bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of Fertilizers with Urease wnd Nitrification Inhibitors on Durum Wheat Crop on Yield and Quality (Triticum turgidum L. subsp. durum)
Authors: FOLINA Antigolena , KAKABOUKI Ioanna , ROUSSIS Ioannis , MAVROEIDIS Antonis , KARYDOGIANNI Stella , KOYNELI Varvara , EFTHIMIADOU Aspasia , KATSENIOS Nikolaos , TSOUKANAS Vasilis , BILALIS Dimitrios 
Published: February 2024

Conventional agricultural has a significant role in climate change. For this reason, farmers choose more innovative practices such as fertilizers inhibitors. Durum wheat (Triticum turgidum L. subsp. durum) is the most cultivated winter crop in the Mediterranean basin. The scope of this study is to determine the improvement of the fertilizer yield by adding nitrification (DMPSA) and urease (NBPT) inhibitor in urea in durum wheat crop. Meridiano variety was evaluated for one growing period through 2019–2020 under two basic fertilization (20-20-0 and 12-40-0 (+10S +Zn). The experiments were designed according to split-plot design, 2 main plots (basic fertilization) and 7 subplots (top fertilization). The top fertilization were the various urea combination treatments (urea, urea + urease inhibitor thiophosphoric-triamide (NBPT) (UI), urea + nitrogen inhibitor 3,4- dimethylpyrazole succinic (DMPSA) and control. Nitrogen markers, such as nitrogen use efficiency (NUE), nitrogen harvest index and nitrogen agronomic efficiency (NAE) were used to evaluate nitrogen release. The length of the inflorescences was over 20 cm for all fertilizations. Regarding basic fertilization, larger inflorescences were recorded with 12-40-0 (+10S +Zn). The grain protein content and nitrogen were higher by 1-2% under basic basic fertilization 20-20-0. Grain and biomass production were increased with both fertilizers’ inhibitors (NBPT and DMPSA). Between two inhibitors, urease inhibitor (NBPT) yielded higher than DMPSA.
The official presentation to science of a new species of Hechtia (Bromeliaceae: Hechtioideae) from the Pacific Lowlands in Mexico
Authors: Ramírez-Morillo Ivón , Ramírez-Diaz Claudia J. , Magaña Rueda Patricia , Tapia-Muñoz José Luis , Rivera Martínez Ricardo 
Published: February 2024

Background: Hechtia is characterized by its terrestrial, succulent rosettes, dioecy, and unisexual, dimorphic flowers, mainly fragrant. The paucity and fragmentary herbarium material limit the species recognition but living material reveals diagnostic characters to delimitate them.
Hypothesis: Hechtia species are circumscribed by a combination of vegetative and floral characters of both sexes. If the new taxon does not share morphological characters with other species, it will be described as new.
Taxon: Hechtia.
Study site and dates: Chamela-Cuixmala Biosphere Reserve, Jalisco, 1985-2023.
Methods: Field collected, cultivated as well as herbarium material of the new taxon were analyzed and compared to other species from the Pacific Lowlands and adjacent areas, particularly flowers of both sexes, fruits, and seeds. Conservation status using IUCN criteria is reported for the new species.
Results: Specimens of Hechtia chamelensis have been misidentified as H. laevis and H. reticulata (both described from fruiting, fragmentary specimens) but the fruit and seed features of both taxa do not match those of the new species. H. chamelensis is known from the Chamela-Cuixmala Biosphere Reserve and it is characterized by strict sympodial growth pattern, green leaves with red hues, shiny and glabrous above, white lepidote below, panicles usually simple to (rarely staminate ones) 2-divided, staminate flowers pinkish to pale white, pistillate with pale green to white petals.
Conclusions: Vegetative and reproductive features as well as geographical distribution allow the recognition of H. chamelensis as a new species native from Jalisco, Mexico.
The “Red Tourism” as an Instrument of the Historical Policy of Modern China
Authors: Kuzmin Kirill 
Published: February 2024

