bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two-step minimization approach to Sobolev-type inequality with inhomogeneous potential in 1D
Authors: Apriliani Vina , Kimura Masato , Ohtsuka Hiroshi 
Published: October 2023

Abstract
We present a new method to determine the best constant of the Sobolev-type embedding in one dimension with a norm including an inhomogeneous potential term. This problem is closely connected to the Green function of the Schr ̈odinger operator with inhomogeneous potential. A minimization problem of a Rayleigh-type quotient in a Sobolev space gives the best constant of the Sobolev embedding. We decompose the minimization problem into two sub-minimization problems and show that the Green function provides the minimizer of the first minimization problem. Then, it enables us to derive a new precise estimate of the best constant and function for inhomogeneous bounded potential cases. As applications, we give some examples of the inhomogeneous potential whose best constant and function of the Sobolev-type embedding are explicitly determined. Furthermore, we consider an Lp- or measure-valued perturbation of the bounded potential and analyze it using a comparison formula and the two-step minimization approach.
Application of a long short-term memory neural network algorithm fused with Kalman filter in UWB indoor positioning
Authors: Tian Yalin , Lian Zengzeng , Wang Penghui , Wang Mengqi , Yue Zhe , Chai Huabin 
Published: October 2023

Abstract
Ultra-wideband technology has good anti-interference capabilities and development prospects in indoor positioning. Since ultra-wideband will be affected by random errors in indoor positioning, to exploit the advantages of the Kalman filter and the LSTM network, this paper proposes a long short-term memory neural network algorithm fused with the Kalman filter (KF-LSTM) to improve UWB positioning. First, the ultra-wideband data is processed through Kalman filtering to weaken the noise in the data, and then the data is fed into the LSTM network for training, and the capability of the LSTM network to process time series features is employed to obtain more accurate label positions. Finally, simulation and measurement results show that the KF-LSTM algorithm achieves 71.31%, 37.28%, and 49.31% higher average positioning accuracy than the BP, KF-BP, and LSTM network algorithms, respectively, and the KF-LSTM algorithm performs more stably. Meanwhile, the more noise the data contains, the more obvious the stability contrast between the four algorithms.
Wormholes and energy conditions in Rastall-Rainbow Gravity
Authors: Banerjee Ayan , Islam Safiqul , Pradhan Anirudh , Zeyauddin M. 
Published: October 2023

Abstract
An interesting class of modified gravity theory has recently been proposed, namely, the Rastall-Rainbow gravity. This theory is a combination of two theories: the Rastall theory and the Rainbow description. The present work is devoted to explore the possibility of the existence of static spherically symmetric wormholes and present the full gravitational field equations. In particular, considering specific choices for the redshift and shape functions, we present exact solutions of asymptotically flat wormhole geometries. With the specific examples, we investigate some issues concerning energy conditions and adiabatic sound velocity. We also consider the “volume integral quantifier” to assess the total amount of energy-condition violating matter. Finally, we conclude that the violation of energy conditions may be alleviated by decreasing Rastall’s parameters and adjusting the Rainbow functions.
TTAFPred: Prediction of time to aging failure for software systems based on a two-stream multi-scale features fusion network
Authors: Jia Kai , Yu Xiao , Zhang Chen , Xie Wenzhi , Zhao Dongdong , Xiang Jianwen 
Published: October 2023

