bluuebunny/crossref_metadata_2025_split huggingface dataset:
Characterization of single-crystal phenothiazine synthesized using the vertical Bridgman method
Authors: Periyasamy Velusamy , Ramraj Ramesh Babu , Hasan Imran , Subramanian Prabhakaran , Kim Ikhyun , Paramasivam Sivaprakash 
Published: February 2024

Abstract
A bulk organic single crystal of phenothiazine measuring 65 mm in length and 10 mm in width was grown using the single zone vertical Bridgman technique (VBT), which was visible to the naked eye. Powder X-ray diffraction, also known as XRD, was used in order to perform crystal structural verification on the manufactured crystal. The Fourier transform infrared spectroscopy (FT-IR) approach was used in order to ascertain the crystals’ respective vibrational frequencies. In order to evaluate the single crystal’s crystalline perfection and optical quality, high-resolution X-ray diffraction rocking curve measurement (HRXRD) and UV transmittance spectrum analysis were used. So as to investigate the nonlinear optical (NLO) activity of the generated single crystals, a Q-switched and pulsed Nd: YAG laser was used in the research. This led to the discovery of the SHG efficiency. The single crystal’s mechanical strength was evaluated using Vicker’s microhardness measurement, which provided an approximation of the true value. Furthermore, the single crystal was examined and reported for its optical birefringence, photoluminescence, and refractive index.
Assessment of the impact of direct in vitro PFAS treatment on mouse spermatozoa
Authors: Calvert Leah , Martin Jacinta H , Anderson Amanda L , Bernstein Ilana R , Burke Nathan D , De Iuliis Geoffry N , Eamens Andrew L , Dun Matthew D , Turner Brett D , Roman Shaun D , Green Mark P , Nixon Brett 
Published: February 2024

Graphical abstract

Abstract
Poly- and per-fluoroalkyl substances (PFAS) are synthetic environmentally persistent chemicals. Despite the phaseout of specific PFAS, their inherent stability has resulted in ubiquitous and enduring environmental contamination. PFAS bioaccumulation has been reported globally with omnipresence in most populations wherein they have been associated with a range of negative health effects, including strong associations with increased instances of testicular cancer and reductions in overall semen quality. To elucidate the biological basis of such effects, we employed an acute in vitro exposure model in which the spermatozoa of adult male mice were exposed to a cocktail of PFAS chemicals at environmentally relevant concentrations. We hypothesized that direct PFAS treatment of spermatozoa would induce reactive oxygen species generation and compromise the functional profile and DNA integrity of exposed cells. Despite this, post-exposure functional testing revealed that short-term PFAS exposure (3 h) did not elicit a cytotoxic effect, nor did it overtly influence the functional profile, capacitation rate, or the in vitro fertilization ability of spermatozoa. PFAS treatment of spermatozoa did, however, result in a significant delay in the developmental progression of the day 4 pre-implantation embryos produced in vitro. This developmental delay could not be attributed to a loss of sperm DNA integrity, DNA damage, or elevated levels of intracellular reactive oxygen species. When considered together, the results presented here raise the intriguing prospect that spermatozoa exposed to a short-term PFAS exposure period potentially harbor an alternate stress signal that is delivered to the embryo upon fertilization.

Lay summary
PFAS are synthetic chemicals widely used in non-stick cookware, food packaging, and firefighting foam. Such extensive use has led to concerning levels of environmental contamination and reports of associations with a spectrum of negative health outcomes, including testicular cancer and reduced semen quality. To investigate the effects of PFAS on male reproduction, we incubated mouse sperm in a cocktail of nine PFAS at environmentally relevant concentrations before checking for a range of functional outcomes. This treatment strategy was not toxic to the sperm; it did not kill them or reduce their motility, nor did it affect their fertilization capacity. However, we did observe developmental delays among pre-implantation embryos created using PFAS-treated sperm. Such findings raise the intriguing prospect that PFAS-exposed sperm harbor a form of stress signal that they deliver to the embryo upon fertilization.
Orientación profesional para la efectiva inserción laboral del estudiantado de educación comercial, periodo 2017
Authors: España Chavarría Carolina , Arce Soto Fabian 
Published: February 2024

This qualitative descriptive study took up the challenge of analyzing the professional guidance for the effective labor insertion: of students from the commercial education major, term 2017. To achieve this purpose it was necessaryto diagnose the connection between vocational guidance and employability in the university level of education, as well as, to determine the added value that provides vocational guidance and working context acknowledgment forprofessional projection of the target group. Without a doubt, inputs obtained in this study served as the basis for rethinking training activities in the field of vocational guidance as job placement support.
Análisis de la relación que tiene la Planificación y la Ejecución Presupuestaria en las Municipalidades de Costa Rica
Authors: Armas Vallejos Gabael 
Published: February 2024

