bluuebunny/crossref_metadata_2025_split huggingface dataset:
Clinical and diagnostic imaging profile of three anterior segment dysgenesis disorders presenting with infantile corneal opacities
Authors: Kaginalkar Ananya , Tandon Radhika , Vanathi M. , Gupta Noopur , Gupta Viney , Sen Seema , Kashyap Seema , Sharma Arundhati 
Published: December 2023

PURPOSE:
To describe three anterior segment dysgenesis disorders with infantile corneal opacities, namely, congenital hereditary endothelial dystrophy (CHED), primary congenital glaucoma (PCG), and Peters anomaly (PA) in terms of clinical characteristics, histopathology, genetic association, and diagnostic imaging profiles using imaging modalities such as ultrasound biomicroscopy (UBM) and microscope-integrated intraoperative optical coherence tomography (i-OCT).

MATERIALS AND METHODS:
Seventy-four eyes with 22 eyes of CHED, 28 eyes of PA, and 24 eyes of PCG were clinically evaluated and underwent imaging using UBM and i-OCT. Corneal buttons of 16 operated patients underwent histopathological analysis, while genetic analysis was done in 23 patients using whole-exome sequencing.

RESULTS:
Corneal diameters (CD) and UBM parameters like anterior chamber depth (ACD), iris thickness (IT), and ciliary body (CB) thickness revealed a statistically significant difference between the three categories. In PA, 9 eyes had a third rare phenotype with only a posterior corneal defect with no iris adhesions. Genetic mutations were seen in all tested patients with CHED, in 83.3% of patients with PCG, and in 80% of patients with the third type of PA. i-OCT helped in the characterization of corneal opacity, identification of posterior corneal defects, iridocorneal adhesions, and contour of Descemet’s membrane.

CONCLUSION:
Overlapping phenotypes of the above disorders cause a diagnostic dilemma and parameters like CDs, UBM ACD, IT, and CB thickness help differentiate between them. i-OCT can help in classifying the diseases in a high resolution, non-contact manner, and can better delineate corneal characteristics. The rare third type of PA phenotype may have a genetic association.
Merging Minds and Machines: The Role of Advancing AI in Robotics
Authors: Prakash Nishtha , Atiq Areeba , Shahid Mohammad , Rani Jyoti , Dikshit Srishti 
Published: December 2023

The relentless pursuit of creating intelligent robotic systems has led to a symbiotic relationship between human inventiveness and artificial intelligence (AI). Artificial intelligence is a theory. It is the development of computer systems that are able to perform tasks that would require human intelligence. This abstract explores the pivotal role that AI plays in advancing the capabilities and applications of robotic systems. The integration of AI algorithms and machine learning techniques has launched robotics beyond mere automation, enabling machines to modify, alter, adjust, learn, and interact with the world in ways previously deemed science fiction. Design fictions that vividly imagines future scenarios of AI or robotics in use offer a means both to explain and query the technological possibilities. Examples of these tasks are visual perception, speech recognition, decision-making, and translation between languages. The three key dimensions of AI’s role in robotics are Cognitive Augmentation, Human-Robot Collaboration, and Autonomous Intelligence. The abstract also discusses the societal implications of this AI-driven advancement in robotic systems, including ethical considerations, job market impacts, and the democratization of access to advanced technology. The convergence of human intellect and artificial intelligence in robotics marks a transformative era where machines become not just tools, but companions, collaborators, and cognitive extensions of human capabilities. Researchers are taking inspiration from the brain and considering alternative architectures in which networks of artificial neurons and synapses process information with high speed and adaptive learning capabilities in an energy-efficient, scalable manner. The indispensable role of AI in shaping the future of robotic systems and bridging the gap between human potential and machine capabilities is highlighted. The major impact of this synergy reverberates across industries, promising the world where robots become not just mechanical contraptions / defective apparatus but intelligent partners in our journey of progress.
Inserção Social, Democracia e Produção de Conhecimento
Authors: Rúpia Júnior Bento José 
Published: December 2023

