bluuebunny/crossref_metadata_2025_split huggingface dataset:
“We touch their heart”: Plastic Automaticity and Affective Labour at Jakarta Soekarno‐Hatta Airport
Authors: Adey Peter , Lin Weiqiang , Harris Tina 
Published: January 2024

AbstractLabour research in geography has long been fascinated with the role of affects and emotions in capitalism. This article foregrounds ambivalent moments when labour creatively uses affection and intimacy to make claims over autonomy and agency. Set against a backdrop of increasing automation of infrastructural work, we draw on interviews with personnel at Jakarta Soekarno‐Hatta Airport (CGK). In culturally situating these automations, we evince how the “heart” (or the Indonesian notion of curahan hati), with semblances to customer‐facing labour management practices, and other affective dispositions under neoliberal life, is repeatedly deployed to “fill in the gaps” for where automation may fail. We illuminate how these workers navigate wearying, uncertain, and demanding facilitation, security, and customer service situations by emphasising “heart‐to‐heart” relations, even as they stave off technology's encroachments (and withdrawals). This plastic automaticity offers a template by which the pressures of capital's technologisation could be relieved, beyond emotional labour.
The role of cold ischemia time and hypothermic perfusion in predicting early hepatocellular carcinoma recurrences after liver transplantation
Authors: Dajti Gerti , Germinario Giuliana , Prosperi Enrico , Siniscalchi Antonio , Vasuri Francesco , Valente Sabrina , Odaldi Federica , Maroni Lorenzo , Serenari Matteo , Bertuzzo Valentina , Laurenzi Andrea , del Gaudio Massimo , Cescon Matteo , Ravaioli Matteo 
Published: January 2024

AbstractAimThe aim of the study was to identify predictors of early tumor recurrence in patients with hepatocellular carcinoma (HCC) after liver transplantation (LT).MethodsRetrospective cohort study in 237 consecutive liver recipients with HCC between 2016 and 2021. Multivariate logistic analysis was performed to identify predictors of early HCC recurrences. The impact of hypothermic‐oxygenated perfusion (HOPE) on outcome was analyzed after propensity score weighting.ResultsEarly recurrences were observed in 15 cases. Microvascular invasion (OR 3.737, 95% CI 1.246–11.206, p = 0.019) and cold ischemia time (OR 1.155, 95% CI 1.001–1.333, p = 0.049) were independently associated with a lower risk of HCC recurrences. After balancing for relevant variables, patients in the HOPE group had lower rates of tumor recurrence (weighted OR 0.126, 95% CI 0.016–0.989, p = 0.049) and higher recurrence free survival (weighted HR 0.132, 95% CI 0.017–0.999, p = 0.050).ConclusionReducing cold ischemia time and graft perfusion with HOPE can lead to lower rates of early HCC recurrences and higher recurrence‐free survival.
Erythrocyte metabolism
Authors: Chatzinikolaou Panagiotis N. , Margaritelis Nikos V. , Paschalis Vassilis , Theodorou Anastasios A. , Vrabas Ioannis S. , Kyparos Antonios , D'Alessandro Angelo , Nikolaidis Michalis G. 
Published: January 2024

AbstractOur aim is to present an updated overview of the erythrocyte metabolism highlighting its richness and complexity. We have manually collected and connected the available biochemical pathways and integrated them into a functional metabolic map. The focus of this map is on the main biochemical pathways consisting of glycolysis, the pentose phosphate pathway, redox metabolism, oxygen metabolism, purine/nucleoside metabolism, and membrane transport. Other recently emerging pathways are also curated, like the methionine salvage pathway, the glyoxalase system, carnitine metabolism, and the lands cycle, as well as remnants of the carboxylic acid metabolism. An additional goal of this review is to present the dynamics of erythrocyte metabolism, providing key numbers used to perform basic quantitative analyses. By synthesizing experimental and computational data, we conclude that glycolysis, pentose phosphate pathway, and redox metabolism are the foundations of erythrocyte metabolism. Additionally, the erythrocyte can sense oxygen levels and oxidative stress adjusting its mechanics, metabolism, and function. In conclusion, fine‐tuning of erythrocyte metabolism controls one of the most important biological processes, that is, oxygen loading, transport, and delivery.
The mediating effect of institutional trust in the relationship between precarity and conspiracy beliefs: A conceptual replication of Adam‐Troian et al. (2023)
Authors: Adamus Magdalena , Ballová Mikušková Eva , Kačmár Pavol , Guzi Martin , Adamkovič Matuš , Chayinska Maria , Adam‐Troian Jais 
Published: January 2024

