bluuebunny/crossref_metadata_2025_split huggingface dataset:
دور التجديد الاستراتيجي في إدارة أزمات قطاع الصناعات الدوائية اليمني
Authors: مفتاح محمد حسين علي , طواف عبدالخالق هادي محسن 
Published: January 2024

هدفت الدراسة إلى معرفة دور التجديد الاستراتيجي بأبعاده (الاستكشاف، استثمار الفرص، ريادة الأعمال، القيادة التشاركية، الفعل الاستراتيجي المنسق) في عملية إدارة أزمات قطاع الصناعات الدوائية اليمني، كما هدفت إلى التعرف إلى مستوى ممارسة التجديد الاستراتيجي وأبعاده، وكذا إدارة الأزمات وأبعادها في ذات القطاع، ولمحاولة كشف هذا الدور وتفسير هذه العلاقة، اعتمدت الدراسة على المنهج الكمي بأسلوبية التحليلي والوصفي، واستخدمت الدراسة أداة الاستبانة لجمع البيانات الميدانية من مجتمع الدراسة المتمثل في عشر شركات تمثل قطاع الصناعات الدوائية اليمني، بأسلوب الحصر الشامل للفئات الإدارية في هذه الشركات بعينة قدرها (415) مشاركًا، ولغرض تحليل البيانات والاستفادة منها استخدمنا برامج التحليل الإحصائي (Spss.26)، و(Amos.26)، وقد أظهرت نتائج الدراسة أن هناك مستوى عاليًا من ممارسة التجديد الاستراتيجي في القطاع الدوائي، بينما ممارسة إدارة الأزمات كانت بمستوى فوق المتوسط، وتوصلت الدراسة إلى أنه يوجد دور إيجابي معنوي للتجديد الاستراتيجي في إدارة أزمات قطاع الصناعات الدوائية، وأوصت الدراسة بعدة توصيات منها: أهمية اعتماد التجديد الاستراتيجي وزيادة الاهتمام بعملياته؛ لأنه ليس عملًا اعتياديا أو خطة روتينية بل هو اطاراً معرفيًا وإداريا للمنظمات للتغلب على التهديدات الخارجية والقيود الداخلية وفي الوقت نفسه تحسين الأداء، وكذا على الشركات المصنعة للأدوية العمل على كسر الجمود الاستراتيجي والبدء بالتجديد الاستراتيجي التدريجي مع الاستمرار في إنتاج أصناف جديدة، بالإضافة إلى ضرورة الاهتمام بممارسة إدارة الأزمات خصوصًا الاستراتيجية الوقائية.
Bone Marrow Aspiration Cytology in Diagnosing Hematological Disorder in a Tertiary Care Center
Authors: Kafle Neeta , Upadhaya Kafle Santosh , Singh Mrinalini , Sinha Amrita , Sedhain Sapana , Bhattarai Soorya 
Published: January 2024

Introduction: Bone marrow aspiration is a safe, simple and minimally invasive procedure used for evaluation of hematological disorder. It is useful when diagnosis from the first line investigations are inconclusive.
Objectives: To compare the clinical findings and bone marrow aspiration cytology findings
Methodology: This is a prospective hospital based cross sectional study carried out in Birat Medical College. Simple random consecutive sampling was done in patients that underwent bone marrow aspiration from December15th 2021 to June 14th 2022. Dry tap, patient under treatment and inadequate material were excluded from the study. After informed consent, BMA was done from the right or left posterior superior iliac crest using local anesthesia. Smeared slides were stained by Wright stain and was examined by two pathologists. Special stain was not done. Ethical clearance was taken from Institutional Review Committee (IRC). Data collected was then tabulated by using Microsoft Excel sheet and SPSS
Results: A total of 106 patients were included in this study with majority aged > 45 years (50.9%). The commonest indications for bone marrow aspiration was anemia under evaluation (35.9%) followed by pancytopenia under evaluation (22%). The most common diagnosis identified by bone marrow aspiration was mixed nutritional deficiency anemia (21.7%).In patients evaluated for pancytopenia six were diagnosed with hematological malignancy.
Conclusion: Nutritional deficiency anemia, commonly indicated for bone marrow aspiration, was the most common cause diagnosed by bone marrow aspiration. Bone marrow aspiration is important to arrive at diagnosis especially in patients with anemia and pancytopenia.
ANALISIS PELAYANAN BIDANG FARMASI MENGGUNAKAN INDIKATOR LAYANAN BERBASIS WHO: TINJAUAN SISTEMATIS
Authors: Akri Yusnita Julyarni 
Published: January 2024

