bluuebunny/crossref_metadata_2025_split huggingface dataset:
Two New Successive Addition Arguments
Authors: Dagher Ibrahim 
Published: February 2024

AbstractOne of William Lane Craig's key arguments for the finitude of the past is the Successive Addition Argument (SAA). Malpass (2021) has recently developed a novel challenge to the SAA, utilising a thought experiment from the work of Fred Dretske, which is meant to show that it is possible to count to infinity, to argue that there is a counterexample to the SAA's second premise. In this paper, I contend that the Malpass‐Dretske counterexample should not worry advocates of the SAA. First, I argue that one objection Malpass considers—the Potential Infinite Objection—reveals an interesting fact: the SAA's second premise is unnecessarily strong and can be weakened whilst still yielding the same conclusion. Second, I show how another one of the objections considered by Malpass—the Accumulation Objection—is successful, provided some clarification to the SAA's premises. The upshot of both analyses is that we generate two ‘new’ Successive Addition arguments that not only move the dialectic forward, but shed light on deeper assumptions and motivating intuitions concerning the Kalām.
Migration mortality in birds
Authors: Newton Ian 
Published: February 2024

Bird migration is one of the greatest wildlife spectacles, producing massive global changes in the distributions of birds twice each year. To understand the evolution of this phenomenon, it is important to know the costs of these journeys in terms of the mortality they impose. The use of mark/re‐sighting and tracking studies has now made it possible, for some bird species, to separate mortality during migration from mortality during stationary periods. This paper aims to assess this information, based mainly on 31 published studies, most of which concern long‐distance migrations of passerines, large waterfowl and raptors. Most of these studies revealed that mortality rates were greater during migration than at other times – in some species more than 20 times greater. Overall, on the basis of median values, mortality per unit time during autumn journeys was about 3.0 times greater than mortality during stationary periods, during spring journeys about 6.3 times greater, and during autumn and spring journeys combined 4.4 times greater. The greater overall mortality on spring journeys was largely associated with more adverse wind conditions in spring than in autumn. High mortality rates were especially evident in birds crossing large ecological barriers, such as the Sahara Desert or the Gulf of Mexico, and were higher in that part of their journey than when crossing more benign terrain. There was no increase in mortality during migration in the adults of some long‐lived species with high annual survival and predominantly overland journeys; for these birds, much larger samples of year‐round tracked individuals will be needed to reveal any seasonal variations in mortality. Within certain species, birds that travelled long distances experienced greater mortality over the journey than those that travelled short distances, but in other species no such relationship was found. In species in which adults and juveniles were followed over the same journey, juveniles showed greater mortality. To judge from other studies, this difference could be attributed to the inexperience of juveniles, their lower feeding rates and flight efficiency, greater vulnerability to hazards such as weather and predation, or more frequent navigational errors. Broadly speaking, the risks of migration vary with features of the birds themselves, with the terrain to be crossed and with weather at the time. It may be assumed that migration persists in the long term because the costs (in terms of associated mortality) are more than offset by the benefits of breeding and wintering in different areas (in terms of improved overall survival and breeding success). To provide further understanding of migration mortality, suggestions are made on the types of studies required and on how they could best be conducted.
A rapidly growing nodule on the face during pregnancy
Authors: Lai Michela , Piana Simonetta , Mirra Marica , Raucci Margherita , Pampena Riccardo , Longo Caterina 
Published: February 2024

AbstractIt is well known that adnexal skin tumors can simulate other cutaneous neoplasia and that various types of benign and malignant skin tumors can develop or modify during pregnancy. Here, we report a case of trichoblastoma mimicking a keratoacanthoma arising in a nevus sebaceous during pregnancy. Given its unique clinical and dermoscopic features, this case highlights the pivotal role of clinicopathological correlation in the diagnosis of adnexal tumors with an atypical clinical presentation.
Enhancing ice cream qualities with novel rice husk cellulose nanocrystal applications
Authors: Samsalee Namfon , Meerasri Jitrawadee , Sothornvit Rungsinee 
Published: February 2024

