bluuebunny/crossref_metadata_2025_split huggingface dataset:
Anxiety and sleep disorders in depressed patients are affected by resting state EEG rhythm
Authors: Xiong Xin , zhang jiancong , He Jianfeng , Wang Chunwu , Liu Ruixiang , Wang Aikun , Sun Zhiran , Zhang Jing 
Published: November 2023

Abstract
Background
Depression is a complex mental disease whose typical symptoms include sleep disturbances and anxiety, which often co-occur, further aggravating the patient's condition. The study aimed to investigate the relationship between EEG rhythms and sleep disorders and anxiety conditions in depressed patients, as well as physiologic indicators that may contribute to these changes.
Methods
Resting-state EEG data from 24 depressed patients and 24 healthy subjects were used to analyze EEG signal power in different frequency bands. Explored the relationship between EEG frequency bands and anxiety symptoms (assessed using the GAD-7 scale) and sleep quality (using the Pittsburgh Sleep Quality Index Scale, PQSI) through multiple regression analysis. Using the sLORETA technique, EEG source analysis was conducted to compare current densities in different brain regions between depressed patients and healthy controls.
Results
Compared with the HC group, there were significant differences in localized electrode power in major depressive disorders (MDD), focusing on electrodes in temporal, frontal, and occipital regions. Regression analysis showed that symptoms of GAD(GAD-7 score) were affected by the Beta band power, while sleep quality (PQSI score) was affected by the Alpha band power. Source localization analysis revealed that there were greater differences in current density in temporal lobe (STG, ITG, FG) and frontal lobe (IFG) in the MDD group, compared to the HC group.
Conclusion
The findings suggest that there is a close correlation between sleep disorders and Alpha band power in depressed patients, potentially indicating functional abnormalities in the left temporal lobe region as well as left lateralized asymmetrically of the Alpha band. In addition, abnormal functioning of the inferior temporal gyrus (IFG) and the fusiform gyrus (FG) in depressed patients may lead to symptoms of anxiety. The difference in current density in the temporal and frontal lobes reflects the abnormal brain activity in these regions in depressed patients and is a significant physiological marker of depression. Significance: These discoveries contribute to an in-depth understanding of the characteristics of EEG activity in patients with depression and provide new research directions for future treatment and intervention.
Percutaneous vertebroplasty for thoracolumbar osteoporotic vertebral compression fracture in patients with distant lumbosacral pain
Authors: XIAO Shanwen , ZHOU Shufang , PAN Shixin , LI Guodong , LI Aihui 
Published: November 2023

Abstract
Objective A few patients with thoracolumbar OVCF only report pain in the lumbosacral region, which was far from the level of the fractured vertebra. The study aimed to assess the therapeutic efficacy of percutaneous vertebroplasty (PVP) in patients with thoracolumbar OVCF who presented with distal lumbosacral pain (DLP), as well as investigate the potential underlying mechanisms of DLP.
Methods Sixty-nine thoracolumbar OVCF patients who exclusively reported pain in the lumbosacral region of the lower back or buttock were enrolled in the LS group. In a 1:2 ratio, 138 patients who exclusively reported thoracolumbar pain localized at the level of the fractured vertebra were selected for the control group (TL group). Clinical outcomes were evaluated utilizing the Visual Analog Scale (VAS) and Chinese modified Oswestry Disability Index (CMODI) scores. Radiographic assessment included measurements of vertebral height and Cobb angle.
Results The VAS and CMODI scores, Cobb angle, and anterior and middle vertebral heights demonstrated significant improvement following surgery in both groups (P<0.05). No significant differences were observed between the two groups in terms of postoperative CMODI scores, Cobb angle, and anterior and middle vertebral heights (P>0.05). However, the LS group exhibited lower preoperative anterior and middle vertebral heights compared to the TL group (P=0.039 and 0.043, respectively). Additionally, there were higher VAS scores at 2 days and 1 month post-operation (both P<0.0001).
Conclusion Percutaneous vertebroplasty can alleviate pain in the distal lumbosacral area caused by thoracolumbar OVCF. Excessive reduction in vertebral height may pose a potential risk for the emergence of lumbosacral pain. Patients with lumbosacral pain experienced a relatively inferior short-term pain relief following surgery compared to those with thoracolumbar pain.
Experimental and Numerical Investigation on the Behavior of Reinforced Concrete Walls Stregthened by Steel Memebers
Authors: Edlebi Ghida Edlebi , Masri Adnan Masri , Baalbaki Oussama Baalbaki , Wehbi Nour Wehbi 
Published: November 2023

