bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effect of high-quality nursing on neurological function psychological moods quality of life of elderly patients with stroke
Authors: Gao Na , Li Yaqiang , Sang Changru , He Jiale , Chen Congxia 
Published: October 2023

ObjectivesThe primary objective of the present investigation was to meticulously examine the efficacy of high-quality nursing care (HQN) on neurological restoration, amelioration of adverse psychological states, and augmentation of quality of life in geriatric patients diagnosed with acute cerebral infarction (ACI).MethodsA cohort of 240 patients, afflicted by ACI and admitted to our healthcare institution between February 2020 and March 2023, were incorporated into this longitudinal prospective analysis. Employing a random number table methodology, the patient cohort was bifurcated into a control group (n = 120) receiving conventional care and an observation group (n = 120) receiving HQN. Comparisons were conducted between the two cohorts concerning neurological functionality [as quantified by the National Institutes of Health Stroke Scales (NIHSS) and Barthel Index (BI) scores], psychological wellbeing [utilizing the Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) scores], overall quality of life [assessed via the Generic Quality of Life Inventory-74 (GQOLI-74) scores], and self-perceived burden [evaluated through the Self-Perceived Burden Scale (SPBS)]. Further assessments included patient satisfaction and incidence of complications, both in the pre- and post-interventional phases.ResultsPost-intervention, the observation group demonstrated superior outcomes compared to the control group, as evidenced by diminished NIHSS and SPBS scores and elevated BI metrics. Moreover, SAS and SDS scores in both groups manifested a decline post-intervention; however, the decrement was statistically more pronounced in the observation group (P &lt; 0.05). Similarly, all dimensions of GQOLI-74 showed an upward trend in both cohorts, yet the increase was significantly more substantial in the observation group (P &lt; 0.05). Furthermore, the observation group exhibited a reduced frequency of complications coupled with heightened levels of nursing satisfaction.ConclusionThe implementation of HQN in the geriatric population afflicted by ACI markedly enhances neurological recuperation, attenuates adverse psychological states, and ameliorates overall quality of life. The intervention is also associated with a diminution in complication rates and an increase in nursing satisfaction, thereby substantiating its clinical utility.
Comparison of adjuvant nab-paclitaxel plus gemcitabine, S-1 and gemcitabine chemotherapy for resectable pancreatic cancer: a real-world study
Authors: Li Haorui , Guo Yu , Sun Xugang , Lu Yang , Chang Shaofei , Wang Xiuchao , Gao Song , Gao Chuntao , Zhao Tiansuo 
Published: October 2023

BackgroundA survival benefit has been seen for both adjuvant nab-paclitaxel plus gemcitabine (AG) and S-1 chemotherapy compared to gemcitabine (GEM) for resectable pancreatic cancer in the APACT (2019) and JASPAC01 trials (2016), respectively. However, supporting evidence regarding the effectiveness of AG or S-1 compared to gemcitabine in real-world clinical practice remains lacking.MethodsOur study included all 246 pancreatic cancer patients who underwent surgical treatment and received postoperative adjuvant chemotherapy with AG, S-1, or GEM except for those meeting exclusion criteria (R2 resection, neoadjuvant therapy, or synchronous malignancy) at Tianjin Medical University Cancer Institute and Hospital from June 2015 to July 2021. The primary outcome was overall survival (OS) and recurrence-free survival (RFS).ResultsIn total, 246 patients were included, of whom 54(22%) received adjuvant AG, 103(41%) received adjuvant S-1, and 89(37%) received adjuvant GEM. Adjuvant S-1 was associated with a prolonged OS compared to GEM (median OS S-1 vs GEM: 27.0 vs 20.0 months; HR: 0.65, P = .016) and a significantly prolonged RFS compared to GEM (median RFS S-1 vs GEM: 20.0 vs 8.2 months; HR: 0.58, P = .002). After adjusting for known prognostic factors in multivariate Cox regression analysis, this survival benefit persists and is consistent in most subgroups in our subgroup analysis. However, no statistically significant differences in OS or RFS were seen between patients treated with AG and patients treated with GEM.ConclusionsIn this retrospective real-world study, adjuvant S-1 chemotherapy was associated with improved survival compared to GEM while no differences in OS or RFS were observed for AG compared to GEM.
Maternal vitamin D in pregnancy and infant's gut microbiota: a systematic review
Authors: Molani-Gol Roghayeh , Rafraf Maryam 
Published: October 2023

