bluuebunny/crossref_metadata_2025_split huggingface dataset:
Forecasting VaR and ES by using deep quantile regression, GANs-based scenario generation, and heterogeneous market hypothesis
Authors: Wang Jianzhou , Wang Shuai , Lv Mengzheng , Jiang He 
Published: January 2024

AbstractValue at risk (VaR) and expected shortfall (ES) have emerged as standard measures for detecting the market risk of financial assets and play essential roles in investment decisions, external regulations, and risk capital allocation. However, existing VaR estimation approaches fail to accurately reflect downside risks, and the ES estimation technique is quite limited owing to its challenging implementation. This causes financial institutions to overestimate or underestimate investment risk and finally leads to the inefficient allocation of financial resources. The main purpose of this study is to use machine learning to improve the accuracy of VaR estimation and provide an effective tool for ES estimation. Specifically, this study proposes a VaR estimator by combining quantile regression with “Mogrifier” recurrent neural networks to capture the “long memory” and “clustering” properties of financial assets; while for estimating ES, this study directly models the quantile of assets and employs generative adversarial networks to generate future tail risk scenarios. In addition to the typical properties of financial assets, the model design is also consistent with heterogeneous market theory. An empirical application to four major global stock indices shows that our model is superior to other existing models.
Salmon processing discards: a potential source of bioactive peptides – a review
Authors: Ramakrishnan Vegneshwaran Vasudevan , Hossain Abul , Dave Deepika , Shahidi Fereidoon 
Published: January 2024

AbstractSalmon aquaculture generates 80% of the total revenue of finfish aquaculture across Canada. Salmon farming is carried out in a multilevel process, and at least 60% of the total production is considered as by-products, including skin, head, viscera, trimmings, frames, bones, and roes. These by-products are an excellent source of protein, which can be converted to protein hydrolysates through enzymatic hydrolysis and non-enzymatic processes such as chemical hydrolysis (acid and alkaline) in order to utilize them into value-added products. Several studies have reported that peptides from salmon protein hydrolysates possess bioactivities, including antihypertensive, antioxidant, anticancer, antimicrobial, antidiabetic, anti-allergic, and cholesterol-lowering effects. Incorporating in silico computational methods is gaining more attention to identify potential peptides from source proteins. The in silico methods can be used to predict the properties of the peptides and thereby predetermine the processing, isolation, and purification steps that can be used for the peptides of interest. Therefore, it is essential to implement robust, standardized, and cost-effective processing techniques that can easily be transferrable and scale up for industrial applications in view of circular economy and upcycling concept. This contribution summarizes the latest research information on Atlantic salmon, production statistics, growth lifecycle, processing, protein production techniques, nutritional and functional properties, peptide production and purification processes, as well as potential health benefits as a nutraceutical product.
Graphical Abstract
Changes in histone lysine acetylation, but not DNA methylation during facultative hibernation in Syrian hamster liver
Authors: Oosterhof Marloes M. , Coussement Louis , van Pijkeren Alienke , Kwiatkowski Marcel , Zwinderman Martijn R. H. , Dekker Frank J. , de Meyer Tim , Reitsema Vera A. , Bischoff Rainer , Guryev Victor , Bouma Hjalmar R. , Henning Rob H. , Rots Marianne G. 
Published: January 2024

Abstract
Background
Hibernation (torpor) is a strategy to survive extreme environmental conditions, associated with a significant decrease in metabolism and body temperature. The inducibility by the environment of torpor for facultative hibernators designates epigenetic mechanisms as likely candidates for regulation. Therefore, we set out to unravel epigenetics in the liver of a facultative hibernator, Syrian hamster (Mesocricetus auratus), sampled at different phases during hibernation, by assessing the expression of epigenetic writer and eraser enzymes, histone acetylation dynamics, and DNA methylation levels.

Results
Expression of epigenetic writers/erasers confirmed previously reported results obtained in obligatory hibernators, but might point to a mechanism specific for facultative hibernators, e.g., differential expression of histone acetyltransferases (HATs; KAT6A, KAT6B, KAT7, and KAT13D/CLOCK). These findings were in accordance with observed changes in histone H3 and H4 acetylation changes. Overall histone deacetylase (HDAC) activity was highest in torpor. No differences were detected in DNA methylation throughout all phases.

