bluuebunny/crossref_metadata_2025_split huggingface dataset:
Treating infidelity: Clinical and ethical directions
Authors: Snyder Douglas K. , Doss Brian D. 
Published: September 2005

AbstractThis article addresses clinical and ethical directions in treating clients coping with infidelity. Developing competence in this domain requires familiarity with empirical research regarding infidelity, individual and cultural differences involving nonmonogamy, and assessment and intervention skills related to treating infidelity. Practical directions will entail distinguishing among responsibilities to individual partners versus their relationship and managing related potential conflicts of interest with other involved parties. Confidentiality assumes increased complexity when confronting undisclosed infidelity in couple therapy and when a client engaging in high‐risk behaviors for contracting STDs or testing seropositive for HIV has not informed his or her partner(s). Finally, we discuss therapists' need to concretely articulate their values that influence treatment of infidelity. © 2005 Wiley Periodicals, Inc. J Clin Psychol/In Session 61: 1453–1465, 2005.
Manganese‐enhanced MRI of the optic visual pathway and optic nerve injury in adult rats
Authors: Thuen Marte , Singstad Trond E. , Pedersen Tina Bugge , Haraldseth Olav , Berry Martin , Sandvig Axel , Brekken Christian 
Published: September 2005

AbstractPurposeTo evaluate manganese (Mn2+)‐enhanced MRI in a longitudinal study of normal and injured rat visual projections.Materials and MethodsMRI was performed 24 hours after unilateral intravitreal injection of MnCl2 (150 nmol) into adult Fischer rats that were divided into four groups: 1) controls (N = 5), 2) dose‐response (N = 10, 0.2–200 nmol), 3) time‐response with repeated MRI during 24–168 hours post injection (N = 4), and 4) optic nerve crush (ONC) immediately preceding the MnCl2 injection (N = 7). Control and ONC animals were reinjected with MnCl2 20 days after the first injection, and MRI was performed 24 hours later.ResultsIn the control group, the optic projection was visualized from the retina to the superior colliculus, with indications of transsynaptic transport to the cortex. There was a semilogarithmic relationship between the Mn2+ dose and Mn2+ enhancement from 4 to 200 nmol, and the enhancement decayed gradually to 0 by 168 hours. No Mn2+‐enhanced signal was detected distal to the ON crush site. In the control group, similar enhancement was obtained after the first and second MnCl2 injections, while in the ONC group the enhancement proximal to the crush site was reduced 20 days post lesion (20dpl).ConclusionMn2+‐enhanced MRI is a viable method for temporospatial visualization of normal and injured ON in the adult rat. The observed reduction in the Mn2+ signal proximal to the ONC is probably a result of retrograde damage to the retinal ganglion cells, and not of Mn2+ toxicity. J. Magn. Reson. Imaging 2005. © 2005 Wiley‐Liss, Inc.
Endovascular interventional MRI
Authors: Henk Christine B. , Higgins Charles B. , Saeed Maythem 
Published: September 2005

AbstractMR guidance has been used recently to navigate endovascular catheters and deliver stents in large (aorta and pulmonary) and small (coronary, renal, and femoral) arteries, place ASD closure devices, deliver pulmonary valve stents, guide cardiac RF ablations, and perform intramyocardial injections. However, MR visualization of a stent lumen is still a problem and requires more attention. Because of technical limitations and safety concerns associated with the prototype devices used, limited numbers of clinical studies have been performed. Considerable development is necessary to overcome the challenges and take advantage of the benefits that MR has to offer for endovascular interventions. In this article we review the current state of the art and address the topic partly by referring to our own experiments and presenting our recent illustrations. J. Magn. Reson. Imaging 2005. © 2005 Wiley‐Liss, Inc.
Pre‐ and postprandial alterations of portal venous flow: Evaluation with single breath‐hold three‐dimensional half‐fourier fast spin‐echo MR imaging and a selective inversion recovery tagging pulse
Authors: Tsukuda Toshinobu , Ito Katsuyoshi , Koike Shinji , Sasaki Katsumi , Shimizu Ayame , Fujita Takeshi , Miyazaki Mitsue , Kanazawa Hitoshi , Jo Chisaki , Matsunaga Naofumi 
Published: September 2005

