bluuebunny/crossref_metadata_2025_split huggingface dataset:
Nothing is impossible: a 110-year-old patient recovered smoothly after partial hepatectomy — a case report
Authors: Yi Xiao-Kang , Wang An-Kang , Yao Jing , Li Qiu-Xi 
Published: October 2023

Abstract
Background
The population of centenarians is increasing, and the medical demand of it will also increase. Surgery for centenarians is a considerable challenge for patients and doctors.
Case Presentation
A 110 year-old woman presented with a history of epigastric pain for 1 month. The abdominal contrast-enhanced CT showed a visible lump with unclear boundaries in the left lateral lobe of liver, about 6*7cm in size. She underwent the open partial hepatectomy and lymph node dissection within 2 hours and 11 minutes. Histopathological examination revealed Intrahepatic Cholangiocarcinoma, stage T2aN0M0. No tumor recurrence was found during the 11 months follow-up.
Conclusion
To our best knowledge, this woman should be the first case in the world to have had a partial hepatectomy in centenarians. The patient recovered smoothly after surgery. We all know that the main challenge faced by centenarians is the vulnerable bodies are lack of physiological reserve but not the surgery itself. For centenarians, preoperative evaluation, medical optimization, anesthesia management, expeditious surgery, coordinated multidisciplinary and careful perioperative nursing are paramount.
Coupled Scheme for Linear and Hamilton-Jacobi Equations: Theoretical and Numerical Aspects
Authors: Sahu Smita 
Published: October 2023

Abstract
We present a comprehensive analysis of the coupled scheme introduced in [Springer Proceedings in Mathematics \& Statistics, vol 237. Springer, Cham 2018 \cite{S2018}] for linear and Hamilton-Jacobi equations. This method merges two distinct schemes, each tailored to handle specific solution characteristics. It offers a versatile framework for coupling various schemes, enabling the integration of accurate methods for smooth solutions and the treatment of discontinuities and gradient jumps. In \cite{S2018}, the emphasis was on coupling an anti-dissipative scheme designed for discontinuous solutions with a semi-Lagrangian scheme developed for smooth solutions. In this paper, we rigorously establish the essential properties of the resulting coupled scheme, especially in the linear case. To illustrate the effectiveness of this coupled approach, we present a series of one-dimensional examples.
Serum cell-free DNA released from postmortem subjects
Authors: Fujihara Junko , Nishimoto Naoki , Kimura-Kataoka Kaori , Takeshita Haruo , Takinami Yoshikazu 
Published: October 2023

Abstract

Background Cell-free DNA (cfDNA) is DNA released from dying cells into the serum.
In this study, the origin and mechanism of cell-free DNA (cfDNA) release in postmortem subjects were evaluated by measuring the levels of M30, M65, cyclophilin A (CyPA), and myeloperoxidase (MPO) to evaluate the origin of cfDNA.
Methods Serum (n = 54) was sampled from postmortem autopsied Japanese subjects.cfDNA was extracted and M30, M65, CyPA, and MPO in serum were assayed by enzyme-linked immunosorbent assay.
Results Significantly higher serum levels of M30, M65, and MPO were observed in postmortem subjects than in living subjects. Although the difference was smaller, CyPA was also significantly higher in postmortem subjects than in living subjects. In addition, serum M30 and MPO levels were significantly correlated with cfDNA concentrations in postmortem subjects. Moreover, M30 levels slightly increased according to the postmortem interval, while M65 levels were slightly higher with a 1.5-day postmortem interval.
ConclusionElevated levels of cfDNA in postmortem subjects are released by apoptosis and neutrophils via NETosis, that apoptosis is highly induced according to the postmortem interval, and that necrosis and NETosis are continually induced.
Bobfinchite, Na[(UO2)8O3(OH)11]·10H2O, a new Na-bearing member of the schoepite family
Authors: Olds Travis A. , Plášil Jakub , Kampf Anthony R. , Burns Peter C. , Marty Joe , McCloy John S. 
Published: October 2023

