bluuebunny/crossref_metadata_2025_split huggingface dataset:
Design consideration on integration of mechanical intravascular ultrasound and electromagnetic tracking sensor for intravascular reconstruction
Authors: Cai Wenran , Hara Kazuaki , Tomii Naoki , Kobayashi Etsuko , Ohya Takashi , Sakuma Ichiro 
Published: January 2024

Abstract
Purpose
Considering vessel deformation, endovascular navigation requires intraoperative geometric information. Mechanical intravascular ultrasound (IVUS) with an electromagnetic (EM) sensor can be used to reconstruct blood vessels with thin diameter. However, the integration design should be evaluated based on the factors affecting the reconstruction error.

Methods
The interference between the mechanical IVUS and EM sensor was measured in different relative positions. Two designs of the integrated catheter were evaluated by measuring the reconstruction errors using a rigid vascular phantom.

Results
When the distance from the EM sensor to the field generator was 75 mm, the interference from mechanical IVUS to an EM sensor was negligible, with position and rotation errors less than 0.1 mm and 0.6°, respectively. The reconstructed vessel model for proximal IVUS transducer had a smooth surface but an inaccurate shape at large curvature of the vascular phantom. When the distance to the field generator was 175 mm, the error increased significantly.

Conclusion
Placing the IVUS transducer on the proximal side of the EM sensor is superior in terms of interference reduction but inferior in terms of mechanical stability compared to a distal transducer. The distal side is preferred due to better mechanical stability during catheter manipulation at larger curvature. With this configuration, surface reconstruction errors less than 1.7 mm (with RMS 0.57 mm) were achieved when the distance to the field generator was less than 175 mm.
Formation of glycidol fatty acid esters and 3-monochloro-1,2-propanediol fatty acid esters in heated foods
Authors: Shimamura Yuko , Miyazaki Megumi , Sawaki Shiho , Inagaki Ryo , Honda Hiroshi , Masuda Shuichi 
Published: January 2024

AbstractGlycidol fatty acid esters (GEs) and 3-monochloro-1,2-propanediol fatty acid esters (3-MCPDEs) are formed at high temperatures during edible oil production. In this study, ground meat (beef, pork, and chicken) patties, cookies, and cupcakes were heated under various conditions using a temperature-controlled device to determine the amount of GEs and 3-MCPDEs produced. GE and 3-MCPDE were not detected in any meat heated in the oven (250 °C). When heating all meats using a muffle furnace, GEs were not detected at 400 °C but they were detected at 500 °C and 600 °C. At 600 °C, 3-MCPDEs were detected in all meats. When cookie and cupcake doughs prepared with rapeseed oil were heated in the oven, GEs were formed in both samples, reaching a maximum at 210 °C. 3-MCPDEs were detected only in cookies, reaching its maximum at 250 °C. The percentage of each GE in heated cookies and cupcakes was related to the fatty acid composition of the rapeseed oil. These results suggest that the formation of GEs and 3-MCPDEs may be affected by food ingredients, cooking device, and heating time, as well as heating temperature.
Development of a master–slave 3D printed robotic surgical finger with haptic feedback
Authors: Hamdi Jamal T. , Munshi Shadi , Azam Sufyan , Omer Aiman 
Published: January 2024

