bluuebunny/crossref_metadata_2025_split huggingface dataset:
Health risk assessment for potentially toxic elements accumulation in Amaranthaceae family cultivars and their correlation with antioxidants and antinutrients
Authors: Sharma Pooja , Mahongnao Sophayo , Gupta Asmita , Nanda Sarita 
Published: February 2024

Abstract

Delhi's agricultural hub, nestled along the Yamuna floodplains, faces soil and water contamination issues. Utilizing organic waste composts is gaining traction to improve soil quality, but uncertainties remain about their efficacy in reducing harmful elements. The study examined three Amaranthaceaecultivars, comparing organic waste composts with chemical fertilizer. It calculated correlations between heavy metals, antioxidants, and antinutrients to assess their bioremediation potential. PTE levels in soil and leaves were measured by ICP-MS, while antioxidants and antinutrients were analyzed with UV-VIS spectroscopy. The study revealed higher PTE levels in floodplain soil, with Cr, Ni, and Cd exceeding safe limits in all soil cultivars. Compost amendments reduced these pollutants by 28% compared to chemical fertilizers, decreasing bioaccumulation by 20%. Health risk assessments showed lower risks in compost-amended cultivars. Additionally, compost-amendment displayed a stronger correlation between PTE and antioxidants, suggesting effective bioremediation. Overall, compost amendments offer promise for mitigating PTE in metropolitan floodplains.
Optimizing Short Video Recommendation: A Multimodal Fusion Approach Leveraging Graph Neural Networks
Authors: McDonough Don L. , Marlon Jennifer , Bond Jonathan 
Published: February 2024

Abstract
In the dynamic landscape of contemporary social media, short videos have emerged as a dominant form of content consumption, prompting intensified research focus on short video recommendation scenarios. Users engaged with short videos exhibit unique characteristics, marked by diverse and multi-level dynamic interests. Addressing the challenges inherent in short video recommendation systems, this paper introduces a hybrid recommendation algorithm model that capitalizes on multimodal information. The model incorporates user-side auxiliary information into its network structure, delving into the profound interests of users. It assesses the significance of each dimension within user and item feature representations during the scoring prediction task. Furthermore, the application of graph neural networks in the recommendation system is enhanced through the integration of an attention mechanism. This mechanism facilitates the fusion of multi-layer state output information, enabling more effective participation of shallow structural features provided by the intermediate layer in the prediction task. Through extensive experimentation on different datasets, the proposed model demonstrates improved recommendation accuracy compared to traditional recommendation algorithms, affirming the feasibility and effectiveness of the approach.
Automatic calibration of SWMM parameters based on multi-objective optimisation model
Authors: Wang Tao , Zhang Longlong , Zhai Jiaqi , Wang Lizhen , Zhao Yifei , Liu Kuan 
Published: February 2024

Abstract

To address the issue of low accuracy and inefficiency in the traditional parameter calibration methods for the SWMM model, this paper constructs an automatic parameter calibration model based on multi-objective optimisation algorithms. Firstly, the Sobol method and GLUE method are utilised to determine sensitive parameters and their ranges, aiming to narrow down the solution space and expedite the model-solving speed. Secondly, the NSGA-3 multi-objective optimisation algorithm based on the Pareto theory is applied for the optimisation and calibration of sensitive parameter sets. The model is validated in the rainwater drainage system with independent runoff in a residential area in a northwestern city in China. The results show that parameters such as N-Imperv and KSlope are highly sensitive to the model output under the land-use conditions of the study area. The simulation accuracy of the multi-objective continuous optimisation algorithm is significantly better than that of the single-objective genetic algorithm. The simulation results of the SWMM model under multi-objective optimisation demonstrate a certain level of reliability and stability. The research findings can provide technical support for the automatic calibration of SWMM model parameters, accurate model simulation, and application.
Mild and Efficient Preparation of N-Heterocyclic Organic Molecules by Catalyst-free and Solvent-free Methods
Authors: Wu Zhiqiang , Li Xuesong , Li Yueyi , Cao Lin-an , Li Zhenliang , Wang Xuming , Liu Wanyi , Feng Enke 
Published: February 2024

Aims:
The small organic molecular compounds with biological activity containing C-C and C-N or C-O bonding were efficiently prepared without catalyst and solvent in the hydrothermal synthesis reactor.

Objectives:
Our goal was to explore new applications for the more environmentally friendly and efficient synthesis of bis(indolyl)methyl, xanthene, quinazolinone, and N-heterocyclic derivatives in hydrothermal synthesis reactors under solvent-free and catalyst-free conditions.

