bluuebunny/crossref_metadata_2025_split huggingface dataset:
THE EFFECTS OF MATERNAL OBESITY ON MATERNAL AND NEONATAL OUTCOMES IN WOMEN WITH GESTATIONAL DIABETES
Authors: Faraj Fatima , Mahmood Maryam , Muhammad Huda , Salih Jamal 
Published: December 2023

Background
Obesity and gestational diabetes mellitus (GDM) can interfere. Poorly controlled blood glucose can cause unfavourable maternal and neonatal outcomes.
Objectives
The study aims to know the effects of maternal obesity on maternal and neonatal outcomes in pregnant women with controlled GDM..
Patients and Methods
A prospective observational study was performed on 90 pregnant women with GDM admitted to Sulaimani Maternity Teaching Hospital from January 2020 to January 2021. Maternal and gestational ages, residencies, gravidity, and parity were recorded. In addition, maternal body mass index, depending on Rcog guidelines for blood glucose targets, mode of delivery, and maternal and neonatal complications were noted. Also, neonatal complications were documented, including Apgar score and body weight.
Results
Maternal ages were 34.2±6.4 years, ranging from 21 to 45. Most of them (92.3%) resided inside Sulaimani. None of the maternal outcomes had a significant association with their body weight (P-value >0.05). One woman in the obese group had intrauterine fetal death. All neonatal consequences were significantly associated with maternal body weight (P-value <0.05).
Conclusion
The current study did not find significant associations between maternal body weights with maternal outcomes in women with controlled GDM. However, at the same time, maternal obesity has significantly increased neonatal complications.
THE EFFECTS OF OBESITY ON THE ACTIVE PHASE OF THE FIRST STAGE OF LABOR
Authors: Mahmood Dekan , Khalil Rozhan 
Published: December 2023

Background
Obesity is carrying many pregnant women now a day and has many risks for complications. There is an association between body mass index and the progression of the active phase of first-stage labor.
Objectives
To estimate and detect obesity’s effect on the duration and progression of the active phase of labor and the outcomes of the deliveries, either by vaginal delivery or cesarean section.
Patients and Methods
A prospective observational cross-sectional study was designed and conducted at Sulaimani maternity teaching hospital in Sulaimani City. From 1st February 2020 to 1st February 2021, about labor study included the progression of 184 multiparous women (para1-4) with a single vertex presentation from (37+1 to 41+6) weeks of complete gestation. Either by spontaneous or induction labor (misoprostol or oxytocin). Between four groups, defined by body mass index according to the world health organization. Normal (n=88), over weight (n=3), obesity class 1(n=43), obesity class 2(n=50)
Results
A total of 184 patients were collected in this study. The mean ± SD (standard deviation) age/year of participants was (27, 49 ±5.54 SD) minimum age was 17 years, and the maximum age was 44 years. A high percentage of them (51.6%) were living in urban. About (27.2%) were classified as obesity class 2, which carries a high percentage of cases that ends by cesarean section C/S (n=9) 81.8%, with prolonged duration of active phase by mean (4.988) and standard deviation (1.9302) in comparison with other classes.
Conclusion
The duration of the active phase of labor, cesarean section rate, and the time for induction until the active phase of labor were increased by increasing body mass index.
Rapid Source Characterization of the 2023 Mw 6.8 Al Haouz, Morocco, Earthquake
Authors: Yeck William L. , Hatem Alexandra E. , Goldberg Dara E. , Barnhart William D. , Jobe Jessica A. Thompson , Shelly David R. , Villaseñor Antonio , Benz Harley M. , Earle Paul S. 
Published: December 2023

Abstract
The U.S. Geological Survey (USGS) National Earthquake Information Center (NEIC) estimates source characteristics of significant damaging earthquakes, aiming to place events within their seismotectonic framework. Contextualizing the 8 September 2023, Mw 6.8 Al Haouz, Morocco, earthquake is challenging, because it occurred in an enigmatic region of active surface faulting, and low seismicity yet produced significant damage and loss of life. Here, we present the rapid earthquake source products produced by the USGS NEIC, describing how the source model was derived using both seismic and geodetic observations. Our analysis indicates that the earthquake was the result of oblique-reverse faulting in the lower crust on either a steeply north-dipping fault or a moderately south-dipping fault. Finite-slip models using seismic and geodetic data reveal a compact source, with slip occurring at depths of 15–35 km. The causative fault is not apparent, because the rupture did not break the surface, and it is not possible to definitively attribute the earthquake to a known structure. The earthquake centroid depth of 25 km is noteworthy, because it shows slip extending beyond common estimates of seismogenic depth. This earthquake highlights that the seismogenic processes associated with mountain building in this wide plate boundary region are poorly understood.
Effect of the Prognostic Nutrition Index on Long-Term Outcomes in Unprotected Left Main Coronary Artery Revascularization
Authors: Güzel Tuncay , Avcı Eyüp , Kırış Tuncay , Arık Baran , Arslan Bayram , İldırımlı Kamran , Yıldırım Bünyamin , Argun Lokman , Demir Muhammed , Aktan Adem , Özbek Mehmet , Aslan Burhan , Gitmez Mesut , Karaçalılar Mehmet , Çakır Çayan , Kılıç Raif , Ertaş Faruk 
Published: December 2023

