bluuebunny/crossref_metadata_2025_split huggingface dataset:
APPLYING USER-CENTERED DESIGN FOR MOBILE APPLICATIONS INTERFACE DESIGN
Authors: Farasalsabila Fidya , Lestari Verra Budhi , Nugroho Jangkung Tri , Pramudyantoro Arvi , Utami Ema 
Published: January 2024

Abstract: The Healthy Food Supplier App, which introduces groundbreaking innovations to increase public access to and delivery of healthy food, has emerged as a new phenomenon in the food sector. This research intends to examine and describe how the use of healthy food suppliers contributes to improving public health by making healthy food accessible to obtain and deliver it quickly. The development of mobile applications with the aim of providing healthy food and ingredients for the community is the subject of this research. The aim of this app is to provide original responses to issues related to raising awareness of quality of life and the value of nutritious food in everyday life. The User Centered Design (UCD) method needs to be applied to categorize various user information needs and package them into a mobile application design model. The results of the application design showed that the interface design for the pioneer food and health food raw material application was successfully created using the implementation of the UCD method with a number of revisions that have been updated since the evaluation as one of the feature developments in the application. The food recording feature and personalized recommendations implemented in this mobile application provide users with awareness and guidance in adopting healthier eating patterns. Keywords: Design Interface; Mobile Applications; Requirements Engineering; User-Centered Design Abstrak: Aplikasi Pemasok Makanan Sehat yang memperkenalkan inovasi terobosan untuk meningkatkan akses publik ke dan pengiriman makanan sehat, telah muncul sebagai fenomena baru di sektor makanan. Penelitian ini bermaksud untuk mengkaji dan mendeskripsikan bagaimana penggunaan pemasok makanan sehat berkontribusi dalam peningkatan kesehatan masyarakat dengan membuat makanan sehat dapat diakses untuk mendapatkan dan mengantarkannya dengan cepat. Pengembangan aplikasi mobile dengan tujuan menyediakan makanan dan bahan makanan sehat bagi masyarakat menjadi pokok bahasan penelitian ini. Tujuan dari aplikasi ini adalah untuk memberikan tanggapan orisinal terhadap masalah yang terkait dengan peningkatan kesadaran kualitas hidup dan nilai makanan bergizi dalam kehidupan sehari-hari. Metode User Centered Design (UCD) perlu diterapkan untuk mengkategorikan berbagai kebutuhan informasi pengguna dan mengemasnya ke dalam model desain aplikasi mobile. Hasil perancangan aplikasi didapatkan bahwa desain antarmuka aplikasi pelopor makanan dan bahan baku makanan kesehatan berhasil dibuat dengan menggunakan implementasi metode UCD dengan sejumlah revisi yang sudah diperbarui sejak evaluasi sebagai salah satu pengembangan fitur pada aplikasi. Fitur pencatatan makanan dan rekomendasi personal yang diterapkan pada aplikasi mobile ini memberikan pengguna kesadaran dan panduan dalam mengadopsi pola makan yang lebih sehat. Kata Kunci: Design Interface; Mobile Applications; Requirements Engineering; User-Centered Design
E-SCM (SUPPLY CHAIN MANAGEMENT) MANAGEMENT OF EDUCATIONAL OIL SUPPLY AT UD. HASTIN
Authors: Ningsih Ade Irma Suriya , Nurwati Nurwati , Rohminatin Rohminatin 
Published: January 2024

