bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cannabis and children: risk mitigation strategies for edibles
Authors: Conerney Cathy , Steinmetz Fabian , Wakefield James , Loveridge Sam 
Published: February 2024

In the era of (re)legalisation of medicinal and recreational cannabis, accidental and intentional exposure to edibles, cannabis-infused food products, has increased substantially. However, there is particular concern regarding younger age groups. Most concerning is the increase in hospitalisations. According to a study by Myran et al. (1), provinces in Canada, where the sale of edibles is permitted, saw an increase in paediatric poisonings due to unintentional consumption of edibles. Similar trends have been observed in “legalised states” in the US, such as Colorado (2). The impact of using cannabis at an early age, but particularly the impact of accidental exposure to high THC quantities, may have negative mental or physical health outcomes. Whilst regulatory restrictions vary significantly from one legalised region to another, it is difficult to identify a best practice. The aim of this study is to identify and discuss new and existing risk mitigation strategies to give guidance to policymakers. Furthermore, practical aspects, such as compliance (e.g. audits by authorities), are discussed. It is noted that edibles have been around much longer than recent political attempts to regulate them.
In-situ ionized construction of PVDF/sodium polyacrylate-grafted-PVDF blend ultrafiltration membrane with stable anti-oil-fouling ability for efficient oil-in-water emulsion separation
Authors: Gao Shoujian , Liu Pingping , Jin Jian 
Published: February 2024

Traditional polymeric membranes usually suffer from serious oil fouling and quick decline of water flux when separating oil-in-water emulsions. In this work, we report the fabrication of the sodium polyacrylate (PAAS) blended polyvinylidene fluoride (PVDF) ultrafiltration membrane which behaves hydrophilicity, underwater low-oil-adhesive superoleophobicity and outstanding anti-oil-fouling ability even for viscous crude oil. The blend membrane was fabricated via a two-step method, including the nonsolvent-induced phase inversion of PVDF/polyacrylic acid-grafted-PVDF (PVDF/PAA-g-PVDF) blend membrane and the subsequent in-situ ionization of PAA into PAAS. The two-step method improves the affinity between the strong hydrophilic additive PAAS and the hydrophobic polymer matrix PVDF, thus endowing the blend membrane with long-term stable superwetting property for 1,100 days. The PVDF/PAAS-g-PVDF blend membrane can efficiently separate multiple emulsifier-stabilized oil-in-water emulsions with ultrahigh separation efficiency of 99.97% (the residual oil content in the filtrate is lower than 3 ppm after one-step separation) and high water flux of 350 L m-2 h-1 bar-1. The blend membrane also shows good cycling performance, and can be easily cleaned by water washing during several separation cycles of the crude oil-in-water emulsion. This work inspires a feasible route of fabricating stable anti-oil-fouling membranes for separation of emulsified oily water.
Gonad pathology, sex hormone modulation and vitellogenin expression in Chrysichthys nigrodigitatus from Lagos and Epe lagoons within the southern-lagoon system, Nigeria
Authors: Akangbe Olusola A. , Chukwuka Azubuike V. , Imiuwa Maurice E. , Adeogun Aina O. 
Published: February 2024

Introduction: Estrogenic chemicals in aquatic environments impact fish reproductive health, with vitellogenin protein levels serving as a crucial biomarker for xenoestrogen exposure. Limited knowledge exists on estrogenic effects in tropical environments, prompting an investigation into the influence of environmental estrogens on Chrysichthys nigrodigitatus in Lagos and Epe lagoons.Methods: A total of 195 fish samples underwent analysis for vitellogenin protein, sex hormones (testosterone and 17 β-estradiol), and gonad pathology in effluent-receiving areas of the specified lagoons.Results: Gonadal alterations were observed in male and female fish, including empty seminiferous tubules and distorted ovaries. Intersex occurred in 3.81% of Lagos and 3.33% of Epe. Testosterone levels were generally higher in females and males from both lagoons, while E2 levels were higher in females from both lagoons, with Lagos showing higher levels than Epe. Vtg levels were higher in males than females in Lagos samples but showed no significant difference in Epe samples.Discussion: Contaminant analysis revealed similar trends in metals (Hg, As, Cr) and phthalates (DEHP, DBP, DEP) in both sexes in the Epe population. Multivariate depictions from the PCA showed sex-specific patterns of metal uptake (Cd) in male fishes at the Lagos Lagoon. The positive association between higher pH loadings and metal and DBP levels in sediment at the Lagos lagoon suggests the influence of higher alkalinity in lower bioavailability of contaminants.Conclusion: Endocrine disrupting effects were observed in male and female Chrysichthys nigrodigitatus in Lagos and Epe lagoons populations, with notable differences in hormone and contaminant concentrations between the two lagoon systems. Identification of specific contaminants and their spatial and temporal trends can inform targeted management and remediation efforts to protect and restore these valuable aquatic ecosystems.
An Integrated Investigation of the Relationship between Two Soil Microbial Communities (Bacteria and Fungi) and Chrysanthemum Zawadskii (Herb.) Tzvel. Wilt Disease
Authors: Wu Chao , Peng Juan , Song Tingting 
Published: February 2024

