bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anatomical analysis of the femoral condyle in normal and osteoarthritic knees
Authors: Matsuda Shuichi , Miura Hiromasa , Nagamine Ryuji , Mawatari Taro , Tokunaga Masami , Nabeyama Ryotaro , Iwamoto Yukihide 
Published: June 2003

AbstractIt is important to understand anatomical feature of the distal femoral condyle for treatment of osteoarthritic knees. Detailed measurement of the femoral condyle geometry, however, has not been available in osteoarthritic knees including valgus deformity. This study evaluated femoral condyle geometry in 30 normal knees, 30 osteoarthritic knees with varus deformity, and 30 osteoarthritic knees with valgus deformity using radiographs and magnetic resonance imaging (MRI). In radiographic analysis in the coronal plane, the femoral joint angle (lateral angle between the femoral anatomic axis and a tangent to femoral condyles) was 83.3° in the normal knees, 83.8° in the varus knees, and 80.7° in the valgus knees. In MRI analysis in the axial plane, the posterior condylar tangent showed 6.4° of internal rotation relative to the transepicondylar axis in the normal knees, 6.1° in the varus knees, and 11.5° in the valgus knees. These results suggested that there was no hypoplasia of the medial condyle in the varus knees, but the lateral condyle in the valgus knees was severely distorted. Surgeons should take this deformity of the lateral femoral condyle into account when total knee arthroplasty is performed for a valgus knee. © 2003 Orthopaedic Research Society. Published by Elsevier Ltd. All rights reserved.
The dexamethasone suppression test and CSF-5-HIAA in relation to suicidality and depression in suicide attempters
Authors: Westrin Åsa , Niméus Anders 
Published: June 2003

AbstractThis study tested suicidality in relation to cerebrospinal fluid (CSF) 5-hydroxyindoleacetic acid (5-HIAA) and the dexamethasone suppression test. Patients with nonsuppression of cortisol had the highest scores of the Suicide Assessment Scale (SUAS) and the Montgomery Asberg Depression Rating Scale (MADRS), respectively (P< 0.05;P< 0.01). The results persisted when analysed for covariance with CSF-5-HIAA. We have previously noted an elevated suicide risk in suicide attempters with high SUAS-scores, why a large part of nonsuppressors may be at high risk for future suicide.
A psychopathological study of a group of schizophrenic patients after attempting suicide. Are there two different clinical subtypes?
Authors: Aguilar E.J. , Leal C. , Acosta F.J. , Cejas M.R. , Fernández L. , Gracia R. 
Published: June 2003

AbstractFifty-six schizophrenic patients at the moment of their suicidal attempt were compared to a control group of 60 patients. Schizophrenic suicidal attempters showed an identifiable clinical profile at the acute phase. Two main groups could be differentiated in regard to their reasons (depressive or psychotic) for attempting suicide.
Sampling variance of species identification in fisheries acoustic surveys based on automated procedures associating acoustic images and trawl hauls
Authors: Petitgas Pierre , Massé Jacques , Beillois Pierre , Lebarbier Emilie , Le Cann Arnaud 
Published: June 2003

Abstract
During the acoustic surveys of fish stocks, a small number of echo traces are identified to species by fishing. During data analysis, the process of echogram scrutiny leads to allocating echo-trace backscattered energies to species. While the precision of survey estimates is generally based on the spatial variation in the energy, no variance term accounts for species identification and energy allocation. In this paper, the sampling variance of species identification is developed and automated procedures are used allowing energy allocation to be carried out by a non-expert. The procedures are based on the fact that at the sampling stage trawl hauls are linked with particular acoustic images. The procedures have two steps: the classification step corresponds to species identification and the aggregation step to energy allocation. Classification is performed on the identified images and results in defining groups of images and estimating in each the sampling variability of the species identification. Aggregation is performed on non-identified images and results in post-stratifying the data. The estimation (map, abundance and variance per species) is then derived automatically and is conditioned by the post-stratification. Two approaches are followed, one based on the echo-trace characteristics making full use of the echogram (acoustic-image classification) and the other on the spatial continuity of the species composition between trawl hauls (trawl-haul classification). These methods are described and compared. The species-identification variance term is also compared to the spatial variance.
Evaluation of a Doppler sonar system for fisheries applications
Authors: Tollefsen Cristina D.S , Zedel Len 
Published: June 2003

