bluuebunny/crossref_metadata_2025_split huggingface dataset:
Development, validation, and accuracy of ORCHESTRA emotional exhaustion screening questionnaire among healthcare workers during COVID‐19 Pandemic
Authors: Gan Rick Kye , Arcos González Pedro , Fernandez‐Tardon Guillermo , Zerbo Alexandre , Calota Violeta Claudia , Klöslová Zuzana , Otelea Marina Ruxandra , Fabiánová Eleonóra , Rodriguez‐Suarez Marta‐Maria , Tardon Adonina 
Published: November 2023

AbstractBackgroundThe COVID‐19 pandemic has posed unprecedented challenges, particularly for healthcare workers (HCWs). The prolonged struggles exposed the HCWs to a variety of stressors, potentially leading to burnout. Emotional exhaustion is widely recognized as the core component of burnout. This research aims to conceptualize and develop an emotional exhaustion screening questionnaire through literature review, validation, and accuracy testing.MethodA literature review of questionnaires and extraction of items on emotional exhaustion were performed in June 2022. We proceed with the face validity of the items by experts. The items with good content validity ratio and index were selected and reworded to suit the context of HCWs working during the COVID‐19 pandemic. A pilot test of the questionnaire was done in the Central University Hospital of Asturias (HUCA) from October to December 2022 with a sample of 148 HCWs from the ORCHESTRA cohort to determine its reliability, convergent validity, and accuracy.ResultsOur literature review identified 15 validated questionnaires. After exclusion, 32 items were sent for content validation by experts, yielding five final items that proceeded with the pilot test. Resulting in a Cronbach's alpha‐coefficient of .83 for the scale and .78 for dichotomous responses, demonstrating good internal consistency and convergent validity. The result of our accuracy test yielded sensitivity (90.6%) and specificity (91.6%) for the OEEQ scale; and sensitivity (88.7%) and specificity (89.5%) for OEEQ dichotomous responses.ConclusionThis study developed and validated the ORCHESTRA Emotional Exhaustion Questionnaire, demonstrating the questionnaire's clarity, relevance, and comprehensibility in screening emotional exhaustion among HCWs.
T‐cell receptor sequencing reveals hepatocellular carcinoma immune characteristics according to Barcelona Clinic liver cancer stages within liver tissue and peripheral blood
Authors: Li Rui , Wang Junxiao , Li Xiubin , Liang Yining , Jiang Yiyun , Zhang Yuwei , Xu Pengfei , Deng Ling , Wang Zhe , Sun Tao , Wu Jian , Xie Hui , Wang Yijin 
Published: November 2023

AbstractAnalysis of T‐cell receptor (TCR) repertoires in different stages of hepatocellular carcinoma (HCC) might help to elucidate its pathogenesis and progression. This study aimed to investigate TCR profiles in liver biopsies and peripheral blood mononuclear cells (PBMCs) in different Barcelona Clinic liver cancer (BCLC) stages of HCC. Ten patients in early stage (BCLC_A), 10 patients in middle stage (BCLC_B), and 10 patients in late stage (BCLC_C) cancer were prospectively enrolled. The liver tumor tissues, adjacent tissues, and PBMCs of each patient were collected and examined by TCR β sequencing. Based on the ImMunoGeneTics (IMGT) database, we aligned the V, D, J, and C gene segments and identified the frequency of CDR3 sequences and amino acids sequence. Diversity of TCR in PBMCs was higher than in both tumor tissues and adjacent tissues, regardless of BCLC stage and postoperative recurrence. TCR clonality was increased in T cells from peripheral blood in advanced HCC, compared with the early and middle stages. No statistical differences were observed between different BCLC stages, either in tumors or adjacent tissues. TCR clonality revealed no significant difference between recurrent tumor and non‐recurrent tumor, therefore PBMCs was better to be representative of TCR characteristics in different stages of HCC compared to tumor tissues. Clonal expansion of T cells was associated with low risk of recurrence in HCC patients.
Balancing Rotation Minimizing Frames with Additional Objectives
Authors: Mossman C. , Bartels R. H. , Samavati F. F. 
Published: November 2023

