bluuebunny/crossref_metadata_2025_split huggingface dataset:
Visual Knowledge Domain of Artificial Intelligence in Computed Tomography: A Review Based on Bibliometric Analysis
Authors: Zhu Kunshu , Shen Zefang , Wang Min , Jiang Lufang , Zhang Ye , Yang Tiantong , Zhang Haidong , Zhang Mengzhou 
Published: January 2024

Abstract
Artificial intelligence (AI)–assisted medical imaging technology is a new research area of great interest that has developed rapidly over the last decade. However, there has been no bibliometric analysis of published studies in this field. The present review focuses on AI-related studies on computed tomography imaging in the Web of Science database and uses CiteSpace and VOSviewer to generate a knowledge map and conduct the basic information analysis, co-word analysis, and co-citation analysis. A total of 7265 documents were included and the number of documents published had an overall upward trend. Scholars from the United States and China have made outstanding achievements, and there is a general lack of extensive cooperation in this field. In recent years, the research areas of great interest and difficulty have been the optimization and upgrading of algorithms, and the application of theoretical models to practical clinical applications. This review will help researchers understand the developments, research areas of great interest, and research frontiers in this field and provide reference and guidance for future studies.
Measurement of Neutrophil Extracellular Traps as a Biomarker for the Differential Diagnosis Between Antineutrophil Cytoplasmic Antibody–Positive Individuals With Antineutrophil Cytoplasmic Antibody–Associated Vasculitis and Nonautoimmune Diseases
Authors: Menezes Pâmella Indira da Silva Oliveira , Veras Flávio Protásio , Cunha Fernando de Queiroz , Silva Lucienir Maria da , Louzada-Júnior Paulo , Oliveira Renê Donizeti Ribeiro 
Published: January 2024

Background/Objective
Neutrophil extracellular traps (NETs) have a correlation with disease activity in antineutrophil cytoplasmic antibody (ANCA)–associated vasculitis (AAV). However, it is not known whether there is an association between NETs and the presence of ANCA in other diseases. This study aimed to assess the occurrence of NETs in individuals with ANCA and whether serum NET quantitation is capable of distinguishing them with regard to the diagnosis.

Methods
This was a cross-sectional, observational study. From the positive ANCA by indirect immunofluorescence, 94 individuals were divided into groups: AAV, infectious diseases, and neoplastic diseases. Healthy controls served for comparisons. Neutrophil extracellular traps were evaluated through the investigation of NET remnants, by detecting cell-free DNA bound to proteins such as histone, myeloperoxidase, and neutrophil elastase (NE).

Results
In patients with perinuclear ANCA (p-ANCA) the detection of NETs by NE was able to distinguish AAV from infection/neoplasia and healthy controls. Receiver operating characteristic curves for serum NETs by NE in patients with p-ANCA were drawn in 2 situations: AAV versus infection/neoplasia, showing a sensitivity of 0.65 and specificity of 0.84, with an area under the curve of 65%; and AAV versus controls, showing a sensitivity of 0.84 and a specificity of 0.88, with an area under the curve of 96%.

Conclusions
For p-ANCA–positive individuals, we found higher serum NETs detected by NE-DNA in those with chronic infectious and neoplastic diseases than in AAV individuals and healthy controls. This allows us to infer that the evaluation of serum NETs may be of value as a biomarker for differential diagnosis.
Comparison of the 68Ga-FAPI Versus 18F-FDG in Gastric Adenocarcinoma and Anthracosis-Associated Lymph Nodes: FAPI Unmasking False-Negatives and False-Positives
Authors: Babacan Gündüzalp Buğrahan , Öner Tamam Müge , Şengiz Erhan Selma , Şahin Mehmet Can , Acar Tayyar Merve Nur 
Published: January 2024

Abstract
A 73-year-old woman with poorly differentiated gastric adenocarcinoma was referred to 18F-FDG PET/CT for evaluation of the disease. FDG PET/CT showed intense uptake in the disseminated lymph nodes. However, there was no uptake in the primary tumoral lesion. Subsequently, 68Ga-FAPI-04 PET/CT was performed with the decision of the tumor board and demonstrated intense uptake in the tumoral lesion. However, there was low or no uptake in disseminated lymph nodes. Tru-cut biopsy results revealed that all the lymph nodes were associated with anthracosis.
18F-FDG PET/CT Findings of Ovarian Myxoid Chondrosarcoma
Authors: Ou Lei , Zhou Yue , Deng Hao , Chen XiaoLiang 
Published: January 2024