The objective of this study is to analyze the incidence that planning has on budget management in the municipalities of Costa Rica, given that they presentsome deficiencies such as: low-qualified human resources, planning problems, centralism in political and financial practices, and low budget execution.To achieve what was proposed, a descriptive investigation was carried out, taking as a reference the database of the Municipal Management Index 2018,of the Comptroller General of the Republic of Costa Rica.As a result, it is obtained that in the variable Obligations for financing, there is a positive relationship between compliance with the operating plan andbudget execution. Additionally, there is a positive relationship between the participatory budget and budget execution. Otherwise, the municipalities witha regulatory plan cause a negative effect of -8.99 on financing obligations.In the variable Investment in local projects, the municipalities that comply with the operational plan have a negative effect (-0.89%) on the investment in localprojects. There is also a negative relationship between the participatory budget (-0.89%) and budget execution. There is a positive relationship between theexistence of regulatory plans and budget execution, with a positive effect of 4.3% on investment in local projects.It is concluded that, , the operational plan and participatory budget compliance variables positively affect financing obligations, but in local project investments, both have a negative effect.
Identificación espacial del riesgo por deslizamiento de tierra en el municipio de Autlán de Navarro, Jalisco, México
Authors: González-Bolaños Fátima , Olguín-López José Luis , Palomera - García Carlos , Guevara-Gutiérrez Rubén Darío 
Published: February 2024

The municipality of Autlán presents problems of land use change and erosion that favor landslides. Spatial identification of these phenomena (5 risk classes) shows that 3 localities are located in high and very high risks areas (Autlán, Ahuacapán and Mezquitán), mainly due to the influence of Regosol soils, annual and maximum precipitation in 24 hours with a statistically significant relationship of P < 0.05, R2 = 0.99, 0.66 and 0.86. Landslides represent a risk for infrastructure and the population, finding a significant relationship (α = 0.001) between the number of houses and population density per locality only for regular to high threat to landslide. In the absence of land use planning by the municipality, attention and remediation activities are proposed, mainly in urban areas located in landslide-sensitive structures, taking into account the results obtained
Difusión Espacial de la Devoción a Toribio Romo por Migrantes Mexicanos a Estados Unidos
Authors: Medina Gallo César Eduardo 
Published: February 2024

The spatial diffusion of the devotion to Toribio Romo has intensified due to the migration of Mexicans to the United States. It will be discussed how, from the experience of mobility of believing migrants, the devotion to the saint extends to new territories and believers across different geographical scales, influenced by historical and socio-cultural contexts, which are reinforced and establish connections with their places of origin through religious practices and traditions through the image of Toribio Romo. To achieve this purpose, a bibliographical review of the spatial diffusion is presented to explain the expansion of the devotion.
Additionally, the expansion of the devotion between Mexico and the United States will be mapped through fieldwork conducted under the methodology of multi-sited ethnography.
Modificación del corredor aorto-psoas para el acceso oblicuo lumbar intervertebral según los cambios posturales y la composición corporal. Estudio multicéntrico observacional mediante resonancia magnética
Authors: De Zavalía Máximo , Gobbi Enrique , Mazzeo Juan J. , Verna Bruno , Lanari Zubiaur Felipe , Yeregui Santiago 
Published: February 2024

Introducción: La cirugía mínimamente invasiva de columna se ha vuelto cada vez más popular en los últimos años. Se han desarrollado técnicas nuevas y menos invasivas que se han convertido en procedimientos de elección para determinadas enfermedades. El tamaño del corredor aorto-psoas es un factor determinante al elegir la técnica oblicua de fusión intersomática.
Objetivos: Describir las modificaciones en el tamaño del corredor aorto-psoas en decúbito lateral derecho y decúbito supino mediante resonancia magnética y su asociación con el índice de masa corporal.
Materiales y Métodos: Se realizó una resonancia magnética de los espacios discales de L1-L2 a L4-L5 a 13 voluntarios en decúbito supino y decúbito lateral derecho. Se midió el corredor y se comparó el tamaño en cada nivel.
Resultados: El tamaño del corredor aorto-psoas y de la distancia arteria-disco tuvo un aumento estadísticamente significativo al posicionar al paciente en decúbito lateral derecho.
Conclusiones: La resonancia magnética es de suma importancia en la planificación prequirúrgica, pues deja en evidencia la movilidad de las estructuras abdominales. Se producen cambios significativos en el corredor aorto-psoas y la distancia arteria-disco al ubicar al paciente en decúbito lateral derecho. Sin embargo, estos cambios no tienen una relación significativa con el índice de masa corporal.
Manifestación clínica inicial de la lipomatosis epidural lumbar grado III de Naka: serie de casos
Authors: Erausquin Tomás Ignacio , Rosado Pardo José A. , Vital Jean Marc , Sarotto Aníbal José , Besse Micaela 
Published: February 2024

