bluuebunny/crossref_metadata_2025_split huggingface dataset:
Acute Pulmonary Embolism and Immunity in Animal Models
Authors: Imiela Anna M. , Mikołajczyk Tomasz P. , Guzik Tomasz J. , Pruszczyk Piotr 
Published: January 2024

Abstract
Venous thromboembolism, encompassing acute pulmonary embolism (APE) and deep vein thrombosis (DVT), is a potentially fatal disease with complex pathophysiology. Traditionally, the Virchow triad provided a framework for understanding the pathogenic contributors to thrombus formation, which include endothelial dysfunction, alterations in blood flow and blood hypercoagulability. In the last years, it has become apparent that immunity plays a central role in thrombosis, interacting with classical prothrombotic mechanisms, oxidative stress and vascular factors. Thrombosis amplifies inflammation, and exaggerated inflammatory processes can trigger thrombosis mainly due to the activation of leukocytes, platelets, and endothelial cells. APE-related endothelium injury is a major trigger for immune system activation. Endothelium is also a key component mediating inflammatory reaction and it is relevant to maintain vascular permeability. Exaggerated right ventricular wall stress and overload, with coexisting systemic hypotension and hypoxemia, result in myocardial injury and necrosis. Hypoxia, tissue factor activation and cytokine storm are engaged in the thrombo-inflammatory processes. Thrombus development is characterized by inflammatory state vascular wall caused mainly by an early extravasation of leukocytes and intense selectins and cytokines production. Nevertheless, immunity of DVT is well described, little is known about potential chemokine and cellular differences between thrombus that develops in the vein and thrombus that detaches and lodges in the pulmonary circulation being a cause of APE. There is a paucity of data considering inflammatory state in the pulmonary artery wall during an acute episode of pulmonary embolism. The main aim of this review is to summarize the knowledge of immunity in acute phase of pulmonary embolism in experimental models.
Determination of microbiological quality of boiled crayfish (Astacus leptodactylus) samples treated with chitosan
Authors: Ceylan Zafer , İnanlı Ayşe Gürel , Basahel Abdulrahman , Karaboga Dervis , TahsinYilmaz Mustafa 
Published: January 2024

Abstract
Coating crayfish (Astacus leptodactylus) meat samples with chitosan solution could be an effective approach to limit microbiological spoilage. During the 18-day cold storage period at 2°C±1, mesophilic aerobic bacteria (MABc), psychrophilic bacteria (PBc), yeast mold count (YMc), anaerobic bacteria (AnBc), and Enterobacteriaceae growth in the samples coated with chitosan (0.5% and 1%) and also control group samples were tested. Crayfish samples coated with chitosan (0.5% and 1%) had a lower TMABc (6.58 to 4.60 log CFU/g: up to 30.09%), TPBc (3.77 to 1.99 log CFU/g: up to 47.21%), TYMc (1.84 to 1.27 log CFU/g: up to 30.97%), TAnBc (3.69 to 1.88 log CFU/g: up to 49.05%), and Enterobacteriaceae (3.49 to 2.60 log CFU/g: up to 25.50%) counts as compared with control group samples at 2°C±1. The results particularly based on mesophilic anaerobic bacteria suggested that the application would be a promising approach to limit microbial growth and provide food safety for boiled crayfish meat samples.
Ameliorating effects of dietary parsley (Petroselinum crispum) on ammonia toxicity in the rainbow trout, Oncorhynchus mykiss: growth, digestive enzymes, immunity, and stress resistance
Authors: Hajirezaee Saeed , Sharifi Sara , Momeninejad Ali , Ahani Saman , Anzabi Mojtaba Pourahad , Taheri Somayeh 
Published: January 2024

