bluuebunny/crossref_metadata_2025_split huggingface dataset:
Light Intervention Platform for 28,500-psi Environments
Authors: Rodriguez Rafael , Copold Derek , Milkovisch Mark , Babin Christopher , Ramirez Rafael , Ugah Ibrahim 
Published: December 2023

Abstract
An operator, while designing their completion, needed to secure slim electrical-line intervention technologies, including shifting, debris removal, and milling services. Environmental challenges dictated the following requirements for intervention: 28,5000-psi pressure rating, 150°C temperature, 2.313-in. pass-through restriction, and sour service (H2S rating) as required by the operator.
No slim electrical-line intervention technologies existed that met the sour high-H2S, high-pressure, small pass-through restriction requirements. However, upgrading an existing 20,000-psi slim electrical-line instrumented and automated intervention platform was an economical and technically feasible option that would meet the operator's requirements. The slim high-H2S and high-pressure upgrade was achieved by improving the pressure rating of critical components through a combination of using high-performance materials and optimizing the mechanical robustness by removing high-pressure stress concentrations.
Functional and environmental tests were completed to validate the solution.
This paper presents the analysis and development done to arrive at this solution, demonstrating how a flexible intervention architecture can be upgraded to expand its performance capabilities. The solution also enables future possibilities of expanding the platform to additional services such as tubing cutting and restriction navigation at pressures up to 28,500 psi.
A New GOR Forecasting Methodology for Unconventional Reservoirs
Authors: Chen C. , Lumbangaol A. , Zhou H. , Miocevic D. , McMahan N. 
Published: December 2023

Abstract
The producing GOR trend of unconventional wells is a function of the complex interaction of fluid properties, geology, completion design, well spacing/stacking geometry, and operational changes. These complexities bring as an outcome a wide variation of GOR trends with time. This paper introduces a novel normalized forecasting process to build GOR type curves along with the uncertainty ranges. The long-term GOR range is comparable to theoretical PVT model expectations and offset wells with longer production history. The proposed methodology requires integrated multi-discipline efforts and is not a machine-learning modeling process. Groups of wells are selected based on similar geology and fluid properties while removing wells with poor data quality and operational issues. Next the normalized cumulative oil/EUR is introduced to compare the cumulative GOR curves. Empirical models are then generated to fit the GOR curves and forecast long-term GOR trends. A novel approach for terminal GOR range is applied to constrain the results from empirical models. The normalized process creates proven accurate gas predictions compared to the first three years of well performance. Two different approaches are used to validate the forecasted GOR. The first approach is to derive the terminal GOR range with the available PVT report. The second approach is to benchmark with offset wells with long history. Both approaches show the forecasted GOR is within the reasonable range. The normalized forecasting method has been tested for different areas in Delaware and Midland basins, covering a wide GOR range, and demonstrates its robustness in the forecast.
Barriers and enabling factors to reproductive healthcare utilization for women in the sex trade: a qualitative study
Authors: Birger Lior , Benyamini Yael , Goor Yael , Sahar Zohar , Peled Einat 
Published: December 2023

Abstract

Background: Women in the sex trade encounter significant challenges in obtaining reproductive healthcare. Reports of reproductive healthcare for women in the sex trade center on the prevention and termination of pregnancies, yet most women in the sex trade globally experience full term pregnancies and bear children. This study aimed to explore barriers and enabling factors to providing reproductive healthcare for women in the sex trade in Israel.
Methods: We conducted a qualitative study utilizing a grounded theory method. Data were collected through semi-structured interviews, conducted between June 2021 and July 2022. Interviews were conducted with practitioners in healthcare settings (n=20), practitioners in social services settings (n=15), and women in the sex trade who received reproductive health care-related medical services (n=13) in Israel. The interviews were audiotaped, transcribed, and thematically analyzed.
Results: The findings indicated a multilayered structure of healthcare system-related factors and women-related factors. Stigma was noted as a multidimensional barrier, reflected in service providers' attitude towards women in the sex trade, impairing the patient-provider relationship and impeding women's help-seeking. However, the creation of a relationship of trust between the women and healthcare providers enabled better health outcomes.
Conclusions: Based on the findings, we propose recommendations for designing and implementing reproductive healthcare services for women in the sex trade. The recommendations offer to (a) include women with lived experiences in planning and providing reproductive healthcare services, (b) adopt a trauma-informed approach, (c) emphasize nonjudgmental care, (d) train healthcare providers to reduce stigma and bias, and (e) enhance the affordability of health services for women experiencing marginalization.
Saucer blowouts in the coast dune fields of NW Spain, Iberian Peninsula
Authors: Flor Germán Santos , Martínez Patricio 
Published: December 2023

