bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of a multidisciplinary team approach on the management of diabetic foot ulcers on the Central Coast: A review of the Gosford Hospital High‐Risk Foot Clinic
Authors: Macfarlane Stephanie Mae , Zhao Sarina Xinyan , Lafrenz Jane Olivia , Nagaratnam Manisha Vanya , Tchen Adrian , Linton Clare Elizabeth , Yuen Lili 
Published: January 2024

AbstractThis retrospective cohort study aims to assess whether the implementation of a multidisciplinary approach in the Gosford Hospital High‐Risk Foot Clinic improved outcomes of diabetic foot ulcers. Ulceration is a common foot complication of diabetes mellitus and greatly increases patient morbidity and mortality. Patients who attended at least one appointment at the Gosford Hospital High‐Risk Foot Clinic in 2017 or 2019 were identified through the Gosford Hospital Podiatry department's records. The 2017 and 2019 cohorts were compared on measures of ulcer healing, incidence of amputation, incidence of vascular intervention and surgical debridement, percentage of patients admitted to hospital due to complications and use of systemic antibiotic therapy. Sixty‐one patients in 2017 and 59 patients in 2019 met inclusion criteria, and from them, 207 ulcers were included. Between 2017 and 2019, there was a 6.2‐week reduction in time to 100% ulcer healing in 2019 (p = 0.021), and 10.1% more ulcers healed within 52 weeks (p = 0.22, 95% confidence interval [CI] [−5.9%, 25.5%]). Whilst there was no significant difference in incidence of patients receiving amputation, there was an increased absolute number of amputations in 2019. Implementation of a multidisciplinary approach at the Gosford Hospital High‐Risk Foot Clinic led to improvements in diabetic foot ulcer healing.
Lightweight corundum–spinel ladle wear lining castable with low thermal conductivity
Authors: Wei Jianwen , Guo Yulong , Fu Lvping , Zhang Han , Xu Yexing , Gu Huazhi 
Published: January 2024

AbstractDesigning a lightweight wear‐lining refractory is of great significance for energy savings and consumption reduction. In this study, an in‐house manufactured porous alumina aggregate was selected to replace the commercial tabular alumina aggregate to prepare lightweight corundum–spinel castable (LCSC) for ladle linings. The effect of the porous alumina aggregate on the properties of the corundum–spinel castable was investigated. Compared to tabular alumina, porous alumina possesses higher closed porosity (12.1%) and a small pore size (4.25 µm). The thermal conductivity of LCSC is 21.5% lower than that of dense castable at 1000°C. Owing to the existence of micropores in the porous alumina, the fabricated corundum–spinel castable showed an improved degree of bonding between the aggregate and matrix. Therefore, the lightweight castable showed higher flexural strength and considerable slag corrosion resistance than the dense castable.
Estimation of additive and maternal covariance of production traits in Murrah buffalo
Authors: Sharma Smriti , Dhaka Surender Singh , Patil Chandrashekhar Santosh 
Published: January 2024

AbstractThe study was done to determine additive, maternal and common permanent environmental effects and best‐suited model for some production traits using six univariate animal models that differed in the (co)variance components fitted to assess the importance of maternal effect using likelihood ratio test in Murrah buffaloes. Data from 614 Murrah buffaloes related to production traits were collected from history pedigree sheets maintained at the buffalo farm, Department of Livestock Production and Management (LPM), LUVAS, Hisar. The production traits under this study were 305 days milk yield (305DMY), peak yield (PY), lactation length (LL), dry period (DP), lactation milk yield (LMY) and wet average (WA). The heritability estimates were in the range of 0.33–0.44 for 305DMY, 0.25–0.51 for PY, 0.05–0.13 for LL, 0.03–0.23 for DP, 0.17–0.40 for LMY and 0.37–0.66 for WA. Model 1 was considered best for most of the traits, viz., 305DMY, PY, LL, LMY and WA followed by model 2 for DP. Covariance and correlated values within the traits caused inflation of heritability in model 3 and model 6. The maximum covariance between the additive and maternal effect was found in trait LMY, which was 14,183.90 in model 3 and the minimum value was also reported in the same trait for model 6, valued at −3522.37. Multivariate analysis showed that all production traits were moderate to high and positively correlated with each other except for DP, which was low and negative genetic and phenotypic correlated. Spearman's rank correlation coefficients of breeding value among all six models were high and significant, ranged from 0.78 to 1.00 for all the traits except DP, therefore any of the models could be taken into account depending upon the availability of data.
Timing implant provisionalization: Decision‐making and systematic workflow
Authors: Esquivel Jonathan , Gomez Meda Ramon , Villarroel Milko 
Published: January 2024

