bluuebunny/crossref_metadata_2025_split huggingface dataset:
Magnetodynamic properties of ultrathin films of Fe$$_{\textbf{3}}$$Sn$$_{\textbf{2}}$$-a topological kagome ferromagnet
Authors: Khan Kacho Imtiyaz Ali , Kumar Akash , Gupta Pankhuri , Yadav Ram Singh , Åkerman Johan , Muduli Pranaba Kishor 
Published: February 2024

AbstractFe$$_3$$

3

Sn$$_{2}$$

2

is a topological kagome ferromagnet that possesses numerous Weyl points close to the Fermi energy, which can manifest various unique transport phenomena such as chiral anomaly, anomalous Hall effect, and giant magnetoresistance. However, the magnetodynamic properties of Fe$$_3$$

3

Sn$$_{2}$$

2

have not yet been explored. Here, we report, for the first time, the measurements of the intrinsic Gilbert damping constant ($$\alpha _\text{int}$$

α
int

), and the effective spin mixing conductance (g$$_\text{eff}^{\uparrow \downarrow }$$

eff

↑
↓

) of Pt/Fe$$_3$$

3

Sn$$_2$$

2

bilayers for Fe$$_3$$

3

Sn$$_{2}$$

2

thicknesses down to 2 nm, for which $$\alpha _\text{int}$$

α
int

is $$(3.8 \pm 0.2) \times 10^{-2}$$

(
3.8
±
0.2
)

×

10

-
2

, and g$$_\text{eff}^{\uparrow \downarrow }$$

eff

↑
↓

is $$(11.7 \pm 0.6)~\text{nm}^{-2}$$

(
11.7
±
0.6
)

nm

-
2

. The films have a high saturation magnetization, $$M_\text{S}=620~\mathrm{emu~cm^{-3}}$$

M
S

=
620

emu

cm

-
3

, and large anomalous Hall coefficient, $$R_\text{S}=4.6\times 10^{-10}~{\Omega ~\rm cm~G^{-1}}$$

R
S

=
4.6
×

10

-
10

Ω

cm

G

-
1

. The large values of g$$_\text{eff}^{\uparrow \downarrow }$$

eff

↑
↓

, together with the topological properties of Fe$$_3$$

3

Sn$$_2$$

2

, make Fe$$_3$$

3

Sn$$_2$$

2

/Pt bilayers useful heterostructures for the study of topological spintronic devices.
No additional stress of sublethal gas supersaturation in a landlocked population of Atlantic salmon (Salmo salar) exposed to environmental acidification
Authors: Höglund Erik , Loland Lifen Zhou , Høgberget Rolf , Skov Peter Vilhelm , Velle Gaute 
Published: February 2024

AbstractThe landlocked Atlantic salmon population “bleke” faces extinction due to environmental acidification (EA) and hydropower expansion in the Norwegian river Otra. Despite of restoration, unexpected mortality has been reported for this population, possibly due to gas bubble trauma (GBT) from gas supersaturation (GSS) downstream of hydroelectric plants, or EA induced aluminum toxicity. In this study, we applied the allostasis concept to investigate interactions between EA and GBT. This concept comprises additive effects of stressors, which can lead to allostatic overload. Stress coping mechanisms become maladaptive in such situations, which can be indicated by an inability to mount a proper cortisol response in fish. Fish were exposed to sublethal levels of simulated EA (SEA), GSS (a total gas pressure; TGP; of 110%) or a combination of these stressors for six days. Effects on allostatic load were subsequently investigated by assessing the cortisol response to an acute stress test. SEA increased cortisol responsiveness and GSS induced clinical signs of GBT, but no interacting effects between GSS and SEA were observed. This suggests that that 110% TGP did not have an additive effect on the allostatic load imposed by SEA.
Effective prime factorization via quantum annealing by modular locally-structured embedding
Authors: Ding Jingwen , Spallitta Giuseppe , Sebastiani Roberto 
Published: February 2024

