bluuebunny/crossref_metadata_2025_split huggingface dataset:
Ancient mural segmentation based on multiscale feature fusion and dual attention enhancement
Authors: Cao Jianfang , Cao Zhen , Chen Zhiqiang , Wang Fang , Wang Xianhui , Yang Zhuolin 
Published: February 2024

Abstract
To address the fuzzy segmentation boundaries, missing details, small target losses and low efficiency of traditional segmentation methods in ancient mural image segmentation scenarios, this paper proposes a mural segmentation model based on multiscale feature fusion and a dual attention-augmented segmentation model (MFAM). The model uses the MobileViT network, which integrates a coordinate attention mechanism, as the feature extraction backbone network. It attains global and local expression capabilities through self-attention, class convolution, and coordinate attention and focuses on location information to expand the receptive field and achieve improved feature extraction efficiency. An A_R_ASPP feature enhancement module is proposed for the attention-optimized residual atrous spatial pyramid pooling module. The module uses residual connections to solve the small target loss problem in murals caused by the excessive sampling rate of atrous convolution and uses a feature attention mechanism to adaptively adjust the feature map weight according to the channel importance levels. A dual attention-enhanced feature fusion module is proposed for multiscale decoder feature fusion to improve the mural segmentation effect. This module uses a cross-level aggregation strategy and an attention mechanism to weight the importance of different feature levels to obtain multilevel semantic feature representations. The model improves the mean intersection over union (MIoU) by 3.06% and the MPA by 1.81% on a mural dataset compared with other models. The model is proven to be effective at improving the segmentation details, efficiency and small target segmentation results produced for mural images, and a new method is proposed for segmenting ancient mural images.
Participatory translational science of neurodivergence: model for attention-deficit/hyperactivity disorder and autism research
Authors: Sonuga-Barke Edmund J.S. , Chandler Susie , Lukito Steve , Kakoulidou Myrofora , Moore Graham , Cooper Niki , Matejko Maciej , Jackson Isabel , Balwani Beta , Boyens Tiegan , Poulton Dorian , Harvey-Nguyen Luke , Baker Sylvan , Pavlopoulou Georgia 
Published: February 2024

BackgroundThere are increasing calls for neurodivergent peoples’ involvement in research into neurodevelopmental conditions. So far, however, this has tended to be achieved only through membership of external patient and public involvement (PPI) panels. The Regulating Emotions – Strengthening Adolescent Resilience (RE-STAR) programme is building a new participatory model of translational research that places young people with diagnoses of attention-deficit hyperactivity disorder (ADHD) and autism at the heart of the research team so that they can contribute to shaping and delivering its research plan.AimsTo outline the principles on which the RE-STAR participatory model is based and describe its practical implementation and benefits, especially concerning the central role of members of the Youth Researcher Panel (Y-RPers).MethodThe model presented is a culmination of a 24-month process during which Y-RPers moved from advisors to co-researchers integrated within RE-STAR. It is shaped by the principles of co-intentionality. The account here was agreed following multiple iterative cycles of collaborative discussion between academic researchers, Y-RPers and other stakeholders.ResultsBased on our collective reflections we offer general guidance on how to effectively integrate young people with diagnoses of ADHD and/or autism into the core of the translational research process. We also describe the specific theoretical, methodological and analytical benefits of Y-RPer involvement in RE-STAR.ConclusionsAlthough in its infancy, RE-STAR has demonstrated the model's potential to enrich translational science in a way that can change our understanding of the relationship between autism, ADHD and mental health. When appropriately adapted we believe the model can be applied to other types of neurodivergence and/or mental health conditions.
Association Between Neighborhood Opportunity, Allostatic Load, and All-Cause Mortality in Patients With Breast Cancer
Authors: Chen J.C. , Elsaid Mohamed I. , Handley Demond , Plascak Jesse J. , Andersen Barbara L. , Carson William E. , Pawlik Timothy M. , Fareed Naleef , Obeng-Gyasi Samilia 
Published: February 2024

