bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single Sensor Compressive Ultrasound Imaging: A Study of Affecting Factors
Authors: Pasyar Pezhman , Makkiabadi Bahador , Montazeriani Zahra , Amoli Ehsan Roodgar 
Published: October 2023

Abstract
Compressed sensing has enabled 2D and 3D ultrasound imaging using a single transducer by encoding lateral and elevation spatial information as temporal variations in the transmitted and received ultrasound signal through a coded aperture in the form of a pseudo-random delay mask. This technology has become increasingly important with the development of ultrasound techniques as it allows for a reduction in machinery size and power consumption. In this article, we develop a model for compressive ultrasound imaging using a single coded sensor to investigate the factors that affect image quality and enable computationally-efficient simulation of the system. We provide a step-by-step guide to creating synthetic data and demonstrate compressive ultrasound experiments of scenes with varying levels of sparseness generated according to a linear image formation model. We then calculate qualitative and quantitative measurements and solve the inverse problem using several sparse recovery solutions to achieve faithful reconstruction of the scene under different signal-to-noise ratios (SNR) and coded sensor geometries. Our model analysis reveals that failure to consider preferable conditions results in degraded peak signal-to-noise ratio (PSNR), mean squared error (MSE), and structural similarity (SSIM) indexes related to the quality of the reconstruction.
Unraveling the Controversy: Transarterial Chemoembolization versus Radiofrequency Ablation in Early Hepatocellular Carcinoma - A Systematic Review and Meta-Analysis
Authors: Abdelgalil Mahmoud Shaban , Elfakharany Bahaa , El-Samahy Mohamed , lkhawaldeh Ibraheem M. , Refaey Neveen , ALsaad Saad Ashraf , Alaraby Dina , Abd-ElGawad Mohamed 
Published: October 2023

Abstract
Background
Patients with hepatocellular carcinoma (HCC) may face challenges when undergoing radiofrequency ablation (RFA) if their tumors are located near critical liver regions, bile ducts, bowel lumen, or diaphragm due to increased risk of complications. In these cases, liver resection or transplantation is not possible; therefore, transarterial chemoembolization (TACE) can be an alternative treatment for early HCC patients. Our study aims to compare the efficacy and safety of TACE versus RFA.
Methods
We collected data from different sources, including Cochrane Library, PubMed, Scopus, and Web of Science. Our inclusion criteria were patients with a single tumor less than 5 cm or three tumors, each less than or equal to 3 cm in size, without spread or invasion. The review examined various factors such as overall survival (OS), recurrence-free survival rate (RFS), progression-free survival (PFS), tumor response (TR), and adverse event rate (AER).
Results
Eighteen studies, involving 4,537 patients were reviewed. Pooled analysis revealed that RFA had better three-year and five-year OS rates compared to TACE (RR = 0.85, 95% CI [0.78, 0.92], p < 0.00001; RR = 0.80, 95% CI [0.73, 0.89], p < 0.0001, respectively). However, for one-year OS, no significant difference was observed, except in specific subgroups (patients aged ≥ 60 years, AFP ≥ 100 ng/ml, or received Adriamycin), where RFA showed better outcomes (RR = 1.02, 95% CI [0.99, 1.05], p = 0.29). Propensity score-matching analyses also demonstrated better three-year and five-year OS rates for RFA (RR = 0.91, 95% CI [0.85, 0.96], p = 0.001; RR = 0.85, 95% CI [0.79, 0.92], p < 0.001, respectively).
Differences in Nutritional Status and Level of Physical Activity Among Adolescents Living in Urban and Rural Areas of Montenegro - National Study
Authors: Vrevic Erol , Malovic Pavle , Bacovic Dragan , Bojanic Danilo , Muratovic Aldijana 
Published: October 2023

