bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ultraviolet irradiation effect on characteristics of protease enzyme from African catfish (Clarias sp.) intestines
Authors: Tamaya A , Suwanto A , Hernawan  , Anwar M , Poeloengasih C D , Juligani B , Apriyana W , Fauzi A , Yuliyanto P , Suryani R , Khasanah Y , Syarifah S M , Prasetyo D J 
Published: December 2023

Abstract
The goal of this study was to investigate the impact of UV-C irradiation on the activity of crude enzymes derived from African Catfish intestines as well the optimum conditions for subsequent autolysis processes. Three key variables were assessed: UV-C exposure time, pH and temperature. The experiments involved the homogenization of intestines in cold distilled water followed by subjecting the mixture into UV-C treatment for exposure times of 0, 10, 20 and 30 minutes. After centrifugation process, the collected supernatant was utilized as the crude enzyme. At various level of temperature (40, 50, 60°C) and pH (6, 7, 8) the activity of crude enzyme was assayed with casein as substrate. The findings revealed the increasing of EA as the UV-C exposure time decreased and pH increased, while the highest EA value was observed at temperature of 50°C. Consequently, the optimal conditions were identified as follows: 0 minutes of UV-C exposure time, pH of 8, and temperature of 50°C. Furthermore, UV-Vis absorption, FTIR, and fluorescence spectroscopy of the crude enzyme after UV-C irradiation induction was studied to investigate the its conformational changes. These additional analyses provided valuable insights into the structural alterations of the crude enzyme caused by the UV-C treatment.
Effect of Adding Egg White Powder on Surimi Quality Based on Pangasius and Catfish Flesh
Authors: Rahma A N F , Ustadi  
Published: December 2023

Abstract
The variety of raw materials from demersal fish in small quantities has resulted in the development of freshwater fish-based surimi processing technology. This study aims to determine the best concentration of egg white powder based on pangasius and catfish on the quality of surimi by physically, chemically, and sensory. The experimental design used was a Completely Randomized Design (CRD) with the addition of egg white powder at concentrations of 0%, 1%, 2%, 3%, and 4%. The surimi quality characteristics tested in this study included texture profile, degree of whiteness, pH, moisture, ash, protein, fat, water holding capacity, sensory and folding tests. The results showed a significant effect (P < 0.05) on whiteness, fat, water holding capacity, texture profile, folding and sensory tests. However, it did not affect (P > 0.05) on ash, protein, and pH. The results showed that the concentration of 1% egg white powder was able to improve surimi gel based on quality.
Cinnamon and amylum mucilage alter the physicochemical, sensory, and antioxidant activity of Arthrospira platensis granules
Authors: Elmaghriba A W , Candraningsih M D , Ekantari N 
Published: December 2023

Abstract
This study was done to find out how creating Arthrospira platensis granules using the wet granulation method and a blend of cinnamon powder and amylum mucilage affected their physical, physicochemical, and antioxidant properties. Arthrospira platensis is granulated by the wet granulation method using cinnamon, amylum mucilage, and stevia sugar as sweeteners. The 3×3 factorial design was used, with factors for amylum mucilage of 2.5%, 5%, and 7.5% w/w and cinnamon powder of 0.5%, 1%, and 1.5% w/w. Granules were tested for their physical characteristics (moisture content and pH), physicochemical characteristics (water holding capacity, oil holding capacity, solubility, foam ability, emulsion activity, and stability), and antioxidant activity using the DPPH-RSA and FRAP procedures. The results demonstrated that all granules had moisture contents that met the required standard of less than 7%. Arthrospira platensis dry biomass can be processed into granules, which can raise the OHC but reduce the WHC, solubility, foam ability, emulsion activity, emulsion stability, and antioxidant ability. Amylum mucilage affected the solubility of Arthrospira platensis granules, while cinnamon powder had an impact on the pH level, solubility, and activity of the emulsion. Consumer preferences and buying intention of granules are higher than dry biomass Arthrospira platensis. The combination of 1.5% cinnamon powder and 5% amylum mucilage is the optimal treatment based on pH, solubility, and emulsion activity, making it appropriate for fortified in food product.
Review on shear thickening fluid and its applications in vibration reduction
Authors: Yan Yangyi , Wei Minghai , Huang Zhiping 
Published: December 2023

