bluuebunny/crossref_metadata_2025_split huggingface dataset:
A sulfonated and nitrated polyether ether ketone/polyvinyl chloride modified atmosphere packaging delays the deterioration of grapes
Authors: Tang Xianhui , Huang Yuting , Zhu Liang 
Published: January 2025

AbstractBACKGROUNDPolyether ether ketone (PEEK) was modified by a sulfuric and nitric acid mixed system to improve the solubility of the material and the gas selective permeability of the film. SN1 and SN5, synthesized from mixed acid systems (with ratios of nitric acid and sulfuric acid of 1:1 and 1:5, respectively) were chosen because they had comparable nitro groups but differing sulfonyl groups. To investigate the impact of the type and content of sulfonated and nitrated polyether ether ketone (SNPEEK) on the structure and physicochemical properties of the films, SN1/polyvinyl chloride (PVC) and SN5/polyvinyl chloride films were made by adding varying amounts of SN1 and SN5 (0.5%, 1.0%, 1.5%, 2.0% and 2.5 wt%), respectively.RESULTSSNPEEK (with ratios of nitric acid and sulfuric acid of 1:1–9) with high nitric acid group concentration outperformed nitrated polyether ether ketone (NPEEK) (with ratios of nitric acid and sulfuric acid of 3–9:1) with a low nitric acid concentration in terms of solubility at room temperature and expanded the application range. The inclusion of SNPEEK resulted in more micropores on the membrane microstructure, and higher contents of ‐SO3H and ‐NO2 groups enhanced the polarity, which improved permeability and selectivity for CO2 and O2 and the moisture permeability of the membranes. During grape storage (4 ± 1 °C), 1.0% SN1/PVC and 1.0% SN5/PVC membranes reached equilibrium gas concentration on day 4 (4.6–5.4% CO2, 17.6–18.1% O2; 3.5–4.1% CO2 and 18.6–19.1% O2), grapes showed lower electrolyte leakage as well as higher hardness, total soluble solid content and vitamin C content.CONCLUSIONBecause there are few studies on modified PEEK air conditioning packaging for grape preservation, SNPEEK/PVC membrane has practical value. In the present study, 1.0% SN1/PVC and 1.0% SN5/PVC membranes extended the shelf life by more than 16 and 8 days, respectively, compared to the blank group (unsealed packaging). © 2025 Society of Chemical Industry.
Banana rachis nanocellulose: a natural stabilizer for Pickering nanoemulsion and its potential as a carrier of β‐carotene in food systems
Authors: Basumatary Beatrice , Mahanta Charu Lata 
Published: January 2025

AbstractBACKGROUNDIncorporating β‐carotene into food systems improves nutritional value by providing a natural source of vitamin A. However, maintaining its stability during processing and storage is a significant barrier for its bioavailability.RESULTSThis study investigated the utilization of banana rachis nanocellulose (BRNC) as a natural stabilizer in the formulation of Pickering nanoemulsion (PNE). Parameters were optimized for developing PNE using BNRC. A 20 g kg −1 concentration of BNRC was found to be suitable in terms of particle size and zeta potential. The PNE, with a particle size of 196 nm and a polydispersity index (PDI) of 0.463, remained stable for 35 days. β‐Carotene (1 g kg−1) on encapsulation in PNE showed enhanced chemical stability with a retention rate of 0.81. The BRNC‐based PNE demonstrated enhanced stability against phase separation. Additionally, β‐carotene‐infused PNE mayonnaise was developed and characterized. Hydroperoxide formation in developed mayonnaise increased in control sample up to day 14, while samples with β‐carotene showed no significant increase (P > 0.05) throughout the analysis period. Furthermore, mayonnaise added with the BRNC‐based PNE enriched with β‐carotene exhibited improved functionality, including enhanced rheological (R2 = 0.99), textural, and colour attributes. High‐performance liquid chromatography (HPLC) analysis showed 612.6 ± 0.8 μg β‐carotene kg −1 of mayonnaise.CONCLUSIONThe developed mayonnaise successfully reduces fat content while enhancing its overall functionality. The potential of BRNC as a promising bio‐based stabilizer was thus elucidated for the development of functional food products with improved nutritional value and stability. © 2025 Society of Chemical Industry.
Theoretical Kinetic Study of NH2 Reactions With Dimethyl Ether and Diethyl Ether: Implications for Kinetic Modeling
Authors: Giri Binod Raj , Mai Tam V.‐T. , Shrestha Krishna Prasad , Giri Sushant , Naik R. Thirumaleswara , Verma Rakhi , Mauss Fabian , Huynh Lam K. 
Published: January 2025

