bluuebunny/crossref_metadata_2025_split huggingface dataset:
Case Report: Mutation in TNNI3(c. 544G>A): a novel likely pathogenic mechanism of neonatal dilated cardiomyopathy
Authors: Li Xianhong , Dai Liying , Zhang Jian 
Published: November 2023

BackgroundDilated cardiomyopathy (DCM) is a rare disease that causes heart failure due to malfunction of the heart muscle characterized by left ventricular dilation and poor systolic function. Genetic screening leads to advantages in early diagnosis and prognostic assessment of patients with suspected inherited cardiomyopathies. Here, we report a case of neonatal dilated cardiomyopathy due to a mutation of the TNNI3 gene, which has not been published in neonatal dilated cardiomyopathy before.Case presentationThe patient was a 22-day-old newborn boy with poor ability to respond to stimuli, presenting with shortness of breath over 11 days. He presented with irregular fever, tachypnea, difficulty in ventilator withdrawal, and mild edema of both lower limbs, and III/6SM could be heard in the precardiac area. He presented repeated weaning difficulties during hospitalization with intractable low EF heart insufficiency. Doppler echocardiography showed refractory low ejection fraction, cardiac enlargement, cardiac insufficiency, mild pulmonary hypertension, and mitral and tricuspid insufficiency with mild valve regurgitation. Whole-exome sequencing showed a mutation in the TNNI3 gene, c. 544G&gt;A (p.Glu182Lys). Thus, he was diagnosed with neonatal DCM. There was no mutation in the parents, the child died 2 weeks after discharge.ConclusionsTNNI3 mutation is a novel likely pathogenic mechanism of neonatal dilated cardiomyopathy. Therefore, systematic use of diagnostic tools, advanced risk models, and a deeper understanding of the mechanism are required to reduce morbidity and mortality in this disease.
Availability of emergency contraception in large Brazilian municipalities: a guaranteed right?
Authors: Pinheiro Ana Carolina Gomes , Alves Bárbara Manuella Cardoso Sodré , Pedrosa Claudia Mara , dos Reis Tiago Marques , Bertoldi Andréa Dâmaso , Zimmermann Ivan Ricardo , Leite Silvana Nair , Santana Rafael Santos 
Published: November 2023

Introduction: Emergency Contraception (EC) is available in Brazil since 1996, when it was adopted as one if the family planning strategies and, in 1998, for use in services assisting victims of sexual violence. In the country, its use is regulated by guidelines. Its access through SUS (Unified Health System), however, does not seem to occur in a standardized manner.Methods: The aim of the study was to analyze the availability and barriers to accessing emergency contraception (levonorgestrel) in Brazilian municipalities with more than 500 thousand inhabitants. The survey was carried out by a form sent to the Municipal Health Departments (SMS) managers and a search on the list of standardized medicines by the hospitals in the same municipalities.Results: The Basic Health Units were identified as the standard access places to EC. However, one of the obstacles mentioned is the need for a prescription for dispensing in almost 80% of the analyzed cities. Access in emergency situations at night and on weekends is also uncertain, since although 67% of the places stated that they dispense at the hospital level, the item was only standardized in 21% of the hospital lists.Discussion: The difficult access this drug in the public system essentially tends to harm the poorest women, who are the ones who suffer most from the consequences of an unwanted pregnancy.
The effect of emotional motivation on strategy flexibility: the moderating role of task load
Authors: Wang Yun , Zhu Chuanlin , Zuo Dan , Liu Jingyi , Liu Dianzhi 
Published: November 2023

