bluuebunny/crossref_metadata_2025_split huggingface dataset:
Synthesis of Novel Amino Acids and Dehydroamino Acids Containing the Benzo[b]thiophene Moiety
Authors: Abreu Ana S. , Silva Natália O. , Ferreira Paula M. T. , Queiroz Maria‐João R. P. 
Published: March 2003

AbstractSeveral novel amino acids and dehydroamino acids containing the benzo[b]thiophene moiety were prepared by Michael addition or sequential Michael addition and palladium‐catalyzed C−C or C−N cross couplings. The substrates for Michael addition were the methyl esters of N,N‐bis(tert‐butyloxycarbonyl)dehydroalanine [Boc2−ΔAla−OMe] and N‐(4‐toluenesulfonyl)‐N‐(tert‐butyloxycarbonyl)dehydroalanine [Tos−ΔAla(N‐Boc)−OMe], and the nucleophiles were aromatic thiols and 3‐iodobenzylamine. The addition of mercaptobenzo[b]thiophenes directly to Tos−ΔAla(N‐Boc)−OMe gave stereoselectively, in good yields, the E‐isomer of the corresponding dehydrocysteine. When thiophenols and 3‐iodobenzylamine were used as nucleophiles the presence of an additional function (halogen or amine) allowed a subsequent palladium‐catalyzed cross‐coupling reaction with functionalized benzo[b]thiophenes (boronic acids, a halogen or an amine). Using this strategy, several racemic amino acid and dehydroamino acid derivatives, which are linked to the benzo[b]thiophene moiety by an aromatic spacer, were obtained in good yields. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
Recommendable Routes to Trifluoromethyl‐Substituted Pyridine‐ and Quinolinecarboxylic Acids
Authors: Cottet Fabrice , Marull Marc , Lefebvre Olivier , Schlosser Manfred 
Published: March 2003

AbstractAs part of a case study, rational strategies for the preparation of all ten 2‐, 3‐, or 4‐pyridinecarboxylic acids and all nine 2‐, 3‐, 4‐, or 8‐quinolinecarboxylic acids bearing trifluoromethyl substituents at the 2‐, 3‐, or 4‐position were elaborated. The trifluoromethyl group, if not already present in the precursor, was introduced either by the deoxygenative fluorination of suitable carboxylic acids with sulfur tetrafluoride or by the displacement of ring‐bound bromine or iodine by trifluoromethylcopper generated in situ. The carboxy function was produced by treatment of organolithium or organomagnesium intermediates, products of halogen/metal or hydrogen/metal permutation, with carbon dioxide. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
Selective and Efficient Structural Elaboration of 2‐(Trifluoromethyl)quinolinones
Authors: Marull Marc , Schlosser Manfred 
Published: March 2003

AbstractThe acid‐catalyzed cyclization‐condensation between anilines and ethyl 4,4,4‐trifluoroacetoacetate affords 1,4‐dihydro‐2‐trifluoromethyl‐4H‐4‐quinolinones (1), which can easily be converted into 4‐bromo‐2‐(trifluoromethyl)quinolines. These undergo halogen/metal exchange, generating 2‐trifluoromethyl‐4‐quinolyllithiums, when treated with butyllithium, and hydrogen/metal exchange, generating 4‐bromo‐2‐trifluoromethyl‐3‐quinolyllithiums, when treated with lithium diisopropylamide. Trapping of the latter intermediates provides 3‐functionalized products that may be further elaborated by electrophilic substitution of the bromine atom. A few unexpected findings resulted from these investigations, the most noteworthy being an unprecedented buttressing effect and a counterintuitive halogen reactivity. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003)
Continuous Xylitol Production from Synthetic Xylose Solutions by Candida guilliermondii: Influence of pH and Temperature
Authors: Converti A. , Torre P. , De Luca E. , Perego P. , Del Borghi M. , da Silva S.S. 
Published: March 2003

