bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Joys and Stresses of Social Relationships and the Effect on Resiliency During the COVID-19 Pandemic: A National Survey of U.S. Older Adults
Authors: Westrick Ashly C , Kobayashi Lindsay C , Kirch Matthias , Singer Dianne , Malani Preeti N , Kullgren Jeffrey T , Solway Erica , Finlay Jessica M 
Published: October 2023

Abstract

Background and Objectives
The coronavirus disease 2019 pandemic placed unprecedented stress on older adults. Resiliency could mitigate deleterious effects of pandemic stressors. We described trends in resilience among U.S. adults aged 50–80 years approximately one and a half years after the onset of the pandemic, compared with before the pandemic, and evaluated associations between relationships and resilience.

Research Design and Methods
Data were from the National Poll on Healthy Aging (N = 2,100) in August 2021. Respondents rated their resiliency as compared with before the pandemic (more, about the same, or less) and different types of relationships (spouse/partner, friends, and neighbors) as sources of joy and/or stress during the pandemic (a lot, some, very little, and not at all). Multinomial logistic regressions (complete-case analysis) estimated the relationships between each joyful and stressful relationships and resiliency.

Results
Most participants reported feeling as resilient as before the pandemic (70.6%) with 14.5% feeling less resilient. More women than men felt less resilient than before the pandemic (16.7% vs 12.8%, p = .006). Feeling a lot of stress from one’s spouse or neighbors was associated with increased likelihood of feeling less resilient than before the pandemic (odds ratio [OR] = 3.7; 95% confidence interval [CI]: 1.8, 7.7 and OR = 4.5; 95% CI: 1.5, 13.9, respectively), which was stronger among women (OR = 15.1; 95% CI: 4.8, 45.6) than men (OR = 1.03; 95% CI: 0.4, 2.7).

Discussion and Implications
Social relationships may have been more important for women than for men in supporting resiliency during the pandemic. Understanding patterns of resiliency can help to inform policymaking and support the well-being of older adults.
Adjoint-based data assimilation for reconstruction of thermal convection in a highly viscous fluid from surface velocity and temperature snapshots
Authors: Nakao Atsushi , Kuwatani Tatsu , Ito Shin-ichi , Nagao Hiromichi 
Published: October 2023

SUMMARY
It is a general problem in geoscience to estimate the time-series of velocity and temperature fields for a fluid based on limited observations, such as the flow velocity at the fluid surface and/or a temperature snapshot after flow. In this study, an adjoint-based data assimilation method (also known as 4-D variational data assimilation) was used to reconstruct the thermal convection in a highly viscous fluid (e.g. Earth’s mantle) to investigate which observations constrain the thermal convection and how accurately the convection can be reconstructed for different wavelengths. The data assimilated to the adjoint-based model were generated synthetically from forward models with convecting cells of different length-scales. Based on the surface velocity and temperature snapshot, our simulations successfully reconstructed thermal convection over 50 Myr in the case that the wavelength of the convective cells is sufficiently large. We obtained two main results from this parametric study. (1) When we only considered instantaneous thermal structure fitting in the cost function, the convection reconstruction tended to fail. However, there are some cases where the laminar thermal convection can be reconstructed by assimilating only the velocity along the fluid surface. (2) There is a limit to the reconstruction of thermal convection in the case that the convecting cells are small (∼1000 km for a 50 Myr reconstruction). We propose that (1) is related to the balance of forces due to the thermal buoyancy and viscous stress around the thermal anomalies and (2) is related to how information is preserved (i.e. how the previous thermal structure is maintained in the observable state throughout the convection process). The results enable the use of geological records to estimate time-series of velocity and temperature in Earth’s deep interior, even though the records may only contain information from shallow parts of Earth.
Mental health promotion practice in Aotearoa New Zealand: findings from a qualitative study
Authors: Craik Brooke , Egan Richard , Kewene Francis , Morgaine Kate C 
Published: October 2023