Chrysanthemum wilt is a plant disease that exerts a substantial influence on the cultivation of Chrysanthemum zawadskii (Herb.) for tea and beverage production. The rhizosphere microbial population exhibits a direct correlation with the overall health of plants. Therefore, studying the rhizosphere microbial community of Chrysanthemum zawadskii (Herb.) Tzvel. is of great significance for finding methods to control this disease. This study obtained rhizosphere soil samples from both diseased and healthy plant individuals and utilized high-throughput sequencing technology to analyze their microbial composition. The results showed that the rhizosphere microbial diversity decreased significantly, and the microbial community structure changed significantly. In the affected soil, the relative abundance of pathogenic microorganisms such as rhizospora and Phytophthora was greatly increased, while the relative abundance of beneficial microorganisms such as antagonistic fungi and actinomyces was greatly decreased. In addition, this study also found that soil environmental variables have an important impact on plant resistance; the environmental factors mainly include soil properties, content of major microorganisms, and resistance characteristics of samples. Redundancy analysis showed that the drug-resistant population had a greater impact on the 10 species with the highest abundance, and the environmental factors were more closely related to the sensitive population. In the fungal community, the resistant sample group was more sensitive to the influence of environmental factors and high-abundance fungi. These findings provide a theoretical basis for improving microbial community structure by optimizing fertilization structure, thus affecting the distribution of bacteria and fungi, and thus improving the disease resistance of chrysanthemum. In addition, by regulating and optimizing microbial community structure, new ideas and methods can be provided for the prevention and control of chrysanthemum wilt disease.
Metabolites from Streptomyces aureus (VTCC43181) and Their Inhibition of Mycobacterium tuberculosis ClpC1 Protein
Authors: Tran Thao Thi Phuong , Huynh Ni Ngoc Thi , Pham Ninh Thi , Nguyen Dung Thi , Tran Chien Van , Nguyen Uyen Quynh , Ho Anh Ngoc , Suh Joo-Won , Cheng Jinhua , Nguyen Thao Kim Nu , Tran Sung Van , Nguyen Duc Minh 
Published: February 2024

Tuberculosis is one of the most common infectious diseases in the world, caused by Mycobacterium tuberculosis. The outbreak of multiple drug-resistant tuberculosis has become a major challenge to prevent this disease worldwide. ClpC1 is a Clp ATPase protein of Mycobacterium tuberculosis, functioning as a chaperon when combined with the Clp complex. ClpC1 has emerged as a new target to discover anti-tuberculosis drugs. This study aimed to explore the ClpC1 inhibitors from actinomycetes, which have been known to provide abundant sources of antibiotics. Two cyclic peptides, including nocardamin (1), halolitoralin A (3), and a lactone pleurone (2), were isolated from the culture of Streptomyces aureus (VTCC43181). The structures of these compounds were determined based on the detailed analysis of their spectral data and comparison with references. This is the first time these compounds have been isolated from S. aureus. Compounds 1–3 were evaluated for their affection of ATPase activity of the recombinant ClpC1 protein. Of these compounds, halolitoralin A (1), a macrocyclic peptide, was effective for the ATPase hydrolysis of the ClpC1 protein.
Rancangan Sistem Informasi Pengelolaan Perpindahan Peserta Didik
Authors: Sukmana Esha Indra , Davied Jaradot Mangihut , Khadafi Dwi , Khadafi Mohammad Azmi , Nuris Nuzuliarini 
Published: February 2024

