bluuebunny/crossref_metadata_2025_split huggingface dataset:
Significance of red cell alloantibodies other than anti-D during pregnancy and their effect on the newborn: A case series
Authors: Nayak Sweta 
Published: November 2023

Contrary to well-established guidelines in developed countries, awareness regarding red cell alloantibodies in antenatal period are lacking in India. Investigating for indirect antiglobulin test (IAT) is mostly limited to the Rh D negative antenatal cases. This case series revisits this vital aspect of maternal and fetal safety. Instances of alloantibody other than anti-D are reported.Study was done in Transfusion Medicine department of a tertiary care hospital in North India during 2019-2020. IAT was performed not during the 1st or 2nd trimesters of pregnancy but as a routine compatibility test during delivery. Patients with positive IAT were further evaluated for the detection of alloantibody by using identification panel red cells. Result: Eight antenatal cases with irregular antibodies other than anti-D during 2019-2020 are described. Antibodies detected per patient were single (three cases of anti-E, one of anti-Fya, one of anti-M) or multiple (two cases of anti-E plus anti-c, one of anti-E plus anti-K). Direct antiglobulin test of four babies born to these mothers was found to be positive, one of whom was still born and rest recovered with medical management. Two other babies had DAT negative and two mothers presented late after still birth. Alloantibody titer indicated in patient with anti-E during mid-pregnancy had titer was undetectable by standard tube technique.Non anti-D alloantibodies can potentially affect fetus, asserting equal attention as anti-D. IAT should not be missed in pregnancy as it is common to investigations for compatibility as well as for fetal wellbeing assessment.
Exploring the Experience of Uundergraduate Students from Nursing Grand Round: A Conventional Content Analysis
Authors: M Javadinejad , F Bahramnezhad 
Published: November 2023

Introduction: Nursing grand rounds are one of the potential factors for providing up-to-date evidence to nurses and nursing students and their use at the patient's bedside. Identifying the visible and hidden angles of this experience can help to improve this approach. Based on this, this study was exploring the experience of undergraduate nursing students from Grand Round.
Methods: This study is part of a qualitative study with an exploratory sequential interventional combined approach that was conducted with the help of conventional content analysis. For this purpose, 25 undergraduate nursing students of the 7th semester, who had internship experience in intensive care units in the Grand Round method, were purposefully included in the study. Then, with the help of semi-structured, in-depth, and face-to-face interviews with an average of 40 to 60 minutes, the experiences of these participants were extracted and after recording and implementation, they were analyzed with the help of Granheim and Lundman's approach.
Results: The mean± SD age of these students was 21.3 ± 10.8 years. From a total of 25 interviews conducted with the participants, 423 primary codes were extracted. After merging the codes that had similar content and meaning, three main categories of internship purposefulness, withdrawal from island education and perceived challenges appeared with 9 subcategories.
Conclusion: Since the participants in the study claimed that with the help of this approach, education at the bedside is targeted and in fact, they are faced with a new approach in education, it is necessary to take steps to identify this approach and try to solve the challenge of this approach.
Caracterización de la gerencia de proyectos de construcción en la ciudad de Tunja
Authors: Sarmiento Rojas Jorge Andrés , Medina Suárez María Nuncia , Gutiérrez Junco Óscar Javier 
Published: November 2023

El presente libro es el compendio del proceso de investigación realizado en Tunja (Boyacá) por los autores en el año 2018, con la finalizad de identificar, analizar y caracterizar la gerencia de proyectos para el sector de la construcción en la ciudad. Esta investigación se realizó con un levantamiento de información primaria aplicado a cada uno de los gerentes o encargados de los proyectos en ejecución, para su posterior análisis, contextualización y presentación de los resultados.
Manajemen Pembiayaan Di MTs Bahrul Ulum Krawang Sari Natar Lampung Selatan
Authors: Indillah Muhammad , Yetri Yetri , Amirudin Amirudin 
Published: November 2023

