bluuebunny/crossref_metadata_2025_split huggingface dataset:
Perceptual representations mediate effects of stimulus properties on liking for music
Authors: Clemente Ana , Kaplan Thomas M. , Pearce Marcus T. 
Published: February 2024

AbstractPerceptual pleasure and its concomitant hedonic value play an essential role in everyday life, motivating behavior and thus influencing how individuals choose to spend their time and resources. However, how pleasure arises from perception of sensory information remains relatively poorly understood. In particular, research has neglected the question of how perceptual representations mediate the relationships between stimulus properties and liking (e.g., stimulus symmetry can only affect liking if it is perceived). The present research addresses this gap for the first time, analyzing perceptual and liking ratings of 96 nonmusicians (power of 0.99) and finding that perceptual representations mediate effects of feature‐based and information‐based stimulus properties on liking for a novel set of melodies varying in balance, contour, symmetry, or complexity. Moreover, variability due to individual differences and stimuli accounts for most of the variance in liking. These results have broad implications for psychological research on sensory valuation, advocating a more explicit account of random variability and the mediating role of perceptual representations of stimulus properties.
Older individuals' perspectives on the prerequisites for living at home: A mixed‐methods systematic review
Authors: Ylönen Minna , Stolt Minna , Kohanová Dominika , Suhonen Riitta 
Published: February 2024

AbstractIntroductionLiving at home for as long as possible is a central ageing policy goal. Older individuals usually expect to stay at home, if possible, and their goals regarding living at home generally include holistic wellness, prevention and treatment of ageing effects and the retention of satisfaction. Previous research on older individuals living at home has mostly focused on their physical performance, usually evaluated by healthcare professionals. However, there is limited research on older individuals' identification of the prerequisites for living at home.MethodsThe aim was to identify older individuals' views on the prerequisites for living at home. We conducted a mixed‐methods systematic review with a data‐based convergent design. We carried out a computerized search in MEDLINE (1966 to the end of August 2021) and CINAHL (1982 to the end of August 2021). All types of study designs were included. We evaluated the methodological quality of the included articles.ResultsOf the 1052 articles identified, 28 were eligible. The prerequisites for older individuals to be able to live at home include lifestyle and self‐care capability and physical, psychosocial, environmental and socio‐economic components.ConclusionThe review provided knowledge that can be used to inform measures for supporting independent at‐home living. Older individuals' perspectives on prerequisites for at‐home living are unique and individually specific. A checklist can be developed to detect individuals' singularity and the strengths and limitations impacting independent living. Therefore, assessments of each older individual's own perspective are needed to better identify the prerequisites for at‐home living.
Revision for Solid‐Body Breakage of the 3D‐Printed Implant Following Joint‐Sparing Surgery: A Technical Note
Authors: Li Zhuangzhuang , Lu Minxun , Gong Taojun , Zhou Yong , Min Li , Luo Yi , Tu Chongqi 
Published: February 2024

