bluuebunny/crossref_metadata_2025_split huggingface dataset:
New technologies in vascular rehabilitation
Authors: Prosperi Loris , Barassi Giovanni , Supplizi Marco , Giancola Alessandra , Di Matteo Celeste , Manca Mara , Gallo Laura , Di Iorio Angelo 
Published: October 2023

Lymphedema of lower limbs represents an important health problem, characterized by the necessity to identify new methods of treatment. The aim of this study was to evaluate the efficacy of the treatment with Lymphatic Kinesiology Taping (LKT) or Intermittent Pneumatic Compression therapy (IPC) on a homogeneous group of 40 women affected by primary lymphedema within stage 2 of lower limbs, comparing the two methods. Patients were equally and randomly divided into a group A subjected to application of LKT and group B subjected to IPC. All patients were evaluated through electric bioimpedentiometry (analysis of Total Body Water and Extracellular Water) and circumferential measurement of lower limbs through a measurement tape, both before and after the protocol (T0 and T1). Both treatment groups highlighted an improvement of the lymphedema, with a marked reduction of volume of lower limbs and a better hydric balance of the body. LKT and IPC can be considered as viable options for the treatment of primary lymphedema within stage 2 of lower limbs.
Immigrant workers in the construction sector in italy: impact on safety and health
Authors: Misale Fiorenza 
Published: October 2023

The profound changes that have taken place in Italian society have led to very strong changes in the labor market which is segmented, heterogeneous, outsourced and characterized by the growth of medium and medium-small businesses where the implementation of current legislation on safety in the workplace is often neglected and occupational risks are underestimated. The disadvantage in which immigrant workers find themselves is greater than Italian workers for various reasons, as well as for social issues also due to problems of linguistic understanding. Understanding security measures is also a purely linguistic fact and this is certainly a crucial aspect especially in the early stages of job placement and in job changes, the perceived difficulties at the level of linguistic communication are particularly felt by immigrant workers, not by chance. the request for information in the original language appears widespread. It would be advisable to build training courses tailored to the needs of immigrants, compulsory language preparation courses, specific courses connected in particular to the risk sectors in which they find themselves and aimed at making their culture of safety at work dialogue with the Italian one.
Nuclear medicine in the pediatric field
Authors: Barone Sebastiano , Pagliuso Serena , Pagliuso Luana 
Published: October 2023

The work presented describes the main ways of preparing radiopharmaceuticals and carrying out nuclear-medical examinations in pediatric patients. Through the differences in the execution of the tests, the importance of dosimetry is revealed, i.e. the diagnostic reference levels, in which the percentage of activity that must be administered to the child on the basis of that introduced in the adult is indicated. Through a study performed on pediatric patients, subjected to nuclear-medical investigations, the validity of the LDRs is reported according to the scheme in tab. 6 (EANM-EUROPEAN ASSOCIATION OF NUCLEAR MEDICINE). Through a study conducted in pediatric patients, subjected to medical - nuclear investigations, the importance of the dose is noted in order to obtain greater benefits in the patient and high quality images for diagnostic purposes. By carrying out pediatric-radiopharmaceutical calculations, it is possible to reproduce the aforementioned, ie an optimization of the dose.
Using body surface area:
Child’s body surface area (m2) _______________________________________ = 0.53g: 1.8 g = 29% - 2.9 mCi Adult’s body surface area (m2)
Using organ weight:
Target organ weight of child (g) _______________________________________ = 93 g: 310g = 30% - 3.0 mCi Target organ weight of adult (g) .

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Remote mental health rehabilitation: Social Health Educators between experience and innovation
Authors: Cimino Maurizio , Semisa Domenico 
Published: October 2023

Following the Covid-19 pandemic, in our country strict containment measures have been put in place to safeguard, first and foremost, vulnerable swathes of the population, including people affected by psychiatric disorders. Nevertheless, a large part of Mental Health Centers activities, territorial rehabilitation, counselling sessions, aid and psychoeducational activities, social skills training, workshops, as well as family support, monitoring and network activities with rehabilitation centers workers and users have been rearranged in another modality, namely the socalled “remote modality”. Despite the undisputed and essential value of human contact and face-to- face relationships, the work reported here shows the importance, for Mental Health Services, of employing communicative modalities, like the current alternative virtual ones which, after the initial difficulties were overcome, have been appreciated, further implemented and widely used by now because of their efficacy, so much so that it is thought that they could eventually be combined with traditional modalities.
РОЗПОДІЛ ВИТРАТ МАЙБУТНІХ ПЕРІОДІВ ЗА ОБЕРНЕНИМ МЕТОДОМ НА ОСНОВІ ПОДАТКУ НА ДОДАНУ ВАРТІСТЬ
Authors: Сук Петро 
Published: October 2023