IntroductionResearch has demonstrated that cognitive flexibility is associated with academic achievement, with poorer cognitive flexibility being linked to poorer academic performance. Strategy conversion is an example of cognitive flexibility, which requires individuals to quickly and flexibly switch between strategies depending on the task at hand. Studies have investigated the impact of emotional motivation on cognitive flexibility, with varying results. Furthermore, research has indicated that a high task load increases psychological burden and reduces cognitive flexibility, but few studies have analyzed the impact of task load on the relationship between emotional motivation and cognitive flexibility. This study sought to investigate the effect of emotional motivation on cognitive flexibility based on strategy switching, and the moderating effect of task load.MethodsThree experiments were conducted. Experiment 1 used forced conversion paradigm with a moderate task load that required participants to estimate tasks using a given strategy. Experiment 2 employed matched conversion paradigm with a high task load, informing participants of the strategies to be used but without any clues, necessitating the selection and execution of appropriate strategies based on the question features. Experiment 3 adopted free conversion paradigm with a relatively low task load, allowing participants to freely choose and execute strategies without any correctness or error criteria.ResultsThe intensity and direction of emotional motivation have a complicated and fluctuating impact on the flexibility to utilize strategies. When the task workload is high, the intensity of emotional motivation has a significant impact on strategy utilization flexibility, with low approach motivation being more conducive to flexibility. Conversely, when the task workload is low, the direction of emotional motivation has a greater effect, with high avoidance motivation being more advantageous.DiscussionThis study demonstrated that high workload could bring about a low intensity advantage, while low workload could induce an avoidance direction advantage, suggesting that task load could moderate the impact of emotional motivation on arithmetic strategy utilization flexibility, and avoidance motivation is not always detrimental to cognitive flexibility.
RETRACTED: Structural equation modeling to estimate treatment adherence based on the light triad of personality and sense of coherence in patients with type-2 diabetes: examining the mediating role of psychological well-being
Authors: Mousavi Seyedeh Maryam , Bagheri Seyedeh Masoumeh , Jalali Heris Nasrin , Matbouraftar Parisa , Azarian Mozhdeh , Kordbagheri Mohammadreza 
Published: November 2023

BackgroundThe current study investigated the relationship between the light triad of personality and self-coherence with treatment adherence in patients with Type 2 Diabetes Mellitus (T2DM) using Structural Equation Modeling (SEM). Psychological well-being was considered a mediator variable in this SEM assessment.MethodA cross-sectional study by convenience sampling was conducted, and 368 patients with T2DM were recruited from 10 private practice and general hospitals from May to November 2021 in Gilan province, Iran. The Reef’s Psychological Well-being Questionnaire, the Light Triad Rating Scale, and Antonovsky’s Sense of Coherence Scale were used for data collection. Structural equation modeling was used to examine the model fitness and identify direct/indirect relationships among variables. Data were analyzed by the SPSS (Version 26) and AMOS software (Version 24).ResultsThe average score of light triads, sense of coherence, psychological well-being, and treatment adherence were 70.36 ± 25.55, 108.25 ± 37.68, 57.03 ± 23.84, and 106.81 ± 39.61, respectively. Model fit statistics suggest that the measurement model fits the data well: χ2 (146, N = 368) = 314.011 (p &lt; 0.001). The SEM results showed that the light triad of personality (β = 0.12) and self-coherence (β = 0.14) were positively associated with treatment adherence. Anxiety, the light triad of personality (β = 0.12), and self-coherence (β = 0.14) affect treatment adherence indirectly through psychological well-being.ConclusionThe analysis of the SEM revealed that the suggested model had a suitable goodness of fit. So, using self-coherence and psychological well-being structures in designing interventional programs is recommended to optimize treatment adherence in patients with T2DM.
Anti-depressant medication use is a risk factor for incident knee surgery and opioid use in patients with knee osteoarthritis
Authors: Zheng Yongqiang , Zhang Jinshan , Wang Zefeng , Liu Xiaofeng , Xu Yongquan , Fang Yangzhen , Lin Zhenyu , Lin Liang 
Published: November 2023

ObjectiveTo investigate whether depression and exposure to anti-depressant medication are independent risk factors for incident knee surgery and opioid use in knee osteoarthritis (KOA) patients.MethodsWe identified all patients who visited our outpatient department and were clinically diagnosed with KOA between January 2010 and January 2018. We retrieved their demographic, clinical, and radiographic data from the database of our hospital. Next, we analyzed the effect of depression and anti-depressant medication on the incident knee surgery and opioid use in KOA patients.ResultsA total of 4,341 KOA patients were found eligible to form the study population. Incident knee surgery and opioid use for the purpose of treating osteoarthritis were observed in 242 and 568 patients, respectively. Incident knee surgery was significantly associated with age (OR [95%CI], 1.024 [1.009–1.039], P = 0.002), BMI (OR [95%CI], 1.090 [1.054–1.128], P &lt; 0.001), baseline K-L grade 3 (OR [95%CI], 1.977 [1.343–2.909], P = 0.001), baseline K-L grade 4 (OR [95%CI], 1.979 [1.241–3.157], P = 0.004), depression (OR [95%CI], 1.670 [1.088–2.563], P = 0.019), and exposure to anti-depressant medication (OR [95%CI], 2.004 [1.140–3.521], P = 0.016). Incident opioid use was significantly associated with depression (OR [95%CI], 1.554 [1.089–2.215], P = 0.015) and exposure to anti-depressant medication (OR [95%CI], 1.813 [1.110–2.960], P = 0.017).ConclusionDepression and anti-depressant drug exposure were independently associated with incident knee surgery, highlighting the need for more attention on comorbid depression in KOA management.
The relationship of climate change awareness and psychopathology in persons with pre-existing mental health diagnoses
Authors: Gebhardt Nadja , Schwaab Lukas , Friederich Hans-Christoph , Nikendei Christoph 
Published: November 2023

