bluuebunny/crossref_metadata_2025_split huggingface dataset:
The m6A methylation and expression profiles of mouse neural stem cells after hypoxia/reoxygenation
Authors: Zhang Shaoqiong , Cui Kaile , Li Yuanyuan , Fan Yiting , Wang Dongxu , Yao Xingen , Fang Bo 
Published: February 2024

Abstract
Background
Ischemia–reperfusion injury to the central nervous system often causes severe complications. The activation of endogenous neural stem cells (NSCs) is considered a promising therapeutic strategy for nerve repair. However, the specific biological processes and molecular mechanisms of NSC activation remain unclear, and the role of N6-methyladenosine (m6A) methylation modification in this process has not been explored.

Methods
NSCs were subjected to hypoxia/reoxygenation (H/R) to simulate ischemia–reperfusion in vivo. m6A RNA methylation quantitative kit was used to measure the total RNA m6A methylation level. Quantitative real-time PCR was used to detect methyltransferase and demethylase mRNA expression levels. Methylated RNA immunoprecipitation sequencing (MeRIP-seq) and RNA sequencing (RNA-seq) were conducted for NSCs in control and H/R groups, and the sequencing results were analyzed using bioinformatics. Finally, the migration ability of NSCs was identified by wound healing assays, and the proliferative capacity of NSCs was assessed using the cell counting kit-8, EdU assays and cell spheroidization assays.

Results
Overall of m6A modification level and Mettl14 mRNA expression increased in NSCs after H/R treatment. The m6A methylation and expression profiles of mRNAs in NSCs after H/R are described for the first time. Through the joint analysis of MeRIP-seq and RNA-seq results, we verified the proliferation of NSCs after H/R, which was regulated by m6A methylation modification. Seven hub genes were identified to play key roles in the regulatory process. Knockdown of Mettl14 significantly inhibited the proliferation of NSCs. In addition, separate analysis of the MeRIP-seq results suggested that m6A methylation regulates cell migration and differentiation in ways other than affecting mRNA expression. Subsequent experiments confirmed the migration ability of NSCs was suppressed by knockdown of Mettl14.

Conclusion
The biological behaviors of NSCs after H/R are closely related to m6A methylation of mRNAs, and Mettl14 was confirmed to be involved in cell proliferation and migration.
Modeling SO2 dispersion from future eruptions in the Auckland Volcanic Field, New Zealand
Authors: Brody-Heine Siena , Katurji Marwan , Stewart Carol , Wilson Thomas , Smid Elaine R. , Trancoso Rosa 
Published: February 2024

AbstractAuckland city (pop. 1.7 M) is Aotearoa New Zealand’s largest city and an important economic hub. The city is built upon the active intraplate basaltic Auckland Volcanic Field (AVF). An AVF eruption would cause considerable impacts. An important component of volcanic risk management is assessing the likely volcanic hazards to help inform emergency planning and other preparedness activities. Previous volcanic hazard assessments for the AVF, particularly those for emergency planning scenarios, have modeled multiple volcanic hazards including lava flows, pyroclastic density currents, ballistic projectiles and tephra fall. Despite volcanic gas being an important and impactful hazard from intraplate basaltic field eruptions, there has been limited consideration of volcanic gas in AVF hazard assessment to date. This project is one of the first to quantitatively assess potential volcanic gas hazards for an explosive eruption scenario. For basaltic volcanism, sulfur dioxide (SO2) gas is typically the most consequential volcanic gas emitted. The aim of this exploratory study was to model SO2 dispersion from a high impact eruption during weather conditions conducive to high ground level pollutant concentrations. Since ground level SO2 concentrations are influenced by complex wind patterns resulting from interactions of locally driven flow circulations and topographically influenced weather, we modeled SO2 dispersion using the HYSPLIT model, a state-of-the art hybrid Eulerian and Lagrangian dispersion model widely used for volcanic gases, using high-resolution meteorological forcing fields given by the Weather Research and Forecasting (WRF) model.Modeled air parcel trajectories and ground level SO2 concentrations illustrate the effect of the converging sea breeze winds on SO2 dispersion. Under worst-case dispersion conditions, extensive areas of up to hundreds of square kilometers to the north and northwest of the eruption location would exceed New Zealand short-term (24 h) air quality standards and guidelines for SO2, indicating heightened health risks to downwind communities. Using this numerical modeling approach, this work presents a methodology for future applications to other AVF eruption scenarios, with a wider range of meteorological conditions that can help in exploring consequences for health services such as anticipated emergency department respiratory admissions.
The impact of the first and the second wave of the COVID-19 pandemic on vascular surgery practice in the leading regional center: a comparative, retrospective study
Authors: Stadnik-Zawalska Katarzyna , Tomys-Składowska Julia , Zawalski Patryk , Buczkowski Krzysztof , Migdalski Arkadiusz 
Published: February 2024

Abstract
Background
We conducted an analysis of the vascular surgery regional center reorganization in response to the first and the second wave of the coronavirus disease-2019 (COVID-19) pandemic to see what lessons we learned from the first wave.