AbstractRobotic surgery started nearly 30 years ago. It has achieved telepresence and the performance of repetitive, precise, and accurate tasks. The “master–slave” robotic system allows control of manipulators by surgeon at distant site. Robotic surgical fingers were developed to allow surgeons to move them with accuracy through sensors fixed on surgeon’s hand. Also, haptic sensors were developed to allow transmission of sensation from robotic finger to surgeon’s finger. A complete system of a, 3D printed by a stereolithography (SLA) 3D printer, robotic surgical finger with haptic feedback system is proposed. The developed system includes a master glove that controls the motion of a 3DOF robotic slave finger while getting haptic feedback of force/pressure exerted on it. The precise control of the slave robotic finger was achieved by applying a Proportional Integral and Derivative (PID), fast and robust, control algorithm using an Arduino based hardware and software module. The individual joint angles, metacarpophalangeal joint (MCP) and proximal interphalangeal joint (PIP), and wrist were measured using rotatory and inertial sensors respectively. The degree of movement for MCP, PIP, and Wrist joints were measured to be 0–86°, 0–71°, and 0–89° respectively. Motion to the robotic finger is mimicked by a glove motion requiring minimal learning curve for the device. The collected data for the slave motion is in good agreement with the master-glove motion data. The vibro-tactile haptic feedback system was developed to distinguish between three different materials to mimic human flesh, tumor, and bone. The master–slave system using robotic surgical finger with good simultaneous movement to surgeon’s finger and good haptic sensation will provide the surgeon with the opportunity to perform finger dissection in laparoscopic and robotic surgery, as it used to be in open surgery. 3D bio printing will make this process even cheaper with the added advantage of making surgical tools locally according to the need of the surgery. An ongoing work is to develop silicone based 8 mm robotic surgical finger with multiple type haptic feedback.
Control concept for the regulation of the surface layer properties using consecutive cuts in cryogenic hard turning of AISI 52100
Authors: Grossmann Felix , Follmann Viktor , Zhu Tong , Uebel Julian , Wolke Stefan , Kirsch Benjamin , Smaga Marek , Seewig Jörg , Beck Tilmann , Aurich Jan C. 
Published: January 2024

AbstractIn this study, a control concept for the simultaneous adjustment of the workpiece residual stresses and the surface roughness when cryogenic hard turning AISI 52100 is presented. The turning process is comprised by two consecutive cuts in which the process parameters vary, focusing on roughing and finishing; i.e. first a high, then a low depth of cut. On the first cut, the surface residual stress is adjusted via the cutting speed. On the second cut, the surface roughness is minimized by adjusting the feed rate while maintaining high compressive residual stresses. The surface residual stresses are determined by XRD and hole drilling measurements. For the estimation of the residual stresses the passive force is used. Based on these results, a control concept is presented which makes several assumptions that are partly validated by experiments.
Forecasting EUA futures volatility with geopolitical risk: evidence from GARCH-MIDAS models
Authors: Lu Hengzhen , Gao Qiujin , Xiao Ling , Dhesi Gurjeet 
Published: January 2024

AbstractThis paper examines whether the information contained in geopolitical risk (GPR) can improve the forecasting power of price volatility for carbon futures traded in the EU Emission Trading System. We employ the GARCH-MIDAS model and its extended forms to estimate and forecast the price volatility of carbon futures using the most informative GPR indicators. The models are examined for both statistical and economic significance. According to the results of the Model Confidence Set tests for the full-sample and sub-sample data, we find that the extended model, which accounts for the threat of geopolitical risk, exhibits superior forecasting ability for the full-sample data, while the model that includes drastic changes in geopolitical risk in Phase II and the model that considers serious geopolitical risk in Phase III have the best predictive power. Moreover, all GPR-related variables we use contribute to increasing economic gains. In particular, the threat of geopolitical risk contains valuable information for future EUA futures volatility and can provide the highest economic gains. Therefore, carbon market investors and policymakers should pay great attention to geopolitical risk, especially its threat, in risk and portfolio management.
Hypnosis for Symptom Management in Adult Cancer Patients: What is the Evidence?
Authors: Vayne-Bossert Petra 
Published: January 2024

