bluuebunny/crossref_metadata_2025_split huggingface dataset:
Produced Water WSOs Reduction by Topside Facilities Rearrangement
Authors: Neto S. Simoes , Germiniani J. C. , Lorenzo H. R. Di 
Published: October 2023

Abstract
This paper presents the results obtained in Water Soluble Organics (WSO) content in Produced Water (PW) after changing the process arrangement in one FPSO operated in Santos Basin, offshore Brazil.
The WSO content in oil and grease analysis has been discussed extensively in Brazil since the implementation of Standard Methods (SM) 5520B as the official standard for PW discharge to comply with environmental legislation. Historically, dispersed phase was the major component on water treatment. Therefore, most of offshore water treatment design focuses on physical separation.
Since SM 5520B replaced SM 5520F by the environmental agency, WSO started to share (with dispersed oil) an important variable on the O&W separation.
Most of Santos Basin units present high CO2 content on the production streams. Due to the gas and water equilibrium, it is expected produced water has an acid pH. The pH level impacts the WSO content during the separation steps. Based on our company experience, in pH values around 5 the polar compounds tend to stay in the oil dispersed phase.
Based on an offshore unit arrangement, depending on which separation step the water is collected, the pH can be as low as 5 or higher than 7. The pH calculations showed that to achieve the lowest pH, it is necessary to remove the most of water on the first three-phase separator. The first separator has the highest pressure (20 barg) and high CO2 content which leads to lower pHs due to water – CO2 equilibrium.
Based on the pH calculations, the new alignment was implemented. The impact on Oil and Grease (O&G) measurements were immediately observed. The analysis made on infrared analyzer reduced results up to 71%. Another positive side effect was the possibility to avoid oil production losses by 15 kbpd.
The conclusion is that for units with some amount of CO2, it is possible to reduce the WSO only by changing the process arrangement.
An update on high temperature tantalum capacitor technology
Authors: West D. , Demcko R. , Messina R. , Stanziola A. 
Published: October 2023

Developments and improvements in the materials, design and manufacturing of tantalum bulk capacitors have resulted in new case sizes, improved ESR, higher operating voltages and temperatures. This work discusses the basic design and manufacture of hermetic tantalum and wet tantalum capacitors and the resulting high temperature performance offered by each technology. Specifically, hermetic sealed tantalum capacitors offer a novel set of design options for the high temperature designer. This technology, exhibits superior stability when exposed to high temperatures, high humidity, and ambient atmosphere. The device is impervious to the typical capacitance drop common to high temperature capacitor operation. Thus they enable potentially significant size reductions, lower component counts, and reliability improvements in extremely high temperature applications, such as downhole oil drilling. Both electrical and physical comparisons are made between the characteristics of bulk stacked ceramic capacitors, hermetic tantalum and wet tantalum devices across an operating range of -55°C to +230°C. Lifespan and recommended de-ratings are presented.
Profile and Outcome of Prospective Non-Septic Lateral Sinus Thrombosis Patients from a Stroke Unit of a Developing Country
Authors: Mirza Abbas M. , Kulkarni Girish B. , Ramakrishnan Subasree , Mustare Veerendrakumar , Yadav Ravi , Gupta Arun K. 
Published: October 2023

Background:
Due to effective treatment of middle ear infections there is a change in etiologies causing lateral sinus thrombosis (LST) and outcome. There is a paucity of literature describing homogenous group of patients with nonseptic LST (NS-LST).

Objective:
To describe the clinical profile, risk factors, outcome of patients of NS-LST seen at a single center from South India.

Methods and Materials:
Prospective, observational study of 100 patients of NS-LST patients, diagnosed by magnetic resonance imaging (MRI) seen at the stroke unit.

Results:
During 2 years, 100 patients of NS-LST (isolated: combined: 27:73) (male: female: 44:56), mean age: 31.45 ± 11.13 years, were seen. Subacute presentation (74%) with headache, seizures, focal deficits, and features of raised intracranial pressure were presenting features. Hyperhomocysteinemia (61%), anemia (57%), postpartum state (41%), OCP use (37%), and low VitB12 (32%) were commonly seen risk factors. Imaging with MRI compared withcomputerized tomography (CT) had better diagnostic sensitivity (100% vs. 67%), detection of parenchymal (81% vs. 67%)/hemorrhagic (79% vs. 74%) lesions, and cortical vein thrombosis (31% vs. 15.46%). Treatment with anticoagulation and supportive therapy resulted in good outcome (mRS (0-2)) at 3 months in 81%. There were four deaths, all during admission (one – isolated, three – combined) and 11 patients underwent decompressive surgery. Patients with low GCS level of sensoriumat admission, hemiparesis, combined LST, cerebellar involvement, and decompressive craniectomy had a poor outcome.

