bluuebunny/crossref_metadata_2025_split huggingface dataset:
Calorimetry and structural analysis of uranyl sulfates with rare topologies
Authors: Perry Samuel N. , Kurama Arkin , Martin Maximilian , Burns Peter C. 
Published: January 2024

Abstract
Uranyl sulfate minerals are the most rapidly expanding group of uranium minerals, with dozens of species described in the past decade from the localities of White Canyon, U.S.A. and Jáchymov, Czech Republic. Synthetic analogs of a suite of uranyl sulfate minerals were crystallized, characterized, and the standard-state enthalpies of formation (ΔHfo) were determined. Synthetic lussierite is monoclinic, space group Cc, a = 9.2896, b = 28.685, c = 9.6155 Å, β = 93.504°. Synthetic geschieberite is ortho-rhombic, space group Pna21, a = 13.7408, b = 7.2713, c = 11.5844 Å. The standard-state enthalpies of formation from the binary oxides for lussierite, péligotite, shumwayite, geschieberite, and bluelizardite are –3214 ± 78, –2026 ± 33, –587 ± 22, –966.1 ± 10.9, and –2084 ± 21 kJ/mol, respectively, while the standard-state enthalpies of formation of each phase from its elements are –9743 ± 78, –7220 ± 33, –5255 ± 22, –3916 ± 20, and –7117 ± 21 kJ/mol, respectively. The ΔHfo of péligotite was accurately estimated using the ΔHfo of lussierite, bluelizardite, and literature values of the oxide components of each phase. This implies that estimates can be made accurately of the ΔHfo of uranyl sulfates of minerals without synthetic analogs.
A Differential Protein Study on Bronchoalveolar Lavage Fluid at Different
Stages of Silicosis
Authors: Zhang Xiaoxuan , Han Ke , Kan Linhui , Zhang Zheng , Gong Yihong , Xiao Shuyu , Bai Yuping , Liu Nan , Meng Chunyan , Qi Huisheng , Shen Fuhai 
Published: January 2024

Objectives:
In this study, by comparing the difference in protein expression in bronchoalveolar lavage fluid between silicosis patients in different stages and healthy controls, the
pathogenesis of pneumoconiosis was discussed, and a new idea for the prevention and treatment
of pneumoconiosis was provided.

Methods:
The lung lavage fluid was pretreated by 10 K ultrafiltration tube, Agilent 1100 conventional liquid phase separation, strong cation exchange column (SCX) HPLC pre-separation, and
C18 reverse phase chromatography desalting purification, and protein was labeled with isotope.
GO, KEGG pathway, and PPI analysis of differential proteins were conducted by bioinformatics,
and protein types and corresponding signal pathways were obtained.

Results:
Thermo Q-Exactive mass spectrometry identified 943 proteins. T-test analysis was used
to evaluate the different significance of the results, and the different protein of each group was
obtained by screening with the Ratio≥1.2 or Ratio≤0.83 and P<0.05. We found that there are 16
kinds of protein throughout the process of silicosis. There are different expressions of protein in
stages Ⅲ/control, stages Ⅱ/control, stage Ⅰ/control, stages Ⅲ/ stages Ⅱ, stages Ⅲ/ stage Ⅰ and
stages Ⅱ/ stage Ⅰ groups. The results of ontology enrichment analysis of total differential protein genes show that KEGG pathway enrichment analysis of differential protein suggested that
there were nine pathways related to silicosis.

