bluuebunny/crossref_metadata_2025_split huggingface dataset:
Post‐Traumatic Migraine: Chronic Migraine Precipitated by Minor Head or Neck Trauma
Authors: Weiss Howard D. , Stern Barney J. , Goldberg Jorge 
Published: May 2005

SYNOPSISMinor trauma to the head or neck is occasionally followed by severe chronic headaches. We have evaluated 35 adults (27 women, 8 men) with no prior history of headaches, who developed recurrent episodic attacks typical of common or classic migraine following minor head or neck injuries (“posttraumatic migraine” ‐ PTM). The median age of these patients was 38 years (range 17 to 63 years), which is older than the usual age at onset of idiopathic migraine. The trauma was relatively minor: 14 patients experienced head trauma with brief loss of consciousness, 14 patients sustained head trauma without loss of consciousness, and 7 patients had a “whiplash” neck injury with no documented head trauma. Headaches began immediately or within the first few days after the injury. PTM typically recurred several times per week and was often incapacitating. The patients had been unsuccessfully treated by other physicians, and there was a median delay of 4 months (range I to 30 months) before the diagnosis of PTM was suspected. The response to prophylactic anti‐migraine medication (propranolol or amitriptyline used alone or in combination) was gratifying, with 21 of 30 adequately treated patients (70%) reporting dramatic reduction in the frequency and severity of their headaches. Improvement was noted in 18 of the 23 patients (78%) who were still involved in litigation at the time of treatment. The neurologic literature has placed excessive emphasis on compensation neurosis and psychological factors in the etiology of chronic headaches after minor trauma. Physicians must be aware of PTM, as it is both common and treatable.
Autonomic Nervous System Function in Migraine Without Aura
Authors: Cortelli Pietro , Pierangeli Giulia , Parchi Piero , Contin Manuela , Baruzzi Agostino , Lugaresi Elio 
Published: May 2005

SYNOPSISAutonomic nervous system functions were studied in 13 females with migraine without aura during headache‐free intervals, using physiological, pharmacological and biochemical methods.Heart‐rate in the resting condition and blood pressure rises in the cold‐face and isometric handgrip tests were higher than in controls. Normal cardiovascular responses to the Valsalva manoeuvre and to noradrenaline infusion suggest that the baroreflex arc is intact. Normal heart rate responses to the Valsalva manoeuvre, to the cold‐face test and to deep breathing confirmed a normal cardiac parasympathetic function. Clonidine infusion showed a sedative and depressor effect and an inhibition of plasma NA similar to those occurring in controls, suggesting a normal central sympathetic tone. As a whole, the physiological, pharmacological and biochemical tests were consistent with a non‐specific sympathetic hyperactivity, but do not confirm any impairment of the autonomic control of the cardiovascular system in migraine patients in headache‐free intervals.
Ketorolac in Acute Headache Management
Authors: Harden R. Norman , Carter Timothy D. , Gilman Charles S. , Gross Alan J. , Peters John R. 
Published: May 2005

SYNOPSISTwelve patients presenting to an emergency department in headache crisis were treated with Ketorolac tromethamine 60 mg. intramuscularly. All improved sufficiently to require no further emergent treatment. There was statistically significant improvement on all segments of the short form McGill Pain Questionnaire. This open label trial suggests that Ketorolac Tromethamine may be a useful agent in the treatment of heed‐ache crisis, and a controlled study to examine this is warranted.
Home‐Based Multicomponent Treatment of Pediatric Migraine
Authors: Allen Keith D. , McKeen Lenora R. 
Published: May 2005

SYNOPSISThe present investigation examined a home‐based multicomponent treatment program incorporating biobehavioral technology in the treatment of pediatric migraine. Twenty‐one children ages 7–12 participated in home‐based practice of thermal biofeedback while parents implemented guidelines designed to encourage the use of biofeedback and eliminate support for maladaptive pain behavior. Treatment was introduced sequentially across three groups of children in a multiple baseline design. When subjects and their families were complaint with treatment recommendations, 87% of the children experienced clinically significant reductions in headache activity, with these reductions maintained at 3 and 8 month followups. Treatment outcome was found to be closely related to frequency of home practice, parental support for the use of adaptive coping (biofeedback) rather than maladaptive coping (pain) behaviors, and ability to warm hands. Discussion is provided concerning potential mechanisms of action and directions for future research.
Pheochromocytoma Presenting with Headache, Panic Attacks and Jaundice in a Child
Authors: Gökçe Özcan , Gökçe Çigdem , Günel Salih , Arisoy Sami , Arisoy Engin , Hüseyinoglu Kemal , Kismet Kemal , Uçar Özcan 
Published: May 2005

