bluuebunny/crossref_metadata_2025_split huggingface dataset:
Kronik yüzeyel femoral arter tıkanıklığında retrograd rekanalizasyon: Birincil strateji olarak güvenli ve etkili mi?
Authors: BUDAK Ali Baran , GÜNERTEM Eren , TÜMER Naim Boran , ÖZIŞIK Kanat , GÜNAYDIN Serdar 
Published: December 2023

Amaç: Periferik arter hastalığı (PAH), dünya çapında koroner arter hastalığı ve serebrovasküler olaylardan sonra en sık görülen mortalite ve morbidite nedenlerinden biridir. Kronik tıkalı yüzeyel femoral arter (SFA)’in endovasküler tedavisi (EVT) genellikle antegrad yaklaşımla yönetilir. Retrograd popliteal erişim (RPA), antegrad girişimin başarısız olduğu veya birincil seçenek olarak tercih edildiği durumlarda değerli bir seçenektir. Birinci basamak strateji olarak yüzüstü pozisyonda RPA'nın seçildiği ve rekanalizasyon için perkütanöz kasıtlı ekstralüminal anjiyoplasti (PIER) tekniğinin kullanıldığı hastaları, ileriye doğru girişimin başarısız olduğu ve sırtüstü pozisyonda RPA'nın kullanıldığı hastaları karşılaştırmayı amaçlıyoruz. 15 aylık takip ile rekanalizasyon için çift yönlü “randevous” tekniği kullanıldı.
Gereç ve yöntemler: Şubat 2017 ile Nisan 2019 arasında ardışık EVT'leri retrospektif olarak inceledik ve SFA lezyonlarının CTO'sunun rekanalizasyonu için RPA'nın kullanıldığı tüm EVT'leri seçtik. Çalışma, hastaları Grup 1 (n=24) olarak iki gruba ayırdı: Birinci basamak strateji olarak yüzüstü pozisyonda RPA'nın seçildiği ve rekanalizasyon için PIER tekniğinin kullanıldığı hastalar (6F Sheat ile) ve Grup 2 (n= 22): Antegrad girişimin başarısız olduğu ve endolüminal rekanalizasyon ile sırtüstü pozisyonda RPA'nın olduğu veya lezyonu geçerken telin başarısız olduğu hastalar, rekanalizasyon için çift yönlü “çift balon (randevu)” tekniği kullanıldı (Kılıfsız).
Bulgular: Teknik başarı oranı %100 oldu. RCC ve ABI her iki grupta da işlem sonrası anlamlı düzeyde iyileşti. Grup 1'de daha fazla hastaya primer stent gerekti (%70,8 vs. %45,4; p0,05). 1 yıllık uzuv kurtarma oranı her iki grup için de 100 ± 0 idi. Grup 2'de primer açıklık oranları grup 1'e göre daha yüksekti ancak bu fark ancak 6. ayda anlamlı hale geldi (grup 1'de sırasıyla %95,8, %87,5, %79,1'e karşı grup 2'de sırasıyla %100, %95,4, %81,8); p
Performance of Automatic Unpowerer Subsurface Irrigation on Water-Lettuce, Choy-Sum, and Spinach Cultivations
Authors: Syafriyandi Debby , Setiawan Budi Indra , Arif Chusnul , Suwardi Suwardi 
Published: December 2023

