bluuebunny/crossref_metadata_2025_split huggingface dataset:
ASSOCIATIONS OF LOW-DENSITY LIPOPROTEIN CHOLESTEROL LEVEL WITH BIOMOLECULES IN METABOLIC DISORDERS IN YOUNG PEOPLE AGED 25–44 YEARS
Authors: Kashtanova Elena V. , Polonskaya Yana V. , Shcherbakova Lilia V. , Stakhneva Ekaterina M. , Shramko Victoria S. , Spiridonov Alexander N. , Ragino Yulia I. 
Published: October 2023

Highlights The study is devoted to the analysis of metabolic hormones and their relationship with the main risk factors for cardiovascular diseases, in particular, elevated levels of low-density lipoprotein cholesterol. The study included people under the age of 45 with active hormones. AbstractAim. To assess the relationship between the levels of LDL and metabolic hormones reflecting metabolic disorders in young people.Methods. The study included 305 people. The group 1 included 146 people with an LDL level of <2.1 mmol/L, the group 2 included 159 people with an LDL level of ≥4.2 mmol/L. Serum total cholesterol (TC), triglycerides, HDL and glucose concentrations were determined by enzymatic method using Thermo Fisher Scientific kits (Finland) on a 30i KonelabPrime clinical chemistry analyzer. The calculation of concentrations of LDL was carried out according to the Friedwald formula. The levels of amylin, C-peptide, ghrelin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1 (GLP-1), glucagon, interleukin 6, insulin, leptin, monocyte chemoattractant protein-1, pancreatic polypeptide, peptide YY, tumor necrosis factor alpha were determined by multiplex analysis using the Human Metabolic Hormone V3 (MILLIPLEX) panel on a Luminex MAGPIX flow fluorimeter.Results. In the group of patients with LDL ≥4.2 mmol/L, fasting glucose disorders were much more prevalent, the average BMI (p = 0,0001) was higher, and arterial hypertension was twice as frequent (24.8% vs. 11.6%, p = 0.003) compared with the group 1. The levels of triglycerides, TC, and glucose were higher, whereas HDL level was lower in the group 2(p = 0,0001). In patients with LDL ≥4.2 mmol/L, the values of HOMA-IR and the occurrence of IR (83.8%) according to the HOMA-IR were higher compared with the group with LDL <2.1 mmol/L (p = 0,0001). Statistically significant differences in the levels of the studied indicators between the groups 1 and 2 were obtained for C-peptide, GLP-1, insulin and leptin. The relative chance of having LDL≥4.2 mmol/L is associated with an increase in the level of C-peptide (OR = 2.042, 95% CI 1.209–3.449, p = 0.008) and a decrease in the level of GLP-1 (OR = 0.997, 95% CI 0.996–0.999, p = 0.001).Conclusion. An increase in LDL levels in young people is associated with disorders of lipid and carbohydrate metabolism. These data are confirmed by changes in the serum metabolic markers that characterize metabolic disorders in the human body.
CURRENT VIEWS ON THE ROLE OF GROWTH DIFFERENTIATION FACTOR 15 IN THE GENESIS, COURSE AND OUTCOME OF CARDIOVASCULAR PATHOLOGY
Authors: Ibragimova Regina E. , Zakharyan Elena A. 
Published: October 2023

HighlightsThe article summarizes the data on the influence of growth and differentiation factor 15 on the genesis, course and outcomes of cardiovascular system pathologies. The presented analysis of experts' opinions allows to approach the answer to the question, which is topical in the scientific community: whether this factor promotes the progression of cardiovascular diseases or performs a protective function. AbstractGrowth and differentiation factor 15 (GDF-15) is a circulating protein and is associated with a variety of pathological processes, including being a marker of endothelial dysfunction. GDF-15 expression is upregulated in cardiomyocytes after ischemia, reperfusion, pressure overload and mechanical stretch, allowing it to be used for the diagnosis of subclinical coronary atherosclerosis, arterial hypertension and heart failure. This paper presents a review of studies that have focused on the diagnostic spectrum of this marker. We also considered two perspectives on the role of GDF-15 in the pathogenesis of cardiovascular disease: as a factor contributing to pathology progression or as performing a compensatory function? The introduction of highly specific markers, in particular GDF-15, into clinical practice may help to reduce the risk of cardiovascular complications, disability and mortality.
Stress State and Earthquake Triggering on the Outer Rise of the Southern Vanuatu Subduction Zone, Southern New Caledonia
Authors: Chin Shao-Jinn , Sutherland Rupert , Savage Martha K. , Collot Julien , Monge Olivier , Townend John 
Published: October 2023

