bluuebunny/crossref_metadata_2025_split huggingface dataset:
Marketing Modernity, Selling Hazeline: A Comparative Study of Indian and Chinese Markets, 1908–1957
Authors: Geng Yushu , Hussain Mobeen 
Published: December 2023

AbstractThis article explores how the experiences of colonial modernity were constituted through global advertising by examining the transnational marketing of Hazeline Snow in early twentieth-century India and China. Manufactured by London-based pharmaceutical company Burroughs Wellcome Company (BWC), Hazeline Snow was a globally circulated medical-cosmetic commodity that showcased the advance of colonial modernity in Asia in the early twentieth century. Focusing on the convergences and divergences in the textual and visual representations of gender, beauty, and race in Chinese and Indian Hazeline Snow advertisements, this article illustrates the uneven ways in which capitalism created, disseminated, and adapted to different knowledge systems in distinct colonial contexts. It argues that modern beauty ideals promoted by cosmetics advertising were not simply the diffusion of a hegemonic Western modernity driven by the symbiotic expansion of capitalism and colonialism, but were shaped by the entanglement of global transformations and local conditions, including pre-colonial aesthetic value systems, inter-Asia exchanges, and competition from both local and other colonial actors. As ‘Snows’ became a specific kind of Asian commodity in their own right, the meanings of being modern and being beautiful was no longer the preserve of a specific company or a generalized ‘West’.
Balancing between competition and regulation in healthcare markets
Authors: Trottmann Maria , Stam Piet , Visser Johan , Brammli-Greenberg Shuli 
Published: December 2023

Abstract
Systems of managed competition naturally seek the middle ground between competition and regulation. This debate essay makes the case for adjusting the level of regulation according to the characteristics of the submarket in question. We first develop a theoretical framework that can be used to identify the services in which relatively free competition will be beneficial. The framework is grounded in the economic literature and consists of eight criteria. Targeted regulatory tools are then discussed that can be used to structure submarkets in which these criteria are not (fully) met. Applying this framework and targeted interventions, regulators gain the flexibility to react to potential market failures, without foregoing the benefits of managed competition where it works well. This analysis is highly relevant for countries in transition to managed competition. Regulators can identify potential failure in submarkets for medical services, and apply the necessary regulatory tools to prepare for a smooth transition.
Construct Validity and Measurement Invariance of the eHEALS in a	Diverse US High School Sample
Authors: Joseph Patrece L. , Fleary Sasha A. 
Published: December 2023

Abstract: Although the eHealth Literacy Scale (eHEALS) is a widely used measure of eHealth literacy (eHL), it has not been validated in a diverse sample of US adolescents. This study assessed the construct validity and item and measurement invariance of the eHEALS using both Rasch analyses and classical test theory (CTT). Data were collected from adolescents at a US Northeastern high school ( N = 355, 64.9% were 16–18-years old, 54.8% male, 76.4% from a racially minoritized group, and 50.5% Latinx). Adolescents completed a survey that included demographic variables (i.e., age in years, gender, and ethnicity) and the eHEALS. Using Rasch and CTT methodologies, the dimensionality of the eHEALS and item and measurement invariance across gender, age, and ethnicity were assessed. The unidimensional structure of the eHEALS as well as item and measurement invariance across gender, age, and ethnicity were supported. Rasch analyses also suggested that responses to eHEALS items can be summed to determine eHL abilities, although there was a ceiling effect. The eHEALS is a unidimensional measure of eHL that may provide information in health education settings about adolescents’ eHL skills. It performs similarly across male and female as well as older and younger adolescents. However, given the ceiling effect and changes in adolescents’ Internet use since its development, future studies should revise the eHEALS to better capture adolescents’ eHL abilities. Future studies should also examine item and measurement invariance by age (in years), race, family income, and longitudinally to determine the usefulness of the measure across groups and time.
Largest Aftershock Nucleation Driven by Afterslip During the 2014 Iquique Sequence
Authors: Itoh Yuji , Socquet Anne , Radiguet Mathilde 
Published: December 2023

