bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bregje de Vries en Ditte Lockhorst: Kristallisatie: de kunst van het belichten van complexe vraagstukken door onderzoek
Authors: de Vries Bregje , Lockhorst Ditte 
Published: February 2024

Kristallisatie: de kunst van het belichten van complexe vraagstukken door onderzoek
Om een beleidsvraagstuk ‘in volle omvang’ te kunnen adresseren, is het nodig het vanuit meerdere invalshoeken te belichten. Kristallisatie is een onderzoeksbenadering die dit doet. De benadering vindt haar oorsprong in de gedragswetenschappen en stelt zich een beleidsvraagstuk voor als een kristal met veel vlakjes. We beschrijven de twee uitgangspunten van kristallisatie – multiperspectiviteit en dialoog – en vertalen deze naar richtlijnen voor (beleids)onderzoek. We illustreren vervolgens de toepassing van de benadering met een onderzoek naar toekomstbestendig leraarschap, waarin we door de inzet van zeven onderzoeksbouwstenen en het betrekken van diverse groepen belanghebbenden in dialoog zowel theoretische als praktische inzichten over het vraagstuk ontwikkelden. We besteden in onze aanpak specifiek aandacht aan de combinatie van wetenschap en kunst die kristallisatie nastreeft als een effectieve manier om multiperspectiviteit in beeld te brengen en professionele dialoog te voeden. We laten in illustraties van de toepassing van kristallisatie zien dat de benadering met name van waarde kan zijn voor beleidsonderzoekers die ernaar streven doelgroepen bij de ontwikkeling en implementatie van nieuw beleid te betrekken of die in de fasen van ex durante of ex post evaluatie op zoek zijn naar belevingsgerichte aspecten van beleid.
Pengaruh Kualitas Layanan Front Office terhadap Minat untuk Berkunjung di DPMPTSP Kota Depok
Authors: Indri Hermawaty Noorsamsu  , Sri Hermawati  
Published: February 2024

The purpose was to determine the effect of service quality on return visit interest through community satisfaction. This research method quantitative survey type. The object is service quality on public satisfaction and interest in visiting again. The research subjects were people who conducted SIUP licensing at the front office of the One- Stop Investment and Integrated Services Office (DPMPTSP) located in Depok City. The sampling technique random sampling. The sample amounted to 120 respondents. The results showed that service quality had a significant effect on community satisfaction and interest in visiting again. Public satisfaction has a significant effect on interest in visiting again. All three variables have a significant value <0.05, which means H0 is rejected and Ha is accepted.
The provision of general surgery in rural Australia: a narrative review
Authors: Paynter Jessica , Qin Kirby R , Brennan Janelle , Hunter‐Smith David J , Rozen Warren M 
Published: February 2024

Summary

Rural surgery is most commonly provided by general surgeons to the 29% of people (7 million) living in rural Australia.

The provision of rural general surgery to enable equitable and safe surgical care for rural Australians is a multifaceted issue concerning recruitment, training, retention, surgical procedures and surgical outcomes.

Sustaining the rural general surgical workforce will be dependent upon growing an increased number of resident rural general surgeons, as well as changed models of care, with a need for ongoing review to track the outcomes of these changes.

To increase recruitment, rural general surgical training must improve to be less stressful for trainees and to be incorporated alongside a rural‐facing generalist curriculum.

Rural general surgical outcomes (excluding some oncology conditions) achieve comparable results to metropolitan centres.

Access to, and outcomes of, surgical oncology services continues to be inequitable for rural Australians and should be a major focus for improved service delivery.
Randomized trial of early detection and treatment of postpartum hemorrhage
Authors: Oyoo Polycarp , Zahida Qureshi  , Alfred Osoti  , George Gwako  , Jennifer Okore  , Jim Kelly Mugambi  , I. Gallos  , A. Devall  , J. Martin  , L. Middleton  , L. Beeson  , H. Galadanci  , F. Alwy Al-beity  , G.J. Hofmeyr  , N. Moran  , S. Fawcus  , L. Sheikh  
Published: February 2024