AbstractThe paper reports the results of registered conceptual replications of the indirect effect of institutional trust in the relationship between precarity and the endorsement of conspiracy beliefs (CB). The original study of Adam‐Troian et al. (2023; British Journal of Social Psychology, 62(S1), 136‐159) indicated that subjective appraisals of economic hardship are associated with lower trust in governments and institutions, which in turn is associated with stronger endorsement of CB. Our Studies 1 to 3 report a series of replications using Slovak panel data. Study 4 reports a replication of the mediation model using data from the European Social Survey Round 10 collected in 17 countries. To provide a quantitative synthesis of these and previous results, we conducted mini meta‐analysis (N = 50,340). Although the strength of the observed relationships differed across the studies to some degree, the original patterns of relations remained robust, supporting the original model. The study corroborates the view that to curb the spread of CB, it is necessary to address structural issues, such as growing financial insecurity, socioeconomic inequalities, and the deficit of institutional trust. Finally, we discuss the role of cultural and political settings in conditioning the mechanisms through which precarity enhances the endorsement of CB.
Business risk management programs and the adoption of beneficial management practices in Canadian crop agriculture
Authors: De Laporte Aaron , Schuurman Daniel , Skolrud Tristan , Slade Peter , Weersink Alfons 
Published: January 2024

AbstractCanada's agricultural business risk management (BRM) programs require significant public expenditure, with unclear consequences related to climate change adaptation and mitigation through the adoption of beneficial management practices (BMPs). This study examines the relationship between Canada's current suite of BRM programs and the adoption of practices that mitigate GHG emissions in crop agriculture. We review the impacts of agricultural insurance on climate adaptation and mitigation, identifying impacts on both the intensive and extensive margins of production. We consider five potential program modifications, including: (1) changes in producer insurance premiums in AgriInsurance for the adoption of practices that would decrease the actuarially fair insurance rate if they were properly incorporated in the calculation; (2) dedicated insurance products related to trials of specific BMPs; (3) adjustments to current programs to allow more whole‐farm considerations and intercropping; (4) cross‐compliance measures on AgriInvest tied to environmental education; and (5) reduced insurance coverage for unfavorable environmental practices. While the effects of these potential modifications remain uncertain, they will drive the data collection process necessary to ensure that Canada's BRM programs play an appropriate role in greenhouse‐gas reducing BMP adoption and climate change adaptation and mitigation.
Efficacy of a benzothiazole‐based LRRK2 inhibitor in oligodendrocyte precursor cells and in a murine model of multiple sclerosis
Authors: Benítez‐Fernández Rocío , Josa‐Prado Fernando , Sánchez Estefanía , Lao Yolanda , García‐Rubia Alfonso , Cumella José , Martínez Ana , Palomo Valle , de Castro Fernando 
Published: January 2024

