bluuebunny/crossref_metadata_2025_split huggingface dataset:
PENGARUH POLA PENGERINGAN TERHADAP RENDEMEN DAN KUALITAS MINYAK ATSIRI DAUN NILAM (Pogostemon calbin Benth)
Authors: Chotimah Husnul , Yanuar Vita , Noor Sikin M 
Published: October 2023

The nilam plant (Pogostemon Calbin Benth) is a type of plant that has fibrous roots that can live in upland and lowland areas. Nilam will grow well at an altitude of 10 to 400 meters above sea level. The spread of patchouli in South Kalimantan covers the Bati-Bati District and Pelaihari Regency. Nilam (Pogostemon Calbin Benth) contains patchouli alcohol which is used as a binder for fragrance ingredients. This study aims to determine the yield and quality of essential oil from nilam (Pogostemon Calbin Benth) using water and steam distillation methods in various leaf drying patterns. This research was initiated by drying the material and then distilling it to obtain essential oils. Laboratory tests for the content of chemical compounds were carried out at the Agricultural Research and Development Center, Research Institute for Medicinal and Aromatic Plants Bogor to determine the levels of cineol and patchouli alcohol. Laboratory tests showed the highest cineol content in fresh material (77.4%) and the highest patchouli alcohol in sun-dried material (22.95%). Tumbuhan nilam (Pogostemon Calbin Benth) merupakan jenis tanaman yang memiliki akar serabut yang dapat hidup di daerah dataran tinggi dan rendah. Nilam akan tumbuh baik pada ketinggian 10 sampai 400 meter di permukaan laut. Penyebaran nilam di Kalimantan Selatan meliputi wilayah Kecamatan Bati-Bati dan Kabupaten Pelaihari. Nilam (Pogostemon Calbin Benth) memiliki kandungan patchouli alkohol yang digunakan sebagai pengikat bahan-bahan pewangi. Penelitian ini bertujuan mengetahui rendemen dan kualitas minyak atsiri dari tumbuhan Nilam (Pogostemon Calbin Benth) dengan metode penyulingan air dan uap (water and steam destillation) dalam berbagai pola pengeringan daun. Penelitian ini diawali dengan melakukan pengeringan bahan kemudian penyulingan untuk memperoleh minyak atsiri. Uji Laboratorium kandungan senyawa kimia dilakukan di Balai Penelitian dan Pengembangan Pertanian, Balai Penelitian Tanaman Obat dan Aromatika Bogor untuk mengetahui kadar sineol dan Patchouli alkohol. Menunjukkan hasil kadar sineol tertinggi pada bahan segar (77,4%) dan patchouli alkohol tertinggi pada bahan kering matahari (22,95%).
SIFAT FISIK BIODEGRADABLE POT (BIOPOT) DARI TANDAN KOSONG KELAPA SAWIT (Elaeis gueneensis), ECENG GONDOK (Eichhornia crassipes), GAMAL (Gliricidia maculata), PUPUK ORGANIK DAN PEREKAT TAPIOKA
Authors: Indrianti Endras , Rahmadi Adi , Thamrin Gusti Abdul Rahmat 
Published: October 2023

