bluuebunny/crossref_metadata_2025_split huggingface dataset:
A new type of single-arm single-port micro-trauma laparoscopic surgery robot
Authors: QU Jichen , JIANG Naijing , CHEN Liangliang , He Chao , FAN Jiang , ZHAO Yaping 
Published: January 2024

Abstract
As the robot-assisted single-port surgery gets more attention, we proposed a novel single-arm single-port micro-traumatic laparoscopic surgery robot system with multiple innovative techniques. From a mechanical perspective, joints with high rigidity and reliability were used to realize the remote center of motion. The cost of consumables was reduced by adding the support of a rigid endoscope. From the algorithm perspective, a high-precision motion control method and feedback-force protection mechanism were implemented. The effectiveness of the aforementioned characteristics was verified by 10 clinical cholecystectomy experiments. The results showed that the system can reduce the amount of bleeding, accelerate patient recovery, reduce infection risk, and shorten the learning period. Other gynecology and urology clinical trials using the new surgery robot are underway. The proposed surgery robot system had significant clinical application value.
Is personality reflected in gestures?
Authors: Lopez-Ozieblo Renia 
Published: January 2024

Abstract
Previous studies on gestures and personality suggest an ambiguous picture of the effects of the various personality dimensions on the different types of speech gestures and adaptors. In foreign language learning an additional variable to take into account is proficiency, which some studies have shown to affect gestures. In this study we explore how various intrinsic variables, including personality, proficiency, gender and age affect the gestures of 61 Cantonese speakers of English as a second language. Participants were asked to narrate a video cartoon. Their proficiency and the frequency of gestures produced was based on those narrations. A functional categorization of gestures was followed, dividing them into semantic and discursive, and also noted adaptors and micro-gestures, referred to as “flutters”. Personality was self-reported using the 44 question Big-Five inventory. Correlations and a series of generalized linear models were developed to explore the interplay between variables. Significant correlations found agreeableness, positively correlated with semantic gestures; and neuroticism and age negatively correlated with flutter duration. Extraversion was positively related to adaptor duration, although this was not reflected in the models. Contrary to the findings from previous studies, no significant relationships were found between neuroticism and adaptors or semantic gestures, nor between extraversion or openness and semantic gestures. Proficiency and gender had little effect on gestures. None of the models are very strong, suggesting that other variables, aside from the those tested, should be considered. The results suggest that anxiety might have a greater impact on gesture production rather than proficiency or personality.
Enhancing the Security of Vigenere and Polybius Hybrid Cryptography System using Modified Linear Congruential Generation Algorithm
Authors: Muhammed Alemu Jorgi , Tsegaye Getaneh Geto , Woldegiorgis Tefera Alagaw 
Published: January 2024

Abstract
In the arena of security, various encryption algorithms are used to protect information transmitted through insecure channels. Employing a hybrid encryption algorithm provides a strong defense and complicates the decryption process for potential intruders. A hybrid cipher system that combines the Vigenere and Polybius ciphers has proven to be more secure than each cipher alone. One strategy to bolster cipher security involves generating distinct cipher text results for the same plain text and key during different instances. However, hybrid algorithm faces vulnerable to different cryptanalysis attacks such as frequency analysis attack, brute force attack and dictionary attack due to the use of repeating nature of the Vigenere key and unmodified Polybius table for encryption. To address these challenges, we propose an algorithm introducing dynamic cipher text, a random key generated through a modified linear congruential generation algorithm, and a randomized Polybius table for each character using the Randi function. Simulation results demonstrate that the proposed algorithm achieves enhanced security metrics, supporting a 96% of avalanche effect, improved confusion and diffusion properties, a mere 1.54 % average occurrence of character in the cipher text, and a 0.01839 index of coincidence value. Therefore, the proposed algorithm outperforms existing hybrid algorithms in terms of security.
Vegetation Structure and Carbon Storage of Natural and Restored Mixed Deciduous Forests in Western Thailand
Authors: CHANLABUT UTAIN , CHANKIAN JEERAPORN , HIRUN DUSSADEEPORN , AUANSRIMUANG WICHUTA , NAHOK BENCHAWAN 
Published: January 2024