Pendidikan adalah suatu kegiatan pembelajaran didapatkan oleh semua manusia sehingga dapat membuat manusia tersebut memahami, mengerti dan dapat membuat manusia berpikir lebih dewasa dimana manusia yang sedang menempuh pendidikan disebut peserta didik. Perpindahan peserta didik merupakan proses perpindahan siswa dari sekolah anak usia dini sampai ke jenjang sekolah menengah atas pada sekolah asal ke sekolah yang dituju. Pada prosesnya banyak sekali hambatan yang terdapat dalam memberikan informasi mengenai penayangan daya tampung peserta didik setiap sekolah, proses pengajuan perpindahan, maupun pelaporan perpindahan peserta didik dan tidak adanya aplikasi mutasi masuk/keluar peserta didik. Berdasarkan permasalahan tersebut maka diperlukan membangun sebuah sistem informasi pengelolaan perpindahan peserta didik berbasis web dan dirancang dengan menggunakan model RAD dalam pengembangan perangkat lunak. Tujuan dibangunnya aplikasi untuk mampu memberi informasi secara cepat, tepat, dan akurat tentang jadwal serta daya tampung peserta didik pada setiap sekolah dan mempermudah dalam melakukan proses dan pengelolaan perpindahan peserta didik masuk/keluar atau mutasi. Aplikasi yang dihasilkan dapat dimanfaatkan dengan baik dalam pendataan sehingga mengurangi penumpukan berkas dari mutasi peserta didik.
Keakuratan FNAB pada Limfadenitis Tuberkulosis di Kelenjar Getah Bening Leher di Manado
Authors: Ijong Jessie I , Lumintang Nico 
Published: February 2024

Abstract: Tuberculous lymphadenitis is the most common type of extrapulmonary tuberculosis (TB). Fine needle biopsy aspiration (FNAB) is an initial diagnostic method to evaluate lymph node enlargement in the neck This study aimed to evaluate the accuracy of FNAB in tuberculous lymphadenitis in neck lymph nodes in Manado. This was is a retrospective and descriptive study using medical record data on the use of FNAB examination in patient with a history of lymph node enlargement years 2017-2018. The results obtained 160 FNAB samples with clinical lymph node enlargement in the neck; 86 samples (54%) with TB lymphadenitis, nine samples (6%) were suspected as TB lymphadenitis, and 65 samples (40%) were not TB lymphadenitis The incidence in women (61%) was higher than in men (39%). TB lymphadenitis was most common in women aged <19 years and men aged 20-30 years. In conclusion, FNAB remains an important option as one of the diagnostic supporting tools for lymph node enlargement especially to confirm the diagnosis of tuberculous lymphadenitis in the neck.
Keywords: fine needle biopsy aspiration; tuberculous lymphadenitis; cytopathological diagnosis

Abstrak: Limfadenitis tuberkulosis (TB) merupakan bentuk TB ekstrapulmoner yang tersering. Fine needle biopsy aspiration (FNAB) ialah metode diagnostik awal untuk mengevaluasi pembesaran kelenjar getah bening di leher. Penelitian ini bertujuan untuk mengetahui keakuratan FNAB pada limfadenitis tuberkulosis di kelenjar getah bening leher di Manado. Jenis penelitian ialah deskriptif retrospektif menggunakan data rekam medik penggunaan pemeriksaan FNAB pada pasien yang memiliki riwayat pembesaran kelenjar getah bening di leher di Laboratorium Patologi Anatomi RSUP Prof R. D. Kandou Manado.tahun 2017-2018. Hasil penelitian mendapatkan 160 sampel FNAB dengan klinis pembesaran pada leher; 86 sampel (54%) dengan hasil FNAB limfadenitis TB, sembilan sampel (6%) dicurigai sebagai limfadenitis TB, dan 65 sampel (40%) bukan limfadenitis TB. Kejadian pada perempuan (61%) lebih tinggi daripada laki-laki (39%). Limfadenitis TB tersering pada perempuan berusia <19 tahun dan laki-laki 20-30 tahun. Simpulan penelitian ini ialah sampai saat ini FNAB tetap menjadi pilihan sebagai salah satu alat penunjang diagnostik untuk evaluasi pembesaran kelenjar getah bening terutama dalam menentukan limfadenitis TB di leher.
Kata kunci: fine needle biopsy aspiration; limfadenitisis tuberculosis; diagnostik sitopatologi
Kualitas dan Masa Simpan Brownies Satin Berbasis Tepung Mocaf danTepung Ikan Patin
Authors: Kodriah Nur Rahmawati , Hastuti Widi 
Published: February 2024