Introducción: La lipomatosis epidural espinal es una enfermedad infrecuente caracterizada por el sobrecrecimiento del tejido adiposo no encapsulado dentro del espacio epidural. Esto genera una estenosis del conducto espinal que puede provocar sintomatología compresiva. La presentación típica es insidiosa a lo largo de meses o años. El objetivo de este estudio fue realizar un análisis descriptivo de la manifestación clínica inicial en pacientes con lipomatosis epidural espinal grado III de Naka.
Materiales y Métodos: Estudio observacional retrospectivo en la Unidad de Patología Espinal de 4 instituciones, de 2010 a 2023. Se incluyó a pacientes >18 años, de ambos sexos, que acudieron por dolor lumbar con irradiación o sin irradiación, y presentaban lipomatosis lumbar Naka III en la resonancia magnética.
Resultados: Se incorporó a 40 pacientes (edad promedio 62.5 años). El 75% era obeso, ninguno era fumador. El motivo de consulta más frecuente fue lumbalgia, con una mediana de evolución del dolor de 5.5 meses.
Conclusiones: La lumbalgia fue la consulta más frecuente, con excepción del compromiso de L3-S1 que fue la lumbocruralgia. Los pacientes que sufrieron dolor más tiempo (>6 meses) eran más jóvenes y tenían un índice de masa corporal menor; sin embargo, no resultó estadísticamente significativo.
Frecuencia del dolor lumbar en médicos especialistas en Ortopedia y Traumatología: estudio transversal
Authors: Besse Micaela , Ricciardi Guillermo A. , Cubecino Adriana E. , Bulos Claudio E. , Rosado Pardo José A. , Ricciardi Daniel O. , Sarotto Aníbal J. 
Published: February 2024

Introducción: Hasta el 85% de la población padecerá, al menos, un episodio de dolor lumbar a lo largo de su vida. Representa una de las principales quejas del personal de salud, y tiene una prevalencia anual del 77%; los traumatólogos tenemos múltiples factores de riesgo para desarrollar este cuadro. El objetivo de este estudio fue evaluar la prevalencia de lumbalgia e identificar posibles factores asociados, en una muestra de médicos traumatólogos.
Materiales y Métodos: Estudio analítico observacional transversal sobre el padecimiento de dolor lumbar en médicos especialistas en Ortopedia y Traumatología, miembros de la AAOT. El cuestionario se envió semanalmente durante un mes.
Resultados: Se recibieron 393 respuestas, predominó el sexo masculino, y la media de la edad era de 46 años. Más del 50% de la muestra refirió sobrepeso, y el 43%, sedentarismo. La media de autopercepción de estrés laboral fue de 7. Un 86% afirmó haber sufrido, al menos, un episodio en el último año y un 38%, másde 4 episodios.
Conclusiones: La prevalencia de lumbalgia fue alta. Predominaron los episodios agudos, no fueron necesarios estudios complementarios. Menos del 10% hizo reposo laboral. El hábito sedentario, el número de comorbilidades y la edad se asociaron con un riesgo más alto de sufrir >2 episodios de dolor.
Tratamiento de las fracturas cervicales aisladas de tipo “masa lateral flotante”: serie de casos
Authors: Cirillo Juan Ignacio , Peña Esteban , Ricciardi Guillermo A. , Contreras Martín , Pons Belmonte Rodrigo , Vía Dorado José , Carazzo Charles , AO Spine América Latina Grupo de Estudio de Trauma 
Published: February 2024