Abstract
Anthropogenic disturbances are important factors in the dynamics of forests, altering forest structure and carbon storage. This study compared the vegetation structure and forest carbon storage of two tropical mixed deciduous forest sites with different disturbance histories: natural forest (NF) and restored forest (RF). Field surveys and sampling were conducted in April 2022. The NF had significantly higher tree height and basal area than the RF, indicating a more mature and complex forest structure. The two forest communities had 49% similarity in species composition, but the NF was more diverse than the RF and had different dominant species. The J-shaped pattern of forest structure suggested that both communities were in a progressive and healthy stage of development. The NF also had higher aboveground biomass, aboveground carbon, and total carbon storage than the RF, resulting in a greater potential for CO2 sequestration. The insignificant differences in some forest parameters between the restored and natural forests indicated that the restored forests were gradually recovering to their natural condition after decades of restoration. However, other parameters showed that these areas still lacked certain functions due to a history of severe disturbances. These findings suggest that the restoration of degraded forests can lead to the recovery of important ecological parameters, such as forest structure, carbon storage, and tree diversity. However, the recovery process may take several decades, depending on the severity of the degradation and the management practices that are applied.
Bioinformatics Approach to Identify the Pathogenetic Link of Gut Microbial Metabolites and Stroke
Authors: Ding Liang , Wang Jianing , Qiu Sha , Ren Zhizhen , Yuantao Li , An Pengpeng 
Published: January 2024

Abstract
Stroke is a life-threatening condition that impairs the arteries and causes neurological impairment. The incidence of stroke is increasing year by year with the arrival of the aging population. Thus, there is an urgent need for early stroke diagnosis. Short-chain fatty acids (SCFAs) can modulate the central nervous system and directly and indirectly impact behavioral and cognitive functions. This study aimed to investigate the connection between SCFA metabolism and stroke development via bioinformatic analysis. Initially, the GSEA and immune cell infiltration analysis were performed based on RNA data from stroke patients to comprehend the mechanisms governing stroke pathogenesis. The functional analysis, including GO, KEGG, and PPI, was performed based on the DEG selected by the limma package. 1220 SCFA metabolism-related genes screened from Genecards databases were intersected with 242 genes in main modules determined by WGCNA, and the final 10 SCFAs key genes were obtained. GO analysis revealed that these genes were involved in immune response processes. Through lasso regression analyses, we established a stroke early diagnosis model and selected 6 genes with diagnostic value. The genes were validated by the AUC values and had a relatively good diagnostic performance. Finally, 4 potential therapeutic drugs targeting these genes were predicted using the DSigDB via Enrichr. In conclusion, this paper analyzes the involvement of SCFAs in the complex gut-brain axis mechanism, which contributes to developing new targets for treating central nervous system diseases and provides new ideas for early stroke diagnosis.
Investigating new inhibitors with potential advantages for combating HER2-overexpressing head and neck squamous cancer cells; a practical and virtual screening study
Authors: Zeinali Majid , Pourshohod Aminollah , Barzegari Ebrahim , Akbari Akbar , Absalan Forouzan , Mehranfar Amir , Jamalan Mostafa 
Published: January 2024

