bluuebunny/crossref_metadata_2025_split huggingface dataset:
A chimeric vaccine displaying the prM-E proteins of the Australian genotype IV strain of Japanese encephalitis virus protects mice against lethal challenge
Authors: Harrison Jessica J , Nguyen Wilson , Morgan Mahali S , Tang Bing , Haburagira Gervais , de Malmanche Henry , Freney Morgan E , Modhiran Naphak , Watterson Daniel , Cox Abigail L , Yan Kexin , Yuen Nicholas KY , Bowmand Dylan , Kirkland Peter , Bielefeldt-Ohmann Helle , Suhrbier Andreas , Hall Roy A , Rawle Daniel , Hobson-Peters Jody 
Published: November 2023

Abstract
In 2022, a genotype IV (GIV) strain of Japanese encephalitis virus caused an unprecedented and widespread outbreak of disease in pigs and humans in Australia. As no veterinary vaccines against JEV are approved in Australia and all current approved human and veterinary vaccines are derived from genotype (G) III JEV strains, we used the recently described insect-specific Binjari virus (BinJV) chimeric flavivirus vaccine technology to produce a JEV GIV vaccine candidate. Herein we describe the production of a chimeric virus displaying the structural prM and E proteins of a JEV GIV isolate obtained from a stillborn piglet (JEVNSW/22) in the genomic backbone of BinJV (BinJ/JEVNSW/22-prME). BinJ/JEVNSW/22-prME was shown to be antigenically indistinguishable from the JEVNSW/22 parental virus by KD analysis and a panel of JEV-reactive monoclonal antibodies in ELISA. BinJ/JEVNSW/22-prME replicated efficiently in C6/36 cells, reaching titres of 108 infectious units/mL - an important attribute for vaccine manufacture. As expected, BinJ/JEVNSW/22-prME failed to replicate in a variety of vertebrate cells lines. When used to immunise mice, the vaccine induced a potent virus neutralising response against JEVNSW/22 and to GII and GIII JEV strains. The BinJ/JEVNSW/22-prME vaccine provided complete protection against lethal challenge with JEVNSW/22, whilst also providing partial protection against viraemia and disease for the related Murray Valley encephalitis virus. Our results demonstrate that BinJ/JEVNSW/22-prME is a promising vaccine candidate against JEV.
Effect of sublethal dose imidacloprid treatment of Aromia bungii on its parasitoid, Sclerodermus guani
Authors: Li Shuang , Kong Yujun , Sun Zuoxiang , Cao Dandan , Peng Xinyi , Luo Jiayu , Li Jia , Wei Jianrong 
Published: November 2023

Abstract
Aromia bungii Faldermann is an important economic wood borer infested many fruits and ornamental tree in Rosacea family, and is listed as a world quarantine pest. Both chemical and biological control methods have been used to control its damage, but what is their interact effect is unknown.
【Objective】To figure out whether sublethal imidacloprid stimulate the physical and biochemical response of A. bungii larvae so to affect the parasitism rate and offspring development of its parasitoids Sclerodermus guani.
【Method】We detected the activity of detoxification and defense enzymes in the A. bungii larvae treated with sublethal dose of imidacloprid, and investigated its effects on the S. guani. Firstly, LC10, LC20, and LC30 of the imidacloprid were tested to determine the sublethal dose. Then the larvae were treated with the sublethal dose of imidacloprid with artificial diet.
【Result】The sublethal imidacloprid can induce the activity of GST enzyme and inhibition of the CarE activity in A. bungii larvae; the activity of CAT, SOD and POD enzymes was induced and there is a dose effect; the developmental duration of S. guani was not significantly affected, but the parasitism rate, fecundity, the emergence rate and the mortality rate were seriously affected compared with the control.
【Conclusion】The sublethal dose of imidacloprid can induce the strong physical and biochemical response of A. bungii larvae, and had a significant impact on the parasitism success rate and fecundity of S. guani. The results could help us to rational use of insecticides to collaborative with the biological control of the A. bungii with parasitoid.
THM Model of Rock Tunnels in Cold Regions and Numerical Simulation
Authors: Liu Naifei , Liang Shihao , Wang Shuangjie , Song Zhanping 
Published: November 2023