Податок на додану вартість – це непрямий податок, що включається в ціну реалізації продукції (товарів, робіт, послуг), та сплачується продавцю при її купівлі покупцем, а до бюджету перераховується продавцем.Податок на додану вартість становить частину доходу від реалізації продукції (товарів, робіт, послуг), а тому може бути базою для розподілу витрат майбутніх періодів.Доведено доцільність використання методу розподілу витрат майбутніх періодів на основі податку на додану вартість.На прикладі здійснено розрахунок розподілу витрат майбутніх періодів за допомогою методу на основі податку на додану вартість. Запропоновано два способи визначення методу розподілу витрат майбутніх періодів на основі податку на додану вартість: 1) від початкової суми; 2) від залишкової суми.
PECULIARITIES OF TACTICAL ACTIONS OF ASSAULT UNITS OF THE ARMED FORCES OF UKRAINE IN THE WAR AGAINST THE RUSSIAN FEDERATION
Authors: Tokar Vladislav , Sievidov Oleh , Mardarenko Olena 
Published: October 2023

The armed confrontation with the Russian Federation started back in 2014, and gained its full force during the full-scale invasion in 2022. And since then, the approach to warfare has changed significantly, because war is just one of the forms of evolution. So, if there is no eternal learning from our mistakes or using the experience of our predecessors, all conflicts would last forever. as an example, let’s take one period of history, the period of the beginning of the Gulf wars, the period when the United States was involved in the conflict between Iraq and Kuwait. Exactly at that time the system of satellites was first used and it allowed to target and correct, and brought many other innovative decisions in the wars US Army against Iraq. This period showed the world that military progress does not stand still. As to our current topic, we will consider how the tactical actions of Ukrainian units have changed since the beginning of the full-scale invasion.
РОЗРОБКА АВТОМАТИЗОВАНОІ СИСТЕМИ КОНТРОЛЮ І УПРАВЛІННЯ ДОСТУПОМ У СЕРВЕРНІ ПРИМІЩЕННЯ
Authors: Дубук Василь , Васік Святослав 
Published: October 2023

У статті представлено результати розробки автоматизованої системи контролю і управління доступом у серверні приміщення, що реалізує різні методи контролю і управління доступом та забезпечує можливості регулювання рівня безпеки. Розроблено, представлено та описано роботу структурної схеми автоматизованої системи контролю та управління доступом до серверного приміщення. Визначено апаратні та програмні засоби для реалізації проекту автоматизованої системи контролю і управління доступом до серверних приміщень. Удосконалено метод контролю і управління доступом до серверних приміщень на основі сучасних інформаційних технологій. Наведено висновки.
ІНТЕРАКЦІЯ ЯК КОМУНІКАТИВНА ВЗАЄМОДІЯ У МИСТЕЦТВІ
Authors: Білан Тетяна 
Published: October 2023

В статті проаналізовано комунікативну взаємодію мистецтва, визначено універсальні умови можливого взаєморозуміння, проаналізовано зміст цінностей у взаємозв’язку з соціальним світом людини, обґрунтовано підходи до розуміння творчої діяльності людини; визначено доцільність застоcування головних ідей комунікативної теорії не лише в аналізі сфери практичного розуму, а й у дослідженні інших вимірів людського буття, зокрема мистецтві, і констатовано, що це дає можливість дискутувати про інтертекстуальні рефлексії мистецтва.
IMPLEMENTATION OF EUROPEAN REGULATORY EXPERIENCE AND MANAGEMENT OF THE PHARMACEUTICAL SECTOR OF THE HEALTH CARE INDUSTRY IN UNIVERSITY EDUCATION
Authors: Voskoboinikova H. , Dovzhuk V. , Dovzhuk N. , Konovalova L. 
Published: October 2023

The article is devoted to the implementation the experience of the pharmaceutical sector of the EU countries. The strategy of reforms of the pharmaceutical sector of the EU countries are being analyzed. Authors give their view to solving the problems, among them is the the development of a strategy to ensure the quality of training of masters of pharmacy in university education.
ПАРАДИГМА ІННОВАЦІЙНИХ ЗМІН В АГРАРНО-ПРОМИСЛОВОМУ СЕКТОРІ УКРАЇНИ У 90-Х РОКАХ ХХ СТОЛІТТЯ
Authors: Каденюк Олександр 
Published: October 2023