Conclusion
Our study thus points to histone acetylation as an important player in facultative hamster hibernation, which may underlie the orchestration of gene expression changes throughout hibernation.
Βιβλιογραφικά
Authors: Melianos Ioannis M. 
Published: January 2024

Additions, Supplements and Corrections to the Greek Bibliography (17th-19th Centuries)
The aim of this article, which presents some titles of old printed books, is to offer additions, supplements, and corrections to the Greek Bibliography (17th-19th centuries).The list of these titles is based mainly on the book collection of the convent of Zoodochos Pigi in Chora, Patmos, which has been recently inventoried. Furthermore, it is supplemented by a number of entries from the library of the Monastery of Saint John the Theologian.From these forty-eight entries, the first six concern uncatalogued editions –hence they are additions to the Greek Bibliography (one is an 18th century-edition, while the rest five date from the second half of the 19th century). As for the remaining forty-two entries, they are additions, corrections and remarks on editions known in the bibliography (17th-19th centuries).The entries concerning the uncatalogued editions are presented in full, while those of already known publications are presented in an abbreviated form, with the exception of those cases where the titles have been incorrectly catalogued. All entries include the precise number of folios or pages, and, when necessary, they present a detailed description of the contents, as well as further information. For all the cases in hand research and cross-checking have been conducted in the known printed bibliographies, as well as in the up-to-date electronic catalogue of the Greek Bibliography of the 19th century, provided by the Bibliology Workshop “Philippos Iliou”.
Το βυζαντινό αρχείο της μονής Πάτμου στα μέσα του 18ου αιώνα
Authors: Gerolymatou Maria 
Published: January 2024

L’archive byzantine de Saint Jean le Théologien de Patmos au milieu du XVIIIe siècle
L’archive byzantine du monastère de Saint Jean le Théologien de Patmos est une de mieux conservées archives byzantines. Au XVIIIe siècle Patmos fut un centre important d’éducation et de culture. Pendant cette période les moines s’occupèrent de la conservation et du classement des documents de l’époque byzantine, afin de préserver le patrimoine du monastère. Dans ce cadre, ils ont dressé des catalogues. Nous éditons ici un catalogue qui date de 1740. Le catalogue commence avec le(s) testament(s) de saint Christodoulos et continue avec des documents impériaux, des actes de fonctionnaires et des actes patriarcaux. Le critère du classement est plutôt thématique. Dans cet article, nous essayons d’identifier les documents mentionnés dans le catalogue à des documents qui sont conservés jusqu’à nos jours, tâche qui n’est pas facile, vu que les renseignements fournis sont souvent vagues. La question qui se pose est de savoir si l’auteur du catalogue avait à sa disposition des documents latents aujourd’hui. Cela semble avoir été le cas, au moins pour les documents ayant affaire à la fortune du monastère en dehors de Patmos. Il est également probable que l’auteur ait tenu compte des originaux d’actes que nous connaissons seulement par des copies. L’identité de l’auteur est malheureusement inconnue. Il semble que le catalogue était l’æuvre d’un moine lettré qui avait accès à la bibliothèque. L’écriture présente des similarités avec l’écriture du moine Athanasios Chrysochοou qui a vécu dans la première moitié du XVIIIe siècle et fut mort en 1763. Il est connu pour son activité de copiste et de relieur. En plus, il a été ecclésiarque, dignité qui lui permettait d’avoir accès à la bibliothèque du monastère. Sans prétendre proposer une réponse définitive, il n’est pas impossible qu’Athanase soit l’auteur du catalogue.
Διαφωτισμός και επανάσταση
Authors: Kitromilides Paschalis M. 
Published: January 2024

Enlightenment and Revolution. The interconnection of two historiographical terms in their multiple contexts
This brief essay attempts to address in an exploratory way a challenging question concerning the interconnection of two controversial historiographical terms, Enlightenment and Revolution. The term Enlightenment is defined on the basis of Immanuel Kant’s classic discussion in his 1784 essay and the multiple uses and understandings of the term and idea of Enlightenment are followed through their subsequent transformations in the milestones of relevant historiography. The term Revolution and its changing meanings are also traced in the sources from Herodotus and Thucydides to the discussion of the «Age of Revolution».The unending controversies over the possible causal interconnection of the broad phenomena denoted by the two terms are acknowledged, but it is suggested that the whole issue might be more effectively clarified if considered in specific historical contexts, by reference to which questions of evidence and historiographical interpretation might be more practically controlled and appraised. It is further suggested that the consideration of the relevant issues in the historical context of Southeastern Europe offers a realistic possibility for an informed judgement on the broader theoretical question on the basis of the evidence of the concrete historicalexperience of the region. This kind of contextualization in turn may provide correctives to the occasional excesses of theoretical debates.
Ασημάκης και Ανδρέας Ζαΐμης στη μυστική Συνέλευση της Βοστίτσας
Authors: Panayotopoulos Vassilis 
Published: January 2024

