bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Phone Pal to overcome social isolation in patients with psychosis—Findings from a feasibility trial
Authors: Pinto da Costa Mariana , Virdi Kirat , Kouroupa Athanasia 
Published: January 2024

People with psychosis often experience social isolation due to stigma. Several volunteering programmes that exist in the community to support patients expect in-person meetings, requiring greater availability and commitment. This study investigated the acceptability and feasibility of remote volunteering over a smartphone for people with psychosis over 12 weeks, exploring its potential impact on both patients and volunteers. A total of 36 participants took part in the study. In the first phase, six participants were recruited in less than three weeks in London. All established contact with their match, and there were no study withdrawals. In the second phase, 30 additional participants were recruited in four weeks, across the United Kingdom. Most patients and volunteers reported that they primarily used audio calls to make contact, followed by text messages, WhatsApp messages and video calls. There were improvements in patients’ scores of quality of life, self-esteem, social contacts and symptoms, and in volunteers’ ratings of quality of life, physical activity, self-esteem, social comparison, and social distance towards people with mental illness. This study demonstrates that it is feasible, acceptable and safe to remotely connect volunteers and people with psychosis who are afar.
Trial registration: ISRCTN17586238 (registration date: 28/09/2018).
Autism Caregiver Coaching in Africa (ACACIA): Protocol for a type 1-hybrid effectiveness-implementation trial
Authors: Franz Lauren , Viljoen Marisa , Askew Sandy , Brown Musaddiqah , Dawson Geraldine , Di Martino J. Matias , Sapiro Guillermo , Sebolai Katlego , Seris Noleen , Shabalala Nokuthula , Stahmer Aubyn , Turner Elizabeth L. , de Vries Petrus J. 
Published: January 2024

Background
While early autism intervention can significantly improve outcomes, gaps in implementation exist globally. These gaps are clearest in Africa, where forty percent of the world’s children will live by 2050. Task-sharing early intervention to non-specialists is a key implementation strategy, given the lack of specialists in Africa. Naturalistic Developmental Behavioral Interventions (NDBI) are a class of early autism intervention that can be delivered by caregivers. As a foundational step to address the early autism intervention gap, we adapted a non-specialist delivered caregiver coaching NDBI for the South African context, and pre-piloted this cascaded task-sharing approach in an existing system of care.

Objectives
First, we will test the effectiveness of the caregiver coaching NDBI compared to usual care. Second, we will describe coaching implementation factors within the Western Cape Department of Education in South Africa.

Methods
This is a type 1 effectiveness-implementation hybrid design; assessor-blinded, group randomized controlled trial. Participants include 150 autistic children (18–72 months) and their caregivers who live in Cape Town, South Africa, and those involved in intervention implementation. Early Childhood Development practitioners, employed by the Department of Education, will deliver 12, one hour, coaching sessions to the intervention group. The control group will receive usual care. Distal co-primary outcomes include the Communication Domain Standard Score (Vineland Adaptive Behavior Scales, Third Edition) and the Language and Communication Developmental Quotient (Griffiths Scales of Child Development, Third Edition). Proximal secondary outcome include caregiver strategies measured by the sum of five items from the Joint Engagement Rating Inventory. We will describe key implementation determinants.

Results
Participant enrolment started in April 2023. Estimated primary completion date is March 2027.

Conclusion
The ACACIA trial will determine whether a cascaded task-sharing intervention delivered in an educational setting leads to meaningful improvements in communication abilities of autistic children, and identify implementation barriers and facilitators.

Trial registration
NCT05551728 in Clinical Trial Registry (https://clinicaltrials.gov).
Bruceine D and Narclasine inhibit the proliferation of breast cancer cells and the prediction of potential drug targets
Authors: Chen Xinhao , Li Hua 
Published: January 2024

Background
Breast cancer is one of the most common female malignancies. This study explored the underlying mechanism through which the two plant compounds (Brucaine D and Narclasine) inhibited the proliferation of breast cancer cells.

Objective
The purpose of this study was to explore the effect of Brucaine D and Narclasine on breast cancer development and their potential drug targets.

