bluuebunny/crossref_metadata_2025_split huggingface dataset:
The 10-Word Auditory Verbal Learning Test and Vocabulary Performance in 4- and 5-Year-Old Children
Authors: Kasperek Ann , Kingma Annet , de Aguiar Vânia 
Published: September 2023

Background:
Understanding the different factors that determine vocabulary development in young children is essential for the diagnosis and rehabilitation of language disorders in children. Language development is closely related to other cognitive processes such as auditory verbal learning and memory. This research focuses on the development of a novel auditory verbal learning test (AVLT) for 4- and 5-year-old children within the Dutch population. This new test is an adaptation of the common AVLT for both older children and adults, usually including a list of 15 words. Considering the lower attention span and limited executive functioning in young children, the word list of this new instrument is reduced to 10 words. Besides, a second recognition form has been developed to improve the ability to distinguish between possible underlying learning and memory deficits.

Method:
Ninety-five preschool children (ages 4;0–5;12 [years;months]) were tested with this new AVLT 10-word test for kids (10WT-K), yielding different measures of verbal auditory memory. Forty-eight of 95 children received a recognition task with semantically unrelated items, and 47 of 95 received a recognition task with semantically related items. Three additional language skills were assessed to establish test validation: receptive and expressive vocabulary performance and nonword repetition. Outcome of the 10WT-K was related to scores on the language measures.

Results:
Positive correlations were found between the total score of the 10WT-K and all three aforementioned language skills. We found no correlations between frequency of error types (intrusions and repetitions) and language measures. Furthermore, children who were administered the recognition list with semantically related items showed fewer correct answers and more false-positive and false-negative responses than children who received a recognition list with semantically unrelated items.

Conclusions:
The 10WT-K for young children can be used to (a) measure different aspects of auditory verbal learning and memory, (b) clarify the nature of possible verbal learning difficulties, and (c) identify a possible nature of language disorders. The word recognition task tested with semantically related items provides a more accurate measurement of individual differences, namely, in distinguishing retrieval and storage abilities. The significant relation found between auditory verbal short-term memory capacity and vocabulary performance in preschool children is a first step toward establishing test validity.
Gender Differences in Self-Reported Oral Health–Related Quality of Life Among Older Men and Women at Two Midwest Senior Centers
Authors: Kanade Ashwini , Strother-Garcia Kristina , Parham Douglas F. 
Published: September 2023

Purpose:
The purpose of this study was to assess the differences in functional, psychosocial, and pain-related consequences of oral health among older men and women at two Midwest senior centers.

Method:
The Geriatric Oral Health Assessment Index (GOHAI) was used to assess self-reported oral health–related quality of life (OHRQoL) among older men and women at two Midwest senior centers. Researchers also collected demographic information, including age, gender, marital status, level of education, annual income, and ethnicity.

Results:
Older women reported significantly lower overall OHRQoL than men did, and this difference was not better explained as being due to differences in annual income or marital status. Furthermore, women scored significantly lower on the Physical Functioning and Psychosocial Functioning subscales of the GOHAI, while women also had lower average scores on the Pain/Discomfort subscale. This difference did not reach statistical significance.

Conclusions:
Older women were reportedly more negatively impacted by OHRQoL issues than older men. Women reported significantly lower levels of physical and psychosocial functioning due to oral health problems. Data regarding gender differences in oral health related pain and discomfort were inconclusive. Further research is needed to examine this question, as well as to determine the reasons why women seem to experience lower OHRQoL than men do in old age.
IDBNet: Improved differentiable binarisation network for natural scene text detection
Authors: Zhang Zhijia , Shao Yiming , Wang Ligang , Li Haixing , Liu Yunpeng 
Published: September 2023