Background: Delays in the detection or treatment of postpartum hemorrhage can result in complications or death. A blood-collection drape can help provide objective, accurate, and early diagnosis of postpartum hemorrhage, and delayed or inconsistent use of effective interventions may be addressed by a treatment bundle.
Methods: We conducted an international, cluster-randomized trial to assess a multicomponent clinical intervention for postpartum hemorrhage in vaginal delivery patients. The intervention included a calibrated blood-collection drape for the early detection of postpartum hemorrhage and a bundle of first-response treatments (uterine massage, oxytocic drugs, tranexamic acid, intravenous fluids, examination, and escalation), supported by an implementation strategy (intervention group). Hospitals in the control group provided usual care. The primary outcome was a composite of severe postpartum hemorrhage (blood loss, ≥1000 ml), laparotomy for bleeding, or maternal death from bleeding. The key secondary implementation outcomes were the detection of postpartum hemorrhage and adherence to the treatment bundle.
Results: 80 secondary-level hospitals across Kenya, Nigeria, South Africa, and Tanzania, in which 210,132 patients underwent vaginal delivery, were randomly assigned to the intervention group or the usual-care group. Among hospitals and patients with data, a primary outcome event occurred in 1.6% of the patients in the intervention group compared with 4.3% of those in the usual-care group (risk ratio, 0.40; 95% confidence interval [CI], 0.32-0.50; P<0.001). Postpartum hemorrhage was detected in 93.1% of the patients in the intervention group and 51.1% of those in the usual-care group (rate ratio, 1.58; 95% CI, 1.41-1.76), and the treatment bundle was used in 91.2% and 19.4% patients, respectively (rate ratio, 4.94; 95% CI, 3.88-6.28).
Conclusion: Early detection of postpartum hemorrhage and use of bundled treatment led to a lower risk of the primary outcome, a composite of severe postpartum hemorrhage, laparotomy for bleeding, or death from bleeding, than usual care among patients having vaginal delivery.

(Funded by the Bill and Melinda Gates Foundation; E-MOTIVE ClinicalTrials.gov number, NCT04341662).
Aprendizaje durante un programa de formación en simulación: una replicación conceptual
Authors: Losey Pelayo Cristina , Leppink Jimmie , Rojo Santos Elena , González Anillo Marta , Del Moral Ignacio , Maestre José María 
Published: February 2024

(1) Introduction: The widespread adoption of healthcare simulation as a teaching tool has led to a growth in training programs for simulation instructors. However, there are few studies documenting the effectiveness of these programs. The objective was to study the transformation experienced by participants in an on-site edition of a specific training program and compare the possible differences observed with a previously studied and published online edition of the same program. (2) Methods. The program consisted of a 15-day online interactive module, four 8-hour face-to-face days on site, and an individual online session with one of the instructors. Each day on-site resulted in individual written reflections that were categorized according to the learning themes described by Kolbe and Rudolph (2018). (3) Results: 25 subthemes were identified that include a total of 78 elements identified in the 38 responses of the participants, categorized according to five learning themes: notes to self, evaluations, metacognitions, anticipations of applications, and emotions. (4) Conclusion: A comparable professional development progression was identified between the on-site face-to-face (the current study) and online (the previously published study) format.
(1) Introducción: La adopción generalizada de la simulación en salud como herramienta docente ha dado lugar a un crecimiento de los programas de formación para instructores de simulación. Sin embargo, son escasos los estudios documentando la eficacia de estos programas. El objetivo fue estudiar la transformación experimentada por los participantes en una edición in situ de un programa de formación específico y comparar las posibles diferencias observadas con una edición online del mismo programa, estudiada y publicada anteriormente. (2) Métodos. El programa consistió en un módulo interactivo online de 15 días, 4 días in situ de 8 horas y una sesión individual online con uno de los instructores. Cada día in situ resultó en reflexiones escritas individuales, que se categorizaron según los temas de aprendizaje descritos por Kolbe y Rudolph (2018). (3) Resultados: Se identificaron 25 subtemas que agrupan un total de 78 elementos identificados en las 38 respuestas de los participantes, categorizadas según cinco temas de aprendizaje: notas para uno mismo, evaluaciones, metacogniciones, anticipaciones de aplicaciones, y emociones. (4) Conclusión: Se identificó una progresión del desarrollo profesional comparable entre el formato presencial in situ (el estudio actual) y online (el estudio publicado anteriormente).
Pendekatan dalam Integrasi Kurikulum Pondok Pesantren dan Madrasah: Studi di Pondok Pesantren Al-Hikmah Bandar Lampung
Authors: Azmi Muhamad , Muhammad Akmansyah  , Amiruddin  
Published: February 2024

