bluuebunny/crossref_metadata_2025_split huggingface dataset:
Inmediatez en salud: la tecnología RSS
Authors: Michán-Aguirre Layla , Romero-Pérez Minerva Minerva 
Published: January 2024

Actualmente estamos en la era digital, donde el formato virtual y las tecnologías computacionales han brindado un gran avance en la investigación de las ciencias biológicas. El uso de la información es más sencillo y eficiente si se sigue un proceso adecuado y se aplican los recursos pertinentes para cada función, por esto existen una gran cantidad de herramientas para generarla, procesarla, compartirla y analizarla, por ejemplo, el Really Simple Syndication (RSS por sus siglas) o también llamada la sindicación realmente simple, se refiere a una familia de formatos de ‘alimentación web’. Ayuda a conectar a los usuarios con aquellas fuentes que son de su interés para mantenerlos actualizados por medio de un monitoreo inteligente y les simplifica enormemente la tarea de encontrar información útil. El usuario recibe notificaciones en un solo lugar cada vez que se produce una actualización, sin necesidad de consultar distintas fuentes como sitios web, canales de videos, cuentas de redes sociales, revistas y noticias.
A diferencia de los otros canales de comunicación, como el correo electrónico o las redes sociales, la sindicación simple tiene un solo sentido, que inicia con las fuentes a las que el usuario se ha suscrito y termina cuando el usuario recibe las actualizaciones en un lector de RSS, el proceso no implica ninguna otra interacción, es una comunicación directa formada por unidades de información simples y útiles. La sindicación de contenido web a través de formatos estándar como el RSS se ha convertido en un mecanismo cada vez más popular para difundir y recibir nueva información en salud, por ejemplo, el tema del COVID-19, que ha sido de importancia en los últimos años. Esta es una de las tecnologías minimalistas, sin publicidad, directas y abiertas que les invitamos a utilizar, implementar y compartir.
DETERMINATION OF TOTAL PHENOLIC AND FLAVONOID CONTENT AND EVALUATION OF ANTIOXIDANT ACTIVITIES OF CUSCUTA REFLEXA
Authors: Azad Abul Kalam , Mohamed Farahidah 
Published: January 2024

Background: The aim of the study was to identify functional groups and antioxidant activity of the Cuscuta reflexa (C. reflexa) stems extract. Due to the reach of medicinal components, it has been using among Indian subcontinent people to treat various chronic diseases for ancient era. However, there are lacks of study on antioxidant activities of C. reflexa with its potential therapeutic compounds, therefore this study motivated to investigate more on its stems extract for further explore.
Methods: Soxhlet extraction method was employed to extract phenolic compounds from C. reflexa stems. The effect of extraction time (1-4 h) and concentration of ethanol (45%, 60%, 75% and 90%) on the percentage of yield, total phenolic (TPC) and flavonoid content (TFC) was investigated. The functional groups of phenolic compounds were characterized by using Fourier Transform Infrared Spectrometry (FTIR). DPPH and ABTS•+ radical scavengers were used to evaluate antioxidant activity.
Results: Data showed the highest percentage of yield (10.22±0.14% w/w), TPC (64.11±0.17%, mg GAE/g d.w.) and TFC (41.08±0.34%, mg QE/g d.w.) at 3 h with 75% ethanol. FTIR results revealed the presence of functional groups associated phenolic compounds which are the band at 1260 cm−1 illustrations the C–O groups of polyols existence and C – O –C of ester for presence of quercetin which represent the hydroxy flavonoids in the extract. DPPH and ABTS•+ radical scavengers were showed very potent antioxidant activity with IC50 295.12±1.33 and 245.43±0.78 μg/mL.
Conclusion: Phenolic and flavonoids enriched C. reflexa extract may play a potential role as a natural nutritional and therapeutic source in Bangladesh.

