bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pengaruh Tuberkulosis terhadap Kejadian Stunting pada Balita di Asia: Systematic Literature Review
Authors: Ariesta Haura Inas , Nurhaliza Putri , Putri Ineuke Rizky , Ardani Ilyasa Divanri Wisa , Herbawani Chahya Kharin 
Published: February 2025

Latar Belakang: Asia menduduki peringkat pertama dalam kejadian stunting, dengan total 52% atau 76,6 juta anak di bawah lima tahun mengalami stunting. Salah satu faktor risiko stunting adalah riwayat penyakit infeksi. Tuberkulosis sebagai penyakit menular masih menjadi masalah kesehatan di Asia Tenggara hingga saat ini, dengan jumlah kasus sebesar 46%. Tuberkulosis memiliki gejala penurunan berat badan, yang jika terjadi dalam jangka waktu lama dan tidak segera ditangani dapat mempengaruhi status gizi bahkan berkembang menjadi stunting. Penelitian ini bertujuan untuk mengetahui pengaruh tuberkulosis terhadap kejadian stunting pada balita di Asia.
Metode: Metode yang digunakan dalam penulisan artikel ini adalah metode Systematic Literature Review dengan pedoman PRISMA (Preferred Reporting Item for Systematic Review and Meta-Analysis) dengan menggunakan 3 database, yaitu Google Scholar, Pubmed, dan Mendeley. Penelitian ini berfokus pada artikel-artikel dari tahun 2019-2024 yang dapat diakses secara terbuka. Kriteria inklusi dari Systematic Literature Review ini adalah artikel yang membahas tentang tuberkulosis sebagai penyebab stunting pada anak di Asia.
Hasil: Dari 18.168 artikel yang diidentifikasi, 181 artikel memenuhi kriteria inklusi, dan 9 artikel dianalisis secara mendalam, dan menemukan bahwa tuberkulosis secara signifikan dapat menurunkan nafsu makan, yang menyebabkan asupan nutrisi yang tidak memadai, malabsorpsi, dan peradangan sistemik, yang semuanya berkontribusi terhadap stunting.
Kesimpulan: Anak-anak yang terpapar TBC lebih rentan mengalami stunting karena penurunan nafsu makan, peradangan sistemik, dan efek samping jangka panjang. Meskipun beberapa penelitian tidak menemukan hubungan yang signifikan, faktor-faktor seperti rendahnya prevalensi TBC dan cakupan imunisasi yang tinggi dapat mempengaruhi hasilnya.
ТИПОВІ СЛІДЧІ СИТУАЦІЇ ПОЧАТКОВОГО ЕТАПУ РОЗСЛІДУВАННЯ ПРИВЛАСНЕННЯ, РОЗТРАТИ МАЙНА АБО ЗАВОЛОДІННЯ НИМ ШЛЯХОМ ЗЛОВЖИВАННЯ СЛУЖБОВИМ СТАНОВИЩЕМ, УЧИНЕНОГО ОРГАНІЗОВАНОЮ ГРУПОЮ
Authors: Ярошенко Р. В. 
Published: February 2025

Наукова стаття присвячена дослідженню типових слідчих ситуацій, що виникають під час розслідування привласнення, розтрати майна або заволодіння ним шляхом зловживання службовим становищем, учиненого організованою групою, із визначенням найбільш сприятливих, серед яких слідча ситуація, коли факт протиправної діяльності виявляється та документується оперативними підрозділами, а потім кримінальне провадження реєструється на підставі зібраних матеріалів про обставини кримінального правопорушення, які надійшли в порядку ст. 214 КПК України. Серед них також виявлення факту привласнення, розтрати майна або заволодіння ним шляхом зловживання службовим становищем, учиненого організованою групою, слідчим самостійно; кримінальне правопорушення, кваліфіковане за ч. 5 ст. 191 КК України, виявлено за заявами осіб, яким стало відомо про обставини його вчинення; кримінальне правопорушення, кваліфіковане за ч. 5 ст. 191 КК України, виявлено за матеріалами перевірок Держаудитслужби; кримінальне правопорушення, кваліфіковане за ч. 5 ст. 191 КК України, виявлено за повідомлення ЗМІ та з інших джерел, передбачених законодавством. У представленій роботі значну увагу приділено питанню підслідності, розглянута нормативно-правова база з цього приводу та сучасна судово-слідча практика за матеріалами привласнення, розтрати майна або заволодіння ним шляхом зловживання службовим становищем, учиненого організованою групою. Зазначено випадки, коли матеріали за фактами кримінальних правопорушень, передбачених статтями 191 КК України, передаються на досудове розслідування Національному антикорупційному бюро України.
Unsteady Magneto-radiative Flow of Copper-water Nanofluid Over an Exponentially Stretching Surface
Authors: Tshivhi Khodani Sherrif , Tshehla Maashutha Samuel 
Published: February 2025

