bluuebunny/crossref_metadata_2025_split huggingface dataset:
Optimized thermoelectric performance driven by A‐site deficient in SrxLa0.1TiO3−δ/TiO2−y composites
Authors: Lou Zhihao , Zhang Ping , Chen Penghui , Wei Ziyao , Gou Jianjun , Xu Jie , Gong Chunlin , Gao Feng 
Published: January 2024

AbstractFor thermoelectric applications at high temperatures, perovskite SrTiO3 is a promising contender as an n‐type oxide thermoelectric (TE) material. In this work, SrxLa0.1TiO3−δ/TiO2−y composite ceramics were successfully synthesized by solid state reaction, using a combination of A‐site cation vacancy and composite fabrication. Through X‐ray diffractometer and scanning electron microscopy analysis, a complex microstructure composed of two kinds of titanium oxides was formed after reductive sintering and annealing. In addition, controlling the content of Sr vacancies in the SrxLa0.1TiO3−δ matrix increased the thermoelectric power factor (PF) by optimizing the weighted mobility in the composite, resulting in the highest PF of 425.8 μW m−1 K−2 and the maximum ZT of 0.16 for the Sr0.875La0.1TiO3−δ/TiO2−y composite through the synergistic optimization of electrical and thermal transport properties. The strategy proposed in this study of design A‐site‐deficient composites with nano‐sized metal paved a new way to fabricate high performance oxide thermoelectric materials.
A theoretical framework for Acute Care Nurse Stress Appraisal: Application of the transactional model of stress and coping
Authors: de Cordova Pamela B. , Reilly Laura L. , Pogorzelska‐Maziarz Monika , Gerolamo Angela Marie , Grafova Irina , Vasquez Abigail , Johansen Mary L. 
Published: January 2024

AbstractAimTo develop a framework for understanding the stress appraisal process among acute care nurses during the COVID‐19 pandemic.DesignA secondary analysis of open‐ended responses from a cross‐sectional survey of 3030 frontline, acute care nurses in New Jersey and the effect of burnout during the COVID‐19 pandemic.MethodsLazarus and Folkman's transactional model of stress and coping guided the study. Thematic analysis was used to analyse 1607 open‐ended responses.ResultsNine themes emerged during the secondary appraisal of stress. Five themes contributed to distress and burnout including (1) high patient acuity with scarce resources, (2) constantly changing policies with inconsistent messaging, (3) insufficient PPE, (4) unprepared pandemic planning and (5) feeling undervalued. Four themes led to eustress and contributed to post‐traumatic growth including (1) team nursing to ensure sufficient resource allocation, (2) open channels of communication, (3) sense‐ of‐duty and (4) personal strength from new possibilities.ConclusionThe COVID‐19 pandemic was a traumatic event for patients and the nursing workforce. Internal and external demands placed on acute care nurses increased burnout, however, a subset of nurses with adequate support experienced personal growth.Implications for the Profession and/or Patient CareBeyond mental health interventions for acute care nurses, organizational interventions such as reevaluation of emergency action plans to optimize resource allocation, and work environment strategies such as improved communication and decision‐making transparency are necessary.ImpactTo better understand how frontline acute care nurses experienced stress during COVID‐19, a data‐informed framework was developed that included a primary and secondary appraisal of stress. Themes contributing to distress and burnout were identified, and themes leading to eustress and post‐traumatic growth were also identified. These findings can assist nurse leaders in optimizing strategies to reduce burnout and promote post‐traumatic growth in the post‐COVID years.Reporting MethodNo patient or public contribution.
COVID‐19 and collective trauma: Implementing a trauma‐informed model of care for post‐COVID patients
Authors: Barton Carly , Troy Lauren , Teoh Alan , Spencer Lissa , Reeves Jack , Cram Vincent , Wai Michael , Jones Lynette 
Published: January 2024

