bluuebunny/crossref_metadata_2025_split huggingface dataset:
Results of long‐term follow‐up after curative resection of Dukes a colorectal cancer
Authors: Wichmann Matthias W. , Müller Christian , Hornung Hans M. , Lau‐Werner Ulla , Schildberg Friedrich‐Wilhelm ,   the Colorectal Cancer Study Group
Published: October 2002

AbstractPatients with Dukes A (UICC I) colorectal cancer have a good prognosis after curative resection. It is not known, however, if the outcome is significantly different for UICC la and lb patients or if patients with reduced risks of recurrences can be identified early after surgery. This is of interest, as it would permit a more cost‐effective, patient‐oriented, and tumor stage‐oriented follow‐up program. To study these questions, a prospective follow‐up database, including 1375 patients after curative resection of colorectal cancer, was analyzed. A total of 296 patients with Dukes A colorectal cancer with a median follow‐up of 44 months were studied. Perioperative and follow‐up mortality rates were 3% and 14%, respectively. Recurrent disease developed in 10% of Dukes A patients after a disease‐free interval of 16 months. Significantly more patients suffering from pT2 (UICC Ib) cancer had recurrent disease than patients with pT1 (UICC Ia) cancer (13% vs. 4%; p<0.05). Preoperative CEA levels in patients with recurrent disease were significantly higher than in long‐term disease‐free patients (5.3±1.8 vs. 3.5±0.6 ng/ml; p<0.05). Curative resection of recurrent disease was achieved in 38% of the patients with recurrences (4% of all patients). Survival analysis showed significantly better survival in patients with Dukes A cancer than in those at higher tumor stages (log rank,<0.0001), and only 39% of all Dukes A patients who died during follow‐up had recurrent disease. Dukes A (UICC Ia and Ib) colorectal cancer was diagnosed in 22% of our patients treated for cure, and long‐term survival was 86%. There were significantly fewer cases of recurrent disease after curative resection of UICC Ia (pT1N0M0) cancer, so we propose a novel, less intensive follow‐up regimen for these patients, leading to a more cost‐effective, patient‐oriented, and tumor stage‐oriented follow‐up program.
Acidihalobacter
Authors: Khaleque Himel N. , Vergara Eva , Holmes David , Watkin Elizabeth 
Published: January 2024

Abstract

A.ci.di.ha.lo.bac'ter. L. neut. adj.
acidum
, an acid; from L. masc. adj.
acidus
, sour; Gr. masc. n.
hals
, sea, salt; N.L. masc. n.
bacter
, rod; N.L. masc. n.
Acidihalobacter
, an acid‐loving, salt‐loving rod.

Pseudomonadota / Gammaproteobacteria / Chromatiales / Ectothiorhodospiraceae / Acidihalobacter

The genus
Acidihalobacter
comprises acidophilic, halotolerant, and chemolithoautotrophic bacteria that are able to oxidize ferrous iron and sulfur sources. Cells of these species are Gram‐stain‐negative, aerobic, and motile rods that can appear curved when under salt stress. Cells possess a single polar flagellum and can contain ferric granules. All members of the genus
Acidihalobacter
have been shown to grow on the sulfidic ores pyrite, chalcopyrite, and pentlandite.

Grow to greater cell densities on sulfur sources than on ferrous iron. They are generally mesophilic and require minimum 0.04 M chloride ion for growth. Some species can fix atmospheric nitrogen. The known habitats are marine sediments in hydrothermal areas and acidic saline drains.

DNA G + C content (mol%)
: 59.9–64.5.

Type species
:
Acidihalobacter prosperus
Cárdenas et al. 2015
VP
(synonym: “
Thiobacillus prosperus
” Huber and Stetter 1989.
Hansschlegelia
Authors: Agafonova Nadezhda V. , Kaparullina Elena N. , Doronina Nina V. 
Published: January 2024

Abstract

Hans.schle.ge'li.a. N.L. fem. n.
Hansschlegelia
, of Hans Schlegel, named after the famous German microbiologist, Professor Hans G. Schlegel, known for his classic studies on autotrophic bacteria.