PURPOSE Adverse neighborhood contextual factors may affect breast cancer outcomes through environmental, psychosocial, and biological pathways. The objective of this study is to examine the relationship between allostatic load (AL), neighborhood opportunity, and all-cause mortality among patients with breast cancer. METHODS Women age 18 years and older with newly diagnosed stage I-III breast cancer who received surgical treatment between January 1, 2012, and December 31, 2020, at a National Cancer Institute Comprehensive Cancer Center were identified. Neighborhood opportunity was operationalized using the 2014-2018 Ohio Opportunity Index (OOI), a composite measure derived from neighborhood level transportation, education, employment, health, housing, crime, and environment. Logistic and Cox regression models tested associations between the OOI, AL, and all-cause mortality. RESULTS The study cohort included 4,089 patients. Residence in neighborhoods with low OOI was associated with high AL (adjusted odds ratio, 1.21 [95% CI, 1.05 to 1.40]). On adjusted analysis, low OOI was associated with greater risk of all-cause mortality (adjusted hazard ratio [aHR], 1.45 [95% CI, 1.11 to 1.89]). Relative to the highest (99th percentile) level of opportunity, risk of all-cause mortality steeply increased up to the 70th percentile, at which point the rate of increase plateaued. There was no interaction between the composite OOI and AL on all-cause mortality ( P = .12). However, there was a higher mortality risk among patients with high AL residing in lower-opportunity environments (aHR, 1.96), but not in higher-opportunity environments (aHR, 1.02; P interaction = .02). CONCLUSION Lower neighborhood opportunity was associated with higher AL and greater risk of all-cause mortality among patients with breast cancer. Additionally, environmental factors and AL interacted to influence all-cause mortality. Future studies should focus on interventions at the neighborhood and individual level to address socioeconomically based disparities in breast cancer.
Romidepsin Plus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone Versus Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Patients With Previously Untreated Peripheral T-Cell Lymphoma: Final Analysis of the Ro-CHOP Trial
Authors: Camus Vincent , Thieblemont Catherine , Gaulard Philippe , Cheminant Morgane , Casasnovas Rene-Olivier , Ysebaert Loïc , Damaj Gandhi Laurent , Guidez Stéphanie , Pica Gian Matteo , Kim Won Seog , Lim Soon Thye , Andre Marc , Gutiérrez Norma , Penarrubia Maria Jesus , Staber Philipp B. , Trotman Judith , Hüttmann Andreas , Stefoni Vittorio , Tucci Alessandra , Fogarty Patrick , Farhat Hassan , Abraham Julie , Abarah Wajed , Belmecheri Fatiha , Ribrag Vincent , Delfau-Larue Marie-Helene , Cottereau Anne-Ségolène , Itti Emmanuel , Li Ju , Delarue Richard , de Leval Laurence , Morschhauser Franck , Bachy Emmanuel 
Published: February 2024

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been reported. The primary analysis of the Ro-CHOP phase III randomized controlled trial (ClinicalTrials.gov identifier: NCT01796002 ) established that romidepsin (Ro) plus cyclophosphamide, doxorubicin, vincristine, prednisone (CHOP) did not yield an increased efficacy compared with CHOP alone as first-line treatment of peripheral T-cell lymphoma. We report the planned final analysis 5 years after the last patient enrolled. With a median follow-up of 6 years, median progression-free survival (PFS) was 12.0 months compared with 10.2 months (hazard ratio [HR], 0.79 [95% CI, 0.62 to 1.005]; P = .054), while median overall survival was 62.2 months (35.7-86.6 months) and 43.8 months (30.1-70.2 months; HR, 0.88 [95% CI, 0.68 to 1.14]; P = .324) in the Ro-CHOP and CHOP arms, respectively. In an exploratory analysis, the median PFS in the centrally reviewed follicular helper T-cell lymphoma subgroup was significantly longer in the Ro-CHOP arm (19.5 v 10.6 months, HR, 0.703 [95% CI, 0.502 to 0.985]; P = .039). Second-line treatments were given to 251 patients with a median PFS2 and OS2 after relapse or progression of 3.3 months and 11.5 months, respectively. Within the limits of highly heterogeneous second-line treatments, no specific regimen seemed to provide superior disease control. However, a potential benefit was observed with brentuximab vedotin in association with chemotherapy even after excluding anaplastic large-cell lymphoma subtype or after adjusting for histology and international prognostic index in a multivariate model (HR for PFS, 0.431 [95% CI, 0.238 to 0.779]; P = .005).
Sending Language into Battle: Interview with Hortense J. Spillers
Authors: Ferreira da Silva Denise 
Published: February 2024