Abstract
The new mineral bobfinchite (IMA2020-082), Na[(UO2)8O3(OH)11]·10H2O, was found in the Burro mine, Slick Rock district, San Miguel County, Colorado, U.S.A., where it occurs as an oxidation product of uraninite on asphaltite matrix in intimate association with gypsum, natrozippeite, metaschoepite, and uranopilite. Bobfinchite crystals are transparent to translucent, yellow, lozenge-shaped disks up to 0.3 mm wide. Crystals are flattened on [100] and exhibit the forms {100}, {011}, {021}, {021}, and {011}. Bobfinchite has a pale-yellow streak and emits very dim yellow fluorescence under 365 nm ultraviolet illumination. The crystals are brittle with very good {100} cleavage and irregular, stepped fracture. The Mohs hardness is ca. 2 based on scratch tests. The calculated density is 5.044 g/cm3 based on the empirical formula and 5.036 g/cm3 for the ideal formula. Bobfinchite is optically biaxial (–), with α = 1.690(5), β = 1.7205(5), and γ = 1.730(5) (white light). The measured 2V, estimated from the interference figure, is 55(5)° and the calculated value is 59.1°. Dispersion is moderate, r &gt; v; orientation: X = a, Y = b, Z = c; pleochroism: X nearly colorless, Y yellow, Z yellow; X &lt; Y ≈Z. Electron microprobe analysis provided the empirical formula (Na0.99Pb0.02)[(UO2)7.99O3(OH)11]·10H2O. The five strongest X-ray powder diffraction lines are [dobs in Å(I)(hkl)]: 7.34(100)(200), 3.59(50)(024), 3.23(60)(224), 3.18(36)(240), and 2.01(23)(624,551,208,640,346). Bobfinchite is orthorhombic, Pbcn, a = 14.6249(9), b = 14.0389(10), c = 16.6923(10) Å, V = 3427.2(4) Å3, and Z = 4. The structure of bobfinchite (R1 = 0.0330 for 3770 I &gt; 4σI) is built from uranyl oxide-hydroxide sheets that adopt the fourmarierite topology, with interlayer Na+ and H2O groups. Both the sheet and interlayer topology mimic those observed in natural and synthetic Na-metaschoepites studied previously, and as seen in other uranyl oxide hydrate minerals, charge balance is achieved at specific sites in the sheet through the substitution O2– ↔ (OH)–.
Valorization of lignocellulosic solid waste obtained from essential oil industry for bio-oil production and dye removal
Authors: Modak Sourodipto , Katiyar Priyanka , Yadav Sanjeev , Hans Annapurna 
Published: October 2023

Abstract

This research underscores the potential of utilizing carrot seed waste and its derived biochar as effective solutions for waste management and wastewater treatment applications. This waste is thoroughly characterized for its chemical, thermal, and morphological properties. It is found to be rich in carbon and cellulose, proved suitable for pyrolysis, yielding 25% biochar and 45% bio-oil, with the latter containing carboxylic acids and hydrocarbons. Biochar, characterized by a high surface area of around 300 m2/g, micro- and mesopores, and the presence of metal oxides, demonstrated outstanding adsorption properties. Biochar shows superior performance compared to raw carrot seed waste, mainly in the context of methylene blue dye removal, obtaining an impressive removal efficiency of 99%. Subsequently, optimization of pH, adsorbent dosage, dye concentration, and reaction temperature is carried out using biochar as the adsorbent to maximize dye removal and adsorption capacity, whereas adsorption kinetics follows pseudo-first-order kinetics.
Application of blockchain technology in water management and new energy economic development
Authors: Zhang Jun 
Published: October 2023

Abstract
With the continuous development of the sustainability concept, the status and role of scientific management of resources and healthy economic development in social construction are becoming more and more prominent, and the problems and contradictions of water management and new energy economic development are also emerging. To enhance the scientificity of water management and promote the healthy development of a new energy economy, this paper discusses the application of blockchain technology in water management and the development of a new energy economy on the basis of analyzing its current situation. To verify the effectiveness of blockchain technology, this paper took S City as the research object, applied the decision model based on blockchain technology to water management and new energy economic development optimization decisions, and made an empirical analysis from three aspects: water management effect, new energy economic development level, and overall effect. The results showed that under the blockchain decision-making model, the development level of water management, the new energy economy, and their coordinated development level in 2013 were 0.527, 0.535, and 0.602, respectively. In 2022, their development levels reached 0.556, 0.564, and 0.634, respectively.
Research on river water quality evaluation based on the GA-PP and improved fuzzy model
Authors: Huo Zhenggang , Zha Xiaoting , Chu Yuhong , Lu Mengyao , Zhang Sensen 
Published: October 2023