Methods
The study included a total of 632 patients admitted to the vascular surgery department in three periods: March–May 2020, October–December 2020, and October–December 2019 as a control period.

Results
In the pandemic periods the number of admitted patients decreased in relation to the control period. There was a reduction in performed procedures. We observed an increase in the ratio of less invasive procedures. There was a significant decline in hospitalization time in comparison to the control period.

Conclusions
The reduction of scheduled admissions and procedures affected vascular centers all over the world. Minimally invasive procedures were more willingly performed to shorten the hospitalization time and reduce the patient's exposure to hospital infection. It allowed us to treat more patients during the second wave. Nevertheless, an increased number of vascular patients should be expected in the future, which will result from the failure to perform elective procedures during the pandemic.
Flexible emotional regulation typology: associations with PTSD symptomology and trait resilience
Authors: Spikol Eric , McGlinchey Emily , Robinson Martin , Armour Cherie 
Published: February 2024

Abstract
Background
Multiple factors influence posttraumatic stress disorder (PTSD) risk in trauma exposed individuals. An established association exists between trait resilience and decreased PTSD distress and between emotion regulation (ER) ability/flexibility and trait resilience. Typologies in ER ability/flexibility, associated with trait resilience and PTSD experience, could explain the difference in risk. This study aimed to explore the relationship between ER ability, ER flexibility, context sensitivity, resilience, and PTSD.

Methods
Data from N = 563 trauma exposed UK residents was used in a latent profile analysis (LPA) and membership in the resultant profiles was explored in a logistic regression of sociodemographics, resilience, and PTSD symptomology.

Results
Analysis showed 2 latent profiles (High Flexibility, Low Flexibility) typified by emotion regulation ability and context sensitivity. Members of the Low Flexibility profile were more likely to be younger, male, endorsing less trait resilience, and experiencing negative cognition/mood and hyperarousal PTSD symptomology.

Conclusions
Difficulties in ER ability and flexibility could be improved with targeted learning in a therapeutic or home setting, potentially increasing trait resilience after trauma exposure and reducing PTSD distress.
Facial emotion processing in patients with borderline personality disorder as compared with healthy controls: an fMRI and ECG study
Authors: Radimecká Monika , Látalová Adéla , Lamoš Martin , Jáni Martin , Bartys Patrik , Damborská Alena , Theiner Pavel , Linhartová Pavla 
Published: February 2024

Abstract
Background
Maladaptive behaviors and interpersonal difficulties in patients with borderline personality disorder (BPD) seem connected to biased facial emotion processing. This bias is often accompanied by heightened amygdala activity in patients with BPD as compared to healthy controls. However, functional magnetic resonance imaging (fMRI) studies exploring differences between patients and healthy controls in facial emotion processing have produced divergent results. The current study explored fMRI and heart rate variability (HRV) correlates of negative facial emotion processing in patients with BPD and healthy controls.

Methods
The study included 30 patients with BPD (29 females; age: M = 24.22, SD = 5.22) and 30 healthy controls (29 females; M = 24.66, SD = 5.28). All participants underwent the “faces” task, an emotional face perception task, in an fMRI session simultaneously with ECG. In this task, participants are presented with emotional expressions of disgust, sadness, and fear (as a negative condition) and with the same pictures in a scrambled version (as a neutral condition).

Results
We found no differences in brain activity between patients with BPD and healthy controls when processing negative facial expressions as compared to neutral condition. We observed activation in large-scale brain areas in both groups when presented with negative facial expressions as compared to neutral condition. Patients with BPD displayed lower HRV than healthy controls in both conditions. However, there were no significant associations between HRV and amygdala activity and BPD symptoms.

