bluuebunny/crossref_metadata_2025_split huggingface dataset:
Foreign Policy Issues of the Republic of Turkey and the United States in the Period after the End of the Cold War until the 2020
Authors: Makaradze Emzar , Makaradze Beka 
Published: November 2023

At the beginning of the 21st century, in 2002, a new political era began with the arrival of Recep Tayyip Erdogan and the Islam-oriented Justice and Development Party (AKP) at the head of the Republic of Turkey, which was gradually followed by changes in both foreign and domestic policy of the country.
The main ideologist of modern Turkey’s foreign policy is one of the founders of the Justice and Development Party and Erdogan’s ally, former Foreign Minister and Prime Minister Professor Ahmet Davutoglu, who outlined the strategic priorities of Turkey’s foreign policy in his pioneering work Strategic Depth. In his doctrine, Ahmet Davutoglu argues that Turkey has “strategic depth” that allows it to pursue an independent foreign policy and claims to be the leading state in the region.
As we know, the Republic of Turkey is located at the crossroads of Europe and Asia. According to the doctrine, precisely because of its geographical position and historical ties, it has a desire to influence all these regions (the Middle East, the Balkans, the Caucasus, Central Asia, the Mediterranean, the Persian Gulf, and the Black Sea), what is considered the core of neo-Ottoman ideology.
Neo-Ottomanism implies a shift of the Turkish political vector from West to East. Since the beginning of the 21st century, neo-Ottomanism as an ideology has become a force responsible for the shape of political life of Turkey. According to the ideology of neo-Ottomanism, the Republic of Turkey must get rid of the subordination of the United States, which will allow it to put itself on a par with such states as Britain, France, Russia, and China.
Neo-Ottomanism is the main ideological direction of the new foreign policy of the Republic of Turkey. One of the arguments used by Erdogan and his party in moving from a parliamentary to a presidential model is the fact that the country needs a government that is almost as strong and centralized as the Ottoman Empire. At the same time, the president himself and his entourage constantly emphasize that the Turks are the “heirs of the Ottomans” and that the country must return to its former glory and strengthen its political, economic and cultural influence in the former territories of the Ottoman Empire.
Thus, neo-Ottomanism is part of the official ideology of the Justice and Development Party and the basis of the country’s new identity, shaped by the political elite over the years. Although there is no direct indication of Turkish regional hegemony in the “strategic depth”, most analysts, especially in the West, believe that the expansion of spheres of influence mentioned in the doctrine is, in fact, nothing more than the restoration of Turkey’s monopoly hegemony in the region, but this times by means adapted to the modern era, in particular through the use of political, economic and cultural expansion and other “soft power” tools.
Familial renal glucosuria presenting as paroxysmal glucosuria and hypercalciuria due to a novel SLC5A2 heterozygous variant
Authors: Van Lerberghe Robin , Mahieu Elien , Vanuytsel Johan , Vanhaute Karen , Vanfraechem Celine , Claeys Laurens 
Published: November 2023

Familial renal glucosuria (FRG) is a rare genetic disease characterised by isolated glucosuria in the absence of proximal tubular dysfunction. It usually occurs due to a mutation in the SLC5A2 gene encoding the sodium-glucose cotransporter-2 (SGLT2), responsible for most of the renal glucose reabsorption. We report on a case of a patient presenting with paroxysmal glucosuria and hypercalciuria due to a novel SLC5A2 heterozygous variant.
Cancer cell detection by plasmonic dual V-shaped PCF biosensor
Authors: Abdelghaffar M. , Gamal Yusuf , El-Khoribi Reda A. , Soliman Wafaa , Badr Y. , Hameed Mohamed Farhat O. , Obayya S. S. A. 
Published: November 2023

