bluuebunny/crossref_metadata_2025_split huggingface dataset:
USO DE TECNOLOGIA A LASER EM CIRURGIAS ORAIS: APLICAÇÕES E BENEFÍCIOS
Authors: Omena André de Almeida Agra , Filgueira Guilherme Sátyro Albuquerque , Barreto Maria Izabel Medeiros , Paula Juliana Carvalho de , Galvão Nicole Emanuela , Barbosa Júnior Walter César de Oliveira , Fonseca Filho Alexandre Herval Andrade , Veríssimo Matheus Harllen Gonçalves , Silva Jeniffer Lorrayne Gonçalves , Nóbrega Raquel Palmeira Araújo Medeiros da , Minervino Layane Kerlly Carvalho , Azevedo Jeova Mateus dos Santos , Oliveira Ocimar Lopes de , Borburema Rhuann Ayran Castro 
Published: January 2025

Abstract

Photobiomodulation (PBM) has been highlighted as a complementary therapeutic approach in dentistry, especially in the postoperative management of dental extractions and associated complications such as alveolar osteitis and inferior alveolar nerve paresthesia. Using low-intensity lasers in the red and infrared wavelengths, PBM promotes pain relief, reduction of edema and trismus, as well as accelerating tissue healing and neural regeneration. The effectiveness of PBM varies according to the protocol used, including the place of application, exposure time and number of sessions, with promising results reported in only one application on the day of surgery. For this research, the electronic databases were used: U.S National Library of Medicine (PubMed), Scientific Electronic Library Online (SciELO), ScienceDirect and Lilacs. In addition, two descriptors were used for the composition of the search key, being the following (MeSH/DeCS). After the research, it was observed that PBM demonstrates significant potential in dentistry to improve patients' quality of life and optimize post-operative recoverysurgical, but its broad incorporation into clinical practice requires more scientific evidence and adjustments to existing protocols. Keywords: Laser Therapy. Oral surgery. Dentistry.
Disaster and Disaster Risk Reduction Strategies at Different Level
Authors: Pandey Bista Archana , Dhakal Kamala , Pandey Apsara 
Published: January 2025

Background: Any form of disaster is destructive causing a large mortality, a huge environment, and economic loss with long-term adverse health consequences. Globally, Disaster Risk Reduction strategies are becoming more crucial to prepare, manage, and respond the disaster events in achieving the targets of Sustainable Developmental Goals (SDGs).
Methods: Extensive related literature been searched through different data search like google, Pubmed, Hinari by using keywords and the findings were grouped in sequential order.
Results: Disater risk reduction plans are global effort widely used among general and health population. Effective strategic interventions like sendai framework for disaster management are in use for preventing disaster risk and managing disaster consequences.
Conclusions: Disaster Risk Reduction is the comprehensive strategies and the shared responsibility of all individuals from community level involvement to Universities level preparedness, and National level interventions.
Dinamika Interaksi Manusia, Masyarakat, dan Budaya dalam Era Globalisasi dan Modernisasi
Authors: Harniati Hapsah Romlah , Az Zahrah Fatimah , Yasin Muhammad 
Published: January 2025

Humans are social creatures, humans always live in groups to interact and communicate because of their desire to connect with other people and blend in with the surrounding environment. This research focuses on what is the role of humans in forming and maintaining society and culture? and how globalization and modernization affect the relationships between people, society, and culture. This research has two objectives, namely to explain the role of humans in forming and maintaining society and culture and to explain how globalization and modernization affect the relationship between humans, society and culture. The method in this research uses qualitative methods with observation and interview techniques. The results of this research show that the role of humans in maintaining and forming society and culture is very complex and broad. Starting from forming the values ​​and norms that exist in society so that it becomes a culture that must be maintained and developed in the future. Then the influence of globalization and modernization on human relations, society and culture is very significant. However, with the positive and negative impacts of the development of globalization and modernization each bringing advantages and disadvantages to human life, therefore, we as humans must be able to balance and sort the two well.
Lire pour / avec le corps : activations sonores de la poésie de Celerina Sánchez et Víctor Gally
Authors: Lepe Lira Luz María , López Durand Mariana 
Published: January 2025

