bluuebunny/crossref_metadata_2025_split huggingface dataset:
Representación de la feminidad afroamericana en la ficción histórica estadounidense
Authors: Luis Maqueira Frida 
Published: January 2024

El presente artículo analiza la construcción y significación de la mujer afroamericana transgresora y la ubicuidad de los discursos hegemónicos en la representación audiovisual contemporánea que tematiza la experiencia de la feminidad negra en el pasado. Entre estas producciones audiovisuales se encuentran Criadas y Señoras (2011), Figuras Ocultas (2016), Harriet (2019) y Una mujer hecha a sí misma (2020). Con un enfoque interdisciplinar que conjuga la epistemología del feminismo negro con la semiótica, planteamos una aproximación interpretativa sobre las contradicciones y ambivalencias de la imagen femenina racializada en biopics y ficciones históricas. Nuestra investigación concluye que la construcción de la feminidad afroamericana está experimentando un periodo de transición en la industria audiovisual estadounidense, entre un nuevo discurso autoconsciente y la tendencia a situarla en una otredad instrumentalizada y mistificada.
Quercetin alleviates PM2.5-induced chronic lung injury in mice by targeting ferroptosis
Authors: Ding Shibin , Jiang Jinjin , Li Yang 
Published: January 2024

Background
PM2.5 is a well-known harmful air pollutant that can lead to acute exacerbation and aggravation of respiratory diseases. Although ferroptosis is involves in the pathological process of pulmonary disease, the potential mechanism of ferroptosis in PM2.5-caused lung inflammation and fibrosis need to be further clarified. Quercetin is a phenolic compound that can inhibit ferroptosis in various diseases. Hence, this study explores the role of ferroptosis in lung injury induced by PM2.5 in order to further elucidate the beneficial effect of quercetin and its underlying mechanism.

Methods
C57BL/6J mice were treated with either saline or PM2.5 by intratracheal instillation 20 times (once every two days). Additionally, PM2.5-treated mice were supplemented with two doses of quercetin. Lung injury, lipid peroxidation, iron content and ferroptosis marker protein expression and the Nrf2 signaling pathway were evaluated. In vitro, cell experiments were applied to verify the mechanisms underlying the links between Nrf2 signaling pathway activation and ferroptosis as well as between ferroptosis and inflammation.

Results
In vivo, PM2.5 increased lung inflammation and caused lung fibrosis and increased lipid peroxidation contents, iron contents and ferroptosis markers in lung tissues; these effects were significantly reversed by quercetin. Additionally, quercetin upregulated the nuclear Nrf2 expression and downregulated Keap1 expression in lung tissues of PM2.5-exposed mice. Quercetin decreased lipid peroxidation products, iron contents and ferroptosis levels and increased the nuclear translocation of Nrf2 and the degradation of Keap1 in PM2.5-exposed BEAS-2B cells. Moreover, we found that quercetin and dimethyl fumarate markedly decreased lipid peroxidation production and ferroptosis by activating the Nrf2-Keap1 pathway in PM2.5-exposed cells. Furthermore, quercetin reduced inflammatory cytokines and TGF-β1 in PM2.5-exposed cells.

Conclusion
Our data suggested that Nrf2 is involved in ferroptosis in PM2.5-induced lung injury, and quercetin can alleviate these adverse effects via activating Nrf2-Keap1 signaling pathway.
Proteomics-based screening of AKR1B1 as a therapeutic target and validation study for sepsis-associated acute kidney injury
Authors: Li Lei , Ling Zaiqin , Wang Xingsheng , Zhang Xinxin , Li Yun , Gao Guangsheng 
Published: January 2024

Background
Sepsis and sepsis-associated acute kidney injury (SA-AKI) pose significant global health challenges, necessitating the development of innovative therapeutic strategies. Dysregulated protein expression has been implicated in the initiation and progression of sepsis and SA-AKI. Identifying potential protein targets and modulating their expression is crucial for exploring alternative therapies.

Method
We established an SA-AKI rat model using cecum ligation perforation (CLP) and employed differential proteomic techniques to identify protein expression variations in kidney tissues. Aldose reductase (AKR1B1) emerged as a promising target. The SA-AKI rat model received treatment with the aldose reductase inhibitor (ARI), epalrestat. Blood urea nitrogen (BUN) and creatinine (CRE) levels, as well as IL-1β, IL-6 and TNF-α levels in the serum and kidney tissues, were monitored. Hematoxylin-eosin (H-E) staining and a pathological damage scoring scale assessed renal tissue damage, while protein blotting determined PKC (protein kinase C)/NF-κB pathway protein expression.

