bluuebunny/crossref_metadata_2025_split huggingface dataset:
« La grenouille et le bœuf » ? Ascension frauduleuse, patrimoine et chute d’un facteur d’une super compagnie (Silimanni vs Peruzzi, Florence, 1330)
Authors: Quertier Cédric 
Published: November 2023

« La grenouille et le bœuf » ? Ascension frauduleuse, patrimoine et chute d’un facteur d’une super compagnie (Silimanni vs Peruzzi, Florence, 1330)En novembre-décembre 1330, trois sentences pour faillite sont rendues contre les frères Silimanno et Giovanni di Lottieri Silimanni, à la demande de Tommaso Peruzzi. De manière singulière, l’une d’elles contient une longue liste d’objets saisis et une autre version mentionne le prix individuel des objets. Ces procès évoquent l’ascension fulgurante d’un facteur de la filiale anglaise de la compagnie des Peruzzi. Or, les interrogatoires révèlent qu’elle est fondée sur le détournement massif de métaux précieux et de monnaies, avec la complicité d’orfèvres et de sa famille dans une période de crise qui menace la sécurité de la compagnie.Ces procès ouvrent ainsi une fenêtre sur la richesse matérielle des acteurs intermédiaires du commerce d’une des plus grandes métropoles économiques européennes. Elle interroge également sur les moyens qui auraient été nécessaires pour faire perdurer cette fortune car la chute des Silimanni est aussi rapide que leur ascension.Après avoir présenté les protagonistes, nous détaillons la nature de la fraude, avant d’exposer la composition de la fortune mobilière de Silimanno et d’achever par l’examen du procès de son frère Giovanni, infâme parmi les grands marchands, capable de fréquenter les milieux carcéraux comme de fournir les plus grandes familles.
Estimer les fortunes rouennaises à la fin du Moyen Âge : sources et méthodes
Authors: Kucab Anne 
Published: November 2023

Les listes de biens conservés à Rouen pour la seconde moitié du xve siècle donnent peu de prix, elles détaillent toutefois précisément les biens meubles possédés. Elles sont de ce fait un support intéressant pour estimer les fortunes rouennaises en les croisant avec les sources comptables conservées de la ville. Il s’agit dans cet article de proposer une réflexion méthodologique sur l’estimation des fortunes d’après les listes de biens. Ces biens sont parfois négligés alors qu’ils délivrent des indications sur le niveau de vie de leur propriétaire. Cet article cherche à attirer l’attention sur ces éléments. Nous articulerons notre propos autour de deux exemples principaux : le couchage et le linge de maison.
Christine de Pizan, l’Église et la construction du politique
Authors: Rodriguez Juliana Eva 
Published: November 2023

Dans la pensée politique de Christine de Pizan, on se trouve face à une absence notoire : l’Ecclesia en tant qu’institution du pouvoir. Ce qui étonne, lorsqu’on observe les traités politiques de l’époque médiévale, dans lesquels la question du rapport entre pouvoir spirituel et pouvoir temporel est un lieu commun, principalement avec la réforme grégorienne et la querelle entre Boniface VIII et Philippe Le Bel. Mais au-delà de ces clivages historiques, cette tension entre la monarchie et l’Église demeure un problème latent tout au long du Moyen Âge. Et il ne faut pas oublier que si les temps de Christine sont ceux de la guerre de Cent Ans et de la guerre civile, ce sont aussi ceux du Grand Schisme, où l’on voit ressurgir les anciens rêves de monarchie universelle, y compris une redéfinition des pouvoirs en concurrence. Ceux du pape, de l’empereur, du roi, des évêques, des cardinaux et du concile sont tous reformulés à la lumière des anciennes comme des nouvelles théories. Pourtant, cette tension entre Église et monarchie ne semble en aucun cas faire partie de la réflexion de Christine sur le pouvoir royal. Cet article se propose de montrer quelques traces de cette « absence » de l’Église dans les écrits politiques de l’écrivaine et d’avancer quelques hypothèses à ce sujet.
L’écriture de l’histoire dans le monde anglo-normand médiéval : autour de quelques publications récentes
Authors: Paquet Fabien 
Published: November 2023

