bluuebunny/crossref_metadata_2025_split huggingface dataset:
Quality of Life in Patients With Newly Diagnosed Chronic Phase Chronic Myeloid Leukemia on Imatinib Versus Interferon Alfa Plus Low-Dose Cytarabine: Results From the IRIS Study
Authors: Hahn Elizabeth A. , Glendenning G. Alastair , Sorensen Mark V. , Hudgens Stacie A. , Druker Brian J. , Guilhot Francois , Larson Richard A. , O’Brien Stephen G. , Dobrez Deborah G. , Hensley Martee L. , Cella David 
Published: May 2003

Purpose: Quality of life (QOL) outcomes in patients with chronic myeloid leukemia (CML) were evaluated in an international phase III study. Patients and Methods: Newly diagnosed patients with chronic phase CML were randomly assigned to imatinib or interferon alfa plus subcutaneous low-dose cytarabine (IFN+LDAC). Cross-over to the other treatment was permitted because of intolerance or lack of efficacy. Patients completed cancer-specific QOL (Functional Assessment of Cancer Therapy–Biologic Response Modifiers) and utility (Euro QoL-5D) questionnaires at baseline and during treatment (n = 1,049). The primary QOL end point was the Trial Outcome Index (TOI; a measure of physical function and well-being). Secondary end points included social and family well-being (SFWB), emotional well-being (EWB), and the utility score. Primary analyses were intention to treat with secondary analyses accounting for cross-over. Results: Patients receiving IFN+LDAC experienced a large decline in the TOI, whereas those receiving imatinib maintained their baseline level. Treatment differences at each visit were significant (P < .001) and clinically relevant in favor of imatinib. Mean SFWB, EWB, and utility scores were also significantly better for those patients taking imatinib. Patients who crossed over to imatinib experienced a large increase in TOI; significant (P < .001) differences were observed between patients who did and did not cross over in favor of imatinib. Conclusion: Imatinib offers clear QOL advantages compared with IFN+LDAC as first-line treatment of chronic phase CML. In addition, patients who cross over to imatinib from IFN+LDAC experience a significant improvement in QOL compared with patients who continue to take IFN+LDAC.
Microporous Structure of a Chain Compound of Copper(II) Benzoate Bridged by Pyrazine
Authors: Nukada Ryoji , Mori Wasuke , Takamizawa Satoshi , Mikuriya Masahiro , Handa Makoto , Naono Hiromitsu 
Published: June 2003

Abstract
Reaction of copper(II) benzoate with pyrazine (pyz) gave a compound, [Cu2(bz)4(pyz)]n (1) which has a gas-occlusion property. The X-ray structure analysis of 1·2nCH3CN shows a microporous structure formed by chains where the carboxylate dimer units are linked by pyrazine molecules.
FT-IR External Reflection Spectroscopy Study on Photochromic Monolayers at the Air-Water Interface
Authors: Kawai Takeshi , Hane Ryoichi , Ishizaka Fumitoshi , Kon-No Kijiro 
Published: June 2003

Abstract
Photoresponse behavior of azobenzene containing fatty acid in Langmuir (L) film was investigated using FT-IR and UV-vis spectra. Irradiation of UV or visible light resulted in reversible photoisomerization of the fatty acid in L film. The orientational change in the alkyl chain of the fatty acid in L film was determined in situ by FT-IR external reflection spectra, and the effect of the surface area on these changes is discussed.
Influences of Initial Particle Size on Preparation of Monodisperse CdS Nanoparticles with Size-Selective Photoetching
Authors: Torimoto Tsukasa , Kontani Hironori , Sakata Takao , Mori Hirotaro , Yoneyama Hiroshi 
Published: June 2003

Abstract
It was found that the size-selective photoetching of CdS particles prepared in Nafion films could be achieved only for particles having the particle sizes smaller than about 12 nm in the diameter. The particles greater than this threshold size were photocorroded until complete dissolution was attained.
New Positive-Type Photosensitive Poly(phenylene ether): Poly(2-hydroxy-6-methylphenol-co-2,6-dimethylphenol) with Diazonaphthoquinone
Authors: Takeshi Kazumasa , Okuyama Ken-ichi , Ohba Yoshihiro , Ueda Mitsuru 
Published: June 2003

