bluuebunny/crossref_metadata_2025_split huggingface dataset:
Lattice Engineering on Li2CO3‐Based Sacrificial Cathode Prelithiation Agent for Improving the Energy Density of Li‐Ion Battery Full‐Cell
Authors: Zhu Yuanlong , Chen Yilong , Chen Jianken , Yin Jianhua , Sun Zhefei , Zeng Guifan , Wu Xiaohong , Chen Leiyu , Yu Xiaoyu , Luo Haiyan , Yan Yawen , Zhang Haitang , Zhang Baodan , Kuai Xiaoxiao , Tang Yonglin , Xu Juping , Yin Wen , Qiu Yongfu , Zhang Qiaobao , Qiao Yu , Sun Shi‐Gang 
Published: December 2023

AbstractDeveloping sacrificial cathode prelithiation technology to compensate for active lithium loss is vital for improving the energy density of lithium‐ion battery full‐cells. Li2CO3 owns high theoretical specific capacity, superior air stability, but poor conductivity as an insulator, acting as a promising but challenging prelithiation agent candidate. Herein, extracting a trace amount of Co from LiCoO2 (LCO), a lattice engineering is developed through substituting Li sites with Co and inducing Li defects to obtain a composite structure consisting of (Li0.906Co0.043▫0.051)2CO2.934 and ball milled LiCoO2 (Co‐Li2CO3@LCO). Notably, both the bandgap and Li─O bond strength have essentially declined in this structure. Benefiting from the synergistic effect of Li defects and bulk phase catalytic regulation of Co, the potential of Li2CO3 deep decomposition significantly decreases from typical >4.7 to ≈4.25 V versus Li/Li+, presenting >600 mAh g−1 compensation capacity. Impressively, coupling 5 wt% Co‐Li2CO3@LCO within NCM‐811 cathode, 235 Wh kg−1 pouch‐type full‐cell is achieved, performing 88% capacity retention after 1000 cycles.
Direct Synthesis of Polyimide Curly Nanofibrous Aerogels for High‐Performance Thermal Insulation Under Extreme Temperature
Authors: Wang Sai , Ding Ruida , Liang Guoqiang , Zhang Wei , Yang Fengjin , Tian Yucheng , Yu Jianyong , Zhang Shichao , Ding Bin 
Published: December 2023

AbstractMaintaining human body temperature is one of the basic needs for living, which requires high‐performance thermal insulation materials to prevent heat exchange with external environment. However, the most widely used fibrous thermal insulation materials always suffer from the heavy weight, weak mechanical property, and moderate capacity to suppress heat transfer, resulting in limited personal cold and thermal protection performance. Here, an ultralight, mechanically robust, and thermally insulating polyimide (PI) aerogel is directly synthesized via constructing 3D interlocked curly nanofibrous networks during electrospinning. Controlling the solution/water molecule interaction enables the rapid phase inversion of charged jets, while the multiple jets are ejected by regulating charge density of the fluids, thus synergistically allowing numerous curly nanofibers to interlock and cross‐link with each other to form porous aerogel structure. The resulted PI aerogel integrates the ultralight property with density of 2.4 mg cm−3, extreme temperature tolerance (mechanical robustness over −196 to 300 °C), and thermal insulation performance with ultralow thermal conductivity of 22.4 mW m−1 K−1, providing an ideal candidate to keep human thermal comfort under extreme temperature. This work can provide a source of inspiration for the design and development of nanofibrous aerogels for various applications.
Meta‐Analysis of Integrated Proteomic and Transcriptomic Data Discerns Structure–Activity Relationship of Carbon Materials with Different Morphologies
Authors: Dumit Verónica I. , Liu Yuk‐Chien , Bahl Aileen , Kohonen Pekka , Grafström Roland C. , Nymark Penny , Müller‐Graf Christine , Haase Andrea , Pink Mario 
Published: December 2023

