bluuebunny/crossref_metadata_2025_split huggingface dataset:
Caudate lobe-based minimally invasive anatomic hepatectomy: a retrospective study
Authors: Zhang Zhiheng , Peng Jing , Zhu Yican , Cao Yajuan , Han Bing , Yue Yang , Yu Decai 
Published: October 2023

Abstract
Background: Anatomic hepatectomy has become a crucial surgical procedure in the liver section. The function and role of the caudate lobe in anatomic hepatectomy remain unclear. Thus, this study aimed to summarize the efficiency of caudate lobe-based anatomic hepatectomy.
Methods: Three hundred thirty-one cases were enrolled in this retrospective study. They underwent minimally invasive hepatectomy based on caudate lobe-based anatomic hepatectomy theory. The operation time, blood loss, postoperative CRP, and hospital duration were collected for further analysis.
Results: The mean length of G1L was longer than that of G1C. The length of G1C or G1L was negatively correlated with clinical outcomes (bleeding volume, operation time, postoperative CRP, and hospital duration) and the occurrence of operation-associated complications. Further subgroup analysis showed that theclinical outcomes (postoperative CRP and bleeding volume) of patients who underwent right hepatectomy were negatively associated with the length of the G1C, and the length of the G1L wasconnected to the clinical outcome of patients after left hepatectomy.
Conclusion: Based on the outcomes of 331 patientsundergoing hepatectomy, caudate lobe-based anatomic hepatectomy theory was feasible and efficient for anatomic liver sections.
Comparison of Clinical Outcomes of Supercapsular Percutaneously-assisted Approach Total Hip Arthroplasty Versus Conventional Posterior Approach for Total Hip Arthroplasty in Adults: A Systematic Review and Meta-Analysis
Authors: Zhao Yize , Wang Chen , Sun Wenchen , Xie Xinyi , Feng Ganjun 
Published: October 2023

Abstract
OBJECTIVE: This meta-analysis was aimed to compare the postoperative results between SuperPATH and conventional posterior/posterolateral approach (PA).
METHODS: PRISMAP guidelines were followed in this review. CNKI, Wanfang, PubMed, Embase, Cochrane, and Web of Science databases were searched for qualified studies according to the inclusion criteria, and extracted and analyzed the data by Review Manage 5.4 and Stata 16.0.
RESULTS: 36 studies were included. Compared to PA group, SP group had a shorter incision length, less intraoperative blood loss, a shorter hospital stay, ability to act earlier and less postoperative drainage. Hip function (HHS) was significantly improved within three months postoperatively. Pain of hip (VAS) was significantly reduced within one month postoperatively. The state of daily living (BI) was significantly improved within three months. Patients' overall health status (SF-36 score) improved significantly postoperatively. There was no difference in postoperative complications between the two approaches. PA had a shorter operative time and a higher accuracy of prosthesis placement.
CONCLUSION: SuperPATH is worth promoting. It is superior to conventional PA in terms of shorter hospital stay, less blood loss, shorter patient's postoperative bed rest, acceleration of postoperative hip function, and reduction of postoperative pain. However, it requires a longer operative time and implantation of the prosthesis is less accurate than that of PA. SuperPATH requires continued learning by surgeons to minimize the impact of its shortcomings.
Occult retinal neovascularization following intravitreal bevacizumab and laser treatment for retinopathy of prematurity
Authors: Ng Wei Loon , Trinavarat Adisak , Atchaneeyasakul La-ongsri 
Published: October 2023

Abstract

Background:
We present a patient with retinopathy of prematurity (ROP) who developed worsening plus disease after complete regression of stage 3 ROP. The use of fundus fluorescein angiography (FFA) aided the visualization of occult neovascularization that caused the disease progression.
Case presentation:
The patient was at high risk for ROP due to low birth weight of 690 grams and gestational age of 25 weeks. After the diagnosis of stage 3 ROP in zone I without plus disease, she was treated initially with bilateral intravitreal bevacizumab (IVB) and followed by laser photocoagulation 3 weeks later. Despite the resolution of ROP stage, the plus disease worsened. Neither systemic risk factors nor skip laser areas were observed. Hence, FFA was performed and subsequently identified occult neovascularization with active leakage. Additional IVB and laser treatment in the capillary dropout area inside vascularized retina were added. The plus disease improved but mild arteriolar tortuosity persisted.
Conclusions:
Worsening of plus disease after completion of laser ablation and IVB with complete regression of stage 3 ROP is rare. Systemic risk factors such as continuous oxygen therapy and cardiovascular disease should be ruled out. FFA aided in identifying occult neovascularization and prompted further treatment.
Diagnosis accuracy of Raman spectroscopy in the diagnosis of tuberculosis: a meta-analysis
Authors: Cheng ZiHe , Ma Rui , Yu Zixian , Wu Jing , Sun Yanan , Wang Qiaoyun , Li Tiantian , Zhao Jin , Wang Shengyu 
Published: October 2023