Abstract
A positive working thermally stable and photosensitive polymer based on poly(2-hydroxy-6-methylphenol-co-2,6-dimethyl phenol) (PHP-MP) and 2,3,4-tris[2-diazo-1(2H)-naphthalenone-4-sulfonyloxy] benzophenone (D4SB) as a photoreactive compound has been developed. The copolymer PHP-MP was prepared by oxidative coupling polymerization of 2-(tetrahydropyran-2-yl)oxy-6-methylphenol with 2,6-dimethylphenol, followed by acid treatment. The PHP-MP film showed excellent transparency above 300 nm. A clear positive pattern was obtained when it was exposed to 365 nm light, followed by developing with a 2.38% aqueous tetramethylammonium hydroxide (TMAH) solution at 25 °C.
Structure and Natural Bond Orbital Analysis of Oxiranes Substituted with a Group 14 Element. A Comment of SN2 Regioselectivity
Authors: Ikeno Taketo , Harada Jun , Tomoda Shuji 
Published: June 2003

Abstract
Crystal structure analysis of oxiranes substituted with a group 14 element revealed that silyl and stannyl groups lengthened their α C–O bonds. Natural bond orbital analysis showed that silyl group raised the energy level of α C–O σ orbital and lowered that of α C–O σ* orbital. It was suggested that the former might lengthen the α C–O bond and that the latter should affect the regioselectivity in ring-opening reactions.
Microparticles and Colloidal Dispersions of Poly(3-hexylthiophene)
Authors: Takeuchi Hisao , Kobashi Masahiro 
Published: June 2003

Abstract
Stable colloidal dispersions of poly(3-hexylthiophene) have been successfully obtained by a simple precipitation technique with selected poor solvents. Dynamic light scattering measurement revealed that the colloidal particles of poly(3-hexylthiophene) have the hydrodynamic radius of 20-40 nm with a narrow particle size distribution. The particle size can be controlled by the precipitation conditions.
Control of Reductive Elimination and Acidolysis of Diarylnickel(II) Complexes by the Kind of Brønsted Acid and the Presence of Oxygen
Authors: Yamamoto Takakazu , Murakami Yasuharu , Abla Mahmut 
Published: June 2003

Abstract
Reaction of NiAr2(bpy) (Ar = electron withdrawing aryl group, bpy = 2,2′-bipypridyl) with Brønsted acids leads to reductive elimination of Ar-Ar from NiAr2(bpy). The reaction also causes acidolysis of the Ni complex depending on the kind of the acid and reaction conditions.
ET(30) Values of AOT Reverse Micelles Prepared in Supercritical Ethane
Authors: Shervani Zameer , Ikushima Yutaka 
Published: June 2003

Abstract
The ET(30) values in the core region of water/AOT/SC ethane micelles were determined for the first time as functions of pressure and water content of micelles (W0, [H2O]/[AOT]) at 310 K. The ET(30) values increased with increasing W0, but remained independent of pressure after system changed to a homogeneous micellar solution. The ET(30) values ranging from that observed in pure ethanol to 1,3-propanediol were obtained, with increasing W0 from 1 to 8.
Intramolecular Fluorescence Quenching in Ferrocene-Naphthalimide Dyads
Authors: Wang Zhaohui , Chen Kongchang , Tian He 
Published: June 2003

Abstract
The intramolecular fluorescence quenching in ferrocenoyl naphthalimide dyads has been studied. In the dyads, the singlet excited state of naphthalimide (NA) could be effectively quenched by the ferrocene center. When ferrocene (Fc) was oxidized chemically, the intramolecular electron transfer from the oxidized ferrocene (Fc+) would be inhibited and the fluorescence of NA moiety would be recovered.
Photo-Regulation of RNA Hydrolysis by the Zinc(II) Complex Carrying Azobenzene
Authors: Sumaoka Jun , Kawata Kentaro , Komiyama Makoto 
Published: June 2003

Abstract
The first photo-regulation of non-enzymatic RNA hydrolysis has been achieved. A positively-charged and bulky regulator has been linked to a catalytically active Zn(II) complex, via a photo-responsive linker involving an azobenzene. The rate of RNA hydrolysis has been reversibly modulated by photo-irradiation.
Synthesis of Carboxylic Acids through the Formation of C–C Bond between Saturated Hydrocarbons and CO in the Presence of Mg/K2S2O8/TFA System
Authors: Asadullah Mohammad , Kitamura Tsugio , Fujiwara Yuzo 
Published: June 2003

