bluuebunny/crossref_metadata_2025_split huggingface dataset:
The ultrastructural identity of some cells in the nematode Sphaerolaimus gracilis.
Authors: Turpeenniemi T.A. 
Published: February 2024

Abstract
The fine structure of cells closely related to fibroblasts, lymphocytes, stem cells and steroidogenic cells in the nematode Sphaerolaimus gracilis was studied by transmission electron microscopy. The body regions of the renette pore (ventral pore) and coelomocytes were studied.
Fibroblasts, lymphocytes, and stem cells were found in the lateral position at the level of the renette pore. Fibroblastsare characterized by long and wide cellular processes. The cytoplasm consisted of a network of irregularly arranged microscopic tubules. The nucleus was very large, oval, or quadrangular. Occasionally, small, oval, or basket-shaped mitochondria and some fragments of rough endoplasmic reticulum were observed in the periphery of the cell. Lymphocytes had an extremely round cell body and a very large round nucleus encircled by a thin cytoplasmic rim. Several pieces of rough endoplasmic reticulum, an oval mitochondrion, and several ribosomes were observed in the cytoplasm. A large rectangular stem cell abutted lymphocytes dorsally on both sides of the esophagus. In the cytoplasm of stem cells, there were tiny filaments in the rough endoplasmic reticulum, a centrosome, and small vesicles in the periphery of the cell. The nucleolus was characterized by a granular structure. Steroidogenic cellswere embedded into the lateral epidermal cord of the coelomocyte region in the corner of two lateral epidermal cells. The cell body was characterized by a large nucleus, a voluminous vacuole, tubular mitochondria, vesicular bodies, and rough endoplasmic reticulum. Two longitudinally traveling and morphologically different lateral nerves were close to the steroidogenic cells, and both ran in the corner of the neighboring lateral epidermal cells with a connection to the coelomic space.
mCodeGPT: Bridging the Gap between Unstructured Medical Text and Structured Cancer Ontologies
Authors: Zhang Kai , Huang Tongtong , Malin Bradley A , Osterman Travis , Long Qi , Jiang Xiaoqian 
Published: February 2024

Abstract
The rapidly growing collection of clinical free text data about cancer provides an unprecedented opportunity to harness rich, real-world insights for advancing cancer research and treatment. At the same time, there is a formidable challenge in efficiently extracting, standardizing, and structuring this vast and unstructured information to derive meaningful conclusions. In this paper, we address the problem of information extraction to standardize and structure such free text using large language models (LLMs) following the minimal Common Oncology Data Elements (mCODE™) structure. To this end, we implement mCodeGPT, an approach that ingests the cancer ontology knowledgebase and hierarchically generates prompts to extract relevant information from clinical notes. The generated output is subsequently organized and displayed in a tabular and structured format for improved analysis and interpretation. Our approach is annotation-free and eliminates the need for model training. mCodeGPT achieved over 95% accuracy for named entity recognition on mCODE concepts,
Greywater Reuse
Authors: Gross Amit , Maimon Adi , Alfiya Yuval , Friedler Eran 
Published: February 2024

Abstract
Greywater Reuse examines the features and implications of greywater reuse scientifically, quantitatively, and thoroughly. Based on the authors' extensive studies of treatment facilities in urban and rural environments, development of greywater treatment systems, and research of potential environmental and health risks posed by greywater at different treatment levels, this authoritative text: Describes the chemical, physical, and microbial properties of greywater Covers the treatment and removal of greywater pollutants, providing case studies of common methodsIdentifies the risks involved in greywater use and proposes regulatory measures to help reduce these risksReviews the greywater management strategies, policies, and legislation of several different countriesDiscusses the prevailing public perception and willingness to adopt various uses of greywaterAnalyzes the economic impact of greywater reuse from both the consumer and national perspectives
This title is co-published with CRC Press Amit Gross, Jacob Blaustein Institutes for Desert Research, Israel, Adi Maimon, Ben-Gurion University of the Negev, Israel, Yuval Alfiya, Technion–Israel Institute of Technology, Haifa, Israel and Eran Friedler, Technion–Israel Institute of Technology, Haifa, Israel.
Rethinking community-led total sanitation for eradicating open defecation in rural Ebonyi state communities, Nigeria: practice considerations for social work practitioners and educators
Authors: Agha Agha Ali , Osuu Christopher , Onalu Chinyere Edith , Adewoyin Yemi 
Published: February 2024