Abstract
Mental health promotion (MHP) is integral to improving the overall health and well being of individuals, communities, and populations. However, knowledge and reporting about MHP which occurs throughout Aotearoa New Zealand (NZ) is limited. This article reports findings from a qualitative study that sought to understand NZ health promotion practitioners’ (HPPs) MHP practice. Semi-structured interviews were undertaken with 15 HPPs employed at various health promotion organizations. Thematic analysis of interview transcripts identified three key themes. Two themes (planning and evaluation) related to practice directly and included various subthemes: needs assessment; principles/approaches/frameworks; operationalizing equity and te Tiriti o Waitangi; collaborative approaches; planning for evaluation; process evaluation domination; and evaluation challenges. The third theme related to the context of practice and encompassed various system influences restricting HPPs from practising as they wished. These were represented in four subthemes: contractual agreements; field fragmentation; in the shadows of mental ill-health and workforce capacity. Study findings highlight several opportunities to improve MHP practice in NZ. Most pertinently, the need for system-level action to address the factors restricting HPPs’ practice.
Dalbavancin plasma concentrations in 133 patients: a PK/PD observational study
Authors: Hervochon Charles , Hennart Benjamin , Leroy Anne-Gaëlle , Corvec Stéphane , Boutoille David , Senneville Éric , Sotto Albert , Illes Gabriella , Chavanet Pascal , Dubée Vincent , Bleibtreu Alexandre , De Carné Marie-Charlotte , Talarmin Jean-Philippe , Revest Matthieu , Castan Bernard , Bellouard Ronan , Dailly Éric , Allorge Delphine , Dinh Aurélien , Le Turnier Paul , Gregoire Matthieu ,   the Dalbavancin Pharmacokinetics (DALBAP) study group, Le Turnier Paul , Boutoille David , Gaborit Benjamin Jean , Deschanvres Colin , Lecomte Raphael , Chauveau Marie , Leroy Anne-Gaëlle , Corvec Stéphane , Lavigne-Quilichini Vincent , Bémer Pascale , Guillouzouic Aurélie , Huon Jean-François , Navas Dominique , Gregoire Matthieu , Bellouard Ronan , Hervochon Charles , Dailly Eric , Waast Denis , Nich Christophe , Touchais Sophie , Crenn Vincent , Dubée Vincent , Berteau Florian , Chavanet Pascal , Goirand Françoise , Dinh Aurélien , Hennart Benjamin , Hoskovec Catherine , Mondon Damien , Illes Gabriela , Sotto Albert , Lechiche Catherine , Boclé Hélène , Lavigne Jean-Philippe , Castan Bernard , Bleibtreu Alexandre , Talarmin Jean-Philippe , Khatchatourian Lydie , Fangous Marie-Sarah , Gall Florence Le , Revest Matthieu , Cattoir Vincent , Lemaitre Florian , Senneville Eric , De Carné Marie-Charlotte , Therby Audrey , Balavoine Stéphanie , Bargain Pauline , Amara Marlène , Palette Catherine , Boisrenoult Philippe 
Published: October 2023

Abstract

Objectives
Limited pharmacokinetics data support dalbavancin long-term use in off-label indications and the optimal dosing regimen is debated. We aimed to describe dalbavancin concentrations in an observational retrospective multicentre study.

Methods
Patients from 13 French hospitals, treated with 1500 mg doses of dalbavancin and for whom therapeutic drug monitoring was performed from June 2018 to March 2021 were included. Dalbavancin plasma concentrations were described at peak and 1, 2, 3, 4, 6 and 8 weeks after the last 1500 mg dose. Concentrations in patients weighing more or less than 75 kg and with a GFR greater or less than 60 mL/min were compared. Microbiological data were collected and dalbavancin MIC was measured when possible.

Results
One hundred and thirty-three patients were included (69% treated for bone and joint infections, 16% for endocarditis). Thirty-five patients received a single dose of dalbavancin and 98 received several administrations. Two, 3 and 4 weeks after the last dose, median plasma concentrations were respectively 25.00, 14.80 and 9.24 mg/L for the first doses and 34.55, 22.60 and 19.20 mg/L for the second or subsequent doses. Weight and renal function had an impact on pharmacokinetics. Infection was documented in 105 patients (Staphylococcus spp. in 68% of cases). Staphylococcus aureus was isolated in 32.5% of cases (median MIC: 0.047 mg/L) and Staphylococcus epidermidis in 27% of cases (median MIC of 0.047 mg/L).

