bluuebunny/crossref_metadata_2025_split huggingface dataset:
Methane and Nitrous Oxide Emissions From an Anthropogenically Transformed Lake (Lake Licheńskie, Poland)
Authors: Woszczyk M. , Schubert C. J. 
Published: December 2023

AbstractFor over 50 years Lake Licheńskie (LLi), central Poland, has been involved in the cooling system of two power plants (PP). Owing to the discharge of cooling waters the lake was prone to considerable environmental changes which involved its thermal structure, mixing regime and water parameters. In this study we investigated how the man‐made transformations affected greenhouse gas emissions (GHG; CH4 and N2O) from the lake. The GHG emissions in Lake Licheńskie were monitored at the deepest site from December 2014 to November 2015 and between March 2022 and February 2023. The values obtained were compared to reference lakes encompassing 10 natural and undisturbed inland and coastal lakes in Poland. Our results revealed that LLi was a net source of CH4 and N2O to the atmosphere but the fluxes were low. The mean annual diffusive fluxes were 0.21–0.38 mmol·m−2 d−1 for CH4 and 4.90–7.40 μmol·m−2 d−1 for N2O. The CH4 emissions were significantly lower than in most of reference lakes, while the N2O emissions were comparable. Therefore, the human intervention resulted in reduction of CH4 release from LLi but it had minor effect on the N2O. The most likely reason for the low direct fluxes of GHGs from the surface waters was the high flushing rate of the lake and export of dissolved gases to adjacent lakes and canals. Hence, the overall emission from the connected lake and canal system was not mitigated by the man‐made changes to the lake system.
Compost Amendment to a Grazed California Annual Grassland Increases Gross Primary Productivity Due To a Longer Growing Season
Authors: Fenster Tommy L. D. , Torres Isabel , Zeilinger Adam , Chu Housen , Oikawa Patty 
Published: December 2023

AbstractCompost amendment to rangelands is a proposed nature‐based climate solution to increase plant productivity and soil carbon sequestration. However, it has not been evaluated using quasicontinuous ecosystem‐scale measurements. Here, we present the first study to utilize eddy covariance and footprint partitioning to monitor carbon exchange in a grassland with and without compost amendment, monitoring for 1 year before and 1 year after treatment. Compost amendment to an annual California grassland was found to enhance net ecosystem removal of carbon. Our study confirmed that compost‐amended grasslands, similar to nonamended grasslands, are net carbon sources to the atmosphere; however, the amendment appears to be slowing down the rate at which these ecosystems lose carbon by 0.71 Mg C ha−1 per growing season. Digital repeated imagery of the canopy revealed that compost‐amended grasslands experienced an earlier green‐up, resulting in an overall longer growing season by >60 days. Notably, we did not detect significantly higher amounts of soil carbon in compost‐amended soils. High variability in soil carbon demands greater sampling replication in future studies. A longer growing season and higher productivity are hypothesized to be a result of greater availability of macronutrients and micronutrients in the top layer of soil (specifically nitrogen, phosphorus, and zinc).
Mother-newborn couplet care: Nordic country experiences of organization, models and practice
Authors: Klemming Stina , Lilliesköld Siri , Arwehed Sofia , Jonas Wibke , Lehtonen Liisa , Westrup Björn 
Published: December 2023

AbstractMother-Newborn Couplet Care is a concept and is defined as the provision of care for a sick or preterm newborn in close proximity to and coupled with the care for the mother from the birth of the infant and for as long as the mother needs hospital care. This concept of care requires system change in both obstetrics and pediatrics in terms of the planning and organization of care, equipment and design of units. Accordingly, strong leadership setting clear goals and emphasizing a culture of cohesive care, supported by targeted education and training is crucial to ensure high-quality care of all mother-newborn dyads without separation. We describe various organizational models of Mother-Newborn Couplet Care used in Sweden and Finland and implementation processes. We envision a future where newborns and mothers are always together, irrespective of medical needs, and form an inseparable center around which healthcare services and providers are organized.
Rare, but potentially risky, high individual increase of self-reported sexual arousal in men, who have committed sexual offenses against children, while being confronted with experimental sexual stimuli — a retrospective data analysis
Authors: Jordan Kirsten , Fromberger Peter , Müller Isabel , Wild Tamara Sheila Nadine , Müller Jürgen Leo 
Published: December 2023

