bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development of hybrid 3D printing approach for fabrication of high-strength hydroxyapatite bioscaffold using FDM and DLP techniques
Authors: Cheng Yu-Jui , Wu Tsung-Han , Tseng Yu-Sheng , Chen Wen-Fan 
Published: January 2024

Abstract
This study develops a hybrid 3D printing approach that combines fused deposition modeling (FDM) and digital light processing (DLP) techniques for fabricating bioscaffolds, enabling rapid mass production. The FDM technique fabricates outer molds, while DLP prints struts for creating penetrating channels. By combining these components, hydroxyapatite (HA) bioscaffolds with different channel sizes (600, 800, and 1000 μm) and designed porosities (10%, 12.5%, and 15%) are fabricated using the slurry casting method with centrifugal vacuum defoaming for significant densification. This innovative method produces high-strength bioscaffolds with an overall porosity of 32%–37%, featuring tightly bound HA grains and a layered surface structure, resulting in remarkable cell viability and adhesion, along with minimal degradation rates and superior calcium phosphate deposition. The HA scaffolds show hardness ranging from 1.43 to 1.87 GPa, with increasing compressive strength as the designed porosity and channel size decrease. Compared to human cancellous bone at a similar porosity range of 30%–40%, exhibiting compressive strengths of 13–70 MPa and moduli of 0.8–8 GPa, the HA scaffolds demonstrate robust strengths ranging from 40 to 73 MPa, paired with lower moduli of 0.7–1.23 GPa. These attributes make them well-suited for cancellous bone repair, effectively mitigating issues like stress shielding and bone atrophy.
Preparation and properties of silica fume@polyure-thane urea cement composites
Authors: Feng Chao , Xu Dongdong , Cheng Hao , Yan Peihui , Wan Fei , Yan Wenwen 
Published: January 2024

Abstract
In this study, a new material was synthesized by compounding silica fume and polyurethane urea, which is used to evaculate the vibration reduction performance of concrete. The mechanical and damping properties of silica fume@ polyurethane urea (SF@PUU) reinforced cement paste were investigated. Also, FT-IR, XRD, TG analysis, and SEM are included. The results indicated that SF@PUU leads to the production of high damping ratio cement pastes. The damping capacities of SF@PUU cement composites, where the damping mechanism included internal, external, and multiphase friction within the cement matrix. Additionally, SF@PUU created a constrained-layer damping structure in cement paste to improve the damping properties. The review confirmed that SF@PUU subjected to proper treatments can be as the replacement to cement in concrete or as a damping filler. However, more investigation is required into the dimensional stability and durability of SF@PUU-based concrete.
An Age Study on Adopting Adult Hypertension Standards in Chinese Mature Children and Adolescents
Authors: Wang Xi , Gao Liwang , Wang Xia , Mi Jie 
Published: January 2024

Abstract

OBJECTIVE
To determine age cutoff values for the use of adult hypertension diagnostic criteria in children and adolescents, and to evaluate the consistency and screening effect of the adult criteria with the sex-, age-, and height-specific blood pressure reference (gold standard).

METHODS
A literature review and expert consultation were used to determine age cutoff value. In children above the cutoff age, the China Child and Adolescent Cardiovascular Health Survey was used to compare the consistency and screening effect between the adult criteria and the gold standard, and Beijing Blood Pressure Study was used to evaluate the predictive value of childhood hypertension diagnosed by adult criteria and gold criteria for hypertension and subclinical cardiovascular damage in adulthood.

RESULTS
(i) Adult criteria can be used to evaluate hypertension for children aged 16 and above. (ii) Among adolescents aged 16 and above, the adult standard has lower sensitivity (21.1%) but higher specificity (100.0%) compared with the gold standard, with a consensus rate of over 80.0%. And the predictive ability of the adult standard for subclinical cardiovascular health damage in adulthood is also similar to that of the gold standard.