AbstractThis paper investigates novel techniques to solve prime factorization by quantum annealing (QA). First, we present a very-compact modular encoding of a multiplier circuit into the architecture of current D-Wave QA devices. The key contribution is a compact encoding of a controlled full-adder into an 8-qubit module in the Pegasus topology, which we synthesized using Optimization Modulo Theories. This allows us to encode up to a 21 × 12-bit multiplier (and a 22 × 8-bit one) into the Pegasus 5760-qubit topology of current annealers. To the best of our knowledge, these are the largest factorization problems ever encoded into a quantum annealer. Second, we investigated the problem of actually solving encoded PF problems by running an extensive experimental evaluation on a D-Wave Advantage 4.1 quantum annealer. In the experiments we introduced different approaches to initialize the multiplier qubits and adopted several performance enhancement techniques. Overall, 8,219,999 = 32,749 × 251 was the highest prime product we were able to factorize within the limits of our QPU resources. To the best of our knowledge, this is the largest number which was ever factorized by means of a quantum annealer; also, this is the largest number which was ever factorized by means of any quantum device without relying on external search or preprocessing procedures run on classical computers.
Enhancing SiGeSn nanocrystals SWIR photosensing by high passivation in nanocrystalline HfO2 matrix
Authors: Dascalescu Ioana , Palade Catalin , Slav Adrian , Stavarache Ionel , Cojocaru Ovidiu , Teodorescu Valentin Serban , Maraloiu Valentin-Adrian , Lepadatu Ana-Maria , Ciurea Magdalena Lidia , Stoica Toma 
Published: February 2024

AbstractSiGeSn nanocrystals (NCs) in oxides are of considerable interest for photo-effect applications due to the fine-tuning of the optical bandgap by quantum confinement in NCs. We present a detailed study regarding the silicon germanium tin (SiGeSn) NCs embedded in a nanocrystalline hafnium oxide (HfO2) matrix fabricated by using magnetron co-sputtering deposition at room temperature and rapid thermal annealing (RTA). The NCs were formed at temperatures in the range of 500–800 °C. RTA was performed to obtain SiGeSn NCs with surfaces passivated by the embedding HfO2 matrix. The formation of NCs and β-Sn segregation were discussed in relation to the deposition and processing conditions by employing HRTEM, XRD and Raman spectroscopy studies. The spectral photosensitivity exhibited up to 2000 nm in short-wavelength infrared (SWIR) depending on the Sn composition was obtained. Comparing to similar results on GeSn NCs in SiO2 matrix, the addition of Si offers a better thermal stability of SiGeSn NCs, while the use of HfO2 matrix results in better passivation of NCs increasing the SWIR photosensitivity at room temperature. These results suggest that SiGeSn NCs embedded in an HfO2 matrix are a promising material for SWIR optoelectronic devices.
The causal effects of genetically predicted alcohol consumption on endometrial cancer risk from a Mendelian randomization study
Authors: Yang Jie , Qu Xiang , Zheng An-jie , Jiang Fan , Chang Hui , zhang Jin-ru , Yan Li-juan , Ning Peng 
Published: February 2024

AbstractEndometrial cancer (EC) is a common gynecological tumor in females with an increasing incidence over the past few decades. Alcohol consumption has been linked to the occurrence of various cancers; However, epidemiological studies have shown inconsistent associations between alcohol consumption and EC risk. In order to avoid the influence of potential confounding factors and reverse causality in traditional epidemiological studies, we used a method based on genetic principles-Mendelian randomization (MR) analysis to test whether there is a causal relationship between alcohol consumption and EC. MR analysis was conducted using publicly available summary-level data from genome-wide association studies (GWAS). Fifty-seven single nucleotide polymorphisms (SNPs) were extracted as instrumental variables for alcohol exposure from the GWAS and Sequencing Consortium of Alcohol and Nicotine GWAS summary data involving 941,287 participants of European ancestry. SNPs for EC were obtained from the Endometrial Cancer Association Consortium, the Endometrial Cancer Epidemiology Consortium, and the UK Biobank, involving 121,885 European participants. The inverse variance weighted (IVW) method was used as the primary method to estimate the causal effect, and the MR-Egger regression and weighted median method were used as supplementary methods. Sensitivity analyses were conducted using the Mendelian Randomization Pleiotropy RESidual Sum and Outlier global test, MR-Egger intercept test, and leave-one-out analysis to evaluate the impact of pleiotropy on causal estimates. An increase of 1 standard deviation of genetically predicted log-transformed alcoholic drinks per day was associated with a 43% reduction in EC risk [odds ratio (OR) = 0.57, 95% confidence interval (CI) 0.41–0.79, P < 0.001]. Subgroup analysis of EC revealed that alcohol consumption was a protective factor for endometrioid endometrial cancer (EEC) (OR = 0.56, 95% CI 0.38–0.83, P = 0.004) but not for non-endometrioid endometrial cancer (NEC) (OR = 1.36, 95% CI 0.40–4.66, P = 0.626). The MR-Egger regression and weighted median method yielded consistent causal effects with the IVW method. The consistent results of sensitivity analyses indicated the reliability of our causal estimates. Additionally, alcohol consumption was associated with decreased human chorionic gonadotropin (HCG) and insulin-like growth factor 1 (IGF1) levels. This MR study suggests that genetically predicted alcohol consumption is a protective factor for EC, particularly for EEC, and this protective effect may be mediated through the reduction of HCG and IGF1.
Adaptation and validation of a quantitative vanA/vanB DNA screening assay on a high-throughput PCR system
Authors: Giersch Katja , Tanida Konstantin , Both Anna , Nörz Dominik , Heim Denise , Rohde Holger , Aepfelbacher Martin , Lütgehetmann Marc 
Published: February 2024