AbstractThe text in the natural scene can express rich semantic information, which helps people understand and analyse daily things. This paper focuses on the problems of discrete text spatial distribution and variable text geometric size in natural scenes with complex backgrounds and proposes an end‐to‐end natural scene text detection method based on DBNet. The authors first use IResNet as the backbone network, which does not increase network parameters while retaining more text features. Furthermore, a module with Transformer is introduced in the feature extraction stage to strengthen the correlation between high‐level feature pixels. Then, the authors add a spatial pyramid pooling structure in the end of feature extraction, which realises the combination of local and global features, enriches the expressive ability of feature maps, and alleviates the detection limitations caused by the geometric size of features. Finally, to better integrate the features of each level, a dual attention module is embedded after multi‐scale feature fusion. Extensive experiments on the MSRA‐TD500, CTW1500, ICDAR2015, and MLT2017 data set are conducted. The results showed that IDBNet can improve the average precision, recall, and F‐measure of a text compared with the state of art text detection methods and has higher predictive ability and practicability.
High performance image steganography integrating IWT and Hamming code within secret sharing
Authors: Saeidi Zahra , Yazdi Ameneh , Mashhadi Samaneh , Hadian Masoud , Gutub Adnan 
Published: September 2023

AbstractSteganography and secret sharing are schemes to increase the security of private information against attackers. Steganography emphasizes secrecy while secret sharing distributes the secret key in shares that are conditionally classified to reconstruct the original secret. This paper introduces a counting‐based secret sharing scheme that aims to reduce the computational complexity for longer keys, thereby providing a practical steganographic approach for efficient sharing. The scheme integrates counting‐based secret sharing with integer wavelet transform (IWT) and steganography. The subscriptions created using the Hamming code are embedded in the cover image. Using this method, IWT significantly reduces the occurrence of common rounding errors. As a result, secret key extraction becomes very accurate and eliminates the need to access the original images. This design, using secret sharing based on counting, not only has simplicity and efficiency, but also features such as flexibility, scalability, and lack of central authority. In addition, high‐quality steganography was obtained for keys with lengths of 64, 256, 512, 1024, and 3072, showing an average PSNR=80.11 in different color images. This outstanding performance makes it a highly efficient alternative to previous designs, representing a groundbreaking contribution with significant public interest in the field.
Capacity evaluation of hydropower for accommodating wind‐photovoltaic power generation in the dry season
Authors: Zhou Yerong , Zhang Yangbo , Zhu Yanmei , Huang Weibin , Chen Shijun , Ma Guangwen 
Published: September 2023

AbstractConsidering that the benefits of hydropower stations from regulating and consuming new energy are restricted during the dry season due to the inadequate regulation capacity, this paper focuses on the accommodation capacity evaluation of hydropower for wind‐ photovoltaic (PV, for short) power generation in different supply‐grid‐load conditions. First, the factors that influence hydropower stations' accommodation capacity were initially examined in this study, in terms of power supply, power grid, and load. Then, two new indices, namely the regulatory factor of installed capacity and the regulatory factor of electric quantity, were put forward to evaluate the capacity of hydropower for accommodating wind‐PV. To reduce the peak regulation burden on the power grid and encourage the consumption of clean energy, a two‐objective optimization model with maximum source‐load matching and clean energy consumption was devised. And a two‐tier binary algorithm and progressive optimization coupled strategy was proposed to solve the model. Finally, the cascade hydropower stations in the north Panxi section of the Yalong River and the surrounding wind farm and PV power stations were taken as examples to examine the sensitivity of the factors. The results show that with each 5% increase in the regulatory electric quantity, the regulatable installed wind‐PV capacity and consumable wind‐PV electric quantity were increased by 7.57% and 8.21%, respectively, rank only second to transmission capacity. Considering the large investment required for transmission channel expansion, this result reveals that the most effective and economical way to promote wind‐PV consumption is to increase the regulated electric quantity of hydropower stations in the river basin.
Akute Ischämie bei Tumorpatienten: Pathogenese, Therapie und Prävention
Authors: Argyriou Angeliki , Shehada Yousef , Torsello Giovanni , Tsilimparis Nikolaos , Stana Jan , Stavroulakis Konstantinos , Rantner Barbara 
Published: September 2023

ZusammenfassungArterielle Thromboembolien machen ca. 10–30% aller tumorassoziierten thromboembolischen Komplikationen aus 1 und haben trotz Fortschritten in der medikamentösen und operativen Therapie der akuten peripheren Ischämie noch immer eine beträchtliche Mortalität bzw. Morbidität zur
Folge 2. Der vorliegende Beitrag schildert Pathophysiologie, Diagnostik und neueste Therapiemöglichkeiten der tumorassoziierten akuten Extremitätenischämie.
The fate of ‘pseudo-’ words
Authors: Van Goethem Kristel , Norde Muriel , Masini Francesca 
Published: September 2023

