bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evidence for circulation of Rift Valley fever virus in wildlife and domestic animals in a forest environment in Gabon, Central Africa
Authors: Becquart Pierre , Kombila Linda Bohou , Mebaley Telstar Ndong , Paupy Christophe , Garcia Déborah , Nesi Nicolas , Olive Marie-Marie , Vanhomwegen Jessica , Boundenga Larson , Mombo Illich Manfred , Piro-Mégy Camille , Fritz Matthieu , Lenguiya Léadisaelle Hosanna , Gouilh Meriadeg Ar , Leroy Eric M. , N’Dilimabaka Nadine , Cêtre-Sossah Catherine , Maganga Gael Darren 
Published: October 2023

AbstractRift Valley fever (RVF) is a mosquito-borne viral zoonosis caused by the RVF virus (RVFV) that can infect domestic and wild animals. Although the RVFV transmission cycle has been well documented across Africa in savanna ecosystems, little is known about its transmission in tropical rainforest settings, particularly in Central Africa. We therefore conducted a survey in northeastern Gabon to assess RVFV circulation among wild and domestic animals. Among 163 wildlife samples tested using RVFV-specific RT-qPCR, four ruminants belonging to subfamily Cephalophinae were detected positive. The phylogenetic analysis revealed that the four RVFV sequences clustered together with a virus isolated in Namibia within the well-structured Egyptian clade. A cross-sectional survey conducted on sheep, goats and dogs living in villages within the same area determined the IgG RVFV-specific antibody prevalence using cELISA. Out of the 306 small ruminants tested (214 goats, 92 sheep), an overall antibody prevalence of 15.4% (95% CI [11.5–19.9]) was observed with a higher rate in goats than in sheep (20.1%versus3.3%). RVFV-specific antibodies were detected in a single dog out 26 tested. Neither age, sex of domestic animals nor season was found to be significant risk factors of RVFV occurrence. Our findings highlight sylvatic circulation of RVFV for the first time in Gabon. These results stress the need to develop adequate surveillance plan measures to better control the public health threat of RVFV.Author summaryRift Valley fever (RVF) is a mosquito-borne viral zoonosis caused by the RVF virus (RVFV) that can affect wild and domestic animals. Although the RVFV transmission cycle has been well documented across Africa in savanna ecosystems, little is known about its transmission in tropical rainforests, especially in Central Africa. We thus conducted a survey in northeastern Gabon to assess RVFV circulation among wild and domestic animals. In this study, we demonstrated for the first time in Gabon the presence of the RVFV in two wildlife species (Peter’s duikerCephalophus callipygusand the blue duikerPhilantomba monticola). In addition, we detected RVFV-specific antibodies in small domestic ruminants (sheep and goats) with an overall antibody prevalence of 15.4%, with a much higher seroprevalence rate in goats than sheep (20.1% versus 3.3%). Furthermore, RVFV-specific antibodies were also observed in a single (hunting) dog out of the 26 tested. These results stress the need to develop adequate surveillance plan measures to better control the public health threat of RVFV.
Multiple transcription factors mediate acclimation of Chlamydomonas to light stress
Authors: Wulf Donat , Krüger Fabian Janosch , Klages Levin Joe , Viehöver Prisca , Jin EonSeon , Wobbe Lutz , Eisenhut Marion , Kruse Olaf , Blifernez-Klassen Olga , Bräutigam Andrea 
Published: October 2023

