bluuebunny/crossref_metadata_2025_split huggingface dataset:
Slit tube responses and rock fracture characteristics in slit charge blasting under high in situ stress
Authors: Sui Zhe , Yang Liyun , Wu Lijun , Ding Chenxi 
Published: January 2025

AbstractDeep mining of natural resources, like coal, is increasingly utilizing directional blasting technology with slit charge for rock blasting at greater depths. This study, based on numerical simulation methods, analyzes the dynamic behavior of slit charge blasting in three aspects: slit tube dynamic response, hoop stress evolution, and crack propagation. According to research findings, the failure mode of the slit tube mainly manifests as a tensile fracture of the inner wall and a shear fracture at the end connection, where the end connection of the slit tube is the weak point of the overall structure. The dynamic response of the slit tube mainly exhibits radial response in the vertical direction of the slit and hoop response in the slit direction. The hoop tensile stress plays a crucial role in determining the spread of cracks caused by explosions. As the in situ stress increases, the peak hoop tensile stress reduces, and the peak hoop compressive stress increases. This hinders the propagation of cracks. In addition, the directional impact is most pronounced in the middle of the borehole, with the longest primary directional crack observed. Conversely, the directional impact is least favorable near the bottom of the borehole. When the in situ stress reaches 60 MPa, the purpose of directional fracture has not been achieved, suggesting combining presplit blasting for in situ stress relief to improve rock breaking efficiency.
Investigation of Fe(III) Complexes with Aminoguanidine Schiff Base Ligands as Biomimetic Catalysts and Sulphide Sensors
Authors: Ghosh Anwesha , Mondal Antu , Sengupta Swaraj , Jagličić Zvonko , Frontera Antonio , Kumar Chattopadhyay Shyamal 
Published: January 2025

AbstractTwo high spin Fe(III) complexes, [Fe(L1)2]Cl ⋅ H2O (1) and [Fe(L2)2]Cl ⋅ 4H2O ⋅ 0.5MeOH (2), of Schiff base ligands of aminoguanidine with salicylaldehyde and pyridoxal (isolated as the hydrochloride salts L1H2+Cl− and L2H32+Cl−2 respectively) are reported. X‐ray crystal structure of both the complexes along with their spectroscopic and variable temperature magnetic properties are also investigated. It is found that complex 2 shows stronger zero field splitting (D=9.5 cm−1) than complex 1 (D=5.5 cm−1), probably due to greater distortion of the Fe(III) coordination polyhedron in complex 2. TD‐DFT calculations are used to assign the electronic spectra of the complexes. Both the ligands show fluorescence at 450–460 nm with lifetime of nanosecond order and quantum yield of 0.04–0.07 at room temperature. Both the Fe(III) complexes are found to efficiently catalyze the aerial oxidation of DTBC to DTBQ with the turn over numbers 100–155 h−1, which is among the highest for mononuclear Fe(III) complexes. The complexes also act as very good fluorometric sensor for S2−, and the limit of detection (LOD) is in the octa‐molar region. The pH and temperature dependences of the sensing are also investigated.
Integrated Planning Model for Optimizing Investments in Hydrogen Infrastructure Deployment: A Case Study of Yangtze River Delta Region, China
Authors: Shen Weijie , Li Hua , Ding Hongjian , Zeng Ming , Xie Chuansheng , Zhang Xiaochun 
Published: January 2025

ABSTRACTThe hydrogen industry is of great significance for global energy system transition and decarbonization; thus, the holistic planning of hydrogen infrastructure from a supply chain level is necessary. To this end, first, the framework and methods in the hydrogen infrastructure deployment research were investigated systematically. Second, a hydrogen supply chain design (HSCD) model and a hydrogen refueling station location (HRSL) model were constructed. In view of the limitations of the two models, this paper reformulated the HRSL model through alternating the objective function and constraint, then proposed an integrated planning model using the ‐constraint method, which relaxed the assumption condition and expanded the decision‐making boundary of the original model, realizing the reasonable equilibrium of multiple segments. Finally, a case study was conducted using the Yangtze River Delta region as an example, and the main findings were as follows: (1) To meet the hydrogen demand of 25494t/d, the Yangtze River Delta region needs to build 94 coal gasification hydrogen plants, storage facilities with capacity of 12747t, transmission modes with capacity of 2333t/d, and 150 hydrogen refueling stations. (2) Railways have more advantages in large capacity and long‐distance hydrogen transmission. (3) Road segments with higher traffic flow often have a higher capture proportion. (4) The investment cost accounts for the majority of hydrogen production plant construction, which is 43.80%.
Meta‐Analysis of Consumer Willingness to Pay for Short Food Supply Chain Products
Authors: Mustapa Muhammad Adzran Che , Kallas Zein 
Published: January 2025

