bluuebunny/crossref_metadata_2025_split huggingface dataset:
Mechanical Durability and Flexibility in Perovskite Photovoltaics: Advancements and Applications
Authors: Song Fei , Zheng Dexu , Feng Jiangshan , Liu Jishuang , Ye Tao , Li Zhipeng , Wang Kai , Liu Shengzhong (Frank) , Yang Dong 
Published: January 2024

AbstractThe remarkable progress in perovskite solar cell (PSC) technology has witnessed a remarkable leap in efficiency within the past decade. As this technology continues to mature, flexible PSCs (F‐PSCs) are emerging as pivotal components for a wide array of applications, spanning from powering portable electronics and wearable devices to integrating seamlessly into electronic textiles and large‐scale industrial roofing. F‐PSCs characterized by their lightweight, mechanical flexibility, and adaptability for cost‐effective roll‐to‐roll manufacturing, hold immense commercial potential. However, the persistent concerns regarding the overall stability and mechanical robustness of these devices loom large. This comprehensive review delves into recent strides made in enhancing the mechanical stability of F‐PSCs. It covers a spectrum of crucial aspects, encompassing perovskite material optimization, precise crystal grain regulation, film quality enhancement, strategic interface engineering, innovational developed flexible transparent electrodes, judicious substrate selection, and the integration of various functional layers. By collating and analyzing these dedicated research endeavors, this review illuminates the current landscape of progress in addressing the challenges surrounding mechanical stability. Furthermore, it provides valuable insights into the persistent obstacles and bottlenecks that demand attention and innovative solutions in the field of F‐PSCs.
Updated CRUSADE score to predict in‐hospital bleeding: External validation in the Thai percutaneous coronary intervention registry
Authors: Chichareon Ply , Chamnarnphol Noppadol , Chandavimol Mann , Suwannasom Pannipa , Roongsangmanoon Worawut , Limpijankit Thosaphol , Srimahachota Suphot , Athisakul Siriporn , Hutayanon Pisit , Kiatchoosakun Songsak , Udayachalerm Wasan , Thakkinstian Ammarin , Sansanayudh Nakarin 
Published: January 2024

AbstractBackgroundThe Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines (CRUSADE) score has been recommended to predict in‐hospital bleeding risk in non‐ST segment elevation myocardial infarction (NSTEMI) patients. The evaluation of the CRUSADE risk score in Asian patients undergoing contemporary percutaneous coronary intervention (PCI) for NSTEMI is necessary.AimsWe aimed to validate and update the CRUSADE score to predict in‐hospital major bleeding in NSTEMI patients treated with PCI.MethodThe Thai PCI registry is a large, prospective, multicenter PCI registry in Thailand enrolling patients between May 2018 and August 2019. The CRUSADE score was calculated based on 8 predictors including sex, diabetes, prior vascular disease (PVD), congestive heart failure (CHF), creatinine clearance (CrCl), hematocrit, systolic blood pressure, and heart rate (HR). The score was fitted to in‐hospital major bleeding using the logistic regression. The original score was revised and updated for simplification.ResultsOf 19,701 patients in the Thai PCI registry, 5976 patients presented with NSTEMI. The CRUSADE score was calculated in 5882 patients who had all variables of the score available. Thirty‐five percent were female, with a median age of 65.1 years. The proportion of diabetes, PVD, and CHF was 46%, 7.9%, and 11.2%, respectively. The original and revised models of the CRUSADE risk score had C‐statistics of 0.817 (95% CI: 0.762–0.871) and 0.839 (95% CI: 0.789–0.889) respectively. The simplified CRUSADE score which contained only four variables (hematocrit, CrCl, HR, and CHF), had C‐statistics of 0.837 (0.787–0.886). The calibration of the recalibrated, revised, and simplified model was optimal.ConclusionsThe full and simplified CRUSADE scores performed well in NSTEMI treated with PCI in Thai population.
Structural equation models for simultaneous modeling of air pollutants
Authors: Bottazzi Schenone Mariaelena , Grimaccia Elena , Vichi Maurizio 
Published: January 2024