Abstract
The freezing damage of rock tunnels in cold region involves ice-water phase change and complicated interaction of moisture field, temperature field and stress field. Taking the fractured rock mass of cold region tunnels as research subject, the Thermo-Hydro-Mechanical (THM) coupling model of cold region tunnels was established based on the seepage mechanics, heat transfer theory, damage mechanics and equivalent continuum theory. This model could reflect the anisotropic properties of deformation, water migration and heat transfer caused by the initial fracture. The construction and operation processes of a rock tunnel in cold region were simulated, and results were compared with the measured value and predecessor’s achievements. It shows that proposed model could reflect the anisotropic property of surrounding rock and the simulated deformation and stress are not symmetrical. The results of this paper are much closer to the measured value. The insulating layer has a significant effect on the stress of the supporting structures. The maximum tension stress of the lining is 4.5 times as that without insulating layer, and the lining will be destroyed for the overlarge tension stress.
REGIS: Refining Generated Videos via Iterative Stylistic Redesigning
Authors: Abohwo Jason 
Published: November 2023

Abstract
In recent years, generative models have made impressive advancements towards realistic output; in particular, models working in the modalities of text and audio have reached a level of quality at which generated text or audio cannot be easily distinguished from real text or audio Despite these revolutionary advancements, the synthesis of realistic and temporally consistent videos is still in its inception. In this paper, we introduce a novel approach to the creation of realistic videos that focuses on improving the generated video in the latter steps of a video generation process. Specifically, we propose a framework for the iterative refinement of generated videos through repeated passes through a neural network trained to model the spatio-temporal dependencies found in real videos. Through our experiments, we demonstrate that our proposed approach significantly improves upon the generations of text-to-video models and achieves state-of-the-art results of the UCF-101 benchmark; removing the spatio-temporal artifacts and noise that make synthetic videos distinguishable from real videos. In addition, we discuss the ways in which one might augment this framework to achieve better performance.
The Simons Observatory: Development and Optical Evaluation of Achromatic Half-wave Plates
Authors: Sugiyama Junna , Terasaki Tomoki , Sakaguri Kana , Bixler Bryce , Sakurai Yuki , Arnold Kam , Datta Rahul , Galitzki Nicholas , Hasegawa Masaya , Johnson Bradley R. , Keating Brian , Kusaka Akito , Lee Adrian , Matsumura Tomotake , Silva-Feaver Maximiliano , Wang Yuhan , Yamada Kyohei 
Published: November 2023

Abstract
The Simons Observatory (SO) experiment is a cosmic microwave background (CMB) experiment located in the Atacama Desert, Chile. The SO’s small aperture telescopes (SATs) consist of three telescopes designed for precise CMB polarimetry at large angular scales. Each SAT uses a cryogenic rotating half-wave plate (HWP) as a polarization modulator to mitigate atmospheric 1/f noise and other systematics. To realize efficient polarization modulation over the observation bands, we fabricated an achromatic HWP (AHWP) consisting of three sapphire plates with anti-reflection coatings. The AHWP is designed to have broadband modulation efficiency and transmittance. This paper reports on the design and the preliminary characterization of the AHWPs for SATs.
Investigating the Link Between Anxiety and Multiple Sclerosis: A Review
Authors: Mohammed Eiman M. A. 
Published: November 2023

