bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kaleidofin
Authors: Mendonca Valerie , Sharma Supriya , Jain A. K. 
Published: November 2023

Kaleidofin was co-founded in 2017 by Puneet Gupta and Sucharita Mukherjee; former CFO and CEO of IFMR (Institute for Financial Management and Research) Holdings Pvt Ltd. As part of their roles at IFMR, Gupta and Mukherjee focused on designing products and developing technology to push for financial inclusion. In their field interactions, the co-founders had an epiphany of the challenges faced by people while trying to save towards important life goals. They saw an opportunity in the large segment of financially under-served people in India and quit their jobs to start Kaleidofin. Kaleidofin was conceptualised as a digital platform that offers customised financial solutions to help customers meet their life goals. The start-up partnered with mutual fund companies for solutions on one hand and network partners (NGOs, microfinance organizations, cooperative banks) on the other for access to their existing customers.
Kaleidofin grew from 50 customers in January 2018 to 15,000 customers by March 2019. Aiming to grow to 1 million customers in the next 30 months Kaleidofin faces a dilemma about its future course. The start-up could continue to grow by expanding its current target segment which is the low-income households and preserve its vision at the risk of increasing costs. The second option would be to look at other potential target segments, such as, middle-income households and risk diluting their vision. The case study highlights the unique customer-centric model of Kaleidofin and the need for start-ups to understand the value proposition of their products/services.
Female leadership and ESG performance of firms: Nordic evidence
Authors: Yahya Habeeb 
Published: November 2023

Purpose
This paper aims to focus on the relationship between female leadership and the environmental, social and governance (ESG) performance of firms. Specifically, the study examines if firms with women as chief executive officers (CEOs) and/or board chairpersons have higher environmental and social scores.

Design/methodology/approach
The study uses data on publicly listed Nordic firms in a panel regression approach to establish the relationship between female leadership and the environmental and social performance of firms.

Findings
The result of this study shows that women have a leadership characteristic that increases the weighted average of environmental (E) and social (S) performance of a firm. In particular, pillar score results indicate a positive relationship between female CEOs and the social scores of a firm but no relationship between a female board chairperson and the environmental or social scores of a firm. This implies that gender-based differences affect the CEO’s success, especially in a firm’s social performance. Further analyses show a more significant impact on the E and S performance when a woman replaces a man as CEO of a firm.

Originality/value
While prior research has explored various aspects of gender diversity in corporate leadership and its potential impact, the focus on the Nordic context in this study provides a unique perspective, given the region’s distinct business environment and societal factors. In addition, by examining the collective influence of female leaders and both female CEOs and board chairpersons separately, this study provides a nuanced understanding of how different leadership roles may impact a firm’s ESG performance.
Management of gallstone disease and chronic liver diseases during the COVID-19 outbreak in Ukraine: an ecological study
Authors: Bogomaz Volodymyr , Natrus Larysa , Ziuz Nataliia , Starodub Tetiana 
Published: November 2023

PurposeThe purpose of this paper is to estimate the possible impact of the COVID-19 pandemic on the hospitalization and hospital mortality of the patients with gallstone disease and chronic liver diseases (CLD) in the worst pandemic period in Ukraine.Design/methodology/approachA retrospective comparative analysis of annual reports data of all economy subjects, which conducted economic activity in medical practice for 2019 and 2021. Data was accepted from the Ministry of Health of Ukraine, the National Security and Defense Council of Ukraine (NSDC) and the State Statistics Service of Ukraine (SSSU).FindingsThe total hospitalization rates for diffuse liver disease and cholelithiasis significantly decreased during the peak of the COVID-19 pandemic in Ukraine, compared to the values of 2019. At the same time, the rates of in-hospital mortality for these diseases have significantly grown. Also, various proportions of similar trends were described in other countries during the first wave of the pandemic.Originality/valueThis paper highlights the fact that regulatory restrictions and the fear of the population of referring to healthcare facilities considering the high risk of getting an infection had significant disruption to medical care for patients with gallstone disease and CLD. Improving the management of medical resources and strengthening all kinds of institutions in the healthcare system must be thought about if similar challenges appear in the future.
Research of operation mode of high-speed trains on the effect of rail wear evolution law
Authors: Qi Yayun , Wang Ruian , Cui Xiaolu , Sang Hutang , Mao Wenhui 
Published: November 2023