This article is devoted to the consideration of “red tourism” as an instrument of Chinese historical policy. The author analyzes the phenomenon of Chinese “red tourism”, which was launched in 2004, and under Xi Jinping turned into an instrument of ideological and patriotic education of people. “Red tourism” appeared only in the beginning. In the 2000s, however, its prehistory dates back to the 1950s and 1960s. In the 1990s, programs of patriotic education of young people were launched, which took place at important historical sites associated with the events of the first half of the twentieth century. This became the foundation for the emergence of “red tourism”. Full-scale development of the direction aimed at ideological education, economic income and development of the country's regions began after 2012. By 2019, the number of visits to places of «red tourism» has grown to 1.4 billion. Its routes provide an opportunity for Chinese citizens to get acquainted with the events of China's history, which are associated with the formation of the CPC, the civil and Sino-Japanese wars, the formation of the PRC. “Red tourism” takes place in the places of military glory and historical events of the CPC and the country (Beijing, Shaoshan, Shanghai, Yan'an, Ruijin, etc.), which gives travelers the opportunity to “touch” history. This direction is funded and supported by the party and the state, brings serious profits, gives impetus to the development of the related areas of China and is one of the popular destinations of domestic tourism. The author comes to the conclusion that the focus of “red tourism” on history and the connection with the collective memory of the past make it an instrument of the historical policy of modern China.
Szlachta województwa krakowskiego wobec konfliktów wyznaniowych i problemu tolerancji religijnej w Rzeczypospolitej w latach 1572-1648
Authors: Kozyrski Robert 
Published: February 2024

Artykuł prezentuje stanowisko szlachty województwa krakowskiego wobec występujących w Rzeczypospolitej problemów i konfliktów religijnych. Podstawę tych rozważań stanowią akta sejmiku w Proszowicach, korespondencja urzędowa funkcjonariuszy świeckich i duchownych państwa polsko-litewskiego oraz relacje naocznych świadków zdarzeń, głównie w Krakowie. Do najważniejszych zagadnień w nim poruszonych, które absorbowały uwagę szlachty, należało funkcjonowanie uchwalonej w 1573 r. konfederacji warszawskiej oraz wynikające z niej gwarancje swobód religijnych i politycznych. W sferze jej zainteresowań znajdowały się również Kościoły różnych wyznań, przede wszystkim zaś problemy kalwinistów i luteran. W mniejszym stopniu uwaga sejmikujących skupiała się na konfliktach pomiędzy prawosławnymi a unitami oraz na kwestii prześladowania braci polskich (arian). Wiele miejsca poświęcono też dyskusjom nad wypracowaniem mechanizmów prawnych, które miały ograniczać występowanie tumultów religijnych w miastach Rzeczypospolitej.
TERAPI TASAWUF SEBAGAI UPAYA PENANGGULANGAN STRESS, DEPRESI, DAN KECEMASAN
Authors: Muslimin Muslimin 
Published: February 2024

Salah satu bentuk stres yang dapat menimbulkan gangguan kejiwaan kecuali kecemasan (ansietas) adalah juga yang dinamakan depresi. Baik kecemasan maupun depresi kedua-duanya mempunyai gejala-gejala gangguan fungsi dari organ-organ tubuh yang dipersarafi oleh sistem saraf otonom (misalnya, pernafasan, peredaran darah, pencernaan, seksual, dan lain sebagainya). Gejala fisik maupun psikis (kecemasan dan depresi) seringkali tumpang tindih, tidak ada suatu batasan yang jelas, sehingga seseorang yang mengalami stres dapat diartikan bahwa orang itu memperlihatkan berbagai keluhan-keluhan fisik, kecemasan, dan juga depresi.
Dalam mengatasi stres, depresi, dan kecemasan seyogyanya selain terapi holistik- para psikiater dapat menggunakan terapi keagamaan, dalam hal ini bisa juga dengan terapi tasawuf. Relevansi tasawuf secara seimbang memberikan kesejukan batin dan disiplin syariah sekaligus. Ia bisa dipahami sebagai pembentuk tingkah laku melalui pendekatan tasawuf suluky, dan bisa memuaskan dahaga intelektual melalui pendekatan tasawuf falsafi. Ia bisa diamalkan oleh setiap muslim, dari lapisan sosial manapun dan tempat manapun. Secara fisik mereka menghadap satu arah, yaitu Ka’bah dan secara ruhaniah mereka berlomba-lomba menempuh jalan tarekat melewati ahwal dan maqam menuju kepada Tuhan yang satu Allah SWT.
ASOSIASI KONINKLIJKE JAVA MOTOR CLUB TAHUN 1908-1941
Authors: Elita Karina Sandra 
Published: February 2024

