bluuebunny/crossref_metadata_2025_split huggingface dataset:
Stena Multilayer Flow Modulator in Aortic Aneurysms: An Overview Based on Preclinical Experience
Authors: Tanyeli Omer , Kaya Sez , Beyaz Metin Onur , Fansa Iyad , Görmus Niyazi 
Published: November 2023

Abstract
Background: Aortic aneurysm (AA) is still an important public health problem worldwide. Endovascular aneurysm repair (EVAR) is currently primary treatment option because of the side effects of surgery. Significant efforts are being made to reduce the AA-associated adverse events. In this article, the multilayer flow modulator approach is discussed based on the results of patients treated with Stena Multilayer Flow ModulatorⓇ (S-MFM) (Invamed, Ankara) by reviewing literatures published on the subject.
Material Methods: It was evaluated 6-month follow-up outcomes of 12 patients (nine men and three females; mean age 60 years, range 34-79 years) underwent aneurysm repair with the S-MFM between July 2022 and December 2022.
Results: The control angiograms confirmed successful patency in the lumen of the main aorta and the branches in all cases. The technical success was 100%, and no case required immediate intervention. Significant complications such as ruptures, stent migrations, retractions, thrombosis, fractures were not observed. No endoleak associated with the at the proximal and distal ends was observed.
Conclusions The current data show the multilayer flow modulator approach may be an attractive alternative to surgery or EVAR for aortic aneurysm. While it shrinks the aneurysm sac and protects the side branch blood flow, it reduces the risks of mortality and morbidity. It can be easily applied in complex aortic aneurysms and its ready-to-use structure that does not require personalized production shortens the waiting time for intervention. Further research and longer follow-up are needed.
The relationship between eating behavior and anxiety, depression, and comorbidity among rural residents in China
Authors: Liu Xiaojun , Chen Yating , Chang Huajing , Ruan Wenqian , Cai Longhua , Zhang Lingling 
Published: November 2023

Abstract
Introduction
This study examined the association between eating behavior and anxiety, depression, and comorbidity among rural residents.
Methods
This cross-sectional study used data from the Adult Chronic Disease and Nutrition Surveillance program in Pingnan. Healthy diet scores and dietary patterns were used to assess eating behavior. Two-Step Cluster Analysis (TCA) was employed to determine the dietary patterns. The Generalized Anxiety Disorder-7 (GAD-7) and the Patient Health Questionnaire-9 (PHQ-9) were applied to estimate anxiety and depression symptoms, respectively. Binary logistic regression models were conducted to explore the effects of healthy diet scores and dietary patterns on anxiety, depression, and comorbidity.
Results
Binary logistic regression results showed that rural residents with a healthy diet score of 0 and 1 were associated with a higher detection rate for anxiety (OR = 2.53, 95% CI = 1.29–4.96; OR = 2.31, 95% CI = 1.23–4.36, respectively), depression (OR = 2.65, 95% CI = 1.24–5.66; OR = 2.47, 95% CI = 1.20–5.05, respectively), and comorbidity (OR = 3.15, 95% CI = 1.27–7.84; OR = 2.42, 95% CI = 1.01–5.78, respectively). Those who had “moderately healthy pattern” and “unhealthy pattern” were associated with a higher detection rate of anxiety (OR = 1.67, 95% CI = 1.20–2.34; OR = 1.69, 95% CI = 1.14–2.50, respectively), depression (OR = 1.67, 95% CI = 1.17–2.39; OR = 1.61, 95% CI = 1.05–2.45, respectively), and comorbidity (OR = 1.88, 95% CI = 1.20–2.95; OR = 2.15, 95% CI = 1.29–3.57, respectively).
Conclusions
Unhealthy eating behavior may be associated with a higher detection rate of anxiety, depression, and comorbidity in rural residents. It is critical to implement dietary intervention programs for rural residents to develop healthy eating behavior attributed to reductions in anxiety and depression.
Hemorrhagic pericardial tamponade in a hemodialysis patient with catheter- related superior vena cava syndrome: A case report
Authors: Zhao Xiaohong , Wang Kang 
Published: November 2023

