bluuebunny/crossref_metadata_2025_split huggingface dataset:
Haemoadsorption in infective endocarditis: a systematic review
Authors: Thielmann Matthias , Dohle Daniel-Sebastian , Czerny Martin , Bonaros Nikolaos , Wendt Daniel , Folliguet Thierry , Baufreton Christophe , Lebreton Guillaume 
Published: February 2024

AbstractInfective endocarditis surgical patients suffer from high rates of severe complications such as systemic inflammatory response, septic shock, and multi-organ failure leading to high mortality. Systemic inflammatory response based on cytokines as messengers plays an important role in these patients. The concept of intraoperative haemoadsorption has been proposed to remove such elevated cytokines in patients undergoing cardiac surgery for infective endocarditis. Haemoadsorption offers the possibility to stabilise haemodynamics, reduce sepsis-related mortality, and protect organ function. However, until now, there has been no general opinion and consensus regarding the clinical effectiveness of adjunctive intraoperative haemoadsorption in infective endocarditis. Therefore, we reviewed the current literature evaluating haemoadsorption in infective endocarditis patients undergoing cardiac surgery. The review was registered at PROSPERO (CRD42023457632).
“How Long Are You Gonna Stay?” Implications of Residents’ Perceptions of Refugees’ Occupational Future Time Perspective in Receiving Countries
Authors: Niemann Lena , Naudascher Hanna , Kuyumcu Umay , Hertel Guido 
Published: February 2024

AbstractOccupational work is a cornerstone for refugees’ integration in a receiving country, and residents’ perceptions of refugees is a key factor in this process. As compared to migrants in general, refugee migrants have been forced to leave their home country, which should have multiple implications for their integration in receiving countries. In the current study, we investigated whether residents’ perception of migration forcedness affects their expectations about migrants’ occupational future time perspectives (OFTP) in the receiving country, which in turn should correspond to expectations about migrants’ occupational integration efforts. We tested our hypotheses in a preregistered online experiment with N = 190 working adults in Germany (71% women; age: M = 50.26, SD = 10.78). The results confirmed the hypothesized negative relation between perceived migration forcedness and expected OFTP, the hypothesized positive relation between expected OFTP and expected occupational integration efforts, and the hypothesized mediation mechanism of expected OFTP. Overall, our results demonstrate that residents’ perception of migration forcedness and related OFTP are relevant processes that affect the integration of migrants into the labor market of receiving countries.
Percutaneous Alginate Hydrogel Endomyocardial Injection with a Novel Dedicated Catheter Delivery System: An Animal Feasibility Study
Authors: Wang Bo , Gao Chao , Lim Scott , Wang Rutao , Zhu Cun-jun , Onuma Yoshinobu , Wang Yunbing , Gao Runlin , Serruys Patrick W. J. C. , Lee Randall J. , Tao Ling 
Published: February 2024

AbstractThe objective of this preclinical study was to evaluate the feasibility and safety of transcatheter endocardial alginate hydrogel injection (TEAi) in a large animal model, utilizing the high-stiffness XDROP® alginate hydrogel in combination with the dedicated EndoWings® catheter-based system. All swine (n = 9) successfully underwent TEAi without complications. Acute results from a subset of animals (n = 5) demonstrated the ability of the catheter to access a wide range of endomyocardial areas and achieve consecutive circumferential hydrogel distribution patterns within the mid-left ventricular wall. Histological examinations at 6 months (n = 4) demonstrated that the XDROP® remained localized within the cardiac tissue. In addition, serial echocardiographic imaging showed that XDROP® had no adverse impacts on LV systolic and diastolic functions. In conclusion, this innovative combination technology has the potential to overcome the translational barriers related to alginate hydrogel delivery to the myocardium.
Graphical abstract
From emissions to resources: mitigating the critical raw material supply chain vulnerability of renewable energy technologies
Authors: Mertens Jan , Dewulf Jo , Breyer Christian , Belmans Ronnie , Gendron Corinne , Geoffron Patrice , Goossens Luc , Fischer Carolyn , Du Fornel Elodie , Hayhoe Katharine , Hirose Katsu , Le Cadre-Loret Elodie , Lester Richard , Maigné Fanny , Maitournam Habibou , de Miranda Paulo Emilio Valadão , Verwee Peter , Sala Olivier , Webber Michael , Debackere Koenraad 
Published: February 2024

