bluuebunny/crossref_metadata_2025_split huggingface dataset:
C-reactive protein to albumin ratio and risk of incident metabolic syndrome in community-dwelling adults: longitudinal findings over a 12-year follow-up period
Authors: Lim Taekyeong , Lee Yong-Jae 
Published: January 2024

Abstract
Aim
The CRP-to-albumin (CRP/Alb) ratio has emerged as a novel biomarker for various inflammatory diseases. This study aimed to evaluate the association between the CRP/Alb ratio and incident metabolic syndrome (MetS) with a large-sample, community-based Korean cohort over a 12-year follow-up period.
Materials and Methods
Among 10,030 participants, a total of 6,205 participants aged 40 to 69 years without MetS were selected from the Korean Genome and Epidemiology Study (KoGES). The baseline CRP/Alb ratio was divided into quartiles. Our definition of newly developed MetS was the one proposed by the 2009 Joint Interim Statement of Circulation. Hazard ratios (HRs) with 95% confidence intervals (CIs) for incident MetS were calculated using multivariate Cox proportional hazards regression models after adjusting for potentially confounding variables.
Results
During the 12-year follow-up period, MetS developed in 2,535 subjects (40.9%, 2,535/6,205) with an incidence rate of 5.6–11.9 (over 2 years). Compared to the reference first quartiles, the HRs (95% CIs) of incident MetS in the second, third, and fourth quartiles increased in a dose-response manner. Compared to the reference quartile, the HRs (95% CIs) for the incidence of MetS for the highest quartiles of CRP/Alb ratio was 1.47 (1.31–1.65) when considering age, sex, smoking status, alcohol intake, physical activity, TG level, HDL-C, mean arterial pressure, and HOMA-IR in the multivariate analysis.
Conclusions
High CAR at baseline may be a useful surrogate indicator of future incident MetS.
Pressure Ulcer and Associated Factors Among Adult Patients Admitted To The Surgical Wards in The Comprehensive Specialized Hospital Of The Northwest Amhara Regional State, Ethiopia
Authors: Bekele Habtamu , Zemene Workie , Tesfaye Mrs.Eleny 
Published: January 2024

Abstract
Introduction: Pressure ulcers are a serious concern in patients with prolonged bedtime and present with common complications following surgery. It is one of the key performance indicators of the quality of nursing care provided to patients. and several studies have reported the prevalence of pressure ulcers in Ethiopia. There is a lack of evidence regarding its prevalence and associated factors in the current study area. The main objective of this study was to assess pressure ulcers and their associated factors among adult patients admitted to the surgical ward of the Amhara Regional Comprehensive Specialized Hospital in Northwest Ethiopia in ,2023.
Method: An institution-based, cross-sectional study was conducted from June 15 to June 19 ,2023 in NorthWest Ethiopia.and a systematic random sampling technique was used to select 480 patients . Descriptive data were presented as absolute numbers with percentages , and multivariate analysis was used to assess the statistical association between a ssociated factors and pressure ulcers . P < 0.05 indicated Statiscal significance .
Results: A total of 49 pressure ulcer cases were detected among 480 patients. a prevalence rate of 10.2%, 95% CI (7.7, 12.9). Participants who had smoked (95% CI: AOR 7.46 (2.64,21.06), were bedridden (95% CI: AOR 3.92 (1.28, 11.66), had length of hospital stay of 21days (95% CI: AOR 3.01 (1.13, 8.02), had pain (95% CI: AOR 3.20 (1.06, 7.51), or had friction and shear (95% CI: AOR 5.71 (1.91, 17.08), were found to be significant factors associated with pressure ulcers .
Conclusion: This study showed that a high percentage of Pus among patients had pressure ulcers. Smoking status, pain, bedridden status , friction and shear problems, and length of hospital stay were significantly associated with pressure ulcers . Healthcare providers should educate patients about smoking risk, pain management, mattress installation, and linen care.
AI-Embedded UAV System for Detecting and Pursuing Unwanted UAVs
Authors: KAMANLI Ali Furkan 
Published: January 2024