Manajemen pembiayaan sekolah merupakan keseluruhan proses upaya memperoleh serta mendaya gunakan seluruh dana di sekolah. Mencari sebanyak mungkin sumber-sumber keuangan dan sumber-sumber untuk mendapatkan dana dari sumber-sumber keuangan. Berdasarkan hasil survey penulis dapat mengidentifikasi masalah yang antara lain: perencanaan keuangan (budgeting), pelaksanaan (accounting) dan pemeriksaan (auditing) belum terlaksana dengan baik. Penelitian ini menggunakan metode kualitatif. Sumber data dalam penelitian ini terdiri dari kepala Madrasah, Ketua Komite, TU, bendahara, waka kurikulum, waka kesiswaan, guru-guru. Pengumpulan data dalam penelitian ini menggunakan teknik wawancara, observasi dan dokumentasi. Analisis data dilakukan melalui tiga tahapan yaitu reduksi data, penyajian data dan menarik kesimpulan yang kemudian diuraikan secara deskriptif. Dengan implementasi manajemen pembiayaan melalui fungsi- fungsi manajemen keuangan yaitu perencanaan keuangan (budgeting), pelaksanaan (accounting), pemeriksaan (auditing). Implementasi manajemen pembiayaan melalui fungsi-fungsi manajemen keuangan di MTs Bahrul Ulum Krawang Sari Natar sudah berjalan sebagaimana mestinya. Melalui penelitian ini penulis merekomendasikan kepada pihak-pihak yang terkait dengan perencanaan keuangan (budgeting) agar dapat menambah jumlah sarana prasarana pendidikan berupa gedung kantor/belajar dan inventaris.
Implementasi Manajemen Mutu Terpadu di Madrasah Aliyah Negeri 1 Bandar Lampung
Authors: Nadia Putri , Patimah Siti , Subandi Subandi , Junaidah Junaidah , Ayu Sovia Mas 
Published: November 2023

Latar belakang penelitian ini adalah Tingginya minat masyarakat yang masih berlomba-lomba untuk memasukkan anaknya di MAN 1 Bandar Lampung, jumlah pendaftaran siswa baru setiap tahunnya mengalami peningkatan jumlah pendaftar walaupun tidak terlihat signifikan. Namun terlihat ada peningkatan jumlah pendaftar disetiap tahunnya. Hal ini juga karena banyaknya generasi keluarga siswa yang kembali menempuh pendidikan di MAN 1 Bandar Lampung. Tujuan penelitian ini untuk menggali tentang pelaksanaan manajemen mutu terpadu di MAN 1 Bandar Lampung. Penelitian ini menggunakan pendekatan deskriptif kualitatif. Pengumpulan data dilakukan dengan melakukan wawancara, observasi dan dokumentasi. Analisis data yang digunakan dalam penelitian ini dilakukan dengan mereduksi data, setelah itu disajikan dalam bentuk deskripsi dan diverifikasi dengan menarik kesimpulan. Hasil penelitian ini menunjukkan bahwa: Implementasi dalam manajemen mutu terpadu di MAN 1 Bandar Lampung, sudah baik yaitu secara terus-menerus diupayakan dengan mengedepankan layanan kepuasan pelanggan (Peserta didik), sudah melibatkan semua warga madrasah melalui rapat guru setiap satu bulan atau dua bulan sekali, mempunyai struktur organisasi yang mengandung kontrol, kepala madrasah membangun komitmen dengan cara memberdayakan seluruh warga madrasah sesuai dengan kompetensi dan kapasitas yang dimiliki untuk berkontribusi meningkatkan mutu, manajemen madrasah selalu melakukan upaya-upaya kreatif untuk memuaskan layanan peserta didiknya seperti mendatangkan motivator.
Harmonizing International Commercial Arbitration: A Special Focus on Time Limit to Setting Aside an Award
Authors: Gadkari Ahan Mohit 
Published: November 2023

