bluuebunny/crossref_metadata_2025_split huggingface dataset:
Breaking Through the Luminescence Stability Bottleneck of Oxyfluoride Phosphor for Sun‐Like Led Lighting
Authors: Li Ying , Fang Shuangqiang , Zhu Qiangqiang , Li Shuxing , Liu Bo , Feng Fu , Xie Rongjun , Wang Le 
Published: January 2024

AbstractSunlight like optical source is the primary objective of healthy lighting. In contrast, achieving full spectrum lighting with high stability remains challenging, mostly due to the scarcity of purple chip‐pumped cyan‐green phosphors and their inherent emission instability. In this study, a novel strategy is presented that realizes simultaneous enhancements in both humidity stability (increased by 2.9 times) and luminescence quantum efficiency (enhanced by 1.5 times) for cyan‐emitting Sr3AlO4F:Ce3+ phosphor by employing Si/N doping. Theoretical modelling shows that these improvements are attributed to the regulation of energy bands and structural rigidity as well as modulation of the ionicity of chemical bonds. Furthermore, blending the other violet chip‐pumped phosphors, sun‐like LEDs that accurately replicate solar spectra in different times of the day with an optimal color rendering index of 99 is successfully engineered. Moreover, the universality of this strategy on other oxyfluoride phosphors has also been validated. This groundbreaking outcome offers a practical solution to overcome the inherent luminescence stability limitations in oxyfluoride phosphors, thus catalyzing the application of these cyan‐green candidates in sun‐like LED lighting.
3D‐Printed Inherently Antibacterial Contact Lens‐Like Patches Carrying Antimicrobial Peptide Payload for Treating Bacterial Keratitis
Authors: Ch Sanjay , Mishra Priyasha , Padaga Sri Ganga , Ghosh Balaram , Roy Sanhita , Biswas Swati 
Published: January 2024

AbstractDelivery of therapeutic agents through contact lenses‐like patches is a promising strategy to achieve significant bioavailability with negligible eye drainage. The present study investigates the preparation and 3D printing of mucoadhesive gelatin methacryloyl (GelMA)/chitosan methacryloyl (ChiMA) hydrogels to fabricate them as contact lens‐like patches (CLP) loaded with antimicrobial peptide, S100A12 (AMP) for treating bacterial keratitis (BK). Extrusion technology is used to print the patches layer by layer to form a hemispherical scaffold suitable for eyewear, and 3D‐printed CLP is crosslinked using Irgacure 2959 under UV light. The results from the in vivo experiment conducted on Pseudomonas aeruginosa‐infected BK rabbit model after the treatment with AMP‐loaded CLP have shown a significant decrease in bacterial load when plated for CFU. The newly developed delivery system containing AMP has great potential to overcome the treatment challenges of multidrug resistance (MDR) in bacteria and eliminate the frequent dosing associated with eye drops. The presence of chitosan in the formulation provides a synergetic effect on the AMP in disrupting bacterial biofilms. The ease of using 3D printing will open new avenues for optimizing the dosage depending on the severity of the BK in the patients, which can be used as personalized medicine.
13C NMR as an analytical tool for the detection of carbonic acid and pKa determination
Authors: Oliveira Daniel Rossado , da Costa Eric Tavares , Schenberg Leonardo Araujo , Ducati Lucas Colucci , do Lago Claudimir Lucio 
Published: January 2024

AbstractNMR spectroscopy has become a standard technique in studies both on carbon capture and storage. 13C NMR allows the detection of two peaks for carbonated aqueous samples: one for CO2(aq) and another one for the species H2CO3, HCO3−, and CO32−—herein collectively named HxCO3x‐2. The chemical shift of this second peak depends on the molar fraction of the three species in equilibrium and has been used to assess the equilibrium between HCO3− and CO32−. The detection of H2CO3 at low pH solutions is hindered, because of the concurrent liberation of CO2 when the medium is acidified. Herein, a valved NMR tube facilitates the detection of the HxCO3x‐2 peak across a wide pH range, even at pH 1.8 where the dominant species is H2CO3. The method employed the formation of frozen layers of NaH13CO3 and acid solutions within the tube, which are mixed as the tube reaches room temperature. At this point, the tube is already securely sealed, preventing any loss of CO2 to the atmosphere. A spectrophotometry approach allowed the measurement of the actual pH inside the pressurized NMR tube. The chemical shift for H2CO3 was determined as 160.33 ± 0.03 ppm, which is in good agreement with value obtained by DFT calculations combined with Car–Parrinello molecular dynamics. The H2CO3 pKa value determined by the present method was 3.41 ± 0.03, for 15% D2O aqueous medium and 0.8 mol/L ionic strength. The proposed method can be extended to studies about analogs such as alkyl carbonic and carbamic acids.
Sleep and fatigue management strategies: How nurses, midwives and paramedics cope with their shift work schedules—a qualitative study
Authors: Booker Lauren A. , Fitzgerald Jarrah , Mills Jane , Bish Melanie , Spong Jo , Deacon‐Crouch Melissa , Skinner Timothy C. 
Published: January 2024

