bluuebunny/crossref_metadata_2025_split huggingface dataset:
Surgical treatment of pelvic lipomatosis: a systematic review of 231 cases
Authors: Xia Mancheng , Xiong Shengwei , Li Zhihua , Fan Shubo , Chen Yuke , Zhou Liqun , Zhang Kai , Li Xuesong 
Published: December 2023

Background: Pelvic lipomatosis (PL) is a rare condition that is characterized by excessive growth of fat in the pelvic cavity. Studies have yet to systematically review surgical treatments for PL. Objectives: To provide a reference for selecting reasonable surgical treatments for PL patients according to previous literature on the surgical treatment of PL. Design and methods: We conducted this systematic review in accordance with the Preferred Reporting Items for a Systematic Review and Meta-Analysis (PRISMA) of Individual Participant Data guidelines. Literature on PL published from 1968 to 2022 was retrieved from the PubMed and EMBASE databases. Data were collected and analyzed independently by two independent investigators. Results: A total of 42 studies, involving 231 patients with PL, were included in the analysis. The surgical treatments included transurethral resection (TUR) (48.5%), ureteral stent placement (11.7%), percutaneous nephrostomy (1.3%), ureterocutaneostomy (1.3%), ureteral reimplantation (10.4%), ileal conduit (13%), and allograft kidney transplantation (0.4%). After excluding patients with unclear prognoses, 42.9% of patients showed improvement in lower urinary tract symptoms (LUTS) after TUR. Ureteral stent placement provided relief of hydronephrosis in 62.5% of PL patients. Percutaneous nephrostomy resulted in stable renal function in 33.3% of PL patients, while ureterocutaneostomy led to remission of postoperative hydronephrosis in 33.3% of PL patients. After ureteral reimplantation, 70.8% of patients experienced relief of hydronephrosis or had stable renal function. Ileal conduit led to remission of hydronephrosis, alleviation of symptoms, or maintenance of stable renal function in 83.3% of PL patients. One patient with PL had stable renal function after allograft renal transplantation. Conclusion: The surgical treatments for PL include TUR, ureteral stent placement, urinary diversion, and allograft renal transplantation. However, the choice of surgical method should be determined after comprehensive consideration of the patient’s condition.
Respiratory morbidity in Schistosoma mansoni infection: a rapid review of literature
Authors: Baluku Joseph Baruch , Olum Ronald , Sanya Richard E. , Ocama Ponsiano 
Published: December 2023

Background: Schistosomiasis contributes to 2.5 million disability-adjusted life years globally. Acute and chronic respiratory morbidity of Schistosoma mansoni ( S. mansoni) is poorly documented in the literature. We conducted a rapid literature review of the burden of respiratory symptoms and lung function abnormalities among patients with S. mansoni. We also report the immunologic and lung imaging findings from the studies reviewed. Methods: We carried out a comprehensive literature search in Embase and MEDLINE from the inception of the databases to 13th March 2023. Results: A total of 2243 patients with S. mansoni were reported from 24 case reports, 11 cross-sectional studies, 7 case series, 2 cohort studies and 2 randomized controlled trials. The prevalence of any respiratory symptom was 13.3–63.3% (total number of patients studied, n = 149). The prevalence of the individual symptoms among patients with S. mansoni in whom respiratory symptoms were sought for was as follows: cough (8.3–80.6%, n = 338), dyspnea (1.7–100.0%, n = 200), chest pain (9.0–57.1%, n = 86), sputum production (20.0–23.3%, n = 30) and wheezing (0.0 – 20.0%, n = 1396). The frequency of the symptoms tended to be higher in acute schistosomiasis. Restrictive lung disease was prevalent in 29.0% (9/31). The commonest chest imaging findings reported were nodules (20–90%, n = 103) and interstitial infiltrates (12.5–23.0%, n = 89). Peripheral blood eosinophilia was prevalent in 72.0–100.0% of patients ( n = 130) with acute schistosomiasis and correlated with symptoms and imaging abnormalities. Three case reports in chronic S. mansoni reported elevated C-reactive protein, leucocyte, neutrophil and absolute eosinophil counts, eosinophil percentage, IgE and IgG4. Conclusion: There is a high prevalence of respiratory morbidity among patients with S. mansoni, particularly in the acute stage of the infection, although the studies are relatively small. Larger studies are needed to characterize respiratory morbidity in chronic schistosomiasis and determine the underlying clinical and immunological mechanisms.
Positive psychology interventions for family caregivers coping with cancer: Who will use them?
Authors: F Hoodin , V Gupta , A Mazzoli , T Braun , SW Choi 
Published: December 2023