BackgroundAn infant's gut microbiome plays a vital role in their health, and various factors can impact their gut microbiota composition. This review aimed to summarize the current knowledge regarding the associations between maternal prenatal supplementation with vitamin D and the composition of infants' gut microbiota.MethodA comprehensive systematic search was done on Web of Science, Scopus, PubMed, ScienceDirect, and Google Scholar databases without date restrictions until December 2022 using relevant keywords. All relevant original articles in English were eligible for the present review.ResultsEight articles (two mice, three randomized clinical trials, and three cohort studies) were included in this review. The included mice studies reported that maternal prenatal vitamin D supplementation significantly affects the offspring's gut microbiome composition (such as enhancing the abundance of colonic Bacteroides). Moreover, the included cohort studies revealed a significant association between maternal supplementation with vitamin D during pregnancy and the infant's gut microbiome. However, one-third of clinical trials indicated that vitamin D levels in utero could influence the colonization of the microbial community in the infant's gut.ConclusionThe findings of this review revealed that maternal vitamin D supplementation during pregnancy was linked to an infant's gut microbiome and could impact their gut microbiota composition. However, more studies are warranted to confirm these results.
Volume overload impedes the maturation of sarcomeres and T-tubules in the right atria: a potential cause of atrial arrhythmia following delayed atrial septal defect closure
Authors: Dong Zhuoya , Chen Dian , Zheng Sixie , Wang Zheng , Li Debao , Xiao Yingying , Sun Sijuan , Ye Lincai , Qiu Lisheng , Hu Yuqing , Hong Haifa 
Published: October 2023

Introduction: Adult patients with atrial septal defects (ASD), the most common form of adult congenital heart disease, often die of arrhythmias, and the immaturity of cardiomyocytes contributes significantly to arrhythmias. ASD typically induces a left-to-right shunt, which then leads to the right atrium (RA) volume overload (VO). Whether or not VO contributes to RA cardiomyocyte immaturity and thereby causes arrhythmias in adult patients with ASD remains unclear.Methods: Here, we developed the first neonatal RA VO mouse model by creating a fistula between the inferior vena cava and abdominal aorta on postnatal day 7. RA VO was confirmed by increases in the mean flow velocity, mean pressure gradient, and velocity time integral across the tricuspid valve, and an increase in the RA diameter and RA area middle section.Results: We found that VO decreased the regularity and length of sarcomeres, and decreased the T-element density, regularity, and index of integrity of T-tubules in RA cardiomyocytes, suggesting that the two most important maturation hallmarks (sarcomere and T-tubules) of RA cardiomyocytes were impaired by VO. Accordingly, the calcium handling capacity of cardiomyocytes from postnatal day 21 (P21) RA was decreased by VO. VO caused a significant elongation of the PR interval. The expression of connexin 43 (Cx43) was decreased in RA VO. Moreover, gene ontology (GO) analysis of the downregulated genes in RA demonstrated that there was an abundance of enriched terms associated with sarcomeres and T-tubules exposed to VO. The results were further verified by qRT-PCR.Conclusions: In conclusion, the first neonatal RA VO mouse model was developed; furthermore, using this neonatal RA VO mouse model, we revealed that VO impeded RA sarcomere and T-tubule maturation, which may be the underlying causes of atrial arrhythmias in adult patients with ASD.
Enhancing English reading skills and self-regulated learning through online collaborative flipped classroom: a comparative study
Authors: Wang Ying 
Published: October 2023

