bluuebunny/crossref_metadata_2025_split huggingface dataset:
Sublimation enthalpies of organic compounds by isothermal thermogravimetry
Authors: Treviño-Kauffmann Marco Antonio , Esparza-Rivera Daniel , Rojas Aarón 
Published: February 2024

AbstractAn improved method has been developed to determine the sublimation enthalpies of solid organic compounds using thermogravimetric analysis and applying an isothermal methodology with a TA Instruments® SDTQ600 equipment. This was achieved by measuring the rate of mass loss as a function of the temperature from isothermal experiments in an interval of temperature of 10 to 20 K below the melting temperature of the sample. The resulting rates of mass loss were used by applying the Pieterse and Focke equation, then combined with the integrated Clausius–Clapeyron equation to calculate the heat of sublimation at the experimental temperature and it was corrected to T = 298.15 K. In order to demonstrate the reliability of this methodology, the results for benzoic acid, pyrene and phenanthrene are presented, which are respectively primary, secondary, and tertiary reference compounds in the measurement of enthalpies of sublimation, along with the sublimation enthalpies of picolinic acid, nicotinic acid and isonicotinic acid which are three pyridinecarboxylic acids isomers with the carboxyl group in the ortho, meta and para position, respectively, to the nitrogen of the pyridine.
A multi-scale approach to study palm-weevils in a tropical agroecosystem
Authors: Vásquez-Ordóñez Aymer Andrés , Torres-López Wilmar , Monmany-Garzia A. Carolina 
Published: February 2024

Abstract
Context
The recent phytosanitary crisis caused by the stem borer weevils Dynamis borassi and Rhynchophorus palmarum in peach palms (Bactris gasipaes) seriously affects the economy of rural families in Colombia. To understand the possible ecological mechanisms favoring the pest, the weevil-palm system needs to be studied from a multi-scale perspective.

Objectives
We evaluated the combined effects of agricultural management, landscape, topography, soil, and climate variables on infestation levels of peach palm caused by the weevils D. borassi and R. palmarum in the Colombian southwest to understand underlying ecological drivers of the current phytosanitary crisis.

Methods
The palm infestation levels (response variable) and local agronomic practices were recorded in 32 sites across Colombia's Pacific, Andes, and Amazon natural regions. For each peach palm crop, landscape variables were estimated from classified Sentinel-2 images, soil variables were extracted from the Soil Grids 250 m database, and climate variables were extracted from the CHIRPS and CHIRTS databases. Explanatory variables were analyzed using Generalized Linear Models and Partial Least Squares-Generalized Linear Models.

Results
Landscape variables, specifically the number and shape of non-forest patches, had a greater influence on peach palm infestation levels than other environmental variables, possibly related to the decrease in the density of Oenocarpus batatua, the natural palm host for D. borassi, leading it to switch to the peach palm.

Conclusions
A multi-scale approach of the weevil-palm interaction enabled us to identify an ecological mechanism that has not been proposed before. Our recommendation for families depending on peach palm is to design palm management with a landscape perspective that considers the conservation of alternative hosts for the weevils in agroforestal plots.
A double-bounded risk-risk trade-off analysis of heatwave-related mortality risk: Evidence from India
Authors: Chilton Susan , Duxbury Darren , Mussio Irene , Nielsen Jytte Seested , Sharma Smriti 
Published: February 2024

AbstractAs climate variability is increasing, extreme events such as temperature fluctuations are expected to become more frequent. Low- and middle-income countries (LMICs) are especially vulnerable to heat-related variability and its ensuing impacts on mortality. Therefore, there is an urgent need to understand how citizens in LMICs trade-off climate-related mortality risks with other risks such as traffic accidents, and what values they place on reducing such risks. As populations in LMICs are income-constrained, we adopt a non-monetary, risk-risk trade-off (RRTO) valuation method instead of the standard willingness-to-pay stated preference-based approach. We estimate the resulting risk premium for heatwave-related mortality risks through an adapted double-bounded, dichotomous choice approach to establish whether, on average, people value avoiding these risks more compared to reducing traffic risks. Using a sample of over 2,300 individuals from across seven states in India, a country with one of the highest heat-related mortality globally, we estimate the heatwave risk mortality premium to be between 2.2–2.9, indicating that on average, individuals weigh reducing heatwave-related mortality risks more than two times that of reducing traffic accident mortality risks. Based on a standard benefit transfer methodology for LMICs, this premium translates to a Value of Statistical Life (VSL) of USD 0.37–2.61 million for India.
Learning from different types of failure: evidence from non-severe and severe work accidents in SMEs
Authors: Lafuente Esteban 
Published: February 2024

