bluuebunny/crossref_metadata_2025_split huggingface dataset:
A Single Test Protocol to Establish the Full Spectrum of Exercise Intensity Prescription
Authors: IANNETTA DANILO , MACKIE MARY Z. , KEIR DANIEL A. , MURIAS JUAN M. 
Published: November 2023

ABSTRACT
Via the identification of the ramp-specific gas exchange threshold (GET) and respiratory compensation point (RCP), the recently validated step–ramp–step (SRS) protocol enables the prediction of the power outputs at the lactate threshold and maximal metabolic steady state.

Purpose
We aimed to test the extended capabilities of the SRS protocol by validating its capacity to predict the power outputs for targeted metabolic rates (V̇O2) and time-to-task failure (T
lim) within the heavy- and severe-intensity domain, respectively.

Methods
Fourteen young individuals completed (i) an SRS protocol from which the power outputs at GET and RCP (RCPCORR), and the work accruable above RCPCORR, defined as W′RAMP, were derived; (ii) one heavy-intensity bout at a power output predicted to elicit a targeted V̇O2 equidistant from GET and RCP; and (iii) four severe-intensity trials at power outputs predicted to elicit targeted T
lim at minutes 2.5, 5, 10, and 13. These severe-intensity trials were also used to compute the constant-load–derived critical power and W´ (W′CONSTANT).

Results
Targeted (2.41 ± 0.52 L·min−1) and measured (2.43 ± 0.52 L·min−1) V̇O2 at the identified heavy-intensity power output (162 ± 43 W) were not different (P = 0.71) and substantially concordant (CCC = 0.95). Likewise, targeted and measured T
lim for the four identified severe-intensity power outputs were not different (P > 0.05), and the aggregated coefficient of variation was 10.7% ± 8.9%. The derived power outputs at RCPCORR (192 ± 53 W) and critical power (193 ± 53 W) were not different (P = 0.65) and highly concordant (CCC = 0.99). There were also no differences between W′RAMP and W′CONSTANT (P = 0.51).

Conclusions
The SRS protocol can accurately predict power outputs to elicit discrete metabolic rates and exercise durations, thus providing, with time efficiency, a high precision for the control of the metabolic stimulus during exercise.
Impact of COVID‐19 on Indonesia stock portfolio allocation based on a technical & fundamental approach using a machine learning algorithm
Authors: Riyadhi Atha Fitrah , Atok R. Mohamad 
Published: November 2023

Background: COVID-19 has had a negative impact on economic growth in Indonesia and affected the level of investment uncertainty in the Indonesian capital market. Leading stocks with large market capitalization and included in the LQ45 stock index on the Indonesia Stock Exchange (IDX) were also affected by the COVID-19 pandemic, which was corrected by -15% from the pre-pandemic period. This significant decline has a direct negative impact on capital market investors, so as to avoid the Black Swan event that occurred due to the recession, investors need to diversify their portfolios. Methods: Therefore, this study aims to assist investors in better portfolio diversification, especially in the face of the pandemic by using the clustering method. Clustering was carried out on 35 stocks that are members of LQ45 Index from January 1, 2019 to December 31, 2020 based on business fundamental and technical indicators stocks using the K-Means Clustering algorithm. Results: The clustering found that LQ45 stocks are grouped into 4 clusters, each of which have different unique characteristics. Furthermore, the results are used as a reference in stock portfolio allocation where the stocks which have the best sharpe ratio from each selected cluster will be selected to form a portfolio. Conclusion: Portfolio performance testing throughout the market period in 2021 show that formed portfolios are having excellent performance because it has a high positive return and looks much better compared to the LQ45 index as a macro evaluation. In addition, portfolios have also been well diversified, as evidenced by the low correlation value of its inter-stock correlation.
Case Report: Cryoglobulinemic vasculitis after COVID-19 vaccination
Authors: Kechaou Ines , Tekaya Asma , Hamdi Mohamed Salah , Jebri Meryem , Cherif Eya , Ben Hassine Lamia 
Published: November 2023

