bluuebunny/crossref_metadata_2025_split huggingface dataset:
Aspirin and poetry: Did João Cabral de Melo Neto suffer from acetylsalicylic acid-overuse headache?
Authors: Cardoso Milena , Meneses Neto Pedro , Silva-Néto Raimundo Pereira 
Published: January 2024

Introduction
João Cabral de Melo Neto is considered one of the most important Brazilian poets of all time. He suffered from severe headaches for the longest part of his life, being diagnosed with migraine. He took a significant amount of acetylsalicylic acid pills every day for many years.
Objective
The objective of this narrative review includes identifying how headache and its treatment influenced João Cabral de Melo Neto's poetry as well as analyzing the correlation between Melo Neto's migraine diagnosis and his documented overuse of aspirin and investigating the possibility of an acetylsalicylic acid-overuse headache diagnosis.
Methods
The authors thoroughly read biographical books and interviews about the life of João Cabral de Melo Neto. They systematically documented all references to headaches and aspirin. Melo Neto's clinical case documented in his biography and interviews were juxtaposed with The International Classification of Headache Disorders (ICHD-3) diagnostic criteria for acetylsalicylic acid-overuse headache diagnosis.
Results
The word “aspirin” appears 8 times in 6 of Melo Neto’s poems. He compares it to the sun, attributing to it the capacity to refocus a "blurred body" (his state during a headache). The poet reported that took one aspirin pill every hour every day, for several years.
Conclusions
Headache and the use of acetylsalicylic acid influenced João Cabral de Melo Neto’s poetry and life. He presented a risk behavior for developing medication overuse headache, specifically its subform: acetylsalicylic acid-overuse headache.
The Prevalence of migraine and associated factors among medical students in Ouagadougou (Burkina Faso)
Authors: Dabilgou Alfred Anselme , Dravé Alassane , Kyelem Julie Marie Adeline Wendlamita , Doukouré Mahamoudou Lamine , Napon Christian , Millogo Athanase , Karfo Kapouné , Kaboré Jean 
Published: January 2024

Objective:
To determine the prevalence, clinical characteristics and impact of migraine among medical students in the city of Ouagadougou.
Methods:
This across-sectional study was carried out during a period of 6 months from August 2021 to January 2022. Participants were selected by stratified random sampling according to academic level. Hetero-administered questionnaire was administred to each student. Migraine was diagnosed according to the ICHD 3rd edition criteria and the MIDAS was used to assess the impact of migraine on students' quality of life.
Results:
Two hundred and twenty seven students were selected for this study. The prevalence of migraineurs was 31.8%. Their mean age was 22.20±2.67 years. There was female predominance among the migraineurs (73.9%). More than half of the migraineurs had a family history of headache disorders (53.6%). Migraine without aura was the most frequent subtype (59.4%). Visual aura was predominant (78.2%). Migraine was of moderate intensity in 60.8% of cases. Insomnia and/or lack of sleep was the most common trigger (73.7%) followed by stress and fatigue in 71% of cases. Migraine caused severe disability in 15.9% of migraineurs.
Conclusion:
There was a high prevalence of migraine among medical students in Burkina Faso. Stress and irregular sleep were the most common triggers factors.
Key words: prevalence, impact, migraine, medical student, Burkina Faso
Migraine Preventive Treatment Failure: A Cross-Sectional Study in a Tertiary Center in Brazil
Authors: Oliveira Arão Belitardo , Nogueira Eduardo Almeida Guimarães , Peres Mario Fernando Prieto 
Published: January 2024