Abstract
Background Raman spectroscopy (RS) has shown promise in the diagnosis of tuberculosis (TB). However, the evidence for its diagnostic accuracy in TB is still unclear.
Results This meta-analysis incorporated a total of eight articles. RS exhibited a sensitivity of 0.91 (95% CI, 0.82-0.96) and specificity of 0.94 (95% CI, 0.85-0.97) for TB diagnosis. Importantly, the DOR was 146.18 (95% CI, 42.28-505.42), indicating a favorable discriminative ability. Additionally, the AUC of summary receiver operating characteristic curves was 0.97 (95% CI, 0.95-0.98). Subgroup analysis further indicated that both surface-enhanced Raman spectroscopy (SERS) and the 700-900 nm wavelength group demonstrated even higher sensitivity and specificity, surpassing 0.95. Significant heterogeneity was observed among the included studies; however, the publication bias was considered acceptable based on Deeks’ funnel plot analysis.
Conclusions This meta-analysis suggests that RS may be an effective and accurate tool for differentiating TB. Notably, the application of SERS and the utilization of the 700-900 nm wavelength range further enhance the sensitivity and specificity.
Trial Registration This meta-analysis has been registered at PROSPERO with ID: CRD42023415761.
Screening of Close Contacts of Pulmonary Tuberculosis in an Urban Area in Shanghai, China: a Cross-Sectional Study
Authors: Zhang Shiqi , Li Fen , Jing Chen , Zheyuan Wu , Chenxi Ning , Shen Xin , Yuan Zhengan 
Published: October 2023

Abstract
Objectives: The study aimed to explore the risk factors of close contacts developing pulmonary tuberculosis (TB) and evaluate the socioeconomic benefits of TB prevention and control expenditure in Putuo District, Shanghai.
Study design: A cross-sectional study was conducted among close contacts of pulmonary TB patients in Putuo District from 2017 to 2018.
Methods: A symptom questionnaire, chest X-ray (CXR) and interferon-gamma release assay (IGRA) were carried out to screen the consenting close contacts. Three sputum smears and cultures were collected from close contacts whose screening was positive.
Results: A total of 1036 individuals were included in this study, with an average age of 47.3±19.4 years old, including 427 males and 609 females. Four of the close contacts had suspected TB symptoms. Fourteen had abnormal CXR with suspected TB and 52 had positive IGRA results. Multivariate analysis showed that index cases with positive sputum smears, close contacts with suspected TB symptoms and their interaction term were at significantly higher risk of developing TB. A total of $67,372.6 was invested. Eight active TB cases were screened and successfully treated in this study, saving $88,083.11 by avoiding new cases by conducting close contact screening in this study and $1,203,953.05 in the socioeconomic value. Each dollar generated $19.18 in socioeconomic benefits.
Conclusions: A comprehensive package, involving funding and introducing new techniques needs to be developed to further optimize the screening strategies of close contacts, particular emphasis should be placed on those with bacteria-positive index cases or those with suspected TB symptoms during follow-up.
Construction of a predictive model for fear of fall in rehabilitating elderly stroke patients using a multi- layer perceptron neural network
Authors: Zhang Xinyu , Zhang Lei 
Published: October 2023

Abstract

Objective
To establish a predictive model using multi-layer perceptron (MLP) for fear of fall in elderly stroke patients during the rehabilitation period.
Methods
From June 2022 to February 2023,368 elderly patients with rehabilitation stroke were investigated by scales.Conduct univariate and multivariate analysis of the influencing factors for fear of fall, using multivariate Logistic regression and MLP to establish the prediction model and calculate the prediction accuracy of the two models.Predictive efficacy was assessed using the receiver operating characteristic (ROC) curve.
Results
The prediction accuracy of the multivariate Logistic regression model was 78.00% and the area under the ROC curve was 0.848; the prediction accuracy of the MLP model was 84.90% and the area under the ROC curve was 0.890.
Conclusion
The prediction of fear of fall in elderly stroke patients during the rehabilitation period can be done with MLP model.
Mass Spectra Prediction with Structural Motif-based Graph Neural Networks
Authors: Jo Jeonghee , Park Jiwon , Yoon Sungroh 
Published: October 2023

