bluuebunny/crossref_metadata_2025_split huggingface dataset:
Improvement of agrotechnical conditions of growing paulownia in the Forest Steppe of Ukraine
Authors: Humentyk M. Ya. , Bordus O. Yu. 
Published: November 2023

Purpose. The purpose of the study was to improve the agrotechnical conditions for growing paulownia and its artificially bred variety Clone in vitro 112 in the Forest Steppe zone of Ukraine.
Methods. Field, laboratory, visual, measuring and weighing, mathematical and statistical.
Results. The article presents the results of research on the improvement of agrotechnical growing conditions and establishment of indicators of growth and development of paulownia plants in the Central Forest Steppe of Ukraine. The methods of planting, the optimal width between the rows, and the options for caring for the plantation of plants have been substantiated. It was established that in the first year of vegetation, the root system of paulownia plants is intensively formed. In order to obtain high-quality wood, after the first year of vegetation, it is necessary to make a technical cut at a height of 2–3 cm from the surface of the ground and remove young newly formed shoots (tillers). The highest trunk height of Clone in vitro 112 was formed in the first and second year of vegetation and reached 5–6 m. The optimal planting density is 625 plants per hectare. Conclusions. It was established that paulownia seedlings in vitro should undergo adaptation to the temperature conditions of the growing area for two to three weeks before planting in open ground.
Winter wheat seed treatment
Authors: Polishchuk V. V. , Konovalov D. V. 
Published: November 2023

Problem statement. The article presents the results of research on the peculiarities of post-harvest and pre-sowing winter wheat seed treatment using a modern technological line.
Methods. Laboratory, measuring and weighing, mathematical and statistical.
Results. Pre-sowing seed treatment is carried out in three stages: primary cleaning of small and large impurities and small seeds of the main crop, pre-sowing preparation — calibration of seeds by size, aerodynamic properties and specific weight in order to improve seed quality and final treatment with insecticides, fungicides and other substances for protection seddlings from pests and diseases. The technological line for the preparation of seeds of agricultural crops, which was installed at the Research Agricultural Production Institute of the Institute of Plant Physiology and Genetics of the National Academy of Sciences of Ukraine, provided a yield of conditioned winter wheat seeds of 84–92.4%, depending on varietal characteristics. Seed yield differed by variety. The highest yield was obtained by pre-sowing seed treatment of the ‘Darynka Kyivska’ variety — 92.4%, and the lowest with Horodnytsia’ and ‘Novosmuhlianka’ varieties — 84.0%. Conclusions. Pre-sowing seed treatment on the technological line with a small waste, which was an average of 13.3% for varieties, ensured obtaining of five batches of seeds, which in terms of germination rate exceeded the requirements of the current standard by 4%, as well as an increase in the 1000 kernel weight to 44.0 grams.
Yield structure of safflower under the influence of row width and seeding rate
Authors: Kalenska S. M. , Hordyna N. Yu. 
Published: November 2023

Purpose. To establish the peculiarities of the productivity formation of different safflower varieties under the influence row width and seeding rate in the Right Bank Forest Steppe of Ukraine.
Methods. The research was carried out in typical chernozem at the agronomic research station of the National University of Life and Environmental Sciences of Ukraine in 2021–2022 as a three-factor field experiment. Factor A (variety): ‘Dobrynia’ and ‘Soniachnyi’; factor B (row width): 19, 38, and 57 cm; factor C (seeding rate): 100, 200 and 300 thousand seeds/ha.
Results. In the experiment, plant height of the variety ‘Dobrynia’ varied between 100.7 and 114.3 cm and 'Soniachnyi' between 93.5 and 108.9 cm. The number of heads per plant was 15.5–20.6 and 7.0–19.8, 1000-kernel weight 40.6–45.4 g and 38.8–47.7 g, respectively; number of seeds per plant 148–513 and 145–508, seed weight per plant 6.9–22.5 and 6.9–22.7 g/plant. As for plant height, in both varieties, its indicators increased with an increase in the seeding rate for all variants of row widths, reaching maximum values with a row width of 19 cm and a seeding rate of 300,000 seeds/ha. The rest of the biometric parameters, on the contrary, showed a clear regularity to decrease along with an increase in the seeding rate. At the same time, the highest number of heads and the seed weight per plant were in variants with a row width of 38 cm; the highest 1000- kernel weight was for the row width of 57 cm; the highest number of seeds per plant was for the row width of 19 cm. The biological yield of seeds in the experiment ranged from 1.25 to 2.55 t/ha in ‘Dobrynia’ and from 1.21 to 2.52 t/ha in ‘Soniachnyi'. In both varieties, biological yield increased with an increase in the seeding rate, reaching maximum values at a row width of 38 cm.
Conclusions. Both studied varieties demonstrated the highest yield for the row width of 38 cm and a seeding rate of 300,000 seeds/ha: 2.55 t/ha ‘Dobrynia’ and 2.52 t/ha ‘Soniachnyi’. Despite the fact that these safflower varieties are recommended for the cultivation in the southern regions, they are quite adaptive for the cultivation in the north of Ukraine as well, taking into account the gradual increase in average annual temperatures and high soil fertility.
Role of Innovation Management Practices in Enhancing Firm Agility and Adaptability during Times of Crisis in Turkey
Authors: Azra Aydin 
Published: November 2023