ABSTRACT
An analysis of earthquakes recorded in southern New Caledonia (SNC) over 14 months during 2018–2019 reveals focal mechanisms consistent with a normal-faulting stress state. The minimum principal stress is perpendicular to the Vanuatu subduction zone (VSZ), which is 200 km away, and is highly oblique to the local topographic ridge of New Caledonia, which may induce additional tension. An Mw 7.5 earthquake occurred in VSZ on 5 December 2018, and focal mechanisms appear to be different to those before the big earthquake. Significant increase in seismicity rates in both VSZ and SNC are observed following this large earthquake. A strong correlation between local and subduction zone seismicity rates is confirmed by analyses of seismic records before and after large subduction zone earthquakes 200–350 km away during the period of 2000–2018. The local seismicity rate and seismic hazard in SNC is about four times higher immediately after a large subduction earthquake, and Omori decay returns it to background levels after about 30 days. The triggering mechanisms remains unclear, but our study provides the first observations and a framework for future work.
Back-Azimuth Estimation of Air-to-Ground Coupled Infrasound from Transverse Coherence Minimization
Authors: Bishop Jordan W. , Haney Matthew M. , Fee David , Matoza Robin S. , McKee Kathleen F. , Lyons John J. 
Published: October 2023

AbstractWe present the transverse coherence minimization method (TCM)—an approach to estimate the back-azimuth of infrasound signals that are recorded on an infrasound microphone and a colocated three-component seismometer. Accurate back-azimuth information is important for a variety of monitoring efforts, but it is currently only available for infrasound arrays and for seismoacoustic sensor pairs separated by 10 s of meters. Our TCM method allows for the analysis of colocated sensor pairs, sensors located within a few meters of each other, which may extend the capabilities of existing seismoacoustic networks and supplement operating infrasound arrays. This approach minimizes the coherence of the transverse component of seismic displacement with the infrasound wave to estimate the infrasound back-azimuth. After developing an analytical model, we investigate seismoacoustic signals from the August 2012 Humming Roadrunner experiment and the 26 May 2021 eruption of Great Sitkin Volcano, Alaska, U.S.A., at the ranges of 6.5–185 km from the source. We discuss back-azimuth estimates and potential sources of deviation (1°–15°), such as local terrain effects or deviation from common analytical models. This practical method complements existing seismoacoustic tools and may be suitable for routine application to signals of interest.
Los archivos represivos en los procesos de "justicia transicional": una cuestión de derechos
Authors: Caetano Gerardo 
Published: October 2023

A partir de una concepción renovada de los procesos de "justicia transicional", este artículo presenta una reflexión a propósito de un tópico con frecuencia olvidado pero relevante en lo que comúnmente se denomina políticas de memoria: el tratamiento de los archivos represivos como una cuestión de derechos humanos. El texto, en primer lugar, remite a ciertas características generales del tema, tomando como referencia ilustrativa la situación uruguaya en la materia; para después abordar el punto desde una visión más global, registrándose las principales pautas orientadoras que indica la experiencia internacional más reciente en la materia.AbstractThe concept of "transitional justice" and its related processes have experienced a renovation. This article presents some thoughts about a frequently forgotten subject which has special importance in the field of the so called "memory policies": the treatment of the repression files as a matter of human rights. In the first place, the text deals with some features of the Uruguayan situation as a reference point. Then, the topic is considered from a global point of view which shows the main guidelines of the most recent international experience on the subject.
A Journey through the Potential of Research to Drive Innovation in University Education
Authors: Aranibar Ramos Edgar Romario , Ramos Castillo Roberto Guillermo , Zanabria Cabrera Luis Carlo 
Published: October 2023