AbstractWhen moving along 3D curves, one may require local coordinate frames for visited points, such as for animating virtual cameras, controlling robotic motion, or constructing sweep surfaces. Often, consecutive coordinate frames should be similar, avoiding sharp twists. Previous work achieved this goal by using various methods to approximate rotation minimizing frames (RMFs) with respect to a curve's tangent. In this work, we use Householder transformations to construct preliminary tangent‐aligned coordinate frames and then optimize these initial frames under the constraint that they remain tangent‐aligned. This optimization minimizes the weighted sum of squared distances between selected vectors within the new frames and fixed vectors outside them (such as the axes of previous frames). By selecting different vectors for this objective function, we reproduce existing RMF approximation methods and modify them to consider additional objectives beyond rotation minimization. We also provide some example computer graphics use cases for this new frame tracking.
Enhanced approach of multilabel learning for the Arabic aspect category detection of the hotel reviews
Authors: Ameur Asma , Hamdi Sana , Yahia Sadok Ben 
Published: November 2023

AbstractIn many fields, like aspect category detection (ACD) in aspect‐based sentiment analysis, it is necessary to label each instance with more than one label at the same time. This study tackles the multilabel classification problem in the ACD task for the Arabic language. For this purpose, we used Arabic hotel reviews from the SemEval‐2016 dataset, comprising 13,113 annotated tuples provided for training (10,509) and testing (2,604). To extract valuable information, we first propose specific data preprocessing. Then, we suggest using the dynamic weighted loss function and a data augmentation method to fix the problem with this dataset's imbalance. Using two possible approaches, we develop new ways to find different categories of things in a review sentence. The first is based on classifier chains using machine learning models. The second is based on transfer learning using pretrained AraBERT fine‐tuning for contextual representation. Our findings show that both approaches outperformed the related works for ACD on the Arabic SemEval‐2016. Moreover, we observed that AraBERT fine‐tuning performed much better and achieved a promising ‐score of .
Analysing the impact of paper grammage and pulp blend on electrophotographic printing systems
Authors: Sonmez Sinan , Engin Merve , Li Kecheng , Salam Abdus 
Published: November 2023

AbstractThe effect of fibre length and grammage on the electrophotographic digital printing process was investigated in this study. While integral optical density values on handsheets have shown no significant change, unprinted handsheets have shown an increasing change as short fibre content has increased. Because of structural changes in the paper surface, the measured results for print chroma, brightness, contrast, and delta gloss differed between paper groups. This research confirmed that these changes have nothing to do with grammage or fibre length content. Regardless of the fibre length ratios, significant increases in tone values of ink, were accompanied by a decrease in the grammage of the handsheets among the grammage groups provided. The specimen grammage affected the universal colour diagrams, but not the fibre length. The discrepancies in all of these printing outcomes were thought to be caused by the random distribution of fibres and the distances between them on the paper's surface.
Seizure course of PCDH19 clustering epilepsy in female children: A multicentre cohort study in China
Authors: Chen Yi , Liu Aijie , Zhang Xiaoli , Ma Xiuwei , Sun Dan , Tian Xiaojuan , Wu Wenjuan , Zeng Qi , Jiang Yuwu , Zhang Yuehua 
Published: November 2023