Dans cet article, nous abordons la proposition de la poétesse Celerina Sánchez et du musicien Víctor Gally, le duo Natsiká (ñuu savi [mixtèque] poésie et blues). Par le biais de diverses ressources intermédiales, ce duo se concentre sur le son pour tenter de rendre la langue tu’un savi [mixtèque] reconnaissable. Nous montrons la remédiation de deux poèmes « Nika’ín ɨɨn » et « Yo’ó ingáyu », issus du livre-disque Káku ta’án (2019), ainsi que la traduction intersémiotique entre les supports du livre imprimé (écriture bilingue tu’un savi et espagnol), le Soundcloud avec la musicalisation de l’harmonica et l’enregistrement de leur performance vidéo.
Cancer Drug Price and Novelty in Mechanism of Action
Authors: Miljković Miloš D. , Tuia Jordan , Olivier Timothée , Haslam Alyson , Prasad Vinay 
Published: December 2023

ImportanceMany economic theories point to regulatory issues and subsidization of research and development costs as the primary factor in the high cancer drug prices in the US. Even so, the association between the median annual cost and novelty of cancer drugs approved in the US remains unclear.ObjectiveTo evaluate the association between the median annual cost and novelty of cancer drugs approved in the US over a 6-year period.Design, Setting, and ParticipantsThis cross-sectional study included all cancer drugs approved by the US Food and Drug Administration (FDA) from January 1, 2015, to December 31, 2020. Drug names, indications, manufacturer, dosage, and measures of activity/efficacy were extracted from the FDA announcement. The search was performed in December 2021. Data were analyzed from January 2022 until April 2022.Main Outcomes and MeasuresAnnual cost of treatment was calculated based on average wholesale price collected from the 2021 Micromedex Red Book database. Mechanism of action was inferred from trial publication or its references.ResultsThere were 224 cancer drug approvals across 119 individual drugs, with a median annual cost of $196 000 (IQR, $170 000-$277 000). Gene and viral therapies were the most expensive (median, $448 000 [IQR, $448 000-$479 000]), followed by small molecule therapy (median, $244 000 [IQR, $203 000-$321 000), and biologics (median, $185 000 [IQR, $148 000-$195 000]). There was no significant difference in cost between first-in-class, next-in-class, and subsequent approvals of an already approved drug.Conclusions and RelevanceFindings of this study indicate that the median annual price of anticancer drugs in the US is not associated with the novelty of their mechanism of action.
Therapeutic Nanovaccines Reshape the Metabolic and Immune Microenvironment for Enhancing Immunotherapy of Primary and Lymphatic Metastatic Tumors
Authors: Fu Baixue , Hu Junwei , Yu Ao , Wang Yongjian 
Published: December 2023

AbstractThe effectiveness of anti‐metastasis therapy is hampered by the highly immunosuppressive microenvironment found in both tumor tissues and lymph nodes. In this work, a therapeutic nanovaccine, CaGlu NPs, is introduced composed of calcium carbonate nanoparticles (CaCO3 NPs) and β‐glucan. Through the synergistic effect of CaCO3 NPs and β‐glucan, CaGlu NPs can induce immunogenic cell death in tumor tissues, repolarize tumor macrophages, reverse the immunosuppressive tumor microenvironment, effectively activate antigen‐specific cytotoxic T lymphocytes, promote dendritic cells maturation, and eventually elicit an effective anti‐tumor immune response in both primary tumors and metastatic lymph nodes. Meanwhile, CaGlu NPs can remodel the metabolic microenvironment in tumors and lymph nodes by decreasing the expression of lactate dehydrogenase A and hypoxia‐inducible factor‐1α, further enhancing the anti‐tumor immune response. CaGlu NPs also inhibit tumor angiogenesis and lymphangiogenesis and induce long‐term immune memory effects. This therapeutic nanovaccine strategy, which simultaneously remodels the metabolic and immunosuppressive microenvironments in tumors and metastatic lymph nodes, showed strong anti‐metastatic effects in vivo. This study presents a promising approach to effectively treat lymph node metastatic tumors using nanomaterial‐assisted immunotherapies and underscores its broad potential for clinical applications.
In‐Plane Heterostructured MoN/MoC Nanosheets with Enhanced Interfacial Charge Transfer for Superior Pseudocapacitive Storage
Authors: Wang Cheng , Li Xiuli , Song Hao , Chu Paul K , Huo Kaifu 
Published: December 2023

