bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Effect of Urea Nitrogen/Creatinin Ratio Level on in Hospital Mortality and One Year Mortality of Patients with ST Segment elevation Myocardial Infarction undergone thrombolytic therapy
Authors: Bodagh Haleh , Yousefzadeh Asma , Ghanivash Amin , Banisefid Erfan , Hamzezadeh Sina , Moghadamziabari Seyedehyasmin , Seifimansour Sina , Khiavi Shila Mosadeghi , Parizad Razieh , Bodagh Mohammad bagher 
Published: November 2023

Abstract
Introduction & Objective: Considering the increasing prevalence of ST-elevation myocardial infarction (STE-MI) and its health care costs and clinical consequences, as well as the fact that kidney problems are among the most common cases in these patients, treatment system and the evaluation of its functional improvement will be considered, Therefore, in the present study, we intend to investigate the effect of blood urea nitrogen to creatinin ratio (BUN/Cr) on in-hospital mortality (IHM) and one-year mortality of patients diagnosed with STEMI undergoing thrombolytic treatment.
Materials and Methods: This descriptive cross-sectional descriptive study was conducted in in Shahid Madani, University of Medical Science, Tabriz, Iran in 2021. A list of patients diagnosed with STEMI and received thrombolytic treatments in 2017- 2019 were compiled. The file was included in the study and analyzed taking into account the inclusion and exclusion criteria.
A checklist was used to collect the data. Data were analyzed using SPSS-15 software and descriptive and inferential statistics.
Results: The results of the present study showed that blood BUN/Cr tolevel had no association with IHM and one-year mortality of STEMI patients who underwent thrombolytic treatment. There was also no association between the BUN/Cr ratio and in-hospital complications such as heart failure (HF) and cardiogenic shock (CS).
Conclusion: we found that BUN/Cr ratio is not a reliable prognostic factor for mortality and hospital complications in STEMI patients.
Molecular Characterization of Haemonchus contortus in sheep from Palani Hills, Tamil Nadu, India, based on the genes encoding COI and Cysteine Proteinase
Authors: Nagarajan Govindasamy , Pachaiyappan K. , Thirumaran S.M.K. , Thirumurugan P. , Kanakarajadurai K. , Vannish M. Ram 
Published: November 2023

Abstract

The present study is carried out with the objective to find out the helminthic parasite inhabitating the abomasums of sheep being maintained at SRRC (ICAR-CSWRI), Mannavanur, Palani Hills, Tamil Nadu, India using the morphological examination and the cytochrome c oxidase subunit I (COI) and cysteine proteinase (CP) genes based polymerase chain reaction (PCR). During the first week of December 2021, an Avikalin sheep at SRRC, Mannavanur, died due to severe anaemia. Upon the post mortem examination, the abomasum of the dead sheep was having plenty of round worms. Upon the traditional morphological examination, the worms were identified as Haemonchus contortus, based on the characteristic spicules in the posterior end of male worm and vulvar flap in the female worms. For further molecular analysis, the worms preserved in 70% alcohol and Trizol™ reagent were thoroughly ground to make a fine powder using liquid Nitrogen for the isolation of the worm’s total genomic DNA and cellular RNA respectively using the commercially available kits. By conventional PCR, COI and cysteine proteinase (hmcp6) genes of H.contortus were amplified by using the worms DNA and cDNA, respectively. After gel purification, the PCR amplified DNA fragments representing COI and cysteine proteinase gene of H.contortus were cloned into pGEM®-T and pTZ57R/T vectors, respectively. The positive recombinant plasmids were eventually subjected to Sanger sequencing method. Both the nucleotide sequences encoding COI and cysteine proteinase of H.contortus in Sheep from Palani hills, Tamil Nadu, India, were analysed using the standard Bioinformatics tools. Based on the morphological examination, sequencing and phylogenetic analysis, it was concluded that the nematode infecting the abomasums of sheep in the present study is H.contortus.
Challenging Steroid Shift in Neuronavigation - a clinical study proposal
Authors: Roy Amrit , Maschke Svenja , Warade Abhijit , Misra Basant Kumar 
Published: November 2023

