bluuebunny/crossref_metadata_2025_split huggingface dataset:
Maternal autoimmune disease and risk of offspring autism spectrum disorder – a nationwide population-based cohort study
Authors: Chen Ching-Chu , Lin Ching-Heng , Lin Ming-Chih 
Published: November 2023

IntroductionAutism spectrum disorder (ASD) is a group of neurodevelopmental disorders which cause long term social and behavior impairment, and its prevalence is on the rise. Studies about the association between maternal autoimmune diseases and offspring ASD have controversial results. The aim of this study was to investigate whether maternal autoimmune diseases increase the risk of ASD in offspring from a population-based perspective.MethodsThe data sources were Taiwan’s National Health Insurance Research Database (NHIRD) and Taiwan’s Maternal and Child Health Database (MCHD), which were integrated and used to identify newborns whose mothers were diagnosed with autoimmune disease. Newborns were matched by maternal age, neonatal gender, and date of birth with controls whose mothers were without autoimmune disease using a ratio of 1:4 between 2004 and 2019. Data on diagnoses of autoimmune disease and autism spectrum disorders were retrieved from NHIRD. Patients who had at least 3 outpatient visits or at least 1 admission with a diagnosis of autoimmune disease and autism spectrum disorders were defined as incidence cases. The risks of ASD in offspring were compared between mothers with or without autoimmune disorders.ResultsWe identified 20,865 newborns whose mothers had been diagnosed with autoimmune disease before pregnancy and matched them at a ratio of 1:4 with a total of 83,460 newborn whose mothers were without autoimmune disease, by maternal age, neonatal gender, and date of birth. They were randomly selected as the control group. The cumulative incidence rates of autism spectrum disorders (ASD) were significantly higher among the offspring of mothers with autoimmune diseases. After adjusting for cofactors, the risk of ASD remained significantly higher in children whose mother had autoimmune diseases. Regarding to specific maternal autoimmune disease, Sjögren’s syndrome and rheumatoid arthritis were both associated with elevated risks of ASD in offspring.ConclusionMother with autoimmune disease might be associated with increasing the risk of autism spectrum disorder in offspring.
The impact of Chinese COVID-19 pandemic on the incidence of peripheral facial nerve paralysis after optimizing policies
Authors: Yu Erhui , Jin Fanyuan , Zhou Wenhui , Chen Junkang , Cai Huafeng , Hu Jinhua , Xuan Lihua 
Published: November 2023

ObjectiveTo evaluate the impact of the COVID-19 pandemic on the occurrence of Peripheral Facial Nerve Paralysis (PFNP) in Chinese patients, identify contributing factors, and explore the relationship between COVID-19 and PFNP.MethodsWe conducted a retrospective study covering the years 2020 to 2023, categorizing patients into three groups based on their visit dates: Group 1 (December 8, 2020 to February 28, 2021), Group 2 (December 8, 2021 to February 28, 2022), and Group 3 (December 8, 2022 to February 28, 2023). We collected and compared data on disease onset and patient characteristics among these groups.ResultsIn Group 3, following the widespread COVID-19 outbreak, there was a significant increase of 22.4 and 12.1% in PFNP cases compared to the same periods in the preceding 2 years (p &lt; 0.001). Group 3 patients were more likely to be aged between 30 and 60 years, experience onset within 7 days, present with Ramsay Hunt syndrome, and have a higher H-B score of VI compared to the previous 2 years (p &lt; 0.017). Logistic regression analysis revealed a strong association between the COVID-19 pandemic and the incidence of Ramsay Hunt syndrome in PFNP (OR = 3.30, 95% CI 1.81–6.03, p &lt; 0.001).ConclusionThe incidence of PFNP increased in China after the COVID-19 pandemic, particularly in patients with Ramsay Hunt syndrome, indicating that COVID-19 infection can trigger and worsen PFNP.
Variability analysis of muscle activation symmetry to identify indicators of individual motor strategy: a case series on elite Paralympic powerlifters
Authors: Rum Lorenzo , Romagnoli Ruggero , Lazich Aldo , Sciarra Tommaso , Balletti Nicoletta , Piacentini Maria Francesca , Boraschi Alessandro , Bergamini Elena 
Published: November 2023

