bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations Between Age-Related Hearing Loss, Cognitive Impairment, and Multiple Chronic Conditions in a Group Care Setting
Authors: Mamo Sara K. , Pearlman Jessica , Wheeler Kara A. 
Published: November 2023

Purpose:
The purpose of this study was to explore the relationships between hearing loss, cognitive status, and a range of health outcomes over a period of 2 years in a sample of older adults who are enrolled in Program of All-Inclusive Care for the Elderly, which is a Medicare/Medicaid beneficiary program for individuals who are nursing home eligible but living in the community at time of enrollment.

Method:

The sample (
N
= 144) includes a diverse (47% White/non-Hispanic, 35% Black/African American, and 16% Latin/Hispanic) group of adults ranging from 55 to 93 years old. We used medical chart data to measure respondents' cognitive and health status, including chronic conditions and hospital use. Hearing status was measured once at the beginning of the 2-year review period. We used logistic regression and negative binomial hurdle models for analyses. We used latent class analysis (LCA) to explore the extent to which respondents cluster into a set of “health profiles” characterized by their hearing, cognitive status, and health conditions.

Results:
We found that hearing loss is weakly associated with heart disease and diabetes and associated with cerebrovascular disease and falls; cognitive impairment is also associated with cerebrovascular disease and the number of falls. LCA indicates that respondents cluster into a variety of health profiles with a consistent pairing of hearing loss and depression.

Conclusions:
The results are largely consistent with associations reported in epidemiological studies that include age-related hearing loss. Of particular interest in this study is the LCA that suggested that all of the profiles associated with a high likelihood of hearing loss included a high risk of depression. The co-occurrence of these two factors highlights the need to identify and treat hearing loss in older adults, especially as part of the treatment plan for individuals with depressive symptoms.
Modulating Complex Sentence Processing in Aphasia Through Attention and Semantic Networks
Authors: Baker Carolyn , Love Tracy 
Published: November 2023

Purpose:
Lexical processing impairments such as delayed and reduced activation of lexical-semantic information have been linked to syntactic processing disruptions and sentence comprehension deficits in individuals with aphasia (IWAs). Lexical-level deficits can also preclude successful lexical encoding during sentence processing and amplify the processing costs of similarity-based interference during syntactic retrieval. We investigate whether two manipulations to engage attention and pre-activate semantic features of a target (to-be-retrieved) noun will (a) boost lexical activation during initial lexical encoding and (b) facilitate syntactic dependency linking through improved resolution of interference in IWAs and neurologically unimpaired age-matched controls (AMCs).

Method:
Eye-tracking-while-listening with a visual world paradigm was used to investigate whether semantic and attentional manipulations modulated initial lexical processing and downstream syntactic retrieval of the direct-object noun in object-relative sentences.

Results:
In the attention and semantic manipulations, the AMC group showed no changes in initial lexical access levels; however, gaze patterns revealed clear facilitations in dependency linking and interference resolution. In the IWA group, the attentional cue increased and maintained activation of N1 with modest facilitations in dependency linking. In the semantic condition, IWA results showed a greater degree of facilitation during dependency linking.

Conclusions:
The results suggest that attention and semantic activation are parameters that may be manipulated to strengthen encoding of lexical representations to facilitate retrieval (i.e., dependency linking) and mitigate similarity-based interference. In IWAs, these manipulations may help to reduce lexical processing deficits that can preclude successful encoding.
Inotodiol ameliorates the progression of osteoarthritis: An in
vitro and in vivo study
Authors: Qian Wanfeng , Ji Ruheng , Ye Qiujie , Hu Wenjun , Zhou Linying , Pan Hongwu , Li Xiaoming 
Published: November 2023

