bluuebunny/crossref_metadata_2025_split huggingface dataset:
Gastric adenocarcinoma in Situs inversus totalis: a case study and literature review
Authors: Sun Bo , Xu Ping , Kong Pengfei , Fang Yantian , Fu Hong 
Published: October 2023

BackgroundSitus inversus totalis (SIT) is an uncommon disorder characterized by mirror-image anatomy, which can present unique challenges and potential vascular anomalies in surgical interventions, particularly in gastric cancer patients.AimsWe aim to delineate a rare case of gastric adenocarcinoma in a SIT patient and conduct a thorough review of the existing literature concerning surgical strategies, vascular anomalies, and outcomes observed across varied geographic locales and technological approaches.MethodsA thorough examination of a case involving a 39-year-old male SIT patient who underwent a successful distal gastrectomy with D2 lymph node dissection is presented alongside an expansive literature review. The review encompasses 47 articles, collating data on surgical approaches and vascular anomalies across 49 patients diagnosed with SIT and gastric cancer.ResultsThe patient underwent curative distal gastrectomy and Billroth II with Braun anastomosis within 95 minutes, incurring minimal intraoperative blood loss (100ml). Postoperative pathology confirmed moderately to poorly differentiated gastric adenocarcinoma (pT3N0M0), with no signs of recurrence or metastasis after 6 months of S-1 adjuvant chemotherapy. The literature review revealed vascular anomalies in approximately 20% of reported cases, accentuating its surgical significance. Noteworthy variations in surgical strategies, operative times, blood loss, and complications across different surgical modalities were observed, providing a comprehensive view into the practical management of such cases.ConclusionDespite the inherent challenges associated with SIT, various surgical techniques can be successfully applied with meticulous preoperative planning and understanding vascular anomalies. This compilation of diverse surgical experiences across numerous documented cases seeks to provide a consolidated resource for refining surgical strategies and enhancing postoperative outcomes for gastric cancer patients with SIT, underscoring the imperativeness of further research in this niche domain.
Habitat-based radiomics enhances the ability to predict lymphovascular space invasion in cervical cancer: a multi-center study
Authors: Wang Shuxing , Liu Xiaowen , Wu Yu , Jiang Changsi , Luo Yan , Tang Xue , Wang Rui , Zhang Xiaochun , Gong Jingshan 
Published: October 2023

IntroductionLymphovascular space invasion (LVSI) is associated with lymph node metastasis and poor prognosis in cervical cancer. In this study, we investigated the potential of radiomics, derived from magnetic resonance (MR) images using habitat analysis, as a non-invasive surrogate biomarker for predicting LVSI in cervical cancer.MethodsThis retrospective study included 300 patients with cervical cancer who underwent surgical treatment at two centres (centre 1 = 198 and centre 2 = 102). Using the k-means clustering method, contrast-enhanced T1-weighted imaging (CE-T1WI) images were segmented based on voxel and entropy values, creating sub-regions within the volume ofinterest. Radiomics features were extracted from these sub-regions. Pearson correlation coefficient and least absolute shrinkage and selection operator LASSO) regression methods were used to select features associated with LVSI in cervical cancer. Support vector machine (SVM) model was developed based on the radiomics features extracted from each sub-region in the training cohort.ResultsThe voxels and entropy values of the CE-T1WI images were clustered into three sub-regions. In the training cohort, the AUCs of the SVM models based on radiomics features derived from the whole tumour, habitat 1, habitat 2, and habitat 3 models were 0.805 (95% confidence interval [CI]: 0.745–0.864), 0.873(95% CI: 0.824–0.922), 0.869 (95% CI: 0.821–0.917), and 0.870 (95% CI: 0.821–0.920), respectively. Compared with whole tumour model, the predictive performances of habitat 3 model was the highest in the external test cohort (0.780 [95% CI: 0.692–0.869]).ConclusionsThe radiomics model based on the tumour sub-regional habitat demonstrated superior predictive performance for an LVSI in cervical cancer than that of radiomics model derived from the whole tumour.
Dehydroalanine and dehydrobutyrine in aging and cataractous lenses reveal site-specific consequences of spontaneous protein degradation
Authors: Paredes Jessica , Wang Zhen , Patel Purvi , Rose Kristie L. , Schey Kevin L. 
Published: October 2023

