bluuebunny/crossref_metadata_2025_split huggingface dataset:
Adaptive thermal comfort analysis based on interaction between outdoor thermal environment and air pollution: Case study in Xi'an, China
Authors: Zhen Meng , Liu Xiangzi , Liu Xunlei , Bian Guangmeng 
Published: January 2024

Abstract
At present, urban haze pollution is a major problem that affects the outdoor environmental quality, thereby hindering the construction of an ecological civilization and healthy urban development. The urban outdoor thermal environment also influences the urban physical environment. Both the thermal environment and air environment have important effects on the subjective comfort evaluations of people. In this study, four typical spaces on a university campus in Xi'an, China, were selected to investigate the thermal environment and air environment in outdoor spaces. The particulate matter in the air was divided into three different concentrations. The adaptive thermal comfort due to the interaction between the outdoor thermal environment and air pollution was studied based on questionnaires and field measurements, and a strategy was developed for optimizing the thermal comfort of outdoor public space environments. The results showed that the influence of the thermal air quality environment on subjective comfort clearly varied among different spaces. The influence of haze pollution on subjective comfort was greater in high and low temperature environments, but less obvious in a moderate temperature environment. When the PM2.5 particle concentration was greater than 100 µg/m3, the evaluation of respiratory comfort was low in the high temperature environment. The perception of air pollution was less sensitive in the thermal environment in covered road sections. Heat pollution and air pollution will affect human health to varying degrees. People with mental diseases are affected most by the outdoor thermal environment and patients with respiratory diseases are affected most by haze pollution.
Familial risk for depression is associated with reduced physical activity: evidence from wrist-worn actigraphy
Authors: Dell'Acqua Carola , Benvenuti Simone Messerotti , Cellini Nicola , Brush C.J. , Ruggerone Alessandra , Palomba Daniela 
Published: January 2024

Abstract

Depression is characterized by reduced physical activity and sleep-wake cycle disturbances, often considered important features of the disease, aligning with the Sensorimotor Systems and the Arousal and Regulatory Systems of the RDoC, respectively. Wrist-worn actigraphy can be leveraged to show objective sleep-wake and daily activity disturbances. While a few studies have suggested that self-reported reduced physical activity and sleep-wake cycle disturbances might both be linked to depression vulnerability, objective actigraphy-based measures in vulnerable samples remain largely unexplored. Seven-day actigraphy data were collected from 20 (13 F) university students with a higher vulnerability to depression, which was determined by the presence of a family history of the condition but no current symptoms, and 32 (21 F) controls with neither a family history of depression nor current depressive symptoms. Actigraphy data were processed using open-source software (GGIR). Daily physical activity, namely gross motor activity, was quantified as average daily acceleration and time spent on moderate-vigorous physical activity (MVPA). The sleep-wake cycle and circadian rhythms were assessed as total sleep duration per night (in hours), sleep within sleep period time (in hours), sleep efficiency (%), and relative amplitude. Individuals with a familial risk for depression showed reduced daily acceleration and time spent in MVPA relative to the control group, particularly on the weekend during their free time away from scheduled activities. On the other hand, the two groups were comparable in terms of sleep estimates. Taken together, reduced physical activity, but not sleep-wake disturbances, seem to be associated with vulnerability to depression and might be a viable target for identification and prevention efforts.
A Beneficial Levels of 25-hydroxyvitamin D for a Decrease in thyrotropin receptor antibody (TRAB) in Patients with Graves' Disease: A Real-World Study
Authors: Zhang Yongze , Chen Yuxia , Lin Luxi , Shen Ximei , lingning Huang , Zhao Fengying , Yan Sunjie 
Published: January 2024