Since its occurrence, the coronavirus disease 2019 (COVID-19) pandemic has been responsible for a substantial rate of morbidity and mortality. The quick development of an effective and safe vaccine was essential in order to control the ongoing pandemic. However, given the severity of the situation, mass-scale vaccination had to be undertaken without much hindsight. Subsequently, side effects of the anti-COVID-19 vaccine, such as autoimmune diseases, have been reported. Cryoglobulinemic vasculitis (CryoVas) is a rare auto-immune disease, caused by the presence in the serum of abnormal immunoglobulins (cryoglobulins) able to precipitate at temperatures below 37°C. CryoVas can be either essential or, more frequently, secondary to other diseases such as infections, malignancies and auto-immune diseases. In some cases, CryoVas can be vaccine-induced. We describe an original case of a 57-year-old woman with no medical history who presented with purpura of the lower limbs that appeared 5 days after receiving her first COVID-19 vaccine. Skin biopsy and immunological work out were consistent with CryoVas.
Emerging trends and hotspots of Nuclear factor erythroid 2-related factor 2 in nervous system diseases
Authors: Chang Xue-Qin , Xu Ling , Zuo Yi-Xuan , Liu Yi-Guo , Li Jia , Chi Hai-Tao 
Published: November 2023

BACKGROUND
The Nuclear factor erythroid 2-related factor 2 (NRF2) transcription factor has attracted much attention in the context of neurological diseases. However, none of the studies have systematically clarified this field's research hotspots and evolution rules.
AIM
To investigate the research hotspots, evolution patterns, and future research trends in this field in recent years.
METHODS
We conducted a comprehensive literature search in the Web of Science Core Collection database using the following methods: (((((TS=(NFE2 L2)) OR TS=(Nfe2 L2 protein, mouse)) OR TS=(NF-E2-Related Factor 2)) OR TS=(NRF2)) OR TS=(NFE2L2)) OR TS=(Nuclear factor erythroid2-related factor 2) AND (((((((TS=(neurological diseases)) OR TS=(neurological disorder)) OR TS=(brain disorder)) OR TS=(brain injury)) OR TS=(central nervous system disease)) OR TS=(CNS disease)) OR TS=(central nervous system disorder)) OR TS=(CNS disorder) AND Language = English from 2010 to 2022. There are just two forms of literature available: Articles and reviews. Data were processed with the software Cite-Space (version 6.1. R6).
RESULTS
We analyzed 1884 articles from 200 schools in 72 countries/regions. Since 2015, the number of publications in this field has increased rapidly. China has the largest number of publications, but the articles published in the United States have better centrality and H-index. Among the top ten authors with the most published papers, five of them are from China, and the author with the most published papers is Wang Handong. The institution with the most articles was Nanjing University. To their credit, three of the top 10 most cited articles were written by Chinese scholars. The keyword co-occurrence map showed that "oxidative stress", "NRF2", "activation", "expression" and "brain" were the five most frequently used keywords.
CONCLUSION
Research on the role of NRF2 in neurological diseases continues unabated. Researchers in developed countries published more influential papers, while Chinese scholars provided the largest number of articles. There have been numerous studies on the mechanism of NRF2 transcription factor in neurological diseases. NRF2 is also emerging as a potentially effective target for the treatment of neurological diseases. However, despite decades of research, our knowledge of NRF2 transcription factor in nervous system diseases is still limited. Further studies are needed in the future.
Median arcuate ligament syndrome complicated with gallbladder stones: A case report
Authors: Dang Jun-Qiang , Wang Qing-Qiang , Yang Yan-Ling , Shang Lin , Bian Qi-Tian , Xiang Hong-Jun 
Published: November 2023

BACKGROUND
Median arcuate ligament syndrome (MALS) is a rare disease caused by compression of the celiac trunk artery by the median arcuate ligament (MAL). It can cause symptoms of postprandial abdominal pain, weight loss, and nausea and vomiting.
CASE SUMMARY
A 55-year-old woman was admitted due to abdominal pain, nausea and vomiting. On admission, the patient presented with epigastric pain that worsened after eating, without signs of peritoneal irritation. Computed tomography angiography of the upper abdomen showed compression of the proximal segment of the abdominal trunk, local luminal stenosis with angular “fishhook” changes, which changed significantly during forceful inspiration and expiration; gallbladder stones; and multiple cysts in the liver. Abdominal duplex ultrasonography showed that peak systolic velocity was 352 cm/s. After diagnosis of MALS was confirmed, an arch ligament release procedure was performed. MALS has no specific symptoms and can be misdiagnosed as other abdominal diseases. Awareness of MALS should be improved to avoid misdiagnosis. The commonly used treatment option is MAL release and resection of the peripheral ganglion of the celiac trunk artery.
CONCLUSION
The diagnosis and treatment of MALS must be individualized, and MAL release is effective and provides immediate symptomatic relief.
Acoustic characteristics of laser-induced plasmas from the forming dynamics perspective
Authors: Wu Wendong , Chai Shu , Zhou Yuegui 
Published: November 2023

