bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Kualitas Pelayanan Kesehatan Terhadap Kepuasan Pasien Rawat Jalan Peserta BPJS Di Puskesmas Antang Perumnas Kota Makassar
Authors: Hartia Ningsih Sri Mutmainna , Haeruddin  , Andi Multazam  
Published: February 2024

Di era globalisisasi ini, yang mejadi indikator keberhasilan pelayanan kesehatan di puskesmas adalah kepuasan pasien. Kualitas layanan akan menjadi tuntutan masyarakat bagi penyedian layanan jasa yang berorientasi profit maupun nonprofit. Dapat dilihat bagaimana kualitas layanan menjadi tuntutan masyarakat yang menyampaikan ketidakpuasan mereka terhadap unjuk kerja suatu instansi yang menyediakan layanan jasa yang berhubungan langsung terhadap masyarakat yang berkaitan dengan pelayanan kesehatan. Jenis penelitian ini merupakan penelitian kuantitatif dengan pendekatan Cross Sectional Study. Dengan jumlah sampel dalam penelitian ini yaitu sebanyak 100 pasien. Menggunakan anaslis uji univariat, uji bivariat, regerasi linear berganda dan multivariat. Hasil penelitian ini menujukkan bahwa tingkat kepuasan pasien di instalasi rawat jalan peserta BPJS di Puskesmas Antang Perumnas Kota Makassar sudah baik dan puas. Hal ini dapat kita lihat dari hasil uji statistk yang menunjukkan bahwa secara parsial variabel bukti fisik (tangible), kehandalan (reliability), dan empati (empathy) berpengaruh positif dan signifikan terhadap kepuasan pasien dengan nilai signifikan yang berada bawah 0,05 dan nilai T hitung > T table. Secara simultan variabel bukti fisik (tangible), kehandalan (reliability), ketanggapan (responsiveness), empati (empathy), dan jamninan (assurance) berpengaruh positif dan signifikan terhadap kepuasan pasien. Diharapkan pada pihak puskesmas untuk selalu memantau dan menganalisis setiap keluhaan dan harapan pasien yang berkaitan dengan kepuasan pasien rawat jalan peserta BPJS di Puuskesmas Antang Perumnas Kota Makassar.
Una «Gelegenheittsammlung» catalana del canzoniere R (BnF, fr. 22543)?
Authors: Menichetti Caterina 
Published: February 2024

RIASSUNTO: L’articolo esamina la serie finale della sezione R2 dello Chansonnier d’Urfé (R_162-R_193). Combinando l’analisi dell’epoca e dei contesti di produzione delle liriche; l’esame della loro tradizione manoscritta; e lo studio delle tecniche di compilazione del canzoniere C, parallelo di R, si avanza l’ipotesi che la sezione R2 sia debitrice di una raccolta d’occasione assemblata a ridosso del 1250, e particolarmente esposta a materiali di ascendenza catalana e a testi di ambiente italiano di argomento latamente «imperiale».
ABSTRACT: The article is devoted to the final part of the Chansonnier d’Urfé section called R2 (R_162-R_193). Managing the analysis of the time and contexts of production of the poems; the examination of their manuscript tradition; and the study of the compilation techniques of songbook C, the hypothesis is put forward that R2 is indebted to a collection assembled around 1250, and exposed to material of Catalan ascendancy and to texts of Italian origin of «imperial» setting.
Modernizacja sądownictwa powszechnego w Polsce w okresie pandemii COVID-19
Authors: Piekarski Krzysztof 
Published: February 2024

Przedmiotem niniejszej pracy jest polityka sądownictwa powszechnego w Polsce i działania podejmowane w jej obrębie w okresie pandemii COVID-19. Autor omawia proces modernizacji w sądownictwie oraz przywołuje porównawcze przykłady zagraniczne. Przedstawia propozycje i wdrożone projekty mające na celu unowocześnienie sądownictwa, ze szczególnym uwzględnieniem informatyzacji. Stawia tezę, że sytuacja wywołana pandemią COVID-19 w znacznym stopniu przyśpieszyła wprowadzenie narzędzi umożliwiających dostęp online do sądów w Polsce. Niektóre rozwiązania zostały przyjęte przez ustawodawcę jedynie z myślą o czasach epidemii, inne w zamiarze prawodawcy miały na stałe stać się częścią procedur sądowych.
Efficacy of Bath PUVA in the treatment of Palmoplantar hyperkeratosis
Authors: Ahmed Md Iqbal , Hoq Abu Jafar Md Shahidul , Alam AKM Mahbubul , Ahamed Abu Reza Sayem , Snigdha Kaniz Shahali Reza , Hamid Md Abdul , Sayem Abu Sayed 
Published: February 2024