Abstract

Objective
This study aimed to determine whether a relationship exist between pre-therapy 25-hydroxyvitamin D levels and the remission/negative conversion rates of thyrotropin receptor antibody (TRAB) during treatment in patients with newly diagnosed Graves' disease (GD).
Methods
171 patients were included from the Endocrinology Department of the First Affiliated Hospital of Fujian Medical University in March 2013 to April 2016. Ninety-five patients of them were diagnosed at our hospital but transferred to local hospitals for treatment. Seventy-six patients were followed and treated at our hospital with a median follow-up time of 11.03 (range 6–27) months. Patients were divided into 3 groups according to baseline 25-hydroxyvitamin D levels; <20 ng/mL (31,43.05%), 20–29 ng /mL (20,27.78%), and ≥ 30 ng/mL (20,29.17%). The TRAB remission rate and negative conversion rate was assessed among each group.
Results
There was a higher TSH and lower TRAB titer in the 20–29 ng/mL group at initial diagnosis. Cox regression analysis suggested that 20–29 ng/mL group had significantly higher remission rates [RR; 95% CI: 7.505 (1.401–40.201), 8.975 (2.759–29.196),6.853(2.206–21.285), respectively] and negative conversion rates [RR; 95% CI: 7.835 (1.468–41.804),7.189(1.393–37.092), 8.122(1.621–40.688)] at the 6-, 12-, and 24-month follow-up, respectively .The level of 25-hydroxyvitamin D at the time of initial diagnosis was not associated with the re-normal of free Triiodothyronine(FT3), free thyroxineIndex(FT4) or TSH levels during the follow-up.
Conclusion
Newly diagnosed GD patients with appropriate baseline 25-hydroxyvitamin D levels (20–29 ng/mL) are beneficial for the reduction of TRAB during antithyroid therapy.
A Multi-objective Genetic Algorithm for Unequal Area Facility Layout Problem Considering Safety and Cost
Authors: Koosha Hamidreza , Mirsaeedi Fatemeh , Assadi Mohammad Taghi 
Published: January 2024

Abstract
Facility layout problem is crucial in the design of manufacturing systems across industries due to their significant economic implications and considerable impact on various decision criteria, such as safety considerations in the casting industry. The presence of hazardous equipment like furnaces and melt casting units underscores the necessity of layouts that mitigate safety risks. This study introduces a multi-objective programming model tailored for addressing unequal area layouts, simultaneously optimizing transportation costs and safety risks. The proposed nonlinear model is transformed into a linear equivalent to facilitate solution. To generate the non-dominated Pareto solutions, the NSGA-II algorithm is employed, further fine-tuned by the Taguchi method for parameter optimization. Additionally, Goal Programming is applied to derive a singular solution from the Pareto set. Empirical validation is conducted using real-world data from a casting workshop. The results underscore the model's practicality and effectiveness in a real-world context.
Nonlinear responses study of two beams coupled by multiple nonlinear elements considered cubic stiffness
Authors: Liu Hanlin , zhou rui , Sheng Xi , Xu Fei , Xu Jingmang , Wang Yi 
Published: January 2024

Abstract

Since the inception of nonlinear vibration theory, the majority of research has focused on elastic beams connected to a variety of nonlinear factors. Notwithstanding this, coupling beam systems with nonlinear coupling elements have been the subject of few investigations. In light of the fact that numerous coupling beam systems are typically connected via multiple couplers, this study develops a vibration model for two beams coupled by multiple nonlinear elements exhibiting cubic stiffness. The Lagrange method is utilized to compute the magnitude responses of the beam system. Once the accuracy and consistency of the magnitude responses associated with the beam system have been confirmed, a thorough investigation is conducted into the impact of nonlinear elements on the magnitude responses of two beams joined by multiple nonlinear elements exhibiting cubic stiffness. Nonlinear responses, such as peak jumping, intricate responses, and shifting resonance regions, are determined to be the result of nonlinear elements, according to simulation results. Modulating the parameters of nonlinear elements in a rational manner facilitates the regulation of vibrations across multiple resonance regions of the beam system. Parameter changes of nonlinear elements have a substantial impact on both the vibration states and peak values of magnitude responses for single-frequency vibration excitation in resonance regions. The incorporation of nonlinear components into the coupling beam system enables the regulation of both frequency and single-frequency responses. In the case of low damping, nonlinear vibration control for a system consisting of two beams through the use of multiple nonlinear elements with cubic stiffness is more effective.
Intelligent nonlinear predictive control for wheeled mobile robot on uncertain path
Authors: jalalnezhad mostafa 
Published: January 2024