Abstract
In this conversation with Denise Ferreira da Silva, which unfolded over a period of twelve months, Hortense Spillers comments on critical political events and moments, which coincide with major markers in her academic trajectory. Each of these historical and personal milestones becomes, then, the backdrop against which one can appreciate how much of her thinking and writing are critical reflections and analytical interventions on questions and themes that prevailed at a given juncture. Through Spillers's comments on what has animated her writings on the Black sermon, the flesh, psychoanalysis, and Black culture, for instance, we gather the image that is the most appropriate presentation of Black thought, which is that of thinking in the thick of it.
When Hortense Spillers and Toni Morrison Meet in the Clearing: The Hieroglyphics of Marking and Unmarking
Authors: Crawford Margo Natalie 
Published: February 2024

Abstract
This essay uncovers the ties between Hortense Spillers's theory and criticism and Toni Morrison's literature. Crawford's analysis of representations of “flesh” in “Mama's Baby, Papa's Maybe” (1987) and Beloved (1987) becomes a springboard for her analysis of other connections between Spillers and Morrison. This study of the conscious and unconscious dialogue between Spillers and Morrison pivots on Spillers's annotation of a draft of Morrison's play Dreaming Emmett (1985), Spillers's groundbreaking analysis of Morrison's Sula, Morrison's turn to theory in Paradise and Jazz, and Spillers's use of creative writing in her theory and criticism. Crawford reveals the direct and indirect conversations between Spillers and Morrison and their shared commitment to finding language that breaks the boundaries between analysis and experience.
To Put Afoot a New Black Woman: On Hortense Spillers and the Possibilities of Gender
Authors: Roach Shoniqua 
Published: February 2024

Abstract
This essay maps Hortense Spillers's figurations of the black woman across three essays published in the 1980s—“Interstices,” “An Order of Constancy,” and “Mama's Baby, Papa's Maybe”—to illustrate the myriad ways in which Spillers imagines black women as vital symbolic and material forces in the (re)production of New World spaces. Situating the US 1980s as a critical geo- and sociopolitical context for Black feminist, specifically Spillersian, knowledge production, this essay puts afoot a new Spillers, demonstrating how her critical value is not exclusively tied to her interventions into symbolic and material formations of Man but rather might also be measured through her theoretical efforts on behalf of, and insights into, diverse and polymorphous communities of (Black) feminists and women. By close-reading Spillers's visionary considerations of the perils and possibilities of gender, and with attention to critical innovations in Black (trans)feminist and queer studies, this essay (re)claims the Black woman—and, by extension, Black women—as the critical and material loci of Black feminisms.
Fathers and Daughters; or, Social Reproduction in the Anthropocene
Authors: Im Seo Hee 
Published: February 2024

Abstract
Critics have argued that contemporary literature and culture fail to offer compelling alternatives to a present marred by capitalist overdevelopment and environmental destruction. This essay finds counterevidence to that claim in recent dystopian fictions such as the films Blade Runner 2049, Interstellar, Children of Men, and Train to Busan and the novel The Children of Men, which prominently feature teamwork between fathers (or father surrogates) and daughters in a world where the human species faces possible extinction. Representing care work as heroism, these works not only seek to redefine what counts as professional competence in a crisis but further model the passage of power from an exhausted patriarchy to a younger generation of women more alert to the necessity of creating a world that values reproductive labor as much as, if not more than, productive labor.
Resection of a Recurrent Lumbar Chordoma With Intradural Extension and Complex Dural Repair: 2-Dimensional Operative Video
Authors: Dada Abraham , Tawil Michael E. , Dietz Nicholas , Ambati Vardhaan S. , Chryssikos Timothy , Theologis Alekos A. , Mummaneni Praveen V. 
Published: February 2024

