bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Kinesio taping on posture, balance and gait in spastic cerebral palsy – A systematic review
Authors: Banerjee Srishti B. 
Published: December 2023

ABSTRACT

Background:
Cerebral palsy (CP) is a nonprogressive developmental disorder characterized by motor deficits, such as abnormal posture, balance, and gait impairments leading to deformities, affecting activities daily and, therefore, the quality of life. The application of Kinesio taping (KT) in patients with CP has emerged as a choice of adjunct treatment. Therefore the objective of this review was to evaluate the effectiveness of KT as an addition to conventional physiotherapy (CPT) interventions on posture, balance, and gait in spastic cerebral palsy.

Materials and Methods:
A bibliographic search was done in various databases. Only randomized controlled trials on KT in CP were included. The risk of bias in included studies was evaluated by using the RoB 2.0 tool. Downs and Black checklist was used to determine the overall quality of studies.

Results:
A total of five studies were eligible, out of which two studies reported a low risk of bias and three studies reported some concerns on RoB 2.0. The overall methodological quality of the studies ranged from fair to good. Out of five studies in three studies, KT was more effective as adjunct CPT than CPT alone on sitting posture, balance, and standing balance. In one study, KT was equally effective as ankle foot orthosis on gait. Lastly, one study showed a significant improvement with KT application over CPT alone, but the effects of neuromuscular electrical stimulation were more significant than KT on postural control and sitting.

Conclusion:
KT is a noninvasive, inexpensive, and compliant adjunct to physiotherapy in patients with spastic CP for better outcomes regarding posture, balance, and gait.
Personality Traits and Tinnitus Distress
Authors: Qi Min , Zhang Shuqi , Li Lingwei , Li Zhenzhi , Yin Gendi , Yuan Lianxiong , Fang Bixing , Gu Jing , Wang Xinyi , Zeng Xiangli , Li Zhicheng 
Published: December 2023

Background:
Due to the socio-cultural differences between China and other countries, which may affect the development of an individual’s personality and behavior, it is necessary to explore the relationship between personality traits and tinnitus distress in the context of China’s socio-cultural background.

Methods:
The Tinnitus Handicap Inventory and the Eysenck Personality Questionnaire Short Scale Chinese version were used to explore the influence of personality traits on tinnitus distress in Chinese patients with tinnitus.

Results:
The results were not entirely consistent with previous studies from other countries. First, extroversion was significantly higher in patients with bothersome tinnitus, both in acute and chronic conditions. Second, the personality traits that affected the patients with bothersome tinnitus were different in different conditions. Finally, the tridimensional personality structure, high psychoticism / normal extroversion / normal neuroticism, was significantly higher in people with bothersome tinnitus. Furthermore, the difference became more obvious with a prolonged disease course.

Conclusions:
This study suggested that the relationship between personality traits and tinnitus distress in Chinese patients with tinnitus was not the same as in other countries. “High psychoticism / normal extroversion / normal neuroticism” may be a risk factor for chronic bothersome tinnitus in China.
An unexpected case of nasolacrimal duct obstruction with dacryolith containing Pleurostomophora richardsiae
Authors: El-Jack Khalid , Naeem Fawaz T. , Chan Lilian , Briceño César A. 
Published: December 2023

Abstract
Here, we report a case of chronic dacryocystitis and nasolacrimal duct obstruction (NLDO) with dacryolith containing Pleurostomophora richardsiae and Candida albicans in a female patient. She presented with 10 years of epiphora and 1 year of a recurring cyst near her right medial canthus. On examination, the patient was found to have a dilated lacrimal sac and evidence of NLDO. The patient underwent dacryocystorhinostomy, during which a dacryolith was removed, and subsequent microbiological analysis revealed the presence of P. richardsiae and C. albicans. To our knowledge, there are only two prior case reports in the literature documenting P. richardsiae related to NLDO.
Short-term intraocular pressure changes after aflibercept (Eylea©) intravitreal injections: Which factors should be considered?
Authors: Barbosa Renato Correia , Gonçalves Rita , Basto Rita , Viana Ana Rita , Tenedorio Paula 
Published: December 2023

Abstract

Introduction:
To measure and interpret short-term pressure variation after intravitreal injections (IVIs) of the antivascular endothelial growth factor drug aflibercept (Eylea©), and to identify variables and risk factors for increased pressure spikes.