AbstractVancomycin resistant enterococci (VRE) are a leading cause of ICU-acquired bloodstream infections in Europe. The bacterial load in enteral colonization may be associated with a higher probability of transmission. Here, we aimed to establish a quantitative vanA/vanB DNA real-time PCR assay on a high-throughput system. Limits of detection (LOD), linear range and precision were determined using serial bacterial dilutions. LOD was 46.9 digital copies (dcp)/ml for vanA and 60.8 dcp/ml for vanB. The assay showed excellent linearity between 4.7 × 101 and 3.5 × 105 dcp/ml (vanA) and 6.7 × 102 and 6.7 × 105 dcp/ml (vanB). Sensitivity was 100% for vanA and vanB, with high positive predictive value (PPV) for vanA (100%), but lower PPV for vanB (34.6%) likely due to the presence of vanB DNA positive anerobic bacteria in rectal swabs. Using the assay on enriched VRE broth vanB PPV increased to 87.2%. Quantification revealed median 2.0 × 104 dcp/ml in PCR positive but VRE culture negative samples and median 9.1 × 104 dcp/ml in VRE culture positive patients (maximum: 107 dcp/ml). The automated vanA/B_UTC assay can be used for vanA/vanB detection and quantification in different diagnostic settings and may support future clinical studies assessing the impact of bacterial load on risk of infection and transmission.
Healthy eating index-2015 and its association with the prevalence of stroke among US adults
Authors: Wu Xiao-Fei , Yin Fei , Wang Gui-Jie , Lu Ye , Jin Rong-Fei , Jin Dong-Lin 
Published: February 2024

AbstractThis study aims to investigate the relationship between the healthy eating index (HEI) and the prevalence of stroke within a diverse United States population. Employing a cross-sectional design, we utilized data sourced from the National Health and Nutrition Examination Survey (NHANES). Dietary information was collected from participants and HEI scores were computed. NHANES employed stratified multistage probability sampling, with subsequent weighted analysis following NHANES analytical guidelines. Thorough comparisons were made regarding the baseline characteristics of individuals with and without stroke. Weighted multivariable logistic regression analysis and restricted cubic spline (RCS) methods were employed to ascertain the association between stroke risk and HEI, with LASSO regression utilized to identify dietary factors most closely linked to stroke risk. Additionally, we constructed a nomogram model incorporating key dietary factors and assessed its discriminatory capability using the receiver operating characteristic (ROC) curve. Our study encompassed 43,978 participants, representing an estimated 201 million U.S. residents. Participants with a history of stroke exhibited lower HEI scores than their non-stroke counterparts. Logistic regression analysis demonstrated a robust association between lower HEI scores and stroke, even after adjusting for confounding variables. RCS analysis indicated a nonlinear negative correlation between HEI and stroke risk. Furthermore, detailed subgroup analysis revealed a significant gender-based disparity in the impact of dietary quality on stroke risk, with females potentially benefiting more from dietary quality improvements. Sensitivity analysis using unweighted logistic regression yielded results consistent with our primary analysis. The nomogram model, based on key dietary factors identified through LASSO regression, demonstrated favorable discriminatory power, with an area under the curve (AUC) of 79.3% (95% CI 78.4–81.2%). Our findings suggest that higher HEI scores are inversely related to the risk of stroke, with potential greater benefits for women through dietary quality enhancement. These results underscore the importance of improving dietary quality for enhanced stroke prevention and treatment.
Strontium isotope proxy of sedimentological records reveals uplift and erosion in the Southeastern Neo-Tethys ocean during the late Cretaceous
Authors: Navidtalab Amin , Mehrabi Hamzeh , Shafaii Moghadam Hadi , Rahimpour-Bonab Hossain 
Published: February 2024