Abstract

To ensure the water quality of rivers, it is crucial to scientifically evaluate their water quality status. This study takes a river in Jiangsu, China, as an example to establish six targeted main indicators for river water quality evaluation and uses a projection pursuit model optimized by the genetic algorithm to determine weights. Applying the improved fuzzy evaluation model to the final evaluation of water quality, the results indicate that this article adopts a weight calculation model that reduces dimensionality without losing data features, and the comprehensive evaluation model is also more complete, resulting in more accurate evaluation results. According to model analysis, the summer water quality is good and peaks from June to July. This article proposes corresponding measures and suggestions in response to the reasons behind this seasonal change. The evaluation model used in this article is superior to other models in terms of accuracy and portability, making it an excellent choice for river water quality evaluation. It can provide valuable technical guidance for similar river water quality evaluations.
Molecular genetic subtypes of bladder cancer
Authors: Kotov S. V. , Khachatryan A. L. , Sargsyan Sh. M. 
Published: October 2023

Introduction. Bladder cancer (BCa) is one of the most common oncological diseases with many relapses and progressions, which requires more and more new ways to solve this problem.Objective. To analyse of existing data on the molecular and genetic features of BCa classification based on them, assessment of the possibility of its introduction into clinical practice as a criterion for recurrence and progression.Materials & methods. We analysed the data of studies on molecular subtypes of BCa published in PubMed, Scientific Electronic Library of Russia (eLibrary), Scopus, Medline, EMBASE, websites of professional associations. We searched the following keywords: "molecular subtypes of bladder cancer", "non-muscle invasive bladder cancer", "molecular subtypes of bladder cancer" "non-muscle invasive bladder cancer". The paper focuses on the current classifications and the April 2020 consensus, which can be universal and applied in everyday practice.Results. During the analysis of the obtained data, it was revealed that the molecular and genetic heterogeneity of BCa is reflected not only in the proteins expressed on tumor cells, but also in the response to treatment and prognosis of the disease.Conclusion. Molecular and genetic markers seem promising for introduction into wide clinical practice to adjust treatment and assess the risks of recurrence and progression.
Coronary heart disease and the course of newly detected prostate cancer
Authors: Pomeshkin E. V. , Popov S. V. , Orlov I. N. , Bragin-Maltsev A. I. , Pomeshkina S. A. , Barbarash O. L. 
Published: October 2023

Introduction. In recent years, the clinical and practical interest in malignant neoplasms and diseases of the cardiovascular system has been extremely high. These nosologies are the leading causes of hospitalisations and deaths worldwide.Objective. To assess the prevalence of coronary heart disease and risk factors among patients with newly diagnosed prostate cancer, as well as to identify their relationship with the severity of prostate cancer.Materials & methods. The study included 140 newly diagnosed prostate cancer (PCa) patients with a median age of 65 [62; 70] years. All patients had the level of prostate-specific antigen, pelvic MRI, prostate biopsy with determination of Gleason score, all patients filled out the questionnaire of the International Index of Erectile Function (IIEF-5). Depending on the presence of coronary heart disease (CHD), all patients were divided into two groups: Group 1 — 94 (67%) PCa patients without CHD; Group 2 — 46 (33%) PCa patients with CHDResults. In a comparative analysis, the groups did not differ in indicators such as age, BMI, prostate volume, incidence of diabetes mellitus type 2, and lipid status level. However, in PCa patients with CHD, erectile dysfunction was statistically significantly more pronounced than in patients without CHD (10 vs 18 IIEF5 points, p = 0.03), respectively. In terms of PSA levels, it turned out that in Group 2, this indicator was significantly higher than in Group 1 (15.8 ng/ml vs 10.1 ng/ml, p = 0.03), respectively, which indicates possibly more high malignancy of the process. Furthermore, in Group 2, patients with a high grade PCa according to the classification of The International Society of Urological Pathology (ISUP) 4 / 5 were statistically significantly more common compared to patients of Group 1 (12 (26%) vs. 10 (11%), p = 0.01), respectively. In a comparative analysis of patients depending on the risk of a possible PCa recurrence of , which was taken into account by such parameters as PSA level, Gleason index + ISUP grade, it turned out that in Group 2 there were statistically significantly more patients with a higher risk of PCa progression compared to Group 1 (20 (44%) vs 26 (28%), p = 0.02), respectively.Conclusion. PCa patients with concomitant CHD are characterized by a higher waist circumference, they had lower indicators of erectile function, a more pronounced comorbid background, and more often had a history of stroke. In addition, PCa patients with CHD had a high grade PCa and a higher risk of PCa progression.
Empowerment Enabled by Information and Communications Technology and Intention to Sustain a Healthy Behavior: Survey of General Users
Authors: Alluhaidan Ala Saleh , Chatterjee Samir , Drew David E , Ractham Peter , Kaewkitipong Laddawan 
Published: October 2023