Abstract
This paper investigates the learning patterns of small and medium-sized enterprises (SMEs) from heterogeneous work accidents (i.e., minor and severe and fatal accidents). Work safety cannot be overlooked, and the focus of this study on learning from failure allows to understand how SMEs match safety problems with solutions generated by past experience with work accidents and knowledge acquisition; while acknowledging that accident heterogeneity influences SMEs’ learning. The analysis uses a sample of 108 Spanish SMEs during 2006–2009. The results show that SMEs learn to modify safety practices, and that experience with both minor and severe and fatal accidents impact learning outcomes—measured as changes in the unit accident cost—through different mechanisms. Cumulative experience with past work accidents supports exploitative learning, but this effect was found only for minor accidents. Although the adoption of safety-enhancing tools (i.e., OHSAS 18001) does not affect learning, the findings reveal the value of ambidextrous learning: SMEs adopting the OHSAS 18001 learn more from severe and fatal accidents than from minor accidents by triggering drastic modifications in their safety practices.
The McNish and Lincoln Solar-Activity Predictions: The Method and Its Performance
Authors: Clette Frédéric , Jain Shantanu , Podladchikova Tatiana 
Published: February 2024

AbstractThe McNish and Lincoln (ML) method, introduced in 1949, was one of the first attempts to produce midterm forecasts of solar activity, up to 12 months ahead. However, it has been poorly described and evaluated in the past literature, in particular its actual operational implementation by NOAA. Here, we reconstruct the exact formulation of the method, as it was applied since the early 1970s, and we provide a full mathematical derivation of the prediction errors. For bench-marking the method, we also produce monthly predictions over the past 190 years, from 1833 (Cycle 8) to 2023 (Cycle 25), and develop statistics of the differences between the predictions and the observed 13-month smoothed sunspot-number (SSN) time series, according to the phase in the solar cycle. Our analysis shows that the ML method is heavily constrained because it is primarily based on the mean of all past cycles, which imposes a fixed amplitude and length and suffers from a temporal smearing that grows towards the end of the solar cycle. We find that predictions are completely unreliable in the first 12 months of the cycle, and over the last two years preceding the ending minimum (around 130 months), and beyond this minimum. By contrast, in the course of the cycle (months 18 to 65), ML predictions prove to be reliable over a time range of up to 50 months (4.2 years), thus much longer than the 12-month conventional range used so far. However, we find that predictions then suffer from systematic under-(over-)estimates for cycles that have a higher (lower) amplitude than the base mean cycle. Overall, we conclude that although the ML method provides valid prediction errors, it suffers from strong limitations, with very little room for improvement, as it indifferently merges all past cycles into a single fixed statistics.
Can Community Music Contribute to More Equitable Societies? A Critical Interpretive Synthesis
Authors: Bartleet Brydie-Leigh , Heard Emma 
Published: February 2024

AbstractThis article presents outcomes from a critical interpretive synthesis inquiry exploring whether community music can contribute to more equitable societies. Drawing on 74 cross-disciplinary articles, we identify equity-related outcomes across three key categories: outcomes to improve the immediate wellbeing and life trajectories for individuals experiencing disadvantage; outcomes relating to the development of skills, knowledge and understandings empowering individual participants to enact positive social change within their communities; and outcomes with the potential to affect the root causes of social inequity. This review provides a solid foundation for further conceptual and theoretical development within and beyond the fields of social justice research and community music. Our findings will also be helpful for translating the creative and cultural benefits that community music practice could bring to addressing social justice issues in a wide range of complex contexts.
Long-Term Evolution of the Saturnian System
Authors: Ćuk Matija , El Moutamid Maryame , Lari Giacomo , Neveu Marc , Nimmo Francis , Noyelles Benoît , Rhoden Alyssa , Saillenfest Melaine 
Published: February 2024

