bluuebunny/crossref_metadata_2025_split huggingface dataset:
Thermotherapy using magnetic nanoparticles combined with external radiation in an orthotopic rat model of prostate cancer
Authors: Johannsen Manfred , Thiesen Burghard , Gneveckow Uwe , Taymoorian Kasra , Waldöfner Norbert , Scholz Regina , Deger Serdar , Jung Klaus , Loening Stefan A. , Jordan Andreas 
Published: August 2005

AbstractBACKGROUNDWe evaluated the effects of thermotherapy using magnetic nanoparticles, also referred to as magnetic fluid hyperthermia (MFH), combined with external radiation, in the Dunning model of prostate cancer.METHODSOrthotopic tumors were induced in 96 male Copenhagen rats. Animals were randomly allocated to eight groups, including controls and groups for dose‐finding studies of external radiation. Treatment groups received two serial thermotherapy treatments following a single intratumoral injection of magnetic fluid or thermotherapy followed by external radiation (10 Gy). On day 20, after tumor induction, tumor weights in the treatment and control groups were compared and iron measurements in selected organs were carried out.RESULTSMean maximal and minimal intratumoral temperatures obtained were 58.7°C (centrally) and 42.7°C (peripherally) during the first thermotherapy and 55.4°C and 42.3°C, respectively, during the second of two treatment sessions. Combined thermotherapy and radiation with 20 Gy was significantly more effective than radiation with 20 Gy alone and reduced tumor growth by 87.5–89.2% versus controls. Mean iron content in the prostates on day 20 was 87.5% of the injected dose of ferrites, whereas only 2.5% was found in the liver.CONCLUSIONSAn additive effect was demonstrated for the combined treatment at a radiation dose of 20 Gy, which was equally effective in inhibiting tumor growth as radiation alone with 60 Gy. Serial heat treatments were possible without repeated injection of magnetic fluid. The optimal treatment schedules of this combination regarding temperatures, radiation dose, and fractionation need to be defined in further experimental studies. © 2005 Wiley‐Liss, Inc.
Effect of increasing ratio of estrogen: Androgen on proliferation of normal human prostate stromal and epithelial cells, and the malignant cell line LNCaP
Authors: King Keith J. , Nicholson Helen D. , Assinder Stephen J. 
Published: August 2005

AbstractBACKGROUNDChanges in steroid ratios seen in the aging male are thought to promote prostate disease. The aims of this study were to compare the effects of varied ratios of steroids on growth of normal stromal and epithelial cell isolates, and the prostate cancer cell line, LNCaP.METHODSThe effect of altered steroid ratios on cell proliferation of normal stromal (PrSC) and epithelial (PrEC) prostate cells, and the malignant cell line, LNCaP, were assessed.RESULTSIncreasing the ratios of both estrogen:dihydrotestosterone (DHT) and DHT:estrogen, stimulated PrSC proliferation, with increasing estrogen:DHT having the greatest effect. LNCaP proliferation was increased significantly by both steroids, but altered ratios had no additional effect. PrEC proliferation was unaffected when cells were grown alone, despite presence of androgen receptors (AR) and estrogen receptors (ER). When grown in co‐culture PrEC cell proliferation was significantly increased by treatments.CONCLUSIONSPrSC proliferation is stimulated by an increasing ratio of estrogen:androgen. Proliferation of normal epithelial cells is stimulated as a result of an indirect action of steroids mediated by stromal cells. Malignant prostate cancer cells have an altered response in comparison. © 2005 Wiley‐Liss, Inc.
A Study on inhibitory effects of Sığla tree (Liquidambar orientalis Mill. var. orientalis) storax against several bacteria
Authors: Sağdıç Osman , Özkan Gülcan , Özcan Musa , Özçelik Sami 
Published: August 2005

