bluuebunny/crossref_metadata_2025_split huggingface dataset:
Evaluation of the in vitro effects of concentrations of antibiotics on three Enterobacteriaceae isolates
Authors: Delik Eda , Eroğlu Berfin , Tefon-Öztürk Burcu Emine 
Published: January 2024

AbstractDue to the misuse and overuse of antibiotics, bacteria are now exposed to sub-minimum inhibitory concentrations (sub-MICs) of antibiotics in various environments. In recent years, exposure of bacteria to sub-MICs of antibiotics has led to the widespread emergence of antibiotic-resistant bacteria. In this study, three bacterial species from the Enterobacteriaceae family (Raoultella ornithinolytica, Pantoea agglomerans and Klebsiella quasivariicola) were isolated from water. The antibiotic susceptibility of these bacteria to 16 antibiotics was then investigated. The effects of sub-MICs of four selected antibiotics (kanamycin, chloramphenicol, meropenem, and ciprofloxacin) on the growth, biofilm formation, surface polysaccharide production, siderophore production, morphology, and expression of the translational/transcriptional regulatory transformer gene rfaH of these bacteria were analysed. The MICs of kanamycin, chloramphenicol, meropenem, and ciprofloxacin were determined to be 1, 2, 0.03 and 0.03 µg/mL for R. ornithinolytica; 0.6, 6, 0.03 and 0.05 µg/mL for P. agglomerans; and 2, 5, 0.04 and 0.2 µg/mL for K. quasivariicola. The growth kinetics and biofilm formation ability decreased for all three isolates at sub-MICs. The surface polysaccharides of R. ornithinolytica and P. agglomerans increased at sub-MICs. There was no significant change in the siderophore activities of the bacterial isolates, with the exception of MIC/2 meropenem in R. ornithinolytica and MIC/2 kanamycin in K. quasivariicola. It was observed that the sub-MICs of meropenem and ciprofloxacin caused significant changes in bacterial morphology. In addition, the expression of rfaH in R. ornithinolytica and K. quasivariicola increased with the sub-MICs of the selected antibiotics.
Evolutionary preservation of CpG dinucleotides in RAG1 may elucidate the relatively high rate of methylation-mediated mutagenesis of RAG1 transposase
Authors: Fawzy Mariam M. , Nazmy Maiiada H. , El-Sheikh Azza A. K. , Fathy Moustafa 
Published: January 2024

AbstractRecombination-activating gene 1 (RAG1) is a vital player in V(D)J recombination, a fundamental process in primary B cell and T cell receptor diversification of the adaptive immune system. Current vertebrate RAG evolved from RAG transposon; however, it has been modified to play a crucial role in the adaptive system instead of being irreversibly silenced by CpG methylation. By interrogating a range of publicly available datasets, the current study investigated whether RAG1 has retained a disproportionate level of its original CpG dinucleotides compared to other genes, thereby rendering it more exposed to methylation-mediated mutation. Here, we show that 57.57% of RAG1 pathogenic mutations and 51.6% of RAG1 disease-causing mutations were associated with CpG methylation, a percentage that was significantly higher than that of its RAG2 cofactor alongside the whole genome. The CpG scores and densities for all RAG ancestors suggested that RAG transposon was CpG denser. The percentage of the ancestral CpG of RAG1 and RAG2 were 6% and 4.2%, respectively, with no preference towards CG containing codons. Furthermore, CpG loci of RAG1 in sperms were significantly higher methylated than that of RAG2. In conclusion, RAG1 has been exposed to CpG mediated methylation mutagenesis more than RAG2 and the whole genome, presumably due to its late entry to the genome later with an initially higher CpG content.
Transient breathing dynamics during extinction of dissipative solitons in mode-locked fiber lasers
Authors: Yuan Zichuan , Luo Si , Dai Ke , Yao Xiankun , Tao Chenning , Ling Qiang , Zhang Yusheng , Guan Zuguang , Chen Daru , Cui Yudong 
Published: January 2024

Abstract
The utilization of the dispersive Fourier transformation approach has enabled comprehensive observation of the birth process of dissipative solitons in fiber lasers. However, there is still a dearth of deep understanding regarding the extinction process of dissipative solitons. In this study, we have utilized a combination of experimental and numerical techniques to thoroughly examine the breathing dynamics of dissipative solitons during the extinction process in an Er-doped mode-locked fiber laser. The results demonstrate that the transient breathing dynamics have a substantial impact on the extinction stage of both steady-state and breathing-state dissipative solitons. The duration of transient breathing exhibits a high degree of sensitivity to variations in pump power. Numerical simulations are utilized to produce analogous breathing dynamics within the framework of a model that integrates equations characterizing the population inversion in a mode-locked laser. These results corroborate the role of Q-switching instability in the onset of breathing oscillations. Furthermore, these findings offer new possibilities for the advancement of various operational frameworks for ultrafast lasers.

