bluuebunny/crossref_metadata_2025_split huggingface dataset:
Immunogenic profiling of metastatic uveal melanoma discerns a potential signature related to prognosis
Authors: Wang Jian , Liu Miaomiao , Sun Jiaxing , Zhang Zifeng 
Published: January 2024

Abstract
Background
Uveal melanoma (UM) is an aggressive intraocular malignant tumor. The present study aimed to identify the key genes associated with UM metastasis and established a gene signature to analyze the relationship between the signature and prognosis and immune cell infiltration. Later, a predictive model combined with clinical variables was developed and validated.

Methods
Two UM gene expression profile chip datasets were downloaded from TCGA and GEO databases. Immune-related genes (IRGs) were obtained from IMPORT database. First, these mRNAs were intersected with IRGs, and weighted gene co-expression network analysis (WGCNA) was used to identify the co-expression of genes primarily associated with metastasis of UM. Univariate Cox regression analysis screened the genes related to prognosis. LASSO-Cox established a risk score to distinguish high-risk group and low-risk group. Then the GSEA enrichment pathway and immune cell infiltration of the two groups were compared. And combined with clinical variables, a predictive model was constructed. The time-dependent receiver operating characteristic (ROC) curve, calibration curve, and decision curve analysis (DCA) curve were used to verify the stability and accuracy of the final predictive model, and a nomogram was then drawn.

Results
The MEblack, MEpurple, and MEblue modules were significantly associated with the metastasis of UM patients (P value < 0.001, = 0.001, = 0.022, respectively). Four genes (UBXN2B, OTUD3, KAT8, LAMTOR2) were obtained by Pearson correlation analysis, weighted gene correlation network analysis (WGCNA), univariate Cox, and LASSO-Cox. And a novel prognostic risk score was established. Immune-related prognostic signature can well classify UM patients into high-risk and low-risk groups. Kaplan–Meier curve showed that the OS of high-risk patients was worse than that of low-risk patients. In addition, the risk score played an important role in evaluating the signaling pathway and immune cell infiltration of UM patients in high-risk and low-risk groups. Both the training set and validation set of the model showed good predictive accuracy in the degree of differentiation and calibration (e.g., 1-year overall survival: AUC = 0.930 (0.857–1.003)). Finally, a nomogram was established to serve in clinical practice.

Significance
UM key gene signature and prognosis predictive model might provide insights for further investigation of the pathogenesis and development of UM at the molecular level, and provide theoretical basis for determining new prognostic markers of UM and immunotherapy.
Leaf turgor loss point varies among tree species, habitats, and seasons in a bottomland hardwood forest
Authors: Eisley Alexandra M. , Wolfe Brett T. 
Published: January 2024

Abstract
Key message
Tree species in a temperate floodplain forest had leaf turgor loss point values similar to those of upland forest trees, suggesting physiological drought tolerance in this generally non-water-limited system.

Abstract
Leaf turgor loss point (TLP) is a key plant trait associated with drought tolerance. In the bottomland hardwood (BLH) forests that grow in floodplains of the southeastern USA, drought stress is generally low but may increase with climate change. To address drought tolerance among BLH trees, we measured TLP among 20 species in a BLH forest in Louisiana, USA. We tested whether (1) TLP is higher in BLH tree species than in upland temperate-zone trees; (2) lower TLP is associated with higher drought tolerance among BLH species; (3) TLP drops during the growing season within BLH trees; and (4) within species, TLP is lower in more water limited, non-flooded BLH habitats than in seasonally flooded habitats. Among BLH tree species, TLP was −2.23 ± 0.28 (mean ± SD) and, contrary to our hypothesis, weakly positively correlated with drought tolerance. Within BLH species, TLP was lower in non-flooded habitats than seasonally flooded habitats and TLP decreased between the early and late growing season, more so in the non-flooded habitat. Overall, our results show that TLP among BLH trees is relatively low and plastic for a system that is generally not water limited, which may contribute to drought tolerance in future scenarios.
Clinical performance of a glass-hybrid system in comparison with a resin composite in two-surface class II restorations: a 5-year randomised multi-centre study
Authors: Miletić Ivana , Baraba Anja , Krmek Silvana Jukić , Perić Tamara , Marković Dejan , Basso Matteo , Ozkaya Cigdem Atalayin , Kemaloglu Hande , Turkun Lezize Sebnem 
Published: January 2024

Abstract
Objective
To evaluate the 5-year clinical performance of a glass hybrid restorative system and a nano-hybrid resin composite in moderate to large two-surface class II cavities.