Abstract
Magnesium powder (Mg) promoted the carboxylation reaction of saturated hydrocarbons with carbon monoxide (CO) in the presence of potassium peroxodisulfate (K2S2O8) in trifluoroacetic acid (TFA) to yield the corresponding carboxylic acids and alkyl trifluoroacetates. About 80% conversion of cyclohexane was achieved when 5 mmol of magnesium, 5 mmol of potassium peroxodisulfate, 3 mL of TFA, 1 mmol of cyclohexane, 50 atm of CO were used at 80 °C for 30 h.
A Convenient Synthesis of Alkyl Substituted p-Benzoquinones from Phenols and H2O2 over TiAPO-5 Molecular Sieve Catalyst
Authors: Mahalingam Rathinam J , Selvam Parsuraman 
Published: June 2003

Abstract
Titanium substituted aluminophosphate (TiAPO-5) molecular sieves catalyze the oxidation reaction of alkyl substituted phenols with aqueous H2O2 in acidic medium to give the corresponding p-benzoquinones, in a single step, in high yield.
Synthesis of Tetrahydroindole Derivatives Using Titanium-Nitrogen Complexes Derived from Molecular Nitrogen
Authors: Akashi Masaya , Nishida Mayumi , Mori Miwako 
Published: June 2003

Abstract
Synthesis of tetrahydroindole derivatives was realized from keto-alkyne using titanium-nitrogen complexes generated from Ti(OiPr)4, Li, and TMSCl. In this reaction, the electron-withdrawing group on the alkyne gave a good yield, and keto-alkynes having an aromatic ring on the alkyne also gave tetrahydroindole derivatives in good to moderate yields.
Preparation of Novel Hollow Fiber Silica Using Collagen Fibers as a Template
Authors: Ono Yoshiyuki , Kanekiyo Yasumasa , Inoue Kazuhiko , Hojo Junichi , Nango Mamoru , Shinkai Seiji 
Published: June 2003

Abstract
A novel fibrous silica with a gnarled surface structure and an inner tube with bundle-replicated stripes was prepared by sol-gel polymerization of tetraethoxysilane using collagen fibers as a template.
Syntheses of Diruthenaborane Clusters, [{Cp*Ru(μ-H)}2B3H7], [{(Cp*Ru)2(μ-H)}B4H9], and [(Cp*Ru)2(μ-H)(PMe3)(μ-η4-B2H5)]
Authors: Kawano Yasuro , Matsumoto Hideyuki , Shimoi Mamoru 
Published: June 2003

Abstract
A diruthenapentaborane cluster [{Cp*Ru(μ-H)}2B3H7] (1) was synthesized by the reaction of [Cp*RuCl]4 with BH3·THF. Compound 1 undergoes cluster expansion by further interaction with BH3·THF to give [{(Cp*Ru)2(μ-H)}B4H9] (2). Reaction of 1 with PMe3 leads to degradation of the cluster framework to give [{(Cp*Ru)2(μ-H)}(PMe3)(μ-η4-B2H5)] (3).
Calix[4]arene Having a Convergent Carboxylic Acid Function: Synthesis and Ion Binding Properties of a New Cs+-selective Ionophore
Authors: Cho Hyun Jae , Kim Ji Young , Chang Suk-Kyu 
Published: June 2003

Abstract
Calix[4]arene bearing a convergent carboxylic acid function employing the Kemp’s triacid motif exhibited a pronounced selective ionophoric behavior toward Cs+ over other alkali metal ions. The selectivities of calix[4]arene-acid for Cs+ over Rb+, K+, and Na+ ions assessed by competitive transport experiments were 7.9, 26, and 121, respectively.
Synthesis of Linear Fullerene-Containing Polysiloxanes and Their Application to Capillary Gas Chromatography
Authors: Yuanyin Chen , Pengfei Fang , Zhaorui Zeng , Jianhong Fan 
Published: June 2003