AbstractAimTo describe the implementation of a trauma‐informed model of care in the Post COVID Respiratory Clinic of a large tertiary referral centre in NSW.DesignDiscussion paper.Data SourcesEvidence gathered from a literature search (2008–2022) was used to develop a framework for management of patients presenting to this Post COVID Respiratory Clinic. This paper outlines the personal reflections of the clinic staff as they developed and implemented this framework. Ethical approval was obtained to report the data collected from patient reviews.DiscussionThe literature highlights the high prevalence of trauma in patients following COVID‐19 infection, as well as the larger population both during and after the pandemic. This experience of trauma was observed in patients seen within the clinic, indicating a need for specialized care. In response, a trauma‐informed model of care was implemented.ConclusionReconceptualizing COVID‐19 as a ‘collective trauma’ can help healthcare workers understand the needs of post‐COVID patients and enable them to respond empathetically. A trauma‐informed model is complementary to this cohort as it specifically addresses vulnerable populations, many of whom have been further marginalized by the pandemic.Implications for Nursing and Patient CareFrontline healthcare workers, particularly nurses, are well positioned to implement trauma‐informed care due to their high‐level of patient contact. Adequate allocation of resources and investment in staff is essential to ensure such care can be provided.Impact

The COVID‐19 pandemic has led to adverse physical and mental health outcomes for many.

Trauma‐informed care is a way to promote reengagement with the healthcare system in this group.

Post COVID patients globally may benefit from this approach, as it aims to build trust and independence.

Patient or Public ContributionFeedback was sought from a patient representative to ensure this paper adequately reflected the experience of the post‐COVID patient.
Research trends of game‐based language learning in K‐12 education: A systematic review of SSCI articles during 2009–2022
Authors: Yang Lu , Li Rui , Zhou Yu 
Published: January 2024

AbstractBackgroundWhile game‐based language learning (GBLL) in K‐12 education has received considerable attention, little is still known about its state‐of‐the‐art research trends over the last decade, necessitating a systematic review on its theoretical frameworks, instructional activities and research findings.ObjectivesTo fill the gap, drawing on the revised technology‐based learning model, this study aims to conduct a systematic review on the trends of GBLL for K‐12 education in terms of theoretical frameworks, participants, methodology, game genres, instructional activities and application effectiveness.MethodsBased on the proposed criteria, 83 Social Science Citation Index (SSCI) articles pertaining to GBLL in K‐12 education published during 2009–2022 were finalised for data analysis.Results and conclusionsThe results showed that (1) most GBLL studies adopted cognitive and social frameworks, including flow theory, situated learning and socio‐cultural theory; (2) the most common participants were primary school students, and the most common languages were English as a foreign language (EFL) learning; (3) quantitative methods were frequently adopted, with a particular eye on tests, questionnaires and experimental design; (4) the most common game genre was tutorial games; (5) pre‐game instructional activities, such as gameplay training and lecture, were mostly implemented in K‐12 contexts; (6) benefits such as enhancing four language skills and communicative competence and improving learners' attitudes were reported. However, according to the results, technical issues, unhelpful partners, difficult learning tasks and high cognitive load were the most frequently reported drawbacks.ImplicationsPedagogical implications for teachers, designers and researchers in GBLL were referred from the results of the study.
Bipolar catheter ablation with dedicated radiofrequency system for highly refractory ventricular arrhythmia—Does the rate of success depend on arrhythmia origin?
Authors: Gardziejczyk Piotr , Piotrowski Roman , Kryński Tomasz , Sikorska Agnieszka , Kułakowski Piotr , Baran Jakub 
Published: January 2024

AbstractIntroductionDespite rapid technological progress, some arrhythmias are still resistant to standard unipolar ablation. These include arrhythmias arising from the base of the heart, cardiac crux, or epicardium. Bipolar radiofrequency ablation (B‐RFA) may be useful in some cases, however, data on the efficacy of this approach in various arrhythmia localizations are scarce. The aim of this study was to assess the efficacy of B‐RFA in patients with ventricular arrhythmias originating from various locations, occurring refractory to standard unipolar ablation approaches.MethodsAn observational, single center study was conducted over a 30‐month period. B‐RFA were performed using dedicated radio frequency (RF) generator and electroanatomic mapping system.ResultsTwenty‐four procedures, in 23 patients with a median (range) of 1 (1–2) previously failed unipolar ablation procedures, were included in the final analysis. There were 12 ablations of ventricular arrhythmias originating from interventricular septum with an acute success rate of 75%, and 12 from left ventricular (LV) summit with an acute success rate of 58%. The midterm success rate (median interquartile range follow‐up of 205 days [188–338]) was 66% and 50%, respectively.ConclusionsB‐RFA is a promising method of catheter ablation for refractory cardiac arrhythmias. A higher success rate was observed in ablation for difficult ventricular arrhythmias originating from interventricular septal region than LV summit.
Investigation of extragonadal teratomas in two Poecilia wingei
Authors: Prazdnikov Denis V. , Kondakova Ekaterina A. 
Published: January 2024

