bluuebunny/crossref_metadata_2025_split huggingface dataset:
Single Atom Silver‐Phosphors in Titanosilicate Matrix for Enhanced LED Applications
Authors: Romolini Giacomo , Sun Li , Fron Eduard , Acapito Francesco d’ , Grandjean Didier , Roeffaers Maarten B.J. , Martìn Cristina , Hofkens Johan 
Published: November 2023

AbstractSmall metal oligomers have gained significant attention due to their exceptional optoelectronic properties and versatile applications, ranging from sensors to imaging and catalysis. However, the need for matrices (silica, zeolites, or metal‐organic frameworks) to prevent aggregation into larger metallic particles reduces their potential applicability in light‐emitting devices (LEDs) due to their poor electrical properties. To address this issue, a novel semiconductor stabilizer, titanosilicate, is proposed as an innovative solution for Ag‐based luminescent materials. These results show that titanosilicate, characterized by high thermochemical stability and well‐defined semiconducting properties, is an ideal scaffold for Ag‐luminescent species. Optical spectroscopic techniques reveal that Ag‐titanosilicates feature an orange fluorescence with a photoluminescence quantum yield reaching 20%. In contrast, a combination of X‐ray diffraction, TEM, and XEOL‐X‐ray absorption spectroscopic techniques show that, unlike zeolites, the luminescent species consist of single Ag atoms. The electroluminescent properties of the proposed Ag‐titanosilicate are further investigated within a conventional LED architecture by using the new material as an emissive layer. The developed proof‐of‐concept LED exhibits a significant improvement of the ZEOLEDs, where a smaller low turn‐on voltage of 2 V (enabling energy‐efficient operation) and high color rendering index of 80 introduces exciting prospects for developing advanced Ag‐LED phosphors.
Temperature Correction of Printed Na+, K+, and pH Sensors with PEDOT:PSS‐Based Thermistors toward Wearable Sweat Sensing
Authors: Shiwaku Rei , Matsui Hiroyuki , Nagamine Kuniaki , Tokito Shizuo 
Published: November 2023

AbstractTemperature correction for sensors is a critical aspect of ensuring accurate measurements in wearable devices, because skin and sweat temperatures vary between 20 and 40 °C depending on individual and time. Here, this study reports on the temperature dependence and correction techniques of printed Na+, K+, and pH sensors toward wearable applications. The ion sensor array is fabricated using a cost‐effective printing method. To enable temperature correction, a printed thermistor of crosslinked poly(3,4‐ethylenedioxythiophene):poly(styrenesulfonate) (PEDOT:PSS) is monolithically integrated with the ion sensor array on a flexible plastic substrate. Temperature dependence of the potential response of the printed ion sensors exhibits a linear behavior with a slope of 1–2 mV °C−1 in the physiological skin temperature range of 20–40 °C. Applying temperature correction to the ion sensors, the maximum relative errors are reduced from 60% to 7.8% for the Na+ sensors and from 76% to 14.6% for the K+ sensors, while the maximum absolute error is reduced from 0.88 to 0.19 for the pH sensors, indicating the critical importance of temperature correction as a technology for wearable printed ion sensors.
Copper Coordination‐Based Nanomedicine for Tumor Theranostics
Authors: Han Yuanfeng , Xie Nuli , Zhou Wenhu 
Published: November 2023

AbstractCopper (Cu) is an essential micronutrient for a variety of basic biological processes, including cell metabolism, proliferation, and angiogenesis. Recently, the concept of cuproptosis has been found to be related to the direct binding of Cu to the lipoylated components of the tricarboxylic acid cycle. This further demonstrates the important role of Cu and promotes Cu‐involved biomedical research. Currently, Cu‐related nanomedicines is mainly based on Cu coordination chemistry, and targeting Cu become a research hotspot for cancer therapy. On one hand, chelating excess Cu in vivo to inhibit angiogenesis, on the other hand, supplementing Cu and Cu‐coordinated complexes to produce oxidative stress and proteasome inhibition. In this review, the principles of Cu‐coordination chemistry and the biochemical functions of Cu ions are described, and a comprehensive review of Cu‐coordinated nanomedicine, including Cu chelation and Cu supplementation, delivery of Cu‐coordinated nanodrugs, and Cu‐coordinated nanocarriers is provided. Finally, the limitations are analyzed to point out the directions for improvement in future research. It is believed that the development of Cu‐coordinated nanomedicine will enter the fast track and show great promise in cancer theranostics.
Blue Light Potentiates Antibiotics in Bacteria via Parallel Pathways of Hydroxyl Radical Production and Enhanced Antibiotic Uptake
Authors: Leanse Leon G. , Anjos Carolina dos , Kaler Kylie Ryan , Hui Jie , Boyd Jeffrey M. , Hooper David C. , Anderson R. Rox , Dai Tianhong 
Published: November 2023

