bluuebunny/crossref_metadata_2025_split huggingface dataset:
Common Neural Mechanisms for Response Selection and Perceptual Processing
Authors: Jiang Yuhong , Kanwisher Nancy 
Published: December 2003

Abstract
Behavioral evidence supports a dissociation between response selection (RS; stimulus-to-response [S—R] mapping) and perceptual discrimination (PD): The former may be subject to a central processing bottleneck, whereas the latter is not (Pashler, 1994). We previously (Jiang & Kanwisher, 2003) identified a set of frontal and parietal regions involved in RS as those that produce a stronger signal when subjects follow a difficult S—R mapping rule than an easy mapping rule. Here, we test whether any of these regions are selectively activated by RS and not perceptual processing, as predicted by the central bottleneck view. In Experiment 1, subjects indicated which of four parallel lines was unique in length; PD was indexed by a higher BOLD response when the discrimination was difficult versus easy. Stimuli and responses were closely matched across conditions. We found that all regions-of-interest (ROIs) engaged by RS were also engaged by perceptual processing, arguing against the existence of mechanisms exclusively involved in RS. In Experiments 2 and 3, we asked what processes might go on in these ROIs, such that they could be recruited by both RS and perceptual processing. Our data argue against an account of this common activation in terms of spatial processing or general task difficulty. Thus, PD may recruit the same central processes that are engaged by RS.
Neural Evidence for Representation-Specific Response Selection
Authors: Schumacher Eric H. , Elston Puni A. , D'Esposito Mark 
Published: December 2003

AbstractResponse selection is the mental process of choosing representations for appropriate motor behaviors given particular environmental stimuli and one's current task situation and goals. Many cognitive theories of response selection postulate a unitary process. That is, one central response-selection mechanism chooses appropriate responses in most, if not all, task situations. However, neuroscience research shows that neural processing is often localized based on the type of information processed. Our current experiments investigate whether response selection is unitary or stimulus specific by manipulating response-selection difficulty in two functional magnetic resonance imaging experiments using spatial and nonspatial stimuli. The same participants were used in both experiments. We found spatial response selection involves the right prefrontal cortex, the bilateral premotor cortex, and the dorsal parietal cortical regions (precuneus and superior parietal lobule). Nonspatial response selection, conversely, involves the left prefrontal cortex and the more ventral posterior cortical regions (left middle temporal gyrus, left inferior parietal lobule, and right extrastriate cortex). Our brain activation data suggest a cognitive model for response selection in which different brain networks mediate the choice of appropriate responses for different types of stimuli. This model is consistent with behavioral research suggesting that responseselection processing may be more flexible and adaptive than originally proposed.
Working Memory for Complex Scenes: Age Differences in Frontal and Hippocampal Activations
Authors: Park Denise C. , Welsh Robert C. , Marshuetz Christy , Gutchess Angela H. , Mikels Joseph , Polk Thad A. , Noll Douglas C. , Taylor Stephan F. 
Published: December 2003

Abstract
Age differences in frontal and hippocampal activations in working memory were investigated during a maintenance and subsequent probe interval in an event-related fMRI design. Younger and older adults either viewed or maintained photographs of real-world scenes (extended visual or maintenance conditions) over a 4-sec interval before responding to a probe fragment from the studied picture. Behavioral accuracy was largely equivalent across age and conditions on the probe task, but underlying neural activations differed. Younger but not older adults showed increased left anterior hippocampal activations in the extended visual compared with the maintenance condition. Onthesubsequent probeinterval, however, older adultsshowed more left and right inferior frontal activations than younger adults. The increased frontal activations at probe in older adults may have been compensatory for the decreased hippocampal activations during maintenance, but alternatively could have reflected the increased difficulty of the probe task for the older subjects. Thus, we demonstrate qualitatively different engagement of both frontal and hippocampal structures in older adults in a working memory task, despite behavioral equivalence.
ERP Evidence for a Sex-Specific Stroop Effect in Emotional Speech
Authors: Schirmer Annett , Kotz Sonja A. 
Published: December 2003