AbstractThe Fiber Pathogenicity Paradigm (FPP) establishes connections between fiber structure, durability, and disease‐causing potential observed in materials like asbestos and synthetic fibers. While emerging nanofibers are anticipated to exhibit pathogenic traits according to the FPP, their nanoscale diameter limits rigidity, leading to tangling and loss of fiber characteristics. The absence of validated rigidity measurement methods complicates nanofiber toxicity assessment. By comprehensively analyzing 89 transcriptomics and 37 proteomics studies, this study aims to enhance carbon material toxicity understanding and proposes an alternative strategy to assess morphology‐driven toxicity. Carbon materials are categorized as non‐fibrous, high aspect ratio with shorter lengths, tangled, and rigid fibers. Mitsui‐7 serves as a benchmark for pathogenic fibers. The meta‐analysis reveals distinct cellular changes for each category, effectively distinguishing rigid fibers from other carbon materials. Subsequently, a robust random forest model is developed to predict morphology, unveiling the pathogenicity of previously deemed non‐pathogenic NM‐400 due to its secondary structures. This study fills a crucial gap in nanosafety by linking toxicological effects to material morphology, in particular regarding fibers. It demonstrates the significant impact of morphology on toxicological behavior and the necessity of integrating morphological considerations into regulatory frameworks.
Fluidization and Application of Carbon Nano Agglomerations
Authors: Chen Sibo , Jiang Yaxin , Zhu Zhenxing , Zhang Qi , Zhang Chenxi , Zhang Qiang , Qian Weizhong , Zhang Shijun , Wei Fei 
Published: December 2023

AbstractCarbon nanomaterials are unique with excellent functionality and diverse structures. However, agglomerated structures are commonly formed because of small‐size effects and surface effects. Their hierarchical assembly into micro particles enables carbon nanomaterials to break the boundaries of classical Geldart particle classification before stable fluidization under gas‐solid interactions. Currently, there are few systematic reports regarding the structural evolution and fluidization mechanism of carbon nano agglomerations. Based on existing research on carbon nanomaterials, this article reviews the fluidized structure control and fluidization principles of prototypical carbon nanotubes (CNTs) as well as their nanocomposites. The controlled agglomerate fluidization technology leads to the successful mass production of agglomerated and aligned CNTs. In addition, the self‐similar agglomeration of individual ultralong CNTs and nanocomposites with silicon as model systems further exemplify the important role of surface structure and particle‐fluid interactions. These emerging nano agglomerations have endowed classical fluidization technology with more innovations in advanced applications like energy storage, biomedical, and electronics. This review aims to provide insights into the connections between fluidization and carbon nanomaterials by highlighting their hierarchical structural evolution and the principle of agglomerated fluidization, expecting to showcase the vitality and connotation of fluidization science and technology in the new era.
Pathway‐Dependent Self‐Assembly for Control over Helical Nanostructures and Topochemical Photopolymerization
Authors: Du Sifan , Jiang Yuqian , Jiang Hejin , Zhang Li , Liu Minghua 
Published: December 2023

AbstractPathway‐dependent self‐assembly, in which a single building block forms two or more types of self‐assembled nanostructures, is an important topic due to its mimic to the complexity in biology and manipulation of diverse supramolecular materials. Here, we report a pathway‐dependent self‐assembly using chiral glutamide derivatives (L or D‐PAG), which form chiral nanotwist and nanotube through a cooperative slow cooling and an isodesmic fast cooling process, respectively. Furthermore, pathway‐dependent self‐assembly can be harnessed to control over the supramolecular co‐assembly of PAG with a luminophore β‐DCS or a photopolymerizable PCDA. Fast cooling leads to the co‐assembled PAG/β‐DCS nanotube exhibiting green circularly polarized luminescence (CPL), while slow cooling to nanofiber with blue CPL. Additionally, fast cooling process promotes the photopolymerization of PCDA into a red chiral polymer, whereas slow cooling inhibits the polymerization. This work not only demonstrates the pathway‐dependent control over structural characteristics but also highlights the diverse functions emerged from the different assemblies.
The Diterpenoid Substrate Analogue 19‐nor‐GGPP Reveals Pronounced Methyl Group Effects in Diterpene Cyclisations
Authors: Taizoumbe Kizerbo A. , Goldfuss Bernd , Dickschat Jeroen S. 
Published: December 2023

AbstractThe substrate analogue 19‐nor‐geranylgeranyl diphosphate (19‐nor‐GGPP) was synthesised and incubated with 20 diterpene synthases, resulting in the formation of diterpenoids in all cases. A total of 23 different compounds were isolated from these enzyme reactions and structurally characterised, if possible including the experimental determination of absolute configurations through a stereoselective deuteration approach. In several cases the missing 19‐Me group in the substrate analogue resulted in opening of completely new reaction paths towards compounds with novel skeletons. DFT calculations were applied to gain a deeper understanding of these observed methyl group effects in diterpene biosynthesis.
Computer vision for plant pathology: A review with examples from cocoa agriculture
Authors: Sykes Jamie R. , Denby Katherine J. , Franks Daniel W. 
Published: December 2023