Abstract

Software aging refers to the performance degradation and failure crash phenomena in long-running systems. As a proactive remedy, software rejuvenation can be scheduled timely to mitigate aging effects. Inescapably, how to accurately predict the time to aging failure (TTAF) of software is a prerequisite for implementing effective rejuvenation. However, the characterization of software aging is relatively complicated, leading to the selection of aging indicators case by case, which means that only fitting the variation trend of a single indicator for prediction models to formulate a rejuvenation schedule may be limited. To fill this gap, this paper proposes a novel framework called TTAFPred, which directly constructs the direct mapping relationships between the software aging process considering multiple system indicators and TTAF. Specifically, this framework includes three parts, i.e., data preprocessing, software degradation feature extraction , and TTAF prediction modules. First, the raw data is processed into the input form required by the network. Secondly, a temporal relationship extraction stream integrating bidirectional gated recurrent unit (BiGRU) with attention mechanism is used to extract temporal features from raw inputs. Synchronously, a spatial relationships extraction stream is adopted to extract the spatial features 1 for enhancing the representation ability of degraded features by using the multi-scale one-dimensional convolutional neural network (1DCNN) with the residual connection. Then, extracted temporal-spatial features from the two streams are further fused. Finally, two fully-connected layers are constructed to estimate the TTAF. The experiments are performed on two mainstream software systems (OpenStack and Android), and four sets of real run-to-failure data for each software system are collected. The effectiveness of the proposed TTAFPred is verified through extensive experiments with its seven competing models, and the prediction performance can be improved by 9.1%, 8.0%, and 8.0%, respectively, in terms of three evaluation metrics, compared to the best baseline model.
Effectiveness of defocus lenses in youth vision control Running Title: a meta-analysis
Authors: Chu Hui-Hui , Liu Xue , Zuo Hua-Xin , Yu Ji-Feng 
Published: October 2023

Abstract
Purpose: To systematically evaluate the effectiveness of defocused lenses in the control of adolescent visual acuity. Methods: The Cochrane library, Web of science, PubMed, Proquest and Chinese biomedical literature databases Wanfang, Vipu and CNKI were used to search for relevant literatures on the controlled trial of defocusing lenses in adolescent vision control from self-built databases to June 2023. According to the inclusion and exclusion criteria, 5 studies were selected for meta-analysis. RevMan 5.3 software was used to analyze the included literatures and explore the heterogeneity of each study. Results: 5 controlled trials involving 947 subjects were finally included. meta-analysis showed that defocus lenses slowed the increase in myopic refraction [OR: 0.21, 95CI% (0.09, 0.33), p=0.0008], reduced refraction levels [OR:-0.30, 95CI% (-0.58,-0.01), p=0.04] , reduced axial length [OR: 0.49, 95CI% (0.31, 0.67), P<0.00001], all of the above differences were statistically significant. The funnel plots for each study suggested that the scatter was essentially symmetrical and in to a funnel-shaped distribution, so the funnel plots suggested no publication bias. Conclusion: Defocus lenses used in youth vision control are effective in slowing down the increase in myopic refraction and reducing refraction levels and axial length.
Perforation of the Terminal Ileum Caused by Brucellosis: A Case Report
Authors: wang Chun , Yang Xiaoran , Zhou Jia , Liu Xu , Li Xuzhao 
Published: October 2023

Abstract
Brucellosis is a zoonotic disease caused by infection with gram-negative coccobacilli belonging to the genus Brucella, resulting in invasion of multiple systems and organs. Bone and joint involvement are its most common complication. Acute abdomen with intestinal perforation caused by Brucella infection is very rare. Here we report a case in a 69-year-old man who was diagnosed with acute diffuse peritonitis with hollow organ perforation before surgery. Exploration during the operation revealed intestinal perforation at the end of ileocecum, with wheel spoke-like necrosis at the end of ileum. Partial resection of the necrotic small intestine, closure of the end of ileum and ileostomy were performed. Postoperative blood culture and a Brucella agglutination test were both positive for Brucella. Targeted treatment with tetracycline and aminoglycosides was given. The patient recovered and was discharged.
5G and Beyond Wireless Network Optimization through RIS Technology: A Pricing Game
Authors: Daoudi Lhoussaine , Baslam Mohamed , Zagour Mohamed , Safi Said 
Published: October 2023

