bluuebunny/crossref_metadata_2025_split huggingface dataset:
The characteristic of myxosporean infection in several organs of nile tilapia cultivation
Authors: Yunus M , Sunarso A , Wijaya A 
Published: January 2024

AbstractThe myxosporean is a parasite that frequently infects several fish organs, therefore it can be identified by histopathologically assessing the character of the infection in the infected organs. The present study was carried out to assess the infection of myxosporean (Myxobolussp.) in nile tilapia cultivation by observing the histomorphological characteristic of several organs. Live Nile tilapia sample from Gresik cultivations immediately was done necropsy and observation on gill, intestine and liver. Histological preparation was made for the gills, liver and intestines and observed with HE staining. In the gills of nile tilapia, variable numbers of active spore ofMyxobolussp. can displace the gill lamellae, inflammatory and incite hyperplastic responses, lamellar fusion, and gill distortion in several infections. The spore infiltrates the surface of the liver of the host causing serious damage to the liver tissue. Fish infected with the parasite exhibit necrosis and cysts in the gut. Parasites were detected within multiple segments of the intestine. While occurrences within the intestinal lumen were infrequent, conspicuous clinical indications were notably absent upon inspection of the fish’s external body surface. The findings unequivocally establish thatMyxobolussp. infection in tilapia induces substantial damage to the crucial organs of the fish.
Surface quality evaluation through 3D profilometry of dental restoration performed in a clinical simulated environment
Authors: Calmon Kezia dos Santos , Perez Cesar dos Reis , Maru Marcia Marie 
Published: January 2024

Abstract
This study evaluated the surface quality of Class V composite resin restorations, comparing the surface roughness resulting from applying three techniques for finishing and polishing in a condition of clinical simulated environment by using artificial dental arcade. Beyond the aesthetic aspect, the importance of the surface quality of the restoration is associated with biofilm accumulation that occur on the teeth restored surface depending on the roughness level, leading to carious lesions and gingivitis. The minimum roughness considered ideal to avoid the accumulation of bacterial biofilm, is 0.2 μm, and 0.5 μm for tactile perception. Most of the evaluations of the surface quality of restorative materials are performed in flat specimens, and the results can significantly differ from the clinical scenario. The present work discloses how heterogeneous the surface quality may result when dealing with natural teeth. The finishing and polishing techniques selected in this work comprised diamond burs and rubber points, diamond burs and surface sealant, and abrasive discs, for restoring premolar natural teeth using a commercial composite resin. The surface quality of the restoration resulting from the three techniques was investigated through Ra, Rt, Rp, R, Rk, Rpk, Rvk and RSm roughness parameters, extracted from 3D topography maps. It was found that the use of abrasive discs (G3) promoted better surface quality, with mean Ra roughness near 0.4 μm, against 0.6 μm for the surface sealant group (G2) and 1.0 μm for the rubber points group (G1). It was evidenced that, together with Ra, analyses of roughness parameters regarding the proportion of peaks and valleys, in this case, Rp and Rpk, and roughness spacing, RSm, were significant to gain confidence and reveal reliable screening of the performance between the three techniques, with the best surface condition of the restored area resulting from the use of abrasive discs.
Dual heteroatom-doped biomass-derived porous carbon anode for superior sodium storage
Authors: Li Yinyin , Zhu Jianhui , Song Liang , Wang Yanyi , Ma Dingtao , Sun Shichang , Zhang Peixin 
Published: January 2024

Abstract
The green preparation of anode materials is desirable for high-performance sodium-ion batteries. In this paper, a N/S co-doped porous carbon was prepared from longan shell via a facile and low-cost route. Heteroatom doping increases the defect sites to facilitate Na+ storage and improves the electronic conductivity of the carbon material. The N/S co-doped porous carbon prepared using CS(NH2)2 with a ratio of 1:2 displays the highest specific capacity of 314.7 mAh g−1 after 200 cycles at 0.1 A g−1. In addition, a reversible specific capacity of 202.5 mAh g−1 is maintained after 1000 cycles at 1 A g−1. This work offers a new strategy for designing high-performance anode materials for sodium energy storage applications.
Synthesized uniform-different sizes silver nanoparticles using TSC and SBH simultaneously for antibacterial application
Authors: Hue Do Thi , Hiep Hoang Phu 
Published: January 2024

