bluuebunny/crossref_metadata_2025_split huggingface dataset:
Pathogenetic characterization of a Micrococcus luteus strain isolated from an infant
Authors: Shi Xiaolu , Qiu Shuxiang , Ji Liyin , Lu Huiqun , Wu Shuang , Chen Qiongcheng , Zou Xuan , Hu Qinghua , Feng Tiejian , Chen Shiting , Cui Wenkai , Xu Shiqin , Jiang Min , Cai Rui , Geng Yijie , Bai Qinqin , Huang Dingjie , Liu Peihui 
Published: December 2023

PurposeTo explore the clinical characteristics of Micrococcus luteus bloodstream infection in an infant and characterize the phenotype and genotype of the isolated strains, as well as seek suitable infection models for assessing virulence.MethodsClinical data was collected from an infant patient diagnosed with M. luteus bloodstream infection. Metagenomic sequencing was performed on the isolated blood sample. The strain was isolated and underwent mass spectrometry, biochemical tests, antibiotic susceptibility assays, and whole-genome sequencing. The Galleria mellonella infection model was used to assess M. luteus virulence.ResultsPatient responded poorly to cephalosporins, but recovered after Linezolid treatment. Metagenomic sequencing identified M. luteus as the predominant species in the sample, confirming infection. They were identified as M. luteus with a high confidence level of 98.99% using mass spectrometry. The strain showed positive results for Catalase, Oxidase, and Urea tests, and negative results for Mannose, Xylose, Lactose, Mannitol, Arginine, and Galactose tests, consistent with the biochemical profile of M. luteus reference standards. M. luteus susceptibility to 15 antibiotics was demonstrated and no resistance genes were detected. Predicted virulence genes, including clpB, were associated with metabolic pathways and the type VI secretion system. The infection model demonstrated dose-dependent survival rates.ConclusionThe infant likely developed a bloodstream infection with M. luteus due to compromised immunity. Although the isolated strain is sensitive to cephalosporin antibiotics and has low pathogenicity in infection models, clinical treatment with cephalosporins was ineffective. Linezolid proved to be effective, providing valuable guidance for future clinical management of such rare infections.
Preclinical evidence of reno-protective effect of quercetin on acute kidney injury: a meta-analysis of animal studies
Authors: Zeng Yi-Fan , Li Jing-Yu , Wei Xin-Yu , Ma Si-Qing , Wang Qiu-Guo , Qi Zhen , Duan Zhi-Cheng , Tan Ling , Tang Hao 
Published: December 2023

Objective: This study evaluated the reno-protective effects of quercetin in animal models of acute kidney injury (AKI).Methods: We conducted a systematic search of literature published before April 2023 in PubMed, Web of Science, and EMBASE databases. Methodological quality was assessed by SYRCLE’s RoB tool. Funnel plot, Egger’s test, and Begg’s test were used to determine publication bias.Results: A total of 19 studies with 288 animals were included in this meta-analysis. The methodology quality scores of the included studies ranged from 4 to 7. The results indicated that quercetin reduced blood urea nitrogen (SMD = −4.78; 95% CI: 6.45, −3.12; p &lt; 0.01; I2 = 84%) and serum creatinine (SMD: 2.73, 95% CI: 3.66, −1.80; p &lt; 0.01; I2 = 80%) in AKI models. The result of sensitivity analysis was stable, while the results of funnel plot indicated asymmetric. In addition, we further analyzed inflammatory cytokines, oxidative stress levels, and kidney injury scores, and found that quercetin treatment had antioxidant and anti-inflammatory effects and improved kidney injury scores in animal models of AKI.Conclusion: Quercetin exhibited a promising reno-protective effect in AKI animal models.Systematic Review Registration: PROSPERO (CRD42023433333).
SCGNet: efficient sparsely connected group convolution network for wheat grains classification
Authors: Sun Xuewei , Li Yan , Li Guohou , Jin Songlin , Zhao Wenyi , Liang Zheng , Zhang Weidong 
Published: December 2023

