bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Role of Extrinsic Motivation in Securing Actors’ Compliance with the International Anti-Money Laundering/Counterterrorist Financing Regime
Authors: Alshamsi Reem 
Published: October 2023

Abstract
The effectiveness of the Financial Action Task Force (FATF) international regime to govern anti-money laundering (AML) and counterterrorist financing (CTF) has been questioned since its establishment. In theory, the FATF’s network of multilevel actors should protect the integrity of the international financial system. The empirical evidence in this article shows that the FATF has made a difference in ensuring states’ (official) compliance with its measures, using extrinsic motivation tools; for example, ranking noncompliant states. However, it argues that such motivation only ensures actors’ minimum compliance, meaning that the regime’s effectiveness is suboptimal, while fostering intrinsic motivation would improve actors’ performance. Therefore, it is essential to understand why actors comply with the FATF approach and how they could be persuaded to achieve better compliance so that the regime’s effectiveness is feasible. This article explores these questions, using interviews with thirty practitioners in three locations, supported by a qualitative analysis of documentary data.
“He Wreaks Havoc on Earth”
Authors: Salati Marco 
Published: October 2023

Abstract
This article draws attention to a criminal case recorded at the High Court of Ottoman Aleppo in 1655. Although extremely concise, the document is a good example not only of daily legal practice in an Ottoman court but also of the interaction between the judicial system and the urban elite in cases involving matters of public order that were perceived as particularly sensitive. The list of persons called before the court for an official statement of accusation is a sort of who’s who of Aleppine society. It includes some major Ottoman officeholders of the mid-17th century who were resident in Aleppo and other local notables.
A Mexican Renascence
Authors: Kane Louise 
Published: October 2023

Abstract
This article explores the periodical contributions of the Mexican-Jewish writer and editor Anita Brenner (1905–1974). It argues that Brenner’s periodical contributions—primarily relating to art criticism and published in diverse outlets such as The Nation, Mexican Folkways, the Brooklyn Daily Eagle, and Mademoiselle—decenter ideas of Mexico as a site of peripheral avant-gardism and reveal how Brenner was a pioneer of a transnational and, in some ways, distinctly female avant-garde network.
Tarsila do Amaral
Authors: Mariella Rosita 
Published: October 2023

Abstract
In the field of visual arts, painter Tarsila do Amaral was a pioneer in her revindication of ‘peripheral’ areas, as well as in her opposition to an exclusive Eurocentric vision of the world. The article highlights how her contribution was crucial to an early approach to decolonization that used the notion of antropofagia to present the colonized in an act of ‘devouring’ the colonizer, assimilating certain aspects and discarding others to process and build new, independent identities. Considering her white, upper-class and cosmopolitan background, the article also explores the limits of her colonial-related art practices and the common trap of exoticism in the arts. Using the history of Tarsila do Amaral as a case study, this study will question how artists from ‘peripheral’ areas were making use of their access to native cultures in order to be part of the established European art scene and hegemonic discourse.
SOD1 is a novel prognostic biomarker of acute kidney injury following cardiothoracic surgery
Authors: Holthoff Joseph H. , Harville Yanping , Herzog Christian , Juncos Luis A. , Karakala Nithin , Arthur John M. 
Published: October 2023

Abstract
Background
Acute kidney injury (AKI) is a major burden among hospitalized and critical care patients. Among hospitalized patients that progress to severe AKI there is increased risk for morbidity, mortality, and the need for renal replacement therapy (RRT). As there are no specific treatments for AKI, the discovery of novel biomarkers that predict the progression of AKI may aid in timely implementation of supportive care to improve outcomes.

Methods
We collected urine from 204 patients that developed Stage 1 AKI by AKIN criteria within 72 h following cardiothoracic surgery. Urine samples were collected at the time of the initial diagnosis of AKI and stored at −80° C. Among the 204 patients, 25 progressed to a composite primary outcome of Stage 3 AKI, requirement of RRT, or 30-day mortality. The remaining 179 patients did not progress beyond Stage 2 AKI and were considered controls. Urinary concentrations of SOD1 and SOD1 activity were measured following collection of all samples. Samples were thawed and urinary superoxide dismutase 1 (SOD1) concentrations were measured by sandwich ELISA and urinary SOD1 activity was measured through a commercially available colorimetric assay.

