bluuebunny/crossref_metadata_2025_split huggingface dataset:
The associations of blood volatile organic compounds with sleep health in the American adults: Data from NHANES 2007-2012
Authors: Chen Ming , Tang Mo , He Yi , Pang Ying , Tang Lili 
Published: October 2023

Abstract
Background
Unhealthy sleep health has become a rising public health epidemic, and environmental issues have become a burgeoning orientation to probe into the factors affecting sleep health. Volatile organic compounds (VOCs), common organic pollutants in the air, were connected with some somatic diseases, while whether VOCs exposure or which VOCs lead to sleep abnormality was yet explored so far.
Methods
We analyzed blood content data of five VOCs (LBXVBF, blood bromoform; LBXVBM, blood bromodichloromethane; LBXVCF, blood chloroform; LBXVCM, blood dibromochloromethane; LBXVME, blood MTBE) reported for 5740 adults in NHANES 2007–2012. Sleep health categories, including trouble sleeping, sleep disorder, and insufficient (<6 h/day) or excessive (>9 h/day) sleep, were examined. Weighted multiple linear/logistic regression models were constructed to estimate the linear associations of VOCs exposure with sleep health. As for survival analysis of different VOCs related with individual survival outcomes, we selected the weighted multivariate COX regression model to assess. To explore the non-linear association between variables, restricted cubic spline (RCS) regression analysis was carried out. Moreover, three adjustment regression modeling strategies were utilized to evaluate the VOCs effect on sleep health.
Results
According to the adjusted linear RCS regression model, it is reported that the U-shaped nonlinear relationship between blood VOCs (LBXVBM: P-overall = 0.0284; LBXVCM: P-overall = 0.0321) and sleep duration. The fully adjusted logistic RCS model revealed that LBXVBM, LBXVCM and LBXVCF all displayed statistically significant U-shaped curves in trouble sleep and insufficient sleep groups (P-overall < 0.05). The adjusted COX-RCS analysis results revealed that the LBXVME (p-overall = 0.0359) was risk factor for all-cause mortality.
Conclusions
There was a negative non-linear association between specific blood VOCs and sleep health among U.S. adults, and this adverse effect was mainly manifested in trouble sleeping and prolonged sleep duration. Moreover, the results of survival analysis showed that environmental VOCs exposure could induce adverse survival outcomes. Future prospective longitudinal studies should be conducted to further investigate and determine the degree of the association between VOCs and sleep health.
A study on the impact of life meaning on occupational identity of nursing students in China:A cross-sectional study
Authors: Qiu Lingjing , Miao Qunfang , Zhao YueYan , Zhu Li , Wang Yanling 
Published: October 2023

Abstract
Background
With the alterations of the Chinese epidemic prevention policy, China experienced a nationwide wave of the Coronavirus disease 2019 (COVID-19) pandemic from December 2022 to January 2023.The impact of the COVID-19 pandemic extends beyond individual perceptions of the meaning of life and attitudes toward life and death; it also affects the professional identity of nursing students.This study explored nursing students' professional identity and life meaning of affected by the pandemic.
Methods
An online survey was conducted using the Chinese version of the Nursing Student Career Identity Scale and the Chinese version of the Meaning in Life Questionnaire to assess the current status of nursing students' professional identity and sense of life meaning. Data were also collected on participant gender, education, clinical practice experience, and COVID-19 infection.
Results
The scores for nursing students' sense of professional identity (61.58±16.16) and sense of life meaning (45.29±12.65) were both at an intermediate level. Compared to the scores before the COVID-19 pandemic, Chinese nursing students' professional identity scores increased, while their sense of life meaning scores decreased. Moreover, we found a positive correlation between professional identity and sense of life meaning (p<0.001); nursing students exhibited a stronger professional identity when they had a relatively higher sense of life meaning than those with a relatively lower sense of life meaning.
Conclusion
Enhancing nursing students' sense of meaning in life is crucial for maintaining their professional identity. Attention should be given to life education for nursing students and the development of relevant educational curricula.
Development of Communication Systems for a Photovoltaic Plant with Battery Energy Storage System and All-Sky Camera
Authors: Haas Lucas , Gehrke Camila Seibel , de Lucena Micael Praxedes , Santos Julia Alves , Cavalcante Sidnéia Lira , Hartmann Lucas Vinícius , Gomes Flávio da Silva Vitorino , Silva Italo Roger Ferreira Moreno Pinheiro da 
Published: October 2023