Abstract
Nigeria is ranked number two in the world with the highest prevalence of open defecation (OD) despite the adoption of community-led total sanitation (CLTS) since 2007. Using some CLTS-triggered communities in Ebonyi State, this study investigated the awareness of CLTS, OD status, and its drivers as well as social workers' involvement in environmental sustainability. Study data generated from primary surveys included the socio-demographic characteristics of the study population and measurable behavioral elements of the SaniFOAM framework. Results of the statistical analyses show that more than 79% of the respondents were aware of CLTS, yet OD prevalence was 84.8%. While being married (odds ratio (OR): 0.036), being a civil servant (OR: 0.109), and having at least secondary education (OR: 0.119) were associated with lower odds of OD, whereas dislike for trekking (OR: 4.322), absence of laws (OR: 5.380), sanctions (OR: 4.715), and other SaniFOAM variables were associated with increased odds of OD. The results suggest that behavioral change toward OD under CLTS, with its focus on community mobilization for self-awareness and self-assessment for eliminating OD, may be a mirage without stricter approaches, laws, and sanctions for behavioral change. The domiciliation of these within grassroot governments and social workers' involvement in sanitation promotion are suggested.
Can Blue-Green Infrastructure enhance resilience in urban drainage systems during failure conditions?
Authors: Mugume Seith N. , Kibibi Hilary , Sorensen Johanna , Butler David 
Published: February 2024

Abstract

The need to enhance the resilience of urban drainage systems (UDSs) in view of emerging global climate change and urbanisation threats is well recognised. Blue-Green Infrastructure (BGI) provides a suitable strategy for building the resilience of existing UDSs. However, there are limited quantitative studies that provide evidence of their effectiveness for increased uptake in cities. In this research, coupled one-dimensional–two-dimensional (1D–2D) modelling is applied to assess the effectiveness of BGI that include rainwater harvesting systems, infiltration trenches, bioretention cells, and detention ponds using two case study UDSs located in Kampala that experience catastrophic pluvial flooding caused by extreme rainfall. The resulting flooding impacts are quantified considering ‘failed’ and ‘non-failed’ UDS initial states, using total flood volume and average flood duration as system performance indicators. The study results suggest that spatially distributed rainwater harvesting systems singularly lead to a reduction in total flood volume and average flood duration of 16–45% and 18–24% in the case study UDSs, respectively. Furthermore, the study results suggest that BGIs are more effective during moderate rainfall (T &lt; 10 years). Based on the study findings, city scale implementation of multifunctional rainwater harvesting systems is recommended as a suitable strategy for enhancing UDSs’ resilience.
BRASIL ACIMA DE TUDO, DEUS ACIMA DA VIDA
Authors: Souza Marco Aurélio Dias de 
Published: February 2024

Os últimos meses no Brasil, além de serem marcados pelo medo trazido pela enorme quantidade de óbitos relacionados a COVID-19, também foram palco de um espetáculo de desinformação, irresponsabilidades e desdém com a vida. Se não bastasse a minimização dos riscos da doença por parte do presidente da república, ainda se viu a incitação às manifestações, campanhas de seus aliados para que apoiadores rompessem a quarentena nos estados que a aderiram e tentativas da utilização de brechas na lei para flexibilizá-la. Nesse sentido, o artigo tem como tema o debate a respeito da disputa para se colocar as atividades religiosas como atividades essenciais durante a pandemia, ao entender esse movimento como uma resposta direta das relações entre Bolsonaro e setores religiosos conservadores/reacionários, que garantiram sua eleição, e estabelecendo que dentro de um governo que propõe uma narrativa de que a economia não pode parar, a definição da fé como um grande negócio parece bastante adequada para o cenário atual.
Potential Role of Bone Metabolism Markers in Kidney Transplant
Recipients
Authors: Vigil Flávia Maria Borges , Castro Pedro Alves Soares Vaz de , Hasparyk Ursula Gramiscelli , Bartolomei Victória Soares , Silva Ana Cristina Simões e 
Published: February 2024

Background:
The impact of treatments, suppressing the immune system, persistent
hyperparathyroidism, and other risk factors on mineral and bone disorder (MBD)
after kidney transplantation is well-known. However, there is limited knowledge about
their effect on bone metabolism biomarkers. This study aimed to investigate the influence
of kidney transplant on these markers, comparing them to patients undergoing hemodialysis
and healthy individuals.