Abstract
Use of phytobiotics as immunostimulant is increasing in aquaculture. In this study, the immune and growth promoting effects of parsley extract (PUE) were examined in the rainbow trout. In this regard, the various dietary levels of parsley extract (PUE), Petroselinum crispum (0, 0.5, 1.5, 3, and 4.5%) was added to the diet of rainbow trout to assay its potentials on immunity, growth, digestive enzymes, and mitigating ammonia-induced stress. A total of 450 fish (15.43±0.06 g; mean ± SE) were distributed into fifteen 300-L fiberglass tanks (30 fish per tank) and fed PUE for 60 days and then challenged with unionized ammonia (0.3 mg/l). According to results, PUE mainly at 3−4.5% levels increased the growth, lipase and protease activities, humoral and mucosal immune components and liver antioxidant enzymes activities. These effects were kept even after ammonia stress, where the immune components were higher in PUE-treated fish than the control group. Furthermore, the dietary PUE reduced ammonia-related oxidative stress, as malondialdehyde (MDA) values (as the indicator of lipid peroxidation) decreased in fish fed PUE. The concentrations of liver metabolic enzymes in blood, both before and after ammonia stress declined in the fish fed PUE. Our findings demonstrated the growth and immune boosting and ammonia-stress mitigating properties of PUE in rainbow trout.
The effect of extra-oral traction : a review
Authors: Howell Susan 
Published: January 2024

Abstract
The application of force to bone has been shown to produce a change in its shape or morphology. This paper reviews the literature relating to the principles of such force application by extra-oral appliances to the maxilla and mandible both in animals and humans. The significance of direction of force, amount of force, and timing of force application is stressed. Studies of craniofacial changes associated with the use of face-bows and cervical straps in orthodontic treatment are closely examined. The post-treatment changes, after the extra-oral forces have been discontinued, are also discussed.
Applications of photogrammetry to orthodontics
Authors: Thomann John Von , Rivett Leo J. 
Published: January 2024

Abstract
An investigation was conducted into the potential of utilizing standardized photogrammetry techniques to evaluate facial soft tissue morphology. A head holding device was used to provide a standardized reference system and the accuracy of repositioning for a second photographic recording was evaluated. Three dimensional co-ordinates of points on the facial surface were derived by analytical photogrammetry procedures from stereo photographs acquired via a pair of stereometrie cameras. These points were manipulated via computer programs to provide frontal and horizontal face contour plots. Quantitative volume measurements determined from the skin surface to a constructed datum plane provided assessment of facial asymmetry across a constructed reproducible frontal midline, the perpendicular bisector of the interpupillary line. Photogrammetry was found to be a versatile, non-contact and precise three-dimensional recording method, with potential application to basie research and to the clinical management of orthodontic and oral surgery patients.
Functional appliances: Which one, When? Part 1 — Rationale for selection
Authors: Roberts Graeme L. 
Published: January 2024

Abstract
One current question is whether functional appliance therapy is capable of producing clinically significant changes in the human dento-facial complex under realistic treatment conditions. Another question is whether the different designs of functional appliances have differing modes of action, and, if so, how does the clinician select the one most appropriate for the requirements of the case in hand, and when?
Current knowledge of the responses elicited by functional appliances is reviewed.
Descriptions of the “ideal” patient for each appliance is given, along with indications and contraindications. Specific associations are emphasized, such as vertical control and Teuschers, decrowding and Fränkels, Herbst and breakage prevention, retention and Bionators. Case reports are also presented to help the selection process.
Experiences with Unerupted Anterior and Posterior Teeth
Authors: Goh Gek Kiow , Kaan Sheung K. 
Published: January 2024

Abstract
The causes of tooth impaction are as numerous as are ways to manage the problem. Treatment is usually instituted only after an unfavourable eruption prognosis of the impacted tooth has been established from radiographic and clinical examination. Advantages of guided eruption and surgical removal have to be weighed. Fifteen cases of various degrees of impaction, difficulty of treatment, complications and failures of eruption are discussed.
The Rocky Mountain-Samuel Bulkley Travelling Fellowship
Authors: Collett Anthony 
Published: January 2024

