bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE ROLE OF SIMULATION TRAINING FOR TEACHING (IN TEACHING) ANESTHESIOLOGIST INTERNS: A TWO-WAY SURVEY
Authors: BIELKA K. , KUCHYN YU. , POSTERNAK G , SAVCHENKO B. 
Published: October 2023

Resume. In the modern system of training intern anesthesiologists, simulation training is becoming an increasingly common tool for achieving educational goals. The simulation ensures the acquisition of professional competencies without the risk of harm to the patient and enables teachers to objectively assess the level of professional training of each intern. There is a growing need to review traditional approaches to the interaction between a teacher and an intern with the increasing use of simulation technologies.
The purpose of the study was to determine the role of simulation training in the teaching of anesthesiologist interns.
Materials and method. A prospective audit was conducted at the Department of Surgery, Anesthesiology and Intensive Care of the O.O. Bogomolets National Medical University in the period from April to June 2023. Interns of the 2nd year of training in 2023 in the speciality «Anesthesiology and intensive care» were trained in a 1-day simulation training «Critical incidents during anaesthesia". We examine data (lower-level outcomes) assessing the role of simulation training on learning outcomes and willingness to work independently from the perspective of interns and faculty using an anonymous questionnaire at the end of the training.
Results: the audit included 36 responses from interns and 10 from teachers. Many intern doctors noted an increase in their motivation to study, achievement of educational goals and correction of errors as a result of debriefing thanks to the conducted simulation training. Intern doctors noted that such training was very close to real conditions, it increased confidence in working with patients and readiness for emergencies, helped identify knowledge gaps and was more effective compared to traditional training (lectures, seminars). The results of the teachers' survey confirm the importance of simulation training as an effective means of training interns, which ensures the achievement of educational goals without risks for patients, accelerates the process of acquisition of competencies by learners, increases their motivation to study and objectively reflects the level of skills and knowledge of interns.
Conclusions. Our research has proven that simulation training should be a mandatory component of the training program of the clinical internship in the speciality «Anesthesiology and intensive care» with an increase in their share in the training program of specialists. Creating conditions of mutual trust between interns and teachers is the key to the social mission of ensuring the quality of postgraduate education. Conducting a debriefing after working out each simulation scenario lays the foundation for the formation of critical thinking in future doctors and helps to avoid mistakes in real clinical practice.
The role of systematic simulation training at the postgraduate level to improve outcomes in real clinical practice may be the subject of further research.
Science virale : comment la COVID-19 a changé la représentation médiatique de la science
Authors: Claveau François , Roy Jean-Hugues , Santerre Olivier 
Published: October 2023

Background: Media representations of science have changed little over the past few decades, despite numerous calls for their enrichment.Analysis: The shock caused by the COVID-19 pandemic has changed how the media represent science. This computational analysis of two large samples (news articles and Facebook posts) from French language news media in Canada describes and quantifies these changes.Conclusions and implications: Science has been more present in the media. It has generated more public interactions. It has become more associated with political regulation and more explicitly uncertain. Indeed, the authors measure a 20 to 25 percent shift on these variables.
The Components that Constitute the Modern Bow
Authors: GÜLER Murat Ufuk 
Published: October 2023

Considering the musician-luthier relationship, it is important that two professions that cannot be independent of each other meet in a joint jargon. The lack of common terminology is felt mostly in instruments that have passed into our music from the West.
It would not be wrong to say that some abstract concepts used when talking about a subject related to an instrument are extensively adopted in our language. For example, the definition of "metallic sound" is understandable to most music professionals. On the other hand, the lack of a common terminology regarding the structure of instruments is observed, and it is noticed that there are many issues that need to be studied in this field.
In this study, in which we discuss the instruments that we use to get sound from the violin family instruments and which we define as "Modern Bow" or simply "Bow", we aim to contribute to the terminology by introducing the parts of the bow, as well as by offering Turkish equivalents for these parts.
AFGAN GÖÇMENLERİN EĞİTİME ERİŞİMDE KARŞILAŞTIKLARI SORUNLAR: VAN VE MEŞHED ÖRNEĞİ
Authors: YILMAZ ASLAN Hatice 
Published: October 2023