Graphical abstract
Production and evaluation of novel functional cream cottage cheese fortified with bovine colostrum and probiotic bacteria
Authors: Abdeen El-Sayed M. , Hamed Ahmed M. , Ismail Hesham A. 
Published: January 2024

AbstractNutrient-dense colostrum can be employed as a functional food ingredient. This work aimed to produce novel functional probiotic Cream cottage cheese (FPC) using probiotic (ABT) culture and bovine colostrum powder (BCP) at levels of 1, 2, and 3%. Physicochemical and functional properties (antioxidant activity, fatty acid profile, and antibacterial activity) were analyzed. The outcome revealed that hardness, cohesiveness, and gumminess were increased while springiness and chewiness were decreased for the treated cheeses. In FPC, medium-chain fatty acids were the predominant forms, followed by short- and long-chain fatty acids, polyunsaturated (PUFA), and small amounts of monounsaturated (MUFA). The antioxidant activity of all the cheese samples was significantly (P < 0.05) increased by increasing the quantity of colostrum powder and lengthening storage time. Color parameters were influenced by enrichment with BCP, whether in fresh or stored samples. With the addition of BCP, the growth of lactic acid bacteria and Bifidobacteria was enhanced, whereas that of pathogenic bacteria, mold and yeast, and coliform groups was inhibited. Cheeses fortified with 2% BCP had significantly higher score values than those in the other treatments. Therefore, it could be concluded that cottage cheese fortified with 2% BCP has high nutritional value and health benefits.
Heat Source Model Development for Thermal Analysis of Laser Powder Bed Fusion Using Bayesian Optimization and Machine Learning
Authors: Kusano Masahiro , Watanabe Makoto 
Published: January 2024

AbstractTo understand the correlation between process, structures, and properties in laser powder bed fusion (L-PBF), it is essential to use numerical analysis as well as experimental approaches. A finite element thermal analysis uses a moving heat source model represented as a volumetric heat flux to simulate heat input by laser. Because of its computational efficiency, finite element thermal analysis is suitable for iterative procedures such as parametric study and process optimization. However, to obtain valid simulated results, the heat source model must be calibrated by comparison with experimental results for each laser scanning condition. The need for re-calibration limits the applicable window of laser scanning conditions in the thermal analysis. Thus, the current study developed a novel heat source model that is valid and precise under any laser scanning condition within a wide process window. As a secondary objective in the development, we quantitatively evaluated and compared the four heat source models proposed to date. It was found that the most suitable heat source model for the L-PBF is conical one among them. Then, a multiple linear regression analysis was performed to represent the heat source model as a function of laser power and scanning velocity. Consequently, the thermal analysis with the novel model is valid and precise within the wide process window of L-PBF.
Qualitative and quantitative characteristics of CEUS for renal cell carcinoma and angiomyolipoma: a narrative review
Authors: Dipinto Piervito , Canale Vittorio , Minelli Rocco , Capuano Marco Alex , Catalano Orlando , Di Pierro Giovanni Battista , Anceschi Umberto , Perdonà Sisto , Tufano Antonio 
Published: January 2024

