bluuebunny/crossref_metadata_2025_split huggingface dataset:
Intravascular lithotripsy: A novel option for severe calcification of coronary artery
Authors: Lv He , Li Xinyu , Ren Zengduoji , Ma Xuelian , Qin Zhilu , Fu Qiang 
Published: November 2023

AbstractBackgroundSevere coronary artery calcification is associated with low success rate of interventional operation, perioperative adverse cardiac events, and poor prognosis, which is a major problem faced by operators. The existing therapy methods all have inherent limitations, such as unsatisfactory balloon crossability, inadequate balloon dilation, and so on. The emergence of intravascular lithotripsy (IVL) has brought the dawn of the treatment of calcified lesions by using unfocused acoustic pressure waves to fracture calcification in situ. And IVL is the only technology capable of targeting deep calcification.HypothesisIVL may have great clinical application values and potential prospects.MethodBased on the existing clinical evidence of IVL and traditional treatment ways, this review discusses the safety and efficacy of IVL. Combined with clinical practice, the precautions and coping strategies of IVL are analyzed. And the review improves the management algorithm of coronary calcification.ResultsIVL has extremely high safety and effectiveness for severe coronary calcification compared with other ways, and structural improvements of IVL will further expand its value.ConclusionsThe emergence of IVL could set off a revolution in the treatment of coronary artery calcification.
Primary mitral regurgitation: Toward a better quantification on left ventricular consequences
Authors: Neveu Antoine , Aghezzaf Samy , Oger Emmanuel , L'official Guillaume , Curtis Elizabeth , Galli Elena , Montaigne David , Coisne Augustin , Donal Erwan 
Published: November 2023

AbstractBackgroundLeft ventricular end‐systolic diameter (LVESD) and ejection fraction (LVEF) are the parameters to look for when discussing repair in asymptomatic patients with a primary mitral regurgitation (PMR). Loading conditions are altering LV‐function quantification. LV‐myocardial work (LVMW) is a method based on pressure‐strain loops.HypothesisWe sought to evaluate the additive value of the LVMW for predicting clinical events in patients with PMR.Methods103 patients (66% men, median age 57 years) with asymptomatic severe PMR were explored at rest and during an exercise stress echocardiography. LV myocardial global work index (GWI), constructive work (GCW), wasted work (GWW), and work efficiency (GWE) were measured with speckle‐tracking echocardiography at rest and low workload. The indication for surgery was based on the heart teams' decision. The median follow‐up was 670 days.ResultsClinical events occurred for 50 patients (48.5%) with a median of event‐free survival distribution of 289 days. Systolic pulmonary artery pressure (sPAP) at rest was 32.61 ± 8.56 mmHg and did not predict the risk of event like LVEF and LVESD. Changes in, GLS (hazard ratio [HR] 0.55; 95% confidence interval (Cl): 0.36–0.83; p = .005), GWI (HR 1.01; 95% Cl: 1.00–1.02; p = .002) and GCW (HR 1.85; 95% Cl: 1.28–2.68; p = .001) in addition to Left Atrial Volume Index (HR 1.73; 95% CI: 1.28 – 2.33; p < 0,001) were independent predictors of events.ConclusionChanges in myocardial work indices related to low‐dose exercise are relevant to best predict PMR patient prognosis It might help to better select patient's candidate for “early‐surgery.”
Efficient nonlinear homogenization of bones using a cluster‐based model order reduction technique
Authors: Ju Xiaozhe , Zhou Chenbin , Liang Junbo , Tao Weiming , Liang Lihua , Xu Yangjian 
Published: November 2023

AbstractWe present a reduced order model for efficient nonlinear homogenization of bones, accounting for strength difference effects and containing some well‐known plasticity models (like von Mises or Drucker‐Prager) as special cases. The reduced order homogenization is done by using a cluster‐based model order reduction technique, called cluster‐based nonuniform transformation field analysis. For an offline phase, a space–time decomposition is performed on the mesoscopic plastic strain fields, while a clustering analysis is employed for a spatial decomposition of the mesoscale RVE model. A volumetric‐deviatoric split is additionally introduced to capture the enriched characteristics of the mesoscopic plastic strain fields. For an online analysis, the reduced order model is formulated in a unified minimization problem, which is compatible with a large variety of material models. Both cortical and trabecular bones are considered for numerical experiments. Compared to conventional FE‐based RVE computations, the developed reduced order model renders a considerable acceleration rate beyond , while maintaining a sufficient accuracy level.
An 8‐week compassion and mindfulness–based exposure therapy program improves posttraumatic stress symptoms
Authors: Kummar Auretta Sonia , Correia Helen , Tan Jane , Fujiyama Hakuei 
Published: November 2023