AbstractObjectiveProvisionalization is an important step to achieve esthetic results in implant cases, and many different techniques for provisional restoration fabrication have been described. However, depending on the clinical scenario, the provisionalization strategy will require different approaches and timing. The clinician should modify the provisional restorations efficiently to reduce the number of disconnections from the implant, as repeated disconnections may have biological consequences. This article aims to schematize different scenarios requiring implant provisionalization and propose strategies to help the clinician condition the peri‐implant tissues, respecting perio‐prosthodontic fundamentals for soft tissue, biological, and esthetic stability.Clinical ConsiderationsThe clinical outcomes of modern implant therapy aim to achieve results that emulate natural dentition. Different scenarios may require adjunct therapy, including hard‐ and soft‐tissue grafting, which complicates treatment. The provisionalization strategy will vary depending on the initial condition of the tissues, the need for reconstructive procedures, and the timing of implant placement. Selecting the right strategy based on the case type is necessary to reduce treatment time and complications associated with inadequate prosthetic handling of the soft tissues.Clinical SignificanceProper emergence profile conditioning through provisional restorations will allow for biologically sound and esthetically pleasing outcomes in implant restorations.
Sex‐specific pleiotropic changes in emotional behavior and alcohol consumption in human α‐synuclein A53T transgenic mice during early adulthood
Authors: Kalinichenko Liubov S. , Kohl Zacharias , Mühle Christiane , Hassan Zurina , Hahn Agnes , Schmitt Eva‐Maria , Macht Kilian , Stoyanov Lyubomir , Moghaddami Schayan , Bilbao Roberto , Eulenburg Volker , Winkler Jürgen , Kornhuber Johannes , Müller Christian P. 
Published: January 2024

AbstractPoint mutations in the α‐synuclein coding gene may lead to the development of Parkinson's disease (PD). PD is often accompanied by other psychiatric conditions, such as anxiety, depression, and drug use disorders, which typically emerge in adulthood. Some of these point mutations, such as SNCA and A30T, have been linked to behavioral effects that are not commonly associated with PD, especially regarding alcohol consumption patterns. In this study, we investigated whether the familial PD point mutation A53T is associated with changes in alcohol consumption behavior and emotional states at ages not yet characterized by α‐synuclein accumulation. The affective and alcohol‐drinking phenotypes remained unaltered in female PDGF‐hA53T‐synuclein‐transgenic (A53T) mice during both early and late adulthood. Brain region‐specific activation of ceramide‐producing enzymes, acid sphingomyelinase (ASM), and neutral sphingomyelinase (NSM), known for their neuroprotective properties, was observed during early adulthood but not in late adulthood. In males, the A53T mutation was linked to a reduction in alcohol consumption in both early and late adulthood. However, male A53T mice displayed increased anxiety‐ and depression‐like behaviors during both early and late adulthood. Enhanced ASM activity in the dorsal mesencephalon and ventral hippocampus may potentially contribute to these adverse behavioral effects of the mutation in males during late adulthood. In summary, the A53T gene mutation was associated with diverse changes in emotional states and alcohol consumption behavior long before the onset of PD, and these effects varied by sex. These alterations in behavior may be linked to changes in brain ceramide metabolism.image
Clinical and laboratory findings in scrub typhus associated Guillain‐Barré syndrome in South Korea
Authors: Yoon Byeol‐A , Kim Sun‐Young , Kim Juhyeon , Seok Jung Im , Seok Jin Myoung , Lee Sukyoon , Kim Jong Kuk , Oh Seong‐il 
Published: January 2024

