bluuebunny/crossref_metadata_2025_split huggingface dataset:
Species distribution modelling and population genetic analysis ofYushania anceps; an endemic temperate woody bamboo of the Uttarakhand Himalayas
Authors: Meena Rajendra K. , Negi Nitika , Bhandari Maneesh S. , Shankhwar Rajeev , Yadav Abhishek , Kant Rama , Pandey Shailesh , Sharma Rajesh 
Published: November 2023

AbstractYushania ancepsis a temperate woody bamboo taxon of high socio-economic importance occurring in the sub-alpine zone of the western Himalayas. This study was carried out to delineate the potential distribution ofY. ancepsin the western Himalayas through species distribution modelling (SDM), and genetic characterization using sequence-tagged microsatellite (STMS) markers. The present study revealed an endemic distribution of this species in the Uttarakhand Himalayas, with an estimated area of 211.59 km2. The maximum probability of occurrence was recorded in the moderately dense forests between the altitudinal ranges of 2500 and 2700 m. The model output was well supported with high values of different statistical measures, such as the AUC (0.911) and Kappa coefficient (K= 0.513). Environmental variables related to precipitation, temperature and topography were identified as the most contributory in current SDM. In addition, diversity measures, namely allelic richness (Ar), expected heterozygosity (He), and fixation index (FST), were calculated in five sampled populations with eight STMS markers, which indicated high genetic diversity (Ar = 4.24; He = 0.689) and little differentiation (FST= 0.062). The diversity maps displayed that the populations located in the Kumaon region captured relatively more genetic diversity than the Garhwal region. Further, genetic clustering and STRUCTURE analysis revealed a substantial level of genetic admixing across the analysed populations, and as a result, no sub-structuring was detected. Due to the rare and endemic distribution ofY. anceps, it requires immediate conservation measures, and the knowledge base generated here will be of paramount importance to forest managers, researchers and policymakers.
Reappraising the Narrative of Dato Mogul and Singora's Early History
Authors: Khoo Benjamin J.Q. , Dalrymple Graham H. 
Published: November 2023

AbstractThis article surveys and analyses the available materials on Dato Mogul, the putative first ruler of Singora (present-day Songkhla) in the early seventeenth century. It argues that the narrative in Thailand surrounding Dato Mogul and his emergence is sketchy at best. In reviewing the literature and drawing on new and extant primary sources, we argue that Dato Mogul was likely a Malay governor authorised by Ligor. This reappraisal presents a more accurate biographical narrative and provides greater insight on polity formation in Lower Siam in the period under review.
A Deformed Wedge‐Top Basin Inverted During the Collapse of the Variscan Belt: The Permo‐Carboniferous Lorraine Basin (NE France)
Authors: Hemelsdaël R. , Averbuch O. , Beccaletto L. , Izart A. , Marc S. , Capar L. , Michels R. 
Published: November 2023

AbstractA new structural model is presented for the Permo‐Carboniferous Lorraine Basin (NE France), a major intramountain basin that developed during the latest stages of the Variscan orogeny (ca. 315–270 Ma). Digitalized well logs and reprocessed seismic data were used to decipher the kinematic evolution of this basin located along the Rhenohercynian orogenic suture zone. The basin was initiated during the late collision stage (Early to Middle Pennsylvanian) in a wedge‐top position upon the Saxothuringian retro‐wedge. The syn‐orogenic sequence is delimited to the north by the major SE‐verging Metz Thrust, which is part of the backthrust system that propagated during Middle Pennsylvanian (Late Westphalian). Seismic data provide evidence of negative tectonic inversion, allowing the formation of syn‐rift depocenters (Late Pennsylvanian‐Early Permian) above the former anticlines. Erosion of these anticlines results in a major unconformity marking the onset of post‐orogenic collapse. The late Early Permian shortening (Saalian phase) is suggested to reactivate former thrusts and normal faults, thus generating late uplift of the basin. The post‐orogenic phase is complex and diachronous at basin scale, and both compression and extension can be recorded in the same area over a short period (<10 Myr). The Late Carboniferous negative tectonic inversion along the Rhenohercynian suture zone is proposed to result from the lithospheric delamination of the Variscan orogenic roots. The associated upwelling of asthenospheric material is recorded by intense magmatic activity, and can be, in turn, considered as the main trigger for the subsequent thermal subsidence of the Mesozoic Paris Basin.
A Sea State Dependent Gas Transfer Velocity for CO2 Unifying Theory, Model, and Field Data
Authors: Zhou Xiaohui , Reichl Brandon G. , Romero Leonel , Deike Luc 
Published: November 2023