AbstractThe persistence of posttraumatic stress symptoms (PTSS) can be debilitating. However, many people experiencing such symptoms may not qualify for or may not seek treatment. Potentially contributing to ongoing residual symptoms of PTSS is emotion dysregulation. Meanwhile, the research area of mindfulness and compassion has grown to imply emotion regulation as one of its underlying mechanisms; yet, its influence on emotion regulation in PTSS cohort is unknown. Here, we explored the potential effectiveness of an 8‐week Compassion‐oriented and Mindfulness‐based Exposure Therapy (CoMET) for individuals with PTSS using a waitlist control design. A total of 28 individuals (27 females, age range = 18–39 years) participated in the study (17 CoMET; 11 waitlist control). Following CoMET, participants reported significant decreases in PTSS severity (from clinical to non‐clinical levels), emotion dysregulation and experiential avoidance, as well as significant increases in mindfulness, self‐compassion and quality of life. Electroencephalogram‐based brain network connectivity analysis revealed an increase in alpha‐band connectivity following CoMET in a network that includes the amygdala, suggesting that CoMET successfully induced changes in functional connectivity between brain regions that play a crucial role in emotion regulation. In sum, the current study demonstrated promising intervention outcomes of CoMET in effectively alleviating the symptoms of PTSS via enhanced emotion regulation.
Annual bluegrass and creeping bentgrass tiller response to phosphate fertilizer and soil pH
Authors: McNally Brandon C. , Elmore Matthew T. , Murphy James A. , Murphy Stephanie L. 
Published: November 2023

AbstractCreeping bentgrass (CB; Agrostis stolonifera L.) grows well in low phosphorus (P) soils in monoculture, however, the soil P concentration range that provides CB an advantage over annual bluegrass (AB; Poa annua L.) in mixed swards is unknown. The objective of this research was to determine how P and soil pH influence species composition when AB and CB are established from tillers in polyculture. Replicate greenhouse experiments evaluated five P rates (0, 3, 6, 9, and 12 kg ha−1 P via triple superphosphate) and two soil pH levels (5.6 and 7.1). The highest P rate in the high pH soil resulted in the most AB cover (61%). Phosphate applied at 3 kg ha−1 P in the low pH soil provided the greatest CB cover (72%), which was fivefold greater than AB cover. All P‐receiving treatments in the low pH soil had similar green cover, but a species advantage for CB was only observed in the 3 kg ha−1 P treatment. Turfgrass quality was greatest when ≥6 kg ha−1 P was applied to low pH soil but was only slightly reduced at 3 kg ha−1 P. Regardless of pH, withholding P resulted in the lowest AB cover (<4%); however, these treatments resulted in poor turfgrass quality and low green cover (<30%). Aboveground shoot biomass increased linearly with P rate and was greater at the lower pH. In moderately acidic sand, AB was less competitive than CB when Mehlich‐3 P ranged from 4 to 6 mg kg−1.
Exploring the role of mechanical forces on tendon development using in vivo model: A scoping review
Authors: Usami Yuna , Iijima Hirotaka , Kokubun Takanori 
Published: November 2023

