bluuebunny/crossref_metadata_2025_split huggingface dataset:
Exploring the Role of Mesenchymal Stem Cell–Derived Exosomes in Diabetic and Chemotherapy-Induced Peripheral Neuropathy
Authors: Ahmed Lamiaa A. , Al-Massri Khaled F. 
Published: January 2024

AbstractDiabetic and chemotherapy-induced peripheral neuropathies are known for long-term complications that are associated with uncontrolled hyperglycemia and cancer treatment, respectively. Peripheral neuropathy often requires long-term therapy and could persist after treatment provoking detrimental effects on the patient’s quality of life. Despite continuous drug discoveries, development of efficient therapies is still needed for the significant management of diabetic and chemotherapy-induced peripheral neuropathy. Exosomes are nanosized extracellular vesicles that show great promise recently in tissue regeneration and injury repair compared to their parent stem cells. Herein, we provided a summary for the use of mesenchymal stem cell–derived exosomes in diabetic and chemotherapy-induced peripheral neuropathy in addition to recent advancements and ways proposed for the enhancement of their efficacy in these diseases.
Graphical abstract
Photocatalytic degradation of methylene blue dye by magnetized TiO2-silica nanoparticles from rice husk
Authors: Popoola Lekan Taofeek , Yusuff Adeyinka Sikiru , Adejare Aderibigbe Tajudeen , Olasupo Sabitu Babatunde 
Published: January 2024

AbstractIn this current study, magnetized TiO2-supported SiO2 nanoparticles, synthesized from rice husk, was applied as a photocatalyst to degrade methylene blue dye (MBD) in aqueous solution using LED lamp as light source. The effects of MBD initial concentration, TiO2 loading, pH and illumination time on the degradation efficiency of the photocatalyst on MBD was investigated using Box–Behnken design as the experimental design tool. Photocatalyst was characterized by Fourier transform infrared, scanning electron microscopy, energy-dispersive X-ray, thermogravimetric analysis and Brunauer–Emmett–Teller. At optimum predicted point where MBD initial concentration, TiO2 loading, pH and illumination time were 10 ppm, 15%, 6 and 75 min, respectively, the predicted and experimental percentage of MBD removed were 97.66% and 96.89%, respectively. Correlation coefficient and ANOVA justified high significance of the developed model for prediction. Experimental data fitted excellently into pseudo-second-order kinetic model. The temperature effect revealed optimum MBD photocatalytic degradation at 50 °C by TiO2/mRH-SNP. Characterization revealed the effects of magnetization and TiO2 addition on the synthesized SiO2 nanoparticles from rice husk. In conclusion, magnetized TiO2-silica nanoparticles from rice husk could be effectively used to degrade MBD in solution.
Pain: its prevalence and correlates among the oldest old
Authors: Bokermann Josephine , König Hans-Helmut , Hajek André 
Published: January 2024

Abstract
Background
There is very limited knowledge regarding pain among the oldest old.

Aims
To investigate the prevalence and correlates of pain among the oldest old.

Methods
Data were taken from the “Survey on quality of life and subjective well-being of the very old in North Rhine-Westphalia (NRW80+)”, including individuals living in North Rhine-Westphalia aged 80 years and over. Pain was categorized as no pain, moderate pain and severe pain. Its prevalence was stratified by sex, age groups, marital status, place of residence and education. A multinomial logistic regression analysis was conducted.

Results
28.50% of the participants reported no pain, 45.06% moderate pain and 26.44% severe pain. Regressions showed that being 85 years or older and a better self-rated health status decreased the likelihood of moderate pain. Being 85–89 years old, being male, highly educated and a better self-rated health status decreased the likelihood of severe pain. The likelihood of moderate and severe pain increased with a higher number of chronic diseases.

Discussion
Study findings showed a high prevalence of pain in the oldest old living in North Rhine-Westphalia, Germany. The likelihood of having moderate or severe pain was reduced among those who were older and presented with a better self-rated health but increased with a growing number of comorbidities. Severe pain was less likely among men and those with a higher education.