Abstract
The present study investigated the interaction of emotional prosody and word valence during emotional comprehension in men and women. In a prosody-word interference task, participants listened to positive, neutral, and negative words that were spoken with a happy, neutral, and angry prosody. Participants were asked to rate word valence while ignoring emotional prosody, or vice versa. Congruent stimuli were responded faster and more accurately as compared to incongruent emotional stimuli. This behavioral effect was more salient for the word valence task than for the prosodic task and was comparable between men and women. The event-related potentials (ERPs) revealed a smaller N400 amplitude for congruent as compared to emotionally incongruent stimuli. This ERP effect, however, was significant only for the word valence judgment and only for female listeners. The present data suggest that the word valence judgment was more difficult and more easily influenced by task-irrelevant emotional information than the prosodic task in both men and women. Furthermore, although emotional prosody and word valence may have a similar influence on an emotional judgment in both sexes, ERPs indicate sex differences in the underlying processing. Women, but not men, show an interaction between prosody and word valence during a semantic processing stage.
Processing Tonal Modulations: An ERP Study
Authors: Koelsch Stefan , Gunter Thomas , Schröger Erich , Friederici Angela D. 
Published: December 2003

Abstract
A common stylistic element of Western tonal music is the change of key within a musical sequence (known as modulation in musical terms). The aim of the present study was to investigate neural correlates of the cognitive processing of modulations with event-related brain potentials. Participants listened to sequences of chords that were infrequently modulating. Modulating chords elicited distinct effects in the event-related brain potentials: an early right anterior negativity reflecting the processing of a violation of musical regularities and a late frontal negativity taken to reflect processes of harmonic integration. Additionally, modulations elicited a tonic negative potential suggested to reflect cognitive processes characteristic for the processing of tonal modulations, namely, the restructuring of the “hierarchy of harmonic stability” (which specifies musical expectations), presumably entailing working memory operations. Participants were “nonmusicians”; results thus support the hypothesis that nonmusicians have a sophisticated (implicit) knowledge about musical regularities.
An Event-Related fMRI Investigation of Implicit Semantic Priming
Authors: Rissman Jesse , Eliassen James C. , Blumstein Sheila E. 
Published: December 2003

Abstract
The neural basis underlying implicit semantic priming was investigated using event-related fMRI. Prime-target pairs were presented auditorily for lexical decision (LD) on the target stimulus, which was either semantically related or unrelated to the prime, or was a nonword. A tone task was also administered as a control. Behaviorally, all participants demonstrated semantic priming in the LD task. fMRI results showed that for all three conditions of the LD task, activation was seen in the superior temporal gyrus (STG), the middle temporal gyrus (MTG), and the inferior parietal lobe, with greater activation in the unrelated and nonword conditions than in the related condition. Direct comparisons of the related and unrelated conditions revealed foci in the left STG, left precentral gyrus, left and right MTGs, and right caudate, exhibiting significantly lower activation levels in the related condition. The reduced activity in the temporal lobe suggests that the perception of the prime word activates a lexical— semantic network that shares common elements with the target word, and, thus, the target can be recognized with enhanced neural efficiency. The frontal lobe reductions most likely reflect the increased efficiency in monitoring the activation of lexical representations in the temporal lobe, making a decision, and planning the appropriate motor response.
Orienting Attention to Locations in Internal Representations
Authors: Griffin Ivan C. , Nobre Anna C. 
Published: December 2003

Abstract
Three experiments investigated whether it is possible to orient selective spatial attention to internal representations held in working memory in a similar fashion to orienting to perceptual stimuli. In the first experiment, subjects were either cued to orient to a spatial location before a stimulus array was presented (pre-cue), cued to orient to a spatial location in working memory after the array was presented (retro-cue), or given no cueing information (neutral cue). The stimulus array consisted of four differently colored crosses, one in each quadrant. At the end of a trial, a colored cross (probe) was presented centrally, and subjects responded according to whether it had occurred in the array. There were equivalent patterns of behavioral costs and benefits of cueing for both pre-cues and retro-cues. A follow-up experiment used a peripheral probe stimulus requiring a decision about whether its color matched that of the item presented at the same location in the array. Replication of the behavioral costs and benefits of pre-cues and retro-cues in this experiment ruled out changes in response criteria as the only explanation for the effects. The third experiment used event-related potentials (ERPs) to compare the neural processes involved in orienting attention to a spatial location in an external versus an internal spatial representation. In this task, subjects responded according to whether a central probe stimulus occurred at the cued location in the array. There were both similarities and differences between ERPs to spatial cues toward a perception versus an internal spatial representation. Lateralized early posterior and later frontal negativities were observed for both preand retro-cues. Retro-cues also showed additional neural processes to be involved in orienting to an internal representation, including early effects over frontal electrodes.
Grammar Processing Outside the Focus of Attention: an MEG Study
Authors: Shtyrov Yury , Pulvermüller Friedemann , Näätänen Risto , Ilmoniemi Risto J. 
Published: December 2003

