bluuebunny/crossref_metadata_2025_split huggingface dataset:
Reconstruction with the right gastroepiploic vein during pancreaticoduodenectomy and total pancreatectomy to prevent left-sided portal hypertension: a report of two cases
Authors: Hatai Sanshiro , Kaku Keizo , Kubo Shinsuke , Sato Yu , Noguchi Hiroshi , Okabe Yasuhiro , Ikenaga Naoki , Nakata Kohei , Nakamura Masafumi 
Published: November 2023

Abstract
Background
Left-sided portal hypertension including gastric venous congestion may be caused by ligating the splenic vein during pancreaticoduodenectomy with portal vein resection or total pancreatectomy. The usefulness of reconstruction with the splenic vein has been reported in such cases. However, depending on the site of the tumor and other factors, it may be impossible to leave sufficient length of the splenic vein, making anastomosis difficult. We report two patterns of reconstruction with the right gastroepiploic vein during pancreaticoduodenectomy and total pancreatectomy to prevent left-sided portal hypertension.

Case presentation
The first patient was a 79-year-old man who underwent pancreaticoduodenectomy for pancreatic cancer. The root of the splenic vein was infiltrated by the tumor, and we resected this vein at the confluence of the portal vein. Closure of the portal vein was performed without reconstruction of the splenic vein. To prevent left-sided portal hypertension, we anastomosed the right gastroepiploic vein to the middle colic vein. Postoperatively, there was no suggestion of left-sided portal hypertension, such as splenomegaly, varices, and thrombocytosis. The second case was a 63-year-old woman who underwent total pancreatectomy for pancreatic cancer. The splenic vein–superior mesenteric vein confluence was infiltrated by the tumor, and we resected the portal vein, including the confluence. End-to-end anastomosis was performed without reconstruction of the splenic vein. We also divided the left gastric vein, left gastroepiploic vein, right gastroepiploic vein, and right gastric vein, which resulted in a lack of drainage veins from the stomach and severe gastric vein congestion. We anastomosed the right gastroepiploic vein to the left renal vein, which improved the gastric vein congestion. Postoperatively, imaging confirmed short-term patency of the anastomosis site. Although the patient died because of tumor progression 8 months after the surgery, no findings suggested left-sided portal hypertension, such as varices. Reconstruction with the right gastroepiploic vein during pancreaticoduodenectomy and total pancreatectomy is useful to prevent left-sided portal hypertension.
Phytochemistry, efficacy, and safety of medicinal plants used traditionally for the management of peptic ulcer diseases in Ethiopia: a systematic review
Authors: Mustefa Abdulkerim , Nardos Aschalew , Hailu Dejene , Deyno Serawit 
Published: November 2023

Abstract
Background
Despite significant advances in synthetic medicine, medicinal plants are still widely utilized to treat peptic ulcer disease. This study synthesized evidence on commonly used medicinal plants to manage peptic ulcer disease in Ethiopia.

Methods
The evidence was synthesized using electronic databases such as PubMed/Medline, Web of Science, Science Direct, Hinari, and Google Scholar. This review considers all controlled in vivo and ex vivo anti-ulcer studies evaluating Ethiopian medicinal plants with regards to phytochemistry, efficacy, and safety. The search technique covered all published papers using descriptors like Ethiopia, medicinal plants, and anti-ulcer until January 30, 2022. The percentage of ulcer reduction was used to measure the success of the treatment.

Results
Anti-ulcer properties were investigated in 13 papers. Twelve in vivo and one ex vivo study were retrieved. Osyris quadripartita, Plantago lanceolata, Ensete ventricosum, Taverniera abyssinicia, Crotonmacrostachyus Persea Americana and Moringa stenopetala showed effect close to a standard control in difference ulcer induced model. Osyris quadripartite in the dose of 200 mg/kg, Ficus thonningii in dose of 200 and 400 mg/kg, Plantago lanceolata in dose of 400 mg/kg, Trigonella feonum-gracum in dose of 500 and 1000 mg/kg, Linum ussitatissimum in dose of 1000 and 1500 mg/kg, Urtica simensis 400 mg/kg have higher activity compared with standard control in difference different models. Phytochemistry studies revealed presence of numerous components, including flavonoids, phenols, tannins, and saponins, which may be responsible for the anti-ulcer activity.