AbstractLight as a substrate for photosynthesis may be a boon or a bane. To thrive, photosynthetic organisms must constantly respond to changing light and CO2 conditions by balancing energy harvest and consumption in a highly dynamic way. Two major safeguard measures of photoacclimation, that is photoprotection and carbon concentrating mechanism, underlie tight transcriptional control, leading to expression changes under high light and limited CO2 with different dynamics for both systems. Here, by using a consensus gene regulatory network inferred by employing a compendium of 1,869 RNA-seq datasets, we identified and validatedin vivoeight candidate transcription factors (TFs) that contribute to photoacclimation inChlamydomonas reinhardtii. Target gene analyses indicate that the TFs act individually in associated pathways but also influence each other in expression, and function as network parts with partial redundancy with respect to photoprotection. The analyses unveil that stress responses inChlamydomonasare mediated by a complex, interconnected network of TFs rather than a hierarchical system where multiple regulators can influence each other and target gene expression and thereby mitigate the effects of loss.
Biosynthesis of macrocyclic peptides with C-terminal β-amino-α-keto acid groups by three different metalloenzymes
Authors: Nguyen Dinh T. , Zhu Lingyang , Gray Danielle L. , Woods Toby J. , Padhi Chandrashekhar , Flatt Kristen M. , Mitchell Douglas A. , van der Donk Wilfred A. 
Published: October 2023

AbstractAdvances in genome sequencing and bioinformatics methods have identified a myriad of biosynthetic gene clusters (BGCs) encoding uncharacterized molecules. By mining genomes for BGCs containing a prevalent peptide-binding domain used for the biosynthesis of ribosomally synthesized and post-translationally modified peptides (RiPPs), we uncovered a new class involving modifications installed by a cytochrome P450, a multi-nuclear iron-dependent non-heme oxidative enzyme (MNIO, formerly DUF692), a cobalamin- and radicalS-adenosyl-L-methionine-dependent enzyme (B12-rSAM), and a methyltransferase. All enzymes encoded by the BGC were functionally expressed inBurkholderiasp. FERM BP-3421. Structural characterization with 2D-NMR and Marfey’s method on the resulting RiPP demonstrated that the P450 enzyme catalyzed the formation of a biaryl C-C crosslink between two Tyr residues with the B12-rSAM generating β-methyltyrosine. The MNIO transformed a C-terminal Asp residue into aminopyruvic acid while the methyltransferase acted on the β-carbon of the α-keto acid. Exciton-coupled circular dichroism spectroscopy and microcrystal electron diffraction (MicroED) were used to elucidate the stereochemical configurations of the atropisomer that formed upon biaryl crosslinking. The conserved Cys residue in the precursor peptide was not modified as in all other characterized MNIO-containing BGCs; However, mutational analyses demonstrated that it was essential for the MNIO activity on the C-terminal Asp. To the best of our knowledge, the MNIO featured in this pathway is the first to modify a residue other than Cys. This study underscores the utility of genome mining to discover new macrocyclic RiPPs and that RiPPs remain a significant source of previously undiscovered enzyme chemistry.
SPARK regulates AGC kinases central to theToxoplasma gondiiasexual cycle
Authors: Herneisen Alice L. , Peters Michelle L. , Smithh Tyler A. , Shortt Emily , Lourido Sebastian 
Published: October 2023

ABSTRACTApicomplexan parasites balance proliferation, persistence, and spread in their metazoan hosts. AGC kinases, such as PKG, PKA, and the PDK1 ortholog SPARK, integrate environmental signals to toggle parasites between replicative and motile life stages. Recent studies have cataloged pathways downstream of apicomplexan PKG and PKA; however, less is known about the global integration of AGC kinase signaling cascades. Here, conditional genetics coupled to unbiased proteomics demonstrates that SPARK complexes with an elongin-like protein to regulate the stability of PKA and PKG in the model apicomplexanToxoplasma gondii. Defects attributed to SPARK depletion develop after PKG and PKA are down-regulated. Parasites lacking SPARK differentiate into the chronic form of infection, which may arise from reduced activity of a coccidian-specific PKA ortholog. This work delineates the signaling topology of AGC kinases that together control transitions within the asexual cycle of this important family of parasites.
Orchestration of value: the role of customer success managers within sales ecosystems
Authors: Goad Emily A. , Chase Kevin S. , Brauer David B. , Chefor Ellis , Chaker Nawar N. , Rabago Ruben , Hochstein Bryan , Hansen John D. 
Published: October 2023

Purpose
This study aims to integrate research on customer success (CS) management with the service ecosystems perspective of selling to enhance the understanding of the CS management function and the outcomes selling firms should expect based on implementation of CS management.

