bluuebunny/crossref_metadata_2025_split huggingface dataset:
Physical Characterization of Moon Impactor WE0913A
Authors: Campbell Tanner , Battle Adam , Gray Bill , Chesley Steven R. , Farnocchia Davide , Pearson Neil , Halferty Grace , Reddy Vishnu , Furfaro Roberto 
Published: November 2023

Abstract
On 2022 March 4, the object known as WE0913A crashed into the Moon after several close flybys of the Earth and the Moon in the previous three months. Leading up to impact, the identity of the lunar impactor was up for debate, with two possibilities: the Falcon 9 from the DSCOVR mission or the Long March 3C from the Chang’e 5-T1 mission. In this paper, we present a trajectory and spectroscopic analysis using ground-based telescope observations to show conclusively that WE0913A is the Long March 3C rocket body (R/B) from the Chang’e 5-T1 mission. Analysis of photometric light curves collected before impact give a spin period of 185.221 ± 6.540 s before the first close Earth flyby on 2022 January 20 and a period of 177.754 ± 0.779 s, both at a 1σ confidence level, before the second close Earth flyby on 2022 February 8. Using Markov Chain Monte Carlo sampling and a predictive light curve simulation based on an anisotropic Phong reflection model, we estimate both physical and dynamical properties of the Chang’e 5-T1 R/B at the start of an observation epoch. The results from the Bayesian analysis imply that there may have been additional mass on the front of the rocket body. Using our predicted impact location, the Lunar Reconnaissance Orbiter was able to image the crater site approximately 7.5 km from the prediction. Comparing the pre- and post-impact images of the location shows two distinct craters that were made, supporting the hypothesis that there was additional mass on the rocket body.
First report of Diomus guilavoguii Duverger, 1994 (Coleoptera, Coccinellidae, Diomini) predating on papaya mealybug Paracoccus marginatus from China
Authors: Zhuang Jiamin , Huo Lizhi , Tang Mingjie , Xie Xiufeng , Chen Xiaosheng 
Published: November 2023

Diomus guilavoguii Duverger, 1994, an adventive species, is recorded from Guangzhou (Guangdong Province), China for the first time. Larvae of D. guilavoguii were collected in association with an invasive mealybug, Paracoccus marginatus Williams & Granara de Willink, 1992, infesting papayas, cassava and several ornamental plants. However, little has been known about the biology of D. guilavoguii, especially the morphology of their larvae since their original descriptions.
Diomus guilavoguii Duverger, 1994, native to Conakry, Guinea (Africa), is recorded as established in Guangdong Province for the first time. However, it is unclear when and how D. guilavoguii spread from Africa to Guangzhou, Guangdong Province. Both the adult and larva feed on the invasive mealybug Paracoccus marginatus Williams & Granara de Willink (Hemiptera, Pseudococcidae) that infests papaya and ornamental plants. In this paper, the external morphology and male genitalia of adults are re-described. The detailed descriptions of larva and pupa are also provided for the first time. The status of D. guilavoguii and D. hennessyi Fürsch, 1987 are discussed.
Use of artificial stones in training and laboratory studies, have we found the right material? Outcomes of a systematic review from the European School of Urology
Authors: Kallidonis Panagiotis , Peteinaris Angelis , Veneziano Domenico , Pietropaolo Amelia , Pagonis Konstantinos , Adamou Constantinos , Vagionis Athanasios , Al-Aown Abdulrahman , Liatsikos Evangelos , Somani Bhaskar 
Published: November 2023

Objective:
In this review, we investigated the current literature to find out which artificial stones (AS) are available in endourology, and in which experimental and training schemes they are used.

Materials and Methods:
A systematic review was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Twenty-one out of 346 studies met our inclusion criteria and are presented in the current review. The inclusion criteria were the existence of AS and their use for laboratory and training studies.

Results:
There is a wide variety of materials used for the creation of AS. BegoStone powder (BEGO USA, Lincoln, Rhode Island) and plaster of Paris™ were used in most of the studies. In addition, Ultracal-30 (U. S. Gypsum, Chicago, IL) was also used. Other materials that were used as phantoms were AS created from plaster (Limbs and Things, UK), standardized artificial polygonal stone material (Chaton 1028, PP13, Jet 280; Swarovski), model stones consisting of spheres of activated aluminum (BASF SE, Ludwigshafen am Rhein, Deutschland), Orthoprint (Zhermack, Badia Polesine, Italy), and a combination of plaster of Paris, Portland cement, and Velmix (calcium sulfate powder). Many experimental settings have been conducted with the use of AS. Our research demonstrated nine studies regarding testing and comparison of holmium: yttrium–aluminum–garnet laser devices, techniques, and settings. Six studies were about extracorporeal shock wave lithotripsy testing and settings. Three experiments looked into treatment with percutaneous nephrolithotomy. Additionally, one study each investigated imaging perioperatively for endourological interventions, stone bacterial burden, and obstructive uropathy.