The acoustic signal has demonstrated its capabilities in assisting laser-induced breakdown spectroscopy (LIBS) measurements. In this study, the acoustic characteristics of laser-induced plasmas (LIPs) under different levels of energy deposition were analyzed, and their correlation with LIP forming dynamics was investigated. In the deposited energy space, two zones in the acoustic pressure and duration were observed, featuring a clear transition point in 100 mJ. The analysis based on self-emission spectra and images suggested that this transition is a result of the change in plasma forming dynamics. Above 100mJ, the plasma temperature and electron density were saturated; thus, any further increase in deposited energy only contributes to the plasma size. In this regime, the acoustic wave from the significantly elongated plasma no longer satisfied the ideal spherical assumption. The observation was also strengthened by the analysis in the frequency domain. Moreover, the correlation between acoustic and radiation signals was also changed significantly with plasma forming dynamics. This study offers a systematic analysis of LIP acoustic signals on the deposited energy space. The potential of using acoustic measurement to interpret the plasma forming dynamics was demonstrated, which could be beneficial for the successful implementations of acoustic-aided LIBS.
Taking their wellbeing into their own hands: Self-educated and peer-recommended techniques used by women with breast cancer to improve sexual functioning during treatment and in survivorship
Authors: von Hippel Christiana , Dibble Kate E. , Rosenberg Shoshana M. , Bollman-Jenkins Melissa , Weiss Marisa , Partridge Ann H. 
Published: November 2023

Objective
Coping with sexual dysfunction during and after breast cancer treatment is a persistent challenge for many women, even with clinician-offered standard sexual rehabilitative therapies (i.e., lubricants, counseling). This study sought to explore how women with breast cancer supplement clinician recommendations with self-discovered and peer-recommended techniques for improving sexual functioning and provide insight into how well they work.

Methods
Adult women with stage I-IV breast cancer were recruited to participate in a one-time online survey via Breastcancer.org. Thematic analysis identified emergent domains and themes focused on techniques for improving sexual function during and after treatment. Frequencies were calculated to quantify technique sources and perceived efficacy levels.

Results
Of 501 women responding to the survey, mean age was 53 years (range 30–79). Overall, 34.7% reported using a technique they discovered themselves or that was recommended by someone other than a clinician to improve sexual functioning. Four main themes regarding techniques included: 1) pain reduction, 2) intimacy and relationship enhancement, 3) desire and arousal enhancement, and 4) emotional coping. Most women discovered coping techniques without the help of clinicians, and 45.7% of women rated their techniques as moderately or more effective when used in addition to or instead of standard techniques offered by clinicians.

Conclusions
Our study provides insight into how women with breast cancer successfully cope with sexual dysfunction symptoms during and after treatment. To fully understand and share patients’ innovative techniques for coping with these symptoms, clinicians should foster open discussion about the potential for dysfuction and treatment for these symptoms, as well as avenues of peer-supported discussion to promote coping self-education and discovery.
Effects of 36 hours of sleep deprivation on military-related tasks: Can ammonium inhalants maintain performance?
Authors: Maleček Jan , Omcirk Dan , Skálová Kateřina , Pádecký Jan , Janikov Martin Tino , Obrtel Michael , Jonáš Michal , Kolář David , Michalička Vladimír , Sýkora Karel , Vágner Michal , Přívětivý Lubomír , Větrovský Tomáš , Bendová Zdeňka , Třebický Vít , Tufano James J. 
Published: November 2023

Introduction
A lack of sleep can pose a risk during military operations due to the associated decreases in physical and cognitive performance. However, fast-acting ergogenic aids, such as ammonia inhalants (AI), may temporarily mitigate those adverse effects of total sleep deprivation (TSD). Therefore, the present study aimed to investigate the acute effect of AI on cognitive and physical performance throughout 36 hours of TSD in military personnel.