AbstractThis data analysis was initiated to further understand the infrequent yet intense instances of sexual arousal and signs of decompensation that emerge after exposing men who have committed sexual offenses against children to experimental sexual stimuli. We analyzed retrospectively and exploratory data of a self-developed sexual arousal questionnaire (“Current-State-of-Emotions-Questionnaire”, CSEQ) with the following objectives: (i) examine subjective sexual arousal changes elicited during confrontation with experimental sexual stimuli, (ii) analyze these sexual arousal changes at an individual level to detect large responses, and (iii) ask for associations between large responses in sexual arousal and individual characteristics of participants, e.g., demographic, clinical, and criminological parameters. The sample consisted of 241 adult, male Germans, comprising four groups: Ten individuals who have committed sexual offenses against children and have been placed in forensic psychiatric facilities (ISOCFP), 31 non-hospitalized individuals with sexual interest in children (ISIC), eight individuals who have committed other offenses and have been placed in forensic psychiatric facilities (IOFP), and 192 individuals without sexual interest in children and offense histories (IWO). We found a significant increase in subjective sexual arousal after confrontation with sexual stimuli (three experiments: initial orientation: Z = −4.819, p < .001, sexual distractor task: Z = −2.954, p = .003, stimulus rating: Z = −6.899, p < .001). Up to 14.3% of participants indicated high sexual arousal values before, but mainly after the experiments, with 20.0% of ISOCFP, 12.9% of ISIC, 12.5% of IOFP, and 14.6% of IWO. ISOCFP and ISIC with high sexual arousal were more likely to be diagnosed with paraphilia (pedophilia) and/or affective disorders, and to receive anti-depressive treatment. We assume a higher emotional lability or/and reduced emotion regulation abilities in those individuals. A careful weighing up of anticipated scientific knowledge gain and a potentially, though rare, increased risk of recidivism or decompensation seems indispensable.
SARS-CoV-2 vaccination may improve anxious, insomnia and depressive symptoms among Chinese population aged 18–75 years during the COVID-19 pandemic
Authors: Zhang Xiaobo , Yue Qiang , Li Mingxia , Wu Chaoping , Zhou Lu , Cai Yang , Xu Jian 
Published: December 2023

AbstractPrevious studies have reported significant decreases in the incidence of mental health problems following SARS-CoV-2 vaccination. However, less relevant studies are published in China. We conducted a cross-sectional study involving Chinese adults aged 18–75 years with no known psychiatric diseases. The study used data from mental health of SARS-CoV-2 vaccinated and unvaccinated participants from May 2020 to July 2021.Three standardized scales, namely, the Generalized Anxiety Disorder-7 (GAD-7) for anxious symptoms, Patient Health Questionnaire-9 (PHQ-9) for depressive symptoms and Athens Insomnia Score-8 (AIS-8) for insomnia symptoms, as well as basic demographic questions were used. The hierarchical regression method was used for multivariate logistic regression analysis to explore the effects of SARS-CoV-2 vaccination on anxious, insomnia, and depressive symptoms. The results confirmed first that vaccinated participants experienced significantly lower anxious, insomnia, and depressive symptoms scores (P < 0.001) compared with unvaccinated participants. Second that vaccinated participants had a lower prevalence of anxious, insomnia, and depressive symptoms (P < 0.001). Third, after adjusting for potential confounders, we still observed a good correlation between vaccination and a reduced risk of anxious, insomnia, and depressive symptoms. The current study showed that SARS-CoV-2 vaccination may be helpful in improving anxious, insomnia, and depressive symptoms.
SIRT6 promotes metastasis and relapse in HER2-positive breast cancer
Authors: Andreani Cristina , Bartolacci Caterina , Persico Giuseppe , Casciaro Francesca , Amatori Stefano , Fanelli Mirco , Giorgio Marco , Galié Mirco , Tomassoni Daniele , Wang Junbiao , Zhang Xiaoting , Bick Gregory , Coppari Roberto , Marchini Cristina , Amici Augusto 
Published: December 2023

