bluuebunny/crossref_metadata_2025_split huggingface dataset:
Biological aspect approach in sustainable management of coral catshark Atelomycterus marmoratus (Anonymous [Bennett], 1830) in Bali Strait, Indonesia
Authors: Lelono Tri Djoko , Bintoro Gatut , Harlyan Ledhayane Ika , Setyanto Arief , Rihmi Mihrobi Khalwatu , Rudianto Didik 
Published: January 2024

Abstract. Lelono TD, Bintoro G, Harlyan LI, Setyanto A, Rihmi MK, Rudianto D. 2023. Biological aspect approach in sustainable management of coral catshark Atelomycterus marmoratus (Anonymous [Bennett], 1830) in Bali Strait, Indonesia. Biodiversitas 24: 5873-5882. Coral catshark (Atelomycterus marmoratus) is a shark species that thrives in many coral reefs. to evaluate the biological aspects of A. marmoratus and their type of growth curve for a time series to support their sustainability. Sampling was performed from August 23rd, 2019, to March 31st, 2020. The morphological analysis was performed by recording or photographing to reduce possible errors. Then, the length-weight relationship, sex ratio, length at first captured and matured, and spawning ratio were evaluated. The present study demonstrated that the coral catshark captured in the cohort that produces two cohorts only happens in February. The sex ratio is 41.6% male and 48.4% female, which is considered healthy, whereas the remaining percentage is so severely damaged that its gender cannot be determined. The FISAT-II software analysis results in a von Bertalanffy growth formula of Lt = 76.21 (1-e-2.01(t+0.0596)) with t max = 1.49/ year and L max = 77.39 cm. They grow steadily or tend to slow down after they reach the age of 1.5 years, with an asymptotic length of 77.39 cm. The Lc value (67.5 cm) is more significant than their Lm value (53 cm), indicating that their sustainability is highly possible to maintain because only fish that have passed the spawning stage are captivated. The spawning potential rate (SPR) is 35%, with M = 0.66, E = 1.85, and F = 0.78. These results indicate that the exploitation rate of coral catshark is moderate because 20% < SPR < 40%. In conclusion, the A. marmoratus length-weight relationship is categorized as negative allometric, where the length grows faster than the weight.
A survey on awareness of the disease and pulmonary rehabilitation in bronchial asthma patients in the United Arab Emirates
Authors: Abdul Qayyum Neyyar Zainab , Alaparthi Gopala Krishna , Bairapareddy Kalyana Chakravarthy 
Published: January 2024

Background
Asthma, a prevalent and severe chronic respiratory condition, can be significantly managed and controlled through informed awareness about the disease and pulmonary rehabilitation strategies, thereby enhancing patients’ health-related quality of life.

Objective
To determine the knowledge and awareness of Bronchial asthma and pulmonary rehabilitation among asthma-diagnosed patients in the United Arab Emirates.

Methods
Utilizing a cross-sectional study design, 237 asthma patients, aged 18 and above, were recruited from the Royal NMC Hospital, Sharjah. A comprehensive questionnaire was administered, focusing on two critical domains: understanding of the disease and knowledge about pulmonary rehabilitation. Data analysis was performed using the Statistical Package for Social Sciences (SPSS) software, version 26.

Results
The majority of participants (31.6%) reported the onset of asthma before reaching two years of age. Bronchodilators emerged as the most used medication, utilized by 31.6% of the respondents. Weather conditions (34.6%) were identified as the most prevalent risk factor. Chi-square tests revealed no significant correlations between gender and knowledge about asthma (p = 0.278) or pulmonary rehabilitation awareness (p = 0.929). A negative correlation was found between age and knowledge about asthma (p<0.001), but not with pulmonary rehabilitation awareness (p = 0.731). Education demonstrated no significant association with either knowledge about asthma (p = 0.974) or awareness of pulmonary rehabilitation (p = 0.676).