Materials and Methods:
A prospective study was conducted on 103 eyes treated with intravitreal aflibercept (Eylea©). Intraocular pressure (IOP) was measured using the Icare®cTA01i tonometer immediately before and 1, 5, and 20 min after the procedure. Patient data were reviewed according to age, gender, diagnostic, phakic status, and glaucoma history.

Results:
Mean values of IOP before and 1, 5, and 20 min after the injection were 14.89 (±4.19) mmHg, 36.77 (±11.46) mmHg, 24.17 (±7.81) mmHg, and 16.54 (±5.26) mmHg, respectively. Significant differences were found in patients with a history of glaucoma, 20 min after the injection (P = 0.006). No significant differences were found between phakic and pseudophakic patients (P = 0.379).

Discussion and Conclusion:
More than three-quarters (76.7%) of the patients had an IOP higher than 30 mmHg 1 min after the injection. Almost half (47.57%) had an IOP higher than 40 mmHg. Phakic status did not seem to affect IOP after IVIs. Patients with a history of glaucoma may have a slower postinjection IOP decrease, shown by a mean IOP difference of 3.72 mmHg, 20 min after the injections. These patients are at a greater risk for progressive worsening of their glaucoma due to repeated IOP spikes after multiple IVIs. IOP should be closely monitored, and a low threshold for optimizing topical therapy should be established.
Good practices in simulation-based education in Ophthalmology – A thematic series. An initiative of the Simulation Subcommittee of the Ophthalmology Foundation Part I: Initiating and maintaining simulation-based training
Authors: Filipe Helena Prior , Grau Arturo , Musa Pablo , Thomsen Ann Sofia Skou , Clements John , Luciano Andreas Di , Lansingh Van , Ng Danny Siu-Chun , Labuschagne Mathys 
Published: December 2023

Abstract
Understanding how learning occurs is useful to inform instructional design and create more engaging and enjoyable learning environments. In this first article of a quartet thematic series on good practices in simulation-based training, we reviewed several learning theories that can illuminate learning by simulation. We describe how to develop and improve a simulation center considering a holistic approach. Finally, we conclude by supporting the concept of developing mastery in high-quality education by simulation as a natural ally for accreditation acknowledgment and demonstrable impact on educational and clinical outcomes with patient safety and better care.
Study of the association of lipocalin-1 in tears with the progression of diabetic retinopathy: Cross-sectional comparative study
Authors: Bhatia Rahul , Gautam Priyanka , Sharma Isha , Beri Nitika , Sahu Pramod Kumar , Das Gopak K 
Published: December 2023

Abstract

Context:
Biomarkers are measurable indicators of a biological process or condition that can aid in the diagnosis and management of diseases. We have explored the role of Lipocalin in predicting the progression of DR.

Aims:
The aim of this study was to compare the levels of lipocalin-1 (LCN1) in tears of patients with established diabetic retinopathy (DR) with patients without DR and to evaluate the clinical application of LCN1 as a biomarker which can predict the progression of DR.

Settings and Design:
This cross-sectional comparative study was conducted in the outpatient setting of the department of ophthalmology and the department of biochemistry.

Subjects and Methods:
The tear samples obtained from the patients with no DR, nonproliferative DR (NPDR), and PDR were analyzed using enzyme-linked immunosorbent assay, and levels of LCN1 were compared among the three groups.

Statistical Analysis Used:
All data were expressed as mean ± standard deviation, and all significant differences were analyzed using the Chi-square test for qualitative data and one-way analysis of variance for quantitative data with the SPSS 20.0 statistical software data analysis (SPSS, Chicago, IL, USA) to compare the means between the three groups.