Conclusion:
The main biological changes in the early stage of silicosis are glycolysis or gluconeogenesis, autoimmunity, carbon metabolism, phagocytosis, etc., and microfibril-associated glycoprotein 4 may be involved in the early stage of silicosis. The main biological changes in the
late stage of silicosis are autoimmunity, intercellular adhesion, etc. Calcium hippocampus binding
protein may participate in the biological changes in the late stage of silicosis. It provides a new
idea to understand the pathogenesis of silicosis and also raises new questions for follow-up research.
The Effectiveness of Perinatal Omega-3 Supplements in Neurodevelopment and Physical Growth of 9- and 12-month-old Infants: A Follow-up of a Clinical Trial
Authors: Sarrafi Somayyeh , Pourzeinali Samira , Shakouri Seyed Kazem , Farshbaf-Khalili Azizeh , Ostadrahimi Alireza 
Published: January 2024

Background:
Omega-3 fatty acids (FAs) are essential long-chain polyunsaturated fatty
acids (LCPUFAs) that are essential for optimal health and development.

Objective:
The present study aimed to evaluate the effectiveness of maternal fish oil (containing
omega-3 LCPUFA) intake from 21th week of pregnancy to 30 days postpartum for neurodevelopment
and growth of infants at 9 and 12 months.

Methods:
This was a follow-up study of a triple-blinded clinical trial. The study population was 9--
month-old infants. Their mothers were randomly divided into two groups of 75 people with a 1:1
ratio to take one fish oil supplement or a placebo daily. The anthropometric indicators of infants at
months 9 and 12 and neurodevelopment at month 12 by the ASQ questionnaire were measured. In
the fish oil and placebo groups, respectively, 73 and 71 infants at nine months, as well as 71 and
69 at 12 months, were analyzed.

Results:
No statistically significant impact was observed following consuming omega-3 capsules
on the neurodevelopmental domains, growth parameters, and the profile of maternal serum FAs (p
> 0.05) except DHA. Neurodevelopmental problems were illustrated in one case in the intervention
group and two cases in the placebo group.

Conclusion:
Perinatal relatively low-dose omega-3 LCPUFAs supplements indicated no statistically
significant impacts on the growth and neurodevelopment of 9- and 12-month-old infants in a
population with low consumption of marine products. Further studies investigating the effect of
higher doses of omega-3 LCPUFAs are suggested.
Diagnostic Value of Short Course Low-dose Prednisolone in Patients with
Clinically Suspected Seronegative Inflammatory Arthritis - A
Retrospective Study
Authors: Shan Sam , Mian Mueed 
Published: January 2024

Objective:
We aim to establish the utility of a trial of low-dose systemic glucocorticoid
therapy in the assessment of new clinically suspected inflammatory arthritis patients.

Methods:
We retrospectively identified patients from a private rheumatology practice in Melbourne,
Australia between January 1st, 2019, and December 31st, 2021, who presented with clinically
suspected inflammatory arthritis and subsequently underwent a trial of low-dose prednisolone
(15 mg daily weaned over three weeks in 5 mg increments). We excluded patients with known autoimmune/
inflammatory disorders or concurrent immunosuppression at presentation. We collected
basic participant demographic details and clinical details of their presentation, glucocorticoid response,
investigations, and treatment.

Results:
We recruited 177 participants with a median age of 52, and 69.5% were female gender.
The median symptom time to presentation was 12 months. Hands were the most affected joint in
63.3% and 85% had bilateral disease. Among the participants, 29.4% had synovitis on clinical review
and 75.7% had imaging performed as part of the initial assessment. At presentation, the median
CRP was 11 and the median ESR was 16. 79.7% of the cohort experienced significant improvement
in their arthritis symptoms from low-dose glucocorticoids and 83.6% of the cohort required
long-term immunosuppression for an underlying inflammatory condition. Of those who responded
to glucocorticoids, 92.1% were diagnosed with an inflammatory condition. Rheumatoid
arthritis was the most common overall diagnosis in 28%.