Results
Urinary concentrations of SOD1 were significantly elevated (67.0 ± 10.1 VS 880.3 ± 228.8 ng/ml, p < 0.0001) in patients that progressed to severe AKI and were able to predict the progression to severe AKI (AUC – 0.85, p < 0.0001). Furthermore, total SOD activity also increased in the urine of patients that required RRT (77.6% VS 49.81% median inhibition, p < 0.01) and was able to predict the need for RRT (AUC: 0.83, p < 0.01).

Conclusion
These findings show that urinary SOD1 concentrations and SOD activity are novel prognostic biomarkers for severe AKI following cardiothoracic surgery.
Implant breakage after shoulder arthroplasty: a systematic review of data from worldwide arthroplasty registries and clinical trials
Authors: Liebhauser Martin , Hohenberger Gloria , Lohberger Birgit , Hauer Georg , Deluca Amelie , Sadoghi Patrick 
Published: October 2023

Abstract
Background
Implant breakage after shoulder arthroplasty is a rare complication after aseptic loosening, infection or persistent pain, resulting in malfunction of the components requiring revision surgery. This correlates with a high burden for the patient and increasing costs. Specific data of complication rates and implant breakage are available in detailed arthroplasty registries, but due to the rare occurrence and possibly underestimated value rarely described in published studies. The aim of this systematic review was to point out the frequency of implant breakage after shoulder arthroplasty. We hypothesized that worldwide arthroplasty registry datasets record higher rates of implant breakage than clinical trials.

Methods
PubMed, MEDLINE, EMBASE, CINHAL, and the Cochrane Central Register of Controlled Trials database were utilized for this systematic review using the items “(implant fracture/complication/breakage) OR (glenoid/baseplate complication/breakage) AND (shoulder arthroplasty)” according to the PRISMA guidelines on July 3rd, 2023. Study selection, quality assessment, and data extraction were conducted according to the Cochrane standards. Case reports and experimental studies were excluded to reduce bias. The breakage rate per 100,000 observed component years was used to compare data from national arthroplasty registries and clinical trials, published in peer-reviewed journals. Relevant types of shoulder prosthetics were analyzed and differences in implant breakage were considered.

Results
Data of 5 registries and 15 studies were included. Rates of implant breakage after shoulder arthroplasty were reported with 0.06–0.86% in registries versus 0.01–6.65% in clinical studies. The breakage rate per 100,000 observed component years was 10 in clinical studies and 9 in registries. There was a revision rate of 0.09% for registry data and 0.1% for clinical studies within a 10-year period. The most frequently affected component in connection with implant fracture was the glenoid insert.

Conclusion
Clinical studies revealed a similar incidence of implant failure compared to data of worldwide arthroplasty registries. These complications arise mainly due to breakage of screws and glenospheres and there seems to be a direct correlation to loosening. Periprosthetic joint infection might be associated with loosening of the prosthesis and subsequent material breakage. We believe that this analysis can help physicians to advise patients on potential risks after shoulder arthroplasty.

Level of evidence
III.
A magnetic solid phase chemiluminescent immunoassay for quantification of Cystatin C in human serum
Authors: He Jian , Liang Ping , Wang Tingting , Han Shuang 
Published: October 2023

AbstractA chemiluminescent immunoassay for human serum Cystatin C (Cys C) was established using a direct-antibody sandwich model. The immunoassay kit uses magnetic separation technology, using magnetic particles as the reaction solid phase, alkaline phosphatase as the marker enzyme, and a new chemiluminescent substrate APLS as the substrate. It has the characteristics of high sensitivity and short reaction time. This product uses high-affinity antibodies, resulting in a high specificity. The established method showed good accuracy, uniformity, and stability. The limit of detection was 2.39 ng/mL. The intra-assay coefficient of variation (CV) was 3.36%–6.00%, the interassay CV was 4.12%–5.35%, and the recovery rate was 99.07%. The correlation coefficient (r) of Cys-C kit was 0.999388 ≥ 0.9900. The accuracy of the developed method was tested by automatic chemiluminescence instrument (P > 0.05). The lowest titer was 0.92500, and the highest was 1.10000. The developed method showed a good correlation with the product from Roche by comparing these two kits in 240 clinical samples from China. In total, 1392 clinical patient from China samples were measured using the reagent kit developed in this study.
Antecedents predicting digital contact tracing acceptance: a systematic review and meta-analysis
Authors: Kuo Kuang-Ming 
Published: October 2023

