bluuebunny/crossref_metadata_2025_split huggingface dataset:
Movements and habitat use of a nursery area by a wide-ranging species of shark in the southern Caribbean
Authors: Tavares Rafael , Kresge Colby D. , Wetherbee Bradley M. 
Published: January 2024

Abstract
Use of a small tropical nursery in the Los Roques Archipelago by lemon sharks (Negaprion brevirostris) was investigated using acoustic telemetry. Twelve lemon sharks (six female, six male, three each of age classes 0+, 1+, and 2+) were tracked between February 2014 and August 2015 in the Sebastopol Lagoon. Sharks were strongly site attached and remained in the lagoon for the duration of the study. Age 0+ individuals largely restricted their movements within the innermost area of the lagoon in shallow water (< 1 m), over muddy substrate and along mangrove-lined shores. Ages 1+ and 2+ sharks ranged further, in deeper water, over a wider range of substrates and more frequently to areas near the lagoon entrance. Activity space (home range = 95% kernel utilization densities - KUD) was 0.42, 1.11 and 1.15 km2 for age 0+, 1+ and 2+ sharks respectively. Core area (50% KUD) was 0.13, 0.33 and 0.35 km2 for age 0+, 1+ and 2+ sharks respectively. MCP overlap between ages 1+ and 2+ was 89%, in contrast to smaller overlap between ages 0+ and 1+ (40%) and 0+ and 2+ (43%). Abundance of potential prey was greatest along mangroves fringes, decreasing from the innermost lagoon to entrance. Space use of lemon sharks within nurseries of variable characteristics illustrates a consistent balancing of selective pressures on predator avoidance and prey acquisition among inconsistent nursery habitats. Understanding nursery area use aids informed management of lemon shark populations and incorporation of species-wide life history traits for sustainable management practices.
Dissecting causal relationships between primary biliary cholangitis and extrahepatic autoimmune diseases based on Mendelian randomization
Authors: Ma Gang , Yang Jiaqi , Wang Xingguo , Xia Erzhuo , Yu Jiahao , Zhang Miao , Hu Yinan , Ma Shuoyi , Zhou Xia , Fan Qingling , Han Ying , Wang Jingbo 
Published: January 2024

Abstract
Background
As an autoimmune disease, up to 73% of patients with primary biliary cholangitis (PBC) have a combination of extrahepatic autoimmune diseases (EHAIDs); however, the causal relationship between PBC and EHAIDs is unclear.
Methods
The genome-wide association analyses provided 14 GWAS data for PBC and EHAIDs, and bidirectional, two-sample MR analyses were performed to examine the relationship between PBC and EHAIDs.
Results
The analysis using MR provides a strong and meaningful estimation of the bidirectional correlation between PBC and 7 EHAIDs: rheumatoid arthritis, systemic lupus erythematosus, Sjögren's syndrome, systemic sclerosis, autoimmune hypothyroidism, inflammatory bowel disease and ulcerative colitis of its types. In addition, PBC increases the risk of autoimmune thyroid diseases such as autoimmune hyperthyroidism and Graves' disease, as well as multiple sclerosis and psoriasis. Additionally, PBC is identified as a risk factor for Crohn's disease and Celiac disease.
Conclusion
Based on genetic evidence, there may be connections between PBC and specific EHAIDs: not all coexisting EHAIDs induce PBC, and vice versa. This underscores the significance of prioritizing PBC in clinical practice. Additionally, if any liver function abnormalities are observed during treatment or with EHAIDs, it is crucial to consider the possibility of comorbid PBC.
Realization of strong microwave absorption characteristics of Gd 5 Si 2 Ge 2 nanoparticles with materials data-driven discovery
Authors: Bora Pritom J. , Mahanta Bibhusita , Gupta Shalabh , Ramamurthy Praveen C. , Hadimani Ravi L. 
Published: January 2024