AbstractAimTo investigate the seizure course of PCDH19 clustering epilepsy (PCDH19‐CE) in a cohort of female children in China.MethodThis ambidirectional cohort study examined 113 female patients with PCDH19‐CE through multicentre collaboration. Prognostic factors for seizure freedom were evaluated by multivariate Cox regression analysis.ResultsThe median seizure course period from seizure onset was 6 years 6 months. Of 113 patients, 78% and 56% experienced seizure freedom for at least 1 year and at least 2 years respectively. In patients younger than 5 years (n = 30), 5 to 10 years (n = 52), and older than 10 years (n = 31), 57%, 81%, and 94% experienced at least 1 year of seizure freedom, and 32%, 52%, and 84% experienced at least 2 years of seizure freedom, respectively. However, 58% (65 out of 113) relapsed at least once after more than 1 year of seizure freedom without trigger exposure (40%) or because of common triggers, including fever (43%) and antiseizure medication (ASM) reduction (29%). There was an 84% risk of seizure relapse after ASM reduction attempts. The likelihood of seizure freedom decreased with early age at seizure onset and developmental delay.InterpretationPatients with PCDH19‐CE exhibit increasing seizure freedom with age, but there is a risk of relapse. ASM reduction in children younger than 10 years old requires caution. Patients with early seizure onset and developmental delay have a reduced chance of seizure freedom.What this paper adds

The seizure freedom rate in PCDH19 clustering epilepsy gradually increases with age.
The disease course is characterized by relapsing–remitting seizures.
Antiseizure medication reduction requires caution for patients younger than 10 years of age.
Patients with early seizure onset and developmental delay are less likely to achieve seizure freedom.
The real side of stock market exuberance: bubbles, output and productivity at the industry level
Authors: Queirós Francisco 
Published: November 2023

AbstractThere has been a growing interest in the theory of rational bubbles. Recent theories predict that bubbles are expansionary, but differ in the underlying mechanisms. This paper provides empirical evidence that helps us to assess different theories, and documents four main findings: stock market overvaluation is associated with (i) faster output and input growth, (ii) declining total factor productivity (TFP) growth, (iii) a greater contribution of labour and a declining contribution of TFP for output growth, (iv) an increase in the number of firms. Overall, these findings suggest that bubbly expansions are driven by increased factor accumulation (in particular labour), and not from higher productivity growth.
Theta oscillatory power decreases in humans are associated with spatial learning in a virtual water maze task
Authors: Thornberry Conor , Caffrey Michelle , Commins Sean 
Published: November 2023

AbstractTheta oscillations (4–8 Hz) in humans play a role in navigation processes, including spatial encoding, retrieval and sensorimotor integration. Increased theta power at frontal and parietal midline regions is known to contribute to successful navigation. However, the dynamics of cortical theta and its role in spatial learning are not fully understood. This study aimed to investigate theta oscillations via electroencephalogram (EEG) during spatial learning in a virtual water maze. Participants were separated into a learning group (n = 25) who learned the location of a hidden goal across 12 trials, or a time‐matched non‐learning group (n = 25) who were required to simply navigate the same arena, but without a goal. We compared all trials, at two phases of learning, the trial start and the goal approach. We also compared the first six trials with the last six trials within‐groups. The learning group showed reduced low‐frequency theta power at the frontal and parietal midline during the start phase and largely reduced theta combined with a short increase at both midlines during the goal‐approach phase. These patterns were not found in the non‐learning group, who instead displayed extensive increases in low‐frequency oscillations at both regions during the trial start and at the parietal midline during goal approach. Our results support the theory that theta plays a crucial role in spatial encoding during exploration, as opposed to sensorimotor integration. We suggest our findings provide evidence for a link between learning and a reduction of theta oscillations in humans.
How can white parents raise anti‐racist children? Introducing the routes to effective anti‐racist parenting (REAP) model
Authors: Belizaire Shequanna , Powers Margaret , Mekawi Yara 
Published: November 2023