Abstract
Reinforced concrete (RC) walls are commonly used in various structural applications due to their ability to withstand lateral loads and provide increased resilience. This study primarily focuses on understanding the bending characteristics and lateral resistance of RC walls, with a specific emphasis on investigating a standard section compared to its enhancement through the incorporation of steel members. The research aims to examine the stiffness, load-carrying capacity, displacement, and failure mode of RC walls through practical experiments and subsequent numerical validation using ABAQUS software. The analysis involves a scaled specimen, which, after reaching the point of failure, underwent a strengthening strategy. This approach involved attaching a diagonal steel plates to the upper part of the wall and steel members to the lower portion, referred to as the second specimen. The investigation explores how strengthening the wall with steel members affects both its resilience and failure mode. Notably, the ABAQUS model effectively simulates the lateral response of the analyzed specimens, with slight variations from the experimental results that fall within an acceptable range. Then, the effect of steel plate thickness on the behavior of the studied strengthened specimen was conducted numerically. The incorporation of steel members on both the upper and lower parts of the wall has successfully prevented sudden failure, reduced cracking, increased load-carrying capacity, and enhanced stiffness and ductility. Based on the presented results, this strengthening technique can be considered a practical retrofitting method that offers rapid implementation, a significant increase in the load-bearing capacity of damaged walls, and eliminates the need for building excavation.
Ethics-testing an eating disorder recovery memoir: A pre-publication experiment
Authors: Troscianko Emily T. , Riestra-Camacho Rocío , Carney James 
Published: November 2023

Abstract

Background:
Narratives (including memoirs and novels) about eating disorders (EDs) are typically published with the intention to benefit readers, but survey evidence suggests that reading such narratives with an active ED may more often be harmful than helpful. To reduce the probability of inadvertent harm and learn more about how narrative reading and EDs interact, a pre-publication study was designed to determine whether or not a recovery memoir should be published.
Methods:
64 participants with a self-reported ED read either the experimental text (The Hungry Anorexic [HA]) or a control text (Ten Zen Questions [TZ]) over a roughly two-week period. All participants completed the Eating Disorder Examination Questionnaire (EDE-Q) and the Anorexia Nervosa Stages of Change Questionnaire (ANSOCQ) one week before and two weeks after reading, and answered three recurring open-ended questions at six timepoints during/after the reading. Computational analysis of the free-text responses assessed text/response similarity and response characteristics on emotional, sensory, and action-effector dimensions. Both rating-scale and free-text data were analysed using mixed ANOVAs to test for effects of time and condition, and the university ethics board was notified in advance of the quantitative threshold for harmful effects that would prohibit the ED memoir from being published.
Results:
On the two quantitative measures, there was an effect of time but not of condition: Significant improvement was found in both groups on the EDE-Q (with a medium-to-large effect size) and the ANSOCQ (with a very large effect size). In an ANCOVA analysis, no significant mediating effects were found for age, education, duration of professional support for the ED, or pre/post-reading BMI change. For the free-text responses, linguistic similarity measures indicated that HA responses most closely matched the text of HA, with the same being true for TZ. In a word-norm analysis, text condition significantly affected six emotional, sensory, and action-effector variables (interoception, olfaction, gustatory, mouth, torso, and hand/arm), mean scores for all of which were higher in HA responses than TZ responses. Close reading identified five major themes in readers’ responses.
Conclusions:
The ED memoir was found not to yield measurably harmful effects for readers with an ED, and will therefore be published. The finding that significant improvement on both quantitative measures was observed irrespective of text condition suggests that positive effects may be attributable to linguistic characteristics shared by the two texts and/or to elements of the reading and or reflective processes scaffolded by both. The quantitative results and the free-text testimony have implications for our understanding of bibliotherapy, “triggering”, and the practicalities of responsible publishing.
Stress Hyperglycemia Ratio Predicts Neurological Deterioration during Stroke Patient Hospitalization
Authors: Utomo Yudhanto , Prodjohardjono Astuti , Gofir Abdul 
Published: November 2023

