bluuebunny/crossref_metadata_2025_split huggingface dataset:
Diabetes screening outcomes in youth presenting for paediatric weight management: A report of the Paediatric Obesity Weight Evaluation Registry
Authors: Kumar Seema , King Eileen , Binns Helen J. , Christison Amy , Cuda Suzanne E. , Yee Jennifer K. , Joseph Madeline , Kirk Shelley 
Published: February 2024

SummaryObjectiveRising prevalence of obesity has led to increased rates of prediabetes and diabetes mellitus (DM) in children. This study compares rates of prediabetes and diabetes using two recommended screening tests (fasting plasma glucose [FPG] and haemoglobin A1c [HbA1c]).Study DesignData were collected prospectively from 37 multi‐component paediatric weight management programs in POWER (Paediatric Obesity Weight Evaluation Registry).ResultsFor this study, 3962 children with obesity without a known diagnosis of DM at presentation and for whom concurrent measurement of FPG and HbA1c were available were evaluated (median age 12.0 years [interquartile range, IQR 9.8, 14.6]; 48% males; median body mass index 95th percentile [%BMIp95] 134% [IQR 120, 151]). Notably, 10.7% had prediabetes based on FPG criteria (100–125 mg/dL), 18.6% had prediabetes based on HbA1c criteria (5.7%–6.4%), 0.9% had DM by FPG abnormality (≥126 mg/dL) and 1.1% had DM by HbA1c abnormality (≥6.5%). Discordance between the tests was observed for youth in both age groups (10–18 years [n = 2915] and age 2–9 years [n = 1047]).ConclusionThere is discordance between FPG and HbA1c for the diagnosis of prediabetes and DM in youth with obesity. Further studies are needed to understand the predictive capability of these tests for development of DM (in those diagnosed with prediabetes) and cardiometabolic risk.
“The third wing of the plane”: Fathers' perceptions of their role in the treatment process for daughters with eating disorders
Authors: O'Sullivan Hazel , Goodwin John , O'Malley Maria , Happell Brenda , O'Donovan Aine 
Published: February 2024

AbstractEating disorders are complex mental health conditions exacerbated by high mortality rates. International and national guidelines recommend family involvement in the treatment process, recognising the family as an important source of support to young people. Research suggests fathers engage less in the process compared to mothers. In studies exploring parental perspectives, most samples consisted of mothers, with fathers minimally represented. Few studies explore family involvement from the perspective of fathers. This study aimed to explore the experiences of fathers regarding their involvement in the treatment process. Qualitative descriptive methods were used, involving focus group interviews of seven fathers. Interviews were assisted by a semi‐structured interview guide. A qualitative content analysis approach was used to analyse the data regarding paternal experiences of engagement in the treatment process. Fathers understood the importance of the whole family working together but viewed mothers as taking a more central role in the treatment process, with fathers more at the periphery. Gender emerged as an influencing factor in paternal involvement, with mothers primarily taking on responsibility for the child with the eating disorder and fathers providing secondary support. Healthcare providers need to be aware of the contribution of gendered roles within the family system and consider this when working with families within the treatment process. Consequently, mental health nurses have an important role in encouraging fathers to become actively involved in the treatment process.
Effect of transconjunctival sutureless vitrectomy versus 20‐G vitrectomy on surgical wound closure in patients: A meta‐analysis
Authors: Huang Yan , Sun Jun , Wang Jimin , Zhang Xuedong , Chen Zhongpei 
Published: February 2024