SYNOPSISPheochromocytomas can mimic many unrelated diseases due to their various presenting signs; they are encountered very rarely in childhood. Recently, their neurepsychiatric aspects have become a subject of interest for many workers, but most of the findings reported previously have been observed in adults. We present a case report which is unique in that it concerns a child with pheochromocytoma and psychiatric findings consisting of depression and panic disorder, which were interpreted as being directly related to, since they disappeared after the removal of, the tumor, Depression was persistent and accompanied by a constricting‐type headache, while panic disorder was acute and accompanied by a migraine‐type headache. Another intriguing complication encountered in our case was jaundice; we considered that it could possibly have been due to an adverse effect of catecholamines on hepatocyte function. We conclude that a pheochromocytoma can be confused with neuropsychiatric disorders in children as well as in adults and that it should be considered in the differential diagnosis of such disorders.
A Cluster Analysis of the Multidimensional Pain Inventory
Authors: Walter Laurie , Brannon Linda 
Published: May 2005

SYNOPSISSeventy‐nine patients with chronic headaches of diverse causes, recruited from a headache clinic's biofeedback facility, were administered the Multidimensional Pain Inventory (MPl) for measuring the cognitive, behavioral, and affective dimensions of pain. Using the statistical technique of cluster analysis to organize the results, three clusters emerged, and were similar in their characteristics to those named “Dysfunctional”, “Interpersonally Distressed”, and “Adaptive Coper” by other authors who had applied the Inventory and the cluster analysis technique to other populations (one population containing heterogenous groups of chronic pain patients, and another population of patients suffering from “temporomandibular joint disorders”.)Additional analyses of our results confirmed that the three groups were distinct from one another; and that age, sex, duration of complaint, and diagnosis, were not factors in the formation of the groups.Our results suggest that the MPI is a valid measure of the cognitive, behavioral and affective aspects of pain. Rather than apply a similar intervention program to all headache patients, it might be more effective to tailor treatment to the variations in these aspects exhibited by patients in the three different clusters.
Hemicrania Continua in a Black Patient the Importance of the Non‐Continuous Stage
Authors: Joubert Jacques 
Published: May 2005

SYNOPSISA 52‐year‐old black female for 19 years had severe intermittent unilateral headaches that demonstrated the “clustering12 phenomenon. She was initially diagnosed as having episodic cluster headache. Response to lithium carbonate, ergotamine and courses of corticosteroids was, however, only partial. In December 1989 the headache pattern changed and she developed severe unilateral hemicranial headache that was continuous and non‐remitting. This responded immediately and persistently to oral indomethacin. A diagnosis of hemicraniacontinua (HC) was made.The initial intermittent headache syndrome appears to have been the pre‐continuous stage of hemicrania continua, and not episodic cluster headache as previously supposed. The pre‐continuous phase of hemicrania continua may thus masquerade as episodic cluster headache by reason of its intermittency and “clustering”. In this case, the intermittent stage was protracted. This stage may, conceivably, even be a permanent one. To our knowledge, this is the first report of hemicrania continua in a black African.
Headache in HIV‐1‐Related Disorders
Authors: Lipton R.B. , Feraru E.R. , Weiss G. , Chhabria M. , Harris C. , Aronow H. , Newman L.C. , Solomon S. 
Published: May 2005

