bluuebunny/crossref_metadata_2025_split huggingface dataset:
Repair of a Fistula between the Aorta and Right Ventricular Outflow Tract Secondary to Infective Endocarditis of a Unicuspid Aortic Valve and Previously Repaired Ventricular Septal Defect
Authors: Karsan Rickesh B. , O’Sullivan Katie E. , Lockhart Christopher J. , Austin Christopher 
Published: December 2023

Abstract
Background: Infective endocarditis of the aortic valve can result in a wide range of destructive pathology beyond the valve leaflets and annulus which require careful surgical planning to provide appropriate debridement and reconstruction. Failure to do so can result in a failure of surgical treatment, recurrent infection and cardiac failure with concomitant high morbidity and mortality.
Case report: We describe the case of a 45-year-old male with previous patch repair of a ventricular septal defect, who was diagnosed with sub-acute bacterial endocarditis of the native aortic valve and found to have a new fistula from the aorta to the right ventricular outflow tract managed surgically.
Conclusion: This unique case highlights another spectrum of infective endocarditis with a unique approach to repair and management.
Students and Instructors Reflections on the Impact of COVID-19 on Computer Science Education after One Year of Remote Teaching
Authors: Toti Giulia , Si Lei , Daniels David , Amoozadeh Matin , Alipour Mohammad Amin , Chen Guoning 
Published: December 2023

Abstract
In May 2020, 2 months after the COVID-19 pandemic caused institutions across the world to move all their courses online, we conducted a survey to evaluate the impact of this transition on a group of computer science students. That first survey highlighted mostly negative effects, with students struggling to perform many class-related activities. About a year later, after a full year of remote teaching, we wanted to see if and how the students' sentiment had changed.
To assess students' perceptions of remote teaching, we conducted a new survey composed of 41 between multiple choice, Likert scale and open ended questions. Additionally, we have also interviewed instructors of computer science courses, to learn about their experience and how they adapted to the new teaching modality.
137 students and 10 instructors have shared their feedback regarding their positive and negative experiences in the new learning format. Our results show that the students' experience has improved significantly, to the point that many of them expressed interest in continuing learning online, at least partially. Conversely, the instructors have concerns that this may not produce the best learning outcomes for the students. Our study also shows that some populations may still be at a disadvantage in this learning format.
The results and considerations included in this report may benefit the conversation on how to conduct computer science higher education in a post-pandemic world.
Knowledge, Attitude, Practice and Associated Factors toward Neonatal resuscitation among graduating health science students in Hadiya Zone Southern Ethiopia
Authors: Oshine Woldetsadik , Keto Terefe , Mohammed Ezedin , Hassen Mehuba , Bokona Getachew , Abemie Worku , Abebe Fikrtemariam , Murugan Rajalakshmi 
Published: December 2023

Abstract

Background
Neonatal resuscitation is a set of actions taken at the time of birth to help in the reestablishment of breathing and circulation. In the first four weeks of life, more than 2.4 million newborn babies die globally, its main cause was newborn asphyxia. Poor knowledge and skill of neonatal resuscitation by practitioners has a visible negative effect on neonates.
Aim
To assess knowledge, attitude, practice and associated factors toward neonatal resuscitation among graduating students of health science college in Hadiya Zone, Southern Ethiopia.
Methods
Institution-based cross-sectional study design was employed with 213 graduating students from February 27- March 27, 2023, with systematic random sampling method by using structured interviewer administered questionnaire for data collection to select 213 graduating students in Hadiya zone health science colleges. The data were entered into Epi-data version 4.6 and exported to SPSS version 27 for further analysis. Logistic regression model (AOR, 95% CI and p value < 0.05) was fitted to identify the factors affecting knowledge, attitude and practice of neonatal resuscitation.
Result
The graduating students had 58.2% of good knowledge on neonatal resuscitation, their attitude and practice were 53.1% and 55.9% respectively. Simulation based demonstration teaching was a single factor which has significant effect on the good knowledge and practice of the students in common with [AOR: 0.377, 95%CI: (0.19–0.73)] and [AOR: 0.28, 95%CI: (0.145–0.53)], respectively and educational level on knowledge [AOR: 3.49, 95%CI: (1.24–9.7)] and on the attitude of students towards neonatal resuscitation.
Conclusion and Recommendation:
The knowledge, attitude and practice of graduating health science students toward neonatal resuscitation were poor, therefore practical demonstration room setup must be well-equipped, adequate simulation-based demonstration and return practice is important to improve the participant’s knowledge, attitude practice toward neonatal resuscitation.
Analysis of practical training needs in Primary Care for medical students: an approach based on the mentoring model
Authors: Zaldúa Yoseba Cánovas , Pérez Eduardo Hermosilla , Redon Ermengol Coma , Real Andrés Fernández , Vidal-Alaball Josep , Noguerola Sara Rodoreda 
Published: December 2023