Methods
GSE85871 dataset containing 212 samples and the hallmark gene set “h.all.v2023.1.Hs.symbols.gmt” were downloaded from the Gene Expression Omnibus (GEO) database and the Molecular Signatures Database (MSigDB) database, respectively. Principal component analysis (PCA) was applied to classify clusters showing similar gene expression pattern. Single sample gene set enrichment analysis (ssGSEA) was used to calculate the hallmark score for different drug treatment groups. The expressions of genes related to angiogenesis, glycolysis and cell cycle were detected. Protein-protein interaction (PPI) network analysis was performed to study the interaction of the hub genes. Then, HERB database was employed to identify potential target genes for Narclasine and Bruceine D. Finally, in vitro experiments were conducted to validate partial drug-target pair.

Results
PCA analysis showed that the significant changes in gene expression patterns took place in 6 drugs treatment groups (Narciclasine, Bruceine D, Japonicone A, 1beta-hydroxyalatolactone, Britanin, and four mixture drugs) in comparison to the remaining drug treatment groups. The ssGSEA pathway enrichment analysis demonstrated that Narciclasine and Bruceine treatments had similar enriched pathways, for instance, suppressed pathways related to angiogenesis, Glycolysis, and cell cycle, etc.. Further gene expression analysis confirmed that Narciclasine and Bruceine had a strong ability to inhibit these cell cycle genes, and that MYC, CHEK2, MELK, CDK4 and EZH2 were closely interacted with each other in the PPI analysis. Drug target prediction revealed that Androgen Receptor (AR) and Estrogen Receptor 1 (ESR1) were the targets for Bruceine D, and Cytochrome P450 3A4 enzyme (CYP3A4) was the target for Narciclasine. Cell experiments also confirmed the connections between Narciclasine and CYP3A4.

Conclusion
The present study uncovered that Narciclasine and Bruceine D could inhibit the growth of breast cancer and also predicted the potential targets for these two drugs, providing a new therapeutic direction for breast cancer patients.
Preparation and performance of stainless steel fiber/Lyocell fiber-blended weft-knitted fabric
Authors: Yan Taohai , Wu Yingzi , Li Renzhi , Wu Yongze , Shi Yajing , Huang Luming , Chen Zhi 
Published: January 2024

Abstract
Stainless steel fiber exhibits excellent flame retardancy and melting resistance, but it lacks thermal and moisture comfort. To compensate for these shortcomings, stainless steel fiber was blended with Lyocell fiber in ratios of 0/100, 10/90, 20/80, and 30/70%. The blended yarn was then formed into a single-sided plain stitch fabric of stainless steel fiber and finished with a phosphorus–nitrogen flame retardant. Next, the effects of the blending ratio on the fundamental properties, thermal and moisture comfort, and flame retardancy of the blended yarn and its fabric were studied. Considering these parameters alongside cost, the 10% stainless steel fiber-blended fabric was the optimal choice and showed potential applications for updating and upgrading welding service fabrics.
Non-traditional Diplomacy and the Construction of China-Arab Community With a Shared Future
Authors: Liu Chen 
Published: January 2024

Abstract
Compared with the traditional diplomacy based on the behavior of national leaders and professional diplomats, non-traditional diplomacy relies on more diverse actors such as political officials, well-known scholars, academic institutions, business elites, ethnic groups, and media organizations to carry out strategic communication, policy interpretation, agenda setting and other practices with the people of other countries, so as to achieve the purpose of guiding public opinion and influencing government decision-making. During the development of relations between China and Arab countries, non-traditional diplomatic practices carried out in the form of government public relations, international communication, people-to-people exchanges, cultural and educational exchanges, which has effectively promoted policy communication, people-to-people and conceptual exchanges between China and Arab states. With the continuous deepening of the joint construction of the Belt and Road Initiative, non-traditional diplomacy will play a positive role in enhancing political trust, promoting economic and trade benefits, and fostering mutual appreciation of civilization, to expand the practical path, innovate the institutional mechanism and consolidate the foundation of public opinion for the construction of China-Arab community with a shared future.
The Study on Efforts of Chinese Education Reform
Authors: Zidane Ahmed 
Published: January 2024