AbstractIn this study, Sığla (Liquidambar orientalis Mill.) storax (styrax) was investigated for antibacterial activity against Aeromonas hydrophila, Bacillus amyloliquefaciens, B. brevis, B. cereus, B. megaterium, B. subtilis, Corynebacterium xerosis, Enterobacter aerogenes, Enterococcus faecalis, Escherichia coli, E. coli O157:H7, Klebsiella pneumoniae, Listeria monocytogenes, Micrococcus luteus, Mycobacterium smegmatis, Proteus vulgaris, Pseudomonas aeruginosa, P. fluorescens, Staphylococcus aureus and Yersinia enterocolitica. The storax was dissolved in absolute ethanol and was tested at concentrations of 10.0%, 1.0%, 0.4%, 0.2% and 0.1%. Pure ethanol was used for the control. The antibacterial activity of the Sığla storax was determined by using the agar diffusion method. The growths of A. hydrophila, B. amyloliquefaciens, B. megaterium, E. coli, E. coli O157:H7, L. monocytogenes and Y. enterocolitica were not inhibited by any of the concentrations of Sığla storax. The results showed that Sığla storax has antibacterial activity against many bacteria at concentrations of 10.0% and against some bacteria at concentrations of 1.0%, 0.4% and 0.2%. Copyright © 2005 John Wiley & Sons, Ltd.
Synthesis, Characterization, Molecular Structure, and Electrochemistry of a New Ferrocenoyl Derivative
Authors: Matesanz Ana I. , Cuadrado Isabel , Mosa Jadra , García Irene , Souza Pilar 
Published: August 2005

AbstractA new organometallic compound containing a heterocyclic amine linked to the ferrocenoyl moiety was synthesized and characterized by elemental analysis (C, H, N), mass spectrometry, IR and 1HNMR spectroscopy. Its crystal and molecular structure was determined by X‐ray diffraction methods. This compound crystallizes in the monoclinic P21 space group, a = 5.80260(10), b = 9.24160(10), c = 12.3510(2) Å, β = 92.8200(10)° and Z = 2. An interesting feature of the crystal structure is the presence of an intermolecular non‐classical hydrogen bonding interaction between a cyclopentadienyl hydrogen atom and a carbonyl oxygen group. The electrochemical behaviour of this compound is characterized by the reversible one‐electron oxidation of the ferrocene moiety.
A First Principles Study of Hydrogen Storage in NaAlH4‐Related Complex Hydrides
Authors: Arroyo y de Dompablo M. E. , Ceder G. 
Published: August 2005

AbstractWe have applied first principles computations to predict the properties of complex hydrides related to the alanate NaAlH4, a very promising class of systems for reversible hydrogen storage. The effect of partial substitution on the Na site (by Li or K), and on the Al site (by B or Ga) on the thermodynamic stability of NaAlH4 and its decomposition product Na3AlH6 is investigated and evaluated by means of qualitative van't Hoff plots. From the calculated results we infer that the most promising improved hydrides are Na1−xLixAl1−yByH4, obtained by a double substitution on the Na and on the Al sites of NaAlH4.
Dinuclear Cobalt(III) Complexes Showing a Co2O2 Metallacycle
Authors: Fondo Matilde , Deibe Ana M. García , Ocampo Noelia , Bermejo Manuel R. , Sanmartín Jesús 
Published: August 2005

AbstractThe heptadentate Schiff base H3L reacts with cobalt(II) acetate in methanol to form the discrete dinuclear complex Co2L(OAc)2(OMe)(H2O)2 (1·2H2O). The reaction of 1·2H2O with NMe4OH·5H2O in methanol gives rise to displacement of the acetate by methanolate groups, yielding Co2L(OMe)3(H2O) (2·1H2O). Recrystallizations of the Schiff base, 1·2H2O and 2·H2O in different solvents, produce single crystals of H3L, 1·2.5H2O and 2·2MeOH, respectively. The crystal structures of 1·2.5H2O and 2·2MeOH show the cobalt atoms double bridged by and endogenous phenol oxygen atom and an exogenous methanolate oxygen donor, giving rise to Co2O2 cores with Co···Co distances of ca. 2.87 Å.
Copper(II), Cobalt(II), and Nickel(II) Complexes of two Novel Pyridine‐derived Macrocyclic Ligands bearing o‐ and pNitrobenzyl Pendant Groups
Authors: Martínez Jesús , Bastida Rufina , Macías Alejandro , Valencia Laura , Vicente Manuel 
Published: August 2005