Depuis quelques années, les mondes anglo-normands médiévaux sont un terrain fertile pour les recherches sur les écritures médiévales de l’histoire, que ce soit à travers les pratiques de quelques auteurs phares (Dudon de Saint-Quentin, Orderic Vital, Guillaume de Malmesbury, Robert de Torigni, Gervais de Cantorbéry…) ou de celles d’auteurs anonymes, qui permettent aussi d’interroger les frontières entre les genres historiques. À partir de quelques publications récentes, ce « point de vue » propose de tirer quelques grandes dynamiques actuelles, de faire dialoguer des travaux menés des deux côtés de la Manche et de les replacer dans un contexte plus large, au croisement des études historiques et littéraires.
The Microbial Tryptophan Metabolite Contributes to the Remission of Salmonella typhimurium Infection in Mice
Authors: Li Yingying , Li Junqi , Jia Dan , Gao Shandian , Guo Yanan , Liu Junlong , Wang Jinming , Guan Guiquan , Luo Jianxun , Yin Hong , Xiao Sa , Li Youquan 
Published: November 2023

Abstract
Salmonella enterica serovar Typhimurium (S. Tm) causes severe foodborne diseases. Interestingly, gut microbial tryptophan (Trp) metabolism plays a pivotal role in such infections by a yet unknown mechanism. This study aimed to explore the impact of Trp metabolism on S. Tm infection and the possible mechanisms involved. S. Tm–infected C57BL6/J mice were used to demonstrate the therapeutic benefits of the Bacillus velezensis JT3-1 (B. velezensis/JT3-1) strain or its cell-free supernatant in enhancing Trp metabolism. Targeted Trp metabolomic analyses indicated the predominance of indole-3-lactic acid (ILA), an indole derivative and ligand for aryl hydrocarbon receptor (AHR). Based on the 16S amplicon sequencing and correlation analysis of metabolites, we found that B. velezensis supported the relative abundance of Lactobacillus and Ligilactobacillus in mouse gut and showed positive correlations with ILA levels. Moreover, AHR and its downstream genes (especially IL-22) significantly increased in mouse colons after B. velezensis or cell-free supernatant treatment, suggesting the importance of AHR pathway activation. In addition, ILA was found to stimulate primary mouse macrophages to secrete IL-22, which was antagonized by CH-223191. Furthermore, ILA could protect mice from S. Tm infection by increasing IL-22 in Ahr+/− mice, but not in Ahr−/− mice. Finally, Trp-rich feeding showed amelioration of S. Tm infection in mice, and the effect depended on gut microbiota. Taken together, these results suggest that B. velezensis–associated ILA contributes to protecting mice against S. Tm infection by activating the AHR/IL-22 pathway. This study provides insights into the involvement of microbiota-derived Trp catabolites in protecting against Salmonella infection.
Conditional NKT Cell Depletion in Mice Reveals a Negative Feedback Loop That Regulates CTL Cross-Priming
Authors: Heuser-Loy Christoph , Baumgart Ann-Kathrin , Hackstein Carl-Philipp , Courrèges Christina J F , Philipp Marie-Sophie , Thaiss Christoph A , Holland Tristan , Evaristo César , Garbi Natalio , Kurts Christian 
Published: November 2023

Abstract
NKT cells are unconventional T cells whose biological role is incompletely understood. Similar to TH cells, activated NKT cells can cause dendritic cell (DC) maturation, which is required for effective CTL responses. However, it is unclear whether and how NKT cells affect CTLs downstream of the DC maturation phase. This is partially due to the lack of techniques to conditionally deplete NKT cells in vivo. To overcome this problem, we have developed two approaches for this purpose in mice: the first is based on mixed bone marrow chimeras where Jα18 knockout and depletable CD90 congenic bone marrow is combined, and the second used PLZFCre × iDTR bone marrow chimeras, which target innate-like T cells. Using these tools, we found that NKT cell depletion at 20 h, that is, after initial DC activation, did not render CTLs helpless, as CD40L signaling by non-NKT cells sufficed. Instead, NKT cell depletion even augmented CD8 T cell expansion and cytotoxicity by mechanisms distinct from reduced STAT6 signaling. These findings revealed a negative feedback loop by which NKT cells control CTL cross-priming downstream of DC maturation. The techniques described in this study expand the toolbox to study NKT cells and other unconventional T cell subsets in vivo and uncovered a hidden immunoregulatory mechanism.
Mental health symptoms and illness trajectory following COVID-19 hospitalization: A cohort study
Authors: Lomholt-Welch Harriet , Morrow Andrew J. , Sykes Robert , Saleh Merna , Zahra Baryab , MacIntosh Alasdair , Kamdar Anna , Bagot Catherine , Bayes Hannah K. , Blyth Kevin G. , Bulluck Heerajnarain , Carrick David , Church Colin , Corcoran David , Findlay Iain , Gibson Vivienne B. , Gillespie Lynsey , Grieve Douglas , Barrientos Pauline Hall , Ho Antonia , Lang Ninian N. , Lowe David J. , Lennie Vera , Macfarlane Peter W. , Mayne Kaitlin J. , Mark Patrick B. , McConnachie Alex , McGeoch Ross , Nordin Sabrina , Payne Alexander , Rankin Alastair J. , Robertson Keith , Ryan Nicola , Roditi Giles , Sattar Naveed , Stobo David , Allwood-Spiers Sarah , Touyz Rhian M. , Veldtman Gruschen , Weeden Sarah , Weir Robin , Watkins Stuart , Welsh Paul , Mangion Kenneth , Berry Colin 
Published: November 2023