IntroductionProtein post-translational modifications (PTMs) have been associated with aging and age-related diseases. PTMs are particularly impactful in long-lived proteins, such as those found in the ocular lens, because they accumulate with age. Two PTMs that lead to protein-protein crosslinks in aged and cataractous lenses are dehydroalanine (DHA) and dehydrobutyrine (DHB); formed from cysteine/serine and threonine residues, respectively. The purpose of this study was to quantitate DHA and DHB in human lens proteins as a function of age and cataract status.MethodsHuman lenses of various ages were divided into five donor groups: transparent lenses (18–22-year-old, 48–64-year-old, and 70–93-year-old) and cataractous human lenses of two age groups (48–64-year-old lenses, and 70–93-year-old lenses) and were subjected to proteomic analysis. Relative DHA and DHB peptide levels were quantified and compared to their non-modified peptide counterparts.ResultsFor most lens proteins containing DHA or DHB, higher amounts of DHA- and DHB-modified peptides were detected in aged and cataractous lenses. DHA-containing peptides were classified into three groups based on abundance changes with age and cataract: those that (1) increased only in age-related nuclear cataract (ARNC), (2) increased in aged and cataractous lenses, and (3) decreased in aged lenses and ARNC. There was no indication that DHA or DHB levels were dependent on lens region. In most donor groups, proteins with DHA and DHB were more likely to be found among urea-insoluble proteins rather than among water- or urea-soluble proteins.DiscussionDHA and DHB formation may induce structural effects that make proteins less soluble in water that leads to age-related protein insolubility and possibly aggregation and light scattering.
VeryFastCCD: a high frame rate soft X-ray detector
Authors: Goldschmidt Azriel , Grace Carl , Joseph John , Krieger Amanda , Tindall Craig , Denes Peter 
Published: October 2023

Direct X-ray detection in silicon has been transformative for scattering experiments in biology and materials science. While bump-bonded hybrid pixels have been attractive for hard X-ray detection, the challenge for single photon soft X-ray detection is sufficiently low noise. CCD structures on thick, high-resistivity silicon have been successfully used as sensors over the range of soft to hard X-rays at storage rings and FELs. The VeryFastCCD is a high frame rate, column-parallel CCD sensor with 48 μm pixels. Combined with 256-channel custom readout ASICs, frame rates of 5–10 kHz have been achieved with readout noise as low as 20 e and full-well capacity &gt;4 × 105 e/pixel. Thin (10 nm and 100 nm) entrance window contact processes have also been developed which provide &gt;85% quantum efficiency for 285 eV X-rays. Systems are currently being developed for several beamlines at the upgraded Advanced Light Source.
Scalable agritech growbox architecture
Authors: Kirwan R. F. , Abbas F. , Atmosukarto I. , Loo A. W. Y. , Lim J. H. , Yeo S. 
Published: October 2023

Introduction: Urban farming has gained prominence in Singapore, offering opportunities for automation to enhance its efficiency and scalability. This study, conducted in collaboration with a leading Singaporean urban farming company, introduces an IoT-based automated farming system. This system incorporates an agnostic growbox and a web application dashboard for intelligent monitoring of crop growth. The presented approach provides an open-source and cost-effective solution for a scalable urban farming architecture. The agnostic growbox system offers both accessibility and scalability, utilizing cost-effective and modular hardware components with open-source software, thereby increasing customizability and accessibility compared to commercial growbox products. The authors anticipate that this approach will find diverse applications within the realm of urban farming, streamlining, and improving the efficiency of urban farming through automation.Methods: The study employs an integrated solution that incorporates an image analytics approach for the proficient and accurate classification of crop disease phenotypes, specifically targeting chlorosis and tip burn in lettuce crops. This approach is designed to be hardware- and software-efficient, obviating the necessity for extensive image datasets for model training. The image analytics approach is compared favourably with a machine learning approach, evaluating the accuracy of categorization using the same dataset. Additionally, the approach is assessed in terms of time and cost efficiency in comparison to machine learning techniques.Results: The image analytics approach demonstrated notable scalability, time efficiency, and accuracy in the detection of crop diseases within urban farming. Early detection, particularly of chlorosis and tip burn, proves critical in mitigating crop wastage. The results indicate that the integrated solution provided a reliable and effective means of disease classification, with significant advantages over traditional machine learning approaches in terms of time and cost efficiency.Discussion: The presented IoT-based automated farming system, incorporating the agnostic growbox and image analytics approach, holds promise for revolutionizing urban farming practices. Its open-source nature, coupled with cost-effectiveness and scalability, positions it as a practical solution for urban farming architecture. The system's ability to efficiently detect and classify crop diseases, particularly chlorosis and tip burn, offers a substantial contribution to reducing wastage and enhancing crop yield. Overall, this approach paves the way for a more efficient and sustainable future for urban farming through the integration of automation and advanced analytics. Further exploration and implementation of this technology in diverse urban farming settings is warranted.
Analysis of the Effect of Pulse Width on Nonlinear Thomson Scattering from an Applied Magnetic Field
Authors: Wang Haokai , Gu Feiyang , Zhang Yi , Wang Yubo , Tian Youwei 
Published: October 2023