Abstract
This paper aims to improve wireless networks beyond 5G by solving problems such as dead zone connections, physical layer security, and high costs with the aid of reconfigurable intelligent surfaces (RISs). Trusted RIS holders could purchase the copyrights of RIS technology from wireless service providers, their competitive behaviors were simulated using a non-cooperative pricing game to optimize the utility of the pricing structure. RIS holders were supposed to be bounded rational and base their decisions on past strategies. This selfish action was framed as a duopoly game of bounded rationality with history. To ensure fairness, the solution to this game was defined as the Nash equilibrium, but maintaining the stability of this solution was difficult. The local stability of the solution was analyzed. Numerical simulations showed that RIS holders who possessed story-awareness were more likely to attain Nash equilibrium, and its stability region became larger for specific story weights and RIS size values. Next, a basin of attraction graph simulated the effect of history on the global stability of Nash equilibrium. The study provided information to RIS holders to minimize the cost of installing RIS on their own or rented properties while transmitting more radio spectrum to users.
Insulator, resister, and conductor are capacitors
Authors: Shang Muyuan 
Published: October 2023

Abstract
The phenomenon of dispersion and absorption in materiel has been interpreted by dielectric polarization for more than a century. A different theory for the phenomenon was constructed after the capacitance had been found in rock. The new theory has approved that an insulator is also with capacitance. The phenomenon of negative dielectric constant in the conductor (metals) is hard to be explained by polarization theory. All the formulas describing the dispersion based on polarization theory is empirical formula and contradicts each other. Here we show that the metal is also with capacitance and the negative dielectric constant is mainly caused by induction. The bottleneck effect for the current causes material capacitance. The capacitance formula of this new theory is same to the different polarization based empirical formulas mathematically. The material capacitance formula can be adopted to insulators, resistors, and conductors. In the previous articles, author has approved that the capacitance formula can be adopted to insulators and resistors. In this article, it mainly has approved that the capacitance formula can be also adopted to conductor. In brief, all material such as insulator, resistor, and conductor are with capacitance. This paper puts the explanation of dispersion from empirical formula forwards the theory conduced formula.
Elastic flow of curves with partial free boundary
Authors: Diana Antonia 
Published: October 2023

Abstract

We consider a curve with boundary points free to move on a line in $\R^2$, which evolves by the $L^2$--gradient flow of the elastic energy, that is a linear combination of the Willmore and the length functional.For such planar evolution problem we study the short and long--time existence. Once we establish under which boundary conditions the PDE's system is well--posed (in our case the Navier boundary conditions), employing the Solonnikov theory for linear parabolic systems in H\"older space, we show that there exists a unique flow in a maximal time interval $[0,T)$. Then, using energy methods we prove that the maximal time is actually $T= + \infty$.
Mathematics Subject Classification (2020): Primary 53E40; 35G31, 35A01.
Speciation of Potentially Toxic Metals from the Mine Impacted soils: A Case Study of Riruwai Mining Area, Kano State, Northern Nigeria
Authors: Badamasi Hamza , Hassan Umar Faruk , Adamu Harami Malgwi , Baba Nasirudeen Mohammed , Adamu Dahiru Ajiya , Baba Haruna 
Published: October 2023

Mining and smelting sectors contribute significantly to global growth on a regional and local scale. However, the operations are causing significant environmental damage, particularly pollution of the soil with potentially toxic metals (PTMs). In this study, the speciation of PTMs (arsenic, cadmium, chromium, mercury, manganese, nickel, lead and zinc) from the mine impacted soils of Riruwai mining area was investigated using a modified Tessier sequential extraction method. The findings of the study revealed that all the PTMs examined are considerably associated with non-residual fractions in all the sampling locations. This indicates that all the PTMs investigated in the study area may be highly mobile in the soils and hence potentially toxic. The concentrations of PTMs in the soil’s geochemical fractions were found to vary with the sampling locations, with active mining sites significantly (p ≤ 0.05) recording the highest value, followed by farmland, while the lowest value was reported at the control site. Therefore, to protect the environment and the health of the local populace, PTMs in the soils of the study area should be regularly monitored and a treatment program should be put in place.
Is Adrenaline Always the First Choice Therapy of Anaphylaxis? An
Allergist-cardiologist Interdisciplinary Point of View
Authors: Calogiuri Gianfranco , Savage Michael P. , Congedo Maurizio , Nettis Eustachio , Mirizzi Alessandro Mandurino , Foti Caterina , Vacca Angelo , Kounis Nicholas G. 
Published: October 2023