AbstractIn response to highly publicized instances of overt racial injustice, there has been a recent resurgence of interest and commitment to identifying processes through which anti‐racist behaviors develop among White individuals. One particularly important context in which anti‐racist behaviors can develop is within families and as a result of childrearing. Theories of anti‐racism typically neglect the role of families and family science research typically neglects a focus on anti‐racist parenting outcomes. To further research and applied work on fostering anti‐racism within White families, this paper introduces a new integrative model called routes to effective anti‐racist parenting (REAP). The model draws on theories from various fields, including family science and social psychology, and uses a metaphor of nurturing a plant to explain the nuanced, multi‐faceted approaches to anti‐racist parenting. The model incorporates factors related to the “pot” (i.e., fundamental values and structure necessary to contain more specific anti‐racist skills and behaviors), “soil” (i.e., characteristics that define anti‐racist commitment), “seeds” (i.e., direct transmission of anti‐racism skills), and “environment” (i.e., influential external factors). Finally, we describe the intended benefits that can be reaped from this intentional approach to anti‐racist parenting. The REAP model contributes to the family science literature by providing an empirically grounded theoretical model describing the roles that parents can play in children's anti‐racist development.
Market power and systematic risk
Authors: Hollstein Fabian , Prokopczuk Marcel , Würsig Christoph Matthias 
Published: November 2023

AbstractWe examine the impact of product market competition on firms' systematic risk. Using a measure of total product market similarity, we document a strong negative relationship between market power and market betas. The effect more than triples in the most recent period of low competition. Anticompetitive mergers result in a significant reduction in market betas. Firms facing less competition seem to be partially insulated from systematic discount‐rate shocks. Lower equity costs therefore imply that market power is partly self‐perpetuating.
Variable influence of photosynthetic thermal acclimation on future carbon uptake in Australian wooded ecosystems under climate change
Authors: Bennett Alison C. , Knauer Jürgen , Bennett Lauren T. , Haverd Vanessa , Arndt Stefan K. 
Published: November 2023

AbstractClimate change will impact gross primary productivity (GPP), net primary productivity (NPP), and carbon storage in wooded ecosystems. The extent of change will be influenced by thermal acclimation of photosynthesis—the ability of plants to adjust net photosynthetic rates in response to growth temperatures—yet regional differences in acclimation effects among wooded ecosystems is currently unknown. We examined the effects of changing climate on 17 Australian wooded ecosystems with and without the effects of thermal acclimation of C3 photosynthesis. Ecosystems were drawn from five ecoregions (tropical savanna, tropical forest, Mediterranean woodlands, temperate woodlands, and temperate forests) that span Australia's climatic range. We used the CABLE‐POP land surface model adapted with thermal acclimation functions and forced with HadGEM2‐ES climate projections from RCP8.5. For each site and ecoregion we examined (a) effects of climate change on GPP, NPP, and live tree carbon storage; and (b) impacts of thermal acclimation of photosynthesis on simulated changes. Between the end of the historical (1976–2005) and projected (2070–2099) periods simulated annual carbon uptake increased in the majority of ecosystems by 26.1%–63.3% for GPP and 15%–61.5% for NPP. Thermal acclimation of photosynthesis further increased GPP and NPP in tropical savannas by 27.2% and 22.4% and by 11% and 10.1% in tropical forests with positive effects concentrated in the wet season (tropical savannas) and the warmer months (tropical forests). We predicted minimal effects of thermal acclimation of photosynthesis on GPP, NPP, and carbon storage in Mediterranean woodlands, temperate woodlands, and temperate forests. Overall, positive effects were strongly enhanced by increasing CO2 concentrations under RCP8.5. We conclude that the direct effects of climate change will enhance carbon uptake and storage in Australian wooded ecosystems (likely due to CO2 enrichment) and that benefits of thermal acclimation of photosynthesis will be restricted to tropical ecoregions.
Effect of conventional hemodialysis on the apixaban plasma concentration
Authors: Poel Tim , de Rouw Nikki , Péquériaux Nathalie C. V. , van de Kerkhof Daan , Windsant Annemieke M.A. Vermeulen , van Marum Rob J. , Kerckhoffs Angele P. M. 
Published: November 2023