Eğitim, her toplumun gelişmesinde ve ilerlemesinde önemli bir faktördür. Ancak göçmenler için eğitim, birçok sorunla karşılaşılan önemli bir konudur. Göç eden insanların kentsel uyum sorunu yaşamalarında eğitim seviyesinin düşüklüğü büyük bir rol oynamaktadır. Göçmenler, göç ettikleri ülkenin dilini ve kültürünü öğrenmekte zorlanabilmektedirler. Ayrıca göçmen çocuklarının okula gitmesi, öğrenim hayatlarını sürdürebilmeleri de göçmenler için zorluklarla dolu bir süreç olmaktadır. Göçmenlerin eğitimde en çok yaşadığı sorunlar dil bariyeri, kültür farklılıkları, önyargılar ve finansal zorluklardır. Göç edenler, varış ülkelerinin dilini genelde bilmedikleri eğitim sistemi içinde başarısızlık ve uyum sorunlarına neden olabilmektedir. Kültür farklılıkları da göçmenlerin eğitim sürecinde karşılaştığı diğer bir sorundur. Göçmenlerin yeni ülkenin kültürüne uyum sağlaması ve kendilerini buna adapte etmeleri gerekmektedir. Bu süreç, özellikle farklı kültürler arasındaki çatışmalara sebebiyet vermektedir.
Bu çalışmada Afgan göçmenlerin en fazla göç ettiği ülkelerdeki şehirlerden olan Van ve Meşhed şehirlerinde göçmenlerin kentsel uyum süreçlerinde eğitime erişimleri noktasında karşılaştıkları problemler karşılaştırmalı olarak incelenmiştir. Çalışmamızda her iki kentteki ilköğretim ve lise öğrencilerinin okul ve eğitim süreçlerinde karşılaştıkları eğitim ve uyum problemleri, ilgili sorular çerçevesinde elde edilen veriler ışığında detaylı bir şekilde analiz edilmiştir. Tez çalışmamızda yaş sınırı olduğundan 17 yaş altı çocukların eğitim sorunları ailelerle yapılan derinlemesine görüşmeler çerçevesinde elde edilmiştir. 17 ve üstü öğrencilerle bizzat görüşülmüştür. Göçmenlerin özellikle sosyal ve kültürel olarak karşılaştıkları problemleri eğitimde de (özellikle Meşhed Kentinde) fazlasıyla yaşadıkları görülmüştür. Ayrıca yine finansal ve dil sorunu da eğitim konusunda karşılaşılan en önemli problemler olarak karşımıza çıkmıştır. Önyargılar ve ayrımcılık da göçmenlerin eğitimde karşılaştığı sorunlar arasındadır. Bu durum, okulda sosyal izolasyona ve dışlanmaya neden olabilmektedir.
Enumerations of families closed under finite differences
Authors: Greenberg Noam , Harrison-Trainor Matthew , Miller Joseph S. , Turetsky Dan 
Published: October 2023

Slaman and Wehner independently built a family of sets with the property that every non-computable degree can compute an enumeration of the family, but there is no computable enumeration of the family. We call such a family a Slaman–Wehner family. The original Slaman–Wehner argument relies on all sets in the family constructed being finite, and in particular, it diagonalizes against computably enumerated families using only finite differences. In this paper we ask whether this is a necessary feature, that is, whether there is a Slaman–Wehner family closed under finite differences. This question remains open but we obtain a number of interesting partial results which can be interpreted as saying that the question is quite hard. First of all, no Slaman–Wehner family closed under finite differences can contain a finite set, and the enumeration of the family from a non-computable degree cannot be uniform (whereas, in the Slaman–Wehner construction, it is uniform). On the other hand, we build the following examples of families closed under finite differences which show the impossibility of several natural attempts to show that no Slaman–Wehner family exists: (1) a family that can be enumerated by every non-low degree, but not by any low degree; (2) a family that can be enumerated by any set in a given uniform list of c.e. sets, but which cannot be enumerated computably; and (3) a family that can be enumerated by a given [Formula: see text] set, but which cannot be computably enumerated.
Toxoplasmosis Examination With Anti-Toxo IgM And IgG Results In Petshop Staff
Authors: Pratama Sandi Setya , Kumoro Adhi 
Published: October 2023

