bluuebunny/crossref_metadata_2025_split huggingface dataset:
Childcare burden and changes in fertility desires of mothers during the COVID-19 pandemic
Authors: Golovina Kateryna , Nenko Ilona , Marcinkowska Urszula Maria 
Published: November 2023

ObjectivesPrevious studies have documented a decline in fertility desires and intentions following the COVID-19 outbreak, but the reasons for this decline are not well understood. This study examined whether childcare burden on mothers during the lockdown and quarantines, COVID-related stress, and COVID exposure were associated with a change in the desired number of children.MethodsThe survey was conducted online, in Poland from April to July 2021 on a sample of 622 non-pregnant mothers without diagnosed infertility.ResultsAssociations were observed between childcare responsibilities during the quarantine and fertility desires: mothers who solely or mainly took care of their children during the quarantine(s) were more likely to decrease their desired number of children ([adjusted] aOR = 1.91, 95% CI = 1.16–3.15). Mothers with higher levels of COVID-related stress (aOR = 1.81, 95% CI = 1.48–2.22) and a greater COVID exposure index (aOR = 1.39, 95% CI = 1.12–1.72) were more likely to decrease their fertility desires.ConclusionHigher childcare burden during quarantines was related to a lower desired number of children among mothers. Both greater COVID-related stress and COVID exposure were associated with fertility desires, regardless of childcare responsibilities during the pandemic.
Nurturing resilience in American Indian/Alaska Native preschool children: the role of cultural socialization, executive function, and neighborhood risk
Authors: Merculief Alexis , Lipscomb Shannon , McClelland Megan M. , Geldhof G. John , Tsethlikai Monica 
Published: November 2023

IntroductionAmerican Indian and Alaska Native (AI/AN) children possess numerous cultural assets, yet higher exposures to neighborhood risks (e.g., lack of housing, crime) may present barriers to healthy cognitive development, including executive function (EF). Cultural socialization may promote resilience and support children’s early cognition, but this has not been adequately studied. The present study examined the effects of neighborhood risk and cultural socialization on EF for AI/AN preschool children.MethodParents/caregivers of 768 AI/AN preschoolers from the 2015 AI/AN Head Start Family and Community Experiences (FACES) Study rated neighborhood risk via two scales: “Neighborhood Problems” and “Environmental Conditions,” and cultural socialization practices via two scales: cultural activities and tribal language activities. Children’s EF was measured directly using the Pencil Tap Task and the Leiter-R attention subscale.ResultsFamilies perceived neighborhood risks as relatively low, and overall risk did not predict children’s EF. However, higher average language socialization was significantly related to higher EF, as were two specific language activities (encouraging children to learn their tribal language, making sure children heard their tribal language) and two cultural activities (playing AI/AN games, participating in tribal ceremonies), controlling for neighborhood risk.DiscussionFindings suggest some aspects of cultural socialization may promote resilience among AI/AN preschoolers by supporting early EF. Mechanisms may include increased spiritual, social, and cultural connections, and practice with EF skills during cultural games. Future research should partner with AI/AN communities to investigate culturally grounded EF interventions and reevaluate measures of neighborhood risk to promote resilience and connectedness for AI/AN children.
A randomized controlled trial of a targeted support program for informal caregivers in adult psychiatry
Authors: Rexhaj Shyhrete , Martinez Debora , Golay Philippe , Coloni-Terrapon Claire , Monteiro Shadya , Buisson Leslie , Drainville Anne-Laure , Bonsack Charles , Ismailaj Alban , Nguyen Alexandra , Favrod Jérôme 
Published: November 2023

BackgroundThe importance of informal caregivers for persons with severe mental illness has been demonstrated. However, this role may cause a high care burden that considerably affects caregiver health. The Ensemble program is a five-session brief individual intervention designed to support informal caregivers. This trial aimed to assess the efficacy of the program versus SAU (support as usual) for participants with a high care burden.MethodsA single-center randomized controlled trial including 149 participants was conducted. Caregivers in the intervention arm participated in the Ensemble program. The effects of the intervention were assessed using mixed models for repeated measures analysis of variance on improvements in informal caregivers’ psychological health status, optimism levels, burden scores, and quality of life at three time points (T0 = pretest; T1 = posttest at 2 months, and T2 = follow-up at 4 months).ResultsAnalysis of the Global Psychological Index showed no significant effect at the two endpoints in favor of the Ensemble group. However, the Brief Symptom Inventory-Positive Symptom Distress Index was significantly lower at the two-month follow-up. A significant reduction in burden on the Zarit Burden Interview was observed post-intervention, along with an increase in optimism levels on the Life Orientation Test-Revised at follow-up in the Ensemble group. No significant differences were observed in quality of life. Clinical improvements in both psychological health status and burden levels were also identified.ConclusionThe Ensemble program offers an inclusive approach based on a recovery perspective that significantly reduces symptom distress and burden and increases optimism among informal caregivers.Clinical trial registration: https://clinicaltrials.gov/, NCT04020497.
A rapid review of best practices in the development of risk registers for public health emergency management
Authors: Kostirko Danylo , Zhao Jiawei , Lavigne Melissa , Hermant Benoit , Totten Liam 
Published: November 2023