AbstractThe mutual interplays between plate tectonic processes, orogenesis and continental uplift, high-flux magmatism, and high sedimentation rates can affect the geochemical signatures and composition of marine sediments. Here, we examine two major disconformities, the Cenomanian–Turonian boundary (CT-ES) and the middle Turonian (mT-ES) exposure surfaces, from the Upper Cretaceous sedimentary successions of the southeastern Neo-Tethys Ocean in the Zagros Basin (Iran). The disconformities are expressed as distinct positive peaks in rubidium (Rb) contents and 87Sr/86Sr isotopic ratios of carbonates. The 87Sr/86Sr values of samples bracketing the disconformities in seven well cores give average age ranges of 94.4–93.6 Ma for the CT-ES and 91–86 Ma for the mT-ES. These ages fall in the timespan of forearc/ophiolite formation through subduction initiation in the Neo-Tethys realm (southern margin of Eurasia), high convergence velocities between Arabia and Eurasia, and blueschist exhumation. All these processes involved buckling of the Neo-Tethyan lithosphere, initiating the Neo-Tethys closure and a high erosion rate on the Eurasian margin. The first two mechanisms exerted considerable compressional forces on the adjacent carbonate platforms, reactivated basement faults, and led to the uplift and erosion of the Arabian Plate, which provided the high contents of Rb and the high 87Sr/86Sr ratios in the carbonates.
Prevalence and correlates of internalizing and externalizing mental health problems among in-school adolescents in eastern Ethiopia: a cross-sectional study
Authors: Hunduma Gari , Dessie Yadeta , Geda Biftu , Yadeta Tesfaye Assebe , Deyessa Negussie 
Published: February 2024

AbstractAdolescent’s mental health issues are a major social burden and a significant public health issue, but they have not received enough attention in Ethiopia. Therefore, this study aimed to determine the prevalence and correlates of internalizing and externalizing mental health problems among in-school adolescents in the Harari region, eastern Ethiopia. A cross-sectional study was conducted among 3227 in-school adolescents. Multistage sampling was used to select schools and eligible students to participate in the study. A guided, self-administered strength and difficulty questionnaire measured mental health problems. Data were double-entered, validated, and cleaned using EpiData 3.1 and analyzed using STATA version 17. Ordinal logistic regression analysis was performed to estimate the adjusted odds ratio between mental health problems and their correlates. Statistical significance was set at p-value < 0.05. The magnitudes of mental health problems among in-school adolescents by subscale was 24.17% (95% CI 22.72; 25.67) for internalizing and 11.93% (95% CI 10.85; 13.09) for externalizing problems. A high internalizing problem score was associated with females, rural residents, alcohol users, attending public schools, those bullied at school, and those in the lowest wealth index. Likewise, the likelihood of a high externalizing problem score was high among alcohol users, adolescents whose fathers are uneducated, rural, and bullied at school. The study suggests that mental health problems are prevalent among in-school adolescents in Ethiopia, especially internalizing problems. The study also identifies several risk factors associated with internalizing and externalizing problems, such as wealth index, school types, alcohol use, bullying, and rural residence. These factors may indicate the need for more mental health awareness and support programs for adolescents in Ethiopia. This highlights that schools and communities should prioritize mental health awareness and support programs for adolescents. These programs should be tailored to address the specific needs of the population, such as rural residents, those in the lowest wealth index, and those who have experienced bullying.
Association of perinatal factors with neurodevelopmental referrals in a population-based cohort study in Japan
Authors: Kyono Yuki , Nishiyama Masahiro , Kawamura Aoi , Oikawa Shizuka , Tokumoto Shoichi , Yamaguchi Hiroshi , Tomioka Kazumi , Nozu Kandai , Mishina Hiroki , Nagase Hiroaki 
Published: February 2024

