bluuebunny/crossref_metadata_2025_split huggingface dataset:
Effects of formal mentoring support onnewcomer–protégéaffective organizational commitment: aself‐concept‐based perspective
Authors: Birtch Thomas A. , Cai Zhenyao , Chiang Flora F. T. 
Published: October 2023

AbstractThe study proposes and tests a self‐concept‐based perspective for the effects of formal mentoring support on affective organizational commitment (AOC) via multiple mediators. Using time‐lagged multi‐source dyadic data (n = 203), we demonstrate that formal mentoring support significantly influences newcomer–protégés' AOC through an underlying self‐evaluative mechanism indicated by organization‐based self‐esteem (OBSE), even in the presence of a well‐established alternative mediator (perceived organizational support; POS). Moreover, we further demonstrate when or under what circumstances such effects might be attenuated or exaggerated by introducing a salient boundary condition to such a process (i.e., perceived mentor organizational prototypicality). As the findings reveal, by making newcomer–protégés feel good about themselves in the workplace (i.e., perceive self‐value) formal mentoring support can also promote organizational commitment, effects that are likely to be amplified when the formal mentor is perceived to be prototypical of the organization. Thus, bridging the mentoring and socialization literatures, the inclusion of our proposed mediators and moderator and testing their relationships simultaneously not only provides a more nuanced view of the underlying mechanisms through which the effects of formal mentoring support are channeled to influence newcomer–protégés' work attitudes but it offers new theoretical elaboration and contextual understanding that we hope will prompt future research and be of benefit to human resource practitioners. Implications to theory, practice and future research directions are discussed.
Differences in time to patient access to innovative cancer medicines in six European countries
Authors: Vancoppenolle Julie M. , Franzen Nora , Koole Simone N. , Retèl Valesca P. , van Harten Wim H. 
Published: October 2023

AbstractPatients across Europe face inequity regarding access to anticancer medicines. While access is typically evaluated through reimbursement status or sales data, patients can receive first access through early access programs (EAPs) or off‐label use. This study aims to assess the time to patient access at the hospital level, considering different indications and countries. (Pre‐)registered access to six innovative medicines (Olaparib, Niraparib, Ipilimumab, Osimeritinib, Nivolumab and Ibritunib) was measured using a cross‐sectional survey. First patient access to medicines and indications were collected using the hospital databases. Nineteen hospitals from Hungary, Italy, the Netherlands, Belgium, Switzerland and France participated. Analysis showed that some hospitals achieved patient access before national reimbursement, primarily through EAPs. The average time from EMA‐approval to patient access for these medicines was 2.1 years (Range: −0.9‐7.1 years). Hospitals in Italy and France had faster access compared to Hungary and Belgium. Variation was also found within countries, with specialized hospitals (x̄: −0.9 years; SD: 2.0) more likely to provide patient access prior to national reimbursement than general hospitals (x̄: 0.4 years; SD: 2.9). Contextual differences were observed, with EAPs or off‐label use being more prevalent in Switzerland than Hungary. Recent EMA‐approved indications and drug combinations reached patients at a later stage. Substantial variation in patient access time was observed between and within countries. Improving pricing and reimbursement timelines, fostering collaboration between national health authorities and market authorization holders, and implementing nationally harmonized, data‐generating EAPs can enhance timely and equitable patient access to innovative cancer treatments in Europe.
Range and variability of CBF in young adults: PC‐MRI and ASL studies
Authors: Su Feng‐Yi , Peng Shin‐Lei 
Published: October 2023