AbstractThe massive deployment of clean energy technologies plays a vital role in the strategy to attain carbon neutrality by 2050 and allow subsequent negative CO2 emissions in order to achieve our climate goals. An emerging challenge, known as ‘From Emissions to Resources,’ highlights the significant increase in demand for critical raw materials (CRMs) in clean energy technologies. Despite the presence of ample geological reserves, ensuring sustainable access to these materials is crucial for the successful transition to clean energy, taking into account the environmental and social impacts. The commentary centers on four renewable energy technologies namely solar photovoltaics, wind turbines, Li-ion batteries, and water electrolysers. Four pathways for mitigation are quantitatively examined to assess their potential in reducing the vulnerability of the CRM supply chain for these four clean energy technologies: (i) Enhancing material efficiency, (ii) employing substitutivity strategies, (iii) exploring recycling prospects, and (iv) promoting relocalisation initiatives. It is important to note that no single mitigation lever can completely eliminate the risk of CRM supply, rather the accelerated adoption of all four levers is necessary to minimize the CRM supply risk to its absolute minimum. Hence, the study underscores the significance of increased research, innovation, and regulatory initiatives, along with raising social awareness, in effectively addressing the challenges faced by the CRM supply chain and contributing to a sustainable energy transition.
A Systematic Review of the Effects of Multi-purpose Forest Management Practices on the Breeding Success of Forest Birds
Authors: Cordeiro Pereira João M. , Mikusiński Grzegorz , Storch Ilse 
Published: February 2024

Abstract
Purpose of Review
We aimed to summarize the evidence linking multi-purpose forest management (MPF) to bird nesting and fledging success in temperate and boreal forests and to identify outstanding research gaps. Forest birds are in decline worldwide, but an ongoing move from production-oriented management towards MPF, integrating biodiversity conservation with other uses, may help counteracting these trends. The effects of MPF on bird diversity and abundance are well-studied, but less is known about effects on bird demographics.

Recent Findings
We retrieved 101 studies, reporting 342 outcomes of MPF for nesting and fledging success. Due to the heterogeneity of the studies, we opted for a systematic mapping approach, accompanied by vote-counting and narrative review. Studies covered 11 types of MPF and 151 bird species. The most frequently studied interventions were overstorey retention and prescribed burning, but research was markedly biased towards temperate North America. Most outcomes (79.5%) were non-significant, and studies often found that breeding success was driven by ecological processes at both broader and finer scales than management interventions. Thus, managing for breeding success likely requires complementary management actions at various scales. Nonetheless, significant positive and negative outcomes of MPF were also found, inclusively affecting species of conservation concern, highlighting the variability and context-dependence of MPF effects.

Summary
In order to foster effectiveness of MPF for forest birds, future research should focus on a set of under-researched interventions and regions, as well as on ecosystem-wide experiments accounting for functional links between bird abundance, demographics, nest predation, and food supply.
Turbulence modelling in neutron star merger simulations
Authors: Radice David , Hawke Ian 
Published: February 2024

AbstractObservations of neutron star mergers have the potential to unveil detailed physics of matter and gravity in regimes inaccessible by other experiments. Quantitative comparisons to theory and parameter estimation require nonlinear numerical simulations. However, the detailed physics of energy and momentum transfer between different scales, and the formation and interaction of small scale structures, which can be probed by detectors, are not captured by current simulations. This is where turbulence enters neutron star modelling. This review will outline the theory and current status of turbulence modelling for relativistic neutron star merger simulations.
Does the Australian school system and curriculum support young people to become active and informed citizens?
Authors: Doecke Esther , Huo Shuyan 
Published: February 2024

