bluuebunny/crossref_metadata_2025_split huggingface dataset:
Combined genicular artery embolization and genicular nerve block to treat chronic pain following total knee arthroplasty
Authors: Zhou Wenhui , Bultman Eric , Mandl Lisa A. , Giori Nicholas J. , Kishore Sirish A. 
Published: January 2024

Abstract
Background
Chronic knee pain after total knee arthroplasty (TKA) is a common complication that is difficult to treat. This report aims to highlight the benefit of combining embolotherapy and neurolysis intervention for symptomatic relief of post-TKA pain in a patient with long-standing pain refractory to conservative management.

Case presentation
A 77-year-old man who had previously undergone left knee arthroplasty has been grappling with worsening knee effusion and debilitating pain, resulting in limited mobility and progressive musculature deconditioning over a 20-year period. Diagnostic arteriography showed marked diffuse periarticular hyperemia around the medial and lateral joint spaces of the left knee, along with capsular distention. The patient initially underwent microsphere embolization to selectively target multiple branches of the genicular arteries, achieving a 50% reduction in pain at the one-month follow-up. Subsequently, the patient underwent image-guided genicular nerve neurolysis, targeting multiple branches of the genicular nerves, which led to further pain reduction (80% compared to the initial presentation or 60% compared to post-embolization) at the one-month follow-up. This improvement facilitated weight-bearing and enabled participation in physical therapy, with sustained pain relief over the 10-month follow-up period.

Conclusion
The combination of genicular artery embolization and genicular nerve block may be a technically safe and effective option for alleviating chronic pain after total knee arthroplasty.
Determining Differences in Perioperative Functional Mobility Patterns in Lumbar Decompression Versus Fusion Patients Using Smartphone Activity Data
Authors: Chauhan Daksh , Ahmad Hasan S. , Hamade Ali , Yang Andrew I. , Wathen Connor , Ghenbot Yohannes , Mannam Sai , Subtirelu Robert , Bashti Malek , Wang Michael Y. , Basil Gregory , Yoon Jang W. 
Published: January 2024

BACKGROUND AND OBJECTIVES:
Smartphone activity data recorded through high-fidelity accelerometry can provide accurate postoperative assessments of patient mobility. The “big data” available through smartphones allows for advanced analyses, yielding insight into patient well-being. This study compared rate of change in functional activity data between lumbar fusion (LF) and lumbar decompression (LD) patients to determine preoperative and postoperative course differences.

METHODS:
Twenty-three LF and 18 LD patients were retrospectively included. Activity data (steps per day) recorded in Apple Health, encompassing over 70 000 perioperative data points, was classified into 6 temporal epochs representing distinct functional states, including acute preoperative decline, immediate postoperative recovery, and postoperative decline. The daily rate of change of each patient's step counts was calculated for each perioperative epoch.

RESULTS:
Patients undergoing LF demonstrated steeper preoperative declines than LD patients based on the first derivative of step count data (P = .045). In the surgical recovery phase, LF patients had slower recoveries (P = .041), and LF patients experienced steeper postoperative secondary declines than LD patients did (P = .010). The rate of change of steps per day demonstrated varying perioperative trajectories that were not explained by differences in age, comorbidities, or levels operated.

CONCLUSION:
Patients undergoing LF and LD have distinct perioperative activity profiles characterized by the rate of change in the patient daily steps. Daily steps and their rate of change is thus a valuable metric in phenotyping patients and understanding their postsurgical outcomes. Prospective studies are needed to expand upon these data and establish causal links between preoperative patient mobility, patient characteristics, and postoperative functional outcomes.
Helping Small Businesses Become More Data-Driven: A Field Experiment on eBay
Authors: Bar-Gill Sagit , Brynjolfsson Erik , Hak Nir 
Published: January 2024