Purpose
With the increased speed and mileage of high-speed lines, the problem of rail wear is increasing. In actual operation, a large number of abnormal wear phenomena occur on both vehicles and rails during fixed line operation; therefore, the purpose of the study is to explored the rail wear for a variety of vehicles running in mixed operation.

Design/methodology/approach
This paper used the universal mechanism multibody dynamics software to establish the CRH2 high speed train (HST) and the CRH3 HST vehicle dynamic models, respectively. The mixed running of HSTs on the effect of rail wear evolution law was analyzed. The rail wear of the two vehicles with different curve radii, different wheel diameters and different under-rail stiffness was compared and analyzed.

Findings
The result showed that the rail wear of CRH3 HST is greater than that of CRH2 HST. The rail wear in the tangent track under mixed operation conditions is 25.4% less than when CRH3 HST operated independently. When there is a 1-mm wheel diameter difference, the maximum rail wear of CRH2 HST and CRH3 HST increases by 263% and 44%, respectively. The amount of rail wear is proportional to the under-rail stiffness, and the position of the maximum wear is almost unchanged.

Originality/value
Most studies on the evolution law of rail wear are conducted for a single vehicle type and a single line. This study explored the mixed running of HSTs on the effect of rail wear evolution law.

Peer review
The peer review history for this article is available at: https://publons.com/publon/10.1108/ILT-08-2023-0276/
The effects of working from home during the COVID-19 pandemic on work–life balance, work–family conflict and employee burnout
Authors: Khalid Afaf , Raja Usman , Malik Abdur Rahman , Jahanzeb Sadia 
Published: November 2023

PurposeDespite the extent of working from home (WFH) during the coronavirus disease 2019 (COVID-19) pandemic, research exploring its positive or negative effects is exceptionally scarce. Unlike the traditional positive view of WFH, the authors hypothesize that WFH during the COVID-19 pandemic has triggered work–life imbalance and work–family conflict (WFC) for employees. Furthermore, the authors suggest that work–life imbalance and WFC elicit burnout in employees.Design/methodology/approachUsing a time-lagged design, the authors collected data in three waves during the peak of the first wave of the COVID-19 pandemic to test the authors' hypotheses.FindingsOverall, the authors found good support for the proposed hypotheses. WFH had a significant positive relationship with burnout. WFH was negatively related to work–life balance (WLB) and positively related to WFC. Both WLB and WFC mediated the effects of WFH on burnout.Practical implicationsThis is one of the earliest studies to explore the harmful effects of involuntary WFH and identify the channels through which these effects are transmitted. The practical implications can help managers deal with the adverse effects of WFH during and after the COVID-19 crisis.Originality/valueThe authors' results significantly contribute to the research on WFH and burnout and present important implications for practice and future research.
From ‘United Stabilisation Fund’ to ‘International Monetary Organisation’: the Forgotten Chinese Plan and Its Contributions to the Creation of the International Monetary Fund
Authors: ZHANG SHIWEI , WANG ZHAODONG 
Published: November 2023

AbstractChina's function in the establishment of the International Monetary Fund (IMF) and the World Bank (WB) has been underrated for a long time. It is argued either that China contributed little to the establishment or that its main effort could be accredited to Arthur N. Young, an American financial advisor to the Chinese government. A close examination of bilingual archival documents challenges these arguments. In fact, the Chinese government formulated proposals of several versions and managed to have most of its claims accepted at the Bretton Woods conference. More importantly, Chinese claims surpassed their own concerns and had a broader meaning taking into account the general quests of war‐torn and undeveloped countries. Revisiting this part of history can deliver a balance to the traditional Anglo‐American‐focused narrative regarding the IMF and WB and enrich the historical context to assist our understanding of China's current pursuits and conduct in the realm of multilateral economic cooperation.
Long‐lasting mechanical hypersensitivity and CRF receptor type‐1 neuron activation in the BNST following adolescent ethanol exposure
Authors: Bertagna Natalia B. , Wilson Lisa , Bailey Connor K. , Cruz Fabio C. , Albrechet‐Souza Lucas , Wills Tiffany A. 
Published: November 2023

