bluuebunny/crossref_metadata_2025_split huggingface dataset:
Detecção e tratamento de doença de cushing
Authors: Rocha P. B. , Ferreira J. G. , Barreto M. G. , Porto V. P. S. 
Published: February 2025

Adenomas secretores de ACTH são a causa da doença de Cushing, que representa 70 a 80% dos casos de síndrome de Cushing. A grande maioria (90%) desses tumores é constituída de microadenomas (<1cm) e tradicionalmente têm como tratamento de escolha sua retirada cirúrgica por via transesfenoidal. Relato de caso: M. P. P., 17 anos, menarca aos 13 anos, amenorreia há 9 meses e ganho ponderal há 1 ano, presença de obesidade central, hiperglicemia, hirsutismo, face de lua cheia, presença de estrias violáceas em coxa, axila, tronco, membros inferiores. Sua investigação demonstrou cortisol urinário elevado (1412 μg/24 horas; valor de normalidade em adulto: 10 a 90 μg/24 horas), ACTH normal (11,7 pg/mL, valor de normalidade: 10 - 60 pg/mL) e testes de supressão com dexametasona compatíveis com doença de Cushing. A tomografia computadorizada de adrenais apresentou normalidade e a RMN (ressonância nuclear magnética) de hipófise mostrou microadenoma hipofisário (0,8 cm) que foi encaminhada para o tratamento cirúrgico por via transesfenoidal (TSA). Discussão: Um diagnóstico diferencial preciso do doença de Cushing, de síndrome de Cushing (SC) ou tumores secretores de hormônio adrenocorticotrófico ectópica (ACTH) é um pouco problemático devido a sintomas e sinais comuns. Até recentemente, a amostragem seio petroso inferior (IPSS) com hormônio liberador de corticotropina (CRH) foi realizada para estimular a secreção de ACTH e permitir a discriminação entre doença de Cushing e tumores secretores de ACTH ectópica. A ressecção cirúrgica de um adenoma da hipófise é a terapia de primeira linha para Doença de Cushing, enquanto que a farmacoterapia é uma estratégia de tratamento de segunda linha utilizada para controlar recorrente ou Doença de Cushing sustentada. Embora o cetoconazol, que suprime a síntese de cortisol ao nível da glândula suprarrenal, ser um fármaco eficaz e conveniente usado para controlar o hipercortisolismo, levanta preocupações devido a sua toxicidade hepática. Nas mãos de um cirurgião experiente, essa doença cura potencialmente 100% dos casos. No entanto, implica necessidade de reposição permanente de glicocorticoide e mineralocorticoide, morbidade e mortalidade pós-operatórias potencialmente elevadas, além do considerável risco para o surgimento da síndrome de Nelson. Neste trabalho é descrito um caso de diagnostico de doença de Cushing, causada por microadenoma hipofisário corticotrófico, despertando a atenção dos endocrinologistas clínicos para essa entidade e sugerindo que a investigação laboratorial do hipercortisolismo seja incluída em todos os casos de adenomas hipofisários.
Envelhecimento Populacional
Authors: Costa J. dos S. , Machado L. de C. , Oliveira M. R. de S. 
Published: February 2025

O estereótipo criado sobre a velhice, referente à capacidade e à competência para o trabalho, fez com que fosse taxada como uma fase disfuncional da vida, sendo expressa, por muito tempo, como uma espécie de peso para o desenvolvimento socioeconômico do país. A sociedade sempre se preocupou com a participação dos indivíduos em atividades produtivas, porém não se reorganizou nem se preparou para o envelhecimento populacional. A medicina, por exemplo, concentrou-se, por décadas, no tratamento das doenças em detrimento da prevenção, sem a preocupação devida com a qualidade de vida dos idosos. O perfil deles, no entanto, transformou-se, de forma a quebrar o paradigma criado com o aumento da expectativa de vida e o consequente crescimento da população (cerca de 45,4% só na região do Médio Paraíba, de acordo com os censos de 2000 e 2010) que provocam mudanças nas razões de dependência dela, sendo a estimativa de 66 dependentes para cada 100 pessoas potencialmente produtivas até 2060, segundo o IBGE. A terceira idade passou, então, a participar ativamente da nova organização social, sendo cerca de 1.290.818 idosos como os únicos responsáveis por domicílio, segundo o censo de 2010. Nesse contexto, pode-se observar também, a preferência dos idosos em morar sozinhos, acarretando novas implicações ao Estado, uma vez que cabe a ele garantir seus direitos. Assim, à medida que o país envelhece, faz-se necessário um planejamento dos recursos destinados à garantia dos direitos dos idosos, uma vez que esse fenômeno provoca rearranjo dos recursos destinados a alguns setores, como a saúde pública e a previdência social. A partir dessa constatação, a pesquisa, ainda em andamento, visa quantificar e evidenciar a participação dessa classe na responsabilidade financeira e educacional dos seus lares e no suporte à rotina de trabalho dos filhos. Esta pesquisa objetiva, também, por meio da análise, ratificar as mudanças fundamentais na classe médica, com a criação de políticas de saúde que propõem melhorias na comunicação médicopaciente, na estrutura destinada a eles e na prestação de serviços, indispensáveis ao desenvolvimento da saúde pública do país. Para isso, utilizaremos dados do IBGE e indicadores da ONU, assim como referencias do Estatuto do Idoso.
"Empowering independence: the role of occupational therapy in overcoming life challenges"
Authors: Sadia Saleem  , Khadija Saleem  , Sabeen Masood  , Faiza Yousaf  , Laiba Saleem  
Published: February 2025