Purpose: The study sought to investigate the role of innovation management practices in enhancing firm agility and adaptability during times of crisis in Turkey.
Materials and Methods: The study adopted a desktop methodology. Desk research refers to secondary data or that which can be collected without fieldwork. Desk research is basically involved in collecting data from existing resources hence it is often considered a low cost technique as compared to field research, as the main cost is involved in executive’s time, telephone charges and directories. Thus, the study relied on already published studies, reports and statistics. This secondary data was easily accessed through the online journals and library
Findings: The study found that Turkish firms embracing innovation management practices exhibited enhanced agility and adaptability during crises. These practices included nurturing an innovative culture, investing in research and development, and embracing digital solutions. Leadership commitment and external collaborations were identified as crucial enablers. Additionally, the research underscored the importance of tailoring strategies to Turkey's specific context to effectively bolster firm resilience during challenging times.
Unique Contribution to Theory, Practice and Policy: The study recommends Turkish firms should formulate agile innovation strategies that emphasize flexibility and rapid response to changing market conditions. This involves regularly assessing customer needs, market trends, and emerging technologies. By continuously adapting their innovation strategies, firms can remain responsive and agile during crises. This recommendation contributes to theory by emphasizing the integration of agility principles into innovation management frameworks, highlighting the need for dynamic and iterative approaches. Encourage cross-functional collaboration within organizations to facilitate innovation.
INTELIGÊNCIA ARTIFICIAL E SEUS IMPACTOS NA EDUCAÇÃO: UMA REVISÃO SISTEMÁTICA
Authors: Ramos da Silva Keila , Sergio de Oliveira Barbosa Luiz , Lira Botelho Wendrews , Mateus Barbosa Pinheiro João , Dos Santos Peixoto Isabelle , Vitoria Coimbra Borges de Menezes Itala 
Published: November 2023

Este estudo analisa o impacto da inteligência artificial (IA) na educação, destacando a personalização da aprendizagem como um benefício. O objetivo deste artigo é analisar de forma abrangente o papel da IA na transformação do ensino e da aprendizagem. A metodologia empregada é a revisão sistemática da literatura, conduzida de maneira formal e estruturada. Foram realizadas pesquisas bibliográficas em plataformas científicas de renome, com critérios de inclusão bem definidos. Foram selecionados 20 artigos que demonstraram consistência e alinhamento com os objetivos da revisão. A abordagem qualitativa, embasada em evidências da literatura científica, permitiu uma compreensão aprofundada do tema. Os resultados revelam que a Inteligência artificial na educação tem um impacto substancial. A personalização da aprendizagem é destacada como um dos principais avanços, adaptando o ensino às necessidades individuais dos alunos. No entanto, são discutidas preocupações éticas, como a precisão das respostas geradas pela IA e a proteção da privacidade dos dados dos alunos. A integração eficaz entre a IA e a supervisão humana é enfatizada como crucial para garantir uma educação de alta qualidade. Em conclusão, a pesquisa aponta para um cenário promissor na educação impulsionado pela IA. A personalização da aprendizagem é destacada como um benefício significativo. No entanto, são ressaltadas preocupações éticas que devem ser cuidadosamente consideradas. A colaboração entre a IA e a orientação humana é vista como a chave para maximizar os benefícios dessa revolução educacional em andamento.
An Assessment of the Current Trends of Antibiotic Resistance of Salmonella Typhi Against 1st Line Antimicrobial Agents in Metropolitan City of Karachi
Authors: Maria Haider  , Sobia Jamil  , Sakina Fatima  , Aylia Mazhar  , Hussain Abidi  
Published: November 2023