Abstract
Ovarian myxoid chondrosarcoma is a rare and aggressive tumor. We present 18F-FDG PET/CT findings of ovarian myxoid chondrosarcoma. The images not only demonstrated a pelvic mass with increased FDG uptake, but also a mass with increased FDG uptake in the right lower abdominal wall. Ovarian malignancy with abdominal wall metastases was suspected. An extraskeletal myxoid chondrosarcoma was diagnosed histopathologically after the mass excision.
Pattern of Bone Marrow Hypometabolism on 18F-FDG PET CT in Systemic Lupus Erythematous–Associated Aplastic Anemia
Authors: Dudek Alexandra , Riaz Saima , Priftakis Dimitrios , Bomanji Jamshed 
Published: January 2024

AbstractWe present the case of a 23-year-old woman with juvenile onset systemic lupus erythematous on a background of thrombotic thrombocytopenic purpura, who was referred for18F-FDG PET CT scan due to pyrexia of unknown origin with raised inflammatory markers, severe thrombocytopenia, and anemia. An interesting pattern of predominantly photopenic hypometabolic bone marrow activity was demonstrated on18F-FDG PET CT.
Cerebral and Muscular Metastases From Prostate Adenocarcinoma Initially Depicted by 177Lu-PSMA SPECT/CT
Authors: Al-Ibraheem Akram , Istatieh Feras , Abdlkadir Ahmed Saad , Shahait Mohammed , Khreish Fadi 
Published: January 2024

AbstractCerebral and muscular metastases from prostatic adenocarcinoma occur rarely. Patients who develop such metastatic pattern exhibit noticeable symptoms. Herein, we present a 68-year-old man diagnosed with metastatic castrate-resistant prostate cancer. The patient received multiple177Lu-PSMA cycles. After the last cycle, a posttreatment SPECT/CT suggested disease progression with uncommon metastatic pattern in the right temporal brain lobe and muscles.68Ga-PSMA PET/CT and brain MRI confirmed these findings. Surprisingly, the patient remained asymptomatic up until the conclusion of the follow-up, which lasted for 3 months. This case emphasizes the importance of posttreatment scintigraphic imaging when other biomarkers are inconclusive.
PSMA Avidity in the Heterotropic Ossification—An Incidental Finding on PSMA PET/CT
Authors: Jain Tarun Kumar , Vohra Mansha , Sharma Bhawani Shankar , Dhal Shikha , Sharma Lalit Mohan 
Published: January 2024

Abstract
The upregulations of prostate-specific membrane antigen (PSMA) antigen are used for the presence of prostate cancer. However, published literature shows incidentally detected PSMA uptake in various nonprostatic benign and malignant conditions, which led to questioning the specificity of PSMA-targeted PET. In present case, we highlighted the abnormal PSMA expression in the benign bone abnormality.
Calyceal Diverticulum Found Incidentally on 18F-FDG PET/CT Imaging
Authors: Kashiwagi Nobuo , Nakaya Yasuhiro , Yoshino Yutaro , Tatsumi Mitsuaki , Tomiyama Noriyuki 
Published: January 2024

Abstract
A 69-year-old man with pancreatic cancer underwent 18F-FDG PET/CT examination for tumor staging. The PET images showed a focal mass-like FDG accumulation in the left kidney mimicking malignancy, whereas simultaneous CT and fused PET/CT images suggested a cystic lesion. On subsequent MR examination, the lesion appeared cystic on T2-weighted, contrast-enhanced arterial phase, and contrast-enhanced venous phase images. In addition, excretory phase images showed filling contrast medium to the cystic cavity, leading to a diagnosis of calyceal diverticulum. This report suggests that the possibility of a calyceal diverticulum should be considered in cases with focal FDG accumulation in renal cystic lesions.
Metastatic Renal Cell Carcinoma in a Patient With Autosomal Dominant Polycystic Kidney Disease
Authors: Rumrill Wyatt M. , Ballard David H. 
Published: January 2024

