bluuebunny/crossref_metadata_2025_split huggingface dataset:
3D structural modeling using seismic data and well logs for Khatatba reservoir in Matruh-Shushan Basin, North Western Desert, Egypt
Authors: Eid Amr M. , Mabrouk Walid M. , Amer Mohammed , Metwally Ahmed 
Published: November 2023

AbstractMiddle Jurassic reservoirs present challenges in the northern segment of the Western Desert due to geometric uncertainties arising from structural configurations, lateral facies variations, diverse lithologies, and heterogeneous reservoir quality. Consequently, this study employed an intricate approach, constructing detailed 3D geostatic models by amalgamating diverse datasets, including 2D seismic sections and digital well-logs. The focus of these 3D models was on the Khatatba Formation (Upper-Safa Member, Kabrit Member, and Lower-Safa Member) in Matruh—Shushan Basin in the North Western Desert. The objectives encompassed assessing hydrocarbon potential, precisely estimating reserves, formulating development and exploration strategies, and identifying prospective drilling locations. The resultant structural model revealed a compartmentalized region marked by major and minor NE–SW trending normal faults, establishing structurally advantageous locations for hydrocarbon trapping within the study area. Petrophysical analyses highlighted the promising potential of the Upper-Safa Member as a reservoir, featuring porosity values ranging from 10 to 18%, peaking in the northeast sector, volume of shale (Vsh) between 15 and 24%, water saturation (Sw) spanning from 18 to 53%, and increased sand thickness towards the eastern section. Similarly, the Lower-Safa Member demonstrated favorable reservoir attributes, including porosity values ranging from 10 to 16%, with higher values in the southeastern part, Vsh between 17 and 28%, and Sw varying from 15 to 47%. The study findings underscored the hydrocarbon potential in the northeast block of the study area for the Middle Jurassic Khatatba Formation. These insights contribute valuable information for decision-making in exploration and production endeavors within the basin.
Identification and characterization of a novel heparinase PCHepII from marine bacterium Puteibacter caeruleilacunae
Authors: Lu Danrong , Wang Luping , Ning Zeting , Li Zuhui , Li Meihua , Jia Yan , Zhang Qingdong 
Published: November 2023

AbstractHeparin (HP) and heparan sulfate (HS) are multifunctional polysaccharides widely used in clinical therapy. Heparinases (Hepases) are enzymes that specifically catalyse HP and HS degradation, and they are valuable tools for studying the structure and function of these polysaccharides and for preparing low molecular weight heparins. In this study, by searching the NCBI database, a novel enzyme named PCHepII was discovered in the genome of the marine bacterium Puteibacter caeruleilacuae. Heterologously expressed PCHepII in Escherichia coli (BL21) has high expression levels and good solubility, active in sodium phosphate buffer (pH 7.0) at 20°C. PCHepII exhibits an enzyme activity of 254 mU/mg towards HP and shows weak degradation capacity for HS. More importantly, PCHepII prefers to catalyse the high-sulfated regions of HP and HS rather than the low-sulfated regions. Although PCHepII functions primarily as an endolytic Hepase, it mainly generates disaccharide products during the degradation of HP substrates over time. Investigations reveal that PCHepII exhibits a preference for catalysing the degradation of small substrates, especially HP tetrasaccharides. The catalytic sites of PCHepII include the residues His199, Tyr254, and His403, which play crucial roles in the catalytic process. The study and characterization of PCHepII can potentially benefit research and applications involving HP/HS, making it a promising enzyme.
Investigation of laser wavelength effect on the ablation of enamel and dentin using femtosecond laser pulses
Authors: Rapp Ludovic , Madden Steve , Brand Julia , Maximova Ksenia , Walsh Laurence J. , Spallek Heiko , Zuaiter Omar , Habeb Alaa , Hirst Timothy R. , Rode Andrei V. 
Published: November 2023