Peer Review History:
Received: 27 October 2023; Revised: 19 November; Accepted: 28 December, Available online: 15 January 2024
Academic Editor: Dr. Ali Abdullah Al-yahawi, Al-Razi university, Department of Pharmacy, Yemen, alyahawipharm@yahoo.com
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewers:
Dr. Sangeetha Arullappan, Universiti Tunku Abdul Rahman, Malaysia, sangeetha@utar.edu.my
Prof. Ali Gamal Ahmed Al-kaf, Sana'a university, Yemen, alialkaf21@gmail.com
ACUTE TOXICITY AND HEPATO-RENAL PROTECTION OF LIME JUICE, HONEY AND THEIR FLAVONOID-RICH FRACTIONS IN HIGH FAT-DIET INDUCED OBESE RAT MODEL
Authors: Alexander Idoko , Elijah Parker Joshua , Uzoma Njoku Obioma , Ifeanyi Ejike David , Victor Egbuji Jude , Patrick O Ugwudike , Chioma Jennifer Ndubuisi 
Published: January 2024

Introduction: A major consideration for the use of alternative herbal medicine from natural compounds is the concern of safety due to possible toxicity. This study evaluated the safety and hepato-renal protection of fresh lime juice (FLJ), raw honey (RH) and their flavonoid-rich fractions in obese rat induced high fat-diet (HFD).
Methods: Oral acute toxicity (LD50) study involved 24 female Wistar rats, divided into 8 groups of 3 rats, administered 300 mg/kg and 2000 mg/kg of FLJ, RH, methanol flavonoid rich fraction of lime juice (MFLJ) and ethyl acetate flavonoid rich fraction of honey (EAFH) respectively, for 14 days. Simultaneously, for the anti-obesity study, 24 neonate Wistar rats of 21-days old, divided into 2 groups of 12 rats (for obesity induction phase-1, for two weeks), and regrouped into 4 groups of 4 rats (14 days treatment phase-2), were used.
Results: Result of LD50 on FLJ, RH, MFLJ, and EAFH showed no toxicity, no motility, and body weight of rats was not adversely affected evenup to 2000 mg/kg.The increased body weight of the HFD-obese rats was significantly (p<0.05)reduced compared to control. There was significant (p<0.05) decrease in activities of aspartate aminotransferase and alanine aminotransferase after MIX, MFLJ and EAFH administration, compared with control. Also, total protein and bilirubin concentrations was not significantly (p<0.05) different compared to control. Administration of EAFH significantly (p<0.05) reduced the concentrations of creatinine, urea, potassium, and chloride; while MIX and EAFH significantly (p<0.05) increased their concentrations compared to control.
Conclusion: It may be concluded that FLJ, RH, MFLJ, and EAFH are safe for consumption and also possess liver and renal protection.

Peer Review History:
Received: 27 October 2023; Revised: 19 November; Accepted: 28 December, Available online: 15 January 2024
Academic Editor: Dr. Asia Selman Abdullah, Pharmacy institute, University of Basrah, Iraq, asia_abdullah65@yahoo.com
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 7.5/10
Reviewers:
Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id
Dr. Sangeetha Arullappan, Universiti Tunku Abdul Rahman, Malaysia, sangeetha@utar.edu.my
Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622, Giza, Egypt, gehankandeel9@yahoo.com
TOXICITY PROFILING OF THE CO-ADMINISTRATION OF THE ESSENTIAL OIL OF PIPER GUINEENSE AND QUININE IN RATS
Authors: DANIYAN Michael Oluwatoyin , OGUNYEMI Temitope Helen , OLAWUNI Idowu Julius , ASIYANBOLA Isaac Damilare , ADELODUN Stephen Taiye , OPOGGEN Tivere Susan , OYEMITAN Idris Ajayi 
Published: January 2024