Abstract
Background: Clinical parameters have been largely studied as a prognostic biomarker for stroke patients. Stress hyperglycemia ratio (SHR) is one of potential and affordable biomarkers to predict acute ischemic stroke outcome. Its ability to predict neurological deterioration in acute ischemic stroke remain demonstrates variable results in previous studies particularly in diabetic group. This research aims to study the association between SHR and neurological deterioration in ischemic stroke patient during hospitalization, especially in Indonesia population.
Methods: This is a retrospective cohort utilizing in-patient data from Stoke Unit Registry of Sardjito General Hospital from January 2020 until December 2022 to obtain first-ever ischemic stroke. The researchers applied inclusion and exclusion criteria for the subjects. Stress hyperglycemia ratio represents ratio between random blood glucose at admission and estimated mean glucose. Neurological deterioration is at discharge and admission difference of NIHSS (National Institutes of Health Stroke Scale) or Delta NIHSS.
Results: Of the 207 subjects who met criteria, there was 15.5% incidence of neurological deterioration during acute care (mean 5 days). Most subjects (85%) had mild and moderate NIHSS (score 0-15), and ASPECT score >7 (78.3%). The DM group was 32.9%. Hyperglycemia and increased SHR were more prevalent in the DM group. SHR with a cut-off of 1,147 was associated with neurological deterioration with a sensitivity of 50% and specificity of 71.4% (OR=2.14, p=0.017). Hyperglycemia, DM, HbA1c, and baseline NIHSS had no significant association with neurological deterioration (p>0,05). On subgroup analysis, SHR with the same cut-off had a significant association (p<0.009, OR=3.77) only in the non-DM group. Other variables associated with neurological worsening were dyslipidemia (OR=0.414, p=0.042) and sepsis (OR=4.827, p=0.031).
Conclusion: SHR predicts neurological deterioration in the first-ever acute ischemic stroke population. In subgroup analysis SHR is significantly associated with neurological deterioration in non-DM group only.
An equine iPSC-based phenotypic screening platform identifies pro- and anti-viral molecules against West Nile virus
Authors: Cochet Marielle , Piumi François , Gorna Kamila , Berry Noémie , Gonzalez Gaëlle , Danckaert Anne , Aulner Nathalie , Blanchet Odile , Zientara Stéphan , Donadeu Francesc Xavier , Munier-Lehmann Hélène , Richardson Jennifer , Benchoua Alexandra , Coulpier Muriel 
Published: November 2023

Abstract
Outbreaks of West Nile virus (WNV) occur periodically, affecting both human and equine populations. There are no vaccines for humans, and those commercialised for horses do not have sufficient coverage. Specific antiviral treatments do not exist. Many drug discovery studies have been conducted, but since rodent or primate cell lines are normally used, results cannot always be transposed to horses. There is thus a need to develop relevant equine cellular models. Here, we used induced pluripotent stem cells to develop a new in vitro model of WNV-infected equine brain cells suitable for microplate assay, and assessed the cytotoxicity and antiviral activity of forty-one chemical compounds. We found that one nucleoside analog, 2’C-methylcytidine, blocked WNV infection in equine brain cells, whereas other compounds were either toxic or ineffective, despite some displaying anti-viral activity in human cell lines. We also revealed an unexpected proviral effect of statins in WNV-infected equine brain cells. Our results thus identify a potential lead for future drug development and underscore the importance of using a tissue and species relevant cellular model for assessing the activity of antiviral compounds.
Comparison Analysis of Short-Term Efficacy between High Tibial Osteotomy Combined with Medial Meniscus Posterior Root Repair or Partial Resection
Authors: Ren Fuji , Wu Jiang , Zhao Dong , Wang Rui , huang jingmin 
Published: November 2023