IntroductionEfficient and accurate varietal classification of wheat grains is crucial for maintaining varietal purity and reducing susceptibility to pests and diseases, thereby enhancing crop yield. Traditional manual and machine learning methods for wheat grain identification often suffer from inefficiencies and the use of large models. In this study, we propose a novel classification and recognition model called SCGNet, designed for rapid and efficient wheat grain classification.MethodsSpecifically, our proposed model incorporates several modules that enhance information exchange and feature multiplexing between group convolutions. This mechanism enables the network to gather feature information from each subgroup of the previous layer, facilitating effective utilization of upper-layer features. Additionally, we introduce sparsity in channel connections between groups to further reduce computational complexity without compromising accuracy. Furthermore, we design a novel classification output layer based on 3-D convolution, replacing the traditional maximum pooling layer and fully connected layer in conventional convolutional neural networks (CNNs). This modification results in more efficient classification output generation.ResultsWe conduct extensive experiments using a curated wheat grain dataset, demonstrating the superior performance of our proposed method. Our approach achieves an impressive accuracy of 99.56%, precision of 99.59%, recall of 99.55%, and an F1-score of 99.57%.DiscussionNotably, our method also exhibits the lowest number of Floating-Point Operations (FLOPs) and the number of parameters, making it a highly efficient solution for wheat grains classification.
“I don’t watch that anymore”: an analysis of online comments by German soccer fans on their relationship to their favored clubs
Authors: Kaden Martin , Brandt Christian , Bauers Sebastian Björn , Bunar Jonathan , Hovemann Gregor 
Published: December 2023

IntroductionSoccer fans are important stakeholders of their favored clubs; yet, although there is manifold literature on this subject, there are still open questions concerning supporters’ relationship and loyalty to those clubs, such as potential fan exits, where supporters turn away from their preferred team. Existing literature describes diverging evidence as to whether an exit is possible and whether fans’ loyalty prevents that response. Against this background, it is important to examine how the relationship between fans and soccer clubs presents itself from the fans’ perspective. This study focuses on German soccer fans because an increasing number of media reports note problems for the fans in this regard, reporting eroded loyalty, increasing alienation, or turning away.MethodsBy means of a qualitative and explorative approach (thematic analysis), this study analyzes online fan comments associated with the mentioned reports. A purposive sample of 17 media reports with 10,902 associated comments written/published between 2020 and 2023 was included in this study.ResultsThe thematic analysis show that fans reflect their relationship to favored clubs in three ways: negative changes in the emotional relationship, negative behavioral changes in the relationship, and no or positive changes in the relationship. A wide continuum of negative emotional and behavioral changes is identified, ranging from a deterioration of the inner bond with the favored club to different levels of ceasing soccer-related consumption. As explanations for the (potential) dynamics and changes in the relationship, fans reflect a broad and diverse field of developments in the context of German soccer. The differentiated developments are systemized within four categories: commercialization, governance, attractiveness, and the COVID-19 pandemic.DiscussionThe results are discussed and contextualized referring to the Exit-Voice-Loyalty-Framework and thematically relevant literature. Particularly far-reaching is the finding that there are indeed fans in the field of soccer who are capable of permanently abandoning (exiting) formerly supported clubs. The article concludes with theoretical and managerial implications emerging from the results, as well as limitations and areas of interest for further research.
Cognitive CAMSA: an ecological proposal to integrate cognitive performance into motor competence assessment
Authors: Montalt-García Sergio , Estevan Isaac , Romero-Martínez Jorge , Ortega-Benavent Nuria , Villarrasa-Sapiña Israel , Menescardi Cristina , García-Massó Xavier 
Published: December 2023

