bluuebunny/crossref_metadata_2025_split huggingface dataset:
Barriers to using physical exercise as an intervention within inpatient mental health settings: A systematic review
Authors: McKenna Catriona , Moyo Beata , Goodwin John 
Published: February 2024

AbstractService providers find it difficult to implement Physical Exercise (PE) strategies in routine care within inpatient mental health settings even though they perceive it to be an effective therapy, with a robust evidence base. Identifying barriers that exist can assist with the development of future interventions and support PE services being introduced into mental health inpatient settings. The aim of this systematic review was to synthesise the evidence on the barriers or perceived barriers that exist amongst service users and providers when incorporating PE as an intervention within inpatient mental health settings. Using a narrative synthesis approach, four main themes were identified: (i) Barriers relating to service users' mental and physical health, (ii) Factors relating to service providers, (iii) Environmental factors and (iv) Cultural factors. Both service users and providers need more knowledge on implementing PE in inpatient mental health settings. Tailored programmes for service users are warranted, with specialist roles for staff developed.
Comparative effectiveness of pericapsular nerve group block versus fascia iliac compartment block on postoperative wound pain management in patients undergoing hip fracture surgery: A systematic review and meta‐analysis
Authors: Mou Zhefei , Xiang Lingping , Ni Yueping 
Published: February 2024

AbstractHip fracture surgeries are challenging, with postoperative pain management being a critical component of patient care. This systematic review and meta‐analysis aimed to compare the effectiveness of Pericapsular nerve group block (PENGB) and fascia iliac compartment block (FICB) in postoperative wound pain management for patients undergoing hip fracture surgery. The study followed the PRISMA guidelines and was structured around the PICO framework. Comprehensive searches were conducted across PubMed, Embase, Web of Science, and the Cochrane Library. Inclusion criteria were limited to RCTs comparing the effectiveness of PENGB and FICB in adult patients undergoing hip fracture surgery. Key outcomes included pain control effectiveness, safety, and complication incidence. The quality of studies was assessed using the Cochrane Collaboration's risk of bias tool. Statistical heterogeneity was evaluated using I2 statistics, and meta‐analysis effect values were calculated using random‐effects or fixed‐effect models, depending on the degree of heterogeneity. The search identified 1095 articles, with 5 studies meeting inclusion criteria. The meta‐analysis revealed that PENGB and FICB were comparable in managing postoperative pain and opioid consumption. However, PENGB significantly reduced the incidence of quadriceps muscle weakness (RR = 0.12, p < 0.05) and did not increase the risk of PONV (RR = 1.36, p = 0.51), suggesting its advantage in maintaining motor function without adding to PONV complications. No significant publication bias was detected. PENGB is comparable to FICB in pain and opioid consumption management after hip fracture surgeries. Its significant benefit lies in reducing the incidence of quadriceps muscle weakness, facilitating better postoperative mobility. Additionally, PENGB does not increase the risk of postoperative nausea and vomiting, underlining its suitability for comprehensive postoperative care in hip fracture patients.
Anemoside B4 alleviates arthritis pain via suppressing ferroptosis‐mediated inflammation
Authors: Guo Chenlu , Yue Yuanfen , Wang Bojun , Chen Shaohui , Li Dai , Zhen Fangshou , Liu Ling , Zhu Haili , Xie Min 
Published: February 2024