As digitization sweeps across industries and markets, analytics and data-driven decision making (DDD) are becoming increasingly important. The adoption of analytics and DDD has been slower in small-to-medium enterprises (SMEs) compared with large firms, and reliable causal estimates of the impacts of analytics tools for small businesses have been lacking. We derive experiment-based estimates of the impact of an analytics tool on SME outcomes, analyzing the randomized introduction of eBay’s Seller Hub (SH), a data-rich seller dashboard. We find that SH adoption is associated with increased DDD and that access to SH increases e-retailers’ revenues by 3.6% on average, as more items are transacted and service quality increases, without increases in average prices. Our results suggest that analytics and DDD help SMEs establish a competitive advantage. Managerial practices play an important role in reaping the benefits from the analytics dashboard, as more than a third of the SH impact is driven by active performance monitoring. Digital platforms should therefore embed analytics tools to support SMEs to increase entry and revenues. Furthermore, policies to support small businesses’ transition to the data era should address analytics and DDD gaps by ensuring access to both tools like SH and to appropriate managerial training. This paper was accepted by Anindya Ghose, information systems. Funding: This work was supported by the United States-Israel Binational Science Foundation [Grant 2018263]. Supplemental Material: The data files are available at https://doi.org/10.1287/mnsc.2021.02026 .
Recovering Dantzig–Wolfe Bounds by Cutting Planes
Authors: Chen Rui , Günlük Oktay , Lodi Andrea 
Published: January 2024

Leveraging Dantzig–Wolfe Decomposition in the Original Variable Space for Mixed-Integer Programming Dantzig–Wolfe decomposition has been extensively applied to solve large-scale mixed-integer programs with decomposable structures, leading to exact solution approaches, such as branch and price. However, these approaches would require solving the problem in an extended variable space and are not readily present in off-the-shelf solvers. In “Recovering Dantzig–Wolfe Bounds by Cutting Planes,” Chen, Günlük, and Lodi propose a computational effective approach for generating cutting planes from Dantzig–Wolfe decomposition to enhance branch and cut in the space of original variables. The proposed approach requires a relatively small number of cutting planes to recover the strength of the Dantzig–Wolfe dual bound and should be easy to implement in general-purpose mixed-integer programming solvers. The authors show that these cutting planes typically lead to a formulation with lower dual degeneracy and hence, a better computational performance than naïve approaches, such as the objective function cut.
The impact of falls on activities of daily living in older adults: A retrospective cohort analysis
Authors: Adam Claire E. , Fitzpatrick Annette L. , Leary Cindy S. , Ilango Sindana D. , Phelan Elizabeth A. , Semmens Erin O. 
Published: January 2024

Background
Falls contribute to impairments in activities of daily living (ADLs), resulting in significant declines in the quality of life, safety, and functioning of older adults. Understanding the magnitude and duration of the effect of falls on ADLs, as well as identifying the characteristics of older adults more likely to have post-fall ADL impairment is critical to inform fall prevention and post-fall intervention. The purpose of this study is to 1) Quantify the association between falls and post-fall ADL impairment and 2) Model trajectories of ADL impairment pre- and post-fall to estimate the long-term impact of falls and identify characteristics of older adults most likely to have impairment.

Method
Study participants were from the Ginkgo Evaluation of Memory Study, a randomized controlled trial in older adults (age 75+) in the United States. Self-reported incident falls and ADL scores were ascertained every 6 months over a 7-year study period. We used Cox proportional hazards analyses (n = 2091) to quantify the association between falls and ADL impairment and latent class trajectory modeling (n = 748) to visualize trajectories of ADL impairment pre-and post-fall.

Results
Falls reported in the previous 6 months were associated with impairment in ADLs (HR: 1.42; 95% CI 1.32, 1.52) in fully adjusted models. Based on trajectory modeling (n = 748), 19% (n = 139) of participants had increased, persistent ADL impairment after falling. Participants who were female, lived in a neighborhood with higher deprivation, or experienced polypharmacy were more likely to have ADL impairment post-fall.

