bluuebunny/crossref_metadata_2025_split huggingface dataset:
Tension Headaches: Muscle Overactivity or Psychogenic Pain
Authors: Haber Joel D. , Kuczmierczyk Andrzej R. , Adams Henry E. 
Published: June 2005

SYNOPSISIn two exploratory studies it was attempted to develop psychophysiological and self‐report criteria for differentiating MCH and psychogenic headache. Subjects diagnosed as having muscle contraction headaches were assigned to low and high EMG groups following measurement of the frontalis muscle in a headache state. It was hypothesized that the low EMG group would display characteristics of psychogenic pain disorders. In the first study, nine subjects with high EMG, nine subjects with low EMG and nine control subjects participated. The results show that basal levels in a non‐headache and headache state for the high EMG group were significantly different than the low EMG group, which were similar to control subjects. The low EMG group's self‐report data were consistent with the hypothesis of a psychogenic disorder. The second study determined if changes in EMG activity across headache and pain‐free states was a reliable effect by assessing frontalis EMG in three independent groups in two headache and two non‐headache states. The results showed systematic changes in EMG in headache and non‐headache states only for the high EMG group. These results suggest that accurate classification of headache disorders may alleviate some of the contradictory data in the headache literature.
Atypical Facial Pain: A Reappraisal
Authors: Reik Louis 
Published: June 2005

SYNOPSISAtypical facial pain is a syndrome of chronic facial pain affecting mainly young women who are often emotionally disturbed. Current opinion favors a psychogenic cause for it, but no causal relationship has been established: not all those affected are emotionally disturbed and no single psychiatric disorder predominates among those who are. Early reports of the syndrome in fact described a migraine‐like disorder in which either episodic facial pain or episodic exacerbations of chronic pain were associated with arterial tenderness, a variety of autonomic symptoms and signs and sometimes a response to treatment with vasoconstrictors. Painful dilation of craniofacial arteries may cause atypical facial pain.
Endorphin Levels in Headache Syndromes
Authors: Fettes Ivy , Gawel Marek , Kuzniak Sandy , Edmeads John 
Published: June 2005

SYNOPSISPlasma levels of immunoreactive b‐endorphin were found to be lower in patients with classical migraine than in patients with common migraine or chronic daily vascular headache or the control group. A role for b‐endorphin in the mechanism of the neurological dysfunction in classical migraine is suggested.
Extracranial Vascular Responses to Sublingual Nitroglycerin and Oxygen Inhalation in Cluster Headache Patients
Authors: Drummond P.D. , Anthony M. 
Published: June 2005

SYNOPSISPhotoplethysmography was used to record pulsations from the superficial temporal artery and supraorbital region in 23 patients suffering from cluster headaches, in 10 patients between bouts of headache, and in 10 control subjects. Pulsations were measured before and after the administration of 0.9 mg nitroglycerin sublingually, at the onset and height of cluster attacks and after inhalation of 100% oxygen for 10 minutes. Following nitroglycerin administration, increases in superficial temporal artery pulsations were greater on the symptomatic than on the nonsymptomatic side in patients who later developed headache. This persisted during cluster headache. By contrast, the increase in superficial temporal artery pulsations was greater on the nonsymptomatic side in patients who did not develop headache. The cause of this paradoxical response is unclear. Inhalation of oxygen produced significantly greater reduction of supraorbital pulsations on the symptomatic side in patients with headache. Decreases in both arterial territories following oxygen inhalation were significantly greater during cluster headache than between bouts or than in control subjects.
The Influence of Pain State on Physiological Reactivity of Tension Headache Sufferers
Authors: Hursey Karl G. , Holroyd Kenneth A. , Penzien Donald B. , Holm Jeffrey E. 
Published: June 2005

SYNOPSISThis study compared physiological reactivity to stress of subjects who frequently experience tension headaches and subjects who rarely get headaches. Physiological measures were Frontal and Trapezius muscle tension and Heart Rate. Subjects prone to headaches and subjects not prone to headaches did not differ on any variable, although there was a trend for subjects who were prone to headaches to have the highest Frontal muscle tension levels. For further analyses, subjects prone to headaches were separated into two groups: Subjects with headache during the psychophysiological assessment and subjects who were headache‐free during the assessment. Only subjects who were prone to tension headaches and who were actually experiencing a headache at the assessment had significantly higher Frontal muscle tension than controls who were not prone to headaches. These results suggest greater attention needs to be paid to the subjects' current headache state in research on the psychophysiology of headache.
Epidemiology of Headache in Elderly Correlations With Life Conditions and Socio‐professional Environment
Authors: Serratrice G. , Serbanesco F. , Sambuc R. 
Published: June 2005

