bluuebunny/crossref_metadata_2025_split huggingface dataset:
Theoretically Designed Cu10Sn3‐Cu‐SnOx as Three‐Component Electrocatalyst for Efficient and Tunable CO2 Reduction to Syngas
Authors: Woldu Abebe R. , Harrath Karim , Huang Zanling , Wang Xiaoming , Huang Xiao‐Chun , Astruc Didier , Hu Liangsheng 
Published: December 2023

AbstractElectrocatalytic transformation of CO2 to various syngas compositions is an exceedingly attractive approach to carbon‐neutral recycling. Meanwhile, the achievement of selectivity, stability, and tunability of product ratios using single‐component electrocatalysts is challenging. Herein, the theoretically‐assisted design of the triple‐component nanocomposite electrocatalyst Cu10Sn3‐Cu‐SnOx that addresses this challenge is presented. It is shown that Cu10Sn3 is a valuable electrocatalyst for suitable CO2 reduction to CO, SnO2 for CO2 reduction to formate at large overpotentials, and that the Cu–SnO2 interface facilitates H2 evolution. Accordingly, the interaction between the three functional components affords tunable CO/H2 ratios, from 1:2 to 2:1, of the produced syngas by controlling the applied potentials and relative contents of functional components. The syngas generation is selective (Faradaic efficiency, FE = 100%) at relatively lower cathodic potentials, whereas formate is the only liquid product detected at relatively higher cathodic potentials. The theoretically guided design approach therefore provides a new opportunity to boost the selectivity and stability of CO2 reduction to tunable syngas.
Automated Purification of DNA Origami with SPRI Beads
Authors: Chau Chalmers , Mohanan Gayathri , Macaulay Iain , Actis Paolo , Wälti Christoph 
Published: December 2023

AbstractDNA origami synthesis is a well‐established technique with wide‐ranging applications. In most cases, the synthesized origami must be purified to remove excess materials such as DNA oligos and other functional molecules. While several purification techniques are routinely used, all have limitations, and cannot be integrated with robotic systems. Here the use of solid‐phase reversible immobilization (SPRI) beads as a scalable, high‐throughput, and automatable method to purify DNA origami is demonstrated. Not only can this method remove unreacted oligos and biomolecules with yields comparable to existing methods while maintaining the high structural integrity of the origami, but it can also be integrated into an automated workflow to purify simultaneously large numbers and quantities of samples. It is envisioned that the SPRI beads purification method will improve the scalability of DNA nanostructures synthesis both for research and commercial applications.
Pull‐off capacity of FRP–concrete composite bonded with epoxy/geopolymer at elevated temperature
Authors: Rashid Khuram , Fatima Miral , Daud Maheen , Ju Minkwan , Wang Yi 
Published: December 2023

AbstractExternally bonded strengthening technique to the concrete has been widely used with epoxy adhesive. However, the adhesive is considerably weak against high temperatures, which has been regarded as the critical point in the loss of integrity of the strengthened system. Alternatively, geopolymer materials have shown an excellent performance at high temperatures, thus, their potential to be used as adhesive material has been investigated in this work. In experimentation, the composite specimens were developed using both types of adhesives, epoxy and geopolymer, and their performance was evaluated at three temperature levels (20, 60, and 120°C) by conducting pull‐off strength tests and classifying their failure modes. It was observed that the strength of concrete and epoxy was reduced with temperature. In contrast, the strength of geopolymer‐based adhesives strength was increased due to the reactivity of the precursor at high temperatures. Also, bond strength was reduced for both composite specimens at elevated temperatures. The highest bond strength was observed for the epoxy‐based adhesive system at 20°C, and about 70% loss in bond strength was observed when exposed to 120°C. The failure mode was also shifted from concrete to adhesive interface failure, that is, failure between the adhesive and the fiber fabric layer. The geopolymer‐based adhesive system has lower strength than its counterpart at all temperature levels, and the failure mode was adhesive interface failure. To enhance the bonding capacity at high temperatures, efforts are being made by adding different minerals has been employed. From the experimental results, it was found that there were some improvements, however, it was still less than that of epoxy‐based system. Further optimization of the geopolymer adhesive using minerals is required and then high‐thermal resistance geopolymer adhesive can be established.
Strain rate sensitivity of strain‐hardening fiber‐reinforced concrete subjected to dynamic direct tensile loading
Authors: Vu Vu Truong , Tran Tuan Kiet , Kim Dong Joo , Nguyen Duy‐Liem , Tran Ngoc Thanh 
Published: December 2023