Conclusion:
AS have been used in a plethora of laboratory experimental studies. Independent of their similarity to real urinary tract stones, they present a tremendous potential for testing and training for endourological interventions.
Techniques in minimally invasive transperitoneal pyeloplasty: A compilation
Authors: Mallikarjuna Chiruvella , Ghouse Syed Mohammed , Madduri Vijay Kumar Sarma , Bendigeri Mohammed Taif , Enganti Bhavatej , Reddy Purnachandra , Tak Gopal Ramdas 
Published: November 2023

Context:
Minimally invasive management (laparoscopic/robot assisted) is currently the standard of care for managing pelvi ureteric junction obstruction (PUJO). Open techniques of management of PUJO are well described in literature. However, there appears to be relative lack of description of minimally invasive techniques in the literature.

Objective:
This article is aimed at describing in detail, with images, the various techniques and modifications in laparoscopic or robot-assisted management of PUJO.

Evidence Acquisition:
A review of literature on PubMed was performed and all articles which detailed any technique of minimally invasive pyeloplasty were included.

Evidence Synthesis:
The various techniques of minimally invasive pyeloplasty as well as the authors’ techniques are compiled and described in detail with intraoperative images.

Conclusions:
Operative techniques of minimally invasive pyeloplasty are not well described in literature. We have attempted to present a comprehensive resource of different techniques of minimally invasive pyeloplasty and the clinical scenarios in which they may be appropriate. This should prove to be a useful reference to the practicing urologist.

Patient Summary:
In this paper, we have compiled the various surgical techniques of treating obstruction at the PUJ of the kidney along with intraoperative photograph.
Hematuria: Is it useful in predicting renal or ureteral stones in patient presenting to emergency department with flank pain?
Authors: Alnazari Mansour , Bakhsh Abdulaziz , Shaqroon Hatem Ahmed , Rajih Emad S. , Al-Nakshabandi Nizar Abdulaziz , Rabah Danny M. 
Published: November 2023

Abstract

Objectives:
The objective of the study was to evaluate hematuria as a diagnostic test for renal and ureteral stones compared with a noncontrast-enhanced computed tomography (CT) scan (gold standard test) in emergency room patients with acute flank pain.

Patients and Methods:
In total, 604 patients treated in our emergency department from 2006 to 2011, with a history of flank pain and suspected urolithiasis were included in a retrospective review. All patients were evaluated with a noncontrast-enhanced CT scan and urine analysis. Using the noncontrast CT scan as the gold standard for the evaluation of the presence, number, size, and site (renal or ureteral [upper, middle, and lower]) of the stones, we calculated the sensitivity, specificity, and positive and negative predictive values of hematuria for diagnosing both renal and ureteral stones.

Results:
Urolithiasis was diagnosed in 388 patients (64%) and 216 patients (36%) had no stones on a noncontrast-enhanced CT scan. The sensitivity, specificity, positive predictive value, and negative predictive value for microhematuria were 77%, 33%, 67%, and 45%, respectively. Microhematuria was more common in patients with ureteral stones only (139 patients) and had a sensitivity of 85% compared to patients with renal stones only (32 patients), with a sensitivity of 55% (P < 0.001). There were no significant differences in the specificity or positive or negative predictive values.

Conclusion:
Although microhematuria is more sensitive to ureteral stones, the absence of microhematuria does not exclude the possibility of urolithiasis and a noncontrast-enhanced CT scan should be the gold standard diagnostic tool.
Serosurvey for H5, H7 and H9 avian influenza viruses in local chickens in live bird markets within Kaduna metropolis, Nigeria
Authors: Bakam J.D. , Inuwa B. , Yiltawe W. , Shittu I. , Meseko C. , Kia G. 
Published: November 2023