AbstractPlant pathogens can decimate crops and render the local cultivation of a species unprofitable. In extreme cases this has caused famine and economic collapse. Timing is vital in treating crop diseases, and the use of computer vision for precise disease detection and timing of pesticide application is gaining popularity. Computer vision can reduce labour costs, prevent misdiagnosis of disease, and prevent misapplication of pesticides. Pesticide misapplication is both financially costly and can exacerbate pesticide resistance and pollution. Here, we review the application and development of computer vision and machine learning methods for the detection of plant disease. This review goes beyond the scope of previous works to discuss important technical concepts and considerations when applying computer vision to plant pathology. We present new case studies on adapting standard computer vision methods and review techniques for acquiring training data, the use of diagnostic tools from biology, and the inspection of informative features. In addition to an in‐depth discussion of convolutional neural networks (CNNs) and transformers, we also highlight the strengths of methods such as support vector machines and evolved neural networks. We discuss the benefits of carefully curating training data and consider situations where less computationally expensive techniques are advantageous. This includes a comparison of popular model architectures and a guide to their implementation.
Trialkylphosphonium Oxoborate as C(sp3)−H Oxyanion Hole Catalyst for Diels‐Alder Reaction
Authors: Leung Vincent Ming‐Yau , Pook Chun‐Man , Chan Tsz‐Chun , Yeung Ying‐Yeung 
Published: December 2023

AbstractWe have developed a catalytic protocol for Diels‐Alder reaction using trialkylphosphonium oxoborates as oxyanion hole catalysts. The reaction can be operated under ambient conditions. Dienes could easily polymerize under acidic condition. Nonetheless, these acid‐sensitive substrates are compatible with the catalytic protocol and the reaction scope covers a wide range of substrates.
Genetic etiologies and diagnostic methods for congenital ventriculomegaly and hydrocephalus: A scoping review
Authors: Aragón Caroline , Robinson D'aviyan , Kocher Megan , Barrick Katie , Chen Lihsia , Zierhut Heather 
Published: December 2023

AbstractBackgroundCongenital hydrocephalus (CH) is a life‐threatening neurological condition that results from an imbalance in production, flow, or absorption of cerebrospinal fluid. Predicted outcomes from in utero diagnosis are frequently unclear. Moreover, conventional treatments consisting primarily of antenatal and postnatal surgeries are often unsuccessful, leading to high mortality rates. Causes of CH can range from secondary insults to germline pathogenic variants, complicating diagnostic processes and treatment outcomes. Currently, an updated summary of CH genetic etiologies in conjunction with clinical testing methodologies is lacking. This review addresses this need by generating a centralized survey of known genetic causes and available molecular tests for CH.MethodsThe scoping review protocol was registered with the Open Science Framework and followed the Arksey and O'Malley framework and the Joanna Briggs Institute methodology. The Preferred Reporting Items for Systematic reviews and Meta‐Analyses extension for Scoping Reviews (PRISMA‐ScR) was utilized to define search guidelines and screening criteria.ResultsOur survey revealed a high number of genetic etiologies associated with CH, ranging from single gene variants to multifactorial birth defects, and additionally uncovered diagnostic challenges that are further complicated by changes in testing approaches over the years. Furthermore, we discovered that most of the existing literature consists of case reports, underscoring the need for studies that utilize CH patient research cohorts as well as more mechanistic studies.ConclusionsThe pursuit of such studies will facilitate novel gene discovery while recognizing phenotypic complexity. Addressing these research gaps could ultimately inform evidence‐based diagnostic guidelines to improve patient care.
Detection of Multiple Antibiotic Residues in Turkish Pine and Blossom Honeys Using LC–MS/MS Method
Authors: Gün Ramazan , Dursun İnan , Arıcı Buket , Saraç Yasemin 
Published: December 2023