IntroductionThis research investigates the effectiveness of an online collaborative flipped classroom approach in enhancing English reading skills and self-regulated learning among Chinese English learners.MethodsA total of 71 participants were divided into three instructional groups: traditional instruction (TI) group (n = 24), flipped instruction (FI) group (n = 22), and online flipped instruction (OFI) group (n = 25). The participants’ reading comprehension ability was assessed using the reading section of the IELTS exam. Self-Regulated Learning (SRL) strategy use was evaluated using a questionnaire, and weekly online quizzes assessed participants’ understanding of course materials. Online learning behaviors were examined by considering online log-on times. The instruction period lasted for 12 weeks, with pre-tests and post-tests conducted to measure progress.ResultsThe results indicated that both the FI and OFI groups outperformed the TI group in terms of reading comprehension and self-regulated learning. Furthermore, the OFI students demonstrated superior online learning behaviors and objective performances compared to the FI students.DiscussionThese findings suggest that the integration of flipped and online instruction methods holds promise for improving English reading skills and enhancing self-regulated learning among Chinese English learners.
Impact of personality on cadet academic and military performance within mediating role of self-efficacy
Authors: Bekesiene Svajone 
Published: October 2023

BackgroundThe current operational military environment is changing, complex, unpredictable, and ambiguous. Due to such situations, soldiers are constantly forced to think about their values, norms, and roles that should be part of their profession. Consequently, they must first be educated and trained on how to behave in a particular operational military environment. Pursuing an officer’s education at military academies is very difficult not only physically but also psychologically. Cadets are required to be prepared to lead in extreme environments upon graduation. Despite the fact that military tasks are technically complex, the individual operational activities of soldiers are gaining more and more strategic meaning. Therefore, the importance of selecting the process and military education programs of soldiers is increasingly stressed. Cognitive abilities and skills individually predict performance in academic and professional settings, but it is less clear how personality can influence performance. Therefore, this study focused on the explanation of the individual factors that affect the achievements of the cadets. Specifically, the objective of this study was to examine direct and mediated relationships between personality traits and the military and academic performance of cadets.MethodsThis study followed a quantitative method analysis. The research models were assessed using the structural equation modeling technique. Bootstrap was applied to evaluate a 95% level confidence interval on estimates with 5,000 bootstrap samples, and to evaluate direct and indirect effects. The analysis was based on a sample of 120 cadets from the Lithuanian Military Academy. The effects on military and academic performance were evaluated using the Self-Efficacy scale, the Big Five personality trait scale, academic performance was evaluated through academic grades and military performance was evaluated using instructor ratings.ResultsTo support our hypotheses, it was found that self-efficacy has a mediating effect on the performance of cadets. Additionally, the traits of conscientiousness, openness to experience and extraversion were related to both military and academic performance. Furthermore, self-efficacy appeared as a partial mediator of the relationship between personality traits and cadet performance.ConclusionThe findings of this study help clarify the relationship between the personality traits of the cadets and the military and academic performance. In addition, these results may be useful for the further development of military education and training, for the development of testing, and selection of military personnel.
Caffeinated energy drink consumption among Emirati adolescents is associated with a cluster of poor physical and mental health, and unhealthy dietary and lifestyle behaviors: a cross-sectional study
Authors: Faris MoezAlIslam E. , Al Gharaibeh Fakir , Islam M. Rezaul , Abdelrahim Dana , Saif Eman Rashid , Turki Eman Ali , Al-Kitbi Mahra Khalfan , Abu-Qiyas Salma , Zeb Falak , Hasan Hayder , Hashim Mona S. , Osaili Tareq M. , Radwan Hadia , Cheikh Ismail Leila , Naja Farah , Bettayeb Fatima Zohra , Obaid Reyad Shaker 
Published: October 2023

