bluuebunny/crossref_metadata_2025_split huggingface dataset:
Whether Stalin was a Fiery Revolutionary, or the Leader&#x27;s “Creative Response” from the Perspective of the Confrontation of Civilizations
Authors: Khrenov N.A. 
Published: February 2024

This publication is a fragment of a planned, extensive and not yet fully published study on the destiny of Russia as a unique civilization. The focus of the study is on the biographies of famous people whose activities have left a significant mark on the history of Russia, including politicians, scientists and artists. The book examines the biographies of F. Dostoevsky, M. Gorky, A. Solzhenitsyn, I. Stalin, L. Gumilev, A. Tarkovsky, and others. The fragment of the manuscript published in this issue of the journal examines the activities of Stalin. The peculiarity of Stalin&#x27;s activity is usually associated exclusively with the history of revolution, collectivization, modernization, etc., i. e. it is considered within the boundaries of the national political history and the named processes. The attention of those writing about Stalin is entirely determined by the Russian revolution of 1917 as one of the most significant events of the twentieth century and its consequences that determine the construction of a new society and state. However, there is a need – and it arises precisely in the first decades of the 21st century – to try to understand the leader&#x27;s activity at the level of the problem identified by S. Huntington in the title of one of his books, i. e. as “the clash of civilizations”. In other words, the leader&#x27;s activity can be viewed not in the context of the history of the revolution and the history of the Soviet state with their inherent positive and negative manifestations, but in the context of history as the history of civilizations, i. e. in the paradigm set by historians such as, for example, A. Toynbee. The conclusions and conclusions made by the author in this article are not taken in order to divert from Stalin all the criticism against him that has taken place since the era of the thaw and the subsequent thaw – perestroika. But this does not negate the significance of the creative response given by the leader to those Challenges that could have been dramatic for Russian civilization at that time. However, by giving such a “creative response” at that time, the leader did not solve the questions for the rest of his life at all. That time has passed, and Russia is again facing Challenges. It is up to us to give new creative responses to them, and we would like them to be correct.
Image-based sensing of salt stress in grapevine
Authors: Montanaro Giuseppe , Briglia Nunzio , Petrozza Angelo , Carlomagno Antonio , Rustioni Laura , Cellini Francesco , Nuzzo Vitale 
Published: February 2024

Grapevine is among the most economically important crops suffering environmental constraints, including drought and salt stress. Although imaging is increasingly used to detect abiotic stress in agriculture, image-based phenotyping in grapevine still needs optimisation. This study presents the RGB-(red, green, blue)-based phenotyping of the early stage of salt stress response in potted grapevine (Aleatico/SO4) irrigated with saline water (100 mM NaCl) for 9 days in contrast with vines irrigated with fresh water. The response was measured using stomatal conductance (gs), net photosynthetic rate (A), transpiration (E), maximum potential photosynthetic efficiency (Fv/Fm), stem water potential (SWP) concurrently with RGB imaging via a robotised platform.The image-based phenotyping of salt-stressed vines employed two sets of measurements: (i) the pixel fraction of specific colour bands (Yellow, Green, Brown and Dark Green) and (ii) the mean pixel value of R, G and B and other RGB-based colorimetric indexes. Results show that the responses of gs, A, E, Fv/Fm were closely related to increasing soil electrical conductivity (EC) and that imaging could detect the EC threshold of approx. 4 dS m-1 causing a ~60 % decrease in these physiological traits compared to the pre-stress level. The SWP declined to about –0.7 MPa at the end of the experiment. The change of the relative pixel fraction of Dark Green to increasing EC has been analysed within a dose-response context, showing that a decrease of 1 % of the Dark Green colour band corresponded to the 4 dS m-1 EC threshold. This study also examined the use of the mean pixel value of the R, G and B channels as proxies of EC along with new RGB-based indexes resulting from the rearrangement of original R, G and B mean pixel values. Results show the suitability of the mean pixel value of R and Coloration Index [(R-B)/R] to serve as predictors of EC (R2 >= 0.80).
The Changing Appearance of the Reading Human
Authors: Yalysheva V. V. 
Published: February 2024