Abstract
We report on tests of a general-purpose, coherent, Doppler sonar system undertaken to explore its capabilities when applied to detecting discrete fish targets. This 250-kHz, 30 kHz bandwidth instrument provides for phase coding of the transmit pulses and coherent sampling of successive acoustic returns. Towtank tests were used to determine the basic operating capabilities of the system. Under these ideal conditions a single-ping velocity accuracy of between 3 and 8 cm s−1 can be achieved approaching the theoretical limit for this instrument. Field trials were undertaken on the Fraser River in British Columbia near the Pacific Salmon Commission's field site, allowing comparisons with conventional fisheries sonar systems. While the long-term goal is to apply the Doppler sonar system in a larger-scale marine environment, the passage of migrating salmon provides an ideal test opportunity with fish of predictable and well defined swimming behaviour. Individual fish-swimming speed can be measured with an accuracy of between 5 and 10 cm s−1. By comparison, water velocity measurements made with the same instrument can only achieve a theoretical accuracy of 60 cm s−1.
Acoustic seabed classification of marine habitats: studies in the western coastal-shelf area of Portugal
Authors: Freitas Rosa , Silva Susana , Quintino Victor , Rodrigues Ana Maria , Rhynas Karl , Collins William T 
Published: June 2003

Abstract
Two single-beam, seabed-classification systems, QTC VIEW Series IV and QTC VIEW Series V, were used to identify and map biosedimentary gradients in a mid-shelf area off Western Portugal. The survey area has a moderate slope, a depth ranging from 30 to 90 m along a 3.5-km axis perpendicular to the shoreline, and is characterized by smooth sedimentary and biological gradients. Ground truth for sediment grain size and macrofaunal communities was based on grab sampling at 20 sites. The sedimentary and biological data were analysed using classification and ordination techniques. The acoustic data were analysed with qtc impact software and classified into acoustic classes. The affinity groups obtained in each data set were mapped using a Geographics Information System. All showed good agreement and identified prevailing gradients along a northwest–southeast direction. Three acoustic classes were identified, corresponding to the predominant sediment types, namely fine sand with low silt and clay content, silty, very fine sand, and mud. A close relationship with benthic communities was also verified, although less marked because benthic communities continuously change along the northwest–southeast gradient. Overall, the acoustic system coupled with ground-truthing data was able to discriminate and characterize the various benthic biotopes in the survey area.
Pain questionnaires in the analysis of long lasting (chronic) pain conditions
Authors: Wincent Anders , Lidén Ylva , Arnér Staffan 
Published: June 2003

AbstractA study on mainly non‐cancer‐related pain patients was performed concerning clinical patient data used for pain history‐taking and diagnosis. More than 2100 consecutive patients referred to the anaesthetic branch of the Multidisciplinary Pain Centre (MPC) were evaluated at the first visit. The use of a paper questionnaire, including a pain‐drawing and pain intensity Visual Analogue Scale (VAS), was analysed. In a substudy of more than 290 consecutive patients, data from a computerised questionnaire and database was analysed. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaires (EORTC QLQ‐C30) (version 2.0) was used for recording of the Global Health Status/Quality of Life (GHS/QoL) score. The substudy also included the summarized mechanism‐based evaluation of the patients at the first visit, judged by a specialist in pain medicine. The patients' GHS/QoL score was low. The most important pain mechanisms, were nociceptive and peripheral neurogenic. The clinical use of these tools for patient evaluation and for the choice of treatment is suggested. Information technology may be used for analysis of descriptive, evaluative, predictive and prognostic data in pain patients. It can also be used as a tool for clinical pain research towards a mechanism‐based evaluation. Evaluation of patient quality of life and function is suitable for outcome research.
Unsupervised feature selection via two-way ordering
in gene expression analysis
Authors: Ding Chris H.Q. 
Published: June 2003