CONCLUSIONS
Sixteen years can be used as a cutoff point for the adoption of adult hypertension diagnostic criteria in children, and it has a certain degree of simplicity and accuracy.
Rethinking the Mother–Daughter Plot: Female Polyphony in Najat El Hachmi’s Migration Trilogy
Authors: Codina Solà Núria 
Published: January 2024

Abstract
This article traces the various representations of motherhood in the fictional work of the Catalan-Amazigh writer Najat El Hachmi. By using a contrapuntal reading that retrieves the silenced female voices implicitly embedded in the texts, the article underlines the importance of attending to linguistic and narrative polyphony both in narratives of mothering and in texts in which the mother plays a secondary role. This multilingual and feminist approach to Edward Said’s strategy of contrapuntal reading provides new tools to revisit Marianne Hirsch’s conception of the mother–daughter plot, demonstrating that the mother’s voice is not necessarily absent in narratives of daughters, but rather unheard.
Posterior wall ablation by pulsed-field ablation: procedural safety, efficacy, and findings on redo procedures
Authors: Kueffer Thomas , Tanner Hildegard , Madaffari Antonio , Seiler Jens , Haeberlin Andreas , Maurhofer Jens , Noti Fabian , Herrera Claudia , Thalmann Gregor , Kozhuharov Nikola A , Reichlin Tobias , Roten Laurent 
Published: January 2024

Abstract

Aims
The left atrial posterior wall is a potential ablation target in patients with recurrent atrial fibrillation despite durable pulmonary vein isolation or in patients with roof-dependent atrial tachycardia (AT). Pulsed-field ablation (PFA) offers efficient and safe posterior wall ablation (PWA), but available data are scarce.

Methods and results
Consecutive patients undergoing PWA using PFA were included. Posterior wall ablation was performed using a pentaspline PFA catheter and verified by 3D-electroanatomical mapping. Follow-up was performed using 7-day Holter ECGs 3, 6, and 12 months after ablation. Recurrence of any atrial arrhythmia lasting more than 30 s was defined as failure. Lesion durability was assessed during redo procedures. Posterior wall ablation was performed in 215 patients (70% males, median age 70 [IQR 61–75] years, 67% redo procedures) and was successful in all patients (100%) by applying a median of 36 (IQR 32–44) PFA lesions. Severe adverse events were cardiac tamponade and vascular access complication in one patient each (0.9%). Median follow-up was 7.3 (IQR 5.0–11.8) months. One-year arrhythmia-free outcome in Kaplan–Meier analysis was 53%. A redo procedure was performed in 26 patients (12%) after a median of 6.9 (IQR 2.4–11) months and showed durable PWA in 22 patients (85%) with only minor lesion regression. Among four patients with posterior wall reconnection, three (75%) presented with roof-dependent AT.

Conclusion
Posterior wall ablation with this pentaspline PFA catheter can be safely and efficiently performed with a high durability observed during redo procedures. The added value of durable PWA for the treatment of atrial fibrillation remains to be evaluated.
Predictor of anemia among pregnant women attending antenatal clinics at Hiwot Fana Comprehensive Specialized Hospital, Eastern Ethiopia: a case-control study
Authors: Dufera Tadesse , Dheresa Merga , Dingeta Tariku , Legesse Mezgebu , Mesfin Sinetibeb , Balis Bikila , Balcha Tegenu 
Published: January 2024

Abstract

Background
Anemia during pregnancy is a public health problem and is related to negative birth outcomes, especially in developing countries. The main aim of this study was to assess predictors of anemia among pregnant women attending antenatal clinics at Hiwot Fana Comprehensive Specialized University Hospital, Eastern Ethiopia.

Methods
Unmatched case-control study design was employed among 352 individuals. A face-to-face interview was used to gather data, and each pregnant woman's antenatal care follow-up record cards were reviewed in addition to the interview. EpiData version 3.1 and IBM SPSS version 26 was used for data entry and analysis, respectively. Bivariable and multivariable analyses were conducted to identify predictors of anemia, a p-value of &lt;0.05 was considered a statistically significant association.

Result
The common determinants for anemia in pregnant mothers were: rural residency (AOR = 2.25, 95% CI: 1.14–4.8), no formal education (AOR = 4.4, 95% CI: 1.94–9.9), inter-pregnancy interval (AOR = 2.7, 95% CI: 1.24–5.8), and mid-upper arm circumference (AOR = 5.0, 95% CI: 2.0–12.7).