Abstract
Rocky Mountain Orthodontics and The Australian Society of Orthodontists Foundation for Research and Education provide a Fellowship to enable a new orthodontic graduate the opportunity to spend time overseas engaged in research. The present discussion deals not so much with the details of the research (which are to be published ), but rather provides an overview of the Fellowship activities, and aims to encourage present postgraduate students to apply for the award.
Orchestrating Distributed Computing and Web Technology with Semantic Web and Big Data
Authors: Amanoul Sandy Victor , Abdulrahman Lozan M. , Abdullah Rozin Majeed , Qashi Riyadh 
Published: January 2024

AbstractComplex data systems are incapable of processing large data volumes, rendering the task of retrieving pertinent information unattainable. The advent of the Internet has amplified the significance of accessible and readily available information. Additionally, it receives support from the World Wide Web Consortium (W3C) and global organizations responsible for establishing web standards, such as Web Ontology, Inc. It expands the functionality of the website to facilitate the retrieval, integration, and transmission of information. In recent years, several major organizations have shown a strong inclination towards using semantic technologies for the purpose of collecting Big Data. Undoubtedly, there are other advantages of integrating this into the Creative. It enhances the ability of end-users to manage data from many repositories, focuses on changing the corporate environment and the user experience, and incorporates individual definitions and integrates several data sources. Furthermore, the market’s evolving expectations and contemporary organizational practices require an adaptable but all-encompassing information strategy. Integration of data warehousing may be achieved by the use of scattered corporate ontologies. This study explores the impact of the Semantic Web on enhancing the intelligence of Big Data. It analyses the obstacles and opportunities associated with the integration of Big Data with the Semantic Web.
PENGARUH PEMBERIAN ASI EKSKLUSIF TERHADAP KEJADIAN DIARE PADA ANAK USIA 1-3 TAHUN
Authors: Wardani Ni Made Elsa , Witarini Komang  Ayu , Putra Putu Junara , Artana I Wayan Dharma 
Published: January 2024

Abstrak
Diare adalah suatu penyakit yang ditandai dengan adanya perubahan bentuk dan konsistensi tinja yang lembek sampai mencair dan bertambahnya frekuensi buang air besar yaitu 3 kali atau lebih dalam sehari yang dapat disertai dengan muntah atau tinja yang berdarah. Kejadian diare pada anak dapat terjadi akibat pemberian susu formula sebagai pengganti ASI. Penelitian ini bertujuan untuk dapat mengetahui pengaruh pemberian ASI Eksklusif terhadap kejadian diare pada anak usia 1-3 tahun. Penelitian ini dilakukan dengan metode analitik menggunakan studi kasus kontrol dengan sampel yang sesuai dari populasi berdasarkan kriteria inklusi dan eksklusi. Data dianalisis menggunakan software SPSS versi 26 untuk mendapatkan pengaruh pemberian ASI Eksklusif terhadap kejadian diare pada anak usia 1-3 tahun dan dengan memperhatikan faktor lain seperti keberadaan toilet, berat bayi saat lahir, tingkat pendidikan ibu, sumber air minum, kebersihan diri, kebersihan lingkungan dan status gizi. Hasil menunjukkan tidak terdapat hubungan yang signifikan antara pemberian ASI Eksklusif terhadap kejadian diare pada anak usia 1-3 tahun. Saran yang diberikan yaitu melakukan penelitian kembali dalam rentang waktu yang singkat sehingga memudahkan dalam mengingat kembali hal-hal yang telah dialami saat wawancara. Selain itu juga perlu memperhatikan berbagai faktor lain seperti kebersihan lingkungan, kebersihan diri, dan juga kebersihan peralatan makan dan botol susu sebelum digunakan.
Kata Kunci: Diare, ASI Eksklusif, pengaruh
HUBUNGAN FAKTOR LINGKUNGAN DAN PERILAKU MASYARAKAT DENGAN RIWAYAT KEJADIAN DEMAM BERDARAH DENGUE (DBD) DI LINGKUNGAN CANDI BARU GIANYAR
Authors: Divya Nirmala Putu Ayu , Swastika I Kadek , Sudarmaja I Made , Ariwati Ni Luh , Ariwati Ni Luh 
Published: January 2024