AbstractWave breaking induced bubbles contribute a significant part of air‐sea gas fluxes. Recent modeling of the sea state dependent CO2 flux found that bubbles contribute up to ∼40% of the total CO2 air‐sea fluxes (Reichl & Deike, 2020, https://doi.org/10.1029/2020gl087267). In this study, we implement the sea state dependent bubble gas transfer formulation of Deike and Melville (2018, https://doi.org/10.1029/2018gl078758) into a spectral wave model (WAVEWATCH III) incorporating the spectral modeling of the wave breaking distribution from Romero (2019, https://doi.org/10.1029/2019gl083408). We evaluate the accuracy of the sea state dependent gas transfer parameterization against available measurements of CO2 gas transfer velocity from 9 data sets (11 research cruises, see Yang et al. (2022, https://doi.org/10.3389/fmars.2022.826421)). The sea state dependent parameterization for CO2 gas transfer velocity is consistent with observations, while the traditional wind‐only parameterization used in most global models slightly underestimates the observations of gas transfer velocity. We produce a climatology of the sea state dependent gas transfer velocity using reanalysis wind and wave data spanning 1980–2017. The climatology shows that the enhanced gas transfer velocity occurs frequently in regions with developed sea states (with strong wave breaking and high significant wave height). The present study provides a general sea state dependent parameterization for gas transfer, which can be implemented in global coupled models.
Understanding the Contributions of Paleo‐Informed Natural Variability and Climate Changes to Hydroclimate Extremes in the San Joaquin Valley of California
Authors: Gupta Rohini S. , Steinschneider Scott , Reed Patrick M. 
Published: November 2023

AbstractTo aid California's water sector to better understand and manage future climate extremes, we present a method for creating a regionally consistent ensemble of plausible daily future climate and streamflow scenarios that represent natural climate variability captured in a network of tree‐ring chronologies, and then embed anthropogenic climate change trends within those scenarios. We use 600 years of paleo‐reconstructed weather regimes to force a stochastic weather generator, which we develop for five subbasins in the San Joaquin Valley of California. To assess the compound effects of climate change, we create temperature series that reflect projected scenarios of warming and precipitation series that have been scaled to reflect thermodynamically driven shifts in the distribution of daily precipitation. We then use these weather scenarios to force hydrologic models for each of the five subbasins. The paleo‐forced streamflow scenarios highlight periods in the region's past that produce flood and drought extremes that surpass those in the modern record and exhibit large non‐stationarity through the reconstruction. Variance decomposition is employed to characterize the contribution of natural variability and climate change to variability in decision‐relevant metrics related to floods and drought. Our results show that a large portion of variability in individual subbasin and spatially compounding extreme events can be attributed to natural variability, but that anthropogenic climate changes become more influential at longer planning horizons. The joint importance of climate change and natural variability in shaping extreme floods and droughts is critical to resilient water systems planning and management in the San Joaquin.
Ecosystem CO2 Exchange and Its Economic Implications in Northern Permafrost Regions in the 21st Century
Authors: Mu Cuicui , Mo Xiaoxiao , Qiao Yuan , Chen Yating , Wei Yuguo , Mu Mei , Song Jinyue , Li Zhilong , Zhang Wenxin , Peng Xiaoqing , Zhang Guofei , Zhuang Qianlai , Aurela Mika 
Published: November 2023

AbstractClimate warming increases carbon assimilation by plant growth and also accelerates permafrost CO2 emissions; however, the overall ecosystem CO2 balance in permafrost regions and its economic impacts remain largely unknown. Here we synthesize in situ measurements of net ecosystem CO2 exchange to assess current and future carbon budgets across the northern permafrost regions using the random forest model and calculate their economic implications under the Shared Socio‐economic Pathways (SSPs) based on the PAGE‐ICE model. We estimate a contemporary CO2 emission of 1,539 Tg C during the nongrowing season and CO2 uptake of 2,330 Tg C during the growing season, respectively. Air temperature and precipitation exert the most control over the net ecosystem exchange in the nongrowing season, while leaf area index plays a more important role in the growing season. This region will probably shift to a carbon source after 2,057 under SSP5‐8.5, with a net emission of 17 Pg C during 2057–2100. The net economic benefits of CO2 budget will be $4.5, $5.0, and $2.9 trillion under SSP1‐2.6, SSP2‐4.5, and SSP5‐8.5, respectively. Our results imply that a high‐emission pathway will greatly reduce the economic benefit of carbon assimilation in northern permafrost regions.
Ultrahigh‐Temperature Anatexis of Metapelites Generates Near‐Anhydrous Garnet Granitoids
Authors: Wang Bin , Wei Chunjing , Tian Wei , Tang Ming 
Published: November 2023

