , Salehpoor-Emran Mohammad , Merghati-Khoei Effat 
Published: January 2024

Abstract
Background
Experiencing Intimate Partner Violence (IPV) by refugee women is debatable. Sexually Transmitted Infections (STIs) and Reproductive Tract Infections (RTIs) are IPV’s squeals. This study aimed to examine associations between IPV and RTI/STI.
Methods
This cross-sectional population-based household survey was conducted with 188 reproductive-age Afghan refugee women residing in a refugee settlement in a selected city in Iran, 2016-17. Data were collected using three self-report instruments: a Socio-demographic characteristics form, the Assessment of Intimate Partner Violence, Women’s self-reported RTI/STI-associated symptoms, and the Multi-country Study on Women’s Health and Domestic Violence against Women. The SPSS software (v. 22) was used to analyze the data at a significance level of less than 0.05. The chi-square test and Odds ratio (OR) with 95% confidence intervals (CI) were used. The logistic regression model evaluated associations between variables.
Results
The majority of women (79.8%) had ever experienced IPV during the last year and reported at least one symptom related to RTI/STI (70.2%). ‘Age 15–24 years’ (p = 0.037) (OR 0.49; 95% CI, 0.11–2.12), ‘no condom use’ (p = 0.014) (OR 5.31; 95% CI, 1.11–25.41) and ‘having forced anal sex’ (p = 0.036) (OR 0.49; 95% CI, 0.11–2.12) were found to be significantly associated with the reported symptoms. Most of the women (66.9%) neither sought help for their RTI/STI symptoms by healthcare nor received treatment. IPV was positively associated with RTI/STI -associated symptoms (p < 0.0001), having a history of RTI/STI diagnosis (p < 0.0001), and experiencing at least one of the most specific RTI/STI-associated symptoms (vaginal discharge and genital ulcers) (p < 0.0001). Women who had experienced any RTI/STI-associated symptoms experienced more sexual abuse from their spouses compared to women without any history of STI/RTI-reported symptoms (p < 0.0001) (OR 4.12; 95% CI, 1.87–9.08).
Conclusions
The prevalence of STI/RTI-associated symptoms among the Afghan refugee population is considerable. Also, the high prevalence of IPV and its strong links with the prevalence of reported RTI/STI-associated symptoms underline the urgent need for developing, testing, and implementing appropriate and timely interventions for managing RTI/STI and IPV simultaneously in refugee camps/settlements to tackle both violence and RTI/STI among refugee couples.
Positive effect of deactivated ion Tb3+ and non-optical active ion Al3+ co-doping on the Dy3+: CaLaGa3O7 crystal as a promising 574 nm yellow laser crystal
Authors: Liu Yunyun , Jiang Meimeng , Wang Lu , Huang Chuanxin , Gao Ju , Sun Yijian , Wang Yan 
Published: January 2024

Abstract

A deactivated ion Tb3+ and non-optical active ion Al3+ co-doped Dy3+: CaLaGa3O7 (abbr. as Dy/Tb: CLAGO) yellow laser crystal was successfully grown and studied. The band structure of CLAGO shows that the hybrid CLAGO matrix is suitable as luminescent materials. Before crystal grown, Dy/Tb: CLAGO polycrystals with different concentrations of Tb3+ were synthesized to select the optimal doping concentration of Tb3+ and the value is 0.2 at.%. Then, the Dy/Tb: CLAGO singly crystal was grown by Cz technology and the tetragonal structure was confirmed by XRD measurement. The effect of Tb3+ co-doping on the optical properties was investigated in detail. The excitation spectrum shows that the Dy/Tb: CLAGO can be effective pumped by a conventional 450 nm GaN LD. Under excitation at 450 nm, the emission spectrum not only contains the typical emissions of Dy3+, but also has a 543 nm emission band of Tb3+. In comparison to Dy: CLGO crystal, the Dy/Tb: CLAGO crystal possessed a larger emission cross-section (4.05×10-21 cm2) at the central wavelength of 574 nm. In addition, due to the introduction of Tb3+, the population on the laser lower level of Dy3+: 6H13/2 decreases, while the impact on the upper level (Dy3+: 4F9/2) is minimal. These results suggest that the Dy3+/Tb3+ co-doped CaLa(Al/Ga)3O7 crystal could be an attractive host for 574 nm yellow laser under a conventional 450 nm LD.