Abstract
Autosomal dominant polycystic kidney disease (ADPKD) manifests as multiple cysts in the kidneys and liver but can also present with musculoskeletal and cardiovascular abnormalities. ADPKD patients are at increased risk for renal cell carcinoma development. We show the FDG PET/CT findings in a patient with renal cell carcinoma secondary to ADPKD and complicated by worsening pulmonary metastasis. The primary renal tumor shows intense FDG uptake despite no suspicious features with contrast CT.
Internal and external validation of an updated ICD-10-CA to AIS-2005 update 2008 algorithm
Authors: Tillmann Bourke W. , Guttman Matthew P. , Thakore Jaimini , Evans David C. , Nathens Avery B. , McMillan Jennifer , Gezer Recep , Phillips Andrea , Yanchar Natalie L. , Pequeno Priscila , Scales Damon C. , Pechlivanoglou Petros , Haas Barbara 
Published: January 2024

BACKGROUND
Administrative data are a powerful tool for population-level trauma research but lack the trauma-specific diagnostic and injury severity codes needed for risk-adjusted comparative analyses. The objective of this study was to validate an algorithm to derive Abbreviated Injury Scale (AIS-2005 update 2008) severity scores from Canadian International Classification of Diseases (ICD-10-CA) diagnostic codes in administrative data.

METHODS
This was a retrospective cohort study using data from the 2009 to 2017 Ontario Trauma Registry for the internal validation of the algorithm. This registry includes all patients treated at a trauma center who sustained a moderate or severe injury or were assessed by a trauma team. It contains both ICD-10-CA codes and injury scores assigned by expert abstractors. We used Cohen's kappa (𝜅) coefficient to compare AIS-2005 Update 2008 scores assigned by expert abstractors to those derived using the algorithm and the intraclass correlation coefficient to compare assigned and derived Injury Severity Scores. Sensitivity and specificity for detection of a severe injury (AIS score, ≥ 3) were then calculated. For the external validation of the algorithm, we used administration data to identify adults who either died in an emergency department or were admitted to hospital in Ontario secondary to a traumatic injury (2009–2017). Logistic regression was used to evaluate the discriminative ability and calibration of the algorithm.

RESULTS
Of 41,869 patients in the Ontario Trauma Registry, 41,793 (99.8%) had at least one diagnosis matched to the algorithm. Evaluation of AIS scores assigned by expert abstractors and those derived using the algorithm demonstrated a high degree of agreement in identification of patients with at least one severe injury (𝜅 = 0.75; 95% confidence interval [CI], 0.74–0.76). Likewise, algorithm-derived scores had a strong ability to rule in or out injury with AIS ≥ 3 (specificity, 78.5%; 95% CI, 77.7–79.4; sensitivity, 95.1; 95% CI, 94.8–95.3). There was strong correlation between expert abstractor-assigned and crosswalk-derived Injury Severity Score (intraclass correlation coefficient, 0.80; 95% CI, 0.80–0.81). Among the 130,542 patients identified using administrative data, the algorithm retained its discriminative properties.

CONCLUSION
Our ICD-10-CA to AIS-2005 update 2008 algorithm produces reliable estimates of injury severity and retains its discriminative properties with administrative data. Our findings suggest that this algorithm can be used for risk adjustment of injury outcomes when using population-based administrative data.

LEVEL OF EVIDENCE
Diagnostic Tests/Criteria; Level II.
Longitudinal study of immunity to SARS-CoV2 in Ocrelizumab-treated multiple sclerosis patients up to 2 years after COVID-19 vaccination
Authors: Kister Ilya , Curtin Ryan , Piquet Amanda L. , Borko Tyler , Pei Jinglan , Banbury Barbara L , Bacon Tamar E. , Kim Angie , Tuen Michael , Velmurugu Yogambigai , Nyovanie Samantha , Selva Sean , Samanovic Marie I. , Mulligan Mark J. , Patskovsky Yury , Priest Jessica , Cabatingan Mark , Winger Ryan C. , Krogsgaard Michelle , Silverman Gregg J. 
Published: January 2024