IntroductionPublic health organizations (PHO) must prepare to respond to a range of emergencies. This represents an ongoing challenge in an increasingly connected world, where the scope, complexity, and diversity of public health threats (PHT) have expanded, as exemplified by the COVID-19 pandemic. Risk registers (RR) offer a framework for identifying and managing threats, which can be employed by PHOs to better identify and characterize health threats. The aim of this review is to establish best practices (BP) for the development of RRs within Public Health Emergency Management (PHEM).MethodsIn partnership with a librarian from Health Canada (HC), and guided by the Cochrane Rapid Review Guideline, journal articles were retrieved through MEDLINE, and a comprehensive search strategy was applied to obtain grey literature through various databases. Articles were limited to those that met the following criteria: published on or after January 1, 2010, published in the English language and published within an Organisation for Economic Co-operation and Development setting.Results57 articles were included for synthesis. 41 papers specifically discussed the design of RRs. The review identified several guidelines to establish RRs in PHEM, including forward-looking, multidisciplinary, transparent, fit-for-purpose, and utilizing a systems approach to analyze and prioritize threats. Expert consultations, literature reviews, and prioritization methods such as multi-criteria-decision-analysis (MCDA) are often used to support the development of RRs. A minimum five-year-outlook is applied to assess PHTs, which are revisited yearly, and iteratively revised as new knowledge arises.DiscussionBased upon this review, RRs offer a systems approach to PHEM that can be expanded to facilitate the analysis of disparate threats. These approaches should factor in the multidimensionality of threats, need for multi-sectoral inputs, and use of vulnerability analyses that consider inherent drivers. Further research is needed to understand how drivers modify threats. The BPs and recommendations highlighted in our research can be adopted in the practice of PHEM to characterize the public health (PH) risk environment at a given point in time and support PHOs policy and decision-making.
Bacillus subtilis engineered for aerospace medicine: a platform for on-demand production of pharmaceutical peptides
Authors: Vallota-Eastman Alec , Bui Cynthia , Williams Philip M. , Valentine David L. , Loftus David , Rothschild Lynn 
Published: November 2023

Biologics, such as pharmaceutical peptides, have notoriously short shelf lives, insufficient for long-duration space flight missions to the Moon or Mars. To enable the sustainable presence of humans on the Moon or Mars, we must develop methods for on-site production of pharmaceutical peptides in space, a concept we call the Astropharmacy. Here, we present a proof-of-concept for the first step needed: a low-mass system for pharmaceutical production designed to be stable in space. To demonstrate feasibility, we engineered strains of the space-hardy spore-forming bacterium, Bacillus subtilis, to secrete two pharmaceutical peptides important for astronaut health: teriparatide (an anabolic agent for combating osteoporosis) and filgrastim (an effective countermeasure for radiation-induced neutropenia). We found that the secretion peptides from the walM and yoqH genes of B. subtilis worked well for secreting teriparatide and filgrastim, respectively. In consideration of the Translational Research Institute for Space Health (TRISH) challenge to produce a dose equivalent in 24 h, dried spores of our engineered strains were used to produce 1 dose equivalent of teriparatide from a 2 mL culture and 1 dose equivalent of filgrastim from 52 mL of culture in 24 h. Further optimization of strain growth conditions, expression conditions, and promoter sequences should allow for higher production rates to be achieved. These strains provide the template for future optimization efforts and address the first step in the Astropharmacy, capable of on-site production, purification, and processing of biopharmaceutical compounds in platforms amenable for use in space.
The prevalence and risk factors of dental disease found in 100 miniature horses
Authors: Tinsley Tracy , Fogle Callie , Means Elaine , Robertston James 
Published: November 2023