AbstractOsteoarthritis is a common chronic degenerative disease, of which the essence is
the degenerative changes of bone and joint cartilage, involving damage in
multiple structures such as bone, synovium and joints. In the mechanism of
arthritis inflammation is closely related, and therefore the exploration to
inhibit inflammatory mediators is crucial for the clinical prevention and
treatment of osteoarthritis. Inotodiol is a lanostane triterpenoid isolated from
Inonotus obliquus, which had been extensively reported to be an
anti-inflammatory agent, but its effect on arthritis remains unknown. In this
study, we firstly demonstrated that inotodiol significantly reduced
IL-1β-induced chondrocyte injury and inhibited the release of
inflammatory factors. At the same time, experiments in vivo showed that
inotodiol could effectively improve the symptoms of joint injury in mice and
reduce the area of cartilage destruction, indicating that inotodiol may be a
potential therapeutic drug for osteoarthritis.
Therapie bei MDR-, prä-XDR-, XDR-Tuberkulose und Rifampicin-Resistenz oder bei Medikamentenunverträglichkeit gegenüber mindestens Rifampicin
Authors: Otto-Knapp Ralf , Bauer Torsten , Brinkmann Folke , Feiterna-Sperling Cornelia , Friesen Inna , Geerdes-Fenge Hilte , Hartmann Pia , Häcker Brit , Hauer Barbara , Haas Walter , Heyckendorf Jan , Kuhns Martin , Lange Christoph , Maurer Florian P. , Nienhaus Albert , Priwitzer Martin , Richter Elvira , Salzer Helmut J. F. , Schoch Otto , Schönfeld Nicolas , Schaberg Tom 
Published: November 2023

ZusammenfassungIm Dezember 2022 hat die Weltgesundheitsorganisation (WHO) die Empfehlungen für die Behandlung der medikamentenresistenten Tuberkulose (TB) aktualisiert. Die Bewertung dieser Empfehlungen und der neuen Studiendaten macht auch für den deutschsprachigen Raum eine Aktualisierung der Leitlinienempfehlungen zur Therapie der mindestens Rifampicin-resistenten Tuberkulose notwendig, welche die entsprechenden Kapitel ersetzt. Auch für Deutschland, Österreich und die Schweiz wird nun eine verkürzte, mindestens 6-monatige MDR-TB-Therapie unter Einsatz der festgelegten und nicht veränderbaren Medikamentenkombination Bedaquilin, Pretomanid, Linezolid und Moxifloxacin (BPaLM) empfohlen, wenn alle hierfür notwendigen Voraussetzungen erfüllt sind. Diese Empfehlung gilt für TB-Fälle mit nachgewiesener Rifampicin-Resistenz einschließlich der Rifampicin-Monoresistenz. Zur Behandlung der präextensiven (prä-XDR) TB wird weiterhin in erster Linie eine individualisierte, an die Resistenzdaten angepasste Therapie über 18 Monate empfohlen. Die nicht veränderbare Medikamentenkombination Bedaquilin, Pretomanid und Linezolid (BPaL) kann bei prä-XDR alternativ angewendet werden, wenn alle Voraussetzungen dafür erfüllt sind. Die notwendigen Voraussetzungen für den Einsatz von BPaLM und BPaL werden in diesem Amendment zur S2k-Leitlinie „Tuberkulose im Erwachsenenalter“ begründet dargestellt.
Advanced Magnetic Resonance Imaging and Molecular Imaging of the Painful Knee
Authors: Mostert Jacob M. , Dur Niels B.J. , Li Xiufeng , Ellermann Jutta M. , Hemke Robert , Hales Laurel , Mazzoli Valentina , Kogan Feliks , Griffith James F. , Oei Edwin H.G. , van der Heijden Rianne A. 
Published: November 2023

AbstractChronic knee pain is a common condition. Causes of knee pain include trauma, inflammation, and degeneration, but in many patients the pathophysiology remains unknown. Recent developments in advanced magnetic resonance imaging (MRI) techniques and molecular imaging facilitate more in-depth research focused on the pathophysiology of chronic musculoskeletal pain and more specifically inflammation. The forthcoming new insights can help develop better targeted treatment, and some imaging techniques may even serve as imaging biomarkers for predicting and assessing treatment response in the future. This review highlights the latest developments in perfusion MRI, diffusion MRI, and molecular imaging with positron emission tomography/MRI and their application in the painful knee. The primary focus is synovial inflammation, also known as synovitis. Bone perfusion and bone metabolism are also addressed.
Diffusion Tensor Imaging of Peripheral Nerves: Current Status and New Developments
Authors: Yoon Daehyun , Lutz Amelie M. 
Published: November 2023