AbstractChronic pain is the key manifestations of rheumatoid arthritis. Neuroinflammation in the spinal cord drives central sensitization and chronic pain. Ferroptosis has potentially important roles in the occurrence of neuroinflammation and chronic pain. In the current study, mouse model of collagen‐induced arthritis was established by intradermal injection of type II collagen in complete Freund's adjuvant (CFA) solution. CFA inducement resulted in swollen paw and ankle, mechanical and spontaneous pain, and impaired motor coordination. The spinal inflammation was triggered, astrocytes were activated, and increased NLRP3‐mediated inflammatory signal was found in CFA spinal cord. Oxidative stress and ferroptosis in the spinal cord were manifested. Meanwhile, enhancive spinal GSK‐3β activity and abnormal phosphorylated Drp1 were observed. To investigate the potential therapeutic options for arthritic pain, mice were intraperitoneally injected with AB4 for three consecutive days. AB4 treatment reduced pain sensitivity and increased the motor coordination. In the spinal cord, AB4 treatment inhibited NLRP3 inflammasome‐mediated inflammatory response, increased antioxidation, decreased mitochondrial reactive oxygen species and ferroptosis. Furthermore, AB4 decreased GSK‐3β activity by binding with GSK‐3β through five electrovalent bonds. Our findings indicated that AB treatment relieves arthritis pain by inhibiting GSK‐3β activation, increasing antioxidant capability, reducing Drp1‐mediated mitochondrial dysfunction and suppressing neuroinflammation.
Immediately versus early placed bone‐level‐tapered implants supporting all‐ceramic crowns on titanium base abutments: 1‐year radiographic and pink esthetic outcomes of a multicenter pilot RCT
Authors: Hicklin Stefan P. , Sailer Irena , Todorovic Ana , Mojon Philippe , Worni Andreas , Strasding Malin 
Published: February 2024

AbstractObjectivesAim of this study was to assess survival rates, radiographic, and pink esthetic outcomes of a bone‐level‐tapered (BLT) implant following immediate or early implant placement.Materials and MethodsPatients in need of tooth extraction and one implant in the anterior or premolar area were recruited in five centers. Patients were randomly assigned to the immediate or early placement protocol. Implants were restored with all‐ceramic crowns cemented to titanium‐base‐abutments. Radiographic bone levels, implant stability quotient (ISQ), and pink esthetic outcomes were assessed.Data were analyzed descriptively. Level of significance was set at 0.05. Differences between groups were tested using Wilcoxon‐signed‐rank and Mann–Whitney‐U test as nonparametric tests.ResultsA total of 60 patients received 60 BLT implants (Institut Straumann). At 12‐months, 59 implants (98.3%) were osseointegrated. The mean distance from implant shoulder to first bone‐to‐implant contact was 0.15 ± 0.59 mm without significant differences between the groups. Median ISQ values increased from 75.5 to 78.5. A mean buccal recession of 0.1 ± 0.70 mm occurred with no difference between groups. The mean papilla height gain in both groups was 0.5 ± 1.47 mm mesially and 0.4 ± 1.36 mm distally.ConclusionsAfter 1 year, immediately and early placed BLT implants exhibit similar bone level changes, ISQ values, and pink esthetic outcomes.Clinical SignificanceThe present research contributes to the knowledge on clinical outcomes of immediately and early placed BLT implants restored with buccally microveneered ceramic single crowns out of two different ceramic materials. The research shows that similar esthetic and radiographic outcomes can be reached by means of immediate implant placement compared to the conventional early placement protocol. The improvement of esthetic soft‐tissue parameters over time was shown for both implant placement protocols.
Social Entrepreneurs as Ecosystem Catalysts: The Dynamics of Forming and Withdrawing from a Self‐Sustaining Ecosystem
Authors: Savaget Paulo , Ozcan Pinar , Pitsis Tyrone 
Published: February 2024

AbstractCreating a long‐lasting impact is one of the defining goals of social entrepreneurship. Yet, social entrepreneurs often face a dilemma between sustaining their organization and offering a permanent fix to a social problem. We question the assumption that organizational permanence and growth are intrinsically desirable for social entrepreneurs and propose an alternative, an inductively grounded model of ecosystem leadership, which we term ecosystem catalysis. Through a single case study of social entrepreneurs addressing the lack of access to diarrhoea treatment in Zambia, we conceptualize ecosystem catalysis as a process through which an organization forms an ecosystem around a new value proposition while gradually making itself redundant, ultimately withdrawing from the ecosystem without compromising its functioning. Our work contributes to ecosystem literature by contrasting the key aims and mechanisms of an ecosystem catalyst to those of an orchestrator and identifying the conditions under which catalysing may be a better choice than orchestrating an ecosystem. We contribute to social entrepreneurship literature by decoupling social impact from organizational growth and permanence and presenting a more dynamic model of social impact resulting from distributed contributions in ecosystems.
Congregation Over Denomination: Analyzing Psychological Reactions to a Church Ruling on Same Sex Marriage
Authors: Wilkins Clara L. , Lisnek Jaclyn A. , Saadatian Kimia , Martin Lerone A. 
Published: February 2024