Abstract
Background The aim of the mentoring model is to coordinate a learning model of Family and Community Medicine (FCM) through an individualised and continuous relationship between the student and the family physician assigned as the mentor. It is proposed to work in an environment in which observation, critical dialogue and a timely and continuous approach to clinical practice are emphasised. This study seeks to understand the perception that medical students have of primary care internships based on the mentoring model.
Methods. Cross-sectional descriptive study based on a survey of undergraduate medical students at the Universitat Autònoma de Barcelona in the year 2022-2023.
Results. A total of 337 responses were obtained from medical students out of a total of 1894 enrolled students (17.7%) with representation by course and teaching unit. In relation to the 6 questions of the survey, it is noteworthy that 79.8% of the students (95% CI: 75.1% - 84.0%) consider the implementation of the mentor figure in primary care internships to be suitable. Regarding the extension of internships, 57.9% (95% CI: 52.4% - 63.2%) ask to extend them in primary care and 70.3% (95% CI: 65.1% - 75.2%) in the hospital. Regarding the quality of the internships, 83.4% (95% CI: 79.0% - 87.2%) consider them to be of good quality. Regarding quantity and duration, 58.5% (95% CI: 53.0% - 63.8%) would like to do more and 59.9% (95% CI: 54.5% - 65.2%) would like it to last for 6 or more weeks.
Conclusions. The study shows that the majority of medical students favour the mentoring model in primary care internships. They also positively perceive the quality of the internships but express the need to extend them and to have longer rotations in the last year. These results suggest that mentoring could improve the educational experience of medical students in primary care.
Toward optimal fitting parameters for multi-exponential DWI image analysis of the human kidney: A simulation study comparing different fitting algorithms
Authors: Jasse Jonas , Wittsack H.-J. , Thiel T. A. , Zukovs R. , Valentin B. , Antoch G. , Ljimani A. 
Published: December 2023

Abstract
Purpose: In DWI, multi-exponential signal analysis can be used to determine signal underlying diffusion components. However, the approach is very complex due to the inherent low SNR, the limited number of signal decay data points and the absence of appropriate acquisition parameters and standardised analysis methods.
Methods: Within the scope of this work, different methods for multi-exponential analysis of the diffusion signal in the kidney were compared. To assess the impact of fitting parameters, a simulation was conducted comparing the free non-negative (NNLS) and rigid non-linear least square (NLLS) fitting methods.
Results: The simulation demonstrated improved accuracy for NNLS in combination with AUC estimation. Furthermore, the accuracy and stability of the results were further enhanced utilizing optimized parameters, namely 350 logarithmically spaced diffusion coefficients within [0.7, 300] x 10-3 mm²/s and a minimal SNR of 100.
Discussion: The NNLS approach shows an improvement over the rigid NLLS method. This becomes apparent not only in terms of accuracy and omitting prior knowledge, but also in better representation of renal tissue physiology.
Conclusion: By employing the determined fitting parameters, it is expected that more stable and reliable results for diffusion imaging in the kidney can be achieved. This might enable more accurate DWI results for clinical utilisation.
A new and reliable method to obtain micropore volume in nanoporous solids by gas adsorption based on Dubinin works and the thickness of the adsorbed layer
Authors: Villarroel-Rocha Jhonny , Arroyo-Gómez José J. , Barrera Deicy , Sapag Karim 
Published: December 2023