Objectives: To assess current trends of antibiotic resistance against S. typhi in Pakistani population.
Methodology: This was a cross-sectional, observational descriptive research conducted in various diagnostic facilities in Karachi-Pakistan from January 2019 to November 2020. A data of 1223 patients, who were reported positive for typhoid fever, was collected from various diagnostic facilities with in the area. Clinical isolates were examined for culture sensitivity by using BACTEC™ and Versa TREK™. Isolates of the Salmonella typhi and para typhi were recovered from blood of the patients. The collected data was analyzed using SPSS version 22.0.
Results: Among all isolates, 92.7% (n=1134) isolates were identified as S. typhi and the remaining 7.3% (n=89) as S. paratyphi. Study population suffering from typhoid fever were 58.5% (n=716) male trailed by 41.5% (n=507) female. Similarly, among 1223 clinical isolates, 14.2% (n=174) were non-resistant, 5.4% (n=66) were multi-drug resistant (MDR), 56.4% (n=690) were extensive drug resistant (XDR), 12.7% (n=155) were moving towards multi-drug resistant species trend and 5.7% (n=70) were heading towards XDR. A further 5.6% (n=68) were moving towards ESBL positive typhoid fever. Moreover, 49.1% of the S. typhi isolates were found to be resistant to all the first line antibiotics agents (ampicillin, chloramphenicol and co-trimoxazole) with only 15.2% found to be sensitive to all first line antibiotics drugs.
Conclusion: Strains of Salmonella typhi in Karachi are resistant to most of the drugs recommended by local infectious disease society for treatment of typhoid. This is alarming for healthcare policy makers because of lack of newer drugs discovered for treatment of typhoid fever and pathogens isolated for this highly infectious disease being resistant to most of the recommended anti-microbial agents.
Keywords: Typhoid fever, Drug resistance, XDR, Salmonella typhi
Mentalization, emotional dysregulation and attachment to alternative attachment figures in retrospectively defined earned secure adults
Authors: Jańczak Monika Olga 
Published: November 2023

BackgroundResearchers have tried to identify mechanisms through which an individual overcomes negative life experiences, proposing earning security as one of them. Retrospectively defined earned secures are recognized as individuals exhibiting secure attachments to their parents while evaluating the quality of their childhood care as low. This study aimed to examine at-tachment, mentalization, and emotional dysregulation in this group. We hypothesized that earned secures will report better mentalizing, lower emotion dysregulation, and more secure attachment to figures other than parents than insecure individuals.Participants and procedureA female adult sample (N = 272) completed the Experiences in Close Relationships–Relationship Structures questionnaire, Parental Bonding Instrument, Difficulties in Emotion Regulation Scale, and Mental State Task. The time devoted to psycho-therapy and demographics were also controlled as contextual variables.ResultsWe identified an ‘earned secure’ group (14% of the sample), exhibiting secure attachment to mothers in adulthood despite reported inadequate care during childhood, along with the continuously secure, insecure, and ‘lost secure’ groups. People from the earned secure and secure groups reported better emotional regulation and some aspects of mentalization than those in the insecure and lost secure groups. They equally frequently reported the presence of an adult other than parents who were important to them in childhood, but the attachment to them was more secure. We did not find evidence of differ-ences between the groups in the duration of psychotherapy.ConclusionsSecure attachment to alternative attachment figures, along with some mentalization and emotional regulation aspects, may be considered significant factors for earning security.
„Künftig Teil eines nachhaltigen Pflanzenbaus“
Authors: Schaal René 
Published: November 2023

Frankfurt a.M. Im Interview mit der agrarzeitung spricht Jörn-Fried Johannsen vom Industrieverband Agrar (IVA) über das Marktpotenzial von Biostimulanzien – und die Erwartungshaltung der Landwirte.
A case study on the effectiveness of Attai vedal (leech therapy) for the treatment of Karappan (eczema)
Authors: Logisha M. SriSakthi , Nivetha G. , Mustafa M. Mohamed , Siddiq Ali T. R. , Muthukumar N. J. , Mahalakshmi M. V. 
Published: November 2023