ABSTRACTAmmonia (NH3) and hydrogen (H2) have emerged as promising carbon‐free fuels to help mitigate global warming by reducing greenhouse gas emissions. Our ongoing research currently focuses on understanding the combustion characteristics of NH3 blends with oxygenates and hydrocarbons, uncovering the critical role of carbon–nitrogen cross‐reactions in accurately modeling their combustion behavior. Amino (NH2) radicals, which are abundant in ammonia and nitrogen‐rich environments, strongly influence the low‐temperature reactivity of NH3‐hydrocarbon/oxygenate mixtures, affecting overall reactivity and emission characteristics. Recognizing the importance of NH2 radicals, we investigated the reaction kinetics of NH2 with dimethyl ether (DME, CH3OCH3) and diethyl ether (DEE, CH3CH2OCH2CH3) using appropriate high‐level ab initio and statistical rate theory methods. We computed the potential energy profiles at the CCSD(T)/cc‐pV(T, Q)Z//M06‐2X/aug‐cc‐pVTZ level of theory, analyzing the reactivity of NH2 radicals at various C─H sites of these diethers. Incorporating these newly derived rate parameters, our updated kinetic model successfully captures previous experimental data, addressing the modeling challenges encountered in our earlier studies. Our findings, including insights into the impact of NH2 radicals, contribute to an understanding of ammonia combustion and its potential in achieving carbon‐neutral energy systems.
Photoacoustics for Direct Light‐Guiding Inside Transparent and Scattering Media
Authors: Ricci Pietro , Colom Mateu , Mestre‐Torà Blanca , Duocastella Martí 
Published: January 2025

AbstractThe rapid and precise delivery of light at targeted positions on a sample is essential for any light‐based application, including laser materials processing or imaging. However, current systems for light control rely on bulky and costly optical components placed outside the sample. This configuration can be limited by the sample's geometry, poor flexibility in the illumination, and shallow penetration depth, particularly for scattering samples. Here a novel approach is proposed for guiding light within optically transparent and scattering media while obviating any external components. By simply employing an absorptive material and a pulsed laser, this method leverages the photoacoustic generation of a localized pressure wave to induce refractive index gradients within a medium. These gradients act as non‐invasive optical waveguides, that allow for light focusing and guiding across several millimeters at sub‐microsecond time scales. The principle and implementation of this method are described, the light‐guiding effects through various tissue phantoms are simulated and measured, and micrometric laser marking of a photo‐absorbing layer is demonstrated inside a 7‐mm‐thick scattering phantom. The possibility to operate with endogenous absorbing materials and low pressures makes photoacoustic‐enabled light guiding a promising step toward rapid light delivery at conditions not feasible today.
How Argument Numerosity Shapes Firm‐Generated Content Effectiveness
Authors: Pozharliev Rumen , De Angelis Matteo , Cascio Rizzo Giovanni Luca 
Published: January 2025

