bluuebunny/crossref_metadata_2025_split huggingface dataset:
МОДЕЛЮВАННЯ ОЖИРІННЯ В ЕКСПЕРИМЕНТІ
Authors: Тромбола Олег 
Published: January 2024

Для реалізації поставленої мети було відібрано 135 білих безпородних статевозрілих щурів, з яких сліпим методом було сформовано 2 групи: контрольна (n=15, тварини утримувались на збалансованій дієті) та експериментальна (n=120). Для моделювання ожиріння обрано модель, яка передбачала заміну питної води 60% розчином фруктози в поєднанні із збалансованою дієтою впродовж 8-ми тижнів. При аналізі експериментальної групи на початку моделювання, вага піддослідної тварини складала 132,72±2,45 гр., а після 8 тижнів моделювання - 171,5±10,5 гр, що майже не відрізняється від показників контрольної групи. Індекс маси тіла після 8 тижнів дорівнював 0,49±0,03 гр/см2, індекс Лі - 297,97±11,05 г/см. Критерієм наявності ожиріння в щурів є значення індексу Лі вище 310 г/см, а в результаті проведеного експерименту було отримано дані на рівні 297,97±11,05 г/см, що не дозволило констатувати наявне ожиріння в піддослідних тварин. Було прийняте рішення провести другий етап моделювання шляхом введення в раціон насичених жирів у вигляді свинячого сала в об’ємі 45% від твердих кормів терміном на 8 тижнів. В результаті проведення корекції харчування, середня вага піддослідної тварини на 12 тиждень від початку експерименту зросла до 200,01±19,69 гр, а на 16 тиждень - до 227,62±30,95 гр.; індекс маси тіла на 12 тиждень експерименту складав 0,57±0,04 гр/см2, а на 16 тиждень - 0,65±0,05 гр/см2; індекс Лі на 12 тиждень дорівнював 313,39±10,06 г/см, а на 16 тиждень – 326,85±10,17 г/см.
Моделювання ожиріння шляхом введення в раціон піддослідних тварин насичених жирів у вигляді свинячого сала в об’ємі 45% від твердих кормів та заміни питної води 60% розчином фруктози терміном на 8 тижнів дозволяють викликати ожиріння в 100% піддослідних тварин, оскільки індекс маси тіла складає 0,65±0,05 гр/см2, індекс Лі дорівнює 326,85±10,17 г/см. За підсумками дослідження, для отримання позитивного результату моделювання ожиріння критично важливо правильно обирати хімічну структуру вуглеводного компонента, його кількість і спосіб додавання до дієти та співвідношення із насиченими жирами.
Digital Care Pathway for Patients With Sleep Apnea in Specialized Care: Mixed Methods Study
Authors: Haverinen Jari , Harju Terttu , Mikkonen Hanna , Liljamo Pia , Turpeinen Miia , Reponen Jarmo 
Published: January 2024

Background
Sleep apnea is a significant public health disorder in Finland, with a prevalence of 3.7%. Continuous positive airway pressure (CPAP) therapy is the first-line treatment for moderate or severe sleep apnea. From November 18, 2019, all patients who started their CPAP therapy at Oulu University Hospital were attached to a sleep apnea digital care pathway (SA-DCP) and were instructed on its use. Some patients still did not use the SA-DCP although they had started their CPAP therapy.

Objective
We aimed to study health care professionals’ (HCPs’) perspectives on the SA-DCP and its usefulness for their work; whether the main targets of SA-DCP can be reached: shortening the initial guiding sessions of CPAP therapy, reducing patient calls and contact with HCPs, and improving patients’ adherence to CPAP therapy; and patients’ perspectives on the SA-DCP and its usefulness to them.

Methods
Overall, 6 HCPs were interviewed in May and June 2021. The survey for SA-DCP users (58/91, 64%) and SA-DCP nonusers (33/91, 36%) was conducted in 2 phases: from May to August 2021 and January to June 2022. CPAP device remote monitoring data were collected from SA-DCP users (80/170, 47.1%) and SA-DCP nonusers (90/170, 52.9%) in May 2021. The registered phone call data were collected during 2019, 2020, and 2021. Feedback on the SA-DCP was collected from 446 patients between February and March 2022.