Curriculum integration in islamic education refers to involves integrating the concepts and content of religius learning and general learning. This study outlines the integration of salaf Islamic boarding school education with the madrasah curriculum at Pondok Pesantren Al-Hikmah Bandar Lampung. This type of research is a type of qualitative research and data collection technique used snowball sampling for interviews, accompanied by observation and documentation. The data were analyzed using integrative and interactive techniques. This study found that the Islamic integrated curriculum in Pondok Pesantren Al-Hikmah Bandar Lampung was applied by combining the national curriculum with salaf islamic boarding school (pesantren salaf) education. The integration of madrasa and salaf Islamic boarding school curriculum is to open ourselves to the progress of the times where students are equipped with religious knowledge and general science. Implementation of curriculum integration with a social-religious approach by inserting religious moderation values in learning.
Mental Health Interventions among People Living with HIV/AIDS in Nigeria: A Scoping Review
Authors: Asogun D. , Obodeh C. , Okhihan I. , Aziba T. , Edogun J. , Oisakede E. O. , Akhaine J. 
Published: February 2024

Background: People who are living with HIV/AIDS (PLWHA) often face numerous mental health challenges, such as depression and anxiety disorders. The objective of this scoping review was to systematically analyse and synthesise the existing literature on mental health interventions available for PLWHA in Nigeria.
Methods: To conduct this review, a comprehensive search of reputable sources including PUBMED, Google Scholar, Science Direct, Hinari, and African Journal Online (AJOL) was performed. Adhering to the Preferred Reporting Items for Systematic Reviews and Meta-Analysis extension for Scoping Reviews (PRISMA-ScR) reporting guidelines, a total of 6 studies were identified, spanning from 2007 and 2021, that focused on interventions addressing adverse mental health conditions among PLWHA.
Results: The studies were conducted in three different regions across Nigeria, with the highest number of studies conducted in the South-West region (3), followed by the South East region (2), and the North Central region (1). Among the mental health conditions addressed in these studies, depression was the most prevalent (4 out of 6 studies, or 66.7%), followed by depression co-occurring with other mental health conditions (3 out of 6 studies, or 50%). The most commonly utilised interventions in the reviewed studies were cognitive behavioural therapy (CBT) and aerobic exercise delivery, each accounting for 33.3% of the interventions. All of the studies reported positive outcomes in terms of participants' mental health. The majority of the studies (83.3%) involved professional counsellors administering the mental health interventions, followed by physiotherapists (33.3%) and psychotherapists (33.3%).
Conclusions: The findings of this review indicate that there is a significantly limited number of implemented interventions addressing the various forms of mental distress experienced by PLWHA, particularly in high prevalence areas of Nigeria. This highlights a crucial research gap and emphasises the need for more interventions that specifically address the mental health needs of PLWHA in Nigeria, taking into consideration the unique challenges and opportunities present in the country.
A Review on Organic Farming in India
Authors: Cha Vikas Moirangthem , Elish Thokchom , Sina N , Mishra Saket , Kushwaha Akhilesh , Ekka Shashi Kant , Kujur Reena 
Published: February 2024

Organic horticulture is a dynamic and sustainable approach to cultivating plants that prioritizes environmental health, biodiversity, and human well-being. This combination of high-yielding production technology has helped the country develop a food surplus as well as contributing to concerns of soil health, environmental pollution, pesticide toxicity, and sustainability of agricultural production. Alternatives for managing pests and diseases in organic farming mostly focus on preventive methods as opposed to curative therapies, which are founded on ecologically safer management techniques. The priority has been placed on maintaining the ecosystem’s health, allowing plants to become resistant to insect pests and illnesses.
Comparison of the Patient Demographics, High-Resolution Computed Tomography Features of the Pulmonary Ground-Glass Opacity and Its Diagnostic Value Analysis
Authors: Fan Sheng , Zhu Xiaolei , Lin Hui , Chen Junhai , Li Lintao , Shi Sien 
Published: February 2024

Introduction
Pulmonary ground-glass opacity (GGO) observed on computed tomography (CT) is widely regarded as a diagnostic feature of lung adenocarcinoma; however, a significant radiological predictive sign remains controversial. In this retrospective study, we conducted a comprehensive analysis of 206 patients with GGO to establish a correlation analysis model between CT images and diagnosis of GGO nodules.