Чудинова В. П. Развитие «наций читателей» в разных странах мира: исследования, стратегии, проекты, практики / В. П. Чудинова. Москва : РШБА, 2022. 360 с. (Профессиональная библиотека школьного библиотекаря) (Приложение к журналу «Школьная библиотека». Сер. 1; вып. 2).
Application of the Halal Guarantee System to Broilers in Traditional Markets: Worker’s Knowledge of Halal Guarantee
Authors: Handayani Nur Atikah , Nahariah Nahariah , Asnawi Aslina , Hikmah Hikmah 
Published: February 2024

The Indonesian government's efforts to support food and beverage products that must be halal-certified by 2024 are by implementing a halal product guarantee system in the industry. One of the industries that must implement halal guarantees is poultry slaughterhouses. One of the criteria for a halal assurance system in a poultry slaughterhouse is the role of human resources. This study aims to analyze the knowledge of human resources in Poultry Slaughterhouses. Application of knowledge about commitment and responsibility consists of halal criteria, human resource development, top management responsibilities, and training of halal staff. The object of research is poultry slaughterhouses that have implemented SNI halal standards and have not implemented SNI halal standards. The study used 52 samples using 2 technic, field studies consisting of observation, interview, questionnaire, documentation, and literature study techniques. Assessment of respondents' knowledge using the order of assessment (Likert scale). The knowledge of workers in an SNI halal standards poultry slaughterhouse regarding commitment and responsibility was in the very high category. However, poultry slaughterhouses do non-SNI halal standards have a very low category.
Keywords: poultry slaughterhouses, knowledge, halal
Robot-assisted radical cystectomy with the clinical application of "Y-shaped" end-to-side ureteral anastomosis in elderly and obese patients
Authors: Mou Yixuan , Mao Yeqing , Liu Zhenghong , Zhang Pu , Shou Jiafeng , Yang Yunkai , Qi Xiaolong , Zhang Dahong , Wo Qijun 
Published: February 2024

Abstract
Objective: To investigate the clinical effect and safety of "Y-shaped" end-to-side ureteral anastomosis with robotic endoscopic technique in radical cystectomy (RC) and urinary diversion (UD) in elderly and obese patients with bladder cancer.
Materials and methods: We retrospectively reviewed the records of 10 patients with bladder cancer who underwent robot-assisted laparoscopic radical cystectomy and "Y-shaped" end-to-side ureteral anastomosis under general anesthesia at Zhejiang Provincial People's Hospital (Affiliated People’s Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China, 310014) from October 2018 to January 2021. Demographic and clinical data are summarized. The incidence of postoperative complications such as papillary retraction, ureteral stricture, anastomotic stenosis, anastomotic fistula and ureteral calculi were observed and analyzed.
Results: A total of 10 elderly and obese patients successfully underwent RC with "Y-shaped" end-to-side ureteral anastomosis in this research. Median age was (80.6±5.7)y and BMI was (25.12±3.83) kg/m2. The operation time was (95±26) min and the estimated intraoperative blood loss was (100.5±35.6) ml, with no perioperative blood transfusion and no readmission 30 days after operation. No serious complications above Clavien-Dindo grade 4 occurred in the early (≤30 d) and late (> 30 d) after surgery. 1 patient developed fever 3 days after operation and was cured by strengthening anti-infection. 1 patient had a small amount of urine leakage at the anastomotic site after operation, and recovered after strengthening nutrition and maintaining the patency of abdominal drainage tube and single J tube. Postoperatively, the patients replaced the single J tube regularly and were followed up for 3-28 months (average 15 months) until April 10, 2021. In 2 cases, the ureterostomy nipple was slightly retracted and collapsed without special treatment. 1 case formed ureteral calculi and was treated conservatively. No ureteral stenosis, necrosis, anastomotic stenosis or severe anastomotic fistula, hernia around the stoma occurred. No visceral metastases or new lesions of urothelial carcinoma were observed. All patients were satisfied with the postoperative quality of life.
Conclusions: The robot-assisted "Y-shaped" end-to-side ureteral anastomosis technique performed intracorporeally seems to be a straightforward, secure, and viable approach. It is considered suitable for radical resection of bladder cancer and urinary diversion in elderly and obese patients.
Enhancing genomic data synthesis: A WGAN-GP approach for haplotype generation and evaluation using quasi Manhattan Wasserstein distance
Authors: Lim Evan Unit , Lim Aylwin Ming Wee , Fann Cathy SJ 
Published: February 2024