SummaryCellulose nanocrystals derived from rice husk (CNC) using a chemical method combined with high‐pressure homogenisation, were investigated for their application in ice cream formulations. The physicochemical and sensory properties of ice cream with CNC at three different concentrations (0%, 0.15%, and 0.30% wt.) and two levels of whipping cream as fat content (5% and 10% wt.) were studied. The results indicate that increased CNC concentration enhanced the overrun and viscosity of the ice cream samples. Furthermore, 10% fat ice cream with 0.30% CNC exhibited higher total phenolic content and antioxidant activity compared to the others. The hardness and melting rate of the ice cream samples tended to decrease with higher fat levels and CNC concentrations. Moreover, CNC helped to improve the quality of low‐fat ice cream while still maintaining satisfactory sensory properties. Therefore, CNC has the potential as a stabiliser for ice cream to improve its overall properties.
Avocado leaf‐waste management: drying technology and quality of leaf herbal teas of different varieties cultivated in the Mediterranean area
Authors: Cincotta Fabrizio , Merlino Maria , Condurso Concetta , Miller Anthea , Torre Marco , Verzera Antonella 
Published: February 2024

SummaryAvocado production is globally increasing, and wastes and by‐products are becoming an emergent problem for its sustainability. The research aims to valorise the avocado waste leaves, giving them new challenges and opportunities in the herbal tea sector. In this regard, leaves of different avocado varieties cultivated in the Mediterranean area and different drying technologies were considered for the preparation of herbal teas; chemical and sensory analyses have been carried out. The results demonstrated differences in the composition, antioxidant activity, aroma volatiles, sensory features, and thus on the consumers' acceptability of the avocado herbal teas in relation to the variety and the drying technology. Herbal teas prepared with microwave‐dried leaves of Fuerte and Bacon varieties were the most appreciated by consumers for their sweet taste and anise‐like odour. The data showed the possibility of using avocado leaf waste for new herbal teas, evidencing the influence of the drying technology and variety on the functional and sensory features of the developed product. In this context, the approach here applied resulted fundamental to orientate the development of new sustainable and healthy herbal tea that meets consumers' demands.
Improving the encapsulation of β‐carotene by nanoliposomes via potato starch/whey protein coating
Authors: Gu Jinhui , Xu Tao , Pan Min‐hsiung , Chiou Yi‐shiou , Ding Baomiao 
Published: February 2024

SummaryThe ability of nanoliposomes (NLs) to encapsulate β‐carotene synergistically improved via the potato starch (PS)/whey protein (WP) coating was investigated. The encapsulation efficiency of PS‐/WP‐coated NL (SP‐NL) increased to above 80% compared to that of NL, PS‐coated NL, and WP‐coated NL. It manifested that the ability of NL to encapsulate β‐carotene was significantly enhanced after coating with PS/WP. The encapsulation ability of SP‐NL was also influenced by environmental factors (pH, temperature, and ionic strength). Moreover, the storage stability of NL after complexation with PS/WP was effectively enhanced compared to that of NL, PS‐coated NL, and WP‐coated NL. TEM images showed that SP‐NL was fairly spherical, and SP‐NL mainly ranged between 100 nm and 500 nm in size. Zeta‐potential and particle size indicated that the dispersion of SP‐NL was highly stable, and electrostatic forces played a vital role in the stability. Furthermore, the fluorescence polarisation of DPH demonstrated that the decrease in membrane fluidity of NL after PS/WP coating was more obvious from 5.28 to 4.05 compared with that of NL after PS or WP coating, indicating that PS/WP was more effective in increasing the rigidity of the phospholipid layer and improving the structure of the bilayer. The present study suggests that PS/WP coating on NL can be an effective strategy to improve the ability of NL to encapsulate β‐carotene and may provide some theoretical support for the development of an effective delivery system for bioactive substances.
Functional properties and anti‐hyperglycaemia capacity of Satureja essential oil: stabilisation of essential oil in gelatin and physico‐chemical properties characterisation
Authors: Obeidnejad Elham , Kavoosi Gholamreza , Saharkhiz Mohammad Jamal , Niakousari Mehrdad 
Published: February 2024