Objective The prognostic nutritional index (PNI) is a practical, applicable, prognostic scoring system. However, its clinical significance in unprotected left main coronary artery (ULMCA) patients undergoing percutaneous coronary intervention (PCI) has not yet been clarified. This study aimed to examine the relationship between malnutrition as assessed by PNI and major adverse cardiac events (MACE) in ULMCA patients undergoing PCI.Material and methods 185 patients who were hospitalized in our clinic underwent coronary angiography, had a critical LMCA lesion, and underwent angiography-guided PCI were included. The study population was divided into tertiles based on the PNI values. A high PNI (n=142) was defined as a value in the third tertile (≥ 34.0), and a low PNI (n=43) was defined as a value in the lower 2 tertiles (< 34.0). The primary endpoint was MACE.Results MACE and mortality rates in the low PNI group were significantly higher compared to the high PNI group (51 % vs. 30 %, p=0.009; 44 % vs. 20 %, p=0.002, respectively). High PNI (HR:1.902; 95 % CI:1.112-3.254; p=0.019), previous stroke (HR:3.025; 95 % CI:1.038-8.810; p=0.042) and SYNTAX score (HR:1.028; 95 % CI:1.004-1.057, p=0.023) were independent predictors of MACE in the multivariable cox regression analyzes.Conclusions In patients undergoing ULMCA PCI, nutritional status can be considered an indicator of MACE rates by evaluating the PNI score. This index can be used for risk classification.
Metabolic Blood Hormones in Young People With Electrocardiographic Signs of Ischemic Myocardial Changes
Authors: Stakhneva E. M. , Kuzminykh N. A. , Scherbakova L. V. , Kashtanova E. V. , Polonskaya Ya. V. , Shramko V. S. , Garbuzova (Striukova) E. V. , Sadovski E. V. , Ragino Yu. I. 
Published: December 2023

Aim To study changes in blood concentrations of metabolic hormones and adipocytokines in people aged 25-44 years with electrocardiographic (ECG) signs of ischemic changes in the myocardium.Material and methods This study was a part of a cross-sectional survey of a random sample of Novosibirsk population aged 25-44 years. The study included 1363 people divided into two groups: group 1, subjects with ECG signs of ischemic changes in the myocardium and group 2, subjects without ECG changes. Blood serum concentrations of adipocytokines and metabolic hormones were measured by multiplex assay on a Luminex MAGPIX flow-through fluorometer.Results The group with ECG signs of myocardial ischemia had higher blood concentrations of adiponectin, resistin, glucagon, and interleukin 6 (IL-6) than in the comparison group. A multivariate logistic regression analysis showed that the glucagon concentration was associated with the presence of ECG signs of myocardial ischemia (OR, 1.019; CI, 1.018-1.034; p=0.017).Conclusion In young people aged 25-44 years, higher blood concentrations of glucagon are associated with the presence of ECG signs of myocardial ischemia.
Retrospective Analysis of Lipid-Lowering and Antiplatelet Therapy Regimen by Clinical Decision Support Service Based on Real-World Data from Electronic Medical Records “Intellect 3 Study”
Authors: Benimetskaya K. S. , Provatorov S. I. , Ezhov  M. V. , Krivosheev Y. S. , Gavrilko A. D. , Uranov A. E. , Mikheenko I. L. , Kovalev E. A. , Ponomarenko A. V. , Shangina A. M. , Efremova Yu. E. , Kolmakova T. E. , Matveeva M. A. , Dolgusheva Yu. A. , Alekseeva I. A. , Osokina A. K. , Nozadze D. N. , Atyunina I. V. , Paleev F. N. , Meshkova M. A. , Sharapova Yu. A. , Losik D. V. 
Published: December 2023