AbstractThis study investigates the effects of matrix strength on the high‐rate tensile resistance and strain rate sensitivity of strain‐hardening fiber‐reinforced concretes (SHFRCs) under direct tensile loading. Two types of deformed steel fiber, hooked and twisted, were reinforced in two matrices, high‐performance concrete (HPC) with compressive strength of 84 MPa and ultra‐high‐performance concrete (UHPC) with compressive strength of 180 MPa. Additionally, an artificial neural network (ANN) based model was proposed to estimate the strain rate sensitivity of SHFRCs subjected to dynamic direct tensile loading. The results showed that HPC produced relatively lower post cracking strength but much higher strain capacity at a high strain rate than UHPC. Moreover, HPC was found to be more strain rate sensitivity than UHPC. Furthermore, the proposed ANN model was an efficient tool for predicting the strain rate sensitivity of SHFRCs. Based on the sensitivity analysis, the contribution of each influence factor on the final strain rate sensitivity of SHFRCs can be determined.
A functional chicken‐liver hydrolysate‐based supplement ameliorates alcohol liver disease via regulation of antioxidation, anti‐inflammation, and antiapoptosis
Authors: Wu Yi‐Hsieng Samuel , Lin Yi‐Ling , Kao Yi‐Feng , Chen Jr‐Wei , Chen Yi‐Chou , Chen Yi‐Chen 
Published: December 2023

AbstractTons of broiler livers are produced yearly in Taiwan but always considered waste. Our team has successfully patented and characterized a chicken‐liver hydrolysate (CLH) with several biofunctions. Chronic alcohol consumption causes hepatosteatosis or even hepatitis, cirrhosis, and cancers. This study was to investigate the hepatoprotection of CLH‐based supplement (GBHP01™) against chronic alcohol consumption. Results showed that GBHP01™ could reduce (p < .05) enlarged liver size, lipid accumulation/steatosis scores, and higher serum AST, ALT, γ‐GT, triglyceride, and cholesterol levels induced by an alcoholic liquid diet. GBHP01™ reduced liver inflammation and apoptosis in alcoholic liquid‐diet‐fed mice via decreasing TBARS, interleukin‐6, interleukin‐1β, and tumor necrosis factor‐α levels, increasing reduced GSH/TEAC levels and activities of SOD, CAT and GPx, as well as downregulating CYP2E1, BAX/BCL2, Cleaved CASPASE‐9/Total CASPASE‐9 and Active CASPASE‐3/Pro‐CASPASE‐3 (p < .05). Furthermore, GBHP01™ elevated hepatic alcohol metabolism (ADH and ALDH activities) (p < .05). In conclusion, this study prove the hepatoprotection of GBHP01™ against alcohol consumption.
The Five Emerging Business Models of Fintech for AI Adoption, Growth and Building Trust
Authors: Zarifis Alex , Cheng Xusen 
Published: December 2023

AbstractFinancial technology, Fintech, is going through a very disruptive digital transformation that is going beyond just making existing models leaner and faster. This research uses a qualitative approach to identify five models of Fintech that can utilize AI to its full potential. The five models are: (a) an incumbent in finance disaggregating and focusing on one part of the supply chain, (b) an incumbent utilizing AI in their current processes without changing their business model, (c) an incumbent extending their model to utilize AI and access new customers and data, (d) a new disrupting startup only getting involved in finance utilizing AI to gain an advantage over incumbents, and (e) an existing tech company disrupting finance by adding financial services to their portfolio of services. The five Fintech business models give an organization five proven routes to AI adoption and growth. Building trust is central to all five models. Trust is not always built at the same point in the value chain, or by the same type of organization. The trust building should usually happen where the customers are attracted and on-boarded.
Circular Construction Principles: From Theoretical Perspective to Practical Application in Public Procurement
Authors: Andabaka Ana 
Published: December 2023