Since the first 2006 Avian Influenza (AI) outbreak in Nigeria, it has continued to circulate and ravage the poultry industry with huge economic losses above 130 billion naira. Local poultry are important sources of AI transmission and maintenance of the highly pathogenic avian influenza H5N1. Live bird markets (LBMs) are “breeding grounds” and major risk factors for human infection of AI. The seroprevalence of AI in local chickens in LBMs in Kaduna Metropolis, Nigeria was determined. Sera were obtained from the local chickens (n=300) in 5 daily LBMs and subjected to competitive enzyme-linked immunosorbent assay (c-ELISA) to detect the nucleoprotein antibodies. The c-ELISA positive samples were further screened by haemagglutination inhibition (HI) test for AI using H5, H7 and H9 antigens. The overall AI seroprevalence was 1.7 % with the highest individual seroprevalence of 3.3% in Kawo and Railway LBMs. There was no statistically significant association between the location of LBMs and AI presence, and between the sex and presence of AI antibodies (p = 0.427). One sample was HI positive for antibodies against H5, H7 and H9 with mean titers of 4, 2.5 and 3.5 log2, respectively. This implies the potential danger of the spread of AI among humans and animals. There should be sustained surveillance and biosecurity in the live bird market.
Characterization and antifungal susceptibility of <i>Trichophyton mentagrophytes</i> isolated from a goat presented with severe dermatophytosis in Zaria, Nigeria
Authors: Dalis J.S. , Kazeem H.M. , Chah K.F. 
Published: November 2023

Dermatophytosis is a contagious skin disease affecting domestic and wild animals with considerable zoonotic significance. The disease is caused by fungi known as dermatophytes in the genera Trichophyton, Microsporum and Epidermophyton. A goat was observed with circumscribed alopecic, highly inflammatory, thickly crusted skin lesions on the head region, especially around the eyes. Skin scraping, including hair pullouts, was aseptically obtained and processed for direct examination, isolation and microscopic identification of etiologic agent and supplemented with urease test. The isolate was tested for its susceptibility to fluconazole, griseofulvin, itraconazol and ketoconazole. Direct examination revealed hyaline, septate hyphae in skin scales and chains of endothrix spores within hair shafts, suggesting Trichophyton infection. Colonies on Sabouraud’s dextrose agar were white, flat and granular. Microscopic examination of the isolate revealed many oval micro-conidia arranged in grapelike clusters with multi-septate, club- shaped, thin, and smooth-walled macroconidia typical of Trichophyton mentagrophytes. The isolate was urease-positive and sensitive to itraconazole and ketoconazole but resistant to fluconazole and griseofulvin. It was concluded that T. mentagrophytes was the cause of the severe skin lesions in the goat. The need to perform antifungal susceptibility testing on dermatophytes isolated from clinical specimens for effective management of dermatophytosis was emphasized.
Pengalaman Bersama Ganja: Transformasi Menjadi Pengguna Ganja
Authors: Satya Parama I Dewa Made 
Published: November 2023

Penelitian ini berfokus pada dinamika kehidupan pengguna ganja di Bali dengan menggunakan konsep Howard S. Becker tentang karier penyimpangan untuk memahami proses transformasi seseorang menjadi pengguna ganja. Karier penyimpangan dalam konteks pengguna ganja ialah suatu proses sosial yang dirangkai dalam hubungan konseptual dan pengalaman dengan ganja yang berkembangan melalui interaksi dengan orang lain.. Adapun penelitian ini bertujuan untuk memahami proses dinamika pembentukan karier pengguna ganja. Penelitian ini menggunakan metode kualitatif dengan pendekatan life history yang berguna untuk merekam cerita berdasarkan pengalaman pengguna ganja. Teknik pengumpulan data meliputi wawancara, observasi, dokumentasi dan catatan lapangan. Objek penelitian ini adalah tiga orang pengguna ganja aktif yang memiliki latar belakang penggunaan ganja dalam waktu lama. Teknik pengumpulan data yang digunakan adalah in-depth interview semi terstruktur. Berdasarkan hasil penelitian, terdapat tiga tahapan dalam proses pembentukan karier pengguna ganja mencakup permulaan karier, pengembangan karier dan karier reguler. Ketiga tahapan ini memiliki nuansa dinamika yang berbeda dan juga dapat diartikan sebagai proses sosial yang dijalani individu dalam membentuk suatu karier pengguna ganja.
Prognosis of Zero Coronary Artery Calcium Score in Symptomatic Patients of South Asian Descent – An Experience From a Tertiary Care Center in Pakistan
Authors: Shams Pirbhat , Sultan Fateh Ali Tipoo , Sultan Aiman , Javed Umair 
Published: November 2023