Results:
Levels of LCN1 were significantly reduced in patients with DR when compared to levels in patients with no DR. The expression levels might be useful as a diagnostic and prognostic biomarker of DR.

Conclusion:
In our study, it was observed that the levels of LCN 1 in tears of patients with Proliferative Diabetic Retinopathy was decreased as compared to the levels of LCN 1 in tears of Non-Proliferative Diabetic Retinopathy and cases with no Diabetes Retinopathy. Establishment of this correlation has possible implications for screening of Diabetic Retinopathy in patients of Diabetes. However, larger studies with greater number of cases are needed to establish the definitive role of LCN1, as a screening tool for Diabetic Retinopathy.
Ocular Complications Secondary to Common Malpractices Followed in Rural Areas – A Tertiary Care Centre Study
Authors: Spoorthy S , Sharanya S N 
Published: December 2023

Aim of the Study:
To assess the ocular complications associated with common malpractices done in rural area.

Materials and Method:
A hospital based observational, cross section study. In a year, 38 patients found to have undergone ocular malpractices after considering inclusion and exclusion criteria. Detailed clinical history with ophthalmic examination was done.

Results:
Out of 38 patients who underwent malpractices, 28 (73.7%) had history of quackery, 4 (10.5%) had history of wrong medicine usage, 3 (7.8%) had history of traditional medicine usage and 3 (7.8%) had multiple causes. Commonest complaint was stone or foreign body removal by quacks using grass. The common complications noted were periorbital skinreaction (10.5%), conjunctivitis(42.1%), keratoconjunctivitis (13.1%), sight threatening corneal ulcers (28.9%), old corneal opacity (2.6%), panophthalmitis (2.6%).

Conclusion:
Quackery, traditional medicine usage, wrong drugs usage are the common ocular malpractices prevalent in rural India. Often, they are associated with sight threatening complications. Public awareness is needed to decrease the harmful effects arising from such practices
Evaluation of YouTube Videos for Information and Education on Amblyopia
Authors: Dhillon Hennaav Kaur , Jha Ujjwal Prakash , Goel Itisha , Singh Rohan Bir , Ichhpujani Parul , Parmar Uday Pratap Singh , Gupta Gayana 
Published: December 2023

Background:
YouTube is a popular social media platform accessed by people to obtain relevant health and disease-related information. The purpose of this study was to evaluate YouTube videos as a source of information on amblyopia.

Material and Methods:
In this prospective, cross-sectional study a YouTube search was conducted using three keywords, ‘Lazy eye’, ‘amblyopia’ and ‘Lazy eye treatment’ on 26th January, 2022. Video quality assessment was done using Modified DISCERN (mDISCERN), Global Quality Score and the Health on the Net Foundation Code of Conduct (HONcode) scale. Video content was analysed as a health professional and non-health professional, video length, release date, daily view count and Video Power Index. The relationship between the groups and video quality was evaluated.

Results:
Of the 300 initial videos investigated for the study, 219 videos met the inclusion criteria and were subjected to statistical analysis. Nearly 50% of videos contained content related to medical education. More than half of the videos analysed (130; 59.36%) were uploaded by healthcare professionals (HCPs). The mDISCERN mean ± SD score for the videos was 2.65 ± 1.24, for the Journal of the American Medical Association (JAMA) scoring was 2.37 ± 1.02 and for the HONcode was 3.72 ± 1.75. All scoring systems were better for HCPs as compared with non-healthcare professionals (NHCPs).