Pseudomonadota / Alphaproteobacteria / Rhizobiales / Methylopilaceae / Hansschlegelia

The genus
Hansschlegelia
is represented by Gram‐negative, nonsporulating, colorless, and nonmotile or motile short rod‐shaped bacteria that occur singly or in pairs. Colonies are white to light pink, translucent, convex, round, and up to 2 mm in diameter. Obligate aerobes, having a strict respiratory type of metabolism with oxygen as the terminal electron acceptor. Reduce nitrates to nitrites. Restricted facultative methylotrophs. Assimilate C
1
compounds via the isocitrate lyase‐negative serine pathway. Utilize only several polycarbon substrates. Growth occurs on a mineral salt medium with methanol, formate, and glycerol; some strains can utilize methylamine. Growth factors are not required. Nitrogen sources include methylamine, amino acids, ammonium salts, and nitrates. Methyl red‐ and Voges–Proskauer‐negative. Urease‐, catalase‐, and oxidase‐positive. Able to form indole from
l
‐tryptophan on mineral medium with methanol and KNO
3
. Neutrophilic and mesophilic. Growth at pH 5.0–9.0 and within a temperature range between 10 and 40°C. No growth in the presence of 2% NaCl (w/v). The major ubiquinone is Q‐10. The dominant phospholipids are phosphatidylethanolamine, phosphatidylcholine, and diphosphatidylglycerol. The prevailing cellular fatty acids are C
18:1
ω7
c
, C
16:0
, and C
19:0
cyclo acids. The genome sizes range between 3.58 and 4.62 Mb. According to Genome Taxonomy Database (GTDB), the genus
Hansschlegelia
belongs to the phylum
Pseudomonadota
, class
Alphaproteobacteria
, order
Rhizobiales
, and family
Methylopilaceae
.

The type species is
Hansschlegelia plantiphila
. Representatives of this genus inhabit phyllosphere and rhizosphere of various plants and rhizospheric and polluted farmland soils.

DNA G + C content (mol%)
: 67.0–69.4 (genome sequence).

Type species
:
Hansschlegelia plantiphila
Ivanova et al. 2007, VL133.
Geoalkalibacter
Authors: Zavarzina Daria G. , Merkel Alexander Y. 
Published: January 2024

Abstract

Ge.o.al.ka.li.bac.ter. Gr. fem. n.
gê
, earth; Arabic article
al
, the; Arabic masc. n.
qaly
, ashes of saltwort; N.L. neut. n.
alkali
, alkali (indeclinable); N.L. masc. n.
bacter
, rod; N.L. masc. n.
Geoalkalibacter
, a rod from alkaline earth.

Desulfobacterota / Desulfuromonadia / Desulfuromonadales / Geoalkalibacteraceae / Geoalkalibacter

The genus
Geoalkalibacter
is represented by Gram‐negative non‐spore‐forming rods. Cells of most species of the genus are motile by means of laterally or polarly located flagella. Members of the genus are strictly anaerobic, alkalitolerant or obligately alkaliphilic, and halotolerant or moderately halophilic mesophiles. They grow by anaerobic respiration with Fe(III), Mn(IV), or sulfur compounds as an electron acceptor. Molecular hydrogen, organic acids, alcohols, peptides, and Fe(II)‐containing minerals can serve as electron donors. All members of the genus are electroactive microorganisms that use extracellular electron transfer (EET) to achieve respiratory processes with insoluble electron acceptors. Some of these bacteria are capable of atmospheric nitrogen fixation. The known habitats are haloalkaline soda lakes and subsurface oil reservoirs. The genus
Geoalkalibacter
contains two species with validly published names and belongs to the phylum
Desulfobacterota
, class
Desulfuromonadia,
order
Desulfuromonadales
, and family
Geoalkalibacteraceae
.

DNA G + C content (mol%)
: 57.05–60.57 (genome analysis).

Type species
:
Geoalkalibacter ferrihydriticus
Zavarzina et al. 2006, VL115.
Aristides “the Just” (Aristeides)
Authors: Zaccarini Matteo 
Published: January 2024

Abstract
Aristides was one of the leading Athenian politicians between the Persian wars and the early years of the naval alliance. He is mostly known from the tradition as “the Just” due to his reputation for honesty and integrity, but this – disputed – fame seems to have been developed and settled long after his lifetime. Therefore, Aristides remains an archetypical and yet obscure symbol of Athenian imperialism.
Lygdamis of Halikarnassos
Authors: Fabiani Roberta 
Published: January 2024

AbstractLygdamis of Halikarnassos, grandson of Artemisia, was tyrant of Halikarnassos around the middle of the fifth centurybce. He is known from the biographical tradition on Herodotus and from a law inscribed on stone. He exercised a formally recognized authority along with the city institutions; his power was thus to a certain degree institutionalised.
Academy
Authors: Spinelli Emidio 
Published: January 2024