Abstract
Silver nanoparticles (AgNPs) in the form of nanospheres from a few nm to 100 nm in diameter were synthesized in a controlled manner using a combination of two reducing agents: sodium borohydride (SBH) and trisodium citrate (TSC). The influence of the size of AgNPs on antibacterial activity was investigated with different concentrations of AgNPs on two types of bacteria: Pseudomonas aeruginosa (PA) and Staphylococcus aureus resistant (SA) while the positive control was Ampicillin (Amp) 50 μg/ml and the negative control was water. AgNPs were investigated for morphology, size and size distribution using transmission electron microscopy (TEM) and dynamic light scattering (DLS) measurements. The optical properties of the AgNPs were investigated by recording their UV–vis absorption spectra. The antimicrobial activity of AgNPs was determined using the disc diffusion method. The results showed that the antibacterial ability of AgNPs depends on both concentration and particle size. With a particle concentration of 50 μg ml−1, the antibacterial ability is the best. The smaller the particle size, the higher the antibacterial ability. The simultaneous use of two reducing agents TSC and SBH is the novelty of the article to synthesize AgNPs particles that are uniform in shape and size while controlling the particle size. On that basis, their antibacterial performance is increased.
Enhancing machining performance of EN24 steel with CVD diamond coated tool and minimal quantity lubrication
Authors: Parray Mohammad Arif , Din Sajad Hussain , Wani M F 
Published: January 2024

Abstract
The research aims to investigate the effect of chemical vapour deposition (CVD) diamond coatings on cemented tungsten carbide (WC-Co) inserts when machining EN24 steel. In addition to the diamond coating, the research also incorporates the use of minimal quantity lubrication (MQL) technique during the machining process. The research involves experimental studies to evaluate the machinability characteristics of EN24 steel using tungsten carbide cutting inserts with diamond coatings and MQL. Diamond-coated tools are extremely effective in machining EN24 steel, particularly in applications requiring high precision, wear resistance, and long tool life. They are commonly used in industries such as aerospace, automotive, and manufacturing, where quality and durability of the machined components are critical. L12 orthogonal array was used to design experiments with the type of cutting insert used, test condition and cutting speed as control factors. Various parameters such as tool wear, cutting temperature and surface roughness were measured and compared with conventional machining techniques. The results reveal that average flank wear of cutting inserts decreased by 67.4% as a result of MQL when compared with dry machining conditions. Average flank wear decreased by 77.6% after diamond coating were applied compared with uncoated inserts. Diamond coated inserts subjected to MQL exhibit largest percentage reduction of 74.11% for surface roughness when compared to uncoated inserts. The average cutting temperature decreased by 53.09% due to MQL compared to dry machining.
Experimental investigation of physical, mechanical, and thermal behaviour of Bi-directional date palm fiber reinforced epoxy composite
Authors: Pradhan Madhusmita , Banerjee M K , Patnaik Amar 
Published: January 2024

Abstract
The present study attempts to fabricate lightweight polymer composites with superior physical, mechanical, and insulating properties by vacuum-assisted resin transfer molding (VARTM) technique. This produces bidirectional woven palm fiber epoxy composites with four different fiber loading i.e. 27, 28, 29, and 30 Wt%. The epoxy composite processed with VARTM technique has been characterized by physical, mechanical, and thermal properties along with increasing fiber loading. The test results signified that the mechanical properties including tensile, interlaminar shear, hardness, and impact strength improve with fiber loading. The maximum tensile strength and tensile modulus were observed at a fiber loading of 30 wt%, resulting in values of 64.852 MPa and 3.74 GPa, respectively. The recorded ILSS values for the epoxy composites loaded with 30 wt% were found to be 7.28 MPa. The observed improvements in the mechanical characteristics of the composite produced by the VARTM technology can be attributed to the enhanced interfacial bonding between the matrix and discontinuous prepreg fiber (DPF). The identification of a superior composite, known as DPF-4, was achieved through the incorporation of 30 wt% of bi-directional palm fiber loading. This resulted in notable improvements in the mechanical properties of the composite, as a significant enhancement of 311% and 173% in tensile and impact strength, respectively. These mechanically strengthened epoxy composites could be used as low-grade housing, structural, and automobile component applications.
Sex-based differences in the phenotypic expression and prognosis of idiopathic non-ischaemic cardiomyopathy: a cardiovascular magnetic resonance study
Authors: Mallabone Maggie , Labib Dina , Abdelhaleem Ahmed , Dykstra Steven , Thompson Richard B , Paterson D Ian , Thompson Sam K , Hasanzadeh Fereshteh , Mikami Yoko , Rivest Sandra , Flewitt Jacqueline , Feng Yuanchao , Macdonald Matthew , King Melanie , Bristow Michael , Kolman Louis , Howarth Andrew G , Lydell Carmen P , Miller Robert J H , Fine Nowell M , White James A 
Published: January 2024