SYNOPSISThe decreased frequency of headache in the aged is generally acknowledged. Thus in a general population, Waters (1975) reported 74% men and 92% women suffering from headaches and ranging between 21 and 34 years, while in a group aged 75 years or more, he reported only 21% men and 55% women. Likewise Newland et al (1978) mentioned 88% men and 96.7% women ranging between 21 and 34 years suffering from headaches and only 45.5% men and 52.7% women aged 75 years or more. Our previous study18 dealed with a group of 1990 headache sufferers (H.S.), who consulted for isolated headache among whom we noticed a low percentage (about 5%) of individuals over 65.This decrease of headaches in aged people is difficult to explain and there are few studies concerning headaches in the elderly. Prospective studies were carried out in poorly homogeneous groups examined by written questionnaires,3,4,5,6. less accurate than a direct examination. Conversely, this present study deals with a group of hospitalized patients, more homogeneous as regards the age, examined and followed up very closely. There are still no studies tending to compare H.S. and non‐headache sufferers (N.H.) and dealing with the difference or relationship between them. The aim of this work is an epidemiological and clinical analysis within a group of old people and then a comparison between this group and another of N.S. to determine if the life conditions and the socio‐professional environment have any influence on the occurrence of headaches.
Corneal Sensitivity in Cluster Headache
Authors: Vijayan N. , Watson Craig 
Published: June 2005

SYNOPSISCluster headache pain is thought to arise from vasodilatation, but a neural origin of the pain has never been completely excluded. Some patients with cluster headache have complained of subjective diminution of sensation over the ipsilateral forehead. This is hard to quantitate and is often variable. Besides, ablation of trigeminal sensory pathways has been re sorted to for relief of pain in some intractable cases.The present study was undertaken to quantitatively assess the sensitivity of the cornea in cluster patients. Fifteen cluster headache patients were the subjects of this study. Measurement of the corneal sensitivity was undertaken using a Cochet‐Bonnet Aesthesiometer. There was no difference between the affected and the unaffected eye. There was no difference in the sensitivity when testing was done during the cluster period and later on when the patients were in remission. It is concluded from this study that there is no objective evidence for involvement of trigeminal sensory pathways in patients with cluster headache.
Medical Diagnoses and Problems in Individuals With Recurrent Idiopathic Headaches
Authors: Featherstone Harvey J. 
Published: June 2005

SYNOPSISTwo hundred cases with recurrent idiopathic headache and 200 age‐ and sex‐matched controls without headaches were compared for the occurrence of medical problems and diagnoses according to their primary physicians. Hypertension, vertigo and dizziness, peptic ulcer, gastroesophageal reflux and depression and/or anxiety were among diagnoses seen more frequently in the headache cases, while nephrolithiasis, excessive ethanol use and abdominal pain in women were more common in the controls. There were no significant differences between the two groups in the diagnosis of cardiac disease, including mitral valve prolapse and ischemic heart disease, and occlusive cerebrovascular disease. Possible underlying mechanisms are discussed. These findings need confirmation and further investigation.
The Prevalence of Headache in a Small New Zealand Town
Authors: Paulin Judith M. , Waal‐Manning Hendrika J. , Simpson F. Olaf , Knight Robert G. 
Published: June 2005

SYNOPSISInformation on the prevalence, characteristic features and possible causative factors of headache was collected from 1138 adults who participated in a multiphasic health survey in Milton in May 1981.Thirty‐nine percent of men and 60% of women experienced headaches in the year preceding the survey. Total prevalence of headache peaked in men 30–39 years and in women aged 20–29 years and thereafter decreased with increasing age.The most commonly reported positions for headache were at the forehead unilaterally and bilaterally. The most common precipitating factors were ‘too much’ alcohol (men only), tiredness, mental stress and eye strain. Chocolate was the food most commonly blamed for the headache.No association was found between headache frequency and blood pressure or smoking habit. However the psychometric scores for anger, anxiety and depression were positively related to frequency of headache.
An Approach to the Nature of Tension Headache
Authors: Chun Wang Xing 
Published: June 2005