SYNOPSISTo define the causes, clinical significance and characteristics of headaches in HIV‐l‐related disorders, we studied 49 consecutive HIV‐1 infected patients who presented with headache. Work‐up included CT scans, cerebrospinal fluid examinations (in the absence of a contraindication) and serologic studies. Overall, 40 of 49 patients (82 percent) had an identifiable serious cause of headache. Cryptococcal meningitis (39 percent) and CNS toxoplasmosis (16 percent) were the leading headache etiologies. Serious causes were more likely in patients diagnosed with AIDS prior to presentation but also occurred in most patients in early stages of infection. Based on this study, we suggest that patients with HIV‐1 infection must be managed with a high index of suspicion when they present with new onset headaches.
The Treatment of Cluster Headache With Repetitive Intravenous Dihydroergotamine
Authors: Mather Paul J. , Silberstein Stephen D. , Schulman Elliott A. , Hopkins Mary McFadden 
Published: May 2005

SYNOPSISWe reviewed our experience with 54 cluster headache patients (23 episodic, 31 chronic) admitted to our headache center 54 tines over the past five years and treated with repetitive intravenous dihydroergotamine (IV DHE).DHE therapy was initiated on admission and prophylactic medication regimens were started or adjusted.All 54 patients had complete relief of their cluster headache, usually within two days. Most (82.8%) had no side effects. The average length of hospitalization was 6.7 days.At the three month followup, 92.9% of the episodic cluster patients were headache‐free and 7.1% had a 50‐74% improvement; at six months, all wore headache‐free.Of the chronic cluster patients, 44.4% wore headache‐free at three months and 52.8% had at least 50% improvement. At six months, 75% were headache‐free and 22.2% wore at least 75% improved, probably as a result of continued prophylactic medication. Repetitive IV DHE safely, rapidly, and effectively controls cluster headache.
The Use of Tinted Glasses in Childhood Migraine
Authors: Good P.A. , Taylor R.H. , Mortimer M.J. 
Published: May 2005

SYNOPSIS20 children with clinically diagnosed migraine were asked to wear either a rose coloured tint or density matched blue tint for a period of 4 months. The frequency, duration and intensity of migraine attacks were recorded, together with the amount of visually provoked beta activity in the EEG. After one month's wear all the children in the study revealed an initial improvement in headache frequency. However, only those children wearing rose tints sustained this improvement up to 4 months, when the mean headache frequency had improved from 6.2 per month to 1.6 per month. The headache frequency of those children wearing blue tints revealed no overall improvement after 4 months. The improvements in headache frequency in children wearing rose tints correlated with a reduction in visually provoked bets activity. Key words: children, migraine, photophobia, tint, visual evoked responses
Inflammatory Alterations in Muscle Contraction Headache
Authors: Nagasawa Arata , Teramoto Jun , Naitou Kazuyuki , Takahashi Akira 
Published: May 2005

SYNOPSISTo investigate the pathophysiology of muscle contraction headache (MCH), several parameters of inflammation were evaluated in 48 patients suffering from MCH, and compared with 50 healthy control subjects: erythrocyte sedimentation rate; C‐reactive protein; white blood cell count; immunoglobulin (Ig) G, A, M; and complement component 3(C3) and C4. Serum C3 and C4 levels were significantly elevated in MCH as compared to control subjects, but the other parameters did not differ significantly. This suggests that the inflammatory process may be involved in the production of MCH.
Disorders in the Lower Cervical Spine. A Cause of Unilateral Headache?
Authors: Michler R.‐P. , Bovim G. , Sjaastad O. 
Published: May 2005

SYNOPSISVarious pathoanatomical disorders may underlie cervicogenic headache.We present a patient who, after 15 years of unilateral headache and neck pain, developed radiating pain in the ipsilateral (left) arm. Cervical myelography demonstrated herniation of the C 6 ‐C 7 intervertebral disc with involvement of the left C 7 ‐root. After decompression of this root, with disappearance of the radiating symptoms, the left‐sided unilateral headache also disappeared. The follow‐up time is 38 months.
Idiopathic Headache as a Possible Risk Factor for Phantom Tooth Pain
Authors: Sicuteri Federigo , Nicolodi Maria , Fusco Bruno Marcello , Orlando Salvatore 
Published: May 2005

