bluuebunny/crossref_metadata_2025_split huggingface dataset:
Amanah Orang Tua Terhadap Perkembangan dan Pendidikan Anak Prenatal Dalam Perspektif Islam
Authors: Adhy Agung Wahyu , Tamam Abas Mansur , Rahman Imas Kania 
Published: November 2023

AbstrakPendidikan anak adalah amanah yang Allah bebankan kepada para orang tua. Mereka adalah madrasah ula bagi anak-anak sebelum mereka mengenal sekolah formal. Pendidikan orang tua terhadap anak adalah amanah surat al-Tahrim ayat 6. Islam sangat memperhatikan pendidikan anak karena mereka akan menjadi Sumber Daya Manusia yang akan mempengaruhi perkembangan peradaban. Perhatian Islam terhadap pendidikan anak yang menjadi amanah bagi orang tuanya, dimulai jauh sebelum anak tersebut lahir ke dunia, yang dikenal dengan istilah pendidikan prenatal atau pra lahir. Sebelum terjadinya pembuahan (prakonsepsi), anak harus sudah mendapatkan hak yang disebut fase persiapan mendidik, di antaranya haknya adalah dipilihkan untuknya calon ayah atau ibu yang baik. Pendidikan kemudian berlanjut pascakonsepsi sampai anak dilahirkan. Pada fase ini peran orang tua sangat besar sekali. Orang tua pada masa pendidikan preanatal bisa memulainya dengan memberikan stimulus-stimulus yang dapat merangsang otak dan perkembangan syaraf sebelum lahir. Sayangnya pendidikan prenatal yang merupakan masa kritis bagi perkembangan fisik, emosi dan mental bayi masih jarang dilakukan oleh orang tua, padahal ini adalah bagian dari amanah orang tua terhadap anak-anaknya. Penyebabnya bisa karena kurangnya pengetahuan dan pengalaman, serta adanya anggapan keliru bahwa pendidikan anak baru dimulai ketika anak telah lahir yaitu pada masa preschool. Kata kunci: Amanah, Pendidikan, Prenatal AbstractChildren's education is a mandate that Allah burdens parents with. They are ula madrasas for children before they know formal schooling. Parental education for children is the mandate of Surat al-Tahrim verse 6. Islam pays great attention to children's education because they will become human resources who will influence the development of civilization. Islam's concern for children's education, which is a mandate for their parents, begins long before the child is born into the world, which is known as prenatal or prenatal education. Prior to conception (preconception), the child must have obtained the right which is called the educational preparation phase, one of which is the right to choose a good father or mother for him. Education then continues postconception until the child is born. In this phase the role of parents is very big. Parents during the prenatal education period can start by providing stimuli that can stimulate the brain and nerve development before birth. Unfortunately prenatal education which is a critical period for the physical, emotional and mental development of babies is still rarely carried out by parents, even though this is part of the mandate of parents towards their children. The reason could be due to a lack of knowledge and experience, as well as the mistaken assumption that a child's education begins only when the child is born, namely during the preschool period.Keywords: Mandate, Education, Prenatal
Edukasi Pengendalian dan Pencegahan Infeksi COVID-19 dan Pembagian Masker
Authors: Mahyarudin Mahyarudin , Wicaksono Arif , Novianry Virhan 
Published: November 2023

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a new strain of virus from the coronavirus that can cause mild disorders of the respiratory system, severe lung infections and death. This virus can attack all ages. The disease is called Coronavirus Disease (20) 19 or COVID-19. The transmission of this virus is via droplets spread by coughing or sneezing on an infected person. We cannot know someone has COVID-19 or not, so we have to adopt a clean and healthy lifestyle, and try to protect ourselves using personal protective equipment, one of which is the use of masks. The use of masks can prevent transmission of COVID-19. The purpose of this activity is to educate the public on the importance of using masks. The target of this activity is the people in Pontianak City. The expected output is that the community understands more about the disease and how it is transmitted, so that they will be more disciplined in using masks.
Keywords: SARS-CoV-2, Infection Disease Prevention, Mask
Peningkatan Produksi Perikanan Budidaya Dengan Penerapan Sistem Mina Padi Di Desa Sungai Besar Kecamatan Bunut Hulu, Kabupaten Kapuas Hulu
Authors: Shilman M. Idham , Tarno Slamet , Setiawan Agus , Nasir Muhammad , Hutagalung Rizal Akbar 
Published: November 2023