Abstract
The intraoperative orientation for neurosurgeons is routinely aided by tools such as neuronavigation. For this purpose, imaging data of the head are referenced to the patient's fixed head with the aid of electromagnetically or optically recorded surface points. However, a certain susceptibility for inaccuracy remains.
Steroids such as dexamethasone are routinely given to reduce perifocal edema. Clinical improvement as well as reduction of edema can be observed radiologically just hours after steroid application – also making it a preoperative potential source of metric inaccuracy.
The effect of steroids on tissue and tumoral shift on neuronavigation has not been quantified to date. While there are several reasons for navigation inacurracy, this type of shift is often forgotten and not accounted for, but could be easily corrected. We propose the need to perform an additional preoperative cranial MRI (cMRI) shortly before the biopsy/resection in patients who have received steroids due to perifocal cerebral edema to (1) quantify and (2) compensate for steroid induced tumor shift and thereby improve inaccuracies of neuronavigation.
Proof-of-Principle for implementation of ground larviciding in the Nkam- Wouri river basin in Cameroon: Simulium larval susceptibility to temephos and effect of ten weeks treatment of the Mbende tributary on larval density and simulium biting rate
Authors: Abong Raphael Awah , Ekanya Relindis , Fombad Fanny Fri , Amambo Glory , Innocentia Ngong , Nji Theobald Mue , Nietcho Franck Noel , Deribe Kebede , Benjamin Biholong , Flobert Njiokou , Ekobo Same , Wondji Charles , Wanji Samuel 
Published: November 2023

Abstract
Background
Onchocerciasis transmission in some endemic foci has been persistent despite over 18 years of annual ivermectin mass drug administration (Ivm-MDA). Several reasons including poor adherence to ivermectin intake due to fear of severe adverse events (SAEs) in areas of co-infection with loiasis and the presence of numerous breeding sites enhancing abundant vector population contribute to this persistent transmission. The change in paradigm from onchocerciasis control to elimination may not be achieved if alternative control measures are not used. There is therefore a need to complement Ivm-MDA with other strategies like vector control. In this study, we experimented the effect of ten weeks ground larviciding with temephos on the larval density and vector population.
Method
Black flies breeding sites along the course of rivers within the study area were identified. Susceptibility test was done on freshly collected larvae by exposing them to different concentrations of temephos and assessing mortality rates. Flies were collected at two points (Mbende and Dimbong) to determine the biting density. Fishing was used to assess vertebrate aquatic fauna at river Mbende while invertebrate fauna was assessed during collection of larvae as they are usually found on same substrate as the larvae. Ground larviciding was done using the spraying method at two dosing points.
Results
Six breeding sites were identified with larvae of Simulium species. As the concentration of temephos was decreasing (0.1 to 0.001Mg/L), the mortality of larvae also decreased with a 100% mortality observed at concentrations between 0.1 to 0.025 Mg/L. The non-target fauna included various fish species, crabs, crayfish, and invertebrate fauna. Simulium larvae were totally cleared from their breeding sites and there was a steady reduction in the biting density at the collection point from week 1 through week 10 with biting rate as high as 900 flies/man/day at the beginning to 180 flies/man/day at the end of ground larviciding.
Conclusion
Simulium larvae in the study area are susceptible to temephos. Total clearance of larvae and visible reduction (82.8%) in the Simulium biting density were observed during the study.
Development of an acid-resistant solid-base catalyst for polycarbonate phenolysis
Authors: Naito Ken , Kakuta Yusuke , Kamesako Iku , Suzuki Keitaro , Hirata Momoko , Kurihara Kiyofumi 
Published: November 2023

Abstract
The phenolysis of polycarbonate using solid-base catalysts results in the depolymerization of polycarbonate into its precursors, i.e., bisphenol A and diphenyl carbonate, giving it potential applications in chemical recycling. Owing to the high acidity of phenol, solid-base catalysts must exhibit acid resistance. We evaluated the catalytic activity and leaching resistance of solid-base catalysts in the phenolysis of polycarbonate. The results indicated a tendency for increased leaching with larger metal ion radii among the synthesized solid-base catalysts. Nonetheless, MgO, which had a small metal ion radius, exhibited excellent leaching resistance. However, owing to the acidic nature of phenol, MgO was deactivated by the adsorption of phenol on its basic sites. Immobilizing MgO on an acidic support reduced its basic strength, inhibiting phenol adsorption and mitigating deactivation. Notably, MgO/Al2O3 was identified as a catalyst with an optimal basic strength for both catalytic activity and deactivation suppression.
Identification of molecular subtypes based on tumor-specific genes in melanoma and development of a nomogram for prognostic prediction in patients with melanoma
Authors: Hong Ye , Mao Lei , Li Nan , Mu Dan 
Published: November 2023