AbstractWe investigated the effect of femtosecond (fs) laser ablation of enamel and dentin for different pulse wavelengths: infrared (1030 nm), green (515 nm), and ultra-violet (343 nm) and for different pulse separations to determine the optimal irradiation conditions for the precise removal of dental hard tissues with the absence of structural and compositional damage. The ablation rates and efficiencies were established for all three laser wavelengths for both enamel and dentin at room temperature without using any irrigation or cooling system, and the surfaces were assessed with optical and scanning electron microscopy, optical profilometry, and Raman spectroscopy. We demonstrated that 515 nm fs irradiation provides the highest rate and efficiency for ablation, followed by infrared. Finally, we explored the temperature variations inside the dental pulp during the laser procedures for all three wavelengths and showed that the maximum increase at the optimum conditions for both infrared and green irradiations was 5.5 °C, within the acceptable limit of temperature increase during conventional dental treatments. Ultra-violet irradiation significantly increased the internal temperature of the teeth, well above the acceptable limit, and caused severe damage to tooth structures. Thus, ultra-violet is not a compatible laser wavelength for femtosecond teeth ablation.
USP18 enhances dengue virus replication by regulating mitochondrial DNA release
Authors: Lai Jenn-Haung , Wu De-Wei , Wu Chien-Hsiang , Hung Li-Feng , Huang Chuan-Yueh , Ka Shuk-Man , Chen Ann , Ho Ling-Jun 
Published: November 2023

AbstractDengue virus (DENV) infection remains a challenging health threat worldwide. Ubiquitin-specific protease 18 (USP18), which preserves the anti-interferon (IFN) effect, is an ideal target through which DENV mediates its own immune evasion. However, much of the function and mechanism of USP18 in regulating DENV replication remains incompletely understood. In addition, whether USP18 regulates DENV replication merely by causing IFN hyporesponsiveness is not clear. In the present study, by using several different approaches to block IFN signaling, including IFN neutralizing antibodies (Abs), anti-IFN receptor Abs, Janus kinase inhibitors and IFN alpha and beta receptor subunit 1 (IFNAR1)knockout cells, we showed that USP18 may regulate DENV replication in IFN-associated and IFN-unassociated manners. Localized in mitochondria, USP18 regulated the release of mitochondrial DNA (mtDNA) to the cytosol to affect viral replication, and mechanisms such as mitochondrial reactive oxygen species (mtROS) production, changes in mitochondrial membrane potential, mobilization of calcium into mitochondria, 8-oxoguanine DNA glycosylase 1 (OGG1) expression, oxidation and fragmentation of mtDNA, and opening of the mitochondrial permeability transition pore (mPTP) were involved in USP18-regulated mtDNA release to the cytosol. We therefore identify mitochondrial machineries that are regulated by USP18 to affect DENV replication and its association with IFN effects.
Dexamethasone prophylaxis protects from acute high-altitude illness by modifying the peripheral blood mononuclear cell inflammatory transcriptome
Authors: Kumar Rahul , Chanana Neha , Sharma Kavita , Palmo Tsering , Lee Michael H. , Mishra Aastha , Nolan Kevin , Fonseca Balladares Dara C. , Mickael Claudia , Gupta Mohit D. , Thinlas Tashi , Pasha Qadar , Graham Brian B. 
Published: November 2023

Abstract
Acute high-altitude (HA) exposure can induce several pathologies. Dexamethasone (DEX) can be taken prophylactically to prevent HA disease, but the mechanism by which it acts in this setting is unclear. We studied the transcriptome of peripheral blood mononuclear cells (PBMCs) from 16 subjects at low altitude (LA, 225 m) and then 3 days after acute travel to HA (3500 m) during the India-Leh-Dexamethasone-Expedition-2020 (INDEX2020). Half of the participants received oral DEX prophylaxis 4 mg twice daily in an unblinded manner, starting 1 day prior to travel to HA, and 12 h prior to the first PBMC collection. PBMC transcriptome data were obtained from 16 subjects, half of whom received DEX. The principal component analysis demonstrated a clear separation of the groups by altitude and treatment. HA exposure resulted in a large number of gene expression changes, particularly in pathways of inflammation or the regulation of cell division, translation, or transcription. DEX prophylaxis resulted in changes in fewer genes, particularly in immune pathways. The gene sets modulated by HA and DEX were distinct. Deconvolution analysis to assess PBMC subpopulations suggested changes in B-cell, T-cell, dendritic cell, and myeloid cell numbers with HA and DEX exposures. Acute HA travel and DEX prophylaxis induce significant changes in the PBMC transcriptome. The observed benefit of DEX prophylaxis against HA disease may be mediated by suppression of inflammatory pathways and changing leukocyte population distributions.
An automated procedure for the detection of the Yarkovsky effect and results from the ESA NEO Coordination Centre
Authors: Fenucci Marco , Micheli Marco , Gianotto Francesco , Faggioli Laura , Oliviero Dario , Porru Andrea , Rudawska Regina , Cano Juan Luis , Conversi Luca , Moissl Richard 
Published: November 2023