BackgroundIn Brazil, there is a scarcity of evidence on migraine burden in patients who have experienced previous preventive treatment failure (PPTF). ObjectiveTo evaluate the associations between ≥ 3 PPTF and clinical, psychiatric, and medical history data.MethodsIn a retrospective, cross-sectional study, the medical records of migraine patients who first visited a tertiary specialized clinic were examined. We selected adults of both sexes aged ≥ 18 who attended their first appointment between March and July 2017. Ordinal logistic regression models estimated the associations between number of PPTF (no previous treatment, 1 PPTF, 2, and ≥ 3 PPTF) and chronic migraine, the number of diagnosis exams performed, abortive drugs classes used, and non-pharmacological treatments tried (all categorized as none, 1- 3, and ≥ 4), and severe depression (PHQ-9 ≥ 15) and anxiety (GAD-7 ≥ 15), adjusted for sex, age, and years with disease.ResultsData from 440 patients (72.1 % female) with a mean (SD) age of 37.3 (13.0) years were analyzed. The frequency of no previous treatment was 37.7 % (166/440), while 31.8 % (140/440) showed ≥ 3 PPTF. In patients with ≥ 3 PPTF, 35.7 % (50/140) had episodic, and 64.3 % (90/140) had chronic migraine. Compared to no previous treatment, patients with ≥ 3 PPTF showed higher odds (95 % confidence interval) for chronic migraine [2.10 (1.47, 2.98)], ≥ 4 diagnosis exams [6.59 (3.38, 12.84)], ≥ 4 abortive drug classes [16.03 (9.53, 26.94)], ≥ 4 non-pharmacological treatments [5.91 (3.07,11.35)], and severe depression [1.75 (1.07, 2.88)] and anxiety [1.73 (1.05, 2.85)]. ConclusionPatients first visiting a headache specialist had a high frequency of non-response treatment associated with higher migraine burden in terms of chronification, psychiatric comorbidity, acute medication and non-pharmacological treatment inefficacy, and unnecessary exams.
Two new species of Hechtia (Bromeliaceae; Hechtioideae) from Jalisco, Mexico
Authors: Flores-Argüelles Alejandra , Hernández-Cárdenas Rodrigo Alejandro , Rosales-Martínez Santiago , Espejo-Serna Adolfo , López-Ferrari Ana Rosa , Siekkinen Andrew 
Published: January 2024

Backgrounds and aims – The genus Hechtia (sensu lato) is distributed from the southern United States to northern Central America and includes 95 species. Recent botanical explorations, carried out in the Colima and Jalisco states in search of H. reticulata, led to the discovery of two new species. The aims of this work were to complete the morphological description of H. reticulata and describe these two new species.
Material and methods – This study was based on fieldwork and on the revision of literature, protologues, type material, and herbarium specimens. The specimens collected were prepared for storage in the herbarium, analysed, measured, and descriptions were made; measurements were taken from dried specimens. Due to their morphological similarities and the closeness of their populations, the proposed species are compared with H. reticulata.
Key results – We propose two new species of Hechtia for Mexico (H. costalegrensis and H. pacifica); an epitype and a complete description of H. reticulata are also provided. The diagnostic characters and morphological affinities of the new species are discussed, including complete morphological descriptions and images; a comparative table is presented, showing the morphological differences between the new species and H. reticulata. A distribution map of the taxa described here and of H. reticulata is included, as well as an identification key and a list of examined specimens of all Hechtia species known to date from Colima and Jalisco.
APLICAÇÃO DIDÁTICA DE QUEBRA-CABEÇAS DO JOGO EteRNA PARA O ENSINO SOBRE A EDIÇÃO E DOBRAMENTO DE MOLÉCULAS DE RNA
Authors: Luiz Isadora Lauris , Hassunuma Renato Massaharu , Garcia Patrícia Carvalho , Messias Sandra Heloisa Nunes 
Published: January 2024

Introdução: O EteRNA é um jogo e um recurso de pesquisa utilizado para edição e dobramento de moléculas de RNA. Com o desenvolvimento de técnicas de edição de RNA como o REPAIR (RNA Editing for Programmable A to I Replacement), pesquisadores de todo mundo tem concentrado seus esforços para o desenvolvimento de novas pesquisas baseadas na edição de RNA. Objetivos: Analisar os quebra-cabeças do nível Introduction to RNA do jogo EteRNA e desenvolver uma proposta didática para utilizá-los em sala de aula como recurso didático no ensino de design de RNA. Material e métodos: Foram resolvidos os quatro quebra-cabeças do nível Introduction to RNA. Para cada quebra-cabeça foram apresentados: a) a tradução livre dos textos apresentados; b) orientações como cada quebra-cabeça pode ser resolvido; e c) propostas didáticas de conteúdos a serem apresentados ou discutidos em sala de aula pelo professor. Resultados: A análise dos quebra-cabeças do nível Introdution to RNA do jogo EteRNA mostrou que estes podem ser um excelente recurso didático que professores podem utilizar em sala de aula para apresentar a edição da molécula de RNA a seus alunos, e bem como tratar dos recursos utilizados para prever o dobramento deste ácido nucleico. Conclusões: Com o rápido avanço científico, é possível que a edição de ácidos nucleicos possa ser usada futuramente em humanos no tratamento de doenças genéticas e em recursos de Biotecnologia. Desta forma, é importante que esse assunto seja abordado em sala de aula, contextualizando os alunos destes novos recursos tecnológicos.
EVALUATING THE EFFICACY OF TECHNOLOGY INCUBATION CENTRES IN FOSTERING ENTREPRENEURSHIP: CASE STUDIES FROM THE GLOBAL SOUT
Authors: Simon Kaggwa  , Tochukwu Onunka  , Prisca Ugomma Uwaoma  , Okeoma Onunka  , Andrew Ifesinachi Daraojimba  , Nsisong Louis Eyo-Udo  
Published: January 2024

