bluuebunny/crossref_metadata_2025_split huggingface dataset:
The Relapse of Epithelial Ovarian Cancer Under 2-Year Post-Treatment Observation Based on VEGF-A and VEGFR-2 Expression
Authors: Dwipoyono Bambang , Adisasmita Asri C , Choirunisa Septyana 
Published: December 2023

Background: Epithelial ovarian cancer is one of the most formidable lethal malignancies, with a 5-year survival rate of approximately 35% for advanced-stage ovarian carcinoma and a 10-year follow-up rate of about 18%. Although several regimens have been evaluated for improvement, relapse remains an inevitable challenge. Recently, specific prognostic factors related to “cell behavior”, including cell proliferation activity such as angiogenesis VEGF (vascular endothelial growth factors) have been recognized. Therefore, this study aims to predict relapse of epithelial ovarian cancer within two years of follow-up based on the expression of vascular endothelial growth factor A (VEGF-A) and vascular endothelial growth factor receptor-2 (VEGFR-2) at the mRNA and protein levels. Methods: This study was conducted at “Dharmais” Cancer Hospital (DCH) with a retrospective cohort design in patients with advanced epithelial ovarian cancer who received complete treatment. The role of angiogenesis factors on relapse in epithelial ovarian cancer in 2 years of observation was evaluated. Semiquantitative expression analysis of VEGF-A and VEGFR-2 (protein) was conducted through the immunohistochemical method using the avidin-biotinperoxidase complex (ABC) method. Meanwhile, the semiquantitative expression of VEGF-A and VEGF-R2 (mRNA level) was carried out using RT-PCR (Reverse Transcription- Polymerase Chain Reaction) - Zyber Green Bioline Kit - method, with specific primers. Results: From 2008 to 2012, only 20 patients were tested for the role of VEGF-A and VEGFR-2 on the incidence of relapse within two years of observation. Among the 20 patients examined for VEGF-A and VEGFR-2 expression, 50% remained disease-free for 20 months, resulting in a cumulative disease-free survival probability of 48.1% for the patient. Those with positive VEGF-A expression at the mRNA level had a shorter median disease-free survival time (18 months), with a lower disease-free survival probability. Patients who showed positive VEGFR-2 expression (at the protein level) had a shorter median disease-free survival time, a lower cumulative probability of disease-free survival (DFS), and a greater risk of relapse (3 times) than patients who did not express (negative) VEGFR-2. In addition, the ROC-based analysis was also performed. Conclusions: Expression of both VEGF-A and VEGFR-2 at mRNA and protein levels can be used as a predictor for relapse of epithelial ovarian cancer. This study showed that a positive VEGF-A expression at the mRNA level is associated with a twofold higher risk of relapse, while positive VEGF-R2 expression at the protein level is associated with a threefold shorter risk of relapse than negative expression.
A Case Series of Rare Vaginal Malignant Melanoma
Authors: Soemanadi Soemanadi , Hanafi Widyorini Lestari Hutami , Madjid Veinardi 
Published: December 2023

Introduction: Vaginal melanoma is a rare malignancy. Sadly, melanoma is a very aggressive tumor with a 5-year survival rate of 5%–25%. There is no publication about the incidence of vaginal malignant melanoma in Indonesia. Due to the lack of cases in Indonesia, this study aims to report the challenges and explore the risk factor, treatment, and prognosis of Vaginal Malignant Melanoma. Case Presentation: This case series report 2 patient with vaginal malignant melanoma who were diagnosed at Dharmais Cancer Center Hospital. Conclusions: Diagnosis and optimal treatment plans can be established through rapid and precise recognition of Malignant Melanoma to achieve better outcomes.
Myocardial Infiltration in Primary Mediastinal B-Cell Lymphoma Detected by Cardiac Magnetic Resonance Imaging
Authors: Sutedjo Verawati , Soewondo Widiastuti , Yuniarti Mira , Tenggara Jeffry Beta , Erawati Dini Rachma 
Published: December 2023