Abstract
It is known that the use of the Dubinin-Radushkevich method in micro-mesoporous samples does not give adequate values of micropore volumes, unlike when the samples contain only microporous. Based on that, in this work, we propose an easy method to calculate a reliable micropore volume (VμP) of micro-mesoporous (nanopores) samples, separating the microporous region from the experimental isotherm. For this, the original isotherm is modified, estimating the thickness of the adsorbed layer (t) as a function of relative pressure and changing the external surface area (Sext) to obtain a Type I adsorption isotherm in the microporous region; then, the DR method can be applied to the modified isotherm. This proposal, named the DR_t method, allows the calculation of a reliable VμP of any nanoporous material using different adsorbates. Using this method, we analyzed adsorbents of distinct nature (i.e., carbons and silicas) with different adsorbates as N2 and O2 at 77 K, Ar at 87 K, and CO2 at 273 K. We used this method to calculate VμP in different samples and compare them with those obtained with the traditional DR method, highlighting that unlike the latter the DR_t method showed similar and consistent results with the different adsorbates. Therefore, the values of micropore volume calculated using the DR_t method demonstrate consistency across various adsorbates, not only for N2 but especially for CO2, which is suggested to analyze narrow micropore volumes.
A Novel Logistic Model for Predicting Risk Factors and Contribution of Cerebral Small Vessel Disease
Authors: Liu Xuhui , Xu Kaiqiang , Liang Cheng , Li Min mi , Kong XiangfengKong , SaiLiKe HaLaMuJiang 
Published: December 2023

Abstract
Background: Cerebral small vessel disease (CSVD) results in pathological alterations in the small arteries or veins of the brain, thereby significantly impairing brain functionality. This study aimed to examine the causative factors of small vessel disease and ultimately determined the proportion of each risk factor for CSVD by constructing a multivariate model based on stepwise regression.
Methods: A total of 164 hospitalized patients were involved in this study. The study period was from January 2022 to March 2023.The patients were analyzed for the presence of CSVD by magnetic resonance imaging (MRI). The presence of CSVD in patients was determined by magnetic resonance imaging, and history, coagulation indices, renal function related to CSVD, and serum biochemistry and Hcy results were analyzed.
Results: 164 patients were included in the safety analysis set, 73 ( 44.5% ) cases with CSVD and 91 ( 55.5% ) cases with no. of patients, and the median age of the patients was 66 ( 49 - 86 ) years.. The results of multivariate logistic model showed that yes of hypertension ( OR = 10.94%, 95% CI: 3.80% ~ 35.57%, P ＜0.001 ), HbA1c ( OR = 3.05%, 95% CI: 1.54% ~ 7.51%, P = 0.005 ), HCY ( OR = 1.45%, 95% CI: 1.22% ~ 1.82%, P ＜ 0.001 ), CRP ( OR = 2.21%, 95% CI: 1.25% ~ 4.10%, P = 0.008 ), TG ( OR = 3.80%, 95% CI: 1.62% ~ 10.00%, P = 0.004 ), and TC ( OR = 1.90%, 95% CI: 1.17% ~ 3.25%, P = 0.013 ) were risk factors for CSVD morbidity. The marginal R-squared ( R 2 M ) was 0.467. Among all the determinants, the weight of HCY ( 60.60% ) was maximum, followed by HbA1c ( 27.84% ).The quasi-curves plotted by using bootstrap method (999 times) showed a good agreement between the predictive model and the actual observations.
Conclusion: Hypertension, HbA1c, HCY, CRP, TG and TC were risk factors for CSVD morbidity, and controlling the above indicators within a reasonable range will help to reduce the incidence of CSVD.
Single-port laparoscopy-assisted determining the location of the tunica vaginalis cavity for transcrotal orchidopexy for palpable undescended testis
Authors: Li Yueyan , Yu Xianxian , Liu Shengnan , Chen Qiaolin , Lin Houwei 
Published: December 2023

Abstract
Objective: We report the introduction of a novel Single-port laparoscopy-assisted determining the location of the tunica vaginalis cavity for transcrotal orchidopexy for palpable undescended testis. In this article, we describe the SLDLTO technique and the outcomes.
Methods: 28 male children with confirmed inguinal cryptorchidism who underwent surgical treatment from from December 2022 to October 2023 were selected for this study. All children underwent surgical treatment with SLDLTO, and the operative time, hospital stay, and postoperative results and complications were recorded.
Results: All 28 cases underwent LAT-HSL with minimal perioperative complications, and all children were successfully discharged from the hospital postoperatively. At the postoperative follow-up, there was no retraction or atrophy of the testes, no incisional infection, no inguinal hernia or tunica vaginalis effusion.
Conclusion: SLDLTO allows for rapid and accurate localization of the tunica vaginalis cavity. The method is safe, easy to perform, and adaptable. Additionally, the scar is hidden, and the operation time is short.
Minimally Invasive K-wire Osteotomy versus Open Chevron Osteotomy for Hallux Valgus Correction
Authors: Hu Yao , He Zhitao , Yang Hu , Zhong Qigang , Meng Congpeng , Ma Zhida , Zhan Junfeng , Jing Juehua 
Published: December 2023

