bluuebunny/crossref_metadata_2025_split huggingface dataset:
Experimental Justification of Reprofiling of the Drug Maxar® for the Treatment of Viral Infections
Authors: Zaporozhets T. S. , Krylova N. V. , Fedoreyev S. A. , Iunikhina O. V. , Pott A. B. , Tarbeeva D. V. , Mishchenko N. P. , Shchelkanov M. Yu. 
Published: October 2023

Relevance. The development of highly effective broad-spectrum antiviral agents is one of the priorities in medicine, virology, and pharmacology. The strategy of repurposing (repositioning) registered drugs is of special interest along with significant progress in this area due to the use of the latest technologies for target identification, discovery and optimization of the lead compound, biological testing. The advantages of repositioning are, among other things, in reducing the time and cost of some of the necessary stages of research.The aim of the work is to study the antiviral activity of the polyphenol complex (PPC) from Maackia amurensis, the active substance of the drug Maksar®, as well as to expand the field of medical application of the drug.Material and methods. The antiviral activity of PPC against herpes simplex virus type I (HSV-1) and enterovirus B (ECHO-1) grown on Vero cell culture was assessed by inhibition of the cytopathogenic effect (CPE) of the virus using the MTT assay.Results. PFC from Maackia amurensis wood effectively prevents the attachment of HSV-1 and ECHO-1 to Vero cells and exhibits high activity, exerting a virucidal effect, as well as inhibiting the early stage of viral particle replication.Conclusion. The data obtained expand the spectrum of pharmacological activity of Maxar® and determine the need for further studies of this drug in vivo to establish its antiviral properties in animal experiments. The final conclusion related to efficacy and safety can be drawn from the results of controlled randomized clinical trials with significant clinical results.
Impactos del Diseño de un Sistema de Gestión Ambiental en la Mitigación de los Índices de Contaminación en las Empresas del Sector Textil en Bogotá: Caso Puente Aranda
Authors: Moreno Cristancho Jesús Oswaldo 
Published: October 2023

El presente artículo se enfoca en la revisión del impacto que genera un sistema de gestión ambiental, a través de la implementación del objetivo que consiste en diseñar un sistema de gestión ambiental para la empresa en la mitigación de los índices de contaminación de las empresas del sector textil en Bogotá: caso Puente Aranda, desarrollado y estimados a partir de la aplicación de un instrumento que permitió validar la información de manera cuantitativa y cualitativa, donde se demuestra que el personal no tiene la conciencia cuidar y racionalizar los recursos ambientales, ni practican la cultura de los principios del PVA, a partir de los resultados analizados del proceso de indagación, de información primaria obtenida del estudio de contaminación del sector textil por localidades de Bogotá.
Pengaruh Penggunaan Edible Coating Berbahan Dasar Pati Pisang Goroho (Musaacuminafe, Sp) Terhadap Kualitas Buah Jambu Kristal (Psidium Guajava L) Selama Penyimpanan
Authors: Husain Sahrul Husain , Liputo Siti Aisa , Maspeke Purnama Ningsih 
Published: October 2023

Jambu biji (Psidium guajava L) merupakan buah yang tergolong dalam buah klimaterik, dengan demikian termasuk buah yang cepat mengalami kerusakan karena daya simpannya setelah panen pada suhu ruang yang tidak lama. Oleh karena itu untuk memperpanjang umur simpan adalah dengan penyimpanan dengan metode penggunaan edible coating berbahan dasar pati pisang goroho. Penelitian ini bertujuan untuk mengetahui pengaruh penggunaan edible edible coating terhadap kualitas jambu kristal selama penyimpanan. Metode yang digunakan adalah Rancangan Acak Lengkap (RAL). Penelitian dilaksanakan dalam 3 kali ulangan dan pengamatan dilakukan selama 12 hari setiap 6 hari sekali. Parameter yang diamati adalah vitamin C, susut bobot, laju respirasi, kadar air, dan organoleptik. Hasil analisis sidik ragam (0,05) menunjukkan bahwa pada perlakuan 3 % dan 5 % pati pada pelapisan edible coating memberikan perlakuan terbaik karena dapat menekan vitamin C, susut bobot, kadar air, laju respirasi dan organoleptik pada warna dan tekstur.Kata Kunci : Edible Coating, Pati Pisang Goroho, Jambu Kristal.
Prediksi Umur Simpan Dan Pengaruh Metode Pengemasan Terhadap Aktifitas Mikrobiologi Bubur Jagung Instan Terfortifikasi Ekstrak Daun Kersen (Muntingia Calabura L.)
Authors: Panigoro Mohamad Ikbal , Une Suryani , Ahmad Lisna 
Published: October 2023

