bluuebunny/crossref_metadata_2025_split huggingface dataset:
Associations between daily affective experiences, trait and daily rumination on negative and positive affect: a diary study
Authors: Kovács Lilla Nóra , Kocsel Natália , Tóth Zsófia , Smahajcsik‐Szabó Tamás , Karsai Szilvia , Kökönyei Gyöngyi 
Published: October 2023

AbstractBackgroundRumination has mostly been studied in relation to depression, however, it may also occur in response to positive emotions (i.e., positive rumination) and therefore may be a protective factor related to the maintenance of positive mood.ObjectiveWe hypothesized that daily positive and negative affect would be associated with daily positive and negative rumination even after controlling for trait‐level rumination.MethodWe carried out a diary study with university students (n = 178), where participants had to answer short surveys online about their daily affect and daily rumination every evening for 10 days. We analyzed our data with multilevel regression in R.ResultsDaily positive and negative affect were significantly associated with daily negative and positive rumination, while trait‐level rumination scores were not. Daily and trait‐level rumination were moderately correlated (r = 0.333–0.440).ConclusionsOur findings highlight that daily rumination plays a more significant role in daily emotional experiences than trait rumination across positive and negative valence domains. Daily negative affect appears to be more closely related to higher daily negative rumination than the lack of daily positive rumination, which could be relevant for intervention strategies.
Description of two new species of Nostoc (Nostocales, Cyanobacteria) from central Mexico, using morphological, ecological, and molecular attributes
Authors: Carmona Jiménez Javier , Caro Borrero Angela , Becerra‐Absalón Itzel , Perona Urizar Elvira , Márquez Santamaría Kenia , Mateo Ortega Pilar 
Published: October 2023

AbstractThe present study describes two new Nostoc species, N. montejanii and N. tlalocii, based on a polyphasic approach that combines morphological, ecological, and genetic characteristics. The five investigated populations, including those from newly collected material from central Mexico, were observed to possess morphological features characteristic of the Nostoc genus. Results showed that both new species are strictly associated with running water, and they show clear differences in their habitat preferences. The 16S rRNA gene sequences of the five strains displayed between 98% and 99% similarity to the genus Nostoc sensu stricto. The 16S rRNA gene phylogenetic analyses inferred using Bayesian inference, maximum likelihood, and parsimony methods, placed these five strains in two separate clades distinct from other Nostoc species. The secondary structures of the 16S–23S internal transcribed spacer rRNA region in the two new species showed >10.5% dissimilarities in the operons when compared with other Nostoc species. In addition, clear morphological differences were observed between the two Mexican species, including the color of the colonies (black in N. montejanii and green in N. tlalocii), the size of the cells (greater in N. montejanii), and the number of polyphosphate granules present in the cells (one in N. montejanii and up to four in N. tlalocii).
Prurigo‐like atopic dermatitis in a child with CARD11‐associated severe combined immunodeficiency successfully treated with dupilumab
Authors: Gualdi Giulio , Lougaris Vassilios , Amerio Paolo , Petruzzellis Alessandra , Parodi Aurora , Burlando Martina 
Published: October 2023

AbstractA 12‐year‐old boy affected by severe combined immunodeficiency due to a heterozygous variant in the CARD domain of CARD11, c.169G>A; p.Glu57Lys, developed severe atopic dermatitis and alopecia areata. After failure of conventional systemic therapy, dupilumab was administered at a dose of 400 mg subcutaneously, followed by 200 mg every 14 days. The patient had an excellent clinical response after 1 month and complete remission after a year, with the absence of side effects, demonstrating good efficacy and safety profile.
Surgical outcome and prognosis of pediatric solid‐pseudopapillary neoplasm
Authors: Kawakubo Naonori , Takemoto Junkichi , Irie Keiko , Souzaki Ryota , Maniwa Junnosuke , Obata Satoshi , Yoshimaru Koichiro , Nagata Kouji , Miyata Junko , Matsuura Toshiharu , Tajiri Tatsuro 
Published: October 2023