AbstractThis paper provides a new modeling for air pollution, simultaneously taking into account the six main pollutants (PM10 and PM2.5, Sulphate Dioxide, Nitrogen Dioxide, Carbon Monoxide, ground level Ozone concentrations) and their key determinants, employing Structural Equation Models (SEMs). The model is able to estimate the complex links among air pollutants, often neglected in literature, and identifies specific drivers of air pollution. In literature, indexes of air pollution achieved using a fully statistical methodology have not been proposed yet. Indeed, an added value of this proposal is the statistical procedure itself, which can be applied also to obtain indexes modeling different phenomena. In particular, in this study, the new Air Pollution Index (API) is based on a modeling approach that allows to assess, through statistical criteria, the goodness of fit of the SEM in modeling pollutants and the significance of their determinants. The performance of the new index is assessed using air quality data for municipal European areas, which are characterized by different socioeconomic, geographical, and meteorological features. SEMs are estimated and evaluated in terms of best fit and model complexity. The index resulting by the best SEM is compared with the well‐established Air Quality Index (AQI). The new API is validated by means of a sensitivity analysis, performed with a simulation study. Finally, to visualize the meaningfulness of the obtained results, a model‐based cluster analysis is estimated on the municipal areas. The proposed SEM contributes to a better understanding of the relationships between air pollutants and their determinants, and this knowledge can inform policy decisions aimed at reducing air pollution and improving public health.
An open, multicenter, exploratory study of apatinib mesylate maintenance therapy for recurrent/metastatic head and neck squamous cell carcinoma (ChiCTR1800019375)
Authors: Wei Jinlong , Su Jing , Wang Jianfeng , Jia Xiaojing , Zhao Qin , Shi Weiyan , Wang Huanhuan , Zheng Zhuangzhuang , Jiang Xin 
Published: January 2024

AbstractBackgroundThis study evaluated the efficacy of apatinib in maintenance therapy in patients with recurrent/metastatic head and neck squamous cell carcinoma (R/M HNSCC).MethodsTwenty‐six patients from three centers were enrolled from November 2018 to September 2021. These patients received 2 weeks apatinib, administered at 250 mg qd. Then apatinib dose may be administered to 500 mg qd continuous in 4 weeks cycle if no patients experienced adverse reaction. Enrolled patients can receive a combination of radiotherapy or chemotherapy. The primary endpoints were progression‐free survival (PFS), and secondary endpoints included overall survival (OS), disease control rate (DCR), objective response rate (ORR), quality of life (QOL) score, and adverse drug reactions.ResultsMedian PFS of all patients was 3.2 months (95% CI: 2.06–4.33). Median OS of all patients was 7.3 months (95% CI: 2.14–12.46). The DCR was 92.3%. The ORR was 30.8%. In univariate analysis, the results showed that ECOG score 0–1 (HR = 0.31, p = 0.006) and treated with apatinib for more than 60 days (HR = 0.31, p = 0.003) were independent prognostic indicators affecting PFS, and ECOG score 0–1 (HR = 0.40, p = 0.027) and moderately differentiated or highly differentiated (HR = 0.38, p = 0.048) were independent prognostic indicators of OS. The most common adverse events among treated subjects included hypertension (46.1%), fatigue (42.3%), and hand‐foot syndrome (23.1%). There were only two cases (7.7%) of Grade III or above adverse reactions.ConclusionsMaintenance therapy with apatinib is an effective and well‐tolerated regimen in patients with R/M HNSCC.
A nonradiographic strategy to real‐time monitor the position of three‐dimensional‐printed medical orthopedic implants by embedding superparamagnetic Fe3O4 particles
Authors: Li Yike , Chen Peng , Wu Zhenhua , Shi Congcan , Chen Peng , Xu Yizhuo , Chen Xiaojun , Chen Manhui , Li Yuxin , Yan Chunze , Shi Yunsong , Su Bin 
Published: January 2024