AbstractIt remains unresolved whether extensive granitoids can originate from ultrahigh‐temperature crustal anatexis beyond the stability of fusible hydrous minerals and, if any, how they are generated and characterized. Here we investigate near‐anhydrous garnet granitoids in the Jining Complex, North China, using bulk‐rock and mineral analyses combined with phase equilibria modeling. The Jining garnet granitoids are parautochthonously emplaced within granulite terranes and diagnostically contain perthite, abundant garnet but minor biotite. The rocks exhibit high maficity (FeOT + MgO) of 4–12 wt.%, minimal H2O contents below ∼0.16 wt.% and limited aluminum saturation indexes within 1.1–1.7. Their magmas are scarcely fractionated and have ultrahigh temperatures of 1000–1100°C as revealed by K‐feldspar rich in anorthite (10–13 mol.%) and Ti (175−276 ppm), and garnet rims depleted in heavy rare‐earth elements that crystallize from melts. Besides, these magmas have deficient H2O contents (<∼0.19 wt.%) and high densities and viscosities. The garnet granitoids are generated by metapelite anatexis at ultrahigh‐temperature conditions likely around ∼1100°C, with selective entrainment of 5–40 vol.% residua, and underwent some melt loss during magma crystallization. The melting temperatures are far beyond biotite stability and close to the crustal dry solidus. Garnet‐involved congruent melting reactions are required to produce the maficity‐rich and H2O‐deficient melts with high capability for entraining residua. The ultrahigh‐temperature garnet granitoids differ from ordinary low‐ and high‐temperature garnetiferous granites in both petrologic features and petrogenesis, and represent a new subcategory of S‐type granitoids. They can indicate mantle‐actuated extreme crustal thermal perturbations.
Exploring the Connection of XVI‐Century Major Historical Earthquakes in the Eastern Betic Cordillera, Spain: Insights From Viscoelastic Relaxation of the Lithosphere
Authors: Yazdi Pouye , García‐Mayordomo Julián , Álvarez‐Gómez José Antonio , Gaspar‐Escribano Jorge Miguel , Masana Eulália 
Published: November 2023

AbstractUnderstanding the crustal fault interaction and connection between earthquakes in areas with slow tectonic deformation, such as Betic Cordillera (South Spain), is challenging. When seismic rates are low and large destructive earthquakes happen less frequently, it is necessary to resort to historical or paleoseismic records. This study investigates the postseismic viscoelastic relaxation mechanism as a potential explanation for the occurrence of three historical earthquakes (IEMSVIII‐IX) in the Eastern Betic Shear Zone during the XVI‐century, all of which occurred within a span of 13 years: 1518 Vera Mw6.2, 1522 Alhama de Almeria Mw6.5, and 1531 Baza Mw6.2 associated with the Palomares, Carboneras, and Baza faults, respectively. The results strongly suggest a sequential stress‐triggering connection between the three events. The northern NS‐oriented section of the Baza fault is found to have experienced a larger positive ΔCFS and, indeed, more prone to rupture in 1531. The study also examines whether the cumulative ΔCFS had influenced the occurrence of further significant earthquakes (≥Mw6.0) in the region. A triggering connection between the cascade and the 1658 Almeria Mw6.2 earthquake is suggested, whereas no indications of similar linkage to the 1674 Lorca Mw6.0 or the 1804 Dalias Mw6.4 events are found. The stress triggering impact of the cascade over nearby active faults is noteworthy. It is expected that this analysis could have future applications for studying other important historical events, and improving seismic hazard analysis in complex fault settings of the Betic Cordillera.
An umbrella review of candidate predictors of response, remission, recovery, and relapse across mental disorders
Authors: Solmi Marco , Cortese Samuele , Vita Giovanni , De Prisco Michele , Radua Joaquim , Dragioti Elena , Köhler-Forsberg Ole , Madsen Nanna M. , Rohde Christopher , Eudave Luis , Aymerich Claudia , Pedruzo Borja , Rodriguez Victoria , Rosson Stella , Sabé Michel , Hojlund Mikkel , Catalan Ana , de Luca Beatrice , Fornaro Michele , Ostuzzi Giovanni , Barbui Corrado , Salazar-de-Pablo Gonzalo , Fusar-Poli Paolo , Correll Christoph U. 
Published: November 2023