Background:
The multisystem associations between baseline mental health status and coronavirus disease-19 (COVID)-19 illness trajectory are uncertain.

Objectives:
This article will investigate the associations between baseline mental health status and disease trajectory following COVID-19 hospitalization, which may have implications for practice and future research.

Methods:
The Chief Scientist Office Cardiovascular and Pulmonary Imaging in severe acute respiratory syndrome (SARS) COVID-19 study is a prospective, observational, multicenter, longitudinal, secondary care cohort study that assessed the time-course of multi-organ injury in posthospital survivors of COVID-19. Patients were assessed in-hospital, at 28–60 days after discharge and in the longer term using electronic health record linkage.

Results:
One hundred and fifty-two patients (mean ± standard deviation [SD] age 54.3 ± 11.8 years, 43% female, 40% most socio-economically deprived quintile, 33% history of mental health history) were enrolled and had mental health serially assessed using the Patient Health Questionnaire-4 (PHQ-4) questionnaire. Fifty-three (35%) had PHQ-4 score of 6–12 consistent with moderate-severe symptoms of anxiety or depression and this was associated with diagnostic criteria for myocarditis (P = 0.0498). Moderate-severe symptoms of anxiety or depression were positively associated with higher perception of illness, lower health-related quality of life (HRQoL), and poorer physical function. The mean (SD) duration of follow-up after hospital discharge was 428 (86) days (range, 290–627 days). PHQ-4 score was not associated with clinical outcomes at follow-up.

Conclusions:
In patients who have been hospitalized with COVID-19, moderate-severe symptoms of anxiety or depression were associated with myocarditis, worse HRQoL, higher perception of illness, and lower levels of physical function.

Public Registration:
ClinicalTrials.gov identifier is NCT04403607.
Prevalence of alcohol dependence syndrome in the patients of acute pancreatitis: A cross-sectional study
Authors: Bajwa Manpreet Kaur , Chauhan Vinay S. , Nath Shubhranshu , Singh Kartikeya R. , Banyal Navdeep , Panjrattan Carol 
Published: November 2023

Background:
Acute pancreatitis (AP) is the main reason for mortality and morbidity. Numerous studies have shown a link between chronic alcohol usage and AP. However, there are few studies on the percentage of patients developing AP as a result of dependent patterns of drinking and associated risk factors.

Aim:
This study aimed to study the prevalence and impact of risk factors of alcohol dependence syndrome with AP patients hospitalized in tertiary care facilities.

Materials and Methods:
This is a cross-sectional observational study. Sociodemographic and clinical data were taken from patients with AP after consent. Eighty-five patients with AP who met the inclusion criteria were involved after each participant had clinical evaluation using the modified Marshall score, the Alcohol Use Disorder Identification Test, and the Severity of Alcohol Dependence Questionnaire (SAD-Q). The outcomes were tabulated and analyzed using Statistical Package for the Social Sciences (SPSS) software.

Results:
38.8% of patients with AP were found to have features of alcohol dependence syndrome. Higher values of mean corpuscular volume (MCV), serum glutamic-oxaloacetic transaminase (SGOT), serum glutamic pyruvic transaminase (SGPT), Gamma-glutamyl transferase (GGT), and uric acid were associated with a greater propensity to have AP. The severity of alcohol dependence syndrome and AP was not associated.