AbstractIn the age of antimicrobial resistance, the urgency by which novel therapeutic approaches need to be introduced into the clinical pipeline has reached critical levels. Antimicrobial blue light (aBL), as an alternative approach, has demonstrated promise as a stand‐alone therapeutic method, albeit with a limited window of antimicrobial activity. Work by others indicates that treatment with antibiotics increases the production of reactive oxygen species (ROS) which may, in part, contribute to the bactericidal effects of antibiotics. These findings suggest that there may be potential for synergistic interactions with aBL, that similarly generates ROS. Therefore, in this study, the mechanism of aBL is investigated, and the potential for aBL to synergistically promote antibiotic activity is similarly evaluated. Furthermore, the translatability of using aBL and chloramphenicol in combination within a mouse model of Acinetobacter baumanii burn infection is assessed. It is concluded that porphyrins and hydroxyl radicals driven by “free iron” are paramount to the effectiveness of aBL; and aBL is effective at promoting multiple antibiotics in different multidrug‐resistant bacteria. Moreover, rROS up‐regulation, and promoted antibiotic uptake are observed during aBL+antibiotic exposure. Lastly, aBL combined with chloramphenicol appears to be both effective and safe for the treatment of A. baumannii burn infection. In conclusion, aBL may be a useful adjunct therapy to antibiotics to potentiate their action.
Near‐Infrared‐Responsive Rare Earth Nanoparticles for Optical Imaging and Wireless Phototherapy
Authors: Du Pengye , Wei Yi , Liang Yuan , An Ran , Liu Shuyu , Lei Pengpeng , Zhang Hongjie 
Published: November 2023

AbstractNear‐infrared (NIR) light is well‐suited for the optical imaging and wireless phototherapy of malignant diseases because of its deep tissue penetration, low autofluorescence, weak tissue scattering, and non‐invasiveness. Rare earth nanoparticles (RENPs) are promising NIR‐responsive materials, owing to their excellent physical and chemical properties. The 4f electron subshell of lanthanides, the main group of rare earth elements, has rich energy‐level structures. This facilitates broad‐spectrum light‐to‐light conversion and the conversion of light to other forms of energy, such as thermal and chemical energies. In addition, the abundant loadable and modifiable sites on the surface offer favorable conditions for the functional expansion of RENPs. In this review, the authors systematically discuss the main processes and mechanisms underlying the response of RENPs to NIR light and summarize recent advances in their applications in optical imaging, photothermal therapy, photodynamic therapy, photoimmunotherapy, optogenetics, and light‐responsive drug release. Finally, the challenges and opportunities for the application of RENPs in optical imaging and wireless phototherapy under NIR activation are considered.
Rhodium‐Catalyzed Regioselective C7Ar‐Functionalization of Tryptophan with Quinones and its Late Stage Peptide Exemplification
Authors: Tank Disha Harsukhbhai , Kharat Narendra Dinkar , Bajaj Kiran , Panda Siva S. , Sakhuja Rajeev 
Published: November 2023

AbstractPivaloyl‐directed Rh(III)‐catalyzed regioselective C7Ar‐H functionalization of protected tryptophans were accomplished with 1,4‐benzoquinones, furnishing a series of quinone‐appended tryptophan‐based unnatural amino acids in high yields. Further, the late stage functionalization on tryptophan‐containing dipeptides was achieved with 1,4‐benzoquinones in moderate reactivity.
Al2O3‐coated BiVO4 Photoanodes for Photoelectrocatalytic Regioselective C−H Activation of Aromatic Amines
Authors: Wang Jinghao , Zuo Lulu , Guo Zhiyu , Yang Caoyu , Jiang Yuheng , Huang Xuewei , Wu Lizhu , Tang Zhiyong 
Published: November 2023