AbstractThe pendant‐armed ligands L1 and L2 were synthesized by N‐alkylation of the four secondary amine groups of the macrocyclic precursor L using o‐nitrobenzylbromide (L1) and p‐nitrobenzylbromide (L2). Nitrates and perchlorates of CuII, NiII and CoII were used to synthesize the metal complexes of both ligands and the complexes were characterized by microanalysis, MS‐FAB, conductivity measurements, IR and UV‐Vis spectroscopy and magnetic studies. The crystal structures of L1, [CuL1](ClO4)2·CH3CN·H2O, [CuL2](ClO4)2·6CH3CN, [CuL2][Cu(NO3)4]·5CH3CN·0.5CH3OH and [NiL2](ClO4)2·3CH3CN·H2O were determined by single crystal X‐ray crystallography. These structural analysis reveal the free ligand L1, three mononuclear endomacrocyclic complexes {[CuL1](ClO4)2·CH3CN·H2O, [CuL2](ClO4)2·6CH3CN and [NiL2](ClO4)2·3CH3CN·H2O} and one binuclear complex {[CuL2][Cu(NO3)4]·5CH3CN·0.5CH3OH} in which one of the metals is in the macrocyclic framework and the other metal is outside the ligand cavity and coordinated to four nitrate ions.
Synthesis and Characterization of [(1,4‐diamine)dichloro]platinum(II) Compounds Preliminary Studies on their Biological Activity
Authors: de Mier‐Vinué Jordi , Montaña Ángel M. , Moreno Virtudes , Prieto María J. 
Published: August 2005

AbstractTwo 1,4‐diamine ligands were synthesized having 1,2‐bis(aminomethyl)‐cyclohexane and 1,2‐bis(aminomethyl)‐benzene structures. The two ligands have different electron density in the six‐membered ring: a cyclohexane versus a phenyl ring. The organic synthesis of the ligands was carried out by synthetic pathways of seven and four steps, respectively, starting from 1,2,3,6‐tetrahydrophthalic anhydride and diethyl phthalate. The coordination of platinum to these ligands afforded platinum(II) complexes which are analogue to the clinical drug cisplatin but form a seven‐membered chelate ring. The interaction of the platinum compounds with DNA was studied in order to know the relationship between the electron density of ligands and their capability to chelate DNA, by using three techniques: Circular Dichroism, Agarose Gel Electrophoresis and Atomic Force Microscopy. The degree of interaction of both compounds with DNA was slightly different, but both complexes showed a cisplatin‐like behaviour and are promising candidates to follow an extensive study of their cytotoxic activity.
Tetra(3‐methoxypropionato)diruthenium(II, III) Units: Supramolecular Organization in the Complex [Ru2(μ‐O2CCH2CH2OMe)4(H2O)2]BF4
Authors: Barral M. Carmen , González‐Prieto Rodrigo , Jiménez‐Aparicio Reyes , Priego J. Luis , Royer Elia C. , Torres M. Rosario , Urbanos Francisco A. 
Published: August 2005

AbstractThe synthesis and characterization of Ru2Cl(μ‐O2CCH2CH2OMe)4 (1), [Ru2(μ‐O2CCH2CH2OMe)4(H2O)2]BF4 (2), PPh4[Ru2Cl2(μ‐O2CCH2CH2OMe)4] (3), (PPh4)2[Ru2Br2(μ‐O2CCH2CH2OMe)4]NO3 (4), and (PPh4)2[Ru2I2(μ‐O2CCH2CH2OMe)4]I0.5(NO3)0.5 (5), are described. The structure of complexes 2–5 was established by single crystal X‐ray diffraction. All complexes show a diruthenium(II, III) unit bridged by four 3‐methoxypropionate ligands. The cationic complex 2 have two axially coordinated water molecules, with a Ru–Ru bond distance of 2.2681(12) Å. This complex shows a supramolecular two‐dimensional organization across hydrogen bonded between the axial water molecules and two methoxy groups of adjacent diruthenium units. The metal‐metal bond lengths, in the anionic complexes 3, 4, and 5, are 2.3039(5), 2.3077(6), and 2.3115(8) Å, respectively. These distances are longer than the observed in compound 2. In the anionic complexes, the axial positions of the diruthenium units are occupied by two halide ligands. Complexes 3–5 have PPh4+ cations as counterion, although 4 and 5 are double salts with PPh4NO3 and PPh4I0.5(NO3)0.5, respectively.All compounds have been also characterized by elemental analysis, magnetic measurements, and spectroscopic techniques.
Mixed‐ligand Complexes with 2,6‐Pyridinedicarboxylato(2‐) and 4,7‐Diphenyl‐1,10‐Phenanthroline Ligands, [MII(pdc)(DPphen)(H2O)]·H2O (M = Co or Cu). Synthesis, Crystal Structures and Properties
Authors: Brandi‐Blanco María Pilar , Choquesillo‐Lazarte Duane , González‐Pérez Josefa María , Castiñeiras Alfonso , Niclós‐Gutiérrez Juan 
Published: August 2005