Abstract
Background
The treatment of hallux valgus has become increasingly minimally invasive. Following the framework of three generations of minimally invasive hallux valgus techniques, we designed the minimally invasive K-wire osteotomy (MIK) technique. We aimed to compare the radiological outcomes and clinical efficacy of the MIK technique with those of open surgery and to evaluate its clinical value.
Methods
In this retrospective study, we analyzed the data of patients who underwent hallux valgus surgery from July 2018 to July 2021. Patients were divided into the MIK and open groups according to the surgical method. Perioperative data, radiographicmeasurements of the hallux valgus angle (HVA) and intermetatarsal angle (IMA), American Orthopaedic Foot and Ankle Society Hallux Metatarsophalangeal-Interphalangeal Scale (AOFAS) scores, and visual analog scale (VAS) scores to assess efficacy were recorded.
Results
Seventy patients (72 feet) with hallux valgus were enrolled in this study, including 36 patients (38 feet) in the MIK group and 34 patients (34 feet) in the open group. The operation time and hospital stay were shorter in the MIK group than in the open group (P﹤0.05). No significant differences were observed in the HVA and IMA between the two groups at 6 weeks post-surgery and at the last follow-up (P﹥0.05). Six weeks post-operatively, the AOFAS and VAS scores of the MIK group were better than those of the open group (P﹤0.05). At the last follow-up, no significant difference was observed in the AOFAS and VAS scores between the two groups (P﹥0.05). The internal fixation was removed in one case in the MIK group and in two cases in the open group due to screw protrusion and skin irritation. No cases of wound infection, deformity recurrence, hallux varus, or metastatic metatarsalgia were observed in the two groups.
Conclusion
The MIK technique demonstrates comparable radiographic results and clinical efficacy to open surgery. It saves operation time and results in less trauma, less pain, faster functional recovery, and improved aesthetics. This technique does not require specialized equipment, making it suitable for application in most hospitals.
Hoist the colours: silviculture impacts butterfly assemblage colours in the Atlantic Forest
Authors: Thomas André Nogueira , Richter Aline , Spaniol Ricardo Luís , Mendonça Milton de Souza , Iserhard Cristiano Agra 
Published: December 2023

Abstract
Organismal colours have long captivated and inspired naturalists and scientists. Since colours depend on species' life history, it is expected that they respond to environmental changes, especially in an increasingly anthropized world. Aiming to evaluate how this trait responds to different anthropogenic disturbances, we assess wing colour aspects of fruit-feeding butterflies sampled in Atlantic Forest remnants. These remnants, with well-defined understory and canopy, are crossed by roads and trails acting as artificial edges and besiege exotic pine silviculture areas of different ages, representing landscapes commonly found in the subtropical Atlantic Forest. Through standardised photographs, we obtained colour measurements of brightness, saturation, contrast, colour diversity and heterogeneity, plus the presence of eyespots and iridescence for dorsal and ventral wing surfaces of 47 butterfly species, and evaluated their distribution and abundance in the distinct environments. We hypothesise colour variables will differ in each environment due to their biotic and abiotic differences, being less diverse in anthropized ones due to the pressures generated by disturbances. As expected, different natural environments have diverse and unique colour traits that are not found in anthropized ones; however, artificial edges present brighter and even more diverse colours. Pine silviculture areas, despite differing succession stages, all have decreases in colour diversity. We demonstrate that different anthropogenic actions can lead the most colourful species to disappear. Therefore, we argue butterfly colouration can be seen as a bioindicator, representing a useful form of functional biodiversity, providing conservation status and facilitating communication with the general public.
Gas-induced modulation of the surface structure of a Ni/Al2O3-CeO2 catalyst in CO methanation
Authors: Han Yi-Fan , Li Xinli , Fan Zhihui , Zhang Xiaonan , Zhang Shaokang , Zhang Zhenzhou , Tu Weifeng 
Published: December 2023

