bluuebunny/crossref_metadata_2025_split huggingface dataset:
Antioxidant activity of Flemingia praecox and Mucuna pruriens and their implications for male fertility improvement
Authors: Kumbhare Shravan D. , Ukey Sanghadeep S. , Gogle Dayanand P. 
Published: November 2023

AbstractGlobally, 15–24% couples are unable to conceive naturally and 50% of cases of this problem are due to infertility in males. Of this, about 50% of male infertility problems are developed due to unknown reasons called as idiopathic infertility. It is well established that, reactive oxygen species (ROS) have negative impact on male fertility and are involved in 80% of total idiopathic male infertility cases. Medicinal plants are considered as an alternative approach for mitigating the health problems. The plants with good antioxidant capacity can improve the male infertility symptoms generated by ROS. Such medicinal plants can be used to alleviate the symptoms of male infertility with their diverse phytoconstituents. Mucuna pruriens is a well-accepted herb, with its seeds being used to improve the male fertility in various ways and one of the ways is by eliminating the ROS. In our field survey, another plant, Flemingia praecox, although less known, its roots are used in all problems related to the male fertility by tribal people of the Gadchiroli district of Maharashtra, India. The study was conducted to determine in vitro antioxidant potential of F. praecox and compared the results with the well-established male fertility improving plant M. pruriens with special emphasis on medicinally important roots of F. praecox and seeds of M. pruriens. The objective of the study was investigated by studying their total phenol (TPC) and flavonoid (TFC) content, antioxidant parameters (DPPH, FRAP, ABTS, DMPD, β-carotene bleaching and TAA) and finally DNA damage protection capacity of the plant extracts was studied. The plant parts used for the medicinal purposes have been investigated along with other major parts (leaves, stem and roots of both the plants) and compared with synthetic antioxidants, BHA, BHT and ascorbic acid. Moreover, the inhibition of two male infertility enzyme markers, PDE5 and arginase by F. praecox root and M. pruriens seed extract was also studied in vitro. The results showed that F. praecox possesses higher antioxidant activity than M. pruriens in the majority of studies as observed in TFC, DPPH, TAA, ABTS and DMPD assays. However, M. pruriens seeds showed best results in TPC, FRAP and DNA damage protection assay. F. praecox root extract also gave better PDE5 inhibition value than M. pruriens seeds. This study will help to establish the authenticity of F. praecox used by tribal people and will encourage its further use in managing the male infertility problems.
Americans weigh an attended emotion more than Koreans in overall mood judgments
Authors: Son Gaeun , Im Hee Yeon , Albohn Daniel N. , Kveraga Kestas , Adams Reginald B. , Sun Jisoo , Chong Sang Chul 
Published: November 2023

AbstractFace ensemble coding is the perceptual ability to create a quick and overall impression of a group of faces, triggering social and behavioral motivations towards other people (approaching friendly people or avoiding an angry mob). Cultural differences in this ability have been reported, such that Easterners are better at face ensemble coding than Westerners are. The underlying mechanism has been attributed to differences in processing styles, with Easterners allocating attention globally, and Westerners focusing on local parts. However, the remaining question is how such default attention mode is influenced by salient information during ensemble perception. We created visual displays that resembled a real-world social setting in which one individual in a crowd of different faces drew the viewer's attention while the viewer judged the overall emotion of the crowd. In each trial, one face in the crowd was highlighted by a salient cue, capturing spatial attention before the participants viewed the entire group. American participants’ judgment of group emotion more strongly weighed the attended individual face than Korean participants, suggesting a greater influence of local information on global perception. Our results showed that different attentional modes between cultural groups modulate social-emotional processing underlying people’s perceptions and attributions.
Investigation of the relationship between pulmonary lesions based on lung ultrasound and respiratory clinical signs in foals with suspected pulmonary rhodococcosis
Authors: Rakowska Alicja , Czopowicz Michał , Bereznowski Andrzej , Witkowski Lucjan 
Published: November 2023