There are more than 3000 known common skin diseases. Eczema, generally referred to as karappan, is a prevailing dermatological condition often seen in clinical settings. It is not an immediately life-threatening disease; it is a chronic disease that has a physiological and social impact on a patient’s life. The skin lesion is manifested externally and visible to all. So, the patient feels detested and has depression. The disease may affect any age, but it is common in school-going age and 1-3 percent of adults. It is characterized by itching followed by redness, erythema, and papules. The papules may turn to vesicles. The condition known as karappan in the Siddha system of medicine is considered equivalent due to the presence of analogous signs and symptoms. Management of eczema involves emollients, steroids, and topical application therapy given in other systems. It will give temporary remedies even after use, relapse, recurrence and other complications are common. Hence, there is a need for alternative drugs and therapy that has a good efficacy in this debilitating disorder, which is possible through the Siddha system of medicine. Leech therapy (attai vidal) our siddhars have given importance to bloodletting therapy and concede leech is the most unique and effective method of bloodletting even in an infected wound, skin disease, and abscesses. The present case was carried out in the OPD of the department of Sirappu Maruthuvam, Government Siddha Medical College, Chennai, Tamil Nadu in India. The course of treatment has shown significant improvement in terms of alleviating all of the symptoms and improving the patient's easy score.
A study on placental expression of neuronal markers in intrauterine growth restriction
Authors: Reddy Pulluru Upendhar , Chelli Sudhakara Babu , Reddy Muchinthala Venkateshwar , V. Sthevaan , Charitha Sai , Priya Reddy Sai , Sumathy Govindarajan 
Published: November 2023

Introduction and Aim: The restriction of intrauterine growth (IUGR) has a 20% recurrence rate and is one of the leading causes of postnatal illness and death. The diagnosis of intrauterine retardation refers to the infant's increased risk of neurological issues over an extended period, neonatal morbidity, and mortality, and in utero death.

Materials and Methods: One hundred placenta samples were collected and divided into cases and controls. Clearance from the ethics committee was taken from the institute prior to the commencement of this study. Exclusion criteria include the patients with multiple pregnancies, unknown gestational age, gestational diabetes, and HIV. The inclusion criteria are the singleton pregnancy, normal and cesarean section, maternal age between 18-35 years and GA between 34 – 41 weeks. Standard immunohistochemistry protocols were followed for the study and glial fibrillary acidic protein (GFAP), neuron specific enolase (NSE) markers were used as neuronal markers.

Results: Strong immunoreactivity of glial fibrillary acidic protein and neuron specific enolase was observed in fetal growth restriction placenta indicating perinatal brain damage of neonate.

Conclusion: In our study we observed strong positive immunoreactivity of GFAP and NSE in IUGR only. This study suggests that these markers are used to predict brain damage in IUGR neonates.
Investigating the molecular mechanisms of Ashwagandha phytocompounds in epilepsy through differential gene expression and pathway analysis
Authors: Govinda Srinivasan Srivarshini , Dinesh Susha , Sharma Sameer , Sunkadakatte Venugopal Bhavana , Lucas A. Martin , Sosalagere Manjegowda Dinesh 
Published: November 2023

Introduction and Aim: Withania somnifera (Ashwagandha) is a traditional Indian herb used in Ayurveda and Unani medicine, particularly in anti-inflammatory, anti-cancer, anti-stress, antioxidant, immune-boosting, and rejuvenating effects. Epilepsy is a severe neuropsychological condition that occurs sporadically and has a long-term effect on the electrical signals that travel between brain cells. The disorder is characterized by recurrent seizures that are brought on by a sudden increase in brain electrical activity. This is the outcome of abnormal neuronal discharges or coordinated neuronal hyperexcitability. The study’s main objective is to find out the therapeutic phytocompound in treating Epileptic disorder.

Materials and Methods: This study investigated the potential use of phytochemicals from the Ashwagandha plant as epileptic seizure treatments that target key genes strongly associated with the disease. To forecast the binding affinity between the phytochemicals and the receptors, molecular docking simulations (PyRx) were used for the virtual screening.