AbstractIn 2019, the United Methodist Church (UMC) voted to maintain their stance of prohibiting the ordination of gay clergy and the performance of same‐sex marriages within the church. As part of a multi‐method study, we hosted focus groups, interviews, and conducted surveys with 54 individuals from four UMC churches to assess attitudes about the outcome of the vote. Consistent with hypotheses, the majority expressed disappointment and evidence of having resolved cognitive dissonance that arose from continued church attendance. Both quantitative and qualitative measures indicated a tendency for participants to disidentify with the global church and denomination but to strengthen their commitment and ties to their more LGBTQ‐friendly local congregations. We identified themes of resilience, community, and increased activism. We discuss implications for other organizations grappling with the inclusion of sexual and gender minorities as well as implications for political polarization more broadly.
Retrospective evaluation of 22 dogs with leptospirosis treated with extracorporeal renal replacement therapies (2018‐2021)
Authors: Ioannou Antonia Da Fonseca , Tai Carolyn , Labato Mary Anna , Butty Emmanuelle M. 
Published: February 2024

AbstractBackgroundOutcomes of dogs with acute kidney injury secondary to leptospirosis (AKI‐L) treated using renal replacement therapies (RRT) are poorly characterized.Hypothesis/ObjectivesDescribe survival to discharge, short (≤30 days) and long‐term (≥6 months) outcomes of AKI‐L dogs receiving RRT and determine if there is a significant difference in maximum blood urea nitrogen (maxBUN), maximum creatinine (maxCr), maximum bilirubin (maxBili) and the number of body systems affected between survivors and non‐survivors.AnimalsTwenty‐two client‐owned dogs with AKI‐L receiving RRT.MethodsRetrospective medical record review of dogs with AKI‐L that received RRT between 2018 and 2021.ResultsSixteen of 22 (73%) dogs survived to discharge. Of the survivors, 13 (81%) were alive >30 days from discharge and 12 (75%) were alive at 6 months from discharge. Factors significantly higher in non‐survivors included number of body systems affected (survivors: 1 (19%), 2 (50%), 3 (25%) and 4 (6%) vs non‐survivors: 3 (33.3%), and 4 (66.7%); P = .01) and median maxBili (survivors: 1.9 mg/dL; range, 0.1‐41.6 vs non‐survivors: 21.0 mg/dL; range, 12.3‐38.9; P = .02). There was no significant difference in median maxBUN (survivors: 153.0 mg/dL; range, 67‐257 vs non‐survivors: 185.5 mg/dL; range, 102‐218; P = .44) and median maxCr (survivors: 9.8 mg/dL; range, 6.2‐15.9 vs non‐survivors: 9.8 mg/dL; range, 8.4‐13.5; P = .69) between survivors and non‐survivors.Conclusions and Clinical ImportanceRegardless of azotemia severity, dogs with AKI‐L receiving RRT have a good survival rate to discharge. The number of body systems affected and hyperbilirubinemia might be associated with worse outcomes.
Juvenile production technology for tiger shrimp, Penaeus monodon, through different stocking density using a recirculation system
Authors: Pantjara Brata , Novriadi Romi , Hendrajat Erfan A. , Herlinah Herlinah , Reynalta Ricko , Prihadi Tri H. , Kristanto Anang H. , Syah Rachman , Subagja Jojo , Widyastuti Yohanna R. , Saputra Adang , Radona Deni , Taukhid Imam 
Published: February 2024

AbstractAquaculture recirculation technology has evolved in recent years, as it can save water use and maintain good water quality during tiger shrimp fry rearing and ultimately increase juvenile production. The recirculation technology in this experiment is expected to be adopted by small‐scale tiger shrimp seed farmers. This study aims to develop the technology for producing a juvenile tiger shrimp recirculation system to support shrimp cultivation in ponds. The recirculation system container comprises a biofiltration tank filled with oysters, seaweed, and tilapia. Containers to keep tiger shrimp larvae alive in the recirculation system use a round‐shaped container with a volume of 2 m3. Tiger shrimp larvae were cared for at; A. density of 2000 individuals/m2; B. density of 1500 individuals/m2; and C. density of 1000 individuals/m2. This study found that the survival rate of tiger shrimp in treatments C and B were high, reaching 96.800b ± 2.716% and 91.62b ± 3.432%, respectively, while survival in treatment A was the lowest, at 81.700a ± 4.715%.
Exploration of cell type–specific somatic mutations in schizophrenia and the impact of maternal immune activation on the somatic mutation profile in the brain
Authors: Du Jianbin , Nakachi Yutaka , Murata Yui , Kiyota Emi , Kato Tadafumi , Bundo Miki , Iwamoto Kazuya 
Published: February 2024