AbstractTeratoma is a rare tumour in fish consisting of tissues from more than one germ layer, that may be located in either the gonads or extragonadal sites. Teratomas in many fish species remain poorly understood. In this work, we performed the first histological examinations of extragonadal teratomas in Poecilia wingei and also examined the influence of a large teratoma on male sexual activity. The studied teratomas shared general organizational features, but they also had variations in both external and internal features. In teratomas, the most common and highly differentiated tissues were striated muscle and nervous tissue. Despite the tumour, the male P. wingei exhibited normal mating behaviour and retained the ability for successful copulation. The structural features of extragonadal teratomas in guppy fish indicate a possible connection between these tumours and a failure of conserved processes operating in the embryonic germline.
Community social capital, managerial opportunistic behavior, and information uncertainty in IPO firms
Authors: Jin Shunyao , Lee Heiwai 
Published: January 2024

AbstractWe examine whether and how community social capital influences the information uncertainty of a private firm's going‐public process. We find that high social capital of the US counties in which IPO firms are headquartered significantly reduces underpricing and post‐IPO stock volatility. This relation is stronger under lessened disclosure requirements and less reputable underwriting. Further findings suggest that high social capital constrains IPO issuers from practicing opportunistic financial reporting. We document that high social capital is associated with a more readable prospectus, less financial misconduct, more readable annual reports, and better long‐run stock return performance in the years following the IPOs.
ChatGPT: The Sky is Not Falling
Authors: Blanke Jordan M. 
Published: January 2024

AbstractGenerative artificial intelligence (generative AI) applications such as ChatGPT and its brethren erupted onto the scene last year and have been quite a disruptor throughout higher education. Like much new technology, generative AI brings with it benefits and challenges. This note focuses on early experiences with ChatGPT, attempts to learn how to use it, and possible changes needed for our assessment methodologies. I provide some suggested modifications to traditional assignments to adapt to generative AI's ubiquity.
The effect of short‐term rentals on local consumption amenities: Evidence from Madrid
Authors: Hidalgo Alberto , Riccaboni Massimo , Velázquez Francisco J. 
Published: January 2024

AbstractThis paper examines the impact of the arrival of Airbnb on local consumption amenities in Madrid. We exploit the exogenous variation created by the timing and uneven distribution of Airbnb listings in the city to determine the impact on food and beverage establishments. Using an instrumental variable strategy, we find positive local effects on both the number of restaurants and their employees: an increase of 14 Airbnb rooms in a given census tract leads to almost one more restaurant, and the same increase in a given neighborhood generates 11 new tourist‐related employees. The results are robust to the specification and sample composition. This paper contributes to the literature on the economic impact of the platform economy on urban areas by providing evidence of market expansion externalities from short‐term rentals.
Greater sensitivity of the circadian system of women to bright light, but not dim‐to‐moderate light
Authors: Vidafar Parisa , McGlashan Elise M. , Burns Angus C. , Anderson Clare , Shechter Ari , Lockley Steven W. , Phillips Andrew J. K. , Cain Sean W. 
Published: January 2024

AbstractWomen typically sleep and wake earlier than men and have been shown to have earlier circadian timing relative to the light/dark cycle that synchronizes the clock. A potential mechanism for earlier timing in women is an altered response of the circadian system to evening light. We characterized individual‐level dose–response curves for light‐induced melatonin suppression using a within‐subjects protocol. Fifty‐six participants (29 women, 27 men; aged 18–30 years) were exposed to a range of light illuminances (10, 30, 50, 100, 200, 400, and 2000 lux) using melatonin suppression relative to a dim control (<1 lux) as a marker of light sensitivity. Women were free from hormonal contraception. To examine the potential influence of sex hormones, estradiol and progesterone was examined in women and testosterone was examined in a subset of men. Menstrual phase was monitored using self‐reports and estradiol and progesterone levels. Women exhibited significantly greater melatonin suppression than men under the 400‐lux and 2000‐lux conditions, but not under lower light conditions (10–200 lux). Light sensitivity did not differ by menstrual phase, nor was it associated with levels of estradiol, progesterone, or testosterone, suggesting the sex differences in light sensitivity were not acutely driven by circulating levels of sex hormones. These results suggest that sex differences in circadian timing are not due to differences in the response to dim/moderate light exposures typically experienced in the evening. The finding of increased bright light sensitivity in women suggests that sex differences in circadian timing could plausibly instead be driven by a greater sensitivity to phase‐advancing effects of bright morning light.
Efficacy and safety of DAA in children and adolescents with chronic HCV infection: A systematic review and meta‐analysis
Authors: Indolfi Giuseppe , Easterbrook Philippa , Giometto Sabrina , Malik Farihah , Chou Roger , Lucenteforte Ersilia 
Published: January 2024