Conclusion
This cross-sectional representative study adds first evidence of prevalence and correlations of pain among the oldest old. Longitudinal studies are required to further explore the determinants of pain in this age group.
Flexible, Transparent and Conductive Metal Mesh Films with Ultra-High FoM for Stretchable Heating and Electromagnetic Interference Shielding
Authors: Chen Zibo , Yang Shaodian , Huang Junhua , Gu Yifan , Huang Weibo , Liu Shaoyong , Lin Zhiqiang , Zeng Zhiping , Hu Yougen , Chen Zimin , Yang Boru , Gui Xuchun 
Published: January 2024

AbstractDespite the growing demand for transparent conductive films in smart and wearable electronics for electromagnetic interference (EMI) shielding, achieving a flexible EMI shielding film, while maintaining a high transmittance remains a significant challenge. Herein, a flexible, transparent, and conductive copper (Cu) metal mesh film for EMI shielding is fabricated by self-forming crackle template method and electroplating technique. The Cu mesh film shows an ultra-low sheet resistance (0.18 Ω □−1), high transmittance (85.8%@550 nm), and ultra-high figure of merit (> 13,000). It also has satisfactory stretchability and mechanical stability, with a resistance increases of only 1.3% after 1,000 bending cycles. As a stretchable heater (ε > 30%), the saturation temperature of the film can reach over 110 °C within 60 s at 1.00 V applied voltage. Moreover, the metal mesh film exhibits outstanding average EMI shielding effectiveness of 40.4 dB in the X-band at the thickness of 2.5 μm. As a demonstration, it is used as a transparent window for shielding the wireless communication electromagnetic waves. Therefore, the flexible and transparent conductive Cu mesh film proposed in this work provides a promising candidate for the next-generation EMI shielding applications.
A dual-function selection system enables positive selection of multigene CRISPR mutants and negative selection of Cas9-free progeny in Arabidopsis
Authors: Wang Feng-Zhu , Bao Ying , Li Zhenxiang , Xiong Xiangyu , Li Jian-Feng 
Published: January 2024

AbstractThe CRISPR/Cas9 technology revolutionizes targeted gene knockout in diverse organisms including plants. However, screening edited alleles, particularly those with multiplex editing, from herbicide- or antibiotic-resistant transgenic plants and segregating out the Cas9 transgene represent two laborious processes. Current solutions to facilitate these processes rely on different selection markers. Here, by taking advantage of the opposite functions of a d-amino acid oxidase (DAO) in detoxifying d-serine and in metabolizing non-toxic d-valine to a cytotoxic product, we develop a DAO-based selection system that simultaneously enables the enrichment of multigene edited alleles and elimination of Cas9-containing progeny in Arabidopsis thaliana. Among five DAOs tested in Escherichia coli, the one encoded by Trigonopsis variabilis (TvDAO) could confer slightly stronger d-serine resistance than other homologs. Transgenic expression of TvDAO in Arabidopsis allowed a clear distinction between transgenic and non-transgenic plants in both d-serine-conditioned positive selection and d-valine-conditioned negative selection. As a proof of concept, we combined CRISPR-induced single-strand annealing repair of a dead TvDAO with d-serine-based positive selection to help identify transgenic plants with multiplex editing, where d-serine-resistant plants exhibited considerably higher co-editing frequencies at three endogenous target genes than those selected by hygromycin. Subsequently, d-valine-based negative selection successfully removed Cas9 and TvDAO transgenes from the survival offspring carrying inherited mutations. Collectively, this work provides a novel strategy to ease CRISPR mutant identification and Cas9 transgene elimination using a single selection marker, which promises more efficient and simplified multiplex CRISPR editing in plants.
The Effect of Prone and Supine Limb Positioning on the Radiographic Evaluation of Posterolateral Plate Fixation of the Posterior Malleolus
Authors: Patel Preemal , Little Zoe , Beak Phillip , Williams Rachel , Trompeter Alex 
Published: January 2024

Abstract
Aim
To facilitate the posterolateral approach to the posterior malleolus patients are often positioned prone initially, then turned supine to complete fixation at the medial malleolus. We sought to define observed differences in the radiographic appearance of implants relative to the joint line, in prone and supine positions.