AbstractBackground and AimsScrub typhus is an endemic disease in the fall season that occurs in a limited number of places known as the Tsutsugamushi Triangle. Peripheral neuropathy is a common complication of scrub typhus. Herein, we encountered several patients with ascending paralysis after scrub typhus infection, who were diagnosed with Guillain‐Barré syndrome (GBS). We aimed to investigate the clinical and laboratory characteristics of patients who developed GBS after scrub typhus.MethodsPatients were retrospectively recruited from six nationwide tertiary centers in South Korea from January 2017 to December 2021. Patients who had been clinically diagnosed with GBS and confirmed to have scrub typhus via laboratory examination and/or the presence of an eschar before the onset of acute limb paralysis were included. The GBS‐associated clinical and electrophysiological characteristics, outcomes, and scrub typhus‐associated features were collected.ResultsOf the seven enrolled patients, six were female and one was male. The median time from scrub typhus infection to the onset of limb weakness was 6 (range: 2–14) days. All patients had eschar on their bodies. Four patients (57.1%) were admitted to the intensive care unit and received artificial ventilation for respiratory distress. At 6 months, the median GBS disability score was 2 (range, 1–4) points.InterpretationPatients with scrub typhus‐associated GBS have a severe clinical presentation and require intensive treatment with additional immunotherapies. Therefore, GBS should be included in the differential diagnosis when peripheral neuropathies develop during scrub typhus treatment. Notably, scrub typhus is associated to GBS.
Understanding family carer experiences and perceptions of engagement in delirium prevention and care for adults in hospital: Qualitative systematic review
Authors: Lee‐Steere Karen , Mudge Alison , Liddle Jacki , Bennett Sally 
Published: January 2024

AbstractAimTo identify, describe and synthesise what is known about family carers' experiences and perspectives of engagement in delirium prevention and care for adults in hospital.DesignSystematic review and synthesis of qualitative evidence.Data SourcesComprehensive literature search within PubMed, CINAHL, EMBASE, Scopus, Cochrane Central and PsycInfo databases to August 2022. Peer reviewed original qualitative research published in English.MethodsData were extracted using Covidence systematic review software. Methodological quality was reviewed against the Critical Appraisal Skills Program (CASP) Qualitative Checklist. Thematic synthesis was used to develop analytical themes. Confidence in the Evidence from Reviews of Qualitative Research (GRADE‐CERQual) framework was applied to findings.ResultsOf 3429 records identified, 29 met criteria for final inclusion. Studies included a range of settings (intensive care, medical and surgical wards) and family carer types (spouse, daughter, parent and friend). Three primary themes Shared Caregiving, Partnership and Support, Communication for Shared Understanding and three cross‐cutting contextual themes Care Transitions, Family Carer Context and Hospital Context were identified. Family carers have mixed experiences of involvement in delirium care and prevention. Family carer engagement in care impacted perceptions of care quality and their own self‐efficacy. Where person‐centred care expectations were not met, some family carers adopted compensatory or care contingency strategies. Information sharing and timely support from hospital staff who understood the carer context supported carer involvement. Supportive physical environments and addressing power imbalances allowed greater engagement.ConclusionFamily carers often wish to be involved in delirium prevention and care, but need to be recognised as individuals, listened to, informed and supported to optimise their contribution.ImpactThe review findings can guide health professional and decision makers to optimise family carer involvement in delirium care programs.Protocol RegistrationPROSPERO [CRD42020221854].ReportingENTREQ.No Patient or Public Contribution.
Mental health nurses' empathy towards consumers with dual diagnosis: A descriptive study
Authors: Anandan Roopalal , Cross Wendy M. , Nguyen Huy , Olasoji Michael 
Published: January 2024