The effects of magnetic fields on electron dynamics, spatially radiated power, and radiation spectra in tightly focused circularly polarized laser pulses are studied in detail. The laser wavelength λ0=1 μm. As the pulse width increases from λ0 to 6λ0, the electron dynamics, spatially radiated power, and spectral properties stabilize, and the benefit that can be enhanced by increasing the pulse width decreases continuously, i.e., saturation is reached. However, although the benefits are better at pulse widths equal to 6λ0, to obtain high-energy, highly collimated X-rays, tightly focused circularly polarized laser pulses with larger pulse widths is better.
Topical Issues of Clinical Transfusiology
Authors: Ваганова Т.В. , Карпенко Ф.Н. 
Published: October 2023

В Республике Беларусь трансфузиологическая помощь (ТП) организована в соответствии с требованиями законодательства, с целью обеспечения ее доступности, безопасности и эффективности. Структура ТП включает в себя учреждения службы крови и организации здравоохранения, оказывающие ТП, медицинское применение крови, ее компонентов. При этом каждое звено имеет четкий регламент локальной организации и взаимодействия. Профилактика трансфузионных реакций и посттрансфузионных осложнений (ТР и ПТО) основана на соблюдении требований безопасности заготовки и производства, а также медицинского применения крови, ее компонентов, разработки и внедрения новых методов и средств трансфузиологического пособия. Неотъемлемой частью оказания ТП является анализ ее объема и структуры с целью обеспечения и повышения качества.
In the Republic of Belarus, transfusion assistance is organized in accordance with the requirements of the legislation, ensuring its availability, safety and efficiency. The structure of transfusion care includes blood institutions and health organization services that provide transfusion care, medical use of blood and its components. At the same time, each link has a clear regulation of local organization and interaction. Prevention of transfusion reactions and post-transfusion complications is based on compliance with the safety requirements for procurement and production, as well as the medical use of blood and its components, the development and implementation of new methods and means of transfusion assistance. An integral part of the provision of transfusiological care is the analysis of its volume and structure in order to ensure and improve quality.
Hubungan antara Aktivitas Fisik dan Kecemasan pada Remaja di SMP Katolik Santa Theresia Malalayang
Authors: Wewengkang Rindiani B. E. , Kairupan Bernabas H. R. , Munayang Herdy 
Published: October 2023

Abstract: Anxiety is a common mental disorder that occurs not only among adults but also in children and adolescents. Physical activity is one of the factors that can influence mental health, reduce symptoms of anxiety, and increase fitness. For adolescents, physical activity is an integral part of them in school, social environment, and family life. This study aimed to analyze the relationship between physical activity and anxiety in adolescents at SMP Katolik Santa Theresia Malalayang (junior high school). This was an analytical and descriptive study with a cross-sectional design. Determination of samples used stratified random sampling technique. Data were analyzed with the chi-square test. The results showed that there were 77 students as respondents. The chi- square test resulted in a p-value of 0.64 (p>0.05). In conclusion, there is no significant relationship between physical activity and anxiety in adolescents at SMP Katolik Santa Theresia Malalayang.
Keywords: physical activity; anxiety; mental disorders; adolescents

Abstrak: Kecemasan merupakan suatu gangguan mental yang umum terjadi baik pada kalangan dewasa maupun di kalangan anak dan remaja. Diketahui bahwa aktivitas fisik dapat memengaruhi kesehatan mental, mengurangi gejala kecemasan, dan meningkatkan kebugaran. Bagi anak usia remaja aktivitas fisik menjadi bagian yang tidak terpisahkan baik dalam kehidupan sekolah, sosial atau keluarga. Penelitian ini bertujuan untuk menganalisis hubungan antara aktivitas fisik dan kecemasan pada remaja di SMP Katolik Santa Theresia Malalayang. Jenis penelitian ialah deskriptif analitik dengan desain potong lintang. Penentuan sampel menggunakan teknik stratified random sampling dengan uji statistik Chi-Square. Hasil penelitian mendapatkan sebanyak 77 siswa sebagai responden penelitian. Hasil uji chi-square mendapatkan nilai p=0,64 (p>0,05) untuk hubungan antara aktivitas fisik dan kecemasan. Simpulan penelitian ini ialah tidak terdapat hubungan bermakna antara aktivitas fisik dan kecemasan pada siswa di SMP Katolik Santa Theresia Malalayang.
Kata kunci: aktivitas fisik; kecemasan; gangguan mental; remaja
Utilization Of Medicinal Plants In West Mapanget Village, Mapanget District, Manado City
Authors: Fitria  , Pangemanan Euis F. S , Lasut Marthen Th 
Published: October 2023