Methods
A 3.5 mm tubular plate and a 3.5 mm posterior distal tibial periarticular plate were applied sequentially to 3 individual cadaveric legs, via a posterolateral approach. The tubular plate was positioned to simulate buttress fixation and the posterolateral plate placed more distally. Each limb was secured on a custom jig and radiographs were taken on a mobile c-arm fluoroscopy machine with a calibration ball. A series of prone AP, supine PA and mortise radiographs were taken. Prone radiographs were also taken in different degrees of caudal tilt to simulate knee flexion which occurs in practice, during intraoperative positioning. Plate tip-joint line distances were measured and Mann–Whitney U tests performed.

Results
There was no statistically significant difference in plate tip-joint line distance when comparing equivalent prone and supine views (PA/AP or mortise). However, significant differences in apparent implant position were noted with alterations in caudal tilt. When taking a prone image, when the knee is flexed to 20 degrees, the plate tip will appear 6.5–8.5 mm more proximal than in the equivalent supine image where the knee is extended and the fluoroscopy beam is orthogonal to the anatomic axis of the tibia.

Conclusion
Observed differences in radiographic appearance of metalwork in the prone and supine position are most likely due to knee flexion and the resulting variation in the angle of the fluoroscopy beam, rather than projectional differences between supine and prone views. Surgeons should be alert to this when analysing intraoperative images.
Clustering graph data: the roadmap to spectral techniques
Authors: Mondal Rahul , Ignatova Evelina , Walke Daniel , Broneske David , Saake Gunter , Heyer Robert 
Published: January 2024

AbstractGraph data models enable efficient storage, visualization, and analysis of highly interlinked data, by providing the benefits of horizontal scalability and high query performance. Clustering techniques, such as K-means, hierarchical clustering, are highly beneficial tools in data mining and machine learning to find meaningful similarities and differences between data points. Recent developments in graph data models, as well as clustering algorithms for graph data, have shown promising results in image segmentation, gene data analysis, etc. This has been primarily achieved through research and development of algorithms in the field of spectral theory, leading to the conception of spectral clustering algorithms. Spectral clustering algorithms have been one of the most effective in grouping similar data points in graph data models. In this paper, we have compiled 16 spectral clustering algorithms and compared their computational complexities, after an overview of graph data models and graph database models. Furthermore, we provided a broad taxonomy to classify most existing clustering algorithms and discussed the taxonomy in detail.
Fat phobia scale-short form and beliefs about obese persons scale: cross-cultural adaptation to Brazilian Portuguese
Authors: de Souza Gabriela Cristina Arces , Laus Maria Fernanda , da Silva Wanderson Roberto , Japur Camila Cremonezi 
Published: January 2024

AbstractThe Fat Phobia Scale-Short Form (FPS) and the Beliefs About Obese Persons Scale (BAOP) are scales developed to investigate fatphobia and beliefs about obese persons, respectively. The aim of the study was to carry out the cross-cultural adaptation of these scales to Brazilian Portuguese. The methodology was carried out in 5 stages: 1. translation, 2. synthesis of translations, 3. evaluation by the expert committee of semantic, idiomatic, experiential and conceptual equivalences, 4. discussion with the target population (health professionals and other areas), and 5. back-translation. The results of the judgment of equivalences evaluated by the specialists were presented in absolute and relative frequency, and the agreement of the results between the specialists was verified by the Kappa de Fleiss Coefficient (₭). The results showed excellent agreement for all equivalences in both scales, except for BAOP semantics, which was good. (₭ = 0.67). Suggestions from the target population (Brazilian adults) were considered to adapt the final version of the two scales, which were back-translated and approved by the original authors. It is concluded that FPS and BAOP are duly adapted to Brazilian Portuguese and ready to be tested for their psychometric qualities.
Control-oriented planning and development-oriented planning: comparison of planning paradigms and practice in Hubei, China
Authors: Zheng Degao , Chen Ye , Luo Yan , Wang Jiuyu 
Published: January 2024

