bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mediation and Dose-Response Relationship Among Physical Activity, Daylight Exposure, and Rest-Activity Circadian Rhythm in Patients With Esophageal and Gastric Cancer
Authors: Chen Hui-Mei , Cheung Denise Shuk Ting , Huang Chien-Sheng , Wu Yu-Chung , Hsu Po-Kuei 
Published: November 2023

Background
Physical activity and daylight exposure predict rest-activity circadian rhythm (RACR) in patients with cancer. However, whether daylight exposure mediates the relationship between physical activity and RACR and the optimal amounts of physical activity and daylight that benefit RACR remain unclear.

Objectives
This study investigated the mediating role of daylight exposure and determined the dose-response relationship among daylight exposure, physical activity, and RACR in patients with cancer.

Methods
This cross-sectional exploratory study recruited 319 patients with esophageal and gastric cancer from 2 surgery outpatient departments in Taiwan. Daylight exposure (>500 lux), physical activity (up activity mean), and RACR (midline estimating statistic of rhythm) were measured through actigraphy. Regression was performed, and the receiver operating characteristic curve was plotted.

Results
Daylight exposure (>500 lux) partially mediated the relationship between physical activity (up activity mean) and RACR (midline estimating statistic of rhythm). The optimal cutoffs for discriminating between satisfactory and poor RACR were 187.43 counts/min for physical activity (sensitivity, 90.3%; specificity, 84.4%) and 35.71 min/d for daylight exposure (sensitivity, 55.9%; specificity, 78.2%).

Conclusions
Participants who engaged in physical activity were more likely to receive daylight exposure and experience improved RACR. The optimal level of daylight exposure and frequency of physical activity that can improve RACR in patients with esophageal and gastric cancer are 36 min/d and 187 counts/min, respectively.

Implications for Practice
Healthcare professionals should encourage patients to engage in exercise or physical activity during the daytime to improve their circadian rhythm.
Identification of the host reservoir of SARS-CoV-2 and determining when it spilled over into humans
Authors: Pamjula Vidyavathi , Strachan Norval J.C , Perez-Reche Francisco J. 
Published: November 2023

1AbstractSince the emergence of SARS-CoV-2 in Wuhan in 2019 its host reservoir has not been established. Phylogenetic analysis was performed on whole genome sequences (WGS) of 71 coronaviruses and a Breda virus. A subset comprising two SARS-CoV-2 Wuhan viruses and 8 of the most closely related coronavirus sequences were used for host reservoir analysis using Bayesian Evolutionary Analysis Sampling Trees (BEAST). Within these genomes, 20 core genome fragments were combined into 2 groups each with similar clock rates (5.9×10−3and 1.1×10−3subs/site/year). Pooling the results from these fragment groups yielded a most recent common ancestor (MRCA) shared between SARS-COV-2 and the bat isolate RaTG13 around 2007 (95% HPD: 2003, 2011). Further, the host of the MRCA was most likely a bat (probability 0.64 - 0.87). Hence, the spillover into humans must have occurred at some point between 2007 and 2019 and bats may have been the most likely host reservoir.
Biosurfactant stabilized nanoemulsions as multifunctional magnetically targeted delivery vehicles
Authors: Wilson Russell J. , Liu Yun , Yang Guangze , Gao Yuan , Zhao Chun-Xia 
Published: November 2023

AbstractNanoemulsions have been widely used for pharmaceutic applications. However, there remains a significant challenge to functionalize available pharmaceutical surfactants with targeting or reporter moieties to generate next-generation drug delivery systems. Herein, a designed biosurfactant platform technology, based on our library of α-helical peptide AM1 derivatives, was used to prepare multifunctional magnetic nanoemulsion drug delivery systems. Key factors such as electrostatic and steric stabilization of the nanoemulsions were determined using this peptide library. Stabilization of the nanoemulsion was achieved by controlled and tunable loading of PEG-functionalized biosurfactant at the oil-water interface. A model drug and iron oxide nanoparticles were incorporated into the oil core to prepare multifunctional nanoemulsions.In vitrocell uptake experiments using an external magnetic field demonstrated controlled rapid uptake of iron oxide loaded nanoemulsions by SKOV3 cancer and RAW 264.7 macrophage cells. SKOV3 cells demonstrated a slower rate of uptake under a magnetic field when compared to RAW 264.7 cells. This work demonstrates a highly adaptable hierarchical nanoemulsion system that can provide a platform to develop effective multifunctional nanomedicines and tools for biomedical insights.Graphical Abstract
Islamic governance and leverage: the interacting role of corporate social responsibility disclosure
Authors: Puspitasari Novi , Harymawan Iman , Ab Aziz Norazlin 
Published: November 2023

Purpose
This study aims to analyze the relationship between Islamic governance (IG) and leverage and examine the interaction of corporate social responsibility disclosure (CSRD) in the relationship between IG and leverage.