AimSchizophrenia (SZ) is a severe psychiatric disorder caused by the interaction of genetic and environmental factors. Although somatic mutations that occur in the brain after fertilization may play an important role in the cause of SZ, their frequencies and patterns in the brains of patients and related animal models have not been well studied. This study aimed to find somatic mutations related to the pathophysiology of SZ.MethodsWe performed whole‐exome sequencing (WES) of neuronal and nonneuronal nuclei isolated from the postmortem prefrontal cortex of patients with SZ (n = 10) and controls (n = 10). After detecting somatic mutations, we explored the similarities and differences in shared common mutations between two cell types and cell type–specific mutations. We also performed WES of prefrontal cortex samples from an animal model of SZ based on maternal immune activation (MIA) and explored the possible impact of MIA on the patterns of somatic mutations.ResultsWe did not find quantitative differences in somatic mutations but found higher variant allele fractions of neuron‐specific mutations in patients with SZ. In the mouse model, we found a larger variation in the number of somatic mutations in the offspring of MIA mice, with the occurrence of somatic mutations in neurodevelopment‐related genes.ConclusionSomatic mutations occurring at an earlier stage of brain cell differentiation toward neurons may be important for the cause of SZ. MIA may affect somatic mutation profiles in the brain.
Mathematical structuralism and bundle theory
Authors: Assadian Bahram 
Published: February 2024

AbstractAccording to the realist rendering of mathematical structuralism, mathematical structures are ontologically prior to individual mathematical objects such as numbers and sets. Mathematical objects are merely positions in structures: their nature entirely consists in having the properties arising from the structure to which they belong. In this paper, I offer a bundle‐theoretic account of this structuralist conception of mathematical objects: what we normally describe as an individual mathematical object is the mereological bundle of its structural properties. An emerging picture is a version of mereological essentialism: the structural properties of a mathematical object, as a bundle, are the mereological parts of the bundle, which are possessed by it essentially.
Consensus guidelines for nomenclature of companion animal inherited retinal disorders
Authors: Mowat Freya M. , Iwabe Simone , Aguirre Gustavo D. , Petersen‐Jones Simon M. 
Published: February 2024

AbstractCompanion animals, namely dogs, cats, and horses, can be affected with many forms of hereditary retinal disease. The number of such diseases characterized in the last decade has increased substantially, and nomenclature is nonstandardized, heterogenous, and confusing. We provide in this viewpoint article consensus guidelines for naming of companion animal hereditary retinal diseases, either prospectively or retrospectively. These consensus guidelines have been developed with the purpose of standardizing nomenclature. We provide examples for the iterative nomenclature process and a comprehensive File S1 on proposed renaming of previously described diseases.
Forecasting seasonal influenza activity in Canada—Comparing seasonal Auto‐Regressive integrated moving average and artificial neural network approaches for public health preparedness
Authors: Orang Armin , Berke Olaf , Poljak Zvonimir , Greer Amy L. , Rees Erin E. , Ng Victoria 
Published: February 2024