Abstract
Background and objectives
Nutritional status and physical activity are important factors for adolescent health. These factors may vary by the type of settlement. Hence, this study aims to assess the nutritional status and physical activity levels, as well as their variations by the type of settlement.
Method
The sample consisted of 1503 adolescents (46.3% male; 53.7% female), with a mean age of 15.7 ± 0.7 years. Nutritional status was assessed using Body Mass Index (BMI), Waist-to-Height Ratio (WHtR), and Body Fat Percentage (BF). Physical activity levels were assessed using the PAQ-C questionnaire. Differences in nutritional status by the type of settlement were analyzed using Chi-square test (p ≤ 0.05), while differences in physical activity levels were analyzed using independent samples t-test (p ≤ 0.05).
Results
In terms of BMI, 14.7% of males were overweight and 10.1% were obese, while 12% of female adolescents were overweight and 3.1% were obese. There were no differences in nutritional status by settlement type (BMI, WHtR, BF). Male adolescents in rural areas had significantly higher physical activity levels compared to urban areas (p = 0.032). They showed higher activity scores during a spare time (p = 0.002), physical education classes (p = 0.002), little breaks (p = 0.007), and lunchtime (p = 0.034). Female adolescents showed significance only in spare time activity (p = 0.020).
Conclusion
The prevalence of overweight and obesity has increased in Montenegro in recent years, with no differences observed by settlement type. However, male adolescents living in urban areas showed lower levels of physical activity compared to their counterparts in rural areas. Strategies should be implemented to promote physical activity among adolescents in urban areas, considering its overall importance.
WITHDRAWN: Spectral and non-spectral property of self-affine measures on ℝn
Authors: Wei-jie Wang 
Published: October 2023

Abstract
In this paper, we study twofold questions regarding the spectrality and non-spectrality of the self-affine measure $\mu_{M,\mathcal{D}}$. Our result characterizes a necessary and sufficient condition on the spectrality of $\mu_{M,\mathcal{D}}$ generated by a generalized symmetric expanding integer matrix $M\in M_{n}(\mathbb{Z})$ and a non-consecutive collinear digit set $\mathcal{D}$.
For the lower triangular expanding integer matrix $M\in M_{n}(\mathbb{Z} )$ and $\mathcal{D}\subset \mathbb{Z}^{n}$, let $\mathcal{Z}_{\mathcal{D}}^{n}:=\{x\in [0,1)^{n} : m_{\mathcal{D}}(x)=0\}$ and $N_{m}^{n}=\{(\bm{r}, \bm{q})\in \mathbb{R}^{n}:\bm{r}:=(r_1,r_2,\ldots,r_{n-m})^{t}\in [0,1)^{n-m}, \bm{q}\in \mathbb{Q}^{m}\setminus \{\bm{0}\} \}$. Denote $p_{m,\mathcal{D}}$ as the positive integers which are determined by $m$ and $\mathcal{D}$ for any integer $m\geq 1$. We show that if $\gcd(\det(M), p_{m,\mathcal{D}})=1$ for $m\geq 1$ and $\emptyset\neq \mathcal{Z}_{\mathcal{D}}^{n}\subset N_{m}^{n}$, then there are at most $(p_{m,\mathcal{D}})^{m}$ mutually orthogonal exponential functions in $L^{2}(\mu_{M,D})$.
BMAL1 deletion protects against obesity and non-alcoholic fatty liver disease induced by a high-fat diet
Authors: Shen Qiwei , Zhan Chongwen , Chen Haoran , Shao Yikai , Xu Bo , Hua Rong , Yao Qiyuan , Liu Wenjuan 
Published: October 2023