AbstractDue to their perceived benefits for health, the environment, the economy, and sustainability, in recent years there has been a growing interest on the part of researchers and policymakers in short‐food supply chains (SFSCs). However, a systematic review of the literature on this topic remains lacking. To address this gap, the study conducts a meta‐analysis to examine consumer willingness to pay (WTP) for SFSC products, taking into account various sociodemographic factors and sustainability attributes. On average, consumers are willing to pay a 34.5% premium for SFSC products. Key factors influencing WTP include gender, education, study year, age, region, product category, and sustainability attributes. Women exhibit higher WTP, and individuals with higher education levels also demonstrate increased WTP. Notably, WTP for SFSC products is lower before 2014, while younger consumers exhibit higher WTP overall. Consumers in Western Europe present higher WTP estimates compared to those in North America and other regions. In terms of sustainability attributes, organic products receive the highest WTP, with food categories such as meat, poultry, dairy products, and honey showing the highest estimates. These findings offer valuable insights for SFSC producers, marketers, and policymakers, guiding effective strategies to promote SFSC products within sustainable agri‐food systems.
Virucidal and Bactericidal Properties of Biocompatible Copper Textiles
Authors: Sandu Andrei‐Florin , Danilova Sofya , Acton Lauren , Cobley Andrew , Gould Phillip 
Published: January 2025

AbstractThe COVID‐19 pandemic highlights the global threat posed by emerging viruses, emphasizing the critical need for effective strategies to combat pathogen transmission. Moreover, alongside emerging viruses, the increasing threat of antimicrobial resistance further reinforces the need to develop novel methods for infection control. Anti‐pathogenic coatings on textiles offer a promising solution; in this study, three electroless copper‐plated fabrics are evaluated for their antipathogenic properties following International Standards Organisation (ISO) standards. Prior to electroless plating, materials are activated either by immersion in a Pd catalyst solution (material A) or by ink‐jet printing Cu/Ag catalyst along the weft (material B) or warp thread (material C). This study demonstrates that activation method influences the materials antipathogenic performance, with all materials achieving complete bactericidal/fungicidal neutralization within 30 min of incubation. Material B exhibits up to 4‐log virucidal effects within 1 h against viruses such as coronavirus (OC43, 229E), Influenza A (H1N1), and Rotavirus A. Furthermore, biocompatibility testing indicates that material B exhibited low in vitro cytotoxicity. Textile B demonstrates strong antibacterial results even after one year of accelerated aging with no significant difference (P = 0.74) in efficiency against MRSA, highlighting promising applications for infection control in clinical settings reducing pathogen transmission, nosocomial infections and the associated economic burden.
Distinguishing Neuromyelitis Optica Spectrum Disorders Subtypes: A Study on AQP4 and C3d Epitope Expression in Cytokine‐Primed Human Astrocytes
Authors: Alisch Marlen , Foersterling Franziska , Zocholl Dario , Muinjonov Bakhrom , Schindler Patrick , Duchnow Ankelien , Otto Carolin , Ruprecht Klemens , Schmitz‐Hübsch Tanja , Jarius Sven , Paul Friedemann , Siffrin Volker 
Published: January 2025