AbstractBackgroundThe aim of this study was to clarify the characteristics and outcomes of pediatric patients with solid pseudopapillary neoplasms (SPNs) who underwent pancreatectomy.MethodsPediatric patients with SPNs who underwent pancreatectomy at our institution between 1995 and 2020 were included in the study.ResultsDuring the period under review, 12 patients underwent pancreatectomy for SPNs (median age: 10 years; range: 6–15 years). The surgical procedures included pancreatoduodenectomy (n = 2; 16.6%), distal pancreatectomy (n = 3; 25%), and enucleation (n = 7; 58.3%). The most common postoperative complication was postoperative pancreatic fistula (n = 6; 50%). Patients who underwent enucleation tended to have higher postoperative complication rates compared with those who underwent other procedures. All patients were alive without recurrence at the end of the study period.ConclusionsSPN is associated with a good prognosis, regardless of the surgical procedure. If surgeons select enucleation for pediatric SPNs, they should bear in mind that it is associated with a higher complication rate.
Association of surfactant protein A2 with acute respiratory failure in children
Authors: Emery Lucy , Kane Elizabeth , Anderson‐Fears Keenan , Liu Dajiang , Floros Joanna , Gandhi Chintan K. 
Published: October 2023

AbstractBackgroundInteractions among single nucleotide polymorphisms (SNPs) of surfactant protein (SP) are associated with acute respiratory failure (ARF) and its short‐term outcome, pulmonary dysfunction at discharge (PDAD) in children. However, genetic association studies using individual SNPs have not been conducted before. We hypothesize that SP genetic variants are associated with pediatric ARF and its short‐term complications by themselves.MethodsWe used available genotype and clinical data in the Floros biobank consisting of 248 children aged ≤24 months with ARF; 86 developed PDAD. A logistic regression analysis was performed for each of the 14 selected SNPs, SP‐A1 and SP‐A2 genotypes. A p‐value less than the Bonferroni correction threshold was considered significant. A likelihood ratio test was done to compare two models (one with demographic data and another with genetic variants).ResultsBefore Bonferroni correction, female sex is associated with a decreased risk of ARF. Black race and the rs721917 of the SFTPD are associated with increased risk of ARF. After Bonferroni correction, the 1A01A1 genotype of SFTPA2 was associated with decreased risk of ARF. The likelihood ratio test showed that the model of the genotype information with demographic data was a better fit to predict ARF risk. None of the SP SNPs and SP‐A1, SP‐A2 genotypes were associated with PDAD.ConclusionOur results indicate that SNPs and genotypes of SPs involved in innate immunity and host defense play an important role in ARF and, in the future, may be used as biomarkers.
Uterine prolapse in a non‐pregnant bitch
Authors: Greiling Marie Sophie , Packeiser Eva‐Maria , Gerhauser Ingo , Goericke‐Pesch Sandra 
Published: October 2023

AbstractA ten‐year‐old mixed breed bitch was presented for a tissue prolapse protruding from her vulva. Following detailed examination and stabilization, the ovaries and uterine horns were removed by laparotomy, whereas the prolapsed tissue identified as uterus including cervix was removed vaginally. Histology confirmed uterine prolapse, a rare condition in bitches usually found shortly after birth especially due to dystocia. In contrast, the present case was found in a nulliparous non‐pregnant bitch. Diagnostic and therapeutic approaches, including microbiological and histological findings, are described and discussed critically.
Importer market power and preferential trade agreements: Empirical evidence
Authors: Jestrab Ross 
Published: October 2023

AbstractThis paper provides direct empirical evidence that preferential trade agreements (PTAs) are consistent with the terms‐of‐trade theory. Using PTAs that occur between 2001 and 2015, we first show a PTA is associated with being more likely if countries have greater importer market power over one another. Second, using recently available tariff data for 39 bilateral PTAs, we show high levels of importer market power lead to tariff cuts that are larger in magnitude when PTAs enter into force. These results provide a rationale for why PTAs are permitted by the World Trade Organization.
Ear keloids: An innovative 3‐steps combined treatment
Authors: Domenico Piccolo , Giuliana Crisman , Daniele Bollero , Bruno Bovani , Alessandro Gennai , Fabrizio Melfa , Matteo Tretti Clementoni , Claudio Conforti 
Published: October 2023

