bluuebunny/crossref_metadata_2025_split huggingface dataset:
Cancer mortality and competing causes of death in older adults with cancer: A prospective, multicentre cohort study (ELCAPA‐19)
Authors: Assouan Déborah , Paillaud Elena , Caillet Philippe , Broussier Amaury , Kempf Emmanuelle , Frelaut Maxime , Brain Etienne , Lorisson Emmanuelle , Chambraud Clelia , Bastuji‐Garin Sylvie , Hanon Olivier , Canouï‐Poitrine Florence , Laurent Marie , Martinez‐Tapia Claudia 
Published: November 2023

AbstractBackgroundIn older patients with cancer, comorbidities compete with cancer for cause of death. The objectives were to evaluate cancer mortality and factors associated, according to metastatic status.MethodsBetween 2007 and 2014, patients with cancer aged ≥70 referred for pre‐therapeutic geriatric assessment (GA) were included through the ELCAPA prospective cohort study. The underlying cause of death was defined according to the International Classification of Diseases, 10th Revision. The World Health Organisation definition was used to categorise the cause of death as cancer versus another disease (e.g. cardiovascular disease, infectious disease, etc.) Competing risk models were used.ResultsMean (SD) age of the 1445 included patients was 80.2 (5.8) and 48% were women. Most common tumour sites were colorectal (19%), breast (17%) and urinary (15%); 773 patients (49%) had metastases. After a 34‐month median follow‐up, 706 cancer deaths were observed among 843 deaths. The 6‐month and 3‐year cancer mortality rates (95% CI) were 12% (9–15) and 34% (29–38) for non‐metastatic patients and 43% (39–47) and 79% (75–82) for metastatic patients, respectively. Dependency in activities of daily living and comorbidities were associated with 6‐month and 3‐year cancer mortality in non‐metastatic (adjusted subhazard ratio [aSHR] = 1.68 [0.99–2.85] and 1.69 [1.16–2.45]; and 1.98 [1.08–3.63] and 3.38 [1.47–7.76], respectively) and metastatic patients (aSHR = 2.81 [2.01–3.93] and 2.95 [2.14–4.07]; and 1.63 [1.18–2.25] and 2.06 [1.39–3.05], respectively). Impaired Timed‐Get‐Up‐and‐Go test was associated with 6‐month and 3‐year cancer mortality in metastatic patients (aSHR = 1.5 [1.06–2.12] and 1.38 [1.06–1.81], respectively). Obesity was negatively associated with 3‐year cancer death in non‐metastatic (aSHR = 0.53 [0.29–0.97]) and metastatic patients (aSHR = 0.71 [0.51–1.00]).ConclusionsThe majority of older adults with cancer referred for pre‐therapeutic GA die from cancer. Geriatric parameters are independently associated with cancer mortality and should be considered for prognosis assessment, decision‐making and care.
Keeping it in the family: Use of the grandmother, mother, and child technique to navigate complex anatomy during Coronary sinus Reducer Implantation
Authors: Reddy Rohin K. , Foley Michael , Giannini Francesco , Al‐Lamee Rasha K. 
Published: November 2023

AbstractThe Coronary Sinus Reducer® (CSR) is an emerging therapy for refractory angina recommended once no further pharmacologic or coronary revascularization options are available. We present the case of a 72‐year‐old man who underwent CSR implantation. Complex coronary sinus anatomy necessitated an innovative “grandmother, mother, and child” catheter approach.
Integrating Benzoxazine‐PDMS 3D Networks with Carbon Nanotubes for flexible Pressure Sensors
Authors: Puozzo Hugo , Saiev Shamil , Bonnaud Leïla , Beljonne David , Lazzaroni Roberto 
Published: November 2023