Toxoplasmosis is an infection caused by a single-celled parasite called Toxoplasma gondii. Infection is most commonly acquired from contact with cats and their feces or raw or undercooked meat. There are several risk factors that favor the occurrence of this infection including the presence of cats in the residence, cleaning of pet litter boxes, hand washing habits and consumption of raw or undercooked food. Petshop is a retail business that sells a variety of pets and also sells pet food, accessories, animal care and maintenance. The purpose of this study was to determine the exposure to toxoplasmosis with the results of Toxoplasma gondii IgG antibody examination and Toxoplasma gondii IgM antibody in petshop staff.This study is a descriptive study using cross sectional method with 25 respondents from petshop staff. The test method for toxoplasmosis detection used was Rapid (Immunochromatography). The data analysis technique used was univariate analysis to determine the percentage of seropositive results of Toxoplasma gondii IgG antibodies and Toxoplasma gondii IgM antibodies. Based on the results of the study obtained data 11 respondents seropositive anti-toxo IgG, 14 respondents did not have anti-toxo IgG and anti-toxo IgM and there were no respondents with positive anti-toxo IgM in Petshop officers. Therefore it can be concluded that 11 out of 25 respondents have been infected with Toxoplasma gondii.
Modigiz Application as an Educational Media for Overweight Teenagers
Authors: Ningsih Retno Wahyu , Darni Joyeti , Surya Aji Ramadan Wibi 
Published: October 2023

Background: Android mobile applications about nutrition and health are starting to be developed, but only a few develop mobile applications with a discussion of overweight adolescents. Android media with exciting features can be an alternative to increase adolescents' awareness of the problem of obesity.Research Methods: Development of an Android mobile application named "Modigiz," which stands for mobile obesity diet nutrition. The application is developed using the agile software development method and uses its development technology, namely Android Studio, Android SDK, Kotlin, Android Jetpack Library, Github, Figma, and Canva.Research Result: The Modigiz application implements the principle of quick feedback for application users. Users can find nutritional status information about each feature display, and there is feedback for consultations between users and the team via WhatsApp no.Conclusion: The Modigiz application was developed for overweight adolescents to monitor their nutritional status and manage their diet independently. In addition, this application also provides nutrition and health information for users, so it is hoped that it can encourage healthy behavior habits and implement balanced nutrition.
La apelación y la aplicación de la garantía ¨non reformatio in peius¨ en la legislación ecuatoriana
Authors: Jiménez Lojano Jessica Fernanda , Zamora Ana Fabiola 
Published: October 2023

Introducción: La incertidumbre del estado del procesado al establecer un recurso de apelación dentro del sistema procesal Ecuatoriano, se deriva de la mala aplicación e inobservancia al debido proceso en todas las instancias del sistema penal, esto ha llevado que los derechos del recurrente sean vulnerados ante la inobservancia al principio de non reformatio in peius especialmente en segunda instancia, por lo que el objetivo de la investigación fue analizar la aplicación de la garantía de non reformatio in peius, a través de la ley, derecho comparado, jurisprudencia y fundamentación teórica, para prevenir vulneración de principios procesales en segunda instancia del proceso penal evitando infringir el debido proceso, seguridad jurídica y el derecho a recurrir. Metodología: El nivel de investigación fue el descriptivo tomado desde el enfoque cualitativo, empleando la recopilación de información de diferentes bases de datos científicas y jurisprudenciales, publicadas en los últimos cinco años, siguiendo el mismo hilo se incluyó el respectivo análisis jurídico de los cuerpos normativos vigentes en el Ecuador, se aplicó el derecho comparado respecto a la garantía de la non reformatio in peius en relación con otros países con un similar sistema judicial. Conclusión: Como conclusión del presente trabajo de investigación se determinó que la garantía del non reformatio in peius no fue aplicado por los jueces de segunda instancia, por cuanto existen contraposiciones de criterios respecto a su aplicación al no tener positivada esta garantía en el Código Orgánico Integral Penal. Área de estudio general: Derecho. Área de estudio específica: Derecho procesal.
Rancang Bangun Smart door lock Menggunakan Fingerprint dan Mikrokontroler Arduino Uno di BMT NU Jangkar
Authors: Rohman Ahmad Zainur , Sunardi  , Munazilin Akhlis 
Published: October 2023

