bluuebunny/crossref_metadata_2025_split huggingface dataset:
TERAPI DOODLE ART DALAM UPAYA PENCEGAHAN DEMENSIA VASKULAR
Authors: Hapsari Shindi , Hani Umi , Widiyaningsih Widiyaningsih 
Published: December 2023

Demensia vaskular (vascular dementia/VaD) adalah penyebab demensia terbesar. Insiden gangguan kognitif dan demensia merupakan masalah kesehatan masyarakat yang mendesak, dan penyakit serebrovaskular seperti stroke seringkali menjadi kontributor utama. Doodle art sebagai bagian dari seni dapat menjadi terapi yang memberikan stimulai sensori dan kognitif bagi klien yang mengalami gangguan neurologis seperti cedera otak, strok, dan tumor otak. Penelitian ini bertujuan untuk menilai efektivitas terapi doodle art terhadap fungsi kognitif pada pasien post-stroke di Semarang. Penelitian ini menggunakan rancangan kuantitatif dengan pendekatan quasi-experimental pre dan post-test tanpa kelompok kontrol. Sampel penelitian ini penderita paska stroke setidaknya dalam 1 tahun terakhir, berusia > 25 tahun dan dapat berkomunikasi. Penelitian diawali dengan skrining awal tekanan darah dan kemandirian. Responden mengikuti terapi doodle art dalam empat kali pertemuan. Setelah intervensi, pengukuran fungsi kognitif dilakukan kembali. Statistik univariat diujikan untuk melihat karakteristik dan fungsi kognitif responden sebelum dna setelah perlakuan. Data tidak berdistribusi normal menggunakan uji Shapiro Wilk, sehingga perbedaan fungsi kognitif sebelum dan setelah perlakuan dianalisis menggunakan Wilcoxon. Terapi doodle art secara signifikan meningkatkan fungsi kognitif responden (p<0,05). Doodle art sebagai bagian dari seni dapat menjadi terapi yang memberikan stimulai sensori dan kognitif bagi klien yang mengalami gangguan neurologis. Terapi seni dirancang untuk menstimulasi fungsi sensori dan motorik untuk mengaktifkan bagian dari otak yang mengakibatkan gangguan neurokognitif. Intervensi secara berkelompok melibatkan proses kelompok dalam kemampuan orientasi lingkungan. Terapi doodle art dapat menjadi rekomendasi dalam upaya pencegahan demensia.
Keywords: Demensia Vaskular, Stroke, Terapi Doodle Art
LITERATURE REVIEW: EFEKTIVITAS EARLY WARNING SYSTEM (EWS) TERHADAP RESPON TIME PADA PASIEN DEWASA DI RUMAH SAKIT
Authors: Utaminingsih Sri 
Published: December 2023

Pelaksanaan pengkajian EWS sangat membantu perawat dalam mengidentifikasi penurunan kondisi pasien. EWS digital diharapkan dapat mempersingkat waktu dalam pengelolaan tindak lanjut sehingga kondisi yang mengancam jiwa dapat ditangani lebih cepat atau bahkan dapat dihindari. Tujuan dalam penelitian ini adalah menganalisis efektivitas Sistem Peringatan Dini (EWS) digital terhadap waktu tanggap di rumah sakit. Penelitian ini merupakan studi literatur dengan pendekatan PRISMA dengan pendekatan review jurnal dengan menggunakan metode PICO. Database pencarian yang digunakan adalah Science Direct, Pubmed, DOAJ dan Goole Scholar. Wiley Online Library, Sage, Cochrane dengan mengatakan kunci “Respons” DAN “dewasa” DAN “Sistem Peringatan Dini (EWS)”. Hasil penelitian menunjukkan bahwa dari 141 artikel setelah dilakukan screening terdapat 7 artikel yang sesuai dengan kriteria inklusi yaitu EWS pada pasien dewasa tahun 2018-2021. Sebagian besar artikel yang direview adalah penelitian dengan menggunakan desain penelitian Analytical Cross Sectional Studies sebanyak 4 artikel, desain penelitian cohort study sebanyak 2 artikel dan quasi eksperimen sebanyak 1 artikel. Penilaian artikel menggunakan JBI 2020 dengan hasil 4 artikel dalam kategori cukup, 2 artikel dalam kategori baik dan 1 artikel dalam kategori kurang. Kesimpulan dalam penelitian ini adalah sistem early warning scoring yang lengkap akan berdampak pada waktu respon yang lebih cepat pada kondisi darurat, namun EWS tidak dapat memprediksi mortalitas dan morbiditas.
KEPATUHAN MASYARAKAT NUSA TENGGARA BARAT DALAM MELAKSANAKAN PHYSICAL DISTANCING
Authors: PURQOTI DEWI NUR SUKMA , RUSIANA HARLINA PUTRI , ERNAWATI ERNAWATI , ARIFIN ZAENAL , FATMAWATI BAIQ RULLI 
Published: December 2023