Conclusion:
AP is potentially a fatal disease. In this study, 38.8% of AP patients had alcohol dependence syndrome. There was no statistical association between the severity of AP and alcohol dependence syndrome, though high values of MCV, SGOT, SGPT, and GGT were at greater risk of developing AP. As a result, alcohol dependence syndrome should be examined in all individuals with AP.
Dyslexia: An invisible disability or different ability
Authors: Sunil Akhila B. , Banerjee Amitav , Divya Madamanchi , Rathod Hetal K. , Patel Jhanvi , Gupta Medhavi 
Published: November 2023

Background:
With a global dyslexia prevalence of at least 10%, significant numbers of students with dyslexia go undiagnosed and their symptoms unaddressed, but with timely intervention, 90% of dyslexic children can be educated in regular inclusive classrooms.

Aim:
This study aimed to estimate the prevalence of dyslexia among primary schoolchildren in government and private schools.

Material and Methods:
A cross-sectional study on 128 primary schoolchildren attending selected government and private schools in Western Maharashtra was conducted and evaluated using the Search tool, which is a standardized study tool for screening dyslexia. Microsoft Excel and MedCalc version 3.1 were used for data entry and analysis. The prevalence of dyslexia was estimated, and differences between groups were evaluated using appropriate tests.

Results:
Of the total sample size of 128 children, findings showed 10.9% of students as dyslexic, 9.3% as vulnerable, and the remaining 79.8% as non-dyslexic. Of 14 dyslexic children, 10 were found to be from government schools and the remaining four were from private schools.

Conclusion:
The high prevalence of dyslexia even in a small study sample size is a matter of concern and emphasizes the need for extensive research and initiatives, including awareness campaigns among teachers, parents, and school authorities, and the importance of detection of undiagnosed dyslexic children as early as possible and providing them with appropriate interventions.
A study of disability before and after radiotherapy among head and neck cancer patients residing around atomic power plant
Authors: Shekhawat Bharat Singh , Sharma Neeraj , Dhaka Vikas , Yadav Sandhya , Vignesh K 
Published: November 2023

Background:
Head and neck cancer (HNC) is a profoundly distressing condition that can have significant psychological implications. It has the potential to impact various fundamental aspects of an individual's life, resulting in functional impairments and structural deformities depending on the location, size, and route of spread, therefore causing significant disability. Yet, this has not been adequately studied. People residing around areas around the atomic radiation power plant are exposed to radiation, and also, contamination of water sources, including the Chambal River, which is a major source of water needs of this area, may have a role in the pathogenesis and prognosis of cancer patients.

Aim:
This study aimed to study disability in patients with head and neck cancer before and after radiotherapy.

Materials and Methods:
This prospective observational study was conducted in association with the Department of Radiotherapy of a tertiary care hospital in Rajasthan. Fifty consecutive HNC patients aged 18 to 65 years fulfilling inclusion criteria, specifically laid down for the study, constituted the sample of the study. The World Health Organization Disability Assessment Schedule version 2.0 (WHODAS-2.0) was used.

Results:
The mean age of patients was 49.62 years. A statistically significant improvement after radiotherapy was found in disability scores in domains of cognition (2.39 vs. 1.88), self-care (2.39 vs. 1.78), and getting along with people domain (2.38 vs. 1.83).

Conclusion:
Disability improved significantly in patients after radiotherapy in the domains of self-care, getting along with people, and cognition.
Acceptance and commitment therapy as an add-on treatment for the management of patients with obsessive-compulsive disorder
Authors: Akhouri Deoshree , Hamza  , Kumar Shravan , Reyazuddin M. 
Published: November 2023

Background:
Obsessive compulsive disorder (OCD) is a chronic and long-lasting illness affecting approximately 2% of the population. Up to 40%–60% of patients with OCD do not have satisfactory outcomes, thereby leading to disability in performing daily routine activities. Acceptance and commitment therapy (ACT) provides a substitute for old-fashioned psychotherapies, as it involves the client directly experiencing the problematic emotion, that is, anxiety and obsessions in the case of OCD.

Aim:
To observe the effect of ACT on patients with OCD and compare its effect on obsessive compulsive symptoms, thought control, thought and action fusion, acceptance and action, and depression.