Conclusions
Falls are associated with increased ADL impairment, and this impairment can persist over time. It is crucial that all older adults, and particularly those at higher risk of post-fall ADL impairment have access to comprehensive fall risk assessment and evidence-based fall prevention interventions, to help mitigate the negative impacts on ADL function.
From Granada to Berlin: The Alhambra Cupola, Anna McSweeney (2020)
Authors: Slingluff Sarah 
Published: January 2024

Review of: From Granada to Berlin: The Alhambra Cupola, Anna McSweeney (2020)
Dortmund: Verlag Kettler, 193 pp., 77 colour illus.,
ISBN: 978-3-86206-831-9, £22.75 (paperback)
IL Mare Della Nostra Storia (The Sea of Our History), Giovanna Gagliardo (Dir.) (2018)
Authors: Laviosa Flavia 
Published: January 2024

Review of: IL Mare Della Nostra Storia (The Sea of Our History), Giovanna Gagliardo (Dir.) (2018)
Italy: Istituto Luce Cinecittà (b/w, 94’)
What Drives the Impact of Corporate Governance on Firm Value? Evidence from Earnings Management at Indonesian Sharia Stock Index (ISSI)
Authors: Erdin Maulana Tristianto  , Ridha M. Arsyadi 
Published: January 2024

Purpose: This study sought empirical evidence on the impact of corporate governance as proxied by the board of commissioner's size, managerial ownership, and audit quality on firm value using earnings management as an intervening variable in energy sector companies indexed by the ISSI and listed on the Indonesia Stock Exchange from 2014 to 2022.
Methodology: This study uses purposive sampling technique and panel data, resulting in 171 selected sample data units that will be processed using eviews.
Findings: Managerial ownership, audit quality, and earnings management all have a significant and beneficial impact on firm value. However, the board of commissioners has a negative impact. Aside from that, the board of commissioners's size and managerial ownership do not affect earnings management, but audit quality has a negative effect. Earnings management as an intervening variable influences corporate governance variables.

Novelty: This research attempts to provide a novel viewpoint on how political instability in a country can affect the investment climate in the Indonesian energy sector, which has received little attention previously. This study also acknowledges the inconsistency of previous research findings regarding the relationship between corporate governance and firm value, paving the way for incorporating earnings management variables as mediators and ultimately contributing to our understanding of the complex dynamics between these elements.
Extracellular vesicles from obese and diabetic mouse plasma alter C2C12 myotube glucose uptake and gene expression
Authors: Pitzer Christopher R. , Paez Hector G. , Ferrandi Peter J. , Mohamed Junaith S. , Alway Stephen E. 
Published: January 2024

AbstractRecent studies have indicated a role for circulating extracellular vesicles (EVs) in the pathogenesis of multiple diseases. However, most in vitro studies have used variable and arbitrary doses of EVs rather than interpreting EVs as an existing component of standard skeletal muscle cell culture media. The current study provides an initial investigation into the effects of circulating EVs on the metabolic phenotype of C2C12 myotubes by replacing EVs from fetal bovine serum with circulating EVs from control mice or mice with obesity and type 2 diabetes (OT2D). We report that EVs associated with OT2D decrease 2‐NBDG uptake (a proxy measure of glucose uptake) in the insulin‐stimulated state compared to controls. OT2D associated EV treatment also significantly decreased myosin heavy chain type 1 (MHCI) mRNA abundance in myotubes but had no effect on mRNA expression of any other myosin heavy chain isoforms. OT2D‐associated circulating EVs also significantly increased lipid accumulation within myotubes without altering the expression of a selection of genes important for lipid entry, synthesis, or catabolism. The data indicate that, in a severely diabetic state, circulating EVs may contribute to insulin resistance and alter gene expression in myotubes in a manner consistent with the skeletal muscle phenotype observed in OT2D.
The Development of Learning Media for Mobile Learning on Virus Contents
Authors: Jannah Unsya Oktami , Sukaesih Sri , Abdullah Muhammad 
Published: January 2024