Background : Anemia is one of the main problems experienced by many young women. The prevalence of anemia in adolescent girls (15-24 years) in 2018 is 32%. Efforts that can be made are by increasing the intake of iron sources especially animal food sources. Brownies become a distraction that is widely favored by the wider community. Utilization of mocaf flour and catfish flour as the main ingredient in the manufacture of brownie products will increase the nutritional value especially the iron content of the product. The purpose : of this study was to determine the quality and shelf life of satin brownies as a high-fer snack for young girls. Methods : Design of experimental research based on mocaf flour and catfish flour. A hedonic test was carried out by 30 panelists at the Nutrition Test Laboratory for the Department of Nutrition of the Poltekkes Ministry of Health, Bandung and the estimated shelf life using the Extend Storage Studies (ESS) method. The results : Organoleptic test results showed the highest level of panelist preference was at F2. Based on statistical tests found that there is an effect of the formulation on the aroma of F1 and F3 with a value of p = 0.015 and texture of F1 and F3 with a value of p = 0.016. The results of the calculation of the nutritional value of satin brownies compared with 10% of the AKG of female teenage snacks obtained 101% energy, 113% protein, 140% fat, 72% carbohydrate and 149% Fe. Shelf life of satin brownies at room temperature for 3 days. Suggestion : Based on the results of research it is necessary to do further research in the laboratory regarding the iron content contained in satin brownies
Determinan Pemberian Asi Ekslusif Ibu Menyusui di Puskesmas 7 Ulu Kota Palembang
Authors: Yusuf M , Sriwiyanti Sriwiyanti , Muzakar Muzakar , Eliza Eliza 
Published: February 2024

Latar Belakang: Di kota Palembang cakupan pemberian ASI ekslusif untuk tahun 2017 sebesar 72,76%. Cakupan di Kecamatan Seberang Ulu sebesar 66,15%. Kecamatan ini ada 3 (tiga) Puskesmas, cakupan yang terendah adalah Puskesmas 7 Ulu Palembang sebesar 43,9 %. Cakupan ini masih jauh di bawah target pencapaian pemberian ASI ekslusif Indonesia yaitu 80%. Untuk meningkatkan cakupan ASI ekslusif, dilakukan dengan mencari faktor determinan perilaku ibu dalam pemberian ASI ekslusif ibu menyusui di Puskesmas 7 Ulu Palembang. Diharapkan dengan diketahui penyebab perilaku ibu dalam pemberian ASI ekslusif dapat meningkatkan cakupan pemberian ASI ekslusif di daerah tersebut. Tujuan: Untuk mengetahui Determinan pemberian ASI ekslusif ibu menyusui di Puskesmas 7 Ulu Palembang. Metode: Menggunakan Cross Sectional. Sampel berjumlah 35 responden yang memilki bayi (0-6) bulan. Pengumpulan data dengan wawancara serta dokumentasi, dianalisis menggunakan uji chisquare. Hasil: Ada hubungan antara Sikap dengan pemberian ASI ekslusif. Tidak ada hubungan antara Pengetahuan, pekerjaan, pendidikan, jumlah anak, inisiasi menyusui dini, dan pertolongan melahirkan dengan pemberian ASI ekslusif. Manfaat: Dapat digunakan petugas kesehatan puskesmas 7 Ulu untuk meningkatkan capaian program pemberian ASI ekslusif di Kota Palembang, meningkatnya kesadaran ibu memberikan ASI ekslusif pada bayi.
Kata Kunci: ASI ekslusif , Ibu menyusui.
Daya Terima Flakes Tepung Bekatul dan Tepung Jagung Sebagai Makanan Selingan Tinggi Serat
Authors: Muliani Dian , Sartono Sartono , Yulianto Yulianto 
Published: February 2024

Background: Flakes are a form of ready-to-eat cereal product. In general, flakes are made from wheat flour or from starch such as tapioca flour. However, at this time innovation has been developed in the processing of flakes. Flakes with the addition of bran flour and corn flour which are rich in fiber are also very suitable for consumption as a diet food or an alternative snack for overweight teenagers.
Objective: To determine the acceptability of bran flour and corn flour flakes as high fiber snacks.
Method: Experimental method with non-factorial Completely Randomized Design (CRD). Using the Organoleptic Test with 25 panelists. Determination of nutritional value and fiber using proximate analysis and fiber analysis.
Results: The selected flakes formulation of bran flour and corn flour was F2 (30 grams of rice bran flour and 70 grams of corn flour) with an energy content of 403.61 Kcal, 8.5% protein, 6.91% fat, 76.84% carbohydrates. , 3.79% moisture content, 3.94% ash content, and 7.19% fiber in 100 g of flakes. Based on the Friedman test, there was no significant effect between the acceptance of bran flakes and corn flour on color (p = 0.251), taste (p = 0.006), aroma (p = 0.821), and texture (p = 0.553).
Conclusion: Flakes with the addition of rice bran flour and corn flour can be used as an alternative snack that is high in fiber.
Beberapa faktor yang berhubungan dengan keputusan Pembelian Susu Formula
Authors: Mardiana Mardiana , Pangesti Nindia Ayu , Yulianto Yulianto , Podojoyo Podojoyo , Eliza Eliza 
Published: February 2024