AbstractSeveral studies have compared phase contrast magnetic resonance imaging (PC‐MRI) with arterial spin labeling (ASL) in the same cohort of subjects. However, these earlier comparisons included subjects across a wide age range, which can contribute to increased intersubject variability. We compared the range and variability of CBF based on PC‐MRI and ASL in a group of young subjects. We also explored whether the comparison between PC‐MRI and ASL was dependent on sex. Thirty young subjects (17 females) were recruited in this study. The CBF from PC‐MRI (CBFPC) was calculated as the total blood flow normalized to brain parenchyma mass. The CBF from ASL (CBFASL) was quantified based on the perfusion kinetic model. The ratio between CBFASL and CBFPC was calculated. Females exhibited significantly higher CBF using both PC‐MRI (p < 0.05) and ASL (p < 0.005) compared with males. The disparity in CBF between sexes was more prominent in ASL measurements. A significant correlation was observed between CBFPC and CBFASL values (r = 0.47, p < 0.01), and CBFASL tended to be lower than CBFPC values (p < 0.001). This difference between CBFASL and CBFPC was more pronounced in males, as evidenced by the smaller CBFASL/CBFPC ratio in males (p < 0.05). The measurement of global CBF with PC‐MRI and ASL are correlated, but CBFASL exhibits lower values than CBFPC. As the underestimation of CBFASL is prominent in males, ASL amplifies the sexual dimorphism in CBF compared with PC‐MRI.
E‐trading and services quality effects on stock exchange in a developing country: A study of Dhaka stock exchange
Authors: Hoque Shah Md Safiul , Magd Hesham , Ashraf Mohammad , Osman Abu Zafar Md Rashed , Hoque Shah Mohammad Mazeedul 
Published: October 2023

AbstractIn a developing country like Bangladesh, Members' satisfaction with stock exchanges was examined in this study based on the quality of e‐trading services. Five specific objectives were set to accomplish the main objective. This study further used a tangibility dimension, empathy factor, and responsiveness dimension to define E‐trading service quality. We conducted a descriptive and explanatory survey with 192 participants and 186 respondents (96.8%). The research design consisted of a mix of descriptive and explanatory methods. Data were collected through survey questionnaires with Likert scales using the SPSS (version 25) software program. Data analysis and interpretation were carried out using both descriptive and inferential statistics. It was found that both the Dhaka e‐trading center and stock exchange moderately practiced all study variables. The level of member satisfaction with stock exchange services is significantly influenced by the level of reliability, tangibility, empathy, assurance, and responsiveness of that service. Using regression analysis, it has been found that the dimensions of E‐trading service quality can explain 57.5% of the variation in stock exchange members' satisfaction. There is a positive statistically significant relationship between members' satisfaction with reliability, assurance, tangibility, and empathy, and no statistically significant relationship between members' satisfaction with responsiveness. Thus, exchange management bodies should improve practices regarding these dimensions of E‐trading service quality to increase member satisfaction.
Farm‐level evaluation of area‐ and agroclimatic‐based index insurance
Authors: Tsiboe Francis , Tack Jesse , Yu Jisang 
Published: October 2023

AbstractWe utilize over 190,000 historical farm‐level dryland row‐crop yield observations (corn, sorghum, soybeans, and winter wheat) spanning over 7000 Kansas farms from 1973 to 2018 coupled with agroclimatic variables to assess the performance of a broad range of weather‐ and area‐based insurance products. Results showed substantial levels of basis risk across agroclimatic‐based indices, limited ability to reduce income variability under fair pricing, and underperformance relative to area‐based yield products. Growth‐stage specific heat indices for corn and soybeans may offer an effective risk management tool. Implications in the context of current agricultural policy initiatives and climate change adaptation are discussed.
Renal stiffness measured by shear wave elastography and its relationship with perirenal fat in patients with chronic kidney disease
Authors: Li Yiming , Liu Yongzhan , Gao Lili , Tian Chuan 
Published: October 2023

AbstractPurposeThis study aimed to utilize shear wave elastography (SWE) to assess changes in renal stiffness and its influencing factors in patients with chronic kidney disease (CKD) across different estimated glomerular filtration rate (eGFR) categories. It also sought to determine the correlation between perirenal fat (PF) and renal stiffness at various stages of CKD.MethodsA total of 190 CKD patients and 50 healthy controls were evaluated. Clinical parameters, conventional renal ultrasound measurements, PF, and renal stiffness trends were assessed separately. Factors independently associated with renal stiffness and PF were further analyzed.ResultsRenal parenchymal stiffness was significantly higher in the Albumin‐CKD G1‐2 (ALB‐CKD G1‐2) and CKD G3 groups than in the control group (p < 0.05). The parenchymal stiffness of the CKD G3 group was higher than that of the ALB‐CKD G1‐2 group (p < 0.05). The independent factors of renal parenchymal stiffness varied at different stages of disease development, with eGFR and PF being significant factors in the CKD G3 group. PF was elevated in the ALB‐CKD G1‐2 and CKD G3 groups compared to the control group, and the independent factors of PF varied across different stages, although waist circumference remained a common factor.ConclusionUsing SWE to detect renal elastic moduli can effectively assess changes in renal stiffness in patients with CKD with varying eGFRs. PF is an independent factor of renal stiffness in patients with CKD G3, providing a foundation for early diagnosis and clinical treatment.
Cancer patients' experience of receiving variant of uncertain significance results: An Asian perspective
Authors: Ishak Nur Diana , Shaw Tarryn , Li Shao‐Tzu , Yuen Jeanette , Goh Hui Xuan , Chua Zi Yang , Suresh Priyadharshini , Que Frances Victoria F. , Zhang Zewen , Chiang Jianbang , Ngeow Joanne 
Published: October 2023