Resumo: Este artigo é oriundo da conferência realizada pelo professor Bento José Rúpia Junior no XIV Congresso Nacional de Pesquisa em Educação (COPED), que ocorreu entre os dias 13 e 16 de junho de 2023 na Universidade Estadual de Montes Claros (Unimontes), Congresso foi organizado pelas professoras e professores do Programa de Pós-Graduação em Educação (PPGE) da Unimontes, e do Departamento de Métodos e Técnicas Educacionais (DMTE) da mesma instituição. A conferência, que deu origem ao artigo, intitulada de Inserção Social, Democracia e Produção de Conhecimento, foi desenvolvida na abertura do evento supracitado, pelo convidado internacional do COPED 2023, Bento José Rúpia Junior, que é professor associado da Universidade Pedagógica de Moçambique e Diretor da Faculdade de Ciências Sociais e Filosofia de Maputo-Moçambique.
Yumurta Tavuklarında Rasyona Fitobiyotik ve Probiyotik İlavesinin Performans ve Yumurta Kalite Özelliklerine Etkisi
Authors: GÖKMEN Seyit Ahmet , CUFADAR Yusuf , CURABAY Barışcan 
Published: December 2023

Bu çalışmada yumurtacı tavuk rasyonlarına fitobiyotik ve probiyotiğin ayrı ayrı ve birlikte ilavesinin performans, yumurta iç ve dış kalite parametreleri üzerine etkilerini belirlenmesi amaçlanmıştır. Çalışma 41 haftalık yaştaki toplam 108 adet yumurta tavuğunda (Tinted) 12 hafta süreyle yürütülmüştür. Denemede kontrol, 500 mg/kg seviyesinde fitobiyotik, 500 mg/kg seviyesinde probiyotik ve 250 mg/kg seviyesinde fitobiyotik +250 mg/kg seviyesinde probiyotik ilave edilen 4 farklı rasyon, 9 tekerrürlü olarak her bir alt grupta 3 tavuk olacak şekilde toplam 36 alt grupta denenmiştir.
Rasyona fitobiyotik, probiyotik ve kombinasyonlarının ilavesi performans parametrelerini istatistiki açıdan önemli olarak etkilememiştir (P>0.05). Çalışmada fitobiyotik, probiyotik ve karışımlarını içeren muamelelerin yumurta sarı rengi a* değeri dışındaki diğer yumurta iç ve dış kalite parametrelerine etkisi önemsiz olmuştur (P>0.05). Rasyona tek başına probiyotik ilavesi yumurta sarı rengi a* değerini diğer muamelelere göre önemli derecede arttırmıştır (P
ON THE QUESTION OF THE IMPLEMENTATION OF THE CONSTITUTIONAL AND LEGAL FOUNDATIONS WITHIN THE FRAMEWORK OF THE INSTITUTE OF INSOLVENCY (BANKRUPTCY) IN THE RUSSIAN FEDERATION
Authors: Павлов С.Ю. , Шайдуллин В.Ф. 
Published: December 2023

Рассмотрена сущность института несостоятельности (банкротства) в разрезе соответствия конституционным основам в Российской Федерации. Актуальность тематики исследования обуславливается необходимостью в оптимизации института несостоятельности (банкротства) a posteriori, а также тем положением, что судебные процедуры банкротства граждан производятся с учетом положений конституционно-правовых основ. Надлежащая регламентация финансовых правоотношений, в том числе и отдельных аспектов регулирования процедуры несостоятельности (банкротства), представляется ключевым направлением деятельности государства по обеспечению конституционных положений. В научной статье, авторы проводят анализ некоторых аспектов юридической регламентации сущности института несостоятельности (банкротства), определяют соответствие процедурного порядка банкротства действующим конституционно-правовым основам в Российской Федерации, производят сопоставление между теоретической и практической сторонами данного вопроса.
Within the framework of these research studies, the essence of the institute of insolvency (bankruptcy) was considered in the context of compliance with the constitutional foundations in the Russian Federation, enshrined in the Constitution of the Russian Federation. The relevance of the research topic is determined by the need to optimize the institution of insolvency (bankruptcy) a posteriori, as well as the provision that judicial procedures for bankruptcy of citizens are carried out taking into account the provisions of the constitutional and legal framework. Proper regulation of financial legal relations, including certain aspects of the regulation of the insolvency (bankruptcy) procedure, is a key area of the state’s activity to ensure constitutional provisions. Within the framework of this scientific article, the authors analyze some aspects of the legal regulation of the essence of the institution of insolvency (bankruptcy), determine the compliance of the bankruptcy procedure with the current constitutional and legal foundations in the Russian Federation, make a comparison between the theoretical and practical sides of this issue.
TERAPIA DE ANTICOAGULAÇÃO EM RECÉM-NASCIDOS: UMA REVISÃO INTEGRATIVA
Authors: Silva José Vitor Mota de Moura , Moita Antonino Neto Coelho , Hasegawa Luciana Eda Maximiano , Nunes Mouta Alba Angélica , Lopes Matheus Orany Abreu Sousa , Gomes Samuel Abreu , Vasconcelos Alysson Leunam Meneses , Mesquita Adriano Joab Meneses 
Published: December 2023