Background Positive psychology-based (PPB) activities have been under-researched in cancer caregiving. Objective This study investigated caregiver: (1) attitudes toward using PPB activities while caregiving; and (2) characteristics associated with these attitudes. Methods Secondary analyses of a cross-sectional survey were conducted in a national caregiver sample of hematopoietic cell transplant (HCT) patients. Survey items assessed caregivers’ likelihood of engaging in six PPB activities. Hierarchical regression was performed and potential predictors of PPB activity use (e.g., technology familiarity, coping style, caregiving duration) were examined. Results Most of the N = 948 respondents were White (78.9%), female (65.5%), married (86.7%), employed (78.4%), and college-educated (79.8%). Caregivers favorably disposed to positive activities were younger and female, provided care for 6–12 months and >40 h/week, and used coping styles involving religion and social support. Conclusions Our findings provide guidance for development and testing of PPB activities for cancer caregivers.
Effects on the Lower Limb Anthropometry in Patients with Unilateral Idiopathic Clubfoot Treated Conservatively with Ponseti Technique
Authors: Dua Mohit 
Published: December 2023

Category: Other; Basic Sciences/Biologics Introduction/Purpose: Congenital Talipes Equino-Varus is amongst the most common congenital orthopaedic anomalies. Limb length discrepancy is considered as the commonest complication in patients with unilateral clubfoot despite the best non- operative correction. In the present series of cases we aim to study all the possible effects on the lower limb anthropometry in patients with unilateral idiopathic clubfoot who have been managed conservatively. Methods: This retrospective study included 47 patients with idiopathic, unilateral CTEV who were successfully treated with Ponseti’s technique. Patients with neuromuscular causes, those requiring extensive soft tissue releases or osteotomies and cases with relapsed or recurrent CTEV were excluded. Casting was initiated following maternal manipulation for one to two weeks. Pirani scores were recorded initially and weekly till correction. After deformity correction, anthropometric measurements (femur and tibia length, calf girth and foot length and foot height) were recorded and compared to the opposite normal limb. Results: Only four patients showed a difference in their femur length while difference in tibia length was noted in 10 patients which were statistically not significant. A significant difference was found in the calf girth, foot height and foot length affecting 28, 43 and 42 patients respectively. Conclusion: Patients with unilateral clubfoot treated with Ponseti’s correction tend to have anthropometric difference between the affected and the unaffected extremity. While there is a relative sparing of femur and tibia length, calf girth, foot height and foot length are consistently less compared to the unaffected side.
Evaluation of Hindfoot Alignment on Lateral Weightbearing x-rays: A Novel Prospective In Vivo Study
Authors: Zhu Mingjie , Far Munib D. , Pham Kenneth , Chiem Gavin , Carpenter Melissa L. , Cephers Candace , Myerson Mark , Li Shuyuan 
Published: December 2023