Learning media is a vehicle for distributing messages and learning information which, if designed properly, will greatly help students achieve learning goals. The results of first observations made on students of SMA N 1 Boja, data obtained that only 50% of students remember virus content during X class, and there are more than 90% of students who have and bring Android smartphones to school which should be used for learning. While the results of interviews with biology teachers at SMA N 1 Boja class X, the difficulties in teaching virus content are the absence of teaching aids, content that tends to be abstract and students who tend to memorize rather than understand. Viruses are a content that is difficult to observe because of its form that cannot be seen with the naked eye because of its very small size. Mobile learning media is an innovation of learning media based on Android and information technology (IT) that can be used without the need for an internet connection and can be used anytime and anywhere to learn. Starting from the problem of abstract virus content and its small size so it cannot be seen with the naked eye, and the media used by the teacher is only power point, as well as the potential of students who already have and bring Android smartphones to school but have not been used optimally in learning, it is necessary to develop an android-based learning media, namely mobile learning.
Sampling using random sampling technique. In this study using the Pre Experimental Design method with One-Group Pretest-Posttest Design with a sample of class X MIA students at SMA N 1 Boja. The instruments used are: interviews, questionnaires and documentation.
Validation was carried out by a biology lecturer at Unnes and a biology teacher at SMA N 1 Boja with a score of >81% (very valid). A small-scale trial was conducted in class XI MIPA 1 with results >91% (effective), while the student and teacher questionnaire responses reached a score of >81%. A large-scale trial was carried out for class X MIPA 4 by conducting a pretest and posttest with classical completeness results >75% (effective). Thus the learning media for mobile learning virus content developed is feasible and effective to be used as a learning resource.
The Ability of Biology Education Students in Arrange 2019 Revised Lesson Plan
Authors: Janah Nurul , WH Nugrahaningsih 
Published: January 2024

Lesson plans serve as guidelines for teachers when managing classes. However, some teachers choose to use the previous school year's lesson plans or copy their colleagues' lesson plans, this is due to the very detailed preparation of the 2013 curriculum lesson plans. This is the background for the Minister of Education and Culture to issue Letter Number 14 of 2019 concerning Simplification of lesson plan into three main components, namely learning objectives, learning activities, and assessment.. The purpose of this study was to analyze the ability of Biology Education Students in arrange the 2019 Revised lesson plan. The research method used was descriptive quantitative with survey techniques. The research sample was 50 UNNES Biology Education Students. Instruments in the form of lesson plan assessment sheets and student response questionnaires. The results obtained are the ability of Biology Students in general is included in the very good category by 14%, in the good category by 10%, in the average category by 44%, in the low category by 28%, and in the very low by 4%. Biology Education Students are mostly in the average category of 22 students. The total of students in the very good, good, and average categories is 34 students with a minimum score of 79,2. Most of the Biology Education Students in preparing the 2019 Revised lesson plan (34 students) have been able to compose the lesson plan components, especially the lesson plan identity components, learning objectives, selection of learning media, learning steps, assessment, and good language in preparing lesson plan. Although there are some students who have general deficiencies in the time allocation component that is not included in the learning scenario, learning resources that only use textbooks, lesson plans do not bring students closer to interacting with the environment, evaluations do not include remedial and enrichment programs, and assessment attachments are sometimes missed. The results of the student response questionnaires became crosscheck to determine the level of student knowledge .The result of learning objective percentage of 91.2%, an assessment of 90.8%, an evaluation of 89.2%, preparation and guidelines lesson plan 87.6%, learning steps 86.4%, basic knowledge about the differences between the 2013 Curriculum lesson plan and the 2019 Revised lesson plan 85.36%, knowledge about the advantages and disadvantages of lesson plan 84.13%. The concluision is most (34 students) Biology Education Students have been able to prepare the 2019 Revised lesson plan highest achievement is 99 and the lowest achievement is 68. The results of the student response questionnaire generally show that Biology Education students are good at understanding the arrange of the 2019 lesson plan.
The Development of Learning Videos Using Wondershare Filmora Software on Human Reproductive System Material
Authors: Wardana Irfan Ihza , Utami Nur Rahayu 
Published: January 2024