AbstractIntroductionAn excessive proliferation of fibroblasts and collagen synthesis after an injury may lead to a benign fibrous tumor, known as keloid, which does not regress spontaneously. Earlobes are a very frequent site of onset, since after a trauma (i.e., piercing) keloids may develop either on the helix and on the anterior or posterior lobe, from a few months up to several years after the injury.ObjectivesTo report the effectiveness of a combined protocol of CO2 laser + Dye laser + a portable Blue LED Light medical device for Photobiomodulation Therapy (EmoLED®).MethodsFifty‐two patients with a total of 56 ear keloids have been treated in the same session with a single CO2 laser procedure + a pulsed Dye laser procedure with an adjunctive EmoLED® procedure for 3 up to 6 min. A monthly follow‐up has been performed with an adjunctive EmoLED® session in case of signs of inflammation.ResultsAmong 56 treated keloids, 89.3% of them (50/56) did not recur during a follow‐up period (from 6 up to 24 months, mean 16.3 months) while six keloids recurred (6/56, 10.7%) with mild thickening of the scar, thus requiring further treatments.ConclusionsEven if an excellent outcome obtained by the synergistic effect of combined laser treatments has already been described (i.e., CO2 laser + Dye Laser), the present study showed the adjuvant procedure with EmoLED® can reduce significantly the risk of keloids recurrences.
Quantitative Definition of Spray Edge With Extinction Diagnostics and Evaluation of Attenuation Coefficient for Liquid Jets in Supersonic Crossflow
Authors: McKelvy Aubrey J. , Braun James , Paniagua Guillermo , Andre Thierry , Choquet Etienne , Falempin Francois 
Published: October 2023

Abstract
A quantifiable, reproducible, and repeatable definition of the three-dimensional spray width and depth for a canonical jet in an open-source supersonic crossflow is presented. An expanding Mach 2 dry-air crossflow is generated through a converging-diverging nozzle with a 25.4 mm by 230 mm wide throat area. A one-millimeter injector with ethanol seeding provides the liquid injection. Injector characteristics and losses are quantified through a calibrated cavitating venturi. Momentum flux ratios ranged from 0.1 to 20, and Reynolds number scaled by the injector diameter ranged from 5000 to 40,000. A shadowgraph setup with a telecentric lens provides uniform magnification for precise and repeatable measurements from injection to 150 mm downstream of the jet. A Phantom v2012 camera with a frame rate of 20 kHz and shutter time of 285 ns was employed. Light transmittance is defined and calculated for each image pixel with a ratio method paired with no-spray images collected immediately before injection. These values are then related to an attenuation coefficient by incorporating spray width profiles collected with cross-sectional Mie-scatter imaging at multiple axial locations with a burst mode laser.
Thermal Inactivation of Airborne SARS-CoV-2 by an Electric Fan Heater in Winter and Defining Conditions to Ensure That All the Air Passes Through the Fan
Authors: Canpolat Murat , Şakalar Çağrı , Bozkurt Serhat , Çoban Ahmet Yılmaz , Karaçaylı Deniz , Toker Emre 
Published: October 2023

Abstract
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is spread, especially in closed environments, by airborne transmission. The study aims to assess the thermal inactivation of airborne SARS-CoV-2 in a 30 m3 test room as a function of outlet temperature, airflow rate, and operating time of an electric heater, then define a condition to ensure that all air in the room passes through the electric heater. Aerosolized SARS-CoV-2 was delivered to the test room at an ambient temperature of 20 °C and 40% humidity. Two electric heaters with different powers and airflow rates were operated respectively in the test room to compare their efficiencies in the inactivation of airborne SARS-CoV-2. The first and second electric heaters had power, airflow rates, and outlet temperatures of 1.5 kW, 44 m3/h, 220 °C, and 3 kW, 324 m3/h, and 150 °C, respectively. A fan drew the outside air into the heater. In the first experiment, a 1.5 kW electric heater was operated in the test room for 80 min. In the second experiment, a 3 kW electric heater was used in the test room for 75 min. Airborne SARS-CoV-2 in the test room was inactivated by 99.00% and 99.96% in the first and second experiments, respectively. A condition is defined to ensure that all the air in the room passes at least once through the electric heater fan.
“It Looks Good on Paper, But It Was Never Meant to Be Real”: Mixed-Gender Events in the Paralympic Movement
Authors: Dean Nikolaus A. , Bundon Andrea , Howe P. David , Abele Natalie 
Published: October 2023