AbstractAlthough the causes of neurodevelopmental disorders remain unknown, several environmental risk factors have attracted considerable attention. We conducted a retrospective, longitudinal, population-based cohort study using data from infant health examinations of children born to mothers with pregnancies between April 1, 2014 and March 31, 2016 in Kobe City to identify the perinatal factors associated with neurodevelopmental referrals in 3-year-old children. There were 15,223 and 1283 children in the normal and referral groups, respectively. Neurodevelopmental referrals at the health checkup for 3-year-old children were significantly associated with the lack of social support during pregnancy (adjusted odds ratio [aOR] 1.99, 99% CI 1.14–3.45, p = 0.001), history of psychiatric consultation (aOR 1.56, 99% CI 1.10–2.22, p = 0.001), no social assistance post-delivery (aOR 1.49, 99% CI 1.03–2.16, p = 0.006), Edinburgh Post-natal Depression Scale (EPDS) score ≥ 9 (aOR 1.36, 99% CI 1.01–1.84, p = 0.008), infant gender (male) (aOR 2.51, 99% CI 2.05–3.06, p < 0.001), and cesarean delivery (aOR 1.39, 99% CI 1.11–1.75, p < 0.001). In conclusion, this exploratory study in the general Japanese population identified six perinatal factors associated with neurodevelopmental referrals in 3-year-old children: infant gender (male), cesarean section, maternal history of psychiatric consultation, EPDS score ≥ 9, lack of social support during pregnancy, and no social assistance post-delivery.
Pan-cancer analysis reveals potential immunological and prognostic roles of METTL7A in human cancers
Authors: Wang Bin , Jiang Jingjing , Luo Danju , Wang Xiong 
Published: February 2024

AbstractMethyltransferase-like protein 7A (METTL7A) is an m6A RNA methyltransferase that has been linked to cancer prognosis and drug resistance. However, a comprehensive analysis of METTL7A is lacking. The expression of METTL7A, prognostic performance, correlation with microsatellite instability (MSI), tumor mutational burden (TMB), and immune infiltration was investigated in The Cancer Genome Atlas (TCGA). Immunohistochemistry staining was applied to detect METTL7A in 6 tumors. METTL7A was significantly decreased in 19 cancers in TCGA including LUAD. Alterations of METTL7A include amplification and mutation, and epigenetic alterations revealed increased promoter methylation may result in down-regulation of METTL7A in LUAD. We also found that METTL7A was linked to both TMB and MSI in LUAD. METTL7A was increasingly correlated with invasive immune cells, while being negatively associated with Macrophages M0, Mast cells activated, activated memory CD4 T cells, CD8 T cells, and follicular helper T cells in several tumors. Additionally, METTL7A showed similar correlation with immune therapy-related genes across cancers. Our biological validation found that the protein levels of METTL7A were down-regulated in breast cancer (BRCA), endometrioid cancer (UCEC), colon cancer (COAD), prostate cancer (PRAD), and kidney clear cell carcinoma (KIRC), as detected by immunohistochemistry staining. Overall, our work indicates that METTL7A may serve as promising diagnostic and prognostic indicator of LUAD, and our work sheds light on the potential immunological and prognostic roles of METTL7A in human cancers.
Novel nomograms based on microvascular invasion grade for early-stage hepatocellular carcinoma after curative hepatectomy
Authors: Chen Hengkai , Ye Honghao , Ye Linfang , Lin Fangzhou , Shi Yingjun , Zhong Aoxue , Guan Guoxian , Zhuang Jinfu 
Published: February 2024

AbstractMicrovascular invasion (MVI) is a critical risk factor for postoperative recurrence of hepatocellular carcinoma (HCC). This study aimed to firstly develop and validate nomograms based on MVI grade for predicting recurrence, especially early recurrence, and overall survival in patients with early-stage HCC after curative resection. We retrospectively reviewed the data of patients with early-stage HCC who underwent curative hepatectomy in the First Affiliated Hospital of Fujian Medical University (FHFU) and Mengchao Hepatobiliary Hospital of Fujian Medical University (MHH). Kaplan–Meier curves and Cox proportional hazards regression models were used to analyse disease-free survival (DFS) and overall survival (OS). Nomogram models were constructed on the datasets from the 70% samples of and FHFU, which were validated using bootstrap resampling with 30% samples as internal validation and data of patients from MHH as external validation. A total of 703 patients with early-stage HCC were included to create a nomogram for predicting recurrence or metastasis (DFS nomogram) and a nomogram for predicting survival (OS nomogram). The concordance indexes and calibration curves in the training and validation cohorts showed optimal agreement between the predicted and observed DFS and OS rates. The predictive accuracy was significantly better than that of the classic HCC staging systems.
Boosting the high rate and durability of lithium–sulfur batteries using a bidirectional catalyst of a polyoxometalate-cyclodextrin supramolecular compound
Authors: Song Jian , Jiang Yuanyuan , Lu Yizhong , Cao Yundong , Zhang Yuxi , Fan Linlin , Liu Hong , Gao Guanggang 
Published: February 2024

PW12 and CD in PW12-CD supramolecular compound synergetically anchor polysulfides. PW12 bidirectionally catalyzes polysulfides conversion, accompanied by reversible transformation between reduction and oxidation states.