AbstractPurposeTo evaluate the influence of food intake on portal flow using unenhanced magnetic resonance imaging (MRI).Materials and MethodsThe study population included 29 healthy subjects. A selective inversion recovery tagging pulse was used on the superior mesenteric vein (SMV) and splenic vein (SpV) to study the correlation of tagged blood in the portal vein (PV). MRI was performed before and 60–90 min after a meal.ResultsThe flow signal from the SMV increased in 97% of the subjects after the meal. Before the meal the portal flow was dominated by flow from the SpV in 59% of the subjects, while it was dominated by flow from the SMV in 76% of the subjects after the meal. The most common distribution pattern of the flow signal from the SpV before the meal was in the central part of the main PV (55%), while it was in the left side (45%) after the meal. The most common distribution pattern of the flow signal from the SMV was in the bilateral sides of the main PV both before and after the meal (62%).ConclusionThis technique shows potential for evaluating pre‐ and postprandial alterations of flow from the SpV and SMV in the PV under physiological conditions. J. Magn. Reson. Imaging 2005. © 2005 Wiley‐Liss, Inc.
3D volume‐selective turbo spin echo for carotid artery wall imaging with navigator detection of swallowing
Authors: Crowe Lindsey A. , Keegan Jennifer , Gatehouse Peter D. , Mohiaddin Raad H. , Varghese Anitha , Symmonds Karen , Cannell Timothy M. , Yang Guang Zhong , Firmin David N. 
Published: September 2005

AbstractPurposeTo improve 3D volume‐selective turbo spin echo (TSE) carotid artery wall imaging by incorporating navigators to reduce artifacts caused by swallowing.Materials and MethodsImages were acquired on a Siemens Magnetom Sonata 1.5T scanner. 3D volume‐selective TSE scans of the carotid arteries were acquired in six healthy volunteers. A cross‐pair navigator placed on the back of the tongue was used to detect swallowing and movement. Two swallowing patterns were tested: 1) a single swallow approximately halfway through the scan time, at the center of kz, and 2) repeated swallowing as often as possible throughout the scan period. Images were acquired with and without navigators for comparison. Signal intensity in the lumen was quantified for the quality of blood suppression, and the clarity of the vessel wall in the common carotid was ranked by four independent blinded observers.ResultsIn general, lower signal intensity was recorded in the lumen, and decreased blurring and ghosting were observed on scans with navigator control. This reduction in lumen signal intensity signifies an improvement in the black‐blood imaging technique. The differences likely reflect the improved double inversion/blood suppression efficiency due to cycles being rejected when the heart rate changed at the point of swallowing, or decreased motional blurring/ghosting of tissue when the navigator is used, or a combination of these two effects. A statistical analysis of image quality showed a significant difference between navigated and non‐navigated scans as scored by four independent, blinded observers. For both swallowing patterns, the mean score for the navigator images was on average 0.6 greater than that of non‐navigator images (on a scoring scale of 0–5, where 0 = no vessel visible, and 5 = good delineation and blood suppression) and P‐values for all observers were less than 0.01. Overall, the central swallow scans were scored higher than the repeated swallow scans. One reason for this may be the fact that the heart rate increased on swallowing, and this often lasted for one or two cardiac cycles after the navigator returned to the normal acceptance position. The effect of the increased heart rate after swallowing is likely to have an effect on double inversion blood suppression efficiency. Therefore, the increased amount of heart rate changes with repeated swallowing may have a greater adverse effect, even if the navigator rejects data views during the swallowing motion.ConclusionThe clarity of vessel wall delineation and the apparent efficiency of blood suppression are reduced by swallowing during acquisition. Both motion blurring and quality of blood suppression are factors that can be improved with the use of a navigator accept/reject method. J. Magn. Reson. Imaging 2005. © 2005 Wiley‐Liss, Inc.
Sensitivity encoding (SENSE) for contrast‐enhanced 3D MR angiography of the abdominal arteries
Authors: Born Markus , Willinek Winfried A. , Gieseke Jürgen , von Falkenhausen Marcus , Schild Hans , Kuhl Christiane K. 
Published: September 2005