Abstract
In this study, we utilized a materials data-driven approach to investigate the microwave absorption characteristics of Gd5Si2Ge2 nanocomposites. These results suggests that Gd5Si2Ge2 nanocomposites possess highly efficient microwave absorption properties. It was observed that varying the loading of the Gd5Si2Ge2 nanoparticles in a polymer matrix, such as polydimethylsiloxane (PDMS), resulted in changes in reflection loss (RL). However, it was also found that simply increasing the loading of the Gd5Si2Ge2 nanoparticles in PDMS did not improve RL performance. To optimize the RL performance, we employed an electromagnetic data-driven methodology. Obtained results predict a remarkable RL of ≤ -60 dB for a composite containing 60 wt% Gd5Si2Ge2 nanoparticles loaded PDMS in the frequency range 8.2–18 GHz. This prediction was supported by experimental data, which showed a minimum RL value of -57 dB with multiple RL≤-10 dB bandwidth. These findings validate the proposed proof of concept of utilizing data-driven methodology to obtain broadband and robust microwave absorption characteristics in Gd5Si2Ge2 nanocomposites.
Psychometric properties of dysphagia handicap index scale for older adults with oropharyngeal dysphagia in China
Authors: Li Laiyou , Ning Sun , LI Qianru , Fan Chaoyan , Li Hongyu , Yang Shuang , Li Yun 
Published: January 2024

Abstract
Background
Oropharyngeal dysphagiaare was important for older adults in the West, but they have not received enough attention from China. This study evaluated the psychometric properties of a oropharyngeal dysphagia evaluation instrument for older Chinese adults .
Methods
A total of 600 older adults were recruited from five nursing homes in one city to complete a 25-item scale. The reliability and validity of the scale was evaluated using multiple assessments, including a content validity assessment, Cronbach’s alpha, an item-to-total correlation test, and exploratory factor analysis.
Results
The scale was divided into three sub-sections:physical(items 1p–9p), functional (items 1f–9f), emotional(items 1e–7e). Cronbach’s alpha was 0.97 for the whole scale and ranged from 0.89 to 0.94 for the four sub-scales. The item-to-total correlation coefficients for the four sub-scales were between 0.63 and 0.92, and the test-retest correlation coefficient was 0.87.
Conclusions
Our results validated the reliability and validity of a scale designed to measure the quality of long-term care services for older Chinese adults with dementia.
Liquefaction Phenomenon Identification from post-Pohang Earthquake 2017, South Korea based Integrated SAR and optical imagery data using a machine-learning approach
Authors: Fadhillah Muhammad Fulki , Hakim Wahyu Luqmanul , Park Sung-Jae , Lee Chang-Wook 
Published: January 2024

Abstract

An interesting liquefaction phenomenon occurred after the 5.6 Mw Pohang earthquake on November 15, 2017. Liquefaction changes soil density due to earthquake vibrations, which in turn causes water to rise and merge with solid soil. Remote sensing data, particularly those obtained with differential interferometric synthetic aperture radar (DInSAR), can be used to determine surface changes and changes in soil moisture. This study used data from the Sentinel-1 C-band from 2016–2020. In addition, optical satellite data were used to determine the changes in water content and soil moisture that occurred after the Pohang earthquake. A combination of spectral bands sensitive to changes in water content were used based on Sentinel-2 and Landsat-8 data. This was correlated with changes in water content, which were analyzed using optical satellite and DInSAR data with a spatial accuracy of 60–80% in comparison with field data. Moreover, the liquefaction susceptibility map has been generated using convolutional neural network with the AUC value is 0.813. However, this research was the initial research to determine the potential of liquefaction in the future based on 2017 Pohang earthquake, and the results can be the reference to improve our understanding of this liquefaction phenomenon.
HACD: A Hybrid Abusive Content Detector based on Convolutional Neural Network and Long Short-Term Memory
Authors: ABDOU Aziz L. NGOU NJIKAM , TAGNE Elie FUTE 
Published: January 2024

Abstract
Social media platforms have recently recorded an increase in users worldwide -the numbers progressively rising every year. Yet this has unfortunately resulted into an increase of offensive content online- including hate speech conveying derogatory remarks about individuals on social platforms ultimately affecting law enforcement measures within communities leading occasionally to loss of human lives or property-damages. Consequently, identifying such problematic material requires extensive research efforts within machine learning and natural language processing fields hence prompting important questions on prevailing solution models. In response, our proposed solution through this paper lies with hybrid models that will combine Convolutional Neural networks (CNN) alongside Long Short-Term Memory (LSTM) techniques to accurately classify textual contents into three distinct groups: hateful/abusive/or neutral categories. As we provide comparability studies between our novel technique against pre-existing LSTM-based models predominantly cited in existing literatures, promising results were obtained in terms of accuracy, precision, recall and F-1 score. Our experiment used the widely regarded "Data Science dataset" (Datascisteven), accepted as a reliable source for research studies.
Drug Therapy Problems among Older Adults in Nursing Home with Integration of Medical and Old-age Care: A Cross-Sectional Study
Authors: Liang Zhuoru , Zheng Guimei , Qin Sibei , Xu Xiayan , Wang Zhenxing , Ye Chenli , Liu Jiang , Liu Jing , Cao Weiling 
Published: January 2024