AbstractTo address the cerebral processing of grammar, we used whole-head high-density magnetoencephalography to record the brain's magnetic fields elicited by grammatically correct and incorrect auditory stimuli in the absence of directed attention to the stimulation. The stimuli were minimal short phrases of the Finnish language differing only in one single phoneme (word-final inflectional affix), which rendered them as either grammatical or ungrammatical. Acoustic and lexical differences were controlled for by using an orthogonal design in which the phoneme's effect on grammaticality was inverted. We found that occasional syntactically incorrect stimuli elicited larger mismatch negativity (MMN) responses than correct phrases. The MMN was earlier proposed as an index of preattentive automatic speech processing. Therefore, its modulation by grammaticality under nonattend conditions suggests that early syntax processing in the human brain may take place outside the focus of attention. Source analysis (single—dipole models and minimum-norm current estimates) indicated grammaticality dependent differential activation of the left superior temporal cortex suggesting that this brain structure may play an important role in such automatic grammar processing.
Direct Evidence for a Binding between Cognitive and Motor Functions in Humans: A TMS Study
Authors: Bonnard Mireille , Camus Mickael , de Graaf Jozina , Pailhous Jean 
Published: December 2003

Abstract
During voluntary motor actions, the cortico-spinal (CS) excitability is known to be modulated, on the one hand by cognitive (intention-related) processes and, on the other hand, by motor (performance-related) processes. Here, we studied the way these processes interact in the tuning of CS excitability during voluntary wrist movement. We used transcranial magnetic stimulation (TMS) both as a reliable tool for quantifying the CS excitability, through the motor-evoked potentials (MEPs), and as a central perturbation evoking a movement (because the stimulation intensity was above threshold) with subjects instructed to prepare (without changing their muscle activation) either to “let go” or to “resist” to this evoked movement. We studied the simultaneous evolution of both the motor performance and the MEPs in the wrist flexor and extensor, separately for the successful trials (on average, 66% of the trials whatever the condition) and the unsuccessful trials; this allowed us to dissociate the intentionand performance-related processes. To their great surprise, subjects were found able to cognitively prepare themselves to resist a TMS-induced central perturbation; they all reported an important cognitive effort on the evoked movement. Moreover, because TMS only evoked short-latency MEPs (and no long-latency components), the amplitude of these short-latency MEPs was found to be related in a continuous way to the actual movement whatever the prior intention. These results demonstrate that prior intention allows an anticipatory modulation of the CS excitability, which is not only selective (as already known) but also efficient, giving the intended motor behavior a real chance to be realized. This constitutes a direct evidence of the role of the CS excitability in the binding between cognitive and motor processes in humans.
A Monotonic Code for Sound Azimuth in Primate Inferior Colliculus
Authors: Groh Jennifer M. , Kelly Kristin A. , Underhill Abigail M. 
Published: December 2003

Abstract
We investigated the format of the code for sound location in the inferior colliculi of three awake monkeys (Macaca mulatta). We found that roughly half of our sample of 99 neurons was sensitive to the free-field locations of broadband noise presented in the frontal hemisphere. Such neurons nearly always responded monotonically as a function of sound azimuth, with stronger responses for more contralateral sound locations. Few, if any, neurons had circumscribed receptive fields. Spatial sensitivity was broad: the proportion of the total sample of neurons responding to a sound at a given location ranged from 30% for ipsilateral locations to 80% for contralateral locations. These findings suggest that sound azimuth is represented via a population rate code of very broadly responsive neurons in primate inferior colliculi. This representation differs in format from the place code used for encoding the locations of visual and tactile stimuli and poses problems for the eventual convergence of auditory and visual or somatosensory signals. Accordingly, models for converting this representation into a place code are discussed.
Spatial and Temporal Sequence Learning in Patients with Parkinson's Disease or Cerebellar Lesions
Authors: Shin Jacqueline C. , Ivry Richard B. 
Published: December 2003