Introduction: Cardiac involvement, particularly myocardial infiltration in primary mediastinal lymphoma, is a rare occurrence with an incidence of only 9% in known cases of primary malignancy. Neoplasm infiltration into the myocardium manifests through direct invasion, hematogenous spread, transvenous invasion through the great veins, or lymphangitic spreading in the mediastinal. Myocardial infiltration in lymphoma presents a grim prognosis and its treatment may be associated with specific risks, such as myocardial rupture. Various imaging modalities may detect cardiac involvement, with cardiac magnetic resonance (CMR) imaging considered the gold standard. CMR enables clear delineation of myocardial infiltration, making it valuable for local staging, pretreatment planning, and evaluating treatment response. Case Presentation: : A 37-year-old woman patient was diagnosed with primary mediastinal large B-cell lymphoma. Mild chest discomfort and shortness of breath were observed 3 months before hospital admission. A thorax CT scan showed a heterogeneous contrast-enhancing mass with a central necrotic area in the anterior mediastinum. Following thoracotomy and tumor debulking, the patient complained of severe crushing chest pain radiating to her back, accompanied by new T wave inversion on ECG and elevated cardiac troponin levels a week after surgery. Coronary angiogram results showed a normal coronary artery. Subsequent cardiac MRI showed tumor infiltration into the anterior pericardial space, as well as the myocardium of the left and right ventricles. Chemotherapy was promptly initiated, resulting in a gradual improvement of symptoms. Conclusions: In this study, we discuss the use of 3D-CRT in the re-irradiation of NPC with its limitation on obtaining optimum dose sculpture compared to more sophisticated and widely spread modalities like IMRT. However, with careful planning, we can still obtain optimum tumor dose, minimize OAR dose, and subsequently late toxicities that come after. We hope that this study can bring hope to centers with limited facilities, and we suggest further studies on reirradiation, especially in OAR dose tolerance guidelines.
Cancellation of 2020 Conference: The Canadian Association of Action Research in Education
Authors: Barker Marianne 
Published: December 2023

After a very tumultuous spring, the executive of CAARE’s parent organization - the Canadian Society for the Study of Education (CSSE) - decided to cancel its upcoming conference in London, Ontario this June. CAARE has, of course, decided to follow suit. This was a lamentable decision but one that helped to insure public health.
While presenters will not get a chance to discuss their research at the 2020 conference, we are happy to announce that we will still go through with the publication of the association’s conference proceedings, which will be found on the CJAR website in the coming months.
In the long term, we hope to see all members of CAARE at the 2021 conference which will be held at the University of Alberta in Edmonton.
Action Research Network of the Americas Annual Conference, June 28-30, 2022, Southern Utah University, Cedar City, Utah, USA
Authors: Clausen Kurt W. 
Published: December 2023

The ARNA conference will be meeting in Cedar City, Utah at Southern Utah University between San Diego, CA between June 28 and 30, 2022.
Link to information: https://arnawebsite.org/conferences/southern-utah-university/
Upcoming Events at Community-Based Research Canada until the end of May 2022
Authors: Canadian Journal of Action Research  
Published: December 2023

Community-Based Research Canada offers ongoing events including the upcoming webinar “Making Waves in Equity, Diversity and Inclusion” on February 23, 1pm, the webinar “Omamoo Wango Gamik: Creating a home for Indigenous youth during a global pandemic” on May 17, 12-1pm with an accompanying live discussion on March 24, 12-1:15pm. Finally, SFU’s Community-Engaged Research Initiative Conference will be held between May 26, 7pm to May 29, 11 pm.
Link to information: https://www.communityresearchcanada.ca/events
An Action Research Study of Using Group-Based Remote Learning with ESL High School Students in English Language Arts
Authors: Buelvas Danielle 
Published: December 2023