Banyak permasalahan yang mengancam keamanan sebuah rungan, seperti pencurian, pembobolan dan lain sebagainya. Keamanan sebuah ruangan adalah hal penting yang memberikan dampak besar dan sumber daya penting di dalamnya. Sistem keamanan yang lemah pada ruangan tempat produk disimpan memberikan potensi terbukanya pintuagi orang lain yang tidak memenuhi syarat untuk mengambil barang-barang di ruangan tersebut dan khawatir akan kemungkinan kunci ruangan tersebut hilang. Oleh karena itu pentingnya meningkatkan kualitas keamanan pada ruangan sangat penting kita lakukan, salah satu upaya meningkatkan kualitas keamanan adalah merancang dan membangun smart door lock meggunakan fingerprint dan mikrokontroler Arduino uno yang diharapkan mampu untuk meningkatkan kualitas keamanan pada suatu ruangan dan untuk memfilter siapa saja yang boleh masuk ke ruangan brankas tersebut. Untuk membuka pintu pada rungan sebuah fingerprint yang dijadikan alat pemindai sidik jari sehingga selenoid bisa terbuka 3 detik dengan ditandai bunyi buzzer 2 kali dengan cepat jika sidik jari cocok dan tertutup kembali, kemudian sistem ini juga dapat menginformasikan bahwa sidik jari yang di tempelkan ke sensor fingerprint belum terdaftar maka selenoid door lock tidak terbuka dan buzzer akan berbunyi panjang.
Epithelial–mesenchymal transition: an organizing principle of mammalian regeneration
Authors: Bedelbaeva Kamila , Cameron Benjamin , Latella John , Aslanukov Azamat , Gourevitch Dmitri , Davuluri Ramana , Heber-Katz Ellen 
Published: October 2023

Introduction: The MRL mouse strain is one of the few examples of a mammal capable of healing appendage wounds by regeneration, a process that begins with the formation of a blastema, a structure containing de-differentiating mesenchymal cells. HIF-1α expression in the nascent MRL wound site blastema is one of the earliest identified events and is sufficient to initiate the complete regenerative program. However, HIF-1α regulates many cellular processes modulating the expression of hundreds of genes. A later signal event is the absence of a functional G1 checkpoint, leading to G2 cell cycle arrest with increased cellular DNA but little cell division observed in the blastema. This lack of mitosis in MRL blastema cells is also a hallmark of regeneration in classical invertebrate and vertebrate regenerators such as planaria, hydra, and newt.Results and discussion: Here, we explore the cellular events occurring between HIF-1α upregulation and its regulation of the genes involved in G2 arrest (EVI-5, γH3, Wnt5a, and ROR2), and identify epithelial–mesenchymal transition (EMT) (Twist and Slug) and chromatin remodeling (EZH-2 and H3K27me3) as key intermediary processes. The locus of these cellular events is highly regionalized within the blastema, occurring in the same cells as determined by double staining by immunohistochemistry and FACS analysis, and appears as EMT and chromatin remodeling, followed by G2 arrest determined by kinetic expression studies.
Impact of organophosphate pesticides exposure on human semen parameters and testosterone: a systematic review and meta-analysis
Authors: Hamed Moses A. , Akhigbe Tunmise M. , Adeogun Adetomiwa E. , Adesoye Oluwatosin B. , Akhigbe Roland E. 
Published: October 2023