Results
According to HCPs, introducing the SA-DCP had not yet significantly improved their workload and work practices, but it had brought more flexibility in some communication situations. A larger proportion of SA-DCP users familiarized themselves with prior information about CPAP therapy before the initial guiding session than nonusers (43/58, 74% vs 16/33, 49%; P=.02). Some patients still had not received prior information about CPAP therapy; therefore, most of the sessions were carried out according to their needs. According to the patient survey and remote monitoring data of CPAP devices, adherence to CPAP therapy was high for both SA-DCP users and nonusers. The number of patients’ phone calls to HCPs did not decrease during the study. SA-DCP users perceived their abilities to use information and communications technology to be better than nonusers (mean 4.2, SD 0.8 vs mean 3.2, SD 1.2; P<.001).

Conclusions
According to this study, not all the goals set for the introduction of the SA-DCP have been achieved. Despite using the SA-DCP, some patients still wanted to communicate with HCPs by phone. The most significant factors explaining the nonuse of the SA-DCP were lower digital literacy and older age of the patients. In the future, more attention should be paid to these user groups when designing and introducing upcoming digital care pathways.
Psychometric Assessment of an Item Bank for Adaptive Testing on Patient-Reported Experience of Care Environment for Severe Mental Illness: Validation Study
Authors: Fernandes Sara , Brousse Yann , Zendjidjian Xavier , Cano Delphine , Riedberger Jérémie , Llorca Pierre-Michel , Samalin Ludovic , Dassa Daniel , Trichard Christian , Laprevote Vincent , Sauvaget Anne , Abbar Mocrane , Misdrahi David , Berna Fabrice , Lancon Christophe , Coulon Nathalie , El-Hage Wissam , Rozier Pierre-Emmanuel , Benoit Michel , Giordana Bruno , Caqueo-Urízar Alejandra , Yon Dong Keon , Tran Bach , Auquier Pascal , Fond Guillaume , Boyer Laurent 
Published: January 2024

Background
The care environment significantly influences the experiences of patients with severe mental illness and the quality of their care. While a welcoming and stimulating environment enhances patient satisfaction and health outcomes, psychiatric facilities often prioritize staff workflow over patient needs. Addressing these challenges is crucial to improving patient experiences and outcomes in mental health care.

Objective
This study is part of the Patient-Reported Experience Measure for Improving Quality of Care in Mental Health (PREMIUM) project and aims to establish an item bank (PREMIUM-CE) and to develop computerized adaptive tests (CATs) to measure the experience of the care environment of adult patients with schizophrenia, bipolar disorder, or major depressive disorder.

Methods
We performed psychometric analyses including assessments of item response theory (IRT) model assumptions, IRT model fit, differential item functioning (DIF), item bank validity, and CAT simulations.

Results
In this multicenter cross-sectional study, 498 patients were recruited from outpatient and inpatient settings. The final PREMIUM-CE 13-item bank was sufficiently unidimensional (root mean square error of approximation=0.082, 95% CI 0.067-0.097; comparative fit index=0.974; Tucker-Lewis index=0.968) and showed an adequate fit to the IRT model (infit mean square statistic ranging between 0.7 and 1.0). DIF analysis revealed no item biases according to gender, health care settings, diagnosis, or mode of study participation. PREMIUM-CE scores correlated strongly with satisfaction measures (r=0.69-0.78; P<.001) and weakly with quality-of-life measures (r=0.11-0.21; P<.001). CAT simulations showed a strong correlation (r=0.98) between CAT scores and those of the full item bank, and around 79.5% (396/498) of the participants obtained a reliable score with the administration of an average of 7 items.

Conclusions
The PREMIUM-CE item bank and its CAT version have shown excellent psychometric properties, making them reliable measures for evaluating the patient experience of the care environment among adults with severe mental illness in both outpatient and inpatient settings. These measures are a valuable addition to the existing landscape of patient experience assessment, capturing what truly matters to patients and enhancing the understanding of their care experiences.