AbstractA meta‐analysis was conducted to evaluate the impact of transconjunctival sutureless vitrectomy (TSV) over 20 G vitrectomy on wound healing, as well as the requirements for closing the wound in order to treat vitreoretinal diseases. Among the 500 cases who had been treated with vitrectomy to September 2023, 250 were treated by transconjunctiva without vitrectomy and 250 were treated with 20 G vitrectomy. The odds ratio (OR) and mean difference (MD) of 95% confidence interval (CI) were computed to evaluate the influence of wound opening and closing on vitrectomy diseases. The evaluation of vitreoretinal diseases was performed with either a random‐or fixed‐effect model, which involved TSV compared to 20 G vitrectomy. Compared to 20 G vitrectomy, the opening time of the wound in TSV was less (MD, −2.03; 95% CI, −2.87, −1.19; p < 0.0001); Compared to 20 G vitrectomy, the closing time of the wound was less (MD, −4.84; 95% CI, −6.38, −3.03; p < 0.0001); Nevertheless, there were no statistically significant differences in the incidence of vitreous haemorrhage after TSV surgery compared with 20 G vitrectomy (OR, 0.74; 95% CI, 0.25, 2.18; p = 0.59). TSV vitrectomy can shorten the duration of the operation and speed up the healing of the wound. It is suggested that additional studies be carried out with a larger sample size in order to verify this conclusion.
Knowledge mapping and research trends of stem cell in wound healing: A bibliometric analysis
Authors: Sun Nianzhe , Sun Yu , Xing Yixuan , Xu Laiyu , Chen Zijie , Qing Liming , Wu Panfeng , Tang Juyu 
Published: February 2024

AbstractWound nonhealing is a common and difficult problem in clinic. Stem cells are pluripotent cells, and their undifferentiated and self‐replicating characteristics have attracted much attention in the regenerative medicine‐related researches. New treatment approaches might result from an understanding of the function of stem cells in wound healing. Using bibliometric techniques, this study proposed to analyse the research status, hotspots, and research trends in stem cell and wound healing. By using the Web of Science Core Collection (WoSCC), we conducted an in‐depth review of publications on stem cells in wound healing from 1999 to 2023. We used scientometric analysis methods to examine annual trends, institutions, countries, journals, authors, keywords, co‐occurrence references and their closed relationship, revealing present hotspots and potential future advancements in this field. We analysed 19 728 English studies and discovered a consistent rise in annual publications. The United States and China were the two countries with the most publications. The most three influential institutions in the field were Shanghai Jiao Tong University, Sun Yat‐sen University, and University of Pittsburgh. International Journal of Molecular Sciences and Biomaterials were considered the most influential journals in this field. International Journal of Molecular Sciences had the most publications, and the most quantity of citations and the highest H‐index were found in Biomaterials. The dual‐map overlay revealed that publications in Molecular/Biology/Genetics and Health/Nursing/Medicine co‐cited journals received the majority of the citations for studies from Molecular/Biology/Immunology and Medicine/Medical/Clinical. In terms of publication production and influence, Fu X stood out among the authors, and Pittenger MF took the top spot in co‐citations. According to the keywords from the analysis, future research should concentrate on the mechanisms through which stem cells promote wound healing. We conducted a thorough analysis of the general information, knowledge base and research hotspots in the field of stem cells and wound healing from 1999 to 2023 by using the VOSviewer, CiteSpace, and other bibliometric analysis tools. It not only provided valuable insights for scholars, but also served as a reliable reference that drives further development in the field and stimulates the interest of researchers.
Comparing the Waterlow and Jackson/Cubbin pressure injury risk scales in intensive care units: A multi‐centre study
Authors: Yang Qiuxia , Yang Zhuang , Lv Lin , Zhang Hongyan , Tao Hongxia , Pei Juhong , Ma Yuxia , Han Lin 
Published: February 2024

AbstractTo compare the predictive properties of the Jackson/Cubbin scale and Waterlow scales in intensive care unit patients. A multi‐centre study. This study was conducted between April 2021 and February 2023 in 72 intensive care units of 38 tertiary hospitals in Gansu Province, China. All adults admitted to the intensive care unit for 24 hours or more without pressure injury on admission were screened using the Waterlow scale and Jackson/Cubbin scales in intensive care. Additionally, the negative predictive value, positive predictive value, sensitivity, specificity and receiver operating characteristic curve with area under the curve of the Waterlow scale and Cubbin/Jackson scales were determined. The participant population for this study included 6203 patients. Predictive properties for the Jackson/Cubbin scales and Waterlow scales, respectively, were as follows: Cut‐off scores, 28 versus 22; AUC, 0.859 versus 0.64; sensitivity, 92.4% versus 51.9%; specificity, 67.26% versus 71.46%; positive predictive value, 35% versus 23%; negative predictive value, 99.9% versus 99.1%. Both Waterlow scales and Jackson/Cubbin scales could predict pressure injury risk for patients in the intensive care unit. However, the Jackson/Cubbin scale demonstrated superior predictive properties than the Waterlow scale.
Enhancing wound recovery in chemotherapy‐induced leukopenia for malignant tumours: A meta‐analysis of acupuncture treatment efficacy
Authors: Wang Haoyang , Pan Junying , Tan Zengde , Zhang Mingming 
Published: February 2024