The amount and type of plastic waste type in each country. Indonesia’s waste according to the Ministry of Environment and Forestry is 175,000 tons/day including 15% plastic waste. Nursery activities in the forestry and plantation sectors in providing mass seedlings still use plastic-based polybags. The purpose of this study was to analyze the physical properties of biodegradable pots (biopots) from oil palm empty bunches, hyacinth, gamal leaf, organic fertilizers and tapioca adhesives. The research method used was a Complete Randomized Design (RAL) with 3 treatments with 3 repeats so that the number of samples was 9 biodegradable pots. The test results of the physical properties of the biodegradable pot obtained are water content tests ranging from 9.85%-11.41%, the range of water absorption test values ranges from 136.42%-147.87%.The best treatment for the biodegradable pot water content test was found in the P3 treatment the lowest water content of 9.85% and the highest water absorption of 147.87%.Sampah plastik yang jumlah dan jenis berbeda-beda di setiap negara. Negara Indonesia menurut data kementrian KLHK 175.000 ton/hari termasuk sampah plastik 15%. Kegiatan persemaian dalam sektor kehutanan maupun perkebunan dalam penyediaan bibit massal masih menggunakan polybag yang berbahan dasar plastik. Tujuan dari penelitian ini adalah menganalisis sifat fisik biodegradable pot dari tandan kosong kelapa sawit, eceng gondok, daun gamal, pupuk organik dan perekat tapioka. Metode penelitian yang digunakan adalah Rancangan Acak Lengkap (RAL) dengan 3 kali perlakuan dengan 3 kali ulangan sehingga jumlah sampel 9 biopot. Hasil pengujian sifat fisik biopot yang diperoleh yaitu uji kadar air berkisar antara 9,85%-11,41%, kisaran nilai uji daya serap air berkisar antara 136,42%-147,87%. Perlakuan terbaik uji kadar air biopot terdapat pada perlakuan P3 dengan kadar air terendah 9,85% dan daya serap air tertinggi 147,87%
PERBANDINGAN BIAYA DAN PENDAPATAN POLA AGROFORESTRI DARI ANGGOTA DAN BUKAN ANGGOTA KUPS AGROFORESTRI DI DESA NALUI KECAMATAN JARO
Authors: Safitri Hariyati , Itta Daniel , Asysyifa Asysyifa 
Published: October 2023

This study aims to analyze income cost and benefit of agroforestry patterns from member and non-members Social Forestry Business Group (SFBG) in Nalui Village, Jaro Distric. This research was conducted in Nalui Village, Jaro District by taking a sensus sample of 13 SFBG members and 15 respondentswho ware not SFBG members using a quantitativemethode based on a structure list of question (questuonnaires). The largest costcomparison is found inrespondents who are not SFBG member of Rp.4.715,361.00/year, the largest income and profit is found in agroforestry SFBG members, which are Rp. 17.731.795,00/year and Rp.22.447.157.00Penelitian ini bertujuan menganalisis biaya pendpataan dan keuntungan pola agroforestri dari anggota dan bukan anggota Kelompok Usaha Perhutanan Sosial (KUPS) agroforestri di Desa Nalui Kecamatan Jaro. Penelitian ini dilakasanakan di Desa Nalui Kecamatan Jaro dengan pengambilan sampel secara sensus 13 anggota KUPS dan secara sengaja 15 reponden bukan anggota KUPS menggunakan metode kuantitatif berdasarkan daftar pertanyaan terstruktur (kuesioner). Perbandingan biaya terbesar terdapat pada responden bukan anggota KUPS sebesar Rp.4.715.361,00/tahun, perbandingan pendapatan dan keuntungan terbesar terdapat pada anggota KUPS agroforestri yaitu sebesar Rp.17.731.795,00/tahun dan Rp.22.447.157,00
CHARACTERIZATION OF CORN STARCH EDIBLE FILMS BY THE ADDITION OF CHITOSAN AS A VEGETABLE OIL PACKAGING MATERIAL
Authors: Wicakso Doni Rahmat , Fortuna Dwi , Hernadin Ivan Aldino 
Published: October 2023