AbstractPhotoelectrochemistry is becoming an innovative approach to organic synthesis. Generally, the current photoelectrocatalytic organic transformations suffer from limited reaction type, low conversion efficiency and poor stability. Herein, we develop efficient and stable photoelectrode materials using metal oxide protective layer, with a focus on achieving regioselective activation of amine compounds. Notably, our photoelectrochemistry process is implemented under mild reaction conditions and does not involve any directing groups, transition metals or oxidants. The results demonstrate that beyond photocatalysis and electrocatalysis, photoelectrocatalysis exhibits high efficiency, remarkable repeatability and good functional group tolerance, highlighting its great potential for applications.
Poly(PEI‐catechol‐tetraethylenepentamine) was prepared by “one‐pot method” for removing Reactive Red 195
Authors: Liang Ze , Lu Lin , Gao Tingting , Liu Qinze , Yang Zhizhou , Zhou Ruoyao , Peng Guofeng , Yao Jinshui , Zhang Changbin 
Published: November 2023

AbstractWastewater containing dyes is frequently discharged by industrial processes and needs separation and recycling. To solve this problem, it is important to research and develop environmentally friendly, efficient adsorbent materials for pollutant separation and recovery. In this study, a poly(PEI‐catechol‐tetraethylenepentamine) (PPCT) adsorbent was synthesized using a simple catecholamine reaction. This adsorbent exhibited high adsorption capacity and excellent removal efficiency for Reactive Red 195 (RR‐195) in wastewater. The material was characterized using SEM, FT‐IR, TGA, EA, and XPS. Its performance was optimized by varying the type of polyethyleneimine and the amount added during the preparation process. The effects of temperature, pH, contact time, and salt concentration on the adsorption were systematically investigated. Additionally, the experimental data showed consistency with both the Langmuir and pseudo‐second‐order kinetic models, simultaneously. The maximum adsorption capacity can reach 1754 mg g−1 at 303 K, with a retention rate of 86.6% after two cycles. The removal rate exceeds 98% at a concentration of 400 mg g−1 or lower. Additionally, the protonated amine group in PPCT carries a positive charge under acidic conditions, enabling selective adsorption of the anionic dye RR‐195. Consequently, PPCT exhibits an excellent adsorption effect on RR‐195 and holds promising applications in pollutant removal.
Efficient synthesis of phosphorus containing melamine salt for enhancing flame retardancy of poly(lactic acid)/polyamide 11 blends
Authors: Jiang Peng , Chang Liang , Pan Fangya , Jia Hongyu , Chen Zhilin , Liang Shanqing 
Published: November 2023

AbstractA tetrakis (melamine)‐1‐hydroxyethylidene‐1,1‐diphosphonic acid salt (EA‐MEL) was synthesized by a straightforward acid–base neutralization reaction between 1‐hydroxyethylidene‐1,1‐diphosphonic acid (EA) and melamine (MEL). This compound, which contains phosphorus and nitrogen elements, exhibits a 40% carbon residue at a temperature of 800°C. When combined with diethyl aluminium hypophosphite (OP1230) as a flame‐retardant composite in polylactic acid (PLA)/polyamide 11 blends through melt blending, a synergistic effect between the two flame retardants is observed. Consequently, the limiting oxygen index value significantly increases to 34.3, showcasing a remarkable 64.6% improvement. Additionally, the material achieves a V‐0 rating according to UL‐94 standards, and the peak heat release rate drops to 269 kW∙m−2 with the addition of just 5 wt% EA–MEL. These results demonstrate that EA‐MEL and OP1230 contribute to the generation of phosphoric acid derivatives and the formation of a crosslinked (PN)n or (PON)n network. This network enables the formation of a complete, compact, and expanded char residue, effectively isolating heat and oxygen.
Evaluating Antibiofilm, Cytotoxic and Apoptotic Activities ofScutellaria brevibracteatasubsp.brevibracteataEssential Oil
Authors: Kart Naime Nur Bozbeyoğlu , Günal Batıkan , Mutlu Doğukan , Doğan Nazime Mercan , Arslan Şevki , Semiz Gürkan 
Published: November 2023