Sungai Besar Village is one of the areas in Bunut Hulu Subdistrict, Kapuas Hulu Regency, West Kalimantan, which has considerable development potential in the fisheries sector. This is reinforced by the majority of people who have a livelihood as farmers and fish farmers. In addition, Sungai Besar Village is also one of the leading regions for the fisheries sector, especially tilapia and catfish. However, the rapid increase in population can cause limited production areas that can be used in various fields of fisheries. This encourages the intensification of efforts as one way of land utilization. One way that can be done is the application of the Minapadi fish culture system. This minapadi system has several advantages including an increase in community income through the existence of fish farming and more effective land use. The development of the fisheries sector, primarily the tilapia (Oreochromis niloticus) aquaculture business using the Minapadi system, is a solution in addressing land use issues and improving the economic community in the Kapuas Hulu Regency. In addition, Sungai Besar Village is expected to become a target village for the production of fish cultivation using the Minapadi system. The method that will be used in community service activities (PPM) is the method of assisting the transformation of science and application programs (training and counseling) related to the application of fish cultivation with the Minapadi system. Expected output in this activity is the community of Sungai Besar Village is able to implement fish farming with the Minapadi system. This is in the form of a method of fish cultivation that is able to maximize land use.
Keywords : Aquaculture, Tilapia, Mina Padi, Sungau Besar Village
Pemberdayaan Kelompok Masyarakat Pesisir sebagai Mitra Penyedia Bahan Baku Udang Kupas di Desa Dabong Kecamatan Kubu Kabupaten Kubu Raya
Authors: Nofreeana Andri , Lasmi Leni , Sasongko Lukas Wibowo 
Published: November 2023

Berdasarkan potensi sumberdaya perikanan, terutama udang di Desa Dabung Kecamatan Kubu Kabupaten Kubu dan permintaan pasar ekspor terhadap udang beku, mendorong untuk membina kelompok masyarakat pesisir di Desa Dabung Kecamatan Kubu Kabupaten Kubu Raya. Luaran yang dihasilkan: (1) terbentuk kelompok masyarakat pesisir yang dapat mengolah udang kupas dengan kualitas mutu yang bagus, (2) artikel mengenai kegiatan Pengabdian Pada Masyarakat di Desa Dabong Kecamatan Kubu Kabupaten Kubu Raya dengan materi penerapan sanitasi dan higiene dalam pengolahan udang, diterbitkan di media massa Pontianak Post. Berdasarkan data yang didapat menunjukkan bahwa, hampir semua peserta menyatakan:(1) suka, setelah mengikuti kegiatan terhadap penyelenggaraan pelatihan ini, (2) sudah menguasai materi yang disampaikan mengenai penanganan dan pengupasan udang yang sesuai dengan sanitasi dan hygiene, (3) materi yang disampaikan merupakan pengetahuan baru, (4) tertarik membuka usaha penanganan dan pengupasan udang, (5) perlu dilaksanakan pelatihan selanjutnya selain penanganan dan pengupasan udang.
Peningkatan Keberlangsungan Perikanan Lokal dengan Restocking Ikan Jelawat (Leptobarbus Hoevenii) di Danau Keliling Desa Tembang Kabupaten Kapuas Hulu
Authors: Hasrah Hasrah , Tarno Slamet , Shilman M. Idham , Setiawan Agus , Juanda Eki , Nofembrianti Nofembrianti , Kurniawan Alfani , Nasir Muhammad , Muhammad Abah 
Published: November 2023

