bluuebunny/crossref_metadata_2025_split huggingface dataset:
Central composite design approach for concurrent desulfurization and denitrogenation of model liquid fuel over Mo‐AAC
Authors: Sikarwar Prerana , Gosu Vijayalakshmi , Palla Venkata Chandra Sekhar , Subbaramaiah Verraboina 
Published: November 2023

AbstractThe primary objective of this work was to investigate the simultaneous removal of refractory sulfur (dibenzothiophene, DBT) and nitrogen compounds (indole, IND) from model gasoline. This research aimed to develop an efficient adsorption process to mitigate the emission of sulfur oxide and nitrogen oxides, which pose direct threats to human health and the environment. Additionally, the study focused on addressing technical challenges encountered in the refinery process, particularly the poisoning of catalysts due to the presence of these compounds. To achieve the study's goals, granular activated carbon (GAC) was subjected to acid treatment for modification. Molybdenum species were then incorporated into the acid‐treated GAC using the wet impregnation technique. The composition and distribution of elements on the surface of the modified GAC (Mo‐AAC) were analyzed via X‐ray photoelectron spectroscopy (XPS). Various characterization techniques were employed to confirm the uniform dispersion of molybdenum species on the GAC surface. The specific surface area of the adsorbent was increased from 257 m2/g to 316 m2/g following the acid treatment and molybdenum modification. The study explored the impact of several key parameters on the removal of DBT and IND using central composite design (CCD). A regression model was derived using CCD through hybrid central composite design, and its adequacy was verified with the means of tests such as analysis of variance (ANOVA), a lack of fit test, and residuals distribution consideration. Experimental results match well with the results obtained by CCD model, justifying the accuracy of models. The results showed that all four parameters have a significant impact on removal of DBT and IND. Increasing temperature and the adsorbent dose positively affected the removal of both DBT and IND, indicating that higher temperatures and greater adsorbent dosages improved removal efficiency. On the other hand, the concentration of DBT and IND had a negative impact, signifying that higher initial contaminant concentrations hindered removal efficiency. The study determined the optimum initial contaminant concentrations for DBT and IND, temperature, and adsorbent dose to be 186 mg/L, 50 mg/L, 25.5°C, and 32 g/L, respectively. These conditions yielded the highest removal efficiency. The research demonstrated that Mo‐AAC has the capability to effectively reduce the sulfur and nitrogen content of model gasoline, making it a promising solution for addressing environmental and refinery challenges associated with these compounds.
Ambivalence and Resistance in Contemporary Imaginations of US Capitalist Hinterlands
Authors: Valdés Olmos Tjalling 
Published: November 2023

AbstractAlthough conventionally imagined through the registers of the frontier, this chapter asks how the notion of the hinterland facilitates a different political understanding of the rural US West as affected by capitalism. While Phil Neel’s 2018 Hinterland makes the rural visible as an essential node in the infrastructure of global capitalism, this chapter explores how it also marks the rural US West as ruined and vacated of meaningful political resistance. Chloé Zhao’s film Nomadland, through an interlocution of the hinterland with the western and the road movie, imagines resistance in more ambivalent ways that emphasize capitalism’s interwovenness with heteronormativity and settler colonialism. Nevertheless, the affective economies at play in both representations reaffirm a settler colonial logic that erases Indigenous Americans as active political subjects.
The Hinterland at Sea
Authors: Peeren Esther 
Published: November 2023

AbstractThe hinterlands of contemporary global capital are as contested as those of the heydays of colonialism, but instead of as yet-to-be-developed, they manifest as overdeveloped, laid waste to. I explore what it means to live in a hinterland of abandonment by turning to Ben Smith’s Doggerland (2019), set on a windfarm in the North Sea in a dystopian future. This novel, I argue, not only literally places the hinterland at sea, but conceptualizes it as a realm of the at sea, of people, materials, and elements as constantly shifting and sifting in a struggle for survival unfolding at the scale of the protagonists’ lives and at that of the deep time narrative of water, which includes the prehistory of the North Sea as a landmass.
Hinterland, Underground
Authors: Wenzel Jennifer 
Published: November 2023