AbstractMonitoring the position of orthopedic implants in vivo is paramount for enhancing postoperative rehabilitation. Traditional radiographic methods, although effective, pose inconveniences to patients in terms of specialized equipment requirements and delays in rehabilitation adjustment. Here, a nonradiographic design concept for real‐time and precisely monitoring the position of in vivo orthopedic implants is presented. The monitoring system encompasses an external magnetic field, a three‐dimensional (3D)‐printed superparamagnetic intervertebral body fusion cage (SIBFC), and a magnetometer. The SIBFC with a polyetheretherketone framework and a superparamagnetic Fe3O4 component was integrally fabricated by the high‐temperature selective laser sintering technology. Owing to the superparamagnetic component, the minor migration of SIBFC within the spine would cause the distribution change of the magnetic induction intensities, which can be monitored in real‐time by the magnetometer no matter in the static states or dynamic bending motions. Besides horizontal migration, occurrences of intervertebral subsidence in the vertical plane of the vertebrae can also be effectively distinguished based on the obtained characteristic variations of magnetic induction intensities. This strategy exemplifies the potential of superparamagnetic Fe3O4 particles in equipping 3D‐printed orthopedic implants with wireless monitoring capabilities, holding promise for aiding patients' rehabilitation.
FIGO position statement on comprehensive sexuality education
Authors: Koch Mikaela , Tyson Nichole , Bhuinneain G. Meabh Ni , Kasliwal Asha , Conry Jeanne , Sridhar Aparna 
Published: January 2024

AbstractNow is a pivotal moment in the fight for reproductive health and justice internationally. Well‐established research has recognized the benefits of comprehensive sexuality education for youth and adolescents—including vast reproductive health benefits, decreased interpersonal violence, and improvements on measures of academic success and well‐being. Despite these established benefits, challenges to the implementation of culturally sensitive and holistically framed sexuality education are intensifying across the globe. The International Federation of Gynecology and Obstetrics (FIGO) stands firmly in its support of comprehensive sexuality education and re‐emphasizes the importance of the implementation of scientifically accurate, age‐appropriate, culturally relevant, and inclusive education. Successful implementation relies on active youth leadership, physician involvement, and a renewed focus on high‐quality monitoring mechanisms to assess impact and accountability at all levels. Most importantly, future efforts to improve and scale comprehensive sexuality education must emphasize the importance of an inclusive curriculum that addresses previously marginalized youth, such as LGTBQ+ and disabled individuals, through a reproductive justice lens. FIGO commits, and encourages the international healthcare community, to provide continued advocacy for the rights to health, education, and equality, in order to achieve improvement in health outcomes for young people across the globe.
Channel estimation for underwater acoustic OFDM based on super‐resolution network
Authors: Cui Xuerong , Yuan Bin , Li Juan , Jiang Bin , Li Shibao , Liu Jianhang 
Published: January 2024

AbstractIn this letter, we propose a method for underwater acoustic channel estimation that combines image super‐resolution (SR) and is named FCDnNet. FCDnNet consists of two parts: Fast Super Resolution Convolutional Neural Network (FSRCNN) and Complex Denoising Convolutional Neural Network (C‐DnCNN). FSRCNN extracts effective features of pilot channels, uses deconvolution to achieve SR reconstruction, and generates a pre‐estimation channel matrix. C‐DnCNN preserves the relative positions of the real and imaginary parts of the channel, fully utilizing amplitude and phase information, and can more effectively recover the channel matrix from the pre‐estimation matrix. Experimental results show that the normalized mean square error (NMSE) of FCDnNet is at least 13.1–65.2 lower than other channel estimation methods based on deep learning.
An optimized system for sensor ontology meta‐matching using swarm intelligent algorithm
Authors: Lateef Haroon P S Abdul , Patil Sujata N. , Bidare Divakarachari Parameshachari , Falkowski‐Gilski Przemysław , Rafeeq M. D. 
Published: January 2024

AbstractIt is beneficial to annotate sensor data with distinct sensor ontologies in order to facilitate interoperability among different sensor systems. However, for this interoperability to be possible, comparable sensor ontologies are required since it is essential to make meaningful links between relevant sensor data. Swarm Intelligent Algorithms (SIAs), namely the Beetle Swarm Optimisation Algorithm (BSO), present a possible answer to ontology matching problems. This research focuses on a method for optimizing ontology alignment that employs BSO. A novel method for effectively controlling memory use and striking a balance between algorithm exploration and exploitation is proposed: the Simulated Annealing‐based Beetle Swarm Optimisation Algorithm (SA‐BSO). Utilizing Gray code for solution encoding, two compact operators for exploitation and exploration, and Probability Vectors (PVs) for swarming choosing exploitation and exploration, SA‐BSO combines simulated annealing with the beetle search process. Through inter‐swarm communication in every generation, SA‐BSO improves search efficiency in addressing sensor ontology matching. Three pairs of real sensor ontologies and the Conference track were used in the study to assess SA‐BSO's efficacy. Statistics show that SA‐BSO‐based ontology matching successfully aligns sensor ontologies and other general ontologies, particularly in conference planning scenarios.
Evaluating a novel pharmacist‐led buprenorphine outreach service for treatment of opioid use disorder in individuals residing in supportive housing
Authors: Ly Janice , Peterson Damian , Geier Michelle 
Published: January 2024