Abstract
Background and Aims: Obesity and non-alcoholic fatty liver disease (NAFLD) are major health concerns. The circadian rhythm is an autonomous and intrinsic timekeeping system closely associated with energy metabolism and obesity. Thus, this study explored the role of brain and muscle aryl hydrocarbon receptor nuclear translocator-like1 (BMAL1), a circadian clock regulator, in the development of obesity and NAFLD.Methods We generated BMAL1 knockout (BMAL1 KO) mice to imitate circadian rhythm disruption. The study comprised three groups from the same litter: BMAL1 KO mice fed a high-fat diet (to establish obesity and NAFLD phenotypes), wild-type mice fed normal chow, and wild-type mice fed a high-fat diet. The metabolic and NAFLD phenotypes were assessed via physiological measurements and histological examinations. Quantitative polymerase chain reaction and western blotting were used to identify and validate changes in the signaling pathways responsible for the altered NAFLD phenotypes in the wild-type and BMAL1 KO mice.Results BMAL1 depletion protected against obesity and metabolic disorders induced by a high-fat diet. BMAL1 deficiency also relieved hepatic steatosis and decreased cluster of differentiation 36 and peroxisome proliferator-activated receptor gamma (i.e., PPARγ) expression.Conclusion BMAL1 plays an important role in the development of obesity and NAFLD and, thus, is a potential therapeutic target for these conditions.
Effect of reductive soil disinfestation on soil properties and microbial communities of ginseng cultivated soils, and assessment of its sterilizing effect
Authors: Li Qiong , Wang Ergang , Zhou Yi , Miao Xinyue , Zhan Yu , He Guixiang , Lv Pengyuan , Wang LIxiang , Zhang Tao , Chen Changbao 
Published: October 2023

Abstract
Aims
Reductive soil disinfestation (RSD) has been shown to restructure soil microbial communities and suppress soil-borne diseases. However, the effect of RSD on the chemical and microbial properties of ginseng cultivated soils has been little studied.
Methods
Ginseng cultivated soils in the ginseng genuine medicinal material producing area of China were used for field experiments using RSD with corn stover and bean dregs as substrates. RSD-treated soil chemical and microbial properties were evaluated using chemical analysis and high-throughput sequencing techniques.
Results
RSD significantly changed soil chemical properties as well as soil microbial community composition and structure and decreased the relative abundance of the pathogenic Fusarium genus. Moreover, the efficacy of RSD treatment based on different substrates varied widely, and RSD with bean dregs as substrate had a greater effect on microbial communities and a stronger sterilizing effect. In the next transplanting experiments, ginseng in the RSD-treated soil grew in better condition and with lower incidence and severity of disease.
conclusion
Our study highlights the potential of RSD as an effective method for soil amendment of ginseng cultivation. Its effects on nutrient and material cycling in ginseng cultivated soils need further exploration.
Ensemble of Plug-in Modules for Knee Osteoarthritis Severity Classification Using Radiographs
Authors: Lee Do Weon , Song DaeSeok , Han Hyuk-Soo , Ro Du Hyun 
Published: October 2023

Abstract
Fine-grained classification deals with data with a large degree of similarity such as cat or bird species and similarly, knee osteoarthritis (KOA) severity classification (Kellgren-Lawrence grading) is one of the fine-grained classification tasks. Recently, plug-in module (PIM) that can be integrated to CNN-based or Transformer-based networks has been proposed to provide strongly discriminative regions for fine-grained classification and the results have outperformed the previous deep learning (DL) models. Therefore, a DL model that classifies KOA severity of a knee radiograph was developed utilizing PIMs. The dataset used for the study was a combination of two different open source datasets, Osteoarthritis Initiative and Multicenter Osteoarthritis Study (test set size: 13038). The final DL model was an ensemble of four different PIMs that used Swin and EfficientNet as the backbones (two each). The overall accuracy of the model was 82.252%, the lowest for KL grade 1 (65%) and the highest for KL grade 0 & 4 (90%). An ensemble of PIMs could classify KOA severity using simple radiographs with a fine accuracy, better than most of the previously proposed CNN-based models.
A multi-center cross-sectional study of Chinese Herbal Medicine-Drug adverse reactions using active surveillance in Singapore’s Traditional Chinese Medicine clinics.
Authors: Ng Chester Yan Jie , Zhao Yan , Wang Ning , Chia Kwan Leung , Teo Chun Huat , Peh William , Yeo Pansy , Zhong Linda L.D. 
Published: October 2023