This essay aims to explore effective ways to utilize research in improving the quality of university education and address challenges that impede its potential. The authors conducted a multivocal literature review and approached six subtopics, including the role of interdisciplinary research and collaboration, the impact of research on teaching practices and student outcomes, the potential of emerging technologies, the importance of diversity, equity, and inclusion, fostering a culture of research and innovation, and the role of funding and resources. They recommend investment in research infrastructure, the promotion of collaboration, engagement, and ethical principles, and building a culture of research. Implementing these recommendations will enable universities to utilize research effectively in order to enhance the quality of university education, drive progress, and contribute to more inclusive, equitable, and sustainable societies.
V.V. Vereshchagin and the "invention" of the North in literature and journalism of the late XIX – early XX century (part one)
Authors: Vsevolodov A. 
Published: October 2023

In the Russian intellectual space of the last quarter of the XIX – early XX centuries the North of the European part of the country was increasingly recognized as a special historical and cultural area. Remaining as before in the position of colonized outskirts with a huge but still unclaimed economic potential, now the North has begun to arouse interest of a different kind. In the reign of Alexander III, its political and strategic importance was realized; moreover, with the advent of the first railways in the region, it became much more accessible for travel than before. As a result, in the 1890s a specific northern discourse was being formed in journalism. A key role in this process was played by the travel notes of the Arkhangelsk governor A.P. Engelhardt (1897), in which the nomination "Russian" was used for the first time in relation to the North, although not in an ethnic, but in a political sense. In constructing the image of the region, ideas about its "abandonment", isolation were also used. The North was portrayed as a territory that passed the peak of its development in the XVI–XVII centuries, and then became more and more isolated from the rest of Russia, primarily due to the shift in trade and transport communications. By the 1910s, among the discursive dominants, the notion of the social and cultural identity of the North and the national significance of the monuments of its antiquity, as a heritage that was under the threat of extinction, was also entrenched.
A special group of "Northern" narratives were evidence left by artists – in travel notes, short stories, autobiographies. In particular, A.A. Borisov, V.V. Perepletchikov, I.E. Grabar’ and, earlier than the others, V.V. Vereshchagin wrote about the North. An essay of the latter "On the Northern Dvina. On the wooden churches" (1895), considered in the paper, is an example of the author's construction of the image of the region.
Poderes excepcionales. Suspender y limitar derechos fundamentales. A propósito de la STC 148/2021, de 14 de julio
Authors: Ródenas Calatayud Ángeles , Ruiz Manero Juan 
Published: October 2023

La sentencia del Tribunal Constitucional 148/2021, de 14 de julio, introduce una drástica modificación en la configuración del poder para declarar el estado de alarma respecto de su conformación originaria por parte del legislador orgánico. Para examinarlo, los autores comienzan exponiendo los diferentes argumentos del Tribunal Constitucional en la sentencia citada, vinculando cada uno de ellos con cada uno de los requisitos de la norma que confiere poder para declarar el estado de alarma. El corazón de la argumentación del TC se encuentra en el requisito de competencia material. La sentencia citada es objeto por parte de los autores de un análisis crítico que versa básicamente sobre la diferencia entre limitar y suspender un derecho fundamental, lo que a su vez constituye la piedra angular de la argumentación del TC. A juicio de los autores, la declaración del estado de alarma por parte del Consejo de Ministros en fecha 14 de marzo fue una medida claramente constitucional, puesto que encaja perfectamente con lo que sería una reconstrucción adecuada de lo que supone una limitación de un derecho fundamental.
DINAMIKA OVARIUM SAPI ENDOMETRITIS YANG DITERAPI DENGAN GENTAMICINE, FLUMEQUINE DAN ANALOG PROSTAGLANDIN F2 ALPHA (PGF2α) SECARA INTRA UTERUS
Authors: Melia Juli , A Amrozi , ITA TumbelakaLigaya Ligaya 
Published: October 2023