AbstractIntroductionIn San Francisco, there were 638 accidental overdose deaths involving opioids in 2022 alone, with opioid overdoses occurring at a disproportionate rate in the Black population and in those with fixed housing. Past studies attempting to address such disparities suggest that low‐barrier buprenorphine (BUP) treatment models may improve patient engagement and retention in care for marginalized populations. While such models have been studied among persons experiencing houselessness (PEH), less is known about the effects of such treatment models among individuals residing in permanent supportive housing (PSH).ObjectivesTo evaluate the impact of an innovative pharmacist‐led pilot service in providing more equitable and accessible BUP treatment to individuals residing in PSH.MethodsThis was a 3‐month pre‐and‐post interventional pilot study to evaluate the impact of a novel pharmacist‐led outreach service on patient engagement in treatment with BUP for Opioid Use Disorder (OUD). The primary endpoint was treatment adherence, defined as 80% prescription days covered (PDC) in a 3‐month period. Secondary endpoints included change in PDC, linkage to office‐based care, incidence of overdose, emergency department (ED) presentations, and hospital admissions, as well as successful BUP initiation.ResultsThirty‐eight patients were enrolled in the pharmacist‐led BUP outreach service. Among the 38 patients, the mean age was 46 years and 16 (42%) were Black. Engagement with the service was associated with increased treatment adherence, with 14 patients (37%) achieving ≥80% PDC post‐intervention compared to 1 patient (3%) pre‐intervention (p = 0.0009).ConclusionA pharmacist‐led BUP outreach service was found to increase treatment adherence in individuals residing in PSH over 3 months. Low‐barrier BUP treatment models, such as that evaluated in this study, may help provide more equitable and accessible care that is critical in addressing the socioeconomic and racial disparities in opioid overdose deaths.
Nationwide evaluation of the clinical impact of acute care adult medicine pharmacists
Authors: Szwak Jennifer A. , Assadi Rizah Anwar , Gonzalez Jimmy , Hong Lisa T. , Meyenburg Lyndsi K. , Miesner Andrew R. , Steuber Taylor , Fritz Megan Kunka 
Published: January 2024

AbstractIntroductionThe impact of pharmacists has been described for many practice areas including critical care, emergency medicine, and transitions of care. Literature describing the extensive role of adult medicine (AMED) clinical pharmacists in the inpatient setting is limited.ObjectiveThe objective of this study was to characterize clinical activities performed by inpatient AMED pharmacists nationally.MethodsThis was a multicenter, prospective, observational study including AMED pharmacists who spend more than 50% of their time practicing in the acute care setting. A 65‐item electronic survey was developed and distributed to members of the American College of Clinical Pharmacy AMED Practice and Research Network (PRN). The survey collected demographics, clinical interventions, rates of intervention acceptance, and the significance of those interventions, where applicable. Respondents were asked to report all interventions made over any one‐week period while providing direct patient care. Descriptive statistics were used to summarize data. Chi‐square tests and Wilcoxon rank sum tests were used to compare nominal and continuous data, respectively.ResultsThirty three pharmacists representing 988.5 h of direct patient care reported activities, including profile review (97%), daily rounding with prescribers (94%), patient education (76%), and order entry or verification (64%). During the study period, 4488 interventions were documented. The most common interventions and activities documented were optimization of therapy (n = 1125, 25%), initiation of therapy (n = 770, 17%), and interpretation of diagnostic data or lab values (n = 331, 7%). The top three therapeutic classes with interventions were antimicrobials (n = 473, 25%), cardiovascular medications (n = 248, 13%), and antithrombotics (n = 190, 10%). Of the applicable interventions, 2775 (89%) were accepted, 2541 (81%) were pharmacist‐initiated, and 277 (9%) were classified as serious or very/extremely significant interventions.ConclusionAMED pharmacists provide diverse recommendations across numerous medication therapeutic categories that are highly accepted. AMED pharmacists play an important role in optimizing medication use through care team and patient interactions.
Evaluation of a psychiatric pharmacist consultation service in a multispecialty outpatient clinic
Authors: Hui Deni , Chibli Dina , Catanzano Samantha 
Published: January 2024