AbstractIso‐type [MII(pdc)(DPphen)(H2O]·H2O compounds (M = Co or Cu, pdc = 2,6‐pyridinedicarboxylato(2‐) ligand and DPphen = 4,7‐diphenyl‐1,10‐Phenanthroline) were synthesized and studied by X‐ray diffraction, thermal and spectral methods. The N,N′‐equatorial bidentate DPphen‐copper(II) chelation imposes a mer‐N(equatorial)+O2(apical) conformation to pdc in the coordination polyhedron (type 4+1+1). In the Co(II) derivative, the coordination is of type 1+2+2+1 because of a lesser Jahn‐Teller distortion. In the crystals, π,π‐interligand interactions between phen ligands connect the complex molecules in multi‐stacked chains. Aqua···O(carboxyl) H‐bonding interactions reinforce the stacked chains and build double chains in 1D supramolecular structures parallel to the a axis. Non coordinated water connect these structures by H‐bonds.
Electrochemical Synthesis and Characterization of Nickel(II) Complexes with N‐2‐Pyridyl‐sulfonamide Ligands
Authors: Beloso Inmaculada , Pérez‐Lourido Paulo , Castro Jesús , García‐Vázquez José A. , Romero Jaime 
Published: August 2005

AbstractHeteroleptic nickel(II) complexes [NiL2L′] of a series of monoanionic and potentially bidentate N‐2‐pyridyl‐sulfonamide ligands [HL] and 2,2′‐bipyridine or 1,10‐Phenanthroline (L′) have been prepared by electrochemical oxidation of a nickel anode in an acetonitrile solution of the ligands. The complexes have been characterized by microanalysis, IR and electronic spectroscopy, magnetic measurements and LSI mass spectrometry. The crystal structure of [Ni(Ms6mepy)2(bipy)] has been determined by x‐ray diffraction and shows the metal in an octahedral NiN6 environment. Octahedral structures are also proposed for the other complexes with the N‐2‐pyridyl‐sulfonamide ligands acting as N,N′ or N, O bidentate systems, depending on the position of the methyl substituent on the pyridine ring.
Synthesis and Characterization of Spinel‐Type Gallia‐Alumina Solid Solutions
Authors: Areán C. Otero , Delgado M. Rodríguez , Montouillout V. , Massiot D. 
Published: August 2005

AbstractBy precipitation with ammonia of ethanolic solutions containing the appropriate proportions of gallium and aluminium nitrate, following by calcination of the resulting gels at 773 K, mixed Ga2O3/Al2O3 oxides having Ga:Al ratios of 9:1, 4:1, 1:1, 1:4 and 1:9 were obtained. Powder X‐ray diffraction showed that these mixed metal oxides form a series of solid solutions having the spinel‐type structure; also shown by γ‐Al2O3 and γ‐Ga2O3. The specific surface area (determined by nitrogen adsorption at 77 K) was found to range from 160 m2 g−1 for the mixed oxide having Ga:Al = 9:1 up to 370 m2 g−1 for that having Ga:Al = 1:9. High resolution MAS NMR showed that Ga3+ and Al3+ ions occur at both tetrahedral and octahedral sites in the spinel‐type structure of the mixed metal oxides, although there is a preferential occupation of tetrahedral sites by Ga3+ ions. A proportion of penta‐coordinated Al3+ ions was also found. IR spectra of carbon monoxide adsorbed at 77 K showed that the mixed metal oxides have a considerable Lewis acidity, related mainly to tetrahedrally coordinated metal ions exposed at crystal surfaces. The characteristic infrared absorption band of coordinated (adsorbed) CO appears in the range 2205–2190 cm−1, and its peak wavenumber is nearly independent of Ga:Al ratio in the mixed gallia‐alumina oxides.
Chromium(IV) Stabilisation in New Ceramic Matrices by Coprecipitation Method: Application as Ceramic Pigments
Authors: Monrós G. , Pinto H. , Badenes J. , Llusar M. , Tena M. A. 
Published: August 2005