Abstract

Three selected stabilized saucer blowouts in the coast of NW Spain (Iberian Peninsula) are studied under the morphological and sedimentological points of view. The morphologies of these blowouts are characterized: rim, crest, deflation bottom, right (inner and outer) and left (outer and inner) flanks, outer windward and inner lee ward flanks, inner windward and outer lee ward flanks. They are slightly elongated according to the main direction of the prevailing wind. From surficial sand samples, isolines of grain-size parameters such as centile, mean, sorting, skewness, and kurtosis, as well as the mineralogical composition (bioclastic carbonate versus siliciclastic percents) have been considered to establish specific trends. In many cases, isoline contours are adapted to the floor and the sedimentary rim, allowing to deduce the main flow of the wind that contributes to their formation and development of the complex geometry including their granulometry and composition. The average size is coarser in the outer windward and deflation bottom, and minimum in the crest; the sorting is better in the outer lee side and moderate on the bottom; the skewness shows no contrast being only extreme in the inner lee side; less sharp curves are represented on the windward and leeward flanks and crest, and are leptokurtic on the leeward side; carbonate percents are maximum on the outer lee ward side, followed by the bottom, being minimum on the inner windward side. The flank slopes are very high in the outer leeward and internal windward, and moderate in the outer windward and flat in the crest and deflation bottom. A simple model of morphodynamic and sedimentary characterization is proposed.
Impact of Rapid Urbanization on Aquatic Ecosystem Services: A Case Study of Jiuxianghe Watershed in Nanjing, China
Authors: Chen Dongxiang , Hou Xianrui , Li Xiaotian , Feng Jiawei , Wu Shaohua 
Published: December 2023

Abstract

The urbanization process causes the increase of impervious surface, changes the underlying surface, material and energy cycle, and profoundly affects the urban ecosystem. Based on the hydrological process model, we constructed an evaluation framework for water ecosystem services. Taking the Jiuxiang River basin in Nanjing as an example, this study evaluates the process of urban impervious surface growth and hydrological cycle changes from 2000 to 2015, and reveals the impact of urbanization on water ecosystem services. The results showed that the impervious surface of the Jiuxiang River Basin in Nanjing increased rapidly from 2000 to 2015, and the impervious surface density increased from low to high. In the past 15 years, water supply services in urbanized areas have increased by 23.2%, while water regulation services and supply services have decreased by more than 20%, increasing the risk of urban waterlogging. Rapid urbanization changes the flux and stock in the water cycle process of urban ecosystems, which is the mechanism that leads to the decline of water ecosystem regulation services, support services and cultural services. The evaluation framework and technical method of water ecosystem services proposed in this study can provide theoretical basis and technical reference for water ecosystem services research and urban water ecosystem restoration.
Molecular transmission network analysis of newly diagnosed HIV-1 infections in Nanjing from 2019 to 2021
Authors: Shi Hongjie , Li Xin , Wang Sainan , Dong Xiaoxiao , Qiao Mengkai , Wu Sushu , Wu Rong , Yuan Xin , Wang Jingwen , Xu Yuanyuan , Zhu Zhengping 
Published: December 2023