Conclusion:
This single-center large cohort study of NS-LST patients brings out the clinical features, risk factors (peculiar to developing countries), and the superiority of MRI in the diagnosis. Majority of patients have good outcome, with low mortality with 10% requiring decompressive surgery.
A Novel Neuroimaging Phenotype in the X-Linked Intellectual Disability with a Missense Mutation of CNKSR2 Gene
Authors: Hosur Bharat , Sinha Rahul , Jain Narendra K , Muthanna Boverianda Aiyanna , Bansal Vandana , Singh Sonali , Kamila Gautam 
Published: October 2023

Background:
Mental retardation, X-linked, syndromic, Houge type (MRXSHG) is a form of mental retardation characterized by intellectual disability, speech and language impairments, and early-onset seizures. It has been recently recorded in Online Mendelian Inheritance in Man (OMIM), and only 10 cases have been reported in the literature so far.

Objective:
To highlight the novel neuroimaging findings in the pediatric X-linked intellectual disability with a missense mutation of connector enhancer of kinase suppressor of RAS2 (CNKSR2) gene.

Material and Methods:
We present a case of intellectual disability, refractory epilepsy, speech and language delay with subtle dysmorphism, and behavioral issues in an 11-year-old boy with novel neuroimaging findings in a CNKSR2 gene with missense mutation.

Results:
Brain MRI revealed involvement of the basal ganglia, predominantly the neostriatum, and along with the subependymal aspects with focal cavitations involving, especially the bilateral caudate heads. There was relative sparing of the globus pallidi and posterior putamina bilaterally. Whole-exome sequencing identified a hemizygous missense pathogenic variant in the CNKSR2 gene. The mother was found to be an asymptomatic carrier.

Conclusion:
This case report highlights the rare missense mutation in the CNKSR2 gene and abnormal neuroimaging findings, which further provide information about the phenotypic characteristics of X-linked syndromic intellectual disability.
Effects of laser irradiation and tooth mousse on tooth hypersensitivity after office bleaching: A non-randomized clinical trial
Authors: Sadri Mohammadmahdi , Nakhostin Afrooz , Salamat Fahimeh 
Published: October 2023

Background:
This study aimed to assess the effect of laser irradiation and Tooth Mousse on tooth hypersensitivity (TH) after office bleaching (OB).

Materials and Methods:
This clinical trial, parallel-design split-mouth nonrandomized was conducted on 30 patients requiring OB. After scaling and fabrication of a custom tray, 35% hydrogen peroxide was applied on all teeth, and 940 nm diode laser (10 W, Class IV, 110–240 V) was irradiated to the upper and lower right quadrants. Laser in off mode was used for the left quadrants. Bleaching agent was then reapplied. After completion of bleaching, a custom tray containing tooth Mousse was placed on the maxillary arch while the tray was used without the paste for the mandibular arch. A visual analog scale was used to assess the degree of TH at 15 min and 24 h after OB. Data were compared using t-test, paired t-test, and analysis of variance. Significance level was set at α = 0.05.

Results:
Comparison of TH at 15 min and 24 h after OB showed a significantly lower TH score in the left upper quadrant (tooth Mousse alone) than right upper quadrant (both laser and Tooth Mousse) (P < 0.05). The TH score in the right upper quadrant was significantly lower than that in the right lower quadrant (laser only) (P < 0.05). The mean TH score in the left upper quadrant was insignificantly lower than that in the left lower quadrant (no intervention) (P > 0.05).

Conclusion:
The use of 940 nm diode laser for OB increases the postoperative TH. The application of Tooth Mousse can effectively decrease TH after OB with/without laser irradiation.
Attitude of dental students toward evidence-based dentistry in Iran: A systematic review
Authors: Asgari Imaneh , Farahmand Hanieh , Ahmady Ali , Zahed Maryam 
Published: October 2023

Background:
Dentistry practice has become more complex and challenging in the recent years. The clinical decision-making process has experienced many problems due to changing socioeconomic patterns, knowledgeable patients, rapid technological advances, and information explosion. The present study reviewed the status of the attitude toward evidence-based dentistry (EBD) among dental students of Iran Universities. The effect of the educational intervention was also assessed.

