bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Dynamic Neuro-Fuzzy Model Providing Bio-State Estimation and Prognosis Prediction for Wearable Intelligent Assistants
Authors: Wang Yu , Winters Jack M 
Published: June 2005

Abstract

Background
Intelligent management of wearable applications in rehabilitation requires an understanding of the current context, which is constantly changing over the rehabilitation process because of changes in the person's status and environment. This paper presents a dynamic recurrent neuro-fuzzy system that implements expert-and evidence-based reasoning. It is intended to provide context-awareness for wearable intelligent agents/assistants (WIAs).

Methods
The model structure includes the following types of signals: inputs, states, outputs and outcomes. Inputs are facts or events which have effects on patients' physiological and rehabilitative states; different classes of inputs (e.g., facts, context, medication, therapy) have different nonlinear mappings to a fuzzy "effect." States are dimensionless linguistic fuzzy variables that change based on causal rules, as implemented by a fuzzy inference system (FIS). The FIS, with rules based on expertise and evidence, essentially defines the nonlinear state equations that are implemented by nuclei of dynamic neurons. Outputs, a function of weighing of states and effective inputs using conventional or fuzzy mapping, can perform actions, predict performance, or assist with decision-making. Outcomes are scalars to be extremized that are a function of outputs and states.

Results
The first example demonstrates setup and use for a large-scale stroke neurorehabilitation application (with 16 inputs, 12 states, 5 outputs and 3 outcomes), showing how this modelling tool can successfully capture causal dynamic change in context-relevant states (e.g., impairments, pain) as a function of input event patterns (e.g., medications). The second example demonstrates use of scientific evidence to develop rule-based dynamic models, here for predicting changes in muscle strength with short-term fatigue and long-term strength-training.

Conclusion
A neuro-fuzzy modelling framework is developed for estimating rehabilitative change that can be applied in any field of rehabilitation if sufficient evidence and/or expert knowledge are available. It is intended to provide context-awareness of changing status through state estimation, which is critical information for WIA's to be effective.
Randomized Controlled Trial of Tamoxifen in Advanced Hepatocellular Carcinoma
Authors: Barbare Jean-Claude , Bouché Olivier , Bonnetain Franck , Raoul Jean-Luc , Rougier Philippe , Abergel Armand , Boige Valérie , Denis Bernard , Blanchi Alain , Pariente Alexandre , Milan Chantal , Bedenne Laurent 
Published: June 2005

Purpose Randomized studies on tamoxifen treatment of hepatocellular carcinoma (HCC) produced conflicting results. The aim of this study was to assess the efficacy of tamoxifen administration in improving overall survival of patients with advanced HCC. Patients and Methods A total of 420 patients with HCC who were not suitable for surgery or local treatment were randomly assigned between April 1995 and May 2000: 210 in the control group and 210 in the tamoxifen group (20 mg/d orally). Patients with WHO performance status greater than 2, belonging to Child-Pugh class C, or with serum creatinine greater than 130 μmol/L were not eligible. Results Tolerance was good and the main reported adverse effects were thrombophlebitis (three patients), nausea (two patients), and hot flushes (three patients). Outcome did not differ between the two treatment arms: estimated median survival was 4.8 and 4.0 months in the tamoxifen and in the control groups, respectively (P = .25). Univariate analysis showed significant association of survival with age, Okuda stage, WHO performance status, Child-Pugh class, intrahepatic tumor stage, alpha-fetoprotein serum concentration, and presence of extrahepatic spread, portal vein thrombosis, hepatomegaly, or hepatalgia. In a Cox proportional hazards model we found a significant beneficial effect of tamoxifen on survival in patients belonging to Okuda I or II stages. Conclusion In this large study, tamoxifen did not improve the survival of patients with advanced HCC, but there is a suggestion that patients without major hepatic insufficiency seem to have some survival benefit. New trials involving this specific population are warranted.
Dry Chemistry Urinalysis of Pathological Proteinuria
Authors: Kutter Dolphe 
Published: June 2005