AbstractThis paper aims to highlight the role of government and other public authorities in promoting the implementation of circular economy principles in the built environment. Circular construction ecosystem is based on circular building design and the coordinated action of stakeholders along the value chain. Government and local authorities have a special role to play in the built environment as they manage infrastructure and act as regulators and enablers as well. Moreover, circular building design strategies should be encouraged through the government policy tools like public procurement allowing public authorities to formulate tenders that incorporate circular economy principles when purchasing goods, services, and works related to the built environment. The case studies presented show that public procurement can be a valuable tool for promoting circular use of materials and reducing waste, encouraging the construction of circularly designed zero-emission buildings, and stimulating market innovation that reduces the environmental impact of construction while providing benefits to society. Thus, public authorities can be a powerful force driving change and innovation in the construction industry towards more circularity in the built environment.
Albanian Green Economy Trends
Authors: Prendi Llambi , Gashi Jonida 
Published: December 2023

AbstractIn the 1991s, Albania entered a great political and economic transition, passing from the communist to the capitalist system. All resources in common use were usurped. The environment and its conservation were the least concern for Albania. Even now its environment faces several problems. Some of the key issues are pollution, waste disposal, loss of biodiversity, deforestation, etc. Our paper uses data generated by OECD stat and abundant literature. We have selected OECD Green Growth indicators for monitoring progress towards green growth in Albania as environmental and resource productivity, the environmental dimension of quality of life, economic opportunities and policy responses, and the socio-economic context. The data values collected vary from 1980 to 2021. We rely on Albania's performance over time of many green growth indicators. This will allow us to observe whether Albania is moving toward a green economy and policies. From the data presented we see that Albania has made some advancements toward green growth.
PV and Thermal Solar Systems Application in Buildings. A State of Art in the Context of Circular Economy
Authors: De Simone Marilena 
Published: December 2023

AbstractSolar energy is one of the most promising sources for low carbon energy production. In particular, PV panels and thermal solar collectors can be easily integrated into new and existing buildings to improve their energy efficiency and sustainability. On the other hand, solar-based technologies require extraction of natural resources and processing, thus materials conservation and recovery are vital to effectively contribute to the decarbonization of the construction sector. The paper is meant to be a brief state of the art that summarizes the relevant issues for achieving the goal of circular economy of buildings with the focus on solar energy application, with the novelty of considering and comparing two technologies, photovoltaic and thermal. Most of the scientific literature was dedicated to PV technologies due to the increasing importance of the electrification process and the usage of materials with reduced availability. Thermal solar collectors were mainly analysed developing LCA without a larger point of view embracing circularity concepts. Apart from the technological matters, the investigation highlights social, behavioral, and economic aspects that can be crucial to trace the route to circular economy.
Wood-Based Waste Management—Important Resources for Construction of the Built Environment
Authors: Parobek Jan , Paluš Hubert 
Published: December 2023

AbstractThe circular economy focuses on the utilisation of resources and the reutilisation of these resources and waste streams into value added products. Wood as a renewable resources represent one of the most important advantage of the forest based industry and all related industries. These sectors aim on the sustainable wood and different wood products production and utilisation, wood buildings including. Improved utilization of available industrial wood assortments and utilisation of wood waste to added value products generate profit for all actors in the supply chain. Analysis of wood flows take into account not only the uses of wood as a material, but also by-products and waste generated by the production to be used as inputs for further uses in construction, wood processing or energy sectors. This paper deals with the analysis of raw wood flows in Slovakia with a focus on wood-based waste management, utilisation of wood waste for long term wood products in the built environment. At the present time new approaches such as cascade use of woody biomass can be applied to ensure the sustainable utilisation of renewable resources. The material flow analysis (MFA)was used to identify relations between the resources and primary uses of wood. In particular the results show some particular examples of wood flows focused on possibilities of utilisation of wood waste from the wood processing industry (WPI) and recycled wood in the construction sector.
How Does ‘Locality’ Matter in Enabling a Circular Built Environment?: A Focus on Space, Knowledge, and Cities
Authors: Çidik Mustafa Selçuk , Schiller Georg , Zhang Ning , Rizzo Agatino , Tambovceva Tatjana , Bajare Diana , Hendawy Mennatullah 
Published: December 2023

