bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cultivation practices of leafy vegetable production during the wet season in Ambon, Indonesia
Authors: Hindersah Reginawanti , Kalay Agustinus Marthin , Salman Rion Suaib , Paays Wilhelmina , Banerjee Saon 
Published: January 2024

Green cabbage, water spinach, and spinach are important vegetables in the diet of the Ambonese communities, so the vegetables have economic value and contribute to the inflation of Ambon City. The main obstacle for optimizing leafy vegetables in urban farming of Ambon City in Ambon Bay neighborhood is excess water during the rainy season which possibly induces plant diseases and reduces the yield. The purpose of this study was to verify the 11-year weather of Ambon Bay; and the adaptation of vegetable farmers in Ambon City to the change of rainy season as well as precipitation in the study location The research was conducted using a qualitative descriptive method based on interviews with farmers supported by climate data for 11 years. This study explains that the rainfall was variable during 10 years; In 2010-2013 and 2017-2020, the annual rainfall was 3.950-5.264, while in 2014-2016 it ranged from 2.017-2.995 mm. Farmers adapt to high rainfall by installing plastic rain shelters, shortening the planting distance from 20 cm to 10 cm, and changing the planting calendar. However, in general growers install rain shelters during vegetable cultivation in the wet season resulting in high productivity of leafy vegetables.
Evaluating the role of credit facilities as drivers to small scale rice farmers’ productivity in Wukari local government area, Taraba state, Nigeria
Authors: Ukpe Udeme Henrietta , Saidu Duwangs Moses 
Published: January 2024

The role played by credit for sustainable agricultural activities cannot be overemphasized. The study evaluated the role of credit facilities as drivers to small scale rice farmers’ productivity in Wukari Local Government Area Taraba State, Nigeria. A multi stage sampling procedure was used to sample 250 respondents from the study area. The study found that seed (p = 0.03), fertilizer (p = 0.01), and farm size (p = 0.01) were the key determinants of productivity for the rice farmers who had access to credit facilities while labour (p = 0.056) and seed (p = 0.01) were the determinants of productivity for the non-access to credit facilities counterparts. The finding show that years in school, farm size and age are the factors that influenced access to credit facilities. Finally, interest rate (92.8%), lack of collateral security (89.6%), lending criteria (72%) and government regulations (70.8%) are the major problem associated with access to credit facilities. It was therefore recommended that Public and private partnerships should be encouraged to develop innovative financial products and services tailored farmer’s activities with a goal of offering competitive interest rates. Continuous review and policies adaptation related to interest rates in agricultural lending to ensure they remain effective and responsive to changing economic conditions and the needs of farmers.
Experiências para a desjudicialização da saúde no Brasil
Authors: Diniz Silva Ludmilla , Veloso Oliveira Figueiredo Iara , Bahia Felicíssimo Zocratto Keli , Debôrtoli de Miranda Wanessa 
Published: January 2024

Objetivos: Descrever a experiências para a desjudicialização da saúde no Brasil. Trata-se de uma revisão integrativa. Metodologia: Realizou-se uma Revisão Integrativa da literatura com buscas na Biblioteca Virtual em Saúde (BVS), Scientific Electronic Library Online (Scielo), Cadernos Ibero-Americanos de Direito Sanitário, Revista de Direito Sanitário da Universidade de São Paulo e Google acadêmico. Resultados e discussão: Os artigos analisados são unânimes em apresentar experiências exitosas que estabelecem arranjos institucionais dialógicos. Algumas experiências se destacam: Câmara Permanente Distrital de Mediação em Saúde (CAMEDIS) da Defensoria Pública do Distrito Federal; espaços de mediação e resolução de conflitos instituído pelo Ministério Público de Minas Gerais; Câmara de Resolução de Litígios em Saúde (CRLS), no Rio de Janeiro; e “SUS Mediado”, câmara de conciliação no estado do Rio Grande do Norte. Em contrapartida, a única experiência não exitosa identidicada, não contou com participação plural dos setores interessados na temática. Os achados apontam que a desjudicialização é um caminho promissor e viável. Conclusões: Há necessidade de consenso como estratégia pré-processual, destacando os canais de comunicação entre os profissionais de saúde, executivo e o judiciário, o estabelecimento de câmaras de mediação e conciliação que tem um baixo custo, são céleres e visam suprimir conflitos e reduzir as demandas judiciais desnecessárias dos litígios em saúde.
O efeito da pandemia de COVID-19 na coleta de material do colo do útero para exame citopatológico no Brasil
Authors: DIAS LACI MARCOS , Montagner Maria Inez 
Published: January 2024