Irigasi bawah permukaan otomatis nirdaya yang dijadikan objek dalam penelitian ini ditujukan untuk memberikan air langsung ke zona perakaran dan akan berhenti bila sudah mencukupi dengan menggunakan katup level air. Penelitian ini bertujuan untuk mengevaluasi kinerja model irigasi ini pada 3 jenis sayuran, yaitu kangkung, Caisim, dan bayam dengan indikator produktivitas lahan, produktivitas air dan koefisien tanaman. Jaringan irigasi berupa rangkaian pot tanaman sejumlah 12 buah, masing-masing berukuran 33 cm diameter atas, 23.5 cm diameter bawah, dan tinggi 31 cm. Satu pot berukuran sama dijadikan pengendali level air. Air irigasi otomatis mengalir bila terjadi penurunan level air di setiap pot tanaman. Level air yang dipertahankan adalah 10 cm di bawah permukaan tanah. Diperoleh hasil, produktivitas lahan Caisim 9.6 kg m-2, bayam 12.3 kg m-2 dan kangkung 25.1 kg m-2. Produktivitas air Caisim 29.0 kg m-3, bayam 12.3 kg m-3, dan kangkung 52.4 kg m-3. Koefisien tanaman untuk Caisim berkisar 0.12–1.71, bayam 0.12–0.94, dan kangkung 0.16–1.46. Dapat disimpulkan, model irigasi bawah permukaan otomatis nirdaya ini sangat efektif dan efisien serta mudah dalam pemeliharaan dan pengoperasiannya.
Insights into the behavior and kinetics of purun tikus degradation during slow pyrolysis
Authors: Farobie Obie , Amrullah Apip 
Published: December 2023

Purun tikus (Elocharis dulcis), a type of wetland biomass feedstock, is a challenge to the swamp ecosystem as it contributes to pollution in the area. Hence, integrating the use of purun tikus as a source of bioenergy, particularly in the form of bio-oil, is of the highest priority. Nevertheless, there is a lack of research on the degradation rate of purun tikus conversion to bio-oil through pyrolysis. Thus, this study aims to evaluate the rate of destruction of purun tikus in the process of conversion into bio-oil via pyrolysis. In the experiment, a batch reaction vessel was used to carry out slow pyrolysis at temperatures ranging from 300 to 500 °C, and the reaction times ranged from 60 to 120 min. By assuming a first-order process and using the Arrhenius equation, it was possible to figure out the activation energy and the preexponential factort. To determine whether purun tikus destroyed during pyrolysis, an activation energy of 43.317 kJ mol-1 and a pre-exponential factor of 0.351 s-1 were identified.
Intervenciones no farmacológicas en la disminución del dolor postoperatorio en pacientes adultos de la unidad de recuperación postanestésica
Authors: Durand Morishigue Masako Alicia , Campos Coronel Hugo Rolando 
Published: December 2023

Objetivo: Analizar la producción bibliográfica disponible sobre las intervenciones no farmacológicas para la disminución del dolor postoperatorio en pacientes adultos de la unidad de recuperación postanestésica. Material y métodos: Se realizó una revisión bibliográfica en las bases de datos Scientific Electronic Library Online (SciELO), PubMed, Elsevier y Medigraphic, en inglés y español. En la elección se consideraron artículos originales y completos publicados entre los años 2013 y 2022, cuyas intervenciones no farmacológicas lo realicen enfermeros y otros profesionales de la salud durante la fase postoperatoria. Se excluyeron estudios de revisión bibliográfica y que presenten dificultad para acceder al documento completo. Resultaron aptos 30 artículos para la fase de análisis. Resultados: Las intervenciones no farmacológicas más frecuentes de forma global fueron los masajes (27 %), seguido de la musicoterapia (17 %) y la aromaterapia (17 %). En las intervenciones de tipo físicas, prevalecieron los masajes (62 %); en las de tipo psicosociales, psicoeducativas y cognitivo-conductuales, destacaron la musicoterapia y la aromaterapia (38 % cada una); y de tipo combinada, los masajes junto con la aromaterapia (50 %). Conclusiones: Se identificaron intervenciones físicas, psicosociales, psicoeducativas y cognitivo-conductuales, y la combinación de estas como propuestas no farmacológicas para disminuir el dolor, entre las que destacan los masajes del grupo de intervenciones físicas.
The Existence of Leptospira interrogans on Rats and The Transmission Potency in Public Areas: School, Traditional Market, and Settlement in Yogyakarta
Authors: Wibawaning Astuti Raden Roro Upiek Ngesti , Yuangga Salsabila Rifda , Fahrunniam  
Published: December 2023