Abstract
The gas-induced strong metal-support interaction (SMSI) effects have proved to optimize the electronic states of active sites in heterogenous catalysis. A novel approach to tune the surface structure of a 10Ni/7Al2O3-3CeO2 catalyst has been developed by modulating the composition of the reaction atmospheres in CO methanation. The reaction rate was enhanced nearly eight-folds by gas-induced treatment. Multi-Operando/in situ techniques, such as in situ X-ray photoelectron spectroscopy (near ambient pressure, NAP-XPS), in-situ diffraction reflection infrared fourier transform spectroscopy (DRIFTS), Operando Raman spectroscopy and H2 uptakes, reveal that the origin of active sites is due to the great exposure of Ni nanoparticles after gas-induction, while the CeOx overlayer was partially reconstrued to yield more oxygen vacancies, which could enhance tracking Ni nanoparticles. Undoubtedly, Gas-induced effects altered the strong SMSI between Ni nanoparticles and the CeO2 support. This easy-to-run gas-induction method may make it possible to retroactively modulate the SMSI state to improve the performance of heterogenous catalysis, especially applied for syngas conversion.
Identification of biomarkers of bronchopulmonary dysplasia by single cell transcriptome sequencing technology and WGCNA：Data from bioinformatics analysis
Authors: Li Rong , Huang Dong 
Published: December 2023

Abstract
Bronchopulmonary dysplasia (BPD) is a disease of chronic lung dysfunction. We combined Weighted Gene Co-expression(WGCNA) and single-cell RNA analysis (scRNA-seq) to identify the biomarkers linked to BPD. Two data were obtained by searching the Gene Expression Omnibus (GEO) database with corresponding keywords, GSE190934 and GSE188944, the former for scRNA-seq and the latter for WGCNA. In the GSE190934 data, 10,762 differential genes showed up, with S100a9, S100a8, and Lyz2 being expressed primarily in pericytes. We have found that S100a8 was found to be significantly higher in the hyperoxia model mice. While Ccl5 was mainly located in CD4+ T cells, Ccl4 was mainly expressed in myeloid cells. In addition, the data has revealed that Emp2 is regarded as a marker of type I alveolar cells in BPD. Among the enriched signaling pathways by the GSE188944, several signaling communications were found to exhibit high expression patterns in BPD. The bioinformatics analysis identified some key genes and cellular communication components of BPD. These findings provide insights into the cellular and molecular underpinning of BPD pathological mechanisms.
Evaluation of Antimicrobial Activity of Coleus forskohlii on Periodontal Pathogenic Bacteria, An experimental in-vitro study
Authors: Faragalla Amel Ibrahim , Bahamdan Ghada Khalid , Abdullah Aseelah , Almoadi Raida , Fadul Mohammed , Majrashi Tagreed , Algarni Hasinah 
Published: December 2023

Abstract
Background:
Coleus Forskohlii (C.F.) is a typical indigenous medicinal plant from the Lamiaceae family grown widely in India. Coleus gained importance after discovering its therapeutic properties (Bone, 2007) and was reported to have some antibacterial activity. The current study tested the antibacterial effect of (C F) on certain periodontal pathogens.
Methods
An experimental Invitro-study was conducted at King Khalid University, to test the antibacterial activity of Coleus Forskohlii. Thirty plaque samples were collected from gingivitis patients, kept, and transported using nutrient broth to the microbiology lab. The (CF) extract was prepared from the plant's leaves and five solutions were produced (water, methanol, ethyl acetate, chloroform, and hexane). Following the bacterial culturing, the extract solutions were applied and the minimal inhibitory concentration (MIC) and the minimal bactericidal concentration (MBC) were measured.
Results
Various activities were demonstrated, indicating the positive inhibitory reactions of ethanolic extracts against many bacteria grown directly from plaque samples. Twenty-five bacterial species have been inhibited at 1g / mL concentrations. Most organisms (82.9%) have been inhibited at 1g / mL, whereas 34.3% were inhibited at 0.25 g/ mL, and only 5.7% were inhabited at 0.15 g/ mL; the latter two concentrations represented the MIC for most of the strains.
Conclusion
The ethanolic extract of Coleus forskohlii demonstrated effective antimicrobial activity. The ethanolic extract and water extracts showed different activities against the selected bacteria, but the ethanolic extract was superior to the water extract.