PurposeTo profile the participants using a system of self-organizing maps (SOM) based on their motor and cognitive performance during a dual-task version of the Canadian Agility and Movement Skill Assessment (Cognitive CAMSA).MethodsA total of 169 secondary school students (39.3% girls) volunteered to participate. The original CAMSA, cognitive CAMSA, the Corsi and Digit Span tests were used to assess (a) motor competence, (b) motor competence with cognitive load, and (c) cognitive performance, respectively. SOMs and the k-means clustering algorithm were used to establish the adolescents’ dual-task performance profiles.ResultsIncluding decision making based on verbal and visual cues in the original CAMSA significantly increased the participants’ total scores but also the time required to complete the test, while the skill score remained unchanged. However, not all the participants showed changes in their performance in the same direction during the cognitive CAMSA. Person-centered analyses by SOMs and k-means clustering identified six performance profiles with variations in the cognitive, motor skill, and time scores (H5 = 146.15, H5 = 102.68, and H5 = 108.07, respectively; all p &lt; 0.01).ConclusionThe cognitive CAMSA was shown to be a feasible field-motor test for assessing motor competence with a cognitive load in an ecological setting. Some of the profiles identified in the SOM approach represented adolescents with similar motor and cognitive performance in dual-task or single-task contexts, although other participants obtained high motor competence in single and dual-tasking while their cognitive performance declined or rose more in dual-task than in single task situations. The cognitive CAMSA emerges as a tool of great potential, applicable in educational and sports environments, to know subjects’ characteristics and try to individualize the interventions accordingly with their dual-task profile.
High doses of a national preschool program are associated with the long-term mitigation of adverse outcomes in cognitive development and life satisfaction among children who experience early stunting: a multi-site longitudinal study in Vietnam
Authors: Robinson J. A. , Dinh Phuong Thi Thu 
Published: December 2023

BackgroundStunting (low height-for-age) is a marker of cumulative developmental disadvantage that can also contribute to impaired cognitive development and poor psychological wellbeing. Several interventions designed to preserve stunted children’s developmental potential through increasing their cognitive stimulation have proven to be effective. However, their resource-intensive nature limits their sustainability and scalability in the low-and middle-income countries in which 98% of stunted children live. The current study had three aims: to identify the domains of developmental disadvantage associated with stunting at 5 years of age in the Vietnamese context; to examine the relationship between Vietnamese children’s stunting status at 5 years of age, the dose of the national preschool program they received, and their cognitive skills and psychological well-being at 4 ages; and to determine whether some doses of the national preschool program were associated with the mitigation of adverse cognitive and wellbeing outcomes among stunted children.MethodThe Young Lives Study in Vietnam (n = 2,000; 31 sites) provided archival data that allowed calculation of the approximate dose (in hours) of the preschool program received by children, and longitudinal data on children’s growth (1, 5, 8, 12, and 15 years), receptive vocabulary (5, 8, 12 and 15 years), reading skills, mathematics skills and life satisfaction (each at 8, 12, and 15 years).ResultsStunting at 5 years of age was associated with diverse aspects of financial and social disadvantage, greater exposure to health risks, lower preventive health care, and constraints on maternal care. Scores for all cognitive variables at all ages were positively associated with preschool dose and negatively associated with stunted growth at 5 years of age. That is, effects associated with stunting and preschool dose at 5 years of age continued to be found during the subsequent 10 years. High doses of preschool education (3,000 h or more) were associated with the mitigation of adverse outcomes for most cognitive variables at most ages.ConclusionThe current findings raise the possibility that generic preschool programs delivered at high dose may provide a scalable and sustainable intervention to support the life opportunities of children who experience early stunting.
A study on the prevalence of smoking habits among the student community in Aseer Region, Saudi Arabia
Authors: Kandasamy Geetha , Sam Gigi , Almanasef Mona , Almeleebia Tahani , Shorog Eman , Alshahrani Asma M. , Almohaimeed Rana A. , Hmlan Amjad , Al Suhaym Atheer Y. , Prabahar Kousalya , Veeramani Vinoth Prabhu , Amirthalingam Palanisamy , Mohammed Shorog Basmah , Mani Vasudevan 
Published: December 2023