In recent years, the use of unmanned aerial vehicle (UAV) platforms in civil and military applications has surged, highlighting the critical role of artificial intelligence (AI) embedded UAV systems in the future. This study introduces the Autonomous Drone (Vechür-SIHA), a novel AI-embedded UAV system designed for real-time detection and tracking of other UAVs during flight sequences. Leveraging advanced object detection algorithms and an LSTM-based tracking mechanism, our system achieves an impressive 80% accuracy in drone detection, even in challenging conditions like varying backgrounds and adverse weather.
Our system boasts the capability to simultaneously track multiple drones within its field of view, maintaining flight for up to 35 minutes, making it ideal for extended missions that require continuous UAV tracking. Moreover, it can lock onto and track other UAVs in mid-air for durations of 4-10 seconds without losing contact, a feature with significant potential for security applications.
This research marks a substantial contribution to the development of AI-embedded UAV systems, with broad implications across diverse domains such as search and rescue operations, border security, and forest fire prevention. These results provide a solid foundation for future research, fostering the creation of similar systems tailored to different applications, ultimately enhancing the efficiency and safety of UAV operations. The novel approach to real-time UAV detection and tracking presented here holds promise for driving innovations in UAV technology and its diverse applications.
Kualitas Air Dan Hidrogeokimia Mata Air Di Lereng Selatan Gunungapi Merbabu
Authors: Diwijaya Sonna , Cahyadi Ahmad , Pramono Hadi Mohammad 
Published: January 2024

Mata air di lereng selatan Gunungapi Merbabu memiliki peranan yang besar dalam penyediaan air bersih bagi masyarakat di Kecamatan Selo, Kabupaten Boyolali. Penelitian ini bertujuan untuk; (1) menganalisis kualitas air pada mata air di lereng Selatan Gunungapi Merbabu, dan (2) menganalisis karakteristik hidrogeokimia air pada mata air di lereng selatan Gunungapi Merbabu. Penelitian ini dilakukan di Lereng Selatan Gunung Merbabu dengan mengambil 4 sampel mata air, 2 sampel air hujan, dan satu sampel air sungai. Penentuan titik pengambilan sampel mata air berdasarkan sensus berdasarkan data dari Balai Taman Nasional Gunung Merbabu, wawancara penduduk lokal, dan penelitian terdahulu. Analisis kualitas air dilakukan dengan metode matching terhadap baku mutu air minum Peraturan Pemerintah No. 22 Tahun 2021, Todd dan Mays (2005), dan Guidline for Drinking Water World Health Organization 2022. Analisis hidrogeokimia dilakukan dengan analisis ion mayor dominan menggunakan Schoeller Diagram, analisis tipe kimia dan proses hidrogeokimia yang dominan dengan diagram piper, serta analisis perbandingan ion untuk menentukan proses-proses yang mempengaruhi kondisi hidrogeokimia mata air termasuk sumber pencemaran. Hasil analisis menunjukkan bahwa kualitas air di lokasi kajian dalam kondisi baik. Meskipun semua parameter tidak ada yang melebihi baku mutu, tetapi indikasi terjadinya pencemaran telah terindentifikasi. Selain itu, karakteristik hidrogeokimia dari parameter DHL, TDS dan suhu, serta tipe kimia HCO3- - Ca2+- Mg2+ menunjukkan bahwa mata air disuplai dari air tanah pada akuifer dangkal dan lokal dengan proses utama pengayaan mineral pada zona lengas tanah.
Serum banks for serological survey of SARS-CoV-2 and emerging infectious diseases
Authors: Zhao Jinghui , Cong Yanlong , Li Junfeng , Sun Yixue , Wang Fengjie , Zhao Li-Feng , Xue Honghong , Guo Li , Wang Yongzhi , Li Xiaocheng , Liu Xuelian 
Published: January 2024

In June 2021, Udom et al. published their article in
Transboundary and Emerging Diseases performing a serological
survey revealed evidence of anti-N-IgG antibodies suggesting SARS-CoV-2
exposure in both dogs and cats during the first and second coronavirus
disease 2019 (COVID-19) outbreaks in Thailand. Seroprevalence studies
have proven an important tool to monitor the progression of the COVID-19
pandemic. The duration of immunity of SARS-CoV-2 is crucial for the
course of the pandemic and for this reason the monitoring of antibodies
against SARS-CoV-2 is important. The serum samples from different
periods and regions were valuable in terms of scientific significance
for serological survey of SARS-CoV-2 and emerging infectious diseases.
In order to preserve the remaining serum samples and ensure the
stability of anti-virus antibodies in storage serum samples, we strongly
suggest that standard serum banks should be established worldwide.
How can the monitoring of complement parameters help to treat angioedema due to C1-inhibitor deficiency?
Authors: Pólai Zsófia , Balla Zsuzsanna , Varga Lilian , Benedek Szabolcs , Farkas Henriette 
Published: January 2024