ABSTRACTNeuromyelitis optica spectrum disorders (NMOSD) are severe autoimmune conditions affecting the central nervous system. In a subset of cases, no autoantibodies are detectable with the currently used routine assays. This study aimed to determine whether the levels of expression of aquaporin‐4 (AQP4), excitatory amino acid transporter 2 (EAAT2), or complement C3/C3d and C5b‐9 in human astrocytes following incubation with patient sera under inflammatory conditions differ between the various NMOSD subtypes and whether such differences can help to identify autoantibody‐mediated cases of NMOSD. Levels of AQP4, EAAT2, complement C3/C3d and C5b‐9 epitope expression on human astrocytes pretreated with various cytokines were quantitatively analyzed via indirect immunofluorescence after exposure to sera from patients with AQP4‐IgG seropositive, MOG‐IgG seropositive, and AQP4/MOG‐IgG double seronegative NMOSD. Significant differences in AQP4 and C3d epitope expression were observed, with IL‐17A, IL‐10, and IL‐6 pre‐treatment notably influencing astrocytic responses. Using uniform manifold approximation and projection (UMAP), patients were classified into clusters corresponding to AQP4‐IgG seropositive, MOG‐IgG seropositive, or double seronegative NMOSD. These results demonstrate distinct astrocytic staining patterns across NMOSD subtypes, providing a potential diagnostic tool for distinguishing between autoantibody‐mediated astrocytopathy and other cases. These findings suggest specific pathogenic mechanisms linked to each NMOSD subtype, which may have implications for tailoring therapeutic strategies based on cytokine involvement and astrocyte reactivity.
Achieving Pressure Consistency in Mechanochemical Simulations of Chemical Reactions Under Pressure
Authors: Bentrup Jonas , Weiß Rahel , Zeller Felix , Neudecker Tim 
Published: January 2025

ABSTRACTThe eXtended Hydrostatic Compression Force Field (X‐HCFF) is a mechanochemical approach in which a cavity is used to exert hydrostatic pressure on a target system. The cavity used in this method is set up to represent the van der Waals (VDW) surface of the system by joining spheres sized according to the respective atomic VDW radii. The size of this surface can be varied via a scaling factor, and it can be shown that the compression forces exerted in X‐HCFF in its current implementation depend on this factor. To address this dependency, we have developed a rescaling formalism for the applied forces, allowing us to drastically reduce the dependency of the compression forces on the chosen scaling factor. Independency from the scaling factor is important, as the scaling of the VDW spheres is often used to ensure an overlap of cavities in supramolecular complexes, which is necessary for the simulation of chemical reactions. Our rescaling formalism reduces the empiricism of the X‐HCFF approach and boosts its applicability in the field of computational high‐pressure chemistry.
Dirty Environment, Dark Mood: Exploring the Link Between Perceived Environmental Pollution and Depression Risk
Authors: He Yuhang , He Huawei , Li Haoyin , Yang Jinran 
Published: January 2025

ABSTRACTTo explore the impact of perceived environmental pollution on individual depression risk and the mechanisms involved, particularly the mediating roles of health level and life confidence. Ordinary least squares, Ologit, and Oprobit models were employed to analyze data from the 2020 China Family Panel Studies to test the hypothesized relations outlined above. The findings indicate that perceived environmental pollution significantly increases depression risk (β = 0.052, p < 0.01). Both health level and life confidence serve as mediators in this relationship, forming a serial mediation mechanism. This study reveals the negative impact of perceived environmental pollution on mental health. It emphasizes the importance of improving public health levels and life confidence and provides an evidence base for related policies.
Extracellular Vesicles From Bone Marrow‐Derived Macrophages Enriched in ARG1 Enhance Microglial Phagocytosis and Haematoma Clearance Following Intracerebral Haemorrhage
Authors: Hu Libin , Chen Zihang , Lu Jianglong , Jiang Shandong , Lin Haopu , Zhou Jiayin , Wang Ning , Ding Chao , Ni Weifang , Peng Haitao , Li Yin , He Xuchao , Li Jianru , Jing Chaohui , Cao Yang , Zhou Hang , Yan Feng , Chen Gao 
Published: January 2025