AbstractDoes the Australian school system and curriculum support students to become active and informed’ members of the community, which is a key aspiration of the Australian school system set out in the Alice Springs (Mparntwe) Education Declaration? We address this question by drawing on the Australian National Assessment Program (NAP) civics and citizenship data. The NAP data measures Year 6 and Year 10 students’ awareness of civics and citizenship content as well as their participation in civics and citizenship-related activities at school. The data suggests that students are being informed about social, political and economic issues, but there are differences between students with respect to their active engagement in civics and citizenship related activities at school deriving from their parents’ educational level and age group. But the curriculum is also at issue here. The prescriptive Australian Curriculum framework has a heavy emphasis on academic learning particularly during the secondary years, which sidelines active participation in civics and citizenship education. Furthermore, the Australian Curriculum constrains teachers in their ability to enact a truly negotiated curriculum that is meaningful to students and may enhance their sense of being part of the community and citizens of a democratic society.
Hypernorm on hypervector spaces over a hyperfield
Authors: Pallavi P. , Kuncham S. P. , Tapatee S. , Vadiraja B. , Harikrishnan P. K. 
Published: February 2024

AbstractHypernorm is a generalization of the notion of a norm on a vector space over a field. In this paper, we consider a hypervector space $$(\mathbb {V}, +)$$

(
V
,
+
)

over a hyperfield, where $$+$$
+
is a hyperoperation, and prove that the hypernorm is continuous. We show that the natural linear transformation from $$\mathbb {V}$$
V
to $$\dfrac{\mathbb {V}}{Z}$$

V
Z

is continuous and open for all closed subhyperspaces Z of $$\mathbb {V}$$
V
. We prove $$BL(\mathbb {V},\mathbb {W}),$$

B
L
(
V
,
W
)
,

the set of all bounded linear transformations from $$\mathbb {V}$$
V
to $$\mathbb {W}$$
W
is a hyper-Banach space whenever $$\mathbb {W}$$
W
is complete. Furthermore, we obtain that in a hyper-Banach space $$\mathbb {V}$$
V
if $$\lbrace \mu _n \rbrace$$

{

μ
n

}

is a sequence of continuous linear transformations with $$\lbrace /\mu _n(u)/ \rbrace$$

{
/

μ
n

(
u
)

/
}

is bounded for every $$u \in \mathbb {V},$$

u
∈
V
,

then $$\lbrace \Vert \mu _n\Vert \rbrace$$

{
‖

μ
n

‖
}

is bounded. In the sequel, we prove several properties of hypernorm and linear transformations on hypernormed spaces.
Temperature Control and Data Exchange in Food Supply Chains: Current Situation and the Applicability of a Digitalized System of Time–Temperature-Indicators to Optimize Temperature Monitoring in Different Cold Chains
Authors: Waldhans Claudia , Albrecht Antonia , Ibald Rolf , Wollenweber Dirk , Sy Su-Jen , Kreyenschmidt Judith 
Published: February 2024

AbstractThe current situation of temperature monitoring in perishable food supply chains and the optimization of temperature control was studied by combining two approaches. First, a survey among German companies (production, processing, logistics, wholesale, retail) was conducted to analyze the current temperature monitoring and data management conditions as well as the use of novel monitoring systems, such as Time–Temperature-Indicators (TTIs). Second, the temperature conditions in three different supply chains (B2C for raw pork sausage, B2B for fish, B2C e-commerce for mixed products) were investigated to analyze the applicability of TTIs with an app-based read-out system to identify weak points and to optimize cold chain management under practical conditions. The results of the survey showed that mainly static conditions are tested along the supply chain. Thus, the actors rely mostly on visual inspection or best-before date labeling while TTIs are not widely used. Currently, temperature data are barely exchanged by stakeholders. In the B2C chain, mean temperatures on different pallet levels were comparable, also reflected by TTIs and the app-based read-out system, respectively. In the B2B chain, temperature interruptions during the unloading process were detected, revealing main challenges in perishable supply chains. Temperature monitoring by TTIs on a box level was possible by positioning the label close to the product. Results in the e-commerce sector showed heterogeneous conditions in different boxes depending on initial product temperatures and loading. TTIs and the app-based read-out system showed reliable results based on different temperature scenarios, when TTIs are positioned close to the most sensitive product.
Reduced sulfur compounds and carboxylic acid groups in dissolved PFRs of iron-biochar enhance Cr(VI) reduction in anaerobic conditions
Authors: Hu Shujie , Liu Chengshuai , Bu Hongling , Chen Manjia , Tang Jiao , Jiang Bin , Ran Yong 
Published: February 2024