Penelitian ini bertujuan mengetahui efektivitas pengobatan endometritis dengan menggunakan kombinasi antibiotik (gentamicine,
flumequine) dan analog prostaglandin F2 alfa (PGF2α) berdasarkan pengamatan dinamika ovarium dengan metode ultrasonografi (USG). Enam
ekor sapi endometritis dibagi dalam 2 kelompok perlakuan. Kelompok I (K1, n= 3) diterapi dengan 250 mg Gentamicine, 250 mg Flumequine,
dan 12,5 mg PGF2α secara intra-uterus. Kelompok II (K2, n= 3) diterapi menggunakan antibiotik dengan dosis dan cara pemberian yang sama
seperti pada Kelompok I. Hasil pengamatan terhadap sapi-sapi endometritis K1 dan K2 memperlihatkan rataan panjang siklus estrus selama 18
hari. Hasil analisis statistik menunjukkan tidak ada perbedaan yang nyata (P>0,05) terhadap kelas folikel pada kedua kelompok perlakuan.
Folikel besar (DF) dan folikel besar kedua (SF) pada ke-3 gelombang folikel yang muncul tidak memperlihatkan perbedaan yang nyata antara K1
dan K2 (P>0,05), tetapi terdapat perbedaan yang nyata (P
11. Diagnostic surra (Trypanosoma evansi) on Buffalo Slaughtered in Banda Aceh and Aceh Besar Slaughterhouses Based on Card Agglutination Test for Trypanosoma evansi (CATT)
Authors: Athaillah Farida , Amira Kartika , Fahrimal Yudha 
Published: October 2023

This study aims to detect the presence of parasites indirectly by looking at antibodies to Trypanosoma evansi by using the method of Card Agglutination Test for Trypanosoma evansi (CATT). A total of 50 heads of buffaloes cut at Banda Aceh and Aceh Besar Slaughterhouses were taken blood for examination at the Parasitology and Research Laboratory of the Faculty of Veterinary Medicine of Syiah Kuala University. The principle of the CATT method is to look at the bonds between antibodies and antigens. Positive results are characterized by the formation of agglutination on the CATT paperboard. The score of agglutination reactions is divided into 5 categories, positive triple (+++) indicates agglutination is very strong, which means the possibility of newly infected animals, positive two (++) signifies strong agglutination, which means the animal may have been infected long enough, one (+) denotes moderate agglutination, meaning the animal has already been infected with T. evansi, dubious (±) denotes weak or dubious agglutination and, negative (-) signifies no agglutination. The results showed that from 50 samples examined, 14% (7/50) positive samples of agglutination were very strong, 24% (12/50) positive samples of strong agglutination, 48% (24/50) positive samples of moderate agglutination, and 0 negative samples T. evansi. The CATT method is very sensitive because 86% of the 50 buffaloes are tested positive or infected with T. evansi.
2. Effect of the Addition of Palm Kernel and Ammoniated Lemongrass Waste (Cymbopogon Nardus) on the Quality of Fresh Semen of Thin Tailed Sheep as a Partial Replacement of Basal Feed
Authors: Khairi Fitrah , Dini Cut Islami , Novita Cut Intan , Ayuti Siti Rani 
Published: October 2023

In this study, three sheep aged two years old with a bodyweight of 20-25 kg were used. The treatments consisted of R1 (10% palm kernel cake and ammoniated citronella waste), R2 (20% oil palm kernel cake and ammoniated citronella waste) and R3 (30% oil palm kernel cake and ammoniated citronella waste). Research design used was Latin Square Design with three treatments and three replications. The parameters of semen observed were macroscopic and microscopic quality which included color, odor, volume, consistency, pH, concentration, mass movement and individual motility. The results showed that the administration of palm kernel cake with concentrations of 10%, 20%, and 30% and ammoniated citronella waste had no significant effect (P0.05) on the quality of fresh thin-tailed sheep's semen both macroscopically and microscopically. The semen had an average volume of 0.62 ml, creamy in color, had a characteristic as semen odor, thick in consistency and has a normal pH of 6.89. Microscopically, it had average concentration of 1809x106/ml, average mass movement of ++, and average individual motility of 57.57%. Based on the results, the administration of palm kernel cake and ammoniated citronella waste does not affect the quality of the fresh semen of thin-tailed sheep, both macroscopically and microscopically.
Resistance Testing of Salmonella sp. Isolated from Broiler Chicken against Antibiotics
Authors: Syafitri Martiana , Erina Erina , AK M Daud , Ferasyi Teuku Reza , Hamzah Abdullah , Nazaruddin Nazaruddin , Ismail Ismail 
Published: October 2023

