bluuebunny/crossref_metadata_2025_split huggingface dataset:
Bone health in children with primary hyperoxaluria type 1 following liver and kidney transplantation
Authors: Büscher Rainer , Pape Lars , Büscher Anja K. 
Published: February 2024

BackgroundPrimary hyperoxaluria type 1 is characterized by hepatic oxalate overproduction, leading to nephrocalcinosis, kidney stones, kidney failure and systemic oxalosis, including oxalate osteopathy. Combined liver-kidney transplantation (CLKT) and kidney after liver transplantation (KALT) were established therapeutic options to stop the devastating consequences of oxalate bone disease.MethodsWe describe a retrospective cohort of 10 children with PH1who were referred to our hospital from different countries for combined transplantation. Demographic and clinical data were collected and symptoms of bone disease, conventional radiological examinations, plasma oxalate levels and other determinants of calcium-phosphate metabolism were compared pre and post transplantation.ResultsTen patients (7 male, median age 5.8 years, median follow-up time 8.1 years) were included in this study. Seven patients were diagnosed with infantile oxalosis and 9 patients received an intensified dialysis regime prior to transplantation. In one patient the transplanted kidney never achieved primary function and the boy remained on HD. All other patients remained without graft failure and retained stable kidney and liver function. Prior to transplantation, seven patients suffered from severe skeletal pain and three children presented with 1–3 series of pathological fractures. Pathological fractures did no longer occur in children who underwent successful CLKT or KALT. Plasma oxalate levels dropped within 6 months following Tx. Determinants of calcium-phosphorus metabolism did not differ significantly in comparison to other HD children. Seven of ten children showed a restricted growth at the time of transplantation and presented a moderate catch-up-growth at the time of last follow-up.ConclusionsPatients with PH1 suffer from severe consequences of a disturbed bone metabolism. However, bone health and growth can partially improve following CLKT/KALT.
The Pro-197-Thr mutation in the ALS gene confers novel resistance patterns to ALS-inhibiting herbicides in Bromus japonicus in China
Authors: Liu Leicheng , Wu Lamei , Li Zongfang , Fang Yuhang , Ju Boming , Zhang Sisi , Bai Lianyang , Pan Lang 
Published: February 2024

IntroductionBromus japonicus is one of the most notorious agricultural weeds in China. The long-term use of ALS-inhibiting herbicides has led to rapid evolution of herbicide resistance in B. japonicus. B. japonicus population (BJ-R) surviving mesosulfuron-methyl treatment was collected from wheatland. Here, we aimed to confirm the resistance mechanisms in this putative resistant population.MethodsThe dose-reponse tests were used to test the resistance level of the B. japonicus to ALS-inhibiting herbicides. Pretreatment with P450 and GST inhibitors and GST activity assays were used to determine whether P450 or GST was involved in the resistance of the BJ-R population. Sanger sequencing was used to analyse the ALS mutation of the BJ-R population. RT-qPCR was used to confirm the the expression levels of the ALS gene in mesosulfuron-methyl -resistant (BJ-R) and-susceptible (BJ-S) B. japonicus. An in vitro ALS activity assay was used to determine the ALS activity of the BJ-R and BJ-S populations. Homology modelling and docking were used to determine the binding energy of the BJ-R and BJ-S populations with ALS-inhibiting herbicides.ResultsB. japonicus population (BJ-R) was confirmed to be 454- and 2.7-fold resistant to the SU herbicides mesosulfuron-methyl and nicosulfuron, and 7.3-, 2.3-, 1.1- and 10.8-fold resistant to the IMI herbicide imazamox, the TP herbicide penoxsulam, the PTB herbicide pyribenzoxim and the SCT herbicide flucarbazone-sodium, respectively, compared with its susceptible counterpart (BJ-S). Neither a P450 inhibitor nor a GST inhibitor could reverse the level of resistance to mesosulfuron-methyl in BJ-R. In addition, no significant differences in GST activity were found between the BJ-R and BJ-S. ALS gene sequencing revealed a Pro-197-Thr mutation in BJ-R, and the gene expression had no significant differences between the BJ-R and BJ-S. The ALS activity of BJ-R was 106-fold more tolerant to mesosulfuron-methyl than that of BJ-S. Molecular docking showed that the binding energy of the ALS active site and mesosulfuron-methyl was changed from -6.67 to -4.57 kcal mol-1 due to the mutation at position 197.DiscussionThese results suggested that the Pro-197-Thr mutation was the main reason for the high resistance level of BJ-R to mesosulfuron-methyl. Unlike previous reports of the cross-resistance pattern conferred by this mutation, we firstly documented that the Pro-197-Thr mutation confers broad cross-resistance spectrums to ALS-inhibiting herbicides in B. japonicus.
Stress, depression, and anxiety: psychological complaints across menopausal stages
Authors: Kuck Ming Jun , Hogervorst Eef 
Published: February 2024