Conclusion
The study implies that most people have a basic understanding of asthma. However, there are still significant gaps in their knowledge. For instance, many aren’t sure how asthma is influenced by exercise or which parts of the body are affected. Also, understanding about therapies such as lung rehabilitation, and the contributions physical therapists can make in addressing lung problems, is only average. Interestingly, these knowledge gaps are not related to a person’s age or their educational background.
Exploring causality between bone mineral density and frailty: A bidirectional Mendelian randomization study
Authors: Shen Jue-xin , Lu Yi , Meng Wei , Yu Lei , Wang Jun-kai 
Published: January 2024

Objective
The bidirectional correlation between low bone mineral density (BMD) and frailty, despite its extensive documentation, still lacks a conclusive understanding. The objective of this Mendelian randomization (MR) study is to investigate the bidirectional causal relationship between BMD and frailty.

Methods
We utilized summary statistics data for BMD at different skeletal sites—including heel BMD (e-BMD, N = 40,613), forearm BMD (FA-BMD, N = 8,143), femoral neck BMD (FN-BMD, N = 32,735), and lumbar spine BMD (LS-BMD, N = 28,489), alongside frailty index (FI, N = 175,226) data in participants of European ancestry. MR analysis in our study was conducted using well-established analytical methods, including inverse variance weighted (IVW), weighted median (WM), and MR-Egger approaches.

Results
We observed negative causal estimates between genetically predicted e-BMD (IVW β = - 0.020, 95% confidence interval (CI) = - 0.038, - 0.002, P = 0.029) and FA-BMD (IVW β = -0.035, 95% CI = -0.066, -0.004, P = 0.028) with FI. However, the results did not reach statistical significance after applying the Bonferroni correction, with a significance threshold set at P < 0.0125 (0.05/4). There was no causal effect of FN-BMD (IVW β = - 0.024, 95% CI = -0.052, 0.004, P = 0.088) and LS-BMD (IVW β = - 0.005, 95% CI = -0.034, 0.024, P = 0.749) on FI. In the reverse Mendelian randomization (MR) analysis, we observed no causal effect of FI on BMD at various skeletal sites.

Conclusion
Our study provides support for the hypothesis that low BMD may be a potential causal risk factor for frailty, but further research is needed to confirm this relationship. However, our findings did not confirm reverse causality.
Congenital dysfunction of the adrenal cortex on the background of 11β-hydroxylase deficiency
Authors: Alimetova Z. R. , Bekmansurova T. A. 
Published: January 2024

Congenital adrenal dysfunction (CHD) is a variant of hereditary fermentopathies that lead to a violation of the synthesis of cortisol in the adrenal cortex. Late diagnosis of this pathology significantly impairs the quality of life of patients, and in some cases can lead to fatal consequences. The most common form of CHD, occurring in more than 90% of cases, is due to a deficiency of 21-hydroxylase, which is responsible for the synthesis of deoxycorticosterone and 11-deoxycortisol. The prevalence of this form is 1:10,000 to 1:20,000 newborns in the world, in Russia — 1:9500. In second place is the deficiency of 11β-hydroxylase (hypertonic form of HCHD), which affects the synthesis of cortisol. This form of the disease occurs in about 1:100,000 newborns in the world, and in Russia the prevalence of this form is unknown [1].The cause of any form of CHD is mutations in the genes responsible for the synthesis of enzymes or transport proteins involved in the synthesis of cortisol. 11β-hydroxylase is synthesized in the zona fasciculata of the adrenal cortex and is regulated by adrenocorticotropic hormone by a negative feedback mechanism. 11β-hydroxylase deficiency (hypertonic form of HCHD) develops as a result of mutations in the CYP11B gene located on chromosome 8. This mutation blocks the enzymatic conversion of 11-deoxycortisol to cortisol, as well as deoxycorticosterone (DOC) to corticosterone, leading to the accumulation of DOC, which has mineralocorticoid activity. It is the excess of deoxycorticosterone that causes an increase.In 21-hydroxylase deficiency, the clinical picture is primary adrenal insufficiency (deficiency of glucoand mineralocorticoids). The clinical picture of mineralocorticoid deficiency includes salt loss syndrome: arterial hypotension, tachycardia, adynamia, fibrillary muscle twitching, dryness and decreased skin turgor, cyanosis and marbling of the skin. Glucocorticoid deficiency is manifested by muscle weakness, fatigue, hyperpigmentation of the skin. With a deficiency of 11β-hydroxylase, due to an increase in the level of deoxycorticosterone, there is no deficiency of mineralocorticoid activity, on the contrary, against the background of clinical signs of glucocorticoid insufficiency, an increase in blood pressure may be observed. Hyperandrogenism is characteristic of both forms of CHD. Symptoms of hyperandrogenism in females: virilization of the external genitalia, amenorrhea, severe alopecia and hirsutism. In undiagnosed cases of CHD, patients with a female karyotype have a male phenotype.
Re-exploration of Oslerian legacy of Osler’s address “Old Humanities and New Science”
Authors: Cao Wenhua , Yang Xiaolin 
Published: January 2024