Trial Registration
ClinicalTrials.gov NCT02491866; https://clinicaltrials.gov/study/NCT02491866
Menggali Kearifan Rasulullah: Landasan Moderasi Beragama dalam Menyelesaikan Konflik
Authors: Shintya Melfa 
Published: January 2024

Unity and cohesion serve as the fundamental pillars for the sustainability and progress of a nation, particularly in the diverse religious landscape of Indonesia. Confronting the complexity of a society with diverse beliefs, religious moderation becomes crucial in maintaining peace and stability. This paper delves into the significance of religious moderation as a foundation for preserving balance between plurality and harmony within a diverse society. The study employs a literature analysis approach, revealing that by referencing the methods employed by Prophet Muhammad in resolving religious conflicts of his time, this research identifies principles of religious moderation adaptable to the current context of Indonesian society. Key steps such as identifying involved parties, facilitating open dialogue, and emphasizing shared values are pivotal in achieving solutions acceptable to all. Drawing wisdom from Prophet Muhammad's approach to religious conflicts, the study concludes that an approach emphasizing equality, respect, and gentle communication serves as valuable guidance in resolving interfaith conflicts.
ABSTRAK
Persatuan dan kesatuan merupakan fondasi utama bagi keberlanjutan dan kemajuan suatu bangsa, khususnya dalam konteks Indonesia yang kaya akan keberagaman agama. Dalam menghadapi kompleksitas masyarakat yang berbeda keyakinan, moderasi beragama menjadi krusial untuk menjaga kedamaian dan stabilitas. Tulisan ini membahas pentingnya moderasi beragama sebagai landasan untuk menjaga keseimbangan antara pluralitas dan harmoni dalam masyarakat yang beragam. Kajian ini menggunakan analisis kepustakaan. Kajian ini menunjukkan bahwa dengan mengacu pada metode yang diterapkan oleh Rasulullah dalam menyelesaikan konflik agama pada zamannya, penelitian ini mengidentifikasi prinsip-prinsip moderasi beragama yang dapat diadaptasi dalam konteks kehidupan masyarakat Indonesia saat ini. Langkah-langkah seperti identifikasi pihak-pihak terlibat, fasilitasi dialog terbuka, dan penekanan pada nilai bersama menjadi kunci dalam mencapai solusi yang dapat diterima oleh semua pihak. Dengan menggali hikmah dari cara Nabi Muhammad menangani konflik agama, penelitian ini menyimpulkan bahwa pendekatan yang menekankan kesetaraan, penghargaan, dan komunikasi yang lembut dapat menjadi pedoman berharga dalam menyelesaikan konflik antar agama.
Characteristics of Charity Cleft Patients in Haulussy General Hospital 2017-2019
Authors: Lilihata Jilvientasia Godive , Irene Jade , Kreshanti Prasetyanugraheni , Van der Meulen Jacques J.N.M , Anggraeni Margareth Ingrid 
Published: January 2024

Cleft lip and palate is a common congenital disorder with an incidence of 1 per 300 live births of Asian descent. There is a lack of cleft epidemiological data due to the absence of plastic surgeons, patients were referred to other provinces or enlisted to charity programs. This paper aims to evaluate the characteristics of our cleft patients at Haulussy General Hospital, Ambon, Maluku from 2017 – 2019. This is a retrospective study of 69 patients treated at Haulussy General Hospital, Ambon, Maluku, charity program from 2017 – 2019. Age, gender, diagnosis, procedure, and nutritional status were collected. 52% of patients are male with a median age of 4 years (range: 3 months – 34 years). The most common diagnosis was complete cleft palate (n=19), and the rarest was microform cleft lip (n=1). Complete cleft lip is more common in males, while isolated cleft palate is more common in females. The median age for primary lip repair, lip revision, and primary palate repair/revision was 1 year, 4.5 years, and 8 years, consecutively. Among 32 patients assessed for nutritional status, 22% were malnourished (19% were underweight, and 3% were severely underweight). Lip repair was done in 28 patients, palate repair in 36 patients, and lip or palate revision in 16 patients. The main techniques used were Lazy S and von Langenbeck.This retrospective study at Haulussy General Hospital from 2017 to 2019 highlights predominant cleft cases and malnutrition among patients. The findings emphasize the importance of tailored interventions and comprehensive care for individuals with cleft lip and/or palate.
Hubungan Terapi Anti-Koagulan dan Status Gizi pada Pasien COVID-19 Derajat Sedang-Berat dengan Mortalitas di Rumah Sakit Sumber Waras, 2021
Authors: Pandapotan Roy Akur , Gunawan Burhan , Andrean Jody , Titus Johana 
Published: January 2024