AbstractPurposeApixaban is a factor Xa inhibitor used in patients undergoing hemodialysis treatment. The objective of this study is to investigate the effect of hemodialysis on apixaban plasma concentrations.MethodsThis observational study is on patients treated with apixaban 2.5 mg twice daily on conventional hemodialysis with standard low‐molecular‐weight heparin (LMWH) anticoagulation (nadroparin 3800–7600 IU). Plasma blood samples were collected before starting dialysis (t1), 2 h after starting dialysis (t2), and directly after dialysis (t3). Apixaban concentration was measured before and after dialysis. Anti‐Xa activity was measured for all three samples.ResultsA significant difference was observed between the apixaban concentration before and after dialysis (mean before dialysis 141.03 ng/mL; mean after dialysis 102.71 ng/mL; p = 0.003). Nonetheless, both apixaban plasma concentrations and anti‐Xa levels remained within the reference range. Anti‐Xa levels had a strong correlation with the apixaban concentrations (r = 0.935, p = 0.000). Thus, anti‐Xa activity might be used as a surrogate for apixaban plasma concentration.ConclusionThere seems to be no need for dose adjustments of apixaban; co‐administration of LMWH next to apixaban might also be unnecessary.
Patriarchal bargains in short‐term women's migration from Bangladesh
Authors: Wu Joyce , Kilby Patrick , Rashid Syeda Rozana , Sarker Noor Mohammad 
Published: November 2023

AbstractThis paper looks at the migration of women from Bangladesh to the Middle East as short‐term migrants, mainly for work in the domestic care sector as domestic workers, housekeepers, nannies, cooks, etc. This group accounts for about 15 per cent of the total short‐term migration cohort. They face particular challenges around not only the precarity of their employment but also in navigating a series of patriarchal norms in both Bangladesh and the destination countries in the Middle East. The paper will build on the work of Deniz Kandiyoti and her seminal work on patriarchal bargains. This paper will explore the challenges women face in migrating to the Middle East: in their decision to migrate, their experiences abroad, and on return and reintegration into Bangladesh society and their home life, and how these are determined by a series of patriarchal bargains both in Bangladesh and the destination country.
Intratracheal administration of cross‐linked water‐soluble acrylic acid polymer is associated with inducible bronchi‐related lymphoid tissue formation and allergic inflammation
Authors: Kido Takamasa , Sugaya Chiemi , Hano Hiroshi , Yanagisawa Hiroyuki , Suka Machi 
Published: November 2023

AbstractIn a Japanese chemical factory, lung diseases such as pneumoconiosis have been reported among workers handling cross‐linked water‐soluble acrylic acid polymers (CWAAP). Our previous study reported that a single intratracheal administration of CWAAP induces acute inflammation and fibrosis. In this study, we investigated the effects of multiple intratracheal administrations of CWAAP on inflammatory responses and pulmonary fibrosis along with inducible bronchus‐associated lymphoid tissues (iBALT) formation, which is involved in allergic inflammation. Male F344 rats (190–200 g) received single or multiple intratracheal administrations of phosphate‐buffered saline (PBS) or CWAAP. To assess inflammatory responses and pulmonary fibrosis, immunohistochemical and histological staining was performed. CD68, CD163, CD169, TGF‐β, and collagen I positive cells/areas in the lungs of the CWAAP‐group rats were significantly increased than those in the PBS group. Furthermore, the number of iBALT structures, CD4 + T cells, along with CD19, PAX5, IL‐4, GATA‐3, T‐bet, and IgE‐positive cells in the terminal bronchioles and blood vessels of the lungs were significantly increased in the CWAAP group. Moreover, pulmonary fibrosis, iBALT formation, and levels of specific IgG were significantly increased in rats who received multiple intratracheal administrations of CWAAP compared to those with single intratracheal administration. Multiple intratracheal administrations of CWAAP potentiated the classical fibrotic pathway (M2 macrophage‐TGF‐β‐collagen I) more potently than single intratracheal administration. Furthermore, it was possible that iBALT was formed around terminal bronchioles and blood vessels and the number of immune cells was increased, resulting in enhanced allergic inflammation and pulmonary fibrosis.