Abstract
The efficient operation, monitoring, and maintenance of a photovoltaic (PV) plant are intrinsically linked to data accessibility and reliability, which, in turn, rely on the robustness of the communication system. As new technologies arise and newer equipment is integrated into the PV plants, such as the battery energy storage system (BESS) that transform the PV plant into a dispatchable plant and the all-sky camera (ASC) that enables the prediction of shading events, the communication system faces new challenges, that are described in this work. In this paper, two communication systems were developed using only open-source software, in which the first was designed for seamless communication between the PV and BESS equipment, while the second was tailored to collect photos from ASC devices. The requirements of the communication systems were defined based on the applications that control the PV plant, and on the industry-standard IEC-61724-1 norm for PV data. After being developed, the communication systems were installed in a PV plant, and the interaction between the data obtained from these two systems is discussed and presented.
Identification of a pyroptosis-immune-related lncRNA signature for prognostic and immune landscape prediction in bladder cancer patients
Authors: Zhao Fuguang , Jia Zhibo , Xie Hui 
Published: October 2023

Abstract

Purpose
Individualized medicine has become increasingly important in bladder cancer treatment, whereas useful biomarkers for prognostic prediction are still lacking. The current study, therefore, constructed a novel risk model based on pyroptosis- and immune-related long noncoding RNAs (Pyro-Imm lncRNAs) to evaluate the potential prognosis of bladder cancer.
Methods
Corresponding data of bladder cancer patients were downloaded from the Cancer Genome Atlas (TCGA) database. The univariate Cox regression analysis, least absolute shrinkage and selection operator (LASSO) regression analysis, and multivariate Cox regression analysis were employed to establish a predictive signature, which was evaluated by receiver operator characteristic (ROC) analysis and Kaplan–Meier analysis. Furthermore, the immune infiltration, immune checkpoints, and responses to chemotherapeutic drugs were analyzed with this model.
Results
Three Pyro-Imm lncRNAs (MAFG-DT, AC024060.1, AC116914.2) were finally identified. Patients in the low-risk group demonstrated a significant survival advantage. The area under the ROC curve (AUC) at 1, 3, and 5 years was 0.694, 0.709, and 0.736 respectively in the entire cohort. KEGG and GO analyses showed that the Wnt pathway plays a crucial role in the high-risk group. The risk score was significantly related to the degree of infiltration of different immune cells, the expression of multiple immune checkpoint genes, and the sensitivity of various chemotherapeutic drugs.
Conclusion
This novel signature provides a theoretical basis for cancer immunology and chemotherapy, which might help develop individualized therapy.
Impact of ablation heat sink effect on the lesion range after liver MWA at different times and powers
Authors: He Ping , Tang Xiao-Qing , Yang You , Luo Xia , Yang Xin , Li Yang , Yu Jin-Hong 
Published: October 2023

Abstract
Background During microwave ablation (MWA) treatment, the heat sink effect can cause incomplete ablation. We discussed the influence of the effect by comparing the lesion ranges of in vitro and vivo.Method Twenty rabbits were divided into four groups with MWA power and time set at 20W-1min, 20W-3min, 30W-1min, and 30W-3min. Compare the range of ablation lesions in vivo and in vitro under a microscope.Results The 20W-1min group and the 30W-3min group: there were not differences in the sizes of each diameter line of the lesion in vivo and in vitro (P > 0.05). The 30W-1min group: there were statistically significant differences in the major and minor axis and the area of lesion including edema zone (P < 0.05), while other diameter lines were not statistically significant differences (P > 0.05); The 20W-3min group: showed statistically significant differences in the major and minor axis and the area of coagulation necrosis lesion and lesion including edema zone (P < 0.05), while the size of circular oedema zone was not differences (P > 0.05).Conclusion The heat sink effect becomes more pronounced as the heat increases. However, after exceeding the thermal damage threshold that the tissue can withstand, the influence of the heat sink effect on MWA lesions will gradually weaken.
A linear optimization approach to decision support with CANS data
Authors: Offner David , Warner Dan , Yi Cara , Zhang Wani 
Published: October 2023