Understanding the complex behavior of fluid flows under various physical influences is crucial for advancing engineering and industrial applications. This paper presents the investigation of the unsteady, incompressible, single-phase magneto-radiative flow of a copper-water nanofluid over an exponentially stretching surface, considering the effects of viscous dissipation and temperature-dependent heat sources. This model, proposed in the present analysis, is based on fundamentals of the continuity and Navier–Stokesequations with mass conservation. Further, use of a similarity transformation will reduce the equations to dimensionless form and provide a numerical solution using the Runge–Kutta–Fehlberg method. In physics, engineering, and industrial applications, the most interesting parameters are the velocity, temperature, skin friction, and the Nusselt number (Nu). The results of this study are compared with previous works, showing significant agreement with findings under similar conditions. The analysis reveals that both temperature and velocity boundary layer increase when all very specific effects of radiation (R), heat source (Q), copper nanoparticle volume fraction, and magnetic field strength parameter are present. On the other hand, it is found that skin friction increases when considering both copper nanoparticle volume fraction and magnetic field strength parameter, but the Nu decreases if R, Q, copper nanoparticle volume fraction, and magnetic field strength parameter are the factors responsible for that. These outcomes will be further delineated through graphics and be elaborated in engineering and industrial context.
Comparative evaluation of Acheta domesticus and Hermetia illucens as alternative protein sources for the growth, health, and meat quality of the broiler
Authors: Mustafa Farwa , Sajjad Asif , Sajjad Muhammad , Ali Mudssar , Bashir Hafiza Sehrish , Abbas Muhammad Ghazanfar , Binyameen Muhammad , Mozūratis Raimondas 
Published: February 2025

IntroductionInsects are receiving increasing attention due to their potential to enhance farming efficiency and sustainability, mitigate vast quantities of bio-waste, and improve animal performance. It is hypothesized that replacing soybean meal with Acheta domesticus will improve broiler productive performance, health, and meat quality. Therefore, the objective of this study was to assess the effect of the gradual replacement of soybean meal (4%, 8%, and 12%) with house cricket (A. domesticus) and black soldier fly (Hermetia illucens) on productive performances, hematology, intestinal morphology, and meat quality attributes of male broiler (Ross 308). MethodsA total of 350 1-day-old chicks (39.23 ± 0.19 g) were divided into seven groups (five pens per group and 10 chicks per pen) following a completely randomized design. The seven groups included 4%, 8%, and 12% SBM replacements with A. domesticus and H. illucens. Soybean meal was the basal diet considered the control. ResultsThe broilers fed 12% A. domesticus, or 12% H. illucens had significantly higher ((p 0.05) live weight, average daily weight gain, and improved feed conversion ratio than the broilers fed basal (SBM) diet throughout starter, grower, and finisher phases. Hematology (complete blood count and serum biochemistry traits) and intestinal morphology (villus height, villus width, crypt depth, and villus height-to-crypt depth ratio) of the broilers improved when fed on 12% A. domesticus and 12% H. illucens meals as compared to the control group (p &lt; 0.05). Feeding 12% A. domesticus and 12% H. illucens also had a significant positive impact on the meat quality traits of broilers, such as maximum redness (a*) and yellowness (b*) with minimal cooking loss and lightness (L*) (p &lt; 0.05) than the broilers fed the control diet. DiscussionUsing insect meal as an alternative to traditional feed sources could contribute significantly to the sustainable expansion of the poultry industry.
Molecular characterization, chemical profile and biological properties of essential oils from Chamaemelum nobile (L.) flowers of Morocco: in vitro and in silico studies
Authors: El-Assri El-Mehdi , El-Assri Youssef , El Brahimi Rajae , El fadili Mohamed , Baghouz Asmae , Abuelizz Hatem A. , Er-Rahmani Sara , Lahkimi Amal , Bouia Abdelhak 
Published: February 2025