Abstract
Mass spectra, which are agglomerations of ionized fragments from targeted molecules, play a crucial role across various fields for the identification of molecular structures. A prevalent analysis method involves spectral library searches, where unknown spectra are cross-referenced with a database. The effectiveness of such search-based approaches, however, is restricted by the scope of the existing mass spectra database, underscoring the need to expand the database via mass spectra prediction. In this research, we propose the Motif-based Mass Spectrum prediction Network (MoMS-Net), a GNN-based architecture to predict the mass spectra pattern utilizing the structural motif information of the molecule. MoMS-Net considers both a molecule and its substructures as a graph form, which facilitates the incorporation of long-range dependencies while using less memory compared to the graph transformer model. We evaluated our model over various types of mass spectra and showed the validity and superiority over the conventional models.
Influence of prenatal aquatic activities on fetal outcomes and maternal physical and mental outcomes: a systematic review and meta-analysis
Authors: Xu Junmiao , Chen Rongrong , Wang Yuhan , Zhao Kun , Zhou Feifei 
Published: October 2023

Abstract

Purpose
Aquatic activities are becoming increasingly popular as a form of exercise during pregnancy. However, the effects of these activities on the physical and mental health outcomes of pregnant women during and after pregnancy as well as fetal outcomes remain unclear. This meta-analysis evaluated the current evidence regarding the effects of aquatic activities during pregnancy on neonatal and maternal outcomes.
Methods
Three databases (PubMed, Cochrane, Embase) were searched from inception to March 7, 2023 for randomized controlled trials (RCTs) comparing the effects of aquatic activities versus standard prenatal care or no exercise on neonatal and maternal outcomes. Pooled outcome measures were determined using random-effects models.
Results
Ten RCTs including 1949 patients met the criteria for inclusion in this meta-analysis. The results showed that prenatal aquatic activities could significantly improve maternal weight control (mean difference [MD]= -0.91, 95% confidence interval [CI]= -1.64 to -0.18, P = 0.01, I2 = 0.00%), improve maternal quality of life (standard mean difference [SMD] = 0.16, 95%CI = 0.03 to 0.28, P = 0.01, I2 = 0.00%), and extend fetal birth length (MD = 0.48, 95%CI = 0.10 to 0.87, P = 0.01, I2 = 0.00%) compared with standard prenatal care or no exercise, while no significant differences were observed in fetal birth weight, Apgar score at 1 minute, Apgar score at 5 minutes, pH of umbilical cord blood, gestational age, rate of preterm delivery, incidence of postnatal depression and mode of delivery.
Conclusions
Prenatal aquatic activities can significantly improve maternal weight control and quality of life during pregnancy, and may promote longer birth length. However, additional studies are needed to confirm these findings.
Asbestos Ban Policies and Mesothelioma Mortality in Greece
Authors: Gogou Evdoxia , Hatzoglou Chryssi , Siachpazidou Dimitra , Zarogiannis Sotirios G. , Gourgoulianis Konstantinos I. 
Published: October 2023