AbstractThe effects of pH and temperature on continuous xylitol production by Candida guilliermondii have been studied under semiaerobic conditions. The specific productivites obtained at different pH have been used in the model proposed by Villadsen et al. with the aim to get information on the enzyme likely limiting xylitol production (xylose reductase). The kinetic results obtained at different temperatures have been utilized to estimate the thermodynamic parameters either of the reduction of xylose to xylitol (ΔH# = 62 kJ mol–1; ΔS# = –0.12 kJ mol–1 K–1) or of the biocatalyst thermal inactivation (ΔHD° = 90 kJ mol–1; ΔSD° = 0.30 kJ mol–1 K–1). Finally, the well‐known empirical procedure of Sizer has been compared with the so‐called “thermodynamic approach” from the viewpoint of their ability to explain the physical meaning of the related thermodynamic parameters.
Studies on organoleptic properties of food products from fresh egg and egg powder through principal component analysis
Authors: Chauhan Valentina Singh , Sharma Alka 
Published: March 2003

AbstractThe population which is below the poverty line is devoid of nutritious diet. Egg and milk are categorized as complete foods. The defensive organizations are situated in such remote places where fresh food material is not available. Keeping in view these problems, the study of organoleptic variables, viz., color, appearance, aroma, texture and taste in the food products of cake, omelet doughnut, coconut macaroon and mayonnaise from fresh egg and egg powder, was conducted. Principal component analysis was carried out. Organoleptic properties of doughnut prepared from egg powder were superior compared to fresh egg which had better sensory traits for coconut macaroon. The sensory traits like taste, texture and aroma were the most influential traits studied to pronouncing as a panel decision. It is proposed that fresh egg and egg powder should be preferred in the process of preparation of coconut macaroon and doughnut, respectively.
Use of starch/xanthan gum combinations as thickeners of cocoa syrups
Authors: Sikora Marek , Juszczak Lesław , Sady Marek , Krawontka Jan 
Published: March 2003

AbstractThe influence of starch‐xanthan thickening systems on the sensory, textural and rheological properties of cocoa syrups was studied. The results of whole and partial sensory analyses of syrups obtained under laboratory conditions were presented and compared to those of commercially available syrups. In the evaluation of texture such parameters as hardness, adhesiveness, cohesiveness, gumminess and stringiness were considered. The results of rheological measurements were presented in the form of flow curves as well as viscosity/time and viscosity/temperature relationships. Flow curves were fitted to the models of Ostwald‐de Waele and Casson, which allowed characterising the syrups under study to non‐Newtonian, pseudoplastic, and thixotropic fluids. It was concluded that the quantity of thickeners used influenced not only rheological, but also textural and sensory properties of the syrups. The decrease of pseudoplasticity and hardness with an increase of xanthan addition was a result of high sugars level in the syrups. This phenomenon was a result of competition between sugars (mono‐, di‐, and oligosaccharides) and hydrocolloids for water molecules in the systems under study.
Nutritional value of broad bean seeds. Part 1: Starch and fibre
Authors: Giczewska Anna , Borowska Julitta 
Published: March 2003

AbstractThis paper characterizes starch and dietary fibre in the seeds of fine‐size and large‐size seed varieties of broad bean and in edible varieties of pea for comparison. The experimental material included seeds at full physiological maturity. The fine‐size seed varieties of broad bean, Gobik and Goral, contained slightly less total starch (62.32% and 62.19% of dry matter) than the large‐size seed varieties, Windsor Bialy and Bartom (65.32% and 65.26% of dry matter). It was shown that fine‐size seed varieties of broad bean are a good source of resistant starch, which is comparable to large‐size seed varieties. As far as the content of total starch is concerned, the share of this form of starch in broad bean seeds amounted to 1/3. Digestible starch in broad beans was in the range of 39–42% of dry matter, pea contained approximately one half less starch of this type. Moreover, it was found that the relation of rapidly digestible starch to slowly digestible starch amounted to 1 : 1 irrespective of broad bean variety. Dietary fibre in broad beans was in the range of 20.36%–26.79% of dry matter while half of it was found to be concentrated in the seed coat. The soluble fraction of the total content of fibre amounted to 11.81% in the Bartom variety and up to 15.89% in the Gobik variety.
Nutritional value of broad bean seeds. Part 2: Selected biologically active components
Authors: Borowska Julitta , Giczewska Anna , Zadernowski Ryszard 
Published: March 2003

