bluuebunny/crossref_metadata_2025_split huggingface dataset:
Folic acid supplementation during preconception period in sub-Saharan African countries: A systematic review and meta-analysis
Authors: Aweke Mekuriaw Nibret , Fentie Elsa Awoke , Agimas Muluken Chanie , Baffa Lemlem Daniel , Shewarega Ever Siyoum , Belew Aysheshim Kassahun , Muhammad Esmael Ali , Mengistu Berhanu 
Published: January 2025

Introduction
Neural tube defects (NTDs) are serious congenital anomalies of the central nervous system caused by disruptions in early embryonic development. The prevalence is about twice as common in low- and middle-income countries and more prevalent in sub-Saharan Africa. Folic acid deficiency is a major risk factor and common during pregnancy. However, limited research on preconception folic acid supplementation in this region highlights the need for systematic reviews and targeted interventions to improve maternal and fetal health.

Methods
We conducted a systematic literature search in EMBASE, MEDLINE, Scopus, CINAHL, Google Scholar, and Google for studies on the proportion of folic acid supplementation during the preconception period, covering publications up to January 2024. Study quality was assessed using the Newcastle-Ottawa Scale. Heterogeneity was evaluated with Cochrane Q and I2 statistics, and small study effects were tested with Egger’s test at a 5% significance level. The certainty of evidence was assessed using the GRADE approach. A random-effects model was used to estimate the pooled proportion of FA supplementation during the preconception period in sub-Saharan African countries.

Result
This systematic review included 28 studies with a total of 12,562 participants. The highest (45.2%) and lowest (1.9%) proportion of folic acid supplementation during preconception period were recorded in the southern and Amhara regions of Ethiopia, respectively. The estimated pooled proportion of folic acid supplementation among women in Sub-Saharan Africa (SSA) during preconception period was (14.10%; 95% CI: 11.22–16.98) with significant heterogeneity between studies (I2 = 97.71%, p = 0.001). In sub-group analysis based on corresponding countries the highest estimated folic acid supplementation proportion during preconception period was found in studies conducted in Kenya ((22%; 95% CI: 19%-25%), I2 = 97.7%), followed by studies conducted in Ghana (20%; 95% CI: 7%-33%), I2 = 96.9%). The majority of the studies included in the analysis are of high quality, with quality scores ranging from 7 to 8. The certainty of evidence was assessed using the GRADE approach, resulting in a low overall rating.

Conclusion
The results of this systematic review and meta-analysis indicated that folic acid supplementation during preconception period is significantly low among mothers in sub-Saharan African countries, despite being one of the best approaches to improve birth outcomes. Therefore, healthcare organizations, governments, policymakers, and other stakeholders involved in folic acid supplementation must collaborate on developing strategies to improve its uptake during the preconception period.
Design and application of soft robot grippers using low-viscosity silicone by lost core injection molding manufacturing method
Authors: Bryantono Helmy Dewanto , Tsai Meng-Hsun , Tseng Shi-Chang 
Published: January 2025

Abstract
This project aims to develop a manufacturing method for a newly designed soft robot gripper in one shot by utilizing a low-viscosity liquid silicone rubber (LSR) lost-core injection molding embedded with a polyvinyl alcohol (PVA) water-soluble core inside. Due to the relatively high viscosity of LSR, higher injection pressures were needed to complete the mold-filling process. This, in turn, resulted in a washout of the PVA lost core. Therefore, this study used a lower viscosity of LSR and pressure to avoid this problem. Ansys structural analysis simulation was used to get the experiment variables and then compare them with the real experiment results. The maximum pressure employed in the simulation of the gripper bending is 30 kPa with 119.38 mm, while the experimental is 112.65 mm total deformation. Finally, the washout of the lost core, the bending restriction problem, and the complicated manufacturing problems in this area were tackled in this study. The design of a finger with a greater angle at the edge and the use of low-viscosity LSR as the primary material in a one-shot lost core LSR injection molding method are extensions from previous studies that are believed to be valuable inventions for academic and practical applications.
Local differences in network organization in auditory and parietal cortex, revealed with single neuron activation
Authors: Khoury Christine F. , Ferrone Michael , Runyan Caroline A. 
Published: January 2025