Abstract

Aims
We sought to characterize sex-related differences in cardiovascular magnetic resonance-based cardiovascular phenotypes and prognosis in patients with idiopathic non-ischaemic cardiomyopathy (NICM).

Methods and results
Patients with NICM enrolled in the Cardiovascular Imaging Registry of Calgary (CIROC) between 2015 and 2021 were identified. Z-score values for chamber volumes and function were calculated as standard deviation from mean values of 157 sex-matched healthy volunteers, ensuring reported differences were independent of known sex-dependencies. Patients were followed for the composite outcome of all-cause mortality, heart failure admission, or ventricular arrhythmia. A total of 747 patients were studied, 531 (71%) males. By Z-score values, females showed significantly higher left ventricular (LV) ejection fraction (EF; median difference 1 SD) and right ventricular (RV) EF (difference 0.6 SD) with greater LV mass (difference 2.1 SD; P &lt; 0.01 for all) vs. males despite similar chamber volumes. Females had a significantly lower prevalence of mid-wall striae (MWS) fibrosis (22% vs. 34%; P &lt; 0.001). Over a median follow-up of 4.7 years, 173 patients (23%) developed the composite outcome, with equal distribution in males and females. LV EF and MWS were significant independent predictors of the outcome (respective HR [95% CI] 0.97 [0.95–0.99] and 1.6 [1.2–2.3]; P = 0.003 and 0.005). There was no association of sex with the outcome.

Conclusion
In a large contemporary cohort, NICM was uniquely expressed in females vs. males. Despite similar chamber dilation, females demonstrated greater concentric remodelling, lower reductions in bi-ventricular function, and a lower burden of replacement fibrosis. Overall, their prognosis remained similar to male patients with NICM.
Transcatheter aortic valve implantation in severe aortic stenosis does not necessarily reverse left ventricular myocardial damage: data of long-term follow-up
Authors: Myon Frederic , Marut Benjamin , Kosmala Wojciech , Auffret Vincent , Leurent Guillaume , L’official Guillaume , Curtis Elizabeth , Le Breton Herve , Oger Emmanuel , Donal Erwan 
Published: January 2024

Abstract

Aims
Aortic stenosis (AS) is causing myocardial damage and replacement is mainly indicated based on symptoms. Non-invasive estimation of myocardial work (MW) provides a less afterload-dependent too for assessing myocardial function. We sought to look at the impact of transcatheter aortic valve implantation (TAVI) on the myocardium at long-term follow-up and according to current indications.

Methods and results
We conducted an observational, cross-sectional, single-centre study. Patients were selected based on the validated indication for a TAVI. Standardized echocardiographies were repeated. A total of 102 patients were included. The mean age was 85 years, 45% were female, 68% had high blood pressure, and 52% had a coronary disease. One-fifth was suffering from low-flow–low-gradient AS. A follow-up was performed at 22 ± 9.5 months after the TAVI. No TAVI dysfunction was observed. Left ventricular (LV) ejection fraction was stable (62 ± 8%), and global longitudinal strain had improved (−14.0 ± 3.7 vs. −16.0 ± 3.6%, P &lt; 0.0001). No improvement of the MW parameters was noticed (LV global work index 2099 ± 692 vs. 2066 ± 706 mmHg%, P = 0.8, LV global constructive 2463 ± 736 vs. 2463 ± 676 mmHg%, P = 0.8). Global wasted work increased [214 (149; 357) vs. 247 (177; 394) mmHg%, P = 0.0008].