Os recém-nascidos (RN) tem o sistema de coagulação imaturo, só se regulariza no primeiro ano de vida, podendo ocorrer de forma tardia em cardiopatas. A necessidade do uso de terapia anticoagulante em RN vem aumentando nos últimos anos, mas ainda existem poucos estudos voltados para a população pediátrica, o que dificulta a padronização da droga de escolha e o ajuste da posologia. Trata-se de uma revisão de literatura integrativa sobre a terapia de anticoagulação em recém-nascidos. A trombose é um efeito de rara ocorrência em pacientes jovens, o grupo mais associado com esse evento (dentre os jovens) são os recém-nascidos. Dentre as drogas com ação anticoagulante, a mais utilizada nessa faixa etária é a heparina, por ser o fármaco que possui mais estudos comprovando a melhor ação e segurança dessas drogas. No entanto, ainda existe uma dificuldade no uso dessa droga, porque elas atuam se ligando as proteínas plasmáticas, e estas são reduzidas nos recém-nascidos. A heparina está fortemente associada a efeitos adversos na população pediátrica, por isso diversos estudos vêm sendo conduzidos para avaliar a eficácia do uso de anticoagulantes orais, como a varfarina e a dabigatrana. Existem poucos estudos que abordem a anticoagulação na pediatria, e os estudos que existem sobre o tema abordam apenas a heparina. Existem estudos em andamento que utilizam os fármacos orais e que trazem expectativas da liberação do uso dessas drogas para a faixa etária pediátrica nos próximos anos.
PENGARUH METODE SGD TERHADAP MOTIVASI BELAJAR PAI SISWA KELAS X SMA PLUS YADAJA PENUNTUT
Authors: Haris Yogi Sopian , Zulkifli Muh , Arifin Zainul 
Published: December 2023

Penelitian ini bertujuan untuk menginvestigasi pengaruh Small group discussion terhadap motivasi belajar Pendidikan Agama Islam pada siswa kelas X di SMA Plus YADAJA selama tahun pelajaran 2022/2023. Small group discussion dianggap sebagai salah satu pendekatan pembelajaran yang dapat meningkatkan keterlibatan siswa dan motivasi mereka dalam pembelajaran PAI. Penelitian ini menggunakan desain eksperimen semu dengan kelompok kontrol. Sampel penelitian terdiri dari dua kelompok: kelompok eksperimen yang menerapkan Small group discussion dalam pembelajaran PAI dan kelompok kontrol yang menggunakan metode konvensional. Data dikumpulkan melalui Angket/kuesioner yang mengukur tingkat motivasi belajar siswa sebelum dan setelah perlakuan. Hasil penelitian menunjukkan bahwa penggunaan Small group discussion secara signifikan meningkatkan motivasi belajar siswa dalam mata pelajaran PAI. Hal ini dapat di lihat nilai taraf signifikansi (2-tailed) yaitu 0,039 < 0,05 artinya H0 ditolak dan Ha diterima. Juga dapat di lihat dari Perbandingan nilai r hitung dengan r table yaitu 2,237 > 0,632 artinya H0 ditolak dan Ha di terima yaitu Ada Pengaruh Small Group Discousioun Terhadap Motivasi Belajar Siswa Kelas X SMA Plus YADAJA Penuntut. Berdasarkan hasil pengolahan data diatas diperoleh nilai Mean Different nya 8, 600 nilainya positif artinya pengaruh yang di timbulkan oleh small group discousioun terhadap motivasi belajar bersifat positif.
Marine carbohydrates in Arctic aerosol particles and fog – diversity of oceanic sources and atmospheric transformations
Authors: Zeppenfeld Sebastian , van Pinxteren Manuela , Hartmann Markus , Zeising Moritz , Bracher Astrid , Herrmann Hartmut 
Published: December 2023