Objetivo: verificar o efeito da pandemia de COVID-19 no procedimento de coleta de material de colo do útero para exame citopatológico. Metodologia: Tratou-se de uma pesquisa quantitativa, em que as informações foram obtidas no site oficial do Ministério da Saúde, DATASUS, com busca sobre a produção ambulatorial no Sistema Único de Saúde, por local de atendimento, com o levantamento de dados referente à quantidade aprovada, por ano de processamento, segundo a Região/Unidade da Federação, do procedimento 0201020033, coleta de material do colo do útero para exame citopatológico , do grupo 02 (dois), procedimentos com finalidade diagnóstica, sendo analisado o período compreendido entre janeiro de 2016 a dezembro de 2021.Resultados e Discussão. No período estudado foram realizados 51.472.809 procedimentos de coleta de material do colo do útero em todo o país. Sendo região sudeste a que mais realizou esse procedimento com 23.411.334 e a região Centro Oeste com apenas 2.935.699, a que menos fez a coleta de material uterino. Discutiu-se então, o impacto das notas técnicas emitidas pelo INCA, direcionando os profissionais a orientarem a população a não procurarem por esse tipo de procedimento durante a pandemia e como se dará a retomada das coletas de material pós pandemia. Conclusão. Observou-se, que houve uma redução dos procedimentos preventivos de coleta de material uterino, conforme os dados apurados em todo território nacional, devido a suspensão dos serviços, acarretando um grande volume de exames não realizados.
Penerapan Model Problem Based Learning (PBL) untuk Meningkatkan Kemampuan Berpikir Kritis dan Kreatif
Authors: Hastawan Innestasia , Suryandari Kartika Chrysti , Ngatman Ngatman 
Published: January 2024

Pendidikan pada abad 21 menekankan pada pembelajaran berbasis masalah, dengan empat keterampilan utama yang perlu dimiliki oleh siswa yaitu berpikir kritis, berpikir kreatif, komunikasi, dan kolaborasi. Penelitian ini bertujuan untuk meningkatkan kemampuan berpikir kritis dan kreatif siswa kelas V melalui penerapan model pembelajaran <em>Problem Based Learning</em> pada mata pelajaran IPA SDN 1 Gesikan Kebumen Tahun ajaran 2022/2023. Desain penelitian ini adalah penelitian tindakan kelas (PTK) yang dilaksanakan dalam 3 siklus. Hasil penelitian menunjukkan kemampuan berpikir kritis siswa yang diukur dari soal <em>HOTS</em> pada siklus I = 70,58%, siklus II = 82,35%, siklus III = 85,35%. Kemampuan berpikir kreatif siswa yang diukur melalui pembuatan peta konsep pada siklus I = 52,94%, siklus II = 76,47%, dan siklus III = 82,35%. Sehingga dapat disimpulkan bahwa model <em>PBL</em>dapat meningkatkan kemampuan berpikir kritis dan kreatif siswa.<p> </p><div id="pip-toast"> </div>
Penerapan Model Quantum Teaching dengan Multimedia untuk Meningkatkan Hasil Belajar pada Pembelajaran IPA Siswa Kelas V
Authors: Wulansari Elok , Wahyudi Wahyudi , Suryandari Kartika Chrysti 
Published: January 2024

<p>Penelitian ini merupakan penelitian tindakan kelas. Tujuan penelitian ini adalah mendeskripsikan langkah-langkah model Quantum Teaching dengan Multimedia, meningkatkan hasil belajar dan mendeskripsikan respon siswa terhadap multimedia. Subjek penelitian adalah guru dan siswa kelas V SDN 1 Kuwayuhan yang berjumlah 21 siswa dengan 8 siswa laki-laki dan 13 siswa perempuan. Data yang digunakan berupa data kualitatif dan kuantitatif. Teknik pengumpulan data menggunakan observasi, wawancara, dan tes. Validitas data menggunakan triangulasi teknik dan sumber data. Analisis data dilaksanakan melalui reduksi data, penyajian data, dan penarikan kesimpulan. Hasil penelitian menunjukkan peningkatan kemampuan berkomunikasi dan hasil belajar dengan menerapkan model Quantum Teaching dengan Multimedia. presentase hasil belajar siswa pada siklus I=88,09%, pada siklus II=88,09%, dan pada siklus III=95,23%. Kesimpulan penelitian ini adalah meningkatnya hasil belajar melalui penerapan model Quantum Teaching dengan Multimedia pada Pembelajaran IPA materi perubahan suhu dan wujud benda pada siswa kelas V SDN 1 Kuwayuhan tahun ajaran 2022/2023. </p><div id="pip-toast"> </div>
Plugging Mechanism of Rigid and Flexible Composite Plugging Materials for Millimeter-Scale Fractures
Authors: Bai Yingrui , Liu Yuan , Sun Jinsheng , Lv Kaihe 
Published: January 2024