Materials and methods
This study was carried out by dental schools in Zagreb, Croatia; Izmir, Turkey; Belgrade, Serbia; and Milan, Italy. A total of 180 patients requiring two class-II two-surface restorations in the molars of the same jaw were recruited. The teeth were randomly restored with either a nano-hybrid resin composite (Tetric EvoCeram, Ivoclar Vivadent) or a glass-hybrid material (EQUIA Forte, GC). During the 5-year follow-up, two calibrated evaluators at each centre scored the restorations annually using the FDI-2 scoring system. The survival rates were calculated using the Kaplan–Meier method and compared using non-parametric matched pair tests (p < 0.05).

Results
There were no statistically significant differences between the overall survival and success rates of the two types of restorations (p>0.05). The success rates (FDI-2 scores 1–3) for EQUIA Forte were 81.9% (average annual failure rate: 3.9%) and 90.7% for Tetric EvoCeram (average annual failure rate: 1.9%). The survival rates (FDI-2 scores 1–4) for EQUIA Forte and Tetric EvoCeram were 94.5% and 94.4%, respectively, with an average annual failure rate of 1.1%.

Conclusions
In terms of success and survival rates, both the glass-hybrid restorative system and the nano-hybrid resin composite have been shown to perform satisfactorily.

Clinical relevance
The results of this study indicate that EQUIA Forte can be one of the therapeutic options for moderate to large two-surface class II restorations of posterior teeth.
Evaluation of strategy portfolios
Authors: Wang Anlan , Kresta Aleš , Tichý Tomáš 
Published: January 2024

AbstractPeople usually create a portfolio in order to diversify the risk coming from individual investments. To get a high yield with a good level of diversification, investors usually seek professional advice from portfolio managers. However, the true performance of an optimized portfolio usually depends on the correctness of the estimates of the distribution of future returns, which is often a matter of luck rather than skill. Thus, the optimization models may not be better than randomly selected portfolios. Our aim is to find how the so-called strategy portfolios, i.e., portfolios obtained by some decision optimized for a long-run horizon, perform compared to a benchmark, namely, a random investment, under specific market conditions. For this purpose, we evaluate several portfolio strategies over two periods of crisis: the subprime mortgage crisis and the Covid-19 pandemic, as well as run a moving window analysis over a longer horizon. In each case, the results are compared with the performance of random-weight portfolios. We find that if the strategy is minimization, the portfolios perform well; however, for the maximization of the objectives, the results are rather mixed.
Dust captured by a canopy and individual leaves of trees in the tropical mixed deciduous forest: Magnitude and influencing factors
Authors: Bridhikitti Arika , Khumphokha Pawaporn , Wanitha Wantanan , Prasopsin Suphat 
Published: January 2024

AbstractForest tree leaves play a significant role in air purification, but forest fires could offset the dust sink role. This study aims to assess the functions of the forest in atmospheric dust sink and source and assess the dust capturing capacity of individual leaves of various tree species in the tropical mixed deciduous forest in the dry season (November 21, 2021, to January 23, 2022), along with its influencing factors—climatic variables, environmental variables, and leaf morphology. The result shows that the downward flux or the forest dust sink role was predominant midday when air–mass turbulence played a role. Nonetheless, net mass PM1 and PM10 concentration trapped by the forest canopy was low, 0.79 and 2.24 µg m−3, respectively. For PM2.5, forest fires could outrun the PM2.5 sink role for the entire dry season. Considering the individual tree leave, maximum dust capturing capacities for the forest trees ranged from 0.95 to 5.197 g m−2. Leaf dust capturing capacity was enhanced under cold and dry weather, strong winds, and for trees with defoliated or irregular shape. Leaf/leaflet enhancing the dust capturing capacity exhibited large size; either thick and leathery texture (Coriaceous) or thin, semi-translucent, membrane-like texture (Membranaceous); indumentum top being short, stiff trichomes (Scabrous); or indumentum bottom surface being densely short, soft trichomes (Tomentose). The various dust capturing dynamics among tree species could benefit dust capturing by the forests in the dry season.
Seismic pounding of adjacent buildings considering torsional effects
Authors: Ozer Esra 
Published: January 2024