AbstractAimsMultiple sclerosis (MS) is a chronic neurological disease that currently lacks effective curative treatments. There is a need to find effective therapies, especially to reverse the progressive demyelination and neuronal damage. Oligodendrocytes form the myelin sheath around axons in the central nervous system (CNS) and oligodendrocyte precursor cells (OPCs) undergo mechanisms that enable spontaneously the partial repair of damaged lesions. The aim of this study was to discover small molecules with potential effects in demyelinating diseases, including (re)myelinating properties.MethodsRecently, it has been shown how LRRK2 inhibition promotes oligodendrogliogenesis and therefore an efficient repair or myelin damaged lesions. Here we explored small molecules inhibiting LRRK2 as potential enhancers of primary OPCs proliferation and differentiation, and their potential impact on the clinical score of experimental autoimmune encephalomyelitys (EAE) mice, a validated model of the most frequent clinical form of MS, relapsing–remitting MS.ResultsOne of the LRRK2 inhibitors presented in this study promoted the proliferation and differentiation of OPC primary cultures. When tested in the EAE murine model of MS, it exerted a statistically significant reduction of the clinical burden of the animals, and histological evidence revealed how the treated animals presented a reduced lesion area in the spinal cord.ConclusionsFor the first time, a small molecule with LRRK2 inhibition properties presented (re)myelinating properties in primary OPCs cultures and potentially in the in vivo murine model. This study provides an in vivo proof of concept for a LRRK2 inhibitor, confirming its potential for the treatment of MS.
Benchmarking fish biodiversity of seaports with eDNA and nearby marine reserves
Authors: Manel Stéphanie , Mathon Laetitia , Mouillot David , Bruno Morgane , Valentini Alice , Lecaillon Gilles , Gudefin Anais , Deter Julie , Boissery Pierre , Dalongeville Alicia 
Published: January 2024

AbstractCoastal areas offer a diversity of habitats providing refugia and nursery for fish, promoting their biodiversity and associated contributions to people. Yet, natural coastlines are replaced by artificial infrastructures such as seaports and the influence of this artificialization on fish biodiversity remains poorly known. Here, we assessed fish biodiversity indicators using environmental DNA metabarcoding inside seaports and adjacent natural habitats including no‐take marine reserves. We found that species assemblages within seaports were primarily influenced by their area and habitat. We detected a similar species richness in seaports and reserves during lockdown, but seaports host more threatened species than natural habitats. Yet, species turnover between seaports was lower than between natural areas, reflecting biotic homogenization. Seaport managers should consider that complexifying artificial infrastructures could increase habitat diversity and coastal fish biodiversity. Our study illustrates that eDNA‐based indicators can be integrated in management and policy applications toward greener marine artificial infrastructures.
Combating the exotic pet trade: Effects of conservation messaging on attitudes, demands, and civic intentions
Authors: Naito Rumi , Chan Kai M. A. , Zhao Jiaying 
Published: January 2024

AbstractThe exotic pet trade poses a major threat to biodiversity conservation. To combat biodiversity loss, it is essential to reduce demand for exotic pets and engage people in civic actions for wildlife conservation. Although messaging has been extensively used in conservation practice, little is known about how it can influence attitudes and various types of actions pertaining to the exotic pet trade. This study examined the impact of conservation messaging in the context of exotic pet ownership and wildlife entertainment visitation as common practices of the exotic pet trade. We randomly assigned participants in the United States to one of five messaging conditions: biodiversity loss and animal abuse (M1), zoonotic disease risks (M2), illegality (M3), social disapproval (M4), and neutral biological information as a control condition (M5). We found that all conservation messages (M1–M4) significantly decreased people's favorable attitudes toward the exotic pet trade and their desire to visit wildlife entertainment. However, conservation messaging did not influence the desire for exotic pet ownership or intentions to take civic actions. Our findings highlight the potential of conservation messaging for attitude change and demand reduction for wildlife entertainment, but different approaches are necessary for promoting more effortful actions such as exotic pet ownership and civic actions.
Experiences of stigma and subsequent reduced access to health care among women who inject drugs
Authors: Brener Loren , Cama Elena , Broady Timothy , Harrod Mary Ellen , Holly Carol , Caruana Theresa , Beadman Kim , Treloar Carla 
Published: January 2024