Abstract
Fullerene-containing polysiloxanes were prepared by reacting [60]fullerene with azidoalkyl polysiloxanes directly, and characterized by FT-IR, UV-Vis, 1H-NMR and 13C-NMR. The polymers were used as stationary phases in capillary gas chromatography. Many organic compounds, especially high boiling substance or aromatic or alcohol positional isomers, were separated effectively on these columns.
Synthesis and Electroluminescence of Novel Copolymers with Charges Transporting Moieties
Authors: Zhu Weihong , Tian He , Elschner Andreas 
Published: June 2003

Abstract
The synthesis of novel copolymers, in which the electron transporting unit (oxadiazole), hole transporting unit (carbazole) and emitter (naphthalimide) are incorporated into one copolymer, has been reported. It was demonstrated that EL spectra of device made by these copolymers has a broad luminescent spectrum with range of 450-650 nm, which can be quantified in CIE coordinates as x = 0.32 and y = 0.37.
Salt Formation in the Langmuir-Blodgett Films of Arachidic Acid Mixed with Amphiphilic Ammonium Ions and an Amphiphilic Amine
Authors: Mutsuzaki Hisaaki , Azumi Reiko , Tachibana Hiroaki , Sakai Hideki , Abe Masahiko , Matsumoto Mutsuyoshi 
Published: June 2003

Abstract
In the Langmuir-Blodgett (LB) films of arachidic acid (AA) mixed with amphiphilic ammonium ions or an amphiphilic amine, AA was mixed with the second component at the molecular level and formed salt when the fraction of AA was not larger than 0.5. Further the fraction of the second component in the mixed LB films was smaller than that in the spreading solution with the fraction of the second component larger than 0.5.
New Catalyst of γ-Al2O3 Supported SO42− /ZrO2 for n-Butane Isomerization
Authors: Lei T , Xu J S , Gao Z 
Published: June 2003

Abstract
A series of new catalysts γ-Al2O3 supported SO42−/ZrO2 was prepared by the modified impregnation method using Zr(NO3)4 decomposition on a γ-Al2O3 carrier. The most active sample 60%SZ/Al2O3 is not only low expensive compared to the traditional bulk SZ due to the high price of ZrO2, but also increases the steady activity about 50% for n-butane isomerization in the presence of H2 at 523 K in comparison with the bulk SZ catalyst.
Effect of Pt Precursors on N2/N2O Selectivity for Selective Reduction of NO by Hydrocarbon on Supported Pt Catalysts
Authors: Doumeki Reiko , Hatano Masaharu , Kinoshita Hiroo , Yamashita Emi , Hirano Masafumi , Fukuoka Atsushi , Komiya Sanshiro 
Published: June 2003

Abstract
Selective catalytic reduction of NO by C3H6 has been studied for supported Pt catalysts prepared from organoplatinum complexes and an inorganic platinum salt. N2/N2O selectivity is improved by using the organoplatinum complexes as precursors at similar maximum conversions of NOx to N2 and N2O for the catalysts tested.
A Convenient Synthesis of a Ru(bpy)3-based Catenane-type Triad and Its Incorporation into a Protein Scaffold
Authors: Hu Yi-Zhen , Tsukiji Shinya , Shinkai Seiji , Hamachi Itaru 
Published: June 2003

Abstract
A catenated heme cofactor consisting of a donor (protoheme), a sensitizer (Ru(2,2′-bipyridine)3) and an acceptor (cyclobis(paraquat-p-phenylene) was prepared by stepwise coordination, followed by iron-insersion. Reconstitution of apo-myoglobin with this cofactor afforded a protein-based, noncovalently-linked photosynthetic triad.
Successive Flow-injection Determination of Iron(III) and Copper(II) by Means of the Effect of Activators
Authors: Watanabe Tsuyako , Teshima Norio , Kurihara Makoto , Nakano Shigenori , Kawashima Takuji 
Published: June 2003

Abstract
A novel flow-injection (FI) photometric method has been proposed for the successive determination of iron(III) and copper(II). It is based on the effect of activators such as 1,10-phenanthroline and 2,9-dimethyl-1,10-phenanthroline (neocuproine) on iron- and copper-catalyzed oxidative coupling of p-anisidine with N,N-dimethylaniline in the presence of hydrogen peroxide. By injecting two activators, alternatively, into the FI system, iron(III) (50–200 ng cm−3) and copper(II) (5–20 ng cm−3) can be selectively determined.
A Facile Synthesis of Optically Active 1,1,1-Trifluoro-3-alkyn-2-ols by Stereospecific Substitution of Optically Active 1-Benzyloxy-2,2,2-trifluoroethyl Tosylate with Lithium Alkynyltriethylaluminates
Authors: Matsutani Hiroshi , Kusumoto Tetsuo , Hiyama Tamejiro 
Published: June 2003