This research discusses the association of Koninklijke Java Motor Club from 1908 to 1941. The basis of the theory used is organizational theory. The issue studied is (1) How the development of membership and the composition of membership of the Koninklijke Java Motor Club association in the Dutch East Indies, (2) What activities the Koninklijke Java Motor Club association conducted in the Dutch East Indies in 1908 to 1942, (3) How the Koninklijke Java Motor Club association cooperated with other associations both in the Dutch East Indies and outside the Dutch East Indies. The results showed that the Koninklijke Java Motor Club is a society of people who own motor vehicles (either cars or motorcycles) in the Dutch East Indies, this association belongs to the Kingdom of the Netherlands.The development of the number of members of the Koninklijke Java Motor Club from 1908 to 1941 showed fluctuating, this was due to the malaise crisis in 1930. Initially, Koninklijke Java Motor Club activities only in Java Island then developed in Sumatra, Bali, and Sulawesi.With the widespread activities of Koninklijke Java Motor Club outside Java Island decided to change the name of the association to Koninklijke Nederlandsch Indie Motor Club in December 1932. It can be concluded that Koninklijke Nederlandsch Indie Motor Club is an association oriented towards the hobbies and tourism activities of the Dutch East Indies.
Keywords: Koninklijke Java Motor Club; Dutch East Indies; Association; Koninklijke Nederlandsch Indie Motor-Club
AOA Critical Issues: The Status of the Vice Chair Position in Orthopaedic Surgery Departments in 2023
Authors: Goldfarb Charles A. , Salazar Dane H. 
Published: February 2024

Abstract:
The vice chair position in orthopaedic surgery departments has become increasingly prevalent over the last 10 years. Prior to this development, there were few, if any, vice chairs to support the chairperson position. The vice chair role has increased in importance as a result of increasing practice size and the increasing complexity of the health-care environment. The goal of this review was to summarize the current status of the vice chair position within orthopaedic surgery departments and to share the variety of vice chair roles that exist today.
An Automated Wavelet Scattering Network Classification Using Three Stages of Cataract Disease
Authors: Al-Saadi Enas Hamood , Khdiar Ahmed Nidhal , Al-Saadi Lamis Hamood 
Published: February 2024

إعتام عدسة العين وهو مرض يصيب العين حيث يسبب تشوهًا بصريًا ويمكن أن تؤدي المرحلة المتأخرة من هذا المرض إلى العمى. ويعتبر مرضًا صامتًا يمكن أن يحدث دون ظهور الأعراض. لذلك ، فإن الطريقة الأكثر فاعلية للكشف عن إعتام عدسة العين هي من خلال الكشف الدقيق في الوقت المناسب لمنع الأذى والعمى والعمليات المكلفة. ان الغرض من هذه البحث هو اقتراح نظام آلي يعتمد على شبكة نثر المويجات التي تصنف المرضى إلى أربع فئات: إعتام عدسة العين المبكر وإعتام عدسة العين المتوسط وإعتام عدسة العين المتأخر وعدم إعتام عدسة العين باستخدام 512 صورة لقاعدة البيانات ODIR (212 شخص مصاب و300 شخص غير مصاب). الخطوة الأولى في هذه التقنية هي خطوة المعالجة المسبقة لصورة الشبكية التي كانت عبارة عن مرشح المتوسط ، والذي تم استخدامه لتقليل ضوضاء الصورة. ثم بعد ذلك استخدام طريقة معادلة الرسم البياني التكيفية محدودة التباين (CLAHE) لتحسين مستوى عينات الصورة. بعد ذلك ، يمكن استخراج الخصائص منخفضة التباين من بيانات الصورة باستخدام شبكة تشتت المويجات لاستخدامها في تطبيقات التعلم العميق. في هذه الشبكة ، يتم استخدام مرشحات تحجيم تمرير منخفض وموجات موجية محددة مسبقًا. كان متوسط دقة الطريقة المقترحة 100٪ لأربع فئات (غير مصاب، مبكر، متوسط، شديد). علما ان النتائج موعودة مقارنة مع أعمال أخرى مماثلة.
Isolation and Identification of Flavonoid Compounds from Euphorbia Milii Plant Cultivated in Iraq and Evaluation of its Genetic Effects on Two Types of Cancer Cell Line
Authors: Salman Z. O. , Alwash Bushra M.J. , Kadhim E. J. 
Published: February 2024