Abstract: Today's highly competitive trade competition requires business owners to be able to create products and services that are cheaper, better and faster so that they can satisfy consumers. UD. Hastin is a distributor of cooking oil located on Jl. Lt. Gen. Suprapto No. 16 Tanjung Balai – Asahan, North Sumatra. Cooking oil is a very high demand household product. Therefore, it is necessary to have good stock control so that there is no shortage or excess of stock. The problems faced by UD. Hastin currently has limitations in controlling inventory because it is still done manually, which causes slow and inefficient performance. The purpose of this research is to design a Supply Chain Management at UD. Hastin uses the PHP programming language and MySQL database by implementing a web-based system that will make it easier to manage oil supplies. The method used in this research is a qualitative method with literature and field studies. The conclusion, the E-SCM was built at UD. Hastin can avoid shortages and excess stock due to better management, smoother communication with suppliers, and information on UD. Hastin's stock items can be known in real-time. The product resulting from this research is the Stock Management Information System at UD. Hastin. Keywords: edible oil; E-SCM; suppliers; supply Abstrak: Persaingan dagang yang sangat kompetitif saat ini menuntut pemilik usaha untuk dapat menciptakan produk dan jasa yang murah, lebih baik dan lebih cepat sehingga bisa memuaskan konsumen. UD. Hastin merupakan distributor minyak makan yang berlokasi di Jl. Letjend. Suprapto No. 16 Tanjung Balai – Asahan, Sumatera Utara. Minyak makan merupakan produk rumah tangga yang sangat tinggi permintaanya. Oleh karenanya perlu pengendalian stok yang baik agar tidak kekurangan dan atau kelebihan stok. Permasalahan yang dihadapi oleh UD. Hastin saat ini adalah keterbatasan dalam mengontrol stok persediaan karena masih dilakukan secara manual, yang menyebabkan kinerja yang lambat dan kurang efisien. Tujuan dari penelitian untuk merancang Supply Chain Management pada UD. Hastin menggunakan bahasa pemrograman PHP dan database MySQL dengan menerapkan sistem berbasis web yang akan mempermudah dalam pengelolaan persediaan minyak. Metode yang digunakan dalam penelitian ini ialah metode kualitatif dengan studi pustaka dan studi lapangan. Kesimpulannya E-SCM yang dibangun di UD.Hastin mampu menggindari kekurangan dan kelebihan stok karena pengelolaanya yang lebih baik, komunikasi dengan supplier lebih lancer dan informasi stok barang UD.Hastin bisa diketahui secara real time. Dan Produk yang dihasilkan adalah Sistem Informasi Pengelolaan Stok Barang pada UD. Hastin. Kata kunci: E-SCM; minyak makan; persediaan; supplier
ORGANIZAÇÕES HÍBRIDAS NA CONCESSÃO DE AEROPORTOS BRASILEIROS: UMA ANÁLISE À LUZ DO INSTITUCIONALISMO
Authors: Bambirra de Assis Lílian , Pessoa Araújo Uajará , de Almeida Matos Bruno , Daniela de Oliveira Fonseca Jaqueline 
Published: January 2024

Para administrar alguns aeroportos brasileiros, optou-se pelas Sociedades de Propósito Específico, forma de organização híbrida que reúne empresas de diferentes setores para gerenciar os terminais, junto à INFRAERO, impondo a participação de uma empresa pública no ajuste. Esse trabalho analisou o processo de formulação e funcionamento da concessão dos terminais e os contratos oriundos destas licitações, considerando os pressupostos da Teoria Institucional. Foi realizada uma pesquisa documental envolvendo os documentos de concessão dos aeroportos, reportagens sobre o tema e sites das organizações envolvidas. Considerando que se trata de um ajuste firmado por meio de contrato formal, encontram-se pontos oriundos dessa relação que se enquadram nas abordagens da Teoria Institucional, sobretudo, os riscos e oportunismos da perspectiva econômica e práticas isomórficas de desempenho, da vertente sociológica. Observa-se, ainda, o reforço da instituição da modernização e eficiência da administração pública, advinda do setor privado.
Palavras-Chave: Teoria Institucional. Organizações híbridas. Aeroportos brasileiros. Sociedades de propósito específico. Concessões.

Abstract: For management some Brazilian airports, the Special Purpose Companies were chosen, a form of hybrid organization that units companies from different sectors to manage the terminals, beside to INFRAERO, imposing the participation of a public company in the adjustment. This paper analyzed the process of elaboration and operation of the concession of the terminals and contracts related, considering the Institutional Theory assumptions. Documentary research was conducted involving the documents of concession, reports on the theme and websites of the organizations. Considering that this is an agreement signed by means of a contract, there are points from this relationship that fall within the approaches of the Institutional Theory, above all, the risks and opportunism of the economic perspective and isomorphic practices of performance, of the sociological aspect. It is also observed the intensification of the institution of modernization and efficiency of public administration.
Keywords: Institutional theory. Hybrid organizations. Brazilian airports. Special purpose companies. Concessions.
Development of Ocular Inserts Based on Import Substituted Poloxamer Emuxol 268
Authors: Bakhrushina E. O. , Turaeva A. R. , Zhalyalova D. R. , Klimov D. A. , Demina N. B. , Krasnuk I. I. 
Published: January 2024