SYNOPSISFollowing tooth pulp extirpation, some subjects suffer from persistent pain which affects edentate sitesin absence of any local pathology. As regards this peculiar pain, called phantom tooth pain (PTP), what ispuzzling is the fact there is a low prevalence of PTP in a very large population showing identical conditionsof tooth pulp extirpation. The present investigation indicates that PTP mainly affects migraine (M) andcluster headache (CH) sufferers, whereas it does not affect subjects who have a negative personal andfamily history for idiopathic headache (IH). These results circumscribe the presence of PTP to a specificsection of the population. The present results, besides indicating that PTP may be the result of a peculiarneuronal predisposition relating to IH pathogenesis, suggests some practical therapeutic hints. In fact,successful anti‐ M and anti‐CH prophylactic treatment greatly improve PTP syndrome.
The Medical Management of Trigeminal Neuralgia
Authors: Green Mark W. , Selman Jay E. 
Published: May 2005

SYNOPSISTrigeminal neuralgia results from disturbances in the trigeminal root entry zone which generate repetitiveaction potentials. Drugs which relieve the pain of trigeminal neuralgia depress these potentials.Anticonvulsants which exert this or related effects, and which have been demonstrated to be efficacious intrigeminal neuralgia, include carbamazepine, phenytoin, clonazepam, and valproic acid. Baclofen may act byfacilitating segmental inhibition of the trigeminal complex. The mechanism of action of pimozide for treatingtrigeminal neuralgia is not known.Carbamazepine is suggested as the drag of first choice; baclofen or clonazepam could be added ifcarbamazepine monotherapy is ineffective. When these fail, monotherapy with phenytoin, pimozide, or valproicacid would be a reasonable next step.
Transcranial Doppler (TCD) After Nitroglycerin in Migraine Without Aura
Authors: Zanette Elietta M. , Agnoli Alessandro , Cerbo Rosanna , Chiarotti Flavia , Roberti Cinzia , Buzzi M. Gabriella , Fieschi Cesare 
Published: May 2005

SYNOPSISNitroglycerin, a vasodilating agent, was administered sublingually in migraine without aura patients andin healthy volunteers. Systolic, diastolic and time‐mean flow velocity and pulsatility index, were measuredby transcranial Doppler sonography in the major intracranial arteries before and after nitroglycerinadministration. Following nitroglycerin administration, a significant decrease in systolic and time‐meanvelocity and pulsatility index was observed in migraine patients, whereas in control subjects onlytime‐mean velocity decreased significantly. Based on those findings we hypothesize a more markedresponsiveness to nitroglycerin in migraine patients as compared to healthy subjects.
Treatment of Tension‐type Headache With Tizanidine Hydrochloride: Its Efficacy and Relationship to the Plasma MHPG Concentration
Authors: Shimomura Tokio , Awaki Etsuko , Kowa Hisanori , Takahashi Kazuro 
Published: May 2005

SYNOPSISSeventy‐eight patients with tension‐type headache (TH) were treated with tizanidine hydrochloride(tizanidine). Plasma 3‐methoxy‐4‐hydroxyphenylglycol (MHPG) and serum free fatty acids (FFA) levels in thesepatients were determined before the treatment with tizanidine. Eighteen healthy volunteers composed thecontrol group. Four weeks after the treatment with tizanidine 24 (31%) of 78 patients showed excellentimprovement (excellent group); 28 (35%) showed moderate improvement (moderate group); 18 (23%) showedmild improvement (mild group); 7 (10%) showed no improvement and one (1%) showed worsening of herheadache (no change and worsened group). The plasma MHPG levels in the excellent group were significantlyhigher than in the other groups, including the control group. The serum FFA levels in the excellent group weresignificantly higher than in the controls.In this study, 66% of the patients reported improvement in their headaches. Some patients with TH had highplasma MHPG levels and these patients in particular showed excellent improvement after the administration oftizanidine. Though there may be a placebo response to some extent, the clinical usefulness of tizanidine for THseems to be excellent. Further study is necessary concerning the pharmacological effect of tizanidine andplasma MHPG levels in patients with TH.
Long‐Term Effects of Biofeedback on Migraine Headache: A Prospective Follow‐Up Study
Authors: Gauthier Janel G. , Carrier Sylvie 
Published: May 2005