AbstractAimsTo understand the benefits and challenges of shift work, and the coping strategies used by nurses, midwives and paramedics to manage the impact of shift work on sleep and fatigue from shift work.DesignA single case study with embedded units.MethodsTwenty‐seven participants were interviewed exploring their shift work experiences, coping strategies used to improve sleep, and what their recommendations are for improving shift work management. Interviews were completed between November and December 2022.ResultsParticipants enjoyed the lifestyle, flexibility and financial rewards offered by working shift work. However, fatigue and sleep deprivation undermined these benefits, as it impacted their ability to enjoy social and family events. There were also concerns of long‐term health consequences of shift work and delivery of care. Changes to rostering practices and sleep and shift work education were common recommendations.ConclusionThis study provides insights on how healthcare professionals manage sleep and fatigue due to shift work and the inadequate support. There is absence of adequate policies, processes and training at an organizational, academic and personal level on how to best manage sleep and fatigue when working shift work. Future research is needed to explore how to equip healthcare shift workers with the skills to successfully manage their schedules to mitigate the negative impact that poor sleep and fatigue has on the health and safety of themselves and their patients.Implications for the Profession and/or Patient CareUnderstanding the specific challenges of shift work and how workers manage their shift work schedules is critical for improving the health and safety of themselves and their patients. This study identified that there is insufficient training regarding sleep and shift work management strategies, potentially leading to occupational health and safety concerns. Further education and training to equip staff with the necessary information, training and guidance to staff on how to reduce fatigue risk is required.Patient or Public ContributionThis study involved healthcare shift workers in semi‐structured interviews. Data gathered from a previous survey that participants were involved in helped shape the interview topics and the study design.
A multicenter, single‐arm, open‐label interventional study of adherence to brexpiprazole during switching from previous antipsychotic drugs in patients with schizophrenia or schizoaffective disorder
Authors: Nakagome Kazuyuki , Tachimori Hisateru , Endo Shiro , Murakami Ken , Azekawa Takaharu , Hongo Seiji , Niidome Kazunari , Kojima Yoshitsugu , Yamada Sakiko , Oi Hideki , Sumiyoshi Tomiki 
Published: January 2024

AbstractThe rate of medication persistence was examined in patients with schizophrenia or schizoaffective disorder during switching from previously administered antipsychotics to brexpiprazole, a new dopamine D2 receptor partial agonist. A multicenter, single‐arm, open‐label 24‐week interventional study was conducted, consisting of two 12‐week consecutive periods: an initial switch (by plateau cross‐titration) with the subsequent period, followed by a second maintenance period. Prior antipsychotics were olanzapine or risperidone/paliperidone. The primary and secondary outcome measures were medication persistence rates after the first 12 weeks and changes from baseline in the Specific Levels of Functioning Scale (SLOF), Subjective Well‐being under Neuroleptic drug treatment Short form (SWNS), and Positive and Negative Syndrome Scale (PANSS) scores, respectively. In total, 79 patients were administered brexpiprazole and the medication persistence rate at 12 weeks was 78.5%, which was significantly higher than the predefined threshold of 65%. Regarding the prior medication, the persistence rate at 12 weeks was 84.6% for olanzapine and 72.5% for risperidone/paliperidone. Significant improvements from baseline were observed in the SLOF, SWNS, and PANSS scores. There were no adverse events of concern. Thus, brexpiprazole appeared to be a suitable antipsychotic on switching from olanzapine, risperidone, or paliperidone.
A ketogenic diet lowers myocardial fatty acid oxidation but does not affect oxygen consumption: a study in overweight humans
Authors: Luong Thien Vinh , Pedersen Mette Glavind Bülow , Abild Caroline Bruun , Cunnane Stephen C. , Croteau Etienne , Lauritsen Katrine Meyer , Kjærulff Mette Louise Gram , Tolbod Lars Poulsen , Møller Niels , Søndergaard Esben , Gormsen Lars Christian 
Published: January 2024