Assimakis et Andréas Zaimis à l’assemblée secrète de Vostitsa. Retournements révolutionnaires en janvier 1821
Du 26 au 29 janvier 1821, une assemblée secrète du Comité dirigeant de la Société des Amis (Philiki Hétairia) du Péloponnèse a été convoquée à Vostitsa (Aigion). L’Archimandrite Grigorios Dikaios (Papaflessas) y était présent, en tant que « représentant du Commissaire en chef de l’Autorité Suprême » de l’Hetairie, chargé, depuis l’année précédente, de l’organisation et de la direction du soulèvement au Péloponnèse. Les membres du Comité exécutif de l’Hetairie à Patras ont également participé à l’assemblée, ainsi qu’un certain nombre de primats des communes des vilaets de Patras, Vostitsa et Kalavryta, sélectionnés sans critère bien précis. En tout cas il s’agissait de membres initiés de l’Hétairie, de personnes plutôt proches au groupe local dominant de celle-ci. L’Assembléede Vostitsa est considérée par l’historiographie de la Révolution Hellénique comme le lieu du conflit entre le révolutionnaire ardent qu’était l’Archimandrite Papaflessas et l’Evêque de Patras Germanos, chef du Comité de l’Hétairie au Péloponnèse, qui hésitait et revendiquait de meilleures conditions matérielles pour l’organisation du soulèvement et la déclaration, sans équivoque, du soutien politique de la Russie. Cependant, et malgré cette discorde fondamentale, l’Assemblée de Vostitsa a abouti, apparemment, à un compromis nébuleux mais qui, pour l’essentiel, impliquait la décision d’entamer le Combat conformément aux plans del’Hétairie et même à la date du 25 mars 1821, déjà fixée. La suite des évènements révolutionnaires confirme l’hypothèse d’un aboutissement consensuel de l’Assemblée de Vostitsa et l’auteur de cette étude décèle les deux personnes, à savoir Andréas Zaimis et son ami intime Andréas Londos, qui ont été les facteurs principaux du changement des esprits au sein de l’Assemblée, de la neutralisation des oppositions et des hésitations, et du fait que l’esprit de la révolte a finalement prévalu. Sur le plan individuel, tous les deux émergent de cette étude comme récepteurs des messages des Lumières Grecques, mais aussi en tant que personnes qui manifestent une disponibilité liée à leur jeune âge et à l’enthousiasme provoqué au cours des travaux de l’Assemblée de Vostitsa par l’ardeur et l’éloquence de Papaflessas. On ne peut pas affirmer qu’il s’agit là d’une manifestation du conflit de générations typique des élites provinciales du système communal de l’Empire Ottoman ; cependant, si on la met en relation avec d’autres phénomènes analogues de radicalisme de l’époque, cette disponibilité démontre la multitude des courants d’idées qui travaillaientla société hellénique émergeante.
Ο Μάρκος Ρενιέρης και ο Spectateur de l'Orient
Authors: Argyropoulos Roxane D. 
Published: January 2024

Marco Renieri et le Spectateur de l'Orient. Ses opinions sur l’hellénisme
Marco Renieri (Trieste 1815-Athènes 1897), éduqué à Venise, subit l’ascendant du Risorgimento italien. Installé définitivement en 1835 à Athènes il se familiarise avec l’idéologie du nouvel État. Lors du déclenchement de la guerre de Crimée en 1853, un groupe d’intellectuels grecs, hostiles à une politique favorable à la Russie, s’empressent de faire paraître la revue Le Spectateur de l’Orient dont M. Renieri sera le rédacteur en chef. Leur but était de renforcer les liens avec l’Οccident qui risquaient en ce moment de se détériorer. Renieri traite des particularités de la société grecque et pense qu’au cours de la domination ottomane la religion a sauvé l’hellénisme et que l’organisation communale prépara le cadre institutionnel pour l’indépendence nationale. Il est préoccupé par la question du grec moderne en tant que moyen linguistique international,ce qui le rattache à G. d’Eichthal et à bien d’autres philologues français, allemands et anglais de son époque. À travers le prisme de son opposition aux interventions étrangères dans la politique de son pays, il met en avant le personnage du patriarche Cyrille Loukaris dans une pièce de théâtre intitulée « La jeunesse de Lucari. Drame historique en cinq actes » etdans son étude « Cyrille Lucari, ou l’Église grecque pendant la guerre de trente ans ». Exprimant d’une part son penchant pour les idées libérales de l’Occident et d’autre part son inquiétude pour l’epanouissement du slavisme, Renieri se prononce pour la neutralité de la Grèce. Il s’oriente vers une théorie centrée sur la reconnaissance de la position avantageuse de l’hellénisme moderne dans l’établissement d’un équilibre permettant la compossibilité entre la tradition culturelle et politique de l’Occident, à laquelle l’hellénisme appartient, et la Russie sa coreligionnaire.
Ο εκδότης Ν. Π. Ιγγλέσης και το περιοδικό Εύα (1923-1924)
Authors: Delveroudi Elisa Anna 
Published: January 2024