AbstractRhodococcus equi is a widely recognized bacterium responsible for pneumonia in preweaned foals. On endemic farms, foals with a subclinical course of the disease usually outnumber those presenting clinical signs. The disease is typically chronic and mainly manifests as fever and dyspnoea. Currently, field diagnosis is often based on lung ultrasound (LUS); however, both diagnostic and therapeutic approaches vary among practitioners and considerably change over time. This longitudinal, prospective study was designed to describe the appearance and progression of rhodococcal pulmonary lesions during the first months of life based on LUS and to evaluate the relationship between the presence and severity of rhodococcal pulmonary lesions and the occurrence of respiratory clinical signs in foals from farms with endemic R. equi infections. Nearly 26% of foals demonstrated respiratory signs highly suggestive of pulmonary rhodococcosis, and approximately 70% of the foals had abnormalities detected on LUS without concurrent clinical signs. The appearance and development of LUS abnormalities were age-related. An abscess diameter exceeding 15 mm in LUS and other pleural lesions were significantly linked with the occurrence of clinical signs suggestive of pulmonary rhodococcosis (P < 0.001) and may be considered predictive factors of rhodococcal pneumonia in foals.
Causal effect of physical activity and sedentary behaviors on the risk of osteoarthritis: a univariate and multivariate Mendelian randomization study
Authors: Li Xingzhao , Wang Sibo , Liu Wanguo , Wu Han , Zhu Yuhang 
Published: November 2023

AbstractThere is still a lot of ambiguity about the link between physical activity (PA), sedentary behaviors (SBs) and osteoarthritis (OA). This study aimed to investigate the causal relationship of PA/SBs on the risk of OA. A univariate and multivariate Mendelian randomization (MR) analysis was conducted to investigate the causal effect of five PA phenotypes and three SB phenotypes on overall OA, knee OA, hip OA, total hip arthroplasty, and total knee arthroplasty (TKA). MR methods used were inverse-variance weighting, MR-Egger regressions, and weighted median. Sensitivity analysis examined horizontal pleiotropy and heterogeneity, and confirmed the reliability of the results. After false discovery rate, light do-it-yourself (DIY) activities decreased the risk for overall OA (OR: 0.32, 95% CI 0.16–0.65), and knee OA (OR: 0.26, 95% CI 0.12–0.51). Resulting in a decreased risk of walking for pleasure on overall OA (OR: 0.87, 95% CI 0.70–1.04) and knee OA (OR: 0.14, 95% CI 0.06–0.32) was also observed. Television viewing, however, significantly increased the risk of OA, knee OA, hip OA, and TKA. MVMR findings revealed independent causal impacts of walking for pleasure and watching television on overall and knee OA, taking into account BMI, smoking, and education. This study suggested that light DIY and walking for pleasure were beneficial for preventing OA, and the risk of OA and TKA increased with prolonged television watching.
Testing the Informativeness of Diverse Measures of Auditory Processing for Clinical Audiological Practice in Middle-Aged Adults in Mexico
Authors: Lelo de Larrea-Mancera E. Sebastian , Solís-Vivanco Rodolfo , Sánchez-Jiménez Yolanda , Padilla-Bustos Katia , Correa-Medina Erick I. , Clamage David S. , Bologna William J. , Gallun Frederick J. , Seitz Aaron R. 
Published: November 2023

Purpose:
Standard clinical audiologic assessment is limited in its ability to capture variance in self-reported hearing difficulty. Additionally, the costs associated with clinical testing in audiology create financial barriers for hearing health care in developing countries like Mexico. This study used an open-source Spanish-language tool called PART (Portable Automated Rapid Testing) to test the hypothesis that a battery of assessments of auditory processing can complement standard clinical audiological assessment to better capture the variance of self-reported hearing difficulty.

Method:
Forty-three adults between 40 and 69 years of age were tested in Mexico City using a traditional clinical pure-tone audiogram, cognitive screening, and a battery of PART-based auditory processing assessments including a speech-on-speech competition spatial release from masking task. Results were compared to self-reported hearing difficulty, assessed with a Spanish-language adaptation of the Hearing Handicap Inventory for the Elderly–Screening Version (HHIE-S).

Results:
Several measures from the PART battery exhibited stronger correlations with self-reported hearing difficulties than the pure-tone audiogram. The spatial release from masking task best captured variance in HHIE-S scores and remained significant after controlling for the effects of age, audibility, and cognitive score.