AbstractShapeable and flexible pressure sensors with superior mechanical and electrical properties are of major interest as they can be employed in a wide range of applications. In this regard, elastomer‐based composites incorporating carbon nanomaterials in the insulating matrix embody an appealing solution for designing flexible pressure sensors with specific properties. In this study, PDMS chains of different molecular weight were successfully functionalized with benzoxazine moieties in order to thermally cure them without adding a second component, nor a catalyst or an initiator. These precursors were then blended with 1 weight percent of multi‐walled carbon nanotubes (CNTs) using an ultrasound probe, which induced a transition from a liquid‐like to a gel‐like behavior as CNTs generate an interconnected network within the matrix. After curing, the resulting nanocomposites exhibit mechanical and electrical properties making them highly promising materials for pressure‐sensing applications.
The PURPLE mystery: Semantic meaning of three purple terms in French speakers from Algeria, France, and Switzerland
Authors: Epicoco Déborah , Mohr Christine , Uusküla Mari , Quiblier Michael , Meziane Maliha Bouayed , Laurent Eric , Spagnulo Giulia F. M. , Jonauskaite Domicele 
Published: November 2023

AbstractStudies on the color category PURPLE yielded inconsistent category boundaries, focal colors, and color‐emotion associations. In French, there are at least three color terms referring to the shades of purple, potentially weighing on these inconsistencies. Thus, we tested the semantic breadth and richness in semantic meaning of violet (basic term), lilas (non‐basic), and pourpre (non‐basic). We collected free associations in 274 French speakers from Algeria, France, and Switzerland, yielding 2079 responses, of which 436 were discrete and 275 were unique. Frequency analyses and semantic coding supported the basicness status of violet in French, within a hierarchically structured semantic system. Moreover, the meaning of the three terms was not synonymous. Violet had the most abstract meaning. Lilas had the narrowest meaning, mainly referring to Natural Entities. Pourpre seemed close to RED. We found no differences between the countries. Future studies should extend this approach to other languages and other color terms.
Does depth divide? Variable genetic connectivity patterns among shallow and mesophotic Montastraea cavernosa coral populations across the Gulf of Mexico and western Caribbean
Authors: Sturm Alexis B. , Eckert Ryan J. , Carreiro Ashley M. , Klein Allison M. , Studivan Michael S. , Dodge Farelli Danielle , Simões Nuno , González‐Díaz Patricia , González Méndez Juliett , Voss Joshua D. 
Published: November 2023

AbstractDespite general declines in coral reef ecosystems in the tropical western Atlantic, some reefs, including mesophotic reefs (30–150 m), are hypothesized to function as coral refugia due to their relative isolation from anthropogenic stressors. Understanding the connectivity dynamics among these putative refugia and more degraded reefs is critical to develop effective management strategies that promote coral metapopulation persistence and recovery. This study presents a geographically broad assessment of shallow (<30 m) and mesophotic (>30 m) connectivity dynamics of the depth‐generalist coral species Montastraea cavernosa. Over 750 coral genets were collected across the Northwest and Southern Gulf of Mexico, Florida, Cuba, and Belize, and ~5000 SNP loci were generated to quantify high‐resolution genetic structure and connectivity among these populations. Generally, shallow and mesophotic populations demonstrated higher connectivity to distant populations within the same depth zone than to adjacent populations across depth zones. However, exceptions to this pattern include the Northwest Gulf of Mexico and the Florida Keys which exhibited relatively high vertical genetic connectivity. Furthermore, estimates of recent gene flow emphasize that mesophotic M. cavernosa populations are not significant sources for their local shallow counterparts, except for the Northwest Gulf of Mexico populations. Location‐based differences in vertical connectivity are likely a result of diverse oceanographic and environmental conditions that may drive variation in gene flow and depth‐dependent selection. These results highlight the need to evaluate connectivity dynamics and refugia potential of mesophotic coral species on a population‐by‐population basis and to identify stepping‐stone populations that warrant incorporation in future international management approaches.
Gharial (Gavialis gangeticus) conservation in Bardia National Park, Nepal: Assessing population structure and habitat characteristics along the river channel amidst infrastructure development
Authors: Dhami Bijaya , Maraseni Tek , Thapa Kanchan , K. C. Nishan , Subedi Sanskar , Gautam Shreejan , Ayer Santosh , Bayne Erin 
Published: November 2023