Abstract

Background
Malignant mesothelioma is a rare form of cancer that mostly affects the pleura and has a strong link to asbestos exposure. Greece banned the use of asbestos in 2005, however, the public was already aware of this substance in the 1980s. This research aims to present an overview of Greece's mesothelioma mortality rates (MMR) from 1983 to 2019 by age, gender, and geographic region and to determine whether the actions to ban asbestos impacted these rates.
Methods
Data were retrieved by the Hellenic Statistical Authority (HAS) from death certificates that mentioned mesothelioma as the cause of death from 1983 to 2019 with details on the residence, gender, and age. Statistical analysis was performed using SPSS 29 software, a one-way ANOVA test followed by post-hoc and Dunnett C test for multiple comparisons or Independent samples T-test for comparison between two subjects.
Results
Males' MMR and the whole population's MMR reached their highest levels in 2011 (0.86/100000 and 0.52/100000, respectively). In order to look for any potential changes between the first two decades of the 21st century, we compared the mean MMR of each geographic region in Greece between two different 10-year subperiods (2000–2009 and 2010–2019). Except for Epirus, all regions of Greece had elevated regional MMRs, particularly in those with the highest asbestos deposits. Notably, the MMR in Epirus decreased from 0.55/100000 (2000–2009) to 0.38/100000 (2010–2019). After 2011, the MMR for men and the general population stabilized. This stability is important since mesothelioma in men is associated with occupational asbestos exposure. The intriguing discovery of a lower MMR in Epirus emphasizes the need to raise awareness of the condition and implement effective public health measures.
Conclusions
In Greece, the annual rate for males and the whole population reached its highest level in 2011, which is positive and encouraging and may be a sign that the rate will stabilize during the following years. Moreover, this study showed that the actions made in the 1980s regarding public awareness and surveillance directly impacted the decrease in Epirus rates. Future research, continual awareness, information, and recording are needed to monitor the mesothelioma epidemic.
Trial registration:
Not applicable
De novo 7q11.21 duplication with 4-hydroxy phenylacetic aciduria– A rare neurodevelopmental syndrome: A Case report
Authors: Akter Sanjida , Hossain Md Shafayat , Tasnim Fariha , Bulbul Mohammad Farhad , Ananna Farzana Rashni 
Published: October 2023

Abstract

Introduction The rearrangement of chromosomal genes, particularly duplication and deletion, is mostly known as a chromosomal disorder. Chromosome 7 has approximately 1.5 million base pairs (Mb); chromosome 7q11.21 region is prone to chromosomal rearrangement. Duplication in any of these regions can cause autism spectrum disorder. Organic acid disorder is when the body's metabolism does not function properly, producing insufficient energy and accumulating harmful substances in the blood and urine. 4-hydroxy phenylacetic acid is a metabolite of the methyl hydrogens substitution, which causes Schizophrenia, ulcerative colitis, and epilepsy. Method We performed Chromosomal microarray analysis (CMA) for the detection of chromosomal duplication from GC lab South Korea on peripheral blood samples and Liquid chromatography-tandem mass spectrometry (LS-MS/MS) for organic acid disorder on urine sample in our patient from Kyungpook National University Chilgok Hospital (Daegu, South Korea). We have reviewed both disorders' clinical features and genotype-phenotype characteristics. Psychological and behavioral modification, dietary modification, and supplementation are being applied appropriately. Result We have identified our patient with 4-hydroxyphenyl acetic aciduria by Liquid chromatography-tandem mass spectrometry (LS-MS/MS), and its concentration was found 84.4 (mmol/mol Cr) and duplication in chromosome 7q11.21 by CMA, which is 444 kb in size likely benign. Discussion We have found various autistic features related to chromosome 7q11.21 duplication and 4-hydroxyphenyl acetic aciduria. Timely treatment, proper diet, special behavioral care, and close monitoring may help improve the patient's condition.
Site quality for Araucaria angustifolia plantations with subtropical Cambisol is driven by soil organism assemblage and the litter and soil compartments
Authors: Souza Tancredo , Dobner Mário , Nascimento Gislaine dos Santos , Silva Lucas Jónatan Rodrigues da 
Published: October 2023

Abstract
Soil quality is a driver for biodiversity enrichment, soil fertility, and soil organic matter dynamics. Different soil quality levels at Araucaria angustifolia plantations may influence the soil organisms, and the interaction between litter and soil compartments by providing habitat and nutrients in different pathways. Our aim was to present a deeper view of the litter-soil compartments, and soil organisms community composition associated with three degrees of site quality (low-, average-, and high-quality sites), which reflect productivity levels, at the highlands of southern Brazil. The non-metric multidimensional scaling (NMDS) grouped the influence of soil quality degrees in three groups considering the dissimilarities on the soil organisms among each other. The ordination of the soil organisms, richness, and Shannon’s diversity in each studied soil quality degree had a stress value of 0.08. The structural equation models indicated that the loss of soil quality showed a negative relationship among soil organisms’ assemblage, and soil-litter compartments. Our results highlighted the importance of considering soil biotic and abiotic attributes for achieving high productivity levels from A. angustifolia plantations within its natural occurrence range.
Kiwifruit-A.blazei intercropping effectively improved yield productivity, nutrient uptake, and rhizospheric bacterial community
Authors: Shen Chuan , Li Xia , Qin Jianfeng 
Published: October 2023

