bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonsteroidal antiinflammatory drugs reduce anion secretion and increase apoptosis in equine colonic mucosa ex vivo
Authors: Vinijkumthorn Ruethaiwan , Bauck Anje G. , Vidyasagar Sadasivan , Freeman David E. 
Published: October 2023

Abstract

OBJECTIVE
Right dorsal colitis causes chronic colic associated with long-term treatment with nonsteroidal antiinflammatory drugs (NSAIDs). This study was designed to determine if NSAIDs could inhibit anion transporters that protect against intestinal mucosal injury in other species.

ANIMALS
20 healthy horses.

METHODS
The effects of indomethacin (INDO) and firocoxib (FIR), on short-circuit current (Isc) in mucosa from the right dorsal colon (RDC) and right ventral colon (RVC) were measured in Ussing chambers by standard electrophysiological techniques. Immunohistochemical methods were used to detect apoptosis (caspase-3) with these NSAIDs and phenylbutazone (PBZ) and to locate the NKCC1 transporter.

RESULTS
The Isc in RDC and RVC incubated with INDO or FIR was increased almost 3-fold (P < .0001) by prostaglandin E2 (PGE2) through a system inhibited by loop diuretics (P < .0001). Although these findings and anion replacement studies were consistent with anion secretion, the RDC also displayed an Isc response suggestive of a unique transporter apparently absent in RVC or NSAID-free solutions. In RDC, FIR, INDO, and PBZ induced apoptosis in the lower half of crypts. However, significant differences in apoptotic index were recorded in the RDC between NSAID-treated and control tissues (no NSAID).

CLINICAL RELEVANCE
The effects of NSAIDs on Isc were consistent with reduced anion secretion, which could represent the pharmacological equivalent of the transport failure responsible for Cystic Fibrosis (CF) in other species. Failure of anion secretion could interfere with buffering acid from intraluminal fermentation, which could suggest a treatment target for right dorsal colitis.
Identification of DNA methylation of CAPN10 gene changes in the patients with type 2 diabetes mellitus as a predictive biomarker instead of HbA1c, random blood sugar, lipid profile, kidney function test, and some risk factors
Authors: Smail Harem Othman , Mohamad Dlnya Asaad 
Published: October 2023

Abstract

Objective. Nowadays, type 2 diabetes mellitus (T2DM) is the most common chronic endocrine disorder, affecting an estimated 5–10% of adults worldwide and this disease rapidly increases in the Kurdistan region population. This research aims to identify DNA methylation change in the CPAN10 gene as a predictive biomarker in T2DM and the association between DNA methylation status with lipid profile and kidney function test.

Methods. The participants (113) were divided into three groups: diabetes group (47), prediabetes group (36), and control group (30). The study was carried out on patients who visited the private clinical sectors between August and December 2021 in the Koya city Kurdistan region of Iraq. To determine DNA methylation status, methylation-specific PCR (MPS) with paired primer for each methylated and unmethylated region was used. The Mann-Whitney U test and Spearman’s correlation were performed for statistical analysis of data and a value of p<0.05 was considered significant.

Results. The obtained results show that DNA hypermethylation was recorded in the promoter region in the samples of the diabetes and prediabetes groups compared to the healthy group (control). Various factors also affected the level of DNA methylation, such as HbA1c in prediabetes group and body mass index in the control group.

Conclusion. These results indicate that DNA methylation changes in the CAPN10 gene promoter region may be used as a potential predictive biomarker to diagnose T2DM; however, this study requires further data to support this evidence.
Promoting hotel employees’ work engagement and its service outcomes: The critical role of intrinsic motivation
Authors: Grobelna Aleksandra , Wyszkowska-Wróbel Ewa 
Published: October 2023

Abstract

Purpose
The purpose of this article is to investigate the relationship between intrinsic job-related motivators and hotel employees’ work engagement and to examine how it may correlate with important employees’ outcomes, such as the prescribed-role and extra-role customer service.

Design/methodology/approach
The literature review and empirical research based on a survey method were employed.

Findings
The findings revealed that there is a positive and significant correlation between intrinsic job-related motivators and hotel employees’ work engagement. It was also demonstrated that work engagement significantly and positively correlates with both the prescribed-role and extra-role customer service provided by employees.

