bluuebunny/crossref_metadata_2025_split huggingface dataset:
Risk factors for methicillin-resistant Staphylococcus aureus colonization in a level-IV neonatal intensive care unit: a retrospective study
Authors: Galuszka Julia Elzbieta , Thomsen Kim , Knudsen Jenny Dahl , Stenkjaer Rikke Louise , Nielsen Rikke , Nielsen Karen Leth , Petersen Andreas , Holzknecht Barbara Juliane , Bartels Mette Damkjaer , Breindahl Morten , Aunsholt Lise 
Published: October 2023

Abstract

Objective:
To identify risk factors associated with methicillin-resistant Staphylococcus aureus (MRSA) colonization in neonatal patients during an MRSA outbreak to minimize future outbreaks.

Design:
Retrospective case-control study.

Setting:
Level-IV neonatal intensive care unit (NICU) at Copenhagen University Hospital, Rigshospitalet, Denmark.

Patients:
Neonates with either MRSA or methicillin-susceptible Staphylococcus aureus (MSSA)

Methods:
Methicillin-resistant Staphylococcus aureus-positive neonates were matched with those colonized or infected with MSSA in a 1:1 ratio. The control group was selected from clinical samples, whereas MRSA-positive neonates were identified from clinical samples or from screening. A total of 140 characteristics were investigated to identify risk factors associated with MRSA acquisition. The characteristics were categorized into three categories: patient, unit, and microbiological characteristics.

Results:
Out of 1,102 neonates screened for MRSA, between December 2019 and January 2022, 33 were MRSA positive. They were all colonized with an MRSA outbreak clone (spa type t127) and were included in this study. Four patients (12%) had severe infection. Admission due to respiratory diseases, need for intubation, need for peripheral venous catheters, admission to shared rooms with shared toilets and bath facilities in the aisles, and need for readmission were all correlated with later MRSA colonization (P < 0.05).

Conclusion:
We identified clinically relevant diseases, procedures, and facilities that predispose patients to potentially life-threatening MRSA infections. A specific MRSA reservoir remains unidentified; however, these findings have contributed to crucial changes in our NICU to reduce the number of MRSA infections and future outbreaks.
Commodification of intangibles in post-IP capitalism: rethinking the counter-hegemonic discourse
Authors: Borghi Maurizio 
Published: October 2023

AbstractIntellectual property (IP) is the legal mechanism that transforms intangible instances into tradeable commodities. While creating the conditions for extraction of value and capital accumulation across all domains of economic and social life, IP law defines at the same time the boundaries of commodification by determining the scope of the public domain. Within this traditional framework, opponents of neo-liberal market expansionism have championed the role of IP doctrines and principles such as fair use, exceptions and limitations. However, new informational capitalism relies primarily on non-IP forms of appropriation and de facto control. To a large extent, commodification of intangibles and capital accumulation is no longer distressed by – and even benefits from – traditional public-domain-enhancing IP doctrines. This challenges traditional IP narratives and calls for a new foundation for a truly counter-hegemonic discourse in IP law.
Salient Indigenous Acts of Resistance in Canada, 2010–2020: Current Trends
Authors: Do Minh 
Published: October 2023

AbstractIndigenous peoples continue to challenge Canadian colonial policies through nonroutine acts of resistance. Sustained scholarly attention on the frequency and characteristics of Indigenous resistance has dropped precipitously, with the time span of this scholarship typically ending by the early 2000s. Research on more recent acts of resistance is directed to small-n case studies. This research note examines Indigenous resistance in Canada between 2010 and 2020 as reported by news articles from the Canadian Broadcasting Corporation (CBC) to identify key characteristics of salient Indigenous resistance: What issue areas were the subject of resistance movements? Which Indigenous communities or groups contributed to acts of resistance? What strategies were employed? The research note's findings suggest that salient acts of resistance rarely result in immediate policy change from the state; instead, resistance has transformative potential to develop Indigenous governance that departs from settler-colonial state processes.
Multiple sediment source infill in a low-accommodation basin: implications for the late Paleozoic sediment routing system in the southeastern Ordos Basin
Authors: Fu Chao , Yu Xinghe , Li Shunli 
Published: October 2023