AbstractPurposeTo assess sensitivity encoding (SENSE) for contrast‐enhanced MR angiography (CE‐MRA) of the abdominal arteries in comparison with standard MRA protocols.Materials and MethodsIn 22 patients MRA of the abdominal arteries was performed twice (once using a standard protocol, and once with the additional use of SENSE). In 10 patients all examination parameters were kept constant (TR/TE/FA = 3.8 msec/1.3 msec/30°), and a reduction in scan time from 22 to 11 seconds was realized with the use of SENSE. In 12 patients, using SENSE the acquisition matrix was increased from 208 to 416, keeping the scan time constant. Image quality was scored on a five‐point scale by three radiologists. Additionally, ROI‐based measurements of CNR were performed.ResultsFor both protocols, image quality was significantly improved using SENSE. The time‐reducing SENSE protocol yielded an average score of 4.2 points vs. 3.1 for the standard protocol. Using SENSE to increase the acquisition matrix, an average score of 4.3 was reached vs. 3.2 for the standard protocol (P < 0.05). The number of depictable small vessels and their bifurcations was significantly increased by either of the two SENSE protocols as compared to the standard imaging procedure.ConclusionSENSE for MRA of the abdominal arteries significantly increases image quality and permits a substantial reduction in breath‐hold time or a significantly improved spatial resolution. J. Magn. Reson. Imaging 2005. © 2005 Wiley‐Liss, Inc.
Gilles de la Tourette syndrome: Patient's knowledge and concern of adverse effects
Authors: Kompoliti Katie , Goetz Christopher G. , Morrissey Mary , Leurgans Sue 
Published: September 2005

AbstractThe objective of this study was to assess awareness and concern of neuroleptic (NL)‐induced side effects in Gilles de la Tourette syndrome (GTS) patients. Although NLs are effective tic suppressants, they can be associated with various side effects. Data on patient knowledge and concern about side effects can guide educational efforts. One hundred consecutive GTS patients or parents in a tertiary referral medical center responded to a standardized, in‐person questionnaire. They were given a list of 15 side effects and asked which could be ascribed to NLs (9) or not (6). Side effect concern was rated on a 0 (none) to 10 (extreme) scale. The mean age for the 100 patients was 19.4 ± 14 years; 55 had a history of NL use, and 45 were NL‐naive. Less than half the cohort met criteria for being well informed. Only one third of the listed NL side effects were accurately identified by at least 75% of the respondents. Patients with past or current NL treatment were more accurate in identifying NL side effects but less concerned about them than NL‐naive patients. The side effects of greatest concern were seizures, tardive dyskinesia, thinking and emotion disturbances, and cardiac irregularities. Overall, patient awareness of NL side effects is insufficient, and although past exposure to NLs enhances knowledge, it decreases concern. © 2005 Movement Disorder Society
Assessment of young children using the Achenbach System of Empirically Based Assessment (ASEBA)
Authors: Rescorla Leslie A. 
Published: September 2005

AbstractAfter providing a brief review of three other approaches to assessment of preschool children (DSM‐IV diagnoses, “Zero to Three” diagnoses, and temperament scales), this paper focuses on the Achenbach System of Empirically Based Assessment (ASEBA). The empirically based assessment paradigm provides user‐friendly, cost‐effective, reliable, and valid procedures for assessing children's behavioral/emotional problems from the perspectives of multiple informants. The ASEBA preschool forms, the Child Behavior Checklist for ages 1.5–5 (CBCL/1.5–5) and the Caregiver–Teacher Report Form (C–TRF), are usable by many different kinds of professionals in diverse settings. The CBCL/1.5–5 also includes the Language Development Survey (LDS), which provides a quick screen for delays in vocabulary and word combinations. The problem items of the CBCL/1.5–5 and the C–TRF are scored on both empirically based syndromes and DSM‐oriented scales, which are normed on the same general population sample. Variations in children's functioning across contexts and interaction partners make it essential to obtain and integrate data from multiple sources. Therefore, ASEBA software provides side‐by‐side comparisons of item and scale scores from up to eight assessment forms per child. Clinical and research applications of ASEBA preschool forms are summarized in the paper, and strengths and limitations are discussed. © 2005 Wiley‐Liss, Inc. MRDD Research Reviews 2005;11:226–237.
Assessment of motor development and function in preschool children
Authors: Tieman Beth L. , Palisano Robert J. , Sutlive Ann C. 
Published: September 2005

