bluuebunny/crossref_metadata_2025_split huggingface dataset:
Socio-economic Profiles of Maize Growers in Surguja District, Chhattisgarh, India
Authors: Priyanka Panna , P. K. Jaiswal , P. K. Pandey 
Published: January 2025

The present study was carried out in the Surguja district of Chhattisgarh state. Data were collected from 120 respondents from 8 selected villages. The results indicate that most of the respondents belonged to the middle age group, had a tribal category, had different level of education from primary to higher education level, were small size and had a joint family system, engaged in agriculture with labour activity, had an annual income and also the contribution of maize to their annual income was medium level, medium category of land ownership and large category of area under the maize cultivation, maize was the main commercial crop in wet and dry seasons, productivity of maize was medium level, low experience in cultivation, the majority of respondents consumed maize as flour/ bread, corn and animal/poultry feed, maximum respondents belonged in two or more organizations membership with moderate participation, Progressive farmers, Krishi Sangwari and RAEOs were major sources of technology information, tube wells were main source of irrigation, medium to a high level of knowledge of maize cultivation, regular available agricultural inputs, produce sold to local/outside traders, every respondents adopted the marketing channel as Producer-traders-wholesaler-retailer- consumer for their grain produce and did not adopt storage practice. The association of family size, occupation, annual income, land ownership, maize acreage, productivity, farming experience, knowledge of maize technology, marketing, education and source of irrigation were found positive and significantly correlated with the extent of adoption of maize technology. And remaining variables like the contribution of maize to their annual income, consumption pattern, social participation, extension agency contact, inputs availability and Storage practices were found nonsignificant association.
Probiotic Products: Appropriate Technologies for Control of Infectious Animal Diseases in the Face of Climate Change and Antimicrobial Resistance
Authors: Masola Seleman Nasib 
Published: January 2025

Probiotic products are products which contain probiotics; these are live non-pathogenic microorganisms which provide health benefits to the host when administered in adequate amounts. Currently the world is facing a climate change crisis which among other things, leads to alteration of the abundance, distribution and transmission of animal pathogens leading to increased incidences of animal diseases. Moreover, the world is facing a crisis of development of antimicrobial resistance (AMR) by many strains of pathogenic microorganisms. For many decades conventional technologies which have been used for control of infectious diseases in animals include vaccines, antimicrobials, acaricides, and antihelmintics. The AMR crisis has made antimicrobials not to be a reliable technology for control of some infectious diseases caused by pathogenic microorganisms. In attempts to look for alternative technologies other than vaccines, acaricides, and antihelmintics for control of infectious diseases in animals, many studies have been conducted to determine prophylactic efficacy of many strains of probiotics against the diseases. The objective of this paper is to review prophylactic efficacy of probiotic products against infectious animal diseases and provide insights on mechanisms of action of probiotics. Reports of prophylactic efficacy of probiotic products against animal diseases, and mechanisms of action of probiotics were searched using google search engine. After assessment of the reports; appropriate ones were selected, summarized, and globally synthesized. Many reports reporting significant prophylactic efficacy of probiotic products against infectious animal diseases were found. However, most studies focused on bacterial diseases of the digestive system. More studies focusing on bacterial, viral, and protozoal diseases of the digestive and other body systems of animals are recommended in order to get more data on the spectrum of activity of probiotics. Based on this review it is concluded that probiotic products have significant prophylactic efficacy against infectious animal diseases. The products are appropriate for use as alternative technologies to antimicrobials for control of infectious animal diseases in the AMR crisis. They are also appropriate for use in climate adapted livestock farming because apart from contributing to enhancement of animal health and productivity, they contribute to adaptation of some of the impacts of climate change in livestock farming (particularly increased incidences of animal diseases) by enhancing the resilience of livestock to diseases; and climate change mitigation by decreasing greenhouse gas intensity through enhanced animal health.
Stimuli‐Responsive 3D Printable Conductive Hydrogel: A Step toward Regulating Macrophage Polarization and Wound Healing
Authors: Lee Jieun , Dutta Sayan Deb , Acharya Rumi , Park Hyeonseo , Kim Hojin , Randhawa Aayushi , Patil Tejal V. , Ganguly Keya , Luthfikasari Rachmi , Lim Ki‐Taek 
Published: November 2023

