bluuebunny/crossref_metadata_2025_split huggingface dataset:
ALTERACIÓN QUÍMICA DE LOS FRAGMENTOS DE MATRIZ Y DE LOS VIDRIOS VOLCÁNICOS DE LOS SUELOS Y PALEOSUELOS ÁNDICOS DEL NORTE DE LA CORDILLERA CENTRAL COLOMBIANA
Authors: M.T. Flórez M. , Zapata R. , Malagón D. , Madriñán R. 
Published: November 2023

Los diferentes componentes de las cenizas volcánicas no tienen igual susceptibilidad a meteorizarse, ello es evidente por los resultados obtenidos en esta investigación. Se tomaron fragmentos de matriz (FM), vidrios volcánicos coloreados (VVC) y vidrios volcánicos incoloros (VVI) y se sometieron a disolución durante 625 días en ácido húmico (AH), en agua acidulada (AA) y en ácido oxálico (AO). Se observó que los FM presentan mayor superficie específica, mayor superficie de reacción, mayor número de rasgos de alteración superficial y producen mayores cantidades de iones de Al3+, Si4+ y Fe3+, por ende, son los más susceptibles de ser meteorizados, siguen a estos los VVC y luego los VVI. Durante la experimentación (625 días), la mayor disolución se produce a un rango de pH entre 6.0-7.2; de los tres reactivos, el AH es el que más disuelve a los materiales seguido por el AA o el AO que se comportan de manera diferente, durante el primer y tercer ciclo la relación es: AH>AA>AO, en el segundo ciclo la relación es: AH>>AO>AA.
La mayoría de los valores experimentales obtenidos de la disolución se ubican dentro del campo de estabilidad de la imogolita. Al disminuir la actividad del H4SiO4 y el pH, se posibilita en algunos casos, la formación de gibsita y el sistema se acidifica. Cuando disminuye la actividad del H4SiO4 y aumenta la del Al3+, unos pocos valores se mueven hacia los valores teóricos de la actividad de la haloisita. A medida que aumenta la actividad del H4SiO4 y disminuye la del Al3+ los valores se acercan hacia los valores teóricos de la actividad de la imogolita, mineral que presenta la menor relación de actividades, es el más estable, el que menos se disuelve y presenta menor energía libre. Los diversos reactivos tienen un efecto particular sobre las velocidades de disolución de los FM, los VVC y los VVI y en la producción de los iones Al3+, Si4+ y Fe3+. En los tres ciclos, los FM liberan iones de Al3+ y Si4+ a una velocidad mayor que la de los VVC y la velocidad de éste es mayor que la de los VVI. Las velocidades para liberar Fe3+ son más altas en los VVI y en los VVC que en los FM.
Examining Emancipated Curriculum Development in Middle Schools: A Case Study
Authors: Kapitariyani Kimpo Ellen  , Lala Bumela Sudimantara  
Published: November 2023

Indonesia's education system has been facing a significant learning crisis, as evidenced by the country's declining scores in the 2018 PISA results and its expected drop in the English Proficiency Index ranking in 2022. To tackle this challenge, Indonesia has introduced an Emancipated Curriculum that aims to transform learning in the country. The Emancipated Curriculum is designed to be student-centered, differentiated learning, project-based learning, exploratory learning, and holistic learning. This study discusses the discussion of the Kurikulum Merdeka, school perceptions about the meaning of the Independent Curriculum, implementation in secondary schools. This research uses qualitative research with a case study method. The data in this research was obtained from interviews and documents. The findings show that teachers plan the curriculum with a focus on critical and creative thinking, develop their own learning materials to enhance students' cognitive abilities, and make changes to syllabi and lesson plans. However, the study also reveals that the learning media being developed is not yet digital, which may hinder the effective implementation of the Emancipated Curriculum. Furthermore, traditional learning approaches still dominate the assessment and learning processes. Overall, this study sheds light on the development of the Emancipated Curriculum and highlights the need for further research in this area.
The Phenomenon of Child Marriage in the Pandemic Based on Legal, Social and Health Studies
Authors: Sari Rosnida , Rif'ah Erwin Nur , Wildana Dina Tsalist 
Published: November 2023