IntroductionWith the number of menopausal women projected estimated to reach 1.2 billion by 2030 worldwide, it is critically important to understand how menopause may affect women’s emotional well-being and how many women are affected by this. This study aimed to explore (i) the relationship between psychological complaints (depression, anxiety, poor memory) across different menopausal stages and (ii) investigate the correlation between resilience, self-efficacy, and perceived stress levels, with psychological complaints and whether this was associated with menopausal stage and/or age.Methods287 respondents completed the Menopausal Quality of Life (MenQoL), Perceived Stress Scale (PSS-10), Brief Resilience Scale (BRS), and General Self-efficacy (GSE) scales. Parametric and non-parametric analysis were used to analyse how bothered women were by self-reported poor memory and feelings of depression and anxiety, alongside perceived stress, resilience, and self-efficacy between women in different menopausal stages using STRAW criteria. The association between protective factors (self-efficacy and resilience) and psychological complaints was analysed with partial correlation analysis controlling for menopausal stages and/or age.ResultsA significant difference was found between the levels of perceived stress, and how bothered women were by feelings of depression and anxiety between early-perimenopausal and post-menopausal women. However, with the inclusion of age as a covariate, menopausal stage no longer predicted the level of self-reported stress and anxiety in menopausal women. There was also no difference between poor self-reported memory, or of self-efficacy or resilience between women in different menopausal stages. However, self-efficacy and resilience were associated with how bothered women were by feelings of depression and anxiety, and the experience of stress. Stress was the only variable to be associated with poor self-reported memory independent of age and/or menopausal status.DiscussionEarly perimenopausal women experienced the highest level of stress and were more severely bothered by feelings of depression and anxiety, with the poorest overall self-reported psychosocial quality of life. Post-menopausal women, however, reported to have similar experiences as premenopausal women. Age explained the associations between menopausal stage, stress and anxiety, but not between depression and different menopausal stages. Resilience and self-efficacy were associated with psychological complaints independent of menopausal stage and age, suggesting that therapies focusing on increasing resilience and self-efficacy may be beneficial to help target these psychological complaints at any time.
Psychometric evaluation of the Chinese version of the fear of pregnancy scale: a translation and validation study
Authors: Wu Chunyan , Zhang Jian , Zhao Lei , Li Yanhong , Yan Yuanyuan , Wei Yue , Zhang Zhixia , Guo Shuming 
Published: February 2024