AbstractAn awareness of antecedents of acceptance of digital contact tracing (DCT) can enable healthcare authorities to design appropriate strategies for fighting COVID-19 or other infectious diseases that may emerge in the future. However, mixed results about these antecedents are frequently reported. Most prior DCT acceptance review studies lack statistical synthesis of their results. This study aims to undertake a systematic review and meta-analysis of antecedents of DCT acceptance and investigate potential moderators of these antecedents. By searching multiple databases and filtering studies by using both inclusion and exclusion criteria, 76 and 25 studies were included for systematic review and meta-analysis, respectively. Random-effects models were chosen to estimate meta-analysis results since Q, I2, and H index signified some degree of heterogeneity. Fail-safe N was used to assess publication bias. Most DCT acceptance studies have focused on DCT related factors. Included antecedents are all significant predictors of DCT acceptance except for privacy concerns and fear of COVID-19. Subgroup analysis showed that individualism/collectivism moderate the relationships between norms/privacy concerns and intention to use DCT. Based on the results, the mean effect size of antecedents of DCT acceptance and the potential moderators may be more clearly identified. Appropriate strategies for boosting the DCT acceptance rate can be proposed accordingly.
The burden of mitochondrial disease with associated seizures: systematic literature reviews of health-related quality of life, utilities, costs and healthcare resource use data
Authors: Bertini Enrico , Gregg Emily , Bartlett Chris , Senthilnathan Vij , Arber Mick , Watkins Deborah , Graziadio Sara , Tomazos Ioannis 
Published: October 2023

Abstract
Background
Mitochondrial disease is a degenerative, progressive, heterogeneous group of genetic disorders affecting children and adults. Mitochondrial disease is associated with morbidity and mortality, with predominantly neurological and neuromuscular symptoms including dystonia, weakness, encephalopathy, developmental delay and seizures. Seizures are one of the most common and severe manifestations of mitochondrial disease. These seizures are typically refractory to common anti-seizure therapies. There are no approved disease-modifying treatments for mitochondrial disease. Our objective was to conduct two systematic literature reviews to identify health-related quality of life (HRQoL), utilities, costs and healthcare resource use data in mitochondrial disease with associated seizures.

Methods
A range of databases and information sources were searched up to July 2022 to identify eligible studies. Search strategies included a range of variant terms for mitochondrial disease and HRQoL, utilities, cost and healthcare resource use outcomes. Two reviewers independently assessed articles against the eligibility criteria; studies were extracted by one reviewer and checked by a second. Risk of bias was assessed for studies reporting HRQoL data. Results were narratively assessed.

Results
Seven studies were eligible for the HRQoL and utilities review. The studies used different tools to report data, and despite the variability in methods, HRQoL scores across the studies showed moderate/severe disease in patients with mitochondrial disease with associated seizures. Parents of patients with mitochondrial disease with associated seizures were characterised by high total parenting stress. No studies reported utilities data. Two case reports and one retrospective review of medical records of children who died in hospital were eligible for the costs and resource use review. These provided limited information on the duration of hospital stay, in an intensive care unit (ICU), on mechanical ventilation. No studies reported costs data.