Abstract
Head and neck squamous cell carcinoma (HNSCC) are between most common cancer worldwide. Most HNSCC tumors are characterized by higher expression of human epidermal growth factor receptor 2 (HER2) that is related to resistance to chemotherapy and radiotherapy. Accordingly, HER2 has been proposed as a fair target for specific chemotherapy. Lapatinib as a potent inhibitor of the EGFR family were proposed for the treatment of HER2-positive HNSCC cases. In current study, at first step we used the crystal structure of HER1-lapatinib complex (PDB ID: 1XKK) to deeply investigate lapatinib interaction with HER1. Based on the HER1-lapatinib crystal structure and conserved structure of EGFR family, we made a confirmed coordination to survey HER2-lapatinib interactions. After investigation of lapatinib with HER1 and HER2 structures via docking approach, we evaluated lapatinib effect on HN5 cells as HER2-overxpressing HNSCC-originating cell line. At last, we used created 3D coordination to introduce other efficient and specific inhibitors for HER1 and HER2 based on virtual screening processing according on structural similarity to lapatinib. Also, Pharmacokinetic properties of indicated ligands were assessed by ADMET in silico modelling tool. Obtained results showed, in accordance with our obtained docking result while the presence of lapatinib could enhance the optimum effect of cisplatin on ablation of HN5 cells it could not empower the specific effect of cisplatin on HN5 cells when compared with normal HER2-expressing MCF-7 cells. Following, based on virtual screening process, we introduce agents with high and specific affinity for HER1 and HER2.
A comparison of field portable X-ray fluorescence (FP XRF) and inductively coupled plasma mass spectrometry (ICP-MS) for analysis of metals in the soil and ambient air
Authors: Schmidt Kelsey , Autenrieth Daniel , Nagisetty Raja 
Published: January 2024

Abstract
When analyzing metal concentrations in the soil and ambient air, accurate and reliable results are essential. Inductively coupled plasma mass spectrometry (ICP-MS) is considered the benchmark analytical method for environmental soil and air filter samples containing metals. Field portable X-ray fluorescence (FP XRF) can provide more timely results with lower ongoing costs, but the results are not as accurate as ICP-MS. The primary goal of this study was to find an optimal method to maximize the level of agreement between FP XRF results and ICP-MS results when analyzing metal concentrations in soil and ambient air samples in a U.S. Superfund community. Two different correction factor methods were tested to improve the prediction of ICP-MS concentrations using FP XRF for arsenic and lead in soil and ambient air. Ninety-one residential soil samples and 42 ambient air filter samples were analyzed in a split-half design, where half the samples were used to create the correction factors and the other half to evaluate the level of agreement between the analytical methods following FP XRF correction. Paired t-tests, linear regression plots, and Bland-Altman plots were utilized to examine which correction factor provided the highest level of agreement between the two methods. Based on the results from this study, it was determined that a ratio correction factor method provided the best fit for this FP XRF analytical device.
Occlusion-Based Object Transportation Around Obstacles With a Swarm of Miniature Robots
Authors: Queiroz Breno Cunha , MacRae Daniel 
Published: January 2024

Abstract

Swarm robotics utilises decentralised self-organising systems to form complex collective behaviours built from the bottom-up using individuals that have limited capabilities. Previous work has shown that simple occlusion-based strategies can be effective in using swam robotics for the task of transporting objects to a goal position. However, this strategy requires a clear line-of-sight between object and goal. In this paper, we extend this strategy by allowing robots to form sub-goals; enabling any member of the swarm to establish a wider range of visibility of the goal, ultimately forming a chain of sub-goals between the object and the goal position. We do so while maintaining the fully decentralised and communication-free nature of the original strategy. In three sets of simulated experiments, we demonstrate that our proposed approach allows a swarm of sufficient size to successfully transport objects around obstacles that occlude the goal from the starting position of the object, that this strategy is robust to different object shapes, and that our proposed changes do not reduce the performance of the strategy in environments where obstacles are not present.
In vitro chemopreventive activity and mechanism of action of p-coumaric acid in A431 cell line (Human epidermoid carcinoma cell)
Authors: Velusamy Pradeep , Muthusami Sridhar , Arumugam Ramakrishnan 
Published: January 2024