Abstract

Objective
The objective of this study was to conduct a comprehensive analysis of the molecular transmission networks and transmitted drug resistance (TDR) patterns among individuals newly diagnosed with HIV-1 in Nanjing.
Methods
Plasma samples were collected from newly diagnosed HIV patients in Nanjing between 2019 and 2021. The HIV pol gene was amplified, and the resulting sequences were utilized for determining TDR, identifying viral genotypes, and constructing molecular transmission networks. Logistic regression analyses were employed to investigate the epidemiological characteristics associated with molecular transmission clusters.
Results
A total of 1161 HIV pol sequences were successfully extracted from newly diagnosed individuals, each accompanied by reliable epidemiologic information. The analysis revealed the presence of multiple HIV-1 subtypes, with CRF 07_BC (40.57%) and CRF01_AE (38.42%) being the most prevalent. Additionally, six other subtypes and unique recombinant forms (URFs) were identified. The prevalence of TDR among the newly diagnosed cases was found to be 7.84% during the study period. Employing a genetic distance threshold of 1.50%, the construction of the molecular transmission network resulted in the identification of 137 clusters, encompassing 613 nodes, which accounted for approximately 52.80% of the cases. Multivariate analysis indicated that individuals within these clusters were more likely to be aged 60 years or older, unemployed, possess a baseline CD4 cell count greater than 200 cells/mm3, and infected with the CRF105_0107 subtype (P < 0.05). Furthermore, the analysis of larger clusters revealed that individuals aged 60 years or older, peasants, those without TDR, and individuals infected with the CRF105_0107 subtype were more likely to be part of these clusters.
Conclusions
The findings of this study highlight the elevated risk of transmission and spread of the HIV epidemic associated with the CRF105_0107 subtype in Nanjing. Additionally, the high prevalence of TDR among newly diagnosed individuals is a cause for concern. It is crucial to implement targeted interventions that take into account the molecular transmission clusters identified in this study to effectively control the HIV epidemic in Nanjing. Further research should be conducted to explore and develop specific strategies tailored to address the unique challenges posed by these clusters. By doing so, we can mitigate the impact of HIV and reduce its transmission within the population of Nanjing.
Automatic identification of community-onset sepsis among patients attending an emergency department – a validation study
Authors: Duré Cristian , Jonmarker Sandra , Bohm Katarina , Nordqvist Hampus , Joelsson-Alm Eva , Rimling Liivi , Franko Mikael Andersson , Cronhjort Maria , Ängeby Kristian 
Published: December 2023

Abstract

Purpose To develop and validate a software application able to identify cases of community-onset sepsis based on Sepsis-3 criteria among patients visiting an emergency department.Methods An application, developed with the software QlikView®, accessed data from the electronic health record systems TakeCare® and CliniSoft®. It utilized indicators like blood culture data, antibiotic administration, and Sequential Organ Failure Assessment scores to detect sepsis cases likely to fulfil Sepis-3 criteria. The application was tested retrospectively against a cohort from a large city hospital in Stockholm during a period of two years. The performance of the application was compared to physician record review in a subset of cases identified by stratified random sampling.Results Among 229,195 emergency department visits leading to 60,213 hospital admissions, the application detected 7,027 cases of sepsis. Validation using physician record review of totally 426 cases as gold standard demonstrated a sensitivity, specificity, positive predictive value and negative predictive value of 94%, 98%, 92% and 99%, respectively. The lower respiratory tract was the most common site of infection.Conclusion This software application effectively identified community-onset sepsis patients using electronic health record data with high performance. It has the potential to improve sepsis case identification, enable further research on sepsis incidence and mortality, and support adherence to treatment guidelines as well as contributing to enhanced sepsis surveillance and the implementation of quality improvement interventions.
Using the FIB-4, automatically calculated, followed by the ELF test in second line to screen primary care patients for liver disease
Authors: Ouzan Denis , Penaranda G. , Jlaiel M. , Joly Helene , Corneille Jeremie 
Published: December 2023