Design/methodology/approach
The authors apply the service ecosystems perspective of selling to describe how CS management is manifested in practice by offering relevant insights and practical industry examples.

Findings
Study findings identify relevant ecosystem actors, acting on behalf of the customer, required for the delivery of desirable customer outcomes. Study findings also link the orchestration efforts of CS managers to theory-based tenets for explanation of how CS management facilitates the attainment of competitive advantages via the thickening and thinning of ecosystem crossing points.

Research limitations/implications
Given that the research is conceptual, additional research that empirically examines this framework and the insights presented would lend further credence to the recommendations the authors suggest.

Practical implications
From a practical perspective, the authors present a “Customer Relationship and Solution Innovation Matrix” which integrates necessary value-creating activities that CS managers perform and the coordination with internal actors that CS managers rely on to create value.

Originality/value
Although the practice of CS management is becoming increasingly common, theoretical approaches capable of explaining the function have been lacking. Similarly, while the service ecosystems perspective redefines selling to encompass a broader set of actors than traditionally examined, practical examinations of the theory are limited. The authors address these issues, integrating both research streams for an enhanced understanding of the CS management function through the service ecosystems perspective theoretical lens.
Does inflation expectation affect banks' performances? Evidence from Indian banking sector
Authors: Maria Minnu Baby , Hussain Farah 
Published: October 2023

PurposeThe study intends to evaluate the impact of inflation expectation on the performance of listed commercial banks in India during 2005–2021. Inflation expectation is considered as a direct policy tool by the policymakers for stability of the economy. The study explores how inflation expectation affects the performance indicators of the Indian banking industry while controlling for a wide range of bank-specific factors.Design/methodology/approachThe study applies the generalized method of moments (GMM) on a panel sample of 27 listed bank to analyse the impact of inflation expectation on banking sector performance. The data on inflation expectation are obtained from the household inflation expectation survey introduced in India by the Reserve Bank of India in 2005. Return on assets (ROA), return on equity (ROE) and Tobin's Q have been considered as the banking performance indicators in this study.FindingsEmpirical results exhibit that inflation expectation is instrumental in deciding the banking sector's performance. Inflation expectation has been found to have a significant and positive impact on accounting-based measures of banking performance. At the same time, it shows negative impact on the marketing-based measure.Practical implicationsThe study gives a clear picture about how inflation expectation affects the banking performance and the monetary policy of the country. The study provides crucial insights to develop strategic decisions for the Indian banking sector. The adoption of proper macroeconomic policies, taking into account inflation expectation levels, is instrumental in enhancing bank's performance and in achieving economic growth.Originality/valueThis study contributes to the growing body of literature on the impact of inflationary conditions on banking performance. The originality lies in capturing the role of inflation expectation solely in determining banking sector performance.
Knowledge management and resistance to change as moderators in the relationship between change management and job satisfaction
Authors: Shaik Shamshad Ahamed , Batta Ankaiah , Parayitam Satyanarayana 
Published: October 2023