Methods:
A greener and more efficient method was successfully developed for the synthesis of bis(indolyl)methyl, heteroanthracene, quinazolinone, and N-heterocyclic derivatives using a hydrothermal synthesis reactor in a solvent- and catalyst-free manner.

Results:
In a hydrothermal synthesis reactor, bis(indoyl)methyl, xanthene, quinazolinone, and N-heterocyclic derivatives were synthesized without catalysts and solvents.

Conclusion:
Overall, it is proved once again that the catalyst-free and solvent-free synthesis method has universal value and is a more ideal and environmentally friendly new method, especially the hydrothermal reactor for synthesis.
1,3-Diaryl Triazenes Incorporating Disulfonamides Show Both Antiproliferative
Activity and Effective Inhibition of Tumor-associated Carbonic Anhydrases IX and
XII
Authors: Lolak Nebih , Akocak Suleyman , Petreni Andrea , Budak Yakup , Bozgeyik Esra , Gurdere Meliha Burcu , Ceylan Mustafa , Supuran Claudiu Trandafir 
Published: February 2024

Aim:
The aim of this study was to synthesize a library of novel di-sulfa drugs containing 1,3- diaryltriazene
derivatives TS (1-13) by conjugation of diazonium salts of primary sulfonamides with sulfa drugs to investigate
the cytotoxic effect of these new compounds in different cancer types and to determine their inhibitory
activity against tumor-associated carbonic anhydrases IX and XII.

Materials and Methods:
A carbonic anhydrase inhibitory activity of the obtained compounds was evaluated
against four selected human carbonic anhydrase isoforms (hCA I, hCA II, hCA IX and hCA XII) by a stoppedflow
CO2 hydrase assay. In addition, in vitro, cytotoxicity studies were applied by using A549 (lung cancer),
BEAS-2B (normal lung), MCF-7 (breast cancer), MDA-MB-231 (breast cancer), CRL-4010 (normal breast epithelium),
HT-29 (colon cancer), and HCT -116 (colon cancer) cell lines.

Results:
As a result of the inhibition data, the 4-aminobenzenesulfonamide derivatives were more active than
their 3-aminobenzenesulfonamide counterparts. More specifically, compounds TS-1 and TS-2, both of which
have primary sulfonamides on both sides of the triazene linker, showed the best inhibitory activity against hCA
IX with Ki values of 19.5 and 13.7 nM and also against hCA XII with Ki values of 6.6 and 8.3 nM, respectively.
In addition, in vitro cytotoxic activity on the human breast cancer cell line MCF-7 showed that some derivatives
of di-sulfa triazenes, such as TS-5 and TS-13, were more active than SLC-0111.

Conclusion:
With the aim of developing more potent and isoform-selective CA inhibitors, these novel hybrid
molecules containing sulfa drugs, triazene linkers, and the classical primary sulfonamide chemotype may be
considered an interesting example of effective enzyme inhibitors and important anticancer agents.
Analysis of OTC and Prescribed Drugs Working Against COVID-19 Symptoms in the Context of Humans and Surrounding: A Brief Report on Medications Taken by Patients
Authors: Nagpal Kajal , Dhingra Ashwani , Handa Uditi , Deswal Geeta , Kriplani Priyanka , Guarve Kumar , Malik Anuj , Jan Fatimah , Dubey Abhilasha 
Published: February 2024

Background:
Coronaviruses are the genetic series of RNA viruses that infect both organisms
mammals and birds. Different varieties of illnesses shown in humans as well as in birds are the
most common causes ranging from minor to fatal. Common colds which are included in mild and
SARS, MERS, and COVID-19 are caused by fatal. After cell entry, the release of RNA into the cytoplasm
occurs, which translates viral proteins followed by processed replication.

Objective:
The survey was based on a comparison study between the purchase of OTC and prescribed
drugs for COVID-19 symptoms, including the volume of pharmacies from different zones of
Yamunanagar district, Haryana.

Methods:
The analytical survey involves the different zones of Yamunanagar the pharmacist used in
this report. The numerical data is gathered in a methodical investigation which leads to quantitative
research. The data investigation was performed by using Statistical Package for Social Sciences
(SPSS) version 20.

Results:
The north zone area mostly suffered from the COVID-19 pandemic condition from January
2021 to June 2021 in Yamunanagar and found that most of the OTC drugs purchased by consumers
were paracetamol (PCM) and Prescribed drugs (HQCS + Azithromycin) by the public regarding
covid-19 symptoms.