Occupational Therapist promote functional independence and achievement of life goals. Occupational Therapy means to make the patient independent in activities of daily living (ADLs) according to patient potential. Occupational therapy practitioners help the patient to participate in daily activities and increase their participation and independence. Occupational therapist help people of all ages to participate in the things they want and need to do through the therapeutic use of everyday activities. In all of their environment home, work, school and community occupational therapist helps people through engagement in occupation that addresses the cognitive, physical and psychological aspects of their well- being. 1
To manage the challenges of delayed milestones, Autism, Attention Deficit Hyperactive Disorder, childhood obesity and other conditions after injury, Occupational Therapist helps children to develop skills in the areas of school, play, and self care. These are seen as child’s main and important areas of occupation. Occupational therapist enable the children to achieve their self esteem, maximum potential, general well being and social skills by supporting the children. 2
Occupational Therapists are instrumental in providing early Intervention for a variety of disorders including Developmental coordination disorder, Developmental delay, Learning difficulties, Dyspraxia, Autistic spectrum disorder, Sensory processing difficulties, Attention deficit hyperactive disorder, Visual perception deficit, in all these disorders occupational therapist work with Handwriting development, Self- care and Social skills, Learning ( develop creativity and imagination through toys and play) . 3
The occupational therapist Addresses following Physical, Developmental & Cognitive Disabilities. 4.

Modifying environments
Providing adaptive equipment
Creating options for play
Addressing social skills
Alleviates sensory challenges.

In Adults, to carry out daily living activities the aim of occupational therapy is to facilitate individuals in the key areas of work, leisure that are meaningful to them. After stroke, surgery or other following medical incidents rehabilitation is provided by occupational therapist to resume function.

Spinal cord injuries
Multiple Sclerosis
Traumatic brain injury
Stroke
Burns

Among older adults, such as dementia enhance well being and overall health and decrease depression and anxiety. Provide rehabilitation and adaptive devices. By providing emotional support and encouragement we minimize the risk of falling by assisting the older adults with balance, posture and safety techniques.
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RANCANGAN BANGUN MESIN KOMBINASI CORN SHELER BIJI JAGUNG DAN COUNTER TONGKOL JAGUNG
Authors: Jamaluddin Jamaluddin , M Saripuddin , Trumiabi Rizal , Yamin Nur Habibi 
Published: February 2025