Harmonizing international commercial arbitration with domestic courts is paramount in international commercial law. In this aspect, the time limit decided for setting aside an award is an essential aspect of the entire process of harmonization. By using in-depth analysis, this paper aimed to analyze the judicial practice of the period to set aside an award across common law jurisdictions. This paper contended that domestic courts lack the authority to extend the period for applying to vacate an award and some recurrent fact patterns that arise when parties attempt to argue for such discretion and how courts in other countries have addressed comparable instances. It delved into the harmonization of international commercial arbitration by considering the authority of domestic courts to extend the period for applying to vacate the award given that a significant reason for the success of the UNCITRAL Model Law on International Commercial Arbitration (Model Law) is the cross-jurisdictional consistency of standards that can result from the Model Law's uniform application, particularly concerning those provisions considered mandatory. While leaving aside common law jurisdictions that have not adopted the Model Law, one would expect that the Common Law jurisdictions that have adopted the UNCITRAL Model Law must be consistent in their interpretations. Then, a proper international jurisprudence will harmonize international commercial arbitration proceedings globally for the benefit of parties. However, such cross-border uniformity is difficult to establish, as the Model Law discussed in this paper showed. Article 34(3) of the Model Law on the time bar for setting aside an award, not providing domestic courts the authority to extend this time restriction, several unusual cases from Asian Model Law States imply that such authority exists.
KEYWORDS: International Commercial Arbitration, UNCITRAL, Model Law.
Promoting the Responsibility to Protect through Non-State Armed Groups: Overcoming the Legal and Regulatory Constraints
Authors: Nnawulezi Uche , Nwaechefu Hilary 
Published: November 2023

Promoting responsibility to protect through non-state armed groups will immensely reduce humanitarian crises around the globe. This paper aimed to analyze in detail the notion of responsibility to protect through non-state armed groups and its constitutive elements and set out a legal test that will expand the pre-existing notion of humanitarian intervention. In doing so, the paper advanced several conceptual arguments that focused on the responsibility to protect. The paper analyzed its views in light of contemporary developments on the responsibility to protect. The paper adopted a diagnostic approach based on a review of the literature and an evidence-based analysis of the humanitarian engagement of non-state armed groups. This paper showed the importance of reiterating that if the future of humanitarian intervention must be guaranteed, the need to take cognizance of the significant role of non-state armed groups in conflict mediation or intervention should not be overlooked. It is advanced that the continued neglect of non-state armed groups in conflict mediation or intervention portends a clog in responsibility to protect during armed conflicts.
KEYWORDS: Responsibility to Protect, Non-State Actors, Armed Groups.
An Overlooked Christian Palestinian Aramaic Witness of the “Dormition of Mary” in Codex Climaci Rescriptus (CCR IV)
Authors: Müller-Kessler Christa 
Published: November 2023

The Codex Climaci Rescriptus(CCR IV) contains a neglected text witness of the Dormition of Maryfrom the five-book cycle or “palm narrative”. It is one of the very early transmissions of this apocryphal text in Christian Palestinian Aramaic agreeing in closeness with the very late Ethiopic one of the 18th century.
The Gospel of Thomas and the Thomasine Tradition
Authors: Moldovan Petru 
Published: November 2023

The debates about various early ‘Christian’ communities are still in an incomplete and tumultuous never-ending process. This paper illustrates that the manufactured theories about ‘community’ or ‘tradition’ do not describe the particular social conditions of textualities such as the Gospel of Thomas. It is very common to the mainstream scholarship of the early Christianities to put together heterogeneous ideas and to understand them as forming a special type of singularity. This is, in our case, the idea of ‘apostle Thomas.’ The scholarly representatives have tried to use complex sets of borrowed methodologies in order to make the historical lines of flight of early Christianity ideas more appealing and to conceal the process of domestication of textualities as the Gospel of Thomas. They have intentionally constructed religious communities, several types of Christians, differences, and similarities; all these aspects have the purpose to join in one wide and domesticated ‘Thomasine’ tradition. This paper aims to follow the lines of flight as they are programmed by the Thomas-scholars in order to deconstruct such approaches and to provide an alternative reading perspective detached by any kind of theological agendum.
Whole Body Physiology Model to Simulate Respiratory Depression of Fentanyl and Associated Naloxone Reversal - A Model Informed Repeat Dosing Analysis
Authors: Baird Austin , White Steven , Das Rishi , Tatum Nathan , Bisgaard Erika 
Published: November 2023