Abstract

Background
The utilization and translation of genomic data from large biobanks has revolutionized the field of biomedical research, drug development and precision medicine. Despite the advances in genetic epidemiology research, limited sample size of certain rare diseases and minority population remains a critical issue. As an alternative to collecting more samples, generating realistic synthetic human genomic data by mimicking the population structure can uplift the sample size of disease cohorts or minority groups. The recently proposed Generative Adversarial Networks (GANs) for generating artificial genomes still requires extensive hyperparameter tuning and often fails to converge.
Results
We utilized WGAN-GP on phased haplotype data sourced from individuals with type 1 diabetes (T1D: n=3,698) and a disease-free cohort (healthy: n=51,857) from the UK Biobank. Subsequently, synthetic datasets were generated, doubling the size of the original samples (TID': n=7,396, healthy': n=103,714). The input data comprised haplotype pairs with selected single nucleotide polymorphisms (SNPs), notably rs6679677 and rs2476601 in the PTPN22 gene, identified in previous genome-wide association studies (GWAS) as linked to increased T1D risk. We evaluated WGAN-GP’s ability to capture the complex multidimensional structure of the input data through Jensen–Shannon divergence, cosine distance, and a novel quasi Manhattan Wasserstein distance. Additionally, we demonstrated the two-dimensional principal component analysis (PCA) representation of real and synthetic data and showcased the allele frequencies between real and synthetic data. We introduced the Quasi Manhattan Wasserstein Distance (QMWD) and explored its potential in training.
Conclusions
The study highlights the potential of WGAN-GP in synthetic genomic data generation, addressing challenges faced by traditional GANs. QMWD, with O(n) efficiency, offers a promising avenue for improvement.
NOL10 is required for NUP98-DDX10 leukemia
Authors: Kitabayashi Issay , Shima Yutaka , Yamagata Kazutsune , Sasaki Kazuki 
Published: February 2024

Abstract
NUP98 rearrangements associated with acute myeloid leukemia and myelodysplastic syndromes generate NUP98-fusion proteins. One such fusion protein, NUP98-DDX10, contains the putative RNA helicase DDX10. The molecular mechanism by which NUP98-DDX10 induces leukemia is not well understood. Here, we show that 24 amino acids within the DDX10 moiety of NUP98-DDX10 are crucial for cell immortalization and leukemogenesis. NOL10, nucleolar protein 10, interacts with the 24 amino acids, and NOL10 is a critical dependency of NUP98-DDX10 leukemia development. Studies in a mouse model of NUP98-DDX10 leukemia showed that loss of Nol10impaired disease progression and improved survival. We also identified a novel function of NOL10 in that it acts cooperatively with NUP98-DDX10 to regulate serine biosynthesis pathways and stabilize ATF4 mRNA. Collectively, these findings suggest that NOL10 is a critical regulator of NUP98-DDX10 leukemia, and that targeting NOL10 (or the serine synthesis pathway regulated by NOL10) may be an effective therapeutic approach.
Mendelian randomization distinguished the changes in gut microbiota caused by IBD from those that lead to IBD
Authors: Li Fan , Han Xiaoping , Tang Tongyu , Wang Zhaodi , Zhao Qi , Wang Zhi , Xu Zifeng , Chang Yu , Gou Zhaoyang , Li Yuqin 
Published: February 2024