AbstractConductive hydrogels (CHs) are promising alternatives for electrical stimulation of cells and tissues in biomedical engineering. Wound healing and immunomodulation are complex processes that involve multiple cell types and signaling pathways. 3D printable conductive hydrogels have emerged as an innovative approach to promote wound healing and modulate immune responses. CHs can facilitate electrical and mechanical stimuli, which can be beneficial for altering cellular metabolism and enhancing the efficiency of the delivery of therapeutic molecules. This review summarizes the recent advances in 3D printable conductive hydrogels for wound healing and their effect on macrophage polarization. This report also discusses the properties of various conductive materials that can be used to fabricate hydrogels to stimulate immune responses. Furthermore, this review highlights the challenges and limitations of using 3D printable CHs for future material discovery. Overall, 3D printable conductive hydrogels hold excellent potential for accelerating wound healing and immune responses, which can lead to the development of new therapeutic strategies for skin and immune‐related diseases.
Precipitated Iodine Cathode Enabled by Trifluoromethanesulfonate Oxidation for Cathode/Electrolyte Mutualistic Aqueous Zn–I Batteries
Authors: Zhang Kaiqiang , Yu Qianchuan , Sun Jingjie , Tie Zuoxiu , Jin Zhong 
Published: November 2023

AbstractAqueous Zn–I batteries hold great potential for high‐safety and sustainable energy storage. However, the iodide shuttling effect and the hydrogen evolution reaction that occur in the aqueous electrolyte remain the main obstacles for their further development. Herein, the design of a cathode/electrolyte mutualistic aqueous (CEMA) Zn–I battery based on the inherent oxidation ability of aqueous trifluoromethanesulfonate ((OTf)−) electrolyte toward triiodide species is presented. This results in the formation of iodine sediment particles assembled by fine iodine nanocrystals (≈10 nm). An iodine host cathode with high areal iodine loading is realized via a spontaneous absorption process that enriched redox‐active iodine and iodide species from aqueous electrolyte onto nanoporous carbon based current collector. By tuning iodide redox process and suppressing competitive hydrogen evolution reaction, the assembled CEMA Zn–I batteries demonstrate a remarkable capacity retention of 76.9% over 1000 cycles at 0.5 mA cm−2. Moreover, they exhibit a notable rate capability, with a capacity retention of 74.6% when the current density is increased from 0.5 to 5.0 mA cm−2. This study demonstrates the feasibility of using the oxidation effect to repel redox‐active species from the electrolyte to the cathode, paving a new avenue for high‐performance aqueous Zn–I batteries.
Transport Barriers Influence the Activation of Anti‐Tumor Immunity: A Systems Biology Analysis
Authors: Nikmaneshi Mohammad R. , Baish James W. , Zhou Hengbo , Padera Timothy P. , Munn Lance L. 
Published: November 2023

AbstractEffective anti‐cancer immune responses require activation of one or more naïve T cells. If the correct naïve T cell encounters its cognate antigen presented by an antigen presenting cell, then the T cell can activate and proliferate. Here, mathematical modeling is used to explore the possibility that immune activation in lymph nodes is a rate‐limiting step in anti‐cancer immunity and can affect response rates to immune checkpoint therapy. The model provides a mechanistic framework for optimizing cancer immunotherapy and developing testable solutions to unleash anti‐tumor immune responses for more patients with cancer. The results show that antigen production rate and trafficking of naïve T cells into the lymph nodes are key parameters and that treatments designed to enhance tumor antigen production can improve immune checkpoint therapies. The model underscores the potential of radiation therapy in augmenting tumor immunogenicity and neoantigen production for improved ICB therapy, while emphasizing the need for careful consideration in cases where antigen levels are already sufficient to avoid compromising the immune response.
Recent Progresses of Polarons: Fundamentals and Roles in Photocatalysis and Photoelectrocatalysis
Authors: Ren Zhizhen , Shi Zhijian , Feng Haifeng , Xu Zhongfei , Hao Weichang 
Published: November 2023