Pandemi COVID-19 memberikan dampak yang signifikan dalam keberlangsungan hidup manusia. Untuk memutus rantai penyebaran virus yang peratama kali hadir di Wuhan China, Pemerintah memberlakukan peraturan seperti phyisical distancing hingga Pembatasan Sosial Berskala besar. Tujuan: Penelitian ini bertujuan untuk mengidentifikasi tingkat kepetuhan masyarakat Nusa Tenggara Barat dalam melaksanakan Physical Distencing. Metode: Penelitian ini merupakan penelitian kuantitatif. Disain penelitian yang bersifat deskriptif dengan pendekatan cross sectional, pengambilan sampel menggunakan teknik purposive sampling, pengumpulan data pada penelitian ini dilakukan secara online yang dimulai tanggal 25-30 April 2020 dengan jumlah responden 315 orang. Hasil: Pada penelitian ini didapatkan Responden paling banyak berusia 20-30 tahun sebanyak 192 orang (61%), jenis kelamin paling banyak adalah perempuan sebanyak 170 orang (54%), pendidikan paling banyak adalah PT sebanyak 202 orang (64,1%), pekerjaan paling banyak adalah pelajar/mahasiswa sebanyak 169 orang (53.7%) dengan Tingkat Kepatuhan dalam melaksanakan physical distencing dalam kategori Patuh sebanyak 167 orang (53%) dan dalam kategori tidak patuh sebanyak 148 orang (47%). Kesimpulan: Masyarakat Nusa Tenggara Barat mayoritas dalam kategori patuh dalam melaksanakan physical distencing.
PENGETAHUAN, SIKAP DAN PERILAKU IBU HAMIL SELAMA PANDEMI COVID-19
Authors: Halifah Elka , Kiftia Mariatul , Darmawati Darmawati , Fitri Aida , Rizkia Mira 
Published: December 2023

Kehamilan adalah suatu proses fisiologi seorang wanita untuk meneruskan keturunan, Tujuan Penelitian ini adalah untuk melihat karakteristik ibu hamil dalam menjalani kehamilannya selama pandemic di aceh barat daya privinsi aceh, metode penelitian : adapun jenis penelitian ini bersifat deskriptif dengan pendekatan cross sectional desain. Sampel pada penelitian ini berjumlah 124 ibu hamil sebagai responden dengan metode pemilihan sampel snowball sampling. Analisa data dilakukan dengan menggunakan uji statistic menggunakan spss, hasil penelitian ini didapatkan domisili ibu hamil aceh barat daya sebesar 86,7%, adanya usia ibu hamil berusia 26 – 30 tahun sebesar 44,3%, tingkat pendidikan tinggi sebesar 47,8%, usia kehamilan mayoritas trimester 2 sebesar 41,6% dengan kunjungan kehamilan mayoritas 2 kali sebesar 40,7%, tingkat pengetahuan tinggi sebesar 70,9%, sikap positif sebesar 61,1% dan perilaku baik sebesar 61,9%. Direkomendasikan kepada tenaga pelayanan kesehatan agar dapat memfasilitasi pelayanan khusus ibu hamil dengan menggunakan media elektronik guna mempermudah kunjungan ibu hamil ke pelayanan kesehatan.
Hubungan Pengetahuan Dengan Sikap Perawat Terhadap Perawatan Menjelang Ajal Pada Pasien Paliatif di Ruang ICU
Authors: Candrasari Kinarsanti Marwa , Sutrisno Sutrisno , Widiyono Widiyono 
Published: December 2023