Methods
Histopathologic specimens were obtained from 206 patients (130 women, 76 men; age range 24–77). The clinical data, pathologic findings, and thin-section CT features of solid, pure GGO (pGGO), and mixed GGO (mGGO) nodules were compared using rigorous statistical methods, such as t-test, Fisher’s exact test, or univariate logistic regression analysis.

Results
Significant differences were observed among the 3 groups in terms of patient demographics, including gender (P = 0.016), smoking history (P = 0.002), and nodule size (P = 0.002). Morphologic CT characteristics, such as the presence of spiculated sign, lobulated sign, vascular sign, bubble-lucency sign, or pleural retraction, exhibited significant differences among the solid nodule, pGGO, and mGGO groups. However, no significant differences were observed in terms of air-bronchogram sign. Notably, the incidence of malignancy was significantly higher in pGGO nodules (76.52%) than in solid (48.48%) and mGGO (73.86%) nodules. Patients with mGGO had up to 2.988 times higher hazard of malignant lesions than those with solid nodules [P = 0.036, hazard ratio (HR) = 2.988]. Similarly, the hazard of malignant lesions was 2.941 times higher in patients with pGGO than in those with solid nodules (P = 0.007, HR = 2.941).

Conclusion
Clinical, pathological, and thin-section CT features of solid, pGGO and mGGO nodules were found to be significantly different. Based on our comprehensive analysis, patients presenting with a mGGO or pGGO on CT scans were more likely to be diagnosed with lung cancer.
Maintaining knowledge management systems: A strategic imperative
Authors: Desouza Kevin C. , Awazu Yukika 
Published: March 2005

AbstractMost organizations have reported dismal returns on their investments in knowledge portals—Intranet Web sites aimed at enabling the storage and exchange of explicit knowledge artifacts. In our research, we were surprised to find that knowledge workers have for the most part abandoned the use of knowledge portals. Moreover, in cases where they do turn to knowledge portals they use it as a last resort. In this brief communication, we call attention both to research and practice to help transform current knowledge portals to ones that are more sensitive to the issues faced by practitioners. To this end, we will elaborate on the need to pay attention to maintenance of knowledge management portals.
GC‐MS analysis of penta‐ and tetra‐cyclic triterpenes from resins of Pistacia species. Part II. Pistacia terebinthus var. Chia
Authors: Assimopoulou A. N. , Papageorgiou V. P. 
Published: March 2005

AbstractPistacia species contain oleoresins with bioactive triterpenes. In this study triterpenes, including minor components, were identified and quantified in both neutral and acidic fractions of Pistacia terebinthus var. Chia resin, grown exclusively in Chios island (Greece), collected traditionally, as well as using stimulating agents (liquid collection). It was proved that these two resin samples were composed of several different minor triterpenes, while major constituents were similar but in different proportions. Compounds that differentiated two resin samples of P. lentiscus and P. terebinthus var. Chia, both traditionally collected, were detected, in order to identify the nature of resins present in archaeological materials. In the traditionally collected resin, 37 triterpenes were identified, 12 in the acidic and 25 in the neutral fraction. In the liquid collection resin 10 compounds were identified in the acidic and 23 in the neutral fraction, while 16 compounds were not contained in the traditionally collected resin. The main triterpenes in both resin samples collected traditionally and using stimulating agents were: isomasticadienonic acid (23.6 and 26.3% w[sol ]w of the triterpenic fraction, respectively), 28‐norolean‐17‐en‐3‐one (16.3 and 17.5% w[sol ]w of the triterpenic fraction, respectively) and masticadienonic acid (5.8 and 6.0% w[sol ]w of the triterpenic fraction). In this study the qualitative and quantitative composition of triterpenes was compared in the Pistacia lentiscus and P. terebinthus var. Chia resin samples collected with the traditional and new liquid techniques, and also triterpenes in resins of P. terebinthus obtained by the traditional technique and using stimulating agents. The aim of the study was also to examine whether the collection technique influenced the triterpenes contained in P. terebinthus var. Chia resin samples. Copyright © 2005 John Wiley & Sons, Ltd.
Tongue and tonsil carcinoma
Authors: Shiboski Caroline H. , Schmidt Brian L. , Jordan Richard C. K. 
Published: March 2005