IntroductionPersons with pre-existing mental health diagnoses are known to be more vulnerable to the consequences of climate change, such as extreme weather events and rising temperatures. However, it remains unclear if this holds true for adverse effects of climate change awareness, too.MethodsN = 89 patients of a psychosomatic outpatient clinic were assessed with well-established mental health questionnaires (PHQ-9 for depressive, GAD-7 for anxious, and PTSS-10 for post-traumatic symptoms) in their original form and in a modified version (PHQ-9-C, GAD-7-C, PTSS-10-C) specifically asking for patients’ symptom load regarding climate change awareness, and instruments evaluating personality factors (OPD-SF, SOC, RQ).Results21% of the sample reported at least mild symptoms of anxiety regarding climate change awareness, and 11% mild symptoms of depression due to climate change awareness. General anxiety (GAD-7) scores significantly predicted if people reported any psychological symptoms due to climate change awareness. In multiple regression analyses, higher scores of clinical symptoms of depression, anxiety or post-traumatic stress predicted higher scores of depressive, anxious or post-traumatic symptoms regarding climate change awareness, and higher scores of psychological symptoms regarding climate change awareness predicted each other. Younger participants reported significantly more traumatic symptoms regarding climate change awareness.DiscussionThe reported mental health impairments regarding climate change awareness in persons with pre-existing mental health diagnoses indicate an increased vulnerability. Hereby, depressive mental health burden seems to induce a predominantly depressive processing of climate change resulting in climate chance related depression. This holds also true for anxious and traumatic symptoms, and points toward biased attentional and memory processes and mood congruent processing.
Serological evidence of virus infection in Eidolon helvum fruit bats: implications for bushmeat consumption in Nigeria
Authors: Cantoni Diego , Mayora-Neto Martin , Derveni Mariliza , da Costa Kelly , Del Rosario Joanne , Ameh Veronica O. , Sabeta Claude T. , Auld Bethany , Hamlet Arran , Jones Ian M. , Wright Edward , Scott Simon D. , Giotis Efstathios S. , Banyard Ashley C. , Temperton Nigel 
Published: November 2023

IntroductionThe Eidolon helvum fruit bat is one of the most widely distributed fruit bats in Africa and known to be a reservoir for several pathogenic viruses that can cause disease in animals and humans. To assess the risk of zoonotic spillover, we conducted a serological survey of 304 serum samples from E. helvum bats that were captured for human consumption in Makurdi, Nigeria.MethodsUsing pseudotyped viruses, we screened 304 serum samples for neutralizing antibodies against viruses from the Coronaviridae, Filoviridae, Orthomyxoviridae and Paramyxoviridae families.ResultsWe report the presence of neutralizing antibodies against henipavirus lineage GH-M74a virus (odds ratio 6.23; p &lt; 0.001), Nipah virus (odds ratio 4.04; p = 0.00031), bat influenza H17N10 virus (odds ratio 7.25; p &lt; 0.001) and no significant association with Ebola virus (odds ratio 0.56; p = 0.375) in this bat cohort.ConclusionThe data suggest a potential risk of zoonotic spillover including the possible circulation of highly pathogenic viruses in E. helvum populations. These findings highlight the importance of maintaining sero-surveillance of E. helvum, and the necessity for further, more comprehensive investigations to monitor changes in virus prevalence, distribution over time, and across different geographic locations.
Influence of the practice of physical exercise and healthy eating on the Vigour of university lectures
Authors: Monserrat Hernández Montserrat , Arjona Garrido Ángeles , Checa Olmos Juan Carlos , Casimiro Andújar Antonio , Artés Rodríguez Eva María , Salguero García Darío 
Published: November 2023