Perawatan menjelang ajal merupakan bagian dari konsep perawatan paliatif yang bertujuan membantu setiap penderita penyakit kronis untuk hidup sebaik mungkin sampai mereka mati dalam keadaan yang baik dan damai. Diperlukan pengetahuan dan sikap yang baik dari perawat dalam memberikan perawatan menjelang ajal pada pasien paliatif. Tujuan penelitian ini adalah untuk mengetahui hubungan pengetahuan dengan sikap perawat terhadap perawatan menjelang ajal pada pasien paliatif di ruang ICU RSUD dr Soediran Mangun Sumarso Wonogiri. Jenis penelitian deskripsi kolerasi dan pendekatan cross sectional. Sampel penelitian adalah 40 perawat ICU. Teknik pengambilan sampel menggunakan total sampel. Instrumen penelitian menggunakan kuesioner pengetahuan dari Palliative Care quiz for Nurses (PCQN) dan kuesioner sikap menggunakan Frommelt Attitude Toward Care of the Daying Form B (FATCOD-B. Analisis data dengan uji Chi Square. Didapatkan hasil bahwa 13 responden (32,5%) dengan pengetahuan baik, 17 responden (42,5%) pengetahuan cukup dan 10 responden (25%) pengetahuan kurang. Terdapat 21 responden mempunyai sikap positif (52,5%) dan 19 responden (47,5%) mempunyai sikap negatif. Hasil uji Chi Square diperoleh nilai c2= 10,625 dengan signifikansi p = 0,005. Ada hubungan pengetahuan dengan sikap perawat terhadap perawatan menjelang ajal pada pasien paliatif di ruang ICU RSUD dr Soediran Mangun Sumarso Wonogiri.
Gejala Perilaku Alexithymia dan Gejala Kecemasan Sosia Dengan Kecanduan Pengguna Smartphone Pada Mahasiswa Keperawatan S1
Authors: Indriyani Ratih , Supriyadi Supriyadi 
Published: December 2023

Latar Belakang: Penggunaan ponsel pintar atau smartphone diperkirakan akan terus meningkat di Indonesia. Dalam enam tahun sejak 2019, penetrasi smartphone Indonesia meningkat sebesar 25,9 persen. Setelah dilakukan screening pada tanggal 15 Febuari pada mahasiswa semester akhir di dapatkan sebagian besar mahasiswa mengalami kecanduan smartphone hampir 70 persen dari jumlah populasi. Tujuan penelitian untuk mengetahui hubungan gejala alexithymia dan gejala kecemasan sosial dengan kecanduan pengguna smartphone pada mahasiswa tingkat akhir keperawatan S1 Universitas Muhammadiyah Purwokerto. Metode penelitian menggunakan penelitian kuantitatif dengan pendekatan cross sectional. Sampel penelitian adalah Mahasiswa Keperawatan tingkat akhir dengan jumlah 42 responden dengan metode simple rondom sampling pada bulan Febuari-Maret 2023. Instrumen penelitian menggunakan kuesioner dengan uji Chi-Square. Hasil penelitian didapatkan 71,4 persen responden dengan tingkat kecanduan smartphone termasuk kategori tinggi, gejala alexithymia dengan tingkat tinggi sebesar 54,8 persen dan gejala kecemasan sosial tinggi sebesar 42,9 persen. Terdapat hubungan gejala alexithymia dengan kecanduan smartphone (p-value= 0,000) dan terdapat hubungan gejala kecemasan sosial dengan kecanduan smartphone (p- value= 0.003). Kesimpulan pada penelitian ini bahwa tingkat kecanduan, gejala alexithymia dan gejala kecemasan sosial termasuk dalam kategori tinggi sehingga terdapat hubungan antara gejala alexithymia dan gejala kecemasan sosial dengan kecanduan penggunaan smartphone.
Kata Kunci: Gejala Alexithymia, Gejala Kecemasan Sosial, Kecanduan Smartphone.
Computed Tomography Imaging Vessels, Airways and Emphysema: Association With Airflow Limitation in COPD
Authors: Asghar Huma 
Published: December 2023