AbstractPhotocatalysis and photoelectrocatalysis are promising ways in the utilization of solar energy. To address the low efficiency of photocatalysts and photoelectrodes, in‐depth understanding of their catalytic mechanism is in urgent need. Recently, polaron is considered as an influential factor in catalysis, which brings researchers a new approach to modify photocatalysts and photoelectrodes. In this review, brief introduction of polaron is given first, followed by which models and recent experimentally observations of polarons are reviewed. Studies about roles of polarons in photocatalysis and photoelectrocatalysis are listed in order to provide some inspiration in exploring the mechanism and improving the efficiency of photocatalysis and photoelectrocatalysis.
Smart Aqueous Zinc Ion Battery: Operation Principles and Design Strategy
Authors: Zhang Xiaosheng , Jia Caoer , Zhang Jinyu , Zhang Linlin , Liu Xuying 
Published: November 2023

AbstractThe zinc ion battery (ZIB) as a promising energy storage device has attracted great attention due to its high safety, low cost, high capacity, and the integrated smart functions. Herein, the working principles of smart responses, smart self‐charging, smart electrochromic as well as smart integration of the battery are summarized. Thus, this review enables to inspire researchers to design the novel functional battery devices for extending their application prospects. In addition, the critical factors associated with the performance of the smart ZIBs are comprehensively collected and discussed from the viewpoint of the intellectualized design. A profound understanding for correlating the design philosophy in cathode materials and electrolytes with the electrode interface is provided. To address the current challenging issues and the development of smart ZIB systems, a wide variety of emerging strategies regarding the integrated battery system is finally prospected.
Breaking Mass Transport Limitations by Iodized Polyacrylonitrile Anodes for Extremely Fast‐Charging Lithium‐Ion Batteries
Authors: Ma Shaobo , Zhao Jingteng , Gao Qixin , Song Congying , Xiao Huang , Li Fang , Li Guoxing 
Published: November 2023

AbstractThe fast‐charging capability of rechargeable batteries is greatly limited by the sluggish ion transport kinetics in anode materials. Here we develop an iodized polyacrylonitrile (I‐PAN) anode that can boost the bulk/interphase lithium (Li)‐ion diffusion kinetics and accelerate Li‐ion desolvation process to realize high‐performance fast‐charging Li‐ion batteries. The iodine immobilized in I‐PAN framework expands ion transport channels, compresses the electric double layer, and changes the inner Helmholtz plane to form LiF/LiI‐rich solid electrolyte interphase layer. The dissolved iodine ions in the electrolyte self‐induced by the interfacial nucleophilic substitution of PF6− not only promote the Li‐ion desolvation process, but also reuse the plated/dead Li formed on the anode under fast‐charging conditions. Consequently, the I‐PAN anode exhibits a high capacity of 228.5 mAh g−1 (39 % of capacity at 0.5 A g−1 delivered in 18 seconds) and negligible capacity decay for 10000 cycles at 20 A g−1. The I‐PAN||LiNi0.8Co0.1Mn0.1O2 full cell shows excellent fast‐charging performance with attractive capacities and negligible capacity decay for 1000 cycles at extremely high rates of 5 C and 10 C (1 C=180 mA g−1). We also demonstrate high‐performance fast‐charging sodium‐ion batteries using I‐PAN anodes.
Subclinical epileptiform activity and sleep disturbances in Alzheimer's disease
Authors: Devulder Astrid , Macea Jaiver , Kalkanis Alexandros , De Winter François‐Laurent , Vandenbulcke Mathieu , Vandenberghe Rik , Testelmans Dries , Van Den Bossche Maarten J. A. , Van Paesschen Wim 
Published: November 2023