Chordomas are derived from embryonic notochord remnants and comprise 1%–4% of all bone tumors.
1
Nearly all chordomas arise in the axial skeleton, with 50% in the sacrococcygeal region, 35% in the skull base and 15% within mobile spine vertebrae.
1,2
Regional recurrence after en bloc surgery is common and 30%–40% of patients develop metastatic disease.
3-6
In this operative video, we present a 41-year old man who previously underwent en bloc lateral L1 corpectomy and received high-dose hybrid photon and proton radiation therapy for treatment of his L1 chordoma. On surveillance imaging, 2 years post op MRI revealed recurrence of the chordoma, now extending to the L2–3 epidural space. Further radiation alone was considered but was not performed due to lack of separation between the tumor and neural elements, thus increasing the risk of radiation-induced neurological injury. Combination revision surgical resection with subsequent boost radiation therapy was pursued instead. The technical nuances to achieve complex ventral and dorsal dural repair after removal of a transdural lumbar chordoma are shown in detail. Postoperatively, the patient had no new neurological deficits. At 13 months postoperatively, he reports no new pain, can ambulate without assistance, and completed 33 treatments of radiation therapy with proton beam.
The patient consented to the procedure and to the publication of his image.
Revealing the biocultural importance of Moringa oleifera (Moringaceae) in three villages, Kediri District, Indonesia
Authors: AFRIANTO WHISNU FEBRY , METANANDA ARYA ARISMAYA 
Published: February 2024

Abstract. Afrianto WF, Metananda AA. 2023. Revealing the biocultural importance of Moringa oleifera (Moringaceae) in three villages, Kediri District, Indonesia. Biodiversitas 24: 6942-6952. Moringa oleifera Lam. (Moringaceae) is a multi-purpose species with significant use and cultural importance. However, communities have yet to cultivate and use this plant intensively. This study aims to identify the biocultural importance of M. oleifera by the communities in Kediri District, East Java, Indonesia. The qualitative and quantitative ethnobotanical approach was carried out in three villages, namely Datengan, Cerme, and Ngablak Villages, Kediri District, East Java. Data were collected based on a survey of 60 informants through a semi-structured study, direct field observation, and in-depth interviews that were selected using snowball sampling. The results showed that M. oleifera has a score ICI of 20.19 and a UV score of 3. This plant has long been grown or grows naturally at all research locations. This plant was utilized for food, medicines, fooder feed, rituals, live fence, firewood, and most importantly, the leaves. This plant can grow in a variety of environmental circumstances and managed agroecosystem land, but it has yet to be actively grown. However, local knowledge of M. oleifera has declined, particularly among younger generations. The reason for this is that this plant species is less economically important than other agricultural goods. This M. oleifera study demonstrates the value of the cultural keystone species paradigm in landscape appraisal for conservation efforts.
Evaluating source credibility effects in health labelling using vending machines in a hospital setting
Authors: Griffiths Melda , Boivin Jacky , Powell Eryl , Bott Lewis 
Published: February 2024

Objectives
Providing advice to consumers in the form of labelling may mitigate the increased availability and low cost of foods that contribute to the obesity problem. Our objective was to test whether making the source of the health advice on the label more credible makes labelling more effective.

Methods and measures
Vending machines in different locations were stocked with healthy and unhealthy products in a hospital. Healthy products were randomly assigned to one of three conditions (i) a control condition in which no labelling was present (ii) a low source credibility label, “Lighter choices”, and (iii) a high source credibility label that included the UK National Health Service (NHS) logo and name, “NHS lighter choices”. Unhealthy products received no labelling. The outcome measure was sales volume.

Results
There were no main effects of labelling. However, there were significant interactions between labelling, vending machine location and payment type. For one location and payment type, sales of products increased in the high credibility label condition compared to control, particularly for unhealthy products, contrary to expectations.

Conclusions
Our findings suggest that high source credibility health labels (NHS endorsement) on food either have little effect, or worse, can “backfire” and lead to effects opposite to those intended. The primary limitations are the limited range of source credibility labels and the scale of the study.
Mental health during the COVID-19 pandemic and first lockdown in Lebanon: Risk factors and daily life difficulties in a multiple-crises setting
Authors: Elbejjani Martine , Mansour Sara , Hammoud Rawan A. , Ziade Catrina , Assi Batoul , Assi Ahmad , El Sayed Samya , El Hachem Rita , Kerbage Hala 
Published: February 2024

Introduction
Research from around the world shows important differences in the impact of the COVID-19 pandemic and lockdowns on mental health. This study examined the extent of mental health challenges (depressive and anxiety symptoms and daily life difficulties) and their associations with pandemic- and response-related factors during the first lockdown in Lebanon, which happened amid a severe economic crisis and socio-political turmoil.