Demam berdarah dengue merupakan salah satu penyakit yang disebabkan oleh infeksi virus dengue. Bali merupakan salah satu daerah endemis dengue, dimana Gianyar merupakan kabupaten dengan tingkat kasus yang tinggi. Faktor-faktor yang dapat memicu demam berdarah dengue adalah faktor lingkungan dan perilaku masyarakat. Sehingga penelitian mengenai faktor lingkungan dan perilaku masyarakat terhadap kejadian demam berdarah dengue perlu dilakukan. Penelitian ini merupakan penelitian analitik observasional dengan metode pendekatan cross-sectional dengan mengambil data primer pada Juli – Agustus 2019 dari kepala keluarga yang berdomisili di Lingkungan Candi Baru Gianyar. Teknik pengumpulan sampel adalah minimum sampling dengan hasil 94 kepala keluarga atau yang mewakili sebagai responden. Analisis data dilakukan secara bertahap dengan analisis univariat dan bivariat. Hasil uji chi-square menunjukkan hubungan tidak bermakna antara faktor lingkungan yaitu kepadatan rumah (p value = 0,296, OR = 4,941, CI = 0,494 – 49, 429) serta kondisi tempat penampungan air (p value = 1,000, OR = 0,918, CI = 0,206 – 4,093) dan perilaku masyarakat yaitu pengetahuan responden (p value = 0,508, OR = 1,625, CI = 0,436 – 6,056), sikap responden (p value = 0,289, OR = 1,624, CI = 0,701 – 3,761) serta dan tindakan responden (p value = 0,353, OR = 0,471, CI = 0,119 – 1,868) dengan riwayat kejadian demam berdarah dengue.
Kata kunci : demam berdarah dengue, faktor lingkungan, perilaku masyarakat
KARAKTERISTIK PASIEN KISTA OVARIUM DI RSUP SANGLAH DENPASAR PERIODE JANUARI 2019 - DESEMBER 2019
Authors: Dewi Putu Itta Sandi Lesmana 
Published: January 2024

ABSTRACT
Ovarian cyst is gynecological tumors that are often found in women of childbearing age. The formation of ovarian cyst is influenced by the risk factors such as reproductive age, family history, nulliparous, and hormonal therapy. The purpose of this study is to determine the characteristics of ovarian cyst patients being treated in Sanglah General Hospital. The research design of this study is cross sectional design with retrospective descriptive research. Data were taken by using a total sampling method from the medical records of ovarian cyst patients during the period of January 2019 – December 2019. The research subjects were patients who had been diagnosed with ovarian cyst and recorded in the medical record of Sanglah General Hospital. The patients’ characteristics were described based on age, parity, menstrual status, cyst classification, cyst location, and medical management. The finding of this study is that out of the total sample of 67 medical records of the ovarian cyst patients, there were patients with the majority categories of age at 36-50 years old (37,3%), being dominated by women who had menstruation (67,2%), and mainly found in multiparous women (41,8%). The ovarian cyst was mostly found with benign type (52,2%), which was more common in the right ovary (49,3%). The medical management that was given in Sanglah General Hospital was mostly in the form of operative measures (74,6%). From this study, it can be concluded that ovarian cysts are most often found in women at childbearing age who have experienced menstruation. Ovarian cysts are more common in multiparous women with predominantly benign ovarian cyst type. Ovarian cysts are more common in the right ovary and predominantly performed by surgery.
Keywords: Ovarian cyst, characteristics, Sanglah General Hospital
Gambaran Tingkat Kecemasan Pasien Pre Operasi Pembedahan Ortopedi di Rumah Sakit Umum Pusat Sanglah
Authors: Sitinjak Melisa Patricia , Dewi Dewa Ayu Mas Shintya , Sidemen I Gusti Putu Sukrana 
Published: January 2024