Abstract
Objective Comparative analysis of the clinical efficacy of high tibial osteotomy combined with medial meniscus posterior root repair or partial meniscectomy in the treatment of medial compartment osteoarthritis with concomitant knee varus. Methods Based on the inclusion and exclusion criteria, a retrospective analysis of clinical data was conducted on 42 patients who underwent medial open-wedge high tibial osteotomy in our department from January 2020 to January 2021. Group 1 consisted of 20 patients who underwent high tibial osteotomy combined with medial meniscus posterior root repair, while Group 2 consisted of 22 patients who underwent high tibial osteotomy combined with partial meniscectomy of the medial meniscus posterior root. Clinical and radiological evaluations were performed, comparing preoperative and postoperative 2-year VAS scores, IKDC scores, WOMAC scores, as well as KL grading, WBL, HKA, degree of medial meniscal extrusion, and width of medial joint space. The correlations between these parameters were analyzed. Furthermore, arthroscopic examination was performed at the 2-year follow-up to evaluate the healing condition of the medial meniscus posterior root and changes in the cartilage of the medial femoral condyle (MFC) and medial tibial plateau (MTC).
Results All patients showed significant improvements in VAS scores, IKDC scores, WOMAC scores, and medial joint space width, with statistically significant differences before and after surgery. However, there was no statistically significant difference in the degree of medial meniscal extrusion between the two groups before and after surgery. The healing rate of the medial meniscal root was higher in Group 1 (75%) than in Group 2 (54.5%). In terms of postoperative VAS, IKDC, WOMAC scores, postoperative medial joint space width, healing rate of the medial meniscal root, and medial compartment cartilage regeneration, Group 1 performed significantly better than Group 2. There was a significant negative correlation between changes in medial joint space width and changes in medial meniscal extrusion. No correlation was observed between other observed indicators and changes in medial meniscal extrusion.
Conclusions In patients with medial compartment osteoarthritis combined with medial meniscal root tear, the clinical efficacy of opening-wedge high tibial osteotomy combined with medial meniscal root repair is significantly better than OWHTO combined with partial meniscectomy of the medial meniscal root.
Joining of AA5052 to CF/PEEK by friction lap welding
Authors: Sheikh-Ahmad Jamal , Zitoune Redouane , Morel Claire , Ferrero Jean-François , Vieille Benoit 
Published: November 2023

Abstract
The joining of aluminum alloy AA5052 and carbon fiber reinforced polyether ether ketone (CF/PEEK) by friction lap welding was investigated under different conditions of surface texturing and process temperatures. The joint quality was evaluated by measurement of the tensile shear force and examination of the joint morphology. The welding experiments were conducted under different tool rotational speeds for two types of surface texturing of the aluminum alloy, namely mechanical engraving and sand blasting. The temperatures across the weld line were measured during the process of welding using thermocouples mounted at specific locations, and the temperature distribution at the interface was determined by an inverse heat conduction method. It was found that the temperatures at the interface exceeded the melting temperature of PEEK for all testing conditions, but was always below PEEK thermal degradation temperature. It was also found that joint performance of mechanically engraved samples increased with increasing the interface temperatures. This was attributed to the increased mechanical interlocking due to the flow of melted PEEK into surface features of the engraved sample. The joint strength of sand blasted samples did not change considerably with interface temperatures.
Geographical accessibility of medical resources, health status, and demand of integrated care for the elderly: a cross-sectional survey from Western China
Authors: Lin Taoyu , Guo Wei , Li Yuanyuan , Guo Xiaoying , Bai Xue , Min Rui 
Published: November 2023