Abstract
The paper presents a review of the characteristics and analytical performance of the most current dry chemistry methods for detection and estimation of the different urinary proteins. Description of the classical “protein error” dipsticks for macroalbuminuria is supplemented by data on more sensitive alternatives based on the same principle, reaching into the zone of microalbuminuria. Immunological test strips are available for detection of low concentrations of albumin. Application of the same principle is attempted for detection of other specific proteins.
Highly sensitive enzymatic reactions allow detection of “lysis proteins”: haemoglobin, leukocyte esterase and β-N-acetyl-glucosaminidase.
An efficient strategy for screening for all types of pathological proteinuria based on detection of low albumin levels is presented.
European Multicentre Evaluation of the Super Aution SA-4220 Urinalysis Analyser
Authors: Galimany Román , Arambarri Marta , Biosca Carmen , Ceriotti Ferruccio , Chapelle Jean Pierre , Lopez Rosa , Souverijn John H. M. , Spagnuolo Giovanni , Scopacasa Francesco , Almirall Lourdes 
Published: June 2005

Abstract
A multicentre evaluation of the urine test strip analyser Super Aution-4220 was carried out in six laboratories. The analytical performance of the instrument with regard to imprecision, linearity, detection limit, drift, carry-over and method comparison was studied. Using the Aution stick 8 test strip the pH, glucose, protein, ketones, bilirubin, blood, urobilinogen and leukocyte esterase were analysed. Specific gravity measurements were performed by refractive index method. Within-run and between-run imprecision determined at three levels of analyte were good. No carry-over was observed. Obtained results were linear through all the described analytical range. No significant drift was detected. Method comparison with some quantitative methods was performed and showed a good correlation with most of the analytes. The study of interferences showed minor interferences by common therapeutic drugs with the measurement of some analytes. During the assessment period of about 6 months no breakdown occurred in any laboratory. The Super Aution urine analyser appeared to be a highly automated analyser of urinary test strips. The operation was simple and the maintenance required only a few minutes a day.
Evaluation of the Activated Partial Thrombo-plastin Time (APTT) Sensitivity to Heparin Using Five Commercial Reagents: Implications for Therapeutic Monitoring
Authors: Manzato Franco , Mengoni Alessandra , Grilenzoni Angela , Lippi Giuseppe 
Published: June 2005

AbstractHeparin is an effective drug for prevention and treatment of thromboembolic conditions. Although several biological assays have been proposed for monitoring unfractionated heparin therapy, the measurement of the activated partial thromboplastin time (APTT) is the most widely employed test, and the overall risk of thromboembolic episodes was markedly reduced by maintaining APTT ratios above 1.5. However, the adjustment of the heparin therapy on the basis of APTT presents several questions which are still unresolved. Major discrepancies were found in APTTs performed using different reagents in bothex vivoandin vitroheparinized samples and occasionally with different lots of the same reagents; poor correlation was observed between APTT values and plasma heparin concentrations. In order to gain further insights into this phenomenon, we analysed the sensitivity to heparin of five commercial reagents for APTT measurement in 19ex vivoheparinized samples. Differences were observed; correlation coefficients ranged from 0.820 to 0.985 and slopes of linear regressions from 0.26 to 1.14. Moreover, unsatisfactory correlations were obtained when APTT ratios were compared with heparin plasma concentrations in the same patients' samples. In the heparin therapeutic range of 0.35–0.70 U/ml, reagent-dependent differences were observed in the corresponding APTT values. These results point out a critical role of the assay methodology in monitoring heparin therapy by APTT. We suggest that reference materials and methods should be urgently identified, a universally agreed scale for reporting results should be established and reference ranges for the unfractionated heparin therapy should be reconsidered taking on account the reagent employed.
Polymethyl methacrylate/montmorillonite nanocomposite beads through a suspension polymerization‐derived process
Authors: Kim Sung Soo , Park Tae Sook , Shin Byung Cheol , Kim Young Baek 
Published: June 2005

AbstractPolymethyl methacrylate (PMMA) polymer beads with montmorillonite (MMT) were prepared using a suspension polymerization method for applying acrylic bone cements. The polymer beads were characterized by X‐ray diffraction and transmission electron microscopy to examine MMT dispersion. The change in the shape and size of the polymer beads due to the preparation conditions, such as stirring speed, degree of polymerization, and concentration of polyvinyl alcohol (PVA) as a suspension stabilizer, and MMT contents, etc. was observed by scanning electron microscopy and particle size analysis. The prepared polymer beads were composed of polymer‐intercalated nanocomposites with partially exfoliated MMT layers. The size of the polymer beads was decreased by increasing the stirring speed. The bead size was decreased with increasing the degree of polymerization and the concentration of PVA molecules. MMT addition into the monomer portion increased the size of the corresponding polymer beads. The bead size was slightly reduced by adding of styrene to the MMA solution. The incorporation of PMMA into monomer portion enlarged the bead size. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2340–2349, 2005
Positive‐working aqueous base developable photosensitive polybenzoxazole precursor/organoclay nanocomposites
Authors: Hsu Steve Lien‐Chung , Lin Chi‐Yi , Chuang Shih‐Wei 
Published: June 2005