AbstractDue to a lack of ancestry‐matched, functional, and segregation data, Asians have a higher rate of receiving a variant of uncertain significance (VUS) result following panel testing. Managing VUS results presents challenges, as it often leads to increased anxiety and distress among cancer patients undergoing genetic testing. This exploratory study aims to investigate the experience of Asian cancer patients upon receiving a VUS result. A qualitative, semi‐structured interview study was conducted, involving cancer patients who had received a VUS result through the Cancer Genetics Service of the National Cancer Centre Singapore. Twenty participants were interviewed, and their responses were transcribed and analyzed using thematic analysis to identify key themes. Thematic analysis revealed five major themes: (1) VUS results are interpreted as uncertain outcomes; (2) a VUS result provides relief and prompts positive behavioral adjustments; (3) patients employ fatalism and religion as coping mechanisms to navigate uncertainty; (4) genetic counselors, family, and the community offer reassurance and support; (5) patients value updates on variant classifications for future management. While this novel study provides unique insights into the perspectives of Asian patients who receive VUS results, it also highlights patients' effective management of VUS results and uncertainty, which has implications for improving counseling practices in Asia. Emphasis must be placed on accurate interpretation and clear communication of VUS results to dispel the possibility of misconceptions, misdiagnosis, and mismanagement in cancer care.
Characteristics of right pulmonary vein with an epicardial connection needing additional carina ablation for isolation
Authors: Nehashi Takeshi , Kaneshiro Takashi , Nodera Minoru , Yamada Shinya , Takeishi Yasuchika 
Published: October 2023

AbstractBackgroundThis study thought to elucidate the anatomical features that can predict an epicardial connection (EC) between the right pulmonary vein (RPV) and right atrium.MethodsWe retrospectively analyzed 251 consecutive patients undergoing initial radiofrequency pulmonary vein isolation. We defined EC as present when RPV could not be isolated with circumferential ablation and additional ablation for the conduction gap if needed, and RPV isolation could be achieved by ablation for the earliest activation site >10 mm inside the initial ablation line. Using computed tomography data, we evaluated the RPV bifurcation angle, and the area occupation ratio of the carina region to the RPV antrum (ARC) for predicting EC. In subjects with EC undergoing RPV activation mapping after circumferential ablation, the correlation between conduction delay and bipolar/unipolar potential voltage in the carina region was investigated.ResultsThere were ECs in 45 out of 251 patients (17.9%). The RPV bifurcation angle (47.7° vs. 38.8°, p < .001) and ARC (37.2% vs. 29.7%, p < .001) were significantly greater in the EC (+) group. Multivariate logistic regression analysis revealed that RPV bifurcation angle (odds ratio [OR]: 1.994, p = .002) and ARC (OR: 3.490, p = .013) were independent predictors of EC. In nine patients with EC undergoing carina region mapping, the unipolar potential voltage was correlated with conduction delay in RPV with EC (R = −0.401, p < .001).ConclusionAnatomical features suggesting a wider RPV carina region could predict the presence of EC, and potential with high voltage could be helpful for detecting EC connection sites.
Fog analysis of airports in the northeast of Turkey in the last decade
Authors: Uğurluel Gülneşe , Deniz Ali , Özdemir Emrah Tuncay 
Published: October 2023