ABSTRACTMicroglial phagocytosis of haematomas is crucial for neural functional recovery following intracerebral haemorrhage (ICH), a process regulated by various factors from within and outside the central nervous system (CNS). Extracellular vesicles (EVs), significant mediators of intercellular communication, have been demonstrated to play a pivotal role in the pathogenesis and progression of CNS diseases. However, the regulatory role of endogenous EVs on the phagocytic capacity of microglia post‐ICH remains elusive. Utilising multi‐omics analysis of brain tissue‐derived EVs proteomics and single‐cell RNA sequencing, this study identified that bone marrow‐derived macrophages (BMDMs) potentially enhance microglial phagocytosis via EVs following ICH. By blocking BMDMs and reducing ARG1 in BMDM‐derived EVs, we demonstrated that BMDMs facilitate erythrophagocytosis by delivering ARG1 to microglia via EVs post‐ICH. EVs‐carried ARG1 was found to augment phagocytosis by promoting RAC1‐dependent cytoskeletal remodelling in microglia. Collectively, this research uncovers an intercellular communication pathway from BMDMs to microglia mediated by EVs post‐ICH. This provides a novel paradigm for EV‐mediated intercellular communication mechanisms and suggests a promising therapeutic potential for BMDM‐derived EVs in the treatment of ICH.
The Presence of a Shelter in an Open Field Test Has Differential Effects on the Behavior and Stress Response of Two Mouse Species
Authors: Monarca Rita I. , Silva Ricardo F. B. , Gabriel Sofia I. , Cerveira Ana M. , von Merten Sophie 
Published: January 2025

ABSTRACTThe open field test (OFT) is frequently used in research to assess anxiety‐like behavior and locomotor activity. Its simple design can lead to the misconception that it is a standardized procedure comparable between laboratories. However, some modifications in the setup can cause changes in behavior. Different species might also react differently to the modifications introduced. There is thus need for a better understanding of the impact of modifications and their value for the species in question. Here, we tested two closely related mouse species, Mus musculus and Mus spretus, in an OFT with and without the presence of a shelter. We assessed mouse exploratory behavior through the analysis of multiple behavioral traits, and stress response through the measurement of circulating cortisol levels. Both species had elevated cortisol levels during the OFT in contrast to control animals which were not exposed to the OFT. While the presence of a shelter in the OFT increased the exploratory behavior in both mouse species, M. spretus, but not M. musculus, showed a reduction in cortisol levels. Also, other measured behaviors show a rather proactive coping strategy of the commensal M. musculus in contrast to a reactive strategy of the non‐commensal M. spretus. Our study revealed a strong species‐specific influence of the OFT design on the resulting behavior and stress levels of mice, illustrating the importance of OFT designs to account for the characteristics of the species under study. The addition of a shelter might be considered to improve experimental results by promoting animal welfare.
Using an Oral Sugar Test to Biologically Validate the Use of a Commercial Enzyme Immunoassay to Measure Salivary Insulin in Western Lowland Gorillas (Gorilla gorilla gorilla)
Authors: Tennant Kaylin S. , Less Elena H. , Raghanti Mary Ann , Amendolagine Laura A. , Lukas Kristen E. , Willis Mark A. , Dennis Patricia M. 
Published: January 2025

ABSTRACTNoninvasive evaluations of hormones can contribute to the assessment of health and welfare of animals. Variations in insulin levels and sensitivity, for example, have been linked to health concerns in non‐human and human primates including insulin resistance, diabetes, and heart disease, the leading cause of death in zoo‐housed gorillas. Few published studies have assessed insulin concentrations in western lowland gorillas (Gorilla gorilla gorilla), and all did so using serum. Anesthesia is typically required to collect blood samples from zoo‐housed gorillas, limiting sampling frequency and restricting samples to the fasted state. The ability to measure insulin levels in saliva would eliminate these constraints and provide a minimally invasive means for monitoring this hormone. The purpose of this study was to analytically and biologically validate the measurement of insulin in saliva of western lowland gorillas using a commercially available enzyme immunoassay. For validation, an oral sugar test was conducted on five adult gorillas residing at Cleveland Metroparks Zoo. Such assessments are common practice in both human and equine medicine to evaluate the body's insulin response to ingestion of sugars. The test involved measuring salivary insulin at timed intervals before and after gorillas consumed doses of sugar. Salivary insulin levels increased from 15 min post‐sugar ingestion and peaked after 90 to 120 min. One female had a high response and peaked at 990.21 mU/L. The other four gorillas had peaks between 49.82 and 167.04 mU/L. The assessment provided a biological validation for the measurement of salivary insulin in western lowland gorillas.
Increasing trends of cannabinoid hyperemesis syndrome in youth: The grass is not always greener
Authors: Jack Benjamin , Susi Apryl , Reeves Patrick , Nylund Cade M. 
Published: January 2025