At the time of writing, New York City high schools had been working remotely for a year, with educators facing some great challenges. Working remotely marked a significant difference in the way we teach and the way our students learn. Classroom spaces were no longer room numbers on doors; they were virtual meeting room numbers on platforms like Teams or Google Classroom, and they were accessible from anywhere by Wi-Fi. According to the United Nations Educational, Scientific, and Cultural Organization (UNESCO, 2020), school closures caused by the Covid-19 pandemic affected over 1.5 billion students and families. The Covid-19 pandemic presented multiple challenges for teaching students with English as a second language in an online instructional environment, but also opportunities for collaboration, training, and communication for inclusive educators to strive to meet the needs of their students. This article addresses the following teacher-researcher questions: 1) What opportunities do I find most rewarding teaching in an online environment to students for whom English is a second language? 2) What do I find to be most challenging teaching English second language (ESL) students in the online context? 3) How can media play a part in online teaching and learning, and how do students respond to online learning with these mixed media platforms? 4) What recommendations can be offered to other inclusive educators who are teaching online? The researcher discusses the methodological approach used to conduct the research, using methods including surveys and field notes. Further research conducted was based on the researcher’s journal of field notes kept throughout teaching a unit titled “Beowulf.” An analysis of student assessment data is also provided to show progress, where applicable, for one class of English Second Language students.
Eﬀects of Balance and Proprioceptive Exercises on the Balance of Ice Hockey Players and the Risk of Lower Limb Injuries
Authors: Karvelytė Agnė , Sipavičienė Saulė 
Published: December 2023

Background. Most ice hockey injuries are contact, but about 15% are non-contact musculoskeletal injuries and lower body injuries account for 30-45% of all injuries in ice hockey players. It is believed that proprioception and balance training can improve neuromuscular control, improve its ability to synchronise the muscle joint to improve dynamic stability and improve human performance, so balance and proprioception are suggested exercises as a regular part of training.
The aim. To determine the eﬀects of a 6-week balance and proprioception training exercises on balance and lower extremity injury risk in ice hockey players.
Material and methods. 20 men were randomly divided into experimental and control groups. Six weeks were applied to the research group balance and proprioception exercises, twice a week for 45 minutes next to their regular training. The control group continued with regular training. Before and after the study, static balance was assessed by the ﬂamingo test, dynamic balance and lower extremity injury risk by the modified star excursion test, and injury risk assessment using the Functional Movement Assessment.
Results. In the intervention group after 6 weeks the static balance of the right and left leg improved statistically significantly (p<0,05), the dynamic balance of the right and left leg in the front, posteromedial, posterolateral directions (p<0,05), but functional movement patterns did not change statistically significantly (p>0,05). A statistically significant diﬀerence was found between the groups in the dynamic balance of the left and right leg in the front, posteromedial, and posterolateral directions (p<0,05) and the static balance of the right leg (p<0,05). The results of the intervention group were better compared to the control group.
Conclusions. After the application of balance and proprioception training exercises, the static and dynamic balance of ice hockey players improved and the risk of injury in ice hockey players decreased.
Recommendations. Balance and proprioception exercises should be included in hockey physical training to improve static and dynamic balance and reduce the risk of injury. When performing balance and proprioception exercises, we recommend incorporating a variety of specific movements that are similar to those performed by athletes during training and competition. In order to determine the cause of injuries and their risk, it is very important to carry out regular tests, store them and analyse them.
Keywords: balance, proprioception, hockey, injury risk
The Inﬂuence of Physical Activity and Chess Sports on Children’s Physical Condition and Cognitive Functions
Authors: Šilinė Ligita , Danilčikaitė Tautvydė , Žlibinaitė Laura 
Published: December 2023

Background. Children who play chess improve their academic results, cognitive and social skills, however, both cognitive and physical abilities are important for healthy development. Recent evidence suggests that physical activity has a positive impact not only on children’s physical abilities but cognitive functions as well. Yet it is not clear the eﬀect of physical activity and chess on children’s physical condition and cognitive functions.
The aim. To identify the inﬂuence of physical activity and chess sports on children’s physical condition and cognitive functions.
Methods. The study involved 30 children (8-9 years). They were equally divided into three groups: chess-playing (CHESS), physical activity and chess-playing (PA+CHESS), and physical activity (PA). The fnger reaching test was used to assess ﬂexibility, 10x5 m shuttlecock test was used to assess dexterity, handgrip strength was measured using the dynamometer, cognitive functions were evaluated using “MoCA-LT” and Bourdon-Anfmov tests.
Results. Flexibility and handgrip strength did not diﬀer signifcantly between groups (p>0.05). The dexterity in CHESS group was worse than in CHESS+PA and PA groups (p<0.05). The dexterity results of the CHESS+PA and PA groups did not diﬀer (p>0.05). The cognitive functions of the CHESS+PA group, as assessed by the MoCA test, were better than those of the PA group (p<0.05). No diﬀerence was found between other groups (p>0.05).
Conclusions. Children who play chess and participate in sport activity have better cognitive functions than children who only do sport. The worst results of dexterity test were in children who play chess only.
Keywords: physical condition, cognitive functions, chess sports, children.
Nursing Stress and Thought Control in a Multiperspectival Interpretive Phenomenological Analyses from the United Kingdom, United States and Switzerland
Authors: Ali Yumna , Kazmi Syeda Farhana 
Published: December 2023