Abstract

Opioid use in the United States and abroad is an endemic part of culture with yearly increases in overdose rates and deaths. As rates of overdose incidence increases, the use of the safe and effective reversal agent, naloxone, in the form of a nasal rescue spray is being fielded and used by emergency medical technicians (EMTs) at a greater and greater rate. Despite advances in deployment of these rescue products, deaths are continuing to increase. There is evidence that repeated dosing of a naloxone nasal spray (such as Narcan) is becoming more common due to the amount and type of opiate being abused. Despite the benefits of naloxone related to opioid reversals, we lack repeated dosing guidelines as a function of opiate and amount the patient has taken. Goal directed dosing is promising, where respiratory markers are being used as an indication of the patient recovery but require time and understanding by the EMT. We construct a whole-body model of the pharmacokinetics and dynamics of an opiate, fentanyl on respiratory depression. We then construct a model of nasal deposition and administration of naloxone to investigate repeat dosing requirements for large overdose scenarios. We demonstrate that naloxone is highly effective at reversing respiratory symptoms of the patient and recommend dosing requirements as a function of fentanyl amount administered. By designing the model to include circulation and respiration we investigate physiological markers that may be used in goal directed therapy rescue treatments.
Do Infants Expect Reciprocity Between Strangers?
Authors: Jin Kyong-sun , Ting Fransisca , He Zijing , Baillargeon Renee 
Published: November 2023

Abstract

Social scientists from different disciplines have long argued that direct reciprocity plays an important role in regulating social interactions between unrelated individuals. Here we examined whether 15-month-old infants (N = 160) would expect direct positive and negative reciprocity between strangers. In violation-of-expectation experiments, infants watched successive interactions between two strangers, agent1 and agent2. After agent1 acted positively toward agent2, infants were surprised if agent2 acted negatively toward agent1 in a new context. Similarly, after agent1 acted negatively toward agent2, infants were surprised if agent2 acted positively toward agent1 in a new context. Both responses were eliminated when agent2’s actions were not knowingly directed at agent1. Additional results indicated that infants viewed it as acceptable for agent2 to either respond in kind to agent1 or not engage with her further. By 15 months of age, infants thus already expect a modicum of reciprocity between strangers: Initial positive or negative actions are expected to set broad limits on reciprocal actions. This research adds weight to long-standing claims that direct reciprocity helps regulate interactions between unrelated individuals and, as such, is likely to depend on psychological systems that have evolved to support reciprocal reasoning and behavior.
Flexible Goal-directed Cognition and Inner-Speech in Schizophrenia Spectrum Disorders: from clinical data to computational modeling, and backward.
Authors: Granato Giovanni , Costanzo Raffaele , Borghi Anna , Mattera Andrea , Carruthers Sean , Rossell Susan , Baldassarre Gianluca 
Published: November 2023

Abstract
Flexible goal-directed human cognition is supported by many forms of self-directed manipulation of representations. Among them, Inner-Speech (IS; covert self-directed speech) acts on second-order representations (e.g., goals/sub-goals), empowering attention and feedback processing. Interestingly, patients with Schizophrenia Spectrum Disorders (SSD) show impaired Executive Functions (EF; e.g., cognitive flexibility) and, probably, a related IS alteration. However, fragmentary evidence and no computational modeling prevent a clear assessment of these processes and focused therapeutic interventions. Here, we address these issues by exploiting a translational approach that integrates experimental clinical data, machine learning, and computational modeling. First, we administered the Wisconsin Cards Sorting Test (WCST; a neuropsychological test probing cognitive flexibility) to SSD patients and computed the behavioural data with a data-driven clustering algorithm. Second, we extracted the cluster neuropsychological profiles with our theory-based validated computational model of the WCST.
Finally, we exploited our model to emulate an IS-based psychotherapeutic intervention for SSD subpopulations. We identified different SSD sub-populations and global trends (e.g., a descending feedback sensitivity); however, extremely different neuropsychological profiles emerged. In particular, `Relatively Intact' patients showed an unexpected profile (distraction/reasoning failures), quite divergent from the perseverative/rigid profile of the others. Importantly, the former showed no impact of Interfering-IS, while the others showed increased Interfering-IS strongly affecting their cognition. These differences highlight that SSD populations require a cluster-dependent individualisation of the intervention to achieve adequate cognitive performance. Overall, these results support a clear definition of neuropsychological profiles and the related Interfering-IS impact in SSD subpopulations, thus showing important implications for basic research (e.g., cognitive neuroscience) and clinical fields (clinical psychology and psychiatry).
Antiferromagnetic Artificial Neuron Modeling of Biological Neural Networks
Authors: Bradley Hannah , Quach Lily , Louis Steven , Tyberkevych Vasyl 
Published: November 2023