Conclusion
This study revealed that there are some promising medicinal plant extracts that have been used in Ethiopia for centuries that could be used as anti-ulcer agents. The most effective anti-ulcer agents in animal models are Indigofera spicata Forssk, Thymus schimperi, and Urtica simensis. Identification of most active pharmacological agents and clinical evaluation of Ethiopian medicinal plants used to treat peptic ulcers are worthy of further investigation.
Predictive value of the anterior communicating artery (ACoA) complex variations for the incidence and rupture of ACoA aneurysms
Authors: Hassanin Bahaa Ghareeb , Abdelhameid Ahmed Kamal , Abbas Mohamed Abdala , Mohamed Reham Bakry , Schebesch Karl-Michael 
Published: November 2023

AbstractBackgroundIncrease pressure on arteries branching points and curves (hyperdynamic theory) is the most popular theory to explain the aneurysms formation that augmented by the observation of high incidence of anomalies (either A1 aplasia or hypoplasia) and the anterior communicating artery (ACoA) aneurysms. It still underestimated the correlation between these anatomical anomalies and aneurysm occurrence and its rupture. We aim to estimate the incidence and type of anatomical anomalies of the anterior cerebral circulation, including the A2 segment in patients with ACoA aneurysms and their predictive value for aneurysm occurrence and rupture parallel to the risk of hypertension. Also, we study the impact of these anomalies on the configuration of the aneurysm, including the neck and size.ResultsA1 hypoplasia and aplasia were significantly higher in AcoA aneurysms group than in the control group (P < 0.001 and 0.002, respectively). These anomalies have no significant statistical difference between rupture and unruptured ACoA aneurysms. A2 anomalies were insignificantly different between both groups.ConclusionCongenital anomalies in the A1 segment (hypoplasia and aplasia) have a significant predictive value for AcoA aneurysms formation, with no predictive value for the aneurysm rupture. Concomitantly, A2 anomalies have no significant risk for AcoA aneurysms formation and rupture.
Investigating the prevalence of cervical spine instability in patients with rheumatoid arthritis
Authors: Rezakhah Amir , Kobets Andrew J. , Emami Sigaroudi Faezeh , Habibi Mohammad Amin , Derakhshesh Rahim , Javanshir Rezaei Naghmeh , Naseri Alavi Seyed Ahmad 
Published: November 2023

Abstract
Introduction
Rheumatoid arthritis (RA) is a chronic, progressive, and systemic disease that broadly affects connective tissues, especially synovial joints. The aim of this study was to investigate the prevalence of cervical spine instability in patients diagnosed with RA.

Material and methods
Fifty patients with rheumatoid arthritis referred to Imam Khomeini Hospital in Urmia were selected by the census. After taking a history, the neck X-ray was taken from the lateral view in static, flexion, and extension.

Results
Among 50 patients, 11 were male (22%) and 39 were female (78%). The average disease duration period was 5.63 ± 5.21 years. 43 patients (86%) had normal AADI, 5 patients (10%) had abnormal dynamic AADI, and 2 patients (4%) had abnormal AADI static. Basilar invagination instability was not found in the studied patients. There was no significant difference in terms of gender between normal and abnormal cases of AADI. Among normal AADI cases, 40 cases (93%) were taking drugs and among abnormal AADI cases, 4 cases (57.1%) were taking drugs and 3 patients (42.9%) were not receiving drug treatment. There is a significant difference between normal and abnormal cases of AADI in terms of drug use.

Conclusions
In our study, 7 cases of abnormal AADI were found among 50 patients, of which 2 had abnormal static AADI, which indicates the worsening of cervical spine instability. The study also found that those not treated with DMARDS were more likely to have cervical spine instability.
A look back at the prodromal findings in Parkinson’s disease
Authors: Ahadiat Seyed-Amirabbas , Hosseinian Zeinab 
Published: November 2023

Abstract
Background
Parkinson's disorder is a neurodegenerative illness that displays motor and non-motor manifestations. There is no definite cause of Parkinson's disorder, nor is there a medicine or treatment to prevent it.

