bluuebunny/crossref_metadata_2025_split huggingface dataset:
Carbon-neutral power system enabled e-kerosene production in Brazil in 2050
Authors: Deng Ying , Cao Karl-Kiên , Wetzel Manuel , Hu Wenxuan , Jochem Patrick 
Published: December 2023

AbstractRich in renewable resources, extensive acreage, and bioenergy expertise, Brazil, however, has no established strategies for sustainable aviation fuels, particularly e-kerosene. We extend the lens from the often-studied economic feasibility of individual e-kerosene supply chains to a system-wide perspective. Employing energy system analyses, we examine the integration of e-kerosene production into Brazil’s national energy supplies. We introduce PyPSA-Brazil, an open-source energy system optimisation model grounded in public data. This model integrates e-kerosene production and offers granular spatial resolution, enabling federal-level informed decisions on infrastructure locations and enhancing transparency in Brazilian energy supply scenarios. Our findings indicate that incorporating e-kerosene production can bolster system efficiency as Brazil targets a carbon-neutral electricity supply by 2050. The share of e-kerosene in meeting kerosene demand fluctuates between 2.7 and 51.1%, with production costs varying from 113.3 to 227.3 €/MWh. These costs are influenced by factors such as biokerosene costs, carbon pricing, and export aspirations. Our findings are relevant for Brazilian policymakers championing aviation sustainability and offer a framework for other countries envisioning carbon-neutral e-kerosene production and export.
Gene expression alterations predict the pathological complete response in triple-negative breast cancer exploratory analysis of the NACATRINE trial
Authors: Freitas Ana Julia Aguiar , Nunes Caroline Rocha , Mano Max Senna , Causin Rhafaela Lima , Santana Iara Viana Vidigal , de Oliveira Marco Antonio , Calfa Stéphanie , Silveira Henrique César Santejo , de Pádua Souza Cristiano , Marques Márcia Maria Chiquitelli 
Published: December 2023

AbstractThis exploratory analysis of the Neoadjuvant Carboplatin in Triple Negative Breast Cancer (NACATRINE) study aimed to identify the biomarkers of pathological complete response (pCR) in patients with triple-negative breast cancer (TNBC) treated with neoadjuvant chemotherapy (NAC) within the context of a clinical trial. The NACATRINE trial is a phase II, single-center, randomized, open-label clinical trial that investigated the addition of carboplatin to sequential anthracycline- and taxane-based NAC for TNBC. We evaluated the gene expression in untreated samples to investigate its association with pCR, overall survival (OS), and disease-free survival (DFS). RNA was extracted from the tissue biopsy, and the nCounter Breast Cancer panel was used to analyze gene expression. Of the 66 patients included in the gene expression profiling analysis, 24 (36.4%) achieved pCR and 42 (63.6%) had residual disease. In unsupervised hierarchical clustering analyses, differentially expressed genes between patients with and without pCR were identified irrespective of the treatment (24 genes), carboplatin (37 genes), and non-carboplatin (27 genes) arms. In receiver operating characteristic (ROC) curve analysis, 10 genes in the carboplatin arm (area under the ROC curve [AUC], 0.936) and three genes in the non-carboplatin arm (AUC, 0.939) were considered to be potential pCR-associated biomarkers. We identified genes that were associated with improvements in OS and DFS in addition to being related to pCR. We successfully identified gene expression signatures associated with pCR in pretreatment samples of patients with TNBC treated with NAC. Further investigation of these biomarkers is warranted.
Cortical Auditory Evoked Potential Testing in Children With Auditory Neuropathy Spectrum Disorder
Authors: Morlet Thierry , Valania Jenna , Walter Cassidy , Morini Giovanna , O'Reilly Robert C. , Parkes William , Pritchett Cedric 
Published: December 2023

Purpose:
In the present report, we reviewed the role of cortical auditory evoked potentials (CAEPs) as an objective measure during the evaluation and management process in children with auditory neuropathy spectrum disorder (ANSD).

Method:
We reviewed the results of CAEP recordings in 66 patients with ANSD aged between 2 months and 12 years and assessed the relationship between their characteristics (prevalence, morphology, latencies, and amplitudes) and various clinical features, including the mode of medical management.

Results:

Overall, the CAEPs were present in 85.2% of the ears tested. Factors such as prematurity, medical complexity, neuronal issues, or presence of syndromes did not have an effect on the presence or absence of CAEPs. CAEP latencies were significantly shorter in ears with cochlear nerve deficiency than in ears with a normal caliber nerve. Three different patterns of CAEP responses were observed in patients with bilateral ANSD and present cochlear nerves: (a) responses with normal morphology and presence of both P1-P2
complex
and N2 components, (b) responses with abnormal morphology and presence of the N2 component but undefined P1-P2
complex
peak, and (c) entirely absent responses. None of the patients with normal, mild, or moderate degree of hearing loss had a complete absence of CAEP responses. No significant differences were uncovered when comparing the latencies across unaided and aided children and children who later received cochlear implants.