This study conducts a comprehensive evaluation of the effectiveness of Technology Incubation Centres (TICs) in nurturing entrepreneurship, focusing on case studies from diverse regions of the Global South. With the growing emphasis on innovation and technology-driven economic development, TICs have emerged as vital entities in fostering entrepreneurial ecosystems. The research employs a mixed-methods approach, combining quantitative analysis and qualitative case studies. The quantitative aspect involves assessing key performance indicators, including startup success rates, job creation, and financial sustainability of TICs. Qualitative investigations delve into the nuanced experiences of entrepreneurs, exploring the support mechanisms provided by TICs, challenges faced, and the overall impact on their ventures. The case studies span various contexts within the Global South, encompassing regions with differing economic, social, and cultural landscapes. By examining TICs in diverse settings, the study aims to draw insights into the contextual factors influencing the efficacy of incubation programs and their relevance in different entrepreneurial ecosystems. Preliminary findings suggest a correlation between the success of TICs and factors such as effective mentorship, access to funding, and collaborative networks. However, challenges such as resource constraints, regulatory hurdles, and variations in local market dynamics pose significant barriers to the optimal functioning of TICs. The study contributes to the existing literature by offering a nuanced understanding of the role and impact of TICs in the Global South. Findings will inform policymakers, entrepreneurs, and stakeholders about the specific contextual considerations that influence the efficacy of TICs, ultimately aiding in the refinement of strategies to enhance entrepreneurship and innovation in emerging economies. As the Global South increasingly positions itself as a hub for technological innovation, this research provides timely insights into the evolving landscape of entrepreneurial support structures, offering practical implications for the future development of TICs and fostering a conducive environment for sustained entrepreneurial growth.
Keywords: Technology Incubation Centres, Entrepreneurship, Global South, Case Studies, Innovation, Economic Development.
REVIEW OF BIG DATA IN FMCG SUPPLY CHAINS: U.S. COMPANY STRATEGIES AND APPLICATIONS FOR THE AFRICAN MARKET
Authors: Osato Itohan Oriekhoe  , Bankole Ibrahim Ashiwaju  , Kelechi Chidiebere Ihemereze  , Uneku Ikwue  
Published: January 2024

This review explores the strategic utilization of Big Data in Fast-Moving Consumer Goods (FMCG) supply chains, shedding light on the approaches adopted by U.S. companies and the potential applications for the evolving African market. As technology transforms the landscape of supply chain management, U.S. companies are at the forefront of leveraging Big Data analytics to optimize efficiency, enhance visibility, and respond dynamically to consumer demands. The analysis delves into the specific strategies employed by U.S. FMCG companies, ranging from predictive analytics for demand forecasting to real-time tracking for logistics optimization. Furthermore, the review investigates the adaptability and relevance of these strategies to the unique challenges and opportunities presented by the African market. The exploration of successful case studies, challenges, and potential solutions provides valuable insights for both U.S. companies seeking to expand into Africa and local businesses aiming to harness the power of Big Data for improved FMCG supply chain management. The findings contribute to the ongoing discourse on the intersection of technology, global supply chains, and the transformative potential of Big Data in shaping the future of FMCG distribution across continents.
Keywords: Big Data, Fast-Moving Consumer Goods, Analytics, Supply Chain Optimization, Demand Forecasting, Consumer-Centric, Data Security, Ethical Considerations.
REVIEW OF TECHNOLOGICAL ADVANCEMENTS IN FOOD SUPPLY CHAIN MANAGEMENT: A COMPARATIVE STUDY BETWEEN THE U.S. AND AFRICA
Authors: Osato Itohan Oriekhoe  , Bankole Ibrahim Ashiwaju  , Kelechi Chidiebere Ihemereze  , Uneku Ikwue  , Chioma Ann Udeh  
Published: January 2024