Background. Nurses constitute a worldwide community of human resources committed to critical care. They are exposed to stress and intruding thoughts so they are at the risk of poor performance. The study aimed to ask experts about how can nurses manage stress eﬀectively in Asian developing countries.
The aim. To explore stress management skills for nurses to be applied in developing Asian countries through the personal lived experience of experts from developed countries. Multiperspectival Interpretive Phenomenological Analyses (MIPA) are performed case by case and across the participants to establish convergence and divergence.
Methods. This experiential exploratory descriptive qualitative study was carried out by conducting semi-structured interviews with experts residing, educated, and professionally practising in the United States of America, United Kingdom, and Switzerland, with a purposing sample of 11 stress experts who were subjected to interpretative phenomenological analysis (IPA). The current study uses HyperResearch software v.4.5.4 and also uses qualitative criteria (Lincoln & Guba, 1985) to increase data rigour and the Graneheim and Lundman method to analyse content (Graneheim & Lundman, 2004).
Results. The research data showed 102 codes, 4 experiential statements, and 15 personal experiential themes/subcategories. Strategies for stress management and thought control include the practiceof mindfulness and meditation through mindfulness-based stress reduction courses, mindfulnessbased cognitive therapy courses; and the conduction of mindfulness-based organisational education on a larger scale. Nurses can beneft from thought labelling, and cognitive defusion to challenge automatic thoughts. Systematically, nursing management can improve through intervision, on-the-job support, and balance of power gradient. Nurses must adopt stress relief strategies such as practicing self-compassion, yoga, the method of active noticing, rational emotive behaviour skills, afrmations, and acceptance.
Conclusion. Nurses face stress in daily life. Continuous and practical methods of stress management are important and contribute to stress reduction for them. It is essential for nurses to practice mindfulness, meditation, thought control, and stress relief processes to work optimally.
Keywords: stress management, thought control, nursing, psychology, qualitative.
Nutritional Status of Children with Beta Thalassemia Major
Authors: Joshi Dhara Bipin , Nayak Uma Siddharth 
Published: December 2023

Background. Children with beta thalassemia major are at risk for poor nutritional status, which can lead to signifcant health problems. It is essential to evaluate the level of malnutrition among individuals.
The aim. To assess the nutritional status of children with beta thalassemia major using body mass index.
Methods. This cross-sectional study was conducted at the District Branch of the Indian Red Cross Society in Ahmedabad, Gujarat. The purposive sampling technique was used to select 119 children with beta thalassemia major as participants. The nutritional status of children aged 8 to 18 years was assessed from September 2021 to December 2021.
Results. Out of the 119 participants, 56 (47%) were female and 63 (53%) were male. The mean height was 150.82 ± 22.44 cm, the mean weight was 34.71 ± 11.62 kg, and the mean BMI was 15.28 ± 4.25. Out of a total of 119 patients, 62.18% were underweight, 31.93% were healthy, and 5.88% were overweight. 55% of females and 68% of males were underweight. There is a statistically signifcant association between age and nutrition status (P=0.04). The data depicts a statistically significant association between family monthly income and nutrition status (P=0.013).
Conclusion. Results of this study showed that the majority of the children with thalassemia were underweight. There is a statistical association between age, economic status, and nutritional status. There is a need to raise awareness about food and nutrition for children with beta thalassemia major.
Keywords: thalassemia major, body mass index (BMI), underweight, nutrition.
Efcacy of Low-Intensity Aerobic Exercise and Aerobic Combined with Resistance Exercise on Pain, Respiratory Function, Fatigue and Qualityof Life in Nursing Patients
Authors: Kvietkauskas Šarūnas , Juodžbalienė Vilma 
Published: December 2023