Leptospirosis is a zoonotic disease caused by bacterial infection, Leptospira interrogans. Indonesia is known for being an endemic country of this disease and Yogyakarta Special Province has become one of the regions with high cases of Leptospirosis. There was lack of information on the L. interrogans prevalence on rats at the public areas, such as school and traditional market. This research was conducted to determine and predict the potential Leptospirosis transmission in public areas, especially in schools, traditional markets,. and the settlement of Yogyakarta. Wild rats were collected from several public places (elementary schools, traditional markets, and Settlement areas) by using single live traps. The rat's blood was centrifuged to obtain the serum. The serum was tested by using immunochromatography of Leptotek Lateral Flow. The collected rats and shrews were euthanized and then identified for the species and the morphological features. Total of 27 rats (67.5%) and shrews 13 (32.5%) were collected. There were six species of collected rats, namely Rattus argentiventer, Rattus norvegicus, Rattus tanezumi, Rattus tiomanicus, and Bandicota bengalensis, while the collected shrew species was Suncus murinus. The rats and shrews from traditional market were negative with L. interrogans, however the positive results was in elementary schools (14.28%), that were from R. norvegicus and S. murinus, moreover the positive infection also showed in the settlements (57.14%), that were from R. argentiventer, R. norvegicus, and R. tiomanicus. These findings indicated that school and settlement must be a concern for the leptospirosis transmission.
Nigella sativa 3% Inhibition Test of Nаturаl Toothpаste Compаred Cetylpyridinum chloride (CPC) Toothpаste 0.01-0.1% on Аggregаtibаcter actinomycetemcomitаns
Authors: Setiawatie Ernie Maduratna , Widiyanti Prihartini , Retno Puji Rahayu  , Eprilina Alifiani , Sandrasari Desi , Savitri Irma Yosephina , Bargowo Lambang , Rihandhita Shinta Meiliana  
Published: December 2023

Periodontitis generаlly begins with gingivitis progresses to alveolar bone increаsing the risk of systemic diseаse. The primаry etiologicаl fаctor in the etiology of periodontаl diseаse is Аggregаtibаcter аctinomycetemcomitаns bacteria. Cetylpyridinium chloride (CPC) has a bactericidal effect by disrupting the function of bacterial membranes in the cytoplasm. CPC can also absorb negative charges from bacteria, increase bacterial cell wall permeability, decrease cell metabolism, and reduce bacterial attachment to teeth. Use of аntimicrobiаl toothpаste, such as Cetylpyridinium chloride (CPC), is one strategy to prevent periodontаl disease, but CPC is hаzаrdous in some quаntities. Аs а result, it should be compared to a natural toothpaste, specifically Nigellа sаtivа toothpаste. The objective of this study is to compare the аntibаcteriаl аctivity of nаturаl toothpаste contаining Nigellа sаtivа 3% with toothpаste contаining CPC 0.01% - 0.1% on Аggregаtibаcter аctinomycetemcomitаns. Experimentаl studies are used in this kind of research. The colony count method wаs used to аssess the nаturаl toothpаstes Nigellа sаtivа 3% аnd toothpаste contаining CPC 0.01- 0.1% for their cаpаcity in inhibiting the Аggregаtibаcter аctinomycetemcomitаns. Natural toothpаste containing Nigellа sаtivа 3% wаs completely inhibiting Аggregаtibаcter аctinomycetemcomitаns, compared to 0.01-0.1% CPC toothpаste. The significаnce level for the stаtisticаl test results wаs 0.000 (p<0.05). The conclution of this research are the nаturаl toothpаste contаining Nigellа sаtivа 3% аnd toothpаste contаining CPC 0.06%–0.1% can effectively suppress the growth of the microorgаnisms Аggregаtibаcter аctinomycetemcomitаns.
Risk Factors Associated with Suspected Clostridium difficile Infection (CDI) in Elderly Diarrhea Patients at Prof. Dr. I.G.N.G. Ngoerah Hospital
Authors: Aryana I Gusti Putu Suka , Budayanti Ni Nyoman Sri , Wedari Ni Luh Putu Harta 
Published: December 2023