AbstractHere we present the current state of knowledge on the long-term evolution of Saturn’s moon system due to tides within Saturn. First we provide some background on tidal evolution, orbital resonances and satellite tides. Then we address in detail some of the present and past orbital resonances between Saturn’s moons (including the Enceladus-Dione and Titan-Hyperion resonances) and what they can tell us about the evolution of the system. We also present the current state of knowledge on the spin-axis dynamics of Saturn: we discuss arguments for a (past or current) secular resonance of Saturn’s spin precession with planetary orbits, and explain the links of this resonance to the tidal evolution of Titan and a possible recent cataclysm in the Saturnian system. We also address how the moons’ orbital evolution, including resonances, affects the evolution of their interiors. Finally, we summarize the state of knowledge about the Saturnian system’s long-term evolution and discuss prospects for future progress.
Practical perceptual representations: a contemporary defense of an old idea
Authors: Springle Alison A. , Buccella Alessandra 
Published: February 2024

AbstractAccording to ‘orthodox’ representationalism, perceptual states possess constitutive veridicality (truth, accuracy, or satisfaction) conditions. Typically, philosophers who deny orthodox representationalism endorse some variety of anti-representationalism. But we argue that these haven’t always been, and needn’t continue to be, the only options. Philosophers including Descartes, Malebranche and Helmholtz appear to have rejected orthodox representationalism while nonetheless endorsing perceptual representations of a fundamentally practical kind not captured by orthodox representationalism. Moreover, we argue that the perceptual science called on by contemporary philosophers to defend orthodox representationalism instead motivates a return to this older view, and we suggest that contemporary philosophers may conceptualize fundamentally practical perceptual representations as‘de agendo’representations, a species of representation that has constitutive appropriateness rather than veridicality conditions.
Evaluation of different QuEChERS-based methods for the extraction of 48 wastewater-derived organic contaminants from soil and lettuce root using high-resolution LC-QTOF with MRMHR and SWATH acquisition modes
Authors: Montemurro Nicola , Manasfi Rayana , Chiron Serge , Perez Sandra 
Published: February 2024

AbstractThe reuse of treated wastewater in agriculture is an important route of introducing a large number of organic contaminants into the agroecosystem. In this study, a modified QuEChERS-based approach was developed for rapid, simple, and simultaneous extraction of 48 organic wastewater-derived contaminants from soil and lettuce root. Twenty-two different (modification) scenarios of the known (or original) QuEChERS method have been tested, in order to obtain best and well-compromised recoveries for all target compounds for soil and roots. Finally, a common method was chosen for both matrices consisting of a single extraction step using EDTA-Mcllvaine buffer and the unbuffered Original QuEChERS salts. Method performance was accomplished by liquid chromatography coupled with high-resolution mass spectrometry on a QToF-MS system using two different acquisition modes, the ultra-fast high-resolution multiple reaction monitoring (MRMHR) mode and the innovative Sequential Window Acquisition of All Theoretical Fragment-Ion (SWATH) mode. Performance characterization was evaluated in terms of recovery, linearity, intra-day precision, method detection limits (MDLs), method quantification limits (MQLs), and matrix effect (ME). Recoveries in MRMHR mode ranged from 63 to 111% and 54 to 104% for lettuce root and soil, respectively, for most of compounds in MRMHR mode and from 56 to 121% and 54 to 104% for lettuce root and soil, respectively, for most of compounds in SWATH. Whereas, MQLs ranged from 0.03 to 0.92 ng g−1 in MRMHR and from 0.03 to 82 ng g−1 in SWATH for lettuce root, and from 0.02 to 0.44 ng g−1 in MRMHR and 0.02 to 0.14 ng g−1 in SWATH for soil. The method was then applied to follow the target compounds in soil and lettuce root, where the system lettuce-soil was irrigated with treated wastewater under real greenhouse conditions. Five and 17 compounds were detected in lettuce root and soil, respectively.
Graphical Abstract
Prediction of antenatal bleeding and preterm deliveries using placental magnetic resonance imaging in patients with placenta previa
Authors: Otake Yuko , Ugajin Atsushi , Takahashi Hironori , Tanaka Yuya , Fujii Hiroyuki , Matsuki Mitsuru , Mori Harushi 
Published: February 2024

Abstract
Purpose
This study aimed to clarify associations between subacute hematoma on placental magnetic resonance imaging (MRI), antenatal bleeding, and preterm deliveries in patients with placenta previa (PP) without placenta accreta spectrum (PAS).