Conclusions:
The spatial release from masking task can complement traditional clinical measures to better account for patient's self-reported hearing difficulty. Open-source access to this test in PART supports its implementation for Spanish speakers in clinical settings around the world at low cost.

Supplemental Material:

https://doi.org/10.23641/asha.24470140
A Novel Radiological Classification System of the Proximal Humerus
Authors: Sangaletti Rudy , Abuljadail Salahulddin , Akkaya Mustafa , Zanna Luigi , Gehrke Thorsten , Citak Mustafa 
Published: November 2023

AbstractDifferent anatomical variants have been reported for the proximal and distal femur. Given this context, the goal of our study was to answer the following question: Can we also identify different anatomical variants of the proximal humerus?Two hundred anteroposterior (AP) radiographs of the proximal humerus with an equal gender distribution and equal laterality per gender were reviewed. The metaphyseal diameter of the proximal humerus at the level of the anatomical neck (X) and the intramedullary diameter at 10 cm from the apex of the greater tuberosity (Y) were measured. A new ratio was established, based on both measurements (Y/X). Radiographs showed different anatomical variants: type A: Y/X < 0.3, type B: Y/X = 0.3–0.4, type C: Y/X > 0.4. Two observers reviewed the AP radiographs independently and blindly in 2 different sessions.Three different anatomical groups (A, B and C) were identified based on the 25th and 75th percentiles. A higher percentage of type C was observed among females and a higher percentage of type A among males. A high inter-observer reliability was noted, with a Cronbach’s alpha of 0.97 (ICC 0.96–0.98). The intra-observer reliability for observer 1 had a Cronbach’s alpha of 0.98.A novel radiological classification of the proximal humerus has been established based on 3 different anatomical types (A, B and C). Further studies are needed to establish whether the novel classification system can be used as an indicator for aseptic loosening of cemented or cementless total shoulder arthroplasty.
Synergism Between Essential Oils and Evaluation of Their Activities with a Focus on Malassezia furfur Control
Authors: Cassola Fábio , Ramírez Nedy , Ribeiro Guilherme , da Silva Lucas Henrique Domingos , Gambero Alessandra , de Oliveira Adriana da Silva Santos , Vieira Pedro Manoel Mendes de Moraes , Nogueira Flávia Aparecida Resende , Duarte Marta Cristina Teixeira 
Published: November 2023

AbstractSeborrheic dermatitis is a chronic inflammatory disease caused by Malassezia yeast species that affects the regions of the body where the sebaceous glands are present. The combined
use of different essential oils (EOs) can increase their spectrum of action. Thus, the present study aimed to evaluate the action of EOs alone and in combination with each other on
M. furfur, in planktonic and biofilm form, and their anti-inflammatory and mutagenic potential, in addition to the effects on the viability of cells lines. Of the 40 evaluated EOs, 22
showed activity against M. furfur at 0.5 – 2.0 mg/mL concentrations. Among the most active species, a blend of essential oils (BEOs) composed of Cymbopogon martini (Roxb.)
Will. Watson (MIC = 0.5 mg/mL) and Mentha × piperita L. (MIC = 1.0 mg/mL) was selected, which showed a synergistic effect against yeast when evaluated through the checkerboard
assay. The fungicidal activity was maintained by the addition of anti-inflammatory oil from Varronia curassavica Jacq. to BEOs. The BEOs also showed activity in the inhibition of
biofilm formation and in the eradication of the biofilm formed by M. furfur, being superior to the action of fluconazole. Furthermore, it did not show mutagenic potential and did not
interfere with the cell viability of both evaluated cell lines (HaCaT and BMDMs). TNF-α levels were reduced only by C. martini; however, this property was maintained when
evaluating BEOs. BEOs had no effect on IL-8 levels. Thus, the BEOs may be indicated for alternative treatments against seborrheic dermatitis.
Role of Permeability Surface Area Product in Grading of Brain Gliomas using CT Perfusion
Authors: Agrawal Ira , Bano Shahina , Chaudhary Ajay , Ahuja Arvind 
Published: November 2023