Conclusion
These reviews highlight the limited HRQoL, utilities, costs and resource use data and the variability of instruments used in mitochondrial disease with associated seizures. However, the data available indicate that mitochondrial disease with associated seizures affects patients’ and caregivers’ HRQoL alike. No robust conclusion can be drawn on the impact of mitochondrial disease with associated seizures on hospital or ICU length of stay.
Trial registration PROSPERO: CRD42022345005.
Is a preoperative multidisciplinary team meeting (cost)effective to improve outcome for high-risk adult patients undergoing noncardiac surgery: the PREPARATION study—a multicenter stepped-wedge cluster randomized trial
Authors: Vernooij Jacqueline E. M. , Boerlage Romijn M. , Doggen Carine J. M. , Preckel Benedikt , Dirksen Carmen D. , van Leeuwen Barbara L. , Spruit Rutger J. , Festen Suzanne , van der Wal-Huisman Hanneke , van Basten Jean P. , Kalkman Cor J. , Koning Nick J. ,   PREPARATION study investigators, van der Sloot Koene , Dias Esther M. , Kal Jasper E. , van den Nieuwenhuyzen Marjolein C. O. , di Biase Manuela , Hagenaars Martin , Oedairadjsingh Bies , van den Ende Taco , Timmerman Michel , Segers Zjuul , Schoester Dominique H. P. A. M. , Vons Kristy M. J. , Filius A. , van Harten Wim , Poolman Rudolf W. , Reijnen Michel M. P. J. , Noordzij Peter G. , van Munster Barbara C. 
Published: October 2023

Abstract
Background
As a result of increased life expectancy and improved care for patients suffering from chronic disease, the number of patients with multimorbidity requiring surgical intervention is increasing. For complex surgical patients, it is essential to balance the potential benefits of surgical treatment against the risk of permanent loss of functional capacity and quality of life due to complications. European and US guidelines on perioperative care recommend preoperative multidisciplinary team (MDT) discussions for high-risk noncardiac surgical patients. However, the evidence underlying benefits from preoperative MDT meetings with all relevant perioperative specialties present is limited. The current study aims to investigate the effect of implementation of preoperative MDT discussions for high-risk patients undergoing noncardiac surgery on serious adverse events.

Methods/design
PREPARATION is a stepped-wedge cluster randomized trial in 14 Dutch hospitals without currently established preoperative MDT meeting. The intervention, preoperative MDT meetings, will be implemented sequentially with seven blocks of 2 hospitals switching from control (preoperative screening as usual) to the intervention every 3 months. Each hospital will be randomized to one of seven blocks. We aim to include 1200 patients. The primary outcome is the incidence of serious adverse events at 6 months. Secondary outcomes include (cost)effectiveness, functional outcome, and quality of life for up to 12 months.

Discussion
PREPARATION is the first study to assess the effectiveness of a preoperative MDT meeting for high-risk noncardiac surgical patients in the presence of an anesthesiologist. If the results suggest that preoperative MDT discussions for high-risk patients are (cost)-effective, the current study facilitates implementation of preoperative MDT meetings in clinical practice.

Trial registration
ClinicalTrials.gov NCT05703230. Registered on 11/09/2022.
Chemoautotrophic production of gaseous hydrocarbons, bioplastics and osmolytes by a novel Halomonas species
Authors: Faulkner Matthew , Hoeven Robin , Kelly Paul P. , Sun Yaqi , Park Helen , Liu Lu-Ning , Toogood Helen S. , Scrutton Nigel S. 
Published: October 2023

Abstract
Background
Production of relatively low value, bulk commodity chemicals and fuels by microbial species requires a step-change in approach to decrease the capital and operational costs associated with scaled fermentation. The utilisation of the robust and halophilic industrial host organisms of the genus Halomonas could dramatically decrease biomanufacturing costs owing to their ability to grow in seawater, using waste biogenic feedstocks, under non-sterile conditions.

Results
We describe the isolation of Halomonas rowanensis, a novel facultative chemoautotrophic species of Halomonas from a natural brine spring. We investigated the ability of this species to produce ectoine, a compound of considerable industrial interest, under heterotrophic conditions. Fixation of radiolabelled NaH14CO3 by H. rowanensis was confirmed in mineral medium supplied with thiosulfate as an energy source. Genome sequencing suggested carbon fixation proceeds via a reductive tricarboxylic acid cycle, and not the Calvin–Bensen–Bassham cycle. The mechanism of energy generation to support chemoautotrophy is unknown owing to the absence of an annotated SOX-based thiosulfate-mediated energy conversion system. We investigated further the biotechnological potential of the isolated H. rowanensis by demonstrating production of the gaseous hydrocarbon (bio-propane), bioplastics (poly-3-hydroxybutyrate) and osmolytes (ectoine) under heterotrophic and autotrophic CO2 fixation growth conditions.