IntroductionThis study investigated the antioxidant, antimicrobial, and insecticidal properties of Chamaemelum nobile (L.) essential oil (CN-EO), harvested in Taounate, Morocco. The molecular composition and chemical profile of CN-EO were also characterized.MethodsThe CN-EO was extracted using a Clevenger apparatus. Its chemical composition was analyzed using gas chromatography-mass spectrometry (GC-MS). Antioxidant activity was evaluated using the DPPH assay, while antimicrobial properties were assessed via the disk diffusion method to measure inhibition zones against various bacterial and fungal strains. Insecticidal activity was tested through bioassays to determine insect mortality and repellency rates. Phylogenetic analysis of DNA sequences was conducted to confirm the species identity.ResultsGC-MS analysis identified 24 compounds in CN-EO, with β-Oplopenone (18.66%), Spathulenol (14.90%), and Himachalene (12.47%) as major constituents. CN-EO exhibited strong antioxidant activity (IC50 = 135.8 ± 1.03 μg/mL). Antimicrobial assays revealed inhibition zones of up to 20.67 ± 0.58 mm (Staphylococcus aureus) and antifungal inhibition of 40.42% ± 2.82% against Aspergillus flavus. Insecticidal tests showed total insect mortality at 166 µL/L within 48 h and a 60% repellent effect. Phylogenetic analysis of the DNA sequence revealed a 99.22% similarity with Chamaemelum nobile (L.).ConclusionThese results demonstrate the significant potential of Moroccan CN-EO in phytomedicine. It exhibits a wide range of biological activities and shows great promise as a natural antioxidant, antimicrobial agent, antifungal, and insecticide.
Knowledge, attitude, and perception of Pakistani populations toward monkeypox: a cross-section study
Authors: Yousaf Humayun , Qadeer Abdul , Sohail Muhammad , Khan Maqbool , Farooq Muhammad , Khan Zakir , Fouad Dalia , Liu Yu-Chia , Chen Chien-Chin 
Published: February 2025

ObjectiveThe reappearance of monkeypox in non-endemic countries has preceded critical public health concerns. The public’s adherence to preventative measures is influenced by their understanding of the infectious monkeypox virus (Mpox), attitude toward it, and perceptions of it. We conducted this study to evaluate the general population’s knowledge, attitude, and perceptions of Mpox in Pakistan.MethodsFrom August 15 to August 30, 2022, 3465 participants in this cross-sectional study provided information via an online survey. The survey has 37 questions divided into four categories: sociodemographic, knowledge, attitude, and perceptions of Mpox. Statistical analyses were performed in Jupyter Notebook using Python 3 and the Pandas, Matplotlib, and stats libraries.ResultsThe chi-square test and regression analysis evaluated factors related to Mpox knowledge, attitude, and perception of three thousand four hundred sixty-five participants. Among the participants, about 79.51% (2755) were male, and 32.99% (1143) had post-graduation level education. About 521(99.24) participants with post-graduation education have positive knowledge with a p-value of 0.0001. Approximately 66.78% (2314) of participants answered that Mpox is prevalent in African countries. Almost 85.69% (2969) stated that a virus causes Mpox, and more than 72.18% (2501) said that Mpox spreads through contaminated surfaces. About 60.52% (2097) of participants answered that antivirals are required in treating Mpox patients. Around more than half of the participants, 52.64% (1824), believe that those who receive the chickenpox vaccination are protected against Mpox. It’s interesting to note that most research participants felt favorably about Mpox. Around 90.22% (3126) of participants believed Mpox would be effectively eradicated. Most participants, 86.7% (3004), believe that people should care more about one another nowadays, and 81.36% (2819) believe visiting areas with a Mpox outbreak is risky. About 83.95% (2909) answered that during interaction with the Mpox patient, they’d dress in the appropriate personal protective clothing, like masks, gloves, and gowns. At the same time, 77.66% (2691) responded that they would perform hand hygiene after touching the patients’ surroundings, like beds, tables, doors, etc.ConclusionsMaximum research participants showed good attitudes and knowledge about Mpox. However, it is essential to start and execute a planned planning framework for public health awareness to avoid the occurrence and spread of Mpox in Pakistan.
Diverse vaginal microbiota in healthy Japanese women: a combined relative and quantitative analyses
Authors: Ito Masahiro , Kataoka Misaki , Sato Yoichi , Nachi Hideki , Nomoto Koji , Okada Nobuhiko 
Published: February 2025