SummaryThis work presents the impact of Satureja essential oil (SEO) on the mRNA generation of NFR2, NF‐kB, and NOX (NADH oxidase) in the macrophage stimulated with hyperglycaemia. Furthermore, SEO incorporated into gelatin particles and physico‐chemical properties were investigated. The major variation between different constituents of SEO was found in carvacrol (35.9%–87.6%) and γ‐terpinene (0.43%–33.9%). Different SEO with different constituents exhibited comparable antioxidant capacity (IC50 = 0.170–0.215 mg mL−1), anti‐linoleic acid oxidation (IC50 = 0.137–0.195 mg mL−1), anti‐lecithin oxidation (IC50 = 0.126–0.134 mg mL−1), anti‐starch oxidation (IC50 = 0.155–0.199 mg mL−1), anti‐protein oxidation (IC50 = 0.166–0.211 mg mL−1), anti‐amylase capacity (IC50 = 0.202–0.230 mg mL−1), and anti‐lipase capacity (IC50 = 0.24–0.260 mg mL−1). Hyperglycaemia stimulates NOX, NFR2, NF‐kB, and hydrogen peroxide in macrophages. SEO (at 0.03 and 0.06 mg mL−1) decreased NOX and NF‐kB activity and hydrogen peroxide and increased NFR2 in hyperglycaemia‐stimulated macrophages. The physio‐chemical parameters of gelatin dispersion were electrical conductivity (1095 microsiemens cm−1), osmolarity (176 milliosmol kg−1), surface tension (42 mN m−1), zeta potential (−40 mV), particle size (123 nm), particle size distribution (0.18), and viscosity (3.47 mPa.s). The techno‐functional parameters of gelatin particles were water content (10.4%), water solubility (83%), water swelling (138%), hygroscopicity (35%), hydrophobicity (6.8 μg g−1), emulsification activity (62%), emulsification stability (52%), foam activity (49%), foam stability (42%), water‐holding capacity (4.5 g g−1), and oil‐holding capacity (2.4 g g−1). SEO causes minor changes in the techno‐functional and physico‐chemical properties of gelatin. The current investigation introduces gelatin/SEO as a possible functional ingredient for bioactive food products for the treatment of diabetes, oxidative stress, and inflammation.
Effect of ingredients on cooking quality, textural properties, and microstructure of fresh mung bean by‐product gluten‐free pasta
Authors: Adiba Iffadhiya Fathin , Sae‐tan Sudathip , Katekhong Wattinee , Ritthiruangdej Pitiporn , Chaveesuk Ravipim , Ratanasumawong Savitree 
Published: February 2024

SummaryMung bean by‐product (MBB), containing high protein and dietary fibre, was selected as the main ingredient to make fresh gluten‐free pasta. Effects of MBB flour, egg white powder (EWP) and water on pasta quality were investigated by extreme vertices mixture design. Seven formulations of MBB pasta were evaluated for colour, protein content, dietary fibre, cooking quality and textural properties. All MBB pasta formulations had significantly higher protein content and dietary fibre than semolina pasta. Higher EWP content increased optimum cooking time, firmness, tensile strength and elongation (P ≤ 0.05) and decreased cooking loss. Scanning electron micrographs showed that the EWP created a strongly continuous protein network. An increase in water reduced cooking time and firmness but increased cooking loss (P ≤ 0.05). Firm and elastic cooked MBB pasta was obtained under conditions of high EWP and low moisture content.
“Do the right thing”: Immigrant perspectives of social worker support in the United States
Authors: Rai Abha , Held Mary Lehman , Huslage Melody , Galvez Eliza , Ayalew Yigermal Demissie , Siksay Leia 
Published: February 2024

AbstractSocial workers play a distinctive role in serving all communities, especially immigrants. Heightened immigrant stress and deteriorating well‐being have been reported amid recent anti‐immigrant socio‐political climate. Given the unique challenges of immigrants, they have distinct needs. In our study, we utilize data from a larger study including a sample of first‐ and second‐generation immigrants, to understand “How can social workers support immigrant communities?” In total, N = 265 participants responded to this prompt. We employed a content analysis approach to analyze participant responses. Our analysis yielded four main themes: (1) Resources for immigrants, (2) Doing right by immigrants, (3) Advocacy, and (4) Understanding immigrants. Our findings are timely in highlighting the diverse perspectives about immigrant needs in the current socio‐political climate. Study findings have implications for social workers as well as service providers/agencies that engage with immigrants.
Pla2g5 contributes to viral‐like‐induced lung inflammation through macrophage proliferation and LA/Ffar1 lung cell recruitment
Authors: Koganesawa Masaya , Dwyer Daniel F. , Alhallak Kinan , Nagai Jun , Zaleski Kendall , Samuchiwal Sachin , Hiroaki Hayashi , Nishida Airi , Hirsch Thomas I. , Brennan Patrick J. , Puder Mark , Balestrieri Barbara 
Published: February 2024