AbstractPositive‐working aqueous base developable photosensitive polybenzoxazole (PBO) precursor/organoclay nanocomposites have been prepared through the addition of an organoclay to a PBO precursor. The organoclay was formed by a cation exchange reaction between a Na+‐montmorillonite clay and an ammonium salt of dodecylamine. The PBO precursor used in this study was a polyhydroxyamide that was prepared from a low‐temperature polymerization of 2′2′‐bis(3‐amino‐4‐hydroxyphenyl) hexafluoropropane and 4,4′‐oxydibenzoyl chloride with an inherent viscosity of 0.3 dL/g. The photosensitive resin/clay formulations were prepared from the precursor with 2,3,4‐tris(1‐oxo‐2‐diazonaphthoquinone‐5‐sulfonyloxy)‐benzophenone photosensitive compound and 3–5 wt % organoclay. The PBO precursor/clay was subsequently thermally cured to PBO/clay at 350°C. Both X‐ray diffraction and transmission electron microscope analyses showed that the organoclay was dispersed in the PBO matrix in a nanometer scale. The thermal expansion coefficient of PBO/clay film, which contained 5 wt % organoclay, was decreased 33% compared to the pure PBO film. The PBO/clay nanocomposite films also displayed higher thermal stability, glass transition temperature, and water resistance than the pure PBO film. The photosensitive PBO precursor/clay nanocomposite showed a line/space pattern with a resolution of 5 μm and its sensitivity and contrast were not affected by the organoclay. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2350–2356, 2005
Synthesis of CdS nanoparticles dispersed within amphiphilic poly(urethane acrylate‐co‐styrene) films
Authors: Kim Ju‐Young , Shin Dong‐Hyun , Ihn Kyo‐Jin 
Published: June 2005

AbstractCdS nanoparticles were prepared using amphiphilic urethane acrylate nonionomer (UAN) precursor chains having a poly(propylene oxide)‐based hydrophobic segment and a hydrophilic poly(ethylene oxide) segment. Cadmium salts were first dissolved in UAN/styrene solutions, and then the solutions were copolymerized to obtain poly(urethane acrylate‐co‐styrene) films containing dissolved cadmium salts. After reduction with H2S gas, freestanding films containing CdS nanoparticles were obtained. Transmission electron microscopy images of the films showed that 9.67‐nm CdS nanoparticles were dispersed within the poly(urethane acrylate‐co‐styrene) matrix. The formation of CdS nanoparticles was also confirmed with UV absorption spectra and photoluminescence emission spectra of the films. Transmission electron microscopy and dynamic mechanical analysis measurements confirmed that hydrophilic/hydrophobic microphase separation in UAN/styrene solutions occurred during the dissociation of the cadmium salts, and the microphase‐separated structures were locked in by crosslinking copolymerization. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2357–2363, 2005
Methacryloylpropyl–βcyclodextrin and vinylpyrrolidone copolymers: Synthesis and characterization as potential chiral selector
Authors: Carbonnier B. , Janus L. , Deratani A. , Morcellet M. 
Published: June 2005