Abstract
Shear thickening fluid (STF) is a nano-smart material that exhibits an instantaneous increase in viscosity when subjected to specific external loads. Notably, its viscosity response does not necessitate external energy input, making it widely applicable in vibration control, energy absorption, and vibration reduction. This paper first presents an introduction and analogy to the evolution of the thickening mechanism of STF. It then discusses factors that influence the rheological properties of STF, including the dispersed phase, dispersion medium, additives, and external environment. Furthermore, it explores various calculation models of STF in engineering applications, considering their advantages, disadvantages, and applicability. The paper later reviews the progress of STF utilization in vibration reduction and energy consumption, specifically focusing on improving mechanical properties in STF sandwich panels. Finally, it delves into the feasibility of STF application in vibration control by detailing the dynamic mechanical properties and applicability of vibration reduction equipment and calculation models based on STF.
Delicate control of graphite flakes alignment in the copper matrices via powder selections and filling processes
Authors: Zheng Dong , Huang Zhonghua , Shen Zhengyan , Wu Renjun , Khanlari Khashayar , Ji Gang , Silvain Jean-François 
Published: December 2023

Abstract
Due to the anisotropy properties of graphite flakes (Gf), the control of their orientation inside copper (Cu) matrice is strictly correlated with the final properties of such metal matrix composite (MMC). In this study, MMCs are fabricated by powder metallurgy process using three types of Cu powder particles (flake, dendritic, and spherical) as well as different powder filling methods. By using Cu flake powder with a relatively lower apparent density as compared to the two other Cu powder types (dendritic and spherical), high aligned Gf could be easily obtained, after uniaxial hot pressing, in a one-step powder filling approach. For the other two types of powders, a comparable orientation degree of Gf could be achieved only via several steps of delicate powder pressing. In-plane thermal conductivities of Cu/Gf composites were enhanced by improving the orientation degree of Gf, agreeing with effective medium approximation predictions (Maximum TC up to 540 W mK−1). A modeling, based on the apparent density of Cu powders, was discussed to show the effect of the alignment process on the final thermal property of such MMCs. This model supplies a basic guideline to obtain highly orientated Gf.
Sol-gel CdS layer for TiO2 nanorod-based quantum dots-sensitized solar cells
Authors: Chen Shixin , Meng Yangqi , Feng Shuang , Ou Tianji 
Published: December 2023

Abstract
The CdS layer was essential for CdSe quantum dot-sensitized solar cells (QDSSCs) as the seed layer and energy barrier. Here, a novel sol–gel method was employed to prepare the CdS interlayer (SG-CdS) for TiO2 nanorod-based QDSSCs. Due to the sufficient reaction of the Cd and S sources in the sol–gel solution, SG-CdS exhibited fewer impurities than CdS produced by commonly used chemical bath deposition (CBD-CdS). QDSSCs with SG-CdS exhibited an open-circuit voltage of 490 mV, a short-circuit current density of 14.12 mA cm−2, and a fill factor of 0.35. The power conversion efficiency of the QDSSCs with SG-CdS was 2.48%, which was higher than that of the QDSSCs with CBD-CdS (2.02%). Moreover, electrochemical impedance spectroscopy showed that the QDSSCs with SG-CdS yielded a charge recombination resistance of 99.92 Ω at a bias voltage of −0.5 V, demonstrating less charge recombination than the QDSSCs with CBD-CdS (82.16 Ω). Therefore, the performance of the CdSe QDSSCs could be improved by reducing the impurities in CdS. This study revealed the advantages of SG-CdS in replacing CBD-CdS as the interlayer for charge transport, as well as good applicability with nanorod photoanodes in QDSSCs.
Three-dimensional analysis of vortex-lattice formation in rotating Bose–Einstein condensates using smoothed-particle hydrodynamics
Authors: Tsuzuki Satori , Itoh Eri , Nishinari Katsuhiro 
Published: December 2023