Abstract
Observational studies have reported that dysbiosis of gut microbiota may be a contributing factor in the development of IBD. However, the causal relationship between gut microbiota and IBD remains unclear due to the coexistence of gut dysbiosis in IBD patients. The aim of this study is to investigate the causal and reverse causal relationships between gut microbiota and inflammatory bowel disease (IBD).We aimed to explore the causal and reverse causal relationships between gut microbiota and IBD using a two-sample Mendelian randomization (MR) approach. Specifically, genetic variants associated with IBD were selected from the International IBD Genetics Consortium (IIBDGC) trans-ancestry genome-wide association studies (GWAS), while data related to gut microbiota were obtained from the International MiBioGen consortium. We employed various MR methods, including inverse variance-weighted (IVW), MR-Egger regression, weighted median, weighted mode, and MR-RAPS. Sensitivity analyses using MR-Egger intercept test, Cochran's Q test, and leave-one-out test were conducted for quality control.As results, Bifidobacteriaceae, Bifidobacterium, Lactobacillaceae, Lachnospiraceae UCG008 and Paraprevotella reduce the risk of CD. Family XIII AD3011 reduces the risk of CD and UC. Clostridiales vadin BB60 group reduces the risk of UC. Lachnospiraceae UCG010 genus, Oxalobacteraceae, Oxalobacter and Intestinimonas promotes CD development. Paraprevotella, Eubacterium ruminantium and Prevotellaceae genus promotes UC development. Eubacterium coprostanoligenes, Ruminococcaceae UCG005 genus promotes CD and UC development.Based on Cochran's Q test and MR-Egger intercept, there is no evidence of potential heterogeneity or pleiotropy bias in our findings. In conclusion, this study suggests that the use of novel probiotics for adjunctive therapy in IBD may present a new avenue for future IBD treatment.
Assessing the efficiency of sustainable agricultural development from the perspective of agricultural production-government poverty reduction-rainfall interactions：evidence from China
Authors: Wang Jianlin , You Zhanglan , Song Pengfei , Fang Zhong 
Published: February 2024

Abstract
The quest to eradicate poverty, central to the United Nations Sustainable Development Goals (SDGs), poses a significant global challenge. Advancement in sustainable rural development is critical to this effort, requiring the seamless integration of environmental, economic, and governmental elements. Previous research often omits the complex interactions among these factors. Addressing this gap, this study evaluates sustainable rural development in China by examining the interconnection between agricultural production and government-led poverty reduction, with annual rainfall considered an influential factor of climate change impacts on these sectors and overall sustainability. Utilizing a Meta-frontier entropy network dynamic Directional Distance Function (DDF) within an exogenous Data Envelopment Analysis (DEA) model, we categorize China's 27 provinces into southern and northern regions according to the Qinling-Huaihe line for a comparative study of environmental, economic, and governmental efficiency. This innovative approach overcomes the limitations of previous static analyses. The findings reveal: (1) Rainfall, as an exogenous variable, significantly affects agricultural production efficiency. (2) The overall efficiency in both southern and northern regions increases when accounting for rainfall. (3) Government effectiveness in poverty reduction is comparatively lower in the northern region than in the southern region when rainfall is considered. These insights underscore the importance of including climatic variables in sustainable development policies and emphasize the need for region-specific strategies to bolster resilience against climatic challenges.
Energy Efficient Cluster-Based Routing Protocol for WSN using Multi-Strategy Fusion Snake Optimizer and Minimum Spanning Tree
Authors: Yang Le , Zhang Damin , Li Lun , He Qing 
Published: February 2024

Abstract

In recent years, the widespread adoption of wireless sensor networks (WSN) has resulted in the growing integration of the Internet of Things (IoT). However, WSN encounters limitations related to energy and sensor node lifespan, making the development of an efficient routing protocol a critical concern. Cluster technology offers a promising solution to this challenge. This study introduces a novel cluster routing protocol for WSN. The system selects cluster heads and relay nodes utilizing the Multi-Strategy Fusion Snake Optimizer (MSSO) and employs the Minimum Spanning Tree algorithm for inter-cluster routing planning, thereby extending the system’s lifecycle and conserving network energy. In pursuit of an optimal clustering scheme, the paper also introduces tactics involving dynamic parameter updating, adaptive alpha mutation, and bi-directional search optimization within MSSO. These techniques significantly increase the algorithm convergence speed and expand the available search space.Furthermore, a novel efficient clustering routing model for WSN is presented. The model generates different objective functions for selecting cluster heads and relay nodes, considering factors such as location, energy, base station distance, intra-cluster compactness, inter-cluster separation, and other relevant criteria. When selecting cluster heads, the fuzzy C-means algorithm is integrated into MSSO to improve the optimization performance of the algorithm. When planning inter-cluster routing, the next hop node is selected for the relay node based on distance, residual energy, and direction.The experimental results demonstrate that the proposed protocol reduces energy consumption by at least 26.64% compared to other cluster routing protocols including LEACH, ESO, EEWC, GWO, and EECHS-ISSADE. Additionally, it increases the network lifetime of WSN by at least 25.84%, extends the stable period by at least 52.43%, and boosts the network throughput by at least 40.99%.
Outcomes of an innovative Sub-SMAS thread lifting for correction of mid-cheek groove
Authors: Huang Li-Wen , Dong Yun-Qing , Yang Yu , Li Shang-Yi , Yang Ching-Sheng , Hsu Hsin-Chien , Chang Kuang-Cheng 
Published: February 2024