Pharmaceutical services in hospitals are an inseparable part of the hospital's health service system that is oriented towards patient service, the provision of quality and affordable pharmaceutical preparations, medical devices, and consumables for all levels of society including clinical pharmacy services. The purpose of this study is to systematically review the implementation of pharmaceutical services based on WHO indicators. The articles used were selected from the Google Scholar journal database published from January 2013 to December 2023. Keywords for the study included "service" or "pharmaceutical" or "pharmacy" or "indicator" or "hospital" or "WHO". A total of 476 articles were generated from the initial search, the author identified 8 articles on pharmaceutical services based on WHO indicators. Based on a systematic review, most hospitals have implemented pharmaceutical services based on WHO indicators. Based on a systematic review, the implementation of pharmaceutical services in accordance with WHO standards is the selection stage: conformity with the hospital formulary; procurement: frequency of procurement of each drug item annually and on an EOQ basis; distribution: the degree of availability of the drug; Usage: percentage of generic prescriptions, percentage of drugs delivered, percentage of drugs labeled complete and average time spent serving prescriptions.
Le football féminin dans les quartiers défavorisés au Maroc
Authors: Benkorti Aziz 
Published: January 2024

Des aspects socioculturels (socialisation familiale, perception dominante du corps féminin, espaces genrés) contribuent à l’explication du faible taux de pratique sportive des femmes marocaines, notamment dans certains sports considérés comme « masculins ». À partir d’une enquête qualitative réalisée auprès d’un groupe de jeunes footballeuses âgées de 14 à 20 ans, de leurs proches et des responsables d’associations sportives, cet article analyse les modes de socialisation, les perceptions du corps et la construction des dispositions « masculines » dans deux quartiers populaires défavorisés dans la périphérie de Rabat. Dans ces quartiers, le football féminin est fréquemment considéré comme une pratique qui va à l’encontre des normes dominantes risquant de modifier l’hexis corporelle des filles. En parallèle, l’apparence masculine de certaines footballeuses est interprétée parfois comme une « perte de féminité » et interroge la binarité du genre tant dans les quartiers étudiés qu’au sein de la société. Par conséquent, l’engagement sportif de ces jeunes footballeuses se négocie en marge des conventions dominantes de genre.
Retrospective study of BRAFV600E mutation and CT features of papillary thyroid carcinoma
Authors: Hong Xiaoquan , Li Juxiang , Duan Shaoyin , You Youkuang 
Published: January 2024

Objective
This study aimed to examine the correlation between BRAFV600E status and computed tomography (CT) imaging characteristics in papillary thyroid carcinoma (PTC) and determine if suspicious CT imaging features could predict BRAFV600E status.

Methods
This retrospective study included patients with pathologically confirmed PTC at the Department of Thyroid Surgery of Zhongshan Hospital, Xiamen University, between July 2020 and June 2022. We compared the clinicopathologic factors and CT findings of nodules with and without the mutation, and the multiple logistical regression test was used to determine independent parameters of the BRAFV600E mutation.

Results
This study included 381 patients with PTC, among them, BRAFV600E mutation was detected in 314 patients (82.4%). Multivariate logistic regression analysis showed that gender (OR = 0.542, 95% CI [0.296–0.993], P = 0.047) and shape (OR = 0.510, 95% CI [0.275–0.944], P = 0.032) were associated with BRAFV600E mutation.

Conclusions
Compared to BRAFV600E mutation-negative, BRAFV600E-positive PTC lesions were more likely to be found in female patients and were characterized by irregular shape. However, the CT imaging finding is not enough to predict BRAFV600E status, but an indication.
Effect of Herbal Additives Amla (Emblica officinalis) and Giloy (Tinospora cordifolia) on Carcass Traits of Magra Lambs in the Semi Intensive Management System under the Arid Zone of Western Rajasthan
Authors: Joshi Abhishek , Saini Nirmala , Udawat Rajpal Singh , Saini Himanshu , Sharma Krishan Kumar , Goswami S. C. 
Published: January 2024