Background: The co-administration of medicinal plant products with orthodox drugs is not uncommon with a view to enhancing efficacy and improving treatment outcomes. However, reports indicated that such combinations may also enhance associated toxic effects. We recently reported that though the co-administration of essential oil of P. guineense (EOPG) and Quinine has the potential to improve treatment outcomes in experimental cerebral malaria, the observed deaths associated with higher co-administered doses necessitated the need for further toxicological evaluation.
Method: Rats were randomly divided into 12 groups (n=10), consisting of control, quinine, EOPG (12.5, 25, 50, 100, and 150 mg/kg), and their respective Quinine combinations. Control received vehicle (5% Tween 80 in distilled water), Quinine was given at a dose of 20 mg/kg stat, then 10 mg/kg twice daily for the next two days, while other groups were treated once daily for 3 days. All doses were administered intraperitoneally and rats were assessed for weights and novelty-induced behaviors (NIB). On day 4, rats were randomly sub-grouped into Treated and non-dosing Recovery (n=5) and sacrificed on day 4 and 18 respectively. Blood and organ samples were processed for hematological, biochemical, and histopathological evaluation.
Results: In this study, analysis of our results showed that co-administration of EOPG and Quinine revealed significant alterations in body and organ weights, rearing, grooming, and locomotion, as well as biochemical and hematological, and liver histoarchitecture, with potential for persistent toxicity.
Conclusion: We propose that the earlier reported death associated with the co-administration of EOPG with Quinine in experimental cerebral malaria may be associated with increased toxicity on the liver and risk of heart-related diseases. This study concludes that despite the beneficial effects of EOPG/Quinine co-administration at lower doses, caution is advised.

Peer Review History:
Received: 20 October 2023; Revised: 15 November; Accepted: 29 December, Available online: 15 January 2024
Academic Editor: Prof. Dr. Gorkem Dulger, Duzce University, Turkey, gorkemdulger@yandex.com
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 7.5/10
Reviewers:
Dr. Gehan Fawzy Abdel Raoof Kandeel, Pharmacognosy Department, National Research Centre, Dokki, 12622, Giza, Egypt, gehankandeel9@yahoo.com
Ahmad Najib, Universitas Muslim Indonesia, Makassar, Indonesia, ahmad.najib@umi.ac.id
OUTCOME OF AZITHROMYCIN AND MONOSODIUM GLUTAMATE ON HISTOLOGIC AND BIOCHEMICAL ALTERATIONS IN RATS’ LIVER
Authors: Egbuonu Anthony Cemaluk Chinedum , Alaebo Prince Ogochukwu , Eze Obioma Benedeth , Achi Ngozi Kalu , Njoku Chinomso Juliet 
Published: January 2024

Background: Monosodium glutamate (MSG), a commonly used flavouring, mediated hepatotoxic and pro-inflammatory responses. Azithromycin (AZT), an antibiotic with anti-inflammatory activity, may be co-consumed with MSG to present unknown outcomes on the liver, a major organ for the detoxification of xenobiotics.
Aim: This study evaluated the effect of AZT and MSG on histologic and biochemical changes in rats’ liver.
Methods: Thirty rats in five groups were for seven successive days orally exposed to groups 1, (distilled water 1 mL Kg−1), 2, (MSG 8000 mg/kg), 3, overdose AZT, OAZT (AZT 412.5 mg Kg−1), 4, therapeutic concentration AZT, TAZT, (AZT 82.5mg Kg−1), and 5, (TAZT 82.5 mg Kg−1 + MSG 8000 mg Kg−1). Liver function markers in therats’ serum and liver tissue, and changes in the liver histologic were assessed by acceptable protocols. The mean of numeric data were tested for significance at p value less than 0.05 by analysis of variance (ANOVA).
Results: MSG treatment significantly (p<0.05) increased hepatic and serum alanine aminotransferase activity (ALT), aspartate aminotransferase activity (AST), alkaline phosphatase activity (ALP), total bilirubin concentration (T-BIL), and direct bilirubin concentration (D-BIL) but decreased albumin concentration (ALB) compared to control and others. TAZT treatment caused a significant (p<0.05) decrease in these effects unlike MSG and OATZ treatments while TAZT + MSG co-treatment significantly (p<0.05) reversed these effects compared to MSG-treated rats. Rats’ liver sections for rats in groups 2 and 3 showed severe hepatocellular degeneration and necrosis compared to others while those in group 4 (TAZT) showed the normal hepatic histo-architecture comparable to those in group 1 (control). Those in group 5 showed marked cellular swelling and leukocytic infiltration in only the centrilobular areas, suggesting active restorative responses.
Conclusion: Thus, TAZT significantly mitigated the compromised histologic and biochemical integrities of liver function due to MSG treatment in rats via probable normalization of their enzymatic and non-enzymatic indicators of liver function. This suggests that TAZT could be useful in managing histologic and biochemical malfunction of rats’ liver due to MSG assault.