AbstractThis study investigated trends in suspected cannabinoid hyperemesis syndrome (CHS)‐related emergency department visits among youth (15–24 years old) in the United States between 2006 and 2020. Using data from the Nationwide Emergency Room Sample, over 55,000 suspected CHS‐related visits were identified, with an average annual increase of 28.1% per year. This aligns with rising cannabis use and potency across the nation. Subjects in the western region, males, and those with public insurance were more likely to present with suspected CHS. These findings highlight the growing public health concern of CHS and emphasize the need for increased awareness among healthcare providers, particularly regarding the potential link between CHS and chronic cannabis use in youth. Further research is needed to understand the underlying mechanisms and risk factors associated with CHS as well as the impact of cannabis public policy on health outcomes.
Hidden hunger: from a plant biologist's perspective
Authors: Kam Melissa Yit Yee 
Published: January 2025

AbstractIn recent years, changes in dietary patterns from an omnivore diet to a moderate‐to‐restrictive diet that includes more plant food are becoming popular for various reasons and the associated health benefits. Despite the increased consumption of plant food as recommended by these seemingly healthy diets, micronutrient deficiency is still prevalent particularly among the health‐conscious populations. The aim of this review is to help guide interventions by understanding micronutrient deficiency trends from a dietary habit and plant physiology context. In this review, the author discusses how modern agricultural practices coupled with climate change, and with particular emphasis on the extreme dietary habits that lack variation and excessive consumption, may contribute to an increased ingestion of antinutrients which in turn potentially exacerbate vitamin and mineral deficiencies. While plants possess a wide range of secondary metabolites that exert beneficial health effects, some of these compounds are also antinutrients that interfere with the digestion and absorption of nutrients and micronutrients. Furthermore, the article also raises questions concerning the fate of antinutrient traits in future crops that were to be redesigned with improved stress tolerance, and the impacts it may have on human nutrition and the environment. © 2025 Society of Chemical Industry.
Anticoagulant rodenticides may affect fisher population trends in the northeastern United States
Authors: Silveira Georgianna , Frair Jacqueline L. , Cohen Jonathan , Watson Mandy , Tate Patrick , Royar Kim , Bernier Chris , Schuler Krysten 
Published: January 2025

AbstractRegrowth of forests across the northeastern United States in recent decades has allowed for range expansion of many forest‐dependent mammals in the region. However, these contemporary forests have smaller patch sizes, putting humans in closer proximity to previously remote forested areas, and different species compositions and structure compared to historical forests. These conditions pose an increased risk of exposure to anthropogenic disturbances and contaminants for forest‐dwelling wildlife. We evaluated the relationship between contemporary forest conditions and anticoagulant rodenticides (ARs) on recent population trends for fishers (Pekania pennanti). We acquired a snapshot of recent population trends for fishers across New York, Vermont, and New Hampshire, USA, using standardized catch‐per‐unit‐effort (CPUE) data from the regulated fall harvest spanning 2016‐2020, when harvest regulations remained consistent across the states. We used regression models to relate the probability of CPUE increase to measures of forest habitat (age, structure, productivity), length of winter snow cover, and human disturbance (land use patterns and AR detection). The top model indicated that the probability of CPUE increase declined 43% for every 10% increase in the percent of the population exposed to at least 1 AR and by 24% for every 1‐day increase in the length of winter snow cover, while measures of forest conditions had no significant relationship. The relationship between AR detection and suppressed CPUE increase is compelling, as few mammalian studies effectively link the detection of AR residues in animal tissues to population‐level performance in the wild. Nevertheless, longer time frames are required to fully understand population trends and their drivers across heterogeneous landscapes. We recommend the fisher as a model species for longer‐term monitoring of AR detections and for comparing outcomes of measures potentially designed to reduce AR impacts on wildlife in this region.