Background: Palmoplantar hyperkeratosis, or palmoplantar keratoderma, is a combination of skin conditions that are characterized by excessive thickening of the skin, mainly on the soles and palms. There are various treatment methods for keratoderma, and one of those methods are treatment through bathwater PUVA. It is a type of photochemotherapy.
Objective of the study: The aim of the study was to observe the efficacy of bath PUVA treatment for palmoplantar hyperkeratosis.
Methodology: This randomized clinical trial study was conducted at the Department of Dermatology and Venereology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh. The study duration was 6 months, from September 2007 to February 2008. A total of 30 patients presented with with palmoplantar hyperkeratosis were enrolled in this study through random sampling method following the inclusion and exclusion criteria.
Results: Majority of participant (33.3%) were from the age group of 31-40 years. The mean ±SD age was 38.40±10.89 years, and the age range of the participants was 20-58 years. 70% of the participants were male, 83.3% were from low socioeconomic class, and 36.7% were businessmen respectively. Histopathological diagnosis revealed that 52% patients had psoriasis, 33% had nonspecific dermatitis, and 10% patients had chronic inflammatory dermatitis. Gradual improvement was observed from baseline to 8 weeks follow-up in regards to palmoplantar surface area involvement, erythema, and hyperkeratosis. 46.7% of the participants reported skin tenderness, and 93.3% have a burning sensation and no other side effects.
Conclusion: Bath PUVA may be an effective option in the treatment palmoplantar keratosis particularly of psoriatic patients. A mild form of nonspecific dermatitis may be treated with bath PUVA.
Mugda Med Coll J. 2022; 5(2): 76-81
Khalouta transform and applications to Caputo-fractional differential equations
Authors: Kumawat Nikita , Shukla Akanksha , Mishra Manvendra Narayan , Sharma Rahul , Dubey Ravi Shanker 
Published: February 2024

The paper aims to utilize an integral transform, specifically the Khalouta transform, an abstraction of various integral transforms, to address fractional differential equations using both Riemann-Liouville and Caputo fractional derivative. We discuss some results and the existence of this integral transform. In addition, we also discuss the duality between Shehu transform and Khalouta transform. The numerical examples are provided to confirm the applicability and correctness of the proposed method for solving fractional differential equations.2010 Mathematics ClassificationPrimary 92B05, 92C60; Secondary 26A33.
The loading direction dramatically affects the mechanical properties of the mouse tibia
Authors: Farage-O’Reilly Saira Mary , Cheong Vee San , Pickering Edmund , Pivonka Peter , Bellantuono Ilaria , Kadirkamanathan Visakan , Dall’Ara Enrico 
Published: February 2024