ABSTRACTObjectives1 To plot the trajectory of humoral and cellular immune responses to the primary (two-dose) COVID-19 mRNA series and the third/booster dose in B-cell-depleted multiple sclerosis (MS) patients up to 2 years post-vaccination; 2. to identify predictors of immune responses to vaccination; and 3. to assess the impact of intercurrent COVID-19 infections on SARS CoV-2-specific immunity.Methods60 Ocrelizumab-treated MS patients were enrolled from NYU (New York) and University of Colorado (Anschutz) MS Centers. Samples were collected pre-vaccination, and then 4, 12, 24, and 48 weeks post-primary series, and 4, 12, 24, and 48 weeks post-booster. Binding anti-Spike antibody responses were assessed with multiplex bead-based immunoassay (MBI) and electrochemiluminescence (Elecsys®, Roche Diagnostics), and neutralizing antibody responses with live-virus immunofluorescence-based microneutralization assay. Spike-specific cellular responses were assessed with IFNγ/IL-2 ELISpot (Invitrogen) and, in a subset, by sequencing complementary determining regions (CDR)-3 within T-cell receptors (Adaptive Biotechnologies). A linear mixed effect model was used to compare antibody and cytokine levels across time points. Multivariate analyses identified predictors of immune responses.ResultsThe primary vaccination induced an 11-208-fold increase in binding and neutralizing antibody levels and a 3-4-fold increase in IFNγ/IL-2 responses, followed by a modest decline in antibody but not cytokine responses. Booster dose induced a further 3-5-fold increase in binding antibodies and 4-5-fold increase in IFNγ/IL-2, which were maintained for up to 1 year. Infections had a variable impact on immunity.InterpretationHumoral and cellular benefits of COVID-19 vaccination in B-cell-depleted MS patients were sustained for up to 2 years when booster doses were administered.
WITHDRAWN: Comparative effectiveness of extended release naltrexone and sublingual buprenorphine for treatment of opioid use disorder among Medicaid patients
Authors: Ross Rachael K. , Nunes Edward V. , Olfson Mark , Shulman Matisyahu , Krawczyk Noa , Stuart Elizabeth A. , Rudolph Kara E. 
Published: January 2024

Withdrawal StatementThis version of the manuscript and associated files have been removed owing to concerns of data privacy. The paper has been published and is available at doi:10.1111/add.16630.
Maternal fluoxetine impairs synaptic transmission and plasticity in the medial prefrontal cortex and alters the structure and function of dorsal raphe nucleus neurons in offspring mice
Authors: Bobula Bartosz , Bąk Joanna , Kania Agnieszka , Siwiec Marcin , Kiełbiński Michał , Tokarski Krzysztof , Pałucha-Poniewiera Agnieszka , Hess Grzegorz 
Published: January 2024

AbstractSelective serotonin (5-HT) reuptake inhibitors (SSRIs) are a class of antidepressant drugs commonly prescribed to women during pregnancy and breastfeeding to treat depression. There is evidence that prenatal exposure to SSRIs may be associated with a higher risk of adverse cognitive outcomes and affective disorders in later life. In animal models, exposure to SSRIs during brain development results in behavioral alterations as well as structural abnormalities of cerebral cortical neurons. Little is known about the consequences of SSRI- induced excess of 5-HT during development on the brain serotonergic system itself. In this study, an SSRI - fluoxetine (FLX) - was administered to C57BL/6J mouse dams during pregnancy and lactation. We found that maternal FLX decreased field potentials, impaired long-term potentiation, facilitated induction of long-term depression and tended to increase the density of 5-HTergic fibers in the medial prefrontal cortex (mPFC) of female but not male adolescent offspring. These effects were accompanied by deteriorated performance in the temporal order memory task and reduced sucrose preference with no change in marble burying behavior in FLX-exposed female offspring. We also found that maternal FLX reduced the axodendritic tree complexity of 5-HT dorsal raphe nucleus (DRN) neurons in female but not male offspring. Whole-cell recordings demonstrated no changes in the excitability of DRN 5-HT neurons in FLX-exposed offspring of either sex. While no effects of maternal FLX on inhibitory postsynaptic currents (sIPSCs) in DRN neurons were found, we observed a significant influence of FLX exposure on kinetic characteristics of spontaneous excitatory postsynaptic currents (sEPSCs) in DRN neurons. Finally, we report that no changes in field potentials and synaptic plasticity were evident in the mPFC of the offspring after maternal exposure during pregnancy and lactation to a new antidepressant, vortioxetine. These findings show that in contrast to the mPFC, long-term consequences of maternal FLX exposure on the structure and function of DRN 5-HT neurons are mild and suggest a sex-dependent, distinct sensitivity of cortical and brainstem neurons to FLX exposure in early life. Regarding side effects on brain development, vortioxetine might be a safer alternative to FLX.
Repeated Hand Grip Strength is an Objective Marker for Disability and Severity of Key Symptoms in Post-COVID ME/CFS
Authors: Paffrath Anna , Kim Laura , Kedor Claudia , Stein Elisa , Rust Rebekka , Freitag Helma , Hoppmann Uta , Hanitsch Leif G , Bellmann-Strobl Judith , Wittke Kirsten , Scheibenbogen Carmen , Sotzny Franziska 
Published: January 2024