AbstractVarious earthquake models predict that aseismic slip modulates the seismic rupture process but actual observations of such seismic‐aseismic interaction are scarce. We analyze seismic and aseismic processes during the 2014 Iquique earthquake sequence. High‐rate Global Positioning System displacements demonstrate that most of the early afterslip is located downdip of the M 8.1 mainshock and is accompanied by decaying aftershock activity. An intriguing secondary afterslip peak is located ∼120 km south of the mainshock epicenter. The area of this secondary afterslip peak likely acted as a barrier to the propagating mainshock rupture and delayed the M 7.6 largest aftershock, which occurred 27 hr later. Interevent seismicity in this secondary afterslip area ended with a M 6.1 near the largest aftershock epicenter, kicking the largest aftershock rupture in the same area. Hence, the interevent afterslip likely promoted the largest aftershock nucleation by destabilizing its source area, favoring a rate‐dependent cascade‐up model.
Rafting of Growing Antarctic Sea Ice Enhances In‐Ice Biogeochemical Activity in Winter
Authors: Audh Riesna R. , Fawcett Sarah E. , Johnson Siobhan , Rampai Tokoloho , Vichi Marcello 
Published: December 2023

AbstractThe study of Antarctic first‐year sea‐ice biogeochemistry has been limited by samples mostly being collected in pack ice during summer, with few winter data available. Measurements from the Antarctic marginal ice zone (AMIZ) have proven even more difficult to obtain. The AMIZ is a broad, circumpolar feature of the Southern Ocean found at different latitudes during the year where light and nutrients are high enough to sustain primary production and influence ecosystem functioning. We present the first biogeochemical data set from growing ice collected in the Atlantic AMIZ during winter 2019, including measurements from young pancake ice (YI) and consolidated first‐year ice (FYI). Measurements of sea‐ice temperature, salinity, crystal structure, δ18O, chlorophyll, and nutrient concentrations were used to investigate the winter sea‐ice habitat and decipher the conditions under which the ice formed and grew. Model simulations support the hypothesis that nutrient accumulation in advancing sea ice cannot be explained by passive seawater entrainment and thermodynamics alone. Our data confirm that winter sea ice is biogeochemically active and accumulates remineralized nutrients. We further propose that mechanical thickening enhances the reservoir of nutrients during the ice growth season. The biogeochemical transition from YI to FYI does not appear to be a linear progression of thickness with habitat space reduction as sea ice consolidates. Instead, FYI bulk biogeochemistry results from multiple cycles of rafting of YI, which conserves the biogeochemical properties of YI in the FYI, ultimately increasing the overall nutrient and chlorophyll content.
A novel autism-associated UBLCP1 mutation impacts proteasome regulation/activity
Authors: Soueid Jihane , Hamze Zeinab , Bedran Joe , Chahrour Maria , Boustany Rose-Mary 
Published: December 2023

AbstractThe landscape of autism spectrum disorder (ASD) in Lebanon is unique because of high rates of consanguinity, shared ancestry, and increased remote consanguinity. ASD prevalence in Lebanon is 1 in 68 with a male-to-female ratio of 2:1. This study aims to investigate the impact of an inherited deletion in UBLCP1 (Ubiquitin-Like Domain-Containing CTD Phosphatase 1) on the ubiquitin-proteasome system (UPS) and proteolysis. Whole exome sequencing in a Lebanese family with ASD without pathogenic copy number variations (CNVs) uncovered a deletion in UBLCP1. Functional evaluation of the identified variant is described in fibroblasts from the affected. The deletion in UBLCP1 exon 10 (g.158,710,261CAAAG > C) generates a premature stop codon interrupting the phosphatase domain and is predicted as pathogenic. It is absent from databases of normal variation worldwide and in Lebanon. Wild-type UBLCP1 is widely expressed in mouse brains. The mutation results in decreased UBLCP1 protein expression in patient-derived fibroblasts from the autistic patient compared to controls. The truncated UBLCP1 protein results in increased proteasome activity decreased ubiquitinated protein levels, and downregulation in expression of other proteasome subunits in samples from the affected compared to controls. Inhibition of the proteasome by using MG132 in proband cells reverses alterations in gene expression due to the restoration of protein levels of the common transcription factor, NRF1. Finally, treatment with gentamicin, which promotes premature termination codon read-through, restores UBLCP1 expression and function. Discovery of an ASD-linked mutation in UBLCP1 leading to overactivation of cell proteolysis is reported. This, in turn, leads to dysregulation of proteasome subunit transcript levels as a compensatory response.
ANKS1B encoded AIDA-1 regulates social behaviors by controlling oligodendrocyte function
Authors: Cho Chang Hoon , Deyneko Ilana Vasilisa , Cordova-Martinez Dylann , Vazquez Juan , Maguire Anne S. , Diaz Jenny R. , Carbonell Abigail U. , Tindi Jaafar O. , Cui Min-Hui , Fleysher Roman , Molholm Sophie , Lipton Michael L. , Branch Craig A. , Hodgson Louis , Jordan Bryen A. 
Published: December 2023