Conclusion
In this study, the identified determinant factors for anemia were: rural residency, maternal educational status, inter-pregnancy-interval, and mid-upper arm circumference. Therefore, providing health education and promotion for pregnant women regarding anemia by focusing on rural residents and counseling to lengthen their birth spacing is an important task. Moreover, counseling on taking iron supplementation as suggested and consuming a diet rich in iron during antenatal care will be recommended.
Deciphering the hidden structures of HH 216 and Pillar IV in M16: results from JWST and HST
Authors: Dewangan L K , Jadhav O R , Maity A K , Bhadari N K , Sharma Saurabh , Padovani M , Baug T , Mayya Y D , Pandey Rakesh 
Published: January 2024

ABSTRACT
To probe the star formation process, we present an observational investigation of the Pillar IV and an ionized knot HH 216 in the Eagle Nebula (M16). Pillar IV is known to host a Class I protostar that drives a bipolar outflow. The outflow has produced the bow shock, HH 216, which is associated with the red-shifted outflow lobe. The JWST near- and mid-infrared images (resolution ∼0${_{.}^{\prime\prime}}$07–0${_{.}^{\prime\prime}}$7) reveal the protostar as a single, isolated object (below 1000 au). The outer boundary of Pillar IV is depicted with the 3.3 $\mu$m Polycyclic aromatic hydrocarbon (PAH) emission. HH 216 is traced with the 4.05 $\mu$m Brα and the radio continuum emission; however, it is undetected with 4.693 $\mu$m H2 emission. HH 216 seems to be associated with both thermal and non-thermal radio emissions. High-resolution images reveal entangled ionized structures (below 3000 au) of HH 216, which appear to be located towards termination shocks. New knots in 4.693 $\mu$m H2 emission are detected and are mainly found on Pillar IV’s northern side. This particular result supports the previously proposed episodic accretion in the powering source of HH 216. One part of the ionized jet (extent ∼0.16 pc) is discovered on the southern side of the driving source. Using the 12CO(J = 1–0), 12CO(J = 3–2), and 13CO(J = 1–0) emission, observational signposts of cloud-cloud collision (or interacting clouds) towards Pillar IV are investigated. Overall, our results suggest that the interaction of molecular cloud components around 23 and 26 km s−1 might have influenced star formation activity in Pillar IV.
Analysis of Differences in Characteristics of High-Risk Endemic Areas for Contracting Japanese Spotted Fever, Tsutsugamushi Disease, and Severe Fever With Thrombocytopenia Syndrome
Authors: Ogawa Takahisa , Tsuzuki Shinya , Ohbe Hiroyuki , Matsui Hiroki , Fushimi Kiyohide , Yasunaga Hideo , Kutsuna Satoshi 
Published: January 2024

Abstract

Background
Tick-borne infections, including tsutsugamushi disease, Japanese spotted fever, and severe fever with thrombocytopenia syndrome (SFTS), are prevalent in East Asia with varying geographic distribution and seasonality. This study aimed to investigate the differences in the characteristics among endemic areas for contracting each infection.

Methods
We conducted an ecologic study in Japan, using data from a nationwide inpatient database and publicly available geospatial data. We identified 4493 patients who were hospitalized for tick-borne infections between July 2010 and March 2021. Mixed-effects modified Poisson regression analysis was used to identify factors associated with a higher risk of contracting each tick-borne disease (Tsutsugamushi, Japanese spotted fever, and SFTS).

Results
Mixed-effects modified Poisson regression analysis revealed that environmental factors, such as temperature, sunlight duration, elevation, precipitation, and vegetation, were associated with the risk of contracting these diseases. Tsutsugamushi disease was positively associated with higher temperatures, farms, and forests, whereas Japanese spotted fever and SFTS were positively associated with higher solar radiation and forests.

Conclusions
Our findings from this ecologic study indicate that different environmental factors play a significant role in the risk of transmission of tick-borne infections. Understanding the differences can aid in identifying high-risk areas and developing public health strategies for infection prevention. Further research is needed to address causal relationships.
An altered expression of miR‐376a‐3p and miR‐20a‐5p in peripheral blood exosomes regulates the autophagy and inflammatory systemic substrates, and relates to the smoking habit and age in Crohn's disease
Authors: Caparrós Esther , García‐Martinez Irma , Pedro Zapater  , Lucía Madero  , Valverde Ángela M. , Ana Gutiérrez  , Francés Rubén 
Published: January 2024