AbstractPost-COVID Syndrome (PCS) refers to a diverse array of symptoms that persist beyond 3 months of the acute phase of a SARS-CoV-2 infection. The most frequent symptom is fatigue, which can manifest both mentally and physically. In this study, handgrip strength (HGS) parameters were determined as an objective measure of muscle fatigue and fatigability. HGS parameters were correlated with other frequent symptoms among 144 female PCS patients suffering from fatigue, exertional intolerance, and cognitive impairment. Seventy-eight patients met the Canadian Consensus Criteria (CCC) for post-infectious myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). The severity of disability and key symptoms were evaluated utilizing self-reported questionnaires. Notably, patients diagnosed with ME/CFS exhibited a higher overall severity of symptoms, including lower physical function (p< 0.001), a greater degree of disability (p< 0.001), more severe fatigue (p< 0.001), post-exertional malaise (p< 0.001), and autonomic dysfunction (p= 0.004). While HGS was similarly impaired in both PCS and ME/CFS patients, the associations between HGS and the severity of symptoms and disability revealed striking differences. We observed significant correlations of HGS parameters with physical function across all patients, but with the key symptoms PEM, fatigue, cognitive impairment, and autonomic dysfunction in ME/CFS patients only. This points to a common mechanism for these symptoms in the ME/CFS subtype, distinct from that in other types of PCS. Further HGS provides an objective marker of disease severity in ME/CFS.
Common data environments in construction: state-of-the-art and challenges for practical implementation
Authors: Jaskula Klaudia , Kifokeris Dimosthenis , Papadonikolaki Eleni , Rovas Dimitrios 
Published: January 2024

Purpose
Information management workflow in building information modelling (BIM)-based collaboration is based on using a common data environment (CDE). The basic premise of a CDE is exposing all relevant data as a single source of truth and facilitating continuous collaboration between stakeholders. A multitude of tools can be used as a CDE, however, it is not clear how the tools are used or if they fulfil the users’ needs. Therefore, this paper aims to investigate current practices of using CDEs for information management during the whole built asset’s life cycle, through a state-of-the-art literature review and an empirical study.

Design/methodology/approach
Literature data is collected according to the PRISMA 2020 guideline for reporting systematic reviews. This paper includes 46 documents in the review and conduct a bibliometric and thematic analysis to identify the main challenges of digital information management. To understand the current practice and the views of the stakeholders using CDEs in their work, this paper used an empirical approach including semi-structured interviews with 15 BIM experts.

Findings
The results indicate that one of the major challenges of CDE adoption is project complexity and using multiple CDEs simultaneously leading to data accountability, transparency and reliability issues. To tackle those challenges, the use of novel technologies in CDE development such as blockchain could be further investigated.

Originality/value
The research explores the major challenges in the practical implementation of CDEs for information management. To the best of the authors’ knowledge, this is the first study on this topic combining a systematic literature review and fieldwork.
The contagious effect of bullying knowledge hiding: exploring the role of job stress and power values
Authors: Kmieciak Roman 
Published: January 2024

PurposeBullying knowledge hiding has been recently identified as a manifestation of knowledge hiding behavior. As a relatively new concept, it is still underexplored. Previous research has focused on the antecedents of bullying hiding. However, there is a lack of research on the negative consequences that bullying hiding may have on employees. This study aims to uncover the effects of supervisor bullying hiding on employees knowledge behavior. The study also aims to examine the moderating effect of power values and the mediating effect of job stress.Design/methodology/approachData were gathered in two waves from 444 employees with higher education in Poland. Data collection was conducted in July and August 2022. A general linear model mediation analysis with jamovi Advanced Mediation Models software was used to examine the hypotheses.FindingsThe results indicate that bullying knowledge hiding by supervisors triggers subordinates’ job stress and aggression in the form of bullying knowledge hiding toward co-workers. Contrary to expectations, job stress does not mediate the relationship between supervisor bullying hiding and subordinate bullying hiding toward co-workers. Power-dominance values, contrary to power-resources values, moderate the above relationship.Practical implicationsAs bullying hiding has significant potential to spread among organizational members, managers seeking to reduce it should check the personal values of job applicants and employees.Originality/valueBased on the behavioral contagion and frustration–aggression–displacement theories, to the best of the author’s knowledge, this study is the first to investigate the relationships between supervisor bullying hiding, job stress, power values and subordinate bullying hiding toward co-workers.