Abstract
Purpose
We aim to investigate the molecular characteristics of melanoma by analyzing tumor-specific genomic signatures and construct a nomogram for prognostic prediction in patients with melanoma.
Methods
The datasets of melanoma and normal skin tissue from the Genotype-Tissue Expression and the Cancer Genome Atlas databases were merged to conduct differential gene expression (DEGs) analysis. Cox regression and LASSO regression analysis were used to identify tumor-specific genes associated with prognosis and construct a risk score model. Melanoma patients in the training and validation cohorts were grouped into high-risk and low- risk groups according to the median value of risk score. K-M analysis, Gene Set Enrichment Analysis and single-sample Gene Set Enrichment Analysis were conducted to further analyze the differences of the survival, the enriched pathways, the tumor microenvironment, the hypoxia score, the tumor mutation burden and the gene mutation between high and low risk groups. A nomogram based on risk score and tumor stage was constructed for prognostic prediction in patients with melanoma.
Results
Seven DEGs including BCAN, CFAP61, CXCL13, KIT, KRT17, PLA1A, and PPP1R3C were identified to construct the risk score model. Patients in the high-risk group showed inferior survival compared with the low-risk group. The oxidative phosphorylation, the metabolism of xenobiotics by cytochrome P450, the tyrosine metabolism, the fructose and mannose metabolism, the glycolysis/gluconeogenesis and the melanogenesis pathways were significantly enriched in high-risk group patients. The high-risk and low-risk groups differed in terms of angiogenesis, anti-tumor and pro-tumor cytokines, B cells, T cells, M1 signature, myeloid cells traffic NK cells, Th1 and Th2 signature, Treg, tumor associated macrophage, coactivation, check point molecules, effector cells. The AUC values for the nomogram predicting the survival of melanoma patients at 12, 24, 36, and 60 months were 0.726, 0.791, 0.712, and 0.714, respectively.
Conclusion
This study provides a personalized assessment of molecular subtypes in melanoma. The nomogram based on the seven tumor-specific genes and tumor stage had favorable predictive value in melanoma.
Use of Ultraviolet Spectrometer to Determine the Absorbance, Refractive Index, Electric Conductivity Permittivity beside Magnetic Permeability
Authors: Mahmoud HassabAlla M. A. , Abdalgadir LM 
Published: November 2023

Abstract
Solar cells are nowadays one of the most important issues that facing scientists. This is because they represent the best alternative that can replace petrol fuel. This encourages scientists to do intensive work to increase the efficiency of solar cells. Motivated by this urgent need for high-efficiency solar cells this work was done by preparing 5 samples of carbon doped with Aluminum oxide with different molar concentrations (0.1,0.3,0.5,0.7,0.9). The aim of this work is to characterize these samples to see how they can used as solar cells. The crystal and nanostructure have been characterized by using X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) techniques. The optical and electrical properties were characterized using an ultraviolet-visible spectrometer. The performance of a solar cell was tested using a simple electric circuit. The results of NixAL2(1-x)O4 samples indicate that the decreasing of Ni concentration (X) decreases the energy gap while the nanocrystal size, d-spacing, mass density, absorption coefficient, and solar cell efficiency increase. All the solar cell samples of this specimen exhibited a voltage of 1.184mV, an open-circuit voltage of 1.440mV, a fill factor of 0.73, and an efficiency range from 1.8642% up to 2.2460% according to the different concentrations.
Structural analysis of Green Human Resource Management and Green Transformational Leadership on Environmental Behaviors and Green Innovation Performance with the Mediating Role of Environmental Knowledge
Authors: Balouch Salim , Yekan Tayyebeh Vakili , Tamandani Salimeh Kordi 
Published: November 2023