Main body of the abstract
Non-motor manifestations of the disorder are referred to be progressive symptoms of the disorder by medical specialists since they might emerge chronically several years before motor symptoms. Among these symptoms are a loss of smell, constipation, a sleep disorder, melancholy, sexual dysfunction, and depression. In this paper, we focus on several different aspects related to Parkinson's disorder (PD) prodromal features and their prevalence in PD patients, pathophysiology, treatment (if possible), and the impact of prodromal symptoms on diagnosis, prognosis of life of patients.

Short conclusion
All people who present with these non motor prodermal symptoms should be considered by specialists for further tests for early diagnosis of this disease.
On considering Australia: exploring Indonesian restaurants in promoting ethnic foods as an instrument of Indonesian gastrodiplomacy
Authors: Yayusman Meilinda Sari , Yaumidin Umi Karomah , Mulyasari Prima Nurahmi 
Published: November 2023

AbstractFood is said to be ethnic, when it comes from diverse regions that have crossed international borders. Ethnic food has the ability to contribute to the growth, promotion, and strengthening of intercultural connections. Recently, Indonesia has launched a gastrodiplomacy strategy, named ‘Indonesia Spice Up the World’ (ISUTW). ISUTW aims to increase spice exports to USD 2 billion by 2024 and present Indonesian ethnic foods toward the establishment of 4,000 Indonesian restaurants abroad. Australia as one of the closest neighbor countries is considered to be a strategic target nation. This study serves a dual purpose: first, to investigate the state of culinary traditions embraced by the Indonesian business owners working in culinary business in Australia and, second, to recognize the role of Indonesian diasporas, including students, who also partake in introducing distinctive Indonesian ethnic foods to both native Australians and fellow Indonesian residents in Australia. In this study, a mixed-methods approach was employed, which encompassed surveys, literature reviews, and focus group discussions. The findings of this study, such as Indonesian culinary business patterns and consumer behaviors in Australia, offer recommendations for the governments of Indonesia and Australia to maintain favorable diplomatic relations by means of promoting Indonesian ethnic foods, in this context called as gastrodiplomacy attempts.
Predictors of persistent asthma among preschooler wheezers: a retrospective case series study
Authors: Barakizou Hager 
Published: November 2023

Abstract
Background
Early childhood wheezing can evolve to different asthma phenotypes. Prediction of persistent asthma during the preschool years has proven challenging. Through this study, we aimed to identify predictors of persistent asthma in preschooler wheezers.

Methods
This was a retrospective case series study over 10 years. Patient data from 98 infants diagnosed with infantile asthma were obtained from their medical records. A multivariate logistic regression model was developed to determine predictors of persistent asthma in preschooler wheezers.

Results
The sex ratio was 1.72. The mean age at the first episode of wheezing was 7 ± 3.17 months. The mean age at diagnosis was 14.82 ± 4.28. Asthma was well controlled in 71 cases (72.44%) and partly controlled in 27 cases (27.56%). Two groups were identified: transient wheezers (61.33%) and persistent wheezers beyond the age of 5 years old (38.77%). The average age for wheezing disappearance was 24.28 ± 4.1 months.
Four predictive factors for persistent asthma were identified: familial atopy (adjusted odds ratio [OR] 4.76; 95% confidence interval [CI] 2.52–12.45; p < 0.001), passive smoking (adjusted OR 5.98; 95% CI 2.48–13.64; p < 0.001), poor control of asthma (adjusted OR 5.23; 95% CI 2.47–14.76; p 0.0013), and aerosensitization (adjusted OR 7.38; 95%CI 3.87–17.84; p < 0.001).