Background
Most people with chronic conditions fail to adhere to self-management behavioral guidelines. In the last 2 decades, several mobile health apps and IT-based systems have been designed and developed to help patients change and sustain their healthy behaviors. However, these systems often lead to short-term behavior change or adherence while the goal is to engage the population toward long-term behavior change.

Objective
This study aims to contribute to the development of long-term health behavior changes or to help people sustain their healthy behavior. For this purpose, we built and tested a theoretical model that includes enablers of empowerment and an intention to sustain a healthy behavior when patients are assisted by information and communications technology.

Methods
Structural equation modeling was used to analyze 427 survey returns collected from a diverse population of participants and patients. Notably, the model testing was performed for physical activity as a generally desirable healthy goal.

Results
Message aligned with personal goals, familiarity with technology tools, high self-efficacy, social connection, and community support played a significant role (P<.001) in empowering individuals to maintain a healthy behavior. The feeling of being empowered exhibited a strong influence, with a path coefficient of 0.681 on an intention to sustain healthy behavior.

Conclusions
The uniqueness of this model is its recognition of needs (ie, social connection, community support, and self-efficacy) to sustain a healthy behavior. Individuals are empowered when they are assisted by family and community, specifically when they possess the knowledge, skills, and self-awareness to ascertain and achieve their goals. This nascent theory explains what might lead to more sustainable behavior change and is meant to help designers build better apps that enable people to conduct self-care routines and sustain their behavior.
Rosacea and Its Association With Malignancy: Systematic Review
Authors: Thapa Luna , Xia Joyce , Guo William , Usmani Hunya , Miller Devin , Lozeau Daniel 
Published: October 2023

Background
Rosacea is a chronic inflammatory skin condition that predominantly manifests as facial flushing, irritation, and acne. Rosacea and cancer are thought to be linked by the commonality of inflammatory and immune response dysfunction. Studies that have looked into this possible association have reported mixed results.

Objective
Given the conflicting literature on this topic, our study sought to evaluate the overall association between rosacea and several cancers commonly investigated in the literature.

Methods
A systematic review was conducted using the Cochrane, PubMed, Embase, and Ovid databases. Studies were screened independently for inclusion of rosacea and glioma and breast, thyroid, hepatic, or skin cancers. Using information from the articles, rosacea and each cancer were categorized as having a positive, negative, or unclear association.

Results
Our systematic review included 39 full-text studies that investigated the association between rosacea and various malignancies. Among the malignancies of concern, 41% (16/39) of the studies reported an association with basal cell carcinoma, with 2 cohorts revealing an adjusted risk ratio (RR) of 1.50 (95% CI 1.35-1.67) and 0.72 (95% CI 0.56-0.93). In total, 33% (13/39) of the studies reported an association with squamous cell carcinoma, with 2 cohorts revealing an adjusted RR of 1.4 (95% CI 1.02-1.93) and 1.30 (95% CI 0.90-1.88). A total of 8% (3/39) of the studies reported an association between breast cancer and melanoma, with breast cancer cohorts revealing an adjusted RR of 8.453 (95% CI 1.638-43.606), 1.03 (95% CI 0.89-1.20), and 1.36 (95% CI 1.18-1.58) and melanoma cohorts revealing an adjusted RR of 1.10 (95% CI 0.95-1.27), 0.63 (95% CI 0.47-0.85), and 0.96 (95% CI 0.57-1.62). A total of 5% (2/39) of the studies reported an association among nonmelanoma skin cancers, hepatic cancer, and thyroid carcinomas, with nonmelanoma skin cancer cohorts revealing an adjusted RR of 1.36 (95% CI 1.26-1.47) and 2.66 (95% CI 1.53-4.61), hepatic cancer cohorts revealing an adjusted RR of 1.42 (95% CI 1.06-1.90) and 1.32 (95% CI 0.89-1.95), and thyroid carcinoma cohorts revealing an adjusted RR of 1.06 (95% CI 0.68-1.65) and 1.59 (95% CI 1.07-2.36). Only 1 cohort reported an association with glioma, revealing an adjusted RR of 1.36 (95% CI 1.18-1.58). According to our review, patients with rosacea were statistically more likely to have nonmelanoma skin cancers, breast cancer, and glioma. Rosacea was not found to be substantially associated with melanoma. The associations between rosacea and hepatic and thyroid cancers were unclear because of conflicting results.