AbstractEssential oils have many important biological properties, including antibacterial and antibiofilm activities. These unique properties make, essential oils good alternatives to synthetic chemical drugs, which have many side effects. In this study, we aimed to determine the chemical composition and biological activity of the essential oil obtained fromScutellaria brevibracteatasubsp.brevibracteata. Specifically, its antibiofilm activity againstPseudomonas aeruginosaPAO1 andStaphylococcus aureusATCC 29213 biofilms using XTT assay. Cytotoxic and apoptotic properties of the essential oil were investigated in human lung cancer cells (A540 and H1299) using MTT assay, Annexin V‐FITC and propidium iodide staining and q‐PCR. Thirty‐two different compounds were identified from the essential oil, of which elemol (20.42 %), γ‐eudesmol (20.12 %) and β‐eudesmol (14.85 %) were the main components. The essential oil was more effective againstP. aeruginosaPAO1 biofilm (79 %) thanS. aureusATCC 29213 biofilm (27 %). The specific activity of the essential oil againstP. aeruginosabiofilm may be related to its high terpene contents. In addition, the essential oil showed high cytotoxic activity towards A549 (IC509.09 μg/ml) and H1299 (IC5055.04 μg/ml) cell lines, inducing apoptosis in these cancer cells. These results demonstrate the antibiofilm and anticancer activities ofS. brevibracteatasubsp.brevibracteataessential oil.
Comparative study of different biological processing methods on nutritional composition and bioactivity of whole‐grain wheat
Authors: Shi Zongqing , Zhang Duqin , Tian Xiaohong , Tan Bin 
Published: November 2023

AbstractBackground and ObjectivesBiological processing is considered one of the most effective technologies used to eliminate adverse traits and improve the quality of cereal. To compare the effects of different biological processing methods on the nutritional value and bioactivity of whole‐grain wheat (WGW), solid‐state fermentation (SSF), germination (GT), solid‐state fermentation (SSF), germination (GT), and phytase treatment (PT) were performed.FindingsAfter biological processing, protein, insoluble dietary fiber, and bound flavonoid contents significantly increased, while phytate, bound phenolic, and free flavonoid contents obviously decreased. The molar ratio of phytate content to mineral content, including PA/Ca, PA/Fe, and PA/Zn, significantly reduced by 13.8%–42.0%, 8.4%–73.4%, and 17.9%–45.0%, respectively, suggesting the improvement of mineral bioavailability. The greatest reduction of phytate content was found in WGW after PT. In comparison to SSF and PT, GT significantly improved phenolic content and 2,2‐azinobis (3‐ethylbenzothiazoline‐6‐sulfonic acid) and 1, 1‐diphenyl‐2‐picrylhydrazyl free radical scavenging abilities of free phenolic extract in WGW. As compared to GT and PT, the ORAC of the free phenolic extract in WGW obviously improved after SSF with strains of Lactobacillus plantarum, Saccharomyces cerevisiae, and Monascus sp.ConclusionsOverall, SSF, GT, and PT showed high efficiency in phytate degradation, and GT and SSF, in particular, improved the nutritional value and bioactivity of WGW.Significance and NoveltyThis study provides data supporting the use of different biological processing methods based on different objectives when preparing WGW products.
Use of molecular simulation for evaluating adsorption equilibrium of inhalation anaesthetic agents on metal–organic frameworks
Authors: Haeri‐Nejad Masoud , Eic Mladen 
Published: November 2023

AbstractMetal–organic frameworks (MOFs) were studied as alternatives to zeolites and activated carbon for adsorptive removal of wasted inhalation anaesthetic agents (IAA). Monte Carlo simulation was used to predict equilibrium adsorption isotherms of IAA on selected MOFs. Rather than generic forcefields (FFs), the all‐atom FF parameters published by Arcario were used for IAA modelling. Continuous fractional component Monte Carlo (CFCMC) proved crucial for speedy simulation of large molecules. We found that allocating 70% probability to the CFlambdaSwap move gave optimum fits between simulation and experiment. The simulations provided us with an insight into the adsorption mechanisms of IAA in these structures. Heats of adsorption, Brauner‐Emmet‐Teller (BET) surface area, and total pore volume were deduced to be the crucial parameters for low, medium, and high range of relative pressures in the isotherm. Therefore, the chromium atoms in MIL‐101‐Cr are better adsorbers of IAA than MIL‐100‐Al at lower pressures despite the similarities in terms of the type of linkers and topology. Our simulation results corroborated the earlier published studies on the self‐association behaviour of sevoflurane molecules based on the experimental isotherms reported for MOF‐177‐Zn. Finally, the high polarity of IAA is thought to explain good low‐pressure simulation/experiment data agreement for the MOFs possessing coordinatively unsaturated sites (CUS) despite using generic DREIDING FF for the framework atoms. Our in‐house parsing code helped realize that the grand‐canonical Monte‐Carlo simulation speed is not the same for all pressure points but decreases for higher pressure points. This can be explained by increased density of the adsorbates making successful trial moves less probable.
Evaluation and economic value of Hedera colchica in urban land management
Authors: Mirhosseini Mahsa Sadat , Saeb Keivan , Kiadaliri Masoud , Rahnavard Aptin 
Published: November 2023

