bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improved dual‐mode double‐ring resonator with radial stub for UWB‐filter design
Authors: Liu Ji‐Chyun , Wu Ching‐Yang , Chiang Ming‐Hsun , Soong David 
Published: December 2004

AbstractAn improved filter design of a dual‐mode double‐ring resonator with radial stub for ultra‐wideband (UWB) applications is presented in this paper. Based on the double‐ring resonator and adjusted voltage/current couplings, two radial stubs are added to the outer ring in order to construct the band‐pass filter. The dual‐mode double‐ring resonator exhibits wideband responses, and the radial stubs enhance the bandwidth of the operating‐frequency band. Thus, an alternative approach to improve the bandwidth of the conventional dual‐mode double‐ring resonator, is presented. The experimental and simulation results are given and discussed. © 2005 Wiley Periodicals, Inc. Microwave Opt Technol Lett 44: 219–222, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.20593
A compact higher‐order ADI‐FDTD method
Authors: Fu Weiming , Tan Eng Leong 
Published: December 2004

AbstractA 2D higher‐order alternating‐direction‐implicit (ADI) finite‐difference time‐domain method based on a compact scheme is presented in this paper. This compact ADI method improves the efficiency of computation by reducing the bandwidth of the matrix to be inversed from seven to five for the 4th‐order scheme. The method is proved to be unconditionally stable and its dispersion analysis is also presented. © 2005 Wiley Periodicals, Inc. Microwave Opt Technol Lett 44: 273–275, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.20609
A combination of FDTD and least‐squares support vector machines for analysis of microwave integrated circuits
Authors: Yang Y. , Hu S. M. , Chen R. S. 
Published: December 2004

AbstractThis paper presents a new combination of the finite‐difference time‐domain (FDTD) method and the least‐squares support vector machines (LS‐SVM) technique. The LS‐SVM is a statistical‐learning method which has a self‐contained basis of statistical‐learning theory and excellent learning performance. A short segment of an FDTD record is used to train the LS‐SVM predictor in order to obtain an accurate future realization. Numerical simulations for two typical microwave filters demonstrate that the LS‐SVM method can achieve good forecasting accuracy and the efficiency of the FDTD method can be improved by up to 70%. © 2005 Wiley Periodicals, Inc. Microwave Opt Technol Lett 44: 296–299, 2005; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/mop.20615
Significant responses to platinum‐based chemotherapy in renal medullary carcinoma
Authors: Strouse John J. , Spevak Melissa , Mack A. Kyle , Arceci Robert J. , Small Donald , Loeb David M. 
Published: December 2004

AbstractMost patients with renal medullary carcinoma (RMC) have advanced disease at presentation and rarely respond to radiation or chemotherapy. We describe two adolescents with metastatic disease who had significant responses to cisplatin or carboplatin in combination with gemcitabine and paclitaxel. © 2004 Wiley‐Liss, Inc.
Influence of wave modelling on the prediction of fatigue for offshore wind turbines
Authors: Veldkamp H. F. , van der Tempel J. 
Published: December 2004

AbstractCurrently it is standard practice to use Airy linear wave theory combined with Morison's formula for the calculation of fatigue loads for offshore wind turbines. However, offshore wind turbines are typically placed in relatively shallow water depths of 5–25 m where linear wave theory has limited accuracy and where ideally waves generated with the Navier–Stokes approach should be used. This article examines the differences in fatigue for some representative offshore wind turbines that are found if first‐order, second‐order and fully non‐linear waves are used. The offshore wind turbines near Blyth are located in an area where non‐linear wave effects are common. Measurements of these waves from the OWTES project are used to compare the different wave models with the real world in spectral form. Some attention is paid to whether the shape of a higher‐order wave height spectrum (modified JONSWAP) corresponds to reality for other places in the North Sea, and which values for the drag and inertia coefficients should be used. Copyright © 2004 John Wiley & Sons, Ltd.
Forecasting offshore wind speeds above the North Sea
Authors: Tambke Jens , Lange Matthias , Focken Ulrich , Wolff Jörg‐Olaf , Bye John A. T. 
Published: December 2004