AbstractWe aimed to identify diagnosis-specific/transdiagnostic/transoutcome multivariable candidate predictors (MCPs) of key outcomes in mental disorders. We conducted an umbrella review (protocol link), searching MEDLINE/Embase (19/07/2022), including systematic reviews of studies reporting on MCPs of response, remission, recovery, or relapse, in DSM/ICD-defined mental disorders. From published predictors, we filtered MCPs, validating MCP criteria. AMSTAR2/PROBAST measured quality/risk of bias of systematic reviews/individual studies. We included 117 systematic reviews, 403 studies, 299,888 individuals with mental disorders, testing 796 prediction models. Only 4.3%/1.2% of the systematic reviews/individual studies were at low risk of bias. The most frequently targeted outcome was remission (36.9%), the least frequent was recovery (2.5%). Studies mainly focused on depressive (39.4%), substance-use (17.9%), and schizophrenia-spectrum (11.9%) disorders. We identified numerous MCPs within disorders for response, remission and relapse, but none for recovery. Transdiagnostic MCPs of remission included lower disease-specific symptoms (disorders = 5), female sex/higher education (disorders = 3), and quality of life/functioning (disorders = 2). Transdiagnostic MCPs of relapse included higher disease-specific symptoms (disorders = 5), higher depressive symptoms (disorders = 3), and younger age/higher anxiety symptoms/global illness severity/ number of previous episodes/negative life events (disorders = 2). Finally, positive trans-outcome MCPs for depression included less negative life events/depressive symptoms (response, remission, less relapse), female sex (response, remission) and better functioning (response, less relapse); for schizophrenia, less positive symptoms/higher depressive symptoms (remission, less relapse); for substance use disorder, marital status/higher education (remission, less relapse). Male sex, younger age, more clinical symptoms and comorbid mental/physical symptoms/disorders were poor prognostic factors, while positive factors included social contacts and employment, absent negative life events, higher education, early access/intervention, lower disease-specific and comorbid mental and physical symptoms/conditions, across mental disorders. Current data limitations include high risk of bias of studies and extraction of single predictors from multivariable models. Identified MCPs can inform future development, validation or refinement of prediction models of key outcomes in mental disorders.
Postpartum and non-postpartum depression: a population-based matched case-control study comparing polygenic risk scores for severe mental disorders
Authors: Munk-Olsen Trine , Di Florio Arianna , Madsen Kathrine B. , Albiñana Clara , Mægbæk Merete L. , Bergink Veerle , Frøkjær Vibe G. , Agerbo Esben , Vilhjálmsson Bjarni J. , Werge Thomas , Nordentoft Merete , Hougaard David M. , Børglum Anders D. , Mors Ole , Mortensen Preben Bo , Liu Xiaoqin 
Published: November 2023

AbstractIt remains inconclusive whether postpartum depression (PPD) and depression with onset outside the postpartum period (MDD) are genetically distinct disorders. We aimed to investigate whether polygenic risk scores (PGSs) for major mental disorders differ between PPD cases and MDD cases in a nested case-control study of 50,057 women born from 1981 to 1997 in the iPSYCH2015 sample in Demark. We identified 333 women with first-onset postpartum depression (PPD group), who were matched with 993 women with first-onset depression diagnosed outside of postpartum (MDD group), and 999 female population controls. Data on genetics and depressive disorders were retrieved from neonatal biobanks and the Psychiatric Central Research Register. PGSs were calculated from both individual-level genetic data and meta-analysis summary statistics from the Psychiatric Genomics Consortium. Conditional logistic regression was used to calculate the odds ratio (OR), accounting for the selection-related reproductive behavior. After adjustment for covariates, higher PGSs for severe mental disorders were associated with increased ORs of both PPD and MDD. Compared with MDD cases, MDD PGS and attention-deficit/hyperactivity disorder PGS were marginally but not statistically higher for PPD cases, with the OR of PPD versus MDD being 1.12 (95% CI: 0 .97–1.29) and 1.11 (0.97–1.27) per-standard deviation increase, respectively. The ORs of PPD versus MDD did not statistically differ by PGSs of bipolar disorder, schizophrenia, or autism spectrum disorder. Our findings suggest that relying on PGS data, there was no clear evidence of distinct genetic make-up of women with depression occurring during or outside postpartum, after taking the selection-related reproductive behavior into account.
Pathological roles of bone marrow adipocyte-derived monocyte chemotactic protein-1 in type 2 diabetic mice
Authors: Wan Shan , Xie Jinwei , Liang Yan , Yu Xijie 
Published: November 2023