Conclusions:
The CAEP protocol used in our ANSD program did inform about the presence or absence of central auditory stimulation. Absent responses typically fit into an overall picture of complete auditory deprivation and all of these children were ultimately offered cochlear implants after failing to develop oral language. Present responses, on the other hand, were acknowledged as a sign of some degree of auditory stimulation but always interpreted with caution given that prognostic implications remain unclear.
The disk of the eruptive protostar V900 Mon
Authors: Lykou F. , Ábrahám P. , Cruz-Sáenz de Miera F. , Varga J. , Kóspál Á. , Bouwman J. , Chen L. , Kraus S. , Sitko M. L. , Russell R. W. , Pikhartova M. 
Published: December 2023

Aims. In this work, we study the silicate dust content in the disk of one of the youngest eruptive stars, V900 Mon, at the highest angular resolution, probing down to the inner 10 au of said disk, and study the historical evolution of the system, traced in part by a newly discovered emission clump.
Methods. We performed high angular resolution MIR interferometric observations of V900 Mon with MATISSE/VLTI with a spatial coverage ranging from 38 to 130-m baselines, and compared them to archival MIDI/VLTI data. We also mined and re-analyzed archival optical and infrared photometry of the star to study its long-term evolution since its eruption in the 1990s. We complemented our findings with integral field spectroscopy data from MUSE/VLT.
Results. The MATISSE/VLTI data suggest a radial variation in the silicate feature in the dusty disk, whereby at large spatial scales (≥10 au) the protostellar disk’s emission is dominated by large-sized (≥1μm) silicate grains, while at smaller spatial scales and closer to the star (≤5 au) silicate emission is absent, suggesting self-shielding. We propose that the self-shielding may be the result of small dust grains at the base of the collimated CO outflow previously detected by ALMA. A newly discovered knot in the MUSE/VLT data, located at a projected distance approximately 27 000 au from the star, is co-aligned with the molecular gas outflow at a P.A. of 250°(±5°) consistent with the position angle and inclination of the disk. The knot is seen in emission in Hα [N II], and the [S II] doublet and its kinematic age is about 5150 yr. This ejected material could originate from a previous eruption.
Deep learning forecasts of cosmic acceleration parameters from DECi-hertz Interferometer Gravitational-wave Observatory
Authors: Sun Mengfei , Li Jin , Cao Shuo , Liu Xiaolin 
Published: December 2023

Context. Validating the accelerating expansion of the universe is an important aspect in improving our understanding of the evolution of the universe. By constraining the cosmic acceleration parameter XH, we can discriminate between the cosmological constant plus cold dark matter (ΛCDM) model and the Lemaître–Tolman–Bondi (LTB) model.
Aims. In this paper, we explore the possibility of constraining the cosmic acceleration parameter with the inspiral gravitational waveform of neutron star binaries (NSBs) in the frequency range of 0.1 Hz–10 Hz, which can be detected by the second-generation space-based gravitational wave detector DECIGO.
Methods. We used a convolutional neural network (CNN) and a long short-term memory (LSTM) network combined with a gated recurrent unit (GRU), along with a Fisher information matrix to derive constraints on the cosmic acceleration parameter, XH.
Results. We assumed that our networks estimate the cosmic acceleration parameter without biases (the expected value of the estimation is equal to the true value). Under this assumption, based on the simulated gravitational wave data with a time duration of one month, we conclude that CNN can limit the relative error to 15.71%, while LSTM network combined with GRU can limit the relative error to 14.14%. Additionally, using a Fisher information matrix for gravitational wave data with a five-year observation can limit the relative error to 32.94%.
Conclusions. Under the assumption of an unbiased estimation, the neural networks can offer a high-precision estimation of the cosmic acceleration parameter at different redshifts. Therefore, DECIGO is expected to provide direct measurements of the acceleration of the universe by observing the chirp signals of coalescing binary neutron stars.
La hiérarchisation des priorités d’autogestion à l’adolescence dans le cadre de la polypathologie allergique : une étude qualitative exploratoire
Authors: Brégeon Aurore , Cifuentes Flor , Lombart Bénédicte , Wanin Stéphanie , Gagnayre Rémi , Morsa Maxime 
Published: December 2023