AbstractThis meta‐analysis study aimed to assess the effectiveness of acupuncture in enhancing wound recovery in patients experiencing leukopenia following chemotherapy for malignant tumours. A comprehensive search was conducted to collect randomized controlled trials and observational studies focusing on leukopenia post‐chemotherapy in malignant tumour patients. Data analysis was performed using Revman 5.3 software. Eleven articles were included, encompassing 957 patients. The meta‐analysis revealed that, compared with control groups, patients receiving acupuncture showed a significantly higher total effectiveness rate (p < 0.05). Subgroup analysis indicated superior outcomes in groups receiving acupuncture combined with moxibustion (p < 0.05) and acupuncture combined with Western medicine (p < 0.05), with the former outperforming the latter. Notably, acupuncture was found to improve white blood cell (WBC) counts on 3rd, 7th, 14th, 21st and 28th days post‐treatment, with significant differences compared with control groups. These improvements were time dependent and more pronounced than in control groups. Acupuncture demonstrated significant, time‐dependent capability to enhance wound recovery in leukopenia following chemotherapy for malignant tumours. The combination of acupuncture and moxibustion was found to be more effective than acupuncture combined with Western medicine. This study highlighted the potential of acupuncture as a complementary therapy in managing chemotherapy‐induced leukopenia, contributing positively to the wound healing process in cancer patients.
Effects of exercise in treating patients with venous leg ulcers: An umbrella review
Authors: Shen Min , Xing Mengzhen , Jiang Hehe , Zhang Linlin , Chen Chen , Ma Yuning , Ma Yuxia 
Published: February 2024

AbstractVenous leg ulcers (VLUs) represent a substantial challenge within the healthcare landscape, thereby necessitating efficacious therapeutic strategies. Exercise has been investigated as a prospective intervention to bolster the management of VLUs. The objective of this comprehensive review is to systematically scrutinize and appraise the extant body of evidence pertaining to the impact of exercise on the treatment of patients diagnosed with VLUs. A comprehensive literature search was executed across multiple databases, encompassing PubMed, the Cochrane Library, Web of Science, Embase, and Google Scholar. The methodological rigour was evaluated utilizing the Assessment of Multiple Systematic Reviews 2 (AMSTAR‐2) instrument, while the quality of the evidence was appraised via the Grading of Recommendations Assessment, Development and Evaluation (GRADE) classification system. The relative efficacy of exercise interventions on outcomes related to VLUs, including rates of wound healing, total range of motion in the ankle joint, and adherence rates, was synthesized. Data were consolidated employing fixed‐effects models, and the impact of exercise on these outcomes was visually represented through the use of forest plots. The methodological foundation of this investigation comprised four systematic reviews and meta‐analyses, each characterized by an intermediate level of methodological rigour and evidence quality. Subsequent analyses revealed that exercise interventions exert a multifaceted and favourable impact on the therapeutic landscape of VLUs. These interventions distinctly contribute to the enhancement of wound healing rates (risk difference 0.17, 95% confidence interval [CI]: 0.06–0.28) and the extension of ankle range of motion (mean difference [MD] 6.10, 95% CI: 4.61–7.59). Furthermore, Pooled adherence rate was 0.70 (95% CI: 0.20–2.45) with no significant heterogeneity. In conclusion, although existing evidence supports the positive impact of exercise training on VLUs, higher‐quality research is still needed to deepen our understanding of its effects and provide more specific guidance for clinical practice.
RETRACTED: Effects of comprehensive nursing intervention in patients with diabetic foot ulcers: A meta‐analysis
Authors: Feng Yong‐Li , Yu Li 
Published: February 2024