Summary
Drilling-fluid loss caused by millimeter-scale fractures is a notoriously difficult problem in drilling engineering, and both rigid and flexible plugging materials are commonly used to address this issue. This investigation aims to comprehensively explore the plugging efficacy and underlying mechanisms of rigid, flexible, and fiber materials when used individually and in combination. The findings of our investigations into macroscopic high-temperature and high-pressure plugging experiments divulge a revelation: Under conditions of enhanced concentration, rigid particles evince the remarkable ability to engender a pressure-enduring plugging stratum; in contrast, independent attempts by flexible and fiber materials to yield a stable plugging layer are challenging. In this context, the optimal ratio of rigid, flexible, and fiber materials has been determined through composite plugging experiments. Calcite particles with a concentration of 5–8%, rubber particles with a concentration of 2–3%, and polypropylene fibers with a concentration of 1–2% were compounded for fracture plugging with widths of 1 mm, 3 mm, and 5 mm, respectively. The resulting plugging strengths were 10 MPa, 9 MPa, and 7 MPa. The microscopic visualized plugging experiments showed that the rigid particles form an I-shaped plugging layer with high strength but are difficult to transport to the deep part of the fracture. Flexible particles can be transported into the deep part of the fracture to form a plugging layer, but the “V”-shaped formation is unstable and has low strength. Based on the experimental results of “rigid-flexible synergistic” composite bridging-plugging formulations for different scales of fractured strata, the preferred template for bridging-plugging material formulations in the field is investigated to provide a reference for the bridging-plugging material formulations in the field.
Bee cups 2.0: P-Cups as single-use cages for honey bee experiments
Authors: Evans Jay D. , Chen Yanping , Lamas Zachary , Markowitz Lindsey , Palmer-Young Evan , Boncristiani Dawn 
Published: January 2024

Abstract
Honey bees and other pollinators face threats from pesticides, imperfect nutrition, and a diverse set of parasites and pathogens. Honey bees are also a research model for development, social behavior, microbiology, and aging. Tackling these questions requires a mix of in-hive and controlled laboratory experiments. We have perfected small-scale, inexpensive, disposable, rearing arenas for honey bees that have proved useful for hundreds of bioassays with thousands of bees. We describe those arenas here and provide links to videos demonstrating their many uses.
Microbiome changes in a stranding simulation of the holopelagic macroalgae Sargassum natans and Sargassum fluitans
Authors: Mendonça Inara R. W. , Theirlynck Tom , Zettler Erik R. , Amaral-Zettler Linda A. , Oliveira Mariana Cabral 
Published: January 2024

Abstract

Holopelagic Sargassum has been causing massive strandings on tropical Atlantic Ocean shorelines. After stranding, the algal biomass starts to decompose, releasing nutrients, toxic gases, and potentially introduces exogenous macro and microorganisms. Describing the microbiome associated with Sargassum, and how it changes after stranding is important in identifying potential microbial introductions to coastal environments, as well as sources of potential biotechnological resources. In this study, stranding simulation exploratory experiments were done for S. fluitans III and S. natans VIII on shipboard. Samples for microbiome identification were taken at 0 hr, just after removing healthy Sargassumfrom the seawater, and after 24 and 48 hrs of stranding simulation under environmental conditions. The bacterial community was identified through sequencing of 16S rRNA gene V3-V4 hypervariable regions, generating a total of 2,005 Amplicon Sequence Variants (ASVs). Of those, 628 were shared between Sargassum species. The stranding simulation changed the microbial community and only 30, out of 2,005 ASVs, persisted throughout the experiment. Phototrophs were in the main functional group at 0 hr, shifting to chemoheterotrophs within the first 24 hrs of exposure of Sargassum to air conditions. The most abundant orders Microtrichales and Rhodobacterales at 0 hr, were replaced after 24 hrs of exposure by Alteromonadales and Vibrionales, the latter representing up to 91% of the relative abundance in the bacterial community. Even though these are initial results they emphasize the need to better investigate the microbiome once its biomass could become a fertile ground for potentially pathogenic bacteria.
RAS-p110α signalling in macrophages is required for effective inflammatory response and resolution of inflammation
Authors: Castellano Esther , Rosell Alejandro , Krygowska Agata , Alcón Marta Alcón Pérez , Voisin Mathieu-Benoit , de Paz Juan , Sanz-Fraile Héctor , Rajeeve Vinothini , Berral-González Alberto , Cuesta Cristina , Swinyard Ottilie , Gabandé-Rodriguez Enrique , Downward Julian , Alcaraz Jordi , Rivas Javier De Las , Cutillas Pedro 
Published: January 2024