Introduction : La polypathologie entraîne une priorisation accrue des modalités d’autogestion. Si le phénomène est théorisé chez les adultes, l’influence des particularités de l’adolescence dans la hiérarchisation des priorités reste inconnue. Objectifs : Notre recherche, contextualisée aux maladies atopiques, vise à explorer les facteurs influençant la priorisation de comportements favorables à la santé chez les adolescents. Méthode : 15 adolescents ont participé à un entretien individuel semi-directif puis cinq d’entre eux à un focus groupe. L’analyse des résultats a été réalisée à partir d’un construit théorique convoquant le Health Belief Model de Rosenstock & Becker et le modèle du sens commun de Leventhal. Résultats : Les principaux facteurs influençant la priorisation semblent être l’ampleur de la menace perçue et la qualité de l’environnement social. À distance d’une anaphylaxie ou d’un passage en réanimation, l’impact des pathologies dans la vie devient un facteur très influant. Discussion : L’exploration des facteurs de priorisation relevés dans la littérature chez les adultes semble pouvoir s’appliquer aux adolescents, leurs comportements s’en rapprochant. La nature des pathologies allergiques rend probablement davantage compte des différences observées que la période de l’adolescence. Conclusion : Le construit théorique, la puissance des facteurs dans la priorisation et leurs interactions reste à valider.
Die iliakale Endofibrose im Hochleistungssport - eine diagnostische interdisziplinäre Herausforderung
Authors: Regus Susanne , Schoeffl Isabelle , Knetsch Joachim , Schoeffl Volker , Haase Konstantin 
Published: December 2023

Zusammenfassung
Hintergrund Die iliakale Endofibrose (IE) ist eine seltene arterielle Erkrankung bei Ausdauerathleten, insbesondere Radrennfahrern und Triathleten. Die Diagnostik gilt als Herausforderung, die Latenz vom Beginn erster Symptome bis zur Diagnosestellung beträgt oft mehrere Jahre. An diagnostischen Möglichkeiten sind die Bestimmung des Knöchel-Arm-Dopplerindex (ankle brachial index, ABI) nach maximaler Belastung als ein nicht invasives Verfahren sowie die Duplexsonografie, Schichtbildgebung und die invasive Angiografie zu nennen. Ziel dieser Arbeit ist es, diese zeitliche Verzögerung bis zur korrekten Diagnosestellung seit Erstbeschreibung im Jahr 1985 bis zum Jahr 2021 genauer zu analysieren sowie die wichtigsten diagnostischen Mittel für die Praxis herauszuarbeiten.
Methode Durchführung einer Literaturrecherche gemäß den PRISMA-Kriterien in den Datenbanken PubMed, Web of Science und Cochrane, ergänzt durch eine Suche in Google Scholar bis zum 18.10.2021.
Ergebnisse Es wurden 133 Publikationen identifiziert, die sich thematisch mit der IE bei Ausdauersportlern beschäftigten. In 42 Publikationen (40 Fallberichte und 2 klinische Studien) wurde die Diagnose intraoperativ bestätigt, in 32 (32/43; 74,4%) wurden Aussagen über die Dauer vom Auftreten der ersten Symptome bis zur Diagnosestellung gemacht (Mittelwert 45, Median 36 Monate). Diese Latenz war über den gesamten Beobachtungszeitraum von 1985–2021 konstant, ohne Trend zur Verkürzung. In 24 Arbeiten (24/43; 56%) wurde detailliert über Ergebnisse der ABI-Bestimmung sowie der weiterführenden Diagnostik berichtet. In allen Fällen kam es zu einem Abfall des ABI- Wertes auf weniger als 0,66 (in 5 Fallberichten bereits in Ruhe, in 19 nach Belastung), wohingegen die weiterführende Diagnostik mittels Duplexsonografie, DSA, MRA oder CTA in 3 Fällen (3/24; 12,5%) keinen auffälligen Befund ergab und in 14 Fällen (14/24; 58,3%) eine allenfalls geringgradige Stenosierung zeigte.
Schlussfolgerung Ein Abfall des ABI nach Belastung ist die zuverlässigste Methode, um die iliakale Endofibrose zu diagnostizieren. Es empfiehlt sich, diese nicht invasive und einfach durchführbare Untersuchung in die Leistungsdiagnostik gefährdeter hochambitionierter Ausdauerathleten zu integrieren, um im Idealfall durch eine frühzeitige Diagnosestellung irreversible Gefäßwandschäden zu verhindern sowie die vermutete hohe Dunkelziffer an unerkannten Fällen zu reduzieren.
Biochemische Marker des Knochenstoffwechsels im Blickwinkel
knochenrelevanter Erkrankungen
Authors: Dimai Hans Peter , Obermayer-Pietsch Barbara 
Published: December 2023

