bluuebunny/crossref_metadata_2025_split huggingface dataset:
Competencias Comunicativas a Través de Cuentos Infantiles en Estudiantes Wayuu del Quinto Grado en la I.E.I N. º 9 Maicao la Guajira
Authors: Rincón Jayariyu Hortensio Eduardo 
Published: January 2024

El presente proyecto investigativo tiene como objetivo general comprender las competencias comunicativas, a través de cuentos infantiles en estudiantes wayuu del quinto grado en la I.E.I N 9 de Maicao la Guajira. Esta investigación involucra las competencias comunicativas y la lectura de cuentos infantiles desde un contexto lúdico, didáctico y pedagógico, para potenciar el desarrollo cognitivo de los estudiantes wayuu que habitan esta zona de la geografía colombiana, la investigación fue orientada bajo un paradigma cualitativo, con un diseño de campo y enfoque descriptivo etnográfico, la población seleccionada tuvo conformada por siete (7) estudiantes entre niños y niñas, por ser los que mostraban un poco más de habilidades para leer, hablar y escribir en castellano, los demás, al no tener un dominio básico de este idioma, solo se les requirió para adquirir información por medio técnicas como la entrevista, lecturas de cuantos infantiles, charlas educativas, la observación, para recoger la información se implementaron instrumentos como formulario de preguntas, el taller, diario de campo, la valides de tales instrumentos fue realizada por expertos. En esta investigación se concluye, que la incidencia de las competencias comunicativa, son de suma importancia para el desarrollo intelectual y cognitivo de los estudiantes, y el docente debe transformar sus prácticas educativas, así como su sistema de enseñanza – aprendizaje por un modelo intercultural bilingüe, que logre despertar el interés por aprender de los educandos.De acuerdo con Arnao; M. Aguilar; F. y Santisteban; K. (2013) utilizar las competencias comunicativas significa que los educandos manejen el lenguaje con eficacia, eficiencia y efectividad en los diferentes aspectos de su vida, y sobre todo en el contexto escolar (p.104) en ese orden de ideas, apropiarse de estas competencias les permitirá a los educandos potenciar sus conocimientos académicos y fortalecer sus competencias intelectuales, porque al leer fluidamente y tener un rango aceptable de comprensión, le permite incorporar nueva información a su sistema cognitivo.
Profilaxia de úlcera por estresse em pacientes internados em unidades de terapia intensiva
Authors: Cazumbá Larissa Gomes 
Published: January 2024

Objetivo: Avaliar a profilaxia de úlcera por estresse em pacientes internados em unidades de terapia intensiva (UTIs) de um hospital geral da Bahia. Métodos: Trata-se de um estudo de corte transversal descritivo, sendo a amostra constituida por prontuários de pacientes internados em Unidades de Terapia Intensiva de um hospital geral da Bahia, no período de julho a dezembro de 2022. Foram obtidos dados sobre o perfil clínico dos pacientes, como diagnóstico médico e indicação para profilaxia de úlcera por estresse, além de dados sociodemográficos. Resultados: Foram analisados 111 prontuários médicos. O principal motivo encontrado para o uso da profilaxia de UE foi a ventilação mecânica por mais de 48 horas, constituindo 23,42% dos casos. 59,45% dos pacientes apresentaram alto risco para o desenvolvimento de úlcera por estresse, sendo que a prevalência de prescrição para profilaxia de úlcera por estresse nas UTIs avaliadas foi de 58,55%. Observou-se a presença do uso indevido da profilaxia em apenas 2,7% dos casos. Em relação aos medicamentos mais utilizados, observou-se a predominância do pantoprazol (52,25%). Conclusões: A profilaxia para úlcera por estresse é largamente utilizada nas Unidades de Terapia Intensiva da instituição analisada e, embora não tenha sido constatado uso irracional da profilaxia de úlcera por estresse, é evidente a importância de estabelecer um protocolo clínico que forneça orientações apropriadas para a prescrição dos medicamentos profiláticos.
Palavra-chaves: Profilaxia.Úlcera péptica.Mucosa Gástrica.
L’ombre au tableau : ce que l’art britannique (ne) dit (pas) de la souffrance animale
Authors: Tholoniat Yann 
Published: January 2024