ABSTRAK
Tindakan pembedahan dapat menimbulkan kecemasan bagi pasien, khususnya pada periode pre operasi. Kecemasan yang dirasakan dapat berhubungan dengan prosedur pembedahan maupun anestesi yang akan dilakukan. Beberapa penelitian menemukan bahwa jenis kelamin, tingkat pendidikan, dan pengalaman operasi dapat memberikan pengaruh terhadap tingkat kecemasan pasien. Penelitian ini bertujuan untuk mengetahui gambaran tingkat kecemasan pasien pre operasi pembedahan ortopedi. Penelitian ini merupakan penelitian deskriptif cross-sectional dan menggunakan data primer dari hasil kuesioner Hamilton Anxiety Rating Scale sebagai alat ukur tingkat kecemasan pasien. Data dikumpulkan pada periode Oktober hingga November 2020 di Rumah Sakit Umum Pusat Sanglah. Subjek penelitian didapatkan sebanyak 26 pasien. Hasil penelitian terdapat 88.5% pasien tidak merasakan kecemasan. Baik berdasarkan jenis kelamin, pengalaman operasi, dan tingkat pendidikannya, tidak menunjukkan adanya perbedaan terhadap tingkat kecemasan pasien pada penelitian ini.
Kata kunci: Kecemasan, pre operasi, pembedahan ortopedi
Gambaran Karakteristik Kanker Payudara Metastasis Berdasarkan Subtipe Molekuler di RSUP Sanglah Tahun 2014- 2019
Authors: Bernadette Natasha Lumongga , Setiawan I Gede Budhi , Suryawisesa IB Made Made , Wetan Ni G.A.A. Manik Yuniawaty 
Published: January 2024

ABSTRAK
Angka kejadian kanker payudara meningkat setiap tahunnya. Subtipe molekuler merupakan prediktor yang baik dalam memprediksi kejadian metastasis. Studi Epidemiologi ini dilakukan untuk mempelajari karakteristik pasien kasus kanker payudara di Indonesia, khususnya di Rumah Sakit Umum Pusat Sanglah, Denpasar selama periode 2014-2019. Penelitian ini merupakan penelitian deskriptif observasional dengan pendekatan potong lintang. Penelitian ini menggunakan data sekunder Cancer Registry Perhimpunan Ahli Bedah Onkologi Indonesia (PERABOI), Divisi Bedah Onkologi RSUP Sanglah. Metode pengambilan sampel adalah total sampling. Dari 161 sampel kasus kanker payudara metastasis diperoleh hasil kejadian metastasis kanker payudara paling banyak mengalami metastasis ke paru-paru yaitu sebanyak 108 kasus (48,9%). Kejadian metastasis kanker payudara paling banyak dialami oleh pasien dengan subtipe molekuler Luminal B-positif yaitu sebanyak 45 kasus (28%). Pasien dengan metastasis tulang cenderung memiliki subtipe molekuler Luminal B-positif yaitu sebanyak 19 (32,2%). Pasien dengan metastasis paru-paru cenderung memiliki subtipe molekuler HER2+ yaitu sebanyak 28 (14,2%). Pasien dengan metastasis otak cenderung memiliki subtipe molekuler HER2+ yaitu sebanyak 6 (50%). Pasien dengan metastasis liver, cenderung memiliki subtipe molekuler HER2+ dan Luminal B-positif yaitu sebanyak 11 kasus (26,2%). Hasil penelitian ini dapat digunakan sebagai dasar penelitian lebih lanjut untuk mempelajari kejadian kanker payudara metastasis.
Kata kunci : Kanker Payudara Metasasis, Organ Metasastasis, Subtipe Molekuler
PERBEDAAN POLA LUKA PADA KORBAN KECELAKAAN LALU LINTAS ANTARA DEATH ON ARRIVAL (DOA) DAN YANG DIRAWAT MENINGGAL DI RSUP SANGLAH TAHUN 2015
Authors: Ardhenariswari Ni Putu , Putu Alit Ida Bagus 
Published: January 2024