Abstract
Background: As the aging process speeds up in China, drug therapy problems (DTPs) for older adults (60 years and older) in nursing homes have become serious. “Integration of medical and old-age care” has been introduced to nursing homes, however, whether it has an impact on DTPs is unknown. This study aimed to determine the frequency and type of DTPs among older adults in a nursing home with the integration of medical and old-age care.
Methods: This is an observational and cross-sectional study. Drug use and DTPs of older adults were conducted in June 2023 from a nursing home with integration of medical and old-age care located in Shenzhen, Guangdong province of China.
Results: A total of 249 older adults participated in this study. The mean age was 85.88 years, 62.4% were women. Medications used per person was 4 (SD=2.43). Polypharmacy was recorded in 30.12% of the older adults, and excessive polypharmacy in 3.21%. A total of 73 DTPs were identified, with an average of 0.25 DTPs per older adult. The most frequent DTP was nonadherence or noncompliance (n=30), followed by adverse drug reactions (n=14).
Conclusions: The DTPs were lower among older adults in this medical and old-age care integrated nursing home than previously reported in traditional care nursing homes, however, there is still room for improvement. To reduce DTPs in nursing homes older adults, pharmacists should be introduced, and a regular evaluation of DTPs is also necessary.
Efficacy and Acceptability of Self-Collected Medical Grade Tampon as a Novel Vaginal Sample Collection Tool for the Detection of HPV and STIs
Authors: Milanova Valentina , Lazarova Iva , Mihaylova Kalina , Gomes Michelle , Georgieva Teodora , Multmeier Jan 
Published: January 2024

Abstract
Objective: Cervical cancer remains a significant health concern, particularly in low-income and middle-income countries (LMICs). This study aims to compare the efficacy and suitability of a self-collected tampon for the detection of human papillomavirus (HPV) and sexually transmitted infections (STIs) using qualitative TMA-based assays (Transcription Mediated Amplification; APTIMA ® HPV, APTIMA ® Combo 2 (CT/NG; AC2 from now on) and APTIMA ® Bacterial Vaginosis (BV from now on). Additionally, we assess the acceptability of tampons as a self-collection tool.
Methods: A cohort of 75 female participants aged 18-54 years was recruited through female-focused social networks. Participants provided informed consent and underwent both Health Care Workers (HCW-collected) and self-collected sample collection using the Daye Diagnostic Tampon. Samples were stored in ThinPrep Vials (TP Vial) or Aptima ® Multitest Swab Collection Kit (APTIMA ®) solutions. HPV and STI testing were performed using TMA-based assay on the fully automated Panther ® Platform. Acceptability was assessed through a questionnaire with Likert-scale responses.
Results: The study involved 60 participants who completed the study (80% of recruited participants). The self-collected tampons showed sensitivity and specificity of 66.67% and 90.74% (when rinsed in TP Vial) and 83.33% and 85.42% (when rinsed in APTIMA ®) for HPV detection, respectively. For bacterial vaginosis (BV) detection, the tampons exhibited sensitivity and specificity of 100.0% and 96.43% (TP Vial) and 88.89% and 98.04% (APTIMA), respectively. For detection of chlamydia and gonorrhoea (AC2), the sensitivity and specificity were 100.00% and 100.0% (TP Vial) and 100.00% and 98.31% (APTIMA), respectively. Participants expressed a preference for tampon self-collection over HCW-collected swabs (90%).
Conclusion: Self-collected tampons demonstrated promising diagnostic accuracy to HCW-collected swabs for HPV and STI detection. The tampon self-collection method was well-accepted and preferred by participants, suggesting its potential as an alternative screening tool, particularly in low-resource settings. Further research with larger and more diverse populations is recommended to validate these findings and inform tampon-based self-collection programs for cervical cancer screening. Randomised controlled trials and comparisons with gold standard methods would enhance validation.
Gender and spatial variation of loneliness among adolescents in three South Asia countries: Prevalence and its correlates
Authors: Hasan Md. Khalid , Uddin Helal , Younos Tahmina Bintay , Mukta Nur A Habiba 
Published: January 2024