Abstract

In this paper, the weak points have been investigated, the proposal to solve them, the application of the solution and the comparison of the results in the mode of simulation and experimental testing have been discussed. For this purpose, a four-wheel mobile robot has been considered for simulation and implementation, and a linear quadratic regulator controller and a nonlinear model predictive controller have been used to control it. But the combination of these classic and modern controllers with machine learning can greatly help to make these controllers work more accurately; As a result, in order to increase the accuracy of the performance of these controllers, by training neural networks of multilayer perceptrons, the controllers have been made intelligent. Controllers with cost function have coefficients as weighting to the matrix of system state variables and control input, which are greatly affected by changing these two weighting matrices of problem solving and optimization. For this reason, it is necessary to extract these two matrices for each separate path in order to improve the performance of the controller by trial and error. But by applying the proposed network which is trained with a new algorithm, not only the performance accuracy has increased, but the network extracts these two matrices without the need to spend human energy. Also, in order to reduce the existing time delays, especially in the implementation of the nonlinear controller on the robot in the experimental mode, by training other neural networks to optimally extract the benefit of the forecast horizon, reducing the calculations and increasing the speed of the solution has been achieved. In the hardware part, by examining and using operators such as the pixy camera and the U2D2 interface, which are faster than the usual method, the solution time has been reduced.
Dynamic Monolithic X-ray Imager with Enhanced Performance via Strain Relaxation in Metal-Halide Scintillator
Authors: Zheng Xiaojia , Shu Chongrui , Zhang Caixin , Yuan Ruihan , Liu Xixi , Tie Shujie , Yang Ning , Lian Xuan , Zhu Jianguo 
Published: January 2024

Abstract
Scintillation X-ray detectors have widespread applications in medical imaging, non-destructive testing, and security inspection. In recent years, metal halide materials have gained attention as scintillators due to their superior properties, such as excellent luminescent performance, non-toxicity, and cost-effectiveness etc. Here, we found the lattice strain in Cs5Cu3Cl6I2 can obviously deteriorate its scintillation performance, and the relaxion of lattice strain in Cs5Cu3Cl6I2 largely reduced nonradiative recombination and enhanced its stability. As a result, a high photoluminescence quantum yield (PLQY) of 99.5% was achieved in the strain-released Cs5Cu3Cl6I2 scintillator. We further developed the first monolithic X-ray imaging systems by integrating Cs5Cu3Cl6I2 scintillators with Complementary Metal Oxide Semiconductor (CMOS), which delivered superior imaging clarity with a high-resolution over 30 line-pairs per millimeter (lp mm− 1) and capability of fast dynamic X-ray imaging. Moreover, the Cs5Cu3Cl6I2 monolithic X-ray imaging system shows remarkable stability against heat, humidity, and continuous X-ray irradiation. This research presents a feasible pathway for fabricating monolithic X-ray imagers and highlights their potential for practical applications. We anticipate that our findings will offer new insights into strain engineering of metal halide scintillators and structural design of advanced X-ray imaging systems.
Improving practices in orthogeriatric care services: a multi-method study
Authors: VISADE Fabien , Havet Simon , Robinet Pierre , Maladry François , D'Hulster Quentin , Lerooy Alexandre , Maciejasz Pierre , Rousselet Louis , Preda Cristian 
Published: January 2024

