bluuebunny/crossref_metadata_2025_split huggingface dataset:
A preliminary investigation of rabbit carcass decomposition and attracted ants (Hymenoptera: Formicidae) on the seaward coastal beach of Al-Jubail City, Saudi Arabia
Authors: Al-Qurashi Afnan S , Mashaly Ashraf M , Alajmi Reem , Al-Khalifa Mohamed S , Mansour Lamjed , Al-Omar Suliman Y , Sharaf Mostafa R , Aldawood Abdulrahman S , Al-Dhafer Hathal M , Hunter Tony , Almutawa Masha’el Y , Ahmed Ashraf M 
Published: December 2023

Abstract
The current study was carried out in the seaward coastal beach environment of Al-Jubail City, Saudi Arabia, to analyze the rabbit carcass decomposition process, the succession pattern of associated ants, and their potential utility in forensic investigation. Experiments were conducted over a 4-season course (from autumn 2018 to summer 2019). A total of 9 species belonging to the 2 subfamilies, Myrmicinae and Formicinae, were recorded. The myrmicine species were Crematogaster aegyptiaca Mayr, 1862; Messor ebeninus Santschi, 1927; Messor foreli Santschi, 1923; and Monomorium abeillei Andre, 1881. The formicine species were Camponotus xerxes Forel, 1904; Cataglyphis albicans (Roger, 1859); Cataglyphis hologerseniCollingwood & Agosti, 1996; Cataglyphis viaticoides (André, 1881); and Nylanderia jaegerskioeldi (Mayr, 1904). M. abeillei was the only species recorded in all 4 seasons, while M. abeillei and C. albicans were the dominant species in summer and C. aegyptiaca and C. albicans in spring. Diversity was lowest in the autumn, with only 4 species recorded. The COI gene sequences of 5 species have been successfully deposited in the GenBank database for the first time. In total, 4 carcass decomposition stages were observed, with the longest duration in winter (13 days), the shortest in summer (11 days), and in between for both autumn and spring. Most ant species were present during both decay and dry stages, while M. abeillei, C. aegyptiaca, M. ebeninus, and C. albicans were observed in all decomposition stages. These data may indicate that ants on this coastal beach showed seasonal and geographical succession patterns that could be taken into consideration in forensic investigations.
Genetic trio of BRAF and TERT alterations and rs2853669TT in papillary thyroid cancer aggressiveness
Authors: Liu Rengyun , Zhu Guangwu , Tan Jie , Shen Xiaopei , Xing Mingzhao 
Published: December 2023

Abstract

Background
BRAF V600E and TERT promoter alterations are core components in current genetics-based risk assessment for precision management of papillary thyroid cancer. It remains unknown whether this approach could achieve even better precision through a widely recognized prognostic single-nucleotide variation (SNV, formerly SNP), rs2853669T&gt;C, in the TERT promoter.

Methods
The genetic status of alterations and SNV were examined by sequencing genomic DNA from papillary thyroid cancer in 608 patients (427 women and 181 men) aged 47 years (interquartile range = 37-57), with a median follow-up time of 75 months (interquartile range = 36-123), and their relationship with clinical outcomes was analyzed. A luciferase reporter assay was performed to examine TERT promoter activities.

Results
TERT promoter alterations showed a strong association with papillary thyroid cancer recurrence in the presence of genotype TT of rs2853669 (adjusted hazard ratio [HR] = 2.12, 95% confidence interval [CI] = 1.10 to 4.12) but not TC/CC (adjusted HR = 1.17, 95% CI = 0.56 to 2.41). TERT and BRAF alterations commonly coexisted and synergistically promoted papillary thyroid cancer recurrence. With this genetic duet, TT of rs2853669 showed a robustly higher disease recurrence than TC/CC (adjusted HR = 14.26, 95% CI = 2.86 to 71.25). Patients with the genetic trio of BRAF V600E, TERT alteration, and TT of rs2853669 had a recurrence of 76.5% vs recurrence of 8.4% with neither variation and with TC/CC (HR = 13.48, 95% CI = 6.44 to 28.21). T allele of rs2853669 strongly increased TERT promoter activities, particularly the variant promoters.