Ikan jelawat (Leptobarbus hoevenii) termasuk salah satu komoditas ekonomis penting di daerah Kalimantan Barat. Untuk menjaga ketersediaan ikan jelawat di alam dapat dilakukan dengan kegiatan pengelolaan sehingga potensi penurunan populasi ikan jelawat di alam dapat diimbangi. Saat ini, kegiatan budiaya ikan jelawat masih sedikit sementara kegiatan penangkapan yang tidak terkendali berdampak pada pengurangan populasi ikan jelawat di alam. Oleh sebab itu, perlu dilakukan pengelolaan sumberdaya perikanan melalui kegiatan restocking. Restocking adalah salah satu upaya penambahan stok ikan tangkapan untuk ditebarkan di peraian umum. Tujuan dari restocking ikan jelawat selain menambah stok ikan agar dapat dipanen dengan alat tangkap yang ramah lingkungan, juga bertujuan mengembalikan peran dan fungsi perairan umum yang seimbang. Metode pelaksanaan yang digunakan dalam kegiatan Pengabdian Pada Masyarakat (PPM) dilakukan dalam beberapa tahap yakni tahap penyediaan benih ikan, tahap penyuluhan, tahap pelaksanaan restocking dan tahap pendampingan.. Indikator keberhasilan dari kegiatan PPM yang telah dilaksanakan yaitu dengan melakukan pemantauan kegiatan PPM melalui keberlangsungan penerapan sistem kearifan lokal dan aturan daerah Danau Lindung Keliling Desa Tembang Kecamatan Bunut Hulu Kabupaten Kapuas Hulu yang telah disepakati oleh nelayan sekitar. Luaran yang dihasilkan dari kegiatan PPM yang telah dilaksanakan adalah publikasi media massa elektronik nasional dan promosi Prodi Teknologi Budidaya Perikanan Jurusan Perikanan dan Ilmu Kelautan PDD Politeknik Negeri Pontianak di Kabupaten Kapuas Hulu; mampu menghasilkan kekayaan intlektual dengan tercapainya perlindungan spesies-spesies ikan lokal khususnya ikan jelawat (Leptobarbus hoevenii) di Danau Lindung Keliling Desa Tembang Kecamatan Bunut Hulu Kabupaten Kapuas Hulu; Mitra non-produktif ekonomi dengan capaiannya peningkatan pengetahuan sumberdaya alam lokal dan sistem danau lindung konservasi.
PENEGAKAN HUKUM TERHADAP KENDARAAN YANG MELEBIHI DAYA ANGKUT DAN DIMENSI SEBAGAI UPAYA PENANGGULANGAN KECELAKAAN LALULINTAS DAN KERUSAKAN JALAN
Authors: Putra Debby Maide 
Published: November 2023

Pasal 169 ayat (1) Undang-Undang Nomor 22 Tahun 2009 Tentang Lalu Lintas dan Angkutan Jalan (LLAJ) mengatur mengenai tata cara pemuatan, daya angkut, dimensi, dan kelas jalan. Pendekatan yang digunakan adalah pendekatan Yuridis Normatif yang didukung pendekatan Yuridis Empiris. Penegakan hukum terhadap kendaraan yang melebihi daya angkut dan melebihi dimensi oleh Direktorat Lalulintas Polda Sumbar berdasarkan teori efektivitas penegakan hukum maka analisis penerapan peraturan perundang-undangan tentang pelanggaran lalu lintas dan angkutan jalan yang mengatur ketentuan muatan angkutan barang meliputi kesadaran hukum masyarakat dan budaya hukum. Terdapat 5 (lima) lokasi jembatan timbang yang diteliti tentang penegakan hukum yang dilakukan terhadap kendaraan yang kelebihan muatan dan kelebihan dimensi yaitu: jembatan timbang Lubuk Selasih, Sungai Lansek, Tanjung Balit, Beringin Panti dan Air Haji. Menunjukan penegakan hukum yang dilakukan dengan sanksi berupa peringatan, penilangan dan penindakan lainnya yakni penundaan perjalanan serta dilakukan penyesuaian muatan dan normalisasi kendaraan. Kendala Dalam Penegakan Hukum Terhadap Kendaraan Yang Melebihi Daya Angkut Dan Melebihi Dimensi Oleh Direktorat Lalulintas Polda Sumbar adalah belum penindakan yang tegas terhadap pemilik kendaraan yang memodifikasi kendaraannya dengan mengubah bentuk dan ukuran bak atau kendaraannya penindakan hanya dilakukan terhadap sopir bukan pengusaha. Kurangnya koordinasi dan fungsi kontrol antara Kemenhub dengan pihak kepolisian didalam melakukan pengawasan terhadap kendaraan yang di modifikasi.
KAJIAN TENTANG KUALITAS PELAYANAN, KEPUASAN DAN CITRA PERGURUAN TINGGI
Authors: Fanggidae Paulus Yulius , Juniarto Antonius 
Published: November 2023