AbstractmiRNAs are short single‐stranded noncoding RNAs that participate as epigenetic regulators in inflammatory bowel disease. Most miRNAs detectable in serum are concentrated in exosomes, with relevant cargo for immunobiological processes. We set to evaluate the exosomes miRNAs content in the serum of patients with Crohn's disease (CD) and run a prospective observational study on CD patients on biological monotherapy and healthy controls. miRNA cargo was evaluated in peripheral blood‐derived exosomes. Serum autophagy and inflammatory substrates were measured. Patients were followed for 6 months. Patients (n = 28) showed an overexpression of miR‐376a‐3p and a downregulation of miR‐20a‐5p compared to controls (n = 10), without significant differences between patients according to biologics. Serum autophagy substrates ATG4C (r = .57; p = .001) and ACRV1C (r = .66; p = .001) inversely correlated with miR‐376a‐3p expression, whereas IGF1R correlated with miR‐20a‐5p expression (r = .42; p = .02). Th1‐related cytokines correlated with miR‐376a‐3p expression, whereas the Th17‐associated cytokines inversely correlated with miR‐20a‐5p expression. Smoking (β = −2.301 CI 95% −3.790/−0.811, p = .004) remained as independent factor related to the overexpression of miR‐376a‐3p, whereas diagnosis before 16 years of age (β = 2.044 CI 95% 0.934/3.154, p = .001) and a younger age of patients (β = −.720 CI 95% −0.108/−0.035, p = .001) were related to decreased miR‐20a‐5p expression. Seven patients (25%) had a flare in the 6‐month follow‐up. Patients with overexpression of miR‐376a‐3p at the baseline showed an increased risk of flare during this period (OR 0.475 [0.237–0.950], p = .035). Finally, a comparative miRNA signature between biologic monotherapies was also explored. Targeting miR‐376a‐3p and miR‐20a‐5p epigenetic regulators may yield homeostatic effects on relevant biological processes related to disease progression in CD patients.
Relationship Between the Clinical Learning Environment and Caring Behaviors Among Baccalaureate Nursing Students During the COVID-19 Pandemic
Authors: Inocian Ergie P. , Kelly Susan H. , Paragas Emmanuel D. , Felicilda-Reynaldo Rhea Faye D. , Turk Melanie T. 
Published: January 2024

Abstract
Caring is a fundamental professional nursing value. This study examined the effect of the clinical learning environment (CLE) on nursing students’ caring behaviors during the COVID-19 pandemic. Valuing nursing work in the CLE increased the knowledge and skills aspect of caring behavior. Higher CLE scores in affordances and engagement and student centeredness increased the respectful deference of others and positive connectedness aspects of caring behaviors. These results may inform efforts to promote aspects of nursing students’ caring behaviors during global health emergencies by enhancing the value of nursing work, engagement, and student-focused qualities of the CLE.
Aesthetic Expression as a Means to Nurture “Self” in a Basic Nursing Care Practicum
Authors: Betriana Feni , Promnoi Chantra , Nilmanat Kittikorn 
Published: January 2024

Abstract
Nursing students develop their professional “self” through clinical placement experiences. Aesthetic expression can be used as a means to reflect students’ personal knowing and to convey self as nurtured during their clinical journey. In a postconference session of the Basic Nursing Care Practicum course, six students were asked to draw pictures reflecting their clinical experience and then share their stories. It appeared that nursing students learned the meaning of nursing and caring, and through these meanings, their actual self as nurses was also developed.
Integrating Experiential Informatics and Quality Improvement in Baccalaureate Education
Authors: Brunel Mallory , Allert Jenny 
Published: January 2024

Abstract
Current education for prelicensure students addresses informatics, typically focusing on theory, terminology, and an overview of systems. This leaves health partners with the burden of teaching “bedside” informatics skills. Utilizing an innovative new model, a course was developed to bridge the gap between theory and practical application. Students join mock clinical practice councils and perform chart audits to understand the important role of informatics in quality improvement. By using practical bedside informatics tools and applications, students learn to improve patient outcomes and safe care environments in alignment with current expectations.
A Qualitative Study of Rehabilitation Professionals' Practices to Define the Presence of Arm Morbidity After Breast Cancer Surgery
Authors: Francisco Beatrice A. , Zadravec Kendra , Edwards Amy N. , Warren Alora , Johnson Katherine A. , Dau Catalina , Rafn Bolette S. , Campbell Kristin L. 
Published: January 2024