AbstractHeterozygous deletions in the ANKS1B gene cause ANKS1B neurodevelopmental syndrome (ANDS), a rare genetic disease characterized by autism spectrum disorder (ASD), attention deficit/hyperactivity disorder, and speech and motor deficits. The ANKS1B gene encodes for AIDA-1, a protein that is enriched at neuronal synapses and regulates synaptic plasticity. Here we report an unexpected role for oligodendroglial deficits in ANDS pathophysiology. We show that Anks1b-deficient mouse models display deficits in oligodendrocyte maturation, myelination, and Rac1 function, and recapitulate white matter abnormalities observed in ANDS patients. Selective loss of Anks1b from the oligodendrocyte lineage, but not from neuronal populations, leads to deficits in social preference and sensory reactivity previously observed in a brain-wide Anks1b haploinsufficiency model. Furthermore, we find that clemastine, an antihistamine shown to increase oligodendrocyte precursor cell maturation and central nervous system myelination, rescues deficits in social preference in 7-month-old Anks1b-deficient mice. Our work shows that deficits in social behaviors present in ANDS may originate from abnormal Rac1 activity within oligodendrocytes.
Large exchange bias enhancement and control of ferromagnetic energy landscape by solid-state hydrogen gating
Authors: Hasan M. Usama , Kossak Alexander E. , Beach Geoffrey S. D. 
Published: December 2023

AbstractVoltage control of exchange bias is desirable for spintronic device applications, however dynamic modulation of the unidirectional coupling energy in ferromagnet/antiferromagnet bilayers has not yet been achieved. Here we show that by solid-state hydrogen gating, perpendicular exchange bias can be enhanced by > 100% in a reversible and analog manner, in a simple Co/Co0.8Ni0.2O heterostructure at room temperature. We show that this phenomenon is an isothermal analog to conventional field-cooling and that sizable changes in average coupling energy can result from small changes in AFM grain rotatability. Using this method, we show that a bi-directionally stable ferromagnet can be made unidirectionally stable, with gate voltage alone. This work provides a means to dynamically reprogram exchange bias, with broad applicability in spintronics and neuromorphic computing, while simultaneously illuminating fundamental aspects of exchange bias in polycrystalline films.
Finite-temperature screw dislocation core structures and dynamics in α-titanium
Authors: Liu Anwen , Wen Tongqi , Han Jian , Srolovitz David J. 
Published: December 2023

AbstractA multiscale approach based on molecular dynamics (MD) and kinetic Monte Carlo (kMC) methods is developed to simulate the dynamics of an 〈a〉 screw dislocation in α-Ti. The free energy barriers for the core dissociation transitions and Peierls barriers for dislocation glide as a function of temperature are extracted from the MD simulations (based on machine learning interatomic potentials and optimization); these form the input to kMC simulations. Dislocation random walk trajectories from kMC agree well with those predicted by MD. On some planes, dislocations move via a locking-unlocking mechanism. Surprisingly, some dislocations glide in directions that are not parallel with the core dissociation direction. The MD/kMC multiscale method proposed is applicable to dislocation motion in simple and complex materials (not only screw dislocations in Ti) as a function of temperature and stress state.
Mechanism elucidation and scaling control in membrane distillation using 3D printed carbon nanotube spacer
Authors: Jeong Seongeom , Gu Boram , Park Sanghun , Cho Kyunghwa , An Alicia Kyoungjin , Jeong Sanghyun 
Published: December 2023