IntroductionDental disease is a common condition affecting horses. Its prevalence and characteristics among most of the common breeds of horses and donkeys have been investigated and described in the literature, but information about the prevalence and etiology of dental disease of miniature horses is sparse.MethodsTo determine the prevalence and characteristics of dental disease of miniature horses, we performed oral and dental radiographic examinations on 100 miniature horses. The findings of these examinations were analyzed to determine the prevalence of dental disease and its correlation to age, sex, weight, body condition score, height at the withers, head length and head width. Older horses had a higher prevalence of dental disease, diastemata and crown elongations.ResultsThe most common dental diseases detected in this population were crown elongation, oral mucosal ulceration, diastemata, class 1 malocclusion and hypodontia. Horses with a high body condition score had an increased likelihood of having a class 1 malocclusion. Horses with wider heads had a higher prevalence of dental disease and class 1 malocclusions.ConclusionFrequent oral examinations, starting at an early age, should be prioritized as a part of miniature horse preventive health care to decrease morbidity and slow progression of dental disease.
Zero- to One-Dimensional Zn24 Supraclusters: Synthesis, Structures and Detection Wavelength
Authors: Chen Yating , Chen Zhonghang , Wang Jiming , Ma Xuandi , Yuan Linyu , Zhang Shuhua , Tang Fushun 
Published: November 2023

A zinc supracluster [Zn24(ATZ)18(AcO)30(H2O)1.5]·(H2O)3.5 (Zn24), and a 1D zinc supracluster chain {[Zn24(ATZ)18(AcO)30(C2H5OH)2(H2O)3]·(H2O)2.5}n (1-D⊂Zn24) with molecular diameters of 2 nm were synthesized under regulatory solvothermal conditions or the micro bottle method. In an N,N-dimethylformamide solution of Zn24, Fe3+, Ni2+, Cu2+, Cr2+ and Co2+ ions exhibited fluorescence-quenching effects, while the rare earth ions Ce3+, Dy3+, Er3+, Eu3+, Gd3+, Ho3+, La3+, Nd3+, Sm3+, and Tb3+showed no obvious fluorescence quenching. In ethanol solution, the Zn24 supracluster can be used to selectively detect Ce3+ ions with excellent efficiency (limit of detection (LOD) = 8.51 × 10−7 mol/L). The Zn24 supracluster can also detect wavelengths between 302 and 332 nm using the intensity of the emitted light.
Potential of Reinoculation Using R. tropici Applied under Cover to Increase Bean Yield
Authors: Lourenço Amanda E. , Teixeira Itamar R. , Rocha Ednaldo C. , Silva Gisele C. , Reis Elton F. , Santos Fenelon L. , Silva Guilherme R. , Lisboa Cristiane F. , Kikuti Hamilton , Silva Alessandro G. 
Published: November 2023

The common bean is known to require nitrogen, with mineral fertilizer being the main form of supply to the plants. However, more efficient inoculants containing strains of Rhizobium tropici that are potentially more efficient in fixing atmospheric N2 could replace the use of nitrogen fertilizers as long as some of the existing challenges in the application methodology are overcome (for example, ensuring the existence of active nodules in the most demanding crop phases: flowering and grain filling). This study aimed to verify the responses of common bean plants subjected to reinoculation using Rhizobium tropici in topdressing applied at different stages in a greenhouse and in a field between March and April 2020 and in the spring–summer harvest of 2020/2021, respectively. A randomized block design was used, along with four replications: T1 = uninoculated control; T2 = inoculation via seed (VS); T3 = VS + reinoculation at the V4 stage; T4 = VS + reinoculation at the R5 stage; T5 = VS + reinoculation at the R6 stage; T6 = VS + reinoculation at the V4 and R5 stages; T7 = VS + reinoculation at the V4 and R6 stages; T8 = VS + reinoculation at the R5 and R6 stages; T9 = VS + reinoculation at the V4, R5, and R6 stages; and T10 = mineral nitrogen fertilization. Nodulation and morphological variables were evaluated at the R7 stage, and agronomic variables were evaluated at the R9 stage at harvest. The use of reinoculation, in addition to inoculation, positively influenced the bean nodulation process. The morphological characteristics of the plants showed good development with the supply of N (carried out via inoculation and reinoculation), equivalent to the development that could be achieved via the addition of a mineral nitrogen fertilizer. Reinoculation from the R5 to R7 stages proved ineffective in supplying N to the common bean crop. Inoculation in the seed associated with reinoculation in coverage at the V4 stage provided higher yields (3.271 kg ha−1), reinforcing the potential for mineral nitrogen fertilizers to be replaced. The use of the seed inoculation technique with subsequent reinoculation under cover can completely replace the use of nitrogenous mineral fertilizers in fertilizing bean plants, making the cultivation of this fabacea more sustainable in terms of the associated costs and environmental problems.
Digital financial market architecture
Authors: Frumina S. V. , Galanov V. A. 
Published: November 2023