Result
Differential proteomics revealed significant downregulation of seven proteins and upregulation of 17 proteins in the SA-AKI rat model renal tissues. AKR1B1 protein expression was notably elevated, confirmed by Western blot. ARI prophylactic administration and ARI treatment groups exhibited reduced renal injury, low BUN and CRE levels and decreased IL-1β, IL-6 and TNF-α levels compared to the CLP group. These changes were statistically significant (P < 0.05). AKR1B1, PKC-α, and NF-κB protein expression levels were also lowered in the ARI prophylactic administration and ARI treatment groups compared to the CLP group (P < 0.05).

Conclusions
Epalrestat appeared to inhibit the PKC/NF-κB inflammatory pathway by inhibiting AKR1B1, resulting in reduced inflammatory cytokine levels in renal tissues and blood. This mitigated renal tissue injuries and improved the systemic inflammatory response in the severe sepsis rat model. Consequently, AKR1B1 holds promise as a target for treating sepsis-associated acute kidney injuries.
Corporate Governance and Financial Distress: A Comprehensive Analysis of Indonesian Manufacturing Companies
Authors: Abrori Safara Rodifah , Hendrawaty Ernie , Hasnawati Sri 
Published: January 2024

Aims: This study aims to find empirical evidence and analyze the effect of institutional ownership, managerial ownership, independent commissioner, board of directors, audit committe on financial distress. In addition, this research can also be used as a reference for further researchers as well as a reference for stakeholders (investors, creditors, and the government) in making relevant and reliable decisions.
Study Design: The method used is quantitative research with secondary data taken from the company's financial statements with data collection techniques using purposive sampling.
Place and Duration of Study: The study was conducted on 19 manufacturing companies listed on the Indonesia Stock Exchange for the period 2010 – 2021.
Methodology: The method used in this research is explanatory with a quantitative approach and the sampling used is purposive sampling. Explanatory analysis is used to explain the relationship between variables Institutional ownership, Managerial Ownership, Independent Commissioners, Board of Directors, Audit Committee.
Results: The results of this study indicate that: (1) Institutional Ownership have a negative effect on Financial Distress. (2) Managerial Ownership have a negative effect on effect on Financial Distress. (3) Independent Commissioners have a negative effect on effect on Financial Distress. (4) Board of Directors has a negative and significant effect on Financial Distress. (5) Audit Committee have no effect on Financial Distress.
Conclusion: Based on the conclusion of the effect of good corporate governance on financial distress, it can be seen that GCG implementation can improve company performance, especially financial performance and reduce the risk of financial distress and in general GCG implementation can increase investor confidence. Conversely, the implementation of low Corporate Governance will reduce investor confidence and can be a factor that prolongs the economic crisis.
Effects of Different Levels of Gamma Radiation on Growth and Yield Characteristics of Groundnut
Authors: Thenuja M. , Sutharsan S. , Rifnas L. M. 
Published: January 2024

One of the key strategy for improving the crops is plant mutation breeding, which generates a large germplasm pool to improve crop characteristics. In this field experiment, the effects of different levels of gamma radiation on the growth and yield characteristics of groundnut were investigated. "Gamma chamber 1200 Cobalt-60" research irradiator was used to irradiate the groundnut seeds. Two experiments were conducted, with the first exposing the seeds to gamma radiation levels ranging from 0 to 100 Gy, and the second exposing them to levels from 0 to 500 Gy. Irradiated seeds were sown in poly bags and kept under shade. After 2 weeks, seedlings were transplanted in an open field using a Randomized Complete Block Design with five replications. Growth and yield parameters were collected, and statistical analysis was carried out using SAS 9.1 software, with treatment means compared using DMRT at 0.05 level. Results from experiment one showed no significant (P ≥ 0.05) differences among treatments. However, in experiment two, treatments showed significant differences in the measured variables. Seeds exposed to 200 Gy had increased shoot fresh weight (123.3%), root fresh weight (69.8%), number of pods (46%), 100-seed weight (47.7%), and total yield (65.6%). The study recommends 200 Gy as a more suitable level of gamma radiation to create desirable characteristics in groundnut. In conclusion, gamma radiation can be an effective tool for inducing mutations in plants for crop improvement. The findings of this radiation study could contribute to the improvement of new cultivars of groundnut with desirable traits, such as increased yield and improved plant growth.
Genetic Diversity and Path Analysis in Rice Germplasms (Oryza sativa L.)
Authors: Vimal S. C. , Kumar Avanit , Gupta Rishabh , Gupta Ajeet Kumar , Singh Jay 
Published: January 2024