Methods:
In this cross-sectional study, three groups were included: kidney transplant patients
(n = 57), hemodialysis patients (n = 26), and healthy controls (n = 31). Plasma concentrations
of various bone metabolism biomarkers, including Dickkopf-related protein
1, osteoprotegerin, osteocalcin, osteopontin, sclerostin, and fibroblast growth factor 23,
were measured. Associations between these biomarkers and clinical and laboratory data
were evaluated.

Results:
A total of 114 patients participated. Transplant recipients had significantly lower
levels of Dickkopf-related protein 1, osteoprotegerin, osteocalcin, osteopontin, sclerostin,
and fibroblast growth factor 23 compared to hemodialysis patients. Alkaline phosphatase
levels positively correlated with osteopontin (r = 0.572, p < 0.001), while fibroblast
growth factor 23 negatively correlated with 25-hydroxyvitamin D (r = -0.531, p
= 0.019). The panel of bone biomarkers successfully predicted hypercalcemia (area under
the curve [AUC] = 0.852, 95% confidence interval [CI] = 0.679-1.000) and dyslipidemia
(AUC = 0.811, 95% CI 0.640-0.982) in transplant recipients.

Conclusion:
Kidney transplantation significantly improves mineral and bone disorders
associated with end-stage kidney disease by modulating MBD markers and reducing
bone metabolism markers, such as Dickkopf-related protein 1, osteoprotegerin, osteocalcin,
osteopontin, and sclerostin. Moreover, the panel of bone biomarkers effectively
predicted hypercalcemia and dyslipidemia in transplant recipients.
Study on the Expression and Potential Function of LncRNA in Peripheral
Blood of Patients with Ankylosing Spondylitis
Authors: Hong-Yuan Xie , Yi-Ping Tang , Ting Yi , Xia Liao , Quan-Bo Zhang , Yu-Feng Qing , Fei Dai 
Published: February 2024

Background:
Ankylosing spondylitis (AS) is an autoimmune disease that has the characteristics
of difficult early diagnosis and a high disability rate.

Objective:
The objective of this study was to further explore the possible mechanism and potential
function of lncRNA in AS.

Methods:
We used lncRNA microarray technology to detect the expression of lncRNA and mRNA
in patients with active AS, stable patients, and healthy controls (HC). Afterward, bioinformatics
analysis was conducted on differentially expressed genes. Seven differentially expressed lncRNAs
were screened out for real-time fluorescent quantitative PCR (RT-qPCR), combined with
various clinical indicators for correlation analysis, and the receiver operating characteristic (ROC)
curve was used to analyze the potential of lncRNA as a diagnostic marker for AS.

Results:
The results showed that the expression levels of NR-037662 and ENST00000599316 in
the AS subgroups were significantly higher than those in the HC group, while the expression levels
of ENST00000577914 and ENST00000579003 were lower than those in the HC group. The expression
levels of NR-003542 and ENST00000512051 in the ASA group were significantly higher
than those in the ASS and HC groups, while NR-026756 was just the opposite. Spearman’s correlation
analysis showed that the expression level of NR-003542 was positively correlated with
Bath Ankylosing Spondylitis Functional Index (BASFI), Erythrocyte Sedimentation Rate (ESR),
and high sensitivity C-Reactive Protein (hsCRP). The expression level of NR-026756 was negatively
correlated with the Bath Ankylosing Spine Inflammatory Disease Activity Index (BASDAI),
BASFI, ESR, hsCRP, and globulin (GLOB). In addition, it was also found that the ROC
curve analysis of the 4 lncRNAs between the AS group (ASA group and ASS group) and the HC
group were statistically significant, and the area under the curve (AUC) of NR-037662, ENST00000599316,
ENST00000577914, and ENST00000579003 was 0.804, 0.812, 0.706, and
0.698, respectively.

Conclusion:
It was found that these differentially expressed lncRNAs of AS may be involved in
the occurrence and development of the disease. Among them, NR-037662, ENST00000599316,
ENST00000577914, and ENST00000579003 might have the potential to become AS diagnostic
molecular markers. Moreover, NR -003542, ENST00000512051, and NR-026756 might have the
potential to be indicators of disease activity.
Antiphytopathogenic Diphenyl Ethers from the Marine-derived Fungus
Aspergillus sydowii
Authors: Shi Ying , Yang Xiao , Ren Jinwei , Liu Ling 
Published: February 2024

Background:
Natural products from the marine-derived Aspergillus sp. have great potential
in agricultural usage due to their broad biological activities.

Objective:
This study was designed to investigate the antiphytopathogenic compounds from marinederived
fungus Aspergillus sydowii LW09.