Conclusion
In a population of severe symptomatic AS patients who had undergone a TAVI, the non-invasive myocardial indices that assess the LV performance at long-term follow-up did not improve. These results are questioning the timing of the intervention and the need for more attention in the pharmacological management of these AS patients.
Pre-hospital rule-out of non-ST-segment elevation acute coronary syndrome by a single troponin: final one-year outcomes of the ARTICA randomised trial
Authors: Aarts Goaris W A , Camaro Cyril , Adang Eddy M M , Rodwell Laura , van Hout Roger , Brok Gijs , Hoare Anouk , de Pooter Frank , de Wit Walter , Cramer Gilbert E , van Kimmenade Roland R J , Ouwendijk Eva , Rutten Martijn H , Zegers Erwin , van Geuns Robert-Jan M , Gomes Marc E R , Damman Peter , van Royen Niels 
Published: January 2024

Abstract

Background and aims
The healthcare burden of acute chest pain is enormous. In the randomized ARTICA trial, we showed that pre-hospital identification of low-risk patients and rule-out of non-ST-segment elevation acute coronary syndrome (NSTE-ACS) with point-of-care (POC) troponin measurement reduces 30-day healthcare costs with low major adverse cardiac events (MACE) incidence. Here we present the final 1-year results of the ARTICA trial.

Methods
Low-risk patients with suspected NSTE-ACS were randomized to pre-hospital rule-out with POC troponin measurement or emergency department (ED) transfer. Primary 1-year outcome was healthcare costs. Secondary outcomes were safety, quality of life (QoL), and cost-effectiveness. Safety was defined as a 1-year MACE consisting of ACS, unplanned revascularization, or all-cause death. QoL was measured with EuroQol-5D-5L questionnaires. Cost-effectiveness was defined as 1-year healthcare costs difference per QoL difference.

Results
Follow-up was completed for all 863 patients. Healthcare costs were significantly lower in the pre-hospital strategy (€1932 ± €2784 vs. €2649 ± €2750), mean difference €717 [95% confidence interval (CI) €347 to €1087; P &lt; 0.001]. In the total population, the 1-year MACE rate was comparable between groups [5.1% (22/434) in the pre-hospital strategy vs. 4.2% (18/429) in the ED strategy; P = 0.54]. In the ruled-out ACS population, 1-year MACE remained low [1.7% (7/419) vs. 1.4% (6/417)], risk difference 0.2% (95% CI −1.4% to 1.9%; P = 0.79). QoL showed no significant difference between strategies.

Conclusions
Pre-hospital rule-out of NSTE-ACS with POC troponin testing in low-risk patients is cost-effective, as expressed by a sustainable healthcare cost reduction and no significant effect on QoL. One-year MACE remained low for both strategies.
Genomic Architecture Predicts Tree Topology, Population Structuring, and Demographic History in Amazonian Birds
Authors: Thom Gregory , Moreira Lucas Rocha , Batista Romina , Gehara Marcelo , Aleixo Alexandre , Smith Brian Tilston 
Published: January 2024

Abstract
Geographic barriers are frequently invoked to explain genetic structuring across the landscape. However, inferences on the spatial and temporal origins of population variation have been largely limited to evolutionary neutral models, ignoring the potential role of natural selection and intrinsic genomic processes known as genomic architecture in producing heterogeneity in differentiation across the genome. To test how variation in genomic characteristics (e.g. recombination rate) impacts our ability to reconstruct general patterns of differentiation between species that cooccur across geographic barriers, we sequenced the whole genomes of multiple bird populations that are distributed across rivers in southeastern Amazonia. We found that phylogenetic relationships within species and demographic parameters varied across the genome in predictable ways. Genetic diversity was positively associated with recombination rate and negatively associated with species tree support. Gene flow was less pervasive in genomic regions of low recombination, making these windows more likely to retain patterns of population structuring that matched the species tree. We further found that approximately a third of the genome showed evidence of selective sweeps and linked selection, skewing genome-wide estimates of effective population sizes and gene flow between populations toward lower values. In sum, we showed that the effects of intrinsic genomic characteristics and selection can be disentangled from neutral processes to elucidate spatial patterns of population differentiation.
Leguminous green manure intercropping changes the soil microbial community and increases soil nutrients and key quality components of tea leaves
Authors: Duan Yu , Wang Ting , Lei Xiaogang , Cao Yu , Liu Lefeng , Zou Zhongwei , Ma Yuanchun , Zhu Xujun , Fang Wanping 
Published: January 2024