AbstractTendons transmit the muscle contraction forces to bones and drive joint movement throughout life. While extensive research have indicated the essentiality of mechanical forces on tendon development, a comprehensive understanding of the fundamental role of mechanical forces still needs to be impaerted. This scoping review aimed to summarize the current knowledge about the role of mechanical forces during the tendon developmental phase. The electronic database search using PubMed, performed in May 2023, yielded 651 articles, of which 16 met the prespecified inclusion criteria. We summarized and divided the methods to reduce the mechanical force into three groups: loss of muscle, muscle dysfunction, and weight‐bearing regulation. In contrast, there were few studies to analyze the increased mechanical force model. Most studies suggested that mechanical force has some roles in tendon development in the embryo to postnatal phase. However, we identified species variability and methodological heterogeneity to modulate mechanical force. To establish a comprehensive understanding, methodological commonality to modulate the mechanical force is needed in this field. Additionally, summarizing chronological changes in developmental processes across animal species helps to understand the essence of developmental tendon mechanobiology. We expect that the findings summarized in the current review serve as a groundwork for future study in the fields of tendon developmantal biology and mechanobiology.
Shining a light on elusive lynx: Density estimation of three Eurasian lynx populations in Ukraine and Belarus
Authors: Palmero Stefano , Smith Adam F. , Kudrenko Svitlana , Gahbauer Martin , Dachs Dominik , Weingarth‐Dachs Kirsten , Kashpei Irina , Shamovich Dmitry , Vyshnevskiy Denys , Borsuk Oleksandr , Korepanova Kateryna , Bashta Andriy‐Taras , Zhuravchak Rostyslav , Fenchuk Viktar , Heurich Marco 
Published: November 2023

AbstractThe Eurasian lynx is a large carnivore widely distributed across Eurasia. However, our understanding of population status is heterogeneous across their range, with some populations isolated that are at risk of reduced genetic variation and a complete lack of information about others. In many European countries, Eurasian lynx are monitored through demographic studies crucial for their conservation and management. Even so, there are only rough and fragmented population assessments from Ukraine and Belarus, despite strict protection in both countries and their importance for lynx connectivity across Europe. We monitored lynx from October 2020 to March 2021 and used camera trapping in combination with spatial capture–recapture (SCR) methods in a Bayesian framework to provide the first SCR density estimation of three lynx populations across Ukraine and Belarus, including the Ukrainian Chornobyl Exclusion Zone, southern Belarus and the Ukrainian Carpathians. Our density estimates varied within our study areas ranging from 0.45 to 1.54 individuals/100 km2. This work provides a substantial scientific component to the overall understanding of lynx conservation for a region where only broad information is available and opens the doors for further large‐scale monitoring and trend assessments. The crucial information we provide can greatly enhance the range‐wide assessments of the status of this protected species. We also discuss the implications for Eurasian lynx conservation, despite the geopolitical realities impacting species monitoring in the region. Our work serves as a baseline, not only for future conservation interventions but also to evaluate the effects of disturbance and threats to these protected populations.
The effect of experimental pollinator decline on pollinator‐mediated selection on floral traits
Authors: Brown Kaitlyn S. , Caruso Christina M. 
Published: November 2023

AbstractHuman‐mediated environmental change, by reducing mean fitness, is hypothesized to strengthen selection on traits that mediate interactions among species. For example, human‐mediated declines in pollinator populations are hypothesized to reduce mean seed production by increasing the magnitude of pollen limitation and thus strengthen pollinator‐mediated selection on floral traits that increase pollinator attraction or pollen transfer efficiency. To test this hypothesis, we measured two female fitness components and six floral traits of Lobelia siphilitica plants exposed to supplemental hand‐pollination, ambient open‐pollination, or reduced open‐pollination treatments. The reduced treatment simulated pollinator decline, while the supplemental treatment was used to estimate pollen limitation and pollinator‐mediated selection. We found that plants in the reduced pollination treatment were significantly pollen limited, resulting in pollinator‐mediated selection for taller inflorescences and more vibrant petals, both traits that could increase pollinator attraction. This contrasts with plants in the ambient pollination treatment, where reproduction was not pollen limited and there was not significant pollinator‐mediated selection on any floral trait. Our results support the hypothesis that human‐mediated environmental change can strengthen selection on traits of interacting species and suggest that these traits have the potential to evolve in response to changing environments.
Enhancing myocardial function with cardiac contractility modulation: potential and challenges
Authors: Li Zihan , Liu Qiming , Zhou Shenghua , Xiao Yichao 
Published: November 2023

AbstractCardiac contractility modulation (CCM) offers a novel therapeutic avenue for heart failure patients, particularly those unresponsive to cardiac resynchronization therapy within specific QRS duration ranges. This review elucidates CCM's mechanistic underpinnings, its impact on myocardial function, and utility across patient demographics. However, CCM is limited by insufficient data on mortality and hospitalization rate reductions, as well as the need for specialized device implantation skills. While prevailing research has concentrated on left ventricular effects, a knowledge gap persists for other patient subsets. Future inquiries should address combinatory treatment strategies, extended usage and the impact of atrial fibrillation on device implantation. Such expanded studies could refine therapeutic outcomes and widen the scope of beneficiaries.
Dehydrogenation of Aqueous Formic Acid by Iridium and Ruthenium Complexes with Nitrogen‐rich Diamino‐bis(1H‐1,2,4‐triazole)
Authors: Ge Shun , Liu Jia‐Hao , Gong Lishan , Mo Xiu‐Fang , Liu Chao , Yi Xiao‐Yi , He Piao 
Published: November 2023