AbstractDue to the high demand for honey, beekeepers often feed the bees with antibiotics to protect honeybees against illnesses; the determination of veterinary drugs and their residues in bee products especially in honey is gaining importance. In this study, commercially available 15 different brands, a total of 22 honey (14 blossoms and 8 pines) samples obtained from 5 chain supermarkets in the city of Bingöl and Diyarbakır, Turkey were analysed for 29 antibiotic residues. These antibiotics belong to 10 different categories, including tetracyclines, aminoglycosides, macrolides, sulfonamides, fluoroquinolones, benzimidazoles, anthelmintic, amphenicols, quinolines, and oxazolidines. For the qualitative and quantitative determination of the antibiotics, a triple quadrupole liquid chromatography‐tandem mass spectrometry (LC‐MS/MS) was used. A total of 10 out of 22 honey (8 blossom, 57.14 % and 2 pine, 25 %) samples were found to be positive for antibiotics. Among the tested antibiotics, tetracycline, dihydrostreptomycin, streptomycin, erythromycin, and sulfadimidine were detected in the honey samples. Dihydrostreptomycin and sulfadimidine were detected in 6 samples, erythromycin was determined in 4 samples, streptomycin was found in 2 samples, and lastly, tetracycline was detected only in one sample. The highest and the lowest concentrations of antibiotics detected in the samples were dihydrostreptomycin and erythromycin found at the amount of 992.58 μg/kg and 0.77 μg/kg respectively. The proposed method was validated with a limit of quantification (LOQ) and limit of detection (LOD) ranging between 0.42 and 3.22 μg /kg and 0.13–0.97 μg /kg respectively. Good linearities were also achieved ranging between R2=0.987 and 0.999.
Multiple liquid‐liquid extraction of dissolved compounds in immortelle hydrosol with four different solvents
Authors: Komnenić Andreja , Lazarević Zorica , Jovović Zoran , Šavikin Katarina , Pljevljakušić Dejan 
Published: December 2023

AbstractImmortelle, a revered Mediterranean medicinal plant, is celebrated for its potent essential oil renowned in the cosmetic industry for its skin‐enhancing properties. Yet, immortelle hydrosol, an often‐overlooked byproduct, holds promise in cosmetics due to its compatibility with polar active ingredients. This study investigates the chemical composition of immortelle hydrosol by employing liquid‐liquid extraction (LLE) to transfer volatile organic components into nonpolar solvents. Four solvents – chloroform, dichloromethane, hexane, and benzene – were assessed through ten consecutive extractions from industrially produced immortelle hydrosol. Quantification was achieved using GC analysis with tetradecane as an internal standard. Chloroform emerged as the most efficient solvent, yielding 2447.0 mg/L of volatile compounds, surpassing dichloromethane, hexane, and benzene. Key compounds in immortelle hydrosol included 3‐pentanone, 2‐methyl‐1‐butanol, and γ‐terpineol. Importantly, the study revealed that a portion of essential oil compounds persists in the hydrosol even after ten LLE cycles, with optimal results achievable in five extractions (~92 % in most cases).
The Potential of Molecular Electrocatalysis for Ammonia‐to‐Dinitrogen Conversion
Authors: Kostopoulos Nikolaos , Robert Marc , Sekretareva Alina 
Published: December 2023

AbstractElectrochemical ammonia oxidation reaction (eAOR) regains interest due to ammonia being an interesting alternative to hydrogen for fuel cell technologies. In the present review, we first discuss some of the most important findings on eAOR with solid catalysts, including mechanistic and feasibility aspects for practical implementation. We then examine the reports on molecular catalysis of eAOR that have recently emerged. We finally discuss immobilization strategies of these molecular catalysts, and discuss intrinsic advantages of those strategies, so as to guide the design of efficient catalytic systems able to compete with heterogeneous, solid catalysts.
A Temperature‐Tolerant Magnesium‐Ion Battery Using Ball Cactus‐like MgV2O4 as High‐Performance Cathode
Authors: Ding Qian , Han Tianli , Zhou Ting , Lin Xirong , Liu Jinyun 
Published: December 2023

AbstractSafe and high‐performance secondary batteries using for all‐climate conditions with different temperatures are highly required. Here, we develop a three‐dimensional ball cactus‐like MgV2O4 as cathode material for magnesium‐ion (Mg‐ion) batteries. After cycling 300 times, the capacity maintains 111.7 mAh g−1, while Coulombic efficiency stabilizes at about 100 %. Under temperatures of 45 °C and −5 °C, the capacities remain stable after 200 cycles. After three rounds of rate‐performance tests, the capacity keeps quite stable. It is ascribed to the ball cactus‐like morphology buffers the volumetric change during Mg2+ insertion/extraction, and provides sufficient pathways for ion diffusion, which has been verified by constant‐current intermittent titration technology. It is believed that the good performance enables the Mg‐ion batteries to have a all‐climate capability.
Physicochemical Features and Applicability of Newly Fabricated Phytopharmaceutical‐Loaded Hydrogel Alginate Microcarriers with Viscoelastic Polyelectrolyte Coatings
Authors: Szczęsna‐Górniak Weronika , Weżgowiec Joanna , Tsirigotis‐Maniecka Marta , Szyk‐Warszyńska Lilianna , Michna Aneta , Warszyński Piotr , Saczko Jolanta , Wilk Kazimiera A. 
Published: December 2023