Abstract
Recently, we presented a new numerical scheme for vortex lattice formation in a rotating Bose–Einstein condensate (BEC) using smoothed particle hydrodynamics (SPH) with an explicit time-integrating scheme; our SPH scheme could reproduce the vortex lattices and their formation processes in rotating quasi-two-dimensional (2D) BECs trapped in a 2D harmonic potential. In this study, we have successfully demonstrated a simulation of rotating 3D BECs trapped in a 3D harmonic potential forming ‘cigar-shaped’ condensates. We have found that our scheme can reproduce the following typical behaviors of rotating 3D BECs observed in the literature: (i) the characteristic shape of the lattice formed in the cross-section at the origin and its formation process, (ii) the stable existence of vortex lines along the vertical axis after reaching the steady state, (iii) a ‘cookie-cutter’ shape, with a similar lattice shape observed wherever we cut the condensate in a certain range in the vertical direction, (iv) the bending of vortex lines when approaching the inner edges of the condensate, and (v) the formation of vortex lattices by vortices entering from outside the condensate. Therefore, we further validated our scheme by simulating rotating 3D BECs.
The world was their laboratory: how two pioneer scientist-administrators, James Watt and Zdenek Fejfar, advanced methods and international collaboration in cardiovascular disease epidemiology during the Cold War
Authors: Blackburn Henry , Oppenheimer Gerald 
Published: December 2023

Abstract
In 1952, James Watt, a young US Public Health Service (PHS) infectious disease epidemiologist, was appointed—amid wide surprise—director of the US National Heart Institute (NHI) where he served until 1961. He skillfully advanced epidemiologic research methods and study conduct nationally while also establishing epidemiology in the administrative hierarchy of the institute. Watt soon turned to development of an effective program in international cardiovascular disease (CVD) epidemiology under auspices of the World Health Organization (WHO) at the United Nations in Geneva. That effort resulted in the 1959 appointment of Zdenek Fejfar, a young Czech clinical investigator, as director of the WHO CVD Unit. The coming together of Watt and Fejfar, with a joint focus on improved methods and population comparisons, helped establish a vigorous international community of CVD epidemiology. Their collaboration and friendship remained active and close throughout their career assignments and thereafter, as documented in this story.
An exploratory mixed-methods evaluation of continuing education opportunities related to the care of sexual and gender minority patients from ACPE-accredited providers
Authors: A. Nardolillo Joseph , DiLucia Alex , Kerwin Taya , Ramirez Samantha R , Vazquez Maria C , Murry Logan T , Medlin Christopher G 
Published: December 2023

Abstract

Purpose
The objective of this analysis was to describe trends in continuing education opportunities for pharmacy professionals across the US related to the care of sexual and gender minority (SGM) patients.

Methods
Continuing education programs offered by Accreditation Council for Pharmacy Education (ACPE)–accredited providers from 2012 through 2022 were identified by searching the ACPE database for titles containing SGM terminology. Data including ACPE provider classification, activity type, format, audience, ACPE topic designator, interprofessional accreditation, contact hours, and learning objectives were collected. Content analysis was used to categorize activities.

Results
Following removal of duplicates and non–SGM-focused programming, 726 programs were identified. The most commonly observed program characteristics included a live format (67.6%, n = 491), a pharmacist audience (77.1%, n = 560), knowledge-based activities (90.8%, n = 656), a college or school of pharmacy provider (21.6%, n = 157), an ACPE topic of pharmacy administration (50.6%, n = 367), and a focus on pharmacy rather than interprofessional audiences (87.1%, n = 632). The median program length was 1 hour (interquartile range, 1-1.25 hours). The qualitative analysis identified programs focused on topics of gender-affirming care (pharmacotherapy) (32.1%, n = 233), general SGM (26.7%, n = 194), gender-affirming care (nonpharmacotherapy), sexually transmitted infections (7.2%, n = 52), and health disparities (3.9%, n = 28).

Conclusion
Advancement has occurred in the number of available continuing pharmacy education programs focused on the care of SGM patients. Further information regarding specific content and effectiveness of continuing education is necessary to determine strategies to better prepare pharmacy professionals to care for this growing patient population.
The links between wood traits and species demography change during tree development in a lowland tropical rainforest
Authors: González-Melo Andrés , Posada Juan Manuel , Beauchêne Jacques , Lehnebach Romain , Levionnois Sébastian , Derroire Géraldine , Clair Bruno 
Published: December 2023