Abstract

The objective of our work was to evaluate the screening of hepatic fibrosis in primary care using the FIB-4 score, automatically calculated. When the FIB-4 was ≥ 1.3, it was defined as positive, and ELF Test was performed. FIB-4 positivity was confirmed when ELF Test was ≥ 9.8. Results: Among the 3427 patients included in primary care, 869 (25%) had a positive FIB-4 score, 784 (22.5%) at intermediate (FIB-4: 1.3–2.67), and 85 (2.5%) at high risk of fibrosis (FIB-4 > 2.67). 509 (59%) of the FIB-4 positive were confirmed by the ELF Test. The percentage of confirmation was significantly higher in patients over 65 years (83 vs. 57%), with FIB-4 > 2.67 (80 vs. 56%), BMI > 25 (47 vs. 37%), and diabetes (24 vs. 14%), p = 0.001). In patients without known liver disease (92%), the practitioner identified a cause of disease in 27% of cases: mainly NAFLD and alcohol. Conclusion: Liver fibrosis was suspected on FIB-4 in 25% of patients who consulted a general practitioner. The ELF Test, performed as a second-line, improves the screening of liver fibrosis, particularly for FIB-4 indeterminate results. A positive FIB-4 test allows physicians to recognize a liver disease, providing an opportunity for timely intervention.
Geospatial Discovery of Promising Groundwater Abstraction Zones through Weighted Linear Combination and Probabilistic AHP Approaches
Authors: Dipto Abir Mahmud , Rasel H. M. , Hossain ABM Shafkat , Mamun Abdullah Al , Saki Saleh Ahmad , Ahad S. M. Abdullah Al 
Published: December 2023

Abstract

Global water shortages are getting worse due to the effects resulting from climate change and rising groundwater abstraction. The current study's objective is to evaluate groundwater possibility zones for abstraction (GPZ) in the Dhaka division employing Remote Sensing (RS) and Geographic Information System (GIS) methods. A combination of Linear weight (WLC) along with the Analytical Hierarchy Process (AHP) was employed, integrated with Arc-GIS, to discover Groundwater Possibility Zones for abstraction of a region that spanned from the district's boundaries to 6 kilometers outside. The rate of groundwater abstraction, precipitation, LULC sequence, roughness of the earth's surface, drainage patterning, recuperate stipulation, geomorphology, and the possibility of evapotranspiration (PET) are several variables that affect the area's declining groundwater levels. The settlement area's density of water drainage and penetration region were altered to mitigate the adverse impact on the findings, and seven thematic layers were employed to determine the GPZ for abstraction. The GP estimate found that "shallow" groundwater potential zones covered 6018 km2 (24%) and that "low," "average," "high," and "extremely high" potential zones covered 5143 km2 (19%), 2150 km2, 3138 km2, and 4154 km2 correspondingly. Drainage density was discovered to be the most delicate factor. Based on seven physiographic, geomorphologic, and hydrological characteristics (i.e., precipitation, use of land and vegetation cover, concentration of drainage, contour density, and gradient), both WLC and AHP assessments have been carried out in this instance. The estimated net replenishment quantity for the years 1992 to 2022 was assessed utilizing the concept of the Water Table Fluctuation method.
Navigating daily life with fibromyalgia: Insights from women’s experiences on challenges and coping strategies.
Authors: Sánchez Daniel Sanjuán , Sanz Carolina Climent , Vera Maria del Mar Patiño , Sánchez Montserrat Gea , Carnacea Francesc Rubi , Vozmediano Erica Briones 
Published: December 2023

Abstract

Purpose
Fibromyalgia symptoms can significantly limit a person’s ability to function and participate in daily activities. Exploring patients’ perceptions on the impact of fibromyalgia symptoms on functionality can provide valuable insight on their experiences, coping strategies, needs, and priorities. The aim of this research is to describe the strategies and adaptations used by women with fibromyalgia to carry out basic, instrumental, and advanced activities of daily living.
Methods
Qualitative study based on personal interviews with 25 women diagnosed with fibromyalgia. A thematic analysis was conducted following the classification of activities of daily living into basic (movement and moving around, personal hygiene and getting dressed), instrumental (cleaning, housekeeping, and shopping) and advanced (work).
Results
Participants reported limitations in performing all types of daily activities, including basic (movement and mobility, personal hygiene, dressing), instrumental (cleaning, housekeeping, shopping) and advanced(work-related) activities. To enhance their occupational competence, the identified strategies included energy conservation techniques, balancing activity, and rest, adjusting in the timing and organization of daily activities, delegating tasks, persevering despite pain and fatigue, utilizing technology, and discontinuing certain activities.
Conclusion
Healthcare professionals caring for women with fibromyalgia should recognize the impact of FM on patients’ functionality and employ strategies to improve their adaptation, as well as facilitate the assessment of disability leave.
Demographic predictors of patients’ satisfaction with their recovery after non-catastrophic musculoskeletal injuries: a cross-sectional study
Authors: Maleki Mahshad , Modaressi Shirin , Bakhshi Enayatollah , Hosseini Seyed Ali 
Published: December 2023