AbstractThere is a growing interest in understanding and using local knowledge, resources, and stakeholders to achieve tailored and effective circular solutions in the built environment. Although the importance of clear centralised guidance and regulations are emphasised in the existing literature, there is also an emerging acknowledgement that understanding the ‘local context’ will be key to achieving tailored solutions that can effectively work in practice. However, there is a lack of discussion around the meaning and significance of ‘locality’ in terms of circularity solutions in the built environment. This discussion paper introduces space (both physical and social) and knowledge as two key aspects of ‘locality’ for enabling effective circular solutions in the built environment. Further, it argues that the cities can be seen as the locus of circular economy because of their role in localising space and knowledge. Thus, the paper enables a starting point to structure research towards an improved understanding of (i) the role of space and knowledge co-production for a circular built environment, (ii) the relevant local stakeholders, as well as (iii) city-level governance of locality in supporting a circular built environment.
How Circular Economy Strategies Can Be Implemented in the Dwelling Renovation Design Phase
Authors: Figueirôa Ísis , do Carmo Duarte Freitas Maria , Tavares Sergio Fernando , Bragança Luís 
Published: December 2023

AbstractThe world’s largest consumer of raw materials is the construction sector, which mostly adopts the linear economy model. Several researchers make an effort to study how to realize a transition in the sector to a circular model of environmental development, applying strategies to preserve the raw resources, maintain materials in use as long as they can be, and reuse and recycle the building components. For increased circular efficiency of the construction, it is ideal to adopt strategies still in the design phase, however, most city buildings weren’t built taking this into account and have a low possibility of adaptation of spaces and disassembly of their materials and components. Dwelling renovation has a crucial role in this scenario, and this research aims to figure out how these strategies can be applied to renovation projects since there is a lack of information on how to do this, as the studies are addressed more to new buildings. Through a systematic literature review, using relevant terms, this document identified the principal’s circular economy strategies for the design phase, the dwelling spatial configuration models and the dissatisfaction of its inhabitants, and some design possibilities that can be applied to renovation projects. These findings contribute to the development of documents focused on architectural design practice.
Optimal estimation of dimension-8 neutral triple gauge couplings at the e+e− colliders
Authors: Jahedi Sahabub 
Published: December 2023

Abstract
We investigate the measurement of non-standard ZZV (V = γ, Z) couplings through Z-boson pair production at the e+e− colliders. We adopt the Standard Model Effective Field Theory (SMEFT) approach to study these anomalous neutral triple gauge couplings. There are one CP-conserving and three CP-violating dim-8 SMEFT operators that contribute to ZZV couplings. Using the optimal observable technique, the sensitivity of these new physics couplings has been estimated and compared with the latest experimental limits on dim-8 couplings at the LHC at CERN. The effect of beam polarization and correlations among CP-violating ZZV couplings are discussed. The comparison of statistical limits of new physics couplings between optimal observable technique and contemporary cut-based analysis has also been studied in detail.
Self- and non-self-DNA on hands and sleeve cuffs
Authors: Henry Léonie , Zieger Martin 
Published: December 2023