AbstractBACKGROUNDAn increasing incidence of oral carcinoma among young adults has been reported in the U.S. and Europe. Although the association between human papillomavirus infection and tonsillar carcinoma is now well established, to the authors' knowledge little is known about incidence trends in tonsillar carcinoma among younger adults. The objective of the current study was to explore the trends in both oral cavity and pharyngeal squamous cell carcinoma (SCC) in younger U.S. populations, in particular tongue and tonsillar SCC.METHODSUsing the 1973–2001 Surveillance, Epidemiology and End Results (SEER) database, we computed age, race, and site‐specific trends of oral and pharyngeal (excluding nasopharynx) carcinoma incidence rates. The percent change (PC) and annual percent change (APC) were computed to explore trends in incidence rates over time.RESULTSThere were 2262 SCC of the oral cavity and 1251 SCC of the pharynx reported to the SEER program from 1973 to 2001 in adults aged 20–44 years. There was a statistically significant increase in the incidence of oral tongue SCC (APC = +2.1; P < 0.001), base of tongue SCC (APC = +1.7; P = 0.04), and palatine tonsil SCC (APC = +3.9; P < 0.001) among younger white individuals, whereas the incidence of SCC in all other oral and pharyngeal sites decreased or remained constant.CONCLUSIONSThe increase in tonsil SCC incidence from 1973 to 2001 paralleled the increase in tongue SCC, whereas SCC in all other oral and pharyngeal sites remained constant or decreased. This may suggest similar etiologic factors for SCC affecting the palatine tonsils and tongue in younger populations. Cancer 2005. © 2005 American Cancer Society.
Development of human visual cortex: A balance between excitatory and inhibitory plasticity mechanisms
Authors: Murphy Kathryn M. , Beston Brett R. , Boley Philip M. , Jones David G. 
Published: March 2005

AbstractFormation of neural circuitry in the developing visual cortex is shaped by experience during the critical period. A number of mechanisms, including N‐methyl‐D‐aspartate (NMDA) receptor activation and γ‐aminobutyric acid (GABA)‐mediated inhibition, are crucial in determining onset and closure of the critical period for visual plasticity. Animal models have shown that a threshold level of tonic inhibition must be reached for critical period plasticity to occur and that NMDA receptors contribute to Hebbian synaptic plasticity in the developing visual cortex. There are a number of developmental changes in these glutamatergic and GABAergic mechanisms that have been linked to plasticity; however, those changes have been shown only in animal models, and their development in the human visual cortex is not known. We have addressed this question by studying the expression of the major glutamatergic receptors, GABAA receptors, and glutamic acid decarboxylase (GAD) isoforms during the first 6 years of postnatal development of human visual cortex. There are significant changes in the expression of these proteins during postnatal development of human visual cortex. The time course of the changes is quite prolonged and suggests that it may set the pace for the prolonged critical period in human visual development. The changes also affect the nature of spatial and temporal integration in visual cortical neurons and thereby contribute to the maturation of visual functions. © 2005 Wiley Periodicals, Inc. Dev Psychobiol 46: 209–221, 2005.
An Amperometric Enzyme Biosensor Fabricated from Polyaniline Nanoparticles
Authors: Morrin Aoife , Ngamna Orawan , Killard Anthony J. , Moulton Simon E. , Smyth Malcolm R. , Wallace Gordon G. 
Published: March 2005

AbstractThe biosensor described here uses a novel aqueous‐based nanoparticulate polyaniline (PANI), doped with dodecylbenzenesulfonic acid (DBSA). The nanoparticles were applied to a glassy carbon electrode surface by electrodeposition techniques, and horseradish peroxidase (HRP) was subsequently electrostatically adsorbed to the nanoparticle‐modified surface. This biosensor format was demonstrated for H2O2 sensing. Electrodeposited polymer nanoparticles resulted in highly ordered conductive nanostructured films, which were examined by scanning electron microscopy (SEM), atomic force microscopy (AFM), profilometry and spectroelectrochemistry. The surface of the films were characterized by a uniform array of nanoparticulate PANI (nanoPANI/DBSA) nodules and were shown to have a thickness of 350 nm. Physical techniques have shown that the nanofilms possess properties which allow for uniform electrostatic adsorption of protein to take place. This effective biosensor format, exhibits higher signal‐to‐background ratios and shorter response times than previous PANI biosensor configurations.