В статті досліджуються основні шляхи реформування аграрного виробництва яке об’єднане в єдину систему – агропромисловий комплекс. Це багатогранна галузь народного господарства. Він має у своєму складі чотири взаємопов`язані блоки. До першого входять галузі сільськогосподарського машинобудування, енергетики, виробництва будівельних матеріалів, мінеральних добрив. Другий блок становить аграрний сектор. Третій блок - це сфера заготівель сільськогосподарської продукції, переробні галузі по виробництву сільськогосподарської продукції, торгівельні організації. До четвертого блоку входять владні структури, науково-дослідні установи та учбові заклади, які беруть участь у інформаційному та кадровому забезпеченні агропромислового виробництва. Діяльність цих блоків відбувається в умовах зміни економічних відносин, форм власності та господарювання. Це вимагає оволодіння відповідними методами управління, які виходять з принципів ринкової економіки.
The Influence of Total Quality Management (TQM) and Characteristics of Management Accountig Information Systems on Managerial Performance
Authors: Januarty Tamy Ali , Sundari Siti Asyiah 
Published: October 2023

Managerial performance is one of the things that can drive the success of a company's goals. There are several things that can affect and improve managerial performance including total quality management and management accounting information systems. The application of total quality management will help the managerial role to further improve its performance so that it can be carried out properly. In addition, the existence of an available management accounting information system will support the control and decision-making process of a manager. This study aims to determine the effect of total quality management and the characteristics of management accounting information systems on managerial performance at PT. So Good Food Jakarta Branch. Application of total quality management and management accounting information systems at PT. The So Good Food Jakarta Branch has been running and is well available, but there needs to be improvement so that the implementation of total quality management and management accounting information systems can run optimally. The method in this study was to conduct a questionnaire survey with an ordinal scale form to 40 respondents from PT. So Good Food Jakarta Branch, then data processing is carried out using SEM-PLS data analysis techniques and is designed with a quantitative approach to descriptive analysis and verification. The results of this study are expected to be a solution to problems related to managerial performance at PT. So Good Food Jakarta Branch.
The results of this study prove that: (1) total quality management has an effect on managerial performance, (2) the characteristics of management accounting information systems have an effect on managerial performance
Changes in immunity during the second trimester of pregnancy in women with exacerbation of bronchial asthma associated with reactivation of cytomegalovirus infection
Authors: Odireev A. N. , Gorikov I. N. , Nakhamchen L. G. , Andrievskaya I. A. , Ishutina N. A. , Prokopenko A. V. 
Published: October 2023

Aim. To evaluate changes in immunity in the second trimester of pregnancy in women with exacerbation of bronchial asthma associated with reactivation of cytomegalovirus infection (CMVI).Materials and methods. The concentration of secretory immunoglobulin A (sIgA), immunoglobulin A (IgA), immunoglobulin G (IgG), immunoglobulin M (IgM) and circulating immune complexes (CIC) was studied in 112 women at 21-24 weeks of uncomplicated pregnancy and pregnancy complicated by exacerbation of mild-to-moderate asthma associated with CMVI. The first group included 30 women seronegative for CMV, with an uncomplicated pregnancy. The second group consisted of 30 patients with exacerbation of mild asthma, initiated by the acute phase of CMVI, which induces the development of chronic compensated placental insufficiency. The third group consisted of 27 patients with moderate asthma in the acute stage against the background of the acute phase of CMVI, leading to the formation of chronic compensated placental insufficiency. The fourth group included 25 patients with exacerbation of moderate asthma with CMV etiology, initiating the development of chronic subcompensated placental insufficiency.Results. In women of the second group, the concentration of sIgA was 5.91±0.371 mg/L, IgA – 2.64±0.089 mg/mL, IgG – 15.4±0.791 mg/mL, IgM – 2.32±0.144 mg/mL, CIC – 0.176±0.004 optical density units (in the first group, respectively, 4.31±0.266 mg/L, p<0.001; 2.37±0.06 mg/mL, p<0.05; 13.3±0.293 mg/mL, p<0,05; 1.11±0.06 mg/mL, p<0.001; 0.092±0.005 optical density units, p<0.001). In patients of the third group, in contrast to the second one, no differences in immunity parameters were detected. In the fourth group, in comparison with the third one, lower parameters of sIgA (3.21±0.213 mg/L, p<0.001), IgA (1.43±0.081 mg/mL, p<0.001), as well as higher IgG values were detected (19.8±0.418 mg/mL, p<0.001), IgM (2.94±0.082 mg/mL, p<0.01) and CIC (0.198±0.005 optical density units, p<0.05).Conclusion. In patients with moderate asthma with exacerbation against the background of CMVI reactivation, which initiates the formation of chronic subcompensated placental insufficiency, in contrast to women with moderate asthma in the stage of CMVI exacerbation in the second trimester of pregnancy, leading to chronic compensated placental insufficiency in the third trimester of gestation, a more pronounced imbalance of humoral immunity and autoimmune disorders are found, which are important in the development of chronic placental dysfunction.
Dose-dependent effect of ethanolamine of eicosapentaenoic acid on the synthesis of oxylipins by blood cells of patients with bronchial asthma <i>in vitro</i>
Authors: Kovalenko I. S. , Bocharova N. V. , Novgorodtseva T. P. , Denisenko Yu. K. 
Published: October 2023