Aim To evaluate prescription of lipid-lowering and antithrombotic therapy in clinical practice and to compare differences in recommendations using the clinical decision support service (CDSS).Material and methods Electronic medical records (EMR) of 300 patients from the Chazov National Medical Research Center of Cardiology, as well as from medical organizations controlled by the Department of Health of the Lipetsk Region and the Ministry of Health of the Voronezh Region, were analyzed for the period of August - December 2022, during the pilot implementation of CDSS. Retrospective information about the prescription of lipid-lowering and antithrombotic therapy from the EMR was compared with the CDSS guidelines under the expert supervision based on digitized clinical and laboratory profiles of patients. The study primary endpoint was a change in the initially prescribed lipid-lowering and / or antithrombotic therapy as per CDSS guidelines.ResultsOverall 292 patients were included in the final analysis; 46 (15.7 %) were from the primary prevention group and 246 (84.3 %) from the secondary prevention group. In group 1, the lipid-lowering therapy recommended by the CDSS differed by 50 % (p<0.001) from the baseline therapy recorded in the EMR. In the secondary prevention group, 78.9 % (p<0.001) differences were found in the lipid-lowering therapy recommended in the CDSS guidelines compared to the prescriptions in the EMR. In 76.8 % (p<0.001) of patients, antithrombotic therapy was significantly different from the baseline therapy in the EMR.Conclusion The use of CDSS may improve the practice of choosing lipid-lowering and antithrombotic therapy for prevention of cardiovascular complications.
The Correlation of Caries Risk Assessment with Oral Hygiene Index and Parent’s Education Level in Pesantren Mizanul Ulum Sanrobone
Authors: Arifin Fadil Abdillah , Febriany Mila , Ilmianti Ilmianti 
Published: December 2023

Attention must be given to the boarding school students' oral health status. There is a considerable probability that boarding school students' oral cavities are going to suffer a variety of problems, particularly when they live and stay away from their parent's supervision. Caries risk assessment is used to predict and prevent the development of caries. This study aims to determine the correlation between caries risk assessment with oral hygiene status and parents’ education level in Pesantren Mizanul Ulum Sanrobone. Dental examinations and interviews were conducted on 61 students using the Caries Risk Assessment (CRA) form and Oral Hygiene Index Simplified (OHI-S). The correlation between caries risk assessment and oral hygiene status and the education level of students' parents was assessed using the Spearman test. According to the statistical analysis findings, there was a 0.312 correlation coefficient (r) between the CRA and the OHI-S. Meanwhile, the parents of the students have an education level of -0.198. These results showed a correlation between caries risk assessment and oral hygiene status (OHI-S), and no correlation with the education level of students’ parents. According to these findings, students are more likely to get cavities if their oral hygiene is poor.
O coeficiente de majoração dos esforços globais finais, 𝜸𝒛: origem, evolução e tendências
Authors: Cruz José Marcílio Filgueiras , Cruz Lucas Cavalcanti , Souza Jean Flávio Da Silva , Tannuss Yussef Harun 
Published: December 2023

<p>Hoje, mais que nunca, a engenharia tem respondido as necessidades do homem moderno e possibilitado a construção de edifícios cada vez mais altos com estruturas tão econômicas quanto possível. Estes edifícios são projetados, via de regra, com muita altura nominal e/ou com grande esbeltez geométrica, tornando-os sensíveis aos efeitos das ações horizontais e sua produção de efeitos de segunda ordem de magnitude relevante para a estabilidade e capacidade resistiva da estrutura. Este fato confere, por si só, continuada importância ao estudo da instabilidade global, que já conta com dois parâmetros oficiais: o parâmetro de instabilidade e o coeficiente , desenvolvido no Brasil. O segundo deles, referido pela NBR 6118 de 2023 como Coeficiente Gama Z de avaliação da importância dos esforços de segunda ordem globais e a sua relação com o parâmetro alfa, numérica e conceitual, são os objetivos deste trabalho. Por esta razão, um levantamento detalhado da origem, da evolução e das tendências desse coeficiente é efetuado, destacando concordâncias e faltas de consenso, entre diversos autores e diferentes edições da NBR 6118, acerca de limites e hipóteses simplificadoras consideradas para o cálculo. Também é realizada, neste trabalho, uma reformulação das equações convencionais que relacionam e , considerando não a redução global de 70% da rigidez, mas sim as reduções mais específicas preconizadas na norma atual. Isto é feito de modo que se possa compreender, de forma mais clara, as potencialidades e as suas limitações, criando condições de torná-lo mais confiável e mais simples de ser calculado.</p>
INNOVATIVE EFFECTS OF ARTIFICIAL INTELLIGENCE ON TEACHER EDUCATION
Authors: Köprülü Fatma , Oyebimpe Adewole Oluwatosin , Başarı Şengül , Besim Ayhan Seçil 
Published: December 2023