Abstract
The Platonic Academy, founded with the aim of providing training in politics, took the form of a community of researchers in philosophical, scientific, and ethical fields. This inclination toward philosophical discussion is reflected by the different interpretations of the founder's doctrine developed over the centuries: while with Speusippos and Xenokrates there was a mathematizing philosophy, with Arcesilaus’ skeptical turn a phase began based on the importance of suspending judgment. An effort to return to dogmatism was made by Antiochos by integrating Peripatetic and Stoic positions into the Old‐Academic doctrinal core. The Academy ended as an institution with the sack of Athens.
Harim
Authors: Manley Bill 
Published: January 2024

Abstract
Harim (harem) is the modern word conventionally used to translate several Ancient Egyptian terms associated with the royal family or to describe buildings apparently used by royal women. This is far from satisfactory: partly because the words are not obviously synonyms; partly because they do not correspond straightforwardly to specific buildings; and partly because the word “harim” brings unjustifiable connotations about the status and activities of women within the royal palace community, which in some instances were organised on an industrial basis.
Aeternitas
Authors: Dowling Melissa Barden 
Published: January 2024

Abstract

Aeternitas
, “Eternal Time,” appeared in Roman Republican literature and increased in popularity through Late Antiquity. In an age of intense interest in astrology, cosmology, and temporality,
Aeternitas
embodied changeless, endless, indivisible eternity, in contrast to other ancient conceptions of cyclical, divisible time. The personification of
Aeternitas
appeared as a draped woman holding the sun and the moon or a phoenix perched on a globe (alluding to the rebirth of an endless golden age). In the third century
ce
, winged male figures representing cosmic eternity appeared and the imagery of
Aeternitas
merged with that of Helios, Sol, and Aion.
Harpokrates
Authors: Dowling Melissa Barden 
Published: January 2024

Abstract
Harpokrates was the Greek name for Horus the Child, son of Isis and Osiris, the manifestation of the sun at dawn, an integral part of the cycle of Osiris’ death and rebirth as Horus. He appeared as a baby nursing at Isis’ breast, as a chubby boy with a finger pressed to his lips to signal silence, or as a crowned youth. Harpokrates was often depicted standing on a crocodile or hippopotamus (Seth) or curled on a lotus. Enormous numbers of coins, gems, lamps, and votives representing Harpokrates exist across the ancient world.
Sarapis
Authors: Dowling Melissa Barden 
Published: January 2024

Abstract

Sarapis (Serapis in Latin), a god of creation, eternal life, secret knowledge, and healing, combined the cults of Osiris and Apis (Oserapis). The new cult emerged during the Egyptian Late Period and, with the cults of his wife Isis, son Horus, and other Egyptian gods, spread across the Greco‐Roman world. Sarapis was assimilated with Dionysos, Zeus, Helios, and Asklepios, and usually was represented in Greek form as a bearded man wearing a
kalanthos
, seated on a throne, and accompanied by Cerberus. Ancient literature, inscriptions, offerings, and sanctuaries in Saqqara, Alexandria, Rome, Delos, and Carthage, provide evidence for the cult.
Supramolecular Aza Crown Ether Modulator for Efficient and Stable Perovskite Solar Cells
Authors: Chen Xia , Deng Chunyan , Wu Jihuai , Chen Qi , Du Yitian , Xu Yuan , Li Ruoshui , Tan Lina , Wei Yuelin , Huang Yunfang , Lan Zhang 
Published: January 2024

AbstractMolecular modulators have been demonstrated to be an effectual strategy for reducing the defect at the interface and in bulk of perovskite and ameliorating the performance and stability of perovskite solar cells (PSCs). Herein, 1‐aza‐15‐crown 5‐ether (A15C5), with a unique nitrogen heterocyclic structure as a molecular modulator is introduced at the interface between perovskite layer and hole transport layer of PSCs. Multiple supramolecular synergistic interaction between A15C5 and perovskite dramatically suppress and passivate defects, resulting in a 38% decrease in electron trap‐state density in perovskite. The formation of two‐dimensional/th3D perovskite heterojunctions induced by planar A15C5 releases residual strain of perovskite film, optimizes the match of energy level array and boosts the stability of devices. Consequently, A15C5‐modulated PSC achieves an impressing efficiency of 24.13% along with excellent humidity, light and thermal stability. This work provides a typical strategy to utilize supramolecular crown ether in PSCs.
Thermo‐Responsive Trilayered Fibrous Dressing with Liquid Gate for Dynamical Exudate Regulation and Wound Moisture Balance
Authors: Qiu Zhiye , Gao Yujie , Qi Dongming , Wu Minghua , Mao Zhengwei , Wu Jindan 
Published: January 2024