This research reviews the phenomenon of child marriage during the pandemic, from a legal, social and health perspective. Based on data from UNICEF, Indonesia ranks eighth in the world with the number of child marriages reaching 1.4 million children. Data on child marriage from the 2018 National Socio-Economic Survey recorded that the number of child marriages in Indonesia was quite high, reaching 1,220,900 incidents. This means that about 1 in 9 women aged 20-24 get married before the age of 18. This research was conducted in Jember Regency by taking 17 representations in 9 sub-districts. This study uses a qualitative method with an observation and interview approach. From the results of the study, it was found that a small proportion of informants were legally married at Religious Affair Office because they had not met the minimum age for marriage, which was 19 years. Some informants applied for a marriage dispensation at the Religious Courts, and some falsified the date of birth by increasing the age so that it meets the minimum age for marriage. Before getting married, a small number of informants got engaged first and most of them did not go through the engagement process. Informants who are engaged are usually engaged for a relatively long time, between 10 months to a year and then get married. Child marriage is against fundamental rights and freedom of children. The recommendation from this study is the need for more intense socialization about the rules of marriage age and the dangers of early marriage, especially related to their health.
TRANSFORMASI PENGETAHUAN DAN REALITAS SOSIAL PELAKU UMK TENTANG LABEL HALAL
Authors: Purnama Muhammad Yuga , Ulinnuha Roma 
Published: November 2023

<p><em>This article discusses the challenges of Small Micro Enterprises (MSEs) in handling halal disruption. In the modern halal era, it is not only a matter of a stable taxonomy between what is permissible (halal) and what is not permissible (haram), but more broadly it has become a form of standardization to manage production, trade and consumption. This system can be a profitable innovation opportunity as well as a disruption for business actors, especially MSEs. The method used is a case study with interviews, observation, and documentation of the MSEs of traditional food and beverages in Sleman. The results show that MSEs experience problems with adaptation to halal certification due to existing social realities such as barriers to information, finance, infrastructure and technology. Efforts are needed to form a social reality that supports the adaptation of MSEs to halal certification such as optimizing socialization, mentoring, and other supporting facilities.</em><em></em></p><p> </p><p><strong><em>Keywords</em></strong><strong><em>: D</em></strong><strong><em>isruption, </em></strong><strong><em>H</em></strong><strong><em>alal </em></strong><strong><em>S</em></strong><strong><em>ertification, MSEs</em></strong><strong><em></em></strong></p><p><strong><em> </em></strong></p><h2>Abstrak</h2><p>Artikel ini membahas tantangan Usaha Mikro Kecil (UMK) dalam menghadapi desrupsi halal. Di era modern halal bukan hanya perkara stable taxonomy antara yang boleh (halal) dan tidak boleh (haram), tetapi lebih luas menjadi sebuah bentuk standarisasi untuk mengatur produksi, perdagangan, dan konsumsi. Sistem tersebut dapat menjadi peluang inovasi yang menguntungkan juga sebagai gangguan terhadap pelaku usaha, utamanya UMK. Metode yang digunakan adalah studi kasus dengan wawancara, observasi, dan dokumentasi terhadap UMK makanan dan minuman tradisional di Sleman. Hasil menunjukkan bahwa bahwa UMK mengalami problem adaptasi terhadap sertifikasi halal akibat realitas sosial yang ada seperti hambatan pada informasi, keuangan, infrastruktur dan teknologi. Perlu usaha untuk membentuk realitas sosial yang mendukung adaptasi UMK terhadap sertifikasi halal seperti optimalisasi sosialisasi, pendampingan, dan sarana pendukung lainnya..</p><p> </p><strong>Kata Kunci: Disrupsi, Sertifikasi Halal, UMK</strong>
RELASI SOSIAL DAN KEPERCAYAAN DALAM INDUSTRI JAMU MADURA: STUDI KASUS PERAMU JAMU DAN POLA KONSUMSI MASYARAKAT
Authors: Muarif Samsul , Satriyati Ekna 
Published: November 2023