Introduction: The in vivo tibial loading mouse model has been extensively used to evaluate bone adaptation in the tibia after mechanical loading treatment. However, there is a prevailing assumption that the load is applied axially to the tibia. The aim of this in silico study was to evaluate how much the apparent mechanical properties of the mouse tibia are affected by the loading direction, by using a validated micro-finite element (micro-FE) model of mice which have been ovariectomized and exposed to external mechanical loading over a two-week period.Methods: Longitudinal micro-computed tomography (micro-CT) images were taken of the tibiae of eleven ovariectomized mice at ages 18 and 20 weeks. Six of the mice underwent a mechanical loading treatment at age 19 weeks. Micro-FE models were generated, based on the segmented micro-CT images. Three models using unitary loads were linearly combined to simulate a range of loading directions, generated as a function of the angle from the inferior-superior axis (θ, 0°–30° range, 5° steps) and the angle from the anterior-posterior axis (ϕ, 0°: anterior axis, positive anticlockwise, 0°–355° range, 5° steps). The minimum principal strain was calculated and used to estimate the failure load, by linearly scaling the strain until 10% of the nodes reached the critical strain level of −14,420 με. The apparent bone stiffness was calculated as the ratio between the axial applied force and the average displacement along the longitudinal direction, for the loaded nodes.Results: The results demonstrated a high sensitivity of the mouse tibia to the loading direction across all groups and time points. Higher failure loads were found for several loading directions (θ = 10°, ϕ 205°–210°) than for the nominal axial case (θ = 0°, ϕ = 0°), highlighting adaptation of the bone for loading directions far from the nominal axial one.Conclusion: These results suggest that in studies which use mouse tibia, the loading direction can significantly impact the failure load. Thus, the magnitude and direction of the applied load should be well controlled during the experiments.
Influence of various pilot hole profiles on pedicle screw fixation strength in minimally invasive and traditional spinal surgery: a comparative biomechanical study
Authors: Li Yun-Da , Lai Po-Liang , Hsieh Ming-Kai , Chen Weng-Pin , Lee De-Mei , Tsai Tsung-Ting , Tai Ching-Lung 
Published: February 2024

Despite advancements in pedicle screw design and surgical techniques, the standard steps for inserting pedicle screws still need to follow a set of fixed procedures. The first step, known as establishing a pilot hole, also referred to as a pre-drilled hole, is crucial for ensuring screw insertion accuracy. In different surgical approaches, such as minimally invasive or traditional surgery, the method of creating pilot holes varies, resulting in different pilot hole profiles, including variations in size and shape. The aim of this study is to evaluate the biomechanical properties of different pilot hole profiles corresponding to various surgical approaches. Commercially available synthetic L4 vertebrae with a density of 0.16 g/cc were utilized as substitutes for human bone. Four different pilot hole profiles were created using a 3.0 mm cylindrical bone biopsy needle, 3.6 mm cylindrical drill, 3.2–5.0 mm conical drill, and 3.2–5.0 mm conical curette for simulating various minimally invasive and traditional spinal surgeries. Two frequently employed screw shapes, namely, cylindrical and conical, were selected. Following specimen preparation, screw pullout tests were performed using a material test machine, and statistical analysis was applied to compare the mean maximal pullout strength of each configuration. Conical and cylindrical screws in these four pilot hole configurations showed similar trends, with the mean maximal pullout strength ranking from high to low as follows: 3.0 mm cylindrical biopsy needle, 3.6 mm cylindrical drill bit, 3.2–5.0 mm conical curette, and 3.2–5.0 mm conical drill bit. Conical screws generally exhibited a greater mean maximal pullout strength than cylindrical screws in three of the four different pilot hole configurations. In the groups with conical pilot holes, created with a 3.2–5.0 mm drill bit and 3.2–5.0 mm curette, both conical screws exhibited a greater mean maximal pullout strength than did cylindrical screws. The strength of this study lies in its comprehensive comparison of the impact of various pilot hole profiles commonly used in clinical procedures on screw fixation stability, a topic rarely reported in the literature. Our results demonstrated that pilot holes created for minimally invasive surgery using image-guided techniques exhibit superior pullout strength compared to those utilized in traditional surgery. Therefore, we recommend prioritizing minimally invasive surgery when screw implantation is anticipated to be difficult or there is a specific need for stronger screw fixation. When opting for traditional surgery, image-guided methods may help establish smaller pilot holes and increase screw fixation strength.
Fabrication of gelatin-heparin based cartilage models: enhancing spatial complexity through refinement of stiffness properties and oxygen availability
Authors: Lindberg G. , Norberg A. , Soliman B. , Jüngst T. , Lim K. , Hooper G. , Groll J. , Woodfield T. 
Published: February 2024

