bluuebunny/crossref_metadata_2025_split huggingface dataset:
COVID-19-Impfung: Motivations- und Belastungsfaktoren – Eine
Querschnittserhebung bei Ärzt*innen und Medizinischen
Fachangestellten in Deutschland
Authors: Schütte Ann-Kathrin , Wattenberg-Karapinar Ivonne , Hornberg Claudia , Lätzsch Rebecca 
Published: October 2023

Zusammenfassung
Ziel Ziel der Studie war die Bereitstellung von Ergebnissen zu
Motivations- und Belastungsfaktoren bezogen auf die COVID-19-Impfkampagne bei
ambulanten Ärzt*innen und Medizinischen Fachangestellten (MFA)
in Deutschland.
Methodik Im Rahmen einer quantitativen, nicht-repräsentativen
Online-Erhebung wurden insgesamt 514 Ärzt*innen und MFA aus
unterschiedlichen oder der selben Praxis zu Teilnahmegründen und
-hindernissen an der Impfkampagne, organisatorischen Rahmenbedingungen –
auch bezogen auf Impfstofflieferungen und -verfügbarkeit – sowie
die Arbeitsbelastung befragt.
Ergebnisse 70,3% der Befragten waren Ärzt*innen
und 28,8% waren MFA. In beiden Berufsgruppen kommt die Mehrzahl aus
Nordrhein-Westfalen (insgesamt 73,7%). Hauptmotivationsgründe
für die Teilnahme an der Impfkampagne waren der Beitrag zur
Bekämpfung der Pandemie (92,3%) und das Vorantreiben der
Impfkampagne (90,1%). Bei 94,6% der Befragten war die
Arbeitsbelastung seit Beginn der Impfkampagne im April 2021 gestiegen. Zentrale
Belastungsfaktoren waren der erhöhte bürokratische Aufwand
(92,5%), die Terminvergabe für die Impfungen (91%),
Patient*innenanfragen (90,3%) und der
Mehraufwand/Überstunden (83%). Als Grund für die
Nichtteilnahme an der Impfkampagne wurde ein zu hoher bürokratischer
Aufwand (69,6%) am häufigsten genannt.
Schlussfolgerung Eine Vielzahl der Praxen leistet mit der Teilnahme an der
COVID-19-Impfkampagne einen zentralen Beitrag zur Bekämpfung der
Pandemie, damit verbunden ist jedoch auch eine hohe Belastungssituation. Die
Dynamik des Infektionsgeschehens sowie häufig veränderte
Anforderungen und politische Vorgaben an die impfenden Praxen verstärken
dies noch. Der Wunsch nach einem einheitlichen und weniger
bürokratischen Vorgehen ist groß.
Combination Foley Catheter–Oxytocin versus Oxytocin Alone following Preterm Premature Rupture of Membranes
Authors: Gomez Slagle Helen B. , Hoffman Matthew K. , Sciscione Anthony C. , Ma'ayeh Marwan 
Published: October 2023

Objective The benefit of mechanical ripening agents following preterm premature rupture of membranes (PPROM) has not been established. We sought to compare the time to delivery in women who received transcervical Foley catheter plus oxytocin infusion versus oxytocin infusion alone in patients with unfavorable cervices and PPROM.
Study Design This is a retrospective cohort study of patients presenting with PPROM of a live, singleton gestation between 240/7 and 366/7 weeks' gestation from January 2005 to October 2018 at a single, tertiary care institution. Patients with an unfavorable cervical examination (≤2-cm dilation), no contraindication to labor and undergoing labor induction were analyzed. Time to delivery was analyzed using multivariable linear regression adjusting for cervical dilation at induction and nulliparity. Bivariate and multivariate analyses were used where appropriate.
Results A total of 260 participants were included: 109 who received a Foley catheter and oxytocin (Foley/oxytocin) and 151 who had oxytocin alone. Demographic characteristics were similar between the two groups. Unadjusted time to delivery was significantly shorter in the oxytocin only group (Foley/oxytocin: 20.35 hours vs. oxytocin alone: 14.7 hours, p < 0.001). No differences in length of labor were detected after adjusting for cervical dilation at induction and nulliparity (p = 0.5). The unadjusted rate of cesarean delivery was higher in the combination Foley/oxytocin group (Foley/oxytocin: 16.5% vs. oxytocin alone: 7.3%, p = 0.03), but no differences were found in the adjusted analysis (p = 0.06). There were no differences in clinical chorioamnionitis rates between the two groups (Foley/oxytocin: 8.3% vs. oxytocin alone: 9.3%, p = 0.83). Furthermore, no significant differences were found in maternal and neonatal outcomes between the two groups.
Conclusion In patients with PROM, the use of a transcervical Foley catheter in addition to oxytocin is not associated with a shorter time to delivery compared with oxytocin alone.
Key Points
Delivery Outcomes and Postpartum Readmissions Associated with Ehlers–Danlos Syndrome
Authors: Wright Gillian L. , Wen Timothy , Engel David J. , Guglielminotti Jean , Andrikopoulou Maria , Booker Whitney A. , D'Alton Mary E. , Friedman Alexander M. 
Published: October 2023