The present study was based on the germplasm evaluation experiment, which involved the evaluation of 45 germplasms/lines including three checks viz. NDR-97, NDR2065 and Saraju-52. The experiment was conducted in Augmented Block Design with three replications. The field experiment was carried out in Kharif season 2022 at the Crop Research Station (CRS), Masodha and lab experiments were conducted in the Seed Testing Laboratory, Seed Technology Section, Acharya Narendra Deva University of Agriculture and Technology, Kumarganj, Ayodhya (U.P.). The path coefficient analysis was worked out by using simple correlation among 13 characters to estimate the direct and indirect effect of different characters on grain yield per plant. The highest positive total effect (direct + indirect) on grain yield per plant was exhibited by panicle bearing tiller per plant (0.699) followed by germination % (0.360), seed viability (0.227) and vigour index – I (0.209). The highest number of genotypes appeared in the cluster – II (13), followed by cluster – III (8), cluster – IV(6), cluster – V(6), cluster – I(5), cluster – IX(5), cluster – VI(3), cluster – VII(1), and cluster – VIII(1). The maximum intra-cluster distance was observed in case of cluster – IX (64641.91) followed by cluster – V (5584.50), cluster – VI (5363.09), cluster – I (3918.44), cluster – II (3483.30), Cluster – IV (3303.54), Cluster – VII(0.00) and cluster – VII (0.00). The highest cluster mean for days to 50% flowering was recorded for Cluster-I (102.8) followed by Cluster – VII (99), cluster-V (96.66), cluster-VIII (96) cluster IX (96), Cluster III (95.75) cluster IV (95.65) cluster VI (94.67) cluster II (91.51).
Partial Heart Transplant in a Neonate With Irreparable Truncal Valve Dysfunction
Authors: Turek Joseph W. , Kang Lillian , Overbey Douglas M. , Carboni Michael P. , Rajab Taufiek K. 
Published: January 2024

ImportanceThe treatment of neonates with irreparable heart valve dysfunction remains an unsolved problem because there are no heart valve implants that grow. Therefore, neonates with heart valve implants are committed to recurrent implant exchanges until an adult-sized valve can fit.ObjectiveTo deliver the first heart valve implant that grows.Design, Setting, and ParticipantsCase report from a pediatric referral center, with follow-up for more than 1 year. Participants were a recipient neonate with persistent truncus arteriosus and irreparable truncal valve dysfunction and a donor neonate with hypoxic-ischemic brain injury.InterventionFirst-in-human transplant of the part of the heart containing the aortic and pulmonary valves.Main Outcomes and MeasuresTransplanted valve growth and hemodynamic function.ResultsEchocardiography demonstrated adaptive growth and excellent hemodynamic function of the partial heart transplant valves.Conclusions and RelevanceIn this child, partial heart transplant delivered growing heart valve implants with a good outcome at age 1 year. Partial heart transplants may improve the treatment of neonates with irreparable heart valve dysfunction.
Angular Engineering Strategy for Enhanced Surface Nonlinear Frequency Conversion in Centrosymmetric Topological Semimetal HfGe0.92Te
Authors: Zhao Qiming , Chen Long , Liang Fei , Wang Shuxian , Wang Gang , Yu Haohai , Zhang Huaijin 
Published: January 2024

AbstractSurface nonlinear optics are essential for developments in integrated photonics and micro/nano optoelectronics. However, the nonlinear optical conversion efficiency on a surface is restricted by the finite nonlinear susceptibility of matter and the intrinsic atomic‐layered interaction length between light and matter. In this work, based on an angular engineering strategy, it is demonstrated that the centrosymmetric topological semimetal HfGe0.92Te crystal has a giant and anisotropic surface second‐order nonlinear susceptibility up to 5535 ± 308 pm V−1 and exhibits efficient and unprecedented second‐harmonic generation (SHG). The maximum optical conversion efficiency is found to be up to 3.75‰, which is 104 times higher than that obtained from a silicon surface. Because of the linear dispersion over a wide range of energies around the Dirac points, this high conversion efficiency can be maintained with SHG wavelengths ranging from the visible region (779 nm) to the deep‐UV region (257.5 nm). This study can facilitate the development of topological photonics and integrated nonlinear photonics based on topological semimetals.
Ordered Mesoporous Crystalline Frameworks Toward Promising Energy Applications
Authors: Li Jialong , Li Rongyao , Wang Wendi , Lan Kun , Zhao Dongyuan 
Published: January 2024