Abstract
Motivation: Selection of genes most relevant and informative for certain phenotypes is an important aspect in gene expression analysis. Most current methods select genes based on known phenotype information. However, certain set of genes may correspond to new phenotypes which are yet unknown, and it is important to develop novel effective selection methods for their discovery without using any prior phenotype information.
Results: We propose and study a new method to select relevant genes based on their similarity information only. The method relies on a mechanism for discarding irrelevant genes. A two-way ordering of gene expression data can force irrelevant genes towards the middle in the ordering and thus can be discarded. Mechanisms based on variance and principal component analysis are also studied. When applied to expression profiles of colon cancer and leukemia, the unsupervised method outperforms the baseline algorithm that simply uses all genes, and it also selects relevant genes close to those selected using supervised methods.
Supplement: More results and software are online: http://www.nersc.gov/~cding/2way
Contact: chqding@lbl.gov
* To whom correspondence should be addressed.
Graphical methods for class prediction using
dimension reduction techniques on DNA microarray data
Authors: Bura Efstathia , Pfeiffer Ruth M. 
Published: June 2003

Abstract
Motivation: We introduce simple graphical classification and prediction tools for tumor status using gene-expression profiles. They are based on two dimension estimation techniques sliced average variance estimation (SAVE) and sliced inverse regression (SIR). Both SAVE and SIR are used to infer on the dimension of the classification problem and obtain linear combinations of genes that contain sufficient information to predict class membership, such as tumor type. Plots of the estimated directions as well as numerical thresholds estimated from the plots are used to predict tumor classes in cDNA microarrays and the performance of the class predictors is assessed by cross-validation. A microarray simulation study is carried out to compare the power and predictive accuracy of the two methods.
Results: The methods are applied to cDNA microarray data on BRCA1 and BRCA2 mutation carriers as well as sporadic tumors from Hedenfalk et al. (2001). All samples are correctly classified.
Contact: ebura@gwu.edu
* To whom correspondence should be addressed.
Self-injury attendances in the accident and emergency department
Authors: Horrocks Judith , Price Sally , House Allan , Owens David 
Published: June 2003

BackgroundSelf-injury is a neglected area of self-harm research and we know little about its epidemiology, hospital care and outcome.AimsTo provide epidemiological data on self-injury and compare hospital management of self-injury with that for self-poisoning.MethodData were collected on all self-harm attendances to the general hospitals in Leeds over an 18-month period.ResultsPeople attending hospital for self-injury or self-poisoning do not form mutually exclusive groups. There were higher proportions of self-injury episodes compared with self-poisoning, where a history of self-harm or contact with mental health services had been recorded. Fewer psychosocial assessments were carried out after episodes of self-injury compared with self-poisoning but, when they were, follow-up was recommended more often.ConclusionsThe clinical importance of self-injury is not mirrored by the level of psychosocial assessment and after-care provided.
Spontaneous dyskinesia in first-degree relatives of chronically ill, never-treated people with schizophrenia
Authors: McCreadie Robin G. , Thara Rangaswamy , Srinivasan Tirupati N. , Padmavathi Ramachandra 
Published: June 2003

BackgroundWe have suggested recently that there may be a subgroup of schizophrenia, namely schizophrenia with dyskinesia and striatal pathology Might movement disorders be more common in relatives of those with schizophrenia and dyskinesia than in relatives of those without dyskinesia?AimsTo determine the prevalence of abnormal movements in first-degree relatives of people with schizophrenia who themselves do or do not have abnormal movements.MethodChronically ill, never-treated people with schizophrenia in south India (n=70) and their first-degree relatives (n=181) were examined for dyskinesia using the Abnormal Involuntary Movements Scale (AIMS) and for parkinsonism by the Simpson and Angus scale.ResultsOf all relatives, 25 (14%) had dyskinetic movements in at least one body area and 6 (3%) had parkinsonism. Siblings of people with schizophrenia and dyskinesia, compared with siblings of people without dyskinesia, had a higher total AIMS score and more had mild dyskinetic movements in at least one area (5/15 v. 3/34, P=0.04). There were no between-group differences in parkinsonism.ConclusionsDyskinesia but not parkinsonism is more common in siblings of people with schizophrenia who have the corresponding movement disorder.
Early intervention service for non-abusing parents of victims of child sexual abuse
Authors: Forbes Fiona , Duffy John C. , Mok Jacqueline , Lemvig Jette 
Published: June 2003