Klien adalah “raja” ungkapan ini menekankan bahwa klien harus diterima atau dilayani sebagai “raja” dan tentunya mengandung makna kesediaan untuk menghadirkan raja (dalam hal ini klien) dengan aspek terbaiknya. Dimensi dunia Pelayanan merupakan variabel yang perlu diperhatikan, serta pemahaman perilaku konsumsi konsumen sasaran dalam rangka menyediakan dan menyampaikan apa yang dibutuhkan konsumen. Penyedia layanan pendidikan tinggi perlu meningkatkan kualitas layanan dengan berbagai fungsi pendukung untuk menciptakan suasana (mood) yang menarik ketika melakukan “delivery service” dalam “service summit”. Kegiatan operasional lembaga pendidikan saat ini harus mampu memuaskan kebutuhan dan keinginan pelanggan (peserta didik), memberikan pelayanan sebaik-baiknya di tengah persaingan yang semakin ketat dan semakin cerdasnya konsumen yang cenderung kurang “setia” dan bersemangat. mentransfer aktivitas Anda. loyalitas kepada penyedia layanan yang sesuai dengan visi mereka. Persaingan yang semakin ketat telah memaksa banyak penyedia layanan pendidikan untuk berinvestasi dan berkembang dalam menyediakan dan memberikan layanan berkualitas dengan menggabungkan berbagai aspek seperti manusia, peralatan, penggunaan teknologi dan program lain yang memfasilitasi “proses penyampaian” layanan pendidikan sebagai satu bagian yang tidak terpisahkan. bagian dari upaya organisasi untuk menerapkan komitmen terhadap peningkatan kualitas berkelanjutan. Hal ini memerlukan dukungan sistematis untuk melakukan survei terhadap kualitas pelayanan, kepuasan dan reputasi institusi untuk memperoleh gambaran yang benar dan akurat, yang kemudian ditindaklanjuti untuk menciptakan keunggulan kompetitif yang menjadi kekuatan untuk terus tumbuh dan berkelanjutan.
Neurovascular Correlates of Cobalamin, Folate, and Homocysteine in Dementia
Authors: Tu Min-Chien , Chung Hsiao-Wen , Hsu Yen-Hsuan , Yang Jir-Jei , Wu Wen-Chau 
Published: November 2023