AbstractBackgroundIntegrated care programs provide both medical and mental health care in clinical settings. Psychiatric pharmacists play a key role in optimizing patient care when integrated into a healthcare team. This project describes the implementation and trends of a psychiatric pharmacist consultation service in a multispecialty outpatient through an integrated behavioral healthcare model.MethodsThis is a retrospective study analyzing a psychiatric pharmacist consultation service at an academic multispecialty outpatient clinic. Eligible patients were aged ≥17 years and seen by the psychiatric pharmacist between June 1, 2019 and June 30, 2022. Patient demographics, reasons for referral, and pharmacist interventions were collected. Patient outcomes on depression, anxiety, and diabetes were also explored. Descriptive statistics were used to quantify information.ResultsA total of 572 encounters were identified. Of those, 285 (49.8%) represented unique patients. Over the 36‐month period, an average of 16 consults were conducted per month. Anxiety and depressive disorders, pain syndromes, and adult attention‐deficit/hyperactivity disorder were the most common diagnoses listed as reasons for consultation. An average of five recommendations or interventions were provided by the psychiatric pharmacist at each initial consultation. Anxiety and depression symptom scores, as well as hemoglobin A1c (HbA1c) values, were lower following pharmacist consultation.ConclusionPsychiatric pharmacists can serve a unique role at multispecialty clinics by providing consultation for patients with psychiatric conditions, chronic pain, medical conditions, and polypharmacy. This study demonstrates the successful utilization of such a service and suggests a psychiatric pharmacist's expertise contributes to improved depression, anxiety, and glycemic outcomes. The multispecialty outpatient setting represents an opportunity to further explore growth for psychiatric pharmacists and the impact these services have on patient outcomes.
Evaluation of single maintenance and reliever therapy (SMART) prescribing of budesonide‐formoterol for asthma after a clinical pharmacist‐led initiative
Authors: Harris Ila M. , Philbrick Ann M. , Klemenhagen Kristen C. 
Published: January 2024

AbstractIntroductionSingle maintenance and reliever therapy (SMART) with a combination inhaled corticosteroid‐formoterol inhaler is the preferred asthma treatment by the Global Initiative for Asthma and the National Asthma Education and Prevention Program guidelines. These recommendations have been slow to be implemented routinely into clinical practice.MethodsThis was an observational cohort study conducted in a family medicine residency program clinic. A clinical pharmacist‐led initiative to implement SMART, which included provider education and the development of clinical tools to facilitate SMART prescribing, was assessed. Year 1 (Y1; pre‐intervention) and year 2 (Y2; post‐intervention) were compared.OutcomesThe primary outcome was to evaluate the impact of this initiative on the frequency of SMART (budesonide‐formoterol without albuterol) prescribing. Prescription frequencies for albuterol and budesonide‐formoterol were also compared separately. Secondary outcomes were Asthma Control Test (ACT) scores and prescribing frequencies among faculty and resident physicians.ResultsThe total number of eligible patients in the clinic population was 807, and 459 of these patients met the inclusion criteria. There were more females than males, and the mean age was 39. About 24% had a language preference other than English and 22% required an interpreter. The percentage of patients who were prescribed SMART significantly increased from 0.44% to 11.5% (p < 0.001). Budesonide‐formoterol prescriptions increased from 7.4% to 34.6% (p < 0.001). Albuterol metered‐dose inhaler prescriptions decreased from 79.7% to 66.2% (p < 0.001). Prescribing patterns were similar for patients of faculty physicians (n = 258) and resident physicians (n = 196). Only 164 (35.7%) patients had an ACT score in Y1 and Y2, and the mean ACT score was not significantly different between Y1 and Y2 (p = 0.973).ConclusionA clinical pharmacist‐led SMART asthma prescribing initiative was associated with a significant increase in SMART prescribing, a significant increase in budesonide‐formoterol prescribing, and a significant decrease in albuterol prescribing.