Introduction. Emuxol-268 (JSC "NIOPIK", Russia) is a block copolymer produced in Russia with similar in physicochemical and biological properties to poloxamer Kolliphor® P 188 (Pluronic F68) manufactured by BASF, USA. However, a comparison of the properties of natural polymers to assess the prospects of their dosage forms has not been carried out before.Aim. The aim of the study was to demonstrate the interchangeability of auxiliary components using the example of the development of an ophthalmic drug insert by comparing the results of testing the dosage form in terms of such quality parameters as elasticity, thickness, mucoadhesion, pH, biodegradation time and irritation test (hen’s egg-chorioallantoic membrane test, HET-CAM test).Materials and methods. Poloxamers Emuxol 268 (JSC "NIOPIK", Russia) and Kolliphor® P 188 (BASF, Germany), hydroxyethyl cellulose (Natrosol™ 250 HHX, Ashland Global Holdings Inc., USA), and glycerol (LLC "Tulskaya Pharmfabrika", Russia) were used in the experiment. Elasticity, thickness, mucoadhesion, pH, biodegradation time, HET-CAM test were used as screening methods to identify the benefits of the composition.Results and discussion. Experiment results proved that the use of a domestic analogue makes it possible to create an ocular insert with improved quality parameters. The difference in the elasticity index of the inserts differs by 1.3 times, mucoadhesion – 1.7 times, biodegradation time – 2.5 times. In this connection, it can be assumed that an insert based on a domestic polymer contributes to an increase in the time of contact with the eye surface, thereby providing a prolonged effect of the drug and improving its bioavailability. The results obtained may be due to the difference in the average molecular weight of the hydrophobic polyoxypropylene part, which is 2600 Da for Emuxol 268 and 1800 Da for Kolliphor 188. The HET-CAM method showed the same results of the two compositions, both compositions do not have an irritating effect.Conclusion. Summing up, the only analogue of Kolliphor® P 188 available on the Russian pharmaceutical market – Emuxol-268 of JSC NIOPIK is a promising substance for replacement in the development of ophthalmic dosage forms. Despite the differences in physicochemical properties of the domestic block copolymer in comparison with the replaced poloxamer 188, its introduction into placebo inserts gave improved results in terms of quality indicators, which was revealed during a biopharmaceutical analysis.
Detection of Immunochemical Reactions Using Piezoquartz Immunosensor. Regeneration of the Electrode Bio-layer (Review)
Authors: Gogina S. S. , Smirnova E. A. , Stanishevskii Ya. M. , Stoinova A. M. 
Published: January 2024

Introduction. One of the most promising types of immunosensors is quartz crystal microbalance immunosensors (QCM immunosensors). Single-use biosensors are financially demanding, thus rendering the regeneration of the biosensor surface a pertinent issue for QCM immunosensors. Regeneration plays a pivotal role in sustaining the functionality of the sensor and enabling its reusability. In this article, "immunosensor" and "immunobiosensor" are interchangeable terms and are used to denote the same type of biosensors operating based on immunochemical interactions between antigens and antibodies.Text. This review discusses the features, operational principles, and applications of QCM immunosensors. Particular attention is directed toward the challenge of regenerating the biosensor surface as a key aspect ensuring their effective operation and the potential for multiple uses. Various regeneration methods and their advantages are examined. The reactivation of the biosensing layer on the QCM electrode secures its stability and functionality over extended periods, which is especially valuable in clinical and scientific research. The possibility of reusing the biosensor reduces material costs and waste production, aligning with ecological and economic concerns. Furthermore, the ability to analyze different analytes on the same surface fosters versatility in multiparametric investigations. It is essential to emphasize that the removal of residual analytes and the biosensor's regeneration process enhance reliability, selectivity, heightened sensitivity, and the potential for reproducible measurements.Conclusion. An analysis of scientific literature underscores the pivotal role of biosensor regeneration in maintaining functionality and reusability. The strength of the antigen-antibody interaction determines the conditions, which must be tailored individually for each antigen-antibody pair. The review thoroughly explores three primary approaches to the regeneration of piezoelectric transducers, including the use of a chemical method, oxygen plasma-based techniques, and the application of Piranha solution.
Comparative Study of Free Amino Acid Profiles in Underground Organs of Several Species of the Genus Rumex During Different Phases of the Vegetation Cycle
Authors: Poluyanov A. M. , Matvienko U. A. , Sokolova A. Yu. , Savelyeva A. E. , Durnova N. A. , Bobkova N. V. 
Published: January 2024