Abstract
Background
Nearly one billion people worldwide have a mental disorder. During the last few years, the number of people suffering from psychological disorders such as depression and anxiety has increased by more than 25%. Just over 22% of multiple sclerosis (MS) patients experience anxiety. MS is an autoimmune disorder of the central nervous system (CNS) that is characterized by a complex interplay of factors, leading to inflammation, demyelination, and neurodegeneration. The disease strikes more people every year with no definitive aetiology. Many genetic, infectious, and environmental factors were confirmed as MS risk factors, but no psychological factors have been considered.
Objective
This review aims to explore the effect of anxiety on the manifestation of MS, the correlation between anxiety and MS symptomology, and possible connection points between anxiety and MS.
Method
A literature search was conducted in the NCBI PubMed database to investigate the impact of anxiety on MS symptomology and episodes, as well as any possible link between anxiety and MS. The search was conducted up to October 2022.
Results
Database searches retrieved a total of 1,607 articles for the phrase ‘multiple sclerosis and anxiety’ published from 1964 to 2022. Data were thoroughly reviewed to include only statistically significant associations. Several articles reported strong associations between anxiety and MS symptoms and episodes. Despite the lack of articles exploring the relationship between anxiety and MS, several pointed to the negative effect of anxiety on the immune system. The fact that MS is an autoimmune disorder of the CNS, and that anxiety dysregulates immunity, could indicate that anxiety has an effect on MS.
Prospective:
Further studies must be undertaken to understand the influence of anxiety on MS; meanwhile, psychological evaluation of MS patients is strongly recommended and needs to be incorporated into treatment plans.
A critical review of multicriteria decision analysis practices in planning of urban green spaces and nature-based solutions
Authors: Bousquet Morgane , Kuller Martijn , Lacroix Sandrine , Vanrolleghem Peter A. 
Published: November 2023

Abstract
Green spaces and nature-based solutions (NBS) are increasingly considered by land-use planning policies to respond to the multiple challenges related to sustainable development. The multiple benefits brought by NBS make the use of multicriteria decision analysis (MCDA) essential to optimally balance their use. MCDA offers a catalog of methods allowing to structure problems with multiple objectives and to help adopt the optimal solution. However, NBS planning is a recent discipline and research is still ongoing to make this practice more common. We carried out a critical literature review on MCDA-NBS tools and practices, following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) method on the Web of Science database. We selected 124 papers on the subject between 2000 and 2022. We present a state-of-the-art MCDA approach for NBS and green space planning by looking at where these practices are applied, why and how this process is conducted, and who is involved in it. We found that studies are usually conducted in the global North on a single case study with the help of experts involved in the criteria weighting phase and the help of GIS MCDA tools often integrating a direct ranking method or the AHP method.
Numerical Study on Discrete Confinement of Circular RC Column Subjected to Eccentric Load
Authors: Yansiku Sandy I. , Piscesa Bambang , Suprobo Priyo 
Published: November 2023

Background:
The performance of concrete-filled steel-tube (CFST) columns under axial compression is excellent. However, the steel-tube wall's instability due to insufficient outward restraint from the concrete made the steel tube lose its lateral support, thereby making it more susceptible to buckling.

Objective:
This study aims to propose and investigate a confinement mechanism that can remove the possibility of buckling of the steel tube by introducing gaps and pre-tension to prevent tube detachment from concrete. The investigation was carried out using both experimental tests and numerical simulation.

Methods:
The proposed confinement mechanism consists of thin steel sheets with gaps between them and is pre-tensioned in a staggered scheme. The performance of the proposed confinement mechanism is evaluated through experimental tests and numerical simulations using an in-house 3D-NLFEA package. The observed behaviors are the axial stress-strain, strength index, initial confining pressure, and ductility.

Results:
Experimental works found that the primary failure mode in the compression zone of the strengthened column was due to lateral expansion of concrete which may be attributed to strain localization, longitudinal tensile cracking, and severe concrete crushing. On the other hand, at the tensile region, pure tensile forces occurred, followed by crack opening displacement at the outer tensile fiber region. With the proposed confinement mechanism, the extreme failure event can be reduced. The axial capacity and ductility of the strengthened column were enhanced. The numerical model presented the initial confining pressure by the pre-tensioned steel sheet (a clamping mechanism), which successfully increased the axial load capacity of the slender reinforced concrete (RC) column and reduced the possibility of cover spalling.

Conclusion:
The proposed confinement mechanism to strengthen an RC column was found to successfully enhance the load-carrying capacity and ductility of a slender circular reinforced concrete column.
Nocardia Lymphadenitis and Encephalitis in Immunocompromised Patient: A Case Report
Authors: Pinzon Rizaldy Taslim , Primastuti Tillandsia Filli Folia 
Published: November 2023

Background:
Nocardiosis-related HIV usually appears in immunocompromised patients, which is caused by Nocardia sp. Although a number of reports describe pulmonary forms of nocardiosis in HIV-positive patients, lymphadenitis and encephalitis due to this organism are rare entities. Our preliminary search has only found a few cases reported in the literature. Unless investigations like gram stain and culture for Nocardia are specifically done, the infection is often mistaken for tuberculosis. We have herein reported a case of Nocardia lymphadenitis and encephalitis in an HIV-positive patient.

