bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nonlocal Huygens’ meta-lens for high-quality-factor spin-multiplexing imaging
Authors: Yao Jin , Fan Yubin , Gao Yunhui , Lin Rong , Wang Zhihui , Chen Mu Ku , Xiao Shumin , Tsai Din Ping 
Published: January 2025

Abstract
Combining bright-field and edge-enhanced imaging affords an effective avenue for extracting complex morphological information from objects, which is particularly beneficial for biological imaging. Multiplexing meta-lenses present promising candidates for achieving this functionality. However, current multiplexing meta-lenses lack spectral modulation, and crosstalk between different wavelengths hampers the imaging quality, especially for biological samples requiring precise wavelength specificity. Here, we experimentally demonstrate the nonlocal Huygens’ meta-lens for high-quality-factor spin-multiplexing imaging. Quasi-bound states in the continuum (q-BICs) are excited to provide a high quality factor of 90 and incident-angle dependence. The generalized Kerker condition, driven by Fano-like interactions between q-BIC and in-plane Mie resonances, breaks the radiation symmetry, resulting in a transmission peak with a geometric phase for polarization-converted light, while unconverted light exhibits a transmission dip without a geometric phase. Enhanced polarization conversion efficiency of 65% is achieved, accompanied by a minimal unconverted value, surpassing the theoretical limit of traditional thin nonlocal metasurfaces. Leveraging these effects, the output polarization-converted state exhibits an efficient wavelength-selective focusing phase profile. The unconverted counterpart serves as an effective spatial frequency filter based on incident-angular dispersion, passing high-frequency edge details. Bright-field imaging and edge detection are thus presented under two output spin states. This work provides a versatile framework for nonlocal metasurfaces, boosting biomedical imaging and sensing applications.
Understanding metastasis mixed-treatment responses through genomic analyses
Authors: Garcia-Recio Susana , Zagami Paola , Felsheim Brooke M. , Wheless Amy , Thomas Kerry , Trimarchi Renato , Carey Lisa A. , Perou Charles M. 
Published: January 2025

Abstract
Early-stage and metastatic breast cancers (MBC) can exhibit genomic heterogeneity, even within the same individual. Response to therapy in metastatic breast cancer patients with multiple metastases can also be heterogeneous, with different degrees of responsiveness to the same drug(s) across metastatic sites, termed “mixed response,” within the same patient. Whether this treatment response variability is influenced by factors such as intrinsic tumor characteristics of metastatic lesions and/or the microenvironment is unknown. Through genomic analysis of multiple metastases from the same patient, assayed in 6 different patients who had exhibited mixed response on imaging, we identified that higher regulatory T cells (T reg) and CDKN2A gene expression values correlate with non-response, while the KRAS gene, KRAS amplicon, and CD8T cells were associated with response in individual metastases. These genomic features may explain mixed clinical responses and provide valuable insights into intrapatient variations in treatment sensitivity.
Optimized convolutional neural network using African vulture optimization algorithm for the detection of exons
Authors: Jayasree K. , Hota Malaya Kumar 
Published: January 2025

Abstract
The detection of exons is an important area of research in genomic sequence analysis. Many signal-processing methods have been established successfully for detecting the exons based on their periodicity property. However, some improvement is still required to increase the identification accuracy of exons. So, an efficient computational model is needed. Therefore, for the first time, we are introducing an optimized convolutional neural network (optCNN) for classifying the exons and introns. The study aims to identify the best CNN model that provides improved accuracy for the classification of exons by utilizing the optimization algorithm. In this case, an African Vulture Optimization Algorithm (AVOA) is used for optimizing the layered architecture of the CNN model along with its hyperparameters. The CNN model generated with AVOA yielded a success rate of 97.95% for the GENSCAN training set and 95.39% for the HMR195 dataset. The proposed approach is compared with the state-of-the-art methods using AUC, F1-score, Recall, and Precision. The results reveal that the proposed model is reliable and denotes an inventive method due to the ability to automatically create the CNN model for the classification of exons and introns.
TOP2A inhibition and its cellular effects related to cell cycle checkpoint adaptation pathway
Authors: López Maria C. Arroyo , Fernández-Mimbrera M. A. , Gollini E. , Esteve-Codina A. , Sánchez A. , Ortega Juan Alberto Marchal 
Published: January 2025