Objective Given that updated estimates of Ehlers–Danlos syndrome and risks for obstetric complications including postpartum readmission may be of public health significance, we sought to analyze associated obstetric trends and outcomes in a nationally representative population.
Study Design The 2016 to 2020 Nationwide Readmissions Database was used for this retrospective cohort study. Delivery hospitalizations to women aged 15 to 54 with and without Ehlers–Danlos syndrome were identified. Temporal trends in Ehlers–Danlos syndrome diagnoses during delivery hospitalizations were analyzed using joinpoint regression to estimate the average annual percent change with 95% confidence intervals (CIs). To determine whether adverse obstetric outcomes during the delivery were associated with Ehlers–Danlos syndrome, unadjusted and adjusted logistic regression models were fit with unadjusted (odds ratio [OR]) and adjusted ORs with 95% CIs as measures of association. In addition to analyzing adverse delivery outcomes, risk for 60-day postpartum readmission was analyzed.
Results An estimated 18,214,542 delivery hospitalizations were included of which 7,378 (4.1 per 10,000) had an associated diagnosis of Ehlers–Danlos syndrome. Ehlers–Danlos syndrome diagnosis increased from 2.7 to 5.2 per 10,000 delivery hospitalization from 2016 to 2020 (average annual percent change increase of 16.1%, 95% CI: 9.4%, 23.1%). Ehlers–Danlos syndrome was associated with increased odds of nontransfusion severe maternal morbidity (OR: 1.84, 95% CI: 1.38, 2.45), cervical insufficiency (OR: 2.14, 95% CI: 1.46, 3.13), postpartum hemorrhage (OR: 1.41, 95% CI: 1.17, 1.68), cesarean delivery (OR: 1.26, 95% CI: 1.17, 1.36), and preterm delivery (OR: 1.35, 95% CI: 1.16, 1.56). Estimates for transfusion, placental abruption, and placenta previa did not differ significantly. Risk for 60-day postpartum readmission was 3.0% among deliveries with Ehlers–Danlos (OR: 1.76, 95% CI: 1.37, 2.25).
Conclusion Ehlers–Danlos syndrome diagnoses approximately doubled over the 5-year study period and was associated with a range of adverse obstetric outcomes and complications during delivery hospitalizations as well as risk for postpartum readmission.
Key Points
Pilot study of an endoluminal-suturing device as a treatment for patients with gastroesophageal reflux disease
Authors: Louis Hubert , Van Ouytsel Pauline , Leclercq Loulia , Houinsou Hans Mélina , Devière Jacques , Rio-Tinto Ricardo , Huberty Vincent 
Published: October 2023

Abstract
Background and study aims Endoscopic therapy is a promising
option for patients with gastroesophageal reflux disease (GERD). The aim of this study was to
assess safety and feasibility of the Endomina suturing platform as a treatment for
GERD.
Patients and methods This was a two-center study of patients with
chronic GERD symptoms that responded at least partially to proton pump inhibitors (PPIs).
Primary endpoints were to assess the safety of the procedure and persistence of the sutures.
Secondary endpoints were to assess esophageal pH-impedance and manometry parameters changes at
6 months, as well as GERD symptoms and PPI use up to 12 months of follow-up.
Results Fourteen patients were treated (13 males, mean of 43±12
years), with a mean number of three plications per patient. Thirteen, 10, and nine patients
were analyzed at 3, 6, and 12 months of follow-up, respectively. One device-related adverse
event occurred (loss of needle tip requiring endoscopic retrieval 1 week later). A mean of two
plications persisted at 3 and 12 months. A decrease in median acid exposure time and reflux
episodes was observed after the procedure. Mean Reflux Symptom Index and GERD-Health-Related
Quality of Life scores decreased during follow-up visits and 90% of the patients discontinued
PPI use at 1 year.
Conclusions Endoscopic full-thickness suturing of the
esophagogastric junction with the Endomina suturing platform is feasible, allowing persistence
of two-thirds of the plications, with promising results for decreasing reflux and improving
GERD symptoms.
Point of Care Ultrasound in Pediatric Surgery across the European Region—European Pediatric Surgery Association Endorsed Survey
Authors: Lindert Judith , Rolle Udo , Naidoo Gerlin 
Published: October 2023