AbstractNepal initiated numerous hydropower and irrigation‐related infrastructure projects to enhance and promote green energy, water security, and agricultural productivity. However, these projects may pose risks to natural habitats and the well‐being of aquatic fauna, leading to significant effects on delicate ecosystems. To understand these potential impacts, it is crucial to gather reliable baseline data on the population status and habitat characteristics of species. This study specifically focuses on Gharials (Gavialis gangeticus), a critically endangered species. We recorded data on pre‐determined habitat variables at stations spaced 500 m apart along the two major river streams of Bardia National Park, as well as at locations where Gharials were sighted between February and March 2023. We used binary logistic regression with a logit link function to investigate the habitat characteristics related to the occurrence of Gharials. The presence/absence of Gharials at sampling points served as the dependent variable, while 10 other predetermined variables (ecological variables and disturbance variables) served as independent variables. Our study recorded 23 Gharials, comprising 14 adults, six sub‐adults, and three juveniles, with a sex ratio of 55.56 males per 100 females. Most individuals (83%) were found basking. Among the 10 habitat predictors, three variables (mid‐river depth, river width, and water temperature) were significantly correlated (p < .05) with the probability of Gharial occurrence. The model shows that Gharial detection probability increases with greater mid‐river depth and width and lower water temperature. This study establishes a population baseline for Gharials within the river system before the construction of large infrastructure projects, such as dams and irrigation canals. It also recommends continuous monitoring of Gharial populations after water release and/or diversion to evaluate the impact of large infrastructure projects on the population and their associated habitat characteristics. This will help enable more informed and targeted conservation efforts.
Hunting behavior and feeding ecology of Mojave rattlesnakes (Crotalus scutulatus), prairie rattlesnakes (Crotalus viridis), and their hybrids in southwestern New Mexico
Authors: Maag Dylan W. , Francioli Yannick Z. , Shaw Noelle , Soni Ashana Y. , Castoe Todd A. , Schuett Gordon W. , Clark Rulon W. 
Published: November 2023

AbstractPredators must contend with numerous challenges to successfully find and subjugate prey. Complex traits related to hunting are partially controlled by a large number of co‐evolved genes, which may be disrupted in hybrids. Accordingly, research on the feeding ecology of animals in hybrid zones has shown that hybrids sometimes exhibit transgressive or novel behaviors, yet for many taxa, empirical studies of predation and diet across hybrid zones are lacking. We undertook the first such field study for a hybrid zone between two snake species, the Mojave rattlesnake (Crotalus scutulatus) and the prairie rattlesnake (Crotalus viridis). Specifically, we leveraged established field methods to quantify the hunting behaviors of animals, their prey communities, and the diet of individuals across the hybrid zone in southwestern New Mexico, USA. We found that, even though hybrids had significantly lower body condition indices than snakes from either parental group, hybrids were generally similar to non‐hybrids in hunting behavior, prey encounter rates, and predatory attack and success. We also found that, compared to C. scutulatus, C. viridis was significantly more active while hunting at night and abandoned ambush sites earlier in the morning, and hybrids tended to be more viridis‐like in this respect. Prey availability was similar across the study sites, including within the hybrid zone, with kangaroo rats (Dipodomys spp.) as the most common small mammal, both in habitat surveys and the frequency of encounters with hunting rattlesnakes. Analysis of prey remains in stomachs and feces also showed broad similarity in diets, with all snakes preying primarily on small mammals and secondarily on lizards. Taken together, our results suggest that the significantly lower body condition of hybrids does not appear to be driven by differences in their hunting behavior or diet and may instead relate to metabolic efficiency or other physiological traits we have not yet identified.
Predictability of commodity futures returns with machine learning models
Authors: Wang Shirui , Zhang Tianyang 
Published: November 2023

AbstractWe use prevailing machine learning models to investigate the predictability of futures returns in 22 commodities with commodity‐specific and macroeconomic factors as predictors. Out‐of‐sample prediction errors for the majority of futures contracts are lowered compared with those obtained by the baseline models of AR(1) and forecast combinations. Using Shapley values to explain feature importance, we identify dominant predictors for each commodity. A long–short portfolio strategy based on monthly light gradient‐boosting machine predictions outperforms the benchmark linear models in terms of annual return, Sharpe ratio, and max drawdown.
Incremental health care resource utilization and costs associated among patients with Parkinson's disease psychosis and incident dementia: An analysis of medicare beneficiaries
Authors: Rajagopalan Krithika , Rashid Nazia , Gopal Daksha , Doshi Dilesh 
Published: November 2023