BackgroundThe advent of three‐dimensional (3D)‐printed custom‐made implants has revolutionized orthopaedic surgery, particularly in limb‐ and joint‐sparing surgeries. However, clinical experience in the revision for 3D‐printed implant breakage is lacking, and the revision surgery remains challenging. This study reported the revision of proximal tibial prosthetic reconstruction necessitated by solid‐body breakage of a 3D‐printed implant, aiming to detail the surgical techniques and evaluate postoperative outcomes.Case PresentationA patient diagnosed with osteosarcoma underwent joint‐sparing surgery with a 3D‐printed implant, but implant breakage occurred during subsequent follow‐up. The initial implant was broken into two parts: the proximal implant breakage part (IBP) integrated with the host bone and the distal IBP left in the prosthetic component. Four revision protocols were devised, each based on one of the four hypothesis results of taking out the initial implant. A new custom‐made implant and a series of assistance devices (“positioning devices,” “drill devices,” “tap devices,” and “separator devices”) were specifically prepared for revision surgery. The proximal IBP was taken out from the host bone, but the distal IBP was not taken out from the initial prosthetic component. The patient received the new custom‐made implant for reconstruction, with the knee joint preserved. The patient recovered uneventfully after revision surgery and achieved satisfactory function. The Musculoskeletal Tumor Society was 28 at the last follow‐up. No complications were detected during the follow‐up period.ConclusionComprehensive preoperative planning and preparation, enabling the surgeon to effectively address intraoperative challenges, are crucial for the successful revision of 3D‐printed implant breakage. It is feasible to re‐implant a 3D‐printed custom‐made implant, demonstrating satisfactory clinical and functional results.
A guide to photosynthetic gas exchange measurements: Fundamental principles, best practice and potential pitfalls
Authors: Busch Florian A. , Ainsworth Elizabeth A. , Amtmann Anna , Cavanagh Amanda P. , Driever Steven M. , Ferguson John N. , Kromdijk Johannes , Lawson Tracy , Leakey Andrew D. B. , Matthews Jack S. A. , Meacham‐Hensold Katherine , Vath Richard L. , Vialet‐Chabrand Silvere , Walker Berkley J. , Papanatsiou Maria 
Published: February 2024

AbstractGas exchange measurements enable mechanistic insights into the processes that underpin carbon and water fluxes in plant leaves which in turn inform understanding of related processes at a range of scales from individual cells to entire ecosytems. Given the importance of photosynthesis for the global climate discussion it is important to (a) foster a basic understanding of the fundamental principles underpinning the experimental methods used by the broad community, and (b) ensure best practice and correct data interpretation within the research community. In this review, we outline the biochemical and biophysical parameters of photosynthesis that can be investigated with gas exchange measurements and we provide step‐by‐step guidance on how to reliably measure them. We advise on best practices for using gas exchange equipment and highlight potential pitfalls in experimental design and data interpretation. The Supporting Information contains exemplary data sets, experimental protocols and data‐modelling routines. This review is a community effort to equip both the experimental researcher and the data modeller with a solid understanding of the theoretical basis of gas‐exchange measurements, the rationale behind different experimental protocols and the approaches to data interpretation.
Diverging cell wall strategies for drought adaptation in two maize inbreds with contrasting lodging resistance
Authors: Calderone Silvia , Mauri Nuria , Manga‐Robles Alba , Fornalé Silvia , García‐Mir Lluís , Centeno María‐Luz , Sánchez‐Retuerta Camila , Ursache Robertas , Acebes José‐Luis , Campos Narciso , García‐Angulo Penélope , Encina Antonio , Caparrós‐Ruiz David 
Published: February 2024

AbstractThe plant cell wall is a plastic structure of variable composition that constitutes the first line of defence against environmental challenges. Lodging and drought are two stressful conditions that severely impact maize yield. In a previous work, we characterised the cell walls of two maize inbreds, EA2024 (susceptible) and B73 (resistant) to stalk lodging. Here, we show that drought induces distinct phenotypical, physiological, cell wall, and transcriptional changes in the two inbreds, with B73 exhibiting lower tolerance to this stress than EA2024. In control conditions, EA2024 stalks had higher levels of cellulose, uronic acids and p‐coumarate than B73. However, upon drought EA2024 displayed increased levels of arabinose‐enriched polymers, such as pectin‐arabinans and arabinogalactan proteins, and a decreased lignin content. By contrast, B73 displayed a deeper rearrangement of cell walls upon drought, including modifications in lignin composition (increased S subunits and S/G ratio; decreased H subunits) and an increase of uronic acids. Drought induced more substantial changes in gene expression in B73 compared to EA2024, particularly in cell wall‐related genes, that were modulated in an inbred‐specific manner. Transcription factor enrichment assays unveiled inbred‐specific regulatory networks coordinating cell wall genes expression. Altogether, these findings reveal that B73 and EA2024 inbreds, with opposite stalk‐lodging phenotypes, undertake different cell wall modification strategies in response to drought. We propose that the specific cell wall composition conferring lodging resistance to B73, compromises its cell wall plasticity, and renders this inbred more susceptible to drought.
MrERF039 transcription factor plays an active role in the cold response of Medicago ruthenica as a sugar molecular switch
Authors: Fu Jiabin , Zhao Yanyun , Zhou Yan , Wang Yu , Fei Zhimin , Wang Waner , Wu Jiaming , Zhang Feng , Zhao Yan , Li Jiayu , Hao Jinfeng , Niu Yiding 
Published: February 2024