AbstractThe history of planning development in various countries shows that the core logic of planning is the spiral interweaving of control and development, and constantly makes corresponding adjustments to respond to changes and challenges in social and economic development. Most of the planning in western countries originated from control-oriented paradigm, then integrated development-oriented elements, and finally has evolved into comprehensive coordination-oriented planning paradigm. China’s planning, which originated from development-oriented paradigm, has shifted towards control-oriented planning as represented by territorial spatial planning to tackle issues such as excessive consumption of resources. In the face of economic, social and environmental challenges, China’s urban planning in the future should also move towards a comprehensive balance between control and development. The common thread of control is the sustainable development of economy, society, and environment. The common thread of development is to achieve the Chinese path to modernization. The content of control and development will vary with different spatial scales and time stages. Take Hubei’s practice as an example, planning control is driven by the integrated management of watershed and planning development is led by the synchronization of new industrialization, IT application, new urbanization, and agricultural modernization. Hubei Province seeks to promote high-quality, sustainable development through comprehensive coordination-oriented planning that combines control and development.
Properties and photosynthetic promotion mechanisms of artificial humic acid are feedstock-dependent
Authors: Li Xiaona , Zhi Yancai , Jia Minghao , Wang Xiaowei , Tao Mengna , Wang Zhenyu , Xing Baoshan 
Published: January 2024

AbstractThe artificial humic acids (AHA) approach contributes to achieving the carbon (C) emission peaking and neutrality goal through efficient recycling of waste biomasses and promotion of plant photosynthesis. However, the dependence of their production processes and photosynthetic promotion mechanisms on feedstocks remains unclear. In this study, waste biomasses including camphor leaves (CL), corn stalks (CS), peanut shells (PS), and mixed cyanobacteria (MC) have been respectively converted into artificial humic acids through an environmentally friendly hydrothermal humification approach. The dynamic humification process of different feedstocks and the composition, structural properties, and electron transfer capacity of AHA products were determined. Moreover, the different AHA products were applied to corn to explore their respective photosynthetic promotion mechanisms. High relative contents of lignin and C/N in feedstocks are not conducive to the formation of photodegradable substances and the redox property in AHA. The application of AHA increased the net photosynthetic rate and biomass C of corn by 70–118% and 22–39%, respectively. The AHA produced from higher H/C (0.19) and hemicellulose content (17.09%) in feedstocks (e.g., MC) increased corn photosynthesis by improving light energy capture and conversion efficiency in the PSII process. In contrast, the AHA produced from a higher content of lignin (19.81%) and C/N (7.67) in feedstocks (e.g., CS) increased corn photosynthesis by providing functional enzymes (proteins) and nutrients for leaves. This work provides new insights into the utilization of renewable resources, and the artificial humic acids approach sheds light on environmental sustainability by constructing a closed loop of C in environments.
Graphical Abstract
Biochar mitigates the mineralization of allochthonous organic matter and global warming potential of saltmarshes by influencing functional bacteria
Authors: Zhang Yiyi , Huang Yuzhou , Hu Jing , Tang Tao , Xu Caicai , Effiong Kokoette Sunday , Xiao Xi 
Published: January 2024

AbstractSaltmarshes are suffering from severe degradation due to anthropogenic activities, leading to the loss of blue carbon and greenhouse gas (GHG) emissions. Given the significant potential of biochar in mitigating climate change, adding biochar to saltmarshes would alleviate this situation. This study investigated the effects of different biochar (made from Spartina alterniflora, corn straw, and Laminaria japonica) and their aged biochar on the carbon fraction contents, GHG emissions, and microbial community structure of saltmarsh soils with allochthonous organic matter (Enteromorpha prolifera) addition. After 60 days of incubation, total organic carbon (TOC) loss and global warming potential (GWP) of biochar-amended soils were reduced by 67.29–124.33% and 4.91–123.24%, respectively (p < 0.05). Biochar reduced the proportion of labile carbon (dissolved organic carbon (DOC) and microbial biomass carbon (MBC)) in organic carbon by 61.92–86.15% (p < 0.05). In addition, biochar reduced the relative abundance of specific functional bacteria (inc. cellulolysis, aromatic compound degradation, and xylanolysis) involved in organic carbon decomposition by 20.02–37.82% (p < 0.05). These results suggest that even in the presence of high levels of liable organic matter, the application of biochar to saltmarshes has a sustained effect in promoting carbon accumulation and reducing GHG emissions, and this effect is regulated by a decrease of functional bacteria associated with carbon metabolism. Therefore, the in situ study of biochar on restoring carbon sink function of saltmarshes is proposed for practical engineering in future.
Graphical Abstract
Regulating oxygenated groups and carbon defects of carbon-based catalysts for electrochemical oxygen reduction to H2O2 by a mild and self-recycled modification strategy
Authors: Ma Chong , Hao Qing , Hou Jianhua , Liu Annai , Xiang Xu 
Published: January 2024