IntroductionMany women experience fear toward pregnancy, which can impact their desire to have children and the national birth rate. Thus, assessing women’s fear of pregnancy is of great importance. However, there is currently no specialized tool for assessing women’s fear of pregnancy in China. The purpose of this study is to translate the Fear of Pregnancy Scale into Chinese and test its reliability and validity among women of childbearing age.MethodsUsing convenience sampling combined with a snowballing method, a cross-sectional survey was conducted on 886 women of childbearing age in two cities in China. The translation was strictly carried out according to the Brislin model. Item analysis, validity analysis, and reliability analysis were employed for psychometric assessment.ResultsThe Chinese version of the Fear of Pregnancy Scale comprises 28 items. Exploratory factor analysis extracted four factors with a cumulative variance contribution rate of 72.578%. Confirmatory factor analysis showed: NFI = 0.956, CFI = 0.986, GFI = 0.927, IFI = 0.986, TLI = 0.985, RMSEA = 0.032, and χ2/df = 1.444. The scale’s Cronbach’s α coefficient is 0.957, split-half reliability is 0.840, and test–retest reliability is 0.932.ConclusionThe Chinese version of the Fear of Pregnancy Scale possesses robust psychometric properties and can assess the degree of pregnancy fear among Chinese women of childbearing age. It provides a reference for formulating relevant policies in the prenatal care service system and implementing targeted intervention measures.
Non-chemical management of weeds through bioherbicides: current status, market, development, constraints and future prospects
Authors: Aneja Kamal Roy 
Published: February 2024

A weed, a kind of pest, is a plant growing where it is not desired, or a plant out of its place. Weeds are a major threat to biodiversity and agricultural productivity. The annual losses caused by weeds has been estimated to over US$26 billion in the USA, AU$ 3.3 billion in Australia and US$ 11 billion in India exclusively in 10 major crops. The rising awareness about the potential health risk with chemical residues among individuals and farmers, emphasis is on growing organic crops to keep us healthy and a long life. In addition, the constant use of herbicides in agriculture system also paves the way for the emergence of resistance of weed variety. Bioherbicides, an eco-friendly alternative to non-chemical management of weeds, are defined as the formulations based on indigenous living host-specific microorganisms and ancillary components applied in an inundative manner similar to chemical herbicides. The term microbial herbicide preferably be used for microbial-based formulations. These are derived from fungi, bacteria and viruses. The bioherbicides market is rapidly growing and expected to witness market growth at a rate of 15% and is expected to reach US$1.84 by 2029. In spite of all efforts, acceptance of bioherbicides by the users is low due to a wide range of constraints (e.g., environmental, technological, host-specificity, regulatory, funding and human-related). Environmental conditions playing a significant role on the microbial germination, penetration, infection and biocontrol efficacy of the target host. Twenty-six microbe-based herbicides have been developed globally. At present, 13 bioherbicides are available in the market namely DeVineTM, CollegoTM (LockdownR), BioMalR, BioChonTM, MycoTechTM, Chontrol™ (EcoClearTM), SmolderR, SarritorTM, SolvinixR, Gibbartrianth, BiophomaTM and Di-Bak ParkinsoniaR. For successful deployment of bioherbicides into agriculture, horticulture and forestry, in addition to boosting their market, scientists need to develop consumer-friendly bioherbicides with a long-shelf life, non-effected by environmental conditions, ability to control varied weeds in a crop, and with a biocontrol efficacy better than or at par with the synthetic herbicides. Objective of this review is to discuss biocontrol strategies for controlling weeds, phases of bioherbicide development, market, current global status, development of currently available bioherbicides, constraints/limitations in their production & demand and future prospects for their adoption in weed management system.
Interpretable structure-property correlation in X-ray diffraction patterns of HfZrO thin films via machine learning
Authors: Feng Lei , Nakamura Takahiro , Ni Zeyuan 
Published: February 2024