AbstractWe investigate the expected performance of short‐term wind power prediction systems for offshore sites in the German Bight and at Horns Rev. Despite the special meteorological situation over the North Sea, it is found that the accuracy of wind speed predictions provided by the numerical prediction model of the German weather service is comparable to that of onshore predictions. However, although relative forecast errors look promising, the absolute errors are fairly large, with a root mean square error up to 3 m s−1 for the 48 h forecast. Moreover, vertical wind profiles which are typically needed to calculate the wind speed at hub height are considered at Horns Rev. In all thermal conditions the measured profiles show significant deviations from the expected shapes. The reason for this has to be clarified. Assuming that the deviations are due to the physical processes in the marine boundary layer, we present an alternative approach to derive wind profiles over the ocean which involves the inertial coupling of the Ekman layers of atmosphere and sea via a wave boundary layer with constant shear stress. Profiles calculated by this method are compared with measured profiles, showing rather good agreement. Copyright © 2004 John Wiley & Sons, Ltd.
Ethnic identity, self‐esteem, and perceived efficacy as mediators of the relation of supportive parenting to psychosocial outcomes among urban adolescents☆
Authors: Swenson Rebecca R. , Prelow Hazel M. 
Published: December 2004

AbstractThe present study examined the direct and indirect relationships among supportive parenting, ethnic identity, self‐esteem, perceived efficacy, and psychological adjustment in an urban sample of 133 African American (M age=16.37) and 110 European American (M age=16.43) adolescents. Although the mediational model was partially supported for both African American and European American youth, the data better fit the model for the African American group. Specifically, perceived efficacy fully mediated the relation between ethnic identity and depressive symptoms, and partially mediated the relation between self‐esteem and depressive symptoms for African American youth. For European Americans, self‐esteem fully mediated the relation between supportive parenting and perceived efficacy. This study illustrates the importance of examining developmental models separately for adolescents from different ethnic/racial backgrounds.
Stabilization of macromolecular chromatin complexes in mitotic chromosomes by light irradiation in the presence of ethidium bromide
Authors: Sheval Eugene V. , Kireev Igor I. , Polyakov Vladimir Yu. 
Published: December 2004

AbstractA method was developed for stabilizing mitotic chromosomes. Light irradiation of permeabilized cells in a low concentration of ethidium bromide made chromatin resistant to high salt concentrations and decondensing buffer. This resistance was abolished by proteinase treatment, but not by DNase or RNase treatment. In photostabilized and extracted chromosomes, chromatin appeared as thick fibers with discrete high electron density regions. These stabilized structures might correspond to the higher‐level structures (chromonemata) observed in native chromatin. Moreover, the electron density was higher in the centromeric regions than the chromosome arm material. Thus, the method allows chromatin substructures (chromonemata and centromeric heterochromatin) to be stabilized inside mitotic chromosomes.
Phosphorylation of actin‐binding protein (ABP‐280; filamin) by tyrosine kinase p56lck modulates actin filament cross‐linking
Authors: Sharma C. Pal , Goldmann Wolfgang H. 
Published: December 2004

AbstractActin‐binding protein (ABP‐280; filamin) is a phosphoprotein present in the periphery of the cytoplasm where it can cross‐link actin filaments, associate with lipid membranes, and bind to membrane surface receptors. Given its function and localization in the cell, we decided to investigate the possibility of whether it serves as substrate for p56lck, a lymphocyte‐specific member of the src family of protein tyrosine kinases associated with cell surface glycoproteins. The interaction of p56lck with membrane glycoproteins is important for cell development and functional activation. Here, we show that purified p56lck interacts and catalyzes in vitro kinase reactions. Tyrosine phosphorylation by p56lck is restricted to a single peptide of labeled ABP‐280 shown by protease digest. The addition of phorbol ester to cells results in the inhibition of phosphorylation of ABP‐280 by p56lck. These results show a decrease in phosphorylation suggesting conformationally induced regulation. Dynamic light scattering confirmed increased actin filament cross‐linking due to phosphorylation of ABP‐280 by p56lck.
Synapsin IIb interacts with the C‐terminal SH2 and SH3 domains of PLCγ1 and inhibits its enzymatic activity
Authors: Han Seung Jin , Hong Seung Hwan , Kim Chul Geun , Lee Jung Bin , Choi Dong Kug , Kim Kyong‐Rae , Kim Chan Gil 
Published: December 2004