SYNOPSISClinical, EMG and therapeutic studies were used to explore the nature of tension headache. The EMG data indicated that muscle contraction was not important in the genesis of these headaches. In our 402 patients, tiredness, sleepiness, and hypomnesia were very common and, with the headaches, were improved following administration of the CNS stimulant caffeine sodium benzoate. It is suggested that inhibitory mechanisms in the CNS may be important in producing tension headaches.
Migraine and Muscle Contraction Headaches: a Continuum
Authors: Featherstone Harvey J. 
Published: June 2005

SYNOPSISThere is increasing evidence that migraine and muscle contraction headaches are similar; rather than being different entities, they may vary in symptom quantities instead of having qualitative differences. Analysis of elements of the headache history in 50 consecutive idiopathic headache patients failed to show evidence for distinct headache types. Quantitation of symptoms and characteristics showed a unipolar distribution; reported pain severity was directly related to the symptom quantitation score. These two statements were true for three different history scoring systems, from the simplest (quantitation of nausea, unilaterality and aura) to the most detailed (quantitation of nausea, unilaterality, aura, photophobia, throbbing pain, headache location, family history and clustering). Headache scores were lower for patients previously diagnosed as “tension” headache patients compared to those diagnosed previously as having “migraine”. Joint occurrence of the major migraine symptoms of nausea, aura and unilaterality was by chance. These data support the headache severity model described by others, and do not support the existence of separate, distinct idiopathic headache entities.
Migraine ‐ Cluster Headache Syndrome
Authors: Solomon Seymour , Karfunkel Perry , Guglielmo Karen M. 
Published: June 2005

SYNOPSISThe migraine‐cluster headache syndrome is defined as headaches that are predominately of one type but with at least one major timing factor plus three lesser features of the other or five lesser features of the other (no more than one of the opposing features is a weak differential feature). The most important factors distinguishing migraine (M) from cluster headache (CH) are the timing of attacks (random occurrence versus clustering, frequency, duration, hour of onset) and the prodromal phenomena which occur with classical M, but are rarely seen with CH. Somewhat less significant differentiating characteristics are the associated symptoms of ipsilateral eye redness and tearing, nasal congestion and secretion, and partial Horner's syndrome which often accompany CH, in contrast to the symptoms of nausea and vomiting commonly associated with M. Also helpful in establishing the diagnosis are the quality, site and recurrent laterality of the pain, as well as its aggravating and ameliorating factors. Weak features in the differential diagnosis of M and CH are age of onset, sex, family history, and response to therapy.Patients with M or CH seen at the Headache Unit of Montefiore Medical Center during the past two years were evaluated for the occurrence of the migraine‐cluster headache syndrome. Nine (1.0%) of 923 patients with M had 4 or more features of CH and 5 (3.2%) of 154 patients with CH had 4 or 5 characteristics of M. In 4 patients symptoms of M and CH were blended in such a way neither headache predominated.
Complicated Migraine and Cerebral Angiography: a Report of an Unusual Adverse Reaction
Authors: Kwentus Joseph , Kattah Jorge , Koppicar Mohesh , Potolicchio Samuel J. 
Published: June 2005

SYNOPSISAdverse reactions have been previously reported when cerebral angiography is performed on patients with complicated migraine. We report a case of complicated migraine in which cerebral angiography produced come and prolonged suppression of EEG rhythms. Possible mechanisms are discussed.
Plasma Methionine Enkephalin Levels — A Biological Marker for Migraine?
Authors: Mosnaim Aron D. , Wolf Marion E. , Chevesich Jorge , Callaghan Owen H. , Diamond Seymour 
Published: June 2005