Abstract
Purpose The aim of this study was to evaluate the role of permeability surface area product in grading brain gliomas using computed tomography (CT) perfusion
Materials and Methods CT perfusion was performed on 33 patients with brain glioma diagnosed on magnetic resonance imaging. Of these, 19 had high-grade glioma and 14 had low-grade glioma on histopathological follow-up. CT perfusion values were obtained and first compared between the tumor region and normal brain parenchyma. Then the relative values of perfusion parameters were compared between high- and low-grade gliomas. Cut-off values, sensitivity, specificity, and strength of agreement for each parameter were calculated and compared subsequently. A conjoint factor (permeability surface area product + cerebral blood volume) was also evaluated since permeability surface area product and cerebral blood volume are considered complimentary factors for tumor vascularity.
Results All five perfusion parameters namely permeability surface area product, cerebral blood volume, cerebral blood flow, mean transit time, and time to peak were found significantly higher in the tumor region than normal brain parenchyma. Among these perfusion parameters, only relative permeability surface area product and relative cerebral blood volume were found significant in differentiating high- and low-grade glioma. Moreover, relative permeability surface area product was significantly better than all other perfusion parameters with highest sensitivity and specificity (97.74 and 100%, respectively, at a cut-off of 9.0065). Relative permeability surface area product had a very good agreement with the histopathology grade. The conjoint factor did not yield any significant diagnostic advantage over permeability surface area product.
Conclusion Relative permeability surface area product and relative cerebral blood volume were helpful in differentiating high- and low-grade glioma; however, relative permeability surface area product was significantly better than all other perfusion parameters. Grading brain gliomas using relative permeability surface area product can add crucial value in their management and prognostication; hence, it should be evaluated in the routine CT perfusion imaging protocol.
Comparison of Cardiac Indices Using Two Different Concentrations of Topical Adrenaline during Endoscopic Transsphenoidal Pituitary Surgery: A Prospective Randomized Observational Study
Authors: Gautam Archana , Haldar Rudrashish , Srivastava Shashi , Gupta Devendra , Jaiswal Awadhesh Kumar , Mishra Prabhaker 
Published: November 2023

Abstract
Introduction Adrenaline-soaked wicks are often employed to decongest nasal mucosa during transsphenoidal pituitary surgeries to ensure proper hemostasis and visibility of the operating field. Considerable debate exists regarding the optimum concentration of adrenaline that strikes a balance between hemostasis as well as the hemodynamic side effects of adrenaline. This study assessed cardiac indices like cardiac output and cardiac index using a FloTrac Vigileo cardiac output monitor to compare two different concentrations of adrenaline used for topical instillation.
Materials and Methods 60 adult patients undergoing transsphenoidal pituitary surgery were randomly assigned to receive cotton wicks soaked in adrenaline solution (either 1:100,000 or 1:200,000) for nasal decongestion. Following a standardized anesthetic regime, a FloTrac Vigileo cardiac output monitor was attached with the invasive arterial line for precise monitoring and recording of cardiac indices (cardiac output and cardiac index). Additionally, quality of surgical field (as reported by the operating surgeon) blood loss, incidences of adverse hemodynamic events, and rescue drug usage were recorded.
Results No difference in cardiac outputs and cardiac indexes of the patients was observed during baseline to 55 minutes and at 80 minutes and onward, whereas difference rose to statistical significance at the time points of 60 minutes and 70 minutes (p < 0.05). Other parameters like stroke volume, stroke volume variation, and hemodynamic parameters were similar. Quality of the surgical fields (as reported by the surgeon), intraoperative bleeding, incidences of adverse effects, and frequency of rescue drugs usage were similar.
Conclusion Instillation of 1:100,000 dilution of adrenaline solution compared with 1:200,000 for nasal decongestion is associated with significant rise in cardiac output and cardiac index at 60 and 70 minutes of the surgery with similar blood loss and hemodynamic variables. Therefore, the lower concentration of adrenaline can be recommended for usage during transsphenoidal pituitary surgeries.
Bifrontal–Parietal Ratio: A Novel Risk Factor for Cerebrospinal Fluid Overdrainage after Ventriculoperitoneal Shunting
Authors: Chaisawasthomrong Chonnawee , Saetia Kriangsak 
Published: November 2023