L’art britannique est réputé pour ses peintres animaliers depuis le XVIIIe siècle. La peinture animale a évolué selon les demandes, en passant notamment de représentations de chasses à courre et de courses d’animaux d’abord, dont George Stubbs est le principal exemple, à des portraits animaliers ensuite, à l’époque victorienne, avec Edwin Landseer. S’ajoute à cela la tendance de l’esprit des Lumières à explorer les ressorts de la nature – et d’utiliser les animaux dans ce but : le tableau de Wright, An Experiment on a Bird in the Air-Pump (1768), illustre cet aspect. Les animaux sont réduits au silence par les humains : ces derniers rechignent en effet à considérer que les animaux communiquent et expriment des émotions personnelles. De plus, la peinture occidentale est un art dans lequel la parole, ou la communication, passe essentiellement par la mise en scène dramatique et la symbolisation. Au xixe siècle, les peintres préraphaélites utilisent les animaux dans une perspective allégorique, comme le montre bien The Scapegoat de William Holman Hunt. À la fin du xxe siècle, Damien Hirst essaya d’apaiser les polémiques suscitées par ses morceaux d’animaux conservés dans du formol en attirant l’attention sur le massacre des vaches à l’époque de la pandémie due à la maladie de Creuzfeldt-Jakob. En étudiant l’évolution des pratiques artistiques en Grande-Bretagne, nous nous interrogerons sur ce déni dans l’art britannique, qui, paradoxalement, était la souffrance animale dans le geste même de représenter des animaux non humains.
Reconstruire le point de vue animal. Retour sur un atelier de réécriture à l’université
Authors: Bessonnet Jodie Lou 
Published: January 2024

Cet article présente la mise en œuvre à l’université d’un atelier d’écriture sur le point de vue animal afin d’appréhender la place et la forme que peuvent prendre les études animales dans les cursus universitaires, ainsi que la richesse des apprentissages pluridisciplinaires qu’elles offrent. L’atelier s’est appuyé d’une part sur les Biographies animales de l’historien Éric Baratay (2017), d’autre part sur les œuvres littéraires qui l’ont inspiré et que la classe devait réécrire. Le contenu théorique apporté couvrait des notions de narratologie, d’analyse littéraire, et proposait une approche pluridisciplinaire du concept d’anthropomorphisme. L’analyse des réécritures auxquelles a abouti le cours met en lumière des tendances propres à l’écriture d’un point de vue animal et souligne la difficulté pour les écrivant·es de se libérer des biais anthropomorphiques et anthropocentriques. Les retours étudiants positifs encouragent à proposer davantage ce type d’exercice.
Efficacy against Lung Cancer Is Augmented by Combining Aberrantly N-Glycosylated T Cells with a Chimeric Antigen Receptor Targeting Fragile X Mental Retardation 1 Neighbor
Authors: Toyofuku Toshihiko , Ishikawa Takako , Nojima Satoshi , Kumanogoh Atsushi 
Published: January 2024

Abstract
The adaptive transfer of T cells redirected to cancer cells via chimeric Ag receptors (CARs) has produced clinical benefits for the treatment of hematologic diseases. To extend this approach to solid cancer, we screened CARs targeting surface Ags on human lung cancer cells using (to our knowledge) novel expression cloning based on the Ag receptor-induced transcriptional activation of IL-2. Isolated CARs were directed against fragile X mental retardation 1 neighbor (FMR1NB), a cancer-testis Ag that is expressed by malignant cells and adult testicular germ cells. Anti-FMR1NB CAR human T cells demonstrated target-specific cytotoxicity and successfully controlled tumor growth in mouse xenograft models of lung cancer. Furthermore, to protect CAR T cells from immune-inhibitory molecules, which are present in the tumor microenvironment, we introduced anti-FMR1NB CARs into 2-deoxy-glucose (2DG)–treated human T cells. These cells exhibited reduced binding affinity to immune-inhibitory molecules, and the suppressive effects of these molecules were resisted through blockade of the N-glycosylation of their receptors. Anti-FMR1NB CARs in 2DG-treated human T cells augmented target-specific cytotoxicity in vitro and in vivo. Thus, our findings demonstrated the feasibility of eradicating lung cancer cells using 2DG-treated human T cells, which are able to direct tumor-specific FMR1NB via CARs and survive in the suppressive tumor microenvironment.
Role of Artificial Intelligence in case of Micro Enterprises and Tribal Entrepreneurships for Sustainable Economic Development
Authors: Sahoo Deepali Rani , Teena  
Published: January 2024