Aim: It was the objective of this study to determine whether the highly nutritious herbal feed additives Amla (Emblica officinalis) and Giloy (Tinospora cordifolia) impacted carcass traits of Magra lambs in the semi intensive system of management.
Study and Design: The experiment involved 28 lean lambs between the ages of three and four months under a semi intensive system, distributed at random into four experimental groups of seven lambs each, according to the randomized block design.
Place and Duration of Study: The campus is located at 236 meters above mean sea level in the heart of the Thar Desert at 28° 18' 0" N (28.3° N) latitude, 73° 30' 0" E (73.5° E) longitude and 28° 18' 0" N (28.3° N) latitude. The duration of experimental study was thirteen weeks.
Methodology: In a semi-intensive management system, groups T1 and T2 received an oral/feed supplement consisting of 1.5g/kg body weight of Amla (Emblica officinalis) fruit powder with seed and Giloy (Tinospora cordifolia) stem powder, respectively, along with concentrate, excluding the control group and T3. Group T3 group received an oral/feed supplement comprising a combination of Amla (Emblica officinalis) fruit powder and Giloy (Tinospora cordifolia) stem powder at a dosage of 0.75g/kg body weight, along with concentrate.
Results: At the end of experiment, no significant changes were found in carcass traits except hot and cold carcass weight though; they were within normal range.
Conclusion: At the end of experiment it appears that incorporation of 1.5g/kg body weight Giloy stem powder can be used as a part of the strategy as it is effective to alleviate stress in lambs in the semi-intensive system of arid zone of Rajasthan.
Multiple extranodal sites at presentation in non‐Hodgkin's lymphoma
Authors: Singh Devinder , Sharma Atul , Mohanti B.K. , Thulkar Sanjay , Bahadur Sudhir , Sharma S.C. , Gupta S. Dutta 
Published: August 2003

AbstractAbout one‐third of NHL patients present lymphomas at extranodal sites. Involvement of multiple noncontiguous extranodal sites at presentation without lymph node involvement is unknown. Herein we present two such cases. The first patient had sinonasal tract and urinary bladder NHL at presentation, while the other patient presented with bilateral adrenal involvement in addition to sinonasal tract NHL. Clinical presentation and pathophysiology are discussed, and a brief review of literature is included. Am. J. Hematol. 74:75–77, 2003. © 2003 Wiley‐Liss, Inc.
Autoimmune cytopenia does not predict poor prognosis in chronic lymphocytic leukemia/small lymphocytic lymphoma†
Authors: Kyasa Mouhammed J. , Parrish Rudolph S. , Schichman Steven A. , Zent Clive S. 
Published: August 2003

AbstractChronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is characterized by an acquired immune defect that can cause autoimmune complications, including anemia and thrombocytopenia. We conducted an observational study of the epidemiology, clinical presentation and significance of autoimmune complications of CLL/SLL in 132 patients from a large population (>45,000 veterans), in which at least 90% of patients with CLL/SLL have been previously identified. Over a period of 12.5 years, 12 patients (9.1%) had autoimmune complications; of these, 6 (4.5%) had autoimmune hemolytic anemia (AIHA), 5 (3.8%) had immune thrombocytopenia (ITP), and 1 (0.8%) had pure red blood cell aplasia (PRBA). All 6 cases of AIHA had a positive direct immunoglobulin test for IgG and C3d. In 6 patients, CLL/SLL was an incidental finding at the time of presentation with autoimmune cytopenia. Nine out of 10 patients responded to immunosuppressive therapy, which was complicated by serious infection in 7 cases, one of which was fatal. The major cause of mortality in patients with autoimmune complications of CLL/SLL was secondary malignancy. Survival of patients with immune cytopenia was not significantly different from CLL/SLL patients without immune cytopenia. Among patients with anemia or thrombocytopenia, mortality was significantly higher in those with bone marrow failure compared to an autoimmune etiology. We show that in a non‐referred population with a high incidence of CLL/SLL, autoimmune cytopenia can occur early in the natural history of the disease. These data suggest that the Rai and Binet classifications for CLL need to be modified for patients with autoimmune cytopenia. Am. J. Hematol. 74:1–8, 2003. Published 2003 Wiley‐Liss, Inc.
Evidence for expression of early myeloid antigens in mature, non‐blast myeloid cells in myelodysplasia
Authors: Xu Dongsheng , Schultz Cynthia , Akker Yelena , Cannizzaro Linda , Ramesh K.H. , Du Juan , Ratech Howard 
Published: August 2003

AbstractMyelodysplastic syndromes (MDS) are clonal hematopoietic stem cell disorders with frequent cytogenetic abnormalities. They can arise de novo or be related to therapy. Although blasts in MDS have been studied extensively, there is little information available on the mature, non‐blast myeloid cells (NBMCs). We used a retrospective case‐control study design. NBMC populations in MDS (48 cases) and in tumor‐free control (12 cases) bone marrow samples were analyzed using multiparameter flow cytometry for mean side scatter (SSC) channel number and for expression of aberrant cell surface antigens. MDS cases were stratified on the basis of cytogenetic abnormalities. We report that NBMCs in MDS with normal karyotype expressed significantly higher HLA‐DR than controls (P = 0.034). NBMCs in MDS cases with cytogenetic abnormalities and with ≥5% marrow blasts, compared with controls, had significantly higher CD34 and higher HLA‐DR but lower CD10 and lower SSC mean channel number. CD34 expression in NBMCs was significantly greater in therapy‐related MDS compared with de novo MDS ( P = 0.01), although the presence of cytogenetic abnormalities was not different ( P > 0.05). These data suggest that bone marrow, mature, NBMCs have phenotypic changes in MDS that are not seen in normal controls. Am. J. Hematol. 74:9–16, 2003. © 2003 Wiley‐Liss, Inc.
Impact of character correlation and variable groupings on modern human population tree resolution
Authors: Athreya Sheela , Glantz Michelle M. 
Published: August 2003