IntroductionVigour at work is characterized by high levels of energy and high desire to make an effort at work. This article is the result of a research carried out with university teachers in Spain whose main objective is to show what type and frequency of physical exercise and diet influence Vigour.MethodsThe sample consisted of 121 subjects, 62% of whom were women and 37.2% men. A questionnaire was administered to collect information on sociodemographic data, physical exercise habits, eating habits and Vigour at work. Cross-tabulations of the dimensions of Vigour with sex, age and type of contract offered were performed. Spearman correlations and Correspondence Analysis are also carried out to provide information on the intensity and type of relationships between the Vigour dimensions. Finally, the influence of the frequency of physical exercise and diet on Total Vigour is investigated.ResultsThe results show that the relationships between the dimensions are very strong (sig = 0.001). In addition, the practice of moderate-high intensity physical exercise and maintaining a good adherence to the Mediterranean Diet is related to high levels of Total Vigour (F = 7.955; sig = 0.006). As for the influence of the sociodemographic variables used, significant differences were only observed in the Physical Strength dimension for sex (X2 = 6.173; p = 0.046) and age (X2 = 9.449; p = 0.051) and, with respect to the type of contract, in Emotional Energy (X2 = 19.487; p &lt; 0.001).Discusión and conclusionsThe main conclusions of our study show that practicing physical exercise of medium-high intensity four hours or more per week and a high adherence to the MD is more related to high Vigour levels than just eating well or just practicing exercise. And more studies are needed on the influence of sociodemographic variables on Vigour and its different dimensions.
From future diets to dishes: communicating dietary shift associated with a 1.5°C scenario for Brazil, China, Sweden and the United Kingdom
Authors: Lee Susan , Freer Muir , Wood Ruth , Edelenbosch Oreane , Sharmina Maria , Doelman Jonathan , van Vuuren Detlef , Wilson Charlie 
Published: November 2023

IntroductionWith the pressing need to mitigate greenhouse gas emissions, this study aims to simplify complex data from Integrated Assessment Models (IAMs). It focuses on identifying dietary shifts that align with the 1.5°C global warming limit as stipulated by the Paris Agreement.MethodsThe research utilises the IMAGE Integrated Assessment Model and applies the Diets, Dishes, Dish Ingredients (DDDI) communication framework. This methodology enables the visualisation of potential dietary and dish composition changes, thereby making the data more comprehensible to a broader audience.ResultsThe study effectively translates traditional IAM outputs into accessible visualisations. These visual tools provide a nuanced understanding of a low greenhouse gas diet, extending its relevance beyond academia to include professionals in diet and nutrition.DiscussionThis research stands as a significant advancement in the field, lowering the barrier to understanding sustainable diets for the future. It enriches the existing dialogue on dietary change and climate goals and serves as a catalyst for further research and practical applications in diverse contexts.
Representation of Fractional Operators Using the Theory of Functional Connections
Authors: Mortari Daniele 
Published: November 2023

This work considers fractional operators (derivatives and integrals) as surfaces f(x,α) subject to the function constraints defined by integer operators, which is a mandatory requirement of any fractional operator definition. In this respect, the problem can be seen as the problem of generating a surface constrained at some positive integer values of α for fractional derivatives and at some negative integer values for fractional integrals. This paper shows that by using the Theory of Functional Connections, all (past, present, and future) fractional operators can be approximated at a high level of accuracy by smooth surfaces and with no continuity issues. This practical approach provides a simple and unified tool to simulate nonlocal fractional operators that are usually defined by infinite series and/or complicated integrals.
SYSTEMATIC LITERATURE REVIEW: FENOMENOLOGI MODERASI BERAGAMA ISLAM DAN KRISTEN DI MALUKU BERDASARKAN BUDAYA PELA GANDONG
Authors: Dominggus Dicky 
Published: November 2023