Background: Acquired angioedema due to C1-inhibitor deficiency
(C1-INH-AAE) is a rare disease that can be diagnosed by complement
testing. It often accompanies lymphoproliferative underlying diseases.
Methods: In the last 30 years, from the 3938 patients who were sent to
the Angioedema Center with angioedema symptoms, we have diagnosed
C1-INH-AAE in 19 cases, and monitored them regularly. The connections
between the underlying disease, its treatment, the angioedema symptoms
and complement parameters were investigated. Results: The 19 C1-INH-AAE
patients were followed up for 6 years on average. Underlying disease was
diagnosed in case of 15 patients. Most often lymphoma (6/19 patients)
and monoclonal gammopathy of undetermined significance (6/19 patients)
were found. There was no difference between the sexes regarding the
complement parameters. Connection was found between the presence and
activity of any underlying disease, the frequency of the angioedema
attacks and the decreased level of proteins of the complement system.
Angioedema specific long-term prophylaxis did not make an improvement in
neither the frequency of the attacks nor in the complement parameters.
Rituximab treatment reduced the number of attacks or completely made
them disappear, and we experienced positive changes in complement
parameters. Conclusion: Complement parameters supported the long-term
efficacy of rituximab treatment for C1-INH-AAE. The change in complement
parameters can predict the relapse of the underlying disease, and it is
a good indicator for the prediction of angioedematous attacks. In case
of C1-INH-AAE, it is significantly important to examine the patients for
underlying disease, and to regularly follow up the patient’s complement
parameters.
Peridroplet mitochondria regulated by perilipin 5 are involved in the prevention of non-alcoholic steatohepatitis in mice by Diethyldithiocarbamate
Authors: Sun Xiangyun , Kang Bilian , Zhao Xinyan , Li Hongyi , Liu Helin , Liu Lin , Wang Ping , Cong Min , Jia Jidong , You Hong , Liu Tianhui 
Published: January 2024

Background and Purpose: Diethyldithiocarbamate(DDC) alleviates hepatic
inflammation and fibrosis of methionine- and choline-deficient(MCD)
diet-induced non-alcoholic steatohepatitis(NASH) in mice. Interestingly,
increased macrovesicular steatosis replace the ballooning of hepatocytes
by DDC. The therapeutic mechanism of DDC on NASH remains unclear.
Experimental Approach: C57BL/6 mice received choline-deficient, L-amino
acid-defined(CDAA) diet to induce NASH with or without DDC
treatment. Lipidomic and microarray analyses were used to find the lipid
metabolites and genes regulated by DDC. RNAscope and immunoblotting were
used to detect perilipin 5(Plin5) in the liver. Peridroplet
mitochondria(PDM) were isolated from liver tissues, stained and observed
by confocal microscope. Mixture of Oleic and palmitic acid were used to
treat C3A cells. The effect of DDC on Plin5, mitochondria-LD contact and
mitochondrial function were analyzed. Key Results: DDC alleviated
hepatic inflammation and fibrosis, whereas steatosis increased in
CDAA-diet induced NASH. Triglyceride content and genes related to
LDs and mitochondrial function increased by DDC. Plin5 which can promote
the expansion of LD and formation of PDM was upregulated in the liver by
DDC. PDM were observed in steatotic liver and have enhanced
mitochondrial function relative to cytoplasm mitochondria. DDC increased
the size of LDs and the number of PDM, and improved mitochondrial
function both in vivo and in vitro. Conclusion and Implications: PDM
promote triglyceride synthesis and reduce lipotoxicity-induced liver
injury, inflammation and fibrosis. PDM regulated by Plin5 contribute to
the therapeutic effect of DDC on NASH. The regulation of PDM may
represent an attractive pharmacological target for NAFLD.
Exploring the diagnostic performance of MRI in the US-guided high-intensity focused ultrasound ablation for abdominal wall endometriosis
Authors: Hu Shangying , Xiao Zhibo 
Published: January 2024