Design/methodology/approach
This study used 444 observational data comprising Asian, European and African Islamic banks (IBs) and analyzed using the regression analysis method to answer the research hypothesis.

Findings
This study finds that IG had a significant positive effect on leverage, indicating that it can increase the leverage of IBs. In other words, IG boosts the public confidence to entrust their funds to IBs through current accounts and savings. However, this study shows that CSRD weakens the relationship between IG and leverage. In addition, this study includes the control variables of board size, Islamic supervisory board size and company size, where all three variables showed their effect on leverage. These results were obtained through additional analysis by categorizing our sample based on CSRD.

Research limitations/implications
The results of this study show that IG significantly positively affects IB leverage globally. This can be used as a basis for policymakers to include the ICG variable in analyzing IBs leverage. The weakness of this study is the use of IG variables based on disclosure so that IG components that affect leverage cannot be analyzed accurately. Future research can use the IG variable by using specific IG component values such as the number of meetings, member attendance and remuneration of SSB members in analyzing IB leverage globally.

Originality/value
To the best of the authors’ knowledge, this research is the first study to discuss the interaction of CSRD with IG on leverage in Islamic banking in Asia, Europe and Africa, thus adding to the existing literature on Islamic banking.
Prioritisation and causal relationships of industry 4.0 readiness determinants: empirical validation of an assessment framework
Authors: Samaranayake Premaratne , Ramanathan Krishnamurthy , Weerabahu Weerabahu Mudiyanselage Samanthi Kumari 
Published: November 2023

PurposeThe main purpose of this research is to (1) prioritise key determinants of Industry 4.0 (I4.0) readiness assessment and (2) evaluate causal relationships among those determinants and associated sub-criteria based on inputs from industry experts.Design/methodology/approachThe methodology involved two phases: (1) an MCDM approach for determining causal relationships among determinants and (2) empirical validation of findings from the first phase using industry experts' inputs.FindingsIt was found that while the choice of I4.0 technologies is important, organisational factors are also critical, as evidenced by the ranking of the “Strategy and Organisation” determinant as the highest rank prominent determinant. Also, the ranking of the sub-criteria within each determinant shows the importance of several organisational influencing and resulting sub-criteria.Research limitations/implicationsThis research extends the existing literature on I4.0 by demonstrating the prioritisation of determinants and delineating causal relationships among them and associated sub-criteria as a basis for developing I4.0 adoption guidelines. This research is limited to the specific scope of determinants selected/considered and experts' inputs from the Sri Lankan manufacturing sector. Future studies could consider extending this research into a broader global manufacturing context.Practical implicationsPrioritisation and causal relationships of I4.0 readiness assessment determinants, supported with inputs from functional managers and industry experts, could be used to guide practitioners in developing guidelines for I4.0 adoption in a phased manner.Originality/valueThis research provides a re-evaluation and validation of a selected I4.0 readiness assessment framework from the perspectives of interdependencies and casual relationships among its determinants and sub-criteria, based on inputs from industry experts as a basis for developing guidelines for I4.0 adoption.
Pakistan’s export potential assessment at intensive and extensive margins
Authors: Ahmad Imtiaz , Ahmad Maha , Qadir Ghulam , Afridi Asad Khan 
Published: November 2023

Purpose
This study aims to estimate Pakistan’s export potential in new and existing export products, as well as their potential destination markets.

Design/methodology/approach
This study uses a nonparametric approach based on demand, supply and easiness factors for estimating export potential at disaggregated product and destination levels.

Findings
A significant number of new export products (extensive margin) and existing products (intensive margin) are identified that have export potential. The estimated unrealized export potential at extensive margins is $2bn and at intensive margins is $5bn. The range of new products included value-added products, semifinished products and intermediate products. Surprisingly, there is high potential to diversify in China and export existing products more intensively in the EU. Moreover, the potential at extensive margins is regional diverse compared to intensive margins.

Research limitations/implications
The methodology used in this paper only provides export potential for short-to-medium term period because the global demand conditions are varying. Also, the mineral and resource-based products cannot be included in the analysis because their exports are heavily dependent on the availability of natural resources.

Practical implications
The findings have important policy implications in terms of providing guidelines for government policies related to industrial development, international trade and export promotion at the product and destination level. Overall, the study reveals that traditional sectors lack room for product diversification. As the existing export incentives favor major industries. To foster diversification, existing incentives must be redesigned to cover new products or sectors. Moreover, China has the greatest potential for product diversification, while Europe has the greatest potential to export current products more intensively. Further research is needed to simulate trade policy scenarios and estimate demand, supply and ease factors in export potential.