BackgroundConsumption of caffeinated energy drinks (CED) has escalated during the last few years, especially among schoolchildren, with evident adverse health sequelae in this critical age group.ObjectiveThis study examined the prevalence of CED consumption and its associations with sleep, physical and mental health, and dietary and lifestyle habits among schoolchildren in the United Arab Emirates (UAE).MethodA structured self-administered online questionnaire was developed and disseminated among schoolchildren aged 14–18 years, selected from schools of the seven emirates of the UAE.ResultsMore than 4,500 (N= 4,648) responses received. A relatively low prevalence of CED consumption (20%) was found among schoolchildren in the UAE. However, those who reported CED consumption were more likely to report unhealthy dietary (skipping breakfast, frequent snacking, and eating fast foods, low fruit, and vegetable intake) and lifestyle behaviors (long screen time, poor sleep health), in addition to poor self-reported mental and physical health than non-users. CED consumption was significantly and variably associated with multiple sociodemographic factors such as students’ nationality, parental companionship, sex, school type, education level (children’s and parents’), daily allowance, academic performance, screen time, sleep quality parameters, self-reported physical and mental health, and parents’ employment. Sources of knowledge about CED were social media (55%), friends/schoolmates (52%), and family members (52%). Students believed that CED constitute sugar (87%), caffeine (69%), artificial flavors (67%) sweeteners (54%), and stimulating components (43%). The majority (70%) of students reported that CED consumption increases the risks for heart disease, diabetes, high blood sugar (65%), addiction (64%), high blood pressure (59%), and obesity (57%).ConclusionThese results offer important insights for health professionals, child health specialists, policymakers, and parents in the UAE regarding adolescents’ attitudes, knowledge and behaviors toward CED consumption.
Post-marketing safety surveillance for both CRM197 and TT carrier proteins PCV13 in Jiangsu, China
Authors: Hu Ran , Liu Yuanbao , Zhang Lei , Kang Guodong , Xu Borong , Li Mingma , Yu Jing , Zhu Yuanyuan , Guo Hongxiong , Wang Zhiguo 
Published: October 2023

BackgroundThis study is to evaluate the safety of two kinds of PCV13 carriers by monitoring the occurrence of adverse event following immunization (AEFI) after the launch of two kinds of PCV13 carriers in Jiangsu Province, China.MethodsThe AEFI Information System (CNAEFIS) of mainland China was used to monitor the incidence and classification of adverse reactions of the CRM197-carrier protein PCV13 and TT-carrier protein PCV13 vaccines.ResultsThere was no statistical difference between the cumulative reported incidence of AEFI between the two vaccines from 2020 to 2022 (χ2 = 1.991, p &lt; 0.158). 96.62% of the AEFIs were classified as common reactions; rare reactions and coincidental events only accounted for 2.99 and 0.39% of all the AEFI cases, respectively. Redness (2.6 cm–5 cm) is the commonest symptom at the injection site for both vaccines. More than 97% of AEFIs occurred between 30 min and 3 days after administration for both types of PCV13.ConclusionBoth vaccines perform well in terms of safety. We did not identify any new/unexpected safety concern from the NAEFISS during a 4 years timespan.
Labeled as “drug-seeking”: nurses use harm reduction philosophy to reflect on mending mutual distrust between healthcare workers and people who use drugs
Authors: Febres-Cordero Sarah , Shasanmi-Ellis Rebecca O. , Sherman Athena D. F. 
Published: October 2023

IntroductionOver 50 years of approaching drug use from the “War on Drugs” has led to ignoring the systemic structural and social determinants of health, enforced drug use stigma, and damaging stereotypes of people who use drugs or are labeled as “drug-seeking,” and sorely failed to support those needing assistance.On philosophy of harm reduction and powerPeople who use drugs are often disenfranchised and pathologized by being labeled as “a drug addict,” which then serves as a rationalization for mistreatment by healthcare providers. This is in opposition to a harm-reduction approach. Harm reduction philosophy is an epistemic valuation necessary for drug use stigma and our moral obligation to reduce harm from interlocking systems of power that perpetuate harm.On drug-seeking, mistrust, and human rightsWe have encountered many clients who use drugs that report harmful interactions with healthcare providers. Harm reduction is an issue of health equity, social justice, and fundamental human rights. This paper presents three vignettes, the author’s experiences of being labeled as—and advocating for family members labeled as “drug-seeking.”DiscussionTo better serve as healthcare providers, workers must be equipped to work with people who use drugs and reinforce the social justice commitment against medical stigma, neglect, racism, and inadequate pain coverage and withdrawal treatment. Nurses and our epistemic lens can meet the challenge of complex intersectional issues affecting our use of power to develop more just and equitable health systems and advance our rebuilding of a trusting relationship with the people we serve.
Three Decades Single Center Experience of Airway Complications After Lung Transplantation
Authors: van Pel R. , Gan C. T. , van der Bij W. , Verschuuren E. A. M. , van Gemert J. P. A. , Van De Wauwer C. , Erasmus M. E. , Slebos D. J. 
Published: October 2023