Abstract
Background Iatrogenic complications of intravascular treatment for central venous stenosis have not yet been reported.Case presentation Here we present a case of a 72-year-old male patient on maintenance hemodialysis who developed catheter-related superior vena cava syndrome and subsequently suffered from hemorrhagic pericardial tamponade after undergoing percutaneous transluminal angioplasty and stenting. The patient initially presented with dysfunction of the dialysis catheter (a cuffed tunneled double-lumen catheter in the right internal jugular vein). Imaging examination revealed clear occlusion of the downstream superior vena cava, significant compensatory dilatation of the azygos vein, and abundant subcutaneous collaterals. The patient underwent percutaneous transluminal angioplasty and stenting of the superior vena cava. Unfortunately, postoperative hemorrhagic pericardial tamponade occurred and the patient developed cardiogenic shock.Conclusions The case emphasizes the need for increased attention to iatrogenic endovascular injuries during catheter placement and intravascular treatment.
Neural temporal dynamics of negative emotional symptoms after iTBS in patients with stroke: a TMS-EEG study
Authors: Liu Qian , Yang Xue , Zhang Hongmei , Lu Yihuan , Chen Xueting , Wang Tianling , Yao Liqing 
Published: November 2023

Abstract
Background
Stroke pathogenesis may be linked with aberrant neural network connections between brain regions and synapses plasticity. Furthermore, depression following a stroke does not arise from dysregulation in a singular brain region but rather from alterations across a “depression network”. While intermittent theta burst stimulation (iTBS) has been shown to alleviate depressive symptoms and modulate brain networks, but the effects of iTBS stimulation of the cerebellum on post-stroke negative emotional symptoms remain unexplored. Transcranial magnetic stimulation-electroencephalography (TMS-EEG) can offer insights into the dynamic mechanisms underlying iTBS treatment in stroke patients.
Objectives
The study aims to investigate the temporal dynamics of the power spectrum and functional connectivity in post-stroke patients following iTBS over the cerebellum and to determine if iTBS targeting the cerebellum alters negative emotional symptoms in these patients.
Methods
Twelve subacute stroke patients were enrolled, baseline data, along with clinical characteristics, were documented. Patients underwent iTBS treatment. Resting state EEG data were collected before and after in the initial and concluding iTBS sessions. Analyses were conducted on some indicators.
Results
Under different periods’ iTBS intervention, in both the Alpha and Beta1 bands, there was a significant difference in the power spectrum and phase synchronization within regions of interest in stroke patients. A significant correlation was observed between phase synchronization and the self-rating depression scale score.
Conclusions
In different periods, administering iTBS to target the cerebellum influenced the power spectrum, functional connectivity, and negative emotional symptoms in stroke patients.
Family medicine residents’ perspectives about patient partners in teaching participation in their training: A retrospective case study using a mixed-method explanatory sequential design
Authors: Deslauriers Tania , Tremblay Alexandre , Bihan Hélène , Codsi Marie-Pierre , Rouly Ghislaine , Leclaire Marie , Riendeau Tania , Leclerc Mylène , Yapi Sopie Marielle , Layani Géraldine 
Published: November 2023

Abstract
Objective: To explore the perspective of family medicine residents (FMRs) about patient partners in teaching participation in the practice-based learning program (PBLP) offered in university family medicine groups (U-FMG).
Participants and methods: The study was carried out among first- and second-year FMRs who completed their doctorate/externship in Quebec and attended the PBLP workshop involving a patient partner in teaching from U-FMG Notre-Dame. FMRs completed a questionnaire at the end of the PBLP workshop, and quantitative data were analyzed descriptively. Then, a focus group was conducted with some of these FRMs. The results were analyzed by two co-coders using DedooseÒ software.
Results: All FRMs (n=16) completed the questionnaire, and 4 FRMs participated in the focus group. The majority of FRMs mentioned having improved their knowledge of care offered in partnership with patients after the workshop but not their understanding of patients' rights. Two major themes emerged from the analysis: 1) knowledge and skills sought and 2) factors influencing the partnership with the patient partner in teaching.
Conclusion: The contribution of patient partners in teaching to the training of FRMs is promising and could be evaluated more extensively to improve the quality of training. The FRMs raised several avenues for improvement.
Evaluating the performance of Plasmodium falciparum genetics for inferring National Malaria Control Program reported incidence in Senegal
Authors: Wong Wesley , Schaffner Stephen F. , Thwing Julie , Seck Mame Cheikh , Gomis Jules , Diedhiou Younouss , Sy Ngayo , Ndiop Medoune , Ba Fatou , Diallo Ibrahima , Sene Doudou , Diallo Mamadou Alpha , Ndiaye Yaye Die , Sy Mouhamad , Sene Aita , Sow Djiby , Dieye Baba , Tine Abdoulaye , Ribado Jessica , Suresh Joshua , Lee Albert , Battle Katherine E. , Proctor Joshua L , Bever Caitlin A , MacInnis Bronwyn , Ndiaye Daouda , Hartl Daniel L. , Wirth Dyann F , Volkman Sarah K 
Published: November 2023