Abstract. Carbohydrates, originating from marine microorganisms, enter the atmosphere as part of sea spray aerosol (SSA) and can influence fog and cloud microphysics as cloud condensation nuclei (CCN) or ice-nucleating particles (INP). Particularly in the remote Arctic region, significant knowledge gaps persist about the sources, the sea-to-air transfer mechanisms, atmospheric concentrations, and processing of this substantial organic group. In this ship-based field study conducted from May to July 2017 in the Fram Strait, Barents Sea, and central Arctic Ocean, we investigated the sea-to-air transfer of marine combined carbohydrates (CCHO) from concerted measurements of the bulk seawater, the sea surface microlayer (SML), aerosol particles and fog. Our results reveal a wide range of CCHO concentrations in seawater (22–1070 µg L−1), with notable variations among different sea-ice-related sea surface compartments. Enrichment factors in the sea surface microlayer (SML) relative to bulk water exhibited variability in both dissolved (0.4–16) and particulate (0.4–49) phases, with the highest values in the marginal ice zone (MIZ) and aged melt ponds. In the atmosphere, CCHO was detected in super- and submicron aerosol particles (CCHOaer,super: 0.07–2.1 ng m−3; CCHOaer,sub: 0.26–4.4 ng m−3) and fog water (CCHOfog,liquid: 18–22 000 µg L−1; CCHOfog,atmos: 3–4300 ng m−3). Enrichment factors for sea–air transfer varied based on assumed oceanic emission sources. Furthermore, we observed rapid atmospheric aging of CCHO, indicating both biological/enzymatic processes and abiotic degradation. This study highlights the diverse marine emission sources in the Arctic Ocean and the atmospheric processes shaping the chemical composition of aerosol particles and fog.
Prediction of absolute unsaturated hydraulic conductivity – comparison of four different capillary bundle models
Authors: Peters Andre , Iden Sascha C. , Durner Wolfgang 
Published: December 2023

Abstract. To model water, solute, and energy transport in porous media, it is essential to have accurate information about the soil hydraulic properties (SHPs), i.e., the water retention curve (WRC) and the soil hydraulic conductivity curve (HCC). It is important to have reliable data to parameterize these models, but equally critical is the selection of appropriate SHP models. While various expressions for the WRC are frequently compared, the capillary conductivity model proposed by Mualem (1976a) is widely used but rarely compared to alternatives. The objective of this study was to compare four different capillary bundle models in terms of their ability to accurately predict the HCC without scaling the conductivity function by a measured conductivity value. The four capillary bundle models include two simple models proposed by Burdine (1953) and Alexander and Skaggs (1986), which assume a bundle of parallel capillaries with tortuous flow paths, and two more sophisticated models based on statistical cut-and-random-rejoin approaches, namely those proposed by Childs and Collis-George (1950) and the aforementioned model of Mualem (1976a). To examine how the choice of the WRC parameterization affects the adequacy of different capillary bundle models, we utilized four different capillary saturation models in combination with each of the conductivity prediction models, resulting in 16 SHP model schemes. All schemes were calibrated using 12 carefully selected data sets that provided water retention and hydraulic conductivity data over a wide saturation range. Subsequently, the calibrated models were tested and rated by their ability to predict the hydraulic conductivity of 23 independent data sets of soils with varying textures. The statistical cut-and-random-rejoin models, particularly the Mualem (1976a) model, outperformed the simpler capillary bundle models in terms of predictive accuracy. This was independent of the specific WRC model used. Our findings suggest that the widespread use of the Mualem model is justified.
ANALISIS SENSORI ES PUTER SUBTITUSI KULIT PISANG KEPOK DAN BIJI CHIA SEBAGAI PRODUK TINGGI SERAT DAN RENDAH LEMAK
Authors: Nathaniela Talitha Sahda , Ismawati Rita 
Published: December 2023