ABSTRACTIntroductionSubclinical epileptiform activity (SEA) and sleep disturbances are frequent in Alzheimer's disease (AD). Both have an important relation to cognition and potential therapeutic implications. We aimed to study a possible relationship between SEA and sleep disturbances in AD.MethodsIn this cross‐sectional study, we performed a 24‐h ambulatory EEG and polysomnography in 48 AD patients without diagnosis of epilepsy and 34 control subjects.ResultsSEA, mainly detected in frontotemporal brain regions during N2 with a median of three spikes/night [IQR1–17], was three times more prevalent in AD. AD patients had lower sleep efficacy, longer wake after sleep onset, more awakenings, more N1%, less REM sleep and a higher apnea‐hypopnea index (AHI) and oxygen desaturation index (ODI). Sleep was not different between AD subgroup with SEA (AD‐Epi+) and without SEA (AD‐Epi–); however, compared to controls, REM% was decreased and AHI and ODI were increased in the AD‐Epi+ subgroup.DiscussionDecreased REM sleep and more severe sleep‐disordered breathing might be related to SEA in AD. These results could have diagnostic and therapeutic implications and warrant further study at the intersection between sleep and epileptiform activity in AD.
Unlocking circular start‐ups: A model of barriers
Authors: Kasana Swati , Chavan Meena , Sedera Darshana , Cheng Zhiming , Ganzin Max 
Published: November 2023

AbstractThe concept of circular economy (CE) has emerged as a viable way to achieving sustainable development. Small businesses and start‐ups play a significant role in economic progress, but they also contribute substantially to environmental degradation. In this inductive qualitative study, we conducted multiple interviews with 18 founders of circular start‐ups (CSUs) in Australia to explore and understand the challenges they encountered at different stages of their development and growth. Employing grounded theory, this study unveils barriers associated with distinct phases of the CSU development and growth, categorizing them into antecedent, beginner and growth barriers. The empirical analysis paints a detailed picture of both unique and common obstacles related to the distinctive and novel positioning of CSUs in promoting CE. This research also serves as a valuable foundation for aspiring CE entrepreneurs, practitioners, scholars and policymakers.
Travels with tau prions
Authors: Diamond Marc I. 
Published: November 2023

AbstractTau was originally identified as a microtubule associated protein, and subsequently recognized to constitute the fibrillar assemblies found in Alzheimer disease and related neurodegenerative tauopathies. Point mutations in the microtubule associated protein tau (MAPT) gene cause dominantly inherited tauopathies, and most predispose it to aggregate. This indicates tau aggregation underlies pathogenesis of tauopathies. Our work has suggested that tau functions as a prion, forming unique intracellular pathological assemblies that subsequently move to other cells, inducing further aggregation that underlies disease progression. Remarkably, in simple cells tau forms stably propagating aggregates of distinct conformation, termed strains. Each strain induces a unique and, in some cases, transmissible, neuropathological phenotype upon inoculation into a mouse model. After binding heparan sulfate proteoglycans on the plasma membrane, tau assemblies enter cells via macropinocytosis. From within a vesicle, if not trafficked to the endolysosomal system, tau subsequently enters the cytoplasm, where it becomes a template for its own replication, apparently after processing by valosin containing protein. The smallest seed unit is a stable monomer, which suggests that initial folding events in tau presage subsequent pathological aggregation. The study of tau prions has raised important questions about basic cell biological processes that underlie their replication and propagation, with implications for therapy of tauopathies.
Landscape‐wide pulse events predict trait‐based responses among wetland birds in perennial channels of a dryland wetland
Authors: Becker Frowin K. , Boyes Rutledge S. , Wittmer Heiko U. , Inman Victoria , Marsland Stephen 
Published: November 2023