AbstractRelationships among modern human populations are often explored through the use of linear measurements taken on the cranium and expressed in the form of dendrograms. However, craniometric variables are strongly correlated and thereby violate the assumption of independence that most statistical analyses require. This study explores the relationship between differing methods of variable treatment and the statistical robustness of the outcomes they yield, as depicted in interpopulational trees of relatedness among modern humans. Three methods of grouping variables are examined. The first method leaves them ungrouped, the second groups variables on the basis of the developmental and/or functional complex of the cranium to which they are thought to belong, and the last method reduces variables by using principal components analysis. The strength of each of these methods is tested through the use of the Continuous Character Maximum Likelihood (CONTML) program in the PHYLIP phylogeny inference package. This program produces output in the form of trees, and the resolution of the branching topology is given as a log‐likelihood value, with statistical confidence intervals supporting each branch placement on the tree. The results indicate that leaving variables ungrouped provides misleadingly strong results by failing to account for character correlation. Of the alternative two grouping methods, the covarying components method yields the best‐resolved tree with stronger statistical support for its topology than the approach of grouping variables on the basis of their location on the cranium. Finally, the implications for interpreting population histories based on such methods are discussed. Am J Phys Anthropol 121:000–000, 2003. © 2003 Wiley‐Liss, Inc.
Brief communication: Sex determination accuracy of the minimum supero‐inferior femoral neck diameter in a contemporary rural Guatemalan population
Authors: Frutos Luis Ríos 
Published: August 2003

AbstractOne hundred and fourteen femora (75 male and 39 female) derived from a contemporary rural Guatemalan population were studied to test the ability of the minimum supero‐inferior femoral neck diameter as a sex indicator. With the discriminant functions previously developed from North American modern populations, a maximum of only 36% correctly sexed femora was obtained, with correct percentages as low as 4%. A new discriminant function for the Guatemalan rural population is presented, with a total of 89.5% correctly classified individuals. It is suggested that poor physical growth of the rural Guatemalan population, due to a stressful environment, can explain part of the metric differences observed between the North American and rural Guatemalan populations. Am J Phys Anthropol 121:000–000, 2003. © 2003 Wiley‐Liss, Inc.
Functional capabilities of modern and fossil hominid hands: Three‐dimensional analysis of trapezia
Authors: Tocheri M.W. , Marzke M.W. , Liu D. , Bae M. , Jones G.P. , Williams R.C. , Razdan A. 
Published: August 2003

AbstractThree‐dimensional (3D) trapezium models from Homo sapiens, Gorilla gorilla, Pan troglodytes, Australopithecus afarensis (A.L.333‐80), and Homo habilis (O.H.7‐NNQ) were acquired through laser digitizing. Least‐square planes were generated for each articular surface, and the angles between the planes were compared. Each extant species displays an overall pattern that distinguishes it from the others. The observed angles in G. gorilla and P. troglodytes are more similar to one other than either is to H. sapiens. Our results, obtained from using new 3D modeling and analytical tools, raise interesting questions about the functional capabilities of the fossil trapezia. Multivariate statistical analyses indicate that A.L.333‐80 is morphologically more similar to that of modern humans, whereas the O.H.7 trapezium is more similar to that of the gorilla. Significant differences between A.L.333‐80 and the extant species occur, but some similarities to humans suggest the ability to form the distinctively human forceful pad‐to‐side and three‐jaw chuck grips. Some key morphological differences from humans highlighted and quantified by our research suggest limitations in the functional capabilities of the O.H.7 trapezium, particularly in those that facilitate pronation at the base of the second metacarpal. If the O.H.7 trapezium represents part of the hand responsible for manufacturing and using the stone tools found at Olduvai, our results suggest that the hand manipulated the stones in a way for which we have no modern analog. Alternative considerations are that the O.H.7 trapezium is not representative of other trapezia from its species (i.e., N = 1), or that it represents another primate or hominid species. Am J Phys Anthropol, 2003. © 2003 Wiley‐Liss, Inc.
Hematological differences during growth among Tibetans and Han Chinese born and raised at high altitude in Qinghai, China
Authors: Garruto Ralph M. , Chin Chen‐Ting , Weitz Charles A. , Liu Ji‐Chuan , Liu Rui‐Ling , He Xing 
Published: August 2003