SYNOPSISMigraine patients, either during an attack or when pain‐free, have significantly higher platelet‐rich and platelet‐poor plasma methionine‐enkephalin levels than healthy race‐ and sex‐matched and age‐comparable controls. Although we did not observe differences in the platelet‐rich samples between the patients subgroups, platelet‐poor samples had higher peptide levels during a pain‐free period than the values obtained for the patients during a migraine episode. Similarly, platelet‐rich samples obtained from controls and patients during an attack had higher methionine‐enkephalin levels than their corresponding platelet‐poor plasma samples. These results provide new evidence supporting the involvement of the endogenous peptides in the etiology of migraine headache and suggest that plasma methionine‐enkephalin levels could serve as a biological marker for this condition.
Migraine and Cluster Headache Treatment With Calcium Antagonists Supports a Vascular Pathogenesis
Authors: Meyer John Stirling , Nance Matthew , Walker Mary , Zetusky Walter J. , Dowell Richard E. 
Published: June 2005

SYNOPSISClinical research during the past four years in this and other laboratories has demonstrated therapeutic effectiveness of three different calcium channel blockers in the prophylaxis of migraine and cluster headaches. The drugs are nimodipine, nifedipine and verapamil. Clinical observations and cephalic hemodynamic responses correlated before and during treatment with nimodipine show extremely low incidences for development of tolerance and/or side effects plus normal glucose tolerance and calcium dependent insulin secretion before and during nimodipine therapy. The results confirm potent and highly selective calcium entry blockade of cephalic smooth muscle receptors by nimodipine. Nifedipine and verapamil showed less therapeutic effectiveness in controlling headaches, higher incidence for development of tolerance and side‐effects with less consistent cephalic hemodynamic changes. Taken together these observations during treatment of migraine and cluster with calcium antagonist support Wolff's theory of vascular head pain.
Comparative Efficacy of Calcium Antagonist Drugs in the Prophylaxis of Migraine
Authors: Solomon Glen D. 
Published: June 2005

SYNOPSISSince 1981, numerous studies have shown the efficacy of calcium antagonist drugs in the prophylaxis of migraine. Five different agents: flunarizine, nimodipine, verapamil, nifedipine, and diltiazem, have been evaluated. This paper reviews these studies with regard to reduction in migraine frequency, percentage of patients showing improvement, percentage of patients showing 50% or greater improvement, and adverse reactions.These studies show that these five calcium channel blockers are effective in migraine prophylaxis. Comparison of data suggest no major differences between the five agents reviewed with regard to efficacy. Furthermore, adverse reactions were divided between vascular and gastrointestinal with the “systemically active” drugs, and behavioral and muscular with the “cerebro‐specific” drugs. Lastly, most trials show a therapeutic delay of 3 to 8 weeks with the calcium channel blockers.
Ranitidine Headache
Authors: Epstein Charles M. , Klopper Jeffrey 
Published: June 2005

SYNOPSISFive patients developed severe headaches in close association with the use of ranitidine. Two required hospitalization and three had recurrence of headaches on rechallenge. One had exacerbation of classic migraine. Headaches varied from intermittent and throbbing to steady and continuous, and onset was 12 hours to several months after beginning treatment; but all patients improved dramatically within 48 hours after ranitidine was discontinued. The great variability of ranitidine headache has important clinical and theoretical implications.
Prolactin and Migraine: Effect of L‐Dopa on Plasma Prolactin Levels in Migraineurs and Normals
Authors: Nattero G. , Corno M. , Savi L. , Isaia G.C. , Priolo C. , Mussetta M. 
Published: June 2005

SYNOPSISSince in migraineurs a change in dopaminergic tone has been hypothesized and since in man prolactin secretionby the lactotroph cells is controlled by hypothalamic inhibitory factors (of which dopamine is the best known), wedecided to investigate plasma prolactin (PRL) response to L‐Dopa in a group of migraineurs.We tested 5 women suffering from common migraine and 5 healthy women as controls.A different behaviour of PRL secretion was observed in the two groups. In migraineurs the inhibition of PRLsecretion was less marked than in normals, with a statistically significant difference at 30 and 60 minutes.This difference might suggest a reduced responsiveness of the pituitary lactotroph cells to the action ofdopaminergic agents. The mechanisms accounting for this peculiar behaviour of PRL secretion in migraineurs arestill to be elucidated.
Transient Focal Headaches with Persistent Ipsilateral EEG Disturbances
Authors: Goldenberg E. , Arlazoroff A. , Tauber T. , Varsano D. 
Published: June 2005