AbstractMembrane scaling is a barrier to membrane distillation (MD). In this study, 3D-printed carbon nanotube (CNT) spacer was used to investigate its capability for mitigating membrane scaling during MD and to elucidate the scaling mechanism experimentally and theoretically. CNT spacer was tested under temperature-dependent calcium sulfate scaling conditions, and optical coherence tomography (OCT) and scanning electron microscopy (SEM) were used to measure scaling quantitatively. CNT spacer exhibited unique membrane scaling mechanism, where only a 37% reduction (29 Lm−2h−1) in the initial flux was achieved, even above a volume concentration factor (VCF) of 4. On the other hand, the membrane with a polylactic acid (PLA) spacer (controls) entirely lost flux before reaching a VCF of 3.5. Interestingly, bubble formation was observed in CNT spacer, which could be attributed to the enhanced flux and vaporization rate on membrane surface in the presence of rough-surfaced CNT spacer. Bubbly flow along the membrane channel with CNT spacer can potentially reduce surface scaling on membrane during MD. Moreover, due to the surface roughness of CNT spacer, the initial nuclei might be detached more easily from CNT spacer surface than from smooth PLA surface and grow further into larger crystals in the bulk, resulting in reduced dissolved solutes in the solution. This phenomenon was indirectly corroborated by comparing the experimentally measured fluxes and theoretically computed values from our mechanistic model of MD-crystallization developed in this study. Therefore, this study revealed that CNT spacer with rough surfaces can potentially have benefit of mitigating membrane scaling during MD.
Active polypeptide MDANP protect against necrotizing enterocolitis (NEC) by regulating the PERK-eIF2ɑ-QRICH1 axis
Authors: Huo Jie , Zhang Rui , Wu Xinping , Fu Changchang , Hu Jinhui , Hu Xiaohan , Sun Wenqiang , Chen Zhenjiang , Zhu Xueping 
Published: December 2023

AbstractThe effect of MDANP effects on ER stress signalling not well known or elucidated. Endoplasmic reticulum (ER) stress plays a critical role in necrotizing enterocolitis (NEC) pathogenesis through the PERK-eIF2ɑ-QRICH1 axis. The present study aimed to explore the protective effects of MDANP in NEC development. Firstly, a function screening was designed to identify the candidate peptides in human milk, and then the identified peptides were validated in NEC patients. In vivo, NEC was induced in mice pups and divided into four groups: (1) control group, (2) NEC group, (3) MDANP + NEC group, and (4) NS + NEC group. In vitro, lentivirus-mediated QRICH1 silencing, was used to transfect NCM460 cell lines, then stimulated with LPS. After LPS stimulation, cells were treated with chemically synthesized MDANP, and the essential proteins in the QRICH1 signalling pathway in cells were tested and compared. After the small-scale screening, a peptide (SKSKKFRRPDIQYPDATDED) named MDANP was determined as the principal peptide. Its protective effect against NEC through inhibiting the expression of ERS key proteins and impeding the intestinal cells’ apoptosis was observed in the animal models. Furthermore, the inhibitive effect of MDANP on apoptosis of intestinal epithelial cells through modulating the PERK-eIF2ɑ-QRICH1 ERS pathway was also confirmed in vitro. Taken together, our data suggest that MDANP effectively ameliorates apoptosis in NEC through attenuating PERK-eIF2ɑ-QRICH1.
Peripheral clock gene oscillations are perturbed in neonatal and adult rat offspring raised under adverse limited bedding conditions
Authors: Walker Claire-Dominique , Delorme Tara C. , Kiessling Silke , Long Hong , Cermakian Nicolas 
Published: December 2023