AbstractThis chapter adds a vertical dimension to the horizontal relations at work in hinterlands. From a metropolitan perspective, hinterlands are “back there,” “over yonder”: beyond the horizon. As Raymond Williams observed, such distinctions are complicated by the uneven economic and ecological metabolisms between country and city. But how are these metabolisms constituted by the subsoil: dynamic subterranean flows and stocks of matter and energy whose effects shape what might seem like stable ground? How are fossil fuel deposits lying beneath rural landscapes incorporated into geographic imaginaries of settler-colonial frontiers and agricultural heartlands? How does soil itself yoke surface to subsurface, hinterland to national and planetary politics? What social and political forces are at work in the hinterland underground?
The Coast Bouleverses at Kolkata
Authors: Mukherjee Rila 
Published: November 2023

AbstractThis chapter argues that “hinterland” is not only a designation related to the economic field, but also a perspective. As the sea is increasingly turned into land for developmental purposes, and as legal strategies transform coastal waters into land-like, developable components of state territory, hinterlands are transforming in nature. This process is markedly visible in Kolkata’s environs, where seemingly passive spaces have changed into active places where people create their own identities and histories.
Reclaiming the (Hinter)land: Lake Texcoco and the Airport That Never Was
Authors: Concheiro San Vicente Luciano , Nueno Guitart Xavier 
Published: November 2023

AbstractThe colonial history of the term “hinterland” speaks of a practice of territorial control allowing colonial powers to claim sovereignty of the region behind a port. In this chapter, we consider the violent history of a construction of a new airport for Mexico City in Texcoco’s Lake as the active production of a hinterland through land reclamation. Although mostly drained in 1900 by what was then the most important engineering works worldwide, Lake Texcoco continues to manifest itself as a key actor that shapes the forms of territorialization and different uses of space, whether as agricultural land, as international airport, or as ecological park. The soil—saline, unstable, and shifting—gives meaning to the multiple conflicts surrounding the failed attempts to construct the new airport.
Displacing a Right to Act Communally Within Community Relocation
Authors: Jerolleman Alessandra , Marino Elizabeth , Jessee Nathan , Koslov Liz , Comardelle Chantel , Villarreal Melissa , de Vries Daniel , Manda Simon 
Published: November 2023

AbstractDespite the widely proclaimed principle of “community-led” processes within climate adaptation discourse, individuals’ assertion of a right to act communally is often undercut by the law, the application of the law, and planning conventions. The previous chapter emphasized some of the profound challenges associated with individual choice and community action during the administration of buyout programs.
Improving the Accuracy
Authors: Sundnes Joakim 
Published: November 2023

AbstractAs mentioned previously, the FE method derived in Chapter 1 is not the most sophisticated ODE solver. Although it provides sufficient accuracy for most of the applications covered in this book, there are alternative methods available that offer improved accuracy and stability, making them better suited for solving challenging ODE systems. In this chapter, we will focus on enhancing accuracy, and thus we will primarily explore explicit methods. Implicit methods, which exhibit superior stability properties and are better suited for solving stiff ODEs, will be discussed in Chapter 3.
Modeling Infectious Diseases
Authors: Sundnes Joakim 
Published: November 2023

AbstractThroughout this book we have focused entirely on solving ODEs, without delving deeply into their origins or applications. In the present chapter we shift our attention to modeling with ODEs, by exploring a widely studied class of ODE models that describe the spread of infectious diseases. This group of models serves as a good example of how a complex phenomenon can be modeled using relatively simple systems of ODEs. We will derive these models based on a set of fundamental assumptions and discuss the limitations that arise from these assumptions. Although we consider a single application and a single class of models, the fundamental steps of the modeling process are applicable to a wide range of real-world phenomena.
A hamstring autograft diameter ≤ 8 mm is a safe option for smaller, lighter and female athletes who want to return to pivoting sports after ACL reconstruction
Authors: Boots Nicole , van Melick Nicky , Bogie Rob 
Published: November 2023