Abstract
Background
This study aimed to investigate the rates and causality of patient-reported adverse events (AEs) associated with concomitant Chinese Herbal Medicine (CHM) and Western Medicine prescription drug (WMPD) consumption through active surveillance in Singapore’s Traditional Chinese Medicine (TCM) clinics.
Methods
A cross-sectional study was conducted at five TCM clinics across Singapore from 8th May till 8th July 2023. Patients were screened to determine rates of CHM and WMPD consumption, and then interviewed if an AE was reported. An expert committee assessed the AE reports to determine causality. Along with descriptive statistics, odds ratios were calculated to determine AE occurrence likelihoods for patients who consumed both CHM and WMPD compared to CHM consumption alone.
Results
1028 patients were screened and 62.65% of them reported concurrent CHM-WMPD consumption. Patients who consumed CHM and WMPD were 3.65 times more likely to experience an AE as compared to CHM consumption alone. 18 AE reports were adjudicated, with most AEs deemed unlikely due to CHM consumption.
Conclusions
A large proportion of patients consumed CHM and WMPD concurrently, thus increasing their risk of experiencing AEs compared to those consuming CHM only. Active surveillance is feasible for detecting AEs, collecting data for causality assessment, and analysis.
Body mass index is associated with health-related quality of life and disease characteristics in young adults with juvenile idiopathic arthritis
Authors: Tuomi Anna-Kaisa , Rebane Katariina , Arnstad Ellen Dalen , Berntson Lillemor , Fasth Anders , Glerup Mia , Herlin Troels , Kautiainen Hannu , Nordal Ellen , Peltomiemi Suvi , Rygg Marite , Rypdal Veronika , Zak Marek , Aalto Kristiina 
Published: October 2023

Abstract
Background
There is a growing interest concerning the relationship between obesity and several medical conditions and inflammation. Nevertheless, there is a lack of studies regarding body mass index (BMI) among patients with juvenile idiopathic arthritis (JIA). Our aim was to investigate the impact of BMI on health-related quality of life (HRQoL) measured with a 36-Item Short Form Survey (SF-36), disease activity, and functional ability in young adults with JIA.
Methods
This study is a part of the population-based Nordic JIA cohort study. Three hundred fifty-five patients from the original study cohort were enrolled in this study. Patients were classified according to the World Health Organization (WHO) into four groups based on their BMI. HRQoL, disease characteristics, functional ability, fatigue, sleep quality, physical activity, pain, comorbidities, and social status were assessed.
Results
A significant relationship was found between the JIA categories and BMI groups (p = 0.014). A significant relationship was also found between BMI and disease activity scores (DAS28) (p = 0.028), functional ability (p < 0.001), pain (p = 0.013), fatigue (p = 0.035), and sleep quality (p = 0.044). Moreover, a significant relationship between BMI and HRQoL regarding bodily pain (p = 0.010) and general health (p = 0.048) was revealed when adjusted for sex, age, and JIA subtype.
Conclusion
We discovered that BMI was significantly related to HRQoL, disease activity, and disability. BMI deserves more attention considering the treatment options and outcome of JIA in young adults.
Nanoparticle Vaccines Based on the Receptor Binding Domain (RBD) of Porcine deltacoronavirus (PDCoV) Elicit Robust Protective Immune Responses in mice
Authors: Wang Yuanhong , Song Junhan , Wang Junna , zhang Miao , Liu Yun , Tang Pan , Huili Liu , Zhou Yanjun , Tong Guangzhi , Yu Lingxue , Li Guoxin , Deng Xiaoying 
Published: October 2023