Category: Hindfoot; Midfoot/Forefoot Introduction/Purpose: In clinical practice and research, there are several scenarios when a hindfoot alignment view weightbearing XR is not obtained whether as a result of a lack of resources, technology, in retrospective studies when a hindfoot view was not obtained, as well as in many practices where a hindfoot view XR is not considered a routine examination for foot and ankle disorders. A lateral weightbearing radiograph however is almost routinely obtained, and the goal of this study was to correlate the hindfoot alignment angle with measurements on lateral weightbearing images. Methods: Four volunteers (8 feet) with flexible feet and ankles and no symptoms, nor significant trauma & surgical history in their lower limbs were recruited for this study. A portable fluoroscopy machine (Smart C, Turner Imaging, Salt Lake City, USA) was used for imaging. The participant was asked to stand on different custom wooden wedges with the angle changed every 5 degrees from 30 degrees of varus to 30 degrees of valgus and a weightbearing lateral image was taken for each position. The hindfoot alignment was measured using a skin marker which had been drawn prior to initiation of the imaging, and the angular changes of the hindfoot was measured with the placement of each wedge placed. All standardized measurements of the midfoot and hindfoot were obtained on the lateral images. Results: With the hindfoot positional changes between 30o of varus to 30o of valgus, there was a gradual measurable change in the subtalar joint, with corresponding changes in the midfoot and hindfoot. There was a significant linear correlation between the hindfoot alignment angle and all radiographic parameters on lateral images. When the hindfoot alignment angle increased by 1 degree in the valgus direction, there was 0.49o decrease in the pitch angle, 0.58o of decrease in the middle vs posterior facet angle, 0.06o of decrease in the proximal cuneiform/cuboid height, 0.40o of decrease in the proximal cuneiform/5th Metatarsal height, 0.40o of increase in the fifth metatarsal/cuboid height, 0.009o of increase in the sinus tarsi/lateral process height, and 0.015o increase in Cuboid/Anterior Process Height. (Figure 1) Conclusion: The lateral weightbearing XR can be used to predict the status of the hindfoot alignment, and this study has proven that this can be none not only qualitatively but also quantitatively. This novel research can provide our colleagues with linear regression equations to correlate the lateral imaging metrics with the hindfoot alignment angle. Further study with a larger sample size and participants with different types of hindfoot deformities is needed to help develop an algorithm that would help both clinical practice and research.
Favorable Outcomes Following Extra-Corporeal Shockwave Therapy for Chronic Non-Insertional Achilles Tendinopathy Compared to Chronic Insertional Achilles Tendinopathy: A Retrospective Review
Authors: Butler James J. , DeClouette Brittany , Walls Raymond J. , Jejelava George , Zheng Danny , Azam Mohammad T. , Kennedy John G. 
Published: December 2023

Category: Ankle; Basic Sciences/Biologics Introduction/Purpose: Extracorporeal shockwave therapy (ESWT) is a non-invasive treatment modality that is utilized in the treatment of chronic Achilles tendinopathy (AT). The purpose of this study was to retrospectively assess outcomes following ESWT for both NAT and IAT at greater than 1-year follow-up, and to identify potential predictors of outcomes. Methods: Chart review was conducted to identify patients who underwent ESWT for AT with a minimum of 1-year follow-up. Data collected and assessed included: patient demographics, pathological characteristics, treatment characteristics, Victorian Institute of Sports Assessment-Achilles (VISA-A) and visual analog scale (VAS) scores and failures. Linear regression was performed to identify potential predictors of outcomes. Survival analysis was conducted using Kaplan Meier curves. Fifty-two cases of IAT and 34 cases of NAT were included. The mean follow-up in the NAT cohort was 22.3±10.2 months and the mean follow-up time in the IAT cohort was 26.8±15.8 months. Results: Improvements in VISA-A and VAS scores were observed in the NAT cohort at 6 months follow-up and at final follow-up (p < 0.01). Improvements in VISA-A scores and VAS scores were recorded in the IAT cohort at 6 months follow-up which subsequently deteriorated at final follow-up. In the NAT cohort, the failure rate at 6 months follow-up was 11.8% which increased to 29.4% at final follow-up. In the IAT cohort, the failure rate at 6 months follow-up was 32.7% which increased to 59.6% at final follow-up. Predictors of poor outcomes in the NAT cohort included pre-ESWT subjective clinical score, male, presence of cardiovascular risk factor, and increasing MRI severity. Predictors of poor outcomes in the IAT cohort included pre-ESWT subjective clinical score and increasing MRI severity. Conclusion: This study found that superior subjective clinical outcomes together with a lower failure rate maintained over 1 year in the NAT cohort compared to the IAT cohort. This may implicate ESWT as a temporising treatment in IAT and a longer term solution in patients with NAT.
Heat Generation and Risk of Thermal Necrosis during Minimally Invasive Hallux Valgus Correction Utilizing a Shannon Burr: A Cadaveric Study
Authors: Hall SarahRose , Encinas Rodrigo , Cantrell Anthony C. , Jackson J. Benjamin , Gonzalez Tyler 
Published: December 2023