Abstract - Vegetable oil packaging materials use a type of synthetic polymer that is harmful to the body and the environment. Edible film as an environmentally friendly packaging material can be a solution for vegetable oil packaging material. Edible films are made from natural ingredients such as starch and chitosan. The objective of this study is to determine the best conditions of addition of chitosan in making edible film in terms of its physio-chemicals and determine the best glycerol concentration in terms of its physical properties. The composition of raw materials in the form of corn starch is 5 grams and the composition of chitosan is (0,5%, 1% and 1,5% b/v). Glycerol concentrations vary in (4%, 5% and 6% v/v). the result of the analysis of the physical properties of the edible film through the analysis of the physical tensile strength test, namely the best composition on the addition of 1 gr chitosan as well as the elongation analysis at termination. Analysis of the solubility of the edible film at a concentration of 1 gr as well the analysis of water vapor permeability. Whereas the analysis of the best antioxidant capacity in the composition of chitosan is 1,5 gr. Keywords: corn starch, chitosan, edible film
ANALISIS METODE PENERJEMAHAN DESKRIPSI LATAR BELAKANG HERO CADIA RIVERLANDS DAN VONETIS ISLANDS DALAM GAME MOBILE LEGENDS
Authors: Margono Livia Dwi Oktavianti , Delijar Ressi Maulidina 
Published: October 2023

Saat ini game banyak diminati oleh berbagai kalangan orang, mulai dari anak kecil hingga orang dewasa. Dalam game banyak karakter atau hero yang menarik dan bisa dimainkan, salah satunya adalah game mobile legends. Mobile legends merupakan game online asal Cina yang digemari oleh pemain dari berbagai negara salah satunya Indonesia. Game ini digemari karena memiliki banyak hero dengan kemampuan khusus yang memiliki latar belakang menarik. Penelitian ini membahas analisis metode penerjemahan yang digunakan dalam latar belakang hero Cadia Riverlands dan Vonetis Islands dalam game Mobile Legends. Jenis penilitian yang digunakan yaitu penelitian kualitatif dengan metode penelitian analisis deskriptif. Metode pengumpulan data menggunakan metode catat hasil pengamatan.Teori yang digunakan untuk menganalisis adalah teori metode penerjemahan Newmark (1988). Hasil dari data yang dianalisis ditemukan 25 hero Mobile Legends, 14 hero Cadia Riverlands, dan 11 hero Vonetis Islands. Dari 8 metode penerjemahan, pada latar belakang hero Cadia Riverlands dan Vonetis Islands dalam Mobile Legends hanya ditemukan 2 metode penerjemahan yang digunakan yaitu, 18 kalimat menggunakan metode penerjemahan bebas dan 7 kalimat menggunakan metode penerjemahan komunikatif.
Kata Kunci : metode penerjemahan, deskripsi, game, Mobile Legends.
Coping Strategies in Clinical Psychology and Neuropsychology
Authors: Theodoratou Maria 
Published: October 2023

The primary focus of this review is to explore the application and significance of coping strategies within the domains of clinical psychology and neuropsychology. These strategies consist of a variety of techniques, behaviors, and cognitive interventions, and their critical role in reinforcing resilience and facilitating adaptive responses to stressors has been highlighted. At the core of this exploration, the intricate neuropsychological relationship between brain stress pathways and the application of coping mechanisms has been analyzed. The neural aspects of stress, and how they can be influenced by adaptive strategies, are detailed, illustrating the profound impact these coping mechanisms have at a neurobiological level.
Delving into the neuropsychological underpinnings, this review will shed light on how stress response pathways in the brain interact with, and can be modulated by, various coping strategies. These mechanisms are particularly salient when addressing the multifaceted challenges faced by individuals with neuropsychological or mental health issues. While these strategies span a broad spectrum, from introspection and cognitive reframing to behavioral activation and social support seeking, their integration and application remain diverse within clinical contexts. This review endeavors to elucidate the theoretical underpinnings of these strategies, their empirical support, and their practical implications within therapeutic interventions. Furthermore, the intricate interplay between individualized coping techniques and structured therapeutic methodologies will be examined, emphasizing the potential for a holistic treatment paradigm, thereby enhancing therapeutic outcomes and fostering individual resilience.
Attosecond dynamics of photoemission over a wide photon energy range
Authors: Schröder Christian , Riemensberger Johann , Kuzian Roman , Ossiander Marcus , Potamianos Dyonisios , Allegrett Francesco , Bignardi Luca , Lizzit Silvano , Akil Ayman , Cavalieri Adrian , Menzel Dietrich , Neppl Stefan , Ernstorfer Raph , Braun Jürgen , Ebert Hubert , Minar Jan , Helml Wolfram , Jobst Michael , Gerl Michael , Bothschafter Elisabeth , Kim Andreas , Hütten Konrad , Kleineberg Ulf , Schnitzenbaumer Maximilian , Barth Johannes , Feulner Peter , Krasovskii Eugene , Kienberger Reinhard 
Published: October 2023