Case Presentation:
A 33-year-old male presented fever, progressive weakness in the right side of the body, multiple lesions on the oral cavity, and left colli lesions. Physical examination found GCS as E4 M6 V uncounted, hypertonic and increased physiology reflexes on the right extremity without pathologic reflexes, meningeal signs, and all cranial nerves as normal. The laboratory test result was HIV-positive with CD4+ 7 cells/μL and Nocardia sp. on histopathology. A plain head computed tomography (CT) scan showed a hypodense lesion in the fronto-temporo-parieto-occipital sinistra region, and vasogenic edema. The patient was administered antiretroviral (ARV) therapy and antibiotics for nocardiosis lymphadenitis.

Conclusion:
A rare case of Nocardia lymphadenitis has been reported in this paper, and the physician must be aware of nocardiosis in HIV patients with neurological deficits.
Effect of ER: YAG Laser Treatment on the Bond Strength of Self-adhesive Resin Cements on Contaminated and Non-contaminated Dentin Surface
Authors: Rafeie Niyousha , Rashidi Marie , Chiniforush Nasim , Valizadeh Sara , Omrani Ladan Ranjbar 
Published: November 2023

Background:
Nowadays, lasers are used to modify the surface of dentin and enamel and improve the surface bond with resin cement while contamination weakens this bond.

Objective:
This study aimed to evaluate the effect of different contamination types on the microshear bond strength (μSBS) of two self-adhesive resin cements to dentin with/without laser treatment.

Methods:
One-hundred and twenty molar teeth were prepared and randomly divided into three groups: blood, saliva, and control. In the blood group, blood was applied to the samples for 10 seconds; in the saliva group, saliva was applied to the samples for 10 seconds; and in the control group, distilled water was applied to the samples. Each group was further divided into two subgroups; in one, the Er: YAG laser was applied to samples for 5 seconds, and in the other, no laser treatment was performed. Next, TheraCem and Embrace WetBond cements were placed on each sample. μSBS was measured using a universal testing machine.

Results:
In Embrace WetBond, μSBS was not affected by contamination type regardless of laser treatment. In TheraCem, μSBS was not affected by contamination type when the laser was not used. In contrast, with laser treatment, blood contamination decreased μSBS compared to control and saliva. After laser treatment in the presence of blood, μSBS of Embrace WetBond was significantly higher than that of TheraCem, while without laser treatment, no significant difference was observed between the two cements.

Conclusion:
Dentin conditioning with an erbium laser can increase the cement bond strength to dentin if proper isolation is achievable. If proper isolation cannot be obtained, dentin conditioning with erbium laser followed by application of Embrace WetBond cement can increase the microshear bond strength of cement to dentin.
Management of Trauma-induced External Root Cervical Resorption and Discolouration of the Maxillary Central Incisors: A Case Report with a Four-year Follow-up
Authors: AL-Rawas Matheel , Al-Jobory Ahmed I. , Alang Nur Awanis binti Mohamed , Jamil Wan Ahmad Faiz Wan , Ghani Huwaina Abd , Noorani Tahir Yusuf 
Published: November 2023

Background:
Clinicians often face a dilemma when determining the cause of a patient's tooth discolouration and how to treat it concurrently in the presence of trauma-induced external root cervical resorption.

Objective:
This case report describes the management of trauma-induced cervical resorption and discolouration of the maxillary central incisors with a four-year follow-up.

Case Report:
A 38-year-old gentleman requested that the shape and colour of his anterior teeth be restored. The patient had a history of a motorcycle accident 15 years ago, in 2003, that resulted in fractures in both maxillary central incisors. Clinical examination showed the presence of discoloured broken teeth 11 and 21, as well as a cervical defect in tooth 11 palatally. Upon radiographic examination, 11 and 21 were root canal treated, and there was cervical resorption related to 11. Treatment consisted of cervical resorption management, internal and external bleaching, and composite restoration of the maxillary central incisors.
After a four-year follow-up, this report demonstrated the successful management of a complicated case involving trauma induced resorption and discolouration. The patient expressed satisfaction with the conservative strategy that was taken to treat his discoloured teeth.

