bluuebunny/crossref_metadata_2025_split huggingface dataset:
RETRACTED: Effects of fast‐track recovery programme on the surgical site wound infection in patients undergoing biliary stones surgery: A meta‐analysis
Authors: Zhou Anyi , Lv Xiuhong , Wang Le , Wang Huan , Lu Mingshu 
Published: January 2024

AbstractTo systematically evaluate the effects of a fast‐track recovery programme on perioperative wound infections and postoperative complications in patients undergoing biliary tone surgery, we conducted a comprehensive search of PubMed, Web of Science, Cochrane Library, Embase, China Biomedical Literature Database, Wanfang and China National Knowledge Infrastructure databases from inception to 29 September 2023 for randomised controlled trials (RCTs) focusing on the application of a fast‐track recovery programme in patients undergoing biliary stone surgery. Two researchers independently screened and evaluated the studies based on predefined inclusion and exclusion criteria, and data were subsequently extracted from the included studies. Stata software (version 17.0) was employed for data analysis. Overall, 19 RCTs involving 2363 patients were included, with 1178 patients allocated to the fast‐track recovery programme group and 1185 to the conventional care group. The results revealed a significantly lower occurrence of wound infection (3.74% vs. 9.45%, OR = 0.36, 95% CI: 0.25–0.51, p < 0.001) and postoperative complications (11.38% vs. 27.34%, OR = 0.31, 95% CI: 0.25–0.39, p < 0.001) in the fast‐track recovery programme group compared to the conventional care group. The available evidence supports the assertion that implementing a fast‐track recovery programme in the perioperative period of patients undergoing biliary stone surgery effectively reduces the incidence of wound infections and postoperative complications while facilitating postoperative recovery.
Effect of different surgical techniques on postoperative wound infection in patients with uterine prolapse: A meta‐analysis
Authors: Wang Jinyun , Shang Xianping , Huang Jingjie , Wang Jing 
Published: January 2024

AbstractThe assumption is that a number of controlled trials have been conducted to assess the impact of uterus retaining or hysterectomy on wound and haemorrhage, but there is no indication as to which method would be more beneficial for wound healing. This research is intended to provide a comprehensive overview of the availability of wound healing in case studies of both operative methods. From inception to October 2023, four databases were reviewed. The odds ratio (OR) and the mean difference (MD) for both groups were computed with a random effect model, as well as the corresponding 95% confidence intervals. A total of five studies were carried out in the overall design and enrolled 16 972 patients. No statistical significance was found in the rate of postoperative wound infection among the two treatments (OR,1.46; 95% CI,0.66,3.22 p = 0.35); The rates of bleeding after surgery did not differ significantly from one procedure to another (OR,1.41; 95% CI,0.91,2.17 p = 0.12); two studies demonstrated no statistical significance for the rate of incisional hernia after surgery (OR,2.58; 95% CI,0.37,18.05 p = 0.34). Our findings indicate that there is a similar risk between uterine preservation and hysterectomies for the incidence of wound infection, haemorrhage and protrusion of incision.
Surgical site infection outcomes of two different closed incision negative pressure therapy systems in cardiac surgery: Systematic review and meta‐analysis
Authors: Loubani Mahmoud , Cooper Matthew , Silverman Ronald , Bongards Christine , Griffin Leah 
Published: January 2024

AbstractClosed incision negative pressure therapy (ciNPT) system use compared with standard of care dressings (SOC) on surgical site infection (SSI) in cardiac surgery was assessed. A systematic literature review was conducted. Risk ratios (RR) and random effects models were used to assess ciNPT with foam dressing (ciNPT‐F) or multilayer absorbent dressing (ciNPT‐MLA) versus SOC. Health economic models were developed to assess potential per patient cost savings. Eight studies were included in the ciNPT‐F analysis and four studies were included in the ciNPT‐MLA analysis. For ciNPT‐F, a significant reduction in SSI incidence was observed (RR: 0.507, 95% confidence interval [CI]: 0.362, 0.709; p < 0.001). High‐risk study analysis reported significant SSI reduction with ciNPT‐F use (RR: 0.390, 95% CI: 0.205, 0.741; p = 0.004). For ciNPT‐MLA, no significant difference in SSI rates were reported (RR: 0.672, 95% CI: 0.276, 1.635; p = 0.381). Health economic modelling estimated a per patient cost savings of $554 for all patients and $3242 for the high‐risk population with ciNPT‐F use. Health economic modelling suggests ciNPT‐F may provide a cost‐effective solution for sternotomy incision management. However, limited high‐quality literature exists. More high‐quality evidence is needed to fully assess the impact of ciNPT use following cardiac surgery.
The Welfare Argument for Free Time Protection
Authors: Jauch Malte 
Published: January 2024