Conclusions
The SNV rs2853669T&gt;C dramatically refines the prognostic power of BRAF V600E and TERT promoter alterations to a higher precision, suggesting the need for including this SNV in the current genetics-based risk prognostication of papillary thyroid cancer.
Propagation effects at low frequencies seen in the LOFAR long-term monitoring of the periodically active FRB 20180916B
Authors: Gopinath A , Bassa C G , Pleunis Z , Hessels J W T , Chawla P , Keane E F , Kondratiev V , Michilli D , Nimmo K 
Published: December 2023

ABSTRACT
LOFAR (LOw Frequency ARray) has previously detected bursts from the periodically active, repeating fast radio burst (FRB) source FRB 20180916B down to unprecedentedly low radio frequencies of 110 MHz. Here, we present 11 new bursts in 223 more hours of continued monitoring of FRB 20180916B in the 110–188 MHz band with LOFAR. We place new constraints on the source’s activity window $w =4.3^{+0.7}_{-0.2}$ d and phase centre $\phi _{\mathrm{c}}^{\mathrm{LOFAR}} = 0.67^{+0.03}_{-0.02}$ in its 16.33-d activity cycle, strengthening evidence for its frequency-dependent activity cycle. Propagation effects like Faraday rotation and scattering are especially pronounced at low frequencies and constrain properties of FRB 20180916B’s local environment. We track variations in scattering and time–frequency drift rates, and find no evidence for trends in time or activity phase. Faraday rotation measure (RM) variations seen between June 2021 and August 2022 show a fractional change &gt;50 per cent with hints of flattening of the gradient of the previously reported secular trend seen at 600 MHz. The frequency-dependent window of activity at LOFAR appears stable despite the significant changes in RM, leading us to deduce that these two effects have different causes. Depolarization of and within individual bursts towards lower radio frequencies is quantified using LOFAR’s large fractional bandwidth, with some bursts showing no detectable polarization. However, the degree of depolarization seems uncorrelated to the scattering time-scales, allowing us to evaluate different depolarization models. We discuss these results in the context of models that invoke rotation, precession, or binary orbital motion to explain the periodic activity of FRB 20180916B.
JWST reveals star formation across a spiral arm in M33
Authors: Peltonen Joshua , Rosolowsky Erik , Williams Thomas G , Koch Eric W , Dolphin Andrew , Chastenet Jérémy , Dalcanton Julianne J , Ginsburg Adam , Johnson L Clifton , Leroy Adam K , Richardson Theo , Sandstrom Karin M , Sarbadhicary Sumit K , Smercina Adam , Wainer Tobin , Williams Benjamin F 
Published: December 2023

ABSTRACT
Young stellar objects (YSOs) are the gold standard for tracing star formation in galaxies but have been unobservable beyond the Milky Way and Magellanic Clouds. But that all changed when the JWST was launched, which we use to identify YSOs in the Local Group galaxy M33, marking the first time that individual YSOs have been identified at these large distances. We present Mid-Infrared Instrument (MIRI) imaging mosaics at 5.6 and 21 $\mu$m that cover a significant portion of one of M33’s spiral arms that has existing panchromatic imaging from the Hubble Space Telescope and deep Atacama Large Millimeter/submillimeter Array CO measurements. Using these MIRI and Hubble Space Telescope images, we identify point sources using the new dolphot MIRI module. We identify 793 candidate YSOs from cuts based on colour, proximity to giant molecular clouds (GMCs), and visual inspection. Similar to Milky Way GMCs, we find that higher mass GMCs contain more YSOs and YSO emission, which further show YSOs identify star formation better than most tracers that cannot capture this relationship at cloud scales. We find evidence of enhanced star formation efficiency in the southern spiral arm by comparing the YSOs to the molecular gas mass.
An outburst and FU Ori-type disc of a former low-luminosity protostar
Authors: Ashraf Mizna , Jose Jessy , Lee Ho-Gyu , Contreras Peña Carlos , Herczeg Gregory J , Liu Hanpu , Johnstone Doug , Lee Jeong-Eun 
Published: December 2023

ABSTRACT
Strong accretion outbursts on to protostars are associated with emission dominated by a viscously heated disc, which is characterized by high luminosities. We report the discovery and characterization of a strong mid-IR (3.4, 4.6 μm) outburst in the embedded protostar SSTgbs J21470601+4739394 (hereafter SSTgbsJ214706). SSTgbsJ214706 has steadily brightened in the mid-infrared by ∼2 mag over the past decade, as observed by NEOWISE. Follow-up investigations with the Gemini near-IR spectrograph reveal that SSTgbsJ214706 is a binary system with a spatially extended outflow. The outburst is occurring on the more embedded south-east (SE) component, which dominates the mid- and far-infrared emission from the source. The outbursting component exhibits a spectrum consistent with an FU Ori-type outburst, including the presence of enhanced absorption observed in the molecular bands of CO. The luminosity of the SE component is estimated to be $\sim 0.23\,$ L⊙ before the outburst and $\sim 0.95\,$ L⊙ during the outburst, which is one to two orders of magnitude fainter than bonafide FU Ori outbursts. We interpret this eruption as an FU Ori-type outburst, although the possibility of brightening following an extinction episode cannot be ruled out. We discuss the implications and potential explanations for such a low-luminosity eruption.
Bursty star formation and galaxy–galaxy interactions in low-mass galaxies 1 Gyr after the Big Bang
Authors: Asada Yoshihisa , Sawicki Marcin , Abraham Roberto , Bradač Maruša , Brammer Gabriel , Desprez Guillaume , Estrada-Carpenter Vince , Iyer Kartheik , Martis Nicholas , Matharu Jasleen , Mowla Lamiya , Muzzin Adam , Noirot Gaël , Sarrouh Ghassan T E , Strait Victoria , Willott Chris J , Harshan Anishya 
Published: December 2023