SYNOPSISThe aim of the present study was two‐fold: to assess the long‐term effects of biofeedback on migraine, andto determine the extent to which additional treatment after biofeedback treatment is completed can affectfollow‐up results. Ninety‐six women whose migraine had been treated through biofeedback either 2–3 years(shorter follow‐up) or 6–7 years (longer follow‐up) earlier were divided into four groups according to how longago they had received their biofeedback treatment and whether or not they had received any additionaltreatment (whatever the nature) since the posttreatment assessment: shorter follow‐up without additionaltreatment (n = 24), shorter follow‐up with additional treatment (n = 22), longer follow‐up without additionaltreatment (n = 24), and longer follow‐up with additional treatment (n = 26). Subjects were asked to keep aheadache diary for five weeks, as they had done during earlier assessments, Overall, results showed thatmigraine activity was significantly less at follow‐up than at pretreatment. However, whether the observedlong‐term benefits could be attributed to biofeedback was unclear because medication was found to be asmuch in use at follow‐up as at pretreatment. Results also indicated that 51% of the subjects did seek additionaltreatment between posttreatment and follow‐up. Contrary to expectations, however, additional treatment wasnot associated with better therapeutic benefits at follow‐up. The research and the clinical implications of thosefindings are discussed.
Flunarizine in Migraine Prophylaxis: An Indian Trial
Authors: Thomas M. , Behari M. , Ahuja GK 
Published: May 2005

SYNOPSISFlunarizine, a calcium channel blocker is considered useful in migraine prophylaxis. We report the first Indian trial with thisdrug. Fifteen patients with migraine were studied in a 6 months double‐blind, placebo‐controlled crossover trial. Flunarizinewas superior to placebo in reducing the severity and duration of the individual attacks though there was no statisticallysignificant effect on frequency of migraine attacks. The side effects most frequently caused by flunarizine were weight gainand daytime sleepiness.
A Tape‐Recorded Test of Hypnotic Susceptibility for Screening Headache Patients: A Feasibility Study of the Harvard Group Scale of Hypnotic Susceptibility, Form A
Authors: Primavera Joseph P. , Patterson Stephanie 
Published: May 2005

SYNOPSISA study to examine the feasibility of using the Harvard Group Scale of Hypnotic Susceptibility, Form A (HGSHS)as a screening instrument was undertaken at an inpatient headache treatment program. Nine patients diagnosedwith chronic daily headache and drug rebound were administered the HGSHS. Analysis of the results showed nosignificant difference in hypnotic susceptibility when headache patients were compared to a control group. Aftertaking the HGSHS, three of the five subjects who had headache at the time of testing reported a 25% reduction inpain, one was unchanged, and one reported a 13% increase in pain. The results obtained did notsuggest acorrelation between level of hypnotic susceptibility and reduction of headache.
The Hospital Management of Severe Migrainous Headache
Authors: Jauslin P. , Goadsby P.J. , Lance J.W. 
Published: May 2005

SYNOPSISIn a two year period, 47 patients with migraine were hospitalized for the management of severe headache; 18 had acute migraine (duration less than 72 hours), 17 had status migrainosus (duration by definition more than 72 hours), and 12 had chronic daily headaches qualitatively of a migraine type. Treatment in all comprised cessation of all previous medication, plus one of the following: intravenous DHE, intravenous lidocaine, a combination of lidocaine + DHE, or subcutaneous sumatriptan. Improvement from DHE, lidocaine, or both was slow and often incomplete. Sumatriptan was not used in patients with chronic daily headaches; in the 8 cases of acute migraine or status migrainosus in which it was used, improvement was rapid and complete in seven.
“Symptomatic Migraine”: Intracranial Lesions Mimicking Migrainous Headache ‐A Report of Three Cases
Authors: Schlake H.‐P. , Grotemeyer K.‐H. , Husstedt I. W. , Schuierer G. , Brune G. G. 
Published: May 2005

SYNOPSISCase reports of three headache patients, two with intracerebral meningioma and one with hydrocephalus are presented, in whom the clinical picture fulfilled the criteria of the International Headache Society (IHS) for the diagnosis of migraine. The symptomatic (ie, lesional) nature of the headaches could be detected by neither clinical neurological examination nor routine investigations such as EEG and skull x‐ray, On the other hand, brain imaging techniques (CT, MRI) were found to be of particular in value diagnosing the lesions. Our cases indicate that neuroimaging with CT or MRI in the assessment of headache patients should not be handled too restrictively. Compared to CT, however, the additional diagnostic value of MRI in headache seems to be limited.