Methods
Eighteen male military cadets (24.1 ± 3.0 y; 79.3 ± 8.3 kg) performed 5 identical testing sessions during 36 hours of TSD (after 0 [0], 12 [–12], 24 [–24], and 36 [–36] hours of TSD), and after 8 [+8] hours of recovery sleep. During each testing session, the following assessments were conducted: Epworth sleepiness scale (ESS), simple reaction time (SRT), shooting accuracy (SA), rifle disassembling and reassembling (DAS), and countermovement jump height (JH). Heart rate (HR) was continuously monitored during the SA task, and a rating of perceived exertion (RPE) was obtained during the JH task. At each time point, tests were performed twice, either with AI or without AI as control (CON), in a counterbalanced order.

Results
There was faster SRT (1.6%; p < 0.01) without increasing the number of errors, higher JH (1.5%; p < 0.01), lower RPE (9.4%; p < 0.001), and higher HR (5.0%; p < 0.001) after using AI compared to CON regardless of TSD. However, neither SA nor DAS were affected by AI or TSD (p > 0.05). Independent of AI, the SRT was slower (3.2–9.3%; p < 0.001) in the mornings (-24, +8) than in the evening (-12), JH was higher (3.0–4.7%, p < 0.001) in the evenings (-12, -36) than in the mornings (0, -24, +8), and RPE was higher (20.0–40.1%; p < 0.001) in the sleep-deprived morning (-24) than all other timepoints (0, -12, -36, +8). Furthermore, higher ESS (59.5–193.4%; p < 0.001) was reported at -24 and -36 than the rest of the time points (0, -12, and + 8).

Conclusion
Although there were detrimental effects of TSD, the usage of AI did not reduce those adverse effects. However, regardless of TSD, AI did result in a short-term increase in HR, improved SRT without affecting the number of errors, and improved JH while concurrently decreasing the RPE. No changes, yet, were observed in SA and DAS. These results suggest that AI could potentially be useful in some military scenarios, regardless of sleep deprivation.
A Clinicopathologic Comparison Between Early-Onset and Late-Onset Small Bowel Adenocarcinoma: A Multicenter International Study
Authors: Arpa Giovanni , Vanoli Alessandro , Antoci Francesca , Lenti Marco Vincenzo , Di Sabatino Antonio ,   and the Small Bowel Carcinoma Consortium
Published: November 2023

INTRODUCTION:
Early-onset small bowel adenocarcinoma (EO-SBA) is a rare and poorly characterized entity.

METHODS:
This retrospective study conducted on an international multicenter cohort of 208 patients with SBA aimed at comparing clinicopathologic features of EO-SBA (age younger than 50 years at SBA diagnosis) and late-onset SBA (age 50 years or older at SBA diagnosis).

RESULTS:
The presence of predisposing pathologic conditions was significantly more common in the EO-SBA group compared with that in the late-onset SBA group (P = 0.003, Fisher exact test; relative risk: 1.50, 95% confidence interval: 1.20–1.86). This difference is mainly due to the significantly higher prevalence of celiac disease among patients with EO-SBA.

DISCUSSION:
EO-SBA is strongly associated with predisposing conditions, particularly with celiac disease, highlighting the importance of routine screening for celiac disease in patients with EO-SBA.
A HEI strategy to implement solutions aligned with energy and climate change challenges
Authors: Nazaré Loraine , Fernandes Inês , Oliveira Joaquim , Lillebø Ana , Queirós Alexandra 
Published: November 2023