IntroductionIn Paralympic powerlifting competitions, movement execution symmetry is a technical requirement influenced by individual athlete characteristics and motor strategies. Identifying the elements associated with individual motor strategies can offer valuable insight for improving sport performance. Therefore, this case series study aimed to explore muscle activation symmetry and its intra- and inter-individual variability to determine the muscles mostly related to individual motor strategies in elite Paralympic powerlifters.MethodsBilateral electromyographic activation of the anterior deltoid (AD), pectoralis major (PM), latissimus dorsi (LD), triceps (TRI) and external oblique (EO) muscles were analysed in five elite Paralympic powerlifters while performing four sets of one-repetition maximum of Paralympic bench press. Muscle activation symmetry indexes (SI) were obtained and transformed to consider individual-independent evaluation. The coefficient of variation (CV), variance ratio (VR), and mean deviation (MD) were computed to assess inter- and intra-individual variability in electromyographic waveforms and SI.ResultsBoth transformed and non-transformed SI indicated overall symmetric activation in DA, PM, TRI, and LD. Transformed SI revealed asymmetrical muscle activation of EO when grouping data (mean bilateral difference: 10%). Athletes exhibited low intra-individual SI variability in all analysed muscles (CV &lt; 10%) and low inter-individual variability in DA, PM, LD, and TRI (CV &lt; 10%; VR: 4%–11%; MD: 29%–43%). In contrast, higher inter-individual variability was observed in EO (CV: 23%; VR: 23%; MD: 72%–81%).ConclusionThe highest variability and asymmetry in abdominal muscle activation among athletes emphasize the importance of personalized training approaches for targeting these muscles due to their role in individualizing motor strategies.
Multimodal Semantic Knowledge Assessment –Standard and Preliminary Data in Semantic Variant Primary Progressive Aphasia and Alzheimer’s Disease in Comparison with Vascular Aphasia
Authors: Basaglia-Pappas Sandrine , Bourgey Romane , Boulangé Anne , Amiot Pauline , Champeaux Élise , Rendón de la Cruz Aurelia , Lefebvre Laurent , Simoes Loureiro Isabelle 
Published: November 2023

Les troubles lexico-sémantiques sont connus pour être l’une des manifestations majeures de l’aphasie, qu’elle soit d’origine vasculaire (comme l’aphasie sémantique -AS-) ou dégénérative (comme l’aphasie sémantique progressive primaire -APPvs- et la maladie d’Alzheimer -MA-). En pratique clinique, ces troubles sont principalement évalués par des tests verbaux, alors que, selon la littérature, le déficit doit être observé dans plusieurs modalités. Le but de cette étude était de créer une batterie française d’évaluation sémantique multimodale appelée EMCS (Évaluation Multimodale des Connaissances Sémantiques), qui étudie, en un temps plus court que les outils existants, l’efficacité de la mémoire sémantique à travers plusieurs tâches multimodales.	Quatre-vingt-sept participants témoins français ont été recrutés. Ils ont subi les 10 tâches de la batterie EMCS, à savoir les modalités verbales et non verbales. Pour explorer la sensibilité de la batterie, trois patients AS, deux APPvs et deux MA au stade débutant de la maladie ont réalisé l’EMCS.	Analyses et résultats : Les analyses statistiques ont permis d’établir des données normatives, avec des scores en percentiles, et ont mis en évidence, pour les témoins, un effet du niveau d’éducation pour la majorité des tests, un effet d’âge pour plusieurs tâches, mais pas d’effet de sexe. Pour chaque patient, les résultats se sont montrés discriminants par rapport au groupe témoin de référence pour plusieurs tâches, à savoir la dénomination d’images, les connaissances sémantiques sur les célébrités et l’épreuve gustative (p < 0,05). Discussion / Conclusion : La batterie EMCS peut contribuer à identifier, en un temps relativement court, des troubles sémantiques multimodaux chez des patients souffrant d’aphasie vasculaire et dégénérative. Ainsi, cet outil peut être une aide au diagnostic clinique et offre au clinicien la possibilité de déterminer, à un stade précoce, la nature de l’atteinte sémantique (accès ou centrale).
Personality and organizational strategies in episodic memory: The role of Openness to experience on recall and subjective organization in young and older adults.
Authors: Pinard Florent , Vanneste Sandrine , Bouazzaoui Badiâa , Fay Séverine , Isingrini Michel , Angel Lucie , Borella Erika , Taconnat Laurence 
Published: November 2023