ZusammenfassungDas knöcherne Skelett unterliegt zeitlebens einem intensiven Umbau,
welcher sich unter anderem laborchemisch durch Messung von im Blut
zirkulierenden Substraten des Knochenanbaus und Knochenabbaus quantifizieren
lässt. Diese Substrate werden in ihrer Gesamtheit häufig unter
dem Begriff „Knochenumbauparameter“ oder „biochemische
Marker des Knochenumsatzes“ zusammengefasst. Sie können direkt
dem Stoffwechsel knochenspezifischer Zellen entstammen, wie etwa die Alkalische
Phosphatase (ALP), das Osteocalcin (OC) oder die Tartrat-resistente saure
Phosphatase (TRAP), oder im Rahmen des Knochenabbaus aus der organischen
Knochenmatrix freigesetzt werden, wie zum Beispiel das C-terminale oder
N-terminale Telopeptid des Typ-1 Kollagens (CTX, NTX). Für eine
erhebliche Anzahl unterschiedlicher Erkrankungen konnte in den vergangenen
Jahren und Jahrzehnten ein Effekt auf den Knochenstoffwechsel, und somit auf die
entsprechenden Knochenumbauparameter, nachgewiesen werden. Hierbei stehen
Erkrankungen, welche eine Beschleunigung des Knochenumsatzes bewirken jenen
gegenüber, welche zu einer Verlangsamung desselben führen. Die
Messung von Knochenumbauparametern im Blut und somit die Information
über das Ausmaß des Knochenumbaus können
unterstützend für therapeutische Maßnahmen herangezogen
werden. Die diagnostische Bedeutung oder der diagnostische Mehrwert der
Knochenumbauparameter bleiben hierbei allerdings auf einige wenige Ausnahmen
beschränkt.
Are women-who-have-sex-with-women an ‘at-risk’ group for cervical cancer? An exploratory study of women in Aotearoa New Zealand
Authors: Ellis Sonja J. 
Published: December 2023

Background International research consistently indicates that women-who-have-sex-with-women (WSW) are less likely to engage in cervical screening than heterosexual women. In the main, studies have explored rates of engagement and highlighted some reasons for non-engagement. This study extends on this work by exploring perceptions among sexual minority women (WSW) for lower rates of engagement among WSW more generally and is the first study on this topic undertaken in Aotearoa New Zealand. Methods A sample of 177 self-identified WSW domiciled in New Zealand completed an online survey about their engagement in cervical screening, reasons for engaging (or not) in cervical screening, and perceptions of why SMW might be less likely to engage in cervical screening. Results Fewer than half of participants had engaged in cervical screening every 3 years as recommended, with women who had only ever had sex with other women being significantly less likely to have engaged in screening. A lack of clear information about risk relative to sexual history, heteronormativity, and the invasive nature of screening were the dominant reasons for lower engagement among WSW. Conclusions A legacy of misinformation, and endemic heteronormativity in public health messaging around cervical screening is a significant barrier to engagement in screening for WSW. To increase engagement in screening among WSW, public health information needs to specifically address the needs of WSW.
Design and experimental realization of multifunctional anisotropic metasurface for efficient polarization manipulation in microwave frequencies
Authors: Qureshi Ubaid Ur Rahman , Hu Bin , Basir Shahid , Ahmad Munzza , Jalal Abdul , Ismail Khan M 
Published: December 2023

Abstract
This paper presents the realization of a multifunction anisotropic metasurface capable of operating as both a half-waveplate and a quarter-waveplate in the C, X, and Ku bands. The numerical and experimental results demonstrate the metasurface is able to convert linear and circular polarizations to their respective cross-polarizations, as well as achieve linear-to-circular and circular-to-linear polarization conversions in the microwave frequency regime. Notably, the metasurface maintains high conversion efficiencies for both half-wave and quarter-wave plate operations, even when subjected to variations in the incidence angle. The underlying physical mechanism is elucidated through the analysis of eigen values, surface current distribution and the retrieval of effective physical parameters. The proposed metasurface is useful for communication and polarization manipulation devices due to its simple construction, compact size, angular stability, and multi-functionality.
Analytical modelling and reliability analysis of charge plasma-assisted Mg2Si/Si heterojunction doping less DGTFET for low-power switching applications
Authors: Goyal Preeti , Srivastava Garima , Madan Jaya , Pandey Rahul , Gupta R S 
Published: December 2023