Abstract
Dynamics of photoemission from surfaces are usually studied at low photon energies (<100 eV). Here, we report on new findings on these dynamics observed at a tungsten surface on the attosecond time scale at photon energies exceeding 100 eV, over a range of almost 50 eV.
While photoemission, a fundamental process in quantum mechanics, is often described within a semiclassical three-step model, we find that even at high photon energies only a full quantum treatment in one step predicts the measured attosecond dynamics correctly. On this time scale the intuitive, mechanistic interpretation of the photoelectric effect breaks down. This underlines the necessity to further develop experimental and theoretical tools to be used in improving our understanding of the fundamental process of light-matter interaction underlying many methods in extreme ultraviolet and soft x-ray spectroscopy.
Optimizing livestock farm size to reduce nitrogen loss in China
Authors: Gu Baojing , Cheng Luxi , Zhang Xiuming , Zhu Zhiping , Wang Chen , Ren Chenchen , Reis Stefan 
Published: October 2023

Abstract

The size of livestock production in farming is an important factor influencing management strategies, and ultimately affects nitrogen use efficiency (NUE) and nitrogen emissions. Here, by using data from 390,000 farms covering four major livestock animal types across China in 2017, we investigate the relationship between the NUE, nitrogen losses and livestock farm size. Our results show that NUE increases with farm size for all livestock types, while nitrogen losses and manure recycling ratios vary between different livestock types, highlighting the need for tailored management strategies. By optimizing farm size through consolidation or splitting of farms for the specific livestock species at the county scale, while maintaining a constant level of feed supply, China would increase manure recycling to croplands by 6%, increase livestock production by 3% and reduce nitrogen losses by 259,000 tonnes (14%), which could bring notable benefits to environmental protection and food security.
KIF1C activates and extends dynein movement through the FHF cargo adaptor
Authors: Straube Anne , Ali Ferdos Abid , Zwetsloot Alexander , Stone Caroline , Morgan Tomos , Wademan Richard , Carter Andrew 
Published: October 2023

Abstract

Cellular cargos move bidirectionally on microtubules due to the presence of opposite polarity motors dynein and kinesin. Many studies show these motors are co-dependent, whereby one requires the activity of the other, although the mechanism is unknown. Here, using in vitro motility assays, we show that the kinesin-3 KIF1C acts both as an activator and a processivity factor for dynein. Activation only requires a fragment of the non-motor tail of KIF1C (KIF1C-stalk) to bind the cargo adaptor HOOK3. Cryo-EM, crosslinking mass spectrometry and AlphaFold2 predictions reveal this binding site to be separate from that of two constitutive factors (FTS and FHIP), which link HOOK3 to small G-proteins on cargos. We provide a structural model for how the FTS-HOOK3-FHIP1B (FHF) complex is auto-inhibited and explain how the KIF1C-stalk relieves this inhibition. Collectively, our work provides a molecular explanation for co-dependency by revealing that the mutual activation of dynein and kinesin is mediated through their shared adaptor. Many adaptors bind both dynein and kinesins, suggesting this mechanism could be generalised to other bidirectional complexes.
Combining degree centrality and betweenness centrality of molecular networks can effectively pinpoint individuals at high risk of HIV transmission within the network
Authors: Gan Wen , Zhao Bin , Song Wei , Kang Mingming , Dong Xue , Li Xin , Wang Lu , Liu Jianmin , Ding Haibo , Chu Zhenxing , Wang Lin , Tian Wen , Shang Hong , Han Xiaoxu 
Published: October 2023