Abstract
Optically active 1-benzyloxy-2,2,2-trifluoroethyl tosylate reacts with various lithium alkynyltriethylaluminates to give optically active 2-benzyloxy-1,1,1-trifluoro-3-alkynes selectively and stereospecifically with inversion of configuration. Thus, the reaction provides with a novel method for the preparation of various optically active 1,1,1-trifluoro-3-alkyn-2-ols.
Synthesis and Characterization of a Novel Linear Conjugated Polymer, Poly(2,5-didodecyloxy-1,4-phenyleneoctatetraynylene)
Authors: Kijima Masashi , Kinoshita Ikuo , Shirakawa Hideki 
Published: June 2003

Abstract
A novel linear conjugated polymer, poly(2,5-didodecyloxyphenyleneoctatetraynylene), was synthesized by an oxidative coupling of 2,5-didodecyloxy-1,4-dibutadiynylbenzene in presence of a CuCl-TMEDA catalyst under O2 . The polymer was stable under air and soluble in organic solvents. The structural analyses and the characterizations were carried out by Raman, NMR, and UV-Vis.
Chemiluminescence Imaging of Localized Enzymes by Scanning Chemiluminescence Microscopy
Authors: Kasai Shigenobu , Zhou Huafang , Matsue Tomokazu 
Published: June 2003

Abstract
A novel scanning chemiluminescence microscopy (SCLM) was used for imaging localized horse radish peroxidase (HRP) or glucose oxidase (GOD) immobilized at a solid substrate. SCLM equips a scanning capillary tip (diameter, 1 μm) for injecting a small amount of luminol onto the substrate to generate localized chemiluminescence. The chemiluminescense induced by the enzyme-catalyzed reaction was detected with a photon-counter. Two-demensional mapping of the photon-counting intensity against the tip position gave images indicating the activity of immobilized HRP and GOD.
Evaluation of Rate Constant for Electron Transfer from C60-Anion Radical to Molecular Oxygen by Laser Flash Photolysis Method
Authors: Konishi Toshifumi , Fujitsuka Mamoru , Ito Osamu 
Published: June 2003

Abstract
The rate constant for electron transfer from C60-anion radical (C60•−) to molecular oxygen was evaluated to be (3.7 ± 0.2) × 102 mol−1 dm3 s−1 in benzonitrile by following the concentration of the C60•− by laser flash photolysis with a detector in the near-IR region for long time scale (&gt; 0.1 s).
Vapor-Phase Synthesis of Symmetric Ketone from Alcohol over CeO2-Fe2O3 Catalysts
Authors: Kamimura Yoichiro , Sato Satoshi , Takahashi Ryoji , Sodesawa Toshiaki , Fukui Masahiro 
Published: June 2003

Abstract
Formation of 3-pentanone via oxidative dimerization of l-propanol was investigated over CeO2-based solid solution with various metal oxides. An addition of Fe2O3 into CeO2 greatly enhanced the 3-pentanone formation, and both l-propanol conversion and 3-pentanone selectivity were maximized at Fe content of 20 mol%. It was found that the CeO2-Fe2O3 effectively works as a catalyst for the formation of symmetric ketones such as 3-pentanone, 4-heptanone, 5-nonanone, etc.
Photoredox Ability of a Hexarhenium(III) Cluster [Re6(μ3-S)8Cl6]4−
Authors: Kobayashi Natsuki , Ishizaka Shoji , Yoshimura Takashi , Kim Haeng-Boo , Sasaki Yoichi , Kitamura Noboru 
Published: June 2003