AbstractIn this paper the stabilization of Cr4+ in new ceramic matrices as willemite Zn2SiO4 and galium‐gadolinium garnet GGG (Gd3Ga5O12) is studied and compared with the chromium‐sphene ceramic pigment using the traditional solid reaction and an unconventional coprecipitation method.The chromate amount etched from the powders using CrIII and CrVI precursors on ceramic and coprecipitation routes are analysed in order to evaluate the environmental impact on the waste water. Cr‐willemite and codoped Ca, Cr‐GGG produces solid solutions of Cr4+ ion occupying tetrahedral and dodecahedral sites, respectively, while Cr4+ into sphene lattice occupies octahedral sites. Cr‐willemite are stable when used as ceramic pigment in habitual tile glazes but Cr‐GGG unstabilses and produces green colour associated to Cr3+ solved in the glaze. Coprecipitate powders are more reactive than ceramic powders but in Cr‐GGG stabilizes the metastable Ca3Cr2O8 oxide. Chromate amount in washing hot water are not dependent of the chromium precursor but depends of the allowed reactivity level and the reaction media.
Synthesis and Electrochemical Study of Antifluorite‐type Phases in the Li‐M‐N‐O (M = Ti, V) Systems
Authors: Cabana J. , Mercier C. , Gautier D. , Palacín M. R. 
Published: August 2005

AbstractAntifluorite‐type phases have been prepared in the Li‐M‐N‐O (M = Ti, V) systems by solid state reaction under nitrogen starting from mixtures of lithium nitride, different amounts of lithium oxide and the transition metal nitride. The two series of samples obtained can be formulated as Li5TiN3 · xLi2O and Li7VN4 · xLi2O solid solutions. X‐ray diffraction data indicate that, as the amount of oxygen increases, the superstructure peaks decrease in intensity without changing their position, whereas the peaks corresponding to the simple anti‐fluorite structure increase. Thus, samples with low oxygen content are a mixture of two phases: the corresponding ternary nitride (either Li5TiN3 or Li7VN4) and the quaternary oxinitride with a disordered antifluorite structure and hence structural disorder does not seem to be induced progressively, as previously believed. In agreement with previous studies, a decrease of the cell parameter with oxygen content is observed in both solid solutions. Even though no deintercalation/intercalation reactions were expected (no cationic vacancies exist in the sample and the transition metals are present in their highest oxidation states) an evaluation of the electrochemical performances of the samples vs. metallic lithium was done to test the possibility of conversion reactions taking place. However, none of them showed any electroactivity.
Mixed‐ligand Copper(II) Complexes with N‐isopropyl‐iminodiacetato(2‐) and C‐phenyl‐imidazole Ligands. Crystal Structures of H2iPIDA, [Cu(iPIDA)(H2ϕim)(H2O)]·3H2O and [Cu(iPIDA)(H5ϕim)]n
Authors: Rojas‐González Perla Xochitl , Brandi‐Blanco María Pilar , Castiñeiras Alfonso , Choquesillo‐Lazarte Duane , González‐Pérez Josefa María , Niclós‐Gutiérrez Juan 
Published: August 2005

AbstractThe crystal of the N‐isopropyl‐iminodiacetic acid (1) consists of a 3D H‐bonded framework where the zwitterion (H2iPIDA±) is intra‐stabilized by one N+‐H···O interaction and both carboxyl are half‐protonated and involved in linear O‐H···O inter‐molecular bridges of 2.46 Å. The mixed‐ligand complexes [Cu(iPIDA)(H2ϕim)(H2O)]·3H2O (2) and [Cu(iPIDA)(H5ϕim)]n (3) have also been synthesized and studied by thermal, spectral, magnetic and X‐ray diffraction methods. Both complexes exhibit a square base pyramidal coordination, type 4+1. Compound 3 is the less steric hindered 'remote' isomer, with H5ϕim instead of H4ϕim.
Interaction of Mn(acac)3 with Asymmetrical Schiff Base Ligands containing an Amido Group
Authors: González‐Noya Ana M. , Fernández M. Isabel , Maneiro Marcelino , Rodríguez M. Jesús , Pedrido Rosa , Vázquez Miguel , Bermejo Manuel R. 
Published: August 2005