AbstractThis study aims to evaluate pounding effects in fixed-base models by considering torsional irregularity. For this purpose, 8 different adjacent building combinations were created by using 3-dimensional 5- and 9-story building models. In adjacent building models, the most critical situation was determined by evaluating the gap distance, different sequences of the same building models and regular or irregular plan view and if the structures are irregular, their eccentricity cases relative to each other. Nonlinear behavior of structural elements was taken into account for examine the change in the seismic behavior of structural elements due to pounding and torsion effects. The nonlinear time history analysis of the adjacent models was performed for 11 pairs of spectrum compatible ground motion recordings in the SAP2000 program. The results of 176 different analyzes show that the displacement demand, interstory drift ratio, damage ratio and torsional irregularity coefficient values tend to increase in general with the combined effects of pounding and torsion. The absolute maximum and most critical values of the relevant parameters were calculated in irregular structures with pounding where the eccentricity of buildings is in the same direction and same side. In addition, the large standard deviation of the result values according to the ground motion records indicates that care should be taken in choosing the number of ground motion records.
Sibling Relationships in Families of Autistic and Typical Children: Similarities and Differences in the Perspectives of Siblings and Mothers
Authors: Rum Yonat , Zachor Ditza A. , Armony Yael , Daniel Ella , Dromi Esther 
Published: January 2024

Abstract
This study investigates mothers' and siblings' perspectives regarding similarities and differences in siblingships with and without autism. Twenty-nine typical children (M
age = 8.78 years, SD = 2.05) whose younger siblings have a diagnosis of autism and their mothers constituted the ‘autism group.’ Forty-six typical children (M
age = 9.12 years, SD = 2.06) with younger typical siblings and their mothers constituted the ‘typical group’. Children and mothers completed the Sibling Relationship Questionnaires and were interviewed. Children's reports illustrated similarities in sibling relationships across groups, with no between-group differences in overall warmth, conflict, rivalry, or relative power in the sibling relationship. Mothers of autistic children reported their children to have less warmth and closeness (F
(1,72) = 5.63, p = .02, η2 = .073) and less conflict (F
(1,72) = 6.66, p = .012, η
2 = .085) with their siblings than mothers of typical children. More disagreement was found between mothers and children in the autism group than in the typical group. Mothers and children reported less intimacy and less quarreling between the siblings in the autism group than in the typical group. The qualitative analysis suggests that siblings focused on the present experience, while mothers also referred to processes in the sibling relationship. Interviewees in the autism group referred to various specificities in the siblingships without explicitly using the term “autism”. The findings highlight a typical-like experience for siblings of autistic children. At the same time, mothers' perspectives emphasize differences and challenges in siblingships, reporting a pattern of decreased involvement. It is important to consider both perspectives in research and clinical work with families of autistic children.
Social Connections and Future Horizons: Socioemotional Selectivity Among Midlife and Older Adults in Aotearoa/New Zealand During COVID-19
Authors: Newton Nicky J. , Breheny Mary , Stephens Christine 
Published: January 2024