ABSTRACTDespite the growing popularity of firm‐generated content (FGC), defined as product‐oriented communication that an organization initiates on its official social media pages, there is persistent uncertainty about its effectiveness. Some posts elicit positive responses while others do not, which raises questions about what firms can do to improve social media user responses to FGC and achieve their business goals. This research demonstrates that the number of arguments (i.e., the product attributes listed in the promotional message) included in FGC tends to benefit utilitarian products more than hedonic ones, which has systematic effects on users' perceptions of and responses to the FGC. In the contexts of FGC, argument numerosity can be effective in mitigating the tension and uncertainty related to online shopping (due to psychological risk), but we argue this is only the case for utilitarian products and not for hedonic ones. To test our predictions, we present five studies that represent a mix of controlled experiments with fictitious Instagram posts and an automated text analysis, on Twitter, of thousands of real branded tweets. As predicted, the results demonstrate that argument numerosity reduces the perceived psychological risk (manifested in the uncertainty and tension associated with typical social commerce behaviors), which in turn enhances users' engagement with FGC and purchase intention—but only for utilitarian products. These findings have important implications for firms and managers looking for actionable insights on how to improve the effectiveness of their FGC.
Machine‐learning‐based integration of tumor microenvironment features predicting immunotherapy response
Authors: Luo Kunpeng , Liu Shuqiang , Cui Yunfu , Li Jinglin , Shen Xiuyun , Xu Jincheng , Jiang Yanan 
Published: January 2025

ABSTRACTImmunotherapy has revolutionized cancer treatment in recent years, yet non‐responsiveness of immunotherapy remains a challenge for cancer treatment. Therefore, the prediction method for potential clinical benefits of patients from immunotherapy is urgently needed. This study aims to develop an effective clinical practice assistance tool to evaluate the potential clinical benefits and therapy responsiveness of patients undergoing immunotherapy. We developed an immunotherapy resistance score (IRS), which performed well compared with conventional immunotherapy response indicators across different immunotherapy cohorts. Tumor microenvironment (TME) analysis showed that both immune and nonimmune features collectively impact immunotherapy responsiveness. Thus, IRS was constructed based on the TME features using machine learning approaches. The clinical application potential of IRS has been demonstrated in our in‐house Harbin Medical University (HMU) cohort and an external validation cohort. Furthermore, we analyzed the correlation between IRS and pathways related to cancer therapy targets to explore the application potential of IRS in comprehensive cancer therapy. In conclusion, IRS is a robust tool for predicting patient immunotherapy prognosis, which has great potential to promote precise clinical therapy.
Global Dynamics of a Multiscale Immuno‐Cholera Transmission Model With Bacterial Hyperinfectivity on Complex Networks
Authors: Cheng Xinxin , Wang Yi , Huang Gang 
Published: January 2025

ABSTRACTThe spread of cholera at the population level depends on the immunological characteristics of pathogens at the individual level. In addition, contact heterogeneity among individuals plays a significant role in cholera transmission. In this paper, we construct a multiscale coupled immuno‐cholera model considering waning vaccine‐induced immunity and hyperinfectious vibrios and utilize a nested approach to bridge within‐host vibrio evolution and between‐host cholera transmission on complex networks. The basic reproduction numbers and for the within‐ and between‐host models are derived, respectively, and is validated to serve as a sharp threshold between extinction and persistence of cholera. Specifically, the global asymptotic stability of each feasible equilibrium for the between‐host system is established by formulating appropriate Lyapunov functionals. Numerical simulations are performed to assess the influences of within‐host vibrio dynamics and network topology on between‐host cholera transmission dynamics. The results show that the equilibrium level of total infected individuals is a nonmonotonic function of vibrio growth rate, implying that hampering within‐host vibrio growth by drug treatment during the outbreak could alter the long‐term outcomes of cholera. Furthermore, the heterogeneity of network degree distributions increases the risk of cholera outbreaks, suggesting that isolation and supervision for infected individuals with high degrees are effective measures to prevent and control cholera transmission.
Special Affine Fourier Transform on Tempered Distribution and Its Application
Authors: Kumar Manish , Bhawna  
Published: January 2025

ABSTRACTThe main aim of this work is to develop a theoretical framework for generalized pseudo‐differential operators involving the special affine Fourier transform (SAFT), associated with a symbol . Some important properties of the SAFT are established, and it is proved that the product of two generalized pseudo‐differential operators is shown to be a generalized pseudo‐differential operator. Further, we explore the practical applications of the SAFT in solving generalized partial differential equations, such as the generalized telegraph and wave equations, providing closed‐form solutions. Furthermore, graphical visualizations for these solutions are illustrated via MATLAB R2023b.
Development and implementation of a Sezer gastrostomy care bundle using the Knowledge to Action framework
Authors: Sezer Ceren Rana Elcin , Talas Melek Serpil , Akcay Kezban , Basar Fatma , Halil Meltem 
Published: January 2025