AbstractObjectiveA ketogenic diet (KD) characterized by very low carbohydrate intake and high fat consumption may simultaneously induce weight loss and be cardioprotective. The “thrifty substrate hypothesis” posits that ketone bodies are more energy efficient compared with other cardiac oxidative substrates such as fatty acids. This work aimed to study whether a KD with presumed increased myocardial ketone body utilization reduces cardiac fatty acid uptake and oxidation, resulting in decreased myocardial oxygen consumption (MVO2).MethodsThis randomized controlled crossover trial examined 11 individuals with overweight or obesity on two occasions: (1) after a KD and (2) after a standard diet. Myocardial free fatty acid (FFA) oxidation, uptake, and esterification rate were measured using dynamic [11C]palmitate positron emission tomography (PET)/computed tomography, whereas MVO2 and myocardial external efficiency (MEE) were measured using dynamic [11C]acetate PET.ResultsThe KD increased plasma β‐hydroxybutyrate, reduced myocardial FFA oxidation (p < 0.01) and uptake (p = 0.03), and increased FFA esterification (p = 0.03). No changes were observed in MVO2 (p = 0.2) or MEE (p = 0.87).ConclusionsA KD significantly reduced myocardial FFA uptake and oxidation, presumably by increasing ketone body oxidation. However, this change in cardiac substrate utilization did not improve MVO2, speaking against the thrifty substrate hypothesis.image
Electron beam radiation constructed and improved bone repairing performance based on hierarchical thermoplastic polyurethane/graphene oxide/hydroxyapatite hot melt adhesive with high flow ductility
Authors: Yang Jinyu , Liu Kun , Wang Zhijun , Rao Lu , Fu Lili , Tang Dongxu , Yang Xiaojie , Li Yuesheng , Chen Huangqin , Liu Yi 
Published: January 2024

AbstractThe aging population increased the demand for the development and utilization of bone filling materials. In this study, hydroxyapatite (HAP) and graphene oxide (GO) were introduced into thermoplastic polyurethane (TPU) by melt mixing and electron beam radiation to obtain the new hot melt adhesive (TPU/HAP/GO). The structures and morphologies of the TPU/HAP/GO were analyzed using FTIR, XRD, SEM, BET, DSC. The mechanical properties of the TPU/HAP/GO were evaluated using a universal testing machine. TPU/HAP/GO was demonstrated to have good bacterial inhibition by the zone of inhibition test and plate method. The good biocompatibility of the hot melt adhesive was demonstrated using the MTT method and the Hoechst 33342/PI double staining method. The osteogenic differentiation of mouse osteoblasts (MC3T3‐E1) treated with TPU/HAP/GO was detected by alkaline phosphatase (ALP) staining. ALP staining showed that the hot melt adhesive promoted the differentiation of MC3T3‐E1 cells into osteoblasts. This hot melt adhesive had great application potential in bone tissue engineering.Highlights
Green electron beam radiation method for synthesizing hot melt adhesives.
Enhanced mechanical properties of composites by incorporation of graphene oxide.
Improvement of antimicrobial and osteogenic capacities for polyurethane.
Multiscale simulation of hygrothermal stress and mechanical properties degradation of carbon fiber reinforced polymers laminates
Authors: Yu Haiyan , Ze Gao , Zhang Daixin , Xing Ping 
Published: January 2024

AbstractA mesoscopic representative volume element (RVE) model of carbon fiber reinforced polymers (CFRP) laminate with 15 plies was established based on the principle of fiber random disturbance. The RVE model was validated by comparing the elastic parameters calculated by the RVE model, Chamis model, and Bridge model. Wet stress and thermal stress were coupled using a sequential method. Macroscopic and microscopic subroutines were developed to calculate the stress–strain field of CFRP laminate and RVE model. A multiscale numerical simulation of three‐point bending of moisture‐saturated CFRP laminate was conducted. Failure process and failure modes of CFRP laminate were discussed based on the multiscale simulation and SEM observations. The results show that the RVE model and the multiscale simulation strategy presented in this work can predict the coupled hygrothermal stress and the strength degradation due to moisture absorption very well. The maximum error between the simulated and experimental averaged force of the moisture‐saturated CFRP laminate subjected to three‐point bending is about 3.4%. Multiscale simulation demonstrated that uneven distribution of fibers can result in the fiber/matrix interfaces bearing a larger transverse stress in the fiber's dense distribution area. It is the main reason that results in fiber/matrix interface failure of CFRP laminates working in hygrothermal environments.Highlights
A RVE model of CFRP laminate was presented using fibers random disturbance.
Coupled hygrothermal stress of single fiber and surrounded matrix was obtained.
A multiscale simulation of the strength change of the CFRP plate due to wet‐thermal stress was conducted.
Failure modes of CFRP laminate are discussed based on the multiscale simulation.
Void stability process window and parametric optimization for filament‐wound composite riser
Authors: Kang Chao , Zhan Jun , Ye Shuang , Liu Zan , Guo Jian , Deng Bo , Chen Zhen 
Published: January 2024