Abstract
During the era of evidence-based medicine, the interpersonal narrative connectedness between doctors and patients is constantly under threat. In order to restore medicine’s essential inter-subjectivity and humanities, a new discipline named “narrative medicine” has risen at the beginning of the 21st century. In this context, as a historical figure full of classical thoughts of medical humanities as well as budding ideas of narrative medicine, William Osler’s thoughts has thus, once again, attracted the attention of experts and researchers in the field of medical education and clinical practice. This article puts forward the opinion that Osler’s legacy in his medical education and clinical practice has laid a solid foundation for the development of medical humanities in 20th century. The authors clarify the Oslerian legacy to the development of modern narrative medicine by expounding the essence of Osler’s last important address “Old Humanities and New Sciences”, which was delivered in 1919. The authors conclude that narrative medicine can be considered as an upgraded version of the Oslerian legacy in the transition from “evidence-based medicine” to “precision medicine”.
The research of common drought indexes for the application to the drought monitoring in the region of Jin Sha river
Authors: Zhou Xingyu , Xu Xinhui 
Published: January 2024

Abstract
Based on MODIS data from 2010 to 2020 and precipitation, air temperature, and soil moisture data of 33 meteorological stations in Jinsha River Basin from 1990 to 2020, the applicability of different remote sensing drought indexes in Jinsha River Basin was studied. These indexes include temperature condition index (TCI) and temperature vegetation drought index (TVDI), the results of vegetation condition index (VCI), vegetation supply water index (VSWI), standardized precipitation evapotranspiration index (SPEI), and standardized precipitation index (SPI) showed that TCI and TVDI, VSWI and TCI, VSWI and TVDI, VSWI and TVDI, VSWI and TVDI, VSWI and TVDI, VSWI and TVDI, SPEI and SPI, respectively. The correlation between VSWI and VCI was significant. VCI had the lowest correlation with SPEI and SPI. The average correlation coefficient between TCI and VSWI was similar. The correlation between VSWI, SPEI, and SPI was low in January, March, and October and reached significant or above levels in other months. TVDI had the highest correlation with SPEI and SPI. TVDI was significantly correlated with soil moisture every month of the year, indicating that TVDI can be effectively used for remote sensing drought monitoring in Jinsha River Basin and has strong adaptability. According to the temporal and spatial analysis of drought monitoring in the Jinsha River Basin by TVDI, the drought areas in December and January are mainly located in the middle reaches of the Jinsha River Basin, while the light drought areas are mainly located in the upper and lower reaches of the Jinsha River Basin. From March to June, the risk of severe drought increased in the middle reaches of the Jinsha River, and the moderate drought area in the Jinsha River Basin also increased. The drought from July to November was weaker than in the previous months. The moderate drought area is mainly located in the middle and lower reaches of the Jinsha River, and the mild drought area is mainly distributed in the upper reaches of the Jinsha River Basin.
The influence of language contact and ethnic identification on Chinese as a second language learners’ oral proficiency
Authors: Ziyi An , Yang Frank Gong , Mo Chen 
Published: January 2024