يعتبر "تاج الأشواك" أو نبات شوكة المسيح، وهو من نباتات الزينة الطبية ، ينتمي إلى جنس يوفوربيا. E. milii يحتوي كميات وفيرة من المركبات الفينولية ، التربينات، الستيرويدات والقلويدات. كانت الأهداف الرئيسية لهذه الدراسة هي فحص مستخلصات الفلافونويد والنانو فلافونويد ضد نوعين من خطوط الخلايا السرطانية. تم تصنيع مركبات الفلافونويد النانوية عن طريق تفاعل مركب الكيتوسان والماليك اسد. تم تحليل مركبات الفلافونويد النانوية بواسطة مقياس الطيف الضوئي UV-sp -8001 بطول موجي 200-1000 نانومتر ، تم استخدام المجهر الإلكتروني (TEM) والمجهري الإلكتروني الماسح(SEM) لتحديد الخصائص المورفولوجية لمركبات الفلافونويد النانوية. يعتبر الفلافونويد والنانوفلافونويدعقار قوي ومتطور ضد خلايا سرطان الثدي (MCF-7) وخلايا سرطان البروستات(PC3) . تم فحص الفعالية المضادة للسرطان من مركبات الفلافونويد والنانوفلافونويد على خطين مختلفين من الخلايا السرطانية وكذلك خطوط الخلايا السليمة باستخدام اختبار MTT. تم استخدام تجزئة الحمض النووي وتقنية تلوين الخلايا بالصبغة المزدوجة AO / EtBr لفحص علامات موت الخلايا المبرمج. لتحديد تشتت دورة الخلية ، تم استخدام قياس التدفق الخلوي ، وأظهرت النتائج أن كميات الفلافونويد والنانوفلافونويد لها نشاطا ساما وفعالا ضد خطوط خلايا سرطان الثدي والبروستات. بالإضافة إلى ذلك ، تم ربط إيقاف دورة الخلية في مرحلة G0 / G1 بموت الخلايا المبرمج لخطوط الخلايا التي يسببها الفلافونويد والنانوفلافونويد. وفقًا لهذه النتائج ، تمنع مركبات الفلافونويد والنانوفلافونويد من تكاثر خطوط الخلايا السرطانية ، مما يؤدي إلى توقف دورة الخلية وتحفيز موت الخلايا المبرمج. تشير النتائج المتاحة إلى أن مركب الفلافونويد والنانوفلافونويد سيمثل نهجًا علاجيًا واعدًا لعلاج الخلايا السرطانية من الأنواع الأخرى.
A Machine Learning Approach for Predicting Stunting in Under Five Children: The Case of Pakistan Demographic and Health Survey
Authors: Asad Muhammad , Zouq Aqsa 
Published: February 2024