Conclusion
The results of this study indicate no abnormal brain activity during emotional facial processing in patients with BPD. This result contrasts with previous studies and more studies are needed to clarify the relationship between facial emotion processing and brain activity in patients with BPD. Possible reasons for the absence of brain activity differences are discussed in the study. Consistent with previous findings, patients showed lower HRV than healthy controls. However, HRV was not associated with amygdala activity and BPD symptoms.
Study on the correlation between real-time GNSS landslide acceleration monitoring and earthquake response: a case of May 2, 2023, MW = 5.2 Baoshan earthquake, Yunnan
Authors: Tao Zhigang , Li Mengnan , Sui Qiru , Mao Yuting , He Manchao , Jiang Yuebin 
Published: February 2024

Abstract
Background
Earthquakes and landslides pose significant threats to human safety and property, necessitating early warning systems. However, the high construction costs of earthquake early warning systems present a challenge.

Purpose
Landslide warnings are more prevalent, so linking them to earthquake warnings could address cost concerns. Hence, it is crucial to validate the feasibility of utilizing GNSS landslide monitoring as assistance for earthquake early warning systems.

Methods
This paper analyzes acceleration anomaly data from 31 GNSS landslide monitoring points near the epicenter of the May 2, 2023, MW = 5.2 Baoshan earthquake in Yunnan. The response time was determined as the time difference between an earthquake's occurrence and GNSS's acceleration anomalies. This calculation helps measure the time delay and sensitivity between these two events. Data were obtained from the geological disaster monitoring and early warning management system.

Results
GNSS landslide monitoring showed high sensitivity to nearby earthquakes. The fastest response time among the 31 data points was 8 seconds, while the slowest was 56 seconds, all falling within the one-minute mark. A linear correlation was found between acceleration anomaly response time and distance from the epicenter, indicating the feasibility of GNSS landslide monitoring-assisted earthquake monitoring.

Conclusion
A proposal is made for a GNSS landslide monitoring cluster to establish a multi-dimensional landslideearthquake disaster warning system. This approach offers new methods for combining earthquake and landslide early warning systems, leveraging existing infrastructure for cost-effectiveness and enhancing disaster preparedness.
A simplified model for measuring longevity risk for life insurance products
Authors: Atance David , Navarro Eliseo 
Published: February 2024

AbstractIn this paper, we propose a simple dynamic mortality model to fit and forecast mortality rates for measuring longevity and mortality risks. This proposal is based on a methodology for modelling interest rates, which assumes that changes in spot interest rates depend linearly on a small number of factors. These factors are identified as interest rates with a given maturity. Similarly, we assume that changes in mortality rates depend linearly on changes in a specific mortality rate, which we call the key mortality rate. One of the main advantages of this model is that it allows the development of an easy to implement methodology to measure longevity and mortality risks using simulation techniques. Particularly, we employ the model to calculate the Value-at-Risk and Conditional-Value-at-Risk of an insurance product testing the accuracy and robustness of our proposal using out-of-sample data from six different populations.
Field evaluation of whorl application of sand mixed or spray insecticides against Spodoptera frugiperda (Lepidoptera: Noctuidae) on yield of maize
Authors: Ismail Seham Mansour 
Published: February 2024

Abstract
Background
Spodoptera frugiperda (J.E. Smith) (Lepidoptera: Noctuidae), the fall armyworm (FAW), has recently invaded Egypt and poses serious threats to maize farmers as it causes huge economic costs and yield losses. Selection of efficient insecticides and appropriate methods of application can be a problem to control this pest.

Methods
Two-year field studies to effectiveness of whorl application (sand mixed or spray) of seven insecticides comprising new insecticides generations with conventional insecticides from different groups at maximum recommended dosage field rate against FAW on yield of maize was evaluated in maize fields at El-Qualubia Governorate, Egypt.

Results
In plots treated with insecticide mixed in sand, all tested insecticides recorded a significant decrease in FAW larvae with significantly higher yields than those treated with spraying or untreated plots. However, among tested insecticides in both applications, chlorantraniliprole was found to be the most effective followed by emamectin benzoate and spinosad and these insecticides gave better control FAW with higher yield than conventional insecticides tested. In this context, the highest decrease in FAW density was recorded in plots treated with chlorantraniliprole mixed in sand or sprayed (93.69% for 2021; 91.59% for 2022) and (84.74% for 2021; 85.78% for 2022), respectively, as well as a significantly high yield. However, lambda-cyhalothrin recorded the highest density of FAW (33.86% for 2021; 32.72% for 2022) in the treated plots with spraying with lowest significant yield during the 2021 and 2022 seasons in the treated plots with spraying by 8.98 and 8.00%, respectively, increase over control plots.