Context. The measurement of the Yarkovsky effect on near-Earth asteroids (NEAs) is common practice in orbit determination today, and the number of detections will increase with the developments of new and more accurate telescopic surveys. However, the process of finding new detections and identifying spurious ones is not yet automated, and it often relies on personal judgment.
Aims. We aim to introduce a more automated procedure that can search for NEA candidates to measure the Yarkovsky effect, and that can identify spurious detections.
Methods. The expected semi-major axis drift on an NEA caused by the Yarkovsky effect was computed with a Monte Carlo method on a statistical model of the physical parameters of the asteroid that relies on the most recent NEA population models and data. The expected drift was used to select candidates in which the Yarkovsky effect might be detected, according to the current knowledge of their orbit and the length of their observational arc. Then, a nongravitational acceleration along the transverse direction was estimated through orbit determination for each candidate. If the detected acceleration was statistically significant, we performed a statistical test to determine whether it was compatible with the Yarkovsky effect model. Finally, we determined the dependence on an isolated tracklet.
Results. Among the known NEAs, our procedure automatically found 348 detections of the Yarkovsky effect that were accepted. The results are overall compatible with the predicted trend with the inverse of the diameter, and the procedure appears to be efficient in identifying and rejecting spurious detections. This algorithm is now adopted by the ESA NEO Coordination Centre to periodically update the catalogue of NEAs with a measurable Yarkovsky effect, and the results are automatically posted on the web portal.
Mykid nach Tinea manus bullosa durch Trichophyton mentagrophytes
Authors: Schießl Jasmin , Richter Margit , Syhre Ellen , Klonowski Esther , Krüger Constanze , Uhrlaß Silke , Nenoff Pietro 
Published: November 2023

ZusammenfassungId-Reaktionen im Rahmen von Infektionen der Haut durch Erreger von Dermatomykosen sind
hierzulande wahrscheinlich weit unterdiagnostiziert. Bei einem 10-jährigen Mädchen kam es nach
dem Kontakt mit einer Katze zu einer Tinea manus bullosa. Als Erreger wurde Trichophyton mentagrophytes identifiziert und mittels Sequenzierung als
zoophiler Genotyp III* bestätigt. Behandelt wurde rein topisch mit Miconazol +
Flupredniden-Creme. In den nächsten Tagen entwickelten sich volar an beiden Handgelenken und
an den Beugeseiten der Unterarme pruriginöse Papeln und Vesiculae im Sinne eines Mykids oder
Id-Reaktion als Folge der Dermatophytose. Behandelt wurde kurzzeitig mit topischen
Glukokortikoiden, das Exanthem bildete sich schnell zurück. Die Tinea manus heilte zeitgleich
und ebenfalls folgenlos ab.
Influence of Serum Ferritin and B12 Levels in the Functional Outcomes of Patients with Ruptured and Unruptured Intracranial Aneurysms
Authors: Rabelo Nícollas Nunes , Coelho Antônio Carlos Samaia da Silva , Pipek Leonardo Zumerkorn , Telles Joao Paulo Mota , Barbato Natalia Camargo , Yoshikawa Marcia Harumy , Barbosa Guilherme Bitencourt , Teixeira Manoel Jacobsen , Figueiredo Eberval Gadelha 
Published: November 2023