Abstract
Stunting in children less than five years of age is widely recognized as a major health problem in most of the developing countries of the world including Pakistan. It is considered as one of the contributing factors of death and multiple diseases. Pakistan has been reported to have one of the highest levels of prevalence of child malnutrition as compared to other developing countries as four out of ten children are stunted. Studies regarding prediction of nutrition status of children and identification of factors that lead to stunting have the potential to reveal great insights in the domain of healthcare informatics. This study identifies stunting in under-five children and also finds the association of demographics, socioeconomic and maternal characteristics that leads to stunting. The study is validated using nutrition-related attributes from Pakistan Demographic and Health Survey dataset. Machine learning based data driven model is trained to classify a child as normal or stunted. Results reveal that out of the selected attributes residence, wealth index, mother’s education, child’s age, and height are strong predictors of stunting. Results also show that the model can be used to predict various nutrition related problems in children using the survey dataset. The analysis of several evaluation metrics concludes that among four classifiers SVM outperforms with an average accuracy of 98.5%.
WITHDRAWN: Understanding the signalling pathway of the GnRH receptor: a molecular dynamics study
Authors: Paspali Elpiniki , Kubiak-Ossowska Karina , Ferro Valerie Anne , Mulheran Paul Alexander 
Published: February 2024

Abstract
The full text of this preprint has been withdrawn by the authors since they no longer stand by the findings/conclusions of this work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author.
Highest informative density of a TIN model
Authors: Nevalainen Paavo Tapani , Virjonen Petra , Salmivaara Aura , Holmström Eero , Heikkonen Jukka 
Published: February 2024

Abstract

A point cloud (PC) source is useful for micro-topography, if the shortest spatial wavelength it carries is enough for a particular registration task. This wavelengthvaries a lot due to different scanning methodologies and environmentalconditions. We propose an automated procedure for approximating the highest meaningful density of a PC in order to produce relatively noiseless ground models.This density limit can serve as a set target for existing thinningprocedures of large PC archives. Three methods to approximate the highest meaningful density are being compared:mean absolute error (MAE) of the triangulated irregular network (TIN) fit, minimum description length (MDL) and direct spatial wavelength registration (DWR). Each method is computationally expensive but can be subjected to a small set of local samples of a possibly large PC archive. Natural data samples were: a photogrammetric PC and a detail of it,and an aerial laser scan (ALS), all from the same forest site. The pipeline for finding a suggested minimum PC density has n log n complexity in terms of original PC size n. DWR found a wavelength range 5 ... 14 m from a synthetic case with the wavelength of 13 m. All methods give mean TIN edge length0.05 ... 0.1 m corresponding well with a published choice 0.2 m.
Hepatic sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) primary prophylaxis in patients undergoing hematopoietic stem cell transplantation: a network meta-analysis of randomized clinical trials
Authors: Sousa-Pimenta Mário , Martins Ângelo , Vaz Carlos Pinho , Leite Luís , Mariz José 
Published: February 2024

Abstract
Introduction: Hepatic sinusoidal obstruction syndrome/veno-occlusive disease (SOS/VOD) is a major complication following hematopoietic stem cell transplantation, resulting from immune and chemical toxicity to the sinusoidal endothelium and hepatocellular damage. In most severe cases, multiorgan dysfunction occurs, so it is essential to promptly identify patients at greater risk of SOS/VOD and to adopt prophylactic strategies.

Objectives: This study aims to systematize the impact of different approaches as primary prophylaxis of SOS/VOD in patients undergoing hematopoietic stem cell transplantation (HSCT).

Methods: A systematic review and meta-analysis of randomized clinical trials evaluating different strategies for primary prophylaxis of SOS/VOD was carried out in a pairwise fashion and with a consistent network structure. The odds ratio (OR) and corresponding confidence intervals were calculated using the random-effects model. Heterogeneity was assessed by the I2 method and the efficacy of each approach was estimated by SUCRA (surface under the cumulative ranking curve).

Results: Considering all patients undergoing HSCT, ursodeoxycholic acid (UDCA) [OR=0.38, 95%CI 0.14-1.06, SUCRA=0.720] was associated with a lower incidence of VOD while defibrotide reached a modest reduction in its incidence [OR=0.64, 95%CI 0.23-1.67; SUCRA=0.486]. Considering the subgroup of patients undergoing hematopoietic progenitors allotransplantation, defibrotide scored higher [OR=0.51, 95%CI 0.09-2.85, SUCRA=0.650], by comparison with UDCA [OR=0.53, 95%CI 0.14-1.96, SUCRA=0.639].