Objectives: To estimate the prevalence of non-calcified coronary artery disease in patients with chest pain and a zero coronary artery calcium score, and to assess the prognostic significance of a zero coronary artery calcium score in these symptomatic patients.
Methodology: All consecutive patients who underwent a CT coronary angiogram (CTCA) for evaluation of angina or angina-equivalent symptoms from 2009 to December 2020 were enrolled retrospectively. Patients with prior myocardial infarction, history of revascularization, and congenital heart disease were excluded. Follow-up data was collected by using the hospital's electronic patient record system and telephone communication. The endpoint, major-adverse cardiovascular events (MACE) was defined as the total of cardiac death, non-fatal myocardial infarction, and/or non-elective revascularization.
Results: A total of 534 patients were enrolled after final exclusion. The mean age was 53 years ± 11. Males constituted 68.4% of the study population. Dyslipidemia was the most common co-morbid condition identified (50%), followed by diabetes (18.4%) and hypertension (3.6%). Chest pain was the most common presenting complaint (97.4%) followed by dyspnea. At least 28.8% of patients with zero CAC scores had the presence of coronary artery disease (soft plaque) of any degree. Obstructive CAD (>50%) was present in 5.8% of patients. Follow-up was available for 61.4% of patients. The mean follow-up duration was 96.6 months ± 49.8 (range 21 – 194 months). All-cause Major Adverse Cardiovascular Event (MACE) was observed in 8.8% of patients. The most common MACE outcome was angina (3.96%) and all-cause mortality (3%). Only 2.7% required revascularization on follow-up with 1.2% having myocardial infarction and non-urgent revascularization. The baseline characteristics, all-cause MACE (p = 0.79), mortality (0.82), angina (p = 0.765), revascularization (p = 0.45), non-fatal MI, and non-elective revascularization (p = 0.6) did not differ significantly in patients with and without obstructive CAD. The baseline characteristics did not differ significantly between patients with and without MACE.
Conclusion: The incidence of soft plaque in this South Asian cohort is higher than that reported in international studies. However, in symptomatic South Asians, a CAC score of zero carries a good long-term prognosis, irrespective of the degree of CAD.
Cytochrome P450 2C19*2 Genetic Polymorphism in Patients with Acute Coronary Syndrome
Authors: Ullah Nazeef 
Published: November 2023

Objectives: The study aimed to investigate the association between CP2C19*2 loss of function polymorphism and acute coronary syndrome (ACS) patients receiving Clopidogrel. It compared genotype frequencies of heterozygous GA, homozygous GG, and homozygous AA between ACS patients and healthy controls. The study assessed the statistical significance of the association in the Pakistani cohort. It contributed to understanding the role of genetic polymorphisms in response to Clopidogrel therapy in ACS patients and provided insights into the need for pharmacogenomics testing for patients with CAD, particularly in the Asian population, who are poor metabolizers and require long-term Clopidogrel therapy.
Methodology: COHORT Study.
Results: The study found no statistically significant association between the CYP2C19*2 loss of function polymorphism and acute coronary syndrome (ACS) in the Pakistani cohort. The frequency of the CP2C19*2 heterozygous GA genotype was 38.3% in ACS patients and 29.5% in control subjects, while the homozygous GG genotype was 58.7% in patients and 59.0% in controls. The homozygous AA genotype was 3.4% in patients and 11.4% in controls.
The genotype frequency analysis showed that the wild type GG genotype was lower in patients (58.7%) compared to controls (59.0%), while the mutant AA genotype was also lower in patients (3.4%) compared to controls (11.4%). The heterozygous GA genotype was higher in patients (38.3%) compared to controls (29.5%).
The population studied was in Hardy Weinberg equilibrium, with a frequency of mutant allele A at 0.26 and wild type allele G at 0.73.
Conclusion: The study concludes that the CYP2C19*2 loss of function polymorphism is not associated with acute coronary syndrome (ACS) in the Pakistani cohort. The distribution of the CP2C19*2 genetic polymorphism was not statistically significant between ACS patients and healthy controls.
The genotype frequency analysis showed no significant differences in the distribution of the heterozygous GA, homozygous GG, and homozygous AA genotypes between the patient and control groups.
The population studied was in Hardy Weinberg equilibrium, with a frequency of mutant allele A at 0.26 and wild type allele G at 0.73.
Recomendaciones para la inmunización con vacuna recombinante para herpes zóster en pacientes con enfermedades reumáticas inflamatorias crónicas autoinmunes
Authors: Bonvehí Pablo , Citera Gustavo , Cosentino Vanesa , De la Vega María Celina , Larroudé María Silvia , Nacinovich Francisco , Schneeberger Emilce , Vázquez Hebe , Zamora Natalia , Sorrentino Laura , Felquer María Laura , Vergara Facundo 
Published: November 2023