The vision of the University of Aveiro (UAveiro) is “to create, share and apply knowledge, involving the whole community through teaching, research, and cooperation with the surrounding environment, in order to make a clear difference for individuals and society”. Framed in the concept of Sustainability and Intergenerational Justice, UAveiro has has act by stimulating behaviours towards sustainability and by implementing solutions aligned with energy and climate change challenges. Relevant examples are a manual of good environmental sustainability practices, dashboards to monitor our performance, University Footprint Calculator that enables “to think and anticipate realities” towards carbon neutrality without compromising future generations, UAUBike, solutions for sustainability challenges, the greenbuilding’s project.This paper showcases, from different perspectives, the role of UAveiro to contribute to tackle societal challenges arising from the climate crisis and global changes and promote transformative solutions in favour of sustainability, social responsibility and climate action.
Practices Towards an Effective Response to Climate and Energy Challenges in The Al-Muthanna University Campus
Authors: Kbah Ahmed A. Rashid , Alsallal Muna , Al-Mur'Ib Hadel Saad Razoki , Al-Rubay Ali Saad 
Published: November 2023

Regarding the UN reports, Climate change adaptation and mitigation stands for the most difficult challenge for the current and subsequent years in the world, in addition to the particular case of Iraqi cities, especially with the dry, hot climate and Power generation problems. Al-Muthanna University, during the last five years, focused on using the essential tools depending on NBS for saving energy (using daylight, rainwater, and natural materials) and also using innovative solutions (led light, sensors, solar panels, remote sensing) for reducing energy consumption in the Campus, Greenhouse gas emission the University reduce it by reducing the energy consumption itself, encouraging staff to use Liquid Gas Fuel Automotive, increase the green area, cycling. Therefore, the approximate use of energy-efficient applicants (particularly LED lamps and laptops) is around 75%. It is also good to mention that there is a total area of smart buildings of 82150 m2 across all campuses of Al-Muthanna University. In addition, the total Carbon footprint in 2021 equals 90.83 metric tons.
Strategic Incorporation of Experiential Learning in Sustainability Through the Project “Path to A Sustainable Country”
Authors: Dulce Claudia , Díaz Andrea 
Published: November 2023

Path to a Sustainable Country (in Spanish “Ruta País Sostenible”) is an institutional commitment that seeks to reinforce the importance of natural resources in the university community and promote learning based on experience. We make field trips around the country that connect nature and communities. The areas selected are the National Natural Parks (NNP) and the protected areas of Colombia (12% of the country's territory). This project has the intention to be closer to the territory´s realities. At the same time, we have an experiential analysis to develop academic projects that promote the conservation of ecosystem services, and the improvement of the quality of life of the surrounding communities. Since 2022, we have made three field trips to the NNP: Chingaza (paramo), Bahía Málaga (mangrove), Desierto de la Tatacoa (tropical dry forest), El Zoque (andean forest), El Cocuy (Glacier). On those trips, we have had 150 participants among students, professors, staff, and alumni. We tested the most appropriate and effective sustainable learning process. The result indicated that 50% of people memorize the concepts when they directly observe nature and communities. Meanwhile, the second most successful tool was applied research (20%), followed by classes (16%), and finally, laboratory practices (14%).
TÜRKİYE'S SOFT POWER IN THE BALKANS & KOSOVO CASE
Authors: KETENCİ Ayşegül 
Published: November 2023

States have important effects on each other, factors such as history, language, culture, belief, geography, and common history are the main components that provide this effect. During the Ottoman period, a large Turkish population lived in the Balkans, the Balkans was very important for the Ottomans geopolitically. The young Turkish Republic embarked on reforms within the country after the War of Independence, failed to maintain sufficient connections and soft power in the Balkans during the Second World War and the Cold War, but the situation changed after the Cold War. With the disappearance of the Soviet threat and Türkiye's desire to pursue a more active foreign policy, the Balkans once again became very important. The Balkans has a dense Turkish population, is Türkiye's open door to Europe, and is closely linked to Türkiye by common historical and cultural ties.
In the study, Türkiye 's efforts to increase its soft power in the Balkans after the Cold War was examined. While examining the study, the example of Kosovo, one of the most fragile countries in the Balkans, will be detailed. In the study, it is aimed to evaluate the results of these efforts by considering the policies implemented by Türkiye to be effective in the Balkans after the end of the Cold War, the activities of TIKA and Yunus Emre Institute, and Türkiye's soft power in Kosovo / efforts to increase this power.The policies implemented by Türkiye have made significant contributions to the stability of Kosovo, especially the Balkans, and to the development of mutual education, culture and social ties. This situation has had important consequences for Kosovo's integration with the Western alliances, and it is an indication that Türkiye uses its soft power policies as an effective tool in the Balkans.