AbstractLate Paleozoic strata in the southeastern Ordos Basin comprise targeted reservoirs for tight gas exploration. As a typical intracratonic basin, the Ordos Basin is characterized by low-accommodation space and a complex sediment infilling process, which attracts much attention. During the early Permian, the southeast area was fed by sediments from multiple sediment sources, which makes it difficult to identify the pinch-out of the sand bodies and reconstruct the sediment routing system. In this study, we reconstruct the paleo-topography of the late Paleozoic setting using high-resolution 2D and 3D seismic data. Thus, we identify two types of topography: the eastern block is presented as a semiclosed depression, and the western block is observed as a flat platform. Based on detrital zircon U–Pb data and heavy mineral assemblages, we reconstruct the provenance area and show that early Permian sediments originate from the northern margin of the Ordos Basin and from the northern Qinling orogenic belt in the south. By integrating the trace element contents, carbon and oxygen isotope data and sedimentary structure from core samples, we can observe the paleoenvironment and the corresponding facies associations in these blocks. The eastern block was infilled by a prograding delta; the western block was infilled by a tide-dominated delta or a wavy-dominated delta. By using stratigraphic forward modelling, we find that most sediments in the semiclosed setting are progradational and intensely interacted. In contrast, the sediments in the western block present an open setting, infilled and gently interacted. The fine-grained deposits were not easily preserved due to tidal or wave reworking processes in the shallow-water marine setting, and they were transported into deep-water areas. Furthermore, to explore the dominant factors in a pattern of fluvial–deltaic sand bodies formed in the low-accommodation basin, we rebuild the sediment routing system parameters and plot them on a bubble chart. According to the fitness between the depositional volume and the above parameters, we determine the key factors in the routing systems that formed. The results show that the sediment supply has a high relevance to the depositional volume in a semiclosed setting, such as the eastern block, while the terrain height may drive sedimentation in an open marine setting, such as the western block. We demonstrate that two different infill patterns and different sand-body stacking patterns with multiple sediment sources in a low-accommodation basin may serve as a model for similar settings.
Sleep deprivation in development of obesity, effects on appetite regulation, energy metabolism, and dietary choices
Authors: Akhlaghi Masoumeh , Kohanmoo Ali 
Published: October 2023

Abstract
Sleep deprivation, which is a decrease in duration and quality of sleep, is a common problem in today’s life. Epidemiological and interventional investigations have suggested a link between sleep deprivation and overweight/obesity. Sleep deprivation affects homeostatic and non-homoeostatic regulation of appetite, with the food reward system playing a dominant role. Factors such as sex and weight status affect this regulation; men and individuals with excess weight seem to be more sensitive to reward-driven and hedonistic regulation of food intake. Sleep deprivation may also affect weight through affecting physical activity and energy expenditure. In addition, sleep deprivation influences food selection and eating behaviours, which are mainly managed by the food reward system. Sleep-deprived individuals mostly crave for palatable energy-dense foods and have low desire for fruit and vegetables. Consumption of meals may not change but energy intake from snacks increases. The individuals have more desire for snacks with high sugar and saturated fat content. The relationship between sleep and the diet is mutual, implying that diet and eating behaviours also affect sleep duration and quality. Consuming healthy diets containing fruit and vegetables and food sources of protein and unsaturated fats and low quantities of saturated fat and sugar may be used as a diet strategy to improve sleep. Since the effects of sleep deficiency differ between animals and humans, only evidence from human subject studies has been included, controversies are discussed and the need for future investigations is highlighted.
Contemporary transesophageal echocardiography practice patterns among paediatric cardiology centres in the United States and Canada
Authors: Wilson Hunter C. , Ferguson M. Eric , Border William L. , Sachdeva Ritu 
Published: October 2023

AbstractObjective:To characterise transesophageal echocardiography practice patterns among paediatric cardiac surgical centres in the United States and Canada.Methods:A 42-question survey was sent to 80 echocardiography laboratory directors at paediatric cardiology centres with surgical programmes in the United States and Canada. Question domains included transesophageal echocardiography centre characteristics, performance and reporting, equipment use, trainee participation, and quality assurance.Results:Fifty of the 80 centres (62.5%) responded to the survey. Most settings were academic (86.0%) with 42.0% of centres performing > 350 surgical cases/year. The median number of transesophageal echocardiograms performed/cardiologist/year was 50 (26, 73). Pre-operative transesophageal echocardiography was performed in most surgical cases by 91.7% of centres. Transesophageal echocardiography was always performed by most centres following Norwood, Glenn, and Fontan procedures and by < 10% of centres following coarctation repair. Many centres with a written guideline allowed transesophageal echocardiography transducer use at weights below manufacturer recommendations (50.0 and 61.1% for neonatal and paediatric transducers, respectively). Most centres (36/37, 97.3%) with categorical fellowships had rotations which included transesophageal echocardiography participation. Large surgical centres (>350 cases/year) had higher median number of transesophageal echocardiograms/cardiologist/year (75.5 [53, 86] versus 35 [20, 52], p < 0.001) and more frequently used anaesthesia for diagnostic transesophageal echocardiography ≥ 67% of time (100.0 versus 62.1%, p = 0.001).Conclusions:There is significant variability in transesophageal echocardiography practice patterns and training requirements among paediatric cardiology centres in the United States and Canada. Findings may help inform programmatic decisions regarding transesophageal echocardiography expectations, performance and reporting, equipment use, trainee involvement, and quality assurance.
Coronary artery dilation in non-hospitalised children with asymptomatic or mild COVID-19
Authors: Gerber Nicole , Lutrario Christopher , Rosenthal Michelle , Platt Shari , Holzer Ralf , Flynn Patrick 
Published: October 2023