Proses pemipilan jagung dan pencacahan tongkol sebagian besar dilakukan dengan tangan secara manual, jadi butuh waktu lama untuk bekerja dalam pemipilan dan pencacahan. Tujuan dari penilitian melakukan proses rancang bangun mesin kombinasi Corn Sheller biji jagung dan counter tongkol jagung dan melakukan pengujian mesin kombinasi Corn Sheller biji jagung dan counter tongkol jagung. Metode yang digunakan meliputi pengumpulan data melalui studi pustaka, analisa data mengenai waktu yang diperoleh dalam proses pemipilan dan penacahan, tingkat efektifitas dan ketidak efektifan alat, perhitungan perancangan perbandingan alat dengan sistem tenaga manual dan perbandingan dengan alat yang sudah. Prosedur penelitian dilakukan melalui tahap perencanaan unutk menentukan alat, bahan dan desain, tahap pelaksanaan unutk proses kerja lapangan, tahap uji coba untuk mengaplikasikan alat, penyusunan uji cooba penerapan instrumen. Hasil yang didapat dari peracangan adalah dalam kerangka alat mesin kombinasi Corn Sheller biji jagung dan counter tongkol jagung yang mempunyai ukuran panjang 120 cm, tinggi 93 cm, lebar 50 cm daan memiliiki sebelas kompoonen deengan kontrol motor yaang dibuat seluas 3600 rpm . Hasil dari pelaksanaan alat tersebut mendapatkan tingkat efisiensi pemipilan jagung 95% sedangkan tingkat efesiensi pencacahan tongkol 93%, kerugiann produktifitas pemipilan jagung 5% dan kerugian produktifitas pencacan tongkol 5% waktu rata-rata yang dihasilkan adalah 47 detik dan 54 detik. Kesimpulan dari penilitian ini yakni perancangan dan pembuatan mesin kombinasi corn sheller biji jagung dan counter tongkol yang mampu melakukan proses penipilan dan pencacahan sebanyak 2 kg jagung selama 47 detik untuk pemipilan jagung 54 detik untuk pencacahan tongkol. Bahwa mesin kombinasi corn sheller biji jagung dan counter tongkol jagung dengan kapasitas pemipil jagung yang di hasilkan 440 kg/jam dan kapasitas pencacah tongkol jagung yang di hasilkan 370 kg/jam.
Rancang Bangun Alat Pengering Rumput Laut Menggunakan Solar Sel
Authors: Manguluang Zulkifli , Rahman Fadhli , Mappatoba Andi , Ashari Muh. 
Published: February 2025

Proses pengeringan rumput laut terdapat beberapa kendala yang membuat produksinya lambat salah satu proses pengeringan memakan waktu yang lama dan mengganggu masyarakat sekitar disebebkan bau dari rumput laut. Tujuan penelitian adalah merancang dan menguji alat pengering rumput laut menggunakan solar sel untuk mempermudah dan mengatasi keluhan pada masyarakat. Metode penelitian ini menggunakanj jenis kualitatif dengan metode eksperimental rancang bangun alat yang menghitung arus yang merambat pada termal serta terdiri dari beberapa tahap yaitu analisis perancangan, desain alat, membuat alat, pengujian alat. Hasil rancang alat pengering rumput laut ini sangat baik digunakan pasalnya proses pengeringan sangat cepat yang hanya membutuhkan 4 jam selama 3 kali percobaan, ini disebabkan sedikitnya ruang ventilasi serta suhu 63oc dan kelembaban 62% yang sudah ditetapakan, maka hasil dari jam pertama 1,4 kal, 2 jam 0,7 kal, dan 3 jam 0,4 kalor yang merambat dan rumput laut sudah nampak kering. Kesimpulan dari perancangan alat tersebut bahwa alat pengering rumput laut menggunakan solar sel dapat berfungsi dengan baik dan dilakukan pengujian 3 kali.
Об особенностях экономической безопасности деятельности учреждений уголовно-исполнительной системы как объекта мониторинга
Authors: Соколов А.П. , Носов А.А. 
Published: February 2025

В статье рассматривается специфика экономической безопасности в деятельности пенитенциарных учреждений как объекта мониторинга. Анализируются подходы к оценке экономической безопасности в этих учреждениях, выявляются ключевые риски и угрозы, а также их влияние на стабильность системы. Особое внимание уделено законодательным и методологическим аспектам обеспечения экономической безопасности в Российской Федерации, а также изучению международного опыта в данной области. Предложены рекомендации по повышению экономической безопасности исправительных учреждений, включая совершенствование нормативно-правовой базы и инструментов управления. Подчеркивается необходимость системного подхода к мониторингу и разработке эффективных мер на основе полученных данных.
The article examines the specifics of economic security in the activities of penitentiary institutions as an object of monitoring. The approaches to assessing economic security in these institutions are analyzed, key risks and threats are identified, as well as their impact on the stability of the system. Special attention is paid to the legislative and methodological aspects of ensuring economic security in the Russian Federation, as well as to the study of international experience in this field. Recommendations are proposed for improving the economic security of correctional institutions, including improving the regulatory framework and management tools. The need for a systematic approach to monitoring and the development of effective measures based on the data obtained is emphasized.
Implementación de las curvas de densidad electrónica relativa al sistema de planificación de tratamiento en teleterapia mediante la calibración estequiométrica
Authors: Guzman Calcina Carmen Sandra , Pinedo Cadillo Richar Ricardo , Picón Chávez Cesar , Méndez Velásquez Juan Abraham , Villaverde Herrera Jessenia Brillit 
Published: February 2025