Conclusion:
An initial trial of low-dose glucocorticoids in undifferentiated arthritis patients is useful
in predicting the diagnosis of inflammatory arthritis. It is also a predictor of further long-term
steroid-sparing therapy
Chikungunya Arthritis Treatment with Methotrexate and
Dexamethasone: A Randomized, Double-blind, Placebo-controlled Trial
Authors: Amaral José Kennedy , Lucena Gabriela , Schoen Robert Taylor 
Published: January 2024

Background:
Chikungunya fever is a reemerging epidemic disease caused by a single-stranded
RNA alphavirus transmitted throughout by Aedes mosquitoes. Chikungunya virus infection
is a biphasic disease in which 72% to 95% of affected individuals manifest acute chikungunya
fever. Following the acute phase, more than 40% of affected individuals develop arthritis, often
lasting more than 3 months, referred to as chronic chikungunya arthritis, which frequently mimics
rheumatoid arthritis.

Objective:
This study aimed to evaluate the efficacy and safety of treatment of chronic chikungunya
arthritis with methotrexate and dexamethasone in a randomized, double-blind, placebo-controlled
clinical trial.

Methods:
The patients were reassessed for treatment response by the DAS28-ESR, tender joint
count and swollen joint count, Patient Global Assessment, and for secondary measures, including
the Health Assessment Questionnaire Disability Index and Pain Visual Analog Scale.

Results:
Thirty-one subjects were randomized (placebo, n = 16; methotrexate, n = 15); 27 completed
treatment and 4 discontinued during the 8-week blinded period. Among the participants, 96.8%
were female, with mean ± SD age was 52.9 ± 13. The mean ± SD disease duration prior to treatment
was 220.9 ± 51.2 days. At 8 weeks, methotrexate-treated subjects showed a greater numerical
trend towards improvement, but there were no significant differences between methotrexate-
dexamethasone group and dexamethasone (placebo) group

Conclusion:
In this relatively small cohort, all of whom received background dexamethasone,
there was a greater numerical improvement trend in prespecified outcome measures, but
methotrexate in combination with dexamethasone was not superior to dexamethasone in chronic
chikungunya arthritis.
Chest CT Radiomics is Feasible in Evaluating Muscle Change in Diabetes
Patients
Authors: Li Ting , Wu Gang 
Published: January 2024

Background::
Non-invasive imaging methods are still lacking for the evaluation of muscle changes in diabetes.

Purpose::
To investigate the feasibility of muscle CT radiomics in evaluating muscle changes in diabetes.

Materials and Methods::
60 diabetics and 60 health controls (HC) were assessed with the method of muscle CT radiomics. 93 CT images of radiomics features of the
pectoralis major muscle (PMM) were obtained by using the software 3D Slicer and were then compared between diabetics and HC cases. The least
absolute shrinkage and selection operator (LASSO) regression method was used to establish a prediction model. The receiver operating
characteristic (ROC) curve was used to determine the performance of the model.

Results::
Diabetics and HC cases differed in 19 radiomics features (P<0.05). By using the LASSO method, 6 features were finally selected. The AUC of the
model in the discrimination of diabetics and HC were 0.92 and 0.90, respectively, for the training cohort and validation cohort.

Conclusion::
Muscle CT radiomics is feasible in evaluating muscle changes in diabetes.
Diagnostic Efficacy of High-frequency Ultrasound (HFU) in Early Diagnosis of
Congenital Hip Dysplasia
Authors: Gu Ran , Yuan Liang , Guan Zhiye , Lin Yudong , Zhang Sicheng , Sun Jun 
Published: January 2024

Background::
Hip dysplasia is one of the most prevalent disorders in children and one of the three primary congenital orthopedic deformities. Although there are
numerous existing methods (e.g., CT, MRI and arthrography) for early identification of hip dysplasia, their diagnostic criteria differ widely. It is
critical to establish a safe, accurate, and reliable way for early diagnosis and treatment of hip dysplasia.

Objective::
This study aimed to analyze the diagnostic efficacy of high-frequency ultrasound (HFU) for congenital developmental hip dysplasia and hip
dislocation and to provide a reference for the early diagnosis of congenital hip dysplasia in the future.