Originality/value
This study adds to the growing body of research on employees’ work motivation, particularly focusing on the intrinsic dimension that it has still not received enough empirical attention in the literature of both hotel management and marketing.
Does deterioration in rule of law per se create or destroy value?
Authors: Byrka-Kita Katarzyna , Czerwiński Mateusz , Bajerska Aurelia 
Published: October 2023

Abstract
We investigate the link between the rule of law and equity returns in post-transitional economies over the period January 2010–December 2020 by using panel data regressions. By applying several rule-of-law proxies for national legal frameworks and justice system quality as proxies for the rule-of-law principle, the data sets from the capital markets of Poland, Latvia, Lithuania, and Estonia showed that country-level judicial system quality is an important driver of company market performance, and that post-transitional countries with lower rule-of-law measures exhibit higher returns on equity than those with better measures. Our results support the idea that since poor governance and country instability increase agency and transaction costs, in addition to decreasing growth prospects and profitable projects available to companies, the risk premium demanded by investors increases, leading to higher equity returns.
Optimisation of Model Predictive Torque Control Strategy with Standard and Multi-Objective Genetic Algorithms
Authors: Zerdali Emrah , Gurel Aycan 
Published: October 2023

Abstract
In this paper, the flux error-related weighting factor (WF) of the predictive torque control (PTC) strategy for induction motor (IM) control is optimised by a standard genetic algorithm (SGA) through speed errors only and multi-objective genetic algorithm (MOGA) through torque and flux errors. This paper compares the performances of both optimisation methods. Compared to MOGA, SGA offers a straightforward way to select WF and does not need a decision-making method to choose a final solution. But MOGA considers the given problem in a multi-objective way and directly optimises the control objectives of the PTC strate-gy. Comparisons are made over the flux and torque ripples, total harmonic distortion of stator phase current, and average switching frequency for different operating conditions. Simulation results show that both methods choose a close WF value. Consequently, SGA stands out in the optimisation of the PTC strategy with its simple structure.
Dementia literacy and familiarity with term dementia: An exploratory study from a psychiatry outpatient setting
Authors: Malik Yogender Kumar , Ray Adwitiya , Singh Shipra , Gupta Rajiv 
Published: October 2023

Objectives:
Dementia, often misperceived as an inherent facet of aging, is, in fact, a progressive neurodegenerative condition. It carries a significant stigma due to its associated psychological and behavioral manifestations, leading to neglect and abuse within households. Studies reveal an alarming 90% treatment gap for dementia in India, largely due to limited knowledge about symptom recognition and accessing services. Thus, enhancing dementia literacy becomes crucial for early diagnosis and proper management. This study aims to assess dementia literacy and familiarity with the term “dementia” in a North Indian tertiary health-care setting.

Materials and Methods:
This cross-sectional study used a case vignette method among patients and their attendants at psychiatry outpatient setting in a tertiary care hospital. A validated Hindi-translated case vignette depicting a dementia patient was employed. The study gathered sociodemographic data, the case vignette, and three related questions. Participants read the vignette and provided answers. The analysis included 200 responses collected in 1 month.

Results:
Respondents predominantly associated the case’s condition with memory issues, mental illness, and psychosocial factors. They suggested social support, a nurturing family environment, communal living, and consulting a doctor for the protagonist. Familiarity with “dementia” was at a mere 24%.

Conclusion:
Dementia literacy and awareness of “dementia” are notably low in our sample. Urgent efforts are required to enhance dementia awareness to facilitate timely prevention, early detection, and effective management.
The Altruistic Connection: Unraveling How Altruism Drives Eco-Friendly Consumer Behavior in Green Marketing (Literature Review)
Authors: Yulianti Farida , Zulfikar Rizka , Lamsah  
Published: October 2023

Purpose: This article explores research on eco-conscious marketing (2010-2022) via sources like Scopus, ScienceDirect, Emerald, and Taylor & Francis. Altruism, acting selflessly for others, significantly impacts eco-friendly choices.

Theoretical framework: This research examines altruism's role in eco-friendly marketing through behavioral theories. Limited analysis of psychological links and cultural norms exists. Further investigation is needed for sustainable consumer behavior and ethical exchange.