AbstractIntroductionResearch into stigma and injecting drug use has typically involved predominantly male participants, with limited research about the unique experience of women who inject drugs.MethodsThis study used survey methods to assess reduced access to health care due to stigma among a sample of women who inject drugs. Women (n = 232) completed a survey as part of a broader national study of people who inject drugs.ResultsOnly 46 (19.9%) women reported that they had not experienced any injecting drug use‐related stigma in the past year and most commonly noted ‘sometimes’ experiencing injecting‐related stigma (36.8%) with more than 75% of women reporting that health workers had treated them negatively because of their injecting drug use. Most women undertook strategies to prevent experiencing stigma, such as not disclosing drug use to a health worker (81.3%), not attending follow‐up appointments (76.7%) and delaying accessing health care (76.8%). Women with lower levels of personal wellbeing, who had experienced poorer treatment by health workers, had engaged in greater past month injecting, were employed and identified as lesbian, gay, bisexual, transgender or queer (LGBTQ) reported more reduced access to health care.Discussion and ConclusionsStigma has concerning health care implications for women who inject drugs and this research highlights the importance of understanding the impact of stigma in impeding health care access. Public health interventions should focus on addressing the systemic factors that reduce health care access for women who inject and take account of the impact of stigma in diminishing the quality and accessibility of health care for this group.
Severe tricuspid regurgitation with chordae tendinae rupture in CABG surgery
Authors: Li Xuejie , Hou Jianglong 
Published: January 2024

AbstractA 58‐year‐old male patient was admitted with chest pain and was diagnosed with coronary heart disease. He was scheduled for coronary artery bypass grafting (CABG) under cardiopulmonary bypass (CPB). Intraoperative real‐time transesophageal echocardiography (TEE) showed that the tricuspid valves were well‐aligned and subtle regurgitation. Real‐time TEE after separation from CPB showed severe tricuspid regurgitation and prolapsed chordae tendineae. The tricuspid chordae tendineae rupture due to a right atrial venous return cannula. The use of negative pressure to improve venous drainage during CPB may result in the tricuspid valve being adsorbed to the cannula, increasing the likelihood of injury to the tricuspid valve.
Prenatal features and postnatal follow‐up of congenital ventricular outpouching: A retrospective study of two centers in China
Authors: Fang Yanchun , Pan Yihong , Shen Liping , Luo Ting , Xu Weiming , Tao Shuangshuang , He Hailing , Zhao Bowen 
Published: January 2024

AbstractObjectivesCongenital ventricular outpouching (CVO) is a rare cardiac malformation that can manifest as congenital ventricular aneurysm (CVA) and/or congenital ventricular diverticula (CVD). In this study, we describe the prenatal features and postnatal follow‐up of 27 cases of CVO.MethodsThe clinical data of 27 patients with CVO who attended Sir Run Run Shaw Hospital Affiliated to the Medical College of Zhejiang University (Zhejiang Province, China) and Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University (Zhejiang Province, China) from April 2013 to October 2022 were retrospectively analyzed. The patients were also followed up by telephone. The prenatal characteristics and postnatal outcomes of the patients with CVO were evaluated.ResultsCVO was detected in 26 cases prenatally, 14 (51.85%) were diagnosed with CVA, nine (33.33%) were diagnosed with CVD, three (11.11%) were equivocal for CVA/CVD, and one (3.70%) was detected with CVA postnatally. Six patients underwent follow‐up fetal echocardiography approximately 4 weeks after the initial echocardiography examination, and a significant difference in CVO size was observed between the two examinations (P = .02). Eight patients (29.63%) demonstrated cardiovascular dysfunction, and the median CVO size in fetuses with and without cardiovascular dysfunction was 205 (range: 169–396) mm2 and 124 (range: 92–154.5) mm2, respectively (P = .01). Correlation was found between CVO size and fetal cardiac dysfunction (p = .000, r = .778). Eight patients (29.63%) had cardiac/extracardiac defects. Thirteen patients were live born, 12 were terminated pregnancies, and two were lost to follow‐up. The postpartum size of the CVOs remained stable in six patients, decreased in two patients, dissolved in three patients, and were surgically removed in two patients. With the exception of one patient with CVA complicated with complex congenital cardiac malformation who underwent surgical treatment after birth and who had postoperative left ventricular dysfunction (Case 1), the prognosis of all of the patients was good.ConclusionCVO is often associated with cardiac malformations. The size of prenatal CVOs can increase with gestational development, and cardiovascular dysfunction is significantly related to CVO size. The postpartum prognosis of patients with CVO is good. Echocardiography plays a key role in the diagnosis of congenital ventricular outpouching. Prenatal counseling should be cautious regarding the diagnosis and the prognosis although our cases had a favorable prognosis.
Clinical significance of aortic spontaneous echo contrast in patients with nonvalvular atrial fibrillation
Authors: Hasegawa Hitomi , Ito Takahide , Akamatsu Kanako , Hoshiga Masaaki 
Published: January 2024