Abstract
Intercropping, a green and sustainable planting pattern, has demonstrated positive effects on plant growth and the soil environment. However, there is currently little research on the influence of intercropping leguminous plants and using them as green manure on the soil environment and tea quality. During the profuse flowering period of Chinese milkvetch, the contents of tea amino acids and soluble sugar in intercropping tea plants with soybean increased by 6.89 and 54.58%. Moreover, there was 27.42% increase in soil ammonium nitrogen and 21.63% increase in available nitrogen. When Chinese milkvetch was returned to soil for 1 month during its profuse flowering period, the soybean and Chinese milkvetch as green manure enhanced tea amino acids and soluble sugar by 9.11 and 33.96%, and soil ammonium nitrogen, nitrate nitrogen and available nitrogen increased by 25.04, 77.84, and 48.90%. Intercropping systems also have positive effects on tea quality components, soil fertility, and soil microbial communities during the profuse flowering period of soybeans and when soybeans with this period were returned to the field for 1 month. Furthermore, the soil fertility index was significantly increased, especially in the intercropping system of tea–soybean–Chinese milkvetch. The soil bacterial community complexity and fungal community interactions were significantly increased. Soil pH, nitrate nitrogen, and available phosphorus were found to be crucial influencing factors on soil microbial communities, specifically bacterial communities. These results highlight the significance of optimizing intercropping systems to improve the soil environment and tea quality components. They also provide a theoretical foundation for promoting the sustainable development of tea plantations.
Management of pharmaceutical services in the fight against COVID-19 in universal public health systems: a rapid review
Authors: Augusti Júlia Vasconcellos , Silva Sarah Nascimento 
Published: January 2024

Abstract

Introduction
The coronavirus disease 2019 (COVID-19) pandemic brought new challenges and lessons were learnt for health services. In the field of pharmaceutical care, several interventions have been proposed to optimize and expand the response capacity of services.

Objective
To identify and characterize interventions performed in the management of pharmaceutical services during the COVID-19 pandemic in universal public health systems.

Methods
A rapid literature review was conducted and registered in PROSPERO (CRD42022360902). Systematic searches in the MEDLINE (PubMed), Embase, and Virtual Health Library databases were conducted to identify interventions and practices adopted for the management of pharmaceutical care during the COVID-19 pandemic.

Results
Thirteen articles reporting interventions developed in six countries were included. The interventions were summarized under three major themes: actions for continuous access to medicines, logistical measures for acquisition and storage, and organizational strategies. Telepharmacy services stand out as a typical action adopted in different services, which highlights the use and consolidation of digital technologies in these services. Strategies for process management were described and focused on the reorganization of the internal service of pharmacies, flow of services, and people management.

Conclusions
Many interventions were developed during the pandemic, some of which have already been incorporated into routine service delivery. Although the studies did not measure the effect of each intervention, the strategies developed are a source of information for the future delivery of care. Studies should be conducted to evaluate the potential of similar interventions in other health emergency contexts.
Weight 11 Compactly Supported Cohomology of Moduli Spaces of Curves
Authors: Payne Sam , Willwacher Thomas 
Published: January 2024

Abstract
We study the weight 11 part of the compactly supported cohomology of the moduli space of curves ${\mathcal{M}}_{g,n}$, using graph complex techniques, with particular attention to the case $n = 0$. As applications, we prove new nonvanishing results for the cohomology of ${\mathcal{M}}_{g}$, and exponential growth with $g$, in a wide range of degrees.