Conclusion:
A wide variety of information about amblyopia is available on YouTube™. Videos uploaded by NHCP had suboptimal flow as well as information of limited use to patients.
Use of Supervision Data to Improve Quality of Care for Malaria in Pregnancy: Experience in Six African Countries
Authors: Wolf Katherine , Mostel Jadmin , Oseni Lolade , Gomez Patricia , Kibuka Tabitha , Emerson Courtney , Gutman Julie R. , Malpass Ashley , Youll Susan , Mukamba Jean Yves , Tchinda Meli Eric , Achu Dorothy , Tjek Paul , Assa Jean Louis , Silue Mamadou , Tanoh Méa Antoine , Kokrasset-Yah Colette , Babanawo Felicia , Asiedu Amos , Komey Mildred , Boateng Paul , Mabiria Maureen , Ngindu Augustine , Njiru Peter , Omar Ahmeddin Hassan , Sidibe Fatoumata A. , Diallo Chebou , Kamate Beh , Kone Aissata , Elisha Sanoussi , Maiga Arouna Djibrilla , Mayaki Alzouma Ibrahim , Tidjani Issa Gana Fati , Tetteh Gladys 
Published: December 2023

ABSTRACT.
Malaria in pregnancy (MiP) intervention coverage, especially intermittent preventive treatment in pregnancy (IPTp), lags behind other global malaria indicators. In 2020, across Africa, only 32% of eligible pregnant women received at least three IPTp doses, despite high antenatal care attendance. We conducted a secondary analysis of data collected during Outreach Training and Supportive Supervision visits from 2019 to 2020 to assess quality of care and explore factors contributing to providers’ competence in providing IPTp, insecticide-treated nets, malaria case management, and respectful maternity care. Data were collected during observations of provider–patient interactions in six countries (Cameroon, Cote d’Ivoire, Ghana, Kenya, Mali, and Niger). Competency scores (i.e., composite scores of supervisory checklist observations) were calculated across three domains: MiP prevention, MiP treatment, and respectful maternity care. Scores are used to understand drivers of competency, rather than to assess individual health worker performance. Country-specific multilinear regressions were used to assess how competency score was influenced by commodity availability, training, provider gender and cadre, job aid availability, and facility type. Average competency scores varied across countries: prevention (44–90%), treatment (78–90%), and respectful maternity care (53–93%). The relative association of each factor with competency score varied. Commodity availability, training, and access to job aids correlated positively with competency in multiple countries. To improve MiP service quality, equitable access to training opportunities for different cadres, targeted training, and access to job aids and guidelines should be available for providers. Collection and analysis of routine supervision data can support tailored actions to improve quality MiP services.
Thắt động mạch tử cung trong phẫu thuật nội soi cắt tử cung: nghiên cứu tổng hợp y văn và phân tích gộp
Authors: Hoàng Trọng Nam , Cao Ngọc Thành , Trương Quang Vinh 
Published: December 2023