AbstractThis study describes the hemoglobin concentration ([Hb]) and hematocrit (HCT) of over 1,000 Tibetan and Han children, adolescents, and young adults who were born and raised at 3,200 m, 3,800 m, or 4,300 m in Qinghai Province, western China. At 3,200 m, no altitude effect is evident in the hematological characteristics of either group. At 3,800 m and 4,300 m, both groups show [Hb] and HCT values that are above low‐altitude norms. At both altitudes, Tibetan and Han children show no differences in the pattern of hematological response up to age 13. Among adolescents and young adults, however, the [Hb] and HCT of Han males and females are elevated compared to Tibetans. This indicates that the adolescent period may involve a divergence in the responses to hypoxia made by some individuals in these two groups. Also, many other adolescents and young adults in both groups show similar hematological characteristics, indicating that many Tibetans and Han share similar hematological responses to hypoxia. Am J Phys Anthropol, 2003. © 2003 Wiley‐Liss, Inc.
Growth and nutritional status of Khasi boys in Northeast India relating to exogamous marriages and socioeconomic classes
Authors: Khongsdier R. , Mukherjee Nandita 
Published: August 2003

AbstractThe Khasis are one of the matrilineal tribes of Meghalaya in Northeast India. They belong to the Indo‐Mongoloid racial stock, and speak the Monkhmer language of the Austro‐Asiatic group. They have their own traditional religion (Niam Khasi), but about 65% of them have converted to Christianity. A few Khasi members have also embraced Islam through matrimonial relationship with immigrant Muslim males. The present study was based on a cross‐sectional sample of 1,351 urban Khasi boys aged 3–18 years belonging to these three religious groups, with a view to understanding the effects of socioeconomic factors on growth and nutritional status, using anthropometric variables such as weight and height. The findings showed that about 60%, 29%, and 6% of these boys were below −2 Z‐scores of the US National Center for Health Statistics (NCHS) references in respect of weight for age, height for age, and body mass index for age, respectively. The logistic regression coefficient (β ± standard error) indicated that the prevalence of low weight for age (below −2 Z‐scores of the NCHS references) was positively associated with age (0.088 ± 0.014, P < 0.0001), while it was inversely associated with household income (−1.216 ± 0.030, P < 0.0001). Likewise, low height for age Z‐score was negatively associated with household income (−1.056 ± 0.130, P < 0.0001), although such a relationship was not significant in the case of low body mass index for age (−0.169 ± 0.229, P > 0.05). There were also significant differences between religious groups in respect of anthropometric variables. Allowing for household income, the ANCOVA test indicated that Muslim Khasi boys, who were the offspring of intermarriages between Khasi females and immigrant Muslim males, were significantly heavier and taller than Christian and Niam Khasi boys almost across ages. From about 3–10 years of age, Muslim Khasi boys were, on average, comparable to the 5th and 25th percentiles of the NCHS references of height and weight, respectively. Although it looks as though genetic mechanisms like heterosis and/or gene flow might also be associated with the larger body size in Muslim boys, such a conjecture could only be substantiated or refuted by further studies concerning genetic and more socioeconomic data on both immigrant and nonimmigrant populations. Am J Phys Anthropol, 2003. © 2003 Wiley‐Liss, Inc.
Ecology, habitat and bird community structure at Oussudu lake: towards a strategy for conservation and management
Authors: Chari K.B. , Abbasi S.A. , Ganapathy S. 
Published: August 2003

Abstract
Oussudu lake is a large, shallow wetland situated close to the city of Pondicherry, India. The lake harbours rich flora and fauna, and has been recognized as one of the important wetlands of Asia by the International Union for Conservation of Nature and Natural Resources (IUCN).
This paper summarizes the results of a 5‐year study on the annual composition, richness, diversity and population density of the bird community at Oussudu. A GIS database was developed on the basis of field surveys and allied studies.
The study reveals a declining trend in the number and diversity of the birds found at Oussudu with the exception of herons, egrets, plovers and lapwings. A relationship appears to exist between this decline in bird diversity and an increase in illegal fishing, cattle grazing, encroachments and pollution. These factors may have contributed to the decline of food and shelter for the birds.
A strategy has been developed for the conservation and management of the Oussudu catchment which would help in reversing undesirable trends.
Copyright © 2003 John Wiley & Sons, Ltd.