Conclusion:
The outcome of this case report reveals that no statistically significant difference exists
between the population parameter and sample statistics while the comparison retained the null hypothesis
in different zones of Yamunanagar (Haryana), India including the volume of pharmacy and
drug category.
EVALUATION OF THE ROLE OF FINE NEEDLE ASPIRATION CYTOLOGY IN DIAGNOSIS OF BREAST LESIONS AND CORRELATION WITH HISTOPATHOLOGICAL EXAMINATION
Authors: Dr Palak Patel  , Dr Harsh Pandya  , Dr Avani Dangar  , Dr Drashti Patel  , Dr Krishna Kant Shiromani  
Published: February 2024

Introduction : Breast carcinoma is one of the most common carcinomas among the women. FNAC is part of a TRIPLE APPROACH for the diagnosis of breast lumps:a) Clinical examination, b) Imaging and c) Biopsy (FNAC and Core biopsy).FNAC is considered as valuable diagnostic techniques because of its simplicity, reliability, cost- effectivity and with minimal complications.
Aims and Objectives : The aim of this study is to assess the accuracy of FNAC in diagnosis of breast lesions in correlation with histopathological findings.
Material and Methedology : This is retrospective study for a period of one year of all the cases of breast lesions that were referred to pathology department for FNAC and These patients were subjected to Excisional biopsy/Incisional biopsy/Mastectomy.

Result : In duration of 1 year of study, we received total 76 cases with complaint of breast lump. The frequency of benign breast lesions were higher in the range of 20-40 years and the frequency of malignant lesions were higher among the age group of 41-60 years. Out of 76 cases, 40 (52.6%) cases were of Fibroadenoma, 2 (2.6%) cases were of Abscess, 2 (2.6%) cases were of Fibrocystic disease, 2 (2.6%) cases were of lactating adenoma and 30 (39.5%) cases were of malignant lesion. Among total of 76 cases, 46 cases were non-malingant and 30 cases were malignant on cytological examination. 46 non-malignant cases diagnosed on FNAC were correlated with histopathology examination. 2 false negative cases were reported which were diagnosed as benign breast lesions turned out be malignant on histopathological examination. Out of 30 diagnosed malignant lesions on FNAC, all were consistent with histopathology examination. In our study, Incidence of Benign breast lesions is 57.9% and Malignant breast lesions is 39.5% respectively.
Conclusion : Our study states that reporting and findings of FNAC were closely correlated with the histopathological diagnosis in accordance to NCI guidelines. FNAC has significant diagnostic value in differentiating the breast lumps for further operative management.Awareness of breast cancer is must and much needed in developing country like India which can be achieved by proper education, prevention, early detection and proper management of breast lesions.
POTENTIAL DRUG-DRUG INTERACTIONS OF CARDIOVASCULAR DRUGS BASED ON LITERATURE IN GERIATRIC PATIENTS WITH CONGESTIVE HEART FAILURE AT Dr. M. DJAMIL PADANG HOSPITAL
Authors: PERMATASARI DITA , HUSNA NUR ALIMA , YOSMAR RAHMI 
Published: February 2024

Objective: Congestive Heart Failure (CHF) is a notable cardiovascular disease impacting global morbidity and mortality. Geriatric patients with CHF typically require multiple medications that can potentially cause drug-drug interactions and affect patient therapy outcomes. This study aims to determine the potential drug-drug interactions, the relationship between the average number of cardiovascular drugs per day and the potential drug-drug interactions, and the relationship between the severity of drug-drug interactions and the clinical symptoms and signs of the patients.
Methods: The research method used was analytical observational with retrospective data collection through the medical records of inpatients in 2021. A total of 63 patients were included using the total sampling method.
Results: Results revealed that furosemide was the most commonly prescribed cardiovascular medication (15.27%). Among the participants, 93.65% exhibited potential drug-drug interactions (332 occurrences), with the most frequent involving furosemide and bisoprolol (32 cases). Pharmacodynamic interactions were the dominant mechanism (85.24%), with moderate severity (65.06%) being common. A significant relationship existed between the average number of cardiovascular drugs per day and the potential drug-drug interactions (p<0.05). Nonetheless, there was no notable correlation discovered between the severity of the interaction and the presence of symptoms and clinical signs (p>0.05).
Conclusion: When considering the high incidence of potential drug-drug interactions, it is expected that clinical pharmacists have the competence to analyze potential drug interactions to prevent harmful effects on patients.
Development of a sales information system to improve Batik Shop’s sales efficiency
Authors: Prijambodo Bambang , Fajrin Ahmad Miftah , Susila Vikantya , Aziiza Arizia Aulia 
Published: February 2024

