bluuebunny/crossref_metadata_2025_split huggingface dataset:
DNA methylation in poultry: a review
Authors: Ju Xing , Wang Zhijun , Cai Danfeng , Bello Semiu Folaniyi , Nie Qinghua 
Published: November 2023

AbstractAs an important epigenetic modification, DNA methylation is involved in many biological processes such as animal cell differentiation, embryonic development, genomic imprinting and sex chromosome inactivation. As DNA methylation sequencing becomes more sophisticated, it becomes possible to use it to solve more zoological problems. This paper reviews the characteristics of DNA methylation, with emphasis on the research and application of DNA methylation in poultry.
Experience with carnitine palmitoyltransferase II deficiency: diagnostic challenges in the myopathic form
Authors: Yazıcı Havva , Ak Gunes , Çelik Merve Yoldas , Erdem Fehime , Yanbolu Ayse Yuksel , Er Esra , Bozacı Ayse Ergül , Güvenç Merve Saka , Aykut Ayca , Durmaz Asude , Canda Ebru , Uçar Sema Kalkan , Çoker Mahmut 
Published: November 2023

Abstract

Objectives
Carnitine palmitoyltransferase II (CPT II) deficiency is an autosomal recessive disorder of long-chain fatty acid oxidation. Three clinical phenotypes, lethal neonatal form, severe infantile hepatocardiomuscular form, and myopathic form, have been described in CPT II deficiency. The myopathic form is usually mild and can manifest from infancy to adulthood, characterised by recurrent rhabdomyolysis episodes. The study aimed to investigate the clinical features, biochemical, histopathological, and genetic findings of 13 patients diagnosed with the myopathic form of CPT II deficiency at Ege University Hospital.

Methods
A retrospective study was conducted with 13 patients with the myopathic form of CPT II deficiency. Our study considered demographic data, triggers of recurrent rhabdomyolysis attacks, biochemical metabolic screening, and molecular analysis.

Results
Ten patients were examined for rhabdomyolysis of unknown causes. Two patients were diagnosed during family screening, and one was diagnosed during investigations due to increased liver function tests. Acylcarnitine profiles were normal in five patients during rhabdomyolysis. Genetic studies have identified a c.338C>T (p.Ser113Leu) variant homozygous in 10 patients. One patient showed a novel frameshift variant compound heterozygous with c.338C>T (p.Ser113Leu).

Conclusions
Plasma acylcarnitine analysis should be preferred as it is superior to DBS acylcarnitine analysis in diagnosing CPT II deficiency. Even if plasma acylcarnitine analysis is impossible, CPT2 gene analysis should be performed. Our study emphasizes that CPT II deficiency should be considered in the differential diagnosis of recurrent rhabdomyolysis, even if typical acylcarnitine elevation does not accompany it.
PLANNING SEAWEED FARMING BASED ECOTOURISM: A TOURISM SPECTRUM APPROACH IN BANTAENG REGENCY, INDONESIA
Authors: Junaid Ilham , Mior Shariffuddin Nur Shahirah , Al Qassem Amer 
Published: November 2023

Ecotourism allows tourism policymakers and the community to manage nature-based tourism. However, although ecotourism is a promising idea or concept, this opportunity is only partially a reality. It requires a particular study relative to the current conditions of the destination and other aspects that can support the implementation of ecotourism. The objectives of this study are to 1) examine the opportunities for implementing ecotourism in a coastal area, Bantaeng regency of Indonesia; 2) analyse the environmental impacts resulting from seaweed-farming activities and their relation to tourism. This research, conducted in June 2020, applies a qualitative method. Data-collection methods included interviews with seaweed farmers, field notes (observation) and a review of published information online. This study utilises the tourism opportunity spectrum (TOS) in analysing the current conditions in the research location. The results showed that floods caused crop failure, prompting the need for alternative income for the community to survive. Ecotourism can represent an opportunity for seaweed-farming communities if on-site management factors and goals are applied with the principle of sustainability. This study found that TOS helps understand the impact resulting from the activities of the seaweed-farming community in Bantaeng regency—the use of massive numbers of plastic bottles as floats conflicts with the principle of ecotourism. The TOS approach views ecotourism planners, including the government and the tourism industry, as being able to open educational opportunities for the community and visitors.
ASSESSING THE SOCIAL VALUES OF HISTORICAL WATERFRONT: A CASE STUDY OF SUNGAI PETANI, KEDAH, MALAYSIA
Authors: Ying Lim Jeng , Hassan Linda Shafarina , Zainal Abidin Nurdiyana , Hashim Lim Noor Hashimah , Hasnan Liyana 
Published: November 2023