Publisher N. P. Inglessis and the magazine Eva (1923-1924)
Publisher of one French and five Greek-language publications, daily and weekly, during the 1920s, N. P. Inglessis has remained to this day a rather invisible case in the history of the Greek Press. Born in the late 1870s in Constantinople, he studied at the Chalki School of Commerce, and probably in London, and worked as an employee and then manager of the Bank of Athens before turning to publishing. My research in the Historical Archive of the National Bank of Greece provided biographicaland financial material, which allows us to assume the origin of the funds that supported the turn in his professional life. His publications were short-lived, but pioneering and insightful, seeking to fill thematic gaps, and reach the interested audiences. His popular magazine Eva, presented in more detail here, addressed a large number of women readers and often popularized positions of the women’s movement, especially those related to work, spreading them to wider and lower social strata, whocould not access the original collectives and theoretical discourses. Eva has probably worked as a model for similar publications, which circulated the following years in Greece. Accordingly, Inglessis’ Kinimatografos/Cinema, the first Greek magazine of its kind, dedicated to film, had also a clearly targeted readership, as well as his last and final attempt, Athlitika Chronika/Athletic Chronicles. Interestingly, N. P. Inglessis was the father of the first Greek film critic Iris Skaravaiou, indicating a path through which women could enter the journalist profession.
RELATIONSHIP OF INTERNET ADDICTION WITH HEADACHES IN ADOLESCENTS: COMORBID PATHOLOGY AND COMMON RISK FACTORS
Authors: Shubina Margarita V. , Tereshchenko Sergey Yu. , Moskalenko Olga L. , Kasparov Eduard V. 
Published: January 2024

Data on the relationship of headaches with Internet addiction is rather inconsistent.
Purpose: to establish common risk factors for the development of various types of Internet addiction and primary types of headache.
Materials and methods. 5195 schoolchildren aged 11-18 in Siberia were examined. Internet addiction and its types were determined using the Chen questionnaire, Game Addiction Scale and The Social Media Disorder Scale; Type of headache (migraine or tension headache) – according to the questionnaire of S.Yu. Tereshchenko, based on The International Classification of Headache Disorders, 3rd edition (beta version), 2013; Mental disorders – in computerized testing in the program “The Development and Well-Being Assessment” (DAWBA, R. Goodman et al.)
Results. It has been established that Internet addiction occurs 6 times more often in migraine and 3 times more often in tension headache. However, this relationship is only observed for Social Media Disorder. The connection of headaches with Game Addiction has not been revealed. At the same times headaches (especially migraine) and Internet addiction (predominantly social media disorder) have a common comorbid pathology and risk factors: recurrent abdomen pain, back pain, insomnia, daytime sleepiness, gastroesophageal reflux disease, asthenic syndrome, emotional problems, hyperactivity, high prognosis of mental pathology.
FEATURES OF METABOLISM AND THE POTENTIAL ROLE OF NEUROTROPHIC FACTORS OF THE BRAIN IN THE REHABILITATION PROCESS
Authors: Ageeva Elizaveta S. , Korsunskaya Larisa L. , Larina Natalia V. , Biryukova Elena A. , Chuprina Lyubov A. , Gurtovaya Anna K. , Orekhova Liliia S. 
Published: January 2024