Abstract

Macrophages are crucial in the body's inflammatory response, with tightly regulated functions for optimal immune system performance. Our study reveals that the RAS-p110α signalling pathway, known for its involvement in various biological processes and tumorigenesis, regulates two vital aspects of the inflammatory response in macrophages: the initial monocyte movement and later-stage lysosomal function. Disrupting this pathway, either in a mouse model or through drug intervention, hampers the inflammatory response, leading to delayed resolution and the development of more severe acute inflammatory reactions in live models. This discovery uncovers a previously unknown role of the p110α isoform in immune regulation within macrophages, offering insight into the complex mechanisms governing their function during inflammation. With emerging potential to activate p110α using small molecules, targeting the RAS-p110α pathway could be a promising approach for treating chronic inflammation. This therapeutic prospect holds significant promise for easing inflammatory disorders and improving the quality of life for affected patients.
Navigating the Ethical Landscape of the Artificial Placenta: A Systematic Review
Authors: Cavolo Alice , Boer Angret , Proost Lien , Verweij E. J. , Gastmans Chris 
Published: January 2024

Abstract
Objective: To present the ethical debate on the artificial placenta (AP) by identifying, distinguishing, and organizing the different ethical arguments described in the existing literature.
Method: We conducted a systematic review of the AP ethical literature. Articles were selected based on predefined inclusion criteria: discussing ethical arguments, on AP, written in English. QUAGOL methodology was used for analysis.
Results: Forty-five articles were included. We identified three main themes. First, foundational-ethical issues. There is substantial disagreement on whether the AP subject should be considered an infant or a new moral entity. While physiologically it stays a fetus, it sits outside the womb. Second, reproductive ethics issues. Few authors believed that the AP would increase reproductive choices. However, the majority warned that the AP could limit reproductive choices by creating pressure to use it in healthy pregnancies or as an alternative to abortion. Third, research ethics issues. Publications mostly focused on selection of the in-human trial participants.
Conclusions: AP ethical literature focuses mostly on the potential use of AP as an alternative to
abortion or healthy pregnancies rather than on the intended use as treatment after extremely premature birth. Furthermore, all but one article originated from high-income western countries, and no article discuss the AP from a global health perspective. We conclude, therefore, that the current ethical literature on AP is imbalanced: it leans more towards science fiction than actual clinical and technological reality, and important perspectives like global health are currently missing from the existing body of literature.
Theoretical study on copper adsorption on ZnO surfaces for CO2 hydrogenation to methanol
Authors: Salmi Mustafa Al 
Published: January 2024

Abstract

The study of Cu on ZnO surfaces is a topic of ongoing research due to the importance of Cu as a promoter in the low-temperature synthesis of methanol, the water-gas shift process, and methanol steam reforming. The role of ZnO in supporting the stabilization of the Cu atoms and promoting the CO2 hydrogenation reaction is multifaceted and involves a range of physical and chemical factors. In this work, we used density functional theory (DFT) calculations to investigate the Cu adsorption on ZnO surfaces on different sites. Bader charge analysis, adsorption energy, and phonon inelastic neutron scattering (INS) associated with most stable systems were calculated and compared with previous theoretical and experimental results. We found that atomic Cu adsorption on hollow site of ZnO(111) is the most stable site and most favorable site for Cu adsorption comparing to other ZnO surfaces. This is due to the strong metal-oxygen interaction between Cu and the ZnO surface. The results suggest that the Cu/ZnO catalyst with Cu atoms at hollow site is most likely to be active for CO2 hydrogenation. We concluded that further studies are needed to investigate the catalytic activity of this catalyst under realistic reaction conditions with realistic models of Cu supported on ZnO.
The Effects of Reviewers Security and Privacy Perceptions on Fin Apps’ Performance: A Textual Analysis
Authors: Alnsour Yazan , Juma'h Ahmad H. 
Published: January 2024