<p>Parenchyma, airways and vessels are different compartments of the lung affected by chronic obstructive pulmonary disease (COPD). The impact of COPD on the parenchyma, known as emphysema, is characterized by tissue destruction, whereas disease in the airways and vessels manifests itself in terms of inflammation, structural remodelling/pruning. Emphysema has been shown to be associated with pruning of both airways and vessels and conventional measures of vascular remodelling may not be a sensitive measure of pruning/vessel loss because of proximal pruning of vessels resulting in their distal dilation. </p>
<p>Therefore, this work focusses on development of a novel measurement of vascular loss, investigates the association between airway and vessel remodeling/loss and highlights relative contributions of different disease features towards airflow limitation in COPD. </p>
<p>A significant association was found between measurements of airway and vascular pruning with our developed vascular measurement showing strongest association with airway measure, compared to the conventional measures of vascular loss, thus adding to its validity. Vascular alterations, airway remodelling and emphysematous destruction showed strongest relative association with airflow limitation in people who are at risk of developing COPD, mild COPD and moderate-severe COPD, respectively.</p>
The Reasons of Errors That Change The Meaning in The Subject of Holy Quran Memorization from The University Science Islam Malaysia Students’ Perception
Authors: Qatanany Ahmed Abedalqader Hasan , Abdullah Samarh Samer Najeh , Saleh Muhammad Hafiz , Toure Abdoul Karim 
Published: December 2023

This study aims to identify the reasons behind committing errors that change the meaning of the Holy Quran. Various studies revealed that students committed errors that led to changing the intended meaning of holy verse while reciting the Quran orally. Based on this problem, the current study investigates this issue using the descriptive approach. Three hundred fifty-seven questionnaire forms were distributed among students from six colleges out of twelve in the University Sciences Islam Malaysia who have the subject of memorizing the Holy Quran. The questionnaire was divided into four sections. The first three sections included information about students’ levels in memorizing and reciting the Holy Quran in Arabic. At the same time, the fourth section is about the reasons for changing the Holy Quran meaning. SPSS was utilized to analyze the data. The results showed that the students did not appropriately memorize the verses. Furthermore, the students do not master the Arabic alphabetic letters exits. The results indicated that students do not understand Arabic Language adequately. This issue represents the main reason for changing the meaning during the reciting of the Holy Quran. Thus, the study recommends making a video record to treat such causes.
Results of a Teacher Burnout Intervention with Self-compassion and Self-Concordant Goals
Authors: Nagy Eszter , Takács Ildikó 
Published: December 2023

This research aimed to help decrease the level of burnout among Primary School teachers in Hungary. We conducted a 7 week-long "Renewal programme" intervention, which was based on self-compassion theory and the self-concordance model. Self-compassion practices advocate the adoption of an accepting mindset regarding one's own mistakes, and further assume that by setting self-concordant goals, one can create the conditions for long-term intrinsic motivation. Our results showed that the Renewal programme decreased participants' burnout levels. It also turned out that the programme was more effective for those participants who were doing their homework regularly. Self-compassion was a relatively new concept for teachers who participated in the intervention, but 6 months after the programme ended, the levels of it had increased further beyond what was recorded in the post-measurement. Our results show that social support is an important characteristic of the programme, as burnout subsequently decreased, while self-compassion increased, possibly due to the decreasing support of the former group members. As an enhancement, we recommend creating a private social media group for participants, something which would enable future participants to stay in touch after a programme like this has ended.
Carotid plaque score and ischemic stroke risk stratification through a combination of B-mode and contrast-enhanced ultrasound in patients with low and intermediate carotid stenosis
Authors: Li Fang , Gu Shi-Yao , Zhang Lu-Ni , Chen Jing , Yao Ming-Hua , Wu Ting-Ting , Ma Ji , Jia Cai-Xia , Wu Rong 
Published: December 2023