Materials and methods
This retrospective study investigated 78 consecutive patients with PP (median age, 34.5 years; interquartile range [IQR], 31–37 years) who underwent placental MRI in the third trimester. Patients with PAS detected intraoperatively or pathologically were excluded. Two radiologists evaluated the presence of subacute hematomas and their locations on placental MRI. We examined associations between presence of subacute hematoma and antenatal bleeding, emergency cesarean section (CS), hysterectomy, gestational age (GA) at delivery, birth weight, and amount of blood loss at CS. We also examined the association between perinatal outcome and subacute hematoma location: marginal, retro-placental, or intra-placental. Inter-observer agreement for the detection of subacute hematoma was calculated using kappa analysis.

Results
Subacute hematomas were identified on MRI in 39 of the 78 patients (50.0%). Antenatal bleeding and emergency CS were more prevalent in patients with subacute hematoma on MRI (20 patients [51.3%] and 18 patients [46.2%], respectively) than in patients without (7 patients [17.9%], Fisher’s exact test, p = 0.004 and 7 patients [17.9%], p = 0.014, respectively). GA at delivery was significantly lower in patients with subacute hematoma (median 36w3d, IQR 35w4d–37w1d) than in patients without (median 37w1d, IQR 36w4d–37w2d; Mann–Whitney test: p = 0.048). Marginal hematoma was significantly associated with antenatal bleeding and emergency CS. Inter-observer agreement for the presence of subacute hematoma was moderate (κ = 0.573).

Conclusion
Subacute hematoma on placental MRI was associated with antenatal bleeding, emergency CS and shorter GA at delivery in patients with PP. Marginal hematoma was also associated with antenatal bleeding and emergency CS. Placental MRI appears useful for predicting antenatal bleeding and preterm delivery in patients with PP.
Factors that influence the extraction methods of terpenes from natural sources
Authors: González-Hernández Ricardo A. , Valdez-Cruz Norma A. , Trujillo-Roldán Mauricio A. 
Published: February 2024

AbstractDue to their various applications, terpenes and terpenoids are secondary metabolites of industrial interest. These compounds can be found in a wide variety of organisms from virtually all biological kingdoms. However, it has been identified that various factors in the production process, such as the place and time of harvest, pretreatments, extraction, and purification, generate differences in the profile of terpenes and terpenoids that can be obtained from organisms. The first factor that influences the extraction of compounds is drying since an inappropriate choice of the drying method can lead to the loss of the compounds of interest or the appearance of others that arise due to the decomposition of the original molecules. Similarly, Soxhlet extraction is the most used method in the recovery of terpenoids due to its high extraction efficiency. However, unconventional extraction methods have proven to be effective alternatives for terpenoid recovery, particularly the use of microwave and high-pressure extraction, as well as the use of unconventional solvents, achieving extraction efficiencies equal to or greater than Soxhlet in shorter times. This review will address the differences observed in the extraction of terpenoids and the main factors that cause them, as well as a comparison of the advantages and disadvantages of the various methodologies for drying, extraction, and separation of these compounds.
Harnessing the Potential of Real-World Evidence in the Treatment of Colorectal Cancer: Where Do We Stand?
Authors: van Nassau Sietske C. M. W. , Bol Guus M. , van der Baan Frederieke H. , Roodhart Jeanine M. L. , Vink Geraldine R. , Punt Cornelis J. A. , May Anne M. , Koopman Miriam , Derksen Jeroen W. G. 
Published: February 2024