Waterfronts are vibrant areas that are heavily utilised by people with activities in pre-industrial cities. Riverfronts and towns have a tight association during this time frame. As a result, industrial plants were shut down and modes of transportation were altered. In the face of rapid urbanisation and industrialisation in Sungai Petani, Kedah, there is a growing concern that the economic and environmental changes may negatively affect the social values among the community. Overall, this research aims to identify several key areas for the historical waterfront regeneration of Sungai Petani. A social impact assessment was conducted to analyse the social values of the existing waterfront to expand the aspects of social and culture to the planning of urban waterfront regeneration in Sungai Petani. Results of the questionnaire revealed that respondents showed their satisfaction and opinion upon the waterfront element. There are 61.6% proportion of the respondents who consider that the community cohesiveness is the greatest strength of the Sungai Petani’s waterfront. This is followed by cultural vibrancy (47.2%), beautiful streets (40.8%), streets in harmony with nature (28.8%), and beautiful river (12%). At the end of the study, solutions were suggested for the regeneration of historical waterfront and correcting mistakes in existing spaces in light of these determinations.
Features of pyelonephritis course in adolescent females with co-existing anаemic syndrome
Authors: Lembryk I.S. , Shlimkevych I.V. , Stefanyshyn A.B. , Zhyliak O.V. , Kostyrko N.I. 
Published: November 2023

Background. Anaemic syndrome of complex origin is not uncommon in urinary tract infection, particularly in dietary non-adherence, menstrual cycle disorders, or concomitant digestive diseases, recurrent respiratory infections, etc. However, there is currently insufficient epidemiological data on this comorbidity in the literature. This study aims to establish the features of pyelonephritis course in its combination with anaemic syndrome in children. Materials and methods. We analysed the medical records of 200 children aged 0 to 17 years with acute non-complicated pyelonephritis, complicated and recurrent urinary tract infections for 2012–2017. In the second stage of our work, we comprehensively examined 85 girls aged 11 to 17 who underwent inpatient treatment between 2018 and March 2023. Thirty children of the same age and gender made up the comparison group. A paediatric gastroenterologist, a paediatric gynaecologist and/or urologist examined all patients. Immunochemical method with electrochemiluminescence immunoassay was used to assess ferritin content; also, serum iron and total iron-binding capacity were measured. Results. Anaemic syndrome is common in most girls with urinary tract infections (58.8 % of сases). Among the causes, the follo­wing are distinguished: menstrual cycle disorders with abnormal uterine bleeding (50.0 %), chronic digestive disorders, in particular malabsorption syndrome of unknown origin (25.0 %), recurrent bronchopulmonary disorders (15.0 %), and unbalanced diet (10.0 %). The features of urinary tract infections and concomitant iron deficiency in children include fatigue (55.0 % in acute non-complicated pyelonephritis vs. 40.0 % in complicated urinary tract infections, р < 0.05), dizziness (35.0 % in acute non-complica­ted pyelonephritis vs. 15.0 % in recurrent urinary tract infections, χ2 = 48.6532, р < 0.05), and pallor (25.0 % in complicated urinary tract infections vs. 10 % in recurrent urinary tract infections, χ2 = 0.7168, р > 0.05). The ferritin level was the highest in patients with complicated urinary tract infections (18.2 µg/mL). In patients with recurrent urinary tract infections, this indicator was the lo­west — 5.0 µg/mL. Conclusions. Retrospective analysis of medical records confirmed the presence of anaemia in 30.0 % of girls with inflammatory kidney diseases. During the physical examination, 58.8 % of female adolescents with urinary tract infections had signs of anaemic syndrome.
Changes of immunological biomarkers in pediatric patients with seasonal allergic rhinitis
Authors: Shcherbak V.V. , Kryuchko T.O. , Bubyr L.M. , Izmailova O.V. , Poda O.A. 
Published: November 2023