Background: Cobalamin (Cbl) and folate are common supplements clinicians prescribe as an adjuvant therapy for dementia patients, on the presumption of their neurotrophic and/or homocysteine (Hcy) lowering effect. However, the treatment efficacy has been found mixed and the effects of Cbl/folate/Hcy on the human brain remain to be elucidated. Objective: To explore the neurovascular correlates of Cbl/folate/Hcy in Alzheimer’s disease (AD) and subcortical ischemic vascular dementia (SIVD). Methods: Sixty-seven AD patients and 57 SIVD patients were prospectively and consecutively recruited from an outpatient clinic. Multimodal 3-Tesla magnetic resonance imaging was performed to quantitatively evaluate cerebral blood flow (CBF) and white matter integrity. The relationship between neuroimaging metrics and the serum levels of Cbl/folate/Hcy was examined by using the Kruskal-Wallis test, partial correlation analysis, and moderation analysis, at a significance level of 0.05. Results: As a whole, CBF mainly associated with Cbl/folate while white matter hyperintensities exclusively associated with Hcy. As compared with AD, SIVD exhibited more noticeable CBF correlates (spatially widespread with Cbl and focal with folate). In SIVD, a bilateral Cbl-moderated CBF coupling was found between medial prefrontal cortex and ipsilateral basal ganglia, while in the fronto-subcortical white matter tracts, elevated Hcy was associated with imaging metrics indicative of increased injury in both axon and myelin sheath. Conclusions: We identified the neurovascular correlates of previously reported neurotrophic effect of Cbl/folate and neurotoxic effect of Hcy in dementia. The correlates exhibited distinct patterns in AD and SIVD. The findings may help improving the formulation of supplemental Cbl/folate treatment for dementia.
The p110α/ΔNp63α complex mutations in triple-negative breast cancer: Potential targets for transcriptional-based therapies
Authors: Ma Wenqiong , Han Xingping , Shasaltaneh Marzieh Dehghan , Hosseinifard Hossein , Maghsoudloo Mazaher , Zhang Yuqin , Weng Qiao , Wang Qingjing , Wen QingLian , Imani Saber 
Published: November 2023

BACKGROUND: Hotspot mutations occurring in the p110α domain of the PIK3CA gene, specifically p110αH1047R/L increase tumor metastasis and cell motility in triple-negative breast cancer (TNBC). These mutations also affect the transcriptional regulation of ΔNp63α, a significant isoform of the p53 protein involved in cancer progression. This study attempts to investigate the transcriptional impact of p110αH1047R/L mutations on the PIK3CA/ΔNp63α complex in TNBC carcinogenesis. METHODS: We performed site-directed mutagenesis to introduce p110αH1047R/L mutations and evaluated their oncogenic effects on the growth, invasion, migration, and apoptosis of three different TNBC cell lines in vitro. We investigated the impact of these mutations on the p110α/ΔNp63α complex and downstream transcriptional signaling pathways at the gene and protein levels. Additionally, we used bioinformatics techniques such as molecular dynamics simulations and protein-protein docking to gain insight into the stability and structural changes induced by the p110αH1047R/L mutations in the p110α/ΔNp63α complex and downstream signaling pathway. RESULTS: The presence of PIK3CA oncogenic hotspot mutations in the p110α/ΔNp63α complex led to increased scattering of TNBC cells during growth, migration, and invasion. Our in vitro mutagenesis assay showed that the p110αH1047R/L mutations activated the PI3K- Akt- mTOR and tyrosine kinase receptor pathways, resulting in increased cell proliferation, invasion, and apoptosis in TNBC cells. These mutations decreased the repressing effect of ΔNp63α on the p110α kinase domain, leading to the enhancement of downstream signaling pathways of PI3K and tyrosine kinase receptors and oncogenic transformation in TNBC. Additionally, our findings suggest that the physical interaction between the DNA binding domain of ΔNp63α and the kinase domain of p110α may be partially impaired, potentially leading to alterations in the conformation of the p110α/ΔNp63α complex. CONCLUSION: Our findings suggest that targeting the p110αH1047R/L mutations in TNBC could be a promising strategy for developing transcriptional-based therapies. Restoring the interaction between ΔNp63α and the p110α kinase domain, which is disrupted by these mutations, may provide a new approach to treating TNBC.
Film Review: Jagun Jagun, Nigeria, 2023. Produced by Euphoria 360 Media. Netflix. 129 minutes, Yoruba (with English subtitles). No price reported. Directed by Tope Adebayo and Adebayo Tijani
Authors: Atanda Yemi 
Published: November 2023

