P-427. Prevalence of Healthcare-Associated Infections: 2023 Point Prevalence Survey in 218 U.S. Acute Care Hospitals
Authors: Chea Nora , Eure Taniece R , Ramirez Rebecca Alkis , Nadle Joelle , Lee Jane E , Lehmann Monica , Sardenga Lyndzie , Czaja Christopher A , Johnston Helen , Kellogg Melissa , Emanuel Catherine E , Cilwick Alana , Correa Maria , Maloney Meghan , Ray Susan M , Howard-Anderson Jessica R , Carswell Stacy , Perlmutter Rebecca , Marceaux-Galli Kaytlynn , Mahoehney J P , Lynfield Ruth , Sievers Marla , Cline Cory , Judson Melissa , Gorman Donita C , Dumyati Ghinwa , Hurley Christine , Keller Elizabeth , Walsh Marissa , Licherdell Erin , Tellerman Julia , Felsen Christina B , Pierce Rebecca , Ocampo Valerie Leigh S , Samper Monika E , Hires Kimberly A , Adrian Lauren T , Tammer Roza , Zhang Alexia Y , Hiratzka Shannon , Dusko Angela , Wilson Christopher , Harriott Melphine , Muleta Daniel , Morrell Casey L , Nevels Darryl C , Adre Cullen , Magill Shelley , Grigg Cheri 
Published: January 2025

Abstract

Background
The Centers for Disease Control and Prevention (CDC) conducted point prevalence surveys in U.S. acute care hospitals in 2011 and 2015 to determine the prevalence and distribution of healthcare-associated infections (HAIs) and complement data reported to the CDC’s National Healthcare Safety Network (NHSN). HAI prevalence in hospitals was 4.0% in 2011 and 3.2% in 2015. We repeated the survey in 2023 to reassess hospital HAI prevalence and distribution. Here, we present the results of our preliminary analysis of the 2023 survey data.

Methods
Emerging Infections Program (EIP) sites in 10 states recruited up to 25 hospitals each, prioritizing hospitals that participated in the 2011 or 2015 survey. Each hospital selected a survey day between May 1 and September 30, 2023. Trained EIP staff reviewed medical records of patients randomly selected from the inpatient census on the survey day. Data collected included patient demographics, clinical characteristics, medical devices, hospital locations, and HAIs based on 2023 NHSN definitions. We described the characteristics of patients included in the survey and the percentage with HAIs.

Results
Of 13,654 patients in 218 hospitals, 357 (2.6%) had 392 HAIs. Compared to patients without an HAI, patients with HAIs were more frequently located in large hospitals, in critical care units, hospitalized ≥7 days on the survey date, and were more likely to have a central line, urinary catheter, or be on a ventilator on the survey date (Table). Among the 392 HAIs, 101 (25.8%) were pneumonia, 82 (20.9%) surgical site infection, 57 (14.5%) gastrointestinal infection, 47 (12.0%) bloodstream infection, 35 (8.9%) urinary tract infection, and 70 (17.9%) other HAI types. Most HAIs (241, 61.5%) were not associated with devices or procedures (Figure).

Conclusion
HAI prevalence in acute care hospitals in 2023 was low. Almost two-thirds of HAIs were not associated with devices or procedures. These findings emphasize the need for continued infection prevention and control efforts in hospitals for all types of HAIs including those not associated with devices or procedures.

Disclosures
Meghan Maloney, MPH, Pfizer Global R&D: Former employee, separated in 2009. I do have a retirement entitlement which I do not actively manage/no stock options. PGRD offers periodic buy outs