Clostridium difficile infection (CDI) is a typical healthcare-associated infection that contributes to a significant proportion of morbidity and mortality among hospitalized patients. Anaerobe microbiological laboratory examinations cannot be performed at Prof. Dr. I.G.N.G. Ngoerah Hospital, leading to many undetected cases; therefore, it is crucial to determine the risk factors. Identification of cases may help to prevent, recognize, and appropriately treat CDI, reducing morbidity and mortality. This study aimed to determine the risk factors associated with suspected CDI in elderly patients with diarrhea due to their vulnerability to immunosenescence. This research used medical records as secondary data to determine the risk factors associated with suspected CDI in elderly diarrhea patients at Prof. Dr. I.G.N.G. Ngoerah Hospital during the year period of 2017 to 2021 with total of 70 samples who met inclusion criteria by purposive sampling technique. One hundred percent of all samples had a history of hospitalization for ³ 48 h. There were 53 patients (77.1%) had a history of antibiotic use, 26 (37.1%) proton pump inhibitors (PPIs), 66 (94.3%) chemotherapy, 66 (94.3%) urinary tract infections, 6 (8.6%) kidney disease, and 7 (10%) myocardial infarction. Seven (10%) patients had vascular disease, and 11 (15.7%) had diabetes mellitus. Risk factors associated with suspected CDI in elderly patients with diarrhea at Prof. Dr. I.G.N.G. Ngoerah Hospital include hospitalization ³ for 48 hours, use of antibiotics in the last few months, proton pump inhibitors, decreased immune system, urinary tract infection, kidney disease, myocardial infarction, vascular disease, and diabetes mellitus.
Analysis of a crack with finite electrical permeability between two piezoelectric materials
Authors: Levchenko Maksym , Loboda Volodymyr 
Published: December 2023

A crack with finite electrical permeability between two piezoelectric materials is investigated. Initially, it is believed that the length of the crack is much smaller than the size of the body, so the latter is considered infinitely large. Assuming that the electric flux through the crack does not change along its length, an analytical solution to the given problem is constructed. On the base of this solution the magnitude of the electric flux, as well as other components of the electromechanical fields are found. A fairly simple formula for the energy release rate (EER) is also derived. For some values of the electrical permeability of the crack medium and external loads, the amount of electric flow through the crack and EER are calculated. Approbation of the obtained results was carried out on the example of a similar problem, but for the domain of finite dimensions. The finite element method (FEM) was used and the inverse approach was applied. According to this approach, the electric flux through the crack, which is obtained analytically, is used, and the solution is carried out using FEM. The analysis of the obtained numerical results confirmed the reliability of the methodology and the obtained analytical solution.
Keywords: crack with finite electrical permeability; piezoelectric bimaterial; analytical solution; finite element method.
Development of a software tool for remote control of knowledge
Authors: Kovtun Oleksandr , Linnyk Oleksii , Ivanchenko Kseniia 
Published: December 2023