Abstract

Background. HIV molecular network technology can identify HIV transmission hotspots and individuals at risk of HIV transmission, facilitating precise and targeted interventions. This study explored the molecular network parameters, namely degree centrality (DC) and betweenness centrality (BC), to effectively pinpoint individuals at high risk of HIV transmission within the network.
Methods. HIV pol gene and demographic and clinical information were collected from a whole-population sampling cohort comprising all newly diagnosed people living with HIV (PLWH) in Shenyang, from 2016 to 2019. Molecular networks were constructed, and three groups were identified based on DC and BC: high DC group (>the median DC), high BC group (>the mean BC), and high DC+BC group (both >the median DC and >the mean BC). The average risk of HIV transmission was calculated by dividing the total probability of recent HIV infections (identified by HIV-1 LAg-Avidity EIA) by the number of cases in each group. A multivariate logistic regression analysis was conducted to identify the characteristics of men who have sex with men (MSM) in the three groups.
Results. Of the 2882 PLWH, 1162 were included in the molecular network. The median DC and the mean BC of all nodes were 3 (range: 1-28) and 0.09 (range: 0-1), respectively. The average risk of HIV transmission was highest in the high DC+BC group (n=92) at 0.49, followed by the high BC group (n=201) at 0.37, and the high DC group (n=169) at 0.29. The characteristics of MSM with high DC+BC overlapped with those of MSM with high DC (low education levels, P=0.031) and MSM with high BC (unemployed, P=0.027 and high baseline viral load[≥105copies/mL], P=0.003).
Conclusion. The combined utilization of DC and BC can effectively identify individuals at high risk of HIV transmission, enabling precisely targeted interventions using molecular network technology.
Noncovalent Synthesis of Homo and Hetero-Architectures of Supramolecular Polymers via Secondary Nucleation
Authors: Kotagiri Venkata Rao , Kotha Srinu , Sahu Rahul , Yadav Aditya , Sharma Preeti , B.V.V.S Pavan , Reddy Sandeep 
Published: October 2023

Abstract

The synthesis of supramolecular polymers (SPs) with controlled architecture is a grand challenge in supramolecular chemistry. Although living supramolecular polymerization (LSP) via primary nucleation has been extensively studied for controlling the supramolecular polymerization of small molecules, the resulting SPs have typically exhibited one-dimensional (1D) morphology. In this report, we present the synthesis of intriguing SP architectures through a secondary nucleation event, a mechanism well-established in protein aggregation and the crystallization of small molecules. To achieve this, we selected perylene diimide with 2-ethylhexyl chains (2EH-PDI) at the imide position and stabilized its dormant monomers in solution. Activating these dormant monomers via mechanical stimuli (self-seeding) and hetero-seeding using propoxyethyl PDI (PE-PDI) seeds, secondary nucleation event takes over, leading to the formation of 3D spherical spherulites and scarf-like SP heterostructures, respectively. Therefore, the results presented in this study propose a simple molecular design for synthesizing well-defined SP architectures via secondary nucleation.
Causality between various cytokines and asthma: a bidirectional two-sample Mendelian randomization analysis
Authors: Zheng Yansen , Chen Qi , Shi Xiaqing , Lei Lei , Wang Donglin 
Published: October 2023