Abstract
Confucianism imposes a great influence on Chinese ongoing educational reform. Based on Confucianism, Chinese education presented a lot of characteristics in line with the social needs and era characteristics. This paper reviews the development course of Chinese educational reform from the era of Confucius to new culture movement, from the founding of the People’s Republic of China to the Eighteenth National Congress of the Communist Party of China in 2012, which marked China’s entry into a new era, and summarizes the essential characteristics, achievements, and challenges in the reform. It indicates that the goal of all these educational reforms is to continuously reform and improve the education system and make it in line with the emerging conditions and lived reality, in order to build a society of truth, goodness, and hard work.
Neurofilament light protein as a biomarker for spinal muscular atrophy: a review and reference ranges
Authors: Bayoumy Sherif , Verberk Inge M.W. , Vermunt Lisa , Willemse Eline , den Dulk Ben , van der Ploeg Ans T. , Pajkrt Dasja , Nitz Elisa , van den Hout Johanna M.P. , van der Post Julie , Wolf Nicole I. , Beerepoot Shanice , Groen Ewout J.N. , Tüngler Victoria , Teunissen Charlotte E. 
Published: January 2024

Abstract
Spinal muscular atrophy (SMA) is the leading genetic cause of infant mortality, characterized by progressive neuromuscular degeneration resulting from mutations in the survival motor neuron (SMN1) gene. The availability of disease-modifying therapies for SMA therapies highlights the pressing need for easily accessible and cost-effective blood biomarkers to monitor treatment response and for better disease management. Additionally, the wide implementation of newborn genetic screening programs in Western countries enables presymptomatic diagnosis of SMA and immediate treatment administration. However, the absence of monitoring and prognostic blood biomarkers for neurodegeneration in SMA hinders effective disease management. Neurofilament light protein (NfL) is a promising biomarker of neuroaxonal damage in SMA and reflects disease progression in children with SMA undergoing treatment. Recently, the European Medicines Agency issued a letter of support endorsing the potential utilization of NfL as a biomarker of pediatric neurological diseases, including SMA. Within this review, we comprehensively assess the potential applications of NfL as a monitoring biomarker for disease severity and treatment response in pediatric-onset SMA. We provide reference ranges for normal levels of serum based NfL in neurologically healthy children aged 0–18 years. These reference ranges enable accurate interpretation of NfL levels in children and can accelerate the implementation of NfL into clinical practice.
Living a storied life: An interview with Mike Baynham
Authors: Gintsburg Sarali , Baynham Mike 
Published: January 2024

Abstract
Mike Baynham is Emeritus Professor of TESOL at the University of Leeds, a fellow of the Academy of Social Sciences and former Chair of the British Association for Applied Linguistics (BAAL). He was a Visiting Professor at York St John University (2020–2023) and an Honorary Professor at the University of Sydney (2019–2022). His recent publications include: Narrating Migrations from Africa and the Middle East: A Spatio-Temporal Approach (with R. Breeze and S. Gintsburg, Bloomsbury, 2022) and Translation and Translanguaging (with T. K. Lee, Routledge, 2019). In retirement he has become engaged with writing and translating poetry and various types of performance. He translates from Spanish and Arabic mainly and has published translations of the poetry of the Moroccan poet Abdallah Zrika (Baynham 2020). He is currently translating the poetry of the Moroccan zajal poet Adil Latefi and the Kurdish Syrian poet Ceger Hillo. His translation of a poem by Adil was awarded second prize in the 2023 Stephen Spender Poetry Competition. He works as a poetry editor at The Other Side of Hope magazine, setting up a bilingual poetry section, working title Other Tongue/Mother Tongue. In this interview, Mike first elaborates on the reasons behind his involvement with narrative studies and how it became clear that the Labovian model of narrative is not always valid with all types of narrative data. He then reflects on the definition of narrative, the role space and time have in it and offers, as an example of non-linear narrative a “picaresque” story, in the Arab tradition of storytelling. In conclusion Mike offers his vision of the future of narrative studies.
Whose uncertainty? Addressing the intersectional reader through the wound of trauma
Authors: Park Sowon S. 
Published: January 2024