Materials and Methods:
This systematic review was conducted according to the Preferred Reporting Items for Systematic review and Meta-Analysis checklist. Search strategy was developed by Medical Subject Headings terms and keywords surfing electronic available databases including Medline/PubMed and Google Scholar and local databases such as Scientific Information Database (SID) and Magiran. Two reviewers read the abstracts of all eligible papers and excluded the duplicates. They extracted the information of the full-text of the studies included in the review and assessed the quality by Joanna Briggs Institute critical appraisal checklist.

Results:
Ten studies including 8 cross-sectional and 2 interventional studies met the criteria. The assessment of the attitude of 937 dental students from a different region of the country toward EBD showed moderate to acceptable status using 3 different tools. In regard to educational interventions, 2 studies were successful to improve their attitude.

Conclusion:
Although the researchers presented good scores on the attitude questionnaires, the quality of the study tools, the eligible criteria for recruiting the participants and the method of evaluating the construct of attitude should be investigated in future studies.
Methanolic pomegranate dried peel extract improves cryopreserved semen quality and antioxidant capacity of rams
Authors: Aboelmaaty Amal M. , Kotp Mohamed S. , Fadl Aya M. , Abdelnaby Elshymaa A. , El-Seadawy Islam E. , El-Sherbiny Hossam R. 
Published: October 2023

Objective:
To select the appropriate concentrations of methanolic pomegranate extract supplemented in rams' semen extender for obtaining the best-cryopreserved semen quality.

Methods:
Tris-based semen extender was supplemented with 0.0, 0.40, 0.48, and 0.56 mg/mL pomegranate peel methanolic extract to extend semen collected from five native rams twice weekly for two months (n=80). Pooled (n=16) post-thaw semen characteristics were determined. Thawed seminal plasma of all supplemented and control groups were used to measure malondialdehyde (MDA), nitric oxide (NO), glutathione peroxidase (GPx), superoxide dismutase (SOD), ascorbic acid, zinc, copper, total cholesterol, low-density lipoproteins (LDL), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP).

Results:
The supplementation of Tris-based semen extender with 0.48 mg/mL semen extender resulted in the highest post-thaw sperm total motility (P<0.001), sperm progressive motility (P<0.001), live sperm (P<0.001), sperm plasma membrane integrity (P<0.001), acrosome integrity (P<0.001), SOD (P<0.05), zinc (P<0.001), total cholesterol (P<0.001), and LDL (P<0.001) with the lowest percentage of abnormal sperm morphology (P<0.001), the lowest lipid peroxidation (MDA, P<0.01), ascorbic acid (P>0.05), and LDH (P>0.05).

Conclusions:
Pomegranate peel methanolic extract 0.48 mg/mL supplemented to Tris-based semen extender of rams is the best enrichment in preserving the sperm post-thaw characteristics via improving biochemical profiles and antioxidant capacity.
The diagnostic accuracy of perfusion-only scan in the diagnosis of pulmonary embolism in the era of COVID-19: A single-center study of 434 patients
Authors: Cengiz Turgut Bora , Abdelrahman Ahmed , Rohren Scott A. , Doucette John , Ghesani Munir 
Published: October 2023

Abstract:

INTRODUCTION:
There is a paucity of data in the literature regarding the diagnostic accuracy of perfusion (Q)-only studies in the absence of ventilation images. This study aims to assess the diagnostic accuracy of Q-only imaging in the pandemic era.

METHODS:
Patients who underwent Q-only imaging for pulmonary embolism between March 2020 and February 2021 were analyzed. Patients who underwent lung quantification analysis were excluded. Q-only test results were reported as per modified PIOPED II criteria and single positron emission tomography/computed tomography (SPECT/CT) imaging was performed as needed. Patients were considered concordant or discordant by correlating the Q-only results with CT angiogram (CTA) or clinical diagnosis made through chart review. The diagnostic accuracy was calculated after excluding intermediate probability and nondiagnostic studies.