AbstractTo elucidate the function of PLCγ1, we have investigated the proteins that bind to its SH (Src homology) domain. Immunoscreening was performed with purified antisera specific for SH223 (two SH2 and one SH3)‐binding proteins. Several immunoreactive clones were identified as putative binding proteins and one of them was identified as synapsin IIb. We demonstrate a stable association between PLCγ1 and synapsin IIb, which binds the carboxyl terminal SH2 and SH3 domains of the enzyme and inhibits it.
Relation of myocardial histomorphometric features and left ventricular contractile reserve assessed by high‐dose dobutamine stress echocardiography in patients with idiopathic dilated cardiomyopathy
Authors: Otašević Petar , Popović Zoran B. , Vasiljević Jovan D. , Vidaković Radislav , Pratali Lorenza , Vlahović Alja , Nesšković Aleksandar N. 
Published: December 2004

AbstractBackgroundThis study was designed to determine the relationship between histomorphometric features and contractile reserve assessed by high‐dose dobutamine stress echocardiography in patients with idiopathic dilated cardiomyopathy.MethodsTwenty‐four consecutive patients (21 men, aged 43.4±8.7 years) with idiopathic dilated cardiomyopathy underwent dobutamine stress echocardiography. Wall motion score index, ejection fraction, cardiac power output and end‐systolic pressure/volume ratio were used as indices of left ventricular contractility. Left ventricular endomyocardial biopsy specimens (3–5 per patient) were routinely processed and stained with Masson trichrome, interstitial fibrosis and myocyte diameter were calculated quantitatively.ResultsMyocyte diameter and interstitial fibrosis showed strongest correlation with change in wall motion score index (r=−0.667, p<0.001, and r=−0.567, p=0.004, respectively), followed by change in ejection fraction (r=−0.603, p=0.002, and r=−0.467, p=0.021, respectively). Interstitial fibrosis showed no correlation with change of cardiac power output and end‐systolic pressure/volume ratio, whereas myocyte diameter was associated with change of both indices (r=−0.565, p=0.004, and r=−0.455, p=0.025).ConclusionsContractile reserve elicited by high‐dose dobutamine is strongly related to the degree of histological disruption in patients with idiopathic dilated cardiomyopathy.
Reduced myocardial velocities of left ventricular long‐axis contraction identify both systolic and diastolic heart failure—a comparison with brain natriuretic peptide
Authors: Vinereanu Dragos , Lim Pitt O. , Frenneaux Michael P. , Fraser Alan G. 
Published: December 2004

BackgroundEchocardiographic diagnosis of radial fractional shortening or global ejection fraction fails to diagnose all patients with heart failure; about 40%, with apparently normal global systolic function, will have elevated brain natriuretic peptide (BNP) concentrations and “pure” diastolic dysfunction. Screening methods do not include assessment of left ventricular (LV) longitudinal function, however, which is a more sensitive marker of subclinical disease.AimsWe investigated the diagnostic potential of assessment of LV longitudinal function in suspected heart failure, in a comparison against BNP.MethodsFifty consecutive subjects (aged 65±12 years; 30 men) referred to a heart failure clinic with unexplained breathlessness were examined by echocardiography and had plasma BNP measured by fluorescence immunoassay.ResultsGlobal systolic function (ejection fraction) correlated moderately with log‐transformed BNP (r=−0.54), as did global diastolic function (r=0.55 for estimated LV filling pressure, and r=−0.51 for transmitral flow propagation velocity), and radial systolic function (r=−0.60) (all p<0.001). The echocardiographic parameter that correlated best with BNP, however, was LV longitudinal systolic function (r=−0.78, p<0.001). By stepwise multiple regression analysis, BNP was predicted by longitudinal systolic velocity, in association with LV mass index and radial systolic velocity (r=0.81, r2=0.66, p<0.0001). The sensitivity and specificity of a longitudinal systolic velocity of ≤5.5 cm/s (mean of 4 basal segments) to diagnose heart failure (defined as an elevated BNP) were 94% and 85%, respectively; the negative predictive value was 97%.ConclusionNon‐invasive diagnosis or exclusion of suspected heart failure, whether systolic or diastolic, can be performed accurately by echocardiographic measurement of LV longitudinal systolic function.
Rapid progression from hypertrophic cardiomyopathy to heart failure in a patient with Becker's muscular dystrophy
Authors: Park Ok Young , Ahn Youngkeun , Park Woo Seok , Lim Ji Hyun , Park Hyung Wook , Kim Ju Han , Hong Young Joon , Kim Weon , Jeong Myung Ho , Cho Jeong Gwan , Park Jong Chun , Lee Min Cheol , Kang Jung Chaee 
Published: December 2004