AbstractThis study systematically evaluates the impact of comprehensive nursing interventions on the treatment efficacy for patients with diabetic foot ulcers. Utilizing computerized searches of databases including PubMed, Embase, Google Scholar, Cochrane Library, China National Knowledge Infrastructure and Wanfang databases, we identified randomized controlled trials pertaining to this topic, with the search timeframe extending to May 2023. Two independent researchers screened the literature, extracted data and conducted a quality assessment. Data analysis was performed using Stata 17.0 software. A total of 17 randomized controlled trials, encompassing 1306 patients with diabetic foot ulcers, were included in this analysis. The analysis revealed that the application of comprehensive nursing interventions significantly reduced the wound healing time in patients with diabetic foot ulcers (standard mean difference [SMD] = −2.44, 95% confidence interval [CI]: −3.05 to −1.83, P < 0.001). Additionally, there was a notable enhancement in nursing satisfaction (odds ratio [OR] = 7.54, 95% CI: 3.99–14.26, P < 0.001) and the overall treatment efficacy rate (OR = 6.97, 95% CI: 3.32–14.60, P < 0.001). This study demonstrates that comprehensive nursing interventions significantly shorten the wound healing time in patients with diabetic foot ulcers, enhance clinical nursing satisfaction and improve the overall efficacy of treatment. These findings underscore the value of such interventions for widespread clinical application.
Bandgap engineering—Influence of the evolution of (Zn/Mg)Al2O4:Cr3+ spinel phosphors on the photoluminescence properties
Authors: Qiang Ming , Yin Xiaomeng , Tang Yang , Xu Xueke , Lin Hui , Zhang Dawei 
Published: February 2024

AbstractAs a luminescent center ion in materials for deep red and near‐infrared light, Cr3+ has been extensively studied in octahedral host materials. In this study, using zinc aluminate (ZnAl2O4) and magnesium aluminate (MgAl2O4) spinels with abundant octahedra as substrates, a series of Zn1−xMgxAl2O4:0.5%Cr3+ (x = 0, 0.2, 0.4, 0.6, 0.8, and 1) fluorescent powders were first prepared via a high‐temperature solid‐state method. The influence of different Mg/Zn ratios on (Zn/Mg)Al2O4:0.5%Cr3+ optical properties was thoroughly explored. Experimental results show that an increase in the Mg/Zn ratio reduces the crystal field strength (Dq) and leads to distortion of the [AlO6] octahedra, resulting in broadening of the photoluminescence emission spectrum. Furthermore, the addition of Mg gradually reduces the formation of inverse spinel. An appropriate Mg/Zn ratio can improve luminescent intensity and quantum efficiency. In summary, this paper, through bandgap engineering by adjusting the Mg/Zn ratio, provides a detailed account of the changes in optical properties and the underlying mechanisms during the transition from ZnAl2O4:0.5%Cr3+ to MgAl2O4:0.5%Cr3+ spinels. It offers valuable insights for further research on the practical applications of Cr3+ in areas such as lighting displays and bioimaging.
Phytochemical analysis and antibacterial activity of palm waste extract against Vibrio harveyi and Vibrio parahaemolyticus
Authors: Nasmia Nasmia , Serdiati Novalina , Tahya Akbar Marzuki , Safir Muhammad 
Published: February 2024

AbstractVibrio harveyi and Vibrio parahaemolyticus are species of the Vibrio genus that often cause disease and mass mortality in crustaceans. If not handled quickly and appropriately, these diseases can cause considerable losses to farmers. Therefore, it is necessary to find a solution with safe and environmentally friendly disease prevention technology using natural ingredients, among others from plants, namely oil palm. Some parts of oil palm, namely leaves, fronds, fibres and oil palm pulp, which are palm waste, contain antibacterial compounds. This study aimed to assess the antibacterial activity of palm waste extracts, namely pulp, leaves, fronds and fibres using n‐hexane, ethyl acetate, chloroform, ethanol and water maceration solvents against pathogenic bacteria V. harveyi and V. parahaemolyticus, and identify active compounds contained in palm waste. The results of the research are expected to produce innovative and sustainable solutions to control diseases in shrimp farming, contribute to the development of a sustainable fishing industry and open up the potential for utilizing palm waste as a value‐added resource in the field of aquatic health. The results of observations on antibacterial activity tests and identifying the content of palm waste extract compounds were analysed descriptively displayed in the form of figures, tables and graphs. The results showed that palm waste extracts (pulp, leaves, fronds and fibres) with ethyl acetate and ethanol maceration solvents had very strong antibacterial potential, namely 20.14 ± 0.31 mm–25.52 ± 1.42 mm on V. harveyi bacteria and 20.41 ± 0.55 mm–25.00 ± 0.51 mm on V. parahaemolyticus bacteria. Palm extracts with n‐hexane (>20 mm) and chloroform solvents generally have strong category antibacterial potential (10–20 mm), and palm extracts in water solvents have medium category potential (5–10 mm) against V. harveyi and V. parahemolyticus bacteria. The results of phytochemical tests on palm waste extracts with ethyl acetate and ethanol maceration solvents contain bioactive compounds of flavonoids, saponins, polyphenols and alkaloid tannins, steroids and triterpenoids. Palm extracts with n‐hexane and chloroform solvents generally contain saponins, alkaloids, steroids and triterpenoids, while palm waste extracts with water solvents contain saponins.
Efficacy of ceramides and niacinamide‐containing moisturizer versus hydrophilic cream in combination with topical anti‐acne treatment in mild to moderate acne vulgaris: A split face, double‐blinded, randomized controlled trial
Authors: Tempark Therdpong , Shem Andrew , Lueangarun Suparuj 
Published: February 2024