Abstract
Genetic surveillance of the Plasmodium falciparum parasite shows great promise for helping National Malaria Control Programs (NMCPs) assess parasite transmission. Genetic metrics such as the frequency of polygenomic (multiple strain) infections, genetic clones, and the complexity of infection (COI, number of strains per infection) are correlated with transmission intensity. However, despite these correlations, it is unclear whether genetic metrics alone are sufficient to estimate clinical incidence. Here, we examined parasites from 3,147 clinical infections sampled between the years 2012–2020 through passive case detection (PCD) across 16 clinic sites spread throughout Senegal. Samples were genotyped with a 24 single nucleotide polymorphism (SNP) molecular barcode that detects parasite strains, distinguishes polygenomic (multiple strain) from monogenomic (single strain) infections, and identifies clonal infections. To determine whether genetic signals can predict incidence, we constructed a series of Poisson generalized linear mixed-effects models to predict the incidence level at each clinical site from a set of genetic metrics designed to measure parasite clonality, superinfection, and co-transmission rates. We compared the model-predicted incidence with the reported standard incidence data determined by the NMCP for each clinic and found that parasite genetic metrics generally correlated with reported incidence, with departures from expected values at very low annual incidence (<10/1000/annual [‰]). When transmission is greater than 10 cases per 1000 annual parasite incidence (annual incidence >10 ‰), parasite genetics can be used to accurately infer incidence and is consistent with superinfection-based hypotheses of malaria transmission. When transmission was <10 ‰, we found that many of the correlations between parasite genetics and incidence were reversed, which we hypothesize reflects the disproportionate impact of importation and focal transmission on parasite genetics when local transmission levels are low.
A Spatio-Temporal Probabilistic Neural Network to Forecast COVID-19 Counts
Authors: Ravenda Federico , Cesarini Mirko , Peluso Stefano , Mira Antonietta 
Published: November 2023

Abstract

Geo-referenced and temporal data are becoming more and more ubiquitous in a wide range of fields such as medicine and economics. Particularly in the realm of medical research, spatio-temporal data play a pivotal role in tracking and understanding the spread and dynamics of diseases, enabling researchers to predict outbreaks, identify hot-spots, and formulate effective intervention strategies.To forecast these type of data we propose a Probabilistic Spatio-Temporal Neural Network that (1) estimates, with computational efficiency, models with spatial and temporal components; and (2) combines the flexibility of a Neural Network - which is free from distributional assumptions -with the uncertainty quantification of probabilistic models. Our architecture is compared with the established INLA method, as well as with other baseline models, on COVID-19 data in Italian regions. Our empirical analysis demonstrates the superior predictive effectiveness of our method across multiple temporal ranges and offers insights for shaping targeted health interventions and strategies. The codebase is available to facilitate reproduciblity at the following link:
https://github.com/Fede-stack/Probabilistic-COVID19
Amphipod-Crustacea: a potential live feed for mud crab culture
Authors: Sulaeman Sulaeman , Herleniah Herlinah , Gunarto Gunarto , Nurfadila Nurfadila 
Published: November 2023