<p><em>This study aims to examine more deeply Juduh as a from of trust and the relationship between herbalists and Madurese herbal users. Juduh is term of belief in Madurese society. This research is motivated by the fact that the use of herbal medicine in Madurese society is believed to have many benefits. The method in this research is descriptive qualitative with a case study approach. Meanwhile, the data collection techniques are interviews, observations, and documentation. The results of this study found that Juduh is a from of consumer relations and trust in this case it becomes social capital for herbalists so that they can survive in marketing their herbal products. People who are Juduh by drinking herbal medicine will give recommendations to their relatives or people closest to them. The coming of trust in this case is obtained from consumes who are grateful after drinking herbal medicine so that herbalists will gain trust and social relations that can expand the herbal medicine industry.</em></p><p> </p><p><strong><em>Keywords</em></strong><strong><em>: Herbal Concoction, Juduh, Madura, Social Capital</em></strong></p><p><strong><em> </em></strong></p><h2>Abstrak</h2><p>Studi ini memiliki tujuan untuk menelaah lebih dalam terkait <em>Juduh</em> sebagai bentuk kepercayaan dan relasi antara peramu jamu dengan pengguna jamu Madura. <em>Juduh</em> merupakan istilah kepercayaan masyarakat Madura. Penelitian ini dilatarbelakangi atas fakta bahwasannya penggunaan jamu di masyarakat Madura yang dipercaya memiliki banyak manfaat. Metode dalam penelitian ini adalah kualitatif deskriptif dengan pendekatan studi kasus. Sementara itu, teknik pengambilan data berupa wawancara, observasi, dan dokumentasi. Hasil dari penelitian ini didapatkan bahwa <em>Juduh</em> adalah bentuk dari relasi dan kepercayaan konsumen dalam hal ini menjadi modal sosial bagi peramu jamu sehingga bisa bertahan dalam memasarkan produk jamunya. Masyarakat yang <em>Juduh</em> dengan meminum jamu akan memberikan rekomendasi pada saudaranya atau orang terdekatnya. Datangnya kepercayaan dalam hal ini didapatkan dari konsumen yang <em>Juduh</em> setelah meminum jamu, sehingga peramu jamu akan mendapatkan kepercayaan dan relasi sosial yang mampu melebarkan industri jamu.</p><p> </p><p><strong>Kata </strong><strong>K</strong><strong>unci: <em>Juduh</em><em>, Modal Sosial, Madura, Peramu Jamu</em></strong></p><p><strong><em> </em></strong></p>
A Crayfish-inspired Sensor Fusion Platform for Super Additive Integration of Visual, Chemical, and Tactile Information
Authors: Das Saptarshi , Sakib Najam U , Sadaf Muhtasim Ul Karim , Pannone Andrew , Ghosh Subir , Zheng Yikai , Ravichandran Harikrishnan 
Published: November 2023

Abstract
The concept of cross-sensor modulation, wherein one sensor modality can influence or modulate another's response, is overlooked in traditional sensor fusion architectures. By neglecting this aspect, valuable opportunities to enhance the accuracy and robustness of the fused data are missed. In contrast, biological systems often exhibit more efficient and synergistic sensor fusion mechanisms. Aquatic animals such as crayfish serve as remarkable models for multisensory integration, skillfully integrating visual, tactile, and chemical cues to evade predators, locate prey, and engage in mating behavior. Inspired by this, we propose a neuromorphic platform that integrates graphene-based chemitransistors, monolayer molybdenum disulfide (MoS2) based photosensitive memtransistors, and triboelectric tactile sensors to achieve “Super-Additive” responses to weak chemical, visual, and tactile cues and demonstrate contextual response modulation or adaptability, also referred to as “Inverse Effectiveness Effect”. Finally, we use a hypothetical illustration to highlight how crayfish-inspired sensor fusion approach can be transformative for autonomous search vehicles. We hold the view that the concept of bio-inspired sensor fusion can be extended to encompass various sensor modalities, thereby serving a wider array of applications.
To assess weather the external application of traditional Chinese medicine can promote the trabecular bone regeneration and callus fibrous transformation by regulating IL-1, BMP2, TNF-α, TGF and other serum biochemical index AKP.
Authors: Xi-jiang ZHOU , Chao DUAN , Guo-liang CHE , Jun LI , Ming LIU , Chao DENG 
Published: November 2023