AbstractWe describe the case of a 17‐year‐old boy with Becker*s muscular dystrophy (BMD) presenting with rapid progression from hypertrophic cardiomyopathy to heart failure within 2 years. Initial echocardiogram showed severe hypertrophy of left ventricle (LV) and right ventricle (RV) with normal chamber size, and preserved LV systolic function. Microscopic study of cardiac muscle obtained by endomyocardial biopsy of the interventricular septum showed severe hypertrophy of the muscle fibers and interstitial fibrosis. Follow‐up echocardiogram 2 years after the first examination exhibited marked dilated LV and RV with severe LV global hypokinesia. Follow‐up endomyocardial biopsy demonstrated increased interstitial cellular matrix. Immunohistochemical staining for dystrophin revealed significant loss of dystrophin along the sarcoplasmic membrane of the right biceps brachii muscle, compatible with BMD.
Clinical trials update from the American Heart Association meeting: ACORN‐CSD, primary care trial of chronic disease management, PEACE, CREATE, SHIELD, A‐HeFT, GEMINI, vitamin E meta‐analysis, ESCAPE, CARP, and SCD‐HeFT cost‐effectiveness study
Authors: Shelton Rhidian J. , Velavan Periaswamy , Nikitin Nikolay P. , Coletta Alison P. , Clark Andrew L. , Rigby Alan S. , Freemantle Nick , Cleland John G.F. 
Published: December 2004

AbstractThis article provides information and a commentary on landmark trials presented at the American Heart Association meeting held in November 2004, relevant to the pathophysiology, prevention, and treatment of heart failure. An open trial of the ACORN Cardiac Support Device (CSD) showed encouraging preliminary results in patients with severe heart failure. The PEACE (Prevention of Events with Angiotensin‐Converting Enzyme inhibition) study supports data from previous studies showing that ACE inhibitors reduce vascular events in patients at increased risk. The CREATE (clinical trial of metabolic modulation in acute MI treatment evaluation) study of patients with acute myocardial infarction (MI) showed no mortality benefit of a glucose/insulin/potassium regimen, but treatment with reviparin reduced the incidence of death, MI, or stroke. Azimilide was not associated with a significant reduction in shocks, but reduced the shocks or episodes of markedly symptomatic ventricular tachycardia terminated by pacing in the SHIELD (Shock Inhibition Evaluation with Azimilide) study. The addition of isosorbide dinitrate plus hydralazine to standard therapy improved survival in black heart failure patients in the A‐HeFT (African—American Heart Failure Trial) study. In an investigation of hypertensive patients with diabetes, carvedilol had fewer adverse effects on diabetic control than metoprolol. A meta‐analysis of high‐dose vitamin E supplementation suggested an association with increased mortality. The ESCAPE (Evaluation Study of CHF and Pulmonary Artery Catheterisation Effectiveness) study showed no benefit of pulmonary artery catheterisation over clinical management in patients with severe heart failure. Routine prophylactic coronary revascularisation for stable coronary disease prior to major vascular surgery showed no benefit in the CARP (Coronary Artery Revascularization Prophylaxis) study. Analysis of data from SCD‐HeFT supports the cost‐effectiveness of ICDs in heart failure, although overall cost implications may be prohibitive.
Bonamia exitiosa epizootic in Ostrea chilensis from Foveaux Strait, southern New Zealand between 1986 and 1992
Authors: Cranfield H.J. , Dunn A. , Doonan I.J. , Michael K.P. 
Published: December 2004