Conclusions
The main predictors for persistent asthma among preschooler wheezers were aerosensitization, family history of atopy, early exposure to passive smoking, and poor control of asthma. The detection of such factors allows for earlier diagnosis and targeted prevention strategies.
Impact of rest time on creep recovery of asphalt mixtures modified with calcined marl filler
Authors: Usanga Idorenyin Ndarake , Okafor Fidelis Onyebuchi , Ikeagwuani Chijioke Christopher 
Published: November 2023

AbstractRecently, there has been a trend among pavement engineers and scientists to utilize natural mineral resources found in different parts of the world to develop and enhance sustainable infrastructure. One of such materials is calcined clay. However, the fatigue performance of asphalt mixtures made with these alternative materials needs to be properly studied. Due to its complex composition, asphalt concrete exhibits diverse non-linear characteristics when subjected to different conditions. As such, the impact of rest time, considering the effect of hardening relaxation and healing on the creep recovery of asphalt mixtures modified with calcined marl filler (CMF), has been evaluated in this present study. Thus, the locally sourced marl was pulverized and calcined to produce CMF. Different amounts of CMF were added to asphalt mixtures as a mineral filler, ranging from 0% to 100% by weight. Afterwards, the rheological properties of CMF mastic using a dynamic shear rheometer (DSR) were investigated. Notably, the outcomes of the experiments revealed compelling insights. Specifically, under the influence of 50% CMF modification, the asphalt mixtures exhibited a remarkable rutting resistance, with values reaching 12.7 kPa for unaged conditions and 16.1 kPa for aged conditions. Additionally, the results underscored an enhancement in the low-temperature characteristics of the bitumen mastic, which consequently contributed to heightened resistance against fatigue-induced damage. Furthermore, the statistical analysis, such as the student t-test, deployed to compare the creep recovery with and without rest time indicated that the creep recovery changes with the application of rest time. Hence, at long rest times, the hardening relaxation behavior reduces and the chances of healing increase, leading to a decrease in the amount of deformation in the samples.
Object detection using convolutional neural networks and transformer-based models: a review
Authors: Shah Shrishti , Tembhurne Jitendra 
Published: November 2023

AbstractTransformer models are evolving rapidly in standard natural language processing tasks; however, their application is drastically proliferating in computer vision (CV) as well. Transformers are either replacing convolution networks or being used in conjunction with them. This paper aims to differentiate the design of convolutional neural networks (CNNs) built models and models based on transformer, particularly in the domain of object detection. CNNs are designed to capture local spatial patterns through convolutional layers, which is well suited for tasks that involve understanding visual hierarchies and features. However, transformers bring a new paradigm to CV by leveraging self-attention mechanisms, which allows to capture both local and global context in images. Here, we target the various aspects such as basic level of understanding, comparative study, application of attention model, and highlighting tremendous growth along with delivering efficiency are presented effectively for object detection task. The main emphasis of this work is to offer basic understanding of architectures for object detection task and motivates to adopt the same in computer vision tasks. In addition, this paper highlights the evolution of transformer-based models in object detection and their growing importance in the field of computer vision, we also identified the open research direction in the same field.
Sublethal concentrations of thiamethoxam induce transgenerational hormesis in cotton aphid, Aphis gossypii Glover
Authors: Gul Hina , Güncan Ali , Ullah Farman , Ning Xinyuan , Desneux Nicolas , Liu Xiaoxia 
Published: November 2023

AbstractIn agroecosystems, insects have to compete with chemical insecticides, which are frequently present at sublethal concentrations. The exposure of insects to these modest stresses is now well-established to generate hormesis effects, which has implications for controlling insect pests. In this study, we assessed the sublethal effects of thiamethoxam on the biological parameters of Aphis gossypii Glover (Hemiptera: Aphididae), adults (F0) and subsequent transgenerational impacts, i.e., on the progeny (F1 generation), using an age stage, two-sex life table analysis. Results showed that thiamethoxam exhibited high toxicity against adult A. gossypii with the LC50 of 0.313 mg L−1 after 48 h exposure. The LC5 and LC10 of thiamethoxam considerably reduced the adult cotton aphids (F0) longevity and fecundity, while the reproductive days were reduced only at LC10. The pre-adult stage was decreased, while the adult longevity, total longevity, and fecundity were significantly extended in F1 aphids after exposure of F0 aphids to the sublethal concentrations of thiamethoxam. Moreover, the key demographic parameters such as intrinsic rate of increase, finite rate of increase and reproductive days were significantly increased, while mean generation time and total prereproductive were significantly reduced in the progeny. No significant effects were observed on the net reproductive rate. Taken together, these results showed that the sublethal concentrations of thiamethoxam affect the directly exposed aphids (F0) while causing transgenerational hormetic effects on the F1 generation of A. gossypii. In conclusion, our research showed that thiamethoxam has both sublethal and transgenerational effects on cotton aphids; it could be effective in IPM programs targeting this key pest.
Suicidal ideation across depressive episodes: 9-year longitudinal cohort study
Authors: Kivelä Liia M. M. , Antypa Niki , Fried Eiko I. , Schoevers Robert , van Hemert Albert M. , Penninx Brenda W. J. H. , van der Does A. J. Willem 
Published: November 2023