The basic structure of local circuits is highly conserved across the cortex, yet the spatial and temporal properties of population activity differ fundamentally in sensory-level and association-level areas. In sensory cortex, population activity has a shorter timescale and decays sharply over distance, supporting a population code for the fine-scale features of sensory stimuli. In association cortex, population activity has a longer timescale and spreads over wider distances, a code that is suited to holding information in memory and driving behavior. We tested whether these differences in activity dynamics could be explained by differences in network structure. We targeted photostimulations to single excitatory neurons of layer 2/3, while monitoring surrounding population activity using two-photon calcium imaging. Experiments were performed in auditory (AC) and posterior parietal cortex (PPC) within the same mice of both sexes, which also expressed a red fluorophore in somatostatin-expressing interneurons (SOM). In both cortical regions, photostimulations resulted in a spatially restricted zone of positive influence on neurons closely neighboring the targeted neuron, and a more spatially diffuse zone (akin to a network-level ‘suppressive surround’) of negative influence affecting more distant neurons. However, the relative spatial extents of positive and negative influence were different in AC and PPC. In PPC, the central zone of positive influence was wider, but the negative suppressive surround was more narrow than in AC, which could account for the larger-scale network dynamics in PPC. The more narrow central positive influence zone and wider suppressive surround in AC could serve to sharpen sensory representations.Significance StatementThe basic structure of local circuits is highly conserved across the cortex, and yet local processing goals vary across the sensorimotor hierarchy, from sensory perception to the control of behavior. It has been unclear whether these differences in function require different network organization. To probe the spatial structure of networks in sensory and association-level cortex, we photostimulated single excitatory neurons and measured the effect on local population activity in mice. Stimulations triggered a centered, positive activity change in neighboring neurons, and a surrounding, suppressive change in more distant neurons. The relative sizes of the center and surround differed across areas, suggesting that network structure is tailored for sharper, more restricted activity in sensory cortex, and more dense network activity in association cortex.
Higher prevalence of gestational diabetes in euthyroid women with thyroid autoimmunity who were expecting a female fetus
Authors: Prasai Madhu , Lomré Manon , Jelloul Emna , Kleynen Pierre , Veltri Flora , Sitoris Georgiana , Grabczan Lidia , Rozenberg Serge , Poppe Kris G 
Published: January 2025

Objective
In the general population, women pregnant with a male fetus (MF) have a higher prevalence of gestational diabetes mellitus (GDM) compared with those pregnant with a female fetus (FF). Some studies suggest a higher prevalence of GDM in euthyroid pregnant women with thyroid autoimmunity (TAI+) compared with women without TAI (TAI−). However, whether the impact of TAI on GDM correlates with fetal gender has not been documented.

Design/methods
A single-center cohort study including 1201 women who were screened at a median of 12 (11–14) weeks of pregnancy for thyroid disorders (TSH, free T4 and thyroid peroxidase antibodies (TPOAb)) and at 24–28 weeks for GDM with an oral glucose tolerance test. Exclusion criteria were pre-pregnancy diabetes or hypertension, thyroid dysfunction (treated or untreated) before and after screening, thyroid screening after 20 weeks of pregnancy and assisted pregnancies. The diagnosis of GDM was based on the 2013 WHO criteria, and that of TAI by increased TPOAb levels (≥60 kIU/L).

Results
Overall, 622 women were expecting a FF (51.8%) and 579 a MF (48.2%). Seventy-five women were TAI+ (6.2%). The overall prevalence of GDM was 19.6%, 28% in TAI+ women and 19% in TAI− women (P = 0.008 after adjustment for confounders). In women who were expecting a FF, the prevalence of GDM was 34.4% in TAI+ women vs 19.2% in TAI− women; P = 0.002.

Conclusions
The prevalence of GDM was increased in euthyroid TAI+ women, but only in the case of pregnancies with a FF. This is opposite to the result observed in the general population and deserves more research to explore the underlying mechanisms.
Skala projektów elektrowni fotowoltaicznych w Polsce – wstępne badanie geostatystyczne na podstawie bazy OOŚ
Authors: Pelczar Szymon 
Published: January 2025