In this paper, a highly sensitive plasmonic photonic crystal fiber (PCF) biosensor is reported for cancer cell detection. The modal analysis of the reported biosensor is performed using the full vectorial finite element method. The suggested PCF sensor has dual V-shaped groves to enhance the sensor sensitivity where two gold nano-rods are mounted on the etched surfaces. The main idea of the optical sensors is to track the electromagnetic coupling between the leaky core mode and the surface plasmon mode (SPM) at the metal/dielectric interface. When the SPM and one of the fundamental core modes are phase-matched, strong coupling occurs. Therefore, maximum confinement loss is achieved for the core-guided mode at the resonance wavelength, which depends on the analyte refractive index (RI). The V-shaped groove enhances the core/SPM coupling where high RI sensitivity of 24,000 nm/RIU is achieved along the RI range from 1.38 to 1.39, with a resolution of 2.703×10−6RIU. The potential of using the suggested RI sensor for cancer cell detection is then demonstrated. In this context, high sensitivities of 23,700 nm/RIU, 8,208 nm/RIU, and 14,428.6 are obtained for basal, cervical, and breast cancer cells with resolutions of 4.22×10−6RIU, 12.18×10−6RIU, and 6.93×10−6RIU, respectively. The achieved sensitivity and resolution are higher than those of the recently reported cancer biosensors. Moreover, the developed label-free biosensor is safer than other chemical and surgical techniques.
Influence of the interaction geometry on the fidelity of the two-qubit Rydberg blockade gate
Authors: Vybornyi I. , Gerasimov L. V. , Kupriyanov D. V. , Straupe S. S. , Tikhonov K. S. 
Published: November 2023

We present a comparative analysis of physical constraints limiting the quality of spin entanglement created using the Rydberg blockade technique in an ensemble of trapped neutral 87Rb atoms. Based on the approach developed earlier in Phys. Rev. A 106, 042410 (2022)PLRAAN1050-294710.1103/PhysRevA.106.042410, we consider the complete multilevel Zeeman structure of the interacting atoms and apply our simulations to two excitation geometries featured by different transition types, both feasible for experimental verification. We demonstrate that the blockade shift strongly depends not only on the interatomic separation but also on the angular position of the atom pair with respect to the quantization axis determined by polarization of the driving fields. As an example, we have estimated fidelity for a promising design of a CZ gate, recently proposed by Levine et al. [Phys. Rev. Lett. 123, 230501 (2019)PRLTAO0031-900710.1103/PhysRevLett.123.230501] for various possible experimental geometries. Anisotropic effects in entangling gates considered here are important for the optimal choice of proper geometry for quantum computing in two- and three-dimensional arrays of atomic qubits and are of considerable interest for quantum simulators, especially those that are designed for anisotropic physical models.
GPU-accelerated full-field modelling of highly dispersive ultrafast optical parametric oscillators
Authors: Robarts Sebastian C. , Hunter Diana E. , Reid Derryck T. , McCracken Richard A. 
Published: November 2023

We demonstrate GPU-accelerated modelling of ultrafast optical parametric oscillators (OPOs) via the χ(2) nonlinear envelope equation with 1265× improvement in execution time compared with a CPU-based approach. Incorporating an adaptive step-size algorithm and absorbing boundary conditions, our model is capable of simulating OPOs containing long (>10 mm) nonlinear crystals or significant intracavity dispersion with outputs generated in less than 1 minute, allowing the investigation of systems that were previously computationally prohibitive to explore. We implement real-world parameters such as optical coatings, material absorption, and non-ideal poling domains within quasi-phase matched nonlinear crystals, producing excellent agreement with the spectral tuning behaviour and average power from a previously reported prism-based OPO. Our digital twinning approach provides a low-cost iterative development platform for ultrafast OPOs.
Epidemiology of intestinal helminthiasis with an emphasis on taeniasis in Chipata district of the Eastern province of Zambia
Authors: Zulu Gideon , Sikasunge Chummy S. , Welte Tamara M. , Simuunza Martin C. , Stelzle Dominik , Schmidt Veronika , Hachangu Alex , Mutale Wilbroad , Masuku Maxwell , Chembensofu Mwelwa , da Costa Clarissa Prazeres , Mwape Kabemba E. , Winkler Andrea S. , Phiri Isaac K. 
Published: November 2023

Background
Intestinal helminth infections are among the most common infections worldwide and have a negative impact on the health, education, nutrition and economic development of affected populations. This study aimed to estimate the prevalence of intestinal helminthiasis, including T. solium taeniasis, using a large-scale community-based study in Chiparamba area of Chipata District in the Eastern province of Zambia.