Abstract
Objective This study aimed to examine potential risk factors associated with cerebrospinal fluid overdrainage after ventriculoperitoneal (VP) shunting.
Materials and Methods We retrospectively examined the medical records of hydrocephalus patients who underwent VP shunting at a single institution between January 2011 and December 2017 and had a minimum 3-year follow-up. Variables studied included age, gender, hydrocephalus etiology, symptoms, shunt valve, ventricular catheter entry point, and neurosurgical history, including history of external ventricular drainage. Radiographic variables included Evans index, bicaudate index, callosal angle, measurements of frontal lobe thickness, and bifrontal–parietal ratio.
Results Among the 182 study patients, 11 experienced overdrainage. Age, gender, etiology, symptoms, and surgical history did not significantly differ between patients who experienced overdrainage and those who did not. Evans index, bicaudate index, and callosal angle did not significantly differ between the groups. Measurements of frontal lobe thickness and bifrontal–-parietal ratio were significantly lower in the overdrainage group.
Conclusion Bifrontal–parietal ratio may be useful to predict overdrainage after VP shunt surgery.
Arthroscopic Wafer Procedure for Ulnar Impaction Syndrome in an Intact Triangular Fibrocartilage Complex
Authors: Choudhury Muntasir Mannan , Sajeev Suraj , Sheng Brandon Yew Bao , Wijetunga Dashishka Thanuranga , Chin Andrew Yuan Hui 
Published: November 2023

AbstractUlnocarpal impaction or ulnar abutment symptom occurs secondary to abnormal load bearing on the ulnar side of the wrist leading to pain symptoms and degeneration of the structures of the ulnocarpal joint.The two classical surgical methods used to address this problem are ulnar shortening osteotomy and the wafer procedure, which can either be open or arthroscopic. With the advent of arthroscopy, with surgeon harboring arthroscopy skills, arthroscopic wafer resection has been intensely popularized which requires a central perforation of the triangular fibrocartilage to approach the ulna dome through the ulnocarpal joint.So, what happens in symptomatic patients with ulnocarpal abutment with an intact triangular fibrocartilage complex who have failed conservative management. Do we perform an open procedure or do we create a perforation in the central disc of the triangular fibrocartilage complex to expose the ulnar dome? Or do we just do an ulnar shortening osteotomy?Here, we describe our arthroscopic technique of conducting arthroscopy in the narrow confines of the space below the triangular fibrocartilage complex above the ulnar dome to carry out an arthroscopic wafer procedure in a triangular fibrocartilage complex with no central perforation. The procedure can produce results similar to those of the classical arthroscopic wafer procedure described explicitly in the literature.
Birds pre-adapted to a road in a heterogeneous and contiguous old-growth forest: a point transect study
Authors: Fulton Graham R. , Beher Jutta , Possingham Hugh P. 
Published: November 2023

Roads are present globally across all habitats and their negative impacts on the landscape are being increasingly reported. Yet often more is known about the identity of roadkill than how avian assemblages are impacted by roads. This study used 100 paired point counts by the road and 400 m into the forest interior to assess if the assemblages were different and determine what species may be impacted by the road. The study was undertaken along a highway cut through one of the world’s tallest forests – old-growth karri (Eucalyptus diversicolor) forest of south-western Australia. There was no overall significant difference in species richness and abundance between road and forest interior sites, although a small number of species (4.3%) did demonstrate preferences. Overall, we suggest that the limited significant differences resulted from: (1) the narrowness of the road with the forest canopy frequently extended fully across and (2) the natural variation found in eucalypt forests, which has aided the birds as a pre-adaptation to the presence of this road – because eucalypt forests are a heterogeneous array of streams and forest heterogeneity.
A spherical version of Feynman’s static field momentum example
Authors: Johns Oliver Davis 
Published: November 2023

Abstract
The Feynman demonstration that electromagnetic field momentum is real—even for static fields—can be made more pedagogically useful by simplifying its geometry. Instead of Feynman’s disk with charged balls on its surface, this article uses the geometry of a hollow non-conducting sphere with uniform surface charge density. With only methods available in a typical upper-division electrodynamics course, the initial field angular momentum and the final mechanical angular momentum can then be calculated in closed form and shown to be equal.