L’objectif de cette étude était d’examiner, chez des adultes jeunes et âgés, la relation entre l’ouverture à l’expérience, les capacités de stratégie d’organisation subjective et les performances de mémoire. Cinquante jeunes adultes et 41 adultes plus âgés ont appris une liste de mots non reliés sémantiquement et ont dû les rappeler successivement 3 fois, afin que nous puissions calculer un indice d’organisation subjective ( Pair Frequency , PF). Le niveau d’ouverture a été mesuré à l’aide de la version française du NEO-PI-R (BFI-Fr) du questionnaire de personnalité Big-Five. Les adultes âgés ont rappelé et organisé moins de mots que les adultes jeunes. L’ouverture était positivement corrélée avec le rappel pour les deux groupes et avec le PF uniquement dans le groupe le plus âgé. Le PF et l’ouverture expliquent de manière significative le rappel chez les jeunes adultes, tandis que chez les adultes plus âgés, seule l’ouverture explique le rappel. L’ouverture n’a contribué au PF que chez les adultes plus âgés. Un score élevé d’ouverture pourrait être considéré comme un facteur de réserve, réduisant le déclin de la mémoire lié à l’âge en favorisant l’accumulation de connaissances et le développement de ressources tout au long de la vie.
Quels facteurs de risque associés ?
Authors: Askenazy Florence , Fernandez Arnaud , Gindt Morgane 
Published: November 2023

Le 14 juillet 2016, à Nice, un camion bélier a foncé dans la foule, tuant quatre-vingt-six personnes, dont quinze enfants, et faisant de nombreux blessés physiques et psychiques. Depuis, les recherches sur le psychotraumatisme pédiatrique se multiplient.
Une initiative qui fait ses preuves
Authors: Cailliez Apolline 
Published: November 2023

En 2021, à Angers, des professionnels se sont regroupés pour apporter aux jeunes un soin soutenu après leur prise en charge de crise en pédopsychiatrie. Ce dispositif permet d’organiser au mieux la suite du parcours et ainsi de prévenir la réhospitalisation.
Assessment of Psychiatric Comorbidities and Disability in Patients with a Complaint of Headache Attending Psychiatric Outpatient Department at Tertiary Care Center
Authors: Goyal Shri Gopal , Prakash Prem , Parihar Suresh , Verma K. K. 
Published: November 2023

Abstract

Background:
Headache is one of the most common complaints seen among the patients attending the psychiatric outpatient department. Psychiatric comorbidities worsen the headache and there is a vicious cycle of headache and psychiatric symptoms, aggravating each other. This further complicates headache management so it is better to explore psychiatric symptoms whenever we come across a headache patient.

Aims and Objectives:
The aim and objective of the study are to assess the psychiatric comorbidities and disability among the patients complaining of headaches.

Materials and Methods:
This was a cross-sectional study carried out at a tertiary care center. Patients attending the outpatient department with complaints of headaches were enrolled. Psychiatric comorbidities were assessed by using patient health questionnaire-9, generalized anxiety disorder-7 scale, depression, anxiety, and stress 21 scale along with allodynia symptom checklist-12. Disability in the past 3 months was assessed by Migraine Disability Assessment Scale (MIDAS) scale. A semi-structured Performa was used to record sociodemographic details and clinical variables.

Results:
Majority of the patients (69%) were of the age group 20–40 years. Females (75%) predominated in the study. The average severity of headaches reported by 63% of patients was moderate over Likert’s scale. Temple area (73%) was the main location. Throbbing (81%) was the main type of headache. One-third of the patients got compelled to wake at night due to headache attacks. The main premonitory symptoms were depression, irritability, and sensitivity to sound. Other associated symptoms during headache attacks were sensitivity to sound, anxiety, and irritability. Psychological stress was the main provoking factor. The majority of patients (75%) show mild disability in the past 3 months over the MIDAS scale. 25% of the patient-reported moderate depression over the patient health questionare-9 scale. The majority of the patients (85%) reported moderate-to-severe anxiety and nearly half of the patients reported severe stress.

Conclusion:
Patients with headaches have high chances of associated psychiatric comorbidities that make worse outcomes of each other so it is better to do detailed psychiatric workup and treat them efficiently keeping in view of psychiatric symptoms.
Logotherapy: Learnings from the Past and Relevance in the COVID-19 Pandemic
Authors: Malik Lipika , Khurana Hitesh 
Published: November 2023