AbstractSelected biologically active non‐nutrient components (BANS) were determined in broad bean seeds of fine‐size and large‐size seed varieties and in pea seeds for comparison. Among the analysed biologically active substances the broad bean seeds of fine‐size and large‐size seed varieties were differentiated mainly by phenolic compounds (including flavanols and proantocyanidines) which appear in twice as large quantities in large‐size seed varieties. It was shown that in comparison to pea, broad bean seeds are characterised by a higher content of phenolic compounds, phytates as well as a higher activity of inhibitors of trypsin and amylases. Moreover, it was found that phenolic compounds accumulate mainly in the dark‐colored seed coats of large‐size broad bean and this fact is related to higher activity inhibiting α‐amylases of methanol extracts from this fraction of seeds.
Unexpected condensation reaction of two units of 1,2‐dihydrophosphinine 1‐oxides in the presence of tetracyanoethylene
Authors: Keglevich György , Kovács János , Szöllősy Áron , Kovács Attila , Szabó Andrea , Ludányi Krisztina , Kádas István , Tőke László 
Published: March 2003

AbstractIn the presence of tetracyanoethylene, the reaction of two molecules of dihydrophosphinine oxide 2B followed an unexpected route to afford diphosphatricyclododecatrienes 4 instead of the corresponding Diels–Alder cycloadducts (3). Structures of the products (4) have been elucidated by a joint application of spectroscopy and quantum chemical calculations. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:29–35, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10062
One‐step transformation of ammonium dialkyl phosphoroselenoates into dialkyl phosphoramidates
Authors: Mielniczak Grażyna , Łopusiński Andrzej 
Published: March 2003

AbstractAmmonium dialkyl phosphoroselenoates are directly converted into the dialkyl phosphoramidates by iodosobenzene and iodoxybenzene. The inversion of configuration at the phosphorus atom, using model diastereoisomeric ammonium cis‐ and trans‐2‐oxo‐2‐seleno‐4‐methyl‐1,3,2‐dioxaphosphinan system, was observed. The mechanistic scheme of this transformation is discussed. © 2003 Wiley Periodicals, Inc. Heteroatom Chem 14:121–127, 2003; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.10110
Photochromic Properties of New Benzoindene‐Fused 2H‐Chromenes
Authors: Martins Cristina I. , Coelho Paulo J. , Carvalho Luis M. , Oliveira‐Campos Ana M. F. , Samat André , Guglielmetti Robert 
Published: March 2003

AbstractThe synthesis and the photochromic properties of new photochromic 6,7‐ and 7,8‐benzoindene annellated benzopyrans are described. When compared to parent indeno‐fused 2H‐chromenes (2H‐[1]benzopyrans), compounds 10 and 12 exhibit a significant bathochromic shift of maximum‐absorption wavelength, an increase in the colorability, and similar fading rates.
Designing Novel Contrast Agents for Magnetic Resonance Imaging. Synthesis and Relaxometric Characterization of three Gadolinium(III) Complexes Based on Functionalized Pyridine‐Containing Macrocyclic Ligands
Authors: Aime Silvio , Gianolio Eliana , Corpillo Davide , Cavallotti Camilla , Palmisano Giovanni , Sisti Massimo , Giovenzana Giovanni B. , Pagliarin Roberto 
Published: March 2003

AbstractThe three novel pyridine‐containing 12‐membered macrocyclic ligands 1–3 were synthesized. The coordinating arms are represented by three acetate moieties in 1 and 3 and by one acetate and two phosphonate moieties in 2. In all three ligands, the acetate arm in the distal position is substituted, with a benzyl group in 1 and 2 and with an arylmethyl moiety in 3. The relaxivities r1p (20 MHz, 25°) of GdIII complexes are: GD⋅1, r1p=8.3 mM−1 s−1; GD⋅2, r1p8.1 mM−1 s−1; Gd⋅3, r1p10.5 mM−1 s−1. 1H‐NMRD and 17O‐NMR T2 data show that Gd⋅1 and Gd⋅3 contain two H2O molecules in the inner sphere, whereas the presence of two phosphonate arms allows the coordination of only one H2O molecule in Gd⋅2. Interestingly, the exchange lifetime of coordinated H2O in the three complexes is similar in spite of the difference in the coordination number of the GdIII ion (i.e., 9 in Gd⋅1 and Gd⋅3, and 8 in Gd⋅2). 1H‐Relaxometric measurements at different pH and in the presence of lactate and oxalate were carried out to get some insight into the formation of ternary complexes from Gd⋅1 and Gd⋅3. Finally, it was found that binding to human‐serum albumin (HSA) of Gd⋅1 and Gd⋅2, though weak, yields limited relaxivity enhancements, likely as a consequence of effects on the hydration sphere caused by donor atoms on the surface of the protein.
Studies on the Stereoselective Synthesis of Deuterated D‐Ribose Derivatives
Authors: Kundu Mrinal K. , Földesi Andras , Chattopadhyaya Jyoti 
Published: March 2003