Conclusions
This proof-of-concept study illustrates the value of recruiting environmental isolates as industrial hosts for chemicals biomanufacturing, where CO2 utilisation could replace, or augment, the use of biogenic feedstocks in non-sterile, industrialised bioreactors.
Upadacitinib effectiveness and factors associated with minimal disease activity achievement in patients with psoriatic arthritis: preliminary data of a real-life multicenter study
Authors: Luchetti Gentiloni Michele Maria , Paci Valentino , Carletto Antonio , Zabotti Alen , Ramonda Roberta , Chimenti Maria Sole , Dagna Lorenzo , Luciano Nicoletta , Piccinelli Anna , Giovannini Ivan , Striani Giovanni , Boffini Nicola , Sandri Gilda , Possemato Niccolò , Pantano Ilenia , Benfaremo Devis , Salvarani Carlo , Ciccia Francesco , Selmi Carlo , Moroncini Gianluca 
Published: October 2023

Abstract
Background
Upadacitinib (UPA) is a selective JAK inhibitor recently approved for the treatment of psoriatic arthritis (PsA). In this post-approval study, we aimed to evaluate the effectiveness and safety of UPA over 24 weeks and identify clinical predictors of response, in a multicentric cohort of patients affected by PsA.

Methods
One hundred and twenty-six patients with PsA treated with UPA were enrolled in 10 Italian centres. UPA effectiveness outcomes, such as the proportion of patients with MDA status, DAPSA remission, and low disease activity, ASDAS-CRP inactive and low disease activity, and change from baseline in DAPSA and ASDAS-CRP scores, were evaluated every 12 weeks until week 24. The proportion of DAPSA minor, moderate, and major improvement, and ASDAS clinically important improvement (CII) and major improvement (MI) were considered as well. All treatment-related adverse events were collected during the observation period. Clinical predictors of MDA response at week 24 were evaluated through multivariate analysis.

Results
At baseline, 124/126 (98%) and 54/126 (43%) patients showed peripheral and axial involvement, respectively; 110 (87%) patients were intolerant or resistant to biologic DMARDs.
At 24 weeks, MDA status, DAPSA remission, and ASDAS-CRP inactive disease were achieved in 47%, 23%, and 48% of patients, respectively. Minor, moderate, and major DAPSA improvement was observed in 67%, 39%, and 23%, respectively; while 65% and 35% achieved ASDAS-CRP CII and MI, respectively. The mean change from baseline was 15.9 ± 13.5 (p < 0.001) for DAPSA and 1.21 ± 0.97 (p < 0.001) for ASDAS-CRP. Thirteen patients (10%) discontinued UPA due to a lack of efficacy or non-serious adverse events. No serious adverse events were observed. Male gender (OR 2.54, 95% CI 1.03–6.25 p = 0.043), being naïve to biological DMARDs (OR 4.13, 95% CI 1.34–12.71, p = 0.013) and elevated baseline CRP (OR 2.49, 95% CI 1.02–6.12, p = 0.046) were associated with MDA response at week 24.

Conclusions
This is one of the first real-life studies supporting the effectiveness of UPA and its safety profile in PsA patients. Furthermore, the study identifies predictors of MDA response to UPA treatment at 6 months.
Speech emotion recognition based on Graph-LSTM neural network
Authors: Li Yan , Wang Yapeng , Yang Xu , Im Sio-Kei 
Published: October 2023

AbstractCurrently, Graph Neural Networks have been extended to the field of speech signal processing. It is the more compact and flexible way to represent speech sequences by graphs. However, the structures of the relationships in recent studies are tend to be relatively uncomplicated. Moreover, the graph convolution module exhibits limitations that impede its adaptability to intricate application scenarios. In this study, we establish the speech-graph using feature similarity and introduce a novel architecture for graph neural network that leverages an LSTM aggregator and weighted pooling. The unweighted accuracy of 65.39% and the weighted accuracy of 71.83% are obtained on the IEMOCAP dataset, achieving the performance comparable to or better than existing graph baselines. This method can improve the interpretability of the model to some extent, and identify speech emotion features effectively.