Moc zainstalowana systemów fotowoltaicznych w Polsce systematycznie wzrasta. Choć w strukturze rodzajów jednostek wytwórczych tego typu dominują mikroinstalacje, to swój udział ustawicznie zwiększają także instalacje wielkoskalowe – elektrownie fotowoltaiczne. Systemy te nie pozostają bez wpływu na środowisko, a ich realizacja niejednokrotnie napotyka konflikty społeczne. Praca miała na celu oszacowanie skali elektrowni fotowoltaicznych w Polsce przy zastosowaniu danych dostępnych w bazie ocen oddziaływania na środowisko (z wykorzystaniem analizy geostatystycznej). Wyniki badania potwierdzają znacząca liczbę planowanych do realizacji elektrowni fotowoltaicznych, przy czym widoczne jest ich zróżnicowanie przestrzenne w skali regionalnej. Ponadto wynik analizy geostatystycznej dowodzi, że najliczniejszą grupę projektów stanowią te o mocy poniżej 20 MW. Pomimo stosunkowo małej liczby projektów o mocy powyżej 50 MW, mogą mieć one istotny wkład pod względem mocy zainstalowanej systemów fotowoltaicznych.
O herói das Argonáuticas latinas
Authors: Júnior Márcio Meirelles Gouvêa 
Published: January 2025

A partir do estudo sistemático dos quatro primeiros episódios das Argonautica, de Valério Flaco, torna-se possível determinar um elenco de virtudes características do principal herói da obra, Jasão. Essas virtudes, contudo, revelam-se adequadas às condições históricas, políticas e filosóficas da época em que o poema foi escrito, tornando-se, portanto, um modelo de excelência adequado ao cidadão romano no último quartel do século I.
“Homem do seu tempo e do seu país”
Authors: Lopes Elisângela Aparecida 
Published: January 2025

This article analyzes the established relations between the characters that represent masters, slaves, and freed men in Machado de Assis’ writtings. The analysis of the slavery and abolitionist themes and, above all, the identification of the discursive locus of these writings allow us to assert the writer’s involvement to the questions of his époque.
<i>Bufo &amp; Spallazanni</i>, diálogo entre literatura e cinema
Authors: Santos Karla Aparecida Marques 
Published: January 2025

A adaptação fílmica Bufo & Spallanzani é vista neste ensaio como um processo de transcriação, como uma nova experiência, que deve ter sua forma e conteúdo julgados em função de seu próprio campo – o cinema, em diálogo com o texto de origem e com seu contexto.
Escalas simples, cuerpos complejos ¿Cómo las medidas de una casa impactan los roles de género?
Authors: Noguerón Maldonado Lesly Yanely 
Published: January 2025

A house is more than just a collection of spaces, objects, and people; it is also shaped by hierarchies, roles, and tensions influenced by the broader context that permeates its boundaries and manifests in human relationships within it. Whether it is a room, an apartment, an anti-refuge, or a domain, these dynamics are ever-present. This research presents a quantitative analysis of the representation of gender roles in anthropometry and ergonomics manuals commonly used in design and architecture. In the manuals by Neufert, Fonseca, and Panero & Zenik, over 90% of service spaces in homes are depicted using graphic scales of women, while recreational and rest spaces predominantly feature men. This study critically examines how these representations reinforce structures of domination and highlights the need for more inclusive design alternatives.
O Movimento Docente na Universidade Federal do Pará: contra-poder frente à razão do Estado?
Authors: Jacob Chaves Vera Lúcia 
Published: January 2025

Este estudo tem por objetivo analisar a atuação do Movimento Docente (MD) organizado na UFPA no período de 1979 a 1994, no que tange às reivindicações e às conquistas locais. Ao resgatar o processo de organização e luta dos intelectuais universitários, constata-se que o Movimento se constitui em resistência (contra-poder) à razão do Estado e definiu políticas educacionais para a Universidade em âmbito local e nacional.
Differentiating of Sepsis-Associated and Sepsis-Induced Acute Kidney Injury in Intensive Care Unit Patients
Authors: Hotabilardus Nusi , Anggraeni Novita 
Published: January 2025