Background:Rehabilitation professionals (RPs) play a major role in identifying, managing, and treating upper-body issues in individuals following breast cancer surgery. Varying definitions of postoperative arm morbidity in the literature have hampered development of standardized surveillance programs for people undergoing breast cancer surgery within clinical care. Our objective was to explore RPs' practices in defining the presence of arm morbidity after breast cancer surgery.Methods:This qualitative study used semistructured focus group interviews with 29 RPs from 5 health authorities in British Columbia, Canada. Transcripts were analyzed using content analysis.Results:Two categories captured RPs' overarching lack of consensus in defining the presence of postoperative arm morbidity: (1)Complex concerns, complex considerations; and (2)Many ways of measuring arm morbidity. Varying perspectives exist as to which upper-body issues and functional criteria constitute arm morbidity, as well as which characteristics to consider in identifying who is at risk of developing arm morbidity. In tandem, there is currently no gold standard outcome measure or standardized assessment to identify arm morbidity.Conclusion:Because of the complex interaction between different breast cancer treatments and various environmental and personal factors, there is currently a lack of consensus among RPs about how to define and assess arm morbidity. Our findings demonstrate the presence of arm morbidity is challenging to characterize, given its multifaceted presentation, inconsistent approaches to risk stratification across clinical settings and geographical regions the RPs worked, and numerous ways of measuring arm morbidity.
Naltrexone Compared With Buprenorphine or Methadone in Pregnancy
Authors: Atluru Sreevalli , Bruehlman Alyssa K. , Vaughn Porcia , Schauberger Charles W. , Smid Marcela C. 
Published: January 2024

OBJECTIVE:
Although naltrexone is an evidence-based medication for opioid use disorder (MOUD), few data are available with use in pregnancy. Our objective was to assess outcomes of pregnant individuals with opioid use disorder (OUD) taking naltrexone compared with those taking methadone or buprenorphine.

DATA SOURCES:
We undertook a systematic review using electronic database search (PubMed, CINAHL, EMBASE, PsycInfo), conference proceedings, and trial registries including ClinicalTrials.gov.

METHODS OF STUDY SELECTION:
We conducted an electronic search of research articles through May 2023 for randomized controlled trials, prospective cohort, and retrospective cohort studies of naltrexone (oral, implant, or extended release) compared with methadone or buprenorphine (sublingual or extended release) among pregnant individuals with OUD. After double review of all articles, we abstracted obstetric (primary outcome: gestational age at delivery), neonatal (primary outcome: neonatal abstinence syndrome [NAS]), and substance use outcomes.

TABULATION, INTEGRATION, AND RESULTS:
Five studies met eligibility criteria; four were retrospective cohort studies, and one was a prospective cohort study. Four studies included data on gestational age at delivery (weeks) with no difference detected between the two groups in any study (mean difference ranging −0.20, 95% CI, −1.49–1.09 to 0.8, 95% CI, −0.15 to 1.75). Three studies included data on NAS with all studies detecting a lower risk in the naltrexone group compared with methadone or buprenorphine (relative risk ranging from 0.08, 95% CI, 0.01–1.16 to 0.15, 95% CI, 0.06–0.36). Most studies (four of five) had a moderate or high potential for selection bias primarily driven by small sample size and lack of controlling for confounders.

CONCLUSION:
Although the evidence base is limited, available data suggest that naltrexone use in pregnancy is a reasonable MOUD option with reassuring perinatal outcomes. To enhance confidence in this conclusion and to assess substance use outcomes, further comparative studies of pregnant people with OUD taking naltrexone and other MOUD types are needed.

SYSTEMATIC REVIEW REGISTRATION:
PROSPERO, 42017074249.
Characteristics of Elderly-Onset Rheumatoid Arthritis Patients With COVID-19
Authors: Xiao Lanlan , Ma Xinlei , Wu Jinzhi , Liang Junyu , Chen Weiqian , Lin Jin 
Published: January 2024

Abstract
This study aimed to investigate the clinical characteristics of elderly-onset rheumatoid arthritis (EORA) patients with COVID-19. We retrospectively enrolled EORA patients diagnosed with COVID-19 from December 2022 through February 2023 and followed them up. Demographic characteristics of the patients and clinical data on COVID-19 were collected, and EORA-related data at the onset of rheumatoid arthritis and during COVID-19 episodes were evaluated. A total of 102 EORA outpatients were enrolled and stratified into the COVID-19 group (n = 60) and the non–COVID-19 group (n = 42). In the COVID-19 group, 56 (93.3%) had symptoms, 8 (13.3%) had viral pneumonia, and 4 (6.7%) developed severe COVID-19. Multivariate logistic regression analysis showed that lack of COVID-19 vaccination (P = 0.016 and P = 0.030, respectively) and having interstitial lung disease (P = 0.013 and P = 0.001, respectively) were independent risk factors for viral pneumonia and severe COVID-19. Compared with the general population, EORA patients did not show significantly higher susceptibility to COVID-19 or a higher risk of severe COVID-19. However, EORA patients with interstitial lung disease require special consideration during COVID-19 episodes.