Abstract
Introduction Pathological processes in the arterial wall that result in vessel dilation are the cause of intracranial aneurysms (IAs), and the risk factors for their formation and progression are not well established. Ferritin is associated with inflammation and angiogenesis; it has protective antioxidative activity, and controls cell differentiation. Vitamin B12 is related to neurological and hematological disorders; it can be used as differential diagnosis tool, and acts in the control of homocysteinemia, a predictor of worse prognosis. The present article aims to assess the correlation between serum ferritin and B12 levels and the patient's functional outcome.
Materials and Methods In the present cohort study, we assessed the serum levels of ferritin and B12, as well as the scores on the modified Rankin and Glasgow Outcome Scales at 6 months, of 2 groups, one with 19 and the other with 49 individuals, out of 401 patients treated for IA at Universidade de São Paulo from 2018 to 2019. We performed a statistical analysis, using logistic regression, to determine the aforementioned correlation.
Results In the univariable analysis, the serum levels of ferritin showed no significant impact on the functional outcome (odds ratio [OR]: 0.96 for every 100 pg/mL increase; 95% confidence interval [95%CI]: 0.761–1.210; p = 0.732); neither did the serum levels of B12 (OR: 0.998 for every 100 pg/mL increase; 95%CI: 0.826–1.206; p = 0.987). Moreover, no significant impact on the functional outcome was observed in the multivariable analysis regarding the serum levels of B12, age, hypertension, and aneurysm rupture (OR: 1.086 for every 100 pg/mL increase; 95%CI: 0.847–1.392; p = 0.513).
Conclusion We were not able to confirm a statistical correlation regarding the serum levels of ferritin and B12, and functional outcome of IA patients. These variables might be linked to other determinants of the pathophysiology of IAs, like inflammation and homocysteinemia.
Computational study on structural, elastic, mechanical and optical properties of K2AgAs ternary semiconductor compound
Authors: Musembi Robinson , Mbilo Mwende 
Published: November 2023

In this study, the structural, electronic, elastic, mechanical, and optical properties of a new Zintl phase K2AgAs ternary semiconductor compound have been investigated by the first-principles method using the plane-wave self-consistence field method. A triangulation of different exchange-correlation functionals, including local density approximation-LDA-PZ, generalized gradient approximation (GGA)-Q2D, GGA-BLYP, GGA-Perdew–Burke–Ernzerhof (PBE), GGA-PBESol, and GGA-revPBE, have been utilized to predict the properties of the material. The computed structural properties predicted that the K2AgAs compound is thermodynamically stable, and the lattice parameters are consistent with the reported experimental values. The electronic properties show that the bandgap ranges between 0.6645 and 1.1915 eV, while the conduction and valence bands are formed mainly through the hybridization of the As-2p, Ag-2p and Ag-3d, As-2p states, respectively, with other states making minimal contribution. From the calculation of elastic properties, K2AgAs were predicted to be mechanically stable. Notably, K2AgAs has been predicted to absorb light within the ultraviolet-visible regime. Owing to their good thermodynamic and mechanical stability, wide coverage of absorption in the UV-Vis region of the solar spectrum, and narrow bandgaps, K2AgAs can be formed/synthesized and applied as the active photoactive material in solar cells and other photovoltaics.
Creating an information security policyin a bank
Authors: T. Kamou Olivier Mozard 
Published: November 2023

Abstract
Information security policies are particularly important when it comes to maintaining information security within an organization. As a result, creating an information security policy is an invaluable process that cannot be undermined. This study aims at investigating how these information security policies are created, specifically in banks, from a linguistic perspective. The study employed the use of corpora and analyzed ten information security policies of banks randomly collected online. The analyses were categorized under five levels of linguistic analysis which included: the mode, lexis, grammar, speech acts, and discourse. Some statistical analyses which involved clustering were also performed at the level of discourse in order to find similar patterns in the information security policies. The results show that banks use the same linguistic features when writing their information security policies. The results also reveal how these linguistic features are used to develop a comprehensive and effective information security policy.
Effect of cooling rate on solidification points and atomic structures of metal nanoclusters: a molecular dynamics simulation study
Authors: Samantaray Minati P , Sarangi Soumya S 
Published: November 2023

Abstract
In this work, the micro-structural evolution during the solidification process of three metal nanoclusters (copper, nickel, and silver) containing 2048 atoms each, subjected to different cooling rates are investigated. Molecular dynamics (MD) simulations in conjunction with modified embedded atom method (MEAM) potentials have been employed to carry out the work. For different cooling rates, the solidification points of the nanoclusters are estimated from the variation in average potential energy of the systems during the crystallization process, and the structural evolutions are analysed by utilising radial distribution function and common neighbour analysis method. The results advocate that the cooling rate has a profound impact on the structures of the solidified nanoclusters. The critical cooling rate for each nanocluster has been captured, where a glassy/amorphous structure is observed. Polycrystalline nano-structures (consisting of amorphous, FCC and HCP) are observed below these critical cooling rates and the number of close-packed structures (FCC, HCP) are found to decrease with the increase in cooling rate. The findings of this work would be helpful in various practical applications of the metal nanoclusters, where the structure of nanoclusters directly affect.
Resonant interaction between runaway electrons and the toroidal magnetic field ripple in TCV
Authors: Wijkamp T.A. , Hoppe M. , Decker J. , Duval B.P. , Perek A. , Sheikh U. , Classen I.G.J. , Jaspers R.J.E. ,   the TCV team
Published: November 2023