Category: Midfoot/Forefoot; Other Introduction/Purpose: Minimally invasive (MIS) bunion correction is growing in popularity as a treatment option of hallux valgus deformities. This technique has been shown to help with post-operative pain and improve functional outcomes. Despite these benefits there are concerns that the Shannon burr may lead to excess heat generation, thermal necrosis of bone and potentially increase the risk of nonunion. The purpose of our study was to assess the heat generation while using a Shannon burr during MIS first metatarsal osteotomies. Methods: Four below knee cadavers were utilized and osteotomies of the distal and proximal aspects of each of the first metatarsal were performed utilizing a 2mm x 20mm Shannon burr under fluoroscopic guidance. 3 K-type thermocouples were placed in each metatarsal, one distal, one in between and one proximal to the osteotomy sites. Temperatures were evaluated during the entire burring process and after to assess heat dissipation and total heat generated. Three different techniques of burring were utilized, 1. Continuous without irrigation, 2. Continuous with irrigation and 3. Pulse burring technique with irrigation (20 seconds on, 10 seconds off). Results: The pulse burring technique with irrigation showed the overall lowest max temperature and change in temperature compared to the other techniques. Average burr time, maximum heat generation and overall change in heat was 86.2 seconds, 102.4 °F and 78.9 °F for all trials. Conclusion: The pulse burr technique with irrigation generated less heat than both continuous burring with and without irrigation. There was an overall trend toward higher heat generation with longer burr times regardless of irrigation and burring technique. Utilizing a Shannon burr with pulse burring and irrigation can minimize heat generation and potentially decrease the risk of thermal necrosis of bone.
K-Wire Fixation vs Implant Device Fixation for Hammertoe Deformity: A Systematic Review and Meta-Analysis
Authors: Butler James J. , Konar Kishore , Azam Mohammad T. , Kennedy John G. 
Published: December 2023

Category: Lesser Toes; Other Introduction/Purpose: The purpose of this systematic review was to compare the clinical and radiological outcomes between K- Wire fixation and implant device fixation for the management of hammertoe deformity. Methods: During November 2022, the PubMed, Embase and Cochrane library databases were systematically reviewed to identify clinical studies examining outcomes following either K-Wire fixation and implant device fixation for the treatment of hammertoe deformity at a minimum of 1-year follow-up. Data regarding surgical characteristics, subjective clinical outcomes, radiological outcomes, complications and failure rates were extracted and analysed. 19 studies were included for quantitative analysis, of which 4 studies were included for qualitative analysis. Results: In total, 1343 patients (3468 feet) underwent K-Wire fixation and 456 patients (664 feet) underwent implant device fixation for the management of hammertoe deformity.The osseous union rate in the K-wire cohort was 71.3% versus 74.8% in the implant device cohort. The complication rate in the K-wire cohort was 9.7% versus 29.3% in the implant device cohort. The failure rate in the K-wire cohort was 8.6% versus 6.5% in the implant cohort. The secondary surgical procedure rate in the K-wire cohort was 8.3% versus 3.6% in the device cohort. Qualitative analysis found no difference in osseous union rates (RR=0.5832; 0.0830-4.0985; p=0.3562), complication rates (RR=1.12; 0.11-11.34; p=0.8571), failure rates (RR=0.87; 0.04-21.86; p=0.8746) nor secondary surgical procedure rates (RR=1.05; 0.06-18.32; p=0.9487) between the K-wire cohort and device cohort. Conclusion: This systematic review and meta-analysis demonstrated improvement in clinical and radiographic outcomes following both K-wire fixation and implant device fixation for hammertoe deformity. Qualitative analysis found no significant difference in osseous union rates, complication rates, failure rates nor secondary surgical procedure rates between the 2 cohorts. However, the marked heterogeneity between the included studies and few high level comparative studies limits the generation of any robust conclusions. Further research is warranted to determine the optimal role of both K-wire fixation and implant device fixation in the management of hammertoe deformity.
Long-Term Outcomes of Infinity Total Ankle Arthroplasty Compared to Ankle Arthrodesis
Authors: Willegger Madeleine , Veljkovic Andrea , Younger Alastair , Wing Kevin , Penner Murray 
Published: December 2023