AbstractThe development of efficient catalysts for the dehydrogenation of formic acid (FA) through molecular level control and precise regulation remains challenging. Herein, we report the newly developed complexes of iridium and ruthenium with nitrogen‐rich ligand for aqueous FA dehydrogenation. The Cp*Ir complex 1 (Cp*=cyclopentadienyl) and Ru(p‐cym) complex 2 (p‐cym=p‐Cymene) were synthesized and fully characterized. The single crystal structures of these complexes have a typical piano‐stool structure. A turnover frequency of 12468 h−1 was achieved for FA dehydrogenation at 90 °C by using complex 1 bearing 3,3’‐diamino‐5,5’‐bis(1H‐1,2,4‐triazole) (DABT). The effects of pH, temperature, concentration of formic acid and amount of catalyst on the reaction kinetics were studied in detail. Kinetic isotope effect (KIE) experiments and 1H NMR detection of reaction revealed that a plausible mechanism involves the decarboxylation of formate and the formation of H2. More importantly, the influence of H2O and H+ was involved in the rate‐determining step. This study demonstrated the effectiveness of nitrogen‐rich ligand for FA dehydrogenation, which would contribute to the development of new and effective hydrogen release systems.
Early versus persistent Complex Regional Pain Syndrome: Is there a difference in patient reported outcomes following rehabilitation?
Authors: Lewis Jennifer S. , Wallace Chris S. , White Paul , Mottram Laura , Ockenden Gareth , Rehm Kjetil , Walker Kate 
Published: November 2023

AbstractBackgroundExpert consensus asserts that early treatment of Complex Regional Pain Syndrome (CRPS) leads to better outcomes. Yet no evidence supports this assumption regarding the recognized gold standard of multidisciplinary functional rehabilitation. To address this, we aimed to establish if there is a difference in outcomes between early CRPS (<1 year symptom duration) and persistent CRPS (= >1 year symptom duration) following rehabilitation and whether any gains are maintained at three months.MethodSecondary analysis was conducted on previously collected clinical Patient Reported Outcome Measures (PROMS) data from 218 patients attending a residential multidisciplinary rehabilitation programme. Datasets were categorized into early CRPS (n = 40) or persistent CRPS (n = 178) dependent on symptom duration. Function, pain, self‐efficacy, kinesiophobia and psychological health domains were compared using repeated measures analysis of covariance for a two group design for group difference post rehabilitation and at three month follow‐up.ResultsPost‐rehabilitation, both groups improved in pain, function, kinesiophobia, psychological health and self‐efficacy. At three months, the persistent CRPS group maintained improvements in pain and function. This was not achieved in early CRPS.ConclusionThis exploratory study is the first to empirically test the assumption that those with early CRPS have better outcomes following rehabilitation. Our clinical data challenges this, as both early and persistent CRPS groups improved following rehabilitation. Findings indicate that rehabilitation benefits those with CRPS, regardless of symptom duration. However, unlike early CRPS, those with persistent CRPS sustain gains at follow‐up. Further prospective exploration is warranted.SignificanceExpert consensus recommends early treatment for Complex Regional Pain Syndrome, yet there is little empirical evidence to support this. Our findings are the first to challenge this assumption by revealing no difference in outcomes between early and persistent CRPS post‐rehabilitation. However, those with persistent CRPS maintain gains after three months, unlike people with early CRPS (symptoms < one year). These findings are relevant to clinical practice as they challenge established assumptions, suggesting a focus on improving early CRPS follow‐up outcomes.
Electrospun nanofibers synthesis enhancing the activity of energy storage devices/electrochemical and biosensor applications
Authors: Noor Umar , Saleem Amna , Furqan Mughal Muhammad , Sharif Ammara , Kulsum Umme , Bano Sadia , Fayyaz Farid Muhammad , Ahmed Toheed 
Published: November 2023