AbstractThe histone deacetylase sirtuin 6 (SIRT6) has been endowed with anti-cancer capabilities in many tumor types. Here, we investigate the impact of SIRT6-overexpression (SIRT6-OE) in Delta16HER2 mice, which are a bona fide model of HER2-positive breast cancer. After an initial delay in the tumor onset, SIRT6-OE induces a more aggressive phenotype of Delta16HER2 tumors promoting the formation of higher number of tumor foci and metastases than controls. This phenotype of SIRT6-OE tumors is associated with cancer stem cell (CSC)-like features and tumor dormancy, and low senescence and oxidative DNA damage. Accordingly, a sub-set of HER2-positive breast cancer patients with concurrent SIRT6-OE has a significant poorer relapse-free survival (RFS) probability than patients with low expression of SIRT6. ChIP-seq, RNA-seq and RT-PCR experiments indicate that SIRT6-OE represses the expression of the T-box transcription factor 3 (Tbx3) by deacetylation of H3K9ac. Accordingly, loss-of-function mutations of TBX3 or low TBX3 expression levels are predictive of poor prognosis in HER2-positive breast cancer patients. Our work indicates that high levels of SIRT6 are indicative of poor prognosis and high risk of metastasis in HER2-positive breast cancer and suggests further investigation of TBX3 as a downstream target of SIRT6 and co-marker of poor-prognosis. Our results point to a breast cancer subtype-specific effect of SIRT6 and warrant future studies dissecting the mechanisms of SIRT6 regulation in different breast cancer subtypes.
Influence of dynamic load and water on energy accumulation and dissipation in sandstone
Authors: Yang Yang , Xing Yulong , Fang Kailun , Wu Chao , Yang Kaiping , Xie Zhifeng , Wang Xianpeng , Sergey Nikolayevich Leonovich 
Published: December 2023

AbstractIn various engineering projects such as mineral extraction, hydropower resource utilization, railway construction, and geological hazard mitigation, rock engineering is often encountered. Furthermore, dynamic loads and moisture content exert notable influence on the energy transformation processes within rocks. Yet, the specific interplay of dynamic loading and water's impact on the energy conversion mechanism within the sandstone remains unexplored. To address this gap, this study conducted impact loading experiments on sandstone, elucidating the rock’s mechanical response under these conditions and unraveling the underlying energy conversion mechanisms. It was observed that the strength of sandstone exhibits a direct correlation with impact velocity. Moreover, employing energy calculation principles, we established a connection between moisture content and the sandstone’s internal energy conversion properties. The study also delved into the microscopic fracture mechanisms within the sandstone, ultimately concluding that both water content and dynamic loading have a significant impact on these microscopic fracture mechanisms.
Synergistic impact of arbutin and kaempferol-7-O-α-l-rhamnopyranoside from Nephelium lappaceum L. on whitening efficacy and stability of cosmetic formulations
Authors: Siridechakorn Ittipon , Pimpa Junsuda , Choodej Siwattra , Ngamrojanavanich Nattaya , Pudhom Khanitha 
Published: December 2023

AbstractFour flavonoid glycosides, namely quercetin-3-O-rhamnoside (1), kaempferol-3-O-β-d-glucopyranosyl (2), kaempferol-7-O-α-l-rhamnopyranoside (3), and kaempferol-3-O-β-d-glucopyranosyl-7-O-α-l-rhamnopyranoside (4), from Nephelium lappaceum L. seeds were evaluated for their efficacy against melanin inhibition in B16F10 melanoma cells and tyrosinase inhibition. Among them, kaempferol-7-O-α-l-rhamnopyranoside (3) displayed the highest potency in both activities without any significant cytotoxicity. The combination of compound 3 and arbutin in specific proportions demonstrated a synergistic effect (CI < 1) in inhibiting melanin production in B16F10 cells and tyrosinase inhibition. Additionally, a cosmetic formulation containing compound 3 and arbutin as active ingredients exhibited favorable stability under accelerated storage conditions. Quantitative analysis indicated that compound 3 and arbutin levels in the formulation were above 90% after one month of storage. Determination of the formulation's shelf life using the Q10 method, estimating it to be around 5.2 months from the date of manufacture. The synergy between arbutin and kaempferol-7-O-α-l-rhamnopyranoside (3) extracted from N. lappaceum substantially enhances both the whitening effectiveness and the stability of cosmetic formulations.
Association between elasticity of tissue and pain pressure threshold in the tender points present in subjects with fibromyalgia: a cross-sectional study
Authors: Navarro-Ledesma Santiago , Aguilar-García María , González-Muñoz Ana , Casas-Barragán Antonio , Tapia-Haro Rosa María 
Published: December 2023