Peer Review History:
Received: 12 October 2023; Revised: 9 November; Accepted: 13 December, Available online: 15 January 2024
Academic Editor: Dr. Marwa A. A. Fayed, University of Sadat City, Egypt, maafayed@gmail.com
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewers:
Idoko Alexander, Caritas University, Enugu, Nigeria, idokoalexander1@gmail.com
Dr. Dennis Amaechi, MrsFoluBabade Mini Estate, Flat 5 by Old Soldiers Quarter, Sabongari/Bwari, Abuja- Federal Capital Territory, Nigeria. amaechitoexcel@yahoo.com
PENETRATING CRANIUM INJURY BY A CONCRETE NAIL: CASE STUDY
Authors: Al-Turki Ali Ali , Siamionau Viachaslau V. , Tsiatsiuyeu Andrei M. 
Published: January 2024

The article describes a case study, demonstrating the infliction of a single blind penetrating «gunshot» wound to the head with a concrete nail fired from a powder-actuated fastening tool. Forensic examination of the injury caused by atypical projectiles when fired from atypical firearms can be a difficult task. The results of a thorough autopsy examination of the body and the ante-/post-mortem discovery of atypical projectiles (or other foreign objects) in the victim’s body are the prerequisite for correct interpretation of the injury morphological features.

Peer Review History:
Received: 22 October 2023; Revised: 26 November; Accepted: 29 December, Available online: 15 January 2024
Academic Editor: Dr. Muhammad Zahid Iqbal, AIMST University, Malaysia, drmmziqbal@gmail.com
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewers:
Dr. Rima Benatoui,Laboratory of Applied Neuroendocrinology, Department of Biology, Faculty of Science, Badji Mokhtar University Annaba, Algeria. benattouiryma@gmail.com
Dr. Owanaro Peter, Nigeria, Department of Clinical Pharmacy and Pharmacy Practice, Faculty of Pharmacy, Niger Delta University, Wilberforce Island, Bayelsa State, Nigeria. owonaropeter@gmail.com
POSTMORTEM HEART DISSECTION FOR SUDDEN DEATH EXAMINATION
Authors: Al-Turki Ali Ali , Siamionau Viachaslau V. , Tsiatsiuyeu Andrei M. 
Published: January 2024

The article describes the postmortem heart examination technique during a forensic autopsy of adults. The heart examination technique is based on the recommendations of scientific societies of pathologists, publications on autopsy techniques used in recent decades. The achievements of morphologists of the second half of the 20th century are also taken into account. The postmortem heart examination technique provides an examination of the coronary vessels, as well as myocardium and heart valves. The possibilities for examination of the elements of the conductive system are also represented. The following method ensures preservation of topographic relationships of morphological structures within the heart and possibility of its re-examination. The postmortem heart examination includes the following stages: examination of the coronary arteries, the making of three transverse incisions from the apex to the middle of the ventricles, “blood flow” incisions taking into account the localization of the main nodes of the conducting system, as well as the peculiarities of the examination of the heart valves.