AbstractBackgroundAdolescent alcohol use can produce long‐lasting alterations in brain function, potentially leading to adverse health outcomes in adulthood. Emerging evidence suggests that chronic alcohol use can increase pain sensitivity or exacerbate existing pain conditions, but the potential neural mechanisms underlying these effects require further investigation. Here, we evaluate the impact of chronic ethanol vapor on mechanical sensitivity over the course of acute and protracted withdrawal in adolescent and adult male and female mice, and its potential association with alterations in corticotropin‐releasing factor (CRF) signaling within the bed nucleus of the stria terminalis (BNST).MethodsAdolescent and adult male and female mice underwent intermittent ethanol vapor exposure on 4 days/week for 2 weeks. Mechanical thresholds were evaluated 5 h and 7, 14, 21, and 28 d after cessation of ethanol exposure using the von Frey test. For mice with a history of adolescent ethanol exposure, brains were collected for in situ RNAscope processing after the final test. Messenger RNA expression of c‐Fos, Crfr1, and Crf in the BNST subregions was examined.ResultsExposure to intermittent ethanol vapor induced persistent mechanical hypersensitivity during withdrawal in both adolescent and adult mice. Notably, the effect was more transient in mice exposed to ethanol during adulthood, resolving by day 28 after ethanol exposure. Furthermore, both male and female mice with a history of adolescent ethanol exposure exhibited increased activation of CRF receptor type 1 (CRFR1) neurons within the dorsolateral BNST.ConclusionsOur results support the conclusion that intermittent ethanol exposure can induce mechanical hypersensitivity, potentially through the activation of BNST CRFR1 neurons. These findings provide a basis for future studies aimed at evaluating specific subpopulations of BNST neurons and their contribution to pain in individuals with a history of alcohol use.
Renal cortex microperfusion evaluated by laser speckle contrast imaging in an ex vivo perfused kidney model—A proof‐of‐concept study
Authors: Arildsen Maibritt Meldgaard , Thrane Lars , Staulund Jesper , Eijken Marco , Jespersen Bente , Postnov Dmitry , Al‐Mashhadi Rozh H. , Pedersen Michael 
Published: November 2023

AbstractBackgroundValidated quantitative biomarkers for assessment of renal graft function during normothermic machine perfusion (NMP) conditions are lacking. The aim of this project was to quantify cortex microperfusion during ex vivo kidney perfusion using laser speckle contrast imaging (LSCI), and to evaluate the sensitivity of LSCI when measuring different levels of renal perfusion. Furthermore, we aimed to introduce LSCI measurements during NMP in differentially damaged kidneys.MethodsEleven porcine kidneys were nephrectomized and perfused ex vivo. Cortex microperfusion was simultaneously monitored using LSCI. First, a flow experiment examined the relationship between changes in delivered renal flow and corresponding changes in LSCI‐derived cortex microperfusion. Second, renal cortical perfusion was reduced stepwise by introducing a microembolization model. Finally, LSCI was applied for measuring renal cortex microperfusion in kidneys exposed to minimal damage or 2 h warm ischemia (WI).ResultsCortex microperfusion was calculated from the LSCI‐obtained data. The flow experiment resulted in relatively minor changes in cortex microperfusion compared to the pump‐induced changes in total renal flow. Based on stepwise injections of microspheres, we observed different levels of cortex microperfusion that correlated with administrated microsphere dosages (r2 = 0.95–0.99). We found no difference in LSCI measured cortex microperfusion between the kidneys exposed to minimal damage (renal cortex blood flow index, rcBFI = 2090–2600) and 2 h WI (rcBFI = 2189–2540).ConclusionsBased on this preliminary study, we demonstrated the feasibility of LSCI in quantifying cortex microperfusion during ex vivo perfusion. Furthermore, based on LSCI‐measurements, cortical microperfusion was similar in kidneys exposed to minimal and 2 h WI.
Cream versus ointment: Randomized single‐blinded study on the adherence to treatment with topical methylprednisolone aceponate
Authors: Gregersen Deborah Maria , Peckruhn Melanie , Breternitz‐Gruhne Maria , Schiller Isabella , Schumacher Ulrike , Franke Lisa , Bahr Viola , Tittelbach Jörg , Elsner Peter 
Published: November 2023