AbstractMacrophages expressing group V phospholipase A2 (Pla2g5) release the free fatty acid (FFA) linoleic acid (LA), potentiating lung type 2 inflammation. Although Pla2g5 and LA increase in viral infections, their role remains obscure. We generated Pla2g5flox/flox mice, deleted Pla2g5 by using the Cx3cr1cre transgene, and activated bone marrow‐derived macrophages (BM‐Macs) with poly:IC, a synthetic double‐stranded RNA that triggers a viral‐like immune response, known Pla2g5‐dependent stimuli (IL‐4, LPS + IFNγ, IL‐33 + IL‐4 + GM‐CSF) and poly:IC + LA followed by lipidomic and transcriptomic analysis. Poly:IC‐activated Pla2g5flox/flox;Cx3cr1cre/+ BM‐Macs had downregulation of major bioactive lipids and critical enzymes producing those bioactive lipids. In addition, AKT phosphorylation was lower in poly:IC‐stimulated Pla2g5flox/flox;Cx3cr1cre/+ BM‐Macs, which was not restored by adding LA to poly:IC‐stimulated BM‐Macs. Consistently, Pla2g5flox/flox;Cx3cr1cre/+ mice had diminished poly:IC‐induced lung inflammation, including inflammatory macrophage proliferation, while challenging Pla2g5flox/flox;Cx3cr1cre/+ mice with poly:IC + LA partially restored lung inflammation and inflammatory macrophage proliferation. Finally, mice lacking FFA receptor‐1 (Ffar1)‐null mice had reduced poly:IC‐induced lung cell recruitment and tissue macrophage proliferation, not corrected by LA. Thus, Pla2g5 contributes to poly:IC‐induced lung inflammation by regulating inflammatory macrophage proliferation and LA/Ffar1‐mediated lung cell recruitment and tissue macrophage proliferation.
Cardiac implantable electronic devices in female patients: Esthetic, breast implant, and anatomic considerations
Authors: Salinas Cristina A. , Ezzeddine Fatima M. , Mulpuru Siva K. , Asirvatham Samuel J. , Sharaf Basel A. 
Published: February 2024

AbstractIntroductionThe implantation of a cardiac implantable electronic device (CIED) can have esthetic and psychological consequences on patients. We explore a heart team model for care coordination and discuss esthetic approaches for improved cosmetic outcomes in patients undergoing (CIED)‐related procedures or de novo implantation.MethodsPatients undergoing CIED surgery for approved indications between June 2015 and June 2022 were identified. Patients were included when surgical care was provided by a collaborative relationship between the primary electrophysiologist and the plastic surgeon. Patient demographics, details of the surgical procedure, information on breast implants, complications, and outcomes related to cosmesis were recorded.ResultsTwenty‐two female patients were included in this study. The mean age was 50.2 ± 18.2 years. The mean follow‐up duration was 2.2 ± 5.5 months. The top two indications for the procedure included CIED generator change (n = 9, 41%) and implantable cardioverter‐defibrillator (ICD) implantation (n = 7, 32%). The most common reasons for involving plastic surgery in the procedure included surgery near breast implants (n = 10, 45%) and device displacement or discomfort (n = 8, 36%). CIED pocket position was prepectoral in 10 cases (45%), subpectoral in 11 patients (50%), and intramuscular in one patient (4.5%). The majority of the patients (20, 91%) had cosmetically acceptable results postprocedure. One patient (4.5%) had breast asymmetry on the CIED side, and another continued to have skin erosion over the CIED and leads.ConclusionA heart team approach incorporating the expertize of cardiac electrophysiology and plastic surgery is essential for providing optimal care for patients with breast implants and patients requesting esthetic appeal.
EU Geoeconomic Power in the Clean Energy Transition
Authors: Jerzyniak Tomasz , Herranz‐Surrallés Anna 
Published: February 2024

AbstractThe energy transition is affected by a ‘double geopoliticisation’: global competition for hydrocarbons has increased, due to the sudden turmoil in the energy markets, whilst the urgency to clean energy transition has exacerbated competition for green technological leadership. This article investigates whether the EU has adapted its goals and instruments to these intertwined geopoliticisation pressures and, if so, under what conditions has it been able to wield geoeconomic power. Using Barnett and Duvall's taxonomy of power, this article argues that geoeconomic power presupposes a shift from diffuse to direct forms of power and theorises the factors that facilitate or constrain the EU's ability to exercise this type of power. This article finds that the EU has significantly transformed the goals and instruments of its external energy policy. Yet the extent of its geoeconomic power depends on a combination of often‐overlooked domestic enabling factors and the external geopolitical environment.
Truncated GPNMB, a microglial transmembrane protein, serves as a scavenger receptor for oligomeric β‐amyloid peptide1‐42 in primary type 1 microglia
Authors: Kawahara Kohichi , Hasegawa Takuya , Hasegawa Noa , Izumi Taisei , Sato Koji , Sakamaki Toshiyuki , Ando Masayuki , Maeda Takehiko 
Published: February 2024