Background. Seasonal allergic rhinitis shows a constant upward trend not only among the adults but also in the children’s population. A significant percentage of patients have a moderate and severe course of the disease, which leads to a significant deterioration in their quality of life. Since the pathogenesis of allergic rhinitis is represented by a complex cascade of immunological reactions involving a number of cytokines that play a role in the development of allergic inflammation of the upper respiratory tract, the priority direction of our work was an in-depth study of the pathogenetic mechanisms of this disease. The purpose was to investigate the levels of interleukin-33 (IL-33) and its suppression of tumorigenicity 2 (ST2) receptor in the blood serum of children with hay fever, depending on the age and severity of the disease, followed by the determination of correlations of these indicators with various clinical and immunological parameters of seasonal allergic rhinitis. Materials and methods. Forty-two patients aged 6–17 years with seasonal allergic rhinitis and 26 healthy children (controls) took part in the study. Severity of nasal and extra-nasal symptoms of allergic rhinitis was determined using a visual analog scale. Skin prick testing was performed according to generally accepted standards during remission using a standard pollen panel. Quantitative measurement of serum indicators of interleukin-33 and ST2 was carried out by the method of solid-phase enzyme immunoassay. A mandatory condition for conducting the study was the presence of written informed consent from the parents. Results. The study of serum levels of IL-33 and ST2 showed statistically higher concentrations in the group of children with a severe course of seasonal allergic rhinitis, a direct correlation of medium strength between content of the above cytokines in children with a mild SAR (τ = 0.65; p < 0.05) and a strong dependence in patients with moderate (τ = 0.76; p < 0.01) and severe (τ = 0.80; p < 0.05) course. When comparing the mean values of IL-33 and ST2, no significant changes were found depending on age and the presence of mono- or polysensitisation among patients with allergic rhinitis. In children with seasonal allergic rhinitis and concomitant bronchial asthma, there was a statistically significant tendency towards a more severe course of the disease with correspondingly higher values of IL-33 and ST2 compared to patients with isolated seasonal allergic rhinitis. Conclusions. The obtained results of the immunological study made it possible to emphasize the diagnostic significance of IL-33 and its receptor ST2 as potential biomarkers in the development of allergic inflammation in pediatric patients with seasonal manifestations of rhinitis.
«Home is there, far away, there»: songs by P. Haas from the concentration camp Theresienstadt
Authors: Федусова А.А. 
Published: November 2023

В статье освещается сочинение чешского композитора Павла Хааса, ставшее ярким воплощением темы дома и бездомья в музыке, — Четыре песни на слова китайских поэтов. Три лейтмотива, основанные на мелодии хорала «Святой Вацлав», главного символа дома, не соединяются здесь в единое целое, подсказывая, что дом в общей концепции произведения остается недостижимой мечтой. Автор статьи предпринимает попытку по-новому взглянуть на финал цикла, который в зарубежном музыковедении традиционно понимается как «возвращение домой».
The article focuses on a work by the Czech composer Pavel Haas, which has become a vivid embodiment of the theme of home and homelessness in music, that is Four Songs to the Words of Chinese Poets. The three leitmotifs based on the melody of the St. Wenceslas Chorale, the main symbol of home, do not unite here, suggesting that home in the overall concept of the work remains an unattainable dream. The author of the article attempts to take a new look at the finale of the cycle, which in foreign musicology is traditionally understood as “the return home”.
Tratamiento de superficie en restauraciones de zirconia para hacer más confiable su adhesion. Reporte de dos casos clínicos: seguimiento a corto plazo
Authors: Fernández Franco Diego Andrés , Velastegui Atahualpa David Alfonso , Díaz Segovia María Cristina , Cascante Calderón Marcelo 
Published: November 2023

Este informe de 2 casos describe la mejor manera de establecer una unión química entre la zirconia (3 Y-TZP) y un cemento resinoso. Los investigadores han descubierto que un tratamiento superficial ideal de esta cerámica, considerada químicamente inerte, debería realizarse mediante un arenado triboquímico, seguido de silano y un agente adhesivo a base de 10 MDP. Materiales y Métodos: Dos puentes de 3 Y-TZP fueron preparados en pacientes que, no querían someterse a un tratamiento convencional. Lo puentes se cementaron, siguiendo el protocolo recomendado. Se hizo un seguimiento de dos años y medio para ver su evolución. Resultados: La combinación del arenado triboquímico más los primers cerámicos, lograron proporcionar una adhesión confiable a esta cerámica cristalina. No se observaron despegamientos, ni ningún tipo de sensibilidad postoperatoria. Los pacientes no experimentaron ninguna dificultad en ninguna de sus funciones orales durante todo este tiempo. Conclusiones: Se comprobó que es posible adherir químicamente y de forma confiable la 3 Y-TZP, incluso en casos extremos en los que es imposible optar por realizar tratamientos tradicionales de prótesis fija.
Programa de educación para la salud bucal en adultos mayores
Authors: García Vázquez Paola Elena , Borges Yáñez Socorro Aída , Sánchez García Sergio 
Published: November 2023