Opinion StatementAs a palliative care specialist and a hypnotherapist, I use therapeutic communication and conversational hypnosis daily in my patient – doctor relationship. Formal hypnotherapy sessions are integrated in my practice whenever patients are open or wish for such an approach in relation to a specific symptom, for better overall management of their disease burden and/or enhanced well-being. Although hypnosis has been used for centuries in medical practice and for thousands of years in healing practices in ancient cultures all over the world, the evidence remains scarce. Nevertheless, in the last 10 years several randomised controlled trials have been conducted, building up an evidence base. In contrast to most oncological treatments, hypnotherapy is far from being considered evidence-based “standard care”. It is however, if practiced by a trained health care professional, almost free of side effects and therefore potentially has a very favourable benefit-to-harm ratio. The question arises whether hypnotherapy will ever become a standard of care intervention? This seems unlikely since its efficacy may be influenced by the patient’s belief in hypnosis and compliance to therapy. Furthermore, a fundamental necessity is a personalised approach that moves hypnotherapy more into the category of individual-centred care rather than standard care.
Spontaneous Coronary Artery Dissection (SCAD) from an Interventionalist Perspective
Authors: Brunton Nichole , Best Patricia J. M. , Skelding Kimberly A. , Cendrowski Emily E. 
Published: January 2024

Abstract
Purpose of Review
Spontaneous coronary artery dissection (SCAD) is an increasingly recognized cause of acute coronary syndrome (ACS), particularly among women < 50 years of age. Here, we aim to review the pathogenesis of SCAD, discuss SCAD as an initial manifestation of systemic arterial disease, and highlight invasive strategies as well as unique challenges in the care of women with SCAD.

Recent Findings
A paradigm shift has occurred in the care of SCAD patients in the past decade as recommendations for conservative management have become widespread. Invasive interventions are reserved for patients with hemodynamic compromise or active ischemia due to increased periprocedural complications and failure rates. Certain patient populations have been identified for larger territory infarcts and proximal disease including patients with known connective tissue disease, premenopausal women, and patients with pregnancy-associated SCAD (P-SCAD).

Summary
Current recommended management of SCAD is conservative. Despite a growing awareness of SCAD and its known association with systemic arteriopathies in women, evidence-based data remains scarce. Future studies focused on identifying genetic factors, optimal medical therapy after SCAD, and techniques to minimize interventional complications are needed.
Resilience Training Programs with Police Forces: A Systematic Review
Authors: Moreno Ana F. , Karanika-Murray Maria , Batista Patrícia , Hill Rowena , Vilalta Susanna Rubiol , Oliveira-Silva Patrícia 
Published: January 2024

AbstractThrough the course of their career, it is expected that police officers are exposed to stressful and emotionally challenging environments, which, combined with well-known organizational and occupational stressors, makes this professional class vulnerable to several psychological and medical conditions. In recent years, there has been a growing interest in developing intervention programs that seek to minimize the impact of the changing nature of police work within a changing society and promote skills that enable police officers to deal more effectively with the current and future challenges. Therefore, the aim of this review is to systematize resilience training intervention programs and characterize their format, content, and efficacy. For that purpose, we searched four databases for resilience programs delivered to the police. We reached a final sample of 32 articles from a total of 550 published studies. The articles considered were divided into three main groups: mindfulness-based resilience interventions (n = 13), neurobiological-based resilience interventions (n = 13), and other resilience training interventions that did not fit in the previous categories (n = 6). There was much inter-intervention variability, mainly concerning their structure and approach. However, the intervention programs were relatively uniform in the topics covered, such as psychoeducation, police scenario simulation, and debriefing. Nonetheless, most studies found positive outcomes on the variables of interest, predominantly clinical and performance indicators (e.g., stress, anxiety, decision-making). Subsequent research endeavors could aim to determine the most reliable measure outcome measures for resilience variables and intervention efficacy, as alongside identifying pivotal occupational factors crucial to a robust and impactful resilience intervention.
PARP Inhibitors in Breast Cancer: a Short Communication
Authors: Daly Gordon R. , AlRawashdeh Maen Monketh , McGrath Jason , Dowling Gavin P. , Cox Luke , Naidoo Sindhuja , Vareslija Damir , Hill Arnold D. K , Young Leonie 
Published: January 2024

Abstract
Purpose of Review
In the last decade, poly (ADP-ribose) polymerase (PARP) inhibitors have been approved in the treatment of several cancers, such as breast and ovarian cancer. This article aims to discuss the current uses, limitations, and future directions for PARP inhibitors (PARPis) in the treatment of breast cancer.