Introduction: Acute kidney injury (AKI) is a severe and common complication in Intensive Care Unit (ICU) patients, commonly resulting from sepsis. It is associated with elevated mortality, chronic renal failure, and other long-term consequences. Sepsis-associated AKI (SA-AKI) and Sepsis-induced AKI (SI-AKI), a specific sub-phenotype, differ in their underlying pathophysiology. Objective: To examine the distinctions between SA-AKI and SI-AKI, focusing on their pathophysiology, biomarkers for detection, and associated prognoses in critically ill patients. This literature review examines the findings of randomized control trials (RCTs) or meta-analysis studies that learn about biochemical mediators and biomarkers for SA-AKI and SI-AKI, including NGAL, Kim-1, and others, as well as the prognostic impact of these conditions. The literature was gathered from Google Scholar and PubMed using the keywords Sepsis-Associated Acute Kidney Injury, Sepsis-Induced Acute Kidney Injury, Intensive Care Unit, and Sepsis and published within the last ten years (2018–2023). Articles unavailable in the full text were excluded. Review: SA-AKI and SI-AKI are distinct entities within the broader spectrum of sepsis and AKI. SI-AKI involves sepsis-induced direct kidney damage, which differentiates it from other forms of SA-AKI. Various biomarkers such as NGAL, Kim-1, and others are crucial for early detection and differentiation between these conditions. Patients with SA-AKI and SI-AKI usually have a bad outlook. They are more likely to die, be disabled for a long time, and need longer stays in the ICU and hospital than patients with sepsis or AKI alone. Figuring out the underlying pathophysiology and using the right biomarkers can help with early diagnosis and could lead to better outcomes for patients through targeted therapies. Summary: SA-AKI and SI-AKI represent critical complications in ICU patients with sepsis, leading to high mortality and long-term adverse outcomes. Differentiating between these conditions using biomarkers is essential for early detection and management. These patients have a worse prognosis than those with sepsis or AKI alone. This shows how important it is to keep researching and finding better ways to treat these serious complications in critically ill patients.
DEKONSTRUKSI MAKNA “PRESTASI” PADA SISWA, GURU, DAN ORANG TUA SISWA
Authors: Urbaningrum Luhjingga Panasari , Martono Nanang , Puspitasari Elis , Kurniawan Agung 
Published: January 2025

<p><em>This study aims to challenge the traditional concept of achievement often defined merely as formal recognition. It seeks a broader and more inclusive understanding of achievement by acknowledging various forms of success and abilities possessed by students. The research methodology employed is qualitative research. Data were collected through three main techniques: in-depth interviews, direct observation, and documentation. Informants for the study were purposively selected to ensure they possessed relevant knowledge and experience on the research topic, consisting of three students, two teachers, and three parents of students. Data obtained were analyzed using Interactive Analysis techniques. The findings of the study indicate that the definition of achievement extends beyond academic accomplishments to include personal development, social skills, and the ability to overcome challenges. The implications of this research are crucial in supporting every child to reach their full potential and in fostering an inclusive and supportive educational environment. Every child deserves recognition for their achievements, not only in academic fields but also in the development of personal skills and values that prepare them for the future, thereby promoting a more inclusive paradigm shift in the assessment and recognition of student achievements</em><em>.</em></p><p> </p>
PENILAIAN GERAKAN BARIS-BERBARIS BERBASIS AI DAN LSTM PADA SELEKSI PASKIBRAKA
Authors: Asmoro Shandy Sadewa , Wulanningrum Resty , Sanjaya Ardi 
Published: January 2025

PASKIBRAKA member selection is conducted annually at three levels. PASKIBRAKA members must fulfil the criteria, one of which is the Marching Regulations (PBB). In the UN assessment process, sometimes the judges are still subjective. Therefore, it is necessary to have a system with artificial intelligence (AI) integration. The methods used in the system are Mediapipe and Long Short Term Memory (LSTM) algorithm. Mediapipe serves to display 33 keypoints and extract features from these keypoints which will later be processed by LSTM for motion detection. From the test results, the highest accuracy value of each movement is walking in place by 99%, striding by 95%, and regular steps by 97%. While the lowest accuracy value of each movement is walking in place by 12%, striding by 21%, and ordinary steps by 23%. The accuracy value is the result of the analysis of the LSTM model that has been made. The highest accuracy value in each movement comes from the correct movement, while the lowest accuracy value comes from the wrong movement. The accuracy results in the recognition of stride and ordinary steps are influenced by video movements during the transition of the right hand to the left hand which are still detected incorrectly because almost all movements when both hands are in the lower position, causing low accuracy values.Keywords: Keypoints, Long Short Term Memory, Marching, Mediapipe
From Caring to Killing: A Typology of Homicides and Homicide-Suicides Perpetrated by Caregivers
Authors: O'Dwyer Siobhan , Bishop Charlie , Gimson Rachel , Melendez-Torres G.J. , Stevens Daniel , Hardy Lorna 
Published: January 2025