Abstract
Introduction Our purpose was to assess the state of training, clinical practice, and barriers to use point-of-care ultrasound (POCUS) in pediatric surgery in Europe.
Methods An electronic survey was disseminated among European pediatric surgeons utilizing the European Pediatric Surgery Association network and other existing networks.
Results There were 186 respondents from 27 European countries and 7 non-European countries. In most countries (86.6%; N = 161), the initial ultrasound for acute admissions is performed by radiologists, with 1 to 6 hours turnover in 62.9% (N = 117) of urgent cases. Ultrasound by pediatric surgeons (point-of-care ultrasound/POCUS) is performed by 48.4% (N = 90) of respondents, with 29% (N = 54) using it at least once per week. The most common indications for POCUS include abdominal focused abdominal sonography in trauma (53.8%; N = 100), diagnosis of appendicitis (41.9%; N = 78), and intussusception (44.6%; N = 84). In malrotation-volvulus, 28.5% (N = 53) used ultrasound for its diagnosis, while 27.5% (N = 51) would not see an indication here. Training in POCUS occurred informally for 55.4% (N = 103) of participants, while 31.2% (N = 58) attended formal training courses. Almost all respondents wanted to attain further POCUS training (89.3%; N = 166), only 7% (N = 13) did not think this would be useful. For 73.1% (N = 136), POCUS is not currently part of the pediatric surgery training curriculum in their country. Perceived barriers to POCUS use include a lack of training opportunities (26.3% [N = 49]) and a paucity of portable ultrasound machines (17.8% [N = 33]).
Conclusion There is a wide spectrum of POCUS use in pediatric surgery across Europe. For those surgeons who practice POCUS, it is most used for the diagnosis of abdominal conditions. There are differing views among clinicians concerning the most useful applications of POCUS. The extent to which ultrasound is taught during pediatric surgery training differs substantially across European curricula.
Immunometabolic and Vascular Health Responses among High Endurance
Trained Subjects
Authors: Fonseca Henrique A.R. , Bittencourt Celia Regina , Monteiro Andrea Moreira , Fonseca Francisco Antonio , Sanches Lívia Rentas , Ferreira Carlos Eduardo dos Santos , Neto Antonio Martins Figueiredo , Gidlund Magnus , Izar Maria Cristina 
Published: October 2023

AbstractIn this study, we aimed to examine the impact of high endurance training on
vascular health parameters and immune-endocrine responses against modified
low-density lipoprotein (LDL) particles. This observational, cross-sectional
study included high endurance-trained and healthy non-trained subjects. Vascular
ultrasound was used to assess vascular health parameters based on carotid
intima-media thickness and endothelial function (flow-mediated dilation).
Enzyme-linked immunosorbent assays were used to measure interleukin (IL)-8 and
IL-10, autoantibody isotypes anti-oxidized LDL (oxLDL) and anti-apolipoprotein B
(ApoB-D) peptide. Plasma levels of the corticosterone and 17
α-hydroxyprogesterone hormones were analyzed by mass spectrometry. This
study enrolled 96 subjects, of whom 44 were high endurance trained and 52 were
healthy non-trained individuals. Smaller carotid intima-media thickness values
were observed in the high-endurance trained than in the healthy non-trained
males, while no differences were observed between female groups. Flow-mediated
dilation measurements did not differ by training or sex. The humoral immune
responses to IgG anti-oxLDL and IgM anti-ApoB-D autoantibodies showed an isotype
imbalance between the high-endurance trained and the non-trained groups.
Immunoendocrine parameters showed inverse correlations between 17
α-hydroxyprogesterone concentrations and carotid intima-media thickness
measurements. Direct correlations were found between IL-10 concentrations and
flow-mediated dilation measurements. Chronic high-endurance exercise modulates
immune-endocrine and vascular health parameters, in a sex-dependent manner.
An explorative qualitative study of cyberbullying and cyberstalking in a higher education community
Authors: Bussu Anna , Ashton Sally-Ann , Pulina Manuela , Mangiarulo Marta 
Published: October 2023