This comprehensive review explores the technological advancements in food supply chain management, presenting a comparative study between the United States and Africa. The global food supply chain faces numerous challenges, including demand volatility, perishability concerns, and the need for efficient and sustainable practices. This study delves into the contrasting landscapes of the U.S. and Africa, examining how each region adopts and adapts technology to address these challenges. The United States, as a developed nation, boasts an intricate and technologically sophisticated food supply chain. Advanced technologies such as blockchain, Internet of Things (IoT), and artificial intelligence are integrated to enhance transparency, traceability, and efficiency throughout the supply chain. From precision agriculture to smart logistics and distribution, the U.S. exemplifies a technology-driven approach to food supply chain management. In contrast, the African continent faces unique challenges, including infrastructural constraints, diverse agricultural practices, and the need for inclusive solutions. The study sheds light on how Africa leverages technology to overcome these challenges, showcasing innovations such as mobile-based supply chain platforms, data analytics for smallholder farmers, and blockchain for transparent transactions. By comparing the technological landscapes of the U.S. and Africa, this review identifies common trends, best practices, and region-specific innovations. Insights gained from this comparative study contribute to a holistic understanding of how technology transforms food supply chains on both global and regional scales. The findings aim to inform policymakers, industry stakeholders, and researchers, fostering cross-cultural learning and collaborative efforts to create resilient, sustainable, and technologically advanced food supply chains worldwide.
Keywords: Technological Advancements, Food, Supply Chain, Management, USA, Africa.
Studi Fenomologi: Kesejahteraan Psikologis pada Wanita Bekerja yang Mempunyai Anak Usia 0-6 tahun.
Authors: Aiman Rima Mudhiah Putri , Basaria Debora 
Published: January 2024

Menurut BPS (2022), jumlah wanita yang bekerja di Indonesia sebanyak 52,74 juta. Seorang wanita yang bekerja ialah seorang wanita yang mempunyai kegiatan di luar takdirnya sebagai wanita, lajang, maupun ibu rumah tangga. Biasanyamasa ini sebelum 30 tahun dimana masa tersebut merupakan masa yang produktif. Sebagai ibu rumah tangga atau istri yang juga diharapkan untuk bekerja dan meraih kesuksesan dalam karir, wanita mengalami suatu kendala konflik peran ganda yang tentunya kedua hal tersebut tak bisa diabaikan. Hal ini dikarenakan adanya nilai formal yang ada di masyarakat melalui pernikahan. Hal ini tentunya mempunyai dampak positif maupun negatif. Penelitian ini bertujuan untuk mendapatkan gambaran psychological well-being pada wanita bekerja yang mengalami konflik peran ganda. Metode yang digunakan untuk penelitian ini ialah kualitatif dengan purposive sampling. Hasil penelitian menunjukkan bahwa dimensi Psychological well-based, 3 dimensi telah dipenuhi oleh keempat partisipan adalah Purpose in Life, Environmental Mastery, dan Positive Relations with Others. Akan tetapi, selain ketiga dimensi tersebut terdapat beberapa partisipan yang belum menggambarkan dimensi seperti pada Self Acceptance, dan Personal Growth. Selain itu, pada dimensi Autonomy, Partisipan belum memenuhi gambaran tersebut. Kemudian pada dimensi Work family Conflict, dimensi yang ada telah dipenuhi dengan baik.
Uncertainty in the evolution of northwestern North Atlantic circulation leads to diverging biogeochemical projections
Authors: Rutherford Krysten , Fennel Katja , Garcia Suarez Lina , John Jasmin G. 
Published: January 2024

Abstract. The global ocean's coastal areas are rapidly experiencing the effects of climate change. These regions are highly dynamic, with relatively small-scale circulation features like shelf break currents playing an important role. Projections can produce widely diverging estimates of future regional circulation structures. Here, we use the northwestern North Atlantic, a hotspot of ocean warming, as a case study to illustrate how the uncertainty in future estimates of regional circulation manifests itself and affects projections of shelf-wide biogeochemistry. Two diverging climate model projections are considered and downscaled using a high-resolution regional model with intermediate biogeochemical complexity. The two resulting future scenarios exhibit qualitatively different circulation structures by 2075 where along-shelf volume transport is reduced by 70 % in one of them and while remaining largely unchanged in the other. The reduction in along-shelf transport creates localized areas with either amplified warming (+3 ∘C) and salinification (+0.25 units) or increased acidification (−0.25 units) in shelf bottom waters. Our results suggest that a wide range of outcomes is possible for continental margins and suggest a need for accurate projections of small-scale circulation features like shelf break currents in order to improve the reliability of biogeochemical projections.
الدراسات الاكتوارية واهميتها في المجالات المختلفة
Authors: المغربي عبد العزيز 
Published: January 2024