AbstractThe manufacturing process parameters play a critical role in determining the quality of resin‐matrix composite structures. This study aims to investigate the impact of process parameters on void content and identify the stable and minimal void content of nano‐reinforced filament‐wound risers. Fourteen process parameters were initially designed, taking into account winding tension, speed, and curing time, based on the Box–Behnken design method. Subsequently, a void content model was developed using the response surface method, utilizing experimental data. The study further explores the effects of individual and combined process parameters on void content and establishes a stable process window through sensitivity analysis. Finally, the PSO‐GWO algorithm is employed to optimize winding tension, speed, and curing time with the objective of reducing void content. The results of the numerical analysis highlight the significant influence of curing time on void content, and the optimal parametric combination is determined to be 48.4 N winding tension, 12.6 m/min winding speed, and 6.7 h of curing time.Highlights
Winding tension and rate have a similar impact on porosity content.
Void content sensitivity to tension is affected by feed rate and curing time.
The stable process windows are winding tension [28 N, 53 N], feed rate [30%, 78%], and curing time [5.1 h, 8.4 h].
The optimal parameters combination is 48.4 N, 63%, and 6.7 h.
Bio‐guided isolation of aromatic abietane diterpenoids from Salvia canariensis as biopesticides in the control of phytopathogenic fungi
Authors: López‐Cabeza Rocío , Rodríguez‐Sabina Samuel , Reyes Carolina P , Expósito Daniela G , Giménez Cristina , Jiménez Ignacio A , Cabrera Raimundo , Bazzocchi Isabel L 
Published: January 2024

AbstractBackgroundBiofungicides arise as a promising alternative to the indiscriminate use of harmful synthetic fungicides in crop management.ResultsThe present study reports the bio‐guided fractionation of an endemic plant from the Canary Islands, Salvia canariensis against the phytopathogens, Alternaria alternata, Botrytis cinerea, and Fusarium oxysporum. This procedure allowed identifying a series of diterpenoids with an abietane skeleton (1–5), which exhibited remarkable activity against the phytopathogenic fungi assayed. Their structures were established by means of spectroscopic and spectrometric methods, as well as comparison with reported data. Compounds 2 (carnosic acid), 4 (11‐acetoxy carnosic acid) and 5 (11,12‐diacetoxy carnosic acid) showed significant mycelium growth inhibition (%GI > 50 at 0.1 mg/mL concentration) on all the assayed fungi, and with a potency also higher than the positive control, Fosbel‐Plus, a fungicide commonly used in agriculture. A preliminary structure–activity relationship is also discussed.ConclusionsThese findings underline the aromatic abietane diterpenoids as promising eco‐friendly alternatives to conventional fungicides to use in integrated pest management. © 2024 The Authors. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
Biochar/α‐Fe2O3/γ‐Fe2O3 Heterjunction Composite for Photocatalytic Removal of Amino Black
Authors: Chen Feng , Chen Xiao , Li Peihe , Zhang Jingwen , Li Wanfei , Wang Gelan , Zhou Haoyu , Xie Youfeng , Chen Zhigang , Liu Chengbao 
Published: January 2024

AbstractHerein we synthesized biochar/iron oxide composite (C/α‐Fe2O3/γ‐Fe2O3) by two‐step calcination method. The prepared C/α‐Fe2O3/γ‐Fe2O3 had a highly pure and a concentration ratio of α‐Fe2O3 and γ‐Fe2O3 about 1 : 1. The optical properties of as‐synthesized C/α‐Fe2O3/γ‐Fe2O3 show a lower bandgap energy (1.90 eV) than that of pure C/α‐Fe2O3 (2.02 eV). The effects of different biochar composite catalysts on the removal of amino black were investigated. Upon illumination, the total removal rate of amino black dye by C/α‐Fe2O3/γ‐Fe2O3 catalyst reached 98 %, which was about 1.7 times that of C/α‐Fe2O3. In addition, the coercivity and the remanence intensity of C/α‐Fe2O3/γ‐Fe2O3 is respectively 1.81 times and 7.17 times that of C/α‐Fe2O3. The catalyst could be magnetically separated and reused for five times with a slight loss of its reactivity. The study of biochar composite provides a new direction for the removal of toxic organic dye in wastewater.
Nickel Hydroxides: Requirements, Targeted Construction and Choice of Characteristics and Industrially Applicable Synthesis for Targeted Use in Electrochemical Devices
Authors: Kovalenko Vadym , Kotok Valerii 
Published: January 2024