AbstractIncidental findings of renal masses are increasing. However, a substantial portion of surgically treated renal masses turn out to be benign on histopathological examination. Thus, there is a clear need for improved pre-surgical assessment to minimize unnecessary invasive procedures. The challenge intensifies when distinguishing between renal cell carcinoma (RCC) and angiomyolipoma (AML) in renal lesions smaller than 4 cm with minimal adipose tissue. In such cases, contrast-enhanced ultrasound (CEUS) has emerged as a valuable diagnostic tool, by utilizing both qualitative and quantitative parameters. Quantitative measures offer objectivity, reliability, and reproducibility compared to qualitative parameters, enabling the characterization of RCC subtypes and differentiation from AML. Qualitative features as enhancement pattern, degree, and peak were less helpful in distinguishing triphasic minimal fat AML (TAML) from epithelioid AML (EAML), with the pseudocapsule sign potentially being the only distinguishing qualitative feature. The pseudocapsule sign was more frequently observed in ccRCCs (38.0%) than in AMLs (15.6%). Moreover, it was detected in 40.0% of EAMLs and 34.5% of ccRCCs but not in TAMLs due to similar growth patterns between EAMLs and low-grade ccRCCs. Quantitative measures such as the time-to-peak (TTP) ratio can further enhance diagnostic accuracy and also TOC ratio should be considered, as it was higher in clear cell RCCs (ccRCCs) and in EAMLs compared to TAMLs, indicating behavior similar to ccRCCs. However, CEUS remains an operator-dependent exam.
Research on Vibration Characteristics of a Flexible Vehicle-Ladder Track System
Authors: Wang Huan , Gu Aijun , Fan Qiang , Xing Xing , Liu Jingyu 
Published: January 2024

AbstractAs a means of vibration reduction, the ladder track has seen broad implementation in urban rail transit. However, issues such as increased vibration noise, rail corrugation, and fastener failure have been observed in certain sections of the ladder track during later operation. To investigate the mechanisms behind these phenomena and provide comprehensive insights into the system's response to various operational conditions, this study employed vehicle-track coupled dynamic theory to establish a three-dimensional finite element model of the flexible vehicle-ladder track system. The vibration transmission and dynamic response characteristics of the vehicle-ladder track system were analyzed. The findings revealed that the vehicle-track resonance and anti-resonance phenomena were more prominent in the medium- to low-frequency range. At specific frequencies, the wheelset exhibited various vibration modes, and the fastener force was found to closely correlate with the ladder vibration mode. Furthermore, the influence of speed on diverse components of the vehicle-ladder track system, in terms of maximum vibration and the dominant vibration frequency range, differed considerably. This study provides a more comprehensive and reasonable exploration of the modeling and dynamic behavior of vehicle-ladder track systems.
DB-GPT: Large Language Model Meets Database
Authors: Zhou Xuanhe , Sun Zhaoyan , Li Guoliang 
Published: January 2024

AbstractLarge language models (LLMs) have shown superior performance in various areas. And LLMs have the potential to revolutionize data management by serving as the "brain" of next-generation database systems. However, there are several challenges that utilize LLMs to optimize databases. First, it is challenging to provide appropriate prompts (e.g., instructions and demonstration examples) to enable LLMs to understand the database optimization problems. Second, LLMs only capture the logical database characters (e.g., SQL semantics) but are not aware of physical characters (e.g., data distributions), and it requires to fine-tune LLMs to capture both physical and logical information. Third, LLMs are not well trained for databases with strict constraints (e.g., query plan equivalence) and privacy-preserving requirements, and it is challenging to train database-specific LLMs while ensuring database privacy. To overcome these challenges, this vision paper proposes a LLM-based database framework (), including automatic prompt generation, DB-specific model fine-tuning, and DB-specific model design and pre-training. Preliminary experiments show that achieves relatively good performance in database tasks like query rewrite and index tuning. The source code and datasets are available at github.com/TsinghuaDatabaseGroup/DB-GPT.
In situ monitoring of stress corrosion at the Alloy 625|NaCl interface
Authors: Wu Fuli , Zhu Yongyan , Yuan Boyu , Li Liang 
Published: January 2024

AbstractDigital holography was used for in situ monitoring of the dynamic stress corrosion processes occurring at the Alloy 625|0.5 M NaCl interface. The introduction of elastic deformation to Alloy 625 through constant extension rate tensile loading increased the anodic and corrosion currents. These increases were attributed to the increased stress caused by elastic deformation, which increased the number of defects in the oxide film on the surface of Alloy 625 and promoted stress corrosion; this was verified by the fact that the accept density (NA) was nearly ten times greater with elastic deformation than without elastic deformation. Intergranular corrosion (IGC) was induced without elastic deformation. IGC induction occurred because chloride ions were readily adsorbed at the grain boundaries and were more active than the grain bodies. However, the application of elastic deformation induced cracks on the alloy surface to enhance stress corrosion, and it inhibited the development of IGC because the cracks were more susceptible to corrosion than the grain boundaries. In-line digital holography revealed that the cracks were initiated in a certain area and progressively advanced to adjacent areas with applied elastic tensile stress.
Local weak limit of preferential attachment random trees with additive fitness
Authors: Lo Tiffany Y. Y. 
Published: January 2024