AbstractThe literature suggests an increased risk of cybervictimisation during the COVID-19 pandemic. This paper explores student and staff experiences in a higher education community as victims of cyberbullying and cyberstalking during the COVID-19 lockdowns. An online semi-structured questionnaire was administered to self-identified students and staff victims within a higher education context. By analysing victim responses, within a qualitative framework, this research identifies perceptions, impacts and support mechanisms. The findings offer insights for the development of effective practices and policies to mitigate risk factors and foster resilience. This research addresses the need for comprehensive understanding in the face of emerging digital challenges and future traumatic events.
Market orientation practices of Ethiopian seed producer cooperatives
Authors: Sisay Dawit Tsegaye , Verhees Frans J. H. M. , van Trijp Hans C. M. 
Published: October 2023

AbstractThe practices of market orientation are context-specific. This paper focuses on the concept and practices of market orientation in Ethiopian seed producer cooperatives (SPCs). Based on 44 semi-structured interviews with experts and practitioners (SPC leaders and member farmers), we identify key market orientation elements in the SPCs’ context. Market orientation criteria in the Ethiopian SPC context could meaningfully be grouped into five underlying dimensions: quality of produce, business organization, external orientation, value addition activities, and supplier access. The understanding of market orientation by practitioners, particularly by member farmers, is limited to quality seed production. There is considerable recognition among respondents of the importance of customer orientation in the SPC context. Information on produced seeds, market prices, and profits is considered important. Information on competitors, although recognized by experts as important, is not really gathered by SPCs. Experts believe that the SPC committees should be responsible for information dissemination, but in practice, there is also an important role for the SPC chairman personally. Market-oriented practices in SPCs contribute to increasing employment and productivity and ensuring food security. Policymakers should devise strategies to support SPCs in becoming more market-oriented and successful in their business ventures. Specific market orientation practices by SPCs are discussed in detail.
Digitalized grammatization and critical thinking: synthesizing Chinese Chan pedagogy and Bernard Stiegler’s negentropic knowledge
Authors: Wu Amiao 
Published: October 2023

AbstractThis paper attempts to initiate a dialogue between Bernard Stiegler’s theories and Chinese Chan philosophy for a new vision of critical thinking. Specifically, I argue that Chan way of teaching can be aligned with Stiegler’s emphasis on recovering negentropic potentials and maintaining a noetic awareness within the context of algorithmic life. First, I present Stiegler’s discussion of intergenerational relations in transmitting true knowledge and his concerns about the liquidation of cognitive capabilities among younger generations. Second, I show how Chan teaching via the koan system may open up a perspective for transmitting “noetic experiences” and accentuating young people’s critical faculties. Then, I examine “the ordinary mind” of Chan teaching and consider how it corresponds to Stiegler’s negentropic form of knowledge. Finally, I contend that fostering critical thinking is to encourage young people to engage in lived activities and liberate them from the entropic non-becoming of digitalized grammatization.
The influence of communication climate, organizational identification, and burnout on real estate agents’ turnover intention
Authors: Lee Chun-Chang , Zheng Yu-Ru , Yeh Wen-Chih , Yu Zheng 
Published: October 2023

AbstractThis study investigated the factors that affect the turnover intention of real estate agents by considering the impact of individual-level factors such as job stress, burnout, and salary level and team-level factors such as communication climate and organizational recognition. The parameters were evaluated using a hierarchical linear moderated mediation model. The survey subjects were real estate agents in Tainan City. A total of 870 questionnaires were distributed to 87 real estate agencies, and 615 questionnaires from 77 branches were collected. The questionnaires from four branches were excluded, as fewer than two questionnaires were collected, and an additional 57 questionnaires with missing responses were also excluded. A total of 558 questionnaires from 73 branches were included in the study. The overall response rate of questionnaires was 64.1%. The results indicated that the greater a real estate agent’s awareness of the communication climate, the higher the likelihood of the real estate agent receiving recognition from their organization, while a higher salary level indicated a lower level of turnover intention. A greater understanding of job stress indicated a higher risk of burnout. The communication climate had an impact on burnout and turnover intention, while organizational recognition mediated the impact of communication climate as it pertained to turnover intention. The results showed that the level of burnout mediated the impact of job stress and turnover intention.
Stable high repetition-rate laser-driven proton beam production for multidisciplinary applications on the advanced laser light source ion beamline
Authors: Catrix Elias , Boivin Frédéric , Langlois Kassandra , Vallières Simon , Boynukara Canan Yağmur , Fourmaux Sylvain , Antici Patrizio 
Published: October 2023