Although the Paralympic Games have been around for over 60 years, women remain underrepresented in almost all aspects of the Paralympic Movement. It has been suggested that a way to increase women’s involvement is through the implementation of mixed-gender events. On paper, this approach makes sense. However, when it comes to the implementation of mixed-gender opportunities for women, it is less clear how effective these events are in increasing participation by women in Para sport. Through document analysis and interviews with athletes and organizers of mixed-gender Paralympic sport, we explore the various strategies that four mixed-gender sports have used to address the issue of gender parity. Using critical feminist theories, we illustrate how larger social, political, and cultural ideas about gender influence women’s experiences within these events and discuss the potential of using mixed-gender initiatives to address gender parity within the Paralympic Movement.
Plasmid-encoded VCC-1 β-lactamase in a clinical isolate of
Aeromonas caviae
Authors: Bychenko Banyas Darya , Lurie-Weinberger Mor , Efrati Epchtien Reut , Laviad Shitrit Sivan , Temkin Elizabeth , Schwartz David , Keren-Paz Alona , Carmeli Yehuda 
Published: October 2023

ABSTRACT

V
ibrio
c
holerae

c
arbapenemase (VCC-1) is a chromosomal encoded class A carbapenemase thus far reported in environmental
Vibrio cholerae
isolates. Here, we report the first isolation of a

bla
VCC-1

-carrying
Aeromonas caviae
from a clinical sample in Israel. The isolate was resistant to all β-lactam agents, including carbapenems. The

bla
VCC-1

was located on a large plasmid. GC content suggests that the origin of the

bla
VCC-1

gene is neither
Aeromonas
nor
Vibrio
spp. but an unknown progenitor.
In vitro
activity of imipenem/relebactam against
Pseudomonas aeruginosa
isolated from patients with cystic fibrosis
Authors: Ruiz Victor H. , Fratoni Andrew , Nicolau David P. , Kuti Joseph L. 
Published: October 2023

ABSTRACT

Pseudomonas aeruginosa
is a common multidrug-resistant pathogen in patients with cystic fibrosis (CF). The
in vitro
activity of imipenem/relebactam and imipenem was compared with other antipseudomonal antibiotics against 105 isolates from patients with CF from three US hospitals. Imipenem/relebactam, imipenem, meropenem, ceftazidime/avibactam, and ceftolozane/tazobactam susceptibilities were 77%, 55%, 58%, 90%, and 92%, respectively. Relebactam potentiates imipenem against CF
P. aeruginosa
by fourfold leading imipenem/relebactam to retain susceptibility against most isolates in this cohort.
Multiplexed on-site sample-in-result-out test through microfluidic real-time PCR (MONITOR) for the detection of multiple pathogens causing influenza-like illness
Authors: Yang Yi , Wang Chao , Shi Hua , Guo Xudong , Liu Wanying , Li Jinhui , Li Lizhong , Zhao Jun , Zhang Guohao , Song Hongbin , Hao Rongzhang , Zhao Rongtao 
Published: October 2023