I intend to argue in this review that the Yoruba film Jagun Jagun represents the transition of the Yoruba Travelling Theatre into the big screen motion picture. It has been a remarkable transformation from stage crafts to filmic crafts, while still retaining the “family” involvement in the vibrant business innovations of the New Nollywood. Doing this focuses on configuring the interface between technology and entrepreneurship with its attendance use of traditional visual elements, songs, dance, imageries, metaphors and other Yoruba poetic renditions for aesthetic values. However, it is noted that the inappropriate mingling of both traditional and modern visual effects influenced by the Western postmodernist style in filmic framing, composition, sound, music and war combat mode. Generally, the film occludes the postcolonial thematic relevance in the modern political African leaders in their visionless Machiavellian ideology.
Avatar legal protection as an atypical copyright object
Authors: Kroitor V. A. 
Published: November 2023

The legal protection of an avatar as an atypical copyright object has been investigated. The originality and objective form of an avatar have been established and characterised, which will allow correlating an avatar with atypical copyright objects, and the atypicality of an avatar as an object of copyright has been emphasised.
It has been determined that the phenomenon of an avatar as a legal category is that it is a complex category which has a different legal regime. It has been noted that it is most appropriate to relate an avatar to an object of rights, in particular, in the field of personal non-property rights and intellectual property rights. Creating objects with the help of a neural network, in particular, an avatar in the form of a computer copy of a person, is a complex work of different people. At the same time, this work has signs of intellectual, scientific and creative activity. Due to the complexity of such activity, it may fall under different legal regimes of intellectual property rights, in particular copyright and patent law. An avatar as a game character can be considered as an object of copyright. If an avatar is created using digital tools offered by the developers of a computer game, the copyright belongs to the respective developers.
It has been proved that an avatar is an intangible benefit that can include such virtual objects as: a game character tied to a specific user; a social network profile of a person; a computer copy of a person with unique identification features, originality and objective form. It has the following characteristics: the presence of a digital objective form that makes it possible to perceive the avatar in the digital environment, originality, uniqueness, and the availability of legal access to use the avatar. The legal protection of an avatar within the framework of copyright may be carried out under two legal regimes: copyright protection; and the institute of rights of a special kind (sui generis). It would be appropriate to supplement the Law of Ukraine “On Copyright and Related Rights” with a definition of an avatar and rights to it.
PHYTOCHEMICAL CONSTITUENTS AND INVITRO FREE RADICAL SCAVENGING ACTIVITIES OF METHANOL EXTRACT AND FRACTIONS OF Ficus platyphylla LEAVES (MORACEAE)
Authors: Shemishere Ufuoma Bigila , Turaki Aliyu Abdullahi , Yusuf Abdulrahman Bashir , Anyebe Daniel Abu , Erhovwosere Oghenevwede , Aghayere Faith , Taiwo Judith Enuwamagbe 
Published: November 2023

The demand for plant-based antioxidants is expanding rapidly due to their effectiveness and accessibility. This study examined the phytochemical constituent and in vitro free radical scavenging activities of Methanol extract and fractions of Ficus platyphylla leaves. Standard known methods were used to determine the qualitative and quantitative phytochemical constituents and free radical scavenging activities of the extract and fractions of the plant dried leaves. Methanol extraction produced a yield of 12.64%. Qualitative phytochemical screening confirmed the presence of alkaloids in the extract and all but chloroform fraction. Flavonoids and steroids were present in all except n-Butanol fraction. Saponins were detected in only methanol extract and n-Butanol fraction while terpenoids were not present in n-Hexane, chloroform and n-Butanol fractions. Anthraquinones, coumarins, quinones and xanthoproteins were not confirmed in all fractions and extract. Quantitative analyses revealed a significant difference (p < 0.05) in the contents of the total phenolics and total flavonoids in the fractions when compared to the methanol extract. The leaf extract and fraction's ability to scavenge free radicals against 1,1-diphenyl-2-picrylhydrazyl (DPPH) demonstrated a concentration-dependent percentage inhibition. However, the methanol extract, n-Butanol and ethyl acetate fractions were most effective of all the fractions. This study has demonstrated the different fractions and methanol extract of Ficus platyphylla leaves can explored in the management of oxidative stress related complications in mammals.