AbstractIn view of the importance of the site‐specific substitution of the H‐atom by its stable isotope 2H in a stereoselective/stereospecific manner at the pentose sugar residue, decreasing the spectral overcrowding in various regions of 1D and 2D homo‐ and heteronuclear correlation spectra of oligo‐DNA and ‐RNA, there is always a need for the development of new methods for the incorporation of 2H at different sites of a ribose. High‐yielding multistep syntheses of C(2)‐, and (5R)‐ and (5S)‐3,5‐deuterated ribose derivatives have been envisaged for the application of site‐specific incorporation of multilabeled nucleosides into oligomers to facilitate their structure elucidation by NMR spectroscopy. All syntheses started from D‐glucose after proper derivatization. In the case of C(2), >97 atom‐% isotope was incorporated, employing an inversion of the configuration at C(2) as the key reaction. For C(5), two different routes were envisaged: on the one hand, deuterated achiral reagent was treated with a conformationally locked sugar moiety 15, while, on the other, chiral protonated sources were used to transfer the H‐atom to a C(5)‐deuterated aldehyde 18. In all cases, enantiomeric and isotopic purities were found to be as high as >97% as determined by NMR spectroscopy.
An Efficient Synthesis of 3′‐Amino‐3′‐deoxyguanosine from Guanosine
Authors: Zhang Lei , Cui Zhiyong , Zhang Biliang 
Published: March 2003

Abstract3′‐Amino‐3′‐deoxyguanosine was synthesized from guanosine in eight steps and 58% overall yield. The 2′,3′‐diol of 5′‐O‐[(tert‐butyl)diphenylsilyl]‐2‐N‐[(dimethylamino)methylidene]guanosine was reacted with α‐acetoxyisobutyryl bromide and treated with 0.5n NH3 in MeOH to yield 9‐{2′‐O‐acetyl‐3′‐bromo‐5′‐O‐[(tert‐butyl)diphenylsilyl]‐3′‐deoxy‐β‐D‐xylofuranosyl]‐2‐N‐[(dimethylamino)methylidene]guanine, which was reacted with benzyl isocyanate, NaH, and then 3.0n NaOH, and finally with Pd/C (10%) and HCO2NH4 in EtOH/AcOH to afford 3′‐amino‐3′‐deoxyguanosine.
Structural Diversity in Thallium Chemistry. Part V
Authors: Linden Anthony , Petridis Alexander , James Bruce D. 
Published: March 2003

AbstractFrom thallium(III) bromide solution, the unsubstituted pyridinium cation yields a complex (1) with the [Tl2Br9]3− anionic stoichiometry. The Raman spectrum and single‐crystal X‐ray crystallographic analysis showed that the salt contains independent [TlBr4]− and bromide anions. A variety of mono‐ and disubstituted pyridinium cations were also employed in similar syntheses. The 2‐bromopyridinium cation gave a salt 2 with [TlBr5]2− stoichiometry, but the crystal structure revealed very weakly interacting [TlBr4]− and bromide anions with a Tl ⋅⋅⋅Br− distance of 4.1545(6) Å. The 2‐(ammoniomethyl)pyridinium and 2‐amino‐4‐methylpyridinium cations yielded complexes containing [TlBr5]2− (3) and [TlBr4]− (4) species, respectively, which were confirmed by Raman spectroscopy and X‐ray crystallographic analyses. For 3, the [TlBr5]2− anion has a highly distorted trigonal bipyramidal conformation with one long axial Tl ⋅⋅⋅Br bond of 3.400(2) Å. Microanalytical results in conjunction with Raman spectra from a further five salts confirmed that they all contain the simple [TlBr4]− anion. NH ⋅⋅⋅Br Hydrogen bonds clearly influence the nature of the anionic species obtained in these systems.
‘Oligomere' Kondensationsprodukte von (1E,3E,5E)‐1,6‐Di(2‐furyl)hexa‐1,3,5‐trien mit Acetaldehyd: Tetrahydro‐tetramethyl‐octaepoxy[60]annulen(6.1.6.1.6.1.6.1)
Authors: Märkl Gottfried , Ehrl Robert , Kreitmeier Peter 
Published: March 2003