Abstract
Background
Porcine deltacoronavirus (PDCoV), a novel swine enteropathogenic coronavirus, that causes acute diarrhea, vomiting, dehydration and mortality in neonatal piglets, resulting in significant economic losses to the swine industry worldwide. At present, there are no effective prevention and control measures for PDCoV.
Methods
We expressed the dimer receptor binding domain of PDCoV spike protein (RBD-dimer) and ferritin (SC-Fe) through the prokaryotic expression system, and successfully constructed RBD-Fe nanoparticles by covalentially coupling PDCoV RBD-dimer and SC-Fe using the SpyTag/SpyCatcher system. The immunoprotection of RBD-Fe nanoparticles was evaluated in mice.
Results
The boosting effect on immune responses of the homologous prime-boost regime showed that RBD-Fe nanoparticles promptly and efficiently elicited specific humoral and cellular immune responses in mice. Notably, PDCoV spike (S)-specific IgG and neutralizing antibody (NA) responses from the RBD-Fe group were detected in immunized mice. The histopathological results showed that immunization with RBD-Fe nanoparticles significantly enhanced the resistance of mice to PDCoV infection.
Conclusion
This study successfully developed a candidate nanoparticle vaccine, providing protection against virulent PDCoV in mice.
Predictors of Reflux Persistence After Endoscopic Dextranomer/Hyaluronic Acid Copolymer Injection for the First Time in Pediatric Patients with Vesicoureteral Reflux: Short-term Results
Authors: Yilmaz Ismail Onder , Akdogan Nebil , Deger Mutlu , Aridogan Ibrahim Atilla , Izol Volkan , Satar Nihat 
Published: October 2023

Abstract

This study aims to investigate the factors effective in predicting the persistence of reflux after the first subureteric transurethral injection (STING) of dextranomer/hyaluronic acid copolymer in pediatric patients with vesicoureteral reflux. The data of patients without a previous history of surgery to treat vesicoureteral reflux and who underwent STING for the first time between September 2011 and November 2020 were investigated retrospectively. After considering exclusion criteria, of 199 patients, 127 patients and 180 renal unit were suitable for inclusion. A renal unit-based evaluation was made. Age < 61 months (univariate: p = 0.001, multivariate: p = 0.015, HR: 2.352 (1.181–4.686), OR (95% CI)), moderate reflux level (grade 3) (univariate: p < 0.001, multivariate: p = 0.019, HR: 2.703 (1.177–6.209), OR (95% CI)), DRF (differential renal function) < 45 (univariate: p = 0.020, multivariate: p = 0.047, HR: 1.992 (1.009–3.935), OR (95% CI)), and UDR (ureteral diameter ratio) > 0.15 (univariate: p < 0.001, multivariate: p = 0.005, HR: 2.786 (1.368–5.672), OR (95% CI)) were found to be factors that negatively affected reflux resolution after STING surgery. In our study, UDR and DRF were found to be factors affecting reflux persistence. UDR and DRF should be considered in order to predict reflux resolution in patients who will undergo STING.
Low-grade inflammation in the prognosis of patients undergoing coronary artery bypass grafting: the value of neutrophil-to-lymphocyte ratio (NLR) and growth differentiation factor 15 (GDF15)
Authors: Garganeeva Alla A. , Kuzheleva Elena A. , Tukish Olga V. , Repin Alexey N. 
Published: October 2023