RESULTS:
Four hundred and thirty-four patients were identified. One hundred and twenty-eight patients (29.4%) underwent ultrasound Doppler, 37 patients (8.5%) underwent CTA, and 16 patients (3.6%) underwent both. After excluding patients with intermediate probability or nondiagnostic studies and who did not have follow-up (a total of 87 patients [20%]), 347 patients were enrolled in the final analysis. The combined planar and SPECT/CT sensitivity and specificity were 85.4% (72.2%–93.9% confidence interval [CI]) and 98.7% (96.9%–98.6% CI), respectively. The positive predictive value (PPV) of the Q-only imaging was 89.1% (77.3%–95.1% CI) and the negative predictive value (NPV) was 98.2% (96.4%–99% CI). The sensitivity with SPECT/CT reached 100% (CI: 71.5%–100%) with a specificity of 92.3% (CI: 64%–99.8%). The PPV was 85.7% (CI: 62.1%–95.6%) and the NPV was 100%.

CONCLUSION:
Q-only imaging provides clinically acceptable results. The sensitivity of the Q-only scan is increased when coupled with SPECT/CT.
Association of CYP11A1 Polymorphisms with Recurrent Pregnancy Loss in the Female Population of Punjab
Authors: Rayat Amanjot Kaur , Thapar Pallvi , Kaur Mandeep , Singh Sukhjashanpreet , Kaur Anupam 
Published: October 2023

Background:
Recurrent pregnancy loss (RPL) is defined as the failure of two or more clinically recognised pregnancies before 20 weeks of gestation. The prevalence of clinically evident RPL is 1%–2% worldwide. The aetiologies of RPL include uterine anatomic anomalies, uncontrolled diabetes mellitus, untreated hypothyroidism, parental chromosomal abnormalities, antiphospholipid antibody syndrome, thrombophilia, genetic abnormalities and infections.

Aims:
This study was aimed at investigating the possible association between CYP11A1 (rs11632698) and (rs4077582) polymorphisms with RPL in the female population of Punjab.

Settings and Design:
The case– control study was conducted on 170 subjects, of which 80 RPL cases and 90 controls were analysed.

Materials and Methods:
Genotypic analysis was performed using the polymerase chain reaction – restriction fragment length polymorphism. Statistical Analysis Used: Pearson’s Chi-square test was used.

Results:
The genotypic frequency of CYP11A1 (rs11632698) A > G polymorphism was statistically significantly different amongst cases and controls (P = 0.00001). It was observed that the presence of the G allele might increase the risk of RPL. A Chisquare analysis of CYP11A1 (rs4077582) (P = 0.01) indicated a significant difference amongst the genotypes of cases and controls of RPL.

Conclusion:

CYP11A1 variants (rs11632698 and rs4077582) may be useful markers in determining the genetic susceptibility to the pathogenesis of RPL. Keywords: CYP11A1, recurrent miscarriage, recurrent pregnancy loss, rs11632698, rs4077582, spontaneous abortion.
Association between Late Manifestations of Testicular Dysgenesis Syndrome and Anogenital Distance: A Systematic Review and Meta-analysis
Authors: Tsutida Carolina Arissa , Veiga Ana Carolina Bernard , Martino-Andrade Anderson Joel , Andrade Diancarlos Pereira de , Mello Rosiane Guetter , Müller Juliane Centeno 
Published: October 2023

Background:
In 2001, Skakkebæk et al. proposed that certain male reproductive disorders might be grouped into a syndrome called testicular dysgenesis syndrome (TDS), as they all appear to be associated with disruption of the embryonic and foetal programming of gonadal development. TDS may be manifested in early life by the presence of genital malformations (hypospadias and cryptorchidism) and in adult life as disorders represented by low sperm counts and testicular cancer. Changes in androgen hormones during the foetal development, in addition to resulting in TDS, can also cause permanent changes in anopenile anogenital distance (AGDap) and anoscrotal anogenital distance (AGDas).

Aims:
The objective of this study was to determine whether there is a relationship between late manifestations of TDS and reduced anogenital/anoscrotal distance.

Materials and Methods:
The present study is a systematic review and meta-analysis. The research included papers from 2001 to 2020, comprising a total of 737 articles, and 13 articles were selected.

Results:
Linear regression analysis was performed to evaluate the relationship between the two anogenital distance measures, which showed a significant positive association (P = 0.039). A meta-analysis was also performed and compared AGDap and AGDas between control and case groups, with cases defined as men with any late TDS manifestation. These data showed a significant reduction in AGDas in the affected population (P = 0.04), but no differences in the AGDap measure (P = 0.59).