Introducción: Existen diversas estrategias de promoción de la salud bucal en adultos mayores que no han mostrado ser eficaces. Objetivo: Evaluar el impacto de una obra de teatro con enfoque de promoción de la salud, sobre los conocimientos de salud bucal en adultos mayores. Materiales y Métodos: Intervención comunitaria de promoción de la salud utilizando el teatro como estrategia con un diseño antes y después. 100 adultos ≥60 años residentes de dos Centros Gerontológicos en la Ciudad de México y una Casa de Día para el Adulto Mayor en el Estado de México. La obra de teatro “Más vale prevenir que lamentar” presenta aspectos de higiene bucal, causas de halitosis y caries. Evaluación basal e inmediatamente después de la intervención en la Casa de Día. En los Centros gerontológicos evaluación basal y siete días después. Análisis descriptivo y prueba no paramétrica pareada. Resultados: 100 adultos mayores. Media de edad de 75.5 ± 9.2 años, 81% mujeres. En la Casa de Día y en los Centros Gerontológicos se observó un incremento positivo en los conocimientos sobre uso de hilo dental (61.9% a 88.1%, p<0.001; 55.1% a 81.0%, p<0.001 respectivamente),tipo de cepillo dental (38.1% a 59.5%, p=0.012; 37.9% a 55.1%, p<0.001 respectivamente), tiempo adecuado para el cambio de cepillo (54.7% a 76.1%, p=0.012; 44.8% a 67.2%, p=0.002, respectivamente) y “ubicación de la caries” (26.1% a 42.8%, p=0.008; 25.8% a 44.8%, p=0.016 respectivamente). Conclusión: Se observaron cambios positivos a corto plazo en los conocimientos de salud bucal. Se recomienda promover esta modalidad educativa en la población adulta.
REVOCATION OF VAT EXEMPTION FOR ELECTRICITY AND WATER AND ITS IMPACT ANALYSIS
Authors: Trisandi Dicky , Nasrudin Rus’an 
Published: November 2023

Covid-19 pandemic has brought an impact on global economy which turn down the ranked of Indonesia from a country with upper middle income to lower middle income. In response to this matter, the Indonesian government has been issued several policies to increase the acceleration in economic and support economic recovery in order to optimize the state revenues which can be done by revoking of VAT exemptions on electricity and water. This research aims to explore further regarding the effect of poverty and inequality which arise from this revoking policy. The analysis conducted by microsimulation model method to measure poverty and inequality based on individual/household gains or losses caused by taxes policy. Main data obtained from national socio-economic survey data which submitted by BPS. Broadly speaking, these simulation results are indicates that this policy had slightly increases poverty rate, but did not affect on inequality. Through this research it was found an alternative way to compensate with assumption that this costs are source of additional revenue obtained from this imposition of normal VAT rates on electricity and water for households, so its distribution through cash transfers could be an effective way to fixes the poverty levels and inequality.
Assessment of Aqueous Leaf Extracts of Parthenium Hysterophorus L. On Seedlings Growth of Wheat
Authors: Akter Nousin Akter , Rahman Md Hasanur Rahman 
Published: November 2023

An investigation was conducted to assess the effect of Parthenium hysterophorus L. leaf extracts on seedling growth of three wheat (Triticum aestivum L.) varieties viz. Sourav, BARI Gom 22 and BARI Gom 33. It was observed that the growth of wheat seedlings was significantly influenced by the Parthenium extract treatments. BARI Gom 22 showed more tolerance to Parthenium treatments than BARI Gom 33 and Sourav. Generally, wheat seedlings growth was inhibited by Parthenium extract treatments at all periods. The percent inhibition of shoot and root elongation were more visible at 5% treatment concentration at all periods than other extract treatments. On the other hand the number of root of wheat seedlings was not found to be affected by Parthenium at 7 and 10-day periods. It was also noted that the effect of Parthenium extracts on wheat seedling growth is concentrations dependent manner.
J. Bio-Sci. 31(1): 61-70, 2023
Artículo 129 de la LOSEP: un Análisis de la Incidencia Laboral y Económica en los Servidores Públicos del Ecuador
Authors: Saldarriaga-Camacho Cristina , Sigüenza-Sigüenza Hilda , Gallegos-Avendaño Mónica 
Published: November 2023