This study is to explore the clinical value of magnetic resonance
imaging (MRI) in the diagnose and the treatment of abdominal wall
endometriosis (AWE) with US-guided high-intensity focused ultrasound
(USg-HIFU). MRI was performed before and after the USg-HIFU treatment.
The information about the clinical characteristics of patients, the
characteristics of lesions revealed by MRI, and the outcomes of
treatments were collected. We compared results from MRI and color
Doppler ultrasound before surgery, as well as the volume and the
apparent diffusion coefficient (ADC) values of the lesions before and
after USg-HIFU treatment. Thirty lesions in 29 patients were examined.
The locations of the 30 AWE lesions were identified by MRI. Their sizes
appeared larger in MRI results than that of ultrasound, which had a
significant difference (P < 0.05). A total of 27 lesions were
evaluated by MRI after USg-HIFU treatment, from which 92.6% (25/27)
lesions were of high or slightly high signal on T1-weighted images. They
showed annular enhancement and no contrast agent perfusion in the middle
of the lesion on post-contrast images, which obviously differ from that
in pre-operation. The other two lesions showed iso-intense signal on
T1WI with significant enhancement. The mean ADC value of AWE lesions
were (1.46±0.30) x10-3 mm2/s and (1.87±0.37) x10-3 mm2/s for pre- and
post-HIFU treatment (P < 0.05). MRI is a useful tool for
demonstrating the location, size, and concurrent changes of AWE before
and after USg-HIFU treatment, which is beneficial for follow-up
monitoring or treatments.
Comment on: Impact of diabetes status on immunogenicity of trivalent inactivated influenza vaccine in older adults
Authors: Guo Li , Sun Yixue , Li Junfeng , Cong Yanlong , Zhao Jinghui 
Published: January 2024

Recently, Spencer et al. published their interesting article
in Influenza and Other Respiratory Viruses providing evidence that there
is no impact of diabetes status on immunogenicity of trivalent
inactivated influenza vaccine in older adults. Although we agree with
the conclusion, we suggest that the transportation condition of
the serum samples should be added in the description of serological
surveys of influenza in the future. Stability of specific influenza
antibodies in sera samples stored in differing conditions should be
considered.
Optimization of continuous particle separation in a symmetric sharp corner microchannel
Authors: Mahani Moheb Amir , Naserifar Naser 
Published: January 2024

The separation of circulating tumor cells from the bloodstream with high
purity plays a crucial role in the treatment of cancer illness. Design
and fabrication of cell sorters based on numerical models can lead to
optimized cell sorters from throughput, purity, and size aspects. In
this research, a symmetric sharp corner microchannel was designed and
optimized to achieve a more compact cell sorter with high purity output
based on a numerical model. Sharp corners in the microchannel generate
centrifugal and inertial lift forces which cause particles (7.32 μm and
15.5 μm ) separation. The proposed numerical model was validated using
experimental data. Using the proposed approach decreased the size of the
device up to 19% while maintaining the purity level of 95.45%. These
results will have impacts in designing compact cell sorters with high
purity output for implantable applications.
Can we diagnose sarcopenia using anterior femoral muscle thickness in patients with cardiovascular disease?
Authors: Fukuda Taira , Yokomachi Jun , Yamaguchi Suomi , Yagi Hiroshi , Shibasaki Ikuko , Ugata Yuusuke , Sakuma Masashi , Yasuda Tomohiro , Abe Shichiro , Fukuda Hirotsugu , Fujita Hideo , Toyoda Shigeru , Nakajima Toshiaki 
Published: January 2024

Objective: Making the diagnosis of sarcopenia is not always easy and this is especially true for those with cardiovascular disease. The purpose of this study is to investigate whether it is possible to diagnose sarcopenia by using ultrasound-guided measurements of anterior femoral muscle thickness.
Methods: We investigated the utility of ultrasound-guided measurements of anterior femoral muscle thickness in 1075 hospitalized patients with cardiovascular disease (675 men). As a comparison, sarcopenia was assessed by skeletal muscle mass index using bioelectrical impedance analysis and the Asia Working Group for Sarcopenia criteria.
Results: When the receiver operating characteristic curve using muscle thickness was examined, we found this could be used to make the diagnosis of sarcopenia (men: cutoff value 2.425 cm, area under the curve 0.796; women: cutoff value 1.995 cm, area under the curve 0.746). The prevalence of sarcopenia according to the criteria with skeletal muscle mass index was 34.2% in men and 51.8% in women, while its prevalence according to the cutoff value of muscle thickness was 29.2% in men and 36.7% in women.
Conclusion: Ultrasound-guided measurement of the anterior femoral muscle thickness is a simple and useful method to help make the diagnosis of sarcopenia in patients with cardiovascular disease.
The Potential of Library Publishing Services to Transform Scholarly Communication in Ireland
Authors: Duffy Johannah 
Published: January 2024