AbstractBackground and AimsWe evaluated the effectiveness and safety of pan‐genotypic regimens, glecaprevir/pibrentasvir (GLE/PIB), sofosbuvir/velpatasvir (SOF/VEL), and sofosbuvir/daclatasvir (SOF/DCV) and other direct‐acting antivirals (DAA) regimens for the treatment of hepatitis C virus (HCV)‐infected adolescents (12–18 years), older children (6–11 years), and young children (3–5 years). The purpose of this systematic review and meta‐analysis was to inform the World Health Organization (WHO) guidelines.MethodsWe included clinical trials and observational studies published up to August 11, 2021, that evaluated DAA regimens in HCV‐infected adolescents, older children, and young children. We searched MEDLINE, EMBASE, and CENTRAL databases and key conference abstracts. Sustained virological response 12 weeks after the end of treatment (SVR12), adverse events (AEs), and treatment discontinuation were the outcomes evaluated. Risk of bias was assessed using a modified version of the ROBINS‐I tool. Data were pooled using random‐effects models, and certainty of the evidence was assessed using the GRADE approach.ResultsA total of 49 studies including 1882 adolescents, 436 older children, and 166 young children were considered. The SVR12 was 100% (95% Confidence Interval: 96–100), 96% (90–100), and 96% (83–100) for GLE/PIB in adolescents, older, and young children, respectively; 95% (90–99), 93% (86–98), and 83% (70–93), for SOF/VEL, respectively; and 100% (97–100) and 100% (94–100) for SOF/DCV in adolescent and older children, respectively. There was a clear trend towards a higher rate of any reported AE from adolescents (50%), older children (53%), to young children (72%). Serious AEs and treatment discontinuations were uncommon in adolescents and older children (<1%) but slightly higher in young children (3%).ConclusionsAll three pan‐genotypic DAA regimens were highly effective and well‐tolerated and are now recommended by the WHO for use in adults, adolescents, and children down to 3 years, which will simplify procurement and supply chain management. The evidence was based largely on single‐arm non‐randomized controlled studies. Moreover, there were also missing data regarding key variables such as route of HCV acquisition, presence or absence of cirrhosis, or HIV co‐infection that precluded evaluation of the impact of these factors on outcomes.PROSPERO RecordCRD42020146752.
An Inquiry‐based Approach to Understanding Well‐being and Smartphone Usage: Constructing Research with Adolescent Students
Authors: Cockerham Deborah , Tyler‐Wood Tandra , Lin Lin 
Published: January 2024

AbstractInquiry can be an effective educational strategy for building critical thinking and student agency, but it is also a catalyst for scientific research. This study built upon a foundation of inquiry as 25 adolescents participated in a nine‐week guided inquiry curriculum focused on smartphones and digital responsibility. As participants developed personally meaningful inquiries and designed investigations into smartphone usage, they became co‐researchers who conducted their own research studies at a large museum. The study examines to what extent participants show changes in their (1) sense of well‐being; (2) awareness of personal smartphone usage. Pre‐ and post‐intervention data compared participants' personal awareness of smartphone usage and investigated participants' well‐being. Results showed significant increases in positive affect and smartphone awareness, with significant decreases in negative affect. This study provides important insights for teachers and researchers by highlighting the positive educational impacts of two‐way dialogue between research and education.
Microglia: Activity‐dependent regulators of neural circuits
Authors: Durán Laforet Violeta , Schafer Dorothy P. 
Published: January 2024