Abstract
Background
WHO calls for the Integrated Care for Older People (ICOPE) system to cope with the population aging crisis. However, the relevant evidence on the demands of older people and the compensatory capacity of the environment is limited. This study aims to clarify the ICOPE demands in Western China and analyze the impact of geographic accessibility of medical resources (GAMR) on ICOPE demands and the potential mechanism of health status.
Methods
A cross-sectional questionnaire survey was conducted among 1200 people aged 60 years and above selected through multi-stage stratified cluster sampling to obtain relevant data, including ICOPE demands, health status, and GAMR. Propensity score matching was used to analyze the impact of GAMR on ICOPE demand. The Sobel mediation test with a bootstrapping process was used to analyze the mediating effect of self-rated health status on the impact of chronic disease on ICOPE demand in different GAMR groups.
Results
Of the total participants, 1043 were eligible for the study. The mean score of ICOPE demands among all participants was 3.68 (SD = 0.78). After adjusting for covariates between high and low GAMR groups (1:1 match), ICOPE demand was significantly higher in the low GAMR group than in the high GAMR group (ATT = 0.270, p < 0.05). For both good and poor self-rated health status, the ICOPE demand of the low GAMR group was significantly higher than that in the high GAMR group (ATT = 0.345,p < 0.05; ATT = 0.190, p < 0.05). For chronic diseases, the ICOPE demand of elderly with multimorbidity in the low GAMR group was significantly higher than that in the high GAMR group (ATT = 0.318, p < 0.01). In the low GAMR group, multimorbidity directly affected ICOPE demand independent of self-rated health (β = 0.342, p < 0.001) and indirectly affected ICOPE demand through self-rated health (β = 0.036, p < 0.05).
Conclusion
The elderly population in Western China has a high demand for ICOPE. Low GAMR is a key factor in ICOPE demand growth in this region. It accelerates demand release for both the elderly with multimorbidity and self-perceptions of healthy and unhealthy, opens the mediation path of the subjective health status between the complications and ICOPE demand, and increases the ICOPE demand gap.
Engaging underrepresented groups in community physical activity initiatives: A qualitative case study of parkrun in the UK
Authors: Quirk Helen 
Published: November 2023

Abstract
Background
Underrepresented groups, including racial/ethnic minority groups, individuals with low socioeconomic status, and individuals with long-term health conditions face complex barriers to engaging in community-based health initiatives. This research uses parkrun as a case study to explore the engagement strategies that have been used to promote the inclusivity and diversity of parkrun events.
Methods
Ten adult parkrun volunteers who fulfilled roles that involved promoting parkrun to underrepresented groups in the UK were interviewed. Interviews took place via telephone or video call in April-July 2021. Interview transcripts were analysed thematically.
Results
The approaches to engaging with underrepresented groups varied from opportunistic promotion within communities to strategic negotiations at higher decision-making levels. Approaches were characterised by a community-centred focus that ensured community networks and assets were utilised when promoting parkrun. A common challenge to outreach for Ambassadors was limited personal and organisational capacity that impeded the widescale scope and reach of parkrun’s engagement attempts.
Conclusions
Parkrun Ambassadors have used a wide range of approaches to outreach at different levels of influence. A number of challenges to doing meaningful and effective outreach need to be addressed. Working with and alongside communities where parkrun events take place to understand how to address inclusivity issues could contribute to greater participation in parkrun by underserved groups.
Biased news sharing and partisan polarization on social media
Authors: Pozo Sofía M del , Pinto Sebastián , Serafino Matteo , García Lucio , Makse Hernán A. , Balenzuela Pablo 
Published: November 2023

Abstract
In the ever-connected digital landscape, news dissemination on social media platforms serves as a vital source of information for the public. However, this flow of information is far from unbiased. It is deeply influenced by the political inclinations of the users who share news as well as the inherent biases present in the news outlets themselves. These biases in news consumption play a significant role in the creation of echo chambers and the reinforcement of beliefs. This phenomenon, in turn, influences the voting intentions of the population during critical electoral periods. In this study, we use a metric called ''Sentiment Bias”, a tool designed to classify news outlets according to their biases. We explore the impact of this metric on various levels, ranging from news outlets to individual user biases. Our metric, while simple, unveils a well-known trend: users prefer news aligning with their political beliefs. Its power lies in extending this insight to specific topics. Users consistently share articles related to subjects that echo their favored candidates, illuminating a deeper layer of political alignment in online discourse.