The Covid-19 pandemic has changed the way people live, including in the field of education. One of them is WFH (work from home), which causes the learning process to be carried out from home by online. Students found it difficult to understand the material during online learning which caused learning outcomes to decrease. On the other hand, the development of technology and information can be used so that it is beneficial for education. The advantages of learning video media greatly assist the teacher in conveying the material to be delivered and students better understand the material presented by the teacher. For this reason, it was necessary to develop video-based media for learning the Reproductive System material. The purpose of this study was to analyze the validity, feasibility, and influence of media effectiveness on student learning outcomes based on learning videos on the Reproductive System material. The research steps that were passed used the 4D development model, namely Define, Design, Development, and Disseminate. The research instruments used were student questionnaire sheets, interview sheets, validity sheets, teacher and student response questionnaire sheets, as well as pre-test/post-test sheets. The results of research on the Reproductive System learning video media have met the criteria of being very valid by media experts at 98% and valid by material experts with a score of 72%, the media feasibility score is 94% or very feasible by a questionnaire of teachers and students, and learning video media is effective in improving results student learning on the subject of the Human Reproductive System at SMA Negeri 1 Banjarnegara.
Apie religines mažumas, visuomenę ir valstybę šiuolaikinėje Lietuvoje
Authors: Diržys Adas 
Published: January 2024

Knygos recenzija: Ališauskienė, Milda. 2023. Religinės mažumos, visuomenė ir valstybė šiuolaikinėje Lietuvoje. Kaunas: Vytauto Didžiojo universitetas. p. 213. ISBN 978-609-467-556-0
EFFECT OF ETHANOL-WATER CONCENTRATION AS EXTRACTION SOLVENT ON ANTIOXIDANT ACTIVITY OF Acalypha indica
Authors: Fadhila Salma Iza , Hayati Elok Kamilah , Rafi Mohamad , Sabarudin Akhmad 
Published: January 2024

Acalypha indica is an abundant and obtainable wild weed plant in Indonesia. This is a possible opportunity to enhance its utility. The effect of free radicals is one of the factors that contribute to oxidative stress in the body, which can lead to cell damage and trigger various diseases. Plants rich in antioxidants can inhibit free radical reactions and protect the body from oxidative stress. In this study, we conducted the identification of major metabolite compounds using UHPLC-Q-Orbitrap HRMS from 70% ethanol extracts of Acalypha indica. We also performed phytochemical and antioxidant activity tests with various concentrations of ethanol-water solvents including water, 30%, 50%, 70% ethanol, and absolute ethanol to determine the optimal extraction conditions and the influence of solvent concentration on the antioxidant activity of Acalypha indica extract. The results of UHPLC-Q-Orbitrap HRMS identification showed that the 70% ethanol extract of Acalypha indica contains 10 major compounds suspected to correlate with its antioxidant activity. These include five flavonoids compounds (palasitrin, vitexin 2"-o-p-coumarate, isorhamnetin 3- (3",6"-di-p-coumarylglucoside), peucenin, and sulfuretin), two amino acid compounds (2-amino-3-carboxymuconic acid semialdehyde and N-Acetyl-L-phenylalanine), two carboxylic acid compound (citric acid and traumatic acid), and one phenolic compound (quinic acid). Phytochemical tests show positive results for flavonoids, tannins, alkaloids, and triterpenoids in each of water, 30%, 50%, 70% ethanol, and absolute ethanol extracts. The best antioxidant activity was obtained from the 70% ethanol extract with an IC50 value of 47.064 ppm, categorizing it as an extremely strong antioxidant.