Abstract
The X-ray diffraction (XRD) patterns of materials contain important and rich information in terms of structure, strain state, grain size, etc. The XRD can become a powerful fingerprint for material characterizations when it is combined with machine learning techniques. Attempts utilizing machine-learning-based methods mainly focus on phase identification for mixture compounds. Herein, we applied a machine-learning-based method linking XRD patterns of HfZrO thin films directly to their electronic properties in experiments. In accordance with conventional understanding, the machine learning model suggests that non-monoclinic (NM) phases of HfO2 and ZrO2 are among the main contributors to higher relative permittivity and lower leakage current. Furthermore, some minor interfacial phases like TiO
x
and ZrN
x
are also proposed to be even more important contributors to our target electronic properties. Our research demonstrates that machine learning has the potential to reveal minor XRD signals from sub-1 nm interfacial layers that have long been considered undetectable and thus ignored by human interpretation.
A simple reflective metalens based on reverse design for an ultra-high-efficiency free space wavelength splitter
Authors: Wang Chao , Hao Yunpeng , Wu Boqi , Yang Fan , Zhao Chunlei , Chi Yaodan , Yang Xiaotian 
Published: February 2024

Abstract
We propose two kinds of high-efficiency free-space wave splitters in the mid-IR band using reverse design. The wavelength divider based on the abnormal reflection principle realizes a beam-splitting angle of 22.00° and 10.92° by controlling the phase distribution, and the reflection efficiency of both wavelengths exceeds 50%. The wavelength divider designed based on the concept of metalens simultaneously accomplishes the functions of focusing and beam splitting. It has a focal length of 100 μm and a relative focal position of 100 μm. Most importantly, the focusing efficiency for the two wavelengths reaches an impressive 48.59% and 72.51%, respectively.
Gerakan Pelestarian Lingkungan Digital Memanfaatkan Blog Dengan Platform Wix Pada Siswa Madrasah Aliyah Al Azhar Asy Syarif Indonesia
Authors: Cholidhazia Putri , Rahayu Kun Mardiwati , Supriyanto Arif 
Published: February 2024

<p><em>Pelestarian lingkungan merupakan tantangan global yang menjadi tanggung jawab bersama.</em><em> Madrasah Aliyah Al Azhar Asy Syarif Indonesia</em><em> adalah sekolah yang </em><em>mendapatkan penyuluhan peduli lingkungan</em><em> dalam penumbuhan karakter siswa</em><em>. Namun siswa hanya sebagai penerima informasi belum adanya tindak lanjut dalam menyebarkan informasi terhadap pelestarian lingkungan</em><em>. Diikuti oleh dampak dari pembelajaran secara online pada saat Covid 19. Menimbulkan permasalahan yang mengakibatkan rendahnya kemampuan peserta didik dalam belajar terutama dalam kemampuan menulis. Saat ini perkembangan teknologi informasi dan komunikasi (TIK) terus berkembang. Terutama dalam mendukung budaya literasi menulis pada bidang pendidikan. Literasi digital menjadi sarana mengekspresikan ide dan pikiran dengan memanfaatkan internet sebagai akses dalam menyebarluaskan informasi secara luas, salah satunya media yaitu blog. </em><em>Blog merupakan salah satu layanan aplikasi dengan ruang untuk kegiatan menulis, mengajak dan memotivasi publik </em><em>untuk </em><em>berbagi pemikiran dan ide-ide dengan orang lain di seluruh dunia, serta memberikan kesempatan </em><em>salah satunya dalam</em><em> mempromosikan tindakan pelestarian lingkungan.</em><em> Salah satu platform interaktif dalam pembuatan blog yaitu wix.com. Oleh karena itu dilakukan penyuluhan dan pelatihan dalam menulis blog pada platform wix dengan tema pelestarian lingkungan. Kegiatan ini menghasilkan luaran yaitu jumlah blog tema pelestarian lingkungan yang berhasil dibuat oleh 25 siswa dari 30 siswa. Kemudian tingkat kepuasan peserta dalam pelatihan blog yaitu 91%.</em></p><strong>Kata kunci<em>:</em><em> Blog, Pelestarian Lingkungan, Wix,</em></strong>
ГЛОБАЛЬНІ МАКСИМУМИ ТА ОПТИМАЛЬНА ГЕОМЕТРІЯ АКУСТООПТИЧНОЇ ВЗАЄМОДІЇ У КРИСТАЛАХ ТРИГЛІЦИНСУЛЬФАТУ
Authors: О.А. Бурий  , М.А. Андрущак  , О.Д. Корнєєв  , Н.М. Дем’янишин  , Б.Г. Мицик  , А.С. Андрущак  
Published: February 2024