Abstract:
Worldwide, adrenaline is considered the first choice therapy in the international guidelines for the
management of anaphylaxis. However, the heart and cardiovascular apparatus are strongly involved in anaphylaxis;
for that reason, there are some cardiac conditions and certain anaphylaxis patterns that make epinephrine
use problematic without adequate heart monitoring. The onset of Kounis syndrome, takotsubo cardiopathy, or
the paradoxical anaphylaxis require great attention in the management of anaphylaxis and adrenaline administration
by clinicians, who should be aware of the undervalued evolution of anaphylaxis and the potential cardiologic
complications of epinephrine administration. Numerous case reports and studies describe the unexpected
onset of cardiac diseases following epinephrine treatment, despite the latter being the recommended therapy
for anaphylaxis. Our review suggests that future anaphylaxis guidelines should incorporate cardiovascular specialists
since the treatment of Kounis syndrome or takotsubo cardiopathy requires cardiologist skills.
A Review on Traditional and Modern Methods for the Synthesis of Aromatic Azo
Compounds
Authors: Patel Ashok Raj , Patel Geetika , Srivastava Arti , Banerjee Subhash 
Published: October 2023

Abstract:
Aromatic azo compounds are “derivatives of diazene/diimide”, wherein the two hydrogens are substituted by phenyl groups. Azo compounds are very important universal scaffolds that show multiple applications
in many areas of science, mainly chemical industries, where they are used in the synthesis of organic dyes, pigments, food additives, indicators, etc. They also remarkably exhibit various potential applications in the fields of
pharmaceuticals, electronics, optics, etc., because of their fascinating photophysical properties. Moreover, several azo compounds have been strongly utilized as chemosensors, diagnostic probes, radical initiators, nanotubes,
and building blocks of various polymers as well as natural products. This interesting and immense importance of
the azo compounds has attracted the attention of researchers to establish novel synthetic routes to synthesize
these important scaffolds. In organic chemistry, azo compounds can be synthesized by various methods utilizing
coupling reactions with the aid of a catalyst or sometimes in the absence of it. The main purpose of writing this
review was to provide a summary of the synthesis of both symmetric and asymmetric azobenzenes via various
traditional and recently developed oxidative aza-coupling reactions.
Dimeric Calix[4]arenes, Synthesis and their Application: A Review
Authors: Zadmard Reza , Khosravani Sara , Jalali Mohammad Reza 
Published: October 2023

Abstract:
Calix[n]arene is an attractive host for molecular recognition due to its accessibility through the hollow cavity and shallow bowl shape and has been used as a receptor over the last 30 years. Calix[n]arene has a
small cavity, so designing a flexible molecule to recognize nano to large biomolecules is a challenging goal in
host-guest chemistry. Dimeric calix[n]arene is formed by linking two calix[n]arene sub-units to each other.
Their considerable structural features and relative diversity of modifying the upper or lower rim represent outstanding and greatly adaptive structures for designing bulky and complex building blocks adequate for selfassembly and molecular recognition. Their ability to form supramolecular structures for a wide range of applications, including the recognition of nano-molecules and large biological molecules, has been extensively studied. This review details the progress of the host-guest chemistry of dimeric calix[n]arenes, emphasizing the synthetic pathways employed for their production and their self-assembly properties. Dimerization of calix[n]arene
occurs in two ways (1-through non-covalent bonding such as H-bonding or self-assembly, and 2-through covalent bond formation such as amide bond formation, multi-component reactions and Sonogashira cross-coupling
reaction and metathesis reactions). In this work, we focused on dimerization through covalent bond formation,
due to having more applications and diverse synthetic applications.
High Prevalence of a c.5979dupA Variant in the Dysferlin Gene (DYSF) in
Individuals from a Semiarid Region of Brazil
Authors: Motta Isabella A. , Gouveia Maria L.A. , Braga Ana P.M. , Andrade Rafael S. , Montenegro Mayra F.F. , Gurgel Sandra N. , Albuquerque Keila M.F. , Souto Priscilla A.N.G. , Cardoso Flávia P.B.F. , Araujo Joseane S. , Pinheiro Mirella C.L. , da Silva Carlos E.P. , Gurgel Pamella A.S. , Feder David , Perez Matheus M. , da Veiga Glaucia L. , Alves Beatriz C.A. , Fonseca Fernando L.A. , Carvalho Alzira A.S. 
Published: October 2023

Background:
Dysferlinopathies represent a group of limb girdle or distal muscular dystrophies with an autosomal-recessive inheritance pattern resulting from the presence of pathogenic
variants in the dysferlin gene (DYSF).