Objetivo: Presentar una serie de casos de pacientes con fracturas cervicales de tipo “masa lateral flotante” con énfasis en describir el rol de la lesión discal en la potencial inestabilidad segmentaria.
Materiales y Métodos: Se realizó un estudio descriptivo y retrospectivo de una serie de pacientes con fracturas facetarias de tipo “masa lateral flotante”, aisladas, diagnosticadas entre el 1 de enero de 2016 y el 1 de enero de 2022. Se incluyeron pacientes con lesiones de tipo “masa lateral flotante” según la clasificación AO, diagnosticadas por tomografía computarizada y, al menos, 6 meses de seguimiento. Se excluyó a aquellos con fracturas patológicas, lesiones por fragilidad ósea y registros incompletos.
Resultados: Se analizó a 16 pacientes (media de la edad 42.86; DE 12,396), con predominio del sexo masculino (81,25%). El 68,75% tenía una lesión del disco intervertebral en el segmento fracturado y el 18,75%, anterolistesis. A 11 pacientes se les propuso un tratamiento conservador durante 12 semanas. La fractura consolidó en el 45,4% y 6 (54,6%) evolucionaron con traslación. El fracaso del tratamiento conservador se asoció con lesión del disco intervertebral. Once pacientes fueron operados, en su mayoría, con artrodesis cervical anterior monosegmentaria.
Conclusiones: En esta serie de casos, la presencia de una lesión asociada del disco intervertebral fue más frecuente cuando el tratamiento conservador fracasó y cuando se decidió una artrodesis como tratamiento inicial. La mayoría de las cirugías se realizaron por vía anterior con discectomía y artrodesis cervical anterior en un único nivel, y se lograron buenos resultados.
Efek Pemberian Positive End Expiratory Pressure 5 cmH2O terhadap Perubahan Nilai Forced Expiratory Volume in 1 Second dan Forced Vital Capacity pada Pasien Pascaoperasi Ortopedi
Authors: Dwikane Mohamad Rizki , Oktaliansah Ezra , Budipratama Dhany 
Published: February 2024

Prinsip lung protective ventilation merupakan strategi ventilasi intraoperasi yang direkomendasikan untuk mencegah komplikasi paru pascaoperasi. Penelitian ini bertujuan mengetahui efek pemberian PEEP 5 cmH2O terhadap nilai FEV1 dan FVC pada pasien pascaoperasi ortopedi. Penelitian dilakukan terhadap 54 pasien yang dibagi menjadi 2 kelompok, yaitu kelompok PEEP 5 dan kelompok kontrol (PEEP 0). Penelitian eksperimental ini menggunakan desain single-blind randomized controlled trial dan melibatkan 54 pasien yang dilakukan operasi ortopedi di RSUP Dr. Hasan Sadikin Bandung pada bulan Oktober 2021–Januari 2022. Analisis statistik menggunakan uji T tidak berpasangan dan Uji Mann-Whitney. Hasil penelitian ini menunjukkan bahwa pada kelompok PEEP 5 terjadi penurunan nilai FEV1 lebih rendah dengan rerata –0,17±0,123 dibanding dengan kelompok kontrol (PEEP 0) sebesar -0,49±0,237. Pada kelompok PEEP 5 terjadi penurunan nilai FVC yang lebih rendah dengan rerata -0,20±0,132 dibanding dengan kelompok kontrol (PEEP 0) sebesar -0,60±0,23. Terdapat perbedaan yang signifikan secara statistik antara kelompok PEEP 5 dan PEEP 0 (p<0,05). Simpulan penelitian ini adalah perubahan penurunan nilai FEV1 dan FVC pada pasien pascaoperasi ortopedi dengan pemberian PEEP 5 cmH2O lebih rendah dibanding dengan kelompok kontrol (PEEP 0). Effects of Positive End Expiratory Pressure cmH2O on Changes in Forced Expiratory Volume in 1 Second and Forced Vital Capacity Values in Post Orthopedic Surgery PatientsThe principle of protective lung ventilation is the recommended ventilation strategy to prevent postoperative pulmonary complications. This study aimed to determine the effect of Positive End Expiratory Pressure (PEEP) 5 cmH2O on Forced Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC) post orthopedic surgery patients. The study was conducted on 54 patients divided into two groups: the PEEP 5 group and the control group (PEEP 0). This experimental study used a single-blind randomized controlled trial design involving 54 patients undergoing orthopedic surgery at dr. Hasan Sadikin General Hospital Bandung between October 2021–January 2022. Statistical analysis was performed using the unpaired T-test and Mann-Whitney test. Study results revealed that in the PEEP 5 group, there was a smaller decrease of FEV1 values, with an average of -0.17±0.12 compared to the control group (PEEP 0) of -0.49±0.23. In the PEEP 5 group, there was a smaller decrease in the FVC value with an average of -0.20 ± 0.13 compared to the control group (PEEP 0) of -0.60±0.23. There was a statistically significant difference between the PEEP 5 and PEEP 0 groups with (p<0.05). This study concludes that the decrease in FEV1 and FVC values in post orthopedic surgery patients with PEEP 5 cmH2O is lower than the control group (PEEP 0).
Flexible neural probes: a review of the current advantages, drawbacks, and future demands
Authors: Pimenta Sara , Freitas João R. , Correia José H. 
Published: February 2024