Bubur jagung instan adalah produk pangan kering yang perlu di prediksi umur simpan serta potensi kerusakan akibat mikroorganisme, pengemasan memiliki pengaruh yang sangat besar dalam upaya melindungi hasil pengolahan atau produk industri dari bahaya pencemaran, gangguan fisik serta untuk mendapatkan bentuk yang memudahkan dalam penyimpanan, pengangkutan dan distribusi,serta sebagai promosi dan media informasi. Tujuan penelitian ini untuk mengetahui pengaruh jenis kemasan dan mikrobiologi terhadap umur simpan bubur jagung instan terfortifikasi ekstrak daun kersen. Penelitian ini menggunakan Rancangan Acak Lengkap (RAL) dengan satu faktor yaitu, jenis kemasan, Dengan 4 perlakuan dan di ulang sebanyak 3 kali. Parameter yang di uji yaitu Total Plate Count (TPC) dan prediksi umur simpan. Hasil penelitian umur simpan dengan kemasan pada kondisi RH 80% adalah 28, 60, 160, 329 hari. Hasil jumlah bakteri pada minggu ke 4 kemasan polipropilene mengalami peningkatan yaitu sebesar 201 x 106 pada kondisi non vakum dan 188,5 x 106 pada kondisi vakum dan jumlah mikroba kemasan laminatin aluminium foil pada minggu ke 4 dengan 282 x 106 pada kondisi non vakum serta 160,9 x 106 pada kondisi vakum. jumlah jamur dengan kemasan polipropilene pada minggu ke 4 mengalami peningkatan dengan 43,3 x 106 kondisi non vakum 37,9 x 106 pada kondisi vakum dan jumlah jamur dengan penggunaaan kemasan laminatin aluminium foil mengalami peningkatan pada minggu ke 4 dengan 47,5 x 106 kondisi non vakum dan 38,7 x 106 pada kondisi vakum.
Groundwater Diversity across New Zealand: From micro to macro-scale
Authors: Weaver Louise , Webber Judith , Abraham Phil , Bolton Annette , Sitthirit Panan , Close Murray 
Published: October 2023

Groundwater is home to a diverse range of organisms, both small and large, which form a complex ecosystem that helps to purify the water and keep it flowing smoothly. However, much of the processes that occur in this ecosystem are still a mystery and there are many important services that we have yet to fully understand.
Our goal is to create a groundwater health index that can be used to monitor the health of groundwater, similar to the macroinvertebrate community index used for surface water systems. We are investigating both the macroinvertebrates and microbial diversity in our research. To gather data, we are collecting groundwater environmental (e)DNA samples and biofilm samples using in-situ biofilm bags from various sites in New Zealand across multiple seasons. We then analyze the water chemistry and sequence data for bacteria, archaea, eukaryotes, and fungi to determine the status of the groundwater source.
Our findings show that there is a complex diversity present in both the groundwater itself (e.g., Fig. 1) and the attached microbial biofilm. We have also discovered variations between the attached and groundwater across all sites studied, with significant differences in the Shannon richness indicator in Canterbury. Additionally, we have observed differences in microbial populations depending on the lithology and water chemistry present.
Our research aims to identify key species, both micro and macro, that can potentially act as a tool for predicting the health of groundwater. Furthermore, understanding the biological processes occurring in our groundwater may lead to the discovery of beneficial organisms capable of remediation.
Pertanggungjawaban Pelaku Penyelundupan Migran Lintas Negara Ditinjau Dari Hukum Internasional
Authors: Lilipaly Neladi Frisilia , Tuhulele Popi , Daties Dyah Ridhul Airin 
Published: October 2023

Introduction: As a country with many small islands bordering other countries, Indonesia has considerable potential for migrant smuggling practices. The smuggling of illegal immigrants is a type of global crime.Purposes of the Research: aims to identify and analyze international law governing the smuggling of transnational migrants as well as to identify and analyze the accountability of perpetrators who smuggle transnational migrants.Methods of the Research: This legal research uses normative juridical research, case approach, statutory approach, and conceptual approach, primary and secondary legal materials, legal material procedures using primary legal materials which are then associated with secondary legal materials and processing and analysis of legal materials using qualitative descriptive analysis.Results of the Research: The results showed that the international legal arrangements that regulate migrant smuggling are the Palermo Convention (UN Convention / UNTOC) of 2000 concerning Transnational Crime (People Smuggling), the Migrant Workers Convention (International Labor Organization / ILO) of 1990, the Protocol for the Eradication of Smuggling involving People Smuggling 2000, and the perpetrators' accountability using the National Law or Indonesian Law, namely Law No. 6 of 2011 concerning Immigration.
Pengaruh Gaya Hidup, Citra Merek, dan Kualitas Produk terhadap Minat Beli Smartphone Iphone
Authors: Hidayah Munirotul Aina Bin Nur , Soebiantoro Ugy , Zawawi Zawawi 
Published: October 2023