Dalam kehidupan masyarakat yang majemuk pada masa kini, moderasi merupakan pembahasan yang menarik untuk diperbincangkan. Maluku merupakan daerah percontohan dalam hal moderasi beragama. Pelaksanaan moderasi di Maluku dapat berjalan optimal karena didasarkan pada berbagai kearifan lokal yang salah satunya adalah Pela Gandong. Metode yang digunakan dalam penelitian ini adalah Systematic Literature Review (SLR) terhadap artikel jurnal yang terbit pada tahun 2018-2022. Dalam penelitian terdapat tiga research question yakni apakah Pela Gandong memiliki peranan dalam moderasi beragama Islam dan Kristen di Maluku? Faktor apakah yang mempengaruhi Pela Gandong dapat berperan dalam moderasi beragama Islam dan Kristen di Maluku? Bagaimana bentuk dalam moderasi beragama Islam dan Kristen di Maluku dalam Pela Gandong? Adapun hasil yang diperoleh dari penelitian ini adalah Pela Gandong memiliki peranan dalam moderasi beragama Islam dan Kristen di Maluku. Adapun penyebab dari begitu kuat peranan Pela Gandong dalam moderasi beragama di Maluku disebabkan Pela Gandong itu sendiri sebagai ikatan persaudaraan yang sudah terbangun sejak zaman leluhur. Mengenai bentuk, Pela Gandong dalam moderasi beragama di Maluku adalah persaudaraan antar dua negeri (desa) yang dirumuskan dalam bentuk perjanjian di mana kedua pihak harus menyepakati dan tidak boleh melanggar satu sama lain.
ﺍﻟﻨﺘﺎﺟﺎﺕ ﺍﻷﺩﺑﻴﺔ ﻭﺍﻟﻤﺮﻛﺰﻳﺔ ﻟﺸﺎﻟﻮﻡ ﻋﻠﻴﺨﻢ
Authors: Shaimaa Fadel Hamoudi  
Published: November 2023

وﻟد اﻟﻛﺎﺘب واﻷدﻴب اﻟﻴﻬودي ﺸﺎﻟوم ﻋﻠﻴﺨم ﻓﻲ اﻟﺜﺎﻟث ﻤن ﻤﺎرس ﻋﺎم ١٨٥٩ ﻓﻲ ﻤدﻴﻨﺔ ﺒرﺴﻴﻼف
ﺸرق ﻛﻴﻴف (ﻋﺎﺼﻤﺔ أوﻛ ارﻨﻴﺎ ﺤﺎﻟﻴﺎً) واﻟﺘﻲ ﻛﺎﻨت ﺠزًء ﻤن اﻻﺘﺤﺎد اﻟﺴوﻓﻴﺘﻲ ٬ اﺴﻤﻪ اﻟﺤﻘﻴﻘﻲ ﺴﻠوﻤون
رﻓﻴﻨوﻓﻴﺘس وﻟﻘد ﻟﻘب ﻨﻔﺴﻪ ﺒـ (ﺸﺎﻟوم ﻋﻠﻴﺨم) ﺤﻴث ﻛﺎن ﻴوﻗـّﻊ ﺠﻤﻴﻊ ﻨﺘﺎﺠﺎﺘﻪ ﺘﺤت ﻫذا اﻻﺴم اﻟذي اﺸﺘﻬر ﺒﻪ