En enero-febrero de 2022 se publicó el último consenso de recomendaciones de vacunas en adultos con enfermedades reumáticas inflamatorias crónicasautoinmunes (ERICA), realizado en conjunto con expertos de la Sociedad Argentina de Reumatología y la Sociedad Argentina de Infectología (SAR/SADI) Amodo de addendum del mismo, desarrollamos las recomendaciones para la inmunización con la vacuna recombinante para herpes zóster (VRHZ) en la población de pacientes con ERICA.
En el último año, en Argentina, se aprobó la vacuna para el virus varicela zóster, vacuna inactivada de subunidades, recombinante, que contiene la glicoproteína E del virus de la varicela zóster junto con el sistema adyuvante AS0I.
La misma demostró una alta eficacia y seguridad en la población inmunocompetente, así como en poblaciones de pacientes con inmunocompromiso. Por este motivo, en conjunto con un grupo de infectólogos expertos, desarrollamos las recomendaciones para el uso de esta vacuna en la población de pacientes con ERICA.
Este documento se divide en dos partes. En la primera, figuran las recomendaciones de vacunación en distintos escenarios de presentación habitual en la práctica diaria. Se realizó una revisión bibliográfica y un consenso de expertos para los puntos que contaban con menor evidencia. La segunda parte consiste en seis recomendaciones desarrolladas a través de la metodología GRADE. Seanalizó la evidencia en la población de pacientes con ERICA, con o sin tratamiento inmunosupresor, observándose una respuesta de la vacuna VRHZ aceptable, tanto humoral como celular, y demostrando ser segura en esta población de pacientes. Por otro lado, se comprobó una alta eficacia/efectividad en prevenir episodios de herpes zóster y neuralgia posherpética, así como una mayor eficacia/efectividad que la vacuna a virus vivo atenuado.
En conclusión, en base a la evidencia disponible, este panel de expertos recomienda la vacuna VRHZ en pacientes con ERICA, independientemente de que hayan recibido previamente la vacuna a virus vivo atenuado contra el herpes zóster, ya que es segura, efectiva y, por el momento,tampoco se asoció a reactivación/brote de la enfermedad de base.
ANALISIS KESEHATAN PERMODALAN, KUALITAS AKTIVA PRODUKTIF, DAN LIKUIDITAS KOPERASI SIMPAN PINJAM PEMBIAYAAN SYARIAH PERMATA WONOGIRI PERIODE 2018- 2020
Authors: Husin Ahmad 
Published: November 2023

Penelitian ini bertujuan untuk mengetahui tingkat kesehatan keuangan dari Koperasi Simpan Pinjam dan Pembiayaan Syariah Permata Wonogiri melalui analisis permodalan, kualitas aktiva produktif, dan likuiditas. Metode yang digunakan pada penelitian ini adalah metode kuantitatif. Populasi dalam penelitian ini adalah laporan keuangan Koperasi Simpan Pinjam dan Pembiayaan Syariah Permata Wonogiri mulai tahun berdirinya sampai dengan tahun 2020. Penelitian ini diambil dari laporan keuangan selama 3 (tiga) tahun terakhir (tahun 2018, 2019, dan 2020). Teknik pengumpulan data melalui studi dokumentasi. Kemudian langsung dianalisis dengan teknik analisis kuantitatif. Dari hasil analisis data tes terbukti bahwa: (1) Rasio Kecukupan Modal (CAR) pada tahun 2018, 2019, dan 2020 memperoleh skor 5.00 pada skala 5.00, sehingga berada dalam kategori SEHAT (H1 terbukti); (2) Rasio Penyisihan Penghapusan Aktiva Produktif (PPAP) pada tahun 2018, 2019, dan 2020 berada pada skor 5,00 dalam skala 5.00 dan berada pada kategori LANCAR (H2 terbukti); (3) Rasio Pembiayaan terhadap Dana yang diterima pada tahun 2018, 2019, dan 2020 berada pada skor 5,00 dalam skala 5.00, sehingga berada pada kriteria LIKUID (H3 tidak terbukti).