AbstractWe consider linear preferential attachment trees with additive fitness, where fitness is the random initial vertex attractiveness. We show that when the fitnesses are independent and identically distributed and have positive bounded support, the local weak limit can be constructed using a sequence of mixed Poisson point processes. We also provide a rate of convergence for the total variation distance between the r-neighbourhoods of a uniformly chosen vertex in the preferential attachment tree and the root vertex of the local weak limit. The proof uses a Pólya urn representation of the model, for which we give new estimates for the beta and product beta variables in its construction. As applications, we obtain limiting results and convergence rates for the degrees of the uniformly chosen vertex and its ancestors, where the latter are the vertices that are on the path between the uniformly chosen vertex and the initial vertex.
Central limit theorem for a birth–growth model with poisson arrivals and random growth speed
Authors: Bhattacharjee Chinmoy , Molchanov Ilya , Turin Riccardo 
Published: January 2024

AbstractWe consider Gaussian approximation in a variant of the classical Johnson–Mehl birth–growth model with random growth speed. Seeds appear randomly in
$\mathbb{R}^d$
at random times and start growing instantaneously in all directions with a random speed. The locations, birth times, and growth speeds of the seeds are given by a Poisson process. Under suitable conditions on the random growth speed, the time distribution, and a weight function
$h\;:\;\mathbb{R}^d \times [0,\infty) \to [0,\infty)$
, we prove a Gaussian convergence of the sum of the weights at the exposed points, which are those seeds in the model that are not covered at the time of their birth. Such models have previously been considered, albeit with fixed growth speed. Moreover, using recent results on stabilization regions, we provide non-asymptotic bounds on the distance between the normalized sum of weights and a standard Gaussian random variable in the Wasserstein and Kolmogorov metrics.
Determinants of anxiety and depression among type 2 diabetes mellitus patients: A hospital-based study in Bangladesh amid the COVID-19 pandemic
Authors: Hossen Md. Toufik , Shuvo Suvasish Das , Mazumdar Sanaullah , Hossain Md. Sakhawot , Riazuddin Md. , Roy Deepa , Mondal Bappa Kumar , Parvin Rashida , Paul Dipak Kumar , Adnan Md. Moshiuzzaman 
Published: January 2024

Abstract
Anxiety and depression are common psychological disorders in patients with type 2 diabetes mellitus (T2DM), which was upsurging worldwide amid the COVID-19 pandemic. This study aimed to explore factors associated with anxiety and depression among T2DM patients in Bangladesh during the COVID-19 pandemic. A cross-sectional study was conducted among T2DM patients using face-to-face interviews. Anxiety and depressive symptoms were measured using the CAS and PHQ-9 scales. Outcomes were assessed including sociodemographic, lifestyle, anthropometric, and challenges of getting routine medical and healthcare access-related questions. The prevalence of anxiety and depressive symptoms were 29.8% and 22.7%, respectively. Regression analysis reported that males older than 50 years, illiterate, unemployed or retired, urban residents, below the recommended level of moderate to vigorous physical activity (MVPA), low dietary diversity score (DDS) and obese respondents were associated with higher odds of anxiety and depressive symptoms. Moreover, respondents with transport difficulties, unaffordable medicine, medicine shortages, close friends or family members diagnosed with COVID-19 and financial problems during COVID-19 had higher odds of anxiety and depressive symptoms than their counterparts, respectively. Our study suggests providing psychological support, such as home-based psychological interventions, and highlighting policy implications to ensure the well-being of T2DM patients in Bangladesh during the pandemic.
Croatian Homeland War Memorial Museums – Exhibiting Urbicides and Concentration Camps
Authors: Radonić Ljiljana 
Published: January 2024