Introduction. Amino acids (AA), the primary metabolites in plants, play a crucial role in various physiological processes, including the synthesis of phenolic compounds. Drug products and dietary supplements made from medicinal plants can become a rich source of both nonessential and essential amino acids. High levels of free amino acids found in herbal raw material often indicate the presence of biotic and abiotic stress in the plants. Therefore, understanding the dynamics of bioactive compound accumulation in plants throughout their phenological phases of development is critical to optimizing their potential health benefits.Aim. To compare qualitative composition and dynamics of AA accumulation in the underground organs of four representatives of the Rumex genus: R. confertus, R. crispus L., R. obtusifolius L., R. aquaticus L. of three different vegetative phases.Materials and methods. Water extracts from underground organs of the studied plants were analyzed using two different methods for qualitative and quantitative analysis. Extracts were applied to the chromatographic plates TLS Silica gel 60 F254 (Merk, Germany) 20 × 20 cm with a micro-syringe (LLC "Tsvet", Russia). After elution, the plates were treated with a 2 % ninhydrin solution. Quantitative analysis was carried out using the SF-2000 spectrophotometer (LLC "OKB Spectr", Russia).Results and discussion. The amino acid profile of the underground organs of R. confertus, R. crispus L., R. obtusifolius L., R. aquaticus L. during three vegetative phases was determined using the TLC method; the quantitative analysis performed using spectrophotometry.Conclusion. The most diverse amino acid (AA) profiles were found in the withering phase in all Rumex species, with up to 9 amino adsorption zones. In contrast, the least diverse AA profiles were observed in the flowering phase, ranging from 2 to 4 adsorption zones. The quantitative content of AA was lowest in the flowering phase, increased during the regrowth phase, and peaked in the withering phase. However, R. crispus L. showed an unusual pattern, with the highest quantitative content of AA detected in the regrowth phase.
The COVID-19 Epidemic as a Lever for the Renewal of Higher Education in the State of Israel
Authors: Cohen Shirly Ester , Sabag Ziva 
Published: January 2024

The State of Israel is currently considered a “start-up nation” that stands out in the proportion of educated people with a tertiary education (which currently stands at 50.1% compared to OECD countries at 38.6%), which constitutes an essential and central growth engine in the entire Israeli economy. two years ago, on 12/03/2020, As a result of the COVID-19 epidemic, the higher education system moved to a state of online emergency teaching in which educational and organizational processes were accelerated.
The purpose of this research is to discuss how the higher education system in Israel is dealing with the systemic changes that have been made over the past three years While referring to the role of the institutions to equip the graduates with the skills and characteristics necessary to strengthen the status of Israel’s “start-up nation”.
Gastrite e duodenite linfoplasmocíticas em cão: Relato de caso
Authors: Oliveira Caroline Rodrigues de , Volkweis Fabiana Sperb 
Published: January 2024

A doença inflamatória intestinal (DII) ou enteropatia inflamatória crônica em cães, é caracterizada por alterações inflamatórias crônicas do trato grastrointestinal, das quais possuem etiologia multifatorial e difícil diagnóstico. Entre as principais causas da DII estão a predisposição genética, disbiose, aumento da permeabilidade intestinal e fatores ambientais. Os sinais clínicos são inespecíficos, recorrentes ou persistentes, incluindo vômitos, diarreia, perda de peso e alteração do apetite, por um período superior a três semanas. O diagnóstico costuma ser feito a partir da exclusão de patologias diferenciais, através da anamnese e exames complementares. O tratamento é baseado na modificação da dieta, utilização de corticosteroides, imunossupressores, antibióticos, além de terapia de suporte com nutracêuticos e tratamentos alternativos. O prognóstico da doença é variável, a depender do tipo de enteropatia e sua severidade. Este estudo tem como objetivo relatar o processo de investigação clínica, acerca de um caso de gastrite hiperplásica e duodenite erosiva linfoplasmocíticas, apresentadas em um canino, macho, da raça Dachshund, de 7 anos, com histórico de diarreia crônica e vômitos biliosos esporádicos. A metodologia utilizada no presente artigo refere-se a um estudo observacional descritivo do tipo relato de caso. Dessa forma, expõe a investigação dos sinais clínicos, onde foram descartados diagnósticos diferenciais, sugerindo-se o diagnóstico, tratamento e prognóstico pertinentes para doença inflamatória intestinal. Até o momento, o animal permanece em tratamento e estabilizado.
Pengembangan Kawasan Berkarakter Urban Crack melalui Desain Pasar Tematik Berbasis Material Daur Ulang Kain di Ciakar, Tangerang
Authors: Wicaksono Emanuel Agung , Winnerdy Fernisia Richtia , Prayangga Angeline Sie 
Published: January 2024