Abstract
App providers find strategic value in the abundant reviews generated by online users. We explored how Fin app users express concerns about information security and privacy in their reviews and examined the impact of these concerns on the overall app rating. Utilizing online reviews from various Fin apps, we conducted textual analysis and employed a semi-supervised machine-learning model to understand user perceptions of security and privacy. The primary findings indicate that perceived concerns about security and privacy have a negative impact on app performance.
Decreased Neuronal Excitability in an ApoC2-Deficient Hamster Hypertriglyceridemia Model with Acute Seizure
Authors: Shen Qiuyue , Liu Nana , Wang Yuhui , Xian Xunde , Jiang Yuwu , Liu Lili , Hou Xinlin 
Published: January 2024

Abstract
The aim of this study is to use genetically modified hamsters with hypertriglyceridemia (HTG) to investigate the effects of high triglycerides on neuronal excitability and to characterize the mechanisms of these effects. Then, to identify novel therapeutic targets for the treatment of neonatal seizures. Acute seizure model was generated by intraperitoneal injection of pentylenetetrazol (PTZ) in homozygous ApoC2 knockout hamsters (ApoC2−/−). The number of tonic-clonic seizures was observed. Excitatory postsynaptic potentials (EPSPs) and action potentials (APs) of pyramidal neurons in the frontal cortex were recorded in wild-type and ApoC2−/− hamsters. HE staining and Nissl staining were performed to observe neuronal morphology of the frontal cortex. Fatty acid metabolomic analysis was applied to microdialysate from the frontal cortex after seizures, and mRNA changes were investigated as well. The frequency of grade IV/V seizures was higher in wild-type hamsters than in ApoC2−/− hamsters. Additionally, frequencies of EPSPs and APs were significantly lower in ApoC2−/− hamsters than in wild-type hamsters. Free palmitic acid in the frontal cortex dialysate showed a significant decrease in ApoC2−/− hamsters compared to wild-type hamsters after PTZ injection. Palmitoyl acyltransferase (PAT) ZDHHC14 expression in the frontal cortex was higher in ApoC2−/− hamsters than in wild-type hamsters. In ApoC2−/− model, the frequency of PTZ-induced seizures reduced, and the excitability of neurons decreased; we also found a significant decrease in free palmitic acid levels and observed an upregulation of ZDHHC14. Overall, our results demonstrated that the physiological environment of high triglycerides regulates neuronal excitability and palmitoylation modification may be involved in this mechanism.
Assessment of subclinical left ventricular systolic and diastolic dysfunction in patients with Type 2 diabetes mellitus on follow up at Tikur Anbessa Specialized Hospital: A Case - Control Study
Authors: Seleshi Tigist , Gebremariam Tewodros , Mekonnen Dufera , Tesfaye Demu , Markos Sura , Getachew Yitagesu , Taddese Konno , Guteta Senbeta 
Published: January 2024

Abstract
Background
People with diabetes are at increased risk of cardiovascular diseases. And cardiovascular diseases are the most common cause of morbidity and mortality in diabetic patients. A peculiar feature of cardiovascular diseases in diabetic patients is that they can have a significant level of heart disease while being asymptomatic. There is a paucity of data regarding the subclinical imaging features of diabetes in Africa, particularly in Ethiopia.
Objective
Our main objective was to compare the magnitude and spectrum of left ventricular systolic and diastolic dysfunction among asymptomatic Type 2 diabetic patients versus a normotensive, non-diabetic control group. We also assessed the determinants of left ventricular diastolic and systolic dysfunction in these patients.
Methods
This is a case-control study that was conducted at the Tikur Anbessa specialized hospital in Addis Ababa, Ethiopia. Standard transthoracic echocardiography was done for all selected patients with Type 2 diabetes mellitus on follow-up and for normotensive and non-diabetic controls that came to the hospital for other complaints. Ethical approval was obtained from the IRB of the department. Structured questionnaires were used to collect baseline characteristics, comorbidities, HgbA1c, LDL, triglyceride levels, and the duration and complications of diabetes. Statistical analysis was done using SPSS 25.0.
Results
The mean age of participants was 56 in both groups, with a similar proportion of male and female participants (56% and 44%, respectively). Left ventricular systolic and diastolic dysfunction were significantly more prevalent among diabetic patients than their sex and age matched controls. Within the diabetic participants aged > 60, dyslipidemia, metformin and glibenclamide use, a high serum triglyceride level, neuropathy, and statin use were found to be associated with the occurrence of left ventricular diastolic dysfunction. Chronic kidney disease and neuropathy were associated with left ventricular systolic dysfunction.
Conclusion
Left ventricular systolic and diastolic dysfunction were significantly more prevalent among diabetic patients than their sex and age matched controls.