За методом екстремальних поверхонь визначені глобальні максимуми коефіцієнта акустооптичної якості M2 для моноклінного кристала тригліцинсульфату (NH2CH2COOH)3H2SO4 (TGS). Показано, що найбільше значення M2 становить 17.1×10-15 с3/кг та досягається у випадку ізотропної дифракції типу i®i на повільній квазіпоперечній акустичній хвилі. Встановлено, що максимум M2 реалізується при використанні непрямого зрізу кристала; визначено відповідні напрямки поширення та поляризації взаємодіючих світлової та акустичної хвиль.
ПОРІВНЯЛЬНО-ПРАВОВИЙ АНАЛІЗ ЗАКОНОДАВСТВА В ОБЛАСТІ ІНТЕЛЕКТУАЛЬНОЇ ВЛАСНОСТІ В КРАЇНАХ ЄС ТА УКРАЇНІ
Authors: Редько Р.Г. , Скляров Р.А. , Шанайда В.В. 
Published: February 2024

У матеріалах статті розглянуті основні напрями розвитку сучасного законодавства окремих країн Європи в сфері інтелектуальної власності (ІВ). Розглянуто та проаналізовано різноманітні шляхи адаптації законодавства різних країн Європи щодо інтелектуальної власності до вимог законодавства європейського союзу. Авторами встановлено, що законодавства ряду країн європейського союзу в питаннях захисту ІВ зберегли національні особливості по при загальну адаптацію до єдиного європейського законодавства у сфері патентування та єдиної європейської патентної системи. Визначено необхідність впровадження в Українське законодавство спеціального Кодексу законів про інтелектуальну власність, який би дозволив гармонізувати національне законодавство України у сфері ІВ до Директив та законів ЄС.
ДОСЛІДЖЕННЯ ТЕРМІЧНИХ І ТРИБОЛОГІЧНИХ ВЛАСТИВОСТЕЙ ВУГЛЕПЛАСТИКА НА ОСНОВІ ФЕНІЛОНУ С-2
Authors: Чигвінцева О.П. , Рула І.В. , Бойко Ю.В. 
Published: February 2024

Досліджені основні термічні і трибологічні властивості вуглепластика на основі ароматичного поліаміду фенілон С-2, армованого метал-вмісним вуглецевим волокном. Показано, що армування поліамідного в’яжучого хром-вмісним вуглецевим волокном у кількості 17 мас. % підвищує його термостійкість, знижує коефіцієнт тертя та збільшує зносостійкість і критерій працездатності матеріалу.
ВПЛИВ ІМПУЛЬСНОГО ОБРОБЛЕННЯ ВИСОКОВОЛЬТНИМИ ЕЛЕКТРИЧНИМИ РОЗРЯДАМИ ТА ФЛОТАЦІЙНОГО РОЗДІЛЕННЯ НА ФІЗИКО-МЕХАНІЧНІ ТА МОРФОМЕТРИЧНІ ХАРАКТЕРИСТИКИ ПОРОШКІВ СИНТЕТИЧНОГО АЛМАЗУ МАРКИ АС20 ЗЕРНИСТОСТІ 100/80
Authors: Олійник Н.О. , Ільницька Г.Д. , Петасюк Г.А. , Сизоненко О.М. , Базалій Г.А. , Заболотний С.Д. 
Published: February 2024