The intricate nature of native cartilage, characterized by zonal variations in oxygen levels and ECM composition, poses a challenge for existing hydrogel-based tissue models. Consequently, these 3D models often present simplified renditions of the native tissue, failing to fully capture its heterogenous nature. The combined effects of hydrogel components, network properties, and structural designs on cellular responses are often overlooked. In this work, we aim to establish more physiological cartilage models through biofabrication of photopolymerizable allylated-gelatin (GelAGE) and Thiolated Heparin (HepSH) constructs with tailorable matrix stiffness and customized architectures. This involves systematically studying how the native glycosaminoglycan Heparin together with hydrogel stiffness, and oxygen availability within 3D structures influence chondrogenic differentiation and regional heterogeneity. A comprehensive library of 3D hydrogel constructs was successfully developed, encompassing GelAGE-HepSH hydrogels with three distinct stiffness levels: 12, 55 and 121 kPa, and three unique geometries: spheres, discs, and square lattices. In soft GelAGE-HepSH hydrogels, the localization of differentiating cells was observed to be irregular, while stiff hydrogels restricted the overall secretion of ECM components. The medium-stiff hydrogels were found to be most applicable, supporting both uniform tissue formation and maintained shape fidelity. Three different 3D architectures were explored, where biofabrication of smaller GelAGE-HepSH spheres without oxygen gradients induced homogenous, hyaline cartilage tissue formation. Conversely, fabrication of larger constructs (discs and lattices) with oxygen gradients could be utilized to design heterogenous cartilage tissue models. Similarly, temporal oxygen gradients were observed to drive interconnected deposition of glycosaminoglycans (GAGs). Control samples of GelAGE without HepSH did not exhibit any notable changes in chondrogenesis as a function of stiffness, architectures, or oxygen concentrations. Overall, the incorporation of HepSH within GelAGE hydrogels was observed to serve as an amplifier for the biological effects from both stiffness and oxygen cues. In conclusion, fabrication of GelAGE-HepSH constructs designed to impose limitations on oxygen availability induce more zone-specific cartilage tissue alignment. This systematic study of matrix components, network stiffness, and oxygen levels in 3D biofabricated structures contributes to the development of more physiologically relevant cartilage models while further enhancing our overall understanding of cartilage tissue engineering.
Amplitude spectral area of ventricular fibrillation can discriminate survival of patients with out-of-hospital cardiac arrest
Authors: Gentile Francesca Romana , Wik Lars , Isasi Iraia , Baldi Enrico , Aramendi Elisabete , Steen-Hansen Jon Erik , Fasolino Alessandro , Compagnoni Sara , Contri Enrico , Palo Alessandra , Primi Roberto , Bendotti Sara , Currao Alessia , Quilico Federico , Vicini Scajola Luca , Lopiano Clara , Savastano Simone 
Published: February 2024

BackgroundEvidence of the association between AMplitude Spectral Area (AMSA) of ventricular fibrillation and outcome after out-of-hospital cardiac arrest (OHCA) is limited to short-term follow-up. In this study, we assess whether AMSA can stratify the risk of death or poor neurological outcome at 30 days and 1 year after OHCA in patients with an initial shockable rhythm or with an initial non-shockable rhythm converted to a shockable one.MethodsThis is a multicentre retrospective study of prospectively collected data in two European Utstein-based OHCA registries. We included all cases of OHCAs with at least one manual defibrillation. AMSA values were calculated after data extraction from the monitors/defibrillators used in the field by using a 2-s pre-shock electrocardiogram interval. The first detected AMSA value, the maximum value, the average value, and the minimum value were computed, and their outcome prediction accuracy was compared. Multivariable Cox regression models were run for both 30-day and 1-year deaths or poor neurological outcomes. Neurological cerebral performance category 1–2 was considered a good neurological outcome.ResultsOut of the 578 patients included, 494 (85%) died and 10 (2%) had a poor neurological outcome at 30 days. All the AMSA values considered (first value, maximum, average, and minimum) were significantly higher in survivors with good neurological outcome at 30 days. The average AMSA showed the highest area under the receiver operating characteristic curve (0.778, 95% CI: 0.7–0.8, p &lt; 0.001). After correction for confounders, the highest tertiles of average AMSA (T3 and T2) were significantly associated with a lower risk of death or poor neurological outcome compared with T1 both at 30 days (T2: HR 0.6, 95% CI: 0.4–0.9, p = 0.01; T3: HR 0.6, 95% CI: 0.4–0.9, p = 0.02) and at 1 year (T2: HR 0.6, 95% CI: 0.4–0.9, p = 0.01; T3: HR 0.6, 95% CI: 0.4–0.9, p = 0.01). Among survivors at 30 days, a higher AMSA was associated with a lower risk of mortality or poor neurological outcome at 1 year (T3: HR 0.03, 95% CI: 0–0.3, p = 0.02).DiscussionLower AMSA values were significantly and independently associated with the risk of death or poor neurological outcome at 30 days and at 1 year in OHCA patients with either an initial shockable rhythm or a conversion rhythm from non-shockable to shockable. The average AMSA value had the strongest association with prognosis.
Genetic, clinical and imaging implications of a noncompaction phenotype population with preserved ejection fraction
Authors: Grebur Kinga , Mester Balázs , Fekete Bálint András , Kiss Anna Réka , Gregor Zsófia , Horváth Márton , Farkas-Sütő Kristóf , Csonka Katalin , Bödör Csaba , Merkely Béla , Vágó Hajnalka , Szűcs Andrea 
Published: February 2024