AbstractPurposeTo investigate the association between hamstring autograft diameter and ACL graft failure rate in athletes who successfully returned to pivoting sports after ACL reconstruction.MethodsRetrospective evaluation of ACL graft failure rates in athletes who underwent ACL reconstruction with all‐inside hamstring autograft and successfully returned to pivoting sports following postoperative rehabilitation. Athletes were divided into a ≤ 8 mm group and a > 8 mm group. Data about return to pivoting sports and ACL graft failures after ACL reconstruction were collected via a digital questionnaire. ACL graft failures were in all cases confirmed by an orthopaedic surgeon and/or MRI. The association between hamstring autograft diameter and ACL graft failure rate was investigated using a Fisher’s exact test in the subgroup of athletes who completed the digital questionnaire and returned to pivoting sports.ResultsTwo‐hundred and twenty‐nine of the 422 athletes who completed the digital questionnaire (54.2%) returned to a pivoting sport and were included for final analyses. Ninety‐seven (42.4%) of the athletes who returned to sport were in the ≤ 8 mm group (8 graft failures) and 132 (57.6%) in the > 8 mm group (10 graft failures). There were significantly more women (49.5 and 13.6% respectively; p < 0.001) and significantly smaller (1.75 and 1.81 m respectively; p < 0.001), lighter (72.2 and 79.6 kg respectively; p < 0.001) and younger (23.6 and 26.1 years old respectively; p = 0.015) athletes in the ≤ 8 mm group compared to the > 8 mm group. There was no significant association between hamstring autograft diameter and ACL graft failure rate.ConclusionA hamstring autograft diameter of ≤ 8 mm is a legitimate option for smaller, lighter and female athletes without increasing the risk for ACL graft failure.Level of evidenceIII.
Cellulomonas endometrii sp. nov.: a novel bacterium isolated from the endometrial microbiota
Authors: Abou Chacra Linda , Bonnet Marion , Heredia Mégane , Haddad Gabriel , Armstrong Nicholas , Alibar Stéphane , Bretelle Florence , Fenollar Florence 
Published: November 2023

AbstractAn isolate of a bacterium recovered from an endometrial biopsy failed to be identified by MALDI-TOF mass spectrometry and was subjected to 16S rRNA sequencing. The obtained sequence was compared by BLASTn against the NCBI database, which revealed that the most closely related species was Cellulomonas hominis and Cellulomonas pakistanensis, with 98.85% and 98.45% identity, respectively. Phenotypic characterisation and genome sequencing were performed. The isolate was facultative anaerobic, gram-positive, motile, non-spore forming, and rod-shaped. Cell wall fatty acid profiling revealed that 12-methyl-tetradecanoic acid was the most abundant fatty acid (36%). The genome size was 4.25 Mbp with a G + C content of 74.8 mol%. Genomic comparison of species closely related to this strain showed that all digital DNA–DNA hybridisation (dDDH) and mean orthologous nucleotide identity (OrthoANI) values were below published species thresholds (70% and 95–96%, respectively). Based on these data, we conclude that this isolate represents a new bacterial species belonging to the family Cellulomonadaceae and the phylum Actinomycetota. We propose the name Cellulomonas endometrii sp. nov. The type strain is Marseille-Q7820T (= CSUR Q7820 = CECT 30716).
Comprehensive profiling and semi-quantification of exogenous chemicals in human urine using HRMS-based strategies
Authors: Gutiérrez-Martín Daniel , Restrepo-Montes Esteban , Golovko Oksana , López-Serna Rebeca , Aalizadeh Reza , Thomaidis Nikolaos S. , Marquès Montse , Gago-Ferrero Pablo , Gil-Solsona Rubén 
Published: November 2023

AbstractChemicals infiltrate our daily experiences through multiple exposure pathways. Human biomonitoring (HBM) is routinely used to comprehensively understand these chemical interactions. Historically, HBM depended on targeted screening methods limited to a relatively small set of chemicals with triple quadrupole instruments typically. However, recent advances in high-resolution mass spectrometry (HRMS) have facilitated the use of broad-scope target, suspect, and non-target strategies, enhancing chemical exposome characterization within acceptable detection limits. Despite these advancements, establishing robust and efficient sample treatment protocols is still essential for trustworthy broad-range chemical analysis. This study sought to validate a methodology leveraging HRMS-based strategies for accurate profiling of exogenous chemicals and related metabolites in urine samples. We evaluated five extraction protocols, each encompassing various chemical classes, such as pharmaceuticals, plastic additives, personal care products, and pesticides, in terms of their extraction recoveries, linearity, matrix effect, sensitivity, and reproducibility. The most effective protocol was extensively validated and subsequently applied to 10 real human urine samples using wide-scope target analysis encompassing over 2000 chemicals. We successfully identified and semi-quantified a total of 36 chemicals using an ionization efficiency-based model, affirming the methodology’s robust performance. Notably, our results dismissed the need for a deconjugation step, a typically labor-intensive and time-consuming process.
Graphical Abstract
Chemokine receptor–targeted PET/CT provides superior diagnostic performance in newly diagnosed marginal zone lymphoma patients: a head-to-head comparison with [18F]FDG
Authors: Kosmala Aleksander , Duell Johannes , Schneid Simone , Serfling Sebastian E. , Higuchi Takahiro , Weich Alexander , Lapa Constantin , Hartrampf Philipp E. , Raderer Markus , Einsele Hermann , Buck Andreas K. , Topp Max S. , Schlötelburg Wiebke , Werner Rudolf A. 
Published: November 2023