Objetivos: El objetivo de este trabajo fue integrar curvas de densidad electrónica relativa al sistema de planificación de tratamiento CAT3D utilizando el método alternativo de la calibración estequiométrica.
Métodos: Se utilizó aluminio como material de calibración y un maniquí torácico con insertos y se consideraron 3 casos en la planificación del tratamiento: campo directo 10x10cm2, campo directo 20x20cm2 y campo lateral 10x10cm2 con cuña, donde se puso a prueba el sistema de planificación basado en el algoritmo Pencil Beam
Resultados: Se encontró que el uso incorrecto de estas curvas afecta significativamente la dosis absorbida hasta en un 6% en regiones de cambios bruscos de densidad, excediendo la tolerancia recomendada de ±5% en la entrega de dosis adsorbida en regiones de equilibrio electrónico.
Conclusiones: Se concluyó que la implementación y uso correcto de estas curvas mejora la aproximación en medios heterogéneos, reduciendo la desviación de sus resultados
Prevalence of Gastro-Intestinal Parasitic Infestation in Cows with Various Reproductive Ailments in Tribal Areas of Himachal Pradesh
Authors: Sharma Ankita , Singh Madhumeet , Kumar Pravesh 
Published: February 2025

Gastrointestinal (GI) parasitic infection poses a significant concern in cattle management. The influence of gastrointestinal (GI) parasites on reproduction is contingent on multiple factors. Faecal samples were collected from 285 reproductively compromised, normal cyclic and pregnant cattle from five different tribal zones of Himachal Pradesh viz. Lahaul, Spiti, Kinnaur, Pangi and Bharmour. Coprological examination revealed the presence of gastro-intestinal parasites in 47 percent of cattle whereas 52.9 percent cattle were bereft of it. Incidence of gastro-intestinal parasites was highest (15.7%) in true anestrus cows followed by endometritis (12.2%), pregnant cattle (9.4%), silent estrus (6.3%), miscellaneous (2.1%), and normal cyclic (1.05%), respectively. Overall incidence of different parasites i.e., strongyles, oocyst of protozoans (Coccidia), amphistomes, cestodes (Moneizia spp.) and mixed infestation was 25.61, 5.61, 2.45, 0.3 and 12.98 percent, respectively. Among the different physiological and pathological conditions, anestrus cows had the highest incidence (22%) for parasitic load.
Dystocia Due to Incomplete Cervical Dilatation and Breech Presentation of Fetus in a Goat
Authors: Sharma Renu , Gupta Shashikant , Das Goutam Kumar , Ghosh Subrata Kumar 
Published: February 2025

In the Referral Veterinary Polyclinic, ICAR-Indian Veterinary Research Institute, Bareilly, a case report of a pregnant doe aged 2 years old who was unable to deliver the fetus was presented. Due to insufficient cervical dilation, doe was unable to deliver the fetus, resulting in dystocia. Induction treatment was done along with CMC massaging of cervix for 10 minutes after every 30 minutes. After 2 hours of this therapy the cervix was fully dilated and the appearance of water bags was observed. Then per vaginal examination was done and fetus were observed in posterior presentation which were delivered by traction. Both live fetuses were having myxoedema and one fetus was without hairs which is characteristic of congenital goiter in kids. This case report describes an instance of dystocia in a goat caused by ICD and due to breech presentation of fetuses. The fetuses were delivered successfully.
Extrinsic and intrinsic strength of amorphous olivine films
Authors: Jarnot Jens , Dohmen Ralf , Trost Claus O. W. , Mitterer Christian , Cordier Patrick , Glushko Oleksandr 
Published: February 2025

Abstract. Nanoscale amorphous olivine (a-olivine) intracrystalline layers, which can form in olivine polycrystals under high stress, has the potential to influence the mechanical properties of the rock in the vicinity of the brittle–ductile transition. It is therefore essential to determine the mechanical properties, in particular the strength, of these a-olivine films. To this end, we investigate the tensile deformation and fracture of a-olivine thin films deposited on a polymer substrate. Typical brittle fracture in the form of numerous long, straight cracks that are parallel to each other is observed during a tensile test. Using in situ measurements of electrical resistance, the critical strain required for the generation of the first cracks was measured at 0.8 %. A combination of in situ straining with optical microscopy and subsequent digital image correlation enables direct measurements of local strains within the unfractured film regions. It is demonstrated that a-olivine can withstand tensile strains of at least 2 %, which leads to an estimated intrinsic strength of 1.8 GPa. The results presented should contribute to a more comprehensive understanding of the mechanical behavior of olivine-rich rocks affected by grain boundary amorphization.
« L’écriture a indéniablement un caractère politique » : entretien avec Gabrielle Giasson-Dulude sur son essai-création Entre les murs, des voix
Authors: Ngamaleu Armel Jovensel 
Published: February 2025