Libraries need to move beyond traditional roles of purchasing and distributing scholarly literature, librarians need to strategically position themselves and take ownership of improving access. As a direct result of Covid-19, there is a new level of urgency to transform the scholarly communication process and there are enormous opportunities for an expanded and inclusive library publishing service which addresses access to knowledge and literature. This rich discussion will stimulate the drive to make library publishing a mainstream service within Irish libraries.
The purpose of this study is to provide a vision for how academic libraries can assume a more central role in a future where open access (OA) publishing has become the predominant model for disseminating scholarly research. This work will analyse existing trends related to Open Access policies and publishing with an emphasis on the development of repositories managed by libraries to publish and disseminate articles. These trends, coupled with emerging economic realities, will create an environment where libraries’ will assume a major role in the Open Access publishing environment. This paper will provide an insight for academic libraries and their institutions to consider a dramatic shift in the deployment of subscription financial resources from a largely closed scholarly communication system to one that provides open, unrestricted access to research.
Given the importance of scholarly publishing, a number of Irish Third level libraries have launched library publishing services including the establishment and management of high quality library published peer-reviewed open access journals and Open Educational Resources to support formal and informal scholarly communication. Librarians are also upskilling in the area of library publishing. A number of Irish Librarians have completed the Library Publishing Coalition's Library Publishing Curriculum. There is also the Library Publishing Group as part of the Library Association of Ireland. This work aims to identify and examine the factors of library publishing services that facilitate scholarly communication. The clear message from this discussion is that libraries need to include publishing in their services, advocate for open access and serve their communities and societies.
Metadata Librarians for Open Access
Authors: Chan Jennifer , Zhang Erica , Vermeij Hermine , Riemer John 
Published: January 2024

Support by academic libraries for open access (OA) over the past three-plus decades has largely focused on the development of digital infrastructure, promotion of open access publishing, support of policy-driven access mandates, and more recently, adoption of transformative agreements. Libraries have correspondingly created a broad array of scholarly communication roles to support these varied approaches. Surprisingly, one area of open access support that has received less attention from libraries is the facilitation of description and discovery of open access resources through the creation of robust original metadata. Expertise in Organization of Recorded Knowledge and Information represents a core competency of librarianship, yet the current academic library landscape shows few positions that specifically apply this expertise towards support for OA resources. Efforts to describe OA resources typically fall below those dedicated to licensed resources and pale in comparison to OA advocacy work, repository, publishing and other services. This case study offers an example of how one large academic library has introduced a metadata librarian position focused on description of open access resources into its activities supporting open access.
For decades, commercially licensed resources have benefitted from metadata enhanced layer by layer by commercial and library professionals alike. With increased focus and funding being devoted to open access driven by governmental, institutional, and private funders, attention is critically needed to ensure that these new resources obtain the description necessary to allow them to be useful. Metadata librarians focused on open access resources can work with array of positions, such as repository managers and other digital asset management professionals, to ensure that open access resources are properly ingested and managed, and that metadata practices are aligned with best practices for preservation and long-term access. OA metadata librarians could be responsible for developing and implementing metadata standards and practices for open access resources like scholarly articles, data sets, and other digital objects. These standards would help ensure that open access resources are accurately described and discoverable alongside purchased resources, making them more accessible to researchers and other users.
In addition to their technical responsibilities, OA metadata librarians can also play key roles in advocating for open access resources and educating library staff and users about the importance of metadata in supporting discoverability and accessibility. Through participation in professional organizations and initiatives focused on open access and metadata, OA metadata librarians can help raise awareness of the importance of metadata in supporting open access resources, their sustainability, and ultimately, their impact.
Informatization of Education. Media Education and Media Literacy
Authors: ANTONYAN Lilit 
Published: January 2024

Recent studies have shown that education in the 21st century cannot be imagined without using information and communication technologies, digital and media tools. As a result of teachers’ training, it has become clear that there is a need to promote teachers, ICTs, media education and media literacy.
The article presents the informatization of education, which will promote the development of professional abilities and skills of teachers, lecturers, raising public awareness and improving the quality of education.