Peer Review History:
Received: 12 October 2023; Revised: 21 November; Accepted: 27 December, Available online: 15 January 2024
Academic Editor: Dr. Nuray Arı, Ankara University, Turkiye, ari@ankara.edu.tr
Received file: Reviewer's Comments:
Average Peer review marks at initial stage: 6.0/10
Average Peer review marks at publication stage: 7.0/10
Reviewers:
Prof. Hassan A.H. Al-Shamahy, Sana'a University, Yemen, shmahe@yemen.net.ye
Dr. Rima Benatoui,Laboratory of Applied Neuroendocrinology, Department of Biology, Faculty of Science, Badji Mokhtar University Annaba, Algeria. benattouiryma@gmail.com
Dr. Bilge Ahsen KARA, Ankara Gazi Mustafa Kemal Hospital, Turkey, ahsndkyc@gmail.com
Analisis Pemasaran Berbasis Media Sosial: Antecedents dan Consequences
Authors: Brianna Ni Kadek , M Ni Wayan Rena , Febianti Febianti 
Published: January 2024

Bajra Bali Villa Seminyak merupakan salah satu villa yang mengalami penurunan occupancy selama pandemi COVID-19. Persaingan antar villa yang semakin ketat, serta keterbatasan biaya untuk melakukan kegiatan promosi seperti sales call menyebabkan kesulitan peningkatkan brand awareness pada Bajra Bali Villa Seminyak. Salah satu strategi yang tepat digunakan saat ini adalah melalui media sosial. Penelitian ini bertujuan untuk menganalisis antecendents dan consequences dari strategi pemasaran melalui media sosial dalam meningkatkan brand awareness terkait penggunaan 5 aspek pemasaran berbasis sosial media yakni Customer Engagement, Viral Marketing, Buzz Marketing, Peer Influence, dan Online Community. Metode penelitian yang digunakan adalah kualitatif deskriptif dengan teknik pengumpulan data yaitu, dokumentasi, wawancara, dan observasi. Berdasarkan penelitian yang dilakukan, dari kelima aspek media sosial tersebut terbukti dapat meningkatkan kesadaran merek Bajra Bali Villa Seminyak dari tingkat unaware of brand menjadi tingkat brand recognition. Penelitian ini menunjukkan bahwa penggunaan kelima aspek pemasaran melalui sosial media efektif dalam meningkatkan brand awareness dari Bajra Bali Villa Seminyak selama pandemi COVID-19. Dari kelima aspek strategi pemasaran tersebut Buzz Marketing memberikan dampak yang lebih kuat dibandingkan aspek lainnya.

Bajra Bali Villa Seminyak is one of the villas that got occupancy decreased during the COVID-19 pandemic. The fierce competition between villas, as well as limited costs for carrying out promotional activities such as sales calls have made it difficult to increase brand awareness at Bajra Bali Villa Seminyak. One of the strategies that recently used is social media. This study aims to analyze antecendents and consequences from social media marketing strategies in increasing brand awareness related to the use of 5 aspects of marketing through social media, namely Customer Engagement, Viral Marketing, Buzz Marketing, Peer Influence, and Online Community. The research method used is descriptive qualitative with data collection techniques, namely, documentation, interviews, and observations. Based on the research, the five aspects of social media are proven to increase brand awareness of Bajra Bali Villa Seminyak from unaware of brand level to brand recognition level. This study shows that the use of the five aspects of marketing through social media is effective in increasing brand awareness of Bajra Bali Villa Seminyak during the COVID-19 pandemic. Among the five aspects of the marketing strategy, Buzz Marketing has a stronger impact than other aspects.
Pengaruh Budaya Organisasi dan Pemberian Kompensasi Terhadap Kepuasan Kerja Karyawan Hotel
Authors: Pulasari Putu Gede Kresna Jananda , Sudjana I Made , Sudarmawan I Wayan Eka 
Published: January 2024