Abstract
In this study, we investigate the G2 checkpoint activated by chromosome entanglements, the so-called Decatenation Checkpoint (DC), which can be activated by TOP2A catalytic inhibition. Specifically, we focus on the spontaneous ability of cells to bypass or override this checkpoint, referred to as checkpoint adaptation. Some factors involved in adapting to this checkpoint are p53 and MCPH1. Using cellular models depleted of p53 or both p53 and MCPH1 in hTERT-RPE1 cells, we analyzed cell cycle dynamics and adaptation, segregation defects, apoptosis rate, and transcriptional changes related to prolonged exposure to TOP2A inhibitors. Our findings reveal that cell cycle dynamics are altered in MCPH1-depleted cells compared to control cells. We found that MCPH1 depletion can restore the robustness of the DC in a p53-negative background. Furthermore, this research highlights the differential effects of TOP2A poisons and catalytic inhibitors on cellular outcomes and transcriptional profiles. By examining the different mechanisms of TOP2A inhibition and their impact on cellular processes, this study contributes to a deeper understanding of the regulation and physiological implications of the DC and checkpoint adaptation in non-carcinogenic cell lines.
Identification and suppression of low-frequency oscillations using PMU measurements based power system model in smart grid
Authors: Zuhaib Mohd , Rihan Mohd , Gupta Saket , Sufyan Marwan Ahmad Abdullah 
Published: January 2025

Abstract
Low-frequency oscillations (LFO) are inherent to large interconnected power systems. Timely detection and mitigation of these oscillations is essential to maintain reliable power system operation. This paper presents a methodology to identify and mitigate low-frequency oscillations ( forced and inter-area) using a wide area monitoring system (WAMS) based power system model utilizing phasor measurement units (PMUs). These models accurately identify the behavior and location of generators contributing to low-frequency oscillations in real-time and hence can efficiently improve the performance of WADC to mitigate them. The proportional resonant power system stabilizer (PR-PSS) is utilized to suppress these LFOs, as determined from the Wide Area Power System Model. The damping structure based on PR-PSS with measurements from WAMS effectively suppresses both forced and inter-area oscillation modes.
An Integrative lifecycle design approach based on carbon intensity for renewable-battery-consumer energy systems
Authors: Song Aoye , Zhou Yuekuan 
Published: January 2025

Abstract
Driven by sustainable development goals and carbon neutrality worldwide, demands for both renewable energy and storage systems are constantly increasing. However, the lack of an appropriate approach without considering renewable intermittence and demand stochasticity will lead to capacity oversizing or undersizing. In this study, an optimal design approach is proposed for integrated photovoltaic-battery-consumer energy systems in the form of a m2-kWp-kWh relationship in both centralized and distributed formats. Superiorities of the proposed matching degree approach are compared with the traditional uniformity approach, in photovoltaic capacity, battery capacity, net present value and lifecycle carbon intensity. Results showed that the proposed method is superior to the traditional approach with higher net present value and lower carbon intensity. Furthermore, the proposed method can be scaled and applied to guide the design of photovoltaic-battery-consumer energy systems in different climate zones, promoting sustainable development and carbon neutrality globally.
Circadian Phase Assessment of Core Body Temperature Using a Wearable Temperature Sensor Under the Real World
Authors: Kubota Naoko , Okada Kazufumi , Yamanaka Yujiro 
Published: January 2025