AbstractThe process of identification of children with delays or disorders in motor development includes developmental screening, examination, and reexamination. Throughout this process, various types of measures are used, including discriminative and evaluative measures. Discriminative and evaluative measures of motor development and function that are commonly used for preschool‐aged children include the Bayley Scales of Infant Development II, Peabody Developmental Motor Scales, 2nd edition, Toddler and Infant Motor Evaluation, Pediatric Evaluation of Disability Inventory, and Gross Motor Function Measure. Selecting an appropriate measure is a crucial part of the examination process and should be geared toward the purpose of testing and characteristics of the child. Evidence of reliability and validity are important considerations for selection of a measure. © 2005 Wiley‐Liss, Inc. MRDD Research Reviews 2005;11:189–196.
General measures of cognition for the preschool child
Authors: Lichtenberger Elizabeth O. 
Published: September 2005

AbstractPreschool‐age children who are experiencing delays in physical, cognitive, communication, social, emotional, or adaptive development are often referred for a comprehensive assessment to make diagnostic determinations and to help develop appropriate interventions. Typically cognitive assessment has a key role in a comprehensive evaluation of a young child. In this article, five individually administered tests of cognitive ability, normed for the preschool‐age child, are reviewed. These specific tests include the Bayley Scales of Infant Development, 2nd edition, the Kaufman Assessment Battery for Children, 2nd edition, the Wechsler Preschool and Primary Scale of Intelligence, 3rd edition, the Stanford‐Binet Intelligence Scale, 5th edition, and the Differential Abilities Scales. The following is provided for these cognitive instruments: a description of the test procedures, information on scoring systems, highlights of the technical qualities, and a summary of the general meaning of test results. The article concludes with strengths and limitations of the instruments. © 2005 Wiley‐Liss, Inc. MRDD Research Reviews 2005;11:197–208.
Assessment of social communication skills in preschoolers
Authors: Landa Rebecca J. 
Published: September 2005

AbstractThis paper orients the reader to social communication assessment and reviews methods for assessing social communication behavior in children from toddlerhood through the preschool years. Most standardized, normed tests of language in this age range focus on morpho‐syntactic and semantic comprehension and production abilities. While social communication is perhaps one of the most important skills for peer acceptance, these skills are often overlooked in language evaluation with children. However, there are a number of caregiver questionnaires, interviews, or direct social‐communication sampling methods that are available to assist clinicians or researchers in documenting social‐communication skills or behaviors. Since assessment of social communication is essential in clinical work with children with an autism spectrum disorder, some of the tools described below are outgrowths of autism research or provide autism‐related scores. While many children receiving social communication assessments do not have autism, the need to assess social communication skills in children with language impairment is highlighted by the growing literature documenting social and pragmatic difficulties in this population (Bishop 2000 Causes, Characteristics, Intervention, and Outcome. Hove, UK: Psychology press). Regardless of whether the measures presented herein were initially designed for children with autism or not, they will provide insights into the social communicative behaviors or tendencies in young children. © 2005 Wiley‐Liss, Inc. MRDD Research Reviews 2005;11:247–252.
Measurement of fiber orientation distributions using high angular resolution diffusion imaging
Authors: Anderson Adam W. 
Published: September 2005

AbstractHigh angular resolution measurements of diffusion are used to estimate the angular distribution and diffusion anisotropy of fibers in a voxel. A simple, axially symmetric model of diffusion in white matter fibers is used to relate diffusion measurements to fiber properties. The new technique is called fiber orientation estimated using continuous axially symmetric tensors (FORECAST). It is tested using both numerical simulation and in vivo measurements. The new method agrees with other methods in voxels containing single fibers, but resolves crossing fibers better, at least at the level of diffusion weighting used in this study (tr(b) = 1480 s/mm2). The simplifying assumptions of the model are tested by comparison with the “model‐free” q‐ball analysis of in vivo data and the results are shown to be in good agreement. The new method addresses the problem of partial volume averaging in diffusion tensor imaging and provides a basis for more reliable estimates of fiber orientation and fractional anisotropy. Magn Reson Med, 2005. © 2005 Wiley‐Liss, Inc.
On‐line identification of unstable iridoids from Jamesbrittenia fodina by HPLC–MS and HPLC–NMR
Authors: Cogne A.‐L. , Queiroz E. F. , Marston A. , Wolfender J.‐L. , Mavi S. , Hostettmann K. 
Published: September 2005