Abstract
One foundational assumption of trait-based ecology is that traits can predict species demography. However, the links between traits and demographic rates are, in general, not as strong as expected. These weak associations may be due to the use of traits that are distantly related to performance, and/or the lack of consideration of size-related variations in both traits and demographic rates. Here, we examined how wood traits were related to demographic rates in 19 tree species from a lowland forest in eastern Amazonia. We measured 11 wood traits (i.e. structural, anatomical and chemical traits) in sapling, juvenile and adult wood; and related them to growth and mortality rates (MR) at different ontogenetic stages. The links between wood traits and demographic rates changed during tree development. At the sapling stage, relative growth rates (RGR) were negatively related to wood specific gravity (WSG) and total parenchyma fractions, while MR decreased with radial parenchyma fractions, but increased with vessel lumen area (VA). Juvenile RGR were unrelated to wood traits, whereas juvenile MR were negatively related to WSG and axial parenchyma fractions. At the adult stage, RGR scaled with VA and wood potassium concentrations. Adult MR were not predicted by any trait. Overall, the strength of the trait-demography associations decreased at later ontogenetic stages. Our results indicate that the associations between traits and demographic rates can change as trees age. Also, wood chemical or anatomical traits may be better predictors of growth and MR than WSG. Our findings are important to expand our knowledge on tree life-history variations and community dynamics in tropical forests, by broadening our understanding on the links between wood traits and demography during tree development.
Comparing the accuracy of prediction models to detect clinically relevant post-hepatectomy liver failure early after major hepatectomy
Authors: Baumgartner Ruth , Engstrand Jennie , Rajala Patric , Grip Jonathan , Ghorbani Poya , Sparrelid Ernesto , Gilg Stefan 
Published: December 2023

Abstract

Background
Arterial lactate measurements were recently suggested as an early predictor of clinically relevant post-hepatectomy liver failure (PHLF). This needed to be evaluated in the subgroup of major hepatectomies only.

Method
This observational cohort study included consecutive elective major hepatectomies at Karolinska University Hospital from 2010 to 2018. Clinical risk factors for PHLF, perioperative arterial lactate measurements and routine lab values were included in uni- and multivariable regression analysis. Receiver operating characteristics and risk cut-offs were calculated.

Results
In total, 649 patients constituted the study cohort, of which 92 developed PHLF grade B/C according to the International Study Group of Liver Surgery (ISGLS). Lactate reached significantly higher intra- and postoperative levels in PHLF grades B and C compared to grade A or no liver failure (all P &lt; 0.002). Lactate on postoperative day (POD) 1 was superior to earlier measurement time points in predicting PHLF B/C (AUC 0.75), but was outperformed by both clinical risk factors (AUC 0.81, P = 0.031) and bilirubin POD1 (AUC 0.83, P = 0.013). A multivariable logistic regression model including clinical risk factors and bilirubin POD1 had the highest AUC of 0.87 (P = 0.006), with 56.6% sensitivity and 94.7% specificity for PHLF grade B/C (cut-off ≥0.32). The model identified 46.7% of patients with 90-day mortality and had an equally good discriminatory potential for mortality as the established ISGLS criteria for PHLF grade B/C but could be applied already on POD1.

Conclusion
The potential of lactate to predict PHLF following major hepatectomy was inferior to a prediction model consisting of clinical risk factors and bilirubin on first post-operative day.
Empowering emerging leaders: a model public planning academy
Authors: Mandarano Lynn A 
Published: December 2023

Abstract
Public planning academies are a form of community leadership development programming utilized by cities to increase community engagement. This article presents a case study of the Citizens Planning Institute in Philadelphia, in the US state of Pennsylvania, and documents the program’s outcomes using the Community Capitals Framework. The results highlight the capacities developed by participants and their community engagement post program. The findings contribute to understanding how public planning academies support emerging leaders with new knowledge and skills, and enhanced leadership traits (human capital) as well as social, political, and cultural capitals that enhance engagement.
DrugGen: a database of de novo-generated molecular binders for specified target proteins
Authors: Qian Hao , Zhou Jingyuan , Tu Shikui , Xu Lei 
Published: December 2023