Abstract
Objective To evaluate whether a patch-type wearable temperature sensor (CALERA Research) could determine the circadian phase of core body temperature (CBT) in a manner like a rectal probe.
Materials and Methods Sixteen participants (27 ± 11 years, 8 males and 8 females) wore an actigraph and CALERA Research sensor on the chest region for 3–5 days in a real-world setting. Simultaneous rectal temperature measurements were performed during the nocturnal sleep period. The midpoints of the nocturnal decrease in CBT (CBTtrough) were used as the circadian phase marker. We analyzed 60 pairs of CBTtrough. The reliability and agreement of the CBTtrough from the two devices were analyzed using the intraclass correlation coefficient (ICC) and the concordance correlation coefficient (CCC). The Bland-Altman analysis was used to quantify the limit of agreement of CBTtrough between the devices.
Results The ICC of 0.96 (95%CI: 0.93–0.98) and CCC of 0.96 (95%CI: 0.93–0.97) values indicated excellent reliability and substantial agreement, respectively. The mean bias was 0.16 hours (95%LoA: -0.76–1.07 hours). The mean CBTtrough comparison was 5.9 ± 1.6 hours in the CALERA Research sensor and 5.8 ± 1.7 hours in the rectal probe.
Conclusion The difference in the CBTtrough between the two devices was about ± 1.0 hour which would be an acceptable range for determining the CBTtrough. We suggest that the CALERA Research sensor could be a useful tool for reasonably estimating the circadian phase of CBTtrough and providing a surrogate for a rectal probe.
Complications of Gastrostomy Tube Placement
Authors: Peters Gail , Bittman Ross , Sankhla Tina 
Published: January 2025

AbstractGastrostomy tube placement is a common medical procedure performed endoscopically, surgically, or with image guidance in interventional radiology. It is indicated for nutritional supplementation in those with inadequate oral intake and for gastric decompression in the setting of intestinal obstruction. For optimal outcomes, preprocedural clinical evaluation, imaging workup, meticulous technique during placement, and close clinical follow-up are essential. Complications are usually minor but not uncommon. They may occur during placement, in the immediate postoperative period, and throughout the time the tube is in place. This article will review the indications, contraindications, and complications of percutaneous gastrostomy tube placement. Major and minor complications will be illustrated along with tips and mitigation strategies employed to avoid and treat them.
Cytoplasmic Vacuoles in Lymphocytes of a Child with Sialic Acid Storage Disorder
Authors: Shafi Saba , Kahwash Samir B. 
Published: January 2025

AbstractThis is an image-based clinical vignette demonstrating unusual cytoplasmic vacuoles in the lymphocytes in a stained peripheral blood smear from a 6-month-old infant who presented with seizures, hypotonia, and hepatosplenomegaly and was found to have the extremely rare lysosomal disorder, namely, sialic acid storage disease. Although not specific, it is important to recognize this morphologic finding for reflex biochemical and genetic testing.
Tracing the development of the perfect alternation in Early Modern English
Authors: Hundt Marianne , Iyieri Yoko 
Published: January 2025

Abstract
On the basis of just under 5,050 examples of perfect constructions, this paper traces the development of the
be:have perfect alternation in English between the 1620s and 1750s. For a core group of 18 verbs, the study
investigates the role that language-internal and language-external predictor variables played in the choice of auxiliary.
Multifactorial modelling reveals that language-internal factors such as modality, negation, clause-type and tense are among the
most important predictors favouring the choice of have as auxiliary; there is also some indication of diachronic, lexical
and idiosyncratic variation within Early Modern English. A close investigation of perfects that combine both auxiliaries
strengthens the view that ambiguity-avoidance did not play a major role in the loss of the be-perfect. The results of the
multifactorial model suggest greater independence of negation and counterfactuality as factors than previously claimed. The study
thus contributes a novel perspective on the demise of the be-perfect, with paradigmatic variability taking centre
stage.
Researching the role of interaction in young learners’ acquisition of English
Authors: Shintani Natsuko , del Pilar García Mayo María 
Published: January 2025

Abstract
In this interview, Natsuko Shintani, the Review Editor of Language Teaching for Young Learners,
invites Dr. María del Pilar García Mayo to share her expertise as a teacher and researcher. Dr. García Mayo is a Full Professor of
English Language and Linguistics at the Universidad del País Vasco (UPV/EHU). She is highly regarded for her extensive research on
language teaching and learning for young learners in EFL contexts, with a particular emphasis on the L2/L3 acquisition of English
morphosyntax and, more recently, the role of conversational interaction in young learners’ acquisition of English. She has led
numerous research projects focused on young learners and has supervised many Ph. D. and Master’s theses, several of which centre
on this area of study. See her webpage (https://laslab.org/staff/pilar/)
for more information.
Reply to the Comment on ‘Klein–Gordon particles in a quasi-pointlike global monopole spacetime and a Wu-Yang magnetic monopole: invariance and isospectrality’
Authors: Mustafa Omar 
Published: January 2025