INTRODUCTION: Tribal entrepreneurship can be understood as infusing the knowledge of commerce and trade into the tribal groups and thereby exploring their products and known for their economic betterment and social advancement. An accumulating body of research has demonstrated that artificial intelligence (AI) is an indistinguishable feature of the fourth industrial revolution. This study integrates the literature on AI and new technologies to examine the constraining and facilitating forces for developing and scaling-up AI-enabling technologies in Africa. This article proposes an integrated conceptual model to elucidate the range of external drivers encompassing global competitive drivers, and market and industry drivers. The internal drivers include the potential to enhance product development speed, improve quality, drive production cost down, and minimise errors and manual processes in organisations.
OBJECTIVES: In this study, socio-economic status of tribal population has been taken as a reference in order to see whether there is any impact of economic wellbeing on their livelihood [1]. The study is an endeavour to examine the role of micro enterprises for social and economic empowerment of tribal community in Odisha and Andhra Pradesh and role of AI.
RESULTS: The main results obtained in this paper are the following SEM identified that there is a lower degree of positive impact of “Tribal entrepreneurship” on “Economic Empowerment” and “women Empowerment” and lower degree of negative impact on “Social Empowerment”. It is also concluded that Economic Empowerment of tribal entrepreneurs through micro-enterprises has reduced the dependency on private money lenders the most. Women Empowerment of tribal entrepreneurs has helped the women to achieve gender equality and the social Empowerment aids in the development of competency and technical skills through micro-enterprises.
CONCLUSION: The tribal communities in Odisha are regarded as the most disadvantageous group of people in terms of their socio-economic status. The present research makes some pivotal contributions to the current AI literature. First, in spite of the growing recognition that development of new industries and new-business development is increasingly predicated on the adoption of new technologies (Krasniqi and Hajrizi Citation2016), there is a paucity of studies examining contemporary challenges faced by developing nations and their inability to capitalise on such ample and obvious opportunities.
Faltings’ mainp-adic comparison theorems for non-smooth schemes
Authors: He Tongmu 
Published: January 2024

AbstractTo understand thep-adic étale cohomology of a proper smooth variety over ap-adic field, Faltings compared it to the cohomology of his ringed topos, by the so-called Faltings’ mainp-adic comparison theorem, and then deduced various comparisons withp-adic cohomologies originating from differential forms. In this article, we generalize the former to any proper and finitely presented morphism of coherent schemes over an absolute integral closure of$\mathbb {Z}_p$(without any smoothness assumption) for torsion abelian étale sheaves (not necessarily finite locally constant). Our proof relies on our cohomological descent for Faltings’ ringed topos, using a variant of de Jong’s alteration theorem for morphisms of schemes due to Gabber–Illusie–Temkin to reduce to the relative case of proper log-smooth morphisms of log-smooth schemes over a complete discrete valuation ring proved by Abbes–Gros. A by-product of our cohomological descent is a new construction of Faltings’ comparison morphism, which does not use Achinger’s results on$K(\pi ,1)$-schemes.
Clinical study of different prediction models in predicting diabetic nephropathy in patients with type 2 diabetes mellitus
Authors: Cai Sha-Sha , Zheng Teng-Ye , Wang Kang-Yao , Zhu Hui-Ping 
Published: January 2024

BACKGROUND
Among older adults, type 2 diabetes mellitus (T2DM) is widely recognized as one of the most prevalent diseases. Diabetic nephropathy (DN) is a frequent complication of DM, mainly characterized by renal microvascular damage. Early detection, aggressive prevention, and cure of DN are key to improving prognosis. Establishing a diagnostic and predictive model for DN is crucial in auxiliary diagnosis.
AIM
To investigate the factors that impact T2DM complicated with DN and utilize this information to develop a predictive model.
METHODS
The clinical data of 210 patients diagnosed with T2DM and admitted to the First People’s Hospital of Wenling between August 2019 and August 2022 were retrospectively analyzed. According to whether the patients had DN, they were divided into the DN group (complicated with DN) and the non-DN group (without DN). Multivariate logistic regression analysis was used to explore factors affecting DN in patients with T2DM. The data were randomly split into a training set (n = 147) and a test set (n = 63) in a 7:3 ratio using a random function. The training set was used to construct the nomogram, decision tree, and random forest models, and the test set was used to evaluate the prediction performance of the model by comparing the sensitivity, specificity, accuracy, recall, precision, and area under the receiver operating characteristic curve.
RESULTS
Among the 210 patients with T2DM, 74 (35.34%) had DN. The validation dataset showed that the accuracies of the nomogram, decision tree, and random forest models in predicting DN in patients with T2DM were 0.746, 0.714, and 0.730, respectively. The sensitivities were 0.710, 0.710, and 0.806, respectively; the specificities were 0.844, 0.875, and 0.844, respectively; the area under the receiver operating characteristic curve (AUC) of the patients were 0.811, 0.735, and 0.850, respectively. The Delong test results revealed that the AUC values of the decision tree model were lower than those of the random forest and nomogram models (P < 0.05), whereas the difference in AUC values of the random forest and column-line graph models was not statistically significant (P > 0.05).
CONCLUSION
Among the three prediction models, random forest performs best and can help identify patients with T2DM at high risk of DN.
Heterogeneously elevated branched-chain/aromatic amino acids among new-onset type-2 diabetes mellitus patients are potentially skewed diabetes predictors
Authors: Wang Min , Ou Yang , Yuan Xiang-Lian , Zhu Xiu-Fang , Niu Ben , Kang Zhuang , Zhang Bing , Ahmed Anwar , Xing Guo-Qiang , Su Heng 
Published: January 2024