The Russian Federation is one of the world leaders in financial technologies used in various segments of the financial market. The digitalization of the payment system, the development of digital banking and other fintech solutions are fundamentally transforming the architecture of the financial market. Undoubtedly, the digital financial market is being formed on the basis of the existing and proven architecture for decades. However, the changes associated with digitalization will naturally lead to its progressive transformation.The digitalization of the financial market will allow uniting its separately existing parts into a single organizational structure, forming a single centralized digital market. The formation of a single digital space will make it possible to erase the boundaries between financial market segments.The research methodology is based on general scientific dialectical methods (analysis and synthesis, deduction and induction). The purpose of the article is to acquaint the reader with the natural transformations of the financial market, which radically change its architecture and lead to the formation of a single digital financial market.
Analisis Efisiensi Produksi Padi di Desa Tunjung, Kecamatan Burneh, Kabupaten Bangkalan Menggunakan Pendekatan Frontier 4.1
Authors: Musyafak Musyafak , Lestari Fany Etana , Setianingrum Khusnul Rahmah , Widiastuti Sri 
Published: November 2023

Kecamatan Burneh adalah kecamatan yang berada di Kabupaten Bangkalan yang memiliki pengembangan sektor pertanian yang cukup baik. Hal ini dikarenakan adanya Bendungan Dam Tunjung Burneh yang mengaliri kawasan persawahan di Kecamatan Burneh, termasuk Desa Tunjung. Desa Tunjung adalah desa yang memiliki jumlah petani cukup tinggi yaitu sebanyak 266 petani. Namun, disamping memiliki hasil produksi padi yang tinggi, terdapat permasalahan yang menghambat petani padi Desa Tunjung dalam menjalankan usahataninya. kurang efisiensinya dalam usahatani padi. Permasalahan tersebut yaitu kurangnya efisiensi biaya dalam menjalankan usahatani dan lahan pertanian yang sempit dan terbatas. Oleh sebab itu, perlu adanya penelitian guna menganalisis efisiensi usahatani padi di daerah tersebut. Penelitian ini bertujuan untuk menganalisis efisiensi teknis dan efisiensi ekonomis usahatani padi di Desa Tunjung serta mengidentifikasi faktor-faktor sosial ekonomi penyebab terjadinya inefisiensi teknis dan ekonomis udahatani padi di Desa Tunjung. Penelitian dilaksanakan di Desa Tunjung dengan metode analisis efisiensi produksi menggunakan fungsi produksi stochastic frontier cobb douglas sejumlah 60 sampel petani. Hasi penelitian menunjukkan bahwa 60% petani padi di Desa Tunjung dikatakan efisien secara teknis sedangkan sisanya yaitu 40% tidak efisien secara teknis. Rata-rata efisiensi alokatif serta efisiensi ekonomi usahatani padi di Desa Tunjung belum dapat mencapai efisien, secara keseluruhan (60 petani) tidak efisien yaitu sebesar 0.745 dan 0.733 (< 0,8).
Sistem Informasi Manajemen Surat Menyurat Berbasis Web Menggunakan Metode Waterfall Di Desa Bodeh Kecamatan Randublatung Kabupaten Blora
Authors: Dika Ade Royani  , Abdul Rohman  
Published: November 2023

Kantor Desa Bodeh adalah suatu instansi Pemerintah yang bertugas melaksanakan kewenangan pemerintahan. Berdasarkan catatan, termasuk memproses surat masuk dan keluar secara manual, tidak semua surat terarsip dengan baik, dan tindak lanjut dari disposisi kepala departemen terkait yang kadang menyita banyak waktu, serta surat yang hilang. Metode pengumpulan data yang digunakan penulis dan untuk pengembangannya menggunakan metode waterfall. Berdasarkan apa yang akan terjadi sistem informasi berjalan dengan baik dengan pengujian yang dilakukan menggunakan rentang nilai 100% Blackbox.