ObjectiveThe occurrence of ischemic stroke (IS) is closely related to the characteristics of carotid plaque (CP). Due to the effect of stroke risk stratification based on B-mode ultrasound (US) and contrast-enhanced ultrasound (CEUS) that has not been studied in patients with low and intermediate carotid stenosis, we construct and validate a CP score and ischemic stroke risk stratification (ISRS) using a combination of B-mode and CEUS, in order to provide new convenient strategies to stratify these patients to prevent stroke.Materials and methodsThis retrospective study evaluated 705 patients with low and intermediate carotid stenosis who underwent B-mode and CEUS from November 2021 to April 2023. Qualitative B-mode and CEUS features of carotid plaques were analyzed using a univariable and multivariable logistic regression to construct the CP score. Then, we combined the CP score with Essen stroke risk score (ESRS) to develop ISRS.ResultsThis study included a total of 705 patients with low and intermediate carotid stenosis, of which 394 were symptomatic patients (with a mean age of 71.03 ± 10.48 years) and 311 were asymptomatic patients (with a mean age of 65.13 ± 10.31 years). Plaque echogenicity, plaque morphology, carotid intima-media thickness in B-mode US and intraplaque neovascularization grading and perfusion pattern in CEUS were significantly associated with IS. The ISRS incorporating these five predictors and ESRS showed good discrimination and calibration in both primary cohort [area under the curve (AUC), 0.91; Hosmer–Lemeshow test, p = 0.903] and validation cohort (AUC, 0.84; Hosmer–Lemeshow test, p = 0.886).ConclusionWe developed an effective and practical tool to identify and stratify patients with low and intermediate carotid stenosis, based on the CP score and ISRS estimation. Our study may provide new insights into managing patients with no indication of surgery.
Global proteomics insights for a novel small compound targeting the non-integrin Laminin Receptor in a macrophage cell model
Authors: Haffner Abigail , Figueiredo Neto Manoel , Umbaugh C. Samuel , Sobreira Tiago J. P. , Lescun Timothy B. , Sintim Herman O. , Figueiredo Marxa L. 
Published: December 2023

Introduction:Monocytes and macrophages are the first barrier of the innate immune system, which interact with agents causing osteoarthritis or other conditions, leading to the release of proinflammatory mediators that exacerbate inflammation.Methods:The aim of this study was to investigate the proteomic changes in THP-1 monocytes differentiated to macrophages, pre- or -post small compound treatments and in the presence or absence of a proinflammatory stimulus, Lipopolysaccharide (LPS). This study aimed to discover and isolate small compounds that mimic the interaction between Pigment derived growth factor (PEDF) and its 37/67 kDa Laminin receptor (LR) with potential anti-inflammatory activity.Results:Our results suggested that novel compounds targeting the LR-PEDF interface can be useful for modulating anti-inflammatory effects. Several compounds were selected based onin silicodocking at the PEDF/LR interface and examined for their ability to reduce IL-1β expression in a macrophage cell model. Compound C3 showed the highest efficacy in reducing IL-1β expression in the presence of LPS proinflammatory stimulus. Proteomics analysis revealed that C3 treatment altered the global proteomic profile of THP-1 activated macrophages, affecting pathways such as MYC targets, oxidative phosphorylation, and mTORC1 signaling.Discussion:The analysis also highlighted the involvement of key regulators, including RPSA and MYC, and their interactions with other proteins such as ribosome proteins and cell cycle regulators. Furthermore, the downregulated proteome analysis revealed shared and unique pathways affected by the treatments, including processes related to actin cytoskeleton, translation, and the inflammatory response. Protein-protein interaction networks suggested the potential involvement of transcription factors like MYC and the interconnectedness of signaling pathways in mediating such as the effects of the treatments. Overall, these findings provide valuable insights into the potential anti-inflammatory activity and underlying mechanisms of compound C3, emphasizing its relevance for further investigation in the context of inflammatory conditions.
Multiparametric ultrasound-based assessment of overt hyperthyroid diffuse thyroid disease
Authors: Stoian Dana , Borlea Andreea , Moisa-Luca Luciana , Paul Corina 
Published: December 2023