AbstractFibromyalgia (FM) is a multicomponent illness and despite its worldwide prevalence, a complete understanding of its aetiology and pathogenesis remains unclear. The goal of the study is to analyze the level of association between elastic properties of tissue measured by strain elastography (SEL) and pain pressure threshold (PPT) in the characteristic painful points described in patients suffering from FM. This was a cross-sectional, observational study. A sample comprised of 42 subjects with FM was recruited from a private care centre. The occiput, low cervical, trapezius, supraspinatus, paraspinous, lateral pectoral, second rib, lateral epicondyle, medial epicondyle, gluteus, greater trochanter, knee, and anterior tibial PPTs were bilaterally assessed using a standard pressure algometer and elastic properties of tissue were evaluated by SEL. Linear regression analysis showed significant associations between SEL and dominant trapezius PPT (β = 0.487, 95% CI [0.045, 0.930], p = 0.032) after adjustments for the age, body mass index, and menopause status (higher SEL and higher pain sensitivity). No significant associations between SEL and the other PPTs variables were found in women diagnosed with FM. The PPT of the dominant trapezius is associated with SEL measurements in subjects suffering from FM. More studies are required to fully explain the underlying mechanisms.
Conversion of amino-terephthalonitriles to multi-substituted single benzene fluorophores with utility in bioimaging
Authors: Raghava Tanya , Chattopadhyay Anjan , Banerjee Subhadeep , Sarkar Nivedita 
Published: December 2023

Amine substitution of two ortho fluorine atoms of tetrafluoroterephthalonitrile through SNAr chemistry is easily achievable. But further fluorine substitution is only possible under forcing conditions, yielding valuable fluorophores for bioimaging.
Tuning the number and position of triphenylamine substituents on a benzo[b]furan core to achieve high-efficiency deep-blue and blue emitters
Authors: Luo MeiTing , Wu MingXin , Zhang BoHua , Wang XinYe , Chen Yi , Jia QingYu , Wang Dongdong , Gou Lei , Wu Zhaoxin 
Published: December 2023

The deep-blue to blue emitters, 56dTPA-BF, 356tTPA-BF and 2356fTPA-BF were successfully achieved by using benzo[b]furan as central skeleton. The 2356fTPA-BF shows the maximum EQE of 5.32/3.42% with emission peak of 448 nm in doped/non-doped devices.
Speech-Language Pathologists' Approach to Alternative Access for Augmentative and Alternative Communication for Children With Motor Impairments
Authors: Sowers Dawn J. , Wilkinson Krista M. 
Published: December 2023

Purpose:
This study examined the processes that speech-language pathologists (SLPs) use during an augmentative and alternative communication (AAC) assessment with children with motor impairments to determine alternative access solutions. These children often are the most vulnerable to a poor fit of their AAC system, which alternative access is an integral part. Although there is an abundance of information as to what types of considerations should be made during these assessments, there is no guidance as to how the assessment is completed. The goal of this study is to build evidence about the process.

Method:
A collective case design was used to gain detailed insights into the decision-making process. Interviews and vignette responses were two components of the data collection. Each of the five SLPs, or cases, who participated in the study transcripts was analyzed in isolation as part of a within-case analysis. Once each SLP's process was understood, a cross-case comparison was completed to ascertain similarities or differences across the five.

Results:
The cross-case assertions are presented in this article. Although the SLPs individually reported a lack of defined process, a clear systemization became evident when considered collectively. The SLPs all focused on the child, isolated motor access skills, and used a process of experimentation over time to build their final recommendations.

Conclusions:
These results have implications for SLPs working with children with motor impairments who may benefit from AAC intervention. The shared framework can serve as a roadmap to other SLPs, especially those with less experience with these types of complex cases. The varying teaming approaches to support these cases are also discussed.
Determining the Linguistic Profile of Children With Rare Genetic Disorders
Authors: Espinosa-Mojica Ana Alejandra , Varo Varo Carmen 
Published: December 2023

Purpose:
Language studies on populations with rare genetic disorders are limited. Hence, there is little data on commonly found or expected developmental linguistic traits and cognitive mechanisms that may be impaired. Based on the hypothesis that there is a close connection between language and cognition and the relevance of specific genetic changes in the development of each, our goal was to provide linguistic data on relationships with other executive functioning mechanisms.

Method:
This study assessed language skills, communicative behaviors, and executive functions in four children, aged 7–9 years, with rare genetic disorders, using standardized protocols and tests.