Ciakar Village, located in Panongan sub-district, Tangerang Regency, Banten, experienced significant physical spatial development, namely land use change from agriculture to settlements. The phenomenon of urban crack emerged as a result of this development. Urban crack refers to a narrow area hidden behind a prosperous and once thriving area that no longer has energy and is intrinsically characterized by emptiness. Urban crack in Ciakar village is triggered by the gated community system in the housing clusters that flank the site, resulting in street space that tends to be unmanaged and neglected which is then utilized wildly for plantations, kiosks, garbage disposal areas because there is no control and supervision.
The Ciakar village government plans to activate and revitalize this area by injecting a thematic market function that is expected to improve the quality of urban space as well as become an economic space for informal communities in improving their standard of living. The concept of a thematic market that combines culinary areas, shopping tours, educational tours, community activities by promoting local wisdom in the form of a park that can be built at an affordable cost. PKM UPH team contributed to propose the design of this thematic market. In the design process, there are two scales of design. Micro-scale design produces affordable building materials by utilizing fabric-based recycled materials with experimental methods to produce prototypes. The macro-scale design produces architectural design ideas for the thematic market by considering the existing context. In this study, the team used qualitative research methods. Data were collected from activities: field observations and Forum Group Discussions (FGDs) involving Ciakar Village government officials and community members. The design method used was a participatory design approach.
Species-specific roles of the Notch ligands, receptors, and targets orchestrating the signaling landscape of the segmentation clock
Authors: Ramesh Pranav S. , Chu Li-Fang 
Published: January 2024

Somitogenesis is a hallmark feature of all vertebrates and some invertebrate species that involves the periodic formation of block-like structures called somites. Somites are transient embryonic segments that eventually establish the entire vertebral column. A highly conserved molecular oscillator called the segmentation clock underlies this periodic event and the pace of this clock regulates the pace of somite formation. Although conserved signaling pathways govern the clock in most vertebrates, the mechanisms underlying the species-specific divergence in various clock characteristics remain elusive. For example, the segmentation clock in classical model species such as zebrafish, chick, and mouse embryos tick with a periodicity of ∼30, ∼90, and ∼120 min respectively. This enables them to form the species-specific number of vertebrae during their overall timespan of somitogenesis. Here, we perform a systematic review of the species-specific features of the segmentation clock with a keen focus on mouse embryos. We perform this review using three different perspectives: Notch-responsive clock genes, ligand-receptor dynamics, and synchronization between neighboring oscillators. We further review reports that use non-classical model organisms and in vitro model systems that complement our current understanding of the segmentation clock. Our review highlights the importance of comparative developmental biology to further our understanding of this essential developmental process.
Differential effects of location and object overlap on new learning
Authors: Chaloupka Benjamin , Zeithamova Dagmar 
Published: January 2024

IntroductionOverlap with prior experience facilitates learning in some cases while hindering it in others. As facilitation and interference are typically studied in separate lines of research, using distinct paradigms, it is unclear what key factors drive the opposing behavioral outcomes.MethodsIn two experiments, we tested whether both effects can be observed within a single task, depending on what overlaps between experiences. Participants completed a novel task in which they learned a grid of object-location associations, followed by a second grid that overlapped with the first in locations and/or objects. We hypothesized that overlap of locations would serve as a spatial schema, facilitating new learning, while overlap of objects would create interference.ResultsIn line with our hypothesis, we found that location overlap facilitated learning of the second grid, while object overlap hindered learning of the second grid. We replicated these findings in a second experiment, additionally showing that both effects remain largely stable across two distinct grid shapes.DiscussionThese results demonstrate that the effect of overlap can be manipulated within a single task, pinpointing one factor that determines the direction of the effect and highlighting the differential roles of “what” and “where” in the organization of memory.