AbstractBackgroundOverall adherence in the treatment of chronic dermatoses is poor. Textbooks state an adherence dependence on galenics.Trial DesignProspective, randomized, parallel‐grouped, single‐blinded (investigator), monocentric clinical trial (phase IV) on the adherence to treatment of chronic mild to moderate hand eczema with topical methylprednisolone aceponate (MPA, Advantan®) in different vehicles.Objectives and EndpointsPrimary objective was the assessment of the adherence depending on vehicle type in patients with chronic hand eczema. Secondary objective was improvement after a 4‐week treatment period. Primary Endpoint Adherence is defined as the percentage of patients applying at least aimed daily dose. Prescribed daily dose was defined as the planned number of applications per day (1) * surface (measured) * aimed amount per application (mg/cm2). Truly applicated daily dose was evaluated as individual mean amount per dose * individual mean number of applications per day.Adherence was assumed, if
truly applicated daily dose is at least 75% of the prescribed daily dose and
the individual mean number of applications per day is at least 0.85.
Secondary Endpoint Efficacy was measured by improvement of Hand Eczema Severity Index (HECSI) and Investigator's Global Assessment (IGA) after a 4‐week treatment period and in addition to Quality of Life in Hand Eczema Questionnaire (QOLHEQ) and Visual Analogue Scale (VAS) to assess pruritus.MethodsNumber of participants randomized to each group 40, 80 total. Group 1 MPA‐C: Methylprednisolone aceponate 0.1% cream and barrier repair emollient (Bepanthen® Sensiderm). Group 2 MPA‐FO: Methylprednisolone aceponate 0.1% fatty ointment and barrier repair emollient (Bepanthen® Sensiderm). Adherence to treatment was compared via Fisher's exact test.ResultsOf the patients, 48% were adherent according to our definition. There was no significant difference between MPA‐C (42.1%) and MPA‐FO (54.1%; p = 0.36; group difference—12.0%, 95% CI—34.3%–11.5%). Generalized‐linear‐model‐analysis of adherence to study treatment with factors emollient use, treatment, time and treatment‐time interaction showed a parallel between adherence and amount of emollient use (odds ratio 1.74, p = 0.0038; 95% CI—1.22–2.52). Improvement of hand eczema was seen according to clinical scores without remarkable differences between the groups.ConclusionsNo dependence of adherence on galenics of topical treatment of chronic hand eczema could be proved. Patients who use more emollient tend to be more adherent to the topical treatment.
The impact of pseudoephedrine regulation at Australian pharmacies through Project Stop: A narrative review
Authors: Brookfield Samuel , Gartner Coral 
Published: November 2023