AbstractBackgroundReal‐world evidence examining the incremental health care resource use (HCRU) and cost burden of incident dementia among patients with Parkinson's disease psychosis (PDP) are needed within the United States (US).ObjectivesTo compare HCRU and cost burden between PDP patients with incident dementia (PDP + D) versus without incident dementia (PDP).MethodsA retrospective analysis of inpatient (Part A), outpatient (Part B), and prescription drug (Part D) claims from the 100% Medicare sample was conducted to compare PDP + D patients versus PDP patients between 01/01/14‐12/31/18. Patients with a diagnosis of dementia, psychosis, secondary parkinsonism, or other psychotic disorders, during 12‐month pre‐index were excluded. Patients in both groups were matched using 1:1 propensity score matching (PSM) methodology using 31 variables (age, sex, race, region and 27 Elixhauser comorbidity characteristics). Differences in 12‐month post‐index HCRU rates and mean per patient per year (PPPY) costs for all‐cause inpatient (IP) hospitalizations, and by type of IP stay (i.e., short‐term [ST‐stay], skilled nursing facility [SNF‐stay] and long‐term [LT‐stay]) were analyzed via logistic and gamma log‐link regression models.ResultsOf the 12,484 patients who met our study criteria, 1855 PSM‐matched cohorts were identified. Mean age, gender, and comorbidities were similar in PSM groups. Approximately, 50.3% with PDP + D reported ≥1 all‐cause IP hospitalizations versus 36.0% with PDP (p < 0.05) during 12‐month follow‐up. Specifically, all‐cause ST‐stay, SNF‐stay, and LT‐stay among PDP + D versus PDP patients were: 45.2% versus 35.7%, 28.3% versus 15.7%, and 8.5% versus 6.0% (p < 0.05), respectively. Psychiatric‐related ST‐stay, SNF‐stay, and LT‐stay among PDP + D versus PDP patients were: 12.3% versus 9.0%, 7.5% versus 3.4%, and 2.4% versus 1.2% (p < 0.05), respectively. Mean PPPY all‐cause IP hospitalization costs for PDP + D patients versus PDP patients was $17,891 (±29,882) versus $11,599 (±$25,247) (p < 0.05).ConclusionsPatients with PDP + D experience significantly higher all‐cause and psychiatric‐related IP hospitalizations, including ST‐stays, LT stays, and SNF stays. They also had 54% greater mean PPPY IP hospitalization costs versus PDP patients.
The influence of environmental factors on the health of the population of the Aktobe region
Authors: Moldayazova Lyazzat , Zhapalakov Baser , Shagatayeva Bibigul , Kuatbaeva Aynagul , Baspakova Akmaral 
Published: November 2023

Abstract
This study investigates the impact of environmental factors on human health, including harmful substances, extreme temperatures, and air quality. The health status of the population in regions where many industries operate also depends on meteorological factors. The purpose of the study is to characterize and determine the influence of environmental factors (humidity, temperature, wind) and industries, including metal mining and processing regions, on the health of people in the Aktobe region, Republic of Kazakhstan. The study used general theoretical methods to analyze and systematize the results of the meteorological service of the Aktobe region and the experiments conducted by the branch of the National Centre of Expertise of the Committee of Sanitary and Epidemiological Control of the Ministry of Healthcare of the Republic of Kazakhstan for the Aktobe region in 2020 and 2021. Statistical data on the amount of chromium, lead, and nickel in the blood, and the morbidity rate of the population were analyzed. The study's findings indicate that residents in the Aktobe region experience hypothermia during winter at temperatures between −12 °C and −15 °C and humidity of 81%, and in summer overheating occurs at temperatures between +19.6 °C and +22.5 °C with humidity of 77%. These extreme temperature conditions disrupt the body's heat exchange with the environment, affecting the respiratory and circulatory systems. Moreover, the predominantly windless conditions in the region affect the atmosphere's self-cleaning ability, resulting in high levels of air pollution throughout the year. The findings can inform strategies to improve public health and prevent diseases in industrial regions. Integr Environ Assess Manag 2024;20:1156–1165. © 2023 SETAC
Key Points
The study emphasizes the significant relationship between environmental conditions and human health, advocating thorough research into how different environmental factors affect people's health. A critical insight from the research is the effect of natural conditions on health, where extreme cold and heat paired with high humidity levels significantly impair the body's thermoregulation, leading to hypothermia or overheating. Environmental improvements and human health protections are integral to ensuring a sustainable and prosperous future and should be a focal point of national policy and public health objectives.
Comparison of perioperative surgical outcomes between contained and free manual vaginal morcellation of large uteruses following total laparoscopic hysterectomy
Authors: Raimondo Diego , Raffone Antonio , Franceschini Camilla , Virgilio Agnese , Palermo Roberto , Borghese Giulia , Maletta Manuela , Borgia Alessandra , Neola Daniele , Travaglino Antonio , Lenzi Jacopo , Guida Maurizio , Seracchioli Renato 
Published: November 2023