Abstract

Mud crab (Genus: Scylla) is among the most popular seafood in the world. Cannibalism is a major bottleneck in the development of commercial aquaculture of Scylla paramamossain. Artificial feed is generally less attractive for the crablet stage and believed that more appropriate live feed will be preferred. Two sets of experiments were conducted to evaluate if Amphipod-crustacea may be used as live prey for mud crabs. The first experiment was to test the consumption rate of four days old crablet against amphipods. The experiment was conducted in glass containers with a 1 L capacity at varying density levels of Amphipod. The quantity of Amphipod consumed by a crablet over ten hours was evaluated. The second experiment was to test the ability of different sizes of mud crabs on amphipod prey. The results indicated that the consumption rate increases considerably (P < 0.05) when the density of amphipods rises and peaks at 30.3 ind./crab. However, mud crabs' preying ability on amphipods was significantly reduced as their size increased. At about 24 g body weight, crab juveniles could consume 50% of the provided amphipod during exposure. It may be then inferred that the amphipod is applicable as a live food during the weaning of mud crabs. This is the first study of successful feeding mud crab juveniles on alive amphipods and suggests that amphipods can be developed as the primary feed during weaning. However, research about amphipods' influence on the mud crab's growth rate is still needed.
The transcriptomic insight into the differential susceptibility of African Swine Fever in inbred pigs
Authors: Banabazi Mohammad Hossein , Freimanis Graham , Goatley Lynnette , Netherton Christopher L , de Koning Dirk-Jan 
Published: November 2023

Abstract

African swine fever (ASF) is a global threat to animal health and food security. ASF is typically controlled by strict biosecurity, rapid diagnosis and culling of affected herds. Much progress has been made in developing modified live virus vaccines against ASF. There is host variation in response to ASF infection in field and controlled conditions. To better understand the dynamics underlying this host differential morbidity, whole transcriptome profiling was carried out in twelve immunized and five sham immunized pigs. Seventeen MHC homozygous inbred Large white Babraham pigs were sampled at three time points before and after challenge. The changes in the transcriptome profiles of infected animals were surveyed over time. In addition, the immunization effect on the host response was studied as well among the contrasts of all protection subgroups. The results showed two promising candidate genes to distinguish between resilient and susceptible pigs with a virulent African swine fever virus (ASFV) pre-infection: HTRA3 and GFPT2 (padj < 0.05). Variant calling on the transcriptome assemblies showed a two-base pair insertion into the ACOX3 gene closely located to HTRA3 that may regulate its expression as a putative genomic variant for ASF. Several significant DGEs, enriched gene ontology (GO) terms, and KEGG pathways at one-day and one-week post-infection, compared to the pre-infection, indicate a significant inflammation response immediately after ASF infection. The presence of the virus was confirmed by the mapping of RNA-Seq reads on two whole viral genome sequences. This was concordant with a higher virus load in the non-recovered animals one-week post-infection. There was no transcriptome signature on the immunization at pre-infection and one-day post-infection. More samples and data from additional clinical trials may support these findings.
Assessing the Impact of Written Corrective Feedback Strategies on the Writing Proficiency of Senior High School Students
Authors: Rasool Ushba , Qian Jiancheng , Gao Min , Wang Huang , Hossain Alamgir 
Published: November 2023

Abstract

Researchers have attempted to explore the effects of written corrective feedback (WCF) on learners’ language learning performance for a long time. How to provide feedback, when to provide WCF and how much to provide are some serious concerns of linguists. Much research has been conducted involving adults, while little has been done to consider senior high school students in this regard. This study has been aimed to explore the effects of direct WCF, indirect WCF and metalinguistic explanation on the writing performance of senior high school students in Pakistan. Students were divided into four groups, each with one type of feedback, including group four as the control group with no feedback. All four groups had written narration on a given picture and were treated by mentioned feedback. After that, results were compared to look for effective feedback type. After writing tests, a survey was conducted to explore students’ perceptions about WCF and WCF strategies. The study found that learners want feedback from their teachers and prefer direct feedback and Metalinguistic explanation. This research has been planned to help learners in their early stage through WCF learn a second language and form a strong linguistic base that will help them construct grammatically correct sentences and compositions.
2021 UK floods: event summaries and reflections from the Flood Forecasting Centre
Authors: Pilling Charles , Millard Jon , Perez Julia , Turner Russell , Duke Anthony , Egan Katie 
Published: November 2023