AbstractAimThis study aimed to assess mental health nurses' empathy towards consumers with dual diagnosis in Australian mental health settings. The research question was What is mental health nurses' empathy towards consumers with co‐existing mental health and drug and alcohol problems?Design and MethodsA cross‐sectional survey was carried out to understand mental health nurses' empathy. The convenience sample included 96 mental health nurses from various mental health settings with experience working with consumers with dual diagnosis. We assessed empathy using the Toronto Empathy Questionnaire. We utilised SPSS™ software to analyse both the descriptive data and multiple‐regression.ResultsThe mean empathy score was 47.71 (SD 8.28). The analysis of the association between demographic variables and individual subscales showed an association between the clinical setting and empathy (p = .031) and sympathetic physiological arousal (p = .049). The work sector was associated with sympathetic physiological arousal (p = .045) and conspecific altruism (p = .008). Emotional contagion (β = .98, p < .001), emotional comprehension (β = 1.02, p < .001), sympathetic physiological arousal (β = 1.01, p < .001) and conspecific altruism (β = 10.23, p < .001) predicted mental health nurses' empathy.ConclusionsThis study found that most mental health nurses showed empathy towards consumers with dual diagnosis. Mental health nurses who are more empathetic towards their consumers experience emotional contagion. They understand emotions better, show sympathetic physiological responses and exhibit kind behaviour towards consumers.Implications for the Profession and Patient CareFurther research is required to understand how mental health nurses adapt to consumers' emotional states in different mental health settings. This information can help clinicians make better decisions about care quality for consumers with dual diagnosis.ImpactThis study addressed mental health nurses' empathy towards consumers with dual diagnosis. Mental health nurses showed increased empathy towards consumers with dual diagnosis. The empathy levels vary based on age, clinical setting, work sector and work experience. Mental health nurses' empathy levels were predicted by emotional contagion, emotion comprehension, sympathetic physiological arousal and conspecific altruism. Empathy enhancement among mental health nurses, particularly towards consumers with dual diagnosis, is crucial and should be regarded as a top priority by healthcare leaders and educators.Reporting MethodOutlined by the Consensus‐Based Checklist for Reporting of Survey Studies (CROSS).Patient or Public ContributionNo Patient or Public Contribution.
Interventions based on salutogenesis for older adults: An integrative review
Authors: Guo Chenming , Deng Mengying , Yu Mingming 
Published: January 2024

AbstractAimsTo synthesize the evidence of interventions based on salutogenesis for older adults.BackgroundWith the increasing tendency of global ageing and the progression of ‘healthy ageing’, salutogenesis has been adopted as a framework of health promotion for older adults.DesignAn integrative review following PRISMA guidelines.Data SourcesSeven databases including PubMed, Cochrane Library, Web of Science, Embase, Scopus, PsycINFO and CINAHL Plus were systematically searched on 29 September 2022 and updated on 18 July 2023.ResultsEighteen eligible studies were included in this review. Salutogenic‐based interventions fell into three main categories: dialogue‐based, health education courses based, and goal setting and achievement based. The intervention doses: length ranged from 4 weeks to 2 years, with most (n = 12) within 12 weeks; the duration of each session ranged from 30 to 150 min, with the majority (n = 7) within 1 h; the frequency ranged from five times weekly to three times in 10 months, and in six studies was once a week. Intervention providers were mostly multidisciplinary teams, while in four studies were nurses only. Most of the studies reported that salutogenic‐based interventions could improve older adults' sense of coherence, quality of life, self‐efficacy, self‐management, meaning of life and mental health.ConclusionsThis review synthesized the interventions based on salutogenesis for older adults, including salutogenesis application, intervention and its doses, intervention settings and providers, and intervention effects. Future research on the effectiveness of the intervention, the optimal dose of the intervention and the underlying mechanisms are still necessary to understand salutogenic‐based interventions.No Patient or Public ContributionNot apply as it's a review paper.Relevance to Clinical PracticeSalutogenic‐based intervention is effective for older adults in different scenarios to improve their health outcomes. Nurses play a key role in salutogenic‐based interventional programs and thus should be essential personnel as the intervention provider.
Work–family conflict among primary health workers during the COVID‐19 pandemic: Its mediating role in the relationship between workload and job burnout
Authors: Wang Jianyun , Zhao Shichao , Tong Xiyang , Wang Minghui , Wang Yiying 
Published: January 2024