Abstract
Language contact is widely recognized as a factor that can have a significant impact on second language (L2) learners’ oral proficiency. However, the existing literature on this topic lacks consistency regarding the extent to which language contact can affect L2 oral outcomes. To address this issue, the present study investigates the role of ethnic identification as a mediating factor in the context of Chinese as a second language (CSL). By utilizing structural equation models (SEMs), this study reveals that: (1) language contact can directly affect Chinese oral proficiency, with interactive contact having a particular impact on oral fluency; (2) language contact indirectly affects CSL learners’ oral acquisition through ethnic identification, especially in terms of oral complexity and accuracy; and (3) language contact significantly influences ethnic identification. By constructing models that explore the relationships among language contact, ethnic identification, and Chinese oral proficiency, this study contributes to current theories of language contact in the L2 acquisition domain by highlighting the crucial role of ethnic identification.
Optimizing genetic prediction: Define-by-run DL approach in DNA sequencing
Authors: Mohammed Raghad K. , Alrawi Azmi Tawfeq Hussein , Dawood Ali Jbaeer 
Published: January 2024

Abstract
The utility of DNA sequencing in diagnosing and prognosis of diseases is vital for assessing the risk of genetic disorders, particularly for asymptomatic individuals with a genetic predisposition. Such diagnostic approaches are integral in guiding health and lifestyle decisions and preparing families with the necessary foreknowledge to anticipate potential genetic abnormalities. The present study explores implementing a define-by-run deep learning (DL) model optimized using the Tree-structured Parzen estimator algorithm to enhance the precision of genetic diagnostic tools. Unlike conventional models, the define-by-run model bolsters accuracy through dynamic adaptation to data during the learning process and iterative optimization of critical hyperparameters, such as layer count, neuron count per layer, learning rate, and batch size. Utilizing a diverse dataset comprising DNA sequences from two distinct groups: patients diagnosed with breast cancer and a control group of healthy individuals. The model showcased remarkable performance, with accuracy, precision, recall, F1-score, and area under the curve metrics reaching 0.871, 0.872, 0.871, 0.872, and 0.95, respectively, outperforming previous models. These findings underscore the significant potential of DL techniques in amplifying the accuracy of disease diagnosis and prognosis through DNA sequencing, indicating substantial advancements in personalized medicine and genetic counseling. Collectively, the findings of this investigation suggest that DL presents transformative potential in the landscape of genetic disorder diagnosis and management.
Digital Platforms and the Right to Just and Favorable Conditions of Work: A Business and Human Rights Perspective
Authors: Jędrzejowska-Schiffauer Izabela , Szoszkiewicz Łukasz 
Published: January 2024

Abstract
Digital platform economy has radically changed the modes in which work is organized, stretching the functionality of legal environment of work and its governance. This article builds on a strand of labor law scholarship that advances the need to rethink the legal construction of work and work relationship in order to adapt it to the dynamically evolving socio-economic context. By applying a business and human rights lens to this process, this article confutes the mainstream argument that labor rights guarantees remain contingent on an individual’s enjoying the status of an employee under national jurisdiction. We survey a largely underexamined conception of affording protection to platform workers under International Human Rights Law (IHRL). In doing so, we argue that the instruments of IHRL may in some respects be even better placed than that of national law, both strengthening and complementing areas where state protection is weak or non-existent. Through the right to just and favorable conditions of work perspective, we outline the non-contested, albeit partly poorly implemented obligations of states, as well as largely contentious and contested responsibilities of private actors such as digital platforms towards the rights-holders. We conclude by arguing that the leverage offered by IHRL in the struggle to curb a quasi-sovereign power of the platform largely outweighs the democratically motivated objections this avenue may raise.
Rationality of the Terrorist Group and Government’s Policy: A Game Theoretic Approach
Authors: Harichandan Aishwarya 
Published: January 2024