Abstract
Objective To assess weather the external application of traditional Chinese medicine can promote the trabecular bone regeneration and callus fibrous transformation by regulating IL-1, BMP2, TNF-α, TGF and other serum biochemical index AKP.
Methods By constructing a rabbit model of closed fracture, the effects of different stages of external application of traditional Chinese medicine on inflammatory factors, serum biochemical indexes and bone marrow morphology were observed..
Results The expressions of inflammatory factors IL-1 and TNF-α in the closed fracture model after external application of traditional Chinese medicine 1, 2, 3 and positive drug treatment were significantly decreased (P < 0.05). The results of HE staining showed that after the 1, 2 and 3 stage of external application of traditional Chinese medicine and the positive drug treatment, new bone trabeculae grew into the bone marrow cavity, granulation tissue formed at the fracture end, and the original callus formed part of the area transformed into fibrous callus. The results of immunohistochemistry showed that the levels of BMP2, TGF and FGF increased during the treatment of bone marrow neogenesis with external application of traditional Chinese medicines in phases 1, 2 and 3 and positive drugs. (P < 0.05). X-ray results showed that the radial fracture line disappeared and gradually recovered after the treatment of Chinese medicine 1, 2, 3 and positive medicine.
Conclusion External application of traditional Chinese medicine can promote trabecular bone regeneration and callus fibrous transformation by regulating inflammatory factors IL-1 and TNF-α, serum biochemical index AKP, and regulating the expression of BMP2, TGF and FGF levels.
Verification of the presence of superabsorbent polymer (SAP) in fresh concrete: results of an interlaboratory study
Authors: Wyrzykowski Mateusz , Schroefl Christof , Toropovs Nikolajs , Lura Pietro , Snoeck Didier , Ribeiro António Bettencourt , De Maeijer Patricia Kara , Moon Juhyuk , Assmann Alexander , Igarashi Shin-Ichi , Klemm Agnieszka , Almeida Fernando C.R. , Boshoff Billy , Erk Kendra A. , Falikman Vyatcheslav , Agostinho Livia Borba , Mechtcherine Viktor 
Published: November 2023

Abstract
New methods are proposed for the verification of the presence of superabsorbent polymers (SAP) in freshly mixed concrete and estimation of SAP quantity. The methods are in general based on flushing concrete with excess water. They allow separating the light, water-sorbed hydrogel particles from the mineral components in the fresh concrete and making these particles available for further tests. Two types of tests are proposed: Test 1 serves for a visual verification of the presence of SAP (qualitative test), while Test 2 enables to quantify the mass of the collected SAP as a proxy of their concentration in concrete (quantitative test). Different procedures are proposed for these two test methods and their performance is evaluated. The testing procedures were scrutinized in an interlaboratory study carried out by 14 participants from 12 countries. All participating groups detected the presence of SAP in the mix using the qualitative procedures (Test 1). Based on this outcome, we suggest that this method should be applied in the field. In contrast, while most participants obtained reasonably reliable results with the quantification procedure of Test 2, some participants reported large errors. Therefore, the quantification method needs to be further refined, starting from the experience gained in this interlaboratory study.
Addressing Bioreactor hiPSC Aggregate Stability, Maintenance and Scaleup Challenges Using a Design of Experiment Approach
Authors: Yehya Haneen , Raudins Sofija , Jensen Jan , Bukys Michael A. 
Published: November 2023

Abstract
Background
Stem cell-derived therapies hold the potential for treatment of regenerative clinical indications. Static culture has a limited ability to scale up thus restricting its use. Suspension culturing can be used to produce target cells in large quantities, but also presents challenges related to stress and aggregation stability.
Methods
Utilizing a design of experiments (DoE) approach in vertical wheel bioreactors, we evaluated media additives that have versatile properties. The additives evaluated are Heparin sodium salt (HS), polyethylene glycol (PEG), poly (vinyl alcohol) (PVA), Pluronic F68 and dextran sulfate (DS). Multiple response parameters were chosen to assess cell growth, pluripotency maintenance and aggregate stability in response to the additive inputs, and mathematical models were generated and tuned for maximal predictive power.
Results
Expansion of iPSCs using 100 ml vertical wheel bioreactor assay for 4 days on 19 different media combinations resulted in models that can optimize pluripotency, stability, and expansion. The expansion optimization resulted in the combination of PA, PVA and PEG with E8. This mixture resulted in an expansion doubling time that was 40% shorter than that of E8 alone. Pluripotency optimizer highlighted the importance of adding 1% PEG to the E8 medium. Aggregate stability optimization that minimizes aggregate fusion in 3D culture indicated that the interaction of both Heparin and PEG can limit aggregation as well as increase the maintenance capacity and expansion of hiPSCs, suggesting that controlling fusion is a critical parameter for expansion and maintenance. Validation of optimized solution on two cell lines in bioreactors with decreased speed of 40 RPM, showed consistency and prolonged control over aggregates that have high frequency of pluripotency markers of OCT4 and SOX2 (> 90%). A doubling time of around 1 to 1.4 days was maintained after passaging as clumps in the optimized medium. Controlling aggregate fusion allowed for a decrease in bioreactor speed and therefore shear stress exerted on the cells in a large-scale expansion.
Conclusion
This study resulted in a control of aggregate size within suspension cultures, while informing about concomitant state control of the iPSC state. Wider application of this approach can address media optimization complexity and bioreactor scale-up challenges.
Mean flow and eddy summer moisture transport downwind of the Tibetan Plateau in reanalysis data and a regional climate simulation
Authors: Kukulies Julia , Li Wenhong , Chen Deliang 
Published: November 2023