AbstractFog is one of the important meteorological phenomena that play a critical role in the aircraft flying conditions and at airports. Fog events can lead to serious damage to the airport operations and the economy due to low visibility conditions and interrupting transportation. This study aims to explain the characteristics of the fogs occurring at the airports of the Kars, Agrı, and Igdır cities where located in the northeast of Turkey and neighbouring Georgia, Armenia, Nakhchivan, and Iran, and evaluate fog types. Within the scope of the study, a total of 3792 foggy aviation routine weather reports (METAR) and selected aviation special weather reports (SPECI) observations of the 10 years; from 2011 to 2020 were used for Igdır Şehit Bülent Aydın Airport (International Civil Aviation Organization [ICAO] code: LTCT), Kars Harakani Airport (LTCF) and Agrı Ahmed‐i Hani Airport (LTCO). During the time period studied, the number of foggy days in LTCT, LTCF, and LTCO was 41, 296, and 464, respectively. Fog events were most frequent from November to March, with December, January, and February being the most active months. August and September have no fog events in all three airports. Fog formation occurs usually at night hours and reaches a maximum around sunrise. Based on the physical formation mechanism, in LTCT, precipitation fog (PCP) was dominant at 39.02%; in LTCF and LTCO, radiation fog (RAD) was dominant at 33.11% and 58.84%, respectively.
Compound wind and precipitation extremes at a global scale based on CMIP6 models: Evaluation, projection and uncertainty
Authors: Zhu Xiaoyu , Yang Yi , Tang Jianping 
Published: October 2023

AbstractCompound wind and precipitation extremes (CWPEs) amplify risk to human health, socio‐economic and ecological systems relative to their single extreme meteorological events. Given the rise in weather and climate extremes resulting from global warming, it is crucial to evaluate the ability of the Coupled Model Intercomparison Project Phase 6 (CMIP6) models to capture this bivariate compound event and explore projected changes of CWPEs in the future under different climate‐change scenarios—the Shared Socioeconomic Pathway (SSP) scenarios. In this study, we first evaluate 14 CMIP6 models at a global scale using the ERA5 reanalysis data set spanning 1979–2014. Overall, some of the CMIP6 models, especially the multi‐model ensemble mean (MMEM), can reasonably capture CWPEs during the historical period, with more CWPEs in the northern and southern hemispheres during their respective cold seasons. However, the MMEM tends to overestimate CWPEs in some land areas and show underestimation in some oceanic regions. Then we compute projected changes of CWPEs in periods 1 (2041–2070) and 2 (2071–2100) under SSP1‐2.6, SSP2‐4.5 and SSP5‐8.5 scenarios. Low emission scenarios effectively mitigate the long‐term increase in future CWPEs. The occurrence of CWPEs will change significantly with the increase of emissions during period 2, particularly in polar regions. Finally, we quantify the uncertainty for global future projections of CWPE changes. The main sources of uncertainty are internal variability and model uncertainty, but the contribution of scenario uncertainty will increase as time progresses. Overall, our results provide useful information to cope with CWPEs' global impact, emphasizing the importance of incorporating the compound nature of weather and climate extremes in future climate projections.
Impact of southern annular mode on the Indian Ocean surface waves
Authors: Sreejith Meenakshi , Remya P. G. , Praveen Kumar B. , Srinivas G. , Balakrishnan Nair T. M. 
Published: October 2023

AbstractInterannual climate modes, especially the southern annular mode (SAM), significantly influence the wave climate modulation of the Indian Ocean (IO). The present study, aligned with previous research, identifies two crucial swell generation regions in the IO: the extratropical southern Indian Ocean (ETSI) and the tropical southern Indian Ocean (TSIO). The SAM, governing Southern Ocean surface winds, significantly shapes wave generation in these zones, thereby dominantly regulating IO wave conditions. Positive SAM phases shifts the westerlies poleward creating significant negative anomalies in the northern ETSI, reducing wave generation and swell propagation into the northern IO (NIO) basins, while the positive wind anomalies in the western TSIO creates a new swell generation area that directs swells towards the Arabian Sea, elevating wave heights there during monsoons. Conversely, negative SAM phases enhance TSIO easterlies, making it the primary IO swell source, increasing swell activity in the Bay of Bengal, notably during premonsoon and monsoon seasons. SAM impact expands beyond swells, influencing NIO wave climate by altering wind seas through Hadley cell (HC) circulation shifts. Positive SAM phases trigger NIO and midlatitude anomalous warming, intensifying HC and NIO surface winds in the next season, thereby affecting convection and subsequent sea surface temperature (SST) anomaly changes. The “SAM positive anomaly wind‐SST oscillations (SPAWSO)” pattern emerges, where warm SST anomalies in DJF and JJA precede increased surface winds in MAM and SON, thus increasing the wind‐sea conditions in the NIO. SPAWSO, hence, acts as a delayed mode, season‐dependent positive air–sea interaction cycle linked to positive SAM phases, significantly impacting NIO's wind‐sea dynamics. Thus the present study provides better insights into the long‐term wave prediction accuracy in the IO by considering the direct swell influence and SPAWSO‐driven wind‐sea changes, aiding preparations for changing wave dynamics and their impacts.
Meta‐analysis of social media influencer impact: Key antecedents and theoretical foundations
Authors: Han Jiseon , Balabanis George 
Published: October 2023