AbstractOligomeric Condensation Products of (1E,3E,5E)‐1,6‐Di(2‐furyl)hexa‐1,3,5‐triene with Acetaldehyde: Tetrahydro‐tetramethyl‐octaepoxy[60]annulene(6.1.6.1.6.1.6.1)The Ca(NO3)2‐induced condensation of (1E,3E,5E)‐1,6‐di(2‐furyl)hexa‐1,3,5‐triene (6) with acetaldehyde yields the linear ‘oligomers' 7–11 with 2–6 1,6‐di(2‐furyl)hexa‐1,3,5‐triene units and 1–4 acetaldehyde units, besides a cyclic condensation product 12 obtained from 4 equiv. of 6 with 4 equiv. of acetaldehyde. According to spectroscopic studies, 12 is the tetrahydro‐tetramethyl‐octaepoxy[60]annulene(6.1.6.1.6.1.6.1) as the most expanded annulene system known so far. While the dehydrogenation of 12 to give the tetramethyl‐octaepoxy[60]annulene(6.1.6.1.6.1.6.1) cannot be achieved, the oxidation of 12 with Br2 yields a black, in all organic solvents nearly insoluble solid 14, which possibly is the tetramethyl‐octaepoxy[58]annulene(6.1.6.1.6.1.6.1) dication. Because of the insolubility of 14, unfortunately most of its spectroscopic data are not available. However, the λmax values in the UV/VIS/NIR spectrum of 14 (Soret and Q bands) are in line with the values of the tetraepoxy[26]annulene(4.2.4.2) dication, the tetraepoxy[30]annulene(4.4.4.4) dication, and the tetraepoxy[34]annulene(6.4.6.4) dication.
Two Novel ent‐Kaurene Diterpenoids from Isodon rubescens
Authors: Han Quan‐Bin , Jiang Bei , Zhang Ji‐Xia , Niu Xue‐Mei , Sun Han‐Dong 
Published: March 2003

AbstractA novel 20‐nor‐ent‐kaurene diterpenoid, rubescensin N (1), and a new 7,20‐epoxy‐ent‐kaurene diterpenoid, rubescensin O (2), along with the seven known diterpenoids rabdoternins A–F and xerophilusin N, were isolated from Isodon rubescens collected in Jiyuan prefecture, Henan Province, China. Their structures were established by extensive spectroscopic analysis. Compound 1 is the first example of a naturally occurring 20‐nor‐ent‐kaurene diterpenoid from the Isodon genus plants.
Pseudolarolides O and P, Two Novel Triterpene Dilactones from Pseudolarix kaempferi
Authors: Chen Guo‐Fu , Tan Chang‐Heng , Li Zhu‐Lian , Jiang Shan‐Hao , Zhu Da‐Yuan 
Published: March 2003

AbstractPseudolarolides O (1) and P (2), two novel triterpenoids with a cycloartane‐type framework, were isolated from the seeds of Pseudolarix kaempferi Gord. (Pinaceae). Their structures were elucidated as (16R,23S,25R)‐16,23‐epoxy‐3,4 : 9,10‐disecocycloartan‐1(10),9(11)‐diene‐3(4),26(23)‐diolide (1), and (9S,16R,23S,25R)‐1,9 : 16,23‐diepoxy‐8,9 : 9,10‐disecocycloartan‐1(29),5(6),10(19)‐triene‐3(4),26(23)‐diolide (2), respectively, on the basis of spectroscopic techniques and X‐ray‐diffraction studies.
The 14‐Alkyl‐ and 14‐Alkenyl‐5β‐methylindolomorphinan Series Provide δ‐Selective Partial Opioid Agonists
Authors: Grundt Peter , Martinez‐Bermejo Fernando , Lewis John W. , Husbands Stephen M. 
Published: March 2003