ABSTRACTDemands for free time protections are often justified with appeal to a concern for individuals' welfare. The idea is that people would enjoy greater levels of welfare if they had more access to free time. This article shows that the currently most sophisticated version of the welfare argument is inconclusive. It then shows how this argument can be modified and extended to become conclusive. The main claim is that policymakers have a decisive welfare‐based reason to implement free time protections that go even further than those already in place in countries that are known for their good work–life balance.
Single immediate implant placement in the maxillary aesthetic zone with and without connective tissue grafting: Results of a 5‐year randomized controlled trial
Authors: Zuiderveld Elise G. , Meijer Henny J. A. , Gareb Barzi , Vissink Arjan , Raghoebar Gerry M. 
Published: January 2024

AbstractAimTo assess the 5‐year effects of grafting connective tissue while undertaking single immediate implant placement and provisionalization at the mid‐buccal mucosa level (MBML). Secondary outcomes were buccal bone wall thickness (BBT), marginal bone level (MBL) and patient satisfaction.Materials and MethodsSixty patients with a single failing tooth in the maxillary anterior region were provided with an immediately placed and provisionalized implant. At implant placement, the patients randomly received either a connective tissue graft from the maxillary tuberosity (n = 30, test group) or no graft (n = 30, control group). The alveolar socket classification was mainly Type 2A. Data were collected before removing the failing tooth (T0), and at 1 (T1), 12 (T12) and 60 (T60) months after final crown placement. The primary outcome was the change in MBML compared with the pre‐operative situation. Additionally, the change in BBT, MBL, aesthetics (using the Pink Aesthetic Score–White Aesthetic Score), soft‐tissue peri‐implant parameters and patient satisfaction were assessed.ResultsAt the 5‐year follow‐up, 27 patients could be analysed from each group. In each group, one implant was lost during the osseointegration period, within 3 months of placement, resulting in an implant survival rate of 96.7% in both groups. MBML change at T60 was −0.6 (−1.1 to –0.1) mm in the control group and 0.1 (−0.4 to 0.5) mm in the test group (p = .008). BBT and MBL, aesthetics, soft‐tissue peri‐implant parameters and patient satisfaction showed stable results and satisfied patients, without clinically relevant differences between the groups.ConclusionsThis 5‐year follow‐up study shows that grafting connective tissue when replacing a single failing tooth with immediately placed and provisionalized implant results in favourable peri‐implant tissues and fewer MBML changes.
Metabolic syndrome, its components, and gastrointestinal cancer risk: a meta‐analysis of 31 prospective cohorts and Mendelian randomization study
Authors: Zhan Zhi‐Qing , Chen Ying‐Zhou , Huang Ze‐Min , Luo Yu‐Hua , Zeng Jia‐Jian , Wang Ye , Tan Juan , Chen Ying‐Xuan , Fang Jing‐Yuan 
Published: January 2024