Дослідженнями порошку синтетичного алмазу марки АС20 зернистості 100/80 експериментально показано, що застосування оброблення високовольтними електричними розрядами при виготовлені порошків дозволяє отримувати порошки більш однорідні за морфометричними характеристиками, порошки з більшою кількістю різальних кромок та більшим кутом їх загострення, що забезпечує більш високу абразивну здатність. Застосування флотаційного розділення алмазного порошку дозволяє отримати порошок алмазу, що характеризується підвищеним показником міцності при статичному стиску на 23,8%, збільшеною однорідністю за міцністю на 25,0%, суттєво зниженою кількістю включень. Результати виконаних досліджень дають підставу стверджувати, що застосування оброблення порошку високовольтними електричними розрядами і застосування флотаційного розділення є дієвими технічними засобами впливу на морфометричні, фізико-механічні характеристики та технологічні властивості порошків синтетичного алмазу. Застосування цих двох методів відкриває можливість здійснювати вибірковий вплив на якість отримуваних порошків.
Short-term transfer effects of Tetris on mental rotation: Review and registered report — A Bayesian approach
Authors: Timm J. David , Huff Markus , Schwan Stephan , Papenmeier Frank 
Published: February 2024

AbstractThe existence of transfer effects of video games on cognitive performance are controversially discussed in experimental psychology. Whereas recent meta-analyses suggest the absence of far transfer effects, empirical evidence regarding near transfer effects is more controversial. This conceptual replication investigated the short-term near transfer effect of playing Tetris on mental rotation abilities. The design of the conceptual replication was based on a comprehensive compilation of the methods used by previous literature on this topic and advanced in order to reach a high scientific state-of-the-art standard. We ran a high-powered conceptual replication study with 366 participants randomly assigned to either an experimental group playing Tetris or a control group playing Solitaire. Both groups completed three commonly used mental rotation tests in a pre- and a posttest session. Additionally, the experimental group played Tetris while the control group played Solitaire. Playing time was 10 hours in total within 4 weeks. Based on previous research, we hypothesized that this might generate a short-term transfer effect of Tetris on mental rotation. While participants showed a repeated testing effect for the mental rotation tests in both groups, we found evidence that Tetris does not produce a short-term transfer effect on mental rotation. Both gender and expected outcomes did not influence this effect. Our study suggests that playing Tetris does not improve mental rotation skills.
Rancang Bangun Alat Ukur Pasang Surut Sensor Pressure dengan Metode Pengiriman Data Global System for Mobile Communication (GSM)
Authors: Susanto Tri , Kurniawan Endro Sigit , Negara Adhi Kusuma , Carudin Carudin 
Published: February 2024

Pasang surut merupakan perubahan tinggi permukaan air yang diakibatkan adanya fenomena gaya gravitasi bulan, oleh karena itu data ini sangat dibutuhkan dalam berbagai bidang, diantarannya bidang hidrografi, oseanografi, proyek rekayasa, perikanan. Hal ini menimbulkan konsekuensi atas ketersediaan alat ukur pasang surut dalam skala besar, praktis, ekonomis, akurat dan akses data yang cepat. Dalam penelitian ini penulis bermaksud untuk meningkatkan kemampuan prototype alat ukur pasang surut sensor pressure yang telah dikembangkan oleh peneliti sebelumnya sehingga dapat memenuhi kebutuhan tersebut serta diharapkan mampu mewujudkan kemandirian teknologi dalam negeri. Upgrade tersebut dilaksanakan dengan menggunakan microcontroller Arduino uno, sensor pressure, serta menambahan perangkat telemetri menggunakan modul GSM. Modul GSM SIM 800L merupakan jenis modul GSM/GPRS Serial yang banyak digunakan di bidang elektronika sebagai aplikasi pengendalian jarak jauh via Handphone. Hasil penelitian ini berupa prototype alat monitoring ketinggian air yang mampu memberikan informasi ketinggian air secara cepat akurat dan efisien dengan tingkat kesamaan sebesar 0.999 terhadap peralatan pabrikan Tide Master.

Kata kunci: Upgrade Prototype, Alat Ukur Pasut Pressure, Telemetri, GSM SIM 800L