Đặt vấn đề: Phẫu thuật nội soi cắt tử cung ngày nay đã được ủng hộ như một biện pháp điều trị tiêu chuẩn. Kỹ thuật phẫu thuật nội soi thắt động mạch tử cung khi cắt tử cung thay thế cho phương pháp truyền thống, đã được đề xuất và có thể mang lại những lợi ích quan trọng cho cả bệnh nhân và bác sĩ phẫu thuật. Tuy nhiên, sự lựa chọn này hoàn toàn dựa trên ý kiến v à sở thích của bác sĩ phẫu thuật. Bằng chứng sẵn có so sánh hai phương pháp này còn hạn chế, và tính ưu việt của phương pháp này so với phương pháp kia là không rõ ràng. Vì vậy, chúng tôi tiến hành phân tích tổng hợp để so sánh hiệu quả của hai phương pháp này.
Đối tượng và phương pháp nghiên cứu: Phương pháp tổng hợp tài liệu có hệ thống: Tuân thủ các Mục Báo cáo Ưu tiên cho Đánh giá Hệ thống và Phân tích Tổng hợp (PRISMA) hướng dẫn, ấn bản 2020, tìm kiếm có hệ thống được thực hiện bằng PubMed (sắp xếp theo gần đây nhất), Cochrane, Semantic scholar sử dụng Các thuật ngữ MeSH (nếu có) và các từ khóa cho các khái niệm “Uterine Artery ligation” hoặc “Uterine Artery occlusion” hoặc “Uterine Artery coagulation” và “laparoscopic hysterectomy”. Các tiêu chí chọn bệnh: dựa trên phân tích Patient/Population, Intervention, Comparator, Outcome, Study (PICOS).
Kết quả: Trọng lượng tử cung giữa hai nhóm thắt động mạch tử cung trong phẫu thuật nội soi cắt tử cung và không thắt động mạch tử cung không khác biệt giữa hai nhóm với z = 0,7304, p = 0,4652. So sánh sự khác biệt chỉ định giữa hai nhóm: u xơ tử cung (kết quả trung bình không khác biệt đáng kể so với 0 (z = 0,2412, p = 0,8094, I² = 29,9%)), adenomyosis (kết quả trung bình không khác biệt đáng kể so với 0 (z = -0,4103, p = 0,6816, I² = 0%), chảy máu bất thường buồng tử cung (, kết quả trung bình không khác biệt đáng kể so với 0 (z = -0,6851, p = 0,4933, I² = 0%). Thời gian phẫu thuật giữa hai nhóm: kết quả trung bình không khác biệt đáng kể so với 0 (z = -1,0054, p = 0,3147, I² = 88%). Lượng máu mất trong nhóm thắt động mạch tử cung ít hơn so với nhóm không thắt động mạch tử cung với z = -10,0632, p < 0,0001, I² = 93%. Không có sự thay đổi Hb giữa hai nhóm với (z = 0,7125, p = 0,4761, I² = 0%). Không có sự biệt về biến chứng chung giữa hai nhóm nghiên cứu với (z = -0,9315, p = 0,3516, I² = 0%).
Kết luận: Thắt động mạch tử cung đồng thời trong phẫu thuật nội soi cắt tử cung hoàn toàn giúp giảm lượng máu mất. Ngoài ra, không làm tăng nguy cơ biến chứng và không kéo dài thời gian phẫu thuật.
Đánh giá sự hài lòng của bà mẹ về quá trình chăm sóc trong và sau sinh tại Bệnh viện Trường Đại học Y - Dược Huế
Authors: Nguyễn Thị Thu Phương , Đặng Thị Loan , Hoàng Thế Hiệp , Nguyễn Thị Anh Phương 
Published: December 2023

Mục tiêu: Đánh giá sự hài lòng của bà mẹ về quá trình chăm sóc trong và sau sinh tại Bệnh viện Trường Đại học Y - Dược Huế.
Đối tượng và phương pháp: Nghiên cứu được tiến hành theo phương pháp mô tả cắt ngang trên 572 sản phụ mang thai đủ tháng và đến sinh tại Khoa Phụ sản, Bệnh viện Trường Đại học Y - Dược Huế.
Kết quả: Độ tuổi trung bình là 27,4 ± 5,3; Tỷ lệ hài lòng chung của bà mẹ về quá trình chăm sóc trong và sau sinh chiếm 81,8% và không hài lòng chiếm 18,2%. Trong đó, tỷ lệ hài lòng về mức độ tự tin chăm sóc trẻ; Chăm sóc sau sinh; Cung cấp dịch vụ; Môi trường, cơ sở vật chất; Tôn trọng quyền riêng tư và Chăm sóc khi chuyển dạ và sinh lần lượt là 79,7%, 84,3%, 85,5%, 85,7%, 93,4%, 88,6%. Điểm trung bình của hài lòng chung 4,44 ± 0,61.
Kết luận: Sự hài lòng của bà mẹ về quá trình chăm sóc trong và sau sinh tại Bệnh viện Trường Đại học Y - Dược Huế với tỷ lệ hài lòng 81,8%.
Vai trò của tiểu cầu máu cuống rốn trong tiên lượng bệnh nặng ở trẻ sơ sinh đẻ non
Authors: Tôn Nữ Vân Anh , Huỳnh Thị Minh Lý 
Published: December 2023