Abstract
The present study examines the fate of the neoclassical combining form pseudo- in eight European languages, belonging to Germanic (Danish, Dutch, English, German and Swedish) and Romance (French, Italian, Spanish). In order to gain a better understanding of the synchronic morphological behaviour and productivity of pseudo- words in these languages, we carry out a cross-linguistic corpus analysis and compare the morphological and distributional properties of pseudo-. We also analyse its debonding behaviour and categorical flexibility in the set of languages and correlate this property with its productivity. The results of the corpus study are discussed against the typological background of the so-called Germanic and Romance Sandwiches.
Investigating cognitive processes during writing tests
Authors: Guggenbichler Elisa , Eberharter Kathrin , Kremmel Benjamin 
Published: September 2023

The purpose of this chapter is to critically discuss
some of the key issues when investigating writing processes for the purposes
of foreign language assessment research – a branch of research that
currently tends to triangulate synchronous observational data (e.g., eye
tracking, keystroke logging) with asynchronous data from stimulated verbal
recalls or text analysis. We will discuss a range of methodological
considerations that should be taken into account when researching foreign
language writing processes in the context of language tests and beyond. We
will exemplify and critically discuss key issues related to three of the
methods predominantly used in this strand of research: eye tracking,
keystroke logging, and stimulated recalls. We will illustrate these issues
and decision-making processes at the various stages of research by
critically reflecting on the lessons learned from two research projects of
this kind conducted by the authors.
Structural analysis of novel drug targets for mitigation of Pseudomonas aeruginosa biofilms
Authors: Ghosh Moumita , Raghav Shikha , Ghosh Puja , Maity Swagatam , Mohela Kavery , Jain Deepti 
Published: September 2023

Abstract
Pseudomonas aeruginosa is an opportunistic human pathogen responsible for acute and chronic, hard to treat infections. Persistence of P. aeruginosa is due to its ability to develop into biofilms, which are sessile bacterial communities adhered to substratum and encapsulated in layers of self-produced exopolysaccharides. These biofilms provide enhanced protection from the host immune system and resilience towards antibiotics, which poses a challenge for treatment. Various strategies have been expended for combating biofilms, which involve inhibiting biofilm formation or promoting their dispersal. The current remediation approaches offer some hope for clinical usage, however, treatment and eradication of preformed biofilms is still a challenge. Thus, identifying novel targets and understanding the detailed mechanism of biofilm regulation becomes imperative. Structure-based drug discovery (SBDD) provides a powerful tool that exploits the knowledge of atomic resolution details of the targets to search for high affinity ligands. This review describes the available structural information on the putative target protein structures that can be utilized for high throughput in silico drug discovery against P. aeruginosa biofilms. Integrating available structural information on the target proteins in readily accessible format will accelerate the process of drug discovery.
Path Dependency in Physician Decisions
Authors: Jin Lawrence , Tang Rui , Ye Han , Yi Junjian , Zhong Songfa 
Published: September 2023

Abstract
We examine path dependency in physician decisions in an emergency department setting, and find that physicians’ treatment decisions for the current and previous patients are positively correlated. We show that the positive autocorrelation is higher when the current patient is of greater medical uncertainty or more similar to the previous patient in terms of observed characteristics and when the physician is less experienced or more fatigued. We then show that these patterns are highly consistent with the memory and attention model, whereby the physician’s current decision is anchored to her previous decision. The results from both reduced-form analyses and structural estimations provide further support for the importance of memory and attention in physician decision-making.
chi‐miR‐130b‐3p regulates the ZEA‐induced oxidative stress damage through the KEAP1/NRF2 signaling pathway by targeting SESN2 in goat GCs
Authors: Liu Liang , Ma Jianyu , Wei Zongyou , Yang Yingnan , Liu Zifei , Li Dongxu , Yu Xiaoqing , Fan Yixuan , Wang Feng , Wan Yongjie 
Published: September 2023