AbstractCold stress severely restricts plant development, causing significant agricultural losses. We found a critical transcription factor network in Medicago ruthenica was involved in plant adaptation to low‐temperature. APETALA2/ethylene responsive factor (AP2/ERF) transcription factor MrERF039 was transcriptionally induced by cold stress in M. ruthenica. Overexpression of MrERF039 significantly increased the glucose and maltose content, thereby improving the tolerance of M. ruthenica. MrERF039 could bind to the DRE cis‐acting element in the MrCAS15A promoter. Additionally, the methyl group of the 14th amino acid in MrERF039 was required for binding. Transcriptome analysis showed that MrERF039 acted as a sugar molecular switch, regulating numerous sugar transporters and sugar metabolism‐related genes. In addition, we found that MrERF039 could directly regulate β‐amylase gene, UDP glycosyltransferase gene, and C2H2 zinc finger protein gene expression. In conclusion, these findings suggest that high expression of MrERF039 can significantly improve the cold tolerance of M. ruthenica root tissues during cold acclimation. Our results provide a new theoretical basis and candidate genes for breeding new legume forage varieties with high resistance.
Atypical brain responses to 40‐Hz click trains in girls with Rett syndrome: Auditory steady‐state response and sustained wave
Authors: Neklyudova Anastasia , Kuramagomedova Rabiat , Voinova Victoria , Sysoeva Olga 
Published: February 2024

AimThe current study aimed to infer neurophysiological mechanisms of auditory processing in children with Rett syndrome (RTT)—rare neurodevelopmental disorders caused by MECP2 mutations. We examined two brain responses elicited by 40‐Hz click trains: auditory steady‐state response (ASSR), which reflects fine temporal analysis of auditory input, and sustained wave (SW), which is associated with integral processing of the auditory signal.MethodsWe recorded electroencephalogram findings in 43 patients with RTT (aged 2.92–17.1 years) and 43 typically developing children of the same age during 40‐Hz click train auditory stimulation, which lasted for 500 ms and was presented with interstimulus intervals of 500 to 800 ms. Mixed‐model ancova with age as a covariate was used to compare amplitude of ASSR and SW between groups, taking into account the temporal dynamics and topography of the responses.ResultsAmplitude of SW was atypically small in children with RTT starting from early childhood, with the difference from typically developing children decreasing with age. ASSR showed a different pattern of developmental changes: the between‐group difference was negligible in early childhood but increased with age as ASSR increased in the typically developing group, but not in those with RTT. Moreover, ASSR was associated with expressive speech development in patients, so that children who could use words had more pronounced ASSR.ConclusionASSR and SW show promise as noninvasive electrophysiological biomarkers of auditory processing that have clinical relevance and can shed light onto the link between genetic impairment and the RTT phenotype.
Coping target checklist for home‐based older adults living with disabilities and their spousal caregivers
Authors: Lin Xiaolu , Ou Jiexia , Wang Yanfang , Wu Yanni , Yang Lingli , Zhang Mi , Zhou Chunlan 
Published: February 2024