AbstractDiffusion tensor imaging (DTI) is an emerging technique for peripheral nerve imaging that can provide information about the microstructural organization and connectivity of these nerves and complement the information gained from anatomical magnetic resonance imaging (MRI) sequences. With DTI it is possible to reconstruct nerve pathways and visualize the three-dimensional trajectory of nerve fibers, as in nerve tractography. More importantly, DTI allows for quantitative evaluation of peripheral nerves by the calculation of several important parameters that offer insight into the functional status of a nerve. Thus DTI has a high potential to add value to the work-up of peripheral nerve pathologies, although it is more technically demanding. Peripheral nerves pose specific challenges to DTI due to their small diameter and DTI's spatial resolution, contrast, location, and inherent field inhomogeneities when imaging certain anatomical locations. Numerous efforts are underway to resolve these technical challenges and thus enable wider acceptance of DTI in peripheral nerve MRI.
Up-and-coming Radiotracers for Imaging Pain Generators
Authors: van der Heijden Rianne A. , Biswal Sandip 
Published: November 2023

AbstractChronic musculoskeletal pain is among the most highly prevalent diseases worldwide. Managing patients with chronic pain remains very challenging because current imaging techniques focus on morphological causes of pain that can be inaccurate and misleading. Moving away from anatomical constructs of disease, molecular imaging has emerged as a method to identify diseases according to their molecular, physiologic, or cellular signatures that can be applied to the variety of biomolecular changes that occur in nociception and pain processing and therefore have tremendous potential for precisely pinpointing the source of a patient's pain. Several molecular imaging approaches to image the painful process are now available, including imaging of voltage-gated sodium channels, calcium channels, hypermetabolic processes, the substance P receptor, the sigma-1 receptor, and imaging of macrophage trafficking. This article provides an overview of promising molecular imaging approaches for the imaging of musculoskeletal pain with a focus on preclinical methods.
Prevalence and patterns of mental and cognitive impairments among missing older adults in China
Authors: Zhang Zhihai , Zhu Fengxia , Zhang Yueyun 
Published: November 2023

AbstractMissing older adults (MOAs) are older adults whose whereabouts cannot be established at present or at any time previously. The MOAs represent a notable intersection of old age and missingness, given the accelerating population aging and sizable missing persons in many societies. However, the prevalence and patterns of mental and cognitive conditions of MOAs have received little attention. This study aimed to address this gap. This study collected data from the Toutiao Alert, a large missing-person appeal platform in China. The analytical sample included 32885 MOAs (mean age, 73.6 years; female, 40.2%) who were reported missing on the platform between 2017 and 2021. The mental and cognitive impairments and other measures were extracted from the reported information. The results show that the overall levels of mental and cognitive impairments among MOAs were 10.6 and 41.5%, respectively. Moreover, these levels varied by gender, age, and spatiotemporal factors such as the region and year of missingness. Women exhibited higher levels of mental and cognitive impairments. Age was associated with lower levels of mental impairments but higher levels of cognitive impairments. Across regions, MOAs from Northeast China had lower levels of mental and cognitive impairments. From 2017 to 2021, the mental or cognitive impairment levels initially decreased, but then increased until the most recent year. The prevalence and patterns of mental and cognitive impairments revealed in this study contributed to our understanding of the health and well-being of MOAs as one of the distinct groups within the expanding elderly population. Future healthcare policies and services targeting MOAs may benefit from these findings.
Conceptualization ofSar(Head) in Persian figurative expressions
Authors: Ahangari Nahid 
Published: November 2023