BACKGROUND
The lack of specific predictors for type-2 diabetes mellitus (T2DM) severely impacts early intervention/prevention efforts. Elevated branched-chain amino acids (BCAAs: Isoleucine, leucine, valine) and aromatic amino acids (AAAs: Tyrosine, tryptophan, phenylalanine)) show high sensitivity and specificity in predicting diabetes in animals and predict T2DM 10-19 years before T2DM onset in clinical studies. However, improvement is needed to support its clinical utility.
AIM
To evaluate the effects of body mass index (BMI) and sex on BCAAs/AAAs in new-onset T2DM individuals with varying body weight.
METHODS
Ninety-seven new-onset T2DM patients (< 12 mo) differing in BMI [normal weight (NW), n = 33, BMI = 22.23 ± 1.60; overweight, n = 42, BMI = 25.9 ± 1.07; obesity (OB), n = 22, BMI = 31.23 ± 2.31] from the First People’s Hospital of Yunnan Province, Kunming, China, were studied. One-way and 2-way ANOVAs were conducted to determine the effects of BMI and sex on BCAAs/AAAs.
RESULTS
Fasting serum AAAs, BCAAs, glutamate, and alanine were greater and high-density lipoprotein (HDL) was lower (P < 0.05, each) in OB-T2DM patients than in NW-T2DM patients, especially in male OB-T2DM patients. Arginine, histidine, leucine, methionine, and lysine were greater in male patients than in female patients. Moreover, histidine, alanine, glutamate, lysine, valine, methionine, leucine, isoleucine, tyrosine, phenylalanine, and tryptophan were significantly correlated with abdominal adiposity, body weight and BMI, whereas isoleucine, leucine and phenylalanine were negatively correlated with HDL.
CONCLUSION
Heterogeneously elevated amino acids, especially BCAAs/AAAs, across new-onset T2DM patients in differing BMI categories revealed a potentially skewed prediction of T2DM development. The higher BCAA/AAA levels in obese T2DM patients would support T2DM prediction in obese individuals, whereas the lower levels of BCAAs/AAAs in NW-T2DM individuals may underestimate T2DM risk in NW individuals. This potentially skewed T2DM prediction should be considered when BCAAs/AAAs are to be used as the T2DM predictor.
Body composition and metabolic syndrome in patients with type 1 diabetes
Authors: Zeng Qiong , Chen Xiao-Jing , He Yi-Ting , Ma Ze-Ming , Wu Yi-Xi , Lin Kun 
Published: January 2024