AbstractAims and ObjectivesThis study explores the situation of workload, work–family conflict and job burnout among primary health workers in China in the context of COVID‐19 and identifies the mediating effect of work–family conflict between workload and job burnout.BackgroundSince the breakout of the COVID‐19 pandemic, primary health workers have been working on the frontline of the epidemic and may experience increasing workload, work–family conflict and job burnout. It is important to focus on the issue of how to alleviate job burnout of primary health workers.DesignA cross‐sectional study (STROBE) was used.MethodsData were collected from 785 primary health workers in China. Multiple regression analysis was used to examine the mediating effect of work–family conflict between workload and job burnout.Results18.7%, 10.4% and 39.5% of respondents had high job burnout in the dimensions of emotional exhaustion, depersonalization and personal accomplishment, respectively. 34.6% of the respondents had high or very high workload, and 12.8% of the respondents had high or very high work–family conflict. Results of multiple regression analysis indicated that work–family conflict mediated the relationship between workload and job burnout. Workload (β = .163, CI = .207–.549) and work–family conflict (β = .211, CI = .311–.640) positively influenced job burnout, and workload (β = .428, CI = .375–.508) positively influenced work–family conflict.ConclusionThe study indicated that primary health workers experienced a high level of job burnout, especially in the personal accomplishment dimension. Furthermore, this study verified the mediating effect of work–family conflict between workload and job burnout.Relevance to Clinical PracticeSome interventions for alleviating workload, work–family conflict and job burnout should be taken, including workplace assistance programmes, family‐friendly policies and a well‐integrated healthcare system.No Patient or Public ContributionThis study does not involve patient or public contribution in any part.Impact StatementNurses and other primary health workers are health gatekeepers of residents and play a vital role in the healthcare system. Due to the breakout of COVID‐19, they have taken more work and are more vulnerable to work overload, work–family conflict and the consequent job burnout. Some interventions should be taken to effectively alleviate their job burnout and improve their health and performance.
Consensus on the content of an instrument to measure person‐centred teamwork: An e‐Delphi study
Authors: Viljoen Alida , Leech Ronell , Heyns Tanya 
Published: January 2024

AbstractAims and ObjectivesTo establish consensus on items to be included in an instrument to measure person‐centred teamwork in a hospital setting. The objective was to identify the items through a methodological literature review. Refine the items and obtain consensus on the items.BackgroundA definition and related attributes of person‐centred teamwork have been agreed upon. An instrument is needed to measure and monitor person‐centred teamwork in hospital settings.DesignConsensus, electronic Delphi design.MethodsItems were identified through a methodological literature review. These items were included in three electronic Delphi rounds. Using purposive and snowball sampling, 16 international experts on person‐centred care, teamwork and/or instrument development were invited to participate in three electronic Delphi rounds via Google Forms. Descriptive statistics were used to demonstrate their agreement on the relevance and clarity of each item. Items were included if consensus was 0.75. Content analysis was used to analyse written feedback from experts.ResultsThe response rate was 56% (n = 9/16). Nine experts participated over an 8‐week period to reach consensus on the items to be included in an instrument to measure person‐centred teamwork in hospital settings. The experts' responses and suggestions for rephrasing, removing and adding items were incorporated into each round.ConclusionA Delphi consensus exercise was completed, and experts reached agreement on 38 items to be included in an instrument that can be used to evaluate person‐centred teamwork in hospital settings.Relevance to clinical practiceWe engaged with nine international experts in the academic and clinical field of person‐centeredness, teamwork and/or instrument development. An online platform was used to allow the experts to give input into the study. The experts engaged from their own environment with full autonomy and anonymity. Person‐centred teamwork, aimed at improving practice is now measurable. Person‐centred teams improve outcomes of patients. Person‐centred teamwork was specifically developed to assist low compliance areas in hospitals.