AbstractThis meta‐analytic review offers a comprehensive framework for studying social media influencers by integrating multiple theoretical perspectives and measures. It analyzes 250 effect sizes from 53 studies, highlighting the significance of credibility, trustworthiness, and perceived expertise of social media influencers in shaping attitudinal outcomes. Source Credibility Theory emerges as the most robust explanatory framework, while Parasocial Interaction Theory and Congruity Theory also play essential roles. For behavioral outcomes, Source Credibility Theory and Congruity Theory remain influential, with moderate effects observed for homophily and variables from the two‐step flow model. Methodological diversity, geographical context, platform context, product context, and influencer type contribute to variations in effect sizes. These findings provide insights into social media influencer influence dynamics and guide future research. Moreover, they contribute to theory development by shedding light on the mechanisms and conditions underlying social media influencer influence on consumer attitudes and behaviors.
In vitro characterization of bionanocomposites with green silver nanoparticles: A step towards sustainable wound healing materials
Authors: Trotta Federico , Dony Alna , Mok Monica , Grillo Alessandra , Whitehead‐Clarke Thomas , Homer‐Vanniasinkam Shervanthi , Kureshi Alvena 
Published: October 2023

AbstractThis study investigated the characterization, antifungal activity, and biocompatibility of green agar/silver and collagen/silver bionanocomposite films for wound healing and cell growth scaffolds. Silver nanoparticles (AgNPs) are known for their antimicrobial properties, but their toxicity and harsh synthesis limit their applications. To address this, green‐synthesized AgNPs G‐AgNPs were incorporated into agar/collagen suspensions at specific concentrations and three different G‐AgNP‐agar and two different G‐AgNP‐col bionanocomposite films were produced. Nanoparticle homogeneity and film quality were characterized through SEM analysis. Mechanical properties were tested using a uniaxial tensile tester, revealing that the bioplastic control samples exhibited UTS of 3.86 MPa compared to 0.60 MPa for collagen, a 6‐fold improvement. Viable cell metabolic activity derived from MTT assay showed that Col‐4%AgNPs and Bio‐30%AgNPs had a 42.9% and 51.6% increase in net metabolic activity respectively compared to control on day 4. Fluorescence microscopy confirmed enhanced cell adhesion and proliferation in G‐AgNP‐incorporated samples. Antifungal properties were evaluated against Cladosporium spores, able to cause severe diseases when in contact with human skins, following ISO 16869:2008 standards. The demonstrated unique properties and tunability of G‐AgNPs bionanocomposites can be employed in a variety of specialties for wound‐healing applications, to improve rate and quality of healing while reducing the risk of infection.
Effect of silica filler on peroxide cured ethylene propylene diene terpolymer insulation for large rocket motors
Authors: Jabez I. Kingstone Lesley , Das Urmila , Sudarshan Nakka 
Published: October 2023

AbstractNon‐compatibility with double base propellant and nitrate ester plasticized polyether based propellant and poor aging resistance limit the overall life of sulfur cured EPDM insulation and warranted the development of peroxide cured EPDM insulation in order to reap the full benefits of EPDM insulation. This article describes the effect of silica filler on the physical, mechanical, thermal, and ablative properties of peroxide cured EPDM insulation, free from chlorosulphonated polyethylene and filled with conventional precipitated silica, which has been validated for the requirements of large composite rocket motor casing. Significant findings, which have been corroborated by instrumental techniques viz. DSC, TGA, FTIR, and SEM are presented in this article.