AbstractBackground and AimCohort studies have linked metabolic syndrome (MetS) to gastrointestinal (GI) cancer risk. We aimed to evaluate the associations between MetS, its components, and combinations of MetS components with eight GI cancers risk.MethodsWe conducted a systematic search of prospective cohort studies and performed a meta‐analysis. Subgroup analyses regarding diagnostic criteria, sex, cancer sites, histological subtypes, ethnic groups, and studies adjusted for alcohol consumption were carried out. Mendelian randomization (MR) was employed to evaluate the causality between 17 MetS‐related traits and eight GI cancers among Europeans and Asians separately.ResultsMeta‐analyses of 31 prospective studies indicated that MetS was significantly associated with an increased risk of colorectal cancer (CRC) (RR [95% CI] = 1.13 [1.12–1.15]), esophageal cancer (EC) (RR [95% CI] = 1.17 [1.03–1.32]), gallbladder cancer (GBC) (RR [95% CI] = 1.37[1.10–1.71]), liver cancer (LC) (RR [95% CI] = 1.46 [1.29–1.64]), and pancreatic cancer (PaC) (RR [95% CI] = 1.25 [1.20–1.30]), but not gastric cancer (GC) (RR [95% CI] = 1.11 [0.96–1.28]). Regarding the associations between MetS components and GI cancers risk, the following associations showed statistical significance: obesity‐CRC/LC/EC/, hypertriglyceridemia‐LC/PaC, reduced high‐density lipoprotein (HDL)‐CRC/LC/GC/PaC, hyperglycemia‐CRC/LC/PaC, and hypertension‐CRC/LC/EC/PaC. Sex‐specific associations were observed between individual MetS components on GI cancers risk. Among the top three common combinations in both sexes, obesity + HTN + hyperglycemia had the strongest association with CRC risk (RR [95% CI] = 1.54 [1.49–1.61] for males and 1.27 [1.21–1.33] for females). MR analyses revealed causality in 16 exposure–outcome pairs: waist‐to‐hip ratio/BMI/HbA1c‐CRC; BMI/childhood obesity/waist circumference/T2DM/glucose‐EC; BMI/waist circumference/cholesterol‐LC; cholesterol/childhood obesity/waist circumference/HbA1c‐PaC; and HbA1c‐GBC. These results were robust against sensitivity analyses.ConclusionsSince MetS is reversible, lifestyle changes or medical interventions targeting MetS patients might be potential prevention strategies for GI cancers.
Efficacy of endoscopic ultrasound‐guided tissue acquisition using stereo‐microscopic on‐site evaluation for possible comprehensive genome profile in patients with advanced pancreatic cancer
Authors: Okuwaki Kosuke , Watanabe Masafumi , Yoshida Tsutomu , Tamaki Akihiro , Iwai Tomohisa , Adachi Kai , Ishizaki Junro , Hanaoka Taro , Imaizumi Hiroshi , Kida Mitsuhiro , Kusano Chika 
Published: January 2024

AbstractBackground and AimStereomicroscopic on‐site evaluation (SOSE) is a rapid evaluation method for endoscopic ultrasound‐guided tissue acquisition (EUS‐TA) with a high diagnostic sensitivity when the stereomicroscopically visible white core (SVWC) cut‐off value (≥ 11 mm) is met. We prospectively examined the association between SVWCs and the adequacy of tissue specimens, assuming subsequent comprehensive genome profiling (CGP).MethodsThis study included 66 consecutive patients with suspected unresectable pancreatic cancer who underwent EUS‐TA. The primary endpoint was the frequency of combined samples with ≥ 20% tumor cell content that met over twice the SVWC (T‐SVWC) cut‐off value, achieved through multiple punctures. The secondary endpoints were the number of punctures, the percentage of SVWC cut‐off values, adverse events, the positive diagnosis rate, and the tissue section area.ResultsThe median number of EUS‐TA punctures for suspected unresectable pancreatic cancer was 3 (range, 3–4); SVWC and T‐SVWC cut‐off values were obtained in 171/206 specimens and 65/66 patients, respectively. There were no EUS‐TA‐related adverse events. The positive diagnosis rate of EUS‐TA was 95.5%. Among the 63 patients meeting the T‐SVWC cut‐off value in pathological diagnoses, the median tumor cell content was 40% (range, 5–80%), with 57 patients having tumor cell content ≥ 20%. The median tissue section area was 15 (range, 3–40) mm2.ConclusionsWhen performing EUS‐TA for unresectable pancreatic cancer with the intention of subsequent CGP, obtaining a high tumor cell content (≥ 20%) by assessing the T‐SVWC cut‐off value via SOSE may serve as a novel indicator for on‐site estimation of CGP suitability for EUS‐TA specimens.
A behavioral gap in survival beliefs
Authors: Apicella Giovanna , De Giorgi Enrico G. 
Published: January 2024

AbstractLife span uncertainty (longevity risk) impacts several economic decisions. Individuals can form and revise their survival beliefs making use of behavioral heuristics. We propose a model of sentiment, in which individuals are assumed to switch between optimistic and pessimistic expectations of their health. When optimism is persistent in the face of health shocks, or when individuals are more likely to change their sentiment from pessimistic to optimistic than otherwise, our model predicts survival underestimation at young ages and overestimation at old ages. An empirical analysis based on the longitudinal data from Survey of Health, Ageing and Retirement in Europe validates our model.
Effect of serving temperatures on retronasal detection thresholds of capsaicin and dihydrocapsaicin among Korean consumers
Authors: Lee Juyeon , Chon Seo‐yeong , Kim Mina K. 
Published: January 2024