AbstractThe current study uses socioemotional selectivity theory (SST; Carstensen in Psychology and Aging. 7(3):331–338,1992,10.1037/0882-7974.7.3.331) as a framework to examine the experiences of older adults during COVID-19 in Aotearoa/New Zealand. SST posits that when time horizons are perceived as limited—such as with increasing age, or during times of medical uncertainty—people selectively focus on spending time with emotionally close others and in personally fulfilling activities. This may be the case particularly when uncertainty is experienced by older people. Aotearoa/New Zealand instigated an elimination strategy early in the pandemic (prior to widespread vaccine availability), employing a series of lockdowns that further challenged older adults’ perceptions of future horizons, their ability to maintain social connections with loved ones, and engagement in pleasurable activities. This study used thematic analysis to analyze existing qualitative COVID-19-related data drawn from the experiences of 510 older adults who participated in the 2021 Health, Work, and Retirement study (HWR). Participants ranged in age from 56 to 87 (Mage = 69.73); 15.9% identified as Māori, and 76.2% identified as female. Two broad themes were revealed: Social Connection and Anticipating the Future. Although most participants expressed comparatively more positive than negative experiences, some also expressed frustration and anxiety about health directive-related divisions in relationships, and the inability to share in important life events (such as weddings, births, and funerals). Findings highlight the complex impact of COVID-19 on older adults’ perceptions of time horizons, and the opportunities presented by the pandemic for reassessment of social relationships and activities.
The risk of perinatal and cardiometabolic complications in pregnancies conceived by medically assisted reproduction
Authors: Vilda Dovile , Sutton Elizabeth F. , Kothamasu Venkata Sai Sahithi , Clisham Paul R. , Gambala Cecilia T. , Harville Emily W. 
Published: January 2024

Abstract
Purpose
To examine the impact of medically assisted fertility treatments on the risk of developing perinatal and cardiometabolic complications during pregnancy and in-hospital deliveries.

Methods
We conducted a retrospective cohort study using medical health records of deliveries occurring in 2016–2022 at a women’s specialty hospital in a southern state of the Unites States (US). Pregnancies achieved using medically assisted reproductive (MAR) techniques were compared with unassisted pregnancies using propensity score matching (PSM), based on demographic, preexisting health, and reproductive factors. Study outcomes included cesarean delivery, gestational diabetes mellitus (GDM), hypertensive disorders of pregnancy (HDP), delivery complications, and postpartum readmission. We used Poisson regression with robust standard errors to generate risk ratios (RRs) and 95% confidence intervals (CIs) for all study outcomes.

Results
Among 57,354 deliveries, 586 (1.02%) pregnancies were achieved using MAR and 56,768 (98.98%) were unassisted (“non-MAR”). Compared to the non-MAR group, MAR pregnancies had significantly higher prevalence of all study outcomes, including GDM (15.9% vs. 11.2%, p < 0.001), HDP (28.2% vs. 21.1%, p < 0.001), cesarean delivery (56.1% vs. 34.6%, p < 0.001), delivery complications (10.9% vs. 6.8%, p = 0.03), and postpartum readmission (4.3% vs. 2.7%, p = 0.02). In a PSM sample of 584 MAR and 1,727 unassisted pregnancies, MAR was associated with an increased risk of cesarean delivery (RR = 1.11, 95% CI = 1.01–1.22); whereas IVF was associated with an increased risk of cesarean delivery (RR = 1.15, 95% CI = 1.03–1.28) and delivery complications (RR = 1.44, 95% CI = 1.04–2.01).

Conclusions
Women who conceived with MAR were at increased risk of cesarean deliveries, and those who conceived with IVF were additionally at risk of delivery complications.
Using National Incident-Based Reporting System Data to Explore Animal Cruelty Incidents that Occur with Intimate Partner and Family Violence: A Brief Report
Authors: Addington Lynn A. , Randour Mary Lou 
Published: January 2024

Abstract
Purpose
This brief report extends what is known about “the link” between animal cruelty and intimate partner violence (IPV) and family violence (FV). Specifically, it uses animal cruelty data from the Federal Bureau of Investigation’s National Incident-Based Reporting System (NIBRS) to explore characteristics of incidents where animal cruelty and IPV or FV occur together.

Methods
This exploratory study analyzes 278 animal cruelty incidents that occurred with IPV or FV from the 2020 NIBRS data using descriptive and bivariate analyses.

Results
Findings from the NIBRS animal cruelty data suggest the importance of parsing out specific intimate and family relationships. While these patterns are similar to IPV and FV that occur with crimes outside of animal cruelty, previous research on the link has not examined these relationships. This study also found the majority of animal cruelty incidents that occur with IPV or FV end in an arrest. No previous work has identified arrest patterns in these cases.