AbstractBackgroundThis project aimed to develop an evidence‐based nursing care bundle after gastrostomy feeding tube insertion and implement it into clinical practice using the Knowledge to Action (KTA) framework.MethodsThis mixed‐method design project was conducted in a university hospital between December 2021 and June 2022. The project was carried out in four phases: (1) development of an evidence‐based care bundle, (2) education for care bundle training, (3) implementation of the care bundle, (4) evaluation of the care bundle. Nurses’ compliance with bundles was measured using All‐or‐None measurement. The analysis of the qualitative interview conducted was performed using the content analysis method of Graneheim and Lundman.ResultsThe developed Sezer gastrostomy care bundle consists of three parameters (peristomal area care, tube feeding, and medication administration through the feeding tube) and a total of 14 elements to be applied by nurses under these parameters. Compliance rates for peristomal area care, tube feeding, and medication administration through feeding tube parameters were 100%, 98.66%, and 98.66%, respectively. Two themes and six subthemes emerged: (1) reflection of using the Sezer gastrostomy care bundle on nursing care and (2) adoption of Sezer gastrostomy care bundle.ConclusionThe gastrostomy care bundle was developed in accordance with the Institute of Healthcare Improvement's recommendations. The KTA framework provided an appropriate structure to transform evidence into practice, meticulously address barriers, evaluate outcomes, and ensure sustainability. The project found that nurses complied with all its parameters. Studies evaluating the effect of the gastrostomy care bundle on patient outcomes are recommended.
Stroke and associated comorbidities in Southeast Asian countries
Authors: Datta Aishika , Akundi Soumya , Wagh Kaveri , Bhurle Gangadhar , Sarmah Deepaneeta , Sharma Arvind , Shah Sudhir , Borah Anupom , Saraf Shailendra , Bhattacharya Pallab 
Published: January 2025

AbstractStroke, a leading cause of mortality and morbidity worldwide, is a complex cerebrovascular disease. Stroke risk factors are diverse, encompassing age, sex, and ethnicity. Comorbid conditions, including hypertension, hyperglycemia, hyperlipidemia, and atrial fibrillation, exacerbate stroke outcomes, contributing to the overall stroke burden within populations. In addition to these factors, lifestyle‐related diseases can impact individuals across all age groups, and often include as comorbidities linked to stroke. Socioeconomic conditions, healthcare access, and the quality of clinical data significantly influence the prevalence of comorbidities. Asia, the largest continent and home to 60% of the world's population, includes many developing nations undergoing diverse economic transitions. In Southeast Asian countries, stroke prevalence is high, imposing a substantial burden on healthcare systems and economies. Research disparities in stroke are often attributed to insufficient demographic data on comorbidities. Hence, the review discusses all previously published results of hospital‐based studies and data from national registries. It has been noticed that due to insufficient documentation on stroke‐related comorbidities in various developing countries of Southeast Asia, stroke management becomes difficult. Therefore, this review aims to discuss the association between various comorbidities and stroke, with special emphasis on the incidence and prevalence of stroke burden in Southeast Asian countries.
Standard Versus Reduced Hydration to Improve Elimination of High‐Dose Methotrexate in Pediatric Patients: A Controlled Crossover Trial
Authors: Noda Cady , Gwaltney Lindsey , Sabo Roy , Lo Megan , Schefft Matthew 
Published: January 2025