AbstractThe free radical copolymerization of vinylpyrrolidone (VP) with 2‐hydroxy‐3‐methacryloyloxypropyl β‐cyclodextrin (βW7 MAHP), a derivative of hydroxypropyl β‐cyclodextrin (CD) substituted by polymerizable methacryloyl groups, is carried out in water by varying the molar ratio of the comonomers. It is found that the higher the molar ratio of βW7 MAHP to VP, the larger the molar mass of the water‐soluble copolymer. A size exclusion chromatography analysis coupled with multiangle laser light scattering detection (SEC–MALLS) suggests that VP‐rich copolymers with a mass‐average molar mass (MM) of about 2.5 × 104 g mol−1 may consist of βW7 MAHP dimers, trimers, and oligomers containing few CD units whereas βW7 MAHP rich copolymers with an MM of about 5.5 × 106 g mol−1 are likely to be dominated by crosslinked polymer materials. βW7 MAHP‐co‐VP copolymers coated on porous silica are used as high‐performance liquid chromatography chiral selectors. The effects of the structural features of the guest molecule and the characteristics of the chiral stationary phases on the retention and resolution are evaluated. SEC–MALLS detection shows that, by varying the comonomer feed, copolymers with different molar masses and macromolecular structures are formed. The chiral separation ability of Copo VP is evaluated toward enantiomers having one or more aromatic rings as a function of the amount of copolymer adsorbed onto the silica surface, the βW7 MAHP content, and the concentration of solute. It is clear that the column combining the greater amounts of adsorbed copolymer and βW7 MAHP exhibits better resolving power. Moreover, the size, geometry, and functionality of the guest molecule are important factors that strongly affect the enantioselectivity. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2364–2374, 2005
Tensile and flammability properties of polypropylene‐based RTPO/clay nanocomposites for cable insulating material
Authors: Hong Chae Hwan , Lee Yong Bum , Bae Jin Woo , Jho Jae Young , Nam Byeong Uk , Nam Gi Joon , Lee Kun Joo 
Published: June 2005

AbstractNanocomposites of polypropylene‐based RTPO with organically modified clays were prepared by melt compounding of three components, that is, polypropylene‐based RTPO, maleic anhydride‐grafted polypropylene oligomer (PPgMA), and organically modified clay. Their morphologies, tensile behaviors, and flammability properties were investigated. In the clay nanocomposites, the silicate layers were dispersed at the nanometer level, which was confirmed by X‐ray diffraction and transmission electron microscopy. The tensile yield strength of nanocomposites containing 10 wt % clay exhibited 2.8 times higher value compared with that of neat resin. The combustion behavior of the nanocomposites was evaluated by measuring the heat release rate (HRR) using cone calorimetry. The peak HRR was lowered greatly and the char yield was very high compared with those of neat resin. However, these flame retardant properties of clay are not sufficient as a flame retardant used alone in cable applications. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2375–2381, 2005
Graft copolymerization of water‐soluble monomers containing quaternary ammonium group on poly(vinyl alcohol) using ceric ions
Authors: Zheng San‐Yan , Chen Zhi‐Chun , Lu De‐Shui , Wu Qi , Lin Xian‐Fu 
Published: June 2005

AbstractGraft copolymerization of water‐soluble monomers containing quaternary ammonium onto PVA was studied in an aqueous medium using ceric ammonium nitrate‐nitric acid as the redox initiator. To optimize the reaction conditions for obtaining a maximum percent of grafting, the concentrations of methacryloxyethyl trimethylammonium chloride (DMC) monomer, ceric ammonium nitrate, and temperature were varied, and the effects on the grafting copolymerization were discussed. Under optimum conditions, a series of water‐soluble monomers containing quaternary ammonium, such as methacryloxyethyl trimethylammonium chloride (DMC), DMAEMA˙C2H5Br, DMAEMA˙C4H9Br, DMAEMA˙C16H33Br, and DMAEMA˙C7H7Cl, were successfully grafted onto PVA. The resulting grafted PVA were characterized with IR, NMR, and viscosity measurements. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2186–2191, 2005
Effect of low‐temperature plasma and chitosan treatment on wool dyeing with Acid Red 27
Authors: Jocic Dragan , Vílchez Susana , Topalovic Tatjana , Molina Ricardo , Navarro Antonio , Jovancic Petar , Julià Maria Rosa , Erra Pilar 
Published: June 2005

AbstractThis study examines in detail the influence of low‐temperature plasma and biopolymer chitosan treatments on wool dyeability. Wool knitted fabrics were treated and characterized by whiteness and shrink‐resistance measurements. Surface modification was assessed by contact‐angle measurements of human hair fibers, which were used as a model to study the wetting properties of the treated wool knitted fabrics. The dyeing behavior was assessed from the diffusion mechanism point of view. The dyeing kinetics were measured at two different pHs (4.2 and 6.5) and three different temperatures (60, 85, and 100°C) to gain information about the contribution of the surface modification treatment to the dyeing mechanism. The exhaustion and reflectance data were compared, and the apparent diffusion coefficients were calculated. On the basis of the obtained results, a model for the dyeing mechanism of the chitosan treated wool was proposed. When treated with chitosan, the polymer sheath spread on the surface of the fibers acted as a predominant dyeing site in very short dyeing times, thus interacting with the dye and in later stages imparting the dye to the wool fiber. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2204–2214, 2005
Surface photografting polymerization of vinyl acetate, maleic anhydride, and their charge‐transfer complex. IX. Charge‐transfer complex (5)
Authors: Jianping Deng , Wantai Yang 
Published: June 2005