Entre les murs, des voix est un essai-création issu de la thèse de doctorat de Gabrielle Giasson-Dulude. Dans cet entretien, l’essayiste aborde les questions du rapport du sujet écrivant au contexte d’écriture et à la forme textuelle ou la poétique à l’œuvre et à l’épreuve. Giasson-Dulude conçoit l’acte d’écrire comme une performance sous-tendue par la volonté d’investir les marges, de conquérir la liberté pour soi, ainsi que pour les autres avec qui on est (in)directement en relation et partage au quotidien des schèmes de vulnérabilité. Son essai engageant, résolument politique, s’inscrit dans une dynamique d’attention, « d’intervention » et de réparation des violences sociales et individuelles.
« L’indépendance du Québec fera des miracles. » Entretien avec Maxime Blanchard
Authors: Ngamaleu Armel Jovensel 
Published: February 2025

Cet entretien fait suite au précédent qui a porté sur Le Québec n’existe pas. Il se caractérise par le style subtilement incisif et performatif de Maxime Blanchard. La mère patrie est le second volet de son projet trilogique pro indépendantiste du Québec. L’essayiste dans ses deux premiers essais mordants performe, à travers une rhétorique politique et sociologique, une écriture-programme qui autopsie l’époque contemporaine en général et dessine le rêve d’un Québec indépendant, en particulier.
« Je pense qu’il n’y a pas plus politique que la littérature » : poésie et politique ou politique de la poésie chez Michel Feugain (entretien)
Authors: Ngamaleu Armel Jovensel 
Published: February 2025

Michel Feugain est poète, traducteur, éditeur et universitaire français d’origine camerounaise. Il écrit à travers sa poésie-satire la chronique chaotique de sa patrie en léthargie, plongée dans une ère d’incertitude. Thrènes de l’entre-deux, comme ses précédents livres, est un tableau sombre et choquant de la déchéance politique, sociale et morale du pays natal de Feugain. Il y fait le procès de l’État depuis son indépendance en le considérant comme principal responsable des malheurs de ses concitoyens. Le poète se veut ainsi le témoin, la voix des sans voix et le visage des invisibles, des victimes vivantes ou mortes, oubliées ou dans l’ombre. Cet entretien, à l’image du recueil très caustique, constitue un si « long et grand cri » d’un poète révolté, pugnace et optimiste pour qui « la pensée littéraire est un chemin qui éclaire la conscience du politique ».
1 Kings 2:1–9, the So-called Installation Genre, and Egyptian Royal Instruction
Authors: Schreiner David 
Published: February 2025

Abstract
This article considers D. J. McCarthy’s proposed installation genre and Egyptian instruction texts as interpretive frameworks for 1 Kgs 2:1–9. After examining the salient features of McCarthy’s proposal, this article considers the degree to which his biblical argument enjoys comparative support as many commentators invoke his proposed genre alongside Egyptian instruction texts to explain 1 Kgs 2:1–9. Egyptian royal instruction texts, such as the Instruction to Merikare and the Instruction of Amenemhet, display a concern for a king’s instruction to his successor. It is determined that while the literary relationship between McCarthy’s proposed installation genre and Egyptian instruction, or even royal instruction, requires further study, Merikare and Amenemhet clarify important poetic and functional features of 1 Kgs 2:1–9. In particular, the biblical text shares a concern for ideologically inspired exhortations as well as actions stimulated by the outgoing king’s historical reflections. The juxtaposition of practical exhortation with a set of reflections stemming from the king’s personal history evident in the Egyptian texts clarify what has traditionally been understood as an awkward, even a morally compromising, apposition. Ultimately, 1 Kgs 2:1–9 can be better understood as an Israelite example of royal instruction.
QALAMPIRMUNCHOQ (SYZYGIUM AROMATICUM L.) TARKIBIDAGI POLIFENOLLAR MIQDORINI ANIQLASH
Authors: Mo'minjonov Mirjalol Muqimjon o'g'li , Aliqulova Irodaxon Maxmudovna 
Published: February 2025

Ushbu maqolada dorivor qalampirmunchoq (Syzygium aromaticum L.) o’simligining botanik tavsifi, umumiy kimyoviy tarkibi o’rganildi. Dorivor qalampirmunchoq (Syzygium aromaticum L.) o’simligi tarkibidagi polifenollar miqdorini yuqori samarali suyuqlik xromatografiyasi usulida aniqlash natijalari keltirildi. Hamda xalq tabobatida polifenollar ko’z kasalliklaridan ko’z yallig’lanishini oldini olish xususiyatlari xaqida yoritib berildi.