Abstract
Disease caused by the haplosporidian parasite, Bonamia exitiosa, swept through the dredge oyster (Ostrea chilensis) population of Foveaux Strait between 1986 and 1992, with consequent mortality reducing the population to 9% of the pre-disease level. Dead and dying oysters were first seen by fishers in far western Foveaux Strait in 1985 and more were found further east in 1986. Infection spread slowly through Foveaux Strait so the progress of the epizootic can be described from population surveys. A wave of infection radiated through the oyster population from the epicentre of infection in central western Foveaux Strait, and was followed by a wave of mortality. The epizootic ceased in oyster beds around the margins of oyster distribution in 1992. Infective particles released by diseased oysters spread through the water to infect other oysters directly. The epizootic broadly fitted a simple deterministic epizootic model and suggested that both diffusion and turbulent processes were important in transmission of infection. Bonamia exitiosa was also present in oysters at the end of an epizootic in 1964 and was probably the cause of that epizootic. Bonamiasis appears to be an endemic disease in Foveaux Strait. The high mortality in the 1986–1992 epizootic was like that caused by a newly introduced disease in an immunologically naïve population. We propose that other stressors have increased the susceptibility of oysters to this disease. Mechanical disturbance of oysters by increasingly intense dredging appears to be a major source of stress, as does the increasing scale of modification of benthic habitat by fishing. Recovery of the oyster population after the epizootic is closely linked to regeneration of habitat. The prognosis for the fishery could be improved by mitigating mechanical disturbance during dredging by use of lighter dredges and less damaging towing strategies, as well as pursuing rotational fishing strategies that allow benthic habitat to regenerate in undisturbed areas.
Digestion of capelin, Mallotus villosus (Müller), herring, Clupea harengus L., and polar cod, Boreogadus saida (Lepechin), otoliths in a simulated seal stomach
Authors: Christiansen Jørgen S. , Gamst Moen Anne-Grethe , Hansen Thomas H. , Nilssen Kjell T. 
Published: December 2004

Abstract
The ability of otoliths to withstand digestion in a seal stomach appears to differ between fish taxa with the otoliths of gadoids being particularly resistant to gastric erosion. Few studies have examined the effect of otolith size on the rate of otolith dissolution. We exposed 50 otoliths (total sagittal length: 1.4–7.0 mm) from capelin (Mallotus villosus, n = 20), herring (Clupea harengus, n = 10), and polar cod (Boreogadus saida, n = 20) as well as nine whole capelin (total body length = 100–120 mm) to digestive solutions assumed to mimic the gastric environment of Arctic seals in vitro (pH: ∼2, temperature: ∼37°C, pepsin concentrations: 0–750-μg ml−1 solution). Pepsin did not affect the dissolution rates of sagittae but resulted in a complete digestion of whole capelin within 10 h. Irrespective of species examined, sagittae fitted the same pattern of dissolution rate with the smaller sagittae being dissolved faster than did the larger ones. We suggest that scaling controls sagittal dissolution rates (DR, μm min−1), and that the sagittae from the three forage fish combined dissolve according to sagittal length (SL, mm) as shown by the equation: DRCommon = 27.348e−0.120 SL (n = 46, r2 = 0.688, p < 0.001). Given this relationship, the numerical importance of prey taxa with the smaller otoliths – i.e. also the small-sized gadoids (polar cod) – is likely to be underestimated in feeding studies with Arctic seals.
An assessment of the upstream migration and reproductive behaviour of allis shad (Alosa alosa L.) using acoustic tracking
Authors: Acolas M.L. , Bégout Anras M.L. , Véron V. , Jourdan H. , Sabatié M.R. , Baglinière J.L. 
Published: December 2004

Abstract
We provide a detailed description of the migratory and reproductive behaviour of allis shad (Alosa alosa L.), a species that is in decline in Europe. Adult swimming behaviour during the last part of upstream migration and on a spawning ground downstream of an insurmountable dam was studied in detail and its main features identified, “characterized” in this context. Mobile telemetry and a fixed telemetry system were used to record fish positions and to monitor 23 acoustically tagged individuals (17 females and six males) during the 2001 and 2002 reproductive seasons. Allis shad showed considerable exploratory behaviour, and a rest area was observed 1.5 km downstream of the spawning ground. Thirteen individuals were observed on the spawning area, though both males and females spent most of their time (70–99%) away from it. Male and female residency times on the spawning area were, respectively, 1–11 days and 1–7 days, and females were observed during both day and night on the spawning ground. In 2002, an analysis of the 3D swimming behaviour on the spawning ground of six individuals allowed us to estimate the number of spawning events per fish. Males participated in more spawning acts (up to 60) than females (0–2).