Abstract
The two ideas of the rationality of terrorist organisations and the costly leader game are used in this paper to construct a game theoretic model. It is an addition to the literature on terrorism and leader-follower games, in which the government and a terrorist organisation are the two players. Terrorist group can be rational or irrational. In case it is rational, it does the cost-benefit analysis and is open to negotiation. Only in this case, the government chooses to not spend on counter-terrorist measures. The irrational group has lexicographic preferences, which means that it prefers a successful attack to attract attention and recruits at the beginning or finish of its operation. Consequently, it is assumed that the irrational group will always attack. the irrational terrorist organisation has the option of either choosing not to mimic the rational group or choosing to do so at a psychological cost. Although the irrational group dislikes imitation. It seeks to duplicate the rational group so that the government withdraws and cuts back on spending on counter-terrorism. A costly leader model is set up in the paper, where the government can incur a cost to gather information about the type of terrorist group. In this framework, the paper provides policy prescriptions concerning counter-terrorist measures that the government should take in case the type of terrorist group being rational or irrational is unknown and it highlights the importance of intelligence.
Antiphospholipid antibodies as a potential factor of tumor progression
Authors: Aslanova Z. D. , Khizroeva J. Kh. , Solopova A. G. , Bitsadze V. O. , Vorobev A. V. , Gris J.-C. , Elalamy I. , Makatsariya N. A. , Zabolotnaya D. Yu. 
Published: January 2024

Introduction. Current generally accepted clinical and laboratory criteria for antiphospholipid syndrome (APS) have been clearly determined, which include vascular thrombosis and pregnancy complications in patients with circulating antiphospholipid antibodies (aPLs). However, in the last several years, aPLs have become a common finding in patients with malignancies. Accumulating data provide strong evidence for such association and suggests that thrombosis in cancer patients may be related to aPLs activity. According to global publications, aPLs circulation in cancer patients varies from 15 to 74 %, which may be due to differences in clinical characteristics of cancer patients examined as well as distinct interpretations on aPLs diagnostic tests.Aim: to determine aPLs profile in patients with malignant neoplasms of the female reproductive system, identify an association between aPLs and thrombosis as well as degree of disease progression and outcome.Materials and Methods. A single-center observational study was conducted with 130 women, among which 70 subjects had adenocarcinoma of the uterine body, cervix and ovaries. 60 age-matched apparently healthy women lacking thrombotic complications were included into control group. All study participants were examined for circulating lupus anticoagulantas well as anti-cardiolipin antibodies (aCLs), anti-β2-glycoprotein 1 antibodies (anti-β2-GР1), annexin V antibodies, and anti-phosphatidylserine-prothrombin complex antibodies (anti-PS-PT) IgG and IgM by using enzyme-linked immunosorbent assay.Results. Moderate or low aPLs titers were found in 34.2 % of patients with uterine, cervical and ovarian cancer. Ten (14.2 %) of 70 women in main study group had thrombosis so that aPLs were detected only in 5 of 10 women with thrombosis. No significant differences between patients with thrombosis and without thrombotic complications in gynecological cancer were observed. In addition, assessed parameters had no impact on relapse-free survival in cancer patients. However, a significant relation was found between circulating aCLs (IgG, IgM) and anti-PS-PT (IgG, IgM) as well as degree of oncological process. In addition, a significant association was found between aCLs isotype IgG (p = 0.017) and disease relapse.Conclusion. Although thrombosis along with acute thrombosis is a hallmark of APS patients, they demonstrate other non-thrombotic manifestations, one of which is the impact on tumor growth invasion and progression.
A Study On Talent Management Practicesimpact On Employee Job Performance In Information Technology Industry
Authors: G.J Precila  , Dr. R.Sakthivel  
Published: January 2024

The paper aims at understanding the Talent Management Practices followed in IT Industry and how it influences job performance of Employees with special reference in Chennai City, Tamilnadu. Human capital plays a very important role and hence the present study aims at apply the talent management practice and measure the job performance of them. The study also attempts to analyze various factors contributing to job performance. A well – structured questionnaire measures the responses and majority of the respondents are star performers. The Questionnaire has been validated to examine the relationship between various factors.The results elucidate that providing good working condition to employees, giving full autonomy to employees, encouraging employees to participate in discussions, arranging need based trainings to employees, giving the rewards and good recognition for employees, adopting fair and effective performance appraisal method for employees and providing feedback to employees on their performance are main talent management practices adopted by Information Technology (IT)sector. Significant difference is there among talent management practices in IT sector and socio-economic profile of employees. Performance of employees is positively, moderately and significantly related with talent management practices in IT sector, Therefore, IT companies should give adequate salary and perks to employees and they must have flexible working hours for employees. Besides, IT companies should give due respect to emotions and feelings of employees..