AbstractOrdered mesoporous crystalline frameworks (MCFs), which possess both functional frameworks and well‐defined porosity, receive considerable attention because of their unique properties including high surface areas, large pore sizes, tailored porous structures, and compositions. Construction of novel crystalline mesoporous architectures that allows for rich accessible active sites and efficient mass transfer is envisaged to offer ample opportunities for potential energy‐related applications. In this review, the rational synthesis, unique structures, and energy applications of MCFs are the main focus. After summarizing the synthetic approaches, an emphasis is placed on the delicate control of crystallites, mesophases, and nano‐architectures by concluding basic principles and showing representative examples. Afterward, the currently fabricated components of MCFs such as metals, metal oxides, metal sulfides, and metal–organic frameworks are described in sequence. Further, typical applications of MCFs in rechargeable batteries, supercapacitors, electrocatalysis, and photocatalysis are highlighted. This review ends with the possible development and synthetic challenges of MCFs as well as a future prospect for high‐efficiency energy applications, which underscores a pathway for developing advanced materials.
An Optical Artificial Synapse Based on Single‐Crystal Se‐Vacancy Bi2O2Se
Authors: Ren Xuanyu , He Xinxin , Li Xingqi , Li Yang , Gao Feng , Zhang Jia , Hu PingAn 
Published: January 2024

AbstractThe optical synaptic device is a novel nonvolatile memory device that combines optical sensing function with synaptic plasticity to simulate the basic biomimetic behaviors of the human visual system. It shows a great potential application in artificial vision. However, most of the current optical synaptic devices are either structurally special or complex, which are quite difficult to prepare especially for mass production. In this work, a submillimeter single‐crystal Bi2O2Se flake with selenium vacancies (Bi2O2Se‐VSe) grown by physical vapor deposition is presented. Upon the Bi2O2Se‐VSe flake, an optical synaptic device is designed with the persistent photoconductivity (PPC) effect induced by selenium vacancies. The device can simulate the biological synapses with an obvious synaptic plasticity. Moreover, an artificial vision system consisting of a 3 × 4 array of optical synaptic devices has been fabricated. The intensity of the image pattern can keep at a high memory level of 54.64% and 19.31% for 532 and 1060 nm waiting for 400 s after illumination of 100 s, which demonstrates the devices exhibit excellent image sensing, learning, and memory storage. This work opens up a new route for fabricating the optical synaptic device with a simple structure and provides new ideas for studying artificial vision systems.
Judicious Design of Pyridine‐Based Hosts for Stable, Efficient, and Low‐Driving Thermally Activated Delayed Fluorescence Organic Light‐Emitting Diodes
Authors: Hu Yanmei , Civil Alexander , Li Yufang , Lestanto Gerardus N. Iswara , Tsuchiya Youichi , Chan Chin‐Yiu , Adachi Chihaya 
Published: January 2024

AbstractAlthough thermally activated delayed fluorescence (TADF) based organic light‐emitting diodes (OLEDs) continue to achieve high efficiencies, their device stability still does not necessarily meet industrial standards. To improve device stability, careful design of a stable host material is crucial. Herein, with reference to a common p‐type host material, 3,3′‐di(9H‐carbazol‐9‐yl)‐1,1′‐biphenyl (mCBP), three novel host materials based on a pyridine unit, mCBP‐1N, CzPyPhCz, and CzPyBF, are systematically designed to improve the stabilities efficiently. The green and blue TADF OLEDs are fabricated with these three new hosts. The maximum external quantum efficiencies (EQEmaxs) of green OLEDs are 20.3 % and 14.0% for CzPyBF and mCBP hosts, respectively. Further, high EQEs of 19.2% and 12.9% are maintained even at 1000 cd m−2. Most importantly, the device lifetime of the CzPyBF host can achieve LT95 of 62.7 h, which is 2.5 times longer than that of mCBP. Also, lower turn‐on voltages are achieved by using CzPyPhCz in blue and green devices. With host engineering, the TADF OLEDs are simultaneously improved with lower turn‐on voltages, higher EQEs, and longer device lifetimes.
Biomass Photothermal Hydrogel Based on Tea Leaves Residue for Cogeneration of Clean Water and Electricity
Authors: Jia Tao , Han Feng , Zhang Ruoyu , Zhao Meng , Chen Zhifei , Wang Zening , Li Lei , Qi Shuo , Xi Gaolei , Li Bin 
Published: January 2024