Category: Ankle Arthritis; Ankle Introduction/Purpose: End-stage ankle arthritis causes severe pain and disability. The most common treatment has been ankle arthrodesis (AA) with proven long-term results. However, total ankle arthroplasty (TAA) has become a viable option to preserve ankle joint motion, relieve pain and shield adjacent joints. And with the evolution of TAA prostheses over the past 2 decades, the use of TAA has been steadily increasing. Nevertheless, long term outcome data on the latest generation of TAA prostheses is scarce. The primary purpose of this study is to evaluate long-term PROMs after Infinity™ TAA and to compare the outcome to a patient cohort of ankle arthrodesis (AA) performed during the same time period. Methods: Patients with end-stage ankle arthritis who received surgical treatment with a primary Infinity TAA or AA performed between 2013-2015 were included in this study. All surgeries were performed by four fellowship trained foot and ankle surgeons. Patient reported outcomes (PROMs) comprising the AOS and SF-36 PCS score were prospectively collected for patients who were willing to enroll into the Canadian Orthopaedic Foot and Ankle Society (COFAS) database. PROM data was compared between the TAA and AA patient cohorts. Implant survivorship as well as revision and reoperation rates were also analyzed. Results: 33 patients/ankles underwent primary Infinity™ TAA and 59 patients/ankles underwent AA. Of these, 25 TAA and 46 AA were enrolled in the prospective database, 20 and 46 had PROMs available for follow-up, respectively. Mean TAA PROM follow- up was 6.8 years (3-9) and for AA 6.4 years (2-9). Mean TAA age at surgery was 67 years (54-85) and 58 years for AA (27-84). TAA total AOS score pre-operatively was 52.9, which improved significantly to 23.9. SF-36 PCS scores improved from 33.1 to 43.3. Pre- and post-operative PROMs were similar to the AA cohort. At clinical follow up of 8-10 years, TAA implant survival was 97% with one metal component exchange. Two TAA patients had two reoperations each. In the AA cohort, the reoperation rate was 10.8%. Conclusion: This is the first report on patient reported outcomes and implant survival at 8 or more years after primary Infinity™ TAA. PROMs remain significantly improved at long term follow-up and are comparable to a cohort of long-term AA patients. Revision rates were low with a single component revision in 33 patients resulting in an implant survivorship of 97%. Long-term outcome of the Infinity™ total ankle arthroplasty is promising.
Midterm Outcomes Talocalcaneal Coalition Arthroscopic Resection in Adults
Authors: Guo Qinwei 
Published: December 2023

Category: Arthroscopy; Hindfoot Introduction/Purpose: Arthroscopic resection3-term outcomes. However, the midterm outcomes of this approach remain uncertain. Methods: We performed a retrospective study of patients who underwent arthroscopic resection for symptomatic TCC. The patients were divided into 2 groups (group P, patients with isolated posterior facet coalition; and group MP, patients with both middle and posterior facet coalition). The preoperative and postoperative visual analog scale (VAS) scores for pain and American Orthopaedic Foot & Ankle Society (AOFAS) scale scores were calculated. The postoperative AOFAS and VAS scores between the 2 groups were analyzed. Patient satisfaction was also assessed. Results: Thirty-two patients were included in this study. The mean age at the time of surgery was 26.0 8.5 years, and the mean follow-up period was 56.9 18.0 months. Postoperative VAS and AOFAS scores improved more significantly than preoperative scores. At the final follow-up, excellent and good subjective outcomes were attained in 26 patients (81%), fair and poor outcomes in 6 patients (19%). There were no statistical differences in the postoperative AOFAS (91.0 7.0 vs 85.8 10.8, P = .532) and VAS score (2.1 1.7 vs 4.0 2.6, P = .537) between patients with the ratio of coalition/posterior facet more than or less than 50%. Conclusion: We found that TCC arthroscopic resection was generally associated with reasonable outcomes at midterm follow-up.