AbstractIn addition to the adsorption and immobilization capacities of iron-modified biochars, these materials produce persistent free radicals (PFRs) that can carry out metal [i.e., Cr(VI)] redox transformations, but the primary forms and active species of PFRs involved are not well understood. Here, we investigated the key species of PFRs of α-Fe2O3-modified biochar (MBC) and their influence on Cr(VI) reduction under anaerobic conditions simulating paddy soil environments. MBC produced bulk phenoxyl PFRs that promoted Cr(VI) reduction due to the catalytic effect of the transition metal Fe. In addition, MBC was more efficient in reducing Cr(VI) under anaerobic conditions than under aerobic conditions due to the more active and accessible dissolved PFRs present in the dissolved organic matter (DOM). The electron transfer capacity of DOM was demonstrated by excitation-emission matrix (EEM) spectrophotometry combined with parallel factor analysis, which showed that the protein-like and humic-like components of DOM were involved in Cr(VI) reduction. Furthermore, Fourier transform ion cyclotron resonance mass spectrometry (FTICR-MS) analysis indicated that reduced-S compounds (O/S < 4) and carboxylic acid (–COO) groups in the unsaturated aliphatic and lignin-like compounds are potentially the main active species accelerating Cr(VI) reduction under anaerobic conditions. Our results provide new insights into the role of dissolved PFRs from iron-modified biochar in promoting Cr(VI) reduction under anaerobic conditions such as flooded soils.
Graphical Abstract
A new graph theoretic analytical method for nonlinear distributed order fractional ordinary differential equations by clique polynomial of cocktail party graph
Authors: Nirmala A. N. , Kumbinarasaiah S. 
Published: February 2024

AbstractIn this paper, we presented a new analytical method for one of the rapidly emerging branches of fractional calculus, the distributed order fractional differential equations (DFDE). Due to its significant applications in modeling complex physical systems, researchers have shown profound interest in developing various analytical and numerical methods to study DFDEs. With this motivation, we proposed an easy computational technique with the help of graph theoretic polynomials from algebraic graph theory for nonlinear distributed order fractional ordinary differential equations (NDFODE). In the method, we used clique polynomials of the cocktail party graph as an approximation solution. With operational integration and fractional differentiation in the Caputo sense, the NDFODEs transformed into a system of algebraic equations and then solved by Newton–Raphson's method to determine the unknowns in the Clique polynomial approximation. The proficiency of the proposed Clique polynomial collocation method (CCM) is illustrated with four numerical examples. The convergence and error analysis are discussed in tabular and graphical depictions by comparing the CCM results with the results of existing numerical methods.
Spectrophotometric quantification of amitriptyline hydrochloride in pharmaceutical tablets: method development and validation
Authors: Abdulrahman Sameer A. M. , Al-khawlani Abdullah R. 
Published: February 2024

AbstractThe development and validation of two uncomplicated, selective, and non-extraction-based visible spectrophotometric methods was carried out for the quantification of a tricyclic antidepressant amitriptyline hydrochloride as pharmaceutical tablets as well as in its pure form. The methods rely on the formation of ion pair complexes between amitriptyline base and two acidic dyes, bromothymol blue and bromocresol purple, which were subsequently measured at 410 and 400 nm, respectively. The developed methods included numerous reaction variables that were examined and improved. Beer's law is applicable under optimal conditions for the bromothymol blue and bromocresol purple methods, respectively, over concentrations from 0.5 to 12.5 μg mL−1 and from 0.5 to 10.0 μg mL−1 amitriptyline hydrochloride. The computed values of molar absorptivity were 1.79 × 104 and 2.32 × 104 L.mol−1.cm−1 for bromothymol blue and bromocresol purple methods, respectively, with Sandell’s sensitivity values of 0.0155 and 0.0119 μg cm−2. Both detection limits and quantification limits were computed and determined to be 0.55 and 1.67 μg mL−1 for bromothymol blue method, and 0.49 and 1.49 μg mL−1 for bromocresol purple method, respectively. The developed methods were successfully applied to estimate the concentration of amitriptyline hydrochloride in bulk form and commercial pills. Therefore, these methods demonstrate promising potential for testing this drug in labs for quality control.
Graphical abstract
Spectrophotometric quantification of amitriptyline hydrochloride in pharmaceutical tablets: method development and validation
The role of the type VI secretion system in the stress resistance of plant-associated bacteria
Authors: Yin Rui , Cheng Juanli , Lin Jinshui 
Published: February 2024