Abstract
The photoredox ability of a hexarhenium(III) cluster, (n-Bu4N)44+[Re6(μ3-S)8Cl6]4−, was examined in acetonitrile on the basis of emission quenching experiments of the cluster by several neutral electron acceptors. The quenching rate constants and the relevant activation parameters indicated that the hexarhenium(III) cluster acted as a useful photoredox sensitizer towards various electron acceptors.
Photo-induced Orientational Change in Langmuir-Blodgett Films of Azobenzene Complexed with Polyviologen
Authors: Tachibana Hiroaki , Yoshino Norio , Matsumoto Mutsuyoshi 
Published: June 2003

Abstract
We have demonstrated a new type of cis-trans isomerization of azobenzene in the complex LB films of amphiphilic azobenzene and polyviologen. This was accompanied by the changes in the orientation and the electronic state of azobenzene. The molecular orientation of azobenzene can be controlled by cis-trans photoisomerization.
Formation of Supermolecule by Assembling of Two Different Silanols
Authors: Unno Masafumi , Takada Keisuke , Matsumoto Hideyuki 
Published: June 2003

Abstract
The hydrogen bonding between cis,cis,cis-1,3,5,7-tetrahydroxy-1,3,5,7-tetraisopropylcyclotetrasiloxane and diisopropylsilanediol results in the formation of a nano-sized tube-like aggregate. The outer diameter of the aggregate was 11.6 Å and the tube-like structure extended infinitely parallel to the ac plane.
Palladium-Catalyzed Dehydrogenative Polymerization between Hydrosilanes and Quinones or Hydroquinone
Authors: Reddy Poreddy Narsi , Chauhan Bhanu Pratap Singh , Hayashi Teruyuki , Tanaka Masato 
Published: June 2003

Abstract
Dehydrogenative copolymerization between dihydrosilanes or a trihydrosilane and quinones proceeded in the presence of PdCl2(Pet3)2 as catalyst to give poly[(arylenedioxy)(silylene)]s.
Ethanol Cluster Formation on Silicon Oxide Surface in Cyclohexane–Ethanol Binary Liquids
Authors: Mizukami Masashi , Kurihara Kazue 
Published: June 2003

Abstract
Adsorption of ethanol onto silicon oxide surfaces from cyclohexane–ethanol binary liquids was investigated by FTIR spectroscopy using the attenuated total reflection (ATR) mode. ATR spectra exhibited that ethanol adsorbed on the surfaces formed clusters even in a low ethanol concentration range of 0.1–0.5 mol% where practically no ethanol cluster formed in the bulk solutions. The spectra indicated that the cluster formation involved hydrogen bonding interactions between surface silanol groups and ethanol hydroxyl groups in addition to those between ethanol hydroxyl groups.
Synthesis of the Water-Soluble, Electrically Conducting Poly(5-Aminonaphthalene-2-sulfonic Acid)
Authors: Atkinson S , Chan H S O , Neuendorf A J , Ng S C , Ong T T , Young D J 
Published: June 2003

Abstract
Poly(5-aminonaphthalene-2-sulfonic acid) 2 can be prepared by oxidative polymerisation of 5- or 8-aminonapthalene-2-sulfonic acid (1a, 1b) with Na2S2O8 or KIO4. This polymer is water soluble, electrically conducting and fluorescent.
Folding Properties of Cytochrome c Studied by Photocleavable o-Nitrobenzyl Modification of Methionine 65 and 80
Authors: Okuno Takashi , Hirota Shun , Yamauchi Osamu 
Published: June 2003

Abstract
Folding properties of cytochrome c (cyt c) were studied by specific o-nitrobenzyl modification of its methionines and subsequent UV light irradiation. Absorption changes with time scales of about 50 µs, 10 ms, 30–100 ms, and 250–500 ms were observed during folding of cyt c.
Chiral Amplification in Columns of Self-Assembled N,N′,N″-Tris((S)-3,7-dimethyloctyl)benzene-1,3,5-tricarboxamide in Dilute Solution
Authors: Brunsveld L , Schenning APHJ , Broeren MAC , Janssen HM , Vekemans JAJM , Meijer EW 
Published: June 2003

Abstract
Remarkable control of chirality within a long and stable columnar self-assembly of N,N′,N″-Tris((S)-3,7-dimethyloctyl)benzene-1,3,5-tricarboxamide in dilute solution is achieved by strong, unidirectional hydrogen bonding and cooperative side-chain interactions; IR and CD-spectroscopy have been used to elucidate these features.