Originality/value
This study provides a unique perspective on export potential assessment at disaggregated product and destination levels, reinforcing the importance of redesigning trade policies and export incentives separately for export diversification.
Dismantling structural and individual cisgenderism in Illinois libraries: a descriptive research study on cisnormativity, transprejudice and biases against transgender and nonbinary populations
Authors: Ness Cristalan 
Published: November 2023

PurposeRecent library and information science literature suggests transgender and nonbinary populations are not treated, served and represented on an equal or equitable basis as cisgender populations are in libraries. This article aims to assess the prevalence of bias and inclusion efforts in Illinois libraries.Design/methodology/approachThis quantitative, cross-sectional, descriptive study utilizes a critical queer theory lens and includes a Likert scale survey with a demographic question on gender identity to measure four constructs and determine if there is a relationship between gender identity and bias, inclusion efforts, and knowledge of transgender and nonbinary user needs.FindingsResults suggest respondents' biases reinforce structural cisgenderism in Illinois libraries and may account for the unequal conditions trans and nonbinary populations experience. Additionally, there is a correlation between cisgender-identifying Illinois LIS professionals and biased attitudes and behaviors, use of inclusive practices, and knowledge of transgender and nonbinary user needs.Originality/valueThis study contributes quantitative data, analysis and practical implications to a body of predominantly qualitative library literature on transgender and gender diverse experiences in libraries.
Exploring an automated method for the analysis of virtual reference interactions
Authors: Turp Clara , Hervieux Sandy 
Published: November 2023

PurposeThis study aims to determine if automated coding with regular expression is a strong methodology to identify themes in virtual reference chat.Design/methodology/approachThe authors used a combination of manual and automated coding of chat transcripts for a period of two years to identify the categories of questions related to the new library system. This methodology enabled them to determine if regular expression accurately identified the topics of chat transcripts.FindingsThey discovered that regular expression is an appropriate method to identify themes in virtual reference interactions. This method enabled them to establish that patrons asked questions related to system changes in the weeks following their implementations.Originality/valueThis study highlights a new methodology for transcript analysis.
The art museum as activist: A case study
Authors: Gullickson Charis 
Published: November 2023

AbstractHow do art museums illuminate patriarchal ideologies for the general public? In this article I share my experiences with critical pedagogies developed for the exhibition Like Betzy (2019–2020) by Nordnorsk Kunstmuseum (Northern Norway Art Museum). The art museum intervened in its exhibition and monuments in public spaces to attract engagement with local communities, critically question, and instigate dialogue and debate on the persistence of gender inequality. Using institutional critique as a theoretical and methodological framework, this analysis demonstrates a case of art museum activism. Additionally, I address the implications of transgression in the art museum's normative modus operandi. Although this case study is specific to a local context, I argue that monuments can serve as a site for public vulnerability, a place where museums step beyond their walls and outside their echo chambers to incite positive social justice‐oriented changes in communities.
Saving the Vietnamese Mekong River Delta—People's attitudes, opinions and willingness to help
Authors: Ahlheim Michael , Vuong Duy Thanh 
Published: November 2023

AbstractThe unique nature and environment of the Vietnamese Mekong Delta as well as its agricultural production and its traditional lifestyle are endangered by a rising sea level and increasing salinization of the ground and surface water. This paper aims at the assessment of Vietnamese people's information on and attitudes towards these problems as well as their respective convictions and beliefs. Imbedded in an online survey with 2000 completed interviews we also conducted a Contingent Valuation study with which we want to assess people's willingness to contribute personally and financially to saving the Mekong Delta as an indication of the benefits they would expect from such a project. We interviewed three different groups of respondents, one of which lives directly in the Mekong Delta, a second lives outside the Delta, but close to it, that is in Ho Chi Minh City, and the third group lives far away from the Delta in Hanoi. With these three subsamples of respondents we wanted to capture not only the use benefits but also the nonuse benefits accruing from such a project. In the course of the interviews, we found that the Mekong Delta is of great interest and importance to all interviewees, no matter in which part of Vietnam they live. They were mostly well informed on the problems there and had strong opinions on the causes of these problems as well as on suitable strategies to fight them. In our Contingent Valuation study, we assessed the willingness of people at the different study sites to contribute financially to a hypothetical project for the preservation of the Mekong Delta and the socio‐economic, attitudinal and psychological determinants of this willingness. Besides these empirical findings, we also obtained valuable insights regarding various methodological aspects of Contingent Valuation studies.
Can't pass or won't pass: the importance of motivation when quantifying improved connectivity for riverine brown trout Salmo trutta
Authors: Dodd Jamie R. , Cowx Ian G. , Joyce Domino A. , Bolland Jonathan D. 
Published: November 2023