Abstract
The experience of COVID-19 pandemic had been severely stressful for many of us. As the pandemic affected the whole world, many intellectuals described these experiences as stressful as during wartime. Human suffering and uncertainty about recovery or falling victim had been quite similar in both situations. Logotherapy developed by Dr. Viktor Frankl during World War II (WW-II) has the underpinning to search for meaning in such experiences that motivate the person to remain socially connected and look for better prospects in future. The therapy has the bases in the cognitive psychology, spirituality, and philosophy which are quite different from the modern-day practice of psychodynamic and cognitive therapies. The authors reviewed Viktor Frankl’s book “Man’s search of meaning” in the context of COVID-19 pandemic, and found marked similarities between the human suffering of the current situation and what Frankl has described in his book. In this narrative review, the authors have attempted to compare the situation during WW-II and current pandemic and have commented about the usefulness of practice of logotherapy in the current situation.
Prevalence of Depression among Patients of Type 2 Diabetes Mellitus without Overt Complications and Its Association with Glycemic Control in a Tertiary Care Center in India – A Cross-sectional Study
Authors: Anugraha Aswini , Kantipudi Suvarna Jyothi , Mahadevan Shriraam 
Published: November 2023

Abstract

Background:
The prevalence of type 2 diabetes is on the rise worldwide posing a serious threat to public health. In India, it has increased from 3.3% to 19% in urban and 2.4% to 15% in rural areas from 1972 to 2019. Depression is a major contributor to disability-adjusted life years (DALYs) and common comorbidity in diabetic patients. Studies show a bidirectional relationship between depression and diabetes. However, there is a dearth of evidence on the relationship between depressive symptoms and diabetes mellitus.

Aim:
This study aims to estimate the occurrence of depression in type 2 diabetic patients and to find the association between depression and glycemic control in a tertiary care center in Tamil Nadu, India.

Materials and Methods:
A cross-sectional study was done among type 2 diabetes mellitus patients of 18–65 years of age. Hemoglobin A1C levels were collected, and the Patient Health Questionnaire-9 (PHQ-9) was administered for screening depression. If PHQ ≥10, the Mini-international Neuropsychiatric Interview (MINI) was done to confirm the diagnosis of depression. The severity was assessed using the Hamilton Depression Rating Scale, and the Diabetes Self-Management Questionnaire was used to assess their self-management behaviors.

Results:
One hundred and fourteen patients (male = 36, female = 78) were screened for depression, and the diagnosis was confirmed with MINI. Twenty-six patients scored ≥10 scores, of which 8 (7%) met the criteria for moderate depression and 18 (15.8%) for mild depression. Eighty-eight (77.2%) had no depression. The characteristics significantly associated with depression were female gender, poor glycemic control, and systemic hypertension.

Conclusion:
There are clear evidence in the literature for an increased prevalence of depression in diabetic patients resulting in poorer prognosis. This study demonstrated the association of poor glycemic control with depression. Early diagnosis and multidisciplinary treatment approach addressing both disorders would help improve the global health burden by reducing mortality and DALYs.
Benthic foraminiferal patchiness – revisited
Authors: Schönfeld Joachim , Glock Nicolaas , Polovodova Asteman Irina , Roy Alexandra-Sophie , Warren Marié , Weissenbach Julia , Wukovits Julia 
Published: November 2023

Abstract. Many benthic organisms show aggregated distribution patterns due to the spatial heterogeneity of niches or food availability. In particular, high-abundance patches of benthic foraminifera have been reported that extend from centimetres to metres in diameter in salt marshes or shallow waters. The dimensions of spatial variations of shelf or deep-sea foraminiferal abundances have not yet been identified. Therefore, we studied the distribution of Globobulimina turgida dwelling in the 0–3 cm surface sediment at 118 m water depth in the Alsbäck Deep, Gullmar Fjord, Sweden. Standing stock data from 58 randomly replicated samples depicted a log-normal distribution of G. turgida with weak evidence for an aggregated distribution on a decimetre scale. A model simulation with different patch sizes, outlines, and impedances yielded no significant correlation with the observed variability of G. turgida standing stocks. Instead, a perfect match with a random log-normal distribution of population densities was obtained. The data–model comparison revealed that foraminiferal populations in the Gullmar Fjord were not moulded by any underlying spatial structure beyond 10 cm diameter. Log-normal population densities also characterise data from contiguous, gridded, or random sample replicates reported in the literature. Here, a centimetre-scale heterogeneity was found and interpreted to be a result of asexual reproduction events and restricted mobility of juveniles. Standing stocks of G. turgida from the Alsbäck Deep temporal data series from 1994 to 2021 showed two distinct cohorts of samples of either high or low densities. These cohorts are considered to represent two distinct ecological settings: hypoxic and well-ventilated conditions in the Gullmar Fjord. Environmental forcing is therefore considered to impact the population structure of benthic foraminifera rather than their reproduction dynamics.
Kinerja Kualitas Atraksi di Destinasi Wisata Kawasan Bandung Barat
Authors: Christy Caroline , Ervina Ersy , Sumarsih Umi 
Published: November 2023