Competition in the industrial world that is increasingly developing makes companies vying to optimally increase their resources. As well as social changes in Indonesian society towards perusahaan berjuang untuk meningkatkan kualitas sumber daya mereka sementara dunia teknologi dan informasi maju dengan sangat cepat. Bisnis dapat menggunakan segmentasi pasar sebagai salah satu teknik pemasarannya. Dengan penelitian ini, it analyzes related to iPhone smartphone products, which are well-known brands throughout the world so that they are familiar to consumers' minds, but the market share of these brands has decreased. This research was conducted to examine evaluated the external and internal models with Smart PLS 4.0 software to determine the impact of lifestyle, brand image, and product quality on iPhone purchase intentions through the use of Partial Least Square (PLS) Structural Equation Modeling (SEM). The method used to collect data is known as proportional stratified random sampling. Respondents were 90 samples of economics and business faculties who know iPhone products. These results indicate that lifestyle, brand image, and product quality can influence the intention to buy an iPhone smartphone
Keywords: Lifestyle, BrandImage, QualityProduct, PurchaseIntention
LITERASI AKUNTANSI BADAN USAHA MILIK DESA PADA BUMDES SILATRI INDAH WONOSOBO
Authors: Widaryanti Widaryanti - , Luhgiatno Luhgiatno - , Harminingtyas Rudika - 
Published: October 2023

AbstractBUMDES Silatri is one of the villages where BUMDes was established. BUMDes Silatri Indah as a partner does not prepare financial reports properly and is not in accordance with applicable accounting standards. Accounts are kept whenever a transaction occurs, regardless of accounting principle, and are limited to recording cash received and paid. This is because BUMDes treasurers do not have accounting education, and BUMDes managers have never received training on financial reporting, thus adding to the complexity of the problems faced by partners. The purpose of this event is to provide knowledge and understanding to prepare financial reports, therefore, through organizing seminars and training. The method of implementing PKM activities is educative. The educational approach discussed is providing knowledge and understanding of BUMDes Silatri Indah management which is reflected in seminars and organizing accounting training activities related to the preparation of BUMDes Silatri Indah financial reports. The results of community service activities are accounting understanding managers. In seminars and training events, BUMDes managers can record every transaction in financial reports in accordance with accounting rules. Keywords: BUMDES, Accounting Process, Financial Reports
PENERAPAN GOOGLE WORKSPACE FOR EDUCATION MELALUI PEMBELAJARAN BERBASIS PROYEK BAGI GURU MTs. M3R REMBANG
Authors: Mahmudi A. Aviv , Widodo Agustina , Migunani Migunani , Gunawan Bryan Adi , Maldani Melia 
Published: October 2023

Teknologi dan informasi berkembang pesat di dunia pendidikan, terutama di sekolah mulai sekolah dasar sampai perguruan tinggi MTs Mu’allimin Mu’allimat Rembang (M3R) merupakan salah satu madrasah di kota Rembang dan menjadi salah satu madrasah tsanawiyah tertua di antara madrasah lain dibawah naungan Kementrian Agama. MTs. M3R sebagai institusi pun dituntut untuk memberikan inovasi terbaru untuk membentuk proses pembelajaran yang sangat efektif, akan tetapi tidak semua guru/tenaga pendidik di belum paham betul mengenai inovasi terbaru yang harus dipakai untuk melakukan pembelajaran selama pandemi. Permasalahan yang dialami oleh mitra adalah model pembelajaran daring belum dapat dilakukan secara optimal karena kurangnya kemampuan guru-guru dalam mebuat konten/materi pembelajaran. Metode yang digunakan pada program PkM memberikan pelatihan dan praktek serta pendampingan pemanfaatan teknologi informasi dan komunikasi dalam kegiatan pembelajaran di sekolah menggunakan goggle workspace. Luaran dalam program {PkM ini adalah Guru menguasai dan mampu membuat serta menggunakan media pembelajaran goggle workspace dan mengimplementasikannya untuk media pembelajaran.
MENUMBUHKAN KECERDASAN LITERASI ANAK SEJAK DINI MELALUI KEGIATAN MENDONGENG PADA SISWA RA NUR INSANI JEMUR WONOSARI SURABAYA
Authors: Unsha Afina Faradila , Qibtiyah Anjeli Mariyatul , Nisabaha Athifah Zukhruf , Nurfadillah Atik Azzahra , Susilo Candra Bhakti , Miranda Marsha , Indriyani Jiphie Gilia , Atikurrahman Moh 
Published: October 2023