Introduction. The search for new highly effective methods for the treatment and control of bronchial asthma is an urgent task in pathophysiology and pharmacology. A promising substance for the regulation of systemic chronic inflammation is N-acylethanolamine (EPEA) of eicosapentaenoic acid, which exhibits immunoregulatory properties.Aim. To study the dose-dependent effect of eicosapentaenoic acid ethanolamine on the synthesis and metabolism of oxylipins by blood cells in patients with asthma under in vitro conditions.Materials and methods. The object of the study was the whole blood of 5 patients with controlled mild-to-moderate asthma and 6 healthy people. The in vitro experiment was carried out in lipopolysaccharide-stimulated blood after incubation for 30 minutes. Then the experimental substance N-acyl-ethanolamine of eicosapentaenoic acid (NAE 20:5) was added at concentrations of 1.0, 5.0 and 10.0 µM and incubated at 37ºC for 6 hours in gentle mixing mode. The level of oxylipins was studied by enzyme immunoassay.Results. Experimental exposure to N-acylethanolamines of eicosapentenoic acid had the following effects. Under the influence of ethanolamine of eicosapentaenoic acid at a concentration of 1 µM, the level of PGE2 decreased by 51% (p<0.001) and the amount of 15-HEPE increased by 32% (p<0.05) in lipopolysaccharide-induced blood plasma relative to the values before exposure to ethanolamine. Also EPEA at this dosage showed a tendency to increase the level of 18HEPE. Exposure to EPEA at 5µM resulted in a significant decrease in LTB4 levels by 34% (p<0.001), PGE2 levels by 51% (p<0.001), as well as an increase in 12-HEPE levels by 33% (p<0.01), 15-HEPE by 36% (p<0.05) and 18-HEPE by 87% (p<0.01). Under the influence of EPEA at a dosage of 10 µM, a statistically significant effect on the entire spectrum of the studied oxylipins was revealed. Thus, the use of this dose of ethanolamide in LPS-induced blood showed a decrease in the concentration of LTB4 by 37% (p<0.001), LXA4 by 22% (p<0.05), PGE2 by 50% (p<0.001) and an increase in 5HEPE concentration by 25% (p<0.05), 12-HEPE by 76% (p<0.001), 15-HEPE by 75% (p<0.001), 18-HEPE by 155% (p<0.001) relative to pre-EPEA values.Conclusion. Further study of NAE fatty acids opens up new perspectives in the study of targeted methods for correcting the inflammatory response in bronchial asthma.
The effect of <i>TRPV1</i> gene polymorphism on the development of progressive course of chronic obstructive pulmonary disease
Authors: Gassan D. A. , Naumov D. E. , Kotova O. O. , Sugaylo I. Yu. , Sheludko E. G. , Afanas’eva E. Yu. , Gorchakova Y. G. 
Published: October 2023

Introduction. It is known that the course of chronic obstructive pulmonary disease (COPD) may vary depending on the rate of bronchial obstruction progression. It has been shown that TRPV1 channels play an important role in the formation of some pathological syndromes typical for COPD.Aim. To study the effect of single nucleotide polymorphisms (SNPs) of TRPV1 gene on the rate of bronchial obstruction progression in COPD patients.Materials and methods. We examined 103 patients with COPD, including 47 with rapid progression of bronchial obstruction (decrease in FEV1≥50 ml/year). SNPs rs460716, rs222749, rs222747, and rs8065080 were genotyped by LATE-PCR.Results. We established that rs460716 SNP had a significant effect on the development of progressive bronchial obstruction in COPD. The CC+TT genotypes were more common among patients with progressive disease (48.9% versus 23.2%), while the heterozygous genotype was protective (p=0.006). Differences remained significant after adjusting for sex, age, pack-year index and baseline FEV1 (OR 3.2; 95%CI [1.32; 7.57], p=0.009).Conclusion. The obtained results indicate a negative influence of the homozygous genotypes carriage for TRPV1 rs460716 SNP on the course of COPD.
Isolation of a rare pathogen <i>Chryseobacterium indologenes</i> in patients with pneumonia
Authors: Golubeva A. O. , Bondarenko A. P. , Natykan Yu. A. , Trotsenko O. E. , Kurganova O. P. , Pshenichnaya N. Yu. , Taran E. K. 
Published: October 2023