AbstractNickel hydroxides (monohydroxides of several modifications and layered double hydroxides, based on nickel hydroxide) have high electrochemical, electrochromic, and electrocatalytic properties that allow them to be effectively used as an active substance in alkaline batteries, hybrid supercapacitors, electrochemical sensors, for electrocatalytic oxidation of organic substances and as an electrochromic device. Each application has its specific requirements for nickel hydroxides which must be defined. For an effective application, it is necessary to carry out a targeted construction of structure and composition, and selection of characteristics of nickel hydroxides and to develop targeted methods and conditions for nickel hydroxide synthesis. The structure, properties, and methods of preparation for use in various fields of nickel hydroxide application have been considered from the targeted ternary points of view: requirements definition, types and characteristics selection, and applying the synthesis method in industry. The 3‐level hierarchical complex of mechanisms for the formation of nickel hydroxides has been described. Also, the contribution of Ukrainian scientists to research in the field of nickel hydroxides is considered.
Pyrene‐Appended Luminescent Probes for Selective Detection of Toxic Heavy Metals and Live Cell Applications
Authors: Srivastava Ankur , Mishra Gargi , Pathak Amit Kumar , Pandey Saurabh , Awasthi Chhama , Pandey Mrituanjay D. , Behera Kamalakanta 
Published: January 2024

AbstractHeavy metal contamination has become a global environmental problem and currently drawn much attention from researchers in worldwide. High exposure to heavy metals can lead to problems like kidney, liver and brain damage, skin and lung cancer, etc. Rapid and sensitive detection of heavy metals is of immense importance in environmental monitoring. Over the past few decades, enormous efforts have been made to design various sensors to identify and monitor these harmful metal ions. In Comparison with other methods, fluorescence‐based chemosensors have received extensive attention because of the advantages of high sensitivity, low cost, real‐time monitoring, simple operation, etc. The pyrene derivatives are significant polycyclic aromatic hydrocarbons (PAHs) with strong fluorescence. They are widely used as fluorescent probes in many applications due to their easy modification, high fluorescence quantum yield, and strong fluorescence emission in live cells, outstanding cell permeability, and very low cytotoxicity. The SDG 6: Clean water and sanitation alarm a strong strategy, and careful identification of the risk connected to environmental pollutants needs urgent attention in this situation. Therefore, we highlight different types of pyrene‐based fluorophores and the fluorescence mechanisms for the sensitive and selective detection methodology of Arsenic, Mercury, Cadmium, Lead, and Chromium heavy metals.
Ligand and Strain Synergistic Effect in NiFeP0.32 LDH for Triggering Efficient Oxygen Evolution Reaction
Authors: Chen Hao , Ma Yongbing , Han Yun , Mao Xin , Hu Yongbin , Zhao Xin , Dong Qinglong , Wen Bo , Du Aijun , Wang Xin , Lyu Xiao , Jia Yi 
Published: January 2024

AbstractDeveloping efficient water‐splitting electrocatalysts to accelerate the slow oxygen evolution reaction (OER) kinetics is urgently desired for hydrogen production. Herein, ultralow phosphorus (P)‐doped NiFe LDH (NiFePx LDH) with mild compressive strain is synthesized as an efficient OER electrocatalyst. Remarkably, NiFePx LDH with the phosphorus mass ratio of 0.32 wt.% and compressive strain ratio of 2.53% (denoted as NiFeP0.32 LDH) exhibits extraordinary OER activity with an overpotential as low as 210 mV, which is superior to that of commercial IrO2 and other reported P‐based OER electrocatalysts. Both experimental performance and density function theory (DFT) calculation demonstrate that the doping of P atoms can generate covalent Fe─P coordination bonds and lattice distortion, thus resulting in the consequent depletion of electrons around the Fe active center and the downward shift of the d‐band center, which can lead to a weaker adsorption ability of *O intermediate to improve the catalytic performance of NiFeP0.32 LDH for OER. This work provides novel insights into the distinctive coordinated configuration of P in NiFePx LDH, which can result in superior catalytic performance for OER.