SYNOPSISTwo children with severe transient focal headaches are presented. Complete relief was obtained aftercyproheptadine treatment. A characteristic feature of these cases was focal persistent irritative EEGdisturbances. All the other diagnostic examinations were normal. The possibilities of migraine alone, or ofheadache as an equivalent of epileptic fit, are discussed separately with a review of the relevant literature.Finally, the probability of an underlying autonomic epileptic phenomenon causing a classic migraineattack is raised.
Hereditary Dysrhythmic Headache
Authors: Shimomura Tokio , Nishikawa Seihou , Takahashi Kazuro 
Published: June 2005

SYNOPSISFifteen families including 35 patients with chronic headache showing electroencephalographic (EEG)abnormalities and dysautonomia are reported on. Nine families including 18 patients with chronicheadache, without EEG abnormalities, served as controls. In the patients with EEG abnormalities, sixpatients (17.1%) suffered from common migraine, 28 (80.0%) from muscle contraction headache and one(2.9%) from combined headache. All the patients had 6‐7Hz EEG abnormalities such as 6‐7Hz slow waves,6‐7HZ spike & wave complexes and 6‐7Hz positive spikes. Most of the patients (77.1%) manifesteddysautonomic symptoms. These symptoms were observed in only 16.7 per cent of the patients with afamily history of headache, without EEG abnormalities. In chronic headache patients, it is suggested thatthere is a group with hereditary dysrhythmic headache characterized by dysautonomia.
Psychopathology in Volunteers for Headache Research: Initial versus Later Respondents
Authors: McAnulty David P , Rappaport Neil B. , Waggoner Craig D. , Brantley Phillip J. , Barkemeyer Charles , McKenzie Sandra J. 
Published: June 2005

SYNOPSISThe present study examined psychopathology in 64 volunteers for an on‐going headache research project.Subjects (19 to 58 years old) who responded immediately to newspaper articles requesting volunteersdiffered in levels of psychopathology from those who responded later. It was further noted that thedifferences observed occurred on those MMPI scales found to discriminate among headache diagnosticgroups (Scales 2, 7, and 8). Recommendations for future research are made in light of these findings.
Migraine Warnings
Authors: Amery Willem K. , Waelkens Jan , Vandenbergh Vic 
Published: June 2005

SYNOPSISThe early prodromal phase of a migraine attack, poorly documented yet conceivably relevant to the pathogenesisof the attack, was studied in 149 patients, mainly female, with classic or common migraine who were aware ofthese prodromal phenomena. On a questionnaire a variety of prodromes, nearly all well reproduceable, werereported. Day‐before and day‐of‐attack symptoms were noticed by 79% and 88% of the patients, respectively. Inthe other 12–21% signs were mainly observed by the partner. Some prodromes invoked the “cause orconsequence?” question as to certain trigger factors. Others bore rather striking similarities to the classic aura, sothat evolutive symptoms seemed to merge with the early part of the migraine attack. The incidence, or at least theawareness of prodromes was correlated with the occurrence of some factors aggravating the headache and withpost‐attack symptoms, was higher in women, in patients with long‐standing disease and frequent attacks, inpatients who had other types of headaches as well, and in classic migraine sufferers.
Emergency Treatment of Intractable Migraine
Authors: Gallagher R. Michael 
Published: June 2005

SYNOPSISThe treatment of refractory or prolonged migraine is a difficult problem for the physician and patient. Treatment varieswith physician and location, but widely accepted is therapy with an injectable analgesic in combination with asedative/antimetic and/or ergotamine.Since prolonged migraine headache is said to be associated with cranial vascular inflammation, the addition ofcorticosteroids to treatment may enhance relief. An analysis was conducted of 162 patients who were treated with andwithout steroids for intractable migraine headache in the emergency department of a large community hospital.Patients were divided into three groups. Group I consisted of 73 patients treated with meperidine and promethazine;Group II, 32 patients treated with dihydroergotamine and meperidine; Group III, 57 patients treated with meperidine,promethazine and dexamethasone. All patients were telephoned 24 hours after treatment to determine the degree ofheadache relief. Twenty‐one patients (29%) from Group I; 12 patients (37%) from Group II; and 41 patients (72%) fromGroup III reported marked relief.From this limited study, it appears that the inclusion of dexamethasone in the treatment of intractable migraineheadache is of benefit.