AbstractIntroductionPublic health preparedness is based on timely and accurate information. Time series forecasting using disease surveillance data is an important aspect of preparedness. This study compared two approaches of time series forecasting: seasonal auto‐regressive integrated moving average (SARIMA) modelling and the artificial neural network (ANN) algorithm. The goal was to model weekly seasonal influenza activity in Canada using SARIMA and compares its predictive accuracy, based on root mean square prediction error (RMSE) and mean absolute prediction error (MAE), to that of an ANN.MethodsAn initial SARIMA model was fit using automated model selection by minimizing the Akaike information criterion (AIC). Further inspection of the autocorrelation function and partial autocorrelation function led to ‘manual’ model improvements. ANNs were trained iteratively, using an automated process to minimize the RMSE and MAE.ResultsA total of 378, 462 cases of influenza was reported in Canada from the 2010–2011 influenza season to the end of the 2019–2020 influenza season, with an average yearly incidence risk of 20.02 per 100,000 population. Automated SARIMA modelling was the better method in terms of forecasting accuracy (per RMSE and MAE). However, the ANN correctly predicted the peak week of disease incidence while the other models did not.ConclusionBoth the ANN and SARIMA models have shown to be capable tools in forecasting seasonal influenza activity in Canada. It was shown that applying both in tandem is beneficial, SARIMA better forecasted overall incidence while ANN correctly predicted the peak week.
Forward Kinematics Analysis of High-Precision Optoelectronic Packaging Platform
Authors: Wang Ziyang , Zhou Haibo , Xiao Linjiao , Duan Lian 
Published: February 2024

Abstract
To meet the requirements of high-precision motion control for optoelectronic packaging platforms, we propose an improved particle swarm optimization (PSO) and backpropagation (IPSO-BP) neural network for solving the forward kinematics problem (FKP) of platforms. The focus of this paper is the 6-pss flexible parallel platform commonly used in optoelectronic packaging. First, a platform inverse kinematics problem (IKP) based on a flexibility matrix is solved using geometric and vector analysis. The conventional PSO-BP network is then optimized utilizing uniform design (UD), a random learning strategy, and space reduction techniques in FKP. Finally, simulations and experiments demonstrate that the proposed IPSO-BP network for solving the FKP on high-precision optoelectronic packaging platforms is feasible. Compared to BP and PSO-BP, this network has a higher resolution, faster convergence speed, and error control at the submicron level, which satisfies the motion control requirements of the platform at the micron level. This study lays a solid foundation for the production of high-quality devices in optoelectronic packaging.
Heat Transfer and Flow Characteristics of Channel Impingement Cooling Structure at Leading Edge Inside Turbine Blades Using Large Eddy Simulation
Authors: Wang Huihui , Deng Qinghua , Feng Zhenping 
Published: February 2024

Abstract
As a main part of multichannel wall jet cooling structure, channel impingement cooling is a cooling strategy of great concern at the leading edge inside of the turbine blade. In this paper, heat transfer and flow behavior in the channel impingement cooling structure are investigated by large eddy simulation (LES). The results imply that impingement created by curvature-induced centrifugal instabilities in the turning region of the cooling channel is dominated by a streamwise vortex system containing a counter-rotating Dean vortex, which presents high heat transfer streaks along the streamwise direction on the target wall. The intensely unsteady nature of the cooling jet induced by a lack of equilibrium between the pressure gradient and the centrifugal force is precisely captured herein by LES. An attaching-wall jet formed on the outer wall downstream of the cooling channel has highly three-dimensional characteristics not observed by Reynolds-averaged Navier–Stokes equations (RANS). Heat transfer augmentation on the target wall of the cooling channel is mainly due to the intensifying streamwise vortex system developing in the turning region as driven by the centrifugal force. This research work will provide a reference for the optimization and application of multichannel wall jet cooling for gas turbine blades.
Integrated Wheel–Foot–Arm Design of a Mobile Platform With Linkage Mechanisms
Authors: Du Yuting , Ruan Qiang , Yao Yan-an 
Published: February 2024

Abstract
Inspired by lizards, a novel mobile platform with revolving linkage legs is proposed. The platform consists of four six-bar bipedal modules, and it is designed for heavy transportation on unstructured terrain. The platform possesses smooth-wheeled locomotion and obstacle-adaptive legged locomotion to enhance maneuverability. The kinematics of the six-bar bipedal modules is analyzed using the vector loop method, subsequently ascertaining the drive scheme. The foot trajectory compensation curve is generated using the fixed-axis rotation contour algorithm, which effectively reduces the centroid fluctuation and enables seamless switching between wheels and legs. When encountering obstacles, the revolving linkage legs act as climbing arms, facilitating seamless integration of wheel, foot, and arm. A physical prototype is developed to test the platform on three typical terrains: flat terrain, slope, and vertical obstacle. The experimental results demonstrated the feasibility of the platform structure. The platform can climb obstacles higher than its own height without adding extra actuation.