Obesity is a nutritional problem with a prevalence that continues to increase from year to year. One of the efforts to prevent obesity is through the implementation of balanced nutrition guidelines by consuming lots of fiber sources and limiting high-fat intake. The purpose of this study was to develop a product in the form of ice puter substituted with banana peel with the addition of chia seeds to be sensorially evaluated by looking at differences in the level of liking for color, aroma, texture, taste and overall and analyzing fiber and fat content in ice puter formulations with a ratio of banana peel and chia seeds (30%; 50%) and (20g; 10g). This research is an experimental study using a 2x2 factorial completely randomized design (CRD). Sensory test research subjects were 30 panelists. The analisys data were using the Kruskall Wallis Test followed by the Mann Whitney Test. The results of the study based on the results of statistical tests showed that there were significant differences in the parameters of color, aroma, texture, taste and overall (p<0.05). Substitution of kepok banana peel and the addition of chia seeds influenced the level of panelists' liking and affected the fiber and fat content of es puter. Obesitas merupakan masalah gizi dengan prevalensi yang terus mengalami peningkatan dari tahun ke tahun. Salah satu upaya untuk pencegahan obesitas adalah melalui penerapan pedoman gizi seimbang dengan banyak mengkonsumsi sumber serat serta membatasi asupan tinggi lemak. Tujuan dari penelitian ini adalah mengembangkan produk berupa es puter yang disubtitusikan kulit pisang dengan penambahan biji chia untuk dievaluasi secara sensori dengan melihat perbedaan tingkat kesukaan warna, aroma, tekstur, rasa dan keseluruhan serta menganalisis kadar serat dan lemak pada formulasi es puter dengan perbandingan kulit pisang dan biji chia (30%;50%) dan (20g;10g). Penelitian ini merupakan penelitian eksperimen dengan menggunakan Rancangan Acak Lengkap (RAL) faktorial 2x2. Subjek penelitian uji sensori sebanyak 30 orang panelis. Data dianalisis menggunakan Uji Kruskall Wallis dilanjutkan dengan Uji Mann Whitney. Hasil penelitian berdasarkan hasil uji statistik menunjukkan bahwa terdapat perbedaan yang signifikan pada parameter warna, aroma, tekstur, rasa dan keseluruhan (p< 0.05). Subtitusi kulit pisang kepok dan penambahan biji chia memberikan pengaruh pada tingkat kesukaan panelis serta mempengaruhi kandungan serat dan lemak pada es puter.
The effect of modern hepatotoxicants on the elimination of caffeine
Authors: Popova O. S. , Ponamarev V. S. , Kostrova A. V. , Agafonova L. A. 
Published: December 2023

Hepatotoxicants are a variety of chemical substances that can have organ-specific damaging effects, which may be the result of their direct effects on both hepatocytes and other structural units of the liver. The purpose of this study is to evaluate the effect of modern hepatotoxicants on caffeine elimination. The studies were carried out in the vivarium of the Department of Pharmacology and Toxicology of the Federal State Budgetary Educational Institution of Higher Education of St. Petersburg State University of Medicine. Industrial substances of different chemical groups have been used to induce hepatotoxic conditions: phthalic anhydride, ethylenediamine and chloroform. All of the above toxicants were given in dosages for the immediate (within 24 hours) induction of hepatotoxic conditions. One day after the completion of the simulation, the levels of caffeine in the blood serum of the experimental animals were determined in full accordance with the previous series of experiments, using a dosage of 100 mg/kg, since with this dosage regimen we identified the most stable pharmacokinetic profiles of caffeine. Mathematical and statistical processing of the obtained data was carried out using the STATISTICA 6.1 program. The arithmetic mean (M) and its mean error (m) were calculated; the significance of the difference (p) was not calculated using the Student's test due to the exploratory nature of the study and the lack of comparison groups. Based on the conducted research, we can conclude that each hepatotoxicant has individual characteristic characteristics, which allows us to recommend a caffeine test for different types of hepatotoxicity, incl. unexpressed. That is, in this way it is possible to diagnose hepatotoxic conditions even in a latent form, which can be used as a method for assessing the toxicity of a drug at the stage of preclinical development.
The effect of an enzyme additive in combination with zinc in an ultrafine form on the productive performance of broiler chickens
Authors: Nechitailo K. S. , Sizova E. A. , Ryazantseva K. V. , Kvan O. V. 
Published: December 2023

Poultry farming is one of the most important and promising branches of animal husbandry. Given the increasing rate of industrial poultry farming, for the stable development of the industry and improving competitiveness in world markets, more and more attention is paid to the search for safe alternative agents to increase productivity. The study examined the strategy of feeding substances of different nature as feed additives, in particular, enzyme complexes separately (group I (0,05%; endo-1,4-beta-xylanase - 4000 units/g, alpha-amylase - 400 units/g and subtilisin - 8000 units/g)) and in combination with ultradispersed zinc (group II (3 mg/kg; 164±31,2 nm)). It was found that in group I the digestibility ratios of crude protein were higher by 6.03 % (P≤0.05), crude fiber by 3.68 % (P≤0.05), nitrogen-free extractive substances by 2.39 % (P≤0.05) compared to control. At the same time, in group II, changes were recorded in crude protein and crude fiber - an increase of 6.51% (P≤0.01) and 7.59% (P≤0.05), respectively. At 42 days of age, the live weight of broiler chickens I was 10.1% higher than control (P≤0.05), and in group II by 11.32% (P≤0.01). At the same time, the cost of feed per 1 kg of growth was minimal in group II, 16.79% lower than the control values. Thus, the maximum productive effect was observed with the introduction of a complex enzyme supplement in combination with zinc in ultradispersed form.