AbstractIt is a green route to prepare H2O2 through electrochemical oxygen reduction at normal temperature and pressure using only oxygen and water as feedstock. This method is suitable for the distributed production of H2O2, avoiding the safety problems caused by long-term storage and long-distance transportation. We propose a mild strategy modulating carbon materials i.e., the carbon black is treated by a low-concentration H2O2, where the oxidation reactions occur by hydroxyl radicals. The oxygenated groups and carbon defects were regulated by adjusting the concentration H2O2 used. The modified carbon black showed excellent selectivity and stability in the electrosynthesis of H2O2 under neutral conditions. The optimal catalyst had a selectivity of 99% for H2O2 at a potential of 0.25 V vs. reversible hydrogen electrode and remained above 90% in a wide potential window. The activity of optimal catalyst was increased by 19% compared to the pristine carbon black. It was found that the improvement of catalytic activity and selectivity was mainly ascribed to carbon defect. The concentration of H2O2 produced was 0.33 mol L−1 with 80% Faradaic efficiency at 4.5 V in the flow cell. The productivity of H2O2 could reach 2.23 mol g−1 h−1 during a continuous operation of 10 h.
Graphical Abstract
Examining the contributions of muslim women in achieving sustainable development goals in Nigeria
Authors: Fahm AbdulGafar Olawale , Memud Suliat Yetunde 
Published: January 2024

AbstractThe study aims to investigate the often underestimated role of Muslim women in the context of Nigeria in advancing Sustainable Development Goals (SDGs). The methodology employed in this research involves qualitative methods, allowing for an in-depth exploration of the multifaceted contributions of Muslim women in areas such as education, healthcare, gender equality, poverty reduction, and community development. Data for this study was obtained through interviews and surveys involving Muslim women from various regions in Nigeria, facilitating a comprehensive understanding of their roles, challenges, and strategies. The data was meticulously analyzed to identify the challenges faced by these women, the innovative strategies they employ to overcome these challenges, and the tangible impact of their efforts on the progression of SDGs in Nigeria. The findings of this research highlight the pivotal role of Muslim women in sustainable development and emphasize the need for recognizing and empowering them as catalysts for positive change. This recognition, in turn, is seen as a catalyst for broader inclusivity and gender equity initiatives, both within Nigeria and beyond, with the ultimate goal of achieving SDGs in a more comprehensive and inclusive manner.
Correlating real-world incidents with vessel traffic off the coast of Hawaii, 2017–2020
Authors: Henriksen Amelia 
Published: January 2024

Abstract
Objectives
Because of the high-risk nature of emergencies and illegal activities at sea, it is critical that algorithms designed to detect anomalies from maritime traffic data be robust. However, there exist no publicly available maritime traffic data sets with real-world expert-labeled anomalies. As a result, most anomaly detection algorithms for maritime traffic are validated without ground truth.

Data description
We introduce the HawaiiCoast_GT data set, the first ever publicly available automatic identification system (AIS) data set with a large corresponding set of true anomalous incidents. This data set—cleaned and curated from raw Bureau of Ocean Energy Management (BOEM) and National Oceanic and Atmospheric Administration (NOAA) automatic identification system (AIS) data—covers Hawaii’s coastal waters for four years (2017–2020) and contains 88,749,176 AIS points for a total of 2622 unique vessels. This includes 208 labeled tracks corresponding to 154 rigorously documented real-world incidents.