Methodology: In the effort to comprehend the complex connection between altruism and green marketing, a strong methodology has arisen through the combination of qualitative research techniques and a comprehensive examination of existing literature. This description presents the methodological process utilized to examine the impact of altruism on research related to green marketing from 2010 to 2022. This exploration involves the gathering of data, its analysis, and the development of meaningful insights, all drawn from reliable sources such as Scopus, Emerald, ScienceDirect, Taylor & Francis, and Google Scholar.

Findings: In the context of green marketing, altruism is pivotal for comprehending and shaping consumer behavior. Beyond economic factors, it embraces emotions, ethics, and communal welfare. Altruism-driven strategies hold promise for positive change, brand loyalty, and sustainability. Research spanning 2010-2020 uncovers gaps in understanding altruism's mechanisms, contexts, sustainability, trade-offs, extensions, and interactions, necessitating their exploration for effective green marketing and a sustainable world.

Research, Practical & Social implications: The research identifies gaps in comprehending altruism's psychological aspects, context influences, and sustainability. This enhances strategies for sustainable consumer behavior. Additionally, leveraging altruism supports green marketing's effectiveness, bridges the "value-action gap," and fosters brand loyalty, thereby harnessing its potential for positive change, a greener future, and enhanced brand allegiance.

Originality: Employing qualitative research methods and extensive literature review, this study explores the link between altruism and green marketing from 2010 to 2022. The synthesis of findings reveals altruism's role in shaping consumer behavior, with implications for marketing strategies, bridging value-action gap, and fostering brand loyalty. Research gaps underscore the need for investigating psychological mechanisms, contextual influences, and sustainability.
THE CONCEPT OF UTILITARIANISM IN THE SHORT STORY “THE ONES WHO WALK AWAY FROM OMELAS” IN “THE WIND'S TWELVE QUARTERS” BY URSULA KROEBER LE GUIN
Authors: Azizah Siti Nurrohmah , Hikmat Mahi M. 
Published: October 2023

This study examines the concept of utilitarianism presented in the short story "The Ones Who Walk Away from Omelas" in "The Wind's Twelve Quarter" by Ursula K. Le Guin. Through an ethical approach in sociology literature, this study aims to analyze the ethical implications of collective action in achieving general happiness in Omelas. Through analysis of the sociology of literature, this study reveals the social practices of utilitarianism presented in the story. In utilitarianism through ethical theory developed by philosophers Jeremy Bentham and John Stuart Mill, argues that a good action is an action that produces as much happiness as possible for as many people as possible. In the context of this short story, society has collectively chosen to maintain general happiness by ignoring the fate of the oppressed individual. This raises deep ethical questions about the justice and morality of emotional action. This study also analyzes the attitudes of individuals who choose to leave Omelas. This action shows disapproval of the principle of utilitarianism which sacrifices one individual for the sake of broad happiness. The attitude of individuals who dare to walk raises ethical overtones about our responsibilities to society and individuals. Through an analysis of ethical theory in a literary sociology approach, this study concludes that "The Ones Who Walk Away from Omelas" pushes to limit the ethical boundaries of utilitarianism and change moral compromises in achieving peace. The social and psychological implications of this story awaken our awareness of the moral dilemmas associated with emotional action and raise deep ethical questions about human values ​​and justice.
Keywords: Utilitarianism, Sociology of Literature, Ethics
Desain E-modul Mata Kuliah Seni Tembang Macapat bagi Mahasiswa MBKM Lintas Program Studi
Authors: Nur Hasan Latif , Marsudi Marsudi , Retno Utami Respati , Lani Anggapuspa Meirina , Alfiranda Zahroh Adinda 
Published: October 2023