AbstractBrain diseases affect millions of people and have a huge social and economic impact. The use of neural probes for studies in animals has been the main approach to increasing knowledge about neural network functioning. Ultimately, neuroscientists are trying to develop new and more effective therapeutic approaches to treating neurological disorders. The implementation of neural probes with multifunctionalities (electrical, optical, and fluidic interactions) has been increasing in the last few years, leading to the creation of devices with high temporal and spatial resolution. Increasing the applicability of, and elements integrated into, neural probes has also led to the necessity to create flexible interfaces, reducing neural tissue damage during probe implantation and increasing the quality of neural acquisition data. In this paper, we review the fabrication, characterization, and validation of several types of flexible neural probes, exploring the main advantages and drawbacks of these devices. Finally, future developments and applications are covered. Overall, this review aims to present the currently available flexible devices and future appropriate avenues for development as possible guidance for future engineered devices.
A escola comum como espaço formativo para a dupla professor e intérprete educacional de Libras
Authors: Camargo Daroque Samantha , Broglia Feitosa de Lacerda Cristina 
Published: February 2024

Para conseguir alcançar melhores resultados na educação de alunos surdos, professores e intérpretes de Libras se beneficiam de estudos sobre modos mais eficientes para organização conjunta das ações de ensino de estudantes surdos no Ensino Fundamental II. Assim, esta pesquisa pretende tratar da importância do espaço formativo na escola comum entre professor e intérprete educacional (IE) de Libras, partindo das discussões e análises nesse campo de pesquisa. De forma mediada e especializada, ampliando as possibilidades de instrução e desenvolvimento, faz-se necessário discutir sobre as necessidades formativas de professores e IEs, sobre os desafios vivenciados por eles no cotidiano da sala inclusiva e apontar as possibilidades de instrução em espaço formativo na escola. As reflexões serão permeadas pelo arcabouço teórico de expoentes da área da educação de surdos que se articulam com os princípios da abordagem histórico cultural propostos por Vigotski (2021), ampliando as possibilidades de instrução e desenvolvimento, pelas e nas relações sociais compartilhadas. Os resultados revelam encontros produtivos, que contribuíram com os profissionais para que pudessem repensar suas representações, suas experiências, suas práticas, de maneira individual e coletivamente, a fim de transformarem em ações mais efetivas o ensino de estudantes surdos.
PALAVRAS-CHAVE: Formação de professores. Formação de intérprete de Libras. Acessibilidade Comunicacional. Mediação. Educação de Surdos. Educação Especial.
Orientações para a construção de materiais digitais focados na estimulação da compreensão leitora em pessoas idosas da comunidade
Authors: Santana Schmidt Dhaiele , Cristine Hübner Lilian 
Published: February 2024

Atualmente, os celulares tornam-se um novo suporte de leitura, modificando a forma de as pessoas lerem e se relacionarem com os textos. Todas as faixas etárias buscam utilizar as novas tecnologias, incluindo-se as pessoas idosas, que buscam entretenimento e conhecimento. Nesse contexto, o presente artigo busca apresentar o desenvolvimento de um aplicativo voltado para a estimulação cognitiva por meio da linguagem, destacando-se as atividades de compreensão leitora. O artigo pretende igualmente fornecer subsídios para o desenvolvimento de tarefas linguísticas digitais no nível do texto, tanto para a pesquisa quanto para a clínica, incluindo o envelhecimento atípico; esses subsídios podem auxiliar tanto pesquisadores quando desenvolvedores de tarefas digitais. Baseando-se em estudos da compreensão leitora, do texto e da leitura digital no envelhecimento, foram desenvolvidas atividades na plataforma HTML5 Package (H5P). É apresentado o processo de desenvolvimento dos textos e das atividades interativas, assim como exemplos visuais das atividades e os cuidados tomados durante a criação – considerando o público de pessoas idosas e suas necessidades. Conclui-se que o uso de aplicativos voltados para a estimulação cognitiva por meio de tarefas linguísticas deve ser ampliado, pelo seu potencial para beneficiar pessoas idosas típicas e atípicas a ampliarem sua reserva cognitiva, mitigando os efeitos do envelhecimento no cérebro e oferecendo maior qualidade de vida.