Methods::
A total of 104 infants and children suspected of having congenital hip dislocation or developmental hip dysplasia admitted to our hospital from
April 2019 to August 2022 were enrolled as study subjects. All the infants and children were subjected to HFU and X-ray examination in our
hospital. The diagnostic efficacy of HFU for congenital hip dysplasia was observed using X-ray as the gold standard.

Results::
HFU confirmed 79 cases of congenital hip dysplasia, while X-ray confirmed 71 cases. The sensitivity and specificity of HFU were 77.42% and
83.33%, respectively, in the diagnosis of congenital developmental hip dysplasia, 76.47% and 96.55% in the diagnosis of congenital hip
dislocation, and 77.22% and 60% in the diagnosis of congenital hip abnormality, which is very close to the gold standard. According to statistics
on infants and children, the majority of patients were girls, and the left joint was more likely to be affected.

Conclusion::
HFU has excellent diagnostic efficiency for congenital developmental hip dysplasia and hip dislocation, which can be considered an early
assessment method for congenital hip dysplasia in the future.
Identify Diabetes-related Targets based on ForgeNet_GPC
Authors: Yang Bin , Wang Linlin , Bao Wenzheng 
Published: January 2024

Background:
Research on potential therapeutic targets and new mechanisms of action
can greatly improve the efficiency of new drug development.

Aims:
Polygenic genetic diseases, such as diabetes, are caused by the interaction of multiple
gene loci and environmental factors.

Objective:
In this study, a disease target identification algorithm based on protein recognition is
proposed.

Materials and Methods:
In this method, the related and unrelated targets are collected from literature
databases for treating diabetes. The transcribed proteins corresponding to each target are
queried in order to construct a protein dataset. Six protein feature extraction algorithms (AAC,
CKSAAGP, DDE, DPC, GAAP, and TPC) are utilized to obtain the feature vectors of each protein,
which are merged into the full feature vectors.

Results:
A novel classifier (forgeNet_GPC) based on forgeNet and Gaussian process classifier
(GPC) is proposed to classify the proteins.

Conclusion:
In forgeNet_GPC, forgeNet is utilized to select the important features, and GPC is
utilized to solve the classification problem. The experimental results reveal that forgeNet_GPC
performs better than 22 classifiers in terms of ROC-AUC, PR-AUC, MCC, Youden Index, and
Kappa.
Pro-oxidant Effects of Repeatedly Heated Sunflower Oil and the Possible
Ameliorative Potential of Elaeodendron transvaalense Leaf Powder in
Sprague Dawley Rats
Authors: Kwape Tebogo Elvis , Masisi Kabo , Kelaotswe Laone , Bati Keagile , Baeti Phazha 
Published: January 2024

Background::
Repeated heating of cooking oils induces the overproduction of reactive
oxygen species with an overwhelmed cellular antioxidant defense system, resulting in oxidative
stress, the known cause of cardiovascular diseases. Elaeodendron transvaalense is a medicinal
plant believed to have phytochemicals that help ameliorate the effects of oxidative stress.

Objective::
This study investigated the pro-oxidant effects of repeatedly heated sunflower oil and
the possible ameliorative potential of Elaeodendron transvaalense leaf powder in Sprague Dawley
rats.

Methods::
Four groups of male Sprague Dawley rats were fed for 4-weeks a standard diet supplemented
without (a) control or with (b) 15% (w/w) repeatedly heated sunflower oil (RHSO),
(c) 15% (w/w) non-heated sunflower oil, (d) 15% (w/w) RHSO and 1.5% ETLP.