Conclusions
Plasma concentrations of dalbavancin were consistent with those described in clinical trials and those sought during the industrial development of the molecule.
Mental health outcomes in a population-based cohort of patients with prostate cancer
Authors: Hu Siqi , Chang Chun-Pin , Snyder John , Deshmukh Vikrant , Newman Michael , Date Ankita , Galvao Carlos , Haaland Benjamin , Porucznik Christina A , Gren Lisa H , Sanchez Alejandro , Lloyd Shane , O’Neil Brock , Hashibe Mia 
Published: October 2023

Abstract

Background
Few studies have evaluated mental health disorders comprehensively among patients with prostate cancer on long-term follow-up. The primary aim of our study was to assess the incidence of mental health disorders among patients with prostate cancer compared with a general population cohort. A secondary aim was to investigate potential risk factors for mental health disorders among patients with prostate cancer.

Methods
Cohorts of 18 134 patients with prostate adenocarcinomas diagnosed between 2004 and 2017 and 73470 men without cancer matched on age, birth state, and follow-up time were identified. Mental health diagnoses were identified from electronic health records and statewide health-care facilities data. Cox proportional hazard models were used to estimate hazard ratios. All statistical tests were 2-sided.

Results
The hazard ratios for mood disorders, including depression, among prostate cancer survivors increased for all follow-up periods compared with the general population. The hazard ratios for any mental illness increased with Hispanic, Black, or multiple races; people who were underweight or obese; those with advanced prostate cancer; and those undergoing their first course cancer treatment. We also observed statistically significantly increased hazard ratios for mental health disorders among patients with lower socioeconomic status (P &lt; .0001) and increasing duration of androgen-deprivation therapy (P = .0348). Prostate cancer survivors had a 61% increased hazard ratio for death with a depression diagnosis.

Conclusion
Prostate cancer diagnosis was associated with a higher risk of mental health disorders compared with the general population, which was observed as long as 10-16 years after cancer diagnosis. Providing long-term mental health support may be beneficial to increasing life expectancy for patients with prostate cancer.
rrlfe: software for generating and applying metallicity calibrations for RR Lyrae variable stars across a wide range of phases and temperatures
Authors: Spalding Eckhart , Wilhelm Ronald , De Lee Nathan , Long Stacy , Beers Timothy C , Placco Vinicius M , Kielkopf John , Lee Young Sun , Pepper Joshua , Carrell Kenneth 
Published: October 2023

ABSTRACT
RR Lyrae stars play a central role in tracing phase-space structures within the Milky Way because they are easy to identify, are relatively luminous, and are found in large numbers in the Galactic bulge, disc, and halo. In this work, we present a new set of spectroscopic metallicity calibrations that use the equivalent widths of the Ca ii K and Balmer H γ and H δ lines to calculate metallicity values from low-resolution spectra. This builds on an earlier calibration from Layden by extending the range of equivalent widths which map between Ca ii K and the Balmer lines. We have developed the software rrlfe to apply this calibration to spectra in a consistent, reproducible, and extensible manner. This software is open-source and available to the community. The calibration can be updated with additional data sets in the future.
UniTmp: unified resources for transmembrane proteins
Authors: Dobson László , Gerdán Csongor , Tusnády Simon , Szekeres Levente , Kuffa Katalin , Langó Tamás , Zeke András , Tusnády Gábor E 
Published: October 2023

Abstract
The UNIfied database of TransMembrane Proteins (UniTmp) is a comprehensive and freely accessible resource of transmembrane protein structural information at different levels, from localization of protein segments, through the topology of the protein to the membrane-embedded 3D structure. We not only annotated tens of thousands of new structures and experiments, but we also developed a new system that can serve these resources in parallel. UniTmp is a unified platform that merges TOPDB (Topology Data Bank of Transmembrane Proteins), TOPDOM (database of conservatively located domains and motifs in proteins), PDBTM (Protein Data Bank of Transmembrane Proteins) and HTP (Human Transmembrane Proteome) databases and provides interoperability between the incorporated resources and an easy way to keep them regularly updated. The current update contains 9235 membrane-embedded structures, 9088 sequences with 536 035 topology-annotated segments and 8692 conservatively localized protein domains or motifs as well as 5466 annotated human transmembrane proteins. The UniTmp database can be accessed at https://www.unitmp.org.
Genome-wide direct quantification of in vivo mutagenesis using high-accuracy paired-end and complementary consensus sequencing
Authors: You Xinyue , Cao Yiyi , Suzuki Takayoshi , Shao Jie , Zhu Benzhan , Masumura Kenichi , Xi Jing , Liu Weiying , Zhang Xinyu , Luan Yang 
Published: October 2023