AbstractThe type VI secretion system (T6SS) is a powerful bacterial molecular weapon that can inject effector proteins into prokaryotic or eukaryotic cells, thereby participating in the competition between bacteria and improving bacterial environmental adaptability. Although most current studies of the T6SS have focused on animal bacteria, this system is also significant for the adaptation of plant-associated bacteria. This paper briefly introduces the structure and biological functions of the T6SS. We summarize the role of plant-associated bacterial T6SS in adaptability to host plants and the external environment, including resistance to biotic stresses such as host defenses and competition from other bacteria. We review the role of the T6SS in response to abiotic factors such as acid stress, oxidation stress, and osmotic stress. This review provides an important reference for exploring the functions of the T6SS in plant-associated bacteria. In addition, characterizing these anti-stress functions of the T6SS may provide new pathways toward eliminating plant pathogens and controlling agricultural losses.
Spatial Variation in Excess Mortality Across Europe: A Cross-Sectional Study of 561 Regions in 21 Countries
Authors: Bonnet Florian , Grigoriev Pavel , Sauerberg Markus , Alliger Ina , Mühlichen Michael , Camarda Carlo-Giovanni 
Published: February 2024

Abstract
Objective
To measure the burden of the COVID-19 pandemic in 2020 at the subnational level by estimating excess mortality, defined as the increase in all-cause mortality relative to an expected baseline mortality level.

Methods
Statistical and demographic analyses of regional all-cause mortality data provided by the vital statistics systems of 21 European countries for 561 regions in Central and Western Europe. Life expectancy losses at ages 0 and 60 for males and females were estimated.

Results
We found evidence of a loss in life expectancy in 391 regions, whilst only three regions exhibit notable gains in life expectancy in 2020. For 12 regions, losses of life expectancy amounted to more than 2 years and three regions showed losses greater than 3 years. We highlight geographical clusters of high mortality in Northern Italy, Spain and Poland, whilst clusters of low mortality were found in Western France, Germany/Denmark and Norway/Sweden.

Conclusions
Regional differences of loss of life expectancy are impressive, ranging from a loss of more than 4 years to a gain of 8 months. These findings provide a strong rationale for regional analysis, as national estimates hide significant regional disparities.
Impacts of Inflammatory Cytokines Variants on Systemic Inflammatory Profile and COVID-19 Severity
Authors: Deng XueJun , Tang Kai , Wang Zhiqiang , He Suyu , Luo Zhi 
Published: February 2024

Abstract
Background
Cytokine storm is known to impact the prognosis of coronavirus disease 2019 (COVID-19), since pro-inflammatory cytokine variants are associated with cytokine storm. It is tempting to speculate that pro-inflammatory cytokines variants may impact COVID-19 outcomes by modulating cytokine storm. Here, we verified this hypothesis via a comprehensive analysis.

Methods
PubMed, Cochrane Library, Central, CINAHL, and ClinicalTrials.gov were searched until December 15, 2023. Case–control or cohort studies that investigated the impacts of rs1800795 or rs1800629 on COVID-19 susceptibility, severity, mortality, IL-6, TNF-α, or CRP levels were included after an anonymous review by two independent reviewers and consultations of disagreement by a third independent reviewer.

Results
47 studies (8305 COVID-19 individuals and 17,846 non-COVID-19 individuals) were analyzed. The rs1800629 A allele (adenine at the −308 position of the promoter was encoded by the A allele) was associated with higher levels of tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP). In contrast, the rs1800795 C allele (cytosine at the −174 position of the promoter was encoded by the C allele) was linked to higher levels of interleukin-6 (IL-6) and CRP. In addition, the A allele of rs1800629 increased the severity and mortality of COVID-19. However, the C allele of rs1800795 only increased COVID-19 susceptibility.

Conclusions
rs1800629 and rs1800795 variants of pro-inflammatory cytokines have significant impacts on systemic inflammatory profile and COVID-19 clinical outcomes. rs1800629 may serve as a genetic marker for severe COVID-19.