ObjectivesA cross-sectional study was aimed to assess the prevalence of smoking habits among students at King Khalid University (KKU), Abha, KSA.MethodsThis was a cross-sectional study using a Modified Fagerstrom Tolerance Questionnaire (mFTQ), online survey was carried out among the students of KKU. This tool uses a five-point Likert scale for all seven questions, except one question on smoking during the first 2 h of the day.ResultsThe prevalence of smoking among male students was 67% (n = 243) and females 33% (n = 122). Of the current cigarette smokers, 19% had a nicotine dependence score of ≥6 (high), 48% scored 4–6 (moderate) and 33% scored &lt;4 (minimal). Association between mFTQ and the number of cigarettes per day (p &lt; 0.001), first smoke of your cigarettes (p &lt; 0.018), smoking in the morning (p &lt; 0.007), and difficulty refraining from smoking in public areas (p &lt; 0.000). The results of the current study recommend that cigarette smoking habits are a significant risk behavior among young students. The strength of this study signifies that most participants (62%) intend to quit if appropriately supported.ConclusionAccording to the findings of the current investigation, smoking was quite common among males. It raises the alarm about the critical need for adequate education to support health education initiatives, discourage teen smoking, and enhance health outcomes for the community.
The burden of cirrhosis and other chronic liver diseases due to hepatitis B in children and adolescents: results from global burden of disease study 2019
Authors: Huang Chenyang , Wu Yaxin , Zhang Chao , Ji Dong , Wang Fu-Sheng 
Published: December 2023

BackgroundThe global burden of cirrhosis and other chronic liver diseases due to hepatitis B (collectively referred to as hepatitis B-associated cirrhosis in this paper) in children and adolescents must be understood and investigated.MethodsData were extracted from the GBD database, and calculations were performed at global, regional, and national level. We calculate the incidence, prevalence, and disability-adjusted life years (DALYs) and annual average percentage changes (AAPCs).FindingsGlobally, the prevalent cases of children and adolescents with hepatitis B-associated cirrhosis decreased from 125,053.98 × 10^3 in 1990 to 46,400.33 × 10^3 in 2019. Compared with 1990, the incidence rate of cirrhosis increased in low (95.51%) and low-middle SDI areas (26.47%), whereas it decreased in other SDI areas. The AAPC of incidence has increased in low-middle SDI areas (AAPC 0.12 [95% CI: 0.04–0.20]). At the regional level, the East Asia region has experienced the largest reduction. Conversely, Western Sub-Saharan Africa was the most serious region. Notably, South Asia was the only region where the AAPC of cirrhosis incidence (AAPC 0.77 [95% CI, 0.68–0.86]) increased.ConclusionGlobally, the overall burden of hepatitis B-associated cirrhosis in children and adolescents has declined significantly, but the number of cirrhosis incidence cases in low-middle and low-SDI areas has increased. The incidence in South Asia is rising, and the burden on Africa remains serious. Prevention and treatment of hepatitis B-associated cirrhosis in children and adolescents should not be ignored.
Positional and between quarter differences in physical demands of elite female field hockey players during international matches
Authors: Powell Colin , Sparks Martinique , Pienaar Cindy 
Published: December 2023

ObjectivesThe main aims of this study were to examine whether there are positional- and between-quarter differences in the physical load of elite female field hockey players during international matches.MethodsTwenty-three international female field hockey players were equipped with Global Positioning Systems devices, while competing over nine international matches.ResultsPlayers covered a mean relative distance, relative player load, and distance covered in the form of low-, moderate-, and high intensity activities of 107.5 m/min, 10.3 AU/min, 41.6%, 47.9%, and 9.9%, respectively. Defenders achieved the lowest relative Player load (ES: 0.8–1.1) and greatest distance covered in the form of low intensity activities compared to Midfielders and Forwards (ES: 0.8–0.9). Forwards and Midfielders covered significantly greater distance in the form of high intensity activity compared to Defenders (ES: 1.6–2.2). Significant reductions in relative distance, relative Player load, and moderate intensity activity are observed for all positions between Quarters 1–4 despite the availability of unlimited substitutions. However, players were able to maintain their high intensity activity throughout the match with no significant differences between Quarters 1–4. The majority of variables were higher (ES &gt; 0.2) during Quarter 2 compared to Quarter 3, especially for Midfielders and Defenders.ConclusionsCurrent findings provide further evidence on the positional- and between-quarter external match load of international female field hockey players that coaches should consider when designing training programs and drills to better prepare players for match demands. The results also provide some insight into the fatigue experienced by players and the possible pacing strategies they employ during matches. These findings support the need for re-warm-ups and may further influence how coaches time their substitutions to enhance running performance in future.
Effect of period of receptivity and air temperature on parthenocarpic phenomenon of ‘Assiane’ date palm cultivar (Phoenix dactylifera L.)
Authors: Zahiri Imane , Alla Fouzia , Alzain Mashail N. , Alhalmi Abdulsalam , Noman Omar , Parvez Mohammed Khalid , Elhoumaizi Mohammed Aziz 
Published: December 2023