Abstract
Error-corrected next-generation sequencing (ecNGS) is an emerging technology for accurately measuring somatic mutations. Here, we report paired-end and complementary consensus sequencing (PECC-Seq), a high-accuracy ecNGS approach for genome-wide somatic mutation detection. We characterize a novel 2-aminoimidazolone lesion besides 7,8-dihydro-8-oxoguanine and the resulting end-repair artifacts originating from NGS library preparation that obscure the sequencing accuracy of NGS. We modify library preparation protocol for the enzymatic removal of end-repair artifacts and improve the accuracy of our previously developed duplex consensus sequencing method. Optimized PECC-Seq shows an error rate of &lt;5 × 10−8 with consensus bases compressed from approximately 25 Gb of raw sequencing data, enabling the accurate detection of low-abundance somatic mutations. We apply PECC-Seq to the quantification of in vivo mutagenesis. Compared with the classic gpt gene mutation assay using gpt delta transgenic mice, PECC-Seq exhibits high sensitivity in quantitatively measuring dose-dependent mutagenesis induced by Aristolochic acid I (AAI). Moreover, PECC-Seq specifically characterizes the distinct genome-wide mutational signatures of AAI, Benzo[a]pyrene, N-Nitroso-N-ethylurea and N-nitrosodiethylamine and reveals the mutational signature of Quinoline in common mouse models. Overall, our findings demonstrate that high-accuracy PECC-Seq is a promising tool for genome-wide somatic mutagenesis quantification and for in vivo mutagenicity testing.
Jiangnan Sizhu in the Greater Suzhou Area
Authors: Dujunco Mercedes M. 
Published: October 2023

Abstract
This essay looks at Jiangnan sizhu (江南絲竹) as it is performed in a village in the greater Suzhou area and in the county-level city of Taicang, both in Jiangsu province. In the process, it is shown how this regional sizhu tradition has a much broader repertoire than the badaqu (八大曲, “eight great pieces”) routinely performed in Jiangnan sizhu music clubs in Shanghai, some of which has been reintroduced as part of efforts at revitalization and sustainability. Furthermore, it discusses how annexing Jiangnan sizhu with two of its sibling genres—the music of regional operas such as kunqu (崑曲) and huju (滬劇) as well as shifan luogu (十番鑼鼓) music—has contributed to its flourishing and continued practice in these two places.
“Minorities” and the Mainstream
Authors: Wong Chuen-Fung 
Published: October 2023

Abstract
This chapter concerns non-Han indigenous music as it has become minoritized in a shared yet divergent process of cultural enlightenment with the Han over the past few decades in China. Examples are drawn primarily from the music of the Uyghur to examine the assimilationist practices and cultural appropriation in Chinese music today. As Chinese composers and musicians continue to claim inspirations in their encounter with the land and the peoples in far-flung, non-Han territories, questions that problematize concepts of hybridity and otherness also become particularly relevant. The minority/majority binary that has loomed so large in Chinese music scholarship and performance today, this chapter suggests, is fundamentally a modern construct, manifested through an uneasy yet symbiotic musical relationship between the “minorities” and the mainstream Han Chinese. The shifting senses of belonging is also contingent upon such a relationship as musicians and audiences envision their own musical futures.
The Huxuan and Huteng Dances
Authors: Weiping Zhao 
Published: October 2023

Abstract
With the opening of the Silk Road in the Han dynasty (581–618 CE), foreign cultures gradually came to occupy an important position in China. Musicians from overseas brought rich cultures to China. From the Southern and Northern dynasties (420–589 CE) to the Tang dynasty, foreign musicians, musical instruments, and musical dances entered China through the Gansu corridor from Central Asia, West Asia, and South Asia and quickly entered the city of Chang’an, profoundly affecting Han culture. The popular huxuan and huteng dances were welcomed by local people who scrambled to imitate them. This chapter discusses how these dances entered China and influenced Chinese people and how China accepted, accommodated, and gradually localized these foreign musical genres. This precipitates a discussion of various phenomena associated with cultural coalescence.
Time, Politics, and Political Science
Authors: Goetz Klaus H. 
Published: October 2023