Abstract

Understanding the impact of atmospheric variability on climatological mean moisture transport is crucial because moisture transport determines continental water availability as well as convective organization and resulting precipitation. Here, we analyze the mean flow and eddy components of summer moisture transport in the downwind of the Tibetan Plateau (TP), a region that is characterized by interactions between monsoon systems, extratropical circulation, and mountainous weather systems. Using 40 years of ERA5 reanalysis data and a regional WRF simulation, we determine the absolute and relative contributions of mean flow and eddy moisture transport from multi-daily to subdaily scales. We also link these components to large-scale circulation indices, precipitation, evaporation, and mesoscale convective systems (MCSs). The results show that the largest contributions of eddies to the climatological mean moisture transport are found in the immediate downwind region of the TP. Multi-daily eddy transport contributes with 50% to the total eddy transport downwind of the TP, whereas daily to sub-daily eddy transport makes up the other half. Regional precipitation anomalies are dominated by the mean flow component of southerly moisture influxes which in turn are positively correlated with different South Asian summer monsoon indices and negatively correlated with the West Northern Pacific monsoon index. The eddy transport from the south is positively correlated with a lower jet latitude but does not show any significant correlations with precipitation or MCS activity, likely due to the dominant role of the mean flow moisture transport. While the relative contributions of eddies to the climatological mean moisture transport are similar in ERA5 and WRF, the correlations between moisture transport components and large-scale circulation indices are generally weaker in WRF. This suggests that the dynamical downscaling does not significantly change the role of eddy moisture transport averaged for the region, but it resolves processes that decouple the moisture transport from its large-scale forcing.
Acute kidney disease in patients with Covid 19. A prospective, multicenter, multinational study in Latin America
Authors: Lombardi Raúl , Ferreiro Alejandro , Venegas Yanissa , Pereira Mariana , Carlino Cristina , Granado Rolando Claure-Del , Ponce Daniela , Molina Daniel , Zinoveev Agustina 
Published: November 2023

Abstract
Introduction
Acute kidney disease (AKD) is an innovative perspective that enables a more comprehensive description of acute and subacute kidney disorders. This study aimed to evaluate the clinical characteristics of COVID-19 patients based on their AKD stage.
Methods
Observational, prospective, longitudinal, multinational cohort study conducted across five Latin American countries. Adult patients with diagnosis of Covid 19 were included. Upon hospital admission, a urinalysis or urine strip tests was performed. If protein was not detected, a follow-up search was conducted five days later. Patients were classified in four AKD categories: non-kidney disease, only proteinuria, only acute kidney injury (AKI), proteinuria and AKI.
Results
Three hundred and sixty patients were included. AKD was present in 273 patients (75.8%), of whom 142 (52.0%) had only proteinuria, 11 (4.1%) had AKI without proteinuria, and 120 (43.9%) had both proteinuria and AKI. Overall, proteinuria with or without AKI was present in 262 patients (72.8%), with 37 of them developing this condition during their hospital stay which shown a more severe condition. AKI with or without proteinuria occurred in 131 patients (36.4%). AKI was mainly severe, non-oliguric and hospital-acquired. In-hospital mortality increased with the severity of AKD stage: non-kidney disease 9.5%, only proteinuria 22.8%, only AKI 56.7%, and proteinuria plus AKI 53.0% (p = 0.001).
Conclusions
Our data endorse a novel and comprehensive approach based on the concept of AKD. This integrative approach, encompassing the structural and functional continuum of AKI, AKD, and CKD, enables timely interventions and the implementation of preventive and therapeutic strategies.