AbstractStudying DNA transfer and persistence has become increasingly important over the last decade, due to the impressive sensitivity of modern DNA detection methods in forensic genetics. To improve our understanding of background DNA that could also potentially be transferred, we analyzed the DNA composition on the outside of sleeve cuffs and sampled DNA directly from the hands of four different collaborators upon their arrival at work during 25 working days. Sampling of their hands was repeated after several hours working in our department. The shedder status of the participants, as assumed from previous internal studies, was well re-produced in the study. However, we noticed that the DNA shedding capacity could also change drastically during the day, with one participant showing a more than sixfold increase between hands sampled in the morning and hands sampled in the afternoon. As expected, poor DNA shedders carry more relative amounts of non-self-DNA on their hands than good shedders. Non-self-alleles were detected in 95% of the samples. We also observed potential effects of hand washing and the mode of transport to get to work on the DNA amount. People living with family members occasionally carried their DNA on their hands and more frequently on their sleeve cuffs. Sleeve cuffs, as being close to our hands, have a large potential to transfer DNA from one place to another, yet they have sparsely been studied as DNA transfer intermediates so far. In general, we collected consistently more DNA from the sleeve cuffs than from the hands of the participants, demonstrating their importance as potential transfer vectors. More DNA was recovered from sleeve cuffs made of synthetic fabric than from cuffs made of cotton or leather. In the afternoon, DNA from co-habitant family members could not be detected on the hands anymore and the detection of profiles from colleagues became more frequent. From two out of 100 analyzed sleeve cuffs and two out of 200 sampled hands, we established unknown major DNA profiles that would have been suitable for an entry in the national DNA database. This finding demonstrates the possibility to transfer DNA that has most likely been picked up somewhere in the public space.
Eculizumab in Shiga toxin-producing Escherichia coli hemolytic uremic syndrome: a systematic review
Authors: de Zwart Paul L. , Mueller Thomas F. , Spartà Giuseppina , Luyckx Valerie A. 
Published: December 2023

Abstract
Background
Infection-associated hemolytic uremic syndrome (IA-HUS), most often due to infection with Shiga toxin-producing bacteria, mainly affects young children. It can be acutely life-threatening, as well as cause long-term kidney and neurological morbidity. Specific treatment with proven efficacy is lacking. Since activation of the alternative complement pathway occurs in HUS, the monoclonal C5 antibody eculizumab is often used off-label once complications, e.g., seizures, occur. Eculizumab is prohibitively expensive and carries risk of infection. Its utility in IA-HUS has not been systematically studied. This systematic review aims to present, summarize, and evaluate all currently available data regarding the effect of eculizumab administration on medium- to long-term outcomes (i.e., outcomes after the acute phase, with a permanent character) in IA-HUS.

Methods
PubMed, Embase, and Web of Science were systematically searched for studies reporting the impact of eculizumab on medium- to long-term outcomes in IA-HUS. The final search occurred on March 2, 2022. Studies providing original data regarding medium- to long-term outcomes in at least 5 patients with IA-HUS, treated with at least one dose of eculizumab during the acute illness, were included. No other restrictions were imposed regarding patient population. Studies were excluded if data overlapped substantially with other studies, or if outcomes of IA-HUS patients were not reported separately. Study quality was assessed using the ROBINS-I tool for risk of bias in non-randomized studies of interventions. Data were analyzed descriptively.

Results
A total of 2944 studies were identified. Of these, 14 studies including 386 eculizumab-treated patients met inclusion criteria. All studies were observational. Shiga toxin-producing E. coli (STEC) was identified as the infectious agent in 381 of 386 patients (98.7%), effectively limiting the interpretation of the data to STEC-HUS patients. Pooling of data across studies was not possible. No study reported a statistically significant positive effect of eculizumab on any medium- to long-term outcome. Most studies were, however, subject to critical risk of bias due to confounding, as more severely ill patients received eculizumab. Three studies attempted to control for confounding through patient matching, although residual bias persisted due to matching limitations.

Discussion
Current observational evidence does not permit any conclusion regarding the impact of eculizumab in IA-HUS given critical risk of bias. Results of randomized clinical trials are eagerly awaited, as new therapeutic strategies are urgently needed to prevent long-term morbidity in these severely ill patients.

Systematic review registration number
OSF Registries, MSZY4, Registration DOI https://doi.org/10.17605/OSF.IO/MSZY4.