AbstractAs a dominant mycotoxin, zearalenone (ZEA) has attracted extensive attention due to its estrogen‐like effect and oxidative stress damage in cells. In order to find a way to relieve cell oxidative stress damage caused by ZEA, we treated goat granulosa cells (GCs) with ZEA and did a whole transcriptome sequencing. The results showed that the expression level of Sesterin2 (SESN2) was promoted extremely significantly in the ZEA group (p < .01). In addition, our research demonstrated that SESN2 could regulate oxidative stress level in GCs through Recombinant Kelch Like ECH Associated Protein 1 (KEAP1)/Nuclear factor erythroid 2‐related factor 2 (NRF2) signaling pathway. The overexpression of SESN2 could reduce the oxidative damage, whereas knockdown of SESN2 would aggravate the oxidative damage caused by ZEA. What's more, microRNA (miRNA) chi‐miR‐130b‐3p can bind to SESN2 3′‐untranslated region (3′UTR) to regulate the expression of SESN2. The mimics/inhibition of chi‐miR‐130b‐3p would have an effect on oxidative damage triggered by ZEA in GCs as well. In summary, these results elucidate a new pathway by which chi‐miR‐130b‐3p affects the KEAP1/NRF2 pathway in GCs by modulating SESN2 expression in response to ZEA‐induced oxidative stress damage.
GDF-15 (a biomarker for metformin) and the risk of COVID-19: A two-sample Mendelian randomization study
Authors: Wang Ya , Yao Peishan , Li Kai , Qin Shanyu 
Published: September 2023

Background:
Regarding the impact of metformin on COVID-19, there are currently varying opinions from multiple studies. Growth differentiation factor 15 (GDF-15) is a biomarker of metformin use and dosage, and we used two-sample Mendelian randomization (MR) to assess the causal effect of GDF-15 (metformin) on COVID-19 susceptibility, hospitalization, and severe COVID-19, thereby guiding the selection of glucose-lowering agents for diabetic patients during the COVID-19 pandemic.

Methods:
Two sets of genetic tools were utilized for MR analysis, derived from publicly available genetic data. The first set was GDF-15 genome-wide association study (GWAS) data from a study with 5440 participants, while the second set was COVID-19 GWAS data from the Host Genetics Initiative (HGI) GWAS meta-analysis. The primary method used to assess causal effects was random effects inverse variance weighted estimation. Complementary methods included weighted median and MR-Egger analyses. Sensitivity analysis was performed using Cochran Q tests, MR-Egger intercept tests, MR-PRESSO, leave-one-out analyses, and funnel plots.

Results:
GDF-15 increased the risk of severe COVID-19 in patients (OR = 1.10, 95% CI 1.03–1.19; P = .006); there was no causal effect of GDF-15 on hospitalization for COVID-19 (OR = 1.02, 95% CI 0.96–1.07; P = .47) or susceptibility to COVID-19 in the general population (OR = 1.010, 95% CI 0.988–1.034; P = .354).

Conclusions:
Our study supports the notion that GDF-15 increases the risk of severe COVID-19 in patients. However, there is no causal relationship between GDF-15 and hospitalization or susceptibility to COVID-19.
Anti-amphiphysin antibody-associated paraneoplastic brainstem encephalitis with pruritus and dysphagia as the first symptoms: A case report
Authors: Wang Jin , Mi Xiaokun , Ban Feng , Zhao Jingxia 
Published: September 2023

Rationale:
Anti-amphiphysin antibodies are uncommonly detected in paraneoplastic neurologic syndromes (PNS), especially in patients with small cell lung cancer. Here, we report the first case of anti-amphiphysin antibody-associated PNS with pruritus and dysphagia as the first complaints.

Patient concerns:
The patient was a 58-year-old man who sought medical advice with a chief complaint of dysphagia and the lung occupancy. We found that he had developed progressive pruritus several months ago.

Diagnoses:
In the outer basal segment of the right lung lower lobe, PET-CT revealed small occupancies with hypermetabolism. Later, the pathology showed small cell lung cancer. And anti-amphiphysin antibodies were detected in serum. Above all, the patient’s symptoms improved significantly after antitumor treatment. Even neither of the 2 cranial enhancement MRIs showed any meaningful imaging signs, the above evidence could confirm the diagnosis of PNS.

Interventions:
The chemotherapy regimen was etoposide 0.1g d1-3+cisplatin 40 mg d1-3 (q3w). Paroxetine 20 mg/day was given to relieve the itching.

Outcomes:
After the treatment, the Watian water swallowing test dropped from grade 5 to grade 1, the intense itching also became tolerable.