Kepuasan Karyawan sangat penting bagi perkembangan produktivitas perusahaan itu sendiri. Tujuan penelitian ini untuk mengetahui signifikansi pengaruh Budaya Organisasi dan Kompensasi Terhadap Kepuasan Kerja Karyawan secara simultan maupun parsial. Populasi dalam penelitian ini sebanyak 64 responden diambil keseluruhannya. Pengujian hipotesis ini dilakukan pada tingkat signifikansi 5%. Hasil penelitian menunjukkan bahwa secara secara bersama-sama budaya organisasi dan kompensasi berpengaruh positif dan signifikan terhadap kepuasan. Secara parsial budaya organisasi berpengaruh positif dan signifikan terhadap kepuasan kerja. Diikuti dengan variabel kompensasi berpengaruh positif dan signifikan terhadap kepuasan. Berdasarkan penelitian ini perusahaan diharapkan dapat meningkatkan kepuasan kerja karyawannya dalam bentuk menambahkan uang overtime atau bonus maupun reward dan lebih meningkatkan pelaksanaan budaya organisasi.

Employee satisfaction is very important for the development of the productivity of the company itself. The purpose of this study was to determine the significance of the influence of Organizational Culture and Compensation on Employee Job Satisfaction simultaneously or partially. The population in this study as many as 64 respondents taken in its entirety. This hypothesis testing was carried out at a significance level of 5%. The results showed that together organizational culture and compensation had a positive and significant effect on satisfaction. Partially, organizational culture has a positive and significant effect on job satisfaction. Followed by the variable compensation has a positive and significant effect on satisfaction. Based on this research, the company is expected to increase the job satisfaction of its employees in the form of adding overtime money or bonuses or rewards and further improving the implementation of organizational culture.
Strategi Pelayanan Pramusaji dan Kepuasan Tamu
Authors: Madani Putu Gede , Arnawa I Gst Made Suka , Widhyadanta I Gede Dirga Surya Arya 
Published: January 2024

Ongan Restoran adalah restoran yang terletak di Desa Kesiman, Denpasar Timur, dengan konsep Balinese contemporare, restoran ini memadukan arsitektur khas Bali tanpa mengilangkan kesan modern di dalamnya. Penelitian ini bertujuan untuk mengetahui bagaimana faktor kualitas pelayanan, kualitas produk dan harga dalam meningkatkan kepuasan tamu di Warung Oongan dan untuk mengetahui pengembangan strategi pelayanan pramusaji yang tepat diterapakan dalam upaya meningkatkan kepuasan tamu yang berkunjung ke Warung Oongan.Teknik pengumpulan data menggunakan studi dokumentasi, observasi, wawancara dan angket. Teknik analisis data yang digunakan yaitu Analisis SWOT. Hasil penelitian menggunakan analisis SWOT menghasilkan Kuadran 1 yaitu Expansion, dimana strategi umum yang dapat dilakukan adalah memanfaatkan peluang yang ada dan kekuatan yang dimliiki sebesar-besarnya atau semaksimal mungkin. Berdasarkan analisi SWOT yang sudah dilakukan maka strategi umum yang dapat di lakukan oleh Warung Ongan adalah memaksimalkan kekuatan internal dan peluang eksternal yang dimiliki dalam meningkatkan kunjungan tamu dan kepuasan tamu yang datang ke Warung Ongan.

Ongan Restaurant is a restaurant located in Kesiman Village, East Denpasar, with a contemporary Balinese concept, this restaurant combines typical Balinese architecture without eliminating the modern impression in it. This research aims to find out how factors of service quality, product quality and price in increasing guest satisfaction at Warung Oongan and to find out the development of appropriate waiter service strategies implemented in an effort to increase the satisfaction of guests visiting the Warung Oongan. Data collection techniques use documentation studies, observation, interviews and questionnaire. The data analysis technique used is SWOT analysis. Research results using SWOT analysis produces Quadrant 1, namely Expansion, where the general strategy can be What is done is to make the most of existing opportunities and the strengths they have or as much as possible. Based on the SWOT analysis that has been carried out, a general strategy can be obtained What Warung Ongan can do is maximize internal strengths and opportunities external capabilities in increasing guest visits and satisfaction of guests who come to Ongan's Warung.