Abstract
Over the past few decades, skin cancer incidence has increased on a global scale. The most frequent type of cutaneous cancer is nonmelanoma skin cancer. One of the most significant and persistent secondary metabolites in plants are phenolic chemicals. Various fruits, vegetables, and grains contain p-coumaric acid. Although studies hint at its anticancer potential, more research, including clinical trials, is needed for a complete understanding. Consuming these plants within a balanced diet, rather than as isolated supplements, may offer broader health benefits. Due to its known biological and pharmacological characteristics, such as its anti-inflammatory, anti-bacterial, chemoprotective, and anticancer effects, p-coumaric acid has received a lot of interest. It is a promising anticancer agent with lower toxicity in human. Initially we performed MTT assay to understand the role p-coumaric acid in reducing mitochondrial activities of A431 cells, which revealed the IC50 value ± 52 µg/ml, which is similarly effective to the IC50 value of standard drug Imiquimod ± 52 µg/ml. To support this, we the performed mitochondrial membrane potential followed by ROS accumulation using DCF-DA. Then the cell cycle analysis was done to check the stage where p-coumaric acid is exerting inhibition/arrest. The ability to induce early/ late apoptosis was analyzed using flowcytometry. p-coumaric acid reduced the mitochondrial activity similar to the standard drug suggest the therapeutic usage of this compound. This is associated with increased ROS production and induction of cell cycle arrest and early apoptosis. p-coumaric acid is effective in reducing the survival and enhance apoptosis through ROS based mechanism.
Simulation of muscle activity in sports training based on optical coherence tomography technology
Authors: Yao Lingzi , Zhang Ye 
Published: January 2024

Abstract

The aim of this study is to explore the method of combining optical coherence tomography and EMG sensors to effectively analyze muscle activity patterns in sports. Optical coherence tomography is used to monitor the surface morphological changes of muscles in a non-invasive manner in real time, and electromyography sensors are combined to record the electrical activity signals of muscles. Through experiments on multiple athletes, a large number of optical coherence tomography and EMG data were collected to analyze muscle activity patterns in different sports. Optical coherence tomography provides precise information on muscle morphological changes, while EMG sensors provide signals of muscle electrical activity. Through the comprehensive analysis of these two kinds of data, more comprehensive and accurate results of muscle activity patterns can be obtained. This method helps to understand the performance of muscles during exercise, and provides scientific basis for exercise training and rehabilitation treatment.
Exploring the Potential of Terrestrial Isopoda, Porcellionides cingendus, for Assessing Environmental Sustainability
Authors: Salman Zainab Hamed ,   Ibrahim Mahdi Alsalman1
Published: January 2024

Abstract

Introduction: Environmental sustainability is crucial for maintaining diverse and productive biological systems. Terrestrial isopods, such as Porcellionides cingendus, are known for their environmentally friendly characteristics and adaptability. This study explores the potential of P. cingendus in improving environmental sustainability.
Methods: Samples of P. cingendus were collected from various locations and reared in controlled environments. Waste consumption efficiency was evaluated by measuring the consumption of various cellulosic wastes over 15 days. Statistical analysis was performed using One-Way ANOVA.
Results and Discussion: P. cingendus individuals exhibited varying consumption rates for different types of wastes. Wood sawdust recorded the highest consumption percentage (99.2%), followed by citrus leaves (81.9%), potato peels (70.4%), Cynodon dactylon (68.4%), and cardboard (34.1%). The consumption differences can be attributed to dietary preference, food source, and digestibility. Wood sawdust, with its cellulose content, was highly attractive to P. cingendus. Citrus leaves were preferred due to their chemical composition and smell. However, cardboard was the least preferred, possibly due to its chemical composition and lack of easy digestibility.
Conclusion: P. cingendus, particularly its preference for wood sawdust and citrus leaves, shows potential for efficiently consuming cellulosic wastes, indicating their ability to contribute to environmental cleaning and sustainability. Understanding the waste consumption efficiency of P. cingendus can aid in developing strategies for waste management and ecological preservation. Further research is warranted to explore their role as bioindicators for assessing environmental sustainability.
SWOT Analysis and Insights into the Health Research Authority Approval Process for COVID-19 Antimicrobial Stewardship Research in UK Secondary Care: Advocating Think Ethics
Authors: Elshenawy Rasha Abdelsalam , Umaru Nkiruka , Aslanpour Zoe 
Published: January 2024