Abstract2D transition metal carbide/nitride heterostructures are emerging pseudocapacitive materials for supercapacitors (SCs); however, the lack of efficient synthesis methods and an in‐depth understanding of the pseudocapacitive storage mechanism of these potentially important materials impede their applications in SCs. Herein, 2D MoN/MoC nanosheets with a precisely regulated interface are prepared controllably by a scalable salt‐assisted method with bulk MoS2 as the precursor. In operando infrared spectroscopy and electrochemical quartz crystal microbalance results reveal that the pseudocapacitance of the MoN/MoC nanosheets originates from the reversible reaction between Mo–N sites and H+ in the acidic electrolyte. Density‐functional theory calculations and X‐ray photoelectron spectroscopy disclose that the MoC/MoN heterointerface induces the internal electric field from the accumulated negative charges at the Mo–N sites by electron donation from MoC, leading to enhanced H+ adsorption at the Mo–N sites and superior pseudocapacitive storage. The heterostructured MoN/MoC nanosheets show a large volumetric capacity of 1045.3 F cm−3 at 1 A cm−3, high‐rate capability of 702.8 F cm−3 at 10 A cm−3, and superior cyclability with capacity retention of 98% after 10,000 cycles, which outperform reported Mo‐based carbides and nitrides. The results provide new insights into the development of high‐performance 2D heterostructured materials for superior pseudocapacitive storage.
High‐Yield‐Stress Particle‐Stabilized Emulsion for Form‐Factor‐Free Thermal Pastes with High Thermal Conductivity, Stability, and Recyclability
Authors: Min Seong‐Bae , Jo Yongsu , Ryu Seoung Young , Lee Joohyung , Ahn Cheol‐Woo , Kim Chae Bin 
Published: December 2023

AbstractThermal pastes, thermally conductive fillers dispersed in liquid matrices, are widely used as thermal interface materials (TIMs). TIMs transfer heat generated from electronics to the surroundings, ensuring optimal operating temperatures. Thus, it is crucial to obtain high thermal conductivity (TC) by forming a continuous heat‐conduction pathway through interconnected filler‐networks within the TIM. Therefore, for paste‐type TIMs with spherical fillers, high TC can only be realized at sufficiently high filler loadings (>60 vol%). However, the pastes bearing such high filler loadings are thick, stiff, and less applicable. To these ends, particle‐stabilized emulsions composed of immiscible liquids (silicone oil and glycerol) and spherical alumina are utilized as thermal pastes. Owing to this structure, the resulting form‐factor‐free thermal paste exhibits higher TC and stability than a simple mixture consisting of alumina and a single‐liquid‐matrix (either silicone oil or glycerol). Furthermore, the high applicability of the emulsion‐type pastes enables syringe extrusion, 3D printing, multiple cycles of reprocessing/molding, and eco‐friendly recycling.
[2.2]Paracyclophane‐Based Double Helices: Tunable Circularly Polarized Luminescence Driven by Self‐Assembly
Authors: He Jing , Fan Yanqing , Lian Zhe , Guo Shengzhu , Wang Ying , Jiang Hua 
Published: December 2023

AbstractAchieving high luminescence dissymmetry factors and quantum yields in the solid state remains a significant challenge in developing circularly polarized luminescence (CPL) materials. This study presents the synthesis of double helices based on planar chiral [2.2]paracyclophane ([2.2]PCP) and tetraphenylethylene (TPE), which exhibit chiroptical and aggregation‐induced emission (AIE) properties. In particular, the double helix with long alkyl chains demonstrates tunable CPL activity driven by self‐assembly, exhibiting dissymmetry factors ranging from 10−4 to 10−2. Notably, doped PMMA films show an amplified dissymmetry factor of 0.058 and a high quantum yield of up to 51%. The designed molecules represent an ideal molecular functional material for generating efficient CPL with controllable dissymmetry factor and high emission efficiency in the solid state. This opens up possibilities for applications in chiroptical sensing, data storage, and light‐emitting devices based on solid‐state materials.
Accelerating Nature: Induced Atomic Order in Equiatomic FeNi
Authors: Lewis Laura H. , Stamenov Plamen S. 
Published: December 2023