IntroductionIn hot arid regions, the productivity of certain date palm cultivars faces a significant challenge wherein non-fertilized flowers can give rise to parthenocarpic singular or triplet fruit.AimsThe aims of this study, we aimed to investigate the impact of delayed pollination on date palm yield and fruit quality, while also examining the influence of temperature on these processes.MethodsWe conducted this research using 10 15-year-old ‘Assiane’ palm trees, all situated within the Figuig Oasis environment. Pollination was performed on the same day of spathe opening, as well as up to 16 days after the initial opening. Additionally, we utilized 30 palm trees to analyze the effect of daily average temperatures.Results and DiscussionOur findings reveal that the optimal period for achieving maximum yield and fruit quality falls between the sixth and eighth day following the cracking of the female spathe. Furthermore, we observed that relatively lower temperatures, ranging from 5 to 20°C, promote the formation of parthenocarpic fruits while inhibiting the development of normal fruits. Moreover, the insights gained from investigating these issues could have broader implications for date palm cultivation in arid regions and offer valuable lessons for the preservation of oasis ecosystems worldwide.
The Incidence of Antibody-Mediated Rejection Is Age-Related, Plateaus Late After Kidney Transplantation, and Contributes Little to Graft Loss in the Older Recipients
Authors: Betjes Michiel G. H. , Kal-van Gestel Judith , Roodnat Joke I. , de Weerd Annelies E. 
Published: December 2023

It is not known whether antibody-mediated rejection (ABMR) is age-related, whether it plateaus late after transplantation, and to what extent it contributes to graft loss in older recipients. Patients transplanted between 2010 and 2015 (n = 1,054) in a single center had regular follow-up until January 2023. Recipients were divided into age groups at transplantation: 18–39 years (“young”), 40–55 years (“middle age”), and &gt;55 years (“elderly”). Ten years after transplantation the cumulative % of recipients with ABMR was 17% in young, 15% in middle age, and 12% in elderly recipients (p &lt; 0.001). The cumulative incidence of ABMR increased over time and plateaued 8–10 years after transplantation. In the elderly, with a median follow-up of 7.5 years, on average 30% of the recipients with ABMR died with a functional graft and ABMR contributed only 4% to overall graft loss in this group. These results were cross-validated in a cohort of recipients with &gt;15 years follow-up. Multivariate cox-regression analysis showed that increasing recipient age was independently associated with decreasing risk for ABMR. In conclusion, the cumulative risk for ABMR is age-dependent, plateaus late after transplantation, and contributes little to overall graft loss in older recipients.
NURSE ROTATION TO THE INCIDENCE OF BURNOUT SYNDROME
Authors: Pujiyanto Tri Ismu , Hapsari Shindi , Nur Rohman Nopi Bagus 
Published: December 2023

The prevalence of burnout among nursing professionals is very high, which is associated with gender, age, marital status, level of health, occupational shifts and health care areas. Job rotation is one way out of the problems that are occurring. This study was to determine the relationship between nurse rotation and burnout syndrome. This study uses a quantitative research design with a cros-sectional approach to explain the variable of job rotation with the incidence of burnout syndrome in nurses. A population of 130 nurses with sampling techniques using the slovin formula was obtained by 98 respondents with the criteria of ASN nurses who work in mental wards, nurses who have experienced job rotation. The Instrument used nurse rotation questionnaire and Maslach Burnout Inventory-Human Services Survey questionnaire. Data analysis using pearson correlation tests. Research shows a relationship between job rotation and the incidence of nurse burnout syndrome with an r value of 0.900 then a p value of 0.000. The nurse's good perception of job rotation is the lower the incidence of burnout in nurses and to provide a good plan related to the nurse job rotation program and adjust the workload so as to improve the performance of good nurses.Keywords: Burnout Syndrome; Job Rotation; Nurse