Introduction.Chryseobacterium indologenesbacteria are rarely detected, poorly studied opportunistic bacteria of the nonfermenting gram-negative bacilli group that are characterized by high intrinsic and acquired multidrug resistance and involvement in healthcare associated infections.Aim.To analyze detection rate ofC. indologenesstrains from various biomaterials obtained from patients with pneumonia, as well as levels of pathogen drug resistance to antimicrobial drugs.Materials and methods.The research included 1740 clinical samples obtained from patients with pneumonia hospitalized in in-patient facilities of the Khabarovsk city during the COVID-19 pandemic. Clinical samples included 1305 respiratory samples (744 sputum samples and 561 nasopharyngeal swabs), 435 samples of autopsy material (lung tissue) obtained from patients with a fatal outcome of the disease. The study was performed via classical bacteriological method. Pathogens were identified with Vitek 2 bacteriological analyzer and Vitek MS mass spectrometer. Sensitivity to antimicrobial drugs was determined by disk-diffusion method and in a bacteriological analyzer.Results.A comparative analysis of detection of the entire nonfermenting gram-negative bacteria (NFGNB) group andC. indologenesfrom various clinical samples was carried out. Detection rate of NFGNB equaled 17.3%. NFGNB were isolated from autopsy material most often ‒ in 31.7% of cases, less often ‒ from sputum and nasopharyngeal smears (13.8% and 10.7%, respectively).C. indologeneswas detected in 0.5% of the cases (8 isolates out of 1740 samples). Isolation of this pathogen was most frequent in nasopharyngeal smears – in 1.1% (6 cases out of 561 samples), least frequent ‒ from sputum, which totaled 0.3% (2 isolates from 744 samples). The detection rate of the pathogen in respiratory samples equaled 0.6% (8 isolates out of 1305 samples). This pathogen was not found in the autopsy material. Carbapenem-resistant variants ofC. indologeneswere isolated in 75% (6 cases out of 8) of the cases.Conclusion.Further intensifying of diagnostic methods will result in more frequent detection of these unusual pathogens, clinical significance of which needs more justification.
Assessment of Stakeholder Involvement and Borehole Water Projects Delivery in Kogi West Senatorial District, Nigeria
Authors: Adepoju Adeyemi , Obademi Tokunboh 
Published: October 2023

There is huge challenges in the supply of clean water for household consumption in many countries, in particular, Nigeria. Kogi West Senatorial District (KWSD) has witnessed more borehole projects in Nigeria but the challenge of clean water still persists. This has necessitated more research into the field of water resources to combat such challenges in line with the sustainable development goals (SDGs). This study assessed the effects of stakeholders’ involvement in KWSD, Nigeria, with a view to improving the delivery of borehole water projects in the study area. Data were collected through a structured questionnaire from 267 stakeholders comprising Lower Niger River Basin Development Authority (LNRBDA) staff, community leaders and community members that were selected using simple random sampling technique. The study objective was assessed with inferential statistics (Partial Least Square in Structural Equation Modelling). The results disclose the direct path coefficients for Initiation stage (bIS), Planning stage (bPS), Execution stage (“bES”), Monitoring and closure stage (bMS), Post construction stage (bPCS), Budget (cBG), Time Delivery (cTD) and Stakeholder’s Satisfaction (cSS). The results illustrated positives and significant relationship with bES -> cBG (β = 0.422, t = 5.708), bES -> cSS (β = 0.495, t = 6.366), bES -> cTD (β = 0.493, t = 7.422), bMS -> cBG (β = 0.164, t = 2.643), bPCS -> cTD (β = 0.257, t = 5.7084.440), and negative significant relationship with bMS -> cTD (β = -0.184, t = 2.547) and bPS -> cSS (β = - 0.182, t = 2.586). The study concludes that stakeholders’ involvement is a strong predictor of viable Borehole water projects delivery in the study area.