Conclusions
The current literature shows that rosacea is significantly associated with increased odds of nonmelanoma skin cancers, glioma, and breast cancer. Rosacea does not appear to be associated with melanoma. Further studies should be conducted to clarify the association between thyroid and hepatic cancers and rosacea.
Digital Rehabilitation Interventions in Sub-Saharan Africa: Protocol for a Scoping Review
Authors: Oduor Michael , Korniloff Katariina , Gasana Juliette , Tumusiime David K , Aartolahti Eeva 
Published: October 2023

Background
Estimations show that at least one in every 3 people in the world needs rehabilitation at some point in the course of their illness or injury. Access to rehabilitation services is an essential part of the continuum of care and is integral to achieving universal health coverage. However, most of the world’s population living in low- and middle-income countries, especially in the sub-Saharan African region, does not have access to adequate rehabilitation services. Wider adoption of digital solutions offers opportunities to support and enhance access to rehabilitation services in sub-Saharan Africa. A region where there is a greater burden and need for these services. There is also little published research about digital rehabilitation in sub-Saharan Africa, as it is an underexamined topic in the region.

Objective
This scoping review aims to provide a comprehensive picture of the current evidence of digital interventions in rehabilitation implemented in any health, social, educational, or community setting in the sub-Saharan Africa region.

Methods
We will conduct a scoping review using Arksey and O’Malley’s methodological framework and follow the Joanna Briggs Institute methodology for scoping reviews. We will develop search strategies for a selected number of web-based databases, search for peer-reviewed scientific publications until September 2023, and screen the reference lists of relevant articles. We will include research articles if they describe or report the use of digital interventions in the rehabilitation of patients with any health problem or disability in sub-Saharan Africa. For selected articles, we will extract data using a customized data extraction form and use thematic analysis to compare the findings across studies.

Results
The preliminary database search in MEDLINE (EBSCO) was completed in May 2023. The research team will conduct a search of relevant articles in the autumn. The results will be synthesized and reported under the key conceptual categories of this review, and we expect the final scoping review to be ready for submission in early 2024.

Conclusions
We expect to find gaps in the research and a lack of detailed information about digital rehabilitation interventions in sub-Saharan Africa, as well as potential areas for further study. We will identify opportunities to inform the development of digital rehabilitation interventions.

International Registered Report Identifier (IRRID)
PRR1-10.2196/48952
El Camino del Inca en el salar de Ascotán
Authors: Stehberg Rubén , Cárdenas Ulises , Cerda Córdova Juan Carlos 
Published: October 2023

This paper describes a 24 km subsection of the Inca Trail. Located in the eastern part of the Salar de Ascotán (salt flat) in the mountains along the Chile-Bolivia border, the route is quite straight and free of major obstacles, making it possible for a llama caravan to travel in a single day. This subsection has been subdivided into three segments of 578 m, 4,847 m and 18,613 m, according to their placement relative to the architectural facilities at Chac-Inga (UTM 589790N7590546E; 3731 m) and Tres Ojos de Agua de Ascotán (UTM578508N -7611392E; 4242 m), both of which appear to have been roadside tambos (inns) from the Tawantinsuyu period. Studies recorded the architectural features of the route, identifying its axis, the roadway, roadside architecture and the associated sites and elements. Landscape-geographic analysis focused on the visibility of the road and its interaction with the local and regional population. Researchers also examined the processes of continuity and change experienced by the road over time. Finally, this paper describes the Ruinas de una antigua posada (Ruins of an old roadside inn) site, possibly of Inca origin, and the Incan ceremonial structure at 5,200 m altitude on Cerro El Jardín or Ascotán.