Mendongeng adalah suatu tradisi lisan yang dimiliki oleh bangsa Indonesia yang sudah ada sejak waktu yang lama yang bertujuan untuk membagikan pengalaman dan pengetahuan kepada orang lain, baik untuk remaja maupun anak-anak. Sastra anak merupakan kesusastraan yang menceritakan tentang pengetahuan keseharian anak dengan tujuan agar anak-anak dapat mempelajari contoh berkehidupan yang baik. Sastra anak dapat disampaikan kepada anak melalui tulisan dan lisan. Hal tersebut memudahkan kegiatan penyampaian dongeng kepada anak-anak.oleh sebab itu kami melaksanakan kegiatan pengabdian kepada masyarakat dengan mendongeng untuk anak di RA Nur Insani guna melestarikan kegiatan mendongeng.
ANALISIS FAKTOR-FAKTOR YANG MEMPENGARUHI KINERJA GURU
Authors: Hikmah Nurul , Tahwin Muhammad , Ilhami Susanti Dwi 
Published: October 2023

Kajian ini bertujuan menjelaskan pengaruh kompetensi, disiplin kerja serta gaya kepemimpinan terhadap kinerja guru MA YSPIS Gandrirojo, Kec. Sedan, Kab. Rembang. Sampel penelitian adalah sampel jenuh. Pengumpulan data pada penelitian ini dilakukan melalui kegiatan penyebaran kuesioner. Data yang diperoleh dari kuisioner dianalisis menggunakan regresi linier berganda. Hasil analisis data adalah kompetensi, disiplin kerja serta gaya kepemimpinan berpengaruh positif signifikan terhadap kinerja guru MA YSPIS Gandrirojo. Kemampuan menjelaskan variabel kompetensi, disiplin kerja serta gaya kepemimpinan terhadap variasi kinerja guru menunjukkan angka sebesar 46,1%, sedangkan 53,9% diungkap oleh variabel lain yang tidak termasuk dalam model ini.Kata Kunci: Kompetensi, Disiplin Kerja, Gaya Kepemimpinan, Kinerja Guru.
Comparisons of Static and Dynamic Analyses on Toppling Behaviors of Pile Driving Machinery, etc., on Soft Foundation
Authors: Toma Shouji , Seto Kenji , Chen Wai Fah 
Published: October 2023

Toppling accidents of heavy machinery such as pile drivers, cranes, high-altitude work vehicles, and jacks have been recurring in the world. In the past, researches focused to find the overturning moment which causes toppling. However, it is believed that the toppling accidents are related to structural stability issues, in which cases the accidents could possibly occur without any overturning moment. Accidents involving the structural instability are difficult to predict as the directions of load and deformation are different. This unpredictability is considered as a fundamental contributing factor to accidents recurring. Theoretical studies by static and dynamic analyses have been performed by the authors. It was found that not only static deformations but also dynamic inertial forces influence the increased risk of toppling. In the cases of structural instability, dynamic inertial force might amplify angular displacement beyond the critical stability angle, leading to rapid toppling and often resulting in significant disasters. Factors leading to toppling as a trigger include unexpected movement onto weak ground, increased magnitude of load and height, and greater ground incline. Taking those factors into consideration, this paper attempts to elucidate the mechanism of pile drivers' toppling by comparing static and dynamic analyses and providing essential information for preventing accidents. From both static and dynamic analyses, toppling behavior will be described in the load-deformation and the support stiffness-deformation relations. Furthermore, a role of temporal element is illustrated as a quick movement of the machines results in increased risk of toppling.

Received: 29 August 2023 | Revised: 8 October 2023 | Accepted: 17 October 2023

Conflicts of Interest
The authors declare that they have no conflicts of interest to this work.