Abstract
Purpose
Orthogeriatric units have proven to be relevant in the care of older patients. A combination of hospital and community care is recommended for optimized care when these older patients return home. However, general practitioners (GPs) have not provided any feedback on this. The aim of this study was to look at GPs’ opinions on the care provided in orthogeriatric units to identify areas for improvement.
Methods
Multi-method study combining one phase comprised of a retrospective analysis of data on older patients hospitalized in an orthogeriatric unit, and another phase analyzing GPs’ answers to a questionnaire. By comparing the results of the two analysis phases we were able to identify areas for improvement.
Results
355 hospital stays were analyzed. The mean age of the older patients was 87 years (SD = 5.8), and patients were predominantly women (n = 292, 82%). The most common surgery performed was femur surgery (n = 240, 68%). Patients suffered from undernutrition (n = 226, 64%), a vitamin D deficiency (n = 247, 70%) and chronic falls (n = 55, 16%). The questionnaire was completed by 51 GPs. Comparing the results of the retrospective analysis and questionnaire identified two areas for improvement: (i) helping patients receive osteoporosis care; (ii) involving occupational therapists more during the orthogeriatric unit stay.
Conclusion
Improvements in practices are always needed, especially when caring for older patients. In orthogeriatric units, this care must involve occupational therapists more and improve screening and treatment for osteoporosis.
Mitigating Natural Risks: Structural Assessment of Urban Trees in Belo Horizonte's Central Region Using Acoustic Tomography
Authors: DE GÓES MATHEUS BARRETO , Michelin Guilherme Antonio , de Oliveira Marina Ferreira Lapa , Carrasco Edgar Vladimiro Mantilla 
Published: January 2024

Abstract
Urban trees play an important role in the quality of life in cities, offering benefits such as shade, improved air quality, and a pleasant environment. This study analyzed urban trees in the central region of Belo Horizonte using an acoustic tomograph to assess their structural safety. The study focused on large trees, which are common in the area. Some trees showed degraded ends, but this did not represent a significant risk to their structural safety. These findings can be used as an argument to preserve the trees in this specific area, countering concerns related to structural safety. The use of acoustic evaluation methods, such as the acoustic tomograph, proved to be an efficient and accessible approach to detect internal defects in living trees. These methods can contribute to safety in public areas and provide quick and reliable results. Although the results of this study indicated that the analyzed trees are in good condition, it is important to consider other aspects related to the preservation of urban trees in order to promote a healthy and sustainable urban environment.
Comparison of Clinical Efficacy of Molecular Targeted Drugs Combined with Transcatheter Arterial Chemoembolization and Transcatheter Arterial Chemoembolization Alone for Primary Liver Cancer
Authors: Sun Xinru , Wang Bojiang , Zhang Yin , Liu Baodong , Sun Liping , Huang Guangming 
Published: January 2024

Abstract
Objective: it was to explore the therapeutic value of transcatheter arterial chemoembolization (TACE) combined with molecular targeted drugs (MTD) in patients with primary liver cancer (PLC).
Methods: 78 patients with PLC hospitalized in Zibo Central Hospital were randomly grouped. Group A was treated with TACE alone, group B with bevacizumab combined with TACE, and group C with sorafenib combined with TACE, 26 cases in each. The patients were followed up for 1 year, and the clinical efficacy, adverse drug reaction (ADR), laboratory indexes, and survival rate (SR) of the three groups were observed and evaluated.
Results: The effective rate and disease control rate of group C were 50% and 69.23%, respectively, which were clearly higher than those of groups A (15.38%, 38.46%) and B (34.61%, 53.84%). There was no obvious distinction in serum Alpha-fetoprotein (AFP) and carcinoembryonic antigen (CEA) levels among them before treatment. Following treatment, group C (404.37±12.47 ng/mL; 246.52±38.17 ng/mL) were clearly lower than those in groups A (483.74±13.28 ng/mL, 367.28±47.03 ng/mL) and B (450.28±12.19 ng/mL, 291.72±43.69 ng/mL). The incidence of ADR in group C was generally lower than that in groups A and B, without obvious distinction in ADR of TACE among them. The overall survival time was obviously longer in group C (11.8 months) than in groups A (8.4) and B (10.1). Following 6 months of treatment, SR was not evidently different among them. Following 12 months of treatment, the SR was obviously superior in group C (84.61%) as against groups A (57.69%) and B (73.07%) (P < 0.05).
Conclusion: TACE combined with MTD is superior to TACE alone in the treatment of PLC. The efficacy, survival time, and SR of sorafenib are better than those of bevacizumab.
Dose-volume predictors of radiation dermatitis in patients undergoing radiotherapy after radical mastectomy for breast cancer
Authors: han ning , zhang yaotian , wu monan , weng chong , dong meiqi , zhang na 
Published: January 2024