AbstractCircadian (24-h) rhythms in the suprachiasmatic nucleus (SCN) are established in utero in rodents, but rhythmicity of peripheral circadian clocks appears later in postnatal development. Since peripheral oscillators can be influenced by maternal feeding and behavior, we investigated whether exposure to the adverse environmental conditions of limited bedding (LB) during postnatal life would alter rhythmicity in the SCN, adrenal gland and liver in neonatal (postnatal day PND10), juvenile (PND28) and adult rats. We also examined locomotor activity in adults. Limited bedding increased nursing time and slightly increased fragmentation of maternal behavior. Exposure to LB reduced the amplitude of Per2 in the SCN on PND10. Adrenal clock gene expression (Bmal1, Per2, Cry1, Rev-erbα, Dbp) and corticosterone secretion were rhythmic at all ages in NB offspring, whereas rhythmicity of Bmal1, Cry1 and corticosterone was abolished in neonatal LB pups. Circadian gene expression in the adrenal and liver was well established by PND28. In adults, liver expression of several circadian genes was increased at specific daytimes by LB and the microstructure of locomotor behavior was altered. Thus, changes in maternal care and behavior might provide important signals to the maturing peripheral oscillators and modify, in particular their output functions in the long-term.
A new toothless pterosaur from the Early Cretaceous Jehol Biota with comments on the Chaoyangopteridae
Authors: Wang Xiaolin , Kellner Alexander W. A. , Jiang Shunxing , Chen He , Costa Fabiana R. , Cheng Xin , Zhang Xinjun , Nova Bruno C. Vila , de Almeida Campos Diogenes , Sayão Juliana M. , Rodrigues Taissa , Bantim Renan A. M. , Saraiva Antônio A. F. , Zhou Zhonghe 
Published: December 2023

AbstractThe Chaoyangopteridae is a clade of azhdarchoid pterosaurs that stands out in China, particularly in the Jehol Biota, as a Cretaceous group of medium-sized and high-crested pterosaurs. Herein, we describe a new species, Meilifeilong youhao gen. et sp. nov., based on two specimens, one tentatively referred to this taxon. This new species represents the most complete and well-preserved chaoyangopterid recorded to date. Along with a set of characters (low premaxillary crest above the nasoantorbital fenestra extending posteriorly, posterior premaxillary process arched and curving posteriorly, a slightly convex sternal articulation surface of coracoid, and a fibular shaft close to proximal articulation strongly arched posteriorly), this species also provides new information both on the unknown palatal region of this clade, and on the rarely preserved (in place) ear portion with stapes. Moreover, M. youhao sheds light on paleoecological aspects, while also giving new information about the taxonomic diversity of this peculiar group of Jiufotang pterosaurs.
Open plains are not a level playing field for hominid consonant-like versus vowel-like calls
Authors: Gannon Charlotte , Hill Russell A. , Lameira Adriano R. 
Published: December 2023

AbstractAfrica’s paleo-climate change represents an “ecological black-box” along the evolutionary timeline of spoken language; a vocal hominid went in and, millions of years later, out came a verbal human. It is unknown whether or how a shift from forested, dense habitats towards drier, open ones affected hominid vocal communication, potentially setting stage for speech evolution. To recreate how arboreal proto-vowels and proto-consonants would have interacted with a new ecology at ground level, we assessed how a series of orangutan voiceless consonant-like and voiced vowel-like calls travelled across the savannah. Vowel-like calls performed poorly in comparison to their counterparts. Only consonant-like calls afforded effective perceptibility beyond 100 m distance without requiring repetition, as is characteristic of loud calling behaviour in nonhuman primates, typically composed by vowel-like calls. Results show that proto-consonants in human ancestors may have enhanced reliability of distance vocal communication across a canopy-to-ground ecotone. The ecological settings and soundscapes experienced by human ancestors may have had a more profound impact on the emergence and shape of spoken language than previously recognized.
Exploring the electronic structure, mechanical behaviour, thermal and high-temperature thermoelectric response of CoZrSi and CoZrGe Heusler alloys
Authors: Gurunani Bharti , Gupta Dinesh C. 
Published: December 2023

AbstractBy using density functional theory, we have explored the structural, electro-mechanical, thermophysical and thermoelectric properties of CoZrSi and CoZrGe Heusler alloys. The ground state stability was determined by optimising the energy in various configurations like type I, II, and III. It was found that these alloys stabilized in the ferromagnetic phase in type I. We employed the Generalised Gradient Approximation and modified Becke-Johnson potentials to explore the electronic structure. The band structures of each of these Heusler alloys exhibit a half-metallic nature. Additionally, the computed second-order elastic parameters reveal their ductile nature of them. To understand the stability of the alloys at different pressures and temperatures, we investigated various thermodynamic parameters using the Quasi-Harmonic Debye model. We obtained the transport coefficients using the Boltzmann theory. Our findings indicate that these alloys can be used in spintronics and thermoelectric domains.