BackgroundOrganophosphate (OP) pesticides have been associated with a decline in semen quality, although there are still considerable arguments about the magnitude of the association.ObjectiveThis study provides a systematic review and meta-analysis of the impacts of OP pesticides on semen quality and male reproductive hormones.MethodsThis study was conducted according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) protocols. Strategic search was conducted using combined text words as search terms. The eligibility criteria were developed based on Population, Exposure, Comparator, Outcome, and Study designs (PECOS) framework. Relevant data were extracted, risk of bias was evaluated by The Office of Health Assessment and Translation (OHAT) tool, and certainty of evidence was assessed by the Grading of Recommendations Assessment, Development and Evaluation (GRADE) Working Group guidelines. Quantitative meta-analysis was performed by using Review Manager.ResultsA total of 766 male subjects (349 exposed to OP pesticides and 417 unexposed controls) were included in the meta-analysis. There was no significant difference in the ejaculate volume, seminal fluid volume, sperm multiple anomaly index, sperm, and leukocytes levels of the OP-exposed subjects compared to the control. In addition, OP pesticides exposure did not significantly affect serum concentrations of FSH, LH, and testosterone in subjects who were exposed to OP pesticides compared to their unexposed counterparts. However, we found a significant reduction in the sperm count, sperm concentration, progressive sperm motility, total sperm motility, and normal sperm morphology of OP pesticides-exposed subjects compared to the unexposed subjects. However, after subtype and sensitivity analyses, exposure to OP pesticides did not reduce sperm count. Also, after sensitivity analysis, OP pesticides exposure did not alter progressive sperm motility.ConclusionThis study demonstrates that OP pesticides exposure reduced sperm count, concentration, total and progressive motility, and normal sperm morphology, possibly via a testosterone-independent mechanism.
Expression of genes and enzymes involved in ovarian steroidogenesis in relation to human follicular development
Authors: Zheng Mengxue , Andersen Claus Yding , Rasmussen Frida Roikjer , Cadenas Jesús , Christensen Søren Tvorup , Mamsen Linn Salto 
Published: October 2023

IntroductionGranulosa cells (GCs) and theca cells (TCs) play a pivotal role in human ovarian steroidogenesis, facilitating the conversion of cholesterol into sex steroids that regulate normal reproductive function. This study aims to explore the expression patterns of key enzymes that govern human ovarian steroidogenesis throughout follicle development, employing both genomic and immunological methodologies. MethodsFollicles and GCs obtained from women undergoing ovarian tissue cryopreservation (OTC) and in vitro fertilisation treatment were utilized. Gene expression data were obtained from a Chinese study using RNA sequencing and from microarray data generated in our laboratory to comprehensively analyse gene expression profiles across distinct stages of follicular development. To corroborate the localisation of key enzymes within GCs and TCs, immunohistochemistry analyses utilizing colourimetric and fluorescent techniques were conducted.ResultsSteroidogenesis-related enzymes displayed low gene expression levels during early follicle development. However, a notable upregulation of HSD3B2 was observed in GCs as follicles progressed to the antral/preovulatory stage, confirmed consistently using both microarray and RNA sequencing methodologies. Furthermore, immunohistochemical analyses effectively demonstrated that HSD3B2 were not only expressed in GCs, but co-localised with CYP17A1 within a specific subset of TCs surrounding human small antral follicles. Contributing to an enhanced progesterone production during the second half of the follicular phase was a significant upregulation of CYB5A in both microarray and RNA-seq datasets as follicles transition from the antral stage to the pre-ovulatory stage. Moreover, an augmented expression of DHCR24 and LDLR in both types of data, along with HMGCR expression expression in the microarray data, indicates increased substrate availability for ovarian steroidogenesis.DiscussionThis study confirms and extends that GCs gradually augment expression of HSD3B2 thereby enhancing their capacity for progesterone synthesis as follicles reach the size of selection at around 10 mm in diameter. This is supported by the expression CYB5A and possibly augmented availability of steroid precursors. A subset of TCs exhibit concurrent expression of CYP17A1 and HSD3B2, collectively contributing to the synthesis of 17-hydroxyprogesterone. These data significantly enhance our understanding of the dynamic regulation of progesterone throughout the process of follicular development.