Abstract
Fabrication of tunnel field effect transistor (TFET) confronts various challenges, one of which is random dopant fluctuation (RDF), which diminishes the benefits associated with low subthreshold swing (SS) and high ION/IOFF ratio. By conducting physics-based 2D analytical modelling, this paper proposes a magnesium silicide/silicon (Mg2Si/Si) heterojunction-based doping less double gate tunnel field effect transistor (HB-DL-DGTFET). This work utilizes the concept of charge plasma to tackle the issues of RDF. The analytical analysis in this study is based upon the determination of the center-channel potential by solving 2D Poisson’s equation, considering appropriate boundary conditions. Here, surface potential, electric field, energy bands, drain current and threshold voltage are extracted mathematically. In addition to the aforementioned parameters, several other analog performance parameters like transconductance, drain conductance, device efficiency, intrinsic gain, output resistance and channel resistance have also been studied in this context. The analytical findings have been duly validated using the ATLAS TCAD device simulator. Furthermore, this work focuses on exploring proposed device reliability through an investigation of, the influence of interface trap charges (ITC), present at the Si/SiO2 interface. The study analyses ITC's impact on analog performance and the obtained results are compared with that of conventional doping less DGTFET (C-DL-DGTFET). The simulation results reveal that HB-DL-DGTFET exhibits greater immunity against ITC. Thus, validating the potential of HB-DL-DGTFET as a superior candidate for low-power switching applications.
Machine learning-based prediction of Q-voter model in complex networks
Authors: Pineda Aruane M , Kent Paul , Connaughton Colm , Rodrigues Francisco A 
Published: December 2023

Abstract
In this article, we consider machine learning algorithms to accurately predict two variables associated with the Q-voter model in complex networks, i.e. (i) the consensus time and (ii) the frequency of opinion changes. Leveraging nine topological measures of the underlying networks, we verify that the clustering coefficient (C) and information centrality emerge as the most important predictors for these outcomes. Notably, the machine learning algorithms demonstrate accuracy across three distinct initialization methods of the Q-voter model, including random selection and the involvement of high- and low-degree agents with positive opinions. By unraveling the intricate interplay between network structure and dynamics, this research sheds light on the underlying mechanisms responsible for polarization effects and other dynamic patterns in social systems. Adopting a holistic approach that comprehends the complexity of network systems, this study offers insights into the intricate dynamics associated with polarization effects and paves the way for investigating the structure and dynamics of complex systems through modern methods of machine learning.
Post-operative outcomes and identification of risk factors for complications after emergency intestinal stoma surgery – a multi-centre retrospective study
Authors: MacDonald Scott , Wong Li-Siang , Ng Hwei Jene , Quasim Tara , Moug Susan 
Published: December 2023

Abstract

Aim
Approximately 4000 patients undergo emergency intestinal stoma surgery annually in the UK. Stoma-related complications (SRCs) are heterogenous but have previously been sub-categorised into ‘early’ or ‘late-SRCs’. Early-SRCs include: skin excoriation; stoma necrosis; and high-output and generally occur within 30 days post-operatively. Late-SRCs include: para-stomal herniae; retraction; and prolapse. There is a paucity of research investigating risk factors for SRCs within the emergency cohort.
This paper aims to describe the incidence of SRCs after emergency intestinal surgery and to identify potential risk factors for SRCs.

Methods
Consecutive patients undergoing emergency intestinal stoma surgery (colostomy, ileostomy or jejunostomy) were identified prospectively from 3 acute hospital sites over 3 years from the ELLSA (Emergency Laparotomy and Laparoscopic Scottish Audit) database. Patients were followed up for a minimum of 1 year. A multi-variate logistic regression model was used to identify risk factors for early and late-SRCs.

Results
n=455 patients were included (Median follow-up-19 months; Age(median) 64 years; Male:Female-0.52;56.7% ileostomies). 54.1% of patients experienced early-SRCs and 51% experienced late-SRCs. n=219 (48.1%) of patients had their stoma sited pre-operatively. Risk factors for early-SRCs included end ileostomy formation (OR 3.51(2.24-5.49), p&lt;0.001), while pre-operative stoma-siting was found to be protective (OR 0.53(0.35-0.83), p=0.005). Patient obesity (OR 3.11(1.92-5.03), p&lt;0.001) and re-operation for elective complications (OR 4.18(2.01-8.69), p&lt;0.001) were risk factors for late-SRCs.

Conclusion
Stoma-related complications after emergency surgery are common. Pre-operative stoma siting is the only truly modifiable risk factor to reduce SRCs, and further research should be aimed at methods of improving this in the emergency setting.