AbstractHPLC–UV–MS analysis of the methanol extract of Jamesbrittenia fodina (Wild) O. M. Hilliard (Scrophulariaceae) revealed the presence of different iridoid cinnamic esters; however, isolation of these constituents was prevented by instability problems. HPLC–UV–MS and HPLC–NMR analysis of the mixtures obtained after a tentative isolation indicated that, in the first instance, instability was due to a light‐induced cis/trans isomerisation of the cinnamic moieties. Further investigation of related compounds showed an additional instability problem linked to other chemical transformations. A detailed HPLC–NMR–MS study of these fractions demonstrated that the modifications occurred on the rhamnose moiety of these iridoids. It could be concluded that the second type of instability was attributable to transesterification of the cinnamic moiety on the rhamnose unit. The recording of stop‐flow HPLC–NMR spectra for specific HPLC peaks permitted the direct monitoring of these transformations. Based on these on‐line data, six new unstable aucubin derivatives were efficiently characterised. Copyright © 2005 John Wiley & Sons, Ltd.
Anomalies in the ionic properties of serum albumin
Authors: Salaman Myer R. , Warwicker Jim 
Published: September 2005

AbstractThe documented difference in the isoionic points of native and unfolded serum albumins is revisited with computational methods. Good agreement between calculated and measured ΔpIs is found, with the molecular origin appearing to reside in a diverse set of carboxyl group titrations. Although histidine ionization plays only a minor role in bringing about the ΔpI, the identification of three histidine residues with low computed pKas (around pH 5) suggests an explanation for the mismatch between experimentally derived group pKas and the pI of the native protein. Computed electrostatic properties (including pI) of native serum albumins are compared with a set of 178 nonenzyme proteins. We find that the degree of interdigitation of positive and negative charges is extreme for serum albumin, and discuss the relationship to protein solubility and pH‐dependent structural transitions. Proteins 2005. © 2005 Wiley‐Liss, Inc.
Oligomerization states of Bowman‐Birk inhibitor by atomic force microscopy and computational approaches
Authors: Silva Luciano P. , Azevedo Ricardo B. , Morais Paulo C. , Ventura Manuel M. , Freitas Sonia M. 
Published: September 2005

AbstractSeveral methods have been applied to study protein–protein interaction from structural and thermodynamic point of view. The present study reveals that atomic force microscopy (AFM), molecular modeling, and docking approaches represent alternative methods offering new strategy to investigate structural aspects in oligomerization process of proteinase inhibitors. The topography of the black‐eyed pea trypsin/chymotrypsin inhibitor (BTCI) was recorded by AFM and compared with computational rigid‐bodies docking approaches. Multimeric states of BTCI identified from AFM analysis showed globular–ellipsoidal shapes. Monomers, dimers, trimers, and hexamers were the most prominent molecular arrays observed in AFM images as evaluated by molecular volume calculations and corroborated by in silico docking and theoretical approaches. We therefore propose that BTCI adopts stable and well‐packed self‐assembled states in monomer–dimer–trimer–hexamer equilibrium. Although there are no correlation between specificity and packing efficiency among proteinases and proteinase inhibitors, the AFM and docked BTCI analyses suggest that these assemblies may exist in situ to play their potential function in oligomerization process. Proteins 2005. © 2005 Wiley‐Liss, Inc.
Modification of gamma ray induced changes in the mouse hepatocytes by Centella asiatica extract: in vivo studies
Authors: Sharma Radha , Sharma Jaimala 
Published: September 2005

AbstractIonizing radiation, besides causing direct damage also generates reactive oxygen species that are capable of inducing damage to various organs. Pretreatment with Centella asiatica 1 h prior to irradiation at a dose rate of 100 mg/kg body weight was found to be effective against radiation induced damage in the liver. The number of normal hepatocytes was higher in the Centella asiatica pretreated group in comparison with the irradiated only group. The number of binucleated cells and abnormal hepatocytes was less in comparison with the animals irradiated without Centella asiatica pretreatment. Copyright © 2005 John Wiley & Sons, Ltd.