AbstractBackgroundThe substantial rise in the population of older adults living with disabilities is a prominent concern, presenting a profound challenge for healthcare and social welfare systems. Community‐based home care is seen as an effective approach to meet the care needs of older adults living with disabilities.ObjectiveTo construct a coping target checklist for home‐based older adults living with disabilities and their spousal caregivers.MethodsThe initial draft was developed based on a comprehensive literature review, followed by two rounds of Delphi correspondence final version.ResultsA comprehensive literature review resulted in the development of 7 modules, 20 topics. After round 1, 3 items were removed, 3 sections, 1 topic and 1 objective were new additions, 16 items were modified, split or combined. Four sections, 3 sections (Individual coping target for spousal caregivers, Individual coping target for older adults living with disabilities, and Shared coping target), 7 modules, 18 topics and 49 objectives were finally identified in round 2. The content of the list tool is derived from three perspectives: self‐management strategies for older adults living with disabilities, caregiving strategies for spousal caregivers, and combined.ConclusionsThe coping target checklist was intended to be evidence‐based and reflective of a practical direction for home‐based older adults living with disabilities and their spousal caregivers living at home.
Transcriptome analysis in mouse skin after exposure to ultraviolet radiation from a canopy sunbed
Authors: Qutob Sami S. , Roesch Samantha P. M. , Smiley Sandy , Bellier Pascale , Williams Andrew , Cook Kate B. , Meier Matthew J. , Rowan‐Carroll Andrea , Yauk Carole L. , McNamee James P. 
Published: February 2024

AbstractExposure to ultraviolet radiation (UV‐R), from both natural and artificial tanning, heightens the risk of skin cancer by inducing molecular changes in cells and tissues. Despite established transcriptional alterations at a molecular level due to UV‐R exposure, uncertainties persist regarding UV radiation characterization and subsequent genomic changes. Our study aimed to mechanistically explore dose‐ and time‐dependent gene expression changes, that may drive short‐term (e.g., sunburn) and long‐term actinic (e.g., skin cancer) consequences. Using C57BL/6N mouse skin, we analyzed transcriptomic expression following exposure to five erythemally weighted UV‐R doses (0, 5, 10, 20, and 40 mJ/cm2) emitted by a UV‐R tanning device. At 96 h post‐exposure, 5 mJ/cm2 induced 116 statistically significant differentially expressed genes (DEGs) associated with structural changes from UV‐R damage. The highest number of significant gene expression changes occurred at 6 and 48 h post‐exposure in the 20 and 40 mJ/cm2 dose groups. Notably, at 40 mJ/cm2, 13 DEGs related to skin barrier homeostasis were consistently perturbed across all timepoints. UV‐R exposure activated pathways involving oxidative stress, P53 signaling, inflammation, biotransformation, skin barrier maintenance, and innate immunity. This in vivo study's transcriptional data offers mechanistic insights into both short‐term and potential non‐threshold‐dependent long‐term health effects of UV‐R tanning.
Causal modeling in multilevel settings: A new proposal
Authors: Blanchard Thomas , Hüttemann Andreas 
Published: February 2024

AbstractAn important question for the causal modeling approach is how to integrate non‐causal dependence relations such as asymmetric supervenience into the approach. The most prominent proposal to that effect (due to Gebharter) is to treat those dependence relationships as formally analogous to causal relationships. We argue that this proposal neglects some crucial differences between causal and non‐causal dependencies, and that in the context of causal modeling non‐causal dependence relationships should be represented as mutual dependence relationships. We develop a new kind of model – “hybrid models” ‐ based on this suggestion, and formulate a set of axioms for those models. Our formalism has important implications for Kim's exclusion problem: whereas Gebharter's framework vindicates Kim's causal exclusion objection against nonreductive physicalism, our framework has no such implication, and can help non‐reductive physicalists vindicate the efficacy of high‐level properties. A further benefit of our formalism is that it yields a natural and plausible way of thinking about interventions in multi‐level contexts.
Investigating the longstanding mystery of stigma length differences between morphs of distylous plants
Authors: Trevizan R. , Oliveira P. E. , Cardoso J. C. F. 
Published: February 2024