IntroductionThis cross-sectional study aimed to characterize the viable vaginal microbiota and identify host factors influencing this microbiota by employing a combination of relative and quantitative analyses.MethodsTwenty-four vaginal fluid samples were collected from healthy adult Japanese women for analysis. Vaginal fluid pH was measured using a portable pH meter. DNA was extracted from the vaginal fluid, and the 16S ribosomal RNA gene sequences in the V3-V4 regions were analyzed to identify bacterial species. Additionally, the vaginal fluid was cultured on four types of selective agar plates. The predominant species in the growing colonies were identified using colony polymerase chain reaction, and the colonies were counted.ResultsThe vaginal microbiota was classified into four categories based on the characterization of the dominant bacterial population: Lactobacillus crispatus, Lactobacillus iners, Lactobacillus gasseri, and a diversity group. The predominant bacterial species were consistent across methods; however, the levels of the viable population varied significantly. Body mass index had a significant influence on the total number of viable bacteria and vaginal pH, while age only affected vaginal pH.ConclusionsOur findings indicate that the vaginal microbiome of healthy Japanese women is not only highly diverse but also affected by host factors such as BMI and age.
Roles of the rpoEc-chrR-chrA operon in superoxide tolerance and β-lactam susceptibility of Stenotrophomonas maltophilia
Authors: Ku Ren-Hsuan , Lu Hsu-Feng , Li Li-Hua , Yeh Ting-Yu , Lin Yi-Tsung , Yang Tsuey-Ching 
Published: February 2025

IntroductionThe rpoE-chrR pair is a regulatory system used by photosynthetic microorganisms to overcome singlet oxygen stress. rpoE and chrR encode the sigma factor σE and anti-sigma factor ChrR, respectively. Stenotrophomonas maltophilia, an opportunistic pathogen, is a multidrug-resistant gram-negative bacterium. Although it is not a photosynthetic microorganism, a rpoE-chrR homolog (smlt2377-smlt2378) was found in the S. maltophilia genome. In this study, we aimed to assess the significance of σEc-ChrR pair in oxidative stress alleviation and antibiotic susceptibility of S. maltophilia KJ.MethodsReverse transcription-polymerase chain reaction was used to validate the presence of operon. The contribution of rpoEc-chrR-chrA operon to oxidative stress alleviation and antibiotic susceptibility was evaluated using mutant constructs and stress-tolerance assays. RNA-seq transcriptome assay of wild-type KJ, KJΔChrR (chrR mutant), and KJΔChrRΔRpoEc (chrR/rpoEc double mutant) was performed to reveal the σEc regulon.ResultsThe rpoEc-chrR pair and downstream chrA formed an operon. Inactivation of chrR upregulated the expression of rpoEc-chrR-chrA operon in an σEc- and ChrA-dependent manner. σEc activation contributed to superoxide tolerance and increased β-lactam susceptibility but did not affect the tolerance to singlet oxygen and hydrogen peroxide. Transcriptome analysis revealed that expression of the nine-gene cluster, smlt2375-smlt2367, was significantly upregulated in KJΔChrR and reverted to the wild-type level in KJΔChrRΔRpoEc. smlt2375-smlt2367 cluster was located upstream of the rpoEc-chrR-chrA operon and divergently transcribed, seeming to be involved in membrane lipid modification. Deletion of smlt2375-smlt2367 cluster from the chromosome of KJΔChrR reverted the superoxide tolerance and β-lactam susceptibility to the wild-type level.DiscussionThe rpoEc-chrR pair of S. maltophilia was involved in superoxide tolerance and β-lactam susceptibility. Notably, a novel regulatory circuit involving rpoEc-chrR-chrA operon and smlt2375-smlt2367 cluster was revealed.
Successful rescue of a patient with cardiogenic shock following traumatic cardiac arrest using VA-ECMO after air medical transport: a case report
Authors: Wu Haohao , Lan Pin , Zhou Kechun , Xie Lutao 
Published: February 2025