Data Availability Statement
The data that supports the findings of this study is openly available with toma@hgu.jp, and would be shared upon request via email.
PERJUANGAN AGAMA, BANGSA DAN NUSA: KAJIAN TERHADAP TIGA AKHBAR MELAYU DI SARAWAK
Authors: NORDI ACHIE  
Published: October 2023

Kertas ini bertujuan mencerakin peranan kristalistik dan sumbangan vitalistik Fajar Sarawak (1930), dalam kancah zaman keangkuhan kolonialisme Barat dan sadisme dunia Melayu-Islam, merentasi garis zaman pancaroba yang besar iaitu Perang Dunia Pertama dan Kedua. Pada zaman inilah, muncul perjuangan keulamaan di Sarawak Darul Hana yang bangkit menyanggah terorisme Barat dan memercukan gagasan kemajuan Melayu-Islam, dengan pena dan tinta sebagai senjata perjuangan keulamaan. Persoalannya, mengapakah angkatan Fajar Sarawak teguh menggeluti zaman yang penuh berisiko dewasa itu? Menerusi wacana kerdil ini, penulis akan menggarap gagasan dan perjuangan Fajar Sarawak (1930) sembari menelusuri garis persamaan dan perbezaan penting (secara menyeluruh) dengan Utusan ASAS (1947-1948) dan Utusan Sarawak (1949-1950) secara komparatif, dalam konteks inklusivisi perjuangan keulamaan sezaman. Struktur wacana ini dibahagikan kepada tiga tema utama (ikuti pemerihalan selanjutnya). Bagaimanapun, aspek latar belakang masyarakat tidak disentuh di sini kerana ruangan yang terhad, malah keutamaan harus diberikan terhadap aspek pengisiannya. Begitu juga dengan kesan perjuangan akhbar Melayu, topik ini memerlukan kertas berasingan.

The purpose of this papar is to elaborate on the vital roles and core contributions of Fajar Sarawak (Malay newspapers in Sarawak), within the Western colonialism era in the Malay world, between the two world war eras (1941-1945). In this critical era, the Muslim scholars in Sarawak struggled firmly in insisting the so-called international terrorist aggression (Western colonialists) and devotionally boosted the ideas of Malay progression, via the intellectual discourse as well. The interesting question is why did they (as the ideas raised in the Malay newspapers) bravely opposed Western colonization, in spite of the different perspectives and approaches? The most essential aspect in this article will be focused on the Islamic struggle and aspirations of Fajar Sarawak, Utusan Asas, and Utusan Sarawak, in comparative perspectives as a whole.Hence, the structure of this article will be divided into three main themes. However, there are two aspects that will not be mentioned here; the background of the society in the respective eras and the impacts of the Malay newspapers struggle towards its nation as those topics need to be examined in other articles.
PERUBAHAN RITUAL SOGIT DALAM PEMBUKAAN KAWASAN TANAH BAHARU DI RANAU, SABAH: SATU TINJAUAN AWAL
Authors: MOHAMMAD FIRDAUS BIN HASMIN  , SYAMSUL AZIZUL MARINSAH  , SURAYA SINTANG  
Published: October 2023

Sogit adalah pampasan, ganti rugi ataupun denda yang dikenakan kepada individu yang melanggar norma atau kod etika adat. Sungguhpun begitu, amalan ini telah mengalami banyak perubahan terutamanya dalam tatacara pelaksanaan, rentetan daripada masyarakat Dusun yang telah banyak memeluk agama Islam. Oleh hal yang demikian, objektif kajian ini adalah untuk mengenal pasti perubahan rituual sogit dalam pembukaan kawasan tanah khususnya di daerah Ranau. Dalam kajian ini, pengkaji memfokuskan dua kampung sebagai lokasi kajian iaitu Kampung Purakogis dan Lipasu Lama, memandangkan masyarakat Dusun dalam kampung tersebut telah memeluk agama Islam Sehubungan dengan itu, kajian ini merupakan kajian kualitatif yang menggunakan metode pengumpulan data melalui kaedah temu bual semi berstruktur dan observasi. Hasil kajian mendapati, berlaku banyak perubahan dan sinkretisme di antara ajaran pra-Islam dengan ajaran Islam dalam amalan sogit pembukaan kawasan tanah baharu.

Sogit is a reparation, compensation or a punishment made upon an individual who violates norms and customs etiquette code. However, this particular tradition has undergone drastic changes especially in its implementation. This scenario is mainly due to most of the Dusuns who have started to adapt Islam as their religion. Therefore, the main objectives of this research is to identify the changes of sogit tradition in an opening of a vacant land in Ranau. In this research, the researcher focuses on two villages as their location of study, which is Kampung Purakogis and Lipasu Lama. In addition, this research is adapting qualitative approach as their research method where data collection was made through semi structured interviews and observations. Research finding shows that there are many changes and synchronism between Islam’s early teachings and the teaching of Islam itself in an agricultural land opening tradition.