Abstract
Few measures are more emblematic of the desire to curb uncertainty than trigger warnings issued in the literary classroom. But do they establish more certainty? A growing body of empirical research is showing that trigger warnings are “functionally inert.” Furthermore, in some studies they have been shown to increase PTSD symptoms. Against this background, this paper takes the rise in demand for trigger warnings as a window into Gen Z reader’s relationship to uncertainty and directs attention to the problem that trigger warnings aim to mitigate but are failing to alleviate – an “epidemic of trauma” in the classroom, as identified by the US National Council of State Education Association (NCSEA). Illuminating trauma as a neglected issue in narrative studies, this paper takes an intersectionally situated perspective to reappraise general propositions about the Reader in order to move towards a trauma-informed approach to teaching narrative in the classroom.
Getting out of history: Levitation and paralysis in Sebald and Nabokov
Authors: Biti Vladimir 
Published: January 2024

Abstract
Nabokov and Sebald confronted the dark sides of their national histories and tried to exempt themselves from them. Nabokov liberated himself from its burden by escaping into levitation, whereas Sebald’s willing exposure to its consequences ended in paralysis. Nabokov appears in his Emigrants as the equivocal figure of the ‘butterfly man’ who is simultaneously mobilizing and immobilizing. This is like the Russian writer himself, who used to adopt butterflies’ metamorphoses as a writer and paralyze them as a lepidopterist. Contrary to him, Sebald was horrified by their immobilization and sincerely empathized with them. Eluding the detached position of an ultimate authority and making his author deeply attached to all kinds of ‘nocturnal’ creatures, he created an unreliable but indispensable narrative agency. If Nabokov was at pains to deaden the uneasy memories of his past in order to relieve the present of their contamination, Sebald took the other way around, adhering to the most painful of them in order to enlighten their subterranean existence. He was committed to manifest these deeply buried remnants via his protagonists and narrators, however this amounted to the expulsion of those among them that had no other choice but to stick to life in darkness.
Shared-radiator design of broadband and dual-mode antenna for personal role radio applications
Authors: Wang Guanjun , Zhu Liang , Xie Yayun , Lu Chao 
Published: January 2024

Abstract
Shared-radiator design of a broadband and dual-mode antenna that simultaneously covers the VHF/UHF band and satellite navigation band is presented for personal role radio (PRR) applications. Quadrifilar helix antenna (QHA) is devised to be a circularly polarized radiator which as well acts as a part of the upper half radiation arm of the dipole antenna and be equivalent to a linearly polarized radiation current carrier at VHF/UHF band, forming a symmetrical dipole antenna with a sinusoidal current distribution. A 5th-order balanced matching network comprised of five cascade L-sections is adopted to obtain the maximum possible working band-width and a 3.76:1 band-width (116 %) at VHF/UHF band is achieved. Strong mutual coupling effect of the two operating modes is observed near 1.5 GHz originated from QHA shared-radiator design, and a new balun structure is applied to achieve high isolation and self-decoupling, subsequently |S21| of the two operating modes is significantly reduced from about −18 dB to below −32 dB at satellite navigation band without affecting the reflection coefficient and radiation efficiency. The measured results show that radiation patterns of the manufactured prototype is basically consistent with corresponding simulation counterparts.
De-chlorination of poly(vinyl) chloride using Fe2O3 and the improvement of chlorine fixing ratio in FeCl2 by SiO2 addition
Authors: Hong Lan , Li Tai-lin , Ye Lin-hai 
Published: January 2024

Abstract
A quantitative investigation of poly(vinyl) chloride (PVC) de-chlorination using Fe2O3, together with the impact of SiO2 addition on the co-pyrolysis of PVC and Fe2O3, was conducted below 673 K in an Ar atmosphere aiming to cut the emission of gaseous Cl⁻ products. It was found that chlorine in PVC can be fixed in FeCl2 by the reaction between PVC and Fe2O3. The co-pyrolysis of PVC and Fe2O3 proceeds in two stages with a temperature boundary of around 543 K. Below 543 K, a direct reaction occurs between PVC and Fe2O3, resulting in a small mass loss ratio and some extent of chlorine fixing ratio in FeCl2. However, above 543 K, PVC starts to decompose to release gaseous H2, HCl, etc., which react with Fe2O3 through two possible pathways to form FeCl2. In Pathway 1, first Fe2O3 is reduced to Fe3O4 by H2, followed by the chlorination of Fe3O4 to FeCl2 by HCl. In Pathway 2, first Fe2O3 is chlorinated to FeCl3 by HCl, followed by the reduction of FeCl3 to FeCl2 by H2. The chlorine fixing ratio in FeCl2 and the volatile generation ratio increase with decreasing PVC content in the initial mixtures. The addition of SiO2 promotes the chlorine fixing ratio in FeCl2 and volatile generation, and the impact gets stronger with decreasing PVC content in the mixtures. The chlorine fixing ratio is increased from 70.8 to 82.6% by SiO2 addition for the mixtures containing 25% PVC, whereas the difference in the chlorine fixing ratio in FeCl2 caused by SiO2 addition is negligible for the mixtures containing 90% PVC. Fayalite (Fe2SiO4) was not detected in the solid residues after the experiments. After separating FeCl2 using water leaching, the filter residue, a composite of iron oxide and conjugated polyene, can be used as a raw material for iron-making.
Review of ocular alterations in bats in America and notes on a new case for Saccopteryx bilineata (Chiroptera: Emballonuridae)
Authors: Herazo-Callejas Sebastián , Parejo-Tovar Miguel , Chacón-Pacheco Julio J. 
Published: January 2024