Abstract
Continuous and sustainable growth has become a daily norm, putting increasing pressure on organizations to adopt green practices to achieve sustainable competitive advantages. Therefore, this research aimed to analyze the structural relationship between GHRM and GTL on EBs and GIP with the mediating role of EK. The research method was developmental-applied in terms of purpose and descriptive-correlational in terms of research design, using a structural equation modeling approach. The statistical population consisted of all primary school teachers in Urmia city, Iran (Urmia city districts one and two) during the academic year 2022–2023. A one-stage cluster sampling method was used, and the sample size was determined to be 338 individuals using Morgan's table. Standard questionnaires were used to collect the required data, including the questionnaire by Zid et al. (2018) for GHRM, Zhang & Wang (2020) for GTL, Roberson, and Carleton (2018) for EBs, Chen et al. (2013) for GIP, and Me et al. (2012) for EK. Content validity of the research was ensured through the opinions of educational science professors, and the reliability of the questionnaires was confirmed using Cronbach's alpha coefficient, which yielded values of 0.90, 0.77, 0.79, 0.82, and 0.70, respectively. The data were analyzed using Pearson correlation coefficient, structural equation modeling, and confirmatory factor analysis with SPSS 28 and Smart PLS 3 software. The results of the research indicated a significant positive direct relationship between GHRM and GIP. There was a positive direct relationship between GTL and GIP. A positive direct relationship was found between GTL and EBs. However, there was no significant relationship between GHRM and EBs. There was an indirect non-significant relationship between GHRM and EBs with the mediating role of EK. There was no indirect relationship between GTL and GIP with the mediating role of EK. There was no indirect relationship between GTL and EBs with the mediating role of EK.
OsJAZ5 promotes salt tolerance in rice and physical interactions with OsMYL1 and OsMYL2 stimulate jasmonic acid signaling
Authors: Ma Guangming , zhang Yong , Liu Jing , Zhao Kunhong , Zhang Chun , Chen Moxian , Kandegama Wishwajith , Sun Yao , Li Xiangyang 
Published: November 2023

Abstract
Salt stress is one of the main abiotic stresses that affect plants. The jasmonic acid (JA) signaling pathway is an important pathway that converts the normal growth state into the stress state when plant cells encounter abiotic stress. OsJAZ5 is a JAZ protein family gene, but how the JA signaling pathway promotes rice responses to salt stress is unclear. In this study, after screening for the OsJAZ5 gene, a yeast function analysis using the yeast mutant Axt3k was performed to determine its salt resistance sensitivity. The phenotype analysis showed that it was overexpressed in rice and promoted growth under salt stress. An analysis of the superoxide dismutase, peroxidase, phenylalanine ammonolyase, and catalase activities showed that the OE-3 and OE-5 lines promoted OsJAZ5 activity to maintain the reactive oxygen species dynamic balance under salt stress. In addition, the protein-protein interaction analysis and protein-protein docking confirmed that OsJAZ5 interacts with OsMYL1 and OsMYL2, demonstrated that OsJAZ5 promotes reactions by OsMYL1, OsMYL2, and OsMYC2 and that their expressions were further enhanced by OsJAZ5 through JA signaling of OsMYC2. Thus, expression of the JA signaling response gene was activated by salt stress and its effect on OsJAZ5 promoted salt tolerance in rice.
Solution of Gaussian and Advection Diffusion Equation in Linear k-profile
Authors: Essa Khaled , Mosallem Ahmed M. 
Published: November 2023

Abstract
In this research, we solved the advection-diffusion equation in three dimensions taking the vertical turbulent as a function in linear of vertical and downwind distance. comparing between the Gaussian, predicted models and observed concentrations of Iodine-131 (I131) which measuring through Egyptian Atomic Energy Authority (EAEA) in neutral case.
Long-Term Quality of Life after Hybrid Robot-assisted and Open Ivor Lewis Esophagectomy for Esophageal Cancer in a Single Center: a Comparative Analysis
Authors: Neuschütz Kerstin J. , Fourie Lana , Germann Nicolas , Pieters Anouk , Däster Silvio , Angehrn Fiorenzo V. , Klasen Jennifer M. , Müller-Stich Beat P. , Steinemann Daniel C. , Bolli Martin 
Published: November 2023