AbstractThe production of locally atomically ordered FeNi (known by its meteoric mineral name, tetrataenite) is confirmed in bulk samples by simultaneous conversion X‐ray and backscattered γ‐ray 57Fe Mössbauer spectroscopy. Up to 22 volume percent of the tetragonal tetrataenite phase is quantified in samples thermally treated under simultaneous magnetic‐ and stress‐field conditions for a period of 6 weeks, with the remainder identified as the cubic FeNi alloy. In contrast, all precursor samples consist only of the cubic FeNi alloy. Data from the processed alloys are validated using Mössbauer parameters derived from natural meteoritic tetrataenite. The meteoritic tetrataenite exhibits a substantially higher degree of atomic order than do the processed samples, consistent with their low uniaxial magnetocrystalline anisotropy energy of ≈1 kJ·m−3. These results suggest that targeted refinements to the processing conditions of FeNi will foster greater atomic order and increased magnetocrystalline anisotropy, leading to an enhanced magnetic energy product. These outcomes also suggest that deductions concerning paleomagnetic conditions of the solar system, as derived from meteoritic data, may warrant re‐examination and re‐evaluation. Additionally, this work strengthens the argument that tetrataenite may indeed become a member of the advanced permanent magnet portfolio, helping to meet rapidly escalating green energy imperatives.
3‐Hydroxythiophenol‐Formaldehyde Resin Microspheres Modulated by Sulfhydryl Groups for Highly Efficient Photocatalytic Synthesis of H2O2
Authors: Xu Yulu , Hu Xia , Chen Yuyuan , Lin Sijie , Wang Chen , Gou Faliang , Yang Xiaogang , Zheng Weiwei , Ma De‐Kun 
Published: December 2023

AbstractResorcinol‐formaldehyde (RF) resin represents a promising visible‐light responding photocatalyst for oxygen reduction reaction (ORR) toward H2O2 production. However, its photocatalytic ORR activity toward H2O2 generation is still unsatisfied for practical application. Herein, 3‐hydroxythiophenol‐formaldehyde (3‐HTPF) resin microspheres synthesized through polycondensation reaction between 3‐HTP and formaldehyde at room temperature and subsequent hydrothermal treatment exhibit enhanced photocatalytic ORR activity is reported. The experimental results show that the partial substitution of hydroxy group (─OH) by sulfhydryl one (─SH) through using 3‐HTP to replace resorcinol could slow the rates of nucleation and growth of the resin particles and lead to strongly π‐stacked architecture in 3‐HTPF. The introduction of ─SH group can also improve adsorption ability of 3‐HTPF to O2 molecules and enhance ORR catalytic activity of the photocatalysts. Stronger built‐in electric field, better adsorption ability to O2 molecules, and increased surface catalytic activity collectively boost photocatalytic activity of 3‐HTPF microspheres. As a result, H2O2 production rate of 2010 µm h−1 is achieved over 3‐HTPF microspheres at 273 K, which is 3.4 times larger than that obtained using RF submicrospheres (591 µm h−1). The rational substituent group modulation provides a new strategy for designing polymeric photocatalysts at the molecular level toward high‐efficiency artificial photosynthesis.
Electrodeposition Stability Landscape for Solid–Solid Interfaces
Authors: Chatterjee Debanjali , Naik Kaustubh G. , Vishnugopi Bairav S. , Mukherjee Partha P. 
Published: December 2023

AbstractAs solid‐state batteries (SSBs) with lithium (Li) metal anodes gain increasing traction as promising next‐generation energy storage systems, a fundamental understanding of coupled electro‐chemo‐mechanical interactions is essential to design stable solid‐solid interfaces. Notably, uneven electrodeposition at the Li metal/solid electrolyte (SE) interface arising from intrinsic electrochemical and mechanical heterogeneities remains a significant challenge. In this work, the thermodynamic origins of mechanics‐coupled reaction kinetics at the Li/SE interface are investigated and its implications on electrodeposition stability are unveiled. It is established that the mechanics‐driven energetic contribution to the free energy landscape of the Li deposition/dissolution redox reaction has a critical influence on the interface stability. The study presents the competing effects of mechanical and electrical overpotential on the reaction distribution, and demarcates the regimes under which stress interactions can be tailored to enable stable electrodeposition. It is revealed that different degrees of mechanics contribution to the forward (dissolution) and backward (deposition) reaction rates result in widely varying stability regimes, and the mechanics‐coupled kinetics scenario exhibited by the Li/SE interface is shown to depend strongly on the thermodynamic and mechanical properties of the SE. This work highlights the importance of discerning the underpinning nature of electro‐chemo‐mechanical coupling toward achieving stable solid/solid interfaces in SSBs.
Recent Progress on the Air‐Stable Battery Materials for Solid‐State Lithium Metal Batteries
Authors: Cheng Bingbing , Zheng Zi‐Jian , Yin Xianze 
Published: December 2023