AbstractType 2 diabetes mellitus (T2DM) has become a prevalent public health concern, with beta-cell dysfunction involved in its pathogenesis. Bone marrow adipose tissue (BMAT) increases in both the quantity and area in individuals with T2DM along with heightened monocyte chemotactic protein-1 (MCP-1) secretion. This study aims to investigate the influence and underlying mechanisms of MCP-1 originating from bone marrow adipocytes (BMAs) on systemic glucose homeostasis in T2DM. Initially, a substantial decrease in the proliferation and glucose-stimulated insulin secretion (GSIS) of islet cells was observed. Moreover, a comparative analysis between the control (Ctrl) group and db/db mice revealed significant alterations in the gene expression profiles of whole bone marrow cells, with a noteworthy upregulation of Mcp-1. And the primary enriched pathways included chemokine signaling pathway and AGE-RAGE signaling pathway in diabetic complications. In addition, the level of MCP-1 was distinctly elevated in BMA-derived conditional media (CM), leading to a substantial inhibition of proliferation, GSIS and the protein level of phosphorylated Akt (p-Akt) in Min6 cells. After blocking MCP-1 pathway, we observed a restoration of p-Akt and the proliferation of islet cells, resulting in a marked improvement in disordered glucose homeostasis. In summary, there is an accumulation of BMAs in T2DM, which secrete excessive MCP-1, exacerbating the abnormal accumulation of BMAs in the bone marrow cavity through paracrine signaling. The upregulated MCP-1, in turn, worsens glucose metabolism disorder by inhibiting the proliferation and insulin secretion of islet cells through an endocrine pathway. Inhibiting MCP-1 signaling can partially restore the proliferation and insulin secretion of islet cells, ultimately ameliorating glucose metabolism disorder. It’s worth noting that to delve deeper into the impact of MCP-1 derived from BMAs on islet cells and its potential mechanisms, it is imperative to develop genetically engineered mice with conditional Mcp-1 knockout from BMAs.
Achieving net-zero in the dry eye disease care pathway
Authors: Latham Samuel G. , Williams Richard L. , Grover Liam M. , Rauz Saaeha 
Published: November 2023

AbstractClimate change is a threat to human health and wellbeing across the world. In recent years, there has been a surge in awareness of this crisis, leading to many countries and organisations setting “net-zero” targets. This entails minimising carbon emissions and neutralising remaining emissions by removing carbon from the atmosphere. At the 2022 United Nations Climate Change Conference (COP27), commitments to transition away from fossil fuels and augment climate targets were underwhelming. It is therefore imperative for public and private sector organisations to demonstrate successful implementation of net-zero and set a precedent for the global political consensus. As a top 10 world employer, the United Kingdom National Health Service (NHS) has pledged to reach net-zero by 2045. The NHS has already taken positive steps forward, but its scale and complexity as a health system means stakeholders in each of its services must highlight the specifications for further progress. Dry eye disease is a chronic illness with an estimated global prevalence of 29.5% and an environmentally damaging care pathway. Moreover, environmental damage is a known aggravator of dry eye disease. Worldwide management of this illness generates copious amounts of non-recyclable waste, utilises inefficient supply chains and involves recurrent follow-up appointments and prescriptions. By mapping the dry eye disease care pathway to environmental impact, in this review we will highlight seven key areas in which reduced emissions and pollution could be targeted. Examining these approaches for improved environmental sustainability is critical in driving the transformation needed to preserve our health and wellbeing.