Abstract
Background
Predicting major adverse cardiovascular events (MACEs) after coronary interventions is an urgent and important task. Subclinical inflammation markers are becoming increasingly investigated for this purpose.
Aim
To determine the role of the neutrophil-to-lymphocyte ratio (NLR) and growth differentiation factor 15 (GDF-15) in predicting MACE in patients after coronary artery bypass grafting (CABG).
Methods
This prospective observational study included 80 patients with coronary artery disease who underwent CABG and were followed up for at least 1 year. In a prospective follow-up, a combined endpoint (MACE) had 27.5% (a total of 22 events).
Results
The values of GDF-15 and NLR were comparable in groups with and without MACE. A ROC analysis showed a low AUC for NLR (AUC = 0.566 (p = 0.363)) and GDF-15 (AUC = 0.621 (p = 0.096)). The value of the product GDF-15*NLR was determined. The median was 3108.05 (2069; 4145) for patients who did not have MACE and 4108.8 (2779.4; 5890.5) for patients with MACE (p = 0.010). This association remained after the introduction of amendments to sex, age, diabetes, and left ventricular ejection fraction.
Conclusions
The value of the product indicators NLR and GDF-15 is associated with the development of adverse cardiovascular events in patients after CABG.
Developing New Sustainable Pyridinium Ionic Liquids: From Reactivity Studies to Mechanism-Based Activity Predictions
Authors: Borikhonov Bakhtiyor , Berdimurodov Elyor , Kholikov Tursunali , Katin Konstantin P. , DEMİR Muslum , Sapaev Frunza , Turaev Sherzod , Jurakulova Nigora 
Published: October 2023

Abstract
Recently, pyridinium-based ionic liquids have been received great attention thanks to their unique features, such as low melting points, low volatility, high thermal stability, and moderate solvation properties. In the present work, for the first time, three pyridinium-based ionic liquids 1-(2-(isopentyloxy)-2-oxoethyl)pyridin-1-ium chloride, 1-(2-(hexyloxy)-2-oxoethyl)pyridin-1-ium chloride, and 1-(2-(benzyloxy)-2-oxoethyl)pyridin-1-ium chloride were synthesized by simply reacting pyridine with esters of monochloroacetic acid. The biological activities of as-prepared compounds were evaluated experimentally through plant growth promotion, herbicidal, and insecticidal assays The biological test results show thate benzyloxy derivative stimulated wheat and cucumber growth over 20% at lower doses. The isopentyloxy compound was the most effective herbicide, reducing root/stem growth by >80%.. To support experimental data, the computational methods including DFT calculations, molecular docking and druglikeness prediction were also applied. It was found that the benzyloxy salt had the highest predicted binding affinities and druglikeness and yield was for pure salt production is in 78-86%. An integrated experimental-computational approach provided insights into structure-activity relationships and mechanisms of action. The results showed the biological activity depends on substituent chain length/structure, influencing lipophilicity and membrane/target interactions. The findings support further development of optimized pyridinium ionic liquids as natural active agents for agriculture and pharmaceutical applications. These ionic salts are suggested as potential agent in agricultural, pharmaceutical and industrial application.
Construction of MoS 2 -rGO Hybrid Catalyst: An Efficient and Highly Stable Electrocatalyst for Enhanced Hydrogen Generation Reactions
Authors: Arunprasad Veeranan , Karthik P. Siva , Thulasi Selvam , Babu P. Sathish 
Published: October 2023

Abstract
It has been hypothesized that molybdenum disulfide, also known as MoS2, is an attractive option for the synthesis of hydrogen with a high degree of efficiency. It is preferred to construct a hybrid based on MoS2 in order to increase the catalytic efficiency, and it is vital to have a grasp of the nature of catalysis in order to make advances in this sector. In this paper, we use reduced graphene oxide, generally known as rGO, to create a MoS2@rGO hybrid catalyst with a number of favorable characteristics for the hydrogen evolution process (HER). The MoS2@rGO hybrids are next subjected to a battery of analytical tests, including TGA, XRD, TEM, XPS, Raman and BET. 1T MoS2@rGO hybrids demonstrated short Tafel slopes (46 and 52 mV.dec-1) and low levels of overall (70 and 71 mV versus RHE) in both alkaline and acidic electrolytes, allowing for a high current density of 10 mA.cm2. The findings show that HER exists in flawed heterostructures. Because 1T phase molybdenum disulfide (MoS2) has more functional sites and a higher intrinsic permeability, it is responsible for the catalyst's outstanding HER efficiency. This paper presents a novel way for fabricating highly active and responsive HER catalysts, as well as a way that is both feasible and practical for fabricating defective-MoS2@rGO heterostructures.