AbstractObjectiveTo compare contained and free manual vaginal morcellation of large uteruses after total laparoscopic hysterectomy (TLH) in women at low risk of uterine malignancy in terms of feasibility and safety.MethodsA single‐center, observational, retrospective, cohort study was carried out including all patients undergoing TLH requiring manual vaginal morcellation for specimen extraction of large uteruses from January 2015 to August 2021 at the Division of Gynecology and Human Reproduction Physiopathology, IRCCS Azienda Ospedaliero‐Universitaria of Bologna, Bologna, Italy. Patients were divided into two groups according to the type of manual vaginal morcellation (contained or free), and compared in terms of demographic, clinical, and perioperative data.ResultsIn all, 271 patients were included: 186 (68.6%) in the contained morcellation group and 85 (31.4%) in the free morcellation group. The mean operative time was significantly lower in the contained morcellation group compared with the free morcellation group (median [interquartile range] 130 [45] vs. 155 [60] min; P < 0.001). No significant difference was found in complications related to the morcellation step, overall, intraoperative and postoperative complications, estimated blood loss, length of hospital stays, uterine weight, and rate of occult malignancy between the two groups.ConclusionContained vaginal manual morcellation of the uterus after total laparoscopic hysterectomy using a specimen retrieval bag appears to be a safe procedure with significantly lower operative time than free vaginal manual morcellation.
Using structural equation modeling to examine counselor interpersonal stress theory
Authors: Moore C. Missy , Stubbs‐Brown Breanna V. , Wood Katherine M. , Bingham Austen 
Published: November 2023

AbstractWhen counselors experience interpersonal stress, they appraise counseling events using a similar appraisal process as the well‐known stress theory, the Transactional Model of Stress and Coping. Using structural equation modeling, we tested a mediation model representing the appraisal process in counselor interpersonal stress theory using a sample of professional counselors (n = 221). We hypothesized preventive resources and counseling self‐efficacy would partially mediate the relationship between counselor interpersonal stress and counselor burnout. In the model, counselor interpersonal stress and preventive resources showed statistically significant direct effects on counselor burnout. Preventive resources partially mediated the relationship between counselor interpersonal stress and counselor burnout. Implications for clinical practice and counselor wellness are discussed.
Synthesis of porous silica from wasted SiO2‐containing molding compounds
Authors: Lai Luo‐Yun , Chang Chi‐Cheng , Hung Yi‐Lun , Chiang Tzu‐Hsing , Lin Hong‐Ping , Hsu Chun‐Han 
Published: November 2023

AbstractMaterialsIn this study, we provided a simple method to extract the silicate species from the waste silica‐containing molding compounds from the semiconducting industry.MethodsRecycled sodium silicate solution was obtained from alkaline extraction of the silica fillers in the waste molding compounds and dried and redissolved in appropriate amount of water.ResultsPorous silica of high surface area (>500 m2g−1) and tunable pore size (1.5–5.0 nm) could be feasibly synthesized by using the recycled sodium silicate as silica source and nature‐friendly homopolymer polyethylene glycol (PEG) as an organic template. The pore size of the PEG‐templating silicas was made tunable by hydrothermal treatment at different pH.ConclusionTo reduce the emission of CO2 gas from the removal of the PEG template, porous silica with a large surface area has been prepared at a low PEG/sodium silicate weight ratio of 1/20.