Methods/Principal findings
A cross-sectional study was conducted between June 2019 and December 2022 in a rural community of 25 randomly selected villages known to be at risk for T. solium infection. Stool samples were examined for intestinal helminths using the formol-ether concentration technique and further tested for taeniasis by copro antigen-ELISA (copro Ag-ELISA). Descriptive statistical analyses were conducted, and associations between the disease prevalence of active infections and individual- and village-level variables were determined using the chi-square or Fisher’s exact test. Predictors of an individual being positive for either taeniasis or other soil-transmitted helminths were determined using binary logistic regression. A total of 2762 stool samples were examined. One hundred ninety-five (7.1%) tested positive for at least one helminthic parasite on microscopy, with hookworm being the most frequent 84 (3.0%), followed by S. mansoni, 66 (2.4%). For taeniasis, 11 (0.4%) participants were positive for Taenia spp. microscopically, while 241 (8.7%) tested positive via copro Ag-ELISA. On bivariate analysis, male sex was significantly associated with the prevalence of intestinal parasites (p = 0.012) but not with that of taeniasis based on copro Ag-ELISA results. Village level differences were significant for infection with intestinal helminths as well as for taeniasis positivity on copro Ag-ELISA (p <0.001).

Conclusion
Intestinal helminths, including T. solium taeniasis, are prevalent in Chiparamba area of Chipata district in the eastern province of Zambia, supporting the clear need for further targeted public health interventions for surveillance and control.
Patient experiences with SARS-CoV-2: Associations between patient experience of disease and coping profiles
Authors: Hendrickson Kathryn W. , Hopkins Ramona O. , Groat Danielle L. , Stokes Stephanie C. , Schroeder Fiona M. , Butler Jorie M. , Hirshberg Eliotte L. 
Published: November 2023

Introduction
Severe acute respiratory syndrome coronavirus 2, (SARS-CoV-2,) caused an influx of patients with acute disease characterized by a variety of symptoms termed COVID-19 disease, with some patients going on to develop post-acute COVID-19 syndrome. Individual factors like sex or coping styles are associated with a person’s disease experience and quality of life. Individual differences in coping styles used to manage COVID-19 related stress correlate with physical and mental health outcomes. Our study sought to understand the relationship between COVID-19 symptoms, severity of acute disease, and coping profiles.

Methods
An online survey to assess symptoms, functional status, and recovery in a large group of patients was nationally distributed online. The survey asked about symptoms, course of illness, and included the Brief-COPE and the adapted Social Relationship Inventory. We used descriptive and cluster analyses to characterize patterns of survey responses.

Results
976 patients were included in the analysis. The most common symptoms reported by the patients were fatigue (72%), cough (71%), body aches/joint pain (66%), headache (62%), and fever/chills (62%). 284 participants reported PACS. We described three different coping profiles: outward, inward, and dynamic copers.

Discussion
Fatigue, cough, and body aches/joint pains were the most frequently reported symptoms. PACS patients were sicker, more likely to have been hospitalized. Of the three coping profiles, outward copers were more likely to be admitted to the hospital and had the healthiest coping strategies. Dynamic copers activated several coping strategies both positive and negative; they were also younger and more likely to report PACS.