AbstractIntroduction:Infection with Sars-CoV-2 is known to cause cardiac injury and coronary artery changes in moderate to severe acute COVID-19 and post-acute multisystem inflammatory syndrome in children (MIS-C). However, little is known about the potential for cardiac involvement, in particular coronary artery dilation, in asymptomatic or mild cases of COVID-19.Methods:A retrospective review of children ≤ 18 years of age with a history of asymptomatic or mild COVID-19 disease who underwent echocardiography after Sars-CoV-2 infection is conducted. Patients were excluded if they had been hospitalised for COVID-19/MIS-C or had a history of cardiac disease that could affect coronary artery dimension. Coronary artery dilation was defined as the Boston Z-score greater than 2.0.Results:One hundred and fifty-seven patients met inclusion criteria with a mean age of 9.4 years (+/– 5.4 years). Eighty-four (54%) patients were identified as having COVID-19 through positive antibody testing. All patients underwent electrocardiogram and echocardiogram as part of their cardiology evaluation. One hundred and thirty-five (86%) patients had a normal evaluation or only a minor variant on electrocardiogram, while 22 patients had abnormalities on echocardiogram, 4 of which demonstrated coronary artery dilation based on the Boston Z-score.Conclusions:Much of the literature for post-infectious screening and follow-up focuses on patients with a history of moderate to severe COVID-19 disease, emphasising the need for surveillance for the potential development of myocarditis. In this study, 4 out of 157 (2.5%) children with a history of asymptomatic or mild COVID-19 disease without MIS-C were found to have some degree of coronary artery dilation. The significance of this finding currently remains unknown.
Hominin Response to Oscillations in Climate and Local Environments During the Mid‐Pleistocene Climate Transition in Northern China
Authors: Zhou Bin , Wang Zhe , Xu Xiangchun , Pang Yang , Bird Michael I. , Wang Bin , Meadows Michael E. , Taylor David 
Published: October 2023

AbstractArcheological evidence from loess sediments from Shangchen on the southeastern Chinese Loess Plateau indicates a suspension of hominin occupation around the time of the early mid‐Pleistocene climate transition, prompting a re‐assessment of climate‐vegetation‐hominin interactions. Loess deposits with in situ lithic records cover the period of hominin occupation and reveal four distinct climate‐vegetation periods (2.1–1.8, 1.8–1.26, 1.26–0.9, and 0.9–0.6 Ma). Major oscillations in climate superimposed upon an aridification trend and an expansion of C4 herbaceous vegetation from about 1.26 Ma may have driven early humans to move to more hospitable locations in the region. Comparison with the record at Nihewan indicates that large‐scale climate oscillations induced disparate hominin responses due to distinctive local environmental conditions.
Steady‐State Bedrock Channel Width
Authors: Li Tingan , Venditti Jeremy G. , Sklar Leonard S. 
Published: October 2023

AbstractThe increase in bedrock channel width and the decline in bedrock channel slope with increasing drainage area are fundamental characteristics of mountainous landscapes. Compared with slope, little is known about controls on steady‐state bedrock channel width. We model steady‐state bedrock channel width by iteratively solving models for bed and bank erosion by impacting bedload, using measurable physical parameters, including uplift rate, water discharge, sediment supply, grain size, rock strength, and bank angle. The results indicate that width is largely controlled by sediment flux, rather than water discharge. The commonly used width‐discharge scaling relation is an artifact of the covariance of sediment flux and water discharge. Scaling up from cross‐section to drainage basin scales, our model reproduces the width‐drainage area scaling relation and suggests that the scaling exponent is largely controlled by the downstream change in the fraction of total sediment supply transported as bedload.
Mass Extinction Coincided With Expanded Continental Margin Euxinia During the Cambrian Age 4
Authors: Chang Chao , Hu Wenxuan , Huang Kang‐Jun , Wang Zhenfei , Zhang Xingliang 
Published: October 2023

AbstractEarth's biosphere witnessed the first major extinction event in the Phanerozoic during the Cambrian Age 4, with a genera loss up to ∼45%. The traditional view suggested that marine anoxia was the main cause of the biotic crisis, yet recent geochemical investigations yielded highly debated opinions on marine redox states during the Cambrian Age 4. Herein, we supplement new geochemical evidence for expanded marine euxinia at the extinction intervals on the Yangtze Platform, South China. Most importantly, modern‐level sedimentary δ98Mo (∼+2.34‰) records were most parsimoniously explained by transitory expansion of continental margin euxinia and concomitant intensification of sedimentary Mo sequestration via Fe‒Mn shuttles in the global ocean. The results clarify global marine redox conditions during the Cambrian Age 4, and lend firm support to a causal link between expanded marine euxinia and the extinction event.
Identification of Growth Strata: New Insights From Anisotropy Corrected Paleomagnetic Data
Authors: Sun Xinxin , Tong Yabo , Yang Zhenyu , Pei Junling , Zhang Zijian , Hou Lifu 
Published: October 2023