AbstractExudate plays a crucial role in wound healing, but an excessive amount can lead to over‐hydration of tissue and aggravating the infection and the injury. On the other hand, inadequate exudate can cause scarring and hinder healing. Traditional wound dressings are unable to regulate exudate levels based on the specific needs of the wound. To address this issue, a liquid‐gated trilayered fibrous wound dressing capable of pumping fluid in a temperature‐dependent manner is developed. This dressing comprises a hydrophilic cotton layer, a thermo‐sensitive (TPPU) layer, and a hydrophobic layer of polyurethane (PU) nanofibers. The TPPU layer is constituted by nanofibers that are composed of an upper critical solution temperature (UCST)‐type polymer, PU, and silver nanoparticles. The intermediate TPPU layer exhibits changes in its wettability upon heating, adjusting the thickness of the hydrophobic layer and ultimately achieving the appropriate structure for guiding spontaneous fluid transport. The positive effect of this novel dressing on diabetic wounds is observed, as it enhanced epithelialization and collagen synthesis while reducing inflammation, ultimately accelerating the wound healing process. This dressing has the potential to provide a groundbreaking solution for managing exudate, achieving moisture balance and promoting wound healing in clinical settings.
Amplified and Specific Staining of Protein Dimerization on Cell Membrane Catalyzed by Responsively Installed DNA Nanomachines for Cancer Diagnosis
Authors: Wang Zhenqiang , Xie Xiyue , Jin Kaifei , Xia Daqing , Zhu Jing , Zhang Jixi 
Published: January 2024

AbstractIn situ staining of protein dimerization on cell membrane has an important significance in accurate diagnosis during perioperative period, yet facile integration of specific recognition function and local signal conversion/amplification abilities on membrane surface remains a great challenge. Herein, a two‐stage catalytic strategy is developed by installing DNA nanomachines and employing. Specifically, dual‐aptamer‐assisted DNA scaffold perform a “bispecific recognition‐then‐computing” operation and the output signal initiate a membrane‐anchored biocatalysis for self‐assembly of DNA catalytic converters, that is, G‐quadruplex nanowire/hemin DNAzyme. Then, localized‐deposition of chromogenic polydopamine is chemically catalyzed by horseradish peroxidase‐mimicking DNAzyme and guided by supramolecular interactions between conjugate rigid plane of G‐tetrad and polydopamine oligomer. The catalytic products exhibit nanofiber morphology with a diameter of 80–120 nm and a length of 1–10 µm, and one‐to‐one localize on DNA scaffold for amplified and specific staining of protein dimers. The bispecific staining leads to a higher (≈3.4‐fold) signal intensity than traditional immunohistochemistry, which is beneficial for direct visualization. Moreover, an efficient discrimination ability of the bispecific staining strategy is observed in co‐culture model staining. This study provides a novel catalytic method for controlling deposition of chromogens and paves a new avenue to sensitively stain of protein‐protein interactions in disease diagnosis.
Redox Gating for Colossal Carrier Modulation and Unique Phase Control
Authors: Zhang Le , Liu Changjiang , Cao Hui , Erwin Andrew J. , Fong Dillon D. , Bhattacharya Anand , Yu Luping , Stan Liliana , Zou Chongwen , Tirrell Matthew V. , Zhou Hua , Chen Wei 
Published: January 2024

AbstractRedox gating, a novel approach distinct from conventional electrolyte gating, combines reversible redox functionalities with common ionic electrolyte moieties to engineer charge transport, enabling power‐efficient electronic phase control. This study achieves a colossal sheet carrier density modulation beyond 1016 cm−2, sustainable over thousands of cycles, all within the sub‐volt regime for functional oxide thin films. The key advantage of this method lies in the controlled injection of a large quantity of carriers from the electrolyte into the channel material without the deleterious effects associated with traditional electrolyte gating processes such as the production of ionic defects or intercalated species. The redox gating approach offers a simple and practical means of decoupling electrical and structural phase transitions, enabling the isostructural metal‐insulator transition and improved device endurance. The versatility of redox gating extends across multiple materials, irrespective of their crystallinity, crystallographic orientation, or carrier type (n‐ or p‐type). This inclusivity encompasses functional heterostructures and low‐dimensional quantum materials composed of sustainable elements, highlighting the broad applicability and potential of the technique in electronic devices.
3D Tiled Auxetic Metamaterial: A New Family of Mechanical Metamaterial with High Resilience and Mechanical Hysteresis
Authors: Li Tiantian , Li Yaning 
Published: January 2024