Conclusion
Cough, fatigue, and body aches/joint pain are common and most important to patients with acute COVID-19, while shortness of breath defined the experience for patients with PACS. Of the three coping profiles, dynamic copers were more likely to report PACS. Additional investigations into coping profiles in general, and the experience of COVID-19 and PACS is needed.
Working conditions of the clinical health workforce in the public health facilities in Bangladesh
Authors: Hamid Syed Abdul , Azim Md. Ragaul , Rahman Md. Mahfujur , Islam Md. Sirajul 
Published: November 2023

Background
The COVID-19 pandemic has highlighted the importance of a well-equipped and supported healthcare workforce, and Bangladesh still faces challenges in providing adequate and well-equipped healthcare services. Therefore, the study aims to assess the level of working conditions of the clinical health workers in Bangladesh and their relative importance in delivering quality healthcare services.

Methods
The study followed a cross-sectional study design and collected primary data adopting a quantitative method. A total of 319 clinical workforces from four districts and eight sub-districts were randomly selected using a multi-stage sampling technique. A 26-component questionnaire used to assess various components of working conditions. Descriptive statistics, and bivariate analysis were used to analyze the data.

Results
The study found that the working conditions of clinical health workers in primary and secondary healthcare facilities in Bangladesh were quite poor (3.40), with almost two-thirds of respondents showing negative views in 23 out of 26 indicators. The results also showed that working conditions were significantly (p ≤ 0.05) higher in primary compared to secondary level facilities. Moreover, men, younger workforce, and workforce with shorter length of service were more likely to report poor working conditions than their counterparts. Lastly, receiving monthly salary in due time was top-ranked (99.15) in terms of importance for delivering quality healthcare, followed by availability of medicines (98.04), and medical and surgical requisites (97.57), and adequate mentoring and support to perform duties (97.50).

Conclusion
The study highlights the poor working conditions of clinical health workers in public health facilities in Bangladesh. It recommends that policymakers should prioritize improving working conditions by addressing the factors that are crucial for delivering quality healthcare. Improving working conditions will have a positive impact on the retention and motivation of workers, which will ultimately lead to better health outcomes for the population.
Long-term efficacy of transanal local excision versus total mesorectal excision after neoadjuvant treatment for rectal cancer: A meta-analysis
Authors: Lei Yihui , Lin Li , Shao Qiming , Chen Weiping , Liu Guoyan 
Published: November 2023

Aim
The purpose of this meta-analysis is to compare the long-term efficacy of transanal local excision (TLE) versus total mesorectal excision (TME) following neoadjuvant therapy for rectal cancer.

Method
The Web of Science, Pubmed, Medline, Embase, and the Cochrane Library were systematically searched for correlational research. The Newcastle-Ottawa Scale and the Cochrane risk of bias tool were used to assess the quality of cohort studies (CSs) and randomized controlled trials (RCTs), respectively. Statistically analyzed using RevMan5.4.

Result
A total of 13 studies, including 3 randomized controlled trials (RCTs) and 10 cohort studies (CSs), involving 1402 patients, were included in the analysis. Of these, 570 patients (40.66%) underwent TLE, while 832 patients (59.34%) underwent TME. In the meta-analysis of CSs, no significant difference was observed between the TLE group and TME group regarding 5-year overall survival (OS) and 5-year disease-free survival (DFS) (P > 0.05). However, the TLE group had a higher rates of local recurrence (LR) [risk ratio (RR) = 1.93, 95%CI (1.18, 3.14), P = 0.008] and a lower rates of 5-years local recurrence-free survival (LRFS) [hazard ratio (HR) = 2.79, 95%CI (1.04, 7.50), P = 0.04] compared to the TME group. In the meta-analysis of RCTs, there was no significant difference observed between the TLE group and TME group in terms of LR, 5-year OS, 5-year DFS, and 5-year disease-specific survival (P > 0.05).