Abstract
This article examines the Health Research Authority's (HRA) approval process, guided by the 'Think Ethics' ethos, for an antimicrobial stewardship (AMS) research project at an English NHS Foundation Trust amidst the COVID-19 pandemic. Employing a SWOT analysis to reflect critically on the process, the project encompassed a retrospective examination of patient records and a survey of healthcare staff, traversing the complexities of the Integrated Research Application System (IRAS). The HRA's streamlined procedures, involving meticulous reviews by the NHS Research Ethics Committee (REC) and regulatory checks, refined the approval process, precluding the need for multiple assessments across NHS bodies. Achieving HRA consent necessitated stringent adherence to confidentiality protocols and the submission of extensive documentation. Only upon securing all requisite regulatory approvals could the project proceed, highlighting the essentiality of proficient project management and strategic communication. The study's outcomes shed light on AMS practices, the shifts in antibiotic prescribing patterns, and the pandemic's influence on these dynamics. Crucially, the investigation emphasised the vital importance of robust AMS in managing antibiotic utilisation and in combating antimicrobial resistance. Reflection on this journey accentuated the value of public and patient engagement, the efficacy of participant recruitment materials, the merits of registering research internationally, and the importance of constructively addressing feedback. These lessons have substantially augmented the authors' research acumen, reinforcing the pivotal role of ethical deliberation and lucid communication in scholarly pursuits. This account presents an in-depth perspective of the HRA approval process, endorsing its integration in forthcoming AMS and antimicrobial resistance research, which remain significant global health issues.
Barium mobility in a geothermal environment, Yellowstone National Park
Authors: Zimmerman Jarred , Larson Peter B. 
Published: January 2024

Abstract
Ba-rich minerals are frequently observed in epithermal environments and include characteristic phases such as barite and alunite supergroup minerals. At Yellowstone, electron microprobe analysis shows that Ba in the unaltered third-cycle Tuff of Sulphur Creek is largely contained within sanidine phenocrysts (mean 1.60 wt% BaO) with lesser concentrations in plagioclase (mean 0.22 wt% BaO) and volcanic glass (mean 0.05 wt% BaO). Whole-rock XRD analyses of rocks hydrothermally altered by alkaline-chloride fluids at Ridge 7741 in Seven Mile Hole, Yellowstone National Park, show they are dominated by illite + quartz ± hydrothermal feldspar, primarily adularia. In this alteration zone, adularia is the principal phase that contains significant Ba (mean 0.43 wt% BaO). In shallower alteration, dominated by acid-sulfate assemblages, such as kaolinite + opaline silica ± alunite supergroup minerals (alunite, walthierite, huangite) ± barite, Ba is sequestered in the sulfate minerals. Alunite supergroup minerals (mean 1.12 wt% BaO) are more prevalent than barite and are largely found from the modern valley rim to about 60 m below the modern surface, especially around the South Fork of Sulphur Creek. However, nearly 80 m below the modern rim of the Grand Canyon of the Yellowstone River, in areas previously altered by alkaline-chloride fluids, adularia altered to alunite supergroup minerals may contain similar to slightly elevated Ba concentrations relative to the replaced grain. Barite is primarily found sporadically in altered rocks along the valley rim of the South Fork of Sulphur Creek, with rare occurrences along the rim of the Grand Canyon. Despite the hydrothermal alteration, whole-rock XRF and ICP-MS analyses show similar mean concentrations between unaltered (0.11 wt% BaO) and altered (0.09 wt% BaO) Tuff of Sulphur Creek samples. Hydrothermally altered rocks are important sources of Yellowstone low-δ18O rhyolites, like the Tuff of Sulphur Creek, which inherits their low δ18O signal from them. Cenozoic rhyolites throughout the North American Cordillera tend to exhibit high Ba concentrations, including the low-δ18O Yellowstone rhyolites. This work shows that hydrothermal alteration mobilizes Ba in volcanic units with minimal dispersion of Ba out of that unit. The genesis of similar silicic volcanic rocks with elevated Ba, relative to mean upper crustal concentrations, may be the result of partial melting of hydrothermally altered rock.