Conclusion: This is the first meta-analysis comparing primary prophylaxis of SOS/VOD. UDCA yielded more promising results when considering all patients undergoing hematopoietic stem cell transplantation, although, in a subgroup analysis of the ones exposed to allogeneic grafts, it becomes not significantly overrun by defibrotide.
Group-based versus individual-based exercise therapy in patients with knee osteoarthritis: study protocol for a non-inferiority randomized controlled trial
Authors: Lopes Clécio Lima , Lopes Amanda Virgínia Souza Lima , Azevedo Rebeca Cajueiro , de Souza Francis Trombini , Silva Tarcisio Fulgêncio Alves da 
Published: February 2024

Abstract

Background
Knee osteoarthritis (KOA) is one of the most prevalent health issues, affecting approximately 67% of women over 60 years old. Clinical guidelines recommend individualized muscle training to treat this condition. However, a lack of human and financial resources hinders the delivery of this treatment. In response to this limitation, group training may be an alternative. Nevertheless, there are no studies aiming to compare the effectiveness of group training to individual training. Therefore, this study aims to compare the non-inferiority of a group-delivered muscle training program to the same individually delivered training in clinical and functional aspects in elderly women with KOA.
Methods
This is a randomized controlled non-inferiority trial with two arms, parallel groups, blinded evaluator, conducted in Petrolina - PE, evaluating women aged 60 or older. Participants randomly assigned will undergo an eight-week training, either in individual sessions (Control Group - IB) or as part of a group (Intervention Group - GB) of four participants, supervised by a physical therapist. Blind assessments at baseline, immediately post-intervention, and four weeks post-intervention will include feasibility, safety, and satisfaction analysis of the training program; pain; quality of life; and physical function. Data will be analyzed using the Statistical Package for Social Sciences (SPSS) version 22. Estimated marginal means of each clinical and functional outcome for both groups (IB and GB) will be compared using mixed-effects generalized linear models. The primary analysis will test our main hypothesis that group training is non-inferior to individualized training regarding the primary outcome: relative reduction (%) in the WOMAC questionnaire pain subscale. Confidence intervals of 95% will be calculated. A significance level of p < 0.05 will be adopted in all analyses.
Discussion
Expected results suggest that a group-based approach is not inferior to an individual one in this population.
Trial registration; Brazilian Registry of Clinical Trials (ReBEC) ID: RBR-5bq9jh3. Registered on 18 August 2023. Link: http://www.ensaiosclinicos.gov.br; Universal Trial Number (UTN) of World Health Organization: U1111-1289-2580.
LILRB4 regulates multiple myeloma development through STAT3-PFKFB1 pathway
Authors: Zheng Jun-Ke , Xie Li , Chen Chiqi , Zhang Tinghua , Yang Wenqian , Zheng Denghao , Cao Liyuan , Yuan Jin , Xu Yilu , Zhang Yaping , Liu Ligen , Liang Aibin , Yu Zhuo 
Published: February 2024

Abstract

Although multiple myeloma (MM) responds well to immunotherapeutic treatment, certain portions of MM are still unresponsive or relapse after immunotherapy. Other immune molecules are needed for the immunotherapy of MM. Here, we revealed that leukocyte immunoglobulin-like receptor B4 (LILRB4) was highly expressed in multiple myeloma cell lines and patient samples and that the expression of LILRB4 was adversely correlated with the overall survival of MM patients. Knockdown of LILRB4 efficiently delayed the growth of MM cells both in vitro and in vivo. Mechanistically, IKZF1 transactivated LILRB4 expression to trigger the downstream of STAT3-PFKFB1 pathways to support MM cell proliferation. Blockade of LILRB4 signaling by functional antibodies can effectively inhibit MM progression. Our data show that targeting LILRB4 is potentially an additional therapeutic strategy for the immunotherapeutic treatment of MM.