AbstractRecently opened memorial museums and exhibitions in Croatia museumize the “Homeland War” of 1991 to 1995. This article examines the four major institutions, the Museum of the Homeland War in Karlovac as well as three sites in Vukovar: The Memorial Center for the Homeland War, the Memorial Hospital and the Ovčara Memorial Home. This first systematic site analysis compares 1) the overall narratives; 2) how enemy images from World War II are reactivated to demonize “the other”; 3) how women are represented in these war exhibitions; and 4) the topics that are left out. I argue that while there is still no national museum that includes war developments in all of the country, the two big institutions, the Museum in Karlovac and the Center in Vukovar, focus on the “defenders,” as the Croatian fighters are called – while in Karlovac strikingly marginalizing and at the Center completely omitting civilians. War here means (male) soldiers and weapons, while the other two institutions portray individual victims without discussing their biographies. In all sites, Serbs are depicted with reference to World War II: as Chetniks, running “concentration camps” who committed either “urbicide and culturocide” or a “holocaust” against Croats.
The population ecology of interest groups and counter-mobilization: reproductive rights organizations in the United States, 1920–1985
Authors: Hightower Tristan M. 
Published: January 2024

AbstractThis research note builds upon a number of important articles published in a variety of outlets concerning the population ecology of interest groups. Importantly, Lowery and Gray (1995), Nownes (2004), and Nownes and Lipinski (2005) empirically demonstrated the dependence on the density of pre-existing, similar groups when predicting new group formations. In this letter, I add to this research by modeling the density of ideologically divergent reproductive rights groups as well as offer supporting evidence for the popularEnergy-Stability-Areamodel. The former is a novel consideration in the field of population ecology which primarily examines ideologically similar groups. I show that density dependence is at play among these polarized groups. I also provide insight into counter-mobilization movements of group formation by empirically demonstrating which groups are initial movers versus reactionary formers. In doing so, I raise important questions for researchers concerned with the emergence, longevity, and impact of interest groups over long periods of time. Finally, this research provides some insight into the expectations of group formation behavior in light of the landmarkDobbsdecision.
New species ofDermoergasilusHo & Do, 1982 (Copepoda: Cyclopoida: Ergasilidae) parasitizing endemic cichlidParetroplus polyactis(Bleeker) in Madagascar
Authors: Míč Robert , Řehulková Eva , Šimková Andrea , Razanabolana Jeanne Rasamy , Seifertová Mária 
Published: January 2024

AbstractDermoergasilus madagascarensisn. sp. is described from the gills ofParetroplus polyactis, an endemic cichlid fish in Madagascar, using a combined morphological (light microscopy and SEM) and molecular approach (partial 18S rDNA, 28S rDNA, and COI sequences). The new species is characterized mainly by possessing: (i) roughly pentagonal cephalosome; (ii) antennal endopodal segments covered with slightly inflated membrane; (iii) maxillule bearing 2 equally long outer setae and a minute inner seta; (iv) interpodal sternites of swimming legs ornamented with 3–4 rows of spinules; (v) genital segment and first abdominal somite both barrel-shaped; and (vi) a caudal ramus projecting into a digitiform process with inconspicuous terminal seta and bearing 3 terminal setae. The obtained DNA sequences of Malagasy species represent the first molecular data for species ofDermoergasilus. The 28S rDNA phylogeny showed the affiliation ofD. madagascarensisn. sp. to Ergasilidae and its sister relationship with cosmopolitanErgasilus sieboldivon Nordmann, 1832. The first checklist for all species ofDermoergasilusis provided.
Collaring nature: The use of foxes to find and rescue the members of the lost Franklin expedition
Authors: Peck Robert M. 
Published: January 2024

AbstractThe mysterious disappearance ofHMS ErebusandHMS Terrorwhile searching for the Northwest Passage under the leadership of Sir John Franklin in the 1840s led to more than thirty different expeditions seeking to find the lost ships and their 129-man crews. It also fostered the first and only use of wild animals as a means of communication in such a rescue operation. Since covering the vast search areas was challenging, if not impossible during sub-freezing winter conditions, some of the would-be rescuers turned to Arctic foxes as couriers of information that they hoped might direct the lost explorers to safety. Based on excerpts from the participants’ diaries and published reports from the period, and on the physical evidence that survives, this paper describes the role Arctic foxes were asked to play in one of the greatest (unsuccessful) rescue efforts ever undertaken in the Far North.