PurposeThis research aims to explore the effect of change management on job satisfaction. A conceptual model involving knowledge management and resistance to change as moderators tested the relationships in the context of a developing country, India.Design/methodology/approachData from 413 respondents from four important sectors – healthcare, education, manufacturing and information technology – were collected from southern India. First, the psychometric properties of the survey instrument were checked, and then hypotheses were tested using Hayes's PROCESS macros.FindingsThe results indicate that change management significantly predicts employee productivity and job satisfaction. Further, employee productivity mediated the relationship between change management and job satisfaction. This study also found that the resistance to change (first moderator) and knowledge management (second moderator) interacted with change management to enhance employee productivity.Research limitations/implicationsThis study has several contributions to the practitioners and academic scholars. The study has limitations, which are inherent in survey-based research, of common method bias and social desirability bias. However, the authors have taken adequate care to minimize these biases.Originality/valueThe three-way interaction (moderated moderated-mediation) tested in this research uniquely contributes to the literature on change management. To the best of the authors’ knowledge, this moderated moderated-mediation has been tested for the first time in the context of a developing country, India, and provides valuable insights into the practicing managers and change agents in bringing successful change in organizations.
Metaverse-infused academic libraries: a glimpse into the future
Authors: Amzat Omolara Basirat , Adewojo Akinade Adebowale 
Published: October 2023

PurposeThis study aims to explore the transformative potential of integrating artificial intelligence (AI) and the metaverse into academic libraries, envisioning a future where personalized, immersive and accessible user experiences redefine the traditional concept of libraries. The purpose is to analyse the synergy between AI and the metaverse in enhancing library services and user interactions.Design/methodology/approachThe study uses a literature review approach to synthesize current knowledge on AI, the metaverse and their integration into academic libraries. It delves into the functionalities of AI in cataloguing, personalization and predictive analysis, coupled with the immersive experiences offered by the metaverse. The design envisions metaverse-infused academic libraries as digital spaces hosting AI-driven virtual assistants, personalized learning paths and collaborative environments.FindingsThe integration of AI and the metaverse in academic libraries presents opportunities for personalized learning experiences, efficient resource management and global collaboration. The findings suggest that the synergy enhances accessibility, inclusivity and efficiency in library services, albeit with challenges such as the digital divide, privacy concerns and technical complexities.Originality/valueThis study contributes to the discourse on the future of academic libraries by proposing a comprehensive vision of metaverse-infused libraries empowered by AI. It underscores the originality and value of the integration, emphasizing the potential for personalized, interactive and globally accessible learning and research environments.
The utilisation of open research data repositories for storing and sharing research data in higher learning institutions in Tanzania
Authors: Mosha Neema Florence , Ngulube Patrick 
Published: October 2023

PurposeThe study aims to investigate the utilisation of open research data repositories (RDRs) for storing and sharing research data in higher learning institutions (HLIs) in Tanzania.Design/methodology/approachA survey research design was employed to collect data from postgraduate students at the Nelson Mandela African Institution of Science and Technology (NM-AIST) in Arusha, Tanzania. The data were collected and analysed quantitatively and qualitatively. A census sampling technique was employed to select the sample size for this study. The quantitative data were analysed using the Statistical Package for the Social Sciences (SPSS), whilst the qualitative data were analysed thematically.FindingsLess than half of the respondents were aware of and were using open RDRs, including Zenodo, DataVerse, Dryad, OMERO, GitHub and Mendeley data repositories. More than half of the respondents were not willing to share research data and cited a lack of ownership after storing their research data in most of the open RDRs and data security. HILs need to conduct training on using trusted repositories and motivate postgraduate students to utilise open repositories (ORs). The challenges for underutilisation of open RDRs were a lack of policies governing the storage and sharing of research data and grant constraints.Originality/valueResearch data storage and sharing are of great interest to researchers in HILs to inform them to implement open RDRs to support these researchers. Open RDRs increase visibility within HILs and reduce research data loss, and research works will be cited and used publicly. This paper identifies the potential for additional studies focussed on this area.
Evaluating the intention to use Industry 5.0 (I5.0) drones for cleaner production in Sustainable Food Supply Chains: an emerging economy context
Authors: Mahroof Kamran , Omar Amizan , Vann Yaroson Emilia , Tenebe Samaila Ado , Rana Nripendra P. , Sivarajah Uthayasankar , Weerakkody Vishanth 
Published: October 2023

Purpose
The purpose of this study is to evaluate food supply chain stakeholders’ intention to use Industry 5.0 (I5.0) drones for cleaner production in food supply chains.