AbstractThe design of novel polymeric carrier systems with functional coatings is of great interest for delivering various bioactive molecules. Microcapsules coated with polyelectrolyte (PE) films provide additional functionality and fine‐tuning advantages essential for controlled drug release. We developed hydrogel microcarriers coated with functional PE films with encapsulated substances of natural origin, resveratrol (RES), curcumin (CUR), and epigallocatechin gallate (EGCG), which have cytotoxic and chemopreventive properties. Alginate (ALG) based microparticles were loaded with phytopharmaceuticals using the emulsification method, and then their surface was modified with PE coatings, such as chitosan (CHIT) or poly(allylamine hydrochloride) (PAH). The morphology and mean diameter of microcarriers were characterised by scanning electron microscopy, encapsulation efficiency was determined by UV‐Vis spectroscopy, whereas the physicochemical properties of functional PE layers were studied using quartz crystal microbalance with dissipation monitoring and streaming potential measurements. The release profiles of active compounds from the hydrogel microparticles were described using the Peppas‐Sahlin model. The cytotoxic effect of designed delivery systems was studied by evaluating their impact on the proliferation, mitochondrial metabolic function, and lipid peroxidation level of 5637 human bladder cancer cells. The present work demonstrates that the physicochemical and biological features of fabricated microcarriers can be controlled by the type of encapsulated anti‐cancer agent and PE coating.
The importance of context (placebo effects) in conservative interventions for musculoskeletal pain: A systematic review and meta‐analysis of randomized controlled trials
Authors: Saueressig Tobias , Owen Patrick J. , Pedder Hugo , Tagliaferri Scott , Kaczorowski Svenja , Altrichter Adina , Richard Antonia , Miller Clint T. , Donath Lars , Belavy Daniel L. 
Published: December 2023

AbstractBackground and ObjectiveContextual effects (e.g. patient expectations) may play a role in treatment effectiveness. This study aimed to estimate the magnitude of contextual effects for conservative, non‐pharmacological interventions for musculoskeletal pain conditions. A systematic review and meta‐analysis of randomized controlled trials (RCTs) that compared placebo conservative non‐pharmacological interventions to no treatment for musculoskeletal pain. The outcomes assessed included pain intensity, physical functioning, health‐related quality of life, global rating of change, depression, anxiety and sleep at immediate, short‐, medium‐ and/or long‐term follow‐up.Databases and Data TreatmentMEDLINE, EMBASE, CINAHL, Web of Science Core Collection, CENTRAL and SPORTDiscus were searched from inception to September 2021. Trial registry searches, backward and forward citation tracking and searches for prior systematic reviews were completed. The Cochrane risk of bias 2 tool was implemented.ResultsThe study included 64 RCTs (N = 4314) out of 8898 records. For pain intensity, a mean difference of (MD: −5.32, 95% confidence interval (CI): −7.20, −3.44, N = 57 studies with 74 outcomes, GRADE: very low) was estimated for placebo interventions. A small effect in favour of the placebo interventions for physical function was estimated (SMD: −0.22, 95% CI: −0.35, −0.09; N = 37 with 48 outcomes, GRADE: very low). Similar results were found for a broad range of patient‐reported outcomes. Meta‐regression analyses did not explain heterogeneity among analyses.ConclusionThe study found that the contextual effect of non‐pharmacological conservative interventions for musculoskeletal conditions is likely to be small. However, given the known effect sizes of recommended evidence‐based treatments for musculoskeletal conditions, it may still contribute an important component.SignificanceContextual effects of non‐pharmacological conservative interventions for musculoskeletal conditions are likely to be small for a broad range of patient‐reported outcomes (pain intensity, physical function, quality of life, global rating of change and depression). Contextual effects are unlikely, in isolation, to offer much clinical care. But these factors do have relevance in an overall treatment context as they provide almost 30% of the minimally clinically important difference.