Abstract

This research is meant to make a contribution to the field of Communimetric (CMX) algorithms (Lyons, 2004, 2009). This is the science underscoring the behavioral health and child welfare assessment tools such as the Child and Adolescent Needs and Strengths (CANS) assessment, the Adult Needs and Strengths Assessment (ANSA), and the Family Advocacy and Support Tool (FAST), amongst others (https://praedfoundation.org/). These tools are used throughout the US child serving and adult mental health system not only to assure a standardized assessment process, but also to provide real-time Decision Support (DS) to assessors about client treatment planning and disposition. We propose a novel method for developing CMX DS utilizing linear optimization (commonly known also as linear programming (LP) or (mixed) integer linear programming (ILP or MILP)). Using administrative data from Pennsylvania’s Child Medicaid Behavioral Health system, a MILP model is developed to differentiate profiles that benefit from one of two programs in the Pennsylvania child system of care. The programs picked are both for children at risk of out of home placement, but their clinical models are different. There is often debate in the field as to which program is most appropriate for a given family, and thus the MILP model is meant to help facilitate this decision making. We propose both a method for developing a MILP model in Medicaid behavioral health, as well as a method for testing and validating the model. We then propose a method for identifying the impact on care that utilization of the model could have in facilitating improved care matching in a system. We close with a discussion of how this information could also be used for system planning, and program development issues.
CCCP ameliorated TGF-β1 mediated epithelial-mesenchymal transition in pulmonary fibrosis through the upregulation of PINK1/Parkin-mediated mitophagy
Authors: Ding Gaofeng , Duan Qingke , Wang Wen , Yuan Junhui , Xu Wencai , Lu Yufei 
Published: October 2023

Abstract
In recent years, mitophagy has been proved to be involved in the development of IPF. Nevertheless, the role of PINK1/Parkin-dependent mitophagy in airway epithelial cell injury during the development of IPF has not been sufficiently clarified. Herein, we investigated the effects of PINK1/Parkin-dependent mitophagy and mitochondrial function-regulated epithelial-mesenchymal transaction (EMT) in airway epithelial A549 cells exposed to transforming growth factor-β1 (TGF-β1). TGF-β1 seriously decreased PINK1, Parkin and Beclin‐1protein expression levels and increased the P62 protein expression level, and thus suppressing mitophagy in A549 cells. Meanwhile, the expression levels of E-cadherin and CK19 significantly increased and the N-cadherin and vimentin expression levels decreased with increasing TGF-β1 doses, which further aggravated the EMT phenomenon. Furthermore, transmission electron microscope showed that the numbers of autophagosomes and autophagolysosomes were markedly decreased. Meanwhile, Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), the agonist of PINK1, enhanced the PINK1, Parkin and Beclin‐1protein expression and decreased the P62 protein expression. Confocal microscopy analysis also revealed that CCCP notably enhanced the LC3 protein expression and decreased the FN1 protein expression. CCCP also markedly decrease the ROS level. The expression levels of E-cadherin and CK19 increased and the expression levels of N-cadherin and vimentin decreased after treatment with CCCP. In conclusion, our study confirmed that the PINK1/Parkin-dependent mitophagy deficiency promotes alveolar epithelial cell EMT induced by TGF-β1 and may be involved in the pathogenesis of IPF. CCCP attenuated on TGF-β-induced cell mitophagy and EMT. These findings provide a new experimental basis and target for the treatment of IPF.
Efficient schemes of classifiers for Remote Sensing Satellite Imageries of land use pattern classifications
Authors: Udupi Sachidananda , HC Hemamalini , Kumar Vineet , Chittora Vaibhav , D.K.Prabhuraj  , Patil S.S. 
Published: October 2023

Abstract
Land use pattern classification of remote sensing imagery data is imperative to research that is used in remote sensing applications. Remote sensing (RS) technologies were exploited to mine some of the significant spatially variable factors, such as land cover and land use (LCLU), from satellite images of remote arid areas in Karnataka, India. Four diverse classification techniques, unsupervised and supervised (Maximum likelihood, Mahalanobis Distance, and Minimum Distance) are applied in Bellary district in Karnataka, India for the classification of raw satellite images. The developed maps are then visually compared with each other and accuracy evaluations made using ground-truths are carried out. It was found that the Maximum likelihood technique gave the finest results and both Minimum distance and Mahalanobis distance methods overvalued agricultural land areas. In spite of missing a few insignificant features due to the low resolution of the satellite images, a high-quality accord between parameters extracted automatically from the developed maps and field observations was found.
Assessing the Need for Values Counselling Among Higher Education Students in India: a Survey Study
Authors: SWARGIARY KHRITISH 
Published: October 2023