Conclusion:
This clinical report, with a long follow-up record, helps to provide dental practitioners with a conservative, minimally invasive, patient-centred treatment alternative for a complicated tooth discoloration case.
HIV/AIDS Risky Behavior Model for LGBT Youth in the Gorontalo Province
Authors: Irwan Irwan , Boekoesoe Lintje , Katili Deliyana I. , Pratiwi Hantulu Desiana , Una Mar’atuljannah 
Published: November 2023

Context:
The behavior model for preventing HIV/AIDS transmission in lesbian, gay, bisexual, and transgender (LGBT) youth can contain HIV/AIDS information in this population.

Objective:
According to Planned Behavior Theory (PBT), human growth within different social environments may gain further information on various issues. This information can be the basis of their behavioral beliefs, social demands of essential others (normative beliefs), and obstacles that can prevent them from showing certain behaviors (control beliefs). These factors can influence intention and behavior. This study aims to develop a model for HIV/AIDS risk-related behavior among LGBT youth based on PBT.

Methods:
This was an observational study using a cross-sectional approach. The modeling used the Structural Equation Model (SEM) pathway through the AMOS 8.50 software application. The variables in this study are internal factors, such as religious obedience, knowledge, beliefs, intention, and risky behavior.

Participants:
This study occurred in Gorontalo Province with 200 LGBT youths with risky behaviors.

Results:
Risk behavior modeling results of LGBT youths in Gorontalo; Religious adherence affects risk behavior through intention. Overall, research results from the study using the PBT approach emphasize that religious obedience does not directly affect the behavioral variables but rather beliefs and intentions.

Conclusion:
HIV/AIDS prevention programs for LGBT youth should focus on religious activities.
The performance of Strengthened Lightweight RC Beams with different Techniques upon Exposure to Fire
Authors: Motawa Yasser , Shoeib Ata El-Kareim , Riad Magdy Youssef , Hassanien Amal 
Published: November 2023

Introduction:
Reinforced concrete beams are used in a wide range of applications. In addition, reducing the weight of the concrete used increases the advantages of the beams. The main objective of this work is to study the performance of structurally strengthened lightweight reinforced concrete beams with different techniques with or without exposure to fire under concentric load and the efficacy of the fire protection system.

Methods:
The experimental specimens included eight half-scale tested rectangle beams with typical dimensions of 300 mm depth, 1700 mm total length, 150 mm total width, 50 mm cover, and 1500 mm span. The density of the lightweight polystyrene foam concrete was 1820kg/m3. The main parameters were fire resistance, different types of strengthening material for lightweight concrete beams, shape of the ferrocement layer on the lightweight concrete surface, and ferrocement thickness.

Results:
The results were analyzed in terms of crack patterns, failure modes, load deflection, load-strain behavior, stiffness, ductility, deformability, and absorbed energy.

Conclusion:
From the analysis of the results, the strength of LWC beams increased the strength and stiffness of the tested beam, and the fire protection system was found effective in protecting CFRP limitation from deterioration. In a theoretical study, the conservatism degree for calculating the maximum allowable flexure force was evaluated according to the ECP203, ACI-318, and BS-8110 codes.
Dinámicas de la tradición oral oaxaqueña: “El mito del pez dorado” y el descubrimiento del Tesoro de Monte Albán
Authors: Mesinas Nicolás Miguel Ángel 
Published: November 2023

El objetivo del presente artículo es enriquecer la difusión y acceso al patrimonio cultural albergado en el Museo de las Culturas de Oaxaca a partir de una investigación basada en la teoría crítica de la Escuela de Frankfurt, con la que se examinó un hecho concreto: el descubrimiento del Tesoro de la Tumba 7 en Monte Albán. Este enfoque proporciona nueva información sobre el pensamiento colectivo que impregnaba la sociedad oaxaqueña en 1932.
Se revisaron relatos, mitos y fábulas que surgieron como consecuencia del Tesoro de Monte Albán; además surgieron resultados interesantes al revisar un mito antiguo conocido como el “pez dorado” y se descubrió cómo se modificó para dar un significado actual a dicho evento, publicado en los periódicos estadounidenses.