Abstract
Morphological abnormalities in bats are rarely reported and, particularly, ocular problems are relatively scarce in the literature. We present a review of the records of ocular alterations in bats of the American continent and document for the first time a case of ocular alteration in the species Saccopteryx bilineata in northern Colombia. In this study we found cases of corneal opacity (5/19 individuals), lesions and trauma, microphthalmia (4/19 individuals), anophthalmia (4/19 individuals) and adnexal diseases (2/19 individuals). We encourage researchers to report their observations of bats with ocular anomalies, as this information could be useful for estimating occurrence rates and addressing questions associated with the social behaviour of the species and on their effects on natural populations.
Inverse design of compact nonvolatile reconfigurable silicon photonic devices with phase-change materials
Authors: Wei Maoliang , Lin Xiaobin , Xu Kai , Wu Yingchun , Wang Chi , Wang Zijia , Lei Kunhao , Bao Kangjian , Li Junying , Li Lan , Li Erping , Lin Hongtao 
Published: January 2024

Abstract
In the development of silicon photonics, the continued downsizing of photonic integrated circuits will further increase the integration density, which augments the functionality of photonic chips. Compared with the traditional design method, inverse design presents a novel approach for achieving compact photonic devices. However, achieving compact, reconfigurable photonic devices with the inverse design that employs the traditional modulation method exemplified by the thermo-optic effect poses a significant challenge due to the weak modulation capability. Low-loss phase change materials (PCMs) exemplified by Sb2Se3 are a promising candidate for solving this problem benefiting from their high refractive index contrast. In this work, we first developed a robust inverse design method to realize reconfigurable silicon and phase-change materials hybrid photonic devices including mode converter and optical switch. The mode converter exhibits a broadband operation of >100 nm. The optical switch shows an extinction ratio of >25 dB and a multilevel switching of 41 (>5 bits) by simply changing the crystallinity of Sb2Se3. Here, we experimentally demonstrated a Sb2Se3/Si hybrid integrated optical switch for the first time, wherein routing can be switched by the phase transition of the whole Sb2Se3. Our work provides an effective solution for the design of photonic devices that is insensitive to fabrication errors, thereby paving the way for high integration density in future photonic chips.
Omega: Beziehungsgefüge und Organisationsformen einer künstlerischen Formation im frühen 20. Jahrhundert
Authors: Söntgen Beate 
Published: January 2024

Abstract

Der Beitrag untersucht die Formation, also gleichermaßen die Genese und die Gestalt der Londoner Werkstatt ‚Omega‘ im frühen 20. Jahrhundert, die aus dem Bloomsbury Kreis hervorgegangen ist. Es handelt sich um einen dichten Zusammenhang von Lebens-, Arbeits- und Gestaltungsformen und das Zusammenspiel von affektiven und instrumentellen Beziehungsweisen auch in der Organisationsform, die durch weitgehende Strukturlosigkeit gekennzeichnet ist. Wie sich vor diesem Hintergrund Prozesse der Konstituierung, der Entscheidungsfindung und der oft verdeckten Hierarchiebildung in künstlerischen Gemeinschaften nachvollziehen lassen, wird vor der Folie der gegenwärtigen Diskussion um Kollektive entfaltet.