Post lung transplantation airway complications like necrosis, stenosis, malacia and dehiscence cause significant morbidity, and are most likely caused by post-operative hypo perfusion of the anastomosis. Treatment can be challenging, and airway stent placement can be necessary in severe cases. Risk factors for development of airway complications vary between studies. In this single center retrospective cohort study, all lung transplant recipients between November 1990 and September 2020 were analyzed and clinically relevant airway complications of the anastomosis or distal airways were identified and scored according to the ISHLT grading system. We studied potential risk factors for development of airway complications and evaluated the impact on survival. The treatment modalities were described. In 651 patients with 1,191 airway anastomoses, 63 patients developed 76 clinically relevant airway complications of the airway anastomoses or distal airways leading to an incidence of 6.4% of all anastomoses, mainly consisting of airway stenosis (67%). Development of airway complications significantly affects median survival in post lung transplant patients compared to patients without airway complication (101 months versus 136 months, p = 0.044). No significant risk factors for development of airway complication could be identified. Previously described risk factors could not be confirmed. Airway stents were required in 55% of the affected patients. Median survival is impaired by airway complications after lung transplantation. In our cohort, no significant risk factors for the development of airway complications could be identified.
December 2022-Printed Issue
Authors:   Patient Safety Authority
Published: October 2023

The December 2022 issue of Patient Safety is available to read and download at no charge. Our latest publication offers vital information, tools, resources, and articles that can help improve the safety and well-being of patients and healthcare workers in the new year. • Taylor et al. describea patient safety initiative that reduced the incidence of perioperative emergence delirium at a Veterans Affairs hospital (https://patientsafetyj.com/index.php/patientsaf/article/view/emergence-delirium)—and provide you with everything you need to replicate their work. • What is the past, present, and future of nursing? Nursing professor Eileen Fruchtl discusses how nursing education has been evolving and what it may become (https://patientsafetyj.com/index.php/patientsaf/article/view/nursing-education) following the pandemic, and Toothaker et al. look at the challenges recently graduated nurses face as they transition into the workforce (https://patientsafetyj.com/index.php/patientsaf/article/view/nurse-transition). • John Olsen et al. describe the success and impact of Jefferson Health’s peer support program, RISE (https://patientsafetyj.com/index.php/patientsaf/article/view/Jefferson-rise) (Resilience in Stressful Events). • Abigail Baluyot et al. share communication problems they identified in patient hand-offs between hospitals and skilled nursing facilities (https://patientsafetyj.com/index.php/patientsaf/article/view/hospital-snf-communication), and what they did to improve the process. This issue also includes an important safety alert about the risk of air embolism during cardiac ablation procedures (https://patientsafetyj.com/index.php/patientsaf/article/view/air-embolism), an update to acute care reporting rates in Pennsylvania last year (https://patientsafetyj.com/index.php/patientsaf/article/view/2021-data-update), and an inside look at how prison systems in Pennsylvania deliver healthcare to inmates. Patient Safety is fully open access (no fees for authors or readers). We welcome submissions from all over the world. If your work can help advance patient safety, please submit it to us for consideration (https://patientsafetyj.com/for-authors), and kindly share our journal with friends, family, colleagues, and caregivers.