IntroductionHyperthyroidismis a prevalent condition affecting global populations, with an overall prevalence of 1.2%. Our research aimed to establish a systematic diagnostic approach using multiparametric ultrasound (MPUS) to diagnose hyperthyroid diffuse thyroid disease (DTD).MethodsWe conducted a retrospective study from June 2021 to June 2023 at a specialized endocrinology center in Timisoara, Romania, enrolling subjects presenting with clinical hyperthyroidism. Using the Mach 30 Aixplorer ultrasound equipment, evaluations were performed initially in B-mode US, followed by Color Doppler and Spectral Doppler measurements, and finally, 2D Shear wave elastography (SWE).ResultsFrom the 218 patients analyzed, the diagnosis of DTD with hyperthyroidism was confirmed through biochemical assessment, subgrouping various pathologies such as subacute thyroiditis, Graves’ disease, painless thyroiditis, Hashimoto’s thyroiditis, iatrogenic, as well as healthy controls. In the first step, B-mode hypoechogenicity had an AUC of 0.951 for DTD detection. In the second step, the peak systolic velocity differentiated Graves’ disease with a median of 42.4 cm/s and an AUC of 1. Lastly, the third step consisted of SWE evaluation, revealing a mean elasticity index in the SAT subgroup significantly higher from other subgroups (p&lt;0.001) with an AUC of 1.ConclusionOur study offers a step-by-step evaluation algorithm for DTD diagnosis, with a very good overall diagnostic performance (AUC of 0.946).
Assessing nitrous oxide emissions and productivity of cropping systems for biogas production using digestate and mineral fertilisation in a coastal marsh site
Authors: Herrmann Antje , Verma Supriya , Techow Anna , Kluß Christof , Dittert Klaus , Quakernack Robert , Pacholski Andreas , Kage Henning , Taube Friedhelm 
Published: December 2023

Significant greenhouse gas emissions during substrate cultivation reduces the potential environmental benefits of biogas production. This study investigates the productivity of different cropping systems and their environmental impact in terms of nitrous oxide (N2O) emissions under the environmental conditions of the coastal marsh regions (Northern Germany) with heavy clay soils, in a 2-year field trial (April 2009-March 2011). Treatments included four cropping systems (perennial ryegrass (Lolium perenne, PR) ley, continuous maize (Zea mays), a rotation (CR1) of spring wheat (Triticum aestivum), Italian ryegrass (Lolium multiflorum, IR) and maize, and a rotation (CR2) of maize, winter wheat and IR; two sources of N (nitrogen) fertilizers (calcium ammonium nitrate, and biogas residue (BR)), and three levels of N fertilizer applications (control, moderate, high). Nitrous oxide emissions were determined for the unfertilized and highly fertilized cropping systems comprising PR ley, CR1 and CR2. Cumulative annual N2O emissions varied across the treatments, ranging from 0.82 to 3.4 kg N2O-N ha−1 year−1. Under high N fertilizer applications, PR ley incurred higher N2O-N losses compared to other tested cropping systems, and IR cover crop caused relatively high N2O-N emissions in a short vegetation period. The study observed wide range of yield-scaled emissions (0.00–5.60 kg N2O-N (Mg DM)−1) for different crops, emphasizing the variability in N2O emissions linked to cropping systems. The N2O-N emission factors for the three cropping systems were found to be low to moderate for all treatments, ranging from 0.03% to 0.53% compared to IPCC default Tier 1 N2O-N EFs. The lower emissions in the study were associated with prolonged high soil moisture conditions (water filled pore space &gt;70%.), indicated by its negative correlation with N2O-N fluxes. Low dry matter and N yield of PR and of the wheat-IR sequence after BR application compared to other crops indicated a low N use efficiency. The estimation of N2O-N emissions based on N surplus was not promising specifically for the coastal study site where high groundwater level and organic matter in the soils were the predominant drivers for N2O-N emissions.