AbstractThe two‐step method was employed to obtain insight into the grafting mechanism of (MAH‐VAC)/LDPE film in the preceding investigation, where photoreduction of BP (the first step) was investigated and the subsequent grafting polymerization (the second step) was studied from the viewpoint of kinetics. The present article is devoted to investigation of the living polymerization performance, the compositions of the grafted chains, and the relevant grafting copolymerization mechanism of the (MAH‐VAC)/LDPE system. Both grafting copolymerization and nongrafting copolymerization performed living polymerization characteristics to some degree. Regarding the nongrafting copolymerization at a monomer concentration, [MAH] = [VAC] = 2M, MAH and VAC mainly underwent alternating copolymerization, especially at low temperatures; however, the grafting copolymerization mostly exhibited random copolymerization, which became obvious with the elevation of temperature. The composition of the monomer feed largely affected the composition of the grafted copolymer and the nongrafted copolymer. When [MAH]/[VAC] was either 2.5/1.5, 2/2, or 1.5/2.5, MAH/VAC in nongrafted copolymers stayed approximately at 1/1; while when [MAH]/[VAC] was 2.5/1.5, MAH/VAC in the grafted copolymer was nearly 1/1; but in the case of [MAH]/[VAC] being 2/2 and 1.5/2.5, the content of MAH in grafted chains was somewhat lower than that of VAC. All these results demonstrated that the grafting copolymerization on the substrate occurred randomly, which was greatly affected by the affinity of the monomer toward the substrate. This performance of the grafting copolymerization was much different from the nongrafting copolymerization in the solution. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2230–2237, 2005
Cure kinetics of T700/BMI prepreg used for advanced thermoset composite
Authors: Guo Zhansheng , Du Shanyi , Zhang Boming , Wu Zhanjun 
Published: June 2005

AbstractA new isothermally based, cure kinetic model for the prepreg was presented using an industrially supplied prepreg rather than pure resin. The matrix resin was bismaleimide (BMI) resins, and the reinforcement was carbon fiber T700–12S. The BMI prepreg was measured from 170 to 220°C by isothermal DSC. The isothermal cure reaction heat increases with the increment of cure temperature. The DSC data were analyzed by the proposed nth‐order reaction model. An increase in reaction rate was observed at higher temperature in both neat and prepreg. After reaching the peak value, the reaction rate dropped off faster in prepreg, resulting in a lower average value of the ultimate heat of reaction. It was suggested the presence of carbon fiber had an effect on the cure kinetics as a heat sink. The carbon fibers imposed restrictions on the molecular mobility of the reactive species and did not change the cure mechanism. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2238–2241, 2005
Diffusion of sulfuric acid solutions in Nylon 6,6 monitored by neutron activation analysis
Authors: Brown L. , Bui V. T. , Bonin H. W. 
Published: June 2005

AbstractNylon 6,6 is an excellent material for the study of the diffusion mechanism and associated mechanical performance of polymers saturated with aqueous solutions of varying pH at different temperatures. The diffusion profile was studied for samples saturated at temperatures ranging from 20 to 90°C in solutions decreasing in pH from distilled water to 1.0M sulfuric acid. The presence of sulfuric acid molecules within the diffusing solutions acts to promote hydrolysis of the polyamide molecules. The degree of hydrolysis is dependent on saturation temperature and solution pH. The extent of degradation was evaluated via changes to mechanical performance and inherent viscosity and often results in a reduction of the stress at yield, flexural modulus, and inherent viscosity on increasing temperature and decreasing pH. The use of neutron activation analysis allowed for an evaluation of the sulfur content within the samples as a function of diffusing time. This demonstrated that although the mechanical performance decreases rapidly on initial exposure to the aqueous medium, this is likely due to plasticization. As diffusion time progresses, the sulfur content within the sample continues to rise to a level where the acid/water molar ratio is much higher in the sample than that of the bulk. This results in an enhancement of the degradation process as time progresses. © 2005 Wiley Periodicals, Inc. J Appl Polym Sci 97: 2476–2487, 2005