Abstract
De novo molecular generation is a promising approach to drug discovery, building novel molecules from the scratch that can bind the target proteins specifically. With the increasing availability of machine learning algorithms and computational power, artificial intelligence (AI) has emerged as a valuable tool for this purpose. Here, we have developed a database of 3D ligands that collects six AI models for de novo molecular generation based on target proteins, including 20 disease-associated targets. Our database currently includes 1767 protein targets and up to 164 107 de novo-designed molecules. The primary goal is to provide an easily accessible and user-friendly molecular database for professionals in the fields of bioinformatics, pharmacology and related areas, enabling them to efficiently screen for potential lead compounds with biological activity. Additionally, our database provides a comprehensive resource for computational scientists to explore and compare different AI models in terms of their performance in generating novel molecules with desirable properties. All the resources and services are publicly accessible at https://cmach.sjtu.edu.cn/drug/.
Database URL: https://cmach.sjtu.edu.cn/drug/.
Unravelling translanguaging: a critical appraisal
Authors: Treffers-Daller Jeanine 
Published: December 2023

Abstract
The concept of translanguaging is one of the most successful ones in the recent history of multilingualism research. But what does it really mean? It covers such a wide semantic field that users seem to be free to decide its meaning in whatever way they wish. A key uniting idea of the different approaches is that teachers should ‘draw upon’ the first language(s) of learners in language teaching or allow the learners to do so to scaffold the learning process. However, this is by no means novel or controversial. The conceptual vagueness of the term translanguaging invites researchers and practitioners to propose a flurry of operationalisations, and make recommendations for practice for which there is no empirical evidence. The concept and the pedagogical applications fall apart as soon as one digs a little deeper. It is timely to either radically revisit the concept and narrow it down or abandon it altogether.
Code-switching and translanguaging: why they have a lot in common
Authors: Treffers-Daller Jeanine 
Published: December 2023

Abstract
The proponents of translanguaging are often not aware of the history of code-switching research and the relevance of this research for a range of the claims they make, for example on the issue of the separability of systems. While it is understandable that new paradigms try to emphasize how different they are from others, we cannot see why and how a new approach is different from previous ones unless a fair presentation is given of the position of others and detailed evidence is provided of the claims that are being made. In this rebuttal I show that the translanguaging literature owes a lot to the literature on code-switching, and that the translanguaging practices as found in the instructions to teachers look very similar to examples of code-switching as found in the extensive academic literature. In addition, many of the recommendations for pedagogical practice are not as novel as the proponents of translanguaging would like us to believe: many teachers when they hear about translanguaging say that they have been doing it for years but haven’t had a name for it. It is time for the translanguaging papers to now recognize that the translanguaging agenda developed out of the ideas of other excellent researchers in bilingualism.
PBRM-1/PBAF-regulated genes in a multipotent progenitor in Caenorhabditis elegans
Authors: Mathies Laura D , Kim Andrew C , Soukup Evan M , Thomas Alan’da E , Bettinger Jill C 
Published: December 2023

Abstract
The Caenorhabditis elegans somatic gonadal precursors (SGPs) are multipotent progenitors that generate all somatic cells of the adult reproductive system. The 2 SGPs originate in the mesodermal layer and are born through a division that produces one SGP and one head mesodermal cell (hmc). One hmc terminally differentiates, and the other dies by programmed cell death. The polybromo-associated BAF (PBAF) chromatin remodeling complex promotes the multipotent SGP fate. The complete loss of PBAF causes lethality, so we used a combination of Cre/lox recombination and GFP nanobody-directed protein degradation to eliminate PBRM-1, the signature subunit of the PBAF complex, from 83 mesodermal cells, including SGPs, body muscles, and the hmc. We used RNA sequencing to identify genes acting downstream of PBAF in these cells and identified 1,955 transcripts that were significantly differentially expressed between pbrm-1(−) and pbrm-1(+) in the mesoderm of L1 larvae. We found that genes involved in muscle cell function were overrepresented; most of these genes had lower expression in the absence of PBRM-1, suggesting that PBAF promotes muscle differentiation. Among the differentially expressed genes were 125 that are normally expressed at higher levels in SGP vs hmc and positively regulated by pbrm-1 and 53 that are normally expressed at higher levels in hmc vs SGP and are negatively regulated by pbrm-1; these are candidate regulators of the SGP/hmc fate decision. We validated one candidate gene using a fluorescent reporter; the hsp-12.3 reporter was derepressed in SGPs in pbrm-1 mutants, suggesting that hsp-12.3 expression is normally repressed by pbrm-1 in SGPs.