Cross-study courses are one of the programs of the Independent Campus Free Learning Curriculum. One of the courses offered across study programs by the Javanese Language and Literature Education Study program is the Macapat Song Arts Course. As a beginner learner in a song course, students will of course experience several problems, namely:1) The tone in the song is different from the tone of modern music (diatonic) which is usually heard and sung. Songs use pentatonic, so adjustments need to be made. 2) There are two types of tunings that students must also master, namely pelog and slendro with a different tone too. 3) Men's and women's voices have different ranges so they require different treatment. 4) the types of cengkok/types of songs in Macapat vary greatly, making it more difficult to memorize. In effort to ensure that students outside the Javanese Language and Literature Education study program need special treatment so that it is easier for them to take courses. Researchers in this case will design an Electronic Module for the Song Arts Course so that it can help students outside the Java study program learn Macapat songs. This research using the R&D Level 1 model, namely researching, producing designs, but not testing and producing them. Validation carried out by Javanese language material experts with a score of 3.7 and validation by design experts received a score of 3.78.
Keywords: E Module, Macapat Song Art, MBKM Lintas Prodi
Characteristic of White Glutinous Sticky Rice “Kipang” added by Coconut Dregs
Authors: Sayuti Kesuma , Refdi C,W , Ramadani P 
Published: October 2023

This study aimed to determine the effect of coconut dregs addition on white glutinous sticky rice “Kipang” characteristics. The study used a CRD with six treatments and three replications. The treatments applied in this study is coconut dreg, consisting of A (0%), B (5%), C (10%), D (15%), E (20%), and F (25%). The data were analyzed using ANOVA and subsequently subjected to DNMRT at the 5% significance level. The study showed that adding coconut dreg affected moisture content, protein, fat, carbohydrates, crude fiber, total sugar, and organoleptic acceptance such as color, taste, and crispiness. However, it did not significantly affect the ash content and the organoleptic acceptance of the aroma. The best treatment was F product (25%) with moisture content (6.44%), ash content (0.93%), fat content (13.4%), protein content (3.17%), carbohydrates content (75.73%), crude fiber (4.47%), total sugar (42.88%) and organoleptic acceptance for color 4.43 (like), aroma at 4.23 (like), taste 4,33 (like) and fragility at 4.23 (like). The glycemic index of the product was (67.92%)
The Relationship between Perception and Anxiety in HIV Patients at the Victory Plus Foundation in Yogyakarta
Authors: Setyorini Andri , Sari Sekar 
Published: October 2023

Perception is the last process of observation which initiated by the sensory process, namely the process of receiving a stimulus by the senses, then there is attention, then it passed on to the brain, and only then the person realizes. HIV / AIDS is a dangerous chronic disease. It is undeniable that HIV / AIDS is not only a health problem, but also a problem and consequences on social, spiritual, and psychological aspects. Objective: To analyze the relationship between perceptions and anxiety in HIV patients at Yayasan Victory Plus Yogyakarta. The research design used a correlational study with a cross sectional approach. Population of patients in this study were 30 HIV patients who received assistance at the Yogyakarta Victory Plus Foundation. The sampling technique used in this study was total sampling, as well as statistical tests used by Kendall's Tau. The results showed a significant relationship between perceptions and anxiety in HIV patients at Yayasan Victory Plus Yogyakarta, with a p value of 0.000 (p <0.01) and Kendall's Tau correlation coefficient of -, 894 **. There is a significant relationship between perceptions and anxiety in HIV patients where the negative correlation results mean that the higher the perception, the more normal anxiety in HIV patients.Key words: HIV patients; Perception; Worry
The Description of Infectious Waste Management by Nurses Stationed at Inpatient Room of Arifin Achmad General Hospital of Riau Province
Authors: Arum Dhea Putri Primadana 
Published: October 2023

Hospital activities produce various kinds of hospital waste, one of which is infectious waste. Infectious waste management that is not good can cause health and environmental problems. This study aims to see an overview of infectious waste management by nurses in class III inpatient rooms (Dahlia, Edelweis, Kenanga, Krisan) Arifin Achmad Regional General Hospital, Riau Province. This study uses a simple descriptive design with the number of respondents 66 nurses using a total sampling technique. The data collection method in this study used a questionnaire. The analysis used is univariate analysis. The results of this study explained that as many as 48 nurses carried out infectious waste management well (72.7%). a total of 50 nurses have good knowledge of waste management (75.8%). The type of infectious waste in the treatment room is the majority of waste contaminated with patients in the isolation ward such as gauze, swab bandages, and other contaminated waste. a total of 50 nurses performed the waste sorting method well (75.8%) and 51 nurses performed the waste collection method well (77.3%). Overall, the nurses in the ward have performed the infectious waste management well. This research is expected so that nurses can further improve the quality of waste management in the inpatient room so that it will be even better in the future. Keywords: Infectious waste; Waste management;Nurses
SIDE EFFECTS OF HEMODIALYSIS IN CHRONIC KIDNEY DISEASE (CKD) PATIENTS WITH ALOE VERA GEL
Authors: Faizah Maulida Umi 
Published: October 2023