AbstractThe functional role of different subcortical areas in sequence learning is not clear. In the current study, Parkinson's patients, patients with cerebellar damage, and age-matched control participants performed a serial reaction time task in which a spatial sequence and a temporal sequence were presented simultaneously. The responses were based on the spatial sequence, and the temporal sequence was incidental to the task. The two sequences were of the same length, and the phase relationship between them was held constant throughout training. Sequence learning was assessed comparing performance when both sequences were present versus when the dimension of interest was randomized. In addition, sequence integration was assessed by introducing phase-shift blocks. A functional dissociation was found between the two patient groups. Whereas the Parkinson's patients learned the spatial and temporal sequences individually, they did not learn the relationship between the two sequences, suggesting the basal ganglia play a functional role in sequence integration. In contrast, the cerebellar patients did not show any evidence of sequence learning at all, suggesting the cerebellum might play a general role in forming sequential associations.
Precise Oculomotor Correlates of Visuospatial Mental Rotation and Circular Motion Imagery
Authors: de'Sperati Claudio 
Published: December 2003

Abstract
Visual imagery is a basic form of cognition central to activities such as problem solving or creative thinking. Phenomena such as mental rotation, in which mental images undergo spatial transformations, and motion imagery, in which we imagine objects in motion, are very elusive. For example, although several aspects of visual imagery and mental rotation have been reconstructed through mental chronometry, their instantaneous evolution has never been directly observed. We paired mental chronometry to eye movement recording in subjects performing a visuospatial mental rotation task and an instructed circular motion imagery task. In both tasks, sequences of spontaneous saccades formed curved trajectories with a regular spatio-temporal evolution. In the visuospatial mental rotation task, saccadic amplitude decreased progressively within each sequence, resulting in an average gaze rotation with a bell-shaped asymmetrical angular velocity profile whose peak and mean increased with the amount of the to-be-performed rotation, as in reaching movements. In the second task, the average gaze rotation reproduced faithfully the to-be-imagined constant-velocity circular motion, thus excluding important distortions in the oculomotor performance. These findings show for the first time the instantaneous spatio-temporal evolution of mental rotation and motion imagery. Moreover, the fact that visuospatial mental rotation is modeled as a reaching act suggests that reaching pertains to the realm of visuospatial thinking, rather than being restricted to the motor domain. This approach based on eye movement recording can be profitably coupled to methods such as event-related potentials, transcranial magnetic stimulation, or functional magnetic resonance to study the precise neuronal dynamics associated with an ongoing mental activity.
Victims and the International Criminal Court: Three major issues
Authors: Garkawe Sam 
Published: December 2003

AbstractThe Statute of the permanent International Criminal Court (the "ICC") agreed to in Rome in 1998 contains many provisions that deal with the specific concerns and rights of victims and survivors of the international crimes that the ICC will have jurisdiction over. It consolidates the work of the two ad hoc international criminal Tribunals (the former Yugoslavia and Rwanda) in this area, but also further enhances the role and rights of victims in a number of innovative ways. These three international criminal Tribunals thus collectively represent an important step forward in the recognition of the suffering and the position of victims and survivors of international crimes. This article will examine three main issues in relation to victims and the ICC. First, after identifying the protective measures for victims allowed at the discretion of the international criminal Tribunal for the former Yugoslavia, it will focus on the most controversial measure (which the ICC can also order) - the non-disclosure to the defence of the identity of witnesses. Does this protective measure violate a defendant's right to a fair trial? The Statute of the ICC also allows, for the first time in international criminal justice, for the right of victims to obtain their own legal representation, subject to the discretion of the ICC. The second issue is how is this going to work in practice in light of the fact that international crimes normally involve hundreds, if not thousands or even tens of thousands, of victims? And finally, while the ICC Statute provides for the possibility of reparations to victims, where will the money come from, and thus what are the chances of victims actually being able to receive compensation?
The doctrine of Res Judicata in International Criminal Law
Authors: Theofanis Rosa 
Published: December 2003

AbstractRes judicata is well-settled as a general principle of international law. But the rules of res judicata in international criminal procedure are undeveloped. Recent cases from the ad hoc criminal tribunals for the former Yugoslavia and Rwanda have added to the understanding of res judicata in international law - demonstrating the risk that new rules of res judicata will implicitly incorporate either a common-law or civil-law definition of what the "law" is. Analysis of issues considered in recent Tribunal jurisprudence - particularly the questions of review and reconsideration - locates potential hazards in the development of the law and provides guidance for the application of the ICC statute.