IntroductionThe genotype of symptomatic left ventricular noncompaction phenotype (LVNC) subjects with preserved left ventricular ejection fraction (LVEF) and its effect on clinical presentation are less well studied. We aimed to characterize the genetic, cardiac magnetic resonance (CMR) and clinical background, and genotype-phenotype relationship in LVNC with preserved LVEF.MethodsWe included 54 symptomatic LVNC individuals (LVEF: 65 ± 5%) whose samples were analyzed with a 174-gene next-generation sequencing panel and 54 control (C) subjects. The results were evaluated using the criteria of the American College of Medical Genetics and Genomics. Medical data suggesting a higher risk of cardiovascular complications were considered “red flags”.ResultsOf the LVNC population, 24% carried pathogenic or likely pathogenic (P) mutations; 56% carried variants of uncertain significance (VUS); and 20% were free from cardiomyopathy-related mutations. Regarding the CMR parameters, the LVNC and C groups differed significantly, while the three genetic subgroups were comparable. We found a significant relationship between red flags and genotype; furthermore, the number of red flags in a single subject differed significantly among the genetic subgroups (p = 0.002) and correlated with the genotype (r = 0.457, p = 0.01). In 6 out of 7 LVNC subjects diagnosed in childhood, P or VUS mutations were found.DiscussionThe large number of P mutations and the association between red flags and genotype underline the importance of genetic-assisted risk stratification in symptomatic LVNC with preserved LVEF.
Characterizing patient details-related challenges from health information technology-related incident reports from Swedish healthcare
Authors: Jabin Md Shafiqur Rahman , Pan Ding , Nilsson Evalill 
Published: February 2024

IntroductionDespite many benefits offered by Health Information Technology (HIT) systems, new technology brings new and unforeseen risks to healthcare quality and patient safety if they're not properly planned, designed, implemented, and managed. This study examined health information technology-related (HIT) incidents to identify patient details-related issues, their association with contributing factors, and outcomes.MethodsSources of information comprised retrospectively collected incident reports (n = 95) using two sampling methods, i.e., purposive and snowball sampling. The incident reports were analyzed using both the inductive method (thematic analysis) and the deductive approach using an existing framework, i.e., the International Classification for Patient Safety.ResultsThe studies identified 90 incidents with 120 patient details-related issues—categorized as either information-related (48%) or documentation-related (52%) problems; around two-thirds of the 120 issues were characterized by human factors. Of the total sample, 87 contributing factors were identified, of which “medical device/system” (45%) and “documentation” (20%) were the most common contributing factors. Of 90 incidents, more than half (59%) comprised patient-related outcomes—patient inconvenience (47%) and patient harm (12%) and the remaining 41% (n = 37) included staff or organization-related outcomes.DiscussionMore than half of the incidents resulted in patient-related outcomes, namely patient inconvenience and patient harm, including disease risks, severe health deterioration, injury, and even patient death. Incidents associated with patient details can cause deleterious effects; therefore, characterizing them should be a routine part of clinical practice to improve the constantly changing healthcare system.