AbstractThe purpose of this study was to determine the retronasal threshold values of capsaicin and dihydrocapsaicin according to the change in serving temperatures. Threshold tests were performed using five series of three alternative forced choice method in aqueous‐based matrices at varying temperature levels. The retronasal threshold values of capsaicin at 4°C, 25°C, and 60°C were 1.83, 1.57, and 1.57 mg/kg, respectively; no significant differences were observed. Similarly, the retronasal threshold of dihydrocapsaicin at 4°C, 25°C, and 60°C reached 2.14, 1.71, and 1.78 mg/kg, respectively; no differences based on serving temperature were observed (p > .05). These values were slightly higher than best estimate thresholds reported in different countries.Practical ApplicationsCapsaicin and dihydrocapsaicin are two of the major compounds responsible for how we perceive spiciness in food. This study found no differences in best estimate thresholds (BETs) according to the temperature at which the food was served, suggesting that the serving temperature does not impact the recognition threshold of capsaicin and dihydrocapsaicin. This means that the serving temperature does not alter the human perceived spiciness in foods having capsaicin and dihydrocapsaicin above BET levels.
Effect of marine heatwaves and warming on kelp microbiota influence trophic interactions
Authors: Castro Louise C. , Vergés Adriana , Straub Sandra C. , Campbell Alexandra H. , Coleman Melinda A. , Wernberg Thomas , Steinberg Peter , Thomas Torsten , Dworjanyn Symon , Cetina‐Heredia Paulina , Roughan Moninya , Marzinelli Ezequiel M. 
Published: January 2024

AbstractThe range‐expansion of tropical herbivores due to ocean warming can profoundly alter temperate reef communities by overgrazing the seaweed forests that underpin them. Such ecological interactions may be mediated by changes to seaweed‐associated microbiota in response to warming, but empirical evidence demonstrating this is rare. We experimentally simulated ocean warming and marine heatwaves (MHWs) to quantify effects on two dominant temperate seaweed species and their microbiota, as well as grazing by a tropical herbivore. The kelp Ecklonia radiata's microbiota in sustained warming and MHW treatments was enriched with microorganisms associated with seaweed disease and tissue degradation. In contrast, the fucoid Sargassum linearifolium's microbiota was unaffected by temperature. Consumption by the tropical sea‐urchin Tripneustes gratilla was greater on Ecklonia where the microbiota had been altered by higher temperatures, while Sargassum's consumption was unaffected. Elemental traits (carbon, nitrogen), chemical defences (phenolics) and tissue bleaching of both seaweeds were generally unaffected by temperature. Effects of warming and MHWs on seaweed holobionts (host plus its microbiota) are likely species‐specific. The effect of increased temperature on Ecklonia's microbiota and subsequent increased consumption suggest that changes to kelp microbiota may underpin kelp‐herbivore interactions, providing novel insights into potential mechanisms driving change in species' interactions in warming oceans.
Genetic architecture of ecological divergence between Oryza rufipogon and Oryza nivara
Authors: Meng Qing‐Lin , Qiang Cheng‐Gen , Li Ji‐Long , Geng Mu‐Fan , Ren Ning‐Ning , Cai Zhe , Wang Mei‐Xia , Jiao Zi‐Hui , Zhang Fu‐Min , Song Xian‐Jun , Ge Song 
Published: January 2024

AbstractEcological divergence due to habitat difference plays a prominent role in the formation of new species, but the genetic architecture during ecological speciation and the mechanism underlying phenotypic divergence remain less understood. Two wild ancestors of rice (Oryza rufipogon and Oryza nivara) are a progenitor‐derivative species pair with ecological divergence and provide a unique system for studying ecological adaptation/speciation. Here, we constructed a high‐resolution linkage map and conducted a quantitative trait locus (QTL) analysis of 19 phenotypic traits using an F2 population generated from a cross between the two Oryza species. We identified 113 QTLs associated with interspecific divergence of 16 quantitative traits, with effect sizes ranging from 1.61% to 34.1% in terms of the percentage of variation explained (PVE). The distribution of effect sizes of QTLs followed a negative exponential, suggesting that a few genes of large effect and many genes of small effect were responsible for the phenotypic divergence. We observed 18 clusters of QTLs (QTL hotspots) on 11 chromosomes, significantly more than that expected by chance, demonstrating the importance of coinheritance of loci/genes in ecological adaptation/speciation. Analysis of effect direction and v‐test statistics revealed that interspecific differentiation of most traits was driven by divergent natural selection, supporting the argument that ecological adaptation/speciation would proceed rapidly under coordinated selection on multiple traits. Our findings provide new insights into the understanding of genetic architecture of ecological adaptation and speciation in plants and help effective manipulation of specific genes or gene cluster in rice breeding.
An evaluation of intensive care nurses' performance of indirect calorimetry measurements
Authors: Occhiali Emilie , Bernard Benedicte , Fraboulet Marion , Achamrah Najate , Clavier Thomas 
Published: January 2024