Methods:
The compounds were isolated and purified by chromatography methods, and their structures
were elucidated by analysis of the NMR and MS spectroscopic data as well as comparison with
those of literature. All compounds were evaluated for antibacterial activities against phytopathogenic
bacteria Pseudomonas syringae and Ralstonia solanacarum, along with spore germination inhibition
of phytopathogenic fungi Fusarium oxysporum and Alternaria alternata.

Results:
Two diphenyl ethers violaceols I (1) and II (2), along with two alkaloids acremolin (3) and
WIN 64821 (4) were isolated from the fermentation extracts of A. sydowii LW09. Compound 1
showed significant antibacterial activity against P. syringae and R. solanacarum with the same MIC
values of 4 μg/mL, while compound 2 showed obvious antibacterial activity against P. syringae and
R. solanacarum with MIC values of 2 and 1 μg/mL, respectively. Moreover, both 1 and 2 could inhibit
the spore germination of F. oxysporum in the concentration range of 64–128 μg/mL. In addition,
violaceol I (1) also inhibited the spore germination of A. alternata at 128 μg/mL.

Conclusion:
This study provided the potential antiphytopathogenic drug candidate for further studies.
Aplicación móvil para la comercialización de arepa de huevo de las productoras del municipio de Luruaco
Authors: Avila Pérez Mario Luis , Avila Muñoz Carlo Mario , Vargas Pertuz Elvira María , Avila García Bibiana del Carmen , Reid García Yarli Cecilia 
Published: February 2024

The project consists of developing a mobile application for Arepa de Huevo producers in the municipality of Luruaco, using the agile XP development methodology. An analysis of requirements and a literature review are conducted to meet the need for access to new marketing channels. The application development was divided into four phases: exploration, design, development, testing and deployment. We used "Thinking Aloud" methodology was used in usability testing, where users spoke about their thoughts while interacting with the application. The test results showed good ratings in aesthetics, ease of use, content and information, and usefulness of the application. User feedback was collected for future improvements. The development of the application has been a significant experience for the authors, facing the challenge of learning a new programming language and using tools like Nodejs and React Native. Additionally, the satisfaction of contributing to the community and applying acquired knowledge to solve local problems is highlighted. The result of this exercise is a mobile application that meets the requirements and needs of egg arepa producers in Luruaco, applying the XP methodology and obtaining satisfactory results.
El diseño de alimentos como proceso de innovación
Authors: Pérez Cardona Carmen Adriana , Romero Cuéllar Javier Augusto 
Published: February 2024

Gastronomy is a practice inherent to human culture, it is the result of preparing dishes taking care of the presentation, seasoning and creation of new ways of mixing, generating food security, as well as the reception within society in the desire to experience new sensations. gustatory, olfactory, or kinesthetic.

This allows us to know the cultural traits of the different communities. It is there where food design has had a great boom and where our broad culture can generate important economic developments for the regions.

Within the academic process addressed from the Industrial Design program, this topic has been addressed from different courses, allowing to achieve important developments in the presentation, experience, and design of food, articulating cultural, artistic, architectural values that additionally expand the tourist offer of the regions. being the recognition of ancestral knowledge part of the cultural heritage of our diversity, which has achieved a multiplicity of innovative results which we systematize for this presentation. Innovation is approached from the generation of new ideas regarding the presentation of food, the creation of processes to facilitate the production of products, the design of the experience as a primary factor in market segmentation and the creation of new mixtures to from experimentation.
Measuring Accountable Information in CSR Reports: A New Operationalization and Analysis Applied to Greenhouse Gas Disclosures
Authors: Huq Asif M. , Carling Kenneth 
Published: February 2024

ABSTRACT
We develop a novel and generic text-based measure to classify and evaluate greenhouse gas (GHG) disclosures. We construct the measure using collocation analysis of GHG-related words and regular expressions. Automated implementation achieved high concordance compared to manual investigations. We move beyond the “bag-of-words” approach in classifying voluminous nonfinancial corporate disclosure. We also outline a methodology that is manyfold scalable and makes replicability straightforward. Compared to past studies, we work with a significantly larger sample of 5,017 reports across 80 countries, thereby dealing with greater complexity and leading to better generalizability. We also contribute to the debate on whether nonfinancial disclosures exhibit accountability or are merely greenwashing. We find a negative trend in accountability worldwide, and firm-level accountability in GHG disclosures is not detectable in a country-level reduction of GHG emissions. Moreover, firms disclose significantly higher accountable information in a civil-law legal environment compared to those in a common-law legal environment.
JEL Classifications: M14; M40.
Peran Persepsi Dukungan Sosial sebagai Mediator antara Trait Mindfulness dan Motivasi Akademik Mahasiswa
Authors: Rahmadini Rizqika , Salim Rose Mini Agoes 
Published: February 2024