Kawasan Bandung Barat telah lama terkenal sebagai destinasi wisata alam dan petualangan. Salah satu faktor penentu keberlangsungan destinasi wisata adalah Kualitas atraksi yang dapat memberikan kesan bagi wisatawan, sayangnya belum semua destinasi dapat bertahan lama. Tidak sedikit yang tutup karena tidak mampu memenuhi kepuasan wisatawan. Penelitian ini bertujuan untuk menganalisis tingkat kepuasan pengunjung terhadap kualitas atraksi di tempat wisata Bandung Barat. Wisatawan yang memenuhi persyaratan sebagai responden untuk mengisi dan memberikan informasi yang diperlukan dalam proses pengisian kuesioner adalah responden penelitian ini. Jumlah responden adalah 110 orang, dengan fokus pada empat (4) destinasi yang paling banyak dikunjungi wisatawan (Great Asia Africa, Floating Market, Sungai Cikahuripan, dan Farmhouse Lembang). Analisis Importance Performance Analysis (IPA) dan analisis Customer Satisfaction index (CSI) digunakan dalam penelitian ini untuk menganalisis tingkat kepuasan wisatawan. Hasil analisis IPA menunjukan bahwa atribut fasilitas destinasi yaitu atraksi menyajikan fasilitas yang nyaman masih belum memenuhi kepuasan wisatawan sehingga perlu ditingkatkan lagi fasilitasnya dan hasil penelitian menunjukkan bahwa pengunjung ke destinasi wisata Bandung Barat sebesar 85.00% merasa (sangat puas) berdasarkan CSI. Harapannya hasil penelitian ini bisa digunakan untuk meningkatkan kualitas kinerja atraksi yang telah dikembangkan.
DAMPAK KERUSAKAN LINGKUNGAN BIOTIK, ABIOTIK, DAN SOSIAL BUDAYA AKIBAT PERTAMBANGAN TIMAH ILEGAL DI KECAMATAN MENTOK
Authors: Putri Annisa Fitria Jasmine , Valensia Meisia Viona , Purnama Rafizah , Manik Jeanne Darc Noviayanti 
Published: November 2023

Provinsi Kepulauan Bangka Belitung memiliki sumber daya alam dan hasil bumi yang melimpah. Pertambangan timah di Bangka Belitung merupakan salah satu sektor utama dalam struktur ekonomi masyarakat. Dalam berkontribusi pada sektor ekonomi, pertambangan timah dapat dikatakan mampu memberikan kehidupan yang baik dan layak dalam rangka meningkatkan kesejahteraan masyarakat. Kegiatan penambangan timah baik yang dilakukan di darat maupun di laut tentunya berdampak besar bagi ekosistem lingkungan. Pengusaha tambang timah dan masyarakat seringkali mengabaikan konsekuensi yang timbul dari kegiatan penambangan timah. Kegiatan penambangan timah di Kepulauan Bangka Belitung, khususnya di Kecamatan Mentok, Kabupaten Bangka Barat, berdampak signifikan terhadap kerusakan ekosistem lingkungan. Tahap reklamasi tambang diperlukan untuk mengembalikan kondisi alam seperti semula. Penelitian ini dilakukan untuk mengetahui kepastian hukum terhadap dampak kerusakan lingkungan akibat penambangan timah ilegal yang terjadi. Dalam penelitian ini menggunakan metode penelitian yuridis empiris yang juga dapat disebut penelitian lapangan, yaitu mengkaji ketentuan hukum yang berlaku dan apa yang terjadi dalam kenyataan. Oleh karena itu, penelitian ini akan berfokus pada studi regulasi, implementasi, dan mengkaji masalah yang dihadapi. Apa dampak kerusakan lingkungan biotik, abiotik, dan sosial budaya akibat penambangan timah di Kecamatan Mentok, Kabupaten Bangka Barat, Provinsi Kepulauan Bangka Belitung? Apakah regulasi yang ada mampu memberikan kepastian hukum dalam meminimalisir terjadinya kerusakan lingkungan yang disebabkan oleh penambangan timah, khususnya penambangan timah ilegal? Oleh karena itu, kami ingin mempelajari lebih lanjut tentang masalah ini dan menyajikannya dalam sebuah penelitian