Abstract

Replicating neural responses observed in biological systems using artificial neural networks holds significant promise in the fields of medicine and engineering. In this study, we employ ultra-fast artificial neurons based on antiferromagnetic (AFM) spin Hall oscillators to emulate the biological withdrawal reflex responsible for self-preservation against noxious stimuli, such as pain or temperature. As a result of utilizing the dynamics of AFM neurons, we are able to construct an artificial neural network that can mimic the functionality and organization of the biological neural network responsible for this reflex. The unique features of AFM neurons, such as inhibition that stems from an effective AFM inertia, allow for the creation of biologically realistic neural network components, like the interneurons in the spinal cord and antagonist motor neurons. To showcase the effectiveness of AFM neuron modeling, we conduct simulations of various scenarios that define the withdrawal reflex, including responses to both weak and strong sensory stimuli, as well as voluntary suppression of the reflex.
Application of Mendelian randomization to explore the genetic association between drinking habits of different beverages and sleep disorder
Authors: Zhang Chao , Du Xiaoxun 
Published: November 2023

Abstract
Purpose
To provide genetic evidence for the relationship between drinking habits of various beverages (DHDB) and sleep disorders (SDL) and inform potential clinical treatments for lifestyle improvements.
Methods
We used a two-sample Mendelian randomization approach to investigate the genetic links between DHDB and SDL. DHDB variables included alcohol intake (ALI), alcohol intake frequency (ALF), high-frequency drinking with meals (HAL), tea intake (TEAI), coffee intake (COFI), and red wine intake (RWI). SDL variables included insomnia (INS), inhibit excitability (IE), and sleep duration (SD).
Results
The Mendelian randomization analysis revealed genetic associations between ALI and INS, ALF and IE, ALF and SD, HAL and INS, HAL and IE, HAL and SD, TEAI and IE, TEAI and SD, COFI and IE (P(IVW) < 0.05). However, no significant genetic associations were found between ALI and IE, ALI and SD, ALF and INS, TEAI and INS, COFI and INS, COFI and SD, RWI and INS, RWI and IE, RWI and SD (P(IVW) > 0.05).
Conclusions
It indicates that: (1) Alcohol may increase insomnia risk but not affect daytime sleepiness or sleep duration; (2) Frequent alcohol consumption may lead to daytime sleepiness and shorter sleep but doesn't raise insomnia risk; (3) Alcohol with meals may reduce insomnia, daytime sleepiness, and increase total sleep time; (4) Tea consumption isn't an insomnia risk and can reduce daytime drowsiness; (5) Coffee can reduce daytime drowsiness without causing insomnia; (6) Red wine isn't significantly linked to insomnia or daytime sleepiness. Reverse MR analysis suggests associations between sleep disturbances and alcohol and caffeine intake.
Biomechanical Role of Bone Grafting for Calcaneal Fracture Fixation in the Presence of Bone Defect: A Finite Element Analysis
Authors: Su Zhihao , Ding Ming , Zhu Ning , Cheung James Chung-Wai , Wong Duo Wai-Chi , Sun Wanju , Ni Ming 
Published: November 2023

Abstract

Background
The purpose of this study was to compare the biomechanical stress and stability of calcaneal fixations with and without bone defect, before and after bone grafting, through a computational approach.
Methods
A finite element model of foot-ankle complex was reconstructed, impoverished with a Sanders III calcaneal fracture without bone defect and with moderate and severe bone defects. Plate fixations with and without bone grafting were introduced with walking stance simulated. The stress and fragment displacement of the calcaneus were evaluated.
Results
Moderate and severe defect increased the calcaneus stress by 16.11% and 32.51%, respectively and subsequently decreased by 10.76% and 20.78% after bone grafting. The total displacement was increased by 3.99% and 24.26%, respectively by moderate and severe defect, while that of posterior joint facet displacement was 86.66% and 104.44%. The former was decreased by 25.73% and 35.96% after grafting, while that of the latter was reduced by 88.09% and 84.78% for moderate and severe defect, respectively.
Conclusions
Our FE prediction supported that bone grafting for fixation could enhance the stability and reduce the risk of secondary stress fracture in cases of bone defect in calcaneal fracture.