Abstract
Purpose
To analyze incidence and dose-volume predictors of acute radiation dermatitis (ARD) in patients with breast cancer who undergo regional nodal irradiation.
Methods and materials:
Patients treated with Intensity-modulated radiation therapy (IMRT) in the chest wall, supraclavicular/subclavicular fossa, secondary axilla, and/or intramammary link after mastectomy were included. The prescribed dose was 50 Gy in 25 fractions. ARD was evaluated and graded once during radiotherapy(RT), 1 week after RT, and at the 1 month follow-up. Grading was performed according to the National Cancer Institute Common Toxicity Criteria for Adverse Events version 3.0. Total skin volume, mean dose, maximum dose, relative volume (RV5-RV45) and absolute volume (AV5-AV45) in patients receiving at least 5 to 45 Gy in 5 Gy increments were assessed. Univariate and multivariate logistic regression analyses were performed to identify risk factors for ARD and to obtain ROC curves. Thresholds for skin dosimetry parameters were determined.
Results
A total of 134 patients with breast cancer who received recruited RT were included in this analysis. Among all patients the incidence of ≥ 2 ARD was 33.58% (45/134), of which the incidence of grade 2 ARD was 32.09% (43/134), and the incidence of grade 3 RD was 1.49% (2/134). No grade 4 or 5 ARD was observed. After univariate and multivariate analyses, age, BMI, BSA, sex, tumor laterality, vascular cancer embolus, nerve invasion, adjuvant chemotherapy were not significantly associated with the risk of grade ≥ 2 ARD. Internal mammary nodal irradiation (IMNI) (P = 0.049) and targeted therapy (P = 0.005) were independent risk factors for ARD. AV35 (P = 0.030) and AV40 (P = 0.025)of the skin were significantly associated with the risk of grade ≥ 2 RD. According to the ROC curves, the optimum thresholds were 199 mL for AV35 and 181.8 mL for AV40, respectively.
Conclusion
The receipt of targeted therapy during radiation therapy and IMNI are risk factors for the development of grade 2 ARD. Maintaining AV35 on the upper skin at < 199 mL and AV40 at < 181.8 mL may decrease the risk of ARD.
Guidewire-Assisted Endoscopic Guidance for Difficult Placement of Nasojejunal Tubes
Authors: Wang Ziwei , Ji Feng 
Published: January 2024

Abstract

Background
Effective nasojejunal tube feeding is valuable for patients at high risk of aspiration who are intolerant to oral or gastric feeding. Placement of nasojejunal tubes is difficult in patients with gastroduodenal obstruction due to inability of endoscopic guidance.
Aims
We report the technique of guidewire-assisted endoscopic guidance for difficult placement of nasojejunal tubes.
Methods
A retrospective study was conducted on 13 patients with gastroduodenal obstruction experiencing difficult nasojejunal placement at a single tertiary care center. The primary outcome was success rates of tube placement. Secondary outcomes included procedure time, complications, symptom remission and nutritional indicators.
Results
The primary outcome showed a 92.31% success rate of placement. The secondary outcome showed a 16.30 ± 7.05 minute average procedure time. There were significantly higher success rates of placement and improved nutritional status. Complication incidence was not significantly increased after placement.
Conclusions
Guidewire-assisted techniques are safe and effective for patients with difficulty in nasojejunal tube placement.