BackgroundChildhood sexual abuse is a non-specific risk factor for psychopathological disorders in childhood and later life. The response of non-abusing parents to disclosure of abuse may influence the child's outcome.AimsTo assess the level of psychopathological symptoms in parents and children following disclosure of sexual abuse and the changes following a parental treatment intervention.MethodParents completed standardised rating scales about their own and their child's symptoms. These were repeated following the intervention.ResultsThirty-nine parents of 31 children completed scales at the baseline assessment; 18 repeated these following interventions. Initially, parents reported high rates of psychopathological symptoms in themselves and their children, which were reduced following the intervention.ConclusionsThis study confirms the high rates of psychopathological symptoms found in parents of children following disclosure of sexual abuse. Children clinically identified for intervention had higher measured levels of psychopathological symptoms. Targeted treatment interventions are needed.
Dose-Intense Chemotherapy Every 2 Weeks With Dose-Intense Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone May Improve Survival in Intermediate- and High-Grade Lymphoma: A Phase II Study of the Southwest Oncology Group (SWOG 9349)
Authors: Blayney Douglas W. , LeBlanc Michael L. , Grogan Thomas , Gaynor Ellen R. , Chapman Robert A. , Spiridonidis C. Harris , Taylor Sarah A. , Bearman Scott I. , Miller Thomas P. , Fisher Richard I. 
Published: June 2003

Purpose: To test the hypothesis that therapy of intermediate- and high-grade (excluding Burkitt lymphoblastic) lymphoma with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) could be safely dose-intensified with routine filgrastim support. Patients and Methods: Eligible patients were those who were previously untreated and who had either bulky stage II, or stage III or IV lymphoma with working formulation histology D, E, F, G, H, or J; performance status ≤ 2; and acceptable end organ function. No upper age limit was specified. Therapy was dose-intensified CHOP (CHOP-DI) with filgrastim support. Each course was repeated every 14 days for six planned courses. Results: Eighty-eight eligible patients were treated with CHOP-DI and had a median follow-up of 5.1 years on this phase II study, designated Southwest Oncology Group (SWOG) 9349. The progression-free survival was 51% at 2 years and 41% at 5 years. The overall survival was 60% at 5 years. Three fatal treatment-related events occurred. One patient with myelodysplastic syndrome was reported. Conclusion: Treatment with CHOP-DI can be safely administered in the cooperative group setting and results in improved survival. Estimated overall survival at 5 years was 14% better than that of patients treated with standard-dose CHOP in an earlier SWOG study, although progression-free survival of 60% at 2 years—the prespecified end point—was not achieved. CHOP-DI, given every 2 weeks at escalated doses, is a strategy that should be tested in a future randomized clinical trial in lymphoma.
Expression Level of Valosin-Containing Protein Is Strongly Associated With Progression and Prognosis of Gastric Carcinoma
Authors: Yamamoto Shinji , Tomita Yasuhiko , Hoshida Yoshihiko , Takiguchi Shuji , Fujiwara Yoshiyuki , Yasuda Takushi , Yano Masahiko , Nakamori Shoji , Sakon Masato , Monden Morito , Aozasa Katsuyuki 
Published: June 2003