The goal of this investigation was to see the impact of AI on teacher education. To have a better understanding of how it will impact teacher education in problem-solving, how it will aid in planning, and whether it will promote continuous learning in teacher education. The study allows instructors and students from tertiary institutions in The Turkish Republic of Northern Cyprus to express their views. Three primary research topics guided these investigations, and four semi-structured interview questions were developed to obtain thorough responses to these issues. The opinions of the participants were solicited in person. The findings showed that both students and lecturers were aware and comfortable with AI in educational systems, that AI has had significant effects on problem-solving in teacher education, and that AI is vital for facilitating planning in teacher education. Finally, it was emphasized that the application of AI in teacher education allows for continuous learning, which has benefits as well as drawbacks.
Prácticas sociales asociadas a las movilidades en pandemia
Authors: Otero Adriana María , Rodríguez María Daniela , González Rodrigo 
Published: December 2023

Los impactos expuestos en la pandemia en la estructura productiva acontecieron de manera diversa y diferencial. Ante ello nos preguntamos: ¿cómo se reconfigurarán los espacios-tiempo de las movilidades contem­poráneas a partir de la crisis del covid-19? Desde una perspectiva de la espacialidad y las prácticas sociales, ¿cómo se interpreta en forma sustantiva el turismo posvacuna? Para el abordaje de los interrogantes presen­tados, este trabajo se estructura de acuerdo con una caracterización de ese momento en términos de los cambios societales y su conexión con el fenómeno de la pandemia, luego se abordan los cambios de percepción de espacio-tiempo y la visibilización y actualización de históricas disputas aso­ciadas a la desigualdad.
En diálogo con lo anterior, se reflexiona sobre los procesos de desterritorialización y reterritorialización como parte de un continuum signado por un escenario de desigualdad, conflictos y reconfiguraciones manifiestas en los territorios contempo­ráneos. Por último, el escrito indaga el turismo posvacuna desde una perspectiva de la espacialidad y las prácticas sociales.
A formação inicial de professores de Ciências Naturais e educação inclusiva: caminhos já percorridos nas pesquisas
Authors: Reis Matheus dos Santos , Almeida Alex Souza , Souza Francisnaide dos Santos , Dias Viviane Borges 
Published: December 2023

A formação de professores apresenta-se como importante aspecto para a efetivação da educação inclusiva, pois são os docentes que trabalham a maior parte do tempo com os alunos em situação de inclusão. Destarte, a pesquisa objetivou investigar os trabalhos indexados no Portal de Periódicos da Capes e na plataforma Scientific Electronic Library Online (SciELO), que abordam a formação inicial de professores de Ciências Naturais e educação inclusiva, no período de 2008 a 2022, com o intuito de evidenciar as principais tendências relacionadas com esse campo de pesquisa. O estudo apresenta caráter qualitativo. Para o mapeamento dos trabalhos foi utilizada a ferramenta de busca das bases de dados selecionadas. A busca dos trabalhos se deu a partir da seguinte equação: (“Educação Inclusiva”) AND (“Formação de Professores”) AND (“Biologia” OR “Física” OR “Química”). Obtivemos como resultado um universo de 283 artigos, dos quais 11 atendiam aos critérios da pesquisa. Os dados foram organizados em três eixos temáticos: a) mapeamento da produção científica; b) o currículo da formação inicial de professores de Ciências Naturais e a educação inclusiva; c) concepções dos futuros professores sobre a educação inclusiva. Reconhecemos que os resultados e reflexões proporcionados limitam-se ao contexto desta investigação e às bases de dados onde foram realizadas as pesquisas. Acredita-se, No entanto, que a investigação busca contribuir para o melhor entendimento de como a área de formação de professores de Ciências Naturais se articula com a educação inclusiva.
Molecular-genetic pathways of hepatitis C virus regulation of the expression of cellular factors PREB and PLA2G4C, which play an important role in virus replication
Authors: Mishchenko E. L. , Makarova A. A. , Antropova E. A. , Venzel A. S. , Ivanisenko T. V. , Demenkov P. S. , Ivanisenko V. A. 
Published: December 2023