ABSTRACTBackgroundHydration and urine alkalinization are the mainstays for the prevention of methotrexate‐induced nephrotoxicity. Current oncology protocols recommend pediatric patients who are administered high‐dose methotrexate (HDMTX) to be aggressively hydrated with an alkaline solution, which may lead to overhydration. This pilot study sought to determine whether reduced posthydration results in a shorter time to methotrexate elimination without increasing adverse effects.MethodsA prospective randomized controlled crossover study design of pediatric patients with acute lymphoblastic leukemia was performed. Patients were randomized to begin with standard or reduced volume intravenous fluids. Over the course of four cycles of HDMTX, patients alternated between the standard rate of 125 mL/m2/h and a reduced volume rate of 62.5 mL/m2/h. The primary endpoint was the time from the start of HDMTX to a serum methotrexate concentration less than 0.1 µmol/L.ResultsData from 37 HDMTX courses were analyzed in 10 patients aged 1–17 years. The median time to methotrexate elimination was similar between the standard and reduced hydration regimens at 71.7 h (60.8–115.6 h) versus 72.9 h (59.9–132 h, p value = 0.6539). There was no difference in the change from baseline to maximum creatinine (10% vs. 18.9%, p value = 0.6566), maximum weight gain (0.7 kg vs. 0.4 kg, p value = 0.0967), or rates of severe mucositis between hydration regimens.ConclusionReduced posthydration appeared to be safe and provided similar time to HDMTX elimination. A multicenter study is indicated to confirm the use of reduced hydration to optimize supportive care in pediatric patients administered HDMTX.Trial Registration: NCT03964259.
Community‐Based Participatory Research to Address the Disproportionate Burden of Breast Cancer in Black Women
Authors: Hailu Helen , Gay Starla , Chen Wei‐ting , Tuttle Chiquita , Waugh Juanita , Guillory Regina , Williams‐Omenka Lenora , Love Barakah , Hollis Taylor , Spinzi Stav , Rosas Lisa G. 
Published: January 2025

ABSTRACTObjectiveBlack/African American women with breast cancer have disproportionately higher mortality rates and report experiencing a lower quality of life during survivorship compared to non‐Hispanic white women. Despite support for the integration of peer navigation in cancer care and survivorship to address these inequities, Black/African American women often have limited access to culturally tailored peer navigation programs. We aimed to investigate the unique needs and strengths of Black/African American women with breast cancer and survivors to inform the development of a culturally tailored peer navigation program for Black/African American women.MethodsWe developed a community‐university partnership based on best practices of community‐based participatory research. The partnership conducted storytelling sessions with Black/African American survivors of breast cancer and their caregivers and key informant interviews with community partners and applied thematic analysis.ResultsA total of 14 survivors and 4 caretakers took part in storytelling sessions and 6 community partners took part in key informant interviews. Themes from the storytelling sessions included spirituality, social support, information seeking, and relationship with care team. These themes were then incorporated into developing the theoretical basis, structure, and content of the BLACC peer navigation program. The key informant interviews were instrumental in building new partnerships to support the implementation of the peer navigation program.ConclusionsThe community‐university partnership successfully identified the unique needs and strengths of Black/African American women who either had breast cancer or were survivors of breast cancer, identified valuable resources, and secured buy‐in from community leaders to develop a comprehensive peer navigation program.
Evaluation of Low‐Pressure Microwave Oxygen Plasma as an Ecofriendly Way to Control Three of the Most Important Pests of Stored Date Fruits Infesting Egyptian Cultivar Siwi
Authors: Zinhoum Rasha A. , El‐Shafei W. K. M. , Elashry S. 
Published: January 2025

ABSTRACTInsect pests in stored date fruits lead to significant economic losses, traditionally managed by chemical insecticides that harm the environment. This study explores low‐pressure microwave oxygen plasma treatments as an alternative pest control method against pests like Polda interpunctelia, Ephestia cautella, and Oryzaephilus surinamensis. A 20 s treatment achieved 100% mortality for all species without any adult emergence. Sensory evaluations showed no significant differences in taste, color, texture, odor, or overall acceptability between treated and untreated date fruits, indicating that the plasma treatment preserves fruit quality. Scanning electron microscopy revealed structural damage to the pests, whereas the Siwi cultivar date fruits remained unaffected. The findings suggest that this plasma treatment is an effective and environmentally friendly alternative to chemicals.