Recent Findings
Following the results of the OlympiAD and EMBRACA trials, PARPis were approved in HER2-negative breast cancer with a germline BRCA mutation. We reviewed this class of drugs’ mechanism of action, efficacy, and limitations, as well as further studies that discussed resistance, impaired homologous recombination repair (HRR), and the combination of PARPis with other drugs.

Summary
Improving understanding of HRR, increasing the ability to target resistance, and combining PARPis with other novel agents are continuing to increase the clinical utility of PARPis.
Patentability of Brain Organoids derived from iPSC– A Legal Evaluation with Interdisciplinary Aspects
Authors: Wolff Hannes 
Published: January 2024

AbstractBrain Organoids in their current state of development are patentable. Future brain organoids may face some challenges in this regard, which I address in this contribution. Brain organoids unproblematically fulfil the general prerequisites of patentability set forth in Art. 3 (1) EU-Directive 98/44/EC (invention, novelty, inventive step and susceptibility of industrial application). Patentability is excluded if an invention makes use of human embryos or constitutes a stage of the human body in the individual phases of its formation and development. Both do not apply to brain organoids, unless ES-cells are used. Art. 6 (1) EU-Directive 98/44/EC excludes patentability for inventions “the commercial exploitation of which would be contrary to ordre public or morality”. While there is no conceivable scenario, in which the commercial application of current brain organoids violates the ordre public, the same is not necessarily true for future brain organoids. Keeping in mind that a development of consciousness-like abilities in future brain organoids cannot be excluded and that an ability for both physical and psychological suffering has been theorized, both of which are aspects of the ordre public, certain applications of future brain organoids may constitute a violation of the ordre public and therefore lead to an exclusion of patentability.
Aerodynamic interactions between distributed propellers and the wing of an electric commuter aircraft at cruise conditions
Authors: Schollenberger Michael , Kirsch Bastian , Lutz Thorsten , Krämer Ewald , Friedrichs Jens 
Published: January 2024

AbstractBeneficial interactions that occur between propellers and the wing can be used to increase the overall efficiency of an aircraft in cruise flight. Different concepts with such interacting propellers are distributed propulsion (DP) and wingtip mounted propellers (WTP). For DP, a full distribution over the entire span can be distinguished from a partial distribution, concentrating the propellers at the wing tip area. The paper focuses on the energy efficiency in cruise flight as a result of the interactions and provides a general comparison of the concepts (WTP, full and partial DP) with a Beechcraft 1900D commuter aircraft as a reference. Parametric CFD studies varying the number and the position of the propellers are performed with a half-wing model. The simulations are performed with the second-order finite-volume flow solver TAU, developed by the German Aerospace Center (DLR), employing Reynolds-averaged Navier–Stokes (RANS) equations. The propellers are modeled using an Actuator Disk (ACD). An algorithm is used to reach cruise condition by iteratively adjusting the propeller rotational speed and the wing angle of attack. The CFD results are analyzed and evaluated with respect to the overall efficiency including the aerodynamic efficiency of the wing as well as the propulsive efficiency of the propellers. The parameter study shows that in cruise flight partial DP is more efficient than a full DP. The pure WTP configuration was found as the optimum of the propeller distribution along the wing, resulting in a saving of required power of $$5.6\%$$

5.6
%

, relative to the reference configuration.
Effect of angular distortion and axial misalignment on the fatigue strength of welded and ground mild steel cruciform joints
Authors: Laher Benjamin , Buzzi Christian , Leitner Martin , Brunnhofer Peter 
Published: January 2024