Results: The preliminary screening of the twenty-two phytocompounds from Withania somnifera was based on their affinity for epilepsy. The results showed that withasomnine exhibited great binding affinity to the receptors, indicating their potential as targeted epileptic seizure therapeutics. The ligands revealed stronger binding with the epilepsy targets, and the binding score less than -7 kcal/mol was taken into consideration for further exploration. This research lays the groundwork for upcoming in-vitro and in-vivo studies to confirm the effectiveness of these phytochemicals as cancer therapies.

Conclusion: The results suggest that withasomnine derivatives from Withania somnifera could be a promising source of epilepsy therapies.
Evaluation of the foundation block of first year MBBS curriculum in a medical college
Authors: S. Mantur Venkappa , Reddy C. Sudarshan , Kumar Arun , Kowale Arun 
Published: November 2023

Introduction and Aim: The National Medical Council of India (NMC) has updated the undergraduate medical curriculum by establishing "competency based medical education," which focuses on a one-month foundation course. This time is thought to be crucial for students to adjust to their new college surroundings. The purpose of this study was to assess the initial one-month foundation course from the perspectives of students.

Materials and Methods: A total of 150 first year MBBS students joining the college in the academic year 2020-21 were included in the study. Therefore, all students’ means universal samples were included in the study. The core curriculum was meticulously organised and carried out in accordance with the National Medical Council of India's recommendations. Students provided feedback using a five-point Likert scale. Before the final study, we conducted a pilot study for assessment of the reliability of the scale by taking convenient samples and reliability coefficient was found to be 0.8769. Overall recommendations were solicited, and the outcomes were analysed using feedback from students. It calculated the percentage of students who responded. The data were analysed by using statistical software i.e., SPSS version 20.00 with simple frequency and percentages.

Results: The percentages of students who agreed and strongly agreed on something ranged from 77.14 to 90.92 percent. All the sessions are positive feedback given by students who strongly agree and biosafety, E-learning, language, and biomedical waste management needed improvement in the module. Good collaboration, teamwork, and thorough planning at the interdepartmental and intradepartmental levels, according to the faculty, were vital elements for the course's successful implementation.

Conclusion: The foundation course sessions were generally well welcomed by the students. The findings will aid us in improving our foundation programme for the following year to accomplish the goals of the foundation course.
Grading of Hashimoto’s thyroiditis in cytology and its association with ultrasonographic and biochemical parameters
Authors: Saldanha Crysle , Fernandes Hilda , C. S. Jayaprakash 
Published: November 2023

Introduction and Aim: In the post-iodization period, Hashimoto's thyroiditis (HT) is most likely the most prevalent cause of goitre and hypothyroidism, particularly in women of reproductive years. This study was undertaken to grade HT on Fine Needle Aspiration Cytology smears and determine their usefulness in predicting thyroid damage in association with clinical history, radiological and biochemical findings.

Materials and Methods: Total of 151 cases were diagnosed cytologically in duration of over 2 years as Hashimoto’s thyroiditis/lymphocytic thyroiditis. Cytology scoring technique was used to analyse smears and were correlated with radiological, biochemical findings and were evaluated statistically by ANOVA and Kruskal Wallis tests.

Results: In the current study, the most frequent group of individuals with Hashimoto's thyroiditis were between the ages of 40 and 50. Females (145 cases, 96%) were commonly affected and the commonest presentation was a diffuse (125 cases ,82.8%) thyroid enlargement. Cytological grading of Hashimoto’s thyroiditis were as follows,54 (35.8%) patients were Grade I, 81(53.6%) patients were Grade II thyroiditis and 16 (10.6%) patients were Grade III thyroiditis. Biochemically, 78 (56.5%) of the cases were hypothyroid, 51 (37%), euthyroid, and 9 (6.5%) were hyperthyroid. Ultrasonography revealed 76 (50.3%) patients with hypoechoic micronodules, 71 (47%) with echogenic septae, 101 (66.9%) with increased vascularity, and 6 (4%) with normal findings. The grades of lymphocytic thyroiditis and the biochemical data were found to be statistically significant (p=0.001). Furthermore, there was a strong correlation between the grades and specific ultrasound findings, such as echogenic septae (p=0.042) and diffuse hypoechogenicity (p=0.046).

Conclusion: Cytological scoring system in Hashimoto’s thyroiditis can predict thyroid functional status and aid in determining the severity of the disease.