AbstractWetlands in arid or semiarid zones are vital for maintaining biodiversity but face growing threats. Flooding regime variability is a key driver of ecological dynamism in these systems, dictating primary productivity on a large spatial scale. The functional composition or diversity of wetland‐dependent bird species has been found to be sensitive to fluctuations in hydrological regimes and can thus be indicative of cascading ecosystem responses associated with climate change. In this paper, we investigate whether large‐scale changes in inundation and fire—a significant additional biodiversity determinant in (semi‐)arid landscapes—are reliable predictors of functional group responses of wetland‐dependent birds along a perennial channel of the Okavango Delta, Botswana. We fit generalized additive models (GAMs) to 6 years of bird survey data collected along ~190‐km‐long annual transects and use remotely sensed landscape‐level inundation estimates, as well as spatiotemporal distance to fire, to predict the responsiveness of seven trait‐based functional group abundances. During the surveys, a total of 89 different wetland‐dependent bird species were recorded, including 76 residents, across all years, with below‐surface feeding waders consistently the most abundant functional group. Including estimated spatiotemporal variability in flooding and fire, as well as their interactions, improved model fit for all seven functional groups, explaining between 46.8% and 68.3% of variability in functional group abundances. Covariates representing longer‐term variability in inundation generally performed better than shorter‐term ones. For example, variability in inundation over the 5 months preceding a survey best predicted the responses of all functional groups, which also all exhibited responsiveness to the interaction between flooding and fire. We were able to interpret the responses of individual functional groups, based on the resource exploitation assumption. Overall, our results suggest that perennial waters in dryland wetlands offer functional refugia to wetland‐dependent birds and highlight the indicative power of large‐scale trait‐based bird monitoring. Our findings demonstrate the potential utility of such a monitoring regime for dryland wetland ecosystems vulnerable to industrial‐scale anthropogenic pressure and associated climate change.
Intramuscular injections of botulinum toxin for the treatment of upper back myofascial pain syndrome: A systematic review of randomized controlled trials
Authors: Leonardi G. , Alito A. , Portaro S. , Di Matteo B. , Respizzi S. , Kon E. , Massazza G. , Sconza C. 
Published: November 2023

AbstractBackground and ObjectiveMyofascial pain syndrome (MPS) is a chronic musculoskeletal disorder characterized by the presence of trigger points. Among the treatment options, botulinum toxin injections have been investigated. The aim of this paper was to provide a synthesis of the evidence on intramuscular botulinum toxin injections for upper back MPS.Databases and Data TreatmentA systematic review of the literature was performed on the PubMed, Scopus and Cochrane Library, using the following formula: (“botulinum”) AND (“musculoskeletal”) AND (“upper back pain”) OR (“myofascial pain”).ResultsTen studies involving 651 patients were included. Patients in the control groups received placebo (saline solution) injections, anaesthetic injections + dry needling or anaesthetic injections. The analysis of the trials revealed modest methodological quality: one “Good quality” study, one “Fair” and the other “Poor”. No major complications or serious adverse events were reported. Results provided conflicting evidence and did not demonstrate the superiority of botulinum toxin over comparators. Most of the included trials were characterized by a small sample size, weak power analysis, different clinical scores used and non‐comparable follow‐up periods. Even if there is no conclusive evidence, the favourable safety profile and the positive results of some secondary endpoints suggest a potentially beneficial action in pain control and quality of life.ConclusionThe currently available studies show conflicting results. Their overall low methodological quality does not allow for solid evidence of superiority over other comparison treatments. Further insights are needed to properly profile patients who could benefit more from this peculiar injective approach.SignificanceThe randomized controlled trials included in this review compared using botulinum toxin to treat upper back MPS with placebo or active treatments (e.g., dry needling or anaesthetics) showing mixed results overall. Despite the lack of clear evidence of superiority, our study suggests that the use of botulinum toxin should not be discouraged. Its safety profile and encouraging results in pain control, motor recovery and disability reduction make it an interesting treatment, particularly in the subset of patients with moderate to severe chronic pain and active trigger points. To support the safety and efficacy of botulinum toxin, further high‐quality studies are needed.
Locally correlated Poisson sampling
Authors: Prentius Wilmer 
Published: November 2023

AbstractDesigns that produces spatially balanced, or well‐spread, samples are desirable as they increase the probability of obtaining a sample highly representative of the population. Spatially correlated Poisson sampling (SCPS) is a method for selecting well‐spread samples. In the SCPS method, the sampling outcomes (inclusion or exclusion of units) are decided sequentially. After each decision, the inclusion probabilities of surrounding units are updated. A specific order for deciding the sampling outcomes is not enforced for SCPS, that is, the order can be chosen randomly or be fixed. A new modified method called locally correlated Poisson sampling (LCPS) is suggested. In this new method, the order of the decisions makes sure the inclusion probabilities are updated (more) locally. As a result, a stronger negative correlation between inclusion indicators of nearby units is achieved. Simulations on various data sets show that the resulting samples from LCPS, in general, are more spatially balanced and produce lower variance than samples from SCPS and the local pivotal method.