Results::
Endogenous antioxidants: Catalase and SOD activities were observed to rise significantly
(p <0.05) in Group 2 when compared to Group 1 and Group 3 respectively. A significant
decline in the SOD and catalase activities was observed in group 4 fed RHSO + ETLP. No significant
differences were observed in the body, liver, and kidney weights of Group 2 when compared
with Groups 1, 3 and 4 respectively, and no significant differences were observed when
comparing Group 4 to Groups 1, 2 and 3. The levels of Lipid profiles; Low-density Lipoproteins
(LDL), Total cholesterol (TC), and Triglycerides (TG) were observed to rise significantly (p
<0.05) in Group 2 when compared to Group 1 and 3, while their significant (p <0.05) decline
was observed in Group 4 fed with RHSO + ETLP. The levels of HDL showed no significant difference
across all groups because the p-values for the difference between groups exceeded the
null hypothesis (p <0.05).

Conclusion::
The findings of this experiment indicate the possible ameliorative potential of
ETLP observed in the significantly (p <0.05) reduced SOD and catalase activities. A significant
(p <0.05) decline in the TC, TG, and LDL to desirable levels further indicated the ameliorative
effects.
Design and Simulation of Multi Unmanned Boat Cooperative Obstacle
Avoidance System Based on 5G Edge Computing
Authors: Rao Yinhui , Chen Yuanming , Hong Xiaobin , Lin Xiaodong 
Published: January 2024

Background::
Compared to single unmanned boat, multi unmanned boats have more flexible mobility and efficient task completion capabilities, which can effectively expand the types of tasks. However, the traditional independent path planning and obstacle avoidance methods of unmanned boats are difficult to meet the requirements of collaborative operation among multiple unmanned boats due to the lack of information exchange.

Objective::
According to the actual demand of multi unmanned boats' cooperative operation, a
method of multi unmanned boats cooperative obstacle avoidance based on 5G edge computing is
proposed to realize the unified planning and scheduling of multi unmanned boats.

Methods::
Firstly, 5G technology and Kubeedge edge computing tools are used to build a multi
unmanned boat collaborative obstacle avoidance system based on cloud, edge and end collaboration,
and the Kubeedge edge computing platform was optimized by optimizing communication
strategies, building a highly available Kubeedge cluster, building a Harbor image center, and using
Web management interfaces further to improve the reliability and stability of the system. Secondly,
the YOLOR-Deepport multi-target recognition and tracking algorithm based on cloud,
edge and end collaborative network is used to complete the recognition and tracking tasks of obstacle
targets, and a set of EECBS path planning methods based on the Kubedge centralized control
platform is designed to plan collision-free and efficient paths for each unmanned boat in realtime.
Finally, the effectiveness of the system was verified through simulation experiments.

Results::
The experimental results show that compared to the traditional autonomous planning obstacle
avoidance method for unmanned boats, the collaborative planning obstacle avoidance
method proposed in this paper can exhibit excellent performance in dense and narrow scenarios,
with a more reasonable navigation path, a range reduction of 20% - 50%, and higher safety.

Conclusion::
The results show that the cooperative obstacle avoidance system based on 5G edge
computing designed in the paper is feasible, and it can effectively realize the cooperative path
planning and obstacle avoidance of multi unmanned boats.
Exploring the Link between Autistic Traits, Emotional
Intelligence, and Self-efficacy in Understanding Social Anhedonia
Authors: Barahmand Usha , Carvey Kefira , Shamsina Naila , Ancheta Angelica Mae , Sanchez Oscar 
Published: January 2024

Abstract:
Autism severity has been found to be associated with social anhedonia.
However, the mechanisms linking the two have not been clarified.

Objective:
The study was designed to examine the link between autistic traits and social
anhedonia. The present study tested a serial mediation model, in which it was hypothesized
that emotional intelligence and self-efficacy were serial mediators of the relationship between
autistic traits and social anhedonia.

Methods:
Data from 245 participants (57.4% females, n = 134) ranging in age from 18 to
65 years were collected through self-report. Participants completed an online composite
questionnaire consisting of The Comprehensive Autistic Trait Inventory, the Wong and
Law Emotional Intelligence Scale, The General Self-Efficacy Scale and the Revised Social
Anhedonia Scale.