Abstract
In his Comment the author claims that we have modified the boundary conditions at the origin for the shifted harmonic oscillator and consequently solved a completely different problem in section 7 of J. Phys. G: Nucl. Part. Phys. 51 (2024) 055201. In the current reply, we shall show that the Fernandez claims are incorrect.
Invasiveness of pico- and nanosecond E-FISH on plasma bullets in nitrogen
Authors: Limburg Anne , Keur Thijs , Pleijers Ramón , Nijdam Sander 
Published: January 2025

Abstract
The electric field is the driving force behind every plasma. Electric field induced second harmonic generation (E-FISH) is a diagnostic able to obtain the electric field with high temporal and spatial resolution, is considered non-invasive and can be applied to almost any type of plasma with high sensitivity. However, the high fluence laser beam used as a probe in this technique, can interact with the gas and induce charges, which can subsequenly influence the plasma. In this work, E-FISH is applied on non-thermal pulsed plasma jets in N2 flowing into atmospheric air. In these jets, ionization fronts propagate along the axis of the jet, which are highly reproducible and periodic. This allows for phase resolved measurements. A nanosecond and a picosecond pulsed laser, both operating at 1064 nm, are used as a source. For the first time, the obtained E-FISH signals measured with both lasers are compared to each other. The results deviate significantly between the two lasers, which can be explained by induced laser guiding. This is observed by taking ICCD images of the plasma trajectory. At the position where the plasma crosses the laser beam path, the plasma branches. This reveals that E-FISH is also invasive under some conditions. The profiles obtained with the picosecond laser are in good qualitative agreement with previous CRS-based FWM results on the same plasma source and therefore the picosecond laser is considered non-invasive. In future E-FISH measurements, the influence of the laser beam on the E-FISH signal should be taken into account to prevent changing the plasma behavior. By decreasing the laser power or using a shorter laser pulse, succesfull measurements can be performed.
Vlasov-Poisson simulation study of phase-space hole coalescence in a cylindrically wave-guided plasma
Authors: Lobo Allen , Kumar Sayal Vinod 
Published: January 2025

Abstract
In this work, coalescence of phase-space holes of collision-less, one-dimensional plasmas is studied using kinetic simulation techniques. Phase-space holes, which are well-known Bernstein-Greene-Kruskal waves known for exhibiting coalescence, are numerically simulated and their coalescence is observed. Relations between the hole speed, potential, phase-space vorticity and phase-space depth are then obtained using the simulation data. This study involves the study of electron phase-space hole coalescence in a cylindrically wave-guided plasma. Using the recently developed phase-space hydrodynamic analogy, it is shown that the coalescence phenomena can be explored in terms of the fluid-analogous vortical nature of the phase-space holes. Coalescence occurs due to the interaction of the phase-space velocity fields associated with these phase-space vortices. Results obtained from the study describes various parametric relations between the coalesced hole characteristics and the characteristics of the colliding holes.
ELG spectroscopic systematics analysis of the DESI Data Release 1
Authors: Yu J. , Ross A.J. , Rocher A. , Alves O. , de Mattia A. , Forero-Sánchez D. , Kneib J. , Krolewski A. , Lan T.-W. , Rashkovetskyi M. , Aguilar J. , Ahlen S. , Bailey S. , Brooks D. , Chaussidon E. , Claybaugh T. , de la Macorra A. , Dey Arjun , Dey Biprateep , Doel P. , Fanning K. , Forero-Romero J.E. , Gaztañaga E. , Gontcho S.Gontcho A. , Honscheid K. , Howlett C. , Juneau S. , Kisner T. , Kremin A. , Lambert A. , Landriau M. , Le Guillou L. , Levi M.E. , Manera M. , Martini P. , Meisner A. , Miquel R. , Moustakas J. , Mueller E. , Muñoz-Gutiérrez A. , Myers A.D. , Nie J. , Niz G. , Palanque-Delabrouille N. , Percival W.J. , Poppett C. , Prada F. , Rezaie M. , Rossi G. , Sanchez E. , Schlafly E.F. , Schlegel D. , Schubnell M. , Seo H. , Sprayberry D. , Tarlé G. , Weaver B.A. , Zarrouk P. , Zhao C. , Zhou R. , Zou H. 
Published: January 2025