AbstractA series of 14β‐alkyl‐ and 14β‐alkenyl‐5β‐methylindolomorphinans was synthesized and evaluated in opioid binding and functional assays. While being relatively nonselective in binding assays, the 14‐cinnamyl and 14‐isopentyl members showed selective opioid δ‐receptor partial agonist activity in [35S]GTPγS assays.
The Composition of Keto Aldoses in Aqueous Solution as Determined by NMR Spectroscopy
Authors: Köpper Sabine , Freimund Stefan 
Published: March 2003

AbstractKeto aldoses usually form complex mixtures of equilibrating isomers in solution. This is due to the two different positions that may be used for ring closure in dicarbonyl sugars. The composition of various 2‐keto aldoses 1–5 and 8, the 3‐keto aldose 2‐deoxy‐D‐erythro‐hexos‐3‐ulose (9), and the ketose 1‐deoxy‐D‐ribulose (10) in aqueous solution has been determined by NMR spectroscopy. The investigated keto aldoses form equilibria containing three to fifteen isomers. Among various furanose and pyranose ring structures stemming from 1,4‐, 1,5‐, 2,5‐, and 2,6‐cyclization, bicyclic forms were also found in several cases. The 2‐keto aldoses mainly exist as hydrated isomers in H2O. Therefore, these forms and their proportions were compared to forms found in two homomorphous aldoses and one homomorphous ketose as model compounds. Besides the NMR data, also the composition of the 2‐keto aldoses agreed with the average of forms found in the model compounds, a finding that might eventually be useful for deducing the composition of other keto aldoses.
Nonenzymatic Oligomerization of Ribonucleotides: Towards in vitro Selection Experiments
Authors: Hey Marcus , Hartel Christian , Göbel Michael W. 
Published: March 2003

AbstractInspired by the polymerase chain reaction, orthogonal primer–template pairs have been applied in template‐controlled oligomerization experiments with Orgel's imidazole‐activated ribonucleotide‐5′‐phosphates. Variation of the linker length allowed us to monitor the extension of both primers simultaneously on a DNA sequencer. Sets of hexapyrimidine primers were found that are capable of inducing the reciprocal synthesis of each other's binding site. Considerable cross‐inhibition by different monomers was observed. However, this effect is a function of primer sequence and can disappear in favorable cases. With random sequences introduced into the templates, selection experiments are within reach. First results are reported below.
Photochemical Synthesis of Highly Functionalized Cyclopropyl Ketones
Authors: Wessig Pablo , Mühling Olaf 
Published: March 2003

AbstractA series of di‐ and trisubstituted cyclopropyl ketones 11 were prepared by irradiation of ketones 3 and 5, which bear a leaving group adjacent to the carbonyl C‐atom. The required ketones 3 could be easily synthesized either by functionalization of ketones 1 with a hypervalent iodine reagent, 2, or by O‐sulfonylation of α‐hydroxy ketones 7. The nitrates 5 were obtained by treatment of the corresponding α‐bromo ketones with AgNO3. The irradiation of 3 and 5 must be performed in the presence of an acid scavenger (1‐methyl‐1H‐imidazole) to obtain the cyclopropanes 11 in good yields. The synthetic efficiency of the method was, among other things, demonstrated by the preparation of a highly strained bicyclo[2.1.0]pentane 11i in good yield. The mechanism of the photochemical cyclization was investigated by means of photokinetic measurements, as well as by quantum‐chemical calculations. It was shown that the presence of the leaving group substantially influences all steps of the photochemical reaction cascade. The X‐ray crystal structures of 11j and exo‐11k were also determined.
Acceleration of the Baylis–Hillman Reaction in the Presence of Ionic Liquids
Authors: Kim Eun Jin , Ko Soo Y. , Song Choong Eui 
Published: March 2003

AbstractThe Baylis–Hillman reaction is accelerated in the presence of ionic liquids. Of various 1‐butyl‐3‐methylimidazolium (bmim)‐based ionic liquids tested, [bmim][PF6] has been found to result in the highest rate increase. In the company of Lewis acid and H‐bond‐donor additives, the reaction rates further improve, albeit only modestly. A preparatively useful Baylis–Hillman procedure prescribes the use of [bmim][PF6] with La(OTf)3 and 2,2′2″‐nitrilotris[ethanol], in which the net effect of the ionic liquid is to bring about a more than twofold rate increase over the otherwise same reaction in MeCN.