Abstract
Background The study aimed to explore the gender and spatial variation of loneliness and identify its correlates among in-school adolescents in three South Asian countries.Methods We used Afghanistan, Bangladesh, and Pakistan's latest Global School-based Student Health Survey (GSHS) datasets. A total of 8089 adolescent data were analyzed using multiple logistic regression models after controlling socio-demographic variables. We used STATA 14 to perform the analyses.Results The prevalence of loneliness among male respondents was 12.28 [95% CI: 11.3–13.3] and 18.1 [95% CI: 16.8–19.5] in females. Afghan adolescents' prevalence of loneliness was the height (34.8%), followed by Pakistani (11.4%) and Bangladeshi adolescents (8.4%). For both genders (male and female), loneliness was higher among the adolescents who were school truants, bullied, involved in physical fights, and experienced physical attacks. In addition, both male and female adolescents with anxiety-induced sleep disturbance, current tobacco users, and suicidal ideation had significantly higher odds of loneliness than their counterparts. Moreover, several poor mental health conditions, such as anxiety-induced sleep disturbance, bullying, suicidal ideation, and suicide plan, were significantly associated with higher odds of loneliness among in-school adolescents in Afghanistan, Bangladesh, and Pakistan. Besides, respondents involved in physical fights were more likely to be lonely.Conclusion We explored the gender and spatial variation of loneliness among adolescents in three South Asian countries and found several similarities and differences in prevalence and correlates of loneliness between various sub-groups. Gender-sensitive and spatial target-oriented policies and interventions should be developed and implemented urgently to reduce the prevalence of adolescent loneliness in these three countries. More studies are also recommended to explore the relationship between loneliness and socio-economic, environmental, and health-behavioral factors among adolescents in these countries.
The impact of dose rate on responses of human lens epithelial cells to ionizing irradiation
Authors: Matsuya Yusuke , Sato Tatsuhiko , Yachi Yoshie , Date Hiroyuki , Hamada Nobuyuki 
Published: January 2024

Abstract
The knowledge on responses of human lens epithelial cells (HLECs) to ionizing radiation exposure is important to understand mechanisms of radiation cataracts that are of concern in the field of radiation protection and radiation therapy. However, biological effects in HLECs following protracted exposure have not yet fully been explored. Here, we investigated the temporal kinetics of γ-H2AX foci as a marker for DNA double-strand breaks (DSBs) and cell survival in HLECs after exposure to photon beams at various dose rates, compared to those in human lung fibroblasts (WI-38). In parallel, we quantified the recovery for DSBs and cell survival using a biophysical model. The study revealed that HLECs have a lower DSB repair rate than WI-38 cells. There is no significant impact of dose rate on cell survival in both cell lines in the dose-rate range of 0.033–1.82 Gy/min. In contrast, the experimental residual γ-H2AX foci showed inverse dose rate effects (IDREs) compared to the model prediction, highlighting the importance of the IDREs in evaluating radiation effects on the ocular lens.
Identifying Factors Associated with Post-Traumatic brain injury Depression: The Role of Inflammatory Markers
Authors: Yang Zhen , 王 德龙 , Liu Yang , Yan Hongwang , Cheng Yuanchi 
Published: January 2024

Abstract
Background
Depression is a common emotional and psychiatric complication of traumatic brain injury (TBI) that has significant negative impacts on patient recovery. Despite the importance of identifying and treating depression in TBI patients, there is currently no simple and standardized system available for assessing the likelihood of post-TBI depression. In this study we are aim to explore the clinical value of peripheral blood inflammatory markers in predicting mental disorders after TBI.
Methods
A total of 67 TBI patients in this study were included and divided them into Group A (depression group) or Group B (non-depression group) based on the presence or absence of concomitant psychiatric disorders. We collected relevant clinical data and inflammatory markers from both groups to identify factors influencing post-TBI depression and analyzed their diagnostic efficacy and correlations.
Results
The overall prevalence of mental disorders among TBI patients was found to be 64.18% at the three-month follow-up after injury. Our study revealed that intracranial infection was an independent factor influencing the occurrence of post-TBI depression (OR = 19.873, 95%CI = 6.721 ~ 58.764, P = 0.001). Patients who developed post-TBI depression had significantly higher levels of white blood cells(WBCs), neutrophil percentage, C-reactive protein (CRP), and monocyte levels compared to non-depressed TBI patients. Additionally, WBCs (Pearson = 0.735,P = 0.001), neutrophil percentage (Pearson = 0.742, P = 0.001), and CRP (Pearson = 0.556, P = 0.001) levels were positively correlated with depression severity in TBI patients.
Conclusions
Our findings suggest a high prevalence of post-TBI depression and highlight peripheral inflammatory markers such as WBCs, neutrophil percentage, and CRP levels as potential early diagnostic indicators for this condition. Identifying these factors can facilitate early diagnosis and intervention for post-TBI depression, improving patient outcomes. This study provides evidence for clinicians to develop effective treatment strategies for post-TBI depression and advance our understanding of its mechanisms.
Minor impact of anastomotic leakage in anterior resection for rectal cancer on long-term male urinary and sexual function
Authors: Rutegård Martin , Jutesten Henrik , Buchwald Pamela , Angenete Eva , Lydrup Marie-Louise 
Published: January 2024