AbstractSolid‐state lithium metal batteries (SSLMBs) offer numerous advantages in terms of safety and theoretical specific energy density. However, their main components namely lithium metal anode, solid‐state electrolyte, and cathode, show chemical instability when exposed to humid air, which results in low capacities and poor cycling stability. Recent studies have shown that bioinspired hydrophobic materials with low specific surface energies can protect battery components from corrosion caused by humid air. Air‐stable inorganic materials that densely cover the surface of battery components can also provide protection, which improves the storage stability of the battery components, broadens their processing conditions, and ultimately decreases their processing costs while enhancing their safety. In this review, the mechanism behind the surface structural degradation of battery components and the resulting consequences are discussed. Subsequently, recent strategies are reviewed to address this issue from the perspectives of lithium metal anodes, solid‐state electrolytes, and cathodes. Finally, a brief conclusion is provided on the current strategies and fabrication suggestions for future safe air‐stable SSLMBs.
Increased prevalence of aspiration pneumonitis in spontaneous cerebrospinal fluid leaks
Authors: Tang Ru , Zhou Jiayao , Zhang Shiyao , Mao Song , Zhang Weitian 
Published: December 2023

AbstractBackgroundAspiration pneumonitis (AP) secondary to cerebrospinal fluid (CSF) leak is underestimated and rarely discussed. This study aimed to evaluate the association between AP and CSF leaks.MethodsClinical and surgical characteristics of CSF leak patients with and without AP between January 2010 and December 2022 were included and compared.ResultsThis study included 159 patients, 16 with CSF otorrhea and 143 with CSF rhinorrhea. Among them, 40 (25.2%) had AP. Bilateral pneumonitis was identified in 32 cases, of which 11 showed severe pneumonitis in the right upper lung lobe. Twenty‐one (52.5%) asymptomatic and 19 (47.5%) symptomatic cases were documented. The major clinical manifestations included cough (n = 19, 47.5%) and expectoration (n = 9, 22.5%). The prevalence of pneumonitis was significantly higher in the spontaneous group than in the traumatic group. High‐flow CSF leak was associated with AP (42.5% vs. 16.8%, p = 0.001). No significant differences were identified in defect locations between patients with and without AP. Patients with pneumonitis had a higher prevalence of meningitis (32.5% vs. 12.6%, p = 0.003). Multiple logistic regression results revealed that meningitis, spontaneous and high‐flow CSF leaks are independent factors for AP occurrence. Both the CSF leak and pulmonary complications resolved following successful surgical repair.ConclusionsAP secondary to CSF leaks is frequently underdiagnosed, with a higher incidence identified in spontaneous cases. The occurrence of AP was associated with high‐flow CSF leak.Key points
A pneumonitis rate of 25.2% in cerebrospinal fluid (CSF) leak patients was reported for the first time.
A higher prevalence of aspiration pneumonitis was identified in spontaneous CSF leak.
Meningitis, spontaneous and high‐flow CSF leaks are independent factors for aspiration pneumonitis occurrence.
Improving Alkaline Hydrogen Oxidation through Dynamic Lattice Hydrogen Migration in Pd@Pt Core‐Shell Electrocatalysts
Authors: Zhao Tonghui , Li Mengting , Xiao Dongdong , Yang Xiaoju , An Lulu , Deng Zhiping , Shen Tao , Gong Mingxing , Chen Yi , Liu Hongfang , Feng Ligang , Yang Xuan , Li Li , Wang Deli 
Published: December 2023

AbstractTracking the trajectory of hydrogen intermediates during hydrogen electro‐catalysis is beneficial for designing synergetic multi‐component catalysts with division of chemical labor. Herein, we demonstrate a novel dynamic lattice hydrogen (LH) migration mechanism that leads to two orders of magnitude increase in the alkaline hydrogen oxidation reaction (HOR) activity on Pd@Pt over pure Pd, even ≈31.8 times mass activity enhancement than commercial Pt. Specifically, the polarization‐driven electrochemical hydrogenation process from Pd@Pt to PdHx@Pt by incorporating LH allows more surface vacancy Pt sites to increase the surface H coverage. The inverse dehydrogenation process makes PdHx as an H reservoir, providing LH migrates to the surface of Pt and participates in the HOR. Meanwhile, the formation of PdHx induces electronic effect, lowering the energy barrier of rate‐determining Volmer step, thus resulting in the HOR kinetics on Pd@Pt being proportional to the LH concentration in the in situ formed PdHx@Pt. Moreover, this dynamic catalysis mechanism would open up the catalysts scope for hydrogen electro‐catalysis.