Conclusion
After undergoing neoadjuvant therapy, TLE may provide comparable 5-year OS and DFS to TME for rectal cancer. However, neoadjuvant therapy followed by TLE may has a higher LR and lower 5-year LRFS compared to neoadjuvant therapy followed by TME, so patients should be carefully selected. Neoadjuvant therapy followed by TLE may be a suitable option for patients who prioritize postoperative quality of life. However, the effectiveness of this approach requires further research to draw a definitive conclusion.
Intravenous acetaminophen for postoperative pain in the neonatal intensive care unit: A protocol for a pilot randomized controlled trial (IVA POP)
Authors: Archer Victoria Anne , Samiee-Zafarghandy Samira , Farrokyhar Forough , Briatico Daniel , Braga Luis H. , Walton J. Mark 
Published: November 2023

Background
In neonates, uncontrolled pain and opioid exposure are both correlated with short- and long-term adverse events. Therefore, managing pain using opioid-sparing approaches is critical in neonatal populations. Multimodal pain control offers the opportunity to manage pain while reducing short- and long-term opioid-related adverse events. Intravenous (IV) acetaminophen may represent an appropriate adjunct to opioid-based postoperative pain control regimes. However, no trials assess this drug in patients less than 36 weeks post-conceptual age or weighing less than 1500 g.

Objective
The proposed study aims to determine the feasibility of conducting a randomized control trial to compare IV acetaminophen and fentanyl to a saline placebo and fentanyl for patients admitted to the neonatal intensive care unit (NICU) undergoing major abdominal or thoracic surgery.

Methods and design
This protocol is for a single-centre, external pilot randomized controlled trial (RCT). Infants in the NICU who have undergone major thoracic or abdominal surgery will be enrolled. Sixty participants will undergo 1:1 randomization to receive intravenous acetaminophen and fentanyl or saline placebo and fentanyl. After surgery, IV acetaminophen or placebo will be given routinely for eight days (192 hours). Appropriate dosing will be determined based on the participant’s gestational age. Patients will be followed for eight days after surgery and will undergo a chart review at 90 days. Primarily feasibility outcomes include recruitment rate, follow-up rate, compliance, and blinding index. Secondary clinical outcomes will be collected as well.

Conclusion
This external pilot RCT will assess the feasibility of performing a multicenter RCT comparing IV acetaminophen and fentanyl to a saline placebo and fentanyl in NICU patients following major abdominal and thoracic surgery. The results will inform the design of a multicenter RCT, which will have the appropriate power to determine the efficacy of this treatment.

Trial registration
ClinicalTrials.gov NCT05678244, Registered December 6, 2022.
Interdisciplinary interventions that improve patient-reported outcomes in perioperative cancer care: A systematic review of randomized control trials
Authors: Maheta Bhagvat J. , Singh Nainwant K. , Lorenz Karl A. , Fereydooni Sarina , Dy Sydney M. , Wong Hong-nei , Bergman Jonathan , Leppert John T. , Giannitrapani Karleen F. 
Published: November 2023

Introduction
Interdisciplinary teams are often leveraged to improve quality of cancer care in the perioperative period. We aimed to identify the team structures and processes in interdisciplinary interventions that improve perioperative patient-reported outcomes for patients with cancer.

Methods
We searched PubMed, EMBASE, and CINAHL for randomized control trials published at any time and screened 7,195 articles. To be included in our review, studies needed to report patient-reported outcomes, have interventions that occur in the perioperative period, include surgical cancer treatment, and include at least one non physician intervention clinical team member: advanced practice providers, including nurse practitioners and physician assistants, clinical nurse specialists, and registered nurses. We narratively synthesized intervention components, specifically roles assumed by intervention clinical team members and interdisciplinary team processes, to compare interventions that improved patient-reported outcomes, based on minimal clinically important difference and statistical significance.

Results
We included 34 studies with a total of 4,722 participants, of which 31 reported a clinically meaningful improvement in at least one patient-reported outcome. No included studies had an overall high risk of bias. The common clinical team member roles featured patient education regarding diagnosis, treatment, coping, and pain/symptom management as well as postoperative follow up regarding problems after surgery, resource dissemination, and care planning. Other intervention components included six or more months of continuous clinical team member contact with the patient and involvement of the patient’s caregiver.

Conclusions
Future interventions might prioritize supporting clinical team members roles to include patient education, caregiver engagement, and clinical follow-up.