Abstract
Purpose
Anastomotic leakage after anterior resection for rectal cancer induces bowel dysfunction, but the influence on urinary and sexual function is largely unknown. This cross-sectional cohort study evaluated long-term effect of anastomotic leakage on urinary and sexual function in male patients.
Methods
Patients operated with anterior resection for rectal cancer in 15 Swedish hospitals 2007–2013 were identified. Anastomotic leakage, and other clinical variables were retrieved from the Swedish Colorectal Cancer Registry and medical records. Urinary and sexual dysfunction were evaluated at 4 to 11 years after surgery using International Prostate Symptom Score, International Index of Erectile Function, and European Organization for the Research and Treatment of Cancer Quality of Life Questionnaire CR29. The effect of anastomotic leakage on average scores of urinary and sexual dysfunction was evaluated as a primary outcome, and the single items permanent urinary catheter and sexual inactivity as secondary outcomes. The association of anastomotic leakage and functional outcomes was analyzed using regression models with adjustment for confounders.
Results
After a median follow-up of 84 months (interquartile range: 67–110), 379 out of 864 eligible men were included. Fifty-nine (16%) patients had anastomotic leakage. Urinary incontinence was more common in the leakage group, with an adjusted mean score difference measured by EORTC QLQ ColoRectal–29 of 8.69 (95% confidence interval: 0.72–16.67). The higher risks of urinary frequency, permanent urinary catheter and sexual inactivity did not reach significance.
Conclusion
Anastomotic leakage after anterior resection had a minor negative impact on urinary and sexual function in men.
Biodegradable Poly(ethylene glycol-glycerol-itaconate-sebacate) Copolyester Elastomer with Significantly Reinforced Mechanical Properties by in-situ Construction of Bacterial Cellulose Interpenetrating Network
Authors: Tang Lisheng , Jin Yuanyuan , He Xiaoyan , Huang Ran 
Published: January 2024

Abstract
To address the concern that biodegradable elastomers are environmental-friendly but usually associated with poor properties for practical utilization, we report a star-crosslinked poly(ethylene glycol-glycerol-itaconate-sebacate) (PEGIS) elastomer synthesized by esterification, polycondensation and UV curing, and reinforced by Bacterial Cellulose (BC). The interpenetrating network of primary BC backbone and vulcanized elastomer is achieved by the “in-situ secondary network construction” strategy. With the well dispersion of BC without agglomeration, the mechanical properties of PEGIS are significantly enhanced in tensile strength, Young's modulus and elongation at break. The reinforcement strategy is demonstrated to be efficient and offers a route to the development of biodegradable elastomers for a variety of applications in the future.
Novel Synthesis of New Triazine Sulfonamides with Antitumor, Antimicrobial and Anti-SARS-CoV-2 Activities
Authors: Mohamed-Ezzat Reham A. , elgemeie galal 
Published: January 2024

Abstract
Novel approach for synthesizing triazine sulfonamide derivatives is accomplished via reacting the sulfaguanidine derivatives with
N-cyanodithioiminocarbonate. Further reaction of the novel triazine sulfonamide analogues were reacted with various secondary amines, anilines and 2-aminothiazole to generate various substituted triazine sulfonamide analogues of promising broad spectrum activities. The in vitro anti-proliferative activities of most of the novel compounds were evaluated on the NCI-60 cell line panel. The antifungal and antibacterial activities of the compounds were also estimated. The antiviral activity against SARS COV-2 virus was performed to evaluate the half-maximal cytotoxic concentration (CC50) and inhibitory concentration 50 (IC50) of a representative compound from the novel triazine sulfonamide category.