Abstract
Flooding in 2021 has highlighted the increased risk to national resilience. This is against a backdrop of the UK climate projected to become more extreme over the next few decades. This paper considers the notable river and surface water flood events within England and Wales during 2021 and examines the performance of the Flood Forecasting Centre in highlighting the flood risk to our customers. We reflect on team debriefs as well as feedback and surveys from our customers. We distil our learnings and make connections with improvements in our underpinning science, forecasting tools, products and services. Finally, we highlight challenges associated with surface water flooding and suggest how we may collectively start to overcome these.
Current Targets and Future Directions of Positive Inotropes for Heart Failure
Authors: Fairuz Shadreen , Ang Chee Wei , Mraiche Fatima , Goh Joo Kheng 
Published: November 2023

:
While a congestive heart failure patient will ultimately need an assist device
or even a replacement heart as the disease progresses, not every patient is qualified for
such advanced therapy. Such patients awaiting better circulatory support benefit from
positive inotropes in the meantime as palliative care. These agents are often prescribed
in patients with acute decompensated heart failure, with reduced left ventricular ejection
fraction and symptoms of organ dysfunction. Although positive inotropes, for example,
digoxin, dobutamine, milrinone, levosimendan, etc., are successfully marketed and in
use, a lot of their adverse effects, like arrhythmias, hypotension, and even sudden cardiac
death, are rather encouraging further research on the development of novel positive inotropes.
This review has investigated the molecular mechanisms of some of these adverse
effects in terms of the proteins they target, followed by research on newer targets.
Studies from 2013-2023 that have reported new small molecules with positive inotropic
effects have been revisited in order to determine the progress made so far in drug discovery.
Diabetic Wound: Pathophysiology, Complications and Treatment
Strategies
Authors: Chauhan Sunita , Gulia Monika , Singh Rahul Pratap , Jhawat Vikas 
Published: November 2023

Abstract:
Diabetic wound healing is expected to affect 25% of all diabetics, resulting in less severe external factors, economic costs, and less trauma. Topical formulations have been continually
improved to achieve a range of amazing properties and have had a significant impact on the management of diabetic wounds. Topical insulin has become one of the most attractive and convenient
wound healing techniques due to its excellent biocompatibility, water retention, and therapeutic
properties. Multiple versatile topical insulins have been identified and have shown promise over
the past few years as they greatly facilitate the management of diabetic wounds as we understand
their etiology. The physiological wound healing process repairs damaged tissue and restores skin
integrity. For about a century, insulin, a powerful healing agent, and it has been utilized in several
clinical and experimental researches research studies to accelerate the healing of various injuries.
The Antimicrobial Activities of Nanoparticles against Helicobacter Pylori:
A Systematic Review
Authors: Shakib Pegah , Saki Reza , Goudarzi Gholamreza , Zolfaghari Mohammad Reza 
Published: November 2023

Background:
nanoparticles against Helicobacter pylori in the
world. Therefore, this systematic review aims to investigate nanoparticles' antimicrobial activities
against Helicobacter pylori

Methods:
All articles published from 2000 to 2023 from Scopus, PubMed, Science Direct, Cochrane,
and Ovid databases with keywords Helicobacter pylori, H.pylori, nanoparticles, solid lipid NPS, and
lipid nanocarrier were extracted and transferred to EndNote X9 software by two researchers.

Results:
During the first stage, 280 articles were chosen. Following the application of the
eligibility criteria for inclusion/exclusion, 37 studies were ultimately selected, considering the
removal of duplicates, irrelevant articles, and those containing complete text. In the present
systematic review study, most nanoparticles used against Helicobacter pylori were polymericbased nanoparticles.

Conclusion:
The results indicate the high potential of various nanoparticles against Helicobacter
Pylori. Therefore, the results show that these nanoparticles have the potential to prepare antiHelicobacter Pylori nanoparticles. In addition, these nanoparticles have fewer side effects than
chemical drugs.