AbstractSinceLakoff and Johnson (1999)proposed ‘Embodiment theory’ in Cognitive Linguistics, the relationship between language and body parts has been a subject of research for many years. This paper examines the conceptualization of body part ‘head’ in 305 Persian figurative expressions and proverbs in two related Iranian dictionaries. Using the ‘Cultural Conceptualization’ model introduced bySharifian (2011), this article demonstrates howsar, the Persian equivalent to ‘head’, is conceptualized to convey various notions such as mental activity, emotions, personality traits, social behavior and state, time, place, death, measurement, leader, and success. The conceptualization of body parts in a language can be bounded to that language and often rooted in some cultural background; however, this topic has received scant attention among scholars of Persian language. Apparently, no comprehensive studies on the conceptualization of head in Persian figurative expressions have been conducted so far, thus this research is an attempt to fill this gap. The analysis of the afore-mentioned word revealed that it can convey several meanings; these include mental activity, emotions, human traits, social action and status, time, location, death, measurement, leadership and success. The variety of meanings stems from contexts within which the word is presented.
Crystal structure prediction and non-superconductivity of N-doped LuH3 at near ambient pressure
Authors: Hu Kai , Geng Yixing , Yu Jinqing , Gu Yuqiu 
Published: November 2023

Abstract
Lanthanide polyhydrides, which have attracted the attention of researchers, are considered as a potential candidate material for high-temperature superconductivity. Especially, it is reported that N-doped LuH3 exhibits near ambient superconductivity recently. It has attracted attention to room temperature superconductivity of ternary Lu-N-H systems at near ambient pressure. Here, we constructed a LuNH3 (N-doped LuH3) compound to predict the crystal structural at relatively low pressures. We found a stable ternary LuNH3 structure with a tetragonal P4mm phase under 5 GPa. In addition, our

T
c

calculations show that the P4mm LuNH3 structure does not exhibit superconductivity down to 0.3 K at near ambient pressure due to the H atoms hardly contribute to acoustical phonons.
Length – Weight Relationship of Bivalves and Gastropods from Mangrove Forest of Brgy. Nabago, Surigao City, Philippines
Authors: Degamon Louella S. , Eviota Manny P. , Hugo Rosalia L. , Bertulfo Roselle E. , Odtojan Medielyn M. , Buenaflor Gheleene S. , Cuadrado Jerry T. 
Published: November 2023

AbstractBivalves and gastropods are among the most important food resource in coastal communities. The destructive ways of harvesting these mangrove associate fauna may cause a threat to the forest and may alter the physiological condition of these organisms. The length-weight relationship of two bivalves (Anodontia edentulaandSaccostrea cuccullata) and 11 gastropods (Littoraria angulifera, Littoraria melanostoma, Littoraria scabra, Chicoreus capunicus, Tenguella musiva, Nerita exuvia, Nerita lineata, Cerithidea decollate, Terebralia palustris, andTerebralia sulcata) species collected from the mangrove forest of Barangay Nabago, Surigao City was assessed in this study.A. edentulaexhibits positive allometry (b=3.7002) whileS. cuccullatashows negative allometry (b=2.6145). The 11 gastropod species demonstrate a negative allometric pattern (b<3). The negative allometric pattern of these species indicates that the length increased faster than the weight, which could be attributed to the different environmental factors in the area. The data obtained in this study is essential for the monitoring of these organisms and management of the entire mangrove ecosystem in the area.
The Use of Fly Ash and Bottom Ash to Reduce COD, TSS, and Color in Textile Industry Wastewater Effluent
Authors: Ayuningsih Barqhadini , Yuniarto Adhi , Zuhri Syaifudin 
Published: November 2023

Abstract
The textile industry wastewater effluent contains some levels of COD, TSS, and color, it must be reprocessed as a tertiary treatment using the filtration method. The goal of this research was to examine the ability of fly ash and bottom ash as filtration media to reduce the pollutant / organic load of COD, TSS, and color in textile industry wastewater effluent. The slow sand filter method was used in this study, and the filter media was derived from coal combustion waste. The variation used in this study is a variation of filter media (fly ash and bottom ash), with fly ash diameters of 0.11 and 0.35 mm, bottom ash diameters of 0.85 - 1.50 mm, and media thickness of 1.50 - 2.00 mm (10 cm and 20 cm). The study’s findings demonstrated that using bottom ash and fly ash media in the filtration process with a slow sand filter system could maximize the efficiency of reducing COD, TSS, and color levels in textile industry wastewater effluent. In fly ash media, it can reduce COD, TSS, and Color by 90.58%, 81.87%, and 100%. Meanwhile, Bottom Ash filter media has an average COD, TSS, and Color reduction of 87.80%, 81.87%, and of 100%.
Subsurface Identification using Resistivity Method for Infrastructure Planning in Benowo Area, Surabaya City
Authors: Utama Widya , Putra Dhea Pratama Novian , Indriani Rista Fitri , Garini Sherly Ardhya 
Published: November 2023