The purpose of this study was to develop and implement an information system for evaluating and testing students' knowledge in order to simplify the process of creating tests and evaluating the educational achievements of teachers. In the course of the work, a review of existing computer training programs, an analysis of the market of modern analogues was carried out, and on the basis of the obtained data, functional and non-functional requirements for the developed software product were formulated. Based on the requirements, technical and software tools were chosen for the development of the program, namely the JavaScript programming language and the ReactJS framework for the development of the client part of the web application, which allows for quick and convenient development of interactive user interfaces and guarantees the stable operation of the system. The server part of the application is implemented using the powerful and flexible Spring framework, which allows you to create scalable and high-performance web applications.
To achieve the goal, the following tasks are solved in the work: registering a new user, editing user data, logging in and out of the system, viewing/creating/editing/deleting a study group, viewing students of a selected group, viewing/creating/editing/deleting/ publishing a test, viewing/creating/editing an exercise in a separate test, receiving all exercises in a selected test, assigning a test to a selected group, the ability to view/take tests assigned to the user (his group), the ability to check exercises and assign a grade (some exercises may be evaluated by the system automatically if the teacher gave the correct answer for comparison), the ability to view the result for the passed test. A MySQL database was designed and built according to the described data model that corresponds to the third degree of normalization. The structural and functional scheme of the system has been developed. There are three user roles: administrator, teacher, student. Great importance was attached to ensuring the simplicity and ease of use of the user's product, as this plays a key role in the use of the software. In the process of developing the program, great attention was paid to creating an intuitive and comfortable interface.
As a result, an information system for automated testing was created, which successfully fulfills the assigned tasks and meets all the specified requirements, and is also fully ready for practical implementation. The obtained results can be used both to integrate the program into the educational process and to provide students with the opportunity to acquire practical skills
Posterior Tibiotalar Impingement After Pediatric Ankle Fracture Surgical Fixation
Authors: Liu David S. , Watkins Ian T. , Adams Taylor , Kramer Dennis E. , Watkins Colyn J. 
Published: December 2023

Case:
A 13-year-old healthy, nearly skeletally mature, female patient presented to an outpatient clinic after sustaining a bimalleolar ankle fracture-dislocation, which was subsequently treated with open reduction and internal fixation and casting. Postoperatively, the patient had significant limitations to ankle range of motion. Imaging revealed posterior tibiotalar impingement. The patient underwent arthroscopic debridement and osteoplasty, and she was able to return to previous levels of activity.

Conclusions:
Complications from pediatric ankle fractures are rare, so further diagnostic workup is warranted for patients with persistent pain and limitations.
Exploration and Development of Shale Oil in China: State, Challenges, and Prospects
Authors: Jin Z. , Liang X. 
Published: December 2023

Abstract
—This article presents the latest state of exploration and development of shale oil of continental lacustrine formations in the main basins of China, summarizes the main theoretical considerations and key technologies for exploration and development, and suggests prospects for exploration and development of shale oil in China. It is believed that the exploration and development of oil in shale formations rich in organic matter of types I and II of medium and high maturity are key to the breakthrough of production of 10 million tons in China. This will play an important role in China’s stable oil production at the level of 200 million tons per year in the future. The efficient development of medium- and low- maturity shale oil resources can be significantly improved and lead to serious changes in oil production only after new breakthroughs in the theory and technology of shale deposits.
Distributed Multi-Agent Learning is More Effectively than Single-Agent
Authors: Ke Shuya , Liu Wenqi 
Published: December 2023

Abstract
This work has been submitted to the IEEE for possible publication. Copyright may be transferred without notice, after which this version may no longer be accessible. Interpretable distributed group intelligence techniques have emerged as an essential topic in artificial intelligence. The mathematical interpretability of prediction outcomes is critical for improving the reliability of machine learning, especially in random scenes. Although some experimental results published so far show that the prediction of group intelligence is better than individual intelligence, establishing a mathematical foundation for the superiority of distributed group intelligence is still a challenging problem for enhancing the interpretability of learning systems. Through the Radermacher complexity principle, we proved mathematically that the learning quality of group machine intelligence is better than its subset machine intelligence with a high probability, significantly better than any individual among them if the number of individuals in the group is large enough. We proposed a multi-agent distributed learning method for time series forecasting by incorporating multi-agent cooperation in cognitive processes into machine learning. In addition, since the way of cooperative interaction between multi-agent affects the training effect of the model, we provide a generalized interaction approach and prove its convergence. We conduct sufficient experiments on predicting time series for classically chaotic systems, and the results indicate that distributed group intelligence significantly improves the prediction accuracy of individual intelligence. The experiments result shows that the prediction error reduces substantially as the number of agents increases, confirming the theoretical accuracy and the model's validity. This work provides new ideas for theoretically exploring how group intelligence emerges.
Challenges to Diagnosis of SARS-CoV-2 Infection in the Nervous System
Authors: Silva Samya Jezine da , Cabral–Castro Mauro Jorge , Gonçalves Cássia A , Mariani Diana , Ferreira Orlando , Tanuri Amílcar , Puccioni-Sohler Marzia 
Published: December 2023