Kecelakaan lalu lintas merupakan masalah kesehatan yang cukup serius karena dapat mengakibatkan kerugian material, kecacatan, bahkan kematian. Pola luka merupakan gabungan dari beberapa luka. Penelitian ini bertujuan untuk mengetahui perbedaan pola luka pada korban kecelakaan lalu lintas antara death on arrival (DOA) dan yang dirawat meninggal di RSUP Sanglah tahun 2015. Penelitian ini menggunakan jenis penelitian analitik dengan rancangan penelitian cross-sectional. Data-data didapatkan dari data sekunder yaitu laporan visum et repertum (VeR). Jumlah total sampel penelitian yaitu 84 sampel (42 sampel DOA dan 42 sampel rawat meninggal). Analisis data dengan analisis univariat dan bivariat dengan menggunakan uji chi-square dan manual untuk jenis luka. Hasil menunjukkan regio luka tungkai atas pada DOA (55,4%) dan rawat meninggal (44,6%) berbeda signifikan secara statistik (P<0,05) tetapi tidak berbeda signifikan secara klinis. Jenis luka terbuka terbanyak yaitu kepala leher pada DOA (73,8%), rawat meninggal (30,9%). Jenis luka memar terbanyak DOA yaitu tungkai atas (47,6%), rawat meninggal yaitu kepala leher (57,1%). Jenis luka lecet terbanyak korban DOA yaitu tungkai atas (83,3%), rawat meninggal yaitu tungkai bawah (78,6%). Fraktur basis cranii pada DOA (65,5%) rawat meninggal (34,5%), patah tulang wajah pada DOA (85,2%) rawat meninggal (14,8%), patah tulang dada pada DOA (88,9%) rawat meninggal (11,1%), berbeda signifikan (P<0,05). Dapat disimpulkan bahwa terdapat perbedaan pola luka pada korban kecelakaan lalu lintas antara DOA dan yang dirawat meninggal di RSUP Sanglah tahun 2015.
Kata Kunci: Pola luka kecelakaan lalu lintas, DOA, rawat meninggal
PENGARUH PEMBERIAN SEDUHAN KOPI TERHADAP KADAR TRIGLISERIDA DAN KOLESTEROL TOTAL PADA MENCIT (Mus musculus L.) YANG DIBERI PAKAN TINGGI LEMAK
Authors: Noegroho Benediktus Brilian Chrisma , Dewi Wiryanthini Ida Ayu , Surudarma I Wayan , Kusmawati Amy Yelly 
Published: January 2024

ABSTRAK
Hiperlipidemia merupakan kelainan metabolisme lipid. Fraksi lipid yang mengalami kenaikan adalah kolesterol total, trigliserida, LDL, serta penurunan HDL. Senyawa aktif berupa asam klorogenat, serta polifenol, dan flavonoid dalam kopi Arabika Kintamani dapat menghambat penyimpanan karbohidrat dan lipid. Penelitian ini merupakan penelitian eksperimental menggunakan metode True Experimental Post Test Only Control Group Design. Tiga puluh ekor mencit dibagi menjadi lima kelompok, yaitu kelompok control (diet standar), hiperlipid (diet tinggi lemak), dan kopi (diet tinggi lemak dan seduhan kopi 0,3ml/hari, 0,6ml/hari, 1ml/hari). Diet tinggi lemak yang diberikan terdiri dari minyak babi dan kuning telur bebek. Data dianalisis menggunakan SPSS. Kopi berpengaruh terhadap kadar kolesterol total mencit, didapatkan nilai P 0,02 (p<0,05). Kopi berpengaruh terhadap kadar kolesterol total, namun tidak berpengaruh terhadap kadar trigliserida mencit yang diberi pakan tinggi lemak.
Kata Kunci: Hiperlipidemia, Kolesterol total, Trigliserida, Seduhan Kopi