AbstractInterfacial solar‐driven evaporation has attracted much attention due to its high photothermal conversion efficiency. The core technology of photothermal conversion is photothermal materials, biomass photothermal materials are characterized by low cost, large specific surface area, environmental friendliness, and renewability. Discarded tea leaf residue (TLR) is harmful to the environment and has good recycling potential. In this work, a high‐performance, low‐cost, environmentally friendly solar steam generation material is fabricated by combining polyvinyl alcohol hydrogels and biomass photothermal material TLR. TheTLR hydrogel utilizes solar energy as a renewable energy source for desalination. Under 1.0 kW m−2 simulated solar irradiation, the evaporation rate is 1.35 kg m−2 h−1 and the evaporation efficiency is 93.35%. The waste heat generated during solar water evaporation can be effectively used for synergistic water‐electricity cogeneration, thus achieving an evaporation rate and voltage of 0.91 kg m−2 h−1 and 58.8 mV under 1.0 kW m−2 solar irradiation, respectively. The prepared hydrogel can also be used as a good organic dye adsorbent material, which has a broad application prospect in wastewater treatment. This method for preparing solar absorbers reduces manufacturing costs environmentally friendly and guides the potential practical application using discarded waste.
Association of individual comorbidities with outcomes in allogeneic hematopoietic cell transplantation from unrelated adult donors versus unrelated cord blood: A study on behalf of the Donor/Source and Transplant Complications Working Groups of the Japanese Society for Transplantation and Cellular Therapy
Authors: Konuma Takaaki , Harada Kaito , Shinohara Akihito , Uchida Naoyuki , Shingai Naoki , Ito Ayumu , Ozawa Yukiyasu , Tanaka Masatsugu , Sawa Masashi , Onizuka Makoto , Katayama Yuta , Hiramoto Nobuhiro , Nakano Nobuaki , Kimura Takafumi , Kanda Yoshinobu , Fukuda Takahiro , Atsuta Yoshiko , Nakasone Hideki , Kanda Junya 
Published: January 2024

AbstractWe retrospectively evaluated the effect of 17 individual comorbidities, defined by the hematopoietic cell transplantation (HCT)‐specific comorbidity index, on non‐relapse mortality (NRM) and overall survival (OS) in 9531 patients aged between 16 and 70 years who underwent their first allogeneic HCT from 8/8 and 7/8 allele‐matched unrelated donors (8/8 and 7/8 MUDs) or single‐unit unrelated cord blood (UCB) between 2011 and 2020 using data from a Japanese registry database. In the multivariate analysis, infection (adjusted hazard ratio [HR], 1.62, 95% confidence interval [CI], 1.33–1.99 for 8/8 and 7/8 MUDs; adjusted HR, 1.33, 95%CI, 1.12–1.58 for UCB) and moderate/severe hepatic comorbidity (adjusted HR, 1.57, 95%CI, 1.04–2.38 for 8/8 and 7/8 MUDs; adjusted HR, 1.53, 95%CI, 1.09–2.15 for UCB) had a significant impact on NRM in both donor groups. Cardiac comorbidity (adjusted HR, 1.40, 95%CI, 1.08–1.80), mild hepatic comorbidity (adjusted HR, 1.22, 95%CI, 1.01–1.48), rheumatologic comorbidity (adjusted HR, 1.67, 95%CI, 1.11–2.51), renal comorbidity (adjusted HR, 2.44, 95%CI, 1.46–4.09), and severe pulmonary comorbidity (adjusted HR, 1.40, 95%CI, 1.11–1.77) were significantly associated with an increased risk of NRM but only in UCB recipients. Renal comorbidity had the strongest impact on poor OS in both donor groups (adjusted HR, 1.73, 95%CI, 1.10–2.72 for 8/8 and 7/8 MUDs; adjusted HR, 2.24, 95%CI, 1.54–3.24 for UCB). Therefore, unrelated donor selection should be taken into consideration along with the presence of specific comorbidities, such as cardiac, rheumatologic, renal, mild hepatic, and severe pulmonary comorbidities.