AbstractReversing the negative impacts that anthropogenic habitat fragmentation has on animal movement is a key goal in the management of landscapes and conservation of species globally. Accurate assessment of measures to remediate habitat fragmentation, such as fish passage solutions in rivers, are imperative but are particularly challenging for territorial species, which are less likely to leave their existing home range, or populations composed of both migratory and resident individuals (i.e., partial migration). This investigation quantified the movements of translocated (captured upstream of the impediment and released downstream) and non‐translocated (captured and released downstream of the impediment) riverine brown trout (Salmo trutta L.), a species known to perform a homing movement, through a fish pass using passive integrated transponder (PIT) telemetry. A significantly higher proportion of translocated fish approached, entered, and passed (on a wider range of flows) compared to non‐translocated fish, consistent with the theory that motivation is a key driver in fish pass use. Translocated fish that entered the pass were significantly larger than those that approached but did not enter, presumably due to physiological capability. Translocated fish were a more reliable indicator of the fish passage solution effectiveness than non‐translocated fish. Our findings hence imply that many fish passage solutions globally, and potentially measures to remediate habitat fragmentation for other taxa, may have been mistakenly assessed for unmotivated animals. Studying both non‐translocated and translocated fish is recommended to provide more accurate and cost‐effective fish passage solution assessments.
Genetic mechanisms and biological processes underlying host response to ophidiomycosis (snake fungal disease) inferred from tissue‐specific transcriptome analyses
Authors: Mathur Samarth , Haynes Ellen , Allender Matthew C. , Gibbs H. Lisle 
Published: November 2023

AbstractEmerging infectious diseases in wildlife species caused by pathogenic fungi are of growing concern, yet crucial knowledge gaps remain for diseases with potentially large impacts. For example, there is detailed knowledge about host pathology and mechanisms underlying response for chytridiomycosis in amphibians and white‐nose syndrome in bats, but such information is lacking for other more recently described fungal infections. One such disease is ophidiomycosis, caused by the fungus Ophidiomyces ophidiicola, which has been identified in many species of snakes, yet the biological mechanisms and molecular changes occurring during infection are unknown. To gain this information, we performed a controlled experimental infection in captive Prairie rattlesnakes (Crotalus viridis) with O. ophidiicola at two different temperatures: 20 and 26°C. We then compared liver, kidney, and skin transcriptomes to assess tissue‐specific genetic responses to O. ophidiicola infection. Given previous histopathological studies and the fact that snakes are ectotherms, we expected highest fungal activity on skin and a significant impact of temperature on host response. Although we found fungal activity to be localized on skin, most of the differential gene expression occurred in internal tissues. Infected snakes at the lower temperature had the highest host mortality whereas two‐thirds of the infected snakes at the higher temperature survived. Our results suggest that ophidiomycosis is likely a systemic disease with long‐term effects on host response. Our analysis also identified candidate protein coding genes that are potentially involved in host response, providing genetic tools for studies of host response to ophidiomycosis in natural populations.
Caregiving for frail home‐dwelling older people: A qualitative study of family caregivers' experiences
Authors: Søvde Bente Egge , Sandvoll Anne Marie , Natvik Eli , Drageset Jorunn 
Published: November 2023

AbstractBackgroundThe increasing frailty of home‐dwelling older people can lead to rising expectations from their family caregivers due to various demographic developments and political guidelines. European data show that 60% of home‐dwelling older people receive informal care. Frailty among older people is a state of vulnerability, increasing the risk of adverse health outcomes, declining daily activities and needing long‐term care.AimTo explore family caregivers' lived experiences with caring for frail, home‐dwelling older people.MethodsWe conducted a phenomenological study to obtain in‐depth descriptions of the phenomenon. We interviewed nine family caregivers, five men and four women between 52 and 90 years old, in‐depth in their homes. We used a hermeneutical phenomenological approach described by van Manen and followed the COREQ checklist.ResultsThe phenomenon's essential meaning is described as striving to adapt throughout the caring relationship. The interrelated themes describe different caring relationships, caring for a family member and letting go of the primary caring responsibility.ConclusionsFamily caregivers describe care as meaningful yet demanding. In our study, the varying condition of frailty was an additional challenge in care. By addressing these challenges, healthcare providers can better support and help family caregivers to withstand their caring relationships. The Norwegian Centre for Research Data approved the study (Ref.61202).