The participants of Hepatitis C virus (HCV) replication are both viral and host proteins. Therapeutic approaches based on activity inhibition of viral non-structural proteins NS3, NS5A, and NS5B are undergoing clinical trials. However, rapid mutation processes in the viral genome and acquisition of drug resistance to the existing drugs remain the main obstacles to fighting HCV. Identifying the host factors, exploring their role in HCV RNA replication, and studying viral effects on their expression is essential for understanding the mechanisms of viral replication and developing novel, effective curative approaches. It is known that the host factors PREB (prolactin regulatory element binding) and PLA2G4C (cytosolic phospholipase A2 gamma) are important for the functioning of the viral replicase complex and the formation of the platforms of HCV genome replication. The expression of PREB and PLA2G4C was significantly elevated in the presence of the HCV genome. However, the mechanisms of its regulation by HCV remain unknown. In this paper, using a text-mining technology provided by ANDSystem, we reconstructed and analyzed gene networks describing regulatory effects on the expression of PREB and PLA2G4C by HCV proteins. On the basis of the gene network analysis performed, we put forward hypotheses about the modulation of the host factors functions resulting from protein-protein interaction with HCV proteins. Among the viral proteins, NS3 showed the greatest number of regulatory linkages. We assumed that NS3 could inhibit the function of host transcription factor (TF) NOTCH1 by protein-protein interaction, leading to upregulation of PREB and PLA2G4C. Analysis of the gene networks and data on differential gene expression in HCV-infected cells allowed us to hypothesize further how HCV could regulate the expression of TFs, the binding sites of which are localized within PREB and PLA2G4C gene regions. The results obtained can be used for planning studies of the molecular-genetic mechanisms of viral-host interaction and searching for potential targets for anti-HCV therapy.
Civic budget and its role in the process of urban reconstruction - a case study of the city of Lodz
Authors: Ślebocka Magdalena , Kilanowski Artur 
Published: December 2023

The purpose of the article/hypothesis: The aim of the article is to assess the role and importance of the civic budget in a broader processes of reconstruction of the degraded urban fabric in the period 2016–2023. The article poses a research hypothesis that the civic budget, as an advanced form of social participation not limited to information or public consultation, is a tool supporting the implementation of revitalization processes undertaken in the city. The research questions were helpful in verifying the proposed hypothesis: 1) Does the civic budget support revitalization processes? 2) What types of projects submitted as part of the civic budget are included in revitalization measures? 3) How is the tool that the civic budget is in revitalization perceived by stakeholders and initiators of these processes?
Methodology: The research involved a literature review and an analysis of numerical data and information on revitalization projects that can be found in the civic budget of Lodz. The study also used an original survey questionnaire conducted among the residents.
Results of the research: It was found that the civic budget in Lodz contributed to the implementation of a number of revitalization projects. The high civic awareness of the residents and their knowledge of the needs of their surroundings make it possible to implement these projects in areas where the condition of the urban fabric is critical. Thanks to the civic budget, the city's residents have had and continue to have an opportunity to make changes in their immediate environment. They can realize the most important investments from the point of view of local needs.
A governança do turismo em fronteira internacional: políticas públicas e paradiplomacia no contexto da RILA
Authors: Silva Fabio Roberto Cordeiro da , Grechi Dores Cristina , Carneiro Camilo Pereira 
Published: December 2023

A Rota de Integração Latino-Americana (RILA), também conhecida como Rota Bioceânica, é uma iniciativa com o potencial de promover o desenvolvimento da zona de fronteira Brasil-Paraguai. Os idealizadores da RILA objetivam, desde o surgimento da proposta em 2006 (que seria oficializada em 2015), impulsionar a atividade logística, com vistas a aumentar as exportações de commodities (grãos, minérios e carnes) e, em segundo lugar, potencializar a atividade turística regional. Nesse sentido, este artigo visou analisar as potencialidades e obstáculos que envolvem a governança do turismo na fronteira entre Brasil e Paraguai, especificamente nas cidades gêmeas de Porto Murtinho (BR) e Carmelo Peralta (PY). Em relação à metodologia, o presente trabalho configura uma pesquisa qualitativa, pautada em análise bibliográfica e documental, sob uma ótica interdisciplinar, ancorada nos referenciais do Turismo e da Geografia Política. Os resultados teórico-empíricos correspondem a delimitação conceitual do que se configura a governança do turismo em territórios de fronteira internacional e na organização da matriz institucional que dará subsídio à compreensão da organização do turismo e de sua governança no território pesquisado. De forma complementar, foram elaborados mapas que demonstram a intersecção entre a principal política de desenvolvimento do turismo em Mato Grosso do Sul e a RILA.