AbstractThe focus of this work is to investigate the fatigue strength of a cruciform joint one-sided through-welded by a HV seam with a backing layer made of a 10-mm-thick S355 mild steel. The aim is firstly to analyse the effect of the deformation state incorporating angular distortion and axial misalignment on the fatigue strength of the tested specimens and secondly, the analysis of the benefit by grinding as post-treatment method on the resulting fatigue performance. The deformation impact is numerically investigated utilizing geometry measurements of the specimens as well as strain gauge measurements for validation. Thereby, the near notch stress under clamping condition without any load and under an additional static nominal load is analysed. Based on these investigations, the applied stress range for each tested specimen is converted to a “deformation-free” condition by means of the IIW-recommended km factor. The statistical analyses of the data points with and without this modification reveal a significant impact by the deformation state on both the evaluated fatigue strength and the scatter band. Moreover, this affects the evaluated benefit by grinding as post-treatment, whereas an increase of more than 40% in the fatigue strength at 2 million cycles is observed using the modified data points.
Autism Observation Scale for Infants: Systematic Review and Meta-Analysis in Samples at Increased Likelihood of Autism Spectrum Disorders
Authors: Reid Kyle , Sacrey Lori-Ann R. , Zwaigenbaum Lonnie , Brian Jessica A. , Smith Isabel M. 
Published: January 2024

AbstractThe Autism Observation Scale for Infants (AOSI) is being applied to non infant sibling populations. Assessment of the tool’s utility across increased likelihood (IL) populations is therefore needed. A systematic review and meta-analysis was conducted on 17 studies identified from six databases. The AOSI has been used in four IL contexts: infant siblings, infants with Fragile X Syndrome, Tuberous Sclerosis Complex, and Down Syndrome. There were three main findings: (1) five studies report classification data though no consistent approach was used; (2) group differences between IL-ASD, IL non-ASD, and controls started at 12-months; and (3) large effect sizes between IL-ASD and control samples was identified. Utility of the AOSI to identify early signs of ASD in IL populations was demonstrated.
CuCrZr Alloy Manufactured by LPBF Process: Correlation Between Microstructure, Mechanical and Thermal Properties
Authors: Biffi Carlo Alberto , Fiocchi Jacopo , Boldrini Stefano , Tuissi Ausonio 
Published: January 2024

AbstractCopper based alloys are promising materials for electrical and thermal devices. In this respect, the use of laser powder bed fusion (LPBF) allows the realization of 3D complex structures, possibly enhancing the functional performances of such devices. LPBF also induces refined microstructures and build-up of residual stresses, due to the rapid solidifications and high cooling rate. In this work a CuCrZr alloy was manufactured by LPBF and a process feasibility window was defined. The effect of a heat treatment, consisting of solution annealing and artificial aging, on the microstructure, tensile and thermal properties was evaluated. Moreover, particular attention was addressed to the effect of the building direction on the thermal behaviour.It was found that thermal conductivity is improved by the heat treatment and that thermal conductivity resulted anisotropic, being higher in the growth direction.
Boosting adversarial robustness via feature refinement, suppression, and alignment
Authors: Wu Yulun , Guo Yanming , Chen Dongmei , Yu Tianyuan , Xiao Huaxin , Guo Yuanhao , Bai Liang 
Published: January 2024

AbstractDeep neural networks are vulnerable to adversarial attacks, bringing high risk to numerous security-critical applications. Existing adversarial defense algorithms primarily concentrate on optimizing adversarial training strategies to improve the robustness of neural networks, but ignore that the misguided decisions are essentially made by the activation values. Besides, such conventional strategies normally result in a great decline in clean accuracy. To address the above issues, we propose a novel RSA algorithm to counteract adversarial perturbations while maintaining clean accuracy. Specifically, RSA comprises three distinct modules: feature refinement, activation suppression, and alignment modules. First, the feature refinement module refines malicious activation values in the feature space. Subsequently, the feature activation suppression module mitigates redundant activation values induced by adversarial perturbations across both channel and spatial dimensions. Finally, to avoid an excessive performance drop on clean samples, RSA incorporates a consistency constraint and a knowledge distillation constraint for feature alignment. Extensive experiments on five public datasets and three backbone networks demonstrate that our proposed algorithm achieves consistently superior performance in both adversarial robustness and clean accuracy over the state-of-the-art.