Abstract—Batik is an indigenous cultural artifact of Indonesia that demands conservation. This study's batik establishment, Satrio Manah Batik, is located in Tulungagung and specializes in selling authentic Tulungagung batik. Sales for Satrio Manah Batik are conventional, and customers must physically visit the store. Satrio Manah Batik often makes custom orders, so it takes time for an appointment. The sales reach is limited to Tulungagung, and transactions are restricted to clients already acquainted with Satrio Manah Batik. Further, the antiquated book writing method must still be employed to record raw material stocks and sales reports. There needs to be a better record of the product inventory reports. It affects the calculations of monthly sales profits. Hence, this study was conducted to develop a sales information system to improve Satrio Manah Batik's sales efficiency. This research was developed using a waterfall model. The verification and validation results show that the system developed can meet customer needs. Customers can order custom batik by platform in a short time, which can increase the effectiveness of Batik Satrio Manah's sales.
Keywords: sales information system, batik shop, efficiency

Abstrak—Batik merupakan artefak budaya asli Indonesia yang perlu dilestarikan. Tempat usaha batik pada penelitian ini adalah Batik Satrio Manah, yang berlokasi di Tulungagung dan khusus menjual batik asli Tulungagung. Penjualan Batik Satrio Manah bersifat konvensional dan pelanggan harus mengunjungi toko secara fisik. Satrio Manah Batik sering membuat pesanan secara custom sehingga memerlukan waktu untuk membuat janji. Jangkauan penjualan Batik Satrio Manah hanya terbatas di Tulungagung, dan pembeliaan hanya dilakukan oleh pelanggan yang sudah mengenal Satrio Manah Batik. Selain itu, cara mencatat stok bahan baku dan laporan penjualan masih melakukan penulisan buku. Perlu adanya pencatatan laporan persediaan produk yang lebih baik. Hal ini mempengaruhi perhitungan keuntungan penjualan bulanan. Oleh karena itu, penelitian ini dilakukan untuk mengembangkan sistem informasi penjualan untuk meningkatkan efisiensi penjualan Batik Satrio Manah. Penelitian ini dikembangkan dengan menggunakan model waterfall. Hasil verifikasi dan validasi menunjukkan bahwa sistem yang dikembangkan dapat memenuhi kebutuhan pelanggan. Pelanggan dapat memesan batik custom melalui platform dalam waktu singkat sehingga dapat meningkatkan efektivitas penjualan Batik Satrio Manah.
Kata kunci: sistem informasi penjualan, toko batik, efisiensi
Insect Biodiversity in Mangrove Area of Tatengesan Village, Pusomaen District in Southeast Minahasa, North Sulawesi
Authors: Rante Feby Febrianty Toding , Mokosuli Yermia Semuel , Setyawati Iriani , Tumbel Ferny Margo , Lawalata Helen Joan 
Published: February 2024

The existence of insects cannot be separated from the condition of their habitat. The mangrove area of ​​Tatengesan Village is one of the ecotourism site in Minahasa, North Sulawesi, that can support the survival of insects. This study aimed to determine the distribution and diversity of insects and the factors that influence the insect diversity in the mangrove area. The type of research used is descriptive quantitative research by conducting data collection activities, analyzing data and interpreting data with the aim of making a description of the events that occurred. The animals were exploratory collected by using insect nets (sweep net), beating cloth (beating), and bare hands (hand collecting). The results showed that there were 1225 individual insects consisting of 14 insect species, which were divided into 14 genera, 11 families and 6 orders of insects. The insect diversity index value was 0.27 which was classified as low. The dominance index value was 0.90 which was classified as high. The evenness index value was 0.10 which was classified as low.
Influence of Corporate Planning on Implementation of Tactical Decisions in the County Government of Nakuru, Kenya
Authors: Daniel Mbogo Ndiritu  , Dr. Florence Opondo  , Robert Mwebi  
Published: February 2024

The strategy-making process, which entails carrying out strategic decisions, includes tactical decision-making. In county governments, the execution of tactical decisions is susceptible to unanticipated occurrences such escalating developmental needs, shifting limitations, and erratic resource flows. The Department of Trade had allocated USD 674,000 worth of projects. However, none of them was actually carried out, according to the Auditor General's report for the financial year 2017–2018 for Nakuru County. Only two of the 47 counties in the report received an unqualified report. Failure is quite likely when decisions are not made and actions are not taken to manage the counties successfully and professionally. Since devolution began, it has come to light that many counties in Kenya perform poorly in terms of providing services despite rising pressure to do better. The goal of this study was to determine how corporate planning affects how well tactical decisions are implemented in the Kenyan County Government of Nakuru. The study adopted the descriptive research design whereby senior officers from the 10 Nakuru County government departments, heads of the 11 sub-counties, and the 55 ward managers made up the target population, which totaled 116 people, of whom 89 served as the study sample. The correlation analysis results revealed that there was a positive and a strong significant association between corporate planning and the implementation of tactical decisions (r=0.725, p=0.000<0.05). The hypothesis test results show that corporate planning statistically influences the implementation of tactical decisions (β = 0.647, ρ = 0.000< 0.05). The results imply that product diversification improves financial performance.
The study recommends that commercial banks involved in mergers and acquisitions since 2010 in Kenya make only minor adjustments to their existing operations as the current diversification measures have been successful.
الإيقاع الداخلي في شعر الشريف الرضي و محمد سعيد الحبوبي دراسة نقدية موازنة أنموذجاً
Authors: جاسم المجمعي مريم محمد , أسعد نرجس خلف , أحمد ميناس شهاب 
Published: February 2024