ABSTRACT
We use CANUCS JWST/NIRCam imaging of galaxies behind the gravitationally-lensing cluster MACS J0417.5-1154 to investigate star formation burstiness in low-mass (M⋆ ∼ 108 M⊙) galaxies at z ∼ 4.7–6.5. Our sample of 123 galaxies is selected using the Lyman break selection and photometric emission-line excess methods. Sixty per cent of the 123 galaxies in this sample have Hα-to-UV flux ratios that deviate significantly from the range of Hα-to-UV ratio values consistent with smooth and steady star formation histories. This large fraction indicates that the majority of low-mass galaxies is experiencing bursty star formation histories at high redshift. We also searched for interacting galaxies in our sample and found that they are remarkably common ($\sim 40~{{\ \rm per\ cent}}$ of the sample). Compared to non-interacting galaxies, interacting galaxies are more likely to have very low Hα-to-UV ratios, suggesting that galaxy–galaxy interactions enhance star formation burstiness and enable faster quenching (with time-scales of ≲100 Myr) that follows the rapid rise of star formation activity. Given the high frequency of galaxy–galaxy interactions and the rapid SFR fluctuations they appear to cause, we conclude that galaxy–galaxy interactions could be a leading cause of bursty star formation in low-mass, high-z galaxies. They could thus play a significant role in the evolution of the galaxy population at early cosmological times.
Dwarfs in nearby voids: results of SALT spectroscopy
Authors: Pustilnik S A , Kniazev A Y , Tepliakova A L , Perepelitsyna Y A , Egorova E S 
Published: December 2023

ABSTRACT
In the framework of the ongoing project, aimed at the systematical studying galaxies in nearby voids, we conducted spectroscopy with the Southern African Large Telescope (SALT) of 62 objects from the Nearby Void Galaxy (NVG) sample. They include 8 remaining objects of the 60 pre-selected candidates to eXtremely Metal-Poor (XMP) dwarfs, two known void XMP dwarfs and 52 void dwarfs residing within the Local Volume. For 47 galaxies residing in the nearby voids, we obtained spectra of the diverse quality. For 42 of them, we detected the Hydrogen and Oxygen lines that allowed us to get estimates of O/H in the observed H ii regions. For 12 of the 42 objects, we detected the faint line [O iii]λ4363, that allowed us to directly derive the electron temperature Te and obtain their gas O/H by the direct method. 14 objects with the undetected [O iii]λ4363 line fall to the lowest metallicities range (12+log(O/H) ≲ 7.5 dex). For them, we use a carefully checked new empirical ‘Strong line’ method of Izotov et al. For 14 other objects with only strong lines detected and with 12+log(O/H) of ∼7.5–8.0 dex, we used the modified version of ‘semi-empirical’ method of Izotov and Thuan. It accounts for effect of the excitation parameter O32 on Te. 16 new galaxies are found with parameter 12+log(O/H) ≲ 7.39 dex. Of them, four have 12+log(O/H) = 7.07–7.20 dex. Of the 60 observed NVG objects, 15 have mistaken radial velocities in HyperLEDA. They do not reside in the nearby voids.
A strontium-rich ultra-metal-poor star in the Atari disc component
Authors: Mardini Mohammad K , Frebel Anna , Chiti Anirudh 
Published: December 2023