Conclusion:
Our study confirmed a significant relationship between reduced AGDas and late manifestations of TDS, providing further support to the association between prenatal androgen deficiency and late-onset reproductive disorders.
ASSESSMENT OF COGNITIVE FUNCTIONS AMONG SUBJECTS WITH SUBCLINICAL HYPOTHYROIDISM
Authors: Nabi Tauseef , Rafiq Nadeema 
Published: October 2023

Abstract

Objective:
The consequences of overt hypothyroidism on CNS are well known. In contrast, there is less evidence regarding the effects of subclinical hypothyroidism (SCH) on cognitive functions. Studies have shown a variable association between SCH and cognitive dysfunction. This study was done to assess the prevalence of cognitive impairment among subjects with SCH.

Methods:
The participants were 100 subjects (aged 40-60 years) with SCH and similar number of age-matched euthyroid controls. Subclinical hypothyroidism was defined as serum TSH level > 4.5 mIU/L with normal FT3 and FT4. Participants were interviewed by a single observer. Cognitive function was assessed by mini mental state examination (MMSE) and clock drawing test (CDT). MMSE scores ≤24 is indicative of cognitive impairment. For CDT a score of ≥3 represents a cognitive deficit, while a score of 1 or 2 was considered normal.

Results:
The mean age of patient group was 47.4 years, and BMI of 26.1kg/m2 which were comparable to controls who had a mean age of 46.1 years (P=0.16) and mean BMI of 25.9 kg/m2 (P=0.25). All other baseline variables including sex ratio, co-morbidities, family history of dementia, smoking, alcohol use, education and exercise were also comparable in both groups. The mean TSH was 7.8 mIU/L in patients and 2.7 mIU/L in controls (P< 0.05).The mean MMSE score was 26.1 in patient group and 27.7 in controls (P=0.31) The patients had mean CDT of 2.32 and controls 2.44 (P=0.61). Cognitive impairment by MMSE (score ≤24) was found in 22.0% of patients and in 16.0% of controls (P=0.14), also the cognitive impairment by CDT (score of ≥3) was present in 27.0% of patients and 25.0% of controls (P=0.29).

Conclusion:
In the present study we have found that the prevalence of cognitive impairment in subjects with SCH is similar to the age matched controls. Therefore the potential benefit of levothyroxine therapy if used with an aim of improving cognitive functions becomes doubtful.
Liquid-Volume Measurement Estimation Skills of Gifted Students and Suggestions for Saving Water
Authors: Er Zubeyde 
Published: October 2023

Water is vital for the survival of living things. It is water that sustains all living organisms, all biological life, and all human activity. Water constitutes 3/4 of the world, 60% of the human body. The need for water is increasing day by day due to the rapid increase in the population and the fact that the water resources remain constant. It is important for individuals to be conscious about water consumption, to be aware of how much they consume. In this context, in this research, students’ estimates of the amount of water they consume, liquid-volume measurement estimates and their views on water conservation were examined. This study aims to examine the liquid-volume measurement estimation skills of gifted students and to examine their views on water conservation. This study was conducted as per the case study design, which is one of the qualitative research designs. The study group of the study consisted of 24 gifted students studying in the 6th grade in a Science and Art Center in a province located in the southern region of Turkey in the 2022-2023 academic year. As a result of the research, it was observed that the students had moderate liquid-volume estimation skills and the male students had more liquid-volume estimation skills than the female students. In addition, it was concluded that students had a low average score in liquid-volume estimation problems involving real-life situations, and that the most opinions about water conservation were in the theme of limitation and penalty application.
Inventarisasi Tumbuhan Asing Invasif di Kawasan Taman Hutan Raya Ir. H. Djuanda
Authors: Supriyatna Ateng Supriyatna , Aulia Annisa Ridha , Cahyanto Tri 
Published: October 2023

Invasive alien plant species are plant species that occupy and dominate an area so that they become one of the threats to damage ecosystems, habitats, flora and fauna. The purpose of the study was to determine the types of invasive alien plants found in the Ir. H. Djuanda Forest Park and to find out the potential use of invasive alien plant species for the community. The research design used exploratory method combined with line transect. The results showed that there were 50 species belonging to 27 families, especially in the Compositae (13 species), Poaceae (5 species), and Acanthaceae (4 species). Based on the species composition in each block, the species found in the Utilization Block (29 species) were more diverse than the Protection Block (27 species) and Collection Block (10 species). Based on the literature review, the invasive alien plant species found in the Ir. H. Djuanda Forest Park has the potential to be developed as a animal feed, medicinal plant, processed food, and ornamental plant. Keywords: Species composition, Potential, Invasive alien plants species