AbstractGrowth strata are important for understanding regional tectonic evolution. However, it is difficult to identify growth strata in the field, because of subsequent intensive modification and erosion. To address this problem, we studied two paleomagnetic sections at the stable deposition setting and the growth end of the Miocene growth strata of the Gengma Basin. Average inclinations of the two sections show a systematic deviation of 4.7° ± 5.2°. The anisotropy of magnetic susceptibility results for the growth end of the section A demonstrate a sedimentary fabric. However, the tilt‐corrected K3 axis deviates to the southwest from the normal direction of the bedding by 5.4° ± 3.8°, the magnetic foliation deviates to the equatorial plane by 5.3° ± 4.7°. The K3 axis is perpendicular to the bedding at the stable deposition setting. The deviation of the K3 axis from the normal direction of bedding is interpreted as the growth angle, which can be used to correct the paleomagnetic inclination data.
Filtering of the Signal of Sediment Export From a Glacier by Its Proglacial Forefield
Authors: Mancini D. , Dietze M. , Müller T. , Jenkin M. , Miesen F. , Roncoroni M. , Nicholas A. P. , Lane S. N. 
Published: October 2023

AbstractAlpine glaciers are rapidly retreating due to global warming and this has been associated with enhanced supply of subglacially derived sediment to downstream environments. We present the first high frequency quantitative record on how the signal of sediment exported from an Alpine glacier is filtered by its proglacial forefield. The data, covering two climatically distinct glacier melt seasons, show that the signal of subglacial bedload export is strongly filtered over short distances, unlike suspended load whose signal is less impacted. The reason is related to the interplay of short particle advection lengths with strong morphodynamic forcing. The subglacial sediment export signal is thus rapidly replaced by one combining (a) the local forcing by stream hydraulics and (b) the reworking of the proglacial braid plain itself. These findings have implications for estimating subglacial erosion rates, natural hazard mitigation, sediment management for hydropower plants and ecological succession related to rapid glacier retreat.
Ionosphere Heterogeneities at Dawn−Dusk Terminator Related to the Starlink Satellites Launch Disaster on 3−8 February 2022
Authors: Gulyaeva Tamara , Lukianova Renata , Haralambous Haris 
Published: October 2023

AbstractWe present an analysis of the evolution of the ionospheric Total Electron Content (TEC) and its variability index Vσ during the Starlink launch disaster on 3–8 February 2022 two‐phase geomagnetic storm. JPL GIM‐TEC global maps with increased spatial (1° in latitude and longitude) and temporal (15 min cadence) resolution as well as SWARM satellite data have been used in the analysis. Comparison of data for five time periods including Starlink launches with geomagnetic Dst index demonstrates thermospheric mass densities increasing by about 50% during the development of the storm on 3–5 February. A spectrum periodogram analysis is applied on TEC at sunrise and sunset solar terminator (STh) at an altitude h = 300 km. Periodicities in the solar terminator TEC generated waves are estimated as 24 hr, 12 hr, 1 hr, 30 min, 20 min, and 15 min. A significant morning−evening asymmetry resulted in the density anomalies concentrated in a certain—evening—sector of terminator when plasma is shifted to the dusk side forming a global asymmetry.
Simultaneous entry as an adaptation to virulence in a novel satellite-helper system infecting Streptomyces species
Authors: deCarvalho Tagide , Mascolo Elia , Caruso Steven M , López-Pérez Júlia , Weston-Hafer Kathleen , Shaffer Christopher , Erill Ivan 
Published: October 2023

Abstract
Satellites are mobile genetic elements that are dependent upon the replication machinery of their helper viruses. Bacteriophages have provided many examples of satellite nucleic acids that utilize their helper morphogenic genes for propagation. Here we describe two novel satellite-helper phage systems, Mulch and Flayer, that infect Streptomyces species. The satellites in these systems encode for encapsidation machinery but have an absence of key replication genes, thus providing the first example of bacteriophage satellite viruses. We also show that codon usage of the satellites matches the tRNA gene content of the helpers. The satellite in one of these systems, Flayer, does not appear to integrate into the host genome, which represents the first example of a virulent satellite phage. The Flayer satellite has a unique tail adaptation that allows it to attach to its helper for simultaneous co-infection. These findings demonstrate an ever-increasing array of satellite strategies for genetic dependence on their helpers in the evolutionary arms race between satellite and helper phages.