ABSTRACT
We report on the discovery of the first ultra-metal-poor (UMP) star 2MASS J20500194−6613298 (J2050−6613; [Fe/H] = −4.05) selected from the Gaia BP/RP spectral catalogue that belongs to the ancient Atari disc component. We obtained a high-resolution spectrum for the star with the MIKE spectrograph on the Magellan-Clay telescope. J2050−6613 displays a typical chemical abundance pattern for UMP stars, including carbon and zinc enhancements. In contrast, J2050−6613 shows extremely high [Sr/Fe] and [Sr/Ba] ratios compared to other stars in the [Fe/H] &lt; −4.0 regime. J2050−6613 is most likely an early Population II star that formed from a gas cloud that was chemically enriched by a massive Population III hypernova (E &gt; 1052 erg). Such a Population III core-collapse hypernova could simultaneously explain the origin of the abundance pattern of light and heavy elements of 2MASS J2050−6613 if a large amount of Sr of ∼10−5 M⊙ was produced, possibly by neutrino-driven (wind) ejecta. Therefore, the abundance pattern of 2MASS J2050−6613 places important constraints on Sr-producing nucleosynthesis sources operating in the Atari progenitor at the earliest times.
Endometrial stromal cell autophagy-dependent ferroptosis caused by iron overload in ovarian endometriosis is inhibited by the ATF4-xCT pathway
Authors: Dong Xiaoyu , Xu Le , Wang Shuang , Jiao Xue , Yan Shumin , Huang Yufei , Yuan Ming , Wang Guoyun 
Published: December 2023

Abstract
Ferroptosis is an iron-dependent programmed cell death process characterized by the accumulation of lethal oxidative damage. Localized iron overload is a unique clinical phenomenon in ovarian endometriosis (EM). However, the role and mechanism of ferroptosis in the course of ovarian EM remain unclear. Traditionally, autophagy promotes cell survival. However, a growing body of research suggests that autophagy promotes ferroptosis under certain conditions. This study aimed to clarify the status of ferroptosis in ovarian EM and explore the mechanism(s) by which iron overload causes ferroptosis and ectopic endometrial resistance to ferroptosis in human. The results showed increased levels of iron and reactive oxygen species in ectopic endometrial stromal cells (ESCs). Some ferroptosis and autophagy proteins in the ectopic tissues differed from those in the eutopic endometrium. In vitro, iron overload caused decreased cellular activity, increased lipid peroxidation levels, and mitochondrial morphological changes, whereas ferroptosis inhibitors alleviated these phenomena, illustrating activated ferroptosis. Iron overload increased autophagy, and ferroptosis caused by iron overload was inhibited by autophagy inhibitors, indicating that ferroptosis caused by iron overload was autophagy-dependent. We also confirmed the effect of iron overload and autophagy on lesion growth in vivo by constructing a mouse EM model; the results were consistent with those of the in vitro experiments of human tissue and endometrial stomal cells. However, ectopic lesions in patients can resist ferroptosis caused by iron overload, which can promote cystine/glutamate transporter hyperexpression by highly expressing activating transcription factor 4 (ATF4). In summary, local iron overload in ovarian EM can activate autophagy-related ferroptosis in ESCs, and ectopic lesions grow in a high-iron environment via ATF4-xCT while resisting ferroptosis. The effects of iron overload on other cells in the EM environment require further study. This study deepens our understanding of the role of ferroptosis in ovarian EM.
Ames test study designs for nitrosamine mutagenicity testing: qualitative and quantitative analysis of key assay parameters
Authors: Thomas Dean N , Wills John W , Tracey Helen , Baldwin Sandy J , Burman Mark , Williams Abbie N , Harte Danielle S G , Buckley Ruby A , Lynch Anthony M 
Published: December 2023

Abstract
The robust control of genotoxic N-nitrosamine (NA) impurities is an important safety consideration for the pharmaceutical industry, especially considering recent drug product withdrawals. NAs belong to the ‘cohort of concern’ list of genotoxic impurities (ICH M7) because of the mutagenic and carcinogenic potency of this chemical class. In addition, regulatory concerns exist regarding the capacity of the Ames test to predict the carcinogenic potential of NAs because of historically discordant results. The reasons postulated to explain these discordant data generally point to aspects of Ames test study design. These include vehicle solvent choice, liver S9 species, bacterial strain, compound concentration, and use of pre-incubation versus plate incorporation methods. Many of these concerns have their roots in historical data generated prior to the harmonization of Ames test guidelines. Therefore, we investigated various Ames test assay parameters and used qualitative analysis and quantitative benchmark dose modelling to identify which combinations provided the most sensitive conditions in terms of mutagenic potency. Two alkyl-nitrosamines, N-nitrosodimethylamine (NDMA) and N-nitrosodiethylamine (NDEA) were studied. NDMA and NDEA mutagenicity was readily detected in the Ames test and key assay parameters were identified that contributed to assay sensitivity rankings. The pre-incubation method (30-min incubation), appropriate vehicle (water or methanol), and hamster-induced liver S9, alongside Salmonella typhimurium strains TA100 and TA1535 and Escherichia coli strain WP2uvrA(pKM101) provide the most sensitive combination of assay parameters in terms of NDMA and NDEA mutagenic potency in the Ames test. Using these parameters and further quantitative benchmark dose modelling, we show that N-nitrosomethylethylamine (NMEA) is positive in Ames test and therefore should no longer be considered a historically discordant NA. The results presented herein define a sensitive Ames test design that can be deployed for the assessment of NAs to support robust impurity qualifications.
GPATCH4 regulates rRNA and snRNA 2′-O-methylation in both DHX15-dependent and DHX15-independent manners
Authors: Kanwal Nidhi , Krogh Nicolai , Memet Indira , Lemus-Diaz Nicolas , Thomé Chairini C , Welp Luisa M , Mizi Athanasia , Hackert Philipp , Papantonis Argyris , Urlaub Henning , Nielsen Henrik , Bohnsack Katherine E , Bohnsack Markus T 
Published: December 2023