Design/methodology/approach
The authors used a quantitative research design and collected data using an online survey administered to a sample of 264 food supply chain stakeholders in Nigeria. The partial least square structural equation model was conducted to assess the research’s hypothesised relationships.

Findings
The authors provide empirical evidence to support the contributions of I5.0 drones for cleaner production. The findings showed that food supply chain stakeholders are more concerned with the use of I5.0 drones in specific operations, such as reducing plant diseases, which invariably enhances cleaner production. However, there is less inclination to drone adoption if the aim was pollution reduction, predicting seasonal output and addressing workers’ health and safety challenges. The findings outline the need for awareness to promote the use of drones for addressing workers’ hazard challenges and knowledge transfer on the potentials of I5.0 in emerging economies.

Originality/value
To the best of the authors’ knowledge, this study is the first to address I5.0 drones’ adoption using a sustainability model. The authors contribute to existing literature by extending the sustainability model to identify the contributions of drone use in promoting cleaner production through addressing specific system operations. This study addresses the gap by augmenting a sustainability model, suggesting that technology adoption for sustainability is motivated by curbing challenges categorised as drivers and mediators.
Meta‐analysis of clinical risk factors for suicide among people presenting to emergency departments and general hospitals with suicidal thoughts and behaviours
Authors: Grover Cameron , Huber Jacqueline , Brewer Matthew , Basu Ashna , Large Matthew 
Published: October 2023

AbstractBackgroundSuicidal thoughts and behaviours (STB) are a common reason for presentation to emergency departments and general hospitals. A meta‐analysis of the strength of clinical risk factors for subsequent suicide might aid understanding of suicidal behaviour and help suicide prevention.MethodsWe conducted a meta‐analysis of cohort and controlled studies on clinical risk factors and later suicide among people presenting to emergency departments and general hospitals with STB. Data were extracted from papers meeting inclusion criteria, published in Medline, PsycINFO, and Embase between 1 January 1960 and 10 October 2022 using papers located with the search terms ((suicide*).m_titl AND (emergency* OR accident and emergency OR casualty OR general hospital OR toxicology service).mp) or were indexed in PubMed and had titles located with the search terms (suicide* OR self‐harm OR self‐harm OR self‐injury OR self‐injury OR self‐poisoning OR self‐poisoning OR overdose OR para‐suicide OR parasuicide [title/abstract]) AND (Emergency department OR emergency room OR Casualty OR general hospital OR toxicology OR accident and emergency [all fields]). Data about the association between clinical risk factors and suicide extracted from three or more studies were included in a random‐effects meta‐analysis of the odds of later death by suicide. The study was registered in PROSPERO and conducted according to MOOSE and PRISMA guidelines.ResultsSeventy‐five studies reported on 741,624 people, of which 19,649 died by suicide (2.65%). Male sex (odds ratio (OR) = 1.99) and age (OR = 2.01) were the most consistently reported risk factors. The strongest associations with subsequent death by suicide related to violent self‐harm methods at the hospital presentation, including: unspecified violent method (OR = 4.97), any violent method (OR = 4.57) and the specific violent methods of drowning (OR = 4.32), hanging (OR = 4.26), and use of firearms (OR = 10.08). Patients categorised as higher risk using suicide prediction scales or any other method that combined risk factors had moderately increased odds of suicide (OR = 2.58). Younger age, Black and Hispanic ethnicity, overdose, a diagnosis of adjustment disorder, and the absence of any psychiatric diagnosis were protective against suicide.ConclusionsMost risk factors for suicide among people who have presented with STB are not strongly associated with later suicide. The strongest risk factors relate to self‐harm methods. In the absence of clear indicators of future suicide, all people presenting with suicidality warrant a thorough assessment of their needs, and further research is needed before we can meaningfully categorise people with STB according to suicide risk.