Results:
The relationship between autistic traits and social anhedonia was mediated by
emotional intelligence and serially mediated by emotional intelligence and self-efficacy.
Self-efficacy alone failed to link autistic traits to social anhedonia.

Conclusion:
The study provides evidence for the significant role of emotional intelligence
and self-efficacy as mechanisms underlying the relationship between autistic traits and
social anhedonia. The findings are discussed in terms of elucidating the processes through
which autistic traits may confer vulnerability to compromised emotional intelligence and
self-efficacy, which then serve as additional risk factors for social anhedonia.
A comprehensive and detailed review on Mercury Toxicity
Authors: Manpreetkaur K. Gaur  , Kalpana R. Chavhan  
Published: January 2024

Introduction: Mercury is a chemical element with the symbol Hg and atomic number 80. It is also known as quicksilver and was formerly named hydrargyrum. In Ayurveda, use of Mercury in Rasa-Aushadhis has been known to all of us since the era of Nagarjuna who experimented with mercury with intention to eliminate poverty from world. With proper use of mercury in medicinal formulations diseases can be cured but their improper use can lead to various diseases such as Nasabhanga, Mukhroga, Pakshaghat, Twacha Vaivarnya, Unmad and other psychic disorders and can lead to Toxicity. Mercury is an Irritant Inorganic Metal Poison. Metallic mercury is not poisonous when taken by mouth. Poisoning occurs if the finely divided particles or vaporized mercury is swallowed, inhaled or rubbed on the skin. Material & Methods: Various Samhita Granthas, Articles, Textbooks related to Mercury Toxicity were studied. Results & Conclusion: Wide use of Mercury in Ayurvedic & Siddha medicines is evident since many years. As mercury gets deposited in tissues, it can lead to toxicity as a chronic effect. Also, occupational exposure by means of inhalation of vapors can cause many symptoms such as conjunctivitis, stomatitis, cough, dyspnoea, etc. Case studies also reported how Mercury toxicity can affect CVS, Respiratory & CNS systems. PM Appearances, Medicolegal aspect, Treatment, of Mercury Toxicity and Ayurvedic description were discussed.
Identifikasi Risiko Kegagalan Proses Produksi Ipam Karangpilang II Menggunakan Metode Failure Mode and Effect Analysis
Authors: Firsta Endah  , Emma Yuliani  , Tri Budi Prayogo  
Published: January 2024

PDAM Surya Sembada merupakan BUMD yang bekerja pada bidang distribusi air bersih dengan memanfaatkan Sungai Surabaya menjadi salah satu sumber air bakunya. IPAM Karangpilang II telah mengalami peningkatan kapasitas dua kali, dengan kapasitas terakhir sebesar 2.750 liter/detik. Adakalanya dapat terjadi kendala atau kegagalan pada proses produksinya. Studi ini menggunakan metode Failure Mode and Effect Analysis (FMEA) untuk mengidentifikasi risiko kegagalan pada IPAM Karangpilang II. FMEA merupakan metode sistematis untuk mengetahui dan mencegah sebanyak mungkin failure mode. Pendekatan risiko yang dilakukan pada metode ini yakni dengan severity, occurrence, dan detection. Nilai-nilai kegagalan tersebut kemudian digunakan untuk mendapatkan nilai Risk Priority Number (RPN). Hasil RPN merupakan perhitungan matematis dari analisa yang telah dilakukan, yaitu hasil dari severity × occurrence × detection. Berdasarkan analisis menggunakan FMEA diperoleh nilai RPN yang tertinggi pada unit clearator yang terjadi pada gradient kecepatan, kecepatan aliran, dan bilangan reynold. Dimana masing-masing potensi memiliki nilai RPN sebesar 80. Perbaikan yang diusulkan yaitu dengan melakukan pengaturan dan pengecekan debit yang masuk secara berkala menggunakan alat flowmeter atau alat pengukur debit pada inlet bak.