Laser-driven proton accelerators are relevant candidates for many applications such as material science or medicine. Today, there are multi-hundred-TW table-top laser systems that can generate relativistic peak intensities &gt;1018 W/cm2 and routinely reach proton energies in the MeV range. However, for most desired applications, there is still a need to optimize the quality and stability of the laser-generated proton beam. In this work, we developed a 0.625 Hz high repetition-rate setup in which a laser with 2.5% RMS energy stability is irradiating a solid target with an intensity of 1019 to 1020 W/cm2 to explore proton energy and yield variations, both with high shot statistics (up to about 400 laser shots) and using different interaction targets. Investigating the above-mentioned parameters is important for applications that rely on specific parts of the proton spectrum or a high ion flux produced over quick multi-shot irradiation. We demonstrate that the use of a stable “multi-shot mode” allows improving applications, e.g., in the detection of trace elements using laser-driven particle-induced x-ray emission.
Physical properties with high specific loss power of magnetite (Fe3O4) synthesized via thermal decomposition technique
Authors: Uddin Md Kamal , Deb Nandita , Rashid Rimi , Das Harinarayan , Syed Ishtiaque M. , Hoque Sheikh Manjura 
Published: October 2023

Magnetic iron oxide nanoparticles have versatile applications in biomedical science that require control over shape and size distribution. Thermal decomposition is one of the best methods for controlling the size and shape of produced nanoparticles (NPs). The size distribution can be tuned (5–30 nm) by varying the reaction environment such as precursor concentration, amount of solvent used, temperature ramp, and reflux time. Iron oleate was used as a precursor solution and heated up to reflux temperature (310 °C) for 10 min within the oxygen-free environment by applying N2 gas flow. The XRD pattern confirmed the formation of NPs with a crystallite size of 17 ± 2.45 nm. Transmission electron microscope images showed moderately cubic shapes with a mean particle size of 28.67 ± 7.12 nm. Magnetic properties such as saturation magnetization, coercivity, and remanence were calculated at 23.48 emu/gm, 33 Oe, and 0.6 emu/gm, respectively, which indicated the ferromagnetic nature of the NPs. The Verwey transition was identified from the magnetization vs temperature (FC-ZFC) plot. The bondings of the oleic acid surfactant with the produced NPs were confirmed from Fourier transformation infrared spectroscopy (FTIR) data analysis. For the application of hyperthermia, the hydrophobic phase was transferred to the hydrophilic phase using cetyltrimethylammonium bromide, which was assured by the FTIR data analysis. The hyperthermia heating of NPs was measured for different concentrations of NPs (0.25, 0.5, 1, 2, and 4 mg/ml), from which specific loss power (SLP) was calculated. Among them, 0.25 mg/ml produced the most prominent SLP (2149 ± 309 w/g) that can be applied for targeted cancer treatment.
Characterizing the origin band spectrum of isoquinoline with resonance enhanced multiphoton ionization and electronic structure calculations
Authors: Krogmeier Timothy J. , Pappas Emerson S. , Reardon Kylie A. , Rivera Marcos R. , Head-Marsden Kade , Parsons Bradley F. , Schlimgen Anthony W. 
Published: October 2023

We report the experimental resonance enhanced multiphoton ionization spectrum of isoquinoline between 315 and 310 nm, along with correlated electronic structure calculations on the ground and excited states of this species. This spectral region spans the origin transitions to a π–π* excited state, which previous work has suggested to be vibronically coupled with a lower lying singlet n–π* state. Our computational results corroborate previous density functional theory calculations that predict the vertical excitation energy for the n–π* state to be higher than the π–π* state; however, we find an increase in the C–N–C angle brings the n–π* state below the energy of the π–π* state. The calculations find two out-of-plane vibrational modes of the n–π* state, which may be brought into near resonance with the π–π* state as the C–N–C bond angle increases. Therefore, the C–N–C bond angle may be important in activating vibronic coupling between the states. We fit the experimental rotational contour with a genetic algorithm to determine the excited state rotational constants and orientation of the transition dipole moment. The fits show a mostly in-plane polarized transition, and the projection of the transition dipole moment in the a-b plane is about 84° away from the a axis. These results are consistent with the prediction of our electronic structure calculations for the transition dipole moment of the π–π* excited state.