Background. In older people with multiple comorbidities, quality of life declines due to physical deterioration, which may also contribute to psychological deterioration (Nóbrega et al., 2009; Subramaniam et al., 2019). In such cases, it is important to ensure adequate physical activity, as it can improve their physical and psychological condition (Bricca et al., 2020). Physical activity including aerobic exercises, resistance exercises, and stretching exercises can improve the quality of life in elderly (López-Torres, 2019), but it remains unclear which physical exercises are more effective.
The aim. To determine which of the physiotherapy programs - low-intensity aerobic exercises or combined aerobic and resistance exercises - are more effective in reducing pain and fatigue of nursing patients, improving respiratory indicators and quality of life.
Methods. 20 patients 74.85±5.4 years of age participated in the study. Subjects were randomly divided into two groups: MIAP group - applied low-intensity aerobic exercise, APP group - aerobic and resistance exercise. Perceived pain was assessed using numerical pain scale (SAS). Respiratory function indicators were evaluated by spirometry. The multidimensional fatigue inventory (MFI-20L) assessed general, physical and mental fatigue, decreased activity and motivation. The SF-36 questionnaire was used to assess the quality of life.
Results. Applying the MIAP and APP programs was significantly reduced pain, physical fatigue, improved quality of life related to physical and mental health, and respiratory indicators (p<0.05).
Conclusions. A low-intensity aerobic exercise program was more effective in reducing fatigue, while an aerobic and resistance exercise program was more effective in improving respiratory function. Both programs were effective in improving mental and physical health-related quality of life and reducing pain.
Keywords: physiotherapy, quality of life, pain, respiratory function, fatigue.
LINGUISTIC COMPLEXITY AND SIMPLIFICATION IN TRANSLATION: COGNITIVELY-GROUNDED PHONOLOGICAL METRICS
Authors: ALMIHMADI Mariam 
Published: December 2023

ABSTRACT

Translated text (TT) is characteristically simpler than non-translated (NTT) authentic text in terms of its lexicon, syntax, and style. It is still not clear what causes this phenomenon, and scholars continue to debate the issue. The traditional lexical metrics that are implemented in the simplification literature are often criticised as unreliable and lacking cognitive grounding. Moreover, being predominantly product-oriented, they cannot tell us how (or why) simplification happens. This paper addresses this limitation in the literature and proposes a paradigm that uses complexity-based measures adopted from Phonology and Cognitive Psychology. Calculations are run on a corpus of 100 translated and non-translated article abstracts drawn from five academic disciplines. Statistical analyses reveal significant differences between TTs and NTTs. The paper discusses the implications of these results and concludes that a cognition-informed approach is a key to demystifying simplification.

Keywords: linguistic complexity; simplification; phonological complexity; neighbourhood density, phonotactic probability
TRIGGERED CODE-SWITCHING: A BOTTOM-UP APPROACH TO CODE-SWITCHING AMONG L2 TEACHERS
Authors: CHONG Yin Sheun , SALEHUDDIN Khazriyati , AMZAH Normalis , ABDUL HAMID Bahiyah 
Published: December 2023

Classroom interaction in the second language (L2) is an important source of language
input for students. Yet, code-switching from the target language to another language is
commonplace in many L2 classrooms. Psycholinguistic studies have shown codeswitching
happens through top-down and bottom-up processes during bilingual speech
production. Triggering is a bottom-up process where code-switching is caused by words
that are shared between different languages. To investigate if triggered code-switching
takes place among secondary school ESL teachers in Malaysia, a study on teachers’
language use in class was conducted. A total of 111 minutes of interaction from two
English lessons was audio recorded and 225 instances of teacher code-switching in the
recordings were analysed. The analysis reveals that lexical transfers between English and
Malay and selected discourse markers triggered instances of code-switching among the
teachers. The findings suggest that teacher code-switching in L2 classrooms should be
considered from both top-down and bottom-up perspectives. Based on these findings,
suggestions for future studies on code-switching among L2 teachers were provided.