Abstract
Background
Intercropping systems have garnered attention as a sustainable agricultural approach for efficient land usage, increased ecological diversity in farmland, and enhanced crop yields. This study examined the impact of intercropping on the kiwifruit rhizosphere to gain a deeper understanding of the relationships between cover plants and kiwifruit in this sustainable agricultural system.
Results
The analysis of soil physicochemical properties and bacterial communities was conducted in the Kiwifruit-A. blazei intercropping system. Moreover, the combined analysis of 16S rRNA gene sequencing and metabolomic sequencing was used to identify differential microbes and metabolites in the rhizosphere. Intercropping led to an increase in soil physicochemical (ALN, TN, SOC, AP, MBC, MBN) and enzyme activity (URE, NR), as well as re-shaped the bacterial community and increased in microbial diversity. Specifically, Proteobacteria, Bacteroidota, Myxococcota, and Patescibacteria were the most abundant and diverse phyla in the intercropping system. The expression analysis further revealed that the bacterial genera of BIrii41, Acidibacter, and Altererythrobacter were significantly upregulated in the intercropping system. Moreover, a total of 358 differential metabolites (DMs) were identified between the monocropping and intercropping cultivation patterns, with fatty acyls, carboxylic acids and derivatives, and organooxygen compounds being significantly upregulated in the intercropping system. The KEGG metabolic pathways further revealed the considerable enrichment of DMs in ABC transports, histidine metabolism, and pyrimidine metabolism. This study identified a significant correlation between 95 bacterial genera and 79 soil metabolites, and an interactive network was constructed to explore the relationships between these differential microbes and metabolites in the rhizosphere.
Conclusions
This study demonstrates that Kiwifruit-A. blazei intercropping can be an effective, labor-saving, economic, and sustainable practice for reshaping the bacterial community and promoting the accumulation and metabolism of beneficial microorganisms in the rhizosphere.
Technology-enabled great leap in deciphering plant genomes
Authors: Fan Longjiang , Gong Xiaojiao , Xie Lingjuan , Yang Kun , Shen Leti , Huang Yujie , Zhang Shiyu , Sun Yanqing , Wu Dongya , Ye Chuyu , Zhu Qian-Hao 
Published: October 2023

Abstract
Plant genomes provide essential and vital basic resources to study multifarious aspects of plant biology and applications (e.g. breeding). From 2000 to 2020, 1,031 genomes of 788 plant species were sequenced. From 2021 to 2023, 1,857 genomes of 841 plant species, including 622 newly sequenced species, were assembled, showing a great leap. The 1,857 newly assembled genomes, with some being telomere-to-telomere (T2T) assembles, cover the major phylogenetic clades and many of them have a high quality. The achievement is mainly attributed to significant advances in both sequencing technologies and assembly software. A database named N3: plants, genomes, technologies was developed to accommodate the metadata associated with the sequenced plant genomes. In the end, we discussed the challenges involved in building huge size gap-free and single-cell genomes as well as the future opportunities in plant genomic studies.
Prediction of isometric forces from combined epidural spinal cord and neuromuscular electrical stimulation in the rat lower limb
Authors: Song Daniel , Tresch Matthew 
Published: October 2023

Abstract

Both epidural spinal cord and muscle stimulation have been widely used for restoration of movement after spinal cord injury. However, using both approaches simultaneously could provide more flexible control compared to using either approach alone. We evaluate whether responses evoked by combined spinal and muscle stimulation can be predicted by the linear summation of responses produced by each individually. Should this be true, it would simplify the prediction of co-stimulation responses and the development of control schemes for spinal cord injury rehabilitation. In anesthetized rats, we measured hindlimb isometric forces in response to spinal and muscle stimulation across a range of amplitudes. Force prediction errors were calculated as the difference between predicted co-stimulation vectors and observed co-stimulation vectors whereby small errors signified evidence for linear summation. We found that the errors for spinal and muscle co-stimulation were significantly larger than expected. Using a bootstrapping analysis, we find that these larger errors do not reflect a nonlinear interaction between spinal and muscle responses. Instead, they can be attributed to the variability of spinal stimulation responses. We discuss the implications of these results to the use of combined muscle and spinal stimulation for the restoration of movement following spinal cord injury.