AbstractGlycoprotein non‐metastatic melanoma protein B (GPNMB) is up‐regulated in one subtype of microglia (MG) surrounding senile plaque depositions of amyloid‐beta (Aβ) peptides. However, whether the microglial GPNMB can recognize the fibrous Aβ peptides as ligands remains unknown. In this study, we report that the truncated form of GPNMB, the antigen for 9F5, serves as a scavenger receptor for oligomeric Aβ1‐42 (o‐Aβ1‐42) in rat primary type 1 MG. 125I‐labeled o‐Aβ1‐42 exhibited specific and saturable endosomal/lysosomal degradation in primary‐cultured type 1 MG from GPNMB‐expressing wild‐type mice, whereas the degradation activity was markedly reduced in cells from Gpnmb‐knockout mice. The Gpnmb‐siRNA significantly inhibits the degradation of 125I‐o‐Aβ1‐42 by murine microglial MG5 cells. Therefore, GPNMB contributes to mouse MG's o‐Aβ1‐42 clearance. In rat primary type 1 MG, the cell surface expression of truncated GPNMB was confirmed by a flow cytometric analysis using a previously established 9F5 antibody. 125I‐labeled o‐Aβ1‐42 underwent endosomal/lysosomal degradation by rat primary type 1 MG in a dose‐dependent fashion, while the 9F5 antibody inhibited the degradation. The binding of 125I‐o‐Aβ1‐42 to the rat primary type 1 MG was inhibited by 42% by excess unlabeled o‐Aβ1‐42, and by 52% by the 9F5 antibody. Interestingly, the 125I‐o‐Aβ1‐42 degradations by MG‐like cells from human‐induced pluripotent stem cells was inhibited by the 9F5 antibody, suggesting that truncated GPNMB also serve as a scavenger receptor for o‐Aβ1‐42 in human MG. Our study demonstrates that the truncated GPNMB (the antigen for 9F5) binds to oligomeric form of Aβ1‐42 and functions as a scavenger receptor on MG, and 9F5 antibody can act as a blocking antibody for the truncated GPNMB.image
Geographic disparities in late HIV diagnoses in Tennessee: Opportunities for interventions in the rural Southeast
Authors: Gibas Kevin M. , Rebeiro Peter F. , Brantley Meredith , Mathieson Samantha , Maurer Laurie , Pettit April C. 
Published: February 2024

AbstractPurposeIncident HIV remains an important public health issue in the US South, the region leading the nation in HIV incidence, rural HIV cases, and HIV‐related deaths. Late diagnoses drive incident HIV and understanding factors driving late diagnoses is critical for developing locally relevant HIV testing and prevention interventions, decreasing HIV transmission, and ending the HIV epidemic.MethodsRetrospective cohort study utilizing Tennessee Department of Health (TDH) surveillance data and US Census Bureau data. Adults of ≥18‐year old with a new HIV diagnosis between January 1, 2015 and December 31, 2019 identified in the TDH electronic HIV/AIDS Reporting System were included. Individuals were followed from initial HIV diagnosis until death, 90 days of follow‐up for outcome assessment, or administrative censoring 90 days after study enrollment closed.FindingsWe included 3652 newly HIV‐diagnosed individuals; median age was 31 years (IQR: 25, 42), 2909 (79.7%) were male, 2057 (56.3%) were Black, 246 (6.7%) were Hispanic, 408 (11.2%) were residing in majority‐rural areas at diagnosis, and 642 (17.6%) individuals received a late HIV diagnosis. Residents of majority‐rural counties (adjusted risk ratios [aRR] = 1.39, 95% confidence intervals [CI]: 1.16–1.67) and Hispanic individuals (aRR = 1.87, 95% CI: 1.50–2.33) had an increased likelihood of receiving a late diagnosis after controlling for race/ethnicity, age, and year of HIV diagnosis.ConclusionsRural residence and Hispanic ethnicity were associated with an increased risk of receiving a late HIV diagnosis in Tennessee. Future HIV testing and prevention efforts should be adapted to the needs of these vulnerable populations.