Abstract
Dark Energy Spectroscopic Instrument (DESI) uses more than 2.4 million Emission Line Galaxies (ELGs) for 3D large-scale structure (LSS) analyses in its Data Release 1 (DR1). Such large statistics enable thorough research on systematic uncertainties. In this study, we focus on spectroscopic systematics of ELGs. The redshift success rate (f
goodz) is the relative fraction of secure redshifts among all measurements. It depends on observing conditions, thus introduces non-cosmological variations to the LSS. We, therefore, develop the redshift failure weight (w
zfail) and a per-fibre correction (η
zfail) to mitigate these dependences. They have minor influences on the galaxy clustering. For ELGs with a secure redshift, there are two subtypes of systematics: 1) catastrophics (large) that only occur in a few samples; 2) redshift uncertainty (small) that exists for all samples. The catastrophics represent 0.26% of the total DR1 ELGs, composed of the confusion between [O ii] and sky residuals, double objects, total catastrophics and others. We simulate the realistic 0.26% catastrophics of DR1 ELGs, the hypothetical 1% catastrophics, and the truncation of the contaminated 1.31 < z < 1.33 in the AbacusSummit ELG mocks. Their P
ℓ
show non-negligible bias from the uncontaminated mocks. But their influences on the redshift space distortions (RSD) parameters are smaller than 0.2σ. The redshift uncertainty of DR1 ELGs is 8.5km s-1 with a Lorentzian profile. The code for implementing the catastrophics and redshift uncertainty on mocks can be found in https://github.com/Jiaxi-Yu/modelling_spectro_sys.
Blinding scheme for the scale-dependence bias signature of local primordial non-Gaussianity for DESI 2024
Authors: Chaussidon E. , de Mattia A. , Yèche C. , Aguilar J. , Ahlen S. , Brooks D. , Claybaugh T. , Cole S. , de la Macorra A. , Doel P. , Fanning K. , Gaztañaga E. , Gontcho S.Gontcho A. , Howlett C. , Kisner T. , Lambert A. , Le Guillou L. , Manera M. , Meisner A. , Miquel R. , Niz G. , Palanque-Delabrouille N. , Percival W.J. , Prada F. , Ross A.J. , Rossi G. , Sanchez E. , Schlegel D. , Schubnell M. , Seo H. , Sprayberry D. , Tarlé G. , Vargas-Magaña M. , Weaver B.A. , Zou H. 
Published: January 2025

Abstract
The next generation of spectroscopic surveys is expected to achieve an unprecedented level of accuracy in the measurement of cosmological parameters. To avoid confirmation bias and thereby improve the reliability of these results, blinding procedures become a standard practice in the cosmological analyses of such surveys. Blinding is especially crucial when the impact of observational systematics is important relative to the cosmological signal, and a detection of that signal would have significant implications. This is the case for local primordial non-gaussianity, as probed by the scale-dependent bias of the galaxy power spectrum at large scales that are heavily sensitive to the dependence of the target selection on the imaging quality, known as imaging systematics. We propose a blinding method for the scale-dependent bias signature of local primordial non-gaussianity at the density field level which consists in generating a set of weights for the data that replicate the scale-dependent bias. The applied blinding is predictable, and can be straightforwardly combined with other catalog-level blinding procedures that have been designed for the baryon acoustic oscillation and redshift space distortion signals. The procedure is validated through simulations that replicate data from the first year of observation of the Dark Energy Spectroscopic Instrument, but may find applications to other upcoming spectroscopic surveys.