Lessons:
Clinicians should consider diagnoses other than anxiety states or esophageal cancer in a patient with pruritus and dysphagia, such as PNS.
Synchronous occurrence of small cell lung cancer and primary rectal dedifferentiated liposarcoma with osteosarcomatous differentiation: A rare case report
Authors: Zheng Xiangyu , Wu Guangfeng , Fu Yongxian , Fan Rui 
Published: September 2023

Rationale:
Rectal dedifferentiated liposarcoma (DDL) and DDL with osteosarcomatous differentiation both are extremely unwonted. In addition, there are no reports of simultaneous DDL with osteosarcoma differentiation with small cell lung cancer (SCLC) to date. Therefore, it is imperative to alert clinicians and pathologists to this extremely rare and instructive synchronous tumor.

Patient concerns:
The patient was a 63-year-old male who presented with intermittent hematochezia and a swelling in the anus. Irregular masses were found on computed tomography (CT) examinations of the chest and abdomen respectively.

Diagnosis:
The final diagnosis of synchronous occurrence of SCLC and primary rectal DDL with osteosarcomatous differentiation was established by radiological, histological, immunohistochemical and molecular findings.

Interventions:
The patient underwent a puncture biopsy of the right lung mass and a complete resection of the rectal mass.

Outcomes:
The patient abandoned treatment, and multiple SCLC metastases appeared multiple metastasis 8 months after the operation. In the end, he expired suddenly due to severe cerebral hemorrhage caused by brain SCLC metastasis.

Lessons:
DDL with osteosarcoma differentiation is infrequent, and its accurate diagnosis is based on morphology, immunohistochemistry and the necessary molecular tests. In rare cases, DDL occurs concurrently with other malignancies and and will be a challenge for pathologists and clinicians at this time. Accordingly, a comprehensive examination to identify possible synchronous tumors is very important in clinical practice.
The impact of concomitant hepatitis C virus infection on liver and cardiovascular risks in patients with metabolic-associated fatty liver disease
Authors: Tsai Pei-Shan , Cheng Yu-Ming , Wang Chia-Chi , Kao Jia-Horng 
Published: September 2023

Background:
Chronic hepatitis C virus (HCV)-infected patients with hepatic steatosis are excluded from the diagnosis of nonalcoholic fatty liver disease (NAFLD). The new name and diagnostic criteria of metabolic-associated fatty liver disease (MAFLD) were proposed in 2020 to replace the original term NAFLD. The clinical outcome of MAFLD patients with concomitant chronic HCV infection requires further investigation.

Methods
The participants from Taiwan bio-bank cohort were included. MAFLD is defined as the presence of fatty liver, plus any of the following three conditions: overweight/obesity, type 2 diabetes, or metabolic dysfunction. The patients with positive anti-HCV were considered chronic HCV infections. The severity of liver fibrosis was determined using the fibrosis-4 index and NAFLD fibrosis score (NFS). The risk of cardiovascular disease (CVD) was assessed using intima-media thickness (IMT) or plaques of carotid duplex ultrasound.

Results
A total of 18 907 participants (age 55.79 ± 10.42; males 31.9%) were included for final analysis. The prevalence of MAFLD and chronic HCV infections were 39.2% and 2.6%, respectively. According to the status of MAFLD and chronic HCV infection, they were distributed to four groups: ‘dual etiology group’, ‘MAFLD alone’, ‘HCV alone’, and healthy controls. Compared with the ‘MAFLD alone’ group, the ‘dual etiology’ group had a lower frequency of the male sex, reduced levels of serum triglyceride, total cholesterol, and LDL; but overall older age, a higher percentage of hypertension history. In addition, they had higher levels of serum aspartate aminotransferase, fibrosis-4 index, and NFS; but no difference in levels of alanine aminotransferase, gamma-glutamyl transferase, fatty liver index, IMT, and the percentage of carotid plaques. Using binary logistic regression, chronic HCV infection was associated with more severe liver fibrosis, but not with carotid plaques in MAFLD patients.

Conclusion
MAFLD patients with concomitant HCV infection, a specific phenotype of MAFLD may include a higher risk of advanced liver fibrosis, but a similar risk of atherosclerotic cardiovascular disease compared to those without.