Conclusions
Although exploratory, this study highlights the value of NIBRS animal cruelty data and the opportunity to gain insights at the incident level of details that were previously unavailable from other animal cruelty studies that consider IPV and FV. This study provides a foundation for future research that can inform theoretical development and prevention efforts related to the link.
Solvable Stationary Non Equilibrium States
Authors: Carinci G. , Franceschini C. , Gabrielli D. , Giardinà C. , Tsagkarogiannis D. 
Published: January 2024

AbstractWe consider the one dimensional boundary driven harmonic model and its continuous version, both introduced in (Frassek et al. in J Stat Phys 180: 135–171, 2020). By combining duality and integrability the authors of (Frassek and Giardiná in J Math Phys 63: 103301, 2022) obtained the invariant measures in a combinatorial representation. Here we give an integral representation of the invariant measures which turns out to be a convex combination of inhomogeneous product of geometric distributions for the discrete model and a convex combination of inhomogeneous product of exponential distributions for the continuous one. The mean values of the geometric and of the exponential variables are distributed according to the order statistics of i.i.d. uniform random variables on a suitable interval fixed by the boundary sources. The result is obtained solving exactly the stationary condition written in terms of the joint generating function. The method has an interest in itself and can be generalized to study other models. We briefly discuss some applications.
A novel 3D train–bridge interaction model for monorail system considering nonlinear wheel-track slipping behavior
Authors: Yang Yun , He Qinglie , Cai Chengbiao , Zhu Shengyang , Zhai Wanming 
Published: January 2024

AbstractVariable speed operation of the train cause easily the wheel-track slipping phenomenon, inducing strong nonlinear dynamic behavior of the suspended monorail train and bridge system (SMTBS), especially under an insufficient wheel-track friction coefficient. To investigate the coupled vibration features of the SMTBS under variable speed conditions, a novel 3D train–bridge interaction model for the monorail system considering nonlinear wheel-track slipping behavior is developed. Firstly, based on the D’Alembert principle, the vibration equations of the vehicle subsystem are derived by adequately considering the nonlinear interactive behavior among the vehicle components. Then, a high-efficiency modeling method for the large-scale bridge subsystem is proposed based on the component mode synthesis (CMS) method. The vehicle and bridge subsystems are coupled with a spatial wheel-track interaction model considering the nonlinear wheel-track sliding behavior. Furtherly, by a comprehensive comparison with the field test data, the effectiveness of the proposed method is verified, as well as the reasonable modal truncation frequencies of the bridge subsystem are determined. On this basis, the dynamics performances of the SMTBS are evaluated under different initial braking speeds and wheel-track interfacial adhesion conditions; besides, the nonlinear wheel-track slipping characteristics and their influences on the vehicle–bridge interaction are also revealed. The analysis results indicate that the proposed model is reliable for investigating the time-varying dynamic features of SMTBS under variable train speeds. Both the axle load transfer phenomenon and longitudinal slip of the driving tire would be easy to appear under the braking condition, which would significantly increase the longitudinal vehicle–bridge dynamic responses. To ensure a good vehicle–bridge dynamics performance, it is suggested that the wheel-track interfacial friction coefficient is larger than 0.35.
Military directors and stock price informativeness: What's all the fuss about?
Authors: Nawaz Tasawar , Nawaz Tahseen 
Published: January 2024

AbstractExploiting a unique hand-built dataset, belonging to non-financial firms, operating in an emerging economy, this study, first of its kind, reports that stock prices of firms with military-experienced board of directors reflect more firm specific information after controlling for board attributes, agent heterogeneity and firm level variation. The results robust to alternative specifications of informativeness and military director proxy support the notion that military-trained directors may enhance transparency in public listed companies and encourage the incorporation of more firm-specific information into stock prices. Further analysis suggests that military directors may enfeeble CEO–board nexus and settle the directional variations at the corporate board level: military directors bring discipline in the board room that translates into rigorous CEO monitoring and improved corporate governance quality.