Opinion statementTreatment guidelines for colorectal cancer (CRC) are primarily based on the results of randomized clinical trials (RCTs), the gold standard methodology to evaluate safety and efficacy of oncological treatments. However, generalizability of trial results is often limited due to stringent eligibility criteria, underrepresentation of specific populations, and more heterogeneity in clinical practice. This may result in an efficacy-effectiveness gap and uncertainty regarding meaningful benefit versus treatment harm. Meanwhile, conduct of traditional RCTs has become increasingly challenging due to identification of a growing number of (small) molecular subtypes. These challenges—combined with the digitalization of health records—have led to growing interest in use of real-world data (RWD) to complement evidence from RCTs. RWD is used to evaluate epidemiological trends, quality of care, treatment effectiveness, long-term (rare) safety, and quality of life (QoL) measures. In addition, RWD is increasingly considered in decision-making by clinicians, regulators, and payers. In this narrative review, we elaborate on these applications in CRC, and provide illustrative examples. As long as the quality of RWD is safeguarded, ongoing developments, such as common data models, federated learning, and predictive modelling, will further unfold its potential. First, whenever possible, we recommend conducting pragmatic trials, such as registry-based RCTs, to optimize generalizability and answer clinical questions that are not addressed in registrational trials. Second, we argue that marketing approval should be conditional for patients who would have been ineligible for the registrational trial, awaiting planned (non) randomized evaluation of outcomes in the real world. Third, high-quality effectiveness results should be incorporated in treatment guidelines to aid in patient counseling. We believe that a coordinated effort from all stakeholders is essential to improve the quality of RWD, create a learning healthcare system with optimal use of trials and real-world evidence (RWE), and ultimately ensure personalized care for every CRC patient.
Effect of Osteoporosis Treatments on Osteoarthritis Progression in Postmenopausal Women: A Review of the Literature
Authors: Ho Wang-Chun , Chang Chung-Chih , Wu Wen-Tien , Lee Ru-Ping , Yao Ting-Kuo , Peng Cheng-Huan , Yeh Kuang-Ting 
Published: February 2024

Abstract
Purpose of Review
The purpose of this literature review was to determine if medications used to treat osteoporosis are also effective for treating osteoarthritis (OA).

Recent Findings
A total of 40 relevant articles were identified. Studies were categorized into those (1) discussing estrogen and selective estrogen receptor modulators (SERMs), (2) bisphosphonates, (3) parathyroid hormone (PTH) analogs, and (4) denosumab, and (5) prior review articles. A large amount of evidence suggests that estrogen and SERMs are effective at reducing OA symptoms and disease progression. Evidence suggests that bisphosphonates, the most common medications used to treat osteoporosis, can reduce OA symptoms and disease progression. In vivo studies suggest that PTH analogs may improve the cartilage destruction associated with OA; however, few human trials have examined its use for OA. Denosumab is approved to treat osteoporosis, bone metastases, and certain types of breast cancer, but little study has been done with respect to its effect on OA.

Summary
The current evidence indicates that medications used to treat osteoporosis are also effective for treating OA. Estrogen, SERMs, and bisphosphonates have the most potential as OA therapies. Less is known regarding the effectiveness of PTH analogs and denosumab in OA, and more research is needed.
Nervous System Response to Neurotrauma: A Narrative Review of Cerebrovascular and Cellular Changes After Neurotrauma
Authors: Ali Hossam Tharwat , Sula Idris , AbuHamdia Abrar , Elejla Sewar A. , Elrefaey Ahmed , Hamdar Hiba , Elfil Mohamed 
Published: February 2024

AbstractNeurotrauma is a significant cause of morbidity and mortality worldwide. For instance, traumatic brain injury (TBI) causes more than 30% of all injury-related deaths in the USA annually. The underlying cause and clinical sequela vary among cases. Patients are liable to both acute and chronic changes in the nervous system after such a type of injury. Cerebrovascular disruption has the most common and serious effect in such cases because cerebrovascular autoregulation, which is one of the main determinants of cerebral perfusion pressure, can be effaced in brain injuries even in the absence of evident vascular injury. Disruption of the blood–brain barrier regulatory function may also ensue whether due to direct injury to its structure or metabolic changes. Furthermore, the autonomic nervous system (ANS) can be affected leading to sympathetic hyperactivity in many patients. On a cellular scale, the neuroinflammatory cascade medicated by the glial cells gets triggered in response to TBI. Nevertheless, cellular and molecular reactions involved in cerebrovascular repair are not fully understood yet. Most studies were done on animals with many drawbacks in interpreting results. Therefore, future studies including human subjects are necessarily needed. This review will be of relevance to clinicians and researchers interested in understanding the underlying mechanisms in neurotrauma cases and the development of proper therapies as well as those with a general interest in the neurotrauma field.