AbstractCarbon sequestration is the process of capturing, securing and storing carbon dioxide from the atmosphere. In this study, the carbon sequestration capacity of Hedera colchica was investigated in soil of a semiarid region in Iran. Samples were taken from plants cultivated in the semiarid area of the polluted metropolis of Tehran and the amount of sequestered carbon in the aboveground and underground parts of the plant was measured. The conversion coefficient of carbon sequestration of plant organs (stem, leaf, and root) was determined separately by the combustion method. Carbon tax policy was used to evaluate the carbon sequestration function, as the shadow price of carbon. The results showed a significant difference in the amount of carbon sequestration in different organs of the plant. Stems and roots with 29.3 and 4.3 t ha−1, respectively, showed the highest and lowest amount of carbon deposition. The results of the economic value showed that the carbon shadow price was $40567.6 ha−1 on average. In general, the results of this study showed that the organs of H. colchica can have a beneficial effect in the process of carbon sequestration.
Adaptive power permutation modulation: A novel transmission technique for increased spectral efficiency over fading channels
Authors: Özyurt Serdar 
Published: November 2023

SummaryIn this study, we propose a novel transmission technique for multiple‐input multiple‐output (MIMO) systems as a partial response to ever‐growing demand for the increased spectral efficiency. The introduced scheme, called adaptive power permutation modulation (APPM), relies on the distinct power allocations on the conventionally modulated symbols to convey a certain number of additional information bits. Unlike the traditional power allocation strategies which generally aim to combat the channel fading and entail some form of channel state information (CSI) at the transmit side, APPM utilizes different power levels to convey additional information and does not necessitate any kind of CSI at the transmitter. The proposed approach is applied to two well‐known MIMO configurations, Alamouti space‐time block coding and zero‐forcing beamforming, by embracing a general frequency‐selective fading scenario under digital phase modulation. Both the modulation order and the power allocation levels on the modulated symbols are adaptively determined based on a set of additional information bits. It is shown that in addition to the conventionally modulated symbols, an extra sequence of
bits can be conveyed without any significant additional complexity where
equals the number of subcarriers. Also, it is demonstrated that considerable transmit power savings can be attained when compared with the standard schemes under a certain target spectral efficiency.
Multifunctional coatings hinging on the catechol/amine interplay
Authors: Alfieri Maria Laura , Panzella Lucia , Napolitano Alessandra 
Published: November 2023

AbstractDesign and implementation of functional coatings is a topic of active research in a variety of health‐related applications, most of which require wet adhesion. The powerful wet adhesion of mussel byssus proteins rich in DOPA and lysine residues provided a clue to realize that the combination of a catechol and an amine component has a specific role in the interfacial adhesion. From this natural model, polydopamine (PDA)‐based coatings have been developed that result from the oxidative polymerization of dopamine combining the catechol and amine functionalities in the same molecule. Covalent interactions resulting from Michael‐type addition or Schiff‐base formation of the polymeric products from dopamine oxidation as well as non‐covalent π‐stacking and cation‐π interactions exemplify the diverse mode of catechol/amine interplay that have been identified as responsible of the adhesion and cohesion properties of PDA. In the last decade coatings inspired to the same chemistry but using different starting materials have been explored particularly catechols of natural origin and different amine components, while mechanistic studies with model compounds have allowed to rationalize the structural requirements for adhesion and to expand the potential of these functional coatings.
A novel three‐step DNA extraction method for mixed bloodstains
Authors: Huang Jian , Huang Yushong 
Published: November 2023

AbstractMixed DNA samples from at least two contributors can be present at a crime scene, which could be the most crucial piece of genetic evidence. The mixed stains in sexual assault cases are typically separated using differential lysis procedures (a two‐step method). Blood mixed stains, however, are usually difficult to separate. In this work, we propose that a mixed stain comprises three layers, that is, (1) the upper layer which is primarily made up of cells from one contributor; (2) the middle layer which is a similar mixture from two contributors; and (3) the lower layer which primarily comprises cells from the other contributor. Based on this concept, a novel three‐step DNA extraction method was proposed to solve the challenge involving bloodstains from two contributors. In the experiment, we extracted three layers DNA from mixed bloodstains using three steps. As a result, single‐source DNA and approximate single‐source DNA were detected from steps 1 and 3, respectively. This study demonstrates that the DNA from some mixed blood stains could be effectively separated following an appropriate extraction strategy, providing valuable insights, and serving as a reference for future examination of blood mixtures.