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) adalah patogen dengan target utama sistem pernapasan dan berhubungan dengan gangguan hiperkoagulasi. Pencegahan insidens trombosis pada pasien COVID-19 dengan obesitas menjadi masalah yang berkaitan dengan efektivitas dan variasi dosis antikoagulan. Tujuan penelitian ini adalah mengetahui hubungan jenis terapi antikoagulan pada pasien COVID-19 derajat sedang-berat yang mengalami status gizi normal dan obesitas dengan mortalitas. Penelitian menggunakan desain retrospektif cross-sectional di Rumah Sakit Sumber Waras, Jakarta Barat pada bulan Januari sampai Juni 2021 pada pasien COVID-19 gejala sedang-berat yang diberikan antikoagulan (unfractioned heparin atau fondaparinux/UFH). Data dianalisis dengan uji chi-square. Jumlah subjek yang dianalisis 152 pasien dengan status gizi terbanyak adalah obesitas 1 (38,82%). Rerata D-dimer subjek obesitas lebih tinggi dari kelompok status gizi normal (2040,61 vs 1955,79 mg/dL). Jumlah subjek yang mendapat heparin dan meninggal adalah 27,3% pada kelompok gizi normal dan 11,1% pada kelompok obesitas. Pada subjek yang mendapat fondaparinuks dan meninggal adalah 31,3% pada kelompok gizi normal dan 15,7% pada kelompok obesitas Tidak terdapat hubungan antara tingkat mortalitas dengan status gizi pada subjek yang mendapat heparin (p=0,08, OR=0,33) maupun fondaparinuks (p=0,17; OR=0,41). Tidak terdapat hubungan antara tingkat mortalitas dengan kondisi obesitas yang mendapat heparin maupun fondaparinuks. Antikoagulan menjadi salah satu manajemen penting untuk penderita COVID-19 dengan obesitas.
“The Great Game” — confrontation between the Anglo-Saxon and Russian world
Authors: Elishev S. O. 
Published: January 2024

This article is devoted to understanding the essence, defining the spatial and time frames, as well as describing the most significant episodes of the development of The Great Game — the policy of containing the development of Russia by Anglo-Saxon elites and powers, dating back more than two centuries. Perceiving Russia as the main obstacle to achieving its global geopolitical hegemony, Anglo-Saxon elites and powers actively waged large-scale diplomatic, economic, information wars and battles against Russia, military operations, conducted operations to organize coups d’etat and “revolutions”, trying to destroy Russia both by actions from outside and undermining it from within. The author of the article draws attention to the origin of the very concept of “Great Game”, as well as its use in a narrow and broad sense. In a narrow sense, this concept is used to denote the active geopolitical and economic confrontation between Great Britain and the Russian Empire for control over Central Asia throughout the 19th century (or according to a number of authors, starting in 1856) until 1907. Broadly, to indicate the global geopolitical confrontation between the Anglo-Saxon and Russian world from thebeginning of the 19th century and continuing to the present.The author believes that the interpretation of the “Great Game” in a narrow sense is incorrect, politically biased and deliberately aimed at hiding the knowledge of the “Great Game” from the mass audience.The author considers various points of view of domestic and foreign authors to determine the starting and final point, time and spatial framework of the “Great Game”. He refers to the vivid episodes of The “Great Game”: the Palace Coup of 1801 — the assassination of Emperor Paul I; “Napoleonic” wars; December putsch of 1825; Confrontation with England in Turkestan, the Caucasus, other regions; Russo-Persian and Russo-Turkish Wars, Crimean War, Russo-Japanese War; the Caucasian War and events in Central Asia and Turkestan; Financing and organization in the Russian Empire of the “fifth column”; Revolutionary events of 1905–1907; World War I; 1917 Revolution; Russian Civil War; Support for “intra-party” opposition; Bringing A. Hitler to power in Germany; World War II organization; “Cold War”, Dismemberment of the USSR; Chechen Wars; “Color revolutions” in the post-Soviet space; The 2008 war and Georgia’s “coercion” to peace; 2014 coup d’état, the subsequent civil war in Ukraine, start of Special Military Operation.
Features of the destructive impact on the youth of the new subjects of the Russian Federation
Authors: Dortseva E. V. , Rodin N. V. 
Published: January 2024