Results:
The findings revealed different levels of language impairment and executive functioning problems in each case. The overall executive function index performance for each of the four cases studied was clinically significantly high, indicating executive dysfunction.

Conclusions:
The cases analyzed illustrate different types of atypical development that affect both language and other cognitive mechanisms and underscore the importance of executive skills and the various ways in which they are involved in diverse levels of language that might be affected to a greater or lesser degree in rare genetic disorders. In conclusion, we found that language dysfunction is a salient feature of the rare genetic disorders included in our study, although this is not necessarily true for all genetic disorders. Along with these conclusive results, we performed a qualitative analysis of the linguistic and cognitive components that enable functional communication in order to allow optimal interpretation of the data we have collected, laying the foundations for a more effective therapeutic approach.
The Effects of Classroom Acoustic Conditions on Teachers' Health and Well-Being: A Scoping Review
Authors: Mealings Kiri , Maggs Lisa , Buchholz Joerg M. 
Published: December 2023

Purpose:
Teachers spend a significant amount of time in classrooms, which can be noisy environments. The aim of this scoping review was to determine what is known from the literature about the effect of classroom acoustic conditions on teachers' health and well-being.

Method:
This scoping review followed the PRISMA-ScR (Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews) protocol. Four bibliographic databases were searched: ERIC, PubMed, Scopus, and Web of Science.

Results:
Thirty-three articles were deemed relevant for the review. The most studied health aspect was teachers' vocal health. The majority of results showed higher noise levels or a higher number of students have a negative effect on teachers' health and well-being (61% and 60%, respectively), while 39% showed a negative effect of longer reverberation times. Most other results showed no effect.

Conclusions:
These results show that poor classroom acoustic conditions can have a negative effect on teachers' health and well-being. Therefore, creating classrooms with good acoustic conditions and controlling noise is vital. Limitations are discussed, and future research to better understand the relationship between classroom acoustic conditions and teachers' health and well-being is proposed. This future research will help in understanding the acoustic conditions that are needed to optimize teachers' health and well-being in the classroom.
Systematic review of hematophagous arthropods present in cattle in France
Authors: Prudhomme Jorian , Depaquit Jérôme , Fite Johanna , Quillery Elsa , Bouhsira Emilie , Liénard Emmanuel 
Published: December 2023

The arrival of pathogens, whether zoonotic or not, can have a lasting effect on commercial livestock farms, with dramatic health, social and economic consequences. However, available data concerning the arthropod vectors present and circulating on livestock farms in France are still very imprecise, fragmentary, and scattered. In this context, we conducted a systematic review of the hematophagous arthropod species recorded on different types of cattle farms in mainland France (including Corsica). The used vector “groups” studied were biting flies, biting midges, black flies, fleas, horse flies, lice, louse flies, mosquitoes, sand flies, and ticks. A large number of documents were selected (N = 9,225), read (N = 1,047) and analyzed (N = 290), allowing us to provide distribution and abundance maps of different species of medical and veterinary interest according to literature data. Despite the large number of documents collected and analyzed, there are few data provided on cattle farm characteristics. Moreover, data on all arthropod groups lack numerical detail and are based on limited data in time and/or space. Therefore, they are not generalizable nor comparable. There is still little information on many vectors (and their pathogens) and still many unknowns for most studied groups. It appears necessary to provide new, updated and standardized data, collected in different geographical and climatological areas. Finally, this work highlights the lack of entomologists, funding, training and government support, leading to an increased risk of uncontrolled disease emergence in cattle herds.
Naturheilkunde und Integrative Medizin bei Cancer-Related Fatigue
Authors: Winkler Marcela 
Published: December 2023

SummaryTumorassoziierte Fatigue ist ein Phänomen, das viele Krebspatient*innen erleben. Sie zeichnet sich unter anderem durch Symptome wie Schwäche, übermäßiges Schlafbedürfnis, Erschöpfung, Reizbarkeit sowie Konzentrations- und Gedächtnisstörungen aus. Um die Beschwerden bei Fatigue zu lindern, eignen sich verschiedene Therapieansätze. Dazu zählen Sport und Bewegung, Entspannungsübungen zur Stressreduktion, Akupunktur und Akupressur sowie Mittel aus der Phythotherapie wie Mistel- oder Ginseng-Extrakt.