Selama pembelajaran jarak jauh, mahasiswa banyak yang merasa kesulitan mempertahankan motivasi akademik. Studi terdahulu menemukan trait mindfulness dapat meningkatkan motivasi akademik, namun hubungan kedua variabel tersebut masih inkonsisten. Penelitian ini bertujuan untuk menganalisis peran persepsi dukungan sosial sebagai mediator antara trait mindfulness dan motivasi akademik pada mahasiswa yang menjalani perkuliahan jarak jauh. Tipe penelitian adalah kuantitatif non-eksperimental dengan desain cross-sectional study. Data dikumpulkan menggunakan tiga alat ukur yang telah diadaptasi yaitu Academic Motivation Scale (AMS), Mindful Attention Awareness Scale (MAAS), dan Multidimensional Scale of Perceived Social Support (MSPSS). Terdapat total 162 mahasiswa jenjang sarjana dan pascasarjana yang menjadi partisipan. Analisis data dilakukan menggunakan mediasi model 4. Hasil penelitian menunjukkan ketiga variabel berhubungan positif dan linear, serta persepsi dukungan sosial memediasi hubungan trait mindfulness dan motivasi akademik secara penuh. Dengan demikian, semakin tinggi trait mindfulness yang dimiliki mahasiswa akan membantu mereka melihat situasi pembelajaran secara lebih positif dan menerima dukungan sosial, dan mahasiswa dapat meningkatkan pula motivasi akademik. Implikasi dari temuan ini bagi mahasiswa bisa mencoba mengembangkan praktik mindfulness dalam kehidupan kesehariannya maupun mengikuti pelatihan berbasis meditasi.
LA LOGÍSTICA INVERSA Y SU IMPORTANCIA EN LA FUERZA TERRESTRE DEL ECUADOR
Authors: Mora Rafael , Rodríguez Jorge Jimmy 
Published: February 2024

El propósito del presente artículo es exponer una investigación exhaustiva que permita sentar las bases para develar la importancia de la logística inversa en el ámbito militar, concretamente en la Fuerza Terrestre, y determinar su situación en los procesos actualmente desarrollados por la institución. Para esto, se aplicó un estudio no experimental, descriptivo y cualitativo, apoyado en una indagación bibliográfica y de campo, así como en estrategias que permiten presentar los hallazgos de una forma ordenada y sistemática.
Así se evidencia el gran valor de los procesos de retorno o de logística inversa en los ámbitos institucional y medioambiental, además de su influencia en la imagen, la economía y la responsabilidad de la Fuerza Terrestre. Todo esto se sintetiza en las conclusiones, que indican concretamente que en el Ecuador la logística militar inversa se encuentra en desarrollo y aunque se ha implementado en algunos niveles logísticos y en pocos procesos, es mucho el trabajo que le queda por realizar a la institución militar para su integral implantación. Se recomienda hacerlo a la brevedad posible para acogerse a los beneficios que esta proporciona, entre los que se destacan la reducción del consumo de recursos y la minimización de los costes, además de la gestión responsable desde el punto de vista del medioambiente.
Nuevos enfoques de la aeronavegabilidad militar en el Ecuador
Authors: Narváez Roberto 
Published: February 2024

El estudio expuso nuevos enfoques en el tratamiento de la aeronavegabilidad militar en el Ecuador, tomando como base la accidentabilidad en el periodo 2007-2022, y estableciendo un diagnóstico que determinó que cada fuerza se norma y regula en el ámbito técnico aeronáutico de manera independiente. Se propuso una estandarización y unificación de procesos a través de la creación de un organismo con el rol de autoridad aeronáutica militar, que sea responsable final de la aeronavegabilidad en todas las aeronaves militares con las particularidades propias de este tipo de aviación y con una proyección al ámbito estatal, esto se logró estableciendo un método Delphi el cual permitió un análisis prospectivo sistemático de la problemática planteada, analizando aspectos como criterios de normalización y regulación, eficiencia, organizacionales, además de desarrollo de la industria aeronáutica junto con procesos I+D+i, determinándose la necesidad de la implementación de un nuevo enfoque militar conjunto de la aeronavegabilidad lo que permitirá mejorar la seguridad, eficiencia y eficacia en las operaciones aéreas militares en el Ecuador.