Kata Kunci: Manajemen, Surat, Arsip, Desa
Tumor venéreo transmissível nasal em cão - relato de caso
Authors: Dall’agnol Janaina Carolina Cabral , Oliveira Rafael Rocha de , Godoi Maiara Aparecida Rodrigues de , Vieira Thaís Badini 
Published: November 2023

O Tumor venéreo transmissível (TVT) é uma neoplasia de células redondas e indiferenciadas que acomete cães de qualquer raça, idade e sexo. A transmissão do TVT ocorre através da implantação de células tumorais viáveis na superfície das membranas mucosas durante a cópula ou em outros locais do corpo do animal através de arranhaduras, lambeduras ou contato direto com o tumor. Quando o TVT se encontra em cavidade nasal pode ocorrer aumento de volume local, dispneia, epistaxe, secreção purulenta ou serosanguinolenta e deformidade do osso nasal. O presente trabalho tem como objetivo relatar um caso de TVT canino em cavidade nasal, tratado com sulfato de vincristina e ozonioterapia. No exame clínico foram observados: espirros, apatia, secreção nasal serosanguinolenta, dispneia, úlcera em palato mole, enfisema na região de pescoço, aumento de volume na região do osso nasal com presença nódulos circulares de aspecto ulcerativo, friável e sanguinolento, presença de hematomas e escoriações do lado direito da face. Após o exame clínico realizou-se hemograma, raio X de crânio e citologia por punção aspirativa com agulha fina, confirmando o diagnóstico de TVT. Para o tratamento, foram administradas seis aplicações de sulfato de vincristina na dose de 0,5mg/m² de superfície corporal, via intravenosa, em intervalos de 7 dias. Durante os 13 dias de internação foram realizadas seis sessões de ozonioterapia por via subcutânea próxima à lesão do focinho e por via retal. Após a alta, o animal recebeu acompanhamento semanal com quimioterápico e ozonioterapia, observando-se redução total do tumor em 40 dias.
Dinámicas de participación y comunicación en la gestión educativa en tiempos de crisis: perspectivas desde una comunidad de Mórrope (Perú)
Authors: Bussalleu Daniela , Mateus Julio-César 
Published: November 2023

En el marco de una crisis sanitaria, el único órgano local encargado de promover la participación ciudadana en la gestión educativa, el Consejo Participativo Local de Educación (Copale), estuvo inactivo. Este fue el punto de partida para explorar las formas de comunicación y participación en la gestión educativa de una comunidad en Mórrope, distrito situado al norte del Perú, durante la pandemia de la COVID-19. A partir de un enfoque fenomenológico-cualitativo basado en entrevistas y análisis documental se revelaron procesos de participación e interacciones comunicacionales naturales no regulatorias, evidenciando escenarios positivos, como el papel de los actores comunitarios al abordar diversos problemas logísticos: búsqueda de estudiantes «no contactados», distribución de alimentos de Qali Warma o desarrollo de las sesiones de aprendizaje virtual. Sin embargo, se observaron también escenarios negativos como las prácticas comunicativas verticales desde el Estado. Finalmente, se examinó la percepción de los directivos de la Unidad de Gestión Educativa Local (UGEL) sobre la participación ciudadana, contrastándola con la realidad observada. Las experiencias recopiladas destacan la importancia de la participación comunitaria como eje en la gestión educativa e invitan a repensarla no solo como un conocimiento directo de las necesidades locales, sino como una cuestión de justicia social.
PENGARUH PENGGUNAAN MEDIA PEMBELAJARAN WORDWALL UNTUK MENINGKATKAN KEAKTIFAN BELAJAR PESERTA DIDIK PADA MATA PELAJARAN PENDIDIKAN PANCASILA KELAS IV SDN TLOGOSARI WETAN 01 SEMARANG
Authors: Kunti Shouma Tsaniya  , Olivia Zakkia Nafis  , Frisca Eman Rosaifa  , Susilo Tri Widodo  , Nur Indah Wahyuni  
Published: November 2023

Boredom becomes common in the monotonous learning process. Especially in teacher-centered learning alone without any interesting innovations. Therefore, creativity and innovation are needed in driving away boredom and fostering interest in learning in students. With the existence of interesting learning media, it will certainly encourage students to be more enthusiastic in the learning process. The purpose of this study is to determine how much influence the use of wordwall media has on increasing student learning activity in grade IV pancasila education subjects SDN Tlogosari Wetan 01. The research method used in this study is quantitative experiment. This research was carried out during two meetings where in the first meeting it became a control class where in the first meeting researchers still used conventional learning and only used learning videos while in the second meeting became an experimental class, namely researchers using wordwall learning media. The results of research that have been conducted show an increase in student activeness by 55.56%. From these results, it indicates that the use of wordwall-based interactive media can increase student learning motivation effectively and significantly.