AbstractNanofibers have been synthesized by many methods due to its numerous applications. This article provides a thorough introduction to electrospinning here, including its history, various production techniques, common materials, and potential uses, most notably in energy storage. Electrospinning, a simple and low‐cost process, can be used to effectively manufacture nanofibers. While the method of electrospinning has been known for over a half‐century, current understanding of the process and the parameters that determine the qualities of the fibers produced by it is quite limited. This is extremely advantageous for energy devices including electrochemical (bio) sensors that give increased solar‐electric energy conversion efficiency. Apart from energy, other applications related to drug delivery, filter media and membrane like are also discussed. This article covers current advances in electrospun nanofibers, with an emphasis on their synthesis and applications.
Dye Degradation, Antimicrobial Activity, and Molecular Docking Analysis of Samarium‐Grafted Carbon Nitride Doped‐Bismuth Oxobromide Quantum Dots
Authors: Rani Shams , Imran Muhammad , Haider Ali , Shahzadi Anum , Ul‐Hamid Anwar , Somaily H. H. , Moeen Sawaira , Khan Mahreen , Nabgan Walid , Ikram Muhammad 
Published: November 2023

AbstractVarious concentrations of samarium‐grafted‐carbon nitride (Sm‐g‐C3N4) doped‐bismuth oxobromide (BiOBr) quantum dots (QDs) are prepared by the co‐precipitation method. Elemental evaluation, morphological, optical, and functional group assessment are studied employing characterization techniques. Based on the XRD pattern analysis, it is determined that BiOBr exhibits a tetragonal crystal structure. The electronic spectroscopy revealed an absorption peak for BiOBr at 315 nm and the bandgap energy (Eg) decreasing from 3.9 to 3.8 eV with the insertion of Sm‐g‐C3N4. The presence of vibrational modes related to BiOBr at 550 cm−1 is confirmed through FTIR spectra. TEM revealed that pure BiOBr possessed non‐uniform QDS, and agglomeration increased with the addition of Sm‐g‐C3N4. The catalytic performance of Sm‐g‐C3N4 into BiOBr (6 mL) in a neutral medium toward rhodamine B exhibited excellent results (99.66%). The bactericidal activity is evaluated against multi‐drug resistance (MDR) Escherichia coli once the surface area is increased by dopant and the measured inhibition zone is assessed to be 3.65 mm. Molecular docking results supported the in vitro bactericidal potential of Sm‐g‐C3N4 and Sm‐g‐C3N4 doped‐BiOBr as DNA gyraseE. coli inhibitors. This study shows that the novel Sm‐g‐C3N4 doped‐BiOBr is a better catalyst that increases specific semiconductor's catalytic activity (CA).
Estimating runoff probability from precipitation data: A binomial regression analysis
Authors: DeGuzman Kelly , Knappenberger Thorsten , Brantley Eve , Olshansky Yaniv 
Published: November 2023

AbstractThe runoff threshold of a catchment is often reported in the literature as a measure used to evaluate the effectiveness of low‐impact development (LID) techniques and is oftentimes determined using linear regression. However, due to the heteroscedastic nature of precipitation and runoff data, linear regression analyses can result in invalid conclusions, so the use of a binomial regression model was investigated. Precipitation and runoff data collected from five studies were assessed for homoscedasticity and applied to four linear regression models for the evaluation of the linear regression runoff threshold (LRRT) and the associated 95% bootstrapping confidence intervals. Log‐transformation corrected the heteroscedasticity of two of the five precipitation and runoff datasets. While mixed‐effect linear models accounted for heteroscedasticity, these models often resulted in extremely large confidence intervals. A binomial regression model was created to determine the likelihood of runoff based on precipitation depth. For each catchment, the 10%–90% runoff probability range (p10–p90) is reported to provide the user with a more comprehensive understanding of when a catchment produces runoff than the LRRT. The p10–p90 range reflects the effects that environmental factors may have on runoff generation. For example, impervious catchments with limited interaction with the vegetation and soil produce a narrow p10–p90 range. Conversely, LID practices encourage the interaction of runoff with environmental factors and result in a wider p10–p90 range. Utilization of the binomial regression methodology presented herein is recommended for evaluation of the likelihood of runoff for each precipitation depth.