Abstract

Background
The mid-cheek groove appearance is a common deficiency of the midface. This study described a novel deep plane thread lifting via the superficial muscular aponeurotic system (sub-SMAS) spaces incorporating with knit-circuit technique.
Methods
A total of 156 procedures were performed on 78 patients (5 men and 73 women, mean age of 43.21 ± 8.22 years old) in the study. Patients respectively underwent two rejuvenation procedures: (a) sub-SMAS plane thread lift and (b) supra-SMAS plane thread lift. Patients were followed up to 6 months. Clinical outcomes were evaluated using GAIS scores. Safety assessment was conducted for both types of thread –lifting procedures. Photographs were taken preoperatively and postoperatively for additional objective comparisons
Results
The patients of sub-SMAS group exhibited greater degree of improvement compare with that of supra-SMAS groups. The differences in GAIS score among groups significantly increased over time. Sub-SMAS group showed a lower GAIS score 6 months post-procedure than supra-SMAS (p < 0.01). Sub-SMAS was shown to have a longer lasting visible effect than supra-SMAS.
Conclusions
This deep plane thread lifting via the sub-SMAS spaces incorporating with knit-circuit technique is a safe procedure for correcting mid-cheek groove with favorable longevity.
Experiences and perceptions of conditional cash incentive provision and cessation among people with HIV for care engagement: A qualitative study
Authors: Giordano Julia , Lewis-Kulzer Jayne , Montoya Lina , Akama Eliud , Adhiambo Harriet Fridah , Nyadieka Everlyne , Iguna Sarah , Bukusi Elizabeth A. , Odeny Thomas , Camlin Carol S. , Thirumurthy Harsha , Petersen Maya , Geng Elvin H. 
Published: February 2024

Abstract
Background
Consistent engagement in HIV treatment is needed for healthy outcomes, yet substantial loss-to-follow up persists, leading to increased morbidity, mortality and onward transmission risk. Although conditional cash transfers (CCTs) address structural barriers, recent findings suggest that incentive effects are time-limited, with cessation resulting in HIV care engagement deterioration. We explored incentive experiences, perceptions, and effects after cessation to investigate potential mechanisms of this observation.
Methods
This qualitative study was nested within a larger trial, AdaPT-R (NCT02338739), focused on HIV care engagement in western Kenya. A subset of participants were purposively sampled from AdaPT-R participants: adults with HIV who had recently started ART, received CCTs for one year, completed one year of follow-up without missing a clinic visit, and were randomized to either continue or discontinue CCTs for one more year of follow-up. In-depth interviews were conducted by an experienced qualitative researcher using a semi-structed guide within a month of randomization. Interviews were conducted in the participants’ preferred language (Dholuo, Kiswahili, English). Data on patient characteristics, randomization dates, and clinic visit dates to determine care lapses were extracted from the AdaPT-R database. A codebook was developed deductively based on the guide and inductively refined based on initial transcripts. Transcripts were coded using Dedoose software, and thematic saturation was identified.
Results
Of 38 participants, 15 (39%) continued receiving incentives, while 23 (61%) were discontinued from receiving incentives. Half were female (N = 19), median age was 30 years (range: 19–48), and about three-quarters were married or living with partners. Both groups expressed high intrinsic motivation to engage in care, prioritized clinic attendance regardless of CCTs and felt the incentives expanded their decision-making options. Despite high motivation, some participants reported that cessation of the CCTs affected their ability to access care, especially those with constrained financial situations. Participants also expressed concerns that incentives might foster dependency.
Conclusions
This study helps us better understand the durability of financial incentives for HIV care engagement, including when incentives end. Together with the quantitative findings in the parent AdaPT-R study, these results support the idea that careful consideration be exercised when implementing incentives for sustainable engagement effects.