AbstractInteraction of asymmetrical Schiff base ligands H3Ln [where H3Ln are substituted 3–aza–4–(2–hydroxyphenyl)–N– (2–hydroxyphenyl)but–3–enamide] with Mn(acac)3 (acac = acetylacetonate) has been investigated. Two different type of manganese(III) complexes have been obtained depending on the nature of the substituents on the ligand. We have found that ligands containing donor substituents drives to the formation of two different kinds of complexes from the same reaction: Mn(Ln)(H2O)x (1a–5a) and [Mn(HLn)(acac)](H2O)y (1b–5b) (where Ln and HLn signify the ligand in its trianionic and dianionic form, respectively). However, when the substituents are electron withdrawing or poor donor only compounds of the type [Mn(HLn)(acac)](H2O)y (6–10) are obtained. All these compounds have been characterized by elemental analyses, IR and 1H NMR spectroscopy, FAB mass spectrometry, magnetic measurements and molar conductivities. The electrochemical behaviour of these complexes has also been studied.
Biological Activity of Flavonoids Copper Complexes
Authors: González‐Álvarez Marta , Alzuet Gloria , García‐Giménez José Luis , Macías Benigno , Borrás Joaquín 
Published: August 2005

AbstractThree flavonoid copper(II) complexes Cu2(quercetin)(CH3COO)3(CH3OH) (1), Cu(anthrarufin)(CH3COO)·1/2H2O (2) and Cu(naringin)(OCH3)(CH3OH)2 (3) have been synthesized and characterized by elemental analysis, IR, electronic absorption and EPR (X‐band) spectroscopy. The complexes have a strong protective action over the Δsod1 mutant of S. cerevisiae against reactive oxygen radicals generated by an external source of free radicals (H2O2 or the superoxide‐generating, menadione). On the other hand, the complexes cleave DNA efficiently even in the absence of reducing agents. The main reactive oxygen species responsible for the DNA strand cleavage have been determined using radical scavengers. A probably mechanism of the DNA damage is proposed.
Study of Sb‐doped SnO2 Gray Ceramic Pigment with Cassiterite Structure
Authors: Tena M. A. , Sorlí S. , Llusar M. , Badenes J. A. , Forés A. , Monrós G. 
Published: August 2005

AbstractIn this study, SbxSn1−xO2 (0 ≤ x ≤ 0.5) compositions were synthesized by the ceramic method from Sb2O3‐SnO2 and Sb2O5‐SnO2 mixtures and characterized by Differential thermal analysis (DTA) and thermogravimetric analysis (TG), X‐ray diffraction, UV‐V‐NIR spectroscopy and CIE L*a*b* (Commission Internationale de l'Eclairage L*a*b*) parameters measurements. Solid solutions with cassiterite structure were obtained at 1300 °C. These solid solutions are stable into glazes. From Sb2O3, light gray coloured materials were obtained. From Sb2O5, bluish gray coloured materials were obtained at 1300 °C/6h when x ≥ 0.3. SbxSn1−xO2 with 0.3 ≤ x < 0.5, T = 1300 °C and Sb2O5 might be established as compositional range, fired temperature and antimony precursor to obtain gray ceramic pigments in this system.
Novel Cyclometallated Complexes Derived From a Halogenated Thiosemicarbazone. Crystal and Molecular Structures of 2‐FC6H4C(Me)=NN(H)C(=S)NHPh and[(Pd{2‐FC6H3C(Me)=NN=C(S)NHPh})2(μ‐PPh2(CH2)2PPh2)]
Authors: Adrio Luis A. , Amoedo Adriana , Antelo José M. , Fernández Jesús J. , Martínez Javier , Ortigueira Juan M. , Pereira M. Teresa , Vila José M. 
Published: August 2005

AbstractTreatment of the thiosemicarbazone 2‐FC6H4C(Me)=NN(H)C(=S)NHPh, a, with palladium(II) acetate in acetic acid, or with lithium tetrachloropalladate(II) in methanol, gave the tetranuclear cyclometallated complex [Pd{2‐FC6H3C(Me)=NN=C(S)NHPh}]4 (1a). Reaction of 1a with the diphosphines Ph2P(CH2)2PPh2 (dppe), Ph2PCH=CHPPh2 (trans‐dpe) Ph2P(CH2)3Ph2 (dppp) or Ph2P(CH2)4Ph2 (dppb) in a 1:2 molar ratio gave the dinuclear cyclometallated complexes [(Pd{2‐FC6H3C(Me)=NN=C(S)NHPh})2(μ‐Ph2P(CH2)nPPh2)], (n = 2, 2a; 3, 4a; 4, 5a) and [(Pd{2‐FC6H3C(Me)=NN=C(S)NHPh})2(μ‐Ph2PCH=CHPPh2)], (3a). The X‐ray crystal structure of ligand a and of complex 2a are described. The structure of complex 2a shows the palladium atom is bonded to four different donor atoms: C, N, S and P.