تمثلت مشكلة البحث في عدم ادراك ومعرفة المعنى العلمي لكلمة "الاكتوارية" لمعظم المؤسسات بالدولة , وعدم وجود ثقافة الدراسات الاكتوارية والوعي بأهميتها بالمؤسسات المالية المختلفة في ليبيا حيث نسعى من خلال هذا البحث الى إعطاء فكرة ونبذة عن أهمية الدراسات الاكتوارية في المؤسسات المختلفة والعمل على نشر الثقافة الاكتوارية في المجتمع و مدى اهميتها في الحفاظ على المركز المالي للمؤسسات حيث أشار البحث بان العلم الاكتواري يقوم بتقييم المخاطر المالية لجميع المؤسسات المالية مثل المصارف، شركات التامين، وسوق الأوراق المالية، وأنظمة التأمين الاجتماعي، وهيئة الرقابة على المال, وزارة المالية ,و وزارة الاستثمار, كما اشارت نتائج البحث بان الخبير الاكتواري يجب ان يكون متمرس في النظريات والتطبيقات في علوم الرياضيات والإحصاء والاقتصاد وحساب الاحتمالات والعلوم المالية ،كما تهدف الدراسات الاكتواري الى ضمان جدوى واستمرارية الأنظمة المالية والحــــــد مــــــن المخاطــــــر الماليــــــة المستقبلي وضمـــــــــــان أعلــــــــــى عائـــــــــد علـــــى الاستثمار كما تم التطرق الى تجربة ليبيا في الدراسات الإكتوارية لتحقيق الأهداف التي أنشئ من أجلها والتي في مقدمتها إجراء الدراسات الإكتوارية لصندوق الضمان الاجتماعي، بالإضافة الى توطين العلم الإكتواري محلياً , بالإضافة الى بناء نظام إكتواري يجعل من الدراسات الاكتوارية مصدراً أساسياً يعول عليه في اتخاذ القرارات الإستراتيجية وتوطين الأبحاث العلمية لحل كافة المشاكل المهنية , ويوصي البحث بان يتم اعداد ورش العمل وندوات بخصوص أهمية الدراسات الاكتوارية في مساعدة مؤسسات الدولة في اتخاذ القرارات الإستراتيجية و حث المؤسسات التعليمية على تبني خطة تعليمية لتوطين العلم الاكتواري بالجامعات الليبية , والاستعانة بالتجارب المحلية والدولية في المجال الاكتواري .
Experiencias de cuidados comunitarios en Pamplona: claves de desarrollo y desafíos para su extensión.
Authors: Canals Botas Leonor , Martínez-Virto Lucía 
Published: January 2024

En los últimos años la comunidad ha comenzado a posicionarse como un actor clave en la provisión de los cuidados, reconociéndose y surgiendo diferentes experiencias y organizaciones que abordan los cuidados desde lo comunitario. Esta atención a los cuidados comunitarios viene posicionándose en el centro del debate tanto en lo referido a las políticas públicas, como en los ámbitos académico y social.
El objetivo de esta investigación es ofrecer una aproximación a las experiencias con enfoque comunitario en Pamplona que cubren una parte de los cuidados en los grupos de edad de 0-3 años, menores y adolescentes y personas mayores. Para ello, se ha realizado un mapeo de las diferentes experiencias de cuidados comunitarios presentes en la comarca de Pamplona en el año 2018, seguido de un análisis en profundidad de 10 experiencias seleccionadas mediante de la realización de entrevistas en profundidad. Posteriormente se han identificado los objetivos, colectivos, potencialidades y limitaciones que presentaban las mismas en los años 2018-2019.
Los resultados aportan una visión global sobre estas experiencias, permitiendo acercarnos a las mismas y determinar si suponen un elemento de transformación social y democratización de los cuidados. Se ha podido comprobar un aumento significativo de experiencias, de la mano de una ampliación en sus contenidos y poblaciones que las conforman. Así mismo, los resultados permiten abrir elementos de reflexión en torno a la gestión de los cuidados comunitarios, su posible vinculación con los poderes públicos y algunos factores que influyen negativamente en su consolidación.