يشتمل هذا البحث على بيان "الموازنة النقدية" بين الشاعرين في(الإيقاع الداخلي) والكشف من خلالها عن مواطن التشابه بينهما في تلك النصوص الشعرية والحكم عليها وفق الأحكام النقدية ، فكان مدار البحث حول "الإيقاع الداخلي " لما له أهمية عند الشعراء الجاهليين ،وامتداداً إلى الشعر الحديث، نجد أن كلاهما أجادا في الإيقاع الداخلي إذ وجدنا أغلب مستوياته لها حضور عند الشاعرين فالتكرار بأنواعه، تكرار الحرف، وتكرار الكلمة، وتكرار العبارة أو الجملة موجود لديهما فالجناس بنوعية (التام وغير التام)، وأجادا في توظيفهما فضلاً عن توظيفهم الطباق(السلب، الايجاب) رد الإعجاز إلى الصدور ، فهذا يدل على قدرة الشاعرين وبراعتهم إذ تمثل عند الشاعرين حضوراً بارزاً في الإداء اللغوي والموسيقي .
التنويع الاقتصادي ودوره في التخفيف من آثار تقلبات أسعار النفط العالمية على الموازنة العامة في العراق للمدة 2004-2020
Authors: رسولي المعمار محمد مجيد 
Published: February 2024

يهدف البحث الحالي الى دراسة واقع حال الاقتصاد العراقي من خلال الموازنة العامة التي تشتمل على كل من الايرادات العامة والنفقات العامة، وسبل الخروج من السمة الريعية باعتماده بشكل كبير على الايرادات النفطية، وذلك من خلال اتباع سياسة التنويع الاقتصادي وتفعيل الايرادات غير النفطية وذلك بتنشيط وتطوير قطاعي الزراعة والصناعة وقطاع الخدمات فضلا عن اشراك القطاع الخاص جنباَ الى جنب مع القطاع العام. استخدم الباحث الاسلوب الوصفي التحليلي للتعامل مع المعلومات والبيانات المتعلقة بموضوع البحث عبر مدة زمنية محددة وهي (2004-2020)، والاستعانة بالتقارير المحلية والعربية والدولية الصادرة عن الأمم المتحدة والبنك الدولي ومسوحات وزارة التخطيط العراقية-الجهاز المركزي للإحصاء ووزارة المالية -دائرة الموازنة والدراسات السابقة ذات الصلة.
A case that encapsulates the challenges of being a neurosurgeon in war-torn countries: Perspectives from Iraq
Authors: Alfawares Yara , Ismail Mustafa , Ramanathan Vishan P. , Andaluz Norberto , Hoz Samer S. 
Published: February 2024

Background:
The provision of healthcare services in Iraq has been negatively affected by a lack of resources, strained healthcare infrastructure, and low patient socioeconomic status. This paper describes a case of multiple intracranial aneurysms (MIAs) that highlight the challenges of practicing vascular neurosurgery in Iraq.

Case Description:
A 57-year-old female presented with sudden-onset severe headache, photophobia, and drowsiness and was diagnosed with subarachnoid hemorrhage in the basal cistern. Despite international guidelines recommending urgent treatment for suspected ruptured intracranial aneurysms, the patient’s healthcare team in Babylon advised against a CT angiogram (CTA). The patient’s family took responsibility for transferring her to a private facility for a CTA, which showed four aneurysms. Due to financial constraints, the family opted for open surgery, during which a ruptured aneurysm was found and successfully managed. The remaining two aneurysms were monitored with serial follow-up imaging.

Conclusion:
The case highlights the challenges of practicing vascular neurosurgery in Iraq and the impact of financial constraints on the management of MIA. It emphasizes the need for increased resources and expertise in the country’s healthcare system to provide optimal care for patients with life-threatening conditions.