BACKGROUND
In recent years, the prevalence of obesity and metabolic syndrome in type 1 diabetes (T1DM) patients has gradually increased. Insulin resistance in T1DM deserves attention. It is necessary to clarify the relationship between body composition, metabolic syndrome and insulin resistance in T1DM to guide clinical treatment and intervention.
AIM
To assess body composition (BC) in T1DM patients and evaluate the relationship between BC, metabolic syndrome (MS), and insulin resistance in these indi-viduals.
METHODS
A total of 101 subjects with T1DM, aged 10 years or older, and with a disease duration of over 1 year were included. Bioelectrical impedance analysis using the Tsinghua-Tongfang BC Analyzer BCA-1B was employed to measure various BC parameters. Clinical and laboratory data were collected, and insulin resistance was calculated using the estimated glucose disposal rate (eGDR).
RESULTS
MS was diagnosed in 16/101 patients (15.84%), overweight in 16/101 patients (15.84%), obesity in 4/101 (3.96%), hypertension in 34/101 (33.66%%) and dyslipidemia in 16/101 patients (15.84%). Visceral fat index (VFI) and trunk fat mass were significantly and negatively correlated with eGDR (both P < 0.001). Female patients exhibited higher body fat percentage and visceral fat ratio compared to male patients. Binary logistic regression analysis revealed that significant factors for MS included eGDR [P = 0.017, odds ratio (OR) = 0.109], VFI (P = 0.030, OR = 3.529), and a family history of diabetes (P = 0.004, OR = 0.228). Significant factors for hypertension included eGDR (P < 0.001, OR = 0.488) and skeletal muscle mass (P = 0.003, OR = 1.111). Significant factors for dyslipidemia included trunk fat mass (P = 0.033, OR = 1.202) and eGDR (P = 0.037, OR = 0.708).
CONCLUSION
Visceral fat was found to be a superior predictor of MS compared to conventional measures such as body mass index and waist-to-hip ratio in Chinese individuals with T1DM. BC analysis, specifically identifying visceral fat (trunk fat), may play an important role in identifying the increased risk of MS in non-obese patients with T1DM.
A call to strengthen medication therapy management training in the Kenyan pharmacy undergraduate curriculum: Feedback from a snapshot of the knowledge and practices among pharmacists in diverse disciplines
Authors: Masero Michael Obiero , Wafula Allan Tulienge , Kihugi Veronica Njambi , Mayoka Godfrey Wabwile 
Published: January 2024

Background: The role of the pharmacist has continued to evolve, placing the profession at the fulcrum of holistic patient care, including offering medication therapy management (MTM), a critical component of any effective pharmaceutical care plan.
Objective: This study was conducted to assess the knowledge, attitudes, and practices of Kenyan pharmacists regarding MTM.
Methods: A cross-sectional study was performed whereby Google Form questionnaires were distributed among pharmacists working at hospitals and community pharmacies between 1st October 2022 and 30th November 2022.
Results: Slightly over half (62, 52.5%) of the pharmacists rated themselves as knowledgeable about MTM, with most participants (55, 46.6%) stating that the undergraduate pharmacy curriculum was insufficient to prepare one to offer MTM services competently. Notably, online courses and workshops were the most popular channels (72%) for accessing MTM-related continuous professional development among the respondents.
Conclusion: This study revealed some gaps in the knowledge and competence of undergraduate-level Kenyan pharmacists in their quest to offer MTM services. Therefore, embedding MTM in the undergraduate curriculum can bridge this gap and empower Kenyan pharmacists to provide holistic pharmaceutical care.
“Beli Sekarang Bayar Nanti: Mahasiswi, Spay Later, dan Pandemi Covid-19
Authors: Ilahi Nurwahyu 
Published: January 2024

At the time of the rise of Covid-19 in Indonesia, people had limitations in their activities, including shopping. With various policies issued by the government to limit the space for people to move in order to prevent the spread of the virus, this has made people, including female students, more stimulated to shop online. One of the e-commerce that was popular even before the Covid-19 pandemic was Shopee. Moreover, Shopee provided Shopee Pay Later (Spay Later) feature. While numbers of existing literatures deal with purchasing decision using quantitative approach and consumer legal protection, this article is focused on how female students interested in using Spay Later and how this impacted on their life.
This research was conducted between September 2021 and March 2022 through social media regarding the Shopee application, using a qualitative approach. There are 15 female students who participated in this research and who use Spay Later. Data was collected using in-depth interview and observation.
The study indicates that online shopping through Spay Later has increasingly stimulated because Shopee has a Spay Later feature that makes shopping easier during pandemi Covid-19. One of the Spay Later users who use this application a lot is female college students. They use Spay Later because of the convenience of shopping provided by Shopee, both in terms of shopping and payment methods. Discounted prices and postage are another reason why Spay Later is a shopping choice for female students. So even though they have no intention to shop, these offers stimulated them to shop. Shopping by using Spay Later is also an option because of the availability of various goods, anything is sold at Shopee, so shopping is like a “one stop shopping” without having to go anywhere and even if they do not have enough money to shop. It carries the slogan: "Buy Now Pay Later". However, the use of Spay Later has impacted on its users, both positively and negatively. While the former includes save energy and time because they don't have to leave the house; the latter consists of the emergence of concerns and the tendency to behave consumptively. When the due date is approaching but they have not yet received remittances from their parents, the concerns are mounted because they not only have to pay the total price of the goods, but also pay arrears of 5% of the price of the goods. In addition, with the various conveniences provided by Shopee and Spay Later, shopping depends on the tip of the index finger, when a person cannot control herself, it will be very easy to get caught in consumerism. Therefore, female students must learn to manage their finances and learn to be able to refrain from prioritizing desires over needs.