BackgroundTraumatic cardiac arrest (TCA) poses significant challenges in resuscitation, with extremely high mortality rates, making it a critical issue in emergency and critical care medicine. Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has emerged as a crucial rescue technology for patients with cardiac arrest, providing short-term support for cardiopulmonary failure. However, the successful application and related clinical experience of VA-ECMO in TCA remain limited and require further investigation.Case presentationA male patient sustained a stab wound to the left lower limb, resulting in femoral artery and vein injuries, massive hemorrhage, and subsequent hemorrhagic shock. The patient experienced cardiac arrest upon admission to a local hospital. Following cardiopulmonary resuscitation (CPR) and emergency femoral vascular reconstruction surgery, spontaneous circulation was temporarily restored, but the patient remained hemodynamically unstable postoperatively. Initial treatment at the local hospital was ineffective. On the second morning, the patient was transferred to our hospital via air medical transport, with a transport time of 35 min. Upon arrival, the patient was promptly evaluated, and VA-ECMO support was initiated within 17 min. After 3 days of VA-ECMO support and 5 days of mechanical ventilation, the patient was successfully weaned from life support and discharged in good condition.ConclusionVA-ECMO can significantly improve the survival outcomes of patients with cardiogenic shock following traumatic cardiac arrest. The use of interhospital air medical transport effectively reduces rescue time, providing critical opportunities for the timely management of severely ill patients.
Use of a wearable device to improve sleep quality
Authors: Moore Susan L. , Carey Evan P. , Finikiotis Kristyna , Ford Kelsey L. , Zane Richard D. , Green Katherine K. 
Published: February 2025

ObjectivesThe present study aimed to analyze the effects of the use of a digital wellness device on improving sleep through reducing environmental noise.MethodsFifty-five self-reported light or moderate sleepers with difficulty falling or staying asleep due to environmental noise participated in the study. Objective sleep architecture data were collected via a wireless electroencephalogram (EEG) sleep monitor and subjective data were obtained through analysis of daily sleep diaries and responses to study-specific user experience surveys. Four primary outcomes specified a priori were analyzed for statistical significance: objectively measured sleep onset latency (SOL), wake after sleep onset (WASO), number of awakenings, and perceived SOL. Exploratory analysis through descriptive statistics was conducted for an additional 36 secondary outcomes.ResultsUse of the digital wellness device was associated with reduced SOL both objectively and subjectively. Perceived SOL was 32.5% reduced (p &lt; 0.001, difference in means 7.5 min, 95% CI 22.3%–41.4% faster), and objectively measured SOL was 13.3% reduced (p = 0.030, difference in means 2.7 min, 95% CI = 1.4%–23.8% faster). No statistically significant differences were found for other primary outcomes. Among the subjective secondary outcomes, 100% of participants felt the device blocked environmental noise, 86% reported falling asleep more easily, 76% felt they stayed asleep longer, and 82% felt overall sleep quality was improved. No differences were observed among objectively measured secondary outcomes.ConclusionsParticipants fell asleep faster when using the wearable wellness device. Participants also perceived sleep quality improvements with the intervention, although no objective differences were measured. These findings show promise for using noise-masking digital wellness devices in noisy environments to improve sleep quality.
The externalization of internal experiences in psychotherapy through generative artificial intelligence: a theoretical, clinical, and ethical analysis
Authors: Haber Yuval , Hadar Shoval Dorit , Levkovich Inbar , Yinon Dror , Gigi Karny , Pen Oori , Angert Tal , Elyoseph Zohar 
Published: February 2025

IntroductionExternalization techniques are well established in psychotherapy approaches, including narrative therapy and cognitive behavioral therapy. These methods elicit internal experiences such as emotions and make them tangible through external representations. Recent advances in generative artificial intelligence (GenAI), specifically large language models (LLMs), present new possibilities for therapeutic interventions; however, their integration into core psychotherapy practices remains largely unexplored. This study aimed to examine the clinical, ethical, and theoretical implications of integrating GenAI into the therapeutic space through a proof-of-concept (POC) of AI-driven externalization techniques, while emphasizing the essential role of the human therapist.MethodsTo this end, we developed two customized GPTs agents: VIVI (visual externalization), which uses DALL-E 3 to create images reflecting patients' internal experiences (e.g., depression or hope), and DIVI (dialogic role-play-based externalization), which simulates conversations with aspects of patients' internal content. These tools were implemented and evaluated through a clinical case study under professional psychological guidance.ResultsThe integration of VIVI and DIVI demonstrated that GenAI can serve as an “artificial third”, creating a Winnicottian playful space that enhances, rather than supplants, the dyadic therapist-patient relationship. The tools successfully externalized complex internal dynamics, offering new therapeutic avenues, while also revealing challenges such as empathic failures and cultural biases.DiscussionThese findings highlight both the promise and the ethical complexities of AI-enhanced therapy, including concerns about data security, representation accuracy, and the balance of clinical authority. To address these challenges, we propose the SAFE-AI protocol, offering clinicians structured guidelines for responsible AI integration in therapy. Future research should systematically evaluate the generalizability, efficacy, and ethical implications of these tools across diverse populations and therapeutic contexts.