AbstractSubsurface rock identification in infrastructure construction is important to get the information in planning and monitoring the rock carrying capacity and groundwater systems for infrastructure construction. To get the subsurface condition information that are relatively shallow with detailed results, Resistivity method with Wenner configuration is used. Research is in Benowo area, where dominated by pond area. This research used 5 Resistivity lines, which are divided into 2 locations separated by distance of about 2400 meters as Z1 and Z2 areas. For the subsurface resistivity section at Z1 area there are 2 lines, while at Z2 area there are 3 lines. It is known at Z1 area, top layer is topsoil (2.26-33.00 Ωm) and the bottom layer was identified as clay (0.30-2.26 Ωm). At Z2, top layer being topsoil (0.306-0.708 Ωm), followed by clay layer (0.100-0.306 Ωm), and the sand layer (0.231-0.535 Ωm) in the bottom of resistivity model. Groundwater system shows topsoil acts as a vadose zone, clay layer acts as an aquiclude and the sand layer acts as an unconfined aquifer. Saturated water influences the low resistivity value measurement related to the environmental condition dominated by pond area, beside measurements in rainy season are also suspected to be the cause of low resistivity measured. To be applied infrastructure development in the Benowo area need further treatment activity like soil and/or rock pavement to support infrastructure safety. This research result is related to geotechnical aspects like rock coring, pavement, and optimum architectural design can be an alternative for further research.
Submarine landslide-induced tsunami generation in Makassar strait, Indonesia using Non-hydrostatic wave model
Authors: Gumbira G , Wibowo M , Khoirunnisa H , Karima S , Kongko W , Widagdo A B , Rachman R A , Pasma G R , Suharyanto H H R , Lubis M Z 
Published: November 2023

AbstractTsunami modelling of potential landslide-induced tsunami in Makassar Strait is carried out to quantify possible damage to the nearby cities. The numerical model is used to represent the wave generation by using NHWAVE model. The simulations consist of a series of scenarios based on distinct size of the landslide volume. Four landslides with volume 5, 8, 70, and 200 km3 are used as tsunami sources in the initiation stage. The sources are evenly distributed in the strait addressing different landslide location. Maximum wave heights of 1.5 m are found in the area between Palu and Bangkir from case 1 and around Talok from case 2 simulations. The empirical run-up calculation of 7.5 m is estimated at the land for the presented wave height. The value significantly elevates the case 3 and 4 proportional to the volume values. The waves impact more than half of coastline with maximum value found in the Sulawesi side. Interestingly, wide and narrow shelf next to Kalimantan Island plays an important role in reducing the tsunami hazard level.
Protecting the Country from Bio-invasion, a Case Study of Biofouling Management in Indonesia
Authors: Utama I K A P , Hermawan Y A , Ariesta R C , Risdiyanto S , Sitinjak M , Ardhiyanto W 
Published: November 2023

Abstract
The introduction of Invasive Aquatic Species (IAS) to new environments by ships has been identified as a major threat to world’s oceans and the conservation of biodiversity. The International Maritime Organization (IMO) has international efforts to tackle IAS by taking the transfer of non-indigenous organisms through shipping. In response to global oncerns about risks associated with ship-borne biofouling, the GEF-UNDP-IMO GloFouling Partnerships Project (GFP) was launched, involving several Lead Partnering Countries (LPC) to conduct national rapid status assessment concerning to the current situation of biofouling in LPC, including Indonesia. This rapid national status assessment in Indonesia is carried out to determine the essential needs for developing a future national biofouling strategy and related initiatives in Indonesia. This study and assessment include the marine sectors may act as pathway for IAS into Indonesia through biofouling, the resource and socio-economic risk from biofouling, the existing policy associated with biofouling management issues, the existing gaps, capacity needs and required reforms to manage biofouling issue in Indonesia. The assessment is carried by using the guidance provided by Glofouling guide.