Abstract

Background
Caregivers are people who provide essential care for family members or friends with long-term illnesses or disabilities. A growing body of research has shown that caregivers contemplate suicide at higher-than-average rates, with some also contemplating homicide (killing the person for whom they care) or homicide-suicide. Although anecdotal reports of caregiver-perpetrated homicides abound, the scholarly research has been fragmented and led to unsubstantiated claims (by policy makers and frontline professionals) that these are isolated tragedies that cannot be predicted or prevented. Typologies have been used to guide the study, prediction, and prevention of domestic homicides, but they do not adequately capture the diversity and complexity of caregiver-perpetrated homicides. The aim of this study was to develop a dedicated typology of caregiver-perpetrated homicides that could provide a framework for more rigorous research and facilitate targeted prediction and prevention initiatives.
Results
Ideal Type Analysis was applied to sixty-four homicides and homicide-suicides perpetrated by caregivers in England and Wales between January 2015 and December 2019. The cases clustered into seven clear Types: Ending Suffering; Genuine Burden of Care; Pre-Existing Mental Illness; Neglect; Exploitation; Caregiver as Victim of Domestic Violence, Abuse or Coercive Control; and, Caregiver as Perpetrator of Domestic Violence, Abuse, or Coercive Control. Each type was characterised by a distinct motive, context, or course of events leading to the homicide.
Conclusions
This is the first typology of homicides and homicide-suicides perpetrated by caregivers. It challenges claims that these are isolated events and highlights opportunities for prediction and prevention. The Caregiver-Perpetrated Homicide Typology also provides a framework for future research, including an exploration of the social, economic, and political contexts in which these homicides take place, and the development of evidence-based responses across the health, social care, and criminal justice sectors.
“Regeneration-Repair-Strengthening” mechanism in the oxidation film damage region of copper-nickel alloys under magnetic field effects
Authors: Gong Ke , Wang Jiamu , Hu Xiuqi , Yang Mingsi , Wang Yuanming , Mao Feixiong 
Published: January 2025

Abstract

Copper-nickel alloy pipes in marine environments are prone to scouring by solid particles, which disrupt the bilayer oxidation film and induce scratches. These scratched regions are more vulnerable to perforation, potentially leading to premature pipe failure. Thus, rapidly repairing the film and restoring its corrosion resistance is a major challenge. This study simulates the "film damage-regeneration" process of copper-nickel alloys in marine environments, researching the regeneration of the film in scratched regions of a 70/30 Cu-Ni alloy in a 3.5 wt% NaCl solution, under both non-magnetic and magnetic field conditions. The results demonstrate that the application of a magnetic field accelerates the regeneration of the film and, through synergistic interactions with the scratched microregions, alters the local pH conditions, suppresses the re-deposition of Cu<2/sup>O, and significantly enhances the enrichment of NiO on the surface of the regenerated film. Ultimately, a unique single-layer film structure with enhanced corrosion resistance is formed. Notably, this single-layer film structure represents the first reported observation in copper-nickel alloy studies. This work offers a novel approach for in-situ copper-nickel alloy pipeline's film repair, with significant implications for extending the lifespan of marine engineering infrastructures.
Di-p-coumaroyl spermidine from bee pollen alleviates chronic non- bacterial prostatitis
Authors: Dong Jie , Zhang Jiawen , Qiao Jiangtao , Zhang Yu , Zhu Hequan , Haubruge Eric , Liu Liqiang 
Published: January 2025

Abstract

Bee pollen and its extracts have been used for decades as therapeutic agents or health food supplements to alleviate chronic non-bacterial prostatitis (CNP). However, functional compounds in bee pollen on anti-CNP remain still unclear. In this study, we evaluated the anti-CNP properties of six principal phenolamides in bee pollen. Our results provide compelling evidence that the anti-CNP property of bee pollen may be ascribed to its abundance of phenolamides. Particularly, di-p-Coumaroyl spermidine can alleviate CNP by upregulating autophagy via the AMPK/mTOR signaling pathway and regulating gut microbiota, based on the cellular and rat models. Additionally, our finding may provide a novel insight into the gut-prostate axis by regulating di-p-Coumaroyl spermidine. This is the first report that di-p-Coumaroyl spermidine in bee pollen possesses the anti-prostatitis function. This paper will be likely helpful further to develop functional foods, personalized nutraceuticals, and medicine from bee pollen.