AbstractBackgroundIndirect calorimetry (IC) is the gold standard to monitor energy expenditure in critically ill patients. In several intensive care units (ICUs), nurses are responsible for carrying out the measurements.AimThe aim of this study was to assess nurses' perception of their involvement in IC.Study designThis was a prospective survey conducted in the surgical ICU of a French university hospital after 18 months of use of the Q‐NRG + ® calorimeter (COSMED©, Italy). All nurses who have used the calorimeter in the previous 6 months in this ICU were questioned through a questionnaire about their theoretical and practical knowledge and experience in using it.ResultsThe participation rate was 93% (28/30 surveyed). All the respondents understood the objectives of performing an IC and 23 of them (82%) had used the device at least once in the previous 6 months. All the users thought it was pertinent that ICU nurses were in charge of the IC measurements, 16 of them (70%) reported having been formally trained, mostly by a colleague, and 17 (77%) felt comfortable with the device after 2 to 5 uses. The five non‐users (8%) did not have the opportunity to do so. Theoretical and practical knowledge could be improved as only 5 of the users (22%) declared to know the main criteria of reliability of the IC measurement and 4 of them (18%) declared to know the maintenance and cleaning protocol of the device.ConclusionNurses quickly felt comfortable with the Q‐NRG + ® in this ICU. Formal initial and ongoing training of all staff completing IC is essential to perform IC measurements safely and to obtain reliable and interpretable results in practice.Relevance to Clinical PracticeInvolving the nursing team in nutritional care, even if it is technical, seems to bring satisfaction in terms of overall patient care.
Perceived barriers of family‐centred care in neonatal intensive care units: A qualitative study
Authors: Abukari Alhassan Sibdow , Schmollgruber Shelley 
Published: January 2024

AbstractBackgroundFamily‐centered care (FCC) approach in neonatal intensive care units (NICUs) has been shown to improve family satisfaction and quality of care. However, several contextual barriers influence its use in NICUs, and these barriers are understudied in Ghana.AimTo describe FCC practice in Ghanaian NICUs in order to understand the contextual barriers.Study DesignThe study employed a descriptive qualitative design. The researchers used a structured interview guide to collect the data in 24 interviews and 12 focus group discussions. We engaged families (n = 42), nurses and midwives (n = 33), and doctors (n = 9) to describe their perspectives on the barriers to FCC in two public tertiary hospital NICUs. The data were mapped, triangulated, and aggregated to inform the findings. Thematic analysis and MAXQDA qualitative software version 2020 were employed to analyse the data. This qualitative study followed the COREQ guidelines and checklist.ResultsPerceived family barriers and perceived facility barriers to FCC were the two main themes. The perceived family barriers include family stress and anxiety, inadequate information sharing and education, culture and religion. The perceived facility barriers are inadequate space and logistics, workload and inadequate staff, restricted entry, and negative staff attitudes.ConclusionThe findings of this study shed light on the barriers to FCC practice in neonatal care in Ghanaian NICUs. Family stress and anxiety, a lack of information sharing, cultures and religious beliefs, NICU workload and staffing shortages, restrictions on family entry into NICUs, and staff attitudes towards families are all contextual barriers to FCC practice.Relevance to Clinical PracticeHealth facility managers and NICU staff may consider addressing these barriers to implement FCC in the NICU in order to enhance family satisfaction and quality neonatal care. The design of future NICUs should consider family comfort zones and subunits to accommodate families and their sick infants for optimal health care outcomes. The development of communication models and guidelines for respectful NICU care may aid in integrating families into ICUs and promoting quality health care outcomes.