Conclusions
These results indicate that insecticides mixed in sand application are more efficacious against FAW larvae along with yield increase than spraying.
Bastard Sugar: Hortense Spillers and Paradoxes of Value in New World Thought
Authors: Parsard Kaneesha Cherelle 
Published: February 2024

AbstractIn the British Empire, bastard is a derogatory term for children born outside of the covenant of marriage, ineligible to inherit either status or property. This essay begins with a scene of research into this figure, and it then turns to investigate an unexpected, puzzling term: bastard sugar, the “impure” sugar left after many boilings. Its brief role in the age of emancipation, and the crisis that emancipation posed for West Indian sugar, raise questions about the relationship between racialization, value, and legitimacy in the New World. Guided by the thought of Hortense Spillers and her interlocutors, the essay concludes that “bastard sugar” showcases the paradoxes of value in financial markets, and as such is the condition of New World thought.
Beyond conventional therapies: exploring the role of Pilates in neurological physical therapy – a review of the latest research
Authors: Maleszewska Monika , Żmijewska Aleksandra , Nowak Gabriela , Sztybór Mateusz , Piątkiewicz Julia , Krzyżanowska Maria , Wojtas Mikołaj , Momot Karol , Głogowska Karen , Kapica Marcin 
Published: February 2024

Pilates exercise method, characterized by its holistic approach, underscores core stability, strength, and flexibility, coupled with meticulous muscle control, optimal posture, and focused attention on breathing. Widely embraced in both general and clinical fitness realms, this study aims to evaluate the integration of Pilates into physical therapy practices for patients with neurological disorders.
Existing studies indicate the potential efficacy of Pilates in diverse rehabilitation contexts. However, neurological disorders, specifically multiple sclerosis (MS) and Parkinson's disease (PD), have been the primary focus. While systematic reviews and meta-analyses suggest Pilates as a plausible option in physiotherapy for PD and MS patients, a paucity of research on this subject necessitates a comprehensive review of recent original studies.
Analysis of gathered data suggests that Pilates, when incorporated, may yield benefits for patients with various neurological disorders. Consideration of Pilates as a supplementary element to physical activity for those with PD and MS emerges as a reasonable proposition. The study also encourages contemplation of Pilates in rehabilitation research across a broader spectrum of neurological disorders. Subsequent investigations, incorporating relevant considerations, will contribute to a nuanced understanding of Pilates' potential benefits and its comparative advantages over traditional interventions for neurological disorders.
Decoding the Images of the Polish Countryside, by Louise Arner Boyd (1887-1972)
Authors: Buriak Larysa , Kudela-Świątek Wiktoria 
Published: February 2024

This article looks at the photographic legacy of Louise Arner Boyd’s (1887-1972) expedition through the Second Polish Republic in the context of her discovery of the otherness and social diversity of the country she visited in 1934. The authors were particularly captivated by the portrayal of the Ruthenians/Ukrainians of what is now Western Ukraine, as depicted in the Boyd photography. The authors focus lies on the unprocessed photographic content from the library collections of the University of Wisconsin-Milwaukee and the book she published a few years after her journey with the cooperation of the American Geographical Society in New York. The authors told the story of Louise A. Boyd’s trip to Poland primarily to introduce the reader to the context of the creation of the photographic collection, in which authors try to discover content and meanings that have not been sought before. Their analysis of the making-off process and reception into academia for Boyd’s book entitled Polish Countryside is also crucial to understanding that it is only a part of the collection. It is a specific vision and a compromise between the photographer’s and the publisher’s expectations. The Boyd photographic collection focused on rural landscapes and the architecture of villages and farms, capturing various farming methods, road and water transport scenes, village types and traditional clothing. With meticulous descriptions and detailed lists of the photographed locations and subjects, the collection serves as valuable documentation of building styles and techniques, traditional costumes, transportation, markets and agricultural and fishing practices. Thanks to Boyd’s skilled photographer’s eye, she was able to capture visually attractive photographs that also serve as scientifically intriguing documents of a bygone era. The significance of these photos extends beyond the confines of ethnography, as we have endeavoured to emphasise in this article. Through reinterpreting Ruthenians/ Ukrainians portraits in Boyd photographs after almost a century, we aim to grasp the preserved and concealed contexts, thereby reconstructing, if not the complete image, at least its distinct components. However, the images of contemporary Western Ukraine and its inhabitants by Louise Arner Boyd that the authors analysed are currently in the photography collection mentioned above from the UWM as part of the digitalised archive of the American Geographical Society. The authors had attempted to look at them both as an example of ethnographic photography typical of the interwar period and a unique image of a world that no longer exists. In the authors’ opinion, Louise A. Boyd’s photograms, placed as raw ethnographic material in the mentioned repository of the UWM library, today have the value that she wanted to give them from the beginning when she was considering the publication of Polish Countrysides, and they are a reminder of a world whose traces have almost disappeared today.