ABSTRACT

The global COVID-19 pandemic and frequent outbreaks of other infectious diseases, such as influenza and monkeypox, often initially manifest with non-specific influenza-like symptoms. Portability to the outbreak site and accurate identification of the various pathogens causing influenza-like illness are crucial for the rapid implementation of effective control measures. Utilizing real-time PCR and microfluidic technology, a multiplexed on-site sample-in-result-out test through microfluidic real-time PCR (MONITOR) has been developed for detecting the pathogens responsible for influenza-like illness. The operator simply needs to introduce the sample to a highly integrated microfluidic chip (requiring ≤1 minute), and the system can autonomously execute sample pre-processing, nucleic acid extraction, and PCR amplification and deliver results for eight pathogens within 85 minutes. The detection limit of MONITOR for the eight pathogens ranges from 0.78 to 6.25 copies/µL. Standard curves demonstrate notable linearity and amplification efficiency. A simulated clinical sample test reveals MONITOR’s sensitivity, specificity, and accuracy at 97.5%, 100%, and 98%, respectively. Bland-Altman analysis demonstrates strong agreement between the cycle threshold of positive MONITOR samples and quantitative polymerase chain reaction (qPCR) (
R
2
= 0.952), suggesting MONITOR’s ability to indirectly quantify pathogen load. The fully enclosed structure of the system chip minimizes sample and environmental cross-contamination, rendering the assay independent of a specialized laboratory. The portable, fully automated MONITOR facilitates on-site, comprehensive detection of multiple pathogens, even non-specialized operators with minimal training. This presents a promising approach for the rapid and precise diagnosis of influenza-like illness in grassroots communities and underserved rural areas lacking centralized laboratories.

IMPORTANCE
This study combines quantitative polymerase chain reaction (qPCR) and microfluidics to introduce MONITOR, a portable field detection system for multiple pathogens causing influenza-like illness. MONITOR can be rapidly deployed to enable simultaneous sample-in-result-out detection of eight common influenza-like illness (ILI) pathogens with heightened sensitivity and specificity. It is particularly well suited for communities and regions without centralized laboratories, offering robust technical support for the prompt and accurate monitoring and detection of ILI. It holds the potential to be a potent tool in the early detection and prevention of infectious diseases.
Parallel evolution of picobirnaviruses from distinct ancestral origins
Authors: Perez Lester J. , Cloherty Gavin A. , Berg Michael G. 
Published: October 2023

ABSTRACT

Picobirnaviruses (PBVs) are small, bi-segmented, double-stranded RNA viruses frequently associated with gastrointestinal and recently linked to respiratory infections. Detected in hosts from distant biological kingdoms, debate swirls as to their age and origins and whether they are prokaryotic or eukaryotic viruses. Our evolutionary analysis revealed a contemporaneous emergence for PBV, as PBV-R
1&3
species arose ~350 years ago with both segments, whereas the more ancient species, PBV-R
2
, initially lacked capsid. Integrated phylogenetic reconstruction defined two origins for PBV, determining PBV-R
1&3
species descended from
Reovirus
and PBV-R
2
branched with
Partitivirus
ancestors. These results, coupled with the heterogeneity of Shine-Dalgarno motifs, argue against a prokaryotic origin. Epistatic interactions identified in the RdRp of PBV-R
1&3
evidenced the constraints imposed by vertebrate host immunity, whereas its absence in PBV-R
2
concurs with its fungal origin. After acquisition of capsid, PBV-R
2
increased its adaptive and functional divergences in RdRp domains and the compactness of its RNA structure to enable encapsidation. While their pathogenicity remains an open question, picobirnaviruses likely originated from both fungal and avian hosts: parallel evolution mechanisms have driven the genetic similarities shared among present-day PBV species.

IMPORTANCE

Picobirnaviruses (PBVs) are highly heterogeneous viruses encoding a capsid and RdRp. Detected in a wide variety of animals with and without disease, their association with gastrointestinal and respiratory infections, and consequently their public health importance, has rightly been questioned. Determining the “true” host of Picobirnavirus lies at the center of this debate, as evidence exists for them having both vertebrate and prokaryotic origins. Using integrated and time-stamped phylogenetic approaches, we show they are contemporaneous viruses descending from two different ancestors: avian
Reovirus
and fungal
Partitivirus
. The fungal PBV-R2 species emerged with a single segment (RdRp) until it acquired a capsid from vertebrate PBV-R1 and PBV-R3 species. Protein and RNA folding analyses revealed how the former came to resemble the latter over time. Thus, parallel evolution from disparate hosts has driven the adaptation and genetic diversification of the
Picobirnaviridae
family.