Traditional medicinal plants are types of plants that are believed by humans to treat several diseases and have been used for generations until now. This study aims to identify the types of medicinal plants and know how to use and process them. The method used in this study is the method of observation and interviews using a questionnaire. Sampling using purposive sampling technique to 30 respondents, namely people who use medicinal plants. There are 27 species of plants from 17 families that are used as traditional medicine, with the most members being lamiaceae (4 species). the benefits of medicinal plants, namely: treating internal wounds such as dead blood, healing body aches and lowering blood pressure, curing kidney disease, smoothing menstruation or menstruation in women, treating diabetes and high blood pressure, curing coughs and high blood pressure, treating pain stomach, back pain and itching, relieves tingling, cures coughs, ulcers, heart disease and canker sores treats poisoning, treats the liver, smoothes chapters, stops blood when injured, promotes urination, cures cholesterol and stomach acid, treats boils and headaches. How to use: drink before eating, after eating, and taped/pasted Method of processing: boiled, brewed, pounded, crushed, glued/pasted.
Keywords: medicinal plants, West Mapanget
Abstrak
Tumbuhan obat tradisional adalah jenis tumbuhan yang dipercaya oleh manusia yang berfungsi untuk mengobati beberapa penyakit dan telah digunakan secara turun-temurun sampai saat ini. Penelitian ini bertujuan untuk mengidentifikasi jenis tumbuhan obat dan mengetahui cara penggunaan dan pengolahannya. Metode yang digunakan pada penelitian adalah metode observasi dan wawancara menggunakan kuesioner. Pengambilan sampel menggunakan teknik purposive sampling terhadap 30 responden yaitu masyarakat yang menggunakan tumbuhan obat. Terdapat 27 jenis tumbuhan dari 17 famili yang dimanfaatkan sebagai obat tradisional, dengan anggota terbanyak lamiaceae (4 jenis). manfaat tumbuhan obat yaitu: mengobati luka dalam seperti darah mati, menyembuhkan badan pegal-pegal, dan menurunkan tekanan darah, menyembuhkan penyakit ginjal, melancarkan haid atau datang bulan pada perempuan, mengobati sakit gula dan darah tinggi, menyembuhkan batuk dan darah tinggi, mengobati sakit perut, sakit belakang dan gatal-gatal, menghilangkan kesemutan, menyembuhkan batuk, maag, penyakit jantung dan sariawan mengobati keracunan, mengobati liver, untuk melancarkan bab, menghentikan darah ketika luka, melancarkan kencing, menyembuhkan kolesterol dan asam lambung, mengobati bisul dan sakit kepala. Cara penggunaan: diminum sebelum makan, sesudah makan dan direkatkan/tempelkan. Cara pengolahannya: direbus, diseduh, ditumbuk, dilumatkan, direkatkan/tempelkan.

Kata kunci : tumbuhan obat, Mapanget Barat
Ditch Terrace Effect Of Erosion Land Farming In Horticulture In The Village Rurukan Tomohon City.
Authors: Titah Tilda , Kamagi Yani Ezrah B. , Kaunang Djoni , Sinolungan Meldi Tieneke M. 
Published: October 2023