Abstract
Background
In patients with marginal zone lymphoma (MZL), [18F]FDG PET/CT provided inconsistent diagnostic accuracy. C-X-C motif chemokine receptor 4 (CXCR4) is overexpressed in MZL and thus, may emerge as novel theranostic target. We aimed to evaluate the diagnostic performance of CXCR4-targeting [68Ga]Ga-PentixaFor when compared to [18F]FDG PET/CT in MZL.

Methods
Thirty-two untreated MZL patients (nodal, n = 17; extranodal, n = 13; splenic, n = 2) received [68Ga]Ga-PentixaFor and [18F]FDG PET/CT within median 2 days. We performed a visual and quantitative analysis of the total lymphoma volume by measuring maximum/peak standardized uptake values (SUVmax/peak), and calculating target-to-background ratios (TBR, defined as lesion-based SUVpeak divided by SUVmean from blood pool). Visual comparisons for both radiotracers were carried out for all target lesions (TL), and quantitative analysis of concordant TL evident on both scans. Last, MZL subtype analyses were also conducted.

Results
On a patient-based level, [68Ga]Ga-PentixaFor identified MZL manifestations in 32 (100%) subjects (vs. [18F]FDG, 25/32 [78.1%]). Of the 256 identified TL, 127/256 (49.6%) manifestations were evident only on CXCR4-directed imaging, while only 7/256 (2.7%) were identified on [18F]FDG but missed by [68Ga]Ga-PentixaFor. In the remaining 122/256 (47.7%) concordant TL, [68Ga]Ga-PentixaFor consistently provided increased metrics when compared to [18F]FDG: SUVmax, 10.3 (range, 2.53–37.2) vs. 5.72 (2.32–37.0); SUVpeak, 6.23 (1.58–25.7) vs. 3.87 (1.54–27.7); P < 0.01, respectively. Concordant TL TBR on [68Ga]Ga-PentixaFor (median, 3.85; range, 1.05–16.0) was also approximately 1.8-fold higher relative to [18F]FDG (median, 2.08; range, 0.81–28.8; P < 0.01). Those findings on image contrast, however, were driven by nodal MZL (P < 0.01), and just missed significance for extranodal MZL (P = 0.06).

Conclusions
In newly diagnosed MZL patients, [68Ga]Ga-PentixaFor identified more sites of disease when compared to [18F]FDG, irrespective of MZL subtype. Quantitative PET parameters including TBR were also higher on [68Ga]Ga-PentixaFor PET/CT, suggesting improved diagnostic read-out using chemokine receptor-targeted imaging.
CXC chemokine ligand 13 and galectin-9 plasma levels collaboratively provide prediction of disease activity and progression-free survival in chronic lymphocytic leukemia
Authors: Ahmed Heba A. , Nafady Asmaa , Ahmed Eman H. , Hassan Emad Eldin Nabil , Soliman Walaa Gamal Mohamed , Elbadry Mahmoud I. , Allam Ahmed Ahmed 
Published: November 2023

AbstractThe clinical outcome of lymphocytic leukemia (CLL) is quite heterogeneous. The purpose of this observational study was to investigate the clinical merit of measuring plasma galectin-9 and CXCL-13 concentrations as predictors of CLL activity, prognosis, and early indicators of therapeutic response. These biomarkers were compared with other prognostic indicators, progression-free survival (PFS), time to first treatment (TTT), and overall survival (OS) over a follow-up period (4 years). First, plasma galectin-9 and CXCL-13 concentrations were analyzed in CLL patients at the time of diagnosis as well as healthy controls. Compared to controls, CLL patients had significantly higher serum levels of CXCL-13 and galectin-9. Second, we observed that CLL patients with high soluble CXCL-13 and galectin-9 levels had advanced clinical stages, poor prognosis, 17p del, short PFS, short TTT, and therapy resistance. The levels of CXCL-13, β2-microglobulin, LDH, CD38%, and high grade of Rai-stage were all strongly correlated with the galectin-9 levels. Soluble CXCL-13 and galectin-9 had very good specificity and sensitivity in detecting CLL disease progression and high-risk patients with the superiority of galectin-9 over CXCL-13. Although the two biomarkers were equal in prediction of TTT and treatment response, the soluble CXCL13 was superior in prediction of OS. High CXCL-13 and galectin-9 plasma levels upon CLL diagnosis are associated with disease activity, progression, advanced clinical stages, short periods of PFS, short TTT, and unfavorable treatment response.
Digitale Plattformen zur Vermittlung informell Helfender für die häusliche Pflege: Welchen Nutzen sehen Anbieter?
Authors: Wörle Tobias , Geiselhart Jochen , Haushammer Christian , Bernhard Dominik 
Published: November 2023