Mục tiêu: Đánh giá vai trò của tiểu cầu máu cuống rốn trong tiên lượng bệnh nặng ở trẻ sơ sinh đẻ non.
Phương pháp và đối tượng nghiên cứu: Nghiên cứu mô tả và theo dõi dọc có so sánh nhóm chứng. Đối tượng nghiên cứu bao gồm các trẻ sơ sinh đẻ non < 37 tuần và được làm xét nghiệm công thức máu cuống rốn ngay sau sinh tại Khoa Sản - Nhi sơ sinh, Bệnh viện Trường Đại học Y - Dược Huế từ tháng 04/2021 đến 07/2023. Nhóm bệnh (non tháng bệnh lý) bao gồm 38 trẻ có mắc bệnh lý trong giai đoạn sơ sinh sớm và được điều trị tại Nhi sơ sinh. Nhóm chứng (non tháng bình thường) bao gồm 33 trẻ không mắc bệnh lý trong giai đoạn sơ sinh sớm và được nằm cùng mẹ tại khoa Sản. Qua thăm khám lâm sàng, theo dõi trong giai đoạn sơ sinh sớm và so sánh số lượng tiểu cầu máu cuống rốn của hai nhóm.
Kết quả: Nghiên cứu ghi nhận số lượng tiểu cầu của nhóm trẻ có cân nặng < 2500 g thấp hơn nhóm trẻ có cân nặng ≥ 2500 g lần lượt là 129.000/mm3 và 189.500/mm3 (p < 0,05); Chưa thấy sự khác biệt của số lượng tiểu cầu máu cuống rốn về các yếu tố như giới tính, phương pháp sinh, tuổi thai. Số lượng tiểu cầu máu cuống rốn của nhóm trẻ sơ sinh non tháng bệnh lý thấp hơn nhóm non tháng bình thường với số lượng lần lượt là 115.500/mm3 và 222.400/mm3 (p < 0,05); số lượng tiểu cầu máu cuống rốn giảm < 150.000/mm3 có nguy cơ mắc bệnh lý cao gấp 3,94 lần so với những trẻ có tiểu cầu ≥ 150.000/mm3 (p < 0,05).
Kết luận: Trẻ sơ sinh non tháng bệnh lý có số lượng tiểu cầu máu cuống rốn thấp hơn nhóm non tháng bình thường. Tiểu cầu máu cuống rốn được xem là một yếu tố tiên lượng bệnh nặng ở trẻ sơ sinh đẻ non. Đây là một xét nghiệm đơn giản, có thể áp dụng rộng rãi ở các cơ sở y tế.
A RETROSPECTIVE STUDY OF MEDICATION-RELATED OSTEONECROSIS OF THE JAW IN MULTIPLE MYELOMA PATIENTS
Authors: Savio Melzer Rafaela , Santos-Rodrigues Danielle , Guebur Maria Isabela , Sassi Laurindo Moacir , Ignácio Sérgio Aparecido , Batista Rodrigues Johann Aline Cristina 
Published: December 2023

Background: Multiple myeloma is a malignant hematological neoplasm, whose treatment involves the use of bisphosphonates and monoclonal antibodies, which may be related to medication-related osteonecrosis.
Objective: The present study aims to verify the presence of medication-related osteonecrosis of the jaws in patients undergoing treatment for multiple myeloma who used chemotherapy associated or not with bisphosphonates and/or monoclonal antibodies. Beyond this, to trace the epidemiological profile of patients who developed medication-related osteonecrosis.
Methods: This 15-year retrospective observational study consisted of evaluating 461 medical records of patients diagnosed with multiple myeloma from the oncology referral hospital in Brazil, Erasto Gaertner Hospital.
Results: It was observed that both the group that developed osteonecrosis and the group that did not develop, no statistically significant difference when evaluated separately regarding sex, bone marrow transplant and ethnicity. However, the group with osteonecrosis showed a higher frequency in the use of bisphosphonates, did not progress to death, were non-smokers, the mandible was the most affected anatomical site, and the type of bone exposure spontaneously was the most observed.
Conclusions: The combined use of pentoxifylline and tocopherol was responsible for the successful resolution of cases of medication-related osteonecrosis. Isolating the underlying disease allowed for greater control and knowledge regarding the medications used for the treatment of medication-related osteonecrosis.