AbstractBackgroundLittle is known about spontaneous echo contrast (SEC) in the descending aorta (DASEC), occurring with or without SEC in the left atrium (LASEC), in the presence of atrial fibrillation (AF). We examined the clinical significance of DASEC, including its relationship with LASEC, in patients with nonvalvular AF.MethodsAmong 176 patients, 41 (23%) had DASEC and 51 (29%) had LASEC. The patients were divided into four groups based on the presence/absence of LASEC and DASEC, as Group A: no SEC (n = 107); Group B: only LASEC (n = 28); Group C: only DASEC (n = 18); and Group D: both types of SEC (n = 23). Clinical and echocardiographic parameters were compared between groups, and the possible determinants of DASEC were evaluated.ResultsAge, sex, and CHA2DS2‐VASc score were similar in the four groups. Group D was more likely to have an increased LA diameter, decreased left ventricular ejection fraction (LVEF), and low LA appendage velocity compared to Group A. Group C had a smaller LA diameter and a higher appendage velocity than Group B. Multivariate logistic regression analysis, with age ≥75 years, female sex, LASEC, LVEF < 50%, and presence of DA plaques included as covariates, showed that LASEC (OR 4.22, 95% CI 1.92–9.26, p < .001) and LVEF < 50% (OR 2.70, 95% CI 1.12–6.52, p = .027) were significant determinants of DASEC. The prevalence of DASEC increased with increasing LASEC severity in order of none (13%), mild (28%), and dense (50%) (p < .001).ConclusionsIn nonvalvular AF patients, DASEC is common, and it partly originates from LASEC, particularly in the presence of LV systolic dysfunction.
Using OpenAI GPT to Generate Reading Comprehension Items
Authors: Sayin Ayfer , Gierl Mark 
Published: January 2024

AbstractThe purpose of this study is to introduce and evaluate a method for generating reading comprehension items using template‐based automatic item generation. To begin, we describe a new model for generating reading comprehension items called the text analysis cognitive model assessing inferential skills across different reading passages. Next, the text analysis cognitive model is used to generate reading comprehension items where examinees are required to read a passage and identify the irrelevant sentence. The sentences for the generated passages were created using OpenAI GPT‐3.5. Finally, the quality of the generated items was evaluated. The generated items were reviewed by three subject‐matter experts. The generated items were also administered to a sample of 1,607 Grade‐8 students. The correct options for the generated items produced a similar level of difficulty and yielded strong discrimination power while the incorrect options served as effective distractors. Implications of augmented intelligence for item development are discussed.
Knowledge Integration in Science Learning: Tracking Students' Knowledge Development and Skill Acquisition with Cognitive Diagnosis Models
Authors: Xu Xin , Ren Shixiu , Zhang Danhui , Xin Tao 
Published: January 2024

AbstractIn scientific literacy, knowledge integration (KI) is a scaffolding‐based theory to assist students' scientific inquiry learning. To drive students to be self‐directed, many courses have been developed based on KI framework. However, few efforts have been made to evaluate the outcome of students' learning under KI instruction. Moreover, finer‐grained information has been pursued to better understand students' learning and how it progresses over time. In this article, a normative procedure of building and choosing cognitive diagnosis models (CDMs) and attribute hierarchies was formulated under KI theory. We examined the utility of CDMs for evaluating students' knowledge status in KI learning. The results of the data analysis confirmed an intuitive assumption of the hierarchical structure of KI components. Furthermore, analysis of pre‐ and posttests using a higher‐order, hidden Markov model tracked students' skill acquisition while integrating knowledge. Results showed that students make significant progress after using the web‐based inquiry science environment (WISE) platform.