Abstract
This survey study aims to assess the need for values counselling among higher education students in India. The study aims to examine the impact of counselling interventions on students' values, attitudes, and behaviors. By understanding the potential benefits of values counselling, educators and policymakers can design effective intervention programs to promote holistic development among Indian higher education students.
The new mineral cuprozheshengite, Pb4CuZn2(AsO4)2(PO4)2(OH)2, from Yunnan, China, with site-selective As-P substitution
Authors: Sun Ningyue , Grey Ian E. , Li Guowu , Rewitzer Christian , Xue Yuan , Mumme William G. , Shen Hongtao , Hao Jinhua , MacRae Colin M. , Riboldi-Tunnicliffe Alan , Boer Stephanie , Williams Tim , Kampf Anthony R. 
Published: October 2023

Abstract
Cuprozheshengite, Pb4CuZn2(AsO4)2(PO4)2(OH)2, is a new mineral species from Yunnan, China. It occurs as sub-millimeter greenish-blue hemispherical aggregates of microscopic blade-like crystals on hemimorphite and is closely associated with veszelyite and galena. Cuprozheshengite is brittle with irregular fracture and has a Mohs hardness of 2½–3 and perfect cleavages on {011}. The calculated density is 5.91 g/cm3. The empirical chemical formula of the holotype is (Pb3.97Na0.04Ca0.01)Σ4.02Cu1.06 Zn2.09(AsO4)2[(P0.84As0.12Si0.01)Σ0.97O4]2(OH)2 based on 18 O atoms per formula unit. Cuprozheshengite is triclinic, space group P1, with unit-cell parameters a = 4.7977(8), b = 8.5789(8), c = 10.3855(9) Å, α = 97.270(8)°, β = 101.902(12)°, γ = 91.495(11)°, V = 414.30(9) Å3, and Z = 1. Cuprozheshengite is a member of dongchuanite group, whose general formula is A4VIBIVB2(X1O4)2(X2O4)2(OH)2, where A is an interlayer cation with Pb being dominant; B are transition metals with two crystallographic positions, IVB has tetrahedral coordination and is fully occupied by Zn, while VIB has octahedral coordination and is dominated by Zn or Cu; X1 and X2 are cations with tetrahedral coordination, occupied by As and P. Like other dongchuanite group minerals, the structural framework of cuprozheshengite is composed of two heteropolyhedral columns along [100]. Type 1 columns comprise corner-linked [IVBO4] and [X2O4] tetrahedra. Each tetrahedron is connected with three other tetrahedra in the columns. Type 2 columns have alternating [VIBO4(OH)2] octahedra with pairs of corner-connected [X1O4] tetrahedra. These two columns are connected by corner-sharing between [IVBO4] and [X1O4] tetrahedra to form layers parallel to (011). Pb atoms occupy two independent sites between the layers. Cuprozheshengite is named as the copper analog of zheshengite. Single-crystal X-ray diffraction reveals that As and P order over the X1 and X2 sites, with As tending to occupy X1. Density functional theory (DFT) calculations confirm the occupancy propensity of As benefiting structural stability. The structural and stability studies of cuprozheshengite may have implications for local environmental governance. As a stable mineral in the water and elemental cycles after weathering, cuprozheshengite still has the potential to continually crystallize, fixing As into a stable crystalline waste form.
Modeling of water table profile variations owing to stream–aquifer interaction
Authors: Upadhyaya Ashutosh , Kankarej Manisha M. , Jeet Pawan 
Published: October 2023