Abstract
Regulation of RNA helicase activity, often accomplished by protein cofactors, is essential to ensure target specificity within the complex cellular environment. The largest family of RNA helicase cofactors are the G-patch proteins, but the cognate RNA helicases and cellular functions of numerous human G-patch proteins remain elusive. Here, we discover that GPATCH4 is a stimulatory cofactor of DHX15 that interacts with the DEAH box helicase in the nucleolus via residues in its G-patch domain. We reveal that GPATCH4 associates with pre-ribosomal particles, and crosslinks to the transcribed ribosomal DNA locus and precursor ribosomal RNAs as well as binding to small nucleolar- and small Cajal body-associated RNAs that guide rRNA and snRNA modifications. Loss of GPATCH4 impairs 2′-O-methylation at various rRNA and snRNA sites leading to decreased protein synthesis and cell growth. We demonstrate that the regulation of 2′-O-methylation by GPATCH4 is both dependent on, and independent of, its interaction with DHX15. Intriguingly, the ATPase activity of DHX15 is necessary for efficient methylation of DHX15-dependent sites, suggesting a function of DHX15 in regulating snoRNA-guided 2′-O-methylation of rRNA that requires activation by GPATCH4. Overall, our findings extend knowledge on RNA helicase regulation by G-patch proteins and also provide important new insights into the mechanisms regulating installation of rRNA and snRNA modifications, which are essential for ribosome function and pre-mRNA splicing.
Tracing the Land in Dependency and World-Systems Theories
Authors: Ajl Max 
Published: December 2023

Abstract
This chapter surveys central theories of underdevelopment—namely, the dependency, neocolonial, and world-systems schools. These ways of thinking, emerging from the national liberation and antisystemic struggles of the Third World, were central intellectual and political challenges to capitalist modernization and imperialism. They anatomized the structure of the world-system and dissected contemporary imperialist dynamics, in the process exploding the myths of modernization theory and orthodox Eurocentric Marxisms alike. The chapter first puts forward some central theorists and problematics, then surveys “anti-dependency” thinking from the periphery, in particular that focused on how to rupture from underdevelopment and neo-colonialism. It highlights thinkers focused on auto-centered development and delinking, including their technological components.
Facial Recognition in Law Enforcement
Authors: Hälterlein Jens 
Published: December 2023

Abstract
This chapter discusses the use of facial recognition technology (FRT) by law enforcement with a special focus on machine learning applications. First, FRT is situated in the larger context of the rise of video surveillance and a shift in Western security culture. The chapter shows how the promise of FRT addresses the problems of video surveillance. Then, it explains how FRT works and how machine learning techniques such as eigenface and convolutional neural networks come into play. Afterward, it explains how the accuracy and effectiveness of FRT are evaluated and why it is important to take the interplay of human operators and FRT systems into account. Finally, several controversies around the police use of FRT are presented and the limits of technological solutions to the problem of bias are demonstrated.
The Use and Promises of Machine Learning in Financial Markets
Authors: Spears Taylor , Bondo Hansen Kristian 
Published: December 2023

Abstract
This chapter examines the use of machine learning (ML) in financial markets and argues that the adoption of ML into finance is bringing to light new issues that have traditionally fallen outside the purview of the sociology of finance and financial modeling. Furthermore, the chapter argues that the use of ML methods may be facilitating a cultural and infrastructural alignment between big tech and financial services through both the adoption of open source software within finance and the dependence of ML on large-scale cloud infrastructures. Accordingly, the chapter identifies two potential directions for future work on the sociology of financial machine learning: a “horizontal” expansion to account for the ways machine learning is being used across financial institutions, and a “vertical” deepening that investigates the infrastructures upon which ML systems are developed and deployed, and how they are shaping financial institutions and markets.