ﻓﻴﻤﺎ ﺒﻌد...
ﻗﻀﻰ ﺴﻨواﺘﻪ اﻷوﻟﻰ وﻫو ﻴﻌﻴش ﻓﻲ ﻤدﻴﻨﺔ ﺼﻐﻴرة وﻀﻴﻘﺔ وﻗد أﺜر ذﻟك ﻓﻲ ﻨﺘﺎﺠﺎﺘﻪ ﻻﺤﻘﺎً.. ﻛﺎن
أﺒوﻩ ﻤﻨﺎﺤﻴم ﻨﺎﺤوم رﻓﻴﻨوﻓﻴﺘس ﺤﺎﺨﺎﻤﺎً وﻗد ﺘوﺠﻪ ﻓﻲ ﺘﻌﻠﻴﻤﻪ إﻟﻰ ﺤرﻛﺔ اﻟﻬﺴﻛﺎﻻﻩ (اﻟﺘﻨوﻴر) أي إﻟﻰ اﻟﻌﻠوم
اﻟﻌﻠﻤﺎﻨﻴﺔ. ﻛﻤﺎ ﻫو اﻟﺤﺎﻝ ﻟﻛﺜﻴر ﻤن أﺒﻨﺎء طﺒﻘﺔ اﻟﻤﺜﻘﻔﻴن اﻟﻴﻬود ﻓﻲ ﺸرق أورﺒﺎ آﻨذاك ٬ واﻟذﻴن وﺠﻬوا ﻟﺒﺎﺒﻬم
ﻟﻠﻌﻠوم واﻷدب اﻟﺠﻤﻴﻝ اﻟﻌﻠﻤﺎﻨﻲ ﻛﺠزء ﻤن روح اﻟﺤﻴﺎة ﻓﻲ ﺘﻠك اﻟﻔﺘرة. أﻤﻪ إﺴﺘﻴر ﻤن ﺒﻴت زﻟدﻴن ﺘوﻓﻴت
ﻋﻨدﻤﺎ ﺒﻠﻎ ﺸﺎﻟوم ﻋﻠﻴﺨم اﻟﺨﺎﻤﺴﺔ ﻋﺸر ﻤن ﻋﻤرﻩ. وﺒﻌد أن أﻛﻤﻝ د ارﺴﺘﻪ ﻓﻲ اﻟﺜﺎﻨوﻴﺔ ﻋـُرف ﻤن ﺨﻼﻝ
ﺼﻴت واﻟدﻴﻪ ٬ وﻓﻲ ﺴﻨﺔ ١٨٨٠ – ١٨٨٣ ﻋﻤﻝ ﻓﻲ ﺴﻠك اﻟﺘﻌﻠﻴم ﺤﻴث ﻛﺎن ﻤﻌﻠﻤﺎً ﻟﺸﺎﺒﺔ ﺼﻐﻴرة
(ﻛوﻟداﻟﻴف) اﺒﻨﺔ ﺘﺎﺠر ﻏﻨﻲ ٬ وﻓﻲ ﻨﻬﺎﻴﺔ ﺴﻨوات ﺘدرﻴﺴﻪ ﺘزوج اﻟﻤﻌﻠم اﻟﺼﻐﻴر ﻤن اﺒﻨﺔ اﻟﺘﺎﺠر ﻟﻤﺎ اﺤﺘﻠﻪ ﻤن

ﻤﻛﺎﻨﺔ ﻤرﻤوﻗﺔ ﻓﻲ ﻗﻠب أﺒﻴﻬﺎ. وأﺼﺒﺢ ﻟدﻴﻪ ﺨﻤﺴﺔ أوﻻد ﺜﻤرة ذﻟك اﻟزواج.
HUBUNGAN POLA ASUH ORANGTUA DENGAN KECERDASAN EMOSIONAL ANAK PRA SEKOLAH DI PAUD WILAYAH PUSKESMAS SITOPENG KOTA CIREBON
Authors: Nurasih Nurasih , Elfi Elfi 
Published: November 2023

Pola Asuh Orang Tua merupakan salah satu faktor yang berperan dalam perkembangan kecerdasan emosional ana. Kemampuan orang tua dalam mengembangkan pola asuh yang diterapkan pada anak secara tepat dapat mendorong perkembangan kecerdasan emosional anak yang baik (Hidayah, 2013). Penelitian ini bertujuan untuk mengetahuiÂ hubungan pola asuh orang tua terhadap kecerdasan emosional anak usia pra sekolah (3-5 tahun) di PAUD wilayah Puskesmas Sitopeng Kota Cirebon.Desain penelitian ini adalah studi korelasi dengan pendekatan crossectional. Analaisis data secara univariat, bivariat dan multivariat dengan analisis regresi logistik. Pengambilan sampel dilakukan secara nonprobability sampling (proporsi sampling), adapun subjek penelitiannya adalah orang tua dan siswa PAUD di wilayah Puskesmas Sitopeng Kota Cirebon sebanyak 79 orang. Hasil penelitian didapatkan bahwa mayoritas Pola Asuh orang tua dengan type demokratis (53,2%), kecerdasan emosional kategori baik (62,0%), dan status sosial ekonomi di bawah UMR (60,8%). Analisis bivariat didapatkan bahwa tidak ada hubungan antara pola asuh orang tua Â (P value 0,98), dan Status Sosial Ekonomi Â Â (P value 0,71).dengan kecerdasan emosional anak.Kesimpulan dalam penelitian ini adalah tidak terdapat hubungan antara pola asuh orang tua dengan kecerdasan emosionl anak. Diharapkan Puskesmas dapat meningkatkan pembinaan yang selama ini telah dilakukan melalui program pemantauan pertumbuhan dan perkembangan pada anak pra sekolah, sehingga guru dan orang tua dapat melakukan stimulasi yang maksimal untuk mencapai pertumbuhan dan perkembangan anak yang maksimal pula