Objective:
In this work, we describe a population from a small city in Brazil carrying the
c.5979dupA pathogenic variant of DYSF responsible for limb girdle muscular dystrophy type 2R
and distal muscular dystrophy.

Methods:
Genotyping analyses were performed by qPCR using customized probe complementary
to the region with the duplication under analysis in the DYSF.

Results:
A total of 104 individuals were examined. c.5979dupA was identified in 48 (46.15%) individuals.
Twenty-three (22%) were homozygotes, among whom 13 (56.5%) were female. A total of
91.3% (21) of homozygous individuals had a positive family history, and seven (30.4%) reported
consanguineous marriages. Twenty-five (24%) individuals were heterozygous (25.8±16 years) for
the same variant, among whom 15 (60%) were female. The mean CK level was 697 IU for homozygotes,
140.5 IU for heterozygotes and 176 IU for wild-type homo-zygotes. The weakness distribution
pattern showed 17.3% of individuals with a proximal pattern, 13% with a distal pattern and
69.6% with a mixed pattern. Fatigue was present in 15 homozygotes and one heterozygote.

Conclusion:
The high prevalence of this variant in individuals from this small community can be
explained by a possible founder effect associated with historical, geographical and cultural aspects.
Polypyrimidine Tract Binding Protein: A Universal Player in Cancer Development
Authors: Gonzalez Elizabeth , Flatt Terrie G. , Farooqi Midhat , Johnson Lisa , Ahmed Atif A. 
Published: October 2023

Objectives:
Polypyrimidine tract binding protein is a 57-Kda protein located
in the perinucleolar compartment where it binds RNA and regulates several biological
functions through the regulation of RNA splicing. Numerous research articles have
been published that address the cellular network and functions of PTB and its isoforms
in various disease states

Methodology:
Through an extensive PubMed search, we attempt to summarize the
relevant research into this biomolecule.

Results:
Besides its roles in embryonic development, neuronal cell growth, RNA
metabolism, apoptosis, and hematopoiesis, PTB can affect cancer growth via several
metabolic, proliferative, and structural mechanisms. PTB overexpression has been
documented in several cancers where it plays a role as a novel prognostic factor.

Conclusion:
The diverse carcinogenic effect opens an argument into its potential role
in inhibitory targeted therapy.
Pharmacological Potential of Sulindac and Its Active Metabolite: A
Comprehensive Review
Authors: Gupta Shraddha Manish , Behera Ashok , Singh Siddharth 
Published: October 2023

:
In this review, we describe and discuss the pharmaceutical aspects, pharmacokinetic profile,
and preclinical and clinical studies of sulindac and its active metabolite and emphasise their
potential activity not only in anti-inflammation strategies but also as chemoprevention drug candidates.
Though they are widely validated through in vitro and in vivo models, to date, no efforts have
been made to compile in a single review on their pharmacologically potential, pharmacokinetics and
toxicity profiles. Key databases such as PubMed, Science Direct, Scopus, and Google Scholar, among
others, were probed for a systematic search using keywords to retrieve relevant publications. An exhaustive
electronic survey of the related literature on the pharmacologically potential activity and the
pharmacokinetic and toxicity profiles of sulindac resulted in around 200 articles (1975 and 2023)
being included. The studies conducted on sulindac sulphide and sulindac sulfone metabolites reported
a varied range of biological effects deployed in this review. The review concluded that there is scope
for repurposing sulindac using computer-aided drug design and biological study to find out possible
new targets for strengthening the potency and selectivity of the metabolites.