Materials and Methods:
A total of 62 patients diagnosed with OCD as per Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) in the age range between 18 and 60 years, having duration of illness less than two years, both male and female, literate and illiterate, hailing from rural and urban background, were included in the study. For pre- and post-assessment Yale-Brown Obsessive and Compulsive Scale (Y-BOCS), Hamilton Depression Rating Scale (HDRS), acceptance and commitment questionnaire, thought control questionnaire, and thought and action fusion questionnaire were used in this study, and ACT was used for management of OCD.

Results:
There is a significant difference between the groups treated with ACT and those treated as usual, on every domain of thought control questionnaire (TCQ) -- distraction (t = 9.07), social control (t = 11.13), worry (t = 11.93), punishment (t = 16.78), and re-appraisal (t = 16.47). Significance is also seen in the thought and action fusion in the moral domain (t = 16.22), the likelihood domain (t = 16.49), and others (t = 9.23). On Y-BOCS, HDRS, and acceptance and action questionnaire (AAQ) both groups show a significant difference between each other.

Conclusion:
The findings of the present study indicate that ACT is a productive method for patients with OCD as it encourages the patient to accept and integrate their lived experiences, challenges effective responses, and recognizes and eliminates the controlling dimensions.
Prosocial behavior, psychological well-being, positive and negative affect among young adults: A cross-sectional study
Authors: Kakulte Arvind , Shaikh Samreen 
Published: November 2023

Background:
Prosocial behaviors are considered important moral and social behavior. Various researchers have found that prosocial behavior increases well-being; research is scarce on the effects of prosocial behavior on psychological well-being, positive and negative affect among adults.

Aim:
The present study investigated the relationship between prosocial behavior, psychological well-being, and positive and negative affect on adults.

Materials and Methods:
The study included 80 adults (19–25 years) males and females. Snowball and incidental sampling method is used for data collection. The tools used for the study are the Prosocial Personality Battery, Ryff's psychological well-being scale, and the positive and negative affect scale.

Results:
A positive correlation was found between prosocial behavior and psychological well-being (0.396 which is significant at 0.01 level). A positive correlation was also observed between prosocial behavior and positive affect (0.274 which is significant at 0.01 level). A negative correlation was found between prosocial behavior and negative affect (−0.191 which is significant at 0.05 level).

Conclusion:
People involved in Prosocial behavior showed a positive correlation with Psychological well-being and positive affect and a negative correlation with negative affects.
Impact of psychiatric comorbidity on quality of life and activities of daily living among patients suffering from chronic kidney disease undergoing hemodialysis
Authors: Goyal Ekram , Puria Alka , Chaudhary Suprakash , Kumar Ajay , Raj Richa , Kumar Sidhartha 
Published: November 2023

Introduction:
Chronic Kidney Disease (CKD) is a debilitating illness that impairs an individual's physical and social functioning and ultimately affects the quality of life (QOL).

Aim:
To determine the impact of psychiatric comorbidity on QOL and activities of daily living in individuals suffering from CKD undergoing hemodialysis.

Materials and Methods:
Fifty subjects suffering from CKD undergoing hemodialysis were consequently enrolled in the department of medicine. Institutional ethics committee permission was obtained before the start of the study. The interview was conducted only after the hemodialysis procedure. Consent was obtained and socio-demographic details were noted in the socio-demographic proforma. Schedule for Clinical Assessment in Neuropsychiatry (SCAN) was used to assess psychiatric comorbidity. QOL was assessed on Short Form-36 (SF-36). Katz Index of Independence of Activities of Daily Living scale (KADL) was used to assess the activities of living of such individuals.

Results:
46% (n = 23) of subjects suffering from CKD had psychiatric co-morbidity. The most common psychiatric disorder observed was moderate depressive disorder (14%, n = 7) followed by adjustment disorder (12%, n = 6). QOL on SF-36 in all eight domains was low compared to the general population. There was a high statistically significant negative impact of psychiatric comorbidity on QOL on eight domains of SF-36 and activities of daily living. (P = 0.001).

Conclusion:
Psychiatric co-morbidity is common in CKD patients on hemodialysis. Quality of life is lower compared to the general population. There is a negative impact of psychiatric co-morbidity on quality of life and activities of daily living.