Antibiotic resistance has become a global problem, this happens because strains of bacteria in the body are resistant to antibiotics, one of which is caused by improper use. This study aims to determine the resistance of Salmonella sp. isolated from broiler chickens to antibiotics. The method used for this study is the Kirby Bauer disc diffusion method. The research samples were eight isolates from broiler chickens collected by the Laboratory of Microbiology, Faculty of Veterinary Medicine, Universitas Syiah Kuala. This study used antibiotics amoxicillin, streptomycin, chloramphenicol, ciprofloxacin, gentamicin, and tetracycline. The data obtained are processed descriptively. The results showed five isolates (62.5%) showed multidrug resistance and very high levels of resistance to antibiotics from eight samples tested, namely tetracycline 87.5% (7/8), chloramphenicol 75% (6/8), amoxicillin 62.5% (5/8), and streptomycin 62.5% (5/8). Antibiotics that are still sensitive are gentamicin 62.5% (5/8) and ciprofloxacin 50% (4/8). Therefore, it can be concluded that Salmonella sp. has been resistant to several types of antibiotics.
Innovative Solution to Stop the Flare at the Complex Gas Treatment Unit in Six Months. Case Study
Authors: Ablaev Anton , Ruban Konstantin , Zozulya Andrey 
Published: October 2023

Abstract
Due to the fact that about 150 billion m3 of associated petroleum gas is burned annually globally by oil and gas companies cause, it is not the main product and specialization for operators, a technology for disposing of flare equipment and using associated petroleum gas as an additional product of production was proposed on the basis of the existing enterprise.
Initially, the company's project involved burning part of the gas on flares, which led to environmental pollution and loss of product. Company evaluated the profitability and technical feasibility of a new project for the disposal of flares, which showed positive results.
As part of the project to switch from flaring of associated petroleum gas to its processing, design, selection and purchase of equipment was carried out, which led to the technical re-equipment of the existing enterprise. After the construction, implementation and launch of this technology, additional gas appeared in production, from which useful fractions were later isolated in the form of liquefied petroleum gas (LPG). Since the mineral extraction tax (MET) If the product was already paid, the resulting product was not subject to MET and excise taxes, which led to an increase in production profits. As a result of eliminating the waste of a valuable non-renewable resource due to flaring reduction and company received an additional production product, which was later completely processed and sent to the market.
During period of project 30 000 tons of CO2 emissions into the atmosphere was reduced, and in addition to the profit from the initial gas production, the company received additional profit from the production and sale of liquefied petroleum gas.
Enhancing Bioremediation of Petroleum-Contaminated Soil Using Rhamnolipids: A Combined Laboratory and Field Study
Authors: Ni Pan , Ren Yonglin Ginger , Brown Derick G. , Ayres Kris 
Published: October 2023

Abstract
Hydrocarbon spills can occur at various stages of the oil and gas exploration and production workflow. It would be beneficial to be able to treat these spills on-site to avoid more expensive excavation and incineration processes. This study aims to optimize the use of rhamnolipid biosurfactants for enhancing the bioremediation of hydrocarbon-contaminated soil. The goal of this work was to explore the effects of rhamnolipid application on hydrocarbon degradation rate under both laboratory and field conditions, and to examine the effects of this treatment on the indigenous soil microorganism population. The results have demonstrated the potential for rhamnolipids to enhance the remediation of petroleum hydrocarbons in contaminated soils. The laboratory experiments showed that the application of rhamnolipids at above 0.5g/kg was effective in increasing bacteria activity in the soil. Knowledge from the lab tests was used to design the field experiments, and the respirometry results were combined with biological stoichiometric calculations to determine the appropriate nutrient loading for the field site. Lab tests are a critical prerequisite for understanding bioremediation mechanisms for a particular contaminated site and designing an effective field treatment program. The field results correlated with the laboratory respirometry results, and the field study confirmed that the application of rhamnolipid in combination with ammonium chloride as the nitrogen source was able to improve the overall health of the soil. Bacterial analysis demonstrated that addition of rhamnolipid enriched the soil in Pseudomonas and Serratia bacterial species, which are known hydrocarbon degraders. Additionally, these strains were shown to degrade rhamnolipid, and this affirms the beneficial aspect that applied rhamnolipid won't accumulate and persist in the environment. Overall, this work provides insight into the combination of laboratory and field studies when using rhamnolipids to enhance bioremediation of contaminated soils.