AbstractIt has been more than a century since Pío del Río‐Hortega first characterized microglia in histological stains of brain tissue. Since then, significant advances have been made in understanding the role of these resident central nervous system (CNS) macrophages. In particular, it is now known that microglia can sense neural activity and modulate neuronal circuits accordingly. We review the mechanisms by which microglia detect changes in neural activity to then modulate synapse numbers in the developing and mature CNS. This includes responses to both spontaneous and experience‐driven neural activity. We further discuss activity‐dependent mechanisms by which microglia regulate synaptic function and neural circuit excitability. Together, our discussion provides a comprehensive review of the activity‐dependent functions of microglia within neural circuits in the healthy CNS, and highlights exciting new open questions related to understanding more fully microglia as key components and regulators of neural circuits.
Multiple strategies, including 6mA methylation, affecting plant alternative splicing in allopolyploid peanut
Authors: Wang Lihui , Chen Hua , Zhuang Yuhui , Chen Kun , Zhang Chong , Cai Tiecheng , Yang Qiang , Fu Huiwen , Chen Xiangyu , Chitkineni Annapurna , Wang Xiyin , Varshney Rajeev K. , Zhuang Weijian 
Published: January 2024

SummaryAlternative splicing (AS), an important post‐transcriptional regulation mechanism in eukaryotes, can significantly increase transcript diversity and contribute to gene expression regulation and many other complicated developmental processes. While plant gene AS events are well described, few studies have investigated the comprehensive regulation machinery of plant AS. Here, we use multi‐omics to analyse peanut AS events. Using long‐read isoform sequencing, 146 464 full‐length non‐chimeric transcripts were obtained, resulting in annotation corrections for 1782 genes and the identification of 4653 new loci. Using Iso‐Seq RNA sequences, 271 776 unique splice junctions were identified, 82.49% of which were supported by transcriptome data. We characterized 50 977 polyadenylation sites for 23 262 genes, 12 369 of which had alternative polyadenylation sites. AS allows differential regulation of the same gene by miRNAs at the isoform level coupled with polyadenylation. In addition, we identified many long non‐coding RNAs and fusion transcripts. There is a suppressed effect of 6mA on AS and gene expression. By analysis of chromatin structures, the genes located in the boundaries of topologically associated domains, proximal chromosomal telomere regions, inter‐ or intra‐chromosomal loops were found to have more unique splice isoforms, higher expression, lower 6mA and more transposable elements (TEs) in their gene bodies than the other genes, indicating that chromatin interaction, 6mA and TEs play important roles in AS and gene expression. These results greatly refine the peanut genome annotation and contribute to the study of gene expression and regulation in peanuts. This work also showed AS is associated with multiple strategies for gene regulation.
Unveiling the mechanism of broad‐spectrum blast resistance in rice: The collaborative role of transcription factor OsGRAS30 and histone deacetylase OsHDAC1
Authors: Hou Jiaqi , Xiao Huangzhuo , Yao Peng , Ma Xiaoci , Shi Qipeng , Yang Jin , Hou Haoli , Li Lijia 
Published: January 2024

SummaryRice blast, caused by Magnaporthe oryzae, significantly impacts grain yield, necessitating the identification of broad‐spectrum resistance genes and their functional mechanisms for disease‐resistant crop breeding. Here, we report that rice with knockdown OsHDAC1 gene expression displays enhanced broad‐spectrum blast resistance without effects on plant height and tiller numbers compared to wild‐type rice, while rice overexpressing OsHDAC1 is more susceptible to M. oryzae. We identify a novel blast resistance transcription factor, OsGRAS30, which genetically acts upstream of OsHDAC1 and interacts with OsHDAC1 to suppress its enzymatic activity. This inhibition increases the histone H3K27ac level, thereby boosting broad‐spectrum blast resistance. Integrating genome‐wide mapping of OsHDAC1 and H3K27ac targets with RNA sequencing analysis unveils how OsHDAC1 mediates the expression of OsSSI2, OsF3H, OsRLR1 and OsRGA5 to regulate blast resistance. Our findings reveal that the OsGRAS30–OsHDAC1 module is critical to rice blast control. Therefore, targeting either OsHDAC1 or OsGRAS30 offers a promising approach for enhancing crop blast resistance.