Zusammenfassung
Hintergrund
Über den tatsächlichen Nutzen digitaler Plattformangebote, die engagementbereite Personen an Haushalte mit Pflegeaufgaben vermitteln, ist bisher wenig bekannt.

Ziel
Der Beitrag stellt erste Ergebnisse einer Vermittlungsanbieterbefragung als Teil einer mehrstufig angelegten Interviewstudie vor. Im Zentrum steht zunächst die Frage, welche Nutzenaspekte Anbieter ihren Angeboten im Hinblick auf die eigene Organisation, die Nutzer:innen sowie auf gesellschaftlicher oder sozialräumlicher Ebene zuschreiben.

Material und Methoden
Für leitfadengestützte Interviews wurden Vermittlungsanbieter ausgewählt. Zwei davon nutzen eine Matching-Plattform, zwei nicht. Die Daten wurden über inhaltsanalytische Verfahren ausgewertet.

Ergebnisse
Effizienzvorteile, Qualitätsgewinne, aber auch neue Möglichkeiten zur Erschließung weiterer Helferklientele sind aus Anbietersicht wichtige Nutzenaspekte digitaler Matching-Plattformen für die eigene Organisation. Um Vertrauen und Akzeptanz aufseiten der Nutzenden zu fördern, erscheinen hybrid gestaltete Vermittlungsmodelle besonders vorteilhaft. Sie ermöglichen neben der Nutzung digitaler Technologien zugleich persönliche Begleitung im Aufbau von Hilfebeziehungen. Die Befunde legen zudem nahe, dass gemeinwohlorientierte, qualitätsgesicherte Vermittlungsplattformen auch auf sozialräumlicher Ebene Nutzenvorteile entfalten können.

Diskussion und Fazit
Neben Nutzenaspekten in Bezug auf die eigene Organisation und auf Nutzer:innen konnten auch nutzenstiftende Potenziale in Bezug auf lokale Sorgenetzwerke rekonstruiert werden.
Real-world experience with ultrasound renal denervation utilizing home blood pressure monitoring: the Global Paradise System registry study design
Authors: Mahfoud Felix , Azizi Michel , Daemen Joost , Sharp Andrew S. P. , Patak Atul , Iglesias Juan F. , Kirtane Ajay , Fisher Naomi D. L. , Scicli Andrea , Lobo Melvin D. 
Published: November 2023

Abstract
Background
Hypertension is a major public health issue due to its association with cardiovascular disease risk. Despite the availability of effective antihypertensive drugs, rates of blood pressure (BP) control remain suboptimal. Renal denervation (RDN) has emerged as an effective non-pharmacological, device-based treatment option for patients with hypertension. The multicenter, single-arm, observational Global Paradise™ System (GPS) registry has been designed to examine the long-term safety and effectiveness of ultrasound RDN (uRDN) with the Paradise System in a large population of patients with hypertension.

Methods
The study aims to enroll up to 3000 patients undergoing uRDN in routine clinical practice. Patients will be recruited over a 4-year period and followed for 5 years (at 3, 6, and 12 months after the uRDN procedure and annually thereafter). Standardized home BP measurements will be taken every 3 months with automatic upload to the cloud. Office and ambulatory BP and adverse events will be collected as per routine clinical practice. Quality-of-Life questionnaires will be used to capture patient-reported outcomes.

Conclusions
This observational registry will provide real-world information on the safety and effectiveness of uRDN in a large population of patients treated during routine clinical practice, and also allow for a better understanding of responses in prespecified subgroups. The focus on home BP in this registry is expected to improve completeness of long-term follow-up and provide unique insights into BP over time.

Graphical abstract
Global Paradise System registry study design. ABP, ambulatory blood pressure; BP, blood pressure; FU, follow-up; M, month; OBP, office blood pressure.