Methods
Data come from a cross-sectional internet-based survey (May-June 2020). Association of depressive (Patient Health Questionnaire (PHQ-9)) and anxiety symptoms (Generalized Anxiety Disorder (GAD-7)) with outbreak-related worries and knowledge, information sources, and confidence and satisfaction in response measures were estimated using logistic regression adjusted for sociodemographic and socioeconomic indicators.

Results
Among 510 participants (mean age 36.1±11.3; 69.4% women), 32.3% had elevated depressive and 27.3% had elevated anxiety symptoms; younger age, unemployment, loss of employment, and lower income were related to more mental health symptoms. Most prevalent daily life challenges were feelings of uncertainty (74.5%) and financial (52.2%) and emotional (42.2%) difficulties; these and all other daily life difficulties (work-related, caregiving, and online learning) were significantly higher among participants with higher depressive and anxiety symptoms. Higher outbreak-related worries were associated with higher depressive (OR = 1.36, 95% CI = 1.20,1.53) and anxiety symptoms (OR = 1.47, 95% CI = 1.30,1.67). Higher pandemic-related knowledge, reliance on and trust in local health agencies and professionals’ information, and satisfaction and confidence regarding governmental and health institutions’ response were all related to lower mental health symptoms.

Conclusion
Results show that mental health burden in Lebanon during the first lockdown (when the COVID-19 outbreak was still minimal) is among the highest reported worldwide and highlight elevated emotional and financial tolls and widespread impact on daily life. In this high-burden and multiple-challenges context, results suggest an important role for the healthcare body, knowledge, and trust in the institutions managing the response.
Cost-effectiveness of tirofiban for acute ischemic stroke without large or medium-sized vessel occlusion: A Markov modelling analysis from the Chinese and United States perspectives
Authors: Wang Li , Zeng Yuhong , Zhou Limei , Xu Ping , Guo Xianbin , Xie Yu , Cai Junxiu , Pan Min , Tang Jie , Gong Qingtao , Su Rong , Liu Yan , Lou Yake 
Published: February 2024

Background
The RESCUE BT2 trial recently showcased the efficacy of tirofiban in treating acute ischemic stroke (AIS) without large or medium-sized vessel occlusion. To further assess the value of tirofiban from the perspectives of Chinese and US healthcare system, a study was conducted to evaluate its cost-effectiveness.

Methods
A hybrid model, integrating a short-term decision tree with a long-term Markov model, was developed to assess cost-effectiveness between tirofiban and aspirin for stroke patients without large or medium-sized vessel occlusion. Efficacy data for tirofiban was sourced from the RESCUE BT2 trial, while cost information was derived from published papers. Outcomes measured included respective cost, effectiveness, and incremental cost-effectiveness ratio (ICER). We conducted a one-way sensitivity analysis to assess the robustness of the results. Additionally, we performed probabilistic sensitivity analysis (PSA) through 10,000 Monte Carlo simulations to evaluate the uncertainties associated with the results.

Results
The study revealed that tirofiban treatment in AIS patients without large or medium-sized vessel occlusion led to a considerable reduction of 2141 Chinese Yuan (CNY) in total cost, along with a lifetime gain of 0.14 quality-adjusted life years (QALYs). In the US settings, tirofiban also exhibited a lower cost ($197,055 versus $201,984) and higher effectiveness (4.15 QALYs versus 4.06 QALYs) compared to aspirin. One-way sensitivity analysis revealed that post-stroke care costs and stroke utility had the greatest impact on ICER fluctuation in both Chinese and US settings. However, these variations did not exceed the willingness-to-pay threshold. PSA demonstrated tirofiban’s superior acceptability over aspirin in over 95% of potential scenarios.

Conclusion
Tirofiban treatment for AIS without large or medium-sized vessel occlusion appeared dominant compared to aspirin in both China and the US.