Abstract
The language of politics—whether domestic or international—is saturated with time-related references. So is the language of political science, whether it relates to substantive concerns, concepts, theories, or methods. The emphasis on time in politics and political science has become more pronounced, as much of contemporary political debate and analysis has come to be framed in terms of crisis, turbulence, and emergency. The brief survey of the contributions to this Handbook shows the extent to which time-centered research in political science has advanced across the subdisciplines of comparative politics and government; comparative public policy; international relations; and political theory. Seven observational foci guide much of this scholarship: time embedded in institutions, processes, organizations, actor constellations, ideas, policy problems, and public policies. The time-centered conceptual agenda that emerges can be summarized by four terms: explication, specification, systematization, and application. If research on time and politics is to flourish, commonly agreed-upon concepts that are applied consistently are required so that empirical knowledge can be accumulated and, where necessary, revised.
Canadian Musicals and the Commercial Theatre of Broadway and the West End
Authors: Atkey Mel 
Published: October 2023

Abstract
For decades Canadian musical theatre writers hoped to conquer New York and/or London, without much luck. These attempts have included such ‘flops’ as Rockabye Hamlet, Billy Bishop Goes to War, and The Story of My Life. The essay discusses the general history of musicals originating in Canada and how they were exported. It also explores why after many years of trying, two shows—The Drowsy Chaperone and Come from Away—succeeded on Broadway within a relatively short period of time.
Musicals in Mexico
Authors: Méndez Emilio 
Published: October 2023

Abstract
This chapter explores how producers have attempted since 1956 to attract theatre-goers in Mexico City with local productions of translated Anglophone musicals and how such attempts have prompted the Mexican theatre industry to build up its own catalogue of original musicals. It discusses how local audiences and critics have had to reconcile their experiences of the traditional Mexican revista (revue) with the modern Broadway and West End musical. Alongside the precipitate production of Ni fu ni fa (1955), this essay considers the cases of Rentas congeladas (1960) and Las fascinadoras (1961)—early works that endeavoured to bridge the gap between revista and musical—as well as Papacito piernas largas (1977), ¡Qué plantón! (1989), and Mentiras (2009), long-running and successful Mexican shows. Examining overlapping cultural-aesthetic and economic considerations as well as critical responses, the chapter proposes four major stages of the assimilation process of Anglophone musical theatre as a foreign form and the development of indigenous Mexican musicals.
That Special Relationship
Authors: Gordon Robert 
Published: October 2023

Abstract
The essay traces the development of a ‘special relationship’ between Britain and the United States between 1945 and 1982 in cultural terms by examining the career and reception of the three female American musical theatre stars who achieved the highest profile in the United Kingdom—Dolores Gray, Mary Martin, and Elaine Stritch. Their performances were imbricated within changing postwar understandings of femininity, typifying for British audiences the modernity that the United States had come to represent. Their comparatively liberated assertion of ‘naturalness’ in speech and behaviour replaced the class-bound formality of British performances of gender and sexuality with the less repressed images of American identity. The particular affection with which these three stage stars were embraced manifested changes in British attitudes to themselves and to the popular culture of the United States.
Between Starlight Express and My Fair Lady, Frank Wildhorn and Martin Lingnau
Authors: Döhl Frédéric 
Published: October 2023

Abstract
This essay investigates the repertoire of imported Anglo-American musicals after the reunification of East and West Germany (1989–1990) as the core of contemporary popular musical theatre in German-speaking countries (Germany, Austria, and northern Switzerland), the third-biggest market for Anglophone popular musical theatre in the world in terms of gross income, audience attendance, productions, and repertoire diversity. Particular attention is paid to living composers and imported Anglo-American works that premiered after the mid-1990s, including comparative case studies of Stephen Sondheim and Frank Wildhorn. Additionally, the paper focuses on the domestic production of new musicals, especially those by Martin Lingnau.