El trabajo investigativo tiene como objeto analizar la nueva reforma del artículo 129 de la Ley Orgánica del Servicio Público y la vulneración que produce a los derechos económicos y laborales de los servidores públicos en el Ecuador mediante un análisis exhaustivo. Esta investigación tiene un enfoque cualitativo descriptivo teórico ya que, al tratarse de un estudio inherente al área de la ciencia social, se buscó producir un artículo de revisión teórica narrativa con el cual se demostró los fundamentos jurídicos por los cuales el artículo 129 de la Ley Orgánica del Servicio Público menoscaba los derechos laborales y económicos de los servidores públicos jubilados en el Ecuador, siendo un hallazgo la determinación de que la referida disposición jurídica adolece de inconstitucionalidad.
El Décimo Cuarto en Ecuador y la Pensión Alimenticia: Visión Integral en la Vulneración de Derechos del Alimentante
Authors: Yaguana-Rodriguez Erika 
Published: November 2023

El derecho de recibir alimentos es un derecho fundamental para los niños, niñas y adolescentes para su etapa de crecimiento y desarrollo, además que a través de este derecho se garantizan muchos otros como, vivienda, salud, educación, alimentación, por lo tanto, sus progenitores tienen la obligación de cumplir con dichas necesidades a través del pago de una pensión alimenticia. No obstante, en dos ocasiones anuales se realiza un pago doble de dicho valor, el mismo que se enmarca en el décimo tercer sueldo y décimo cuarto sueldo. Si bien todo trabajador tiene derecho a recibir el décimo cuarto sueldo este en muchas ocasiones no es suficiente para cumplir con el valor fijado como pensión alimenticia; dado que el valor recibido es el correspondiente al salario básico unificado anual (SBU), por lo tanto se genera una vulneración de derechos para aquellos alimentantes que al tener un trabajo informal no reciben dichos beneficios, así como para quienes la pensión alimenticia es mucho más alta al SBU o responden ante otras cargas familiares, de tal manera que se deberían buscar métodos de cálculo que no afecten a los derechos de proporcionalidad e igualdad de los alimentantes.
Mystical and Archetypal Journeys in Leila Aboulela’s Bird Summons
Authors: Saleh Lina , Saleh Sabrine , Al-Shboul Yasser 
Published: November 2023

This article aims at exploring the significance of intertwining the mystical and the archetypal journey structures in Leila Aboulela’s novel, Bird Summons (2019). It highlights the author’s indebtedness to Islamic Sufi tradition and shows how she appropriates Farid ud-din Attar’s mystical pilgrimage of the seven valleys to a postmodern context where three Arab-British female characters attain spiritual transcendence. On the other hand, the article employs Joseph Campbell’s structure of the archetypal journey narratives to explicate the relationship between the narrative structure and the author’s chief thematic concerns. Campbell’s seventeen stages of the “Monomyth,” or the “hero’s journey,” illuminate Aboulela’s proficient projection of the characters’ spiritual quest in their physical movement from the city into the forest. England performs a cultural contact zone which entices the protagonists to overcome their identity crises caused by traumatic experiences, acute sense of displacement, and nostalgia. The success of their physical journey to Lady Evelyn Cobbold’s grave functions as an allegory for the redemptive impact of spirituality which ultimately empowers them to become more functional individuals and to integrate into English society. The study concludes that Aboulela’s deliberate fusion of Islamic journey structure with a Western one attests to the author’s belief in the universality of Islam and the possibility of religious tolerance and intercultural coexistence.
Utilization of purple yam skin (Ipomoea batatas L.) in the making of nata de batatas
Authors: Gafar Fahira , Oessoe Yoakhim Y.E. , Lamaega Jolanda Ch.E. 
Published: November 2023

Nata de batatas is a product of purple sweet potato peel. The presence of anthocyanin compounds in purple sweet potato skin makes this food very attractive to be processed into nata products that have functional value. The purpose of this research was to determine the yield of nata from purple sweet potato peel made with variations in the percentage of purple sweet potato peel extract and the percentage of coconut water and pellicle thickness, evaluate organoleptic properties including texture, color, aroma, taste, and determine anthocyanin levels. The results showed that the highest nata yield was 70.08%. The thickness of the largest 1.26 cm. The best anthocyanin analysis in nata was 0.47 mg. The organoleptic test showed that the color percentage of purple sweet potato peel extract and the percentage of coconut water were significantly different while the texture, aroma and taste were not significantly different.
Keywords: nata de batatas, purple sweet potato skin, coconut water, anthocyanin