Abstract
Spatial and temporal variations of the water table could be explained by the one-dimensional Boussinesq equation by incorporating the variables of evapotranspiration and groundwater recharge with appropriate initial and boundary conditions. In this study, the stream–aquifer interaction has been investigated through a numerical example model with the implementations of Galerkin's method-based Finite Element Solution (FES), Hybrid Finite Analytic Solution (HFAS), Fully Implicit Finite Difference Solution (FIFDS) of one-dimensional nonlinear Boussinesq equation, and analytical solutions of the Boussinesq equation linearized by Baumann's transformation (AS I) as well as linearized by Werner's transformation (AS II). Considering HFAS as the benchmark solution, it was observed that in both recharging and discharging aquifers, water table profiles at 1 day and 5 days as obtained from FES followed by FIFDS were observed quite close to HFAS. Based on L2 and Tchebycheff norms, FES and FIFDS were ranked in first and second place, respectively. L2 and Tchebycheff norms could not consistently establish the performance ranking of analytical solutions but their performance ranking was certainly below the numerical solutions. The performance ranking of analytical solutions could not consistently be established using the L2 and Tchebycheff norms, but it was certainly below the numerical solutions.
The Effects of Statin Therapy on Circulating Levels of
Trimethylamine N-oxide: A Systematic Review and Meta-analysis
Authors: Jamialahmadi Tannaz , Reiner Željko , Matbou Riahi Maryam , Kesharwani Prashant , Eid Ali H. , Tayarani-Najaran Zahra , Sahebkar Amirhossein 
Published: October 2023

Background:
Gut microbiota is associated with an increased risk of atherosclerotic
cardiovascular disease (ASCVD) through the metabolites, which can induce
atherogenesis. One of these metabolites is trimethylamine N-oxide (TMAO). Some
studies indicate that statins do not only decrease LDL-cholesterol and thus ASCVD risk,
but they also affect gut microbiota. There are only a few studies on humans suggesting
that statins might also decrease TMAO, but their results are not unanimous. This
meta-analysis aimed to provide an answer as to whether statins do affect decreasing the
plasma levels of atherogenic TMAO.

Methods:
A systematic literature search in PubMed, Scopus, Embase, and Web of Science
was performed from inception to January 1st, 2023. To assess the quality of each
study included in the meta-analysis, the Cochrane Quality Assessment tool 1 (ROB 1)
was used. Comprehensive Meta-Analysis V3 software was used to perform the metaanalysis.
The weighted mean difference was also used. A random effects meta-analysis
was used to calculate the overall estimate of effect size. In the leave-one-out approach,
one study was excluded from each analysis to evaluate the effect of each study on the
overall effect size.

Results:
Random-effects meta-analysis of 3 studies including 244 patients demonstrated
a significant decrease in plasma TMAO levels after statin treatment (WMD: -1.839,
95% CI: -2.391, -1.287, p<0.001; I2:0). The reduction in TMAO was robust in the leaveone-
out sensitivity analysis.

Conclusion:
Statins might reduce TMAO levels, but there is a need for further evidence
from long-term studies taking into account different types and doses of statins.
Effects of Consuming Repeatedly Heated Edible Oils on Cardiovascular Diseases: A Narrative Review
Authors: Soundararajan Prathyusha , Parthasarathy Srividya , Sakthivelu Meenakumari , Karuppiah Kanchana Mala , Velusamy Palaniyandi , Gopinath Subash Chandra Bose , Raman Pachaiappan 
Published: October 2023

:
Edible oils are inevitable requisites in the human diet as they are enriched with
essential fatty acids, vitamins, carotenoids, sterols, and other antioxidants. Due to their nutritive
value and commercial significance, edible oils have been used for food preparation for
many centuries. The use of global consumption of edible oils has dramatically increased
throughout the world in the 21st century owing to their incredible application in all kinds of
food preparation. However, a variety of pollutants, such as pesticides, toxic chemicals,
heavy metals, and environmental pollution, have contributed to the contamination of edible
oils. Furthermore, the benzophenanthridine alkaloids, sanguinarine, dihydrosanguinarine,
butter yellow, and other several agents are added intentionally, which are known to cause a
number of human diseases. Apart from this, repeated heating and reusing of oils results in
trans fats, and lipid peroxidation alters the fatty acid composition, which adversely affects
the health of consumers and increases the risk of cardiovascular diseases. Moreover, the
prevention of edible oil contamination in human health at various levels is inevitable to ensure
consumer safety. Hence, the present review provides an overview of vegetable cooking
oils and the health ailments that detection techniques are focused on.