Abstract
Purpose
Due to improved survival of esophageal cancer patients, long-term quality of life (QoL) is increasingly gaining importance. We analyzed QoL of patients treated with open Ivor Lewis esophagectomy (Open-E) or a hybrid operation including laparotomy and a robot-assisted thoracic phase (hRob-E), as well as a standard group of healthy individuals.
Methods
With a median follow-up of 36 months after hRob-E (n = 28) and 40 months after Open-E (n = 43), patients´ QoL was assessed using the European Organization for Research and Treatment of Cancer (EORTC) QoL Questionnaire Core 30 (QLQ-C30) and the EORTC Esophagus specific QoL questionnaire 18 (QLQ-OES18).
Results
Patients showed similar clinical-pathological characteristics, but hRob-E patients had significantly higher ASA scores at surgery (p < 0.001). Patients and healthy controls reported similar global health status, emotional and cognitive functions. However, physical functioning of Open-E patients was significantly reduced compared to healthy controls (p = 0.019). Operated patients reported reduced role and social functioning, fatigue, nausea and vomiting, dyspnea and diarrhea. A trend towards a better pain score after hRob-E compared to Open-E emerged (p = 0.063). Regarding QLQ-OES18, hRob-E and Open-E treated patients similarly reported eating problems, reflux, and troubles swallowing saliva.
Conclusions
The general health status is not impaired after esophagectomy. Despite higher ASA scores, QoL of hRob-E patients is similar to that of patients operated with Open-E. Moreover, patients after hRob-E appear to have a better score regarding physical functioning and a better pain profile than patients after Open-E, indicating a benefit of minimally invasive surgery.
Deep Reinforcement Learning solution for Scheduling critical notifications in a Digital Twin cluster
Authors: Vrbaski Mira , Bolic Miodrag , Majumdar Shikharesh 
Published: November 2023

Abstract

A Scheduling approach for a Critical Monitoring System in a Digital Twin (DT) cluster based on Deep Reinforcement Learning (DRL) is presented. Recent advances in the DRL field inspired us to research how to build a solution that learns to manage the cloud container’s resources directly from experience. The paper presents a multi-objective Scheduling approach for containerized microservice Critical Notification system applications based on DRL (SCN-DRL), where Neural Networks (NN) are used RL Agents. This paper implements, compares and evaluates three Neural Networks (NN) that: a) provide scheduling of the DT cluster’s notification jobs, b) outperform state-of-art heuristics, and c) keep steady performance when notification workload increases from 10 to 90%. Furthermore, resilience to resource container failures is a critical component of the distributed system; our proposed research shows that SCN-DRL is resilient to sudden resource drops by 10%.
Classification and Phylogenetic Relationship Identification of Weigela Plants Using DNA Barcoding Technology
Authors: Wang J X , Shi B S , Zhou X H , Liu Y L , Li J Q , Zhang J , Zhang X Y 
Published: November 2023

Abstract
DNA barcoding technology is widely used in the classification and identification of plant germplasm. In this study, the chloroplast gene intergenic spacer trnC-petN and the nuclear gene intergenic spacer ITS2 were selected as DNA barcodes to identify 31 germplasm resources of the Weigela. The amplification and sequencing success rates for both primers were 100%. Based on the individual use of trnC-petN and ITS2, the accuracy was 66.76% and 75.56%, respectively. Both primers could accurately classify and identify most germplasm, but the accuracy for individual materials was relatively low. The combined analysis of trnC-petN and ITS2 divided the experimental materials of the Weigela into four groups: W. florida 'Red Prince' group, Weigela florida group, Weigela praecox group, and W. florida 'Linglong' group, with a high accuracy of 83.68%. The combined method, incorporating clustering results from individual markers, demonstrated higher accuracy than individual molecular markers, providing a better classification and identification of germplasm resources and their genetic relationships within the Weigela.
Lights, Camera, Mirror, Action! Toolbox for Motion Capture of Rapid Maneuvers using a Single High Speed Camera and a Planar Mirror
Authors: Hussain Wajahat , Naveed Mahum , Khan Asad , Khan Taimoor Hasan , Anjum Muhammad Latif , Rasool Shahzad , Maqsood Adnan 
Published: November 2023

Abstract
Motion capture options at a high rate, e.g., kinematics of flying organisms, are limited. Inertial sensors or marker based tracking is infeasible due to the mounting requirement. The advent of high-speed cameras being made available for commercial use has facilitated the discovery of intriguing high rate behaviors. However, analyzing rapid kinematics in three dimensions necessitates using two or more high-speed cameras, which are specialized equipment and come at a significant expense. In this study, we utilize a conventional methodology of capturing synchronized multiple views using a solitary camera and a planar mirror. We introduce a user-friendly software package that facilitates the calibration of this economical setup, enables the three-dimensional (3D) analysis of high-rate maneuvers and automatic tracking over long video sequences. Within ~15 minutes, a single high-speed camera is calibrated and can be used to acquire 3D data. We accompany the toolbox with a detailed user guide and video tutorial (https://tinyurl.com/yckm9y6b) for ease of use. We accurately reconstruct dense tracks for multiple high rate maneuvers including flying insect species (dragonfly, butterfly and housefly), spinning coin and rotating fan blades.