Abstract
Background
Many studies have shown that cytokines play an important role in the pathogenesis of asthma, but their biological effects on asthma remain unclear. Mendelian randomization (MR) method was used to evaluate the causal relationship between various cytokines (such as interleukins(ILs), interferons (IFNs), tumor necrosis factors (TNFs), colony-stimulating factors༈CSFs༉, transforming growth factor (TGF), etc.) and asthma.
Methods
In this study, inverse variance weighting was used to evaluate the causal relationship between asthma and cytokines. In addition, the reliability of the results is ensured by multiple methods such as MR-Egger, weighted median, MR-Raps, MR-Presso, and RadialMR, as well as sensitivity analysis.
Results
The results showed that none of the 11 cytokines was associated with the risk of asthma. In contrast, asthma can increase levels of IL-5 ( OR = 1.112, 95% CI 1.009–1.224, P = 0.032) and IL-9 ( OR = 1.111, 95% CI 1.013–1.219, P = 0.025).
Conclusions
Genetically predicted asthma was positively associated with elevated levels of IL-5 and IL-9. This indicates the downstream effects of IL-5 and IL-9 on asthma, and the design of treatments targeting IL-5 and IL-9 to prevent asthma exacerbations.
Novel putative causal mutations associated with fat traits in Nellore cattle uncovered by eQTLs located in open chromatin regions
Authors: Garcia Ingrid Soares , Silva-Vignato Bárbara , Cesar Aline Silva Mello , Petrini Juliana , Silva Vinicius Henrique da , Morosini Natália Silva , Goes Carolina Purcell , Afonso Juliana , Silva Thaís Ribeiro da , Lima Beatriz Delcarme , Clemente Luan Gaspar , Regitano Luciana Correia de Almeida , Mourão Gerson Barreto , Coutinho Luiz Lehmann 
Published: October 2023

Abstract

Intramuscular fat (IMF) and backfat thickness (BFT) are critical economic traits impacting meat quality. However, the genetic variants controlling these traits need to be better understood. To advance the knowledge in this area, we integrated RNA-seq and SNPs identified in genomic and transcriptomic data to generate a linkage disequilibrium filtered panel of 553,581 variants. eQTL analysis revealed 36,916 cis-eQTLs and 14,408 trans-eQTLs. Association analysis resulted in three eQTLs associated with BFT and 24 with IMF. Functional enrichment analysis of genes regulated by these 27 eQTLs revealed noteworthy pathways, such as immune response, cytoskeleton remodeling, iron transport, and phospholipid metabolism. These pathways can play a fundamental role in lipid metabolism and fat deposition. We next used ATAC-Seq assay to identify and overlap eQTL and open chromatin regions. Six eQTLs were in regulatory regions, four in predicted insulators and possible CCCTC-binding factor DNA binding sites, one in an active enhancer region, and the last in a low signal region. Our results provided novel insights into the transcriptional regulation of IMF and BFT, unraveling putative regulatory variants.
Oxidative damage and cell cycle delay induced by vanadium(III) in human cells
Authors: Alcántara-Mejía Víctor Alan , Rodríguez-Mercado Juan José , Mateos-Nava Rodrigo Aníbal , Álvarez-Barrera Lucila , Santiago-Osorio Edelmiro , Bonilla-González Edmundo , Altamirano-Lozano Mario Agustín 
Published: October 2023

Abstract
Vanadium (V) is a metal that can enter the environment through natural routes or anthropogenic activity. In the atmosphere, V is present as V oxides, among which vanadium(III) oxide (V2O3) stands out. Cytogenetic studies show that V2O3 is genotoxic and cytostatic and induces DNA damage; however, the molecular mechanisms leading to these effects have not been fully explored. Therefore, we used human peripheral blood lymphocytes treated in vitro and evaluated the effects of V2O3 on the phases of the cell cycle, the expression of molecules that control the cell cycle and detect DNA damage, and the induction of oxidative stress. The results reveal that V2O3 does not produce changes in cell viability at the concentrations (2, 4, 8 or 16 µg/mL) and exposure time (24 h) used. However, V2O3 modifies the percentage of G1 and S phase cells in the cell cycle, decreases the expression of mRNA in their respective proteins (cyclin D, cyclin E, cdk2 and cdk4) and increases the expression of γH2AX and the levels of reactive oxygen species. The ability of V2O3 to cause cell cycle delay in G1-S phase may be associated with a decrease in mRNA cyclin-cdk and its proteins and with intracellular oxidative stress, which may cause DNA double-strand damage and H2AX phosphorylation.