AbstractFor artificial materials, desired properties often conflict. For example, engineering materials often achieve high energy dissipation by sacrificing resilience and vice versa, or desired auxeticity by losing their isotropy, which limits their performance and applications. To solve these conflicts, a strategy is proposed to create novel mechanical metamaterial via 3D space filling tiles with engaging key‐channel pairs, exemplified via auxetic 3D keyed‐octahedron–cuboctahedron metamaterials. This metamaterial shows high resilience while achieving large mechanical hysteresis synergistically under large compressive strain. Especially, this metamaterial exhibits ideal isotropy approaching the theoretical limit of isotropic Poisson's ratio, ‐1, as rarely seen in existing 3D mechanical metamaterials. In addition, the new class of metamaterials provides wide tunability on mechanical properties and behaviors, including an unusual coupled auxeticity and twisting behavior under normal compression. The designing methodology is illustrated by the integral of numerical modeling, theoretical analysis, and experimental characterization. The new mechanical metamaterials have broad applications in actuators and dampers, soft robotics, biomedical materials, and engineering materials/systems for energy dissipation.
A Tough Monolithic‐Integrated Triboelectric Bioplastic Enabled by Dynamic Covalent Chemistry
Authors: Shao Yuzheng , Du Guoli , Luo Bin , Liu Tao , Zhao Jiamin , Zhang Song , Wang Jinlong , Chi Mingchao , Cai Chenchen , Liu Yanhua , Meng Xiangjiang , Liu Zhaomeng , Wang Shuangfei , Nie Shuangxi 
Published: January 2024

AbstractElectronic waste is a growing threat to the global environment and human health, raising particular concerns. Triboelectric devices synthesized from sustainable and degradable materials are a promising electronic alternative, but the mechanical mismatch at the interface between the polymer substrate and the electrodes remains unresolved in practical applications. This study uses the sulfhydryl silanization reaction and the chemical selectivity and site specificity of the thiol–disulfide exchange reaction in dynamic covalent chemistry to prepare a tough monolithic‐integrated triboelectric bioplastic. The stress is dissipated by covalent bond adaptation to the interface interaction, which makes the polymer dielectric layer to the conductive layer have a good interface adhesion effect (220.55 kPa). The interfacial interlocking of the polymer substrate with the conductive layer gives the triboelectric bioplastic excellent tensile strength (87.4 MPa) and fracture toughness (33.3 MJ m−3). Even when subjected to a tension force of 10 000 times its weight, it still maintains a stable triboelectric output with no visible cracks. This study provides new insights into the design of reliable and environmentally friendly self‐powered devices, which is significant for the development of flexible wearable electronics.
Perovskite‐Derived Layered Crystal Structure in SrCo0.26Fe0.74O3‐δ Thin Films
Authors: Cho Eunsoo , Kumar Abinash , Ning Shuai , LeBeau James M. , Ross Caroline A. 
Published: January 2024

AbstractOxygen coordination and vacancy ordering play an important role in dictating the functionality of complex oxides. In this work, an unconventional layering of oxygen ions in a mixed conductor SrCo1‐xFexO3‐δ (SCFO) thin film grown epitaxially on SrTiO3 (STO) is reported. Scanning transmission electron microscopy (STEM) reveals alternating layers of oxygen deficiency along the growth direction, with the oxygen‐rich layer correlated with the neighboring Co,Fe‐site intensity, and contraction of the Sr–Sr distance. Density functional theory (DFT) calculations and STEM image simulations support the emergence of periodic (Co,Fe)O6 and (Co,Fe)O4/(Co,Fe)O5 layers, an ordering that is also sensitive to the Co:Fe ratio.
Effect of Anthraquinone‐Substituted Graphdiyne Analog on the Growth of Lithium Dendrites
Authors: He Jingyi , Hu Guilin , Chen Jing , Li Yongjun 
Published: January 2024

AbstractEnhancing the cycling efficiency and controlling lithium dendrite growth through a stable and heterogeneous lithium‐electrolyte interface are crucial steps for the practical application of lithium metal batteries. In this study, a carbon network composed of graphdiyne modified with redox‐active anthraquinone units (AN‐GDY) is developed to optimize the performance of the battery separator (PE film) also lithium anode. The AN‐GDY films are integrated with the conventional commercial battery separator (PE film) to create a double‐separator system, aimed at enhancing the interior characteristics of the battery. Electrochemical tests confirme that lithium symmetric batteries with AN‐GDY/PE double‐separator system can deliver high areal capacities of 1, 2, and 5 mAh cm−2 and ultra‐high current densities of 1, 2, and 5 mA cm−2 stable Li plating/stripping for over 800 h. Furthermore, lithium batteries employing AN‐GDY as the lithium anode preserve a capacity of 100 mAh g−1 and exhibite a Coulombic efficiency exceeding 98% after 5000 cycles, even at a high current rate of 500 mA g−1.