Abstract
Longer stigmas in short‐styled morphs of distylous plants have been considered an adaptive characteristic that increases intermorph pollen deposition. The greater pollen deposition in short‐styled stigmas may be a by‐product of their longer length, making deposition effectiveness comparison between morphs unfeasible. Thus, investigating which morph has the relatively most efficient stigma (i.e., pollen deposition per unit length) can boost our understanding of the adaptive significance of longer stigmas.
Here, we compared pollen deposition between morphs relative to stigma length and assessed whether short‐styled stigmas are more, less, or equally effective in receiving pollen grains per unit length. We reviewed the literature to characterize the extent of sigma length differences between morphs using the two most speciose distylous genera as model systems: Palicourea and Psychotria (Rubiaceae). Then, we conducted a between‐morph comparison of raw and relative pollen depositions in a Palicourea rigida population.
We confirmed that short‐styled stigmas were longer than long‐styled stigmas in both Palicourea (194.31% longer) and Psychotria (52.59% longer) flowers. Furthermore, in the focal Pal. rigida, although short‐styled stigmas were 268.04% longer and received 97.04% more pollen grains than long‐styled stigmas, the relative pollen deposition had a reverse pattern, with short‐styled stigmas being two‐times less efficient in receiving pollen.
Our results indicate that the longer length of the short‐styled stigmas may have a compensatory effect, increasing the chances of pollen grains reaching the stigma and probably maintaining disassortative intermorph pollination in distylous plants.
Interoception as a function of hypnotizability during rest and a heartbeat counting task
Authors: Giusti Gioia , Zelič Žan , Callara Alejandro Luis , Sebastiani Laura , Santarcangelo Enrica L. 
Published: February 2024

AbstractThe hypnotizability‐related differences in morpho‐functional characteristics of the insula could at least partially account for the differences in interoceptive accuracy (IA) observed between high and low hypnotizable individuals (highs, lows). Our aim was to investigate interoceptive processing in highs, lows, and medium hypnotizable individuals (mediums), who represent most of the population, during a 10‐minute open eyes relaxation condition (Part 1) and three repetitions of consecutive 2‐minute open eyes, closed eyes, and heartbeat counting conditions, followed by a 2‐minute post‐counting condition (Part 2). Electrocardiogram and electroencephalogram were recorded in 14 highs, 14 mediums, and 18 lows, classified according to the Stanford Hypnotic Susceptibility Scale: Form A. Heartbeat‐evoked cortical potentials (HEP) were extracted throughout the entire session, and IA index was obtained for the heartbeat counting task (HCT). In Part 1, significant hypnotizability‐related differences were observed in the right central region in both early and late HEP components, with lows showing positive amplitudes and highs/mediums showing negative amplitudes. In Part 2, the same group differences were limited to the early component. Moreover, in the left frontal regions, only mediums modified their HEP during the counting task with respect to the open/closed eyes conditions, whereas highs displayed HEP differences between counting and post‐counting rest. HCT did not show significant group differences. In conclusion, highs and mediums seem to be more similar than mediums and lows regarding HEP, despite the absence of significant differences in HCT. Nonetheless, a negative correlation between hypnotizability scores and HEP amplitudes was observed in the regions showing group differences.
Bureaucratic overload and organizational policy triage: A comparative study of implementation agencies in five European countries
Authors: Zink Dionys , Knill Christoph , Steinebach Yves 
Published: February 2024

AbstractResearch on policy implementation traditionally has focused on understanding the success or failure of individual policies within specific contexts. Little attention has been given to the challenges that emerge from the cumulative growth of policy portfolios over time. This paper is addressing this research gap by examining the phenomenon of organizational policy triage, which occurs when implementation organizations face overload and are forced to make trade‐off decisions between the implementation of the different policies in their portfolios. We investigate empirical patterns of policy triage across 16 social and environmental implementation agencies in five European countries (Denmark, Germany, Ireland, Italy, and UK). We show that variation in policy triage can be explained by the combination of three central factors: blame‐shifting opportunities, the mobilization of external resources, and the commitment to compensate for overload by implementation authorities.