Abstract
This work explains the anomalously high runaway electron (RE) pitch angles inferred in the flat-top of dedicated Tokamak à Configuration Variable (TCV) experiments. Kinetic modelling shows that the resonant interaction between the gyromotion of the electrons and the toroidal magnetic field ripple will give rise to strong pitch angle scattering in TCV. The resulting increase in synchrotron radiation power losses acts as a RE energy barrier. These observations are tested experimentally by a magnetic field ramp-down, which gradually reduces the resonant parallel momentum at which the REs interact with the ripple. Resulting changes in synchrotron emission geometry and intensity are observed using three multi-spectral camera imaging systems, viewing the RE beam at distinct spatial angles in multiple wavelength ranges. Experimental reconstructions of the RE distribution in momentum- and real-space are consistent with kinetic model predictions.
Capillary efficiency study in leaf vein morphology inspired channels
Authors: Shen Jingyu , Guo Ce , Ma Yaopeng , Dong Ao 
Published: November 2023

Abstract
Inspired by the capillary transport function of plant leaf veins, this study proposes three typical leaf vein features by observing a large number of leaves, including wedge shape, branch asymmetry, as well as hierarchical arrangement, and investigates their capillary transport mechanism. Not only a preliminary theoretical analysis of capillary flow in the bio-inspired channels was carried out, but the COMSOL Multiphysics simulation software was also used to simulate gas–liquid two-phase flow in biomimetic channels. The results reveal the efficient transport mechanism of the leaf vein inspired structure and provide insight into the design of capillary transmission channels.
On the adiabatic approximation for the laser-dressed atom
Authors: Flegel A V , Frolov M V 
Published: November 2023

Abstract
The adiabatic approximation is analyzed for non-perturbative interaction of an atomic system with an intense low-frequency laser field. We find that the well-known adiabatic ansatz, which consists in using the DC-based Green’s and wave functions for an atom in the instantaneous AC field to calculate transition matrix elements, exceeds the level of accuracy of the adiabatic approximation and requires further theoretical revision. It is shown that the non-analyticity in the field strength of the DC-based Green’s and wave functions leads to violation of the adiabaticity constrains and the appearance of rapidly oscillating components in the transition matrix elements. We suggest an improved adiabatic approach utilizing the analytical parts in the DC-based Green’s and wave functions. We illustrate our revised adiabatic approach for analysis of atomic polarizability in two-component laser field with an intense infrared and perturbative extreme ultraviolet components within the zero-range potential model.
Single flow treatment degradation of antibiotics in water using falling-film dielectric barrier discharge
Authors: XU 许 Zhiyuan 志远 , ZHANG 章 Cheng 程 , WU 伍 Yunjian 云健 , HUANG 黄 Bangdou 邦斗 , XI 席 Dengke 登科 , ZHANG 张 Xiaoxing 晓星 , SHAO 邵 Tao 涛 
Published: November 2023

Abstract
The environmental contamination caused by antibiotics is increasingly conspicuous due to their widespread manufacture and misuse. Plasma has been employed in recent years for the remediation of antibiotic pollution in the environment. In this work, a falling-film dielectric barrier discharge was used to degrade the antibiotic tetracycline (TC) in water. The reactor combined the gas-liquid discharge and active gas bubbling to improve the TC degradation performance. The discharge characteristics, chemical species’ concentration, and degradation rates at different parameters were systematically studied. Under the optimized conditions (working gas was pure oxygen, liquid flow rate was 100 mL/min, gas flow rate was 1 L/min, voltage was 20 kV, single treatment), TC was removed beyond 70% in a single flow treatment with an energy efficiency of 145 mg/(kW·h). The reactor design facilitated gas and liquid flow in the plasma area to produce more ozone in bubbles after a single flow under pure oxygen conditions, affording fast TC degradation. Furthermore, long-term stationary experiment indicated that long-lived active species can sustain the degradation of TC. Compared with other plasma treatment systems, this work offers a fast and efficient degradation method, showing significant potential in practical industrial applications.