Purpose: Valosin-containing protein (VCP; also known as p97) was shown to be associated with antiapoptotic function and metastasis via activation of nuclear factor kappa-B signaling pathway. In this study, association of VCP expression with recurrence of gastric carcinoma (GC), in which lymphatic vessels are the main route of spread, was examined. Patients and Methods: VCP expression in 330 patients with GC (242 males and 88 females) with ages ranging from 26 to 81 years (median, 60 years) was analyzed by immunohistochemistry, in which staining intensity in tumor cells was categorized as weaker (level 1) or equal to or stronger (level 2) than that in endothelial cells. Results: Ninety-four (28.7%) patient cases showed level 1 and 233 patient cases (71.3%) showed level 2 VCP expression. Patients with level 2 expression showed higher rates of large tumor size (P < .0001), undifferentiated histologic subtype (P < .05), presence of vascular and lymphatic invasion (P < .0001 for both), presence of lymph node metastasis (P < .0001), deep tumor invasion (P < .0001), and poorer disease-free and overall survivals (P < .0001 for both) compared with those with level 1 VCP expression. Multivariate analysis revealed VCP expression level as an independent prognosticator for disease-free and overall survival. VCP level was an indicator for disease-free and overall survival in the early (pT1; P < .01 and P < .05, respectively) and advanced (pT2–4; P < .05 for both) group of pathologic tumor-node-metastasis system classification. Conclusion: The prognostic significance of VCP expression level in GC was demonstrated.
Periodic Mesoporous Organosilicas Functionalized with Sulfonic Acid Group. Synthesis and Alkylation of Phenol
Authors: Yuan Xingdong , Lee Hyung Ik , Kim Jin Won , Yie Jae Eui , Kim Ji Man 
Published: June 2003

Abstract
Periodic mesoporous organosilicas have been successfully functionalized with sulfonic acid groups. The resulting materials exhibit much higher catalytic activity than ZSM-5 zeolite and higher catalytic stability than MCM-41 functionalized with the same group.
Effective Recovery of Nd–Fe–B Sintered Magnet Scrap Powders as Microwave Absorbing Materials
Authors: Machida Ken-ichi , Masuda Masahiro , Itoh Masahiro , Horikawa Takashi 
Published: June 2003

Abstract
Effective recovery processes for the Nd–Fe–B sintered magnet scrap (sludge) powders as α-Fe/Nd2O3 nanocomposite magnetic particles were established, so that the resin-bonded sheets produced from them showed good microwave absorption properties over a range of 4–8 GHz.
Synthesis, Characterization, and Oxidation Catalysis of a Novel Dawson Polyoxometalate-supported Platinum(II) Complex, [{Pt(cod)}(P2W15V3O62)]7− (cod = 1,5-cyclooctadiene)
Authors: Nomiya Kenji , Torii Hideki , Kato Chika Nozaki , Sado Yuh 
Published: June 2003

Abstract
A novel Dawson polyoxotungstate-based organometallic platinum(II) complex, [{Pt(cod)}(P2W15V3O62)]7− (cod = 1,5-cyclooctadiene), which showed effective catalytic activity for oxidation of cyclohexanol with 30% aqueous hydrogen peroxide, was synthesized and spectroscopically characterized.
Stereospecific Ring-Opening Metathesis Polymerization of endo-Dicyclopentadiene by Schrock–Hoveyda Catalyst and Novel Mo- and W-based Complexes. Development of Crystalline Hydrogenated Poly(endo-dicyclopentadiene)
Authors: Hayano Shigetaka , Kurakata Hiroshi , Uchida Daisuke , Sakamoto Masato , Kishi Naoya , Matsumoto Hirokazu , Tsunogae Yasuo , Igarashi Ichiro 
Published: June 2003

Abstract
Novel crystalline polymer, crystalline hydrogenated poly(endo-dicyclopentadiene), was developed on the basis of the development of new cis- and iso-specific ROMP catalysts such as MoO(rac-5,5′,6,6′-Me4-3,3′-t-Bu2-2,2′-biphenolate)2.
Are uniform assessments for generic advertising optimal if products are differentiated?
Authors: Crespi John M. , Marette Stéphan 
Published: June 2003

AbstractAn analytical framework where consumers display preferences for various qualities of an agricultural commodity is used to investigate the producer welfare effects of generic advertising assessments. Depending upon the degree of differentiation present in the final goods, some producers are shown to benefit more than others from the use of a uniform, per‐unit assessment on all producers. This article delineates those cases where producer assessments should be equal and where assessments should be different to insure an equitable benefit. [EconLit citations: Q130, L110]. © 2003 Wiley Periodicals, Inc. Agribusiness 19: 367–377, 2003.