Patients with chronic kidney disease or Chronic Kidney Disease (CKD) really need action that can help replace the role of the kidneys in the body. One of the actions that can be taken is hemodialysis therapy, where this therapy is able to replace kidney function by filtering blood using a special machine at an unaffordable cost. However, hemodialysis also has side effects, one of which is skin problems such as xerosis, dry skin or xerosis, which is a skin disorder caused by loss of lipids and natural moisturizing factors in the stratum corneum. Problems that arise as a result of hemodialysis actions, of course, also require treatment such as providing moisturizers for xerotic skin. The method used in this research is a literature review study. Database searches via Pubmed, Science Direct, Elsevier, Jama, and Google Scholar. Based on searches and case study results from 5 articles, the effectiveness of aloe vera gel has been proven to overcome skin problems through research. It has been proven that aloe vera gel can moisturize the skin because aloe vera gel contains water with a water content of 99% and, besides that, it also contains glucomannans, amino acids, lipids, sterols and vitamins. Aloe vera gel is indeed effective for treating skin problems such as dry skin without having to spend a lot of money, so it can minimize cost overruns in patients undergoing hemodialysis therapy on a regular or even long-term basis. Keywords: Chronic Kidney Failure; Hemodialysis; Xerosis; Aloe Vera Gel
EFFECTIVENESS OF MINDFULNESS ON PSYCHONEUROIMUNOLOGI : SYSTEMATIC REVIEW
Authors: Abidin Zaenal , Fauzi Abdul , Iskandar Iskandar 
Published: October 2023

Permasalahan pada psikoneuroimunologi (PNI) dapat mengakibatkan pemburukan status kesehatan apabila tidak ditangani dengan baik. Mindfulness diketahui memberikan efek yang baik terhadap perbaikan pada permasalahan PNI. Tujuan penulisan sistematik review ini adalah untuk mengetahui efektivitas terapi mindfulness terhadap psikoneuroimunologi. Penelitian ini dilakukan dengan melakukan pencarian artikel-artikel pada database Scopus, ScienceDirect, Proquest, Pubmed, CINHL dan Springerlink yang telah di publikasi dengan batasan tahun 2013 hingga 2019. Adapun keyword yang digunakan adalah “Mindfulness” AND “Psychoneuroimmunology” OR “Psycho” OR “Neuro” OR “Immunology”. The Centre for Review and Dissemination and the Joanna Briggs Institute Guideline sebagai panduan dalam memilih dan menentukan kualitas studi yang dirangkum. Jurnal yang dipilih dalam penulisan sitematik review ini adalah jurnal yang menggunakan desain Randomized Controlled Trial atau Randomized Clinical Trial. Pelaporan systematic review ditulis dengan menggunakan panduan checklist dari PRISMA. Pemilihan jurnal berdasarkan kata kunci yang digunakan menghasilkan 928.420 berpotensi studi yang relevan. 282.078 duplikasi dihapus dan 646.201 judul dan abstrak yang ditemukan 24 jurnal yang di review menunjukkan bahwa mindfulness berpengaruh terhadap PNI antara lain Mindfulness-Based Cognitive Therapy (MBCT), Mindfulness-Based Cancer Recovery (MBCR), Mindfulness-based intervention (MBI), Mindfulness Meditation (MM) durasi intervensi antara 3 hari – 8 minggu. Mindfulness memberikan efek ketenangan dan kenyamanan sehingga mampu meningkatkan perbaikan melalui peningkatan imunologis dalam masalah kesehatan yang dimediasi seperti penyakit menular, kanker, autoimunitas, alergi, dan penyembuhan luka, fungsi kekebalan, relaksasi dan hipnoterapi dan meningkatkan suasana hati. Beberapa jenis mindfulness berpengaruh baik terhadap psikoneuroimunologi tetapi dalam penulisan ini belum dapat ditentukan jenis mindfulness yang paling efektif. Sehingga perlu dilakukan pemilahan jenis mindfulness ketika menerapkan pada pasien tertentu.