AbstractIssuesProject Stop, a real‐time monitoring program for pseudoephedrine‐containing medicines, was initiated in 2005 by the Pharmacy Guild of Australia in collaboration with police in the state of Queensland. The program implemented an online database to record pseudoephedrine purchases (and attempted purchases) to prevent large‐scale diversion to methamphetamine production.ApproachThis narrative review aims to understand the overall impact of Project Stop, what evidence exists for this kind of intervention in Australia, and what lessons can be learned from its introduction. Systematic database searches were conducted in Embase, PubMed, Web of Science and Google Scholar, with 20 relevant sources selected for inclusion.Key FindingsProject Stop successfully prevented some pseudoephedrine from being diverted from pharmacies to methamphetamine production. The intervention has been most effective in jurisdictions that made the program mandatory. Project Stop was also associated with a temporary decline in clandestine laboratory seizures in Queensland, changes in methamphetamine production methods and reduced voluntary treatment admissions for methamphetamine use. Implementation was not associated with an appreciable effect on secondary indicators, such as methamphetamine production and harmful use.ImplicationsFuture applications of a Project Stop model must ensure ongoing impact evaluation, assessment of its effect on individual's drug‐related behaviour and combine it with policies that address drug use as a health issue.ConclusionProject Stop has been narrowly successful in terms of reducing pseudoephedrine diversion and demonstrates the potential for third‐party policing practices directed at the consumer level, in collaboration with healthcare practitioners, rather than only regulating precursor wholesalers.
Indifference, Indeterminacy, and the Uncertainty Argument for Saving Identified Lives
Authors: Gilbertson Eric 
Published: November 2023

ABSTRACTIn some cases where we are faced with a decision of whether to prioritize identified lives over statistical lives, we have no basis for assigning specific probabilities to possible outcomes. Is there any reason to prioritize either statistical or identified lives in such cases? The ‘uncertainty argument’ purports to show that, provided we embrace ex ante contractualism, we should prioritize saving identified lives in such cases. The argument faces two serious problems. First, it relies on the principle of indifference, and as such it leads to inconsistent assignments of epistemic probability to possible outcomes. Moreover, even if the uncertainty argument can be reformulated in order to avoid reliance on the principle of indifference, the uncertainty in such cases still undermines any judgment of which course of action – saving a statistical, or rather an identified life – involves the greater burden. The indeterminacy involved in the statistical group might be thought to undermine the argument that application of the principle of indifference leads to inconsistency in this case, but the thought that it does rests on a misunderstanding of the relationship between indeterminacy and reference.
MiR‐488‐3p facilitates wound healing through CYP1B1‐mediated Wnt/β‐catenin signaling pathway by targeting MeCP2
Authors: Zuo Chenchen , Fan Pengju , Yang Ying , Hu Chengjun 
Published: November 2023

ABSTRACTIntroductionDiabetic wounds are difficult to heal, but the pathogenesis is unknown. MicroRNAs (miRNAs) are thought to play important roles in wound healing. The effect of miR‐488‐3p in wound healing was studied in this article.Materials and MethodsThe gene methylation was measured by methylation specific PCR (MSP) assay. A dual‐luciferase reporter assay was adopted to analyze the interaction between miR‐488‐3p and MeCP2.ResultsCytochrome P450 1B1 (CYP1B1) is a monooxygenase belonging to the cytochrome P450 family that aids in wound healing. Our findings showed that the miR‐488‐3p and CYP1B1 expression levels were much lower in wound tissues of diabetics with skin defects, but the methyl‐CpG‐binding protein 2 (MeCP2) level was significantly higher than that in control skin tissues. MiR‐488‐3p overexpression increased cell proliferation and migration, as well as HUVEC angiogenesis, while inhibiting apoptosis, according to function experiments. In vitro, MeCP2 inhibited wound healing by acting as a target of miR‐488‐3p. We later discovered that MeCP2 inhibited CYP1B1 expression by enhancing its methylation state. In addition, CYP1B1 knockdown inhibited wound healing. Furthermore, MeCP2 overexpression abolished the promoting effect of miR‐488‐3p on wound healing. It also turned out that CYP1B1 promoted wound healing by activating the Wnt4/β‐catenin pathway. Animal experiments also showed that miR‐488‐3p overexpression could accelerate wound healing in diabetic male SD rats.ConclusionsMiR‐488‐3p is a potential therapeutic target for diabetic wound healing since it improved wound healing by activating the CYP1B1‐mediated Wnt4/‐catenin signaling cascade via MeCP2.