Understanding the metabolic pathways of regulation and interaction of neurotrophic factors is interesting from the point of view of discussing neurotrophic factors as biological markers reflecting the dynamics and effectiveness of the rehabilitation process. The purpose was to analyze the features of production, metabolism, mechanisms of action of neurotrophic factors, which can explain the possibility of active involvement of the main neurotrophic factors in the rehabilitation process. The article presents an analysis of the literature on the metabolism of brain-derived neurotrophic factors (brain growth factor BDNF, neurotrophins NT-3 and NT4/5, fibroblast growth factor FGF-1 and FGF-2, nerve growth factor NGF, insulin-like growth factor IGF1, glial neurotrophic factor GDNF, ciliary neurotrophic factor CNTF). Information is given about the features of their production, the relationship between profactors and mature forms, as well as the specifics of interaction with receptors.
Conclusion. A statistically significant drop in the levels of neurotrophic factors during the rehabilitation therapy of children with cerebral palsy using the «exohand-2» software and hardware complex reflects the active involvement of neurotrophic factors in these processes. The spectrum of biological effects of neurotrophic factors allows us to consider the entire multicomponent mechanism that occurs in the brain in the process of functional restructuring as sufficient for rehabilitation recovery.
IMPROVEMENT OF APPROACHES TO ELIMINATION OF VIRUSES IN POTATOES USING IN VITRO CULTURE
Authors: Bychkova Olga V. , Brovko Elena S. , Mironenko Olga N. , Khlebova Lyubov P. , Nebylitsa Anastasia V. 
Published: January 2024

Background. Potatoes are considered to be easily susceptible to infections, including viral diseases, which is one of the reasons for the decrease in yield. To date, the only ways to obtain and reproduce healthy potato material are technologies based on meristem-tissue cultures.
Purpose. The aim of this study was to improve approaches to the release of potato from viral infection using in vitro culture.
Materials and methods. The objects were tubers, microplants and microtubers of six cultivars of potato affected by PVS, PVA, PVM, PVX and PVY viruses in various combinations. Viruses were eliminated from plant material by thermotherapy at a temperature of 38.0±0.5°C. Depending on the cultivar and object, the exposure was 10-25 days.
Results. The study showed that the use of potato microtubers as an object for thermotherapy makes it possible to release plant material from viruses in 25.0-50.0% of cases, depending on the pathogen. The advantage of this virus eradication scheme is, firstly, in the increase in the regenerative capacity of explants up to 32.9% due to the exclusion of the sterilization stage after thermotherapy and the absence of apical meristem culture as an additional method of sanitation. Secondly, the efficiency of the release of plant material from viruses increases due to a longer exposure to high temperature up to 25 days.
Conclusion. The use of this approach made it possible to eliminate not only individual viruses, but also their complex, for example, PVA + PVX, PVM + PVX, PVX + PVS, PVM + PVX + PVS.
Impact of heliotherapy and phototherapy on the course of atopic dermatitis
Authors: Mańkowska Aleksandra , Truchta Monika , Kolano Agata , Jabłońska Wiktoria , Wardęszkiewicz Marta , Kasprzak Amelia , Markowiak Szymon , Świercz Maciej , Pejas Anna 
Published: January 2024

Introduction and purpose. Atopic dermatitis (AD) is a common chronic inflammatory skin disease that affects many children and adults around the world. It has been also empirically known that some environmental factors such as exposure to the sun can be beneficial for patients with AD. The purpose of this literature review is to present positive impact, as well as challenges and risks of heliotherapy and phototherapy on patients suffering from AD.
Material and methods. The article is a review of publications obtained from the PubMed database and published between 2017-2023. Based on the keywords "phototherapy" "heliotherapy"and "atopic dermatitis", 14 articles were selected. Finally, 1 meta-analysis and 3 observational studies were included in the rewiev.
Brief description of the state of knowledge. People with AD have a compromised skin barrier, which favors infiltration by activated Th2 cells, and their cytokine, causing thickening of the skin. It makes management of AD challenging. It is known that most patients’ skin condition improves due to sun exposure. This is why an artificial UV radiation (UVR) is employed for the treatment. The idea is to administrate a non-ionizing radiation to the skin. Both sunlight and artificial light have a significant immunosuppressive effect on the skin.
Summary. Phototherapy as well as heliotherapy improved skin condition of people suffering from AD. It was appreciable by the end of few weeks of studies and also afer 3 months, reflected by improvement in PO-SCORAD, VAS and DLQI scales. During some of the studies there have been incidents of side-effects. More research is necessary to define a long-term effect of this kind of treatment and the role of chronic and prolonged therapy of AD.