AbstractIntroductionTopical therapy is the mainstay treatment of acne, and topical retinoids such as tretinoin, tazarotene, and adapalene are recommended as the first‐line therapy for mild to moderate acne. However, the cutaneous irritations may occur, and the dermocosmetics are recommended to prevent side effects of anti‐acne drugs and adhere to treatment. Thus, this study aims to compare the efficacy and tolerability of ceramides and niacinamide‐containing moisturizer (CCM) versus hydrophilic cream in combination with topical anti‐acne treatment in mild to moderate acne vulgaris.MethodsThis was an 8‐week, randomized, double‐blinded, split face study in 40 patients assigned for topical anti‐acne medications (5% benzoyl peroxide and 0.1% adapalene gel), then randomly applied CCM or hydrophilic cream. All patients were followed at week 0, 2, 4, and 8 for acne improvement, adverse reactions, biometric, and biophysical evaluation.ResultsCCM could significantly improve the non‐inflammatory, inflammatory, and total acne lesions compared with hydrophilic cream after week 8 of treatment. Interestingly, there was an improvement of global worst score, hemoglobin index, melanin index, TEWL, skin hydration, sebum production, and skin surface pH, with no statistically significant differences between the two treatments. No serious side effects from clinical application of CCM and hydrophilic cream in mild to moderate acne vulgaris patients.ConclusionCeramide and niacinamide‐containing moisturizer in combination with anti‐acne medication can significantly improve acne lesions and decrease cutaneous irritations toward a satisfactory treatment outcome of mild to moderate acne vulgaris.
Partially replacing plant protein sources with torula yeast in rainbow trout (Oncorhynchus mykiss) feed increases growth and factors related to immune status
Authors: Ekmay Ricardo D. , Plagnes‐Juan Elisabeth , Aguirre Pierre , Surget Anne , Terrier Frédéric , Frohn Laura , Skiba‐Cassy Sandrine 
Published: February 2024

AbstractIn this study, the impact of adding 10% or 20% torula yeast (PB TY10 and PB TY20) to a fishmeal‐free diet on digestibility and growth of juvenile rainbow trout was assessed. The yeast diets were compared with a plant‐only diet (PB) and a diet containing 20% fishmeal (FM). The apparent digestibility of dry matter, protein, energy, and ash of yeast in trout (~120 g) were 78.6%, 93.8%, 84.8%, and 48.7%, respectively. All PB diets had higher protein digestibility and PB TY20 had higher ash digestibility than the FM diet. To assess growth, trout (~44 g) were divided into triplicate tanks (30 per tank) and fed one of the four experimental diets for 12 weeks. The PB diet resulted in lower growth and daily feed intake (p < 0.05), but adding yeast significantly improved them. Final weight of PB TY10 did not differ significantly from that of FM. Expression of oclna and cldn15 in the proximal intestine increased in trout fed yeast (p < 0.05). Expression of tlr2, mcsfr, and tnfa, as well as the plasma lysozyme concentration, increased with PB TY20 (p < 0.05). In conclusion, torula yeast has the potential to improve the robustness and growth of rainbow trout in the context of fishmeal‐free diets.