This article is devoted to the study of the peculiarities of the destructive impact on modern Russian youth by foreign states, Russian and international organizations, various groups, with the aim of changing the worldview, value orientations, beliefs, behavioral stereotypes of young people, creating and spreading anti-Russian ideology, forming a negative attitude towards state institutions and traditional values of Russia, as well as undermining socio-economic and political stability in the Russian Federation. Analyzing the examples and features of this kind of influence of these subjects on modern Russian youth, the authors of the article place special emphasis on studying the specifics of this kind of impact on the youth of new subjects of the Russian Federation. To illustrate and substantiate their statements, the authors cite the results of an expert survey “External destructive impact on youth of new constituent entities of the Russian Federation”, conducted in March–April 2023 on the territory of new constituent entities of the Russian Federation among employees of relevant ministries and departments, activists of social movements, specialists in the field of state youth policy in new constituent entities of the Russian Federation (Donetsk People’s Republic and Lugansk People’s Republic).Recognizing the fact of this kind of impact on young people of new constituent entities of the Russian Federation, analyzing the goals of which the subjects of destructive influence, the forms and mechanisms used by them seek, the authors systematize the proposals of experts on countering this impact and improving the mechanisms and forms of implementation of state youth policy in these regions.
Social construction of the health of modern Russianyouth: the main vectors of domestic discourse
Authors: Osipova N. G. 
Published: January 2024

The article presents a systematic analysis of trends and trends in the field of research of health problems in the youth environment, which relate to the attitude to health in general, the field of preserving and strengthening health.The author identifies significant risk factors that significantly affect both the health level of the younger generation and the life expectancy of its representatives, shows the ambivalence and inconsistency of data on the attitude of young people to their health obtained by various researchers. Based on the analysis of various sociological studies, including the author’s study conducted in July 2023, the results of the discussions conducted by domestic scientists addressing the health-saving problems of the younger generation of Russia are summarized.The first group includes macro-social problems related to the general state regulation of public health. Among them are the lack of health care of the population among the state priorities; inadequate social policy of the Russian Federation in the field of healthcare; the activities of institutions included in the management of the health sector, including its regulatory regulation. The second group of problems is related to the conceptualization of the concept of “health” and “healthy lifestyle”, the interpretation of which is usually ambiguous. It is obvious that the normative definition of a “healthy lifestyle” has medical, physiological, psychological and social structural components, which include various external factors — the influence of family and social environment, fashion on social habits, as well as the nature of media exposure.The data obtained by the author indicate that the greatest influence on the formation of young people’s ideas about health problems and practices for its maintenance is exerted by their own experience, social networks, family and the opinion of friends. They also confirm the prevailing trend: although the overwhelming majority of respondents (85%) are sure that people need to lead a healthy lifestyle, one in four believes that their lifestyle is unhealthy rather than healthy, and 5% of them do not consider their lifestyle healthy at all.The author refers to a special group of problems the impact on the health of the digital media environment, into which the younger generation is actively integrated today, first of all, about the so-called “new media”, which include: internet portals of online media, blogosphere, social networks, virtual communities, virtual games and other Web resources. By broadcasting ideas, behavioral models, new media in modern society become “legislators” in various spheres of social life. To a certain extent, they participate in the construction of an individual’s behavior in relation to health, which is both constructive and destructive in nature.
A Study of Student Leadership Development in the Integration of Civic and Psychological Education Based on Social Cognitive Theory
Authors: Wang Qibin , Wang Jingjing 
Published: January 2024

Abstract
Civic and political education and psychological education have a molding effect on students’ leadership, and the developmental study of leadership can better propose cultivation methods. In this paper, for the leadership development of the integration of civic and political education and psychological education, the SCM-LD model is proposed in combination with the social cognitive theory, and the basic assumptions and contents are established. According to the SCM-LD model, evaluation of students’ leadership development was launched by combining social cognitive theory and role theory, and an evaluation index system was constructed. The DEMATEL method was used to construct the causal diagram, which was then used as the foundation for ANP network analysis, and the indicator weights were established through the DANP method. Based on the evaluation method, we will explore the influence of ideological education and psychological education on students’ leadership development. The ANOVA test value of the goal foresight dimension was 0.467, team sharing power was 0.776, and teamwork power was 1.43. In the psychological education course grades, the grades had no significant effect on the leadership level of students, while the grades of the Civic and Political Education course had a certain effect on the leadership level of students. The direction for student leadership development-oriented Civics and Psychoeducation is presented in this study.