The purpose of this study was to determine the amount of erosion that occurs on sloping land with mound terraces planted with carrots. The research was carried out in the field by making three research plots with a size of 11 m x 4 m, consisting of 1). Traditional bund plots have 11 bunds, 2). The terrace plots of mounds without plastic mulch have 8 mounds and 3). The terrace plots of mounds with plastic mulch have 8 mounds. Erosion measurement results are calculated using the formula: Total weight of eroded soil = (X gram / Y ml) x volume of water in a bucket. Where: X = Weight of oven-dry soil; Y = Total sediment samples (650 ml).
The data obtained is then arranged in the form of tables and graphs and then described descriptively.
The results showed that the most erosion was in plot 2 of 606.3077 gr/plot with a rain intensity of 17.31 mm/hour and the least amount of erosion was in plot 1 of 0.0692 gr/plot with a rain intensity of 5.86 mm/hour.
Keywords: Terraced bunds, Erosion
Abstrak
Tujuan penelitian ini adalah untuk mengetahui besarnya erosi yang terjadi pada lahan miring dengan teras guludan yang ditanami wortel. Penelitian dilakukan di lapangan dengan membuat petak penelitian dengan ukuran 11 m x 4 m sebanyak tiga petak, yang terdiri atas : 1). Petak guludan tradisionil, mempunyai 11 guludan, 2). Petak teras guludan tanpa mulsa plastik, mempunyai 8 guludan dan 3). Petak teras guludan dengan mulsa plastik mempunyai 8 guludan. Data hasil pengukuran erosi, dihitung dengan rumus : Berat total tanah tererosi = (X gram / Y ml) x volume air ember. Di mana : X = Berat tanah kering oven; Y = Jumlah sedimen cuplikan (650 ml).
Data-data yang diperoleh selanjutnya disusun dalam bentuk tabel dan grafik kemudian diuraikan secara deskriptif.
Hasil penelitian diperoleh bahwa erosi terbanyak pada petak 2 sejumlah 606,3077 gr/petak dengan intensitas hujan sebesar 17,31 mm/jam dan jumlah erosi tersedikit pada petak 1 sejumlah 0,0692 gr/petak dengan intensitas hujan 5,86 mm/jam.

Kata kunci : Teras guludan, Erosi
Quantum Hall effect in graphene transferred by water-soluble transfer sheet and home-use laminator
Authors: Suzuki Kyoichi , Ichiki Ryo , Kitazaki Satoshi , Ogawa Yui 
Published: October 2023

Abstract
For electronic device applications, large-area graphene grown on a metal catalyst by CVD requires a transfer to an insulating substrate. Previously, a transfer method that uses water-soluble polyvinyl alcohol and a laminator was proposed. The method is simple, harmless, and does not require advanced facilities. Based on this method, we fabricated fine patterns on graphene transferred onto a SiO2/Si substrate using lithography and investigated their transport properties. The carrier is controlled between the electrons and holes. The quantum Hall effect is observed at low temperatures. This method can be an option for graphene device production.
Optimizing Performance of a Backscatter-Assisted Underlay Network
Authors: Jee Anand , Kalani Bhavya , Prakriya Shankar 
Published: October 2023

<p>In this letter, we consider a secondary network (SN) in which an ambient backscatter device (BD) utilizes the secondary transmitter (ST) signal to communicate its own information to the secondary destination (SD). Optimizing performance of such networks is complicated by signal reflections by the BD. It is shown in this work how the secondary transmit power and the reflection coefficient of the BD can both be jointly optimized using a simple restricted one dimensional search to satisfy the quality of service (QoS) constraints of SN as well as the primary network (PN) while maximizing performance of the backscatter link, which is termed the tertiary network (TN). Only statistical channel knowledge is used for this purpose. It is seen that careful optimization can improve spectral efficiency. Simulations validate the derived analytical expressions.</p>
Molecular Nano Neural Networks (M3N):In-Body Intelligence for the IoBNT
Authors: Angerbauer Stefan , Haselmayr Werner , Enzenhofer Franz , Pankratz Tobias , ￼Khanzadeh Roya , Springer Andreas 
Published: October 2023

<p>Intelligent behavior is an emergent phenomenon observed in biological organisms across all scales. It describes the cooperative behavior of low complexity entities to accomplish complex tasks, which exceed their individual capabilities. This property is particularly important for the Internet of Bio-Nano Things (IoBNT), which consists of Bio-Nano Things (BNTs) used in the human body, where they face many restrictions, such as bio-compatibility and size constraints. In this paper, we present a novel BNT-architecture, called Molecular Nano Neural Networks (M3N), which allows the implementation of intelligence on the micro-/nano-scale. The proposed structure consists of compartments (low complexity entities) that are connected to each other to form a network. Based on reaction and diffusion of molecules in and between connected compartments, this network mimics an artificial neural network, which is an important step towards artificial intelligence in the IoBNT. We provide design guidelines for the proposed M3N and successfully validate it by applying a regression and classification task.</p>
Modulation Effects of Slow, Paced Breathing with Breath Hold on Brain and Heart in Healthy Adults: A Comprehensive Analysis
Authors: Kumar G Pradeep , Adarsh A , Angarai Ganesan Ramakrishnan 
Published: October 2023

<p>We study the variations in the coherence between breathing & EEG as a function of breathing rate, without and with breath hold. </p>