Abstract
Background
Orthopedic injuries can significantly negatively influence a patient’s physical and mental health. Achieving patient satisfaction with recovery is essential for reaching patient goals.
Objective
We aimed to investigate whether satisfaction with recovery can be predicted based on demographic information and baseline characteristics in people with non-catastrophic musculoskeletal trauma.
Methods
Participants (n = 100) with acute musculoskeletal injuries were recruited. The Satisfaction and Recovery Index (SRI) was used to assess the patient’s satisfaction with their recovery. A two-tailed Pearson correlation was performed to evaluate the correlation between the SRI scores and continuous variables. One-way ANOVA and independent samples t-test were used to assess whether there were any differences in the SRI scores between ordinal and nominal study variables, respectively. A multivariable linear regression model was created to determine factors independently associated with SRI scores for which all variables with P < 0.10 from the bivariate analysis were included.
Results
There was no association between the SRI scores and age (r = 0.13, P = 0.21), sex (F = 0.94, P = 0.22), educational level (F = 1.07, P = 0.30), number of people living with the patients (r = 0.05, P = 0.60), marital status (F = 0.20, P = 0.87), type of injury (F = 0.53, P = 0.67), injured body part (F = 1.91, P = 0.17), mechanism of injury (F = 0.62, P = 0.60), job(F = 0.47, P = 0.70), time since injury (r = 0.03, P = 0.73).
Conclusions
Demographic variables and baseline characteristics are not associated with the level of satisfaction with recovery among patients with non-catastrophic musculoskeletal trauma. Clinicians can use these findings to rule out these variables as contributors to low (or high) satisfaction with recovery. Future studies must assess the contribution of other probable and relevant psychological and social characteristics.
Genome-wide exploration of metabolic-based pyrethroid resistance mechanism in Helicoverpa armigera
Authors: Kim Juil , Rahman Md-Mafizur , Han Changhee , Jeon Jungwon , Kwon Min , Lee Si Hyeock , Omoto Celso 
Published: December 2023

Abstract

To elucidate the deltamethrin resistance mechanism in Helicoverpa armigera, we explored mutations at the deltamethrin target site, genomic level variations between insecticide-susceptible and -resistant strains, and differences in gene expression patterns between the strains. Known pyrethroid resistance-associated point mutations within the voltage-gated sodium channel were undetected in the cDNA and gDNA of resistant strains or field populations. The whole-genome de novo assembly of a Korean resistant strain was performed (GCA_026262555.1), and 13 genomes of susceptible and resistant individuals were re-sequenced using field populations. Approximately 3,369,837 variants (SNPs and indels) were compared with our reference H. armigera genome, and 1,032,689 variants were identified from open reading frames. A resistance-specific CYP3 subfamily gene with five variants (CYP321A1v1–v5) was identified in the resistant strains, indicating the potential role of these variants in resistance. RNA-seq analysis identified 36,720 transcripts from 45 Illumina RNA-seq datasets of the fat body, gut, and the rest of the body. Differential gene expression analysis revealed some differently overexpressed detoxification enzyme genes in the resistant strains, particularly cytochrome P450 genes. This finding was consistent with the results of bioassay tests using PBO-based synergists, further supporting the role of detoxification enzymes in resistance. Therefore, H. armigera may acquire deltamethrin resistance through a combination of actions, including the overexpression of various detoxification enzymes, such as CYP3 subfamilies (CYP321A5) and cuticular proteins. The five variants of CYP321A subfamily identified in this study may serve as a basis for understanding insecticide resistance at the molecular level and can be applied as diagnostic markers for resistance.