Background
Depression is a highly recurrent disorder, with more than 50% of those affected experiencing a subsequent episode. Although there is relatively little stability in symptoms across episodes, some evidence indicates that suicidal ideation may be an exception. However, these findings warrant replication, especially over longer periods and across multiple episodes.

Aims
To assess the relative stability of suicidal ideation in comparison with other non-core depressive symptoms across episodes.

Method
We examined 490 individuals with current major depressive disorder (MDD) at baseline and at least one subsequent episode during 9-year follow-up within the Netherlands Study of Depression and Anxiety (NESDA). The Inventory of Depressive Symptomatology (IDS) was used to assess DSM-5 non-core MDD symptoms (fatigue, appetite/weight change, sleep disturbance, psychomotor disturbance, concentration difficulties, worthlessness/guilt, suicidal ideation) at baseline and 2-, 4-, 6- and 9-year follow-up. We examined consistency in symptom presentation (i.e. whether the symptom met the diagnostic threshold, based on a binary categorisation of the IDS) using kappa (κ) and percentage agreement, and stability in symptom severity using Spearman correlation, based on the continuous IDS scores.

Results
Out of all non-core depressive symptoms, insomnia appeared the most stable across episodes (r = 0.55–0.69, κ = 0.31–0.47) and weight decrease the least stable (r = 0.03–0.33, κ = 0.06–0.19). For suicidal ideation, correlations across episodes ranged from r = 0.36 to r = 0.55 and consistency ranged from κ = 0.28 to κ = 0.49.

Conclusions
Suicidal ideation is moderately stable in recurrent depression over 9 years. Contrary to prior reports, however, it does not exhibit substantially more stability than most other non-core symptoms of depression.
The Association of Prenatal Vitamin D Status With Pregnancy and Neonatal Outcomes
Authors: Mao Di , Yuen Lai-Yuk , Ho Chung-Shun , Wang Chi-Chiu , Tam Claudia Ha-Ting , Chan Michael Ho-Ming , Lowe William L , Ma Ronald Ching-Wan , Tam Wing-Hung 
Published: November 2023

Abstract

Context
Vitamin D inadequacy is globally prevalent among pregnant women; however, its impact on pregnancy remains inconclusive.

Objective
This study aims to explore the associations of maternal and umbilical cord serum 25-hydroxyvitamin D (25(OH)D) levels with pregnancy and neonatal outcomes.

Method
We used archived serum samples from the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) Study participants in the Hong Kong center and assayed maternal 25(OH)D levels at midgestation and umbilical cord 25(OH)D at birth using liquid chromatography–tandem mass spectroscopy. Data regarding pregnancy and perinatal outcomes were extracted from the HAPO study dataset and the hospital computerized medical system.

Results
Only 247 (16.4%) mothers and 66 (5.0%) neonates met the criteria for vitamin D sufficiency (ie, 25(OH)D ≥ 75 nmol/L). The ratio of umbilical cord to maternal vitamin D levels was positively associated with maternal age and ambient solar radiation at the month of delivery, while negatively associated with maternal serum total 25(OH)D at midgestation (all P &lt; .001). Umbilical cord serum 25(OH)D was independently associated with a lower primary cesarean section rate (OR 0.990, 95% CI 0.982-0.999; P = .032). There were no associations of maternal and umbilical cord 25(OH)D levels with other adverse pregnancy and neonatal outcomes.

Conclusion
Placental vitamin D transfer was found to be higher with a lower maternal vitamin D level, older maternal age, and higher ambient solar radiation at the time of the delivery. The protective effect of sufficient vitamin D in a cesarean section will require further studies.