Abstract
The SARS-CoV-2 may invade the nervous system but it is rarely found in the cerebrospinal fluid (CSF). We evaluated the accuracy of real-time reverse transcription-polymerase chain reaction (real-time RT-PCR) for SARS-CoV-2 combined with specifics IgG and IgM, neopterin and CXCL-10 in 70 CSF from patients with neurological disorders associated or not with COVID-19. We found 57.1% sensitivity for IgG, 28.57% for IgM, 100% specificity for both tests, and higher protein and CXCL-10 in COVID-19 groups. No samples were positive for RT-PCR in CSF. Although the limited sensitivity, the reactive tests may still contribute to confirm the diagnosis of neurological complications associated with COVID-19.
HIF-1α participates in the regulation of S100A16-HRD1-GSK3β/CK1α pathway in renal hypoxia injury
Authors: Liang Xiubin , Han Shuying , Jin Runbing , Huo Lei , Zhao Lihua , Zhang Kaini , Li Rongfeng , Su Dongming 
Published: December 2023

Abstract

S100 calcium-binding protein 16 (S100A16) is implicated in both chronic kidney disease (CKD) and acute kidney injury (AKI). Previous research has shown that S100A16 contributes to AKI by facilitating the ubiquitylation and degradation of glycogen synthase kinase 3β (GSK3β) and casein kinase 1α (CK1α) through the activation of HMG-CoA reductase degradation protein 1 (HRD1). However, the mechanisms governing S100A16-induced HRD1 activation and the upregulation of S100A16 expression in renal injury are not fully understood. In this study, we observed elevated expression of Hypoxia-inducible Factor 1-alpha (HIF-1α) in the kidneys of mice subjected to ischemia-reperfusion injury (IRI). S100A16 deletion attenuated the increased HIF-1α expression induced by IRI. Using a S100A16 knockout rat renal tubular epithelial cell line (NRK-52E cells), we found that S100A16 knockout effectively mitigated apoptosis during hypoxic reoxygenation (H/R) and cell injury induced by TGF-β1. Our results revealed that H/R injuries increased both protein and mRNA levels of HIF-1α and HRD1 in renal tubular cells. S100A16 knockout reversed the expressions of HIF-1α and HRD1 under H/R conditions. Conversely, S100A16 overexpression in NRK-52E cells elevated HIF-1α and HRD1 levels. HIF-1α overexpression increased HRD1 and β-catenin while decreasing GSK-3β. HIF-1α inhibition restored HRD1 and β-catenin upregulation and GSK-3β downregulation by cellular H/R injury. Notably, Chromatin immunoprecipitation (ChIP) and luciferase reporter assays demonstrated HIF-1α binding signals on the HRD1 promoter, and luciferase reporter gene assays confirmed HIF-1α's transcriptional regulation of HRD1. Additionally, we identified Transcription Factor AP-2 Beta (TFAP2B) as the upregulator of S100A16. ChIP and luciferase reporter assays confirmed TFAP2B as a transcription factor for S100A16. In summary, this study identifies TFAP2B as the transcription factor for S100A16 and demonstrates HIF-1α regulation of HRD1 transcription within the S100A16-HRD1-GSK3β/CK1α pathway during renal hypoxia injury. These findings provide crucial insights into the molecular mechanisms of kidney injury, offering potential avenues for therapeutic intervention.