ABSTRACT

Background The purchase decision is one of the indications that indicates whether or not a product is accepted by consumers. Location determination based on data on the highest number of cases of malnutrition status (BB/U) in Palembang City, namely in the working area of the Nagaswidak Health Center with 370 cases.Objective: To determine the relationship between the price, nutritional knowledge, income level and advertising of milk with the decision to buy formula milk. Method: The study design was in the form of quantitative crosssectional with a sample of 32 mothers who had toddlers aged between 1 to 3 years using Lemeshow calculations plus a 10% reserve selected using purposive sampling techniques. Data collection on formula milk purchasing decisions, prices, nutritional knowledge, income levels, and direct milk advertising is using questionnaires, observations and by taking anthropometric measurements. The data were analyzed univariately and bivariately using the Chi-Square test. Results: The results showed that there was a relationship between price (p<0.001) and income level (p = 0.03) with purchasing decisions and there was no relationship between nutritional knowledge (p = 0.357) and milk advertising (p = 0.169) with consumer decisions.Conclusion: It was concluded that the price of milk and the income of a person contain a positive relationship with the decision to purchase milk and the level of knowledge of the mother is quite an important factor towards the decision to purchase a food.
Gambaran Pengetahuan Gizi dan Sikap Remaja Putri terhadap Kepatuhan Mengkonsumsi Tablet Tambah Darah di SMA Negeri 6 Palembang
Authors: Rosenda Caroline , Wiyanti Sri , Siregar Afriyana 
Published: February 2024

Background : Young women are a group that is prone to anemia because they are easily influenced by the social environment including food selection.9) The impact on young women is a decrease in learning concentration so that they can experience bleeding before and during childbirth.
Purpose of the study was to determine the picture of nutritional knowledge and attitudes of adolescent girls towards adherence to taking blood-added tablets at SMA Negeri 6 Palembang.
Method is discriptive with a cross sectional design. The sample used was 70 young women in class XI MIPA and Social Studies. For sampling techniques using proportional stratified random sampling and simple random sampling with analysis data using univariate and bivariate analysis.
Results: this study showed that 64 people (91.4%) of adolescent girls with non-compliance knowledge and 55 women (78.6%).
Conclusion: From the cross-table analysis, adherence of adolescent girls taking TTD (Blood Added Tablets) both has nutritional knowledge as many as 15 people (23.4%) and admonition of adolescent girls with good attitudes as many as 11 people (55%) in taking blood added tablets.
Suggestion: based on the results of this study, it is hoped that adolescent girls realize that taking TTD can minimize anemia and as a preparation for the future before becoming a mother.
External Faktor Eksternal Berpengaruh dengan Sisa Makanan (Nabati dan Sayur) pada Diet Makanan Biasa dan Lunak di RSUD Harapan dan Doa Kota Bengkulu
Authors: Putricia Dita , Yuliantini Emy , Wahyudi Anang 
Published: February 2024

Background: Research data from Harapan and Doa Hospital in 2019 showed that the remaining vegetable protein increased to 27.61% and vegetables 56%. This rate still exceeds the minimum hospital service rate for food waste, which is ≤ 20%. Purpose of the study was to examine external factors that affect the remaining plant and vegetablefood in the diet of ordinary and soft foods as well as an overview of external factors at Harapan and Doa Hospital, Bengkulu City.
Method: Cross sectional design with the type of analytic survey research used in this study with a sample of 34 respondents.
Results: In the remaining vegetable side dishes, timeliness of feeding with a p-value of 0.648, food taste (0.182) and the attitude of the serving staff (0.487) which means that H0 failed to be rejected (> 0.05). For leftover vegetable food, the timeliness of feeding with a p-value of 0.647, the atmosphere of the caring environment (0.541) and the attitude of the serving staff (1.000) which means that H0 failed to be rejected (> 0.05).
Conclusion: There is a relationship between the appearance of food and the consumption of food from the outsidewith vegetable and vegetable side dishes.es.